BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000622-TA|BGIBMGA000622-PA|IPR003599|Immunoglobulin subtype, IPR003598|Immunoglobulin subtype 2, IPR000577|Carbohydrate kinase, FGGY, IPR007110|Immunoglobulin-like, IPR013098|Immunoglobulin I-set, IPR010939|Protein of unknown function DUF1136 (4814 letters) Database: nematostella 59,808 sequences; 16,821,457 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SB_47306| Best HMM Match : I-set (HMM E-Value=0) 211 9e-54 SB_29786| Best HMM Match : I-set (HMM E-Value=0) 202 6e-51 SB_31699| Best HMM Match : No HMM Matches (HMM E-Value=.) 199 4e-50 SB_8818| Best HMM Match : I-set (HMM E-Value=0) 199 4e-50 SB_8817| Best HMM Match : I-set (HMM E-Value=0) 182 8e-45 SB_47305| Best HMM Match : I-set (HMM E-Value=0) 180 3e-44 SB_8819| Best HMM Match : I-set (HMM E-Value=0) 161 2e-38 SB_26711| Best HMM Match : I-set (HMM E-Value=0) 153 4e-36 SB_54054| Best HMM Match : No HMM Matches (HMM E-Value=.) 116 5e-25 SB_23359| Best HMM Match : I-set (HMM E-Value=0) 100 3e-20 SB_10606| Best HMM Match : I-set (HMM E-Value=0) 100 3e-20 SB_59380| Best HMM Match : No HMM Matches (HMM E-Value=.) 99 8e-20 SB_57926| Best HMM Match : I-set (HMM E-Value=3.5e-39) 97 3e-19 SB_24472| Best HMM Match : I-set (HMM E-Value=0) 97 4e-19 SB_33342| Best HMM Match : No HMM Matches (HMM E-Value=.) 96 5e-19 SB_37927| Best HMM Match : No HMM Matches (HMM E-Value=.) 96 7e-19 SB_19226| Best HMM Match : I-set (HMM E-Value=0) 93 7e-18 SB_40832| Best HMM Match : No HMM Matches (HMM E-Value=.) 88 1e-16 SB_45852| Best HMM Match : I-set (HMM E-Value=0) 87 3e-16 SB_29237| Best HMM Match : I-set (HMM E-Value=0) 86 6e-16 SB_1528| Best HMM Match : No HMM Matches (HMM E-Value=.) 86 8e-16 SB_8553| Best HMM Match : No HMM Matches (HMM E-Value=.) 85 1e-15 SB_5639| Best HMM Match : No HMM Matches (HMM E-Value=.) 84 3e-15 SB_10900| Best HMM Match : I-set (HMM E-Value=0) 80 4e-14 SB_43700| Best HMM Match : SRCR (HMM E-Value=0) 79 9e-14 SB_41825| Best HMM Match : No HMM Matches (HMM E-Value=.) 78 2e-13 SB_40708| Best HMM Match : SRCR (HMM E-Value=0) 77 4e-13 SB_50799| Best HMM Match : I-set (HMM E-Value=0) 77 5e-13 SB_40971| Best HMM Match : No HMM Matches (HMM E-Value=.) 76 8e-13 SB_8388| Best HMM Match : ig (HMM E-Value=8.80001e-41) 75 2e-12 SB_51089| Best HMM Match : I-set (HMM E-Value=1.4e-38) 75 2e-12 SB_31697| Best HMM Match : No HMM Matches (HMM E-Value=.) 74 2e-12 SB_26454| Best HMM Match : I-set (HMM E-Value=7e-12) 73 8e-12 SB_12405| Best HMM Match : I-set (HMM E-Value=8.8e-21) 72 1e-11 SB_11883| Best HMM Match : I-set (HMM E-Value=0) 70 5e-11 SB_52575| Best HMM Match : No HMM Matches (HMM E-Value=.) 69 7e-11 SB_41626| Best HMM Match : No HMM Matches (HMM E-Value=.) 69 7e-11 SB_53570| Best HMM Match : Y_phosphatase (HMM E-Value=0) 69 9e-11 SB_41623| Best HMM Match : No HMM Matches (HMM E-Value=.) 69 9e-11 SB_14313| Best HMM Match : I-set (HMM E-Value=1.8e-21) 68 2e-10 SB_30290| Best HMM Match : I-set (HMM E-Value=1.4e-21) 67 4e-10 SB_24384| Best HMM Match : I-set (HMM E-Value=4.3e-31) 66 5e-10 SB_14894| Best HMM Match : No HMM Matches (HMM E-Value=.) 66 9e-10 SB_31893| Best HMM Match : I-set (HMM E-Value=2e-22) 66 9e-10 SB_34975| Best HMM Match : F5_F8_type_C (HMM E-Value=0) 65 1e-09 SB_17403| Best HMM Match : I-set (HMM E-Value=0) 64 2e-09 SB_57324| Best HMM Match : ig (HMM E-Value=1e-26) 63 6e-09 SB_2157| Best HMM Match : ig (HMM E-Value=9e-19) 63 6e-09 SB_20844| Best HMM Match : Ion_trans (HMM E-Value=0) 63 6e-09 SB_27122| Best HMM Match : I-set (HMM E-Value=1.9e-39) 62 1e-08 SB_33752| Best HMM Match : I-set (HMM E-Value=3.7e-15) 61 2e-08 SB_9092| Best HMM Match : No HMM Matches (HMM E-Value=.) 61 2e-08 SB_3191| Best HMM Match : ig (HMM E-Value=3.5e-16) 60 4e-08 SB_41624| Best HMM Match : No HMM Matches (HMM E-Value=.) 60 4e-08 SB_13651| Best HMM Match : I-set (HMM E-Value=4e-17) 60 6e-08 SB_59628| Best HMM Match : I-set (HMM E-Value=5e-21) 60 6e-08 SB_36553| Best HMM Match : No HMM Matches (HMM E-Value=.) 59 1e-07 SB_37863| Best HMM Match : I-set (HMM E-Value=3.1e-14) 58 2e-07 SB_51604| Best HMM Match : I-set (HMM E-Value=2.3e-21) 58 2e-07 SB_39029| Best HMM Match : ig (HMM E-Value=6e-10) 58 2e-07 SB_58150| Best HMM Match : ig (HMM E-Value=3.7e-24) 57 4e-07 SB_32327| Best HMM Match : ig (HMM E-Value=7.9e-23) 57 4e-07 SB_14261| Best HMM Match : ig (HMM E-Value=0) 57 4e-07 SB_15392| Best HMM Match : No HMM Matches (HMM E-Value=.) 56 5e-07 SB_38293| Best HMM Match : No HMM Matches (HMM E-Value=.) 56 9e-07 SB_29770| Best HMM Match : ig (HMM E-Value=3.4e-05) 55 2e-06 SB_54662| Best HMM Match : No HMM Matches (HMM E-Value=.) 55 2e-06 SB_29852| Best HMM Match : No HMM Matches (HMM E-Value=.) 54 2e-06 SB_16673| Best HMM Match : No HMM Matches (HMM E-Value=.) 54 2e-06 SB_55336| Best HMM Match : No HMM Matches (HMM E-Value=.) 54 2e-06 SB_55607| Best HMM Match : ig (HMM E-Value=4.6e-17) 54 3e-06 SB_37708| Best HMM Match : No HMM Matches (HMM E-Value=.) 54 3e-06 SB_16652| Best HMM Match : I-set (HMM E-Value=1.2e-37) 54 3e-06 SB_5575| Best HMM Match : No HMM Matches (HMM E-Value=.) 54 3e-06 SB_30961| Best HMM Match : I-set (HMM E-Value=0) 54 4e-06 SB_10041| Best HMM Match : ig (HMM E-Value=3.5e-06) 54 4e-06 SB_46550| Best HMM Match : Asn_synthase (HMM E-Value=0) 52 9e-06 SB_9202| Best HMM Match : ig (HMM E-Value=5e-40) 52 9e-06 SB_45516| Best HMM Match : I-set (HMM E-Value=1.1e-26) 52 1e-05 SB_43869| Best HMM Match : ig (HMM E-Value=2.7e-06) 52 1e-05 SB_9034| Best HMM Match : No HMM Matches (HMM E-Value=.) 52 1e-05 SB_3465| Best HMM Match : No HMM Matches (HMM E-Value=.) 51 2e-05 SB_22798| Best HMM Match : Cadherin (HMM E-Value=0) 51 2e-05 SB_56900| Best HMM Match : I-set (HMM E-Value=8e-10) 51 3e-05 SB_54071| Best HMM Match : No HMM Matches (HMM E-Value=.) 51 3e-05 SB_33923| Best HMM Match : No HMM Matches (HMM E-Value=.) 50 3e-05 SB_2143| Best HMM Match : ig (HMM E-Value=1.9e-09) 50 3e-05 SB_30548| Best HMM Match : I-set (HMM E-Value=2.1e-11) 50 3e-05 SB_45888| Best HMM Match : Pkinase_Tyr (HMM E-Value=1.4e-25) 50 5e-05 SB_6364| Best HMM Match : No HMM Matches (HMM E-Value=.) 50 5e-05 SB_39808| Best HMM Match : EGF_CA (HMM E-Value=6.3e-35) 50 6e-05 SB_28651| Best HMM Match : ig (HMM E-Value=1.4e-09) 50 6e-05 SB_56353| Best HMM Match : I-set (HMM E-Value=6.3e-15) 49 8e-05 SB_24015| Best HMM Match : I-set (HMM E-Value=2.7e-21) 49 8e-05 SB_52866| Best HMM Match : No HMM Matches (HMM E-Value=.) 49 8e-05 SB_8401| Best HMM Match : ig (HMM E-Value=8.1e-22) 49 1e-04 SB_21597| Best HMM Match : ig (HMM E-Value=2.9e-14) 49 1e-04 SB_52846| Best HMM Match : ig (HMM E-Value=9e-12) 48 1e-04 SB_12096| Best HMM Match : ig (HMM E-Value=9.4e-33) 48 1e-04 SB_26137| Best HMM Match : Plasmodium_HRP (HMM E-Value=0.27) 48 2e-04 SB_2034| Best HMM Match : No HMM Matches (HMM E-Value=.) 48 2e-04 SB_43033| Best HMM Match : I-set (HMM E-Value=3.3e-18) 48 2e-04 SB_15415| Best HMM Match : No HMM Matches (HMM E-Value=.) 48 2e-04 SB_42486| Best HMM Match : Pkinase_Tyr (HMM E-Value=0) 48 2e-04 SB_12208| Best HMM Match : ig (HMM E-Value=6.9e-30) 48 2e-04 SB_5499| Best HMM Match : No HMM Matches (HMM E-Value=.) 47 3e-04 SB_26664| Best HMM Match : I-set (HMM E-Value=7.6e-06) 47 4e-04 SB_24434| Best HMM Match : No HMM Matches (HMM E-Value=.) 47 4e-04 SB_59087| Best HMM Match : ig (HMM E-Value=1.5e-27) 46 6e-04 SB_50854| Best HMM Match : ig (HMM E-Value=6.1e-27) 46 6e-04 SB_33962| Best HMM Match : No HMM Matches (HMM E-Value=.) 46 6e-04 SB_27603| Best HMM Match : ig (HMM E-Value=2.9e-10) 46 6e-04 SB_53873| Best HMM Match : Fibrinogen_C (HMM E-Value=0) 46 8e-04 SB_50833| Best HMM Match : Thyroglobulin_1 (HMM E-Value=1.1e-08) 46 8e-04 SB_48846| Best HMM Match : Pkinase_Tyr (HMM E-Value=8.1e-16) 46 8e-04 SB_994| Best HMM Match : I-set (HMM E-Value=6e-15) 46 0.001 SB_56444| Best HMM Match : fn3 (HMM E-Value=1.2e-21) 46 0.001 SB_29125| Best HMM Match : I-set (HMM E-Value=1.8e-09) 46 0.001 SB_53160| Best HMM Match : No HMM Matches (HMM E-Value=.) 45 0.001 SB_51910| Best HMM Match : ig (HMM E-Value=4.9e-05) 45 0.001 SB_39770| Best HMM Match : TolA (HMM E-Value=0.33) 45 0.001 SB_13504| Best HMM Match : No HMM Matches (HMM E-Value=.) 45 0.001 SB_31858| Best HMM Match : I-set (HMM E-Value=3.7e-08) 45 0.001 SB_19207| Best HMM Match : ig (HMM E-Value=1.2e-11) 45 0.001 SB_18521| Best HMM Match : ig (HMM E-Value=7.5e-11) 45 0.001 SB_44830| Best HMM Match : I-set (HMM E-Value=1.1e-08) 45 0.002 SB_37776| Best HMM Match : fn3 (HMM E-Value=1.4e-22) 44 0.002 SB_25692| Best HMM Match : I-set (HMM E-Value=2e-20) 44 0.002 SB_19559| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.002 SB_16914| Best HMM Match : I-set (HMM E-Value=2.3e-10) 44 0.002 SB_13005| Best HMM Match : PSI (HMM E-Value=2.9e-11) 44 0.002 SB_43138| Best HMM Match : Pox_A_type_inc (HMM E-Value=1.3e-14) 43 0.005 SB_33085| Best HMM Match : Trypsin (HMM E-Value=0) 43 0.005 SB_35648| Best HMM Match : I-set (HMM E-Value=8.5e-05) 43 0.005 SB_23794| Best HMM Match : ig (HMM E-Value=3.1e-07) 43 0.007 SB_2033| Best HMM Match : No HMM Matches (HMM E-Value=.) 43 0.007 SB_43971| Best HMM Match : I-set (HMM E-Value=1.7e-09) 43 0.007 SB_29801| Best HMM Match : Collagen (HMM E-Value=3.2e-12) 42 0.009 SB_3251| Best HMM Match : I-set (HMM E-Value=1.8e-07) 42 0.009 SB_56336| Best HMM Match : Ag332 (HMM E-Value=5.1) 42 0.012 SB_49916| Best HMM Match : ig (HMM E-Value=8.5e-06) 42 0.012 SB_25723| Best HMM Match : Vicilin_N (HMM E-Value=0.0045) 42 0.012 SB_43939| Best HMM Match : I-set (HMM E-Value=1.3e-14) 42 0.016 SB_1939| Best HMM Match : No HMM Matches (HMM E-Value=.) 42 0.016 SB_49663| Best HMM Match : TolA (HMM E-Value=0.059) 42 0.016 SB_41418| Best HMM Match : EGF_CA (HMM E-Value=0) 41 0.021 SB_24813| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.021 SB_1718| Best HMM Match : I-set (HMM E-Value=3.8e-07) 41 0.021 SB_44749| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.021 SB_26428| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.021 SB_10779| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.021 SB_50998| Best HMM Match : No HMM Matches (HMM E-Value=.) 41 0.028 SB_42485| Best HMM Match : Pkinase_Tyr (HMM E-Value=0) 41 0.028 SB_10883| Best HMM Match : ig (HMM E-Value=7.00649e-43) 41 0.028 SB_43084| Best HMM Match : ig (HMM E-Value=9.7e-23) 41 0.028 SB_37145| Best HMM Match : ig (HMM E-Value=8e-07) 40 0.037 SB_28081| Best HMM Match : ig (HMM E-Value=2e-08) 40 0.037 SB_21023| Best HMM Match : I-set (HMM E-Value=2e-07) 40 0.037 SB_42222| Best HMM Match : ig (HMM E-Value=2.1e-17) 40 0.037 SB_37828| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.037 SB_26678| Best HMM Match : I-set (HMM E-Value=1e-07) 40 0.037 SB_10221| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.037 SB_10219| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.037 SB_29692| Best HMM Match : ig (HMM E-Value=5.4e-12) 40 0.049 SB_21223| Best HMM Match : I-set (HMM E-Value=2.8e-11) 40 0.049 SB_33134| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.049 SB_20290| Best HMM Match : ig (HMM E-Value=2.9e-15) 40 0.049 SB_24046| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.065 SB_33855| Best HMM Match : No HMM Matches (HMM E-Value=.) 39 0.086 SB_18843| Best HMM Match : I-set (HMM E-Value=1e-07) 39 0.086 SB_11246| Best HMM Match : ig (HMM E-Value=7.5e-07) 39 0.11 SB_1675| Best HMM Match : ig (HMM E-Value=5.6e-05) 39 0.11 SB_43870| Best HMM Match : Pkinase_Tyr (HMM E-Value=0) 39 0.11 SB_35812| Best HMM Match : Atrophin-1 (HMM E-Value=0.23) 39 0.11 SB_23775| Best HMM Match : Tropomyosin (HMM E-Value=0) 39 0.11 SB_23345| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.15 SB_50677| Best HMM Match : I-set (HMM E-Value=6.7e-11) 38 0.15 SB_40656| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.20 SB_26233| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.20 SB_16822| Best HMM Match : I-set (HMM E-Value=1.3e-07) 38 0.20 SB_1246| Best HMM Match : Mito_carr (HMM E-Value=1.4013e-45) 38 0.20 SB_38167| Best HMM Match : Collagen (HMM E-Value=7e-12) 38 0.20 SB_47033| Best HMM Match : WAP (HMM E-Value=1.8e-38) 38 0.26 SB_57573| Best HMM Match : 7tm_2 (HMM E-Value=3.7e-40) 38 0.26 SB_50620| Best HMM Match : Lectin_C (HMM E-Value=2.1e-14) 38 0.26 SB_44087| Best HMM Match : I-set (HMM E-Value=1.5e-05) 38 0.26 SB_12530| Best HMM Match : I-set (HMM E-Value=3e-05) 38 0.26 SB_11355| Best HMM Match : I-set (HMM E-Value=1.5e-05) 38 0.26 SB_7591| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.26 SB_48288| Best HMM Match : ig (HMM E-Value=6.9e-08) 37 0.35 SB_50351| Best HMM Match : I-set (HMM E-Value=0.00016) 37 0.35 SB_24929| Best HMM Match : ig (HMM E-Value=8.2e-06) 37 0.35 SB_21954| Best HMM Match : V-set (HMM E-Value=0.011) 37 0.35 SB_11731| Best HMM Match : ig (HMM E-Value=1e-06) 37 0.35 SB_43527| Best HMM Match : Trypsin (HMM E-Value=0) 37 0.46 SB_30644| Best HMM Match : No HMM Matches (HMM E-Value=.) 37 0.46 SB_29861| Best HMM Match : RRM_1 (HMM E-Value=1.10002e-42) 37 0.46 SB_17408| Best HMM Match : I-set (HMM E-Value=7.4e-06) 37 0.46 SB_53466| Best HMM Match : SCP (HMM E-Value=2.4e-27) 37 0.46 SB_48507| Best HMM Match : TolA (HMM E-Value=1) 37 0.46 SB_11578| Best HMM Match : ig (HMM E-Value=3.3e-23) 37 0.46 SB_3034| Best HMM Match : I-set (HMM E-Value=5e-09) 37 0.46 SB_56618| Best HMM Match : DUF1213 (HMM E-Value=0.022) 36 0.61 SB_55200| Best HMM Match : E-MAP-115 (HMM E-Value=0.85) 36 0.61 SB_49614| Best HMM Match : E-MAP-115 (HMM E-Value=0.85) 36 0.61 SB_40579| Best HMM Match : E-MAP-115 (HMM E-Value=0.85) 36 0.61 SB_33143| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 0.61 SB_54309| Best HMM Match : SH2 (HMM E-Value=5.1e-17) 36 0.61 SB_26345| Best HMM Match : DUF1531 (HMM E-Value=2.4) 36 0.61 SB_23339| Best HMM Match : I-set (HMM E-Value=1.3e-07) 36 0.61 SB_18255| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 0.61 SB_15709| Best HMM Match : CAP_GLY (HMM E-Value=0) 36 0.61 SB_6057| Best HMM Match : ig (HMM E-Value=7.3e-06) 36 0.61 SB_43663| Best HMM Match : F-box (HMM E-Value=4e-07) 36 0.80 SB_42146| Best HMM Match : GYF (HMM E-Value=5.7e-15) 36 0.80 SB_36901| Best HMM Match : I-set (HMM E-Value=7.3e-09) 36 0.80 SB_28769| Best HMM Match : ig (HMM E-Value=1e-06) 36 0.80 SB_25318| Best HMM Match : fn3 (HMM E-Value=2e-15) 36 0.80 SB_18127| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 0.80 SB_58320| Best HMM Match : I-set (HMM E-Value=0.0099) 36 0.80 SB_47230| Best HMM Match : I-set (HMM E-Value=0.0028) 36 0.80 SB_46724| Best HMM Match : I-set (HMM E-Value=6.1e-11) 36 0.80 SB_41408| Best HMM Match : I-set (HMM E-Value=0.0042) 36 0.80 SB_53713| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 1.1 SB_53232| Best HMM Match : OAR (HMM E-Value=0.92) 36 1.1 SB_39065| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 1.1 SB_31717| Best HMM Match : I-set (HMM E-Value=2.9e-10) 36 1.1 SB_20109| Best HMM Match : I-set (HMM E-Value=2e-05) 36 1.1 SB_52206| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 1.1 SB_46304| Best HMM Match : Laminin_G_2 (HMM E-Value=0) 36 1.1 SB_27034| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 1.1 SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.4 SB_13773| Best HMM Match : TolA (HMM E-Value=0.042) 35 1.4 SB_8750| Best HMM Match : Neuromodulin (HMM E-Value=5.7) 35 1.4 SB_5736| Best HMM Match : I-set (HMM E-Value=0.0048) 35 1.4 SB_47260| Best HMM Match : ig (HMM E-Value=4.3e-13) 35 1.4 SB_6962| Best HMM Match : I-set (HMM E-Value=0.0042) 35 1.4 SB_53159| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.9 SB_44172| Best HMM Match : Pkinase_Tyr (HMM E-Value=6.3e-20) 35 1.9 SB_30807| Best HMM Match : I-set (HMM E-Value=7.8e-08) 35 1.9 SB_22350| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.9 SB_21400| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.9 SB_20351| Best HMM Match : I-set (HMM E-Value=1.9e-13) 35 1.9 SB_11517| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.9 SB_3226| Best HMM Match : RNA_pol_Rpb2_1 (HMM E-Value=0.021) 35 1.9 SB_26427| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.9 SB_20144| Best HMM Match : E-MAP-115 (HMM E-Value=0.41) 35 1.9 SB_16370| Best HMM Match : I-set (HMM E-Value=0.0024) 35 1.9 SB_15350| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 1.9 SB_50666| Best HMM Match : ig (HMM E-Value=2.8e-20) 34 2.5 SB_39538| Best HMM Match : VWA (HMM E-Value=0) 34 2.5 SB_35470| Best HMM Match : PAN (HMM E-Value=2.9e-08) 34 2.5 SB_19232| Best HMM Match : UCR_TM (HMM E-Value=5.1) 34 2.5 SB_7833| Best HMM Match : I-set (HMM E-Value=0.0042) 34 2.5 SB_53860| Best HMM Match : fn3 (HMM E-Value=3.6e-07) 34 3.2 SB_33494| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 3.2 SB_31639| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 3.2 SB_18619| Best HMM Match : I-set (HMM E-Value=7.8e-08) 34 3.2 SB_5458| Best HMM Match : E-MAP-115 (HMM E-Value=0.3) 34 3.2 SB_427| Best HMM Match : I-set (HMM E-Value=1.8e-12) 34 3.2 SB_30426| Best HMM Match : CXC (HMM E-Value=2.8) 34 3.2 SB_26474| Best HMM Match : No HMM Matches (HMM E-Value=.) 34 3.2 SB_8304| Best HMM Match : PLAT (HMM E-Value=0) 34 3.2 SB_6305| Best HMM Match : Adeno_E3_CR2 (HMM E-Value=0.096) 34 3.2 SB_50253| Best HMM Match : HYR (HMM E-Value=2.6e-20) 33 4.3 SB_47007| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.3 SB_42609| Best HMM Match : I-set (HMM E-Value=1.3) 33 4.3 SB_42014| Best HMM Match : Myosin_tail_1 (HMM E-Value=0.083) 33 4.3 SB_33884| Best HMM Match : I-set (HMM E-Value=7e-08) 33 4.3 SB_29610| Best HMM Match : Extensin_2 (HMM E-Value=2.3) 33 4.3 SB_12442| Best HMM Match : zf-MYND (HMM E-Value=0.0028) 33 4.3 SB_2459| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.3 SB_46756| Best HMM Match : zf-C2H2 (HMM E-Value=4.60046e-42) 33 4.3 SB_44178| Best HMM Match : I-set (HMM E-Value=0.52) 33 4.3 SB_42560| Best HMM Match : ig (HMM E-Value=2.4e-06) 33 4.3 SB_36607| Best HMM Match : Vicilin_N (HMM E-Value=3.7) 33 4.3 SB_33276| Best HMM Match : Glyco_transf_43 (HMM E-Value=0) 33 4.3 SB_28606| Best HMM Match : PAN (HMM E-Value=4.6e-10) 33 4.3 SB_28335| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.3 SB_25763| Best HMM Match : MgtE_N (HMM E-Value=1.9) 33 4.3 SB_19973| Best HMM Match : I-set (HMM E-Value=2.8e-08) 33 4.3 SB_1300| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 4.3 SB_54138| Best HMM Match : rve (HMM E-Value=6.8e-24) 33 5.7 SB_51947| Best HMM Match : 7tm_1 (HMM E-Value=1.4013e-45) 33 5.7 SB_45950| Best HMM Match : fn3 (HMM E-Value=3e-13) 33 5.7 SB_30292| Best HMM Match : fn3 (HMM E-Value=1.2e-12) 33 5.7 SB_28604| Best HMM Match : FerB (HMM E-Value=5.19994e-41) 33 5.7 SB_28014| Best HMM Match : HOOK (HMM E-Value=1.8e-13) 33 5.7 SB_21874| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 5.7 SB_18760| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 5.7 SB_11738| Best HMM Match : SH3_2 (HMM E-Value=3.7e-32) 33 5.7 SB_3082| Best HMM Match : ig (HMM E-Value=1.5e-17) 33 5.7 SB_56497| Best HMM Match : Extensin_2 (HMM E-Value=0.16) 33 5.7 SB_34910| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 5.7 SB_3422| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 5.7 SB_50210| Best HMM Match : I-set (HMM E-Value=0.11) 33 7.5 SB_28589| Best HMM Match : ig (HMM E-Value=1.1e-05) 33 7.5 SB_17203| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 7.5 SB_14859| Best HMM Match : SEA (HMM E-Value=0.01) 33 7.5 SB_10643| Best HMM Match : ShTK (HMM E-Value=2.9e-23) 33 7.5 SB_48968| Best HMM Match : Dehydrin (HMM E-Value=0.99) 33 7.5 SB_31398| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 7.5 SB_21196| Best HMM Match : I-set (HMM E-Value=1.3) 33 7.5 SB_7500| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 7.5 SB_1762| Best HMM Match : I-set (HMM E-Value=2.8e-12) 33 7.5 SB_55799| Best HMM Match : Na_trans_assoc (HMM E-Value=1.5) 32 9.9 SB_52732| Best HMM Match : M (HMM E-Value=0.019) 32 9.9 SB_29011| Best HMM Match : ig (HMM E-Value=2.7e-06) 32 9.9 SB_20689| Best HMM Match : Gelsolin (HMM E-Value=0.00029) 32 9.9 SB_812| Best HMM Match : FH2 (HMM E-Value=0) 32 9.9 SB_57625| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 9.9 SB_56996| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 9.9 SB_51340| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 9.9 SB_42488| Best HMM Match : ig (HMM E-Value=4.2e-06) 32 9.9 SB_36059| Best HMM Match : TolA (HMM E-Value=0.1) 32 9.9 SB_28927| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 9.9 SB_9820| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 9.9 SB_6600| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 9.9 SB_3562| Best HMM Match : Ribosomal_60s (HMM E-Value=2.1) 32 9.9 >SB_47306| Best HMM Match : I-set (HMM E-Value=0) Length = 1260 Score = 211 bits (516), Expect = 9e-54 Identities = 209/885 (23%), Positives = 360/885 (40%), Gaps = 100/885 (11%) Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028 K P +++++ Q +VE E C ++ G P VEW GKPL + P Y+ Sbjct: 424 KGTAPTILSEMKPQ-QVVEGEDVMLACAVS--GKPEPTVEWLKEGKPLSRDSHVRPKYEA 480 Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIR 4088 + F ED Y C ATN G + A ++ KP I P+ + Sbjct: 481 EIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEI----SAPESTTPV---- 532 Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148 E + P+ +E++ A PV L D +V G+ A+ RVTG PKP V W +G Sbjct: 533 -AETALMSKPKD-LEKTGA---PVIKELKD-TSVPIGQEAKLDARVTGSPKPEVEWFKDG 586 Query: 4149 NTIVNGSRYKLTYD---GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDD 4205 + + R+ D ++ I + D GK + I L + + Sbjct: 587 KVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSI----KE 642 Query: 4206 YRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEW 4265 P D + + T + +ER ++ + D R + + + EPE EW Sbjct: 643 ETETAPEKVEPTADVGVKEELTAPKFMD--KERGPIEVEEGEDVRLKTRVRGQPEPEIEW 700 Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPG-----------DKVTSNTV 4314 ++ + + E N E + E+ E T Y + + Sbjct: 701 LRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKA 760 Query: 4315 AKSMAQRYEDNLDQTEEVTEQRVQKKVT----QKPRIPDPSESTVHGKEVHVAKQK---- 4366 +A + + + E +Q V+ +T Q P++ + ++ + KE + K K Sbjct: 761 PAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKV-EWLKNNIRVKESYRIKSKADND 819 Query: 4367 ----QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRV 4422 ++ D+ + + + + + +A RV PVKPS F K++P Sbjct: 820 TATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRV---PVKPS----FVTKLKPTEA 872 Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-LIIRQVFVEDSAVF 4481 E +ARF+V+ G P P ++W+ I F+ + L++ + + DS Sbjct: 873 VEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGTI 932 Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTSGQLVRLDTKVTGT 4540 +A N G A+L V+E+ + P F Q + V G+ + + + V Sbjct: 933 KCIATNEAGKVTSRADLNVKER-------LFAPVFEDEEQGPIKVQEGEEISIKSVVKAK 985 Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600 DV W+KNGK ++ + + D T+ + I A DSG+Y C A NS G+ A Sbjct: 986 PKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGK----AS 1041 Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660 S+ K PK P++I ++ + EG+ +C++ GKP P+V+W K D Sbjct: 1042 RTYSVEVEKKVPKGHA------PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDD 1095 Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-------- 4712 K + + + TL++ +A EDE Y C A NS G V+ +A+L+V Sbjct: 1096 KPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPI 1155 Query: 4713 --------------TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758 +PD+ P + L D+VV G+ A+ +IT KP ++W+++G Sbjct: 1156 SPEPVSPVFEEPVKAEPDEGTVAPVIEGLNDVVVPLGREAKLDARITGSPKPEVEWIKDG 1215 Query: 4759 ALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQ 4801 ++ + F + + L+I + ED G + C A G+ Sbjct: 1216 QVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 170 bits (413), Expect = 3e-41 Identities = 127/446 (28%), Positives = 199/446 (44%), Gaps = 48/446 (10%) Query: 4396 TQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP 4455 T + V PVKPS F KKM+P E +ARF+V+ G P P ++W+R I + Sbjct: 220 TAKLTVNVPVKPS----FVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKE 275 Query: 4456 DFQIH-TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP 4514 F + T + L+I + ED+ VF VA N G A+L V+E++ P Sbjct: 276 RFHVEETGEDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKERQ-------FAP 328 Query: 4515 SFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 F V + G + + + DV W NGK ++ I T++L I Sbjct: 329 IFEDEQMGPVILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAI 388 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633 + A +D+G+Y C A N G+A + V A K P I+ +K + Sbjct: 389 ISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQAPK----------GTAPTILSEMKPQQ 438 Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V EG+ + +C + GKP PTV+W K K + + + A+ TL A EDE Y Sbjct: 439 VVEGEDVMLACAVSGKPEPTVEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALY 498 Query: 4694 KCVAYNSAGRVTVAAKLKVTQ-PD----------------------QADNLPALTPLRDI 4730 CVA N+ G V+ +A+L+V + P+ + P + L+D Sbjct: 499 TCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALMSKPKDLEKTGAPVIKELKDT 558 Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDT 4788 V GQ A+ ++T KP ++W ++G ++ + F + + V L+I + ED Sbjct: 559 SVPIGQEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDA 618 Query: 4789 GTFTCRATTAAGQVETSAKLVVKSKT 4814 G + C A G+VE A L +K +T Sbjct: 619 GKYKCIAFNEKGEVEAEANLSIKEET 644 Score = 165 bits (402), Expect = 6e-40 Identities = 115/441 (26%), Positives = 189/441 (42%), Gaps = 20/441 (4%) Query: 4374 GDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVE 4433 G+ E ++ E TE + V + + P K+ P V E E R + Sbjct: 630 GEVEAEANLSIKEETETAPEKVEPTADVGVKEELTAPKFMDKERGPIEVEEGEDVRLKTR 689 Query: 4434 FDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493 G+P P I+W R ++ S + + + + + +L + V VED+A + VA N G A+ Sbjct: 690 VRGQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAE 749 Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553 L+V+ K G V P Q + V Q+V+L T + V WLKN + Sbjct: 750 QDFELIVKFKAPAG----VAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIR 805 Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613 V+ R K ++ T TL I ++ +D G Y+CV N G +A V +P Sbjct: 806 VKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVP------- 858 Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673 P + LK EG F K+ G P P V+W+ G I F+ Sbjct: 859 -------VKPSFVTKLKPTEAVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRFEE 911 Query: 4674 TADE-YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732 +E ++L +++ D G KC+A N AG+VT A L V + A I V Sbjct: 912 VGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFED-EEQGPIKV 970 Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792 EG+ K+ + +K K ++W++ G + ++ + + + I +D+G +T Sbjct: 971 QEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYT 1030 Query: 4793 CRATTAAGQVETSAKLVVKSK 4813 C AT + G+ + + V+ K Sbjct: 1031 CEATNSVGKASRTYSVEVEKK 1051 Score = 160 bits (389), Expect = 2e-38 Identities = 120/436 (27%), Positives = 191/436 (43%), Gaps = 37/436 (8%) Query: 4411 PIFT-KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 PIF ++M P + + ++ + +P P + WY P++++P I + L Sbjct: 328 PIFEDEQMGPVILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLA 387 Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529 I +ED+ + A N+ G A + ++ VEE+ +G P+ + V G+ Sbjct: 388 IISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQAPKGTA----PTILSEMKPQQVVEGE 443 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589 V L V+G V WLK GK + D + E TL A +D Y CVA Sbjct: 444 DVMLACAVSGKPEPTVEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVAT 503 Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANA-----PPE-------IIEPLKDKIVAEG 4637 N+ G AE V P+ T A P + +I+ LKD V G Sbjct: 504 NALGSVSSSAELQVDEKPEISAPESTTPVAETALMSKPKDLEKTGAPVIKELKDTSVPIG 563 Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM--SRTADEYTLRISEAFPEDEGDYKC 4695 Q + ++ G P P V+W+K K+++ + F + ++L I + PED G YKC Sbjct: 564 QEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKC 623 Query: 4696 VAYNSAGRVTVAAKLKV-----TQPDQADNL------PALTPLR-------DIVVYEGQP 4737 +A+N G V A L + T P++ + LT + I V EG+ Sbjct: 624 IAFNEKGEVEAEANLSIKEETETAPEKVEPTADVGVKEELTAPKFMDKERGPIEVEEGED 683 Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797 + KT++ + +P I+WLR G ++ ++ + M VL + N EDT T+TC A Sbjct: 684 VRLKTRVRGQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARN 743 Query: 4798 AAGQVETSAKLVVKSK 4813 AG E +L+VK K Sbjct: 744 EAGMAEQDFELIVKFK 759 Score = 159 bits (385), Expect = 7e-38 Identities = 126/494 (25%), Positives = 211/494 (42%), Gaps = 28/494 (5%) Query: 4328 QTEEVTEQRVQKKVT--QKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITST 4385 + EE + R++ +V +P I V K +V + ++ V+ + + + T+T Sbjct: 677 EVEEGEDVRLKTRVRGQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTAT 736 Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKP----PIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441 T ++A E+ E VK P P + +QP V E + + + F E P Sbjct: 737 YTCVARNEAGMAEQDFELIVKFKAPAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPK 796 Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501 ++W + N +K S + + + L I+Q ED V+ V N GT A L V Sbjct: 797 VEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVR 856 Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561 V PSF + G R D KV G+ +V W K+ R + Sbjct: 857 VP--------VKPSFVTKLKPTEAVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFR 908 Query: 4562 ILEE-DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAAN 4620 E + ++L++ + DSG +C+A N AG+ A+ V K + A Sbjct: 909 FEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNV---------KERLFAPV 959 Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680 E P+K V EG+ I + KP V+W K K +K S + D + + Sbjct: 960 FEDEEQGPIK---VQEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNV 1016 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQ 4739 I A +D G+Y C A NS G+ + ++V + + P L +R + + EG+ A Sbjct: 1017 TIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAV 1076 Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799 ++T K +P+++WL++ +P ++ G A L + ED +TC A+ + Sbjct: 1077 MTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSL 1136 Query: 4800 GQVETSAKLVVKSK 4813 G V +SA+L V K Sbjct: 1137 GSVSSSAELQVDEK 1150 Score = 150 bits (364), Expect = 2e-35 Identities = 95/313 (30%), Positives = 151/313 (48%), Gaps = 18/313 (5%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT--YTL 4571 P F +++ +G+ +LD V+ +D W + + ++ R +++++G ++L Sbjct: 17 PVFKQPLKDIIAIAGEEAKLDVIVSVGAEVD--WYRGDQAIEDKGRFMLVDDEGEGMFSL 74 Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVS---LPATKDKPKPQT-------KAANA 4621 LI + P DSG YECVA N+AGE AE +V+ P ++K + +T K + Sbjct: 75 LIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASPVPEEKIQEETAPAVEAEKPSEV 134 Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 P I EPLK V EG CK G P PTV+W K + ++ + + ++ D + Sbjct: 135 APLITEPLKSLEVPEGATATLECKATGIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIV 194 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741 I +A D+G+YKC+ N G AKL V P + + + P I EG A+F Sbjct: 195 IKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVKPSFVKKMKPSEGI---EGGEARFD 251 Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTCRATTAAG 4800 QI KP ++W R I + F + G + L+I + ED G F C A+ AG Sbjct: 252 VQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQYSLVIIDLVTEDAGVFKCVASNEAG 311 Query: 4801 QVETSAKLVVKSK 4813 ++ A L VK + Sbjct: 312 KITARADLTVKER 324 Score = 148 bits (359), Expect = 9e-35 Identities = 113/416 (27%), Positives = 185/416 (44%), Gaps = 31/416 (7%) Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQ 4472 K+++ V ++A+ + G P P ++W+++ ++++ F + L+I Sbjct: 553 KELKDTSVPIGQEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDD 612 Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-----LTAQN----- 4522 V ED+ + +A N G + ANL ++E+ + P + LTA Sbjct: 613 VQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAPEKVEPTADVGVKEELTAPKFMDKE 672 Query: 4523 ---VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP- 4578 + V G+ VRL T+V G ++ WL+NG+ V+ N +E +L LE Sbjct: 673 RGPIEVEEGEDVRLKTRVRGQPEPEIEWLRNGEVVRKS-ENVNMESTAEQFVLALENVKV 731 Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638 +D+ Y CVA N AG A D E +V A A P+I+EP++ V E Q Sbjct: 732 EDTATYTCVARNEAGMAEQDFELIVKFKAP----------AGVAPQILEPIQPLEVGEDQ 781 Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698 ++ + + P V+W K + +K S + D TL I ++ ED+G Y+CV Sbjct: 782 IVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIR 841 Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758 N G V A L V P + + L P + EG A+F ++ KP ++W Sbjct: 842 NDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAV---EGGEARFDVKVKGSPKPEVEWFSGT 898 Query: 4759 ALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 I E F+ G L++ + D+GT C AT AG+V + A L VK + Sbjct: 899 TKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKER 954 Score = 146 bits (354), Expect = 4e-34 Identities = 107/426 (25%), Positives = 182/426 (42%), Gaps = 23/426 (5%) Query: 4391 EHKAQTQERVVEGPVKPSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449 E K Q + KPS+ P+ T+ ++ V E A E + G P P ++W ++N Sbjct: 115 EEKIQEETAPAVEAEKPSEVAPLITEPLKSLEVPEGATATLECKATGIPTPTVEWRKDNI 174 Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509 ++ + ++I+ D + + +N G +A L V Sbjct: 175 RVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVP------ 228 Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGT 4568 V PSF + G R D ++ G+ DV W + K+ R + E + Sbjct: 229 --VKPSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQ 286 Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628 Y+L+I++ +D+G ++CVA N AG+ A+ V K + A E + P Sbjct: 287 YSLVIIDLVTEDAGVFKCVASNEAGKITARADLTV---------KERQFAPIFEDEQMGP 337 Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688 + I+ +G + I KP P V WY K ++ + + D ++L I A E Sbjct: 338 V---ILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLE 394 Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSK 4747 D G+Y+C A+N G+ ++V + P L+ ++ V EG+ ++ K Sbjct: 395 DAGEYRCEAHNKLGKALRTYDVRVEEQAPKGTAPTILSEMKPQQVVEGEDVMLACAVSGK 454 Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807 +PT++WL+EG + + +E A L + ED +TC AT A G V +SA+ Sbjct: 455 PEPTVEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAE 514 Query: 4808 LVVKSK 4813 L V K Sbjct: 515 LQVDEK 520 Score = 136 bits (330), Expect = 3e-31 Identities = 127/520 (24%), Positives = 217/520 (41%), Gaps = 53/520 (10%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG+++ C V +PT +EW KPL + + ++ +L ED +Y Sbjct: 441 EGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALY 498 Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDT 2906 TC ATN+ GS ++S L+ + P+ A AE A ++K + + T Sbjct: 499 TCVATNALGSVSSSAELQVD---------EKPEISAPESTTPVAETALMSKPK--DLEKT 547 Query: 2907 EYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF 2966 P +I + + GQ L+ +V P+ +EW+ +GKV+E RF D Sbjct: 548 GAP----VIKELKDTSVPIGQEAKLDARVTGSPKPE--VEWFKDGKVVEDAGRFLYVEDE 601 Query: 2967 GFVTLDLV--DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEK 3024 LV DV D+G Y C A+N++GE + + ++ E T+ EK Sbjct: 602 EPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANL------SIKEETETAP-----EK 650 Query: 3025 IQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW 3084 ++ D KE + T P+F + +++ EG+ + + G IEW Sbjct: 651 VEPTADVGVKE------ELTA--PKFMDKERGPIEVEEGEDVRLKTRV--RGQPEPEIEW 700 Query: 3085 FYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS 3144 NG+ + S + VL + K D+ TY+C A N+ G AE +L K+ Sbjct: 701 LRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKA 760 Query: 3145 K-GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203 G P+ ++ I+ L+ G+ + T+ + K+EW N ++ S RIK+ +D Sbjct: 761 PAGVAPQI---LEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKAD 817 Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIREL 3263 L I ++ D G Y C N YG + A + ++P + K++ Sbjct: 818 NDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAML-------TVRVPVKPSFVTKLKPT 870 Query: 3264 ESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFE 3303 E+++G + + P + TK+ E FE Sbjct: 871 EAVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRFE 910 Score = 134 bits (325), Expect = 1e-30 Identities = 121/540 (22%), Positives = 224/540 (41%), Gaps = 47/540 (8%) Query: 72 PIFE-QIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PIFE + +G + +R P P V+W PL +R T ++ Sbjct: 328 PIFEDEQMGPVILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLA 387 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRHVSE---- 184 ++ ++ D GEY C A N+ G+A+ + V ++ + + V E Sbjct: 388 IISAKLE--DAGEYRCEAHNKLGKALRTYDVRVEEQAPKGTAPTILSEMKPQQVVEGEDV 445 Query: 185 TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRY 244 + G T E ++ + ++ + + TF+ L + + + Sbjct: 446 MLACAVSGKPEPTVEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNA 505 Query: 245 VGESDVQISTEIDR--------SLGPVSPPKIAQKPRN---------SKLQE-----GAD 282 +G ++D S PV+ + KP++ +L++ G + Sbjct: 506 LGSVSSSAELQVDEKPEISAPESTTPVAETALMSKPKDLEKTGAPVIKELKDTSVPIGQE 565 Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--TLRVRNTQKSDSGHYTLLA 340 A+ +++G+P+P V WFK+G+ + ++ + + +L + + Q D+G Y +A Sbjct: 566 AKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIA 625 Query: 341 ENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV-KVCQ 399 N G + L+++ TE T ++ E + + E+ AP+F+ K Sbjct: 626 FNEKGEVEAEANLSIKEETE-----------TAPEKVEPTADVGVKEELTAPKFMDKERG 674 Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 +V EG+ R RV G+P PE+ W N +R N + + + L + NV + D Sbjct: 675 PIEVEEGEDVRLKTRVRGQPEPEIEWLRNGEVVRKSENVN-MESTAEQFVLALENVKVED 733 Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTP 518 + TCVARN++G L V K VAP+ +E L V E + V L Sbjct: 734 TATYTCVARNEAGMAEQDFELIVKFKAPAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQ 793 Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 P++ W K+ + + + ++ D +TL I +++A D YQC +N G+ + A L Sbjct: 794 APKVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAML 853 Score = 124 bits (299), Expect = 2e-27 Identities = 105/365 (28%), Positives = 160/365 (43%), Gaps = 34/365 (9%) Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636 AP + +K ++ EG+ + + T VEW KPL S Sbjct: 427 APTILSEMKPQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIAT 484 Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696 L S ED YTC A NALG +S V K I S E P + +T+ Sbjct: 485 LTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEI---SAPESTTP----VAETAL 537 Query: 1697 YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756 + +D T APV +KD V Q A +AR+ G PK VEW ++G +E + Sbjct: 538 MSK--PKDLEKTGAPVIK-ELKDTSVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDA 592 Query: 1757 NRLTTMHDFG--YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814 R + D +L + V PED+G Y C A NE GE V+++A+L ++ + Sbjct: 593 GRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGE--------VEAEANLSIKEET 644 Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874 E+A +K++ D +E++ AP+F+ + GP ++ EG+ + R+ P+P Sbjct: 645 ETAPEKVEPTADVGV---KEELT-----APKFMDKERGPIEVEEGEDVRLKTRVRGQPEP 696 Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934 +EW NG+V++ + L + V ED+ YTC A N G A L Sbjct: 697 E--IEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFEL 754 Query: 1935 NVQSK 1939 V+ K Sbjct: 755 IVKFK 759 Score = 121 bits (292), Expect = 1e-26 Identities = 126/485 (25%), Positives = 194/485 (40%), Gaps = 66/485 (13%) Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 V W+ NGKP+++ D +L ++S ED+G Y C+A N+LG+A+ + +RV Sbjct: 360 VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRV- 418 Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463 E Q P G I+ E +KP + V+EG+ V Sbjct: 419 -------EEQAPKGTAPT-------------ILSE---MKP---------QQVVEGEDVM 446 Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523 C + + VEW K G+P++ RP ++ L ED +YTC A N Sbjct: 447 LACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATN 504 Query: 1524 LVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTS 1583 +G+ S L +I E L + K D T AP+ Sbjct: 505 ALGSVSSSAELQVDEKPEISAPESTTPVAET--ALMSKPK-------DLEKTGAPVIK-E 554 Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMS 1641 LK+ + GQ A + R+ +VEW+ + K ++ RF E +L I Sbjct: 555 LKDTSVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDD 612 Query: 1642 CLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHS 1701 PED+G Y C A N GE V ++ ++ ++ + E A ++ D Sbjct: 613 VQPEDAGKYKCIAFNEKGE--------VEAEANLSIKEETETAPEKVEPTADVGV----- 659 Query: 1702 AQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTT 1761 E +T I V E + + R+ G P+ +EWLRNG + S + Sbjct: 660 --KEELTAPKFMDKERGPIEVEEGEDVRLKTRVR--GQPEPEIEWLRNGEVVRKSENVNM 715 Query: 1762 MHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKI 1821 L ++ V ED+ TYTC A NE G A L V+ KA + Q +Q + Sbjct: 716 ESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKAPAGVAPQILEPIQPL 775 Query: 1822 QQLED 1826 + ED Sbjct: 776 EVGED 780 Score = 112 bits (269), Expect = 8e-24 Identities = 141/510 (27%), Positives = 204/510 (40%), Gaps = 84/510 (16%) Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466 R D +V+E + AP+F LR+G+ + + P+ V WY NGK L++ Sbjct: 316 RADLTVKERQF-APIFEDEQMGPVILRKGDELSIKETIRAKPKPD--VNWYHNGKPLRSA 372 Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPK 3526 L I ED+GEY C A+N G+A+ T ++V E Q PK Sbjct: 373 PTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRV--------EEQAPK 424 Query: 3527 GMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVND 3586 GT T+ E + P+ D++L+ S E P Sbjct: 425 ----------------GTAPTILSEMK----PQQVVEGEDVMLACAVSGKPE----PT-- 458 Query: 3587 SSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646 VEW GKPL S V+ + L D LYTC ATN G + S + Sbjct: 459 ----VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAE 514 Query: 3647 LQVKGRQGIILEPQLPSHFKSGTESIQKLEET--LHKREEITIEDEKPNPPRFTVEIKDN 3704 LQV + P++ S ES + ET + K +++ EK P E+KD Sbjct: 515 LQVDEK------PEI-----SAPESTTPVAETALMSKPKDL----EKTGAP-VIKELKDT 558 Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GFIALDIDYIYA 3762 VP G D RV G P ++WF +G+ R + D +L ID + Sbjct: 559 -SVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQP 615 Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822 DAG+Y C A N+ G A ++ + + E P G K +EL Sbjct: 616 EDAGKYKCIAFNEKGEVEAEANLSIKEETETAPEKVEPTADVGVK-EEL----------- 663 Query: 3823 EPIVSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881 T PKF+ + + VEE E VR + RV + +P+ IEW RNG+++ Sbjct: 664 -----TAPKFMDKERGPIEVEEGEDVRLKTRVRGQPEPE--IEWLRNGEVVRKSENVNME 716 Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 L + V ED+ Y C A N+ G Sbjct: 717 STAEQFVLALENVKVEDTATYTCVARNEAG 746 Score = 110 bits (264), Expect = 3e-23 Identities = 147/576 (25%), Positives = 227/576 (39%), Gaps = 80/576 (13%) Query: 1295 ARRTKQVR--EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP 1352 A RT VR E AP + + VEG +V L C + + T VEW GKP Sbjct: 410 ALRTYDVRVEEQAPKGTAPTILSEMKPQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKP 467 Query: 1353 IKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412 + RP YE + L S ED +YTC ATN LG +S L+V K ++ Sbjct: 468 LSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEI---- 523 Query: 1413 QHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVT 1472 S E + +T+ K +++ T P V + +V GQ + + VT Sbjct: 524 ---SAPESTTPVAETALMSKPKDLEK--TGAP--VIKELKDTSVPIGQEAKLDAR---VT 573 Query: 1473 DS-NLKVEWFKNGQPVTIGHRFRPIHDF--GYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529 S +VEWFK+G+ V RF + D +L I D+ ED+G Y C A N G E Sbjct: 574 GSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVE 633 Query: 1530 VSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEI 1589 L+ + T E E+++ D V E T +E+ Sbjct: 634 AEANLSIKEET--------ETAPEKVEPTADVG-------VKEELTAPKFMDKERGPIEV 678 Query: 1590 KEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGT 1649 +EG+ + R+ + ++EW N + ++ + L + + ED+ T Sbjct: 679 EEGEDVRLKTRVRGQPEP--EIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTAT 736 Query: 1650 YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQ 1709 YTC A N G A IV K G P++ LE + +D+++ Sbjct: 737 YTCVARNEAGMAEQDFELIVKFKAP-------AGVAPQI--LEPIQPLE--VGEDQIVKL 785 Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 FT QA PK+ EWL+N + ++ S R+ + D Sbjct: 786 TLTFT---------SEQA------------PKV--EWLKNNIRVKESYRIKSKADNDTAT 822 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829 L +K ED G Y C N+ G + + L V+ S + K++ E Sbjct: 823 LTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPVK-------PSFVTKLKPTEAVEG 875 Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYE 1865 + R DV+V + P + +G TK++E +E Sbjct: 876 GEARFDVKVKGSPKPE-VEWFSGTTKIAEKGRFRFE 910 Score = 109 bits (262), Expect = 5e-23 Identities = 97/413 (23%), Positives = 169/413 (40%), Gaps = 18/413 (4%) Query: 69 PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128 P P F K +GG A+F+ K++G+P P V W + E ++ E+ G+ Sbjct: 858 PVKPSFVTKLKPTEAVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRF---EEVGE 914 Query: 129 --VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE-- 184 SL++ + D G C A N+ G+ + + V E Sbjct: 915 EQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGE 974 Query: 185 --TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITK 242 +++ + + + + ++ D S DD T + + + Sbjct: 975 EISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEAT 1034 Query: 243 RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302 VG++ S E+++ + PK+ + R ++ EG DA +++G P P V W K+ Sbjct: 1035 NSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKD 1094 Query: 303 GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362 + L + + TL+++ D YT A N G + +S L V+ E Sbjct: 1095 DKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVD---EKG 1151 Query: 363 VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422 V + ++ E + E E +AP ++ D V G+ + D R+TG P PE Sbjct: 1152 VVPISPEPVSPV--FEEPVKAEPDEGTVAP-VIEGLNDVVVPLGREAKLDARITGSPKPE 1208 Query: 423 VTWFINDRQIRDDYNHKILV--NESGNHALMITNVTLSDSGVVTCVARNKSGE 473 V W I D Q+ +D + V E G +L+I +V D+G C+A N+ GE Sbjct: 1209 VEW-IKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 107 bits (257), Expect = 2e-22 Identities = 132/512 (25%), Positives = 203/512 (39%), Gaps = 82/512 (16%) Query: 917 DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTV 976 D++SIKE R +P D V W +G+P+ ++ + +L I S + Sbjct: 344 DELSIKE------TIRAKPKPD----VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKL 393 Query: 977 HDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEE 1036 DAG Y C A+N +G+A + D+ E Q P G T Sbjct: 394 EDAGEYRCEAHNKLGKA--------LRTYDVRVEEQAPKG----------------TAPT 429 Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096 + KP+ ++VEG+ V + + TVEW GK ++ + ++ + Sbjct: 430 ILSEMKPQ---------QVVEGEDVMLACAVSGKPE--PTVEWLKEGKPLSRDSHVRPKY 478 Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRH 1156 + L S ED +YT VA NA G SA + V+ + I E T Sbjct: 479 EAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAP-------ESTTP 531 Query: 1157 IEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHN 1216 + E+ + +E+ PV + P+ G+ L+ R+ G P VEWF + Sbjct: 532 VAETALMSKPKDLEK--TGAPVIKELKDTSVPI--GQEAKLDARV--TGSPKPEVEWFKD 585 Query: 1217 GRSVTVGSRFKTYYDF--GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274 G+ V RF D +L I D G+Y A N G A + + E Sbjct: 586 GKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKE--- 642 Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQF-SRALHNIETVEGTNVHLECR 1333 + E A E+++ D V+E++T AP+F + IE EG +V L+ R Sbjct: 643 -----ETETAPEKVEPTADVG-----VKEELT---APKFMDKERGPIEVEEGEDVRLKTR 689 Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393 ++ G +EW NG+ ++ + L L +V ED+ YTC A N+ G Sbjct: 690 VR--GQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGM 747 Query: 1394 AVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425 A L V K P LE IQ LE Sbjct: 748 AEQDFELIVKFKAP---AGVAPQILEPIQPLE 776 Score = 105 bits (253), Expect = 7e-22 Identities = 94/361 (26%), Positives = 154/361 (42%), Gaps = 40/361 (11%) Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840 ++ EG + ++ +PT VEW K+G+P++ S + + +L ED Sbjct: 438 QVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDE 495 Query: 841 GSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXX 900 YT A N LG S+A ++V + ++A PE + +T Sbjct: 496 ALYTCVATNALGSVSSSAELQVDEKPEISA----PESTTPVAETALMSKPKDL------- 544 Query: 901 XVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT 960 E T P K +KD S+ G A +AR+ G VEW KDG+ VE + R Sbjct: 545 ---EKTGAPVIKE-LKDT-SVPIGQEAKLDARVT--GSPKPEVEWFKDGKVVEDAGRFLY 597 Query: 961 FFNFG--YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLE 1018 + +L I V DAG Y C A+N G+ ANL+I + + E Sbjct: 598 VEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAP--------E 649 Query: 1019 KIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVE 1078 K++ D +EE+ P+F+ +G ++ EG+ + RV Q + +E Sbjct: 650 KVEPTADVG-----VKEEL---TAPKFMDKERGPIEVEEGEDVRLKTRVRGQPE--PEIE 699 Query: 1079 WYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 W NG+ + + + L + +V+ ED+ YT VARN AG A+ + V+ + Sbjct: 700 WLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFK 759 Query: 1139 S 1139 + Sbjct: 760 A 760 Score = 104 bits (250), Expect = 2e-21 Identities = 78/330 (23%), Positives = 141/330 (42%), Gaps = 36/330 (10%) Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304 + E D ++ + G P+I + + ++ E + + + P+V W KN Sbjct: 747 MAEQDFELIVKFKAPAGVA--PQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNI 804 Query: 305 RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364 R+ S + + ++ TL ++ ++ D G Y C++ + Y V S V Sbjct: 805 RVKESYRIKSKADNDTATLTIKQSRAEDQGVYQ--------CVIRNDYGTVHSEAMLTV- 855 Query: 365 DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424 R+ + P FV + + EG RFD +V G P PEV Sbjct: 856 -----------------RVPVK-----PSFVTKLKPTEAVEGGEARFDVKVKGSPKPEVE 893 Query: 425 WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484 WF +I + + +L++T++ L+DSG + C+A N++G+ + LNV Sbjct: 894 WFSGTTKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNV-- 951 Query: 485 KEQVVAPKFV-ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543 KE++ AP F E + V+EGE + + + P + W K+G P+ + ++ + + Sbjct: 952 KERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRD 1011 Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 + I AK D+ Y C A N G + Sbjct: 1012 DTHNVTIKTAKVDDSGEYTCEATNSVGKAS 1041 Score = 102 bits (244), Expect = 8e-21 Identities = 100/429 (23%), Positives = 171/429 (39%), Gaps = 46/429 (10%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141 + W++NGK + ++ + L I+ K D+G Y C A NK G+A + + Sbjct: 360 VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRVE 419 Query: 3142 DKS-KGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 +++ KG P + ++ + + +G+ C V P+ +EW G+P+ + ++ Sbjct: 420 EQAPKGTAPTILSEMKP-QQVVEGEDVMLACAVS--GKPEPTVEWLKEGKPLSRDSHVRP 476 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260 + L D Y C A N G + A + K E P+S + Sbjct: 477 KYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKP----EISAPESTTPV 532 Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320 E A P I +++D T + GQ A +AR+ P+ VEWF Sbjct: 533 AET-----ALMSKPKDLEKTGAPVIKELKD-TSVPIGQEAKLDARVTGSPKPE--VEWFK 584 Query: 3321 NGKKLPHGHRYRTFHD-----FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375 +GK + R+ D F +VI D+ E++G+Y+C+A N+ G +ANL Sbjct: 585 DGKVVEDAGRFLYVEDEEPEVFSLVIDDV---QPEDAGKYKCIAFNEKGEVEAEANLSIK 641 Query: 3376 SKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREG 3435 E+ +T + + D V+EE AP F + EG Sbjct: 642 -------------------EETETAPEKVEPTADVGVKEEL-TAPKFMDKERGPIEVEEG 681 Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLC 3495 E+ + R+ +P ++EW NG+ ++ +L + ED+ Y C Sbjct: 682 EDVRLKTRVRGQPEP--EIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTC 739 Query: 3496 RAYNNYGEA 3504 A N G A Sbjct: 740 VARNEAGMA 748 Score = 102 bits (244), Expect = 8e-21 Identities = 104/411 (25%), Positives = 172/411 (41%), Gaps = 37/411 (9%) Query: 1186 PPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSA 1245 P V EG+++ L C + +PT VEW G+ ++ S + Y+ L AT Sbjct: 436 PQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLE 493 Query: 1246 DTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDI 1305 D YT A N LGS +SA ++V E+ +I A E + + A +K +D+ Sbjct: 494 DEALYTCVATNALGSVSSSAELQVDEKPEI-------SAPESTTPVAETALMSKP--KDL 544 Query: 1306 TVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365 AP + L + G L+ R+ G VEWF +GK ++ RF + Sbjct: 545 EKTGAPVI-KELKDTSVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDE 601 Query: 1366 DYVALDLL--SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQY 1423 + L+ V PED+G Y C A N+ GE V A+ +L ++ + + EK++ Sbjct: 602 EPEVFSLVIDDVQPEDAGKYKCIAFNEKGE--------VEAEANLSIKEETETAPEKVEP 653 Query: 1424 LEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN 1483 D + E +T P+F+ + + V EG+ V + ++ + ++EW +N Sbjct: 654 TADVG-------VKEELTA-PKFMDKERGPIEVEEGEDVRLKTRVRGQPEP--EIEWLRN 703 Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543 G+ V L + ++ ED+ YTC A N G E L + Sbjct: 704 GEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKAPAG 763 Query: 1544 RSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594 + Q ++ ++V ED+ E QAP N+ +KE R Sbjct: 764 VAPQILEPIQPLEVGEDQIVKLTLTFTSE---QAPKVEWLKNNIRVKESYR 811 Score = 99.1 bits (236), Expect = 8e-20 Identities = 57/180 (31%), Positives = 88/180 (48%), Gaps = 3/180 (1%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P FVK + + EG RFD ++ G P P+V WF +I D + ++L+ Sbjct: 231 PSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQYSLV 290 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVL 510 I ++ D+GV CVA N++G+ + L V KE+ AP F E+ + +R+G+ + + Sbjct: 291 IIDLVTEDAGVFKCVASNEAGKITARADLTV--KERQFAPIFEDEQMGPVILRKGDELSI 348 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 P P + W +G P+ P L I + G +L I AK DA Y+C A N G Sbjct: 349 KETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLG 408 Score = 98.3 bits (234), Expect = 1e-19 Identities = 103/418 (24%), Positives = 164/418 (39%), Gaps = 39/418 (9%) Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287 + R+E + PK + P ++E++ V EG+ C V +P +E+ GK L Sbjct: 414 YDVRVEEQAPKGTAPTILSEMK-PQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSR 470 Query: 2288 AARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347 + ++ +L + ED Y+ A NALG +S+ + V K I + P Sbjct: 471 DSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISA----P 526 Query: 2348 EGLEKIRELE-SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDP 2406 E + E ++P + PV ++ + P+ GQ A D R+ G P Sbjct: 527 ESTTPVAETALMSKPKDLEKTGAPVIKELKDTSVPI--------GQEAKLDARV--TGSP 576 Query: 2407 TLKVEWFRNEKLIEDSSRITKTHDFG--YVSMTISHVRDEDEGVYMCRASNLLGEXXXXX 2464 +VEWF++ K++ED+ R D S+ I V+ ED G Y C A N GE Sbjct: 577 KPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGE----- 631 Query: 2465 XXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQ 2524 I+ ET+ +K+E + +E E P F GP E+ EG+ Sbjct: 632 -VEAEANLSIKEETETAP-----EKVEPTADVGVKE---ELTAPKFMDKERGPIEVEEGE 682 Query: 2525 HAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCK 2584 + RV G P EW NG ++ L + +V D Y C Sbjct: 683 DVRLKTRV--RGQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCV 740 Query: 2585 AINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAP 2642 A N AG + P+ E IQ E +++ ++ + +QAP Sbjct: 741 ARNEAGMAEQDFELIVKFKA---PAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAP 795 Score = 95.1 bits (226), Expect = 1e-18 Identities = 100/390 (25%), Positives = 150/390 (38%), Gaps = 34/390 (8%) Query: 1807 SLQLESQHESALQKIQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYE 1865 S +LE E + +L + R Y R + + AP ++++ P ++ EG+ Sbjct: 390 SAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQAPKGTAPTILSEMK-PQQVVEGEDVMLA 448 Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925 C + P+P VEW GK L R + A L + ED YTC A N L Sbjct: 449 CAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNAL 506 Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIK 1985 G SS L V K I E S+ K + + V+ K +K Sbjct: 507 GSVSSSAELQVDEKPEISAPESTTPVAETALM----SKPKDLEKTGAPVI------KELK 556 Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF--GYVALDILYAY 2043 + V G L+A +T P VEW+ +G+ V+ RF D +L I Sbjct: 557 DTSVPIGQEAKLDARVT--GSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQ 614 Query: 2044 AEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEE 2103 ED G Y C A N GE V+A++ L + E +K++ ++EE Sbjct: 615 PEDAGKYKCIAFNEKGE--------VEAEANLSIKEETETAPEKVEPTADV----GVKEE 662 Query: 2104 QPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD 2163 P F+ ++EG+ + RV P I+W NG+ +R Sbjct: 663 LTA--PKFMDKERGPIEVEEGEDVRLKTRVR--GQPEPEIEWLRNGEVVRKSENVNMEST 718 Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEA 2193 L + ED+ TY C A N+ G A Sbjct: 719 AEQFVLALENVKVEDTATYTCVARNEAGMA 748 Score = 94.3 bits (224), Expect = 2e-18 Identities = 100/390 (25%), Positives = 159/390 (40%), Gaps = 43/390 (11%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P + +K +EG + + +PT +EWLK G+ + S + +L Sbjct: 428 PTILSEMKPQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATL 485 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756 S ++D YTC A +A G + A L V + I PE+ + + SK Sbjct: 486 TFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISA----PESTTPVAETALMSK- 540 Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816 + +E+ + I+ L+D + G+ A +A++T P VEW+KDG+ + + Sbjct: 541 --PKDLEKTGA---PVIKELKDT-SVPIGQEAKLDARVT--GSPKPEVEWFKDGKVVEDA 592 Query: 817 SRITSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874 R + + SL I ++ EDAG Y A N+ GE + A++ + T TA Sbjct: 593 GRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSI-KEETETA---- 647 Query: 875 PEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLE 934 PE+ +E T V E P+F + I ++EG + R+ Sbjct: 648 PEK---VEPT-------------ADVGVKEELTAPKFMDKERGPIEVEEGEDVRLKTRVR 691 Query: 935 PIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQAT 994 G +EWL++G V S + L +++V V D YTC A N G A Sbjct: 692 --GQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAE 749 Query: 995 TSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024 L + K P LE IQ LE Sbjct: 750 QDFELIVKFK---APAGVAPQILEPIQPLE 776 Score = 90.2 bits (214), Expect = 4e-17 Identities = 120/538 (22%), Positives = 204/538 (37%), Gaps = 72/538 (13%) Query: 66 PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125 P +P I E I + + K P V W + + E Y ++ Sbjct: 761 PAGVAPQILEPI-QPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKE--SYRIKSKAD 817 Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYG----EAICSVYIQPEGXXXXXXXXXXXXXYRH 181 +L IKQ D+G Y C RN YG EA+ +V + + Sbjct: 818 NDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAVEGGE 877 Query: 182 VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241 V+ K G+ E T K+A + + F +L ++ +S T Sbjct: 878 ARFDVKVK--GSPKPEVEWFSGTTKIAEKGRFRFEEVGE---EQFSL-VLTDLQLTDSGT 931 Query: 242 KRYVGESDV-QISTEIDRSLGP--VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT 298 + + ++ ++++ D ++ +P ++ K+QEG + + + P+ V Sbjct: 932 IKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPKADVK 991 Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 W KNG+ L +S+K ++ + + + ++ + DSG YT A N G Sbjct: 992 WMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVG------------- 1038 Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418 + T E E+++ K AP+ + + + EG+ C VTG+ Sbjct: 1039 -----------KASRTYSVEVEKKVP---KGHAPKLIAEMRPMQIIEGEDAVMTCEVTGK 1084 Query: 419 PYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQ 477 P P V W +D+ + D + N G A L + L D + TC A N G + Sbjct: 1085 PEPSVEWLKDDKPLPRDQRLTPMYN--GEVATLKLQKAILEDEALYTCTASNSLGSVSSS 1142 Query: 478 CRLNVIEKEQV------VAPKF----------------VERFSTLNVREGEPVVLNARAV 515 L V EK V V+P F +E + + V G L+AR Sbjct: 1143 AELQVDEKGVVPISPEPVSPVFEEPVKAEPDEGTVAPVIEGLNDVVVPLGREAKLDARIT 1202 Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDG---GASTLDIPRAKASDAAWYQCTAQNVAG 570 G+P P + W KDG ++ + ++ + G +L I + DA Y+C A N G Sbjct: 1203 GSPKPEVEWIKDG-QVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKG 1259 Score = 89.8 bits (213), Expect = 5e-17 Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 3/198 (1%) Query: 383 IEISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441 + + E+ AP F Q V EG+ V +P +V W N + ++D + Sbjct: 949 LNVKERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVR 1008 Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK-EQVVAPKFVERFSTL 500 + H + I + DSG TC A N G+ + + V +K + APK + + Sbjct: 1009 SRDD-THNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPM 1067 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 + EGE V+ G P P + W KD P+ + L +G +TL + +A D A Sbjct: 1068 QIIEGEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEAL 1127 Query: 561 YQCTAQNVAGSTATRARL 578 Y CTA N GS ++ A L Sbjct: 1128 YTCTASNSLGSVSSSAEL 1145 Score = 89.4 bits (212), Expect = 6e-17 Identities = 91/385 (23%), Positives = 157/385 (40%), Gaps = 35/385 (9%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P +K +V EG V L ++ +PT VEW G+P+ + + Y+ L Sbjct: 428 PTILSEMKPQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATL 485 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097 A ED Y C ATNA+G +++ ++VD K + + + E +P Sbjct: 486 TFKSATLEDEALYTCVATNALGSVSSSAELQVDEKP----EISAPESTTPVAETALMSKP 541 Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157 K +E+ PV + ++ G A + RV P ++WF +G+ + R Sbjct: 542 KDLEKT---GAPVIKELKDT--SVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGR 594 Query: 2158 YRTTHDF--GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN 2215 + D +L I ED+G Y C A N+ GE V N+ + + Sbjct: 595 FLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGE--------VEAEANLSIKEETET 646 Query: 2216 GLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLR 2275 EK+ + + V+E +++ P+F+ + RG V EG+ + +V +P Sbjct: 647 APEKVEP------TADVGVKE-ELTAPKFMDKERGPIEVEEGEDVRLKTRVRGQPEP--E 697 Query: 2276 IEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335 IE+ NG+ ++ + ++ L +++ ED Y+ A N G + V Sbjct: 698 IEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVK 757 Query: 2336 AKGSIISESQRPEGLEKIRELESAE 2360 K P+ LE I+ LE E Sbjct: 758 FKA---PAGVAPQILEPIQPLEVGE 779 Score = 87.0 bits (206), Expect = 3e-16 Identities = 113/460 (24%), Positives = 176/460 (38%), Gaps = 72/460 (15%) Query: 2272 PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS 2331 P + +YHNGK L+SA I SL I EDAGEY +A N LG Sbjct: 356 PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYD 415 Query: 2332 MTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEG 2391 + V E Q P+G P ++ +P + EG Sbjct: 416 VRV--------EEQAPKG----------------TAPTILSEMKP---------QQVVEG 442 Query: 2392 QTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMC 2451 + C + +PT VEW + K + S + ++ ++T EDE +Y C Sbjct: 443 EDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTC 500 Query: 2452 RASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFT 2511 A+N LG + E PE + + + + E + P+ Sbjct: 501 VATNALGSVSSSAELQVDE----KPEISAPESTTPVAETALMSKPKDLE---KTGAPVIK 553 Query: 2512 QVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF--GFVTLD 2569 ++ + GQ A +ARV G P EW+ +G ++ RF D +L Sbjct: 554 ELKDTSVPI--GQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLV 609 Query: 2570 INSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKV 2629 I+ V DAG Y C A N G + +++ E+ E A KV Sbjct: 610 IDDVQPEDAGKYKCIAFNEKGEVEAEA-----------NLSIKEET-------ETAPEKV 651 Query: 2630 PEMFVDTGVQQ---APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLT 2686 E D GV++ AP F + ++ EG+ V L+ +V R P +IEW +NG + Sbjct: 652 -EPTADVGVKEELTAPKFMDKERGPIEVEEGEDVRLKTRV--RGQPEPEIEWLRNGEVVR 708 Query: 2687 TGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726 + L++ +++ +D+ YTC A N G A Sbjct: 709 KSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMA 748 Score = 87.0 bits (206), Expect = 3e-16 Identities = 72/318 (22%), Positives = 126/318 (39%), Gaps = 33/318 (10%) Query: 263 VSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321 ++ PK K R +++EG D + + ++ G P P + W +NG+ + S + +T Sbjct: 663 LTAPKFMDKERGPIEVEEGEDVRLKTRVRGQPEPEIEWLRNGEVVRKSENVNMESTAEQF 722 Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381 L + N + D+ YT C+ + E+ + +Q + I + Sbjct: 723 VLALENVKVEDTATYT--------CVARN---------EAGMAEQDFELIVKFK------ 759 Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441 + +APQ ++ Q +V E ++ + T P+V W N+ ++++ Y K Sbjct: 760 ----APAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSK 815 Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501 ++ L I D GV CV RN G + L V V P FV + Sbjct: 816 A-DNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV---RVPVKPSFVTKLKPTE 871 Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS-TLDIPRAKASDAAW 560 EG + + G+P P + W I R G +L + + +D+ Sbjct: 872 AVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGT 931 Query: 561 YQCTAQNVAGSTATRARL 578 +C A N AG +RA L Sbjct: 932 IKCIATNEAGKVTSRADL 949 Score = 86.2 bits (204), Expect = 6e-16 Identities = 78/333 (23%), Positives = 136/333 (40%), Gaps = 21/333 (6%) Query: 252 ISTEIDRSLGPVSPPKIAQKPRNSKLQ-EGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310 + +I+ + P S + ++P + G +A+ V +S V W++ Q + + Sbjct: 2 VPQKIEDTTAPDSKAPVFKQPLKDIIAIAGEEAKLDVIVSVGAE--VDWYRGDQAIEDKG 59 Query: 311 KHEIITTHNHT--TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368 + ++ +L + + Q SDSG Y +A N G V S E V D S Sbjct: 60 RFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAG--------EVSSKAELIVNDGAS 111 Query: 369 QYITDTQQRETEERIEISEKA-LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427 + Q ET +E + + +AP + + +V EG +C+ TG P P V W Sbjct: 112 PVPEEKIQEETAPAVEAEKPSEVAPLITEPLKSLEVPEGATATLECKATGIPTPTVEWRK 171 Query: 428 NDRQIRDDYNHKILVNESGNH-ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486 ++ ++R+ +I + G+ ++I + +D G C+ +N G +L V Sbjct: 172 DNIRVRE--GRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV---N 226 Query: 487 QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG-GA 545 V P FV++ EG + + G+P P + W + I + G Sbjct: 227 VPVKPSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQ 286 Query: 546 STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 +L I DA ++C A N AG RA L Sbjct: 287 YSLVIIDLVTEDAGVFKCVASNEAGKITARADL 319 Score = 85.4 bits (202), Expect = 1e-15 Identities = 87/362 (24%), Positives = 142/362 (39%), Gaps = 36/362 (9%) Query: 2100 IEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158 +EE+ P G P L+ + + + EG+ C V P T++W G+ + Sbjct: 418 VEEQAPKGTAPTILSEMKP-QQVVEGEDVMLACAVS--GKPEPTVEWLKEGKPLSRDSHV 474 Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLE 2218 R ++ L ED Y C ATN LG ++ L+V I P Sbjct: 475 RPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEI----SAPESTT 530 Query: 2219 KIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEF 2278 + + +E K P + EL+ T+ V G+ A + +V P +E+ Sbjct: 531 PVAETALMSKPKDLE----KTGAP-VIKELKDTS-VPIGQEAKLDARV--TGSPKPEVEW 582 Query: 2279 YHNGKALQSAARFHITFDFG--YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336 + +GK ++ A RF D SL I PEDAG+Y A N G V A Sbjct: 583 FKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGE--------VEA 634 Query: 2337 KGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHF 2396 + ++ + + EK+ EP + E +T P F + ++EG+ Sbjct: 635 EANLSIKEETETAPEKV------EPTADVGVKEELTA--PKFMDKERGPIEVEEGEDVRL 686 Query: 2397 DCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNL 2456 R+ G P ++EW RN +++ S + + + +V+ ED Y C A N Sbjct: 687 KTRVR--GQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNE 744 Query: 2457 LG 2458 G Sbjct: 745 AG 746 Score = 85.0 bits (201), Expect = 1e-15 Identities = 126/523 (24%), Positives = 190/523 (36%), Gaps = 82/523 (15%) Query: 3405 VRRKDTSVEEE--KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKS 3462 +R D VEE+ KG AP + + + EGE+ ++ +P VEW GK Sbjct: 411 LRTYDVRVEEQAPKGTAPTILSEMKP-QQVVEGEDVMLACAVSGKPEPT--VEWLKEGKP 467 Query: 3463 LKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIIL-E 3521 L S R + L ED Y C A N G ++A ++V K I E Sbjct: 468 LSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPE 527 Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL 3581 S P + K LE ++G P D + A + R+ Sbjct: 528 STTPVAETALMSKPKDLE-------------KTGAP--VIKELKDTSVPIGQEAKLDARV 572 Query: 3582 IPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI--LEIGGVYQRDAGLYTCKATNRHG 3639 VEWF +GK + R + D + L I V DAG Y C A N G Sbjct: 573 --TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKG 630 Query: 3640 EATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTV 3699 E L +K E + E + ++ +++E P+F Sbjct: 631 EVEAEANLSIK-------------------EETETAPEKVEPTADVGVKEEL-TAPKFMD 670 Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759 + + I+V EG V RV G P I+W NG V+ + L ++ Sbjct: 671 KERGPIEVEEGEDVRLKTRVR--GQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALEN 728 Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819 + D YTC A N+ G A ++ K + Q+ E I+ LE G Sbjct: 729 VKVEDTATYTCVARNEAGMAEQDFELIVKFKAPAGVAPQIL-----EPIQPLEVG----- 778 Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879 E+ IV F T E++ PK +EW +N + +R + Sbjct: 779 --EDQIVKLTLTF-------TSEQA----------PK------VEWLKNNIRVKESYRIK 813 Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922 + D +L I AED G Y C ND+G ++A ++ + Sbjct: 814 SKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVR 856 Score = 83.4 bits (197), Expect = 4e-15 Identities = 95/408 (23%), Positives = 165/408 (40%), Gaps = 51/408 (12%) Query: 3670 ESIQKLEETLHKREEITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTM 3727 E+ KL + L + ++ +E++ P P E+K V EG V C V +PT Sbjct: 402 EAHNKLGKAL-RTYDVRVEEQAPKGTAPTILSEMKPQ-QVVEGEDVMLACAVSGKPEPT- 458 Query: 3728 RIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC 3787 ++W G+P + S V + L D YTC ATN GS +++A++ Sbjct: 459 -VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQV 517 Query: 3788 SAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGV 3847 K P+ + E + + PK+ + T I ++K +V + Sbjct: 518 DEK---------PEISAPESTTPVAETALMSKPKD--LEKTGAPVIKELKDTSVPIGQEA 566 Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD--MGFVSLDILYVYAEDSGEYICR 3905 + + RV PK +EW+++GK++ R+ V D SL I V ED+G+Y C Sbjct: 567 KLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCI 624 Query: 3906 AVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLY 3965 A N+ GE +A +S K+ + + P T++V + E+ Sbjct: 625 AFNEKGEVEAEANLSIKEETETAPEKVEP-------------------TADVGVKEE--- 662 Query: 3966 DVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPI 4025 P+F+ + + + E E + + ++ G P ++EW NG+ + Sbjct: 663 ----LTAPKFMDKERGPIEVEEGEDVRLKTRVR--GQPEPEIEWLRNGEVVRKSENVNME 716 Query: 4026 YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDET--KAVIKTTGKPGI 4071 + V ED+ Y C A N GM E + ++K G+ Sbjct: 717 STAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKAPAGV 764 Score = 82.6 bits (195), Expect = 7e-15 Identities = 71/286 (24%), Positives = 125/286 (43%), Gaps = 19/286 (6%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141 ++W NGK ++ S ++ + I K DSG Y+C ATN G+A + +E Sbjct: 990 VKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVE 1049 Query: 3142 DK-SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 K KG P+ ++ ++ + +G+ A C V P+ +EW + +P+ R+ Sbjct: 1050 KKVPKGHAPKLIAEMRPMQ-IIEGEDAVMTCEV--TGKPEPSVEWLKDDKPLPRDQRLTP 1106 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260 + + L + D Y C A N G + A + KG V + P+ ++ + Sbjct: 1107 MYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVV---PISPEPVSPV 1163 Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320 E E ++ + P I + DV + G+ A +AR+ P +VEW Sbjct: 1164 FE-EPVKAEPDEGTVAP------VIEGLNDVV-VPLGREAKLDARI--TGSPKPEVEWIK 1213 Query: 3321 NGKKLPHGHR--YRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364 +G+ + R Y + GI L I E++G+Y+C+A N+ G Sbjct: 1214 DGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKG 1259 Score = 82.2 bits (194), Expect = 9e-15 Identities = 107/462 (23%), Positives = 184/462 (39%), Gaps = 68/462 (14%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA----F 3103 P F T K + EG A ++ + G +EWF I R R F Sbjct: 861 PSFVTKLKP-TEAVEGGEARFDVKV--KGSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQF 917 Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 +V+ ++ + TDSGT C ATN+ G +++ + + K + P F Q +++ Sbjct: 918 SLVLTDL---QLTDSGTIKCIATNEAG--KVTSRADLNVKERLFAPVFEDEEQGPIKVQE 972 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G+ + V P ++W NG+P++ S+++ S + I + DSGEY Sbjct: 973 GEEISIKSVVKA--KPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYT 1030 Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPK 3283 C A N G+ ++ K + P +A++R ++ ++G + +P Sbjct: 1031 CEATNSVGKASRTYSVEVEKK---VPKGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEP 1087 Query: 3284 FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343 + ++D L Q RL P+ YNG+ + L Sbjct: 1088 SVEWLKDDKPLPRDQ------RLTPM----------YNGE---------------VATLK 1116 Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDS 3403 + E+ Y C A+N LG S+ A L+ K G+ + S Sbjct: 1117 LQKAILEDEALYTCTASNSLGSVSSSAELQVDEK---------------GVVPISPEPVS 1161 Query: 3404 MVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL 3463 V + E ++G L+++ + G A +AR+T + P +VEW +G+ + Sbjct: 1162 PVFEEPVKAEPDEGTVAPVIEGLNDVV-VPLGREAKLDARITGSPKP--EVEWIKDGQVV 1218 Query: 3464 KAGSRFRTF--CDFGFVILEISPTYPEDSGEYLCRAYNNYGE 3503 + RF + G L I PED+G+Y C A+N GE Sbjct: 1219 EDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 80.6 bits (190), Expect = 3e-14 Identities = 80/302 (26%), Positives = 128/302 (42%), Gaps = 33/302 (10%) Query: 2944 KIEWYFNGKVLEQGSRFKLTSDFG--FVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001 +++WY + +E RF L D G +L + DV DSG+Y C A+N GE Sbjct: 45 EVDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEV------ 98 Query: 3002 YCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDIS 3061 +SK LI E EKIQ E++ ++P + P T K + ++ Sbjct: 99 --SSKAELIVNDGASPVPE--EKIQ--EETAPAVEAEKPSEVA---PLITEPLKSL-EVP 148 Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121 EG A E TG + +EW + + RI+T + + I TD G Y Sbjct: 149 EGATATLECKA--TGIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEY 206 Query: 3122 SCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181 C N +G + KL + KP F ++ EG++ G+ A F+ + PD Sbjct: 207 KCMVKNDFGLDYTTAKLTV---NVPVKPSFVKKMKPSEGIEGGE-ARFDVQIKGSPKPD- 261 Query: 3182 KIEWYHNGQPMRHSTRI---KTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237 +EW+ + R +T D + V++D+ D+G + C A N+ G+ RA Sbjct: 262 -VEWFRGMTKITDKERFHVEETGEDQYSLVIIDLV---TEDAGVFKCVASNEAGKITARA 317 Query: 3238 TI 3239 + Sbjct: 318 DL 319 Score = 79.8 bits (188), Expect = 5e-14 Identities = 67/234 (28%), Positives = 113/234 (48%), Gaps = 19/234 (8%) Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287 +S +E + PK P+ + E+R + EG+ A C+V +P+ +E+ + K L Sbjct: 1044 YSVEVEKKVPKGHAPKLIAEMR-PMQIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPR 1100 Query: 2288 AARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347 R ++ +L +Q + ED Y+ A N+LG +S+ + V KG ++ S P Sbjct: 1101 DQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKG-VVPIS--P 1157 Query: 2348 EGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPT 2407 E + + E EP K P+ T PV + L ++ + G+ A D R+ G P Sbjct: 1158 EPVSPVFE----EPVKAE--PDEGT-VAPVI-EGLNDVV-VPLGREAKLDARI--TGSPK 1206 Query: 2408 LKVEWFRNEKLIEDSSRI--TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 +VEW ++ +++ED+ R + + G S+ I V+ ED G Y C A N GE Sbjct: 1207 PEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 79.8 bits (188), Expect = 5e-14 Identities = 64/219 (29%), Positives = 99/219 (45%), Gaps = 17/219 (7%) Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636 AP ++ ++I EG+ A + + + VEW ++KPL R T N Sbjct: 1057 APKLIAEMRPMQIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVAT 1114 Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696 L + + ED YTC A N+LG +S V K + + + P E+ K Sbjct: 1115 LKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPE-----PVSPVFEEPVK 1169 Query: 1697 YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756 A+ + T APV + D+ V + A +AR+ G PK VEW+++G +E + Sbjct: 1170 -----AEPDEGTVAPVIE-GLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDA 1221 Query: 1757 NRLTTM--HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793 R + + G +L + V PED+G Y C A NE GE Sbjct: 1222 GRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 79.4 bits (187), Expect = 7e-14 Identities = 72/293 (24%), Positives = 121/293 (41%), Gaps = 28/293 (9%) Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNF 1632 ++AP+ LK++ G+ A +L + +V+WY ++ ++ RF + Sbjct: 14 SKAPVFKQPLKDIIAIAGEEA----KLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGE 69 Query: 1633 GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLE 1692 G +L I P DSG Y C A N GE + IV+ S +P E Sbjct: 70 GMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGAS---------PVPEEKIQE 120 Query: 1693 DTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVP 1752 +T+ EV AP+ T P+K + V E A E + G P VEW ++ + Sbjct: 121 ETAPAVEAEKPSEV---APLITEPLKSLEVPEGATATLECKA--TGIPTPTVEWRKDNIR 175 Query: 1753 IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812 + R+ T D + + +K D G Y C N+ G T++ L V Sbjct: 176 VREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVK----- 230 Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYE 1865 S ++K++ E + R DV++ + P + G TK+++ + H E Sbjct: 231 --PSFVKKMKPSEGIEGGEARFDVQIKGSPKPD-VEWFRGMTKITDKERFHVE 280 Score = 79.4 bits (187), Expect = 7e-14 Identities = 80/290 (27%), Positives = 122/290 (42%), Gaps = 30/290 (10%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P F +P+K+ G EA L + V+WY + ++ RF D G Sbjct: 17 PVFKQPLKDIIAIAGE----EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGMF 72 Query: 2038 DILY--AYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 +L D+G Y C A N GE + + + V+ D +KIQE E Sbjct: 73 SLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVN-------DGASPVPEEKIQE----E 121 Query: 2096 RPKPIEEEQPGQ-RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154 +E E+P + P+ L SLE + EG A EC+ I P T++W + ++R Sbjct: 122 TAPAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKATGIPTP--TVEWRKDNIRVRE 178 Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214 G R +TT D + + I D G Y C N G T L V N+ + P Sbjct: 179 GRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV----NVPV---KP 231 Query: 2215 NGLEKIRQLEA-QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFE 2263 + ++K++ E +G R +V + K SP V RG T + + + H E Sbjct: 232 SFVKKMKPSEGIEGGEARFDV-QIKGSPKPDVEWFRGMTKITDKERFHVE 280 Score = 79.0 bits (186), Expect = 9e-14 Identities = 70/242 (28%), Positives = 104/242 (42%), Gaps = 21/242 (8%) Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890 Q+ ED ++AP F L ++ G+ E +++ V+WY + ++ Sbjct: 4 QKIEDTTAPDSKAPVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAIEDK 58 Query: 1891 HRYRTSNDFGFAALDILT--VYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948 R+ +D G +L V DSG Y C A NN G+ S L I+ D Sbjct: 59 GRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGAS 111 Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008 EKIQ E+ + AV+ + P +P+K+ EV EG LE T + PT Sbjct: 112 PVPEEKIQ--EETAP---AVEAEKPSEVAPLITEPLKSLEVPEGATATLECKATGIPTPT 166 Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068 VEW + V++G R KTT D + + I A D G Y C N G TT+ + Sbjct: 167 --VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLT 224 Query: 2069 VD 2070 V+ Sbjct: 225 VN 226 Score = 79.0 bits (186), Expect = 9e-14 Identities = 84/379 (22%), Positives = 140/379 (36%), Gaps = 33/379 (8%) Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443 E + K AP + + + V EG+ C V+G+P P V W + + D +H Sbjct: 420 EQAPKGTAPTILSEMKPQQVVEGEDVMLACAVSGKPEPTVEWLKEGKPLSRD-SHVRPKY 478 Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV- 502 E+ L + TL D + TCVA N G + L V EK ++ AP+ + + Sbjct: 479 EAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALM 538 Query: 503 -------REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR--- 552 + G PV+ + P + V P PE+ DG D R Sbjct: 539 SKPKDLEKTGAPVIKELKDTSVPIGQEAKLDARVTGSPKPEVEWFKDGKVVE-DAGRFLY 597 Query: 553 AKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXX 612 + + + +V A + + + L + T+ Sbjct: 598 VEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAP--------- 648 Query: 613 XYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEW 672 E+ P G ++ + P + EG + +TR+ G P +IEW Sbjct: 649 ------EKVEPTADVGVKEELTAPKFMDKERGPIEVEEGEDVRLKTRVR--GQPEPEIEW 700 Query: 673 LKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732 L+NG+ + S L + ++ ++D+ YTC A + G+AE L V +A Sbjct: 701 LRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKA 760 Query: 733 TIERTSQHPETLQYIQQLE 751 P+ L+ IQ LE Sbjct: 761 P---AGVAPQILEPIQPLE 776 Score = 77.4 bits (182), Expect = 3e-13 Identities = 90/357 (25%), Positives = 146/357 (40%), Gaps = 47/357 (13%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 Q+VEG+ + L V K +P +EW GK L + S + + TL D Sbjct: 438 QVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDE 495 Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD 3041 +YTC A N G +S+ + K + P+ T + E +L +P Sbjct: 496 ALYTCVATNALGSVSSSAELQVDEKPEI----SAPESTTPVA-----ETALMSKPKDL-- 544 Query: 3042 DDTGRPPEFTTVFKDIVDISE--GQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRT 3099 + TG P V K++ D S GQ A +A + TG +EWF +GK +E + R Sbjct: 545 EKTGAP-----VIKELKDTSVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLY 597 Query: 3100 VYAFGMVVLEIL--GTKTTDSGTYSCRATNKWGQAEISVKLECVDKSK------------ 3145 V V ++ + D+G Y C A N+ G+ E L ++++ Sbjct: 598 VEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAPEKVEPTADV 657 Query: 3146 GQK-----PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 G K P+F + +++G+ + V P+ +IEW NG+ +R S + Sbjct: 658 GVKEELTAPKFMDKERGPIEVEEGEDVRLKTRV--RGQPEPEIEWLRNGEVVRKSENVNM 715 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG---EDFTRATINCYGKGGVYLESLQP 3254 S VL + + D+ Y C A N+ G +DF + GV + L+P Sbjct: 716 ESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDF-ELIVKFKAPAGVAPQILEP 771 Score = 76.6 bits (180), Expect = 5e-13 Identities = 86/361 (23%), Positives = 148/361 (40%), Gaps = 52/361 (14%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 + V+E ++ P F E +G V EG+ + V+ P +++ NGK L+ +++ Sbjct: 949 LNVKE-RLFAPVFEDEEQGPIKVQEGEEISIKSVVKA--KPKADVKWMKNGKPLKDSSKV 1005 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 + ++ I+ +D+GEY+ +A N++G + S+ V E + P+G Sbjct: 1006 DVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEV--------EKKVPKG-- 1055 Query: 2352 KIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVE 2411 P+ + RP+ I EG+ A C + G P VE Sbjct: 1056 --------------HAPKLIAEMRPM---------QIIEGEDAVMTCEV--TGKPEPSVE 1090 Query: 2412 WFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXX 2471 W +++K + R+T ++ ++ + EDE +Y C ASN LG Sbjct: 1091 WLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEK 1150 Query: 2472 XXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEAR 2531 + + PE + + E+P + EPD P+ + L G+ A +AR Sbjct: 1151 GVVPIS---PEPVSPV--FEEPVK---AEPDEGTVAPVIEGLNDVVVPL--GREAKLDAR 1200 Query: 2532 VVPVGDPSLRFEWYINGVELKMGSRFR--TTHDFGFVTLDINSVVANDAGLYMCKAINRA 2589 + G P EW +G ++ RF + G +L I+ V DAG Y C A N Sbjct: 1201 I--TGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEK 1258 Query: 2590 G 2590 G Sbjct: 1259 G 1259 Score = 75.4 bits (177), Expect = 1e-12 Identities = 89/378 (23%), Positives = 138/378 (36%), Gaps = 33/378 (8%) Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLR 2541 E K+ K + ++ R EE + P + P ++ EG+ V G P Sbjct: 402 EAHNKLGKALRTYDVRVEEQAPKGTAPTILSEMK-PQQVVEGEDVMLACAVS--GKPEPT 458 Query: 2542 FEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXX 2601 EW G L S R ++ TL S D LY C A N G Sbjct: 459 VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVD 518 Query: 2602 XXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVY 2661 I PES + E A+ P+ TG AP+ LK + GQ Sbjct: 519 EKPEI----SAPESTTPV--AETALMSKPKDLEKTG---APVI-KELKDTSVPI-GQEAK 567 Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDDSGIYTCKA 2719 L+A+V P ++EWFK+G + R D + +L I+ ++ +D+G Y C A Sbjct: 568 LDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIA 625 Query: 2720 TNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISH 2779 N GE + A++ I++ E + P + +G Sbjct: 626 FNEKGEVEAEANLSIKEETETAPEKVEPTA--DVGV-----------KEELTAPKFMDKE 672 Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839 I +EG+++ + V +P +IEW N + + L + + Sbjct: 673 RGPIEVEEGEDVRLKTRVRGQPEP--EIEWLRNGEVVRKSENVNMESTAEQFVLALENVK 730 Query: 2840 EEDSGIYTCKATNSKGSA 2857 ED+ YTC A N G A Sbjct: 731 VEDTATYTCVARNEAGMA 748 Score = 75.4 bits (177), Expect = 1e-12 Identities = 62/220 (28%), Positives = 98/220 (44%), Gaps = 18/220 (8%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP M+ +++ E + A + G P+ VEWL++ P+ RLT M++ Sbjct: 1057 APKLIAEMRPMQIIEGEDAVMTCEV--TGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVAT 1114 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829 L ++ ED YTC A N LG +S+ L V K + + + S + E+ + Sbjct: 1115 LKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPV-----FEEPVK 1169 Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889 + E V I LN + G+ A + RI P P VEW +G+V++ Sbjct: 1170 AEPDEGTVAPV------IEGLNDVV-VPLGREAKLDARITGSPKPE--VEWIKDGQVVED 1220 Query: 1890 GHR--YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927 R Y + + G +L I V ED+G+Y C A N G+ Sbjct: 1221 AGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 74.5 bits (175), Expect = 2e-12 Identities = 64/217 (29%), Positives = 97/217 (44%), Gaps = 20/217 (9%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG--Y 2433 PVF QPL++I I G+ A D ++ VG +V+W+R ++ IED R D G Sbjct: 17 PVFKQPLKDIIAIA-GEEAKLDV-IVSVG---AEVDWYRGDQAIEDKGRFMLVDDEGEGM 71 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQP 2493 S+ I V+ D G+Y C A N GE I + P +KIQ+ P Sbjct: 72 FSLLIDDVQPSDSGMYECVAFNNAGE-------VSSKAELIVNDGASPVPEEKIQEETAP 124 Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553 +E+P P+ T+ L E+ EG A E + + P++ EW + + ++ Sbjct: 125 -AVEAEKPSE--VAPLITEPLKS-LEVPEGATATLECKATGIPTPTV--EWRKDNIRVRE 178 Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G R +TT D + + I + D G Y C N G Sbjct: 179 GRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFG 215 Score = 74.5 bits (175), Expect = 2e-12 Identities = 56/198 (28%), Positives = 91/198 (45%), Gaps = 17/198 (8%) Query: 2263 ECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG--YVSLDIQHCVPEDAGEYSVKAI 2320 E +++ + +++Y +A++ RF + D G SL I P D+G Y A Sbjct: 33 EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAF 92 Query: 2321 NALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQ 2380 N G +S + I+++ P EKI+E E+A P E P V P+ T+ Sbjct: 93 NNAGEVSSKAEL-------IVNDGASPVPEEKIQE-ETA-PAVEAEKPSEVA---PLITE 140 Query: 2381 PLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISH 2440 PL++++ + EG TA +C+ G PT VEW ++ + + RI T D + + I Sbjct: 141 PLKSLE-VPEGATATLECKA--TGIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKD 197 Query: 2441 VRDEDEGVYMCRASNLLG 2458 D+G Y C N G Sbjct: 198 AIGTDQGEYKCMVKNDFG 215 Score = 73.3 bits (172), Expect = 4e-12 Identities = 74/266 (27%), Positives = 114/266 (42%), Gaps = 34/266 (12%) Query: 3546 DTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR 3605 DT P++++ P F D+I + A E +L + V+W+ + + R Sbjct: 8 DTTAPDSKA---PVFKQPLKDII----AIAGEEAKLDVIVSVGAEVDWYRGDQAIEDKGR 60 Query: 3606 VKTINDFG--FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663 ++D G L I V D+G+Y C A N GE VS K ++ G P+ Sbjct: 61 FMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGE--VSSKAELIVNDGASPVPE--- 115 Query: 3664 HFKSGTESIQKLEETLHKREEITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEP 3721 E IQ EET +E EKP+ P T +K +++VPEG +C+ Sbjct: 116 ------EKIQ--EETAP-----AVEAEKPSEVAPLITEPLK-SLEVPEGATATLECKA-- 159 Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781 G PT ++W + G R+ T D + + I D GEY C N +G T Sbjct: 160 TGIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYT 219 Query: 3782 TAKITCS--AKRDIVLESQLPQGMSG 3805 TAK+T + K V + + +G+ G Sbjct: 220 TAKLTVNVPVKPSFVKKMKPSEGIEG 245 Score = 72.5 bits (170), Expect = 8e-12 Identities = 56/211 (26%), Positives = 99/211 (46%), Gaps = 24/211 (11%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG++ C V +P+ +EW ++KPLP R ++ +L + ED +Y Sbjct: 1071 EGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALY 1128 Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVE-QAEEARLAKGRRPSVPD 2905 TC A+NS GS ++S L+ +K + + P E V+ + +E +A P + Sbjct: 1129 TCTASNSLGSVSSSAELQ-VDEKGVVPISPEPVSPVFEEPVKAEPDEGTVA----PVIEG 1183 Query: 2906 TEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL--T 2963 + ++P+ E +L + G +P ++EW +G+V+E RF Sbjct: 1184 LN----DVVVPLGREAKL----DARITGSPKP------EVEWIKDGQVVEDAGRFLYVEN 1229 Query: 2964 SDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 + G +L + DV D+G Y C A+N++GE Sbjct: 1230 EEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 72.1 bits (169), Expect = 1e-11 Identities = 118/488 (24%), Positives = 185/488 (37%), Gaps = 59/488 (12%) Query: 942 RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 +VEWLK+ V+ S RI + + LTIK D G Y C N G + A LT+ Sbjct: 796 KVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV 855 Query: 1002 VTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSA 1061 P + K++ E R + +VK + KP + GT KI E Sbjct: 856 RVPVK-------PSFVTKLKPTEAVEGGEARFDVKVKGSPKPE-VEWFSGTTKIAEKGRF 907 Query: 1062 HFEARVEPQ-----SDLTMTVEWYFNGKQITSANRIQTYHD-------FGYVALD----- 1104 FE E Q +DL +T A ++ + D F V D Sbjct: 908 RFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGP 967 Query: 1105 IASVRAEDSGVYTVVARNAAGEAQ-------LSASMTVETRSSIDTSSI--------HRG 1149 I E+ + +VV + + L S V+ RS DT ++ G Sbjct: 968 IKVQEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSG 1027 Query: 1150 LY--EKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDP 1207 Y E T + ++ + +++ K + P + EG++ + C E G P Sbjct: 1028 EYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAVMTC--EVTGKP 1085 Query: 1208 TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267 VEW + + + R Y+ L + A D YT A N LGS +SA + Sbjct: 1086 EPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAEL 1145 Query: 1268 RVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTN 1327 +V E+ + + + + K ++ TV AP L+++ G Sbjct: 1146 QVDEKGVVPISPEPVSPVFE--------EPVKAEPDEGTV--APVIE-GLNDVVVPLGRE 1194 Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY--EFDYVALDLLSVYPEDSGVYTC 1385 L+ R+ G VEW +G+ ++ RF E +L + V PED+G Y C Sbjct: 1195 AKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKC 1252 Query: 1386 QATNQLGE 1393 A N+ GE Sbjct: 1253 IAFNEKGE 1260 Score = 71.7 bits (168), Expect = 1e-11 Identities = 73/266 (27%), Positives = 110/266 (41%), Gaps = 26/266 (9%) Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740 K E+ T D K P F +KD I + G D V VG +DW+ + Sbjct: 5 KIEDTTAPDSKA--PVFKQPLKDIIAIA-GEEAKLDVIVS-VG---AEVDWYRGDQAIED 57 Query: 3741 GSRVHTLNDFG--FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798 R ++D G +L ID + D+G Y C A N G ++ A++ IV + Sbjct: 58 KGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGA 110 Query: 3799 LPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKED 3858 P + EKI+E E +A K + P +KS V E EC+ Sbjct: 111 SP--VPEEKIQE-ETAPAVEAEKPSEVA---PLITEPLKSLEVPEGATATLECKATGIPT 164 Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT--K 3916 P +EW ++ + G R +T D + + I D GEY C NDFG D+T K Sbjct: 165 PT--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAK 222 Query: 3917 ATISCKKLPDIILQNQVPRGMKRSEA 3942 T++ P + + + G++ EA Sbjct: 223 LTVNVPVKPSFVKKMKPSEGIEGGEA 248 Score = 71.3 bits (167), Expect = 2e-11 Identities = 81/339 (23%), Positives = 139/339 (41%), Gaps = 50/339 (14%) Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047 +V EG + +++ + P V+W NG+P++ + + I A +D+ Sbjct: 969 KVQEGEEISIKSVVKA--KPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDS 1026 Query: 2048 GTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQ 2107 G Y C+ATN+VG+A T SV+V+ K + K PK I E +P Q Sbjct: 1027 GEYTCEATNSVGKASRTYSVEVEKK------------------VPKGHAPKLIAEMRPMQ 1068 Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167 + EG+ A C V P +++W + + + R ++ Sbjct: 1069 -------------IIEGEDAVMTCEVT--GKPEPSVEWLKDDKPLPRDQRLTPMYNGEVA 1113 Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQG 2227 L + ED Y C A+N LG ++ L+V + ++ P E + + + Sbjct: 1114 TLKLQKAILEDEALYTCTASNSLGSVSSSAELQV-DEKGVV-----PISPEPVSPVFEE- 1166 Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287 + E +E ++P V E V G+ A + ++ P +E+ +G+ ++ Sbjct: 1167 -PVKAEPDEGTVAP---VIEGLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVED 1220 Query: 2288 AARFHI--TFDFGYVSLDIQHCVPEDAGEYSVKAINALG 2324 A RF + G SL I PEDAG+Y A N G Sbjct: 1221 AGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKG 1259 Score = 70.9 bits (166), Expect = 2e-11 Identities = 69/262 (26%), Positives = 115/262 (43%), Gaps = 32/262 (12%) Query: 3275 STPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334 + P ++ P F ++D+ + G+ EA+L + +V+W+ + + R+ Sbjct: 10 TAPDSKAPVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLV 64 Query: 3335 HDFGIVILDILY--CYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392 D G + +L +SG YECVA N G S+KA L ++ D P Sbjct: 65 DDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASP----- 112 Query: 3393 GLEKLQTLEDSMVRRKDTSVEEEKGK--APVFTVPLSNIENLREGENAHFEARLTPTDDP 3450 E+ + +VE EK AP+ T PL ++E + EG A E + T P Sbjct: 113 ------VPEEKIQEETAPAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKATGIPTP 165 Query: 3451 NLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA-- 3508 VEW + ++ G R +T D + + I D GEY C N++G TTA Sbjct: 166 T--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKL 223 Query: 3509 SMKVQGKRNIILESQLPKGMEG 3530 ++ V K + + + + +G+EG Sbjct: 224 TVNVPVKPSFVKKMKPSEGIEG 245 Score = 70.9 bits (166), Expect = 2e-11 Identities = 59/225 (26%), Positives = 94/225 (41%), Gaps = 25/225 (11%) Query: 3966 DVDKKQP----PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR 4021 +V+KK P P+ + +++ ++E E C++ G P VEW + KPL R Sbjct: 1047 EVEKKVPKGHAPKLIAEMRPM-QIIEGEDAVMTCEVT--GKPEPSVEWLKDDKPLPRDQR 1103 Query: 4022 FTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHM 4081 TP+Y+ + ED Y C A+N G + A ++ K G+V S P Sbjct: 1104 LTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEK-GVVPISPEPVSP 1162 Query: 4082 KSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPR 4141 E ++ E + PV L D V V G A+ R+TG PKP Sbjct: 1163 VFEEPVK-------------AEPDEGTVAPVIEGLND-VVVPLGREAKLDARITGSPKPE 1208 Query: 4142 VMWLLNGNTIVNGSRYKLTYD---GMYHFDIPKTRQYDTGKIEVI 4183 V W+ +G + + R+ + G++ I + D GK + I Sbjct: 1209 VEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCI 1253 Score = 70.1 bits (164), Expect = 4e-11 Identities = 71/232 (30%), Positives = 99/232 (42%), Gaps = 22/232 (9%) Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099 ++ P F PLK I G+ A + V ++ V+WY + I R D G Sbjct: 14 SKAPVFKQPLKDIIAIA-GEEAKLDVIVSVGAE----VDWYRGDQAIEDKGRFMLVDDEG 68 Query: 1100 --YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157 +L I V+ DSG+Y VA N AGE A + V +S EK + Sbjct: 69 EGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASPVPE-------EKIQ-- 119 Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217 EE+ P + E+ S+ P+ +PL + V EG LEC+ G PT VEW + Sbjct: 120 EETA---PAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKAT--GIPTPTVEWRKDN 173 Query: 1218 RSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269 V G R KT D + + I A D GEY N G +T+A + V Sbjct: 174 IRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV 225 Score = 69.7 bits (163), Expect = 5e-11 Identities = 69/255 (27%), Positives = 109/255 (42%), Gaps = 25/255 (9%) Query: 1278 DTQNEQAIEQIQLLEDAARR-TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQP 1336 D E E + A+R + +V + + AP+ + ++ +EG + + C + Sbjct: 1024 DDSGEYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAVMTCEV-- 1081 Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396 G VEW + KP+ R P Y + L L ED +YTC A+N LG + Sbjct: 1082 TGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSS 1141 Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENV 1456 S L+V +K ++ S P + + +E V +P T IE + Sbjct: 1142 SAELQV-DEKGVVPISPEP----------------VSPVFEEPVKAEPDEGTVAPVIEGL 1184 Query: 1457 IE-GQHVHFECKLEP-VTDS-NLKVEWFKNGQPVTIGHRFRPI--HDFGYVALDIIDLIA 1511 + + E KL+ +T S +VEW K+GQ V RF + + G +L I D+ Sbjct: 1185 NDVVVPLGREAKLDARITGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQP 1244 Query: 1512 EDSGIYTCRAVNLVG 1526 ED+G Y C A N G Sbjct: 1245 EDAGKYKCIAFNEKG 1259 Score = 69.7 bits (163), Expect = 5e-11 Identities = 58/198 (29%), Positives = 87/198 (43%), Gaps = 22/198 (11%) Query: 934 EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993 E G VEWLKD +P+ R+T +N L ++ + D YTC A N++G Sbjct: 1080 EVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSV 1139 Query: 994 TTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGP-LKGT 1052 ++SA L V +K ++ S P S EE VK + P ++G Sbjct: 1140 SSSAELQ-VDEKGVVPISPEP--------------VSPVFEEPVKAEPDEGTVAPVIEGL 1184 Query: 1053 NKIVE--GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRI--QTYHDFGYVALDIASV 1108 N +V G+ A +AR+ VEW +G+ + A R + G +L I V Sbjct: 1185 NDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDV 1242 Query: 1109 RAEDSGVYTVVARNAAGE 1126 + ED+G Y +A N GE Sbjct: 1243 QPEDAGKYKCIAFNEKGE 1260 Score = 68.9 bits (161), Expect = 9e-11 Identities = 61/225 (27%), Positives = 95/225 (42%), Gaps = 24/225 (10%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+ I ++ + ++ EG +A ++T +P+ VEW KD +P+ R+T ++N + Sbjct: 1058 PKLIAEMRPM-QIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVAT 1114 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889 L + ED YT A N LG S+A ++V + V PE Sbjct: 1115 LKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPIS---PEP------------ 1159 Query: 890 XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949 E T P + + + + G A +AR+ G VEW+KDG Sbjct: 1160 VSPVFEEPVKAEPDEGTVAPVIEG--LNDVVVPLGREAKLDARI--TGSPKPEVEWIKDG 1215 Query: 950 RPVEASSRITTFFNF--GYVALTIKSVTVHDAGHYTCRAYNAIGQ 992 + VE + R N G +L I V DAG Y C A+N G+ Sbjct: 1216 QVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 68.5 bits (160), Expect = 1e-10 Identities = 68/235 (28%), Positives = 101/235 (42%), Gaps = 23/235 (9%) Query: 903 PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962 P+S + P FK P+KD I+I A EA+L+ I V+W + + +E R Sbjct: 12 PDS-KAPVFKQPLKDIIAI-----AGEEAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVD 65 Query: 963 NFG--YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020 + G +L I V D+G Y C A+N G+ ++ A L I+ + P EKI Sbjct: 66 DEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASPVPEEKI 118 Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080 Q E A EV P PLK ++ EG +A E + T TVEW Sbjct: 119 QE-ETAPAVEAEKPSEV----APLITEPLKSL-EVPEGATATLECKA--TGIPTPTVEWR 170 Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 + ++ RI+T D + + I D G Y + +N G +A +TV Sbjct: 171 KDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV 225 Score = 68.1 bits (159), Expect = 2e-10 Identities = 74/239 (30%), Positives = 105/239 (43%), Gaps = 27/239 (11%) Query: 1303 EDITV--MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360 ED T +AP F + L +I + G L+ + VG + V+W+ + I+ RF Sbjct: 7 EDTTAPDSKAPVFKQPLKDIIAIAGEEAKLDV-IVSVGAE---VDWYRGDQAIEDKGRFM 62 Query: 1361 PAYEFDYVALDLL--SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL-ESQHPSG 1417 + LL V P DSG+Y C A N GE V +K +LI+ + P Sbjct: 63 LVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGE--------VSSKAELIVNDGASPVP 114 Query: 1418 LEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRP-KSIENVIEGQHVHFECKLEPVTDSNL 1476 EKIQ E+T+ + + E + P +T P KS+E V EG ECK + Sbjct: 115 EEKIQ--EETAPAVEAEKPSE---VAP-LITEPLKSLE-VPEGATATLECKATGIPTPT- 166 Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 VEW K+ V G R + D + + I D I D G Y C N G D + +LT Sbjct: 167 -VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLT 224 Score = 68.1 bits (159), Expect = 2e-10 Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 18/219 (8%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+ I ++ + +EG + G P +EWLK+ + + R T ++ +L Sbjct: 1058 PKLIAEMRPMQIIEGEDAVMTCEV--TGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATL 1115 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756 + ++D YTC A ++ G + A L V + + + PE + + + Sbjct: 1116 KLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPIS---PEPVSPV--------F 1164 Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816 + E I L D+ + GR A +A++T P VEW KDG+ + + Sbjct: 1165 EEPVKAEPDEGTVAPVIEGLNDV-VVPLGREAKLDARIT--GSPKPEVEWIKDGQVVEDA 1221 Query: 817 SRITSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGE 853 R + N G SL I ++ EDAG Y A N+ GE Sbjct: 1222 GRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 67.7 bits (158), Expect = 2e-10 Identities = 59/226 (26%), Positives = 95/226 (42%), Gaps = 18/226 (7%) Query: 2130 ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKAT 2187 E +++ I +DW+ Q I R+ D G +L + DSG Y C A Sbjct: 33 EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAF 92 Query: 2188 NKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTE 2247 N GE + L I+ D P EKI++ A +E E+P P +TE Sbjct: 93 NNAGEVSSKAEL-------IVNDGASPVPEEKIQEETAPA----VEAEKPSEVAP-LITE 140 Query: 2248 LRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHC 2307 + V EG TA EC+ + P +E+ + ++ R T D + + I+ Sbjct: 141 PLKSLEVPEGATATLECKATGIPTPT--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDA 198 Query: 2308 VPEDAGEYSVKAINALG--HCTSAISMTVTAKGSIISESQRPEGLE 2351 + D GEY N G + T+ +++ V K S + + + EG+E Sbjct: 199 IGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVKPSFVKKMKPSEGIE 244 Score = 67.3 bits (157), Expect = 3e-10 Identities = 66/236 (27%), Positives = 97/236 (41%), Gaps = 18/236 (7%) Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886 S Y + +V AP+ I ++ P ++ EG+ A C + P+P+ VEW + K Sbjct: 1041 SRTYSVEVEKKVPKGHAPKLIAEMR-PMQIIEGEDAVMTCEVTGKPEPS--VEWLKDDKP 1097 Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946 L R + A L + ED YTC A N+LG SS L V K + Sbjct: 1098 LPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISP 1157 Query: 1947 QHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND 2006 + S + E+ +A D+ V P + + + V G L+A +T Sbjct: 1158 EPVSPV-----FEEP---VKAEPDEGTVA--PVI-EGLNDVVVPLGREAKLDARIT--GS 1204 Query: 2007 PTMRVEWYCNGRPVQQGHRF--KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060 P VEW +G+ V+ RF + G +L I ED G Y C A N GE Sbjct: 1205 PKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 66.5 bits (155), Expect = 5e-10 Identities = 69/248 (27%), Positives = 99/248 (39%), Gaps = 25/248 (10%) Query: 3404 MVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL 3463 MV +K KAPVF PL +I + GE EA+L +V+WY +++ Sbjct: 1 MVPQKIEDTTAPDSKAPVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAI 55 Query: 3464 KAGSRFRTFCDFG--FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521 + RF D G L I P DSG Y C A+NN GE + A + V + + E Sbjct: 56 EDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASPVPE 115 Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL 3581 ++ E T + A E S P T L + E ++A EC+ Sbjct: 116 EKI---QEETAPAVEA-------------EKPSEVAPLITEPLKSLEVPEGATATLECKA 159 Query: 3582 IPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA 3641 + + VEW + + G R+KT D + + I D G Y C N G Sbjct: 160 TGI--PTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLD 217 Query: 3642 TVSCKLQV 3649 + KL V Sbjct: 218 YTTAKLTV 225 Score = 66.5 bits (155), Expect = 5e-10 Identities = 67/261 (25%), Positives = 109/261 (41%), Gaps = 23/261 (8%) Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196 K+E + P F +++I + G+ A + +V V +++WY Q + Sbjct: 5 KIEDTTAPDSKAPVFKQPLKDIIAIA-GEEAKLD-VIVSVG---AEVDWYRGDQAIEDKG 59 Query: 3197 RIKTVSDFG--FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254 R V D G L I Q DSG Y C A+N GE ++A + + + P Sbjct: 60 RFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASP 112 Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314 KI+E E+ + + PS E IT+ ++ EG +A E + + P Sbjct: 113 VPEEKIQE-ETAPAVEAEKPS----EVAPLITEPLKSLEVPEGATATLECKATGIPTPT- 166 Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL-- 3372 VEW + ++ G R +T D + + I + GEY+C+ N G D T A L Sbjct: 167 -VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV 225 Query: 3373 KCTSKENLILDSQLPRGMEGG 3393 K + + + G+EGG Sbjct: 226 NVPVKPSFVKKMKPSEGIEGG 246 Score = 65.3 bits (152), Expect = 1e-09 Identities = 73/289 (25%), Positives = 118/289 (40%), Gaps = 36/289 (12%) Query: 3039 QPDDDTGRPPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRI 3097 Q +DT P VFK + DI IA EA L ++W+ + IE R Sbjct: 4 QKIEDTTAPDSKAPVFKQPLKDIIA--IAGEEAKLDVIVSVGAEVDWYRGDQAIEDKGRF 61 Query: 3098 RTV--YAFGMVVLEILGTKTTDSGTYSCRATNKWGQ----AEISV----------KLE-- 3139 V GM L I + +DSG Y C A N G+ AE+ V K++ Sbjct: 62 MLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASPVPEEKIQEE 121 Query: 3140 ---CVDKSKGQK--PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194 V+ K + P T ++++E + +G +A EC + P +EW + +R Sbjct: 122 TAPAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKATGIPTPT--VEWRKDNIRVRE 178 Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254 RIKT D + + I D GEY C N +G D+T A + ++P Sbjct: 179 GRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVN-------VPVKP 231 Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFE 3303 + K++ E ++G + + P + + +TK+ + + H E Sbjct: 232 SFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVE 280 Score = 65.3 bits (152), Expect = 1e-09 Identities = 57/219 (26%), Positives = 95/219 (43%), Gaps = 18/219 (8%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P+ + + ++ +IEG+ C++ + + VEW K+ +P+ R P+++ Sbjct: 1058 PKLIAEMRPMQ-IIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVAT 1114 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563 L + I ED +YTC A N +G+ S L + S + + V E+ K Sbjct: 1115 LKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVS-----PVFEEPVK 1169 Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623 DE T AP+ L +V + G+ A + R+ +VEW + + ++ Sbjct: 1170 AE----PDEGTV-APV-IEGLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDA 1221 Query: 1624 SRF--TETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 RF E G +L I PED+G Y C A N GE Sbjct: 1222 GRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 64.5 bits (150), Expect = 2e-09 Identities = 67/243 (27%), Positives = 101/243 (41%), Gaps = 24/243 (9%) Query: 625 IPPGEEDRVYPP---PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEA 681 +P ED P P F PLK + A+ G E +++ + +++W + Q+IE Sbjct: 2 VPQKIEDTTAPDSKAPVFKQPLKDIIAIAGE----EAKLDVIVSVGAEVDWYRGDQAIED 57 Query: 682 SSRFTSIFRFGYISLDMLSLNIQ--DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQ 739 RF + G +L ++Q DSG Y C A + G +KA L V A S Sbjct: 58 KGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGA-----SP 112 Query: 740 HPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSD 799 PE + IQ+ + E+ + P PL+ L E+ EG A E + T + Sbjct: 113 VPE--EKIQE-----ETAPAVEAEKPSEVAPLITEPLKSL-EVPEGATATLECKATGIPT 164 Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 PT VEW KD + RI + + + + I D G Y N G +TA Sbjct: 165 PT--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAK 222 Query: 860 IRV 862 + V Sbjct: 223 LTV 225 Score = 64.5 bits (150), Expect = 2e-09 Identities = 61/229 (26%), Positives = 96/229 (41%), Gaps = 22/229 (9%) Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG--F 2565 P+F Q L + G+ A + +V VG +WY ++ RF D G Sbjct: 17 PVFKQPLKDIIAI-AGEEAKLDV-IVSVG---AEVDWYRGDQAIEDKGRFMLVDDEGEGM 71 Query: 2566 VTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAA 2625 +L I+ V +D+G+Y C A N AG I++ P E+IQ + A Sbjct: 72 FSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASPVPEEKIQEETA- 123 Query: 2626 MNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL 2685 P + + + AP+ T LKS + + EG LE + P +EW K+ + + Sbjct: 124 ----PAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKATGIPTPT--VEWRKDNIRV 176 Query: 2686 TTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 G R+K+T D + + I D G Y C N G +TA + + Sbjct: 177 REGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV 225 Score = 64.1 bits (149), Expect = 3e-09 Identities = 59/246 (23%), Positives = 101/246 (41%), Gaps = 21/246 (8%) Query: 3669 TESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMR 3728 T S+ K T E + K + P+ E++ + + EG C V G P Sbjct: 1034 TNSVGKASRTYSVEVEKKVP--KGHAPKLIAEMRP-MQIIEGEDAVMTCEV--TGKPEPS 1088 Query: 3729 IDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788 ++W + +P R+ + + L + D YTC A+N GS +++A++ Sbjct: 1089 VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVD 1148 Query: 3789 AKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVR 3848 K +P +S E + + + K EP T I + V + Sbjct: 1149 EK------GVVP--ISPEPVSPV----FEEPVKAEPDEGTVAPVIEGLNDVVVPLGREAK 1196 Query: 3849 FECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV--YDMGFVSLDILYVYAEDSGEYICRA 3906 + R+ PK +EW ++G+++ R+ V + G SL I V ED+G+Y C A Sbjct: 1197 LDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIA 1254 Query: 3907 VNDFGE 3912 N+ GE Sbjct: 1255 FNEKGE 1260 Score = 62.9 bits (146), Expect = 6e-09 Identities = 99/400 (24%), Positives = 153/400 (38%), Gaps = 47/400 (11%) Query: 760 ESIEEQT---SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816 + IE+ T S+ P F +PL+D+ + A EA+L + V+WY+ + I Sbjct: 4 QKIEDTTAPDSKAPVFKQPLKDIIAI-----AGEEAKLDVIVSVGAEVDWYRGDQAIEDK 58 Query: 817 SRITSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874 R + + G SL I ++ D+G Y A N GE S A + V ++ + Sbjct: 59 GRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASP-----V 113 Query: 875 PEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLE 934 PE++ E+T S P P+K + + EG A E + Sbjct: 114 PEEKIQ-EETAPAVEAEK-----------PSEVAPLITEPLKS-LEVPEGATATLECKAT 160 Query: 935 PIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQAT 994 I T VEW KD V RI T + + + IK D G Y C N G Sbjct: 161 GIPTPT--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDY 218 Query: 995 TSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNK 1054 T+A LT+ P ++K++ E R + ++K + KP + +G K Sbjct: 219 TTAKLTVNV-------PVKPSFVKKMKPSEGIEGGEARFDVQIKGSPKPD-VEWFRGMTK 270 Query: 1055 IVEGQSAHFEARVEPQ-----SDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVR 1109 I + + H E E Q DL F A +I D A + Sbjct: 271 ITDKERFHVEETGEDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKERQFAPI- 329 Query: 1110 AEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRG 1149 ED + V+ R G+ +LS T+ + D + H G Sbjct: 330 FEDEQMGPVILRK--GD-ELSIKETIRAKPKPDVNWYHNG 366 Score = 62.5 bits (145), Expect = 8e-09 Identities = 48/189 (25%), Positives = 81/189 (42%), Gaps = 14/189 (7%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA----F 3103 P F K I G+ A ++ + G +EWF I R + Sbjct: 231 PSFVKKMKPSEGIEGGE-ARFDVQI--KGSPKPDVEWFRGMTKITDKERFHVEETGEDQY 287 Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 +V+++++ T D+G + C A+N+ G+ I+ + + K + P F L+ Sbjct: 288 SLVIIDLV---TEDAGVFKCVASNEAGK--ITARADLTVKERQFAPIFEDEQMGPVILRK 342 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G + T+ PD + WYHNG+P+R + + S L I + D+GEY Sbjct: 343 GDELSIKETIRAKPKPD--VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYR 400 Query: 3224 CRAYNKYGE 3232 C A+NK G+ Sbjct: 401 CEAHNKLGK 409 Score = 62.1 bits (144), Expect = 1e-08 Identities = 46/205 (22%), Positives = 87/205 (42%), Gaps = 15/205 (7%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712 +++EG+ + +V + +P+ +EW K+ L RL ++ + TL + +D Sbjct: 1068 QIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDE 1125 Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXX 2772 +YTC A+N LG S+A ++++++ + + P+ + + Sbjct: 1126 ALYTCTASNSLGSVSSSAELQVDEKGVV---PISPEPVSPV------FEEPVKAEPDEGT 1176 Query: 2773 XXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTR--YKSTHDFSY 2830 I LN++V G + + S P ++EW + + + R Y + Sbjct: 1177 VAPVIEGLNDVVVPLGREAKLDARITGSPKP--EVEWIKDGQVVEDAGRFLYVENEEPGI 1234 Query: 2831 VSLDITHTYEEDSGIYTCKATNSKG 2855 SL I ED+G Y C A N KG Sbjct: 1235 FSLVIDDVQPEDAGKYKCIAFNEKG 1259 Score = 61.7 bits (143), Expect = 1e-08 Identities = 103/390 (26%), Positives = 161/390 (41%), Gaps = 64/390 (16%) Query: 3392 GGLEKLQTLEDSMVR-RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDP 3450 G ++ + T E V R D +V+E APVF ++EGE ++ + P Sbjct: 930 GTIKCIATNEAGKVTSRADLNVKERLF-APVFEDEEQGPIKVQEGEEISIKSVVKAK--P 986 Query: 3451 NLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASM 3510 V+W NGK LK S+ + I +DSGEY C A N+ G+A T S+ Sbjct: 987 KADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSV 1046 Query: 3511 KVQGKRNIILESQLPKG-MEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLIL 3569 +V E ++PKG I ++ ++ G +T E +G P PS L Sbjct: 1047 EV--------EKKVPKGHAPKLIAEMRPMQIIEGEDAVMTCEV-TGKP-----EPSVEWL 1092 Query: 3570 SENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGL 3629 ++ + RL P+ +NG+ V T+ ILE +Y Sbjct: 1093 KDDKPLPRDQRLTPM----------YNGE-------VATLK-LQKAILEDEALY------ 1128 Query: 3630 YTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIED 3689 TC A+N G + S +LQV + + + P E + + E K E D Sbjct: 1129 -TCTASNSLGSVSSSAELQVDEKGVVPISP----------EPVSPVFEEPVKAE----PD 1173 Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLN 3748 E P +E +++ VP G D R+ G P ++W +G+ R ++ N Sbjct: 1174 EGTVAP--VIEGLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVEN 1229 Query: 3749 DF-GFIALDIDYIYARDAGEYTCRATNKWG 3777 + G +L ID + DAG+Y C A N+ G Sbjct: 1230 EEPGIFSLVIDDVQPEDAGKYKCIAFNEKG 1259 Score = 60.5 bits (140), Expect = 3e-08 Identities = 63/247 (25%), Positives = 103/247 (41%), Gaps = 23/247 (9%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG--F 1234 PVF QPL + ++ G+ E +L+ + V+W+ +++ RF D G Sbjct: 17 PVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGM 71 Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDA 1294 +L I +D+G Y A N+ G + A + IV D + E+IQ E+ Sbjct: 72 FSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASPVPEEKIQ--EET 122 Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354 A + + AP + L ++E EG LEC+ G T VEW + ++ Sbjct: 123 APAVEAEKPSEV---APLITEPLKSLEVPEGATATLECKA--TGIPTPTVEWRKDNIRVR 177 Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV-IAKKDLILESQ 1413 G R + + D + + + D G Y C N G T+ L V + K ++ Sbjct: 178 EGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVKPSFVKKM 237 Query: 1414 HPS-GLE 1419 PS G+E Sbjct: 238 KPSEGIE 244 Score = 60.5 bits (140), Expect = 3e-08 Identities = 50/217 (23%), Positives = 94/217 (43%), Gaps = 16/217 (7%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P+ ++ ++ EG + +T +P+ VEW + +P+ + R Y+ L Sbjct: 1058 PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVATL 1115 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097 + A ED Y C A+N++G +++ ++VD K + + + + + +E P Sbjct: 1116 KLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKG---VVPISPEPVSPV-----FEEP 1167 Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157 E ++ PV + L + + G A + R+ P ++W +GQ + R Sbjct: 1168 VKAEPDEGTVAPV-IEGLNDVV-VPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGR 1223 Query: 2158 --YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE 2192 Y + G +L I ED+G Y C A N+ GE Sbjct: 1224 FLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 59.7 bits (138), Expect = 6e-08 Identities = 58/238 (24%), Positives = 92/238 (38%), Gaps = 38/238 (15%) Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 R ++ ++ E+ P F E + I V EG + V+ P + W NG+P Sbjct: 946 RADLNVK-ERLFAPVFEDEEQGPIKVQEGEEISIKSVVK--AKPKADVKWMKNGKPLKDS 1002 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801 S+V + + I D+GEYTC ATN G A S + +E ++P+ Sbjct: 1003 SKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKA--------SRTYSVEVEKKVPK 1054 Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861 G + PK I +++ + E E C V K +P Sbjct: 1055 GHA-------------------------PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPS- 1088 Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 +EW ++ K LP R +Y+ +L + ED Y C A N G + A + Sbjct: 1089 -VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAEL 1145 Score = 59.3 bits (137), Expect = 8e-08 Identities = 73/270 (27%), Positives = 114/270 (42%), Gaps = 44/270 (16%) Query: 1934 LNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGH 1993 L + K++I D + K + D + K V V KP F K +K +E EG Sbjct: 191 LRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVN----VPVKPSFVKKMKPSEGIEGG 246 Query: 1994 PVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF--KTTYDFGYVALDILYAYAEDTGTYM 2051 + + P VEW+ + RF + T + Y +L I+ ED G + Sbjct: 247 EARFDVQIK--GSPKPDVEWFRGMTKITDKERFHVEETGEDQY-SLVIIDLVTEDAGVFK 303 Query: 2052 CKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVF 2111 C A+N G K+ A++ L T+ E++ I E+EQ G PV Sbjct: 304 CVASNEAG--------KITARADL---TVKERQFAPI-----------FEDEQMG--PVI 339 Query: 2112 LTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDI 2171 L L ++KE RA P ++W+HNG+ +R+ +L I Sbjct: 340 LRKGDEL-SIKETIRAK----------PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAI 388 Query: 2172 LYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + ED+G Y C+A NKLG+A+ T ++V Sbjct: 389 ISAKLEDAGEYRCEAHNKLGKALRTYDVRV 418 Score = 58.4 bits (135), Expect = 1e-07 Identities = 29/97 (29%), Positives = 55/97 (56%), Gaps = 2/97 (2%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP+F + K+ EG+ + +++ V+ + P ++W KNG L +++ Sbjct: 957 APVFEDEEQGPIKVQEGEEISIKSVVKAK--PKADVKWMKNGKPLKDSSKVDVRSRDDTH 1014 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 ++I + + DDSG YTC+ATN +G+A T S+++E + Sbjct: 1015 NVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKK 1051 Score = 57.6 bits (133), Expect = 2e-07 Identities = 63/279 (22%), Positives = 106/279 (37%), Gaps = 22/279 (7%) Query: 2629 VPEMFVDTGV--QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLT 2686 VP+ DT +AP+F LK + G+ EA+++ +++W++ + Sbjct: 2 VPQKIEDTTAPDSKAPVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAIE 56 Query: 2687 TGARLKSTFDFG--LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744 R D G + +L I+ ++ DSG+Y C A N GE S A + + D G S Sbjct: 57 DKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVND-----GAS 111 Query: 2745 LHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPT 2804 P+ + + L ++ EG EC + + PT Sbjct: 112 PVPEE-----KIQEETAPAVEAEKPSEVAPLITEPLKSLEVPEGATATLEC--KATGIPT 164 Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864 +EW +N + G R K+T D + + I D G Y C N G T+ L Sbjct: 165 PTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLT 224 Query: 2865 CTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903 F + + G+E E + ++ +P V Sbjct: 225 VNVPVKPSF-VKKMKPSEGIEGGEARFDVQIKGSPKPDV 262 Score = 56.0 bits (129), Expect = 7e-07 Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 3/115 (2%) Query: 1826 DSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884 ++ + R D+ V Q AP F + GP L +G + I P P+ V WY NG Sbjct: 309 EAGKITARADLTVKERQFAPIFEDEQMGPVILRKGDELSIKETIRAKPKPD--VNWYHNG 366 Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 K L+S + +L I++ ED+GEY C+A N LG+A+ + + V+ + Sbjct: 367 KPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQ 421 Score = 54.4 bits (125), Expect = 2e-06 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 3/126 (2%) Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPD 1873 +S K ++ + R D+ V AP F + GP K+ EG+ + ++ P Sbjct: 928 DSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPK 987 Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933 + V+W NGK L+ + + + I T +DSGEYTC+A N++G+A + Sbjct: 988 AD--VKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYS 1045 Query: 1934 LNVQSK 1939 + V+ K Sbjct: 1046 VEVEKK 1051 Score = 54.4 bits (125), Expect = 2e-06 Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 22/227 (9%) Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475 KG AP + ++ + EGE+A +T +P+ VEW + K L R + Sbjct: 1054 KGHAPKLIAEMRPMQII-EGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNG 1110 Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKI 3535 L++ ED Y C A N+ G ++A ++V K + + P+ + ++ Sbjct: 1111 EVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPIS---PEPVSPVFEEP 1167 Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595 E GTV P E N D+++ A + R+ VEW Sbjct: 1168 VKAEPDEGTV---APVIEGLN---------DVVVPLGREAKLDARI--TGSPKPEVEWIK 1213 Query: 3596 NGKPLLTGSRVKTI--NDFGFVILEIGGVYQRDAGLYTCKATNRHGE 3640 +G+ + R + + G L I V DAG Y C A N GE Sbjct: 1214 DGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 52.4 bits (120), Expect = 9e-06 Identities = 50/172 (29%), Positives = 70/172 (40%), Gaps = 18/172 (10%) Query: 3994 ECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG--YVAMNFGWVYPEDSGEYLCRAT 4051 E +L + +V+W+ + + K RF + D G ++ V P DSG Y C A Sbjct: 33 EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAF 92 Query: 4052 NLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPP 4111 N G +KA + IV D P EKI+E T V E + P Sbjct: 93 NNAGEVSSKAEL-------IVNDGASPVPE---EKIQEE------TAPAVEAEKPSEVAP 136 Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163 + ++ V EG A C+ TG P P V W + + G R K T DG Sbjct: 137 LITEPLKSLEVPEGATATLECKATGIPTPTVEWRKDNIRVREGRRIKTTQDG 188 Score = 52.0 bits (119), Expect = 1e-05 Identities = 30/105 (28%), Positives = 57/105 (54%), Gaps = 6/105 (5%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEA--RLEPIGDSTLRVEWLKDGRPVEASSRIT 959 V E P F+ + I ++EG ++ + +P D V+W+K+G+P++ SS++ Sbjct: 951 VKERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPKAD----VKWMKNGKPLKDSSKVD 1006 Query: 960 TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 +TIK+ V D+G YTC A N++G+A+ + ++ + K Sbjct: 1007 VRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKK 1051 Score = 51.6 bits (118), Expect = 2e-05 Identities = 85/333 (25%), Positives = 133/333 (39%), Gaps = 69/333 (20%) Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS--DFGFVTLDLVDVYERDSG 2982 EG+ + ++ V+ K D+K W NGK L+ S+ + S D VT+ V DSG Sbjct: 972 EGEEISIKSVVKAKPKADVK--WMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKV--DDSG 1027 Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDD 3042 YTC+A N G+A S Y + + + PK + +Q +E E + Sbjct: 1028 EYTCEATNSVGKA---SRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEG----EDAVMTCE 1080 Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102 TG+P KD + Q L P YNG+ A+ +++ Sbjct: 1081 VTGKPEPSVEWLKDDKPLPRDQ------RLTP----------MYNGEV--ATLKLQ---- 1118 Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS------KGQKPRFTTHIQ 3156 +LE D Y+C A+N G S +L+ +K + P F ++ Sbjct: 1119 --KAILE-------DEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPVFEEPVK 1169 Query: 3157 N----------IEGLKD-----GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201 IEGL D G+ A + + P ++EW +GQ + + R V Sbjct: 1170 AEPDEGTVAPVIEGLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYV 1227 Query: 3202 --SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 + G L I Q D+G+Y C A+N+ GE Sbjct: 1228 ENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 51.2 bits (117), Expect = 2e-05 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 3/101 (2%) Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT-SIFR 690 RV P F+ LK A+EGG+ F+ +++ G P ++EW I RF Sbjct: 856 RVPVKPSFVTKLKPTEAVEGGEARFDVKVK--GSPKPEVEWFSGTTKIAEKGRFRFEEVG 913 Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 SL + L + DSG C A + G ++A L+V R Sbjct: 914 EEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKER 954 Score = 51.2 bits (117), Expect = 2e-05 Identities = 53/212 (25%), Positives = 88/212 (41%), Gaps = 21/212 (9%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 Q++EG+ + +V K +P +EW + K L + R + TL L D Sbjct: 1068 QIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDE 1125 Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD 3041 +YTC A N G +S+ + K + P E + + E+ ++ EP Sbjct: 1126 ALYTCTASNSLGSVSSSAELQVDEKGVV------PISPEPVSPV--FEEPVKAEP----- 1172 Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV- 3100 D G D+V + G+ A +A + TG +EW +G+ +E + R V Sbjct: 1173 -DEGTVAPVIEGLNDVV-VPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVE 1228 Query: 3101 -YAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131 G+ L I + D+G Y C A N+ G+ Sbjct: 1229 NEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 50.4 bits (115), Expect = 3e-05 Identities = 61/224 (27%), Positives = 92/224 (41%), Gaps = 42/224 (18%) Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499 V +KP FVT+ K E +EG F+ K++ +VEWF + RFR + Sbjct: 857 VPVKPSFVTKLKPTE-AVEGGEARFDVKVKG--SPKPEVEWFSGTTKIAEKGRFR-FEEV 912 Query: 1500 G--YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557 G +L + DL DSG C + T+E ++T R+ ++ V Sbjct: 913 GEEQFSLVLTDLQLTDSGTIKC-----IATNEAG-KVTSRADLNVKERLF-------APV 959 Query: 1558 LEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNN 1617 ED Q PI + + IK +A P +D V+W N Sbjct: 960 FEDEE-------------QGPIKVQEGEEISIKSVVKAK------PKAD----VKWMKNG 996 Query: 1618 KPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 KPLK S+ + + I + +DSG YTC A N++G+A Sbjct: 997 KPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKA 1040 Score = 50.0 bits (114), Expect = 5e-05 Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 5/94 (5%) Query: 61 ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120 + A +P E +P I E + K+ +G A E K G PTP V W + + E + Sbjct: 126 VEAEKPSEVAPLITEPL-KSLEVPEGATATLECKATGIPTPTVEWRKDNIRVREGRRIK- 183 Query: 121 RYNEQTGD-VSLLIKQIGPGDEGEYTCTARNQYG 153 Q GD + ++IK D+GEY C +N +G Sbjct: 184 --TTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFG 215 Score = 49.6 bits (113), Expect = 6e-05 Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 6/101 (5%) Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498 +V +KP FV + K E IEG F+ +++ + VEWF+ +T RF + + Sbjct: 226 NVPVKPSFVKKMKPSEG-IEGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFH-VEE 281 Query: 1499 FG--YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537 G +L IIDL+ ED+G++ C A N G LT + Sbjct: 282 TGEDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVK 322 Score = 49.2 bits (112), Expect = 8e-05 Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 4/119 (3%) Query: 3416 KGKAPVFTVP--LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 K KAP P L I+ L GE+ + LT T + KVEW N +K R ++ Sbjct: 757 KFKAPAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKA 816 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA--SMKVQGKRNIILESQLPKGMEG 3530 D L I + ED G Y C N+YG + A +++V K + + + + + +EG Sbjct: 817 DNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAVEG 875 Score = 48.8 bits (111), Expect = 1e-04 Identities = 26/88 (29%), Positives = 47/88 (53%), Gaps = 5/88 (5%) Query: 69 PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128 P P F + K + +GG A+F+ +++G+P P V W R + + ++ + E+TG+ Sbjct: 228 PVKPSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHV---EETGE 284 Query: 129 --VSLLIKQIGPGDEGEYTCTARNQYGE 154 SL+I + D G + C A N+ G+ Sbjct: 285 DQYSLVIIDLVTEDAGVFKCVASNEAGK 312 Score = 48.8 bits (111), Expect = 1e-04 Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 6/96 (6%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 PQ +PI+ EV E V L T T P +VEW N V++ +R K+ D L Sbjct: 766 PQILEPIQPLEVGEDQIVKLTLTFTSEQAP--KVEWLKNNIRVKESYRIKSKADNDTATL 823 Query: 2038 DILYAYAEDTGTYMCKATNAVG----EAVTTSSVKV 2069 I + AED G Y C N G EA+ T V V Sbjct: 824 TIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPV 859 Score = 48.4 bits (110), Expect = 1e-04 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK-HEIITTHNHTTLR 324 P +K + S+ EG +A+F VQ+ G+P+P V WF+ ++ + + H T + +L Sbjct: 231 PSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQYSLV 290 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356 + + D+G + +A N G I L V+ Sbjct: 291 IIDLVTEDAGVFKCVASNEAGKITARADLTVK 322 Score = 48.4 bits (110), Expect = 1e-04 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 3/97 (3%) Query: 1710 APVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 APVF + I+V E + ++ + PK V+W++NG P++ S+++ Sbjct: 957 APVFEDEEQGPIKVQEGEEISIKS--VVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTH 1014 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + +K +DSG YTC A N +G+A + ++ V+ K Sbjct: 1015 NVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKK 1051 Score = 48.0 bits (109), Expect = 2e-04 Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 8/153 (5%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG--KVLQSGH-RYR 1894 V V P F+T+L PT+ EG A ++ +++ P P VEW F+G K+ + G R+ Sbjct: 855 VRVPVKPSFVTKLK-PTEAVEGGEARFDVKVKGSPKP--EVEW-FSGTTKIAEKGRFRFE 910 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954 + F +L + + DSG C A N G+ S LNV+ + E K Sbjct: 911 EVGEEQF-SLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIK 969 Query: 1955 IQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNA 1987 +Q E+ S V+ + GKP+K++ Sbjct: 970 VQEGEEISIKSVVKAKPKADVKWMKNGKPLKDS 1002 Score = 47.6 bits (108), Expect = 2e-04 Identities = 59/257 (22%), Positives = 100/257 (38%), Gaps = 35/257 (13%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVS 2832 VF L +I+ G+ + V + ++W+ ++ + R+ D S Sbjct: 18 VFKQPLKDIIAIAGEEAKLDVIVSVGAE----VDWYRGDQAIEDKGRFMLVDDEGEGMFS 73 Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE 2892 L I DSG+Y C A N+ G ++ L I D P E Sbjct: 74 LLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASP-----------VPE 115 Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKNDPDLKIEWY 2948 ++ + P+V E KP + P+ E ++ EG LE + P +EW Sbjct: 116 EKIQEETAPAV---EAEKPSEVAPLITEPLKSLEVPEGATATLE--CKATGIPTPTVEWR 170 Query: 2949 FNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS--TVYCTSK 3006 + + +G R K T D + + + D D G Y C N G +T++ TV K Sbjct: 171 KDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVK 230 Query: 3007 DNLIERTQHPKGTEGLE 3023 + +++ + +G EG E Sbjct: 231 PSFVKKMKPSEGIEGGE 247 Score = 46.8 bits (106), Expect = 4e-04 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 2/99 (2%) Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698 Q APIF L +G + ++ + + P+ + W+ NG L + L Sbjct: 325 QFAPIFEDEQMGPVILRKGDELSIKETIRAKPKPD--VNWYHNGKPLRSAPTLDIRSRGD 382 Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 +L+I S + +D+G Y C+A N LG+A+ T +++E++ Sbjct: 383 THSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQ 421 Score = 46.0 bits (104), Expect = 8e-04 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066 P V WY NG+P++ +L I+ A ED G Y C+A N +G+A+ T Sbjct: 356 PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYD 415 Query: 2067 VKVD--AKSGLYLDTLDEQRLKKIQELE 2092 V+V+ A G L E + +++ E E Sbjct: 416 VRVEEQAPKGTAPTILSEMKPQQVVEGE 443 Score = 46.0 bits (104), Expect = 8e-04 Identities = 23/63 (36%), Positives = 34/63 (53%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P V WY +G+P+ ++ + SL I+ + EDAG Y A NKLG+A+ T Sbjct: 356 PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYD 415 Query: 860 IRV 862 +RV Sbjct: 416 VRV 418 Score = 46.0 bits (104), Expect = 8e-04 Identities = 21/60 (35%), Positives = 30/60 (50%) Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 K+EW KN + + R+KS D TL+I R +D G+Y C N G S A + + Sbjct: 796 KVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV 855 Score = 46.0 bits (104), Expect = 8e-04 Identities = 38/158 (24%), Positives = 71/158 (44%), Gaps = 11/158 (6%) Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900 V+E E + + V+ K PK ++W +NGK L + ++ I +DSG Sbjct: 970 VQEGEEISIKSVVKAK--PKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSG 1027 Query: 3901 EYICRAVNDFGEDFTKATISCKK------LPDIILQNQVPRGMKRSEALTQMEATIKKYT 3954 EY C A N G+ ++ +K P +I + + + ++ +A+ E T K Sbjct: 1028 EYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEP 1087 Query: 3955 SEVYLTEDDLYDVDKKQPPRF---VTQIQSQTSLVEME 3989 S +L +D D++ P + V ++ Q +++E E Sbjct: 1088 SVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDE 1125 Score = 45.2 bits (102), Expect = 0.001 Identities = 26/82 (31%), Positives = 38/82 (46%) Query: 2377 VFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSM 2436 V Q L+ I ++ G+ L + KVEW +N +++S RI D ++ Sbjct: 764 VAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKADNDTATL 823 Query: 2437 TISHVRDEDEGVYMCRASNLLG 2458 TI R ED+GVY C N G Sbjct: 824 TIKQSRAEDQGVYQCVIRNDYG 845 Score = 44.8 bits (101), Expect = 0.002 Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 6/87 (6%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFG 2432 +P F + ++ + I+ G+ A FD ++ G P VEWFR I D R + +T + Sbjct: 230 KPSFVKKMKPSEGIEGGE-ARFDVQI--KGSPKPDVEWFRGMTKITDKERFHVEETGEDQ 286 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459 Y S+ I + ED GV+ C ASN G+ Sbjct: 287 Y-SLVIIDLVTEDAGVFKCVASNEAGK 312 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/101 (27%), Positives = 57/101 (56%), Gaps = 10/101 (9%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR---TFHD-F 3337 P F+ +++ ++ +EG A F+ ++ PD VEWF K+ R+ T D + Sbjct: 231 PSFVKKMKP-SEGIEGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEETGEDQY 287 Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 +VI+D++ E++G ++CVA+N+ G+ + +A+L ++ Sbjct: 288 SLVIIDLV---TEDAGVFKCVASNEAGKITARADLTVKERQ 325 Score = 44.4 bits (100), Expect = 0.002 Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 2/82 (2%) Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840 ++QEG ++ + + P V+W K+G+P+ SS++ ++ I + +D+ Sbjct: 969 KVQEGEEISIKSVVK--AKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDS 1026 Query: 841 GSYTVRAVNKLGEAISTASIRV 862 G YT A N +G+A T S+ V Sbjct: 1027 GEYTCEATNSVGKASRTYSVEV 1048 Score = 44.0 bits (99), Expect = 0.003 Identities = 58/223 (26%), Positives = 89/223 (39%), Gaps = 43/223 (19%) Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT--LND 3749 P P F ++K + + EGG FD +++ G P ++WF R H + Sbjct: 228 PVKPSFVKKMKPSEGI-EGGEARFDVQIK--GSPKPDVEWFRGMTKITDKERFHVEETGE 284 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809 + + ID + DAG + C A+N+ G KIT A+ D+ +K Sbjct: 285 DQYSLVIIDLV-TEDAGVFKCVASNEAG------KIT--ARADLT-------------VK 322 Query: 3810 ELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869 E + I + + P++ K + E +R +PK D + WY NG Sbjct: 323 ERQFAPIFEDEQMGPVILR--------KGDELSIKETIR----AKPKPD----VNWYHNG 366 Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912 K L S SL I+ ED+GEY C A N G+ Sbjct: 367 KPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGK 409 Score = 44.0 bits (99), Expect = 0.003 Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982 L +G L ++ + K PD + WY NGK L + S +L ++ D+G Sbjct: 340 LRKGDELSIKETIRAKPKPD--VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAG 397 Query: 2983 IYTCKAYNKRGEAFTSSTV 3001 Y C+A+NK G+A + V Sbjct: 398 EYRCEAHNKLGKALRTYDV 416 Score = 44.0 bits (99), Expect = 0.003 Identities = 21/75 (28%), Positives = 41/75 (54%), Gaps = 2/75 (2%) Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705 + EG +I ++ ++ P ++W+KNG+ ++ SS+ R ++ + + + D Sbjct: 968 IKVQEGEEISIKSVVK--AKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDD 1025 Query: 706 SGEYTCRAVSATGVA 720 SGEYTC A ++ G A Sbjct: 1026 SGEYTCEATNSVGKA 1040 Score = 44.0 bits (99), Expect = 0.003 Identities = 51/213 (23%), Positives = 86/213 (40%), Gaps = 22/213 (10%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576 P ++ EG+ A V +PS+ EW + L R ++ TL + + Sbjct: 1066 PMQIIEGEDAVMTCEVTGKPEPSV--EWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILE 1123 Query: 2577 DAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQ-LKEAAMNKVPEMFVD 2635 D LY C A N G + ++ + P S E + + E + P D Sbjct: 1124 DEALYTCTASNSLGSVSSSAELQ------VDEKGVVPISPEPVSPVFEEPVKAEP----D 1173 Query: 2636 TGVQQAPIFTTHLKSYDKLVE-GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-- 2692 G AP+ D +V G+ L+A++ P ++EW K+G + R Sbjct: 1174 EGTV-APVIEG---LNDVVVPLGREAKLDARITGSPKP--EVEWIKDGQVVEDAGRFLYV 1227 Query: 2693 STFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725 + G+ +L I+ ++ +D+G Y C A N GE Sbjct: 1228 ENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260 Score = 43.6 bits (98), Expect = 0.004 Identities = 38/149 (25%), Positives = 61/149 (40%), Gaps = 10/149 (6%) Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737 T+H +T+ P P F ++K + EGG FD +V+ G P ++WF Sbjct: 846 TVHSEAMLTVR--VPVKPSFVTKLKPT-EAVEGGEARFDVKVK--GSPKPEVEWFSGTTK 900 Query: 3738 FATGSRVHTLNDFGF--IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795 A R + G +L + + D+G C ATN+ G T+ A + + + Sbjct: 901 IAEKGRFR-FEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPV 959 Query: 3796 ESQLPQGMSGEKIKELERGRISDAPKEEP 3824 QG K++E E I K +P Sbjct: 960 FEDEEQGPI--KVQEGEEISIKSVVKAKP 986 Score = 43.6 bits (98), Expect = 0.004 Identities = 21/62 (33%), Positives = 34/62 (54%) Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 V+W NGKP+K + D + + + +DSG YTC+ATN +G+A + ++ V Sbjct: 990 VKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVE 1049 Query: 1404 AK 1405 K Sbjct: 1050 KK 1051 Score = 43.2 bits (97), Expect = 0.005 Identities = 63/238 (26%), Positives = 87/238 (36%), Gaps = 35/238 (14%) Query: 3863 IEWYRNGKLLPSGHRYRTVYDMG--FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920 ++WYR + + R+ V D G SL I V DSG Y C A N+ GE +KA + Sbjct: 46 VDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELI 105 Query: 3921 CKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQ 3980 + VP + E +EA + SEV +T+ Sbjct: 106 VNDGA-----SPVPEEKIQEETAPAVEA---EKPSEV---------------APLITEPL 142 Query: 3981 SQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYP 4040 + E T EC+ G P VEW + + R D + + Sbjct: 143 KSLEVPEGATATLECKAT--GIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIG 200 Query: 4041 EDSGEYLCRATNLYGMDET--KAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQV 4096 D GEY C N +G+D T K + KP V K MK E I EA + V Sbjct: 201 TDQGEYKCMVKNDFGLDYTTAKLTVNVPVKPSFV------KKMKPSEGIEGGEARFDV 252 Score = 42.7 bits (96), Expect = 0.007 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 PQ + P+Q L + G + + LT S+ +VEW K+ + S RI S + + Sbjct: 766 PQILEPIQPL---EVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKADNDTAT 822 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 L I RAED G Y N G S A + V Sbjct: 823 LTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV 855 Score = 42.7 bits (96), Expect = 0.007 Identities = 37/148 (25%), Positives = 56/148 (37%), Gaps = 3/148 (2%) Query: 1282 EQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQT 1341 +Q + Q + D + + V P F L E VEG + +++ G Sbjct: 832 DQGVYQCVIRNDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAVEGGEARFDVKVK--GSPK 889 Query: 1342 MRVEWFCNGKPIKTGHRFR-PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400 VEWF I RFR + +L L + DSG C ATN+ G+ + L Sbjct: 890 PEVEWFSGTTKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADL 949 Query: 1401 RVIAKKDLILESQHPSGLEKIQYLEDTS 1428 V + + G K+Q E+ S Sbjct: 950 NVKERLFAPVFEDEEQGPIKVQEGEEIS 977 Score = 42.7 bits (96), Expect = 0.007 Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 5/100 (5%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGH-RYRTVYD 3883 V P F+T++K E RF+ +V K PK +EW+ K+ G R+ V + Sbjct: 857 VPVKPSFVTKLKPTEAVEGGEARFDVKV--KGSPKPEVEWFSGTTKIAEKGRFRFEEVGE 914 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 F SL + + DSG C A N+ G+ ++A ++ K+ Sbjct: 915 EQF-SLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKE 953 Score = 42.3 bits (95), Expect = 0.009 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694 P F+ +K +EGG+ F+ +I+ G P +EW + I RF + G Sbjct: 231 PSFVKKMKPSEGIEGGEARFDVQIK--GSPKPDVEWFRGMTKITDKERF-HVEETGEDQY 287 Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 SL ++ L +D+G + C A + G +A L V R Sbjct: 288 SLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKER 324 Score = 42.3 bits (95), Expect = 0.009 Identities = 24/65 (36%), Positives = 31/65 (47%) Query: 1071 SDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLS 1130 S+ VEW N ++ + RI++ D L I RAED GVY V RN G Sbjct: 791 SEQAPKVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSE 850 Query: 1131 ASMTV 1135 A +TV Sbjct: 851 AMLTV 855 Score = 42.3 bits (95), Expect = 0.009 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 2/81 (2%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 I +EG+ I + V+ P ++W N KPL ++ ++ I +D Sbjct: 968 IKVQEGEEISIKSVVKAK--PKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDD 1025 Query: 2843 SGIYTCKATNSKGSATTSGSL 2863 SG YTC+ATNS G A+ + S+ Sbjct: 1026 SGEYTCEATNSVGKASRTYSV 1046 Score = 41.1 bits (92), Expect = 0.021 Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 9/122 (7%) Query: 2143 IDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202 ++W N +++ +R ++ D L I + AED G Y C N G + L V Sbjct: 797 VEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVR 856 Query: 2203 GHRNIILDTQHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAH 2261 P+ + K++ EA +G R +V + K SP V GTT + E Sbjct: 857 -------VPVKPSFVTKLKPTEAVEGGEARFDV-KVKGSPKPEVEWFSGTTKIAEKGRFR 908 Query: 2262 FE 2263 FE Sbjct: 909 FE 910 Score = 41.1 bits (92), Expect = 0.021 Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 4/108 (3%) Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690 E + V P F T LK + VEG + +V + P ++EWF + R Sbjct: 850 EAMLTVRVPVKPSFVTKLKPTEA-VEGGEARFDVKV--KGSPKPEVEWFSGTTKIAEKGR 906 Query: 2691 LK-STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 + +L + L+ DSG C ATN G+ S A + +++R Sbjct: 907 FRFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKER 954 Score = 40.7 bits (91), Expect = 0.028 Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 5/100 (5%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885 V P F+ ++K E RF+ ++ K PK +EW+R + R+ V + G Sbjct: 227 VPVKPSFVKKMKPSEGIEGGEARFDVQI--KGSPKPDVEWFRGMTKITDKERFH-VEETG 283 Query: 3886 --FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 SL I+ + ED+G + C A N+ G+ +A ++ K+ Sbjct: 284 EDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKE 323 Score = 40.3 bits (90), Expect = 0.037 Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 10/142 (7%) Query: 1006 DIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFE 1064 D++ E G+ K +A + + R + VK Q P F G + +G + Sbjct: 293 DLVTED---AGVFKCVASNEAGKITARADLTVKERQFAPIFEDEQMGPVILRKGDELSIK 349 Query: 1065 A--RVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122 R +P+ D V WY NGK + SA + +L I S + ED+G Y A N Sbjct: 350 ETIRAKPKPD----VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHN 405 Query: 1123 AAGEAQLSASMTVETRSSIDTS 1144 G+A + + VE ++ T+ Sbjct: 406 KLGKALRTYDVRVEEQAPKGTA 427 Score = 39.9 bits (89), Expect = 0.049 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P+F+Q K+ G AK + + V W R + + ++ + +E G SL Sbjct: 17 PVFKQPLKDIIAIAGEEAKLDVIVSVGAE--VDWYRGDQAIEDKGRFMLVDDEGEGMFSL 74 Query: 132 LIKQIGPGDEGEYTCTARNQYGE 154 LI + P D G Y C A N GE Sbjct: 75 LIDDVQPSDSGMYECVAFNNAGE 97 Score = 39.9 bits (89), Expect = 0.049 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 3/99 (3%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 + V P F + + E +EG + +++ G VEWF I RF Sbjct: 225 VNVPVKPSFVKKMKPSEGIEGGEARFDVQIK--GSPKPDVEWFRGMTKITDKERFHVEET 282 Query: 1365 F-DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 D +L ++ + ED+GV+ C A+N+ G+ L V Sbjct: 283 GEDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTV 321 Score = 39.9 bits (89), Expect = 0.049 Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 9/133 (6%) Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI--TFDFGY 2299 P FV +++ + + EG A F+ Q++ P+ +E++ + RFH+ T + Y Sbjct: 231 PSFVKKMKPSEGI-EGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEETGEDQY 287 Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQR-PEGLEKIREL 2356 SL I V EDAG + A N G T+ +TV + I + Q P L K EL Sbjct: 288 -SLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKERQFAPIFEDEQMGPVILRKGDEL 346 Query: 2357 ESAEPFKRPEIPE 2369 E + P+ Sbjct: 347 SIKETIRAKPKPD 359 Score = 39.5 bits (88), Expect = 0.065 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 12/116 (10%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR--- 1894 V V P F+ ++ P++ EG A ++ +I+ P P+ VEW+ + R+ Sbjct: 225 VNVPVKPSFVKKMK-PSEGIEGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEE 281 Query: 1895 TSND-FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE--SIIRDSQ 1947 T D + +D++T ED+G + C A N G+ + L V+ ++ I D Q Sbjct: 282 TGEDQYSLVIIDLVT---EDAGVFKCVASNEAGKITARADLTVKERQFAPIFEDEQ 334 Score = 39.5 bits (88), Expect = 0.065 Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 3/97 (3%) Query: 66 PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125 P +P I ++ K + +G + + G P P V W ++ PL + +Y + Sbjct: 423 PKGTAPTILSEM-KPQQVVEGEDVMLACAVSGKPEPTVEWLKEGKPLSRDSHVRPKYEAE 481 Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162 +L K DE YTC A N G S +Q Sbjct: 482 IA--TLTFKSATLEDEALYTCVATNALGSVSSSAELQ 516 Score = 39.1 bits (87), Expect = 0.086 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 5/112 (4%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P ++P+ P+ G++ ++ L + +VEW N V R K+ D Sbjct: 766 PQILEPIQ---PLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKADNDTAT 822 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAI--VRVIERSDIVTDTQNEQAIE 1286 L I + + D G Y N G+ H+ A+ VRV + VT + +A+E Sbjct: 823 LTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAVE 874 Score = 39.1 bits (87), Expect = 0.086 Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 13/123 (10%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY----DF 2032 KP F +K E EG + + P VEW+ + + RF+ F Sbjct: 860 KPSFVTKLKPTEAVEGGEARFDVKVK--GSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQF 917 Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL--DEQRLKKIQE 2090 V D+ D+GT C ATN G+ TS ++ K L+ +EQ K+QE Sbjct: 918 SLVLTDLQLT---DSGTIKCIATNEAGK--VTSRADLNVKERLFAPVFEDEEQGPIKVQE 972 Query: 2091 LEK 2093 E+ Sbjct: 973 GEE 975 Score = 38.7 bits (86), Expect = 0.11 Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 2/97 (2%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P+F P + +G + ++ + P V W+HNG+ + + Sbjct: 328 PIFEDEQMGPVILRKGDELSIKETIRAKPKPD--VNWYHNGKPLRSAPTLDIRSRGDTHS 385 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273 L II A D GEY A N LG A + VRV E++ Sbjct: 386 LAIISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQA 422 Score = 38.7 bits (86), Expect = 0.11 Identities = 21/67 (31%), Positives = 34/67 (50%) Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799 PK V W NG P+ ++ L +L + ED+G Y C A N+LG+A+ + Sbjct: 356 PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYD 415 Query: 1800 LFVQSKA 1806 + V+ +A Sbjct: 416 VRVEEQA 422 Score = 37.9 bits (84), Expect = 0.20 Identities = 24/100 (24%), Positives = 50/100 (50%), Gaps = 6/100 (6%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFGL 2699 P F +K + +EG + Q++ P+ +EWF+ +T R ++ T + Sbjct: 231 PSFVKKMKPSEG-IEGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEETGE-DQ 286 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHW 2739 +L I L +D+G++ C A+N G+ + A + +++R + Sbjct: 287 YSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKERQF 326 Score = 37.5 bits (83), Expect = 0.26 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 5/97 (5%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F MK E A F+ ++ G PK VEW R I R + + G Sbjct: 231 PSFVKKMKPSEGIEGGEARFDVQI--KGSPKPDVEWFRGMTKITDKERFH-VEETGEDQY 287 Query: 1771 NMKYVN--PEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 ++ ++ ED+G + C A NE G+ + L V+ + Sbjct: 288 SLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKER 324 Score = 37.5 bits (83), Expect = 0.26 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 9/92 (9%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK----STHDFSYV 2831 F++ L EG F+ V+ S P ++EWF + R++ FS V Sbjct: 863 FVTKLKPTEAVEGGEARFDVKVKGSPKP--EVEWFSGTTKIAEKGRFRFEEVGEEQFSLV 920 Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 D+ T DSG C ATN G T+ L Sbjct: 921 LTDLQLT---DSGTIKCIATNEAGKVTSRADL 949 Score = 36.7 bits (81), Expect = 0.46 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 10/88 (11%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR---TTHD- 2562 KP F + + PSE EG A ++ ++ G P EW+ ++ RF T D Sbjct: 230 KPSFVKKMK-PSEGIEGGEARFDVQIK--GSPKPDVEWFRGMTKITDKERFHVEETGEDQ 286 Query: 2563 FGFVTLDINSVVANDAGLYMCKAINRAG 2590 + V +D+ V DAG++ C A N AG Sbjct: 287 YSLVIIDL---VTEDAGVFKCVASNEAG 311 Score = 36.7 bits (81), Expect = 0.46 Identities = 19/63 (30%), Positives = 28/63 (44%) Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 +V E++ P +S V EGE C V+G P+P V WL G + S + Sbjct: 417 RVEEQAPKGTAPTILSEMKPQQVVEGEDVMLACAVSGKPEPTVEWLKEGKPLSRDSHVRP 476 Query: 4160 TYD 4162 Y+ Sbjct: 477 KYE 479 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVSLDITHTYEEDSG 2844 EG F+ ++ S P +EWF + R+ + T + Y SL I ED+G Sbjct: 244 EGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEETGEDQY-SLVIIDLVTEDAG 300 Query: 2845 IYTCKATNSKGSATTSGSL 2863 ++ C A+N G T L Sbjct: 301 VFKCVASNEAGKITARADL 319 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 6/120 (5%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG-- 2432 +P F L+ + ++ G+ A FD ++ G P +VEWF I + R + + G Sbjct: 860 KPSFVTKLKPTEAVEGGE-ARFDVKV--KGSPKPEVEWFSGTTKIAEKGRF-RFEEVGEE 915 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQ 2492 S+ ++ ++ D G C A+N G+ + +G K+Q+ E+ Sbjct: 916 QFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGEE 975 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 3/89 (3%) Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561 +R+F PIF GP L +G + + P + WY NG L+ Sbjct: 323 ERQFA-PIFEDEQMGPVILRKGDELSIKETIRAKPKPDVN--WYHNGKPLRSAPTLDIRS 379 Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590 +L I S DAG Y C+A N+ G Sbjct: 380 RGDTHSLAIISAKLEDAGEYRCEAHNKLG 408 Score = 33.9 bits (74), Expect = 3.2 Identities = 16/55 (29%), Positives = 27/55 (49%) Query: 666 PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720 P + W NG+ + ++ R SL ++S ++D+GEY C A + G A Sbjct: 356 PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKA 410 Score = 33.9 bits (74), Expect = 3.2 Identities = 19/54 (35%), Positives = 25/54 (46%) Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGR 3365 P V W++NGK L L I+ E++GEY C A NKLG+ Sbjct: 356 PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGK 409 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 2/89 (2%) Query: 2504 EFEKP--IFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561 +F+ P + Q+L L G+ + + + + + EW N + +K R ++ Sbjct: 757 KFKAPAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKA 816 Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590 D TL I A D G+Y C N G Sbjct: 817 DNDTATLTIKQSRAEDQGVYQCVIRNDYG 845 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 2/92 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 PQ + P++ + E + P K+EWLKN ++ S R S +L Sbjct: 766 PQILEPIQPLEVGEDQIVKLTLTFTSEQAP--KVEWLKNNIRVKESYRIKSKADNDTATL 823 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + +D G Y C + G ++A+L V Sbjct: 824 TIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV 855 Score = 33.1 bits (72), Expect = 5.7 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 8/88 (9%) Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNG--KVLEQGS-RFKLTSDF 2966 KP ++ + + VEG + V+ K P ++EW F+G K+ E+G RF+ + Sbjct: 860 KPSFVTKLKPT-EAVEGGEARFD--VKVKGSPKPEVEW-FSGTTKIAEKGRFRFEEVGEE 915 Query: 2967 GFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 F +L L D+ DSG C A N+ G+ Sbjct: 916 QF-SLVLTDLQLTDSGTIKCIATNEAGK 942 Score = 32.3 bits (70), Expect = 9.9 Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 11/124 (8%) Query: 3591 VEWFHNGKPLLTGSRV---KTIND-FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646 VEWF + R +T D + VI+++ DAG++ C A+N G+ T Sbjct: 262 VEWFRGMTKITDKERFHVEETGEDQYSLVIIDL---VTEDAGVFKCVASNEAGKITARAD 318 Query: 3647 LQVKGRQ--GIILEPQL-PSHFKSGTE-SIQKLEETLHKREEITIEDEKPNPPRFTVEIK 3702 L VK RQ I + Q+ P + G E SI++ K + + KP T++I+ Sbjct: 319 LTVKERQFAPIFEDEQMGPVILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIR 378 Query: 3703 DNID 3706 D Sbjct: 379 SRGD 382 Score = 32.3 bits (70), Expect = 9.9 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 9/155 (5%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK--TINDFGFV 3615 P F T E A F+ ++ VEWF + R + + + F Sbjct: 861 PSFVTKLKPTEAVEGGEARFDVKV--KGSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQFS 918 Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL---EPQLPSHFKSGTE-S 3671 ++ + + D+G C ATN G+ T L VK R + E Q P + G E S Sbjct: 919 LV-LTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGEEIS 977 Query: 3672 IQKLEETLHKREEITIEDEKPNPPRFTVEIKDNID 3706 I+ + + K + +++ KP V+++ D Sbjct: 978 IKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDD 1012 >SB_29786| Best HMM Match : I-set (HMM E-Value=0) Length = 6300 Score = 202 bits (493), Expect = 6e-51 Identities = 117/404 (28%), Positives = 189/404 (46%), Gaps = 21/404 (5%) Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 +PP F K ++ E + A+FE G P P ++W R+ PIK FQI +S+L Sbjct: 3058 RPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVL 3117 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528 I + D + VA ++ G CS L+V+E +VPP F N+ +T G Sbjct: 3118 TIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDE-------AVVPPEFVRKISNIELTEG 3170 Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588 ++ R D ++TGT +V W K+ ++ R +I +D ++L+I + D+G Y C A Sbjct: 3171 EIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKA 3230 Query: 4589 INSAGEARCDAECVVS-LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647 N AG+A C E ++ +P P T+ A P E EG I F + Sbjct: 3231 TNEAGQASCYGELTITFIPV----PPHFTEEAPKIPTDFE--------EGGDITFEATVS 3278 Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707 G+P P V+W+K + I S ++ + R+ D Y+L I P+D G Y C A N G Sbjct: 3279 GRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRT 3338 Query: 4708 AKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766 + + + + P L + + V EGQ A F+ + +P+I+W + G + E Sbjct: 3339 YNIDIEASEPKGSTPQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENER 3398 Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 +EG + L I +D G + C A + G+ + +L+V Sbjct: 3399 IASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442 Score = 183 bits (446), Expect = 3e-45 Identities = 118/409 (28%), Positives = 182/409 (44%), Gaps = 25/409 (6%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD--FQIHTFSTKSI 4467 PP F ++ V E + G P P + W+++ P+ P F++ Sbjct: 2199 PPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYT 2258 Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 L+I++ D+ + A N G S N+ V + PP F +++ + Sbjct: 2259 LVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKE-----PPKFERNLKDITIAE 2313 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 G R D +VTG+ V+W NGK VQP I+ +D +L+++ SGKY CV Sbjct: 2314 GCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCV 2373 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647 A N G+ + A ++ A + P+ E L + ++ G I C++ Sbjct: 2374 AENEVGQVQSAARLHITELAIQ-------------PKFAERLTNVSISSGDTIVLECRVT 2420 Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQM-SRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 GKP P V W+K DK I+ F +R D L I P+DEG YKC+A N AG+ Sbjct: 2421 GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDT 2480 Query: 4707 AAKLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765 A+L V + N P L DI V EG +F+ + KP I W + LI P Sbjct: 2481 VAELTVAK---RGNPPFFVKELVDIDVTEGGHERFEVVVDGYPKPEIDWYKNDILIRPGP 2537 Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 F + G++ L++ + E+TG TC+A +AGQ S + + KT Sbjct: 2538 KFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKT 2586 Score = 183 bits (445), Expect = 4e-45 Identities = 103/402 (25%), Positives = 189/402 (47%), Gaps = 20/402 (4%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F ++++ V E + EVE G+P P+++W ++ +K S + T L I Sbjct: 2964 PKFLQRLELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTI 3023 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 ++D + +A+N+ G C+A L+VEE G+ PP F + ++ + G++ Sbjct: 3024 MNTTLDDEGEYTCIAKNKVGEVSCTAELLVEE-------GMRPPQFIVKPSSLQIMEGKM 3076 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 + + +V+G +V WL++G+ ++P R +I E L I++A D G+Y CVA + Sbjct: 3077 AKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATS 3136 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650 AG+ C E +V A PPE + + + + EG+ F +I G P Sbjct: 3137 KAGKDSCSVELLVD-------------EAVVPPEFVRKISNIELTEGEIARFDVRITGTP 3183 Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710 P V WYK + I+ F++ D+++L I + D G Y C A N AG+ + +L Sbjct: 3184 APEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGEL 3243 Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMI 4770 +T + P EG F+ ++ + +P ++W ++ A I E+ + + Sbjct: 3244 TITFIPVPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHYHLH 3303 Query: 4771 HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812 + L I +D+G +TC AT G + + + +++ Sbjct: 3304 RSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRTYNIDIEA 3345 Score = 162 bits (393), Expect = 7e-39 Identities = 114/411 (27%), Positives = 183/411 (44%), Gaps = 29/411 (7%) Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464 V P +PP F + ++ + E RF+V+ G P P + WY ++ I Sbjct: 2294 VAPKEPPKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDE 2353 Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524 S LI+ ++ S + VAEN G + +A L + E Q P F NV+ Sbjct: 2354 HSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHITELAIQ-------PKFAERLTNVS 2406 Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY-PQDSGK 4583 ++SG + L+ +VTG V W K+ K+++ D R G +L + P D G Sbjct: 2407 ISSGDTIVLECRVTGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGS 2466 Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643 Y+C+A N AG+ AE V+ K N PP ++ L D V EG F Sbjct: 2467 YKCIATNPAGQDDTVAELTVA------------KRGN-PPFFVKELVDIDVTEGGHERFE 2513 Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 + G P P + WYK D LI+P F + D +TL + + PE+ G C A NSAG+ Sbjct: 2514 VVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQ 2573 Query: 4704 VTVAAKLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761 + +++ + P +T L D+ + G+ + +P ++W + I Sbjct: 2574 AICSCFVQINEKTIP---PKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEIT 2630 Query: 4762 -PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 + D + H ++ VL+ +T DTG + C AG+ T++K+ VK Sbjct: 2631 NEDGVDIETSHCTSSLVLVGVDT--PDTGVYRCLVFNPAGEDSTNSKITVK 2679 Score = 161 bits (390), Expect = 2e-38 Identities = 156/619 (25%), Positives = 264/619 (42%), Gaps = 48/619 (7%) Query: 4128 ARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTGKIEVIXXX 4186 A F +TG P+P+V WL N I +G R++ DG +Y + +R D G+I+ Sbjct: 2854 AIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATN 2913 Query: 4187 XXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQ-RTETELEKTFEER----QVL 4241 L V + + + +P E + Q + E E T E Q L Sbjct: 2914 SAGTVTSMASLIVRDKPSEQTELYI---KPVGQEPVEMQFQVPFETEPTDEAGPKFLQRL 2970 Query: 4242 QRQGVID-HRPELKPKVIKEPE--TEWQQSVKRKKNEEYYNKLQELE-NEQVIKESRLRE 4297 + + V++ R +L+ +V +P+ EW + + K E + + I + L + Sbjct: 2971 ELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDD 3030 Query: 4298 STHQYAIPGDKV--TSNT----VAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPS 4351 I +KV S T V + M + ++ E ++ K + +P P Sbjct: 3031 EGEYTCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPE 3090 Query: 4352 ESTVH-GKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEH------KAQTQERVVEGP 4404 + G+ + ++ Q + E D+ + I + E E+ KA VE Sbjct: 3091 VEWLRDGRPIKPGRRFQIEFEK--DRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELL 3148 Query: 4405 VKPSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463 V + PP F +K+ + E E ARF+V G P P + WY++ PI++ F+I++ Sbjct: 3149 VDEAVVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDD 3208 Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523 K L+IR + D+ ++ A N G A C L + VPP FT A + Sbjct: 3209 DKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTITFIP-------VPPHFTEEAPKI 3261 Query: 4524 --NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581 + G + + V+G DV W K+ + + + TY+L I P DS Sbjct: 3262 PTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDS 3321 Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641 G Y C A N G A+ ++ +PK T P+ I+ ++ V EGQ Sbjct: 3322 GAYTCTATNECGMAKR----TYNIDIEASEPKGST------PQFIDLMQPVEVTEGQTAT 3371 Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701 F C + G P P+++W+K +K ++ + +L I++ +DEG+YKCVA NS Sbjct: 3372 FECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSF 3431 Query: 4702 GRVTVAAKLKVTQPDQADN 4720 G+ + A +L V + D ++ Sbjct: 3432 GKASCATELLVDEADSPED 3450 Score = 158 bits (384), Expect = 9e-38 Identities = 115/410 (28%), Positives = 191/410 (46%), Gaps = 43/410 (10%) Query: 4427 QARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAE 4486 +A FEVE G+P P ++W + + I++ F+ + T L +R ++D A Sbjct: 2853 KAIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTAT 2912 Query: 4487 NRGGTAKCSANLVVEEKRRQ---------GRGGI-----VP----------PSFTLTAQN 4522 N GT A+L+V +K + G+ + VP P F + Sbjct: 2913 NSAGTVTSMASLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRLEL 2972 Query: 4523 VNVTSGQLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581 V G L+ +V+G KP+ V WLK+G+ V+P + E +TL I+ D Sbjct: 2973 KEVVEGSRTDLEVEVSGKPKPV-VEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDE 3031 Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641 G+Y C+A N GE C AE +V + PP+ I + EG+ + Sbjct: 3032 GEYTCIAKNKVGEVSCTAELLV-------------EEGMRPPQFIVKPSSLQIMEGKMAK 3078 Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701 F ++ G P P V+W + + IKP + FQ+ D L I +A DEG+Y CVA + A Sbjct: 3079 FEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKA 3138 Query: 4702 GRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760 G+ + + +L V D+A P + + +I + EG+ A+F +IT P + W ++ Sbjct: 3139 GKDSCSVELLV---DEAVVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVP 3195 Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 I + F++ + + L+I + DTG+++C+AT AGQ +L + Sbjct: 3196 IEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTI 3245 Score = 146 bits (354), Expect = 4e-34 Identities = 90/302 (29%), Positives = 144/302 (47%), Gaps = 14/302 (4%) Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342 A F+V+++G P P+V W KN + + ++ E + TL +R ++ D G A N Sbjct: 2854 AIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATN 2913 Query: 343 PNGCIVTSGYLAV-ESPTESYVQDQRSQYITDTQQRETEERIEISEKA-----LAPQFVK 396 G + + L V + P+E Q YI Q E + ++ + P+F++ Sbjct: 2914 SAGTVTSMASLIVRDKPSE-----QTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQ 2968 Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456 + ++V EG T + V+G+P P V W + D ++ + L E H L I N T Sbjct: 2969 RLELKEVVEGSRTDLEVEVSGKPKPVVEW-LKDGELVKPSSLMTLETEGQVHTLTIMNTT 3027 Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516 L D G TC+A+NK GE + C ++ +E + P+F+ + S+L + EG+ AR G Sbjct: 3028 LDDEGEYTCIAKNKVGEVS--CTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSG 3085 Query: 517 TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 P P + W +DG PI P +I + S L I AK +D Y C A + AG + Sbjct: 3086 LPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSV 3145 Query: 577 RL 578 L Sbjct: 3146 EL 3147 Score = 143 bits (346), Expect = 4e-33 Identities = 98/306 (32%), Positives = 143/306 (46%), Gaps = 18/306 (5%) Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTY 4569 +PP F +++ V G V L VTG+ +V W K+GK V P R ++ Y Sbjct: 2198 IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257 Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629 TL+I EA D+GKY C A NSAGE V A K+ PP+ L Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKE-----------PPKFERNL 2306 Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689 KD +AEG + F ++ G P P V WY KL++P + + DE++ I P D Sbjct: 2307 KDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHD-DEHSSLILMHCPLD 2365 Query: 4690 -EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748 G Y CVA N G+V AA+L +T + A L ++ + G + ++T K Sbjct: 2366 LSGKYTCVAENEVGQVQSAARLHIT--ELAIQPKFAERLTNVSISSGDTIVLECRVTGKP 2423 Query: 4749 KPTIQWLREGALIPETPDFQM-IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807 +P + W ++ I + F G+ VL I +D G++ C AT AGQ +T A+ Sbjct: 2424 RPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAE 2483 Query: 4808 LVVKSK 4813 L V + Sbjct: 2484 LTVAKR 2489 Score = 134 bits (324), Expect = 2e-30 Identities = 128/526 (24%), Positives = 208/526 (39%), Gaps = 49/526 (9%) Query: 62 TAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR 121 TA P +P PP F+ ++ +G + G+P P V W + P+ Sbjct: 2191 TAALP-KPIPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFE 2249 Query: 122 YNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR 180 G+V +L+IK+ D G+Y C A N GE S + R Sbjct: 2250 VG-CVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVD----VLHVAPKEPPKFER 2304 Query: 181 HVSETVEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKV---DTFEYRLLREVSF 236 ++ + + T+ KV Y NG D + D +L Sbjct: 2305 NLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPL 2364 Query: 237 RESITKRYVGESDV-QISTEIDRSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPR 294 S V E++V Q+ + + ++ PK A++ N + G + +++G PR Sbjct: 2365 DLSGKYTCVAENEVGQVQSAARLHITELAIQPKFAERLTNVSISSGDTIVLECRVTGKPR 2424 Query: 295 PRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353 P+V WFK+ + + ++ T L +R D E CI T+ Sbjct: 2425 PQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDD--------EGSYKCIATN--- 2473 Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413 Q +T + ++++ P FVK D DVTEG RF+ Sbjct: 2474 -------------------PAGQDDTVAELTVAKRGNPPFFVKELVDIDVTEGGHERFEV 2514 Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH-ALMITNVTLSDSGVVTCVARNKSG 472 V G P PE+ W+ ND IR K + E G+H L++ + ++G +TC ARN +G Sbjct: 2515 VVDGYPKPEIDWYKNDILIRP--GPKFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAG 2572 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532 + C + + EK + PK +R L++ G+ V L + GTP P + W D I Sbjct: 2573 QAICSCFVQINEK--TIPPKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEIT 2630 Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + I T S+L + D Y+C N AG +T +++ Sbjct: 2631 NEDGVDIETSHCTSSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKI 2676 Score = 124 bits (300), Expect = 1e-27 Identities = 68/194 (35%), Positives = 96/194 (49%), Gaps = 3/194 (1%) Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444 + E PQF+ + EGKM +F+ RV+G P PEV W + R I+ +I E Sbjct: 3053 VEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEF-E 3111 Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504 L I + L+D G TCVA +K+G+ + C + ++ E VV P+FV + S + + E Sbjct: 3112 KDRSVLTIIDAKLNDEGEYTCVATSKAGKDS--CSVELLVDEAVVPPEFVRKISNIELTE 3169 Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 GE + R GTP P +TW KD VPI I++D +L I SD Y C Sbjct: 3170 GEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCK 3229 Query: 565 AQNVAGSTATRARL 578 A N AG + L Sbjct: 3230 ATNEAGQASCYGEL 3243 Score = 121 bits (292), Expect = 1e-26 Identities = 93/333 (27%), Positives = 153/333 (45%), Gaps = 38/333 (11%) Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299 I K VGE V + E+ G + PP+ KP + ++ EG A+F+ ++SG P P V W Sbjct: 3037 IAKNKVGE--VSCTAELLVEEG-MRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEW 3093 Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359 ++G+ + + +I + + L + + + +D G YT +A + G S L V+ Sbjct: 3094 LRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVD--- 3150 Query: 360 ESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRP 419 E+ V + + I++ IE++E G++ RFD R+TG P Sbjct: 3151 EAVVPPEFVRKISN---------IELTE------------------GEIARFDVRITGTP 3183 Query: 420 YPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCR 479 PEVTW+ ++ I D +I ++ H+L+I + LSD+G +C A N++G+ + Sbjct: 3184 APEVTWYKDEVPIEDGGRFEI-YSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGE 3242 Query: 480 LNVIEKEQVVAPKFVERFSTL--NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537 L + V P F E + + EG + A G P P + W KD PI + Sbjct: 3243 LTITFIP--VPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHY 3300 Query: 538 RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 +H +L I D+ Y CTA N G Sbjct: 3301 HLHRSNDTYSLTIRGVGPDDSGAYTCTATNECG 3333 Score = 115 bits (277), Expect = 8e-25 Identities = 107/405 (26%), Positives = 175/405 (43%), Gaps = 40/405 (9%) Query: 4419 PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVE 4476 P + E + +V G P P I W+++ + SPD I S + ++IRQ ++ Sbjct: 3975 PFEITEEGDVKLQVRICGIPFPEIDWFKDGRHL--SPDDHIKITSDDDLYTVLIRQPTIK 4032 Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKR--RQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534 D+ + + +N G A + ++ +E + R RG + +V S V D Sbjct: 4033 DTGKYKCIIKNIAGKATRTFDVDIEAVKPSRHVRGELSEHLILPKFIDVTEVSPYRVSYD 4092 Query: 4535 TKVTGTKPI----DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 T T + DV W+K+G+ ++ R I ++D + L IL A D G Y+CV N Sbjct: 4093 GDFTLTVKLSGSGDVQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTN 4152 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP--LKDKIVA----EGQAIEFSC 4644 AG D S + +P T A P E++ P L+D + A + ++ + Sbjct: 4153 KAG---FDTR---SFDIGLEDLRPHTFAYE-PSELVAPYYLEDGVTAFQMTDAGDVKLTV 4205 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 ++ GKP PTV+W K D+ + PS +F + D ++L I + D+G YK +A N G Sbjct: 4206 RVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGGIN 4265 Query: 4705 TVAAKLKV-----TQPDQADNLPALTPLRD-IVVYE---GQPAQFKTQITSKIKPTIQWL 4755 T + + T D+ A L D I YE G + ++T + PT+ W Sbjct: 4266 TKRFNVDIEWDETTTTRVVDDREAPRFLDDGISSYEFTSGGDVKLTVKVTGRPYPTVTWS 4325 Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 R+ I F M + N E+ G++ C AG Sbjct: 4326 RDDKDIKPDDTFHMFSDDENPA--------ENQGSYKCTIANEAG 4362 Score = 113 bits (273), Expect = 2e-24 Identities = 165/729 (22%), Positives = 276/729 (37%), Gaps = 72/729 (9%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169 P F+ L V V EG+ A F C V G+P+P + W NG + R TY+G + I Sbjct: 3353 PQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTI 3412 Query: 4170 PKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTET 4229 + D G + + L V A P + + + Sbjct: 3413 NQCTIDDEGNYKCVARNSFGKASCATELLV-----------DEADSPEDQVSGKIMNFDR 3461 Query: 4230 ELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQV 4289 EL++ FE + P+++ +V PE Q+ + + E+ + ++ N Sbjct: 3462 ELKRDFEAEDLFN--------PKVQVEVQMPPEG--QREITLESTEQTKPEGKQKWNPHP 3511 Query: 4290 IKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPR-IP 4348 E R Q + DK N A + N +TE +KV Q P+ P Sbjct: 3512 PAEGPQRNPYRQES--EDKPKWNPHPPVEASKSNPNPQETEFKRNPHPPQKVLQNPKGNP 3569 Query: 4349 DPSESTV------HGKEVHVAKQKQTQK----EVVGDKEITRKITSTETTEIEHKAQTQE 4398 P E+ + H E K K+ EVV D + +T T ++ Sbjct: 3570 YPHEAEIKPKWNPHPPEEMPDKAKRDSSSIPIEVVRDSDEVSFTMNTRGTGVQIIDSGTM 3629 Query: 4399 RVVEGPV---KPSKPPIFTKKMQ--PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453 R V +P K + P V E R EV G P P ++W +++ I + Sbjct: 3630 RFDTDSVLDDDDERPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIIS 3689 Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513 SP F + + + L+I +D + +A N G A + ++ VE + R V Sbjct: 3690 SPHFMVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNVEGANDEMRASFVD 3749 Query: 4514 PSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 +++T G LV L+ K+ G DV W K+ + R KI E + Sbjct: 3750 ME---DRGPLSITEDGDLV-LEVKIKGEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVT 3805 Query: 4573 ILEAYPQDSGKYECVAINSAGEA----RCDAECVV-SLPATKDKPKPQTKAANAPPEIIE 4627 I +A +DS N G A D E V+ L + + + N E + Sbjct: 3806 IKDANKEDSVFTNIT--NDFGTAIRRFSIDVESVMPKLQGFVKRDEDFPQFVNV--EGVS 3861 Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687 P ++ +EG I+ ++ G P P V W+K + P+++ D + L I P Sbjct: 3862 PF--EVTSEGD-IKLQTRVTGFPEPDVSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTP 3918 Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL---TPLRDIVVYEGQPAQFKTQI 4744 G YKCVA N G + ++ + + A+++ +R + +G A +I Sbjct: 3919 LYAGTYKCVATNRRGTNSRDFEVTIETGEAAEHITFQQDEETVRAQFIEKGPYAPVPFEI 3978 Query: 4745 TSK--IK----------PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792 T + +K P I W ++G + ++ + + +LI +DTG + Sbjct: 3979 TEEGDVKLQVRICGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYK 4038 Query: 4793 CRATTAAGQ 4801 C AG+ Sbjct: 4039 CIIKNIAGK 4047 Score = 107 bits (258), Expect = 2e-22 Identities = 92/404 (22%), Positives = 162/404 (40%), Gaps = 20/404 (4%) Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476 + P V + + G P P + W+++ P+ + H ILII+ Sbjct: 3860 VSPFEVTSEGDIKLQTRVTGFPEPDVSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPL 3919 Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN----------VT 4526 + + VA NR GT + +E T+ AQ + +T Sbjct: 3920 YAGTYKCVATNRRGTNSRDFEVTIETGEAAEHITFQQDEETVRAQFIEKGPYAPVPFEIT 3979 Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586 V+L ++ G ++ W K+G+ + PD KI +D YT+LI + +D+GKY+C Sbjct: 3980 EEGDVKLQVRICGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKC 4039 Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646 + N AG+A + + + + P+ I+ + +F+ + Sbjct: 4040 IIKNIAGKATRTFDVDIEAVKPSRHVRGELSEHLILPKFIDVTEVSPYRVSYDGDFTLTV 4099 Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 VQW K ++I+ SK + + + D + L I A +D G YKCV N AG T Sbjct: 4100 KLSGSGDVQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAGFDTR 4159 Query: 4707 AAKLKV------TQPDQADNLPALTPLRDIV----VYEGQPAQFKTQITSKIKPTIQWLR 4756 + + + T + L A L D V + + + ++ K KPT++W + Sbjct: 4160 SFDIGLEDLRPHTFAYEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRVRGKPKPTVKWTK 4219 Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 + + F ++ E + LLI + D G + AT G Sbjct: 4220 NDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGG 4263 Score = 107 bits (257), Expect = 2e-22 Identities = 95/365 (26%), Positives = 168/365 (46%), Gaps = 23/365 (6%) Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 +VE P+ K+EW N ++E G RF+ SD TL L D G C A N G Sbjct: 2857 EVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAG 2916 Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTV 3053 + +++ K + E+T+ G E ++ ++ + E +P D+ G P+F Sbjct: 2917 TVTSMASLIVRDKPS--EQTELYIKPVGQEPVE-MQFQVPFE--TEPTDEAG--PKFLQR 2969 Query: 3054 FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV-VLEILG 3112 ++ ++ EG E + +G V+EW +G+ ++ S + T+ G V L I+ Sbjct: 2970 L-ELKEVVEGSRTDLEVEV--SGKPKPVVEWLKDGELVKPS-SLMTLETEGQVHTLTIMN 3025 Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172 T D G Y+C A NK G E+S E + + + P+F +++ + +G+ A FE Sbjct: 3026 TTLDDEGEYTCIAKNKVG--EVSCTAELLVEEGMRPPQFIVKPSSLQ-IMEGKMAKFEAR 3082 Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 V + P+ +EW +G+P++ R + + VL I + +D GEY C A +K G+ Sbjct: 3083 VSGLPGPE--VEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGK 3140 Query: 3233 DFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVT 3292 D +C + V + P+ + KI +E +G + + P +T +D Sbjct: 3141 D------SCSVELLVDEAVVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEV 3194 Query: 3293 KLVEG 3297 + +G Sbjct: 3195 PIEDG 3199 Score = 101 bits (243), Expect = 1e-20 Identities = 104/423 (24%), Positives = 166/423 (39%), Gaps = 42/423 (9%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP F + + +G AKFE ++ G P P V W R P+ ++ + + + ++ Sbjct: 3059 PPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLT 3118 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSV-YIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189 ++ ++ DEGEYTC A ++ G+ CSV + E E Sbjct: 3119 IIDAKLN--DEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKISNIELTEGEIARFD 3176 Query: 190 AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE--SITKRYVGE 247 T E + +V +G D D ++R+ + + S + + E Sbjct: 3177 VRITGTPAPEVTWYKDEVPIEDGGRFEIYSD---DDKHSLVIRDCALSDTGSYSCKATNE 3233 Query: 248 S-DVQISTEIDRSLGPVSPPKIAQKPR-NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 + E+ + PV P + P+ + +EG D F+ +SG PRP V W K+ Sbjct: 3234 AGQASCYGELTITFIPVPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAP 3293 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365 + S+S HY L N + G P +S Sbjct: 3294 I------------------------SESSHYHLHRSNDTYSLTIRGV----GPDDSGAYT 3325 Query: 366 QRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424 + +R IE SE K PQF+ + Q +VTEG+ F+C V G P P + Sbjct: 3326 CTATNECGMAKRTYNIDIEASEPKGSTPQFIDLMQPVEVTEGQTATFECTVKGYPRPSIE 3385 Query: 425 WFINDRQIRDDYNHKIL-VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483 WF N +++ N +I E +L I T+ D G CVARN G+ + L V Sbjct: 3386 WFKNGLPLKE--NERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLVD 3443 Query: 484 EKE 486 E + Sbjct: 3444 EAD 3446 Score = 99.1 bits (236), Expect = 8e-20 Identities = 66/250 (26%), Positives = 109/250 (43%), Gaps = 16/250 (6%) Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465 K PP F K++ V E RFEV DG P P I WY+ + I+ P F I Sbjct: 2488 KRGNPPFFVKELVDIDVTEGGHERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDH 2547 Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525 LI++ E++ A N G A CS + + EK +PP T ++++ Sbjct: 2548 HTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKT-------IPPKITQRLHDLSI 2600 Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585 +G+ V L K GT V W + +++ + I T +L+++ D+G Y Sbjct: 2601 DAGKTVNLTVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTSSLVLVGVDTPDTGVYR 2660 Query: 4586 CVAINSAGEARCDAECVVSLPATKDKP---KPQTKAANAP----PEIIEPLKDKIVAEGQ 4638 C+ N AGE +++ +++ K +P +P + P P + + DK V E Sbjct: 2661 CLVFNPAGEDSTNSK--ITVKGVKIEPAIQEPVEAVLSLPRGEAPSFTKKITDKQVVEND 2718 Query: 4639 AIEFSCKIVG 4648 A+ ++ G Sbjct: 2719 AVRLEVEVTG 2728 Score = 97.5 bits (232), Expect = 2e-19 Identities = 98/398 (24%), Positives = 161/398 (40%), Gaps = 46/398 (11%) Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488 + V+ G P P + W R++ IK PD H FS + E+ + N Sbjct: 4309 KLTVKVTGRPYPTVTWSRDDKDIK--PDDTFHMFSDD------ENPAENQGSYKCTIANE 4360 Query: 4489 GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV-------------TSGQLVRLDT 4535 G +L V+ QG P F+ + ++ TS V + Sbjct: 4361 AGVRAKHFDLDVDW---QGPAPGHPYVFSSKKDDWHIFCDDNEDTAPFKFTSEGDVTMTV 4417 Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595 K G I W+K+ K + D + E+DG Y+L +++ +D G Y C+A + G + Sbjct: 4418 KTKGRPTIT--WMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRS 4475 Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEP---LKDKIVAEGQAIEFSCKIVGKPLP 4652 E L D P ++ + ++ EG ++ ++ GKP P Sbjct: 4476 ----ERRFDLRVEDDDTSTTILMDLVRPTFVKDDDMVPFQLTEEGD-VKLMVRVAGKPKP 4530 Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 TV W K K I + + Q+S D YTL I +DEG YKC A NS G + + + Sbjct: 4531 TVTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGIYKCTASNSVGTSSQMFDVDI 4590 Query: 4713 TQPD-----QADNLPALTPLRDIVVYE---GQPAQFKTQITSKIKPTIQWLREGALIPET 4764 D + D+ P+ D+ +E + + K KP ++W ++ P T Sbjct: 4591 KGTDWMLKSKDDDFPSFVDEDDVEAFEMTDEGSIRMTVIVRGKPKPEVKWSKDDK--PLT 4648 Query: 4765 PDFQMIHE--GNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 P+ ++ E + L+I + +D GT+ C A AG Sbjct: 4649 PNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVNRAG 4686 Score = 97.1 bits (231), Expect = 3e-19 Identities = 114/467 (24%), Positives = 182/467 (38%), Gaps = 35/467 (7%) Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKP-PIF--TKKMQPCRV 4422 K T K K I K T T +IE A R V G + P F ++ P RV Sbjct: 4032 KDTGKYKCIIKNIAGKATRTFDVDIE--AVKPSRHVRGELSEHLILPKFIDVTEVSPYRV 4089 Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFA 4482 V+ G ++W ++ I++S + I +L I +D + Sbjct: 4090 SYDGDFTLTVKLSGSGD--VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYK 4147 Query: 4483 AVAENRGGTAKCSANLVVEEKRRQG----RGGIVPPSFTLTAQNV-NVTSGQLVRLDTKV 4537 V N+ G S ++ +E+ R +V P + +T V+L +V Sbjct: 4148 CVVTNKAGFDTRSFDIGLEDLRPHTFAYEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRV 4207 Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 G V W KN + V P +L ED ++LLI + D G Y+ +A N G Sbjct: 4208 RGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGGINTK 4267 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 + T + AP + + + G ++ + K+ G+P PTV W Sbjct: 4268 RFNVDIEWDETTTTRVVDDR--EAPRFLDDGISSYEFTSGGDVKLTVKVTGRPYPTVTWS 4325 Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717 + DK IKP F M +D+ E E++G YKC N AG L V Sbjct: 4326 RDDKDIKPDDTFHM--FSDD------ENPAENQGSYKCTIANEAGVRAKHFDLDVDWQGP 4377 Query: 4718 ADNLPALTPLR--DIVVY-----EGQPAQFKTQ------ITSKIKPTIQWLREGALIPET 4764 A P + + D ++ + P +F ++ + +K +PTI W+++ +I + Sbjct: 4378 APGHPYVFSSKKDDWHIFCDDNEDTAPFKFTSEGDVTMTVKTKGRPTITWMKDEKIITQD 4437 Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 F + L + EED G +TC A T G+ E L V+ Sbjct: 4438 NKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSERRFDLRVE 4484 Score = 95.9 bits (228), Expect = 7e-19 Identities = 56/210 (26%), Positives = 90/210 (42%), Gaps = 1/210 (0%) Query: 371 ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430 I + R E+ K + P+F +D +V EG VTG P PEV WF + + Sbjct: 2179 IAEEDLRIDVEQTAALPKPIPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGK 2238 Query: 431 QIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489 + + + V G + L+I SD+G C A N +GE C ++V+ Sbjct: 2239 PVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKE 2298 Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549 PKF + + EG + + G+P P++ W +G + P + I D S+L Sbjct: 2299 PPKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLI 2358 Query: 550 IPRAKASDAAWYQCTAQNVAGSTATRARLY 579 + + Y C A+N G + ARL+ Sbjct: 2359 LMHCPLDLSGKYTCVAENEVGQVQSAARLH 2388 Score = 94.3 bits (224), Expect = 2e-18 Identities = 79/316 (25%), Positives = 131/316 (41%), Gaps = 11/316 (3%) Query: 66 PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125 P + + P F Q + +G E ++ G P PVV W K LV+ + S+ E Sbjct: 2958 PTDEAGPKFLQRLELKEVVEGSRTDLEVEVSGKPKPVVEWL-KDGELVKPS--SLMTLET 3014 Query: 126 TGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184 G V +L I DEGEYTC A+N+ GE C+ + E + + Sbjct: 3015 EGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEG 3074 Query: 185 TV---EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241 + E + G G E R + + D V T L + + Sbjct: 3075 KMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVA 3134 Query: 242 KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301 G+ + +D + V PP+ +K N +L EG A+F V+++G P P VTW+K Sbjct: 3135 TSKAGKDSCSVELLVDEA---VVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYK 3191 Query: 302 NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-SPTE 360 + + + + EI + + +L +R+ SD+G Y+ A N G G L + P Sbjct: 3192 DEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTITFIPVP 3251 Query: 361 SYVQDQRSQYITDTQQ 376 + ++ + TD ++ Sbjct: 3252 PHFTEEAPKIPTDFEE 3267 Score = 93.9 bits (223), Expect = 3e-18 Identities = 145/622 (23%), Positives = 248/622 (39%), Gaps = 80/622 (12%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV--QQGHRFKTTYDFGYV 2035 P+ + + + + G V+L T+ P V+W+ + + + G +T++ Sbjct: 2589 PKITQRLHDLSIDAGKTVNL--TVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTS-- 2644 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 +L ++ DTG Y C N GE T S + V G+ ++ ++ ++ + L + Sbjct: 2645 SLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITV---KGVKIEPAIQEPVEAVLSLPR-- 2699 Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPI-NDPHLTIDWFHNGQKIRA 2154 G+ P F +T + + E D E V ++P T D N Q R Sbjct: 2700 ----------GEAPSFTKKITD-KQVVENDAVRLEVEVTGFTHEPVFTAD---NWQTKRR 2745 Query: 2155 GHRYRTTHDFGYVAL-DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILD--- 2210 R R+ F L D+ + ++ G Y +KL A+++ + ++ Sbjct: 2746 CIRERSEFLFNNKLLSDVSFRVGKEQGKYFIPG-HKLILAISSPVFYAMFYGSMAEQKAE 2804 Query: 2211 -TQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPV 2269 T + + +L + + E + ++ + + + K A FE VE Sbjct: 2805 ITVADSDADSFMELLRYAYFDEATINEENVLGVLYLAKKYILPFLADNK-AIFE--VEIT 2861 Query: 2270 HDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSA 2329 P ++E+ N ++S RF D +L ++ +D GE A N+ G TS Sbjct: 2862 GKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSM 2921 Query: 2330 ISMTVTAKGSIISESQ-RPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNI 2388 S+ V K S +E +P G E + E++ PF+ EP P F Q L+ + + Sbjct: 2922 ASLIVRDKPSEQTELYIKPVGQEPV-EMQFQVPFET----EPTDEAGPKFLQRLE-LKEV 2975 Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448 EG + + G P VEW ++ +L++ SS +T + ++TI + +DEG Sbjct: 2976 VEGSRTDLEVEVS--GKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGE 3033 Query: 2449 YMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKP 2508 Y C A N +GE E EGM+ P + KP Sbjct: 3034 YTCIAKNKVGEVSCTA------------ELLVEEGMR---------------PPQFIVKP 3066 Query: 2509 IFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTL 2568 Q++ G + A +EARV G P EW +G +K G RF+ + L Sbjct: 3067 SSLQIMEG-------KMAKFEARV--SGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVL 3117 Query: 2569 DINSVVANDAGLYMCKAINRAG 2590 I ND G Y C A ++AG Sbjct: 3118 TIIDAKLNDEGEYTCVATSKAG 3139 Score = 93.9 bits (223), Expect = 3e-18 Identities = 91/333 (27%), Positives = 138/333 (41%), Gaps = 43/333 (12%) Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105 RPP+F V + I EG++A +EA + +G +EW +G+ I+ R + + Sbjct: 3058 RPPQFI-VKPSSLQIMEGKMAKFEARV--SGLPGPEVEWLRDGRPIKPGRRFQIEFEKDR 3114 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165 VL I+ K D G Y+C AT+K G+ SV+L VD++ P F I NIE L +G+ Sbjct: 3115 SVLTIIDAKLNDEGEYTCVATSKAGKDSCSVEL-LVDEAV-VPPEFVRKISNIE-LTEGE 3171 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 A F+ + P+ + WY + P+ R + SD L I D+G Y C+ Sbjct: 3172 IARFDVRITGTPAPE--VTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCK 3229 Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFI 3285 A N+ G+ +CYG+ + + P + E PK Sbjct: 3230 ATNEAGQ------ASCYGELTITFIPVPPHF---------------------TEEAPKIP 3262 Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDIL 3345 T + EG FEA + PD VEW + + Y L I Sbjct: 3263 TDFE------EGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDTYSLTIR 3314 Query: 3346 YCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 ++SG Y C ATN+ G N+ + E Sbjct: 3315 GVGPDDSGAYTCTATNECGMAKRTYNIDIEASE 3347 Score = 90.6 bits (215), Expect = 3e-17 Identities = 60/196 (30%), Positives = 86/196 (43%), Gaps = 7/196 (3%) Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584 VT +++ KVTG V WLK+ + V D K+ EED Y+L I E D G Y Sbjct: 4861 VTEEGDIKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMY 4920 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644 N G + V T + + + P + EG + S Sbjct: 4921 TVKITNDVGSGTRTFDVKVE-DTTTSLFEGTVRPKFIEDDSFVPFES--TEEGN-VRLSV 4976 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 KI GKP+P V W K +K + + ++ D YTL I EA P D G YKC N AG+ Sbjct: 4977 KITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKS 5036 Query: 4705 TVAAKLKV---TQPDQ 4717 T +++ T+P++ Sbjct: 5037 TRTFSVEIEGETKPEK 5052 Score = 90.2 bits (214), Expect = 4e-17 Identities = 51/178 (28%), Positives = 81/178 (45%), Gaps = 2/178 (1%) Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461 D EG F+ V+GRP P+V W ++ I + +H L + ++L I V DSG Sbjct: 3264 DFEEGGDITFEATVSGRPRPDVEWHKDEAPISES-SHYHLHRSNDTYSLTIRGVGPDDSG 3322 Query: 462 VVTCVARNKSGETAFQCRLNVIEKE-QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520 TC A N+ G +++ E + P+F++ + V EG+ G P P Sbjct: 3323 AYTCTATNECGMAKRTYNIDIEASEPKGSTPQFIDLMQPVEVTEGQTATFECTVKGYPRP 3382 Query: 521 RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 I W K+G+P+ N + +G S+L I + D Y+C A+N G + L Sbjct: 3383 SIEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATEL 3440 Score = 90.2 bits (214), Expect = 4e-17 Identities = 64/236 (27%), Positives = 107/236 (45%), Gaps = 6/236 (2%) Query: 4394 AQTQERVVEGPV-KPSKPPIF--TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP 4450 A+ ++ ++E + KP + PIF T +++P V E + V+ G+P P ++W +++ P Sbjct: 4830 ARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVTGKPKPSVEWLKDDRP 4889 Query: 4451 IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG 4510 + + ++ L IR+ D ++ N G+ + ++ VE+ G Sbjct: 4890 VLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFEG 4949 Query: 4511 IVPPSFTLTAQNVNVTSGQL--VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568 V P F V S + VRL K+TG +V W K+ K V ++ +D Sbjct: 4950 TVRPKFIEDDSFVPFESTEEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDI 5009 Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPE 4624 YTL I EA P DSG Y+C N AG++ + +K KP T+ P E Sbjct: 5010 YTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKP-TEREGKPLE 5064 Score = 89.4 bits (212), Expect = 6e-17 Identities = 60/188 (31%), Positives = 88/188 (46%), Gaps = 7/188 (3%) Query: 3047 PPEFTTVFKDI-VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105 PP FT I D EG +EA++ +G +EW + I S + Sbjct: 3251 PPHFTEEAPKIPTDFEEGGDITFEATV--SGRPRPDVEWHKDEAPISESSHYHLHRSNDT 3308 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDG 3164 L I G DSG Y+C ATN+ G A+ + ++ + KG P+F +Q +E + +G Sbjct: 3309 YSLTIRGVGPDDSGAYTCTATNECGMAKRTYNIDIEASEPKGSTPQFIDLMQPVE-VTEG 3367 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 Q+A FECTV P IEW+ NG P++ + RI + + L I D G Y C Sbjct: 3368 QTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKC 3425 Query: 3225 RAYNKYGE 3232 A N +G+ Sbjct: 3426 VARNSFGK 3433 Score = 86.6 bits (205), Expect = 4e-16 Identities = 73/311 (23%), Positives = 136/311 (43%), Gaps = 42/311 (13%) Query: 275 SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDS 333 +++ E D + +V++ G+P+P V W K+ + +I+S H ++++H TL + + + D Sbjct: 3656 AEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIISS-PHFMVSSHADVHTLVINSPNQDDI 3714 Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393 G Y ++A N G + + VE + + R+ ++ + E+R +S Sbjct: 3715 GQYKVIASNHRGMASRTFDVNVEGAND----EMRASFV------DMEDRGPLS------- 3757 Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI---------LVNE 444 + +D D+ + ++ G P P+V W+ +D + + KI + + Sbjct: 3758 ---ITEDGDLV------LEVKIKGEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVTIKD 3808 Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV--ERFSTLNV 502 + + TN+T +D G T + R + +L K P+FV E S V Sbjct: 3809 ANKEDSVFTNIT-NDFG--TAIRRFSIDVESVMPKLQGFVKRDEDFPQFVNVEGVSPFEV 3865 Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562 + L R G P P ++W KDG+P++PN + H L I A Y+ Sbjct: 3866 TSEGDIKLQTRVTGFPEPDVSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLYAGTYK 3925 Query: 563 CTAQNVAGSTA 573 C A N G+ + Sbjct: 3926 CVATNRRGTNS 3936 Score = 86.2 bits (204), Expect = 6e-16 Identities = 112/497 (22%), Positives = 197/497 (39%), Gaps = 32/497 (6%) Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767 T P T + D+ + + + + G P+ V+W + I + + Sbjct: 2586 TIPPKITQRLHDLSIDAGKTVNLTVKFF--GTPEPLVKWFMDDEEITNEDGVDIETSHCT 2643 Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827 +L + V+ D+G Y C N GE T+S + V+ + A+ + + E Sbjct: 2644 SSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKGVKIEPAIQEPVEAVLSLPRGEAP 2703 Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887 S ++ D +V N A R ++ G T + +++ + + R E+ FN K+L Sbjct: 2704 SFTKKITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQTKRRCIRE---RSEFLFNNKLL 2760 Query: 1888 QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINN-LGQAVSSIRLNVQSKESIIRDS 1946 S +R + G + G AI++ + A+ + Q E + DS Sbjct: 2761 -SDVSFRVGKEQGKYFI---------PGHKLILAISSPVFYAMFYGSMAEQKAEITVADS 2810 Query: 1947 QHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND 2006 +S +E ++Y + + A ++ V+ K + + + E +T Sbjct: 2811 DADSFMELLRY----AYFDEATINEENVLGVLYLAKKYILPFLADNKAI-FEVEIT--GK 2863 Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066 P +VEW N ++ G RF+ D L + + +D G C ATN+ G + +S Sbjct: 2864 PEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSMAS 2923 Query: 2067 VKVDAKSGLYLDTLDEQRLKKI-QELEKYERPKPIEEEQPGQR-PVFLTALTSLENLKEG 2124 + V K E +K + QE + + P E E + P FL L L+ + EG Sbjct: 2924 LIVRDKP----SEQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRL-ELKEVVEG 2978 Query: 2125 DRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMC 2184 R E VE P ++W +G+ ++ + L I+ T +D G Y C Sbjct: 2979 SRTDLE--VEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTC 3036 Query: 2185 KATNKLGEAVNTCTLKV 2201 A NK+GE T L V Sbjct: 3037 IAKNKVGEVSCTAELLV 3053 Score = 85.4 bits (202), Expect = 1e-15 Identities = 71/303 (23%), Positives = 130/303 (42%), Gaps = 31/303 (10%) Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLA 340 D + Q +++G P P V+WFK+G ++ N+H + + L +++ +G Y +A Sbjct: 3870 DIKLQTRVTGFPEPDVSWFKDGIPVV-PNEHIVYHIRDDVHILIIKSPTPLYAGTYKCVA 3928 Query: 341 ENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQD 400 N G + +E+ + +++IT Q ET I + AP ++ ++ Sbjct: 3929 TNRRGTNSRDFEVTIET-------GEAAEHITFQQDEETVRAQFIEKGPYAPVPFEITEE 3981 Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460 DV + R+ G P+PE+ WF + R + D +H + ++ + ++I T+ D+ Sbjct: 3982 GDV------KLQVRICGIPFPEIDWFKDGRHLSPD-DHIKITSDDDLYTVLIRQPTIKDT 4034 Query: 461 GVVTCVARNKSGET--AFQCRLNVIE---------KEQVVAPKFVE--RFSTLNVREGEP 507 G C+ +N +G+ F + ++ E ++ PKF++ S V Sbjct: 4035 GKYKCIIKNIAGKATRTFDVDIEAVKPSRHVRGELSEHLILPKFIDVTEVSPYRVSYDGD 4094 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 L + G+ + W KDG I + I D L I A D Y+C N Sbjct: 4095 FTLTVKLSGSGD--VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTN 4152 Query: 568 VAG 570 AG Sbjct: 4153 KAG 4155 Score = 85.0 bits (201), Expect = 1e-15 Identities = 106/507 (20%), Positives = 192/507 (37%), Gaps = 44/507 (8%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PPKI Q+ + + G V+ G P P V WF + + + N + +I T+H ++L Sbjct: 2588 PPKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTSSLV 2647 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYL---------AVESPTESYVQDQRSQY----- 370 + D+G Y L NP G T+ + A++ P E+ + R + Sbjct: 2648 LVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKGVKIEPAIQEPVEAVLSLPRGEAPSFTK 2707 Query: 371 -ITDTQQRETEE-RIEISEKALAPQFVKVCQDRDVTEGKMT-RFDCRVTGRPYPEVTWFI 427 ITD Q E + R+E+ + V + + R + + +V++ + Sbjct: 2708 KITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQTKRRCIRERSEFLFNNKLLSDVSFRV 2767 Query: 428 NDRQIRDDY-NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN----- 481 Q + HK+++ S + ++++ VA + + R Sbjct: 2768 GKEQGKYFIPGHKLILAISSPVFYAMFYGSMAEQKAEITVADSDADSFMELLRYAYFDEA 2827 Query: 482 VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541 I +E V+ ++ + L + G P P++ W K+ V I + Sbjct: 2828 TINEENVLGVLYLAKKYILPFLADNKAIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRS 2887 Query: 542 DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKV 601 DG TL + ++ D +CTA N S T + Q L++ +P Sbjct: 2888 DGTVYTLTLRGSRLDDEGEIKCTATN---SAGTVTSMASLIVRDKPSEQTELYI-KPVG- 2942 Query: 602 XXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIE 661 + + +P E P+F+ L+ +EG + E +E Sbjct: 2943 --------------QEPVEMQFQVPFETEPTDEAGPKFLQRLELKEVVEGSRTDLE--VE 2986 Query: 662 PVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAE 721 G P +EWLK+G+ ++ SS T +L +++ + D GEYTC A + G Sbjct: 2987 VSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVS 3046 Query: 722 TKAVLHVTPRATIERTSQHPETLQYIQ 748 A L V + P +LQ ++ Sbjct: 3047 CTAELLVEEGMRPPQFIVKPSSLQIME 3073 Score = 85.0 bits (201), Expect = 1e-15 Identities = 72/310 (23%), Positives = 130/310 (41%), Gaps = 28/310 (9%) Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335 ++ E D + QV++ G P P + WFK+G+ L + +I + + T+ +R D+G Sbjct: 3977 EITEEGDVKLQVRICGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGK 4036 Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395 Y + +N G + + +E+ + S+++ R E+SE + P+F+ Sbjct: 4037 YKCIIKNIAGKATRTFDVDIEAV-------KPSRHV----------RGELSEHLILPKFI 4079 Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455 V + F V +V W + D ++ +D ++ + H L I Sbjct: 4080 DVTEVSPYRVSYDGDFTLTVKLSGSGDVQW-MKDGEVIEDSKRYVIRQDDDLHMLTILGA 4138 Query: 456 TLSDSGVVTCVARNKSG--ETAFQCRLNVI-------EKEQVVAPKFVERFST-LNVREG 505 T D G CV NK+G +F L + E ++VAP ++E T + + Sbjct: 4139 TEDDLGTYKCVVTNKAGFDTRSFDIGLEDLRPHTFAYEPSELVAPYYLEDGVTAFQMTDA 4198 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 V L R G P P + W K+ P++P+ + + +L I + +D Y+ A Sbjct: 4199 GDVKLTVRVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIA 4258 Query: 566 QNVAGSTATR 575 N G R Sbjct: 4259 TNEGGINTKR 4268 Score = 84.2 bits (199), Expect = 2e-15 Identities = 61/203 (30%), Positives = 94/203 (46%), Gaps = 7/203 (3%) Query: 660 IEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719 +E G P K+EWLKN IE+ RF +L + + D GE C A ++ G Sbjct: 2858 VEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGT 2917 Query: 720 AETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDL 779 + A L V + + E+T + ++ + Q ++Q E P+F++ L +L Sbjct: 2918 VTSMASLIVRDKPS-EQTELY---IKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRL-EL 2972 Query: 780 GELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAED 839 E+ EG E +++ P VEW KDG + SS +T +L IM+ +D Sbjct: 2973 KEVVEGSRTDLEVEVSGKPKPV--VEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDD 3030 Query: 840 AGSYTVRAVNKLGEAISTASIRV 862 G YT A NK+GE TA + V Sbjct: 3031 EGEYTCIAKNKVGEVSCTAELLV 3053 Score = 83.0 bits (196), Expect = 5e-15 Identities = 57/206 (27%), Positives = 98/206 (47%), Gaps = 8/206 (3%) Query: 3029 EDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG 3088 E+ LR + Q PPEF + +DI +++EG + TG ++WF +G Sbjct: 2181 EEDLRIDVEQTAALPKPIPPEFKSALRDI-EVNEGNTVTLRIHV--TGSPKPEVDWFKDG 2237 Query: 3089 KTIEA-SHRIRTVYAFGMV-VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKG 3146 K + HR V G V L I + +D+G Y C+A N G+ S ++ + + Sbjct: 2238 KPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPK 2297 Query: 3147 QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGF 3206 + P+F ++++I + +G S F+ V P+ K+ WYHNG+ ++ + V D Sbjct: 2298 EPPKFERNLKDIT-IAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEH 2354 Query: 3207 VVLDIAYTQNHDSGEYVCRAYNKYGE 3232 L + + SG+Y C A N+ G+ Sbjct: 2355 SSLILMHCPLDLSGKYTCVAENEVGQ 2380 Score = 83.0 bits (196), Expect = 5e-15 Identities = 61/200 (30%), Positives = 91/200 (45%), Gaps = 11/200 (5%) Query: 385 ISEKALAPQFVKVCQDR--DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 +S+ P F++ + + +VTE + +VTG+P P V W +DR + D +H + Sbjct: 4841 LSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVTGKPKPSVEWLKDDRPVLSD-SHIKMT 4899 Query: 443 NESGNHALMITNVTLSDSGVVTCVARNK--SGETAFQCRLNVIEK---EQVVAPKFVE-- 495 E ++L I T SD G+ T N SG F ++ E V PKF+E Sbjct: 4900 EEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFEGTVRPKFIEDD 4959 Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555 F E V L+ + G P P ++W KD P+ +R+ TL I A Sbjct: 4960 SFVPFESTEEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATP 5019 Query: 556 SDAAWYQCTAQNVAG-STAT 574 +D+ Y+CT N AG ST T Sbjct: 5020 NDSGSYKCTLTNDAGKSTRT 5039 Score = 81.4 bits (192), Expect = 2e-14 Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 2/137 (1%) Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA-PPEIIEPLKDKIVAEGQAI 4640 G Y+ V + S G +R D V K + + + PP +PLKDK V EG+ Sbjct: 1992 GMYKVVRLRSDG-SRGDEMWVPPNVLQKKRSTAEIMMGDIQPPFFQKPLKDKEVKEGKPF 2050 Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700 + KI P V+W K + +KP +F+ R D Y L I EA EDEG Y+C A N+ Sbjct: 2051 KLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNN 2110 Query: 4701 AGRVTVAAKLKVTQPDQ 4717 AGR + A + V D+ Sbjct: 2111 AGRASTEADILVESADE 2127 Score = 80.2 bits (189), Expect = 4e-14 Identities = 58/216 (26%), Positives = 98/216 (45%), Gaps = 10/216 (4%) Query: 1722 VAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSG 1781 +A+N+A FE + G P+ +VEWL+N V IE+ +R D L ++ +D G Sbjct: 2849 LADNKAI-FEVEI--TGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEG 2905 Query: 1782 TYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVN 1841 C A N G + ++L V+ K S Q E ++ + Q ++Q + E Sbjct: 2906 EIKCTATNSAGTVTSMASLIVRDKPS----EQTELYIKPVGQEPVEMQFQVPFETEPTDE 2961 Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 P+F+ +L ++ EG E + P P VEW +G++++ + Sbjct: 2962 AGPKFLQRLE-LKEVVEGSRTDLEVEVSGKPKP--VVEWLKDGELVKPSSLMTLETEGQV 3018 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 L I+ +D GEYTC A N +G+ + L V+ Sbjct: 3019 HTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVE 3054 Score = 79.8 bits (188), Expect = 5e-14 Identities = 93/368 (25%), Positives = 152/368 (41%), Gaps = 33/368 (8%) Query: 4411 PIFTKK--MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 P F K M P ++ E + V G+P P + W +++ PI + Q+ + L Sbjct: 4499 PTFVKDDDMVPFQLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTYTL 4558 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP-PSFT--LTAQNVNV 4525 II+ +D ++ A N GT+ ++ ++ + PSF + + Sbjct: 4559 IIKSPTDKDEGIYKCTASNSVGTSSQMFDVDIKGTDWMLKSKDDDFPSFVDEDDVEAFEM 4618 Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKY 4584 T +R+ V G +V W K+ K + P+ N ++EE D TYTL+I D G Y Sbjct: 4619 TDEGSIRMTVIVRGKPKPEVKWSKDDKPLTPN-SNIVMEEMDDTYTLVIKSPSSDDRGTY 4677 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644 +C A+N AG + V T+D + + +I KD EG +I F Sbjct: 4678 KCTAVNRAG---TNIRSFVVNVNTEDSTQRDQRQM-----VIR--KD----EG-SITFE- 4721 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 + G + + D P + R D +TL I E P D G YKC + GR Sbjct: 4722 DVPGNIIRPK--FTEDGSFVPFQSTNEDRQDDTHTLTIREPSPNDTGSYKCTISSDYGRS 4779 Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764 T +++ D + PA + + +P +T +KI +Q E AL P Sbjct: 4780 TRTFNVEI-DSDMPE--PAQPDYPKVEPFHEKPLSEETMSVTKI---LQ--DEKALEPAR 4831 Query: 4765 PDFQMIHE 4772 P+ +I + Sbjct: 4832 PEKNIIED 4839 Score = 78.2 bits (184), Expect = 2e-13 Identities = 72/306 (23%), Positives = 120/306 (39%), Gaps = 34/306 (11%) Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335 K D V+ G RP +TW K+ + + NK +L V + D G Sbjct: 4406 KFTSEGDVTMTVKTKG--RPTITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGL 4463 Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395 YT +AE +G RS+ D + + + I + P FV Sbjct: 4464 YTCIAETTDG---------------------RSERRFDLRVEDDDTSTTILMDLVRPTFV 4502 Query: 396 KVCQ--DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453 K +TE + RV G+P P VTW + + I + + ++ V + + L+I Sbjct: 4503 KDDDMVPFQLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDD-TYTLIIK 4561 Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNV------IEKEQVVAPKFVER--FSTLNVREG 505 + T D G+ C A N G ++ +++ ++ + P FV+ + + Sbjct: 4562 SPTDKDEGIYKCTASNSVGTSSQMFDVDIKGTDWMLKSKDDDFPSFVDEDDVEAFEMTDE 4621 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 + + G P P + W KD P+ PN + + TL I + D Y+CTA Sbjct: 4622 GSIRMTVIVRGKPKPEVKWSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTA 4681 Query: 566 QNVAGS 571 N AG+ Sbjct: 4682 VNRAGT 4687 Score = 76.6 bits (180), Expect = 5e-13 Identities = 80/316 (25%), Positives = 133/316 (42%), Gaps = 40/316 (12%) Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336 + E D +V++ G P P V W+K+ L + + +I + + +++ K DS Sbjct: 3758 ITEDGDLVLEVKIKGEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVTIKDANKEDSVFT 3817 Query: 337 TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396 + N G + + VES V + ++ +R+ + PQFV Sbjct: 3818 NIT--NDFGTAIRRFSIDVES-----VMPKLQGFV----KRDED----------FPQFVN 3856 Query: 397 V--CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454 V +VT + RVTG P P+V+WF + + + H + H L+I + Sbjct: 3857 VEGVSPFEVTSEGDIKLQTRVTGFPEPDVSWFKDGIPVVPN-EHIVYHIRDDVHILIIKS 3915 Query: 455 VTLSDSGVVTCVARNKSGETA--FQCRLNVIEK---------EQVVAPKFVERFS----T 499 T +G CVA N+ G + F+ + E E+ V +F+E+ Sbjct: 3916 PTPLYAGTYKCVATNRRGTNSRDFEVTIETGEAAEHITFQQDEETVRAQFIEKGPYAPVP 3975 Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559 + E V L R G P P I W KDG + P+ ++I +D T+ I + D Sbjct: 3976 FEITEEGDVKLQVRICGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTG 4035 Query: 560 WYQCTAQNVAGSTATR 575 Y+C +N+AG ATR Sbjct: 4036 KYKCIIKNIAGK-ATR 4050 Score = 76.2 bits (179), Expect = 6e-13 Identities = 73/251 (29%), Positives = 107/251 (42%), Gaps = 41/251 (16%) Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735 EE L E T KP PP F ++D I+V EG V R+ G P +DWF +G Sbjct: 2181 EEDLRIDVEQTAALPKPIPPEFKSALRD-IEVNEGNTVTL--RIHVTGSPKPEVDWFKDG 2237 Query: 3736 RPFA-TGSRVHTLNDFGFI-ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793 +P + R + G + L I D G+Y C+A N G ++T S D+ Sbjct: 2238 KPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAG------EVTSSCNVDV 2291 Query: 3794 VLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRV 3853 + APKE PPKF +K T+ E RF+ +V Sbjct: 2292 ----------------------LHVAPKE------PPKFERNLKDITIAEGCSTRFDVQV 2323 Query: 3854 EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913 +PK + WY NGKL+ V+D SL +++ + SG+Y C A N+ G+ Sbjct: 2324 TGSPEPK--VFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCVAENEVGQV 2381 Query: 3914 FTKATISCKKL 3924 + A + +L Sbjct: 2382 QSAARLHITEL 2392 Score = 74.5 bits (175), Expect = 2e-12 Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 9/200 (4%) Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106 PP+F KDI I+EG ++ + TG + W++NGK ++ + V+ Sbjct: 2299 PPKFERNLKDIT-IAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHS 2355 Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166 L ++ SG Y+C A N+ GQ + + +L + + +P+F + N+ + G + Sbjct: 2356 SLILMHCPLDLSGKYTCVAENEVGQVQSAARLHITELAI--QPKFAERLTNVS-ISSGDT 2412 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV-VLDIAYTQNHDSGEYVCR 3225 EC V P ++ W+ + + +R +R + G V VL I D G Y C Sbjct: 2413 IVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCI 2470 Query: 3226 AYNKYGEDFTRATINCYGKG 3245 A N G+D T A + +G Sbjct: 2471 ATNPAGQDDTVAELTVAKRG 2490 Score = 72.9 bits (171), Expect = 6e-12 Identities = 50/156 (32%), Positives = 76/156 (48%), Gaps = 13/156 (8%) Query: 4499 VVEEKRRQGR---GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555 V+++KR G I PP F ++ V G+ +LD K+T +V WLK+G+ ++ Sbjct: 2015 VLQKKRSTAEIMMGDIQPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLK 2074 Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP--K 4613 P K TY L+I EA +D G+Y C A+N+AG A +A+ +V +P + Sbjct: 2075 PGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDE 2134 Query: 4614 PQ-----TKA---ANAPPEIIEPLKDKIVAEGQAIE 4641 PQ TK PP + L K + QA+E Sbjct: 2135 PQQMEQSTKTIAIGQEPPAVTLTLDGKAGFDFQAVE 2170 Score = 71.7 bits (168), Expect = 1e-11 Identities = 49/209 (23%), Positives = 91/209 (43%), Gaps = 10/209 (4%) Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672 KP+ + + ++P + + EG I+ + K+ GKP P+V+W K D+ + + +M+ Sbjct: 4843 KPKQEPIFIETDEVKPFE--VTEEGD-IKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMT 4899 Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV----TQPDQADNLPALTPLR 4728 D Y+L I E DEG Y N G T +KV T + P Sbjct: 4900 EEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFEGTVRPKFIEDD 4959 Query: 4729 DIVVYEGQP---AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785 V +E + +IT K P + W ++ + + + ++ H+ + L I Sbjct: 4960 SFVPFESTEEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATP 5019 Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 D+G++ C T AG+ + + ++ +T Sbjct: 5020 NDSGSYKCTLTNDAGKSTRTFSVEIEGET 5048 Score = 71.3 bits (167), Expect = 2e-11 Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 13/179 (7%) Query: 404 TEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV 463 +EG +T + GRP +TW +++ I D N + + G ++L + T D G+ Sbjct: 4409 SEGDVT-MTVKTKGRP--TITWMKDEKIITQD-NKFLFTEDDGIYSLTVVKPTEEDRGLY 4464 Query: 464 TCVARNKSGETAFQCRLNVIEKE-------QVVAPKFV--ERFSTLNVREGEPVVLNARA 514 TC+A G + + L V + + +V P FV + + E V L R Sbjct: 4465 TCIAETTDGRSERRFDLRVEDDDTSTTILMDLVRPTFVKDDDMVPFQLTEEGDVKLMVRV 4524 Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 G P P +TW KD PI +++ TL I D Y+CTA N G+++ Sbjct: 4525 AGKPKPTVTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGIYKCTASNSVGTSS 4583 Score = 70.9 bits (166), Expect = 2e-11 Identities = 72/317 (22%), Positives = 124/317 (39%), Gaps = 49/317 (15%) Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335 ++ + D + V++ G P+P V W KN + ++ S+ ++ + +L +R K+D G Sbjct: 4194 QMTDAGDVKLTVRVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGV 4253 Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395 Y ++A N G ++ D + ET + ++ AP+F+ Sbjct: 4254 YKVIATNEGGI-------------------NTKRFNVDIEWDETTTTRVVDDRE-APRFL 4293 Query: 396 KV-CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR-DDYNHKILVNESGNHALMIT 453 + T G + +VTGRPYP VTW +D+ I+ DD H + ++ N A Sbjct: 4294 DDGISSYEFTSGGDVKLTVKVTGRPYPTVTWSRDDKDIKPDDTFH--MFSDDENPA---- 4347 Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV---------------ERFS 498 + G C N++G A L+V + +V E + Sbjct: 4348 ----ENQGSYKCTIANEAGVRAKHFDLDVDWQGPAPGHPYVFSSKKDDWHIFCDDNEDTA 4403 Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558 V + + G PT ITW KD I + + D G +L + + D Sbjct: 4404 PFKFTSEGDVTMTVKTKGRPT--ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDR 4461 Query: 559 AWYQCTAQNVAGSTATR 575 Y C A+ G + R Sbjct: 4462 GLYTCIAETTDGRSERR 4478 Score = 70.9 bits (166), Expect = 2e-11 Identities = 121/610 (19%), Positives = 213/610 (34%), Gaps = 69/610 (11%) Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335 +L E D + V+++G P+P VTW K+ + + ++ ++ + TL +++ D G Sbjct: 4511 QLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGI 4570 Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395 Y A N G +S V+ ++ + + E E+++ Sbjct: 4571 YKCTASNSVG--TSSQMFDVDIKGTDWMLKSKDDDFPSFVDEDDVEAFEMTD-------- 4620 Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455 EG + R V G+P PEV W +D+ + + N ++ + L+I + Sbjct: 4621 ---------EGSI-RMTVIVRGKPKPEVKWSKDDKPLTPNSNI-VMEEMDDTYTLVIKSP 4669 Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515 + D G C A N++G +NV ++ +R + EG + Sbjct: 4670 SSDDRGTYKCTAVNRAGTNIRSFVVNVNTEDSTQRD---QRQMVIRKDEGS-ITFEDVPG 4725 Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575 P+ T +DG +P TL I +D Y+CT + G +TR Sbjct: 4726 NIIRPKFT--EDG-SFVPFQSTNEDRQDDTHTLTIREPSPNDTGSYKCTISSDYG-RSTR 4781 Query: 576 ARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGE--EDRV 633 Q P L+ + P P ED + Sbjct: 4782 TFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEETMSVTKILQDEKALEPARPEKNIIEDVL 4841 Query: 634 YPP---PQFIV--PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688 P P FI +K E G I ++ G P +EWLK+ + + + S Sbjct: 4842 SKPKQEPIFIETDEVKPFEVTEEGDIKMTVKV--TGKPKPSVEWLKDDRPVLSDSHIKMT 4899 Query: 689 FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ 748 SL + D G YT + + G T + Sbjct: 4900 EEDDIYSLTIREPTKSDEGMYTVKITNDVGSG----------------------TRTFDV 4937 Query: 749 QLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYK 808 ++ED + + ++ + + F+ P + +EG N ++T P V W K Sbjct: 4938 KVEDTTTSLFEGTVRPKFIEDDSFV-PFE---STEEG-NVRLSVKIT--GKPVPEVSWTK 4990 Query: 809 DGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868 D +P+ I +L I D+GSY N G++ T S+ + + Sbjct: 4991 DEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGET-- 5048 Query: 869 TADLGIPEQR 878 + G P +R Sbjct: 5049 KPEKGKPTER 5058 Score = 69.3 bits (162), Expect = 7e-11 Identities = 79/309 (25%), Positives = 124/309 (40%), Gaps = 41/309 (13%) Query: 768 QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827 Q P F +PL+D E++EG+ + ++T + P V+W KDG P+ + + Sbjct: 2031 QPPFFQKPLKDK-EVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXX 887 L I ED G Y AVN G A + A I V + + P+Q KT Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAI 2147 Query: 888 XXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGF-------------AHFEARLE 934 Q E K P D+I+ ++ F++ L Sbjct: 2148 GQEPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSALR 2207 Query: 935 PI----GDS-TLRV----------EWLKDGRPVEASSRITTFFNFGYV----ALTIKSVT 975 I G++ TLR+ +W KDG+PV S F G V L IK Sbjct: 2208 DIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPV--SGLPHRRFEVGCVGEVYTLVIKEAR 2265 Query: 976 VHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEE 1035 D G Y C+AYN+ G+ T+S N+ ++ +A + P ++ + A S R + Sbjct: 2266 GSDTGKYLCKAYNSAGEVTSSCNVDVLH----VAPKEPPKFERNLKDITIAEGCSTRFDV 2321 Query: 1036 EVKITQKPR 1044 +V + +P+ Sbjct: 2322 QVTGSPEPK 2330 Score = 69.3 bits (162), Expect = 7e-11 Identities = 57/206 (27%), Positives = 90/206 (43%), Gaps = 11/206 (5%) Query: 933 LEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ 992 +E G +VEWLK+ +E+ R + LT++ + D G C A N+ G Sbjct: 2858 VEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGT 2917 Query: 993 ATTSANLTIVTKKDIIAESQ-HPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKG 1051 T+ A+L + K E P G E ++ ++ T+E P+FL L+ Sbjct: 2918 VTSMASLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDE-----AGPKFLQRLE- 2971 Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV-ALDIASVRA 1110 ++VEG E VE VEW +G ++ + + T G V L I + Sbjct: 2972 LKEVVEGSRTDLE--VEVSGKPKPVVEWLKDG-ELVKPSSLMTLETEGQVHTLTIMNTTL 3028 Query: 1111 EDSGVYTVVARNAAGEAQLSASMTVE 1136 +D G YT +A+N GE +A + VE Sbjct: 3029 DDEGEYTCIAKNKVGEVSCTAELLVE 3054 Score = 69.3 bits (162), Expect = 7e-11 Identities = 51/194 (26%), Positives = 82/194 (42%), Gaps = 6/194 (3%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669 KVEW N+ ++SG RF ++ L + +D G C A N+ G + IV Sbjct: 2867 KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSMASLIV 2926 Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729 K S Q E + + Q ++Q + P F ++ V E Sbjct: 2927 RDKPS----EQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRLELKEVVEGSRTD 2982 Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789 E + G PK VEWL++G ++ S+ +T + L + +D G YTC A N Sbjct: 2983 LEVEV--SGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKN 3040 Query: 1790 ELGEAVTSSTLFVQ 1803 ++GE ++ L V+ Sbjct: 3041 KVGEVSCTAELLVE 3054 Score = 68.9 bits (161), Expect = 9e-11 Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 8/209 (3%) Query: 1862 AHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921 A +E I P+P +VEW N +++SG R+ +D L + +D GE C A Sbjct: 2854 AIFEVEITGKPEP--KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTA 2911 Query: 1922 INNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFG 1981 N+ G S L V+ K S Q E ++ + + +++ + + P+F Sbjct: 2912 TNSAGTVTSMASLIVRDKPS----EQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFL 2967 Query: 1982 KPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILY 2041 + ++ EV EG LE ++ P VEW +G V+ + L I+ Sbjct: 2968 QRLELKEVVEGSRTDLEVEVS--GKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMN 3025 Query: 2042 AYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 +D G Y C A N VGE T+ + V+ Sbjct: 3026 TTLDDEGEYTCIAKNKVGEVSCTAELLVE 3054 Score = 68.9 bits (161), Expect = 9e-11 Identities = 67/242 (27%), Positives = 107/242 (44%), Gaps = 19/242 (7%) Query: 3719 VEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778 VE G P +++W N +G R +D L + D GE C ATN G+ Sbjct: 2858 VEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGT 2917 Query: 3779 ATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE-EPIVSTPPKFITQIK 3837 T+ A + K +++L G++ E++ P E EP PKF+ +++ Sbjct: 2918 VTSMASLIVRDKPS--EQTELYIKPVGQEPVEMQ----FQVPFETEPTDEAGPKFLQRLE 2971 Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSGHRYRTVYDMGFV-SLDILYVY 3895 E EG R + VE PK +EW ++G+L+ PS T+ G V +L I+ Sbjct: 2972 --LKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSS--LMTLETEGQVHTLTIMNTT 3027 Query: 3896 AEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTS 3955 +D GEY C A N GE +SC + + P+ + + +L ME + K+ + Sbjct: 3028 LDDEGEYTCIAKNKVGE------VSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEA 3081 Query: 3956 EV 3957 V Sbjct: 3082 RV 3083 Score = 68.9 bits (161), Expect = 9e-11 Identities = 64/238 (26%), Positives = 109/238 (45%), Gaps = 17/238 (7%) Query: 2797 VEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGS 2856 VE + P K+EW N+ + SG R++ D + +L + + +D G C ATNS G+ Sbjct: 2858 VEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGT 2917 Query: 2857 ATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIP 2916 T+ SL I D Q + ++ V Q E + T+ P+++ Sbjct: 2918 VTSMASL-------IVRDKPSEQTELYIKPVGQ-EPVEMQFQVPFETEPTDEAGPKFLQR 2969 Query: 2917 IAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDV 2976 + + ++VEG LE +V K P +EW +G++++ S L ++ TL +++ Sbjct: 2970 LELK-EVVEGSRTDLEVEVSGKPKP--VVEWLKDGELVKPSSLMTLETEGQVHTLTIMNT 3026 Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRK 3034 D G YTC A NK GE V CT++ + E + P+ +Q +E + K Sbjct: 3027 TLDDEGEYTCIAKNKVGE------VSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAK 3078 Score = 68.5 bits (160), Expect = 1e-10 Identities = 54/202 (26%), Positives = 86/202 (42%), Gaps = 9/202 (4%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595 G P + EW N V ++ G RF D TL + +D G C A N AG Sbjct: 2862 GKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSM 2921 Query: 2596 XXXXXXXX-XXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKL 2654 + ++P E ++++ +VP T + P F L+ ++ Sbjct: 2922 ASLIVRDKPSEQTELYIKPVGQEPVEMQF----QVPFETEPTD-EAGPKFLQRLE-LKEV 2975 Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714 VEG LE +V + P +EW K+G + + + + + TL+I + DD G Sbjct: 2976 VEGSRTDLEVEVSGKPKP--VVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGE 3033 Query: 2715 YTCKATNLLGEAVSTASIKIED 2736 YTC A N +GE TA + +E+ Sbjct: 3034 YTCIAKNKVGEVSCTAELLVEE 3055 Score = 68.5 bits (160), Expect = 1e-10 Identities = 64/222 (28%), Positives = 92/222 (41%), Gaps = 38/222 (17%) Query: 3692 PNPPRFTVEI-KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750 P PP FT E K D EGG + F+ V G P ++W + P + S H Sbjct: 3249 PVPPHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSN 3306 Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810 +L I + D+G YTC ATN+ G A T I +E+ P+G + + I Sbjct: 3307 DTYSLTIRGVGPDDSGAYTCTATNECGMAKRTYNID--------IEASEPKGSTPQFIDL 3358 Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK 3870 ++ P +T+ ++ T E C V K P+ IEW++NG Sbjct: 3359 MQ-----------------PVEVTEGQTATFE--------CTV--KGYPRPSIEWFKNGL 3391 Query: 3871 LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912 L R + Y+ SL I +D G Y C A N FG+ Sbjct: 3392 PLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGK 3433 Score = 67.7 bits (158), Expect = 2e-10 Identities = 107/510 (20%), Positives = 193/510 (37%), Gaps = 37/510 (7%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 + E T P+ + D +SI G + + G V+W D + + Sbjct: 2582 INEKTIPPKITQRLHD-LSIDAGKTVNLTVKF--FGTPEPLVKWFMDDEEITNEDGVDIE 2638 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021 + +L + V D G Y C +N G+ +T++ +T+ K A + + + Sbjct: 2639 TSHCTSSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKGVKIEPAIQEPVEAVLSLP 2698 Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081 E S K T+++V R + G + +++ + + + E+ F Sbjct: 2699 RGEAPSFTKKITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQTK---RRCIRERSEFLF 2755 Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141 N K ++ + Y + A S V+ + + E + A +TV + Sbjct: 2756 NNKLLSDVSFRVGKEQGKYFIPGHKLILAISSPVFYAMFYGSMAEQK--AEITVADSDAD 2813 Query: 1142 DTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRL 1201 + R Y I E + +Y ++ ++ P +++ K I + Sbjct: 2814 SFMELLRYAYFDEATINEENVLGVLYLAKK-------YILPF-----LADNKAIF---EV 2858 Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261 E G P +VEW N + G RF+ D L + + D GE A N G+ Sbjct: 2859 EITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTV 2918 Query: 1262 HTSAIVRVIERSDIVTDTQNEQAIEQIQLL-EDAARRTKQV--REDITVMQAPQFSRALH 1318 + A S IV D +EQ I+ + ++ QV + T P+F + L Sbjct: 2919 TSMA-------SLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRLE 2971 Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378 E VEG+ LE + G VEW +G+ +K E L +++ + Sbjct: 2972 LKEVVEGSRTDLEVEVS--GKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLD 3029 Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408 D G YTC A N++GE SC ++ ++ + Sbjct: 3030 DEGEYTCIAKNKVGE--VSCTAELLVEEGM 3057 Score = 67.7 bits (158), Expect = 2e-10 Identities = 109/498 (21%), Positives = 182/498 (36%), Gaps = 46/498 (9%) Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748 +EK PP+ T + D + + G V+ V+ G P + WF + V Sbjct: 2583 NEKTIPPKITQRLHD-LSIDAGKTVNLT--VKFFGTPEPLVKWFMDDEEITNEDGVDIET 2639 Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808 +L + + D G Y C N G +T +KIT + + +E + + + E + Sbjct: 2640 SHCTSSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITV---KGVKIEPAIQEPV--EAV 2694 Query: 3809 KELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEP-KEDPKLRIE-WY 3866 L RG P F +I V E++ VR E V +P + W Sbjct: 2695 LSLPRGEA-------------PSFTKKITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQ 2741 Query: 3867 RNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926 + + R +++ +S D+ + ++ G+Y + + Sbjct: 2742 TKRRCIRE--RSEFLFNNKLLS-DVSFRVGKEQGKYFIPGHKLILA--ISSPVFYAMFYG 2796 Query: 3927 IILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLV 3986 + + + + S+A + ME Y E + E+++ V + + ++ Sbjct: 2797 SMAEQKAEITVADSDADSFMELLRYAYFDEATINEENVLGVLYLAKKYILPFLADNKAIF 2856 Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEY 4046 E+E T G P KVEW N + +RF P D + +D GE Sbjct: 2857 EVEIT---------GKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEI 2907 Query: 4047 LCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESK 4106 C ATN G + A + KP Q ++K + + +E +QV E E Sbjct: 2908 KCTATNSAGTVTSMASLIVRDKPS----EQTELYIKPVGQ-EPVEMQFQVPFET---EPT 2959 Query: 4107 ARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH 4166 P F+ + V EG V+G PKP V WL +G + S L +G H Sbjct: 2960 DEAGPKFLQRLELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVH 3019 Query: 4167 -FDIPKTRQYDTGKIEVI 4183 I T D G+ I Sbjct: 3020 TLTIMNTTLDDEGEYTCI 3037 Score = 66.5 bits (155), Expect = 5e-10 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 4/89 (4%) Query: 69 PSPPIF-EQIFK-NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126 P PP F E+ K F +GG+ FE + G P P V W + +AP+ E + Y + + T Sbjct: 3249 PVPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHYHLHRSNDT 3308 Query: 127 GDVSLLIKQIGPGDEGEYTCTARNQYGEA 155 SL I+ +GP D G YTCTA N+ G A Sbjct: 3309 --YSLTIRGVGPDDSGAYTCTATNECGMA 3335 Score = 66.1 bits (154), Expect = 7e-10 Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%) Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034 ++ P F KP+K+ EV EG P L+ +T + P V+W +G P++ G FKT Sbjct: 2030 IQPPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071 L I A ED G Y C+A N G A T + + V++ Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVES 2124 Score = 66.1 bits (154), Expect = 7e-10 Identities = 70/265 (26%), Positives = 112/265 (42%), Gaps = 43/265 (16%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP F PLK EG + +I + P ++WLK+G+ ++ F + Sbjct: 2032 PPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTYF 2089 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-------TPRATIERTSQHPETLQYIQ 748 L + +++D G Y C AV+ G A T+A + V P ++ Q +T+ Q Sbjct: 2090 LIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAIGQ 2149 Query: 749 Q-------LE-----DYS----KYQHQESIEE--------QTSQRPQFIRP-----LQDL 779 + L+ D+ K H + I E QT+ P+ I P L+D+ Sbjct: 2150 EPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSALRDI 2209 Query: 780 GELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA-SSRITSIFNFGYV-SLNIMHLRA 837 E+ EG +T P V+W+KDG+P++ R + G V +L I R Sbjct: 2210 -EVNEGNTVTLRIHVT--GSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARG 2266 Query: 838 EDAGSYTVRAVNKLGEAISTASIRV 862 D G Y +A N GE S+ ++ V Sbjct: 2267 SDTGKYLCKAYNSAGEVTSSCNVDV 2291 Score = 65.7 bits (153), Expect = 9e-10 Identities = 65/267 (24%), Positives = 101/267 (37%), Gaps = 28/267 (10%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550 P F + V+EG+P L+ + P + W KDG P+ P + G L I Sbjct: 2033 PFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLII 2092 Query: 551 PRAKASDAAWYQCTAQNVAGSTATRAR-LYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXX 609 P A D Y+C A N AG +T A L + + + TK Sbjct: 2093 PEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAIGQEPP 2152 Query: 610 XXXXYL--------RHVERARPYIPP-GEED--------RVYPPP---QFIVPLKSVTAM 649 L + VE P+ EED P P +F L+ + Sbjct: 2153 AVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSALRDIEVN 2212 Query: 650 EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEA-SSRFTSIFRFGYI-SLDMLSLNIQDSG 707 EG + RI G P +++W K+G+ + R + G + +L + D+G Sbjct: 2213 EGNTV--TLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTG 2270 Query: 708 EYTCRAVSATGVAETKA---VLHVTPR 731 +Y C+A ++ G + VLHV P+ Sbjct: 2271 KYLCKAYNSAGEVTSSCNVDVLHVAPK 2297 Score = 64.1 bits (149), Expect = 3e-09 Identities = 40/117 (34%), Positives = 56/117 (47%), Gaps = 1/117 (0%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 +A+ +AI F +I GKP P V+W K D LI+ F+ YTL + + +DEG+ Sbjct: 2849 LADNKAI-FEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEI 2907 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750 KC A NSAG VT A L V + P+ V F+T+ T + P Sbjct: 2908 KCTATNSAGTVTSMASLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDEAGP 2964 Score = 64.1 bits (149), Expect = 3e-09 Identities = 60/215 (27%), Positives = 89/215 (41%), Gaps = 16/215 (7%) Query: 788 AHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847 A FE ++T +P +VEW K+ I + R + +L + R +D G A Sbjct: 2854 AIFEVEITGKPEP--KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTA 2911 Query: 848 VNKLGEAISTASIRVAARSTVTADLGI-PEQRRYIEKTXXXXXXXXXXXXXXXXXVPEST 906 N G S AS+ V + + +L I P + +E P+ Sbjct: 2912 TNSAGTVTSMASLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDEAG----PKFL 2967 Query: 907 QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966 Q+ E K + EG E +E G VEWLKDG V+ SS +T Sbjct: 2968 QRLELK-------EVVEGSRTDLE--VEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQV 3018 Query: 967 VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 LTI + T+ D G YTC A N +G+ + +A L + Sbjct: 3019 HTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLV 3053 Score = 64.1 bits (149), Expect = 3e-09 Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 3/103 (2%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 IE EPK S P+F+ +L V EG+TA FEC V+ P+ IE++ NG L+ R Sbjct: 3343 IEASEPKGSTPQFI-DLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERI 3399 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 T++ SL I C +D G Y A N+ G + A + V Sbjct: 3400 ASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442 Score = 62.9 bits (146), Expect = 6e-09 Identities = 33/83 (39%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PPQFIV S+ MEG FE R+ G P ++EWL++G+ I+ RF F Sbjct: 3059 PPQFIVKPSSLQIMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSV 3116 Query: 696 LDMLSLNIQDSGEYTCRAVSATG 718 L ++ + D GEYTC A S G Sbjct: 3117 LTIIDAKLNDEGEYTCVATSKAG 3139 Score = 62.9 bits (146), Expect = 6e-09 Identities = 61/216 (28%), Positives = 86/216 (39%), Gaps = 36/216 (16%) Query: 2376 PVFTQPLQNID-NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 P FT+ I + +EG F+ + G P VEW ++E I +SS Sbjct: 3252 PHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDTY 3309 Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494 S+TI V +D G Y C A+N G I +E P+G Sbjct: 3310 SLTIRGVGPDDSGAYTCTATNECG--------MAKRTYNIDIEASEPKG----------- 3350 Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554 P F ++ P E+ EGQ A +E V PS+ EW+ NG+ LK Sbjct: 3351 -----------STPQFIDLMQ-PVEVTEGQTATFECTVKGYPRPSI--EWFKNGLPLKEN 3396 Query: 2555 SRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 R +T++ +L IN +D G Y C A N G Sbjct: 3397 ERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFG 3432 Score = 62.9 bits (146), Expect = 6e-09 Identities = 33/98 (33%), Positives = 55/98 (56%), Gaps = 3/98 (3%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P+FI L P +++EGQ+A +EC ++ YP P+ +EW+ NG L+ R ++ + ++ Sbjct: 3353 PQFI-DLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSS 3409 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 L I +D G Y C A N+ G+A + L V +S Sbjct: 3410 LTINQCTIDDEGNYKCVARNSFGKASCATELLVDEADS 3447 Score = 62.5 bits (145), Expect = 8e-09 Identities = 61/198 (30%), Positives = 86/198 (43%), Gaps = 15/198 (7%) Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397 G +VEW N I++G RF P + L L +D G C ATN G VTS Sbjct: 2862 GKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAG-TVTS 2920 Query: 1398 CALRVIAKKDLILESQH--PSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIEN 1455 A ++ K + P G E ++ +T+ DE+ P+F+ R ++ Sbjct: 2921 MASLIVRDKPSEQTELYIKPVGQEPVEMQFQVP--FETEPTDEA---GPKFLQR-LELKE 2974 Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV-ALDIIDLIAEDS 1514 V+EG E +E VEW K+G+ V + G V L I++ +D Sbjct: 2975 VVEGSRTDLE--VEVSGKPKPVVEWLKDGELVK-PSSLMTLETEGQVHTLTIMNTTLDDE 3031 Query: 1515 GIYTCRAVNLVGTDEVSC 1532 G YTC A N VG EVSC Sbjct: 3032 GEYTCIAKNKVG--EVSC 3047 Score = 62.5 bits (145), Expect = 8e-09 Identities = 61/233 (26%), Positives = 101/233 (43%), Gaps = 41/233 (17%) Query: 2104 QPGQRPV-FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162 + G RP F+ +SL+ + EG A FE RV + P ++W +G+ I+ G R++ Sbjct: 3054 EEGMRPPQFIVKPSSLQ-IMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEF 3110 Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQ 2222 + L I+ D G Y C AT+K G+ ++C++++ ++ P + KI Sbjct: 3111 EKDRSVLTIIDAKLNDEGEYTCVATSKAGK--DSCSVELLVDEAVV----PPEFVRKI-- 3162 Query: 2223 LEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282 + IE+ E +I+ RF + GT P + +Y + Sbjct: 3163 -------SNIELTEGEIA--RFDVRITGT--------------------PAPEVTWYKDE 3193 Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335 ++ RF I D SL I+ C D G YS KA N G + +T+T Sbjct: 3194 VPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTIT 3246 Score = 62.5 bits (145), Expect = 8e-09 Identities = 56/220 (25%), Positives = 96/220 (43%), Gaps = 38/220 (17%) Query: 2241 PPRFVTEL-RGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY 2299 PP F E + T EG FE V P+ +E++ + + ++ +H+ Sbjct: 3251 PPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDT 3308 Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359 SL I+ P+D+G Y+ A N G ++ ++E++ Sbjct: 3309 YSLTIRGVGPDDSGAYTCTATNECGMAKRTYNI----------------------DIEAS 3346 Query: 2360 EPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI 2419 EP + P+ + +PV + EGQTA F+C + G P +EWF+N + Sbjct: 3347 EP--KGSTPQFIDLMQPV---------EVTEGQTATFECTV--KGYPRPSIEWFKNGLPL 3393 Query: 2420 EDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 +++ RI T++ S+TI+ +DEG Y C A N G+ Sbjct: 3394 KENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGK 3433 Score = 61.7 bits (143), Expect = 1e-08 Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 4/199 (2%) Query: 2665 QVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724 +VE P K+EW KN V + +G R + D + TL++ R DD G C ATN G Sbjct: 2857 EVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAG 2916 Query: 2725 EAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIV 2784 S AS+ + D+ E L+ + + + F+ L Sbjct: 2917 TVTSMASLIVRDKPSEQTE-LYIKPVGQ-EPVEMQFQVPFETEPTDEAGPKFLQRLELKE 2974 Query: 2785 CKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSG 2844 EG E VE S P +EW + + + + + +L I +T +D G Sbjct: 2975 VVEGSRTDLE--VEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEG 3032 Query: 2845 IYTCKATNSKGSATTSGSL 2863 YTC A N G + + L Sbjct: 3033 EYTCIAKNKVGEVSCTAEL 3051 Score = 61.7 bits (143), Expect = 1e-08 Identities = 103/457 (22%), Positives = 176/457 (38%), Gaps = 76/457 (16%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G+P V W ++ VP++ + R+ + + +K N EDS +T N+ G A+ Sbjct: 3772 GEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVTIKDANKEDS-VFT-NITNDFGTAIRR 3829 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857 ++ V ES + K+Q +R ED VN + P +++ Sbjct: 3830 FSIDV------------ESVMPKLQGF-----VKRDEDFPQFVN------VEGVSPFEVT 3866 Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHR-YRTSNDFGFAALDILT-VYGEDS 1914 + R+ +P+P+ V W+ +G V+ + H Y +D + T +Y + Sbjct: 3867 SEGDIKLQTRVTGFPEPD--VSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLY---A 3921 Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974 G Y C A N G + +++ E A E I + +D+ + F+ Sbjct: 3922 GTYKCVATNRRGTNSRDFEVTIETGE----------AAEHITFQQDEETVRA-----QFI 3966 Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034 + P P E+TE V L+ + + P ++W+ +GR + K T D Sbjct: 3967 EKGPYAPVPF---EITEEGDVKLQVRICGI--PFPEIDWFKDGRHLSPDDHIKITSDDDL 4021 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094 + I +DTG Y C N G+A T V + + + R + + E Sbjct: 4022 YTVLIRQPTIKDTGKYKCIIKNIAGKATRTFDVDI--------EAVKPSRHVRGELSEHL 4073 Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154 PK I+ +T ++ +GD ++ D + W +G+ I Sbjct: 4074 ILPKFID----------VTEVSPYRVSYDGDFT-LTVKLSGSGD----VQWMKDGEVIED 4118 Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191 RY D L IL +D GTY C TNK G Sbjct: 4119 SKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAG 4155 Score = 61.7 bits (143), Expect = 1e-08 Identities = 73/317 (23%), Positives = 122/317 (38%), Gaps = 36/317 (11%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 PK S + D F + + + V W K+G+ + +S ++ I + L + Sbjct: 4076 PKFIDVTEVSPYRVSYDGDFTLTVKLSGSGDVQWMKDGEVIEDSKRYVIRQDDDLHMLTI 4135 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 + D G Y + N G S + +E ++ Y E E+ Sbjct: 4136 LGATEDDLGTYKCVVTNKAGFDTRSFDIGLED-----LRPHTFAY----------EPSEL 4180 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 V Q D + K+T RV G+P P V W ND + + +L+ E Sbjct: 4181 VAPYYLEDGVTAFQMTDAGDVKLT---VRVRGKPKPTVKWTKNDEPVVPSSHFSVLM-ED 4236 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE----QVV----APKFVER- 496 +L+I + +D GV +A N+ G + +++ E +VV AP+F++ Sbjct: 4237 DVFSLLIRKPSKTDKGVYKVIATNEGGINTKRFNVDIEWDETTTTRVVDDREAPRFLDDG 4296 Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556 S+ G V L + G P P +TW +D I P+ + +D A Sbjct: 4297 ISSYEFTSGGDVKLTVKVTGRPYPTVTWSRDDKDIKPDDTFHMFSD--------DENPAE 4348 Query: 557 DAAWYQCTAQNVAGSTA 573 + Y+CT N AG A Sbjct: 4349 NQGSYKCTIANEAGVRA 4365 Score = 61.3 bits (142), Expect = 2e-08 Identities = 86/346 (24%), Positives = 143/346 (41%), Gaps = 52/346 (15%) Query: 3403 SMVRRKDTSVEEEKG--KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460 +++++K ++ E G + P F PL + E ++EG+ + ++T + N+K W +G Sbjct: 2014 NVLQKKRSTAEIMMGDIQPPFFQKPLKDKE-VKEGKPFKLDVKITALPEANVK--WLKDG 2070 Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIIL 3520 + LK G F+T L I ED G Y C A NN G A T A + V+ Sbjct: 2071 EPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSE 2130 Query: 3521 ESQLPKGMEGTIDKIA----------ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILS 3570 P+ ME + IA L+G +G D E + +P E + + Sbjct: 2131 PEDEPQQMEQSTKTIAIGQEPPAVTLTLDGKAG-FDFQAVELKIPHPDEIAEEDLRIDVE 2189 Query: 3571 ENSS------AHFECRL--IPVNDS---SMRVEWFHNGKP----LLTGSRVKTINDFGFV 3615 + ++ F+ L I VN+ ++R+ + KP G V + F Sbjct: 2190 QTAALPKPIPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFE 2249 Query: 3616 ILEIGGVYQ--------RDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKS 3667 + +G VY D G Y CKA N GE T SC + V + + P+ P F+ Sbjct: 2250 VGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDV-----LHVAPKEPPKFER 2304 Query: 3668 GTESIQKLEETLHKREEITIEDEKPNPPRF------TVEIKDNIDV 3707 + I + E R ++ + P P F V+ +D++D+ Sbjct: 2305 NLKDI-TIAEGCSTRFDVQVTG-SPEPKVFWYHNGKLVQPRDHVDI 2348 Score = 61.3 bits (142), Expect = 2e-08 Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 3/96 (3%) Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339 EPPKF ++D+T + EG S F+ ++ P+ KV W++NGK + HD Sbjct: 2298 EPPKFERNLKDIT-IAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDDEH 2354 Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375 L +++C + SG+Y CVA N++G+ + A L T Sbjct: 2355 SSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHIT 2390 Score = 61.3 bits (142), Expect = 2e-08 Identities = 63/230 (27%), Positives = 96/230 (41%), Gaps = 16/230 (6%) Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371 P+ KVEW N + G R+ D + L + ++ GE +C ATN G ++ A+ Sbjct: 2864 PEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSMAS 2923 Query: 3372 LKCTSKENLILDSQL-PRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIE 3430 L K + + + P G E +E +T +E G P F L ++ Sbjct: 2924 LIVRDKPSEQTELYIKPVGQE-------PVEMQFQVPFETEPTDEAG--PKFLQRL-ELK 2973 Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDS 3490 + EG E + + P VEW +G+ +K S + L I T +D Sbjct: 2974 EVVEGSRTDLEVEV--SGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDE 3031 Query: 3491 GEYLCRAYNNYGEAVTTASMKV-QGKR--NIILESQLPKGMEGTIDKIAA 3537 GEY C A N GE TA + V +G R I++ + MEG + K A Sbjct: 3032 GEYTCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEA 3081 Score = 60.9 bits (141), Expect = 2e-08 Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 14/145 (9%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 PQF ++ EVTEG E T+ P+ +EW+ NG P+++ R +TY+ +L Sbjct: 3353 PQFIDLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSL 3410 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK-------SGLYLDTLDEQRLKKIQE 2090 I +D G Y C A N+ G+A + + VD SG ++ ++ LK+ E Sbjct: 3411 TINQCTIDDEGNYKCVARNSFGKASCATELLVDEADSPEDQVSGKIMNF--DRELKRDFE 3468 Query: 2091 LEKYERPK-PIEEEQP--GQRPVFL 2112 E PK +E + P GQR + L Sbjct: 3469 AEDLFNPKVQVEVQMPPEGQREITL 3493 Score = 60.5 bits (140), Expect = 3e-08 Identities = 64/257 (24%), Positives = 105/257 (40%), Gaps = 38/257 (14%) Query: 1154 TRHIEESKFVEPMYQ----IEEI---SKSKPVFVQPLSNPP-PVSEGKNIHLECRLEPMG 1205 T+ +++ K +EP IE++ K +P+F++ P V+E +I + ++ G Sbjct: 4818 TKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVT--G 4875 Query: 1206 DPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265 P VEW + R V S K + +L I T +D G YTV+ N +GS + Sbjct: 4876 KPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTF 4935 Query: 1266 IVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEG 1325 V+V D T L + R K + +D V E+ E Sbjct: 4936 DVKV---EDTTTS------------LFEGTVRPKFIEDDSFV-----------PFESTEE 4969 Query: 1326 TNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTC 1385 NV L ++ G V W + KP+ R ++ D L + P DSG Y C Sbjct: 4970 GNVRLSVKI--TGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKC 5027 Query: 1386 QATNQLGEAVTSCALRV 1402 TN G++ + ++ + Sbjct: 5028 TLTNDAGKSTRTFSVEI 5044 Score = 59.3 bits (137), Expect = 8e-08 Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 8/120 (6%) Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367 M+ PQF +++ +EG E R+ G VEW +G+PIK G RF+ +E D Sbjct: 3057 MRPPQFIVKPSSLQIMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRRFQIEFEKDR 3114 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427 L ++ D G YTC AT++ G+ SC++ ++ + ++ P + KI +E T Sbjct: 3115 SVLTIIDAKLNDEGEYTCVATSKAGK--DSCSVELLVDEAVV----PPEFVRKISNIELT 3168 Score = 59.3 bits (137), Expect = 8e-08 Identities = 55/174 (31%), Positives = 75/174 (43%), Gaps = 15/174 (8%) Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601 S +V+ L EA PPEF S++ L+E A F+ R+ + V W+ + P+ Sbjct: 3142 SCSVELLVDEAVV--PPEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIE 3197 Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL 3661 G R + +D L I D G Y+CKATN G+A SC G I P + Sbjct: 3198 DGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA--SC----YGELTITFIP-V 3250 Query: 3662 PSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVE-IKDNIDVPEGGPVH 3714 P HF TE K+ + +IT E PR VE KD + E H Sbjct: 3251 PPHF---TEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHYH 3301 Score = 59.3 bits (137), Expect = 8e-08 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%) Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034 V P+F + I N E+TEG + +T P V WY + P++ G RF+ D Sbjct: 3153 VVPPEFVRKISNIELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIYSDDDK 3210 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEA 2061 +L I DTG+Y CKATN G+A Sbjct: 3211 HSLVIRDCALSDTGSYSCKATNEAGQA 3237 Score = 58.8 bits (136), Expect = 1e-07 Identities = 67/224 (29%), Positives = 108/224 (48%), Gaps = 43/224 (19%) Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296 PK PP+F L+ T + EG + F+ QV +P ++ +YHNGK +Q R H+ Sbjct: 2296 PK-EPPKFERNLKDIT-IAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQP--RDHV--- 2346 Query: 2297 FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIREL 2356 DI H +D E+S L HC + ++ K + ++E++ + ++ Sbjct: 2347 ------DIVH---DD--EHSSLI---LMHCP----LDLSGKYTCVAENE-------VGQV 2381 Query: 2357 ESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNE 2416 +SA R I E + P F + L N+ +I G T +CR+ G P +V WF+++ Sbjct: 2382 QSAA---RLHITELAIQ--PKFAERLTNV-SISSGDTIVLECRV--TGKPRPQVAWFKDD 2433 Query: 2417 KLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 K I SR + +T +TI V +DEG Y C A+N G+ Sbjct: 2434 KEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQ 2477 Score = 58.8 bits (136), Expect = 1e-07 Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 3/98 (3%) Query: 61 ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120 I A P + S P F + + +G A FE ++G P P + W + PL E + + Sbjct: 3343 IEASEP-KGSTPQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIAS 3401 Query: 121 RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158 Y SL I Q DEG Y C ARN +G+A C+ Sbjct: 3402 TYEGALS--SLTINQCTIDDEGNYKCVARNSFGKASCA 3437 Score = 58.4 bits (135), Expect = 1e-07 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 17/169 (10%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 +I + K + P+F +++ ++V EG F+C V+ G P I+WF NG P R Sbjct: 3342 DIEASEPKGSTPQF-IDLMQPVEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENER 3398 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803 + + + +L I+ D G Y C A N +G A+ ++ +V E+ P+ Sbjct: 3399 IASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATEL-------LVDEADSPEDQ 3451 Query: 3804 SGEKIKELERGRISD-------APKEEPIVSTPPKFITQIKSHTVEESE 3845 KI +R D PK + V PP+ +I + E+++ Sbjct: 3452 VSGKIMNFDRELKRDFEAEDLFNPKVQVEVQMPPEGQREITLESTEQTK 3500 Score = 58.4 bits (135), Expect = 1e-07 Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712 ++ EGQ E V+ P+ IEWFKNG+ L R+ ST++ L +L+IN DD Sbjct: 3363 EVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDE 3420 Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736 G Y C A N G+A + +++ Sbjct: 3421 GNYKCVARNSFGKASCATELLVDE 3444 Score = 58.0 bits (134), Expect = 2e-07 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 3/91 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P+F+ +P S++ ++EG+ FE ++ + +VEW ++G+P+ G RF+ + Sbjct: 3060 PQFIVKPSSLQ-IMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEFEKDRSV 3116 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 L IID D G YTC A + G D S L Sbjct: 3117 LTIIDAKLNDEGEYTCVATSKAGKDSCSVEL 3147 Score = 58.0 bits (134), Expect = 2e-07 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 3/100 (3%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E+ PEF I + I + EG A F+ R+ G V W KD P+E R + Sbjct: 3149 VDEAVVPPEFVRKISN-IELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIY 3205 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 + +L I+ + D G Y+C+A N GQA+ LTI Sbjct: 3206 SDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTI 3245 Score = 58.0 bits (134), Expect = 2e-07 Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 3/98 (3%) Query: 3275 STPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334 S P P+FI +Q V ++ EGQ+A FE + P +EWF NG L R + Sbjct: 3346 SEPKGSTPQFIDLMQPV-EVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIAST 3402 Query: 3335 HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 ++ + L I C ++ G Y+CVA N G+ S L Sbjct: 3403 YEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATEL 3440 Score = 58.0 bits (134), Expect = 2e-07 Identities = 57/221 (25%), Positives = 85/221 (38%), Gaps = 31/221 (14%) Query: 1984 IKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAY 2043 +K EVTE + + +T P VEW + RPV K T + +L I Sbjct: 4856 VKPFEVTEEGDIKMTVKVT--GKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPT 4913 Query: 2044 AEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDEQRLKKIQELEKYERPKPIEE 2102 D G Y K TN VG T VKV D + L+ T+ RPK IE+ Sbjct: 4914 KSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFEGTV---------------RPKFIED 4958 Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162 + + E+ +EG + V+ P + W + + + R H Sbjct: 4959 D----------SFVPFESTEEG---NVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDH 5005 Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203 L I DSG+Y C TN G++ T ++++ G Sbjct: 5006 QDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEG 5046 Score = 57.6 bits (133), Expect = 2e-07 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 3/100 (3%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E + P+F + I EG A FEAR+ + VEWL+DGRP++ R Sbjct: 3053 VEEGMRPPQFIVK-PSSLQIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIE 3109 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 F LTI ++D G YTC A + G+ + S L + Sbjct: 3110 FEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLV 3149 Score = 57.6 bits (133), Expect = 2e-07 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 2/97 (2%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F M+ + V E Q A FE + G P+ +EW +NG+P++ + R+ + ++ +L Sbjct: 3353 PQFIDLMQPVEVTEGQTATFECTV--KGYPRPSIEWFKNGLPLKENERIASTYEGALSSL 3410 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807 + +D G Y C A N G+A ++ L V S Sbjct: 3411 TINQCTIDDEGNYKCVARNSFGKASCATELLVDEADS 3447 Score = 57.6 bits (133), Expect = 2e-07 Identities = 79/343 (23%), Positives = 140/343 (40%), Gaps = 50/343 (14%) Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS-------LQLESQHESALQ--- 1819 L ++ +P D+G+Y C ++ G + + + + S ++E HE L Sbjct: 4755 LTIREPSPNDTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEET 4814 Query: 1820 ----KIQQLE---DSSRYQRR--EDVEVAVNQAPRFI-TQLNGPTKLSEGQSAHYECRIE 1869 KI Q E + +R ++ EDV Q P FI T P +++E ++ Sbjct: 4815 MSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVT 4874 Query: 1870 PYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929 P P+ VEW + + + S + + + +L I D G YT K N++G Sbjct: 4875 GKPKPS--VEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGT 4932 Query: 1930 SSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEV 1989 + + V+ + S E + + ++DDSFV P ++ E Sbjct: 4933 RTFDVKVEDTTT----SLFEGTVR-----------PKFIEDDSFV--------PFESTE- 4968 Query: 1990 TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGT 2049 EG+ V L +T P V W + +PV + + + L I A D+G+ Sbjct: 4969 -EGN-VRLSVKIT--GKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGS 5024 Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092 Y C TN G++ T SV+++ ++ E+ K ++E E Sbjct: 5025 YKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEE 5067 Score = 56.8 bits (131), Expect = 4e-07 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 15/140 (10%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 Q P F P+KD V E + + ++ + P+ V+WL++G P++ + T Sbjct: 2031 QPPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTY 2088 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828 L + + ED G Y C A+N G A T + + V+S A E + E QQ+E S+ Sbjct: 2089 FLIIPEADVEDEGRYRCEAVNNAGRASTEADILVES-ADEGSEPEDEP-----QQMEQST 2142 Query: 1829 RYQRREDVEVAVNQAPRFIT 1848 + +A+ Q P +T Sbjct: 2143 K-------TIAIGQEPPAVT 2155 Score = 56.8 bits (131), Expect = 4e-07 Identities = 49/176 (27%), Positives = 72/176 (40%), Gaps = 8/176 (4%) Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV-VLEILGTKTT 3116 V IS G E + TG + WF + K I R G V VL I G Sbjct: 2405 VSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPD 2462 Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176 D G+Y C ATN GQ + +L +G P F + +I+ + +G FE VV Sbjct: 2463 DEGSYKCIATNPAGQDDTVAELTVA--KRGNPPFFVKELVDID-VTEGGHERFE--VVVD 2517 Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 P +I+WY N +R + L + + ++G+ C+A N G+ Sbjct: 2518 GYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQ 2573 Score = 56.8 bits (131), Expect = 4e-07 Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 4/121 (3%) Query: 3039 QPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR 3098 + + G P+F + + V+++EGQ A +E ++ G IEWF NG ++ + RI Sbjct: 3344 EASEPKGSTPQFIDLMQP-VEVTEGQTATFECTV--KGYPRPSIEWFKNGLPLKENERIA 3400 Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158 + Y + L I D G Y C A N +G+A + +L VD++ + + + I N Sbjct: 3401 STYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATEL-LVDEADSPEDQVSGKIMNF 3459 Query: 3159 E 3159 + Sbjct: 3460 D 3460 Score = 56.4 bits (130), Expect = 5e-07 Identities = 65/256 (25%), Positives = 108/256 (42%), Gaps = 35/256 (13%) Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 PP F +K V+E + + + ++ P+ ++W ++G+ L G ++T Sbjct: 2032 PPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTYF 2089 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRS-------- 3940 L I ED G Y C AVN+ G T+A I + + P+ M++S Sbjct: 2090 LIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAIGQ 2149 Query: 3941 --EALT---------QMEATIKKYTSEVYLTEDDL-YDVDKKQ--PPRFVTQIQSQTSLV 3986 A+T +A K + E+DL DV++ P + +S + Sbjct: 2150 EPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSALRDI 2209 Query: 3987 EM-ETTKFECQLAPVGDPNMKVEWFFNGKPL--LHKNRFTPIYDFGYVAMNFGWVYPE-- 4041 E+ E ++ G P +V+WF +GKP+ L RF + G V + V E Sbjct: 2210 EVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRF----EVGCVGEVYTLVIKEAR 2265 Query: 4042 --DSGEYLCRATNLYG 4055 D+G+YLC+A N G Sbjct: 2266 GSDTGKYLCKAYNSAG 2281 Score = 56.4 bits (130), Expect = 5e-07 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Query: 2100 IEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158 IE +P G P F+ + +E + EG A FEC V+ P +I+WF NG ++ R Sbjct: 3343 IEASEPKGSTPQFIDLMQPVE-VTEGQTATFECTVKGY--PRPSIEWFKNGLPLKENERI 3399 Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193 +T++ +L I +D G Y C A N G+A Sbjct: 3400 ASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKA 3434 Score = 56.0 bits (129), Expect = 7e-07 Identities = 27/87 (31%), Positives = 46/87 (52%) Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785 PL+D V EG+P + +IT+ + ++WL++G + F+ G+ L+I Sbjct: 2038 PLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLIIPEADV 2097 Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812 ED G + C A AG+ T A ++V+S Sbjct: 2098 EDEGRYRCEAVNNAGRASTEADILVES 2124 Score = 56.0 bits (129), Expect = 7e-07 Identities = 29/108 (26%), Positives = 55/108 (50%), Gaps = 2/108 (1%) Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304 + E D++I E +L PP+ R+ ++ EG ++ ++G+P+P V WFK+G+ Sbjct: 2179 IAEEDLRIDVEQTAALPKPIPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGK 2238 Query: 305 RL--INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 + + + E+ TL ++ + SD+G Y A N G + +S Sbjct: 2239 PVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSS 2286 Score = 56.0 bits (129), Expect = 7e-07 Identities = 70/248 (28%), Positives = 102/248 (41%), Gaps = 23/248 (9%) Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRA 3497 A FE +T +P KVEW N +++G RF D L + + +D GE C A Sbjct: 2854 AIFEVEITGKPEP--KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTA 2911 Query: 3498 YNNYGEAVTTASMKVQGKRNIILESQL-PKGMEGTIDKIAALEGYSGTVDTLTPEAESGN 3556 N+ G + AS+ V+ K + E + P G E +E P E+G Sbjct: 2912 TNSAGTVTSMASLIVRDKPSEQTELYIKPVGQE-------PVEMQFQVPFETEPTDEAG- 2963 Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV- 3615 P+F + E S E + VEW +G+ L+ S + T+ G V Sbjct: 2964 -PKFLQRLELKEVVEGSRTDLEVEV--SGKPKPVVEWLKDGE-LVKPSSLMTLETEGQVH 3019 Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675 L I D G YTC A N+ GE VSC ++ ++ E P F S+Q + Sbjct: 3020 TLTIMNTTLDDEGEYTCIAKNKVGE--VSCTAEL-----LVEEGMRPPQFIVKPSSLQIM 3072 Query: 3676 EETLHKRE 3683 E + K E Sbjct: 3073 EGKMAKFE 3080 Score = 55.6 bits (128), Expect = 9e-07 Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 3/101 (2%) Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895 + VA + P+F L T ++EG S ++ ++ P+P +V WY NGK++Q Sbjct: 2292 LHVAPKEPPKFERNLKDIT-IAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHVDI 2348 Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 +D ++L ++ + SG+YTC A N +GQ S+ RL++ Sbjct: 2349 VHDDEHSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389 Score = 55.6 bits (128), Expect = 9e-07 Identities = 63/229 (27%), Positives = 87/229 (37%), Gaps = 39/229 (17%) Query: 636 PPQFI--VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693 PP F P EGG I FE + G P +EW K+ I SS + Sbjct: 3251 PPHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDT 3308 Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753 SL + + DSG YTC A + G+A+ T IE + T Q+I + Sbjct: 3309 YSLTIRGVGPDDSGAYTCTATNECGMAKR------TYNIDIEASEPKGSTPQFIDLM--- 3359 Query: 754 SKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI 813 Q E E QT A FE + P+ +EW+K+G P+ Sbjct: 3360 ---QPVEVTEGQT---------------------ATFECTVKGYPRPS--IEWFKNGLPL 3393 Query: 814 TASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 + RI S + SL I +D G+Y A N G+A + V Sbjct: 3394 KENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442 Score = 55.6 bits (128), Expect = 9e-07 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 4/93 (4%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 PQF + +E EG EC ++ G +EWF NG P+K R YE +L Sbjct: 3353 PQFIDLMQPVEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENERIASTYEGALSSL 3410 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 + +D G Y C A N G+A SCA ++ Sbjct: 3411 TINQCTIDDEGNYKCVARNSFGKA--SCATELL 3441 Score = 55.2 bits (127), Expect = 1e-06 Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 4/95 (4%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYV 1368 P+F AL +IE EG V L R+ G V+WF +GKP+ RF + Sbjct: 2200 PEFKSALRDIEVNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 L + D+G Y C+A N GE +SC + V+ Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVL 2292 Score = 55.2 bits (127), Expect = 1e-06 Identities = 28/98 (28%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 + P F +KDI +AE + F+ ++ G P+ +V W NG ++ + + +HD + Sbjct: 2298 EPPKFERNLKDITIAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHS 2355 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806 +L + + + SG YTC A NE+G+ +++ L + A Sbjct: 2356 SLILMHCPLDLSGKYTCVAENEVGQVQSAARLHITELA 2393 Score = 55.2 bits (127), Expect = 1e-06 Identities = 52/167 (31%), Positives = 74/167 (44%), Gaps = 13/167 (7%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 E+ +E E PP+F V+ ++ + EG F+ RV G P ++W +GRP G R Sbjct: 3050 ELLVE-EGMRPPQFIVK-PSSLQIMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRR 3105 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803 + L I D GEYTC AT+K G K +CS + +V E+ +P Sbjct: 3106 FQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAG------KDSCSVEL-LVDEAVVPPEF 3158 Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850 KI +E A + I TP +T K V +G RFE Sbjct: 3159 V-RKISNIELTEGEIARFDVRITGTPAPEVTWYKDE-VPIEDGGRFE 3203 Score = 55.2 bits (127), Expect = 1e-06 Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 3/97 (3%) Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE 1628 +VDE P + N+E+ EG+ A F+ R+ +V WY + P++ G RF Sbjct: 3148 LVDEAVVP-PEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEI 3204 Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG 1665 ++ +L I C D+G+Y+C+A N G+A G Sbjct: 3205 YSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYG 3241 Score = 55.2 bits (127), Expect = 1e-06 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748 DE PP F +I NI++ EG FD R+ G P + W+ + P G R + Sbjct: 3150 DEAVVPPEFVRKIS-NIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYS 3206 Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786 D +L I D G Y+C+ATN+ G A+ ++T Sbjct: 3207 DDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELT 3244 Score = 54.8 bits (126), Expect = 2e-06 Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 4/94 (4%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ--QGHRFKTTYDFGYV 2035 P+F +++ EV EG+ V L +T P V+W+ +G+PV RF+ Sbjct: 2200 PEFKSALRDIEVNEGNTVTLRIHVT--GSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 L I A DTG Y+CKA N+ GE ++ +V V Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDV 2291 Score = 54.8 bits (126), Expect = 2e-06 Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P+F + + + EG A FE ++ G +EW K+G P++ + RI + + + Sbjct: 3353 PQF-IDLMQPVEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENERIASTYEGALSS 3409 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 LTI T+ D G+Y C A N+ G+A+ + L + Sbjct: 3410 LTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442 Score = 54.4 bits (125), Expect = 2e-06 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP+F LK +T EG F+ ++ G P K+ W NG+ ++ + + S Sbjct: 2299 PPKFERNLKDITIAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSS 2356 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732 L ++ + SG+YTC A + G ++ A LH+T A Sbjct: 2357 LILMHCPLDLSGKYTCVAENEVGQVQSAARLHITELA 2393 Score = 54.4 bits (125), Expect = 2e-06 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E + E+ + PQFI L ++ EG+ A FEA+++ + P VEW +DGRPI R Sbjct: 3050 ELLVEEGMRPPQFIVKPSSL-QIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRF 3106 Query: 820 TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853 F L I+ + D G YT A +K G+ Sbjct: 3107 QIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGK 3140 Score = 54.4 bits (125), Expect = 2e-06 Identities = 32/88 (36%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 FI + + EG FEC V+ P+ IEWF N PL R ST++ + SL I Sbjct: 3355 FIDLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSLTI 3412 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 +D G Y C A NS G A+ + L Sbjct: 3413 NQCTIDDEGNYKCVARNSFGKASCATEL 3440 Score = 54.4 bits (125), Expect = 2e-06 Identities = 98/473 (20%), Positives = 180/473 (38%), Gaps = 68/473 (14%) Query: 1738 GDPKLRVEWLRNGVPIEASNRL-TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796 G PK V W ++ PI ++ + +++D Y + +K +D G Y C A N +G T Sbjct: 4526 GKPKPTVTWTKDSKPITETDHIQVSVYDDTYTLI-IKSPTDKDEGIYKCTASNSVG---T 4581 Query: 1797 SSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856 SS +F ++ + + K + +D + +DVE ++ Sbjct: 4582 SSQMF-------DVDIKGTDWMLKSKD-DDFPSFVDEDDVEA---------------FEM 4618 Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGE 1916 ++ S + P P V+W + K L L I + +D G Sbjct: 4619 TDEGSIRMTVIVRGKPKP--EVKWSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGT 4676 Query: 1917 YTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVE 1976 Y C A+N G + S +NV +++S RD Q + + K D+ + Sbjct: 4677 YKCTAVNRAGTNIRSFVVNVNTEDSTQRD-QRQMVIRK---------------DEGSITF 4720 Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 + G I+ +G V ++T D T + R + D G Sbjct: 4721 EDVPGNIIRPKFTEDGSFVPFQSTNEDRQDDTHTLT-----------IREPSPNDTGSYK 4769 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA--KSGLYLDTLDEQRLKKIQELEKY 2094 I Y T T+ + + + E KV+ + L +T+ ++ + ++ + Sbjct: 4770 CTISSDYGRSTRTFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEETMSVTKILQDEKALEP 4829 Query: 2095 ERPKP--IEE--EQPGQRPVFLTA--LTSLENLKEGDRAHFECRVEPINDPHLTIDWFHN 2148 RP+ IE+ +P Q P+F+ + E +EGD + V+ P +++W + Sbjct: 4830 ARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGD---IKMTVKVTGKPKPSVEWLKD 4886 Query: 2149 GQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + + + + T + +L I D G Y K TN +G T +KV Sbjct: 4887 DRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKV 4939 Score = 54.0 bits (124), Expect = 3e-06 Identities = 50/196 (25%), Positives = 89/196 (45%), Gaps = 19/196 (9%) Query: 2055 TNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPV---F 2111 T A+G+ ++ +D K+G + E ++ E+ + + +E+ +P+ F Sbjct: 2144 TIAIGQEPPAVTLTLDGKAGFDFQAV-ELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEF 2202 Query: 2112 LTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDFGYV-AL 2169 +AL +E + EG+ R+ P +DWF +G+ + HR G V L Sbjct: 2203 KSALRDIE-VNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTL 2259 Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE-AQGH 2228 I D+G Y+CKA N GE ++C + V H + + P ++ + A+G Sbjct: 2260 VIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVL-H---VAPKEPPKFERNLKDITIAEGC 2315 Query: 2229 STRIEVE-----EPKI 2239 STR +V+ EPK+ Sbjct: 2316 STRFDVQVTGSPEPKV 2331 Score = 54.0 bits (124), Expect = 3e-06 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 2/97 (2%) Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612 E PP+F PS L + E A FE R+ + VEW +G+P+ G R + + Sbjct: 3055 EGMRPPQFIVKPSSLQIMEGKMAKFEARVSGL--PGPEVEWLRDGRPIKPGRRFQIEFEK 3112 Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 +L I D G YTC AT++ G+ + S +L V Sbjct: 3113 DRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLV 3149 Score = 54.0 bits (124), Expect = 3e-06 Identities = 33/85 (38%), Positives = 44/85 (51%), Gaps = 3/85 (3%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 P F +SNIE L EGE A F+ R+T T P +V WY + ++ G RF + D Sbjct: 3156 PEFVRKISNIE-LTEGEIARFDVRITGTPAP--EVTWYKDEVPIEDGGRFEIYSDDDKHS 3212 Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEA 3504 L I D+G Y C+A N G+A Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQA 3237 Score = 54.0 bits (124), Expect = 3e-06 Identities = 115/502 (22%), Positives = 188/502 (37%), Gaps = 74/502 (14%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 V W KDG PV + I L IKS T AG Y C A N G + +TI Sbjct: 3885 VSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLYAGTYKCVATNRRGTNSRDFEVTIE 3944 Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062 T + E I + +D + T I + P P + I E Sbjct: 3945 TGE----------AAEHITFQQD-----EETVRAQFIEKGPYAPVPFE----ITEEGDVK 3985 Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122 + R+ ++W+ +G+ ++ + I+ D + I +D+G Y + +N Sbjct: 3986 LQVRI--CGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKN 4043 Query: 1123 AAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQP 1182 AG+A + + +E ++ S RG E + H+ KF++ + E+S Sbjct: 4044 IAGKATRTFDVDIE---AVKPSRHVRG--ELSEHLILPKFID----VTEVS--------- 4085 Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242 P VS + L +L GD V+W +G + R+ D L I+ A Sbjct: 4086 ---PYRVSYDGDFTLTVKLSGSGD----VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGA 4138 Query: 1243 TSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVR 1302 T D G Y N G S + + D+ T A E +L+ + Sbjct: 4139 TEDDLGTYKCVVTNKAGFDTRSFDIGL---EDLRPHT---FAYEPSELV-----APYYLE 4187 Query: 1303 EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPA 1362 + +T Q + +V L R++ G V+W N +P+ F Sbjct: 4188 DGVTAFQ------------MTDAGDVKLTVRVR--GKPKPTVKWTKNDEPVVPSSHFSVL 4233 Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422 E D +L + D GVY ATN+ G + + V + D ++ E + Sbjct: 4234 MEDDVFSLLIRKPSKTDKGVYKVIATNEGG--INTKRFNVDIEWDETTTTRVVDDREAPR 4291 Query: 1423 YLED-TSRYKKTDIIDESVTIK 1443 +L+D S Y+ T D +T+K Sbjct: 4292 FLDDGISSYEFTSGGDVKLTVK 4313 Score = 53.6 bits (123), Expect = 4e-06 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 10/142 (7%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR-PAYEFDYVA 1369 P+F+ L N+ G + LECR+ G +V WF + K I+ RF D Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCV 2453 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK-------KDLILESQHPSGLEKIQ 1422 L + V P+D G Y C ATN G+ T L V + K+L+ G E+ + Sbjct: 2454 LTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGNPPFFVKELVDIDVTEGGHERFE 2513 Query: 1423 YLEDTSRYKKTDIIDESVTIKP 1444 + D + D + I+P Sbjct: 2514 VVVDGYPKPEIDWYKNDILIRP 2535 Score = 53.6 bits (123), Expect = 4e-06 Identities = 44/199 (22%), Positives = 83/199 (41%), Gaps = 8/199 (4%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 G PP F DI D++EG H ++ G I+W+ N I + Sbjct: 2490 GNPPFFVKELVDI-DVTEG--GHERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGD 2546 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 L + + ++G +C+A N GQA S ++ +K+ P+ T + ++ + G Sbjct: 2547 HHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTI--PPKITQRLHDLS-IDAG 2603 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 ++ + TV P+ ++W+ + + + + + + L + D+G Y C Sbjct: 2604 KTVNL--TVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTSSLVLVGVDTPDTGVYRC 2661 Query: 3225 RAYNKYGEDFTRATINCYG 3243 +N GED T + I G Sbjct: 2662 LVFNPAGEDSTNSKITVKG 2680 Score = 53.6 bits (123), Expect = 4e-06 Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 ++I+EK + P+ + D + GK + G P P V WF++D +I ++ I Sbjct: 2580 VQINEKTIPPKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEITNEDGVDIET 2639 Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 + + +L++ V D+GV C+ N +GE + ++ V Sbjct: 2640 SHCTS-SLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITV 2678 Score = 53.6 bits (123), Expect = 4e-06 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Query: 87 GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146 GN + K+ G P P VSWT+ + P+ + ++R + Q +L I++ P D G Y C Sbjct: 4970 GNVRLSVKITGKPVPEVSWTKDEKPVHKIQ--NIRLDHQDDIYTLTIREATPNDSGSYKC 5027 Query: 147 TARNQYGEAICSVYIQPEG 165 T N G++ + ++ EG Sbjct: 5028 TLTNDAGKSTRTFSVEIEG 5046 Score = 53.2 bits (122), Expect = 5e-06 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 2/85 (2%) Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 PP+FI + S + E + +FE RV P+ +EW R+G+ + G R++ ++ Sbjct: 3059 PPQFIVKPSSLQIMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEFEKDRSV 3116 Query: 3889 LDILYVYAEDSGEYICRAVNDFGED 3913 L I+ D GEY C A + G+D Sbjct: 3117 LTIIDAKLNDEGEYTCVATSKAGKD 3141 Score = 53.2 bits (122), Expect = 5e-06 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 3/91 (3%) Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763 DE + P F + +I + E + A F+ R+ G P V W ++ VPIE R Sbjct: 3150 DEAVVP-PEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYS 3206 Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794 D +L ++ D+G+Y+C+A NE G+A Sbjct: 3207 DDDKHSLVIRDCALSDTGSYSCKATNEAGQA 3237 Score = 52.8 bits (121), Expect = 7e-06 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P+FI + + ++ EG+ A +E R+ P P VEW +G+ ++ G R++ + + Sbjct: 3060 PQFIVKPSS-LQIMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEFEKDRSV 3116 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 L I+ D GEYTC A + G+ S+ L V Sbjct: 3117 LTIIDAKLNDEGEYTCVATSKAGKDSCSVELLV 3149 Score = 52.8 bits (121), Expect = 7e-06 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 3/95 (3%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E + ++ P+F+R + ++ EL EG A F+ ++T P V WYKD PI R Sbjct: 3146 ELLVDEAVVPPEFVRKISNI-ELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRF 3202 Query: 820 TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEA 854 + SL I D GSY+ +A N+ G+A Sbjct: 3203 EIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA 3237 Score = 52.8 bits (121), Expect = 7e-06 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 5/149 (3%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F+ ++NI EG+ F+ + + P ++ W+ + P+ G R++ D SL I Sbjct: 3158 FVRKISNIELTEGEIARFDVRITGT--PAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVI 3215 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTG-DKNIYFDTQHPQGKAGLEAVEQAEEAR 2894 D+G Y+CKATN G A+ G L T +F + P+ E Sbjct: 3216 RDCALSDTGSYSCKATNEAGQASCYGELTITFIPVPPHFTEEAPKIPTDFEEGGDITFEA 3275 Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923 G RP PD E+ K E I ++ + L Sbjct: 3276 TVSG-RPR-PDVEWHKDEAPISESSHYHL 3302 Score = 52.4 bits (120), Expect = 9e-06 Identities = 56/198 (28%), Positives = 81/198 (40%), Gaps = 15/198 (7%) Query: 3590 RVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 +VEW N + +G R + +D L + G D G C ATN G T L V Sbjct: 2867 KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSMASLIV 2926 Query: 3650 KGRQGIILEPQLPSHFKS-GTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVP 3708 + + Q + K G E ++ + + E DE P+F ++ +V Sbjct: 2927 RDKP----SEQTELYIKPVGQEPVEMQFQVPFETEP---TDEA--GPKFLQRLELK-EVV 2976 Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI-ALDIDYIYARDAGE 3767 EG D VE G P ++W +G S + TL G + L I D GE Sbjct: 2977 EGS--RTDLEVEVSGKPKPVVEWLKDGE-LVKPSSLMTLETEGQVHTLTIMNTTLDDEGE 3033 Query: 3768 YTCRATNKWGSATTTAKI 3785 YTC A NK G + TA++ Sbjct: 3034 YTCIAKNKVGEVSCTAEL 3051 Score = 52.4 bits (120), Expect = 9e-06 Identities = 40/145 (27%), Positives = 69/145 (47%), Gaps = 9/145 (6%) Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340 PP+F+ +I ++ +L EG+ A F+ R+ P+ V W+ + + G R+ + D Sbjct: 3155 PPEFVRKISNI-ELTEGEIARFDVRITGTPAPE--VTWYKDEVPIEDGGRFEIYSDDDKH 3211 Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCT---SKENLILDS-QLPRGMEGGLEK 3396 L I C ++G Y C ATN+ G+ S L T + ++ ++P E G + Sbjct: 3212 SLVIRDCALSDTGSYSCKATNEAGQASCYGELTITFIPVPPHFTEEAPKIPTDFEEGGD- 3270 Query: 3397 LQTLEDSMVRRKDTSVEEEKGKAPV 3421 T E ++ R VE K +AP+ Sbjct: 3271 -ITFEATVSGRPRPDVEWHKDEAPI 3294 Score = 52.0 bits (119), Expect = 1e-05 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 PQF + ++ EG EA ++ + P VEW +GRP++ G RF+ ++ L Sbjct: 3060 PQFIVKPSSLQIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEFEKDRSVL 3117 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 I+ A D G Y C AT+ G+ + + VD Sbjct: 3118 TIIDAKLNDEGEYTCVATSKAGKDSCSVELLVD 3150 Score = 52.0 bits (119), Expect = 1e-05 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 2/84 (2%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P+F R + NIE EG + R+ G V W+ + PI+ G RF + D +L Sbjct: 3156 PEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSL 3213 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEA 1394 + D+G Y+C+ATN+ G+A Sbjct: 3214 VIRDCALSDTGSYSCKATNEAGQA 3237 Score = 52.0 bits (119), Expect = 1e-05 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 3/84 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P F + + NI+ + EG+ A FD R+ G P +V W+++E IED R D S Sbjct: 3156 PEFVRKISNIE-LTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHS 3212 Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459 + I D G Y C+A+N G+ Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQ 3236 Score = 52.0 bits (119), Expect = 1e-05 Identities = 86/336 (25%), Positives = 124/336 (36%), Gaps = 54/336 (16%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 V WF +G P++ + IL I AG Y C ATNR G T S +V Sbjct: 3885 VSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLYAGTYKCVATNRRG--TNSRDFEVT 3942 Query: 3651 GRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEG 3710 G E H + Q+ EET+ + IE P F ++ E Sbjct: 3943 IETGEAAE-----HI-----TFQQDEETVRAQ---FIEKGPYAPVPF--------EITEE 3981 Query: 3711 GPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTC 3770 G V R+ G P IDWF +GR + + +D + I +D G+Y C Sbjct: 3982 GDVKLQVRI--CGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKC 4039 Query: 3771 RATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPP 3830 N G AT T D+ +E+ P RG +S E I+ P Sbjct: 4040 IIKNIAGKATRTF--------DVDIEAVKP--------SRHVRGELS----EHLIL---P 4076 Query: 3831 KFI--TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 KFI T++ + V ++ D ++W ++G+++ RY D Sbjct: 4077 KFIDVTEVSPYRVSYDGDFTLTVKLSGSGD----VQWMKDGEVIEDSKRYVIRQDDDLHM 4132 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924 L IL +D G Y C N G D I + L Sbjct: 4133 LTILGATEDDLGTYKCVVTNKAGFDTRSFDIGLEDL 4168 Score = 51.6 bits (118), Expect = 2e-05 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 2/96 (2%) Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635 Q P LK+ E+KEG+ + ++ + +A +K W + +PLK G F + Sbjct: 2031 QPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVK--WLKDGEPLKPGDHFKTERHGDTY 2088 Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671 L I ED G Y C A+N G A T +V S Sbjct: 2089 FLIIPEADVEDEGRYRCEAVNNAGRASTEADILVES 2124 Score = 51.6 bits (118), Expect = 2e-05 Identities = 25/76 (32%), Positives = 40/76 (52%) Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797 A F+ +IT K +P ++WL+ LI F+ +G L + + +D G C AT Sbjct: 2854 AIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATN 2913 Query: 4798 AAGQVETSAKLVVKSK 4813 +AG V + A L+V+ K Sbjct: 2914 SAGTVTSMASLIVRDK 2929 Score = 51.6 bits (118), Expect = 2e-05 Identities = 25/66 (37%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156 T E +VEE PP F+ P ++ + EG+ A+F RV+G P P V WL +G I G R Sbjct: 3048 TAELLVEEGMR--PPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRR 3105 Query: 4157 YKLTYD 4162 +++ ++ Sbjct: 3106 FQIEFE 3111 Score = 51.6 bits (118), Expect = 2e-05 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 6/96 (6%) Query: 1836 VEVAVNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892 VE+ V++A P F+ +++ +L+EG+ A ++ RI P P V WY + ++ G R Sbjct: 3145 VELLVDEAVVPPEFVRKISN-IELTEGEIARFDVRITGTPAPE--VTWYKDEVPIEDGGR 3201 Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928 + +D +L I D+G Y+CKA N GQA Sbjct: 3202 FEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA 3237 Score = 51.6 bits (118), Expect = 2e-05 Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 3/104 (2%) Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468 D E KG P F + +E + EG+ A FE T P +EW+ NG LK R Sbjct: 3342 DIEASEPKGSTPQFIDLMQPVE-VTEGQTATFEC--TVKGYPRPSIEWFKNGLPLKENER 3398 Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 + + L I+ +D G Y C A N++G+A + V Sbjct: 3399 IASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442 Score = 51.6 bits (118), Expect = 2e-05 Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 5/100 (5%) Query: 2639 QQAPIF--TTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696 +Q PIF T +K ++ EG ++ V+ P +EW K+ + + + +K T + Sbjct: 4845 KQEPIFIETDEVKPFEVTEEGD---IKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEE 4901 Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 + +L+I D G+YT K TN +G T +K+ED Sbjct: 4902 DDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVED 4941 Score = 50.8 bits (116), Expect = 3e-05 Identities = 36/112 (32%), Positives = 55/112 (49%), Gaps = 5/112 (4%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F +PL + V EGK L+ ++ + P V+W +G + G FKT Sbjct: 2033 PFFQKPLKDKE-VKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTYF 2089 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE-QAIEQ 1287 L I A D G Y AVN+ G A T A + ++E +D ++ ++E Q +EQ Sbjct: 2090 LIIPEADVEDEGRYRCEAVNNAGRASTEADI-LVESADEGSEPEDEPQQMEQ 2140 Score = 50.8 bits (116), Expect = 3e-05 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 3/87 (3%) Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028 K P+F+ +Q + E +T FEC + G P +EWF NG PL R Y+ Sbjct: 3349 KGSTPQFIDLMQP-VEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENERIASTYEG 3405 Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYG 4055 ++ +D G Y C A N +G Sbjct: 3406 ALSSLTINQCTIDDEGNYKCVARNSFG 3432 Score = 50.4 bits (115), Expect = 3e-05 Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 3/93 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+F R L+D+ + EG + F+ Q+T +P +V WY +G+ + + + + + S Sbjct: 2300 PKFERNLKDI-TIAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHVDIVHDDEHSS 2356 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 L +MH + +G YT A N++G+ S A + + Sbjct: 2357 LILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389 Score = 50.4 bits (115), Expect = 3e-05 Identities = 41/163 (25%), Positives = 67/163 (41%), Gaps = 11/163 (6%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 PP T+++ + + V+F G P PL+KW+ ++ I N I T S L+ Sbjct: 2588 PPKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTSSLV 2647 Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVE----EKRRQGRGGIV-------PPSFTL 4518 + V D+ V+ + N G ++ + V+ E Q V PSFT Sbjct: 2648 LVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKGVKIEPAIQEPVEAVLSLPRGEAPSFTK 2707 Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561 + V VRL+ +VTG V+ N + + IR + Sbjct: 2708 KITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQTKRRCIRER 2750 Score = 50.4 bits (115), Expect = 3e-05 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643 ++ VE+ EGQ A FE + + +EW+ N PLK R T +L I C Sbjct: 3359 MQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSLTINQCT 3416 Query: 1644 PEDSGTYTCRAINALGEA 1661 +D G Y C A N+ G+A Sbjct: 3417 IDDEGNYKCVARNSFGKA 3434 Score = 50.0 bits (114), Expect = 5e-05 Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 6/131 (4%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P+F+ ++ ++ EGQ+A FE V+ ++EW+ NG + RI + ++ + Sbjct: 3353 PQFIDLMQPV-EVTEGQTATFECTVKGYP--RPSIEWFKNGLPLKENERIASTYEGALSS 3409 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID---TSSIHRGLYEKTRHIEE 1159 L I +D G Y VARN+ G+A + + V+ S + + I E R E Sbjct: 3410 LTINQCTIDDEGNYKCVARNSFGKASCATELLVDEADSPEDQVSGKIMNFDRELKRDFEA 3469 Query: 1160 SKFVEPMYQIE 1170 P Q+E Sbjct: 3470 EDLFNPKVQVE 3480 Score = 50.0 bits (114), Expect = 5e-05 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 1/102 (0%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 VEWLKD RPV + S I +LTI+ T D G YT + N +G T + ++ + Sbjct: 4881 VEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVE 4940 Query: 1003 -TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKP 1043 T + + P +E ++ S VKIT KP Sbjct: 4941 DTTTSLFEGTVRPKFIEDDSFVPFESTEEGNVRLSVKITGKP 4982 Score = 49.6 bits (113), Expect = 6e-05 Identities = 26/93 (27%), Positives = 43/93 (46%) Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 +PP F K ++ V E + + +V+ P +KW ++ P+K F+ L Sbjct: 2031 QPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFL 2090 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501 II + VED + A N G A A+++VE Sbjct: 2091 IIPEADVEDEGRYRCEAVNNAGRASTEADILVE 2123 Score = 49.6 bits (113), Expect = 6e-05 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 3/90 (3%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 EE + P F V S+++ + EG+ A FEAR++ P +VEW +G+ +K G RF+ Sbjct: 3054 EEGMRPPQFIVKPSSLQ-IMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEF 3110 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGE 3503 + +L I D GEY C A + G+ Sbjct: 3111 EKDRSVLTIIDAKLNDEGEYTCVATSKAGK 3140 Score = 49.6 bits (113), Expect = 6e-05 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 2/99 (2%) Query: 631 DRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR 690 D PP+F+ + ++ EG F+ RI G P ++ W K+ IE RF Sbjct: 3150 DEAVVPPEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYSD 3207 Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729 SL + + D+G Y+C+A + G A L +T Sbjct: 3208 DDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTIT 3246 Score = 49.6 bits (113), Expect = 6e-05 Identities = 72/305 (23%), Positives = 118/305 (38%), Gaps = 36/305 (11%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130 TG + WF +G + + I + +L I +GTY C ATN+ G Sbjct: 3878 TGFPEPDVSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLYAGTYKCVATNRRGTNSR 3937 Query: 3131 QAEISVKL-ECVDKSKGQKPRFTTHIQNIE-------GLKDGQSAHFECTVVPVDDPDMK 3182 E++++ E + Q+ T Q IE + + + V P + Sbjct: 3938 DFEVTIETGEAAEHITFQQDEETVRAQFIEKGPYAPVPFEITEEGDVKLQVRICGIPFPE 3997 Query: 3183 IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242 I+W+ +G+ + IK SD + I D+G+Y C N G+ TR Sbjct: 3998 IDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGK-ATRTF---- 4052 Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302 V +E+++P + E L PKFI + +V+ F Sbjct: 4053 ---DVDIEAVKPSRHVRGELSEHL-------------ILPKFI-DVTEVSPYRVSYDGDF 4095 Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362 + D V+W +G+ + RY D + +L IL E++ G Y+CV TNK Sbjct: 4096 TLTVKLSGSGD--VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNK 4153 Query: 3363 LGRDS 3367 G D+ Sbjct: 4154 AGFDT 4158 Score = 49.6 bits (113), Expect = 6e-05 Identities = 83/404 (20%), Positives = 158/404 (39%), Gaps = 40/404 (9%) Query: 4040 PEDSGEYLCRATNLYGMD------ETKAVIKTTGKPGI-----VYDSQLPKHMKSIEKIR 4088 P D+G Y C ++ YG E + + +P ++ L + S+ KI Sbjct: 4762 PNDTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEETMSVTKIL 4821 Query: 4089 EMEASWQ-VTPEQ-VVEE--SKARCPPVFVSLPDAV---TVEEGEWARFCCRVTGHPKPR 4141 + E + + PE+ ++E+ SK + P+F+ + EEG+ + +VTG PKP Sbjct: 4822 QDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGD-IKMTVKVTGKPKPS 4880 Query: 4142 VMWLLNGNTIVNGSRYKLT-YDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVI 4200 V WL + +++ S K+T D +Y I + + D G V +KV Sbjct: 4881 VEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKV- 4939 Query: 4201 PRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKE 4260 D + + RP + E + E T E L + PE+ ++ Sbjct: 4940 --EDTTTSLFEGTVRPKFIEDDSF----VPFESTEEGNVRLSVKITGKPVPEVSWTKDEK 4993 Query: 4261 PETEWQQSVKRKKNEEYYNKLQE-LENEQVIKESRLR----ESTHQYAIPGDKVTSNTVA 4315 P + Q +++ Y ++E N+ + L +ST +++ ++ T Sbjct: 4994 PVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSV---EIEGETKP 5050 Query: 4316 KSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGD 4375 + + EE + +V KP + + + +EV K K T++E Sbjct: 5051 EKGKPTEREGKPLEEEELPVSAETEVEVKPLVETITRKEIKVEEVKPKKGKPTEREA--- 5107 Query: 4376 KEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQP 4419 K K E I + +E+ +E P+ + + +K++P Sbjct: 5108 KPFEEKPLIEEELPISAEKVVEEKPLEKPIARKEKKV--EKVKP 5149 Score = 49.2 bits (112), Expect = 8e-05 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 2/113 (1%) Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367 +Q P F + L + E EG L+ ++ + + V+W +G+P+K G F+ D Sbjct: 2030 IQPPFFQKPLKDKEVKEGKPFKLDVKITALPEAN--VKWLKDGEPLKPGDHFKTERHGDT 2087 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK 1420 L + ED G Y C+A N G A T + V + + P +E+ Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQ 2140 Score = 49.2 bits (112), Expect = 8e-05 Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 8/144 (5%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYV- 1768 P F ++DI V E R+ G PK V+W ++G P+ +R + G V Sbjct: 2200 PEFKSALRDIEVNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828 L +K D+G Y C+A N GE +S + V A + + E L+ I E S Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKE-PPKFERNLKDITIAEGCS 2316 Query: 1829 RYQRREDVEVAVNQAPRFITQLNG 1852 R DV+V + P+ NG Sbjct: 2317 ---TRFDVQVTGSPEPKVFWYHNG 2337 Score = 49.2 bits (112), Expect = 8e-05 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 11/132 (8%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 + E +P+F + + +SI G E R+ G +V W KD + + SR + Sbjct: 2389 ITELAIQPKFAERLTN-VSISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFE 2445 Query: 962 FNFGYVA-LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK-------KDIIAESQH 1013 G V LTI+ VT D G Y C A N GQ T A LT+ + K+++ Sbjct: 2446 TRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGNPPFFVKELVDIDVT 2505 Query: 1014 PGGLEKIQYLED 1025 GG E+ + + D Sbjct: 2506 EGGHERFEVVVD 2517 Score = 49.2 bits (112), Expect = 8e-05 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894 ++ VA P F + ++EG +E ++ YP P ++WY N +++ G ++ Sbjct: 2483 ELTVAKRGNPPFFVKELVDIDVTEGGHERFEVVVDGYPKPE--IDWYKNDILIRPGPKFD 2540 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 L + E++G+ TCKA N+ GQA+ S + + K Sbjct: 2541 IKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585 Score = 49.2 bits (112), Expect = 8e-05 Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 2/95 (2%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637 P L ++++ EG FE ++ +++WY N+ ++ G +F + L Sbjct: 2493 PFFVKELVDIDVTEGGHERFE--VVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTL 2550 Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672 + C PE++G TC+A N+ G+A+ S ++ K Sbjct: 2551 IVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585 Score = 49.2 bits (112), Expect = 8e-05 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F + DI V E FE ++ G PK ++W +N + I + + L Sbjct: 2493 PFFVKELVDIDVTEGGHERFE--VVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTL 2550 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 +K PE++G TC+A N G+A+ S + + K Sbjct: 2551 IVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585 Score = 49.2 bits (112), Expect = 8e-05 Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 9/149 (6%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F + +++ E + A FEAR+ + P+ VEWLR+G PI+ R + L Sbjct: 3060 PQFIVKPSSLQIMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEFEKDRSVL 3117 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830 + D G YTC A ++ G+ S L V +A + E ++KI +E + Sbjct: 3118 TIIDAKLNDEGEYTCVATSKAGKDSCSVELLV-DEAVVPPE-----FVRKISNIELTEGE 3171 Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEG 1859 R DV + AP +T + +G Sbjct: 3172 IARFDVRITGTPAPE-VTWYKDEVPIEDG 3199 Score = 48.8 bits (111), Expect = 1e-04 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 6/128 (4%) Query: 3800 PQGMSGEK--IKELERGRISDAPKEEPI-VSTPPKFITQIKSHTVEESEGVRFECRVEPK 3856 P +SG+ + E E G++ A + ++ PKF ++ + ++ + + ECRV K Sbjct: 2363 PLDLSGKYTCVAENEVGQVQSAARLHITELAIQPKFAERLTNVSISSGDTIVLECRVTGK 2422 Query: 3857 EDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS-LDILYVYAEDSGEYICRAVNDFGEDFT 3915 P+ ++ W+++ K + R+ G V L I V +D G Y C A N G+D T Sbjct: 2423 --PRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDT 2480 Query: 3916 KATISCKK 3923 A ++ K Sbjct: 2481 VAELTVAK 2488 Score = 48.8 bits (111), Expect = 1e-04 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 6/98 (6%) Query: 1435 IIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494 ++DE+V + P FV + +IE + EG+ F+ ++ +V W+K+ P+ G RF Sbjct: 3148 LVDEAV-VPPEFVRKISNIE-LTEGEIARFDVRITGTPAP--EVTWYKDEVPIEDGGRFE 3203 Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532 D +L I D D+G Y+C+A N G + SC Sbjct: 3204 IYSDDDKHSLVIRDCALSDTGSYSCKATNEAG--QASC 3239 Score = 48.8 bits (111), Expect = 1e-04 Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 4/111 (3%) Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227 + E S P F+ L P V+EG+ EC ++ G P +EWF NG + R Sbjct: 3344 EASEPKGSTPQFID-LMQPVEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENERIA 3400 Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTD 1278 + Y+ +L I T D G Y A N G A + A +++ +D D Sbjct: 3401 STYEGALSSLTINQCTIDDEGNYKCVARNSFGKA-SCATELLVDEADSPED 3450 Score = 48.4 bits (110), Expect = 1e-04 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501 I+P F +P + V EG+ + K+ + ++N+K W K+G+P+ G F+ Sbjct: 2030 IQPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVK--WLKDGEPLKPGDHFKTERHGDT 2087 Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVG 1526 L I + ED G Y C AVN G Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAG 2112 Score = 48.4 bits (110), Expect = 1e-04 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 3/96 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P F L D + EG H E V+ P +I+W+KN + + G + T Sbjct: 2493 PFFVKELVDID-VTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEHGDHHT 2549 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 L + R +++G TCKA N G+A+ + ++I ++ Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585 Score = 48.0 bits (109), Expect = 2e-04 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578 EL EG+ A ++ R+ G P+ WY + V ++ G RF D +L I +D Sbjct: 3166 ELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDT 3223 Query: 2579 GLYMCKAINRAG 2590 G Y CKA N AG Sbjct: 3224 GSYSCKATNEAG 3235 Score = 48.0 bits (109), Expect = 2e-04 Identities = 30/80 (37%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Query: 922 KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981 +EGG FEA + G VEW KD P+ SS + +LTI+ V D+G Sbjct: 3266 EEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGA 3323 Query: 982 YTCRAYNAIGQATTSANLTI 1001 YTC A N G A + N+ I Sbjct: 3324 YTCTATNECGMAKRTYNIDI 3343 Score = 48.0 bits (109), Expect = 2e-04 Identities = 83/399 (20%), Positives = 141/399 (35%), Gaps = 55/399 (13%) Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539 L I P D+G Y C ++YG + T ++++ + PK +E +K + E Sbjct: 4755 LTIREPSPNDTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYPK-VEPFHEKPLSEE 4813 Query: 3540 GYSGT--------VDTLTPE--------AESGNPPEFTTTPSDLILSENSSAHFECRLIP 3583 S T ++ PE ++ P F T + + Sbjct: 4814 TMSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKV 4873 Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643 VEW + +P+L+ S +K + L I + D G+YT K TN G T Sbjct: 4874 TGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTR 4933 Query: 3644 SCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKD 3703 + ++V+ + E + F IED+ P T E Sbjct: 4934 TFDVKVEDTTTSLFEGTVRPKF---------------------IEDDSFVPFESTEE--- 4969 Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763 G V ++ G P + W + +P + + L I Sbjct: 4970 -------GNVRLSVKI--TGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPN 5020 Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE- 3822 D+G Y C TN G +T T + + + E P G+ ++E E ++ E Sbjct: 5021 DSGSYKCTLTNDAGKSTRTFSV--EIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEV 5078 Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861 +P+V T + +IK V+ +G E +P E+ L Sbjct: 5079 KPLVETITR--KEIKVEEVKPKKGKPTEREAKPFEEKPL 5115 Score = 47.6 bits (108), Expect = 2e-04 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 2/95 (2%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P F + L +I+ EG + E + G ++W+ N I+ G +F D+ L Sbjct: 2493 PFFVKELVDIDVTEGGHERFEVVVD--GYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTL 2550 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 + PE++G TC+A N G+A+ SC +++ K Sbjct: 2551 IVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585 Score = 47.6 bits (108), Expect = 2e-04 Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 7/126 (5%) Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 PP+F+ +I + + E E RF+ R+ P+ + WY++ + G R+ D S Sbjct: 3155 PPEFVRKISNIELTEGEIARFDVRITGTPAPE--VTWYKDEVPIEDGGRFEIYSDDDKHS 3212 Query: 3889 LDILYVYAEDSGEYICRAVNDFGED--FTKATISCKKLPDIILQN--QVPRGMKRSEALT 3944 L I D+G Y C+A N+ G+ + + TI+ +P + ++P + +T Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQASCYGELTITFIPVPPHFTEEAPKIPTDFEEGGDIT 3272 Query: 3945 QMEATI 3950 EAT+ Sbjct: 3273 -FEATV 3277 Score = 47.6 bits (108), Expect = 2e-04 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G+ P+F + ++E +A FEC + S +EWF NG PL R+ + + Sbjct: 3350 GSTPQFIDLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGAL 3407 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 L I D G Y C A N G+A+ + +L V Sbjct: 3408 SSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442 Score = 47.6 bits (108), Expect = 2e-04 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 82 RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDE 141 + + G+ K ++ G P P V+WT+ P+ E + + + T +L+IK DE Sbjct: 4511 QLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDT--YTLIIKSPTDKDE 4568 Query: 142 GEYTCTARNQYG 153 G Y CTA N G Sbjct: 4569 GIYKCTASNSVG 4580 Score = 47.2 bits (107), Expect = 3e-04 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 3/111 (2%) Query: 1831 QRREDVEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889 ++R E+ + P F + ++ EG+ + +I P+ N V+W +G+ L+ Sbjct: 2018 KKRSTAEIMMGDIQPPFFQKPLKDKEVKEGKPFKLDVKITALPEAN--VKWLKDGEPLKP 2075 Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 G ++T L I ED G Y C+A+NN G+A + + V+S + Sbjct: 2076 GDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESAD 2126 Score = 47.2 bits (107), Expect = 3e-04 Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 3/112 (2%) Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339 +PP F ++D ++ EG+ + ++ + P+ V+W +G+ L G ++T Sbjct: 2031 QPPFFQKPLKD-KEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087 Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGME 3391 L I E+ G Y C A N GR ST+A++ S + P+ ME Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQME 2139 Score = 47.2 bits (107), Expect = 3e-04 Identities = 29/92 (31%), Positives = 37/92 (40%), Gaps = 3/92 (3%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753 PP F +KD +V EG P D ++ + P + W +G P G T Sbjct: 2032 PPFFQKPLKDK-EVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTY 2088 Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 L I D G Y C A N G A+T A I Sbjct: 2089 FLIIPEADVEDEGRYRCEAVNNAGRASTEADI 2120 Score = 47.2 bits (107), Expect = 3e-04 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P+F + +K+ + EG + +T P +V WY NG+ VQ +D + Sbjct: 2298 EPPKFERNLKDITIAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDDEHS 2355 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 +L +++ + +G Y C A N VG+ + + + + Sbjct: 2356 SLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389 Score = 47.2 bits (107), Expect = 3e-04 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 4/99 (4%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 +P+F + + N ++ G + LE +T P +V W+ + + ++Q RF G V Sbjct: 2395 QPKFAERLTNVSISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVC 2452 Query: 2037 -LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074 L I +D G+Y C ATN G+ T + + V AK G Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTV-AKRG 2490 Score = 47.2 bits (107), Expect = 3e-04 Identities = 39/129 (30%), Positives = 55/129 (42%), Gaps = 7/129 (5%) Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228 +EE + V+P S + EGK E R+ G P VEW +GR + G RF+ Sbjct: 3053 VEEGMRPPQFIVKPSSLQ--IMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRRFQI 3108 Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQI 1288 ++ L II A D GEYT A + G S + V + V + + I I Sbjct: 3109 EFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLV---DEAVVPPEFVRKISNI 3165 Query: 1289 QLLEDAARR 1297 +L E R Sbjct: 3166 ELTEGEIAR 3174 Score = 47.2 bits (107), Expect = 3e-04 Identities = 25/88 (28%), Positives = 41/88 (46%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P+ VEW ++ PI S+ +L ++ V P+DSG YTC A NE G A + Sbjct: 3279 GRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRT 3338 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLE 1825 + +++ Q +Q ++ E Sbjct: 3339 YNIDIEASEPKGSTPQFIDLMQPVEVTE 3366 Score = 46.8 bits (106), Expect = 4e-04 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100 + P+F LK I EG S F+ +V + V WY NGK + + + HD + Sbjct: 2298 EPPKFERNLKDIT-IAEGCSTRFDVQVTGSPE--PKVFWYHNGKLVQPRDHVDIVHDDEH 2354 Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 +L + + SG YT VA N G+ Q +A + + Sbjct: 2355 SSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389 Score = 46.8 bits (106), Expect = 4e-04 Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 2/94 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 + P+F R L +I EG + + +Q G +V W+ NGK ++ ++ ++ Sbjct: 2298 EPPKFERNLKDITIAEGCSTRFD--VQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHS 2355 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 +L L+ + SG YTC A N++G+ ++ L + Sbjct: 2356 SLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389 Score = 46.8 bits (106), Expect = 4e-04 Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 5/99 (5%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P+F ++ + S+ +T EC++ G P +V WF + K + +RF+ G V Sbjct: 2396 PKFAERL-TNVSISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVC 2452 Query: 4033 -MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPG 4070 + V P+D G Y C ATN G D+T A + T K G Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAEL-TVAKRG 2490 Score = 46.8 bits (106), Expect = 4e-04 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 4/107 (3%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 E+T+ ++ NPP F E+ D IDV EGG F+ V+ G P IDW+ N G + Sbjct: 2483 ELTVA-KRGNPPFFVKELVD-IDVTEGGHERFEVVVD--GYPKPEIDWYKNDILIRPGPK 2538 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 L + + G+ TC+A N G A + + + K Sbjct: 2539 FDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585 Score = 46.8 bits (106), Expect = 4e-04 Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 5/89 (5%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P+F+ + +E V EGQ FEC ++ + +EWFKNG P+ R ++ + Sbjct: 3353 PQFIDLMQPVE-VTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSS 3409 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532 L I +D G Y C A N G + SC Sbjct: 3410 LTINQCTIDDEGNYKCVARNSFG--KASC 3436 Score = 46.4 bits (105), Expect = 6e-04 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 2/91 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F +L +I EG + F+ V S +P K+ W+ N K + HD + SL + Sbjct: 2302 FERNLKDITIAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHVDIVHDDEHSSLIL 2359 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866 H + SG YTC A N G ++ L T Sbjct: 2360 MHCPLDLSGKYTCVAENEVGQVQSAARLHIT 2390 Score = 46.4 bits (105), Expect = 6e-04 Identities = 48/178 (26%), Positives = 74/178 (41%), Gaps = 16/178 (8%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 +P F + L+N +S G I LECR+ G P +V WF + + + SRF G V Sbjct: 2395 QPKFAERLTNVS-ISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDV 2451 Query: 1236 -ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER-------SDIVTDTQNEQAIEQ 1287 L I T D G Y A N G T A + V +R ++V E E+ Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGNPPFFVKELVDIDVTEGGHER 2511 Query: 1288 IQLLEDAARRTK--QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMR 1343 +++ D + + + DI + P+F H T + +CR + G T + Sbjct: 2512 FEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHG---DHHTLIVKDCRPEETGKLTCK 2566 Score = 46.4 bits (105), Expect = 6e-04 Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 G P F+ L ++ + EG FE V+ P IDW+ N IR G ++ Sbjct: 2490 GNPPFFVKELVDID-VTEGGHERFEVVVDGYPKPE--IDWYKNDILIRPGPKFDIKEHGD 2546 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + L + E++G CKA N G+A+ +C +++ Sbjct: 2547 HHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQI 2582 Score = 46.4 bits (105), Expect = 6e-04 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 4/107 (3%) Query: 3951 KKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWF 4010 K EV T + L + + +PP+F+ + S ++E + KFE +++ G P +VEW Sbjct: 3039 KNKVGEVSCTAELLVE-EGMRPPQFIVK-PSSLQIMEGKMAKFEARVS--GLPGPEVEWL 3094 Query: 4011 FNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057 +G+P+ RF ++ + D GEY C AT+ G D Sbjct: 3095 RDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKD 3141 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/85 (30%), Positives = 47/85 (55%), Gaps = 3/85 (3%) Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970 PE++ I+ +L EG++ + ++ P+ + WY + +E G RF++ SD + Sbjct: 3156 PEFVRKIS-NIELTEGEIARFDVRITGTPAPE--VTWYKDEVPIEDGGRFEIYSDDDKHS 3212 Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEA 2995 L + D D+G Y+CKA N+ G+A Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQA 3237 Score = 46.4 bits (105), Expect = 6e-04 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 2/88 (2%) Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912 PT EG +E + P P+ VEW+ + + Y +L I V + Sbjct: 3262 PTDFEEGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPD 3319 Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 DSG YTC A N G A + +++++ E Sbjct: 3320 DSGAYTCTATNECGMAKRTYNIDIEASE 3347 Score = 46.4 bits (105), Expect = 6e-04 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 2/84 (2%) Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840 + +EG + FEA ++ P VEW+KD PI+ SS + SL I + +D+ Sbjct: 3264 DFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDS 3321 Query: 841 GSYTVRAVNKLGEAISTASIRVAA 864 G+YT A N+ G A T +I + A Sbjct: 3322 GAYTCTATNECGMAKRTYNIDIEA 3345 Score = 46.4 bits (105), Expect = 6e-04 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 2/80 (2%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 EG + EA V R P+ +EW K+ ++ + +L+I + DDSG Y Sbjct: 3267 EGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAY 3324 Query: 2716 TCKATNLLGEAVSTASIKIE 2735 TC ATN G A T +I IE Sbjct: 3325 TCTATNECGMAKRTYNIDIE 3344 Score = 46.4 bits (105), Expect = 6e-04 Identities = 38/132 (28%), Positives = 57/132 (43%), Gaps = 10/132 (7%) Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843 V +EGD + V+ + P +EW +++P+ S + K T + SL I + D Sbjct: 4861 VTEEGD---IKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDE 4917 Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFD-TQHPQ--GKAGLEAVEQAEEARLAKGRR 2900 G+YT K TN GS T + ++ F+ T P+ E EE + R Sbjct: 4918 GMYTVKITNDVGSGTRTFDVKVEDTTTSLFEGTVRPKFIEDDSFVPFESTEEGNV----R 4973 Query: 2901 PSVPDTEYPKPE 2912 SV T P PE Sbjct: 4974 LSVKITGKPVPE 4985 Score = 46.0 bits (104), Expect = 8e-04 Identities = 51/185 (27%), Positives = 81/185 (43%), Gaps = 16/185 (8%) Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAG---EYSVKAINALGHCTSAISMTVTAKGS 2339 +A+ +A R D S D + PED E S K I A+G A+++T+ K Sbjct: 2106 EAVNNAGRASTEADILVESAD-EGSEPEDEPQQMEQSTKTI-AIGQEPPAVTLTLDGKAG 2163 Query: 2340 I---ISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHF 2396 E + P E E + + +P+P+ P F L++I+ + EG T Sbjct: 2164 FDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIP---PEFKSALRDIE-VNEGNTVTL 2219 Query: 2397 DCRLIPVGDPTLKVEWFRNEKLIED-SSRITKTHDFGYV-SMTISHVRDEDEGVYMCRAS 2454 R+ G P +V+WF++ K + R + G V ++ I R D G Y+C+A Sbjct: 2220 --RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAY 2277 Query: 2455 NLLGE 2459 N GE Sbjct: 2278 NSAGE 2282 Score = 46.0 bits (104), Expect = 8e-04 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 3/104 (2%) Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022 D+ V K+PP+F ++ T + E +T+F+ Q+ G P KV W+ NGK + ++ Sbjct: 2290 DVLHVAPKEPPKFERNLKDIT-IAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHV 2346 Query: 4023 TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066 ++D + ++ + SG+Y C A N G ++ A + T Sbjct: 2347 DIVHDDEHSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHIT 2390 Score = 46.0 bits (104), Expect = 8e-04 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 2/96 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P F K + + +VTEG E + P ++WY N ++ G +F + L Sbjct: 2493 PFFVKELVDIDVTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEHGDHHTL 2550 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 + E+TG CKA N+ G+A+ + V+++ K+ Sbjct: 2551 IVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKT 2586 Score = 46.0 bits (104), Expect = 8e-04 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 9/125 (7%) Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295 E + PP+F+ + + + EGK A FE +V + P +E+ +G+ ++ RF I F Sbjct: 3054 EEGMRPPQFIVK-PSSLQIMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEF 3110 Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRE 2355 + L I D GEY+ A + G + ++ + V +++ PE + KI Sbjct: 3111 EKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDE--AVVP----PEFVRKISN 3164 Query: 2356 LESAE 2360 +E E Sbjct: 3165 IELTE 3169 Score = 46.0 bits (104), Expect = 8e-04 Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 15/132 (11%) Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845 +EG +I FE V S P +EW + P+ + Y SL I +DSG Sbjct: 3266 EEGGDITFEATV--SGRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGA 3323 Query: 2846 YTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPD 2905 YTC ATN G A + NI + P+G + ++ + + +G+ + Sbjct: 3324 YTCTATNECGMAKRT--------YNIDIEASEPKGSTP-QFIDLMQPVEVTEGQTATFEC 3374 Query: 2906 T--EYPKP--EW 2913 T YP+P EW Sbjct: 3375 TVKGYPRPSIEW 3386 Score = 46.0 bits (104), Expect = 8e-04 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 4/99 (4%) Query: 57 DRQPIT-AGRPGEPSPPIFEQIFKNA-RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE 114 D +P T A P E P + + A + G+ K ++RG P P V WT+ P+V Sbjct: 4167 DLRPHTFAYEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRVRGKPKPTVKWTKNDEPVVP 4226 Query: 115 CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 + +S+ + SLLI++ D+G Y A N+ G Sbjct: 4227 SSHFSVLMEDDV--FSLLIRKPSKTDKGVYKVIATNEGG 4263 Score = 45.6 bits (103), Expect = 0.001 Identities = 59/245 (24%), Positives = 100/245 (40%), Gaps = 41/245 (16%) Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852 F+ +V+ + P ++W + +PL G +K+ L I ED G Y C+A N Sbjct: 2050 FKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVN 2109 Query: 2853 SKG-SATTSGSLRCTGD----------------KNIYFDTQHP------QGKAGLE--AV 2887 + G ++T + L + D K I + P GKAG + AV Sbjct: 2110 NAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAIGQEPPAVTLTLDGKAGFDFQAV 2169 Query: 2888 E---------QAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPK 2938 E E+ R+ + ++P P P + ++ EG + L ++ Sbjct: 2170 ELKIPHPDEIAEEDLRIDVEQTAALPK---PIPPEFKSALRDIEVNEGNTVTL--RIHVT 2224 Query: 2939 NDPDLKIEWYFNGKVLE--QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAF 2996 P +++W+ +GK + RF++ TL + + D+G Y CKAYN GE Sbjct: 2225 GSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVT 2284 Query: 2997 TSSTV 3001 +S V Sbjct: 2285 SSCNV 2289 Score = 45.6 bits (103), Expect = 0.001 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS- 695 P+F L +V+ G I E R+ G P ++ W K+ + I SRF+ R G + Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCV 2453 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 L + + D G Y C A + G +T A L V R Sbjct: 2454 LTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKR 2489 Score = 45.2 bits (102), Expect = 0.001 Identities = 39/150 (26%), Positives = 71/150 (47%), Gaps = 16/150 (10%) Query: 3231 GEDFTRATINCYGKGGVYLESLQ-----PDSLAKIRELESLQGAQQQTPSTPSAEPPKFI 3285 G++ T+ GK G ++++ PD +A+ E L+ +QT + P PP+F Sbjct: 2148 GQEPPAVTLTLDGKAGFDFQAVELKIPHPDEIAE----EDLRIDVEQTAALPKPIPPEFK 2203 Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKK---LPHGHRYRTFHDFGIVIL 3342 + ++D+ ++ EG + R+ P +V+WF +GK LPH R+ + L Sbjct: 2204 SALRDI-EVNEGNTV--TLRIHVTGSPKPEVDWFKDGKPVSGLPH-RRFEVGCVGEVYTL 2259 Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANL 3372 I ++G+Y C A N G ++ N+ Sbjct: 2260 VIKEARGSDTGKYLCKAYNSAGEVTSSCNV 2289 Score = 45.2 bits (102), Expect = 0.001 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 4/100 (4%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR-TTHDFGY 2166 +P F LT++ ++ GD ECRV P + WF + ++IR R+ T Sbjct: 2395 QPKFAERLTNV-SISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDV 2451 Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRN 2206 L I +D G+Y C ATN G+ L VA N Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491 Score = 45.2 bits (102), Expect = 0.001 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 4/99 (4%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV- 3478 P F L+N+ ++ G+ E R+T P +V W+ + K ++ SRF G V Sbjct: 2396 PKFAERLTNV-SISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVC 2452 Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517 +L I P+D G Y C A N G+ T A + V + N Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491 Score = 45.2 bits (102), Expect = 0.001 Identities = 28/106 (26%), Positives = 54/106 (50%), Gaps = 4/106 (3%) Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690 E+ V+ G++ P F S +++EG+ EA+V P ++EW ++G + G R Sbjct: 3050 ELLVEEGMRP-PQFIVKPSSL-QIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRR 3105 Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 + F+ L+I + +D G YTC AT+ G+ + + +++ Sbjct: 3106 FQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDE 3151 Score = 45.2 bits (102), Expect = 0.001 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113 +I+EG+ A FEARV VEW +G+ I R Q + L I + D Sbjct: 3070 QIMEGKMAKFEARVSGLPG--PEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDE 3127 Query: 1114 GVYTVVARNAAGEAQLSASMTVE 1136 G YT VA + AG+ S + V+ Sbjct: 3128 GEYTCVATSKAGKDSCSVELLVD 3150 Score = 45.2 bits (102), Expect = 0.001 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158 E +V+E A PP FV + + EGE ARF R+TG P P V W + I +G R++ Sbjct: 3146 ELLVDE--AVVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFE 3203 Query: 4159 LTYDGMYH 4166 + D H Sbjct: 3204 IYSDDDKH 3211 Score = 44.8 bits (101), Expect = 0.002 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%) Query: 3276 TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH 3335 T A PKF ++ +V+ + G + E R+ P +V WF + K++ R+ Sbjct: 2390 TELAIQPKFAERLTNVS-ISSGDTIVLECRVTGKPRP--QVAWFKDDKEIRQDSRFSFET 2446 Query: 3336 DFG-IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379 G + +L I ++ G Y+C+ATN G+D T A L + N Sbjct: 2447 RPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491 Score = 44.8 bits (101), Expect = 0.002 Identities = 59/253 (23%), Positives = 103/253 (40%), Gaps = 36/253 (14%) Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028 LTI+ + +D G Y C + G++T + N+ I + A+ +P K++ + Sbjct: 4755 LTIREPSPNDTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYP----KVEPFHEKP- 4809 Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEG-------QSAHFEA-RVEP-----QSDLTM 1075 S+ T KI Q + L P + I+E + E V+P + D+ M Sbjct: 4810 LSEETMSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKM 4869 Query: 1076 TV----------EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAG 1125 TV EW + + + S + I+ + +L I D G+YTV N G Sbjct: 4870 TVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG 4929 Query: 1126 EAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEE--ISKSKPVFVQPL 1183 S + T + + T+S+ G + + IE+ FV P EE + S + +P+ Sbjct: 4930 ----SGTRTFDVKVEDTTTSLFEGTV-RPKFIEDDSFV-PFESTEEGNVRLSVKITGKPV 4983 Query: 1184 SNPPPVSEGKNIH 1196 + K +H Sbjct: 4984 PEVSWTKDEKPVH 4996 Score = 44.4 bits (100), Expect = 0.002 Identities = 56/228 (24%), Positives = 91/228 (39%), Gaps = 41/228 (17%) Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493 D++ + P+F K I + EG F+ ++ + KV W+ NG+ V Sbjct: 2290 DVLHVAPKEPPKFERNLKDI-TIAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHV 2346 Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLE 1553 +HD + +L ++ + SG YTC A +NE G Sbjct: 2347 DIVHDDEHSSLILMHCPLDLSGKYTCVA-------------------------ENEVG-- 2379 Query: 1554 QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEW 1613 Q+Q ++ H T++ + P L NV I G E R+ +V W Sbjct: 2380 QVQ---SAARLHITELAIQ-----PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAW 2429 Query: 1614 YHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 + ++K ++ SRF+ ET L I P+D G+Y C A N G+ Sbjct: 2430 FKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQ 2477 Score = 44.4 bits (100), Expect = 0.002 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 3/85 (3%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P FV+ +SN ++EG+ + R+ G P V W+ + + G RF+ Y D + Sbjct: 3156 PEFVRKISNIE-LTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHS 3212 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSA 1261 L I +DTG Y+ +A N G A Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQA 3237 Score = 44.4 bits (100), Expect = 0.002 Identities = 38/171 (22%), Positives = 62/171 (36%), Gaps = 7/171 (4%) Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133 G + W + K I + I+ L I D G Y C A+N G + Sbjct: 4526 GKPKPTVTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGIYKCTASNSVGTSSQM 4585 Query: 3134 ISVKLECVD---KSKGQK-PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189 V ++ D KSK P F ++E + TV+ P +++W + Sbjct: 4586 FDVDIKGTDWMLKSKDDDFPSFVDE-DDVEAFEMTDEGSIRMTVIVRGKPKPEVKWSKDD 4644 Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240 +P+ ++ I L I + D G Y C A N+ G + +N Sbjct: 4645 KPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVNRAGTNIRSFVVN 4695 Score = 44.0 bits (99), Expect = 0.003 Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 5/150 (3%) Query: 1123 AAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQP 1182 A G+ + ++T++ ++ D ++ + EE ++ + Q + K P + Sbjct: 2146 AIGQEPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRID-VEQTAALPKPIPPEFKS 2204 Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT--VGSRFKTYYDFGFVALDII 1240 V+EG + L R+ G P V+WF +G+ V+ RF+ L I Sbjct: 2205 ALRDIEVNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIK 2262 Query: 1241 HATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270 A +DTG+Y +A N G +S V V+ Sbjct: 2263 EARGSDTGKYLCKAYNSAGEVTSSCNVDVL 2292 Score = 44.0 bits (99), Expect = 0.003 Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 3/89 (3%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLD 2834 F L N+ GD I EC V + P ++ WF ++K + +R+ T L Sbjct: 2398 FAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLT 2455 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 I +D G Y C ATN G T L Sbjct: 2456 IRGVTPDDEGSYKCIATNPAGQDDTVAEL 2484 Score = 43.6 bits (98), Expect = 0.004 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 4/90 (4%) Query: 67 GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126 G+ PP F++ K+ +G K + K+ P V W + PL + + E+ Sbjct: 2028 GDIQPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFK---TERH 2084 Query: 127 GDV-SLLIKQIGPGDEGEYTCTARNQYGEA 155 GD L+I + DEG Y C A N G A Sbjct: 2085 GDTYFLIIPEADVEDEGRYRCEAVNNAGRA 2114 Score = 43.2 bits (97), Expect = 0.005 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 3/118 (2%) Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319 +G + PP + ++ +++EG + V+++ P V W K+G+ L H H Sbjct: 2027 MGDIQPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPL-KPGDHFKTERHG 2085 Query: 320 HT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-SYVQDQRSQYITDTQ 375 T L + D G Y A N G T + VES E S +D+ Q T+ Sbjct: 2086 DTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTK 2143 Score = 43.2 bits (97), Expect = 0.005 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 3/97 (3%) Query: 2105 PGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF 2164 P + P F L + + EG F+ +V P + W+HNG+ ++ HD Sbjct: 2296 PKEPPKFERNLKDI-TIAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDD 2352 Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + +L +++ + SG Y C A N++G+ + L + Sbjct: 2353 EHSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389 Score = 43.2 bits (97), Expect = 0.005 Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 3/95 (3%) Query: 907 QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966 + P+F+ +KD I+I EG F+ ++ G +V W +G+ V+ + + + Sbjct: 2298 EPPKFERNLKD-ITIAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDDEH 2354 Query: 967 VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 +L + + +G YTC A N +GQ ++A L I Sbjct: 2355 SSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389 Score = 43.2 bits (97), Expect = 0.005 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P+F + N+ + G + +CRV G P ++ WF + + SR G + Sbjct: 2396 PKFAERLT-NVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVC 2452 Query: 3755 -LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791 L I + D G Y C ATN G T A++T AKR Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTV-AKR 2489 Score = 43.2 bits (97), Expect = 0.005 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 4/96 (4%) Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690 E+ VD V P F + + + L EG+ + ++ P ++ W+K+ V + G R Sbjct: 3146 ELLVDEAVVP-PEFVRKISNIE-LTEGEIARFDVRITGTPAP--EVTWYKDEVPIEDGGR 3201 Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726 + D +L I D+G Y+CKATN G+A Sbjct: 3202 FEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA 3237 Score = 43.2 bits (97), Expect = 0.005 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 4/86 (4%) Query: 1311 PQFSRALHNIET--VEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 P F+ I T EG ++ E + G VEW + PI + D Sbjct: 3252 PHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDTY 3309 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEA 1394 +L + V P+DSG YTC ATN+ G A Sbjct: 3310 SLTIRGVGPDDSGAYTCTATNECGMA 3335 Score = 43.2 bits (97), Expect = 0.005 Identities = 23/64 (35%), Positives = 33/64 (51%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P +I+WFK+G L+ +K T D L T+ I D+G Y C N+ G+A T Sbjct: 3994 PFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGKATRTFD 4053 Query: 2732 IKIE 2735 + IE Sbjct: 4054 VDIE 4057 Score = 43.2 bits (97), Expect = 0.005 Identities = 67/331 (20%), Positives = 122/331 (36%), Gaps = 41/331 (12%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKLE 3139 I+WF +G+ + I+ + + I D+G Y C N G+A V +E Sbjct: 3998 IDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGKATRTFDVDIE 4057 Query: 3140 CVDKSKGQKPRFTTH--------IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191 V S+ + + H + + + F TV D ++W +G+ Sbjct: 4058 AVKPSRHVRGELSEHLILPKFIDVTEVSPYRVSYDGDFTLTVKLSGSGD--VQWMKDGEV 4115 Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251 + S R D +L I D G Y C NK G D TR+ + LE Sbjct: 4116 IEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAGFD-TRSF-------DIGLED 4167 Query: 3252 LQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDD 3311 L+P + A PS A P ++ ++ + R+ Sbjct: 4168 LRPHTFA-------------YEPSELVA--PYYLEDGVTAFQMTDAGDVKLTVRVRGKPK 4212 Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371 P +K W N + + + + + L I + + G Y+ +ATN+ G ++ + N Sbjct: 4213 PTVK--WTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGGINTKRFN 4270 Query: 3372 LKC----TSKENLILDSQLPRGMEGGLEKLQ 3398 + T+ ++ D + PR ++ G+ + Sbjct: 4271 VDIEWDETTTTRVVDDREAPRFLDDGISSYE 4301 Score = 43.2 bits (97), Expect = 0.005 Identities = 46/195 (23%), Positives = 78/195 (40%), Gaps = 8/195 (4%) Query: 3054 FKDIVDISEGQIAHY-EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILG 3112 F D+ ++S ++++ + +L S ++W +G+ IE S R + +L ILG Sbjct: 4078 FIDVTEVSPYRVSYDGDFTLTVKLSGSGDVQWMKDGEVIEDSKRYVIRQDDDLHMLTILG 4137 Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA----- 3167 D GTY C TNK G S + D + + L+DG +A Sbjct: 4138 ATEDDLGTYKCVVTNKAGFDTRSFDIGLEDLRPHTFAYEPSELVAPYYLEDGVTAFQMTD 4197 Query: 3168 --HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 + TV P ++W N +P+ S+ + + L I D G Y Sbjct: 4198 AGDVKLTVRVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVI 4257 Query: 3226 AYNKYGEDFTRATIN 3240 A N+ G + R ++ Sbjct: 4258 ATNEGGINTKRFNVD 4272 Score = 43.2 bits (97), Expect = 0.005 Identities = 46/198 (23%), Positives = 74/198 (37%), Gaps = 29/198 (14%) Query: 1478 VEWFKNGQPVT-IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536 V W K+ +P+T H ++D Y + I +D GIY C A N VGT + Sbjct: 4532 VTWTKDSKPITETDHIQVSVYDDTYTLI-IKSPTDKDEGIYKCTASNSVGTSSQMFDVDI 4590 Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596 + T +++S ++ D +M DE + + + E+K Sbjct: 4591 KGTDWMLKSKDDD-----FPSFVDEDDVEAFEMTDEGSIRMTVIVRGKPKPEVK------ 4639 Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656 W ++KPL S L I S +D GTY C A+N Sbjct: 4640 ----------------WSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVN 4683 Query: 1657 ALGEAVTSGIAIVHSKKS 1674 G + S + V+++ S Sbjct: 4684 RAGTNIRSFVVNVNTEDS 4701 Score = 42.7 bits (96), Expect = 0.007 Identities = 43/178 (24%), Positives = 70/178 (39%), Gaps = 18/178 (10%) Query: 2572 SVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPE 2631 +V G+ MC AI ++D+ RP ++ ++L+ ++ E Sbjct: 1950 TVGGGPGGIEMCVAIQDFEDEFGDFSLKKKESVIVLDKISRPGMYKVVRLRSDG-SRGDE 2008 Query: 2632 MFVDTGVQQA--------------PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIE 2677 M+V V Q P F LK + + EG+ L+ ++ + N+K Sbjct: 2009 MWVPPNVLQKKRSTAEIMMGDIQPPFFQKPLKDKE-VKEGKPFKLDVKITALPEANVK-- 2065 Query: 2678 WFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 W K+G L G K+ L I +D G Y C+A N G A + A I +E Sbjct: 2066 WLKDGEPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVE 2123 Score = 42.7 bits (96), Expect = 0.007 Identities = 35/148 (23%), Positives = 61/148 (41%), Gaps = 5/148 (3%) Query: 1791 LGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQL 1850 +G+ + TL + KA ++ + E+ R + + P F + L Sbjct: 2147 IGQEPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSAL 2206 Query: 1851 NGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS-GHRYRTSNDFGFA-ALDILT 1908 +++EG + + P P V+W+ +GK + HR G L I Sbjct: 2207 RD-IEVNEGNTVTLRIHVTGSPKPE--VDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKE 2263 Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 G D+G+Y CKA N+ G+ SS ++V Sbjct: 2264 ARGSDTGKYLCKAYNSAGEVTSSCNVDV 2291 Score = 42.7 bits (96), Expect = 0.007 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 3/110 (2%) Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599 G TV LT A+ GNPP F D+ ++E FE ++ ++W+ N Sbjct: 2476 GQDDTVAELTV-AKRGNPPFFVKELVDIDVTEGGHERFE--VVVDGYPKPEIDWYKNDIL 2532 Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 + G + L + + G TCKA N G+A SC +Q+ Sbjct: 2533 IRPGPKFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQI 2582 Score = 42.7 bits (96), Expect = 0.007 Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 3/101 (2%) Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474 ++G P F L +I+ + EG + FE + P +++WY N ++ G +F Sbjct: 2488 KRGNPPFFVKELVDID-VTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEH 2544 Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 L + PE++G+ C+A N+ G+A+ + +++ K Sbjct: 2545 GDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585 Score = 42.3 bits (95), Expect = 0.009 Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 1/101 (0%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P F K +D++V EGK + D ++T P V W + D + +H + L+ Sbjct: 2033 PFFQKPLKDKEVKEGKPFKLDVKITALPEANVKW-LKDGEPLKPGDHFKTERHGDTYFLI 2091 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPK 492 I + D G C A N +G + + + V ++ P+ Sbjct: 2092 IPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPE 2132 Score = 42.3 bits (95), Expect = 0.009 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 6/103 (5%) Query: 2920 EHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLT--SDFGFVTLDLVDVY 2977 + ++ EG+ L+ ++ P+ ++W +G+ L+ G FK D F+ + DV Sbjct: 2041 DKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTYFLIIPEADV- 2097 Query: 2978 ERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTE 3020 D G Y C+A N G A T + + S D E P+ E Sbjct: 2098 -EDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQME 2139 Score = 42.3 bits (95), Expect = 0.009 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 PP+F D+ ++E S F+ ++ +V W+HNGK + V ++D Sbjct: 2299 PPKFERNLKDITIAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSS 2356 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 L + +G YTC A N G+ + +L + Sbjct: 2357 LILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389 Score = 42.3 bits (95), Expect = 0.009 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 2/104 (1%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP F+ L + EGG FE ++ G P +I+W KN I +F + + Sbjct: 2492 PPFFVKELVDIDVTEGGHERFEVVVD--GYPKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQ 739 L + +++G+ TC+A ++ G A + + + + +Q Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTIPPKITQ 2593 Score = 42.3 bits (95), Expect = 0.009 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDI 4169 PP FV + V EG RF V G+PKP + W N I G ++ + G +H I Sbjct: 2492 PPFFVKELVDIDVTEGGHERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTLI 2551 Query: 4170 PK-TRQYDTGKI 4180 K R +TGK+ Sbjct: 2552 VKDCRPEETGKL 2563 Score = 41.9 bits (94), Expect = 0.012 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 2/75 (2%) Query: 1586 NVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPE 1645 +++I EG+ A FE R+ + +VEW + +P+K G RF L I+ Sbjct: 3068 SLQIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLN 3125 Query: 1646 DSGTYTCRAINALGE 1660 D G YTC A + G+ Sbjct: 3126 DEGEYTCVATSKAGK 3140 Score = 41.9 bits (94), Expect = 0.012 Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 4/102 (3%) Query: 1972 SFVVEKPQFGK--PIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029 +F+ P F + P + EG + EAT++ P VEW+ + P+ + + Sbjct: 3246 TFIPVPPHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLH 3303 Query: 2030 YDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071 +L I +D+G Y C ATN G A T ++ ++A Sbjct: 3304 RSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRTYNIDIEA 3345 Score = 41.9 bits (94), Expect = 0.012 Identities = 83/347 (23%), Positives = 131/347 (37%), Gaps = 51/347 (14%) Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911 GP ++E E +I+ P P++R WY + L R + + + I Sbjct: 3754 GPLSITEDGDLVLEVKIKGEPLPDVR--WYKDDVPLDETCRIKIDAEGDIQIVTIKDANK 3811 Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDD 1971 EDS +T N+ G A+ ++V ES + K+Q KR D+ Sbjct: 3812 EDS-VFT-NITNDFGTAIRRFSIDV------------ESVMPKLQGF-----VKR---DE 3849 Query: 1972 SFVVEKPQFG--KPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029 F PQF + + EVT + L+ +T +P V W+ +G PV Sbjct: 3850 DF----PQFVNVEGVSPFEVTSEGDIKLQTRVTGFPEPD--VSWFKDGIPVVPNEHIVYH 3903 Query: 2030 YDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQ 2089 L I GTY C ATN G + +V ++G + + Q Sbjct: 3904 IRDDVHILIIKSPTPLYAGTYKCVATNRRG--TNSRDFEVTIETGEAAEHIT------FQ 3955 Query: 2090 ELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149 + E+ R + IE+ P +T +EGD + +V P IDWF +G Sbjct: 3956 QDEETVRAQFIEKGPYAPVPFEIT--------EEGD---VKLQVRICGIPFPEIDWFKDG 4004 Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNT 2196 + + + T D + I +D+G Y C N G+A T Sbjct: 4005 RHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGKATRT 4051 Score = 41.9 bits (94), Expect = 0.012 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 2/75 (2%) Query: 87 GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146 G+ + +RG P P V W++ PL + M + T +L+IK D G Y C Sbjct: 4622 GSIRMTVIVRGKPKPEVKWSKDDKPLTPNSNIVMEEMDDT--YTLVIKSPSSDDRGTYKC 4679 Query: 147 TARNQYGEAICSVYI 161 TA N+ G I S + Sbjct: 4680 TAVNRAGTNIRSFVV 4694 Score = 41.5 bits (93), Expect = 0.016 Identities = 40/145 (27%), Positives = 61/145 (42%), Gaps = 9/145 (6%) Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTT--GKPGIVYDSQLPKHMKSIEKIREMEASWQVT 4097 PED + + ++T + + + T GK G +D Q + +K E ++ Sbjct: 2131 PEDEPQQMEQSTKTIAIGQEPPAVTLTLDGKAG--FDFQAVE-LKIPHPDEIAEEDLRID 2187 Query: 4098 PEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGS 4155 EQ K PP F S + V EG VTG PKP V W +G + + Sbjct: 2188 VEQTAALPKP-IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHR 2246 Query: 4156 RYKLTYDG-MYHFDIPKTRQYDTGK 4179 R+++ G +Y I + R DTGK Sbjct: 2247 RFEVGCVGEVYTLVIKEARGSDTGK 2271 Score = 41.5 bits (93), Expect = 0.016 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 9/97 (9%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV- 2700 P F + L+ + + EG V L V P +++WFK+G ++ + F+ G V Sbjct: 2200 PEFKSALRDIE-VNEGNTVTLRIHVTGSPKP--EVDWFKDGKPVSGLPHRR--FEVGCVG 2254 Query: 2701 ---TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 TL I R D+G Y CKA N GE S+ ++ + Sbjct: 2255 EVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDV 2291 Score = 41.5 bits (93), Expect = 0.016 Identities = 43/168 (25%), Positives = 72/168 (42%), Gaps = 5/168 (2%) Query: 2240 SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY 2299 +PP FV EL V EG FE V+ P I++Y N ++ +F I + Sbjct: 2491 NPPFFVKELVDID-VTEGGHERFEVVVDGYPKPE--IDWYKNDILIRPGPKFDIKEHGDH 2547 Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359 +L ++ C PE+ G+ + KA N+ G + + + K +QR L Sbjct: 2548 HTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTIPPKITQRLHDLSIDAGKTVN 2607 Query: 2360 EPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPT 2407 K PEP+ + + + + N D + + +T+H L+ VG T Sbjct: 2608 LTVKFFGTPEPLVKWF-MDDEEITNEDGV-DIETSHCTSSLVLVGVDT 2653 Score = 41.5 bits (93), Expect = 0.016 Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 7/124 (5%) Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 V+W +G+ I+ R+ + D L +L +D G Y C TN+ G S + + Sbjct: 4107 VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAGFDTRSFDIGLE 4166 Query: 1404 AKKDLILESQHPSGLEKIQYLED-TSRYKKTDIIDESVTIKPRFVTRP-----KSIENVI 1457 + + PS L YLED + ++ TD D +T++ R +P K+ E V+ Sbjct: 4167 DLRPHTF-AYEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRVRGKPKPTVKWTKNDEPVV 4225 Query: 1458 EGQH 1461 H Sbjct: 4226 PSSH 4229 Score = 41.5 bits (93), Expect = 0.016 Identities = 77/356 (21%), Positives = 136/356 (38%), Gaps = 46/356 (12%) Query: 1278 DTQNEQAIEQIQLLEDAARRTKQVREDITVM--QAPQFSRALHNIETVEGTNV-HLECRL 1334 +T + I Q + + AR K + ED+ Q P F ++ E T ++ + Sbjct: 4813 ETMSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIET-DEVKPFEVTEEGDIKMTV 4871 Query: 1335 QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEA 1394 + G VEW + +P+ + + E D +L + D G+YT + TN +G Sbjct: 4872 KVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSG 4931 Query: 1395 VTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSI- 1453 + ++V EDT+ T + + T++P+F+ + Sbjct: 4932 TRTFDVKV----------------------EDTT----TSLFEG--TVRPKFIEDDSFVP 4963 Query: 1454 -ENVIEGQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLI 1510 E+ EG +V K+ +PV + V W K+ +PV R H L I + Sbjct: 4964 FESTEEG-NVRLSVKITGKPVPE----VSWTKDEKPVHKIQNIRLDHQDDIYTLTIREAT 5018 Query: 1511 AEDSGIYTCRAVNLVG--TDEVSCRLTCRSTTDIVRSTQNEA-GLEQIQVLEDRSKYHRT 1567 DSG Y C N G T S + + + + T+ E LE+ ++ Sbjct: 5019 PNDSGSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEV 5078 Query: 1568 DMVDEVTTQAPICTTSLKNVEIK--EGQRAHFERRLIPVSDATLKVEWYHNNKPLK 1621 + E T+ I +K + K E + FE + + + + E KPL+ Sbjct: 5079 KPLVETITRKEIKVEEVKPKKGKPTEREAKPFEEKPLIEEELPISAEKVVEEKPLE 5134 Score = 41.5 bits (93), Expect = 0.016 Identities = 42/195 (21%), Positives = 71/195 (36%), Gaps = 28/195 (14%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 VEW +++P+ S S T +L I D G YT + N +G SG Sbjct: 4881 VEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG----SGTRTFD 4936 Query: 1671 SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHF 1730 K S EG + R +ED S S ++ + + T Sbjct: 4937 VKVEDTTTSLFEGTV-RPKFIEDDSFVPFESTEEGNVRLSVKIT---------------- 4979 Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790 G P V W ++ P+ + H L ++ P DSG+Y C N+ Sbjct: 4980 -------GKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTND 5032 Query: 1791 LGEAVTSSTLFVQSK 1805 G++ + ++ ++ + Sbjct: 5033 AGKSTRTFSVEIEGE 5047 Score = 41.1 bits (92), Expect = 0.021 Identities = 49/181 (27%), Positives = 71/181 (39%), Gaps = 20/181 (11%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV-I 3616 P+F +++ +S + ECR+ +V WF + K + SR G V + Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCV 2453 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676 L I GV D G Y C ATN G+ +L V R P F I + Sbjct: 2454 LTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN-------PPFFVKELVDID-VT 2505 Query: 3677 ETLHKREEITIED-EKPNPPRFTVEI----KDNIDVPEGGPVHF----DCRVEPVGDPTM 3727 E H+R E+ ++ KP + +I D+ E G H DCR E G T Sbjct: 2506 EGGHERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTLIVKDCRPEETGKLTC 2565 Query: 3728 R 3728 + Sbjct: 2566 K 2566 Score = 41.1 bits (92), Expect = 0.021 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 27/220 (12%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576 P E+ E + R+ + P + +W+ +G L + T D T+ I Sbjct: 3975 PFEITEEGDVKLQVRICGIPFPEI--DWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIK 4032 Query: 2577 DAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDT 2636 D G Y C N AG +A++P + +L E + +P+ F+D Sbjct: 4033 DTGKYKCIIKNIAGKATRTFDVDI--------EAVKPSRHVRGELSEHLI--LPK-FIDV 4081 Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696 T + Y +G L ++ D ++W K+G + R D Sbjct: 4082 ---------TEVSPYRVSYDGDFT-LTVKLSGSGD----VQWMKDGEVIEDSKRYVIRQD 4127 Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 L L+I DD G Y C TN G + I +ED Sbjct: 4128 DDLHMLTILGATEDDLGTYKCVVTNKAGFDTRSFDIGLED 4167 Score = 40.7 bits (91), Expect = 0.028 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 3/87 (3%) Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166 Q P F L E +KEG + ++ + P + W +G+ ++ G ++T Sbjct: 2031 QPPFFQKPLKDKE-VKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087 Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEA 2193 L I ED G Y C+A N G A Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRA 2114 Score = 40.7 bits (91), Expect = 0.028 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 5/95 (5%) Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT-IGHRFRPIHDFG 1500 I P F + + IE V EG V ++ +V+WFK+G+PV+ + HR + G Sbjct: 2198 IPPEFKSALRDIE-VNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVG 2254 Query: 1501 YV-ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 V L I + D+G Y C+A N G SC + Sbjct: 2255 EVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNV 2289 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233 K P F + L + ++EG + + ++ G P +V W+HNG+ V +D Sbjct: 2297 KEPPKFERNLKDIT-IAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDDE 2353 Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271 +L ++H +G+YT A N +G ++A + + E Sbjct: 2354 HSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHITE 2391 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 3/98 (3%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA- 1769 P F + ++ ++ E R+ G P+ +V W ++ I +R + G V Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCV 2453 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807 L ++ V P+D G+Y C A N G+ T + L V + + Sbjct: 2454 LTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491 Score = 40.7 bits (91), Expect = 0.028 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 4/97 (4%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFG-FA 1902 P+F +L +S G + ECR+ P P +V W+ + K ++ R+ G Sbjct: 2396 PKFAERLTN-VSISSGDTIVLECRVTGKPRP--QVAWFKDDKEIRQDSRFSFETRPGDVC 2452 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 L I V +D G Y C A N GQ + L V + Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKR 2489 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 2/96 (2%) Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970 P + + + + EG H +V P +I+WY N ++ G +F + T Sbjct: 2492 PPFFVKELVDIDVTEGG--HERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549 Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006 L + D ++G TCKA N G+A S V K Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585 Score = 40.7 bits (91), Expect = 0.028 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 6/120 (5%) Query: 2344 SQRPEGLEKIRELESAEPFKRPE--IPEPVT---RQRPVFTQPLQNIDNIQEGQTAHFDC 2398 S+ + KI + E A RPE I E V +Q P+F + + + + Sbjct: 4811 SEETMSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIET-DEVKPFEVTEEGDIKM 4869 Query: 2399 RLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 + G P VEW ++++ + S I T + S+TI DEG+Y + +N +G Sbjct: 4870 TVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG 4929 Score = 40.3 bits (90), Expect = 0.037 Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 3/124 (2%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566 +P F Q E+ EG+ + ++ + P +W +G LK G F+T Sbjct: 2031 QPPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTY 2088 Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAM 2626 L I D G Y C+A+N AG + P+ EQ K A+ Sbjct: 2089 FLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQ-STKTIAI 2147 Query: 2627 NKVP 2630 + P Sbjct: 2148 GQEP 2151 Score = 40.3 bits (90), Expect = 0.037 Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 12/155 (7%) Query: 3420 PVFTVPLSNIE-NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478 P FT I + EG + FEA T + P VEW+ + + S + Sbjct: 3252 PHFTEEAPKIPTDFEEGGDITFEA--TVSGRPRPDVEWHKDEAPISESSHYHLHRSNDTY 3309 Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIAA 3537 L I P+DSG Y C A N G A T NI +E+ PKG ID + Sbjct: 3310 SLTIRGVGPDDSGAYTCTATNECGMAKRT--------YNIDIEASEPKGSTPQFIDLMQP 3361 Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSEN 3572 +E G T + P + L L EN Sbjct: 3362 VEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKEN 3396 Score = 40.3 bits (90), Expect = 0.037 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 G PT + W ++EK+I ++ T D G S+T+ +ED G+Y C A G Sbjct: 4421 GRPT--ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDG 4473 Score = 40.3 bits (90), Expect = 0.037 Identities = 48/239 (20%), Positives = 89/239 (37%), Gaps = 21/239 (8%) Query: 3014 QHPKGTEGLEKIQNLEDSLRKEPGQQP---DDDTGRPPEFTTVFKDIVDISEGQIAHYEA 3070 Q K E +N+ + + +P Q+P + D +P E T EG I + Sbjct: 4822 QDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVT---------EEGDI---KM 4869 Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130 ++ TG +EW + + + + I+ + L I +D G Y+ + TN G Sbjct: 4870 TVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG 4929 Query: 3131 QAE--ISVKLECVDKSKGQ---KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185 VK+E S + +P+F + + + + +V P ++ W Sbjct: 4930 SGTRTFDVKVEDTTTSLFEGTVRPKFIED-DSFVPFESTEEGNVRLSVKITGKPVPEVSW 4988 Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244 + +P+ I+ L I +DSG Y C N G+ ++ G+ Sbjct: 4989 TKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGE 5047 Score = 39.9 bits (89), Expect = 0.049 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 4/87 (4%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPS--GTRYKSTHDFSYVSL 2833 F S L +I EG+ + +V S P +++WF + KP+ R++ +L Sbjct: 2202 FKSALRDIEVNEGNTVTLRIHVTGSPKP--EVDWFKDGKPVSGLPHRRFEVGCVGEVYTL 2259 Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTS 2860 I D+G Y CKA NS G T+S Sbjct: 2260 VIKEARGSDTGKYLCKAYNSAGEVTSS 2286 Score = 39.9 bits (89), Expect = 0.049 Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 5/112 (4%) Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288 + R+ + E I P +F L + + G T EC+V P ++ ++ + K ++ Sbjct: 2384 AARLHITELAIQP-KFAERLTNVS-ISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQD 2439 Query: 2289 ARFHITFDFGYVS-LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGS 2339 +RF G V L I+ P+D G Y A N G + +TV +G+ Sbjct: 2440 SRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491 Score = 39.9 bits (89), Expect = 0.049 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 2/85 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F+ L +I EG + FE V+ P +I+W+ N+ + G ++ + +L + Sbjct: 2495 FVKELVDIDVTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEHGDHHTLIV 2552 Query: 2836 THTYEEDSGIYTCKATNSKGSATTS 2860 E++G TCKA NS G A S Sbjct: 2553 KDCRPEETGKLTCKARNSAGQAICS 2577 Score = 39.9 bits (89), Expect = 0.049 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P F+ + ++ EG+ A F+ R+ +T WY + I R + Y D + Sbjct: 3156 PEFVRKISNI-ELTEGEIARFDVRITGTPAPEVT--WYKDEVPIEDGGRFEIYSDDDKHS 3212 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 L I D+G Y+ A N AG+A +T+ Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQASCYGELTI 3245 Score = 39.5 bits (88), Expect = 0.065 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 2/88 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 FI +++ EG FE V P ++EW + +P+ G R++ + L I Sbjct: 3062 FIVKPSSLQIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEFEKDRSVLTI 3119 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 D G YTC AT+ G + S L Sbjct: 3120 IDAKLNDEGEYTCVATSKAGKDSCSVEL 3147 Score = 39.5 bits (88), Expect = 0.065 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 3/83 (3%) Query: 491 PKFVER-FSTL--NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547 P F+++ F T V E V L R G P P + W KD II +P + + T Sbjct: 3644 PHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVHT 3703 Query: 548 LDIPRAKASDAAWYQCTAQNVAG 570 L I D Y+ A N G Sbjct: 3704 LVINSPNQDDIGQYKVIASNHRG 3726 Score = 39.5 bits (88), Expect = 0.065 Identities = 18/51 (35%), Positives = 27/51 (52%) Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995 I W + K++ Q ++F T D G +L +V E D G+YTC A G + Sbjct: 4425 ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRS 4475 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 3/93 (3%) Query: 3147 QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGF 3206 Q P F +++ E +K+G+ + + + P+ ++W +G+P++ KT Sbjct: 2031 QPPFFQKPLKDKE-VKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087 Query: 3207 VVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239 L I D G Y C A N G T A I Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADI 2120 Score = 39.1 bits (87), Expect = 0.086 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828 +P+F L ++ + G E ++T P +V W+KD + I SR + G V Sbjct: 2395 QPKFAERLTNVS-ISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDV 2451 Query: 829 S-LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 L I + +D GSY A N G+ + A + VA R Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKR 2489 Score = 39.1 bits (87), Expect = 0.086 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 4/104 (3%) Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 PP F+ ++ V E RFE V+ PK I+WY+N L+ G ++ + Sbjct: 2492 PPFFVKELVDIDVTEGGHERFEVVVDGY--PKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTK--ATISCKKLPDIILQ 3930 L + E++G+ C+A N G+ I+ K +P I Q Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTIPPKITQ 2593 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 4/105 (3%) Query: 1709 QAPVF--TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 Q P+F T +K V E ++ G PK VEWL++ P+ + + + + Sbjct: 4846 QEPIFIETDEVKPFEVTEEGDIKMTVKV--TGKPKPSVEWLKDDRPVLSDSHIKMTEEDD 4903 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLE 1811 +L ++ D G YT + N++G + + V+ + E Sbjct: 4904 IYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFE 4948 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 5/96 (5%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKS-GSRFTETNNFGFV- 1635 P ++L+++E+ EG R+ +V+W+ + KP+ R E G V Sbjct: 2200 PEFKSALRDIEVNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257 Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTS-GIAIVH 1670 L I D+G Y C+A N+ GE +S + ++H Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLH 2293 Score = 38.7 bits (86), Expect = 0.11 Identities = 18/53 (33%), Positives = 26/53 (49%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162 PP F +T+ EG RF +VTG P+P+V W NG + + +D Sbjct: 2299 PPKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHD 2351 Score = 38.7 bits (86), Expect = 0.11 Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P F + L +ID + EG F+ ++ G P +++W++N+ LI + + + Sbjct: 2493 PFFVKELVDID-VTEGGHERFE--VVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549 Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459 + + R E+ G C+A N G+ Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQ 2573 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 3/84 (3%) Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031 PP FV +I S L E E +F+ ++ G P +V W+ + P+ RF D Sbjct: 3155 PPEFVRKI-SNIELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIYSDDDKH 3211 Query: 4032 AMNFGWVYPEDSGEYLCRATNLYG 4055 ++ D+G Y C+ATN G Sbjct: 3212 SLVIRDCALSDTGSYSCKATNEAG 3235 Score = 38.7 bits (86), Expect = 0.11 Identities = 18/51 (35%), Positives = 25/51 (49%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 VEW+ + P+ S + + +L I P+DSG YTC A N G A Sbjct: 3285 VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAYTCTATNECGMA 3335 Score = 38.7 bits (86), Expect = 0.11 Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 4/108 (3%) Query: 1841 NQAPRFITQL--NGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND 1898 ++ P FI + P +++E E R+ +P P+ V+W + +V+ S + S+ Sbjct: 3641 DERPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPS--VQWLKDDEVIISSPHFMVSSH 3698 Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946 L I + +D G+Y A N+ G A + +NV+ +R S Sbjct: 3699 ADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNVEGANDEMRAS 3746 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 2/89 (2%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712 +L E V L +V + P + W K+ +T ++ + TL I S + D Sbjct: 4511 QLTEEGDVKLMVRVAGKPKPT--VTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDE 4568 Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHWLL 2741 GIY C A+N +G + + I+ W+L Sbjct: 4569 GIYKCTASNSVGTSSQMFDVDIKGTDWML 4597 Score = 38.7 bits (86), Expect = 0.11 Identities = 53/251 (21%), Positives = 101/251 (40%), Gaps = 22/251 (8%) Query: 4215 RPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKN 4274 +P + T+ + E + EE + + V++ +P KP KE + E + K K Sbjct: 5096 KPKKGKPTEREAKPFEEKPLIEEELPISAEKVVEEKPLEKPIARKEKKVEKVKPKKEKPT 5155 Query: 4275 EEYYNKLQE----------LENEQVIKESRLRE--STHQYAIPGDKVTSNTVAKSMAQRY 4322 E L+E + E+V++E L + + + + K + AQ Sbjct: 5156 EREAKPLEEKHLVEEKELPVSAEKVVEEKPLEKPITRKEDKVEEVKPKKEKPMEREAQHL 5215 Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEV--VGDKEITR 4380 E+ E+ +K + +KP + G+EV K+K T++E + +K + Sbjct: 5216 EEKPLLKEKELPVSAEKAIEEKPLEKPFTPKDKKGEEVKPKKEKPTEREAKPLEEKPLVE 5275 Query: 4381 K----ITSTETTE---IEHKAQTQERVVEGPVKPSKPPIFTKKMQPCR-VFEHEQARFEV 4432 K +++ + E +E +E+V E K KP + K + + + E ++ Sbjct: 5276 KDELPVSAEKVVEENPLEKPITRKEKVEEVKPKKEKPTVREAKSREVKPLVEEKELPVSA 5335 Query: 4433 EFDGEPLPLIK 4443 E E PL K Sbjct: 5336 EKAVEEEPLEK 5346 Score = 38.3 bits (85), Expect = 0.15 Identities = 20/70 (28%), Positives = 36/70 (51%) Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 V+ P+ K+ WY NGK+++ + D +L L+ SG YTC A N+ G+ Sbjct: 2321 VQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCVAENEVGQ 2380 Query: 2995 AFTSSTVYCT 3004 +++ ++ T Sbjct: 2381 VQSAARLHIT 2390 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 4/97 (4%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDFGLV 2700 P F L + + G + LE +V + P ++ WFK+ + +R T + Sbjct: 2396 PKFAERLTNVS-ISSGDTIVLECRVTGKPRP--QVAWFKDDKEIRQDSRFSFETRPGDVC 2452 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 L+I + DD G Y C ATN G+ + A + + R Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKR 2489 Score = 38.3 bits (85), Expect = 0.15 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 4/88 (4%) Query: 3826 VSTPPKFITQIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883 + PP F + + EG + FE V + P+ +EW+++ + Y Sbjct: 3248 IPVPPHFTEEAPKIPTDFEEGGDITFEATVSGR--PRPDVEWHKDEAPISESSHYHLHRS 3305 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFG 3911 SL I V +DSG Y C A N+ G Sbjct: 3306 NDTYSLTIRGVGPDDSGAYTCTATNECG 3333 Score = 37.9 bits (84), Expect = 0.20 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 4/97 (4%) Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499 + I+P+F R ++ ++ G + EC++ +V WFK+ + + RF Sbjct: 2392 LAIQPKFAERLTNV-SISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRP 2448 Query: 1500 GYVA-LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 G V L I + +D G Y C A N G D+ LT Sbjct: 2449 GDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELT 2485 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 2/87 (2%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 ++ EGQ E V K P IEW+ NG L++ R T + +L + D Sbjct: 3363 EVTEGQTATFECTV--KGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDE 3420 Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDN 3008 G Y C A N G+A ++ + D+ Sbjct: 3421 GNYKCVARNSFGKASCATELLVDEADS 3447 Score = 37.9 bits (84), Expect = 0.20 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 2/56 (3%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 G P V W ++ K I ++ I +D Y ++ I D+DEG+Y C ASN +G Sbjct: 4526 GKPKPTVTWTKDSKPITETDHIQVSVYDDTY-TLIIKSPTDKDEGIYKCTASNSVG 4580 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 4/84 (4%) Query: 72 PIFEQI--FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 PIF + K + G+ K K+ G P P V W + P++ + M E+ Sbjct: 4848 PIFIETDEVKPFEVTEEGDIKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKM--TEEDDIY 4905 Query: 130 SLLIKQIGPGDEGEYTCTARNQYG 153 SL I++ DEG YT N G Sbjct: 4906 SLTIREPTKSDEGMYTVKITNDVG 4929 Score = 37.9 bits (84), Expect = 0.20 Identities = 19/73 (26%), Positives = 32/73 (43%) Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855 +V+ + P ++ W + KP+ + H +L I DSG Y C TN G Sbjct: 4975 SVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAG 5034 Query: 2856 SATTSGSLRCTGD 2868 +T + S+ G+ Sbjct: 5035 KSTRTFSVEIEGE 5047 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 6/82 (7%) Query: 1057 EGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114 EG FEA V P+ D VEW+ + I+ ++ + +L I V +DSG Sbjct: 3267 EGGDITFEATVSGRPRPD----VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSG 3322 Query: 1115 VYTVVARNAAGEAQLSASMTVE 1136 YT A N G A+ + ++ +E Sbjct: 3323 AYTCTATNECGMAKRTYNIDIE 3344 Score = 37.5 bits (83), Expect = 0.26 Identities = 19/62 (30%), Positives = 27/62 (43%) Query: 2807 IEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866 I W + K + ++ T D SL + EED G+YTC A + G + LR Sbjct: 4425 ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSERRFDLRVE 4484 Query: 2867 GD 2868 D Sbjct: 4485 DD 4486 Score = 37.5 bits (83), Expect = 0.26 Identities = 19/59 (32%), Positives = 28/59 (47%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 V W KD +P+ + I L IKS T D G Y C A N++G ++ ++ I Sbjct: 4532 VTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGIYKCTASNSVGTSSQMFDVDI 4590 Score = 37.5 bits (83), Expect = 0.26 Identities = 59/306 (19%), Positives = 115/306 (37%), Gaps = 11/306 (3%) Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTGK 4179 + EEG R ++TG P P V W + + +L + D +Y I + D+G Sbjct: 4966 STEEGN-VRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGS 5024 Query: 4180 IEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQ 4239 + +++ +G +E ETE+E Sbjct: 5025 YKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEVKPLVET 5084 Query: 4240 VLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE--LENEQVIKESRLRE 4297 + +++ ++ E+KPK K E E + ++ EE E +E + + K +E Sbjct: 5085 ITRKEIKVE---EVKPKKGKPTEREAKPFEEKPLIEEELPISAEKVVEEKPLEKPIARKE 5141 Query: 4298 STHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKP--RIPDPSESTV 4355 + P + + AK + +++ + E+ V++K +KP R D E Sbjct: 5142 KKVEKVKPKKEKPTEREAKPLEEKHLVEEKELPVSAEKVVEEKPLEKPITRKEDKVEEVK 5201 Query: 4356 HGKEVHVAKQKQ--TQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIF 4413 KE + ++ Q +K ++ +KE+ + K T + VKP K Sbjct: 5202 PKKEKPMEREAQHLEEKPLLKEKELPVSAEKAIEEKPLEKPFTPKDKKGEEVKPKKEKPT 5261 Query: 4414 TKKMQP 4419 ++ +P Sbjct: 5262 EREAKP 5267 Score = 37.1 bits (82), Expect = 0.35 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 5/109 (4%) Query: 1031 KRTEEEVKI--TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088 KR+ E+ + Q P F PLK ++ EG+ + ++ + V+W +G+ + Sbjct: 2019 KRSTAEIMMGDIQPPFFQKPLKD-KEVKEGKPFKLDVKITALPEAN--VKWLKDGEPLKP 2075 Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137 + +T L I ED G Y A N AG A A + VE+ Sbjct: 2076 GDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVES 2124 Score = 37.1 bits (82), Expect = 0.35 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 4/85 (4%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR-TTHDFGF 2565 +P F + LT S + G E RV G P + W+ + E++ SRF T Sbjct: 2395 QPKFAERLTNVS-ISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDV 2451 Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590 L I V +D G Y C A N AG Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAG 2476 Score = 37.1 bits (82), Expect = 0.35 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 I EG+ A F+ R+ G P +VEW R+ + I+ R + +TI + DEG Sbjct: 3071 IMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEG 3128 Query: 2448 VYMCRASNLLGE 2459 Y C A++ G+ Sbjct: 3129 EYTCVATSKAGK 3140 Score = 36.7 bits (81), Expect = 0.46 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 3/104 (2%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P FV I+ V EG H FE ++ +++W+KN + G +F + Sbjct: 2493 PFFVKELVDID-VTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEHGDHHT 2549 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547 L + D E++G TC+A N G SC + T + TQ Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTIPPKITQ 2593 Score = 36.7 bits (81), Expect = 0.46 Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 3/86 (3%) Query: 3972 PPRFVTQIQS-QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030 PP F + T E FE ++ G P VEW + P+ + + Sbjct: 3251 PPHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDT 3308 Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGM 4056 ++ V P+DSG Y C ATN GM Sbjct: 3309 YSLTIRGVGPDDSGAYTCTATNECGM 3334 Score = 36.7 bits (81), Expect = 0.46 Identities = 18/61 (29%), Positives = 28/61 (45%) Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 T+ W + K IT N+ D G +L + ED G+YT +A G ++ + V Sbjct: 4424 TITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSERRFDLRV 4483 Query: 1136 E 1136 E Sbjct: 4484 E 4484 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 P F L +I + EG + F+ ++T + +P KV WY NGK ++ D Sbjct: 2300 PKFERNLKDI-TIAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHVDIVHDDEHSS 2356 Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 L + + SG+Y C A N G+ + A + + Sbjct: 2357 LILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389 Score = 36.3 bits (80), Expect = 0.61 Identities = 17/61 (27%), Positives = 30/61 (49%) Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 I W K+ +T + T D G+ +L++ +D G+YTC A G + +++E Sbjct: 4425 ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSERRFDLRVE 4484 Query: 2736 D 2736 D Sbjct: 4485 D 4485 Score = 36.3 bits (80), Expect = 0.61 Identities = 39/168 (23%), Positives = 66/168 (39%), Gaps = 22/168 (13%) Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP------------QGMSGEKIKEL 3811 D G Y C ++ +G +T T + + + P + MS KI + Sbjct: 4764 DTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEETMSVTKILQD 4823 Query: 3812 ERGRISDAPKE---EPIVSTP---PKFI--TQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863 E+ P++ E ++S P P FI ++K V E ++ +V K PK + Sbjct: 4824 EKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVTGK--PKPSV 4881 Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 EW ++ + + S + + SL I D G Y + ND G Sbjct: 4882 EWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG 4929 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 5/86 (5%) Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI-TKTHDFG 2432 Q P F +PL++ + ++EG+ D ++ + P V+W ++ + ++ T+ H Sbjct: 2031 QPPFFQKPLKDKE-VKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458 Y + I EDEG Y C A N G Sbjct: 2088 YF-LIIPEADVEDEGRYRCEAVNNAG 2112 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 3/96 (3%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P F + D I + EGG FE ++ G ++W K+ + + + + Sbjct: 2493 PFFVKELVD-IDVTEGGHERFEVVVD--GYPKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 L +K + G TC+A N+ GQA S + I K Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585 Score = 35.5 bits (78), Expect = 1.1 Identities = 15/49 (30%), Positives = 24/49 (48%) Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 ++W +G+V+E R+ + D L ++ E D G Y C NK G Sbjct: 4107 VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAG 4155 Score = 35.5 bits (78), Expect = 1.1 Identities = 45/204 (22%), Positives = 85/204 (41%), Gaps = 10/204 (4%) Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279 E ++ T EK EE + + LK K + E E E SV++ E+ Sbjct: 5605 EEKPLEKPITRKEKKVEEVKPKTEKPTEREAKPLKEKPLVE-EKELTVSVEKAVEEK--- 5660 Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339 LE KE ++ E + P ++ + K + + E + + V E+ ++K Sbjct: 5661 ---PLEKPITRKEKKVEEVKPKKEKPTEREAKSLDKKPLVEEKELPVSAKKAVEEKPLEK 5717 Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI-TSTETTEIEHKAQTQE 4398 +T++ + + + AK + +K +V +KE+T + + E +E +E Sbjct: 5718 PITREEKKVEEVKPKTEKPTEREAKPLK-EKPLVEEKELTVSVEKAVEEKPLEKPITRKE 5776 Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRV 4422 + VE VKP K ++ +P V Sbjct: 5777 KKVE-EVKPKKEKPTEREAKPREV 5799 Score = 35.1 bits (77), Expect = 1.4 Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 12/170 (7%) Query: 3900 GEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR-GMK-----RSEALTQMEATIKKY 3953 G +C A+ DF ++F S KK +I+ +++ R GM RS+ E + Sbjct: 1957 GIEMCVAIQDFEDEF--GDFSLKKKESVIVLDKISRPGMYKVVRLRSDGSRGDEMWVPPN 2014 Query: 3954 TSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG 4013 + + ++ D QPP F ++ + + E + K + ++ + + N+K W +G Sbjct: 2015 VLQKKRSTAEIMMGDI-QPPFFQKPLKDK-EVKEGKPFKLDVKITALPEANVK--WLKDG 2070 Query: 4014 KPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063 +PL + F + ED G Y C A N G T+A I Sbjct: 2071 EPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADI 2120 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 4/100 (4%) Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101 +P+F L + I G + E RV + V W+ + K+I +R G V Sbjct: 2395 QPKFAERLTNVS-ISSGDTIVLECRVTGKP--RPQVAWFKDDKEIRQDSRFSFETRPGDV 2451 Query: 1102 A-LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140 L I V +D G Y +A N AG+ A +TV R + Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491 Score = 35.1 bits (77), Expect = 1.4 Identities = 16/47 (34%), Positives = 23/47 (48%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY 4157 P F V++ G+ CRVTG P+P+V W + I SR+ Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRVTGKPRPQVAWFKDDKEIRQDSRF 2442 Score = 35.1 bits (77), Expect = 1.4 Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 2/71 (2%) Query: 83 FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142 F A FE ++ G P P V W + + +++ R + ++L ++ DEG Sbjct: 2848 FLADNKAIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRL--DDEG 2905 Query: 143 EYTCTARNQYG 153 E CTA N G Sbjct: 2906 EIKCTATNSAG 2916 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984 EG + E V + PD +EW+ + + + S + L +L + V DSG Y Sbjct: 3267 EGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAY 3324 Query: 2985 TCKAYNKRGEA 2995 TC A N+ G A Sbjct: 3325 TCTATNECGMA 3335 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%) Query: 87 GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146 G+ K + ++ G P P VSW + P+V N++ + Y+ + L+IK P G Y C Sbjct: 3869 GDIKLQTRVTGFPEPDVSWFKDGIPVVP-NEHIV-YHIRDDVHILIIKSPTPLYAGTYKC 3926 Query: 147 TARNQYG 153 A N+ G Sbjct: 3927 VATNRRG 3933 Score = 35.1 bits (77), Expect = 1.4 Identities = 16/49 (32%), Positives = 25/49 (51%) Query: 2410 VEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 V+W ++ ++IEDS R D +TI ++D G Y C +N G Sbjct: 4107 VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAG 4155 Score = 35.1 bits (77), Expect = 1.4 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 4/74 (5%) Query: 82 RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDE 141 +F G+ K +G PT ++W + + + + NK+ + E G SL + + D Sbjct: 4406 KFTSEGDVTMTVKTKGRPT--ITWMKDEKIITQDNKFL--FTEDDGIYSLTVVKPTEEDR 4461 Query: 142 GEYTCTARNQYGEA 155 G YTC A G + Sbjct: 4462 GLYTCIAETTDGRS 4475 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/103 (20%), Positives = 43/103 (41%) Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771 +++P Q ++ V E + ++T K KP+++WL++ + +M Sbjct: 4841 LSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMTE 4900 Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 E + L I + D G +T + T G + + V+ T Sbjct: 4901 EDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTT 4943 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 2651 YDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRND 2710 ++ EG +V L ++ + P ++ W K+ + ++ + TL+I + Sbjct: 4964 FESTEEG-NVRLSVKITGKPVP--EVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPN 5020 Query: 2711 DSGIYTCKATNLLGEAVSTASIKIE 2735 DSG Y C TN G++ T S++IE Sbjct: 5021 DSGSYKCTLTNDAGKSTRTFSVEIE 5045 Score = 35.1 bits (77), Expect = 1.4 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 3/86 (3%) Query: 3430 ENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPED 3489 E+ EG N ++T P +V W + K + R L I P D Sbjct: 4965 ESTEEG-NVRLSVKITGKPVP--EVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPND 5021 Query: 3490 SGEYLCRAYNNYGEAVTTASMKVQGK 3515 SG Y C N+ G++ T S++++G+ Sbjct: 5022 SGSYKCTLTNDAGKSTRTFSVEIEGE 5047 Score = 34.7 bits (76), Expect = 1.9 Identities = 16/52 (30%), Positives = 26/52 (50%) Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529 + W K+ + +T ++F D G +L ++ ED G+YTC A G E Sbjct: 4425 ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSE 4476 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/78 (25%), Positives = 34/78 (43%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 TG + W + K + IR + + L I DSG+Y C TN G++ Sbjct: 4979 TGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTR 5038 Query: 3135 SVKLECVDKSKGQKPRFT 3152 + +E ++K +K + T Sbjct: 5039 TFSVEIEGETKPEKGKPT 5056 Score = 34.7 bits (76), Expect = 1.9 Identities = 16/56 (28%), Positives = 24/56 (42%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 G P +V W ++EK + I H ++TI D G Y C +N G+ Sbjct: 4980 GKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGK 5035 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 3/104 (2%) Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105 +PP F KD ++ EG+ + + + + ++W +G+ ++ +T Sbjct: 2031 QPPFFQKPLKD-KEVKEGKPFKLDVKITALPEAN--VKWLKDGEPLKPGDHFKTERHGDT 2087 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKP 3149 L I D G Y C A N G+A + +G +P Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEP 2131 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Query: 2926 GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV-TLDLVDVYERDSGIY 2984 G + LE +V K P ++ W+ + K + Q SRF + G V L + V D G Y Sbjct: 2410 GDTIVLECRVTGKPRP--QVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSY 2467 Query: 2985 TCKAYNKRGEAFTSSTVYCTSKDN 3008 C A N G+ T + + + N Sbjct: 2468 KCIATNPAGQDDTVAELTVAKRGN 2491 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/95 (24%), Positives = 38/95 (40%), Gaps = 2/95 (2%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 PP+ T DL + + + + + V+WF + + + V Sbjct: 2588 PPKITQRLHDLSIDAGKTVNLTVKFFGTPEPL--VKWFMDDEEITNEDGVDIETSHCTSS 2645 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651 L + GV D G+Y C N GE + + K+ VKG Sbjct: 2646 LVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKG 2680 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 3/88 (3%) Query: 1440 VTIKPRFVTR-PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498 + + P F PK + EG + FE + + VEW K+ P++ + Sbjct: 3248 IPVPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRS 3305 Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 +L I + +DSG YTC A N G Sbjct: 3306 NDTYSLTIRGVGPDDSGAYTCTATNECG 3333 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712 ++ E V LE +V P+ ++W K+ + + + + TL INS DD Sbjct: 3657 EVTEEGDVRLEVRVGGHPKPS--VQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDI 3714 Query: 2713 GIYTCKATNLLGEAVSTASIKIE 2735 G Y A+N G A T + +E Sbjct: 3715 GQYKVIASNHRGMASRTFDVNVE 3737 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 3/85 (3%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI-TSIFNFGY 827 RP F++ D+ Q + + P V W KD +PIT + I S+++ Y Sbjct: 4498 RPTFVKD-DDMVPFQLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTY 4556 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLG 852 +L I +D G Y A N +G Sbjct: 4557 -TLIIKSPTDKDEGIYKCTASNSVG 4580 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/62 (32%), Positives = 28/62 (45%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 V+W KD +P+ +S I L IKS + D G Y C A N G S + + Sbjct: 4638 VKWSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVNRAGTNIRSFVVNVN 4697 Query: 1003 TK 1004 T+ Sbjct: 4698 TE 4699 Score = 33.9 bits (74), Expect = 3.2 Identities = 19/63 (30%), Positives = 27/63 (42%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 VEW + P+ S L I GV D+G YTC ATN G A + + ++ Sbjct: 3285 VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRTYNIDIE 3344 Query: 3651 GRQ 3653 + Sbjct: 3345 ASE 3347 Score = 33.9 bits (74), Expect = 3.2 Identities = 17/60 (28%), Positives = 26/60 (43%) Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 V+W +G+V++ RY D L IL +D G Y C N G S + ++ Sbjct: 4107 VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAGFDTRSFDIGLE 4166 Score = 33.9 bits (74), Expect = 3.2 Identities = 46/207 (22%), Positives = 79/207 (38%), Gaps = 27/207 (13%) Query: 1998 EATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNA 2057 + T+T + W + + + Q ++F T D G +L ++ ED G Y C A Sbjct: 4412 DVTMTVKTKGRPTITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETT 4471 Query: 2058 VGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTS 2117 G + ++V+ D+ I L RP ++++ P LT Sbjct: 4472 DGRSERRFDLRVE----------DDDTSTTI--LMDLVRPTFVKDDD--MVPFQLT---- 4513 Query: 2118 LENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI-RAGHRYRTTHDFGYVALDILYTYA 2176 +EGD + V P T+ W + + I H + +D Y L I Sbjct: 4514 ----EEGD---VKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTY-TLIIKSPTD 4565 Query: 2177 EDSGTYMCKATNKLGEAVNTCTLKVAG 2203 +D G Y C A+N +G + + + G Sbjct: 4566 KDEGIYKCTASNSVGTSSQMFDVDIKG 4592 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 5/74 (6%) Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLDITHTYEEDSG 2844 +EGD + V PT + W ++KP+ + S +D +Y +L I ++D G Sbjct: 4514 EEGD-VKLMVRVAGKPKPT--VTWTKDSKPITETDHIQVSVYDDTY-TLIIKSPTDKDEG 4569 Query: 2845 IYTCKATNSKGSAT 2858 IY C A+NS G+++ Sbjct: 4570 IYKCTASNSVGTSS 4583 Score = 33.9 bits (74), Expect = 3.2 Identities = 18/66 (27%), Positives = 29/66 (43%) Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728 R P +++W K+ LT + + TL I S +DD G Y C A N G + Sbjct: 4631 RGKPKPEVKWSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVNRAGTNIR 4690 Query: 2729 TASIKI 2734 + + + Sbjct: 4691 SFVVNV 4696 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 1/71 (1%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFD 4168 PP F V+EG+ + ++T P+ V WL +G + G +K G Y Sbjct: 2032 PPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLI 2091 Query: 4169 IPKTRQYDTGK 4179 IP+ D G+ Sbjct: 2092 IPEADVEDEGR 2102 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 4133 RVTGHPKPRVMWLLNGNTIVNGSRYK-LTYDGMYHFDIPKTRQYDTGKIEVI 4183 RV G PKP V W N +V S + L D ++ I K + D G +VI Sbjct: 4206 RVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVI 4257 Score = 33.1 bits (72), Expect = 5.7 Identities = 15/61 (24%), Positives = 30/61 (49%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 P+ ++W+ + + + + + +L LV V D+G+Y C +N GE T+S Sbjct: 2616 PEPLVKWFMDDEEITNEDGVDIETSHCTSSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSK 2675 Query: 3001 V 3001 + Sbjct: 2676 I 2676 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/103 (23%), Positives = 38/103 (36%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 +S+ + +RP FI + + ++ P V+W KD I +S Sbjct: 3634 DSVLDDDDERPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIISSPHF 3693 Query: 820 TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 + +L I +D G Y V A N G A T + V Sbjct: 3694 MVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNV 3736 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 2/89 (2%) Query: 1186 PPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSA 1245 P V+E ++ LE R+ G P V+W + + F L I Sbjct: 3655 PAEVTEEGDVRLEVRVG--GHPKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQD 3712 Query: 1246 DTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274 D G+Y V A NH G A + V V +D Sbjct: 3713 DIGQYKVIASNHRGMASRTFDVNVEGAND 3741 Score = 33.1 bits (72), Expect = 5.7 Identities = 17/55 (30%), Positives = 28/55 (50%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995 P +I+W+ +G+ L K+TSD T+ + +D+G Y C N G+A Sbjct: 3994 PFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGKA 4048 Score = 33.1 bits (72), Expect = 5.7 Identities = 16/55 (29%), Positives = 27/55 (49%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792 G PK V+W +N P+ S+ + + + +L ++ + D G Y A NE G Sbjct: 4209 GKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGG 4263 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/84 (22%), Positives = 35/84 (41%), Gaps = 10/84 (11%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 +P + + F GG+ K K+ G P P V+W+R + + + M +++ Sbjct: 4289 APRFLDDGISSYEFTSGGDVKLTVKVTGRPYPTVTWSRDDKDIKPDDTFHMFSDDEN--- 4345 Query: 130 SLLIKQIGPGDEGEYTCTARNQYG 153 ++G Y CT N+ G Sbjct: 4346 -------PAENQGSYKCTIANEAG 4362 Score = 33.1 bits (72), Expect = 5.7 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 2/69 (2%) Query: 660 IEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719 ++ G PT I W+K+ + I ++F G SL ++ +D G YTC A + G Sbjct: 4417 VKTKGRPT--ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGR 4474 Query: 720 AETKAVLHV 728 +E + L V Sbjct: 4475 SERRFDLRV 4483 Score = 32.7 bits (71), Expect = 7.5 Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 3/120 (2%) Query: 2233 EVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292 E+ I PP F L+ V EGK F+ V+ P +++ +G+ L+ F Sbjct: 2024 EIMMGDIQPPFFQKPLKDK-EVKEGKP--FKLDVKITALPEANVKWLKDGEPLKPGDHFK 2080 Query: 2293 ITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEK 2352 L I ED G Y +A+N G ++ + V + P+ +E+ Sbjct: 2081 TERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQ 2140 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721 L +V+ + +P + W+K+ V L R+K + + ++I +DS ++T TN Sbjct: 3764 LVLEVKIKGEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVTIKDANKEDS-VFT-NITN 3821 Query: 2722 LLGEAVSTASIKIE 2735 G A+ SI +E Sbjct: 3822 DFGTAIRRFSIDVE 3835 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 8/92 (8%) Query: 634 YPPPQFIVPL---KSVTAME---GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTS 687 Y P + + P VTA + G + R+ G P ++W KN + + SS F+ Sbjct: 4175 YEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRVR--GKPKPTVKWTKNDEPVVPSSHFSV 4232 Query: 688 IFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719 + SL + + D G Y A + G+ Sbjct: 4233 LMEDDVFSLLIRKPSKTDKGVYKVIATNEGGI 4264 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 5/72 (6%) Query: 4111 PVFVSLPDAVT---VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGMYH 4166 P FV D V EEG+ + RV G PKP V W + I +++ YD Y Sbjct: 4499 PTFVKDDDMVPFQLTEEGD-VKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTYT 4557 Query: 4167 FDIPKTRQYDTG 4178 I D G Sbjct: 4558 LIIKSPTDKDEG 4569 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 1/87 (1%) Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 V+ P +EW + + + S K+T + +L + + + D G+YT K N G Sbjct: 4871 VKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGS 4930 Query: 2995 AFTSSTVYC-TSKDNLIERTQHPKGTE 3020 + V + +L E T PK E Sbjct: 4931 GTRTFDVKVEDTTTSLFEGTVRPKFIE 4957 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 2/85 (2%) Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114 + EG FE V+ ++WY N I + + L + R E++G Sbjct: 2504 VTEGGHERFEVVVDGYPK--PEIDWYKNDILIRPGPKFDIKEHGDHHTLIVKDCRPEETG 2561 Query: 1115 VYTVVARNAAGEAQLSASMTVETRS 1139 T ARN+AG+A S + + ++ Sbjct: 2562 KLTCKARNSAGQAICSCFVQINEKT 2586 >SB_31699| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 6119 Score = 199 bits (486), Expect = 4e-50 Identities = 250/1028 (24%), Positives = 410/1028 (39%), Gaps = 141/1028 (13%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGM 3105 P F +D+ D+ EG A + + +G + +EW + + R+ M Sbjct: 3527 PHFDHPIQDL-DVIEGDRAKFHVEV--SGKPAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165 L I K TDSG Y+C A NK G+ +L K K P F + E + + Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAV--KEKMVTPSFAEGDAD-EPCEVWE 3640 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 A + V P +EW+ + + +K ++ +L I + DSG Y C+ Sbjct: 3641 GAPIKLIVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQ 3700 Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFI 3285 A N G T+ K V + + ++ P P A P F+ Sbjct: 3701 ATNDAG------TVTKTFKVVVNEQKV----------------VMRRQPIPPGAVKPSFL 3738 Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR-TFHDFGIVILDI 3344 ++QD+ ++VEG +A R+ V +P+ ++W+ + + + G R F + G+ +L I Sbjct: 3739 QRMQDL-EIVEGSAARLCVRVQGVPEPE--IDWYKDNRVIREGGRVEFEFEEDGLCMLVI 3795 Query: 3345 LYCYEENSGEYECVATNKLGRDSTKANLKCTSK--ENLILDSQLP-----RGMEGGLEKL 3397 + + G Y+CV +N G+ A L + ++ + D+ L E +E + Sbjct: 3796 RDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELI 3855 Query: 3398 QTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWY 3457 +D+ K +E+G P FT+ L N E ++EG F +R+ +KVEWY Sbjct: 3856 S--DDTSDEEKTEGAPKEEGAPPEFTLVLRNRE-VKEGGVTKFASRVI--SKAPIKVEWY 3910 Query: 3458 WNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517 + + IS +P + E+ + Y ++ + G Sbjct: 3911 KDDRL-------------------ISSDWPRHTFEH---DEDLYAMNISNVKVADGGPYT 3948 Query: 3518 IILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHF 3577 ++ ++ GT++ A Y + + PE E G P F+ + + E S+A Sbjct: 3949 FVVSNKY-----GTVESKA----YLNVLPEMEPEFE-GISPRFSVKLKNQEVIEGSTARL 3998 Query: 3578 ECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNR 3637 ECR+ V V W+ + +PL+ + + D L + V + D G Y A N Sbjct: 3999 ECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNI 4056 Query: 3638 HGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRF 3697 G + + VK P + LE K + E P P Sbjct: 4057 AGRDVCTADISVK-------HPDTDEESDIDAVDARPLESKPSKP-----KTEIPK-PEI 4103 Query: 3698 TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDI 3757 + ++D V EG V F+CR P + WF +G+P A+ R + G +L I Sbjct: 4104 VLGLRDRF-VVEGMSVRFNCRT--TSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTI 4160 Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS 3817 DAG Y C +N G A T+A +T ++EL + R S Sbjct: 4161 KDCKLADAGIYKCEVSNVGGKAGTSAHLT---------------------VEELPKSRPS 4199 Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877 +V++PP+F ++K V G + V P IEWY++ + + G R Sbjct: 4200 -------VVASPPRFQEELKG--VITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGR 4250 Query: 3878 YRTVYD----MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933 R D VSL I V D G Y C A N G DF+ AT+ K+L D ++ + Sbjct: 4251 IRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVKELDD---EDSI 4307 Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKF 3993 G T EA + T + + +PP F+ +++ Q + E ET +F Sbjct: 4308 QEGAMSLPKSTSDEALRMEDIPVAQST-----PLKRGEPPEFIRKLRDQ-FIQEKETARF 4361 Query: 3994 ECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNL 4053 C++ +G P+ EW KP+ R+T + D + ED G Y C +TN Sbjct: 4362 VCRV--IGRPDPTYEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNS 4419 Query: 4054 YGMDETKA 4061 G D T A Sbjct: 4420 SGTDTTTA 4427 Score = 181 bits (441), Expect = 1e-44 Identities = 235/924 (25%), Positives = 362/924 (39%), Gaps = 130/924 (14%) Query: 1308 MQAPQFSR--ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365 M P F+ A E EG + L +++ G VEWF + K + E Sbjct: 3622 MVTPSFAEGDADEPCEVWEGAPIKLIVQIK--GKPAPTVEWFKEKRQAKRLKNVKLFTEG 3679 Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425 D L + PEDSG Y CQATN G + + V +K ++ P G K Sbjct: 3680 DKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVNEQKVVMRRQPIPPGAVK----- 3734 Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485 P F+ R + +E ++EG +++ V + +++W+K+ + Sbjct: 3735 ------------------PSFLQRMQDLE-IVEGSAARLCVRVQGVPEP--EIDWYKDNR 3773 Query: 1486 PVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR------- 1537 + G R + G L I D D G Y C N G + S L Sbjct: 3774 VIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSG 3833 Query: 1538 -STTDIVRSTQNEAGLEQIQVL-EDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRA 1595 S D+ + + EA I+++ +D S +T+ + P T L+N E+KEG Sbjct: 3834 VSDADLDFAARKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVT 3893 Query: 1596 HFERRLIPVSDATLKVEWYHNNKPLKSG-SRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654 F R+I S A +KVEWY +++ + S R T ++ A++I + D G YT Sbjct: 3894 KFASRVI--SKAPIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVV 3951 Query: 1655 INALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFT 1714 N G + V + +E + EG PR F+ Sbjct: 3952 SNKYGTVESKAYLNVLPE----MEPEFEGISPR-------------------------FS 3982 Query: 1715 MPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKY 1774 + +K+ V E A E R+ VG P V W R+ P+ S + D + AL +K Sbjct: 3983 VKLKNQEVIEGSTARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKD 4040 Query: 1775 VNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRRE 1834 V+ ED G Y A N G V ++ + V+ + + ES ++ + + + S Sbjct: 4041 VSEEDDGHYKAVARNIAGRDVCTADISVKHPDTDE-ESDIDAVDARPLESKPSKPKTEIP 4099 Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894 E+ + RF+ EG S + CR P P V W+ +G+ L S RY Sbjct: 4100 KPEIVLGLRDRFVV---------EGMSVRFNCRTTSQPKP--YVTWFKDGQPLASYGRYE 4148 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954 ++ G +L I D+G Y C+ N G+A +S L V+ E + Sbjct: 4149 VTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVE-----------ELPKSR 4197 Query: 1955 IQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWY 2014 + R++ ++ VV G K + GHP TPV +EWY Sbjct: 4198 PSVVASPPRFQEELKGVITVV-----GTTTKLSVPIIGHP-------TPV------IEWY 4239 Query: 2015 CNGRPVQQGHRFKTTYD----FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 + R V +G R + D F V+L I D G Y C A N G ++++VKV Sbjct: 4240 KDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVK 4299 Query: 2071 AKSGLYLDTLDEQRL---KKIQELEKYERPKPIEEEQP---GQRPVFLTALTSLENLKEG 2124 D++ E + K + P+ + P G+ P F+ L + ++E Sbjct: 4300 ELDD--EDSIQEGAMSLPKSTSDEALRMEDIPVAQSTPLKRGEPPEFIRKLRD-QFIQEK 4356 Query: 2125 DRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMC 2184 + A F CRV I P T +W + I G RY D L+I ED G Y C Sbjct: 4357 ETARFVCRV--IGRPDPTYEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKC 4414 Query: 2185 KATNKLGEAVNTCTLKVAGHRNII 2208 +TN G T L V R I Sbjct: 4415 VSTNSSGTDTTTARLTVEASRRPI 4438 Score = 178 bits (434), Expect = 8e-44 Identities = 181/713 (25%), Positives = 279/713 (39%), Gaps = 45/713 (6%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFD-- 4168 P F S V EEG+ RF V G PKP V+W I R+++ H Sbjct: 104 PSFTSKMKPVDAEEGQEVRFDVHVKGSPKPDVVWYKGSTMIGTHERFQIVEAAEDHVTLV 163 Query: 4169 IPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTE 4228 I + + D +V+ L+V R + + R D TT + T Sbjct: 164 ISEVKLEDAETYKVVATNDVGKVTSRADLRVKERQ--FAPEFIDEERGPIDATTGDEVTL 221 Query: 4229 TELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQ 4288 T + + + LK + E W + K + K E EN+ Sbjct: 222 TCSVSGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKC-EAENK- 279 Query: 4289 VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTE-EVTEQRVQKKVTQKPRI 4347 + K SR + + P S T+ + + E + +VT + K + Sbjct: 280 LGKASRAFDV--KVKAPKGDAPSFTIDLTHVRAIEGEESKLVCKVTGKPAPTIEWLKGEL 337 Query: 4348 PDPSESTVHG---KEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGP 4404 P + V K V K T+ G ++ + S I + Q QER Sbjct: 338 PVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIA-ELQVQER----- 391 Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464 S P ++ E+ +F+V G+P P ++W + I++ F I S Sbjct: 392 ---STKPEIEDSLRDVSALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERFTIAEESD 448 Query: 4465 KSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523 + LII+ + D+ + VA N G A+ A L V E+ ++ P F ++ Sbjct: 449 EVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEE-------LIGPRFEKMKESF 501 Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583 V G+ V L +VTG ++ W K+GK V+ E D L I E+ DSG Sbjct: 502 TVVEGESVELVARVTGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGL 561 Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643 Y C A N +G A + L KPK PEI+ L+ EG S Sbjct: 562 YRCTARNKSGTA----DMTFQLDVQPKKPK------GTAPEIVSELRPVEATEGDDAVLS 611 Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 C I GKP+PT++W K +K S+ + E L I +D+GDY C+ N G Sbjct: 612 CTISGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGS 671 Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763 KLKV + + L P++ + EG+ Q ++ KP I+W R +I E Sbjct: 672 AESKTKLKVIAFARPEFRTKLKPVKAV---EGEEVQLDVKVEGYPKPDIEWYRGTTMIVE 728 Query: 4764 TPDFQMIHEGNN---AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + F+++ E L+I +DTGT AT A+G+ + A L VK + Sbjct: 729 SGRFKVMEEEEEDGLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKER 781 Score = 177 bits (431), Expect = 2e-43 Identities = 120/408 (29%), Positives = 185/408 (45%), Gaps = 25/408 (6%) Query: 4410 PPIFTKKMQ-PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 P I T ++ P + E + R V G P+P ++WY++ I+ S + + ++ L Sbjct: 3333 PEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSL 3392 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528 I V ED+ V VA N G+A S +V+E K+ P F + V G Sbjct: 3393 AIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKKPA-------PLFIAPLHDQEVVEG 3445 Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY-TLLILEAYPQDSGKYECV 4587 + +RL+ +V T V W K+G+ + D + E DG + TL+I A +D G YEC+ Sbjct: 3446 ETIRLECRVRATPRPMVEWKKDGRTFKEDY-HIYTEFDGQHCTLVIKGAQIEDEGAYECI 3504 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647 A N G R A+ V K A P P++D V EG +F ++ Sbjct: 3505 AKNKEGRGRSVAQLTV-------------KEALIIPHFDHPIQDLDVIEGDRAKFHVEVS 3551 Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMS--RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705 GKP V+W KGD+ ++ + R Y L I+ P D G Y C+A N AG T Sbjct: 3552 GKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSGKYTCIARNKAGENT 3611 Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765 +L V + + V+EG P + QI K PT++W +E Sbjct: 3612 CHGRLAVKEKMVTPSFAEGDADEPCEVWEGAPIKLIVQIKGKPAPTVEWFKEKRQAKRLK 3671 Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + ++ EG+ +L+I ED+G + C+AT AG V + K+VV + Sbjct: 3672 NVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVNEQ 3719 Score = 177 bits (430), Expect = 2e-43 Identities = 111/418 (26%), Positives = 201/418 (48%), Gaps = 18/418 (4%) Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 V+GP + PI K++P E E+ + + F G+P P +W R+ I++S QI Sbjct: 877 VKGP--KGEAPIILSKLRPVETEEGEETKLKCTFTGKPAPTCEWTRDGIRIRSSRMVQID 934 Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520 T S LII++ ++D ++ +N GT SA ++V E + G G ++ Sbjct: 935 TTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNEVEK-GVGPVIEEKL---- 989 Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYP 4578 ++V V G+ +V+G +D W K+ + + R I+E ++G ++L I + P Sbjct: 990 KDVTVMPGEEAEFSIRVSGRAEVD--WFKDEVMLNDEGRF-IMEGGDNGRFSLTISDVRP 1046 Query: 4579 QDSGKYECVAINSAGEARCDAECVV--SLPATKDKPKPQT-KAANAPPEIIEPLKDKIVA 4635 +D G Y+C+ N +G+ A+ + ++ A ++ +T + P+I +PL+ V Sbjct: 1047 EDKGTYKCLVFNESGKVTTRAKLCIKEAIVAPEEVDAAETVPIEGSAPKITKPLESVEVN 1106 Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695 EG+ + C + G P PTV+W K ++ S + + L +A PED G+YKC Sbjct: 1107 EGEDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKC 1166 Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755 N G+ + ++KV + + ++P + V EG A F+ ++ K ++W Sbjct: 1167 TVINEHGKASTTGEVKVNVLSRPEFKIKMSP---VEVTEGSEAAFEVRVEGFPKLQVEWF 1223 Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + I ++ + + N ++I N ED G + C AT AG+ + A L VK + Sbjct: 1224 KGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKER 1281 Score = 173 bits (420), Expect = 4e-42 Identities = 176/735 (23%), Positives = 295/735 (40%), Gaps = 66/735 (8%) Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155 V P++ ++ +A P V A V EG + CRVTG P P + W + + Sbjct: 2834 VKPKRGLKPGEAA--PEIVQRLKACEVPEGSSFKLRCRVTGTPTPTIEWYKSNMPLKPNG 2891 Query: 4156 RYKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHD--DYRGVLKN 4212 R + + G Y + +T D G+ ++ L + P +R L Sbjct: 2892 RVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVSPPSFRHRLTA 2951 Query: 4213 APRPWYDET---TQYQRTETELEKTFEERQVLQRQG---VIDHRPELKPKVI----KEPE 4262 DET + ++ T +E ++E+Q + G VI+ E ++ K + Sbjct: 2952 VEVDEGDETRFDVRLKKEPTSVE-WYKEQQRIFTDGHFEVIEGEEECLYSLVISNTKVAD 3010 Query: 4263 TEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIP-GDKVTSNTVAKSMAQR 4321 + ++ + + + L NE++I Y + GD +T + V K Sbjct: 3011 AGGYKCTALNESGKSSTRAELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVKG--NP 3068 Query: 4322 YEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRK 4381 Y + +E KK+ R S + H K K VG Sbjct: 3069 YPEIRWYKDEFLAME-SKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVG------- 3120 Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441 T+T++ ++ +A+ + ++ P F ++++ + ARFE + G P P Sbjct: 3121 -TATKSFTVDVEAKKSKGII---------PEFFRQLRRVEAVQGSTARFECKVSGHPEPQ 3170 Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLV 4499 I W ++ + P + I F + L + ED + VA N G A A+LV Sbjct: 3171 IAWLKDGKELA-IPRY-IKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASLV 3228 Query: 4500 VEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIR 4559 + + +V P F +N+ V G + +V G V W K GKK++ R Sbjct: 3229 LSKP-------LVMPEFKERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKKIKSHAR 3281 Query: 4560 -NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKA 4618 + E TYTL I + +D G Y+CVA N AG+ +C V K Sbjct: 3282 FSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV-------------KE 3328 Query: 4619 ANAPPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676 PPEI + + ++ EG + + G P+P +QWYK LI+ S + +S Sbjct: 3329 RMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGS 3388 Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736 Y+L I PED G KCVA N AG + + + + A + PL D V EG+ Sbjct: 3389 RYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKKPAPLF--IAPLHDQEVVEGE 3446 Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796 + + ++ + +P ++W ++G E +G + L+I ED G + C A Sbjct: 3447 TIRLECRVRATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCTLVIKGAQIEDEGAYECIAK 3506 Query: 4797 TAAGQVETSAKLVVK 4811 G+ + A+L VK Sbjct: 3507 NKEGRGRSVAQLTVK 3521 Score = 168 bits (409), Expect = 8e-41 Identities = 121/464 (26%), Positives = 214/464 (46%), Gaps = 32/464 (6%) Query: 4360 VHVAKQKQTQKEVV-GDKEITRKITSTE-----TTEIEHKAQTQERVVEGPVKPSKPPIF 4413 + V ++T+ ++V G+ ++T K T + T + ++ + E + V P F Sbjct: 629 IRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIAFARPEF 688 Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS---ILII 4470 K++P + E E+ + +V+ +G P P I+WYR I S F++ + L+I Sbjct: 689 RTKLKPVKAVEGEEVQLDVKVEGYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGLYSLVI 748 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTSGQ 4529 ++ ++D+ VA N G A A+L V+E+ P F + + VT G Sbjct: 749 SKLQLDDTGTIKVVATNASGKATSRADLEVKERE-------FAPEFEGDEEGPIVVTEGN 801 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589 V + +V DV W K+G+ + + I +TL I + +D+G Y+C A Sbjct: 802 EVSIQLRVKANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEAS 861 Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649 N G+A + V + K + P I+ L+ EG+ + C GK Sbjct: 862 NRLGKASRSFDVKVQVKGPKGEA----------PIILSKLRPVETEEGEETKLKCTFTGK 911 Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709 P PT +W + I+ S+ Q+ T D TL I E +DEG YKC N G V+ +A+ Sbjct: 912 PAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAE 971 Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769 + V + ++ L+D+ V G+ A+F +++ + + + W ++ ++ + F + Sbjct: 972 VLVNEVEKGVGPVIEEKLKDVTVMPGEEAEFSIRVSGRAE--VDWFKDEVMLNDEGRF-I 1028 Query: 4770 IHEGNNA--VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 + G+N L I + ED GT+ C +G+V T AKL +K Sbjct: 1029 MEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIK 1072 Score = 168 bits (408), Expect = 1e-40 Identities = 166/691 (24%), Positives = 281/691 (40%), Gaps = 61/691 (8%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P F+ ++ +G AKF ++ G P V W + L + S+ + +T L Sbjct: 3527 PHFDHPIQDLDVIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFL 3586 Query: 132 LIKQIGPGDEGEYTCTARNQYGE-------AICSVYIQP---EGXXXXXXXXXXXXXYRH 181 I P D G+YTC ARN+ GE A+ + P EG + Sbjct: 3587 TITNCKPTDSGKYTCIARNKAGENTCHGRLAVKEKMVTPSFAEGDADEPCEVWEGAPIKL 3646 Query: 182 VSETVEHKAYGTQGYTTE-QSRQTQKVA-YTNGTDHSST--DDFKVDTFEYRLLREVSFR 237 + + A + + + Q+++ + V +T G H D+ YR + + Sbjct: 3647 IVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRC-QATNDA 3705 Query: 238 ESITKRYVGESDVQISTEIDRSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPR 296 ++TK + + Q + + P + P Q+ ++ ++ EG+ A+ V++ G P P Sbjct: 3706 GTVTKTFKVVVNEQKVVMRRQPIPPGAVKPSFLQRMQDLEIVEGSAARLCVRVQGVPEPE 3765 Query: 297 VTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 + W+K+ + + + E L +R+ KSD G Y + N G S L + Sbjct: 3766 IDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFI 3825 Query: 356 ESPT-ESYVQDQRSQYITDTQQRET-----------EERIEIS--EKALAPQFVKVCQDR 401 E+ +S V D + + RE+ EE+ E + E+ P+F V ++R Sbjct: 3826 ETHGFDSGVSDADLDFAARKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNR 3885 Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461 +V EG +T+F RV + +V W+ +DR I D+ ++ +A+ I+NV ++D G Sbjct: 3886 EVKEGGVTKFASRVISKAPIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGG 3945 Query: 462 VVTCVARNKSGETAFQCRLNVI-EKE---QVVAPKFVERFSTLNVREGEPVVLNARAVGT 517 T V NK G + LNV+ E E + ++P+F + V EG L R VG+ Sbjct: 3946 PYTFVVSNKYGTVESKAYLNVLPEMEPEFEGISPRFSVKLKNQEVIEGSTARLECRIVGS 4005 Query: 518 PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577 P P + W +D P+I + + ++ DG L + D Y+ A+N+AG A Sbjct: 4006 PVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTAD 4065 Query: 578 LYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPP 637 + K + + E +P I G DR Sbjct: 4066 I----------SVKHPDTDEESDIDAVDARPLESKPSKPKTEIPKPEIVLGLRDR----- 4110 Query: 638 QFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLD 697 F+V EG + F R P + W K+GQ + + R+ G SL Sbjct: 4111 -FVV--------EGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLT 4159 Query: 698 MLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + + D+G Y C + G A T A L V Sbjct: 4160 IKDCKLADAGIYKCEVSNVGGKAGTSAHLTV 4190 Score = 167 bits (407), Expect = 1e-40 Identities = 122/424 (28%), Positives = 199/424 (46%), Gaps = 36/424 (8%) Query: 4405 VKPSKP-PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT-F 4462 ++ KP P+F + V E E R E P P+++W ++ K D+ I+T F Sbjct: 3424 IESKKPAPLFIAPLHDQEVVEGETIRLECRVRATPRPMVEWKKDGRTFKE--DYHIYTEF 3481 Query: 4463 STKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521 + L+I+ +ED + +A+N+ G + A L V+E ++ P F Q Sbjct: 3482 DGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKE-------ALIIPHFDHPIQ 3534 Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT--YTLLILEAYPQ 4579 +++V G + +V+G V WLK ++++ R + E+ T Y L I P Sbjct: 3535 DLDVIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPT 3594 Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 DSGKY C+A N AGE C V K K T + A + EP + V EG Sbjct: 3595 DSGKYTCIARNKAGENTCHGRLAV-------KEKMVTPSF-AEGDADEPCE---VWEGAP 3643 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 I+ +I GKP PTV+W+K + K K ++ D++ L I +A PED G+Y+C A N Sbjct: 3644 IKLIVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATN 3703 Query: 4700 SAGRVTVAAKLKVTQ----------PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749 AG VT K+ V + P A L ++D+ + EG A+ ++ + Sbjct: 3704 DAGTVTKTFKVVVNEQKVVMRRQPIPPGAVKPSFLQRMQDLEIVEGSAARLCVRVQGVPE 3763 Query: 4750 PTIQWLREGALIPETPDFQM-IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 P I W ++ +I E + E +L+I + + D G + C + AAG+ + SA+L Sbjct: 3764 PEIDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAEL 3823 Query: 4809 VVKS 4812 +++ Sbjct: 3824 FIET 3827 Score = 167 bits (406), Expect = 2e-40 Identities = 169/725 (23%), Positives = 300/725 (41%), Gaps = 57/725 (7%) Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161 V+ K P + L +E GE ++ C+VTG P P + WL + R + + Sbjct: 291 VKAPKGDAPSFTIDLTHVRAIE-GEESKLVCKVTGKPAPTIEWLKGELPVTTSLRVRTDF 349 Query: 4162 D-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDE 4220 + + I TR D G +V+ L+V R + +P ++ Sbjct: 350 EKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQER----------STKPEIED 399 Query: 4221 TTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNK 4280 + + F+ R + + ++ R VI++ E + ++ + +E + Sbjct: 400 SLRDVSALPGERVKFKVRIGGKPKPKVEWRK--GKSVIEDGE---RFTIAEESDEVFSLI 454 Query: 4281 LQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSM-AQRYEDNLDQTEEVTEQRVQ- 4338 +Q+LE R + A + + TV + + R+E + V + V+ Sbjct: 455 IQDLEETDA---GRYKCVATNEAGEAESMAQLTVNEELIGPRFEKMKESFTVVEGESVEL 511 Query: 4339 -KKVTQKPRIPDPSESTVHGKEV----HVAKQKQTQKEVVGDKEITRKITSTETTEIEHK 4393 +VT KP P+ E T GK V +V +++ + V+ +E +R + +K Sbjct: 512 VARVTGKP-APE-IEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNK 569 Query: 4394 AQTQERVVEGPVKPSKP----PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449 + T + + V+P KP P +++P E + A G+P+P I+W + Sbjct: 570 SGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAVLSCTISGKPVPTIEWLKNGI 629 Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509 +K+S + + L I+ +D + + N G+A+ L V R Sbjct: 630 RVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIAFAR---- 685 Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL---EED 4566 P F + V G+ V+LD KV G D+ W + + R K++ EED Sbjct: 686 ----PEFRTKLKPVKAVEGEEVQLDVKVEGYPKPDIEWYRGTTMIVESGRFKVMEEEEED 741 Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626 G Y+L+I + D+G + VA N++G+A A+ L + + P+ + P Sbjct: 742 GLYSLVISKLQLDDTGTIKVVATNASGKATSRAD----LEVKEREFAPEFEGDEEGP--- 794 Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686 +V EG + ++ P V W+K + I S + R +E+TL I + Sbjct: 795 -----IVVTEGNEVSIQLRVKANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSS 849 Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP-ALTPLRDIVVYEGQPAQFKTQIT 4745 ED G YKC A N G+ + + +KV P L+ LR + EG+ + K T Sbjct: 850 LEDTGVYKCEASNRLGKASRSFDVKVQVKGPKGEAPIILSKLRPVETEEGEETKLKCTFT 909 Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805 K PT +W R+G I + Q+ +++ L+I T +D G + C G V TS Sbjct: 910 GKPAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTS 969 Query: 4806 AKLVV 4810 A+++V Sbjct: 970 AEVLV 974 Score = 167 bits (406), Expect = 2e-40 Identities = 127/474 (26%), Positives = 213/474 (44%), Gaps = 32/474 (6%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+ + K +N ++ EG+ A+ + ++ G+P P V W+++ + LI S K+++ +H L V Sbjct: 3979 PRFSVKLKNQEVIEGSTARLECRIVGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIV 4038 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 ++ + D GHY +A N G V + ++V+ P D + + + ++ + EI Sbjct: 4039 KDVSEEDDGHYKAVARNIAGRDVCTADISVKHPDTDEESDIDAVDARPLESKPSKPKTEI 4098 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 + P+ V +DR V EG RF+CR T +P P VTWF D Q Y + + + Sbjct: 4099 PK----PEIVLGLRDRFVVEGMSVRFNCRTTSQPKPYVTWF-KDGQPLASYGRYEVTSVA 4153 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE----KEQVVA--PKFVERFST 499 G +L I + L+D+G+ C N G+ L V E + VVA P+F E Sbjct: 4154 GAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPSVVASPPRFQEELKG 4213 Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGAST---LDIPRAKA 555 + G L+ +G PTP I W KD ++ +R D G T L I + Sbjct: 4214 VITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRL 4273 Query: 556 SDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQK-RLHLPRPTKVXXXXXXXXXXXXY 614 +D Y+C A+N +G+ + A + Q+ + LP+ T Sbjct: 4274 TDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDI----- 4328 Query: 615 LRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLK 674 V ++ P + GE PP+FI L+ E F R+ +G P EWL+ Sbjct: 4329 --PVAQSTP-LKRGE------PPEFIRKLRDQFIQEKETARFVCRV--IGRPDPTYEWLR 4377 Query: 675 NGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + I R+T + +L++ ++D G Y C + +++G T A L V Sbjct: 4378 GDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTV 4431 Score = 163 bits (397), Expect = 2e-39 Identities = 118/409 (28%), Positives = 180/409 (44%), Gaps = 26/409 (6%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSIL 4468 PIF +K++ E E RFEV+ P P ++W++ + I + F I S +L Sbjct: 1470 PIFQQKLKAVSTIEGESTRFEVKLSAMPRPTVEWFKSSSQIYDGGRFTITEEENSGVYVL 1529 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTS 4527 +I +ED+ + VA N G A L V E + P F A+ + T Sbjct: 1530 VIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEV-------LTVPEFMDKAEGPIEKTE 1582 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 G + L +V G ++ W K + + R D +T+ + + DSG Y+CV Sbjct: 1583 GDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCV 1642 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647 A N AG S T + + K P+II L K V EG + C + Sbjct: 1643 ARNKAG----------SSSRTFNLDVQKKKVIGNAPDIITHLISKEVKEGGTVTLECTVS 1692 Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707 GKP P ++WYK ++ + ++ ++A D+G+YKCVA N G + Sbjct: 1693 GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSS 1752 Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767 A+L VT P + + L PL V EG A+F +I S KP ++W R I ++ Sbjct: 1753 ARLTVTVPSKPEFKQKLRPLE---VVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRH 1809 Query: 4768 QMI--HEGNNAV-LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 Q+ +EG++ L+I NT ED + C A AG+ A L V K Sbjct: 1810 QITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK 1858 Score = 161 bits (392), Expect = 1e-38 Identities = 108/382 (28%), Positives = 168/382 (43%), Gaps = 20/382 (5%) Query: 4432 VEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491 +E G P P I+WY I + Q+ S+K+ + + V ++DS ++ A N GT Sbjct: 2179 LEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGT 2238 Query: 4492 AKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551 N+ V+ KR +G P+ ++V V G+ L+ V+GT + W ++G Sbjct: 2239 GSKQFNINVQPKRPEG----TEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDG 2294 Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611 +V+ R + E+G L+I E + +D G Y+C N G A + + AT+ Sbjct: 2295 LRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI-IVATR-- 2351 Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671 PE E L V EG +F ++ G P P V+WY G I F++ Sbjct: 2352 -----------PEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEI 2400 Query: 4672 SRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729 + Y+L + E ED G YKC+A N AG+ T A L+V + A Sbjct: 2401 ESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQFAPEFETGEERGP 2460 Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789 IVV EG K + + KP + W ++G E + GN L I N ED+G Sbjct: 2461 IVVPEGGETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSG 2520 Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811 ++ C A G + S + V+ Sbjct: 2521 SYKCEARNKLGFADKSFTIRVE 2542 Score = 161 bits (392), Expect = 1e-38 Identities = 115/414 (27%), Positives = 179/414 (43%), Gaps = 25/414 (6%) Query: 4405 VKPS-KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463 ++PS PP F ++ V E ++ RF+V EP ++WY+E I F++ Sbjct: 2936 IEPSVSPPSFRHRLTAVEVDEGDETRFDVRLKKEPTS-VEWYKEQQRIFTDGHFEVIEGE 2994 Query: 4464 TKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521 + + L+I V D+ + A N G + A L+V E+ ++PP F Sbjct: 2995 EECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER-------LIPPGFEGPDH 3047 Query: 4522 -NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580 + + G + LD V G ++ W K+ + + D +L + P+D Sbjct: 3048 GSYELQEGDTITLDAVVKGNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKD 3107 Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640 SG Y+CV N G A V + A K K PE L+ +G Sbjct: 3108 SGVYKCVLKNKVGTAT--KSFTVDVEAKKSK--------GIIPEFFRQLRRVEAVQGSTA 3157 Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700 F CK+ G P P + W K K + +Y + + L E PEDEGDY CVA N Sbjct: 3158 RFECKVSGHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDEGDYTCVASNE 3217 Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760 AG + A L +++P L++I V EG AQF ++ + +P ++W + G Sbjct: 3218 AGEASSHASLVLSKPLVMPEFK--ERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKK 3275 Query: 4761 IPETPDF-QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 I F E + L I + ED GT+ C A+ AG+V+ S +L VK + Sbjct: 3276 IKSHARFSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329 Score = 161 bits (390), Expect = 2e-38 Identities = 211/876 (24%), Positives = 338/876 (38%), Gaps = 129/876 (14%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P VEW + + + + L + PEDSG Y C+A N+ G + Sbjct: 3652 GKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKT 3711 Query: 1798 STLFV-QSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856 + V + K ++ + A++ S QR +D+E+ Sbjct: 3712 FKVVVNEQKVVMRRQPIPPGAVKP-------SFLQRMQDLEIV----------------- 3747 Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS-NDFGFAALDILTVYGEDSG 1915 EG +A R++ P+P ++WY + +V++ G R + G L I D G Sbjct: 3748 -EGSAARLCVRVQGVPEPE--IDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRG 3804 Query: 1916 EYTCKAINNLGQAVSSIRLNVQSK--ESIIRDSQHESALEK------IQYLEDDSRYKRA 1967 Y C N G+A S L +++ +S + D+ + A K I+ + DD+ + Sbjct: 3805 RYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELISDDTSDEEK 3864 Query: 1968 VQD-DSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HR 2025 + P+F ++N EV EG + + ++ ++VEWY + R + R Sbjct: 3865 TEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRV--ISKAPIKVEWYKDDRLISSDWPR 3922 Query: 2026 FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL 2085 +D A++I D G Y +N G V++K+ YL+ L E Sbjct: 3923 HTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYG--------TVESKA--YLNVLPE--- 3969 Query: 2086 KKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW 2145 +E E G P F L + E + EG A ECR+ + P + W Sbjct: 3970 --------------MEPEFEGISPRFSVKLKNQEVI-EGSTARLECRI--VGSPVPEVRW 4012 Query: 2146 FHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR 2205 + + + + +Y+ D + AL + ED G Y A N G V T + V H Sbjct: 4013 YRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVK-HP 4071 Query: 2206 NIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQ 2265 DT + ++ + + ++ + E PK P V LR V EG + F C+ Sbjct: 4072 ----DTDEESDIDAVDARPLESKPSKPKTEIPK---PEIVLGLR-DRFVVEGMSVRFNCR 4123 Query: 2266 VEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH 2325 P + ++ +G+ L S R+ +T G SL I+ C DAG Y + N G Sbjct: 4124 T--TSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGK 4181 Query: 2326 CTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNI 2385 ++ +TV E L K R A P P F + L+ + Sbjct: 4182 AGTSAHLTV-------------EELPKSRPSVVASP--------------PRFQEELKGV 4214 Query: 2386 DNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD----FGYVSMTISHV 2441 + G T +I G PT +EW+++++ + + RI D F VS+TI V Sbjct: 4215 ITV-VGTTTKLSVPII--GHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDV 4271 Query: 2442 RDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE- 2500 R DEG Y C A N G + E EG + K R E+ Sbjct: 4272 RLTDEGRYKCVAKNKSG---TDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDI 4328 Query: 2501 ------PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554 P + E P F + L + E + A + RV +G P +EW + G Sbjct: 4329 PVAQSTPLKRGEPPEFIRKLR-DQFIQEKETARFVCRV--IGRPDPTYEWLRGDKPITDG 4385 Query: 2555 SRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 R+ D TL+I D GLY C + N +G Sbjct: 4386 GRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSG 4421 Score = 160 bits (389), Expect = 2e-38 Identities = 118/409 (28%), Positives = 188/409 (45%), Gaps = 25/409 (6%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-LI 4469 P +K+Q E+A F++ G P+P+++WYR + I + + L Sbjct: 2647 PRILEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLT 2706 Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSG 4528 I + ED + AV N G +A L + E G++ PSF + + + G Sbjct: 2707 IEYIDYEDEGAYKAVVINDSGEVSSTAVLRLAE-------GMIEPSFIGIEFEPITAYEG 2759 Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588 + L V G V +LK+ V R ++ +TL + + +DS Y+ VA Sbjct: 2760 SDIDLTFYVKGRPLPTVEFLKDEVPVFKSDRTELTSNGNRHTLYLSDLAVRDSATYKAVA 2819 Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648 N AG AR E +V KPK K A PEI++ LK V EG + + C++ G Sbjct: 2820 KNKAGVARRSVELLV-------KPKRGLKPGEAAPEIVQRLKACEVPEGSSFKLRCRVTG 2872 Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708 P PT++WYK + +KP+ + T D+Y L E DEG Y VA N G V+ +A Sbjct: 2873 TPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSA 2932 Query: 4709 KLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPT-IQWLREGALIPETPD 4766 +L + +P + P+ L + V EG +F ++ K +PT ++W +E I Sbjct: 2933 EL-IIEPSVSP--PSFRHRLTAVEVDEGDETRFDVRL--KKEPTSVEWYKEQQRIFTDGH 2987 Query: 4767 FQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 F++I + L+I NT D G + C A +G+ T A+L+V + Sbjct: 2988 FEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036 Score = 159 bits (387), Expect = 4e-38 Identities = 192/779 (24%), Positives = 317/779 (40%), Gaps = 96/779 (12%) Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSC 1642 ++++EI EG A R+ V + +++WY +N+ ++ G R E G L I Sbjct: 3741 MQDLEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDA 3798 Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVH--------SKKSIYLESQHEGALPRLNQL-ED 1693 D G Y C NA G+A S + S + ++ E + + +D Sbjct: 3799 TKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELISDD 3858 Query: 1694 TSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753 TS ++ + P FT+ +++ V E F +R+I ++VEW ++ I Sbjct: 3859 TSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVI--SKAPIKVEWYKDDRLI 3916 Query: 1754 EAS-NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812 + R T HD A+N+ V D G YT N+ G V+SKA L + Sbjct: 3917 SSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGT--------VESKAYLNVLP 3968 Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872 + E + I +PRF +L ++ EG +A ECRI P Sbjct: 3969 EMEPEFEGI---------------------SPRFSVKLKNQ-EVIEGSTARLECRIVGSP 4006 Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932 P +R WY + + L +Y+ D AL + V ED G Y A N G+ V + Sbjct: 4007 VPEVR--WYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTA 4064 Query: 1933 RLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEG 1992 ++V+ D+ ES ++ + +S+ + + + KP+ +++ V EG Sbjct: 4065 DISVKHP-----DTDEESDIDAVDARPLESKPSKPKTE----IPKPEIVLGLRDRFVVEG 4115 Query: 1993 HPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMC 2052 V T + P V W+ +G+P+ R++ T G +L I D G Y C Sbjct: 4116 MSVRFNCRTT--SQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKC 4173 Query: 2053 KATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFL 2112 + +N G+A T++ + V + L + R + P +EE G + Sbjct: 4174 EVSNVGGKAGTSAHLTV--------EELPKSRPSVVAS------PPRFQEELKG----VI 4215 Query: 2113 TALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD----FGYVA 2168 T + + L V I P I+W+ + +++ G R R D F V+ Sbjct: 4216 TVVGTTTKLS----------VPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVS 4265 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA-QG 2227 L I D G Y C A NK G ++ T+KV + + L K EA + Sbjct: 4266 LTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRM 4325 Query: 2228 HSTRIEVEEP--KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285 + P + PP F+ +LR + E +TA F C+V + P+ E+ K + Sbjct: 4326 EDIPVAQSTPLKRGEPPEFIRKLR-DQFIQEKETARFVCRV--IGRPDPTYEWLRGDKPI 4382 Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344 R+ I D +L+I C ED G Y + N+ G T+ +TV A IS++ Sbjct: 4383 TDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPISKN 4441 Score = 159 bits (387), Expect = 4e-38 Identities = 239/1076 (22%), Positives = 407/1076 (37%), Gaps = 153/1076 (14%) Query: 3820 PKEEP-IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878 P+ EP P+F ++K+ V E R ECR+ P++R WYR+ + L +Y Sbjct: 3968 PEMEPEFEGISPRFSVKLKNQEVIEGSTARLECRIVGSPVPEVR--WYRDNEPLIESEKY 4025 Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938 + D +L + V ED G Y A N G D A IS K PD ++ + Sbjct: 4026 QMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKH-PDTDEESDIDAVDA 4084 Query: 3939 RSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLA 3998 R +E+ K +E+ P V ++ + +VE + +F C+ Sbjct: 4085 RP-----LESKPSKPKTEI-------------PKPEIVLGLRDRF-VVEGMSVRFNCRTT 4125 Query: 3999 PVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDE 4058 P V WF +G+PL R+ G ++ D+G Y C +N+ G Sbjct: 4126 --SQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAG 4183 Query: 4059 TKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPD 4118 T A + +LPK S+ +P + EE K Sbjct: 4184 TSAHLTV---------EELPKSRPSVV----------ASPPRFQEELKG----------- 4213 Query: 4119 AVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPK-----TR 4173 +TV G + + GHP P + W + ++ G R + D F I R Sbjct: 4214 VITVV-GTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVR 4272 Query: 4174 QYDTGKIEVIXXXXXXXXXXXXXLKV--IPRHDDYRGVLKNAPRPWYDETTQYQR---TE 4228 D G+ + + +KV + D + + P+ DE + + + Sbjct: 4273 LTDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDIPVAQ 4332 Query: 4229 TELEKTFEERQVLQ--RQGVIDHRPELK--PKVIKEPET--EWQQSVKRKKNEEYYNKLQ 4282 + K E + ++ R I + + +VI P+ EW + K + Y + Sbjct: 4333 STPLKRGEPPEFIRKLRDQFIQEKETARFVCRVIGRPDPTYEWLRGDKPITDGGRYTIMS 4392 Query: 4283 ELENEQV-IKESRLR-ESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKK 4340 + E + + I + + E ++ T T A+ ++ + + ++K Sbjct: 4393 DDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARL-------TVEASRRPISKNIEKL 4445 Query: 4341 VTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTE-IEHKA---QT 4396 + + + + S S +AK E++G+ E K E +E +A +T Sbjct: 4446 LIKAASMDEESMSQA------LAKAIAESPELLGEPEPESKPADEPAKEPVEEEALLPET 4499 Query: 4397 QERVVEGPVKP---SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453 R + P +P S P+F +K + CR+ E + ARF V+ +G P P + W+ I+ Sbjct: 4500 ASRADQTPDEPTAESGEPVFVQKPETCRLKEGDTARFNVKVNGSPEPFVDWFLGRRMIEE 4559 Query: 4454 SPDFQIHTFST-KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV--EEKRRQGRGG 4510 +I + L+I + ED+ V+ VAEN G+ C A L+V EE Sbjct: 4560 DDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPT 4619 Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL-----KNGKKVQPDIR------ 4559 V P+ T KP+ L K G+ + D++ Sbjct: 4620 EVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLDVKLPQEYK 4679 Query: 4560 --------NKILEEDGTYTLL---------ILEAYPQDSGKYECVAINSAGEARCDAECV 4602 +K LE+D T++ I +D Y+ VA N++G CD E + Sbjct: 4680 AEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVL 4739 Query: 4603 V----SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 V +P + + ++ + PE +E K V E + G +++W+K Sbjct: 4740 VEERIKVPQIAN-IRGGSRLSQVAPEFMEQCKSTTVQENGTAIMEVRATGSQPLSIRWFK 4798 Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV------ 4712 + IK +MS + TL+IS +DEG Y CV N AG A L V Sbjct: 4799 NQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSD 4858 Query: 4713 ---------------TQPDQADNL-PAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755 T+P ++ P++ TPL ++ V+ G + + I+W Sbjct: 4859 GEDGATHGSPPKTRGTKPKKSSGAKPSIVTPLANMEVFSGDDVMLEVISGPEQVKKIEWF 4918 Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 ++ LI + P F + E L I +D G F C G SA+++V+ Sbjct: 4919 KDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVE 4974 Score = 159 bits (385), Expect = 7e-38 Identities = 105/402 (26%), Positives = 189/402 (47%), Gaps = 24/402 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-LI 4469 P FT +M V E + + G P P +KW R+ P+ + + + + LI Sbjct: 1963 PSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRVQGVTLI 2022 Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529 IR V D V+ +N+ G+ + ++V ++ + P F +NV G+ Sbjct: 2023 IRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS-------IRPIFGQKMKNVEGRIGE 2075 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKYECVA 4588 VR + +V GT V + + +++ R I+EE+ G + L I P+D+G+Y+C+A Sbjct: 2076 DVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIA 2135 Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648 +N AGE L ++ PQ P ++E + +G + S ++ G Sbjct: 2136 VNGAGEVTSKGY----LHVEEELTIPQF--IGDVPGVVE------LVQGDNYDLSLEVRG 2183 Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708 P P ++WY ++LI + Q+S + + T+ + +D G Y+C A N+AG + Sbjct: 2184 TPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQF 2243 Query: 4709 KLKVTQPDQADNLP--ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766 + V QP + + ++ L+ + V EG+ A+ + ++ PT++W R+G + E+ Sbjct: 2244 NINV-QPKRPEGTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRR 2302 Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 + E A L+I T+ ED GT+ C+ G+ TSA L Sbjct: 2303 VRSTLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHL 2344 Score = 157 bits (382), Expect = 2e-37 Identities = 140/543 (25%), Positives = 229/543 (42%), Gaps = 39/543 (7%) Query: 4289 VIKESRLRES-THQYAIPGDKVTSNTVAKSMAQR------YEDNLDQTEEVTEQRVQKKV 4341 VIK++RL ++ T++ D T++++A+ Q ED+L + +RV+ KV Sbjct: 357 VIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTKPEIEDSLRDVSALPGERVKFKV 416 Query: 4342 TQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEI-------EHKA 4394 + P P GK V ++ T E D+ + I E T+ ++A Sbjct: 417 RIGGK-PKPKVEWRKGKSVIEDGERFTIAEE-SDEVFSLIIQDLEETDAGRYKCVATNEA 474 Query: 4395 QTQERVVEGPVKPSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453 E + + V P F K + V E E G+P P I+W ++ ++ Sbjct: 475 GEAESMAQLTVNEELIGPRFEKMKESFTVVEGESVELVARVTGKPAPEIEWTKDGKTVRK 534 Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513 + + +++L I + +DS ++ A N+ GTA + L V+ K+ +G Sbjct: 535 TNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTA---- 590 Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 P + V T G L ++G + WLKNG +V+ R K DG L I Sbjct: 591 PEIVSELRPVEATEGDDAVLSCTISGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTI 650 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633 D G Y C+ N G A +K K K A A PE LK Sbjct: 651 KTTRADDQGDYTCIVRNELGSAE-----------SKTKLKV---IAFARPEFRTKLKPVK 696 Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE---YTLRISEAFPEDE 4690 EG+ ++ K+ G P P ++WY+G +I S F++ +E Y+L IS+ +D Sbjct: 697 AVEGEEVQLDVKVEGYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGLYSLVISKLQLDDT 756 Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750 G K VA N++G+ T A L+V + + A IVV EG + ++ + Sbjct: 757 GTIKVVATNASGKATSRADLEVKEREFAPEFEG-DEEGPIVVTEGNEVSIQLRVKANPNA 815 Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 + W ++G I E+ + G L I + EDTG + C A+ G+ S + V Sbjct: 816 DVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKV 875 Query: 4811 KSK 4813 + K Sbjct: 876 QVK 878 Score = 157 bits (380), Expect = 3e-37 Identities = 105/406 (25%), Positives = 175/406 (43%), Gaps = 21/406 (5%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 P K P E + V G+P P ++W++ + + S + K + Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMT 1627 Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529 + + ++DS ++ VA N+ G++ + NL V++K+ G P + V G Sbjct: 1628 VSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVIGNA----PDIITHLISKEVKEGG 1683 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589 V L+ V+G ++ W K+G + R + ++ +A D G+Y+CVA Sbjct: 1684 TVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVAT 1743 Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649 N G A+ A V++P+ KP+ K P E++E G +F +I Sbjct: 1744 NPLGSAQSSARLTVTVPS-----KPEFKQKLRPLEVVE---------GSEAKFDVRIKSY 1789 Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTA---DEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 P P V+WY+G I S Q++ D Y+L I ED YKCVA+N AG+ T Sbjct: 1790 PKPEVEWYRGTTKITDSLRHQITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTC 1849 Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766 A L V + Q + I+V EG I K P + W ++G L+ ++ Sbjct: 1850 RADLTVIEKQQPPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPEVSWYKDGRLVLDSIK 1909 Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812 + G+ + L++ N ED G++ C A G V + + V S Sbjct: 1910 QETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKVMS 1955 Score = 155 bits (376), Expect = 8e-37 Identities = 198/785 (25%), Positives = 308/785 (39%), Gaps = 98/785 (12%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827 +P F++ +QDL E+ EG A ++ V +P ++WYKD R I R+ F G Sbjct: 3734 KPSFLQRMQDL-EIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEEDGL 3790 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR---STVT-ADLGIPEQRRYIEK 883 L I D G Y N G+A +A + + S V+ ADL ++ E Sbjct: 3791 CMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARES 3850 Query: 884 TXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRV 943 T E PEF ++++ +KEGG F +R+ I + ++V Sbjct: 3851 TIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNR-EVKEGGVTKFASRV--ISKAPIKV 3907 Query: 944 EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003 EW KD R + + TF HD Y N + T V Sbjct: 3908 EWYKDDRLISSDWPRHTF--------------EHDEDLYAMNISNV--KVADGGPYTFVV 3951 Query: 1004 KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF 1063 S G +E YL E PRF LK +++EG +A Sbjct: 3952 -------SNKYGTVESKAYLNVLPEMEPEFEGI-----SPRFSVKLKN-QEVIEGSTARL 3998 Query: 1064 EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNA 1123 E R+ V WY + + + + + Q D + AL + V ED G Y VARN Sbjct: 3999 ECRIVGSP--VPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNI 4056 Query: 1124 AGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPL 1183 AG +A ++V+ + + S I R + ESK +P +I KP V L Sbjct: 4057 AGRDVCTADISVKHPDTDEESDIDA---VDARPL-ESKPSKPKTEI-----PKPEIVLGL 4107 Query: 1184 SNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHAT 1243 + V EG ++ CR P V WF +G+ + R++ G +L I Sbjct: 4108 RD-RFVVEGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCK 4164 Query: 1244 SADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVRE 1303 AD G Y N G A TSA + T E + ++ R ++++ Sbjct: 4165 LADAGIYKCEVSNVGGKAGTSAHL-----------TVEELPKSRPSVVASPPRFQEELKG 4213 Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363 ITV+ GT L + +G T +EW+ + + + G R R Sbjct: 4214 VITVV----------------GTTTKLSVPI--IGHPTPVIEWYKDDREVLEGGRIRFEQ 4255 Query: 1364 E----FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLE 1419 + F V+L + V D G Y C A N+ G +S ++V K+L E G Sbjct: 4256 DQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKV---KELDDEDSIQEGAM 4312 Query: 1420 KIQYLEDTSRYKKTDI-IDESVTIK----PRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474 + + DI + +S +K P F+ + + + + E + F C++ D Sbjct: 4313 SLPKSTSDEALRMEDIPVAQSTPLKRGEPPEFIRKLRD-QFIQEKETARFVCRVIGRPDP 4371 Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 EW + +P+T G R+ + D L+I D ED G+Y C + N GTD + RL Sbjct: 4372 T--YEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARL 4429 Query: 1535 TCRST 1539 T ++ Sbjct: 4430 TVEAS 4434 Score = 154 bits (373), Expect = 2e-36 Identities = 117/412 (28%), Positives = 182/412 (44%), Gaps = 27/412 (6%) Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465 K +P I + ++ V E E A G P P +WYR++ ++ S + + Sbjct: 5 KGDRPQIL-QPLEGVDVKEDENAILSCTISGTPTPNAEWYRDSIRVRESRRIKSEVVNGM 63 Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525 + L I+Q ED + V N GTA A L V V PSFT + V+ Sbjct: 64 ATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVP--------VKPSFTSKMKPVDA 115 Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKY 4584 GQ VR D V G+ DV W K + R +I+E + TL+I E +D+ Y Sbjct: 116 EEGQEVRFDVHVKGSPKPDVVWYKGSTMIGTHERFQIVEAAEDHVTLVISEVKLEDAETY 175 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFS 4643 + VA N G+ A+ V K PE I+ + I A G + + Sbjct: 176 KVVATNDVGKVTSRADLRV-------------KERQFAPEFIDEERGPIDATTGDEVTLT 222 Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 C + GKP P++ WYK KL+ S + + + + + A PED YKC A N G+ Sbjct: 223 CSVSGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGK 282 Query: 4704 VTVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 + A +KV P + P+ T L + EG+ ++ ++T K PTI+WL+ + Sbjct: 283 ASRAFDVKVKAP--KGDAPSFTIDLTHVRAIEGEESKLVCKVTGKPAPTIEWLKGELPVT 340 Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 + + E N A L+I +T D GT+ A +G + A+L V+ ++ Sbjct: 341 TSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERS 392 Score = 153 bits (372), Expect = 3e-36 Identities = 182/772 (23%), Positives = 306/772 (39%), Gaps = 71/772 (9%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGF 1234 +PVFVQ + EG ++ G P V+WF R + R + D G Sbjct: 4516 EPVFVQK-PETCRLKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGE 4572 Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTD-TQNEQAIEQIQLLE 1292 +L I+ D G Y A N GS A + V IE ++ + T+ E A + + Sbjct: 4573 CSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTEVEPAPAEPTPTK 4632 Query: 1293 DAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP 1352 +K + + P F+ L + + EG N+ L+ +L + V W+ + K Sbjct: 4633 IQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLDVKLPQ--EYKAEVAWYRDDKK 4690 Query: 1353 IKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412 ++ HR D L + V +D VY ATN G TSC V+ ++ + Sbjct: 4691 LEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASG--TTSCDCEVLVEERI---- 4744 Query: 1413 QHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVT 1472 + +I + SR + + P F+ + KS G + ++ Sbjct: 4745 ----KVPQIANIRGGSRLSQ---------VAPEFMEQCKSTTVQENGTAI---MEVRATG 4788 Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532 L + WFKN Q + G R + D + L I + +D G+Y C N GT + Sbjct: 4789 SQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEA 4848 Query: 1533 RLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEG 1592 LT + E G + R + + P T L N+E+ G Sbjct: 4849 LLTVEPMV-----SDGEDGATHGSPPKTRGTKPKKS-----SGAKPSIVTPLANMEVFSG 4898 Query: 1593 QRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTC 1652 E +I + K+EW+ +N+ ++ RFT T+ L I + +D G + C Sbjct: 4899 DDVMLE--VISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKC 4956 Query: 1653 RAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPV 1712 +N G A S +V + Y ES + A R ++ +R ++D + A Sbjct: 4957 VLLNDFGIASCSAEILVEEDEESYSESSADEATDR------NARIERRRSRDSIC--ALE 5008 Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL--TTMHDFGYVAL 1770 F +KD V + HF+ R+ G P+ +V W ++ + S R+ + + G +L Sbjct: 5009 FQQELKDREVLDGDTIHFDVRI--TGRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSL 5066 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830 +K +D G Y C A N G + L V+ + + ++ K Sbjct: 5067 LIKKATLDDEGDYRCVAANPAGTISCQAELLVE-----DVPEEEDTTDSKPAPATAPKPA 5121 Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQS 1889 +R+E +AP F L T + +G +A ++ R+ +P P+ V W K + + Sbjct: 5122 KRKE-------EAPVFTALLKDRT-IKDGDAARFDARVIGFPTPD--VTWLREDKQITPN 5171 Query: 1890 GHRYRTSNDFGFAALDILTVYG-EDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 H + + G ++T G +DSG Y C A N+ GQ + L V+ E Sbjct: 5172 SHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEGPE 5223 Score = 153 bits (371), Expect = 3e-36 Identities = 107/413 (25%), Positives = 180/413 (43%), Gaps = 26/413 (6%) Query: 4405 VKPSKP----PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 V+P +P P ++ V E EQA E G P P ++WYR+ +K S + Sbjct: 2247 VQPKRPEGTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRRVRST 2306 Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520 + + L+I + + ED + N G SA+L + R P F Sbjct: 2307 LENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNIIVATR--------PEFKEKL 2358 Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI--LEEDGTYTLLILEAYP 4578 V VT G + + +V G +V W ++ + R +I ++E G Y+L + E Sbjct: 2359 TKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQ 2418 Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638 +D+G Y+C+A+N AG++ C A+ V+ + P+ +T P +V EG Sbjct: 2419 EDAGMYKCIAVNKAGKSTCRADLEVN--ERQFAPEFETGEERGPI---------VVPEGG 2467 Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698 + P P V WYK K + + + + L+I+ A ED G YKC A Sbjct: 2468 ETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEAR 2527 Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757 N G + ++V P P L L+ + EG+ + + +++ K +PTI WL++ Sbjct: 2528 NKLGFADKSFTIRVEVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKD 2587 Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 G + + +G+ L I + D G + C A ++G +SA+L V Sbjct: 2588 GLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTV 2640 Score = 153 bits (370), Expect = 4e-36 Identities = 112/403 (27%), Positives = 178/403 (44%), Gaps = 24/403 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--L 4468 P F +K+ V E ++A+FEV G P P ++WY + I + F+I + L Sbjct: 2352 PEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSL 2411 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN--VNVT 4526 + +V ED+ ++ +A N+ G + C A+L V E++ P F + + V Sbjct: 2412 TVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQ-------FAPEFETGEERGPIVVP 2464 Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586 G L + V W K+GK +IR + T+ L I A +DSG Y+C Sbjct: 2465 EGGETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKC 2524 Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646 A N G A D + + + PKP P I++ L+ EG+AI+ C++ Sbjct: 2525 EARNKLGFA--DKSFTIRV----EVPKP----TGEEPTILQRLQPVDTIEGEAIKMECRV 2574 Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 GKP PT+ W K + + D TL I + DEG Y+C A NS+G Sbjct: 2575 SGKPEPTITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHS 2634 Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766 +A+L V + + + L L+D+ G+ A FK +++ P +QW R I Sbjct: 2635 SAELTVLEREARPRI--LEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGH 2692 Query: 4767 FQMIHEGNNAV-LLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 + + EG L I ED G + +G+V ++A L Sbjct: 2693 YIVRDEGRGYFSLTIEYIDYEDEGAYKAVVINDSGEVSSTAVL 2735 Score = 152 bits (369), Expect = 6e-36 Identities = 132/459 (28%), Positives = 199/459 (43%), Gaps = 59/459 (12%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F ++ + V E+ A EV G I+W++ IK ++ + L I Sbjct: 4763 PEFMEQCKSTTVQENGTAIMEVRATGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKI 4822 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV------------------ 4512 V +D ++ V N+ GTA C A L VE G G Sbjct: 4823 SPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPPKTRGTKPKKSSGA 4882 Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKILEEDGTYTL 4571 PS N+ V SG V L+ ++G + + + W K+ + ++ R + ED +TL Sbjct: 4883 KPSIVTPLANMEVFSGDDVMLEV-ISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTL 4941 Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVV----------SLPATKDK----PKPQTK 4617 I A D G ++CV +N G A C AE +V S D+ + +++ Sbjct: 4942 TIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIERRRSR 5001 Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK--YFQMSRTA 4675 + E + LKD+ V +G I F +I G+P P V WYK DK + SK F Sbjct: 5002 DSICALEFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIFVSEPET 5061 Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADN-----LPALTP--- 4726 Y+L I +A +DEGDY+CVA N AG ++ A+L V P++ D PA P Sbjct: 5062 GLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEEDTTDSKPAPATAPKPA 5121 Query: 4727 ------------LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PET-PDFQMIHE 4772 L+D + +G A+F ++ P + WLRE I P + P + +HE Sbjct: 5122 KRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALHE 5181 Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 G LLI +D+G + C A +AGQ T L V+ Sbjct: 5182 GEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVE 5220 Score = 151 bits (366), Expect = 1e-35 Identities = 164/635 (25%), Positives = 240/635 (37%), Gaps = 74/635 (11%) Query: 382 RIEISEKALAPQFVKVCQDR--DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439 R+ + EK + P F + D +V EG + ++ G+P P V WF RQ + N K Sbjct: 3615 RLAVKEKMVTPSFAEGDADEPCEVWEGAPIKLIVQIKGKPAPTVEWFKEKRQAKRLKNVK 3674 Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV----------V 489 L E H L+I DSG C A N +G ++ V E++ V V Sbjct: 3675 -LFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVNEQKVVMRRQPIPPGAV 3733 Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH-TDGGASTL 548 P F++R L + EG L R G P P I W KD I + + G L Sbjct: 3734 KPSFLQRMQDLEIVEGSAARLCVRVQGVPEPEIDWYKDNRVIREGGRVEFEFEEDGLCML 3793 Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXX 608 I A SD Y+C N AG A L+ L + Sbjct: 3794 VIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDA-DLDFAARKEARESTI 3852 Query: 609 XXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTM 668 E+ P EE PP+F + L++ EGG F +R+ + + Sbjct: 3853 ELISDDTSDEEKTEG--APKEEGA---PPEFTLVLRNREVKEGGVTKFASRV--ISKAPI 3905 Query: 669 KIEWLKNGQSIEAS-SRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLH 727 K+EW K+ + I + R T ++++ ++ + D G YT + G E+KA L+ Sbjct: 3906 KVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESKAYLN 3965 Query: 728 VTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRN 787 V P E P K ++QE IE G Sbjct: 3966 VLPEMEPEFEGISPRF---------SVKLKNQEVIE---------------------GST 3995 Query: 788 AHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847 A E ++ V P V WY+D P+ S + + + +L + + ED G Y A Sbjct: 3996 ARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVA 4053 Query: 848 VNKLGEAISTASIRVAARST-VTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPEST 906 N G + TA I V T +D+ + R K +P Sbjct: 4054 RNIAGRDVCTADISVKHPDTDEESDIDAVDARPLESKP-----------SKPKTEIP--- 4099 Query: 907 QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966 KPE ++D+ + EG F R V W KDG+P+ + R G Sbjct: 4100 -KPEIVLGLRDRF-VVEGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGA 4155 Query: 967 VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 +LTIK + DAG Y C N G+A TSA+LT+ Sbjct: 4156 QSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTV 4190 Score = 151 bits (365), Expect = 2e-35 Identities = 179/786 (22%), Positives = 312/786 (39%), Gaps = 69/786 (8%) Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484 E SR +T + + +P FV +P++ + EG F K+ + V+WF Sbjct: 4498 ETASRADQTPDEPTAESGEPVFVQKPETCR-LKEGDTARFNVKVNGSPEPF--VDWFLGR 4554 Query: 1485 QPVTIGHRFRPIH-DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543 + + R R D G +L I+D+ ED+G+Y C A N G+ L D + Sbjct: 4555 RMIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDEL 4614 Query: 1544 RS--TQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601 + T+ E + + +++ + + P+ + L + ++KEG+ + +L Sbjct: 4615 DAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLDVKL 4674 Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 + +V WY ++K L+ R T L I +D Y A NA G Sbjct: 4675 --PQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTT 4732 Query: 1662 VTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIR 1721 +V + + + G RL+Q+ AP F K Sbjct: 4733 SCDCEVLVEERIKVPQIANIRGG-SRLSQV------------------APEFMEQCKSTT 4773 Query: 1722 VAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSG 1781 V EN A E R G L + W +N I+ R+ D + L + V +D G Sbjct: 4774 VQENGTAIMEVRA--TGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEG 4831 Query: 1782 TYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVN 1841 Y C N+ G A + L V+ S + + K + + + Sbjct: 4832 LYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPPKTRGTKPKK----------SSG 4881 Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 P +T L S G E + P+ ++EW+ + ++++ R+ +++ Sbjct: 4882 AKPSIVTPLANMEVFS-GDDVMLE--VISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTR 4938 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 L I T +D G + C +N+ G A S + V+ E +S + A ++ + Sbjct: 4939 HTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDR------N 4992 Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021 +R +R DS +F + +K+ EV +G +H + +T P +V WY + + + Sbjct: 4993 ARIERRRSRDSICA--LEFQQELKDREVLDGDTIHFDVRIT--GRPEPKVVWYKDDKELV 5048 Query: 2022 QGHR--FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDT 2079 + R F + + G +L I A +D G Y C A N G + ++ L ++ Sbjct: 5049 ESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAG--------TISCQAELLVED 5100 Query: 2080 LDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDP 2139 + E+ + PKP + ++ + PVF TAL +K+GD A F+ RV I P Sbjct: 5101 VPEEEDTTDSKPAPATAPKPAKRKE--EAPVF-TALLKDRTIKDGDAARFDARV--IGFP 5155 Query: 2140 HLTIDWFHNGQKIRA-GHRY-RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197 + W ++I H + + H+ +L I +DSG Y C A N G+ Sbjct: 5156 TPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVG 5215 Query: 2198 TLKVAG 2203 L V G Sbjct: 5216 HLFVEG 5221 Score = 150 bits (363), Expect = 3e-35 Identities = 106/343 (30%), Positives = 156/343 (45%), Gaps = 35/343 (10%) Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467 +KP I T + VF + EV E + I+W+++N I++ P F + + T+ Sbjct: 4882 AKPSIVTP-LANMEVFSGDDVMLEVISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHT 4940 Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE--------------------KRRQG 4507 L I +D +F V N G A CSA ++VEE +RR+ Sbjct: 4941 LTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIERRRS 5000 Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED- 4566 R I F ++ V G + D ++TG V W K+ K++ R + E Sbjct: 5001 RDSICALEFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIFVSEPE 5060 Query: 4567 -GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV-SLPATKD----KPKPQT---- 4616 G Y+LLI +A D G Y CVA N AG C AE +V +P +D KP P T Sbjct: 5061 TGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEEDTTDSKPAPATAPKP 5120 Query: 4617 -KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS--R 4673 K P LKD+ + +G A F +++G P P V W + DK I P+ + M Sbjct: 5121 AKRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALH 5180 Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716 + ++L I+E +D G YKC+A NSAG+ T L V P+ Sbjct: 5181 EGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEGPE 5223 Score = 149 bits (362), Expect = 4e-35 Identities = 113/414 (27%), Positives = 180/414 (43%), Gaps = 33/414 (7%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 P I T + V E E G+P P I+WY++ ++ + ++ T S+ Sbjct: 1668 PDIITHLISK-EVKEGGTVTLECTVSGKPAPNIEWYKDG--LRFTATRRVMTTFDGSVAS 1724 Query: 4470 IRQVFVE--DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 + + D + VA N G+A+ SA L V + P F + + V Sbjct: 1725 VTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSK--------PEFKQKLRPLEVVE 1776 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE---DGTYTLLILEAYPQDSGKY 4584 G + D ++ +V W + K+ +R++I E D TY+L+IL +D+ Y Sbjct: 1777 GSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQITEPYEGDDTYSLIILNTTMEDAAMY 1836 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644 +CVA N AG+ C A+ V +K +P T + + I IV EG + S Sbjct: 1837 KCVAFNEAGKTTCRADLTVI-----EKQQPPTFLGDDGTQTI------IVKEGDDLNISA 1885 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 I GKP P V WYK +L+ S + + DE L + A ED G YKC A N G V Sbjct: 1886 TIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTV 1945 Query: 4705 TVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763 T +KV P+ T + + V EG + I+ KPT++W R+G IP Sbjct: 1946 TKTYNVKVMSTAPEGQAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVKWTRDG--IPV 2003 Query: 4764 TPDFQMIHEGN---NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 D+++ + + L+I N D G + C G T+ +++V ++ Sbjct: 2004 FEDYRISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS 2057 Score = 149 bits (361), Expect = 5e-35 Identities = 208/883 (23%), Positives = 346/883 (39%), Gaps = 115/883 (13%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576 P E+WEG A + V G P+ EW+ + K + + L I Sbjct: 3635 PCEVWEG--APIKLIVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPE 3692 Query: 2577 DAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDT 2636 D+G Y C+A N AG ++++ ++ M + P + Sbjct: 3693 DSGNYRCQATNDAGTVTKTFKV-------VVNE------------QKVVMRRQP---IPP 3730 Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696 G + P F ++ + +VEG L +V+ +P +I+W+K+ + G R++ F+ Sbjct: 3731 GAVK-PSFLQRMQDLE-IVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFE 3786 Query: 2697 F-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE-----------DRHWLLGES 2744 GL L I D G Y C +N G+A +A + IE D + + Sbjct: 3787 EDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKE 3846 Query: 2745 LHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPT 2804 +++ I F L N KEG F V S+ P Sbjct: 3847 ARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVI-SKAP- 3904 Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864 +K+EW+ +++ + S D+ HT+E D +Y +N K G Sbjct: 3905 IKVEWYKDDRLISS--------DWP------RHTFEHDEDLYAMNISNVK---VADGGPY 3947 Query: 2865 CTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLV 2924 N Y + KA L + + E P+ E P + + + + +++ Sbjct: 3948 TFVVSNKYGTVE---SKAYLNVLPEME------------PEFEGISPRFSVKLKNQ-EVI 3991 Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984 EG LE ++ P+++ WY + + L + ++++ D L + DV E D G Y Sbjct: 3992 EGSTARLECRIVGSPVPEVR--WYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHY 4049 Query: 2985 TCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDT 3044 A N G CT+ ++ +HP T+ I ++ + +P + Sbjct: 4050 KAVARNIAGRDV------CTADISV----KHPD-TDEESDIDAVDARPLESKPSKPKTEI 4098 Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 +P E +D + EG + T + WF +G+ + + R G Sbjct: 4099 PKP-EIVLGLRDRF-VVEGMSVRFNCRT--TSQPKPYVTWFKDGQPLASYGRYEVTSVAG 4154 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL--ECVDKSK----GQKPRFTTHIQNI 3158 L I K D+G Y C +N G+A S L E + KS+ PRF + + Sbjct: 4155 AQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPSVVASPPRFQ---EEL 4211 Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD----FGFVVLDIAYT 3214 +G+ + +V + P IEWY + + + RI+ D F V L I Sbjct: 4212 KGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDV 4271 Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274 + D G Y C A NK G DF+ AT+ +S+Q +++ + + P Sbjct: 4272 RLTDEGRYKCVAKNKSGTDFSSATVKVKELDDE--DSIQEGAMSLPKSTSDEALRMEDIP 4329 Query: 3275 ---STP--SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329 STP EPP+FI +++D + E ++A F R++ DP EW K + G Sbjct: 4330 VAQSTPLKRGEPPEFIRKLRDQF-IQEKETARFVCRVIGRPDPTY--EWLRGDKPITDGG 4386 Query: 3330 RYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 RY D L+I C E+ G Y+CV+TN G D+T A L Sbjct: 4387 RYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARL 4429 Score = 145 bits (352), Expect = 7e-34 Identities = 224/952 (23%), Positives = 370/952 (38%), Gaps = 138/952 (14%) Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 TVEW+ +Q ++ + + L I EDSG Y A N AG + + V Sbjct: 3657 TVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVV 3716 Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195 E K V I KP F+Q + + V EG Sbjct: 3717 N----------------------EQKVVMRRQPIPP-GAVKPSFLQRMQDLEIV-EGSAA 3752 Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYTVRA 1254 L R++ G P ++W+ + R + G R + + + G L I AT +D G Y Sbjct: 3753 RLCVRVQ--GVPEPEIDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVV 3810 Query: 1255 VNHLGSAHTSAIVRV--------IERSDIVTDTQNEQAIEQIQLL-EDAARRTKQVREDI 1305 N G A SA + + + +D+ + E I+L+ +D + K Sbjct: 3811 SNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELISDDTSDEEKTEGAPK 3870 Query: 1306 TVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365 P+F+ L N E EG R+ + ++VEW+ + + I + P + F Sbjct: 3871 EEGAPPEFTLVLRNREVKEGGVTKFASRV--ISKAPIKVEWYKDDRLISSDW---PRHTF 3925 Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425 ++ D +Y +N + A V++ K +ES+ + L + +E Sbjct: 3926 EH-----------DEDLYAMNISN-VKVADGGPYTFVVSNKYGTVESK--AYLNVLPEME 3971 Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485 E I PRF + K+ E VIEG EC++ V +V W+++ + Sbjct: 3972 P-----------EFEGISPRFSVKLKNQE-VIEGSTARLECRI--VGSPVPEVRWYRDNE 4017 Query: 1486 PVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRS 1545 P+ +++ D + AL + D+ ED G Y A N+ G D + ++ + Sbjct: 4018 PLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHP-----D 4072 Query: 1546 TQNEAGLEQIQV--LEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIP 1603 T E+ ++ + LE + +T++ P L++ + EG F R Sbjct: 4073 TDEESDIDAVDARPLESKPSKPKTEI------PKPEIVLGLRDRFVVEGMSVRFNCRT-- 4124 Query: 1604 VSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT 1663 S V W+ + +PL S R+ T+ G +L I C D+G Y C N G+A T Sbjct: 4125 TSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGT 4184 Query: 1664 SGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVA 1723 S V LP+ ++ V+ P F +K + Sbjct: 4185 SAHLTVEE-------------LPK--------------SRPSVVASPPRFQEELKGVITV 4217 Query: 1724 ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD----FGYVALNMKYVNPED 1779 +I G P +EW ++ + R+ D F V+L ++ V D Sbjct: 4218 VGTTTKLSVPII--GHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTD 4275 Query: 1780 SGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVA 1839 G Y C A N+ G +S+T V+ K +S E A+ + D + R ED+ VA Sbjct: 4276 EGRYKCVAKNKSGTDFSSAT--VKVKELDDEDSIQEGAMSLPKSTSDEA--LRMEDIPVA 4331 Query: 1840 VN------QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893 + + P FI +L + E ++A + CR+ PDP EW K + G RY Sbjct: 4332 QSTPLKRGEPPEFIRKLRDQF-IQEKETARFVCRVIGRPDPT--YEWLRGDKPITDGGRY 4388 Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953 +D L+I ED G Y C + N+ G ++ RL V++ I E L Sbjct: 4389 TIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPI-SKNIEKLLI 4447 Query: 1954 KIQYLEDDSRYKRAVQDDSFVVEKPQ-FGKP---IKNAEVTEGHPVHLEATL 2001 K ++++S + + + E P+ G+P K A+ PV EA L Sbjct: 4448 KAASMDEESMSQALAK---AIAESPELLGEPEPESKPADEPAKEPVEEEALL 4496 Score = 142 bits (345), Expect = 5e-33 Identities = 129/532 (24%), Positives = 216/532 (40%), Gaps = 46/532 (8%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP F + ++ + A+F ++ G P P W R P+ + +Y++ +++ + Sbjct: 4341 PPEFIRKLRDQFIQEKETARFVCRVIGRPDPTYEWLRGDKPITDGGRYTIMSDDE--GQT 4398 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190 L I DEG Y C + N G + + E + S E + Sbjct: 4399 LEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPISKNIEKLLIKAASMDEESMS 4458 Query: 191 YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250 Q + + + + + K E LL E + R T Sbjct: 4459 ---QALAKAIAESPELLGEPEPESKPADEPAKEPVEEEALLPETASRADQTP-------- 4507 Query: 251 QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310 D P QKP +L+EG A+F V+++G+P P V WF G+R+I + Sbjct: 4508 ------DEPTAESGEPVFVQKPETCRLKEGDTARFNVKVNGSPEPFVDWFL-GRRMIEED 4560 Query: 311 KHEIITTHN--HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368 I + +L + + + D+G Y +AEN +G I L V+ + + Sbjct: 4561 DRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTE 4620 Query: 369 QYITDTQQRETEERIEIS-----EKALAPQ--FVKVCQDRDVTEGKMTRFDCRVTGRPYP 421 + T+ + E+S E A AP+ F D+ V EG+ D ++ Sbjct: 4621 VEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLDVKLPQEYKA 4680 Query: 422 EVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480 EV W+ +D+++ DD H+I + +G+ H L I V++ D V VA N SG T+ C + Sbjct: 4681 EVAWYRDDKKLEDD--HRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEV 4738 Query: 481 NVIEKEQV--------------VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526 V E+ +V VAP+F+E+ + V+E ++ RA G+ I W K Sbjct: 4739 LVEERIKVPQIANIRGGSRLSQVAPEFMEQCKSTTVQENGTAIMEVRATGSQPLSIRWFK 4798 Query: 527 DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + I +++ +DG TL I + D Y C N AG+ A L Sbjct: 4799 NQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALL 4850 Score = 142 bits (344), Expect = 6e-33 Identities = 126/489 (25%), Positives = 203/489 (41%), Gaps = 63/489 (12%) Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441 + S + +E KA P P F+ K++ V E AR E G P+P Sbjct: 3950 VVSNKYGTVESKAYLNVLPEMEPEFEGISPRFSVKLKNQEVIEGSTARLECRIVGSPVPE 4009 Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV- 4500 ++WYR+N P+ S +Q+ LI++ V ED + AVA N G C+A++ V Sbjct: 4010 VRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVK 4069 Query: 4501 ------------------EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP 4542 E K + + I P L ++ V G VR + + T Sbjct: 4070 HPDTDEESDIDAVDARPLESKPSKPKTEIPKPEIVLGLRDRFVVEGMSVRFNCRTTSQPK 4129 Query: 4543 IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602 V W K+G+ + R ++ G +L I + D+G Y+C N G+A A Sbjct: 4130 PYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLT 4189 Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662 V ++ PK + +PP E LK I G + S I+G P P ++WYK D+ Sbjct: 4190 V-----EELPKSRPSVVASPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDRE 4244 Query: 4663 IKPSKYFQMSRTAD-EYT---LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718 + + + + +T L I + DEG YKCVA N +G +A +KV + D Sbjct: 4245 VLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVKELDDE 4304 Query: 4719 D-------NLPALTP-----LRDIVVYE------GQPAQFKTQITSKI------------ 4748 D +LP T + DI V + G+P +F ++ + Sbjct: 4305 DSIQEGAMSLPKSTSDEALRMEDIPVAQSTPLKRGEPPEFIRKLRDQFIQEKETARFVCR 4364 Query: 4749 -----KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803 PT +WLR I + + ++ + L I + ED G + C +T ++G Sbjct: 4365 VIGRPDPTYEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDT 4424 Query: 4804 TSAKLVVKS 4812 T+A+L V++ Sbjct: 4425 TTARLTVEA 4433 Score = 142 bits (344), Expect = 6e-33 Identities = 124/492 (25%), Positives = 214/492 (43%), Gaps = 54/492 (10%) Query: 4373 VGDKEITRKITSTETTEIEHKAQTQERVVEGPVK----PSKPPIFTKKMQPCRVFEHEQA 4428 + + E+ + T E E + V P K P+ P+F ++ +V E E Sbjct: 4609 IEEDELDAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENL 4668 Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488 +V+ E + WYR++ +++ I L I V ++D AV+ VA N Sbjct: 4669 SLDVKLPQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNA 4728 Query: 4489 GGTAKCSANLVVEEKRRQG-----RGGI----VPPSFTLTAQNVNVTSGQLVRLDTKVTG 4539 GT C ++VEE+ + RGG V P F ++ V ++ + TG Sbjct: 4729 SGTTSCDCEVLVEERIKVPQIANIRGGSRLSQVAPEFMEQCKSTTVQENGTAIMEVRATG 4788 Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599 ++P+ + W KN + ++ R K+ + TL I +D G Y CV N AG A C+A Sbjct: 4789 SQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEA 4848 Query: 4600 ----ECVVSLP---ATKDKPKPQT------KAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646 E +VS AT P P+T K++ A P I+ PL + V G + Sbjct: 4849 LLTVEPMVSDGEDGATHGSP-PKTRGTKPKKSSGAKPSIVTPLANMEVFSGDDVMLEVIS 4907 Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 + + ++W+K ++LI+ F ++ +TL I+ A +DEG +KCV N G + Sbjct: 4908 GPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASC 4967 Query: 4707 AAKLKVTQPDQA----------------------DNLPAL---TPLRDIVVYEGQPAQFK 4741 +A++ V + +++ D++ AL L+D V +G F Sbjct: 4968 SAEILVEEDEESYSESSADEATDRNARIERRRSRDSICALEFQQELKDREVLDGDTIHFD 5027 Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAA 4799 +IT + +P + W ++ + E+ + E + LLI +D G + C A A Sbjct: 5028 VRITGRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPA 5087 Query: 4800 GQVETSAKLVVK 4811 G + A+L+V+ Sbjct: 5088 GTISCQAELLVE 5099 Score = 142 bits (343), Expect = 8e-33 Identities = 116/460 (25%), Positives = 198/460 (43%), Gaps = 32/460 (6%) Query: 4380 RKITSTETTEIEHKAQTQERVVEG-PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438 RK T E+ + E EG P + PP FT ++ V E +F + Sbjct: 3844 RKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVISKA 3903 Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILI---IRQVFVEDSAVFAAVAENRGGTAKCS 4495 ++WY+++ I S D+ HTF L I V V D + V N+ GT + Sbjct: 3904 PIKVEWYKDDRLI--SSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESK 3961 Query: 4496 ANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554 A L V+ E + G + P F++ +N V G RL+ ++ G+ +V W ++ + + Sbjct: 3962 AYLNVLPEMEPEFEG--ISPRFSVKLKNQEVIEGSTARLECRIVGSPVPEVRWYRDNEPL 4019 Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-- 4612 + ++ ++ + L++ + +D G Y+ VA N AG C A+ V P T ++ Sbjct: 4020 IESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHPDTDEESDI 4079 Query: 4613 ----------KPQTKAANAP-PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661 KP P PEI+ L+D+ V EG ++ F+C+ +P P V W+K + Sbjct: 4080 DAVDARPLESKPSKPKTEIPKPEIVLGLRDRFVVEGMSVRFNCRTTSQPKPYVTWFKDGQ 4139 Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADN 4720 + ++++ A +L I + D G YKC N G+ +A L V + P + Sbjct: 4140 PLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPS 4199 Query: 4721 LPALTP-----LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE--TPDFQMIHEG 4773 + A P L+ ++ G + I P I+W ++ + E F+ EG Sbjct: 4200 VVASPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEG 4259 Query: 4774 NNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 + L I + D G + C A +G +SA + VK Sbjct: 4260 RFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVK 4299 Score = 140 bits (340), Expect = 2e-32 Identities = 120/510 (23%), Positives = 208/510 (40%), Gaps = 28/510 (5%) Query: 4308 KVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQ 4367 K TS + + + ++ + V K+V K +P +++ +V Sbjct: 1269 KTTSRADLTVKEREFAPEFETRDDTIDSEVNKEVEIKVTTGEPIRDSIN-TDVRAIGDSH 1327 Query: 4368 TQKEVVGDKEITRKITSTETTEIEHKAQTQERVV---EGPVKPSKPPIFTKKMQPCRVFE 4424 T +V K + + T A V P + PI +K+Q + E Sbjct: 1328 TCF-IVRAKLSDAGVYKCQATNAAGSASRSWEVKVKQSAPKTTGEEPIIIRKLQAQEIDE 1386 Query: 4425 HEQARFEVEFDG-EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483 A + +P P IKW R+ I+ + ++ L IR ++D V+ Sbjct: 1387 GSTANLVCKVTAAKPEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKV 1446 Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543 N GTA + ++V E + P F + V+ G+ R + K++ Sbjct: 1447 TLTNEYGTASSTCRVLVNEVGSR-------PIFQQKLKAVSTIEGESTRFEVKLSAMPRP 1499 Query: 4544 DVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601 V W K+ ++ R I EE+ G Y L+I + +D+G Y+ VA N+ G+ A Sbjct: 1500 TVEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALL 1559 Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661 V+ T P+ KA P++ EG +E + ++ GKP P ++W+K D+ Sbjct: 1560 RVNEVLT--VPEFMDKAEG-------PIEK---TEGDDLELTVRVRGKPQPELEWFKYDR 1607 Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721 + S +++T+ +S+ +D G Y+CVA N AG + L V + N Sbjct: 1608 TLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVIGNA 1667 Query: 4722 P-ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780 P +T L V EG + ++ K P I+W ++G T +G+ A + Sbjct: 1668 PDIITHLISKEVKEGGTVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTF 1727 Query: 4781 GNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 + D G + C AT G ++SA+L V Sbjct: 1728 TDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757 Score = 140 bits (340), Expect = 2e-32 Identities = 172/725 (23%), Positives = 284/725 (39%), Gaps = 63/725 (8%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT--YDG--MYH 4166 P F + V EG A+F R+ +PKP V W I + R+++T Y+G Y Sbjct: 1763 PEFKQKLRPLEVVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQITEPYEGDDTYS 1822 Query: 4167 FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQR 4226 I T D + + L VI + + P D+ TQ Sbjct: 1823 LIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK--------QQPPTFLGDDGTQ--- 1871 Query: 4227 TETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPE---TEWQQSVKRKKNEEY---YN- 4279 T + K E L I +P + K+ +Q +++ +E + +N Sbjct: 1872 --TIIVK---EGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNA 1926 Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339 K+++ + + ++L T Y + KV S T + A + + Q EV E K Sbjct: 1927 KMEDAGSYKCEANNKLGTVTKTYNV---KVMS-TAPEGQAPSFTSEMSQV-EVDEGGEVK 1981 Query: 4340 KVTQKPRIPDPS-ESTVHGKEV-HVAKQKQTQKEVVGDKEITRKITSTE------TTEIE 4391 P P+ + T G V + V G I R +T + T + + Sbjct: 1982 LYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQ 2041 Query: 4392 HKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI 4451 H + T V + +P IF +KM+ E RFE++ +G P+P + ++RE+ I Sbjct: 2042 HGSTTTTVQVIVTQRSIRP-IFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQI 2100 Query: 4452 KNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG 4510 + + I + +L IR ED+ + +A N G L VEE+ Sbjct: 2101 YDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEEL------ 2154 Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570 +P V + G L +V GT ++ W N + + R ++ T Sbjct: 2155 TIPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 + + DSG Y C A+N+AG V +PK + P I+ LK Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV-------QPK---RPEGTEPNIVSGLK 2264 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 V EG+ E + G P PT++WY+ +K S+ + + L I+E + ED Sbjct: 2265 SVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRRVRSTLENGIARLVITETWAEDM 2324 Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750 G YKC N GR + +A L + + + LT + V EG A+F+ ++ P Sbjct: 2325 GTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLT---KVEVTEGDRAKFEVRVKGYPYP 2381 Query: 4751 TIQWLREGALIPETPDFQM--IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 ++W I + F++ + E L +G +ED G + C A AG+ A L Sbjct: 2382 EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441 Query: 4809 VVKSK 4813 V + Sbjct: 2442 EVNER 2446 Score = 139 bits (336), Expect = 6e-32 Identities = 188/799 (23%), Positives = 316/799 (39%), Gaps = 75/799 (9%) Query: 921 IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF-NFGYVALTIKSVTVHDA 979 +KEG A F ++ G V+W R +E RI + G +L I + DA Sbjct: 4528 LKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDA 4585 Query: 980 GHYTCRAYNAIGQATTSANLTIVTKKDII-AESQH--PGGLEKIQYLEDASRYSKRTEEE 1036 G Y C A N G + A L + ++D + AE P E + + SK ++ E Sbjct: 4586 GVYKCVAENDDGSISCEAELIVDIEEDELDAEPTEVEPAPAEPTP-TKIQTEVSKPSKRE 4644 Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096 KP F L ++ EG++ + ++ PQ + V WY + K++ +RI Sbjct: 4645 PAPAPKPVFASELID-KQVKEGENLSLDVKL-PQ-EYKAEVAWYRDDKKLEDDHRITIIA 4701 Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRH 1156 L I V +D VY VVA NA+G + VE R + + RG Sbjct: 4702 AGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVLVEERIKVPQIANIRGG------ 4755 Query: 1157 IEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHN 1216 +S+ P F++ + G I +E R G + + WF N Sbjct: 4756 -------------SRLSQVAPEFMEQCKSTTVQENGTAI-MEVRAT--GSQPLSIRWFKN 4799 Query: 1217 GRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276 +++ G R K D L I D G Y N G+A A++ V +V Sbjct: 4800 QQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTV---EPMV 4856 Query: 1277 TDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQP 1336 +D ++ + +T+ + + P L N+E G +V LE P Sbjct: 4857 SDGEDGAT-------HGSPPKTRGTKPKKSSGAKPSIVTPLANMEVFSGDDVMLEVISGP 4909 Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396 +Q ++EWF + + I+ RF E L + + +D G++ C N G + Sbjct: 4910 --EQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFG--IA 4965 Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENV 1456 SC+ ++ ++D ES S + + + +R ++ D ++ F K E V Sbjct: 4966 SCSAEILVEED--EESYSESSAD--EATDRNARIERRRSRDSICALE--FQQELKDRE-V 5018 Query: 1457 IEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR--FRPIHDFGYVALDIIDLIAEDS 1514 ++G +HF+ ++ + KV W+K+ + + R F + G +L I +D Sbjct: 5019 LDGDTIHFDVRITGRPEP--KVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDE 5076 Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVT 1574 G Y C A N GT L + +T ++ R + Sbjct: 5077 GDYRCVAANPAGTISCQAELLVEDVPEEEDTTDSKPAPATAPKPAKRKE----------- 5125 Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFG 1633 +AP+ T LK+ IK+G A F+ R+I T V W +K + S + + G Sbjct: 5126 -EAPVFTALLKDRTIKDGDAARFDARVI--GFPTPDVTWLREDKQITPNSHPHMKALHEG 5182 Query: 1634 FV-ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK--KSIYLESQHEGALPRLNQ 1690 V +L I +DSG Y C A N+ G+ T G V K I + E L + Sbjct: 5183 EVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEGPEFKPIKGVQKPERKSSGLAR 5242 Query: 1691 LEDTSKYQRHSAQDEVITQ 1709 +E+ + ++A + +++ Sbjct: 5243 IEEVLTLKLYTATSDFLSE 5261 Score = 137 bits (331), Expect = 2e-31 Identities = 144/517 (27%), Positives = 209/517 (40%), Gaps = 69/517 (13%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 E +G +P F+V L N E + EG A E R+ + P +V WY + + L +++ Sbjct: 3973 EFEGISPRFSVKLKNQEVI-EGSTARLECRIVGSPVP--EVRWYRDNEPLIESEKYQMEQ 4029 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTID 3533 D L + ED G Y A N G V TA + V+ E ID Sbjct: 4030 DGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHPDT---------DEESDID 4080 Query: 3534 KIAA--LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV 3591 + A LE T P+ PE D + E S F CR + V Sbjct: 4081 AVDARPLESKPSKPKTEIPK------PEIVLGLRDRFVVEGMSVRFNCRT--TSQPKPYV 4132 Query: 3592 EWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651 WF +G+PL + R + + G L I DAG+Y C+ +N G Sbjct: 4133 TWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGG------------ 4180 Query: 3652 RQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGG 3711 K+GT + +EE R + +PPRF E+K I V G Sbjct: 4181 --------------KAGTSAHLTVEELPKSRPSVVA-----SPPRFQEELKGVITVV-GT 4220 Query: 3712 PVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND----FGFIALDIDYIYARDAGE 3767 + +G PT I+W+ + R G R+ D F ++L I + D G Sbjct: 4221 TTKLSVPI--IGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGR 4278 Query: 3768 YTCRATNKWGSATTTAKITCSAKRDIVLESQLPQG-MSGEKIKELERGRISDAP--KEEP 3824 Y C A NK G+ ++A + D E + +G MS K E R+ D P + P Sbjct: 4279 YKCVAKNKSGTDFSSATVKVKELDD---EDSIQEGAMSLPKSTSDEALRMEDIPVAQSTP 4335 Query: 3825 IV-STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883 + PP+FI +++ ++E E RF CRV + DP EW R K + G RY + D Sbjct: 4336 LKRGEPPEFIRKLRDQFIQEKETARFVCRVIGRPDPTY--EWLRGDKPITDGGRYTIMSD 4393 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920 +L+I ED G Y C + N G D T A ++ Sbjct: 4394 DEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLT 4430 Score = 137 bits (331), Expect = 2e-31 Identities = 182/760 (23%), Positives = 304/760 (40%), Gaps = 77/760 (10%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH-DFGYVA 1769 PVF + R+ E A F ++ G P+ V+W IE +R+ D G + Sbjct: 4517 PVFVQKPETCRLKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECS 4574 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ-SKASLQLE-SQHESALQKIQQLEDS 1827 L + ++ ED+G Y C A N+ G + L V + L E ++ E A + + Sbjct: 4575 LVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTEVEPAPAEPTPTKIQ 4634 Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887 + + E A P F ++L ++ EG++ + ++ + V WY + K L Sbjct: 4635 TEVSKPSKREPAPAPKPVFASELIDK-QVKEGENLSLDVKLPQ--EYKAEVAWYRDDKKL 4691 Query: 1888 QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947 + HR L I V +D Y A N G + V+ + + Sbjct: 4692 EDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVLVEERIKV----- 4746 Query: 1948 HESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDP 2007 +I + SR + P+F + K+ V E +E T Sbjct: 4747 -----PQIANIRGGSRLSQVA---------PEFMEQCKSTTVQENGTAIMEVRAT--GSQ 4790 Query: 2008 TMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067 + + W+ N + ++ G R K + D + L I +D G YMC +N G A + + Sbjct: 4791 PLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALL 4850 Query: 2068 KVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRA 2127 V+ D + K KP ++ G +P +T L ++E + GD Sbjct: 4851 TVEPM------VSDGEDGATHGSPPKTRGTKP--KKSSGAKPSIVTPLANME-VFSGD-- 4899 Query: 2128 HFECRVEPINDPHLT--IDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCK 2185 + +E I+ P I+WF + + IR R+ T + L I +D G + C Sbjct: 4900 --DVMLEVISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCV 4957 Query: 2186 ATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPK--ISPPR 2243 N G + +C+ + IL + + EA + RIE + I Sbjct: 4958 LLNDFG--IASCSAE-------ILVEEDEESYSESSADEATDRNARIERRRSRDSICALE 5008 Query: 2244 FVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGYVS 2301 F EL+ V +G T HF+ ++ +P ++ +Y + K L + R F + G S Sbjct: 5009 FQQELK-DREVLDGDTIHFDVRITGRPEP--KVVWYKDDKELVESKRIIFVSEPETGLYS 5065 Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361 L I+ +D G+Y A N G T++ + ++ E E E + + A P Sbjct: 5066 LLIKKATLDDEGDYRCVAANPAG--------TISCQAELLVEDVPEE--EDTTDSKPA-P 5114 Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421 P+ P + PVFT L++ I++G A FD R+I G PT V W R +K I Sbjct: 5115 ATAPK-PAKRKEEAPVFTALLKD-RTIKDGDAARFDARVI--GFPTPDVTWLREDKQITP 5170 Query: 2422 SS--RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 +S + H+ S+ I+ +D GVY C A N G+ Sbjct: 5171 NSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQ 5210 Score = 136 bits (330), Expect = 3e-31 Identities = 126/505 (24%), Positives = 206/505 (40%), Gaps = 48/505 (9%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS-LLIKQIGPGDEGE 143 +G + + G P+P VSW + +++ K R + GD S L++ D G Sbjct: 1877 EGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQETR---KRGDESHLVVFNAKMEDAGS 1933 Query: 144 YTCTARNQYGEAICSVYIQ-----PEGXXXXXXXXXXXXXYRHVSETVEHKAYGT-QGYT 197 Y C A N+ G + ++ PEG V E E K Y GY Sbjct: 1934 YKCEANNKLGTVTKTYNVKVMSTAPEGQAPSFTSEMSQV---EVDEGGEVKLYFLISGYP 1990 Query: 198 TEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEID 257 + T+ S D +V + + E + K + +T + Sbjct: 1991 KPTVKWTRDGIPVFEDYRISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQ 2050 Query: 258 RSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316 + S P QK +N + + G D +F++Q+ G P P VT+ + +++ + ++ I+ Sbjct: 2051 VIVTQRSIRPIFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVE 2110 Query: 317 THNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQ 375 N L +RNT+ D+G Y CI +G A E ++ Y Sbjct: 2111 EENGLFVLTIRNTRPEDAGEYQ--------CIAVNG--AGEVTSKGY------------- 2147 Query: 376 QRETEERIEISEKALAPQFV-KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434 + + E+ PQF+ V ++ +G V G P PE+ W+ N+R I Sbjct: 2148 -------LHVEEELTIPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYA 2200 Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE-QVVAPKF 493 ++ S + + NVTL DSG+ C A N +G + Q +NV K + P Sbjct: 2201 TSRVQLSFISS-KATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNI 2259 Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553 V ++ V+EGE L GTPTP + W +DG+ + + +R + G + L I Sbjct: 2260 VSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRRVRSTLENGIARLVITET 2319 Query: 554 KASDAAWYQCTAQNVAGSTATRARL 578 A D Y+C +N G T+T A L Sbjct: 2320 WAEDMGTYKCQVRNDLGRTSTSAHL 2344 Score = 133 bits (321), Expect = 4e-30 Identities = 172/728 (23%), Positives = 282/728 (38%), Gaps = 78/728 (10%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY----DGMYH 4166 P F + V EGE + +V G+PKP + W IV R+K+ DG+Y Sbjct: 686 PEFRTKLKPVKAVEGEEVQLDVKVEGYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGLYS 745 Query: 4167 FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQR 4226 I K + DTG I+V+ L+V R + AP DE Sbjct: 746 LVISKLQLDDTGTIKVVATNASGKATSRADLEVKER--------EFAPEFEGDEEGPIVV 797 Query: 4227 TETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN-KLQELE 4285 TE E + + R +D + +P I E ++ +KR+ E + LE Sbjct: 798 TEGN-EVSIQLRVKANPNADVDWFKDGRP--IYEST---KRDIKRRGEEHTLAIHVSSLE 851 Query: 4286 NEQVIK---ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVT 4342 + V K +RL +++ + + A + + +TEE E +++ T Sbjct: 852 DTGVYKCEASNRLGKASRSFDVKVQVKGPKGEAPIILSKLRPV--ETEEGEETKLKCTFT 909 Query: 4343 QKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGD------KEITRKITSTETTEIEHK--- 4393 KP E T G + + + Q + D KE T I++ Sbjct: 910 GKPA--PTCEWTRDG--IRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGT 965 Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453 T V+ V+ P+ +K++ V E+A F + G + W+++ + + Sbjct: 966 VSTSAEVLVNEVEKGVGPVIEEKLKDVTVMPGEEAEFSIRVSGRAE--VDWFKDEVMLND 1023 Query: 4454 SPDFQIHTFST-KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK----RRQGR 4508 F + + L I V ED + + N G A L ++E Sbjct: 1024 EGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIKEAIVAPEEVDA 1083 Query: 4509 GGIVP-----PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563 VP P T ++V V G+ L+ V+G+ V W K+ K++ R K Sbjct: 1084 AETVPIEGSAPKITKPLESVEVNEGEDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEK 1143 Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623 + L+ +A P+D G+Y+C IN G+A E V++ + +P+ K +P Sbjct: 1144 LDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLS-----RPEFKIKMSPV 1198 Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683 E V EG F ++ G P V+W+KG I+ S + + + YT+ I+ Sbjct: 1199 E---------VTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIA 1249 Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743 ED G Y+CVA N+AG+ T A L V + + A D V + + K Sbjct: 1250 NVTLEDAGGYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTIDSEV--NKEVEIKVT 1307 Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803 I+ +I D + I G++ I D G + C+AT AAG Sbjct: 1308 TGEPIRDSI-----------NTDVRAI--GDSHTCFIVRAKLSDAGVYKCQATNAAGSAS 1354 Query: 4804 TSAKLVVK 4811 S ++ VK Sbjct: 1355 RSWEVKVK 1362 Score = 132 bits (318), Expect = 9e-30 Identities = 97/358 (27%), Positives = 153/358 (42%), Gaps = 34/358 (9%) Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQG--RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538 FAA E R T + ++ +E++ +G + PP FTL +N V G + + ++V Sbjct: 3841 FAARKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVI 3900 Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 PI V W K+ + + D E D Y + I D G Y V N G Sbjct: 3901 SKAPIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVES 3960 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 A V P+ + + P LK++ V EG C+IVG P+P V+WY Sbjct: 3961 KAYLNVL-------PEMEPEFEGISPRFSVKLKNQEVIEGSTARLECRIVGSPVPEVRWY 4013 Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD- 4716 + ++ + S+ +QM + D + L + + ED+G YK VA N AGR A + V PD Sbjct: 4014 RDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHPDT 4073 Query: 4717 --QAD------------------NLP---ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753 ++D +P + LRD V EG +F + TS+ KP + Sbjct: 4074 DEESDIDAVDARPLESKPSKPKTEIPKPEIVLGLRDRFVVEGMSVRFNCRTTSQPKPYVT 4133 Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 W ++G + +++ L I + D G + C + G+ TSA L V+ Sbjct: 4134 WFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVE 4191 Score = 131 bits (317), Expect = 1e-29 Identities = 122/518 (23%), Positives = 202/518 (38%), Gaps = 42/518 (8%) Query: 68 EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127 E P F +GG K + G P P V WTR P+ E + SM + G Sbjct: 1959 EGQAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRVQG 2018 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVY-IQPEGXXXXXXXXXXXXXYRHVSETV 186 V+L+I+ + DEG Y CT +NQ+G +V I + + E V Sbjct: 2019 -VTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRSIRPIFGQKMKNVEGRIGEDV 2077 Query: 187 --EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLR--EVSFRESITK 242 E + GT R+++++ Y G ++ + R R + + I Sbjct: 2078 RFEIQVEGTPVPAVTFHRESEQI-YDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAV 2136 Query: 243 RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302 GE + ++ L P I P +L +G + +++ G PRP + W+ N Sbjct: 2137 NGAGEVTSKGYLHVEEEL--TIPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHN 2194 Query: 303 GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362 + + +++ ++ + T+ + N DSG Y A N G T S Sbjct: 2195 ERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG-------------TGS- 2240 Query: 363 VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422 Q+ + Q + E P V + +V EG+ + V+G P P Sbjct: 2241 -----KQFNINVQPKRPE--------GTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPT 2287 Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 + W+ + ++++ + + E+G L+IT D G C RN G T+ LN+ Sbjct: 2288 LEWYRDGLRVKESRRVRSTL-ENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346 Query: 483 IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT- 541 I P+F E+ + + V EG+ R G P P + W I+ I + Sbjct: 2347 I---VATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEIESV 2403 Query: 542 -DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + G +L + DA Y+C A N AG + RA L Sbjct: 2404 KETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441 Score = 130 bits (313), Expect = 4e-29 Identities = 103/417 (24%), Positives = 173/417 (41%), Gaps = 21/417 (5%) Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ 4458 R+ EG ++PS I + +P +E G PLP +++ ++ P+ S + Sbjct: 2736 RLAEGMIEPSFIGI---EFEPITAYEGSDIDLTFYVKGRPLPTVEFLKDEVPVFKSDRTE 2792 Query: 4459 IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL 4518 + + + L + + V DSA + AVA+N+ G A+ S L+V+ KR + G P Sbjct: 2793 LTSNGNRHTLYLSDLAVRDSATYKAVAKNKAGVARRSVELLVKPKRGL-KPGEAAPEIVQ 2851 Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP 4578 + V G +L +VTGT + W K+ ++P+ R I Y L LE Sbjct: 2852 RLKACEVPEGSSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEA 2911 Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638 +D G+Y VA N G AE ++ P+ +PP L V EG Sbjct: 2912 RDEGRYMLVAKNHLGSVSTSAELIIE-PSV------------SPPSFRHRLTAVEVDEGD 2958 Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCV 4696 F ++ +P +V+WYK + I +F++ +E Y+L IS D G YKC Sbjct: 2959 ETRFDVRLKKEP-TSVEWYKEQQRIFTDGHFEVIEGEEECLYSLVISNTKVADAGGYKCT 3017 Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756 A N +G+ + A+L V + + EG + P I+W + Sbjct: 3018 ALNESGKSSTRAELLVNERLIPPGFEG-PDHGSYELQEGDTITLDAVVKGNPYPEIRWYK 3076 Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + L E+ + L + + +D+G + C G S + V++K Sbjct: 3077 DEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAK 3133 Score = 130 bits (313), Expect = 4e-29 Identities = 191/800 (23%), Positives = 307/800 (38%), Gaps = 83/800 (10%) Query: 734 IERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQ 793 +E + PET Q D ES E Q+P+ R L+EG A F + Sbjct: 4490 VEEEALLPETASRADQTPDEPT---AESGEPVFVQKPETCR-------LKEGDTARFNVK 4539 Query: 794 LTPVSDPTMRVEWYKDGRPITASSRIT-SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852 + +P V+W+ R I RI + G SL IM + EDAG Y A N G Sbjct: 4540 VNGSPEPF--VDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDG 4597 Query: 853 EAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFK 912 A + V + E T P KP F Sbjct: 4598 SISCEAELIVDIEEDELDAEPTEVEPAPAEPTPTKIQTEVSKPSKRE---PAPAPKPVFA 4654 Query: 913 TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIK 972 + + D+ +KEG + +L + V W +D + +E RIT LTI Sbjct: 4655 SELIDK-QVKEGENLSLDVKLPQ--EYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIF 4711 Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKR 1032 V++ D Y A NA G TTS + ++ ++ I + +I + SR S+ Sbjct: 4712 GVSIKDEAVYKVVATNASG--TTSCDCEVLVEERI--------KVPQIANIRGGSRLSQ- 4760 Query: 1033 TEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRI 1092 P F+ K T + E +A E R L ++ W+ N + I RI Sbjct: 4761 --------VAPEFMEQCKSTT-VQENGTAIMEVRATGSQPL--SIRWFKNQQTIKYGGRI 4809 Query: 1093 QTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYE 1152 + D + L I+ V +D G+Y V N AG A A +TVE S G Sbjct: 4810 KMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPP 4869 Query: 1153 KTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVE 1212 KTR + K S +KP V PL+N V G ++ LE P + ++E Sbjct: 4870 KTRGTKPKK----------SSGAKPSIVTPLAN-MEVFSGDDVMLEVISGP--EQVKKIE 4916 Query: 1213 WFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 WF + + RF + L I AT D G + +N G A SA + V E Sbjct: 4917 WFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEED 4976 Query: 1273 SDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLEC 1332 + +++ ++A ++ +E RR+ R+ I + +F + L + E ++G +H + Sbjct: 4977 EESYSESSADEATDRNARIE--RRRS---RDSICAL---EFQQELKDREVLDGDTIHFDV 5028 Query: 1333 RLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQ 1390 R+ G +V W+ + K + R F E +L + +D G Y C A N Sbjct: 5029 RI--TGRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANP 5086 Query: 1391 LGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRP 1450 G SC ++ + + E + + + +K + + +K R Sbjct: 5087 AG--TISCQAELLVED--VPEEEDTTDSKPAPATAPKPAKRKEEAPVFTALLKDR----- 5137 Query: 1451 KSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH--RFRPIHDFGYVALDIID 1508 + +G F+ ++ + V W + + +T + +H+ +L I + Sbjct: 5138 ----TIKDGDAARFDARV--IGFPTPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITE 5191 Query: 1509 LIAEDSGIYTCRAVNLVGTD 1528 +DSG+Y C A N G D Sbjct: 5192 GGYKDSGVYKCIAKNSAGQD 5211 Score = 129 bits (311), Expect = 6e-29 Identities = 196/821 (23%), Positives = 326/821 (39%), Gaps = 105/821 (12%) Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS-DFGFVVLDIAYTQNHDS 3219 LK+G +A F V P+ ++W+ + + RI+ D G L I D+ Sbjct: 4528 LKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDA 4585 Query: 3220 GEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP----- 3274 G Y C A N G +I+C + V +E + D A+ E+E T Sbjct: 4586 GVYKCVAENDDG------SISCEAELIVDIEEDELD--AEPTEVEPAPAEPTPTKIQTEV 4637 Query: 3275 STPSA-EP-----PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG 3328 S PS EP P F +++ D ++ EG++ + +L + +V W+ + KKL Sbjct: 4638 SKPSKREPAPAPKPVFASELID-KQVKEGENLSLDVKLP--QEYKAEVAWYRDDKKLEDD 4694 Query: 3329 HRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPR 3388 HR + L I ++ Y+ VATN G S + E I Q+ Sbjct: 4695 HRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVLV---EERIKVPQIAN 4751 Query: 3389 GMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTD 3448 + GG Q + M + K T+V+E A E R T + Sbjct: 4752 -IRGGSRLSQVAPEFMEQCKSTTVQENG--------------------TAIMEVRATGSQ 4790 Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508 L + W+ N +++K G R + D L+ISP +D G Y+C N G A A Sbjct: 4791 P--LSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEA 4848 Query: 3509 SMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI 3568 + V E + G +G A G P+ SG P T +++ Sbjct: 4849 LLTV--------EPMVSDGEDG------ATHGSPPKTRGTKPKKSSGAKPSIVTPLANME 4894 Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAG 3628 + E +I + ++EWF + + + R ++ L I D G Sbjct: 4895 VFSGDDVMLE--VISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEG 4952 Query: 3629 LYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE 3688 ++ C N G A+ S ++ V+ + E S T+ ++E + +E Sbjct: 4953 IFKCVLLNDFGIASCSAEILVEEDE----ESYSESSADEATDRNARIERRRSRDSICALE 5008 Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748 F E+KD +V +G +HFD R+ G P ++ W+ + + R+ ++ Sbjct: 5009 --------FQQELKDR-EVLDGDTIHFDVRI--TGRPEPKVVWYKDDKELVESKRIIFVS 5057 Query: 3749 --DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806 + G +L I D G+Y C A N G+ I+C A+ +L +P+ E Sbjct: 5058 EPETGLYSLLIKKATLDDEGDYRCVAANPAGT------ISCQAE---LLVEDVPE----E 5104 Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866 + + + APK P F +K T+++ + RF+ RV P + W Sbjct: 5105 EDTTDSKPAPATAPKPAKRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPD--VTWL 5162 Query: 3867 RNGK-LLPSGHRYRTVYDMGFV-SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924 R K + P+ H + G V SL I +DSG Y C A N G+D T + + Sbjct: 5163 REDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEG- 5221 Query: 3925 PDIILQNQVPRGMKRSEALTQME--ATIKKYT-SEVYLTED 3962 P+ V + ++S L ++E T+K YT + +L+E+ Sbjct: 5222 PEFKPIKGVQKPERKSSGLARIEEVLTLKLYTATSDFLSEE 5262 Score = 128 bits (310), Expect = 8e-29 Identities = 95/339 (28%), Positives = 154/339 (45%), Gaps = 29/339 (8%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P I N ++ G D +V ++ WFK+ + + + + + + TL + Sbjct: 4884 PSIVTPLANMEVFSGDDVMLEVISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTI 4943 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 D G + + N G S + VE ESY + + TD R R Sbjct: 4944 ATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADE-ATDRNARIERRRSRD 5002 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE- 444 S AL +F + +DR+V +G FD R+TGRP P+V W+ +D+++ + I V+E Sbjct: 5003 SICAL--EFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVES-KRIIFVSEP 5059 Query: 445 -SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL---NVIEKEQ--------VVAPK 492 +G ++L+I TL D G CVA N +G + Q L +V E+E APK Sbjct: 5060 ETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEEDTTDSKPAPATAPK 5119 Query: 493 FVER------FSTL----NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN--PELRIH 540 +R F+ L +++G+ +AR +G PTP +TW ++ I PN P ++ Sbjct: 5120 PAKRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKAL 5179 Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579 +G +L I D+ Y+C A+N AG T L+ Sbjct: 5180 HEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLF 5218 Score = 125 bits (302), Expect = 8e-28 Identities = 225/953 (23%), Positives = 367/953 (38%), Gaps = 151/953 (15%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 EG + L Q++ + P +EWFK +K + L I +DSG Y Sbjct: 3640 EGAPIKLIVQIKGKPAPT--VEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNY 3697 Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXV 2775 C+ATN G T + + ++ ++ P GA+ Sbjct: 3698 RCQATNDAGTVTKTFKVVVNEQKVVMRRQPIPP-----GAVKPS---------------- 3736 Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLD 2834 F+ + ++ EG V+ +P +I+W+ +N+ + G R + + L Sbjct: 3737 FLQRMQDLEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEEDGLCMLV 3794 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL--RCTG-DKNIY-FDTQHPQGKAGLEA-VEQ 2889 I + D G Y C +N+ G A S L G D + D K E+ +E Sbjct: 3795 IRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIEL 3854 Query: 2890 AEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949 + + + P E PE+ + + ++ EG V +V K +K+EWY Sbjct: 3855 ISDDTSDEEKTEGAPKEEGAPPEFTL-VLRNREVKEGGVTKFASRVISK--APIKVEWYK 3911 Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL 3009 + +++ +SD+ T +E D +Y N + T ++K Sbjct: 3912 DDRLI--------SSDWPRHT------FEHDEDLYAMNISNVKVADGGPYTFVVSNKYGT 3957 Query: 3010 IERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYE 3069 +E + L P +P+ + G P F+ K+ ++ EG A E Sbjct: 3958 VESKAY----------------LNVLPEMEPEFE-GISPRFSVKLKN-QEVIEGSTARLE 3999 Query: 3070 ASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKW 3129 ++ G + W+ + + + S + + L + D G Y A N Sbjct: 4000 CRIV--GSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIA 4057 Query: 3130 GQ----AEISVK---------LECVD----KSKGQKPRFTTHIQNIE---GLKD-----G 3164 G+ A+ISVK ++ VD +SK KP+ T I E GL+D G Sbjct: 4058 GRDVCTADISVKHPDTDEESDIDAVDARPLESKPSKPK--TEIPKPEIVLGLRDRFVVEG 4115 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 S F C P + W+ +GQP+ R + S G L I + D+G Y C Sbjct: 4116 MSVRFNCRTT--SQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKC 4173 Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284 N G+ T A L + L K R PS A PP+F Sbjct: 4174 EVSNVGGKAGTSA-------------HLTVEELPKSR------------PSVV-ASPPRF 4207 Query: 3285 ITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD----FGIV 3340 +++ V +V G + ++ P +EW+ + +++ G R R D F IV Sbjct: 4208 QEELKGVITVV-GTTTKLSVPII--GHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIV 4264 Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400 L I + G Y+CVA NK G D + A +K KE LD + EG + ++ Sbjct: 4265 SLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKV--KE---LDDE-DSIQEGAMSLPKST 4318 Query: 3401 EDSMVRRKDTSVEE----EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456 D +R +D V + ++G+ P F L + + ++E E A F R+ DP EW Sbjct: 4319 SDEALRMEDIPVAQSTPLKRGEPPEFIRKLRD-QFIQEKETARFVCRVIGRPDPTY--EW 4375 Query: 3457 YWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516 K + G R+ D LEI+ ED G Y C + N+ G TTA + V+ R Sbjct: 4376 LRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASR 4435 Query: 3517 NIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESG---NPPEFTTTPSD 3566 + K +E + K A+++ S + AES PE + P+D Sbjct: 4436 R-----PISKNIEKLLIKAASMDEESMSQALAKAIAESPELLGEPEPESKPAD 4483 Score = 123 bits (297), Expect = 3e-27 Identities = 121/510 (23%), Positives = 214/510 (41%), Gaps = 48/510 (9%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G + +++ NP V W + P+ E K ++ + +++ + + D G Y Sbjct: 799 EGNEVSIQLRVKANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLE--DTGVY 856 Query: 145 TCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY----GTQGYTT 198 C A N+ G+A S V +Q +G E E K G T Sbjct: 857 KCEASNRLGKASRSFDVKVQVKGPKGEAPIILSKLRPVETEEGEETKLKCTFTGKPAPTC 916 Query: 199 EQSR-----QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIS 253 E +R ++ ++ + T+ SST K T + L + + + + V S + Sbjct: 917 EWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGT--VSTSAEVLV 974 Query: 254 TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE 313 E+++ +GPV I +K ++ + G +A+F +++SG R V WFK+ + ++N Sbjct: 975 NEVEKGVGPV----IEEKLKDVTVMPGEEAEFSIRVSG--RAEVDWFKD-EVMLNDEGRF 1027 Query: 314 IIT--THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYI 371 I+ + +L + + + D G Y L N +G + T L ++ + I Sbjct: 1028 IMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIK------------EAI 1075 Query: 372 TDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ 431 ++ + E + I + AP+ K + +V EG+ +C V+G P P V W + + Sbjct: 1076 VAPEEVDAAETVPI--EGSAPKITKPLESVEVNEGEDFDLECVVSGSPSPTVEWTKDLVK 1133 Query: 432 IRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGE--TAFQCRLNVIEKEQV 488 +R Y K ++ GN A L+ D G C N+ G+ T + ++NV+ + Sbjct: 1134 LRTSYRLKEKLD--GNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSR--- 1188 Query: 489 VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548 P+F + S + V EG R G P ++ W K I + D T+ Sbjct: 1189 --PEFKIKMSPVEVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYTFTADKNRYTM 1246 Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARL 578 I DA Y+C A N AG T +RA L Sbjct: 1247 VIANVTLEDAGGYRCVATNTAGKTTSRADL 1276 Score = 123 bits (296), Expect = 4e-27 Identities = 134/511 (26%), Positives = 210/511 (41%), Gaps = 58/511 (11%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT-T 960 +P KP F ++D + I EG A R++ + + ++W KD R + R+ Sbjct: 3728 IPPGAVKPSFLQRMQD-LEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFE 3784 Query: 961 FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI--------VTKKDIIAESQ 1012 F G L I+ T D G Y C NA G+A SA L I V+ D+ ++ Sbjct: 3785 FEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAAR 3844 Query: 1013 HPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSD 1072 I+ + D + ++TE K P + ++ EG F +RV S Sbjct: 3845 KEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRV--ISK 3902 Query: 1073 LTMTVEWYFNGKQITSANRIQTY-HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSA 1131 + VEWY + + I+S T+ HD A++I++V+ D G YT V N G Sbjct: 3903 APIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYG------ 3956 Query: 1132 SMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSE 1191 TVE+++ ++ L E +EP + E IS P F L N V E Sbjct: 3957 --TVESKAYLNV------LPE----------MEP--EFEGIS---PRFSVKLKN-QEVIE 3992 Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251 G LECR+ +G P V W+ + + +++ D AL + + D G Y Sbjct: 3993 GSTARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYK 4050 Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP 1311 A N G +A + V DT E I+ + DA + + T + P Sbjct: 4051 AVARNIAGRDVCTADISVKH-----PDTDEESDIDAV----DARPLESKPSKPKTEIPKP 4101 Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371 + L + VEG +V CR V WF +G+P+ + R+ +L Sbjct: 4102 EIVLGLRDRFVVEGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLT 4159 Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 + D+G+Y C+ +N G+A TS L V Sbjct: 4160 IKDCKLADAGIYKCEVSNVGGKAGTSAHLTV 4190 Score = 121 bits (292), Expect = 1e-26 Identities = 105/418 (25%), Positives = 177/418 (42%), Gaps = 28/418 (6%) Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 VE P + P +++QP E E + E G+P P I W ++ + + Sbjct: 2541 VEVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTY 2600 Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520 L IR V + D ++ A+N G+A SA L V E R+ R P Sbjct: 2601 FDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLE--REAR-----PRILEKL 2653 Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP-Q 4579 Q+V+ + G+ +V+G+ V W + +++ + +E Y L +E + Sbjct: 2654 QDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLTIEYIDYE 2713 Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 D G Y+ V IN +GE A L + +P EP+ EG Sbjct: 2714 DEGAYKAVVINDSGEVSSTA----VLRLAEGMIEPSFIGIE-----FEPI---TAYEGSD 2761 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 I+ + + G+PLPTV++ K + + S +++ + +TL +S+ D YK VA N Sbjct: 2762 IDLTFYVKGRPLPTVEFLKDEVPVFKSDRTELTSNGNRHTLYLSDLAVRDSATYKAVAKN 2821 Query: 4700 SAGRVTVAAKLKVTQP---DQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755 AG + +L V + P + L+ V EG + + ++T PTI+W Sbjct: 2822 KAGVARRSVELLVKPKRGLKPGEAAPEIVQRLKACEVPEGSSFKLRCRVTGTPTPTIEWY 2881 Query: 4756 REGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 + +P P+ ++I H G+ L T D G + A G V TSA+L+++ Sbjct: 2882 KSN--MPLKPNGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIE 2937 Score = 120 bits (290), Expect = 2e-26 Identities = 108/488 (22%), Positives = 204/488 (41%), Gaps = 42/488 (8%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 G P P ++W + L + K +R + + V++L + P D Y C A N+ G+A Sbjct: 227 GKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAK--PEDTALYKCEAENKLGKAS 284 Query: 157 CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216 + ++ + + E E K + + K T Sbjct: 285 RAFDVKVKAPKGDAPSFTIDLTHVRAIEGEESKLVCKVTGKPAPTIEWLKGELPVTTSLR 344 Query: 217 STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEID--RSLGPVSPPKIAQKPRN 274 DF+ + ++++ ++ T + V +D + I + + P+I R+ Sbjct: 345 VRTDFEKNVATL-VIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTKPEIEDSLRD 403 Query: 275 SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--TLRVRNTQKSD 332 G +F+V++ G P+P+V W K G+ +I + I + +L +++ +++D Sbjct: 404 VSALPGERVKFKVRIGGKPKPKVEWRK-GKSVIEDGERFTIAEESDEVFSLIIQDLEETD 462 Query: 333 SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392 +G Y C+ T+ + + E+ ++ ++E+ + P Sbjct: 463 AGRYK--------CVATN----------------------EAGEAESMAQLTVNEELIGP 492 Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM- 451 +F K+ + V EG+ RVTG+P PE+ W + + +R N + E + A++ Sbjct: 493 RFEKMKESFTVVEGESVELVARVTGKPAPEIEWTKDGKTVRKTNN--VDTKERDDQAVLT 550 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE-QVVAPKFVERFSTLNVREGEPVVL 510 I + DSG+ C ARNKSG +L+V K+ + AP+ V + EG+ VL Sbjct: 551 IEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAVL 610 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 + G P P I W K+G+ + + + G L I +A D Y C +N G Sbjct: 611 SCTISGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELG 670 Query: 571 STATRARL 578 S ++ +L Sbjct: 671 SAESKTKL 678 Score = 120 bits (289), Expect = 3e-26 Identities = 119/523 (22%), Positives = 205/523 (39%), Gaps = 48/523 (9%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 +PGE +P I +++ K +G + K ++ G PTP + W + PL + + + Sbjct: 2841 KPGEAAPEIVQRL-KACEVPEGSSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGH-- 2897 Query: 125 QTGDVSLL-IKQIGPGDEGEYTCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRH 181 TGD L + DEG Y A+N G S + I+P Sbjct: 2898 -TGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVSPPSFRHRLTAVEVDE 2956 Query: 182 VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241 ET + + E ++ Q++ +T+G H + + + ++ ++ Sbjct: 2957 GDETRFDVRLKKEPTSVEWYKEQQRI-FTDG--HFEVIEGEEECLYSLVISNTKVADAGG 3013 Query: 242 KRYVGESDV-QISTEIDRSLGP-VSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVT 298 + ++ + ST + + + PP S +LQEG + GNP P + Sbjct: 3014 YKCTALNESGKSSTRAELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVKGNPYPEIR 3073 Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 W+K+ + S K + +L + + DSG Y + +N G + Sbjct: 3074 WYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVG-----------TA 3122 Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418 T+S+ D ++ K + P+F + + + +G RF+C+V+G Sbjct: 3123 TKSFTVDVEAK----------------KSKGIIPEFFRQLRRVEAVQGSTARFECKVSGH 3166 Query: 419 PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478 P P++ W + +++ K + L D G TCVA N++GE + Sbjct: 3167 PEPQIAWLKDGKELAIPRYIKPFY-DGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHA 3225 Query: 479 RLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538 L V+ K +V P+F ER + V EG+ + R G P P++ W K G I R Sbjct: 3226 SL-VLSKP-LVMPEFKERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKKI--KSHAR 3281 Query: 539 IHTDGGAS---TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + G TL I D Y+C A N AG RL Sbjct: 3282 FSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRL 3324 Score = 120 bits (288), Expect = 4e-26 Identities = 115/511 (22%), Positives = 208/511 (40%), Gaps = 43/511 (8%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 S PIF+Q K +G + +FE KL P P V W + + + + ++++ E +G Sbjct: 1468 SRPIFQQKLKAVSTIEGESTRFEVKLSAMPRPTVEWFKSSSQIYDGGRFTITEEENSGVY 1527 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE----T 185 L+I+ D G Y A N G+ ++ +E Sbjct: 1528 VLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEKTEGDDLE 1587 Query: 186 VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245 + + G E + + + ++ + S D+ T L + + + + Sbjct: 1588 LTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKA 1647 Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 G S + ++ + + P I + +++EG + +SG P P + W+K+G R Sbjct: 1648 GSSSRTFNLDVQKKKVIGNAPDIITHLISKEVKEGGTVTLECTVSGKPAPNIEWYKDGLR 1707 Query: 306 LINSNKHEIITTHNHTTLRVRNT--QKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-SY 362 + + ++TT + + V T Q D G Y +A NP G +S L V P++ + Sbjct: 1708 FTATRR--VMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSKPEF 1765 Query: 363 VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422 Q R + + + + + RI+ K + + D ++T PY Sbjct: 1766 KQKLRPLEVVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQIT--------EPYE- 1816 Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 DD I++N + A M CVA N++G+T + L V Sbjct: 1817 ----------GDDTYSLIILNTTMEDAAM-----------YKCVAFNEAGKTTCRADLTV 1855 Query: 483 IEKEQVVAPKFV--ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH 540 IEK+Q P F+ + T+ V+EG+ + ++A G P+P ++W KDG ++ + + Sbjct: 1856 IEKQQ--PPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQETR 1913 Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 G S L + AK DA Y+C A N G+ Sbjct: 1914 KRGDESHLVVFNAKMEDAGSYKCEANNKLGT 1944 Score = 120 bits (288), Expect = 4e-26 Identities = 175/788 (22%), Positives = 305/788 (38%), Gaps = 76/788 (9%) Query: 1959 EDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGR 2018 E SR + + + +P F + + + EG + +P V+W+ R Sbjct: 4498 ETASRADQTPDEPTAESGEPVFVQKPETCRLKEGDTARFNVKVNGSPEPF--VDWFLGRR 4555 Query: 2019 PVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYL 2077 +++ R + D G +L I+ ED G Y C A N G + + VD + L Sbjct: 4556 MIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEED-EL 4614 Query: 2078 DT----LDEQRLKKIQELEKYERPKPIEEEQ-PGQRPVFLTALTSLENLKEGDRAHFECR 2132 D ++ + + E KP + E P +PVF + L + +KEG+ + + Sbjct: 4615 DAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELID-KQVKEGENLSLDVK 4673 Query: 2133 VEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE 2192 + + + W+ + +K+ HR L I +D Y ATN G Sbjct: 4674 LP--QEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASG- 4730 Query: 2193 AVNTCTLKVAGHRNIILDTQHPNGLEKIRQL-EAQGHSTRIEVEEPKISPPRFVTELRGT 2251 +C +V I K+ Q+ +G S +V P F+ + + T Sbjct: 4731 -TTSCDCEVLVEERI-----------KVPQIANIRGGSRLSQVA------PEFMEQCKST 4772 Query: 2252 THVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPED 2311 T V E TA E V L I ++ N + ++ R ++ D + +L I +D Sbjct: 4773 T-VQENGTAIME--VRATGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKD 4829 Query: 2312 AGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPV 2371 G Y N G +TV ++S+ + +G + P R P+ Sbjct: 4830 EGLYMCVISNKAGTADCEALLTVEP---MVSDGE--DGAT-----HGSPPKTRGTKPKKS 4879 Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431 + +P PL N++ + G + +I + K+EWF++ +LI D R T T + Sbjct: 4880 SGAKPSIVTPLANME-VFSGDDVMLE--VISGPEQVKKIEWFKDNELIRDRPRFTVTSED 4936 Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLE 2491 ++TI+ +DEG++ C N G E+ E + ++E Sbjct: 4937 TRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIE 4996 Query: 2492 QPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVEL 2551 + RRS + E F Q L E+ +G H++ R+ G P + WY + EL Sbjct: 4997 R---RRSRDSICALE---FQQELKD-REVLDGDTIHFDVRIT--GRPEPKVVWYKDDKEL 5047 Query: 2552 KMGSR--FRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQ 2609 R F + + G +L I +D G Y C A N AG +++ Sbjct: 5048 VESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAG-------TISCQAELLVED 5100 Query: 2610 AMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPR 2669 PE + K A P+ ++AP+FT LK + +G +A+V Sbjct: 5101 V--PEEEDTTDSKPAPAT-APK--PAKRKEEAPVFTALLKD-RTIKDGDAARFDARVIGF 5154 Query: 2670 TDPNLKIEWFKNGVTLTTGA--RLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAV 2727 P+ + W + +T + +K+ + + +L I DSG+Y C A N G+ Sbjct: 5155 PTPD--VTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDT 5212 Query: 2728 STASIKIE 2735 + + +E Sbjct: 5213 TVGHLFVE 5220 Score = 119 bits (287), Expect = 5e-26 Identities = 171/805 (21%), Positives = 303/805 (37%), Gaps = 79/805 (9%) Query: 1278 DTQNEQAIEQIQLLEDAARRTKQVREDITVMQA-PQFSRALHNIETVEGTNVHLECRLQP 1336 D ++ +E+ LL + A R Q ++ T P F + EG ++ Sbjct: 4483 DEPAKEPVEEEALLPETASRADQTPDEPTAESGEPVFVQKPETCRLKEGDTARFNVKVN- 4541 Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFR-PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395 G V+WF + I+ R R + +L ++ + ED+GVY C A N G Sbjct: 4542 -GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSIS 4600 Query: 1396 TSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESV---TIKPRFVTRPKS 1452 L V ++D + P+ +E E T +T++ S P+ V + Sbjct: 4601 CEAELIVDIEEDEL--DAEPTEVEPAP-AEPTPTKIQTEVSKPSKREPAPAPKPVFASEL 4657 Query: 1453 IENVI-EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511 I+ + EG+++ + KL + +V W+++ + + HR I L I + Sbjct: 4658 IDKQVKEGENLSLDVKLPQ--EYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSI 4715 Query: 1512 EDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVD 1571 +D +Y A N GT C + + + G QV Sbjct: 4716 KDEAVYKVVATNASGTTSCDCEVLVEERIKVPQIANIRGGSRLSQV-------------- 4761 Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631 AP K+ ++E A E R L + W+ N + +K G R +++ Sbjct: 4762 -----APEFMEQCKSTTVQENGTAIMEVR--ATGSQPLSIRWFKNQQTIKYGGRIKMSSD 4814 Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691 L I +D G Y C N G A + V S + G+ P+ Sbjct: 4815 GEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPPK---T 4871 Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751 T + A+ ++T P+ ++ V E +I + ++EW ++ Sbjct: 4872 RGTKPKKSSGAKPSIVT-------PLANMEVFSGDDVMLE--VISGPEQVKKIEWFKDNE 4922 Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLE 1811 I R T + L + +D G + C +N+ G A S+ + V+ E Sbjct: 4923 LIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSE 4982 Query: 1812 SQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPY 1871 S + A + ++E R + R+ + A F +L ++ +G + H++ RI Sbjct: 4983 SSADEATDRNARIE---RRRSRDSI-----CALEFQQELK-DREVLDGDTIHFDVRITGR 5033 Query: 1872 PDPNMRVEWYFNGKVLQSGHR--YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929 P+P +V WY + K L R + + + G +L I +D G+Y C A N G Sbjct: 5034 PEP--KVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTIS 5091 Query: 1930 SSIRLNVQS--KESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNA 1987 L V+ +E DS+ A + K A + + E P F +K+ Sbjct: 5092 CQAELLVEDVPEEEDTTDSKPAPA----------TAPKPAKRKE----EAPVFTALLKDR 5137 Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV-QQGH-RFKTTYDFGYVALDILYAYAE 2045 + +G +A + + PT V W + + H K ++ +L I + Sbjct: 5138 TIKDGDAARFDARV--IGFPTPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYK 5195 Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVD 2070 D+G Y C A N+ G+ T + V+ Sbjct: 5196 DSGVYKCIAKNSAGQDTTVGHLFVE 5220 Score = 119 bits (286), Expect = 7e-26 Identities = 89/318 (27%), Positives = 144/318 (45%), Gaps = 33/318 (10%) Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323 S P QK + EG +F+V+LS PRP V WFK+ ++ + + I Sbjct: 1468 SRPIFQQKLKAVSTIEGESTRFEVKLSAMPRPTVEWFKSSSQIYDGGRFTI--------- 1518 Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383 T++ +SG Y L+ E+ N I +G T V +T ++ + Sbjct: 1519 ----TEEENSGVYVLVIEDTN--IEDAG-------TYKVVAYNNLGKVT------SQALL 1559 Query: 384 EISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 ++E P+F+ + + TEG RV G+P PE+ WF DR + Sbjct: 1560 RVNEVLTVPEFMDKAEGPIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKS 1619 Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVERFSTL 500 ++ + ++++ L DSG+ CVARNK+G ++ L+V +K++V+ AP + + Sbjct: 1620 RDN-KFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDV-QKKKVIGNAPDIITHLISK 1677 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 V+EG V L G P P I W KDG+ + DG +++ A+ D Sbjct: 1678 EVKEGGTVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGE 1737 Query: 561 YQCTAQNVAGSTATRARL 578 Y+C A N GS + ARL Sbjct: 1738 YKCVATNPLGSAQSSARL 1755 Score = 117 bits (282), Expect = 2e-25 Identities = 139/561 (24%), Positives = 220/561 (39%), Gaps = 67/561 (11%) Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627 +M E +P + LKN E+ EG A E R+ V +V WY +N+PL ++ Sbjct: 3969 EMEPEFEGISPRFSVKLKNQEVIEGSTARLECRI--VGSPVPEVRWYRDNEPLIESEKYQ 4026 Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAV-TSGIAIVHSKKSIYLESQHEGALP 1686 + AL + ED G Y A N G V T+ I++ H ++ E + Sbjct: 4027 MEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHP------DTDEESDID 4080 Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746 + D + ++ + P + ++D V E + F R PK V W Sbjct: 4081 AV----DARPLESKPSKPKTEIPKPEIVLGLRDRFVVEGMSVRFNCRT--TSQPKPYVTW 4134 Query: 1747 LRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806 ++G P+ + R G +L +K D+G Y C N G+A TS+ L Sbjct: 4135 FKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHL------ 4188 Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866 +++L S R V V PRF +L G + G + Sbjct: 4189 -------------TVEELPKS-----RPSV---VASPPRFQEELKGVITVV-GTTTKLSV 4226 Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND----FGFAALDILTVYGEDSGEYTCKAI 1922 I +P P +EWY + + + G R R D F +L I V D G Y C A Sbjct: 4227 PIIGHPTPV--IEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAK 4284 Query: 1923 NNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS-RYKRAVQDDSFVV---EKP 1978 N G SS + V KE DS E A+ + D++ R + S + E P Sbjct: 4285 NKSGTDFSSATVKV--KELDDEDSIQEGAMSLPKSTSDEALRMEDIPVAQSTPLKRGEPP 4342 Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038 +F + +++ + E + DPT EW +P+ G R+ D L+ Sbjct: 4343 EFIRKLRDQFIQEKETARFVCRVIGRPDPTY--EWLRGDKPITDGGRYTIMSDDEGQTLE 4400 Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA----------KSGLYLDTLDEQRLKKI 2088 I ED G Y C +TN+ G TT+ + V+A K + ++DE+ + + Sbjct: 4401 ITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPISKNIEKLLIKAASMDEESMSQA 4460 Query: 2089 QELEKYERPKPIEEEQPGQRP 2109 E P+ + E +P +P Sbjct: 4461 LAKAIAESPELLGEPEPESKP 4481 Score = 117 bits (282), Expect = 2e-25 Identities = 177/772 (22%), Positives = 302/772 (39%), Gaps = 100/772 (12%) Query: 3407 RKDTSVEEEKGKA--PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLK 3464 R D + +E ++ PVF V L+EG+ A F ++ + +P V+W+ + ++ Sbjct: 4502 RADQTPDEPTAESGEPVF-VQKPETCRLKEGDTARFNVKVNGSPEPF--VDWFLGRRMIE 4558 Query: 3465 AGSRFRTF-CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523 R R D G L I ED+G Y C A N+ G A + V I E + Sbjct: 4559 EDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVD-----IEEDE 4613 Query: 3524 LPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP-----PEFTTTPSDLILSENSSAHFE 3578 L E T + A E + T + P P F + D + E + + Sbjct: 4614 LDA--EPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLD 4671 Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638 +L + V W+ + K L R+ I L I GV +D +Y ATN Sbjct: 4672 VKL--PQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNAS 4729 Query: 3639 GEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFT 3698 G + C++ V+ R I PQ+ ++ + G+ Q E + + + T++ Sbjct: 4730 GTTSCDCEVLVEER---IKVPQI-ANIRGGSRLSQVAPEFMEQCKSTTVQ---------- 4775 Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDID 3758 E G + R G + I WF N + G R+ +D L I Sbjct: 4776 ----------ENGTAIMEVRA--TGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKIS 4823 Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISD 3818 + +D G Y C +NK G+A A +T +E + G G + R Sbjct: 4824 PVEKKDEGLYMCVISNKAGTADCEALLT--------VEPMVSDGEDGATHGSPPKTR-GT 4874 Query: 3819 APKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878 PK+ P +T + + V + V E P++ K IEW+++ +L+ R+ Sbjct: 4875 KPKKSS--GAKPSIVTPLANMEVFSGDDVMLEVISGPEQVKK--IEWFKDNELIRDRPRF 4930 Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938 + +L I +D G + C +NDFG A I ++ +++ Sbjct: 4931 TVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEI-------LVEEDEESYSES 4983 Query: 3939 RSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLA 3998 ++ T A I++ S D + ++ +Q + +++ +T F+ ++ Sbjct: 4984 SADEATDRNARIERRRSR-----DSICALEFQQELK-------DREVLDGDTIHFDVRIT 5031 Query: 3999 PVGDPNMKVEWFFNGKPLLHKNR--FTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGM 4056 G P KV W+ + K L+ R F + G ++ +D G+Y C A N G Sbjct: 5032 --GRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGT 5089 Query: 4057 DETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSL 4116 +A + +V D +P+ E + + + P+ + +A PVF +L Sbjct: 5090 ISCQAEL-------LVED--VPEE----EDTTDSKPAPATAPKPAKRKEEA---PVFTAL 5133 Query: 4117 PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS--RYKLTYDGMYH 4166 T+++G+ ARF RV G P P V WL I S K ++G H Sbjct: 5134 LKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALHEGEVH 5185 Score = 117 bits (281), Expect = 3e-25 Identities = 112/515 (21%), Positives = 202/515 (39%), Gaps = 42/515 (8%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P FE++ ++ +G + + ++ G P P + WT+ + + N + E+ L Sbjct: 492 PRFEKMKESFTVVEGESVELVARVTGKPAPEIEWTKDGKTVRKTNNVDTK--ERDDQAVL 549 Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191 I++ D G Y CTARN+ G A + + + R V T A Sbjct: 550 TIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAV 609 Query: 192 ------GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245 G T E + +V + T D T + + I + + Sbjct: 610 LSCTISGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNEL 669 Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 G ++ + ++ + P+ K + K EG + Q V++ G P+P + W++ Sbjct: 670 GSAESKTKLKVIA----FARPEFRTKLKPVKAVEGEEVQLDVKVEGYPKPDIEWYRGTTM 725 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365 ++ S + +++ ++ + G Y+L+ + +G + V + S Sbjct: 726 IVESGRFKVME------------EEEEDGLYSLVISKLQ--LDDTGTIKVVATNASGKAT 771 Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDV-TEGKMTRFDCRVTGRPYPEVT 424 R+ +E+ E+ AP+F + V TEG RV P +V Sbjct: 772 SRAD-------------LEVKEREFAPEFEGDEEGPIVVTEGNEVSIQLRVKANPNADVD 818 Query: 425 WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-I 483 WF + R I + I H L I +L D+GV C A N+ G+ + + V + Sbjct: 819 WFKDGRPIYESTKRDIK-RRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQV 877 Query: 484 EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543 + + AP + + + EGE L G P P W +DG+ I + ++I T Sbjct: 878 KGPKGEAPIILSKLRPVETEEGEETKLKCTFTGKPAPTCEWTRDGIRIRSSRMVQIDTTE 937 Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 +STL I D Y+CT +N G+ +T A + Sbjct: 938 DSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEV 972 Score = 116 bits (280), Expect = 4e-25 Identities = 83/288 (28%), Positives = 134/288 (46%), Gaps = 21/288 (7%) Query: 197 TTEQSRQTQKVAYTNGTDHSS-----TDDFKVDTFEYRLLREVSFRESITKRYVGES-DV 250 T+E +R T +A D +DF + + +L E ES ++ E+ D Sbjct: 4933 TSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEED-EESYSESSADEATDR 4991 Query: 251 QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310 E RS + + Q+ ++ ++ +G F V+++G P P+V W+K+ + L+ S Sbjct: 4992 NARIERRRSRDSICALEFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVES- 5050 Query: 311 KHEIITTHNHT---TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES-PTESYVQDQ 366 K I + T +L ++ D G Y +A NP G I L VE P E D Sbjct: 5051 KRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEEDTTDS 5110 Query: 367 RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426 + T + + +E AP F + +DR + +G RFD RV G P P+VTW Sbjct: 5111 KPAPATAPKPAKRKEE--------APVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWL 5162 Query: 427 INDRQIR-DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473 D+QI + + H ++E H+L+IT DSGV C+A+N +G+ Sbjct: 5163 REDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQ 5210 Score = 113 bits (273), Expect = 2e-24 Identities = 192/774 (24%), Positives = 308/774 (39%), Gaps = 108/774 (13%) Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047 EV EG P+ L + PT VEW+ R ++ K + L I A ED+ Sbjct: 3637 EVWEGAPIKLIVQIKGKPAPT--VEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDS 3694 Query: 2048 GTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQ 2107 G Y C+ATN G T V V+ EQ++ R +PI PG Sbjct: 3695 GNYRCQATNDAGTVTKTFKVVVN-----------EQKVVM--------RRQPIP---PGA 3732 Query: 2108 -RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTT-HDFG 2165 +P FL + LE + EG A RV+ + +P IDW+ + + IR G R + G Sbjct: 3733 VKPSFLQRMQDLE-IVEGSAARLCVRVQGVPEPE--IDWYKDNRVIREGGRVEFEFEEDG 3789 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGH------RNIILD-TQHPNGLE 2218 L I D G Y C +N G+A + L + H + LD E Sbjct: 3790 LCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARE 3849 Query: 2219 KIRQLEAQGHSTRIEVE-EPKI--SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLR 2275 +L + S + E PK +PP F LR V EG F +V + ++ Sbjct: 3850 STIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNR-EVKEGGVTKFASRV--ISKAPIK 3906 Query: 2276 IEFYHNGKALQSA-ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 +E+Y + + + S R D +++I + D G Y+ N G TV Sbjct: 3907 VEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYG--------TV 3958 Query: 2335 TAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTA 2394 +K L + E+E PE E ++ P F+ L+N + I EG TA Sbjct: 3959 ESKAY----------LNVLPEME-------PEF-EGIS---PRFSVKLKNQEVI-EGSTA 3996 Query: 2395 HFDCRLIPVGDPTLKVEWFR-NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453 +CR+ VG P +V W+R NE LIE S + D + ++ + V +ED+G Y A Sbjct: 3997 RLECRI--VGSPVPEVRWYRDNEPLIE-SEKYQMEQDGDHFALIVKDVSEEDDGHYKAVA 4053 Query: 2454 SNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKK--IQKLE-QPHERRSEEPDREFEKPIF 2510 N+ G + +HP+ ++ I ++ +P E + +P E KP Sbjct: 4054 RNIAGRDVCTA----------DISVKHPDTDEESDIDAVDARPLESKPSKPKTEIPKP-- 4101 Query: 2511 TQVLTGPSELW--EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTL 2568 +++ G + + EG + R P W+ +G L R+ T G +L Sbjct: 4102 -EIVLGLRDRFVVEGMSVRFNCRT--TSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSL 4158 Query: 2569 DINSVVANDAGLYMCKAIN---RAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAA 2625 I DAG+Y C+ N +AG + A P E+++ Sbjct: 4159 TIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPSV-VASPPRFQEELKGVITV 4217 Query: 2626 MNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPR-TDPNLKIEWFK--NG 2682 + ++ V P+ + K +++EG + E E R T +L I + + Sbjct: 4218 VGTTTKLSVPIIGHPTPVIEWY-KDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDE 4276 Query: 2683 VTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 A+ KS DF T+ + L ++DS + L ++ S ++++ED Sbjct: 4277 GRYKCVAKNKSGTDFSSATVKVKELDDEDS---IQEGAMSLPKSTSDEALRMED 4327 Score = 113 bits (273), Expect = 2e-24 Identities = 194/848 (22%), Positives = 321/848 (37%), Gaps = 102/848 (12%) Query: 2608 DQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVE 2667 D+ + E+ L E A T P+F ++ +L EG +V Sbjct: 4483 DEPAKEPVEEEALLPETASRADQTPDEPTAESGEPVFVQKPETC-RLKEGDTARFNVKVN 4541 Query: 2668 PRTDPNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726 +P ++WF + R++ D G +L I + +D+G+Y C A N G Sbjct: 4542 GSPEPF--VDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSI 4599 Query: 2727 VSTASIKI---EDRHWLLGESLHPDSLDRIGA-LXXXXXXXXXXXXXXXXXXVFISHLNN 2782 A + + ED + P + + VF S L + Sbjct: 4600 SCEAELIVDIEEDELDAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELID 4659 Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 KEG+N+ + V+ ++ ++ W+ ++K L R L I +D Sbjct: 4660 KQVKEGENLSLD--VKLPQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKD 4717 Query: 2843 SGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPS 2902 +Y ATN+ G TTS C D + + E ++ + A + G R S Sbjct: 4718 EAVYKVVATNASG--TTS----C--DCEVLVE----------ERIKVPQIANIRGGSRLS 4759 Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962 PE++ + G + +V L I W+ N + ++ G R K+ Sbjct: 4760 -----QVAPEFMEQCKSTTVQENGTAIM---EVRATGSQPLSIRWFKNQQTIKYGGRIKM 4811 Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022 +SD TL + V ++D G+Y C NK G A + + T P ++G Sbjct: 4812 SSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALL-----------TVEPMVSDGE 4860 Query: 3023 EKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVI 3082 + + S K G +P +G P T ++ ++ G E +I +Q I Sbjct: 4861 DGATH--GSPPKTRGTKPKKSSGAKPSIVTPLANM-EVFSGDDVMLE--VISGPEQVKKI 4915 Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL---- 3138 EWF + + I R L I D G + C N +G A S ++ Sbjct: 4916 EWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEE 4975 Query: 3139 -----------ECVDKSKGQKPR----------FTTHIQNIEGLKDGQSAHFECTVVPVD 3177 E D++ + R F +++ E L DG + HF+ + Sbjct: 4976 DEESYSESSADEATDRNARIERRRSRDSICALEFQQELKDREVL-DGDTIHFDVRIT--G 5032 Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235 P+ K+ WY + + + S RI VS+ G L I D G+Y C A N G Sbjct: 5033 RPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAG---- 5088 Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQG-AQQQTPSTPSAEPPKFITQIQDVTKL 3294 TI+C E L D + +S A P+ E P F ++D T + Sbjct: 5089 --TISCQA------ELLVEDVPEEEDTTDSKPAPATAPKPAKRKEEAPVFTALLKDRT-I 5139 Query: 3295 VEGQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGHRY-RTFHDFGIVILDILYCYEENS 3352 +G +A F+AR++ PD V W K++ P+ H + + H+ + L I ++S Sbjct: 5140 KDGDAARFDARVIGFPTPD--VTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYKDS 5197 Query: 3353 GEYECVATNKLGRDSTKANLKCTSKE-NLILDSQLPRGMEGGLEKL-QTLEDSMVRRKDT 3410 G Y+C+A N G+D+T +L E I Q P GL ++ + L + Sbjct: 5198 GVYKCIAKNSAGQDTTVGHLFVEGPEFKPIKGVQKPERKSSGLARIEEVLTLKLYTATSD 5257 Query: 3411 SVEEEKGK 3418 + EE GK Sbjct: 5258 FLSEETGK 5265 Score = 113 bits (272), Expect = 3e-24 Identities = 118/522 (22%), Positives = 197/522 (37%), Gaps = 45/522 (8%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 RP P I + K+ +G A+ E + G PTP + W R + E + +R Sbjct: 2251 RPEGTEPNIVSGL-KSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRR--VRSTL 2307 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI------QPEGXXXXXXXXXXXXX 178 + G L+I + D G Y C RN G S ++ +PE Sbjct: 2308 ENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGD 2367 Query: 179 YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE 238 V+ Y + +R + + T + + E + + + Sbjct: 2368 RAKFEVRVKGYPYPEVEWYHGSNRILDEDRF-EIESVKETGYYSLTVGEV-VQEDAGMYK 2425 Query: 239 SITKRYVGESDVQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297 I G+S + E+ +R P + P + EG + +V L NP+P+V Sbjct: 2426 CIAVNKAGKSTCRADLEVNERQFAPEFETGEERGP--IVVPEGGETTLKVTLRANPKPQV 2483 Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 W+K+G+ + + ++ + N L++ N + DSG Y A N G S + VE Sbjct: 2484 IWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADKSFTIRVEV 2543 Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417 P + T E I ++ Q D EG+ + +CRV+G Sbjct: 2544 P------------------KPTGEEPTILQR---------LQPVDTIEGEAIKMECRVSG 2576 Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477 +P P +TW + D K + L I +V L D G+ C A+N SG Sbjct: 2577 KPEPTITWLKDGLVFLTDNRIKTYF-DGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSS 2635 Query: 478 CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537 L V+E+E P+ +E+ ++ GE + R G+P P + W + I Sbjct: 2636 AELTVLERE--ARPRILEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHY 2693 Query: 538 RIHTDG-GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + +G G +L I D Y+ N +G ++ A L Sbjct: 2694 IVRDEGRGYFSLTIEYIDYEDEGAYKAVVINDSGEVSSTAVL 2735 Score = 113 bits (271), Expect = 4e-24 Identities = 99/411 (24%), Positives = 169/411 (41%), Gaps = 39/411 (9%) Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463 P++ S P I TK ++ V E E E G P P ++W ++ ++ S + Sbjct: 1088 PIEGSAPKI-TKPLESVEVNEGEDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDG 1146 Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523 + L+ +Q ED + N G A + + V R P F + V Sbjct: 1147 NVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSR--------PEFKIKMSPV 1198 Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583 VT G + +V G + V W K K++ R + YT++I +D+G Sbjct: 1199 EVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGG 1258 Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643 Y CVA N+AG+ A+ V + P+ +T+ E+ + ++ K+ Sbjct: 1259 YRCVATNTAGKTTSRADLTVK--EREFAPEFETRDDTIDSEVNKEVEIKVTT-------- 1308 Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 G+P I+ S + D +T I A D G YKC A N+AG Sbjct: 1309 ----GEP------------IRDSINTDVRAIGDSHTCFIVRAKLSDAGVYKCQATNAAGS 1352 Query: 4704 VTVAAKLKVTQ--PDQADNLPALT-PLRDIVVYEGQPAQFKTQITS-KIKPTIQWLREGA 4759 + + ++KV Q P P + L+ + EG A ++T+ K +P+I+W R+G Sbjct: 1353 ASRSWEVKVKQSAPKTTGEEPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGV 1412 Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 I E +M+ +G L I + +D G + T G ++ +++V Sbjct: 1413 KIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLV 1463 Score = 111 bits (266), Expect = 2e-23 Identities = 127/505 (25%), Positives = 203/505 (40%), Gaps = 46/505 (9%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +GG + LR NP P V W + E + +R T + + +I D G Y Sbjct: 2465 EGGETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIE--DSGSY 2522 Query: 145 TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204 C ARN+ G A S I+ E + V +T+E +A + + + T Sbjct: 2523 KCEARNKLGFADKSFTIRVEVPKPTGEEPTILQRLQPV-DTIEGEAIKMECRVSGKPEPT 2581 Query: 205 ---QKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFR-ESITKRYVGESDVQISTEIDRS- 259 K TD+ F D + R+V E I + S + + + Sbjct: 2582 ITWLKDGLVFLTDNRIKTYFDGDVCTLTI-RDVKLGDEGIYRCNAKNSSGSAHSSAELTV 2640 Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319 L + P+I +K ++ G A F++++SG+P P V W++ + E ITT Sbjct: 2641 LEREARPRILEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYR---------RDEEITTKG 2691 Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRET 379 H +R G+++L E Y+ E +Y ++ I D+ + + Sbjct: 2692 HYIVR-----DEGRGYFSLTIE----------YIDYEDEG-AY----KAVVINDSGEVSS 2731 Query: 380 EERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437 + ++E + P F+ + + +T EG V GRP P V F+ D + Sbjct: 2732 TAVLRLAEGMIEPSFIGI-EFEPITAYEGSDIDLTFYVKGRPLPTVE-FLKDEVPVFKSD 2789 Query: 438 HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV----VAPKF 493 L + H L ++++ + DS VA+NK+G L V K + AP+ Sbjct: 2790 RTELTSNGNRHTLYLSDLAVRDSATYKAVAKNKAGVARRSVELLVKPKRGLKPGEAAPEI 2849 Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553 V+R V EG L R GTPTP I W K +P+ PN + I G L+ Sbjct: 2850 VQRLKACEVPEGSSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLET 2909 Query: 554 KASDAAWYQCTAQNVAGSTATRARL 578 +A D Y A+N GS +T A L Sbjct: 2910 EARDEGRYMLVAKNHLGSVSTSAEL 2934 Score = 110 bits (265), Expect = 2e-23 Identities = 173/779 (22%), Positives = 286/779 (36%), Gaps = 81/779 (10%) Query: 627 PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686 P E P F+ ++ EG F ++ G P ++W + IE R Sbjct: 4507 PDEPTAESGEPVFVQKPETCRLKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIR 4564 Query: 687 -SIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745 G SL ++ ++ +D+G Y C A + G +A L V + P ++ Sbjct: 4565 IEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEE--DELDAEPTEVE 4622 Query: 746 YIQQLEDYSKYQHQESI----EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPT 801 +K Q + S E + +P F L D +++EG N + +L + Sbjct: 4623 PAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDK-QVKEGENLSLDVKLP--QEYK 4679 Query: 802 MRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIR 861 V WY+D + + RIT I L I + +D Y V A N G + Sbjct: 4680 AEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVL 4739 Query: 862 VAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISI 921 V R V I R S PEF K ++ Sbjct: 4740 VEERIKVPQIANIRGGSRL------------------------SQVAPEFMEQCKST-TV 4774 Query: 922 KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981 +E G A E R G L + W K+ + ++ RI + + L I V D G Sbjct: 4775 QENGTAIMEVRAT--GSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGL 4832 Query: 982 YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041 Y C N G A A LT+ + ++++ + + ++ T+ + Sbjct: 4833 YMCVISNKAGTADCEALLTV---EPMVSDGEDGA-------THGSPPKTRGTKPKKSSGA 4882 Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101 KP + PL ++ G E P+ +EW+ + + I R + Sbjct: 4883 KPSIVTPLANM-EVFSGDDVMLEVISGPEQ--VKKIEWFKDNELIRDRPRFTVTSEDTRH 4939 Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161 L IA+ +D G++ V N G A SA + VE + S ++ IE + Sbjct: 4940 TLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIERRR 4999 Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221 + + +E F Q L + V +G IH + R+ G P +V W+ + + + Sbjct: 5000 SRDSICALE--------FQQELKDRE-VLDGDTIHFDVRIT--GRPEPKVVWYKDDKELV 5048 Query: 1222 VGSR--FKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDT 1279 R F + + G +L I AT D G+Y A N G+ A + +V D Sbjct: 5049 ESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAEL-------LVEDV 5101 Query: 1280 QNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGD 1339 E+ + A + + +E+ AP F+ L + +G + R+ +G Sbjct: 5102 PEEEDTTDSKPAPATAPKPAKRKEE-----APVFTALLKDRTIKDGDAARFDARV--IGF 5154 Query: 1340 QTMRVEWFCNGKPIK-TGH-RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396 T V W K I H + +E + +L + +DSGVY C A N G+ T Sbjct: 5155 PTPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTT 5213 Score = 110 bits (264), Expect = 3e-23 Identities = 65/193 (33%), Positives = 99/193 (51%), Gaps = 5/193 (2%) Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441 ++ + E + P F QD DV EG +F V+G+P +V W D+++R+ + Sbjct: 3517 QLTVKEALIIPHFDHPIQDLDVIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLE 3576 Query: 442 VN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE--RFS 498 + E+ + L ITN +DSG TC+ARNK+GE RL V KE++V P F E Sbjct: 3577 EDRETQMYFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAV--KEKMVTPSFAEGDADE 3634 Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558 V EG P+ L + G P P + W K+ +++ T+G L IP+A+ D+ Sbjct: 3635 PCEVWEGAPIKLIVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDS 3694 Query: 559 AWYQCTAQNVAGS 571 Y+C A N AG+ Sbjct: 3695 GNYRCQATNDAGT 3707 Score = 109 bits (263), Expect = 4e-23 Identities = 180/808 (22%), Positives = 305/808 (37%), Gaps = 96/808 (11%) Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554 ++ +EP E +P+F Q L EG A + +V G P +W++ ++ Sbjct: 4504 DQTPDEPTAESGEPVFVQK-PETCRLKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEED 4560 Query: 2555 SRFRTTH-DFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQA--- 2610 R R D G +L I + DAG+Y C A N G +D Sbjct: 4561 DRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTE 4620 Query: 2611 MRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPR 2669 + P E K P + P+F + L DK V EG+++ L+ ++ P+ Sbjct: 4621 VEPAPAEPTPTKIQTEVSKPSKR-EPAPAPKPVFASEL--IDKQVKEGENLSLDVKL-PQ 4676 Query: 2670 TDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729 + ++ W+++ L R+ L L+I + D +Y ATN G Sbjct: 4677 -EYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCD 4735 Query: 2730 ASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGD 2789 + +E+R + P + G F+ + +E Sbjct: 4736 CEVLVEERIKV------PQIANIRGG-----------SRLSQVAPEFMEQCKSTTVQENG 4778 Query: 2790 NIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCK 2849 E S+ L I WF N + + G R K + D + +L I+ ++D G+Y C Sbjct: 4779 TAIMEVRATGSQP--LSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCV 4836 Query: 2850 ATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYP 2909 +N G+A L T P G + + +G +P + Sbjct: 4837 ISNKAGTADCEALL-----------TVEPMVSDGEDGATHGSPPK-TRGTKPK--KSSGA 4882 Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969 KP + P+ A ++ G + LE P+ KIEW+ + +++ RF +TS+ Sbjct: 4883 KPSIVTPL-ANMEVFSGDDVMLEVISGPEQVK--KIEWFKDNELIRDRPRFTVTSEDTRH 4939 Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLE 3029 TL + D GI+ C N G A S+ + + + + T+ +I+ Sbjct: 4940 TLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIE--- 4996 Query: 3030 DSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGK 3089 ++ D+ EF KD ++ +G H++ + TG + W+ + K Sbjct: 4997 --------RRRSRDSICALEFQQELKD-REVLDGDTIHFDVRI--TGRPEPKVVWYKDDK 5045 Query: 3090 TIEASHRIRTVY--AFGMVVLEILGTKTTDSGTYSCRATNKWG----QAEISV-----KL 3138 + S RI V G+ L I D G Y C A N G QAE+ V + Sbjct: 5046 ELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEE 5105 Query: 3139 ECVD------------KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWY 3186 + D K K + P FT +++ +KDG +A F+ V+ PD + W Sbjct: 5106 DTTDSKPAPATAPKPAKRKEEAPVFTALLKD-RTIKDGDAARFDARVIGFPTPD--VTWL 5162 Query: 3187 HNGQPMRHST--RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244 + + ++ +K + + L I DSG Y C A N G+D T + G Sbjct: 5163 REDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEGP 5222 Query: 3245 -----GGVYLESLQPDSLAKIRELESLQ 3267 GV + LA+I E+ +L+ Sbjct: 5223 EFKPIKGVQKPERKSSGLARIEEVLTLK 5250 Score = 108 bits (260), Expect = 9e-23 Identities = 82/312 (26%), Positives = 134/312 (42%), Gaps = 35/312 (11%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+I Q ++E +A +SG P P W+++ R+ S + + + TL + Sbjct: 9 PQILQPLEGVDVKEDENAILSCTISGTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTI 68 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 + T+ D G Y C++ R+++ T T + R+ + Sbjct: 69 KQTRAEDQGEYK--------CVL------------------RNEHGTATSKAPLNVRVPV 102 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 P F + D EG+ RFD V G P P+V W+ I +I+ Sbjct: 103 K-----PSFTSKMKPVDAEEGQEVRFDVHVKGSPKPDVVWYKGSTMIGTHERFQIVEAAE 157 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVRE 504 + L+I+ V L D+ VA N G+ + L V KE+ AP+F+ E ++ Sbjct: 158 DHVTLVISEVKLEDAETYKVVATNDVGKVTSRADLRV--KERQFAPEFIDEERGPIDATT 215 Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 G+ V L G P P ITW K+G + + +L I + G + + + AK D A Y+C Sbjct: 216 GDEVTLTCSVSGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCE 275 Query: 565 AQNVAGSTATRA 576 A+N G A+RA Sbjct: 276 AENKLGK-ASRA 286 Score = 108 bits (260), Expect = 9e-23 Identities = 121/524 (23%), Positives = 209/524 (39%), Gaps = 47/524 (8%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 +P P I +++ + +G K E ++ G P P ++W + + N+ ++ Sbjct: 2545 KPTGEEPTILQRL-QPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTYFD- 2602 Query: 125 QTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP-EGXXXXXXXXXXXXXYRHV 182 GDV +L I+ + GDEG Y C A+N G A S + E V Sbjct: 2603 --GDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLEREARPRILEKLQDVDSSV 2660 Query: 183 SETVEHK--AYGTQGYTTEQSRQTQKVAYTNG---TDHSSTDDFKVDTFEYRLLREVSFR 237 E K G+ + R+ +++ T G F + T EY + Sbjct: 2661 GERAMFKIRVSGSPMPVVQWYRRDEEIT-TKGHYIVRDEGRGYFSL-TIEYIDYEDEGAY 2718 Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297 +++ GE V + + + G + P I + EG+D + G P P V Sbjct: 2719 KAVVINDSGE--VSSTAVLRLAEGMIEPSFIGIEFEPITAYEGSDIDLTFYVKGRPLPTV 2776 Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 + K+ + S++ E+ + N TL + + DS Y +A+N G Sbjct: 2777 EFLKDEVPVFKSDRTELTSNGNRHTLYLSDLAVRDSATYKAVAKNKAG--------VARR 2828 Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417 E V+ +R + AP+ V+ + +V EG + CRVTG Sbjct: 2829 SVELLVKPKRG----------------LKPGEAAPEIVQRLKACEVPEGSSFKLRCRVTG 2872 Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAF 476 P P + W+ ++ ++ N ++++ +G+ + L D G VA+N G + Sbjct: 2873 TPTPTIEWYKSNMPLKP--NGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVST 2930 Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536 L +IE V P F R + + V EG+ + R PT + W K+ I + Sbjct: 2931 SAEL-IIE-PSVSPPSFRHRLTAVEVDEGDETRFDVRLKKEPT-SVEWYKEQQRIFTDGH 2987 Query: 537 LRI--HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + + +L I K +DA Y+CTA N +G ++TRA L Sbjct: 2988 FEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL 3031 Score = 107 bits (256), Expect = 3e-22 Identities = 142/511 (27%), Positives = 203/511 (39%), Gaps = 61/511 (11%) Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCD----FGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505 P +EWY + + + G R R D F V L I D G Y C A N G Sbjct: 4232 PTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDF 4291 Query: 3506 TTASMKVQ--GKRNIILES--QLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFT 3561 ++A++KV+ + I E LPK T D+ +E V TP + G PPEF Sbjct: 4292 SSATVKVKELDDEDSIQEGAMSLPKS---TSDEALRMEDIP--VAQSTP-LKRGEPPEFI 4345 Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621 D + E +A F CR+I D + EW KP+ G R ++D LEI Sbjct: 4346 RKLRDQFIQEKETARFVCRVIGRPDPT--YEWLRGDKPITDGGRYTIMSDDEGQTLEITD 4403 Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGII---LEPQLPSHFKSGTESI-QKLEE 3677 D GLY C +TN G T + +L V+ + I +E L ES+ Q L + Sbjct: 4404 CTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPISKNIEKLLIKAASMDEESMSQALAK 4463 Query: 3678 TLHKREEITIEDE---KP--NPPRFTVE--------------IKDNIDVPEGGPVHFD-- 3716 + + E+ E E KP P + VE D G PV Sbjct: 4464 AIAESPELLGEPEPESKPADEPAKEPVEEEALLPETASRADQTPDEPTAESGEPVFVQKP 4523 Query: 3717 --CRVEPVGDPTMRIDWFHNGRP-----FATGSRVHTLND--------FGFIALDIDYIY 3761 CR++ GD T R + NG P + G R+ +D G +L I I Sbjct: 4524 ETCRLKE-GD-TARFNVKVNGSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDID 4581 Query: 3762 ARDAGEYTCRATNKWGSATTTAKITCSAKRD-IVLESQLPQGMSGEKIKELERGRISDAP 3820 DAG Y C A N GS + A++ + D + E + E + +S Sbjct: 4582 REDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTEVEPAPAEPTPTKIQTEVSKPS 4641 Query: 3821 KEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880 K EP + P F +++ V+E E + + ++ P+E K + WYR+ K L HR Sbjct: 4642 KREPAPAPKPVFASELIDKQVKEGENLSLDVKL-PQE-YKAEVAWYRDDKKLEDDHRITI 4699 Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 + L I V +D Y A N G Sbjct: 4700 IAAGDLHCLTIFGVSIKDEAVYKVVATNASG 4730 Score = 105 bits (252), Expect = 9e-22 Identities = 110/504 (21%), Positives = 191/504 (37%), Gaps = 44/504 (8%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +GG E + G P P + W + + ++ V+ Q D+GEY Sbjct: 1681 EGGTVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQ--GFDDGEY 1738 Query: 145 TCTARNQYGEAICS----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQ 200 C A N G A S V + + V K+Y E Sbjct: 1739 KCVATNPLGSAQSSARLTVTVPSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKP--EVEW 1796 Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIST-EIDRS 259 R T K+ T+ H T+ ++ D ++ + ++ + V ++ +T D + Sbjct: 1797 YRGTTKI--TDSLRHQITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLT 1854 Query: 260 -LGPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316 + PP + +EG D ++G P P V+W+K+G+ +++S K E Sbjct: 1855 VIEKQQPPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQE--- 1911 Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376 ++ D H + N + +G SY + ++ T T+ Sbjct: 1912 ----------TRKRGDESHLVVF----NAKMEDAG---------SYKCEANNKLGTVTKT 1948 Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436 + + + + AP F +V EG + ++G P P V W + + +DY Sbjct: 1949 YNVKV-MSTAPEGQAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVKWTRDGIPVFEDY 2007 Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER 496 + + L+I NVT D GV C +N+ G T + VI ++ + P F ++ Sbjct: 2008 RISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTT--TTVQVIVTQRSIRPIFGQK 2065 Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-HTDGGASTLDIPRAKA 555 + R GE V + GTP P +T+ ++ I I + G L I + Sbjct: 2066 MKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRP 2125 Query: 556 SDAAWYQCTAQNVAGSTATRARLY 579 DA YQC A N AG ++ L+ Sbjct: 2126 EDAGEYQCIAVNGAGEVTSKGYLH 2149 Score = 105 bits (251), Expect = 1e-21 Identities = 147/624 (23%), Positives = 256/624 (41%), Gaps = 94/624 (15%) Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912 P ++ EG +I+ P P VEW+ + + + + L I E Sbjct: 3635 PCEVWEGAPIKLIVQIKGKPAPT--VEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPE 3692 Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDS 1972 DSG Y C+A N+ G + ++ V ++ ++R ++ + + Sbjct: 3693 DSGNYRCQATNDAGTVTKTFKVVVNEQKVVMR--------------------RQPIPPGA 3732 Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032 KP F + +++ E+ EG L + V +P ++WY + R +++G R + ++ Sbjct: 3733 V---KPSFLQRMQDLEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEE 3787 Query: 2033 -GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA---KSGLYLDTLDEQRLKKI 2088 G L I A D G Y C +NA G+A ++ + ++ SG+ LD K+ Sbjct: 3788 DGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEA 3847 Query: 2089 QE--LEKYERPKPIEE------EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPH 2140 +E +E EE ++ G P F L + E +KEG F RV I+ Sbjct: 3848 RESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNRE-VKEGGVTKFASRV--ISKAP 3904 Query: 2141 LTIDWFHNGQKIRAG-HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199 + ++W+ + + I + R+ HD A++I D G Y +NK G T+ Sbjct: 3905 IKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYG------TV 3958 Query: 2200 KVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKT 2259 + + N++ + + E +G S R V K+ + G+T Sbjct: 3959 ESKAYLNVLPEMEP----------EFEGISPRFSV---KLKNQEVI---EGST------- 3995 Query: 2260 AHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKA 2319 A EC++ V P + +Y + + L + ++ + D + +L ++ ED G Y A Sbjct: 3996 ARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVA 4053 Query: 2320 INALGH--CTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP--VTRQR 2375 N G CT+ IS+ K E + ++ R LES + EIP+P V R Sbjct: 4054 RNIAGRDVCTADISV----KHPDTDEESDIDAVD-ARPLESKPSKPKTEIPKPEIVLGLR 4108 Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 F + EG + F+CR P V WF++ + + R T G S Sbjct: 4109 DRF---------VVEGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQS 4157 Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459 +TI + D G+Y C SN+ G+ Sbjct: 4158 LTIKDCKLADAGIYKCEVSNVGGK 4181 Score = 103 bits (248), Expect = 3e-21 Identities = 128/507 (25%), Positives = 200/507 (39%), Gaps = 56/507 (11%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F+ KS T E G E R G + I W KN Q+I+ R + +L Sbjct: 4763 PEFMEQCKSTTVQENGTAIMEVRA--TGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTL 4820 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI-ERTSQHPETLQYIQQLEDYSK 755 + + +D G Y C + G A+ +A+L V P + E + H + Sbjct: 4821 KISPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPPK---------- 4870 Query: 756 YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815 ++ + +P + PL ++ E+ G + E P + ++EW+KD I Sbjct: 4871 -TRGTKPKKSSGAKPSIVTPLANM-EVFSGDDVMLEVISGP--EQVKKIEWFKDNELIRD 4926 Query: 816 SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875 R T +L I +D G + +N G A +A I V Sbjct: 4927 RPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEE----------- 4975 Query: 876 EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935 ++ Y E + +S EF+ +KD+ + +G HF+ R+ Sbjct: 4976 DEESYSESSADEATDRNARIERRRSR--DSICALEFQQELKDR-EVLDGDTIHFDVRIT- 5031 Query: 936 IGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993 G +V W KD + + S RI G +L IK T+ D G Y C A N G Sbjct: 5032 -GRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTI 5090 Query: 994 TTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTN 1053 + A L + +D+ E + A + +KR EE P F LK Sbjct: 5091 SCQAELLV---EDVPEEEDTT---DSKPAPATAPKPAKRKEEA------PVFTALLKDRT 5138 Query: 1054 KIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQIT--SANRIQTYHDFGYVALDIASVR 1109 I +G +A F+ARV P D+T W KQIT S ++ H+ +L I Sbjct: 5139 -IKDGDAARFDARVIGFPTPDVT----WLREDKQITPNSHPHMKALHEGEVHSLLITEGG 5193 Query: 1110 AEDSGVYTVVARNAAGEAQLSASMTVE 1136 +DSGVY +A+N+AG+ + VE Sbjct: 5194 YKDSGVYKCIAKNSAGQDTTVGHLFVE 5220 Score = 103 bits (246), Expect = 5e-21 Identities = 118/518 (22%), Positives = 201/518 (38%), Gaps = 48/518 (9%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRG-NPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PI + + +G A K+ P P + WTR + E ++ M ++ +T S Sbjct: 1373 PIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKIRENSRIKMVFDGET--CS 1430 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEA--ICSVYIQPEGXX-XXXXXXXXXXXYRHVSETVE 187 L I+ DEG Y T N+YG A C V + G S E Sbjct: 1431 LTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKLKAVSTIEGESTRFE 1490 Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247 K T E + + ++ Y G + T++ + ++ + + ++ T + V Sbjct: 1491 VKLSAMPRPTVEWFKSSSQI-YDGGR-FTITEEENSGVY-VLVIEDTNIEDAGTYKVVAY 1547 Query: 248 SDV-QISTEIDRSLGPV-SPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304 +++ +++++ + V + P+ K + EG D + V++ G P+P + WFK + Sbjct: 1548 NNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEKTEGDDLELTVRVRGKPQPELEWFKYDR 1607 Query: 305 RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364 L S++ + N T+ V + DSG Y +A N G + L V+ + V Sbjct: 1608 TLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQ---KKKVI 1664 Query: 365 DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424 IT +E +E G +C V+G+P P + Sbjct: 1665 GNAPDIITHLISKEVKE------------------------GGTVTLECTVSGKPAPNIE 1700 Query: 425 WFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483 W+ + +R +++ G+ A + T+ D G CVA N G RL V Sbjct: 1701 WYKDG--LRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVT 1758 Query: 484 EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI---H 540 + P+F ++ L V EG + R P P + W + I + +I + Sbjct: 1759 VPSK---PEFKQKLRPLEVVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQITEPY 1815 Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 +L I DAA Y+C A N AG T RA L Sbjct: 1816 EGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADL 1853 Score = 100 bits (239), Expect = 3e-20 Identities = 120/522 (22%), Positives = 201/522 (38%), Gaps = 49/522 (9%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 RP P I + + + + NA + G PTP W R + E + ++ Sbjct: 3 RPKGDRPQILQPL-EGVDVKEDENAILSCTISGTPTPNAEWYRDSIRVRESRR--IKSEV 59 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184 G +L IKQ D+GEY C RN++G A + + Sbjct: 60 VNGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVPVKPSFTSKMKPVDAEEGQ 119 Query: 185 TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV----DTFEYRLLREVSFRESI 240 V + + S + V Y T + + F++ + ++ EV ++ Sbjct: 120 EVRFDVH------VKGSPKPDVVWYKGSTMIGTHERFQIVEAAEDHVTLVISEVKLEDAE 173 Query: 241 TKRYVGESDV-QISTEIDRSLGP--VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297 T + V +DV ++++ D + +P I ++ G + +SG P+P + Sbjct: 174 TYKVVATNDVGKVTSRADLRVKERQFAPEFIDEERGPIDATTGDEVTLTCSVSGKPKPSI 233 Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 TW+KNG+ L +S K +I ++ + + + + D+ Y AEN G + + V++ Sbjct: 234 TWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFDVKVKA 293 Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417 P D S I T R IE E L VC+ VTG Sbjct: 294 PK----GDAPSFTIDLTHVR----AIEGEESKL------VCK---------------VTG 324 Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477 +P P + W + + + E L+I + L D+G VARN SG Sbjct: 325 KPAPTIEWLKGELPVTTSLRVRTDF-EKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSI 383 Query: 478 CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537 L V +E+ P+ + ++ GE V R G P P++ W+K I Sbjct: 384 AELQV--QERSTKPEIEDSLRDVSALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERF 441 Query: 538 RIHTDGG-ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 I + +L I + +DA Y+C A N AG + A+L Sbjct: 442 TIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQL 483 Score = 98.7 bits (235), Expect = 1e-19 Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 7/199 (3%) Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 + I K AP F+ D++V EG+ R +CRV P P V W + R ++DY+ I Sbjct: 3422 VVIESKKPAPLFIAPLHDQEVVEGETIRLECRVRATPRPMVEWKKDGRTFKEDYH--IYT 3479 Query: 443 NESGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501 G H L+I + D G C+A+NK G +L V KE ++ P F L+ Sbjct: 3480 EFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV--KEALIIPHFDHPIQDLD 3537 Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST--LDIPRAKASDAA 559 V EG+ + G P ++ W K + + + D L I K +D+ Sbjct: 3538 VIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSG 3597 Query: 560 WYQCTAQNVAGSTATRARL 578 Y C A+N AG RL Sbjct: 3598 KYTCIARNKAGENTCHGRL 3616 Score = 96.3 bits (229), Expect = 5e-19 Identities = 67/278 (24%), Positives = 114/278 (41%), Gaps = 6/278 (2%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-S 130 P E ++ G KF+ ++ G P P V W + K+ + + ++++ E++ +V S Sbjct: 395 PEIEDSLRDVSALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERFTIA--EESDEVFS 452 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVS-ETVE-- 187 L+I+ + D G Y C A N+ GEA + + V E+VE Sbjct: 453 LIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEELIGPRFEKMKESFTVVEGESVELV 512 Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247 + G E ++ + V TN D DD V T E + + G Sbjct: 513 ARVTGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGT 572 Query: 248 SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307 +D+ ++ + P+I + R + EG DA +SG P P + W KNG R+ Sbjct: 573 ADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAVLSCTISGKPVPTIEWLKNGIRVK 632 Query: 308 NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345 +S + + L ++ T+ D G YT + N G Sbjct: 633 DSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELG 670 Score = 93.9 bits (223), Expect = 3e-18 Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 8/193 (4%) Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444 +S+ + P+F + ++ V EG +F RV G P P+V WF ++I+ E Sbjct: 3229 LSKPLVMPEFKERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKKIKSHARFSSKAGE 3288 Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF----VERFSTL 500 + L I++V + D G CVA N +G+ RL+V KE++V P+ +E + L Sbjct: 3289 KHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV--KERMVPPEISTDVLEGPALL 3346 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 N EG+ + L G P P + W KDGV I + + + + G +L I D Sbjct: 3347 N--EGDDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGV 3404 Query: 561 YQCTAQNVAGSTA 573 +C A N AGS + Sbjct: 3405 IKCVAMNPAGSAS 3417 Score = 93.9 bits (223), Expect = 3e-18 Identities = 59/230 (25%), Positives = 105/230 (45%), Gaps = 12/230 (5%) Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--- 320 SPP+ ++ + G + V + G+P P + W+K+ + ++ + Sbjct: 4203 SPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFT 4262 Query: 321 -TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESPTESYVQDQRSQYITDTQQRE 378 +L +R+ + +D G Y +A+N +G +S + V E E +Q+ T Sbjct: 4263 IVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEA 4322 Query: 379 TE-ERIEISE-----KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432 E I +++ + P+F++ +D+ + E + RF CRV GRP P W D+ I Sbjct: 4323 LRMEDIPVAQSTPLKRGEPPEFIRKLRDQFIQEKETARFVCRVIGRPDPTYEWLRGDKPI 4382 Query: 433 RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 D + I+ ++ G L IT+ T+ D G+ CV+ N SG RL V Sbjct: 4383 TDGGRYTIMSDDEG-QTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTV 4431 Score = 90.6 bits (215), Expect = 3e-17 Identities = 58/203 (28%), Positives = 92/203 (45%), Gaps = 11/203 (5%) Query: 3039 QPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR 3098 QP G P + K V++ EG+ A E + +G + +EW+ +G ++ S R+R Sbjct: 2248 QPKRPEGTEPNIVSGLKS-VEVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVR 2304 Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158 + G+ L I T D GTY C+ N G+ S L + +P F + + Sbjct: 2305 STLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNII---VATRPEFKEKLTKV 2361 Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQN 3216 E + +G A FE V P+ +EWYH + R I++V + G+ L + Sbjct: 2362 E-VTEGDRAKFEVRVKGYPYPE--VEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQ 2418 Query: 3217 HDSGEYVCRAYNKYGEDFTRATI 3239 D+G Y C A NK G+ RA + Sbjct: 2419 EDAGMYKCIAVNKAGKSTCRADL 2441 Score = 90.2 bits (214), Expect = 4e-17 Identities = 129/559 (23%), Positives = 214/559 (38%), Gaps = 57/559 (10%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F V LK+ +EG E RI VG P ++ W ++ + + S ++ + +L Sbjct: 3979 PRFSVKLKNQEVIEGSTARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFAL 4036 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ-QLEDYSK 755 + ++ +D G Y A + G T + + +HP+T + D Sbjct: 4037 IVKDVSEEDDGHYKAVARNIAG----------RDVCTADISVKHPDTDEESDIDAVDARP 4086 Query: 756 YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815 + + S + +P+ + L+D + EG + F + T S P V W+KDG+P+ + Sbjct: 4087 LESKPSKPKTEIPKPEIVLGLRD-RFVVEGMSVRFNCRTT--SQPKPYVTWFKDGQPLAS 4143 Query: 816 SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875 R G SL I + DAG Y N G+A ++A + V + + Sbjct: 4144 YGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPSV-VA 4202 Query: 876 EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935 R+ E+ + T E+ KD + EGG FE E Sbjct: 4203 SPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEW---YKDDREVLEGGRIRFEQDQE- 4258 Query: 936 IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995 G T+ ++D V LT D G Y C A N G + Sbjct: 4259 -GRFTIVSLTIRD------------------VRLT-------DEGRYKCVAKNKSGTDFS 4292 Query: 996 SANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSK---RTEEEVKITQKPRFLGPLKGT 1052 SA + + D + + L K ++A R +K + P F+ L+ Sbjct: 4293 SATVKVKELDDEDSIQEGAMSLPK-STSDEALRMEDIPVAQSTPLKRGEPPEFIRKLR-D 4350 Query: 1053 NKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAED 1112 I E ++A F RV + D T EW K IT R D L+I ED Sbjct: 4351 QFIQEKETARFVCRVIGRPD--PTYEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVED 4408 Query: 1113 SGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEI 1172 G+Y V+ N++G +A +TVE + +I + L K ++E + + + I Sbjct: 4409 EGLYKCVSTNSSGTDTTTARLTVEASRRPISKNIEK-LLIKAASMDEESMSQAL--AKAI 4465 Query: 1173 SKSKPVFVQPLSNPPPVSE 1191 ++S + +P P E Sbjct: 4466 AESPELLGEPEPESKPADE 4484 Score = 89.8 bits (213), Expect = 5e-17 Identities = 61/208 (29%), Positives = 96/208 (46%), Gaps = 5/208 (2%) Query: 373 DTQQRETEERIEISEKALAPQFVKVCQDRD--VTEGKMTRFDCRVTGRPYPEVTWFINDR 430 D + + R+++ E+ + P+ + + EG R VTG P P++ W+ + Sbjct: 3314 DAGKVQCSGRLDVKERMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDLQWYKDGV 3373 Query: 431 QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490 IR H L + ++L I V D+GV+ CVA N +G + + VIE ++ A Sbjct: 3374 LIRRS-THISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTV-VIESKKP-A 3430 Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550 P F+ V EGE + L R TP P + W+KDG + + DG TL I Sbjct: 3431 PLFIAPLHDQEVVEGETIRLECRVRATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCTLVI 3490 Query: 551 PRAKASDAAWYQCTAQNVAGSTATRARL 578 A+ D Y+C A+N G + A+L Sbjct: 3491 KGAQIEDEGAYECIAKNKEGRGRSVAQL 3518 Score = 89.8 bits (213), Expect = 5e-17 Identities = 76/340 (22%), Positives = 137/340 (40%), Gaps = 33/340 (9%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+ ++ +++ +QE A +V+ +G+ + WFKN Q + + ++ + H TL++ Sbjct: 4763 PEFMEQCKSTTVQENGTAIMEVRATGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKI 4822 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 +K D G Y + N G L VE P S +D + + + + R T+ + Sbjct: 4823 SPVEKKDEGLYMCVISNKAGTADCEALLTVE-PMVSDGED-GATHGSPPKTRGTKPKKSS 4880 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 K P V + +V G + ++ WF ++ IRD + +E Sbjct: 4881 GAK---PSIVTPLANMEVFSGDDVMLEVISGPEQVKKIEWFKDNELIRDRPRFTV-TSED 4936 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ------------------ 487 H L I T D G+ CV N G + + V E E+ Sbjct: 4937 TRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIE 4996 Query: 488 -------VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI- 539 + A +F + V +G+ + + R G P P++ W KD ++ + + Sbjct: 4997 RRRSRDSICALEFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIFV 5056 Query: 540 -HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + G +L I +A D Y+C A N AG+ + +A L Sbjct: 5057 SEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAEL 5096 Score = 89.0 bits (211), Expect = 8e-17 Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 6/194 (3%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P+F +V++ +G +Y+ SL G IEW++N + I A+ R++ + Sbjct: 2157 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEGLKDGQS 3166 + + DSG Y C+A N G + K +G +P + ++++E +K+G+ Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVE-VKEGEQ 2273 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226 A E V P + EWY +G ++ S R+++ + G L I T D G Y C+ Sbjct: 2274 AELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQV 2331 Query: 3227 YNKYGEDFTRATIN 3240 N G T A +N Sbjct: 2332 RNDLGRTSTSAHLN 2345 Score = 88.2 bits (209), Expect = 1e-16 Identities = 67/250 (26%), Positives = 111/250 (44%), Gaps = 14/250 (5%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P F + K+ + EG+ A + TG + IEW +GKT+ ++ + T V Sbjct: 492 PRFEKM-KESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAV 548 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEGLKDGQS 3166 L I + DSG Y C A NK G A+++ +L+ K KG P + ++ +E +G Sbjct: 549 LTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEA-TEGDD 607 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226 A CT+ P IEW NG ++ S R K G V L I T+ D G+Y C Sbjct: 608 AVLSCTI--SGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIV 665 Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286 N+ G ++ + + +P+ K++ +++++G + Q P I Sbjct: 666 RNELGSAESKTKLK-------VIAFARPEFRTKLKPVKAVEGEEVQLDVKVEGYPKPDIE 718 Query: 3287 QIQDVTKLVE 3296 + T +VE Sbjct: 719 WYRGTTMIVE 728 Score = 82.6 bits (195), Expect = 7e-15 Identities = 73/269 (27%), Positives = 112/269 (41%), Gaps = 29/269 (10%) Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTD--MVDEVTTQA-PICTTSLKNVEIKEGQR 1594 ST I +T ++ GL + + D + +V+EV P+ LK+V + G+ Sbjct: 940 STLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNEVEKGVGPVIEEKLKDVTVMPGEE 999 Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCR 1653 A F R+ +V+W+ + L RF E + G +L I PED GTY C Sbjct: 1000 AEFSIRV----SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCL 1055 Query: 1654 AINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVF 1713 N G+ T + K++I + + A +T + AP Sbjct: 1056 VFNESGKVTTRAKLCI--KEAIVAPEEVDAA--------ETVPIEG---------SAPKI 1096 Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMK 1773 T P++ + V N+ F+ + G P VEW ++ V + S RL D L K Sbjct: 1097 TKPLESVEV--NEGEDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFK 1154 Query: 1774 YVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 PED G Y C INE G+A T+ + V Sbjct: 1155 QARPEDIGEYKCTVINEHGKASTTGEVKV 1183 Score = 82.6 bits (195), Expect = 7e-15 Identities = 81/284 (28%), Positives = 123/284 (43%), Gaps = 49/284 (17%) Query: 2062 VTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKP-----IEEEQP-GQRPVFLTAL 2115 V S + A LY TLD+ L + + + ++ ++P G P ++ L Sbjct: 2204 VQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGL 2263 Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175 S+E +KEG++A E V P T++W+ +G +++ R R+T + G L I T+ Sbjct: 2264 KSVE-VKEGEQAELEFVVSGTPTP--TLEWYRDGLRVKESRRVRSTLENGIARLVITETW 2320 Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE 2235 AED GTY C+ N LG + H NII+ T+ P EK+ T++EV Sbjct: 2321 AEDMGTYKCQVRNDLGRT------STSAHLNIIVATR-PEFKEKL---------TKVEVT 2364 Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295 E G A FE +V+ P +E+YH + RF I Sbjct: 2365 E--------------------GDRAKFEVRVKGYPYPE--VEWYHGSNRILDEDRFEIES 2402 Query: 2296 --DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 + GY SL + V EDAG Y A+N G T + V + Sbjct: 2403 VKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446 Score = 81.8 bits (193), Expect = 1e-14 Identities = 113/498 (22%), Positives = 193/498 (38%), Gaps = 85/498 (17%) Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735 E T H R + ++++ P + + +V EG P+ +++ G P ++WF Sbjct: 3609 ENTCHGR--LAVKEKMVTPSFAEGDADEPCEVWEGAPIKLIVQIK--GKPAPTVEWFKEK 3664 Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795 R V + L I D+G Y C+ATN G+ T T K+ + ++ ++ Sbjct: 3665 RQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVNEQKVVMR 3724 Query: 3796 ESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEP 3855 +P G + P F+ +++ + E R RV+ Sbjct: 3725 RQPIPPG------------------------AVKPSFLQRMQDLEIVEGSAARLCVRVQG 3760 Query: 3856 KEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGEDF 3914 +P+ I+WY++ +++ G R ++ G L I D G Y C N G Sbjct: 3761 VPEPE--IDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAG--- 3815 Query: 3915 TKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQ--- 3971 KA S + I + G+ S+A A + S + L DD D +K + Sbjct: 3816 -KAQCSAELF---IETHGFDSGV--SDADLDFAARKEARESTIELISDDTSDEEKTEGAP 3869 Query: 3972 -----PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK-NRFTPI 4025 PP F ++++ + E TKF ++ + +KVEW+ + + + R T Sbjct: 3870 KEEGAPPEFTLVLRNR-EVKEGGVTKFASRV--ISKAPIKVEWYKDDRLISSDWPRHTFE 3926 Query: 4026 YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIE 4085 +D AMN V D G Y +N YG E+KA Y + LP+ E Sbjct: 3927 HDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESKA-----------YLNVLPEMEPEFE 3975 Query: 4086 KIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWL 4145 I S ++ ++V+E S AR CR+ G P P V W Sbjct: 3976 GI-SPRFSVKLKNQEVIEGSTARLE---------------------CRIVGSPVPEVRWY 4013 Query: 4146 LNGNTIVNGSRYKLTYDG 4163 + ++ +Y++ DG Sbjct: 4014 RDNEPLIESEKYQMEQDG 4031 Score = 79.4 bits (187), Expect = 7e-14 Identities = 67/294 (22%), Positives = 114/294 (38%), Gaps = 13/294 (4%) Query: 71 PPIFEQIFKNA-RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 PP FE + +G + ++GNP P + W + + +E K + ++ Sbjct: 3039 PPGFEGPDHGSYELQEGDTITLDAVVKGNPYPEIRWYKDEFLAMESKKLMLSVRDRKN-- 3096 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET---- 185 SL + + P D G Y C +N+ G A S + E R V Sbjct: 3097 SLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKSKGIIPEFFRQLRRVEAVQGST 3156 Query: 186 --VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243 E K G + +++A + TF + + Sbjct: 3157 ARFECKVSGHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDEGDYTCVASN 3216 Query: 244 YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303 GE+ S + + P+ P+ ++ +N K+ EG +AQF V++ G P P+V WFK G Sbjct: 3217 EAGEASSHASLVLSK---PLVMPEFKERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTG 3273 Query: 304 QRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356 +++ + + HT TL + + D G Y +A N G + SG L V+ Sbjct: 3274 KKIKSHARFSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVK 3327 Score = 79.0 bits (186), Expect = 9e-14 Identities = 55/213 (25%), Positives = 96/213 (45%), Gaps = 25/213 (11%) Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 + P+I R+ + EG +F + + P+P VTWFK+GQ L + ++E+ + + Sbjct: 4098 IPKPEIVLGLRDRFVVEGMSVRFNCRTTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQS 4157 Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382 L +++ + +D+G Y N G TS +L VE +S Sbjct: 4158 LTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKS--------------------- 4196 Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 S A P+F + + G T+ + G P P + W+ +DR++ + + Sbjct: 4197 -RPSVVASPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQ 4255 Query: 443 NESGNH---ALMITNVTLSDSGVVTCVARNKSG 472 ++ G +L I +V L+D G CVA+NKSG Sbjct: 4256 DQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSG 4288 Score = 78.2 bits (184), Expect = 2e-13 Identities = 89/387 (22%), Positives = 155/387 (40%), Gaps = 32/387 (8%) Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 + P F + M + V E A FE R+ G PKL+VEW + IE S R T D Sbjct: 1185 VLSRPEFKIKMSPVEVTEGSEAAFEVRV--EGFPKLQVEWFKGMTKIEDSGRYTFTADKN 1242 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA-SLQLESQH---ESALQKIQ 1822 + + V ED+G Y C A N G+ + + L V+ + + + E++ +S + K Sbjct: 1243 RYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTIDSEVNKEV 1302 Query: 1823 QLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF 1882 +++ ++ R+ + V T KLS+ + Y+C+ R W Sbjct: 1303 EIKVTTGEPIRDSINTDVRAIGDSHTCFIVRAKLSD--AGVYKCQATNAAGSASR-SW-- 1357 Query: 1883 NGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAI-----NNLGQAVSSIRLNVQ 1937 KV QS + L + + CK ++ +++ Sbjct: 1358 EVKVKQSAPKTTGEEPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKIREN 1417 Query: 1938 SKESIIRDSQHESALEKIQYLEDDSRYKRAVQDD------------SFVVEKPQFGKPIK 1985 S+ ++ D + S + L+D+ YK + ++ + V +P F + +K Sbjct: 1418 SRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKLK 1477 Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYVALDILYAY 2043 EG E L+ + PT VEW+ + + G RF T + G L I Sbjct: 1478 AVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTN 1535 Query: 2044 AEDTGTYMCKATNAVGEAVTTSSVKVD 2070 ED GTY A N +G+ + + ++V+ Sbjct: 1536 IEDAGTYKVVAYNNLGKVTSQALLRVN 1562 Score = 74.9 bits (176), Expect = 1e-12 Identities = 65/248 (26%), Positives = 101/248 (40%), Gaps = 15/248 (6%) Query: 625 IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684 +P V PP+F LK V + G I +G PT IEW K+ + + R Sbjct: 4193 LPKSRPSVVASPPRFQEELKGVITVVGTTTKLSVPI--IGHPTPVIEWYKDDREVLEGGR 4250 Query: 685 FT----SIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQH 740 RF +SL + + + D G Y C A + +G + A + V + + S Sbjct: 4251 IRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKV--KELDDEDSIQ 4308 Query: 741 PETLQYIQQLEDYSKYQHQESIEEQT----SQRPQFIRPLQDLGELQEGRNAHFEAQLTP 796 + + D + + + T + P+FIR L+D +QE A F ++ Sbjct: 4309 EGAMSLPKSTSDEALRMEDIPVAQSTPLKRGEPPEFIRKLRD-QFIQEKETARFVCRVIG 4367 Query: 797 VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856 DPT EW + +PIT R T + + +L I ED G Y + N G + Sbjct: 4368 RPDPT--YEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTT 4425 Query: 857 TASIRVAA 864 TA + V A Sbjct: 4426 TARLTVEA 4433 Score = 74.1 bits (174), Expect = 2e-12 Identities = 79/336 (23%), Positives = 136/336 (40%), Gaps = 30/336 (8%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129 P F Q+ + QG A+FE K+ G+P P ++W + L +Y + + G+V Sbjct: 3140 PEFFRQL-RRVEAVQGSTARFECKVSGHPEPQIAWLKDGKELA-IPRYIKPFYD--GEVC 3195 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEA-------ICSVYIQPEGXXXXXXXXXXXXXYRHV 182 L + P DEG+YTC A N+ GEA + + PE Sbjct: 3196 KLTFYETQPEDEGDYTCVASNEAGEASSHASLVLSKPLVMPEFKERLKNIKVVEGDEAQF 3255 Query: 183 SETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL-LREVSFRESIT 241 S V+ G E + +K+ H+ + Y L + +V+ + T Sbjct: 3256 SVRVK----GEPEPKVEWFKTGKKIK-----SHARFSSKAGEKHTYTLTISDVAMEDFGT 3306 Query: 242 KRYVGESD---VQISTEIDRSLGPVSPPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPR 296 + V +D VQ S +D V PP+I+ L EG D + V ++GNP P Sbjct: 3307 YKCVASNDAGKVQCSGRLDVKERMV-PPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPD 3365 Query: 297 VTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356 + W+K+G + S + + + +L + D+G +A NP G S + +E Sbjct: 3366 LQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIE 3425 Query: 357 S--PTESYVQDQRSQYITDTQQRETEERIEISEKAL 390 S P ++ Q + + + E R+ + + + Sbjct: 3426 SKKPAPLFIAPLHDQEVVEGETIRLECRVRATPRPM 3461 Score = 72.5 bits (170), Expect = 8e-12 Identities = 79/339 (23%), Positives = 135/339 (39%), Gaps = 40/339 (11%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 VEW K+ R + + F L I D+G+Y C+A N G T + + + Sbjct: 3658 VEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVN 3717 Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062 +K ++ P G K P FL ++ +IVEG +A Sbjct: 3718 EQKVVMRRQPIPPGAVK-----------------------PSFLQRMQDL-EIVEGSAAR 3753 Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANRIQ-TYHDFGYVALDIASVRAEDSGVYTVVAR 1121 RV+ + ++WY + + I R++ + + G L I D G Y V Sbjct: 3754 LCVRVQGVPE--PEIDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVS 3811 Query: 1122 NAAGEAQLSASMTVETR---SSIDTSSIHRGLYEKTRH------IEESKFVEPMYQIEEI 1172 NAAG+AQ SA + +ET S + + + ++ R +++ E + Sbjct: 3812 NAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELISDDTSDEEKTEGAPKE 3871 Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY-YD 1231 + P F L N V EG R+ + ++VEW+ + R ++ T+ +D Sbjct: 3872 EGAPPEFTLVLRN-REVKEGGVTKFASRV--ISKAPIKVEWYKDDRLISSDWPRHTFEHD 3928 Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270 A++I + AD G YT N G+ + A + V+ Sbjct: 3929 EDLYAMNISNVKVADGGPYTFVVSNKYGTVESKAYLNVL 3967 Score = 72.1 bits (169), Expect = 1e-11 Identities = 146/579 (25%), Positives = 220/579 (37%), Gaps = 93/579 (16%) Query: 1809 QLESQHESALQKIQQLEDSSRYQ---------RREDVEVAVNQAPRFITQLNGPTK---L 1856 + + QH + + K Q+ED Y+ R ++ V +A I + P + + Sbjct: 3480 EFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKEA-LIIPHFDHPIQDLDV 3538 Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND--FGFAALDILTVYGEDS 1914 EG A + +E P +VEW + L++G R D L I DS Sbjct: 3539 IEGDRAKFH--VEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDS 3596 Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974 G+YTC A N G+ RL V KE ++ S + E D+ D+ Sbjct: 3597 GKYTCIARNKAGENTCHGRLAV--KEKMVTPS----------FAEGDA-------DEPCE 3637 Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034 V + G PIK +G P PT VEW+ R ++ K + Sbjct: 3638 VWE---GAPIKLIVQIKGKPA-----------PT--VEWFKEKRQAKRLKNVKLFTEGDK 3681 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094 L I A ED+G Y C+ATN G T V V +EQ++ Sbjct: 3682 HMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVV-----------NEQKV--------V 3722 Query: 2095 ERPKPIEEEQPGQ-RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR 2153 R +PI PG +P FL + LE + EG A RV+ + +P IDW+ + + IR Sbjct: 3723 MRRQPI---PPGAVKPSFLQRMQDLE-IVEGSAARLCVRVQGVPEPE--IDWYKDNRVIR 3776 Query: 2154 AGHRYR-TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGH------RN 2206 G R + G L I D G Y C +N G+A + L + H + Sbjct: 3777 EGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSD 3836 Query: 2207 IILD-TQHPNGLEKIRQLEAQGHSTRIEVE-EPKI--SPPRFVTELRGTTHVFEGKTAHF 2262 LD E +L + S + E PK +PP F LR V EG F Sbjct: 3837 ADLDFAARKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLR-NREVKEGGVTKF 3895 Query: 2263 ECQVEPVHDPNLRIEFYHNGKALQSA-ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAIN 2321 +V + +++E+Y + + + S R D +++I + D G Y+ N Sbjct: 3896 ASRV--ISKAPIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSN 3953 Query: 2322 ALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360 G S + V + E P K++ E E Sbjct: 3954 KYGTVESKAYLNVLPEMEPEFEGISPRFSVKLKNQEVIE 3992 Score = 70.9 bits (166), Expect = 2e-11 Identities = 62/232 (26%), Positives = 99/232 (42%), Gaps = 29/232 (12%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDFGYVA 1769 PV +KD+ V + A F R+ + V+W ++ V + R + D G + Sbjct: 983 PVIEEKLKDVTVMPGEEAEFSIRV----SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFS 1038 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829 L + V PED GTY C NE G+ T + L + K ++ + ++A Sbjct: 1039 LTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI--KEAIVAPEEVDAA------------ 1084 Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889 E V + AP+ L +++EG+ EC + P P VEW + L++ Sbjct: 1085 ----ETVPIE-GSAPKITKPLES-VEVNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRT 1136 Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQSK 1939 +R + D A L ED GEY C IN G+A +++NV S+ Sbjct: 1137 SYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSR 1188 Score = 70.9 bits (166), Expect = 2e-11 Identities = 89/348 (25%), Positives = 138/348 (39%), Gaps = 48/348 (13%) Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118 ++ EG+ E + T ++EW +G+T + + I T + L I G + D Sbjct: 3441 EVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYTEFDGQHCTLVIKGAQIEDE 3498 Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178 G Y C A NK G+ +L K P F IQ+++ + +G A F V Sbjct: 3499 GAYECIAKNKEGRGRSVAQLTV--KEALIIPHFDHPIQDLDVI-EGDRAKFHVEV--SGK 3553 Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236 P K+EW Q +R+ R+ D L I + DSG+Y C A NK GE+ Sbjct: 3554 PAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSGKYTCIARNKAGEN--- 3610 Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296 C+G+ V + + P S A +G + P K I QI+ Sbjct: 3611 ---TCHGRLAVKEKMVTP-SFA--------EGDADEPCEVWEGAPIKLIVQIK------- 3651 Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356 P VEWF ++ + F + +L I E+SG Y Sbjct: 3652 -------------GKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYR 3698 Query: 3357 CVATNKLGRDSTKANLKCTSKENLILDSQ-LPRG--MEGGLEKLQTLE 3401 C ATN G TK +++ +++ Q +P G L+++Q LE Sbjct: 3699 CQATNDAG-TVTKTFKVVVNEQKVVMRRQPIPPGAVKPSFLQRMQDLE 3745 Score = 70.1 bits (164), Expect = 4e-11 Identities = 118/531 (22%), Positives = 206/531 (38%), Gaps = 64/531 (12%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFT---ETNNF 1632 P T LK V+ EG+ + ++ P D +EWY + RF E Sbjct: 686 PEFRTKLKPVKAVEGEEVQLDVKVEGYPKPD----IEWYRGTTMIVESGRFKVMEEEEED 741 Query: 1633 GFVALDIMSCLPEDSGTYTCRAINALGEAVT-SGIAIVHSKKSIYLESQHEGALPRLN-- 1689 G +L I +D+GT A NA G+A + + + + + + E EG + Sbjct: 742 GLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKEREFAPEFEGDEEGPIVVTEGN 801 Query: 1690 --QLEDTSKYQRHSAQDEVITQAPVFTMPMKDI--RVAENQAAHFEARLIPVGDPKLRVE 1745 ++ K ++ D P++ +DI R E+ A + L G K Sbjct: 802 EVSIQLRVKANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEAS 861 Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDS--GTYTCRAINELGEAV-----TSS 1798 ++ G + + + P ++ G T G+ T Sbjct: 862 NRLGKASRSFDVKVQVKGPKGEAPIILSKLRPVETEEGEETKLKCTFTGKPAPTCEWTRD 921 Query: 1799 TLFVQSKASLQLESQHESALQKIQQ--LEDSSRYQR--REDVEVAVNQAPRFITQLN--- 1851 + ++S +Q+++ +S+ I++ L+D Y+ + D+ A + ++ Sbjct: 922 GIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNEVEKGV 981 Query: 1852 GPT---KLSE-----GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY-RTSNDFGFA 1902 GP KL + G+ A + R+ + V+W+ + +L R+ D G Sbjct: 982 GPVIEEKLKDVTVMPGEEAEFSIRVSGRAE----VDWFKDEVMLNDEGRFIMEGGDNGRF 1037 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962 +L I V ED G Y C N G+ + +L + KE+I+ + ++A E + +E + Sbjct: 1038 SLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI--KEAIVAPEEVDAA-ETVP-IEGSA 1093 Query: 1963 RYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ 2022 P+ KP+++ EV EG LE ++ PT VEW + ++ Sbjct: 1094 ---------------PKITKPLESVEVNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRT 1136 Query: 2023 GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 +R K D L A ED G Y C N G+A TT VKV+ S Sbjct: 1137 SYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLS 1187 Score = 70.1 bits (164), Expect = 4e-11 Identities = 54/227 (23%), Positives = 105/227 (46%), Gaps = 38/227 (16%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 + VEE +++ P+F+ ++ G + +G +++ +E P IE+YHN + + + +R Sbjct: 2148 LHVEE-ELTIPQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRV 2204 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 ++F ++ + + +D+G Y KA+N G + ++ V K RPEG E Sbjct: 2205 QLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK--------RPEGTE 2256 Query: 2352 KIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVE 2411 P L++++ ++EG+ A + + G PT +E Sbjct: 2257 ------------------------PNIVSGLKSVE-VKEGEQAELE--FVVSGTPTPTLE 2289 Query: 2412 WFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 W+R+ +++S R+ T + G + I+ ED G Y C+ N LG Sbjct: 2290 WYRDGLRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQVRNDLG 2336 Score = 69.7 bits (163), Expect = 5e-11 Identities = 67/297 (22%), Positives = 128/297 (43%), Gaps = 32/297 (10%) Query: 2944 KIEWYFNGKVLEQGSRFKLTS-DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002 +++W+ + +L RF + D G +L + DV D G Y C +N+ G+ T + + Sbjct: 1011 EVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKL- 1069 Query: 3003 CTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISE 3062 C K+ ++ P+ + E + +E G P+ T + V+++E Sbjct: 1070 CI-KEAIVA----PEEVDAAETVP-IE---------------GSAPKITKPLES-VEVNE 1107 Query: 3063 GQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYS 3122 G+ ++ + +G S +EW + + S+R++ + L + D G Y Sbjct: 1108 GE--DFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYK 1165 Query: 3123 CRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMK 3182 C N+ G+A + +++ S+ P F + +E + +G A FE V P ++ Sbjct: 1166 CTVINEHGKASTTGEVKVNVLSR---PEFKIKMSPVE-VTEGSEAAFEVRVEGF--PKLQ 1219 Query: 3183 IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239 +EW+ + S R +D + IA D+G Y C A N G+ +RA + Sbjct: 1220 VEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADL 1276 Score = 69.7 bits (163), Expect = 5e-11 Identities = 96/393 (24%), Positives = 150/393 (38%), Gaps = 75/393 (19%) Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQ-APRFIT-QLNGPTKLSEGQSAHYECRIEP 1870 Q ++ + K + + + R D+EV Q AP F T + GP + EG + + Sbjct: 2418 QEDAGMYKCIAVNKAGKSTCRADLEVNERQFAPEFETGEERGPIVVPEGGETTLKVTLRA 2477 Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930 P P +V WY +GK R + L I EDSG Y C+A N LG A Sbjct: 2478 NPKP--QVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADK 2535 Query: 1931 SIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVT 1990 S + V+ + + + L+++Q ++ ++ ++ +E GKP Sbjct: 2536 SFTIRVEVPKP---TGEEPTILQRLQPVD-------TIEGEAIKMECRVSGKP------- 2578 Query: 1991 EGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTY 2050 +PT + W +G +R KT +D L I D G Y Sbjct: 2579 ---------------EPT--ITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIY 2621 Query: 2051 MCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPV 2110 C A N+ G A +++ + V LE+ RP+ +E+ Q V Sbjct: 2622 RCNAKNSSGSAHSSAELTV---------------------LEREARPRILEKLQDVDSSV 2660 Query: 2111 FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDFGYVAL 2169 G+RA F+ RV P + W+ ++I GH GY +L Sbjct: 2661 -------------GERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSL 2705 Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202 I Y ED G Y N GE +T L++A Sbjct: 2706 TIEYIDYEDEGAYKAVVINDSGEVSSTAVLRLA 2738 Score = 69.7 bits (163), Expect = 5e-11 Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 16/134 (11%) Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638 +D G+Y C A N AG C AE +V PA D+ AA ++ G Sbjct: 5938 EDEGEYTCRASNPAGSCSCTAELIVDAPAKVDQ------AATPGSGVV----------GG 5981 Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698 I +C I G P+PT W++GD+ +K + T D +L I DEG+Y+ V Sbjct: 5982 KITLTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVK 6041 Query: 4699 NSAGRVTVAAKLKV 4712 N G + KL V Sbjct: 6042 NDGGEDSCVVKLTV 6055 Score = 69.3 bits (162), Expect = 7e-11 Identities = 80/345 (23%), Positives = 132/345 (38%), Gaps = 48/345 (13%) Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312 ST + + +S P+ K ++ EG++A F+V++ G P+ +V WFK ++ +S ++ Sbjct: 1176 STTGEVKVNVLSRPEFKIKMSPVEVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRY 1235 Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYIT 372 T +D YT++ N GY V + T + Sbjct: 1236 ---------------TFTADKNRYTMVIANVT-LEDAGGYRCVATNTAGKTTSRAD---- 1275 Query: 373 DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432 + + E+ AP+F + RD T D V +VT I Sbjct: 1276 ----------LTVKEREFAPEF----ETRDDT------IDSEVNKEVEIKVT---TGEPI 1312 Query: 433 RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE---KEQVV 489 RD N + +H I LSD+GV C A N +G + + V + K Sbjct: 1313 RDSINTDVRAI-GDSHTCFIVRAKLSDAGVYKCQATNAAGSASRSWEVKVKQSAPKTTGE 1371 Query: 490 APKFVERFSTLNVREGEPVVLNARAVGT-PTPRITWQKDGVPIIPNPELRIHTDGGASTL 548 P + + + EG L + P P I W +DGV I N +++ DG +L Sbjct: 1372 EPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKIRENSRIKMVFDGETCSL 1431 Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRL 593 I A D Y+ T N G+ ++ R+ Q++L Sbjct: 1432 TIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKL 1476 Score = 68.1 bits (159), Expect = 2e-10 Identities = 77/317 (24%), Positives = 125/317 (39%), Gaps = 29/317 (9%) Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117 V+ EG+ + + TG + EW +G I +S ++ L I T D Sbjct: 894 VETEEGEETKLKCTF--TGKPAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDD 951 Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177 G Y C N G S ++ + KG P ++++ + G+ A F V Sbjct: 952 EGLYKCTIKNDLGTVSTSAEVLVNEVEKGVGPVIEEKLKDVT-VMPGEEAEFSIRV---- 1006 Query: 3178 DPDMKIEWYHNGQPMRHSTR-IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236 +++W+ + + R I D G L I+ + D G Y C +N+ G+ TR Sbjct: 1007 SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTR 1066 Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296 A + C + V E + A + P SA PK IT+ + ++ E Sbjct: 1067 AKL-CIKEAIVAPEEVD---------------AAETVPIEGSA--PK-ITKPLESVEVNE 1107 Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356 G+ F+ V P VEW + KL +R + D + L E+ GEY+ Sbjct: 1108 GED--FDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYK 1165 Query: 3357 CVATNKLGRDSTKANLK 3373 C N+ G+ ST +K Sbjct: 1166 CTVINEHGKASTTGEVK 1182 Score = 68.1 bits (159), Expect = 2e-10 Identities = 122/519 (23%), Positives = 190/519 (36%), Gaps = 61/519 (11%) Query: 3413 EEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRF-RT 3471 E EKG PV L ++ + GE A F R++ +V+W+ + L RF Sbjct: 976 EVEKGVGPVIEEKLKDV-TVMPGEEAEFSIRVSG----RAEVDWFKDEVMLNDEGRFIME 1030 Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT 3531 D G L IS PED G Y C +N G+ T A + ++ Sbjct: 1031 GGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIK------------------ 1072 Query: 3532 IDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV 3591 + I A E VD G+ P+ T + ++E EC + S V Sbjct: 1073 -EAIVAPE----EVDAAETVPIEGSAPKITKPLESVEVNEGEDFDLEC--VVSGSPSPTV 1125 Query: 3592 EWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA--TVSCKLQV 3649 EW + L T R+K D L D G Y C N HG+A T K+ V Sbjct: 1126 EWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNV 1185 Query: 3650 KGRQ--GIILEP-----QLPSHFKSGTESIQKLE----ETLHKREEITIEDEKPNPPRFT 3698 R I + P + F+ E KL+ + + K E+ + R+T Sbjct: 1186 LSRPEFKIKMSPVEVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYTFTADKNRYT 1245 Query: 3699 VEIKDNIDVPEGGPVHFDC-RVEPVGDPTMRIDWFHNGRPFAT--GSRVHTLNDFGFIAL 3755 + I N+ + + G + C G T R D R FA +R T++ + Sbjct: 1246 MVIA-NVTLEDAG--GYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTIDSEVNKEV 1302 Query: 3756 DIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGR 3815 +I + G + T + V + Q +G + E Sbjct: 1303 EIKVTTGEPIRDSINTDVRAIGDSHTCFIVRAKLSDAGVYKCQATNA-AGSASRSWEVKV 1361 Query: 3816 ISDAPK---EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872 APK EEPI+ I ++++ ++E C+V + P+ I+W R+G + Sbjct: 1362 KQSAPKTTGEEPII------IRKLQAQEIDEGSTANLVCKVTAAK-PEPSIKWTRDGVKI 1414 Query: 3873 PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 R + V+D SL I +D G Y N++G Sbjct: 1415 RENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYG 1453 Score = 66.9 bits (156), Expect = 4e-10 Identities = 65/242 (26%), Positives = 101/242 (41%), Gaps = 44/242 (18%) Query: 3679 LHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF 3738 LH EE+TI P+F ++ +++ +G ++D +E G P I+W+HN R Sbjct: 2148 LHVEEELTI-------PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLI 2198 Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798 SRV + + + D+G Y C+ A TA T S + +I ++ + Sbjct: 2199 YATSRVQLSFISSKATIALYNVTLDDSGLYRCK-------AVNTAG-TGSKQFNINVQPK 2250 Query: 3799 LPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKED 3858 P+G T P ++ +KS V+E E E V Sbjct: 2251 RPEG-------------------------TEPNIVSGLKSVEVKEGEQAELEFVVSGTPT 2285 Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKAT 3918 P L EWYR+G + R R+ + G L I +AED G Y C+ ND G T A Sbjct: 2286 PTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAH 2343 Query: 3919 IS 3920 ++ Sbjct: 2344 LN 2345 Score = 66.9 bits (156), Expect = 4e-10 Identities = 53/194 (27%), Positives = 81/194 (41%), Gaps = 6/194 (3%) Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106 PP F ++ EG +A + G+ I W+ + S ++ Sbjct: 3039 PPGFEGPDHGSYELQEGDTITLDA--VVKGNPYPEIRWYKDEFLAMESKKLMLSVRDRKN 3096 Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165 L + DSG Y C NK G A S ++ KSKG P F ++ +E ++ G Sbjct: 3097 SLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKSKGIIPEFFRQLRRVEAVQ-GS 3155 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 +A FEC V P+ +I W +G+ + IK D L TQ D G+Y C Sbjct: 3156 TARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDEGDYTCV 3213 Query: 3226 AYNKYGEDFTRATI 3239 A N+ GE + A++ Sbjct: 3214 ASNEAGEASSHASL 3227 Score = 66.1 bits (154), Expect = 7e-10 Identities = 56/221 (25%), Positives = 94/221 (42%), Gaps = 12/221 (5%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 PEF + +D + G S+ +G I W+ NGK + S ++ + Sbjct: 201 PEFIDEERGPIDATTGDEVTLTCSV--SGKPKPSITWYKNGKLLTDSLKLDIRSSGERNW 258 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 + +L K D+ Y C A NK G+A + ++ V KG P FT + ++ + +G+ + Sbjct: 259 VTMLSAKPEDTALYKCEAENKLGKASRAFDVK-VKAPKGDAPSFTIDLTHVRAI-EGEES 316 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 C V P IEW P+ S R++T + L I T+ D+G Y A Sbjct: 317 KLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVAR 374 Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQG 3268 N G + A + V S +P+ +R++ +L G Sbjct: 375 NDSGTAHSIAELQ------VQERSTKPEIEDSLRDVSALPG 409 Score = 65.7 bits (153), Expect = 9e-10 Identities = 76/280 (27%), Positives = 116/280 (41%), Gaps = 44/280 (15%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P+F K ++ V EG V L A +T P +EW +G+ V++ + T L Sbjct: 492 PRFEKMKESFTVVEGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVL 549 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097 I + +D+G Y C A N KSG T D +Q ++P Sbjct: 550 TIEESSRDDSGLYRCTARN---------------KSG----TADMTFQLDVQP----KKP 586 Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157 K G P ++ L +E EGD A C + P TI+W NG +++ R Sbjct: 587 K-------GTAPEIVSELRPVE-ATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRR 636 Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGL 2217 + G V L I T A+D G Y C N+LG A + LKV + P Sbjct: 637 TKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV-------IAFARPEFR 689 Query: 2218 EKIRQLEA-QGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256 K++ ++A +G +++V+ P + RGTT + E Sbjct: 690 TKLKPVKAVEGEEVQLDVKVEGYPKPD-IEWYRGTTMIVE 728 Score = 64.9 bits (151), Expect = 2e-09 Identities = 48/189 (25%), Positives = 81/189 (42%), Gaps = 11/189 (5%) Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118 ++ EG E ++ +G + IEW+ +G A+ R+ T + + + + D Sbjct: 1678 EVKEGGTVTLECTV--SGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDD 1735 Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178 G Y C ATN G A+ S +L S KP F ++ +E + +G A F+ + Sbjct: 1736 GEYKCVATNPLGSAQSSARLTVTVPS---KPEFKQKLRPLE-VVEGSEAKFDVRIKSYPK 1791 Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDF---GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235 P+ +EWY + S R + + L I T D+ Y C A+N+ G+ Sbjct: 1792 PE--VEWYRGTTKITDSLRHQITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTC 1849 Query: 3236 RATINCYGK 3244 RA + K Sbjct: 1850 RADLTVIEK 1858 Score = 64.9 bits (151), Expect = 2e-09 Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 5/115 (4%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P+F R L +E V+G+ EC++ G ++ W +GK + +P Y+ + L Sbjct: 3140 PEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKL 3197 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425 PED G YTC A+N+ GEA + +L + K L++ + L+ I+ +E Sbjct: 3198 TFYETQPEDEGDYTCVASNEAGEASSHASL--VLSKPLVM-PEFKERLKNIKVVE 3249 Score = 63.7 bits (148), Expect = 3e-09 Identities = 45/150 (30%), Positives = 71/150 (47%), Gaps = 9/150 (6%) Query: 3110 ILGTKTTDSGTYSCRATNKWGQA----EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165 I+ K +D+G Y C+ATN G A E+ VK + K+ G++P +Q E + +G Sbjct: 1331 IVRAKLSDAGVYKCQATNAAGSASRSWEVKVK-QSAPKTTGEEPIIIRKLQAQE-IDEGS 1388 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 +A+ C V P+ I+W +G +R ++RIK V D L I D G Y Sbjct: 1389 TANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVT 1447 Query: 3226 AYNKYG--EDFTRATINCYGKGGVYLESLQ 3253 N+YG R +N G ++ + L+ Sbjct: 1448 LTNEYGTASSTCRVLVNEVGSRPIFQQKLK 1477 Score = 63.7 bits (148), Expect = 3e-09 Identities = 36/97 (37%), Positives = 53/97 (54%), Gaps = 3/97 (3%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 + AP THL S + + EG V LE V + PN IEW+K+G+ T R+ +TFD Sbjct: 1664 IGNAPDIITHLISKE-VKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMTTFDG 1720 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 + +++ + D G Y C ATN LG A S+A + + Sbjct: 1721 SVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757 Score = 63.7 bits (148), Expect = 3e-09 Identities = 54/186 (29%), Positives = 77/186 (41%), Gaps = 8/186 (4%) Query: 3047 PPEFTT-VFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105 PPE +T V + ++EG S+ TG+ ++W+ +G I S I Sbjct: 3332 PPEISTDVLEGPALLNEGDDLRLVVSV--TGNPIPDLQWYKDGVLIRRSTHISLSSIGSR 3389 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165 L I+G D+G C A N G A S V +SK P F + + E + +G+ Sbjct: 3390 YSLAIMGVVPEDTGVIKCVAMNPAGSA--SKSFTVVIESKKPAPLFIAPLHDQE-VVEGE 3446 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 + EC V P +EW +G+ + I T D L I Q D G Y C Sbjct: 3447 TIRLECRVRATPRP--MVEWKKDGRTFKEDYHIYTEFDGQHCTLVIKGAQIEDEGAYECI 3504 Query: 3226 AYNKYG 3231 A NK G Sbjct: 3505 AKNKEG 3510 Score = 63.3 bits (147), Expect = 5e-09 Identities = 64/232 (27%), Positives = 101/232 (43%), Gaps = 32/232 (13%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRY-RTFHDFGIV 3340 P +++DVT ++ G+ A F R+ +V+WF + L R+ D G Sbjct: 983 PVIEEKLKDVT-VMPGEEAEFSIRV----SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRF 1037 Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400 L I E+ G Y+C+ N+ G+ +T+A L C KE ++ E++ Sbjct: 1038 SLTISDVRPEDKGTYKCLVFNESGKVTTRAKL-CI-KEAIVAP-----------EEVDAA 1084 Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460 E + +G AP T PL ++E + EGE+ F+ + P+ VEW + Sbjct: 1085 ETVPI----------EGSAPKITKPLESVE-VNEGED--FDLECVVSGSPSPTVEWTKDL 1131 Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 L+ R + D L PED GEY C N +G+A TT +KV Sbjct: 1132 VKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183 Score = 63.3 bits (147), Expect = 5e-09 Identities = 36/94 (38%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 +PEFK + + + EG A FE R+E G L+VEW K +E S R T + Sbjct: 1188 RPEFKIKMSP-VEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 + I +VT+ DAG Y C A N G+ T+ A+LT+ Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278 Score = 62.5 bits (145), Expect = 8e-09 Identities = 82/324 (25%), Positives = 129/324 (39%), Gaps = 52/324 (16%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 G P FT + I EG+ + + TG + IEW + S R+RT + Sbjct: 296 GDAPSFTIDLTHVRAI-EGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDFEKN 352 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 + L I T+ D+GTY A N G A +L+ ++S KP ++++ L G Sbjct: 353 VATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERST--KPEIEDSLRDVSALP-G 409 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR--IKTVSD--FGFVVLDIAYTQNHDSG 3220 + F+ + P K+EW + R I SD F ++ D+ T D+G Sbjct: 410 ERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEET---DAG 464 Query: 3221 EYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE 3280 Y C A N E+ + +S+A++ E L G Sbjct: 465 RYKCVATN---------------------EAGEAESMAQLTVNEELIG------------ 491 Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340 P+F + T +VEG+S AR+ P+ +EW +GK + + T Sbjct: 492 -PRFEKMKESFT-VVEGESVELVARVTGKPAPE--IEWTKDGKTVRKTNNVDTKERDDQA 547 Query: 3341 ILDILYCYEENSGEYECVATNKLG 3364 +L I ++SG Y C A NK G Sbjct: 548 VLTIEESSRDDSGLYRCTARNKSG 571 Score = 62.5 bits (145), Expect = 8e-09 Identities = 73/282 (25%), Positives = 114/282 (40%), Gaps = 39/282 (13%) Query: 994 TTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGP----- 1048 TT + T++ K+ + + GL K D S T EV + + + +GP Sbjct: 935 TTEDSSTLIIKETTLDDE----GLYKCTIKNDLGTVS--TSAEVLVNEVEKGVGPVIEEK 988 Query: 1049 LKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR-IQTYHDFGYVALDIAS 1107 LK ++ G+ A F RV +++ V+W+ + + R I D G +L I+ Sbjct: 989 LKDVT-VMPGEEAEFSIRVSGRAE----VDWFKDEVMLNDEGRFIMEGGDNGRFSLTISD 1043 Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMY 1167 VR ED G Y + N +G+ A + ++ E EE E + Sbjct: 1044 VRPEDKGTYKCLVFNESGKVTTRAKLCIK---------------EAIVAPEEVDAAETV- 1087 Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227 I S P +PL + V+EG++ LEC + G P+ VEW + + R K Sbjct: 1088 ---PIEGSAPKITKPLESVE-VNEGEDFDLECVVS--GSPSPTVEWTKDLVKLRTSYRLK 1141 Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269 D L A D GEY +N G A T+ V+V Sbjct: 1142 EKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183 Score = 62.1 bits (144), Expect = 1e-08 Identities = 84/355 (23%), Positives = 136/355 (38%), Gaps = 63/355 (17%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 G+ P+ L+ L +E +EG+ +C P T +W +G +IR+ Sbjct: 882 GEAPIILSKLRPVET-EEGEETKLKCTFT--GKPAPTCEWTRDGIRIRSSRM-------- 930 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225 V +D EDS T + K T E + CT+K L Sbjct: 931 -VQIDT----TEDSSTLIIKETTLDDEGLYKCTIK--------------------NDLGT 965 Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285 S + V E + + E V G+ A F +V ++++ + L Sbjct: 966 VSTSAEVLVNEVEKGVGPVIEEKLKDVTVMPGEEAEFSIRVSG----RAEVDWFKDEVML 1021 Query: 2286 QSAARFHITF-DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344 RF + D G SL I PED G Y N G T+ + + K +I++ Sbjct: 1022 NDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI--KEAIVA-- 1077 Query: 2345 QRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVG 2404 PE E+++AE P+ P T+PL++++ + EG+ FD + G Sbjct: 1078 --PE------EVDAAETV-------PIEGSAPKITKPLESVE-VNEGED--FDLECVVSG 1119 Query: 2405 DPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 P+ VEW ++ + S R+ + D + R ED G Y C N G+ Sbjct: 1120 SPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGK 1174 Score = 62.1 bits (144), Expect = 1e-08 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 3/98 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 + P L+ D +EG+ + +E +V + +P I W K+G+ T R+K+ FD + Sbjct: 2549 EEPTILQRLQPVDT-IEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDV 2605 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 TL+I ++ D GIY C A N G A S+A + + +R Sbjct: 2606 CTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLER 2643 Score = 61.3 bits (142), Expect = 2e-08 Identities = 50/203 (24%), Positives = 82/203 (40%), Gaps = 20/203 (9%) Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGAR-LKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721 EA+ R +++WFK+ V L R + D G +L+I+ +R +D G Y C N Sbjct: 999 EAEFSIRVSGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFN 1058 Query: 2722 LLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLN 2781 G+ + A + I++ + P+ +D + L Sbjct: 1059 ESGKVTTRAKLCIKEA------IVAPEEVDAAETVPIEGSAPKIT-----------KPLE 1101 Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841 ++ EG++ EC V S PT +EW + L + R K D + L E Sbjct: 1102 SVEVNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPE 1159 Query: 2842 DSGIYTCKATNSKGSATTSGSLR 2864 D G Y C N G A+T+G ++ Sbjct: 1160 DIGEYKCTVINEHGKASTTGEVK 1182 Score = 60.9 bits (141), Expect = 2e-08 Identities = 64/243 (26%), Positives = 92/243 (37%), Gaps = 28/243 (11%) Query: 3683 EEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742 E + E EK P ++KD + V G F RV + +DWF + Sbjct: 971 EVLVNEVEKGVGPVIEEKLKD-VTVMPGEEAEFSIRVSGRAE----VDWFKDEVMLNDEG 1025 Query: 3743 R-VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801 R + D G +L I + D G Y C N+ G TT AK+ C K IV ++ Sbjct: 1026 RFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKL-C-IKEAIVAPEEV-- 1081 Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861 DA + PI + PK ++S V E E EC V P Sbjct: 1082 ----------------DAAETVPIEGSAPKITKPLESVEVNEGEDFDLECVVSGSPSPT- 1124 Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISC 3921 +EW ++ L + +R + D L ED GEY C +N+ G+ T + Sbjct: 1125 -VEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183 Query: 3922 KKL 3924 L Sbjct: 1184 NVL 1186 Score = 60.9 bits (141), Expect = 2e-08 Identities = 36/97 (37%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899 + AP IT L ++ EG + EC + P PN +EWY +G + R T+ D Sbjct: 1664 IGNAPDIITHLISK-EVKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMTTFDG 1720 Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 A++ G D GEY C A N LG A SS RL V Sbjct: 1721 SVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757 Score = 60.9 bits (141), Expect = 2e-08 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 2/93 (2%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 +P +K+ EV EG LE ++ PT+ EWY +G V++ R ++T + G Sbjct: 2256 EPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIAR 2313 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 L I +AED GTY C+ N +G T++ + + Sbjct: 2314 LVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346 Score = 60.5 bits (140), Expect = 3e-08 Identities = 80/285 (28%), Positives = 111/285 (38%), Gaps = 49/285 (17%) Query: 1974 VVEKPQF-GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032 V+ P+F K E TEG LE T+ P +EW+ R + + R Sbjct: 1564 VLTVPEFMDKAEGPIEKTEGDD--LELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRD 1621 Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092 + + +D+G Y C A N G + T + LD Q+ K I Sbjct: 1622 NKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFN-------------LDVQKKKVI---- 1664 Query: 2093 KYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152 G P +T L S E +KEG EC V P I+W+ +G + Sbjct: 1665 -------------GNAPDIITHLISKE-VKEGGTVTLECTVS--GKPAPNIEWYKDGLRF 1708 Query: 2153 RAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKATNKLGEAVNTCTLKVAGHRNIILD 2210 A R TT D G VA + +T A+ D G Y C ATN LG A ++ L V Sbjct: 1709 TATRRVMTTFD-GSVA-SVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVT-------V 1759 Query: 2211 TQHPNGLEKIRQLE-AQGHSTRIEVEEPKISPPRFVTELRGTTHV 2254 P +K+R LE +G + +V P V RGTT + Sbjct: 1760 PSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKPE-VEWYRGTTKI 1803 Score = 60.1 bits (139), Expect = 4e-08 Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 7/195 (3%) Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 G+ VL I T+ D+G Y C A N G E++ K + + P+F + + L Sbjct: 2114 GLFVLTIRNTRPEDAGEYQCIAVN--GAGEVTSKGYLHVEEELTIPQFIGDVPGVVELVQ 2171 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G + ++ ++ P +IEWYHN + + ++R++ + + DSG Y Sbjct: 2172 GDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYR 2229 Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPK 3283 C+A N G + IN K E +P+ ++ ++ +E +G Q + S P Sbjct: 2230 CKAVNTAGTGSKQFNINVQPKRP---EGTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTP 2286 Query: 3284 FITQIQDVTKLVEGQ 3298 + +D ++ E + Sbjct: 2287 TLEWYRDGLRVKESR 2301 Score = 60.1 bits (139), Expect = 4e-08 Identities = 35/105 (33%), Positives = 52/105 (49%), Gaps = 3/105 (2%) Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227 ++ + + +P +Q L P EG+ I +ECR+ +PT + W +G +R K Sbjct: 2542 EVPKPTGEEPTILQRLQ-PVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIK 2598 Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 TY+D L I D G Y A N GSAH+SA + V+ER Sbjct: 2599 TYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLER 2643 Score = 60.1 bits (139), Expect = 4e-08 Identities = 47/183 (25%), Positives = 73/183 (39%), Gaps = 8/183 (4%) Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117 VD EG+ E + +G I W +G +RI+T + + L I K D Sbjct: 2560 VDTIEGEAIKMECRV--SGKPEPTITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGD 2617 Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177 G Y C A N G A S +L +++ +PR +Q+++ G+ A F+ V Sbjct: 2618 EGIYRCNAKNSSGSAHSSAELTVLERE--ARPRILEKLQDVDS-SVGERAMFKIRV--SG 2672 Query: 3178 DPDMKIEWYHNGQPMRHSTR-IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236 P ++WY + + I G+ L I Y D G Y N GE + Sbjct: 2673 SPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLTIEYIDYEDEGAYKAVVINDSGEVSST 2732 Query: 3237 ATI 3239 A + Sbjct: 2733 AVL 2735 Score = 59.3 bits (137), Expect = 8e-08 Identities = 63/221 (28%), Positives = 91/221 (41%), Gaps = 40/221 (18%) Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPK 2098 I+ A D G Y C+ATNA G A + VKV K PK Sbjct: 1331 IVRAKLSDAGVYKCQATNAAGSASRSWEVKV-----------------------KQSAPK 1367 Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158 EE P+ + L + E + EG A+ C+V P +I W +G KIR R Sbjct: 1368 TTGEE-----PIIIRKLQAQE-IDEGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRI 1420 Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV--AGHRNIILDTQHPNG 2216 + D +L I +D G Y TN+ G A +TC + V G R I Sbjct: 1421 KMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIF-----QQK 1475 Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEG 2257 L+ + +E G STR EV+ + P V + ++ +++G Sbjct: 1476 LKAVSTIE--GESTRFEVKLSAMPRPT-VEWFKSSSQIYDG 1513 Score = 58.8 bits (136), Expect = 1e-07 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 7/182 (3%) Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119 + EG + A++ G S + W+ +G+ + S + T L + K D+G Sbjct: 1875 VKEGDDLNISATI--AGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932 Query: 3120 TYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178 +Y C A NK G + ++ + + +GQ P FT+ + +E + +G + Sbjct: 1933 SYKCEANNKLGTVTKTYNVKVMSTAPEGQAPSFTSEMSQVE-VDEGGEVKLYFLISGYPK 1991 Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237 P +K W +G P+ RI S V L I +D G Y C N++G T Sbjct: 1992 PTVK--WTRDGIPVFEDYRISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTV 2049 Query: 3238 TI 3239 + Sbjct: 2050 QV 2051 Score = 58.8 bits (136), Expect = 1e-07 Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P+FI + G +L +G + Y+ +E P +EWY N +++ + R + S A Sbjct: 2157 PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 + + V +DSG Y CKA+N G +NVQ K + S L+ ++ E + Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVEVKEGE 2272 Score = 58.8 bits (136), Expect = 1e-07 Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 4/98 (4%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR--VKTINDFGFV 3615 PEF + + ++E A FE R+ VEW+H +L R ++++ + G+ Sbjct: 2352 PEFKEKLTKVEVTEGDRAKFEVRV--KGYPYPEVEWYHGSNRILDEDRFEIESVKETGYY 2409 Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653 L +G V Q DAG+Y C A N+ G++T L+V RQ Sbjct: 2410 SLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQ 2447 Score = 58.8 bits (136), Expect = 1e-07 Identities = 43/150 (28%), Positives = 70/150 (46%), Gaps = 9/150 (6%) Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088 ++ R E ++P L L+ + I EG++ E RV + + T+T W +G + Sbjct: 2537 FTIRVEVPKPTGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPTIT--WLKDGLVFLT 2593 Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148 NRI+TY D L I V+ D G+Y A+N++G A SA +TV R + Sbjct: 2594 DNRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLEREA------RP 2647 Query: 1149 GLYEKTRHIEESKFVEPMYQIEEISKSKPV 1178 + EK + ++ S M++I PV Sbjct: 2648 RILEKLQDVDSSVGERAMFKIRVSGSPMPV 2677 Score = 58.8 bits (136), Expect = 1e-07 Identities = 56/209 (26%), Positives = 81/209 (38%), Gaps = 13/209 (6%) Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHD----FGFVTLDINSVVANDAGLYMCKAINRAG 2590 +G P+ EWY + E+ G R R D F V+L I V D G Y C A N++G Sbjct: 4229 IGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSG 4288 Query: 2591 XXXXXXXXXXXXXX---XIIDQAMR-PESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTT 2646 I + AM P+S L+ + + G + P F Sbjct: 4289 TDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDIPVAQSTPLKRG--EPPEFIR 4346 Query: 2647 HLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINS 2706 L+ + E + +V R DP EW + +T G R D TL I Sbjct: 4347 KLRD-QFIQEKETARFVCRVIGRPDPTY--EWLRGDKPITDGGRYTIMSDDEGQTLEITD 4403 Query: 2707 LRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 +D G+Y C +TN G +TA + +E Sbjct: 4404 CTVEDEGLYKCVSTNSSGTDTTTARLTVE 4432 Score = 58.4 bits (135), Expect = 1e-07 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 5/125 (4%) Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTM 1075 G K Q D R S + + +P F L ++ EG A FE RV+ Sbjct: 2325 GTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKV-EVTEGDRAKFEVRVKGYP--YP 2381 Query: 1076 TVEWYFNGKQITSANR--IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133 VEWY +I +R I++ + GY +L + V ED+G+Y +A N AG++ A + Sbjct: 2382 EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441 Query: 1134 TVETR 1138 V R Sbjct: 2442 EVNER 2446 Score = 58.4 bits (135), Expect = 1e-07 Identities = 94/403 (23%), Positives = 164/403 (40%), Gaps = 35/403 (8%) Query: 3685 ITIEDEKPNPPRFTV-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 I +E KP T+ + +D EG + +CRV +PT I W +G F T +R Sbjct: 2539 IRVEVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNR 2596 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK--RDIVLESQLPQ 3801 + T D L I + D G Y C A N GSA ++A++T + R +LE +L Sbjct: 2597 IKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLEREARPRILE-KLQD 2655 Query: 3802 GMSGEKIKELERGRISDAP-------KEEPIVSTPPKFITQIK-----SHTVE----ESE 3845 S + + + R+S +P + + ++T +I + + S T+E E E Sbjct: 2656 VDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLTIEYIDYEDE 2715 Query: 3846 GVRFECRV-EPKEDPKLRIEWYRNGKLLPS--GHRYR--TVYDMGFVSLDILYVYAE--D 3898 G + + E + G + PS G + T Y+ + L YV Sbjct: 2716 GAYKAVVINDSGEVSSTAVLRLAEGMIEPSFIGIEFEPITAYEGSDIDL-TFYVKGRPLP 2774 Query: 3899 SGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVY 3958 + E++ V F D T+ T + + + L + R +A+ + +A + + + E+ Sbjct: 2775 TVEFLKDEVPVFKSDRTELTSNGNR-HTLYLSDLAVRDSATYKAVAKNKAGVARRSVEL- 2832 Query: 3959 LTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018 L + + P V ++++ + E + K C++ G P +EW+ + PL Sbjct: 2833 LVKPKRGLKPGEAAPEIVQRLKA-CEVPEGSSFKLRCRV--TGTPTPTIEWYKSNMPLKP 2889 Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061 R + +NF D G Y+ A N G T A Sbjct: 2890 NGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSA 2932 Score = 58.0 bits (134), Expect = 2e-07 Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 3/106 (2%) Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894 +V+V V P F +++ P +++EG A +E R+E +P ++VEW+ ++ RY Sbjct: 1180 EVKVNVLSRPEFKIKMS-PVEVTEGSEAAFEVRVEGFP--KLQVEWFKGMTKIEDSGRYT 1236 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 + D + I V ED+G Y C A N G+ S L V+ +E Sbjct: 1237 FTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKERE 1282 Score = 58.0 bits (134), Expect = 2e-07 Identities = 34/85 (40%), Positives = 47/85 (55%), Gaps = 3/85 (3%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 RP F + ++ + EG A F+ R+ G P L+VEWF+ IEDS R T T D Sbjct: 1188 RPEFKIKMSPVE-VTEGSEAAFEVRV--EGFPKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244 Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459 +M I++V ED G Y C A+N G+ Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGK 1269 Score = 58.0 bits (134), Expect = 2e-07 Identities = 41/167 (24%), Positives = 79/167 (47%), Gaps = 13/167 (7%) Query: 1801 FVQSKASLQLESQ--HESALQKIQQLEDSSRYQRREDVEVAVNQA----PRFITQLNGPT 1854 F+ SKA++ L + +S L + + + + ++ ++ V + P ++ L Sbjct: 2208 FISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKS-V 2266 Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914 ++ EG+ A E + P P + EWY +G ++ R R++ + G A L I + ED Sbjct: 2267 EVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDM 2324 Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 G Y C+ N+LG+ +S LN+ + + + L K++ E D Sbjct: 2325 GTYKCQVRNDLGRTSTSAHLNI----IVATRPEFKEKLTKVEVTEGD 2367 Score = 58.0 bits (134), Expect = 2e-07 Identities = 59/246 (23%), Positives = 100/246 (40%), Gaps = 13/246 (5%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGM 3105 PEF V+++EG A +E + G +EW++ I E I +V G Sbjct: 2352 PEFKEKLTK-VEVTEGDRAKFEVRV--KGYPYPEVEWYHGSNRILDEDRFEIESVKETGY 2408 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDG 3164 L + D+G Y C A NK G++ LE ++ P F T + + +G Sbjct: 2409 YSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQFA--PEFETGEERGPIVVPEG 2466 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 + T+ +P ++ WY +G+ + R+ S L I + DSG Y C Sbjct: 2467 GETTLKVTLRA--NPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKC 2524 Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284 A NK G TI +P L +++ +++++G + S +P Sbjct: 2525 EARNKLGFADKSFTIRVEVPKPT---GEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT 2581 Query: 3285 ITQIQD 3290 IT ++D Sbjct: 2582 ITWLKD 2587 Score = 58.0 bits (134), Expect = 2e-07 Identities = 54/188 (28%), Positives = 79/188 (42%), Gaps = 13/188 (6%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV- 3106 PEF K+I + EG A + + G+ +EWF GK I++ R + Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LKD 3163 L I D GTY C A+N G+ + S +L+ K + P +T + +EG L + Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV--KERMVPPEISTDV--LEGPALLNE 3348 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G +V PD ++WY +G +R ST I S L I D+G Sbjct: 3349 GDDLRLVVSVTGNPIPD--LQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIK 3406 Query: 3224 CRAYNKYG 3231 C A N G Sbjct: 3407 CVAMNPAG 3414 Score = 57.6 bits (133), Expect = 2e-07 Identities = 66/261 (25%), Positives = 109/261 (41%), Gaps = 44/261 (16%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF---G 2033 +P+F +K + EG V L+ + P +EWY + + RFK + G Sbjct: 685 RPEFRTKLKPVKAVEGEEVQLDVKVEGYPKPD--IEWYRGTTMIVESGRFKVMEEEEEDG 742 Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEK 2093 +L I +DTGT ATNA G+A + + +LE Sbjct: 743 LYSLVISKLQLDDTGTIKVVATNASGKATSRA------------------------DLEV 778 Query: 2094 YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR 2153 ER E E + P+ +T EG+ + RV+ +P+ +DWF +G+ I Sbjct: 779 KEREFAPEFEGDEEGPIVVT---------EGNEVSIQLRVKA--NPNADVDWFKDGRPIY 827 Query: 2154 AGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQH 2213 + L I + ED+G Y C+A+N+LG+A + +KV + Sbjct: 828 ESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQVKGP---KGEA 884 Query: 2214 PNGLEKIRQLEA-QGHSTRIE 2233 P L K+R +E +G T+++ Sbjct: 885 PIILSKLRPVETEEGEETKLK 905 Score = 57.6 bits (133), Expect = 2e-07 Identities = 45/149 (30%), Positives = 64/149 (42%), Gaps = 6/149 (4%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836 I+HL + KEG + EC V S P IEW+ + + R +T D S S+ T Sbjct: 1671 ITHLISKEVKEGGTVTLECTV--SGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFT 1728 Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLA 2896 D G Y C ATN GSA +S L T + + Q LE VE +E Sbjct: 1729 DAQGFDDGEYKCVATNPLGSAQSSARLTVT----VPSKPEFKQKLRPLEVVEGSEAKFDV 1784 Query: 2897 KGRRPSVPDTEYPKPEWIIPIAAEHQLVE 2925 + + P+ E+ + I + HQ+ E Sbjct: 1785 RIKSYPKPEVEWYRGTTKITDSLRHQITE 1813 Score = 57.6 bits (133), Expect = 2e-07 Identities = 52/217 (23%), Positives = 90/217 (41%), Gaps = 39/217 (17%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P F + + + +G ++D L G P ++EW+ NE+LI +SR+ + + Sbjct: 2157 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKK--IQKLEQP 2493 + + +V +D G+Y C+A N G I ++ + PEG + + L+ Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAG--------TGSKQFNINVQPKRPEGTEPNIVSGLKSV 2266 Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553 + E+ + EF V++G P+ EWY +G+ +K Sbjct: 2267 EVKEGEQAELEF-------VVSG--------------------TPTPTLEWYRDGLRVKE 2299 Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 R R+T + G L I A D G Y C+ N G Sbjct: 2300 SRRVRSTLENGIARLVITETWAEDMGTYKCQVRNDLG 2336 Score = 57.6 bits (133), Expect = 2e-07 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 11/157 (7%) Query: 923 EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHY 982 EG E R+ + T + WLKDG +RI T+F+ LTI+ V + D G Y Sbjct: 2564 EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIY 2621 Query: 983 TCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQK 1042 C A N+ G A +SA LT++ ++ P LEK+Q ++ S +R +++++ Sbjct: 2622 RCNAKNSSGSAHSSAELTVLERE------ARPRILEKLQDVD--SSVGERAMFKIRVSGS 2673 Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEW 1079 P + ++ + H+ R E + ++T+E+ Sbjct: 2674 PMPVVQWYRRDEEIT-TKGHYIVRDEGRGYFSLTIEY 2709 Score = 57.2 bits (132), Expect = 3e-07 Identities = 67/272 (24%), Positives = 109/272 (40%), Gaps = 43/272 (15%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 ++T+ +E P RF ++K++ V EG V RV G P I+W +G+ + Sbjct: 482 QLTVNEELIGP-RFE-KMKESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNN 537 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803 V T L I+ D+G Y C A NK G+A T ++ K+ P+G Sbjct: 538 VDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKK--------PKGT 589 Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863 + E + EL P+ +T E + C + K P I Sbjct: 590 APEIVSEL-----------RPVEAT--------------EGDDAVLSCTISGKPVP--TI 622 Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKATISC 3921 EW +NG + R + G V L I A+D G+Y C N+ G E TK + Sbjct: 623 EWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIA 682 Query: 3922 KKLPDIILQNQVPRGMKRSEALTQMEATIKKY 3953 P+ + + + ++ E Q++ ++ Y Sbjct: 683 FARPEFRTKLKPVKAVEGEE--VQLDVKVEGY 712 Score = 57.2 bits (132), Expect = 3e-07 Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 3/97 (3%) Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475 +G P L ++E ++EGE A E ++ T P L EWY +G +K R R+ + Sbjct: 2253 EGTEPNIVSGLKSVE-VKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLEN 2309 Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 G L I+ T+ ED G Y C+ N+ G T+A + + Sbjct: 2310 GIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346 Score = 57.2 bits (132), Expect = 3e-07 Identities = 45/137 (32%), Positives = 61/137 (44%), Gaps = 11/137 (8%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836 +S L ++ KEG+ E V + PTL EW+ + + R +ST + L IT Sbjct: 2260 VSGLKSVEVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVIT 2317 Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLA 2896 T+ ED G Y C+ N G +TS L NI T+ P+ K L VE E R Sbjct: 2318 ETWAEDMGTYKCQVRNDLGRTSTSAHL------NIIVATR-PEFKEKLTKVEVTEGDRAK 2370 Query: 2897 KGRRPSVPDTEYPKPEW 2913 R V YP+ EW Sbjct: 2371 FEVR--VKGYPYPEVEW 2385 Score = 56.8 bits (131), Expect = 4e-07 Identities = 57/237 (24%), Positives = 98/237 (41%), Gaps = 13/237 (5%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF---G 3104 PEF T K + + EG+ + + G IEW+ I S R + + G Sbjct: 686 PEFRTKLKPVKAV-EGEEVQLDVKV--EGYPKPDIEWYRGTTMIVESGRFKVMEEEEEDG 742 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 + L I + D+GT ATN G+A LE K + P F + + +G Sbjct: 743 LYSLVISKLQLDDTGTIKVVATNASGKATSRADLEV--KEREFAPEFEGDEEGPIVVTEG 800 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 + V +P+ ++W+ +G+P+ ST+ L I + D+G Y C Sbjct: 801 NEVSIQLRVKA--NPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKC 858 Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281 A N+ G+ + KG + P L+K+R +E+ +G + + T + +P Sbjct: 859 EASNRLGKASRSFDVKVQVKGP---KGEAPIILSKLRPVETEEGEETKLKCTFTGKP 912 Score = 56.8 bits (131), Expect = 4e-07 Identities = 80/353 (22%), Positives = 135/353 (38%), Gaps = 26/353 (7%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P+ + ++K+ V E + CRV P IEWY++ L R + L Sbjct: 2847 PEIVQRLKACEVPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQYFL 2904 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKA------TISCKKLPDIILQNQVPRGMK-RSEA 3942 + L A D G Y+ A N G T A ++S + +V G + R + Sbjct: 2905 NFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVSPPSFRHRLTAVEVDEGDETRFDV 2964 Query: 3943 LTQMEAT-IKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVG 4001 + E T ++ Y + + D ++V + + + + S T + + K L G Sbjct: 2965 RLKKEPTSVEWYKEQQRIFTDGHFEVIEGEEECLYSLVISNTKVADAGGYKCTA-LNESG 3023 Query: 4002 DPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS-------GEYLCRATNLY 4054 + + E N + L+ P D G + G D+ E Sbjct: 3024 KSSTRAELLVNER-LIPPGFEGP--DHGSYELQEGDTITLDAVVKGNPYPEIRWYKDEFL 3080 Query: 4055 GMDETKAVIKTTG-KPGIVYDSQLPKHM---KSIEKIREMEASWQVTPEQVVEESKARCP 4110 M+ K ++ K + +PK K + K + A+ T + ++SK P Sbjct: 3081 AMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKSKGIIP 3140 Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163 F L V+ G ARF C+V+GHP+P++ WL +G + K YDG Sbjct: 3141 EFFRQLRRVEAVQ-GSTARFECKVSGHPEPQIAWLKDGKELAIPRYIKPFYDG 3192 Score = 56.4 bits (130), Expect = 5e-07 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F + + V EG + FE R+E G P +++EW K IE S R+T ++ Sbjct: 1189 PEFKIKMSPVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRYTM 1246 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 + ++ ++D+G Y C A + G ++A L V R Sbjct: 1247 VIANVTLEDAGGYRCVATNTAGKTTSRADLTVKER 1281 Score = 56.4 bits (130), Expect = 5e-07 Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 6/135 (4%) Query: 3821 KEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880 +++ ++ P IT + S V+E V EC V K P IEWY++G + R T Sbjct: 1659 QKKKVIGNAPDIITHLISKEVKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMT 1716 Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKATISCKKLPDIILQNQVPRGMK 3938 +D S+ D GEY C A N G + + T++ P+ + + ++ Sbjct: 1717 TFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSKPEFKQKLRPLEVVE 1776 Query: 3939 RSEALTQMEATIKKY 3953 SEA + + IK Y Sbjct: 1777 GSEA--KFDVRIKSY 1789 Score = 56.4 bits (130), Expect = 5e-07 Identities = 49/190 (25%), Positives = 82/190 (43%), Gaps = 10/190 (5%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 G+ P FT+ V++ EG + + +G ++W +G + +RI + Sbjct: 1960 GQAPSFTSEMSQ-VEVDEG--GEVKLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRV 2016 Query: 3105 MVVLEILGTKTT-DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 V I+ T D G Y C N+ G +V++ +S +P F ++N+EG + Sbjct: 2017 QGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRSI--RPIFGQKMKNVEG-RI 2073 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEY 3222 G+ FE V P + ++ + + R V + G VL I T+ D+GEY Sbjct: 2074 GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEY 2131 Query: 3223 VCRAYNKYGE 3232 C A N GE Sbjct: 2132 QCIAVNGAGE 2141 Score = 56.4 bits (130), Expect = 5e-07 Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 4/95 (4%) Query: 2364 RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS 2423 R E+P+P T + P Q LQ +D I EG+ +CR+ +PT + W ++ + + Sbjct: 2540 RVEVPKP-TGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDN 2595 Query: 2424 RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 RI D ++TI V+ DEG+Y C A N G Sbjct: 2596 RIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSG 2630 Score = 56.4 bits (130), Expect = 5e-07 Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 6/124 (4%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P F Q++ + V+ T +FEC+++ G P ++ W +GK L P YD Sbjct: 3140 PEFFRQLR-RVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCK 3196 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA 4092 + F PED G+Y C A+N G + A + KP ++ + + +K+I+ + EA Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVM--PEFKERLKNIKVVEGDEA 3253 Query: 4093 SWQV 4096 + V Sbjct: 3254 QFSV 3257 Score = 56.4 bits (130), Expect = 5e-07 Identities = 35/100 (35%), Positives = 50/100 (50%), Gaps = 5/100 (5%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRF-RPAYEFDYVA 1369 P+F L NI+ VEG R++ G+ +VEWF GK IK+ RF A E Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409 L + V ED G Y C A+N G+ C+ R+ K+ ++ Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGK--VQCSGRLDVKERMV 3331 Score = 56.4 bits (130), Expect = 5e-07 Identities = 30/91 (32%), Positives = 41/91 (45%) Query: 74 FEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLI 133 F+Q K+ G F+ ++ G P P V W + LVE + +TG SLLI Sbjct: 5009 FQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLI 5068 Query: 134 KQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164 K+ DEG+Y C A N G C + E Sbjct: 5069 KKATLDDEGDYRCVAANPAGTISCQAELLVE 5099 Score = 56.0 bits (129), Expect = 7e-07 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202 + KG +P+ ++ ++ +K+ ++A CT+ P+ EWY + +R S RIK+ Sbjct: 3 RPKGDRPQILQPLEGVD-VKEDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSEV 59 Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240 G L I T+ D GEY C N++G ++A +N Sbjct: 60 VNGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLN 97 Score = 56.0 bits (129), Expect = 7e-07 Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 2/104 (1%) Query: 759 QESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818 ++S + T + P IR LQ E+ EG A+ ++T + P ++W +DG I +SR Sbjct: 1362 KQSAPKTTGEEPIIIRKLQ-AQEIDEGSTANLVCKVT-AAKPEPSIKWTRDGVKIRENSR 1419 Query: 819 ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 I +F+ SL I +D G Y V N+ G A ST + V Sbjct: 1420 IKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLV 1463 Score = 56.0 bits (129), Expect = 7e-07 Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 8/183 (4%) Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118 +I EG A+ + + I+W +G I + RI+ V+ L I D Sbjct: 1383 EIDEGSTANLVCKVTAAKPEPS-IKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDE 1441 Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178 G Y TN++G A + ++ + G +P F ++ + + +G+S FE + + Sbjct: 1442 GVYKVTLTNEYGTASSTCRV--LVNEVGSRPIFQQKLKAVSTI-EGESTRFEVKLSAMPR 1498 Query: 3179 PDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236 P +EW+ + + R I + G VL I T D+G Y AYN G+ ++ Sbjct: 1499 P--TVEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQ 1556 Query: 3237 ATI 3239 A + Sbjct: 1557 ALL 1559 Score = 56.0 bits (129), Expect = 7e-07 Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 8/128 (6%) Query: 2079 TLDEQRLKKIQELEKYERPKP---IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEP 2135 TLD++ + K+ +Y + + G RP+F L ++ + EG+ FE ++ Sbjct: 1437 TLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKLKAVSTI-EGESTRFEVKLSA 1495 Query: 2136 INDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSGTYMCKATNKLGEA 2193 + P T++WF + +I G R+ T + G L I T ED+GTY A N LG+ Sbjct: 1496 M--PRPTVEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKV 1553 Query: 2194 VNTCTLKV 2201 + L+V Sbjct: 1554 TSQALLRV 1561 Score = 56.0 bits (129), Expect = 7e-07 Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 4/100 (4%) Query: 903 PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962 PE T+ P + +K + +KEG A E + G T +EW +DG V+ S R+ + Sbjct: 2252 PEGTE-PNIVSGLKS-VEVKEGEQAELEFVVS--GTPTPTLEWYRDGLRVKESRRVRSTL 2307 Query: 963 NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 G L I D G Y C+ N +G+ +TSA+L I+ Sbjct: 2308 ENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNII 2347 Score = 55.6 bits (128), Expect = 9e-07 Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 5/106 (4%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828 RPQ ++PL+ + +++E NA ++ PT EWY+D + S RI S G Sbjct: 8 RPQILQPLEGV-DVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64 Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTA--SIRVAARSTVTADL 872 +L I RAED G Y N+ G A S A ++RV + + T+ + Sbjct: 65 TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVPVKPSFTSKM 110 Score = 55.6 bits (128), Expect = 9e-07 Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 9/183 (4%) Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117 VD+ E + A ++ +G + EW+ + + S RI++ GM L I T+ D Sbjct: 18 VDVKEDENAILSCTI--SGTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTRAED 75 Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177 G Y C N+ G A L + KP FT+ ++ ++ ++GQ F+ V Sbjct: 76 QGEYKCVLRNEHGTATSKAPL---NVRVPVKPSFTSKMKPVDA-EEGQEVRFDVHVKGSP 131 Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTV-SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236 PD + WY + R + V + V L I+ + D+ Y A N G+ +R Sbjct: 132 KPD--VVWYKGSTMIGTHERFQIVEAAEDHVTLVISEVKLEDAETYKVVATNDVGKVTSR 189 Query: 3237 ATI 3239 A + Sbjct: 190 ADL 192 Score = 55.6 bits (128), Expect = 9e-07 Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 6/101 (5%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK---STFDFG 2698 P F T LK K VEG+ V L+ +VE P+ IEW++ + R K + G Sbjct: 686 PEFRTKLKPV-KAVEGEEVQLDVKVEGYPKPD--IEWYRGTTMIVESGRFKVMEEEEEDG 742 Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHW 2739 L +L I+ L+ DD+G ATN G+A S A +++++R + Sbjct: 743 LYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKEREF 783 Score = 55.6 bits (128), Expect = 9e-07 Identities = 55/221 (24%), Positives = 89/221 (40%), Gaps = 27/221 (12%) Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSL 701 LK VT M G + F R+ + ++W K+ + RF G SL + + Sbjct: 989 LKDVTVMPGEEAEFSIRVSGRAE----VDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDV 1044 Query: 702 NIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQES 761 +D G Y C + +G T+A L I+ PE + + + Sbjct: 1045 RPEDKGTYKCLVFNESGKVTTRAKL------CIKEAIVAPEEVDAAETVP---------- 1088 Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 IE P+ +PL+ + E+ EG + E ++ PT VEW KD + S R+ Sbjct: 1089 IE---GSAPKITKPLESV-EVNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRTSYRLKE 1142 Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 + L R ED G Y +N+ G+A +T ++V Sbjct: 1143 KLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183 Score = 55.6 bits (128), Expect = 9e-07 Identities = 47/168 (27%), Positives = 71/168 (42%), Gaps = 14/168 (8%) Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474 E G P+F L + + EGE+ FE +L+ P VEW+ + + G RF + Sbjct: 1465 EVGSRPIFQQKLKAVSTI-EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEE 1521 Query: 3475 --FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTI 3532 G +L I T ED+G Y AYNN G+ + A ++V ++ + EG I Sbjct: 1522 ENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV---NEVLTVPEFMDKAEGPI 1578 Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECR 3580 +K G LT PE D L ++S +F+ R Sbjct: 1579 EKT------EGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSR 1620 Score = 55.6 bits (128), Expect = 9e-07 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 5/123 (4%) Query: 1820 KIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879 K Q D R + + V P F +L +++EG A +E R++ YP P VE Sbjct: 2328 KCQVRNDLGRTSTSAHLNIIVATRPEFKEKLT-KVEVTEGDRAKFEVRVKGYPYPE--VE 2384 Query: 1880 WYFNGKVLQSGHRYRTSN--DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 WY + R+ + + G+ +L + V ED+G Y C A+N G++ L V Sbjct: 2385 WYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVN 2444 Query: 1938 SKE 1940 ++ Sbjct: 2445 ERQ 2447 Score = 55.2 bits (127), Expect = 1e-06 Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 11/141 (7%) Query: 1820 KIQQLEDSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878 K+ D + R D+ V Q AP FI + GP + G C + P P+ + Sbjct: 176 KVVATNDVGKVTSRADLRVKERQFAPEFIDEERGPIDATTGDEVTLTCSVSGKPKPS--I 233 Query: 1879 EWYFNGKVLQSGHR--YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 WY NGK+L + R+S + + + L+ ED+ Y C+A N LG+A + + V Sbjct: 234 TWYKNGKLLTDSLKLDIRSSGERNWVTM--LSAKPEDTALYKCEAENKLGKASRAFDVKV 291 Query: 1937 QSKE----SIIRDSQHESALE 1953 ++ + S D H A+E Sbjct: 292 KAPKGDAPSFTIDLTHVRAIE 312 Score = 55.2 bits (127), Expect = 1e-06 Identities = 57/231 (24%), Positives = 97/231 (41%), Gaps = 41/231 (17%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP FT+ + +R E + + ++ G P +EWL+ +P+ S R+ T + Sbjct: 298 APSFTIDLTHVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDFEKNVAT 355 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829 L +K D+GTY A N+ G A + + L VQ +++ ++EDS R Sbjct: 356 LVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTK-------------PEIEDSLR 402 Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889 DV + +F ++ G +P P +VEW V++ Sbjct: 403 -----DVSALPGERVKFKVRIGG----------------KPKP----KVEWRKGKSVIED 437 Query: 1890 GHRYRTSNDFG-FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 G R+ + + +L I + D+G Y C A N G+A S +L V + Sbjct: 438 GERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEE 488 Score = 55.2 bits (127), Expect = 1e-06 Identities = 51/195 (26%), Positives = 85/195 (43%), Gaps = 10/195 (5%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV- 3106 PEF + + ++EG L + + ++WF +G+ I S + R + G Sbjct: 785 PEFEGDEEGPIVVTEGN--EVSIQLRVKANPNADVDWFKDGRPIYESTK-RDIKRRGEEH 841 Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEIS--VKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 L I + D+G Y C A+N+ G+A S VK++ V KG+ P + ++ +E ++G Sbjct: 842 TLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQ-VKGPKGEAPIILSKLRPVE-TEEG 899 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 + +CT P EW +G +R S ++ + L I T D G Y C Sbjct: 900 EETKLKCTF--TGKPAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKC 957 Query: 3225 RAYNKYGEDFTRATI 3239 N G T A + Sbjct: 958 TIKNDLGTVSTSAEV 972 Score = 55.2 bits (127), Expect = 1e-06 Identities = 61/245 (24%), Positives = 91/245 (37%), Gaps = 31/245 (12%) Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601 S + + L E E G P D+ + A F R+ V+WF + L Sbjct: 967 STSAEVLVNEVEKGVGPVIEEKLKDVTVMPGEEAEFSIRV----SGRAEVDWFKDEVMLN 1022 Query: 3602 TGSR-VKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660 R + D G L I V D G Y C N G+ T KL +K Sbjct: 1023 DEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIK---------- 1072 Query: 3661 LPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVE 3720 E+I EE + E + IE + P+ T + ++++V EG +C V Sbjct: 1073 ---------EAIVAPEE-VDAAETVPIEG---SAPKITKPL-ESVEVNEGEDFDLECVVS 1118 Query: 3721 PVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780 G P+ ++W + T R+ D L D GEY C N+ G A+ Sbjct: 1119 --GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKAS 1176 Query: 3781 TTAKI 3785 TT ++ Sbjct: 1177 TTGEV 1181 Score = 55.2 bits (127), Expect = 1e-06 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 2/81 (2%) Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765 +V EGG V +C V G P I+W+ +G F RV T D ++ D Sbjct: 1678 EVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDD 1735 Query: 3766 GEYTCRATNKWGSATTTAKIT 3786 GEY C ATN GSA ++A++T Sbjct: 1736 GEYKCVATNPLGSAQSSARLT 1756 Score = 55.2 bits (127), Expect = 1e-06 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 10/137 (7%) Query: 921 IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980 +KEGG E + G +EW KDG A+ R+ T F+ ++T D G Sbjct: 1679 VKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDG 1736 Query: 981 HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKIT 1040 Y C A N +G A +SA LT+ P +K++ LE + + +K Sbjct: 1737 EYKCVATNPLGSAQSSARLTVTV-------PSKPEFKQKLRPLEVVEGSEAKFDVRIKSY 1789 Query: 1041 QKPRFLGPLKGTNKIVE 1057 KP + +GT KI + Sbjct: 1790 PKPE-VEWYRGTTKITD 1805 Score = 55.2 bits (127), Expect = 1e-06 Identities = 31/87 (35%), Positives = 41/87 (47%), Gaps = 2/87 (2%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637 P + LK+VE+KEG++A E + T +EWY + +K R T G L Sbjct: 2257 PNIVSGLKSVEVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVRSTLENGIARL 2314 Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTS 1664 I ED GTY C+ N LG TS Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTS 2341 Score = 55.2 bits (127), Expect = 1e-06 Identities = 33/102 (32%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468 D ++ KG P F L +E + +G A FE +++ +P ++ W +GK L Sbjct: 3129 DVEAKKSKGIIPEFFRQLRRVEAV-QGSTARFECKVSGHPEP--QIAWLKDGKELAIPRY 3185 Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASM 3510 + F D L T PED G+Y C A N GEA + AS+ Sbjct: 3186 IKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASL 3227 Score = 55.2 bits (127), Expect = 1e-06 Identities = 49/163 (30%), Positives = 70/163 (42%), Gaps = 12/163 (7%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P F P+ DQ + EG E R+ VEW KDGR + I T F+ + Sbjct: 3431 PLFIAPLHDQ-EVVEGETIRLECRVR--ATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCT 3487 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028 L IK + D G Y C A N G+ + A LT V + II HP ++ + +E Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRGRSVAQLT-VKEALIIPHFDHP--IQDLDVIE---- 3540 Query: 1029 YSKRTEEEVKITQKPRF-LGPLKGTNKIVEGQSAHFEARVEPQ 1070 R + V+++ KP + LKG ++ G E E Q Sbjct: 3541 -GDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQ 3582 Score = 54.8 bits (126), Expect = 2e-06 Identities = 90/386 (23%), Positives = 157/386 (40%), Gaps = 44/386 (11%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM- 3884 V P F +++K EE + VRF+ V K PK + WY+ ++ + R++ V Sbjct: 100 VPVKPSFTSKMKPVDAEEGQEVRFDVHV--KGSPKPDVVWYKGSTMIGTHERFQIVEAAE 157 Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPRGMKRSE 3941 V+L I V ED+ Y A ND G+ ++A + K+ P+ I + + P + Sbjct: 158 DHVTLVISEVKLEDAETYKVVATNDVGKVTSRADLRVKERQFAPEFIDEERGPIDATTGD 217 Query: 3942 ALT-------QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQ---TSLVEME-- 3989 +T + + +I Y + LT+ D+ +VT + ++ T+L + E Sbjct: 218 EVTLTCSVSGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAE 277 Query: 3990 ------TTKFECQL-APVGD-PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPE 4041 + F+ ++ AP GD P+ ++ + + + + G A W+ E Sbjct: 278 NKLGKASRAFDVKVKAPKGDAPSFTID-LTHVRAIEGEESKLVCKVTGKPAPTIEWLKGE 336 Query: 4042 DSGEYLCRATNLYGMDETKAVIKTT--GKPGIVYDSQLPKHMKSIEKIREMEASWQVTPE 4099 R + + VIK T G G Y + I E+ Sbjct: 337 LPVTTSLRVRTDFEKNVATLVIKDTRLGDAG-TYKVVARNDSGTAHSIAEL--------- 386 Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 QV E S P + SL D V+ GE +F R+ G PKP+V W + I +G R+ + Sbjct: 387 QVQERSTK--PEIEDSLRD-VSALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERFTI 443 Query: 4160 T--YDGMYHFDIPKTRQYDTGKIEVI 4183 D ++ I + D G+ + + Sbjct: 444 AEESDEVFSLIIQDLEETDAGRYKCV 469 Score = 54.8 bits (126), Expect = 2e-06 Identities = 34/94 (36%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167 RP F ++ +E + EG A FE RVE P L ++WF KI RY T D Sbjct: 1188 RPEFKIKMSPVE-VTEGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244 Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + I ED+G Y C ATN G+ + L V Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278 Score = 54.8 bits (126), Expect = 2e-06 Identities = 60/231 (25%), Positives = 97/231 (41%), Gaps = 41/231 (17%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR--TTHDFG 2564 +P F + LT E+ EG A +E RV G P EWY + RF + + G Sbjct: 2351 RPEFKEKLT-KVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETG 2407 Query: 2565 FVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEA 2624 + +L + VV DAG+Y C A +++A + +++ E Sbjct: 2408 YYSLTVGEVVQEDAGMYKCIA---------------------VNKAGKSTCRADLEVNER 2446 Query: 2625 AMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684 PE +TG ++ PI EG L+ + R +P ++ W+K+G Sbjct: 2447 QF--APEF--ETGEERGPIVVP---------EGGETTLKVTL--RANPKPQVIWYKDGKH 2491 Query: 2685 LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 + RL L I + + +DSG Y C+A N LG A + +I++E Sbjct: 2492 TSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADKSFTIRVE 2542 Score = 54.8 bits (126), Expect = 2e-06 Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 8/119 (6%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 + P + L ++T+EG + +ECR+ + T + W +G T +R + ++ D Sbjct: 2549 EEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVC 2606 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427 L + V D G+Y C A N G A +S L V+ ++ P LEK+Q ++ + Sbjct: 2607 TLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLERE------ARPRILEKLQDVDSS 2659 Score = 54.8 bits (126), Expect = 2e-06 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 10/156 (6%) Query: 1835 DVEVAVNQA--PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892 DVE ++ P F QL + +G +A +EC++ +P+P ++ W +GK L Sbjct: 3129 DVEAKKSKGIIPEFFRQLRR-VEAVQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRY 3185 Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952 + D L ED G+YTC A N G+A S L V SK ++ + + L Sbjct: 3186 IKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVM--PEFKERL 3242 Query: 1953 EKIQYLE-DDSRYK-RAVQDDSFVVEKPQFGKPIKN 1986 + I+ +E D++++ R + VE + GK IK+ Sbjct: 3243 KNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKKIKS 3278 Score = 54.8 bits (126), Expect = 2e-06 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 2/108 (1%) Query: 60 PITAGRPGE--PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNK 117 P TA +P + P+F + K+ G A+F+ ++ G PTP V+W R+ + + Sbjct: 5114 PATAPKPAKRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSH 5173 Query: 118 YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165 M+ + SLLI + G D G Y C A+N G+ ++ EG Sbjct: 5174 PHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEG 5221 Score = 54.4 bits (125), Expect = 2e-06 Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 3/97 (3%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP FT L ++ + +EG+ L +V + P IEW K + +TT R+++ F+ + Sbjct: 298 APSFTIDL-THVRAIEGEESKLVCKVTGKPAPT--IEWLKGELPVTTSLRVRTDFEKNVA 354 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 TL I R D+G Y A N G A S A +++++R Sbjct: 355 TLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQER 391 Score = 54.4 bits (125), Expect = 2e-06 Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP +++L P + +EG A C I P P +EW NG ++ R + G Sbjct: 590 APEIVSELR-PVEATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEV 646 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 L I T +D G+YTC N LG A S +L V Sbjct: 647 KLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680 Score = 54.4 bits (125), Expect = 2e-06 Identities = 38/123 (30%), Positives = 56/123 (45%), Gaps = 3/123 (2%) Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTM 1075 G K + + + S E +V + +P F + ++ EG A FE RVE L Sbjct: 1162 GEYKCTVINEHGKASTTGEVKVNVLSRPEFKIKMSPV-EVTEGSEAAFEVRVEGFPKLQ- 1219 Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 VEW+ +I + R D + IA+V ED+G Y VA N AG+ A +TV Sbjct: 1220 -VEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278 Query: 1136 ETR 1138 + R Sbjct: 1279 KER 1281 Score = 54.4 bits (125), Expect = 2e-06 Identities = 39/106 (36%), Positives = 52/106 (49%), Gaps = 5/106 (4%) Query: 765 QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSI 822 + RP F + L+ + + EG + FE +L+ + PT VEW+K I R IT Sbjct: 1465 EVGSRPIFQQKLKAVSTI-EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEE 1521 Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868 N G L I EDAG+Y V A N LG+ S A +RV TV Sbjct: 1522 ENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLTV 1567 Score = 54.4 bits (125), Expect = 2e-06 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 2/93 (2%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P L ++E EG LE + G T +EW+ +G +K R R E L Sbjct: 2257 PNIVSGLKSVEVKEGEQAELEFVVS--GTPTPTLEWYRDGLRVKESRRVRSTLENGIARL 2314 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 + + ED G Y CQ N LG TS L +I Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTSAHLNII 2347 Score = 54.4 bits (125), Expect = 2e-06 Identities = 35/108 (32%), Positives = 53/108 (49%), Gaps = 4/108 (3%) Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873 GR S + IV+T P+F ++ V E + +FE RV K P +EWY + Sbjct: 2336 GRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRV--KGYPYPEVEWYHGSNRIL 2393 Query: 3874 SGHRYR--TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 R+ +V + G+ SL + V ED+G Y C AVN G+ +A + Sbjct: 2394 DEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441 Score = 54.4 bits (125), Expect = 2e-06 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 5/91 (5%) Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR--NEKLIEDSSRITKT 2428 + RP F + L ++ + EG A F+ R+ G P +VEW+ N L ED I Sbjct: 2347 IVATRPEFKEKLTKVE-VTEGDRAKFEVRV--KGYPYPEVEWYHGSNRILDEDRFEIESV 2403 Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 + GY S+T+ V ED G+Y C A N G+ Sbjct: 2404 KETGYYSLTVGEVVQEDAGMYKCIAVNKAGK 2434 Score = 54.0 bits (124), Expect = 3e-06 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 3/98 (3%) Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475 KG P PL ++ ++E ENA ++ T PN EWY + ++ R ++ Sbjct: 5 KGDRPQILQPLEGVD-VKEDENAILSCTISGTPTPN--AEWYRDSIRVRESRRIKSEVVN 61 Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 G L I T ED GEY C N +G A + A + V+ Sbjct: 62 GMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99 Score = 54.0 bits (124), Expect = 3e-06 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 3/81 (3%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 RP QPL+ +D ++E + A C + G PT EW+R+ + +S RI G Sbjct: 8 RPQILQPLEGVD-VKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64 Query: 2435 SMTISHVRDEDEGVYMCRASN 2455 ++TI R ED+G Y C N Sbjct: 65 TLTIKQTRAEDQGEYKCVLRN 85 Score = 54.0 bits (124), Expect = 3e-06 Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 3/94 (3%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP + L+ + EG L + + P IEW KNG+ + R K G V Sbjct: 590 APEIVSELRPVEA-TEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEV 646 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L+I + R DD G YTC N LG A S +K+ Sbjct: 647 KLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680 Score = 54.0 bits (124), Expect = 3e-06 Identities = 40/134 (29%), Positives = 66/134 (49%), Gaps = 7/134 (5%) Query: 3793 IVLESQLPQGMSGEKIKEL-ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG--VRF 3849 +V + P+ + K + E G+ S + + V + P+F +IK VE +EG F Sbjct: 1151 LVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSRPEF--KIKMSPVEVTEGSEAAF 1208 Query: 3850 ECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVND 3909 E RVE PKL++EW++ + RY D ++ I V ED+G Y C A N Sbjct: 1209 EVRVEGF--PKLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNT 1266 Query: 3910 FGEDFTKATISCKK 3923 G+ ++A ++ K+ Sbjct: 1267 AGKTTSRADLTVKE 1280 Score = 54.0 bits (124), Expect = 3e-06 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 3/118 (2%) Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693 V V P F + + + EG E +VE P L++EWFK + R Sbjct: 1181 VKVNVLSRPEFKIKMSPVE-VTEGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDSGRYTF 1237 Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLD 2751 T D T+ I ++ +D+G Y C ATN G+ S A + +++R + D++D Sbjct: 1238 TADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTID 1295 Score = 54.0 bits (124), Expect = 3e-06 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Query: 3274 PSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT 3333 P P P ++ ++ V ++ EG+ A E V P +EW+ +G ++ R R+ Sbjct: 2249 PKRPEGTEPNIVSGLKSV-EVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVRS 2305 Query: 3334 FHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 + GI L I + E+ G Y+C N LGR ST A+L Sbjct: 2306 TLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHL 2344 Score = 54.0 bits (124), Expect = 3e-06 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 5/131 (3%) Query: 1275 IVTDTQNEQ-AIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333 ++T+T E + Q+ D R + +I V P+F L +E EG E R Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVR 2374 Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRF--RPAYEFDYVALDLLSVYPEDSGVYTCQATNQL 1391 ++ G VEW+ I RF E Y +L + V ED+G+Y C A N+ Sbjct: 2375 VK--GYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKA 2432 Query: 1392 GEAVTSCALRV 1402 G++ L V Sbjct: 2433 GKSTCRADLEV 2443 Score = 54.0 bits (124), Expect = 3e-06 Identities = 59/219 (26%), Positives = 87/219 (39%), Gaps = 41/219 (18%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGF 3752 P F ++ ++V EG F+ RV+ G P ++W+H R + ++ + G+ Sbjct: 2352 PEFKEKLT-KVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETGY 2408 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812 +L + + DAG Y C A NK G K TC A ++ P+ +GE E Sbjct: 2409 YSLTVGEVVQEDAGMYKCIAVNKAG------KSTCRADLEVNERQFAPEFETGE-----E 2457 Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872 RG PIV P EG +V + +PK ++ WY++GK Sbjct: 2458 RG---------PIV-VP---------------EGGETTLKVTLRANPKPQVIWYKDGKHT 2492 Query: 3873 PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 R L I EDSG Y C A N G Sbjct: 2493 SENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLG 2531 Score = 54.0 bits (124), Expect = 3e-06 Identities = 37/129 (28%), Positives = 67/129 (51%), Gaps = 7/129 (5%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 PEF ++ ++ +G A FE ++ G ++ WLKDG+ + I F++ Sbjct: 3140 PEFFRQLR-RVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCK 3196 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE-DAS 1027 LT D G YTC A N G+A++ A+L +++K ++ E + L+ I+ +E D + Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVMPEFKE--RLKNIKVVEGDEA 3253 Query: 1028 RYSKRTEEE 1036 ++S R + E Sbjct: 3254 QFSVRVKGE 3262 Score = 54.0 bits (124), Expect = 3e-06 Identities = 34/85 (40%), Positives = 47/85 (55%), Gaps = 4/85 (4%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT-KTHDFGYV 2434 P F + L+NI + EG A F R+ G+P KVEWF+ K I+ +R + K + Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459 ++TIS V ED G Y C ASN G+ Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGK 3317 Score = 53.6 bits (123), Expect = 4e-06 Identities = 60/237 (25%), Positives = 101/237 (42%), Gaps = 38/237 (16%) Query: 2224 EAQGHSTRIEV-EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282 E+ STR E+ ++ PP F G+ + EG T + V+ +P I +Y + Sbjct: 3021 ESGKSSTRAELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVKG--NPYPEIRWYKDE 3078 Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIIS 2342 + + ++ SL + H +P+D+G Y N +G T S TV Sbjct: 3079 FLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATK--SFTVDV------ 3130 Query: 2343 ESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIP 2402 E+++ +G+ IPE F + L+ ++ +Q G TA F+C++ Sbjct: 3131 EAKKSKGI----------------IPE--------FFRQLRRVEAVQ-GSTARFECKVS- 3164 Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 G P ++ W ++ K + I +D +T + EDEG Y C ASN GE Sbjct: 3165 -GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGE 3220 Score = 53.6 bits (123), Expect = 4e-06 Identities = 36/97 (37%), Positives = 48/97 (49%), Gaps = 4/97 (4%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV- 1101 P F LK K+VEG A F RV+ + + VEW+ GK+I S R + + Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRVKGEPE--PKVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 L I+ V ED G Y VA N AG+ Q S + V+ R Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329 Score = 53.6 bits (123), Expect = 4e-06 Identities = 36/162 (22%), Positives = 72/162 (44%), Gaps = 4/162 (2%) Query: 198 TEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLRE--VSFRESITKRYVGESDVQISTE 255 T++ R +GTD SS + + ++E +S +S + + D+ ++ Sbjct: 4274 TDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDIPVAQS 4333 Query: 256 IDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEII 315 G PP+ +K R+ +QE A+F ++ G P P W + + + + ++ I+ Sbjct: 4334 TPLKRG--EPPEFIRKLRDQFIQEKETARFVCRVIGRPDPTYEWLRGDKPITDGGRYTIM 4391 Query: 316 TTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 + TL + + D G Y ++ N +G T+ L VE+ Sbjct: 4392 SDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEA 4433 Score = 53.6 bits (123), Expect = 4e-06 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 68 EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127 E P+F Q + R +G A+F K+ G+P P V W + + E ++ + + G Sbjct: 4513 ESGEPVFVQKPETCRLKEGDTARFNVKVNGSPEPFVDWFLGRRMIEEDDRIRIEEGD-VG 4571 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157 + SL+I I D G Y C A N G C Sbjct: 4572 ECSLVIMDIDREDAGVYKCVAENDDGSISC 4601 Score = 53.2 bits (122), Expect = 5e-06 Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 12/131 (9%) Query: 2232 IEVEEPKI--SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA 2289 ++V++ K+ + P +T L + V EG T EC V PN IE+Y +G + Sbjct: 1656 LDVQKKKVIGNAPDIITHLI-SKEVKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATR 1712 Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG 2349 R TFD S+ D GEY A N LG S+ +TVT +PE Sbjct: 1713 RVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTV-------PSKPEF 1765 Query: 2350 LEKIRELESAE 2360 +K+R LE E Sbjct: 1766 KQKLRPLEVVE 1776 Score = 53.2 bits (122), Expect = 5e-06 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 4/122 (3%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601 I + + G + QV D + + ++ + P L VE+ EG RA FE R+ Sbjct: 2316 ITETWAEDMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRV 2375 Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 +VEWYH + + RF G+ +L + + ED+G Y C A+N G Sbjct: 2376 --KGYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAG 2433 Query: 1660 EA 1661 ++ Sbjct: 2434 KS 2435 Score = 53.2 bits (122), Expect = 5e-06 Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 6/124 (4%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F ++ + + A FE ++ G P+ ++ WL++G + + +D L Sbjct: 3140 PEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKL 3197 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE-DSSR 1829 PED G YTC A NE GEA + ++L V SK + E + L+ I+ +E D ++ Sbjct: 3198 TFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVMPE--FKERLKNIKVVEGDEAQ 3254 Query: 1830 YQRR 1833 + R Sbjct: 3255 FSVR 3258 Score = 52.8 bits (121), Expect = 7e-06 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 2/123 (1%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E P+F + + + +G +++ LE G +EW + R + A+SR+ Sbjct: 2150 VEEELTIPQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLS 2207 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021 F + + +VT+ D+G Y C+A N G + N+ + K+ E GL+ ++ Sbjct: 2208 FISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVE 2267 Query: 1022 YLE 1024 E Sbjct: 2268 VKE 2270 Score = 52.4 bits (120), Expect = 9e-06 Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 3/106 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+ + L+ V A EG I G P IEWLKNG ++ S R G + L Sbjct: 591 PEIVSELRPVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKL 648 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE-RTSQHP 741 + + D G+YTC + G AE+K L V A E RT P Sbjct: 649 TIKTTRADDQGDYTCIVRNELGSAESKTKLKVIAFARPEFRTKLKP 694 Score = 52.4 bits (120), Expect = 9e-06 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248 V EG + LEC + G P +EW+ +G T R T +D ++ A D G Sbjct: 1679 VKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDG 1736 Query: 1249 EYTVRAVNHLGSAHTSAIVRV 1269 EY A N LGSA +SA + V Sbjct: 1737 EYKCVATNPLGSAQSSARLTV 1757 Score = 52.4 bits (120), Expect = 9e-06 Identities = 40/167 (23%), Positives = 69/167 (41%), Gaps = 8/167 (4%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 TG + IEW+ + ++ + R+ + L L T+ D G Y A N G + Sbjct: 2871 TGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLG--SV 2928 Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194 S E + + P F + +E + +G F+ V + +EWY Q + Sbjct: 2929 STSAELIIEPSVSPPSFRHRLTAVE-VDEGDETRFD---VRLKKEPTSVEWYKEQQRIFT 2984 Query: 3195 STRIKTV--SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239 + + + L I+ T+ D+G Y C A N+ G+ TRA + Sbjct: 2985 DGHFEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL 3031 Score = 52.4 bits (120), Expect = 9e-06 Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 3/96 (3%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY-IS 695 P+F LK++ +EG + F R++ G+P K+EW K G+ I++ +RF+S + + Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 L + + ++D G Y C A + G + L V R Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329 Score = 52.4 bits (120), Expect = 9e-06 Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 4/94 (4%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV- 967 PEFK +K+ I + EG A F R++ G+ +VEW K G+ +++ +R ++ + Sbjct: 3236 PEFKERLKN-IKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 LTI V + D G Y C A N G+ S L + Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV 3326 Score = 52.4 bits (120), Expect = 9e-06 Identities = 43/154 (27%), Positives = 64/154 (41%), Gaps = 9/154 (5%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P F P+ + EV EG + LE + P VEW +GR ++ + T +D + L Sbjct: 3431 PLFIAPLHDQEVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYTEFDGQHCTL 3488 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097 I A ED G Y C A N G + + + V K L + D IQ+L+ E Sbjct: 3489 VIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV--KEALIIPHFDH----PIQDLDVIEGD 3542 Query: 2098 K-PIEEEQPGQRPVFLTALTSLENLKEGDRAHFE 2130 + E G+ + L + L+ G R E Sbjct: 3543 RAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLE 3576 Score = 52.0 bits (119), Expect = 1e-05 Identities = 90/427 (21%), Positives = 167/427 (39%), Gaps = 40/427 (9%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 ++ ++ K + P FT+++ ++ EG C+V G P I+W P T R Sbjct: 288 DVKVKAPKGDAPSFTIDLT-HVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLR 344 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC---SAKRDIVLESQLP 3800 V T + L I DAG Y A N G+A + A++ S K +I + Sbjct: 345 VRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTKPEIEDSLRDV 404 Query: 3801 QGMSGEKIKELERGRISDAPKEE-----PIVSTPPKFITQIKSHTV--------EESEGV 3847 + GE++K R PK E ++ +F +S V EE++ Sbjct: 405 SALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAG 464 Query: 3848 RFEC-RVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906 R++C + + + N +L+ G R+ + + V +S E + R Sbjct: 465 RYKCVATNEAGEAESMAQLTVNEELI--GPRFEKMKES-------FTVVEGESVELVARV 515 Query: 3907 VNDFGE--DFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDL 3964 ++TK + +K ++ + + + + E ++ ++ + + T+ D+ Sbjct: 516 TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADM 575 Query: 3965 ---YDVDKKQPPRFVTQIQSQTSLVEM---ETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018 DV K+P +I S+ VE + C ++ G P +EW NG + Sbjct: 576 TFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKD 633 Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP 4078 R G V + +D G+Y C N G E+K +K + ++L Sbjct: 634 SRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIAFARPEFRTKL- 692 Query: 4079 KHMKSIE 4085 K +K++E Sbjct: 693 KPVKAVE 699 Score = 52.0 bits (119), Expect = 1e-05 Identities = 35/113 (30%), Positives = 52/113 (46%), Gaps = 3/113 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-S 695 P+ L+ V+A+ G ++ F+ RI G P K+EW K IE RFT + S Sbjct: 395 PEIEDSLRDVSALPGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEVFS 452 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ 748 L + L D+G Y C A + G AE+ A L V R + E+ ++ Sbjct: 453 LIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEELIGPRFEKMKESFTVVE 505 Score = 52.0 bits (119), Expect = 1e-05 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 2/95 (2%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP+ L +E EG + L C + G +EW NG +K R + V Sbjct: 590 APEIVSELRPVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVK 647 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404 L + + +D G YTC N+LG A + L+VIA Sbjct: 648 LTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIA 682 Score = 52.0 bits (119), Expect = 1e-05 Identities = 44/147 (29%), Positives = 69/147 (46%), Gaps = 13/147 (8%) Query: 1528 DEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTD--MVDEVTTQAPICTTSLK 1585 D +C LT R +T ++ G+ ++ + + T +V+EV ++ PI LK Sbjct: 1425 DGETCSLTIRD------ATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSR-PIFQQKLK 1477 Query: 1586 NVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT--ETNNFGFVALDIMSCL 1643 V EG+ FE +L + T VEW+ ++ + G RFT E N G L I Sbjct: 1478 AVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTN 1535 Query: 1644 PEDSGTYTCRAINALGEAVTSGIAIVH 1670 ED+GTY A N LG+ + + V+ Sbjct: 1536 IEDAGTYKVVAYNNLGKVTSQALLRVN 1562 Score = 52.0 bits (119), Expect = 1e-05 Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 2/106 (1%) Query: 1968 VQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK 2027 VQ + P + + EV EG V LE T++ P +EWY +G R Sbjct: 1658 VQKKKVIGNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVM 1715 Query: 2028 TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 TT+D ++ A D G Y C ATN +G A +++ + V S Sbjct: 1716 TTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPS 1761 Score = 52.0 bits (119), Expect = 1e-05 Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 PQFI + V + G +++ +E G P +IEW N + I A+SR F ++ Sbjct: 2157 PQFIGDVPGVVELVQGD-NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATI 2215 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 + ++ + DSG Y C+AV+ G + ++V P+ Sbjct: 2216 ALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK 2250 Score = 52.0 bits (119), Expect = 1e-05 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 3/93 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P + L+ + E++EG A E ++ PT+ EWY+DG + S R+ S G Sbjct: 2257 PNIVSGLKSV-EVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIAR 2313 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 L I AED G+Y + N LG ++A + + Sbjct: 2314 LVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346 Score = 52.0 bits (119), Expect = 1e-05 Identities = 36/99 (36%), Positives = 47/99 (47%), Gaps = 5/99 (5%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIFNFG 826 RP+F L + E+ EG A FE ++ P VEWY I R I S+ G Sbjct: 2351 RPEFKEKLTKV-EVTEGDRAKFEVRVKGYPYP--EVEWYHGSNRILDEDRFEIESVKETG 2407 Query: 827 YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 Y SL + + EDAG Y AVNK G++ A + V R Sbjct: 2408 YYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446 Score = 52.0 bits (119), Expect = 1e-05 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 5/106 (4%) Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877 +A K + I+ P+F Q++ + RFEC+V +P+ I W ++GK L Sbjct: 3131 EAKKSKGII---PEFFRQLRRVEAVQGSTARFECKVSGHPEPQ--IAWLKDGKELAIPRY 3185 Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 + YD L ED G+Y C A N+ GE + A++ K Sbjct: 3186 IKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASLVLSK 3231 Score = 52.0 bits (119), Expect = 1e-05 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+F Q++ V + V+G +A FE ++ P+ ++ W +GK+L + F+D + Sbjct: 3140 PEFFRQLRRV-EAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCK 3196 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372 L E+ G+Y CVA+N+ G S+ A+L Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL 3227 Score = 52.0 bits (119), Expect = 1e-05 Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 3/96 (3%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV-A 1769 P F +K+I+V E A F R+ G+P+ +VEW + G I++ R ++ + Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 L + V ED GTY C A N+ G+ S L V+ + Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329 Score = 52.0 bits (119), Expect = 1e-05 Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 3/106 (2%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP F LH+ E VEG + LECR++ VEW +G+ K + ++ + Sbjct: 3430 APLFIAPLHDQEVVEGETIRLECRVR--ATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCT 3487 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415 L + ED G Y C A N+ G S A + + +I HP Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRG-RSVAQLTVKEALIIPHFDHP 3532 Score = 51.6 bits (118), Expect = 2e-05 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 6/123 (4%) Query: 1026 ASRYSKRTEEEVKITQKPRFLGP----LKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081 A+ + E ++T +GP +K + +VEG+S ARV + +EW Sbjct: 470 ATNEAGEAESMAQLTVNEELIGPRFEKMKESFTVVEGESVELVARVTGKP--APEIEWTK 527 Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141 +GK + N + T L I +DSG+Y ARN +G A ++ + V+ + Sbjct: 528 DGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPK 587 Query: 1142 DTS 1144 T+ Sbjct: 588 GTA 590 Score = 51.6 bits (118), Expect = 2e-05 Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 4/121 (3%) Query: 1954 KIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW 2013 K Q D R + + V +P+F + + EVTEG E + P VEW Sbjct: 2328 KCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGY--PYPEVEW 2385 Query: 2014 YCNGRPVQQGHRFK--TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071 Y + RF+ + + GY +L + ED G Y C A N G++ + ++V+ Sbjct: 2386 YHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNE 2445 Query: 2072 K 2072 + Sbjct: 2446 R 2446 Score = 51.6 bits (118), Expect = 2e-05 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 4/107 (3%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR-ITSIFNFGY 827 RP+ + LQD+ + G A F+ +++ P V+WY+ IT I GY Sbjct: 2646 RPRILEKLQDV-DSSVGERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGY 2702 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874 SL I ++ ED G+Y +N GE STA +R+A + +GI Sbjct: 2703 FSLTIEYIDYEDEGAYKAVVINDSGEVSSTAVLRLAEGMIEPSFIGI 2749 Score = 51.6 bits (118), Expect = 2e-05 Identities = 33/121 (27%), Positives = 52/121 (42%), Gaps = 13/121 (10%) Query: 50 TQVESSGDRQPITAGRPGEPSP------------PIFEQIFKNARFAQGGNAKFEGKLRG 97 TQ E GD + + GE S P F++ KN + +G A+F +++G Sbjct: 3202 TQPEDEGDYTCVASNEAGEASSHASLVLSKPLVMPEFKERLKNIKVVEGDEAQFSVRVKG 3261 Query: 98 NPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157 P P V W + + ++S + E+ +L I + D G Y C A N G+ C Sbjct: 3262 EPEPKVEWFKTGKKIKSHARFSSKAGEK-HTYTLTISDVAMEDFGTYKCVASNDAGKVQC 3320 Query: 158 S 158 S Sbjct: 3321 S 3321 Score = 51.6 bits (118), Expect = 2e-05 Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 3/89 (3%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SLD 2834 F L NI EGD F V+ +P K+EWF K + S R+ S + +L Sbjct: 3238 FKERLKNIKVVEGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKHTYTLT 3295 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 I+ ED G Y C A+N G SG L Sbjct: 3296 ISDVAMEDFGTYKCVASNDAGKVQCSGRL 3324 Score = 51.2 bits (117), Expect = 2e-05 Identities = 53/197 (26%), Positives = 85/197 (43%), Gaps = 38/197 (19%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 +EWLK+G V+ S R G V LTIK+ D G YTC N +G A + L ++ Sbjct: 622 IEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVI 681 Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPR-FLGPLKGTNKIVEGQSA 1061 A + L+ ++ +E + + +VK+ P+ + +GT IVE S Sbjct: 682 A----FARPEFRTKLKPVKAVE-----GEEVQLDVKVEGYPKPDIEWYRGTTMIVE--SG 730 Query: 1062 HFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVAR 1121 F+ E + D G +L I+ ++ +D+G VVA Sbjct: 731 RFKVMEEEEED--------------------------GLYSLVISKLQLDDTGTIKVVAT 764 Query: 1122 NAAGEAQLSASMTVETR 1138 NA+G+A A + V+ R Sbjct: 765 NASGKATSRADLEVKER 781 Score = 51.2 bits (117), Expect = 2e-05 Identities = 58/213 (27%), Positives = 83/213 (38%), Gaps = 27/213 (12%) Query: 2523 GQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRF-RTTHDFGFVTLDINSVVANDAGLY 2581 G+ A + RV +W+ + V L RF D G +L I+ V D G Y Sbjct: 997 GEEAEFSIRV----SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTY 1052 Query: 2582 MCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQA 2641 C N +G I + + PE + A VP ++ A Sbjct: 1053 KCLVFNESGKVTTRAKLC------IKEAIVAPEEVD-------AAETVP---IEGS---A 1093 Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P T L+S + + EG+ LE V P +EW K+ V L T RLK D + Sbjct: 1094 PKITKPLESVE-VNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRTSYRLKEKLDGNVAK 1150 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L R +D G Y C N G+A +T +K+ Sbjct: 1151 LVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183 Score = 51.2 bits (117), Expect = 2e-05 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 9/131 (6%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566 +P F ++ P E+ EG A +E RV G P L+ EW+ +++ R+ T D Sbjct: 1188 RPEF-KIKMSPVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244 Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAM 2626 T+ I +V DAG Y C A N AG + ++ PE + ++ + Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAG------KTTSRADLTVKEREFAPEFETRDDTIDSEV 1298 Query: 2627 NKVPEMFVDTG 2637 NK E+ V TG Sbjct: 1299 NKEVEIKVTTG 1309 Score = 51.2 bits (117), Expect = 2e-05 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 3/97 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+F ++ V ++ EG A FE R+ P L+VEWF K+ RY D Sbjct: 1189 PEFKIKMSPV-EVTEGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDSGRYTFTADKNRYT 1245 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 + I E++G Y CVATN G+ +++A+L +E Sbjct: 1246 MVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKERE 1282 Score = 51.2 bits (117), Expect = 2e-05 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P +K + V E + A E + G P +EW R+G+ ++ S R+ + + G L Sbjct: 2257 PNIVSGLKSVEVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVRSTLENGIARL 2314 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800 + ED GTY C+ N+LG TS+ L Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTSAHL 2344 Score = 51.2 bits (117), Expect = 2e-05 Identities = 40/130 (30%), Positives = 61/130 (46%), Gaps = 15/130 (11%) Query: 2907 EYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962 E PKP P + +EG+ + +E +V K +P I W +G V +R K Sbjct: 2542 EVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKT 2599 Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022 D TL + DV D GIY C A N G A +S+ + ++ER P+ L Sbjct: 2600 YFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAEL------TVLEREARPR---IL 2650 Query: 3023 EKIQNLEDSL 3032 EK+Q+++ S+ Sbjct: 2651 EKLQDVDSSV 2660 Score = 51.2 bits (117), Expect = 2e-05 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 4/102 (3%) Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744 + IE +KP P F + D +V EG + +CRV P ++W +GR F + Sbjct: 3422 VVIESKKP-APLFIAPLHDQ-EVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHI 3477 Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786 +T D L I D G Y C A NK G + A++T Sbjct: 3478 YTEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLT 3519 Score = 51.2 bits (117), Expect = 2e-05 Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 3/96 (3%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP+F L + +VEG+ + LE +V R P +EW K+G T + + FD Sbjct: 3430 APLFIAPLHDQE-VVEGETIRLECRV--RATPRPMVEWKKDGRTFKEDYHIYTEFDGQHC 3486 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 TL I + +D G Y C A N G S A + +++ Sbjct: 3487 TLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKE 3522 Score = 51.2 bits (117), Expect = 2e-05 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 2/94 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P FI + V E E +R ECRV + P+ +EW ++G+ + T +D +L Sbjct: 3431 PLFIAPLHDQEVVEGETIRLECRV--RATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCTL 3488 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 I ED G Y C A N G + A ++ K+ Sbjct: 3489 VIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKE 3522 Score = 50.8 bits (116), Expect = 3e-05 Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFG 2432 RP+F Q L+ + I EG++ F+ +L + PT VEWF++ I D R IT+ + G Sbjct: 1469 RPIFQQKLKAVSTI-EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSG 1525 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459 + I ED G Y A N LG+ Sbjct: 1526 VYVLVIEDTNIEDAGTYKVVAYNNLGK 1552 Score = 50.8 bits (116), Expect = 3e-05 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 2/86 (2%) Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840 E++EG E ++ P +EWYKDG TA+ R+ + F+ S+ + D Sbjct: 1678 EVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDD 1735 Query: 841 GSYTVRAVNKLGEAISTASIRVAARS 866 G Y A N LG A S+A + V S Sbjct: 1736 GEYKCVATNPLGSAQSSARLTVTVPS 1761 Score = 50.8 bits (116), Expect = 3e-05 Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 4/97 (4%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS-TFDFGLV 2700 P F LK+ K+VEG +V+ +P K+EWFK G + + AR S + Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 TL+I+ + +D G Y C A+N G+ + + +++R Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329 Score = 50.8 bits (116), Expect = 3e-05 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 10/88 (11%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT----FHDF 3337 P+F +++++ K+VEG A F R+ +P+ KVEWF GKK+ R+ + H + Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 3338 GIVILDILYCYEENSGEYECVATNKLGR 3365 + I D+ E+ G Y+CVA+N G+ Sbjct: 3293 TLTISDVAM---EDFGTYKCVASNDAGK 3317 Score = 50.8 bits (116), Expect = 3e-05 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 2/95 (2%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ--TG 127 SPP F++ K G K + G+PTPV+ W + ++E + +++ Sbjct: 4203 SPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFT 4262 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162 VSL I+ + DEG Y C A+N+ G S ++ Sbjct: 4263 IVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVK 4297 Score = 50.4 bits (115), Expect = 3e-05 Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843 EG + ++T PT +EW K P+T S R+ + F +L I R DAG+Y Sbjct: 312 EGEESKLVCKVTGKPAPT--IEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTY 369 Query: 844 TVRAVNKLGEAISTASIRVAARST 867 V A N G A S A ++V RST Sbjct: 370 KVVARNDSGTAHSIAELQVQERST 393 Score = 50.4 bits (115), Expect = 3e-05 Identities = 51/192 (26%), Positives = 78/192 (40%), Gaps = 21/192 (10%) Query: 2011 VEWYCNGRPVQQGHRF-KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 V+W+ + + RF D G +L I ED GTY C N G+ T + + + Sbjct: 1012 VDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI 1071 Query: 2070 DAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHF 2129 ++ + +E++ E PIE G P L S+E + EG+ Sbjct: 1072 ------------KEAIVAPEEVDAAETV-PIE----GSAPKITKPLESVE-VNEGEDFDL 1113 Query: 2130 ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNK 2189 EC V P T++W + K+R +R + D L ED G Y C N+ Sbjct: 1114 ECVVS--GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINE 1171 Query: 2190 LGEAVNTCTLKV 2201 G+A T +KV Sbjct: 1172 HGKASTTGEVKV 1183 Score = 50.4 bits (115), Expect = 3e-05 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288 ST EV+ +S P F ++ V EG A FE +VE P L++E++ ++ + Sbjct: 1176 STTGEVKVNVLSRPEFKIKM-SPVEVTEGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDS 1232 Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 R+ T D ++ I + EDAG Y A N G TS +TV Sbjct: 1233 GRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278 Score = 50.4 bits (115), Expect = 3e-05 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 3/93 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P + LKS + + EG+ LE V P L EW+++G+ + R++ST + G+ Sbjct: 2257 PNIVSGLKSVE-VKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIAR 2313 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L I +D G Y C+ N LG ++A + I Sbjct: 2314 LVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346 Score = 50.4 bits (115), Expect = 3e-05 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 3/91 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+F R L+ + E +G A FE +++ +P ++ W KDG+ + I ++ Sbjct: 3140 PEFFRQLRRV-EAVQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYIKPFYDGEVCK 3196 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860 L + ED G YT A N+ GEA S AS+ Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL 3227 Score = 50.4 bits (115), Expect = 3e-05 Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 4/97 (4%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT-SNDFGFA 1902 P F +L K+ EG A + R++ P+P +VEW+ GK ++S R+ + + + Sbjct: 3236 PEFKERLKN-IKVVEGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 L I V ED G Y C A N+ G+ S RL+V+ + Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329 Score = 50.4 bits (115), Expect = 3e-05 Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 3/104 (2%) Query: 3410 TSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRF 3469 T V E K AP+F PL + E + EGE E R+ T P VEW +G++ K Sbjct: 3421 TVVIESKKPAPLFIAPLHDQEVV-EGETIRLECRVRATPRP--MVEWKKDGRTFKEDYHI 3477 Query: 3470 RTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 T D L I ED G Y C A N G + A + V+ Sbjct: 3478 YTEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK 3521 Score = 50.4 bits (115), Expect = 3e-05 Identities = 34/99 (34%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823 E P FI PL D E+ EG E ++ + P VEW KDGR I + F Sbjct: 3425 ESKKPAPLFIAPLHDQ-EVVEGETIRLECRVR--ATPRPMVEWKKDGRTFKEDYHIYTEF 3481 Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 + + +L I + ED G+Y A NK G S A + V Sbjct: 3482 DGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV 3520 Score = 50.0 bits (114), Expect = 5e-05 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 ++PQ +P++ +V E L T++ PT EWY + V++ R K+ G Sbjct: 7 DRPQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 L I AED G Y C N G A + + + V Sbjct: 65 TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98 Score = 50.0 bits (114), Expect = 5e-05 Identities = 31/94 (32%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P+ + L G + E ++A C I P PN EWY + ++ R ++ G A Sbjct: 9 PQILQPLEG-VDVKEDENAILSCTISGTPTPN--AEWYRDSIRVRESRRIKSEVVNGMAT 65 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 L I ED GEY C N G A S LNV+ Sbjct: 66 LTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99 Score = 50.0 bits (114), Expect = 5e-05 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP ++ + E A + G P +EWL+NG+ ++ S R G V Sbjct: 590 APEIVSELRPVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVK 647 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 L +K +D G YTC NELG A + + L V Sbjct: 648 LTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680 Score = 50.0 bits (114), Expect = 5e-05 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP+ ++ L ++E EG + LEC + G + VEW + ++T +R + + + Sbjct: 1093 APKITKPLESVEVNEGEDFDLECVVS--GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAK 1150 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L PED G Y C N+ G+A T+ ++V Sbjct: 1151 LVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183 Score = 50.0 bits (114), Expect = 5e-05 Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 8/142 (5%) Query: 1024 EDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNG 1083 E S+ EEE+ I P+F+G + G ++V+G + ++ +E + +EWY N Sbjct: 2141 EVTSKGYLHVEEELTI---PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNE 2195 Query: 1084 KQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143 + I + +R+Q + + +V +DSG+Y A N AG ++ V+ + T Sbjct: 2196 RLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGT 2255 Query: 1144 S-SIHRGLYEKTRHIEESKFVE 1164 +I GL K+ ++E + E Sbjct: 2256 EPNIVSGL--KSVEVKEGEQAE 2275 Score = 50.0 bits (114), Expect = 5e-05 Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P F + +LV+G + L +V R P +IEW+ N + +R++ +F T Sbjct: 2157 PQFIGDVPGVVELVQGDNYDLSLEV--RGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 +++ ++ DDSG+Y CKA N G +I ++ + Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK 2250 Score = 50.0 bits (114), Expect = 5e-05 Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 5/96 (5%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFFNFG 965 +PEFK + ++ + EG A FE R++ G VEW + R I + G Sbjct: 2351 RPEFKEKLT-KVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETG 2407 Query: 966 YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 Y +LT+ V DAG Y C A N G++T A+L + Sbjct: 2408 YYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEV 2443 Score = 50.0 bits (114), Expect = 5e-05 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 4/97 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT--SIFRFGYI 694 P+F L V EG + FE R++ G P ++EW I RF S+ GY Sbjct: 2352 PEFKEKLTKVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETGYY 2409 Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 SL + + +D+G Y C AV+ G + +A L V R Sbjct: 2410 SLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446 Score = 50.0 bits (114), Expect = 5e-05 Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 10/141 (7%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 + P ++ + E +A E R+ G P+ + WL++G+ NR+ T D Sbjct: 2549 EEPTILQRLQPVDTIEGEAIKMECRVS--GKPEPTITWLKDGLVFLTDNRIKTYFDGDVC 2606 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828 L ++ V D G Y C A N G A +S+ L V L+ E++ L+K+Q ++ S Sbjct: 2607 TLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTV-----LEREAR-PRILEKLQDVDSS- 2659 Query: 1829 RYQRREDVEVAVNQAPRFITQ 1849 R ++ V+ +P + Q Sbjct: 2660 -VGERAMFKIRVSGSPMPVVQ 2679 Score = 50.0 bits (114), Expect = 5e-05 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-S 695 P+F L+ V A++G FE ++ G P +I WLK+G+ + A R+ F G + Sbjct: 3140 PEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKEL-AIPRYIKPFYDGEVCK 3196 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVL 726 L +D G+YTC A + G A + A L Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL 3227 Score = 50.0 bits (114), Expect = 5e-05 Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-TETNNFGFVALDIMSC 1642 LKN+++ EG A F R+ + KVEW+ K +KS +RF ++ L I Sbjct: 3242 LKNIKVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYTLTISDV 3299 Query: 1643 LPEDSGTYTCRAINALGEAVTSG 1665 ED GTY C A N G+ SG Sbjct: 3300 AMEDFGTYKCVASNDAGKVQCSG 3322 Score = 49.6 bits (113), Expect = 6e-05 Identities = 40/150 (26%), Positives = 68/150 (45%), Gaps = 12/150 (8%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 G RP L L ++ +KE + A C + P+ +W+ + ++R R ++ G Sbjct: 6 GDRPQILQPLEGVD-VKEDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSEVVNG 62 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225 L I T AED G Y C N+ G A + L N+ + + P+ K++ ++A Sbjct: 63 MATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPL------NVRVPVK-PSFTSKMKPVDA 115 Query: 2226 -QGHSTRIEVEEPKISPPRFVTELRGTTHV 2254 +G R +V K SP V +G+T + Sbjct: 116 EEGQEVRFDV-HVKGSPKPDVVWYKGSTMI 144 Score = 49.6 bits (113), Expect = 6e-05 Identities = 57/213 (26%), Positives = 84/213 (39%), Gaps = 40/213 (18%) Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250 EG+ L C++ G P +EW VT R +T ++ L I D G Y Sbjct: 312 EGEESKLVCKVT--GKPAPTIEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTY 369 Query: 1251 TVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA 1310 V A N D+ +I ++Q+ E R TK Sbjct: 370 KVVARN---------------------DSGTAHSIAELQVQE---RSTK----------- 394 Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV-A 1369 P+ +L ++ + G V + R+ G +VEW I+ G RF A E D V + Sbjct: 395 PEIEDSLRDVSALPGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEVFS 452 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + + D+G Y C ATN+ GEA + L V Sbjct: 453 LIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485 Score = 49.6 bits (113), Expect = 6e-05 Identities = 61/252 (24%), Positives = 94/252 (37%), Gaps = 14/252 (5%) Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRT 3099 ++ G P F K + I EG+ +E L + +EWF + I R I Sbjct: 1464 NEVGSRPIFQQKLKAVSTI-EGESTRFEVKL--SAMPRPTVEWFKSSSQIYDGGRFTITE 1520 Query: 3100 VYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159 G+ VL I T D+GTY A N G+ L + P F + E Sbjct: 1521 EENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLT--VPEF---MDKAE 1575 Query: 3160 G-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218 G ++ + E TV P ++EW+ + + S+RI S + ++ D Sbjct: 1576 GPIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDD 1635 Query: 3219 SGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPS 3278 SG Y C A NK G ++ K + PD + + E +G T S Sbjct: 1636 SGMYQCVARNKAGSSSRTFNLDVQKKKVI---GNAPDIITHLISKEVKEGGTVTLECTVS 1692 Query: 3279 AEPPKFITQIQD 3290 +P I +D Sbjct: 1693 GKPAPNIEWYKD 1704 Score = 49.6 bits (113), Expect = 6e-05 Identities = 34/99 (34%), Positives = 47/99 (47%), Gaps = 5/99 (5%) Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--F 1232 S+P+F Q L + EG++ E +L M PT VEWF + + G RF + Sbjct: 1468 SRPIFQQKLKAVSTI-EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENS 1524 Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271 G L I D G Y V A N+LG + A++RV E Sbjct: 1525 GVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNE 1563 Score = 49.6 bits (113), Expect = 6e-05 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 2/93 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P I L S EGG + E + G P IEW K+G A+ R + F S+ Sbjct: 1668 PDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASV 1725 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729 D GEY C A + G A++ A L VT Sbjct: 1726 TFTDAQGFDDGEYKCVATNPLGSAQSSARLTVT 1758 Score = 49.6 bits (113), Expect = 6e-05 Identities = 36/116 (31%), Positives = 58/116 (50%), Gaps = 10/116 (8%) Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964 + E P++I + +LV+G L +E + P +IEWY N +++ SR +L+ Sbjct: 2151 EEELTIPQFIGDVPGVVELVQGDNYDLS--LEVRGTPRPEIEWYHNERLIYATSRVQLSF 2208 Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTE 3020 T+ L +V DSG+Y CKA N G T S + N+ + + P+GTE Sbjct: 2209 ISSKATIALYNVTLDDSGLYRCKAVNTAG---TGSKQF-----NINVQPKRPEGTE 2256 Score = 49.6 bits (113), Expect = 6e-05 Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 10/150 (6%) Query: 993 ATTSANLTIVTKKDIIA---ESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ----KPRF 1045 AT+ L+ ++ K IA + GL + + + A SK+ V+ + +P Sbjct: 2200 ATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNI 2259 Query: 1046 LGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDI 1105 + LK ++ EG+ A E V T T+EWY +G ++ + R+++ + G L I Sbjct: 2260 VSGLKSV-EVKEGEQAELEFVVSGTP--TPTLEWYRDGLRVKESRRVRSTLENGIARLVI 2316 Query: 1106 ASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 AED G Y RN G SA + + Sbjct: 2317 TETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346 Score = 49.6 bits (113), Expect = 6e-05 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 11/128 (8%) Query: 1417 GLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL 1476 G K Q D R + ++ V +P F + +E V EG FE +++ Sbjct: 2325 GTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVE-VTEGDRAKFEVRVKGYPYP-- 2381 Query: 1477 KVEWFKNGQPVTIGHRFR--PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 +VEW+ + RF + + GY +L + +++ ED+G+Y C AVN G + Sbjct: 2382 EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAG------KS 2435 Query: 1535 TCRSTTDI 1542 TCR+ ++ Sbjct: 2436 TCRADLEV 2443 Score = 49.6 bits (113), Expect = 6e-05 Identities = 28/88 (31%), Positives = 37/88 (42%), Gaps = 2/88 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F L + +G FEC V +P +I W + K L K +D L Sbjct: 3142 FFRQLRRVEAVQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYIKPFYDGEVCKLTF 3199 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 T ED G YTC A+N G A++ SL Sbjct: 3200 YETQPEDEGDYTCVASNEAGEASSHASL 3227 Score = 49.6 bits (113), Expect = 6e-05 Identities = 32/92 (34%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Query: 1584 LKNVEIKEGQRAHFERRLIPVSDA-TLKVEWYHNNKPLKSGSRFT--ETNNFGFVALDIM 1640 ++++++ EG RA F + VS KVEW ++ L++G R + E L I Sbjct: 3533 IQDLDVIEGDRAKFH---VEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTIT 3589 Query: 1641 SCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672 +C P DSG YTC A N GE G V K Sbjct: 3590 NCKPTDSGKYTCIARNKAGENTCHGRLAVKEK 3621 Score = 49.6 bits (113), Expect = 6e-05 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323 +P K+ Q G +SGNP P TWF+ + L + + I TT + ++L Sbjct: 5964 APAKVDQAATPGSGVVGGKITLTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSL 6023 Query: 324 RVRNTQKSDSGHYTLLAENPNG---CIV 348 + Q D G Y L+ +N G C+V Sbjct: 6024 TIERIQFRDEGEYELVVKNDGGEDSCVV 6051 Score = 49.2 bits (112), Expect = 8e-05 Identities = 66/262 (25%), Positives = 100/262 (38%), Gaps = 34/262 (12%) Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY- 2158 + E + G PV L + + G+ A F RV +DWF + + R+ Sbjct: 974 VNEVEKGVGPVIEEKLKDV-TVMPGEEAEFSIRVSG----RAEVDWFKDEVMLNDEGRFI 1028 Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLE 2218 D G +L I ED GTY C N+ G+ L + + I+ + + E Sbjct: 1029 MEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI---KEAIVAPEEVDAAE 1085 Query: 2219 KIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEF 2278 + IE PKI+ P E+ EG+ EC V P+ +E+ Sbjct: 1086 TVP----------IEGSAPKITKPLESVEVN------EGEDFDLECVVSG--SPSPTVEW 1127 Query: 2279 YHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKG 2338 + L+++ R D L + PED GEY IN G S T K Sbjct: 1128 TKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKA----STTGEVKV 1183 Query: 2339 SIISESQRPEGLEKIRELESAE 2360 +++S RPE K+ +E E Sbjct: 1184 NVLS---RPEFKIKMSPVEVTE 1202 Score = 49.2 bits (112), Expect = 8e-05 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--IT 959 V E +P F+ +K +S EG FE +L + T VEW K + R IT Sbjct: 1463 VNEVGSRPIFQQKLK-AVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTIT 1519 Query: 960 TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 N G L I+ + DAG Y AYN +G+ T+ A L + Sbjct: 1520 EEENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV 1561 Score = 49.2 bits (112), Expect = 8e-05 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 3/125 (2%) Query: 3828 TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887 T P+FI + VE +G ++ +E + P+ IEWY N +L+ + R + + Sbjct: 2155 TIPQFIGDVPG-VVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKA 2213 Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK-KLPDIILQNQVPRGMKRSEALTQM 3946 ++ + V +DSG Y C+AVN G + I+ + K P+ N + G+K E Sbjct: 2214 TIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPN-IVSGLKSVEVKEGE 2272 Query: 3947 EATIK 3951 +A ++ Sbjct: 2273 QAELE 2277 Score = 49.2 bits (112), Expect = 8e-05 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 2/91 (2%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP+ + L E EG++ L CR+ G T +EW+ + P+K R + D Sbjct: 2846 APEIVQRLKACEVPEGSSFKLRCRV--TGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400 L+ L D G Y A N LG TS L Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAEL 2934 Score = 49.2 bits (112), Expect = 8e-05 Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%) Query: 2102 EEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTT 2161 ++ G P F L +E + +G A FEC+V +P + W +G+++ + Sbjct: 3133 KKSKGIIPEFFRQLRRVEAV-QGSTARFECKVSGHPEPQIA--WLKDGKELAIPRYIKPF 3189 Query: 2162 HDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIR 2221 +D L T ED G Y C A+N+ GEA + +L ++ + + ++ + Sbjct: 3190 YDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASLVLSKPLVMPEFKERLKNIKVVE 3249 Query: 2222 QLEAQGHSTRIEVE-EPKI 2239 EAQ S R++ E EPK+ Sbjct: 3250 GDEAQ-FSVRVKGEPEPKV 3267 Score = 49.2 bits (112), Expect = 8e-05 Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 3/93 (3%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P F L+ + V+G +A FE +V + + W +GK++ I+ ++D Sbjct: 3140 PEFFRQLRRV-EAVQGSTARFECKVSGHPE--PQIAWLKDGKELAIPRYIKPFYDGEVCK 3196 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 L + ED G YT VA N AGEA AS+ + Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASLVL 3229 Score = 49.2 bits (112), Expect = 8e-05 Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 4/97 (4%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYV 1768 P F P++D+ V E A F + G P +VEWL+ + R++ D Sbjct: 3527 PHFDHPIQDLDVIEGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSLEEDRETQMY 3584 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 L + P DSG YTC A N+ GE L V+ K Sbjct: 3585 FLTITNCKPTDSGKYTCIARNKAGENTCHGRLAVKEK 3621 Score = 48.8 bits (111), Expect = 1e-04 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 4/137 (2%) Query: 1689 NQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748 N+ + + + +E+I P F + V E ++ AR+ G P +EW + Sbjct: 472 NEAGEAESMAQLTVNEELI--GPRFEKMKESFTVVEGESVELVARV--TGKPAPEIEWTK 527 Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 +G + +N + T L ++ + +DSG Y C A N+ G A + L VQ K Sbjct: 528 DGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPK 587 Query: 1809 QLESQHESALQKIQQLE 1825 + S L+ ++ E Sbjct: 588 GTAPEIVSELRPVEATE 604 Score = 48.8 bits (111), Expect = 1e-04 Identities = 51/168 (30%), Positives = 76/168 (45%), Gaps = 17/168 (10%) Query: 1131 ASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQP--LSNPPP 1188 A +T+E S D+ GLY T +S + +Q++ + KP P +S P Sbjct: 547 AVLTIEESSRDDS-----GLYRCTAR-NKSGTADMTFQLD-VQPKKPKGTAPEIVSELRP 599 Query: 1189 V--SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSAD 1246 V +EG + L C + G P +EW NG V R K G V L I + D Sbjct: 600 VEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADD 657 Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVI--ERSDIVTDTQNEQAI--EQIQL 1290 G+YT N LGSA + ++VI R + T + +A+ E++QL Sbjct: 658 QGDYTCIVRNELGSAESKTKLKVIAFARPEFRTKLKPVKAVEGEEVQL 705 Score = 48.8 bits (111), Expect = 1e-04 Identities = 61/233 (26%), Positives = 93/233 (39%), Gaps = 30/233 (12%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTFFNFGYV 967 P + +KD +++ G A F R+ V+W KD + R I + G Sbjct: 983 PVIEEKLKD-VTVMPGEEAEFSIRVS----GRAEVDWFKDEVMLNDEGRFIMEGGDNGRF 1037 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027 +LTI V D G Y C +N G+ TT A L I K+ I+A + DA+ Sbjct: 1038 SLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI--KEAIVAPEE-----------VDAA 1084 Query: 1028 RYSKRTEEEVKIT-QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086 E V I P+ PL+ ++ EG+ E V + TVEW + ++ Sbjct: 1085 -------ETVPIEGSAPKITKPLESV-EVNEGEDFDLECVV--SGSPSPTVEWTKDLVKL 1134 Query: 1087 TSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139 ++ R++ D L R ED G Y N G+A + + V S Sbjct: 1135 RTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLS 1187 Score = 48.8 bits (111), Expect = 1e-04 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 6/92 (6%) Query: 66 PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125 P E S P + ++ +G + E + G+P+P V WT+ L + S R E+ Sbjct: 1088 PIEGSAPKITKPLESVEVNEGEDFDLECVVSGSPSPTVEWTKDLVKL----RTSYRLKEK 1143 Query: 126 -TGDVS-LLIKQIGPGDEGEYTCTARNQYGEA 155 G+V+ L+ KQ P D GEY CT N++G+A Sbjct: 1144 LDGNVAKLVFKQARPEDIGEYKCTVINEHGKA 1175 Score = 48.8 bits (111), Expect = 1e-04 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 3/116 (2%) Query: 750 LEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKD 809 + ++ K ++ RP+F + + E+ EG A FE ++ P ++VEW+K Sbjct: 1169 INEHGKASTTGEVKVNVLSRPEFKIKMSPV-EVTEGSEAAFEVRVEGF--PKLQVEWFKG 1225 Query: 810 GRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 I S R T + ++ I ++ EDAG Y A N G+ S A + V R Sbjct: 1226 MTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKER 1281 Score = 48.8 bits (111), Expect = 1e-04 Identities = 60/218 (27%), Positives = 84/218 (38%), Gaps = 38/218 (17%) Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLC 3495 E ++T +P +V WY +GK R L+I+ EDSG Y C Sbjct: 2465 EGGETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKC 2524 Query: 3496 RAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESG 3555 A N G A + +++V E P G E TI + L+ VDT+ EA Sbjct: 2525 EARNKLGFADKSFTIRV--------EVPKPTGEEPTI--LQRLQ----PVDTIEGEA--- 2567 Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615 ECR+ + + + W +G LT +R+KT D Sbjct: 2568 -------------------IKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVC 2606 Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653 L I V D G+Y C A N G A S +L V R+ Sbjct: 2607 TLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLERE 2644 Score = 48.8 bits (111), Expect = 1e-04 Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 6/129 (4%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 +E ++ K P F +LR V +G TA FEC+V +P +I + +GK L Sbjct: 3130 VEAKKSKGIIPEFFRQLRRVEAV-QGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYI 3186 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 +D L PED G+Y+ A N G +S S+ V +K ++ E + E L+ Sbjct: 3187 KPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVMPEFK--ERLK 3243 Query: 2352 KIRELESAE 2360 I+ +E E Sbjct: 3244 NIKVVEGDE 3252 Score = 48.4 bits (110), Expect = 1e-04 Identities = 41/153 (26%), Positives = 67/153 (43%), Gaps = 4/153 (2%) Query: 3362 KLGRDSTKANLKCTSKENLI-LDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAP 3420 KL DS K +++ + + N + + S P + + R D V+ KG AP Sbjct: 240 KLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFDVKVKAPKGDAP 299 Query: 3421 VFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVIL 3480 FT+ L+++ + EGE + ++T P +EW + R RT + L Sbjct: 300 SFTIDLTHVRAI-EGEESKLVCKVTGKPAP--TIEWLKGELPVTTSLRVRTDFEKNVATL 356 Query: 3481 EISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 I T D+G Y A N+ G A + A ++VQ Sbjct: 357 VIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQ 389 Score = 48.4 bits (110), Expect = 1e-04 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 2/98 (2%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 + V+ P+F + +E EG+ E R++ G ++VEWF I+ R+ + Sbjct: 1183 VNVLSRPEFKIKMSPVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTAD 1240 Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 + + + +V ED+G Y C ATN G+ + L V Sbjct: 1241 KNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278 Score = 48.4 bits (110), Expect = 1e-04 Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 32/161 (19%) Query: 2576 NDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVD 2635 +DAG+Y C+A N AG SWE +++K++A P+ Sbjct: 1337 SDAGVYKCQATNAAGSAS--------------------RSWE-VKVKQSA----PKT--- 1368 Query: 2636 TGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF 2695 TG + PI L++ + + EG L +V P I+W ++GV + +R+K F Sbjct: 1369 TG--EEPIIIRKLQAQE-IDEGSTANLVCKVTA-AKPEPSIKWTRDGVKIRENSRIKMVF 1424 Query: 2696 DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 D +L+I DD G+Y TN G A ST + + + Sbjct: 1425 DGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNE 1465 Score = 48.4 bits (110), Expect = 1e-04 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 5/108 (4%) Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG--HRF 1359 R +TV P+F + L +E VEG+ + R++ VEW+ I H+ Sbjct: 1754 RLTVTVPSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQI 1811 Query: 1360 RPAYEFDYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406 YE D +L +L+ ED+ +Y C A N+ G+ L VI K+ Sbjct: 1812 TEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEKQ 1859 Score = 48.4 bits (110), Expect = 1e-04 Identities = 41/137 (29%), Positives = 61/137 (44%), Gaps = 13/137 (9%) Query: 1567 TDMVDEVTTQA---PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN-NKPLKS 1622 T V + TQ PI +KNVE + G+ FE I V + +H ++ + Sbjct: 2046 TTTVQVIVTQRSIRPIFGQKMKNVEGRIGEDVRFE---IQVEGTPVPAVTFHRESEQIYD 2102 Query: 1623 GSRFT--ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQ 1680 G R++ E N G L I + PED+G Y C A+N GE + G V + +I Q Sbjct: 2103 GGRYSIVEEEN-GLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI---PQ 2158 Query: 1681 HEGALPRLNQLEDTSKY 1697 G +P + +L Y Sbjct: 2159 FIGDVPGVVELVQGDNY 2175 Score = 48.4 bits (110), Expect = 1e-04 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 4/100 (4%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GFV 3478 P+F + N+E R GE+ FE ++ T P V ++ + + G R+ + G Sbjct: 2060 PIFGQKMKNVEG-RIGEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLF 2116 Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518 +L I T PED+GEY C A N GE + + V+ + I Sbjct: 2117 VLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI 2156 Score = 48.4 bits (110), Expect = 1e-04 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 3/101 (2%) Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 +EE+ + PQFI + + EL +G N ++ L P +EWY + R I A+SR+ Sbjct: 2150 VEEELTI-PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQL 2206 Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 F ++ + ++ +D+G Y +AVN G +I V Sbjct: 2207 SFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV 2247 Score = 48.4 bits (110), Expect = 1e-04 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR--TFHD 3336 A P+F ++ V ++ EG A FE R+ P+ VEW++ ++ R+ + + Sbjct: 2349 ATRPEFKEKLTKV-EVTEGDRAKFEVRVKGYPYPE--VEWYHGSNRILDEDRFEIESVKE 2405 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 G L + +E++G Y+C+A NK G+ + +A+L+ ++ Sbjct: 2406 TGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQ 2447 Score = 48.4 bits (110), Expect = 1e-04 Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 3/104 (2%) Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 + + T + P ++ LQ + + EG E +++ +PT + W KDG +RI + Sbjct: 2543 VPKPTGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKT 2599 Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 F+ +L I ++ D G Y A N G A S+A + V R Sbjct: 2600 YFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLER 2643 Score = 48.4 bits (110), Expect = 1e-04 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 8/106 (7%) Query: 626 PPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF 685 P GEE P + L+ V +EG I E R+ +PT I WLK+G +R Sbjct: 2546 PTGEE------PTILQRLQPVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRI 2597 Query: 686 TSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 + F +L + + + D G Y C A +++G A + A L V R Sbjct: 2598 KTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLER 2643 Score = 48.4 bits (110), Expect = 1e-04 Identities = 40/146 (27%), Positives = 68/146 (46%), Gaps = 8/146 (5%) Query: 635 PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694 P P FI PL +EG I E R+ P +EW K+G++ + + F + Sbjct: 3429 PAPLFIAPLHDQEVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYTEFDGQHC 3486 Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE-DY 753 +L + I+D G Y C A + G + A L V A I HP +Q + +E D Sbjct: 3487 TLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV-KEALIIPHFDHP--IQDLDVIEGDR 3543 Query: 754 SKYQHQESIEEQTSQRPQFIRPLQDL 779 +K+ H E + + + + ++++ Q+L Sbjct: 3544 AKF-HVE-VSGKPAAKVEWLKGDQEL 3567 Score = 48.4 bits (110), Expect = 1e-04 Identities = 34/101 (33%), Positives = 48/101 (47%), Gaps = 5/101 (4%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP FI L+ ++ EG++ ECR+ P P VEW +G+ + + T D Sbjct: 3430 APLFIAPLHDQ-EVVEGETIRLECRVRATPRP--MVEWKKDGRTFKEDYHIYTEFDGQHC 3486 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943 L I ED G Y C A N G+ S +L V KE++I Sbjct: 3487 TLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV--KEALI 3525 Score = 48.4 bits (110), Expect = 1e-04 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 3/94 (3%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P F+ PL ++VEG++ E RV ++ VEW +G+ I T D + Sbjct: 3431 PLFIAPLHD-QEVVEGETIRLECRV--RATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCT 3487 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 L I + ED G Y +A+N G + A +TV+ Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK 3521 Score = 48.0 bits (109), Expect = 2e-04 Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 3/104 (2%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E P F+ +K+ ++ EG AR+ G +EW KDG+ V ++ + T Sbjct: 485 VNEELIGPRFEK-MKESFTVVEGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTK 541 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005 LTI+ + D+G Y C A N G A + L + KK Sbjct: 542 ERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKK 585 Score = 48.0 bits (109), Expect = 2e-04 Identities = 24/84 (28%), Positives = 51/84 (60%), Gaps = 6/84 (7%) Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSINSLRNDD 2711 + EG V ++ +V + +PN ++WFK+G + +T +K + + + ++SL +D Sbjct: 797 VTEGNEVSIQLRV--KANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSL--ED 852 Query: 2712 SGIYTCKATNLLGEAVSTASIKIE 2735 +G+Y C+A+N LG+A + +K++ Sbjct: 853 TGVYKCEASNRLGKASRSFDVKVQ 876 Score = 48.0 bits (109), Expect = 2e-04 Identities = 56/319 (17%), Positives = 121/319 (37%), Gaps = 13/319 (4%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 S P F+ +G A FE ++ G P V W + + + +Y+ + Sbjct: 1187 SRPEFKIKMSPVEVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYT--FTADKNRY 1244 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVEH 188 +++I + D G Y C A N G+ + E V++ VE Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTIDSEVNKEVEI 1304 Query: 189 KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES 248 K T G S T A + D Y+ + + S ++ + Sbjct: 1305 KV--TTGEPIRDSINTDVRAIGDSHTCFIVRAKLSDAGVYKC-QATNAAGSASRSW---- 1357 Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG-NPRPRVTWFKNGQRLI 307 +V++ ++ G P I +K + ++ EG+ A +++ P P + W ++G ++ Sbjct: 1358 EVKVKQSAPKTTG--EEPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKIR 1415 Query: 308 NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367 +++ +++ +L +R+ D G Y + N G ++ + V + Q+ Sbjct: 1416 ENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQK 1475 Query: 368 SQYITDTQQRETEERIEIS 386 + ++ + T +++S Sbjct: 1476 LKAVSTIEGESTRFEVKLS 1494 Score = 48.0 bits (109), Expect = 2e-04 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 5/115 (4%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYV 1768 P+F +K + E ++ FE +L + P+ VEW ++ I R T + G Sbjct: 1470 PIFQQKLKAVSTIEGESTRFEVKLSAM--PRPTVEWFKSSSQIYDGGRFTITEEENSGVY 1527 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL-QLESQHESALQKIQ 1822 L ++ N ED+GTY A N LG+ + + L V ++ + + E ++K + Sbjct: 1528 VLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEKTE 1582 Score = 48.0 bits (109), Expect = 2e-04 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%) Query: 69 PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128 PS P F+Q + +G AKF+ +++ P P V W R + + ++ + + D Sbjct: 1760 PSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQITEPYEGDD 1819 Query: 129 V-SLLIKQIGPGDEGEYTCTARNQYGEAIC 157 SL+I D Y C A N+ G+ C Sbjct: 1820 TYSLIILNTTMEDAAMYKCVAFNEAGKTTC 1849 Score = 48.0 bits (109), Expect = 2e-04 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 4/102 (3%) Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMH 1763 ++ P F + + V E A FE R+ G P VEW I +R + ++ Sbjct: 2347 IVATRPEFKEKLTKVEVTEGDRAKFEVRV--KGYPYPEVEWYHGSNRILDEDRFEIESVK 2404 Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + GY +L + V ED+G Y C A+N+ G++ + L V + Sbjct: 2405 ETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446 Score = 48.0 bits (109), Expect = 2e-04 Identities = 39/179 (21%), Positives = 70/179 (39%), Gaps = 9/179 (5%) Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLR 2541 E K+ ++ R E P E+P Q L P + EG+ E RV G P Sbjct: 2525 EARNKLGFADKSFTIRVEVPKPTGEEPTILQRLQ-PVDTIEGEAIKMECRVS--GKPEPT 2581 Query: 2542 FEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXX 2601 W +G+ +R +T D TL I V D G+Y C A N +G Sbjct: 2582 ITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSG------SAHSS 2635 Query: 2602 XXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHV 2660 ++++ RP E++Q ++++ + + P+ + + + +G ++ Sbjct: 2636 AELTVLEREARPRILEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYI 2694 Score = 48.0 bits (109), Expect = 2e-04 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 6/130 (4%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P F +++ ++ +G F+C+V G P +I W +G+ A + D Sbjct: 3140 PEFFRQLR-RVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCK 3196 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814 L D G+YTC A+N+ G A++ A + S + +V+ + + + K+ E + Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASLVLS--KPLVM-PEFKERLKNIKVVEGDEA 3253 Query: 3815 RISDAPKEEP 3824 + S K EP Sbjct: 3254 QFSVRVKGEP 3263 Score = 48.0 bits (109), Expect = 2e-04 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC-DFGFV 3478 P F L NI+ + EG+ A F R+ +P KVEW+ GK +K+ +RF + + Sbjct: 3236 PEFKERLKNIKVV-EGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 L IS ED G Y C A N+ G+ + + V+ Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVK 3327 Score = 48.0 bits (109), Expect = 2e-04 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 5/101 (4%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P FI + D ++VEG++ E R+ P VEW +G+ + T D Sbjct: 3431 PLFIAPLHD-QEVVEGETIRLECRVRATPRP--MVEWKKDGRTFKEDYHIYTEFDGQHCT 3487 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLIL 3382 L I E+ G YEC+A NK GR + A L T KE LI+ Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRGRSVAQL--TVKEALII 3526 Score = 47.6 bits (108), Expect = 2e-04 Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 7/111 (6%) Query: 3404 MVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL 3463 M + D ++ KG AP L +E EG++A ++ P +EW NG + Sbjct: 575 MTFQLDVQPKKPKGTAPEIVSELRPVE-ATEGDDAVLSCTISGKPVPT--IEWLKNGIRV 631 Query: 3464 KAGSRFRTFCDF--GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 K SR RT CD G V L I T +D G+Y C N G A + +KV Sbjct: 632 K-DSR-RTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680 Score = 47.6 bits (108), Expect = 2e-04 Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 7/142 (4%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E PEF+ + I + EG + R++ + V+W KDGRP+ S++ Sbjct: 778 VKEREFAPEFEGDEEGPIVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTKRDIK 835 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021 L I ++ D G Y C A N +G+A+ S ++ + K + + P L K++ Sbjct: 836 RRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQVKG---PKGEAPIILSKLR 892 Query: 1022 YLEDASRYSKRTEEEVKITQKP 1043 +E + + T+ + T KP Sbjct: 893 PVE--TEEGEETKLKCTFTGKP 912 Score = 47.6 bits (108), Expect = 2e-04 Identities = 56/230 (24%), Positives = 86/230 (37%), Gaps = 37/230 (16%) Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749 E+ P F + + I V EG V RV+ +P +DWF +GRP ++ Sbjct: 780 EREFAPEFEGDEEGPIVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTKRDIKRR 837 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809 L I D G Y C A+N+ G A S D+ ++ + P+G Sbjct: 838 GEEHTLAIHVSSLEDTGVYKCEASNRLGKA--------SRSFDVKVQVKGPKG------- 882 Query: 3810 ELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869 E PI+ +++++ EE E + +C K P EW R+G Sbjct: 883 ------------EAPII------LSKLRPVETEEGEETKLKCTFTGKPAP--TCEWTRDG 922 Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 + S + +L I +D G Y C ND G T A + Sbjct: 923 IRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEV 972 Score = 47.6 bits (108), Expect = 2e-04 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG FE VE P L++EWF + RY T D + ++ I + ED+G Y Sbjct: 1202 EGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGY 1259 Query: 2847 TCKATNSKGSATTSGSL 2863 C ATN+ G T+ L Sbjct: 1260 RCVATNTAGKTTSRADL 1276 Score = 47.6 bits (108), Expect = 2e-04 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 2/87 (2%) Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431 T + P+ + LQ I EG TA+ C+ + P ++W R+ I ++SRI D Sbjct: 1369 TGEEPIIIRKLQ-AQEIDEGSTANLVCK-VTAAKPEPSIKWTRDGVKIRENSRIKMVFDG 1426 Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLG 2458 S+TI +DEGVY +N G Sbjct: 1427 ETCSLTIRDATLDDEGVYKVTLTNEYG 1453 Score = 47.6 bits (108), Expect = 2e-04 Identities = 24/76 (31%), Positives = 39/76 (51%) Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721 LE V R P ++EWFK TL +R+ T++++ L DDSG+Y C A N Sbjct: 1586 LELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARN 1645 Query: 2722 LLGEAVSTASIKIEDR 2737 G + T ++ ++ + Sbjct: 1646 KAGSSSRTFNLDVQKK 1661 Score = 47.6 bits (108), Expect = 2e-04 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 6/101 (5%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITT-FFNF 964 KPEFK ++ + + EG A F+ R++ VEW + + S R IT + Sbjct: 1762 KPEFKQKLRP-LEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITEPYEGD 1818 Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005 +L I + T+ DA Y C A+N G+ T A+LT++ K+ Sbjct: 1819 DTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEKQ 1859 Score = 47.6 bits (108), Expect = 2e-04 Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 3/125 (2%) Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTH--IQNIEGLKDGQSAHFECTVV 3174 DS TY A NK G A SV+L V +G KP +Q ++ + + + F+ Sbjct: 2811 DSATYKAVAKNKAGVARRSVEL-LVKPKRGLKPGEAAPEIVQRLKACEVPEGSSFKLRCR 2869 Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234 P IEWY + P++ + R+ L+ T+ D G Y+ A N G Sbjct: 2870 VTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVS 2929 Query: 3235 TRATI 3239 T A + Sbjct: 2930 TSAEL 2934 Score = 47.6 bits (108), Expect = 2e-04 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT-VYDMGFVS 3888 P+F ++K+ V E + +F RV+ + +PK +EW++ GK + S R+ + + + Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRVKGEPEPK--VEWFKTGKKIKSHARFSSKAGEKHTYT 3293 Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912 L I V ED G Y C A ND G+ Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGK 3317 Score = 47.6 bits (108), Expect = 2e-04 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 5/86 (5%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD--FGY 2433 P F P+Q++D I EG A F + G P KVEW + ++ + + R++ D Sbjct: 3527 PHFDHPIQDLDVI-EGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459 +TI++ + D G Y C A N GE Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGE 3609 Score = 47.6 bits (108), Expect = 2e-04 Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 7/110 (6%) Query: 58 RQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNK 117 RQPI PG P F Q ++ +G A+ +++G P P + W + + E + Sbjct: 3725 RQPIP---PGAVKPS-FLQRMQDLEIVEGSAARLCVRVQGVPEPEIDWYKDNRVIREGGR 3780 Query: 118 YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS--VYIQPEG 165 + E+ G L+I+ D G Y C N G+A CS ++I+ G Sbjct: 3781 VEFEF-EEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHG 3829 Score = 47.2 bits (107), Expect = 3e-04 Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 4/101 (3%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E + KPE + ++D +S G F+ R+ G +VEW K +E R T Sbjct: 388 VQERSTKPEIEDSLRD-VSALPGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIA 444 Query: 962 FNFGYV-ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 V +L I+ + DAG Y C A N G+A + A LT+ Sbjct: 445 EESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485 Score = 47.2 bits (107), Expect = 3e-04 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI---FRFGY 693 P+F LK V A+EG ++ + ++E G P IEW + I S RF + G Sbjct: 686 PEFRTKLKPVKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGL 743 Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 SL + L + D+G A +A+G A ++A L V R Sbjct: 744 YSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKER 781 Score = 47.2 bits (107), Expect = 3e-04 Identities = 42/158 (26%), Positives = 74/158 (46%), Gaps = 12/158 (7%) Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFT-TTPSDLILSENSSAHFECR 3580 S+L GTI +A T E PEF ++++E + + R Sbjct: 749 SKLQLDDTGTIKVVATNASGKATSRADLEVKEREFAPEFEGDEEGPIVVTEGNEVSIQLR 808 Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGSR--VKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638 + N ++ V+WF +G+P+ ++ +K + + + + + D G+Y C+A+NR Sbjct: 809 -VKANPNA-DVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSL--EDTGVYKCEASNRL 864 Query: 3639 GEATVS--CKLQVKGRQG---IILEPQLPSHFKSGTES 3671 G+A+ S K+QVKG +G IIL P + G E+ Sbjct: 865 GKASRSFDVKVQVKGPKGEAPIILSKLRPVETEEGEET 902 Score = 47.2 bits (107), Expect = 3e-04 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 5/78 (6%) Query: 2118 LENLK--EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV-ALDILYT 2174 L+N+K EGD A F RV+ +P ++WF G+KI++ R+ + + L I Sbjct: 3242 LKNIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYTLTISDV 3299 Query: 2175 YAEDSGTYMCKATNKLGE 2192 ED GTY C A+N G+ Sbjct: 3300 AMEDFGTYKCVASNDAGK 3317 Score = 47.2 bits (107), Expect = 3e-04 Identities = 38/135 (28%), Positives = 57/135 (42%), Gaps = 8/135 (5%) Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159 IE ++P P+F+ L E + EG+ ECRV P ++W +G+ + + Sbjct: 3424 IESKKPA--PLFIAPLHDQE-VVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIY 3478 Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEK 2219 T D + L I ED G Y C A NK G + L V II HP ++ Sbjct: 3479 TEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK-EALIIPHFDHP--IQD 3535 Query: 2220 IRQLEAQGHSTRIEV 2234 + +E +EV Sbjct: 3536 LDVIEGDRAKFHVEV 3550 Score = 46.8 bits (106), Expect = 4e-04 Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 46/231 (19%) Query: 2232 IEVEEPKISPPRFVTELRGTTHV--FEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA 2289 ++V+ PK P F +L THV EG+ + C+V P IE+ + ++ Sbjct: 289 VKVKAPKGDAPSFTIDL---THVRAIEGEESKLVCKVTGKPAPT--IEWLKGELPVTTSL 343 Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG 2349 R F+ +L I+ DAG Y V A N G S Sbjct: 344 RVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHS--------------------- 382 Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409 I EL+ E +PEI + + R V P G+ F R+ G P K Sbjct: 383 ---IAELQVQERSTKPEIEDSL---RDVSALP---------GERVKFKVRI--GGKPKPK 425 Query: 2410 VEWFRNEKLIEDSSRITKTHDFGYV-SMTISHVRDEDEGVYMCRASNLLGE 2459 VEW + + +IED R T + V S+ I + + D G Y C A+N GE Sbjct: 426 VEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGE 476 Score = 46.8 bits (106), Expect = 4e-04 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 4/100 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF--TSIFRFGYI 694 P F LK+V+ +EG FE ++ + PT +EW K+ I RF T G Sbjct: 1470 PIFQQKLKAVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVY 1527 Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734 L + NI+D+G Y A + G ++A+L V T+ Sbjct: 1528 VLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLTV 1567 Score = 46.8 bits (106), Expect = 4e-04 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 2/88 (2%) Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAE 1111 + ++ EG + E V + +EWY +G + T+ R+ T D ++ + Sbjct: 1676 SKEVKEGGTVTLECTVSGKP--APNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGF 1733 Query: 1112 DSGVYTVVARNAAGEAQLSASMTVETRS 1139 D G Y VA N G AQ SA +TV S Sbjct: 1734 DDGEYKCVATNPLGSAQSSARLTVTVPS 1761 Score = 46.8 bits (106), Expect = 4e-04 Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 6/106 (5%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897 V V P F +L P ++ EG A ++ RI+ YP P VEWY + R++ + Sbjct: 1757 VTVPSKPEFKQKLR-PLEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITE 1813 Query: 1898 DF---GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 + +L IL ED+ Y C A N G+ L V K+ Sbjct: 1814 PYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEKQ 1859 Score = 46.8 bits (106), Expect = 4e-04 Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 6/126 (4%) Query: 1301 VREDITVMQAPQFSRALHNI-ETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRF 1359 V E++T+ PQF + + E V+G N L ++ G +EW+ N + I R Sbjct: 2150 VEEELTI---PQFIGDVPGVVELVQGDNYDLSLEVR--GTPRPEIEWYHNERLIYATSRV 2204 Query: 1360 RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLE 1419 + ++ + L +V +DSG+Y C+A N G + V K+ E SGL+ Sbjct: 2205 QLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLK 2264 Query: 1420 KIQYLE 1425 ++ E Sbjct: 2265 SVEVKE 2270 Score = 46.8 bits (106), Expect = 4e-04 Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 2/77 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG+ I EC V +PT I W + + R K+ D +L I D GIY Sbjct: 2564 EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIY 2621 Query: 2847 TCKATNSKGSATTSGSL 2863 C A NS GSA +S L Sbjct: 2622 RCNAKNSSGSAHSSAEL 2638 Score = 46.8 bits (106), Expect = 4e-04 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 4/86 (4%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR-NEKLIEDSSRITKTHDFGY 2433 RP + LQ++D+ G+ A F R+ G P V+W+R +E++ I + GY Sbjct: 2646 RPRILEKLQDVDS-SVGERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGY 2702 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459 S+TI ++ EDEG Y N GE Sbjct: 2703 FSLTIEYIDYEDEGAYKAVVINDSGE 2728 Score = 46.4 bits (105), Expect = 6e-04 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101 +P+ L PL+G + + E ++A + T EWY + ++ + RI++ G Sbjct: 8 RPQILQPLEGVD-VKEDENAILSCTISGTP--TPNAEWYRDSIRVRESRRIKSEVVNGMA 64 Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 L I RAED G Y V RN G A A + V Sbjct: 65 TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 2/87 (2%) Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113 + +EG+ + +V + T+EW +T++ R++T + L I R D+ Sbjct: 309 RAIEGEESKLVCKVTGKP--APTIEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDA 366 Query: 1114 GVYTVVARNAAGEAQLSASMTVETRSS 1140 G Y VVARN +G A A + V+ RS+ Sbjct: 367 GTYKVVARNDSGTAHSIAELQVQERST 393 Score = 46.4 bits (105), Expect = 6e-04 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 2/95 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F +S T +EG + R+ G P +IEW K+G+++ ++ + R L Sbjct: 492 PRFEKMKESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVL 549 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 + + DSG Y C A + +G A+ L V P+ Sbjct: 550 TIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPK 584 Score = 46.4 bits (105), Expect = 6e-04 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 6/92 (6%) Query: 2648 LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSIN 2705 +K +VEG+ V L A+V + P +IEW K+G T+ T K D ++T+ + Sbjct: 497 MKESFTVVEGESVELVARVTGKPAP--EIEWTKDGKTVRKTNNVDTKERDDQAVLTIEES 554 Query: 2706 SLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 S DDSG+Y C A N G A T + ++ + Sbjct: 555 S--RDDSGLYRCTARNKSGTADMTFQLDVQPK 584 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 6/113 (5%) Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890 + + ++V P F T+L P K EG+ + ++E YP P+ +EWY ++ Sbjct: 673 ESKTKLKVIAFARPEFRTKLK-PVKAVEGEEVQLDVKVEGYPKPD--IEWYRGTTMIVES 729 Query: 1891 HRYRT---SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 R++ + G +L I + +D+G A N G+A S L V+ +E Sbjct: 730 GRFKVMEEEEEDGLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKERE 782 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 2/99 (2%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P F+ + GP + +EG R+ P P + EW+ + L R + Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVRGKPQPEL--EWFKYDRTLWKSSRINFKSRDNKFT 1625 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942 + + + +DSG Y C A N G + + L+VQ K+ I Sbjct: 1626 MTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664 Score = 46.4 bits (105), Expect = 6e-04 Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 2/81 (2%) Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841 ++EG + + A T P+ V WYKDGR + S + + L + + + EDAG Sbjct: 1875 VKEGDDLNISA--TIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932 Query: 842 SYTVRAVNKLGEAISTASIRV 862 SY A NKLG T +++V Sbjct: 1933 SYKCEANNKLGTVTKTYNVKV 1953 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 4/90 (4%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSL 2833 F L + EGD FE V+ P ++EW+ + + R++ S + Y SL Sbjct: 2354 FKEKLTKVEVTEGDRAKFEVRVKGYPYP--EVEWYHGSNRILDEDRFEIESVKETGYYSL 2411 Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 + +ED+G+Y C A N G +T L Sbjct: 2412 TVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441 Score = 46.4 bits (105), Expect = 6e-04 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 2/98 (2%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP +K V E + F+ R G P +EW ++ +P++ + R+ H Sbjct: 2846 APEIVQRLKACEVPEGSS--FKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807 LN D G Y A N LG TS+ L ++ S Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVS 2941 Score = 46.4 bits (105), Expect = 6e-04 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 8/83 (9%) Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV---HTLNDFGFIALDIDYIYA 3762 +VPEG CRV G PT I+W+ + P RV HT + + L+ + A Sbjct: 2857 EVPEGSSFKLRCRV--TGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETE---A 2911 Query: 3763 RDAGEYTCRATNKWGSATTTAKI 3785 RD G Y A N GS +T+A++ Sbjct: 2912 RDEGRYMLVAKNHLGSVSTSAEL 2934 Score = 46.4 bits (105), Expect = 6e-04 Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%) Query: 1438 ESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH 1497 +S I P F + + +E ++G FECK+ + ++ W K+G+ + I +P + Sbjct: 3134 KSKGIIPEFFRQLRRVE-AVQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYIKPFY 3190 Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557 D L + ED G YTC A N G E S + + +V E L+ I+V Sbjct: 3191 DGEVCKLTFYETQPEDEGDYTCVASNEAG--EASSHASLVLSKPLVMPEFKER-LKNIKV 3247 Query: 1558 LE 1559 +E Sbjct: 3248 VE 3249 Score = 46.4 bits (105), Expect = 6e-04 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 7/139 (5%) Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487 S K ++ ES P F+ P + V+EG+ + EC++ VEW K+G+ Sbjct: 3415 SASKSFTVVIESKKPAPLFIA-PLHDQEVVEGETIRLECRVRATPRP--MVEWKKDGRTF 3471 Query: 1488 TIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547 + D + L I ED G Y C A N G +LT + I Sbjct: 3472 KEDYHIYTEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKEALII---PH 3528 Query: 1548 NEAGLEQIQVLE-DRSKYH 1565 + ++ + V+E DR+K+H Sbjct: 3529 FDHPIQDLDVIEGDRAKFH 3547 Score = 46.4 bits (105), Expect = 6e-04 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP+F P+ D V E + E R+ P+ VEW ++G + + T D + Sbjct: 3430 APLFIAPLHDQEVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYTEFDGQHCT 3487 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 L +K ED G Y C A N+ G + + L V+ Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK 3521 Score = 46.0 bits (104), Expect = 8e-04 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 2/96 (2%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P+F + + VEG +V L R+ G +EW +GK ++ + D L Sbjct: 492 PRFEKMKESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVL 549 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406 + +DSG+Y C A N+ G A + L V KK Sbjct: 550 TIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKK 585 Score = 46.0 bits (104), Expect = 8e-04 Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 10/110 (9%) Query: 1302 REDITVMQ---APQFSRALHN-IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KT 1355 R D+ V + AP+F I EG V ++ R++ + V+WF +G+PI T Sbjct: 773 RADLEVKEREFAPEFEGDEEGPIVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYEST 830 Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 + E +A+ + S+ ED+GVY C+A+N+LG+A S ++V K Sbjct: 831 KRDIKRRGEEHTLAIHVSSL--EDTGVYKCEASNRLGKASRSFDVKVQVK 878 Score = 46.0 bits (104), Expect = 8e-04 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 2/102 (1%) Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360 V++ + AP L + E EG V LEC + G +EW+ +G R Sbjct: 1658 VQKKKVIGNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVM 1715 Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 ++ ++ D G Y C ATN LG A +S L V Sbjct: 1716 TTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757 Score = 46.0 bits (104), Expect = 8e-04 Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 6/102 (5%) Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-- 1094 V + KP F L+ ++VEG A F+ R++ S VEWY +IT + R Q Sbjct: 1757 VTVPSKPEFKQKLRPL-EVVEGSEAKFDVRIK--SYPKPEVEWYRGTTKITDSLRHQITE 1813 Query: 1095 -YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 Y +L I + ED+ +Y VA N AG+ A +TV Sbjct: 1814 PYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTV 1855 Score = 46.0 bits (104), Expect = 8e-04 Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%) Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048 V EG +++ AT+ P+ V WY +GR V + +T L + A ED G Sbjct: 1875 VKEGDDLNISATIA--GKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932 Query: 2049 TYMCKATNAVGEAVTTSSVKV 2069 +Y C+A N +G T +VKV Sbjct: 1933 SYKCEANNKLGTVTKTYNVKV 1953 Score = 46.0 bits (104), Expect = 8e-04 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 2/89 (2%) Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561 + E P F + G EL +G + Y+ + G P EWY N + SR + + Sbjct: 2151 EEELTIPQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSF 2208 Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590 T+ + +V +D+GLY CKA+N AG Sbjct: 2209 ISSKATIALYNVTLDDSGLYRCKAVNTAG 2237 Score = 46.0 bits (104), Expect = 8e-04 Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 18/160 (11%) Query: 2206 NIILDTQHPNGLEKIRQLEAQGHSTR-----IEVEEPKISPPRFVTELRGTTHVFEGKTA 2260 N+ LD +GL + + + G ++ ++ + P+ + P V+ L+ + V EG+ A Sbjct: 2219 NVTLDD---SGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLK-SVEVKEGEQA 2274 Query: 2261 HFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAI 2320 E V P L E+Y +G ++ + R T + G L I ED G Y + Sbjct: 2275 ELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQVR 2332 Query: 2321 NALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360 N LG +++ + + + RPE EK+ ++E E Sbjct: 2333 NDLGRTSTSAHLNIIV-------ATRPEFKEKLTKVEVTE 2365 Score = 46.0 bits (104), Expect = 8e-04 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P + LKSV EG + E + G PT +EW ++G ++ S R S G L Sbjct: 2257 PNIVSGLKSVEVKEGEQAELEFVVS--GTPTPTLEWYRDGLRVKESRRVRSTLENGIARL 2314 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + +D G Y C+ + G T A L++ Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346 Score = 46.0 bits (104), Expect = 8e-04 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 5/99 (5%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR--TFCDFGF 3477 P F L+ +E + EG+ A FE R+ P +VEWY + RF + + G+ Sbjct: 2352 PEFKEKLTKVE-VTEGDRAKFEVRVKGYPYP--EVEWYHGSNRILDEDRFEIESVKETGY 2408 Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516 L + ED+G Y C A N G++ A ++V ++ Sbjct: 2409 YSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQ 2447 Score = 46.0 bits (104), Expect = 8e-04 Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 4/100 (4%) Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233 ++ P VQ L V EG + L CR+ G PT +EW+ + + R + Sbjct: 2844 EAAPEIVQRLK-ACEVPEGSSFKLRCRVT--GTPTPTIEWYKSNMPLKPNGRVIIGHTGD 2900 Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273 L+ + + D G Y + A NHLGS TSA + +IE S Sbjct: 2901 QYFLNFLETEARDEGRYMLVAKNHLGSVSTSAEL-IIEPS 2939 Score = 46.0 bits (104), Expect = 8e-04 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 3/91 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P F L+ + V+G E +V +P +I W K+G L +K +D + Sbjct: 3140 PEFFRQLRRVEA-VQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYIKPFYDGEVCK 3196 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732 L+ + +D G YTC A+N GEA S AS+ Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL 3227 Score = 46.0 bits (104), Expect = 8e-04 Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 4/94 (4%) Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF-RPIHDFG 1500 + P F R K+I+ V+EG F +++ + KVEWFK G+ + RF + Sbjct: 3234 VMPEFKERLKNIK-VVEGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKH 3290 Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 L I D+ ED G Y C A N G + S RL Sbjct: 3291 TYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRL 3324 Score = 46.0 bits (104), Expect = 8e-04 Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 11/116 (9%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT-LNDFGFI 3753 P F +K NI V EG F RV+ G+P +++WF G+ + +R + + Sbjct: 3236 PEFKERLK-NIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809 L I + D G Y C A+N G K+ CS + D V E +P +S + ++ Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAG------KVQCSGRLD-VKERMVPPEISTDVLE 3341 Score = 45.6 bits (103), Expect = 0.001 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P P++ + V E++ A + G P EW R+ + + S R+ + G L Sbjct: 9 PQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATL 66 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 +K ED G Y C NE G A + + L V+ Sbjct: 67 TIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99 Score = 45.6 bits (103), Expect = 0.001 Identities = 39/158 (24%), Positives = 68/158 (43%), Gaps = 6/158 (3%) Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQ---APRFITQLNGPTKLSEGQSAH 1863 SL ++ E+ + + + + + ++ VN+ PRF ++ + EG+S Sbjct: 452 SLIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEELIGPRF-EKMKESFTVVEGESVE 510 Query: 1864 YECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923 R+ P P +EW +GK ++ + T A L I +DSG Y C A N Sbjct: 511 LVARVTGKPAPE--IEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARN 568 Query: 1924 NLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 G A + +L+VQ K+ + S L ++ E D Sbjct: 569 KSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGD 606 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+ + L+ + E EG +A ++ PT +EW K+G + S R G V Sbjct: 591 PEIVSELRPV-EATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEVK 647 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864 L I RA+D G YT N+LG A S ++V A Sbjct: 648 LTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIA 682 Score = 45.6 bits (103), Expect = 0.001 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 5/100 (5%) Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTY 1095 ++ +P F LK + I EG+S FE ++ TVEW+ + QI R I Sbjct: 1465 EVGSRPIFQQKLKAVSTI-EGESTRFEVKLSAMP--RPTVEWFKSSSQIYDGGRFTITEE 1521 Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 + G L I ED+G Y VVA N G+ A + V Sbjct: 1522 ENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV 1561 Score = 45.6 bits (103), Expect = 0.001 Identities = 38/154 (24%), Positives = 63/154 (40%), Gaps = 10/154 (6%) Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764 +VI AP + V E E + G P +EW ++G+ A+ R+ T D Sbjct: 1662 KVIGNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFD 1719 Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824 ++ D G Y C A N LG A +S+ L V + + + QK++ L Sbjct: 1720 GSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSKPEFK-------QKLRPL 1772 Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE 1858 E + + DV + P + G TK+++ Sbjct: 1773 EVVEGSEAKFDVRIKSYPKPE-VEWYRGTTKITD 1805 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/123 (25%), Positives = 64/123 (52%), Gaps = 8/123 (6%) Query: 2776 FISHLNNIV-CKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 FI + +V +GDN ++ ++E P +IEW+ N + + + +R + + S ++ Sbjct: 2159 FIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIA 2216 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVE--QAEE 2892 + + +DSG+Y CKA N+ G+ + ++ + + P +GL++VE + E+ Sbjct: 2217 LYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRP---EGTEPNIVSGLKSVEVKEGEQ 2273 Query: 2893 ARL 2895 A L Sbjct: 2274 AEL 2276 Score = 45.6 bits (103), Expect = 0.001 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 5/91 (5%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFT--PIYDFGY 4030 P F ++ ++ + E + KFE ++ G P +VEW+ +L ++RF + + GY Sbjct: 2352 PEFKEKL-TKVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETGY 2408 Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061 ++ G V ED+G Y C A N G +A Sbjct: 2409 YSLTVGEVVQEDAGMYKCIAVNKAGKSTCRA 2439 Score = 45.6 bits (103), Expect = 0.001 Identities = 61/263 (23%), Positives = 105/263 (39%), Gaps = 41/263 (15%) Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627 +++ E + P L VE+ EG F+ RL VEWY + + + F Sbjct: 2933 ELIIEPSVSPPSFRHRLTAVEVDEGDETRFDVRL---KKEPTSVEWYKEQQRIFTDGHFE 2989 Query: 1628 --ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685 E +L I + D+G Y C A+N G++ T +V +E + Sbjct: 2990 VIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLV-----------NERLI 3038 Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745 P + D Y+ D + A V P +IR +++ E++ + L V Sbjct: 3039 PPGFEGPDHGSYELQEG-DTITLDAVVKGNPYPEIRWYKDEFLAMESKKL-----MLSVR 3092 Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + N LT H V P+DSG Y C N++G A S T+ V++K Sbjct: 3093 --------DRKNSLTLYH-----------VIPKDSGVYKCVLKNKVGTATKSFTVDVEAK 3133 Query: 1806 ASLQLESQHESALQKIQQLEDSS 1828 S + + L++++ ++ S+ Sbjct: 3134 KSKGIIPEFFRQLRRVEAVQGST 3156 Score = 45.6 bits (103), Expect = 0.001 Identities = 34/101 (33%), Positives = 44/101 (43%), Gaps = 3/101 (2%) Query: 1171 EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY 1230 E K P+F+ PL + V EG+ I LECR+ P VEW +GR+ T + Sbjct: 3425 ESKKPAPLFIAPLHDQEVV-EGETIRLECRVR--ATPRPMVEWKKDGRTFKEDYHIYTEF 3481 Query: 1231 DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271 D L I A D G Y A N G + A + V E Sbjct: 3482 DGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKE 3522 Score = 45.6 bits (103), Expect = 0.001 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844 EGD F +VE S P K+EW ++ L +G R D L IT+ DSG Sbjct: 3540 EGDRAKF--HVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSG 3597 Query: 2845 IYTCKATNSKGSATTSGSL 2863 YTC A N G T G L Sbjct: 3598 KYTCIARNKAGENTCHGRL 3616 Score = 45.2 bits (102), Expect = 0.001 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 3/94 (3%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 +P+ P++ + +KE A + G T EW +D V S RI + G Sbjct: 8 RPQILQPLEG-VDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 LTIK D G Y C N G AT+ A L + Sbjct: 65 TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98 Score = 45.2 bits (102), Expect = 0.001 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P+ + ++ V+E E C + P EWYR+ + R ++ G +L Sbjct: 9 PQILQPLEGVDVKEDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSEVVNGMATL 66 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922 I AED GEY C N+ G +KA ++ + Sbjct: 67 TIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99 Score = 45.2 bits (102), Expect = 0.001 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 E ++ L + PN EW+++ + + R+KS G+ TL+I R +D G Y Sbjct: 22 EDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSEVVNGMATLTIKQTRAEDQGEY 79 Query: 2716 TCKATNLLGEAVSTASIKI 2734 C N G A S A + + Sbjct: 80 KCVLRNEHGTATSKAPLNV 98 Score = 45.2 bits (102), Expect = 0.001 Identities = 61/216 (28%), Positives = 81/216 (37%), Gaps = 40/216 (18%) Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493 EGE+ AR+T P ++EW +GK+++ + T +L I + +DSG Y Sbjct: 505 EGESVELVARVTGKPAP--EIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLY 562 Query: 3494 LCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAE 3553 C A N G A T + VQ K+ PKG PE Sbjct: 563 RCTARNKSGTADMTFQLDVQPKK--------PKG--------------------TAPEIV 594 Query: 3554 SGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG 3613 S P T D +LS S + +P +EW NG + R K G Sbjct: 595 SELRPVEATEGDDAVLSCTISG----KPVPT------IEWLKNGIRVKDSRRTKCDLVDG 644 Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 V L I D G YTC N G A KL+V Sbjct: 645 EVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680 Score = 45.2 bits (102), Expect = 0.001 Identities = 47/199 (23%), Positives = 76/199 (38%), Gaps = 28/199 (14%) Query: 804 VEWYKDGRPITASSR-ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 V+W+KD + R I + G SL I +R ED G+Y N+ G+ + A + + Sbjct: 1012 VDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI 1071 Query: 863 AARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIK 922 + + A PE+ E VP P+ P+ + + + Sbjct: 1072 --KEAIVA----PEEVDAAE------------------TVPIEGSAPKITKPL-ESVEVN 1106 Query: 923 EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHY 982 EG F+ G + VEW KD + S R+ + L K D G Y Sbjct: 1107 EG--EDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEY 1164 Query: 983 TCRAYNAIGQATTSANLTI 1001 C N G+A+T+ + + Sbjct: 1165 KCTVINEHGKASTTGEVKV 1183 Score = 45.2 bits (102), Expect = 0.001 Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 5/132 (3%) Query: 1408 LILESQHPS--GLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFE 1465 L+ + P G K + + + T + +V +P F + +E V EG FE Sbjct: 1151 LVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSRPEFKIKMSPVE-VTEGSEAAFE 1209 Query: 1466 CKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525 ++E L+VEWFK + R+ D + I ++ ED+G Y C A N Sbjct: 1210 VRVEGFP--KLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTA 1267 Query: 1526 GTDEVSCRLTCR 1537 G LT + Sbjct: 1268 GKTTSRADLTVK 1279 Score = 45.2 bits (102), Expect = 0.001 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV-A 2036 P+F + +KN +V EG + +P +VEW+ G+ ++ RF + + Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 L I ED GTY C A+N G+ + + V Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV 3326 Score = 45.2 bits (102), Expect = 0.001 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 9/113 (7%) Query: 1305 ITVMQA---PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--F 1359 +TV +A P F + +++ +EG + G +VEW + ++ G R Sbjct: 3518 LTVKEALIIPHFDHPIQDLDVIEGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSL 3575 Query: 1360 RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412 E L + + P DSG YTC A N+ GE +C R+ K+ ++ S Sbjct: 3576 EEDRETQMYFLTITNCKPTDSGKYTCIARNKAGE--NTCHGRLAVKEKMVTPS 3626 Score = 44.8 bits (101), Expect = 0.002 Identities = 60/249 (24%), Positives = 95/249 (38%), Gaps = 46/249 (18%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYV 2035 KP F +K + EG V + + P V WY + RF+ +V Sbjct: 103 KPSFTSKMKPVDAEEGQEVRFDVHVK--GSPKPDVVWYKGSTMIGTHERFQIVEAAEDHV 160 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 L I ED TY ATN VG+ + + ++V E+ Sbjct: 161 TLVISEVKLEDAETYKVVATNDVGKVTSRADLRVK---------------------ERQF 199 Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155 P+ I+EE+ P+ T GD C V P +I W+ NG+ + Sbjct: 200 APEFIDEERG---PIDATT---------GDEVTLTCSVS--GKPKPSITWYKNGKLLTDS 245 Query: 2156 HRY--RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR----NIIL 2209 + R++ + +V + L ED+ Y C+A NKLG+A +KV + + + Sbjct: 246 LKLDIRSSGERNWVTM--LSAKPEDTALYKCEAENKLGKASRAFDVKVKAPKGDAPSFTI 303 Query: 2210 DTQHPNGLE 2218 D H +E Sbjct: 304 DLTHVRAIE 312 Score = 44.8 bits (101), Expect = 0.002 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 2/97 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F + L V A+EG + ++ G P IEWLK + S R + F +L Sbjct: 299 PSFTIDLTHVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDFEKNVATL 356 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733 + + D+G Y A + +G A + A L V R+T Sbjct: 357 VIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERST 393 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 3/91 (3%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 +P +P I ++ + +G +A + G P P + W + + + + + + Sbjct: 585 KPKGTAPEIVSEL-RPVEATEGDDAVLSCTISGKPVPTIEWLKNGIRVKDSRR--TKCDL 641 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155 G+V L IK D+G+YTC RN+ G A Sbjct: 642 VDGEVKLTIKTTRADDQGDYTCIVRNELGSA 672 Score = 44.8 bits (101), Expect = 0.002 Identities = 58/241 (24%), Positives = 103/241 (42%), Gaps = 43/241 (17%) Query: 1032 RTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSA 1089 +T+ +V +P F LK K VEG+ + +VE P+ D +EWY I + Sbjct: 675 KTKLKVIAFARPEFRTKLKPV-KAVEGEEVQLDVKVEGYPKPD----IEWYRGTTMIVES 729 Query: 1090 NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRG 1149 R + + E+ G+Y++V + QL + T++ + T++ + Sbjct: 730 GRFKVMEE------------EEEDGLYSLVI----SKLQLDDTGTIKV---VATNASGKA 770 Query: 1150 LYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTM 1209 ++E +F P ++ +E P V+EG + ++ R++ +P Sbjct: 771 TSRADLEVKEREFA-PEFEGDE------------EGPIVVTEGNEVSIQLRVK--ANPNA 815 Query: 1210 RVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS-ADTGEYTVRAVNHLGSAHTSAIVR 1268 V+WF +GR + ++ + G IH +S DTG Y A N LG A S V+ Sbjct: 816 DVDWFKDGRPIYESTK-RDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVK 874 Query: 1269 V 1269 V Sbjct: 875 V 875 Score = 44.8 bits (101), Expect = 0.002 Identities = 38/148 (25%), Positives = 68/148 (45%), Gaps = 9/148 (6%) Query: 2216 GLEKIRQLEAQGHSTR---IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDP 2272 G K+ A G +T +EV+E + +P F + G V EG + +V+ +P Sbjct: 757 GTIKVVATNASGKATSRADLEVKEREFAP-EFEGDEEGPIVVTEGNEVSIQLRVKA--NP 813 Query: 2273 NLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISM 2332 N ++++ +G+ + + + I +L I ED G Y +A N LG + + + Sbjct: 814 NADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDV 873 Query: 2333 TVTAKGSIISESQRPEGLEKIRELESAE 2360 V KG + + P L K+R +E+ E Sbjct: 874 KVQVKG---PKGEAPIILSKLRPVETEE 898 Score = 44.8 bits (101), Expect = 0.002 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 2/115 (1%) Query: 1549 EAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDAT 1608 + G + V+ + K T V P + VE+ EG A FE R+ Sbjct: 1160 DIGEYKCTVINEHGKASTTGEVKVNVLSRPEFKIKMSPVEVTEGSEAAFEVRV--EGFPK 1217 Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT 1663 L+VEW+ ++ R+T T + + I + ED+G Y C A N G+ + Sbjct: 1218 LQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTS 1272 Score = 44.8 bits (101), Expect = 0.002 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 4093 SWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTG-HPKPRVMWLLNGNTI 4151 SW+V +Q ++ P+ + A ++EG A C+VT P+P + W +G I Sbjct: 1356 SWEVKVKQSAPKTTGE-EPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKI 1414 Query: 4152 VNGSRYKLTYDG 4163 SR K+ +DG Sbjct: 1415 RENSRIKMVFDG 1426 Score = 44.8 bits (101), Expect = 0.002 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 4/117 (3%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E+P + ++ E+ EG +L +T P ++W +G +++ R K +D Sbjct: 1371 EEPIIIRKLQAQEIDEGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIKMVFDGETC 1429 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092 +L I A +D G Y TN G A +T V V+ + +Q+LK + +E Sbjct: 1430 SLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGS---RPIFQQKLKAVSTIE 1483 Score = 44.8 bits (101), Expect = 0.002 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 2/114 (1%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 +P+ ++ L + EG +L C++ P ++W +G + SR K +D Sbjct: 1372 EPIIIRKLQ-AQEIDEGSTANLVCKVTA-AKPEPSIKWTRDGVKIRENSRIKMVFDGETC 1429 Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289 +L I AT D G Y V N G+A ++ V V E Q +A+ I+ Sbjct: 1430 SLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKLKAVSTIE 1483 Score = 44.8 bits (101), Expect = 0.002 Identities = 35/119 (29%), Positives = 63/119 (52%), Gaps = 8/119 (6%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FGI 3339 P F +++ V+ +EG+S FE +L + P VEWF + ++ G R+ + G+ Sbjct: 1470 PIFQQKLKAVST-IEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGV 1526 Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398 +L I E++G Y+ VA N LG+ +++A L+ E L + + + EG +EK + Sbjct: 1527 YVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV--NEVLTVPEFMDKA-EGPIEKTE 1582 Score = 44.8 bits (101), Expect = 0.002 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 6/106 (5%) Query: 903 PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962 PE Q P F + + Q+ + EGG + T V+W +DG PV RI+ Sbjct: 1958 PEG-QAPSFTSEMS-QVEVDEGGEVKLYFLISGYPKPT--VKWTRDGIPVFEDYRISMDS 2013 Query: 963 N-FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI 1007 + V L I++VT +D G Y C N G TT+ + IVT++ I Sbjct: 2014 SRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQV-IVTQRSI 2058 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 3/99 (3%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYIS 695 P F +K+V G + FE ++E G P + + + + I R++ + G Sbjct: 2060 PIFGQKMKNVEGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFV 2117 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734 L + + +D+GEY C AV+ G +K LHV TI Sbjct: 2118 LTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI 2156 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/118 (23%), Positives = 50/118 (42%), Gaps = 2/118 (1%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F+ + + L +GD +++ +E P I+W+HN + I A R + + Sbjct: 2157 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226 + + +DSG Y CKA N G + V R + +GL+ + E + Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVEVKEGE 2272 Score = 44.8 bits (101), Expect = 0.002 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 7/115 (6%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248 V EG+ LE + G PT +EW+ +G V R ++ + G L I + D G Sbjct: 2268 VKEGEQAELEFVVS--GTPTPTLEWYRDGLRVKESRRVRSTLENGIARLVITETWAEDMG 2325 Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLE-DAARRTKQVR 1302 Y + N LG TSA + +I + T + ++ + ++++ E D A+ +V+ Sbjct: 2326 TYKCQVRNDLGRTSTSAHLNII----VATRPEFKEKLTKVEVTEGDRAKFEVRVK 2376 Score = 44.8 bits (101), Expect = 0.002 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 4/117 (3%) Query: 1826 DSSRYQRREDVEVAVNQAPRFITQ--LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFN 1883 D+ + Q ++V P I+ L GP L+EG + P P++ +WY + Sbjct: 3314 DAGKVQCSGRLDVKERMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDL--QWYKD 3371 Query: 1884 GKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 G +++ S+ +L I+ V ED+G C A+N G A S + ++SK+ Sbjct: 3372 GVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKK 3428 Score = 44.8 bits (101), Expect = 0.002 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 3/83 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P+F PL + + EG+T +CR+ P VEW ++ + ++ I D + + Sbjct: 3431 PLFIAPLHD-QEVVEGETIRLECRVRATPRPM--VEWKKDGRTFKEDYHIYTEFDGQHCT 3487 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 + I + EDEG Y C A N G Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEG 3510 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 4/89 (4%) Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN---HTTLRVRNTQ 329 ++ +++G A+F ++ G P P VTW + +++ ++ + H H+ L Sbjct: 5135 KDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGY 5194 Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESP 358 K DSG Y +A+N G T G+L VE P Sbjct: 5195 K-DSGVYKCIAKNSAGQDTTVGHLFVEGP 5222 Score = 44.4 bits (100), Expect = 0.002 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 PQ + PL+ V E I G PT EW ++ + S R S G +L Sbjct: 9 PQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATL 66 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + +D GEY C + G A +KA L+V Sbjct: 67 TIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98 Score = 44.4 bits (100), Expect = 0.002 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 10/111 (9%) Query: 1302 REDITVMQ---APQF-SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357 R D+ V + AP+F I+ G V L C + G + W+ NGK + Sbjct: 189 RADLRVKERQFAPEFIDEERGPIDATTGDEVTLTCSVS--GKPKPSITWYKNGKLLTDSL 246 Query: 1358 RF--RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406 + R + E ++V + LS PED+ +Y C+A N+LG+A + ++V A K Sbjct: 247 KLDIRSSGERNWVTM--LSAKPEDTALYKCEAENKLGKASRAFDVKVKAPK 295 Score = 44.4 bits (100), Expect = 0.002 Identities = 35/127 (27%), Positives = 50/127 (39%), Gaps = 3/127 (2%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836 +S L + EGD+ C + PT IEW N + R K V L I Sbjct: 594 VSELRPVEATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEVKLTIK 651 Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLA 2896 T +D G YTC N GSA + L+ F T+ KA +E E + ++ Sbjct: 652 TTRADDQGDYTCIVRNELGSAESKTKLKVIAFARPEFRTKLKPVKA-VEGEEVQLDVKVE 710 Query: 2897 KGRRPSV 2903 +P + Sbjct: 711 GYPKPDI 717 Score = 44.4 bits (100), Expect = 0.002 Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 10/160 (6%) Query: 2196 TCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVF 2255 TC+L + R+ LD + + + + R+ V E S P F +L+ + + Sbjct: 1428 TCSLTI---RDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVG-SRPIFQQKLKAVSTI- 1482 Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FGYVSLDIQHCVPEDAG 2313 EG++ FE ++ + P +E++ + + RF IT + G L I+ EDAG Sbjct: 1483 EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDAG 1540 Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG-LEK 2352 Y V A N LG TS + V ++ + EG +EK Sbjct: 1541 TYKVVAYNNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEK 1580 Score = 44.4 bits (100), Expect = 0.002 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 5/101 (4%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696 V PIF LK+ +EG+ E ++ P +EWFK+ + G R T + Sbjct: 1466 VGSRPIFQQKLKAVST-IEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEE 1522 Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 G+ L I +D+G Y A N LG+ S A +++ + Sbjct: 1523 NSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNE 1563 Score = 44.4 bits (100), Expect = 0.002 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 3/92 (3%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD---GMYHF 4167 P+F AV+ EGE RF +++ P+P V W + + I +G R+ +T + G+Y Sbjct: 1470 PIFQQKLKAVSTIEGESTRFEVKLSAMPRPTVEWFKSSSQIYDGGRFTITEEENSGVYVL 1529 Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199 I T D G +V+ L+V Sbjct: 1530 VIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV 1561 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 4/129 (3%) Query: 1812 SQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIE 1869 + ++A+ K ++ + R D+ V Q P +G + EG + I Sbjct: 1829 TMEDAAMYKCVAFNEAGKTTCRADLTVIEKQQPPTFLGDDGTQTIIVKEGDDLNISATIA 1888 Query: 1870 PYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929 P P V WY +G+++ + T + L + ED+G Y C+A N LG Sbjct: 1889 GKPSPE--VSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVT 1946 Query: 1930 SSIRLNVQS 1938 + + V S Sbjct: 1947 KTYNVKVMS 1955 Score = 44.4 bits (100), Expect = 0.002 Identities = 26/124 (20%), Positives = 57/124 (45%), Gaps = 3/124 (2%) Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495 ++E +TI P+F+ + +++G + ++ LE ++EW+ N + + R + Sbjct: 2150 VEEELTI-PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQL 2206 Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555 + + ++ +DSG+Y C+AVN GT + + +GL+ + Sbjct: 2207 SFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSV 2266 Query: 1556 QVLE 1559 +V E Sbjct: 2267 EVKE 2270 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 2/116 (1%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 EE+ P F + + L +G+N ++ L P ++EWY N + + A SR + Sbjct: 2151 EEELTIPQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSF 2208 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGME 3529 + + +DSG Y C+A N G ++ VQ KR E + G++ Sbjct: 2209 ISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLK 2264 Score = 44.4 bits (100), Expect = 0.002 Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 2/116 (1%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F+ + + +G N L LE G P +EW+HN R + SR + + Sbjct: 2157 PQFIGDVPGVVELVQGDNYDLS--LEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLE 1292 + + + T D+G Y +AVN G+ + V + T+ ++ +++ E Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVEVKE 2270 Score = 44.4 bits (100), Expect = 0.002 Identities = 38/125 (30%), Positives = 59/125 (47%), Gaps = 12/125 (9%) Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502 +P V+ KS+E V EG+ E + L EW+++G V R R + G Sbjct: 2256 EPNIVSGLKSVE-VKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIA 2312 Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE--AGLEQIQVLE- 1559 L I + AED G Y C+ N +G S L +I+ +T+ E L +++V E Sbjct: 2313 RLVITETWAEDMGTYKCQVRNDLGRTSTSAHL------NIIVATRPEFKEKLTKVEVTEG 2366 Query: 1560 DRSKY 1564 DR+K+ Sbjct: 2367 DRAKF 2371 Score = 44.4 bits (100), Expect = 0.002 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 6/99 (6%) Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882 EP VS PP F ++ + V+E + RF+ R+ K++P +EWY+ + + + + + Sbjct: 2937 EPSVS-PPSFRHRLTAVEVDEGDETRFDVRL--KKEPT-SVEWYKEQQRIFTDGHFEVIE 2992 Query: 3883 --DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 + SL I D+G Y C A+N+ G+ T+A + Sbjct: 2993 GEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL 3031 Score = 44.4 bits (100), Expect = 0.002 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--RFGY 693 PP F L +V EG + F+ R++ +PT +EW K Q I F I Sbjct: 2942 PPSFRHRLTAVEVDEGDETRFDVRLKK--EPT-SVEWYKEQQRIFTDGHFEVIEGEEECL 2998 Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 SL + + + D+G Y C A++ +G + T+A L V R Sbjct: 2999 YSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036 Score = 44.4 bits (100), Expect = 0.002 Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 5/105 (4%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E+ P F PI+D + + EG A F +E G +VEWLK + + R++ Sbjct: 3520 VKEALIIPHFDHPIQD-LDVIEGDRAKFH--VEVSGKPAAKVEWLKGDQELRNGGRVSLE 3576 Query: 962 FN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 + LTI + D+G YTC A N G+ T L + K Sbjct: 3577 EDRETQMYFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAVKEK 3621 Score = 44.0 bits (99), Expect = 0.003 Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 7/116 (6%) Query: 2625 AMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684 A +K P ++ V P FT+ +K D EGQ V + V+ P+ + W+K Sbjct: 90 ATSKAP---LNVRVPVKPSFTSKMKPVDA-EEGQEVRFDVHVKGSPKPD--VVWYKGSTM 143 Query: 2685 LTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHW 2739 + T R + VTL I+ ++ +D+ Y ATN +G+ S A +++++R + Sbjct: 144 IGTHERFQIVEAAEDHVTLVISEVKLEDAETYKVVATNDVGKVTSRADLRVKERQF 199 Score = 44.0 bits (99), Expect = 0.003 Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 8/105 (7%) Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSANRIQT 1094 V++ KP F +K + EGQ F+ V+ P+ D V WY I + R Q Sbjct: 98 VRVPVKPSFTSKMKPVDA-EEGQEVRFDVHVKGSPKPD----VVWYKGSTMIGTHERFQI 152 Query: 1095 YHDF-GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 +V L I+ V+ ED+ Y VVA N G+ A + V+ R Sbjct: 153 VEAAEDHVTLVISEVKLEDAETYKVVATNDVGKVTSRADLRVKER 197 Score = 44.0 bits (99), Expect = 0.003 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 6/99 (6%) Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL--KSTFD 2696 Q AP F + G V L V + P+ I W+KNG LT +L +S+ + Sbjct: 198 QFAPEFIDEERGPIDATTGDEVTLTCSVSGKPKPS--ITWYKNGKLLTDSLKLDIRSSGE 255 Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 VT+ S + +D+ +Y C+A N LG+A +K++ Sbjct: 256 RNWVTML--SAKPEDTALYKCEAENKLGKASRAFDVKVK 292 Score = 44.0 bits (99), Expect = 0.003 Identities = 62/247 (25%), Positives = 92/247 (37%), Gaps = 42/247 (17%) Query: 2090 ELEKYERPKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHN 2148 +L K R ++ + P G P F LT + + EG+ + C+V P TI+W Sbjct: 279 KLGKASRAFDVKVKAPKGDAPSFTIDLTHVRAI-EGEESKLVCKVT--GKPAPTIEWLKG 335 Query: 2149 GQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII 2208 + R RT + L I T D+GTY A N G A Sbjct: 336 ELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTA--------------- 380 Query: 2209 LDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEP 2268 I +L+ Q ST+ E+E+ LR + G+ F+ ++ Sbjct: 381 ---------HSIAELQVQERSTKPEIED----------SLRDVS-ALPGERVKFKVRIG- 419 Query: 2269 VHDPNLRIEFYHNGKALQSAARFHITFDFGYV-SLDIQHCVPEDAGEYSVKAINALGHCT 2327 P ++E+ ++ RF I + V SL IQ DAG Y A N G Sbjct: 420 -GKPKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEAE 478 Query: 2328 SAISMTV 2334 S +TV Sbjct: 479 SMAQLTV 485 Score = 44.0 bits (99), Expect = 0.003 Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 2/74 (2%) Query: 793 QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRA-EDAGSYTVRAVNKL 851 QL ++P V+W+KDGRPI S++ I G +H+ + ED G Y A N+L Sbjct: 806 QLRVKANPNADVDWFKDGRPIYESTK-RDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRL 864 Query: 852 GEAISTASIRVAAR 865 G+A + ++V + Sbjct: 865 GKASRSFDVKVQVK 878 Score = 44.0 bits (99), Expect = 0.003 Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 2/106 (1%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E PEF + I EG R+ G +EW K R + SSRI Sbjct: 1561 VNEVLTVPEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFK 1618 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI 1007 +T+ + + D+G Y C A N G ++ + NL + KK I Sbjct: 1619 SRDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664 Score = 44.0 bits (99), Expect = 0.003 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 3/99 (3%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT-TMHDFGY 1767 QAP FT M + V E + + G PK V+W R+G+P+ R++ Sbjct: 1961 QAPSFTSEMSQVEVDEG--GEVKLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRVQG 2018 Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806 V L ++ V D G Y C N+ G T+ + V ++ Sbjct: 2019 VTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS 2057 Score = 44.0 bits (99), Expect = 0.003 Identities = 25/70 (35%), Positives = 39/70 (55%) Query: 793 QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852 ++T ++P +V WYKDG+ + + R+ L I + + ED+GSY A NKLG Sbjct: 2472 KVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLG 2531 Query: 853 EAISTASIRV 862 A + +IRV Sbjct: 2532 FADKSFTIRV 2541 Score = 44.0 bits (99), Expect = 0.003 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P+ + +K EV EG L +T PT +EWY + P++ R + L Sbjct: 2847 PEIVQRLKACEVPEGSSFKLRCRVT--GTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFL 2904 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 + L A D G YM A N +G T++ + ++ Sbjct: 2905 NFLETEARDEGRYMLVAKNHLGSVSTSAELIIE 2937 Score = 44.0 bits (99), Expect = 0.003 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 3/91 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+ ++ L+ E+ EG + ++T PT +EWYK P+ + R+ Sbjct: 2847 PEIVQRLKAC-EVPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQYF 2903 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860 LN + A D G Y + A N LG ++A + Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAEL 2934 Score = 44.0 bits (99), Expect = 0.003 Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 5/115 (4%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P+F + ++ E +G E ++ P ++ W +G+ + K YD L Sbjct: 3140 PEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKL 3197 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092 ED G Y C A+N GEA + +S+ + L + E RLK I+ +E Sbjct: 3198 TFYETQPEDEGDYTCVASNEAGEASSHASLVL--SKPLVMPEFKE-RLKNIKVVE 3249 Score = 44.0 bits (99), Expect = 0.003 Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 3/96 (3%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKT-INDFGFVI 3616 PEF ++ + E A F R+ + +VEWF GK + + +R + + Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 L I V D G Y C A+N G+ S +L VK R Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329 Score = 44.0 bits (99), Expect = 0.003 Identities = 36/116 (31%), Positives = 56/116 (48%), Gaps = 12/116 (10%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRF-KLTSDFGFVTLDLVDVYERD 2980 ++VEG + V K +P+ K+EW+ GK ++ +RF + TL + DV D Sbjct: 3246 KVVEGD--EAQFSVRVKGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYTLTISDVAMED 3303 Query: 2981 SGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK-GTEGLE--KIQNLEDSLR 3033 G Y C A N G+ V C+ + ++ ER P+ T+ LE + N D LR Sbjct: 3304 FGTYKCVASNDAGK------VQCSGRLDVKERMVPPEISTDVLEGPALLNEGDDLR 3353 Score = 44.0 bits (99), Expect = 0.003 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 6/115 (5%) Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962 V +++ P P +I P+ + ++VEG+ + LE +V P +EW +G+ ++ Sbjct: 3423 VIESKKPAPLFIAPLH-DQEVVEGETIRLECRVRATPRP--MVEWKKDGRTFKEDYHIYT 3479 Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL-IERTQHP 3016 D TL + D G Y C A NK G S T K+ L I HP Sbjct: 3480 EFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRG--RSVAQLTVKEALIIPHFDHP 3532 Score = 44.0 bits (99), Expect = 0.003 Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 7/130 (5%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPV 508 L I+ T+ D G TC A N +G + C +I V AP V++ +T G + Sbjct: 5930 LCISCATIEDEGEYTCRASNPAGSCS--CTAELI----VDAPAKVDQAATPGSGVVGGKI 5983 Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568 L G P P TW + + + I T S+L I R + D Y+ +N Sbjct: 5984 TLTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVKND 6043 Query: 569 AGSTATRARL 578 G + +L Sbjct: 6044 GGEDSCVVKL 6053 Score = 43.6 bits (98), Expect = 0.004 Identities = 38/126 (30%), Positives = 56/126 (44%), Gaps = 7/126 (5%) Query: 1540 TDIVRSTQ-NEAGLEQIQVLEDRSKYHRTD--MVDEVTTQAPICTTSLKNVEIKEGQRAH 1596 T +++ T+ +AG ++ D H V E +T+ P SL++V G+R Sbjct: 355 TLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTK-PEIEDSLRDVSALPGERVK 413 Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPE-DSGTYTCRAI 1655 F+ R+ KVEW ++ G RFT V I+ L E D+G Y C A Sbjct: 414 FKVRI--GGKPKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVAT 471 Query: 1656 NALGEA 1661 N GEA Sbjct: 472 NEAGEA 477 Score = 43.6 bits (98), Expect = 0.004 Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 5/115 (4%) Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871 E G K + I P+F T++K E E V+ + +VE PK IEWYR + Sbjct: 668 ELGSAESKTKLKVIAFARPEFRTKLKPVKAVEGEEVQLDVKVEGY--PKPDIEWYRGTTM 725 Query: 3872 LPSGHRYRTVYDM---GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 + R++ + + G SL I + +D+G A N G+ ++A + K+ Sbjct: 726 IVESGRFKVMEEEEEDGLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKE 780 Score = 43.6 bits (98), Expect = 0.004 Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 9/162 (5%) Query: 2216 GLEKIRQLEAQGHSTR---IEVEE--PKIS--PPRFVTELRGTTHVFEGKTAHFECQVEP 2268 G+ K + A G ++R ++V++ PK + P + +L+ + EG TA+ C+V Sbjct: 1340 GVYKCQATNAAGSASRSWEVKVKQSAPKTTGEEPIIIRKLQAQ-EIDEGSTANLVCKVTA 1398 Query: 2269 VHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328 P I++ +G ++ +R + FD SL I+ +D G Y V N G +S Sbjct: 1399 AK-PEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASS 1457 Query: 2329 AISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370 + V GS Q+ + + I + K +P P Sbjct: 1458 TCRVLVNEVGSRPIFQQKLKAVSTIEGESTRFEVKLSAMPRP 1499 Score = 43.6 bits (98), Expect = 0.004 Identities = 53/221 (23%), Positives = 88/221 (39%), Gaps = 41/221 (18%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 +F L + EG++ FE + PT +EWF ++ + G R+ Sbjct: 1471 IFQQKLKAVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRF------------ 1516 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894 T T EE+SG+Y ++ + +G+ + N+ GK +A+ + E Sbjct: 1517 -TITEEENSGVYVLVIEDT--NIEDAGTYKVVAYNNL--------GKVTSQALLRVNEVL 1565 Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954 PE++ + EG L L +V K P+L EW+ + L Sbjct: 1566 TV--------------PEFMDKAEGPIEKTEGDDLELTVRVRGKPQPEL--EWFKYDRTL 1609 Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995 + SR S T+ + D+ DSG+Y C A NK G + Sbjct: 1610 WKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKAGSS 1650 Score = 43.6 bits (98), Expect = 0.004 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 ++EG T +C + G P +EW+++ + R+ T D S+T + + D+G Sbjct: 1679 VKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDG 1736 Query: 2448 VYMCRASNLLG 2458 Y C A+N LG Sbjct: 1737 EYKCVATNPLG 1747 Score = 43.6 bits (98), Expect = 0.004 Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 3/103 (2%) Query: 902 VPESTQKPEFKTPIKDQ-ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT 960 V E Q P F Q I +KEG + A + G + V W KDGR V S + T Sbjct: 1855 VIEKQQPPTFLGDDGTQTIIVKEGDDLNISATIA--GKPSPEVSWYKDGRLVLDSIKQET 1912 Query: 961 FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003 L + + + DAG Y C A N +G T + N+ +++ Sbjct: 1913 RKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKVMS 1955 Score = 43.6 bits (98), Expect = 0.004 Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 4/102 (3%) Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625 +L+ +N E R P + +EW+HN + + SRV+ + + V Sbjct: 2168 ELVQGDNYDLSLEVRGTPRPE----IEWYHNERLIYATSRVQLSFISSKATIALYNVTLD 2223 Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKS 3667 D+GLY CKA N G + + V+ ++ EP + S KS Sbjct: 2224 DSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKS 2265 Score = 43.6 bits (98), Expect = 0.004 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502 +P + R + ++ IEG+ + EC++ + + W K+G +R + D Sbjct: 2550 EPTILQRLQPVDT-IEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVC 2606 Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 L I D+ D GIY C A N G+ S LT Sbjct: 2607 TLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELT 2639 Score = 43.6 bits (98), Expect = 0.004 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 6/98 (6%) Query: 1171 EISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227 E KSK P F + L V +G EC++ G P ++ W +G+ + + K Sbjct: 3131 EAKKSKGIIPEFFRQLRRVEAV-QGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIK 3187 Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265 +YD L D G+YT A N G A + A Sbjct: 3188 PFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHA 3225 Score = 43.2 bits (97), Expect = 0.005 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 3/94 (3%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 +P +QPL V E +N L C + G PT EW+ + V R K+ G Sbjct: 8 RPQILQPLEGVD-VKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64 Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269 L I + D GEY N G+A + A + V Sbjct: 65 TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98 Score = 43.2 bits (97), Expect = 0.005 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 6/117 (5%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827 +P F ++ + + +EG+ F+ + P V WYK I R + + Sbjct: 103 KPSFTSKMKPV-DAEEGQEVRFDVHVK--GSPKPDVVWYKGSTMIGTHERFQIVEAAEDH 159 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKT 884 V+L I ++ EDA +Y V A N +G+ S A +RV R A I E+R I+ T Sbjct: 160 VTLVISEVKLEDAETYKVVATNDVGKVTSRADLRVKERQ--FAPEFIDEERGPIDAT 214 Score = 43.2 bits (97), Expect = 0.005 Identities = 21/60 (35%), Positives = 31/60 (51%) Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 T+EW NG ++ + R + G V L I + RA+D G YT + RN G A+ + V Sbjct: 621 TIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680 Score = 43.2 bits (97), Expect = 0.005 Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234 S+P F +S P V+EG E R+E G P ++VEWF + R+ D Sbjct: 1187 SRPEFKIKMS-PVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNR 1243 Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 + I + T D G Y A N G + A + V ER Sbjct: 1244 YTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKER 1281 Score = 43.2 bits (97), Expect = 0.005 Identities = 36/148 (24%), Positives = 61/148 (41%), Gaps = 4/148 (2%) Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFS 1314 V +G +HT IVR V Q A + + KQ T + P Sbjct: 1320 VRAIGDSHTCFIVRAKLSDAGVYKCQATNAAGSASRSWEV--KVKQSAPK-TTGEEPIII 1376 Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374 R L E EG+ +L C++ + ++W +G I+ R + ++ + +L + Sbjct: 1377 RKLQAQEIDEGSTANLVCKVTAAKPEPS-IKWTRDGVKIRENSRIKMVFDGETCSLTIRD 1435 Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRV 1402 +D GVY TN+ G A ++C + V Sbjct: 1436 ATLDDEGVYKVTLTNEYGTASSTCRVLV 1463 Score = 43.2 bits (97), Expect = 0.005 Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 2/116 (1%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P F + + I+ EG + RV G P ++WF R SR++ + Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFKSRDNKFT 1625 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810 + + + D+G Y C A NK GS++ T + K+ I + + +++KE Sbjct: 1626 MTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVIGNAPDIITHLISKEVKE 1681 Score = 43.2 bits (97), Expect = 0.005 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 11/135 (8%) Query: 3966 DVDKKQ----PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR 4021 DV KK+ P +T + S+ + E T EC ++ G P +EW+ +G R Sbjct: 1657 DVQKKKVIGNAPDIITHLISK-EVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRR 1713 Query: 4022 FTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHM 4081 +D ++ F D GEY C ATN G ++ A + T + + + + Sbjct: 1714 VMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVT----VPSKPEFKQKL 1769 Query: 4082 KSIEKIREMEASWQV 4096 + +E + EA + V Sbjct: 1770 RPLEVVEGSEAKFDV 1784 Score = 43.2 bits (97), Expect = 0.005 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 6/103 (5%) Query: 2100 IEEEQPGQRPVFL-TALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158 IE++QP P FL T +KEGD + + P + W+ +G+ + + Sbjct: 1856 IEKQQP---PTFLGDDGTQTIIVKEGDDLNISATIA--GKPSPEVSWYKDGRLVLDSIKQ 1910 Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 T L + ED+G+Y C+A NKLG T +KV Sbjct: 1911 ETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKV 1953 Score = 43.2 bits (97), Expect = 0.005 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 9/113 (7%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 ++ EG+ LE V P L EWY +G +++ R + T + G L + + + D Sbjct: 2267 EVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDM 2324 Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRK 3034 G Y C+ N G TS+ + N+I T+ P+ E L K++ E K Sbjct: 2325 GTYKCQVRNDLGRTSTSAHL------NIIVATR-PEFKEKLTKVEVTEGDRAK 2370 Score = 43.2 bits (97), Expect = 0.005 Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Query: 2098 KPIEEEQPGQR-PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156 KP +PG+ P + L + E + EG CRV P TI+W+ + ++ Sbjct: 2835 KPKRGLKPGEAAPEIVQRLKACE-VPEGSSFKLRCRVTGTPTP--TIEWYKSNMPLKPNG 2891 Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199 R H L+ L T A D G YM A N LG + L Sbjct: 2892 RVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAEL 2934 Score = 43.2 bits (97), Expect = 0.005 Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 10/143 (6%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG + C V + PT IEW+ +N PL R H L+ T D G Y Sbjct: 2860 EGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDEGRY 2917 Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVE--QAEEARLAKGRRPSVP 2904 A N GS +TS L I P + L AVE + +E R + Sbjct: 2918 MLVAKNHLGSVSTSAEL------IIEPSVSPPSFRHRLTAVEVDEGDETRFDVRLKKEPT 2971 Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQ 2927 E+ K + I +++EG+ Sbjct: 2972 SVEWYKEQQRIFTDGHFEVIEGE 2994 Score = 43.2 bits (97), Expect = 0.005 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THDFGFVTLDINSVVANDAGL 2580 EG A + RV G+P + EW+ G ++K +RF + + TL I+ V D G Sbjct: 3249 EGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYTLTISDVAMEDFGT 3306 Query: 2581 YMCKAINRAG 2590 Y C A N AG Sbjct: 3307 YKCVASNDAG 3316 Score = 43.2 bits (97), Expect = 0.005 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 2/94 (2%) Query: 2497 RSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSR 2556 R + +R I T VL GP+ L EG V G+P +WY +GV ++ + Sbjct: 3323 RLDVKERMVPPEISTDVLEGPALLNEGDDLRLVVSVT--GNPIPDLQWYKDGVLIRRSTH 3380 Query: 2557 FRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 + +L I VV D G+ C A+N AG Sbjct: 3381 ISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAG 3414 Score = 43.2 bits (97), Expect = 0.005 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982 L EG L L V PDL +WY +G ++ + + L+S +L ++ V D+G Sbjct: 3346 LNEGDDLRLVVSVTGNPIPDL--QWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTG 3403 Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSK 3006 + C A N G A S TV SK Sbjct: 3404 VIKCVAMNPAGSASKSFTVVIESK 3427 Score = 43.2 bits (97), Expect = 0.005 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 4/112 (3%) Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI--KNSPDFQ-IHTF 4462 + + P+FT ++ + + + ARF+ G P P + W RE+ I + P + +H Sbjct: 5123 RKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALHEG 5182 Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP 4514 S+LI + +DS V+ +A+N G +L VE + G+ P Sbjct: 5183 EVHSLLITEGGY-KDSGVYKCIAKNSAGQDTTVGHLFVEGPEFKPIKGVQKP 5233 Score = 42.7 bits (96), Expect = 0.007 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 2/84 (2%) Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839 L + KE +N C + S PT EW+ ++ + R KS +L I T Sbjct: 15 LEGVDVKEDENAILSCTI--SGTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTR 72 Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863 ED G Y C N G+AT+ L Sbjct: 73 AEDQGEYKCVLRNEHGTATSKAPL 96 Score = 42.7 bits (96), Expect = 0.007 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 2/108 (1%) Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354 A R V+ AP F+ L ++ +EG L C++ G +EW P+ Sbjct: 283 ASRAFDVKVKAPKGDAPSFTIDLTHVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVT 340 Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 T R R +E + L + D+G Y A N G A + L+V Sbjct: 341 TSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQV 388 Score = 42.7 bits (96), Expect = 0.007 Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 3/71 (4%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFV-TLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999 P K+EW V+E G RF + + V +L + D+ E D+G Y C A N+ GEA S Sbjct: 422 PKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEA--ES 479 Query: 3000 TVYCTSKDNLI 3010 T + LI Sbjct: 480 MAQLTVNEELI 490 Score = 42.7 bits (96), Expect = 0.007 Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 10/165 (6%) Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLT 1074 G K+ + + + R + EVK + P F G +G + EG + RV+ + Sbjct: 757 GTIKVVATNASGKATSRADLEVKEREFAPEFEGDEEGPIVVTEGNEVSIQLRVKANPNAD 816 Query: 1075 MTVEWYFNGKQITSANR--IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSAS 1132 V+W+ +G+ I + + I+ + +A+ ++S+ ED+GVY A N G+A S Sbjct: 817 --VDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSL--EDTGVYKCEASNRLGKASRSFD 872 Query: 1133 MTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKP 1177 + V+ + + I + K R +E + E + K P Sbjct: 873 VKVQVKGPKGEAPI---ILSKLRPVETEEGEETKLKCTFTGKPAP 914 Score = 42.7 bits (96), Expect = 0.007 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GY 2433 RP+F Q ++N++ + G+ F+ ++ G P V + R + I D R + + G Sbjct: 2059 RPIFGQKMKNVEG-RIGEDVRFEIQV--EGTPVPAVTFHRESEQIYDGGRYSIVEEENGL 2115 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459 +TI + R ED G Y C A N GE Sbjct: 2116 FVLTIRNTRPEDAGEYQCIAVNGAGE 2141 Score = 42.7 bits (96), Expect = 0.007 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVA 1769 P+F MK++ + FE ++ G P V + R I R + + + G Sbjct: 2060 PIFGQKMKNVEGRIGEDVRFEIQV--EGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFV 2117 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 L ++ PED+G Y C A+N GE + L V+ + ++ Sbjct: 2118 LTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI 2156 Score = 42.7 bits (96), Expect = 0.007 Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 5/103 (4%) Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK--TY 1229 I ++P F + L+ V+EG E R++ G P VEW+H + RF+ + Sbjct: 2347 IVATRPEFKEKLTKVE-VTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESV 2403 Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 + G+ +L + D G Y AVN G + A + V ER Sbjct: 2404 KETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446 Score = 42.7 bits (96), Expect = 0.007 Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 9/129 (6%) Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290 R+EV +P P + L+ + EG+ EC+V +P I + +G + R Sbjct: 2540 RVEVPKPTGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNR 2596 Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350 FD +L I+ D G Y A N+ G S+ +TV + RP L Sbjct: 2597 IKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTV------LEREARPRIL 2650 Query: 2351 EKIRELESA 2359 EK+++++S+ Sbjct: 2651 EKLQDVDSS 2659 Score = 42.7 bits (96), Expect = 0.007 Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 4/120 (3%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P + LK ++ EG S F+ R T T+EWY + + R+ H Sbjct: 2847 PEIVQRLKAC-EVPEGSS--FKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162 L+ A D G Y +VA+N G SA + +E S S HR + +E++F Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVS-PPSFRHRLTAVEVDEGDETRF 2962 Score = 42.3 bits (95), Expect = 0.009 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 3274 PSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT 3333 P P P+ +++++ V + EG A + P +EW NG ++ R + Sbjct: 583 PKKPKGTAPEIVSELRPV-EATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKC 639 Query: 3334 FHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373 G V L I ++ G+Y C+ N+LG +K LK Sbjct: 640 DLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLK 679 Score = 42.3 bits (95), Expect = 0.009 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100 P F+ +G + EG RV +PQ +L EW+ + + ++RI Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVRGKPQPEL----EWFKYDRTLWKSSRINFKSRDNK 1623 Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141 + ++ + +DSG+Y VARN AG + + ++ V+ + I Sbjct: 1624 FTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664 Score = 42.3 bits (95), Expect = 0.009 Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P +T S E V EG V EC + N +EW+K+G T R D + Sbjct: 1668 PDIITHLISKE-VKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMTTFDGSVAS 1724 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 + D D G Y C A N +G+ + S RLT Sbjct: 1725 VTFTDAQGFDDGEYKCVATNPLGSAQSSARLT 1756 Score = 42.3 bits (95), Expect = 0.009 Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 7/134 (5%) Query: 3682 REEITIEDEKPNPPRFTVEI-KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740 R ++T+ EK PP F + I V EG ++ + G P+ + W+ +GR Sbjct: 1850 RADLTVI-EKQQPPTFLGDDGTQTIIVKEGDDLNISATI--AGKPSPEVSWYKDGRLVLD 1906 Query: 3741 GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800 + T L + DAG Y C A NK G+ T T + + E Q P Sbjct: 1907 SIKQETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKVMSTAP---EGQAP 1963 Query: 3801 QGMSGEKIKELERG 3814 S E++ G Sbjct: 1964 SFTSEMSQVEVDEG 1977 Score = 42.3 bits (95), Expect = 0.009 Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 14/142 (9%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGFI 3753 P FT E+ ++V EGG V + PT++ W +G P R+ + + Sbjct: 1963 PSFTSEMSQ-VEVDEGGEVKLYFLISGYPKPTVK--WTRDGIPVFEDYRISMDSSRVQGV 2019 Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813 L I + D G Y C N+ GS TTT ++ IV + + + + G+K+K +E Sbjct: 2020 TLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQV-------IVTQRSI-RPIFGQKMKNVE- 2070 Query: 3814 GRI-SDAPKEEPIVSTPPKFIT 3834 GRI D E + TP +T Sbjct: 2071 GRIGEDVRFEIQVEGTPVPAVT 2092 Score = 42.3 bits (95), Expect = 0.009 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 3/91 (3%) Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-G 3885 S P F ++K+ E VRFE +VE P + ++R + + G RY V + G Sbjct: 2057 SIRPIFGQKMKNVEGRIGEDVRFEIQVEGTPVPA--VTFHRESEQIYDGGRYSIVEEENG 2114 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTK 3916 L I ED+GEY C AVN GE +K Sbjct: 2115 LFVLTIRNTRPEDAGEYQCIAVNGAGEVTSK 2145 Score = 42.3 bits (95), Expect = 0.009 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEY 1917 G+ +E ++E P P V ++ + + G RY + G L I ED+GEY Sbjct: 2074 GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEY 2131 Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942 C A+N G+ S L+V+ + +I Sbjct: 2132 QCIAVNGAGEVTSKGYLHVEEELTI 2156 Score = 42.3 bits (95), Expect = 0.009 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS--DFGFVTLDLVDVYERDSGIYTCKAYNK 2991 +V K P ++EWY + RF++ S + G+ +L + +V + D+G+Y C A NK Sbjct: 2372 EVRVKGYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNK 2431 Query: 2992 RGEA 2995 G++ Sbjct: 2432 AGKS 2435 Score = 42.3 bits (95), Expect = 0.009 Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 2/98 (2%) Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636 AP LK E+ EG + F+ R T +EWY +N PLK R + Sbjct: 2846 APEIVQRLKACEVPEG--SSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903 Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674 L+ + D G Y A N LG TS I+ S Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVS 2941 Score = 42.3 bits (95), Expect = 0.009 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 10/135 (7%) Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601 S TVD +++ G PEF + + S+A FEC++ ++ W +GK L Sbjct: 3125 SFTVDVEAKKSK-GIIPEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELA 3181 Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL 3661 +K D L D G YTC A+N GEA+ L ++ +P + Sbjct: 3182 IPRYIKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASL-------VLSKPLV 3234 Query: 3662 PSHFKSGTESIQKLE 3676 FK ++I+ +E Sbjct: 3235 MPEFKERLKNIKVVE 3249 Score = 42.3 bits (95), Expect = 0.009 Identities = 40/125 (32%), Positives = 52/125 (41%), Gaps = 6/125 (4%) Query: 3529 EGTIDKIAA-LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587 EG + IA EG +V LT + E+ P F DL + E A F + Sbjct: 3498 EGAYECIAKNKEGRGRSVAQLTVK-EALIIPHFDHPIQDLDVIEGDRAKFHVEVS--GKP 3554 Query: 3588 SMRVEWFHNGKPLLTGSRVKTIND--FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSC 3645 + +VEW + L G RV D L I D+G YTC A N+ GE T Sbjct: 3555 AAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSGKYTCIARNKAGENTCHG 3614 Query: 3646 KLQVK 3650 +L VK Sbjct: 3615 RLAVK 3619 Score = 42.3 bits (95), Expect = 0.009 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 7/130 (5%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD--FGY 1100 P F P++ + ++EG A F VE VEW +++ + R+ D Sbjct: 3527 PHFDHPIQDLD-VIEGDRAKFH--VEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583 Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEES 1160 L I + + DSG YT +ARN AGE + V + + T S G ++ + E Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAV--KEKMVTPSFAEGDADEPCEVWEG 3641 Query: 1161 KFVEPMYQIE 1170 ++ + QI+ Sbjct: 3642 APIKLIVQIK 3651 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 5/98 (5%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFGL 2699 P F ++ D ++EG +V + P K+EW K L G R L+ + + Sbjct: 3527 PHFDHPIQDLD-VIEGDRAKFHVEVSGK--PAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 L+I + + DSG YTC A N GE + ++++ Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAVKEK 3621 Score = 42.3 bits (95), Expect = 0.009 Identities = 19/67 (28%), Positives = 31/67 (46%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P+P W+R + +K+ I T +S L I ++ D + V +N GG C Sbjct: 5991 GNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVKNDGGEDSCV 6050 Query: 4496 ANLVVEE 4502 L V++ Sbjct: 6051 VKLTVDD 6057 Score = 41.9 bits (94), Expect = 0.012 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449 EG A C + G P +EW +N ++DS R G V +TI R +D+G Y Sbjct: 604 EGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDY 661 Query: 2450 MCRASNLLG 2458 C N LG Sbjct: 662 TCIVRNELG 670 Score = 41.9 bits (94), Expect = 0.012 Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 IV EG+ + + V+ + P ++WF + +P+ T+ +L I + ED Sbjct: 795 IVVTEGNEVSIQLRVKAN--PNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLED 852 Query: 2843 SGIYTCKATNSKGSATTS 2860 +G+Y C+A+N G A+ S Sbjct: 853 TGVYKCEASNRLGKASRS 870 Score = 41.9 bits (94), Expect = 0.012 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 5/98 (5%) Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969 +PE+ I ++ ++ EG E +VE P L++EW+ +E R+ T+D Sbjct: 1188 RPEFKIKMSPV-EVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244 Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007 T+ + +V D+G Y C A N G+ T+S T K+ Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGK--TTSRADLTVKE 1280 Score = 41.9 bits (94), Expect = 0.012 Identities = 22/68 (32%), Positives = 36/68 (52%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G+P ++W ++GV I S ++ +L + V PED+G C A+N G A S Sbjct: 3360 GNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKS 3419 Query: 1798 STLFVQSK 1805 T+ ++SK Sbjct: 3420 FTVVIESK 3427 Score = 41.5 bits (93), Expect = 0.016 Identities = 23/59 (38%), Positives = 28/59 (47%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 +EWLK PV S R+ T F L IK + DAG Y A N G A + A L + Sbjct: 330 IEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQV 388 Score = 41.5 bits (93), Expect = 0.016 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 6/101 (5%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+ ++DV+ L G+ F+ R+ P KVEW + G R+ + V Sbjct: 395 PEIEDSLRDVSAL-PGERVKFKVRIGGKPKP--KVEWRKGKSVIEDGERFTIAEESDEVF 451 Query: 3342 LDILYCYEE-NSGEYECVATNKLGRDSTKANLKCTSKENLI 3381 I+ EE ++G Y+CVATN+ G + A L T E LI Sbjct: 452 SLIIQDLEETDAGRYKCVATNEAGEAESMAQL--TVNEELI 490 Score = 41.5 bits (93), Expect = 0.016 Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 5/112 (4%) Query: 3403 SMVRRKDTSVEEEK--GKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460 S R + V+++K G AP L + E ++EG E ++ PN +EWY +G Sbjct: 1649 SSSRTFNLDVQKKKVIGNAPDIITHLISKE-VKEGGTVTLECTVSGKPAPN--IEWYKDG 1705 Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 A R T D + + D GEY C A N G A ++A + V Sbjct: 1706 LRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757 Score = 41.5 bits (93), Expect = 0.016 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 8/143 (5%) Query: 902 VPESTQKPEFKT-PIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT 960 V E PEF+T + I + EGG + L + +V W KDG+ + R+ Sbjct: 2443 VNERQFAPEFETGEERGPIVVPEGGETTLKVTLR--ANPKPQVIWYKDGKHTSENIRLDV 2500 Query: 961 FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020 L I + + D+G Y C A N +G A S + + K + P L+++ Sbjct: 2501 RSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADKSFTIRVEVPK---PTGEEPTILQRL 2557 Query: 1021 QYLEDASRYSKRTEEEVKITQKP 1043 Q ++ + + E +++ KP Sbjct: 2558 QPVDTIE--GEAIKMECRVSGKP 2578 Score = 41.5 bits (93), Expect = 0.016 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 2/91 (2%) Query: 2916 PIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVD 2975 P ++L EG + L+ V K +P +I WY + + + + L+ +L L Sbjct: 3045 PDHGSYELQEGDTITLDAVV--KGNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYH 3102 Query: 2976 VYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006 V +DSG+Y C NK G A S TV +K Sbjct: 3103 VIPKDSGVYKCVLKNKVGTATKSFTVDVEAK 3133 Score = 41.5 bits (93), Expect = 0.016 Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 3/101 (2%) Query: 2234 VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI 2293 V E K P F+ L V EG+T EC+V P +E+ +G+ + + Sbjct: 3423 VIESKKPAPLFIAPLHDQ-EVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYT 3479 Query: 2294 TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 FD + +L I+ ED G Y A N G S +TV Sbjct: 3480 EFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV 3520 Score = 41.1 bits (92), Expect = 0.021 Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 2/92 (2%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 PQ + L ++ E N L C + G T EW+ + ++ R + L Sbjct: 9 PQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATL 66 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 + ED G Y C N+ G A + L V Sbjct: 67 TIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98 Score = 41.1 bits (92), Expect = 0.021 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 10/129 (7%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 ++ ++PK + P V+ELR EG A C + P IE+ NG ++ + R Sbjct: 581 VQPKKPKGTAPEIVSELR-PVEATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRT 637 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 G V L I+ +D G+Y+ N LG S + V A RPE Sbjct: 638 KCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIA-------FARPEFRT 690 Query: 2352 KIRELESAE 2360 K++ +++ E Sbjct: 691 KLKPVKAVE 699 Score = 41.1 bits (92), Expect = 0.021 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 5/94 (5%) Query: 1435 IIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494 ++ V +P F + K++ + IEG+ FE KL + VEWFK+ + G RF Sbjct: 1461 VLVNEVGSRPIFQQKLKAV-STIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFT 1517 Query: 1495 PIHD--FGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 + G L I D ED+G Y A N +G Sbjct: 1518 ITEEENSGVYVLVIEDTNIEDAGTYKVVAYNNLG 1551 Score = 41.1 bits (92), Expect = 0.021 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 6/97 (6%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF--- 2164 +P F L LE + EG A F+ R++ P ++W+ KI R++ T + Sbjct: 1762 KPEFKQKLRPLE-VVEGSEAKFDVRIKSYPKPE--VEWYRGTTKITDSLRHQITEPYEGD 1818 Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 +L IL T ED+ Y C A N+ G+ L V Sbjct: 1819 DTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTV 1855 Score = 41.1 bits (92), Expect = 0.021 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 6/96 (6%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHN-GQKIRAGHRYRTTHDF-G 2165 RP+F + ++E + G+ FE +VE P +T FH ++I G RY + G Sbjct: 2059 RPIFGQKMKNVEG-RIGEDVRFEIQVEGTPVPAVT---FHRESEQIYDGGRYSIVEEENG 2114 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 L I T ED+G Y C A N GE + L V Sbjct: 2115 LFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHV 2150 Score = 41.1 bits (92), Expect = 0.021 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 3/90 (3%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-L 2833 +F + N+ + G+++ FE VE + P + + ++ + G RY + + + L Sbjct: 2061 IFGQKMKNVEGRIGEDVRFEIQVEGT--PVPAVTFHRESEQIYDGGRYSIVEEENGLFVL 2118 Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 I +T ED+G Y C A N G T+ G L Sbjct: 2119 TIRNTRPEDAGEYQCIAVNGAGEVTSKGYL 2148 Score = 41.1 bits (92), Expect = 0.021 Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 3/73 (4%) Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF-GYVSLDIQHCVPEDAGEY 2315 G+ FE QVE P + F+ + + R+ I + G L I++ PEDAGEY Sbjct: 2074 GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEY 2131 Query: 2316 SVKAINALGHCTS 2328 A+N G TS Sbjct: 2132 QCIAVNGAGEVTS 2144 Score = 41.1 bits (92), Expect = 0.021 Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 3/101 (2%) Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471 V + G+ P L ++ + EGE E R++ +P + W +G +R +T Sbjct: 2543 VPKPTGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKT 2599 Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 + D L I D G Y C A N+ G A ++A + V Sbjct: 2600 YFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTV 2640 Score = 41.1 bits (92), Expect = 0.021 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 5/86 (5%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT--SIFNFGY 827 P F P+QDL ++ EG A F +++ P +VEW K + + R++ Sbjct: 3527 PHFDHPIQDL-DVIEGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGE 853 L I + + D+G YT A NK GE Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGE 3609 Score = 41.1 bits (92), Expect = 0.021 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V GK+T C ++G P P TWF D +++ I + +L I + D G Sbjct: 5978 VVGGKIT-LTCLISGNPVPTATWFRGDEELKSGGRIHIETTDD-RSSLTIERIQFRDEGE 6035 Query: 463 VTCVARNKSGETAFQCRLNV 482 V +N GE + +L V Sbjct: 6036 YELVVKNDGGEDSCVVKLTV 6055 Score = 40.7 bits (91), Expect = 0.028 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVA 1769 P FT MK + E Q F+ + G PK V W + I R + +V Sbjct: 104 PSFTSKMKPVDAEEGQEVRFDVHV--KGSPKPDVVWYKGSTMIGTHERFQIVEAAEDHVT 161 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 L + V ED+ TY A N++G+ + + L V+ + Sbjct: 162 LVISEVKLEDAETYKVVATNDVGKVTSRADLRVKER 197 Score = 40.7 bits (91), Expect = 0.028 Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 5/129 (3%) Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAV--NQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872 ++AL K + + R DV+V AP F L + EG+ + C++ P Sbjct: 268 DTALYKCEAENKLGKASRAFDVKVKAPKGDAPSFTIDLTH-VRAIEGEESKLVCKVTGKP 326 Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932 P +EW + + R RT + A L I D+G Y A N+ G A S Sbjct: 327 APT--IEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIA 384 Query: 1933 RLNVQSKES 1941 L VQ + + Sbjct: 385 ELQVQERST 393 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 5/110 (4%) Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737 T H E+ ++ E+ P ++D +P G V F R+ G P +++W Sbjct: 379 TAHSIAELQVQ-ERSTKPEIEDSLRDVSALP-GERVKFKVRIG--GKPKPKVEWRKGKSV 434 Query: 3738 FATGSRVHTLNDFGFI-ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786 G R + + +L I + DAG Y C ATN+ G A + A++T Sbjct: 435 IEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLT 484 Score = 40.7 bits (91), Expect = 0.028 Identities = 36/156 (23%), Positives = 68/156 (43%), Gaps = 12/156 (7%) Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITVM---QAPQF--SRALHNIETVEGTNVH 1329 I+ T + A+ + +A + T R D+TV+ Q P F I EG +++ Sbjct: 1825 ILNTTMEDAAMYKCVAFNEAGKTT--CRADLTVIEKQQPPTFLGDDGTQTIIVKEGDDLN 1882 Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN 1389 + + G + V W+ +G+ + + D L + + ED+G Y C+A N Sbjct: 1883 ISATI--AGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAGSYKCEANN 1940 Query: 1390 QLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425 +LG + ++V++ E Q PS ++ +E Sbjct: 1941 KLGTVTKTYNVKVMSTAP---EGQAPSFTSEMSQVE 1973 Score = 40.7 bits (91), Expect = 0.028 Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 4/113 (3%) Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 I Q S RP F + ++++ E + G + FE Q+ P V ++++ I R + Sbjct: 2052 IVTQRSIRPIFGQKMKNV-EGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSI 2108 Query: 822 IFNF-GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLG 873 + G L I + R EDAG Y AVN GE S + V T+ +G Sbjct: 2109 VEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTIPQFIG 2161 Score = 40.7 bits (91), Expect = 0.028 Identities = 18/53 (33%), Positives = 27/53 (50%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163 P + V EGE + CRV+G P+P + WL +G + +R K +DG Sbjct: 2551 PTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTYFDG 2603 Score = 40.7 bits (91), Expect = 0.028 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 3/116 (2%) Query: 637 PQFI-VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 P FI + + +TA EG I ++ G P +E+LK+ + S R + Sbjct: 2744 PSFIGIEFEPITAYEGSDIDLTFYVK--GRPLPTVEFLKDEVPVFKSDRTELTSNGNRHT 2801 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751 L + L ++DS Y A + GVA L V P+ ++ PE +Q ++ E Sbjct: 2802 LYLSDLAVRDSATYKAVAKNKAGVARRSVELLVKPKRGLKPGEAAPEIVQRLKACE 2857 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 2/94 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+ + LK+ EG F+ R G PT IEW K+ ++ + R L Sbjct: 2847 PEIVQRLKACEVPEGSS--FKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFL 2904 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTP 730 + L +D G Y A + G T A L + P Sbjct: 2905 NFLETEARDEGRYMLVAKNHLGSVSTSAELIIEP 2938 Score = 40.7 bits (91), Expect = 0.028 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 4/97 (4%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV- 828 P+F L+++ ++ EG A F ++ +P +VEW+K G+ I + +R +S + Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 +L I + ED G+Y A N G+ + + V R Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329 Score = 40.7 bits (91), Expect = 0.028 Identities = 38/150 (25%), Positives = 58/150 (38%), Gaps = 14/150 (9%) Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 L I +ED + A N G+ C+A L+V+ + + P S V Sbjct: 5930 LCISCATIEDEGEYTCRASNPAGSCSCTAELIVDAPAKVDQAA-TPGS--------GVVG 5980 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 G++ L ++G W + ++++ R I D +L I +D G+YE V Sbjct: 5981 GKIT-LTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELV 6039 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTK 4617 N GE CVV L D Q K Sbjct: 6040 VKNDGGE----DSCVVKLTVDDDSGDMQMK 6065 Score = 40.3 bits (90), Expect = 0.037 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 2/83 (2%) Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762 + +DV E C + G PT +W+ + R+ + G L I A Sbjct: 16 EGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTRA 73 Query: 3763 RDAGEYTCRATNKWGSATTTAKI 3785 D GEY C N+ G+AT+ A + Sbjct: 74 EDQGEYKCVLRNEHGTATSKAPL 96 Score = 40.3 bits (90), Expect = 0.037 Identities = 35/141 (24%), Positives = 58/141 (41%), Gaps = 5/141 (3%) Query: 1264 SAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETV 1323 S +V + I +Q + L + T + ++ V P F+ + ++ Sbjct: 57 SEVVNGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVPVKPSFTSKMKPVDAE 116 Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYVALDLLSVYPEDSG 1381 EG V + ++ G V W+ I T RF+ A E D+V L + V ED+ Sbjct: 117 EGQEVRFDVHVK--GSPKPDVVWYKGSTMIGTHERFQIVEAAE-DHVTLVISEVKLEDAE 173 Query: 1382 VYTCQATNQLGEAVTSCALRV 1402 Y ATN +G+ + LRV Sbjct: 174 TYKVVATNDVGKVTSRADLRV 194 Score = 40.3 bits (90), Expect = 0.037 Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 4/100 (4%) Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823 ++ S +P+ L+D+ L G F+ ++ P +VEW K I R T Sbjct: 389 QERSTKPEIEDSLRDVSALP-GERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAE 445 Query: 824 NFGYV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 V SL I L DAG Y A N+ GEA S A + V Sbjct: 446 ESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485 Score = 40.3 bits (90), Expect = 0.037 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV-TLSINSLRNDDSGIY 2715 G+ V + ++ + P K+EW K + G R + V +L I L D+G Y Sbjct: 409 GERVKFKVRIGGKPKP--KVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRY 466 Query: 2716 TCKATNLLGEAVSTASIKIED 2736 C ATN GEA S A + + + Sbjct: 467 KCVATNEAGEAESMAQLTVNE 487 Score = 40.3 bits (90), Expect = 0.037 Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 2/56 (3%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 G P ++EWF+ ++ + SSRI K+ D + +MT+S + +D G+Y C A N G Sbjct: 1594 GKPQPELEWFKYDRTLWKSSRINFKSRDNKF-TMTVSDLGLDDSGMYQCVARNKAG 1648 Score = 40.3 bits (90), Expect = 0.037 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 4/112 (3%) Query: 2914 IIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDL 2973 II ++ EG + LE V K P+ IEWY +G R T D ++ Sbjct: 1670 IITHLISKEVKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMTTFDGSVASVTF 1727 Query: 2974 VDVYERDSGIYTCKAYNKRGEAFTSS--TVYCTSKDNLIERTQHPKGTEGLE 3023 D D G Y C A N G A +S+ TV SK ++ + + EG E Sbjct: 1728 TDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSKPEFKQKLRPLEVVEGSE 1779 Score = 40.3 bits (90), Expect = 0.037 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPS-GHRYRTVYD 3883 V + P+F +++ V E +F+ R+ K PK +EWYR K+ S H+ Y+ Sbjct: 1759 VPSKPEFKQKLRPLEVVEGSEAKFDVRI--KSYPKPEVEWYRGTTKITDSLRHQITEPYE 1816 Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920 SL IL ED+ Y C A N+ G+ +A ++ Sbjct: 1817 GDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLT 1854 Score = 40.3 bits (90), Expect = 0.037 Identities = 37/145 (25%), Positives = 59/145 (40%), Gaps = 13/145 (8%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 P+ E P + ++Q V +EG++ E R+ +P + W +G +R +T+ D Sbjct: 2546 PTGEEPTILQRLQPVDT-IEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFD 2602 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK 3396 + L I + G Y C A N G + A L +E PR LEK Sbjct: 2603 GDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLERE------ARPR----ILEK 2652 Query: 3397 LQTLEDSMVRRKDTSVEEEKGKAPV 3421 LQ ++ S+ R + PV Sbjct: 2653 LQDVDSSVGERAMFKIRVSGSPMPV 2677 Score = 40.3 bits (90), Expect = 0.037 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 4/91 (4%) Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR-IQTYHDFGY 1100 +PR L L+ + V G+ A F+ RV V+WY ++IT+ I GY Sbjct: 2646 RPRILEKLQDVDSSV-GERAMFKIRVSGSP--MPVVQWYRRDEEITTKGHYIVRDEGRGY 2702 Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSA 1131 +L I + ED G Y V N +GE +A Sbjct: 2703 FSLTIEYIDYEDEGAYKAVVINDSGEVSSTA 2733 Score = 40.3 bits (90), Expect = 0.037 Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYV 1775 ++D+ + + A F+ R+ G P V+W R I + GY +L ++Y+ Sbjct: 2653 LQDVDSSVGERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLTIEYI 2710 Query: 1776 NPEDSGTYTCRAINELGEAVTSSTL 1800 + ED G Y IN+ GE +++ L Sbjct: 2711 DYEDEGAYKAVVINDSGEVSSTAVL 2735 Score = 40.3 bits (90), Expect = 0.037 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 3/99 (3%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP + +L ++ EG S CR+ P P +EWY + L+ R + Sbjct: 2846 APEIVQRLKA-CEVPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQY 2902 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 L+ L D G Y A N+LG +S L ++ S Sbjct: 2903 FLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVS 2941 Score = 40.3 bits (90), Expect = 0.037 Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 2/77 (2%) Query: 3710 GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYT 3769 GG + C + G+P WF +G R+H +L I+ I RD GEY Sbjct: 5980 GGKITLTCLIS--GNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYE 6037 Query: 3770 CRATNKWGSATTTAKIT 3786 N G + K+T Sbjct: 6038 LVVKNDGGEDSCVVKLT 6054 Score = 39.9 bits (89), Expect = 0.049 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 2/102 (1%) Query: 3551 EAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN 3610 +A G+ P FT + + E + C++ + +EW P+ T RV+T Sbjct: 292 KAPKGDAPSFTIDLTHVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDF 349 Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 + L I DAG Y A N G A +LQV+ R Sbjct: 350 EKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQER 391 Score = 39.9 bits (89), Expect = 0.049 Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 2/109 (1%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P F + E S R+ + +EW +GK + + V T +L Sbjct: 492 PRFEKMKESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVL 549 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666 I + D+GLY C A N+ G A ++ +L V+ ++ P++ S + Sbjct: 550 TIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELR 598 Score = 39.9 bits (89), Expect = 0.049 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 6/112 (5%) Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223 E +++ I+ ++P F L P EG+ + L+ ++E G P +EW+ + Sbjct: 673 ESKTKLKVIAFARPEFRTKLK-PVKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVES 729 Query: 1224 SRFKTY---YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 RFK + G +L I DTG V A N G A + A + V ER Sbjct: 730 GRFKVMEEEEEDGLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKER 781 Score = 39.9 bits (89), Expect = 0.049 Identities = 20/64 (31%), Positives = 29/64 (45%) Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371 P +EW+ +G + R T D + + + GEY+CVATN LG + A Sbjct: 1695 PAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSAR 1754 Query: 3372 LKCT 3375 L T Sbjct: 1755 LTVT 1758 Score = 39.9 bits (89), Expect = 0.049 Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 3/95 (3%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYV 2035 +P FG+ +KN E G V E + P V ++ + G R+ + G Sbjct: 2059 RPIFGQKMKNVEGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSIVEEENGLF 2116 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 L I ED G Y C A N GE + + V+ Sbjct: 2117 VLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVE 2151 Score = 39.9 bits (89), Expect = 0.049 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 4/96 (4%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GLV 2700 PIF +K+ + + G+ V E QVE P + + + + G R + GL Sbjct: 2060 PIFGQKMKNVEGRI-GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLF 2116 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 L+I + R +D+G Y C A N GE S + +E+ Sbjct: 2117 VLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEE 2152 Score = 39.9 bits (89), Expect = 0.049 Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 7/125 (5%) Query: 1820 KIQQLEDSSRYQRREDVEVAVNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNM 1876 K L +S + R E+ VN+ P F +G +L EG + + ++ P P + Sbjct: 3015 KCTALNESGKSSTR--AELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVKGNPYPEI 3072 Query: 1877 RVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 R WY + + + S +L + V +DSG Y C N +G A S ++V Sbjct: 3073 R--WYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDV 3130 Query: 1937 QSKES 1941 ++K+S Sbjct: 3131 EAKKS 3135 Score = 39.9 bits (89), Expect = 0.049 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 2/75 (2%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFD 4168 P F+ + + EG AR C RV G P+P + W + I G R + + DG+ Sbjct: 3735 PSFLQRMQDLEIVEGSAARLCVRVQGVPEPEIDWYKDNRVIREGGRVEFEFEEDGLCMLV 3794 Query: 4169 IPKTRQYDTGKIEVI 4183 I + D G+ + + Sbjct: 3795 IRDATKSDRGRYKCV 3809 Score = 39.9 bits (89), Expect = 0.049 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 2/80 (2%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G + +F + P P V+W + PL +Y + G SL IK D G Y Sbjct: 4114 EGMSVRFNCRTTSQPKPYVTWFKDGQPLASYGRYEV--TSVAGAQSLTIKDCKLADAGIY 4171 Query: 145 TCTARNQYGEAICSVYIQPE 164 C N G+A S ++ E Sbjct: 4172 KCEVSNVGGKAGTSAHLTVE 4191 Score = 39.5 bits (88), Expect = 0.065 Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+ PL+SV EG E + G P+ +EW K+ + S R L Sbjct: 1094 PKITKPLESVEVNEGEDFDLECVVS--GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKL 1151 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 +D GEY C ++ G A T + V Sbjct: 1152 VFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183 Score = 39.5 bits (88), Expect = 0.065 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAG 3628 + E S+A+ C++ ++W +G + SR+K + D L I D G Sbjct: 1384 IDEGSTANLVCKVTAAKPEPS-IKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEG 1442 Query: 3629 LYTCKATNRHGEATVSCKLQV 3649 +Y TN +G A+ +C++ V Sbjct: 1443 VYKVTLTNEYGTASSTCRVLV 1463 Score = 39.5 bits (88), Expect = 0.065 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 8/112 (7%) Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288 S R+ V P S P F +LR V EG A F+ +++ P +E+Y + + Sbjct: 1752 SARLTVTVP--SKPEFKQKLR-PLEVVEGSEAKFDVRIKSYPKPE--VEWYRGTTKITDS 1806 Query: 2289 ARFHITFDF---GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 R IT + SL I + EDA Y A N G T +TV K Sbjct: 1807 LRHQITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK 1858 Score = 39.5 bits (88), Expect = 0.065 Identities = 20/89 (22%), Positives = 45/89 (50%), Gaps = 4/89 (4%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFGLVTLSINSLRND 2710 ++ EG E +V+ P ++EW+ + R ++S + G +L++ + + Sbjct: 2362 EVTEGDRAKFEVRVKGYPYP--EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQE 2419 Query: 2711 DSGIYTCKATNLLGEAVSTASIKIEDRHW 2739 D+G+Y C A N G++ A +++ +R + Sbjct: 2420 DAGMYKCIAVNKAGKSTCRADLEVNERQF 2448 Score = 39.5 bits (88), Expect = 0.065 Identities = 47/231 (20%), Positives = 81/231 (35%), Gaps = 20/231 (8%) Query: 3983 TSLVEMET-TKFECQLAPVGDPNM--KVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVY 4039 T L ME + + L + P K+EWF + + + + RFT + + Sbjct: 4888 TPLANMEVFSGDDVMLEVISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATAT 4947 Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPE 4099 +D G + C N +G+ A I +S + +I + + Sbjct: 4948 FDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIERRRSRDSICAL 5007 Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 + +E K R V +G+ F R+TG P+P+V+W + +V R Sbjct: 5008 EFQQELKDR------------EVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIF 5055 Query: 4160 TYD---GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV--IPRHDD 4205 + G+Y I K D G + L V +P +D Sbjct: 5056 VSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEED 5106 Score = 39.5 bits (88), Expect = 0.065 Identities = 37/131 (28%), Positives = 49/131 (37%), Gaps = 5/131 (3%) Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739 L IS A EDEG+Y C A N AG + A+L V P + D A TP +V G Sbjct: 5930 LCISCATIEDEGEYTCRASNPAGSCSCTAELIVDAPAKVDQ--AATPGSGVV---GGKIT 5984 Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799 I+ PT W R + + + + L I D G + Sbjct: 5985 LTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVKNDG 6044 Query: 4800 GQVETSAKLVV 4810 G+ KL V Sbjct: 6045 GEDSCVVKLTV 6055 Score = 39.1 bits (87), Expect = 0.086 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 9/117 (7%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 ++W +DG + +SRI F+ +LTI+ T+ D G Y N G A+++ + + Sbjct: 1405 IKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLV- 1463 Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPR-FLGPLKGTNKIVEG 1058 ++ + L+ + +E S T EVK++ PR + K +++I +G Sbjct: 1464 --NEVGSRPIFQQKLKAVSTIEGES-----TRFEVKLSAMPRPTVEWFKSSSQIYDG 1513 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 2/83 (2%) Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567 P F GP E EG RV G P EW+ L SR T Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFKSRDNKFT 1625 Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590 + ++ + +D+G+Y C A N+AG Sbjct: 1626 MTVSDLGLDDSGMYQCVARNKAG 1648 Score = 39.1 bits (87), Expect = 0.086 Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 12/112 (10%) Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT--IGHRF-RP 1495 +V KP F + + +E V+EG F+ +++ +VEW++ +T + H+ P Sbjct: 1758 TVPSKPEFKQKLRPLE-VVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITEP 1814 Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547 +L I++ ED+ +Y C A N G + TCR+ ++ Q Sbjct: 1815 YEGDDTYSLIILNTTMEDAAMYKCVAFNEAG------KTTCRADLTVIEKQQ 1860 Score = 39.1 bits (87), Expect = 0.086 Identities = 36/127 (28%), Positives = 54/127 (42%), Gaps = 4/127 (3%) Query: 1012 QHPGGLEKIQYLEDASRYSKRTEEEVKITQ-KPRF-LGPLKGTNKIVEGQSAHFEARVEP 1069 Q G+ K + A + + R + EV Q P F G +G + EG +V Sbjct: 2418 QEDAGMYKCIAVNKAGKSTCRADLEVNERQFAPEFETGEERGPIVVPEGGETTL--KVTL 2475 Query: 1070 QSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL 1129 +++ V WY +GK + R+ L I + + EDSG Y ARN G A Sbjct: 2476 RANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADK 2535 Query: 1130 SASMTVE 1136 S ++ VE Sbjct: 2536 SFTIRVE 2542 Score = 39.1 bits (87), Expect = 0.086 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 5/105 (4%) Query: 3680 HKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA 3739 H E+T+ + + P R +++D +D G F RV G P + W+ Sbjct: 2633 HSSAELTVLEREARP-RILEKLQD-VDSSVGERAMFKIRVS--GSPMPVVQWYRRDEEIT 2688 Query: 3740 T-GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTA 3783 T G + G+ +L I+YI D G Y N G ++TA Sbjct: 2689 TKGHYIVRDEGRGYFSLTIEYIDYEDEGAYKAVVINDSGEVSSTA 2733 Score = 39.1 bits (87), Expect = 0.086 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 PE +K + EG + F+ R G T +EW K P++ + R+ Sbjct: 2847 PEIVQRLK-ACEVPEG--SSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 L D G Y A N +G +TSA L I Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAELII 2936 Score = 39.1 bits (87), Expect = 0.086 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P Q L+ + + EG + CR+ G PT +EW+++ ++ + R+ H Sbjct: 2847 PEIVQRLKACE-VPEGSSFKLRCRV--TGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 + DEG YM A N LG Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLG 2926 Score = 39.1 bits (87), Expect = 0.086 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P F P ELQEG +A + +P + WYKD S ++ S Sbjct: 3040 PGFEGPDHGSYELQEGDTITLDAVVK--GNPYPEIRWYKDEFLAMESKKLMLSVRDRKNS 3097 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARST 867 L + H+ +D+G Y NK+G A + ++ V A+ + Sbjct: 3098 LTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKS 3135 Score = 39.1 bits (87), Expect = 0.086 Identities = 18/63 (28%), Positives = 33/63 (52%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 ++WY + ++ + + ++ +L IM +PED+G C A+N G A S ++ Sbjct: 3366 LQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIE 3425 Query: 1671 SKK 1673 SKK Sbjct: 3426 SKK 3428 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 4/83 (4%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD-VS 130 P+F + +G + E ++R P P+V W + E Y + Y E G + Sbjct: 3431 PLFIAPLHDQEVVEGETIRLECRVRATPRPMVEWKKDGRTFKE--DYHI-YTEFDGQHCT 3487 Query: 131 LLIKQIGPGDEGEYTCTARNQYG 153 L+IK DEG Y C A+N+ G Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEG 3510 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 2/89 (2%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 +FI+ L++ EG+ I EC V + P +EW + + + D + +L Sbjct: 3432 LFIAPLHDQEVVEGETIRLECRVRATPRPM--VEWKKDGRTFKEDYHIYTEFDGQHCTLV 3489 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 I ED G Y C A N +G + L Sbjct: 3490 IKGAQIEDEGAYECIAKNKEGRGRSVAQL 3518 Score = 38.7 bits (86), Expect = 0.11 Identities = 20/88 (22%), Positives = 37/88 (42%), Gaps = 1/88 (1%) Query: 1447 VTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDI 1506 + R + + EG + CK+ ++W ++G + R + + D +L I Sbjct: 1375 IIRKLQAQEIDEGSTANLVCKVTAAKPEP-SIKWTRDGVKIRENSRIKMVFDGETCSLTI 1433 Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 D +D G+Y N GT +CR+ Sbjct: 1434 RDATLDDEGVYKVTLTNEYGTASSTCRV 1461 Score = 38.7 bits (86), Expect = 0.11 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 5/102 (4%) Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF- 1765 + P F ++ + V E A F+ R+ PK VEW R I S R + Sbjct: 1759 VPSKPEFKQKLRPLEVVEGSEAKFDVRIKSY--PKPEVEWYRGTTKITDSLRHQITEPYE 1816 Query: 1766 GYVALNMKYVNP--EDSGTYTCRAINELGEAVTSSTLFVQSK 1805 G ++ +N ED+ Y C A NE G+ + L V K Sbjct: 1817 GDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK 1858 Score = 38.7 bits (86), Expect = 0.11 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 5/95 (5%) Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH--KN 4020 DL ++K+QPP F+ +QT +V+ E G P+ +V W+ +G+ +L K Sbjct: 1852 DLTVIEKQQPPTFLGDDGTQTIIVK-EGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQ 1910 Query: 4021 RFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055 D ++ + F ED+G Y C A N G Sbjct: 1911 ETRKRGDESHLVV-FN-AKMEDAGSYKCEANNKLG 1943 Score = 38.7 bits (86), Expect = 0.11 Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 11/163 (6%) Query: 4087 IREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL 4146 I+ S T + +V + R P+F V GE RF +V G P P V + Sbjct: 2038 IQNQHGSTTTTVQVIVTQRSIR--PIFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHR 2095 Query: 4147 NGNTIVNGSRYKLTYD--GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV----- 4199 I +G RY + + G++ I TR D G+ + I L V Sbjct: 2096 ESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELT 2155 Query: 4200 IPRH-DDYRGVLKNAPRPWYDETTQYQRT-ETELEKTFEERQV 4240 IP+ D GV++ YD + + + T E+E ER + Sbjct: 2156 IPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLI 2198 Score = 38.7 bits (86), Expect = 0.11 Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 6/108 (5%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E I E + P F L + E+ EG F+ +L +PT VEWYK+ + I Sbjct: 2933 ELIIEPSVSPPSFRHRLTAV-EVDEGDETRFDVRLK--KEPTS-VEWYKEQQRIFTDGHF 2988 Query: 820 TSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 I SL I + + DAG Y A+N+ G++ + A + V R Sbjct: 2989 EVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036 Score = 38.7 bits (86), Expect = 0.11 Identities = 46/165 (27%), Positives = 68/165 (41%), Gaps = 19/165 (11%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC--DFGF 3477 P F L+ +E + EG+ F+ RL +P VEWY + + F + Sbjct: 2943 PSFRHRLTAVE-VDEGDETRFDVRLKK--EPT-SVEWYKEQQRIFTDGHFEVIEGEEECL 2998 Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537 L IS T D+G Y C A N G++ T A + ++ E +P G EG + Sbjct: 2999 YSLVISNTKVADAGGYKCTALNESGKSSTRAEL-------LVNERLIPPGFEG--PDHGS 3049 Query: 3538 LEGYSGTVDTLTPEA-ESGNP-PEFTTTPSDLILSENSSAHFECR 3580 E G DT+T +A GNP PE + + E+ R Sbjct: 3050 YELQEG--DTITLDAVVKGNPYPEIRWYKDEFLAMESKKLMLSVR 3092 Score = 38.7 bits (86), Expect = 0.11 Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSD--FGFVTLDLVDVYERDSGIYTCKAYNKR 2992 VE P K+EW + L G R L D L + + DSG YTC A NK Sbjct: 3548 VEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSGKYTCIARNKA 3607 Query: 2993 GE 2994 GE Sbjct: 3608 GE 3609 Score = 38.7 bits (86), Expect = 0.11 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%) Query: 86 GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145 GG + GNP P +W R L + + + SL I++I DEGEY Sbjct: 5980 GGKITLTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRS--SLTIERIQFRDEGEYE 6037 Query: 146 CTARNQYGEAICSV 159 +N GE C V Sbjct: 6038 LVVKNDGGEDSCVV 6051 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 3/95 (3%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 KP+ +++ G V + + P +VEW ++ G RF + V Sbjct: 394 KPEIEDSLRDVSALPGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEVF 451 Query: 2037 LDILYAYAE-DTGTYMCKATNAVGEAVTTSSVKVD 2070 I+ E D G Y C ATN GEA + + + V+ Sbjct: 452 SLIIQDLEETDAGRYKCVATNEAGEAESMAQLTVN 486 Score = 38.3 bits (85), Expect = 0.15 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 3/85 (3%) Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SLDITHT 2838 L ++ G+ + F+ + P K+EW + G R+ + V SL I Sbjct: 401 LRDVSALPGERVKFKVRIGGKPKP--KVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDL 458 Query: 2839 YEEDSGIYTCKATNSKGSATTSGSL 2863 E D+G Y C ATN G A + L Sbjct: 459 EETDAGRYKCVATNEAGEAESMAQL 483 Score = 38.3 bits (85), Expect = 0.15 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%) Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982 +VEG+ + L +V K P+ IEW +GK + + + L + + DSG Sbjct: 503 VVEGESVELVARVTGKPAPE--IEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSG 560 Query: 2983 IYTCKAYNKRGEA 2995 +Y C A NK G A Sbjct: 561 LYRCTARNKSGTA 573 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 2/101 (1%) Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843 EG + A++T P +EW KDG+ + ++ + + L I +D+G Y Sbjct: 505 EGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLY 562 Query: 844 TVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKT 884 A NK G A T + V + I + R +E T Sbjct: 563 RCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEAT 603 Score = 38.3 bits (85), Expect = 0.15 Identities = 50/207 (24%), Positives = 84/207 (40%), Gaps = 43/207 (20%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFGYVSMTISHVRDED 2445 + EG R+ +P V+WF++ + I +S++ I + + +++ +S + ED Sbjct: 797 VTEGNEVSIQLRV--KANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSL--ED 852 Query: 2446 EGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREF 2505 GVY C ASN LG+ ++++ + P+G Sbjct: 853 TGVYKCEASNRLGK--------ASRSFDVKVQVKGPKG---------------------- 882 Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS--RFRTTHDF 2563 E PI L P E EG+ + + G P+ EW +G+ ++ + TT D Sbjct: 883 EAPIILSKLR-PVETEEGEET--KLKCTFTGKPAPTCEWTRDGIRIRSSRMVQIDTTEDS 939 Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590 TL I +D GLY C N G Sbjct: 940 S--TLIIKETTLDDEGLYKCTIKNDLG 964 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 2/94 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 +AP L +ET EG L+C G EW +G I++ + D Sbjct: 883 EAPIILSKLRPVETEEGEETKLKCTF--TGKPAPTCEWTRDGIRIRSSRMVQIDTTEDSS 940 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + +D G+Y C N LG TS + V Sbjct: 941 TLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLV 974 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 3/105 (2%) Query: 631 DRVYPPPQFIVPLKS-VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689 + V P+F+ + + EG + R+ G P ++EW K +++ SSR Sbjct: 1562 NEVLTVPEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFKS 1619 Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734 R ++ + L + DSG Y C A + G + L V + I Sbjct: 1620 RDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664 Score = 38.3 bits (85), Expect = 0.15 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 3/90 (3%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR-PAYEFDY 1367 QAP F+ + +E EG V L + T V+W +G P+ +R + Sbjct: 1961 QAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPT--VKWTRDGIPVFEDYRISMDSSRVQG 2018 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397 V L + +V D GVY C NQ G T+ Sbjct: 2019 VTLIIRNVTRYDEGVYKCTIQNQHGSTTTT 2048 Score = 38.3 bits (85), Expect = 0.15 Identities = 22/100 (22%), Positives = 39/100 (39%), Gaps = 2/100 (2%) Query: 3550 PEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI 3609 P+ G P + + + E A E + + +EW+ +G + RV++ Sbjct: 2249 PKRPEGTEPNIVSGLKSVEVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVRST 2306 Query: 3610 NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 + G L I + D G Y C+ N G + S L + Sbjct: 2307 LENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346 Score = 38.3 bits (85), Expect = 0.15 Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 6/105 (5%) Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030 + P + ++Q +E E K EC+++ G P + W +G L NR +D Sbjct: 2549 EEPTILQRLQP-VDTIEGEAIKMECRVS--GKPEPTITWLKDGLVFLTDNRIKTYFDGDV 2605 Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGIV 4072 + V D G Y C A N G + A V++ +P I+ Sbjct: 2606 CTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLEREARPRIL 2650 Score = 38.3 bits (85), Expect = 0.15 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 13/118 (11%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGH-RYRTF 3334 PS PP F ++ V ++ EG F+ RL +P VEW+ +++ GH Sbjct: 2938 PSVSPPSFRHRLTAV-EVDEGDETRFDVRLKK--EPT-SVEWYKEQQRIFTDGHFEVIEG 2993 Query: 3335 HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392 + + L I ++G Y+C A N+ G+ ST+A L L+ + +P G EG Sbjct: 2994 EEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL-------LVNERLIPPGFEG 3044 Score = 38.3 bits (85), Expect = 0.15 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 3/118 (2%) Query: 3534 KIAALEGYSGTVDTLTPEAESGNP-PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592 K A+ + T ES P P F D + E + ECR + M VE Sbjct: 3406 KCVAMNPAGSASKSFTVVIESKKPAPLFIAPLHDQEVVEGETIRLECR-VRATPRPM-VE 3463 Query: 3593 WFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 W +G+ + T D L I G D G Y C A N+ G +L VK Sbjct: 3464 WKKDGRTFKEDYHIYTEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK 3521 Score = 37.9 bits (84), Expect = 0.20 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 11/127 (8%) Query: 3391 EGGLEKLQTLEDSMVRRKDTSVE-EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449 + G K+ DS ++ +E+ P L ++ L GE F+ R+ Sbjct: 365 DAGTYKVVARNDSGTAHSIAELQVQERSTKPEIEDSLRDVSAL-PGERVKFKVRIGGKPK 423 Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCD----FGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505 P KVEW ++ G RF + F +I ++ T D+G Y C A N GEA Sbjct: 424 P--KVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEET---DAGRYKCVATNEAGEAE 478 Query: 3506 TTASMKV 3512 + A + V Sbjct: 479 SMAQLTV 485 Score = 37.9 bits (84), Expect = 0.20 Identities = 31/124 (25%), Positives = 48/124 (38%), Gaps = 6/124 (4%) Query: 3976 VTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNF 4035 +T+ + E E EC ++ G P+ VEW + L R D + F Sbjct: 1096 ITKPLESVEVNEGEDFDLECVVS--GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVF 1153 Query: 4036 GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQ 4095 PED GEY C N +G T +K ++ + M +E EA+++ Sbjct: 1154 KQARPEDIGEYKCTVINEHGKASTTGEVKV----NVLSRPEFKIKMSPVEVTEGSEAAFE 1209 Query: 4096 VTPE 4099 V E Sbjct: 1210 VRVE 1213 Score = 37.9 bits (84), Expect = 0.20 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 3/89 (3%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P F ++ S + E FE ++ G P ++VEWF + R+T D Sbjct: 1189 PEFKIKM-SPVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRYT 1245 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKA 4061 M V ED+G Y C ATN G ++A Sbjct: 1246 MVIANVTLEDAGGYRCVATNTAGKTTSRA 1274 Score = 37.9 bits (84), Expect = 0.20 Identities = 27/102 (26%), Positives = 40/102 (39%), Gaps = 5/102 (4%) Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF- 2032 V KP+F + ++ EV EG + + P VEWY + R + T + Sbjct: 1759 VPSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITEPYE 1816 Query: 2033 --GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 +L IL ED Y C A N G+ + + V K Sbjct: 1817 GDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK 1858 Score = 37.9 bits (84), Expect = 0.20 Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 3/99 (3%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD-FGY 2034 + P F + EV EG V L ++ PT V+W +G PV + +R Sbjct: 1961 QAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPT--VKWTRDGIPVFEDYRISMDSSRVQG 2018 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 V L I D G Y C N G TT V V +S Sbjct: 2019 VTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS 2057 Score = 37.9 bits (84), Expect = 0.20 Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 3/96 (3%) Query: 1978 PQFGKPIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 PQF + E+ +G + + +L P +EWY N R + R + ++ Sbjct: 2157 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 + + +D+G Y CKA N G ++ V K Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK 2250 Score = 37.9 bits (84), Expect = 0.20 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 R ++ + + + P T E + I VPEGG +V +P ++ W+ +G+ + Sbjct: 2438 RADLEVNERQFAPEFETGEERGPIVVPEGGETTL--KVTLRANPKPQVIWYKDGKHTSEN 2495 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779 R+ + L I D+G Y C A NK G A Sbjct: 2496 IRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFA 2533 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 5/106 (4%) Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705 + EGG+ + + +P ++ W K+G+ + R R L + + I+D Sbjct: 2461 IVVPEGGETTLKVTLR--ANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIED 2518 Query: 706 SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751 SG Y C A + G A+ + V + T + P LQ +Q ++ Sbjct: 2519 SGSYKCEARNKLGFADKSFTIRV---EVPKPTGEEPTILQRLQPVD 2561 Score = 37.9 bits (84), Expect = 0.20 Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 14/139 (10%) Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 +V + +P ++ WY +GK + R + S L + + DSG Y C+A NK G Sbjct: 2472 KVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLG 2531 Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGT-EGLEKIQNLE--DSLRKEPGQQPDDDTGRPPEF 3050 A S T+ R + PK T E +Q L+ D++ E + +G+P Sbjct: 2532 FADKSFTI----------RVEVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT 2581 Query: 3051 TTVFKD-IVDISEGQIAHY 3068 T KD +V +++ +I Y Sbjct: 2582 ITWLKDGLVFLTDNRIKTY 2600 Score = 37.9 bits (84), Expect = 0.20 Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 14/124 (11%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 E+ IE +PP F + ++V EG FD R++ +PT ++W+ + T Sbjct: 2933 ELIIEPSV-SPPSFRHRLTA-VEVDEGDETRFDVRLKK--EPTS-VEWYKEQQRIFTDGH 2987 Query: 3744 VHTLN--DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801 + + +L I DAG Y C A N+ G ++T A++ +V E +P Sbjct: 2988 FEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL-------LVNERLIPP 3040 Query: 3802 GMSG 3805 G G Sbjct: 3041 GFEG 3044 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 4/101 (3%) Query: 1987 AEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAED 2046 A + EG + L ++T +P ++WY +G +++ + +L I+ ED Sbjct: 3344 ALLNEGDDLRLVVSVT--GNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPED 3401 Query: 2047 TGTYMCKATNAVGEAVTTSSVKVDAK--SGLYLDTLDEQRL 2085 TG C A N G A + +V +++K + L++ L +Q + Sbjct: 3402 TGVIKCVAMNPAGSASKSFTVVIESKKPAPLFIAPLHDQEV 3442 Score = 37.9 bits (84), Expect = 0.20 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Query: 4122 VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD---GMYHFDIPKTRQYDTG 4178 V EG+ A+F V+G P +V WL + NG R L D MY I + D+G Sbjct: 3538 VIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSG 3597 Query: 4179 KIEVI 4183 K I Sbjct: 3598 KYTCI 3602 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 2/101 (1%) Query: 62 TAGRPGEP-SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120 T G P E +PP F + +N +GG KF ++ V W K L+ + Sbjct: 3865 TEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVISKAPIKVEW-YKDDRLISSDWPRH 3923 Query: 121 RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161 + ++ I + D G YT N+YG Y+ Sbjct: 3924 TFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESKAYL 3964 Score = 37.5 bits (83), Expect = 0.26 Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 3/146 (2%) Query: 1019 KIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTV 1077 K+ D + + R + VK Q P F+ +G G V + ++T Sbjct: 176 KVVATNDVGKVTSRADLRVKERQFAPEFIDEERGPIDATTGDEVTLTCSVSGKPKPSIT- 234 Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137 WY NGK +T + ++ + + S + ED+ +Y A N G+A + + V+ Sbjct: 235 -WYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFDVKVKA 293 Query: 1138 RSSIDTSSIHRGLYEKTRHIEESKFV 1163 S + + EESK V Sbjct: 294 PKGDAPSFTIDLTHVRAIEGEESKLV 319 Score = 37.5 bits (83), Expect = 0.26 Identities = 17/56 (30%), Positives = 28/56 (50%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 G P + W++N KL+ DS ++ +T+ + ED +Y C A N LG+ Sbjct: 227 GKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGK 282 Score = 37.5 bits (83), Expect = 0.26 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +API + L+ + EG+ L+ + P EW ++G+ + + ++ Sbjct: 883 EAPIILSKLRPVET-EEGEETKLKCTFTGKPAPTC--EWTRDGIRIRSSRMVQIDTTEDS 939 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 TL I DD G+Y C N LG ++A + + + Sbjct: 940 STLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNE 976 Score = 37.5 bits (83), Expect = 0.26 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 7/144 (4%) Query: 2863 LRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGR-----RPSVPDTEYPKPEWIIPI 2917 +R GD + F + AG+ + A A + S P T +P I + Sbjct: 1320 VRAIGDSHTCFIVRAKLSDAGVYKCQATNAAGSASRSWEVKVKQSAPKTTGEEPIIIRKL 1379 Query: 2918 AAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVY 2977 A+ ++ EG +L +V P+ I+W +G + + SR K+ D +L + D Sbjct: 1380 QAQ-EIDEGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDAT 1437 Query: 2978 ERDSGIYTCKAYNKRGEAFTSSTV 3001 D G+Y N+ G A ++ V Sbjct: 1438 LDDEGVYKVTLTNEYGTASSTCRV 1461 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 2/95 (2%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 GN P+ T + E + EC + + +EW+ +G RV T D Sbjct: 1665 GNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSV 1722 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 + D G Y C ATN G A S +L V Sbjct: 1723 ASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757 Score = 37.5 bits (83), Expect = 0.26 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 3/97 (3%) Query: 2639 QQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 QQ P F + +V EG + + A + + P ++ W+K+G + + ++ Sbjct: 1859 QQPPTFLGDDGTQTIIVKEGDDLNISATIAGKPSP--EVSWYKDGRLVLDSIKQETRKRG 1916 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L + + + +D+G Y C+A N LG T ++K+ Sbjct: 1917 DESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKV 1953 Score = 37.5 bits (83), Expect = 0.26 Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 4/72 (5%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-MTISHVRDEDE 2446 ++EG + + G P+ +V W+++ +L+ DS + +T G S + + + + ED Sbjct: 1875 VKEGDDLNISATI--AGKPSPEVSWYKDGRLVLDSIK-QETRKRGDESHLVVFNAKMEDA 1931 Query: 2447 GVYMCRASNLLG 2458 G Y C A+N LG Sbjct: 1932 GSYKCEANNKLG 1943 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 4/99 (4%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDFG 2698 QAP FT+ + + + EG V L + P +K W ++G+ + R+ + Sbjct: 1961 QAPSFTSEMSQVE-VDEGGEVKLYFLISGYPKPTVK--WTRDGIPVFEDYRISMDSSRVQ 2017 Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 VTL I ++ D G+Y C N G +T + + R Sbjct: 2018 GVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQR 2056 Score = 37.5 bits (83), Expect = 0.26 Identities = 36/117 (30%), Positives = 51/117 (43%), Gaps = 9/117 (7%) Query: 1030 SKRTEEEVKITQKPRFLGPLKGTN-KIVEG---QSAHFEARVEPQSDLTMTVEWYFNGKQ 1085 S T +V +TQ R + P+ G K VEG + FE +VE V ++ +Q Sbjct: 2044 STTTTVQVIVTQ--RSIRPIFGQKMKNVEGRIGEDVRFEIQVEGTP--VPAVTFHRESEQ 2099 Query: 1086 ITSANRIQTYHDF-GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141 I R + G L I + R ED+G Y +A N AGE + VE +I Sbjct: 2100 IYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI 2156 Score = 37.5 bits (83), Expect = 0.26 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 6/102 (5%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 + S P F+ + + + EG F+ RL+ S VEW K+ + + Sbjct: 2936 IEPSVSPPSFRHRLT-AVEVDEGDETRFDVRLKKEPTS---VEWYKEQQRIFTDGHFEVI 2991 Query: 962 FNFG--YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 +L I + V DAG Y C A N G+++T A L + Sbjct: 2992 EGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLV 3033 Score = 37.5 bits (83), Expect = 0.26 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 6/102 (5%) Query: 2224 EAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGK 2283 EA H++ + + +P + P F L+ V EG A F +V+ +P ++E++ GK Sbjct: 3220 EASSHASLV-LSKPLVMP-EFKERLKNIK-VVEGDEAQFSVRVKG--EPEPKVEWFKTGK 3274 Query: 2284 ALQSAARFHITFDFGYV-SLDIQHCVPEDAGEYSVKAINALG 2324 ++S ARF + +L I ED G Y A N G Sbjct: 3275 KIKSHARFSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAG 3316 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 2/89 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F L ++ EG+ C V PT IEW P+ + R ++ + + +L I Sbjct: 301 FTIDLTHVRAIEGEESKLVCKVTGKPAPT--IEWLKGELPVTTSLRVRTDFEKNVATLVI 358 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLR 2864 T D+G Y A N G+A + L+ Sbjct: 359 KDTRLGDAGTYKVVARNDSGTAHSIAELQ 387 Score = 37.1 bits (82), Expect = 0.35 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF--- 825 RP+F L+ + + EG + ++ P +EWY+ I S R + Sbjct: 685 RPEFRTKLKPVKAV-EGEEVQLDVKVEGYPKPD--IEWYRGTTMIVESGRFKVMEEEEED 741 Query: 826 GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 G SL I L+ +D G+ V A N G+A S A + V R Sbjct: 742 GLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKER 781 Score = 37.1 bits (82), Expect = 0.35 Identities = 18/58 (31%), Positives = 27/58 (46%) Query: 944 EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 EW +DG + +S + L IK T+ D G Y C N +G +TSA + + Sbjct: 917 EWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLV 974 Score = 37.1 bits (82), Expect = 0.35 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765 ++ EG + C+V P I W +G SR+ + D +L I D Sbjct: 1383 EIDEGSTANLVCKVT-AAKPEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDE 1441 Query: 3766 GEYTCRATNKWGSATTTAKI 3785 G Y TN++G+A++T ++ Sbjct: 1442 GVYKVTLTNEYGTASSTCRV 1461 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/99 (24%), Positives = 43/99 (43%), Gaps = 2/99 (2%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+F+ + E EG + ++ P +EW+K R + SSRI + Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFKSRDNKFT 1625 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868 + + L +D+G Y A NK G + T ++ V + + Sbjct: 1626 MTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664 Score = 37.1 bits (82), Expect = 0.35 Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 3/119 (2%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P+F+ + LV+ + ++ L G P ++EW+ N + + +R + Sbjct: 2157 PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091 + V +DSG Y C+A N G + I K + + +KS+E ++E E Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVE-VKEGE 2272 Score = 37.1 bits (82), Expect = 0.35 Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 2/96 (2%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+FI + V +LV+G + ++ L P ++EW++N + + R + Sbjct: 2157 PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377 + + ++SG Y C A N G S + N+ K Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK 2250 Score = 37.1 bits (82), Expect = 0.35 Identities = 15/50 (30%), Positives = 27/50 (54%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 ++EWYHN + + + SR + + + + +DSG Y C+A+N G Sbjct: 2188 EIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 2237 Score = 37.1 bits (82), Expect = 0.35 Identities = 22/105 (20%), Positives = 49/105 (46%), Gaps = 2/105 (1%) Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047 E+ EG + L+A + +P + WY + + + + +L + + +D+ Sbjct: 3051 ELQEGDTITLDAVVK--GNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDS 3108 Query: 2048 GTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092 G Y C N VG A + +V V+AK + ++L++++ ++ Sbjct: 3109 GVYKCVLKNKVGTATKSFTVDVEAKKSKGIIPEFFRQLRRVEAVQ 3153 Score = 37.1 bits (82), Expect = 0.35 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 1/64 (1%) Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DT 1427 +L L V P+DSGVY C N++G A S + V AKK + + L +++ ++ T Sbjct: 3097 SLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKSKGIIPEFFRQLRRVEAVQGST 3156 Query: 1428 SRYK 1431 +R++ Sbjct: 3157 ARFE 3160 Score = 37.1 bits (82), Expect = 0.35 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 4/110 (3%) Query: 2229 STRIEVEEPKISPPRFVTE-LRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287 S R++V+E ++ PP T+ L G + EG V P+L ++Y +G ++ Sbjct: 3321 SGRLDVKE-RMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDL--QWYKDGVLIRR 3377 Query: 2288 AARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 + ++ SL I VPED G A+N G + + ++ + +K Sbjct: 3378 STHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESK 3427 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702 I T L+ L EG + L V P+L +W+K+GV + + + +L Sbjct: 3335 ISTDVLEGPALLNEGDDLRLVVSVTGNPIPDL--QWYKDGVLIRRSTHISLSSIGSRYSL 3392 Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 +I + +D+G+ C A N G A + ++ IE + Sbjct: 3393 AIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESK 3427 Score = 37.1 bits (82), Expect = 0.35 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 14/94 (14%) Query: 934 EPIGDSTLRVEWLKDG----RPVEASSRITTFFNFGYVA--------LTIKSVTVHDAGH 981 +P+ S R ++G RP E SR F F YV L I T+ D G Sbjct: 5884 DPLASSVSRGRRTRNGNRMARPPETRSRKDLLFRF-YVRKSPERCCHLCISCATIEDEGE 5942 Query: 982 YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPG 1015 YTCRA N G + +A L IV + ++ PG Sbjct: 5943 YTCRASNPAGSCSCTAEL-IVDAPAKVDQAATPG 5975 Score = 36.7 bits (81), Expect = 0.46 Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 6/124 (4%) Query: 2235 EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT 2294 + PK P+ + L G V E + A C + PN E+Y + ++ + R Sbjct: 2 KRPKGDRPQILQPLEGVD-VKEDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSE 58 Query: 2295 FDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTS--AISMTVTAKGSIISESQRPEGLEK 2352 G +L I+ ED GEY N G TS +++ V K S S+ +P E+ Sbjct: 59 VVNGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVPVKPSFTSK-MKPVDAEE 117 Query: 2353 IREL 2356 +E+ Sbjct: 118 GQEV 121 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSLD 2834 F S + + +EG + F+ +V+ S P + W+ + + + R++ +V+L Sbjct: 106 FTSKMKPVDAEEGQEVRFDVHVKGSPKPD--VVWYKGSTMIGTHERFQIVEAAEDHVTLV 163 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864 I+ ED+ Y ATN G T+ LR Sbjct: 164 ISEVKLEDAETYKVVATNDVGKVTSRADLR 193 Score = 36.7 bits (81), Expect = 0.46 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 2/85 (2%) Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970 PE+I G + L V K P I WY NGK+L + + S Sbjct: 201 PEFIDEERGPIDATTGDEVTLTCSVSGKPKPS--ITWYKNGKLLTDSLKLDIRSSGERNW 258 Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEA 2995 + ++ D+ +Y C+A NK G+A Sbjct: 259 VTMLSAKPEDTALYKCEAENKLGKA 283 Score = 36.7 bits (81), Expect = 0.46 Identities = 19/57 (33%), Positives = 27/57 (47%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794 G PK + W +NG + S +L + M PED+ Y C A N+LG+A Sbjct: 227 GKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKA 283 Score = 36.7 bits (81), Expect = 0.46 Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 8/74 (10%) Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG---YVALDIIDLIAE 1512 V EG V + +++ + N V+WFK+G+P+ + R I G +A+ + L E Sbjct: 797 VTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTK-RDIKRRGEEHTLAIHVSSL--E 851 Query: 1513 DSGIYTCRAVNLVG 1526 D+G+Y C A N +G Sbjct: 852 DTGVYKCEASNRLG 865 Score = 36.7 bits (81), Expect = 0.46 Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 2/102 (1%) Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470 S + G+ P+ L + + EG A+ ++T P ++W +G ++ SR + Sbjct: 1364 SAPKTTGEEPIIIRKLQ-AQEIDEGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIK 1421 Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 D L I +D G Y N YG A +T + V Sbjct: 1422 MVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLV 1463 Score = 36.7 bits (81), Expect = 0.46 Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 5/119 (4%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG + C V ++ P I+W + + +R K D SL I +D G+Y Sbjct: 1386 EGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVY 1444 Query: 2847 TCKATNSKGSATTSGSLRC--TGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903 TN G+A+++ + G + I+ Q + + +E E +L+ RP+V Sbjct: 1445 KVTLTNEYGTASSTCRVLVNEVGSRPIF--QQKLKAVSTIEGESTRFEVKLSAMPRPTV 1501 Score = 36.7 bits (81), Expect = 0.46 Identities = 25/97 (25%), Positives = 38/97 (39%), Gaps = 1/97 (1%) Query: 3966 DVDKKQPPRFVTQIQSQTSLVEM-ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTP 4024 +V K+P I S VE+ E + E + G P +EW+ +G + R Sbjct: 2246 NVQPKRPEGTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRRVRS 2305 Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061 + G + + ED G Y C+ N G T A Sbjct: 2306 TLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSA 2342 Score = 36.7 bits (81), Expect = 0.46 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 2/104 (1%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E P F+ P ++EG +A ++ G+ + W KD S ++ Sbjct: 3033 VNERLIPPGFEGPDHGSYELQEGDTITLDAVVK--GNPYPEIRWYKDEFLAMESKKLMLS 3090 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005 +LT+ V D+G Y C N +G AT S + + KK Sbjct: 3091 VRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKK 3134 Score = 36.7 bits (81), Expect = 0.46 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 5/96 (5%) Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA-LDIMSC 1642 L+ VE +G A FE ++ + ++ W + K L R+ + G V L Sbjct: 3146 LRRVEAVQGSTARFECKVSGHPEP--QIAWLKDGKELAI-PRYIKPFYDGEVCKLTFYET 3202 Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE 1678 PED G YTC A N GEA +S ++V SK + E Sbjct: 3203 QPEDEGDYTCVASNEAGEA-SSHASLVLSKPLVMPE 3237 Score = 36.3 bits (80), Expect = 0.61 Identities = 23/96 (23%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 P + P+ + ++ V + E ++A + P+ EW+ + ++ R ++ Sbjct: 4 PKGDRPQILQPLEGVD-VKEDENAILSCTISGTPTPN--AEWYRDSIRVRESRRIKSEVV 60 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 G+ L I E+ GEY+CV N+ G ++KA L Sbjct: 61 NGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPL 96 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 2/98 (2%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 + P F + + EG L +T PT +EW PV R +T ++ Sbjct: 297 DAPSFTIDLTHVRAIEGEESKLVCKVTGKPAPT--IEWLKGELPVTTSLRVRTDFEKNVA 354 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 L I D GTY A N G A + + ++V +S Sbjct: 355 TLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERS 392 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%) Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501 I PRF +S V+EG+ V ++ ++EW K+G+ V + Sbjct: 490 IGPRFEKMKESF-TVVEGESVELVARVTGKPAP--EIEWTKDGKTVRKTNNVDTKERDDQ 546 Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 L I + +DSG+Y C A N GT +++ +L Sbjct: 547 AVLTIEESSRDDSGLYRCTARNKSGTADMTFQL 579 Score = 36.3 bits (80), Expect = 0.61 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTISHVRDEDE 2446 + EG++ R+ G P ++EW ++ K + ++ + TK D V +TI +D Sbjct: 503 VVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAV-LTIEESSRDDS 559 Query: 2447 GVYMCRASNLLG 2458 G+Y C A N G Sbjct: 560 GLYRCTARNKSG 571 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 8/111 (7%) Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEG-----QVEPKNDPDLKIEWYFN 2950 A G+ S D E + E+ + EG ++ EG Q+ K +P+ ++W+ + Sbjct: 766 ASGKATSRADLEVKEREFAPEFEGDE---EGPIVVTEGNEVSIQLRVKANPNADVDWFKD 822 Query: 2951 GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001 G+ + + ++ + TL + D+G+Y C+A N+ G+A S V Sbjct: 823 GRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDV 873 Score = 36.3 bits (80), Expect = 0.61 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 3/109 (2%) Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466 R D V+E + AP F + EG + R+ +PN V+W+ +G+ + Sbjct: 773 RADLEVKEREF-APEFEGDEEGPIVVTEGNEVSIQLRVKA--NPNADVDWFKDGRPIYES 829 Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 ++ L I + ED+G Y C A N G+A + +KVQ K Sbjct: 830 TKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQVK 878 Score = 36.3 bits (80), Expect = 0.61 Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 2/94 (2%) Query: 2497 RSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSR 2556 + P E+PI + L E+ EG A+ +V P +W +GV+++ SR Sbjct: 1362 KQSAPKTTGEEPIIIRKLQA-QEIDEGSTANLVCKVT-AAKPEPSIKWTRDGVKIRENSR 1419 Query: 2557 FRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 + D +L I +D G+Y N G Sbjct: 1420 IKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYG 1453 Score = 36.3 bits (80), Expect = 0.61 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EGD++ V P L EWF ++ L +R + ++ ++ +DSG+Y Sbjct: 1582 EGDDLELTVRVRGKPQPEL--EWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMY 1639 Query: 2847 TCKATNSKGSATTSGSL 2863 C A N GS++ + +L Sbjct: 1640 QCVARNKAGSSSRTFNL 1656 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Query: 3280 EPPKFITQIQDVTKLV-EGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338 +PP F+ T +V EG + A + P+ V W+ +G+ + + T Sbjct: 1860 QPPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPE--VSWYKDGRLVLDSIKQETRKRGD 1917 Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376 L + E++G Y+C A NKLG + N+K S Sbjct: 1918 ESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKVMS 1955 Score = 36.3 bits (80), Expect = 0.61 Identities = 21/83 (25%), Positives = 32/83 (38%) Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 PP F+ + T+ EG P + WY++G+L+ + T Sbjct: 1861 PPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESH 1920 Query: 3889 LDILYVYAEDSGEYICRAVNDFG 3911 L + ED+G Y C A N G Sbjct: 1921 LVVFNAKMEDAGSYKCEANNKLG 1943 Score = 36.3 bits (80), Expect = 0.61 Identities = 17/82 (20%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 I+ KEGD+++ + + P+ ++ W+ + + + + ++ L + + ED Sbjct: 1873 IIVKEGDDLNISATI--AGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMED 1930 Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864 +G Y C+A N G+ T + +++ Sbjct: 1931 AGSYKCEANNKLGTVTKTYNVK 1952 Score = 36.3 bits (80), Expect = 0.61 Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYIS 695 P+ + L+ V + G + F+ R+ G P ++W + + I + GY S Sbjct: 2647 PRILEKLQDVDSSVGERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFS 2704 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 L + ++ +D G Y ++ +G + AVL + Sbjct: 2705 LTIEYIDYEDEGAYKAVVINDSGEVSSTAVLRL 2737 Score = 36.3 bits (80), Expect = 0.61 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 3/123 (2%) Query: 1019 KIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTV 1077 K L ++ + S R E V P F GP G+ ++ EG + +A V+ + + Sbjct: 3015 KCTALNESGKSSTRAELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVK--GNPYPEI 3072 Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137 WY + + ++ +L + V +DSGVY V +N G A S ++ VE Sbjct: 3073 RWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEA 3132 Query: 1138 RSS 1140 + S Sbjct: 3133 KKS 3135 Score = 36.3 bits (80), Expect = 0.61 Identities = 35/126 (27%), Positives = 51/126 (40%), Gaps = 9/126 (7%) Query: 2905 DTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRF 2960 D E K + IIP + V+G E +V P+ +I W +GK L Sbjct: 3129 DVEAKKSKGIIPEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYI 3186 Query: 2961 KLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS---KDNLIERTQHPK 3017 K D L + D G YTC A N+ GEA + +++ + ER ++ K Sbjct: 3187 KPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASLVLSKPLVMPEFKERLKNIK 3246 Query: 3018 GTEGLE 3023 EG E Sbjct: 3247 VVEGDE 3252 Score = 36.3 bits (80), Expect = 0.61 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 4/97 (4%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGFV 1235 P F + L N V EG R++ G+P +VEWF G+ + +RF + + Sbjct: 3236 PEFKERLKNIKVV-EGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 L I D G Y A N G S + V ER Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/104 (25%), Positives = 42/104 (40%), Gaps = 1/104 (0%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E PE T + + ++ G + G+ ++W KDG + S+ I+ Sbjct: 3326 VKERMVPPEISTDVLEGPALLNEG-DDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLS 3384 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005 +L I V D G C A N G A+ S + I +KK Sbjct: 3385 SIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKK 3428 Score = 36.3 bits (80), Expect = 0.61 Identities = 48/246 (19%), Positives = 92/246 (37%), Gaps = 12/246 (4%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFT-PIYDFGYV 4031 P F+ ++Q +VE + ++ V +P +++W+ + + + R + G Sbjct: 3735 PSFLQRMQD-LEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEEDGLC 3791 Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKA--VIKTTGKPGIVYDSQLPKHMKSIEKIRE 4089 + D G Y C +N G + A I+T G V D+ L + + Sbjct: 3792 MLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEAREST 3851 Query: 4090 MEASWQVTPEQVVEESKAR---CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL 4146 +E T ++ E + PP F + V+EG +F RV +V W Sbjct: 3852 IELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVISKAPIKVEWYK 3911 Query: 4147 NGNTIVNG-SRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHD 4204 + I + R+ +D +Y +I + D G + L V+P + Sbjct: 3912 DDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESKAYLNVLPEME 3971 Query: 4205 -DYRGV 4209 ++ G+ Sbjct: 3972 PEFEGI 3977 Score = 36.3 bits (80), Expect = 0.61 Identities = 18/45 (40%), Positives = 25/45 (55%) Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808 D GEYTCRA+N GS + TA++ A + + G+ G KI Sbjct: 5939 DEGEYTCRASNPAGSCSCTAELIVDAPAKVDQAATPGSGVVGGKI 5983 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/96 (23%), Positives = 37/96 (38%), Gaps = 2/96 (2%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G+ P+ + + E+ +A C + + EW+ + + R+K+ G Sbjct: 6 GDRPQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGM 63 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 L I D G Y C N HG AT L V+ Sbjct: 64 ATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99 Score = 35.9 bits (79), Expect = 0.80 Identities = 54/222 (24%), Positives = 90/222 (40%), Gaps = 38/222 (17%) Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499 V +KP F ++ K ++ EGQ V F+ ++ + V W+K + RF+ + Sbjct: 100 VPVKPSFTSKMKPVD-AEEGQEVRFDVHVKGSPKPD--VVWYKGSTMIGTHERFQIVE-- 154 Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559 A D + L+ + + +V T++V ++T R+ +R + + E I E Sbjct: 155 --AAEDHVTLVISEVKLEDAETYKVVATNDVG-KVTSRAD---LRVKERQFAPEFID--E 206 Query: 1560 DRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKP 1619 +R T DEVT C+ S K P T WY N K Sbjct: 207 ERGPIDATTG-DEVTLT---CSVSGK-----------------PKPSIT----WYKNGKL 241 Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 L + ++ + ++S PED+ Y C A N LG+A Sbjct: 242 LTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKA 283 Score = 35.9 bits (79), Expect = 0.80 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 3/101 (2%) Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471 V+ KG+AP+ L +E EGE + + T T P EW +G +++ + Sbjct: 877 VKGPKGEAPIILSKLRPVET-EEGEET--KLKCTFTGKPAPTCEWTRDGIRIRSSRMVQI 933 Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 L I T +D G Y C N+ G T+A + V Sbjct: 934 DTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLV 974 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/102 (25%), Positives = 42/102 (41%), Gaps = 3/102 (2%) Query: 3552 AESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND 3611 A G P FT+ S + + E + + V+W +G P+ R+ + Sbjct: 1957 APEGQAPSFTSEMSQVEVDEGGEV--KLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSS 2014 Query: 3612 -FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 V L I V + D G+Y C N+HG T + ++ V R Sbjct: 2015 RVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQR 2056 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV-A 1369 P F + + N+E G +V E +++ G V + + I G R+ E + + Sbjct: 2060 PIFGQKMKNVEGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFV 2117 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + + PED+G Y C A N GE + L V Sbjct: 2118 LTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHV 2150 Score = 35.9 bits (79), Expect = 0.80 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 7/115 (6%) Query: 1310 APQFSRALHN--IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367 AP+F I EG L+ L+ + +V W+ +GK R + Sbjct: 2449 APEFETGEERGPIVVPEGGETTLKVTLR--ANPKPQVIWYKDGKHTSENIRLDVRSRGNT 2506 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422 L + + EDSG Y C+A N+LG A S +RV K + P+ L+++Q Sbjct: 2507 HYLKITNAKIEDSGSYKCEARNKLGFADKSFTIRVEVPKP---TGEEPTILQRLQ 2558 Score = 35.9 bits (79), Expect = 0.80 Identities = 36/147 (24%), Positives = 58/147 (39%), Gaps = 4/147 (2%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 P P+ + +++ ++ EG S R+ P +EW+ + L R H Sbjct: 2842 PGEAAPEIVQRLK-ACEVPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHT 2898 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK 3396 L+ L + G Y VA N LG ST A L + +E E Sbjct: 2899 GDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVSPPSFRHRLTAVEVD-EG 2957 Query: 3397 LQTLEDSMVRRKDTSVEEEKGKAPVFT 3423 +T D ++++ TSVE K + +FT Sbjct: 2958 DETRFDVRLKKEPTSVEWYKEQQRIFT 2984 Score = 35.9 bits (79), Expect = 0.80 Identities = 20/62 (32%), Positives = 31/62 (50%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 ++WY +G I + I +L I V ED+GV VA N AG A S ++ +E Sbjct: 3366 LQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIE 3425 Query: 1137 TR 1138 ++ Sbjct: 3426 SK 3427 Score = 35.5 bits (78), Expect = 1.1 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 8/135 (5%) Query: 1007 IIAESQHPGGLEKIQYLEDASRYSKRTEEEVKIT------QKPRFLGPLKGTNKIVEGQS 1060 I+ G+ K Q A S+ E +VK + ++P + L+ +I EG + Sbjct: 1331 IVRAKLSDAGVYKCQATNAAGSASRSWEVKVKQSAPKTTGEEPIIIRKLQA-QEIDEGST 1389 Query: 1061 AHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVA 1120 A+ +V +++W +G +I +RI+ D +L I +D GVY V Sbjct: 1390 ANLVCKVTAAKP-EPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVTL 1448 Query: 1121 RNAAGEAQLSASMTV 1135 N G A + + V Sbjct: 1449 TNEYGTASSTCRVLV 1463 Score = 35.5 bits (78), Expect = 1.1 Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 4/120 (3%) Query: 2924 VEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSD--FGFVTLDLVDVYERDS 2981 +EG+ E ++ P +EW+ + + G RF +T + G L + D D+ Sbjct: 1482 IEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDA 1539 Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD 3041 G Y AYN G+ + + + + E +G + +LE ++R QP+ Sbjct: 1540 GTYKVVAYNNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEKTEGDDLELTVRVRGKPQPE 1599 Score = 35.5 bits (78), Expect = 1.1 Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 9/131 (6%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885 V T P+F+ + + +E++EG E V + P+ +EW++ + L R Sbjct: 1564 VLTVPEFMDKAEG-PIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDN 1622 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK------LPDIILQNQVPRGMKR 3939 ++ + + +DSG Y C A N G + +K PDII + + + +K Sbjct: 1623 KFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVIGNAPDII-THLISKEVKE 1681 Query: 3940 SEALTQMEATI 3950 +T +E T+ Sbjct: 1682 GGTVT-LECTV 1691 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 5/91 (5%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS---YVS 2832 F L + EG F+ ++ P ++EW+ + R++ T + S Sbjct: 1765 FKQKLRPLEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITEPYEGDDTYS 1822 Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 L I +T ED+ +Y C A N G T L Sbjct: 1823 LIILNTTMEDAAMYKCVAFNEAGKTTCRADL 1853 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH--DFGY 2166 P F LT++E + EGD F+ R++ +P +++W+ Q+I + + Sbjct: 2943 PSFRHRLTAVE-VDEGDETRFDVRLK--KEP-TSVEWYKEQQRIFTDGHFEVIEGEEECL 2998 Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 +L I T D+G Y C A N+ G++ L V Sbjct: 2999 YSLVISNTKVADAGGYKCTALNESGKSSTRAELLV 3033 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSL 2833 F L + EGD F+ ++ ++PT +EW+ + + + ++ + SL Sbjct: 2945 FRHRLTAVEVDEGDETRFDVRLK--KEPT-SVEWYKEQQRIFTDGHFEVIEGEEECLYSL 3001 Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 I++T D+G Y C A N G ++T L Sbjct: 3002 VISNTKVADAGGYKCTALNESGKSSTRAEL 3031 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 3/86 (3%) Query: 2650 SYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRN 2709 SY+ L EG + L+A V + +P +I W+K+ +L + +L++ + Sbjct: 3049 SYE-LQEGDTITLDAVV--KGNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIP 3105 Query: 2710 DDSGIYTCKATNLLGEAVSTASIKIE 2735 DSG+Y C N +G A + ++ +E Sbjct: 3106 KDSGVYKCVLKNKVGTATKSFTVDVE 3131 Score = 35.5 bits (78), Expect = 1.1 Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 6/114 (5%) Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180 L+EGD + V+ +P+ I W+ + + + +L + + +DSG Sbjct: 3052 LQEGDTITLDAVVK--GNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSG 3109 Query: 2181 TYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA-QGHSTRIE 2233 Y C NK+G A + T+ V ++ + P ++R++EA QG + R E Sbjct: 3110 VYKCVLKNKVGTATKSFTVDVEAKKSKGI---IPEFFRQLRRVEAVQGSTARFE 3160 Score = 35.1 bits (77), Expect = 1.4 Identities = 18/65 (27%), Positives = 32/65 (49%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P + WYK+G+ +T S ++ + + ++ + ED Y A NKLG+A Sbjct: 229 PKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFD 288 Query: 860 IRVAA 864 ++V A Sbjct: 289 VKVKA 293 Score = 35.1 bits (77), Expect = 1.4 Identities = 40/155 (25%), Positives = 62/155 (40%), Gaps = 11/155 (7%) Query: 3502 GEAVTTASMKVQG--KRNI--ILESQLPKGMEGTIDKIAALEGYSGTVDTLTP--EAESG 3555 GE T S++V+ ++N+ ++ G GT +A + SGT ++ E Sbjct: 335 GELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARND--SGTAHSIAELQVQERS 392 Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615 PE + D+ F+ R+ +VEW + G R + V Sbjct: 393 TKPEIEDSLRDVSALPGERVKFKVRI--GGKPKPKVEWRKGKSVIEDGERFTIAEESDEV 450 Query: 3616 I-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 L I + + DAG Y C ATN GEA +L V Sbjct: 451 FSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 2/69 (2%) Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581 EG+ ARV G P+ EW +G ++ + T L I +D+GLY Sbjct: 505 EGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLY 562 Query: 2582 MCKAINRAG 2590 C A N++G Sbjct: 563 RCTARNKSG 571 Score = 35.1 bits (77), Expect = 1.4 Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 12/127 (9%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQ-------APICTTSLKNVEIKEGQR 1594 I S+++++GL + R+K DM ++ Q AP + L+ VE EG Sbjct: 551 IEESSRDDSGLYRCTA---RNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDD 607 Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654 A + T +EW N +K R G V L I + +D G YTC Sbjct: 608 AVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIV 665 Query: 1655 INALGEA 1661 N LG A Sbjct: 666 RNELGSA 672 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 7/93 (7%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501 P V+ + +E EG C + +PV +EW KNG V R + G Sbjct: 591 PEIVSELRPVE-ATEGDDAVLSCTISGKPVPT----IEWLKNGIRVKDSRRTKCDLVDGE 645 Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 V L I A+D G YTC N +G+ E +L Sbjct: 646 VKLTIKTTRADDQGDYTCIVRNELGSAESKTKL 678 Score = 35.1 bits (77), Expect = 1.4 Identities = 53/222 (23%), Positives = 85/222 (38%), Gaps = 45/222 (20%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF---G 3751 P F ++K + EG V D +VE G P I+W+ R + + G Sbjct: 686 PEFRTKLKP-VKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVESGRFKVMEEEEEDG 742 Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811 +L I + D G ATN G AT+ A + ++KE Sbjct: 743 LYSLVISKLQLDDTGTIKVVATNASGKATSRADL---------------------EVKER 781 Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871 E + +E PIV V E V + RV K +P ++W+++G+ Sbjct: 782 EFAPEFEGDEEGPIV--------------VTEGNEVSIQLRV--KANPNADVDWFKDGRP 825 Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYA-EDSGEYICRAVNDFGE 3912 + + R + G ++V + ED+G Y C A N G+ Sbjct: 826 IYESTK-RDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGK 866 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 2/85 (2%) Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493 EG++ R+ P L EW+ ++L SR + +S +DSG Y Sbjct: 1582 EGDDLELTVRVRGKPQPEL--EWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMY 1639 Query: 3494 LCRAYNNYGEAVTTASMKVQGKRNI 3518 C A N G + T ++ VQ K+ I Sbjct: 1640 QCVARNKAGSSSRTFNLDVQKKKVI 1664 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/88 (28%), Positives = 40/88 (45%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P VE+L++ VP+ S+R + L + + DS TY A N+ G A S Sbjct: 2770 GRPLPTVEFLKDEVPVFKSDRTELTSNGNRHTLYLSDLAVRDSATYKAVAKNKAGVARRS 2829 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLE 1825 L V+ K L+ +Q+++ E Sbjct: 2830 VELLVKPKRGLKPGEAAPEIVQRLKACE 2857 Score = 35.1 bits (77), Expect = 1.4 Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 5/101 (4%) Query: 3554 SGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN--D 3611 S +PP F + + + E F+ RL VEW+ + + T + I + Sbjct: 2939 SVSPPSFRHRLTAVEVDEGDETRFDVRL---KKEPTSVEWYKEQQRIFTDGHFEVIEGEE 2995 Query: 3612 FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 L I DAG Y C A N G+++ +L V R Sbjct: 2996 ECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 6/86 (6%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI--EDSSRITKTHDFGY 2433 P F L ++ + EG FD RL +PT VEW++ ++ I + + + + Sbjct: 2943 PSFRHRLTAVE-VDEGDETRFDVRLKK--EPT-SVEWYKEQQRIFTDGHFEVIEGEEECL 2998 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459 S+ IS+ + D G Y C A N G+ Sbjct: 2999 YSLVISNTKVADAGGYKCTALNESGK 3024 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 4/81 (4%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV- 4031 P F ++++ +VE + +F ++ G+P KVEWF GK + RF+ + Sbjct: 3236 PEFKERLKN-IKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292 Query: 4032 AMNFGWVYPEDSGEYLCRATN 4052 + V ED G Y C A+N Sbjct: 3293 TLTISDVAMEDFGTYKCVASN 3313 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 2/84 (2%) Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841 L EG + +T +P ++WYKDG I S+ I+ SL IM + ED G Sbjct: 3346 LNEGDDLRLVVSVT--GNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTG 3403 Query: 842 SYTVRAVNKLGEAISTASIRVAAR 865 A+N G A + ++ + ++ Sbjct: 3404 VIKCVAMNPAGSASKSFTVVIESK 3427 Score = 34.7 bits (76), Expect = 1.9 Identities = 17/55 (30%), Positives = 24/55 (43%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G P+ EWY + + ++ R ++ G TL I A D G Y C N G Sbjct: 34 GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTRAEDQGEYKCVLRNEHG 88 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 2/93 (2%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F+ P + G + L C + G P + W+ NG+ +T + Sbjct: 201 PEFIDEERGPIDATTGDEVTLTCSVS--GKPKPSITWYKNGKLLTDSLKLDIRSSGERNW 258 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269 + ++ A DT Y A N LG A + V+V Sbjct: 259 VTMLSAKPEDTALYKCEAENKLGKASRAFDVKV 291 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 2/74 (2%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576 P E EG A + G P EW NG+ +K R + G V L I + A+ Sbjct: 599 PVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRAD 656 Query: 2577 DAGLYMCKAINRAG 2590 D G Y C N G Sbjct: 657 DQGDYTCIVRNELG 670 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 3270 QQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329 +Q P T + E P I ++Q ++ EG +A+ + V P+ ++W +G K+ Sbjct: 1362 KQSAPKT-TGEEPIIIRKLQ-AQEIDEGSTANLVCK-VTAAKPEPSIKWTRDGVKIRENS 1418 Query: 3330 RYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDST 3368 R + D L I ++ G Y+ TN+ G S+ Sbjct: 1419 RIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASS 1457 Score = 34.7 bits (76), Expect = 1.9 Identities = 19/77 (24%), Positives = 37/77 (48%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 +EWF + L SR+ + + + + D+G+Y C A N+ G ++ + L V+ Sbjct: 1600 LEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQ 1659 Query: 3651 GRQGIILEPQLPSHFKS 3667 ++ I P + +H S Sbjct: 1660 KKKVIGNAPDIITHLIS 1676 Score = 34.7 bits (76), Expect = 1.9 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 5/95 (5%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR--FTSIFR-FGY 693 P+F L+ + +EG + F+ RI+ P ++EW + I S R T + Sbjct: 1763 PEFKQKLRPLEVVEGSEAKFDVRIKSY--PKPEVEWYRGTTKITDSLRHQITEPYEGDDT 1820 Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 SL +L+ ++D+ Y C A + G +A L V Sbjct: 1821 YSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTV 1855 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579 EG A + V G P+ + EW EL+ G R D L I + D+G Sbjct: 3540 EGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSG 3597 Query: 2580 LYMCKAINRAG 2590 Y C A N+AG Sbjct: 3598 KYTCIARNKAG 3608 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 6/84 (7%) Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVSLDITHTYEEDSGI 2845 GD + C+V S P I W+ N K L + +S+ + ++V++ ED+ + Sbjct: 216 GDEVTLTCSV--SGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTM--LSAKPEDTAL 271 Query: 2846 YTCKATNSKGSATTSGSLRCTGDK 2869 Y C+A N G A+ + ++ K Sbjct: 272 YKCEAENKLGKASRAFDVKVKAPK 295 Score = 34.3 bits (75), Expect = 2.5 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 2/71 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG+++ V + P +IEW + K + + L I + +DSG+Y Sbjct: 505 EGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLY 562 Query: 2847 TCKATNSKGSA 2857 C A N G+A Sbjct: 563 RCTARNKSGTA 573 Score = 34.3 bits (75), Expect = 2.5 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF--- 964 +PEF+T +K + EG + ++E G +EW + + S R Sbjct: 685 RPEFRTKLKP-VKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVESGRFKVMEEEEED 741 Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 G +L I + + D G A NA G+AT+ A+L + Sbjct: 742 GLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEV 778 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD---Y 1367 P+F L ++ VEG V L+ +++ G +EW+ I RF+ E + Sbjct: 686 PEFRTKLKPVKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGL 743 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 +L + + +D+G ATN G+A + L V Sbjct: 744 YSLVISKLQLDDTGTIKVVATNASGKATSRADLEV 778 Score = 34.3 bits (75), Expect = 2.5 Identities = 18/75 (24%), Positives = 38/75 (50%), Gaps = 2/75 (2%) Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705 + EG ++ + R++ +P ++W K+G+ I S++ R +L + +++D Sbjct: 795 IVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLED 852 Query: 706 SGEYTCRAVSATGVA 720 +G Y C A + G A Sbjct: 853 TGVYKCEASNRLGKA 867 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 6/91 (6%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSG--TRYKSTHDFSYVS 2832 + +S L + +EG+ +C PT EW + + S + +T D S + Sbjct: 886 IILSKLRPVETEEGEETKLKCTFTGKPAPTC--EWTRDGIRIRSSRMVQIDTTEDSS--T 941 Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 L I T +D G+Y C N G+ +TS + Sbjct: 942 LIIKETTLDDEGLYKCTIKNDLGTVSTSAEV 972 Score = 34.3 bits (75), Expect = 2.5 Identities = 17/55 (30%), Positives = 22/55 (40%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G P+ EWY +G+ R TT D ++ D G Y C A N G Sbjct: 1693 GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLG 1747 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248 V EG ++++ + G P+ V W+ +GR V + +T L + +A D G Sbjct: 1875 VKEGDDLNISATIA--GKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932 Query: 1249 EYTVRAVNHLGSAHTSAIVRVI 1270 Y A N LG+ + V+V+ Sbjct: 1933 SYKCEANNKLGTVTKTYNVKVM 1954 Score = 34.3 bits (75), Expect = 2.5 Identities = 30/128 (23%), Positives = 49/128 (38%), Gaps = 4/128 (3%) Query: 1149 GLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPT 1208 G+Y+ T + + I +P+F Q + N G+++ E ++E G P Sbjct: 2032 GVYKCTIQNQHGSTTTTVQVIVTQRSIRPIFGQKMKNVEG-RIGEDVRFEIQVE--GTPV 2088 Query: 1209 MRVEWFHNGRSVTVGSRFKTYYDF-GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267 V + + G R+ + G L I + D GEY AVN G + + Sbjct: 2089 PAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYL 2148 Query: 1268 RVIERSDI 1275 V E I Sbjct: 2149 HVEEELTI 2156 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 6/94 (6%) Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF- 1499 +I+P F + K++E I G+ V FE ++E V + + + + G R+ + + Sbjct: 2057 SIRPIFGQKMKNVEGRI-GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEEN 2113 Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR 1533 G L I + ED+G Y C AVN G EV+ + Sbjct: 2114 GLFVLTIRNTRPEDAGEYQCIAVN--GAGEVTSK 2145 Score = 34.3 bits (75), Expect = 2.5 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 4/88 (4%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GFI 3753 P F ++K N++ G V F+ +VE G P + + G R + + G Sbjct: 2060 PIFGQKMK-NVEGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSIVEEENGLF 2116 Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATT 3781 L I DAGEY C A N G T+ Sbjct: 2117 VLTIRNTRPEDAGEYQCIAVNGAGEVTS 2144 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 2/71 (2%) Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158 E V E +AR P + L D V GE A F RV+G P P V W I Y Sbjct: 2637 ELTVLEREAR-PRILEKLQD-VDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYI 2694 Query: 4159 LTYDGMYHFDI 4169 + +G +F + Sbjct: 2695 VRDEGRGYFSL 2705 Score = 34.3 bits (75), Expect = 2.5 Identities = 19/69 (27%), Positives = 33/69 (47%) Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397 G+ ++W+ +G I+ + +L ++ V PED+GV C A N G A S Sbjct: 3360 GNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKS 3419 Query: 1398 CALRVIAKK 1406 + + +KK Sbjct: 3420 FTVVIESKK 3428 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Query: 2499 EEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR 2558 E +REF P F GP + EG + RV +P+ +W+ +G + ++ Sbjct: 777 EVKEREFA-PEFEGDEEGPIVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTKRD 833 Query: 2559 TTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 TL I+ D G+Y C+A NR G Sbjct: 834 IKRRGEEHTLAIHVSSLEDTGVYKCEASNRLG 865 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 2/102 (1%) Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763 +EV+T P F M + + + + E + G P+ +EW + + S+R+ Sbjct: 1562 NEVLT-VPEF-MDKAEGPIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKS 1619 Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + + + +DSG Y C A N+ G + + L VQ K Sbjct: 1620 RDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKK 1661 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 2/93 (2%) Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631 +V AP T L + E+KEG E + +EWY + + R T + Sbjct: 1662 KVIGNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFD 1719 Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664 ++ D G Y C A N LG A +S Sbjct: 1720 GSVASVTFTDAQGFDDGEYKCVATNPLGSAQSS 1752 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 4/100 (4%) Query: 768 QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT-SIFNFG 826 Q P F + + E+ EG ++ PT V+W +DG P+ RI+ Sbjct: 1961 QAPSFTSEMSQV-EVDEGGEVKLYFLISGYPKPT--VKWTRDGIPVFEDYRISMDSSRVQ 2017 Query: 827 YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866 V+L I ++ D G Y N+ G +T + V RS Sbjct: 2018 GVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS 2057 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 3/77 (3%) Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIVILDILYCYEENSGEY 3355 G+ FE ++ P V + +++ G RY + G+ +L I E++GEY Sbjct: 2074 GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEY 2131 Query: 3356 ECVATNKLGRDSTKANL 3372 +C+A N G ++K L Sbjct: 2132 QCIAVNGAGEVTSKGYL 2148 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 5/91 (5%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKV-EWYHNNKPLKS-GSRFTETNNFGFV 1635 P L++V+ G+RA F+ R VS + + V +WY ++ + + G G+ Sbjct: 2647 PRILEKLQDVDSSVGERAMFKIR---VSGSPMPVVQWYRRDEEITTKGHYIVRDEGRGYF 2703 Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666 +L I ED G Y IN GE ++ + Sbjct: 2704 SLTIEYIDYEDEGAYKAVVINDSGEVSSTAV 2734 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/91 (27%), Positives = 37/91 (40%), Gaps = 3/91 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P V R K+ E V EG C++ +EW+K+ P+ R H Sbjct: 2847 PEIVQRLKACE-VPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQYF 2903 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 L+ ++ A D G Y A N +G+ S L Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAEL 2934 Score = 33.9 bits (74), Expect = 3.2 Identities = 35/150 (23%), Positives = 56/150 (37%), Gaps = 11/150 (7%) Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578 E+ EG RV G P+ EWY + + LK R H L+ A D Sbjct: 2857 EVPEGSSFKLRCRVT--GTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDE 2914 Query: 2579 GLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGV 2638 G YM A N G II+ ++ P S+ +L +++ E D + Sbjct: 2915 GRYMLVAKNHLG-------SVSTSAELIIEPSVSPPSFRH-RLTAVEVDEGDETRFDVRL 2966 Query: 2639 QQAPIFTTHLKSYDKL-VEGQHVYLEAQVE 2667 ++ P K ++ +G +E + E Sbjct: 2967 KKEPTSVEWYKEQQRIFTDGHFEVIEGEEE 2996 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 2/74 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EGD++ +V + +P ++W+ + + T + S SL I ED+G+ Sbjct: 3348 EGDDLRLVVSV--TGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVI 3405 Query: 2847 TCKATNSKGSATTS 2860 C A N GSA+ S Sbjct: 3406 KCVAMNPAGSASKS 3419 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 2/64 (3%) Query: 2397 DCRLIP--VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454 D RL+ G+P ++W+++ LI S+ I+ + S+ I V ED GV C A Sbjct: 3351 DLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAM 3410 Query: 2455 NLLG 2458 N G Sbjct: 3411 NPAG 3414 Score = 33.9 bits (74), Expect = 3.2 Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 7/133 (5%) Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLK--VTQPDQADNLPALTP-----LRDIVVYEGQPAQF 4740 EDE D + A K++ V++P + + PA P L D V EG+ Sbjct: 4611 EDELDAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSL 4670 Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 ++ + K + W R+ + + +I G+ L I +D + AT A+G Sbjct: 4671 DVKLPQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASG 4730 Query: 4801 QVETSAKLVVKSK 4813 +++V+ + Sbjct: 4731 TTSCDCEVLVEER 4743 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL-TYDGMYHFDIPKTRQYD 4176 + V V+E E A C ++G P P W + + R K +GM I +TR D Sbjct: 16 EGVDVKEDENAILSCTISGTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTRAED 75 Query: 4177 TGKIEVI 4183 G+ + + Sbjct: 76 QGEYKCV 82 Score = 33.5 bits (73), Expect = 4.3 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 4/85 (4%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566 KP L S L G+ ++ R+ G P + EW ++ G RF + V Sbjct: 394 KPEIEDSLRDVSAL-PGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEV 450 Query: 2567 -TLDINSVVANDAGLYMCKAINRAG 2590 +L I + DAG Y C A N AG Sbjct: 451 FSLIIQDLEETDAGRYKCVATNEAG 475 Score = 33.5 bits (73), Expect = 4.3 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 5/91 (5%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK---STHDFSYVS 2832 F + L + EG+ + + VE P IEW+ + R+K + S Sbjct: 688 FRTKLKPVKAVEGEEVQLDVKVEGYPKPD--IEWYRGTTMIVESGRFKVMEEEEEDGLYS 745 Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 L I+ +D+G ATN+ G AT+ L Sbjct: 746 LVISKLQLDDTGTIKVVATNASGKATSRADL 776 Score = 33.5 bits (73), Expect = 4.3 Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 4/133 (3%) Query: 1139 SSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLE 1198 SS++ + +++ R + S+ + Q++ P+ + L P EG+ L+ Sbjct: 848 SSLEDTGVYK-CEASNRLGKASRSFDVKVQVKGPKGEAPIILSKL-RPVETEEGEETKLK 905 Query: 1199 CRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHL 1258 C G P EW +G + + L I T D G Y N L Sbjct: 906 CTFT--GKPAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDL 963 Query: 1259 GSAHTSAIVRVIE 1271 G+ TSA V V E Sbjct: 964 GTVSTSAEVLVNE 976 Score = 33.5 bits (73), Expect = 4.3 Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 5/94 (5%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD--FGY 4030 P F ++++ S +E E+T+FE +L+ + P VEWF + + RFT + G Sbjct: 1470 PIFQQKLKA-VSTIEGESTRFEVKLSAM--PRPTVEWFKSSSQIYDGGRFTITEEENSGV 1526 Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064 + ED+G Y A N G ++A+++ Sbjct: 1527 YVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLR 1560 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 5/80 (6%) Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF---GFVALDIM 1640 L+ +E+ EG A F+ R+ S +VEWY + R T + +L I+ Sbjct: 1769 LRPLEVVEGSEAKFDVRI--KSYPKPEVEWYRGTTKITDSLRHQITEPYEGDDTYSLIIL 1826 Query: 1641 SCLPEDSGTYTCRAINALGE 1660 + ED+ Y C A N G+ Sbjct: 1827 NTTMEDAAMYKCVAFNEAGK 1846 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491 ++EG++ + A T P+ +V WY +G+ + + T L + ED+G Sbjct: 1875 VKEGDDLNISA--TIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932 Query: 3492 EYLCRAYNNYGEAVTTASMKV 3512 Y C A N G T ++KV Sbjct: 1933 SYKCEANNKLGTVTKTYNVKV 1953 Score = 33.5 bits (73), Expect = 4.3 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 3/88 (3%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P V W ++G + S + T L + ED+G+Y C A N+LG + Sbjct: 1889 GKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKT 1948 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLE 1825 + V S A E Q S ++ Q+E Sbjct: 1949 YNVKVMSTAP---EGQAPSFTSEMSQVE 1973 Score = 33.5 bits (73), Expect = 4.3 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 5/94 (5%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYV 1368 P F L +E EG + RL+ + VEW+ + I T F E Sbjct: 2943 PSFRHRLTAVEVDEGDETRFDVRLKK---EPTSVEWYKEQQRIFTDGHFEVIEGEEECLY 2999 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 +L + + D+G Y C A N+ G++ T L V Sbjct: 3000 SLVISNTKVADAGGYKCTALNESGKSSTRAELLV 3033 Score = 33.5 bits (73), Expect = 4.3 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 4/76 (5%) Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNN-KPLPSGTRYKSTHDFSYVSLDITHTYEEDSG 2844 +EGD I + V+ + P +I W+ + + S S D SL + H +DSG Sbjct: 3053 QEGDTITLDAVVKGNPYP--EIRWYKDEFLAMESKKLMLSVRDRKN-SLTLYHVIPKDSG 3109 Query: 2845 IYTCKATNSKGSATTS 2860 +Y C N G+AT S Sbjct: 3110 VYKCVLKNKVGTATKS 3125 Score = 33.5 bits (73), Expect = 4.3 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 2/105 (1%) Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471 V+E + T L L EG++ +T P+L +WY +G ++ + Sbjct: 3326 VKERMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDL--QWYKDGVLIRRSTHISL 3383 Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516 L I PED+G C A N G A + ++ ++ K+ Sbjct: 3384 SSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKK 3428 Score = 33.1 bits (72), Expect = 5.7 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 5/109 (4%) Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLR 2541 E K+ K + + + + P + + P FT LT + EG+ + +V G P+ Sbjct: 275 EAENKLGKASRAFDVKVKAP--KGDAPSFTIDLTHVRAI-EGEESKLVCKVT--GKPAPT 329 Query: 2542 FEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 EW + + R RT + TL I DAG Y A N +G Sbjct: 330 IEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSG 378 Score = 33.1 bits (72), Expect = 5.7 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 13/109 (11%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLV--DVYE 2978 ++VEG + ++ K+ P ++EWY + R ++T + G T L+ + Sbjct: 1773 EVVEGSEAKFDVRI--KSYPKPEVEWYRGTTKITDSLRHQITEPYEGDDTYSLIILNTTM 1830 Query: 2979 RDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK--GTEGLEKI 3025 D+ +Y C A+N+ G+ C + +IE+ Q P G +G + I Sbjct: 1831 EDAAMYKCVAFNEAGK------TTCRADLTVIEKQQPPTFLGDDGTQTI 1873 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/85 (23%), Positives = 40/85 (47%), Gaps = 4/85 (4%) Query: 636 PPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693 PP F+ +++ EG ++ I G P+ ++ W K+G+ + S + + R Sbjct: 1861 PPTFLGDDGTQTIIVKEGDDLNISATI--AGKPSPEVSWYKDGRLVLDSIKQETRKRGDE 1918 Query: 694 ISLDMLSLNIQDSGEYTCRAVSATG 718 L + + ++D+G Y C A + G Sbjct: 1919 SHLVVFNAKMEDAGSYKCEANNKLG 1943 Score = 33.1 bits (72), Expect = 5.7 Identities = 32/127 (25%), Positives = 48/127 (37%), Gaps = 8/127 (6%) Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475 +G+AP FT +S +E + EG ++ P +K W + +R D Sbjct: 1959 EGQAPSFTSEMSQVE-VDEGGEVKLYFLISGYPKPTVK----WTRDGIPVFEDYRISMDS 2013 Query: 3476 GFV---ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTI 3532 V L I D G Y C N +G TT + V + + Q K +EG I Sbjct: 2014 SRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRSIRPIFGQKMKNVEGRI 2073 Query: 3533 DKIAALE 3539 + E Sbjct: 2074 GEDVRFE 2080 Score = 33.1 bits (72), Expect = 5.7 Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 14/112 (12%) Query: 1172 ISKSKPVFVQPLSNPPP---------VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222 +S S + ++P +PP V EG + RL+ +PT VEW+ + + Sbjct: 2928 VSTSAELIIEPSVSPPSFRHRLTAVEVDEGDETRFDVRLKK--EPTS-VEWYKEQQRIFT 2984 Query: 1223 GSRFKTYY--DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 F+ + +L I + AD G Y A+N G + T A + V ER Sbjct: 2985 DGHFEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036 Score = 33.1 bits (72), Expect = 5.7 Identities = 17/64 (26%), Positives = 28/64 (43%) Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 T W+ +++ S RI +L I ++ D G Y +V +N GE +TV Sbjct: 5996 TATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVKNDGGEDSCVVKLTV 6055 Query: 1136 ETRS 1139 + S Sbjct: 6056 DDDS 6059 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 7/116 (6%) Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371 P + W+ NGK L + + +L E++ Y+C A NKLG+ S + Sbjct: 229 PKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFD 288 Query: 3372 LKCTSKE----NLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFT 3423 +K + + + +D R +EG KL + + ++E KG+ PV T Sbjct: 289 VKVKAPKGDAPSFTIDLTHVRAIEGEESKLVC---KVTGKPAPTIEWLKGELPVTT 341 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 4/95 (4%) Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101 KP L+ + + G+ F+ R+ + VEW I R + V Sbjct: 394 KPEIEDSLRDVSAL-PGERVKFKVRIGGKPK--PKVEWRKGKSVIEDGERFTIAEESDEV 450 Query: 1102 -ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 +L I + D+G Y VA N AGEA+ A +TV Sbjct: 451 FSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 2/96 (2%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+F + + EG + R+ +P+ V+WF +G+ + + Sbjct: 785 PEFEGDEEGPIVVTEGNEVSIQLRVKA--NPNADVDWFKDGRPIYESTKRDIKRRGEEHT 842 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377 L I E++G Y+C A+N+LG+ S ++K K Sbjct: 843 LAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQVK 878 Score = 32.7 bits (71), Expect = 7.5 Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 5/114 (4%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P ++ E EG L+ T T PT EW +G ++ + Sbjct: 883 EAPIILSKLRPVETEEGEETKLKCTFTGKPAPTC--EWTRDGIRIRSSRMVQIDTTEDSS 940 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDEQRLKKI 2088 L I +D G Y C N +G T++ V V + + G + + E++LK + Sbjct: 941 TLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNEVEKG--VGPVIEEKLKDV 992 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/92 (21%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 4122 VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTGKI 4180 V+EG C V+G P P + W +G R T+DG + + +D G+ Sbjct: 1679 VKEGGTVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEY 1738 Query: 4181 EVIXXXXXXXXXXXXXLKV-IPRHDDYRGVLK 4211 + + L V +P +++ L+ Sbjct: 1739 KCVATNPLGSAQSSARLTVTVPSKPEFKQKLR 1770 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 4/101 (3%) Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFGF 1634 QAP T+ + VE+ EG + T+K W + P+ R + +++ Sbjct: 1961 QAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVK--WTRDGIPVFEDYRISMDSSRVQG 2018 Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675 V L I + D G Y C N G T+ + ++ +++SI Sbjct: 2019 VTLIIRNVTRYDEGVYKCTIQNQHGSTTTT-VQVIVTQRSI 2058 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 IV EG + + + P ++ W+ + K R + L IT+ ED Sbjct: 2461 IVVPEGGETTLKVTLRANPKP--QVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIED 2518 Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864 SG Y C+A N G A S ++R Sbjct: 2519 SGSYKCEARNKLGFADKSFTIR 2540 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/100 (23%), Positives = 40/100 (40%), Gaps = 3/100 (3%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 R + +P EQ K+ + G A E + G+ + W + + + + M + Sbjct: 4757 RLSQVAPEFMEQC-KSTTVQENGTAIMEVRATGSQPLSIRWFKNQQTIKYGGRIKMSSDG 4815 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164 + +L I + DEG Y C N+ G A C + E Sbjct: 4816 E--HCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTVE 4853 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248 V EG+++ L R+ G P +EW +G++V + T L I ++ D+G Sbjct: 503 VVEGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSG 560 Query: 1249 EYTVRAVNHLGSA 1261 Y A N G+A Sbjct: 561 LYRCTARNKSGTA 573 Score = 32.3 bits (70), Expect = 9.9 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 6/95 (6%) Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH--KN 4020 DL +++ P F + + +V E + QL +PN V+WF +G+P+ K Sbjct: 775 DLEVKEREFAPEF--EGDEEGPIVVTEGNEVSIQLRVKANPNADVDWFKDGRPIYESTKR 832 Query: 4021 RFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055 + +A++ + ED+G Y C A+N G Sbjct: 833 DIKRRGEEHTLAIHVSSL--EDTGVYKCEASNRLG 865 Score = 32.3 bits (70), Expect = 9.9 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 5/87 (5%) Query: 1041 QKPRFLGPLKGTNKIV--EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098 Q P FLG GT I+ EG + A + + + V WY +G+ + + + +T Sbjct: 1860 QPPTFLGD-DGTQTIIVKEGDDLNISATIAGKP--SPEVSWYKDGRLVLDSIKQETRKRG 1916 Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAG 1125 L + + + ED+G Y A N G Sbjct: 1917 DESHLVVFNAKMEDAGSYKCEANNKLG 1943 Score = 32.3 bits (70), Expect = 9.9 Identities = 14/37 (37%), Positives = 19/37 (51%) Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 G LTI++ DAG Y C A N G+ T+ L + Sbjct: 2114 GLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHV 2150 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 2/72 (2%) Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578 E +G A +E +V G P + W +G EL + + +D L D Sbjct: 3150 EAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDE 3207 Query: 2579 GLYMCKAINRAG 2590 G Y C A N AG Sbjct: 3208 GDYTCVASNEAG 3219 Score = 32.3 bits (70), Expect = 9.9 Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 3/100 (3%) Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 PP+ T + +EG V +P ++WY++G L+ S Sbjct: 3332 PPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYS 3391 Query: 3889 LDILYVYAEDSGEYICRAVNDFG---EDFTKATISCKKLP 3925 L I+ V ED+G C A+N G + FT S K P Sbjct: 3392 LAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKKPAP 3431 >SB_8818| Best HMM Match : I-set (HMM E-Value=0) Length = 2787 Score = 199 bits (486), Expect = 4e-50 Identities = 166/603 (27%), Positives = 266/603 (44%), Gaps = 33/603 (5%) Query: 4219 DETTQYQRTET-ELEKTFEERQVLQRQGVIDH--RPELKPKVIKEPETEWQQSVKRKKNE 4275 D+ Y+ T EL T ++L + ++ +PE KPKV K PE E + V++ + E Sbjct: 988 DDEGDYKCVATNELGSTSATTELLVNEKPVEEEKQPE-KPKVEK-PEVE-EPEVEKPEVE 1044 Query: 4276 EYYNKLQELENEQ-VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTE--EV 4332 E + E+E + + L T + + A + D L E E Sbjct: 1045 EPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKPTGEAPKVVDALQPLEALEG 1104 Query: 4333 TEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEI-TRKITSTETTEIE 4391 E ++ K+T P P K V V + K + V I T + + Sbjct: 1105 DEAKLVCKITGSPT-PTVEWFKEKAKVVDVRRTKMEYTDDVATLTIPTTRPEDKGMYKCV 1163 Query: 4392 HKAQTQERVVEGP--VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449 K E + P P F K++P V E A+FEV G P P ++W+ + Sbjct: 1164 AKNDFGEASTSATLHINPVVKPDFKTKLKPMEVTEESVAKFEVRSTGFPQPEVEWFLGST 1223 Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509 I++S F++ + + LII V V+D+ + N+ GTA A+L V+EK Sbjct: 1224 KIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK------ 1277 Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569 P A + V G+ + + ++T +V W K+GK ++ R I D Y Sbjct: 1278 DCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVKWYKDGKPLRDGPRTTIRARDDLY 1337 Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629 +L A P+D+G Y+C A N+ G+A + V +P KP+ + P + L Sbjct: 1338 NCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVEVP----KPR------GSKPSLEAEL 1387 Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689 K V G+ + CKI GKP P + W K DK +KP K + + L +A ED Sbjct: 1388 KPVTVTAGEDTKLVCKISGKPQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLED 1447 Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749 E +YK VA N G V+ +A+L V + A + PL+D+ V G+ A F TQ++ Sbjct: 1448 EAEYKVVAKNELGSVSTSAELLVNEKGAAPKIE--KPLQDVKVDAGKKATFNTQVSGTPT 1505 Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807 P ++W + +++ + F +I + V L+I + ED+G + C G+ +T AK Sbjct: 1506 PEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAK 1565 Query: 4808 LVV 4810 L V Sbjct: 1566 LQV 1568 Score = 193 bits (471), Expect = 3e-48 Identities = 122/449 (27%), Positives = 213/449 (47%), Gaps = 24/449 (5%) Query: 4365 QKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFE 4424 ++ T K + +++ + T E+ T E +V+ ++ P F +KMQP +V E Sbjct: 80 ERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVKETLRK---PEFKQKMQPLQVLE 136 Query: 4425 HEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484 ++ RF+V DG+P P ++W++ I N F+I LII + D+ + + Sbjct: 137 GDEVRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADTYKCI 196 Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544 A + G + C L V+EK P F TA +N+T G + L +V G + Sbjct: 197 ATSEAGKSTCIVELSVKEKTS------APEVFGDTAP-INITEGDELDLSVRVRGKPKPE 249 Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604 + W K+ K ++ R +D L++ +A P+DSG+Y+C A + G A + + V Sbjct: 250 IKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVE 309 Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664 K KPK P+ +PL+ + E + C + G+P PT +W KGD+ +K Sbjct: 310 ----KAKPK------GVAPKFTKPLETLEIMEKETARLECTVTGEPAPTTEWLKGDQPLK 359 Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724 ++ ++ R D L + +DE YK VA N +G T A+L V + + Sbjct: 360 ETQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKK- 418 Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMI--HEGNNAVLLIGN 4782 TP +++ V EG + ++ K +PT+ W + + E F ++ EG+ L+IGN Sbjct: 419 TP-QNVTVLEGDEIRLDARVGGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGN 477 Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 D+G + C+AT G+ A++ ++ Sbjct: 478 AKPLDSGVYICQATNDTGKATAEAEIQIE 506 Score = 174 bits (423), Expect = 2e-42 Identities = 109/412 (26%), Positives = 187/412 (45%), Gaps = 25/412 (6%) Query: 4406 KPS-KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464 KP+ + P T+ +Q E +F G P P+ +W++ + P+++ ++I T Sbjct: 625 KPAGEAPEITESLQEMEELEGNPVTLTCKFTGTPAPVAEWFKASTPVRDGRRYKITTTDN 684 Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524 + L I++ ++D+ + V N G+ K + + +V P FT + V Sbjct: 685 TTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRIT--------ALVRPDFTKKLKPVE 736 Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584 V GQ RLD +V GT +V W K+ R + +EE +YTL+I D Y Sbjct: 737 VEEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTY 796 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIV-AEGQAIEF 4642 +CVA N G+ C + V+ PPEI P + +KIV E + + Sbjct: 797 KCVASNQVGKVTCRGDLKVT-------------EKMFPPEITRPERTEKIVLLEKEELVI 843 Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 + I+G P P V+W+K K I+ S + D YTL I PED G Y C A N G Sbjct: 844 NVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG 903 Query: 4703 RVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761 + +++ P+L + L+ + EG+ A+ + +++ + +PTI+W ++ + Sbjct: 904 TSSTTIDVQIEASKPKGEAPSLVSELQPQEISEGEDAKLECKVSGEPQPTIEWFKDDEPV 963 Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + ++G + L I + +D G + C AT G + +L+V K Sbjct: 964 TTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK 1015 Score = 168 bits (409), Expect = 8e-41 Identities = 109/405 (26%), Positives = 186/405 (45%), Gaps = 21/405 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P FTKK+QP V E E+ + G+P P ++W + +++ + + L I Sbjct: 27 PEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTLKI 86 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 +D + VA N G A + ++V+E R+ P F Q + V G Sbjct: 87 MPSERDDEGEYKCVATNEVGQATITTEVLVKETLRK-------PEFKQKMQPLQVLEGDE 139 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 VR D ++ G V W KN K+ + R +I++E+ Y+L+I + D+ Y+C+A + Sbjct: 140 VRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADTYKCIATS 199 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650 AG++ C E V K +T A PE+ + EG ++ S ++ GKP Sbjct: 200 EAGKSTCIVELSV---------KEKTSA----PEVFGDTAPINITEGDELDLSVRVRGKP 246 Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710 P ++W K DK IK + + DE L +S+A PED G YKC A + G + + Sbjct: 247 KPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDV 306 Query: 4711 KVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769 V + P T PL + + E + A+ + +T + PT +WL+ + ET ++ Sbjct: 307 NVEKAKPKGVAPKFTKPLETLEIMEKETARLECTVTGEPAPTTEWLKGDQPLKETQRIKI 366 Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 + ++ VL + + +D + A +G + A+L+V T Sbjct: 367 ERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEAT 411 Score = 168 bits (408), Expect = 1e-40 Identities = 175/743 (23%), Positives = 300/743 (40%), Gaps = 59/743 (7%) Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155 +T E +V+E+ + P F + V EG+ RF R+ G P P+V W N I N Sbjct: 110 ITTEVLVKETLRK--PEFKQKMQPLQVLEGDEVRFDVRIDGKPTPKVEWFKNRTKIDNEG 167 Query: 4156 RYK-LTYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAP 4214 R++ + + +Y I TR D + I L V + +AP Sbjct: 168 RFEIIDEEDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEK--------TSAP 219 Query: 4215 RPWYDETTQYQRTE-TELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKK 4273 + +T TE EL+ + R +PE+K +P + + K Sbjct: 220 EV-FGDTAPINITEGDELDLSVRVRG--------KPKPEIKWTKDDKPIKKTDRLTTTTK 270 Query: 4274 NEEYYNKLQELENEQVIKESRLRESTHQYAIPG-DKVTSNTVAKSMAQRYEDNLDQTEEV 4332 ++E L + + E + +S H A D K +A ++ L +T E+ Sbjct: 271 DDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPL-ETLEI 329 Query: 4333 TEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQK-EVVGDKE-ITRKITSTE-TTE 4389 E+ + P P+ + G + K+TQ+ ++ DK+ + ++ E E Sbjct: 330 MEKETARLECTVTGEPAPTTEWLKGDQ----PLKETQRIKIERDKDSVVLEVRHVELDDE 385 Query: 4390 IEHK--AQTQERVVEGPV-----KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442 +K A+ + V + ++ P F K Q V E ++ R + G+P P + Sbjct: 386 ALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLEGDEIRLDARVGGKPEPTV 445 Query: 4443 KWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500 W++ + + F I + LII DS V+ A N G A A + + Sbjct: 446 DWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 505 Query: 4501 EEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIR 4559 EE +V P F A + + + L+ VTG +V+W K+ K + D R Sbjct: 506 EEL-------LVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDR 558 Query: 4560 NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE------ARCDAECVVSLPATKDKPK 4613 I + + + I+ P DSG Y+C A N AG + V + + Sbjct: 559 IIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEVLFVAGISQVIGSIR 618 Query: 4614 ---PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670 K A PEI E L++ EG + +CK G P P +W+K ++ + ++ Sbjct: 619 FIVLAKKPAGEAPEITESLQEMEELEGNPVTLTCKFTGTPAPVAEWFKASTPVRDGRRYK 678 Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730 ++ T + TL I E +D +Y+ V N G V ++++T + D L P + Sbjct: 679 ITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKP---V 735 Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790 V EGQ A+ ++ P ++W + +T ++ I EG++ L+I T +D T Sbjct: 736 EVEEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDT 795 Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813 + C A+ G+V L V K Sbjct: 796 YKCVASNQVGKVTCRGDLKVTEK 818 Score = 168 bits (408), Expect = 1e-40 Identities = 195/804 (24%), Positives = 331/804 (41%), Gaps = 89/804 (11%) Query: 3947 EATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMK 4006 EA K TS + K + P V+++Q Q + E E K EC+++ G+P Sbjct: 897 EAQNKMGTSSTTIDVQIEASKPKGEAPSLVSELQPQ-EISEGEDAKLECKVS--GEPQPT 953 Query: 4007 VEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066 +EWF + +P+ NR YD + +D G+Y C ATN G + Sbjct: 954 IEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVN 1013 Query: 4067 GKPGIVYDSQLPKHMK----SIEK--IREMEASWQVTPEQVVEESKARCP-----PVFVS 4115 KP V + + P+ K +E+ + + E V+ + VE P PV V Sbjct: 1014 EKP--VEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVE 1071 Query: 4116 LPDA--VTVE---------------------EGEWARFCCRVTGHPKPRVMWLLNGNTIV 4152 + + +T+E EG+ A+ C++TG P P V W +V Sbjct: 1072 VVETAPITLEDMKPTGEAPKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVV 1131 Query: 4153 NGSRYKLTY-DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIP-RHDDYRGVL 4210 + R K+ Y D + IP TR D G + + L + P D++ L Sbjct: 1132 DVRRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHINPVVKPDFKTKL 1191 Query: 4211 KNAPRPWYDETTQYQRTETELEKT-FEERQVLQRQGVIDHRPELKPKVIKEPETEWQ--Q 4267 K E T+ + E+ T F + +V G + +V+ E + Sbjct: 1192 KPM------EVTEESVAKFEVRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIIS 1245 Query: 4268 SVKRKKNEEYYNKLQELENEQVIK-ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNL 4326 VK K Y L + + +++E GD+ A + R +++ Sbjct: 1246 DVKVKDAGTYKCTLANQAGTAYSRADLKVKEKDCAPEFVGDQ------AAPIVVRQGEDI 1299 Query: 4327 DQTEEVT---EQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKIT 4383 D ++T + V+ KP + D +T+ ++ K + E T Sbjct: 1300 DIGAQITAKPKPNVKWYKDGKP-LRDGPRTTIRARD-----DLYNCKVLSAKPEDTGMYK 1353 Query: 4384 STETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIK 4443 T + +T + VE P P +++P V E + + G+P P I Sbjct: 1354 CEATNAVGKATRTFDVQVEVPKPRGSKPSLEAELKPVTVTAGEDTKLVCKISGKPQPKID 1413 Query: 4444 WYRENFPIKNSPDFQI-HTFSTKS-ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501 W +++ P+K PD ++ T+ ++ +L + +ED A + VA+N G+ SA L+V Sbjct: 1414 WMKDDKPLK--PDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVN 1471 Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561 EK P Q+V V +G+ +T+V+GT +V W K V+ R Sbjct: 1472 EKG-------AAPKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFM 1524 Query: 4562 ILEE--DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619 I+++ +G + L+I +A P+DSG Y+CV N GE + A+ + + A + PK K Sbjct: 1525 IIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAK--LQVDAVEVAPKTDKKL- 1581 Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEY 4678 E EP+ V E Q ++ S K+ GK +P V W+K D +K + ++ Y Sbjct: 1582 ---DEKEEPI---TVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMY 1635 Query: 4679 TLRISEAFPEDEGDYKCVAYNSAG 4702 L +++A +D G Y+C + G Sbjct: 1636 YLTLTDASLDDAGHYRCESTTKLG 1659 Score = 168 bits (408), Expect = 1e-40 Identities = 124/489 (25%), Positives = 218/489 (44%), Gaps = 34/489 (6%) Query: 4332 VTEQRVQK-KVTQKPRI--PDPSESTVHGKEVHVAKQKQTQKEV-VGDKEITRKITSTET 4387 V E+ V++ K +KP++ P+ E V EV + + E VG E+ +++ + T Sbjct: 1012 VNEKPVEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVG--EVPQEVLAPVT 1069 Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447 E+ +T +E + P +QP E ++A+ + G P P ++W++E Sbjct: 1070 VEV---VETAPITLEDMKPTGEAPKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKE 1126 Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507 + + ++ + L I ED ++ VA+N G A SA L + Sbjct: 1127 KAKVVDVRRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHINP----- 1181 Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567 +V P F + + VT + + + + TG +V W K++ R +++ E Sbjct: 1182 ---VVKPDFKTKLKPMEVTEESVAKFEVRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQD 1238 Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627 + L+I + +D+G Y+C N AG A A+ V K+K AP + + Sbjct: 1239 RHELIISDVKVKDAGTYKCTLANQAGTAYSRADLKV-----KEKD-------CAPEFVGD 1286 Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687 +V +G+ I+ +I KP P V+WYK K ++ + D Y ++ A P Sbjct: 1287 QAAPIVVRQGEDIDIGAQITAKPKPNVKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKP 1346 Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITS 4746 ED G YKC A N+ G+ T ++V P + P+L L+ + V G+ + +I+ Sbjct: 1347 EDTGMYKCEATNAVGKATRTFDVQVEVPKPRGSKPSLEAELKPVTVTAGEDTKLVCKISG 1406 Query: 4747 KIKPTIQWLREGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804 K +P I W+++ P PD +++ ++G VL ED + A G V T Sbjct: 1407 KPQPKIDWMKDDK--PLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVST 1464 Query: 4805 SAKLVVKSK 4813 SA+L+V K Sbjct: 1465 SAELLVNEK 1473 Score = 165 bits (400), Expect = 1e-39 Identities = 110/375 (29%), Positives = 175/375 (46%), Gaps = 24/375 (6%) Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501 ++W +++ PI + + LI++ V +D V+ N+ G+A C ANL+V Sbjct: 1671 VEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLIVN 1730 Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561 EK V P N+ V L R + ++ G V W K+ K Sbjct: 1731 EKA-------VKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYK 1783 Query: 4562 ILEEDG--TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619 +LE+ G T+TL++ ++ DSG Y+CVA+N AG+A A V T Sbjct: 1784 MLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEV------------TGRP 1831 Query: 4620 NAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678 AP + + +KD + V GQ + I G P P V WYK DK ++ S+ ++ + Y Sbjct: 1832 CAPTFVEDEVKDAVYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMY 1891 Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738 L I +A D G Y+CVA N+ G V+ ++V +A ++ LR + V+EG Sbjct: 1892 YLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGKAPRF--VSELRPVEVFEGNEV 1949 Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798 +++++ KPT +W R G+ + Q +G + L N ED GT++C A Sbjct: 1950 SLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNV 2009 Query: 4799 AGQVETSAKLVVKSK 4813 G + AKL+VK K Sbjct: 2010 FGSASSQAKLLVKKK 2024 Score = 150 bits (364), Expect = 2e-35 Identities = 120/495 (24%), Positives = 208/495 (42%), Gaps = 33/495 (6%) Query: 4331 EVTEQRVQKKVTQKPRIPDPSESTVHGK-------EVHVAKQKQTQKEVVGDKEITRKIT 4383 EVTE+ V K + P P G V ++ + ++ D ++ K Sbjct: 1195 EVTEESVAKFEVRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKV--KDA 1252 Query: 4384 STETTEIEHKAQTQERVVEGPVKPSK--PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441 T + ++A T + VK P + P V + E + +P P Sbjct: 1253 GTYKCTLANQAGTAYSRADLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPN 1312 Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501 +KWY++ P+++ P I + ED+ ++ A N G A + ++ VE Sbjct: 1313 VKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372 Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561 + +G PS + V VT+G+ +L K++G + W+K+ K ++PD R Sbjct: 1373 VPKPRGS----KPSLEAELKPVTVTAGEDTKLVCKISGKPQPKIDWMKDDKPLKPDKRVL 1428 Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621 + T L +A +D +Y+ VA N G AE +V+ A Sbjct: 1429 PTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVN-------------EKGA 1475 Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE--YT 4679 P+I +PL+D V G+ F+ ++ G P P V+W+KG+ +++ F + A E + Sbjct: 1476 APKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQ 1535 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD--IVVYEGQP 4737 L I +A PED G YKCV +N G AKL+V + A ++ I V E Q Sbjct: 1536 LVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQE 1595 Query: 4738 AQFKTQITSKIKPT-IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796 ++ K P + W ++ + ++ EG L + + +D G + C +T Sbjct: 1596 VDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCEST 1655 Query: 4797 TAAGQVETSAKLVVK 4811 T G ++ ++VK Sbjct: 1656 TKLGTTISTFLIIVK 1670 Score = 149 bits (360), Expect = 7e-35 Identities = 94/316 (29%), Positives = 152/316 (48%), Gaps = 22/316 (6%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P FTKK++P V E ++AR +V G P P ++W+ + ++ ++ LII Sbjct: 726 PDFTKKLKPVEVEEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLII 785 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL---TAQNVNVTS 4527 + +D + VA N+ G C +L V EK + PP T T + V + Sbjct: 786 KTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK-------MFPPEITRPERTEKIVLLEK 838 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 +LV ++ + G DV W K+GK ++ R I TYTL I P+D+G Y C Sbjct: 839 EELV-INVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCE 897 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647 A N G + + V + A+K PK + P ++ L+ + ++EG+ + CK+ Sbjct: 898 AQNKMGTSSTTID--VQIEASK--PKGEA------PSLVSELQPQEISEGEDAKLECKVS 947 Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707 G+P PT++W+K D+ + + TL I +A +DEGDYKCVA N G + Sbjct: 948 GEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSAT 1007 Query: 4708 AKLKVTQ-PDQADNLP 4722 +L V + P + + P Sbjct: 1008 TELLVNEKPVEEEKQP 1023 Score = 145 bits (351), Expect = 9e-34 Identities = 107/408 (26%), Positives = 173/408 (42%), Gaps = 24/408 (5%) Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 K P F +++P VFE + + E P +W R P++ Q S L Sbjct: 1930 KAPRFVSELRPVEVFEGNEVSLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTL 1989 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528 +ED ++ +A+N G+A A L+V++K G P + G Sbjct: 1990 KFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK------GNRPQPIGMIRDIEGYEGG 2043 Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG--TYTLLILEAYPQDSGKYEC 4586 Q R D TG ++ WL +++ + KI E G Y+L++ + +D G+Y C Sbjct: 2044 Q-ARFDVHFTGNPKVE--WLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTC 2100 Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFSCK 4645 VA N +G+A A V KDK AP + + + I E G+ + Sbjct: 2101 VASNESGDATLHANLNV-----KDK-------HIAPMFVEDDTGEPITVEAGKELNVIMN 2148 Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705 I G P P V WYK ++ + +S D Y L + +A P+D G Y+C A N G + Sbjct: 2149 IRGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTAS 2208 Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765 +KV + +T L + + EG +++ K KPTI W R+ + Sbjct: 2209 RTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHTDN 2268 Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 +EG+ + L + D G + C AT + G +SA++ +K K Sbjct: 2269 RVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRK 2316 Score = 142 bits (343), Expect = 8e-33 Identities = 103/395 (26%), Positives = 171/395 (43%), Gaps = 18/395 (4%) Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477 +P V ++ + G P P + WY++ ++ + I + L + + +D Sbjct: 2133 EPITVEAGKELNVIMNIRGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDD 2192 Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537 + ++ A+N+ GTA + + VEE + GRG PSF V + G L +V Sbjct: 2193 AGIYRCEAKNKLGTASRTVMVKVEELK--GRG---VPSFITGLFPVQIKEGDKYTLVCRV 2247 Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 +G + W ++ V D R E L + E D+G Y+C A NS G Sbjct: 2248 SGKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSS 2307 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 AE + K +A P + LK+ E + KI G P PTV++Y Sbjct: 2308 SAEVTI-------------KRKDAIPTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFY 2354 Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717 K LI S+ ++ D +L I+ PED G YKCV N G T A ++V + + Sbjct: 2355 KDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREH 2414 Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777 A + + EG I K +PT+ W+++G +I + + G + Sbjct: 2415 APRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYS 2474 Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812 L+I +ED+G +TC+A ++ G+ S L V++ Sbjct: 2475 LVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEA 2509 Score = 140 bits (340), Expect = 2e-32 Identities = 120/413 (29%), Positives = 172/413 (41%), Gaps = 38/413 (9%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR------ENFPIKNSPDFQIHTFST 4464 P+ K + +V E RFEV+ G P P + WY E K D HTF+ Sbjct: 1736 PVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFT- 1794 Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQN 4522 LI+ DS V+ VA N G A A L V G P+F Sbjct: 1795 ---LIVNDSQRHDSGVYKCVAVNEAGKAISQATLEV-------TGRPCAPTFVEDEVKDA 1844 Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 V V GQ V L + G DV W K+ K++Q KI+ + Y L+I +A DSG Sbjct: 1845 VYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSG 1904 Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642 Y CVA N+ G S+ T D + + P + L+ V EG + Sbjct: 1905 IYRCVAKNTHG----------SVSRTFD---VRVEVDGKAPRFVSELRPVEVFEGNEVSL 1951 Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 CK+ + PT +W + ++ Q S TL+ A ED+G Y C+A N G Sbjct: 1952 VCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFG 2011 Query: 4703 RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 + AKL V + + + + +RDI YEG A+F T P ++WL I Sbjct: 2012 SASSQAKLLVKK--KGNRPQPIGMIRDIEGYEGGQARFDVHFTG--NPKVEWLHGEEQII 2067 Query: 4763 ETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 +++ + L++G+ ED G +TC A+ +G A L VK K Sbjct: 2068 HGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120 Score = 140 bits (340), Expect = 2e-32 Identities = 107/431 (24%), Positives = 186/431 (43%), Gaps = 24/431 (5%) Query: 4389 EIEHKAQTQERVVEGPVKPSKP---PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445 E ++K T R V V+ K P F + P ++ E ++ G+P P I W+ Sbjct: 2199 EAKNKLGTASRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVSGKPKPTITWF 2258 Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRR 4505 R+N P+ + S L ++++ + D+ ++ A N G+ SA + ++ K Sbjct: 2259 RDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKD- 2317 Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565 P+F + + +RLD K+ G V + K+ + R+KILE+ Sbjct: 2318 ------AIPTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILED 2371 Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625 +L+I P+D+G Y+CV N G +E V+ + + P+ Sbjct: 2372 GDRCSLIITNLRPEDAGTYKCVITNLLGVET--SEAVIRVQEREHAPRFDGT-------- 2421 Query: 4626 IEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684 L + A EG + + I GKP PTV W K +I S + + + Y+L I + Sbjct: 2422 --DLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIK 2479 Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQ 4743 ED G+Y C A +S G+ + + LKV P + P+ L+ L + V EG + + Sbjct: 2480 VTKEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGFEFKLIFK 2539 Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803 + + I+W ++G + + +G N L N +D G + C T G+ Sbjct: 2540 VVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESS 2599 Query: 4804 TSAKLVVKSKT 4814 +SA + + KT Sbjct: 2600 SSADISITQKT 2610 Score = 134 bits (323), Expect = 2e-30 Identities = 97/356 (27%), Positives = 151/356 (42%), Gaps = 21/356 (5%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G+P P + W ++ I +S + L+I +V EDS + A + G A S Sbjct: 2443 GKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQS 2502 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555 +L VE + + PPSF + V G +L KV TK + W K+G+ Sbjct: 2503 FDLKVEAPKVKEE----PPSFLSELPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFT 2558 Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615 P ++ + TL A +D+G+Y+C+ N GE+ A+ ++ K Sbjct: 2559 PGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQKTRK------ 2612 Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675 PE I PLK EG F ++ PLP V WY G I +++ ++ Sbjct: 2613 -------PEAIAPLKSIESVEGGQARFDVEMSAFPLPKVDWYHGGTKITHGGRYKIIQST 2665 Query: 4676 DE----YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731 D YTL I D G YKC+A N G T+ + LKV +P A +V Sbjct: 2666 DGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVKEPFIAPEFEGKDITAPMV 2725 Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787 +GQ + +I S+ KP I W ++G + + + G+ L+I +ED Sbjct: 2726 YKDGQDIKVSFKIKSRPKPIIAWYKDGKALTSSKRVTLTSRGDTYELIIKKATKED 2781 Score = 128 bits (309), Expect = 1e-28 Identities = 120/520 (23%), Positives = 212/520 (40%), Gaps = 52/520 (10%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G AK K+ G+PTP V W ++KA +V+ + M Y + +L I P D+G Y Sbjct: 1103 EGDEAKLVCKITGSPTPTVEWFKEKAKVVDVRRTKMEYTDDVA--TLTIPTTRPEDKGMY 1160 Query: 145 TCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR 202 C A+N +GEA S ++I P E+V + G+ Sbjct: 1161 KCVAKNDFGEASTSATLHINP---VVKPDFKTKLKPMEVTEESVAKFEVRSTGFP----- 1212 Query: 203 QTQKVAYTNGTDHSSTDDFKVDTFEYR---LLREVSFRESITKR--YVGESDVQIS-TEI 256 Q + + T + F+V + + R ++ +V +++ T + ++ S ++ Sbjct: 1213 QPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQAGTAYSRADL 1272 Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316 +P + + +++G D Q++ P+P V W+K+G+ L + + I Sbjct: 1273 KVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVKWYKDGKPLRDGPRTTIRA 1332 Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376 + +V + + D+G Y A N G + + VE P + Sbjct: 1333 RDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVEVP----------------KP 1376 Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436 R ++ +E K + VT G+ T+ C+++G+P P++ W +D+ ++ D Sbjct: 1377 RGSKPSLEAELKPVT-----------VTAGEDTKLVCKISGKPQPKIDWMKDDKPLKPD- 1424 Query: 437 NHKILVNESGNHALMITN-VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495 ++L G ++ + L D VA+N+ G + L V EK APK + Sbjct: 1425 -KRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEKG--AAPKIEK 1481 Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG--GASTLDIPRA 553 + V G+ N + GTPTP + W K + I D G L I A Sbjct: 1482 PLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDA 1541 Query: 554 KASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRL 593 K D+ Y+C N G T T+A+L K+L Sbjct: 1542 KPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKL 1581 Score = 128 bits (308), Expect = 1e-28 Identities = 99/405 (24%), Positives = 170/405 (41%), Gaps = 21/405 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F ++ E R +V+ G P P +++Y++ I +S +I + LII Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLII 2379 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 + ED+ + V N G A + V+E+ R T Q+V G Sbjct: 2380 TNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREHAPRF-----DGTDLGQSVTAQEGFE 2434 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 + + G V W+K+G + + + +Y+L+I++ +DSG Y C A++ Sbjct: 2435 LNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVS 2494 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650 S G+A + V P K++P P + L V EG + K+V Sbjct: 2495 SLGKASQSFDLKVEAPKVKEEP----------PSFLSELPPLQVREGFEFKLIFKVVTTK 2544 Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710 ++W K + P + S TL A +D G Y+C+ N G + +A + Sbjct: 2545 DSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADI 2604 Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMI 4770 +TQ + A+ PL+ I EG A+F ++++ P + W G I +++I Sbjct: 2605 SITQKTRKPE--AIAPLKSIESVEGGQARFDVEMSAFPLPKVDWYHGGTKITHGGRYKII 2662 Query: 4771 H--EGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 +G+ V L+I + D+GT+ C AT G + L VK Sbjct: 2663 QSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVK 2707 Score = 119 bits (287), Expect = 5e-26 Identities = 81/310 (26%), Positives = 143/310 (46%), Gaps = 37/310 (11%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN--HTTL 323 P+ +K + ++EG ++ G P P V W +G+++ + H I TT + TL Sbjct: 27 PEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKV--QDDHRIKTTFDGERCTL 84 Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383 ++ +++ D G Y C+ T+ + Q + Sbjct: 85 KIMPSERDDEGEYK--------CVATN----------------------EVGQATITTEV 114 Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443 + E P+F + Q V EG RFD R+ G+P P+V WF N +I ++ +I ++ Sbjct: 115 LVKETLRKPEFKQKMQPLQVLEGDEVRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEI-ID 173 Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503 E ++L+I + LSD+ C+A +++G++ C + + KE+ AP+ + +N+ Sbjct: 174 EEDLYSLIIDDTRLSDADTYKCIATSEAGKST--CIVELSVKEKTSAPEVFGDTAPINIT 231 Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563 EG+ + L+ R G P P I W KD PI L T L + AK D+ Y+C Sbjct: 232 EGDELDLSVRVRGKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKC 291 Query: 564 TAQNVAGSTA 573 TA++ G+ + Sbjct: 292 TAKSEHGTAS 301 Score = 119 bits (286), Expect = 7e-26 Identities = 83/314 (26%), Positives = 141/314 (44%), Gaps = 32/314 (10%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+ QK + ++ EG + +F V++ G P P+V WFKN ++ N + EII + +L + Sbjct: 123 PEFKQKMQPLQVLEGDEVRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLII 182 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 +T+ SD+ Y CI TS + +S I + + + Sbjct: 183 DDTRLSDADTYK--------CIATS-------------EAGKSTCIVE---------LSV 212 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 EK AP+ ++TEG RV G+P PE+ W +D+ I+ + + Sbjct: 213 KEKTSAPEVFGDTAPINITEGDELDLSVRVRGKPKPEIKWTKDDKPIKKT-DRLTTTTKD 271 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVRE 504 L++++ DSG C A+++ G + + +NV + K + VAPKF + TL + E Sbjct: 272 DECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIME 331 Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 E L G P P W K P+ ++I D + L++ + D A Y+ Sbjct: 332 KETARLECTVTGEPAPTTEWLKGDQPLKETQRIKIERDKDSVVLEVRHVELDDEALYKVV 391 Query: 565 AQNVAGSTATRARL 578 A+N +G + A L Sbjct: 392 AKNESGVATSEAEL 405 Score = 113 bits (273), Expect = 2e-24 Identities = 112/516 (21%), Positives = 193/516 (37%), Gaps = 29/516 (5%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P F + + + A+ E + G P P W + PL E + + ++ + V L Sbjct: 318 PKFTKPLETLEIMEKETARLECTVTGEPAPTTEWLKGDQPLKETQRIKIERDKDS--VVL 375 Query: 132 LIKQIGPGDEGEYTCTARNQYGEAI--CSVYIQPEGXXXXXXXXXXXXXYRHVSET-VEH 188 ++ + DE Y A+N+ G A + + E ++ Sbjct: 376 EVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLEGDEIRLDA 435 Query: 189 KAYGTQGYTTEQSRQTQKVAYTNG---TDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245 + G T + + QKVA D D F + + L + T Sbjct: 436 RVGGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATND-T 494 Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 G++ + +I+ L V+P ++ L E D ++ ++G P+P V W K+ + Sbjct: 495 GKATAEAEIQIEELL--VAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKP 552 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365 L ++ I + + + +DSG Y A+N G T +++ + Sbjct: 553 LTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGV-----------NTRTFIVN 601 Query: 366 QRSQYITDTQQRETEER-IEISEKAL--APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422 ++ Q R I +++K AP+ + Q+ + EG C+ TG P P Sbjct: 602 VEVLFVAGISQVIGSIRFIVLAKKPAGEAPEITESLQEMEELEGNPVTLTCKFTGTPAPV 661 Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 WF +RD +KI ++ L I L D+ V RN G + R+ + Sbjct: 662 AEWFKASTPVRDGRRYKITTTDN-TTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRI 720 Query: 483 IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542 +V P F ++ + V EG+ L+ R VGTPTP + W + + Sbjct: 721 ---TALVRPDFTKKLKPVEVEEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEE 777 Query: 543 GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 G + TL I D Y+C A N G R L Sbjct: 778 GDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDL 813 Score = 113 bits (271), Expect = 4e-24 Identities = 77/262 (29%), Positives = 114/262 (43%), Gaps = 15/262 (5%) Query: 4543 IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602 + V WLK+ K + D K +G TL++ QD G Y+C N G A C A + Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728 Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG-DK 4661 V+ A K P I++PL + V E F +I G P P V WY G K Sbjct: 1729 VNEKAVK-------------PVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTK 1775 Query: 4662 LIKPSKYFQMSRTADE-YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720 LI+ + Y + + + +TL ++++ D G YKCVA N AG+ A L+VT A Sbjct: 1776 LIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPT 1835 Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780 + V GQ I P + W ++ + E+ ++I +GN L+I Sbjct: 1836 FVEDEVKDAVYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLII 1895 Query: 4781 GNTYEEDTGTFTCRATTAAGQV 4802 D+G + C A G V Sbjct: 1896 YKASLNDSGIYRCVAKNTHGSV 1917 Score = 112 bits (270), Expect = 6e-24 Identities = 117/521 (22%), Positives = 205/521 (39%), Gaps = 45/521 (8%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P F++ +N +G + + ++ G P P V W + + E ++ + +E+ SL Sbjct: 414 PFFKKTPQNVTVLEGDEIRLDARVGGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSL 473 Query: 132 LIKQIGP-----------GDEGEYTCTARNQYGEAICSV-YIQPEGXXXXXXXXXXXXXY 179 +I P D G+ T A Q E + + + + E Sbjct: 474 IIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLE 533 Query: 180 RHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV---DTFEYRLLREVSF 236 HV+ + + + T+ + + ++ + D D V D+ Y+ E Sbjct: 534 LHVTGKPKPEVHWTKD--NKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKC--EAKN 589 Query: 237 RESI-TKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRP 295 + + T+ ++ +V I + +G + +A+KP + Q +L GNP Sbjct: 590 KAGVNTRTFIVNVEVLFVAGISQVIGSIRFIVLAKKPAGEAPEITESLQEMEELEGNPVT 649 Query: 296 RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 F T +T D Y + + N +T + Sbjct: 650 LTCKFTG-------------TPAPVAEWFKASTPVRDGRRYKITTTD-NTTTLTIKETRL 695 Query: 356 ESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRV 415 + TE V + D ++E R+ I+ + P F K + +V EG+ R D RV Sbjct: 696 DDNTEYQVVIRN-----DIGSVKSETRVRITA-LVRPDFTKKLKPVEVEEGQEARLDVRV 749 Query: 416 TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETA 475 G P P V WF ++ D ++ + E ++ L+I D CVA N+ G+ Sbjct: 750 VGTPTPNVEWFCGTTKLTDTDRYE-FIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVT 808 Query: 476 FQCRLNVIEKEQVVAPKFV--ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533 CR ++ E++ P+ ER + + E E +V+N +G P P + W KDG PI Sbjct: 809 --CRGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQ 866 Query: 534 NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574 + L I G TL+I + DA Y C AQN G+++T Sbjct: 867 SSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSST 907 Score = 112 bits (270), Expect = 6e-24 Identities = 118/490 (24%), Positives = 191/490 (38%), Gaps = 44/490 (8%) Query: 95 LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154 +RGNP P V+W + + L + + M + + L + + P D G Y C A+N+ G Sbjct: 2149 IRGNPRPDVNWYKDGSFLQQTGR--MGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGT 2206 Query: 155 AICSVYIQPEGXXXXXXXXXXXXXYR-HVSE----TVEHKAYGTQGYTTEQSRQTQKVAY 209 A +V ++ E + + E T+ + G T R V Sbjct: 2207 ASRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHT 2266 Query: 210 TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA 269 N S + L + + G + I R + P Sbjct: 2267 DNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRK---DAIPTFV 2323 Query: 270 QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQ 329 + ++ E +D + V++ G PRP V ++K+ +++S +H+I+ + +L + N + Sbjct: 2324 VGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLR 2383 Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKA 389 D+G Y C++T+ L VE+ +E I + E+ Sbjct: 2384 PEDAGTYK--------CVITN-LLGVET---------------------SEAVIRVQERE 2413 Query: 390 LAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447 AP+F + VT EG + G+P P VTW + D + N L + Sbjct: 2414 HAPRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTW-MKDGNVISSSNGVSLRQRGES 2472 Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-IEKEQVVAPKFVERFSTLNVREGE 506 ++L+I VT DSG TC A + G+ + L V K + P F+ L VREG Sbjct: 2473 YSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGF 2532 Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566 L + V T +I W+KDG P DG TL A DA YQC Sbjct: 2533 EFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVT 2592 Query: 567 NVAGSTATRA 576 N G +++ A Sbjct: 2593 NKFGESSSSA 2602 Score = 111 bits (266), Expect = 2e-23 Identities = 85/318 (26%), Positives = 150/318 (47%), Gaps = 39/318 (12%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P I + N +++E + +F+VQ++GNP+PRV W+ +LI ++++ Sbjct: 1736 PVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKML---------- 1785 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 DSG++T ++ + +S V + + + ++ +E+ Sbjct: 1786 -----EDSGNHTFT-------LIVNDSQRHDSGVYKCVA------VNEAGKAISQATLEV 1827 Query: 386 SEKALAPQFVK--VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443 + + AP FV+ V V G+ + G P P+V W+ +D+++++ KI+ Sbjct: 1828 TGRPCAPTFVEDEVKDAVYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKII-- 1885 Query: 444 ESGN-HALMITNVTLSDSGVVTCVARNKSGETA--FQCRLNVIEKEQVVAPKFVERFSTL 500 GN + L+I +L+DSG+ CVA+N G + F R+ V K AP+FV + Sbjct: 1886 PKGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGK----APRFVSELRPV 1941 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 V EG V L + P W ++G P+ + ++ DG STL AK D Sbjct: 1942 EVFEGNEVSLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGT 2001 Query: 561 YQCTAQNVAGSTATRARL 578 Y C A+NV GS +++A+L Sbjct: 2002 YSCLAKNVFGSASSQAKL 2019 Score = 110 bits (265), Expect = 2e-23 Identities = 97/389 (24%), Positives = 160/389 (41%), Gaps = 26/389 (6%) Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485 ++ + +G P P + WY+++ ++ S +I LII + + DS ++ VA Sbjct: 1851 QEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVA 1910 Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545 +N G+ + ++ VE G+ P F + V V G V L K++ Sbjct: 1911 KNTHGSVSRTFDVRVEV---DGKA----PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF 1963 Query: 4546 YWLKNGKKVQPDIRNKILEEDGTY-TLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604 W +NG V+ D R + DG Y TL L A +D G Y C+A N G A A+ +V Sbjct: 1964 EWSRNGSPVRLDNRVQ-ASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVK 2022 Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664 K N P+ I ++D EG F G P V+W G++ I Sbjct: 2023 ------------KKGNR-PQPIGMIRDIEGYEGGQARFDVHFTGN--PKVEWLHGEEQII 2067 Query: 4665 PSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722 + +++S E Y+L + + ED G Y CVA N +G T+ A L V A Sbjct: 2068 HGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDKHIAPMFV 2127 Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782 I V G+ I +P + W ++G+ + +T + ++ L + Sbjct: 2128 EDDTGEPITVEAGKELNVIMNIRGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFK 2187 Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 +D G + C A G + + V+ Sbjct: 2188 AVPDDAGIYRCEAKNKLGTASRTVMVKVE 2216 Score = 106 bits (255), Expect = 4e-22 Identities = 119/524 (22%), Positives = 214/524 (40%), Gaps = 52/524 (9%) Query: 66 PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125 P + + P F + + +G + +++G PTP V W + + ++ ++ + Sbjct: 21 PDKGTIPEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKVQDDHRIKTTFDGE 80 Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET 185 + ++ + DEGEY C A N+ G+A + + + + V E Sbjct: 81 RCTLKIMPSE--RDDEGEYKCVATNEVGQATITTEVLVKETLRKPEFKQKMQPLQ-VLEG 137 Query: 186 VEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFE--YRLL-REVSFRESIT 241 E + + T KV + N T + F++ E Y L+ + ++ T Sbjct: 138 DE-----VRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADT 192 Query: 242 KRYVGESDVQISTEI-DRSLGP-VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299 + + S+ ST I + S+ S P++ + EG + V++ G P+P + W Sbjct: 193 YKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINITEGDELDLSVRVRGKPKPEIKW 252 Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359 K+ + + K + +TT T K D C++ L+ P Sbjct: 253 TKDDKPI---KKTDRLTT----------TTKDDE------------CVLV---LSDAKPE 284 Query: 360 ES--YVQDQRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVT 416 +S Y +S++ T +E + +E ++ K +AP+F K + ++ E + R +C VT Sbjct: 285 DSGRYKCTAKSEH--GTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKETARLECTVT 342 Query: 417 GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAF 476 G P P W D+ +++ KI + + L + +V L D + VA+N+SG Sbjct: 343 GEPAPTTEWLKGDQPLKETQRIKI-ERDKDSVVLEVRHVELDDEALYKVVAKNESGVATS 401 Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536 + L V E P F + + V EG+ + L+AR G P P + W K + Sbjct: 402 EAELLV--NEATEKPFFKKTPQNVTVLEGDEIRLDARVGGKPEPTVDWFKGDQKVAEEGR 459 Query: 537 LRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 I D G +L I AK D+ Y C A N G A + Sbjct: 460 FLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEI 503 Score = 106 bits (255), Expect = 4e-22 Identities = 141/651 (21%), Positives = 251/651 (38%), Gaps = 63/651 (9%) Query: 231 LREVSFRESITKRYVGESDV-QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL 289 ++E ++ + V +D+ + +E + + P +K + +++EG +A+ V++ Sbjct: 690 IKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEVEEGQEARLDVRV 749 Query: 290 SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349 G P P V WF +L + T R ++ DS YTL+ + Sbjct: 750 VGTPTPNVEWFCGTTKLTD-------------TDRYEFIEEGDS--YTLIIKT------- 787 Query: 350 SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVT--EGK 407 V ++Y +Q T + + ++++EK P+ + + + E + Sbjct: 788 ----TVRDDDDTYKCVASNQVGKVTCRGD----LKVTEKMFPPEITRPERTEKIVLLEKE 839 Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCV 466 + + G P P+V WF + + IR + ++ + G+ + L I D+G TC Sbjct: 840 ELVINVTILGNPRPDVKWFKDGKPIRQ--SSRLNIRPRGDTYTLNIHTTEPEDAGSYTCE 897 Query: 467 ARNKSGETAFQCRLNV-IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525 A+NK G ++ + + K + AP V + EGE L + G P P I W Sbjct: 898 AQNKMGTSSTTIDVQIEASKPKGEAPSLVSELQPQEISEGEDAKLECKVSGEPQPTIEWF 957 Query: 526 KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXX 585 KD P+ + +R DG STL I A D Y+C A N GST+ L Sbjct: 958 KDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPV 1017 Query: 586 XXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYI-PPGEEDRVYPPPQFIVPLK 644 Q P KV + E P P E V PQ ++ Sbjct: 1018 EEEKQ-----PEKPKVEKPEVEEPE----VEKPEVEEPVSGKPEVETPVGEVPQEVLAPV 1068 Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704 +V +E I E ++P G+ ++ L+ +++E + ++ + Sbjct: 1069 TVEVVETAPITLED-MKPTGEAPKVVDALQPLEALEGDEAKL---------VCKITGSPT 1118 Query: 705 DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPET--LQYIQQLEDYSKYQHQESI 762 + E+ V TK + + AT+ + PE + D+ + ++ Sbjct: 1119 PTVEWFKEKAKVVDVRRTK-MEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATL 1177 Query: 763 EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822 +P F L+ + E+ E A FE + T P VEW+ I S R + Sbjct: 1178 HINPVVKPDFKTKLKPM-EVTEESVAKFEVRSTGFPQP--EVEWFLGSTKIEDSGRFRVV 1234 Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLG 873 L I ++ +DAG+Y N+ G A S A ++V + +G Sbjct: 1235 SEQDRHELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKDCAPEFVG 1285 Score = 104 bits (250), Expect = 2e-21 Identities = 126/517 (24%), Positives = 213/517 (41%), Gaps = 68/517 (13%) Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290 +IE +PK P V+EL+ + EG+ A EC+V +P IE++ + + + + R Sbjct: 912 QIEASKPKGEAPSLVSELQ-PQEISEGEDAKLECKVSG--EPQPTIEWFKDDEPVTTDNR 968 Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350 +D +L I+ +D G+Y A N LG ++ + V K + E ++PE Sbjct: 969 VRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKP--VEEEKQPEK- 1025 Query: 2351 EKIRELESAEP-FKRPEIPEPVTR----QRPVFTQPLQNID--NIQEGQTAHFDCR-LIP 2402 K+ + E EP ++PE+ EPV+ + PV P + + ++ +TA + P Sbjct: 1026 PKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKP 1085 Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXX 2462 G+ V+ + + +E G + T+ +++ + V + R Sbjct: 1086 TGEAPKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVVDVRRTK-------- 1137 Query: 2463 XXXXXXXXXXXIQLETQHPE--GMKKIQKLEQPHERRSEEP--DREFEKPIFTQVLTGPS 2518 + + T PE GM K E + KP F L P Sbjct: 1138 --MEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHINPVVKPDFKTKLK-PM 1194 Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578 E+ E A +E R G P EW++ +++ RFR + L I+ V DA Sbjct: 1195 EVTEESVAKFEVR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDA 1252 Query: 2579 GLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGV 2638 G Y C N+AG ++ + LK + PE FV G Sbjct: 1253 GTYKCTLANQAGT-----------------------AYSRADLKVKEKDCAPE-FV--GD 1286 Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698 Q API +G+ + + AQ+ + PN+K W+K+G L G R Sbjct: 1287 QAAPIVVR---------QGEDIDIGAQITAKPKPNVK--WYKDGKPLRDGPRTTIRARDD 1335 Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 L + S + +D+G+Y C+ATN +G+A T +++E Sbjct: 1336 LYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372 Score = 103 bits (246), Expect = 5e-21 Identities = 99/430 (23%), Positives = 171/430 (39%), Gaps = 40/430 (9%) Query: 61 ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120 + A +P +P I E + + +G K G P PV W + P+ + +Y + Sbjct: 621 VLAKKPAGEAPEITESL-QEMEELEGNPVTLTCKFTGTPAPVAEWFKASTPVRDGRRYKI 679 Query: 121 RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR 180 + T +L IK+ D EY RN G ++ Sbjct: 680 TTTDNT--TTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEV 737 Query: 181 HVSE--TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE 238 + ++ + GT E T K+ T+ + D + + + + Sbjct: 738 EEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYK 797 Query: 239 SITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPR 296 + VG+ + ++ + PP+I + R K L E + V + GNPRP Sbjct: 798 CVASNQVGKVTCRGDLKVTEKM---FPPEITRPERTEKIVLLEKEELVINVTILGNPRPD 854 Query: 297 VTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356 V WFK+G+ + S++ I + TL + T+ D+G YT A+N G T+ + +E Sbjct: 855 VKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIE 914 Query: 357 SPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT 416 + + + E +SE L PQ +++EG+ + +C+V+ Sbjct: 915 A-----------------SKPKGEAPSLVSE--LQPQ--------EISEGEDAKLECKVS 947 Query: 417 GRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETA 475 G P P + WF +D + D +++ + G L I + TL D G CVA N+ G T+ Sbjct: 948 GEPQPTIEWFKDDEPVTTD--NRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTS 1005 Query: 476 FQCRLNVIEK 485 L V EK Sbjct: 1006 ATTELLVNEK 1015 Score = 103 bits (246), Expect = 5e-21 Identities = 64/193 (33%), Positives = 99/193 (51%), Gaps = 7/193 (3%) Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444 ++EKA+ P VK + V E +TRF+ ++ G P P V W+ ++ + +K+L + Sbjct: 1729 VNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKML-ED 1787 Query: 445 SGNH--ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER--FSTL 500 SGNH L++ + DSGV CVA N++G+ Q L V + AP FVE + Sbjct: 1788 SGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRP--CAPTFVEDEVKDAV 1845 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 VR G+ V L G PTP + W KD + + ++I G L I +A +D+ Sbjct: 1846 YVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGI 1905 Query: 561 YQCTAQNVAGSTA 573 Y+C A+N GS + Sbjct: 1906 YRCVAKNTHGSVS 1918 Score = 102 bits (244), Expect = 8e-21 Identities = 84/328 (25%), Positives = 142/328 (43%), Gaps = 38/328 (11%) Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308 DVQ+ E+ + G S P + + + + G D + ++SG P+P++ W K+ + L Sbjct: 1368 DVQV--EVPKPRG--SKPSLEAELKPVTVTAGEDTKLVCKISGKPQPKIDWMKDDKPLKP 1423 Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368 + ++ T++ T C++T +E E V + Sbjct: 1424 DKR--VLPTYDGET-----------------------CVLTFHKAVLEDEAEYKVVAKN- 1457 Query: 369 QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428 + T + ++EK AP+ K QD V GK F+ +V+G P PEV WF Sbjct: 1458 ----ELGSVSTSAELLVNEKGAAPKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKG 1513 Query: 429 DRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV--IEK 485 + + D I+ + + G L+I + DSGV CV N GET + +L V +E Sbjct: 1514 ESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEV 1573 Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGG 544 K E+ + V E + V ++ + G P ++ W KD P+ N +IH++G Sbjct: 1574 APKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGR 1633 Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGST 572 L + A DA Y+C + G+T Sbjct: 1634 MYYLTLTDASLDDAGHYRCESTTKLGTT 1661 Score = 98.7 bits (235), Expect = 1e-19 Identities = 54/198 (27%), Positives = 90/198 (45%), Gaps = 3/198 (1%) Query: 383 IEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440 + + +K +AP FV+ +T GK + G P P+V W+ D Sbjct: 2115 LNVKDKHIAPMFVEDDTGEPITVEAGKELNVIMNIRGNPRPDVNWY-KDGSFLQQTGRMG 2173 Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500 + + ++ L + D+G+ C A+NK G + + V E + P F+ + Sbjct: 2174 ISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVEELKGRGVPSFITGLFPV 2233 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 ++EG+ L R G P P ITW +D P+ + + +G S L++ K SDA Sbjct: 2234 QIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGL 2293 Query: 561 YQCTAQNVAGSTATRARL 578 Y+CTA N GST++ A + Sbjct: 2294 YKCTATNSQGSTSSSAEV 2311 Score = 97.9 bits (233), Expect = 2e-19 Identities = 111/462 (24%), Positives = 179/462 (38%), Gaps = 31/462 (6%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836 +S L EG++ EC V PT IEWF +++P+ + R ++ +D +L I Sbjct: 926 VSELQPQEISEGEDAKLECKVSGEPQPT--IEWFKDDEPVTTDNRVRADYDGKTSTLTIR 983 Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAE----E 2892 +D G Y C ATN GS + + L +K + + Q + K VE+ E E Sbjct: 984 DATLDDEGDYKCVATNELGSTSATTEL-LVNEKPVEEEKQPEKPKVEKPEVEEPEVEKPE 1042 Query: 2893 ARLAKGRRPSV--PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFN 2950 +P V P E P+ E + P+ E +VE + LE ++P + ++ Sbjct: 1043 VEEPVSGKPEVETPVGEVPQ-EVLAPVTVE--VVETAPITLE-DMKPTGEAPKVVDALQP 1098 Query: 2951 GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLI 3010 + LE G KL V+ ++ + + + + Y L Sbjct: 1099 LEALE-GDEAKLVCKITGSPTPTVEWFKEKAKVVDVRR---------TKMEYTDDVATLT 1148 Query: 3011 ERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEA 3070 T P+ +G+ K D + P+F T K + +++E +A +E Sbjct: 1149 IPTTRPED-KGMYKCVAKNDFGEASTSATLHINPVVKPDFKTKLKPM-EVTEESVAKFEV 1206 Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130 TG +EWF IE S R R V L I K D+GTY C N+ G Sbjct: 1207 R--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQAG 1264 Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190 A L+ K K P F ++ G+ + P++K WY +G+ Sbjct: 1265 TAYSRADLKV--KEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVK--WYKDGK 1320 Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 P+R R + + + D+G Y C A N G+ Sbjct: 1321 PLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGK 1362 Score = 95.1 bits (226), Expect = 1e-18 Identities = 120/514 (23%), Positives = 198/514 (38%), Gaps = 71/514 (13%) Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367 M P+ +R + V L + +G+ V+WF +GKPI+ R D Sbjct: 819 MFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDT 878 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427 L++ + PED+G YTC+A N++G + T+ D+ +E+ P G Sbjct: 879 YTLNIHTTEPEDAGSYTCEAQNKMGTSSTTI--------DVQIEASKPKG---------- 920 Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487 + ++ E ++P + + EG+ ECK+ + +EWFK+ +PV Sbjct: 921 ---EAPSLVSE---LQP---------QEISEGEDAKLECKVSG--EPQPTIEWFKDDEPV 963 Query: 1488 TIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547 T +R R +D L I D +D G Y C A N +G+ + L Sbjct: 964 TTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPVEEEKQP 1023 Query: 1548 NEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDA 1607 + +E+ +V E + V+E + P T + E+ + A ++ + Sbjct: 1024 EKPKVEKPEVEEPEVEKPE---VEEPVSGKPEVETPVG--EVPQEVLAPVTVEVVETAPI 1078 Query: 1608 TLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---- 1663 TL+ + KP + + AL + L D C+ + V Sbjct: 1079 TLE-----DMKPTGEAPKVVD-------ALQPLEALEGDEAKLVCKITGSPTPTVEWFKE 1126 Query: 1664 -SGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQD--EVITQA---------P 1711 + + V K Y + +P ED Y+ + D E T A P Sbjct: 1127 KAKVVDVRRTKMEYTDDVATLTIPTTRP-EDKGMYKCVAKNDFGEASTSATLHINPVVKP 1185 Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771 F +K + V E A FE R G P+ VEW IE S R + + L Sbjct: 1186 DFKTKLKPMEVTEESVAKFEVR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELI 1243 Query: 1772 MKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + V +D+GTY C N+ G A + + L V+ K Sbjct: 1244 ISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK 1277 Score = 94.3 bits (224), Expect = 2e-18 Identities = 60/225 (26%), Positives = 103/225 (45%), Gaps = 7/225 (3%) Query: 4410 PPIFTK--KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467 PP T+ + + + E E+ V G P P +KW+++ PI+ S I Sbjct: 821 PPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYT 880 Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 L I ED+ + A+N+ GT+ + ++ +E + +G PS Q ++ Sbjct: 881 LNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIEASKPKGEA----PSLVSELQPQEISE 936 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 G+ +L+ KV+G + W K+ + V D R + + T TL I +A D G Y+CV Sbjct: 937 GEDAKLECKVSGEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCV 996 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632 A N G E +V+ +++ +P+ K PE+ EP +K Sbjct: 997 ATNELGSTSATTELLVNEKPVEEEKQPE-KPKVEKPEVEEPEVEK 1040 Score = 91.9 bits (218), Expect = 1e-17 Identities = 75/318 (23%), Positives = 131/318 (41%), Gaps = 22/318 (6%) Query: 4376 KEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFD 4435 KE + T + + +Q+ + VE P +PP F ++ P +V E + + + Sbjct: 2482 KEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGFEFKLIFKVV 2541 Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 I+W ++ + + L + ++D+ + + N+ G + S Sbjct: 2542 TTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSS 2601 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555 A++ + +K R+ P +++ G R D +++ V W G K+ Sbjct: 2602 ADISITQKTRK-------PEAIAPLKSIESVEGGQARFDVEMSAFPLPKVDWYHGGTKIT 2654 Query: 4556 PDIRNKILEE-DG---TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611 R KI++ DG YTL+I DSG Y+C+A N G ++ V P Sbjct: 2655 HGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVKEPFI--A 2712 Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671 P+ + K AP + +GQ I+ S KI +P P + WYK K + SK + Sbjct: 2713 PEFEGKDITAP---------MVYKDGQDIKVSFKIKSRPKPIIAWYKDGKALTSSKRVTL 2763 Query: 4672 SRTADEYTLRISEAFPED 4689 + D Y L I +A ED Sbjct: 2764 TSRGDTYELIIKKATKED 2781 Score = 90.6 bits (215), Expect = 3e-17 Identities = 63/202 (31%), Positives = 101/202 (50%), Gaps = 12/202 (5%) Query: 379 TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438 ++ ++ + +K PQ + + +D + EG RFD TG P +V W + QI + Sbjct: 2015 SQAKLLVKKKGNRPQPIGMIRDIEGYEGGQARFDVHFTGNP--KVEWLHGEEQIIHGEKY 2072 Query: 439 KILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE-- 495 KI N ++L++ ++ D G TCVA N+SG+ LNV K++ +AP FVE Sbjct: 2073 KISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNV--KDKHIAPMFVEDD 2130 Query: 496 RFSTLNVREGEP--VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553 + V G+ V++N R G P P + W KDG + + I + + L + +A Sbjct: 2131 TGEPITVEAGKELNVIMNIR--GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKA 2188 Query: 554 KASDAAWYQCTAQNVAGSTATR 575 DA Y+C A+N G TA+R Sbjct: 2189 VPDDAGIYRCEAKNKLG-TASR 2209 Score = 90.6 bits (215), Expect = 3e-17 Identities = 73/300 (24%), Positives = 122/300 (40%), Gaps = 31/300 (10%) Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336 ++ G + + + GNPRP V W+K+G L T R+ + + DS Sbjct: 2137 VEAGKELNVIMNIRGNPRPDVNWYKDGSFL-------------QQTGRMGISSRWDSYRL 2183 Query: 337 TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396 T+ P+ +G E+ + T R ++E + P F+ Sbjct: 2184 TVFKAVPDD----AGIYRCEAKNK-----------LGTASRTVMVKVEELKGRGVPSFIT 2228 Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456 + EG CRV+G+P P +TWF ++ + D N + E AL + + Sbjct: 2229 GLFPVQIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHTD-NRVVASYEGSVSALELKEMK 2287 Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516 LSD+G+ C A N G T+ + + K+ + P FV E + L+ + G Sbjct: 2288 LSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI--PTFVVGLKETEGLESSDMRLDVKIGG 2345 Query: 517 TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 P P + + KD I+ + +I DG +L I + DA Y+C N+ G + A Sbjct: 2346 FPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEA 2405 Score = 90.2 bits (214), Expect = 4e-17 Identities = 95/382 (24%), Positives = 163/382 (42%), Gaps = 47/382 (12%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P+FT K V++ EGQ A + ++ T + +EWF + + R + Sbjct: 726 PDFTKKLKP-VEVEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRYEFIEEGDSYT 782 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I T D TY C A+N+ G+ L+ +K P T + E + + Sbjct: 783 LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK---MFPPEITRPERTEKIVLLEKE 839 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 V + +P ++W+ +G+P+R S+R+ L+I T+ D+G Y C A Sbjct: 840 ELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQ 899 Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287 NK G T TI+ V +E+ +P + + PS S P+ I+ Sbjct: 900 NKMGTSST--TID------VQIEASKP---------------KGEAPSLVSELQPQEIS- 935 Query: 3288 IQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYC 3347 EG+ A E ++ +P +EWF + + + +R R +D L I Sbjct: 936 --------EGEDAKLECKV--SGEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDA 985 Query: 3348 YEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRR 3407 ++ G+Y+CVATN+LG ST A + E + + + P + +EK + +E+ V + Sbjct: 986 TLDDEGDYKCVATNELG--STSATTELLVNEKPVEEEKQPE--KPKVEKPE-VEEPEVEK 1040 Query: 3408 KDTSVEEEKGKAPVFTVPLSNI 3429 + VEE P P+ + Sbjct: 1041 PE--VEEPVSGKPEVETPVGEV 1060 Score = 89.0 bits (211), Expect = 8e-17 Identities = 102/505 (20%), Positives = 195/505 (38%), Gaps = 51/505 (10%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD-VS 130 P F K + + + + K+ G P P V + + +V+ ++ + + GD S Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKIL---EDGDRCS 2376 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE-H 188 L+I + P D G Y C N G I+ E E E + Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREHAPRFDGTDLGQSVTAQEGFELN 2436 Query: 189 KAYGTQGY---TTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITK-RY 244 K + +G T + ++ +NG + ++ +E S + Sbjct: 2437 KTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGE-SYSLVIIKVTKEDSGNYTCQAVSS 2495 Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304 +G++ +++ PP + +++EG + + ++ ++ W K+G+ Sbjct: 2496 LGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGR 2555 Query: 305 RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364 E + TL +N D+G Y CIVT+ + S + Sbjct: 2556 AFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQ--------CIVTNKFGESSSSAD---- 2603 Query: 365 DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424 I I++K P+ + + + EG RFD ++ P P+V Sbjct: 2604 ------------------ISITQKTRKPEAIAPLKSIESVEGGQARFDVEMSAFPLPKVD 2645 Query: 425 WFINDRQIRDDYNHKILVNESGN---HALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481 W+ +I +KI+ + G+ + L+I ++ +DSG C+A N+ G T + L Sbjct: 2646 WYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLK 2705 Query: 482 VIEKEQVVAPKFVERFST--LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539 V KE +AP+F + T + ++G+ + ++ + P P I W KDG + + + + Sbjct: 2706 V--KEPFIAPEFEGKDITAPMVYKDGQDIKVSFKIKSRPKPIIAWYKDGKALTSSKRVTL 2763 Query: 540 HTDGGASTLDIPRAKASDAAWYQCT 564 + G L I +A D +CT Sbjct: 2764 TSRGDTYELIIKKATKEDV---ECT 2785 Score = 88.2 bits (209), Expect = 1e-16 Identities = 81/335 (24%), Positives = 134/335 (40%), Gaps = 39/335 (11%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDF--GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998 P ++EW+ ++E RF + D G L + D DSG+Y C +N GE T Sbjct: 1504 PTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTK 1563 Query: 2999 STVYCTS------KDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD------DDTGR 3046 + + + D ++ + P LE Q ++ S++ + PD DDT Sbjct: 1564 AKLQVDAVEVAPKTDKKLDEKEEPITV--LEH-QEVDMSVKVKGKYVPDKVLWFKDDTPV 1620 Query: 3047 PPEFTT--------VFKDIVDISEGQIAHYEA-------SLIPTGDQSMVIEWFYNGKTI 3091 T + + D S HY + I T + +EW + K I Sbjct: 1621 KTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPI 1680 Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF 3151 ++ + G+ L + D G Y C+ TNK G A L + K KP Sbjct: 1681 AKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANL--IVNEKAVKPVI 1738 Query: 3152 TTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG--FVVL 3209 + N++ +++ FE + +P ++ WYH + T K + D G L Sbjct: 1739 VKPLSNLQ-VEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTL 1795 Query: 3210 DIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244 + +Q HDSG Y C A N+ G+ ++AT+ G+ Sbjct: 1796 IVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830 Score = 84.6 bits (200), Expect = 2e-15 Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 10/197 (5%) Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096 G + D G PEFT + + + EG+ +A + G + +EW +G+ ++ HR Sbjct: 16 GFEASPDKGTIPEFTKKLQPVT-VREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHR 72 Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ 3156 I+T + L+I+ ++ D G Y C ATN+ GQA I+ E + K +KP F +Q Sbjct: 73 IKTTFDGERCTLKIMPSERDDEGEYKCVATNEVGQATITT--EVLVKETLRKPEFKQKMQ 130 Query: 3157 NIEGLKDGQSAHFECTVVPVD-DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQ 3215 ++ L +G F+ V +D P K+EW+ N + + R + + + L I T+ Sbjct: 131 PLQVL-EGDEVRFD---VRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTR 186 Query: 3216 NHDSGEYVCRAYNKYGE 3232 D+ Y C A ++ G+ Sbjct: 187 LSDADTYKCIATSEAGK 203 Score = 83.0 bits (196), Expect = 5e-15 Identities = 59/202 (29%), Positives = 92/202 (45%), Gaps = 12/202 (5%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 G+ P F + + V++ EG L + + EW NG + +R++ + Sbjct: 1929 GKAPRFVSELRP-VEVFEGNEVSLVCKL--SAEAKPTFEWSRNGSPVRLDNRVQASFDGR 1985 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 L+ L K D GTYSC A N +G A KL + K KG +P+ I++IEG + G Sbjct: 1986 YSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKL--LVKKKGNRPQPIGMIRDIEGYEGG 2043 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG--FVVLDIAYTQNHDSGEY 3222 Q A F+ V +P K+EW H + + H + K + G L + ++ D G Y Sbjct: 2044 Q-ARFD--VHFTGNP--KVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRY 2098 Query: 3223 VCRAYNKYGEDFTRATINCYGK 3244 C A N+ G+ A +N K Sbjct: 2099 TCVASNESGDATLHANLNVKDK 2120 Score = 81.8 bits (193), Expect = 1e-14 Identities = 62/237 (26%), Positives = 104/237 (43%), Gaps = 10/237 (4%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140 ++WF +GK I S R+ L I T+ D+G+Y+C A NK G + ++ ++ Sbjct: 855 VKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIE 914 Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 K KG+ P + +Q E + +G+ A EC V +P IEW+ + +P+ R++ Sbjct: 915 ASKPKGEAPSLVSELQPQE-ISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTDNRVRA 971 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260 D L I D G+Y C A N+ G T AT E QP+ K+ Sbjct: 972 DYDGKTSTLTIRDATLDDEGDYKCVATNELGS--TSATTELLVNEKPVEEEKQPEK-PKV 1028 Query: 3261 RELESLQGAQQQTPST--PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLK 3315 + E ++ + + P P + P+ T + +V + V P+ D+K Sbjct: 1029 EKPE-VEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMK 1084 Score = 81.4 bits (192), Expect = 2e-14 Identities = 79/270 (29%), Positives = 112/270 (41%), Gaps = 42/270 (15%) Query: 1171 EISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227 E SK K P V L P +SEG++ LEC++ G+P +EWF + VT +R + Sbjct: 914 EASKPKGEAPSLVSELQ-PQEISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTDNRVR 970 Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQ 1287 YD L I AT D G+Y A N LGS + + V E+ + + Q E+ + Sbjct: 971 ADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK-PVEEEKQPEKPKVE 1029 Query: 1288 IQLLEDAARRTKQVREDIT--------VMQAPQFSRALHNIETVEGTNVHLE-------- 1331 +E+ +V E ++ V + PQ A +E VE + LE Sbjct: 1030 KPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKPTGEA 1089 Query: 1332 ----CRLQPV---------------GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDL 1372 LQP+ G T VEWF + R + Y D L + Sbjct: 1090 PKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVVDVRRTKMEYTDDVATLTI 1149 Query: 1373 LSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 + PED G+Y C A N GEA TS L + Sbjct: 1150 PTTRPEDKGMYKCVAKNDFGEASTSATLHI 1179 Score = 81.4 bits (192), Expect = 2e-14 Identities = 86/325 (26%), Positives = 136/325 (41%), Gaps = 38/325 (11%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E + + P+ +PLQD+ ++ G+ A F Q++ PT VEW+K + R Sbjct: 1467 ELLVNEKGAAPKIEKPLQDV-KVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRF 1523 Query: 820 TSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV-AARSTVTADLGIPE 876 I + G L I + ED+G Y N +GE + A ++V A D + E Sbjct: 1524 MIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDE 1583 Query: 877 QRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIK---EGGFAHF---E 930 + I T VP+ + TP+K + K EG + + Sbjct: 1584 KEEPI--TVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTD 1641 Query: 931 ARLEPIG----DST-------------LRVEWLKDGRPVEASSRITTFFNFGYVALTIKS 973 A L+ G +ST ++VEWLKD +P+ + F+ G L +K Sbjct: 1642 ASLDDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKH 1701 Query: 974 VTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRT 1033 V D G Y C+ N +G AT ANL IV +K + P ++ + L+ + R Sbjct: 1702 VVQQDKGVYKCKVTNKLGSATCGANL-IVNEKAV-----KPVIVKPLSNLQVEEKSLTRF 1755 Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEG 1058 E ++ KPR + GT K++EG Sbjct: 1756 EVQIAGNPKPR-VAWYHGTTKLIEG 1779 Score = 79.4 bits (187), Expect = 7e-14 Identities = 55/181 (30%), Positives = 85/181 (46%), Gaps = 6/181 (3%) Query: 3053 VFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILG 3112 VF D I+ + + S+ G I+W + K I+ + R+ T VL + Sbjct: 221 VFGDTAPINITEGDELDLSVRVRGKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSD 280 Query: 3113 TKTTDSGTYSCRATNKWGQA--EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170 K DSG Y C A ++ G A E V +E K KG P+FT ++ +E + + ++A E Sbjct: 281 AKPEDSGRYKCTAKSEHGTASKEFDVNVEKA-KPKGVAPKFTKPLETLE-IMEKETARLE 338 Query: 3171 CTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230 CTV +P EW QP++ + RIK D VVL++ + + D Y A N+ Sbjct: 339 CTVT--GEPAPTTEWLKGDQPLKETQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNES 396 Query: 3231 G 3231 G Sbjct: 397 G 397 Score = 79.0 bits (186), Expect = 9e-14 Identities = 114/518 (22%), Positives = 199/518 (38%), Gaps = 65/518 (12%) Query: 1437 DESVTIK--PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF- 1493 D VT K P +TRP+ E ++ + + + + V+WFK+G+P+ R Sbjct: 812 DLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLN 871 Query: 1494 -RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGL 1552 RP D L+I ED+G YTC A N +GT S+T I Sbjct: 872 IRPRGDT--YTLNIHTTEPEDAGSYTCEAQNKMGT----------SSTTI---------- 909 Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612 +Q+ + K +V E+ Q EI EG+ A E ++ T +E Sbjct: 910 -DVQIEASKPKGEAPSLVSELQPQ-----------EISEGEDAKLECKVSGEPQPT--IE 955 Query: 1613 WYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672 W+ +++P+ + +R + L I +D G Y C A N LG + +V+ K Sbjct: 956 WFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK 1015 Query: 1673 KSIYLESQHEGALPRLNQLE-DTSKYQRHSAQDEVI----TQAPVFTMPMK-----DIRV 1722 +E + + P++ + E + + ++ ++ V + PV +P + + V Sbjct: 1016 P---VEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEV 1072 Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782 E E + P G+ V+ L+ +E G +++ + Sbjct: 1073 VETAPITLE-DMKPTGEAPKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVV 1131 Query: 1783 YTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQ 1842 R E + V + T + + + K D + + Sbjct: 1132 DVRRTKMEYTDDVATLT--------IPTTRPEDKGMYKCVAKNDFGEASTSATLHINPVV 1183 Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 P F T+L P +++E A +E R +P P VEW+ ++ R+R ++ Sbjct: 1184 KPDFKTKLK-PMEVTEESVAKFEVRSTGFPQP--EVEWFLGSTKIEDSGRFRVVSEQDRH 1240 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 L I V +D+G Y C N G A S L V+ K+ Sbjct: 1241 ELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKD 1278 Score = 78.2 bits (184), Expect = 2e-13 Identities = 74/286 (25%), Positives = 120/286 (41%), Gaps = 40/286 (13%) Query: 1965 KRAVQDDSFVVEK---PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021 K + D V EK P+ +P + ++ L +T + +P V+W+ +G+P++ Sbjct: 806 KVTCRGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIR 865 Query: 2022 QGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLD 2081 Q R L+I ED G+Y C+A N +G TSS +D + ++ Sbjct: 866 QSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG----TSSTTIDVQ-------IE 914 Query: 2082 EQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHL 2141 + K E P + E QP + + EG+ A EC+V +P Sbjct: 915 ASK-------PKGEAPSLVSELQP-------------QEISEGEDAKLECKVS--GEPQP 952 Query: 2142 TIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 TI+WF + + + +R R +D L I +D G Y C ATN+LG T L V Sbjct: 953 TIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLV 1012 Query: 2202 AGHRNIILDTQHPNGLEKIRQLEAQGHST-RIEVEEPKISPPRFVT 2246 + + + + P K+ + E + + EVEEP P T Sbjct: 1013 --NEKPVEEEKQPE-KPKVEKPEVEEPEVEKPEVEEPVSGKPEVET 1055 Score = 77.8 bits (183), Expect = 2e-13 Identities = 67/234 (28%), Positives = 102/234 (43%), Gaps = 24/234 (10%) Query: 3044 TGRP--PEFTT-VFKDIVDISEGQIAHYEASLIPT--GDQSMVIEWFYNGKTIEASHRIR 3098 TGRP P F KD V + GQ E SL+ T G + + W+ + K ++ S ++ Sbjct: 1828 TGRPCAPTFVEDEVKDAVYVRGGQ----EVSLMLTINGFPTPDVMWYKDDKELQESQLVK 1883 Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQ 3156 + M L I DSG Y C A N G V++E VD G+ PRF + ++ Sbjct: 1884 IIPKGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVE-VD---GKAPRFVSELR 1939 Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216 +E + +G C + P EW NG P+R R++ D + L + Sbjct: 1940 PVE-VFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKI 1996 Query: 3217 HDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQ 3270 D G Y C A N +G ++A + KG +P + IR++E +G Q Sbjct: 1997 EDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGMIRDIEGYEGGQ 2044 Score = 77.0 bits (181), Expect = 4e-13 Identities = 95/391 (24%), Positives = 150/391 (38%), Gaps = 78/391 (19%) Query: 936 IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995 +G+ V+W KDG+P+ SSR+ L I + DAG YTC A N +G ++T Sbjct: 848 LGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSST 907 Query: 996 SANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKI 1055 + D+ E+ P G + P + L+ +I Sbjct: 908 TI--------DVQIEASKPKG------------------------EAPSLVSELQ-PQEI 934 Query: 1056 VEGQSAHFEARV--EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113 EG+ A E +V EPQ T+EW+ + + +T+ NR++ +D L I +D Sbjct: 935 SEGEDAKLECKVSGEPQP----TIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDE 990 Query: 1114 GVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTR----HIEESKFVEPMY-- 1167 G Y VA N G + + V + + + EK +E+ + EP+ Sbjct: 991 GDYKCVATNELGSTSATTELLVNEKPVEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGK 1050 Query: 1168 -QIE----------------EISKSKPVFVQ---PLSNPPPVS---------EGKNIHLE 1198 ++E E+ ++ P+ ++ P P V EG L Sbjct: 1051 PEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKPTGEAPKVVDALQPLEALEGDEAKLV 1110 Query: 1199 CRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHL 1258 C++ G PT VEWF V R K Y L I D G Y A N Sbjct: 1111 CKIT--GSPTPTVEWFKEKAKVVDVRRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDF 1168 Query: 1259 GSAHTSAIVRV--IERSDIVTDTQNEQAIEQ 1287 G A TSA + + + + D T + + E+ Sbjct: 1169 GEASTSATLHINPVVKPDFKTKLKPMEVTEE 1199 Score = 74.9 bits (176), Expect = 1e-12 Identities = 102/485 (21%), Positives = 182/485 (37%), Gaps = 49/485 (10%) Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC--SVY 160 V W + P+ + ++ G +L++K + D+G Y C N+ G A C ++ Sbjct: 1671 VEWLKDDKPIAKDRHLKEAFHN--GVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728 Query: 161 IQPEGXXXXXXXXXXXXXYRHVSET-VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTD 219 + + S T E + G T K+ GT + + Sbjct: 1729 VNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLI--EGTIYKMLE 1786 Query: 220 DFKVDTFEYRLLREVSFRESITKRY-VGESDVQISTEIDRSLG-PVSPPKIAQKPRNSK- 276 D TF + + K V E+ IS G P +P + + +++ Sbjct: 1787 DSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDEVKDAVY 1846 Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336 ++ G + + ++G P P V W+K+ + L S +II N L + +DSG Y Sbjct: 1847 VRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIY 1906 Query: 337 TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396 C+ + + +V R + R+E+ KA P+FV Sbjct: 1907 R--------CVAKNTHGSVS--------------------RTFDVRVEVDGKA--PRFVS 1936 Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNV 455 + +V EG C+++ P W N +R D +++ + G ++ L N Sbjct: 1937 ELRPVEVFEGNEVSLVCKLSAEAKPTFEWSRNGSPVRLD--NRVQASFDGRYSTLKFLNA 1994 Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515 + D G +C+A+N G + Q +L V K++ P+ + + EG + Sbjct: 1995 KIEDQGTYSCLAKNVFGSASSQAKLLV--KKKGNRPQPIGMIRDIEGYEGGQARFDVHFT 2052 Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 G P++ W II + +I + G +L + K D Y C A N +G Sbjct: 2053 G--NPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDAT 2110 Query: 574 TRARL 578 A L Sbjct: 2111 LHANL 2115 Score = 74.1 bits (174), Expect = 2e-12 Identities = 111/454 (24%), Positives = 177/454 (38%), Gaps = 72/454 (15%) Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSLDITHTY 2839 N+ EGD I + V +PT ++WF ++ + R+ D SL I + Sbjct: 422 NVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAK 479 Query: 2840 EEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGR 2899 DSG+Y C+ATN DT GKA EA Q EE +A Sbjct: 480 PLDSGVYICQATN---------------------DT----GKATAEAEIQIEELLVA--- 511 Query: 2900 RPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSR 2959 PE+ A + L+E + LE V K P+ + W + K L + R Sbjct: 512 -----------PEFAEEEATQLTLIEDDDMTLELHVTGKPKPE--VHWTKDNKPLTEDDR 558 Query: 2960 FKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGT 3019 + +D++ V DSG Y C+A NK G ++ + + + L + Sbjct: 559 IIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAG---VNTRTFIVNVEVLFVAGI----S 611 Query: 3020 EGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQS 3079 + + I+ + L K+P G PE T +++ ++ EG TG + Sbjct: 612 QVIGSIRFI--VLAKKP-------AGEAPEITESLQEMEEL-EGNPVTLTCKF--TGTPA 659 Query: 3080 MVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139 V EWF + R + L I T+ D+ Y N G SVK E Sbjct: 660 PVAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG----SVKSE 715 Query: 3140 C-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198 V + +P FT ++ +E +++GQ A + VV P+ +EW+ + + R Sbjct: 716 TRVRITALVRPDFTKKLKPVE-VEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRY 772 Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 + + + L I T D Y C A N+ G+ Sbjct: 773 EFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGK 806 Score = 74.1 bits (174), Expect = 2e-12 Identities = 100/418 (23%), Positives = 162/418 (38%), Gaps = 42/418 (10%) Query: 3684 EITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 ++ IE KP P E++ ++ EG +C+V G+P I+WF + P T Sbjct: 910 DVQIEASKPKGEAPSLVSELQPQ-EISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTD 966 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801 +RV D L I D G+Y C ATN+ GS + T ++ + K V E + P+ Sbjct: 967 NRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKP--VEEEKQPE 1024 Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861 EK E+E + EEP+ P ++++ E + V VE E + Sbjct: 1025 KPKVEK-PEVEEPEVEKPEVEEPVSGKP-----EVETPVGEVPQEVLAPVTVEVVETAPI 1078 Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICR-------AVNDFGEDF 3914 +E + P+G + V +L L D + +C+ V F E Sbjct: 1079 TLE-----DMKPTGEAPKVV-----DALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKA 1128 Query: 3915 TKATISCKKL--PDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQP 3972 + K+ D + +P R E + K E T L+ ++ Sbjct: 1129 KVVDVRRTKMEYTDDVATLTIP--TTRPEDKGMYKCVAKNDFGEA-STSATLH-INPVVK 1184 Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P F T+++ + E KFE + G P +VEWF + RF + + Sbjct: 1185 PDFKTKLKPM-EVTEESVAKFE--VRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHE 1241 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK---PGIVYDSQLPKHMKSIEKI 4087 + V +D+G Y C N G ++A +K K P V D P ++ E I Sbjct: 1242 LIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKDCAPEFVGDQAAPIVVRQGEDI 1299 Score = 72.5 bits (170), Expect = 8e-12 Identities = 71/304 (23%), Positives = 129/304 (42%), Gaps = 37/304 (12%) Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130 + I G + W +G I +S+ + L I+ DSG Y+C+A + G Sbjct: 2438 TFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLG 2497 Query: 3131 QAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189 +A S L+ K K + P F + + ++ +++G F+ V D KIEW +G Sbjct: 2498 KASQSFDLKVEAPKVKEEPPSFLSELPPLQ-VREG--FEFKLIFKVVTTKDSKIEWRKDG 2554 Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYL 3249 + + D + L D+G Y C NK+GE + A I+ + Sbjct: 2555 RAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADIS------ITQ 2608 Query: 3250 ESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPV 3309 ++ +P+++A ++ +ES++G Q + SA P + TK+ G +++ Sbjct: 2609 KTRKPEAIAPLKSIESVEGGQARFDVEMSAFPLPKVDWYHGGTKITHGG----RYKIIQS 2664 Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTK 3369 D D V + ++I + Y +SG Y+C+ATN+ G + K Sbjct: 2665 TDGDRPV--------------------YTLIIESLKY---TDSGTYKCIATNEGGVTTIK 2701 Query: 3370 ANLK 3373 ++LK Sbjct: 2702 SDLK 2705 Score = 72.1 bits (169), Expect = 1e-11 Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 37/197 (18%) Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781 +G+P + WF +G+P SR++ L+I DAG YTC A NK G+++T Sbjct: 848 LGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSST 907 Query: 3782 TAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841 T D+ +E+ P+G + + EL+ P+E + Sbjct: 908 TI--------DVQIEASKPKGEAPSLVSELQ-------PQE------------------I 934 Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGE 3901 E E + EC+V +P+ IEW+++ + + + +R R YD +L I +D G+ Sbjct: 935 SEGEDAKLECKV--SGEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGD 992 Query: 3902 YICRAVNDFGEDFTKAT 3918 Y C A N+ G T AT Sbjct: 993 YKCVATNELGS--TSAT 1007 Score = 71.3 bits (167), Expect = 2e-11 Identities = 43/115 (37%), Positives = 61/115 (53%), Gaps = 5/115 (4%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P+F K ++ V EG + L+A + PT VEW +G VQ HR KTT+D L Sbjct: 27 PEFTKKLQPVTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092 I+ + +D G Y C ATN VG+A T+ V V K L +Q+++ +Q LE Sbjct: 85 KIMPSERDDEGEYKCVATNEVGQATITTEVLV--KETLRKPEF-KQKMQPLQVLE 136 Score = 70.5 bits (165), Expect = 3e-11 Identities = 46/159 (28%), Positives = 70/159 (44%), Gaps = 5/159 (3%) Query: 422 EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481 +V W +D+ I D + K + +G L++ +V D GV C NK G C N Sbjct: 1670 KVEWLKDDKPIAKDRHLKEAFH-NGVCTLILKHVVQQDKGVYKCKVTNKLGSAT--CGAN 1726 Query: 482 VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541 +I E+ V P V+ S L V E + G P PR+ W +I ++ Sbjct: 1727 LIVNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKMLE 1786 Query: 542 DGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 D G TL + ++ D+ Y+C A N AG ++A L Sbjct: 1787 DSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATL 1825 Score = 68.9 bits (161), Expect = 9e-11 Identities = 95/441 (21%), Positives = 170/441 (38%), Gaps = 70/441 (15%) Query: 1803 QSKASLQLESQH----ESALQKIQQLEDSSRYQRREDVEVAVNQAPR--FITQLNGPTKL 1856 + K S+ LE +H + AL K+ +S + E+ VN+A F + + Sbjct: 368 RDKDSVVLEVRHVELDDEALYKVVAKNESG--VATSEAELLVNEATEKPFFKKTPQNVTV 425 Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYRTSNDFG-FAALDILTVYGEDS 1914 EG + R+ P+P V+W+ KV + G ++ G +L I DS Sbjct: 426 LEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDS 483 Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974 G Y C+A N+ G+A + + + E L ++ E+++ ++DD Sbjct: 484 GVYICQATNDTGKATAEAEIQI------------EELLVAPEFAEEEATQLTLIEDDDMT 531 Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034 +E GK P V W + +P+ + R + Sbjct: 532 LELHVTGK------------------------PKPEVHWTKDNKPLTEDDRIIIDHKGDS 567 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094 +DI+ D+GTY C+A N G T V V+ L++ + Q + I+ + Sbjct: 568 CIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEV---LFVAGI-SQVIGSIRFIVLA 623 Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154 ++P G+ P +L +E L EG+ C+ P +WF +R Sbjct: 624 KKP-------AGEAPEITESLQEMEEL-EGNPVTLTCKF--TGTPAPVAEWFKASTPVRD 673 Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214 G RY+ T L I T +D+ Y N +G + +++ P Sbjct: 674 GRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITA-------LVRP 726 Query: 2215 NGLEKIRQLEA-QGHSTRIEV 2234 + +K++ +E +G R++V Sbjct: 727 DFTKKLKPVEVEEGQEARLDV 747 Score = 68.1 bits (159), Expect = 2e-10 Identities = 83/366 (22%), Positives = 141/366 (38%), Gaps = 68/366 (18%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P+ +++W+++ P++ R+ +D L ED Y A NELG TS Sbjct: 1406 GKPQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTS 1465 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857 + L V K A KI+ + +DV+V + F TQ++G Sbjct: 1466 AELLVNEK----------GAAPKIE--------KPLQDVKVDAGKKATFNTQVSG----- 1502 Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF--GFAALDILTVYGEDSG 1915 P VEW+ +++ R+ +D G L I EDSG Sbjct: 1503 ---------------TPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSG 1547 Query: 1916 EYTCKAINNLGQAVSSIRLNVQSKESIIR-DSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974 Y C N++G+ + +L V + E + D + + E I LE +V Sbjct: 1548 VYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYV 1607 Query: 1975 VEKPQFGK---PIKNAEV----TEGHPVHLEATLTPVNDP-------------------- 2007 +K + K P+K +EG +L T ++D Sbjct: 1608 PDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLI 1667 Query: 2008 TMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067 ++VEW + +P+ + K + G L + + +D G Y CK TN +G A +++ Sbjct: 1668 IVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANL 1727 Query: 2068 KVDAKS 2073 V+ K+ Sbjct: 1728 IVNEKA 1733 Score = 67.7 bits (158), Expect = 2e-10 Identities = 65/255 (25%), Positives = 104/255 (40%), Gaps = 31/255 (12%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI--FRFGYI 694 P+ PL+ V G K F T++ G PT ++EW K +E RF I + G Sbjct: 1477 PKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVF 1534 Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV----TPRATIERTSQHPETLQYIQQL 750 L + +DSG Y C + G +TKA L V T ++ + E + ++ Sbjct: 1535 QLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQ 1594 Query: 751 E-DYS-----KYQHQESI--EEQTSQRPQFIRPLQDLGEL--------QEGRNAHFEAQL 794 E D S KY + + ++ T + R + G + H+ + Sbjct: 1595 EVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCES 1654 Query: 795 TPVSDPT-------MRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847 T T ++VEW KD +PI + F+ G +L + H+ +D G Y + Sbjct: 1655 TTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKV 1714 Query: 848 VNKLGEAISTASIRV 862 NKLG A A++ V Sbjct: 1715 TNKLGSATCGANLIV 1729 Score = 66.9 bits (156), Expect = 4e-10 Identities = 56/261 (21%), Positives = 106/261 (40%), Gaps = 18/261 (6%) Query: 4261 PETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGD----KVTSNTVAK 4316 P EW + + + Y ++E ++ +I ++ +R+ Y KVT K Sbjct: 755 PNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLK 814 Query: 4317 SMAQRYEDNL---DQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVV 4373 + + + ++TE++ ++ V + +P K+ +Q Sbjct: 815 VTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRP 874 Query: 4374 GDKEITRKITSTE-------TTEIEHKAQTQERVVEGPVKPSKP----PIFTKKMQPCRV 4422 T I +TE T E ++K T ++ ++ SKP P ++QP + Sbjct: 875 RGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIEASKPKGEAPSLVSELQPQEI 934 Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFA 4482 E E A+ E + GEP P I+W++++ P+ + S L IR ++D + Sbjct: 935 SEGEDAKLECKVSGEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYK 994 Query: 4483 AVAENRGGTAKCSANLVVEEK 4503 VA N G+ + L+V EK Sbjct: 995 CVATNELGSTSATTELLVNEK 1015 Score = 66.9 bits (156), Expect = 4e-10 Identities = 52/196 (26%), Positives = 84/196 (42%), Gaps = 9/196 (4%) Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103 TG P+ + + + EG A + TG + +EWF + R + Y Sbjct: 1086 TGEAPKVVDALQPL-EALEGDEAKLVCKI--TGSPTPTVEWFKEKAKVVDVRRTKMEYTD 1142 Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 + L I T+ D G Y C A N +G+A S L + KP F T ++ +E + + Sbjct: 1143 DVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHI---NPVVKPDFKTKLKPME-VTE 1198 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 A FE V P ++EW+ + S R + VS+ L I+ + D+G Y Sbjct: 1199 ESVAKFE--VRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYK 1256 Query: 3224 CRAYNKYGEDFTRATI 3239 C N+ G ++RA + Sbjct: 1257 CTLANQAGTAYSRADL 1272 Score = 66.5 bits (155), Expect = 5e-10 Identities = 64/283 (22%), Positives = 125/283 (44%), Gaps = 47/283 (16%) Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297 K+ PP +T T + + V + +P ++++ +GK ++ ++R +I Sbjct: 818 KMFPPE-ITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRG 876 Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELE 2357 +L+I PEDAG Y+ +A N +G ++ I + + E+ +P+G Sbjct: 877 DTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQI--------EASKPKG-------- 920 Query: 2358 SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK 2417 E P V+ +P I EG+ A +C++ G+P +EWF++++ Sbjct: 921 --------EAPSLVSELQP---------QEISEGEDAKLECKV--SGEPQPTIEWFKDDE 961 Query: 2418 LIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE 2477 + +R+ +D ++TI +DEG Y C A+N LG L Sbjct: 962 PVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTEL---------LV 1012 Query: 2478 TQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSEL 2520 + P +++ ++ E+P + E + E EKP + ++G E+ Sbjct: 1013 NEKP--VEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGKPEV 1053 Score = 66.1 bits (154), Expect = 7e-10 Identities = 80/377 (21%), Positives = 149/377 (39%), Gaps = 24/377 (6%) Query: 1837 EVAVNQ---APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893 E+ VN+ AP+ L K+ G+ A + ++ P P VEW+ +++ R+ Sbjct: 1467 ELLVNEKGAAPKIEKPLQD-VKVDAGKKATFNTQVSGTPTPE--VEWFKGESIVEDKGRF 1523 Query: 1894 RTSNDF--GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR-DSQHES 1950 +D G L I EDSG Y C N++G+ + +L V + E + D + + Sbjct: 1524 MIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDE 1583 Query: 1951 ALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMR 2010 E I LE +V +K + K + +H E + + Sbjct: 1584 KEEPITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDAS 1643 Query: 2011 VEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK-- 2068 ++ + R + + TT + + + + + A V T +K Sbjct: 1644 LDDAGHYR-CESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHV 1702 Query: 2069 VDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAH 2128 V G+Y + K +L + + +PV + L++L+ ++E Sbjct: 1703 VQQDKGVY-------KCKVTNKLGSATCGANLIVNEKAVKPVIVKPLSNLQ-VEEKSLTR 1754 Query: 2129 FECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKA 2186 FE ++ +P + W+H K+ G Y+ D G ++ ++ DSG Y C A Sbjct: 1755 FEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVA 1812 Query: 2187 TNKLGEAVNTCTLKVAG 2203 N+ G+A++ TL+V G Sbjct: 1813 VNEAGKAISQATLEVTG 1829 Score = 65.7 bits (153), Expect = 9e-10 Identities = 51/189 (26%), Positives = 79/189 (41%), Gaps = 12/189 (6%) Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106 PP F + + + EG ++ T D IEW +G+ + + Sbjct: 2516 PPSFLSELPPL-QVREGFEFKLIFKVVTTKDSK--IEWRKDGRAFTPGGNSEFSFDGRNI 2572 Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166 L D+G Y C TNK+G++ S + K++ KP +++IE ++ GQ Sbjct: 2573 TLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQKTR--KPEAIAPLKSIESVEGGQ- 2629 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK----TVSDFGFVVLDIAYTQNHDSGEY 3222 A F+ + P K++WYH G + H R K T D L I + DSG Y Sbjct: 2630 ARFDVEMSAFPLP--KVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTY 2687 Query: 3223 VCRAYNKYG 3231 C A N+ G Sbjct: 2688 KCIATNEGG 2696 Score = 64.5 bits (150), Expect = 2e-09 Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 3/139 (2%) Query: 1287 QIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEW 1346 Q+ + D + R IT + P F++ L +E EG L+ R+ VG T VEW Sbjct: 702 QVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEVEEGQEARLDVRV--VGTPTPNVEW 759 Query: 1347 FCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406 FC + R+ E D L + + +D Y C A+NQ+G+ L+V +K Sbjct: 760 FCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKV-TEK 818 Query: 1407 DLILESQHPSGLEKIQYLE 1425 E P EKI LE Sbjct: 819 MFPPEITRPERTEKIVLLE 837 Score = 64.5 bits (150), Expect = 2e-09 Identities = 101/382 (26%), Positives = 153/382 (40%), Gaps = 39/382 (10%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF--GI 3339 PK +QDV K+ G+ A F ++ P+ VEWF + R+ D G+ Sbjct: 1477 PKIEKPLQDV-KVDAGKKATFNTQVSGTPTPE--VEWFKGESIVEDKGRFMIIDDAKEGV 1533 Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQT 3399 L I E+SG Y+CV N +G TKA L+ + E + E + L+ Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEH 1593 Query: 3400 LE-DSMVRRKDTSVEEE----KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454 E D V+ K V ++ K PV T I + EG + LT TD Sbjct: 1594 QEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHS--EGRMYY----LTLTDASLDDA 1647 Query: 3455 EWYWNGKSLKAGSRFRTFCDFGFVILE-ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 Y + K G+ TF V +E + P +L A++N V T +K Sbjct: 1648 GHYRCESTTKLGTTISTFLII--VKVEWLKDDKPIAKDRHLKEAFHN---GVCTLILK-- 1700 Query: 3514 GKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENS 3573 +++ Q KG+ K+ G S T E P S+L + E S Sbjct: 1701 ---HVV---QQDKGVYKC--KVTNKLG-SATCGANLIVNEKAVKPVIVKPLSNLQVEEKS 1751 Query: 3574 SAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG---FVILEIGGVYQRDAGLY 3630 FE ++ + RV W+H L+ G+ K + D G F ++ + + D+G+Y Sbjct: 1752 LTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLI-VNDSQRHDSGVY 1808 Query: 3631 TCKATNRHGEATVSCKLQVKGR 3652 C A N G+A L+V GR Sbjct: 1809 KCVAVNEAGKAISQATLEVTGR 1830 Score = 64.1 bits (149), Expect = 3e-09 Identities = 39/118 (33%), Positives = 61/118 (51%), Gaps = 6/118 (5%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P F +L P + EG+ + R++ P P VEW +G+ +Q HR +T+ D Sbjct: 27 PEFTKKLQ-PVTVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCT 83 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 L I+ +D GEY C A N +GQA +I V KE+ +R + + ++ +Q LE D Sbjct: 84 LKIMPSERDDEGEYKCVATNEVGQA--TITTEVLVKET-LRKPEFKQKMQPLQVLEGD 138 Score = 64.1 bits (149), Expect = 3e-09 Identities = 78/339 (23%), Positives = 136/339 (40%), Gaps = 25/339 (7%) Query: 1477 KVEWFKNGQPVTIGHRFRPIHDF--GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 +VEWFK V RF I D G L I D EDSG+Y C N +G + +L Sbjct: 1507 EVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKL 1566 Query: 1535 TCRSTTDIVRSTQN-EAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQ 1593 + ++ + + E I VLE + + + + V+ + Sbjct: 1567 QVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTR 1626 Query: 1594 RAHFERRL--IPVSDATLK-VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTY 1650 + H E R+ + ++DA+L Y K G+ + F+ + + L +D Sbjct: 1627 KIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTIST-----FLIIVKVEWLKDDKPIA 1681 Query: 1651 TCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPR--LNQLEDTSKYQRHSAQDEVIT 1708 R + EA +G+ + K ++ Q +G N+L + ++ + Sbjct: 1682 KDRHLK---EAFHNGVCTLILK---HVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAVK 1735 Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 PV P+ +++V E FE ++ G+PK RV W + + D G Sbjct: 1736 --PVIVKPLSNLQVEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791 Query: 1769 ALNMKYVNPE--DSGTYTCRAINELGEAVTSSTLFVQSK 1805 + + + DSG Y C A+NE G+A++ +TL V + Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830 Score = 63.7 bits (148), Expect = 3e-09 Identities = 63/278 (22%), Positives = 119/278 (42%), Gaps = 14/278 (5%) Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102 +T R PEF + + + EG ++ + G + +EWF N I+ R + Sbjct: 118 ETLRKPEFKQKMQPL-QVLEGDEVRFDVRI--DGKPTPKVEWFKNRTKIDNEGRFEIIDE 174 Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162 + L I T+ +D+ TY C AT++ G++ V+L +K+ + T NI Sbjct: 175 EDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINIT--- 231 Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222 + + +V P +I+W + +P++ + R+ T + VL ++ + DSG Y Sbjct: 232 --EGDELDLSVRVRGKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRY 289 Query: 3223 VCRAYNKYGEDFTRATINC--YGKGGVYLESLQPDSLAKIRELESLQ----GAQQQTPST 3276 C A +++G +N GV + +P +I E E+ + + P+T Sbjct: 290 KCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKETARLECTVTGEPAPTT 349 Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314 + + + + Q + + S E R V +DD L Sbjct: 350 EWLKGDQPLKETQRIKIERDKDSVVLEVRHVELDDEAL 387 Score = 63.7 bits (148), Expect = 3e-09 Identities = 74/277 (26%), Positives = 117/277 (42%), Gaps = 39/277 (14%) Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474 EKG AP PL +++ + G+ A F +++ T P +VEW+ ++ RF D Sbjct: 1472 EKGAAPKIEKPLQDVK-VDAGKKATFNTQVSGTPTP--EVEWFKGESIVEDKGRFMIIDD 1528 Query: 3475 F--GFVILEISPTYPEDSGEYLCRAYNNYG----------EAVTTA---SMKVQGKRN-- 3517 G L I PEDSG Y C +N+ G +AV A K+ K Sbjct: 1529 AKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPI 1588 Query: 3518 IILESQ---LPKGMEGTI--DKIAALEGYSGTVDTLTPEAES-GNPPEFTTTPSDLILSE 3571 +LE Q + ++G DK+ + + T + S G T T + L Sbjct: 1589 TVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASL---- 1644 Query: 3572 NSSAHFECRLIPVNDSSM-------RVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQ 3624 + + H+ C +++ +VEW + KP+ +K G L + V Q Sbjct: 1645 DDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQ 1704 Query: 3625 RDAGLYTCKATNRHGEATVSCKLQV--KGRQGIILEP 3659 +D G+Y CK TN+ G AT L V K + +I++P Sbjct: 1705 QDKGVYKCKVTNKLGSATCGANLIVNEKAVKPVIVKP 1741 Score = 63.7 bits (148), Expect = 3e-09 Identities = 70/305 (22%), Positives = 120/305 (39%), Gaps = 34/305 (11%) Query: 278 QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337 QEG + + G PRP VTW K+G +I++ N +LR R +S S Sbjct: 2430 QEGFELNKTFIIRGKPRPTVTWMKDGN---------VISSSNGVSLRQRG--ESYSLVII 2478 Query: 338 LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397 + + +G ++ ++S+ D + E ++ E+ P F+ Sbjct: 2479 KVTKEDSGNYTCQAVSSLGKASQSF----------DLKV----EAPKVKEEP--PSFLSE 2522 Query: 398 CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457 V EG + +V ++ W + R N + + N L N TL Sbjct: 2523 LPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSF-DGRNITLAFKNATL 2581 Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517 D+G C+ NK GE++ +++ +K + P+ + ++ EG + Sbjct: 2582 KDAGRYQCIVTNKFGESSSSADISITQKTR--KPEAIAPLKSIESVEGGQARFDVEMSAF 2639 Query: 518 PTPRITWQKDGVPIIPNPELRI--HTDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 P P++ W G I +I TDG TL I K +D+ Y+C A N G T Sbjct: 2640 PLPKVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTT 2699 Query: 574 TRARL 578 ++ L Sbjct: 2700 IKSDL 2704 Score = 63.3 bits (147), Expect = 5e-09 Identities = 62/259 (23%), Positives = 102/259 (39%), Gaps = 31/259 (11%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF--GY 1767 AP P++D++V + A F ++ G P VEW + +E R + D G Sbjct: 1476 APKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533 Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-----KASLQLESQHES-ALQKI 1821 L ++ PEDSG Y C N++GE T + L V + K +L+ + E + + Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEH 1593 Query: 1822 QQLEDSSRYQR----------REDVEVAVNQAPRFITQ----LNGPTKLSEGQSAHYECR 1867 Q+++ S + + ++D V N + ++ T S + HY C Sbjct: 1594 QEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCE 1653 Query: 1868 IEPYPDPN-------MRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920 ++VEW + K + + + G L + V +D G Y CK Sbjct: 1654 STTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCK 1713 Query: 1921 AINNLGQAVSSIRLNVQSK 1939 N LG A L V K Sbjct: 1714 VTNKLGSATCGANLIVNEK 1732 Score = 63.3 bits (147), Expect = 5e-09 Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 7/210 (3%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--L 4468 P K +Q +V ++A F + G P P ++W++ +++ F I + + + L Sbjct: 1477 PKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQL 1536 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528 +I EDS V+ V N G + A L V+ + + + V Sbjct: 1537 VIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPK---TDKKLDEKEEPITVLEH 1593 Query: 4529 QLVRLDTKVTGTK-PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 Q V + KV G P V W K+ V+ + KI E Y L + +A D+G Y C Sbjct: 1594 QEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCE 1653 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTK 4617 + G +V + KD KP K Sbjct: 1654 STTKLGTTISTFLIIVKVEWLKD-DKPIAK 1682 Score = 63.3 bits (147), Expect = 5e-09 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 3/109 (2%) Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356 RT VR ++ +AP+F L +E EG V L C+L T EW NG P++ Sbjct: 1919 RTFDVRVEVDG-KAPRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLD 1975 Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 +R + +++ Y L L+ ED G Y+C A N G A + L V K Sbjct: 1976 NRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK 2024 Score = 62.9 bits (146), Expect = 6e-09 Identities = 87/360 (24%), Positives = 139/360 (38%), Gaps = 77/360 (21%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P FT+ LQ + ++EG+ D R+ G PT VEW + + ++D RI T D + Sbjct: 27 PEFTKKLQPV-TVREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHRIKTTFDGERCT 83 Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495 + I +DEG Y C A+N +G+ ++ + PE +K+Q L Sbjct: 84 LKIMPSERDDEGEYKCVATNEVGQ------ATITTEVLVKETLRKPEFKQKMQPL----- 132 Query: 2496 RRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555 QVL G ++ R+ G P+ + EW+ N ++ Sbjct: 133 ----------------QVLEG-------DEVRFDVRI--DGKPTPKVEWFKNRTKIDNEG 167 Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPES 2615 RF + +L I+ +DA Y C A + AG +S Sbjct: 168 RFEIIDEEDLYSLIIDDTRLSDADTYKCIATSEAG-----------------------KS 204 Query: 2616 WEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLK 2675 ++L PE+F DT API + EG L+ V R P + Sbjct: 205 TCIVELSVKEKTSAPEVFGDT----API---------NITEGDE--LDLSVRVRGKPKPE 249 Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 I+W K+ + RL +T L ++ + +DSG Y C A + G A + +E Sbjct: 250 IKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVE 309 Score = 62.9 bits (146), Expect = 6e-09 Identities = 85/380 (22%), Positives = 141/380 (37%), Gaps = 26/380 (6%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P + L+ EG E ++ G+P IEW K+ + + +R + + +L Sbjct: 923 PSLVSELQPQEISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTL 980 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756 + + D G+Y C A + G L V + E + PE + +++ E Sbjct: 981 TIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPVEEE--KQPEKPK-VEKPEVEEPE 1037 Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816 + +EE S +P+ P+ GE+ + A ++ + T+ +D +P + Sbjct: 1038 VEKPEVEEPVSGKPEVETPV---GEVPQEVLAPVTVEVVETAPITL-----EDMKPTGEA 1089 Query: 817 SRITSIFN-FGYVSLNIMHLRAEDAGSYT--VRAVNKLGEAISTASIRVAARSTVTADLG 873 ++ + + L + GS T V + + + ++ V A L Sbjct: 1090 PKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVVDVRRTKMEYTDDV-ATLT 1148 Query: 874 IPEQR---RYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFE 930 IP R + + K P KP+FKT +K + + E A FE Sbjct: 1149 IPTTRPEDKGMYKCVAKNDFGEASTSATLHINP--VVKPDFKTKLKP-MEVTEESVAKFE 1205 Query: 931 ARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAI 990 R G VEW +E S R L I V V DAG Y C N Sbjct: 1206 VR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQA 1263 Query: 991 GQATTSANLTIVTKKDIIAE 1010 G A + A+L V +KD E Sbjct: 1264 GTAYSRADLK-VKEKDCAPE 1282 Score = 62.9 bits (146), Expect = 6e-09 Identities = 42/150 (28%), Positives = 73/150 (48%), Gaps = 5/150 (3%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 FI+ L + KEGD C V PT I WF +N P+ + R ++++ S +L++ Sbjct: 2226 FITGLFPVQIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSALEL 2283 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895 D+G+Y C ATNS+GS ++S + I + GLE+ + + ++ Sbjct: 2284 KEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLESSDMRLDVKI 2343 Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVE 2925 RP+V E+ K +I + H+++E Sbjct: 2344 GGFPRPTV---EFYKDYDLIVDSERHKILE 2370 Score = 62.5 bits (145), Expect = 8e-09 Identities = 43/161 (26%), Positives = 74/161 (45%), Gaps = 6/161 (3%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 +AP +++L P ++SEG+ A EC++ P P +EW+ + + + + +R R D Sbjct: 921 EAPSLVSELQ-PQEISEGEDAKLECKVSGEPQPT--IEWFKDDEPVTTDNRVRADYDGKT 977 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 + L I +D G+Y C A N LG ++ L V K + + Q E + +E+ Sbjct: 978 STLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK-PVEEEKQPEKPKVEKPEVEEP 1036 Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLT 2002 K V++ V KP+ P+ PV +E T Sbjct: 1037 EVEKPEVEEP--VSGKPEVETPVGEVPQEVLAPVTVEVVET 1075 Score = 62.1 bits (144), Expect = 1e-08 Identities = 38/146 (26%), Positives = 72/146 (49%), Gaps = 8/146 (5%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P+F++ L + EG + L+ R++ G T VEW +G+ ++ HR + ++ + L Sbjct: 27 PEFTKKLQPVTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DTSR 1429 ++ +D G Y C ATN++G+A + + V K+ + + + ++ +Q LE D R Sbjct: 85 KIMPSERDDEGEYKCVATNEVGQATITTEVLV---KETLRKPEFKQKMQPLQVLEGDEVR 141 Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIEN 1455 + ID T K + I+N Sbjct: 142 FDVR--IDGKPTPKVEWFKNRTKIDN 165 Score = 62.1 bits (144), Expect = 1e-08 Identities = 130/630 (20%), Positives = 248/630 (39%), Gaps = 105/630 (16%) Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970 PE++ AA + +G+ + + Q+ K P++K WY +GK L G R + + Sbjct: 1281 PEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVK--WYKDGKPLRDGPRTTIRA------ 1332 Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLED 3030 RD +Y CK + + E + +Y N + K T + ++ Sbjct: 1333 --------RDD-LYNCKVLSAKPE---DTGMYKCEATNAVG-----KATRTFD----VQV 1371 Query: 3031 SLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090 + K G +P + P V ++ G+ + +G I+W + K Sbjct: 1372 EVPKPRGSKPSLEAELKP---------VTVTAGEDTKLVCKI--SGKPQPKIDWMKDDKP 1420 Query: 3091 IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPR 3150 ++ R+ Y VL D Y A N+ G +S E + KG P+ Sbjct: 1421 LKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGS--VSTSAELLVNEKGAAPK 1478 Query: 3151 FTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG-FVVL 3209 +Q+++ + G+ A F V P+ +EW+ G+ + V D G F+++ Sbjct: 1479 IEKPLQDVK-VDAGKKATFNTQVSGTPTPE--VEWF-KGESI--------VEDKGRFMII 1526 Query: 3210 DIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269 D D+ E V + + + C V+ + + + AK+ ++++++ A Sbjct: 1527 D-------DAKEGVFQLVIEDAKPEDSGVYKCV----VFNDIGETQTKAKL-QVDAVEVA 1574 Query: 3270 QQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329 + E P + + Q+V V+ + + PD KV WF + + Sbjct: 1575 PKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYV---------PD-KVLWFKDDTPVKTNT 1624 Query: 3330 RYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTK----ANLKCTSKENLIL-DS 3384 + + + L + +++G Y C +T KLG + ++ + I D Sbjct: 1625 TRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDR 1684 Query: 3385 QLPRGMEGG-----LEKLQTLEDSMVRRKDTS-----------VEEEKGKAPVFTVPLSN 3428 L G L+ + + + + K T+ + EK PV PLSN Sbjct: 1685 HLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAVKPVIVKPLSN 1744 Query: 3429 IENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFG---FVILEISPT 3485 ++ + E FE ++ +P +V WY L G+ ++ D G F ++ ++ + Sbjct: 1745 LQ-VEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLI-VNDS 1800 Query: 3486 YPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 DSG Y C A N G+A++ A+++V G+ Sbjct: 1801 QRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830 Score = 62.1 bits (144), Expect = 1e-08 Identities = 40/118 (33%), Positives = 57/118 (48%), Gaps = 8/118 (6%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P+F ++ EV EG+ V L L+ PT EW NG PV+ +R + ++D Y L Sbjct: 1932 PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTL 1989 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 L A ED GTY C A N G A + + + V K Q + I+++E YE Sbjct: 1990 KFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGMIRDIEGYE 2041 Score = 62.1 bits (144), Expect = 1e-08 Identities = 54/195 (27%), Positives = 77/195 (39%), Gaps = 9/195 (4%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 G P T +F V I EG Y +G I WF + + +R+ Y Sbjct: 2222 GVPSFITGLFP--VQIKEGD--KYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASYEGS 2277 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 + LE+ K +D+G Y C ATN G S E K K P F ++ EGL Sbjct: 2278 VSALELKEMKLSDAGLYKCTATNSQGSTSSSA--EVTIKRKDAIPTFVVGLKETEGL--- 2332 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 +S+ V P +E+Y + + S R K + D L I + D+G Y C Sbjct: 2333 ESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKC 2392 Query: 3225 RAYNKYGEDFTRATI 3239 N G + + A I Sbjct: 2393 VITNLLGVETSEAVI 2407 Score = 61.7 bits (143), Expect = 1e-08 Identities = 73/321 (22%), Positives = 125/321 (38%), Gaps = 23/321 (7%) Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGT-KT 3115 V + EG +A + G ++WF + + R V G + I+G K Sbjct: 423 VTVLEGDEIRLDARV--GGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKP 480 Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175 DSG Y C+ATN G+A +++ + P F L + E V Sbjct: 481 LDSGVYICQATNDTGKATAEAEIQIEELLVA--PEFAEEEATQLTLIEDDDMTLELHV-- 536 Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235 P ++ W + +P+ RI ++DI +DSG Y C A NK G + T Sbjct: 537 TGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVN-T 595 Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLV 3295 R I V +E L ++++ + S++ P+ E P+ +Q++ +L Sbjct: 596 RTFI-------VNVEVLFVAGISQV--IGSIRFI--VLAKKPAGEAPEITESLQEMEEL- 643 Query: 3296 EGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEY 3355 EG + P EWF + G RY+ L I +++ EY Sbjct: 644 EGNPVTLTCKFTGTPAP--VAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEY 701 Query: 3356 ECVATNKLGRDSTKANLKCTS 3376 + V N +G ++ ++ T+ Sbjct: 702 QVVIRNDIGSVKSETRVRITA 722 Score = 60.9 bits (141), Expect = 2e-08 Identities = 61/225 (27%), Positives = 89/225 (39%), Gaps = 36/225 (16%) Query: 1978 PQF-GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 P+F G V +G + + A +T P V+WY +G+P++ G R Sbjct: 1281 PEFVGDQAAPIVVRQGEDIDIGAQITA--KPKPNVKWYKDGKPLRDGPRTTIRARDDLYN 1338 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096 +L A EDTG Y C+ATNAVG+A T V+V E+ K Sbjct: 1339 CKVLSAKPEDTGMYKCEATNAVGKATRTFDVQV--------------------EVPKPRG 1378 Query: 2097 PKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156 KP E + +PV +TA G+ C++ P IDW + + ++ Sbjct: 1379 SKPSLEAE--LKPVTVTA---------GEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDK 1425 Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 R T+D L ED Y A N+LG + L V Sbjct: 1426 RVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLV 1470 Score = 60.9 bits (141), Expect = 2e-08 Identities = 77/312 (24%), Positives = 126/312 (40%), Gaps = 41/312 (13%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF--GYV 2035 P+ KP+++ +V G ++ PT VEW+ V+ RF D G Sbjct: 1477 PKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVF 1534 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA-----KSGLYLDTLDEQ-RLKKIQ 2089 L I A ED+G Y C N +GE T + ++VDA K+ LD +E + + Q Sbjct: 1535 QLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQ 1594 Query: 2090 ELE-------KYERPKPI--EEEQPGQ----RPVFLTA---LTSLENLKEGDRAHFECRV 2133 E++ KY K + +++ P + R + +L + D H+ C Sbjct: 1595 EVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCES 1654 Query: 2134 EPINDPHLT-------IDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186 ++ ++W + + I + G L + + +D G Y CK Sbjct: 1655 TTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKV 1714 Query: 2187 TNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHS-TRIEVEEPKISPPRFV 2245 TNKLG A TC + + + P ++ + L+ + S TR EV+ PR V Sbjct: 1715 TNKLGSA--TCGANLIVNEKAV----KPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPR-V 1767 Query: 2246 TELRGTTHVFEG 2257 GTT + EG Sbjct: 1768 AWYHGTTKLIEG 1779 Score = 60.5 bits (140), Expect = 3e-08 Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 4/129 (3%) Query: 1812 SQHESALQKIQQLEDSSRYQRREDVEVAVN-QAPRFITQLNGPTKLSEGQSAHYECRIEP 1870 S ++S + + R DV V V+ +APRF+++L P ++ EG C++ Sbjct: 1899 SLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGKAPRFVSELR-PVEVFEGNEVSLVCKLSA 1957 Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930 P EW NG ++ +R + S D ++ L L ED G Y+C A N G A S Sbjct: 1958 EAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASS 2015 Query: 1931 SIRLNVQSK 1939 +L V+ K Sbjct: 2016 QAKLLVKKK 2024 Score = 60.1 bits (139), Expect = 4e-08 Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 7/118 (5%) Query: 1742 LRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801 ++VEWL++ PI L G L +K+V +D G Y C+ N+LG A + L Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728 Query: 1802 VQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859 V KA + ++ + L+ + R +V++A N PR + +G TKL EG Sbjct: 1729 VNEKAVKPV------IVKPLSNLQVEEKSLTRFEVQIAGNPKPR-VAWYHGTTKLIEG 1779 Score = 60.1 bits (139), Expect = 4e-08 Identities = 71/315 (22%), Positives = 118/315 (37%), Gaps = 16/315 (5%) Query: 67 GEPSPPIF-EQIFKNARFAQGGN-AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 G P P F E K+A + +GG + G PTP V W + L E ++ Sbjct: 1829 GRPCAPTFVEDEVKDAVYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQL--VKIIP 1886 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEA--ICSVYIQPEGXXXXXXXXXXXXXYRHV 182 + L+I + D G Y C A+N +G V ++ +G Sbjct: 1887 KGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGKAPRFVSELRPVEVFEG 1946 Query: 183 SE-TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241 +E ++ K T E SR V N S + F + + + Sbjct: 1947 NEVSLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLA 2006 Query: 242 KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301 K G + Q + + + P+ R+ + EG A+F V +GN P+V W Sbjct: 2007 KNVFGSASSQAKLLVKKK---GNRPQPIGMIRDIEGYEGGQARFDVHFTGN--PKVEWLH 2061 Query: 302 NGQRLINSNKHEIITTHNH--TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP- 358 +++I+ K++I +L V + + D G YT +A N +G L V+ Sbjct: 2062 GEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDKH 2121 Query: 359 -TESYVQDQRSQYIT 372 +V+D + IT Sbjct: 2122 IAPMFVEDDTGEPIT 2136 Score = 60.1 bits (139), Expect = 4e-08 Identities = 46/218 (21%), Positives = 90/218 (41%), Gaps = 11/218 (5%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141 + W+ +G ++ + R+ + L + D+G Y C A NK G A +V ++ V Sbjct: 2157 VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVK-V 2215 Query: 3142 DKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 ++ KG+ P F T + ++ +K+G C V P I W+ + P+ R+ Sbjct: 2216 EELKGRGVPSFITGLFPVQ-IKEGDKYTLVCRV--SGKPKPTITWFRDNTPVHTDNRVVA 2272 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260 + L++ + D+G Y C A N G + A + K + P + + Sbjct: 2273 SYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI------PTFVVGL 2326 Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQ 3298 +E E L+ + + P + +D +V+ + Sbjct: 2327 KETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSE 2364 Score = 59.3 bits (137), Expect = 8e-08 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 G P F L + ++EG+R + RV+ P T++W +G+K++ HR +TT D Sbjct: 24 GTIPEFTKKLQPV-TVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGE 80 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 L I+ + +D G Y C ATN++G+A T + V Sbjct: 81 RCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLV 116 Score = 59.3 bits (137), Expect = 8e-08 Identities = 80/319 (25%), Positives = 127/319 (39%), Gaps = 47/319 (14%) Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982 + EG L L +V K P++K W + K +++ R T+ L L D DSG Sbjct: 230 ITEGDELDLSVRVRGKPKPEIK--WTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSG 287 Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDD 3042 Y CT+K ++H GT E N+E + K Sbjct: 288 RYK-----------------CTAK------SEH--GTASKEFDVNVEKAKPK-------- 314 Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102 G P+FT + + +I E + A E ++ TG+ + EW + ++ + RI+ Sbjct: 315 --GVAPKFTKPLETL-EIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERD 369 Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162 VVLE+ + D Y A N+ G A + + E + +KP F QN+ L Sbjct: 370 KDSVVLEVRHVELDDEALYKVVAKNESGVA--TSEAELLVNEATEKPFFKKTPQNVTVL- 426 Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSG 3220 +G + V P+ ++W+ Q + R V D L I + DSG Sbjct: 427 EGDEIRLDARV--GGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSG 484 Query: 3221 EYVCRAYNKYGEDFTRATI 3239 Y+C+A N G+ A I Sbjct: 485 VYICQATNDTGKATAEAEI 503 Score = 58.8 bits (136), Expect = 1e-07 Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +AP + L+ + + EG+ LE +V P IEWFK+ +TT R+++ +D Sbjct: 921 EAPSLVSELQPQE-ISEGEDAKLECKVSGEPQPT--IEWFKDDEPVTTDNRVRADYDGKT 977 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 TL+I DD G Y C ATN LG +T + + ++ Sbjct: 978 STLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK 1015 Score = 58.8 bits (136), Expect = 1e-07 Identities = 44/156 (28%), Positives = 65/156 (41%), Gaps = 11/156 (7%) Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764 EV +AP F ++ + V E +L P EW RNG P+ NR+ D Sbjct: 1926 EVDGKAPRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFD 1983 Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824 Y L ED GTY+C A N G A + + L V+ K + + I+ + Sbjct: 1984 GRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGMIRDI 2037 Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQ 1860 E Q R DV N P+ + L+G ++ G+ Sbjct: 2038 EGYEGGQARFDVHFTGN--PK-VEWLHGEEQIIHGE 2070 Score = 58.4 bits (135), Expect = 1e-07 Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 7/133 (5%) Query: 903 PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962 P+ PEF ++ ++++EG +AR++ G T VEW+ DG V+ RI T F Sbjct: 21 PDKGTIPEFTKKLQP-VTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTF 77 Query: 963 NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022 + L I D G Y C A N +GQAT + T V K+ + + + ++ +Q Sbjct: 78 DGERCTLKIMPSERDDEGEYKCVATNEVGQATIT---TEVLVKETLRKPEFKQKMQPLQV 134 Query: 1023 LE-DASRYSKRTE 1034 LE D R+ R + Sbjct: 135 LEGDEVRFDVRID 147 Score = 58.4 bits (135), Expect = 1e-07 Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 4/116 (3%) Query: 1295 ARRTKQVR-EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI 1353 A RT V+ E++ P F L ++ EG L CR+ G + WF + P+ Sbjct: 2207 ASRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPV 2264 Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409 T +R +YE AL+L + D+G+Y C ATN G + +S A I +KD I Sbjct: 2265 HTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQG-STSSSAEVTIKRKDAI 2319 Score = 58.0 bits (134), Expect = 2e-07 Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 8/115 (6%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F L+ VT EG +I + R++ G PT +EW+ +G+ ++ R + F +L Sbjct: 27 PEFTKKLQPVTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751 ++ D GEY C A + G A +T ++ T + PE Q +Q L+ Sbjct: 85 KIMPSERDDEGEYKCVATNEVGQAT------ITTEVLVKETLRKPEFKQKMQPLQ 133 Score = 58.0 bits (134), Expect = 2e-07 Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 3/95 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P FT L+ + EG+ + L+A+V+ + P +EW +G + R+K+TFD T Sbjct: 27 PEFTKKLQPVT-VREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCT 83 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 L I DD G Y C ATN +G+A T + +++ Sbjct: 84 LKIMPSERDDEGEYKCVATNEVGQATITTEVLVKE 118 Score = 57.6 bits (133), Expect = 2e-07 Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 3/99 (3%) Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474 +KG P FT L + +REGE +AR+ P VEW +G+ ++ R +T D Sbjct: 22 DKGTIPEFTKKLQPV-TVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFD 78 Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 L+I P+ +D GEY C A N G+A T + V+ Sbjct: 79 GERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVK 117 Score = 57.6 bits (133), Expect = 2e-07 Identities = 56/241 (23%), Positives = 96/241 (39%), Gaps = 18/241 (7%) Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223 E QIEE+ + P F + + + E ++ LE L G P V W + + +T Sbjct: 500 EAEIQIEELLVA-PEFAEEEATQLTLIEDDDMTLE--LHVTGKPKPEVHWTKDNKPLTED 556 Query: 1224 SRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283 R + +DI+ T D+G Y A N G + IV V +++ Q Sbjct: 557 DRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNV----EVLFVAGISQ 612 Query: 1284 AIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMR 1343 I I+ + A + +AP+ + +L +E +EG V L C+ G Sbjct: 613 VIGSIRFIVLAKK---------PAGEAPEITESLQEMEELEGNPVTLTCKF--TGTPAPV 661 Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 EWF P++ G R++ + L + +D+ Y N +G + +R+ Sbjct: 662 AEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRIT 721 Query: 1404 A 1404 A Sbjct: 722 A 722 Score = 57.6 bits (133), Expect = 2e-07 Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 8/117 (6%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F+ L+ V EG ++ ++ PT EW +NG + +R + F Y +L Sbjct: 1932 PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTL 1989 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753 L+ I+D G Y+C A + G A ++A L +++ P+ + I+ +E Y Sbjct: 1990 KFLNAKIEDQGTYSCLAKNVFGSASSQAKL------LVKKKGNRPQPIGMIRDIEGY 2040 Score = 57.6 bits (133), Expect = 2e-07 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 3/91 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 PRFV+ + +E V EG V CKL ++ EW +NG PV + +R + D Y Sbjct: 1932 PRFVSELRPVE-VFEGNEVSLVCKLS--AEAKPTFEWSRNGSPVRLDNRVQASFDGRYST 1988 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 L ++ ED G Y+C A N+ G+ +L Sbjct: 1989 LKFLNAKIEDQGTYSCLAKNVFGSASSQAKL 2019 Score = 57.2 bits (132), Expect = 3e-07 Identities = 102/439 (23%), Positives = 167/439 (38%), Gaps = 42/439 (9%) Query: 3373 KCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENL 3432 +CT K I+ S+ R EG + + T E + +E + P F + ++ L Sbjct: 81 RCTLK---IMPSE--RDDEGEYKCVATNEVGQATITTEVLVKETLRKPEFKQKMQPLQVL 135 Query: 3433 REGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGE 3492 EG+ F+ R+ P KVEW+ N + RF + L I T D+ Sbjct: 136 -EGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADT 192 Query: 3493 YLCRAYNNYGEAVTTASMKVQGKRNI--ILESQLPKGM-EGT-IDKIAALEGYSGTVDTL 3548 Y C A + G++ + V+ K + + P + EG +D + G Sbjct: 193 YKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINITEGDELDLSVRVRGKPKPEIKW 252 Query: 3549 TPEAESGNPPE-FTTTPSD----LILSE---NSSAHFECRLIPVNDSSMRVEWFHNGKPL 3600 T + + + TTT D L+LS+ S ++C + ++ + + K Sbjct: 253 TKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAK 312 Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK--LQVKGRQGIILE 3658 G K LE + +++ C T T K +K Q I +E Sbjct: 313 PKGVAPKFTKP-----LETLEIMEKETARLECTVTGEPAPTTEWLKGDQPLKETQRIKIE 367 Query: 3659 PQLPS------HFKSGTESIQKL----EETLHKREEITIEDEKPNPPRFTVEIKDNIDVP 3708 S H + E++ K+ E + E + +E P F + N+ V Sbjct: 368 RDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFK-KTPQNVTVL 426 Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GFIALDIDYIYARDAG 3766 EG + D RV +PT +DWF + A R ++D +L I D+G Sbjct: 427 EGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSG 484 Query: 3767 EYTCRATNKWGSATTTAKI 3785 Y C+ATN G AT A+I Sbjct: 485 VYICQATNDTGKATAEAEI 503 Score = 57.2 bits (132), Expect = 3e-07 Identities = 76/349 (21%), Positives = 135/349 (38%), Gaps = 22/349 (6%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P+F +++ V E + VRF+ R++ K PK +EW++N + + R+ + + SL Sbjct: 123 PEFKQKMQPLQVLEGDEVRFDVRIDGKPTPK--VEWFKNRTKIDNEGRFEIIDEEDLYSL 180 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI--ILQNQVPRGMKRSEALTQME 3947 I D+ Y C A ++ G+ +S K+ + + P + + L Sbjct: 181 IIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINITEGDELDLSV 240 Query: 3948 ATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTK------FECQLAPVG 4001 K E+ T+D D K+ R T + ++ + K ++C A Sbjct: 241 RVRGKPKPEIKWTKD---DKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKC-TAKSE 296 Query: 4002 DPNMKVEWFFN---GKPLLHKNRFT-PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG-- 4055 E+ N KP +FT P+ + + +GE L G Sbjct: 297 HGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKETARLECTVTGEPAPTTEWLKGDQ 356 Query: 4056 -MDETKAVIKTTGKPGIVYD-SQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVF 4113 + ET+ + K +V + + +++ K+ S T E + ++A P F Sbjct: 357 PLKETQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFF 416 Query: 4114 VSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162 P VTV EG+ R RV G P+P V W + R+ + D Sbjct: 417 KKTPQNVTVLEGDEIRLDARVGGKPEPTVDWFKGDQKVAEEGRFLIVDD 465 Score = 57.2 bits (132), Expect = 3e-07 Identities = 49/199 (24%), Positives = 78/199 (39%), Gaps = 16/199 (8%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G PK V W ++ P+ +R+ H +++ V P DSGTY C A N+ G V + Sbjct: 538 GKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAG--VNT 595 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857 T V + + I Q+ S R+ + +AP L +L Sbjct: 596 RTFIVNVEVLF---------VAGISQVIGSIRFIVL--AKKPAGEAPEITESLQEMEEL- 643 Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 EG C+ P P EW+ ++ G RY+ + L I +D+ EY Sbjct: 644 EGNPVTLTCKFTGTPAP--VAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEY 701 Query: 1918 TCKAINNLGQAVSSIRLNV 1936 N++G S R+ + Sbjct: 702 QVVIRNDIGSVKSETRVRI 720 Score = 57.2 bits (132), Expect = 3e-07 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 3/119 (2%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 +P F K +K EV EG L+ + V PT VEW+C + R++ + Sbjct: 725 RPDFTKKLKPVEVEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYT 782 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 L I +D TY C A+N VG+ +KV K + +R +KI LEK E Sbjct: 783 LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKM-FPPEITRPERTEKIVLLEKEE 840 Score = 57.2 bits (132), Expect = 3e-07 Identities = 36/106 (33%), Positives = 50/106 (47%), Gaps = 4/106 (3%) Query: 2097 PKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155 P +E+ +P G+ P + AL LE L EGD A C++ P T++WF K+ Sbjct: 1077 PITLEDMKPTGEAPKVVDALQPLEAL-EGDEAKLVCKIT--GSPTPTVEWFKEKAKVVDV 1133 Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 R + + L I T ED G Y C A N GEA + TL + Sbjct: 1134 RRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHI 1179 Score = 57.2 bits (132), Expect = 3e-07 Identities = 70/294 (23%), Positives = 117/294 (39%), Gaps = 40/294 (13%) Query: 2196 TCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVF 2255 TC L H+ ++ D + K +L + S + V E K + P+ L+ V Sbjct: 1435 TCVLTF--HKAVLEDEAEYKVVAK-NELGSVSTSAELLVNE-KGAAPKIEKPLQDVK-VD 1489 Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF--GYVSLDIQHCVPEDAG 2313 GK A F QV P +E++ ++ RF I D G L I+ PED+G Sbjct: 1490 AGKKATFNTQVSGTPTPE--VEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSG 1547 Query: 2314 EYSVKAINALGHCTSAISMTVTA------KGSIISESQRPEGLEKIRELESAEPFKRPEI 2367 Y N +G + + V A + E + P + + +E++ + K + Sbjct: 1548 VYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYV 1607 Query: 2368 PEPVT---RQRPVFTQPLQNIDNIQEGQ-------------TAHFDCRLIPVGDPTL--- 2408 P+ V PV T + I + EG+ H+ C T+ Sbjct: 1608 PDKVLWFKDDTPVKTNTTRKIHS--EGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTF 1665 Query: 2409 ----KVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 KVEW +++K I + + G ++ + HV +D+GVY C+ +N LG Sbjct: 1666 LIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLG 1719 Score = 56.8 bits (131), Expect = 4e-07 Identities = 58/243 (23%), Positives = 95/243 (39%), Gaps = 32/243 (13%) Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713 ++E Q V + +V+ + P+ K+ WFK+ + T K + + L++ DD+G Sbjct: 1590 VLEHQEVDMSVKVKGKYVPD-KVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAG 1648 Query: 2714 IYTCKATNLLGEAVST--ASIKIE----------DRHWLLGESLHPDSLDRI-------- 2753 Y C++T LG +ST +K+E DRH L E+ H I Sbjct: 1649 HYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRH--LKEAFHNGVCTLILKHVVQQD 1706 Query: 2754 -GALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFE------CNVEPSRDPTLK 2806 G V + ++ K N+ E V+ + +P + Sbjct: 1707 KGVYKCKVTNKLGSATCGANLIVNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPR 1766 Query: 2807 IEWFFNNKPLPSGTRYKSTHDFS--YVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864 + W+ L GT YK D +L + + DSG+Y C A N G A + +L Sbjct: 1767 VAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLE 1826 Query: 2865 CTG 2867 TG Sbjct: 1827 VTG 1829 Score = 56.8 bits (131), Expect = 4e-07 Identities = 42/130 (32%), Positives = 60/130 (46%), Gaps = 12/130 (9%) Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290 R+EV+ PRFV+ELR VFEG C++ P E+ NG ++ R Sbjct: 1924 RVEVDG---KAPRFVSELR-PVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNR 1977 Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350 +FD Y +L + ED G YS A N G +S + V KG+ RP+ + Sbjct: 1978 VQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPI 2031 Query: 2351 EKIRELESAE 2360 IR++E E Sbjct: 2032 GMIRDIEGYE 2041 Score = 56.4 bits (130), Expect = 5e-07 Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 2/89 (2%) Query: 3824 PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883 P T P+F +++ TV E E + + RV+ K P +EW +G+ + HR +T +D Sbjct: 21 PDKGTIPEFTKKLQPVTVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFD 78 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGE 3912 +L I+ +D GEY C A N+ G+ Sbjct: 79 GERCTLKIMPSERDDEGEYKCVATNEVGQ 107 Score = 56.4 bits (130), Expect = 5e-07 Identities = 37/126 (29%), Positives = 64/126 (50%), Gaps = 6/126 (4%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P FT ++ + V E + +AR+ G P VEW+ +G ++ +R+ T D L Sbjct: 27 PEFTKKLQPVTVREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE-DSSR 1829 + +D G Y C A NE+G+A ++ + V K +L+ + + + +Q +Q LE D R Sbjct: 85 KIMPSERDDEGEYKCVATNEVGQATITTEVLV--KETLR-KPEFKQKMQPLQVLEGDEVR 141 Query: 1830 YQRRED 1835 + R D Sbjct: 142 FDVRID 147 Score = 56.4 bits (130), Expect = 5e-07 Identities = 40/136 (29%), Positives = 59/136 (43%), Gaps = 10/136 (7%) Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159 + E G+ P F++ L +E + EG+ C++ P T +W NG +R +R + Sbjct: 1923 VRVEVDGKAPRFVSELRPVE-VFEGNEVSLVCKLSAEAKP--TFEWSRNGSPVRLDNRVQ 1979 Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEK 2219 + D Y L L ED GTY C A N G A + L V N P + Sbjct: 1980 ASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGM 2033 Query: 2220 IRQLEA-QGHSTRIEV 2234 IR +E +G R +V Sbjct: 2034 IRDIEGYEGGQARFDV 2049 Score = 56.0 bits (129), Expect = 7e-07 Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 6/143 (4%) Query: 907 QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966 + P + ++ Q I EG A E ++ G+ +EW KD PV +R+ ++ Sbjct: 921 EAPSLVSELQPQ-EISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTDNRVRADYDGKT 977 Query: 967 VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDA 1026 LTI+ T+ D G Y C A N +G +TSA ++ + + E + P K++ E Sbjct: 978 STLTIRDATLDDEGDYKCVATNELG--STSATTELLVNEKPVEEEKQP-EKPKVEKPEVE 1034 Query: 1027 SRYSKRTEEEVKITQKPRFLGPL 1049 ++ E E ++ KP P+ Sbjct: 1035 EPEVEKPEVEEPVSGKPEVETPV 1057 Score = 55.6 bits (128), Expect = 9e-07 Identities = 72/309 (23%), Positives = 115/309 (37%), Gaps = 47/309 (15%) Query: 3409 DTSVE--EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466 D +E + KG+AP L E + EGE+A E +++ +P +EW+ + + + Sbjct: 910 DVQIEASKPKGEAPSLVSELQPQE-ISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTD 966 Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV------QGKRNIIL 3520 +R R D L I +D G+Y C A N G T + V + K+ Sbjct: 967 NRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPVEEEKQPEKP 1026 Query: 3521 ESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAE--------------------------S 3554 + + P+ E ++K E SG + TP E + Sbjct: 1027 KVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKPT 1086 Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G P+ L E A C++ + VEWF ++ R K Sbjct: 1087 GEAPKVVDALQPLEALEGDEAKLVCKI--TGSPTPTVEWFKEKAKVVDVRRTKMEYTDDV 1144 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674 L I D G+Y C A N GEA+ S L + P + FK+ + ++ Sbjct: 1145 ATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHI--------NPVVKPDFKTKLKPMEV 1196 Query: 3675 LEETLHKRE 3683 EE++ K E Sbjct: 1197 TEESVAKFE 1205 Score = 55.6 bits (128), Expect = 9e-07 Identities = 91/415 (21%), Positives = 155/415 (37%), Gaps = 79/415 (19%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P F+ L T+ E + +I +P P VE+Y + ++ R++ D + Sbjct: 2320 PTFVVGLK-ETEGLESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSR 1963 L I + ED+G Y C N LG V++ E++IR + E A Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLG---------VETSEAVIRVQEREHA------------ 2415 Query: 1964 YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023 P+F VT L T P V W +G + Sbjct: 2416 --------------PRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSS 2461 Query: 2024 HRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQ 2083 + +L I+ ED+G Y C+A +++G+A + + Sbjct: 2462 NGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDL---------------- 2505 Query: 2084 RLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTI 2143 K E PK ++EE P FL+ L L+ ++EG F+ + + I Sbjct: 2506 ---------KVEAPK-VKEEPPS----FLSELPPLQ-VREG--FEFKLIFKVVTTKDSKI 2548 Query: 2144 DWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203 +W +G+ G + D + L +D+G Y C TNK GE+ ++ + Sbjct: 2549 EWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADI---- 2604 Query: 2204 HRNIILDTQHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRFVTELRGTTHVFEG 2257 +I T+ P + ++ +E+ +G R +VE P+ V G T + G Sbjct: 2605 --SITQKTRKPEAIAPLKSIESVEGGQARFDVEMSAFPLPK-VDWYHGGTKITHG 2656 Score = 55.2 bits (127), Expect = 1e-06 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP FT P++ + + E + A E + G+P EWL+ P++ + R+ D V Sbjct: 317 APKFTKPLETLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVV 374 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 L +++V +D Y A NE G A + + L V Sbjct: 375 LEVRHVELDDEALYKVVAKNESGVATSEAELLV 407 Score = 55.2 bits (127), Expect = 1e-06 Identities = 49/212 (23%), Positives = 86/212 (40%), Gaps = 20/212 (9%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P F + +Q +L+E + E + G P +V W + KPL +R + Sbjct: 512 PEFAEEEATQLTLIEDDDMTLELHVT--GKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCI 569 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA 4092 ++ V P DSG Y C A N G++ ++ +++ + + + + SI I Sbjct: 570 VDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVE----VLFVAGISQVIGSIRFI----- 620 Query: 4093 SWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIV 4152 + ++ P + SL + + EG C+ TG P P W + Sbjct: 621 -------VLAKKPAGEAPEITESLQEMEEL-EGNPVTLTCKFTGTPAPVAEWFKASTPVR 672 Query: 4153 NGSRYKL-TYDGMYHFDIPKTRQYDTGKIEVI 4183 +G RYK+ T D I +TR D + +V+ Sbjct: 673 DGRRYKITTTDNTTTLTIKETRLDDNTEYQVV 704 Score = 55.2 bits (127), Expect = 1e-06 Identities = 58/247 (23%), Positives = 99/247 (40%), Gaps = 31/247 (12%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP+ + L +++ G ++ G T VEWF ++ RF + Sbjct: 1476 APKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533 Query: 1370 LDLL--SVYPEDSGVYTCQATNQLGEAVTSCALRVIA-----KKDLIL-ESQHPSGLEKI 1421 L+ PEDSGVY C N +GE T L+V A K D L E + P + + Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEH 1593 Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENV-IEGQHV-------------HFEC- 1466 Q ++ + + K + D+ + K + + + EG+ H+ C Sbjct: 1594 QEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCE 1653 Query: 1467 ---KLEPVTDSNL---KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCR 1520 KL + L KVEW K+ +P+ + G L + ++ +D G+Y C+ Sbjct: 1654 STTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCK 1713 Query: 1521 AVNLVGT 1527 N +G+ Sbjct: 1714 VTNKLGS 1720 Score = 55.2 bits (127), Expect = 1e-06 Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 5/86 (5%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF--GY 2433 P +PLQ++ + G+ A F+ ++ G PT +VEWF+ E ++ED R D G Sbjct: 1477 PKIEKPLQDV-KVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459 + I + ED GVY C N +GE Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGE 1559 Score = 54.8 bits (126), Expect = 2e-06 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 3/84 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+F ++Q VT + EG+ +AR+ P VEW +G+K+ HR +T D Sbjct: 27 PEFTKKLQPVT-VREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCT 83 Query: 3342 LDILYCYEENSGEYECVATNKLGR 3365 L I+ ++ GEY+CVATN++G+ Sbjct: 84 LKIMPSERDDEGEYKCVATNEVGQ 107 Score = 54.8 bits (126), Expect = 2e-06 Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 7/137 (5%) Query: 1138 RSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHL 1197 ++S++ S I+R + + T H S+ + E+ P FV L P V EG + L Sbjct: 1897 KASLNDSGIYRCVAKNT-HGSVSRTFDVRV---EVDGKAPRFVSEL-RPVEVFEGNEVSL 1951 Query: 1198 ECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNH 1257 C+L PT EW NG V + +R + +D + L ++A D G Y+ A N Sbjct: 1952 VCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNV 2009 Query: 1258 LGSAHTSAIVRVIERSD 1274 GSA + A + V ++ + Sbjct: 2010 FGSASSQAKLLVKKKGN 2026 Score = 54.8 bits (126), Expect = 2e-06 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 3/111 (2%) Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823 E + P+F+ L+ + E+ EG +L+ + PT EW ++G P+ +R+ + F Sbjct: 1926 EVDGKAPRFVSELRPV-EVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASF 1982 Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874 + Y +L ++ + ED G+Y+ A N G A S A + V + +G+ Sbjct: 1983 DGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGNRPQPIGM 2033 Score = 54.4 bits (125), Expect = 2e-06 Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 6/116 (5%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F + L P V EG+ I L+ R++ G PT VEW +G V R KT +D Sbjct: 27 PEFTKKLQ-PVTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCT 83 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLE 1292 L I+ + D GEY A N +G A + V V + + + +Q ++ +Q+LE Sbjct: 84 LKIMPSERDDEGEYKCVATNEVGQATITTEVLV---KETLRKPEFKQKMQPLQVLE 136 Score = 53.6 bits (123), Expect = 4e-06 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764 + + EG CRV G P I WF + P T +RV + AL++ + D Sbjct: 2233 VQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSD 2290 Query: 3765 AGEYTCRATNKWGSATTTAKITCSAK 3790 AG Y C ATN GS +++A++T K Sbjct: 2291 AGLYKCTATNSQGSTSSSAEVTIKRK 2316 Score = 53.2 bits (122), Expect = 5e-06 Identities = 35/107 (32%), Positives = 52/107 (48%), Gaps = 3/107 (2%) Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466 R D V+E K AP F + +R+GE+ A++T PN+K WY +GK L+ G Sbjct: 1269 RADLKVKE-KDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVK--WYKDGKPLRDG 1325 Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 R ++ PED+G Y C A N G+A T ++V+ Sbjct: 1326 PRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372 Score = 53.2 bits (122), Expect = 5e-06 Identities = 87/388 (22%), Positives = 143/388 (36%), Gaps = 30/388 (7%) Query: 1030 SKRTEEEVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086 S T E+ + +K P+ PL+ K+ G+ A F +V T VEW+ + Sbjct: 1461 SVSTSAELLVNEKGAAPKIEKPLQDV-KVDAGKKATFNTQVSGTP--TPEVEWFKGESIV 1517 Query: 1087 TSANRIQTYHDF--GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTS 1144 R D G L I + EDSGVY V N GE Q A + V+ + Sbjct: 1518 EDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKT 1577 Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEG--KNIHLECRLE 1202 + L EK I + E ++ K P V + PV + IH E R+ Sbjct: 1578 D--KKLDEKEEPITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMY 1635 Query: 1203 --PMGDPTMRVEWFHNGRSVT-VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLG 1259 + D ++ + S T +G+ T+ II + + HL Sbjct: 1636 YLTLTDASLDDAGHYRCESTTKLGTTISTFL--------IIVKVEWLKDDKPIAKDRHLK 1687 Query: 1260 SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHN 1319 A + + +I + +V + + L A + + V P + L N Sbjct: 1688 EAFHNGVCTLILK-HVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAV--KPVIVKPLSN 1744 Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL--SVYP 1377 ++ E + E +Q G+ RV W+ + G ++ + L+ Sbjct: 1745 LQVEEKSLTRFE--VQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQR 1802 Query: 1378 EDSGVYTCQATNQLGEAVTSCALRVIAK 1405 DSGVY C A N+ G+A++ L V + Sbjct: 1803 HDSGVYKCVAVNEAGKAISQATLEVTGR 1830 Score = 53.2 bits (122), Expect = 5e-06 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 3/132 (2%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRT-DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERR 1600 I +++ N++G+ + RT D+ EV +AP + L+ VE+ EG + Sbjct: 1895 IYKASLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGKAPRFVSELRPVEVFEGNEVSLVCK 1954 Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 L + T EW N P++ +R + + + L ++ ED GTY+C A N G Sbjct: 1955 LSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGS 2012 Query: 1661 AVTSGIAIVHSK 1672 A + +V K Sbjct: 2013 ASSQAKLLVKKK 2024 Score = 53.2 bits (122), Expect = 5e-06 Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 15/152 (9%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F+S L + EG+ + C + PT EW N P+ R +++ D Y +L Sbjct: 1934 FVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKF 1991 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895 + ED G Y+C A N GSA++ L N PQ + +E E + Sbjct: 1992 LNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGMIRDIEGYEGGQ- 2044 Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQ 2927 R V T PK EW + E Q++ G+ Sbjct: 2045 ---ARFDVHFTGNPKVEW---LHGEEQIIHGE 2070 Score = 52.8 bits (121), Expect = 7e-06 Identities = 81/354 (22%), Positives = 137/354 (38%), Gaps = 58/354 (16%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPA--YEFD 1366 + P F + N+ +EG + L+ R+ + T V+WF + + RF E D Sbjct: 412 EKPFFKKTPQNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGD 469 Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426 +L + + P DSGVY CQATN G+A +++ ++L++ ++ E+ Sbjct: 470 LFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI---EELLVAP---------EFAEE 517 Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486 + + T I D+ +T++ +PK VH+ T N +P Sbjct: 518 EAT-QLTLIEDDDMTLELHVTGKPK--------PEVHW-------TKDN---------KP 552 Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVR-S 1545 +T R H +DI+ + DSG Y C A N G + + T IV Sbjct: 553 LTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVN---------TRTFIVNVE 603 Query: 1546 TQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVS 1605 AG+ Q+ + + +AP T SL+ +E EG + Sbjct: 604 VLFVAGISQV-----IGSIRFIVLAKKPAGEAPEITESLQEMEELEGNPVTLTCKF--TG 656 Query: 1606 DATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 EW+ + P++ G R+ T L I +D+ Y N +G Sbjct: 657 TPAPVAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG 710 Score = 52.8 bits (121), Expect = 7e-06 Identities = 66/277 (23%), Positives = 104/277 (37%), Gaps = 38/277 (13%) Query: 3542 SGTVDT-LTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL 3600 S T+D + G P + +SE A EC++ + +EWF + +P+ Sbjct: 906 STTIDVQIEASKPKGEAPSLVSELQPQEISEGEDAKLECKVS--GEPQPTIEWFKDDEPV 963 Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ-GIILEP 3659 T +RV+ D L I D G Y C ATN G + + +L V + +P Sbjct: 964 TTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPVEEEKQP 1023 Query: 3660 QLPSHFKSGTE--SIQK--LEETLHKREE---------------ITIE----------DE 3690 + P K E ++K +EE + + E +T+E D Sbjct: 1024 EKPKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDM 1083 Query: 3691 KP--NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748 KP P+ V+ ++ EG C++ G PT ++WF R Sbjct: 1084 KPTGEAPK-VVDALQPLEALEGDEAKLVCKI--TGSPTPTVEWFKEKAKVVDVRRTKMEY 1140 Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 L I D G Y C A N +G A+T+A + Sbjct: 1141 TDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATL 1177 Score = 52.8 bits (121), Expect = 7e-06 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 PRF E++ ++V EG V C++ PT +W NG P +RV D + Sbjct: 1932 PRFVSELRP-VEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYST 1988 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 L D G Y+C A N +GSA++ AK+ K Sbjct: 1989 LKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK 2024 Score = 52.4 bits (120), Expect = 9e-06 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 2/82 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F ++ + +EG ++ F+ RI+ G PT K+EW KN I+ RF I SL Sbjct: 123 PEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSL 180 Query: 697 DMLSLNIQDSGEYTCRAVSATG 718 + + D+ Y C A S G Sbjct: 181 IIDDTRLSDADTYKCIATSEAG 202 Score = 52.4 bits (120), Expect = 9e-06 Identities = 55/212 (25%), Positives = 90/212 (42%), Gaps = 37/212 (17%) Query: 1865 ECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFG--FAALDILTVYGEDSGEYTCKAI 1922 + R + + N +VEW + + G +Y+ S + G +L + + ED G YTC A Sbjct: 2044 QARFDVHFTGNPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVAS 2103 Query: 1923 NNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGK 1982 N G A LN ++D +H + + ++EDD+ G+ Sbjct: 2104 NESGDATLHANLN-------VKD-KHIAPM----FVEDDT------------------GE 2133 Query: 1983 PIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYA 2042 PI V G +++ + +P V WY +G +QQ R + + L + A Sbjct: 2134 PIT---VEAGKELNVIMNIR--GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKA 2188 Query: 2043 YAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074 +D G Y C+A N +G A T VKV+ G Sbjct: 2189 VPDDAGIYRCEAKNKLGTASRTVMVKVEELKG 2220 Score = 52.4 bits (120), Expect = 9e-06 Identities = 37/145 (25%), Positives = 69/145 (47%), Gaps = 11/145 (7%) Query: 2218 EKIRQLEAQGHSTRIEVEEPKIS--PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLR 2275 + + L S ++VE PK+ PP F++EL V EG F+ + V + + Sbjct: 2491 QAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELP-PLQVREG--FEFKLIFKVVTTKDSK 2547 Query: 2276 IEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335 IE+ +G+A +FD ++L ++ +DAG Y N G +S+ +++T Sbjct: 2548 IEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISIT 2607 Query: 2336 AKGSIISESQRPEGLEKIRELESAE 2360 K +++PE + ++ +ES E Sbjct: 2608 QK------TRKPEAIAPLKSIESVE 2626 Score = 52.0 bits (119), Expect = 1e-05 Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 12/161 (7%) Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749 +K P FT +++ + V EG + D RV+ G PT ++W +G R+ T D Sbjct: 22 DKGTIPEFTKKLQP-VTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFD 78 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809 L I D GEY C ATN+ G AT T ++ ++ + + + Q M ++ Sbjct: 79 GERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLV---KETLRKPEFKQKMQPLQVL 135 Query: 3810 ELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850 E + R + I P + K+ T ++EG RFE Sbjct: 136 EGDEVRF-----DVRIDGKPTPKVEWFKNRTKIDNEG-RFE 170 Score = 52.0 bits (119), Expect = 1e-05 Identities = 66/244 (27%), Positives = 98/244 (40%), Gaps = 44/244 (18%) Query: 3409 DTSVEEEK--GKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466 D +VE+ K G AP FT PL +E + E E A E T T +P EW + LK Sbjct: 305 DVNVEKAKPKGVAPKFTKPLETLE-IMEKETARLEC--TVTGEPAPTTEWLKGDQPLKET 361 Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPK 3526 R + D V+LE+ +D Y A N G A + A + ++ E+ Sbjct: 362 QRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAEL-------LVNEATEKP 414 Query: 3527 GMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVND 3586 + T + LEG D + +A G PE T D + A E R + V+D Sbjct: 415 FFKKTPQNVTVLEG-----DEIRLDARVGGKPEPTV---DWFKGDQKVAE-EGRFLIVDD 465 Query: 3587 SSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646 + F +I G D+G+Y C+ATN G+AT + Sbjct: 466 EEGDL--------------------FSLII---GNAKPLDSGVYICQATNDTGKATAEAE 502 Query: 3647 LQVK 3650 +Q++ Sbjct: 503 IQIE 506 Score = 52.0 bits (119), Expect = 1e-05 Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 4/118 (3%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 RP FT+ L+ ++ ++EGQ A D R+ VG PT VEWF + D+ R + Sbjct: 725 RPDFTKKLKPVE-VEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSY 781 Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQ 2492 ++ I +D+ Y C ASN +G+ E PE +KI LE+ Sbjct: 782 TLIIKTTVRDDDDTYKCVASNQVGK-VTCRGDLKVTEKMFPPEITRPERTEKIVLLEK 838 Score = 52.0 bits (119), Expect = 1e-05 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P+F+++++ V E V C++ + P EW RNG + +R + +D + +L Sbjct: 1932 PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTL 1989 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 L ED G Y C A N FG ++A + KK Sbjct: 1990 KFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKK 2023 Score = 51.6 bits (118), Expect = 2e-05 Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 8/156 (5%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E+ +KPEFK ++ + + EG F+ R++ G T +VEW K+ ++ R Sbjct: 116 VKETLRKPEFKQKMQP-LQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEII 172 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI--IAESQHPGGLEK 1019 +L I + DA Y C A + G++T L++ K + P + + Sbjct: 173 DEEDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINITE 232 Query: 1020 IQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKI 1055 L+ + R + + E+K T+ + P+K T+++ Sbjct: 233 GDELDLSVRVRGKPKPEIKWTKDDK---PIKKTDRL 265 Score = 51.6 bits (118), Expect = 2e-05 Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 3/83 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P FT+PL+ ++ I E +TA +C + G+P EW + ++ ++++ RI D V Sbjct: 318 PKFTKPLETLE-IMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVV 374 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 + + HV +DE +Y A N G Sbjct: 375 LEVRHVELDDEALYKVVAKNESG 397 Score = 51.6 bits (118), Expect = 2e-05 Identities = 43/147 (29%), Positives = 68/147 (46%), Gaps = 6/147 (4%) Query: 3395 EKLQTLEDSMVRRKDTSVEEEK--GKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNL 3452 E L + +V ++E+ K G+AP L +E L EG+ A ++T + P Sbjct: 1063 EVLAPVTVEVVETAPITLEDMKPTGEAPKVVDALQPLEAL-EGDEAKLVCKITGSPTPT- 1120 Query: 3453 KVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 VEW+ + R + L I T PED G Y C A N++GEA T+A++ + Sbjct: 1121 -VEWFKEKAKVVDVRRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHI 1179 Query: 3513 QGKRNIILESQLPKGMEGTIDKIAALE 3539 +++L K ME T + +A E Sbjct: 1180 NPVVKPDFKTKL-KPMEVTEESVAKFE 1205 Score = 51.6 bits (118), Expect = 2e-05 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 4/112 (3%) Query: 1030 SKRTEEEVKITQK-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088 S+ + V++ K PRF+ L+ ++ EG ++ ++ T EW NG + Sbjct: 1918 SRTFDVRVEVDGKAPRFVSELRPV-EVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRL 1974 Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140 NR+Q D Y L + + ED G Y+ +A+N G A A + V+ + + Sbjct: 1975 DNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN 2026 Score = 51.6 bits (118), Expect = 2e-05 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 3/102 (2%) Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159 +EE + P F+T L ++ +KEGD+ CRV P TI WF + + +R Sbjct: 2215 VEELKGRGVPSFITGLFPVQ-IKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVV 2271 Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 +++ AL++ D+G Y C ATN G ++ + + Sbjct: 2272 ASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTI 2313 Score = 51.6 bits (118), Expect = 2e-05 Identities = 38/102 (37%), Positives = 50/102 (49%), Gaps = 7/102 (6%) Query: 2104 QPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR---- 2159 Q ++P + L S+E++ EG +A F+ VE P +DW+H G KI G RY+ Sbjct: 2608 QKTRKPEAIAPLKSIESV-EGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQS 2664 Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 T D L I DSGTY C ATN+ G LKV Sbjct: 2665 TDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706 Score = 51.2 bits (117), Expect = 2e-05 Identities = 53/193 (27%), Positives = 76/193 (39%), Gaps = 16/193 (8%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 V W + K +T +RI H +DI +V DSG Y A+N AG + + VE Sbjct: 544 VHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVE 603 Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196 S + + R I +K +P + EI++S +Q + EG + Sbjct: 604 VLFVAGISQVIGSI----RFIVLAK--KPAGEAPEITES----LQEMEE----LEGNPVT 649 Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256 L C+ G P EWF V G R+K L I D EY V N Sbjct: 650 LTCKFT--GTPAPVAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRN 707 Query: 1257 HLGSAHTSAIVRV 1269 +GS + VR+ Sbjct: 708 DIGSVKSETRVRI 720 Score = 51.2 bits (117), Expect = 2e-05 Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 3/106 (2%) Query: 1833 REDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH 1891 R D++V AP F+ P + +G+ +I P PN V+WY +GK L+ G Sbjct: 1269 RADLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPN--VKWYKDGKPLRDGP 1326 Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 R +L+ ED+G Y C+A N +G+A + + V+ Sbjct: 1327 RTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372 Score = 51.2 bits (117), Expect = 2e-05 Identities = 83/381 (21%), Positives = 147/381 (38%), Gaps = 29/381 (7%) Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612 E G P+ D+ + A F ++ + VEWF + R I+D Sbjct: 1472 EKGAAPKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDA 1529 Query: 3613 --GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTE 3670 G L I D+G+Y C N GE KLQV + + P+ E Sbjct: 1530 KEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQV---DAVEVAPKTDKKLDEKEE 1586 Query: 3671 SIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEG--GPVHFDCRVEPVGDPTMR 3728 I LE H+ +++++ + P + KD+ V +H + R+ + Sbjct: 1587 PITVLE---HQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDAS 1643 Query: 3729 IDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788 +D + R +T T++ F I + ++++ +D + A T Sbjct: 1644 LDDAGHYRCESTTKLGTTISTF-LIIVKVEWL--KD--DKPIAKDRHLKEAFHNGVCTLI 1698 Query: 3789 AKRDIVLESQLPQGMSGEKIKELERGR--ISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846 K + + + + K+ G I + +P++ P + + VEE Sbjct: 1699 LKHVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAVKPVIVKP------LSNLQVEEKSL 1752 Query: 3847 VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE--DSGEYIC 3904 RFE V+ +PK R+ WY L G Y+ + D G + ++ ++ DSG Y C Sbjct: 1753 TRFE--VQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKC 1810 Query: 3905 RAVNDFGEDFTKATISCKKLP 3925 AVN+ G+ ++AT+ P Sbjct: 1811 VAVNEAGKAISQATLEVTGRP 1831 Score = 51.2 bits (117), Expect = 2e-05 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 3/98 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +AP F + L+ + + EG V L ++ P EW +NG + R++++FD Sbjct: 1930 KAPRFVSELRPVE-VFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRY 1986 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 TL + + +D G Y+C A N+ G A S A + ++ + Sbjct: 1987 STLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK 2024 Score = 51.2 bits (117), Expect = 2e-05 Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 3/90 (3%) Query: 919 ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978 + IKEG R+ G + W +D PV +R+ + AL +K + + D Sbjct: 2233 VQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSD 2290 Query: 979 AGHYTCRAYNAIGQATTSANLTIVTKKDII 1008 AG Y C A N+ G ++SA +TI +KD I Sbjct: 2291 AGLYKCTATNSQGSTSSSAEVTI-KRKDAI 2319 Score = 50.8 bits (116), Expect = 3e-05 Identities = 36/128 (28%), Positives = 49/128 (38%), Gaps = 2/128 (1%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F L + E + EC V PT EW ++PL R K D V L++ Sbjct: 320 FTKPLETLEIMEKETARLECTVTGEPAPTT--EWLKGDQPLKETQRIKIERDKDSVVLEV 377 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895 H +D +Y A N G AT+ L F + PQ LE E +AR+ Sbjct: 378 RHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLEGDEIRLDARV 437 Query: 2896 AKGRRPSV 2903 P+V Sbjct: 438 GGKPEPTV 445 Score = 50.8 bits (116), Expect = 3e-05 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 1/97 (1%) Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022 DL +K PP +T+ + +V +E + + +G+P V+WF +GKP+ +R Sbjct: 812 DLKVTEKMFPPE-ITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRL 870 Query: 4023 TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDET 4059 +N PED+G Y C A N G T Sbjct: 871 NIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSST 907 Score = 50.4 bits (115), Expect = 3e-05 Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 3/88 (3%) Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431 T ++P F Q +Q + + EG FD R+ G PT KVEWF+N I++ R + Sbjct: 119 TLRKPEFKQKMQPLQ-VLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEE 175 Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLGE 2459 S+ I R D Y C A++ G+ Sbjct: 176 DLYSLIIDDTRLSDADTYKCIATSEAGK 203 Score = 50.4 bits (115), Expect = 3e-05 Identities = 46/200 (23%), Positives = 81/200 (40%), Gaps = 36/200 (18%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595 G+P WY +G L+ R + + L + V +DAG+Y C+A N+ G Sbjct: 2151 GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRT 2210 Query: 2596 XXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLV 2655 ++++E VP TG +F +K DK Sbjct: 2211 V---------------------MVKVEELKGRGVPSFI--TG-----LFPVQIKEGDKYT 2242 Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 L +V + P I WF++ + T R+ ++++ + L + ++ D+G+Y Sbjct: 2243 ------LVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLY 2294 Query: 2716 TCKATNLLGEAVSTASIKIE 2735 C ATN G S+A + I+ Sbjct: 2295 KCTATNSQGSTSSSAEVTIK 2314 Score = 50.0 bits (114), Expect = 5e-05 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 3/93 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+F + LQ + ++EG +A++ PT VEW DG + RI + F+ + Sbjct: 27 PEFTKKLQPV-TVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCT 83 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 L IM +D G Y A N++G+A T + V Sbjct: 84 LKIMPSERDDEGEYKCVATNEVGQATITTEVLV 116 Score = 50.0 bits (114), Expect = 5e-05 Identities = 46/219 (21%), Positives = 84/219 (38%), Gaps = 18/219 (8%) Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705 +T +E + E + G P ++ W K+ + + R + +D++++ D Sbjct: 522 LTLIEDDDMTLELHV--TGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPND 579 Query: 706 SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQ 765 SG Y C A + GV +++V + SQ ++++I ++ Sbjct: 580 SGTYKCEAKNKAGVNTRTFIVNVEV-LFVAGISQVIGSIRFI------------VLAKKP 626 Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825 + P+ LQ++ EL EG + T P EW+K P+ R Sbjct: 627 AGEAPEITESLQEMEEL-EGNPVTLTCKFTGTPAPV--AEWFKASTPVRDGRRYKITTTD 683 Query: 826 GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864 +L I R +D Y V N +G S +R+ A Sbjct: 684 NTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITA 722 Score = 50.0 bits (114), Expect = 5e-05 Identities = 23/63 (36%), Positives = 37/63 (58%) Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 V+W+ +GKP++ G R D +LS PED+G+Y C+ATN +G+A + ++V Sbjct: 1313 VKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372 Query: 1404 AKK 1406 K Sbjct: 1373 VPK 1375 Score = 50.0 bits (114), Expect = 5e-05 Identities = 59/289 (20%), Positives = 120/289 (41%), Gaps = 34/289 (11%) Query: 1815 ESALQKIQQLEDSSRYQRREDVEV-AVNQAPRFITQLNG---PTKLSEGQSAHYECRIEP 1870 +S + K D Q + ++V AV AP+ +L+ P + E Q +++ Sbjct: 1545 DSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKG 1604 Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930 P+ +V W+ + +++ + ++ L + +D+G Y C++ LG +S Sbjct: 1605 KYVPD-KVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTIS 1663 Query: 1931 SIRLNVQ----------SKESIIRDSQHESA---LEKIQYLEDDSRYKRAVQDD------ 1971 + + V+ +K+ ++++ H + K +D YK V + Sbjct: 1664 TFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATC 1723 Query: 1972 --SFVVE----KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR 2025 + +V KP KP+ N +V E E + +P RV WY + +G Sbjct: 1724 GANLIVNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTI 1781 Query: 2026 FKTTYDFGYVALDILY--AYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 +K D G ++ + D+G Y C A N G+A++ ++++V + Sbjct: 1782 YKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830 Score = 50.0 bits (114), Expect = 5e-05 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P FIT L P ++ EG CR+ P P + W+ + + + +R S + +A Sbjct: 2224 PSFITGLF-PVQIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSA 2280 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942 L++ + D+G Y C A N+ G SS + ++ K++I Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319 Score = 50.0 bits (114), Expect = 5e-05 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 10/152 (6%) Query: 907 QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966 + P F + + + ++EG F+ + + ++EW KDGR F+ Sbjct: 2515 EPPSFLSELPP-LQVREG--FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRN 2571 Query: 967 VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDA 1026 + L K+ T+ DAG Y C N G++++SA+++I K ++ P + ++ +E Sbjct: 2572 ITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK------TRKPEAIAPLKSIESV 2625 Query: 1027 SRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058 R + E+ P+ + G KI G Sbjct: 2626 EGGQARFDVEMSAFPLPK-VDWYHGGTKITHG 2656 Score = 49.6 bits (113), Expect = 6e-05 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 2/98 (2%) Query: 4715 PDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773 PD+ +P T L+ + V EG+ ++ K PT++W+ +G + + + +G Sbjct: 21 PDKG-TIPEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKVQDDHRIKTTFDG 79 Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 L I + +D G + C AT GQ + +++VK Sbjct: 80 ERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVK 117 Score = 49.6 bits (113), Expect = 6e-05 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F L + +EG+ I + V+ PT +EW + + + R K+T D +L I Sbjct: 29 FTKKLQPVTVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCTLKI 86 Query: 2836 THTYEEDSGIYTCKATNSKGSAT 2858 + +D G Y C ATN G AT Sbjct: 87 MPSERDDEGEYKCVATNEVGQAT 109 Score = 49.6 bits (113), Expect = 6e-05 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 3/96 (3%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P F +++ + V EG V FD R++ G PT +++WF N R +++ + Sbjct: 123 PEFKQKMQP-LQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYS 179 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 L ID DA Y C AT++ G +T +++ K Sbjct: 180 LIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEK 215 Score = 49.6 bits (113), Expect = 6e-05 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P+F KP++ E+ E LE T+T +P EW +P+++ R K D V L Sbjct: 318 PKFTKPLETLEIMEKETARLECTVT--GEPAPTTEWLKGDQPLKETQRIKIERDKDSVVL 375 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 ++ + +D Y A N G A + + + V+ Sbjct: 376 EVRHVELDDEALYKVVAKNESGVATSEAELLVN 408 Score = 49.6 bits (113), Expect = 6e-05 Identities = 58/260 (22%), Positives = 101/260 (38%), Gaps = 22/260 (8%) Query: 1289 QLLEDAARRTKQVREDIT-VMQAPQFSRA-LHNIETVEGTNVHLECRLQPVGDQTMRVEW 1346 Q D + T + I ++ AP+F+ + +E ++ LE L G V W Sbjct: 489 QATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLE--LHVTGKPKPEVHW 546 Query: 1347 FCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406 + KP+ R ++ D +D+++V P DSG Y C+A N+ G + + V Sbjct: 547 TKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNV---- 602 Query: 1407 DLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFEC 1466 E +G+ ++ + + + P + +E +EG V C Sbjct: 603 ----EVLFVAGISQV-----IGSIRFIVLAKKPAGEAPEITESLQEMEE-LEGNPVTLTC 652 Query: 1467 KLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 K T + + EWFK PV G R++ L I + +D+ Y N +G Sbjct: 653 KFTG-TPAPV-AEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG 710 Query: 1527 T--DEVSCRLTCRSTTDIVR 1544 + E R+T D + Sbjct: 711 SVKSETRVRITALVRPDFTK 730 Score = 49.6 bits (113), Expect = 6e-05 Identities = 55/227 (24%), Positives = 91/227 (40%), Gaps = 38/227 (16%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 ++V+E K P FV + V +G+ Q+ PN +++Y +GK L+ R Sbjct: 1272 LKVKE-KDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPN--VKWYKDGKPLRDGPRT 1328 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 I + + PED G Y +A NA+G T + V E +P G Sbjct: 1329 TIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQV--------EVPKPRG-- 1378 Query: 2352 KIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVE 2411 ++P E+ +PVT + G+ C++ G P K++ Sbjct: 1379 -------SKPSLEAEL-KPVT---------------VTAGEDTKLVCKI--SGKPQPKID 1413 Query: 2412 WFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 W +++K ++ R+ T+D +T EDE Y A N LG Sbjct: 1414 WMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELG 1460 Score = 49.6 bits (113), Expect = 6e-05 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+F+ +++G + AQ+T + P V+WYKDG+P+ R T + Sbjct: 1281 PEFVGDQAAPIVVRQGEDIDIGAQIT--AKPKPNVKWYKDGKPLRDGPRTTIRARDDLYN 1338 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 ++ + ED G Y A N +G+A T ++V Sbjct: 1339 CKVLSAKPEDTGMYKCEATNAVGKATRTFDVQV 1371 Score = 49.6 bits (113), Expect = 6e-05 Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 6/119 (5%) Query: 3951 KKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWF 4010 K V T D +VD K P RFV++++ + E C+L+ P EW Sbjct: 1911 KNTHGSVSRTFDVRVEVDGKAP-RFVSELRP-VEVFEGNEVSLVCKLSAEAKPTF--EWS 1966 Query: 4011 FNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG--MDETKAVIKTTG 4067 NG P+ NR +D Y + F ED G Y C A N++G + K ++K G Sbjct: 1967 RNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKG 2025 Score = 49.6 bits (113), Expect = 6e-05 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 38/203 (18%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G PK + W R+ P+ NR+ ++ AL +K + D+G Y C A N G +S Sbjct: 2249 GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSS 2308 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857 + + ++ K ++ L++ + LE S ++V + PR PT Sbjct: 2309 AEVTIKRKDAI---PTFVVGLKETEGLESSDM-----RLDVKIGGFPR-------PT--- 2350 Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 +E Y D ++ V+ K+L+ G R +L I + ED+G Y Sbjct: 2351 ----------VEFYKDYDLIVD-SERHKILEDGDR---------CSLIITNLRPEDAGTY 2390 Query: 1918 TCKAINNLGQAVSSIRLNVQSKE 1940 C N LG S + VQ +E Sbjct: 2391 KCVITNLLGVETSEAVIRVQERE 2413 Score = 49.6 bits (113), Expect = 6e-05 Identities = 32/96 (33%), Positives = 46/96 (47%), Gaps = 6/96 (6%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG---- 692 P+ I PLKS+ ++EGG+ F+ +E P K++W G I R+ I Sbjct: 2613 PEAIAPLKSIESVEGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGDRP 2670 Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 +L + SL DSG Y C A + GV K+ L V Sbjct: 2671 VYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706 Score = 49.2 bits (112), Expect = 8e-05 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 2/93 (2%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP+F++ L +E +E LEC + G+ EW +P+K R + + D V Sbjct: 317 APKFTKPLETLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVV 374 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L++ V +D +Y A N+ G A + L V Sbjct: 375 LEVRHVELDDEALYKVVAKNESGVATSEAELLV 407 Score = 49.2 bits (112), Expect = 8e-05 Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 4/85 (4%) Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDD 2711 ++EG + L+A+V + +P ++WFK + R D L +L I + + D Sbjct: 425 VLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLD 482 Query: 2712 SGIYTCKATNLLGEAVSTASIKIED 2736 SG+Y C+ATN G+A + A I+IE+ Sbjct: 483 SGVYICQATNDTGKATAEAEIQIEE 507 Score = 49.2 bits (112), Expect = 8e-05 Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 8/129 (6%) Query: 2216 GLEKIRQLEAQGHSTR-----IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVH 2270 G+ K A G +TR +EV +P+ S P EL+ T V G+ C++ Sbjct: 1350 GMYKCEATNAVGKATRTFDVQVEVPKPRGSKPSLEAELKPVT-VTAGEDTKLVCKISGKP 1408 Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330 P +I++ + K L+ R T+D L V ED EY V A N LG +++ Sbjct: 1409 QP--KIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSA 1466 Query: 2331 SMTVTAKGS 2339 + V KG+ Sbjct: 1467 ELLVNEKGA 1475 Score = 49.2 bits (112), Expect = 8e-05 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 5/112 (4%) Query: 1166 MYQIEEIS-KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224 M ++EE+ + P F+ L P + EG L CR+ G P + WF + V + Sbjct: 2212 MVKVEELKGRGVPSFITGLF-PVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDN 2268 Query: 1225 RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276 R Y+ AL++ +D G Y A N GS +SA V I+R D + Sbjct: 2269 RVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEV-TIKRKDAI 2319 Score = 49.2 bits (112), Expect = 8e-05 Identities = 34/144 (23%), Positives = 66/144 (45%), Gaps = 6/144 (4%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P FIT + ++E + CRV K PK I W+R+ + + +R Y+ +L Sbjct: 2224 PSFITGLFPVQIKEGDKYTLVCRVSGK--PKPTITWFRDNTPVHTDNRVVASYEGSVSAL 2281 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPRGMKRSEALTQM 3946 ++ + D+G Y C A N G + A ++ K+ +P ++ + G++ S+ + Sbjct: 2282 ELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLESSDMRLDV 2341 Query: 3947 E-ATIKKYTSEVYLTEDDLYDVDK 3969 + + T E Y D + D ++ Sbjct: 2342 KIGGFPRPTVEFYKDYDLIVDSER 2365 Score = 49.2 bits (112), Expect = 8e-05 Identities = 25/68 (36%), Positives = 36/68 (52%) Query: 2670 TDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729 T + KIEW K+G T G + +FD +TL+ + D+G Y C TN GE+ S+ Sbjct: 2542 TTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSS 2601 Query: 2730 ASIKIEDR 2737 A I I + Sbjct: 2602 ADISITQK 2609 Score = 48.8 bits (111), Expect = 1e-04 Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 3/132 (2%) Query: 1535 TCRSTTDIVRSTQNEAGLE-QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQ 1593 T +TT ++ T+ + E Q+ + D V P T LK VE++EGQ Sbjct: 682 TDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEVEEGQ 741 Query: 1594 RAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCR 1653 A + R+ V T VEW+ L R+ L I + + +D TY C Sbjct: 742 EARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCV 799 Query: 1654 AINALGEAVTSG 1665 A N +G+ G Sbjct: 800 ASNQVGKVTCRG 811 Score = 48.8 bits (111), Expect = 1e-04 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 2/98 (2%) Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034 V KP F +K EVTE E T P VEW+ ++ RF+ + Sbjct: 1182 VVKPDFKTKLKPMEVTEESVAKFEVRSTGFPQP--EVEWFLGSTKIEDSGRFRVVSEQDR 1239 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 L I +D GTY C N G A + + +KV K Sbjct: 1240 HELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK 1277 Score = 48.8 bits (111), Expect = 1e-04 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969 KP + P++ Q+ E + E Q+ +P ++ WY L +G+ +K+ D G Sbjct: 1735 KPVIVKPLS-NLQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791 Query: 2970 TLDLV--DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006 T L+ D DSG+Y C A N+ G+A + +T+ T + Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830 Score = 48.8 bits (111), Expect = 1e-04 Identities = 36/115 (31%), Positives = 52/115 (45%), Gaps = 4/115 (3%) Query: 3403 SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKS 3462 S+ R D VE + GKAP F L +E + EG +L+ P EW NG Sbjct: 1916 SVSRTFDVRVEVD-GKAPRFVSELRPVE-VFEGNEVSLVCKLSAEAKPTF--EWSRNGSP 1971 Query: 3463 LKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517 ++ +R + D + L+ ED G Y C A N +G A + A + V+ K N Sbjct: 1972 VRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN 2026 Score = 48.4 bits (110), Expect = 1e-04 Identities = 21/51 (41%), Positives = 29/51 (56%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 V+WY + KPL+ G R T ++S PED+G Y C A NA+G+A Sbjct: 1313 VKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKA 1363 Score = 48.4 bits (110), Expect = 1e-04 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612 + GN P+ D+ E A F+ + +VEW H + ++ G + K + Sbjct: 2023 KKGNRPQPIGMIRDIEGYEGGQARFDVHFT----GNPKVEWLHGEEQIIHGEKYKISENP 2078 Query: 3613 GFVI--LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 G + L +G + D G YTC A+N G+AT+ L VK + Sbjct: 2079 GEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120 Score = 48.4 bits (110), Expect = 1e-04 Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 6/138 (4%) Query: 1023 LEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFN 1082 L ASR EE+K P F+ L +I EG RV + T+T W+ + Sbjct: 2204 LGTASRTVMVKVEELKGRGVPSFITGLFPV-QIKEGDKYTLVCRVSGKPKPTIT--WFRD 2260 Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142 + + NR+ ++ AL++ ++ D+G+Y A N+ G SA +T++ + +I Sbjct: 2261 NTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIP 2320 Query: 1143 TSSIHRGLYEKTRHIEES 1160 T + GL E T +E S Sbjct: 2321 TFVV--GLKE-TEGLESS 2335 Score = 48.0 bits (109), Expect = 2e-04 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%) Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367 ++ P+F + + ++ +EG V + R+ G T +VEWF N I RF E D Sbjct: 120 LRKPEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDL 177 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 +L + D+ Y C AT++ G++ L V K Sbjct: 178 YSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEK 215 Score = 48.0 bits (109), Expect = 2e-04 Identities = 51/200 (25%), Positives = 72/200 (36%), Gaps = 18/200 (9%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595 G P W + L R H +DI +V ND+G Y C+A N+AG Sbjct: 538 GKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRT 597 Query: 2596 XXXXXXXXXXI-IDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKL 2654 I Q + ++ + K P +AP T L+ ++L Sbjct: 598 FIVNVEVLFVAGISQVIG-------SIRFIVLAKKP-------AGEAPEITESLQEMEEL 643 Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714 EG V L + P EWFK + G R K T TL+I R DD+ Sbjct: 644 -EGNPVTLTCKFTGTPAP--VAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTE 700 Query: 2715 YTCKATNLLGEAVSTASIKI 2734 Y N +G S ++I Sbjct: 701 YQVVIRNDIGSVKSETRVRI 720 Score = 48.0 bits (109), Expect = 2e-04 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 1/102 (0%) Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474 EK P T P E + E +T +P V+W+ +GK ++ SR Sbjct: 817 EKMFPPEITRP-ERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPR 875 Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516 L I T PED+G Y C A N G + TT ++++ + Sbjct: 876 GDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIEASK 917 Score = 48.0 bits (109), Expect = 2e-04 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 2/114 (1%) Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601 S TV E + P F T + + E CR+ + WF + P+ Sbjct: 2208 SRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVH 2265 Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI 3655 T +RV + LE+ + DAGLY C ATN G + S ++ +K + I Sbjct: 2266 TDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319 Score = 48.0 bits (109), Expect = 2e-04 Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 2/85 (2%) Query: 644 KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI 703 +SVTA EG +++ I G P + W+K+G I +S+ + R SL ++ + Sbjct: 2425 QSVTAQEGFELNKTFIIR--GKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTK 2482 Query: 704 QDSGEYTCRAVSATGVAETKAVLHV 728 +DSG YTC+AVS+ G A L V Sbjct: 2483 EDSGNYTCQAVSSLGKASQSFDLKV 2507 Score = 47.6 bits (108), Expect = 2e-04 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 11/142 (7%) Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612 + G PEFT + + E + R+ + VEW +G+ + R+KT D Sbjct: 22 DKGTIPEFTKKLQPVTVREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHRIKTTFDG 79 Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672 L+I + D G Y C ATN G+AT++ ++ VK E FK + + Sbjct: 80 ERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVK-------ETLRKPEFKQKMQPL 132 Query: 3673 QKLEETLHKREEITIEDEKPNP 3694 Q LE R ++ I D KP P Sbjct: 133 QVLEGD-EVRFDVRI-DGKPTP 152 Score = 47.6 bits (108), Expect = 2e-04 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P F L+ + EG+ +ARV+ + T TVEW +G+++ +RI+T D Sbjct: 27 PEFTKKLQPVT-VREGERISLDARVKGKP--TPTVEWMVDGEKVQDDHRIKTTFDGERCT 83 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 L I +D G Y VA N G+A ++ + V+ Sbjct: 84 LKIMPSERDDEGEYKCVATNEVGQATITTEVLVK 117 Score = 47.6 bits (108), Expect = 2e-04 Identities = 41/158 (25%), Positives = 62/158 (39%), Gaps = 6/158 (3%) Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767 T AP I + E R+ G PK ++W ++ PI+ ++RLTT Sbjct: 216 TSAPEVFGDTAPINITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDE 273 Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827 L + PEDSG Y C A +E G A + V+ + + L+ ++ +E Sbjct: 274 CVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKE 333 Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYE 1865 + R + V AP L G L E Q E Sbjct: 334 T---ARLECTVTGEPAPT-TEWLKGDQPLKETQRIKIE 367 Score = 47.6 bits (108), Expect = 2e-04 Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 4/119 (3%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167 RP F L +E ++EG A + RV + P ++WF K+ RY + Sbjct: 725 RPDFTKKLKPVE-VEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSY 781 Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226 L I T +D TY C A+N++G+ LKV + + P EKI LE + Sbjct: 782 TLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVT-EKMFPPEITRPERTEKIVLLEKE 839 Score = 47.6 bits (108), Expect = 2e-04 Identities = 21/65 (32%), Positives = 38/65 (58%) Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 +P ++WFK+G + +RL TL+I++ +D+G YTC+A N +G + +T Sbjct: 850 NPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTI 909 Query: 2731 SIKIE 2735 ++IE Sbjct: 910 DVQIE 914 Score = 47.6 bits (108), Expect = 2e-04 Identities = 57/242 (23%), Positives = 85/242 (35%), Gaps = 38/242 (15%) Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737 T + R ++ ++ EK P F + I V +G + ++ P + W+ +G+P Sbjct: 1265 TAYSRADLKVK-EKDCAPEFVGDQAAPIVVRQGEDIDIGAQI--TAKPKPNVKWYKDGKP 1321 Query: 3738 FATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLES 3797 G R + D G Y C ATN G AT T D+ +E Sbjct: 1322 LRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTF--------DVQVEV 1373 Query: 3798 QLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKE 3857 P+G EL +P+ TV E + C++ K Sbjct: 1374 PKPRGSKPSLEAEL-----------KPV--------------TVTAGEDTKLVCKISGKP 1408 Query: 3858 DPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKA 3917 PK I+W ++ K L R YD L ED EY A N+ G T A Sbjct: 1409 QPK--IDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSA 1466 Query: 3918 TI 3919 + Sbjct: 1467 EL 1468 Score = 47.6 bits (108), Expect = 2e-04 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 3/96 (3%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P F + ++ + + EG +L T EW ++G PV +R+ F+ Y Sbjct: 1932 PRFVSELRP-VEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYST 1988 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 L + + D G Y+C A N G A++ A L + K Sbjct: 1989 LKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK 2024 Score = 47.6 bits (108), Expect = 2e-04 Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 7/100 (7%) Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLV--PVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337 EPP F++++ + ++ EG FE +L+ V D K+EW +G+ G D Sbjct: 2515 EPPSFLSELPPL-QVREG----FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDG 2569 Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377 + L +++G Y+C+ TNK G S+ A++ T K Sbjct: 2570 RNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609 Score = 47.6 bits (108), Expect = 2e-04 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 7/101 (6%) Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ----TY 1095 T+KP + PLK VEG A F+ VE + V+WY G +IT R + T Sbjct: 2610 TRKPEAIAPLKSIES-VEGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTD 2666 Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 D L I S++ DSG Y +A N G + + + V+ Sbjct: 2667 GDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVK 2707 Score = 47.2 bits (107), Expect = 3e-04 Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 4/117 (3%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566 +P FT+ L P E+ EGQ A + RVV G P+ EW+ +L R+ + Sbjct: 725 RPDFTKKLK-PVEVEEGQEARLDVRVV--GTPTPNVEWFCGTTKLTDTDRYEFIEEGDSY 781 Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKE 2623 TL I + V +D Y C A N+ G + RPE E+I L E Sbjct: 782 TLIIKTTVRDDDDTYKCVASNQVG-KVTCRGDLKVTEKMFPPEITRPERTEKIVLLE 837 Score = 47.2 bits (107), Expect = 3e-04 Identities = 36/109 (33%), Positives = 50/109 (45%), Gaps = 5/109 (4%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 KPV V+PLSN V E E ++ G+P RV W+H + G+ +K D G Sbjct: 1735 KPVIVKPLSNLQ-VEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791 Query: 1236 ALDIIHATSA--DTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282 +I S D+G Y AVN G A + A + V R T ++E Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDE 1840 Score = 47.2 bits (107), Expect = 3e-04 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 3/97 (3%) Query: 1843 APRFI-TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 APRF T L EG + I P P V W +G V+ S + Sbjct: 2415 APRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPT--VTWMKDGNVISSSNGVSLRQRGES 2472 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938 +L I+ V EDSG YTC+A+++LG+A S L V++ Sbjct: 2473 YSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEA 2509 Score = 47.2 bits (107), Expect = 3e-04 Identities = 26/91 (28%), Positives = 41/91 (45%) Query: 776 LQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHL 835 L +L LQ F+ V+ ++EW KDGR T F+ ++L + Sbjct: 2520 LSELPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNA 2579 Query: 836 RAEDAGSYTVRAVNKLGEAISTASIRVAARS 866 +DAG Y NK GE+ S+A I + ++ Sbjct: 2580 TLKDAGRYQCIVTNKFGESSSSADISITQKT 2610 Score = 46.8 bits (106), Expect = 4e-04 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 2/97 (2%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F M+ ++V E F+ R+ G P +VEW +N I+ R + + +L Sbjct: 123 PEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSL 180 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807 + D+ TY C A +E G++ L V+ K S Sbjct: 181 IIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTS 217 Score = 46.8 bits (106), Expect = 4e-04 Identities = 50/204 (24%), Positives = 79/204 (38%), Gaps = 35/204 (17%) Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446 NI EG R+ G P +++W +++K I+ + R+T T + +S + ED Sbjct: 229 NITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDS 286 Query: 2447 GVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFE 2506 G Y C A + G + +E P+G+ +F Sbjct: 287 GRYKCTAKSEHG--------TASKEFDVNVEKAKPKGVAP-----------------KFT 321 Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566 KP+ T E+ E + A E V G+P+ EW LK R + D V Sbjct: 322 KPLETL------EIMEKETARLECTVT--GEPAPTTEWLKGDQPLKETQRIKIERDKDSV 373 Query: 2567 TLDINSVVANDAGLYMCKAINRAG 2590 L++ V +D LY A N +G Sbjct: 374 VLEVRHVELDDEALYKVVAKNESG 397 Score = 46.8 bits (106), Expect = 4e-04 Identities = 66/273 (24%), Positives = 99/273 (36%), Gaps = 24/273 (8%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP F + L+E + LE V + P ++ W K+ LT R+ Sbjct: 511 APEFAEEEATQLTLIEDDDMTLELHVTGKPKP--EVHWTKDNKPLTEDDRIIIDHKGDSC 568 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXX 2760 + I ++ +DSG Y C+A N G T + +E ++ G S IG++ Sbjct: 569 IVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEVL-FVAGIS------QVIGSIRFIV 621 Query: 2761 XXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGT 2820 L + EG+ + C + P EWF + P+ G Sbjct: 622 LAKKPAGEAPE----ITESLQEMEELEGNPVTLTCKFTGTPAPV--AEWFKASTPVRDGR 675 Query: 2821 RYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQG 2880 RYK T + +L I T +D+ Y N GS + +R T F Sbjct: 676 RYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTK----- 730 Query: 2881 KAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEW 2913 K VE+ +EARL V T P EW Sbjct: 731 KLKPVEVEEGQEARL----DVRVVGTPTPNVEW 759 Score = 46.8 bits (106), Expect = 4e-04 Identities = 56/250 (22%), Positives = 88/250 (35%), Gaps = 34/250 (13%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130 TG + W + K + RI + +++I+ DSGTY C A NK G Sbjct: 537 TGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTR 596 Query: 3131 ----QAEI-----------SVK-LECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174 E+ S++ + K G+ P T +Q +E L +G C Sbjct: 597 TFIVNVEVLFVAGISQVIGSIRFIVLAKKPAGEAPEITESLQEMEEL-EGNPVTLTCKFT 655 Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--E 3232 P EW+ P+R R K + L I T+ D+ EY N G + Sbjct: 656 GTPAP--VAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVK 713 Query: 3233 DFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVT 3292 TR I ++PD K++ +E +G + + P + T Sbjct: 714 SETRVRITAL---------VRPDFTKKLKPVEVEEGQEARLDVRVVGTPTPNVEWFCGTT 764 Query: 3293 KLVEGQSAHF 3302 KL + F Sbjct: 765 KLTDTDRYEF 774 Score = 46.8 bits (106), Expect = 4e-04 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 7/107 (6%) Query: 902 VPESTQKPEFK-TPIKDQISIKEGGFAHFEARLEPI--GDSTLRVEWLKDGRPVEASSRI 958 V E P F T + ++ +EG FE I G V W+KDG + +S+ + Sbjct: 2409 VQEREHAPRFDGTDLGQSVTAQEG----FELNKTFIIRGKPRPTVTWMKDGNVISSSNGV 2464 Query: 959 TTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005 + +L I VT D+G+YTC+A +++G+A+ S +L + K Sbjct: 2465 SLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEAPK 2511 Score = 46.8 bits (106), Expect = 4e-04 Identities = 24/67 (35%), Positives = 39/67 (58%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P+ V W+++G I +SN ++ +L + V EDSG YTC+A++ LG+A S Sbjct: 2443 GKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQS 2502 Query: 1798 STLFVQS 1804 L V++ Sbjct: 2503 FDLKVEA 2509 Score = 46.8 bits (106), Expect = 4e-04 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750 K PP F E+ + V EG F + V +I+W +GR F G D Sbjct: 2513 KEEPPSFLSELPP-LQVREG--FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDG 2569 Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 I L +DAG Y C TNK+G ++++A I+ + K Sbjct: 2570 RNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609 Score = 46.8 bits (106), Expect = 4e-04 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Query: 2648 LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK----STFDFGLVTLS 2703 LKS + + GQ + VE P K++W+ G +T G R K + D + TL Sbjct: 2619 LKSIESVEGGQARF---DVEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLI 2675 Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 I SL+ DSG Y C ATN G + +K+++ Sbjct: 2676 IESLKYTDSGTYKCIATNEGGVTTIKSDLKVKE 2708 Score = 46.4 bits (105), Expect = 6e-04 Identities = 62/276 (22%), Positives = 102/276 (36%), Gaps = 25/276 (9%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 + E PEF Q+++ E E L G V W KD +P+ RI Sbjct: 505 IEELLVAPEFAEEEATQLTLIEDDDMTLE--LHVTGKPKPEVHWTKDNKPLTEDDRIIID 562 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021 + I +VT +D+G Y C A N G T T + +++ + + I+ Sbjct: 563 HKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTR----TFIVNVEVLFVAGISQVIGSIR 618 Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081 ++ A K E +IT+ + + L+G N + + F P EW+ Sbjct: 619 FIVLA---KKPAGEAPEITESLQEMEELEG-NPVT--LTCKFTGTPAP------VAEWFK 666 Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141 + R + L I R +D+ Y VV RN G S+ ETR I Sbjct: 667 ASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG------SVKSETRVRI 720 Query: 1142 DTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKP 1177 T+ + +K + +E + E + + P Sbjct: 721 -TALVRPDFTKKLKPVEVEEGQEARLDVRVVGTPTP 755 Score = 46.4 bits (105), Expect = 6e-04 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P FT +K + V E Q A + R+ VG P VEW + ++R + + L Sbjct: 726 PDFTKKLKPVEVEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTL 783 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 +K +D TY C A N++G+ L V K Sbjct: 784 IIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK 818 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 P+ E PK + +Q + L EG A ++ P VEWF K+ R + + Sbjct: 1085 PTGEAPKVVDALQPLEAL-EGDEAKLVCKIT--GSPTPTVEWFKEKAKVVDVRRTKMEYT 1141 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 + L I E+ G Y+CVA N G ST A L Sbjct: 1142 DDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATL 1177 Score = 46.4 bits (105), Expect = 6e-04 Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 2/78 (2%) Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG--LVTLSINSLRNDDSGIYTCKAT 2720 +A+ + N K+EW + G + K + + G L +L + L+++D G YTC A+ Sbjct: 2044 QARFDVHFTGNPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVAS 2103 Query: 2721 NLLGEAVSTASIKIEDRH 2738 N G+A A++ ++D+H Sbjct: 2104 NESGDATLHANLNVKDKH 2121 Score = 46.4 bits (105), Expect = 6e-04 Identities = 22/68 (32%), Positives = 36/68 (52%) Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728 R +P + W+K+G L R+ + + L++ DD+GIY C+A N LG A Sbjct: 2150 RGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASR 2209 Query: 2729 TASIKIED 2736 T +K+E+ Sbjct: 2210 TVMVKVEE 2217 Score = 46.4 bits (105), Expect = 6e-04 Identities = 46/188 (24%), Positives = 78/188 (41%), Gaps = 36/188 (19%) Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330 +P + +Y +G LQ R I+ + L + VP+DAG Y +A N LG Sbjct: 2152 NPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLG------ 2205 Query: 2331 SMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390 TA ++ + K+ EL K +P +T PV I+E Sbjct: 2206 ----TASRTV---------MVKVEEL------KGRGVPSFITGLFPV---------QIKE 2237 Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450 G CR+ G P + WFR+ + +R+ +++ ++ + ++ D G+Y Sbjct: 2238 GDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYK 2295 Query: 2451 CRASNLLG 2458 C A+N G Sbjct: 2296 CTATNSQG 2303 Score = 46.4 bits (105), Expect = 6e-04 Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 9/109 (8%) Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV----H 3745 +K P +K +I+ EGG FD VE P ++DW+H G G R Sbjct: 2608 QKTRKPEAIAPLK-SIESVEGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQS 2664 Query: 3746 TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794 T D L I+ + D+G Y C ATN+ G TT K K + Sbjct: 2665 TDGDRPVYTLIIESLKYTDSGTYKCIATNEGG--VTTIKSDLKVKEPFI 2711 Score = 46.4 bits (105), Expect = 6e-04 Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK----TTYDF 2032 KP+ P+K+ E EG + ++ P +V+WY G + G R+K T D Sbjct: 2612 KPEAIAPLKSIESVEGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYKIIQSTDGDR 2669 Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 L I D+GTY C ATN G S +KV Sbjct: 2670 PVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706 Score = 46.0 bits (104), Expect = 8e-04 Identities = 28/129 (21%), Positives = 56/129 (43%), Gaps = 5/129 (3%) Query: 3678 TLHKREEITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735 T K ++ +E KP P+FT + + +++ E +C V G+P +W Sbjct: 299 TASKEFDVNVEKAKPKGVAPKFTKPL-ETLEIMEKETARLECTV--TGEPAPTTEWLKGD 355 Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795 +P R+ D + L++ ++ D Y A N+ G AT+ A++ + + Sbjct: 356 QPLKETQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPF 415 Query: 3796 ESQLPQGMS 3804 + PQ ++ Sbjct: 416 FKKTPQNVT 424 Score = 46.0 bits (104), Expect = 8e-04 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 6/115 (5%) Query: 2348 EGLEKI-RELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDP 2406 E L K+ + ES E+ ++P F + QN+ + EG D R+ +P Sbjct: 385 EALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNV-TVLEGDEIRLDARVGGKPEP 443 Query: 2407 TLKVEWFRNEKLIEDSSR--ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 T V+WF+ ++ + + R I + S+ I + + D GVY+C+A+N G+ Sbjct: 444 T--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGK 496 Score = 46.0 bits (104), Expect = 8e-04 Identities = 37/126 (29%), Positives = 51/126 (40%), Gaps = 4/126 (3%) Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895 V + P F +L P ++ EGQ A + R+ P PN VEW+ L RY Sbjct: 718 VRITALVRPDFTKKLK-PVEVEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRYEF 774 Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955 + L I T +D Y C A N +G+ L V K ++ E EKI Sbjct: 775 IEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKMFPPEITRPERT-EKI 833 Query: 1956 QYLEDD 1961 LE + Sbjct: 834 VLLEKE 839 Score = 46.0 bits (104), Expect = 8e-04 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P FT LK + + EGQ L+ +V PN +EWF LT R + + T Sbjct: 726 PDFTKKLKPVE-VEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRYEFIEEGDSYT 782 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 L I + DD Y C A+N +G+ +K+ ++ Sbjct: 783 LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK 818 Score = 46.0 bits (104), Expect = 8e-04 Identities = 23/91 (25%), Positives = 42/91 (46%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P E+ ++ + G A F ++ G PTP V W + ++ + + ++ + + + G L Sbjct: 1477 PKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQL 1536 Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162 +I+ P D G Y C N GE +Q Sbjct: 1537 VIEDAKPEDSGVYKCVVFNDIGETQTKAKLQ 1567 Score = 46.0 bits (104), Expect = 8e-04 Identities = 21/62 (33%), Positives = 33/62 (53%) Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161 VEE K R P F++ V ++EG+ CRV+G PKP + W + + +R +Y Sbjct: 2215 VEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASY 2274 Query: 4162 DG 4163 +G Sbjct: 2275 EG 2276 Score = 46.0 bits (104), Expect = 8e-04 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P F LK + L E + L+ ++ P +E++K+ + R K D + Sbjct: 2320 PTFVVGLKETEGL-ESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 L I +LR +D+G Y C TNLLG S A I++++R Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412 Score = 46.0 bits (104), Expect = 8e-04 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 5/103 (4%) Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877 +APK + PP F++++ V E + +V +D K IEW ++G+ G Sbjct: 2508 EAPK---VKEEPPSFLSELPPLQVREGFEFKLIFKVVTTKDSK--IEWRKDGRAFTPGGN 2562 Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920 +D ++L +D+G Y C N FGE + A IS Sbjct: 2563 SEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADIS 2605 Score = 46.0 bits (104), Expect = 8e-04 Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 9/155 (5%) Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764 +V + P F + ++V E +++ D K +EW ++G D Sbjct: 2511 KVKEEPPSFLSELPPLQVREGFEFKLIFKVVTTKDSK--IEWRKDGRAFTPGGNSEFSFD 2568 Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824 + L K +D+G Y C N+ GE+ +S+ + + K ++ A+ ++ + Sbjct: 2569 GRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK------TRKPEAIAPLKSI 2622 Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859 E Q R DVE++ P+ + +G TK++ G Sbjct: 2623 ESVEGGQARFDVEMSAFPLPK-VDWYHGGTKITHG 2656 Score = 45.6 bits (103), Expect = 0.001 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 4/113 (3%) Query: 1295 ARRTKQVREDITVMQA--PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP 1352 A RT V+ ++ + P L + G + L C++ G +++W + KP Sbjct: 1363 ATRTFDVQVEVPKPRGSKPSLEAELKPVTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKP 1420 Query: 1353 IKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 +K R P Y+ + L ED Y A N+LG TS L V K Sbjct: 1421 LKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473 Score = 45.6 bits (103), Expect = 0.001 Identities = 57/297 (19%), Positives = 108/297 (36%), Gaps = 15/297 (5%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 S P E K G + K K+ G P P + W + PL + Y+ +T Sbjct: 1379 SKPSLEAELKPVTVTAGEDTKLVCKISGKPQPKIDWMKDDKPLKPDKRVLPTYDGET--C 1436 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXY-RHVSETV 186 L + DE EY A+N+ G S + + +G T Sbjct: 1437 VLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEKGAAPKIEKPLQDVKVDAGKKATF 1496 Query: 187 EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRES-----IT 241 + GT E + + + G DD K F+ ++ + +S + Sbjct: 1497 NTQVSGTPTPEVEWFK-GESIVEDKGR-FMIIDDAKEGVFQL-VIEDAKPEDSGVYKCVV 1553 Query: 242 KRYVGESDVQISTEIDR-SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRP-RVTW 299 +GE+ + ++D + P + K+ +K + E + V++ G P +V W Sbjct: 1554 FNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYVPDKVLW 1613 Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356 FK+ + + +I + L + + D+GHY + G +++ + V+ Sbjct: 1614 FKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLIIVK 1670 Score = 45.6 bits (103), Expect = 0.001 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 2/75 (2%) Query: 2665 QVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG--LVTLSINSLRNDDSGIYTCKATNL 2722 +V+ +P ++ W+ L G K D G TL +N + DSG+Y C A N Sbjct: 1756 EVQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNE 1815 Query: 2723 LGEAVSTASIKIEDR 2737 G+A+S A++++ R Sbjct: 1816 AGKAISQATLEVTGR 1830 Score = 45.6 bits (103), Expect = 0.001 Identities = 46/163 (28%), Positives = 62/163 (38%), Gaps = 14/163 (8%) Query: 3046 RPPEFTTVFKDIVDISEGQIAH-YEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 R PE K I + GQ E S P ++W++ G I R + + + Sbjct: 2611 RKPEAIAPLKSIESVEGGQARFDVEMSAFPLPK----VDWYHGGTKITHGGRYKIIQSTD 2666 Query: 3105 ----MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFT-THIQNIE 3159 + L I K TDSGTY C ATN+ G I L+ K P F I Sbjct: 2667 GDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV--KEPFIAPEFEGKDITAPM 2724 Query: 3160 GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202 KDGQ + P I WY +G+ + S R+ S Sbjct: 2725 VYKDGQDIKVSFKI--KSRPKPIIAWYKDGKALTSSKRVTLTS 2765 Score = 45.2 bits (102), Expect = 0.001 Identities = 29/114 (25%), Positives = 54/114 (47%), Gaps = 3/114 (2%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E + ++T ++P+F + +Q L ++ EG F+ ++ PT +VEW+K+ I R Sbjct: 113 EVLVKETLRKPEFKQKMQPL-QVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRF 169 Query: 820 TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLG 873 I SL I R DA +Y A ++ G++ + V +++ G Sbjct: 170 EIIDEEDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFG 223 Score = 45.2 bits (102), Expect = 0.001 Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 2/85 (2%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712 +++EG V + +++ + P K+EWFKN + R + + L +L I+ R D+ Sbjct: 133 QVLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDA 190 Query: 2713 GIYTCKATNLLGEAVSTASIKIEDR 2737 Y C AT+ G++ + ++++ Sbjct: 191 DTYKCIATSEAGKSTCIVELSVKEK 215 Score = 45.2 bits (102), Expect = 0.001 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EGD + F+ ++ PT K+EWF N + + R++ + SL I T D+ Y Sbjct: 136 EGDEVRFDVRIDGK--PTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADTY 193 Query: 2847 TCKATNSKGSAT 2858 C AT+ G +T Sbjct: 194 KCIATSEAGKST 205 Score = 45.2 bits (102), Expect = 0.001 Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 5/156 (3%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E T PE I+I EG R+ G ++W KD +P++ + R+TT Sbjct: 212 VKEKTSAPEVFGDTAP-INITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTT 268 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021 L + D+G Y C A + G A+ ++ + K + LE ++ Sbjct: 269 TKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLE 328 Query: 1022 YLE-DASRYS-KRTEEEVKITQKPRFLGPLKGTNKI 1055 +E + +R T E T+ + PLK T +I Sbjct: 329 IMEKETARLECTVTGEPAPTTEWLKGDQPLKETQRI 364 Score = 45.2 bits (102), Expect = 0.001 Identities = 35/125 (28%), Positives = 54/125 (43%), Gaps = 3/125 (2%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP+ I EG + L R++ G ++W + KPIK R + D Sbjct: 218 APEVFGDTAPINITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECV 275 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DTS 1428 L L PEDSG Y C A ++ G A + V K + + LE ++ +E +T+ Sbjct: 276 LVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKETA 335 Query: 1429 RYKKT 1433 R + T Sbjct: 336 RLECT 340 Score = 45.2 bits (102), Expect = 0.001 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F L + +EG + V + PT +EWF L RY+ + +L I Sbjct: 728 FTKKLKPVEVEEGQEARLDVRVVGT--PTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLII 785 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866 T +D Y C A+N G T G L+ T Sbjct: 786 KTTVRDDDDTYKCVASNQVGKVTCRGDLKVT 816 Score = 45.2 bits (102), Expect = 0.001 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 2/95 (2%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P+ ++ E EG L +T PT VEW+ V R K Y Sbjct: 1088 EAPKVVDALQPLEALEGDEAKLVCKIT--GSPTPTVEWFKEKAKVVDVRRTKMEYTDDVA 1145 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 L I ED G Y C A N GEA T++++ ++ Sbjct: 1146 TLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHIN 1180 Score = 45.2 bits (102), Expect = 0.001 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 3/97 (3%) Query: 2105 PGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF 2164 P +P F T L +E + E A FE R P ++WF KI R+R + Sbjct: 1181 PVVKPDFKTKLKPME-VTEESVAKFEVRSTGFPQPE--VEWFLGSTKIEDSGRFRVVSEQ 1237 Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 L I +D+GTY C N+ G A + LKV Sbjct: 1238 DRHELIISDVKVKDAGTYKCTLANQAGTAYSRADLKV 1274 Score = 45.2 bits (102), Expect = 0.001 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 3/98 (3%) Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234 SKP L P V+ G++ L C++ G P +++W + + + R YD Sbjct: 1379 SKPSLEAELK-PVTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDKRVLPTYDGET 1435 Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 L A D EY V A N LGS TSA + V E+ Sbjct: 1436 CVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473 Score = 45.2 bits (102), Expect = 0.001 Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 3/88 (3%) Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430 V + P F L+ ++ + EG C+L PT EW RN + +R+ + D Sbjct: 1927 VDGKAPRFVSELRPVE-VFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFD 1983 Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458 Y ++ + + ED+G Y C A N+ G Sbjct: 1984 GRYSTLKFLNAKIEDQGTYSCLAKNVFG 2011 Score = 45.2 bits (102), Expect = 0.001 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 1843 APRFITQLNG-PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 AP F+ G P + G+ + I P P+ V WY +G LQ R S+ + Sbjct: 2123 APMFVEDDTGEPITVEAGKELNVIMNIRGNPRPD--VNWYKDGSFLQQTGRMGISSRWDS 2180 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 L + +D+G Y C+A N LG A ++ + V+ Sbjct: 2181 YRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVE 2216 Score = 45.2 bits (102), Expect = 0.001 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 5/137 (3%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMV--DEVTTQA-PICTTSLKNVEIKEGQRAHFE 1598 + ++ ++AG+ + + RT MV +E+ + P T L V+IKEG + Sbjct: 2185 VFKAVPDDAGIYRCEAKNKLGTASRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLV 2244 Query: 1599 RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINAL 1658 R+ T + W+ +N P+ + +R + AL++ D+G Y C A N+ Sbjct: 2245 CRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQ 2302 Query: 1659 GEAVTSGIAIVHSKKSI 1675 G +S + K +I Sbjct: 2303 GSTSSSAEVTIKRKDAI 2319 Score = 45.2 bits (102), Expect = 0.001 Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 4/108 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P FI L + +++EG +++ PT + W++D P+ +R+ + + + Sbjct: 2224 PSFITGLFPV-QIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSA 2280 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV-TADLGIPE 876 L + ++ DAG Y A N G S+A + + + + T +G+ E Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKE 2328 Score = 44.8 bits (101), Expect = 0.002 Identities = 21/53 (39%), Positives = 27/53 (50%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163 P F VTV EGE RV G P P V W+++G + + R K T+DG Sbjct: 27 PEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKVQDDHRIKTTFDG 79 Score = 44.8 bits (101), Expect = 0.002 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 3/108 (2%) Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492 T+++ + KP F + + ++ V+EG V F+ +++ KVEWFKN + R Sbjct: 112 TEVLVKETLRKPEFKQKMQPLQ-VLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGR 168 Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540 F I + +L I D D+ Y C A + G L+ + T Sbjct: 169 FEIIDEEDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKT 216 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/108 (24%), Positives = 50/108 (46%) Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892 R D++V P IT+ K+ + + +P V+W+ +GK ++ R Sbjct: 810 RGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSR 869 Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 L+I T ED+G YTC+A N +G + ++I + +++ + Sbjct: 870 LNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIEASK 917 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 IV ++G++I + P +K W+ + KPL G R + + ED Sbjct: 1291 IVVRQGEDIDIGAQITAKPKPNVK--WYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPED 1348 Query: 2843 SGIYTCKATNSKGSAT 2858 +G+Y C+ATN+ G AT Sbjct: 1349 TGMYKCEATNAVGKAT 1364 Score = 44.8 bits (101), Expect = 0.002 Identities = 87/379 (22%), Positives = 141/379 (37%), Gaps = 67/379 (17%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF--GF 1234 P +PL + V GK ++ G PT VEWF V RF D G Sbjct: 1477 PKIEKPLQDVK-VDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533 Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDA 1294 L I A D+G Y N +G T A ++V + +++ Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQV----------------DAVEVAPKT 1577 Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354 ++ + E ITV++ + ++ V+G V +V WF + P+K Sbjct: 1578 DKKLDEKEEPITVLEHQEVDMSVK----VKGKYV------------PDKVLWFKDDTPVK 1621 Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV----------IA 1404 T + E L L +D+G Y C++T +LG +++ + V IA Sbjct: 1622 TNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIA 1681 Query: 1405 KKDLILESQHPSG---LEKIQYLEDTSRYK------------KTDIIDESVTIKPRFVTR 1449 K + E+ H + K +D YK ++I +KP + + Sbjct: 1682 KDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAVKP-VIVK 1740 Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDII-- 1507 P S V E FE ++ + +V W+ + G ++ + D G +I Sbjct: 1741 PLSNLQVEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVN 1798 Query: 1508 DLIAEDSGIYTCRAVNLVG 1526 D DSG+Y C AVN G Sbjct: 1799 DSQRHDSGVYKCVAVNEAG 1817 Score = 44.4 bits (100), Expect = 0.002 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 2/99 (2%) Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034 + KP+F + ++ +V EG V + + PT +VEW+ N + RF+ + Sbjct: 120 LRKPEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDL 177 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 +L I D TY C AT+ G++ + V K+ Sbjct: 178 YSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKT 216 Score = 44.4 bits (100), Expect = 0.002 Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 7/139 (5%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM--GFV 3887 P F ++ TV E + +R + RV K +P ++W++ + + R+ V D Sbjct: 414 PFFKKTPQNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLF 471 Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL---PDIILQNQVPRGMKRSEALT 3944 SL I DSG YIC+A ND G+ +A I ++L P+ + + + +T Sbjct: 472 SLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMT 531 Query: 3945 QMEATIKKYTSEVYLTEDD 3963 K EV+ T+D+ Sbjct: 532 LELHVTGKPKPEVHWTKDN 550 Score = 44.4 bits (100), Expect = 0.002 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 3/98 (3%) Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202 K G+ P+ +Q +E L +G A C + P +EW+ + R K Sbjct: 1084 KPTGEAPKVVDALQPLEAL-EGDEAKLVCKIT--GSPTPTVEWFKEKAKVVDVRRTKMEY 1140 Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240 L I T+ D G Y C A N +GE T AT++ Sbjct: 1141 TDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLH 1178 Score = 44.4 bits (100), Expect = 0.002 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 7/98 (7%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+ I I+D+ EG A F+ +P KVEW + +++ HG +Y+ + G + Sbjct: 2028 PQPIGMIRDIEGY-EGGQARFDVHFT--GNP--KVEWLHGEEQIIHGEKYKISENPGEYL 2082 Query: 3342 LDILY--CYEENSGEYECVATNKLGRDSTKANLKCTSK 3377 ++ E+ G Y CVA+N+ G + ANL K Sbjct: 2083 YSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120 Score = 44.4 bits (100), Expect = 0.002 Identities = 91/377 (24%), Positives = 140/377 (37%), Gaps = 74/377 (19%) Query: 2216 GLEKIRQLEAQGH-STRIEVE-EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPN 2273 GL K +QG S+ EV + K + P FV L+ T + +++ V+ P Sbjct: 2292 GLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGL---ESSDMRLDVKIGGFPR 2348 Query: 2274 LRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMT 2333 +EFY + + + R I D SL I + PEDAG Y N LG TS Sbjct: 2349 PTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETS----- 2403 Query: 2334 VTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQT 2393 E + +++E E A F ++ + VT Q + + +T Sbjct: 2404 --------------EAVIRVQEREHAPRFDGTDLGQSVTAQ-----------EGFELNKT 2438 Query: 2394 AHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453 I G P V W ++ +I S+ ++ S+ I V ED G Y C+A Sbjct: 2439 ------FIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQA 2492 Query: 2454 SNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQV 2513 + LG+ L+ + P K++ E+P SE P Sbjct: 2493 VSSLGK----------ASQSFDLKVEAP----KVK--EEPPSFLSELP------------ 2524 Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSV 2573 P ++ EG +VV D + EW +G G + D +TL + Sbjct: 2525 ---PLQVREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNA 2579 Query: 2574 VANDAGLYMCKAINRAG 2590 DAG Y C N+ G Sbjct: 2580 TLKDAGRYQCIVTNKFG 2596 Score = 44.4 bits (100), Expect = 0.002 Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 3/89 (3%) Query: 778 DLGELQEGRNAHFEAQLTPV--SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHL 835 DLG+ + FE T + P V W KDG I++S+ ++ SL I+ + Sbjct: 2422 DLGQSVTAQEG-FELNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKV 2480 Query: 836 RAEDAGSYTVRAVNKLGEAISTASIRVAA 864 ED+G+YT +AV+ LG+A + ++V A Sbjct: 2481 TKEDSGNYTCQAVSSLGKASQSFDLKVEA 2509 Score = 44.4 bits (100), Expect = 0.002 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 7/103 (6%) Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR---- 3470 +K + P PL +IE++ EG A F+ ++ P KV+WY G + G R++ Sbjct: 2608 QKTRKPEAIAPLKSIESV-EGGQARFDVEMSAFPLP--KVDWYHGGTKITHGGRYKIIQS 2664 Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 T D L I DSG Y C A N G + +KV+ Sbjct: 2665 TDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVK 2707 Score = 44.0 bits (99), Expect = 0.003 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 5/96 (5%) Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166 ++P F + L+ L EGD F+ R++ P ++WF N KI R+ + Sbjct: 121 RKPEFKQKMQPLQVL-EGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDL 177 Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202 +L I T D+ TY C AT++ G+ +TC ++++ Sbjct: 178 YSLIIDDTRLSDADTYKCIATSEAGK--STCIVELS 211 Score = 44.0 bits (99), Expect = 0.003 Identities = 59/265 (22%), Positives = 98/265 (36%), Gaps = 25/265 (9%) Query: 3667 SGTESIQKLEETLHKREEITIE-DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDP 3725 SG Q +T E I+ +E P F E + + E + + V G P Sbjct: 483 SGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLELHV--TGKP 540 Query: 3726 TMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 + W + +P R+ + +DI + D+G Y C A NK G T T + Sbjct: 541 KPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIV 600 Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESE 3845 +++ + + Q + + L + +AP+ IT+ +EE E Sbjct: 601 NV----EVLFVAGISQVIGSIRFIVLAKKPAGEAPE-----------ITE-SLQEMEELE 644 Query: 3846 G--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYI 3903 G V C+ P EW++ + G RY+ +L I +D+ EY Sbjct: 645 GNPVTLTCKFTGTPAPV--AEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQ 702 Query: 3904 CRAVNDFG--EDFTKATISCKKLPD 3926 ND G + T+ I+ PD Sbjct: 703 VVIRNDIGSVKSETRVRITALVRPD 727 Score = 44.0 bits (99), Expect = 0.003 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 3/96 (3%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 P FT L +E + EG+ A + R+ T PN VEW+ L R+ + Sbjct: 726 PDFTKKLKPVE-VEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRYEFIEEGDSYT 782 Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 L I T +D Y C A N G+ +KV K Sbjct: 783 LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK 818 Score = 44.0 bits (99), Expect = 0.003 Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 3/96 (3%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 P F L +E + E A FE R T P +VEW+ ++ RFR + Sbjct: 1185 PDFKTKLKPME-VTEESVAKFEVRSTGFPQP--EVEWFLGSTKIEDSGRFRVVSEQDRHE 1241 Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 L IS +D+G Y C N G A + A +KV+ K Sbjct: 1242 LIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK 1277 Score = 44.0 bits (99), Expect = 0.003 Identities = 54/231 (23%), Positives = 92/231 (39%), Gaps = 34/231 (14%) Query: 942 RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 +V W KD PV+ ++ LT+ ++ DAGHY C + +G TT + I Sbjct: 1610 KVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLG--TTISTFLI 1667 Query: 1002 VTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKI------ 1055 + K + + + + + K ++L++A T + Q+ + + K TNK+ Sbjct: 1668 IVKVEWLKDDKP---IAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCG 1724 Query: 1056 ---VEGQSAHFEARVEPQSDLTMT------------------VEWYFNGKQITSANRIQT 1094 + + A V+P S+L + V WY ++ + Sbjct: 1725 ANLIVNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKM 1784 Query: 1095 YHDFGY--VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143 D G L + + DSGVY VA N AG+A A++ V R T Sbjct: 1785 LEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPT 1835 Score = 44.0 bits (99), Expect = 0.003 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 2/96 (2%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G P F + + + E + C+L ++ EW NG P+ +RV+ D + Sbjct: 1929 GKAPRFVSELRPVEVFEGNEVSLVCKLSA--EAKPTFEWSRNGSPVRLDNRVQASFDGRY 1986 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 L+ D G Y+C A N G A+ KL VK Sbjct: 1987 STLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVK 2022 Score = 44.0 bits (99), Expect = 0.003 Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 3/149 (2%) Query: 2875 TQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQ 2934 T+ G +AV +A + + P + P ++ + Q+ EG L + Sbjct: 2481 TKEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPL-QVREGFEFKLIFK 2539 Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 V D KIEW +G+ G + + D +TL + +D+G Y C NK GE Sbjct: 2540 VVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGE 2597 Query: 2995 AFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023 + +S+ + T K E K E +E Sbjct: 2598 SSSSADISITQKTRKPEAIAPLKSIESVE 2626 Score = 43.6 bits (98), Expect = 0.004 Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 3/103 (2%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 +E +PK P+F L T + E +TA EC V +P E+ + L+ R Sbjct: 308 VEKAKPKGVAPKFTKPLE-TLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRI 364 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 I D V L+++H +D Y V A N G TS + V Sbjct: 365 KIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLV 407 Score = 43.6 bits (98), Expect = 0.004 Identities = 37/120 (30%), Positives = 54/120 (45%), Gaps = 7/120 (5%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FG 1233 KP F + N V EG I L+ R+ +PT V+WF + V RF D Sbjct: 413 KPFFKKTPQNVT-VLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGD 469 Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLED 1293 +L I +A D+G Y +A N G A A +++ E +V E+ Q+ L+ED Sbjct: 470 LFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEEL--LVAPEFAEEEATQLTLIED 527 Score = 43.6 bits (98), Expect = 0.004 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 4/94 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--RFGYI 694 P F ++VT +EG +I + R+ +PT ++W K Q + RF + Sbjct: 414 PFFKKTPQNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLF 471 Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 SL + + DSG Y C+A + TG A +A + + Sbjct: 472 SLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 505 Score = 43.6 bits (98), Expect = 0.004 Identities = 22/74 (29%), Positives = 38/74 (51%) Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855 NV +P ++WF + KP+ +R +L+I T ED+G YTC+A N G Sbjct: 844 NVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG 903 Query: 2856 SATTSGSLRCTGDK 2869 +++T+ ++ K Sbjct: 904 TSSTTIDVQIEASK 917 Score = 43.6 bits (98), Expect = 0.004 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 3/95 (3%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH---F 4167 PV V + VEE RF ++ G+PKPRV W ++ G+ YK+ D H Sbjct: 1736 PVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTL 1795 Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202 + ++++D+G + + L+V R Sbjct: 1796 IVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830 Score = 43.6 bits (98), Expect = 0.004 Identities = 48/194 (24%), Positives = 81/194 (41%), Gaps = 20/194 (10%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV---- 3100 G P+ + +DI GQ A ++ TG+ +EW + + I + + Sbjct: 2025 GNRPQPIGMIRDIEGYEGGQ-ARFDVHF--TGNPK--VEWLHGEEQIIHGEKYKISENPG 2079 Query: 3101 -YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159 Y + +VV ++ K D G Y+C A+N+ G A + L DK P F +++ Sbjct: 2080 EYLYSLVVGDL---KHEDGGRYTCVASNESGDATLHANLNVKDKHIA--PMF---VEDDT 2131 Query: 3160 GLKDGQSAHFECTVVPV--DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNH 3217 G A E V+ +P + WY +G ++ + R+ S + L + Sbjct: 2132 GEPITVEAGKELNVIMNIRGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPD 2191 Query: 3218 DSGEYVCRAYNKYG 3231 D+G Y C A NK G Sbjct: 2192 DAGIYRCEAKNKLG 2205 Score = 43.6 bits (98), Expect = 0.004 Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P F + ++ EG L ++ PT + W+ + PV +R +Y+ AL Sbjct: 2224 PSFITGLFPVQIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSAL 2281 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGL 2075 ++ D G Y C ATN+ G +++ V + K + Sbjct: 2282 ELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319 Score = 43.2 bits (97), Expect = 0.005 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 2/79 (2%) Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982 L+E + L + + PD+K W+ +GK + Q SR + TL++ D+G Sbjct: 835 LLEKEELVINVTILGNPRPDVK--WFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAG 892 Query: 2983 IYTCKAYNKRGEAFTSSTV 3001 YTC+A NK G + T+ V Sbjct: 893 SYTCEAQNKMGTSSTTIDV 911 Score = 43.2 bits (97), Expect = 0.005 Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 8/154 (5%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P+F T + ++E S A FE R VEWF + R + +++ L Sbjct: 1185 PDFKTKLKPMEVTEESVAKFEVR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHEL 1242 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ---GIILEPQLPSHFKSGTESIQK 3674 I V +DAG Y C N+ G A L+VK + + + P + G + Sbjct: 1243 IISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIG 1302 Query: 3675 LEETLHKREEIT-IEDEKP--NPPRFTVEIKDNI 3705 + T + + +D KP + PR T+ +D++ Sbjct: 1303 AQITAKPKPNVKWYKDGKPLRDGPRTTIRARDDL 1336 Score = 43.2 bits (97), Expect = 0.005 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 5/109 (4%) Query: 3684 EITIEDEKP--NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 ++ +E KP + P E+K + V G C++ G P +IDW + +P Sbjct: 1368 DVQVEVPKPRGSKPSLEAELKP-VTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPD 1424 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 RV D L D EY A N+ GS +T+A++ + K Sbjct: 1425 KRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473 Score = 43.2 bits (97), Expect = 0.005 Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 5/106 (4%) Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 I + + +P ++PL +L +++E FE Q+ +P RV WY + + Sbjct: 1728 IVNEKAVKPVIVKPLSNL-QVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKM 1784 Query: 822 IFNFGY--VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 + + G +L + + D+G Y AVN+ G+AIS A++ V R Sbjct: 1785 LEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830 Score = 43.2 bits (97), Expect = 0.005 Identities = 53/222 (23%), Positives = 93/222 (41%), Gaps = 43/222 (19%) Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFG--FVALDIMS 1641 ++++E EG +A F+ KVEW H + + G ++ + N G +L + Sbjct: 2034 IRDIEGYEGGQARFDVHFT----GNPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGD 2089 Query: 1642 CLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHS 1701 ED G YTC A N SG A +H+ ++ + +H + Sbjct: 2090 LKHEDGGRYTCVASNE------SGDATLHANLNV--KDKHIAPM---------------F 2126 Query: 1702 AQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTT 1761 +D+ T P+ K++ V N G+P+ V W ++G ++ + R+ Sbjct: 2127 VEDD--TGEPITVEAGKELNVIMNIR----------GNPRPDVNWYKDGSFLQQTGRMGI 2174 Query: 1762 MHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 + L + P+D+G Y C A N+LG A S T+ V+ Sbjct: 2175 SSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTA--SRTVMVK 2214 Score = 43.2 bits (97), Expect = 0.005 Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 2/98 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P FI L V EG K R+ G P I W ++ + +R + + +L Sbjct: 2224 PSFITGLFPVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSAL 2281 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734 ++ + + D+G Y C A ++ G + A + + + I Sbjct: 2282 ELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319 Score = 43.2 bits (97), Expect = 0.005 Identities = 32/92 (34%), Positives = 41/92 (44%), Gaps = 6/92 (6%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK---STH-DFSYVS 2832 I+ L +I EG F+ VE S P K++W+ + G RYK ST D + Sbjct: 2616 IAPLKSIESVEGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGDRPVYT 2673 Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864 L I DSG Y C ATN G T L+ Sbjct: 2674 LIIESLKYTDSGTYKCIATNEGGVTTIKSDLK 2705 Score = 42.7 bits (96), Expect = 0.007 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 6/116 (5%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P F + + + V EG+ + + +++ VEW +G+ V HR + D Sbjct: 27 PEFTKKLQPV-TVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCT 83 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559 L I+ +D G Y C A N VG ++ + + T +R + + ++ +QVLE Sbjct: 84 LKIMPSERDDEGEYKCVATNEVGQATITTEVLVKET---LRKPEFKQKMQPLQVLE 136 Score = 42.7 bits (96), Expect = 0.007 Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 2/104 (1%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E PEF I +++G A++ V+W KDG+P+ R T Sbjct: 1274 VKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQIT--AKPKPNVKWYKDGKPLRDGPRTTIR 1331 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005 + S D G Y C A NA+G+AT + ++ + K Sbjct: 1332 ARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVEVPK 1375 Score = 42.7 bits (96), Expect = 0.007 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF--GF 1634 AP L++V++ G++A F ++ T +VEW+ ++ RF ++ G Sbjct: 1476 APKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533 Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVT 1663 L I PEDSG Y C N +GE T Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQT 1562 Score = 42.7 bits (96), Expect = 0.007 Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 5/111 (4%) Query: 4071 IVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVS--LPDAVTVEEGEWA 4128 IV DSQ +H + K + + + + +E + C P FV + DAV V G+ Sbjct: 1796 IVNDSQ--RHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDEVKDAVYVRGGQEV 1853 Query: 4129 RFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTG 4178 + G P P VMW + + K+ G MY+ I K D+G Sbjct: 1854 SLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSG 1904 Score = 42.7 bits (96), Expect = 0.007 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 3/82 (3%) Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 V W +G I + + + +L ++ V EDSG YTCQA + LG+A S L+V Sbjct: 2449 VTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVE 2508 Query: 1404 AKKDLILESQHPSGLEKIQYLE 1425 A K ++ + PS L ++ L+ Sbjct: 2509 APK---VKEEPPSFLSELPPLQ 2527 Score = 42.7 bits (96), Expect = 0.007 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 8/90 (8%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR----TSNDFGFAALDILTVYGED 1913 EG A ++ + +P P +V+WY G + G RY+ T D L I ++ D Sbjct: 2626 EGGQARFDVEMSAFPLP--KVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTD 2683 Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQSKESII 1943 SG Y C A N G V++I+ +++ KE I Sbjct: 2684 SGTYKCIATNEGG--VTTIKSDLKVKEPFI 2711 Score = 42.3 bits (95), Expect = 0.009 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 2/77 (2%) Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984 EG+ + L+ +V+ K P +EW +G+ ++ R K T D TL ++ D G Y Sbjct: 40 EGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCTLKIMPSERDDEGEY 97 Query: 2985 TCKAYNKRGEAFTSSTV 3001 C A N+ G+A ++ V Sbjct: 98 KCVATNEVGQATITTEV 114 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 5/116 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+ + EG ++ R+ G P +I+W K+ + I+ + R T+ + L Sbjct: 219 PEVFGDTAPINITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVL 276 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV---TPRATIERTSQHPETLQYIQQ 749 + +DSG Y C A S G A + ++V P+ + ++ ETL+ +++ Sbjct: 277 VLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEK 332 Score = 42.3 bits (95), Expect = 0.009 Identities = 35/148 (23%), Positives = 66/148 (44%), Gaps = 9/148 (6%) Query: 1663 TSGIAIVHSKKSIYLESQH-EGALPRLNQLEDTSKYQRHSAQDEVI----TQAPVFTMPM 1717 T I I K S+ LE +H E L ++ ++ +++ E++ T+ P F Sbjct: 361 TQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTP 420 Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF--GYVALNMKYV 1775 +++ V E +AR+ G P+ V+W + + R + D +L + Sbjct: 421 QNVTVLEGDEIRLDARV--GGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNA 478 Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 P DSG Y C+A N+ G+A + + ++ Sbjct: 479 KPLDSGVYICQATNDTGKATAEAEIQIE 506 Score = 42.3 bits (95), Expect = 0.009 Identities = 52/227 (22%), Positives = 83/227 (36%), Gaps = 19/227 (8%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 I++EE ++P F E + E E V P + + + K L R Sbjct: 503 IQIEELLVAP-EFAEEEATQLTLIEDDDMTLELHV--TGKPKPEVHWTKDNKPLTEDDRI 559 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 I +DI P D+G Y +A N G T + V ++ + + + Sbjct: 560 IIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNV----EVLFVAGISQVIG 615 Query: 2352 KIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVE 2411 IR + A K+P + P T+ LQ ++ + EG C+ G P E Sbjct: 616 SIRFIVLA---KKP------AGEAPEITESLQEMEEL-EGNPVTLTCKF--TGTPAPVAE 663 Query: 2412 WFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 WF+ + D R T ++TI R +D Y N +G Sbjct: 664 WFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG 710 Score = 42.3 bits (95), Expect = 0.009 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 9/126 (7%) Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749 +K N P+ I+D I+ EGG FD V G+P +++W H G + + Sbjct: 2023 KKGNRPQPIGMIRD-IEGYEGGQARFD--VHFTGNP--KVEWLHGEEQIIHGEKYKISEN 2077 Query: 3750 FG--FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR--DIVLESQLPQGMSG 3805 G +L + + D G YTC A+N+ G AT A + K + +E + ++ Sbjct: 2078 PGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDKHIAPMFVEDDTGEPITV 2137 Query: 3806 EKIKEL 3811 E KEL Sbjct: 2138 EAGKEL 2143 Score = 42.3 bits (95), Expect = 0.009 Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 38/216 (17%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P F L E +E +++ L+ ++ G VE++ + I R + + D +L Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIG--GFPRPTVEFYKDYDLIVDSERHKILEDGDRCSL 2377 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRY 1430 + ++ PED+G Y C TN LG + +RV Q E R+ Sbjct: 2378 IITNLRPEDAGTYKCVITNLLGVETSEAVIRV-------------------QEREHAPRF 2418 Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490 TD + +SVT + F K+ +I G K P V W K+G ++ Sbjct: 2419 DGTD-LGQSVTAQEGFELN-KTF--IIRG-------KPRPT------VTWMKDGNVISSS 2461 Query: 1491 HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 + +L II + EDSG YTC+AV+ +G Sbjct: 2462 NGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLG 2497 Score = 42.3 bits (95), Expect = 0.009 Identities = 30/136 (22%), Positives = 57/136 (41%), Gaps = 8/136 (5%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP F+ L + EG F+ + V KIEW K+G++ F I+ Sbjct: 2516 PPSFLSELPPLQVREG--FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNIT 2573 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755 L + ++D+G Y C + G + + A + +T + ++ PE + ++ +E Sbjct: 2574 LAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK------TRKPEAIAPLKSIESVEG 2627 Query: 756 YQHQESIEEQTSQRPQ 771 Q + +E P+ Sbjct: 2628 GQARFDVEMSAFPLPK 2643 Score = 42.3 bits (95), Expect = 0.009 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 6/98 (6%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY----DMG 3885 P+ I +KS +E EG + VE P +++WY G + G RY+ + D Sbjct: 2613 PEAIAPLKS--IESVEGGQARFDVEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGDRP 2670 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 +L I + DSG Y C A N+ G K+ + K+ Sbjct: 2671 VYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVKE 2708 Score = 41.9 bits (94), Expect = 0.012 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 9/128 (7%) Query: 2233 EVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292 E K + P F +L+ T V EG+ + +V+ P +E+ +G+ +Q R Sbjct: 18 EASPDKGTIPEFTKKLQPVT-VREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIK 74 Query: 2293 ITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEK 2352 TFD +L I +D GEY A N +G T I+ V K ++ ++PE +K Sbjct: 75 TTFDGERCTLKIMPSERDDEGEYKCVATNEVGQAT--ITTEVLVKETL----RKPEFKQK 128 Query: 2353 IRELESAE 2360 ++ L+ E Sbjct: 129 MQPLQVLE 136 Score = 41.9 bits (94), Expect = 0.012 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P F ++ P ++ EG ++ RI+ P P +VEW+ N + + R+ ++ + Sbjct: 123 PEFKQKMQ-PLQVLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYS 179 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 L I D+ Y C A + G++ + L+V+ K S Sbjct: 180 LIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTS 217 Score = 41.9 bits (94), Expect = 0.012 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 3/97 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P F T+++ + ++ E A FE R P+ VEWF K+ R+R + Sbjct: 1185 PDFKTKLKPM-EVTEESVAKFEVRSTGFPQPE--VEWFLGSTKIEDSGRFRVVSEQDRHE 1241 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 L I +++G Y+C N+ G ++A+LK K+ Sbjct: 1242 LIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKD 1278 Score = 41.9 bits (94), Expect = 0.012 Identities = 24/107 (22%), Positives = 48/107 (44%), Gaps = 4/107 (3%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 KP + +K +++ G ++ G +++W+KD +P++ R+ ++ Sbjct: 1380 KPSLEAELKP-VTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDKRVLPTYDGETC 1436 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014 LT + D Y A N +G +TSA L +V +K + + P Sbjct: 1437 VLTFHKAVLEDEAEYKVVAKNELGSVSTSAEL-LVNEKGAAPKIEKP 1482 Score = 41.9 bits (94), Expect = 0.012 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 5/86 (5%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG-- 2564 KP+ + L+ ++ E +E ++ G+P R WY +L G+ ++ D G Sbjct: 1735 KPVIVKPLSN-LQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791 Query: 2565 FVTLDINSVVANDAGLYMCKAINRAG 2590 TL +N +D+G+Y C A+N AG Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAG 1817 Score = 41.9 bits (94), Expect = 0.012 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 3/111 (2%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+F+++++ V ++ EG +L P EW NG + +R + D Sbjct: 1932 PRFVSELRPV-EVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYST 1988 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392 L L E+ G Y C+A N G S++A L K N + R +EG Sbjct: 1989 LKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGNRPQPIGMIRDIEG 2039 Score = 41.9 bits (94), Expect = 0.012 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 3/96 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P F+ L++ L E + + ++ PT VE+YKD I S R + + S Sbjct: 2320 PTFVVGLKETEGL-ESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 L I +LR EDAG+Y N LG S A IRV R Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412 Score = 41.5 bits (93), Expect = 0.016 Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 6/140 (4%) Query: 3377 KENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSV-EEEKGKAPVFTVPLSNIENLREG 3435 K++++L+ + + L K+ +S V + + E + P F N+ L EG Sbjct: 370 KDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVL-EG 428 Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF--GFVILEISPTYPEDSGEY 3493 + +AR+ +P V+W+ + + RF D L I P DSG Y Sbjct: 429 DEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVY 486 Query: 3494 LCRAYNNYGEAVTTASMKVQ 3513 +C+A N+ G+A A ++++ Sbjct: 487 ICQATNDTGKATAEAEIQIE 506 Score = 41.5 bits (93), Expect = 0.016 Identities = 24/79 (30%), Positives = 38/79 (48%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 V+W+ +GKPL G R ++ D G+Y C+ATN G+AT + +QV+ Sbjct: 1313 VKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372 Query: 3651 GRQGIILEPQLPSHFKSGT 3669 + +P L + K T Sbjct: 1373 VPKPRGSKPSLEAELKPVT 1391 Score = 41.5 bits (93), Expect = 0.016 Identities = 54/224 (24%), Positives = 89/224 (39%), Gaps = 41/224 (18%) Query: 1051 GTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG-YV-ALDIASV 1108 G + +EG +AR + VEW +QI + + + G Y+ +L + + Sbjct: 2032 GMIRDIEGYEGG-QARFDVHFTGNPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDL 2090 Query: 1109 RAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQ 1168 + ED G YT VA N +G+A ++H L K +HI Sbjct: 2091 KHEDGGRYTCVASNESGDA-----------------TLHANLNVKDKHIA---------- 2123 Query: 1169 IEEISKSKPVFVQPLSNPP-PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227 P+FV+ + P V GK +++ + G+P V W+ +G + R Sbjct: 2124 --------PMFVEDDTGEPITVEAGKELNVIMNIR--GNPRPDVNWYKDGSFLQQTGRMG 2173 Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271 + L + A D G Y A N LG+A + +V+V E Sbjct: 2174 ISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVEE 2217 Score = 41.5 bits (93), Expect = 0.016 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 3/68 (4%) Query: 2806 KIEWFFNNKPLPSGTRYK-STHDFSYV-SLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 K+EW + + G +YK S + Y+ SL + ED G YTC A+N G AT +L Sbjct: 2056 KVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANL 2115 Query: 2864 RCTGDKNI 2871 DK+I Sbjct: 2116 N-VKDKHI 2122 Score = 41.5 bits (93), Expect = 0.016 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F+V LK +E + + +I G P +E+ K+ I S R + SL Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIG--GFPRPTVEFYKDYDLIVDSERHKILEDGDRCSL 2377 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 + +L +D+G Y C + GV ++AV+ V R Sbjct: 2378 IITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412 Score = 41.5 bits (93), Expect = 0.016 Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 6/99 (6%) Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL--TYDG 4163 K R P L +VE G+ ARF ++ P P+V W G I +G RYK+ + DG Sbjct: 2609 KTRKPEAIAPLKSIESVEGGQ-ARFDVEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDG 2667 Query: 4164 ---MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199 +Y I + D+G + I LKV Sbjct: 2668 DRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706 Score = 41.5 bits (93), Expect = 0.016 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 4/65 (6%) Query: 3590 RVEWFHNGKPLLTGSRVKTIN----DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSC 3645 +V+W+H G + G R K I D L I + D+G Y C ATN G T+ Sbjct: 2643 KVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKS 2702 Query: 3646 KLQVK 3650 L+VK Sbjct: 2703 DLKVK 2707 Score = 41.1 bits (92), Expect = 0.021 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 3/96 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+F ++Q + +++EG F+ R+ P KVEWF N K+ + R+ + + Sbjct: 123 PEFKQKMQPL-QVLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYS 179 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377 L I ++ Y+C+AT++ G+ + L K Sbjct: 180 LIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEK 215 Score = 41.1 bits (92), Expect = 0.021 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 5/112 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F PL+++ ME E + G+P EWLK Q ++ + R + L Sbjct: 318 PKFTKPLETLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVVL 375 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV---TPRATIERTSQHPETLQ 745 ++ + + D Y A + +GVA ++A L V T + ++T Q+ L+ Sbjct: 376 EVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLE 427 Score = 41.1 bits (92), Expect = 0.021 Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 7/131 (5%) Query: 1432 KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH 1491 + +++ T KP F P+++ V+EG + + ++ + V+WFK Q V Sbjct: 402 EAELLVNEATEKPFFKKTPQNV-TVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEG 458 Query: 1492 RFRPIHD--FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE 1549 RF + D +L I + DSG+Y C+A N G + + E Sbjct: 459 RFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEE 518 Query: 1550 AGLEQIQVLED 1560 A Q+ ++ED Sbjct: 519 A--TQLTLIED 527 Score = 41.1 bits (92), Expect = 0.021 Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 7/103 (6%) Query: 902 VPESTQKPEFK-TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--I 958 V E+T+KP FK TP +++ EG +AR+ + T V+W K + V R I Sbjct: 407 VNEATEKPFFKKTP--QNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLI 462 Query: 959 TTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 +L I + D+G Y C+A N G+AT A + I Sbjct: 463 VDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 505 Score = 41.1 bits (92), Expect = 0.021 Identities = 31/137 (22%), Positives = 57/137 (41%), Gaps = 3/137 (2%) Query: 729 TPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNA 788 T TI+ T T + D + + + RP F + L+ + E++EG+ A Sbjct: 685 TTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPV-EVEEGQEA 743 Query: 789 HFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAV 848 + ++ V PT VEW+ +T + R I +L I +D +Y A Sbjct: 744 RLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVAS 801 Query: 849 NKLGEAISTASIRVAAR 865 N++G+ ++V + Sbjct: 802 NQVGKVTCRGDLKVTEK 818 Score = 41.1 bits (92), Expect = 0.021 Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 16/126 (12%) Query: 3830 PKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 P+F+ Q V + E + ++ K PK ++WY++GK L G R + Sbjct: 1281 PEFVGDQAAPIVVRQGEDIDIGAQITAK--PKPNVKWYKDGKPLRDGPRTTIRARDDLYN 1338 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948 +L ED+G Y C A N G KAT + D+ ++ PRG K S +EA Sbjct: 1339 CKVLSAKPEDTGMYKCEATNAVG----KAT----RTFDVQVEVPKPRGSKPS-----LEA 1385 Query: 3949 TIKKYT 3954 +K T Sbjct: 1386 ELKPVT 1391 Score = 41.1 bits (92), Expect = 0.021 Identities = 35/148 (23%), Positives = 57/148 (38%), Gaps = 5/148 (3%) Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837 + L + G++ C + S P KI+W ++KPL R T+D L Sbjct: 1385 AELKPVTVTAGEDTKLVCKI--SGKPQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHK 1442 Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897 ED Y A N GS +TS L +K + P ++A ++A Sbjct: 1443 AVLEDEAEYKVVAKNELGSVSTSAEL-LVNEKGAAPKIEKPLQDVKVDAGKKATFNTQVS 1501 Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVE 2925 G P+ E+ K E I+ +++ Sbjct: 1502 G--TPTPEVEWFKGESIVEDKGRFMIID 1527 Score = 41.1 bits (92), Expect = 0.021 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 4/105 (3%) Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026 V++K + + S + E T+FE Q+A G+P +V W+ L+ + + Sbjct: 1729 VNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLE 1786 Query: 4027 DFGYVAMNF--GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069 D G DSG Y C A N G ++A ++ TG+P Sbjct: 1787 DSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRP 1831 Score = 41.1 bits (92), Expect = 0.021 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 4/83 (4%) Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379 +E + NV + R P D V W+ +G ++ R + +D L + P+D Sbjct: 2137 VEAGKELNVIMNIRGNPRPD----VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDD 2192 Query: 1380 SGVYTCQATNQLGEAVTSCALRV 1402 +G+Y C+A N+LG A + ++V Sbjct: 2193 AGIYRCEAKNKLGTASRTVMVKV 2215 Score = 41.1 bits (92), Expect = 0.021 Identities = 19/58 (32%), Positives = 30/58 (51%) Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995 + +P + WY +G L+Q R ++S + L + D+GIY C+A NK G A Sbjct: 2150 RGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTA 2207 Score = 41.1 bits (92), Expect = 0.021 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 2/102 (1%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 Q+ EG L +V K P I W+ + + +R + + L+L ++ D+ Sbjct: 2234 QIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDA 2291 Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023 G+Y C A N +G +S+ V KD + K TEGLE Sbjct: 2292 GLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLE 2333 Score = 41.1 bits (92), Expect = 0.021 Identities = 29/129 (22%), Positives = 55/129 (42%), Gaps = 8/129 (6%) Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242 LS PP+ + + + + ++EW +GR+ T G + +D + L +A Sbjct: 2520 LSELPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNA 2579 Query: 1243 TSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVR 1302 T D G Y N G + +SA + + ++ T+ +AI ++ +E Q R Sbjct: 2580 TLKDAGRYQCIVTNKFGESSSSADISITQK------TRKPEAIAPLKSIESV--EGGQAR 2631 Query: 1303 EDITVMQAP 1311 D+ + P Sbjct: 2632 FDVEMSAFP 2640 Score = 40.7 bits (91), Expect = 0.028 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 +P E+ + + E + G P P V WT+ PL E ++ + + GD Sbjct: 511 APEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIII---DHKGDS 567 Query: 130 SLL-IKQIGPGDEGEYTCTARNQYG 153 ++ I + P D G Y C A+N+ G Sbjct: 568 CIVDIMAVTPNDSGTYKCEAKNKAG 592 Score = 40.7 bits (91), Expect = 0.028 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 6/119 (5%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P FT ++K ++V EG D RV VG PT ++WF R + + Sbjct: 726 PDFTKKLKP-VEVEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYT 782 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813 L I D Y C A+N+ G T + + K + ++ + EKI LE+ Sbjct: 783 LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK---MFPPEITRPERTEKIVLLEK 838 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 KP +K VT G L ++ P +++W + +P++ R TYD Sbjct: 1380 KPSLEAELKPVTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDKRVLPTYDGETCV 1437 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 L A ED Y A N +G T++ + V+ K Sbjct: 1438 LTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473 Score = 40.7 bits (91), Expect = 0.028 Identities = 54/253 (21%), Positives = 95/253 (37%), Gaps = 34/253 (13%) Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748 +EK P+ ++D + V G F+ +V G PT ++WF R ++ Sbjct: 1471 NEKGAAPKIEKPLQD-VKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIID 1527 Query: 3749 DF--GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806 D G L I+ D+G Y C N G T AK+ A ++ ++ E Sbjct: 1528 DAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAV-EVAPKTDKKLDEKEE 1586 Query: 3807 KIKELERGRISDAPK------EEPIV----STPPKFITQIKSH--------TVEES---E 3845 I LE + + K + ++ TP K T K H T+ ++ + Sbjct: 1587 PITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDD 1646 Query: 3846 GVRFECRVEPKEDPKL-------RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAED 3898 + C K + ++EW ++ K + + + G +L + +V +D Sbjct: 1647 AGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQD 1706 Query: 3899 SGEYICRAVNDFG 3911 G Y C+ N G Sbjct: 1707 KGVYKCKVTNKLG 1719 Score = 40.7 bits (91), Expect = 0.028 Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 7/105 (6%) Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493 DI T KP + KSIE+V EG F+ ++ KV+W+ G +T G R+ Sbjct: 2603 DISITQKTRKPEAIAPLKSIESV-EGGQARFDVEMSAFPLP--KVDWYHGGTKITHGGRY 2659 Query: 1494 RPIH----DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 + I D L I L DSG Y C A N G + L Sbjct: 2660 KIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDL 2704 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 8/90 (8%) Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSRF----TET 1629 T+ P LK++E EG +A F+ + +S L KV+WYH + G R+ + Sbjct: 2610 TRKPEAIAPLKSIESVEGGQARFD---VEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTD 2666 Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 + L I S DSGTY C A N G Sbjct: 2667 GDRPVYTLIIESLKYTDSGTYKCIATNEGG 2696 Score = 40.3 bits (90), Expect = 0.037 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637 P T L+ V ++EG+R + R+ T VEW + + ++ R T + L Sbjct: 27 PEFTKKLQPVTVREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84 Query: 1638 DIMSCLPEDSGTYTCRAINALGEA-VTSGIAI 1668 IM +D G Y C A N +G+A +T+ + + Sbjct: 85 KIMPSERDDEGEYKCVATNEVGQATITTEVLV 116 Score = 40.3 bits (90), Expect = 0.037 Identities = 21/64 (32%), Positives = 30/64 (46%) Query: 799 DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858 +P V WYKDG + + R+ + L + +DAG Y A NKLG A T Sbjct: 2152 NPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTV 2211 Query: 859 SIRV 862 ++V Sbjct: 2212 MVKV 2215 Score = 40.3 bits (90), Expect = 0.037 Identities = 36/118 (30%), Positives = 50/118 (42%), Gaps = 10/118 (8%) Query: 1694 TSKYQRHSAQDEV-ITQA---PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRN 1749 T+K+ S+ ++ ITQ P P+K I E A F+ + PK V+W Sbjct: 2592 TNKFGESSSSADISITQKTRKPEAIAPLKSIESVEGGQARFDVEMSAFPLPK--VDWYHG 2649 Query: 1750 GVPIEASNRL----TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 G I R +T D L ++ + DSGTY C A NE G S L V+ Sbjct: 2650 GTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVK 2707 Score = 40.3 bits (90), Expect = 0.037 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 7/88 (7%) Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL----TSD 2965 KPE I P+ + + GQ VE P K++WY G + G R+K+ D Sbjct: 2612 KPEAIAPLKSIESVEGGQARF---DVEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGD 2668 Query: 2966 FGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 TL + + DSG Y C A N+ G Sbjct: 2669 RPVYTLIIESLKYTDSGTYKCIATNEGG 2696 Score = 39.9 bits (89), Expect = 0.049 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 6/107 (5%) Query: 1172 ISKSKPVFVQPLSNPP----PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227 + K+KP V P P + E + LEC + G+P EW + + R K Sbjct: 308 VEKAKPKGVAPKFTKPLETLEIMEKETARLECTVT--GEPAPTTEWLKGDQPLKETQRIK 365 Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274 D V L++ H D Y V A N G A + A + V E ++ Sbjct: 366 IERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATE 412 Score = 39.9 bits (89), Expect = 0.049 Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 7/125 (5%) Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDL 1073 G+ K D S + KP F LK ++ E A FE R PQ + Sbjct: 1158 GMYKCVAKNDFGEASTSATLHINPVVKPDFKTKLKPM-EVTEESVAKFEVRSTGFPQPE- 1215 Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133 VEW+ +I + R + + L I+ V+ +D+G Y N AG A A + Sbjct: 1216 ---VEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQAGTAYSRADL 1272 Query: 1134 TVETR 1138 V+ + Sbjct: 1273 KVKEK 1277 Score = 39.9 bits (89), Expect = 0.049 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 3/96 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P F T LK + E + +V P ++EWF + R + + Sbjct: 1185 PDFKTKLKPMEVTEESVAKF---EVRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHE 1241 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 L I+ ++ D+G Y C N G A S A +K++++ Sbjct: 1242 LIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK 1277 Score = 39.9 bits (89), Expect = 0.049 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 6/94 (6%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG-YI- 694 PQ I ++ + EGG+ F+ G+P K+EWL + I ++ G Y+ Sbjct: 2028 PQPIGMIRDIEGYEGGQARFDVHF--TGNP--KVEWLHGEEQIIHGEKYKISENPGEYLY 2083 Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 SL + L +D G YTC A + +G A A L+V Sbjct: 2084 SLVVGDLKHEDGGRYTCVASNESGDATLHANLNV 2117 Score = 39.9 bits (89), Expect = 0.049 Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 4/69 (5%) Query: 94 KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQY 152 ++ G P P ++W R P+ N+ Y G VS L +K++ D G Y CTA N Sbjct: 2246 RVSGKPKPTITWFRDNTPVHTDNRVVASYE---GSVSALELKEMKLSDAGLYKCTATNSQ 2302 Query: 153 GEAICSVYI 161 G S + Sbjct: 2303 GSTSSSAEV 2311 Score = 39.9 bits (89), Expect = 0.049 Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 2/93 (2%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 PP F + L + E +++ DS ++EW +G+ G + D + Sbjct: 2516 PPSFLSELPPLQVREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNIT 2573 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 L +DAG Y C TN+ GE++ S + + Sbjct: 2574 LAFKNATLKDAGRYQCIVTNKFGESSSSADISI 2606 Score = 39.9 bits (89), Expect = 0.049 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 8/116 (6%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F+S L + +EG V ++D KIEW + + G + + D ++L Sbjct: 2519 FLSELPPLQVREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNITLAF 2576 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAE 2891 + +D+G Y C TN G +++S D +I T+ P+ A L+++E E Sbjct: 2577 KNATLKDAGRYQCIVTNKFGESSSS------ADISITQKTRKPEAIAPLKSIESVE 2626 Score = 39.5 bits (88), Expect = 0.065 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 KP F Q + P V EG + + R++ G PT +VEWF N + RF+ + Sbjct: 122 KPEFKQKMQ-PLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDLY 178 Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273 +L I +D Y A + G + + V E++ Sbjct: 179 SLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKT 216 Score = 39.5 bits (88), Expect = 0.065 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 5/117 (4%) Query: 3950 IKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEW 4009 + K S V +E +L + + P F Q+ T L E + + + ++ G P V+W Sbjct: 391 VAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVL-EGDEIRLDARVG--GKPEPTVDW 447 Query: 4010 FFNGKPLLHKNRFTPIYDF--GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064 F + + + RF + D ++ G P DSG Y+C+ATN G +A I+ Sbjct: 448 FKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQ 504 Score = 39.5 bits (88), Expect = 0.065 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 5/108 (4%) Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485 D K + + ++P F + K +E V EGQ + ++ N VEWF Sbjct: 708 DIGSVKSETRVRITALVRPDFTKKLKPVE-VEEGQEARLDVRVVGTPTPN--VEWFCGTT 764 Query: 1486 PVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR 1533 +T R+ I + L I + +D Y C A N VG +V+CR Sbjct: 765 KLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVG--KVTCR 810 Score = 39.5 bits (88), Expect = 0.065 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 4/117 (3%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 +P F + L P V EG+ L+ R+ +G PT VEWF +T R++ + Sbjct: 725 RPDFTKKLK-PVEVEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSY 781 Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLE 1292 L I D Y A N +G ++V E+ T+ E+ E+I LLE Sbjct: 782 TLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKMFPPEITRPERT-EKIVLLE 837 Score = 39.5 bits (88), Expect = 0.065 Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799 PK V+W ++G P+ R T + PED+G Y C A N +G+A + Sbjct: 1309 PKPNVKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFD 1368 Query: 1800 LFVQ------SKASLQLE 1811 + V+ SK SL+ E Sbjct: 1369 VQVEVPKPRGSKPSLEAE 1386 Score = 39.5 bits (88), Expect = 0.065 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 7/101 (6%) Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162 ++ G RP + + +E EG +A F+ V +P ++W H ++I G +Y+ + Sbjct: 2022 KKKGNRPQPIGMIRDIEGY-EGGQARFD--VHFTGNPK--VEWLHGEEQIIHGEKYKISE 2076 Query: 2163 DFGYVALDILY--TYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + G ++ ED G Y C A+N+ G+A L V Sbjct: 2077 NPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNV 2117 Score = 39.5 bits (88), Expect = 0.065 Identities = 18/64 (28%), Positives = 32/64 (50%) Query: 2138 DPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197 +P ++W+ +G ++ R + + L + +D+G Y C+A NKLG A T Sbjct: 2152 NPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTV 2211 Query: 2198 TLKV 2201 +KV Sbjct: 2212 MVKV 2215 Score = 39.5 bits (88), Expect = 0.065 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 V WY + L+ R ++ + L + +P+D+G Y C A N LG A + + V Sbjct: 2157 VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVE 2216 Query: 1671 SKKSIYLESQHEGALPRLNQLEDTSKY 1697 K + S G P Q+++ KY Sbjct: 2217 ELKGRGVPSFITGLFP--VQIKEGDKY 2241 Score = 39.5 bits (88), Expect = 0.065 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 2/95 (2%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F + +K+ E+ + ++ G P+ VE+ ++ I S R + D +L Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKI--GGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSL 2377 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + + PED+GTY C N LG + + + VQ + Sbjct: 2378 IITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412 Score = 39.1 bits (87), Expect = 0.086 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 5/95 (5%) Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-- 1626 +V+E T + P + +NV + EG + R+ + T V+W+ ++ + RF Sbjct: 406 LVNEAT-EKPFFKKTPQNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLI 462 Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 + +L I + P DSG Y C+A N G+A Sbjct: 463 VDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKA 497 Score = 39.1 bits (87), Expect = 0.086 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 4/104 (3%) Query: 1036 EVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRI 1092 ++K+T+K P P + T KIV + V + V+W+ +GK I ++R+ Sbjct: 812 DLKVTEKMFPPEITRPER-TEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRL 870 Query: 1093 QTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 L+I + ED+G YT A+N G + + + +E Sbjct: 871 NIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIE 914 Score = 39.1 bits (87), Expect = 0.086 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 ++KG P + +IE EG A F+ T N KVEW + + G +++ Sbjct: 2022 KKKGNRPQPIGMIRDIEGY-EGGQARFDVHFTG----NPKVEWLHGEEQIIHGEKYKISE 2076 Query: 3474 DFGFVI--LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 + G + L + ED G Y C A N G+A A++ V+ K Sbjct: 2077 NPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120 Score = 39.1 bits (87), Expect = 0.086 Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 6/128 (4%) Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028 K++PP F++++ L E +F+ V + K+EW +G+ +D Sbjct: 2513 KEEPPSFLSELPP---LQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDG 2569 Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIR 4088 + + F +D+G Y C TN +G + A I T K + +KSIE + Sbjct: 2570 RNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK---TRKPEAIAPLKSIESVE 2626 Query: 4089 EMEASWQV 4096 +A + V Sbjct: 2627 GGQARFDV 2634 Score = 39.1 bits (87), Expect = 0.086 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRI--- 958 + + T+KPE P+K S+ EGG A F+ + +V+W G + R Sbjct: 2606 ITQKTRKPEAIAPLKSIESV-EGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYKII 2662 Query: 959 -TTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 +T + L I+S+ D+G Y C A N G T ++L + Sbjct: 2663 QSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706 Score = 38.7 bits (86), Expect = 0.11 Identities = 25/110 (22%), Positives = 45/110 (40%), Gaps = 2/110 (1%) Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912 P ++EG R+ P P ++W + K ++ R T+ L + E Sbjct: 227 PINITEGDELDLSVRVRGKPKPE--IKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPE 284 Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962 DSG Y C A + G A +NV+ + + LE ++ +E ++ Sbjct: 285 DSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKET 334 Score = 38.7 bits (86), Expect = 0.11 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 3/96 (3%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP FT L++ + ++E + LE V P EW K L R+K D V Sbjct: 317 APKFTKPLETLE-IMEKETARLECTVTGEPAPTT--EWLKGDQPLKETQRIKIERDKDSV 373 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 L + + DD +Y A N G A S A + + + Sbjct: 374 VLEVRHVELDDEALYKVVAKNESGVATSEAELLVNE 409 Score = 38.7 bits (86), Expect = 0.11 Identities = 53/233 (22%), Positives = 86/233 (36%), Gaps = 23/233 (9%) Query: 3558 PEFTTTPS-DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 PEF + L L E+ E + V W + KPL R+ + I Sbjct: 512 PEFAEEEATQLTLIEDDDMTLELHV--TGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCI 569 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676 ++I V D+G Y C+A N+ G T + + V+ +L F +G I ++ Sbjct: 570 VDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVE-----VL-------FVAG---ISQVI 614 Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736 ++ R + + P T +++ ++ EG PV C+ G P +WF Sbjct: 615 GSI--RFIVLAKKPAGEAPEITESLQE-MEELEGNPVTLTCKF--TGTPAPVAEWFKAST 669 Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789 P G R L I D EY N GS + ++ +A Sbjct: 670 PVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITA 722 Score = 38.7 bits (86), Expect = 0.11 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 2/84 (2%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P F+ K + AKFE + G P P V W + + ++ + +EQ L Sbjct: 1185 PDFKTKLKPMEVTEESVAKFEVRSTGFPQPEVEWFLGSTKIEDSGRFRV-VSEQDRH-EL 1242 Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155 +I + D G Y CT NQ G A Sbjct: 1243 IISDVKVKDAGTYKCTLANQAGTA 1266 Score = 38.7 bits (86), Expect = 0.11 Identities = 32/129 (24%), Positives = 50/129 (38%), Gaps = 7/129 (5%) Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAV----NQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870 ++ + K + + R DV+V V P +L P ++ G+ C+I Sbjct: 1348 DTGMYKCEATNAVGKATRTFDVQVEVPKPRGSKPSLEAELK-PVTVTAGEDTKLVCKISG 1406 Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930 P P +++W + K L+ R + D L ED EY A N LG + Sbjct: 1407 KPQP--KIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVST 1464 Query: 1931 SIRLNVQSK 1939 S L V K Sbjct: 1465 SAELLVNEK 1473 Score = 38.7 bits (86), Expect = 0.11 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 3/94 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P F+T ++ + EG C++ + WF++ PV +R ++ A Sbjct: 2224 PSFITGLFPVQ-IKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSA 2280 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537 L++ ++ D+G+Y C A N G+ S +T + Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIK 2314 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F+ +K ES +R + ++ P+ +E+Y++ L+ R++ + D SL Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIGGF--PRPTVEFYKDYDLIVDSERHKILEDGDRCSL 2377 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 I + ED+G Y C N G + ++A I Sbjct: 2378 IITNLRPEDAGTYKCVITNLLGVETSEAVI 2407 Score = 38.3 bits (85), Expect = 0.15 Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 3/116 (2%) Query: 748 QQLEDYSKYQHQESIE-EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806 Q D K + I+ E+ P+F L E + E +T P V W Sbjct: 489 QATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLELHVT--GKPKPEVHW 546 Query: 807 YKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 KD +P+T RI ++IM + D+G+Y A NK G T + V Sbjct: 547 TKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNV 602 Score = 38.3 bits (85), Expect = 0.15 Identities = 24/97 (24%), Positives = 42/97 (43%), Gaps = 2/97 (2%) Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTI 1489 Y + D+ + P FV + V +G+ + ++ N+K W+K+G+P+ Sbjct: 1267 YSRADLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVK--WYKDGKPLRD 1324 Query: 1490 GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 G R ++ ED+G+Y C A N VG Sbjct: 1325 GPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVG 1361 Score = 38.3 bits (85), Expect = 0.15 Identities = 20/65 (30%), Positives = 29/65 (44%) Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508 +P V WY +G L+ R + L + P+D+G Y C A N G A T Sbjct: 2152 NPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTV 2211 Query: 3509 SMKVQ 3513 +KV+ Sbjct: 2212 MVKVE 2216 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 3/99 (3%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P F+T + + E + C+++ G P + WF + P+ NR Y+ A Sbjct: 2224 PSFITGL-FPVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSA 2280 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071 + + D+G Y C ATN G + A + K I Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319 Score = 38.3 bits (85), Expect = 0.15 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 6/70 (8%) Query: 2669 RTDPNLKIEWFKNG--VTLTTGARLKSTFD-FGLVTLSINSLRNDDSGIYTCKATNLLGE 2725 R P + W K+G ++ + G L+ + + LV + + +DSG YTC+A + LG+ Sbjct: 2442 RGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTK---EDSGNYTCQAVSSLGK 2498 Query: 2726 AVSTASIKIE 2735 A + +K+E Sbjct: 2499 ASQSFDLKVE 2508 Score = 38.3 bits (85), Expect = 0.15 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 5/109 (4%) Query: 3409 DTSVEEEKGKA--PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466 D VE K K P F L ++ +REG ++ T D K+EW +G++ G Sbjct: 2504 DLKVEAPKVKEEPPSFLSELPPLQ-VREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPG 2560 Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 D + L +D+G Y C N +GE+ ++A + + K Sbjct: 2561 GNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609 Score = 37.9 bits (84), Expect = 0.20 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 5/101 (4%) Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027 DK P F ++Q T + E E + ++ G P VEW +G+ + +R +D Sbjct: 22 DKGTIPEFTKKLQPVT-VREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFD 78 Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMD--ETKAVIKTT 4066 + +D GEY C ATN G T+ ++K T Sbjct: 79 GERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVKET 119 Score = 37.9 bits (84), Expect = 0.20 Identities = 23/95 (24%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 1567 TDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF 1626 T+++ + T + P ++ +++ EG F+ R+ T KVEW+ N + + RF Sbjct: 112 TEVLVKETLRKPEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRF 169 Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 + +L I D+ TY C A + G++ Sbjct: 170 EIIDEEDLYSLIIDDTRLSDADTYKCIATSEAGKS 204 Score = 37.9 bits (84), Expect = 0.20 Identities = 49/215 (22%), Positives = 79/215 (36%), Gaps = 37/215 (17%) Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764 I++ EG + RV G P I W + +P R+ T L + D Sbjct: 228 INITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPED 285 Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEP 3824 +G Y C A ++ G T S + D+ +E P+G++ + K LE I + Sbjct: 286 SGRYKCTAKSEHG--------TASKEFDVNVEKAKPKGVAPKFTKPLETLEIME------ 331 Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884 E R EC V +P EW + + L R + D Sbjct: 332 -------------------KETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDK 370 Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 V L++ +V +D Y A N+ G ++A + Sbjct: 371 DSVVLEVRHVELDDEALYKVVAKNESGVATSEAEL 405 Score = 37.9 bits (84), Expect = 0.20 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%) Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF- 1098 T+KP F + ++EG +ARV + + TV+W+ +++ R D Sbjct: 411 TEKPFFKKTPQNVT-VLEGDEIRLDARVGGKPE--PTVDWFKGDQKVAEEGRFLIVDDEE 467 Query: 1099 -GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 +L I + + DSGVY A N G+A A + +E Sbjct: 468 GDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIE 506 Score = 37.9 bits (84), Expect = 0.20 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 4/97 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P + PL ++ E FE +I G+P ++ W + + + + G + Sbjct: 1736 PVIVKPLSNLQVEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTF 1793 Query: 697 DMLSLNIQ--DSGEYTCRAVSATGVAETKAVLHVTPR 731 ++ + Q DSG Y C AV+ G A ++A L VT R Sbjct: 1794 TLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830 Score = 37.9 bits (84), Expect = 0.20 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 8/84 (9%) Query: 2380 QPLQNIDNIQ--EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG-YV-S 2435 QP+ I +I+ EG A FD G+P KVEW E+ I + + + G Y+ S Sbjct: 2029 QPIGMIRDIEGYEGGQARFDVHF--TGNP--KVEWLHGEEQIIHGEKYKISENPGEYLYS 2084 Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459 + + ++ ED G Y C ASN G+ Sbjct: 2085 LVVGDLKHEDGGRYTCVASNESGD 2108 Score = 37.9 bits (84), Expect = 0.20 Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 6/91 (6%) Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG-YV-ALNMKY 1774 ++DI E A F+ G+PK VEWL I + + G Y+ +L + Sbjct: 2034 IRDIEGYEGGQARFDVHF--TGNPK--VEWLHGEEQIIHGEKYKISENPGEYLYSLVVGD 2089 Query: 1775 VNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + ED G YTC A NE G+A + L V+ K Sbjct: 2090 LKHEDGGRYTCVASNESGDATLHANLNVKDK 2120 Score = 37.9 bits (84), Expect = 0.20 Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 9/106 (8%) Query: 1304 DITVMQA---PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360 DI++ Q P+ L +IE+VEG + + +V+W+ G I G R++ Sbjct: 2603 DISITQKTRKPEAIAPLKSIESVEGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYK 2660 Query: 1361 PAYEFD----YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 D L + S+ DSG Y C ATN+ G L+V Sbjct: 2661 IIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706 Score = 37.5 bits (83), Expect = 0.26 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729 P ++EWFK + R D G+ L I + +DSG+Y C N +GE + Sbjct: 1504 PTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTK 1563 Query: 2730 ASIKIE 2735 A ++++ Sbjct: 1564 AKLQVD 1569 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 5/87 (5%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 +PV +PL N+ ++E F+ ++ G+P +V W+ + + + D G Sbjct: 1735 KPVIVKPLSNLQ-VEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791 Query: 2435 SMT--ISHVRDEDEGVYMCRASNLLGE 2459 + T ++ + D GVY C A N G+ Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAGK 1818 Score = 37.5 bits (83), Expect = 0.26 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576 P E++EG ++ P+ FEW NG +++ +R + + D + TL + Sbjct: 1940 PVEVFEGNEVSLVCKLSAEAKPT--FEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIE 1997 Query: 2577 DAGLYMCKAINRAG 2590 D G Y C A N G Sbjct: 1998 DQGTYSCLAKNVFG 2011 Score = 37.5 bits (83), Expect = 0.26 Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 7/105 (6%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V + +P+ I+D I EGG A F+ +VEWL + + Sbjct: 2021 VKKKGNRPQPIGMIRD-IEGYEGGQARFDVHFT----GNPKVEWLHGEEQIIHGEKYKIS 2075 Query: 962 FNFG-YV-ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 N G Y+ +L + + D G YTC A N G AT ANL + K Sbjct: 2076 ENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120 Score = 37.5 bits (83), Expect = 0.26 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 7/101 (6%) Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823 ++ RPQ I ++D+ E EG A F+ T +P +VEW I + Sbjct: 2022 KKKGNRPQPIGMIRDI-EGYEGGQARFDVHFT--GNP--KVEWLHGEEQIIHGEKYKISE 2076 Query: 824 NFG-YV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 N G Y+ SL + L+ ED G YT A N+ G+A A++ V Sbjct: 2077 NPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNV 2117 Score = 37.1 bits (82), Expect = 0.35 Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 Q++EG + + +++ K P K+EW+ N ++ RF++ + +L + D D+ Sbjct: 133 QVLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDA 190 Query: 2982 GIYTCKAYNKRGEA 2995 Y C A ++ G++ Sbjct: 191 DTYKCIATSEAGKS 204 Score = 37.1 bits (82), Expect = 0.35 Identities = 18/59 (30%), Positives = 30/59 (50%) Query: 2532 VVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 V +G+P +W+ +G ++ SR TL+I++ DAG Y C+A N+ G Sbjct: 845 VTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG 903 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 5/104 (4%) Query: 1036 EVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRI 1092 ++K+ +K P F+G + +G+ A++ + V+WY +GK + R Sbjct: 1271 DLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPK--PNVKWYKDGKPLRDGPRT 1328 Query: 1093 QTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 + S + ED+G+Y A NA G+A + + VE Sbjct: 1329 TIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372 Score = 37.1 bits (82), Expect = 0.35 Identities = 20/65 (30%), Positives = 30/65 (46%) Query: 668 MKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLH 727 +K+EWLK+ + I F G +L + + QD G Y C+ + G A A L Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728 Query: 728 VTPRA 732 V +A Sbjct: 1729 VNEKA 1733 Score = 37.1 bits (82), Expect = 0.35 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%) Query: 2944 KIEWYFNGKVLEQGSRFKLTSDFGFVTLDLV--DVYERDSGIYTCKAYNKRGEA 2995 K+EW + + G ++K++ + G LV D+ D G YTC A N+ G+A Sbjct: 2056 KVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDA 2109 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 3/92 (3%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P FV ++ +T +E + + ++ G P VE++ + ++ R + D + Sbjct: 2320 PTFVVGLK-ETEGLESSDMRLDVKIG--GFPRPTVEFYKDYDLIVDSERHKILEDGDRCS 2376 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064 + + PED+G Y C TNL G++ ++AVI+ Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIR 2408 Score = 37.1 bits (82), Expect = 0.35 Identities = 22/83 (26%), Positives = 36/83 (43%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P+F +V EG + P+ + W ++G ++ S + SL Sbjct: 2416 PRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSL 2475 Query: 3890 DILYVYAEDSGEYICRAVNDFGE 3912 I+ V EDSG Y C+AV+ G+ Sbjct: 2476 VIIKVTKEDSGNYTCQAVSSLGK 2498 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 5/105 (4%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E + + +++P F + Q++ L EG +A++ +PT V+W+K + + R Sbjct: 404 ELLVNEATEKPFFKKTPQNVTVL-EGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRF 460 Query: 820 TSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 + + SL I + + D+G Y +A N G+A + A I++ Sbjct: 461 LIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 505 Score = 36.7 bits (81), Expect = 0.46 Identities = 18/55 (32%), Positives = 27/55 (49%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165 P FVS V V EG C+++ KP W NG+ + +R + ++DG Y Sbjct: 1932 PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRY 1986 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/61 (36%), Positives = 31/61 (50%) Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 TV W +G I+S+N + +L I V EDSG YT A ++ G+A S + V Sbjct: 2448 TVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKV 2507 Query: 1136 E 1136 E Sbjct: 2508 E 2508 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/119 (21%), Positives = 45/119 (37%), Gaps = 2/119 (1%) Query: 3794 VLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRV 3853 + E++L + + + G + + P F ++K VEE + R + RV Sbjct: 690 IKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEVEEGQEARLDVRV 749 Query: 3854 EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912 P +EW+ L RY + + +L I +D Y C A N G+ Sbjct: 750 VGTPTPN--VEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGK 806 Score = 36.3 bits (80), Expect = 0.61 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 10/81 (12%) Query: 2406 PTLKVEWFRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXX 2464 P V+W+++ K + D R T + D Y +S + ED G+Y C A+N +G+ Sbjct: 1309 PKPNVKWYKDGKPLRDGPRTTIRARDDLYNCKVLS-AKPEDTGMYKCEATNAVGK----- 1362 Query: 2465 XXXXXXXXXIQLETQHPEGMK 2485 +Q+E P G K Sbjct: 1363 ---ATRTFDVQVEVPKPRGSK 1380 Score = 36.3 bits (80), Expect = 0.61 Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 4/132 (3%) Query: 1942 IIRDSQ-HESALEK-IQYLEDDSRYKRAVQDDSFVVEKPQFGKP-IKNAEVTEGHPVHLE 1998 I+ DSQ H+S + K + E +A + + P F + +K+A G + Sbjct: 1796 IVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDEVKDAVYVRGGQ-EVS 1854 Query: 1999 ATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV 2058 LT PT V WY + + +Q+ K L I A D+G Y C A N Sbjct: 1855 LMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVAKNTH 1914 Query: 2059 GEAVTTSSVKVD 2070 G T V+V+ Sbjct: 1915 GSVSRTFDVRVE 1926 Score = 36.3 bits (80), Expect = 0.61 Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 2/102 (1%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 ++ EG + L ++ + P EW NG + +R + + D + TL ++ D Sbjct: 1942 EVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQ 1999 Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023 G Y+C A N G A + + + K N + + EG E Sbjct: 2000 GTYSCLAKNVFGSASSQAKLLVKKKGNRPQPIGMIRDIEGYE 2041 Score = 36.3 bits (80), Expect = 0.61 Identities = 14/55 (25%), Positives = 28/55 (50%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 G+P V W+++ ++ + R+ + + +T+ +D G+Y C A N LG Sbjct: 2151 GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLG 2205 Score = 36.3 bits (80), Expect = 0.61 Identities = 22/97 (22%), Positives = 43/97 (44%), Gaps = 2/97 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 + P F L ++ EG L ++ D ++EW +G+ G +++ + Sbjct: 2515 EPPSFLSELPPLQVREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNI 2572 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 L + +D+G Y C TN+ GE+ +S + + K Sbjct: 2573 TLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609 Score = 36.3 bits (80), Expect = 0.61 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 5/98 (5%) Query: 1464 FECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521 FE KL + VT + K+EW K+G+ T G D + L + +D+G Y C Sbjct: 2532 FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIV 2591 Query: 1522 VNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559 N G S + S T R + A L+ I+ +E Sbjct: 2592 TNKFGESSSSADI---SITQKTRKPEAIAPLKSIESVE 2626 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EGD + V P +K W ++KP+ R +T L ++ EDSG Y Sbjct: 232 EGDELDLSVRVRGKPKPEIK--WTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRY 289 Query: 2847 TCKATNSKGSAT 2858 C A + G+A+ Sbjct: 290 KCTAKSEHGTAS 301 Score = 35.9 bits (79), Expect = 0.80 Identities = 52/230 (22%), Positives = 84/230 (36%), Gaps = 24/230 (10%) Query: 3379 NLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVE-EEKGKAPVFTVPLSNIENLREGEN 3437 +LI+ + P ++ G+ Q D+ + ++ EE AP F + L E ++ Sbjct: 472 SLIIGNAKP--LDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDD 529 Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRA 3497 E +T P +V W + K L R I++I P DSG Y C A Sbjct: 530 MTLELHVTGKPKP--EVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEA 587 Query: 3498 YNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP 3557 N G V T + V +E G+ I I + + + +G Sbjct: 588 KNKAG--VNTRTFIVN------VEVLFVAGISQVIGSIRFI---------VLAKKPAGEA 630 Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK 3607 PE T + ++ E + C+ + EWF P+ G R K Sbjct: 631 PEITESLQEMEELEGNPVTLTCKF--TGTPAPVAEWFKASTPVRDGRRYK 678 Score = 35.9 bits (79), Expect = 0.80 Identities = 17/63 (26%), Positives = 29/63 (46%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P +++W KD +P+ R+ ++ L ED Y V A N+LG ++A Sbjct: 1408 PQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAE 1467 Query: 860 IRV 862 + V Sbjct: 1468 LLV 1470 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 3/85 (3%) Query: 4097 TPEQVVEESKARCPPVF--VSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154 T E V+ + P F L +VT +EG + G P+P V W+ +GN I + Sbjct: 2402 TSEAVIRVQEREHAPRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSS 2461 Query: 4155 SRYKLTYDG-MYHFDIPKTRQYDTG 4178 + L G Y I K + D+G Sbjct: 2462 NGVSLRQRGESYSLVIIKVTKEDSG 2486 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048 +TEG + L + P ++W + +P+++ R TT L + A ED+G Sbjct: 230 ITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSG 287 Query: 2049 TYMCKATNAVGEAVTTSSVKVD 2070 Y C A + G A V V+ Sbjct: 288 RYKCTAKSEHGTASKEFDVNVE 309 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/96 (23%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 P PKF T+ + +++E ++A E + +P EW + L R + D Sbjct: 313 PKGVAPKF-TKPLETLEIMEKETARLECTVT--GEPAPTTEWLKGDQPLKETQRIKIERD 369 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 V+L++ + ++ Y+ VA N+ G +++A L Sbjct: 370 KDSVVLEVRHVELDDEALYKVVAKNESGVATSEAEL 405 Score = 35.5 bits (78), Expect = 1.1 Identities = 31/109 (28%), Positives = 43/109 (39%), Gaps = 4/109 (3%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 KP F L P V+E E R G P VEWF + RF+ + Sbjct: 1184 KPDFKTKLK-PMEVTEESVAKFEVR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRH 1240 Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQA 1284 L I D G Y N G+A++ A ++V E+ D + +QA Sbjct: 1241 ELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK-DCAPEFVGDQA 1288 Score = 35.5 bits (78), Expect = 1.1 Identities = 17/55 (30%), Positives = 27/55 (49%) Query: 666 PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720 P ++W K+G+ + R T R + +LS +D+G Y C A +A G A Sbjct: 1309 PKPNVKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKA 1363 Score = 35.5 bits (78), Expect = 1.1 Identities = 17/59 (28%), Positives = 28/59 (47%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 V W KDG ++ + R+ + LT+ DAG Y C A N +G A+ + + + Sbjct: 2157 VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKV 2215 Score = 35.5 bits (78), Expect = 1.1 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 4/105 (3%) Query: 3412 VEEEKGKA-PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470 VEE KG+ P F L ++ ++EG+ R++ P + W+ + + +R Sbjct: 2215 VEELKGRGVPSFITGLFPVQ-IKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVV 2271 Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 + LE+ D+G Y C A N+ G ++A + ++ K Sbjct: 2272 ASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRK 2316 Score = 35.5 bits (78), Expect = 1.1 Identities = 31/153 (20%), Positives = 63/153 (41%), Gaps = 8/153 (5%) Query: 1787 AINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRF 1846 ++ + GE+ + + V + S Q S+L K Q + + + + P F Sbjct: 2465 SLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQ-----SFDLKVEAPKVKEEPPSF 2519 Query: 1847 ITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI 1906 +++L P ++ EG ++ + + ++EW +G+ G S D L Sbjct: 2520 LSELP-PLQVREG--FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAF 2576 Query: 1907 LTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 +D+G Y C N G++ SS +++ K Sbjct: 2577 KNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 6/73 (8%) Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR----TTHDFGFVTLDINSVVAND 2577 EG A ++ + P + +WY G ++ G R++ T D TL I S+ D Sbjct: 2626 EGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTD 2683 Query: 2578 AGLYMCKAINRAG 2590 +G Y C A N G Sbjct: 2684 SGTYKCIATNEGG 2696 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/71 (29%), Positives = 28/71 (39%), Gaps = 2/71 (2%) Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSLDITHTYEEDSGIYTCKATNS 2853 N + S PT ++EWF + R+ D L I EDSG+Y C N Sbjct: 1497 NTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFND 1556 Query: 2854 KGSATTSGSLR 2864 G T L+ Sbjct: 1557 IGETQTKAKLQ 1567 Score = 35.1 bits (77), Expect = 1.4 Identities = 17/64 (26%), Positives = 29/64 (45%) Query: 2274 LRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMT 2333 +++E+ + K + F G +L ++H V +D G Y K N LG T ++ Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728 Query: 2334 VTAK 2337 V K Sbjct: 1729 VNEK 1732 Score = 35.1 bits (77), Expect = 1.4 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 6/115 (5%) Query: 1027 SRYSKRTEEEVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNG 1083 S+ S + EV I +K P F+ LK T + +S+ V+ TVE+Y + Sbjct: 2301 SQGSTSSSAEVTIKRKDAIPTFVVGLKETEGL---ESSDMRLDVKIGGFPRPTVEFYKDY 2357 Query: 1084 KQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 I + R + D +L I ++R ED+G Y V N G A + V+ R Sbjct: 2358 DLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412 Score = 35.1 bits (77), Expect = 1.4 Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 38/221 (17%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P FV K E +E + + K+ VE++K+ + R + + D + Sbjct: 2320 PTFVVGLKETEG-LESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563 L I +L ED+G Y C NL L ++ ++R +Q E + Sbjct: 2377 LIITNLRPEDAGTYKCVITNL---------LGVETSEAVIR----------VQEREHAPR 2417 Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623 + TD+ VT Q L I G+ P V W + + S Sbjct: 2418 FDGTDLGQSVTAQEGF---ELNKTFIIRGKPR-------PT------VTWMKDGNVISSS 2461 Query: 1624 SRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664 + + +L I+ EDSG YTC+A+++LG+A S Sbjct: 2462 NGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQS 2502 Score = 34.7 bits (76), Expect = 1.9 Identities = 30/124 (24%), Positives = 50/124 (40%), Gaps = 10/124 (8%) Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499 + P+F T+P ++E + EC + EP + EW K QP+ R + D Sbjct: 316 VAPKF-TKPLETLEIMEKETARLECTVTGEPAPTT----EWLKGDQPLKETQRIKIERDK 370 Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD---IVRSTQNEAGLEQIQ 1556 V L++ + +D +Y A N G L T+ ++ QN LE + Sbjct: 371 DSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLEGDE 430 Query: 1557 VLED 1560 + D Sbjct: 431 IRLD 434 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 5/98 (5%) Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337 + E P F Q+VT L EG +AR+ +P V+WF +K+ R+ D Sbjct: 410 ATEKPFFKKTPQNVTVL-EGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDE 466 Query: 3338 GIVILDILYCYEE--NSGEYECVATNKLGRDSTKANLK 3373 + ++ + +SG Y C ATN G+ + +A ++ Sbjct: 467 EGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQ 504 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 2/82 (2%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA--TVSCKLQ 3648 V W+ + K L VK I L I D+G+Y C A N HG T +++ Sbjct: 1867 VMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVE 1926 Query: 3649 VKGRQGIILEPQLPSHFKSGTE 3670 V G+ + P G E Sbjct: 1927 VDGKAPRFVSELRPVEVFEGNE 1948 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 4/110 (3%) Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735 + TLH + ++D+ P + + I V G ++ + G+P ++W+ +G Sbjct: 2108 DATLHAN--LNVKDKHIAPMFVEDDTGEPITVEAGKELNVIMNIR--GNPRPDVNWYKDG 2163 Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 R+ + + L + DAG Y C A NK G+A+ T + Sbjct: 2164 SFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMV 2213 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/65 (30%), Positives = 30/65 (46%) Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264 G P V W +G ++ + +L II T D+G YT +AV+ LG A S Sbjct: 2443 GKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQS 2502 Query: 1265 AIVRV 1269 ++V Sbjct: 2503 FDLKV 2507 Score = 34.7 bits (76), Expect = 1.9 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 7/106 (6%) Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022 D+ K + P + ++S S VE +F+ +++ P KV+W+ G + H R+ Sbjct: 2603 DISITQKTRKPEAIAPLKSIES-VEGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRY 2659 Query: 4023 TPIY----DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064 I D + + DSG Y C ATN G+ K+ +K Sbjct: 2660 KIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLK 2705 Score = 34.7 bits (76), Expect = 1.9 Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 7/100 (7%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK----TYYD 1231 KP + PL + V EG + + P +V+W+H G +T G R+K T D Sbjct: 2612 KPEAIAPLKSIESV-EGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYKIIQSTDGD 2668 Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271 L I D+G Y A N G + ++V E Sbjct: 2669 RPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVKE 2708 Score = 34.3 bits (75), Expect = 2.5 Identities = 33/133 (24%), Positives = 54/133 (40%), Gaps = 5/133 (3%) Query: 2606 IIDQAMRPES--WEQIQLKEAAMNKVPEMFVDTGVQQAPIFTT-HLKSYDKLVEGQHVYL 2662 I++ + R +S ++ + + EA TG AP F +K + GQ V L Sbjct: 1796 IVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDEVKDAVYVRGGQEVSL 1855 Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNL 2722 + P+ + W+K+ L +K + L I +DSGIY C A N Sbjct: 1856 MLTINGFPTPD--VMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVAKNT 1913 Query: 2723 LGEAVSTASIKIE 2735 G T +++E Sbjct: 1914 HGSVSRTFDVRVE 1926 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 4124 EGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY---DGMYHFDIPKTRQYDTGKI 4180 EG ARF TG+PK V WL I++G +YK++ + +Y + + D G+ Sbjct: 2041 EGGQARFDVHFTGNPK--VEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRY 2098 Query: 4181 EVIXXXXXXXXXXXXXLKVIPRH 4203 + L V +H Sbjct: 2099 TCVASNESGDATLHANLNVKDKH 2121 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/98 (22%), Positives = 48/98 (48%), Gaps = 3/98 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P F+ +++ T+ +E + ++ P VE++ + + R++ D Sbjct: 2320 PTFVVGLKE-TEGLESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379 L I E++G Y+CV TN LG ++++A ++ +E+ Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREH 2414 Score = 34.3 bits (75), Expect = 2.5 Identities = 19/62 (30%), Positives = 29/62 (46%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 P +E++ + + R+K D SL IT+ ED+G Y C TN G T+ Sbjct: 2347 PRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAV 2406 Query: 2863 LR 2864 +R Sbjct: 2407 IR 2408 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 2/88 (2%) Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841 ++ +EG ++ + PT + W + + S SL I +E Sbjct: 2426 SVTAQEGFELNKTFIIRGKPRPT--VTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKE 2483 Query: 2842 DSGIYTCKATNSKGSATTSGSLRCTGDK 2869 DSG YTC+A +S G A+ S L+ K Sbjct: 2484 DSGNYTCQAVSSLGKASQSFDLKVEAPK 2511 Score = 34.3 bits (75), Expect = 2.5 Identities = 26/127 (20%), Positives = 56/127 (44%), Gaps = 6/127 (4%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRT-DMVDE---VTTQAPICTTSLKNVEIKEGQRAHF 1597 I++ T+ ++G Q + K ++ D+ E V + P + L ++++EG Sbjct: 2477 IIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGFEFKL 2536 Query: 1598 ERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINA 1657 +++ D+ K+EW + + G + + + L + +D+G Y C N Sbjct: 2537 IFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNK 2594 Query: 1658 LGEAVTS 1664 GE+ +S Sbjct: 2595 FGESSSS 2601 Score = 33.9 bits (74), Expect = 3.2 Identities = 17/63 (26%), Positives = 29/63 (46%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P ++W KD +PI + R+T+ L + + ED+G Y A ++ G A Sbjct: 246 PKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFD 305 Query: 860 IRV 862 + V Sbjct: 306 VNV 308 Score = 33.9 bits (74), Expect = 3.2 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576 P ++ EG RV G P W+ + + +R +++ L++ + + Sbjct: 2232 PVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLS 2289 Query: 2577 DAGLYMCKAINRAG 2590 DAGLY C A N G Sbjct: 2290 DAGLYKCTATNSQG 2303 Score = 33.5 bits (73), Expect = 4.3 Identities = 15/51 (29%), Positives = 22/51 (43%) Query: 4005 MKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055 +KVEW + KP+ + G + V +D G Y C+ TN G Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLG 1719 Score = 33.1 bits (72), Expect = 5.7 Identities = 46/197 (23%), Positives = 75/197 (38%), Gaps = 13/197 (6%) Query: 1408 LILESQHPSGLEKIQYLEDTSRYKKTDIIDESV---TIKPRFVTRPKSIENVIEGQHVHF 1464 LI++ S + + + + K T I++ SV T P I N+ EG + Sbjct: 180 LIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPI-NITEGDELDL 238 Query: 1465 ECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNL 1524 ++ +K W K+ +P+ R L + D EDSG Y C A + Sbjct: 239 SVRVRGKPKPEIK--WTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSE 296 Query: 1525 VGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTS- 1583 GT + + + LE ++++E T ++ T P TT Sbjct: 297 HGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIME-----KETARLECTVTGEPAPTTEW 351 Query: 1584 LKNVE-IKEGQRAHFER 1599 LK + +KE QR ER Sbjct: 352 LKGDQPLKETQRIKIER 368 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 5/87 (5%) Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-- 2563 EKP F + + L EG +ARV G P +W+ ++ RF D Sbjct: 412 EKPFFKKTPQNVTVL-EGDEIRLDARVG--GKPEPTVDWFKGDQKVAEEGRFLIVDDEEG 468 Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590 +L I + D+G+Y+C+A N G Sbjct: 469 DLFSLIIGNAKPLDSGVYICQATNDTG 495 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/87 (22%), Positives = 35/87 (40%) Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 PP+ ++ + E V +P+ ++W+++GK + R + Sbjct: 821 PPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYT 880 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFT 3915 L+I ED+G Y C A N G T Sbjct: 881 LNIHTTEPEDAGSYTCEAQNKMGTSST 907 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 2/95 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P LK VT G +I G P KI+W+K+ + ++ R + L Sbjct: 1381 PSLEAELKPVTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDKRVLPTYDGETCVL 1438 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 ++D EY A + G T A L V + Sbjct: 1439 TFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473 Score = 33.1 bits (72), Expect = 5.7 Identities = 17/66 (25%), Positives = 30/66 (45%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P KI+W K+ L R+ T+D L+ + +D Y A N LG ++A Sbjct: 1408 PQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAE 1467 Query: 2732 IKIEDR 2737 + + ++ Sbjct: 1468 LLVNEK 1473 Score = 33.1 bits (72), Expect = 5.7 Identities = 35/145 (24%), Positives = 51/145 (35%), Gaps = 4/145 (2%) Query: 3640 EATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE-DEKPNPPRFT 3698 E T+ L+ G L SG + E + T+E +P P F Sbjct: 1778 EGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFV 1837 Query: 3699 V-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDI 3757 E+KD + V G V + G PT + W+ + + V + L I Sbjct: 1838 EDEVKDAVYVRGGQEVSLMLTIN--GFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLII 1895 Query: 3758 DYIYARDAGEYTCRATNKWGSATTT 3782 D+G Y C A N GS + T Sbjct: 1896 YKASLNDSGIYRCVAKNTHGSVSRT 1920 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/66 (30%), Positives = 29/66 (43%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 PT + W+ ++K L K + L I DSGIY C A N+ GS + + Sbjct: 1863 PTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFD 1922 Query: 2863 LRCTGD 2868 +R D Sbjct: 1923 VRVEVD 1928 Score = 33.1 bits (72), Expect = 5.7 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 E+TI+ K P F V +K+ + E + D ++ G P ++++ + R Sbjct: 2310 EVTIK-RKDAIPTFVVGLKETEGL-ESSDMRLDVKIG--GFPRPTVEFYKDYDLIVDSER 2365 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 L D +L I + DAG Y C TN G T+ A I Sbjct: 2366 HKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVI 2407 Score = 33.1 bits (72), Expect = 5.7 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 3/104 (2%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 + K P F V L E L E + + ++ P VE+Y + + R + Sbjct: 2314 KRKDAIPTFVVGLKETEGL-ESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILE 2370 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517 D L I+ PED+G Y C N G + A ++VQ + + Sbjct: 2371 DGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREH 2414 Score = 32.7 bits (71), Expect = 7.5 Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 2/94 (2%) Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636 AP T L+ +EI E + A E + + EW ++PLK R + V Sbjct: 317 APKFTKPLETLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVV 374 Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 L++ +D Y A N G A + +V+ Sbjct: 375 LEVRHVELDDEALYKVVAKNESGVATSEAELLVN 408 Score = 32.7 bits (71), Expect = 7.5 Identities = 16/65 (24%), Positives = 28/65 (43%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G+P + W K+G ++ + R R+ L + D+G Y C A + G A Sbjct: 2151 GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRT 2210 Query: 724 AVLHV 728 ++ V Sbjct: 2211 VMVKV 2215 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 3/97 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P FIT + V ++ EG R+ P + WF + + +R ++ + Sbjct: 2224 PSFITGLFPV-QIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSA 2280 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 L++ ++G Y+C ATN G S+ A + K+ Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKD 2317 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 3/92 (3%) Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502 KP K + V G+ CK+ K++W K+ +P+ R P +D Sbjct: 1380 KPSLEAELKPV-TVTAGEDTKLVCKISGKPQP--KIDWMKDDKPLKPDKRVLPTYDGETC 1436 Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 L + ED Y A N +G+ S L Sbjct: 1437 VLTFHKAVLEDEAEYKVVAKNELGSVSTSAEL 1468 Score = 32.3 bits (70), Expect = 9.9 Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E KP P+ + + ++E FE ++ G+ RV W + + Sbjct: 1729 VNEKAVKPVIVKPLSN-LQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKML 1785 Query: 962 FNFGYVALT--IKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 + G T + HD+G Y C A N G+A + A L + Sbjct: 1786 EDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEV 1827 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDII--DLIAEDSGIYTCRAVNLVGTDEVSC 1532 N KVEW + + G +++ + G ++ DL ED G YTC A N G + Sbjct: 2054 NPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHA 2113 Query: 1533 RLTCR 1537 L + Sbjct: 2114 NLNVK 2118 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/75 (24%), Positives = 30/75 (40%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 V WY +G + R+ + L + +D+G+Y A+N G A + + VE Sbjct: 2157 VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVE 2216 Query: 1137 TRSSIDTSSIHRGLY 1151 S GL+ Sbjct: 2217 ELKGRGVPSFITGLF 2231 >SB_8817| Best HMM Match : I-set (HMM E-Value=0) Length = 2526 Score = 182 bits (442), Expect = 8e-45 Identities = 125/422 (29%), Positives = 197/422 (46%), Gaps = 15/422 (3%) Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461 E P +P+ P I TK++ V E EF E + W ++ + I T Sbjct: 1886 EQPTEPAGPRI-TKELVDAEVEETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKT 1944 Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521 T S L I + V+D ++ N+ G SA ++VEE PP F + Sbjct: 1945 DETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAV-ESEAEPPRFVTPLK 2003 Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581 + + G V + + GT PI + W K+ K++ PD R+ ++ +T+ I +D Sbjct: 2004 DQELEEGSTVDMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDE 2063 Query: 4582 GKY-ECVAINSAGEARCDAECVVSLP-ATKDKPKPQTKAANAP-PEIIEPLKDKI-VAEG 4637 Y + VA N AGEA DAE +V + A + P + A P P II+PL D+I V EG Sbjct: 2064 AMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEG 2123 Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697 ++ C I G P V WYK D L++ + D++TL I A +DE +YKCV Sbjct: 2124 DSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVV 2183 Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756 N AG V V +L V ++ +LP + L+D EG +F ++ K +P ++W + Sbjct: 2184 TNIAGSVDVKTELIV---EEGISLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPVVEWFK 2240 Query: 4757 EGALIPETPDFQMIHEGNNA-----VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 L+ ++ F +I + ++ L+I ED ++ A AG+ + KL+V Sbjct: 2241 NDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVN 2300 Query: 4812 SK 4813 SK Sbjct: 2301 SK 2302 Score = 160 bits (389), Expect = 2e-38 Identities = 116/416 (27%), Positives = 179/416 (43%), Gaps = 22/416 (5%) Query: 4400 VVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI 4459 +VE P P F K ++ VFE + R E G P P I W + +K Sbjct: 1153 IVEKP--EGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITT 1210 Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519 +L I ++D + +A N G A A L+V E +V P F T Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLVNE-------ALVKPKFIET 1263 Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579 + + +G+ V K G+ DV W V R I E+ T TL+I + P Sbjct: 1264 THDTEIITGESVWFRVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPI 1323 Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP---PEIIE-PLKDKIVA 4635 D G Y+C+ N AGE + VS +K KP T P P + E PLK ++ Sbjct: 1324 DKGNYKCIISNDAGE-----DMTVSKLTVIEKKKPITDVGTPPEFSPHVGEGPLK---IS 1375 Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695 +G + KI G+P P +QW+K DK +KPS+ ++ D ++L I A P+D Y C Sbjct: 1376 DGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTC 1435 Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754 A N +G T + ++ P + PL+ + E + T P +QW Sbjct: 1436 KATNKSGTTTRNINVDISALMPEGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQW 1495 Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 +E + E +I E +++ L+I T +D G++ + G+ + A+LVV Sbjct: 1496 FKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVV 1551 Score = 160 bits (388), Expect = 3e-38 Identities = 106/394 (26%), Positives = 177/394 (44%), Gaps = 29/394 (7%) Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481 V E E + G I WY+++ P+ +SP F+ + L I + ++D A + Sbjct: 882 VVEGSSVTIECQSSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEY 941 Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541 G + L+VEE ++ P +++ + R D +V G+ Sbjct: 942 RCDIATDRGVVSMTTELIVEE-------AVLMPVIIQPLKSLEIKEENAARFDVRVRGSP 994 Query: 4542 PIDVYWLKNGKKVQPDIRNKILEE-----DGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596 V W K+G+++Q R I+++ Y+L+I + P+D+G+YECVA+N AG+A Sbjct: 995 QPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKAT 1054 Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656 A V TK +T P+ EG I + G P V+W Sbjct: 1055 STATLQV---LTKISELDKT-----------PVH---TVEGSDITMKVAVSGTPRTEVEW 1097 Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716 YK D+ + K + + T D+Y L I+ A P D G YKCV N +G T + + + Sbjct: 1098 YKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYKCVTKNDSGTFTQMFDITIVEKP 1157 Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776 + + PL+ + V+E QP + + +T +P I WL+ G ++ E + +G Sbjct: 1158 EGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITTVFDGETC 1217 Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 VL I + +D G + C A G+ T A+L+V Sbjct: 1218 VLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 151 bits (365), Expect = 2e-35 Identities = 113/425 (26%), Positives = 181/425 (42%), Gaps = 32/425 (7%) Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453 + T E +VE V P+ + ++ + E ARF+V G P PL++W+++ +++ Sbjct: 953 SMTTELIVEEAVLM---PVIIQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQD 1009 Query: 4454 SPDFQI---HTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508 F I K + L+I V ED+ + VA N G A +A L V K + Sbjct: 1010 LGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKISE-- 1067 Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568 L V+ G + + V+GT +V W K+ +K+ I Sbjct: 1068 ---------LDKTPVHTVEGSDITMKVAVSGTPRTEVEWYKDDRKLSNRKPYVIKTTVDD 1118 Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628 Y L I A P D+G Y+CV N +G + + +KP+ A PE I+P Sbjct: 1119 YELTITSASPSDAGTYKCVTKNDSGTFTQMFDITI-----VEKPE------GAAPEFIKP 1167 Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688 LK V E Q + C + G P P + W KG ++K + L I+ + + Sbjct: 1168 LKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITTVFDGETCVLNITVSCLD 1227 Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748 DEG+YKC+A N G+ A+L V + T D + G+ F+ + Sbjct: 1228 DEGEYKCLAMNDFGKAATVAELLVNEALVKPKFIETT--HDTEIITGESVWFRVKYEGSP 1285 Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 P + W E L+ +T F + E + + L+I + D G + C + AG+ T +KL Sbjct: 1286 TPDVDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKL 1345 Query: 4809 VVKSK 4813 V K Sbjct: 1346 TVIEK 1350 Score = 149 bits (360), Expect = 7e-35 Identities = 93/337 (27%), Positives = 158/337 (46%), Gaps = 17/337 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F + + E F V+++G P P + WY E+ + ++ F I+T S LII Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTLII 1317 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSG 4528 V D + + N G + L V EK++ PP F+ + + ++ G Sbjct: 1318 EDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTPPEFSPHVGEGPLKISDG 1377 Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588 + L+ K+TG ++ W K+ K V+P + ++ D ++L I+ A P D+ KY C A Sbjct: 1378 GDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKA 1437 Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648 N +G + +S P+ +A P+ +EPLK + E + + K G Sbjct: 1438 TNKSGTTTRNINVDISALM------PEGEA----PKYVEPLKSDEIVEDSSFTMNVKFTG 1487 Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708 P+P VQW+K +K ++ + R +D TL I++ P+DEG YK V N G+ A Sbjct: 1488 TPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEA 1547 Query: 4709 KLKVTQPDQADN---LPALTPL--RDIVVYEGQPAQF 4740 +L V +A++ +P +TP + + GQ +F Sbjct: 1548 ELVVMTVSEAEDEGIIPKVTPTPGKTEITIPGQKPKF 1584 Score = 148 bits (358), Expect = 1e-34 Identities = 104/389 (26%), Positives = 169/389 (43%), Gaps = 25/389 (6%) Query: 4419 PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDS 4478 P E +V G P ++WY+++ + N + I T L I D+ Sbjct: 1072 PVHTVEGSDITMKVAVSGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDA 1131 Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538 + V +N GT ++ + EK +G P F + + V Q VRL+ VT Sbjct: 1132 GTYKCVTKNDSGTFTQMFDITIVEKP-EGAA----PEFIKPLKVLEVFETQPVRLECSVT 1186 Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598 GT + WLK G V+ D R + + T L I + D G+Y+C+A+N G+A Sbjct: 1187 GTPEPQITWLKGGDVVKEDDRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATV 1246 Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 AE +V+ K P+ IE D + G+++ F K G P P V WY Sbjct: 1247 AELLVNEALVK-------------PKFIETTHDTEIITGESVWFRVKYEGSPTPDVDWYH 1293 Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ- 4717 D L+ + F ++ D TL I + P D+G+YKC+ N AG +KL V + + Sbjct: 1294 EDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKP 1353 Query: 4718 ---ADNLPALTP---LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771 P +P + + +G + +IT + KP IQW ++ + + ++ + Sbjct: 1354 ITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDY 1413 Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 + L I +DT +TC+AT +G Sbjct: 1414 RDDIHSLTIVGASPDDTAKYTCKATNKSG 1442 Score = 146 bits (353), Expect = 5e-34 Identities = 160/710 (22%), Positives = 289/710 (40%), Gaps = 68/710 (9%) Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTGK 4179 + +EG+ R +VTG P+P V W +G + +L + + Y I + D+G Sbjct: 187 STDEGD-VRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGS 245 Query: 4180 IEVIXXXXXXXXXXXXXLKV-----IPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKT 4234 + + P+ + R +LK RP + + + E ++ Sbjct: 246 YRCTLTSDVGKSTRTFSVDIESEGPAPKESEKRKLLKGEERPKFVSDSTVE--EFKITDE 303 Query: 4235 FEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESR 4294 E R ++ G KP PE EW + K K ++ ++ E + I R Sbjct: 304 GELRLTVKVTG--------KPF----PEVEWTKDDKDLKEDD---RVIISEQDDGIVVLR 348 Query: 4295 LRE-STHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSES 4353 +++ H + +V+S+ + + D T E E+R KK+ + D +E Sbjct: 349 IKDVGAHDSGVYKCQVSSDVGTSTKS------FDVTIE-GERRKAKKLIEV----DETE- 396 Query: 4354 TVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIF 4413 H+ K+ + KE V ++++ T+++ Q +E V+ +K + Sbjct: 397 -------HLEKRIKHVKEPVPEEQVMPTKVKPVETKVDKPRQIEE--VDAMLKEEPTFLE 447 Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473 + +++P V E + + G+P P ++W++++ P+ I L+I++ Sbjct: 448 SDEIKPFEVTEEGDIKMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEP 507 Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV--NVTSGQLV 4531 +D + N G + + ++ V++ R+ V P F V T V Sbjct: 508 TKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDV 567 Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591 RL KVTG +V W K+GK V ++ ++ Y L I EA P DSG Y C + Sbjct: 568 RLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSD 627 Query: 4592 AGEA-RCDAECVVSL-PATKDKPKPQTKAANAPPEII--EPLKD-KIVAEGQAIEFSCKI 4646 G++ R + + S PATK+ K + + P+ + L++ KI EG+ + + K+ Sbjct: 628 VGKSTRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGE-LRLTVKV 686 Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-YTLRISEAFPEDEGDYKCVAYNSAGR-- 4703 GKP P V+W K DK +K +S D LRI + D G YKC + G Sbjct: 687 TGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTST 746 Query: 4704 ----VTV------AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753 VT+ A KL A + T + + + + ++ K +P + Sbjct: 747 KSFDVTIEGERRKAKKLIEVDDTVAPHFVEDTSIAPFELTDSGDVRLSVRVAGKPEPNFK 806 Query: 4754 WLREGALIP-ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802 W ++ I + + + L++ + D GT+ C AT G V Sbjct: 807 WTKDDEDIDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGGTV 856 Score = 140 bits (340), Expect = 2e-32 Identities = 134/466 (28%), Positives = 197/466 (42%), Gaps = 69/466 (14%) Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 +E ++PP F ++ + E VE DG IKW+++N + PD + H Sbjct: 1986 LEAVESEAEPPRFVTPLKDQELEEGSTVDMLVETDGTSPIHIKWFKDNKELV--PD-ERH 2042 Query: 4461 TFS---TKSILIIRQVFVEDSAVF-AAVAENRGGTAKCSANLVVEEKR-------RQGRG 4509 TF+ K + I V +ED A++ VAEN G A A ++VE K + Sbjct: 2043 TFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTPVEEVVD 2102 Query: 4510 GIVPPSFTLTAQN--VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567 VP + N ++V G VRL+ ++G V W K+ ++ D R + Sbjct: 2103 AAVPAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGD 2162 Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627 +TL+I A D +Y+CV N AG E +V + + P I E Sbjct: 2163 QHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIV-------------EEGISLPVIKE 2209 Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-----YTLRI 4682 LKD EG + F ++ GKP P V+W+K D+L+ S F + D+ ++L I Sbjct: 2210 GLKDTEANEGDVVRFDIRVAGKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVI 2269 Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ------PDQAD-NLPALTPL-------- 4727 PED+ Y VA N AG+ + KL V P QAD P L PL Sbjct: 2270 EGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVP 2329 Query: 4728 ------------------RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769 ++I V EG+ A+F + +P+I W R LIP+ F Sbjct: 2330 EEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPSIDWYRGEELIPDEGRFVH 2389 Query: 4770 IHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 I + L+I NT DTG +TC A ++ A L VK K Sbjct: 2390 IDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435 Score = 136 bits (328), Expect = 5e-31 Identities = 119/509 (23%), Positives = 208/509 (40%), Gaps = 30/509 (5%) Query: 4331 EVTEQRVQKKVTQKPRIPDPS-----ESTVHGKEVHVAKQKQTQKEVVGDKEITRKITST 4385 EVTE+ K Q P PS + + H+ ++ + KE T+K T Sbjct: 455 EVTEEGDIKMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGT 514 Query: 4386 ETTEIEHKAQTQERVVEGPV--------KPSKPPIFTK--KMQPCRVFEHEQARFEVEFD 4435 T E+ ++A R + V K + P F + P + + R V+ Sbjct: 515 YTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVT 574 Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G+P P + W ++ P+ P+ ++ + IL IR+ +DS + + G + + Sbjct: 575 GKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRT 634 Query: 4496 ANLVVEEK--------RRQGRGGIVPPSFTL--TAQNVNVTSGQLVRLDTKVTGTKPIDV 4545 ++ +E K +++ R G P F T + +T +RL KVTG +V Sbjct: 635 FSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGKPFPEV 694 Query: 4546 YWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604 W K+ K ++ D R I E+D G L I + DSG Y+C + G + + + Sbjct: 695 EWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFDVTIE 754 Query: 4605 LPATKDKPKPQTKAANAPPEIIEP-LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663 K K + AP + + + + + + S ++ GKP P +W K D+ I Sbjct: 755 GERRKAKKLIEVDDTVAPHFVEDTSIAPFELTDSGDVRLSVRVAGKPEPNFKWTKDDEDI 814 Query: 4664 K-PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722 S + R D TL + P D+G YKC A N G VT ++ + D + Sbjct: 815 DFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQVNMEGIDTGPQIQ 874 Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782 + ++I V EG + Q + I W ++ + ++P F+ + L I + Sbjct: 875 EYS--KEIEVVEGSSVTIECQSSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHD 932 Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 +D + C T G V + +L+V+ Sbjct: 933 IVIDDEAEYRCDIATDRGVVSMTTELIVE 961 Score = 133 bits (321), Expect = 4e-30 Identities = 99/336 (29%), Positives = 154/336 (45%), Gaps = 20/336 (5%) Query: 250 VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309 V + TE+ G +S P I + ++++ EG +F ++++G P P V WFKN + L +S Sbjct: 2190 VDVKTELIVEEG-ISLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPVVEWFKNDELLDDS 2248 Query: 310 NKHEIITTHNHT-----TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364 K II + +L + D Y+++A N G + G L V S E Sbjct: 2249 GKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAP 2308 Query: 365 DQRS------QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418 Q + + +T EE S + AP F++ ++ +V EG+ RFD V G Sbjct: 2309 AQADAATPILEPLVETIPEVPEEEAA-SPETKAPVFIETMKNIEVMEGEEARFDVHVDGV 2367 Query: 419 PYPEVTWFINDRQIRDD--YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAF 476 P P + W+ + I D+ + H V E L+I N L D+G TC+A N E Sbjct: 2368 PEPSIDWYRGEELIPDEGRFVHIDAVKEE-IFTLVIENTKLGDTGKYTCIAANDVDEITC 2426 Query: 477 QCRLNVIEKEQVVAPKFVER--FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534 + L V KE +AP+F + ST +V G+ V L+ G PTP++ W KD P+ Sbjct: 2427 EAVLTVKPKE--IAPEFQKEPEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGT 2484 Query: 535 PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 L + +L I K D+ Y A++ AG Sbjct: 2485 RRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAG 2520 Score = 128 bits (309), Expect = 1e-28 Identities = 112/462 (24%), Positives = 189/462 (40%), Gaps = 39/462 (8%) Query: 4371 EVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKP-PIFTKKMQP-CRVFEHEQA 4428 +VV + +T E +E K + VE V + P PI K + V E + Sbjct: 2068 KVVAENVAGEAVTDAEVI-VEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSV 2126 Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488 R E G P + WY++++ ++ T + LII+ ++D A + V N Sbjct: 2127 RLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNI 2186 Query: 4489 GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548 G+ L+VEE GI P ++ G +VR D +V G V W Sbjct: 2187 AGSVDVKTELIVEE-------GISLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPVVEWF 2239 Query: 4549 KNGKKVQPDIRNKILEE-----DGTYTLLILEAYPQDSGKYECVAINSAGE--------- 4594 KN + + + I+++ ++L+I P+D Y VA+N AG+ Sbjct: 2240 KNDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLV 2299 Query: 4595 ---------ARCDAECVVSLPATKDKPK-PQTKAANAP---PEIIEPLKDKIVAEGQAIE 4641 A+ DA + P + P+ P+ +AA+ P IE +K+ V EG+ Sbjct: 2300 NSKPEQEAPAQADAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEAR 2359 Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPS-KYFQMSRTADE-YTLRISEAFPEDEGDYKCVAYN 4699 F + G P P++ WY+G++LI ++ + +E +TL I D G Y C+A N Sbjct: 2360 FDVHVDGVPEPSIDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAAN 2419 Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759 +T A L V + A V G +T K P ++W ++ Sbjct: 2420 DVDEITCEAVLTVKPKEIAPEFQKEPEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDK 2479 Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 + T ++ + + L I +D+G +T A + AG+ Sbjct: 2480 PVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAGR 2521 Score = 126 bits (305), Expect = 3e-28 Identities = 119/504 (23%), Positives = 207/504 (41%), Gaps = 52/504 (10%) Query: 252 ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311 I E++ PP+ ++ +L+EG+ V+ G + WFK+ + L+ + Sbjct: 1982 IVEELEAVESEAEPPRFVTPLKDQELEEGSTVDMLVETDGTSPIHIKWFKDNKELVPDER 2041 Query: 312 HEIITTHNHTTLRVRN-TQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370 H N T+ + T + ++ +Y ++AEN G VT + VE + V Sbjct: 2042 HTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTP----- 2096 Query: 371 ITDTQQRETEERIEISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFIND 429 EE ++ + A P +K D DV EG R +C ++G P +V W+ +D Sbjct: 2097 --------VEEVVDAAVPA--PIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDD 2146 Query: 430 RQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488 + +D +I+ + G+ H L+I + L D CV N +G + + +I +E + Sbjct: 2147 YLLEED--ERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG--SVDVKTELIVEEGI 2202 Query: 489 VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-----HTDG 543 P E EG+ V + R G P P + W K+ + + + I D Sbjct: 2203 SLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDK 2262 Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXX 603 +L I D A Y A N AG +++ +L L +P + Sbjct: 2263 ELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKL--------------LVNSKPEQ--E 2306 Query: 604 XXXXXXXXXXYLRHVERARPYIPPGEEDRVYP---PPQFIVPLKSVTAMEGGKIHFETRI 660 L + P +P EE+ P P FI +K++ MEG + F+ + Sbjct: 2307 APAQADAATPILEPLVETIPEVP--EEEAASPETKAPVFIETMKNIEVMEGEEARFDVHV 2364 Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSI--FRFGYISLDMLSLNIQDSGEYTCRAVSATG 718 + V +P+ I+W + + I RF I + +L + + + D+G+YTC A + Sbjct: 2365 DGVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVD 2422 Query: 719 VAETKAVLHVTPRATIERTSQHPE 742 +AVL V P+ + PE Sbjct: 2423 EITCEAVLTVKPKEIAPEFQKEPE 2446 Score = 126 bits (304), Expect = 4e-28 Identities = 130/506 (25%), Positives = 211/506 (41%), Gaps = 59/506 (11%) Query: 87 GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146 G+ + ++ G P P WT+ ++ + ++L++K P D+G Y C Sbjct: 789 GDVRLSVRVAGKPEPNFKWTKDDED-IDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKC 847 Query: 147 TARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHV---SETVEHKAYGTQGYTTEQSRQ 203 TA N+ G + + EG V S T+E ++ G + + Sbjct: 848 TATNKGGTVTRTFQVNMEGIDTGPQIQEYSKEIEVVEGSSVTIECQSSGAEDARITWYKD 907 Query: 204 TQ--------KVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESI-TKRYVGESDVQIST 254 + A+ NG D +D E +R I T R V V ++T Sbjct: 908 DVPLGDSPRFETAFDNGLCSLRIHDIVIDD-------EAEYRCDIATDRGV----VSMTT 956 Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314 E+ V P I Q ++ +++E A+F V++ G+P+P V WFK+G++L + + I Sbjct: 957 ELIVEEA-VLMPVIIQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLGRFMI 1015 Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374 + + D Y+L+ E+ ++ E V + T T Sbjct: 1016 ----------IDDVDDQDKELYSLVIED----VIPEDAGEYECVA---VNEAGKATSTAT 1058 Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-- 432 Q T+ ISE P V + D+T V+G P EV W+ +DR++ Sbjct: 1059 LQVLTK----ISELDKTP--VHTVEGSDIT------MKVAVSGTPRTEVEWYKDDRKLSN 1106 Query: 433 RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPK 492 R Y K V++ + L IT+ + SD+G CV +N SG + ++EK + AP+ Sbjct: 1107 RKPYVIKTTVDD---YELTITSASPSDAGTYKCVTKNDSGTFTQMFDITIVEKPEGAAPE 1163 Query: 493 FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552 F++ L V E +PV L GTP P+ITW K G + + + DG L+I Sbjct: 1164 FIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITTVFDGETCVLNITV 1223 Query: 553 AKASDAAWYQCTAQNVAGSTATRARL 578 + D Y+C A N G AT A L Sbjct: 1224 SCLDDEGEYKCLAMNDFGKAATVAEL 1249 Score = 126 bits (303), Expect = 6e-28 Identities = 106/451 (23%), Positives = 196/451 (43%), Gaps = 34/451 (7%) Query: 4381 KITSTETTEIEHKAQ-TQERVVEGPVKPSKPPIFTKK--MQPCRVFEHEQARFEVEFDGE 4437 K T T + +IE K T+E + P K + P F ++ ++ + + R V+ G+ Sbjct: 630 KSTRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGK 689 Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVFVEDSAVFAAVAENRGGTAKCSA 4496 P P ++W +++ +K I +++ I+ V DS V+ + GT+ S Sbjct: 690 PFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSF 749 Query: 4497 NLVVEEKRRQGRGGI-----VPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549 ++ +E +RR+ + I V P F + +T VRL +V G + W K Sbjct: 750 DVTIEGERRKAKKLIEVDDTVAPHFVEDTSIAPFELTDSGDVRLSVRVAGKPEPNFKWTK 809 Query: 4550 NGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608 + + + E D TL++ P D G Y+C A N G + Sbjct: 810 DDEDIDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQV------- 862 Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668 + + P+I E K+ V EG ++ C+ G + WYK D + S Sbjct: 863 ------NMEGIDTGPQIQEYSKEIEVVEGSSVTIECQSSGAEDARITWYKDDVPLGDSPR 916 Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPL 4727 F+ + +LRI + +DE +Y+C G V++ +L V ++A +P + PL Sbjct: 917 FETAFDNGLCSLRIHDIVIDDEAEYRCDIATDRGVVSMTTELIV---EEAVLMPVIIQPL 973 Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA-----VLLIGN 4782 + + + E A+F ++ +P ++W ++G + + F +I + ++ L+I + Sbjct: 974 KSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIED 1033 Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 ED G + C A AG+ ++A L V +K Sbjct: 1034 VIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 116 bits (278), Expect = 6e-25 Identities = 84/335 (25%), Positives = 143/335 (42%), Gaps = 10/335 (2%) Query: 4379 TRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438 +R+ +T + ++ + E V + +K + + +++P V E + V+ G+P Sbjct: 40 SRRCKTTASAKLACLQRIPEEV-DAMLKEEPTFLESDEIKPFEVTEEGDIKLTVQVTGKP 98 Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498 P ++W +++ P+ I L+I++ +D + N G + + ++ Sbjct: 99 QPSVEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDV 158 Query: 4499 VVEEKRRQGRGGIVPPSFTLTAQNV--NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556 V++ R+ V P F V T VRL KVTG +V W K+GK V Sbjct: 159 SVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDK 218 Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA--RCDAECVVSLPATKDKPKP 4614 ++ ++ Y L I EA P DSG Y C + G++ + PA K+ K Sbjct: 219 LPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESEGPAPKESEKR 278 Query: 4615 QTKAANAPPEIIEPL---KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671 + P+ + + KI EG+ + + K+ GKP P V+W K DK +K + Sbjct: 279 KLLKGEERPKFVSDSTVEEFKITDEGE-LRLTVKVTGKPFPEVEWTKDDKDLKEDDRVII 337 Query: 4672 SRTADE-YTLRISEAFPEDEGDYKCVAYNSAGRVT 4705 S D LRI + D G YKC + G T Sbjct: 338 SEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTST 372 Score = 116 bits (278), Expect = 6e-25 Identities = 121/551 (21%), Positives = 216/551 (39%), Gaps = 33/551 (5%) Query: 4281 LQELENEQVIKESRLRESTHQYAIPGDKVTSNTVA---KSMAQRYEDNLDQTEEVTEQRV 4337 + E E+E +I + + IPG K V K + + + L + ++ Sbjct: 1554 VSEAEDEGIIPKVTPTPGKTEITIPGQKPKFGPVEVDIKGLKDKERERLTSEASIAGRKP 1613 Query: 4338 QKKVTQKPRIP-DPSESTVHGKEVHVAKQKQTQKEV-VGDKEITRKITSTETTEIEHKAQ 4395 V P + + TV E K + V +GD+ + + ++ A+ Sbjct: 1614 FGAVDMSITAPGEDKKPTVTEAEFTPVAFKPVEISVPIGDEAPFISLKGAKKPDLPVLAK 1673 Query: 4396 TQERVVEGPVKPSKP-PIFTKKMQP-CRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453 E ++ P++ P K + V E + AR E G P + WY++++ ++ Sbjct: 1674 PLEVIMPVSFTPAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEE 1733 Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513 T + LII+ ++D A + V N G+ L+VEE GI Sbjct: 1734 DERVSYETDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEE-------GISL 1786 Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGK-----KVQPDIRNKILEEDGT 4568 P ++ G++VR D +V G KP WL + K+ I + + ++D Sbjct: 1787 PVIKEGLKDTEANEGEIVRFDIRVAG-KPEP--WLNGSRMTSLWKILFIIIDDVDDKDKE 1843 Query: 4569 YTLLILE-AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627 L++E P D Y VA+N AG+ + +V +PK + A P I + Sbjct: 1844 LFSLVIEGCAPDDDAVYSVVAMNEAGKDTSKGKLLV-----HSRPKQEQPTEPAGPRITK 1898 Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687 L D V E + + V + +V W K + + TL IS++ Sbjct: 1899 ELVDAEVEETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDV 1958 Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQ----PDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743 +DEG Y C N G + +A++ V + +A+ +TPL+D + EG + Sbjct: 1959 DDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPLKDQELEEGSTVDMLVE 2018 Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN-TYEEDTGTFTCRATTAAGQV 4802 I+W ++ + +GN + I T E++ + A AG+ Sbjct: 2019 TDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEA 2078 Query: 4803 ETSAKLVVKSK 4813 T A+++V+ K Sbjct: 2079 VTDAEVIVEVK 2089 Score = 115 bits (276), Expect = 1e-24 Identities = 87/300 (29%), Positives = 134/300 (44%), Gaps = 31/300 (10%) Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338 EG+D +V +SG PR V W+K+ ++L N + I TT + L + + SD+G Y Sbjct: 1077 EGSDITMKVAVSGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYK- 1135 Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398 C+ + +S T + + D IT ++ E AP+F+K Sbjct: 1136 -------CVTKN-----DSGTFTQMFD-----ITIVEKPE----------GAAPEFIKPL 1168 Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458 + +V E + R +C VTG P P++TW +++D + V + L IT L Sbjct: 1169 KVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKED-DRITTVFDGETCVLNITVSCLD 1227 Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518 D G C+A N G+ A L V E +V PKF+E + GE V + G+P Sbjct: 1228 DEGEYKCLAMNDFGKAATVAELLV--NEALVKPKFIETTHDTEIITGESVWFRVKYEGSP 1285 Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 TP + W + + I+T+ STL I K D Y+C N AG T ++L Sbjct: 1286 TPDVDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKL 1345 Score = 113 bits (271), Expect = 4e-24 Identities = 119/516 (23%), Positives = 211/516 (40%), Gaps = 53/516 (10%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM--RYNEQTGDV 129 P+ Q K+ + A+F+ ++RG+P P+V W + L + ++ + ++Q ++ Sbjct: 967 PVIIQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKEL 1026 Query: 130 -SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH 188 SL+I+ + P D GEY C V + G + +T H Sbjct: 1027 YSLVIEDVIPEDAGEYEC------------VAVNEAGKATSTATLQVLTKISELDKTPVH 1074 Query: 189 KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES 248 T E S T KVA +GT + + +K D R++S R K YV ++ Sbjct: 1075 --------TVEGSDITMKVA-VSGTPRTEVEWYKDD-------RKLSNR----KPYVIKT 1114 Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQ-FQVQLSGNPRPRVTWFKNGQRLI 307 V + + ++ SP +K G Q F + + P F +++ Sbjct: 1115 TVD---DYELTITSASPSDAGTYKCVTKNDSGTFTQMFDITIVEKPEGAAPEFIKPLKVL 1171 Query: 308 NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ- 366 + + + T Q + ++ E+ V G V + T S + D+ Sbjct: 1172 EVFETQPVRLECSVT-GTPEPQITWLKGGDVVKEDDRITTVFDGETCVLNITVSCLDDEG 1230 Query: 367 --RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424 + + D + T + ++E + P+F++ D ++ G+ F + G P P+V Sbjct: 1231 EYKCLAMNDFGKAATVAELLVNEALVKPKFIETTHDTEIITGESVWFRVKYEGSPTPDVD 1290 Query: 425 WFINDRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483 W+ D + D + L+N E L+I +V D G C+ N +GE +L VI Sbjct: 1291 WYHEDTLVSD--TGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVI 1348 Query: 484 EKEQVVA-----PKFVERFST--LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536 EK++ + P+F L + +G + L + G P P I W KD P+ P+ + Sbjct: 1349 EKKKPITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQK 1408 Query: 537 LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572 +R+ +L I A D A Y C A N +G+T Sbjct: 1409 IRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTT 1444 Score = 110 bits (264), Expect = 3e-23 Identities = 132/550 (24%), Positives = 224/550 (40%), Gaps = 58/550 (10%) Query: 46 RQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSW 105 + + T+V+ + + A EP+ ++I K + G+ K ++ G P P V W Sbjct: 420 KPVETKVDKPRQIEEVDAMLKEEPTFLESDEI-KPFEVTEEGDIKMTAQVTGKPQPSVEW 478 Query: 106 TRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165 + P+ ++ E+ G SL+IK+ DEG YT N+ G + + + Sbjct: 479 FKDDVPVSPDEHITI--TEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDD 536 Query: 166 XXXXXXXXXXXXXYRHVSETVEHKAY--GTQGYTTEQSRQTQ-KVAYT-NGTDHSSTDDF 221 + V ++ G T + + + + +V +T +G + Sbjct: 537 TRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKLPNV 596 Query: 222 KVDTFEYRLL---REVSFRESITKRYVGESDVQISTE---ID-RSLGPVSPPKIAQKPRN 274 ++D E R + RE S +S + R SDV ST +D S GP + +KPR Sbjct: 597 ELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESKGPATKESEKKKPRK 656 Query: 275 S---------------KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319 K+ + + + V+++G P P V W K+ + L N+ II+ + Sbjct: 657 GEERPKFVSDSTLEEFKITDEGELRLTVKVTGKPFPEVEWTKDDKDLKEDNR-VIISEQD 715 Query: 320 H--TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR 377 LR+++ DSG Y C VTS V + T+S+ + ++R Sbjct: 716 DGIVVLRIKDVGAHDSGVYK--------CKVTSD---VGTSTKSF------DVTIEGERR 758 Query: 378 ETEERIEISEKALAPQFVKVCQDR--DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435 + ++ IE+ + +AP FV+ ++T+ R RV G+P P W +D I Sbjct: 759 KAKKLIEVDD-TVAPHFVEDTSIAPFELTDSGDVRLSVRVAGKPEPNFKWTKDDEDIDFR 817 Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETA--FQCRLNVIEKEQVVAPKF 493 + L++ + + SD G C A NK G FQ + I+ P+ Sbjct: 818 SSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQVNMEGID----TGPQI 873 Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553 E + V EG V + ++ G RITW KD VP+ +P D G +L I Sbjct: 874 QEYSKEIEVVEGSSVTIECQSSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDI 933 Query: 554 KASDAAWYQC 563 D A Y+C Sbjct: 934 VIDDEAEYRC 943 Score = 108 bits (259), Expect = 1e-22 Identities = 79/315 (25%), Positives = 139/315 (44%), Gaps = 25/315 (7%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 PK + ++++ G F+V+ G+P P V W+ + ++ + I T + +TL + Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTLII 1317 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 + + D G+Y + N G +T L V ++ + ITD E + Sbjct: 1318 EDVKPIDKGNYKCIISNDAGEDMTVSKLTVI---------EKKKPITDVGT-PPEFSPHV 1367 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 E L K+ D+T + ++TG P PE+ WF +D+ ++ + KI V+ Sbjct: 1368 GEGPL-----KISDGGDLT------LEVKITGEPKPEIQWFKDDKPVKP--SQKIRVDYR 1414 Query: 446 GN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVR 503 + H+L I + D+ TC A NKSG T +++ + APK+VE + + Sbjct: 1415 DDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGEAPKYVEPLKSDEIV 1474 Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563 E +N + GTP P + W K+ P+ + + I + +STL I + D Y+ Sbjct: 1475 EDSSFTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKI 1534 Query: 564 TAQNVAGSTATRARL 578 N G + A L Sbjct: 1535 VLSNPFGKAVSEAEL 1549 Score = 101 bits (241), Expect = 2e-20 Identities = 77/305 (25%), Positives = 127/305 (41%), Gaps = 20/305 (6%) Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584 VT +++ +VTG V W K+ V PD I EEDGTY+L+I E +D G Y Sbjct: 456 VTEEGDIKMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTY 515 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644 N AG R + V K PK K P + EG + + Sbjct: 516 TVEVSNEAGLGRRTFDVSVD-DTRKTIPKDAVKPKFIEDGSFVPFQS--TDEGD-VRLTV 571 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR- 4703 K+ GKP P V W K K + ++ D Y L I EA P+D G Y+C + G+ Sbjct: 572 KVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKS 631 Query: 4704 -----VTVAAKLKVT------QPDQADNLPAL---TPLRDIVVYEGQPAQFKTQITSKIK 4749 V + +K T +P + + P + L + + + + ++T K Sbjct: 632 TRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGKPF 691 Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLL-IGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 P ++W ++ + E + + + V+L I + D+G + C+ T+ G S + Sbjct: 692 PEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFDV 751 Query: 4809 VVKSK 4813 ++ + Sbjct: 752 TIEGE 756 Score = 99.5 bits (237), Expect = 6e-20 Identities = 120/540 (22%), Positives = 200/540 (37%), Gaps = 55/540 (10%) Query: 66 PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125 P E +P I + + +G +A+ E + G P V W + L E + S Y Sbjct: 1685 PAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEEDERVS--YETD 1742 Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEA-ICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184 +L+I+ DE EY C N G + + I EG + E Sbjct: 1743 GDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISLPVIKEGLKDTEANEGE 1802 Query: 185 TVEH--KAYGTQGYTTEQSRQTQ--KVAYT--NGTDHSSTDDFKV-----DTFEYRLLRE 233 V + G SR T K+ + + D + F + + + Sbjct: 1803 IVRFDIRVAGKPEPWLNGSRMTSLWKILFIIIDDVDDKDKELFSLVIEGCAPDDDAVYSV 1862 Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293 V+ E+ G+ V + ++ P P +I ++ +++++E + Sbjct: 1863 VAMNEAGKDTSKGKLLVHSRPKQEQPTEPAGP-RITKELVDAEVEETTPVTLVAEFVSEG 1921 Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353 VTW K+ R++ N+ I T +TL + + D G YT N G TS + Sbjct: 1922 ETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEV 1981 Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413 V EE + +A P+FV +D+++ EG Sbjct: 1982 IV------------------------EELEAVESEAEPPRFVTPLKDQELEEGSTVDMLV 2017 Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV-TCVARNKSG 472 G + WF +++++ D H + H + I+ VTL D + VA N +G Sbjct: 2018 ETDGTSPIHIKWFKDNKELVPDERHTF-TKDGNKHTMTISPVTLEDEAMYYKVVAENVAG 2076 Query: 473 ETAFQCRLNVIEKEQ-------------VVAPKFVERFST-LNVREGEPVVLNARAVGTP 518 E + V KE V AP ++ + ++V EG+ V L G P Sbjct: 2077 EAVTDAEVIVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRLECVISGGP 2136 Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 ++ W KD + + + TDG TL I A+ D A Y+C N+AGS + L Sbjct: 2137 DAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL 2196 Score = 99.1 bits (236), Expect = 8e-20 Identities = 81/307 (26%), Positives = 131/307 (42%), Gaps = 27/307 (8%) Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAE 341 D + V+++G P P VTW K+G+ + E+ + L +R DSG Y Sbjct: 566 DVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLT 625 Query: 342 NPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDR 401 + G + + +ES + + ++ + R+ EER + + +F + Sbjct: 626 SDVGKSTRTFSVDIESKGPATKESEKKK------PRKGEERPKFVSDSTLEEF------K 673 Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461 EG++ R +VTG+P+PEV W +D+ +++D I + G L I +V DSG Sbjct: 674 ITDEGEL-RLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSG 732 Query: 462 VVTCVARNKSGET--AFQCRL--------NVIEKEQVVAPKFVE--RFSTLNVREGEPVV 509 V C + G + +F + +IE + VAP FVE + + + V Sbjct: 733 VYKCKVTSDVGTSTKSFDVTIEGERRKAKKLIEVDDTVAPHFVEDTSIAPFELTDSGDVR 792 Query: 510 LNARAVGTPTPRITWQKDGVPI-IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568 L+ R G P P W KD I + + TL + SD Y+CTA N Sbjct: 793 LSVRVAGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATN- 851 Query: 569 AGSTATR 575 G T TR Sbjct: 852 KGGTVTR 858 Score = 98.3 bits (234), Expect = 1e-19 Identities = 145/697 (20%), Positives = 276/697 (39%), Gaps = 102/697 (14%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFE--- 1598 I T+ + G ++V + RT V T+ I ++K I++G F+ Sbjct: 130 IKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTD 189 Query: 1599 ----RRLIPVSDATL-KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCR 1653 R + V+ +V W + KP+ + L I P+DSG+Y C Sbjct: 190 EGDVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCT 249 Query: 1654 AINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVF 1713 + +G+ S ++ ++ + EG P+ ++ K + + + ++ + V Sbjct: 250 LTSDVGK----------STRTFSVDIESEGPAPKESEKR---KLLKGEERPKFVSDSTV- 295 Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDFGYVALNM 1772 ++ ++ + ++ G P VEW ++ ++ +R + + D G V L + Sbjct: 296 ----EEFKITDEGELRLTVKV--TGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRI 349 Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFVQS---KASLQLESQHESALQK--------- 1820 K V DSG Y C+ +++G + S + ++ KA +E L+K Sbjct: 350 KDVGAHDSGVYKCQVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPV 409 Query: 1821 ---------IQQLEDSSRYQRR-EDVEVAVNQAPRFITQLN-GPTKLSEGQSAHYECRIE 1869 ++ +E R+ E+V+ + + P F+ P +++E ++ Sbjct: 410 PEEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQVT 469 Query: 1870 PYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929 P P+ VEW+ + + + + G +L I +D G YT + N G Sbjct: 470 GKPQPS--VEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGR 527 Query: 1930 SSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEV 1989 + ++V I D+ + ++D SFV P ++ + Sbjct: 528 RTFDVSVDDTRKTI---------------PKDAVKPKFIEDGSFV--------PFQSTD- 563 Query: 1990 TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGT 2049 EG + T+ P V W +G+PV + + + L I A +D+G+ Sbjct: 564 -EGD---VRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGS 619 Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRP 2109 Y C T+ VG++ T SV +++K +E EK ++P+ EE RP Sbjct: 620 YRCTLTSDVGKSTRTFSVDIESKG------------PATKESEK-KKPRKGEE-----RP 661 Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH-DFGYVA 2168 F++ T LE K D V+ P ++W + + ++ +R + D G V Sbjct: 662 KFVSDST-LEEFKITDEGELRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVV 720 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR 2205 L I A DSG Y CK T+ +G + + + + G R Sbjct: 721 LRIKDVGAHDSGVYKCKVTSDVGTSTKSFDVTIEGER 757 Score = 97.9 bits (233), Expect = 2e-19 Identities = 166/760 (21%), Positives = 294/760 (38%), Gaps = 121/760 (15%) Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSG 334 ++ E D + VQ++G P+P V W K+ ++ ++H IT + T +L ++ K D G Sbjct: 81 EVTEEGDIKLTVQVTGKPQPSVEWLKDDVP-VSPDEHITITEEDDTYSLVIKEPTKKDEG 139 Query: 335 HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQF 394 YT+ N G +R+ ++ R+T I + A+ P+F Sbjct: 140 TYTVEVSNEAGL------------------GRRTFDVSVDDTRKT-----IPKDAVKPKF 176 Query: 395 VK---VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 ++ + EG + R +VTG+P PEVTW + + + D + L ++ + L Sbjct: 177 IEDGSFVPFQSTDEGDV-RLTVKVTGKPEPEVTWTKDGKPV-DKLPNVELDHQEDRYILT 234 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNV---------IEKEQVV----APKFVERFS 498 I + DSG C + G++ +++ EK +++ PKFV + Sbjct: 235 IREASPDDSGSYRCTLTSDVGKSTRTFSVDIESEGPAPKESEKRKLLKGEERPKFVSDST 294 Query: 499 TLNVR---EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-HTDGGASTLDIPRAK 554 + EGE + L + G P P + W KD + + + I D G L I Sbjct: 295 VEEFKITDEGE-LRLTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVG 353 Query: 555 ASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRL-------HLPRPTK-VXXXXX 606 A D+ Y+C V+ T + + K+L HL + K V Sbjct: 354 AHDSGVYKC---QVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVP 410 Query: 607 XXXXXXXYLRHVERA--RPYIPPGEEDRVYPPPQFIV--PLKSVTAMEGGKIHFETRIEP 662 ++ VE +P + + P F+ +K E G I ++ Sbjct: 411 EEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQV-- 468 Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET 722 G P +EW K+ + T G SL + +D G YT + G+ Sbjct: 469 TGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLG-- 526 Query: 723 KAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGEL 782 R T + ++D K +++++ + + F+ P Q E Sbjct: 527 --------RRTFD------------VSVDDTRKTIPKDAVKPKFIEDGSFV-PFQSTDE- 564 Query: 783 QEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGS 842 + ++T +P V W KDG+P+ + L I +D+GS Sbjct: 565 ---GDVRLTVKVTGKPEP--EVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGS 619 Query: 843 YTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXV 902 Y + +G++ T S+ + ++ T + + R+ E+ V Sbjct: 620 YRCTLTSDVGKSTRTFSVDIESKGPATKESEKKKPRKGEERP---------------KFV 664 Query: 903 PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTF 961 +ST + EFK I D+ ++ G VEW KD + ++ +R I + Sbjct: 665 SDSTLE-EFK--ITDE--------GELRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISE 713 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 + G V L IK V HD+G Y C+ + +G +T S ++TI Sbjct: 714 QDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFDVTI 753 Score = 97.9 bits (233), Expect = 2e-19 Identities = 77/306 (25%), Positives = 128/306 (41%), Gaps = 22/306 (7%) Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584 VT ++L +VTG V WLK+ V PD I EED TY+L+I E +D G Y Sbjct: 82 VTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTY 141 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644 N AG R + V K PK K P + EG + + Sbjct: 142 TVEVSNEAGLGRRTFDVSVD-DTRKTIPKDAVKPKFIEDGSFVPFQS--TDEGD-VRLTV 197 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 K+ GKP P V W K K + ++ D Y L I EA P+D G Y+C + G+ Sbjct: 198 KVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKS 257 Query: 4705 T---------------VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749 T + K K+ + ++ + + + + + + + ++T K Sbjct: 258 TRTFSVDIESEGPAPKESEKRKLLKGEERPKFVSDSTVEEFKITDEGELRLTVKVTGKPF 317 Query: 4750 PTIQWLREGALIPETPDFQMIHEGNN--AVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807 P ++W ++ + E D +I E ++ VL I + D+G + C+ ++ G S Sbjct: 318 PEVEWTKDDKDLKE-DDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTSTKSFD 376 Query: 4808 LVVKSK 4813 + ++ + Sbjct: 377 VTIEGE 382 Score = 93.5 bits (222), Expect = 4e-18 Identities = 63/197 (31%), Positives = 92/197 (46%), Gaps = 19/197 (9%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT----Y 4569 P F T +N+ V G+ R D V G + W + G+++ PD + + D + Sbjct: 2341 PVFIETMKNIEVMEGEEARFDVHVDGVPEPSIDWYR-GEELIPD-EGRFVHIDAVKEEIF 2398 Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629 TL+I D+GKY C+A N E C+A V KPK AP EP Sbjct: 2399 TLVIENTKLGDTGKYTCIAANDVDEITCEAVLTV-------KPKEI-----APEFQKEPE 2446 Query: 4630 KDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688 K V G + + GKP P V+W+K DK +K ++ ++ DE++L+I P+ Sbjct: 2447 KSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPD 2506 Query: 4689 DEGDYKCVAYNSAGRVT 4705 D G Y VA + AGR T Sbjct: 2507 DSGKYTVVAESPAGRDT 2523 Score = 91.9 bits (218), Expect = 1e-17 Identities = 184/918 (20%), Positives = 349/918 (38%), Gaps = 156/918 (16%) Query: 1704 DEVITQAPVFTMPMKDIRVAE-NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762 D ++ + P F + +I+ E + + + G P+ VEWL++ VP+ +T Sbjct: 62 DAMLKEEPTF-LESDEIKPFEVTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHITIT 120 Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQ 1822 + +L +K +D GTY T+ V ++A L + S Sbjct: 121 EEDDTYSLVIKEPTKKDEGTY---------------TVEVSNEAGLGRRTFDVS------ 159 Query: 1823 QLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF 1882 ++D+ + ++ V+ + F+ P + ++ ++ P+P V W Sbjct: 160 -VDDTRKTIPKDAVKPKFIEDGSFV-----PFQSTDEGDVRLTVKVTGKPEPE--VTWTK 211 Query: 1883 NGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942 +GK + + L I +DSG Y C +++G++ + ++++S+ Sbjct: 212 DGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESEGPA 271 Query: 1943 IRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLT 2002 ++S EK + L+ + R K FV + ++ ++T+ + L +T Sbjct: 272 PKES------EKRKLLKGEERPK-------FVSDST-----VEEFKITDEGELRLTVKVT 313 Query: 2003 PVNDPTMRVEWYCNGRPVQQGHR-FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEA 2061 P VEW + + +++ R + D G V L I A D+G Y C+ ++ VG + Sbjct: 314 --GKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTS 371 Query: 2062 VTTSSVKVD-----AKSGLYLDTLD--EQRLKKIQE--------------LE-KYERPKP 2099 + V ++ AK + +D + E+R+K ++E +E K ++P+ Sbjct: 372 TKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVPEEQVMPTKVKPVETKVDKPRQ 431 Query: 2100 IEEEQP--GQRPVFLTA--LTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155 IEE + P FL + + E +EGD + + P +++WF + + Sbjct: 432 IEEVDAMLKEEPTFLESDEIKPFEVTEEGD---IKMTAQVTGKPQPSVEWFKDDVPVSPD 488 Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN 2215 T + G +L I +D GTY + +N EA Sbjct: 489 EHITITEEDGTYSLVIKEPTKKDEGTYTVEVSN---EA---------------------- 523 Query: 2216 GLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKT-AHFECQVEPVHDPNL 2274 GL + R + TR + + + P +F+ + G+ F+ V+ P Sbjct: 524 GLGR-RTFDVSVDDTRKTIPKDAVKP-KFIED--GSFVPFQSTDEGDVRLTVKVTGKPEP 579 Query: 2275 RIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 + + +GK + + L I+ P+D+G Y + +G T S+ + Sbjct: 580 EVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDI 639 Query: 2335 TAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTA 2394 +KG ES++ K+P E +RP F ++ + Sbjct: 640 ESKGPATKESEK----------------KKPRKGE----ERPKFVSD-STLEEFKITDEG 678 Query: 2395 HFDCRLIPVGDPTLKVEWFRNEK-LIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453 + G P +VEW +++K L ED+ I D G V + I V D GVY C+ Sbjct: 679 ELRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKV 738 Query: 2454 SNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQV 2513 ++ +G I+ E + + + ++ PH Sbjct: 739 TSDVG------TSTKSFDVTIEGERRKAKKLIEVDDTVAPH--------------FVEDT 778 Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM-GSRFRTTHDFGFVTLDINS 2572 P EL + RV G P F+W + ++ S++ +TL + S Sbjct: 779 SIAPFELTDSGDVRLSVRV--AGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIVKS 836 Query: 2573 VVANDAGLYMCKAINRAG 2590 +D G Y C A N+ G Sbjct: 837 PSPSDQGTYKCTATNKGG 854 Score = 91.5 bits (217), Expect = 2e-17 Identities = 66/247 (26%), Positives = 107/247 (43%), Gaps = 11/247 (4%) Query: 1566 RTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSR 1625 +T+++ E P+ LK+ E EG F+ R+ + VEW+ N++ L + Sbjct: 2193 KTELIVEEGISLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGK 2250 Query: 1626 F-----TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQ 1680 F + + +L I C PED Y+ A+N G+ + G +V+SK +Q Sbjct: 2251 FIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQ 2310 Query: 1681 HEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDP 1740 + A P L L +T T+APVF MK+I V E + A F+ + V +P Sbjct: 2311 ADAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEP 2370 Query: 1741 KLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPE--DSGTYTCRAINELGEAVTSS 1798 ++W R I R + + N + D+G YTC A N++ E + Sbjct: 2371 S--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEA 2428 Query: 1799 TLFVQSK 1805 L V+ K Sbjct: 2429 VLTVKPK 2435 Score = 87.8 bits (208), Expect = 2e-16 Identities = 80/332 (24%), Positives = 145/332 (43%), Gaps = 41/332 (12%) Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969 KP++I + +++ G+ + + E PD ++WY ++ RF + ++ Sbjct: 1257 KPKFI-ETTHDTEIITGESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRFLINTEEDTS 1313 Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLE 3029 TL + DV D G Y C N +A TV SK +IE+ Sbjct: 1314 TLIIEDVKPIDKGNYKCIISN---DAGEDMTV---SKLTVIEK----------------- 1350 Query: 3030 DSLRKEPGQQPDDDTGRPPEFTT-VFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG 3088 ++P D G PPEF+ V + + IS+G E + TG+ I+WF + Sbjct: 1351 --------KKPITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDD 1400 Query: 3089 KTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE-CVDKSKGQ 3147 K ++ S +IR Y + L I+G D+ Y+C+ATNK G ++ ++ +G+ Sbjct: 1401 KPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGE 1460 Query: 3148 KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV 3207 P++ +++ E ++D + F V P +++W+ +P+R R+ + + Sbjct: 1461 APKYVEPLKSDEIVED---SSFTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDSS 1517 Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239 L I T D G Y N +G+ + A + Sbjct: 1518 TLVITKTVPDDEGSYKIVLSNPFGKAVSEAEL 1549 Score = 87.0 bits (206), Expect = 3e-16 Identities = 120/494 (24%), Positives = 198/494 (40%), Gaps = 74/494 (14%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P+F P+K+ E+ EG V + T P + ++W+ + + + R T D Sbjct: 1994 EPPRFVTPLKDQELEEGSTVDMLVE-TDGTSP-IHIKWFKDNKELVPDERHTFTKDGNKH 2051 Query: 2036 ALDILYAYAEDTGTYM-CKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094 + I ED Y A N GEAVT + V V+ +K+ E+ Sbjct: 2052 TMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVE--------------VKEAAEVTPV 2097 Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154 E + ++ P P+ + L ++ EGD EC + P + W+ + + Sbjct: 2098 E--EVVDAAVPA--PIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLLEE 2151 Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL-KVAGHRNIILDTQH 2213 R I+Y D T + ++ EA C + +AG ++ Sbjct: 2152 DER-------------IMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDV------ 2192 Query: 2214 PNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPN 2273 T + VEE IS P L+ T EG F+ +V +P Sbjct: 2193 ---------------KTELIVEEG-ISLPVIKEGLKDT-EANEGDVVRFDIRVAGKPEPV 2235 Query: 2274 LRIEFYHNGKALQSAARFHITFDFG-----YVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328 +E++ N + L + +F I D SL I+ C PED YSV A+N G +S Sbjct: 2236 --VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSS 2293 Query: 2329 AISMTVTAKGSIISESQRPEGLEKIREL-ESAEPFKRPEIPEPVTRQRPVFTQPLQNIDN 2387 + V +K + +Q + L E+ E P T+ PVF + ++NI+ Sbjct: 2294 KGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVPEEEAASPETK-APVFIETMKNIE- 2351 Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF--GYVSMTISHVRDED 2445 + EG+ A FD + V +P+ ++W+R E+LI D R ++ I + + D Sbjct: 2352 VMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGD 2409 Query: 2446 EGVYMCRASNLLGE 2459 G Y C A+N + E Sbjct: 2410 TGKYTCIAANDVDE 2423 Score = 86.2 bits (204), Expect = 6e-16 Identities = 86/337 (25%), Positives = 135/337 (40%), Gaps = 54/337 (16%) Query: 259 SLGPVSPPKIAQKPRNSKLQ--EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316 S P KP N ++ EG A+ + +SG P V W+K+ L + T Sbjct: 1682 SFTPAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEEDERVSYET 1741 Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376 + TL +++ + D Y C+VT+ +V+ TE V Sbjct: 1742 DGDQHTLIIQSAELDDEAEYK--------CVVTNIAGSVDVKTELIV------------- 1780 Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ----- 431 EE I + P + +D + EG++ RFD RV G+P P W R Sbjct: 1781 ---EEGISL------PVIKEGLKDTEANEGEIVRFDIRVAGKPEP---WLNGSRMTSLWK 1828 Query: 432 ----IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK-- 485 I DD + K + +L+I D V + VA N++G+ + +L V + Sbjct: 1829 ILFIIIDDVDDK----DKELFSLVIEGCAPDDDAVYSVVAMNEAGKDTSKGKLLVHSRPK 1884 Query: 486 ----EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541 + P+ + V E PV L A V +TW KD ++ + + I T Sbjct: 1885 QEQPTEPAGPRITKELVDAEVEETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKT 1944 Query: 542 DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 D +STL I ++ D Y CT +N G T+T A + Sbjct: 1945 DETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEV 1981 Score = 85.8 bits (203), Expect = 8e-16 Identities = 205/965 (21%), Positives = 365/965 (37%), Gaps = 166/965 (17%) Query: 1304 DITVMQAPQF--SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361 D + + P F S + E E ++ L +Q G VEW + P+ Sbjct: 62 DAMLKEEPTFLESDEIKPFEVTEEGDIKLT--VQVTGKPQPSVEWLKDDVPVSPDEHITI 119 Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421 E D +L + +D G YT + +N+ G + + V + I P K Sbjct: 120 TEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTI-----PKDAVKP 174 Query: 1422 QYLEDTS--RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVE 1479 +++ED S ++ TD D +T+K + G K EP +V Sbjct: 175 KFIEDGSFVPFQSTDEGDVRLTVK-------------VTG-------KPEP------EVT 208 Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539 W K+G+PV H L I + +DSG Y C + VG + + S Sbjct: 209 WTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESE 268 Query: 1540 TDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599 + ++ L+ E+R K+ V+E EG+ R Sbjct: 269 GPAPKESEKRKLLKG----EERPKFVSDSTVEEFKIT-------------DEGEL----R 307 Query: 1600 RLIPVSDATL-KVEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPEDSGTYTCRAINA 1657 + V+ +VEW ++K LK R + G V L I DSG Y C+ + Sbjct: 308 LTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSD 367 Query: 1658 LGEAVTSGIAIVH-----SKKSIYL-ESQH--------------EGALP-RLNQLED-TS 1695 +G + S + +KK I + E++H E +P ++ +E Sbjct: 368 VGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVPEEQVMPTKVKPVETKVD 427 Query: 1696 KYQRHSAQDEVITQAPVF--TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753 K ++ D ++ + P F + +K V E A++ G P+ VEW ++ VP+ Sbjct: 428 KPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQV--TGKPQPSVEWFKDDVPV 485 Query: 1754 EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ 1813 +T + G +L +K +D GTY T+ V ++A L + Sbjct: 486 SPDEHITITEEDGTYSLVIKEPTKKDEGTY---------------TVEVSNEAGLGRRTF 530 Query: 1814 HESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPD 1873 S ++D+ + ++ V+ + F+ P + ++ ++ P+ Sbjct: 531 DVS-------VDDTRKTIPKDAVKPKFIEDGSFV-----PFQSTDEGDVRLTVKVTGKPE 578 Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933 P V W +GK + + L I +DSG Y C +++G++ + Sbjct: 579 PE--VTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFS 636 Query: 1934 LNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGH 1993 ++++SK ++S EK + + + R K FV + ++ ++T+ Sbjct: 637 VDIESKGPATKES------EKKKPRKGEERPK-------FVSDST-----LEEFKITDEG 678 Query: 1994 PVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR-FKTTYDFGYVALDILYAYAEDTGTYMC 2052 + L +T P VEW + + +++ +R + D G V L I A D+G Y C Sbjct: 679 ELRLTVKVT--GKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKC 736 Query: 2053 KATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFL 2112 K T+ VG + + V ++ + ++ KK+ E++ P +E+ Sbjct: 737 KVTSDVGTSTKSFDVTIEG---------ERRKAKKLIEVDDTVAPHFVED---------- 777 Query: 2113 TALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR-AGHRYRTTHDFGYVALDI 2171 T++ E GD V P W + + I +Y + L + Sbjct: 778 TSIAPFELTDSGD---VRLSVRVAGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIV 834 Query: 2172 LYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE-AQGHST 2230 D GTY C ATNK G T + + G +DT P E +++E +G S Sbjct: 835 KSPSPSDQGTYKCTATNKGGTVTRTFQVNMEG-----IDT-GPQIQEYSKEIEVVEGSSV 888 Query: 2231 RIEVE 2235 IE + Sbjct: 889 TIECQ 893 Score = 85.8 bits (203), Expect = 8e-16 Identities = 161/749 (21%), Positives = 284/749 (37%), Gaps = 110/749 (14%) Query: 2797 VEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGS 2856 V+ + P ++ W + KP+ + H L I +DSG Y C T+ G Sbjct: 197 VKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGK 256 Query: 2857 ATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIP 2916 +T + S + +++ P A +++E+ +L KG +P+++ Sbjct: 257 STRTFS--------VDIESEGP-------APKESEKRKLLKGEE---------RPKFVSD 292 Query: 2917 IAAEH-QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS-DFGFVTLDLV 2974 E ++ + L L +V K P+ +EW + K L++ R ++ D G V L + Sbjct: 293 STVEEFKITDEGELRLTVKVTGKPFPE--VEWTKDDKDLKEDDRVIISEQDDGIVVLRIK 350 Query: 2975 DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEK-IQNLEDSLR 3033 DV DSG+Y C+ + G + S V + ++ TE LEK I+++++ + Sbjct: 351 DVGAHDSGVYKCQVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVP 410 Query: 3034 KE--------PGQQPDDDTGRPPEFTTVFKDIVDISEG-QIAHYEA--------SLIPTG 3076 +E P + D + E + K+ E +I +E + TG Sbjct: 411 EEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQVTG 470 Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136 +EWF + + I G L I D GTY+ +N+ G + Sbjct: 471 KPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTF 530 Query: 3137 KLECVDKSK-----GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191 + D K KP+F + + TV P+ ++ W +G+P Sbjct: 531 DVSVDDTRKTIPKDAVKPKFIED-GSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKP 589 Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251 + ++ +L I DSG Y C + G+ +++ KG ES Sbjct: 590 VDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESKGPATKES 649 Query: 3252 LQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT-QIQDVTKLVEGQSAHFEARLVPVD 3310 +++ P E PKF++ + K+ + ++ Sbjct: 650 ------------------EKKKP-RKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGKP 690 Query: 3311 DPDLKVEWFYNGKKLPHGHR-YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTK 3369 P+ VEW + K L +R + D GIV+L I +SG Y+C T+ +G STK Sbjct: 691 FPE--VEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVG-TSTK 747 Query: 3370 ANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRR--KDTSVEEEKGKAPVFTVPLS 3427 + D + G +KL ++D++ +DTS+ AP Sbjct: 748 S-----------FDVTI-EGERRKAKKLIEVDDTVAPHFVEDTSI------APF------ 783 Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF--CDFGFVILEISPT 3485 L + + R+ +PN K W + + + S TF D ++ SP+ Sbjct: 784 ---ELTDSGDVRLSVRVAGKPEPNFK--WTKDDEDIDFRSSQYTFERVDDRLTLIVKSPS 838 Query: 3486 YPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514 P D G Y C A N G T + ++G Sbjct: 839 -PSDQGTYKCTATNKGGTVTRTFQVNMEG 866 Score = 83.4 bits (197), Expect = 4e-15 Identities = 88/360 (24%), Positives = 152/360 (42%), Gaps = 42/360 (11%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 G PEF K ++++ E Q E S+ TG I W G ++ RI TV+ Sbjct: 1159 GAAPEFIKPLK-VLEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDRITTVFDGE 1215 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 VL I + D G Y C A N +G+A +L V+++ KP+F + E + G Sbjct: 1216 TCVLNITVSCLDDEGEYKCLAMNDFGKAATVAEL-LVNEAL-VKPKFIETTHDTE-IITG 1272 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 +S F PD ++WYH + + R ++ L I + D G Y C Sbjct: 1273 ESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYKC 1330 Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284 N GED T ++K+ +E ++ P T PP+F Sbjct: 1331 IISNDAGEDMT---------------------VSKLTVIE------KKKPITDVGTPPEF 1363 Query: 3285 ITQI-QDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343 + + K+ +G E ++ +P +++WF + K + + R + I L Sbjct: 1364 SPHVGEGPLKISDGGDLTLEVKIT--GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLT 1421 Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDS 3403 I+ +++ +Y C ATNK G + N+ ++ L+ + + P+ +E L+ + +EDS Sbjct: 1422 IVGASPDDTAKYTCKATNKSGTTTRNINVDISA---LMPEGEAPKYVE-PLKSDEIVEDS 1477 Score = 81.8 bits (193), Expect = 1e-14 Identities = 138/607 (22%), Positives = 234/607 (38%), Gaps = 103/607 (16%) Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 +V W + ++ + NR+ D L I+ +D G+YT RN G Sbjct: 1924 SVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMG---------- 1973 Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195 DTS+ + E+ +E EP P FV PL + + EG + Sbjct: 1974 ------DTSTSAEVIVEELEAVESE--AEP-----------PRFVTPLKDQE-LEEGSTV 2013 Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY-TVRA 1254 + +E G + ++WF + + + R D + I T D Y V A Sbjct: 2014 DM--LVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVA 2071 Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFS 1314 N G A T A +++ + + + ++ + DAA + AP Sbjct: 2072 ENVAGEAVTDA--------EVIVEVKEAAEVTPVEEVVDAA------------VPAPIII 2111 Query: 1315 RALHN-IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373 + L++ I+ +EG +V LEC + G +V W+ + ++ R + D L + Sbjct: 2112 KPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQ 2169 Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKT 1433 S +D Y C TN G V K +LI+E + K + L+DT + Sbjct: 2170 SAELDDEAEYKCVVTNIAGS--------VDVKTELIVEEGISLPVIK-EGLKDTEA-NEG 2219 Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493 D++ RF R + G K EPV VEWFKN + + +F Sbjct: 2220 DVV--------RFDIR-------VAG-------KPEPV------VEWFKNDELLDDSGKF 2251 Query: 1494 RPIHDFGYVALDIIDLI-----AEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548 I D ++ L+ ED +Y+ A+N G D +L S + Q Sbjct: 2252 IIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQA 2311 Query: 1549 EAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDAT 1608 +A ++ L + + T+AP+ ++KN+E+ EG+ A F+ + V + + Sbjct: 2312 DAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPS 2371 Query: 1609 LKVEWYHNNKPLKSGSRFTETN--NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666 ++WY + + RF + L I + D+G YTC A N + E + Sbjct: 2372 --IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAV 2429 Query: 1667 AIVHSKK 1673 V K+ Sbjct: 2430 LTVKPKE 2436 Score = 81.0 bits (191), Expect = 2e-14 Identities = 204/918 (22%), Positives = 349/918 (38%), Gaps = 164/918 (17%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001 VEWLKD PV IT +L IK T D G YT N G + ++++ Sbjct: 102 VEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVD 161 Query: 1002 VTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSA 1061 T+K I P K +++ED S ++ +E G ++ T K+ Sbjct: 162 DTRKTI------PKDAVKPKFIEDGSFVPFQSTDE----------GDVRLTVKVT----- 200 Query: 1062 HFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVAR 1121 + EP+ V W +GK + ++ H L I +DSG Y Sbjct: 201 ---GKPEPE------VTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLT 251 Query: 1122 NAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQ 1181 + G++ + S+ +E+ S R L + E KFV +EE + Sbjct: 252 SDVGKSTRTFSVDIESEGPAPKESEKRKLLKGE---ERPKFVSDS-TVEEFKIT------ 301 Query: 1182 PLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR-FKTYYDFGFVALDII 1240 EG+ L ++ G P VEW + + + R + D G V L I Sbjct: 302 --------DEGE---LRLTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIK 350 Query: 1241 HATSADTGEYTVRAVNHLGSAHTSAIV------RVIERSDIVTDTQN------------- 1281 + D+G Y + + +G++ S V R ++ V +T++ Sbjct: 351 DVGAHDSGVYKCQVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVP 410 Query: 1282 -EQAI-EQIQLLEDAARRTKQVRE-DITVMQAPQF--SRALHNIETVEGTNVHLECRLQP 1336 EQ + +++ +E + +Q+ E D + + P F S + E E ++ + Q Sbjct: 411 EEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTA--QV 468 Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396 G VEWF + P+ E +L + +D G YT + +N+ G Sbjct: 469 TGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRR 528 Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQYLEDTS--RYKKTDIIDESVTIKPRFVTRPKSIE 1454 + + V + I P K +++ED S ++ TD D +T+K Sbjct: 529 TFDVSVDDTRKTI-----PKDAVKPKFIEDGSFVPFQSTDEGDVRLTVK----------- 572 Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514 + G K EP +V W K+G+PV H L I + +DS Sbjct: 573 --VTG-------KPEP------EVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDS 617 Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVT 1574 G Y C + VG + + S + ++ + + E+R K+ Sbjct: 618 GSYRCTLTSDVGKSTRTFSVDIESKGPATKESEKKKPRKG----EERPKF---------- 663 Query: 1575 TQAPICTTSLKNVEI-KEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSR-FTETNN 1631 + ++L+ +I EG+ R + V+ +VEW ++K LK +R + Sbjct: 664 ----VSDSTLEEFKITDEGEL----RLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQD 715 Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691 G V L I DSG Y C+ VTS + + +E + A +L ++ Sbjct: 716 DGIVVLRIKDVGAHDSGVYKCK--------VTSDVGTSTKSFDVTIEGERRKA-KKLIEV 766 Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751 +DT H +D I AP D+R++ A G P+ +W ++ Sbjct: 767 DDT--VAPHFVEDTSI--APFELTDSGDVRLSVRVA----------GKPEPNFKWTKDDE 812 Query: 1752 PIE-ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810 I+ S++ T + L +K +P D GTY C A N+ G T + F + + Sbjct: 813 DIDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGG---TVTRTFQVNMEGIDT 869 Query: 1811 ESQHESALQKIQQLEDSS 1828 Q + ++I+ +E SS Sbjct: 870 GPQIQEYSKEIEVVEGSS 887 Score = 79.8 bits (188), Expect = 5e-14 Identities = 51/227 (22%), Positives = 100/227 (44%), Gaps = 9/227 (3%) Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEP--LKDKIVAEGQAIEFSCKIVGKPLPT 4653 RC L + P+ P +E +K V E I+ + ++ GKP P+ Sbjct: 42 RCKTTASAKLACLQRIPEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKLTVQVTGKPQPS 101 Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713 V+W K D + P ++ ++ D Y+L I E +DEG Y N AG + V Sbjct: 102 VEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVD 161 Query: 4714 QPDQADNLPALTP--LRD--IVVYEGQ---PAQFKTQITSKIKPTIQWLREGALIPETPD 4766 + A+ P + D V ++ + ++T K +P + W ++G + + P+ Sbjct: 162 DTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKLPN 221 Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 ++ H+ + +L I +D+G++ C T+ G+ + + ++S+ Sbjct: 222 VELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESE 268 Score = 78.6 bits (185), Expect = 1e-13 Identities = 112/446 (25%), Positives = 179/446 (40%), Gaps = 65/446 (14%) Query: 904 ESTQKPEFKTPIKDQISIKEGGFAHFEAR--------LEPIGDSTLRVEWLKDGRPVEAS 955 + T+K K +K + I++G F F++ ++ G V W KDG+PV+ Sbjct: 161 DDTRKTIPKDAVKPKF-IEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKL 219 Query: 956 SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPG 1015 + LTI+ + D+G Y C + +G++T + ++ DI +E P Sbjct: 220 PNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSV------DIESEGPAPK 273 Query: 1016 GLEKIQYLEDASR---YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSD 1072 EK + L+ R S T EE KIT + G L+ T K+ + P+ Sbjct: 274 ESEKRKLLKGEERPKFVSDSTVEEFKITDE----GELRLTVKVT--------GKPFPE-- 319 Query: 1073 LTMTVEWYFNGKQITSANR-IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSA 1131 VEW + K + +R I + D G V L I V A DSGVY + G + S Sbjct: 320 ----VEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTSTKSF 375 Query: 1132 SMTVE-----TRSSIDTSSIHRGLYEKTRHIEE---------------SKFVEPMYQIEE 1171 +T+E + I+ L ++ +H++E V+ QIEE Sbjct: 376 DVTIEGERRKAKKLIEVDETEH-LEKRIKHVKEPVPEEQVMPTKVKPVETKVDKPRQIEE 434 Query: 1172 IS---KSKPVFVQPLS-NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227 + K +P F++ P V+E +I + ++ G P VEWF + V+ Sbjct: 435 VDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQV--TGKPQPSVEWFKDDVPVSPDEHIT 492 Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAIE 1286 + G +L I T D G YTV N G + V V + R I D + IE Sbjct: 493 ITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIE 552 Query: 1287 QIQLLEDAARRTKQVREDITVMQAPQ 1312 + + VR + V P+ Sbjct: 553 DGSFVPFQSTDEGDVRLTVKVTGKPE 578 Score = 78.6 bits (185), Expect = 1e-13 Identities = 45/194 (23%), Positives = 92/194 (47%), Gaps = 7/194 (3%) Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686 + +K V E I+ + ++ GKP P+V+W+K D + P ++ ++ Y+L I E Sbjct: 449 DEIKPFEVTEEGDIKMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPT 508 Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP--LRD--IVVYEGQ---PAQ 4739 +DEG Y N AG + V + A+ P + D V ++ + Sbjct: 509 KKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVR 568 Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799 ++T K +P + W ++G + + P+ ++ H+ + +L I +D+G++ C T+ Sbjct: 569 LTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDV 628 Query: 4800 GQVETSAKLVVKSK 4813 G+ + + ++SK Sbjct: 629 GKSTRTFSVDIESK 642 Score = 78.6 bits (185), Expect = 1e-13 Identities = 101/455 (22%), Positives = 186/455 (40%), Gaps = 61/455 (13%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 +P EP+ P + +A + + V+WT+ +V N+ +++ +E Sbjct: 1887 QPTEPAGPRITKELVDAEVEETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKTDE 1946 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184 + +L I + DEG YTCT RN+ G+ S + E + + Sbjct: 1947 TSS--TLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPLKD 2004 Query: 185 -------TVEH--KAYGTQGYTTEQSRQTQKV------AYT-NGTDHSSTDD---FKVDT 225 TV+ + GT + + +++ +T +G H+ T + + Sbjct: 2005 QELEEGSTVDMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEA 2064 Query: 226 FEYRLLREVSFRESIT--KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQ--EGA 281 Y+++ E E++T + V + T ++ + P I KP N ++ EG Sbjct: 2065 MYYKVVAENVAGEAVTDAEVIVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGD 2124 Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAE 341 + + +SG P +V W+K+ L + T + TL +++ + D Y Sbjct: 2125 SVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYK---- 2180 Query: 342 NPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDR 401 C+VT+ +V+ TE V EE I + P + +D Sbjct: 2181 ----CVVTNIAGSVDVKTELIV----------------EEGISL------PVIKEGLKDT 2214 Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-----HALMITNVT 456 + EG + RFD RV G+P P V WF ND ++ DD I++++ + +L+I Sbjct: 2215 EANEGDVVRFDIRVAGKPEPVVEWFKND-ELLDDSGKFIIIDDVDDKDKELFSLVIEGCA 2273 Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491 D V + VA N++G+ + + +L V K + AP Sbjct: 2274 PEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAP 2308 Score = 77.8 bits (183), Expect = 2e-13 Identities = 76/342 (22%), Positives = 135/342 (39%), Gaps = 14/342 (4%) Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 G + I+ +I + PK + ++ ++ E + V+ +G P P V WFK + Sbjct: 1442 GTTTRNINVDISALMPEGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQWFKENKP 1501 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365 + ++ II + +TL + T D G Y ++ NP G V+ L V + +E+ +D Sbjct: 1502 VREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEA--ED 1559 Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR-PYPEVT 424 + +TE I + P V + +D ++T + + GR P+ V Sbjct: 1560 EGIIPKVTPTPGKTEITIPGQKPKFGPVEVDIKGLKDKERERLTS-EASIAGRKPFGAVD 1618 Query: 425 WFINDRQIRDDYNHKILVNESGNHALMITNVTL---SDSGVVTCVARNKSGETAFQCRLN 481 I +D + E A +++ ++ ++ K L Sbjct: 1619 MSIT--APGEDKKPTVTEAEFTPVAFKPVEISVPIGDEAPFISLKGAKKPDLPVLAKPLE 1676 Query: 482 VIEKEQVV----APKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536 VI AP ++ + ++V EG+ L G P + W KD + + Sbjct: 1677 VIMPVSFTPAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEEDER 1736 Query: 537 LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + TDG TL I A+ D A Y+C N+AGS + L Sbjct: 1737 VSYETDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL 1778 Score = 77.8 bits (183), Expect = 2e-13 Identities = 101/484 (20%), Positives = 190/484 (39%), Gaps = 47/484 (9%) Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964 ++E P ++ P+ + +L EG + + VE + I+W+ + K L R T Sbjct: 1990 ESEAEPPRFVTPLK-DQELEEGSTVDM--LVETDGTSPIHIKWFKDNKELVPDERHTFTK 2046 Query: 2965 DFGFVTLDLVDVYERDSGIY-TCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023 D T+ + V D +Y A N GEA T + V Sbjct: 2047 DGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEV---------------------- 2084 Query: 3024 KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIE 3083 I ++++ P ++ D P D +D+ EG E +I G + V+ Sbjct: 2085 -IVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRLEC-VISGGPDAQVL- 2141 Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143 W+ + +E RI L I + D Y C TN G + VK E + + Sbjct: 2142 WYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGS--VDVKTELIVE 2199 Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203 P +++ E +G F+ V P+ +EW+ N + + S + + D Sbjct: 2200 EGISLPVIKEGLKDTEA-NEGDVVRFDIRVA--GKPEPVVEWFKNDELLDDSGKFIIIDD 2256 Query: 3204 FG-----FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLA 3258 L I D Y A N+ G+D ++ + K + Q D+ Sbjct: 2257 VDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPA-QADAAT 2315 Query: 3259 KIRE--LESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316 I E +E++ ++ ++P + P FI ++++ +++EG+ A F+ + V +P + Sbjct: 2316 PILEPLVETIPEVPEEEAASPETKAPVFIETMKNI-EVMEGEEARFDVHVDGVPEPS--I 2372 Query: 3317 EWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEE--NSGEYECVATNKLGRDSTKANLKC 3374 +W+ + +P R+ I ++ + ++G+Y C+A N + + +A L Sbjct: 2373 DWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTV 2432 Query: 3375 TSKE 3378 KE Sbjct: 2433 KPKE 2436 Score = 77.4 bits (182), Expect = 3e-13 Identities = 58/238 (24%), Positives = 108/238 (45%), Gaps = 14/238 (5%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG---- 1766 PV +KD E F+ R+ G P+ VEW +N ++ S + + D Sbjct: 2205 PVIKEGLKDTEANEGDVVRFDIRV--AGKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDK 2262 Query: 1767 -YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825 +L ++ PED Y+ A+NE G+ + L V SK + +Q ++A ++ L Sbjct: 2263 ELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLV 2322 Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885 ++ E+ +AP FI + ++ EG+ A ++ ++ P+P+ ++WY + Sbjct: 2323 ETIPEVPEEEAASPETKAPVFIETMKN-IEVMEGEEARFDVHVDGVPEPS--IDWYRGEE 2379 Query: 1886 VLQSGHRY---RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 ++ R+ + F + T G D+G+YTC A N++ + L V+ KE Sbjct: 2380 LIPDEGRFVHIDAVKEEIFTLVIENTKLG-DTGKYTCIAANDVDEITCEAVLTVKPKE 2436 Score = 73.3 bits (172), Expect = 4e-12 Identities = 89/383 (23%), Positives = 156/383 (40%), Gaps = 29/383 (7%) Query: 2868 DKNIYFDTQHPQGKAGLEAVEQAEEAR---LAKGRRPSVP-DTEYPKPEWI-IPIAAEH- 2921 D+ I +DT Q +++ E +EA + SV TE E I +P+ E Sbjct: 2152 DERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISLPVIKEGL 2211 Query: 2922 ---QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVY- 2977 + EG V+ + +V K +P +EW+ N ++L+ +F + D +L + Sbjct: 2212 KDTEANEGDVVRFDIRVAGKPEP--VVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVI 2269 Query: 2978 ----ERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLR 3033 D +Y+ A N+ G+ + + SK Q T LE + + Sbjct: 2270 EGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVP 2329 Query: 3034 KEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA 3093 +E P+ + P F K+I ++ EG+ A ++ + + S I+W+ + I Sbjct: 2330 EEEAASPET---KAPVFIETMKNI-EVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPD 2383 Query: 3094 SHRIRTVYAFG--MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF 3151 R + A + L I TK D+G Y+C A N EI+ + K K P F Sbjct: 2384 EGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVD--EITCEAVLTVKPKEIAPEF 2441 Query: 3152 TTHIQNIE-GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLD 3210 + + G + TV P K+EW+ + +P++ + R++ + L Sbjct: 2442 QKEPEKSTFDVNTGDDVSLDLTVT--GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLK 2499 Query: 3211 IAYTQNHDSGEYVCRAYNKYGED 3233 I + DSG+Y A + G D Sbjct: 2500 IKGGKPDDSGKYTVVAESPAGRD 2522 Score = 72.9 bits (171), Expect = 6e-12 Identities = 62/231 (26%), Positives = 98/231 (42%), Gaps = 16/231 (6%) Query: 3292 TKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG-----IVILDILY 3346 T+ EG F+ R+ +P VEWF N + L ++ D + L I Sbjct: 2214 TEANEGDVVRFDIRVAGKPEP--VVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEG 2271 Query: 3347 CYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVR 3406 C E+ Y VA N+ G+DS+K L SK + + P + L+ L +++ Sbjct: 2272 CAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKP----EQEAPAQADAATPILEPLVETIPE 2327 Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466 + + KAPVF + NIE + EGE A F+ + +P+ ++WY + + Sbjct: 2328 VPEEEAASPETKAPVFIETMKNIE-VMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDE 2384 Query: 3467 SRFRTF--CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 RF L I T D+G+Y C A N+ E A + V+ K Sbjct: 2385 GRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435 Score = 70.9 bits (166), Expect = 2e-11 Identities = 164/744 (22%), Positives = 267/744 (35%), Gaps = 114/744 (15%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133 TG + W +GK ++ + + +L I DSG+Y C T+ G++ Sbjct: 200 TGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTR 259 Query: 3134 -ISVKLECVDKS----------KGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181 SV +E + KG+ +P+F + +E K TV P Sbjct: 260 TFSVDIESEGPAPKESEKRKLLKGEERPKFVSD-STVEEFKITDEGELRLTVKVTGKPFP 318 Query: 3182 KIEWYHNGQPMRHSTR-IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240 ++EW + + ++ R I + D G VVL I HDSG Y C+ + G + Sbjct: 319 EVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTSTKSFDVT 378 Query: 3241 CYG---KGGVYLESLQPDSLAK-IRELESLQGAQQQTPSTPSAEPPKFIT--QIQDVTKL 3294 G K +E + + L K I+ ++ +Q P+ K QI++V + Sbjct: 379 IEGERRKAKKLIEVDETEHLEKRIKHVKEPVPEEQVMPTKVKPVETKVDKPRQIEEVDAM 438 Query: 3295 VEGQSAHFEA-RLVP---VDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEE 3350 ++ + E+ + P ++ D+K+ GK P F D V D E Sbjct: 439 LKEEPTFLESDEIKPFEVTEEGDIKMTAQVTGKPQPS---VEWFKDDVPVSPDEHITITE 495 Query: 3351 NSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDT 3410 G Y V +D ++ ++ E GL + R D Sbjct: 496 EDGTYSLVIKEPTKKDEGTYTVEVSN--------------EAGLGR---------RTFDV 532 Query: 3411 SVEEEKGKAPVFTVPLSNIEN-----LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKA 3465 SV++ + P V IE+ + + + T P +V W +GK + Sbjct: 533 SVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDK 592 Query: 3466 GSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLP 3525 IL I P+DSG Y C ++ G++ T S+ +ES+ P Sbjct: 593 LPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVD--------IESKGP 644 Query: 3526 KGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL-IPV 3584 E K E V T E EF T E RL + V Sbjct: 645 ATKESEKKKPRKGEERPKFVSDSTLE-------EFKITDEG-----------ELRLTVKV 686 Query: 3585 NDSSM-RVEWFHNGKPLLTGSRVK-TINDFGFVILEIGGVYQRDAGLYTCKATNRHGEAT 3642 VEW + K L +RV + D G V+L I V D+G+Y CK T+ G +T Sbjct: 687 TGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTST 746 Query: 3643 VSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIK 3702 S + ++G + + + ++++T+ +ED P Sbjct: 747 KSFDVTIEGE-------------RRKAKKLIEVDDTVAPH---FVEDTSIAP-------- 782 Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GFIALDIDYIY 3761 ++ + G V RV G P W + S +T + L + Sbjct: 783 --FELTDSGDVRLSVRV--AGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIVKSPS 838 Query: 3762 ARDAGEYTCRATNKWGSATTTAKI 3785 D G Y C ATNK G+ T T ++ Sbjct: 839 PSDQGTYKCTATNKGGTVTRTFQV 862 Score = 68.9 bits (161), Expect = 9e-11 Identities = 58/245 (23%), Positives = 101/245 (41%), Gaps = 12/245 (4%) Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702 LK A EG + F+ R+ G P +EW KN + ++ S +F I ++ SL Sbjct: 2211 LKDTEANEGDVVRFDIRV--AGKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLV 2268 Query: 703 I-----QDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQ 757 I +D Y+ A++ G +K L V + E +Q ++ L + Sbjct: 2269 IEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEV 2328 Query: 758 HQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASS 817 +E ++ P FI ++++ E+ EG A F+ + V +P+ ++WY+ I Sbjct: 2329 PEEEAASPETKAPVFIETMKNI-EVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEG 2385 Query: 818 RITSI--FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875 R I +L I + + D G YT A N + E A + V + P Sbjct: 2386 RFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPKEIAPEFQKEP 2445 Query: 876 EQRRY 880 E+ + Sbjct: 2446 EKSTF 2450 Score = 67.3 bits (157), Expect = 3e-10 Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 3/165 (1%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 +G +EW+ + + + L I +D+GTY C N G Sbjct: 1088 SGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYKCVTKNDSGTFTQ 1147 Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194 + V+K +G P F ++ +E + + Q EC+V +P +I W G ++ Sbjct: 1148 MFDITIVEKPEGAAPEFIKPLKVLE-VFETQPVRLECSVTGTPEP--QITWLKGGDVVKE 1204 Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239 RI TV D VL+I + D GEY C A N +G+ T A + Sbjct: 1205 DDRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAEL 1249 Score = 65.7 bits (153), Expect = 9e-10 Identities = 66/246 (26%), Positives = 105/246 (42%), Gaps = 19/246 (7%) Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746 I +E + P +KD + EG V FD RV G P ++WF N + Sbjct: 2197 IVEEGISLPVIKEGLKDT-EANEGDVVRFDIRV--AGKPEPVVEWFKNDELLDDSGKFII 2253 Query: 3747 LNDFG-----FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP- 3800 ++D +L I+ D Y+ A N+ G ++ K+ ++K E + P Sbjct: 2254 IDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKP----EQEAPA 2309 Query: 3801 QGMSGEKIKELERGRISDAPKEEPIV--STPPKFITQIKSHTVEESEGVRFECRVEPKED 3858 Q + I E I + P+EE + P FI +K+ V E E RF+ V+ + Sbjct: 2310 QADAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPE 2369 Query: 3859 PKLRIEWYRNGKLLPSGHRYRTV--YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTK 3916 P I+WYR +L+P R+ + +L I D+G+Y C A ND E + Sbjct: 2370 PS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCE 2427 Query: 3917 ATISCK 3922 A ++ K Sbjct: 2428 AVLTVK 2433 Score = 65.3 bits (152), Expect = 1e-09 Identities = 71/278 (25%), Positives = 106/278 (38%), Gaps = 32/278 (11%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V + P F TP+KDQ ++EG + +E G S + ++W KD + + R T Sbjct: 1989 VESEAEPPRFVTPLKDQ-ELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFT 2045 Query: 962 FNFGYVALTIKSVTVHD-AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020 + +TI VT+ D A +Y A N G+A T A ++I E + + + Sbjct: 2046 KDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDA--------EVIVEVKEAAEVTPV 2097 Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080 + + DA+ P + PL ++EG S E + D V WY Sbjct: 2098 EEVVDAA------------VPAPIIIKPLNDEIDVLEGDSVRLECVISGGPD--AQVLWY 2143 Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140 + + RI D L I S +D Y V N AG + + VE Sbjct: 2144 KDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVE--EG 2201 Query: 1141 IDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPV 1178 I I GL K E V + I K +PV Sbjct: 2202 ISLPVIKEGL--KDTEANEGDVVR--FDIRVAGKPEPV 2235 Score = 64.9 bits (151), Expect = 2e-09 Identities = 94/395 (23%), Positives = 161/395 (40%), Gaps = 56/395 (14%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P V W KDG+P+ + L I +D+GSY + +G++ T S Sbjct: 203 PEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFS 262 Query: 860 IRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQI 919 + + + + E+R+ ++ V +ST + EFK I D+ Sbjct: 263 VDIESEGPAPKE---SEKRKLLK------------GEERPKFVSDSTVE-EFK--ITDEG 304 Query: 920 SIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHD 978 ++ ++ G VEW KD + ++ R I + + G V L IK V HD Sbjct: 305 ELR--------LTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHD 356 Query: 979 AGHYTCRAYNAIGQATTSANLTIV---TKKDIIAESQHPGGLEK-IQYLEDASRYSKRTE 1034 +G Y C+ + +G +T S ++TI K + E LEK I+++++ + Sbjct: 357 SGVYKCQVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVPEEQVMP 416 Query: 1035 EEVKITQ----KPRFL----GPLKGTNKIVEGQSAH-FEARVEPQSDLTM--------TV 1077 +VK + KPR + LK +E FE E +T +V Sbjct: 417 TKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQVTGKPQPSV 476 Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV-E 1136 EW+ + ++ I + G +L I +D G YTV N AG + + ++V + Sbjct: 477 EWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDD 536 Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEE 1171 TR +I ++ K + IE+ FV P +E Sbjct: 537 TRKTIPKDAV------KPKFIEDGSFV-PFQSTDE 564 Score = 64.5 bits (150), Expect = 2e-09 Identities = 60/236 (25%), Positives = 98/236 (41%), Gaps = 40/236 (16%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP F P+K + V E Q E + G P+ ++ WL+ G ++ +R+TT+ D Sbjct: 1161 APEFIKPLKVLEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDRITTVFDGETCV 1218 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829 LN+ +D G Y C A+N+ G+A T + L V AL K + +E + Sbjct: 1219 LNITVSCLDDEGEYKCLAMNDFGKAATVAELLV------------NEALVKPKFIETT-- 1264 Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889 D E+ ++ F + G P PD V+WY ++ Sbjct: 1265 ----HDTEIITGESVWFRVKYEG----------------SPTPD----VDWYHEDTLVSD 1300 Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945 R+ + + + L I V D G Y C N+ G+ ++ +L V K+ I D Sbjct: 1301 TGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITD 1356 Score = 64.1 bits (149), Expect = 3e-09 Identities = 62/239 (25%), Positives = 108/239 (45%), Gaps = 40/239 (16%) Query: 1837 EVAVNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893 E+ VN+A P+FI + T++ G+S + + E P P+ V+WY ++ R+ Sbjct: 1248 ELLVNEALVKPKFI-ETTHDTEIITGESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRF 1304 Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953 + + + L I V D G Y C N+ G+ ++ +L V +E Sbjct: 1305 LINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTV---------------IE 1349 Query: 1954 KIQYLEDDSRYKRAVQDDSFVVE-KPQFGK-PIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011 K K+ + D E P G+ P+K +++G + LE +T +P + Sbjct: 1350 K----------KKPITDVGTPPEFSPHVGEGPLK---ISDGGDLTLEVKIT--GEPKPEI 1394 Query: 2012 EWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 +W+ + +PV+ + + Y +L I+ A +DT Y CKATN G TT ++ VD Sbjct: 1395 QWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG--TTTRNINVD 1451 Score = 62.9 bits (146), Expect = 6e-09 Identities = 156/701 (22%), Positives = 268/701 (38%), Gaps = 96/701 (13%) Query: 3662 PSHFKSGTESIQKLEET-LHKRE-EITIEDEKPNPPRFTVE---IKDNIDVPEGGPVHFD 3716 P+ GT +++ E L +R +++++D + P+ V+ I+D VP D Sbjct: 133 PTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGD 192 Query: 3717 CR--VEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774 R V+ G P + W +G+P V + L I D+G Y C T+ Sbjct: 193 VRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTS 252 Query: 3775 KWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFIT 3834 G +T T + +ES+ P EK ++L +G EE PKF++ Sbjct: 253 DVGKSTRTFSVD--------IESEGPAPKESEK-RKLLKG-------EER-----PKFVS 291 Query: 3835 Q--IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR-TVYDMGFVSLDI 3891 ++ + + +R +V K P+ +EW ++ K L R + D G V L I Sbjct: 292 DSTVEEFKITDEGELRLTVKVTGKPFPE--VEWTKDDKDLKEDDRVIISEQDDGIVVLRI 349 Query: 3892 LYVYAEDSGEYICRAVNDFGEDFTKA---TI-----SCKKLPDIILQNQVPRGMKRSEAL 3943 V A DSG Y C+ +D G TK+ TI KKL ++ + + +K + Sbjct: 350 KDVGAHDSGVYKCQVSSDVGTS-TKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEP 408 Query: 3944 TQMEATIKKYTSEVYLTED---DLYDVDK--KQPPRFVTQIQSQT-SLVEMETTKFECQL 3997 E + V D + +VD K+ P F+ + + + E K Q+ Sbjct: 409 VPEEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQV 468 Query: 3998 APVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057 G P VEWF + P+ T + G ++ +D G Y +N G+ Sbjct: 469 --TGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLG 526 Query: 4058 ETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLP 4117 +D + K+I K +A V P+ + + S FV Sbjct: 527 RR------------TFDVSVDDTRKTIPK----DA---VKPKFIEDGS-------FVPFQ 560 Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYD 4176 + +EG+ R +VTG P+P V W +G + +L + + Y I + D Sbjct: 561 ---STDEGD-VRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDD 616 Query: 4177 TGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFE 4236 +G + + + + K PR +R + + T E Sbjct: 617 SGSYRCTLTSDVGKSTRTFSVDIESKGPATKESEKKKPR------KGEERPKFVSDSTLE 670 Query: 4237 ERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLR 4296 E ++ +G + R +K PE EW + K K + N++ E + I R++ Sbjct: 671 EFKITD-EGEL--RLTVKVTGKPFPEVEWTKDDKDLKED---NRVIISEQDDGIVVLRIK 724 Query: 4297 E-STHQYAIPGDKVTSN--TVAKSMAQRYEDNLDQTEEVTE 4334 + H + KVTS+ T KS E + +++ E Sbjct: 725 DVGAHDSGVYKCKVTSDVGTSTKSFDVTIEGERRKAKKLIE 765 Score = 62.9 bits (146), Expect = 6e-09 Identities = 66/243 (27%), Positives = 108/243 (44%), Gaps = 33/243 (13%) Query: 904 ESTQKPEFKTPIKDQISIKEGGFAHFEAR--------LEPIGDSTLRVEWLKDGRPVEAS 955 + T+K K +K + I++G F F++ ++ G V W KDG+PV+ Sbjct: 535 DDTRKTIPKDAVKPKF-IEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKL 593 Query: 956 SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPG 1015 + LTI+ + D+G Y C + +G++T + ++ I +K ES+ Sbjct: 594 PNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESKGPATKESEK-- 651 Query: 1016 GLEKIQYLEDASRY-SKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLT 1074 +K + E+ ++ S T EE KIT + G L+ T K+ + P+ Sbjct: 652 --KKPRKGEERPKFVSDSTLEEFKITDE----GELRLTVKVT--------GKPFPE---- 693 Query: 1075 MTVEWYFNGKQITSANR-IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133 VEW + K + NR I + D G V L I V A DSGVY + G + S + Sbjct: 694 --VEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFDV 751 Query: 1134 TVE 1136 T+E Sbjct: 752 TIE 754 Score = 62.5 bits (145), Expect = 8e-09 Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 7/102 (6%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG---- 1766 PV P+K + + E AA F+ R+ G P+ VEW ++G ++ R + D Sbjct: 967 PVIIQPLKSLEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDK 1024 Query: 1767 -YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807 +L ++ V PED+G Y C A+NE G+A +++TL V +K S Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKIS 1066 Score = 60.5 bits (140), Expect = 3e-08 Identities = 58/207 (28%), Positives = 83/207 (40%), Gaps = 14/207 (6%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFG-----FVILEIGGVYQRDAGLYTCKATNRHGEATVSC 3645 VEWF N + L + I+D L I G D +Y+ A N G+ + Sbjct: 2236 VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKG 2295 Query: 3646 KLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNI 3705 KL V + E + P+ + T ++ L ET+ + E + P F +E NI Sbjct: 2296 KLLVNSKP----EQEAPAQADAATPILEPLVETIPEVPEEEAASPETKAPVF-IETMKNI 2350 Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VH-TLNDFGFIALDIDYIYAR 3763 +V EG FD V+ V +P+ IDW+ R VH L I+ Sbjct: 2351 EVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLG 2408 Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAK 3790 D G+YTC A N T A +T K Sbjct: 2409 DTGKYTCIAANDVDEITCEAVLTVKPK 2435 Score = 60.1 bits (139), Expect = 4e-08 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 2/93 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P+F KP+K EV E PV LE ++T +P ++ W G V++ R T +D L Sbjct: 1162 PEFIKPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITTVFDGETCVL 1219 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 +I + +D G Y C A N G+A T + + V+ Sbjct: 1220 NITVSCLDDEGEYKCLAMNDFGKAATVAELLVN 1252 Score = 59.7 bits (138), Expect = 6e-08 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 3/103 (2%) Query: 3410 TSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRF 3469 T VE+ +G AP F PL +E + E + E +T T +P ++ W G +K R Sbjct: 1152 TIVEKPEGAAPEFIKPLKVLE-VFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRI 1208 Query: 3470 RTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 T D +L I+ + +D GEY C A N++G+A T A + V Sbjct: 1209 TTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 59.7 bits (138), Expect = 6e-08 Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P+FI +K V E++ VR EC V +P+ I W + G ++ R TV+D L Sbjct: 1162 PEFIKPLKVLEVFETQPVRLECSVTGTPEPQ--ITWLKGGDVVKEDDRITTVFDGETCVL 1219 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 +I +D GEY C A+NDFG+ T A + Sbjct: 1220 NITVSCLDDEGEYKCLAMNDFGKAATVAEL 1249 Score = 59.7 bits (138), Expect = 6e-08 Identities = 61/229 (26%), Positives = 90/229 (39%), Gaps = 16/229 (6%) Query: 3983 TSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG-----YVAMNFGW 4037 T E + +F+ ++A G P VEWF N + L +F I D ++ Sbjct: 2214 TEANEGDVVRFDIRVA--GKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEG 2271 Query: 4038 VYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVT 4097 PED Y A N G D +K + KP +Q +E + +E +V Sbjct: 2272 CAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPL--VETIPEVP 2329 Query: 4098 PEQVVE-ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156 E+ E+KA PVF+ + V EGE ARF V G P+P + W I + R Sbjct: 2330 EEEAASPETKA---PVFIETMKNIEVMEGEEARFDVHVDGVPEPSIDWYRGEELIPDEGR 2386 Query: 4157 Y---KLTYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202 + + ++ I T+ DTGK I L V P+ Sbjct: 2387 FVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435 Score = 59.3 bits (137), Expect = 8e-08 Identities = 57/228 (25%), Positives = 98/228 (42%), Gaps = 26/228 (11%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 +E E + PPRFVT L+ + EG T + VE + I+++ + K L R Sbjct: 1986 LEAVESEAEPPRFVTPLK-DQELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERH 2042 Query: 2292 HITFDFGYVSLDIQHCVPED-AGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350 T D ++ I ED A Y V A N G + + V K E+ + Sbjct: 2043 TFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK-----EAAEVTPV 2097 Query: 2351 EKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKV 2410 E++ +++A P P+ +PL + ++ EG + +C + G P +V Sbjct: 2098 EEV--VDAAVP-------------APIIIKPLNDEIDVLEGDSVRLEC--VISGGPDAQV 2140 Query: 2411 EWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 W++++ L+E+ RI D ++ I +DE Y C +N+ G Sbjct: 2141 LWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188 Score = 58.8 bits (136), Expect = 1e-07 Identities = 57/258 (22%), Positives = 116/258 (44%), Gaps = 41/258 (15%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 KP F++ ++ + G+++ + E G PT V+W+H V+ RF Sbjct: 1257 KPKFIET-THDTEIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRF--------- 1304 Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295 +I+ T DT + V + + I+ D + + ++ ++E Sbjct: 1305 ---LIN-TEEDTSTLIIEDVKPIDKGNYKCIIS--------NDAGEDMTVSKLTVIE--- 1349 Query: 1296 RRTKQVREDITVMQAPQFSRALHN--IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI 1353 + K + + V P+FS + ++ +G ++ LE ++ G+ ++WF + KP+ Sbjct: 1350 -KKKPITD---VGTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPV 1403 Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQ 1413 K + R Y D +L ++ P+D+ YTC+ATN+ G + + + A L+ E + Sbjct: 1404 KPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISA---LMPEGE 1460 Query: 1414 HPSGLEKI---QYLEDTS 1428 P +E + + +ED+S Sbjct: 1461 APKYVEPLKSDEIVEDSS 1478 Score = 58.4 bits (135), Expect = 1e-07 Identities = 73/332 (21%), Positives = 132/332 (39%), Gaps = 26/332 (7%) Query: 61 ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120 IT E + P F + K + + E + G P P ++W + + E ++ + Sbjct: 1151 ITIVEKPEGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITT 1210 Query: 121 RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC-SVYIQPEGXXXXXXXXXXXXXY 179 ++ +T +++ + + DEGEY C A N +G+A + + E Sbjct: 1211 VFDGETCVLNITVSCLD--DEGEYKCLAMNDFGKAATVAELLVNEALVKPKFIETTHDTE 1268 Query: 180 RHVSETV--EHKAYGTQGYTTEQSRQTQKVAYT-----NGTDHSST---DDFK-VDTFEY 228 E+V K G+ + + V+ T N + +ST +D K +D Y Sbjct: 1269 IITGESVWFRVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNY 1328 Query: 229 RLLREVSFRESIT--KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQ 286 + + E +T K V E I+ D P P + + P K+ +G D + Sbjct: 1329 KCIISNDAGEDMTVSKLTVIEKKKPIT---DVGTPPEFSPHVGEGPL--KISDGGDLTLE 1383 Query: 287 VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC 346 V+++G P+P + WFK+ + + S K + + +L + D+ YT A N +G Sbjct: 1384 VKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGT 1443 Query: 347 I-----VTSGYLAVESPTESYVQDQRSQYITD 373 V L E YV+ +S I + Sbjct: 1444 TTRNINVDISALMPEGEAPKYVEPLKSDEIVE 1475 Score = 58.4 bits (135), Expect = 1e-07 Identities = 56/226 (24%), Positives = 94/226 (41%), Gaps = 11/226 (4%) Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI--LTVYG 1911 T+ +EG ++ R+ P+P VEW+ N ++L ++ +D ++ L + G Sbjct: 2214 TEANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEG 2271 Query: 1912 ---EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAV 1968 ED Y+ A+N G+ S +L V SK +Q ++A ++ L + Sbjct: 2272 CAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVPEE 2331 Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK- 2027 + S + P F + +KN EV EG + + V +P+ ++WY + RF Sbjct: 2332 EAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRFVH 2389 Query: 2028 -TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 L I DTG Y C A N V E + + V K Sbjct: 2390 IDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435 Score = 58.0 bits (134), Expect = 2e-07 Identities = 68/274 (24%), Positives = 108/274 (39%), Gaps = 41/274 (14%) Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 + L + +D GTY C ATNK G V +E +D P+ + + IE + + Sbjct: 830 LTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQVNMEGIDTG----PQIQEYSKEIE-VVE 884 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G S EC +D +I WY + P+ S R +T D G L I D EY Sbjct: 885 GSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEYR 942 Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPK 3283 C G T + V L P + ++ LE + + P Sbjct: 943 CDIATDRG--VVSMTTELIVEEAV----LMPVIIQPLKSLEIKEENAARFDVRVRGSPQP 996 Query: 3284 FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343 + +D G+ R + +DD D + + Y+ +VI D Sbjct: 997 LVEWFKD------GRQLQDLGRFMIIDDVDDQDKELYS-----------------LVIED 1033 Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377 ++ E++GEYECVA N+ G+ ++ A L+ +K Sbjct: 1034 VI---PEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 58.0 bits (134), Expect = 2e-07 Identities = 102/437 (23%), Positives = 155/437 (35%), Gaps = 83/437 (18%) Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360 SL I+ C P+D YSV A+N G TS KG ++ S Sbjct: 1846 SLVIEGCAPDDDAVYSVVAMNEAGKDTS--------KGKLLVHS---------------- 1881 Query: 2361 PFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE 2420 RP+ +P P T+ L + + ++E + G+ + V W ++ + Sbjct: 1882 ---RPKQEQPTEPAGPRITKELVDAE-VEETTPVTLVAEFVSEGETS--VTWTKDAHRVV 1935 Query: 2421 DSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQH 2480 +R+T D ++ IS +DEG+Y C N +G+ ++ E Sbjct: 1936 ADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEA-- 1993 Query: 2481 PEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSL 2540 EP R F P+ Q EL EG + V G + Sbjct: 1994 -------------------EPPR-FVTPLKDQ------ELEEGSTV--DMLVETDGTSPI 2025 Query: 2541 RFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYM-CKAINRAGXXXXXXXXX 2599 +W+ + EL R T D T+ I+ V D +Y A N AG Sbjct: 2026 HIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVI 2085 Query: 2600 XXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQH 2659 +++KEAA E VD V API L ++EG Sbjct: 2086 -------------------VEVKEAAEVTPVEEVVDAAVP-APIIIKPLNDEIDVLEGDS 2125 Query: 2660 VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKA 2719 V LE + P+ ++ W+K+ L R+ D TL I S DD Y C Sbjct: 2126 VRLECVISG--GPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVV 2183 Query: 2720 TNLLGEAVSTASIKIED 2736 TN+ G + +E+ Sbjct: 2184 TNIAGSVDVKTELIVEE 2200 Score = 57.6 bits (133), Expect = 2e-07 Identities = 72/282 (25%), Positives = 117/282 (41%), Gaps = 48/282 (17%) Query: 1401 RVIAKKDLILESQHPS--GLEKIQYLEDTSRYKKTDIID-ESVTIKPRFVTRPKSIENVI 1457 RV + LI++S PS G K +T ++ E + P+ K IE V+ Sbjct: 825 RVDDRLTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQVNMEGIDTGPQIQEYSKEIE-VV 883 Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517 EG V EC+ D+ ++ W+K+ P+ RF A D+G+ Sbjct: 884 EGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFET---------------AFDNGLC 926 Query: 1518 TCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577 + R ++V DE R + +V T T+++ E Sbjct: 927 SLRIHDIVIDDEAEYRCDIATDRGVVSMT--------------------TELIVEEAVLM 966 Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-----TETNNF 1632 P+ LK++EIKE A F+ R + S L VEW+ + + L+ RF + + Sbjct: 967 PVIIQPLKSLEIKEENAARFDVR-VRGSPQPL-VEWFKDGRQLQDLGRFMIIDDVDDQDK 1024 Query: 1633 GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674 +L I +PED+G Y C A+N G+A ++ V +K S Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKIS 1066 Score = 57.2 bits (132), Expect = 3e-07 Identities = 63/288 (21%), Positives = 112/288 (38%), Gaps = 36/288 (12%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F D + ++ F + G P V+W + + R + L Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKY--EGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTL 1315 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830 ++ V P D G Y C N+ GE +T S L V ++K + + D Sbjct: 1316 IIEDVKPIDKGNYKCIISNDAGEDMTVSKLTV---------------IEKKKPITD---- 1356 Query: 1831 QRREDVEVAVNQAPRFITQLN-GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889 V P F + GP K+S+G E +I P P ++W+ + K ++ Sbjct: 1357 ---------VGTPPEFSPHVGEGPLKISDGGDLTLEVKITGEPKPE--IQWFKDDKPVKP 1405 Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949 + R +L I+ +D+ +YTCKA N G +I +++ + ++ Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGEAPKYV 1465 Query: 1950 SALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHL 1997 L+ + +ED S + V+ + + Q+ K +N V E VH+ Sbjct: 1466 EPLKSDEIVEDSS-FTMNVKFTGTPIPEVQWFK--ENKPVREDDRVHI 1510 Score = 56.4 bits (130), Expect = 5e-07 Identities = 61/266 (22%), Positives = 107/266 (40%), Gaps = 32/266 (12%) Query: 1566 RTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNN-KPLKSGS 1624 +T+++ E P+ LK+ E EG+ F+ R+ + L + K L Sbjct: 1775 KTELIVEEGISLPVIKEGLKDTEANEGEIVRFDIRVAGKPEPWLNGSRMTSLWKILFIII 1834 Query: 1625 RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGA 1684 + + +L I C P+D Y+ A+N G+ + G +VHS+ E E A Sbjct: 1835 DDVDDKDKELFSLVIEGCAPDDDAVYSVVAMNEAGKDTSKGKLLVHSRPK--QEQPTEPA 1892 Query: 1685 LPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRV 1744 PR+ T + D V E A + G+ V Sbjct: 1893 GPRI-------------------------TKELVDAEVEETTPVTLVAEFVSEGETS--V 1925 Query: 1745 EWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804 W ++ + A NR+T D L + + +D G YTC N++G+ TS+ + V+ Sbjct: 1926 TWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEE 1985 Query: 1805 KASLQLESQHESALQ--KIQQLEDSS 1828 +++ E++ + K Q+LE+ S Sbjct: 1986 LEAVESEAEPPRFVTPLKDQELEEGS 2011 Score = 56.0 bits (129), Expect = 7e-07 Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 8/109 (7%) Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471 + EE PV PL ++E ++E A F+ R+ + P VEW+ +G+ L+ RF Sbjct: 959 IVEEAVLMPVIIQPLKSLE-IKEENAARFDVRVRGSPQP--LVEWFKDGRQLQDLGRFMI 1015 Query: 3472 FCDFG-----FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 D L I PED+GEY C A N G+A +TA+++V K Sbjct: 1016 IDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 56.0 bits (129), Expect = 7e-07 Identities = 37/108 (34%), Positives = 52/108 (48%), Gaps = 8/108 (7%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E+ P P+K + IKE A F+ R+ G VEW KDGR ++ R Sbjct: 960 VEEAVLMPVIIQPLKS-LEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMII 1016 Query: 962 FNFG-----YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 + +L I+ V DAG Y C A N G+AT++A L ++TK Sbjct: 1017 DDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 56.0 bits (129), Expect = 7e-07 Identities = 89/390 (22%), Positives = 138/390 (35%), Gaps = 63/390 (16%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 KP+F + + E+ G V PT V+WY V RF + Sbjct: 1257 KPKFIETTHDTEIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRFLINTEEDTST 1314 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096 L I D G Y C +N GE +T S + V E+ Sbjct: 1315 LIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTV------------------------IEK 1350 Query: 2097 PKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156 KPI + G P F + LK D V+ +P I WF + + ++ Sbjct: 1351 KKPITDV--GTPPEFSPHVGE-GPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQ 1407 Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNG 2216 + R + +L I+ +D+ Y CKATNK G T T RNI +D Sbjct: 1408 KIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG----TTT------RNINVD------ 1451 Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276 I L +G + P++V L+ V + + F V+ P + Sbjct: 1452 ---ISALMPEGEA------------PKYVEPLKSDEIV---EDSSFTMNVKFTGTPIPEV 1493 Query: 2277 EFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336 +++ K ++ R HI + +L I VP+D G Y + N G S + V Sbjct: 1494 QWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMT 1553 Query: 2337 KGSIISESQRPEGLEKIRELESAEPFKRPE 2366 E P+ + E P ++P+ Sbjct: 1554 VSEAEDEGIIPKVTPTPGKTEITIPGQKPK 1583 Score = 55.6 bits (128), Expect = 9e-07 Identities = 80/360 (22%), Positives = 139/360 (38%), Gaps = 70/360 (19%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P F +PL+ ++ + E Q +C + G P ++ W + ++++ RIT D Sbjct: 1162 PEFIKPLKVLE-VFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDRITTVFDGETCV 1218 Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495 + I+ +DEG Y C A N G+ E E + K + +E H+ Sbjct: 1219 LNITVSCLDDEGEYKCLAMNDFGKAATVA------------ELLVNEALVKPKFIETTHD 1266 Query: 2496 RRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555 T+++TG S +W RV G P+ +WY + Sbjct: 1267 ---------------TEIITGES-VW--------FRVKYEGSPTPDVDWYHEDTLVSDTG 1302 Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPES 2615 RF + TL I V D G Y C N AG Sbjct: 1303 RFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAG------------------------- 1337 Query: 2616 WEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHL-KSYDKLVEGQHVYLEAQVEPRTDPNL 2674 E + + + + + + D G P F+ H+ + K+ +G + LE ++ +P Sbjct: 1338 -EDMTVSKLTVIEKKKPITDVGT--PPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKP 1392 Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +I+WFK+ + +++ + + +L+I DD+ YTCKATN G ++ I Sbjct: 1393 EIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDI 1452 Score = 55.2 bits (127), Expect = 1e-06 Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 8/111 (7%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E I E+ P I+PL+ L E++E A F+ ++ P VEW+KDGR + R Sbjct: 957 ELIVEEAVLMPVIIQPLKSL-EIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRF 1013 Query: 820 TSIFNFG-----YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 I + SL I + EDAG Y AVN+ G+A STA+++V + Sbjct: 1014 MIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 54.4 bits (125), Expect = 2e-06 Identities = 54/220 (24%), Positives = 93/220 (42%), Gaps = 34/220 (15%) Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101 KP+F+ T +I+ G+S F RV+ + T V+WY ++ R + Sbjct: 1257 KPKFIETTHDT-EIITGESVWF--RVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTS 1313 Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161 L I V+ D G Y + N AGE + +TV IE+ K Sbjct: 1314 TLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTV---------------------IEKKK 1352 Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPP-PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSV 1220 P+ + + P F + P +S+G ++ LE ++ G+P ++WF + + V Sbjct: 1353 ---PITDV----GTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPV 1403 Query: 1221 TVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260 + + Y +L I+ A+ DT +YT +A N G+ Sbjct: 1404 KPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGT 1443 Score = 54.0 bits (124), Expect = 3e-06 Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 8/110 (7%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P I PLKS+ E F+ R+ G P +EW K+G+ ++ RF I Sbjct: 967 PVIIQPLKSLEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDK 1024 Query: 697 DMLSLNIQD-----SGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQH 740 ++ SL I+D +GEY C AV+ G A + A L V T + +++T H Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKISELDKTPVH 1074 Score = 54.0 bits (124), Expect = 3e-06 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 2/92 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+FI PLK + E + E + G P +I WLK G ++ R T++F L Sbjct: 1162 PEFIKPLKVLEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDRITTVFDGETCVL 1219 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 ++ + D GEY C A++ G A T A L V Sbjct: 1220 NITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 53.2 bits (122), Expect = 5e-06 Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 9/123 (7%) Query: 909 PEFKTPIKD-QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 PEF + + + I +GG E ++ G+ ++W KD +PV+ S +I + Sbjct: 1361 PEFSPHVGEGPLKISDGGDLTLEVKIT--GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIH 1418 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI---QYLE 1024 +LTI + D YTC+A N G T + N+ I ++ E + P +E + + +E Sbjct: 1419 SLTIVGASPDDTAKYTCKATNKSGTTTRNINVDI---SALMPEGEAPKYVEPLKSDEIVE 1475 Query: 1025 DAS 1027 D+S Sbjct: 1476 DSS 1478 Score = 52.8 bits (121), Expect = 7e-06 Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 3/101 (2%) Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 +E+ P+FI+PL+ L E+ E + E +T +P ++ W K G + RIT+ Sbjct: 1154 VEKPEGAAPEFIKPLKVL-EVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITT 1210 Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 +F+ LNI +D G Y A+N G+A + A + V Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 52.8 bits (121), Expect = 7e-06 Identities = 65/289 (22%), Positives = 109/289 (37%), Gaps = 34/289 (11%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P+F H+ E + G +V + + G T V+W+ + RF E D L Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTL 1315 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRY 1430 + V P D G Y C +N GE +T K ++E + P Sbjct: 1316 IIEDVKPIDKGNYKCIISNDAGEDMT-------VSKLTVIEKKKPI-------------- 1354 Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490 TD+ P P I +G + E K+ + +++WFK+ +PV Sbjct: 1355 --TDV-GTPPEFSPHVGEGPLKIS---DGGDLTLEVKI--TGEPKPEIQWFKDDKPVKPS 1406 Query: 1491 HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550 + R + +L I+ +D+ YTC+A N GT + + + + + Sbjct: 1407 QKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGEAPKYVE 1466 Query: 1551 GLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599 L+ +++ED S T V T P +N ++E R H R Sbjct: 1467 PLKSDEIVEDSS---FTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIR 1512 Score = 52.8 bits (121), Expect = 7e-06 Identities = 58/252 (23%), Positives = 100/252 (39%), Gaps = 13/252 (5%) Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228 I E S PV + L + +EG + + R+ G P VEWF N + +F Sbjct: 2197 IVEEGISLPVIKEGLKDTE-ANEGDVVRFDIRVA--GKPEPVVEWFKNDELLDDSGKFII 2253 Query: 1229 YYDFG-----FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283 D +L I D Y+V A+N G + + V + + Q + Sbjct: 2254 IDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADA 2313 Query: 1284 AIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMR 1343 A ++ L + + +AP F + NIE +EG + + V + + Sbjct: 2314 ATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPS-- 2371 Query: 1344 VEWFCNGKPIKTGHRF--RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401 ++W+ + I RF A + + L + + D+G YTC A N + E +T A+ Sbjct: 2372 IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDE-ITCEAVL 2430 Query: 1402 VIAKKDLILESQ 1413 + K++ E Q Sbjct: 2431 TVKPKEIAPEFQ 2442 Score = 52.4 bits (120), Expect = 9e-06 Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 7/95 (7%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG---- 3885 P I +KS ++E RF+ RV + P+ +EW+++G+ L R+ + D+ Sbjct: 967 PVIIQPLKSLEIKEENAARFDVRV--RGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDK 1024 Query: 3886 -FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 SL I V ED+GEY C AVN+ G+ + AT+ Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATL 1059 Score = 52.0 bits (119), Expect = 1e-05 Identities = 58/243 (23%), Positives = 97/243 (39%), Gaps = 32/243 (13%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E++E + ++ P+F+ PL+D EL+EG + T + P + ++W+KD + + R Sbjct: 1987 EAVESE-AEPPRFVTPLKDQ-ELEEGSTVDMLVE-TDGTSP-IHIKWFKDNKELVPDERH 2042 Query: 820 TSIFNFGYVSLNIMHLRAED-AGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQR 878 T + ++ I + ED A Y V A N GEA++ A + V + A++ E+ Sbjct: 2043 TFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKE--AAEVTPVEE- 2099 Query: 879 RYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGD 938 V + P P+ D+I + EG E + G Sbjct: 2100 ----------------------VVDAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS--GG 2135 Query: 939 STLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSAN 998 +V W KD +E RI + L I+S + D Y C N G Sbjct: 2136 PDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTE 2195 Query: 999 LTI 1001 L + Sbjct: 2196 LIV 2198 Score = 52.0 bits (119), Expect = 1e-05 Identities = 61/235 (25%), Positives = 91/235 (38%), Gaps = 25/235 (10%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 + P F P+KD + E + + G + ++W ++ + R T D Sbjct: 1994 EPPRFVTPLKDQELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKH 2051 Query: 1769 ALNMKYVNPEDSGTY-TCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827 + + V ED Y A N GEAVT + + V+ K E+A ++ +E Sbjct: 2052 TMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK---------EAA--EVTPVE-- 2098 Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887 E V+ AV AP I LN + EG S EC I PD +V WY + +L Sbjct: 2099 ------EVVDAAV-PAPIIIKPLNDEIDVLEGDSVRLECVISGGPD--AQVLWYKDDYLL 2149 Query: 1888 QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942 + R D L I + +D EY C N G L V+ S+ Sbjct: 2150 EEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISL 2204 Score = 51.6 bits (118), Expect = 2e-05 Identities = 41/153 (26%), Positives = 71/153 (46%), Gaps = 12/153 (7%) Query: 2197 CTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256 C+L++ +I++D + + +T + VEE + P + L+ + + E Sbjct: 926 CSLRI---HDIVIDDEAEYRCDIATDRGVVSMTTELIVEEAVLMPV-IIQPLK-SLEIKE 980 Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG-----YVSLDIQHCVPED 2311 A F+ +V P +E++ +G+ LQ RF I D SL I+ +PED Sbjct: 981 ENAARFDVRVRG--SPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPED 1038 Query: 2312 AGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344 AGEY A+N G TS ++ V K S + ++ Sbjct: 1039 AGEYECVAVNEAGKATSTATLQVLTKISELDKT 1071 Score = 51.6 bits (118), Expect = 2e-05 Identities = 53/217 (24%), Positives = 89/217 (41%), Gaps = 32/217 (14%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P+F +E + ++ G V F RV+ G PT +DW+H + R + Sbjct: 1258 PKF-IETTHDTEIITGESVWF--RVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTST 1314 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814 L I+ + D G Y C +N G T +K+T V+E + P I + Sbjct: 1315 LIIEDVKPIDKGNYKCIISNDAGEDMTVSKLT-------VIEKKKP-------ITD---- 1356 Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874 + P+ P V P ++ S+G V+ +PK I+W+++ K + Sbjct: 1357 -VGTPPEFSPHVGEGP----------LKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKP 1405 Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 + R Y SL I+ +D+ +Y C+A N G Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG 1442 Score = 51.2 bits (117), Expect = 2e-05 Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 58 RQPIT-AGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECN 116 ++PIT G P E SP + E K + GG+ E K+ G P P + W + P+ Sbjct: 1351 KKPITDVGTPPEFSPHVGEGPLK---ISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQ 1407 Query: 117 KYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 K + Y + SL I P D +YTC A N+ G Sbjct: 1408 KIRVDYRDDIH--SLTIVGASPDDTAKYTCKATNKSG 1442 Score = 51.2 bits (117), Expect = 2e-05 Identities = 78/344 (22%), Positives = 123/344 (35%), Gaps = 59/344 (17%) Query: 1469 EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528 E V++ V W K+ V +R D L I +D G+YTC N +G Sbjct: 1916 EFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDT 1975 Query: 1529 EVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVE 1588 ST E +E+++ +E + + P T LK+ E Sbjct: 1976 ----------------STSAEVIVEELEAVESEA-------------EPPRFVTPLKDQE 2006 Query: 1589 IKEGQRAHFERRLIPVSDAT--LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPED 1646 ++EG ++ +D T + ++W+ +NK L R T T + + I ED Sbjct: 2007 LEEGSTVD----MLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLED 2062 Query: 1647 SGT-YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDE 1705 Y A N GEAVT IV K++ + E + Sbjct: 2063 EAMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTPVEEVV--------------------D 2102 Query: 1706 VITQAPVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764 AP+ P+ D I V E + E + G P +V W ++ +E R+ D Sbjct: 2103 AAVPAPIIIKPLNDEIDVLEGDSVRLEC--VISGGPDAQVLWYKDDYLLEEDERIMYDTD 2160 Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 L ++ +D Y C N G + L V+ SL Sbjct: 2161 GDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISL 2204 Score = 50.8 bits (116), Expect = 3e-05 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG--- 2165 PV + L SLE +KE + A F+ RV P ++WF +G++++ R+ D Sbjct: 967 PVIIQPLKSLE-IKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023 Query: 2166 --YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 +L I ED+G Y C A N+ G+A +T TL+V Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQV 1061 Score = 50.4 bits (115), Expect = 3e-05 Identities = 73/342 (21%), Positives = 130/342 (38%), Gaps = 40/342 (11%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P ++ W K+G + ++ L+I DDSG Y C T+ +G++ T S Sbjct: 203 PEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFS 262 Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791 + IE E P ++ L F+S K D Sbjct: 263 VDIE------SEGPAPKESEKRKLLKGEERPK------------FVSDSTVEEFKITDEG 304 Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTR-YKSTHDFSYVSLDITHTYEEDSGIYTCKA 2850 V+ + P ++EW ++K L R S D V L I DSG+Y C+ Sbjct: 305 ELRLTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQV 364 Query: 2851 TNSKGSATTSGSLRCTGD-----KNIYFD-TQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904 ++ G++T S + G+ K I D T+H + + ++ V++ + Sbjct: 365 SSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKR--IKHVKEPVPEEQVMPTKVKPV 422 Query: 2905 DTEYPKPEWIIPIAA----EHQLVEGQVLH-----LEGQV----EPKNDPDLKIEWYFNG 2951 +T+ KP I + A E +E + EG + + P +EW+ + Sbjct: 423 ETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQVTGKPQPSVEWFKDD 482 Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 + +T + G +L + + ++D G YT + N+ G Sbjct: 483 VPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAG 524 Score = 50.4 bits (115), Expect = 3e-05 Identities = 56/259 (21%), Positives = 100/259 (38%), Gaps = 43/259 (16%) Query: 3545 VDTLTPEAESGNPPEFTTTPSD--LILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT 3602 ++ P + G PPEF+ + L +S+ E ++ + ++WF + KP+ Sbjct: 1348 IEKKKPITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPVKP 1405 Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662 +++ L I G D YTCKATN+ G T + + + ++ E + P Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDI---SALMPEGEAP 1462 Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722 + ++ L K +EI +ED FT+ +K G P+ Sbjct: 1463 KY-------VEPL-----KSDEI-VEDSS-----FTMNVKFT-----GTPI--------- 1490 Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 + WF +P RVH + + L I D G Y +N +G A + Sbjct: 1491 ----PEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSE 1546 Query: 3783 AKITCSAKRDIVLESQLPQ 3801 A++ + E +P+ Sbjct: 1547 AELVVMTVSEAEDEGIIPK 1565 Score = 50.0 bits (114), Expect = 5e-05 Identities = 49/210 (23%), Positives = 87/210 (41%), Gaps = 21/210 (10%) Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102 DTG P+ K+I ++ EG E +G + I W+ + + S R T + Sbjct: 868 DTG--PQIQEYSKEI-EVVEGSSVTIECQ--SSGAEDARITWYKDDVPLGDSPRFETAFD 922 Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162 G+ L I D Y C G +S+ E + + P ++++E +K Sbjct: 923 NGLCSLRIHDIVIDDEAEYRCDIATDRGV--VSMTTELIVEEAVLMPVIIQPLKSLE-IK 979 Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--------FGFVVLDIAYT 3214 + +A F+ V P +EW+ +G+ ++ R + D + V+ D+ Sbjct: 980 EENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVI-- 1035 Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244 D+GEY C A N+ G+ + AT+ K Sbjct: 1036 -PEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 50.0 bits (114), Expect = 5e-05 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 7/92 (7%) Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFG-----FAALDILTV 1909 ++ E +A ++ R+ P P VEW+ +G+ LQ R+ +D +L I V Sbjct: 977 EIKEENAARFDVRVRGSPQP--LVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDV 1034 Query: 1910 YGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 ED+GEY C A+N G+A S+ L V +K S Sbjct: 1035 IPEDAGEYECVAVNEAGKATSTATLQVLTKIS 1066 Score = 50.0 bits (114), Expect = 5e-05 Identities = 53/239 (22%), Positives = 97/239 (40%), Gaps = 43/239 (17%) Query: 3687 IEDEKP-----NPPRFTVEIKDN-IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740 IE +KP PP F+ + + + + +GG + + ++ G+P I WF + +P Sbjct: 1348 IEKKKPITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPVKP 1405 Query: 3741 GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800 ++ +L I D +YTC+ATNK S TTT I ++ + + +P Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNK--SGTTTRNI------NVDISALMP 1457 Query: 3801 QGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPK 3860 +G +APK ++ +KS + E F V+ P Sbjct: 1458 EG---------------EAPK----------YVEPLKSDEIVEDSS--FTMNVKFTGTPI 1490 Query: 3861 LRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 ++W++ K + R + + +L I +D G Y N FG+ ++A + Sbjct: 1491 PEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAEL 1549 Score = 50.0 bits (114), Expect = 5e-05 Identities = 86/362 (23%), Positives = 131/362 (36%), Gaps = 54/362 (14%) Query: 1964 YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023 + R Q+ P+ K + +AEV E PV L A V++ V W + V Sbjct: 1880 HSRPKQEQPTEPAGPRITKELVDAEVEETTPVTLVAEF--VSEGETSVTWTKDAHRVVAD 1937 Query: 2024 HRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQ 2083 +R D L I + +D G Y C N +G+ T++ V V Sbjct: 1938 NRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIV-------------- 1983 Query: 2084 RLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTI 2143 +ELE E E +P P F+T L E L+EG + VE + I Sbjct: 1984 -----EELEAVE-----SEAEP---PRFVTPLKDQE-LEEGSTV--DMLVETDGTSPIHI 2027 Query: 2144 DWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT-YMCKATNKLGEAVNTCTLKVA 2202 WF + +++ R+ T D + I ED Y A N GEAV Sbjct: 2028 KWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDA----- 2082 Query: 2203 GHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHF 2262 +I++ + EA + EV + + P + L V EG + Sbjct: 2083 ---EVIVEVK-----------EAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRL 2128 Query: 2263 ECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINA 2322 EC + P+ ++ +Y + L+ R D +L IQ +D EY N Sbjct: 2129 ECVIS--GGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNI 2186 Query: 2323 LG 2324 G Sbjct: 2187 AG 2188 Score = 50.0 bits (114), Expect = 5e-05 Identities = 58/249 (23%), Positives = 93/249 (37%), Gaps = 24/249 (9%) Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY-----KSTHDFSYVSLD 2834 L + EGD + F+ V +P +EWF N++ L ++ D SL Sbjct: 2211 LKDTEANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLV 2268 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894 I ED +Y+ A N G ++ G L Q A +E E Sbjct: 2269 IEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPE---QEAPAQADAATPILEPLVET- 2324 Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKNDPDLKIEWYFN 2950 P VP+ E PE P+ E +++EG+ + V+ P+ I+WY Sbjct: 2325 -----IPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVD--GVPEPSIDWYRG 2377 Query: 2951 GKVLEQGSRFKLTSDF--GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008 +++ RF TL + + D+G YTC A N E + + K+ Sbjct: 2378 EELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPKEI 2437 Query: 3009 LIERTQHPK 3017 E + P+ Sbjct: 2438 APEFQKEPE 2446 Score = 50.0 bits (114), Expect = 5e-05 Identities = 50/234 (21%), Positives = 93/234 (39%), Gaps = 15/234 (6%) Query: 1057 EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG-----YVALDIASVRAE 1111 EG F+ RV + + VEW+ N + + + + D +L I E Sbjct: 2218 EGDVVRFDIRVAGKPE--PVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPE 2275 Query: 1112 DSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEE 1171 D VY+VVA N AG+ + V ++ + + + E+ P + Sbjct: 2276 DDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVPEEEAAS 2335 Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231 PVF++ + N V EG+ + ++ + +P+ ++W+ + RF + D Sbjct: 2336 PETKAPVFIETMKN-IEVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRF-VHID 2391 Query: 1232 F---GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282 L I + DTG+YT A N + A++ ++ +I + Q E Sbjct: 2392 AVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVL-TVKPKEIAPEFQKE 2444 Score = 49.6 bits (113), Expect = 6e-05 Identities = 68/291 (23%), Positives = 120/291 (41%), Gaps = 32/291 (10%) Query: 1796 TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQA--PRFITQLNGP 1853 TSSTL + SK+ + E + ++ +S E++E ++A PRF+T L Sbjct: 1947 TSSTLAI-SKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPLKDQ 2005 Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913 +L EG + + +E + ++W+ + K L R+ + D + I V ED Sbjct: 2006 -ELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLED 2062 Query: 1914 SGEYTCKAINNL-GQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDS 1972 Y N+ G+AV+ + V+ KE+ + + ++ + D + Sbjct: 2063 EAMYYKVVAENVAGEAVTDAEVIVEVKEA--------AEVTPVEEVVDAA---------- 2104 Query: 1973 FVVEKPQFGKPIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031 V P KP+ + +V EG V LE ++ P +V WY + +++ R D Sbjct: 2105 --VPAPIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLLEEDERIMYDTD 2160 Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082 L I A +D Y C TN G + + V+ G+ L + E Sbjct: 2161 GDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVE--EGISLPVIKE 2209 Score = 49.6 bits (113), Expect = 6e-05 Identities = 58/230 (25%), Positives = 84/230 (36%), Gaps = 26/230 (11%) Query: 3683 EEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742 EE+ + + PPRF +KD ++ EG V D VE G + I WF + + Sbjct: 1984 EELEAVESEAEPPRFVTPLKDQ-ELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDE 2040 Query: 3743 RVHTLNDFGFIALDIDYIYARD-AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801 R D + I + D A Y A N G A T A++ K Sbjct: 2041 RHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK----------- 2089 Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861 ++ +E + DA PI+ P V E + VR EC + P Sbjct: 2090 --EAAEVTPVE--EVVDAAVPAPIIIKPLN-----DEIDVLEGDSVRLECVI--SGGPDA 2138 Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 ++ WY++ LL R D +L I +D EY C N G Sbjct: 2139 QVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188 Score = 49.2 bits (112), Expect = 8e-05 Identities = 35/148 (23%), Positives = 57/148 (38%), Gaps = 5/148 (3%) Query: 45 TRQMTTQVESSGDRQPITAGRP---GEPSPP-IFEQIFKNARFAQGGNAKFEGKLRGNPT 100 TR + +ES G + R GE P + + + + G + K+ G P Sbjct: 258 TRTFSVDIESEGPAPKESEKRKLLKGEERPKFVSDSTVEEFKITDEGELRLTVKVTGKPF 317 Query: 101 PVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVY 160 P V WT+ L E ++ + + G V L IK +G D G Y C + G + S Sbjct: 318 PEVEWTKDDKDLKEDDRVIIS-EQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTSTKSFD 376 Query: 161 IQPEGXXXXXXXXXXXXXYRHVSETVEH 188 + EG H+ + ++H Sbjct: 377 VTIEGERRKAKKLIEVDETEHLEKRIKH 404 Score = 49.2 bits (112), Expect = 8e-05 Identities = 38/137 (27%), Positives = 64/137 (46%), Gaps = 9/137 (6%) Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333 DIV D + E + + T+ + E+ +M P + L ++E E + R Sbjct: 932 DIVIDDEAEYRCDIATDRGVVSMTTELIVEEAVLM--PVIIQPLKSLEIKEENAARFDVR 989 Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS-----VYPEDSGVYTCQAT 1388 ++ G VEWF +G+ ++ RF + D +L S V PED+G Y C A Sbjct: 990 VR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAV 1047 Query: 1389 NQLGEAVTSCALRVIAK 1405 N+ G+A ++ L+V+ K Sbjct: 1048 NEAGKATSTATLQVLTK 1064 Score = 49.2 bits (112), Expect = 8e-05 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 7/92 (7%) Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG-----FIALDID 3758 ++++ E FD RV G P ++WF +GR R ++D +L I+ Sbjct: 975 SLEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIE 1032 Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 + DAGEY C A N+ G AT+TA + K Sbjct: 1033 DVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 49.2 bits (112), Expect = 8e-05 Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 6/128 (4%) Query: 1812 SQHESALQKIQQLEDSSRYQRRED---VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRI 1868 S ++ K DS + + D VE AP FI L ++ E Q EC + Sbjct: 1127 SPSDAGTYKCVTKNDSGTFTQMFDITIVEKPEGAAPEFIKPLK-VLEVFETQPVRLECSV 1185 Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928 P+P ++ W G V++ R T D L+I +D GEY C A+N+ G+A Sbjct: 1186 TGTPEP--QITWLKGGDVVKEDDRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKA 1243 Query: 1929 VSSIRLNV 1936 + L V Sbjct: 1244 ATVAELLV 1251 Score = 49.2 bits (112), Expect = 8e-05 Identities = 36/104 (34%), Positives = 48/104 (46%), Gaps = 6/104 (5%) Query: 3684 EITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 +ITI EKP P F +K ++V E PV +C V G P +I W G Sbjct: 1150 DITIV-EKPEGAAPEFIKPLKV-LEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKED 1205 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 R+ T+ D L+I D GEY C A N +G A T A++ Sbjct: 1206 DRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAEL 1249 Score = 49.2 bits (112), Expect = 8e-05 Identities = 52/223 (23%), Positives = 92/223 (41%), Gaps = 26/223 (11%) Query: 3954 TSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG 4013 ++EV + E + + + +PPRFVT ++ Q L E T + + G + ++WF + Sbjct: 1978 SAEVIVEELEAVE-SEAEPPRFVTPLKDQ-ELEEGSTV--DMLVETDGTSPIHIKWFKDN 2033 Query: 4014 KPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVY 4073 K L+ R T D M V ED Y +V Sbjct: 2034 KELVPDERHTFTKDGNKHTMTISPVTLEDEAMYY----------------------KVVA 2071 Query: 4074 DSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCR 4133 ++ + + E I E++ + +VTP + V ++ P + L D + V EG+ R C Sbjct: 2072 ENVAGEAVTDAEVIVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRLECV 2131 Query: 4134 VTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYD 4176 ++G P +V+W + + R DG H I ++ + D Sbjct: 2132 ISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELD 2174 Score = 49.2 bits (112), Expect = 8e-05 Identities = 80/316 (25%), Positives = 120/316 (37%), Gaps = 33/316 (10%) Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467 K + EE PV L + E EG+ F+ R+ +P VEW+ N + L Sbjct: 2193 KTELIVEEGISLPVIKEGLKDTE-ANEGDVVRFDIRVAGKPEP--VVEWFKNDELLDDSG 2249 Query: 3468 RFRTFCDFG-----FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILES 3522 +F D L I PED Y A N G+ + + V K E Sbjct: 2250 KFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKP----EQ 2305 Query: 3523 QLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP----PEFTTTPSDLILSENSSAHFE 3578 + P + LE T+ + PE E+ +P P F T ++ + E A F+ Sbjct: 2306 EAPAQADAATP---ILEPLVETIPEV-PEEEAASPETKAPVFIETMKNIEVMEGEEARFD 2361 Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI--LEIGGVYQRDAGLYTCKATN 3636 + V + S ++W+ + + R I+ I L I D G YTC A N Sbjct: 2362 VHVDGVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAAN 2419 Query: 3637 RHGEATVSCKLQVKGRQ---GIILEPQLPSHFKSGTESIQKLEETLHKREEITIE---DE 3690 E T L VK ++ EP+ S F T L+ T+ + +E D+ Sbjct: 2420 DVDEITCEAVLTVKPKEIAPEFQKEPE-KSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDD 2478 Query: 3691 KP--NPPRFTVEIKDN 3704 KP R V+ KD+ Sbjct: 2479 KPVKGTRRLEVKAKDD 2494 Score = 49.2 bits (112), Expect = 8e-05 Identities = 25/94 (26%), Positives = 43/94 (45%) Query: 68 EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127 E P+F + KN +G A+F+ + G P P + W R + + + ++ + Sbjct: 2337 ETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPSIDWYRGEELIPDEGRFVHIDAVKEE 2396 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161 +L+I+ GD G+YTC A N E C + Sbjct: 2397 IFTLVIENTKLGDTGKYTCIAANDVDEITCEAVL 2430 Score = 48.8 bits (111), Expect = 1e-04 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 5/125 (4%) Query: 45 TRQMTTQVESSGDRQPITAG---RPGEPSPP-IFEQIFKNARFAQGGNAKFEGKLRGNPT 100 TR + +ES G + R GE P + + + + G + K+ G P Sbjct: 632 TRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGKPF 691 Query: 101 PVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVY 160 P V WT+ L E N+ + + G V L IK +G D G Y C + G + S Sbjct: 692 PEVEWTKDDKDLKEDNRVIIS-EQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFD 750 Query: 161 IQPEG 165 + EG Sbjct: 751 VTIEG 755 Score = 48.8 bits (111), Expect = 1e-04 Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 11/151 (7%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P++ +P+K+ E+ E + T P V+W+ +PV++ R + Sbjct: 1460 EAPKYVEPLKSDEIVEDSSFTMNVKFT--GTPIPEVQWFKENKPVREDDRVHIIRESDSS 1517 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 L I +D G+Y +N G+AV+ + + V S + DE + K+ Sbjct: 1518 TLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVS----EAEDEGIIPKVT-----P 1568 Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDR 2126 P E PGQ+P F ++ LK+ +R Sbjct: 1569 TPGKTEITIPGQKPKFGPVEVDIKGLKDKER 1599 Score = 48.8 bits (111), Expect = 1e-04 Identities = 57/226 (25%), Positives = 92/226 (40%), Gaps = 25/226 (11%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 + P F T LK + L EG V + + + T P + I+WFK+ L R T D Sbjct: 1994 EPPRFVTPLKDQE-LEEGSTVDMLVETDG-TSP-IHIKWFKDNKELVPDERHTFTKDGNK 2050 Query: 2700 VTLSINSLRNDDSGIY-TCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXX 2758 T++I+ + +D +Y A N+ GEAV+ A + +E + E+ ++ + Sbjct: 2051 HTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK-----EAAEVTPVEEV----- 2100 Query: 2759 XXXXXXXXXXXXXXXXVFISHLNN-IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLP 2817 + I LN+ I EGD++ EC + S P ++ W+ ++ L Sbjct: 2101 --------VDAAVPAPIIIKPLNDEIDVLEGDSVRLECVI--SGGPDAQVLWYKDDYLLE 2150 Query: 2818 SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 R D +L I +D Y C TN GS L Sbjct: 2151 EDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL 2196 Score = 48.4 bits (110), Expect = 1e-04 Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 2/86 (2%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885 + T P+ K V E V EC+ ED RI WY++ L R+ T +D G Sbjct: 867 IDTGPQIQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNG 924 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFG 3911 SL I + +D EY C D G Sbjct: 925 LCSLRIHDIVIDDEAEYRCDIATDRG 950 Score = 48.4 bits (110), Expect = 1e-04 Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 9/111 (8%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG--- 1099 P + PLK +I E +A F+ RV VEW+ +G+Q+ R D Sbjct: 967 PVIIQPLKSL-EIKEENAARFDVRVRGSPQ--PLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023 Query: 1100 --YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR-SSIDTSSIH 1147 +L I V ED+G Y VA N AG+A +A++ V T+ S +D + +H Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKISELDKTPVH 1074 Score = 48.4 bits (110), Expect = 1e-04 Identities = 63/260 (24%), Positives = 101/260 (38%), Gaps = 19/260 (7%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E I E+ P L+D E EG F+ ++ +P VEW+K+ + S + Sbjct: 2195 ELIVEEGISLPVIKEGLKDT-EANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGKF 2251 Query: 820 TSIFNFG-----YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874 I + SL I ED Y+V A+N+ G+ S + V ++ A Sbjct: 2252 IIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEA---- 2307 Query: 875 PEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLE 934 P Q PE T+ P F +K+ I + EG A F+ ++ Sbjct: 2308 PAQADAATPILEPLVETIPEVPEEEAASPE-TKAPVFIETMKN-IEVMEGEEARFDVHVD 2365 Query: 935 PIGDSTLRVEWLKDGRPVEASSRITTF--FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ 992 + + + ++W + + R L I++ + D G YTC A N + + Sbjct: 2366 GVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDE 2423 Query: 993 ATTSANLTIVTKKDIIAESQ 1012 T A LT V K+I E Q Sbjct: 2424 ITCEAVLT-VKPKEIAPEFQ 2442 Score = 48.0 bits (109), Expect = 2e-04 Identities = 90/431 (20%), Positives = 167/431 (38%), Gaps = 55/431 (12%) Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 V+ P+ ++ W +GK +++ +L L + + DSG Y C + G+ Sbjct: 571 VKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGK 630 Query: 2995 AFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVF 3054 + + +V SK + ++ K +G E+ + + DS +E F Sbjct: 631 STRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEE------------------F 672 Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR-IRTVYAFGMVVLEILGT 3113 K I D EG++ ++ TG +EW + K ++ +R I + G+VVL I Sbjct: 673 K-ITD--EGEL---RLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDV 726 Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLECV-DKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172 DSG Y C+ T+ G + S + ++ K +K ++D A FE T Sbjct: 727 GAHDSGVYKCKVTSDVGTSTKSFDVTIEGERRKAKKLIEVDDTVAPHFVEDTSIAPFELT 786 Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 D D+++ G+P + K D F + + D + ++ + + Sbjct: 787 ----DSGDVRLSVRVAGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIVKSPSPSDQ 842 Query: 3233 DFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVT 3292 + T KGG + Q + +E + Q I + Sbjct: 843 GTYKCTAT--NKGGTVTRTFQVN-------MEGIDTGPQ-------------IQEYSKEI 880 Query: 3293 KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENS 3352 ++VEG S E + + D ++ W+ + L R+ T D G+ L I ++ Sbjct: 881 EVVEGSSVTIECQSSGAE--DARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDE 938 Query: 3353 GEYEC-VATNK 3362 EY C +AT++ Sbjct: 939 AEYRCDIATDR 949 Score = 48.0 bits (109), Expect = 2e-04 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Query: 1304 DITVMQ-----APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR 1358 DIT+++ AP+F + L +E E V LEC + G ++ W G +K R Sbjct: 1150 DITIVEKPEGAAPEFIKPLKVLEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDR 1207 Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 ++ + L++ +D G Y C A N G+A T L V Sbjct: 1208 ITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 48.0 bits (109), Expect = 2e-04 Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 3/102 (2%) Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159 I E+ G P F+ L LE + E EC V +P +T W G ++ R Sbjct: 1153 IVEKPEGAAPEFIKPLKVLE-VFETQPVRLECSVTGTPEPQIT--WLKGGDVVKEDDRIT 1209 Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 T D L+I + +D G Y C A N G+A L V Sbjct: 1210 TVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 48.0 bits (109), Expect = 2e-04 Identities = 56/241 (23%), Positives = 103/241 (42%), Gaps = 24/241 (9%) Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG-----FVSLD 3890 +K E + VRF+ RV K +P +EW++N +LL ++ + D+ SL Sbjct: 2211 LKDTEANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLV 2268 Query: 3891 ILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATI 3950 I ED Y A+N+ G+D +K + P + + P +++A T + + Sbjct: 2269 IEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKP----EQEAP---AQADAATPILEPL 2321 Query: 3951 KKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWF 4010 + EV E++ + K P F+ + ++E E +F+ + V +P+ ++W+ Sbjct: 2322 VETIPEV--PEEEAASPETKAPV-FI-ETMKNIEVMEGEEARFDVHVDGVPEPS--IDWY 2375 Query: 4011 FNGKPLLHKNRFTPI--YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068 + + + RF I + D+G+Y C A N +DE T K Sbjct: 2376 RGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAAN--DVDEITCEAVLTVK 2433 Query: 4069 P 4069 P Sbjct: 2434 P 2434 Score = 47.6 bits (108), Expect = 2e-04 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696 G+ P + K + +VEG V +E Q D +I W+K+ V L R ++ FD Sbjct: 866 GIDTGPQIQEYSKEIE-VVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFD 922 Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 GL +L I+ + DD Y C G T + +E+ Sbjct: 923 NGLCSLRIHDIVIDDEAEYRCDIATDRGVVSMTTELIVEE 962 Score = 47.2 bits (107), Expect = 3e-04 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 5/114 (4%) Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356 RT QV + + PQ IE VEG++V +EC Q G + R+ W+ + P+ Sbjct: 858 RTFQVNME-GIDTGPQIQEYSKEIEVVEGSSVTIEC--QSSGAEDARITWYKDDVPLGDS 914 Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410 RF A++ +L + + +D Y C G V S +I ++ +++ Sbjct: 915 PRFETAFDNGLCSLRIHDIVIDDEAEYRCDIATDRG--VVSMTTELIVEEAVLM 966 Score = 47.2 bits (107), Expect = 3e-04 Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 PEF P+K + + E E + G ++ WLK G V+ RITT F+ Sbjct: 1162 PEFIKPLK-VLEVFETQPVRLECSVT--GTPEPQITWLKGGDVVKEDDRITTVFDGETCV 1218 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 L I + D G Y C A N G+A T A L + Sbjct: 1219 LNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 47.2 bits (107), Expect = 3e-04 Identities = 48/212 (22%), Positives = 85/212 (40%), Gaps = 38/212 (17%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669 +++W+ ++KP+K + +L I+ P+D+ YTC+A N G T I + Sbjct: 1393 EIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG-TTTRNINVD 1451 Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729 S EG P KY DE++ + FTM +K Sbjct: 1452 IS------ALMPEGEAP---------KYVEPLKSDEIVEDSS-FTMNVKF---------- 1485 Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789 G P V+W + P+ +R+ + + L + P+D G+Y N Sbjct: 1486 -------TGTPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSN 1538 Query: 1790 ELGEAVTSSTLFVQSKASLQLESQHESALQKI 1821 G+AV+ + L V + + E++ E + K+ Sbjct: 1539 PFGKAVSEAELVVMTVS----EAEDEGIIPKV 1566 Score = 47.2 bits (107), Expect = 3e-04 Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 6/110 (5%) Query: 1298 TKQVREDITVM----QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI 1353 T+ + DI+ + +AP++ L + E VE ++ + + G V+WF KP+ Sbjct: 1445 TRNINVDISALMPEGEAPKYVEPLKSDEIVEDSSFTMNVKF--TGTPIPEVQWFKENKPV 1502 Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 + R E D L + P+D G Y +N G+AV+ L V+ Sbjct: 1503 REDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVM 1552 Score = 47.2 bits (107), Expect = 3e-04 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 3/118 (2%) Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468 D S +G+AP + PL + E + E++ F + T P +V+W+ K ++ R Sbjct: 1451 DISALMPEGEAPKYVEPLKSDEIV---EDSSFTMNVKFTGTPIPEVQWFKENKPVREDDR 1507 Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPK 3526 + L I+ T P+D G Y N +G+AV+ A + V E +PK Sbjct: 1508 VHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEAEDEGIIPK 1565 Score = 47.2 bits (107), Expect = 3e-04 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433 + P +PL + ++ EG +A +C + G P V W++++ L+E+ R++ D Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLEC--VISGGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458 ++ I +DE Y C +N+ G Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAG 1770 Score = 47.2 bits (107), Expect = 3e-04 Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 3/128 (2%) Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750 +P PR T E+ D +V E PV G+ + + W + +RV D Sbjct: 1890 EPAGPRITKELVD-AEVEETTPVTLVAEFVSEGETS--VTWTKDAHRVVADNRVTIKTDE 1946 Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810 L I D G YTC NK G +T+A++ + E++ P+ ++ K +E Sbjct: 1947 TSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPLKDQE 2006 Query: 3811 LERGRISD 3818 LE G D Sbjct: 2007 LEEGSTVD 2014 Score = 47.2 bits (107), Expect = 3e-04 Identities = 54/242 (22%), Positives = 91/242 (37%), Gaps = 15/242 (6%) Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690 E+ V+ G+ P+ LK + EG V + +V + +P +EWFKN L + Sbjct: 2195 ELIVEEGIS-LPVIKEGLKDTEAN-EGDVVRFDIRVAGKPEP--VVEWFKNDELLDDSGK 2250 Query: 2691 LKSTFDFG-----LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESL 2745 D L +L I +D +Y+ A N G+ S + + + + Sbjct: 2251 FIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQ 2310 Query: 2746 HPDSLDRIGALXXXXXXXXXXXXXX--XXXXVFISHLNNIVCKEGDNIHFECNVEPSRDP 2803 + + L VFI + NI EG+ F+ +V+ +P Sbjct: 2311 ADAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEP 2370 Query: 2804 TLKIEWFFNNKPLPSGTRYKSTHDF--SYVSLDITHTYEEDSGIYTCKATNSKGSATTSG 2861 + I+W+ + +P R+ +L I +T D+G YTC A N T Sbjct: 2371 S--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEA 2428 Query: 2862 SL 2863 L Sbjct: 2429 VL 2430 Score = 46.8 bits (106), Expect = 4e-04 Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 7/131 (5%) Query: 2608 DQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIF--TTHLKSYDKLVEGQHVYLEAQ 2665 ++ + P + ++ K ++ E VD +++ P F + +K ++ EG + + AQ Sbjct: 411 EEQVMPTKVKPVETKVDKPRQIEE--VDAMLKEEPTFLESDEIKPFEVTEEGD-IKMTAQ 467 Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725 V + P+ +EWFK+ V ++ + T + G +L I D G YT + +N G Sbjct: 468 VTGKPQPS--VEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGL 525 Query: 2726 AVSTASIKIED 2736 T + ++D Sbjct: 526 GRRTFDVSVDD 536 Score = 46.8 bits (106), Expect = 4e-04 Identities = 49/199 (24%), Positives = 76/199 (38%), Gaps = 19/199 (9%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P ++ W K+G + ++ L+I DDSG Y C T+ +G++ T S Sbjct: 577 PEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFS 636 Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791 + IE + ES R G F+S K D Sbjct: 637 VDIESKGPATKES--EKKKPRKGE----------------ERPKFVSDSTLEEFKITDEG 678 Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLDITHTYEEDSGIYTCKA 2850 V+ + P ++EW ++K L R S D V L I DSG+Y CK Sbjct: 679 ELRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKV 738 Query: 2851 TNSKGSATTSGSLRCTGDK 2869 T+ G++T S + G++ Sbjct: 739 TSDVGTSTKSFDVTIEGER 757 Score = 46.8 bits (106), Expect = 4e-04 Identities = 90/411 (21%), Positives = 152/411 (36%), Gaps = 63/411 (15%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I G D YS A N+ G+ KL + K ++P + + L D + Sbjct: 1847 LVIEGCAPDDDAVYSVVAMNEAGKDTSKGKLLVHSRPKQEQPTEPAGPRITKELVDAEVE 1906 Query: 3168 HFE-CTVVP--VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 T+V V + + + W + + R+ +D L I+ + D G Y C Sbjct: 1907 ETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTC 1966 Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284 NK G+ T A + + ELE+++ AEPP+F Sbjct: 1967 TVRNKMGDTSTSAEV-------------------IVEELEAVES---------EAEPPRF 1998 Query: 3285 ITQIQDVTKLVEGQSAHFEARLVPVDDPD-LKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343 +T ++D +L EG + LV D + ++WF + K+L R+ D + Sbjct: 1999 VTPLKD-QELEEGSTVDM---LVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMT 2054 Query: 3344 IL-YCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLED 3402 I E+ + Y+ VA N G T A + KE + ++ + D Sbjct: 2055 ISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKE------------AAEVTPVEEVVD 2102 Query: 3403 SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKS 3462 + V AP+ PL++ ++ EG++ E + + P+ +V WY + Sbjct: 2103 AAV------------PAPIIIKPLNDEIDVLEGDSVRLECVI--SGGPDAQVLWYKDDYL 2148 Query: 3463 LKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 L+ R D L I +D EY C N G + V+ Sbjct: 2149 LEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVE 2199 Score = 46.4 bits (105), Expect = 6e-04 Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840 ++ +G + E ++T +P ++W+KD +P+ S +I + SL I+ +D Sbjct: 1373 KISDGGDLTLEVKIT--GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDT 1430 Query: 841 GSYTVRAVNKLGEAISTASIRVAA 864 YT +A NK G ++ ++A Sbjct: 1431 AKYTCKATNKSGTTTRNINVDISA 1454 Score = 46.4 bits (105), Expect = 6e-04 Identities = 75/308 (24%), Positives = 110/308 (35%), Gaps = 25/308 (8%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130 TG ++WF K + R+ + L I T D G+Y +N +G Sbjct: 1486 TGTPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVS 1545 Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190 +AE+ V + +G P+ T E GQ F V VD +K + + Sbjct: 1546 EAELVVMTVSEAEDEGIIPKVTPTPGKTEITIPGQKPKFG--PVEVDIKGLKDK---ERE 1600 Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINC-YGKGGVYL 3249 + I FG V + I D V A F I+ G ++ Sbjct: 1601 RLTSEASIAGRKPFGAVDMSIT-APGEDKKPTVTEA-EFTPVAFKPVEISVPIGDEAPFI 1658 Query: 3250 E---SLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARL 3306 + +PD + LE + TP+ E P I + D ++EG SA E Sbjct: 1659 SLKGAKKPDLPVLAKPLEVIMPVS----FTPAEEAPFIIKPLNDEIDVLEGDSARLEC-- 1712 Query: 3307 VPVDDPDLKVEWFYNGKKLPHGHR--YRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364 V PD V W+ + L R Y T D +I+ +E EY+CV TN G Sbjct: 1713 VISGGPDAHVFWYKDDYLLEEDERVSYETDGDQHTLIIQSAELDDE--AEYKCVVTNIAG 1770 Query: 3365 RDSTKANL 3372 K L Sbjct: 1771 SVDVKTEL 1778 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 2/105 (1%) Query: 934 EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993 E + + V W KD V A +R+T + L I V D G YTC N +G Sbjct: 1916 EFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDT 1975 Query: 994 TTSANLTIVTKKDIIAESQHPGGLE--KIQYLEDASRYSKRTEEE 1036 +TSA + + + + +E++ P + K Q LE+ S E + Sbjct: 1976 STSAEVIVEELEAVESEAEPPRFVTPLKDQELEEGSTVDMLVETD 2020 Score = 46.0 bits (104), Expect = 8e-04 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 8/89 (8%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI-----TKTHD 2430 PV QPL++++ I+E A FD R+ G P VEWF++ + ++D R D Sbjct: 967 PVIIQPLKSLE-IKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023 Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 S+ I V ED G Y C A N G+ Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAGK 1052 Score = 46.0 bits (104), Expect = 8e-04 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228 +E+ + P F++PL V E + + LEC + G P ++ W G V R T Sbjct: 1154 VEKPEGAAPEFIKPLK-VLEVFETQPVRLECSVT--GTPEPQITWLKGGDVVKEDDRITT 1210 Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271 +D L+I + D GEY A+N G A T A + V E Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLVNE 1253 Score = 46.0 bits (104), Expect = 8e-04 Identities = 65/267 (24%), Positives = 107/267 (40%), Gaps = 30/267 (11%) Query: 2904 PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLT 2963 P T+ P P E L L +V+ +P +I+W+ + K ++ + ++ Sbjct: 1353 PITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVD 1412 Query: 2964 SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023 +L +V D+ YTCKA NK G + V ++ L+ + PK E L+ Sbjct: 1413 YRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISA---LMPEGEAPKYVEPLK 1469 Query: 3024 KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIE 3083 + +EDS TG P FK+ + E H +I D S ++ Sbjct: 1470 SDEIVEDS----SFTMNVKFTGTPIPEVQWFKENKPVREDDRVH----IIRESDSSTLV- 1520 Query: 3084 WFYNGKTI---EASHRIRTVYAFGMVVLE----ILGTKTTDSGTYSCRATNKWGQAEISV 3136 KT+ E S++I FG V E ++ + + T G+ EI++ Sbjct: 1521 ---ITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEAEDEGIIPKVTPTPGKTEITI 1577 Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKD 3163 GQKP+F +I+GLKD Sbjct: 1578 --------PGQKPKFGPVEVDIKGLKD 1596 Score = 46.0 bits (104), Expect = 8e-04 Identities = 54/219 (24%), Positives = 87/219 (39%), Gaps = 29/219 (13%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F++ L + +EG + + VE + I+WF +NK L R+ T D + ++ I Sbjct: 1998 FVTPLKDQELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTI 2055 Query: 2836 TH-TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894 + T E+++ Y A N G A T + +E E AE Sbjct: 2056 SPVTLEDEAMYYKVVAENVAGEAVTDAEVI-------------------VEVKEAAEVTP 2096 Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954 + + V D P P I P+ E ++EG + LE + PD ++ WY + +L Sbjct: 2097 VEE-----VVDAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLL 2149 Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 E+ R +D TL + D Y C N G Sbjct: 2150 EEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP F LK + + E Q V LE V +P +I W K G + R+ + FD Sbjct: 1161 APEFIKPLKVLE-VFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITTVFDGETC 1217 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 L+I DD G Y C A N G+A + A + + + Sbjct: 1218 VLNITVSCLDDEGEYKCLAMNDFGKAATVAELLVNE 1253 Score = 45.6 bits (103), Expect = 0.001 Identities = 28/121 (23%), Positives = 58/121 (47%), Gaps = 4/121 (3%) Query: 636 PPQFI--VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693 PP+F V + +GG + E +I G+P +I+W K+ + ++ S + +R Sbjct: 1360 PPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPVKPSQKIRVDYRDDI 1417 Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753 SL ++ + D+ +YTC+A + +G + ++ ++ E L+ + +ED Sbjct: 1418 HSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGEAPKYVEPLKSDEIVEDS 1477 Query: 754 S 754 S Sbjct: 1478 S 1478 Score = 45.6 bits (103), Expect = 0.001 Identities = 24/83 (28%), Positives = 39/83 (46%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F H+ K D V+ + +P +I+WF ++KP+ + + + SL I Sbjct: 1363 FSPHVGEGPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTI 1422 Query: 2836 THTYEEDSGIYTCKATNSKGSAT 2858 +D+ YTCKATN G+ T Sbjct: 1423 VGASPDDTAKYTCKATNKSGTTT 1445 Score = 45.6 bits (103), Expect = 0.001 Identities = 48/227 (21%), Positives = 87/227 (38%), Gaps = 12/227 (5%) Query: 2518 SELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG-----FVTLDINS 2572 +E EG ++ RV G P EW+ N L +F D +L I Sbjct: 2214 TEANEGDVVRFDIRVA--GKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEG 2271 Query: 2573 VVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEM 2632 D +Y A+N AG A + ++ + +VPE Sbjct: 2272 CAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVPEE 2331 Query: 2633 FVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK 2692 + +AP+F +K+ + ++EG+ + V+ +P+ I+W++ + R Sbjct: 2332 EAASPETKAPVFIETMKNIE-VMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRFV 2388 Query: 2693 --STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 + TL I + + D+G YTC A N + E A + ++ + Sbjct: 2389 HIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435 Score = 45.2 bits (102), Expect = 0.001 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 P P+FI ++ V ++ E Q E + +P ++ W G + R T D Sbjct: 1157 PEGAAPEFIKPLK-VLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITTVFD 1213 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 +L+I ++ GEY+C+A N G+ +T A L Sbjct: 1214 GETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAEL 1249 Score = 44.8 bits (101), Expect = 0.002 Identities = 65/302 (21%), Positives = 108/302 (35%), Gaps = 28/302 (9%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 TG +EW + + I L I D GTY+ +N+ G Sbjct: 95 TGKPQPSVEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRR 154 Query: 3135 SVKLECVDKSK-----GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189 + + D K KP+F + + TV P+ ++ W +G Sbjct: 155 TFDVSVDDTRKTIPKDAVKPKFIEDGSFVP-FQSTDEGDVRLTVKVTGKPEPEVTWTKDG 213 Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYL 3249 +P+ ++ +L I DSG Y C + G+ +++ +G Sbjct: 214 KPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESEGPAPK 273 Query: 3250 ESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPV 3309 ES + R+L L+G E PKF++ V + + Sbjct: 274 ES-------EKRKL--LKG----------EERPKFVSD-STVEEFKITDEGELRLTVKVT 313 Query: 3310 DDPDLKVEWFYNGKKLPHGHR-YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDST 3368 P +VEW + K L R + D GIV+L I +SG Y+C ++ +G ST Sbjct: 314 GKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVG-TST 372 Query: 3369 KA 3370 K+ Sbjct: 373 KS 374 Score = 44.8 bits (101), Expect = 0.002 Identities = 42/146 (28%), Positives = 63/146 (43%), Gaps = 10/146 (6%) Query: 3567 LILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG-----FVILEIGG 3621 L + E ++A F+ R+ VEWF +G+ L R I+D L I Sbjct: 976 LEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIED 1033 Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHK 3681 V DAG Y C A N G+AT + LQV + I + P H G++ K+ + Sbjct: 1034 VIPEDAGEYECVAVNEAGKATSTATLQVLTK--ISELDKTPVHTVEGSDITMKVAVSGTP 1091 Query: 3682 REEIT-IEDEKPNPPRFTVEIKDNID 3706 R E+ +D++ R IK +D Sbjct: 1092 RTEVEWYKDDRKLSNRKPYVIKTTVD 1117 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 3/109 (2%) Query: 768 QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827 + P+++ PL+ E+ E + + T P V+W+K+ +P+ R+ I Sbjct: 1460 EAPKYVEPLKS-DEIVEDSSFTMNVKFT--GTPIPEVQWFKENKPVREDDRVHIIRESDS 1516 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPE 876 +L I +D GSY + N G+A+S A + V S + IP+ Sbjct: 1517 STLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEAEDEGIIPK 1565 Score = 44.8 bits (101), Expect = 0.002 Identities = 66/285 (23%), Positives = 103/285 (36%), Gaps = 34/285 (11%) Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS-MRVEWFHNGKPLLTG 3603 V+ L PP F T D L E S+ L+ + +S + ++WF + K L+ Sbjct: 1983 VEELEAVESEAEPPRFVTPLKDQELEEGSTVDM---LVETDGTSPIHIKWFKDNKELVPD 2039 Query: 3604 SRVKTINDFGFVILEIGGVYQRDAGLY-TCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662 R D + I V D +Y A N GEA ++ V+ ++ + P Sbjct: 2040 ERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTP--- 2096 Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722 +EE + D P + D IDV EG V +C + Sbjct: 2097 ------------VEEVV---------DAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS-- 2133 Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 G P ++ W+ + R+ D L I D EY C TN GS Sbjct: 2134 GGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVK 2193 Query: 3783 AKITCSAKRDI-VLESQLPQGMSGEKIKELERGRISDAPKEEPIV 3826 ++ + V++ L + E ++ R I A K EP+V Sbjct: 2194 TELIVEEGISLPVIKEGLKDTEANE--GDVVRFDIRVAGKPEPVV 2236 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/117 (25%), Positives = 55/117 (47%), Gaps = 6/117 (5%) Query: 2622 KEAAMNKVPEMFVDTGVQQAPIF--TTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF 2679 K A + ++PE VD +++ P F + +K ++ EG + L QV + P+ +EW Sbjct: 50 KLACLQRIPEE-VDAMLKEEPTFLESDEIKPFEVTEEGD-IKLTVQVTGKPQPS--VEWL 105 Query: 2680 KNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 K+ V ++ + T + +L I D G YT + +N G T + ++D Sbjct: 106 KDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDD 162 Score = 43.6 bits (98), Expect = 0.004 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 2/93 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 PQ + K EV EG V +E + D R+ WY + P+ RF+T +D G +L Sbjct: 871 PQIQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSL 928 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 I +D Y C G T+ + V+ Sbjct: 929 RIHDIVIDDEAEYRCDIATDRGVVSMTTELIVE 961 Score = 43.6 bits (98), Expect = 0.004 Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFG-----FVTLDLVDVYERDSGIYTCKAY 2989 V + P +EW+ +G+ L+ RF + D +L + DV D+G Y C A Sbjct: 988 VRVRGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAV 1047 Query: 2990 NKRGEAFTSSTVYCTSKDNLIERT 3013 N+ G+A +++T+ +K + +++T Sbjct: 1048 NEAGKATSTATLQVLTKISELDKT 1071 Score = 43.6 bits (98), Expect = 0.004 Identities = 72/352 (20%), Positives = 127/352 (36%), Gaps = 66/352 (18%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167 +P F+ E + G+ F + E P +DW+H + R+ + Sbjct: 1257 KPKFIETTHDTEIIT-GESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRFLINTEEDTS 1313 Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQG 2227 L I D G Y C +N GE + L V + I D P Sbjct: 1314 TLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTP------------- 1360 Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287 P+ SP V E G + +G E ++ +P I+++ + K ++ Sbjct: 1361 ---------PEFSP--HVGE--GPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPVKP 1405 Query: 2288 AARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347 + + + + SL I P+D +Y+ KA N G T T ++ + P Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG--------TTTRNINVDISALMP 1457 Query: 2348 EGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPT 2407 EG + P + +PL++ D I E + + + G P Sbjct: 1458 EG------------------------EAPKYVEPLKS-DEIVEDSSFTMNVKF--TGTPI 1490 Query: 2408 LKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 +V+WF+ K + + R+ + ++ I+ +DEG Y SN G+ Sbjct: 1491 PEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGK 1542 Score = 43.2 bits (97), Expect = 0.005 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 4/81 (4%) Query: 87 GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146 G+ + K+ G P P V+WT+ P+ + + + E L I++ P D G Y C Sbjct: 191 GDVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDR--YILTIREASPDDSGSYRC 248 Query: 147 TARNQYGEA--ICSVYIQPEG 165 T + G++ SV I+ EG Sbjct: 249 TLTSDVGKSTRTFSVDIESEG 269 Score = 43.2 bits (97), Expect = 0.005 Identities = 38/149 (25%), Positives = 62/149 (41%), Gaps = 13/149 (8%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 PQ K + +EG + E + D +I W K+ + S RF + F G SL Sbjct: 871 PQIQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSL 928 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756 + + I D EY C +A + V+ +T +E P +Q ++ LE + Sbjct: 929 RIHDIVIDDEAEYRC------DIATDRGVVSMTTELIVEEAVLMPVIIQPLKSLEIKEEN 982 Query: 757 QHQESIEEQTSQRP-----QFIRPLQDLG 780 + + + S +P + R LQDLG Sbjct: 983 AARFDVRVRGSPQPLVEWFKDGRQLQDLG 1011 Score = 42.7 bits (96), Expect = 0.007 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 7/100 (7%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG---- 2033 P +P+K+ E+ E + + + P VEW+ +GR +Q RF D Sbjct: 967 PVIIQPLKSLEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDK 1024 Query: 2034 -YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 +L I ED G Y C A N G+A +T++++V K Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 42.7 bits (96), Expect = 0.007 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 2/101 (1%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 +AP I LN + EG SA EC I PD + V WY + +L+ R D Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLECVISGGPDAH--VFWYKDDYLLEEDERVSYETDGDQ 1745 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942 L I + +D EY C N G L V+ S+ Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISL 1786 Score = 42.7 bits (96), Expect = 0.007 Identities = 47/217 (21%), Positives = 83/217 (38%), Gaps = 23/217 (10%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP+F+ PLK EG + + +E G + I+W K+ + + R T + Sbjct: 1995 PPRFVTPLKDQELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHT 2052 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755 + + + ++D Y VAE A VT + I ++++ ++ Sbjct: 2053 MTISPVTLEDEAMYY------KVVAENVAGEAVTDA-------------EVIVEVKEAAE 2093 Query: 756 YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815 E + + P I+PL D ++ EG + E ++ P +V WYKD + Sbjct: 2094 VTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLLEE 2151 Query: 816 SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852 RI + +L I +D Y N G Sbjct: 2152 DERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188 Score = 42.3 bits (95), Expect = 0.009 Identities = 33/125 (26%), Positives = 47/125 (37%), Gaps = 5/125 (4%) Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759 E I+V EG V +C+ D RI W+ + P R T D G +L I Sbjct: 875 EYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHD 932 Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819 I D EY C G + T ++ + VL + Q + +IKE R Sbjct: 933 IVIDDEAEYRCDIATDRGVVSMTTELIV---EEAVLMPVIIQPLKSLEIKEENAARFDVR 989 Query: 3820 PKEEP 3824 + P Sbjct: 990 VRGSP 994 Score = 42.3 bits (95), Expect = 0.009 Identities = 28/114 (24%), Positives = 49/114 (42%), Gaps = 5/114 (4%) Query: 3950 IKKYTSEVYLTEDDLYDVDKKQ--PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKV 4007 + K S + D+ V+K + P F+ ++ + E + + EC + G P ++ Sbjct: 1137 VTKNDSGTFTQMFDITIVEKPEGAAPEFIKPLKV-LEVFETQPVRLECSVT--GTPEPQI 1193 Query: 4008 EWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061 W G + +R T ++D +N +D GEY C A N +G T A Sbjct: 1194 TWLKGGDVVKEDDRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVA 1247 Score = 42.3 bits (95), Expect = 0.009 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 3/101 (2%) Query: 2234 VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI 2293 VE+P+ + P F+ L+ VFE + EC V +P +I + G ++ R Sbjct: 1154 VEKPEGAAPEFIKPLK-VLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITT 1210 Query: 2294 TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 FD L+I +D GEY A+N G + + V Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 8/119 (6%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 +PE + P++ P+K +++ F ++ G V+W K+ +PV R+ Sbjct: 1456 MPEG-EAPKYVEPLKSDEIVEDSSFT---MNVKFTGTPIPEVQWFKENKPVREDDRVHII 1511 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020 L I D G Y N G+A + A L ++T ++E++ G + K+ Sbjct: 1512 RESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMT----VSEAEDEGIIPKV 1566 Score = 41.9 bits (94), Expect = 0.012 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 7/95 (7%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-----STHDFS 2829 V I L ++ KE + F+ V S P +EWF + + L R+ D Sbjct: 968 VIIQPLKSLEIKEENAARFDVRVRGSPQPL--VEWFKDGRQLQDLGRFMIIDDVDDQDKE 1025 Query: 2830 YVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864 SL I ED+G Y C A N G AT++ +L+ Sbjct: 1026 LYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQ 1060 Score = 41.9 bits (94), Expect = 0.012 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 3/106 (2%) Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100 + P+++ PLK +++IVE S F V+ V+W+ K + +R+ + Sbjct: 1460 EAPKYVEPLK-SDEIVEDSS--FTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDS 1516 Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSI 1146 L I +D G Y +V N G+A A + V T S + I Sbjct: 1517 STLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEAEDEGI 1562 Score = 41.5 bits (93), Expect = 0.016 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 2/82 (2%) Query: 491 PKFVE--RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548 P F+E V E + L + G P P + W KD VP+ P+ + I + +L Sbjct: 69 PTFLESDEIKPFEVTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHITITEEDDTYSL 128 Query: 549 DIPRAKASDAAWYQCTAQNVAG 570 I D Y N AG Sbjct: 129 VIKEPTKKDEGTYTVEVSNEAG 150 Score = 41.5 bits (93), Expect = 0.016 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 9/121 (7%) Query: 2619 IQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEW 2678 I ++ E+ V+ V P+ LKS + E + V R P +EW Sbjct: 945 IATDRGVVSMTTELIVEEAVLM-PVIIQPLKSLEIKEENAARF---DVRVRGSPQPLVEW 1000 Query: 2679 FKNGVTLTTGARLKSTFDFG-----LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733 FK+G L R D L +L I + +D+G Y C A N G+A STA+++ Sbjct: 1001 FKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQ 1060 Query: 2734 I 2734 + Sbjct: 1061 V 1061 Score = 41.5 bits (93), Expect = 0.016 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 8/101 (7%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG--- 1233 PV +QPL + + E + R+ G P VEWF +GR + RF D Sbjct: 967 PVIIQPLKSLE-IKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023 Query: 1234 --FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 +L I D GEY AVN G A ++A ++V+ + Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 41.5 bits (93), Expect = 0.016 Identities = 31/98 (31%), Positives = 40/98 (40%), Gaps = 4/98 (4%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 PKFI + E V F + E P ++WY L+ R+ + +L Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRFLINTEEDTSTL 1315 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFT--KATISCKKLP 3925 I V D G Y C ND GED T K T+ KK P Sbjct: 1316 IIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKP 1353 Score = 41.5 bits (93), Expect = 0.016 Identities = 25/83 (30%), Positives = 36/83 (43%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP+F + T + L G T +VEWF + KP+K R + D + Sbjct: 2438 APEFQKEPEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHS 2497 Query: 1370 LDLLSVYPEDSGVYTCQATNQLG 1392 L + P+DSG YT A + G Sbjct: 2498 LKIKGGKPDDSGKYTVVAESPAG 2520 Score = 41.5 bits (93), Expect = 0.016 Identities = 21/59 (35%), Positives = 31/59 (52%) Query: 794 LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852 LT PT +VEW+KD +P+ + R+ SL I + +D+G YTV A + G Sbjct: 2462 LTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAG 2520 Score = 41.1 bits (92), Expect = 0.021 Identities = 29/113 (25%), Positives = 50/113 (44%), Gaps = 6/113 (5%) Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635 +AP LK+ EI E + F + +V+W+ NKP++ R Sbjct: 1460 EAPKYVEPLKSDEIVED--SSFTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDSS 1517 Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRL 1688 L I +P+D G+Y N G+AV+ +V + E++ EG +P++ Sbjct: 1518 TLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVS----EAEDEGIIPKV 1566 Score = 41.1 bits (92), Expect = 0.021 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 3/87 (3%) Query: 909 PEF-KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 PEF K P K + G + L G T +VEW KD +PV+ + R+ Sbjct: 2439 PEFQKEPEKSTFDVNTGDDVSLD--LTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEH 2496 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQAT 994 +L IK D+G YT A + G+ T Sbjct: 2497 SLKIKGGKPDDSGKYTVVAESPAGRDT 2523 Score = 40.7 bits (91), Expect = 0.028 Identities = 33/140 (23%), Positives = 54/140 (38%), Gaps = 8/140 (5%) Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764 E I P K+I V E + E + G R+ W ++ VP+ S R T D Sbjct: 865 EGIDTGPQIQEYSKEIEVVEGSSVTIECQ--SSGAEDARITWYKDDVPLGDSPRFETAFD 922 Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824 G +L + + +D Y C + G ++ L V+ + + +Q ++ L Sbjct: 923 NGLCSLRIHDIVIDDEAEYRCDIATDRGVVSMTTELIVEEAVLMPV------IIQPLKSL 976 Query: 1825 EDSSRYQRREDVEVAVNQAP 1844 E R DV V + P Sbjct: 977 EIKEENAARFDVRVRGSPQP 996 Score = 40.7 bits (91), Expect = 0.028 Identities = 36/121 (29%), Positives = 48/121 (39%), Gaps = 5/121 (4%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G VEW KD R + LTI S + DAG Y C N G T Sbjct: 1089 GTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYKCVTKNDSGTFTQM 1148 Query: 997 ANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIV 1056 ++TIV K E P ++ ++ LE R E V T +P+ LKG + + Sbjct: 1149 FDITIVEK----PEGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEPQITW-LKGGDVVK 1203 Query: 1057 E 1057 E Sbjct: 1204 E 1204 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 2/101 (1%) Query: 2636 TGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF 2695 T ++AP L ++EG LE + P+ + W+K+ L R+ Sbjct: 1684 TPAEEAPFIIKPLNDEIDVLEGDSARLECVISG--GPDAHVFWYKDDYLLEEDERVSYET 1741 Query: 2696 DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 D TL I S DD Y C TN+ G + +E+ Sbjct: 1742 DGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEE 1782 Score = 40.3 bits (90), Expect = 0.037 Identities = 28/118 (23%), Positives = 45/118 (38%), Gaps = 2/118 (1%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E ++ + P F+ ++ + + + P VEW KD P++ I Sbjct: 59 EEVDAMLKEEPTFLES-DEIKPFEVTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHI 117 Query: 820 TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV-AARSTVTADLGIPE 876 T SL I +D G+YTV N+ G T + V R T+ D P+ Sbjct: 118 TITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPK 175 Score = 40.3 bits (90), Expect = 0.037 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGAR-LKSTFDFGLVTLSINSLRNDDSGIYTCKAT 2720 L V+ P ++EW K+ L R + S D G+V L I + DSG+Y CK T Sbjct: 680 LRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVT 739 Query: 2721 NLLGEAVSTASIKIE 2735 + +G + + + IE Sbjct: 740 SDVGTSTKSFDVTIE 754 Score = 40.3 bits (90), Expect = 0.037 Identities = 61/286 (21%), Positives = 108/286 (37%), Gaps = 43/286 (15%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E+ KP+F D I G F + E G T V+W + V + R Sbjct: 1251 VNEALVKPKFIETTHDT-EIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRFLIN 1307 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021 L I+ V D G+Y C N G+ T + LT++ KK I + P Sbjct: 1308 TEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTP------- 1360 Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEW 1079 +S E GPL KI +G E ++ EP+ + ++W Sbjct: 1361 -----PEFSPHVGE-----------GPL----KISDGGDLTLEVKITGEPKPE----IQW 1396 Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139 + + K + + +I+ + +L I +D+ YT A N +G + ++ + Sbjct: 1397 FKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALM 1456 Query: 1140 SIDTSSIHRGLYEKTRHIEESKFV-------EPMYQIEEISKSKPV 1178 + + + +E+S F P+ +++ ++KPV Sbjct: 1457 PEGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQWFKENKPV 1502 Score = 40.3 bits (90), Expect = 0.037 Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 2/89 (2%) Query: 68 EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127 E P + + K+ + + K G P P V W ++ P+ E ++ + ++ Sbjct: 1458 EGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQWFKENKPVREDDR--VHIIRESD 1515 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 +L+I + P DEG Y N +G+A+ Sbjct: 1516 SSTLVITKTVPDDEGSYKIVLSNPFGKAV 1544 Score = 40.3 bits (90), Expect = 0.037 Identities = 61/293 (20%), Positives = 103/293 (35%), Gaps = 23/293 (7%) Query: 2939 NDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998 ++ + + W + + +R + +D TL + D G+YTC NK G+ TS Sbjct: 1919 SEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTS 1978 Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058 + V + + + P+ L K Q LE+ + + D G P FKD Sbjct: 1979 AEVIVEELEAVESEAEPPRFVTPL-KDQELEEGSTVDMLVETD---GTSPIHIKWFKD-- 2032 Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118 L+P + + + TI + +V + G TD+ Sbjct: 2033 ----------NKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDA 2082 Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178 AE++ E VD + P + + + +G S EC + Sbjct: 2083 EV----IVEVKEAAEVTPVEEVVDAAV-PAPIIIKPLNDEIDVLEGDSVRLECVI--SGG 2135 Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 PD ++ WY + + RI +D L I + D EY C N G Sbjct: 2136 PDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188 Score = 39.9 bits (89), Expect = 0.049 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 3/92 (3%) Query: 1435 IIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494 I+++ P F+ +P + V E Q V EC + + ++ W K G V R Sbjct: 1153 IVEKPEGAAPEFI-KPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRIT 1209 Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 + D L+I +D G Y C A+N G Sbjct: 1210 TVFDGETCVLNITVSCLDDEGEYKCLAMNDFG 1241 Score = 39.9 bits (89), Expect = 0.049 Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 12/115 (10%) Query: 1690 QLEDTSKYQRHSAQD-EVITQAPVFTMPMKDIRVA---ENQAAHFEAR--------LIPV 1737 +L DT KY +A D + IT V T+ K+I E + + F+ L Sbjct: 2406 KLGDTGKYTCIAANDVDEITCEAVLTVKPKEIAPEFQKEPEKSTFDVNTGDDVSLDLTVT 2465 Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792 G P +VEW ++ P++ + RL +L +K P+DSG YT A + G Sbjct: 2466 GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAG 2520 Score = 39.5 bits (88), Expect = 0.065 Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 8/113 (7%) Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155 +T E +VEE A PV + ++ ++E ARF RV G P+P V W +G + + Sbjct: 954 MTTELIVEE--AVLMPVIIQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLG 1011 Query: 4156 RYKLTYD------GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202 R+ + D +Y I D G+ E + L+V+ + Sbjct: 1012 RFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 39.5 bits (88), Expect = 0.065 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 +VE+ + P F+ + V E + R C VTG P+P++ WL G+ + R Sbjct: 1153 IVEKPEGAAPE-FIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITTV 1211 Query: 4161 YDG 4163 +DG Sbjct: 1212 FDG 1214 Score = 39.5 bits (88), Expect = 0.065 Identities = 21/71 (29%), Positives = 32/71 (45%) Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852 F NV+ + P +++WF NKP+ R + +L IT T +D G Y +N Sbjct: 1479 FTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSN 1538 Query: 2853 SKGSATTSGSL 2863 G A + L Sbjct: 1539 PFGKAVSEAEL 1549 Score = 39.5 bits (88), Expect = 0.065 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 5/120 (4%) Query: 758 HQESIEEQTSQR--PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815 H +EQ ++ P+ + L D E++E A+ VS+ V W KD + A Sbjct: 1880 HSRPKQEQPTEPAGPRITKELVD-AEVEETTPVTLVAEF--VSEGETSVTWTKDAHRVVA 1936 Query: 816 SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875 +R+T + +L I +D G YT NK+G+ ++A + V V ++ P Sbjct: 1937 DNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPP 1996 Score = 39.1 bits (87), Expect = 0.086 Identities = 36/142 (25%), Positives = 59/142 (41%), Gaps = 7/142 (4%) Query: 3511 KVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVD-TLTPEAES-GNPPEFTTTPSDLI 3568 +V + +I++S P +GT A +G GTV T E P+ ++ Sbjct: 825 RVDDRLTLIVKSPSPSD-QGTYKCTATNKG--GTVTRTFQVNMEGIDTGPQIQEYSKEIE 881 Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAG 3628 + E SS EC+ D+ R+ W+ + PL R +T D G L I + D Sbjct: 882 VVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEA 939 Query: 3629 LYTCKATNRHGEATVSCKLQVK 3650 Y C G +++ +L V+ Sbjct: 940 EYRCDIATDRGVVSMTTELIVE 961 Score = 39.1 bits (87), Expect = 0.086 Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 8/88 (9%) Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG--- 2564 P+ Q L E+ E A ++ RV G P EW+ +G +L+ RF D Sbjct: 967 PVIIQPLKS-LEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023 Query: 2565 --FVTLDINSVVANDAGLYMCKAINRAG 2590 +L I V+ DAG Y C A+N AG Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAG 1051 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 2245 VTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDI 2304 + E V EG + ECQ D RI +Y + L + RF FD G SL I Sbjct: 873 IQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRI 930 Query: 2305 QHCVPEDAGEY 2315 V +D EY Sbjct: 931 HDIVIDDEAEY 941 Score = 38.7 bits (86), Expect = 0.11 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 2/84 (2%) Query: 918 QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977 +I + EG E + D+ R+ W KD P+ S R T F+ G +L I + + Sbjct: 879 EIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVID 936 Query: 978 DAGHYTCRAYNAIGQATTSANLTI 1001 D Y C G + + L + Sbjct: 937 DEAEYRCDIATDRGVVSMTTELIV 960 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 2/82 (2%) Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840 E+ EG + E Q + D R+ WYKD P+ S R + F+ G SL I + +D Sbjct: 881 EVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDE 938 Query: 841 GSYTVRAVNKLGEAISTASIRV 862 Y G T + V Sbjct: 939 AEYRCDIATDRGVVSMTTELIV 960 Score = 38.7 bits (86), Expect = 0.11 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 6/117 (5%) Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE 1628 +V++ AP LK +E+ E Q E + + ++ W +K R T Sbjct: 1153 IVEKPEGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITT 1210 Query: 1629 TNNFGFVALDI-MSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK--KSIYLESQHE 1682 + L+I +SCL +D G Y C A+N G+A T +V+ K ++E+ H+ Sbjct: 1211 VFDGETCVLNITVSCL-DDEGEYKCLAMNDFGKAATVAELLVNEALVKPKFIETTHD 1266 Score = 38.7 bits (86), Expect = 0.11 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 4/108 (3%) Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE 1628 +V+E + T+ + EI G+ F R+ T V+WYH + + RF Sbjct: 1250 LVNEALVKPKFIETT-HDTEIITGESVWF--RVKYEGSPTPDVDWYHEDTLVSDTGRFLI 1306 Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT-SGIAIVHSKKSI 1675 L I P D G Y C N GE +T S + ++ KK I Sbjct: 1307 NTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPI 1354 Score = 38.7 bits (86), Expect = 0.11 Identities = 29/167 (17%), Positives = 69/167 (41%), Gaps = 4/167 (2%) Query: 3927 IILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLV 3986 +I+++ P + + +A S++ + E D PP F + + L Sbjct: 1315 LIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTPPEFSPHV-GEGPLK 1373 Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEY 4046 + ++ G+P +++WF + KP+ + Y ++ P+D+ +Y Sbjct: 1374 ISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKY 1433 Query: 4047 LCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEAS 4093 C+ATN G + + ++ + + PK+++ ++ +E S Sbjct: 1434 TCKATNKSGTTTRNINVDIS---ALMPEGEAPKYVEPLKSDEIVEDS 1477 Score = 38.3 bits (85), Expect = 0.15 Identities = 42/201 (20%), Positives = 81/201 (40%), Gaps = 15/201 (7%) Query: 3402 DSMVRRKDTSVEEEK-----GKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456 + M K T +E++K G P F+ P L+ + + T +P +++W Sbjct: 1338 EDMTVSKLTVIEKKKPITDVGTPPEFS-PHVGEGPLKISDGGDLTLEVKITGEPKPEIQW 1396 Query: 3457 YWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516 + + K +K + R L I P+D+ +Y C+A N G ++ + Sbjct: 1397 FKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISA-- 1454 Query: 3517 NIILESQLPKGMEG-TIDKIAALEGYSGTV---DTLTPEAE--SGNPPEFTTTPSDLILS 3570 ++ E + PK +E D+I ++ V T PE + N P +I Sbjct: 1455 -LMPEGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRE 1513 Query: 3571 ENSSAHFECRLIPVNDSSMRV 3591 +SS + +P ++ S ++ Sbjct: 1514 SDSSTLVITKTVPDDEGSYKI 1534 Score = 38.3 bits (85), Expect = 0.15 Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 2/95 (2%) Query: 907 QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966 + P P+ D+I + EG A E + G V W KD +E R++ + Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745 Query: 967 VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 L I+S + D Y C N G L + Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIV 1780 Score = 38.3 bits (85), Expect = 0.15 Identities = 41/168 (24%), Positives = 71/168 (42%), Gaps = 9/168 (5%) Query: 3897 EDSGEYICRAVNDFGEDFTK--ATISCKKLPDIILQNQVPRGMKRSEALTQMEATIK-KY 3953 +D+ E + + F +D K TIS L D + +V EA+T E ++ K Sbjct: 2031 KDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKE 2090 Query: 3954 TSEVYLTEDDLYDVDKKQP-PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFN 4012 +EV E+ VD P P + + + ++E ++ + EC ++ G P+ +V W+ + Sbjct: 2091 AAEVTPVEEV---VDAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKD 2145 Query: 4013 GKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060 L R D + +D EY C TN+ G + K Sbjct: 2146 DYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVK 2193 Score = 37.9 bits (84), Expect = 0.20 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%) Query: 1847 ITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI 1906 I + + ++ EG S EC+ D R+ WY + L R+ T+ D G +L I Sbjct: 873 IQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRI 930 Query: 1907 LTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 + +D EY C + G + L V+ Sbjct: 931 HDIVIDDEAEYRCDIATDRGVVSMTTELIVE 961 Score = 37.9 bits (84), Expect = 0.20 Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 5/95 (5%) Query: 3979 IQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG-----YVAM 4033 IQ SL E + G P VEWF +G+ L RF I D ++ Sbjct: 970 IQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSL 1029 Query: 4034 NFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068 V PED+GEY C A N G + A ++ K Sbjct: 1030 VIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064 Score = 37.9 bits (84), Expect = 0.20 Identities = 19/72 (26%), Positives = 35/72 (48%) Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 + W K+ + R+ D TL+I+ DD G+YTC N +G+ ++A + +E Sbjct: 1925 VTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVE 1984 Query: 2736 DRHWLLGESLHP 2747 + + E+ P Sbjct: 1985 ELEAVESEAEPP 1996 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/94 (23%), Positives = 37/94 (39%), Gaps = 1/94 (1%) Query: 2365 PEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR 2424 PE + + ++ P F + I + + + G P VEW +++ + Sbjct: 58 PEEVDAMLKEEPTFLES-DEIKPFEVTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEH 116 Query: 2425 ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 IT T + S+ I +DEG Y SN G Sbjct: 117 ITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAG 150 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/118 (22%), Positives = 49/118 (41%), Gaps = 3/118 (2%) Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819 E + + +P+FI D E+ G + F + PT V+WY + ++ + R Sbjct: 1248 ELLVNEALVKPKFIETTHDT-EIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRF 1304 Query: 820 TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQ 877 +L I ++ D G+Y N GE ++ + + V + D+G P + Sbjct: 1305 LINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTPPE 1362 Score = 37.1 bits (82), Expect = 0.35 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGAR-LKSTFDFGLVTLSINSLRNDDSGIYTCKAT 2720 L V+ P ++EW K+ L R + S D G+V L I + DSG+Y C+ + Sbjct: 306 LRLTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVS 365 Query: 2721 NLLGEAVSTASIKIE 2735 + +G + + + IE Sbjct: 366 SDVGTSTKSFDVTIE 380 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 2/88 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 FI L + E + EC+V + +P +I W + R + D L+I Sbjct: 1164 FIKPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITTVFDGETCVLNI 1221 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 T + +D G Y C A N G A T L Sbjct: 1222 TVSCLDDEGEYKCLAMNDFGKAATVAEL 1249 Score = 36.7 bits (81), Expect = 0.46 Identities = 27/104 (25%), Positives = 38/104 (36%), Gaps = 2/104 (1%) Query: 3546 DTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR 3605 D E G PEF L + E EC + + ++ W G + R Sbjct: 1150 DITIVEKPEGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDR 1207 Query: 3606 VKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 + T+ D +L I D G Y C A N G+A +L V Sbjct: 1208 ITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 36.7 bits (81), Expect = 0.46 Identities = 33/104 (31%), Positives = 45/104 (43%), Gaps = 6/104 (5%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPN-LKVEWYWNGKSLKAGSRFRTF 3472 E + + P F PL + E L EG L TD + + ++W+ + K L R Sbjct: 1990 ESEAEPPRFVTPLKDQE-LEEGSTVDM---LVETDGTSPIHIKWFKDNKELVPDERHTFT 2045 Query: 3473 CDFGFVILEISPTYPEDSGEYL-CRAYNNYGEAVTTASMKVQGK 3515 D + ISP ED Y A N GEAVT A + V+ K Sbjct: 2046 KDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK 2089 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 4/84 (4%) Query: 1978 PQFGK-PIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 P+F K P K+ +V G V L+ T+T PT +VEW+ + +PV+ R + Sbjct: 2439 PEFQKEPEKSTFDVNTGDDVSLDLTVT--GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEH 2496 Query: 2036 ALDILYAYAEDTGTYMCKATNAVG 2059 +L I +D+G Y A + G Sbjct: 2497 SLKIKGGKPDDSGKYTVVAESPAG 2520 Score = 36.3 bits (80), Expect = 0.61 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Query: 87 GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146 G+ K ++ G P P V W + P+ ++ + T SL+IK+ DEG YT Sbjct: 86 GDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHITITEEDDT--YSLVIKEPTKKDEGTYTV 143 Query: 147 TARNQYG 153 N+ G Sbjct: 144 EVSNEAG 150 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 5/124 (4%) Query: 3947 EATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMK 4006 +AT K T+ + D + + + P++V ++S + E + F + G P + Sbjct: 1436 KATNKSGTTTRNINVDISALMPEGEAPKYVEPLKSDEIV---EDSSFTMNVKFTGTPIPE 1492 Query: 4007 VEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG--MDETKAVIK 4064 V+WF KP+ +R I + + P+D G Y +N +G + E + V+ Sbjct: 1493 VQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVM 1552 Query: 4065 TTGK 4068 T + Sbjct: 1553 TVSE 1556 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 3/95 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +AP + LKS D++VE + + P +++WFK + R+ + Sbjct: 1460 EAPKYVEPLKS-DEIVEDSSFTMNVKFTGTPIP--EVQWFKENKPVREDDRVHIIRESDS 1516 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 TL I DD G Y +N G+AVS A + + Sbjct: 1517 STLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVV 1551 Score = 36.3 bits (80), Expect = 0.61 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 2/78 (2%) Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIAS 1107 P K T + G + V + T VEW+ + K + R++ +L I Sbjct: 2445 PEKSTFDVNTGDDVSLDLTVTGKP--TPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKG 2502 Query: 1108 VRAEDSGVYTVVARNAAG 1125 + +DSG YTVVA + AG Sbjct: 2503 GKPDDSGKYTVVAESPAG 2520 Score = 36.3 bits (80), Expect = 0.61 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847 GD++ + V + PT K+EWF ++KP+ R + SL I +DSG YT Sbjct: 2455 GDDVSLDLTV--TGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYT 2512 Query: 2848 CKATNSKGSAT 2858 A + G T Sbjct: 2513 VVAESPAGRDT 2523 Score = 35.9 bits (79), Expect = 0.80 Identities = 19/77 (24%), Positives = 33/77 (42%), Gaps = 2/77 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG ++ EC + D +I W+ ++ PL R+++ D SL I +D Y Sbjct: 884 EGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEY 941 Query: 2847 TCKATNSKGSATTSGSL 2863 C +G + + L Sbjct: 942 RCDIATDRGVVSMTTEL 958 Score = 35.9 bits (79), Expect = 0.80 Identities = 19/88 (21%), Positives = 37/88 (42%), Gaps = 2/88 (2%) Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379 + TVEG+++ ++ + G VEW+ + + + + D L + S P D Sbjct: 1073 VHTVEGSDITMKVAVS--GTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSD 1130 Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKD 1407 +G Y C N G + ++ K + Sbjct: 1131 AGTYKCVTKNDSGTFTQMFDITIVEKPE 1158 Score = 35.9 bits (79), Expect = 0.80 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 3/93 (3%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P F+ PLK ++ E Q E V + +T W G + +RI T D Sbjct: 1162 PEFIKPLK-VLEVFETQPVRLECSVTGTPEPQIT--WLKGGDVVKEDDRITTVFDGETCV 1218 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 L+I +D G Y +A N G+A A + V Sbjct: 1219 LNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 3/101 (2%) Query: 1709 QAPVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767 +AP P+ D I V E +A E + G P V W ++ +E R++ D Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLEC--VISGGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745 Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 L ++ +D Y C N G + L V+ SL Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISL 1786 Score = 35.9 bits (79), Expect = 0.80 Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 8/148 (5%) Query: 1536 CRSTTDIVRST--QNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEG 1592 C D V S NEAG + + + H ++ T A P T L + E++E Sbjct: 1852 CAPDDDAVYSVVAMNEAGKD---TSKGKLLVHSRPKQEQPTEPAGPRITKELVDAEVEET 1908 Query: 1593 QRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTC 1652 VS+ V W + + + +R T + L I +D G YTC Sbjct: 1909 TPVTLVAEF--VSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTC 1966 Query: 1653 RAINALGEAVTSGIAIVHSKKSIYLESQ 1680 N +G+ TS IV +++ E++ Sbjct: 1967 TVRNKMGDTSTSAEVIVEELEAVESEAE 1994 Score = 35.5 bits (78), Expect = 1.1 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 2/91 (2%) Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494 GE+ F + + P+ V+WY + RF + L I P D G Y Sbjct: 1272 GESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYK 1329 Query: 3495 CRAYNNYGEAVTTASMKVQGKRNIILESQLP 3525 C N+ GE +T + + V K+ I + P Sbjct: 1330 CIISNDAGEDMTVSKLTVIEKKKPITDVGTP 1360 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/96 (22%), Positives = 40/96 (41%), Gaps = 3/96 (3%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 P E PK++ ++ ++VE S + P+ V+WF K + R + Sbjct: 1457 PEGEAPKYVEPLKS-DEIVEDSSFTMNVKFTGTPIPE--VQWFKENKPVREDDRVHIIRE 1513 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 L I ++ G Y+ V +N G+ ++A L Sbjct: 1514 SDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAEL 1549 Score = 35.5 bits (78), Expect = 1.1 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643 V++ V W + ++ +RV D L I D GLYTC N+ G+ + Sbjct: 1918 VSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTST 1977 Query: 3644 SCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEE 3677 S ++ V+ + + E + P F + + Q+LEE Sbjct: 1978 SAEVIVEELEAVESEAE-PPRFVTPLKD-QELEE 2009 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 4/80 (5%) Query: 2380 QPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTI 2438 +P ++ ++ G D L G PT KVEWF+++K ++ + R+ K D + S+ I Sbjct: 2444 EPEKSTFDVNTGDDVSLD--LTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEH-SLKI 2500 Query: 2439 SHVRDEDEGVYMCRASNLLG 2458 + +D G Y A + G Sbjct: 2501 KGGKPDDSGKYTVVAESPAG 2520 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 3441 EARLTP--TDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAY 3498 + RLT T P +V W +GK + IL I P+DSG Y C Sbjct: 192 DVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLT 251 Query: 3499 NNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530 ++ G++ T S+ ++ + ES+ K ++G Sbjct: 252 SDVGKSTRTFSVDIESEGPAPKESEKRKLLKG 283 Score = 35.1 bits (77), Expect = 1.4 Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 8/125 (6%) Query: 1180 VQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDI 1239 +Q S V EG ++ +EC + G R+ W+ + + RF+T +D G +L I Sbjct: 873 IQEYSKEIEVVEGSSVTIEC--QSSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRI 930 Query: 1240 IHATSADTGEYTVRAVNHLG--SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARR 1297 D EY G S T IV ++ I++ E+AAR Sbjct: 931 HDIVIDDEAEYRCDIATDRGVVSMTTELIVEEAVLMPVIIQPLKSLEIKE----ENAARF 986 Query: 1298 TKQVR 1302 +VR Sbjct: 987 DVRVR 991 Score = 35.1 bits (77), Expect = 1.4 Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 3976 VTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNF 4035 + + + +VE + ECQ + G + ++ W+ + PL RF +D G ++ Sbjct: 873 IQEYSKEIEVVEGSSVTIECQSS--GAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRI 930 Query: 4036 GWVYPEDSGEYLC 4048 + +D EY C Sbjct: 931 HDIVIDDEAEYRC 943 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Query: 2920 EHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYER 2979 E ++VEG + +E Q D +I WY + L RF+ D G +L + D+ Sbjct: 879 EIEVVEGSSVTIECQ--SSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVID 936 Query: 2980 DSGIYTCKAYNKRG 2993 D Y C RG Sbjct: 937 DEAEYRCDIATDRG 950 Score = 35.1 bits (77), Expect = 1.4 Identities = 17/48 (35%), Positives = 22/48 (45%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583 G R WY + V L RF T D G +L I+ +V +D Y C Sbjct: 896 GAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEYRC 943 Score = 35.1 bits (77), Expect = 1.4 Identities = 20/79 (25%), Positives = 32/79 (40%) Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDIL 3892 I+++ V EG +V P+ +EWY++ + L + Y + L I Sbjct: 1065 ISELDKTPVHTVEGSDITMKVAVSGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTIT 1124 Query: 3893 YVYAEDSGEYICRAVNDFG 3911 D+G Y C ND G Sbjct: 1125 SASPSDAGTYKCVTKNDSG 1143 Score = 35.1 bits (77), Expect = 1.4 Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 11/139 (7%) Query: 1991 EGHPVHLEATLTPVNDPTMRVEWYCNGRPV--QQGHRFKTTYDFGYVALDILYAYAEDTG 2048 EG + ++ ++ P VEWY + R + ++ + KTT D Y L I A D G Sbjct: 1077 EGSDITMKVAVS--GTPRTEVEWYKDDRKLSNRKPYVIKTTVD-DY-ELTITSASPSDAG 1132 Query: 2049 TYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE-RPKPIEEEQPGQ 2107 TY C N G + + K + + +K ++ LE +E +P +E G Sbjct: 1133 TYKCVTKNDSGTFTQMFDITIVEKP----EGAAPEFIKPLKVLEVFETQPVRLECSVTGT 1188 Query: 2108 RPVFLTALTSLENLKEGDR 2126 +T L + +KE DR Sbjct: 1189 PEPQITWLKGGDVVKEDDR 1207 Score = 35.1 bits (77), Expect = 1.4 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 3/95 (3%) Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962 V E PE+I P+ ++ E Q + LE V P+ +I W G V+++ R Sbjct: 1154 VEKPEGAAPEFIKPLKVL-EVFETQPVRLECSVT--GTPEPQITWLKGGDVVKEDDRITT 1210 Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997 D L++ D G Y C A N G+A T Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAAT 1245 Score = 34.7 bits (76), Expect = 1.9 Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 5/108 (4%) Query: 1976 EKPQFGKPIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034 E P KP+ + +V EG LE ++ P V WY + +++ R D Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082 L I A +D Y C TN G + + V+ G+ L + E Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVE--EGISLPVIKE 1791 Score = 34.7 bits (76), Expect = 1.9 Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 5/125 (4%) Query: 3701 IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYI 3760 + D IDV EG +C + G P + W+ + RV D L I Sbjct: 1696 LNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDGDQHTLIIQSA 1753 Query: 3761 YARDAGEYTCRATNKWGSATTTAKITCSAKRDI-VLESQLPQGMSGEKIKELERGRISDA 3819 D EY C TN GS ++ + V++ L + E E+ R I A Sbjct: 1754 ELDDEAEYKCVVTNIAGSVDVKTELIVEEGISLPVIKEGLKDTEANE--GEIVRFDIRVA 1811 Query: 3820 PKEEP 3824 K EP Sbjct: 1812 GKPEP 1816 Score = 34.7 bits (76), Expect = 1.9 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 86 GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145 G + + + G PTP V W + P+ + ++ + + SL IK P D G+YT Sbjct: 2455 GDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDD--EHSLKIKGGKPDDSGKYT 2512 Query: 146 CTARNQYG 153 A + G Sbjct: 2513 VVAESPAG 2520 Score = 34.3 bits (75), Expect = 2.5 Identities = 35/147 (23%), Positives = 57/147 (38%), Gaps = 4/147 (2%) Query: 1168 QIEEISKSKPVFVQPLSNPP-PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRF 1226 +++ + K +P F++ P V+E +I L ++ G P VEW + V+ Sbjct: 60 EVDAMLKEEPTFLESDEIKPFEVTEEGDIKLTVQVT--GKPQPSVEWLKDDVPVSPDEHI 117 Query: 1227 KTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAI 1285 + +L I T D G YTV N G + V V + R I D + I Sbjct: 118 TITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFI 177 Query: 1286 EQIQLLEDAARRTKQVREDITVMQAPQ 1312 E + + VR + V P+ Sbjct: 178 EDGSFVPFQSTDEGDVRLTVKVTGKPE 204 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/130 (21%), Positives = 54/130 (41%), Gaps = 5/130 (3%) Query: 3809 KELERGR--ISDAPKEE-PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865 K+ +G+ + PK+E P P+ ++ VEE+ V E + + + W Sbjct: 1870 KDTSKGKLLVHSRPKQEQPTEPAGPRITKELVDAEVEETTPVTLVA--EFVSEGETSVTW 1927 Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925 ++ + + +R D +L I +D G Y C N G+ T A + ++L Sbjct: 1928 TKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELE 1987 Query: 3926 DIILQNQVPR 3935 + + + PR Sbjct: 1988 AVESEAEPPR 1997 Score = 33.9 bits (74), Expect = 3.2 Identities = 16/64 (25%), Positives = 30/64 (46%), Gaps = 2/64 (3%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 + EG + +C+ G ++ W++++ + DS R D G S+ I + +DE Sbjct: 882 VVEGSSVTIECQ--SSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEA 939 Query: 2448 VYMC 2451 Y C Sbjct: 940 EYRC 943 Score = 33.9 bits (74), Expect = 3.2 Identities = 19/67 (28%), Positives = 29/67 (43%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDI 4169 P + L D + V EG+ AR C ++G P V W + + R DG H I Sbjct: 1690 PFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEEDERVSYETDGDQHTLI 1749 Query: 4170 PKTRQYD 4176 ++ + D Sbjct: 1750 IQSAELD 1756 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 2/80 (2%) Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493 EG + E + + +D ++ WY + L RF T D G L I +D EY Sbjct: 884 EGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEY 941 Query: 3494 LCRAYNNYGEAVTTASMKVQ 3513 C + G T + V+ Sbjct: 942 RCDIATDRGVVSMTTELIVE 961 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 2/72 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG +I + V S P ++EW+ +++ L + Y L IT D+G Y Sbjct: 1077 EGSDITMKVAV--SGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTY 1134 Query: 2847 TCKATNSKGSAT 2858 C N G+ T Sbjct: 1135 KCVTKNDSGTFT 1146 Score = 33.5 bits (73), Expect = 4.3 Identities = 16/50 (32%), Positives = 23/50 (46%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 +VEWY +++ L + + L I S P D+GTY C N G Sbjct: 1094 EVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYKCVTKNDSG 1143 Score = 33.5 bits (73), Expect = 4.3 Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 4/129 (3%) Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361 +E T P+ ++ L + E E T V L G+ + V W + + +R Sbjct: 1885 QEQPTEPAGPRITKELVDAEVEETTPVTLVAEFVSEGETS--VTWTKDAHRVVADNRVTI 1942 Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLE-- 1419 + L + +D G+YTC N++G+ TS + V + + E++ P + Sbjct: 1943 KTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPL 2002 Query: 1420 KIQYLEDTS 1428 K Q LE+ S Sbjct: 2003 KDQELEEGS 2011 Score = 33.5 bits (73), Expect = 4.3 Identities = 18/55 (32%), Positives = 27/55 (49%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718 G PT K+EW K+ + ++ + R + SL + DSG+YT A S G Sbjct: 2466 GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAG 2520 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/110 (21%), Positives = 50/110 (45%), Gaps = 6/110 (5%) Query: 2629 VPEMFVDTG-VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687 V E+ V+ V+ I TTH +++ G+ V+ + E P+ ++W+ ++ Sbjct: 1246 VAELLVNEALVKPKFIETTH---DTEIITGESVWFRVKYEGSPTPD--VDWYHEDTLVSD 1300 Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 R + TL I ++ D G Y C +N GE ++ + + + ++ Sbjct: 1301 TGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEK 1350 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 7/114 (6%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 +AP+++ L ++ E S + P P V+W+ K ++ R + Sbjct: 1460 EAPKYVEPLKSD-EIVEDSSFTMNVKFTGTPIPE--VQWFKENKPVREDDRVHIIRESDS 1516 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955 + L I +D G Y N G+AVS L V + + +++ E + K+ Sbjct: 1517 STLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMT----VSEAEDEGIIPKV 1566 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/85 (25%), Positives = 35/85 (41%), Gaps = 2/85 (2%) Query: 768 QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827 + P I+PL D ++ EG +A E ++ P V WYKD + R++ + Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLG 852 +L I +D Y N G Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAG 1770 Score = 33.1 bits (72), Expect = 5.7 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 3/99 (3%) Query: 3683 EEITIEDEKPNPPRFTVEI-KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 E + K P F E K DV G V D V G PT +++WF + +P Sbjct: 2427 EAVLTVKPKEIAPEFQKEPEKSTFDVNTGDDVSLDLTV--TGKPTPKVEWFKDDKPVKGT 2484 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780 R+ +L I D+G+YT A + G T Sbjct: 2485 RRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAGRDT 2523 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 5/124 (4%) Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720 E V + + W K+ + A +R T +L + ++ D G YTC + G Sbjct: 1916 EFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDT 1975 Query: 721 ETKAVLHVTPRATIERTSQHPETLQYI--QQLEDYSKYQHQESIEEQTSQRPQFIRPLQD 778 T A + V +E ++ P + + Q+LE+ S + + E P I+ +D Sbjct: 1976 STSAEVIVEELEAVESEAEPPRFVTPLKDQELEEGSTV---DMLVETDGTSPIHIKWFKD 2032 Query: 779 LGEL 782 EL Sbjct: 2033 NKEL 2036 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 3/72 (4%) Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843 V +EGD + V+ + P +EW ++ P+ T + SL I ++D Sbjct: 82 VTEEGD---IKLTVQVTGKPQPSVEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDE 138 Query: 2844 GIYTCKATNSKG 2855 G YT + +N G Sbjct: 139 GTYTVEVSNEAG 150 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/93 (23%), Positives = 33/93 (35%), Gaps = 2/93 (2%) Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158 P+ + P + L ++ EGD A EC + D H + W+ + + R Sbjct: 1680 PVSFTPAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAH--VFWYKDDYLLEEDERV 1737 Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191 D L I +D Y C TN G Sbjct: 1738 SYETDGDQHTLIIQSAELDDEAEYKCVVTNIAG 1770 Score = 32.3 bits (70), Expect = 9.9 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 2/88 (2%) Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232 ++ P ++PL++ V EG + LEC + G P V W+ + + R D Sbjct: 1686 AEEAPFIIKPLNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDG 1743 Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS 1260 L I A D EY N GS Sbjct: 1744 DQHTLIIQSAELDDEAEYKCVVTNIAGS 1771 Score = 32.3 bits (70), Expect = 9.9 Identities = 27/124 (21%), Positives = 47/124 (37%), Gaps = 5/124 (4%) Query: 3056 DIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT 3115 D +D+ EG A E + +G + W+ + +E R+ L I + Sbjct: 1698 DEIDVLEGDSARLECVI--SGGPDAHVFWYKDDYLLEEDERVSYETDGDQHTLIIQSAEL 1755 Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175 D Y C TN G + VK E + + P +++ E +G+ F+ V Sbjct: 1756 DDEAEYKCVVTNIAG--SVDVKTELIVEEGISLPVIKEGLKDTEA-NEGEIVRFDIRVAG 1812 Query: 3176 VDDP 3179 +P Sbjct: 1813 KPEP 1816 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/85 (27%), Positives = 33/85 (38%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 PEF P N+ L + +VEWF + KP+ R++ L Sbjct: 2439 PEFQKEPEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSL 2498 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEAT 3642 +I G D+G YT A + G T Sbjct: 2499 KIKGGKPDDSGKYTVVAESPAGRDT 2523 >SB_47305| Best HMM Match : I-set (HMM E-Value=0) Length = 5832 Score = 180 bits (437), Expect = 3e-44 Identities = 124/408 (30%), Positives = 190/408 (46%), Gaps = 24/408 (5%) Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 KP + T M+ C E E A F EF G+P P I+W+ PI F + L Sbjct: 825 KPEVITS-MRDCDCVEEETASFHCEFSGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSL 883 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528 I + +ED+ + VA N G A L V EK P F ++ G Sbjct: 884 AISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEKH-------FAPEFEDWKDTIDALDG 936 Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588 Q V + T V G ++ WLK+G++++ + +I + L++ + P+D+G Y C A Sbjct: 937 QDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRA 996 Query: 4589 INSAGEARCDAECVV-SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647 N+AG D V +L D P +K +EP++ + EG + SC + Sbjct: 997 KNNAGIVSKDVTITVEALQKKGDTPTFMSK--------LEPIE---ITEGDDFQLSCNVT 1045 Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707 G+P P VQW++ + LIKPS+ F+ S + L + EA +D+G YKCV N+ G +V+ Sbjct: 1046 GRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFG--SVS 1103 Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767 +K VT + L + D+ EG A F +I + KP I+W I + F Sbjct: 1104 SKADVTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRF 1163 Query: 4768 QMIHEGNNA--VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 ++ + N +L I + +D GT C AT AAG+ A L V+ K Sbjct: 1164 KIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211 Score = 175 bits (426), Expect = 7e-43 Identities = 116/403 (28%), Positives = 184/403 (45%), Gaps = 21/403 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F K+++P V E+A +E G+P P + WY++ P+ + Q+ + + L I Sbjct: 631 PEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDLVPLLETRSIQLKSVGDEHTLEI 690 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 +D + A N+ GTA S ++ V+ QG P+ T ++ G+ Sbjct: 691 INATPDDEGKYKCEATNKAGTAFRSFDIKVKVAEPQGE----TPTITTEMTDIQAIDGED 746 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 +L VTG +V W K+GK ++ + R E+ L +D G+Y+CV N Sbjct: 747 CKLICHVTGEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISN 806 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650 G AE V + K PE+I ++D E + F C+ GKP Sbjct: 807 VFGSVSSAAEVKVEDRSLK-------------PEVITSMRDCDCVEEETASFHCEFSGKP 853 Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710 P ++W+ G I P F ++ + +L IS+ ED G+YKCVA N+AG+ T A+L Sbjct: 854 EPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAEL 913 Query: 4711 KVTQPDQADNLPALTPLRDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769 KV + A P +D + +GQ T + K KP I WL++G + T Q+ Sbjct: 914 KVNEKHFA---PEFEDWKDTIDALDGQDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQI 970 Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812 G+ L++ ED G +TCRA AG V + V++ Sbjct: 971 KCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEA 1013 Score = 171 bits (415), Expect = 2e-41 Identities = 111/392 (28%), Positives = 181/392 (46%), Gaps = 20/392 (5%) Query: 4419 PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDS 4478 P R E +G+P P + WYR++ + + ++ + V D+ Sbjct: 1812 PFRAKEKSDLEVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDA 1871 Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538 + A+NR G+A + N+ +E + + PSFT T + ++VT G+ +V Sbjct: 1872 GSYRCEAKNRVGSATRNFNVEIEVPKARDEA----PSFTTTLKPIDVTEGENHTFICRVH 1927 Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598 V W +N ++ PD R++ + TY L++ + +D+G+YEC+A N G+A C Sbjct: 1928 ARPEPSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCT 1987 Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 AE V+ K + K P I E K V+EG K+ G P+PTV+WY Sbjct: 1988 AEMTVN--------KREVK-----PVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYH 2034 Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718 G + FQ+++ D +TL I + + YKCVA+N+AGR T A L +T+ + A Sbjct: 2035 GSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREYA 2094 Query: 4719 DNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778 R I V EGQ A I ++ P ++W + L+ + G L Sbjct: 2095 PEFEDFDEKR-IAVREGQNAITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYL 2153 Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 I +D GT+ C+AT + G TS +++V Sbjct: 2154 EIRKATLDDAGTYICKATNSIG--STSRRIIV 2183 Score = 166 bits (403), Expect = 4e-40 Identities = 120/410 (29%), Positives = 178/410 (43%), Gaps = 21/410 (5%) Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465 K P F +K++ E EQ FE+ G P P+++WYR IK+ F I Sbjct: 528 KAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEEN 587 Query: 4466 SI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523 + L+I + EDS + VA N G NL V EK +V P F + + Sbjct: 588 DMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNEK-------VVQPEFDKEVKPI 640 Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583 V G+ ++ G V W K+ + ++ +TL I+ A P D GK Sbjct: 641 EVKHGEEATTSLEIKGKPKPKVTWYKDLVPLLETRSIQLKSVGDEHTLEIINATPDDEGK 700 Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643 Y+C A N AG A + V + +P+ +T P I + D +G+ + Sbjct: 701 YKCEATNKAGTAFRSFDIKVKVA----EPQGET------PTITTEMTDIQAIDGEDCKLI 750 Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 C + G+P P V+W+K K +K + S L ED G YKCV N G Sbjct: 751 CHVTGEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGS 810 Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763 V+ AA++KV D++ +T +RD E + A F + + K +P I+W I Sbjct: 811 VSSAAEVKV--EDRSLKPEVITSMRDCDCVEEETASFHCEFSGKPEPEIEWFCGPNPIVP 868 Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 F + EGN L I + ED G + C A+ AAG+ T A+L V K Sbjct: 869 GGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 165 bits (401), Expect = 8e-40 Identities = 180/759 (23%), Positives = 309/759 (40%), Gaps = 95/759 (12%) Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYD 4176 + + V+E + VTG+PKP V W +G + + + KL G H IPK D Sbjct: 387 EPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTND 446 Query: 4177 TGKIEVIXXXXXXXXXXXXXLKVIPRHDD---YRGVL-----KNAPRPWYDETTQYQRTE 4228 G+ + V+P+ G++ K W TT E Sbjct: 447 EGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGE 506 Query: 4229 TELEKTFEERQVLQRQGVIDHRPELKPKVIKE-----------------------PETEW 4265 +++ T E V + + ++KP+ +++ P EW Sbjct: 507 YKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEW 566 Query: 4266 QQSVKRKKNEEYYNKLQELENEQ---VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRY 4322 + R K+ + + EN+ VI E+R +S P V SN K+ A Sbjct: 567 YRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSG-----PYKCVASNDAGKTTALL- 620 Query: 4323 EDNLDQTEEVTEQRVQKKVTQKP-RIPDPSEST----VHGKE----------VHVAKQKQ 4367 NLD E+V + K+V KP + E+T + GK V + + + Sbjct: 621 --NLDVNEKVVQPEFDKEV--KPIEVKHGEEATTSLEIKGKPKPKVTWYKDLVPLLETRS 676 Query: 4368 TQKEVVGDKEITRKITSTE------TTEIEHKAQTQERVVEGPVKPSKP----PIFTKKM 4417 Q + VGD+ I +T E +KA T R + VK ++P P T +M Sbjct: 677 IQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVKVAEPQGETPTITTEM 736 Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-LIIRQVFVE 4476 + + E + GEP P ++W+++ P+K + + +F + I L R + +E Sbjct: 737 TDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPLKANHRL-VPSFEERMIALSFRPIKLE 795 Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536 D + V N G+ +A + VE++ + P + ++ + + + Sbjct: 796 DMGRYKCVISNVFGSVSSAAEVKVEDRS-------LKPEVITSMRDCDCVEEETASFHCE 848 Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596 +G ++ W + P R + EE +L I + +D+G Y+CVA N+AG+ Sbjct: 849 FSGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTT 908 Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQ 4655 AE V+ + PE E KD I A +GQ + S + GKP P + Sbjct: 909 TRAELKVN-------------EKHFAPE-FEDWKDTIDALDGQDVNISTWVRGKPKPEIV 954 Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715 W K + ++ + + Q+ D + L + + PED G Y C A N+AG V+ + V Sbjct: 955 WLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEAL 1014 Query: 4716 DQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774 + + P ++ L I + EG Q +T + +P +QW R+ LI + F+ ++GN Sbjct: 1015 QKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGN 1074 Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + L + +D G + C T G V + A + V K Sbjct: 1075 VSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113 Score = 163 bits (397), Expect = 2e-39 Identities = 113/394 (28%), Positives = 175/394 (44%), Gaps = 18/394 (4%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQIHTFSTKSILI 4469 P F + RV E +A E G+P P + WY+++ I + + I++ + Sbjct: 1215 PSFHGRQGRLRVKEGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFT 1274 Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529 I+Q ED + A N GTA + + VE K+ ++ P Q +VT G Sbjct: 1275 IKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEV----MIAPEIRQQLQAEDVTEGD 1330 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589 RL KV+G + WLKN + + + R K + T TL I D+ Y+ V Sbjct: 1331 DCRLTCKVSGYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVR 1390 Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649 N AGE A+ V TK PE++E +KD EG F+ K+ G Sbjct: 1391 NDAGEVSSSAKLKVIRKCTK-------------PEVLEKMKDVKGVEGDEATFNVKLSGY 1437 Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709 P P ++WY G I+ ++ SR +Y+L I + +D G YKC+A N AG+VT A+ Sbjct: 1438 PSPDIEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAE 1497 Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769 L+V + D A L + + QP + + + KPT+ W + G + + ++ Sbjct: 1498 LEVKERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEI 1557 Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803 G L I + EED G++ C A G E Sbjct: 1558 RSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAE 1591 Score = 159 bits (387), Expect = 4e-38 Identities = 112/393 (28%), Positives = 178/393 (45%), Gaps = 24/393 (6%) Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFA 4482 E +ARF+V +G P P ++WY+ I +S +I K LII+ + +D+ + Sbjct: 4 ESGEARFDVTIEGYPKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYK 63 Query: 4483 AVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP 4542 VA N G +L V+EK+ I P + + V G+ V LD +TG Sbjct: 64 CVATNDAGQTSLRGDLSVKEKQ------IAPQIKEKEQEPIEVFEGESVNLDLTITGKPK 117 Query: 4543 IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602 +V W K+GK ++ + D +Y L I +A P DSGKY+C A N G + D + Sbjct: 118 PEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVN 177 Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662 V K P + LK V EG+ +F+C + GKP P + WYK + Sbjct: 178 V-------------KVKGKAPTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQP 224 Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722 IK + + S TL I + +D+G YK N G ++ A L+VT P A Sbjct: 225 IKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVT-PKPA-KPE 282 Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG--NNAVLLI 4780 + + ++ EG A F+ + P +W + I + F++ + + L+I Sbjct: 283 VVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVI 342 Query: 4781 GNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + +D+G + C A+ AG+ A L VK+K Sbjct: 343 SDLRLDDSGAYQCIASNEAGECNLRADLKVKNK 375 Score = 155 bits (377), Expect = 6e-37 Identities = 112/411 (27%), Positives = 181/411 (44%), Gaps = 25/411 (6%) Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465 K P I K+ +P VFE E ++ G+P P + WY++ P++ + + + Sbjct: 84 KQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSIDLKSTDDS 143 Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525 L I + DS + A+N+ GT+ ++ V+ K + P+ T + V Sbjct: 144 YFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGK-------APTVTSELKPDKV 196 Query: 4526 TSGQLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584 G+ + VTG KP+ + W K+G+ ++ D R K + T TLLI + D G Y Sbjct: 197 QEGEQYKFTCAVTGKPKPV-ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTY 255 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644 + N G A+ V+ PKP A PE++ +++ EG F Sbjct: 256 KVEITNDLGSISSTADLEVT-------PKP------AKPEVVRKMENVESVEGSDAFFEV 302 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT--LRISEAFPEDEGDYKCVAYNSAG 4702 K G P+P +W+ K I+PS F+++ E T L IS+ +D G Y+C+A N AG Sbjct: 303 KFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAG 362 Query: 4703 RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 + A LKV A A L I V E Q + +T KP + W ++G + Sbjct: 363 ECNLRADLKVKNKPFAPEF-ADGDLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLH 421 Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 +T ++ G+ L I D G + C A+ G + + K+ V K Sbjct: 422 DTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPK 472 Score = 155 bits (375), Expect = 1e-36 Identities = 106/379 (27%), Positives = 172/379 (45%), Gaps = 21/379 (5%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P P I WY++ P+ ++ I + L I + ED+ + A NR G A S Sbjct: 2861 GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555 + V + +G PSF+L + + +L V+G + W KNGK V+ Sbjct: 2921 FEVDVTAPKVKGEA----PSFSLELRPIAAIEEFDSKLICHVSGKPKPQIKWTKNGKPVE 2976 Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614 D R + + DG L I + D+G YEC+A N+AG A VS Sbjct: 2977 SDGRLRT-DYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVS---------- 3025 Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674 N P I L D EG+ F ++ G P PTV+W+KG I + +Q+ Sbjct: 3026 ---RRNMRPLITHKLHDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGRRYQLMSN 3082 Query: 4675 ADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732 ++ ++L +S+ +D+G YKCVA N AG+ + A L V D + ++V Sbjct: 3083 EEQGKHSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIARDFGPEFDEEESPKPVIV 3142 Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792 EG+ AQ + + K ++W ++G + ++ + GN+ L+I + ED G++ Sbjct: 3143 NEGEEAQMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYK 3202 Query: 4793 CRATTAAGQVETSAKLVVK 4811 C A++ G+ + L VK Sbjct: 3203 CVASSTNGRSSRTFDLSVK 3221 Score = 155 bits (375), Expect = 1e-36 Identities = 116/413 (28%), Positives = 176/413 (42%), Gaps = 21/413 (5%) Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 ++ P K P F K++ P E + +F + G P P I+W R+ +++ Sbjct: 5239 IQAPEAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGYPEPEIEWTRDGVSMESDERVTTW 5298 Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520 S L I DS ++ +N G A SA LVV K ++ P + Sbjct: 5299 YDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKTQR-------PRLSDNM 5351 Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580 + + T G R + + T + W K+ ++ R + EEDG YTL+I E D Sbjct: 5352 KELFATVGGEARFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSD 5411 Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640 SG Y+ VA N AG+ V +T A P E L+ + EG+ + Sbjct: 5412 SGTYKFVASNKAGKTTFLGYLEV---------MEKTVAPEFPDR--ETLEQVVGVEGREV 5460 Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700 E S + G P P+V+WYK KL+ SK +S + D + + I A E G Y+C A NS Sbjct: 5461 ELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEATNS 5520 Query: 4701 AGRV--TVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757 G ++ P + PA T PL+ I + EG +F +IT P ++W R+ Sbjct: 5521 NGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVPVVEWYRD 5580 Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 + + +G +LL+ T D G F C G V +SA L V Sbjct: 5581 DRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633 Score = 151 bits (367), Expect = 1e-35 Identities = 108/406 (26%), Positives = 172/406 (42%), Gaps = 16/406 (3%) Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467 +KP + +KM E + R EV G P+P ++W+R+N + N+ + I S Sbjct: 4847 TKPEV-AEKMTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTST 4905 Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 L+IR D+ + + N G NL++ E+ P + V V Sbjct: 4906 LVIRNCTTNDTGPYKVIGTNECGIGGAVLNLIIHERE------FGPEFIDEEGEYVKVVR 4959 Query: 4528 GQ-LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586 + + + V G +V W K+G + R T+ L I +D+G Y C Sbjct: 4960 SEGVANITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMC 5019 Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAAN-APPEIIEPLKDKIVAEGQAIEFSCK 4645 A + G +C C++ + A PK + P I ++D EG I F Sbjct: 5020 EARSKLG--KCFRSCILDVQAV---PKEEVDHGQIVKPVITRKIRDAQGEEGSNIRFEIH 5074 Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705 + P P V+WY+G + +Q+S Y+L I+ +D G YK VA N AG T Sbjct: 5075 VKSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSST 5134 Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765 A++ V A + +T I + G I K KP++ W ++G I + Sbjct: 5135 SRAEVVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIRGKPKPSVVWYKDGNKILTSR 5194 Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 + Q+ G+ L+I T E GT++C AT+ G TSAK V+ Sbjct: 5195 NVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLG--NTSAKFDVQ 5238 Score = 150 bits (363), Expect = 3e-35 Identities = 117/406 (28%), Positives = 177/406 (43%), Gaps = 22/406 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS--IL 4468 P +KM R E +A F V+ D P P I+WY I + F+I T IL Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCSYIL 1176 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528 I V ++D+ A N G A+L VEEK V PSF + V G Sbjct: 1177 FIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKN-------VAPSFHGRQGRLRVKEG 1229 Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECV 4587 + + +++G V W K+ + + RN I +Y I +A P+D G Y+C Sbjct: 1230 REASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCE 1289 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647 A N G A + P + K + A PEI + L+ + V EG +CK+ Sbjct: 1290 ARNDVGTA------FETFPIDVE-VKQEVMIA---PEIRQQLQAEDVTEGDDCRLTCKVS 1339 Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707 G P PT++W K ++L+ + F+ TL I D YK V N AG V+ + Sbjct: 1340 GYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSS 1399 Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767 AKLKV + + L ++D+ EG A F +++ P I+W I + + Sbjct: 1400 AKLKVIR--KCTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRY 1457 Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + + L I + +D GT+ C A+ AG+V A+L VK + Sbjct: 1458 KFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKER 1503 Score = 148 bits (359), Expect = 9e-35 Identities = 107/380 (28%), Positives = 164/380 (43%), Gaps = 16/380 (4%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA--K 4493 G P P + WYR+ + ++ I + + I + +ED+ + A +R GTA Sbjct: 3408 GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRS 3467 Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553 C+ + V I +V G V+ T++TG V W + K Sbjct: 3468 CTLEIKVPSMGGPEEKKISKALIGQGDNDVQAVEGWKVQFQTRITGYPYPHVEWYRGTIK 3527 Query: 4554 VQPDIRNKILE--EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611 + + KI + EDG Y+L++ + D G Y+C+A NSAG + C V KDK Sbjct: 3528 LHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDV-----KDK 3582 Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671 A P E ++ V EGQ I I KP V WYK +L++ +K + Sbjct: 3583 QY----APEIPGH--EDRQELNVPEGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDI 3636 Query: 4672 SRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDI 4730 D Y L I A PED G YKC ++ G + +K PD + P L+ L + Sbjct: 3637 RSRGDHYYLVIPSAAPEDSGLYKCEGVSTLGTSSKTFDVKAGVPDGSRVTPKFLSHLNSL 3696 Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790 V EG A+ ++ K +PT++W ++ LI + GN L+ +D G Sbjct: 3697 DVDEGDSAKLTCKMFGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGA 3756 Query: 4791 FTCRATTAAGQVETSAKLVV 4810 + C AT G +SA +VV Sbjct: 3757 YRCTATNQEGSTSSSAVIVV 3776 Score = 148 bits (358), Expect = 1e-34 Identities = 106/388 (27%), Positives = 173/388 (44%), Gaps = 23/388 (5%) Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 V P + P F+ +++P E ++ G+P P IKW + P+++ + Sbjct: 2925 VTAPKVKGEAPSFSLELRPIAAIEEFDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTD 2984 Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520 + L I QV +D+ + +A N GT SA L V RR R P T Sbjct: 2985 YDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVS--RRNMR-----PLITHKL 3037 Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL--EEDGTYTLLILEAYP 4578 ++ G+ R D +VTG V W K + R +++ EE G ++L++ + Sbjct: 3038 HDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNA 3097 Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638 D G Y+CVA N AG+A A V +D P+ +P K IV EG+ Sbjct: 3098 DDDGIYKCVAQNLAGKASTRAMLDV---IARDFG-PEFDEEESP-------KPVIVNEGE 3146 Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698 + + G+P V+W+K K + S+ + + + L I PEDEG YKCVA Sbjct: 3147 EAQMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVAS 3206 Query: 4699 NSAGRV--TVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755 ++ GR T +KV +P +LPA + LR + EG+ +F ++ + PT++W Sbjct: 3207 STNGRSSRTFDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWF 3266 Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNT 4783 ++ I F+ +G +L+ T Sbjct: 3267 KDDTPIKHEDRFRTYFDGRVCMLVFRKT 3294 Score = 147 bits (356), Expect = 2e-34 Identities = 101/405 (24%), Positives = 174/405 (42%), Gaps = 19/405 (4%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P+ T+K++ + E RFE+ P P ++WYR + + + P +QI L I Sbjct: 5052 PVITRKIRDAQGEEGSNIRFEIHVKSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTI 5111 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTSGQ 4529 V +D+ + VA N+ G++ A +VV++K + P +TA + +T G Sbjct: 5112 TGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDKP------LAPKVAEMTATGPITITRGN 5165 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589 + L+ + G V W K+G K+ +I Y L+IL + +G Y C A Sbjct: 5166 QLNLNVTIRGKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEAT 5225 Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649 + G + + P +AA P ++ L + EG ++FSCK+ G Sbjct: 5226 SKLGNTSAKFDVQIQAP----------EAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGY 5275 Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709 P P ++W + ++ + + TL I A D G YKC N++G + +A+ Sbjct: 5276 PEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAE 5335 Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769 L V Q L ++++ G A+F+ + + KP I W ++ + + M Sbjct: 5336 LVVGGKTQRPRLS--DNMKELFATVGGEARFEVTMKATPKPKICWYKDEITLRSRDRYTM 5393 Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 E L+I D+GT+ A+ AG+ L V KT Sbjct: 5394 KEEDGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKT 5438 Score = 147 bits (355), Expect = 3e-34 Identities = 111/417 (26%), Positives = 182/417 (43%), Gaps = 29/417 (6%) Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 +E P + P FT ++P V E E F P P + WYR I PD + Sbjct: 1893 IEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWYRNKNEIV--PDGRSR 1950 Query: 4461 T-FSTKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL 4518 T F ++ LI++ + ++D+ + +A N G A C+A + V ++ V P Sbjct: 1951 TTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKRE-------VKPVIKE 2003 Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP 4578 ++ V+ G ++ KV+G V W +V R ++ +E +TL I + Sbjct: 2004 VSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGD 2063 Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA--E 4636 Q + Y+CVA N+AG A+ V+ T+ AP E +K +A E Sbjct: 2064 QAAASYKCVAFNNAGRTTYRADLVI------------TEREYAPE--FEDFDEKRIAVRE 2109 Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 GQ + I +P P V+WYKGD L+ + + Y L I +A +D G Y C Sbjct: 2110 GQNAITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICK 2169 Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756 A NS G + + V +A ++ LR + V EG + ++ +PT++W R Sbjct: 2170 ATNSIGSTSRRIIVDVEALKEAPVF--VSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYR 2227 Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + + ++M +G L + +D G + C T +AG +SA+L V K Sbjct: 2228 DNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKK 2284 Score = 144 bits (348), Expect = 2e-33 Identities = 126/538 (23%), Positives = 225/538 (41%), Gaps = 40/538 (7%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P K + +G KF + G P PV+SW + P+ + ++ T +L Sbjct: 185 PTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDGTTS--TL 242 Query: 132 LIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPEGXXXXXXXXXXXXXYRHVSETV-EH 188 LIK + D+G Y N G + + + P+ S+ E Sbjct: 243 LIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAFFEV 302 Query: 189 KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLR--EVSFRESITKRYVG 246 K G E ++K+ ++ ++ D + + LR + + I G Sbjct: 303 KFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAG 362 Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306 E +++ ++ P +P +++E ++ ++GNP+P VTW+K+G +L Sbjct: 363 ECNLRADLKVKNK--PFAPEFADGDLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQL 420 Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC----------------IVTS 350 ++ K ++ T + L + +D G Y A NP G ++ S Sbjct: 421 HDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIES 480 Query: 351 GYLAVESPTESYVQ-------DQRSQY---ITDTQQRETE-ERIEISEKALAPQFVKVCQ 399 G + ++ E+ + D +Y +T+ T I + + + P+F++ + Sbjct: 481 GLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVE 540 Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLS 458 D E + F+ + G P P V W+ +I+D I +E + ++L+I Sbjct: 541 DVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTE 600 Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518 DSG CVA N +G+T L+V EK VV P+F + + V+ GE + G P Sbjct: 601 DSGPYKCVASNDAGKTTALLNLDVNEK--VVQPEFDKEVKPIEVKHGEEATTSLEIKGKP 658 Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 P++TW KD VP++ +++ + G TL+I A D Y+C A N AG TA R+ Sbjct: 659 KPKVTWYKDLVPLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAG-TAFRS 715 Score = 142 bits (343), Expect = 8e-33 Identities = 151/643 (23%), Positives = 250/643 (38%), Gaps = 55/643 (8%) Query: 95 LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154 + G P+P VSW R L++ K+ +R T + + GD G Y C A+N+ G Sbjct: 1827 INGKPSPDVSWYRDDRLLLDGRKHELRKRGNT--YRFTVFNVSAGDAGSYRCEAKNRVGS 1884 Query: 155 AICSVYIQPEGXXXXXXXXXXXXXYR--HVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212 A + ++ E + V+E H E S + Sbjct: 1885 ATRNFNVEIEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWYRNKNEIV 1944 Query: 213 TDHSSTDDFKVDTFEYRL----LREVSFRESITKRYVGESDVQISTEID-RSLGPVSPPK 267 D S F +T++ L +++ E I +G++ ++ R + PV Sbjct: 1945 PDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREVKPV---- 2000 Query: 268 IAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRN 327 I + + ++ EG A +V++SG P P V W+ R+++ ++ ++ Sbjct: 2001 IKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQV------------- 2047 Query: 328 TQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISE 387 TQ+ D Y L+ G + Y V ++ R+ Y D + I+E Sbjct: 2048 TQEGD---YHTLSIRDVGDQAAASYKCV-----AFNNAGRTTYRAD---------LVITE 2090 Query: 388 KALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNES 445 + AP+F + R V EG+ + + RP P+V W+ D + D KI L Sbjct: 2091 REYAPEFEDFDEKRIAVREGQNAITNMTIRARPSPDVEWYKGDTLLMSD--RKIDLKTIG 2148 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505 G + L I TL D+G C A N G T+ + ++V ++ AP FV + L V EG Sbjct: 2149 GLYYLEIRKATLDDAGTYICKATNSIGSTSRRIIVDVEALKE--APVFVSKLRPLFVTEG 2206 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 + V + G P P + W +D P+ + ++ DG +L + A D Y C Sbjct: 2207 DNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVI 2266 Query: 566 QNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYI 625 N AGS + A L ++++ + + V R I Sbjct: 2267 TNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSI 2326 Query: 626 PPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF 685 E + Y + P V E I+F+ R+ G P I W K+G+ + RF Sbjct: 2327 KVRNE-KFYGDDELKEP---VVVQESDAINFKVRVR--GKPVPTIVWYKDGEMVRDVRRF 2380 Query: 686 TSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 R + S + +D+G YTC A + G LHV Sbjct: 2381 EIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHV 2423 Score = 138 bits (334), Expect = 1e-31 Identities = 97/395 (24%), Positives = 162/395 (41%), Gaps = 17/395 (4%) Query: 4419 PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDS 4478 P + Q V G+P P + WY++ I S + QI + LII E + Sbjct: 5158 PITITRGNQLNLNVTIRGKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHA 5217 Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538 ++ A ++ G ++ ++ + P+F N G +V+ KVT Sbjct: 5218 GTYSCEATSKLGNTSAKFDVQIQAPEAAPKA----PAFLKQLLPQNAREGDVVKFSCKVT 5273 Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598 G ++ W ++G ++ D R + TL I A DSG Y+C N++G A Sbjct: 5274 GYPEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSS 5333 Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 AE VV K Q P + + +K+ G F + P P + WYK Sbjct: 5334 AELVVG-------GKTQR------PRLSDNMKELFATVGGEARFEVTMKATPKPKICWYK 5380 Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718 + ++ + M YTL I E D G YK VA N AG+ T L+V + A Sbjct: 5381 DEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKTVA 5440 Query: 4719 DNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778 P L +V EG+ + T + +P+++W +EG L+ + + G+ + Sbjct: 5441 PEFPDRETLEQVVGVEGREVELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYV 5500 Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 I + E +G + C AT + G L ++++ Sbjct: 5501 WIPSAKHEHSGRYRCEATNSNGTAHRDFVLNIQAQ 5535 Score = 137 bits (331), Expect = 2e-31 Identities = 94/368 (25%), Positives = 160/368 (43%), Gaps = 22/368 (5%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G+P P I W ++ ++N+ QI + L++ +V ED+ ++ A+N G Sbjct: 947 GKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKD 1006 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555 + VE +++G P+F + + +T G +L VTG +V W ++ ++ Sbjct: 1007 VTITVEALQKKGD----TPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIK 1062 Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615 P R K + L + EA D G Y+CV N+ G A+ V + Sbjct: 1063 PSRRFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLR------ 1116 Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675 PE+++ + D EG F+ KI P P ++WY G I F++ Sbjct: 1117 -------PEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTDK 1169 Query: 4676 DE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733 + Y L I + +D G KC A N+AG+ V A L+V + + A + + V Sbjct: 1170 ENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKNVAPSFHGRQ--GRLRVK 1227 Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALI-PETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792 EG+ A +I+ K KP++ W ++ +I E + + G++ I ED GT+ Sbjct: 1228 EGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYK 1287 Query: 4793 CRATTAAG 4800 C A G Sbjct: 1288 CEARNDVG 1295 Score = 134 bits (324), Expect = 2e-30 Identities = 103/407 (25%), Positives = 170/407 (41%), Gaps = 22/407 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P +++Q V E + R + G P P ++W + N + ++ F+ L I Sbjct: 1315 PEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTI 1374 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 R V + D+ + V N G SA L V K P ++V G Sbjct: 1375 RNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK-------CTKPEVLEKMKDVKGVEGDE 1427 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 + K++G D+ W +++ R K +D Y+L I + QD G Y+C+A N Sbjct: 1428 ATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASN 1487 Query: 4591 SAGEARCDAECVVSLPATKD-KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649 AG+ AE V +D P + K + +EPL+ ++ Q +E S + G+ Sbjct: 1488 EAGKVTQRAELEVK---ERDYAPIFEEK------QFLEPLEIQV---RQPVEVSYHVRGR 1535 Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709 P PTV W+K K ++ K+ ++ +TL I + ED G YKC+A N G + Sbjct: 1536 PKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFE 1595 Query: 4710 LKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768 ++V + P LT LR + E + + P+ +WL++ + Sbjct: 1596 VQVEGVKPKEEAPKLTSQLRSARITESDDFELACDVKGTPDPSYEWLKDDKPVKFDRHLS 1655 Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL-VVKSKT 4814 +G L D G++T A G +SA L +VKSK+ Sbjct: 1656 SSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKS 1702 Score = 134 bits (323), Expect = 2e-30 Identities = 102/406 (25%), Positives = 167/406 (41%), Gaps = 21/406 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F + V E + A+ + G+P P ++W++++ I N+ + LI Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTLIF 3746 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 V ++D + A N+ G+ SA +VV + P ++V+ G Sbjct: 3747 ETVNIQDRGAYRCTATNQEGSTSSSAVIVVNR-------ASITPRIIEKPRDVDAVDGTD 3799 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 + +V G V W K+ R +I Y+L+I G Y+C+A N Sbjct: 3800 AKFTVRVEGFPQPKVTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTYKCIATN 3859 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650 AG + A C L TK P + P EP+ +V EG + + GKP Sbjct: 3860 DAG--KVTAHC--HLDVTKQDFAPIVAGSEMP----EPI---VVREGCEVSMMANVRGKP 3908 Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710 PTV+W+K +L+ + + + + L + + D G YK VA N G L Sbjct: 3909 APTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNL 3968 Query: 4711 KVT--QPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767 VT P + + P +T L + V EG +F ++ P+IQW ++ I Sbjct: 3969 NVTAIAPKEKWSSPIFVTELSPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRI 4028 Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + +G+ LLIG ED G + +G +SAKL V+ + Sbjct: 4029 RTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREE 4074 Score = 133 bits (322), Expect = 3e-30 Identities = 103/417 (24%), Positives = 167/417 (40%), Gaps = 24/417 (5%) Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 VE K P F K++P + E + + G P P ++W+R+ IK S F+ Sbjct: 1011 VEALQKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKAS 1070 Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520 S L +++ ++D V+ V N G+ A++ V +K + P Sbjct: 1071 YDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH-------LRPEVLQKM 1123 Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL--EEDGTYTLLILEAYP 4578 +V G K+ ++ W K+ R KI +E+ +Y L I + Sbjct: 1124 DDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKL 1183 Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638 D+G +C A N+AG+ A+ + + N P V EG+ Sbjct: 1184 DDAGTVKCSATNAAGKTVVRADL-------------EVEEKNVAPSFHGRQGRLRVKEGR 1230 Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLI-KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697 +I GKP P+V WYK D +I + + Y I +A PED+G YKC A Sbjct: 1231 EASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEA 1290 Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756 N G + V + P + L+ V EG + +++ +PT++WL+ Sbjct: 1291 RNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEWLK 1350 Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 L+ + F+ +G L I N D + AG+V +SAKL V K Sbjct: 1351 NNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK 1407 Score = 133 bits (322), Expect = 3e-30 Identities = 100/384 (26%), Positives = 163/384 (42%), Gaps = 19/384 (4%) Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477 Q V E ++ +V +P + WY++ ++++ I + L+I ED Sbjct: 3595 QELNVPEGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPED 3654 Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537 S ++ + GT+ + ++ K G V P F +++V G +L K+ Sbjct: 3655 SGLYKCEGVSTLGTSSKTFDV----KAGVPDGSRVTPKFLSHLNSLDVDEGDSAKLTCKM 3710 Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 G V W K+ + + + R + T TL+ QD G Y C A N G Sbjct: 3711 FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSS 3770 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 A VV+ A+ P IIE +D +G +F+ ++ G P P V W+ Sbjct: 3771 SAVIVVN-------------RASITPRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWF 3817 Query: 4658 -KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716 + K++ +Y ++SR D Y+L I G YKC+A N AG+VT L VT+ D Sbjct: 3818 HESTKIVSRGRY-EISRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQD 3876 Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776 A + IVV EG + K PT++W ++G L+ T + + G Sbjct: 3877 FAPIVAGSEMPEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYF 3936 Query: 4777 VLLIGNTYEEDTGTFTCRATTAAG 4800 L + T + D+GT+ AT G Sbjct: 3937 NLDLLKTTQADSGTYKFVATNDLG 3960 Score = 133 bits (321), Expect = 4e-30 Identities = 105/411 (25%), Positives = 177/411 (43%), Gaps = 22/411 (5%) Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465 K +KP + +KM+ + E ++A F V+ G P P I+WY I++ ++ K Sbjct: 1407 KCTKPEVL-EKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQK 1465 Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525 L I+ + ++D + +A N G A L V+E+ I L + V Sbjct: 1466 YSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKER---DYAPIFEEKQFLEPLEIQV 1522 Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY-TLLILEAYPQDSGKY 4584 Q V + V G V W KNGK+++ D ++ + GTY TL IL + +D+G Y Sbjct: 1523 R--QPVEVSYHVRGRPKPTVTWWKNGKELR-DGKHVEIRSGGTYHTLYILRSEEEDAGSY 1579 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644 +C+A N G AE + + KPK + P++ L+ + E E +C Sbjct: 1580 KCLARNDVG----SAERLFEVQVEGVKPKEEA------PKLTSQLRSARITESDDFELAC 1629 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 + G P P+ +W K DK +K ++ S + TL D+G Y N+ G Sbjct: 1630 DVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGST 1689 Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764 +A L + + + L ++D E A+F +I + K ++W A I + Sbjct: 1690 YSSANLDIVKSKSKPEI--LETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDG 1747 Query: 4765 PDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + + + + + I + ED GT+ A G+ A+L VK K Sbjct: 1748 GRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798 Score = 133 bits (321), Expect = 4e-30 Identities = 111/431 (25%), Positives = 180/431 (41%), Gaps = 26/431 (6%) Query: 4387 TTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446 T+E E +Q + +E K + P F ++ V E E A F E G P P I+W+ Sbjct: 4431 TSEKETTSQLFDIHIEDVCKSALAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFM 4490 Query: 4447 ENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR 4504 + P+ S D +I T S + L I + ++D+ V+ +A N G+A +A+L V R Sbjct: 4491 NDQPV--SRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCR 4548 Query: 4505 RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE 4564 + P+F + V G +V G + W K+ ++ R I E Sbjct: 4549 -------MKPTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISE 4601 Query: 4565 EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-KPQTKAANAPP 4623 E Y L I DSG Y C+ N+ G+ C ++ VV A + P P+ + A P Sbjct: 4602 EGDLYNLTIENVGRDDSGTYMCILSNAVGKETCRSQLVVE--AEEFAPFFPEDEGQGAVP 4659 Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK-LIKPSKYFQMSRTADEYTLRI 4682 + + +E + G P P V WYK D+ + + + + Y LR Sbjct: 4660 --------VVTRQDSEVELGAVVRGSPKPEVAWYKDDEDVATDADGLDVGSRDNVYFLRF 4711 Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT--QPDQADNLPA-LTPLRDIVVYEGQPAQ 4739 + +D G YKCVA N G ++ L V P++ + P+ + L V EG+ Sbjct: 4712 ARPSVKDGGLYKCVATNEHGEASMLFNLDVEGHVPEEDWSAPSFVIELTPTTVTEGESTA 4771 Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799 + +IT P ++W + + + +G L++ T ED G + C Sbjct: 4772 LEVEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDL 4831 Query: 4800 GQVETSAKLVV 4810 G + A L V Sbjct: 4832 GTASSMADLSV 4842 Score = 132 bits (320), Expect = 5e-30 Identities = 90/382 (23%), Positives = 165/382 (43%), Gaps = 15/382 (3%) Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFA 4482 FE +AR E G P P ++W+ + + + +++ L+I + +ED+ + Sbjct: 3297 FECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYK 3356 Query: 4483 AVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT--AQNVNVTSGQLVRLDTKVTGT 4540 +A N G+ +L V+E+ + P F N +G V + + G Sbjct: 3357 IIATNEHGSTGSVVDLTVKER-------LFGPEFLEEEGVWNKVAKAGGFVNISFTLKGN 3409 Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600 V W ++G + R I + + I +D+G Y C A + G A Sbjct: 3410 PRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRSCT 3469 Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660 + +P+ + + A I + D EG ++F +I G P P V+WY+G Sbjct: 3470 LEIKVPSMGGPEEKKISKAL----IGQGDNDVQAVEGWKVQFQTRITGYPYPHVEWYRGT 3525 Query: 4661 KLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718 + S +++++T ++ Y+L +++ +D G YKC+A NSAG L V A Sbjct: 3526 IKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDVKDKQYA 3585 Query: 4719 DNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778 +P +++ V EGQ I SK + + W ++G L+ +T + G++ L Sbjct: 3586 PEIPGHEDRQELNVPEGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYL 3645 Query: 4779 LIGNTYEEDTGTFTCRATTAAG 4800 +I + ED+G + C + G Sbjct: 3646 VIPSAAPEDSGLYKCEGVSTLG 3667 Score = 132 bits (320), Expect = 5e-30 Identities = 115/424 (27%), Positives = 188/424 (44%), Gaps = 31/424 (7%) Query: 4401 VEG--PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ 4458 VEG P + P F ++ P V E E EVE G PLP ++W++ + P+K+ + Sbjct: 4741 VEGHVPEEDWSAPSFVIELTPTTVTEGESTALEVEITGTPLPKVEWFKNDKPVKHDHLVR 4800 Query: 4459 IHTFSTKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT 4517 + F K I LI+R+ +ED+ ++ N GTA A+L V + P Sbjct: 4801 SY-FDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNR-------ALTKPEVA 4852 Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577 +++ G VRL+ G V W ++ ++ + R I E + T TL+I Sbjct: 4853 EKMTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCT 4912 Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637 D+G Y+ + N G V++L + + P+ + E ++ ++ + VA Sbjct: 4913 TNDTGPYKVIGTNECG----IGGAVLNLIIHEREFGPE--FIDEEGEYVKVVRSEGVAN- 4965 Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697 I F+ + G P P V WYK L+ + D + L I ED G Y C A Sbjct: 4966 --ITFTVR--GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEA 5021 Query: 4698 YNSAGRVTVAAKLKV--TQPDQADN----LPALT-PLRDIVVYEGQPAQFKTQITSKIKP 4750 + G+ + L V ++ D+ P +T +RD EG +F+ + S P Sbjct: 5022 RSKLGKCFRSCILDVQAVPKEEVDHGQIVKPVITRKIRDAQGEEGSNIRFEIHVKSHPPP 5081 Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809 ++W R + P +Q I EG+ A L I ++DTG++ AT AG + A++V Sbjct: 5082 HVEWYRGSIKLAHGPKYQ-ISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVV 5140 Query: 4810 VKSK 4813 VK K Sbjct: 5141 VKDK 5144 Score = 130 bits (315), Expect = 2e-29 Identities = 102/344 (29%), Positives = 151/344 (43%), Gaps = 23/344 (6%) Query: 4389 EIEHKAQTQERVVEGPVK-PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447 E ++K T R + VK K P T +++P +V E EQ +F G+P P+I WY++ Sbjct: 162 EAKNKIGTSARDFDVNVKVKGKAPTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKD 221 Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507 PIK + T S L+I+ V +D + N G+ +A+L V K + Sbjct: 222 GQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAK- 280 Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED- 4566 P +NV G + K G W + KK++P R KI +D Sbjct: 281 ------PEVVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKKIEPSSRFKITTDDT 334 Query: 4567 -GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625 T +L+I + DSG Y+C+A N AGE A+ V K+KP A Sbjct: 335 EQTSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV-----KNKP----FAPEFADGD 385 Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685 +EP++ V E QA+ + G P P V WYK + +K ++ T D + L I +A Sbjct: 386 LEPIE---VKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKA 442 Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLR 4728 DEG Y C A N G K+ V A + + L PL+ Sbjct: 443 STNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQ 486 Score = 130 bits (315), Expect = 2e-29 Identities = 100/419 (23%), Positives = 180/419 (42%), Gaps = 27/419 (6%) Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 VEG + P T +++ R+ E + + G P P +W +++ P+K Sbjct: 1598 VEGVKPKEEAPKLTSQLRSARITESDDFELACDVKGTPDPSYEWLKDDKPVKFDRHLSSS 1657 Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRRQGRGGIVPPSFTLT 4519 K L ++V + D + +N G+ SANL +V+ K + P T Sbjct: 1658 FDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSK--------PEILET 1709 Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL--EEDGTYTLLILEAY 4577 ++ + D K+ +V W ++ R + EEDGTY++ I + Sbjct: 1710 MKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLR 1769 Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDK-PKPQTKAANAPPEIIEPLKDKIVAE 4636 +D G Y+ VA N G+ AE V K+K P+ + E P + K E Sbjct: 1770 LEDCGTYKIVAFNDIGKTSERAELTV-----KEKLIAPEFEGR----ETEVPFRAK---E 1817 Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 +E S I GKP P V WY+ D+L+ + ++ + + Y + D G Y+C Sbjct: 1818 KSDLEVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCE 1877 Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755 A N G T +++ P D P+ T L+ I V EG+ F ++ ++ +P++ W Sbjct: 1878 AKNRVGSATRNFNVEIEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWY 1937 Query: 4756 R-EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 R + ++P+ + +G L++ + +D G + C A+ G+ +A++ V + Sbjct: 1938 RNKNEIVPDGRS-RTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995 Score = 130 bits (315), Expect = 2e-29 Identities = 91/346 (26%), Positives = 151/346 (43%), Gaps = 21/346 (6%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P+ + + V E A EV+ G P+P ++WY + + + FQ+ L I Sbjct: 1999 PVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSI 2058 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 R V + +A + VA N G A+LV+ E+ P + + V GQ Sbjct: 2059 RDVGDQAAASYKCVAFNNAGRTTYRADLVITERE------YAPEFEDFDEKRIAVREGQN 2112 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 + + DV W K + D + + G Y L I +A D+G Y C A N Sbjct: 2113 AITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATN 2172 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650 S G +V + A K+ P + L+ V EG + + CK+ G P Sbjct: 2173 SIGST--SRRIIVDVEALKEAPV-----------FVSKLRPLFVTEGDNVSWMCKVAGMP 2219 Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710 PTV+WY+ ++ ++ ++M +L +SEA +D+G Y CV NSAG +A+L Sbjct: 2220 RPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAEL 2279 Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756 +V + +A+ + + D+ EG A+F + + +P + W R Sbjct: 2280 QVDK--KANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYR 2323 Score = 130 bits (315), Expect = 2e-29 Identities = 106/414 (25%), Positives = 175/414 (42%), Gaps = 28/414 (6%) Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464 V+ KP T KM E + + + G P+P+++W+R I + ++ Sbjct: 4253 VQACKPQ--TSKMANVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMED 4310 Query: 4465 KSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK---RRQGRGGIVPPSFTLT 4519 + + LII V +EDS + AVA N G A A L V+ K R GG Sbjct: 4311 EGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTVKGKHFARELEEGG--------C 4362 Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579 + GQ+V + + P V W K+G +++ R + Y +++ A + Sbjct: 4363 HSRLTFRKGQMVSVKA-IVPAHPKQVIWYKDGIRLEDSRRVNLRSVGERYYVVVPSASFE 4421 Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 DSG Y+C S E + K P K+A L+ V E ++ Sbjct: 4422 DSGIYKC-ETTSEKETTSQLFDIHIEDVCKSALAPGFKSA---------LRSLDVTEDES 4471 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 EF C++ G P P +QW+ D+ + S + L I++A +D G YKC+A N Sbjct: 4472 AEFRCEVSGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVN 4531 Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759 G T A L V+ + LR++ G A F ++ +P I W ++ Sbjct: 4532 DNGSATSTADLNVSHCRMKPTF--VERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDIT 4589 Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + F + EG+ L I N +D+GT+ C + A G+ ++LVV+++ Sbjct: 4590 RLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAE 4643 Score = 129 bits (311), Expect = 6e-29 Identities = 112/486 (23%), Positives = 198/486 (40%), Gaps = 42/486 (8%) Query: 91 FEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARN 150 FE ++G P P+V W R + + ++++ +E+ SL+I + D G Y C A N Sbjct: 552 FEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASN 611 Query: 151 QYGE--AICSVYIQPEGXXXXXXXXXXXXXYRHVSE-TVEHKAYGTQGYTTEQSRQTQKV 207 G+ A+ ++ + + +H E T + G + + Sbjct: 612 DAGKTTALLNLDVNEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDLVPL 671 Query: 208 AYTNGTDHSST-DDFKVDTFEYRLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPVSP 265 T S D+ ++ E ++ E+ K I ++ G Sbjct: 672 LETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVKVAEPQGET-- 729 Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P I + + + +G D + ++G P P V WFK+G+ L +++ L Sbjct: 730 PTITTEMTDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSF 789 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 R + D G Y C++++ + +V S E +++ Sbjct: 790 RPIKLEDMGRYK--------CVISNVFGSVSSAAE----------------------VKV 819 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 +++L P+ + +D D E + F C +G+P PE+ WF I + V E Sbjct: 820 EDRSLKPEVITSMRDCDCVEEETASFHCEFSGKPEPEIEWFCGPNPIVP--GGRFHVTEE 877 Query: 446 GN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504 GN +L I+++ L D+G CVA N +G+T + L V EK AP+F + T++ + Sbjct: 878 GNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEKH--FAPEFEDWKDTIDALD 935 Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 G+ V ++ G P P I W KDG + ++I G L + + DA Y C Sbjct: 936 GQDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCR 995 Query: 565 AQNVAG 570 A+N AG Sbjct: 996 AKNNAG 1001 Score = 129 bits (311), Expect = 6e-29 Identities = 114/503 (22%), Positives = 211/503 (41%), Gaps = 41/503 (8%) Query: 76 QIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQ 135 Q + R +GG A F K+ P P + W + + ++ ++ +++ L I Sbjct: 1121 QKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDD 1180 Query: 136 IGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQG 195 + D G C+A N G+ + ++ E R V E E Y Sbjct: 1181 VKLDDAGTVKCSATNAAGKTVVRADLEVEEKNVAPSFHGRQGRLR-VKEGREASVYFEIS 1239 Query: 196 YTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTE 255 + S K G + + D + + Y +++ + T + +DV + E Sbjct: 1240 GKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFE 1299 Query: 256 -----IDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310 ++ + P+I Q+ + + EG D + ++SG P P + W KN Sbjct: 1300 TFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEWLKN-------- 1351 Query: 311 KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370 +E+++ ++ R D TL N VT LA P + V++ Sbjct: 1352 -NELLSDNDRFKTRF------DGQTGTLTIRN-----VT---LADAVPYKVVVRN----- 1391 Query: 371 ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430 D + + ++++ K P+ ++ +D EG F+ +++G P P++ W+ Sbjct: 1392 --DAGEVSSSAKLKVIRKCTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTT 1449 Query: 431 QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490 +IRD +K ++ ++L I ++ L D G C+A N++G+ + L V KE+ A Sbjct: 1450 RIRDGGRYKFSRDDQ-KYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEV--KERDYA 1506 Query: 491 PKFVER--FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548 P F E+ L ++ +PV ++ G P P +TW K+G + + I + G TL Sbjct: 1507 PIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTL 1566 Query: 549 DIPRAKASDAAWYQCTAQNVAGS 571 I R++ DA Y+C A+N GS Sbjct: 1567 YILRSEEEDAGSYKCLARNDVGS 1589 Score = 128 bits (309), Expect = 1e-28 Identities = 107/390 (27%), Positives = 158/390 (40%), Gaps = 20/390 (5%) Query: 4427 QARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAE 4486 +ARFEV P P I WY++ +++ + + LII++V + DS + VA Sbjct: 5361 EARFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVAS 5420 Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPID 4544 N+ G L V EK V P F T + V G+ V L T V G Sbjct: 5421 NKAGKTTFLGYLEVMEKT-------VAPEFPDRETLEQVVGVEGREVELSTVVKGLPRPS 5473 Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604 V W K GK + + T+ + I A + SG+Y C A NS G A D V++ Sbjct: 5474 VKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEATNSNGTAHRD--FVLN 5531 Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664 + A P Q A P PL+ + EG F +I G P+P V+WY+ D+ + Sbjct: 5532 IQA--QVPAEQWVA----PAFTAPLQHIDILEGDTTRFIGEITGVPVPVVEWYRDDRPVT 5585 Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724 + L + + D G +KCV N G V +A L V + + Sbjct: 5586 RDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNEGYSKPEIN-- 5643 Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF-QMIHEGNNAVLLIGNT 4783 L+ I +EG A+F +T P + W R I + + + A L I Sbjct: 5644 EKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKI 5703 Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 +ED G + C A G+ + L V K Sbjct: 5704 RQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733 Score = 124 bits (300), Expect = 1e-27 Identities = 121/505 (23%), Positives = 208/505 (41%), Gaps = 42/505 (8%) Query: 82 RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDE 141 R +G A ++ G P P V+W + + + ++ Y+ + IKQ P D+ Sbjct: 1225 RVKEGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSS-YYFTIKQARPEDK 1283 Query: 142 GEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGT---QGYTT 198 G Y C ARN G A + I E + T T GY Sbjct: 1284 GTYKCEARNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPE 1343 Query: 199 EQSRQTQKVAYTNGTDHSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDV-QISTEI 256 + + D T D + T +R V+ +++ + V +D ++S+ Sbjct: 1344 PTLEWLKNNELLSDNDRFKTRFDGQTGTLT---IRNVTLADAVPYKVVVRNDAGEVSSSA 1400 Query: 257 D-RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEII 315 + + + P++ +K ++ K EG +A F V+LSG P P + W+ R+ + +++ Sbjct: 1401 KLKVIRKCTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFS 1460 Query: 316 TTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQ 375 +L +++ D G Y +A N G + QR++ + + Sbjct: 1461 RDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVT-----------------QRAEL--EVK 1501 Query: 376 QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435 +R+ E ++ L P ++V Q +V+ V GRP P VTW+ N +++RD Sbjct: 1502 ERDYAPIFE-EKQFLEPLEIQVRQPVEVSY--------HVRGRPKPTVTWWKNGKELRDG 1552 Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQVVAPKF 493 H + + H L I D+G C+ARN G E F+ ++ ++ ++ APK Sbjct: 1553 -KHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVEGVKPKEE-APKL 1610 Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553 + + + E + L GTP P W KD P+ + L DG TL+ R Sbjct: 1611 TSQLRSARITESDDFELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRV 1670 Query: 554 KASDAAWYQCTAQNVAGSTATRARL 578 + SD Y T +N GST + A L Sbjct: 1671 QLSDQGSYTVTFKNAHGSTYSSANL 1695 Score = 124 bits (300), Expect = 1e-27 Identities = 100/389 (25%), Positives = 166/389 (42%), Gaps = 26/389 (6%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P P + WY++ + ++ + + I V ED+ + A NR G++ S Sbjct: 2654 GNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRS 2713 Query: 4496 ANLVVEEKRR------QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549 + ++E + + G ++P + V G R D V + ID+ W + Sbjct: 2714 CTIEIKEPKSVDSTDTRAPGQLIPVKHKFDFEGV---PGGKARCDVLVKKSDIIDIEWFR 2770 Query: 4550 NGKKVQPDIRNKILEEDGTYTL-LILE-AYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607 ++ + KIL+ D TL LI+E +D+G Y CV AG+ E + Sbjct: 2771 GTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHI---- 2826 Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDK--IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665 K K Q AP + E + + + +GQ + S + G P P + WYK + + Sbjct: 2827 ---KEKQQ-----APLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDD 2878 Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725 ++ + + Y L I PED G Y C A N G + ++ VT P P+ + Sbjct: 2879 TRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPKVKGEAPSFS 2938 Query: 4726 -PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784 LR I E ++ ++ K KP I+W + G + + ++G A L I Sbjct: 2939 LELRPIAAIEEFDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIVAYLSIWQVS 2998 Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 +D GT+ C A+ AAG V +SA L V + Sbjct: 2999 HDDAGTYECIASNAAGTVSSSAALTVSRR 3027 Score = 124 bits (300), Expect = 1e-27 Identities = 121/497 (24%), Positives = 193/497 (38%), Gaps = 29/497 (5%) Query: 4316 KSMAQRYEDNLDQTEEVT--EQR--VQKKVTQKPRIP-DPSESTVHGKEVHVAKQKQTQK 4370 K+ R DN+ + E R V K T KP+I E T+ ++ + K++ Sbjct: 5341 KTQRPRLSDNMKELFATVGGEARFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIY 5400 Query: 4371 EVVGDKEITRKITSTETTEIEHKAQTQE-----RVVEGPVKPSKPPIFTKKMQPCRVFEH 4425 ++ KE+ + T +KA V+E V P P T ++ E Sbjct: 5401 TLI-IKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKTVAPEFPDRET--LEQVVGVEG 5457 Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485 + G P P +KWY+E + S + T + I E S + A Sbjct: 5458 REVELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEA 5517 Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545 N GTA + V+ + + V P+FT Q++++ G R ++TG V Sbjct: 5518 TNSNGTAH--RDFVLNIQAQVPAEQWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVPVV 5575 Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605 W ++ + V D R + + LL+ + D+G ++CV N G A V+ Sbjct: 5576 EWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNE 5635 Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665 +K PEI E LK EG F + G P P V WY+G I Sbjct: 5636 GYSK-------------PEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITD 5682 Query: 4666 SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724 + + T+D +L I + ED G Y CVA N G T L V + Sbjct: 5683 CNRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEKHYGPEFAEE 5742 Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784 +G+ A+ ++ +P + W ++G L+ +T M G+ L I Sbjct: 5743 ELDWSKTARKGENARITFTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLT 5802 Query: 4785 EEDTGTFTCRATTAAGQ 4801 +DTGT+ C A + G+ Sbjct: 5803 HDDTGTYVCEAQSRLGK 5819 Score = 124 bits (298), Expect = 2e-27 Identities = 124/506 (24%), Positives = 202/506 (39%), Gaps = 49/506 (9%) Query: 87 GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146 G A + GNP P V W + L E ++ MR + +++ + P D G Y C Sbjct: 4168 GFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIF--GLTPDDAGTYVC 4225 Query: 147 TARNQYGEAI--CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204 AR++ G C++ ++ ++ + + Q T Sbjct: 4226 EARSRLGTCFRSCTLDVKAVRPRRGNEVQACKPQTSKMANVTAVEGWKVQLDTRMTGYPV 4285 Query: 205 QKVAYTNGTDHSSTDD--FKVDTFE----YRLL-REVSFRESITKRYVGESDVQISTEID 257 V + G + TD +K E Y L+ +V +S + R V +++ +T + Sbjct: 4286 PIVEWFRG-EEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLA 4344 Query: 258 RSL--GPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE 313 G ++ + +S+L ++G + + +P+ +V W+K+G RL +S + Sbjct: 4345 ELTVKGKHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHPK-QVIWYKDGIRLEDSRRVN 4403 Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373 + + + V + DSG Y C TS E T S + D + Sbjct: 4404 LRSVGERYYVVVPSASFEDSGIYK--------CETTS-----EKETTSQLFDIHIE---- 4446 Query: 374 TQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR 433 ++ + ALAP F + DVTE + F C V+G P P + WF+ND+ + Sbjct: 4447 ----------DVCKSALAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFMNDQPVS 4496 Query: 434 DDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPK 492 D +I+ + G H L IT TL D+GV C+A N +G LNV + P Sbjct: 4497 RD--SRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCR--MKPT 4552 Query: 493 FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552 FVER + G + R G P P+I W KD +I I +G L I Sbjct: 4553 FVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYNLTIEN 4612 Query: 553 AKASDAAWYQCTAQNVAGSTATRARL 578 D+ Y C N G R++L Sbjct: 4613 VGRDDSGTYMCILSNAVGKETCRSQL 4638 Score = 121 bits (292), Expect = 1e-26 Identities = 116/510 (22%), Positives = 206/510 (40%), Gaps = 36/510 (7%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P F+ + +GG G++ G P P + W + P++ ++ +++ +T V Sbjct: 2433 PSFKSQLQPVILEEGGTGVLVGEVAGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKV-- 2490 Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191 + ++ GD G Y C +NQ GEA + V Sbjct: 2491 IFREALIGDGGMYECIIKNQCGEASSKALVGVNRGTVGPEIIEKPAGLVIVEGNDSRFDV 2550 Query: 192 GTQGYTTEQSRQTQ-KVAYTNGTDHSSTDDFKVDTFEYRL----LREVSFRESITKRYVG 246 +G+ T + T+G + + ++ + + L + + G Sbjct: 2551 RIRGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTGHYRIVASNEHG 2610 Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKL-QEGADAQFQVQLSGNPRPRVTWFKNGQR 305 ++ + ++ L +P + SK+ ++G L GNPRP VTW+K+G Sbjct: 2611 KAQALLDLTVNERL--YAPEFLEDDGEWSKVVRKGGFVNITFTLMGNPRPFVTWYKDGIL 2668 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365 L ++++ ++ + + + D+G Y A N G S + ++ P Sbjct: 2669 LYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEIKEP------- 2721 Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425 +S TDT R + I + K D + G R D V ++ W Sbjct: 2722 -KSVDSTDT--RAPGQLIPVKHKF----------DFEGVPGGKARCDVLVKKSDIIDIEW 2768 Query: 426 FINDRQIRDDYNHKILVNESGNH-ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484 F +RD +KIL ++ G +L++ NV D+G CV +G+T + L++ E Sbjct: 2769 FRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHIKE 2828 Query: 485 KEQVVAPKFV-ERFS--TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541 K+Q AP F+ E+ S ++ +G+ + + G+PTP ITW KDG P+ + I + Sbjct: 2829 KQQ--APLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRIDIRS 2886 Query: 542 DGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 G L I K DA Y C A N G+ Sbjct: 2887 RGNVYYLGILNLKPEDAGTYTCEAGNRIGA 2916 Score = 121 bits (292), Expect = 1e-26 Identities = 132/531 (24%), Positives = 214/531 (40%), Gaps = 52/531 (9%) Query: 61 ITAGRPGEPSPPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYS 119 I A +P +Q+ +NAR +G KF K+ G P P + WTR + + + Sbjct: 5239 IQAPEAAPKAPAFLKQLLPQNAR--EGDVVKFSCKVTGYPEPEIEWTRDGVSMESDERVT 5296 Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXY 179 Y+ + +S I D G Y CT +N G A S + G Sbjct: 5297 TWYDGEHSTLS--IHNANHADSGMYKCTLKNNSGWASSSAELVVGGKTQRPRLSDNM--- 5351 Query: 180 RHVSETVEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKV---DTFEYRLLREVS 235 + + TV +A + T ++ K+ Y + S D + + D +++EV Sbjct: 5352 KELFATVGGEA---RFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQ 5408 Query: 236 FRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQ-----EGADAQFQVQLS 290 +S T ++V + +T + L + + P L+ EG + + + Sbjct: 5409 LSDSGTYKFVASNKAGKTTFLGY-LEVMEKTVAPEFPDRETLEQVVGVEGREVELSTVVK 5467 Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 G PRP V W+K G +L++++K ++T T HY + P+ S Sbjct: 5468 GLPRPSVKWYKEG-KLLHTSKALTVSTSGDT-------------HYVWI---PSAKHEHS 5510 Query: 351 GYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410 G E+ T S R ++ + Q + +E+ +AP F Q D+ EG TR Sbjct: 5511 GRYRCEA-TNSNGTAHRD-FVLNIQAQVP------AEQWVAPAFTAPLQHIDILEGDTTR 5562 Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT-LSDSGVVTCVARN 469 F +TG P P V W+ +DR + D H++ G +++ T +SD+GV CV RN Sbjct: 5563 FIGEITGVPVPVVEWYRDDRPVTRD--HRLRTYSDGRVVILLLRQTNISDAGVFKCVLRN 5620 Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529 G A LNV E P+ E+ + EG + G P PR+ W + Sbjct: 5621 DLGTVASSASLNV--NEGYSKPEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTT 5678 Query: 530 PIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579 I N T G ++L I + + D Y C A N G T + L+ Sbjct: 5679 KITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLH 5729 Score = 121 bits (291), Expect = 2e-26 Identities = 123/537 (22%), Positives = 211/537 (39%), Gaps = 49/537 (9%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-S 130 P+ +++ K ++GG A E K+ G P P V W +++ +++ + Q GD + Sbjct: 1999 PVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVT---QEGDYHT 2055 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190 L I+ +G Y C A N G + + E Sbjct: 2056 LSIRDVGDQAAASYKCVAFNNAGRTTYRADL-------VITEREYAPEFEDFDEKRIAVR 2108 Query: 191 YGTQGYT--TEQSRQTQKVAYTNGTDHSSTDDFKVDT-----FEYRLLREVSFRESITKR 243 G T T ++R + V + G D D K+D Y +R+ + ++ T Sbjct: 2109 EGQNAITNMTIRARPSPDVEWYKG-DTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGT-- 2165 Query: 244 YVGESDVQISTEIDRSLGPVSP----PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299 Y+ ++ I + R + V P K R + EG + + +++G PRP V W Sbjct: 2166 YICKATNSIGSTSRRIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEW 2225 Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359 +++ Q L + ++ +L + D G Y + N G +S L V+ Sbjct: 2226 YRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKA 2285 Query: 360 ESYVQDQRSQYITDTQQRE-TEERIEISEKALA-PQF------VKVCQDRD--------- 402 + + + + D Q E TE R ++ L P+ +KV ++ Sbjct: 2286 N---KPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEP 2342 Query: 403 --VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460 V E F RV G+P P + W+ + +RD +I + + + + D+ Sbjct: 2343 VVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIR-SRGDIYTFATYSASAEDA 2401 Query: 461 GVVTCVARNKSGETAFQCRLNV-IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519 G TC A NK G+ + L+V + KEQ AP F + + + EG VL G P Sbjct: 2402 GTYTCEASNKLGKCSRDFNLHVDVPKEQWEAPSFKSQLQPVILEEGGTGVLVGEVAGKPL 2461 Query: 520 PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 P I W KD P++ +R DG + A D Y+C +N G +++A Sbjct: 2462 PTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCGEASSKA 2518 Score = 121 bits (291), Expect = 2e-26 Identities = 84/316 (26%), Positives = 136/316 (43%), Gaps = 29/316 (9%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P ++ R G +A F V++ G PRP++ W+K+ RLIN + I + L + Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYNLTI 4610 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 N + DSG Y + N G L VE+ ++ + E + + + Sbjct: 4611 ENVGRDDSGTYMCILSNAVGKETCRSQLVVEA----------EEFAPFFPEDEGQGAVPV 4660 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 + QD +V G + R G P PEV W+ +D + D + + + Sbjct: 4661 VTR----------QDSEVELGAVVR------GSPKPEVAWYKDDEDVATDADGLDVGSRD 4704 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV---IEKEQVVAPKFVERFSTLNV 502 + L ++ D G+ CVA N+ GE + L+V + +E AP FV + V Sbjct: 4705 NVYFLRFARPSVKDGGLYKCVATNEHGEASMLFNLDVEGHVPEEDWSAPSFVIELTPTTV 4764 Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562 EGE L GTP P++ W K+ P+ + +R + DG L + R DA Y+ Sbjct: 4765 TEGESTALEVEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYR 4824 Query: 563 CTAQNVAGSTATRARL 578 CT N G+ ++ A L Sbjct: 4825 CTILNDLGTASSMADL 4840 Score = 120 bits (289), Expect = 3e-26 Identities = 91/345 (26%), Positives = 155/345 (44%), Gaps = 27/345 (7%) Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534 ++D+ + N G+ A++ V++ + V P F ++V + V + Sbjct: 501 LDDAGEYKVKVTNEVGSVTSLADINVQKAK-------VKPEFLRKVEDVTALETEQVWFE 553 Query: 4535 TKVTG-TKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYPQDSGKYECVAINS 4591 + G +PI V W + +++ R I E E+ Y+L+I EA +DSG Y+CVA N Sbjct: 554 IPIQGYPRPI-VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASND 612 Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651 AG+ +++L + +P+ P E V G+ S +I GKP Sbjct: 613 AGKTTA----LLNLDVNEKVVQPEFDKEVKPIE---------VKHGEEATTSLEIKGKPK 659 Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV--TVAAK 4709 P V WYK + ++ Q+ DE+TL I A P+DEG YKC A N AG + K Sbjct: 660 PKVTWYKDLVPLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIK 719 Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769 +KV +P Q + T + DI +G+ + +T + P ++W ++G + Sbjct: 720 VKVAEP-QGETPTITTEMTDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPLKANHRLVP 778 Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 E L ED G + C + G V ++A++ V+ ++ Sbjct: 779 SFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS 823 Score = 120 bits (289), Expect = 3e-26 Identities = 93/379 (24%), Positives = 152/379 (40%), Gaps = 18/379 (4%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIR--QVFVEDSAVFAAVAENRGGTAK 4493 G P P + WY+++ + D + S ++ +R + V+D ++ VA N G A Sbjct: 4676 GSPKPEVAWYKDDEDVATDAD-GLDVGSRDNVYFLRFARPSVKDGGLYKCVATNEHGEAS 4734 Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553 NL VE + PSF + VT G+ L+ ++TGT V W KN K Sbjct: 4735 MLFNLDVEGHVPEEDWSA--PSFVIELTPTTVTEGESTALEVEITGTPLPKVEWFKNDKP 4792 Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613 V+ D + + L++ +D+G Y C +N G A A+ V+ TK Sbjct: 4793 VKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTK---- 4848 Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673 PE+ E + D EG + G P+P V+W++ + + + + +S Sbjct: 4849 ---------PEVAEKMTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISE 4899 Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733 T D TL I D G YK + N G L + + + VV Sbjct: 4900 TEDTSTLVIRNCTTNDTGPYKVIGTNECGIGGAVLNLIIHEREFGPEFIDEEGEYVKVVR 4959 Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793 A + +P + W ++G L+ +T G+ L I + ED GT+ C Sbjct: 4960 SEGVANITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMC 5019 Query: 4794 RATTAAGQVETSAKLVVKS 4812 A + G+ S L V++ Sbjct: 5020 EARSKLGKCFRSCILDVQA 5038 Score = 120 bits (288), Expect = 4e-26 Identities = 101/421 (23%), Positives = 181/421 (42%), Gaps = 22/421 (5%) Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 +E++ K P+ V+ ++ + EG F+ + G P P+ WF + ++I KI Sbjct: 272 LEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKKIEPSSRFKITT 331 Query: 443 NESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER-FSTL 500 +++ +L+I+++ L DSG C+A N++GE + L V K + AP+F + + Sbjct: 332 DDTEQTSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV--KNKPFAPEFADGDLEPI 389 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 V+E + V + G P P +TW KDG + +L++ G L IP+A +D Sbjct: 390 EVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQ 449 Query: 561 YQCTAQNVAGS-------TATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXX 613 Y C A N GS T + Q R V Sbjct: 450 YFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKV 509 Query: 614 YLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673 + + + + + P+F+ ++ VTA+E ++ FE I+ G P +EW Sbjct: 510 KVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPIQ--GYPRPIVEWY 567 Query: 674 KNGQSIEASSRFT--SIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 + I+ RFT SL + +DSG Y C V++ +T A+L++ Sbjct: 568 RGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKC--VASNDAGKTTALLNLDVN 625 Query: 732 ATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFE 791 E+ Q PE + ++ +E + S+E + +P+ + +DL L E R+ + Sbjct: 626 ---EKVVQ-PEFDKEVKPIEVKHGEEATTSLEIKGKPKPK-VTWYKDLVPLLETRSIQLK 680 Query: 792 A 792 + Sbjct: 681 S 681 Score = 119 bits (286), Expect = 7e-26 Identities = 98/428 (22%), Positives = 178/428 (41%), Gaps = 36/428 (8%) Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 V+ P + + P F ++QP + E E G+PLP I+W ++++P+ + Sbjct: 2423 VDVPKEQWEAPSFKSQLQPVILEEGGTGVLVGEVAGKPLPTIQWMKDDYPVLFGHRVRPQ 2482 Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520 +I R+ + D ++ + +N+ G A A + V G V P Sbjct: 2483 FDGRTCKVIFREALIGDGGMYECIIKNQCGEASSKALVGVNR-------GTVGPEIIEKP 2535 Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYP 4578 + + G R D ++ G +V W +++ ++ +I E G Y+L++ + Sbjct: 2536 AGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQL 2595 Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD--KIVAE 4636 +G Y VA N G+A+ + V+ PE +E + K+V + Sbjct: 2596 DQTGHYRIVASNEHGKAQALLDLTVN-------------ERLYAPEFLEDDGEWSKVVRK 2642 Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 G + + ++G P P V WYK L+ + M D I PED G Y C Sbjct: 2643 GGFVNITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCE 2702 Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPA-----LTPLRDIVVYEGQPAQFKTQITSKIKPT 4751 A+N G + +++ +P D+ L P++ +EG P K + +K + Sbjct: 2703 AHNRLGSSFRSCTIEIKEPKSVDSTDTRAPGQLIPVKHKFDFEGVPGG-KARCDVLVKKS 2761 Query: 4752 ----IQWLREGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805 I+W R ++ + ++++ +G L++ N ED GT+ C T AGQ Sbjct: 2762 DIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIR 2821 Query: 4806 AKLVVKSK 4813 +L +K K Sbjct: 2822 GELHIKEK 2829 Score = 119 bits (286), Expect = 7e-26 Identities = 101/395 (25%), Positives = 152/395 (38%), Gaps = 22/395 (5%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F ++++ +A F V G P P I WY++ + N F I L I Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYNLTI 4610 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 V +DS + + N G C + LVVE + P A V Sbjct: 4611 ENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEE---FAPFFPEDEGQGAVPVVTRQDSE 4667 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAI 4589 V L V G+ +V W K+ + V D + D Y L +D G Y+CVA Sbjct: 4668 VELGAVVRGSPKPEVAWYKDDEDVATDADGLDVGSRDNVYFLRFARPSVKDGGLYKCVAT 4727 Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649 N GE A + +L P+ +AP +IE L V EG++ +I G Sbjct: 4728 NEHGE----ASMLFNLDVEGHVPEEDW---SAPSFVIE-LTPTTVTEGESTALEVEITGT 4779 Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709 PLP V+W+K DK +K + L + ED G Y+C N G + A Sbjct: 4780 PLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMAD 4839 Query: 4710 LKV----TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765 L V T+P+ A+ + DI EG + + P ++W R+ + Sbjct: 4840 LSVNRALTKPEVAEK------MTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNND 4893 Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 + + + + L+I N DTG + T G Sbjct: 4894 RYTISETEDTSTLVIRNCTTNDTGPYKVIGTNECG 4928 Score = 118 bits (284), Expect = 1e-25 Identities = 89/325 (27%), Positives = 143/325 (44%), Gaps = 36/325 (11%) Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308 DV I+ E + G P K ++ EG D Q ++G P+P V WF++ + Sbjct: 1006 DVTITVEALQKKGDT--PTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKP 1063 Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368 S + + N + L V+ + D G Y C+VT+ + +V S + Sbjct: 1064 SRRFKASYDGNVSALTVKEAELDDDGVYK--------CVVTNNFGSVSSKAD-------- 1107 Query: 369 QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428 + + +K L P+ ++ D EG F ++ P PE+ W++ Sbjct: 1108 --------------VTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLG 1153 Query: 429 DRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487 +I D KI + E+ ++ L I +V L D+G V C A N +G+T + L V EK Sbjct: 1154 ATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKN- 1212 Query: 488 VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTDGGAS 546 VAP F R L V+EG + G P P +TW KD V I + + I++ G + Sbjct: 1213 -VAPSFHGRQGRLRVKEGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSY 1271 Query: 547 TLDIPRAKASDAAWYQCTAQNVAGS 571 I +A+ D Y+C A+N G+ Sbjct: 1272 YFTIKQARPEDKGTYKCEARNDVGT 1296 Score = 118 bits (283), Expect = 2e-25 Identities = 121/491 (24%), Positives = 191/491 (38%), Gaps = 49/491 (9%) Query: 4250 RPELKPKVIKEPETEW-QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDK 4308 R E+ K +P+ W + + + + Y K ++ +IKE +L +S + +K Sbjct: 5363 RFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVASNK 5422 Query: 4309 VTSNT-------VAKSMAQRYEDN--LDQTEEVTEQRVQKKVTQKPRIPDPSESTV-HGK 4358 T + K++A + D L+Q V + V+ K +P PS GK Sbjct: 5423 AGKTTFLGYLEVMEKTVAPEFPDRETLEQVVGVEGREVELSTVVKG-LPRPSVKWYKEGK 5481 Query: 4359 EVHVAKQKQTQKEVVGDKEIT------------RKITSTETTEIEHKAQTQERVVEGPVK 4406 +H +K GD + +T + H+ + P + Sbjct: 5482 LLHTSKALTVSTS--GDTHYVWIPSAKHEHSGRYRCEATNSNGTAHRDFVLNIQAQVPAE 5539 Query: 4407 PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS 4466 P FT +Q + E + RF E G P+P+++WYR++ P+ + ++ Sbjct: 5540 QWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVV 5599 Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526 IL++RQ + D+ VF V N GT SA+L V E G P + + Sbjct: 5600 ILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNE-------GYSKPEINEKLKKIEAF 5652 Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIR-NKILEEDGTYTLLILEAYPQDSGKYE 4585 G R D VTG P V W + K+ R + L DG +L I + +D G Y Sbjct: 5653 EGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYG 5712 Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD--KIVAEGQAIEFS 4643 CVA+N GE +V L + PE E D K +G+ + Sbjct: 5713 CVAVNEYGE----TTSIVDL---------HVGEKHYGPEFAEEELDWSKTARKGENARIT 5759 Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 + G P P V WYK L+ + + M D L I +D G Y C A + G+ Sbjct: 5760 FTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCEAQSRLGK 5819 Query: 4704 VTVAAKLKVTQ 4714 LKV + Sbjct: 5820 SFRTYALKVEE 5830 Score = 116 bits (279), Expect = 5e-25 Identities = 99/396 (25%), Positives = 158/396 (39%), Gaps = 19/396 (4%) Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477 +P V E + F+V G+P+P I WY++ +++ F+I + ED Sbjct: 2341 EPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAED 2400 Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537 + + A N+ G NL V+ + Q PSF Q V + G L +V Sbjct: 2401 AGTYTCEASNKLGKCSRDFNLHVDVPKEQWEA----PSFKSQLQPVILEEGGTGVLVGEV 2456 Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 G + W+K+ V R + + T ++ EA D G YEC+ N GEA Sbjct: 2457 AGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCGEA-- 2514 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 ++ +V + PEIIE ++ EG F +I G P P V+W+ Sbjct: 2515 SSKALVGV-----------NRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWF 2563 Query: 4658 KG-DKLIKPSKY-FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715 G ++L KY + + Y+L +S+ + G Y+ VA N G+ L V + Sbjct: 2564 YGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER 2623 Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775 A VV +G + +P + W ++G L+ +T M G+ Sbjct: 2624 LYAPEFLEDDGEWSKVVRKGGFVNITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDI 2683 Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 I EDTGT+ C A G S + +K Sbjct: 2684 QYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEIK 2719 Score = 116 bits (279), Expect = 5e-25 Identities = 117/514 (22%), Positives = 209/514 (40%), Gaps = 59/514 (11%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G + E G P P V W R L ++Y++ E T +L+I+ D G Y Sbjct: 4862 EGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTS--TLVIRNCTTNDTGPY 4919 Query: 145 TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204 N+ G + + Y V V + +T + + Sbjct: 4920 KVIGTNECGIGGAVLNLIIHEREFGPEFIDEEGEYVKV---VRSEGVANITFTVRGNPRP 4976 Query: 205 QKVAYTNGTDHSSTDDFKVDTF---EYRLLREVSFRESITKRYVGES------------- 248 + + Y +GT S T ++DT + L S Y+ E+ Sbjct: 4977 EVIWYKDGTLLSDTT--RMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCIL 5034 Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308 DVQ + + G + P I +K R+++ +EG++ +F++ + +P P V W++ +L + Sbjct: 5035 DVQAVPKEEVDHGQIVKPVITRKIRDAQGEEGSNIRFEIHVKSHPPPHVEWYRGSIKLAH 5094 Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368 K++I +L + QK D T SY + Sbjct: 5095 GPKYQISEGDGAYSLTITGVQKDD--------------------------TGSYKVVATN 5128 Query: 369 QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWF 426 Q + T + E + + +K LAP+ ++ +T G + + G+P P V W+ Sbjct: 5129 QAGSSTSRAE----VVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIRGKPKPSVVWY 5184 Query: 427 INDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVVTCVARNKSGETAFQCRLNVIEK 485 + +I N + + G+ +I T S+ +G +C A +K G T+ + + + Sbjct: 5185 KDGNKILTSRN--VQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAKFDVQIQAP 5242 Query: 486 EQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544 E AP F+++ N REG+ V + + G P P I W +DGV + + + DG Sbjct: 5243 EAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGYPEPEIEWTRDGVSMESDERVTTWYDGE 5302 Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 STL I A +D+ Y+CT +N +G ++ A L Sbjct: 5303 HSTLSIHNANHADSGMYKCTLKNNSGWASSSAEL 5336 Score = 115 bits (277), Expect = 8e-25 Identities = 86/302 (28%), Positives = 135/302 (44%), Gaps = 35/302 (11%) Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN-HTTLRVRNTQKSDSGHYT 337 E +A+F V + G P+P V W++ ++ +S KH+I+ + +L +++ K D+G Y Sbjct: 4 ESGEARFDVTIEGYPKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYK 63 Query: 338 LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397 C+ T+ D Q + + EK +APQ + Sbjct: 64 --------CVATN----------------------DAGQTSLRGDLSVKEKQIAPQIKEK 93 Query: 398 CQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456 Q+ +V EG+ D +TG+P PEV W+ + + +R + L + ++ L I T Sbjct: 94 EQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSID-LKSTDDSYFLSIPKAT 152 Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516 +DSG C A+NK G +A +NV K + AP V+EGE G Sbjct: 153 PNDSGKYKCEAKNKIGTSARDFDVNVKVKGK--APTVTSELKPDKVQEGEQYKFTCAVTG 210 Query: 517 TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 P P I+W KDG PI + ++ DG STL I K D Y+ N GS ++ A Sbjct: 211 KPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTA 270 Query: 577 RL 578 L Sbjct: 271 DL 272 Score = 113 bits (273), Expect = 2e-24 Identities = 100/388 (25%), Positives = 161/388 (41%), Gaps = 24/388 (6%) Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447 T + T V + S P +K + + A+F V +G P P + W+ E Sbjct: 3760 TATNQEGSTSSSAVIVVNRASITPRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWFHE 3819 Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG--TAKCSANLVVEEKRR 4505 + I + ++I L+IR V + +A N G TA C ++ ++ Sbjct: 3820 STKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQDFAP 3879 Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565 G +P + + V G V + V G V W K+G+ + + N L Sbjct: 3880 IVAGSEMP-------EPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLS-NTNNLHLRA 3931 Query: 4566 DGTY-TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPE 4624 G Y L +L+ DSG Y+ VA N G A + +L T PK + + P Sbjct: 3932 RGEYFNLDLLKTTQADSGTYKFVATNDLGSAYR----IFNLNVTAIAPKEKWSS----PI 3983 Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684 + L V EG +F + G PLP++QWYK D I + + L I + Sbjct: 3984 FVTELSPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQ 4043 Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQ 4743 ED+G YK V N +G T +AKL V + PA+T L RD+ ++G ++ Q Sbjct: 4044 ITLEDQGQYKVVLKNESGSATSSAKLSVR---EEYGKPAITQLYRDVEGFDGSESELTVQ 4100 Query: 4744 ITSKIKPTIQWLR-EGALIPETPDFQMI 4770 ++ ++W R + L P +++I Sbjct: 4101 VSGVPAAEVEWFRGKTKLFPSERSYKII 4128 Score = 113 bits (272), Expect = 3e-24 Identities = 113/522 (21%), Positives = 212/522 (40%), Gaps = 45/522 (8%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 +P E +P + Q+ ++AR + + + ++G P P W + P+ S ++ Sbjct: 1602 KPKEEAPKLTSQL-RSARITESDDFELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDG 1660 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184 + +L K++ D+G YT T +N +G S + + Sbjct: 1661 KK--CTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSKPEILETMKDAEGIET 1718 Query: 185 TVEHKAYGTQGYTTEQSRQTQKVAYT-NGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243 + Y + + A +G + T D + T+ + ++ + T + Sbjct: 1719 GKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTI-NDLRLEDCGTYK 1777 Query: 244 YVGESDVQISTEI------DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297 V +D+ ++E ++ + P + + P +K E +D + ++G P P V Sbjct: 1778 IVAFNDIGKTSERAELTVKEKLIAPEFEGRETEVPFRAK--EKSDLEVSYNINGKPSPDV 1835 Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 +W+++ + L++ K H + NT + +T+ V++G Sbjct: 1836 SWYRDDRLLLDGRK--------HELRKRGNTYR-----FTVFN-------VSAG------ 1869 Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVT 416 SY + +++ + T+ E IE+ + + AP F + DVTEG+ F CRV Sbjct: 1870 DAGSYRCEAKNRVGSATRNFNVE--IEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVH 1927 Query: 417 GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAF 476 RP P VTW+ N +I D + + + L++ ++ + D+G C+A N G+ Sbjct: 1928 ARPEPSVTWYRNKNEIVPDGRSRTTF-DGETYKLILQDIKIKDAGQYECIASNPIGKAFC 1986 Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536 + V ++E V P E T V EG + + G P P + W ++ Sbjct: 1987 TAEMTVNKRE--VKPVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDR 2044 Query: 537 LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 ++ +G TL I AA Y+C A N AG T RA L Sbjct: 2045 FQVTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADL 2086 Score = 113 bits (272), Expect = 3e-24 Identities = 81/303 (26%), Positives = 138/303 (45%), Gaps = 26/303 (8%) Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N + G L GNPRP V W+++G L ++ + +I + + + + D+ Sbjct: 3391 NKVAKAGGFVNISFTLKGNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDA 3450 Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393 G+Y A + G + S L ++ P+ ++++ IS KAL Q Sbjct: 3451 GNYVCEARSRIGTAIRSCTLEIKVPSMGGPEEKK-----------------IS-KALIGQ 3492 Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL-VNESGNHALMI 452 D EG +F R+TG PYP V W+ ++ D +KI E G ++L++ Sbjct: 3493 GDN---DVQAVEGWKVQFQTRITGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIV 3549 Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV--ERFSTLNVREGEPVVL 510 +VT D G C+A N +G +A CR+N+ K++ AP+ E LNV EG+ + + Sbjct: 3550 NDVTKDDIGTYKCLATNSAGSSA--CRINLDVKDKQYAPEIPGHEDRQELNVPEGQEINM 3607 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 + P ++W KDG + + I + G L IP A D+ Y+C + G Sbjct: 3608 DVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLYKCEGVSTLG 3667 Query: 571 STA 573 +++ Sbjct: 3668 TSS 3670 Score = 113 bits (271), Expect = 4e-24 Identities = 127/516 (24%), Positives = 210/516 (40%), Gaps = 50/516 (9%) Query: 61 ITAGRPGEP-SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYS 119 +TA P E S PIF +G KF + G P P + W + P+ ++ Sbjct: 3970 VTAIAPKEKWSSPIFVTELSPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRIR 4029 Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXY 179 ++ V LLI QI D+G+Y +N+ G A S + Y Sbjct: 4030 TFFDGHV--VKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVR---EEYGKPAITQLY 4084 Query: 180 RHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRES 239 R V +G+ +S T +V+ G + + F+ T + E S++ Sbjct: 4085 RDV-----------EGFDGSESELTVQVS---GVPAAEVEWFRGKTKLFP--SERSYKII 4128 Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL-QEGADAQFQVQLSGNPRPRVT 298 T Y G + I + L P I + + SK+ +E A + GNPRP V Sbjct: 4129 ATNEY-GRTGALIDLTVKERL--FGPEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVF 4185 Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 WFK+G +L +++ ++ + + L + D+G Y A + G S L V++ Sbjct: 4186 WFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKA- 4244 Query: 359 TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418 V+ +R + +A PQ K+ V EG + D R+TG Sbjct: 4245 ----VRPRRGNEV----------------QACKPQTSKMANVTAV-EGWKVQLDTRMTGY 4283 Query: 419 PYPEVTWFINDRQIRDDYNHKIL-VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477 P P V WF + +I D +K + + G ++L+I++V L DSG VA N GE Sbjct: 4284 PVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTL 4343 Query: 478 CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537 L V K + S L R+G+ V + A P ++ W KDG+ + + + Sbjct: 4344 AELTVKGKHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHP-KQVIWYKDGIRLEDSRRV 4402 Query: 538 RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 + + G + +P A D+ Y+C + +T+ Sbjct: 4403 NLRSVGERYYVVVPSASFEDSGIYKCETTSEKETTS 4438 Score = 112 bits (270), Expect = 6e-24 Identities = 96/426 (22%), Positives = 176/426 (41%), Gaps = 23/426 (5%) Query: 4395 QTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS 4454 + + + G + + P +K + E +RF+V G P P ++W+ + + + Sbjct: 2513 EASSKALVGVNRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLTDG 2572 Query: 4455 PDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512 ++I + + L++ +V ++ + + VA N G A+ +L V E+ + Sbjct: 2573 VKYRIESNPEIGLYSLVVSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER-------LY 2625 Query: 4513 PPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570 P F + V G V + + G V W K+G + R + Sbjct: 2626 APEFLEDDGEWSKVVRKGGFVNITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQY 2685 Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 I P+D+G Y C A N G + C + + K T+ AP ++I P+K Sbjct: 2686 CNIFFVGPEDTGTYVCEAHNRLGSS--FRSCTIEIKEPKSVDSTDTR---APGQLI-PVK 2739 Query: 4631 DKIVAEG-QAIEFSCKIVGK--PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR--ISEA 4685 K EG + C ++ K + ++W++G +++ +++ ++ D TL + Sbjct: 2740 HKFDFEGVPGGKARCDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENV 2799 Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD-NLPALTPLRDIVVYEGQPAQFKTQI 4744 ED G Y+CV + AG+ T+ +L + + QA L + +GQ + Sbjct: 2800 CGEDAGTYRCVVHTPAGQTTIRGELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTV 2859 Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804 T P I W ++G + +T + GN L I N ED GT+TC A G Sbjct: 2860 TGSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYR 2919 Query: 4805 SAKLVV 4810 S ++ V Sbjct: 2920 SFEVDV 2925 Score = 109 bits (261), Expect = 7e-23 Identities = 111/515 (21%), Positives = 203/515 (39%), Gaps = 45/515 (8%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P F + +G + + + G P P V W R + + ++ Y+ G+VS Sbjct: 1021 PTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYD---GNVSA 1077 Query: 132 L-IKQIGPGDEGEYTCTARNQYGEA-------ICSVYIQPEGXXXXXXXXXXXXXYRHVS 183 L +K+ D+G Y C N +G + +++PE + + Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPEVLQKMDDVRTVEGGKANFA 1137 Query: 184 ETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243 ++ + ++ T + TD + + + + +L + + S T Sbjct: 1138 VKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCS-YILFIDDVKLDDAGTVKCSATNA 1196 Query: 244 YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303 G++ V+ E++ V+P ++ R +++EG +A ++SG P+P VTW+ Sbjct: 1197 -AGKTVVRADLEVEEK--NVAPSFHGRQGR-LRVKEGREASVYFEISGKPKPSVTWY--- 1249 Query: 304 QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYV 363 K +++ + + + + S ++T+ P +Y Sbjct: 1250 -------KDDVVIGDEDRNVDIYS--RGSSYYFTIKQARPED-------------KGTYK 1287 Query: 364 QDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEV 423 + R+ T + + ++ E +AP+ + Q DVTEG R C+V+G P P + Sbjct: 1288 CEARNDVGTAFETFPIDVEVK-QEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTL 1346 Query: 424 TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483 W N+ + D+ K + L I NVTL+D+ V RN +GE + +L VI Sbjct: 1347 EWLKNNELLSDNDRFKTRF-DGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVI 1405 Query: 484 EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543 K P+ +E+ + EG+ N + G P+P I W I + D Sbjct: 1406 RK--CTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDD 1463 Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 +L I D Y+C A N AG RA L Sbjct: 1464 QKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAEL 1498 Score = 109 bits (261), Expect = 7e-23 Identities = 96/384 (25%), Positives = 166/384 (43%), Gaps = 26/384 (6%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P P + W+++ + + + + + L I + +D+ + A +R GT S Sbjct: 4178 GNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRS 4237 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS--GQLVRLDTKVTGTKPIDVYWLKNGKK 4553 L V+ R + RG V T++ NVT+ G V+LDT++TG V W + +K Sbjct: 4238 CTLDVKAVRPR-RGNEVQACKPQTSKMANVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEK 4296 Query: 4554 VQPDIRNKI--LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611 + R K +E++G Y+L+I + +DSG Y VA N+ GEA AE V Sbjct: 4297 ITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTV-------- 4348 Query: 4612 PKPQTKAANAPPEIIE-PLKDKIV-AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYF 4669 K + E+ E ++ +GQ + + P + WYK ++ S+ Sbjct: 4349 -----KGKHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHPKQVI-WYKDGIRLEDSRRV 4402 Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLR 4728 + + Y + + A ED G YKC + + + + ++ P + LR Sbjct: 4403 NLRSVGERYYVVVPSASFEDSGIYKCETTSEKETTSQLFDIHIEDVCKSALAPGFKSALR 4462 Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEE 4786 + V E + A+F+ +++ P IQW P + D ++I + V L I + Sbjct: 4463 SLDVTEDESAEFRCEVSGSPAPRIQWFMNDQ--PVSRDSRIITSSDGPVHKLAITKATLQ 4520 Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810 DTG + C A G ++A L V Sbjct: 4521 DTGVYKCLAVNDNGSATSTADLNV 4544 Score = 107 bits (258), Expect = 2e-22 Identities = 113/517 (21%), Positives = 204/517 (39%), Gaps = 44/517 (8%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 S P F +G + E ++ G P P V W + P+ + ++ + + Sbjct: 4751 SAPSFVIELTPTTVTEGESTALEVEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKV--I 4808 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET---V 186 L++++ D G Y CT N G A + V T + Sbjct: 4809 RLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAVEGTEVRL 4868 Query: 187 EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG 246 E +G E R V TN ++ ++ T ++R + ++ + +G Sbjct: 4869 EVIKFGCPMPKVEWFR--DNVQLTNNDRYTISETEDTSTL---VIRNCTTNDTGPYKVIG 4923 Query: 247 ESDVQISTEI------DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF 300 ++ I + +R GP + + + + + A+ F V+ GNPRP V W+ Sbjct: 4924 TNECGIGGAVLNLIIHEREFGPEFIDEEGEYVKVVRSEGVANITFTVR--GNPRPEVIWY 4981 Query: 301 KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360 K+G L ++ + + + + L + + D+G Y A + G S L V Sbjct: 4982 KDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCILDV----- 5036 Query: 361 SYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPY 420 Q +E ++ + + P + +D EG RF+ V P Sbjct: 5037 ---------------QAVPKEEVDHGQ-IVKPVITRKIRDAQGEEGSNIRFEIHVKSHPP 5080 Query: 421 PEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480 P V W+ ++ ++I + G ++L IT V D+G VA N++G + R Sbjct: 5081 PHVEWYRGSIKLAHGPKYQISEGD-GAYSLTITGVQKDDTGSYKVVATNQAGSST--SRA 5137 Query: 481 NVIEKEQVVAPKFVERFST--LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538 V+ K++ +APK E +T + + G + LN G P P + W KDG I+ + ++ Sbjct: 5138 EVVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIRGKPKPSVVWYKDGNKILTSRNVQ 5197 Query: 539 IHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575 I + G L I K+ A Y C A + G+T+ + Sbjct: 5198 IRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAK 5234 Score = 107 bits (256), Expect = 3e-22 Identities = 138/683 (20%), Positives = 266/683 (38%), Gaps = 62/683 (9%) Query: 68 EPSPPIFEQIFKNARFA--QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125 + +P ++ +F+ QG + G+PTP ++W + PL + + +R Sbjct: 2830 QQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRIDIR---S 2886 Query: 126 TGDVSLL-IKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184 G+V L I + P D G YTC A N+ G A S + R ++ Sbjct: 2887 RGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPKVKGEAPSFSLELRPIAA 2946 Query: 185 TVEHKAYGTQGYTTEQSRQTQKVAYT-NGTDHSSTDDFKVD---TFEYRLLREVSFRESI 240 E + ++ + ++ +T NG S + D Y + +VS ++ Sbjct: 2947 IEE---FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAG 3003 Query: 241 TKRYVGESDV-QISTEIDRSLGPVSP-PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT 298 T + + +S+ ++ + P I K + K EG +A+F ++++G+P P V Sbjct: 3004 TYECIASNAAGTVSSSAALTVSRRNMRPLITHKLHDMKAYEGKEARFDIEVTGHPSPTVE 3063 Query: 299 WFKNGQRLINSNKHEIITTHNH--TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356 WFK + ++++++ +L V + D G Y +A+N LA + Sbjct: 3064 WFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDGIYKCVAQN----------LAGK 3113 Query: 357 SPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT 416 + T + + + + + E+ + + ++E G+ + V Sbjct: 3114 ASTRAMLDVIARDFGPEFDEEESPKPVIVNE------------------GEEAQMMVSVR 3155 Query: 417 GRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETA 475 GRP V WF + + + D + ++ V GN H L+I +VT D G CVA + +G ++ Sbjct: 3156 GRPKAVVEWFKDGKFLYD--SRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSS 3213 Query: 476 --FQCRLNVIE-KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532 F + V + K++ P F + L EGE G P P + W KD PI Sbjct: 3214 RTFDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIK 3273 Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKR 592 R + DG L + + + + + A +VAG + + R Sbjct: 3274 HEDRFRTYFDGRVCMLVFRKTDSFECSEARLEA-HVAGVPRPTVEWFLGSAKLCDGERYR 3332 Query: 593 LHLPRPTKVXXXXXXXXXXXXYLRHVE-----RARPYIPPGEEDRVYPPPQFIVP--LKS 645 L + + + ++R++ P+F+ + + Sbjct: 3333 LEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKERLF-GPEFLEEEGVWN 3391 Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705 A GG ++ ++ G+P + W ++G + ++R R +++ L ++D Sbjct: 3392 KVAKAGGFVNISFTLK--GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLED 3449 Query: 706 SGEYTCRAVSATGVAETKAVLHV 728 +G Y C A S G A L + Sbjct: 3450 AGNYVCEARSRIGTAIRSCTLEI 3472 Score = 106 bits (255), Expect = 4e-22 Identities = 118/522 (22%), Positives = 210/522 (40%), Gaps = 61/522 (11%) Query: 77 IFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQ 135 +F+ + A+ E + G P P V W A L + +Y + EQT ++ +L+I Sbjct: 3290 VFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRL---EQTDNLYTLVISN 3346 Query: 136 IGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQG 195 + D G Y A N++G V + + + V++ + Sbjct: 3347 LHMEDTGPYKIIATNEHGSTGSVVDLTVKERLFGPEFLEEEGVWNKVAKA---GGFVNIS 3403 Query: 196 YTTEQSRQTQKVAYTNGT---DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQI 252 +T + + + V Y +G D + D Y + ++ ++ YV E+ +I Sbjct: 3404 FTLKGNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDA--GNYVCEARSRI 3461 Query: 253 STEIDRSL---------GP----VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299 T I GP +S I Q + + EG QFQ +++G P P V W Sbjct: 3462 GTAIRSCTLEIKVPSMGGPEEKKISKALIGQGDNDVQAVEGWKVQFQTRITGYPYPHVEW 3521 Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359 ++ +L +S+K++I Q + G Y+L+ V T Sbjct: 3522 YRGTIKLHDSDKYKI-------------AQTKEDGLYSLI---------------VNDVT 3553 Query: 360 ESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV--KVCQDRDVTEGKMTRFDCRVTG 417 + + + +++ +K AP+ + Q+ +V EG+ D + Sbjct: 3554 KDDIGTYKCLATNSAGSSACRINLDVKDKQYAPEIPGHEDRQELNVPEGQEINMDVVIKS 3613 Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGETA- 475 +P EV+W+ + ++D +I + G+H L+I + DSG+ C + G ++ Sbjct: 3614 KPRLEVSWYKDGELLQD--TKRIDIRSRGDHYYLVIPSAAPEDSGLYKCEGVSTLGTSSK 3671 Query: 476 -FQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534 F + V + +V PKF+ ++L+V EG+ L + G P P + W KD I N Sbjct: 3672 TFDVKAGVPDGSRVT-PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQLITNN 3730 Query: 535 PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 +R G TL D Y+CTA N GST++ A Sbjct: 3731 DRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSA 3772 Score = 105 bits (251), Expect = 1e-21 Identities = 82/372 (22%), Positives = 151/372 (40%), Gaps = 22/372 (5%) Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503 WY++ +++S + + + +++ EDS ++ + T ++ +E+ Sbjct: 4389 WYKDGIRLEDSRRVNLRSVGERYYVVVPSASFEDSGIYKCETTSEKETTSQLFDIHIEDV 4448 Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563 + + P F ++++VT + +V+G+ + W N + V D R Sbjct: 4449 CKSA----LAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFMNDQPVSRDSRIITS 4504 Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623 + + L I +A QD+G Y+C+A+N G A A+ VS K P Sbjct: 4505 SDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMK-------------P 4551 Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG-DKLIKPSKYFQMSRTADEYTLRI 4682 +E L++ G FS ++ G P P + WYK +LI + F +S D Y L I Sbjct: 4552 TFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGR-FHISEEGDLYNLTI 4610 Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK- 4741 +D G Y C+ N+ G+ T ++L V + A P + V Q ++ + Sbjct: 4611 ENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEEFAPFFPEDEGQGAVPVVTRQDSEVEL 4670 Query: 4742 -TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL-IGNTYEEDTGTFTCRATTAA 4799 + KP + W ++ + D + +N L +D G + C AT Sbjct: 4671 GAVVRGSPKPEVAWYKDDEDVATDADGLDVGSRDNVYFLRFARPSVKDGGLYKCVATNEH 4730 Query: 4800 GQVETSAKLVVK 4811 G+ L V+ Sbjct: 4731 GEASMLFNLDVE 4742 Score = 103 bits (247), Expect = 4e-21 Identities = 115/510 (22%), Positives = 200/510 (39%), Gaps = 53/510 (10%) Query: 86 GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEY 144 GG L+GNP P V W R L + + +R GD+ + I + D G Y Sbjct: 3397 GGFVNISFTLKGNPRPHVVWYRDGILLYDTTRMDIR---SRGDLHYVNIYGLTLEDAGNY 3453 Query: 145 TCTARNQYGEAI--CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH-KAYGTQGYTTEQS 201 C AR++ G AI C++ I+ V+ + + Q T Sbjct: 3454 VCEARSRIGTAIRSCTLEIKVPSMGGPEEKKISKALIGQGDNDVQAVEGWKVQFQTRITG 3513 Query: 202 RQTQKVAYTNGTDH-SSTDDFKV-DTFE---YRLL------REVSFRESITKRYVGESDV 250 V + GT +D +K+ T E Y L+ ++ + + G S Sbjct: 3514 YPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSAC 3573 Query: 251 QISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309 +I+ ++ D+ P P ++ N + EG + V + PR V+W+K+G+ L ++ Sbjct: 3574 RINLDVKDKQYAPEIPGHEDRQELN--VPEGQEINMDVVIKSKPRLEVSWYKDGELLQDT 3631 Query: 310 NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369 + +I +S HY L+ P+ SG E S Sbjct: 3632 KRIDI---------------RSRGDHYYLVI--PSAAPEDSGLYKCEGV---------ST 3665 Query: 370 YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIND 429 T ++ + + + + + P+F+ DV EG + C++ G+P P V WF +D Sbjct: 3666 LGTSSKTFDVKAGVPDGSR-VTPKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDD 3724 Query: 430 RQIRDDYNHKILVNESGNHALMI-TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488 + I + N ++ + GN +I V + D G C A N+ G T+ + V+ + + Sbjct: 3725 QLITN--NDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVI-VVNRASI 3781 Query: 489 VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548 P+ +E+ ++ +G R G P P++TW + I+ I G +L Sbjct: 3782 T-PRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWFHESTKIVSRGRYEISRVGDLYSL 3840 Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARL 578 I + Y+C A N AG L Sbjct: 3841 VIRGVEYLHVGTYKCIATNDAGKVTAHCHL 3870 Score = 103 bits (246), Expect = 5e-21 Identities = 96/326 (29%), Positives = 145/326 (44%), Gaps = 41/326 (12%) Query: 249 DVQISTEIDRSLGPVSPPKIAQK-PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307 DVQI P +P + Q P+N++ EG +F +++G P P + W ++G + Sbjct: 5236 DVQIQAP---EAAPKAPAFLKQLLPQNAR--EGDVVKFSCKVTGYPEPEIEWTRDGVSME 5290 Query: 308 NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367 + + H+TL + N +DSG Y +N +G +S L V T+ Sbjct: 5291 SDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKTQRPRLSDN 5350 Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427 + + T E R E++ KA P+ K+C +D E+T Sbjct: 5351 MKELFATVGGEA--RFEVTMKA-TPK-PKICWYKD-------------------EIT--- 5384 Query: 428 NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487 + RD Y K E G + L+I V LSDSG VA NK+G+T F L V+EK Sbjct: 5385 --LRSRDRYTMK---EEDGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK-- 5437 Query: 488 VVAPKFVERFSTLNV--REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545 VAP+F +R + V EG V L+ G P P + W K+G + + L + T G Sbjct: 5438 TVAPEFPDRETLEQVVGVEGREVELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDT 5497 Query: 546 STLDIPRAKASDAAWYQCTAQNVAGS 571 + IP AK + Y+C A N G+ Sbjct: 5498 HYVWIPSAKHEHSGRYRCEATNSNGT 5523 Score = 102 bits (244), Expect = 8e-21 Identities = 80/303 (26%), Positives = 124/303 (40%), Gaps = 34/303 (11%) Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338 +G D + G P+P + W K+G+ L N+ +I + L + D+G YT Sbjct: 935 DGQDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTC 994 Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398 A+N G + S+ +T T + + +K P F+ Sbjct: 995 RAKNNAGIV--------------------SKDVTITVEA-------LQKKGDTPTFMSKL 1027 Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTL 457 + ++TEG + C VTGRP PEV WF ++ I+ K + GN AL + L Sbjct: 1028 EPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFK--ASYDGNVSALTVKEAEL 1085 Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517 D GV CV N G + + + V++K + P+ +++ + EG + Sbjct: 1086 DDDGVYKCVVTNNFGSVSSKADVTVLKKH--LRPEVLQKMDDVRTVEGGKANFAVKIDAF 1143 Query: 518 PTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575 P P I W I +I TD + L I K DA +C+A N AG T R Sbjct: 1144 PKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVR 1203 Query: 576 ARL 578 A L Sbjct: 1204 ADL 1206 Score = 98.3 bits (234), Expect = 1e-19 Identities = 52/199 (26%), Positives = 95/199 (47%), Gaps = 2/199 (1%) Query: 379 TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438 T ++++EK AP+F D +G+ V G+P PE+ W + ++R+ + Sbjct: 909 TRAELKVNEKHFAPEFEDWKDTIDALDGQDVNISTWVRGKPKPEIVWLKDGEELRNTMHV 968 Query: 439 KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERF 497 +I H L++ V+ D+G+ TC A+N +G + + V +++ P F+ + Sbjct: 969 QIKCY-GDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEALQKKGDTPTFMSKL 1027 Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557 + + EG+ L+ G P P + W +D V I P+ + DG S L + A+ D Sbjct: 1028 EPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDD 1087 Query: 558 AAWYQCTAQNVAGSTATRA 576 Y+C N GS +++A Sbjct: 1088 DGVYKCVVTNNFGSVSSKA 1106 Score = 97.5 bits (232), Expect = 2e-19 Identities = 68/274 (24%), Positives = 124/274 (45%), Gaps = 11/274 (4%) Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596 V G V+W K+G ++ R + D L I P D+G Y C A + G Sbjct: 4176 VLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGT-- 4233 Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656 C C + + A + + + +A P+ + + + EG ++ ++ G P+P V+W Sbjct: 4234 CFRSCTLDVKAVRPRRGNEVQACK--PQTSK-MANVTAVEGWKVQLDTRMTGYPVPIVEW 4290 Query: 4657 YKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714 ++G++ I ++ +R DE Y+L IS+ ED G Y+ VA N+ G T A+L V Sbjct: 4291 FRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTVKG 4350 Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774 A L + +GQ K + + K I W ++G + ++ + G Sbjct: 4351 KHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHPKQVI-WYKDGIRLEDSRRVNLRSVGE 4409 Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 +++ + ED+G + C T+ + ET+++L Sbjct: 4410 RYYVVVPSASFEDSGIYKCETTS---EKETTSQL 4440 Score = 94.7 bits (225), Expect = 2e-18 Identities = 107/506 (21%), Positives = 184/506 (36%), Gaps = 39/506 (7%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-S 130 P F+ ++ + +A+F ++ G+P P + W P+ ++ S G V Sbjct: 4455 PGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFMNDQPV---SRDSRIITSSDGPVHK 4511 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190 L I + D G Y C A N G A + + V + Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGEASFS 4571 Query: 191 YGTQGYTTEQSRQTQKVA--YTNGTDHSSTD-DFKVDTFEYRLLREVSFRESITKRYVGE 247 +G+ + + + G H S + D T E + I VG+ Sbjct: 4572 VRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGK 4631 Query: 248 SDVQISTEID-RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306 + ++ P P Q ++ ++ + + G+P+P V W+K+ + + Sbjct: 4632 ETCRSQLVVEAEEFAPFFPEDEGQGAVPVVTRQDSEVELGAVVRGSPKPEVAWYKDDEDV 4691 Query: 307 I-NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365 +++ ++ + N LR D G Y +A N +G + E +V + Sbjct: 4692 ATDADGLDVGSRDNVYFLRFARPSVKDGGLYKCVATNEHG----EASMLFNLDVEGHVPE 4747 Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425 E AP FV VTEG+ T + +TG P P+V W Sbjct: 4748 ---------------------EDWSAPSFVIELTPTTVTEGESTALEVEITGTPLPKVEW 4786 Query: 426 FINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484 F ND+ ++ D H + G L++ TL D+G+ C N G + L+V Sbjct: 4787 FKNDKPVKHD--HLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV-- 4842 Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544 + P+ E+ + ++ EG V L G P P++ W +D V + N I Sbjct: 4843 NRALTKPEVAEKMTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISETED 4902 Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAG 570 STL I +D Y+ N G Sbjct: 4903 TSTLVIRNCTTNDTGPYKVIGTNECG 4928 Score = 94.3 bits (224), Expect = 2e-18 Identities = 109/480 (22%), Positives = 179/480 (37%), Gaps = 39/480 (8%) Query: 61 ITAGRP-GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYS 119 + AG P G P F + +G +AK K+ G P P V W + + N Sbjct: 3675 VKAGVPDGSRVTPKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQLIT--NNDR 3732 Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXY 179 +R + +L+ + + D G Y CTA NQ G S I Sbjct: 3733 VRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNRASITPRIIEKPRDV 3792 Query: 180 RHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRES 239 V T +G+ Q + T T + +V ++R V + Sbjct: 3793 DAVDGTDAKFTVRVEGFP--QPKVTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHV 3850 Query: 240 ITKRYVGESD---VQISTEIDRSLGPVSPPKI-AQKPRNSKLQEGADAQFQVQLSGNPRP 295 T + + +D V +D + +P ++ P ++EG + + G P P Sbjct: 3851 GTYKCIATNDAGKVTAHCHLDVTKQDFAPIVAGSEMPEPIVVREGCEVSMMANVRGKPAP 3910 Query: 296 RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 V WFK+GQ +++ N+ LR R + T A++ T ++A Sbjct: 3911 TVEWFKDGQ---------LLSNTNNLHLRARGEYFNLDLLKTTQADSG-----TYKFVAT 3956 Query: 356 ESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRV 415 +Y R + T I EK +P FV VTEG T+F V Sbjct: 3957 NDLGSAY----RIFNLNVTA-------IAPKEKWSSPIFVTELSPLSVTEGDYTKFVAHV 4005 Query: 416 TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGET 474 +G P P + W+ +D I NH+I G+ L+I +TL D G V +N+SG Sbjct: 4006 SGVPLPSIQWYKDDNPISS--NHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSA 4063 Query: 475 AFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534 +L+V +E+ P + + + +G L + G P + W + + P+ Sbjct: 4064 TSSAKLSV--REEYGKPAITQLYRDVEGFDGSESELTVQVSGVPAAEVEWFRGKTKLFPS 4121 Score = 93.5 bits (222), Expect = 4e-18 Identities = 55/193 (28%), Positives = 94/193 (48%), Gaps = 5/193 (2%) Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 + ++ + P+ ++ + EG +RFD R+ G P PEV WF ++ D ++I Sbjct: 2520 VGVNRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLTDGVKYRIES 2579 Query: 443 N-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501 N E G ++L+++ V L +G VA N+ G+ Q L++ E++ AP+F+E + Sbjct: 2580 NPEIGLYSLVVSKVQLDQTGHYRIVASNEHGKA--QALLDLTVNERLYAPEFLEDDGEWS 2637 Query: 502 --VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559 VR+G V + +G P P +TW KDG+ + + + G +I D Sbjct: 2638 KVVRKGGFVNITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTG 2697 Query: 560 WYQCTAQNVAGST 572 Y C A N GS+ Sbjct: 2698 TYVCEAHNRLGSS 2710 Score = 92.7 bits (220), Expect = 7e-18 Identities = 81/310 (26%), Positives = 133/310 (42%), Gaps = 39/310 (12%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 PK + + EG A+ ++ G P P V WFK+ Q LI +N RV Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQ-LITNND------------RV 3733 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER--- 382 R++ ++ TL+ E N +QD+ + T T Q + Sbjct: 3734 RSSVVGNT--CTLIFETVN------------------IQDRGAYRCTATNQEGSTSSSAV 3773 Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 I ++ ++ P+ ++ +D D +G +F RV G P P+VTWF +I ++I Sbjct: 3774 IVVNRASITPRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWFHESTKIVSRGRYEI-- 3831 Query: 443 NESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501 + G+ ++L+I V G C+A N +G+ C L+V +++ E + Sbjct: 3832 SRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQDFAPIVAGSEMPEPIV 3891 Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561 VREG V + A G P P + W KDG + L + G LD+ + +D+ Y Sbjct: 3892 VREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTY 3951 Query: 562 QCTAQNVAGS 571 + A N GS Sbjct: 3952 KFVATNDLGS 3961 Score = 91.1 bits (216), Expect = 2e-17 Identities = 106/470 (22%), Positives = 179/470 (38%), Gaps = 49/470 (10%) Query: 4102 VEESKARCP-PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 +E KAR P F + + V EGE F CRV P+P V W N N IV R + T Sbjct: 1893 IEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWYRNKNEIVPDGRSRTT 1952 Query: 4161 YDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYD 4219 +DG Y + + D G+ E I + V R + + V+K Sbjct: 1953 FDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR--EVKPVIK-------- 2002 Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279 E+ KTFE + G E+K + P EW R + + + Sbjct: 2003 ----------EVSKTFE----VSEGGTASI--EVKVSGVPVPTVEWYHGSNRVLDGDRFQ 2046 Query: 4280 KLQELENEQV-IKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRV- 4337 QE + + I++ + + + + T + + + E+ E+R+ Sbjct: 2047 VTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIA 2106 Query: 4338 ----QKKVTQKP--RIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEIT-RKITSTETTEI 4390 Q +T P P G + ++ +K K + G + RK T + Sbjct: 2107 VREGQNAITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTY 2166 Query: 4391 EHKA-----QTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445 KA T R++ + P+F K++P V E + + + G P P ++WY Sbjct: 2167 ICKATNSIGSTSRRIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWY 2226 Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRR 4505 R+N P++ +++ L + + +D V+ V N G+A SA L V++K Sbjct: 2227 RDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKAN 2286 Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555 + P +V G R D + +G +V W +N KV+ Sbjct: 2287 K-------PKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVR 2329 Score = 90.6 bits (215), Expect = 3e-17 Identities = 57/207 (27%), Positives = 91/207 (43%), Gaps = 6/207 (2%) Query: 374 TQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432 T R + +++++E + P D +G+ + C VTG P PEV WF + + + Sbjct: 711 TAFRSFDIKVKVAEPQGETPTITTEMTDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPL 770 Query: 433 RDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491 + NH+++ + E AL + L D G CV N G + + V +++ + P Sbjct: 771 KA--NHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKV--EDRSLKP 826 Query: 492 KFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551 + + + E E + G P P I W PI+P + +G +L I Sbjct: 827 EVITSMRDCDCVEEETASFHCEFSGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAIS 886 Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578 K DA Y+C A N AG T TRA L Sbjct: 887 DLKLEDAGNYKCVASNAAGKTTTRAEL 913 Score = 90.6 bits (215), Expect = 3e-17 Identities = 64/224 (28%), Positives = 99/224 (44%), Gaps = 6/224 (2%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 VF+S L + EGDN+ + C V PT +EW+ +N+PL + TR+K D SL Sbjct: 2193 VFVSKLRPLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLF 2250 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894 ++ +D G+Y C TNS GSA +S L+ N + +E E + R Sbjct: 2251 LSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVR 2310 Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLH----LEGQVEPKNDPDLKIEWYFN 2950 + RP V + +L E V+ + +V + P I WY + Sbjct: 2311 FSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKD 2370 Query: 2951 GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 G+++ RF++ S T D+G YTC+A NK G+ Sbjct: 2371 GEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGK 2414 Score = 90.2 bits (214), Expect = 4e-17 Identities = 145/604 (24%), Positives = 234/604 (38%), Gaps = 76/604 (12%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV--SLD 2834 + + N+ EG + FE V+ P K EWF ++K + +R+K T D + SL Sbjct: 284 VRKMENVESVEGSDAFFE--VKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLV 341 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894 I+ +DSG Y C A+N G L+ KN F + G LE +E E+ Sbjct: 342 ISDLRLDDSGAYQCIASNEAGECNLRADLKV---KNKPFAPEFADGD--LEPIEVKEDQ- 395 Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIE---WYFNG 2951 A R +V P+ W H + + L G V + P YF Sbjct: 396 -AVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLK-LKATGDVHELSIPKASTNDEGQYFCE 453 Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011 GS K T V + V E SG+ + + G ++ +T + + ++ Sbjct: 454 ASNPLGSP-KRTFKVTVVPKGVAPVIE--SGLMPLQVRKETGAKWSVNTTLDDAGEYKVK 510 Query: 3012 RTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEAS 3071 T L I N++ + K PEF +D+ + Q+ +E Sbjct: 511 VTNEVGSVTSLADI-NVQKAKVK-------------PEFLRKVEDVTALETEQV-WFEIP 555 Query: 3072 LIPTGDQSMVIEWFYNGKTIEASHR--IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKW 3129 + G ++EW+ I+ R I M L I +T DSG Y C A+N Sbjct: 556 I--QGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDA 613 Query: 3130 GQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189 G+ + L+ +K +P F ++ IE +K G+ A + P K+ WY + Sbjct: 614 GKTTALLNLDVNEKVV--QPEFDKEVKPIE-VKHGEEATTSLEIK--GKPKPKVTWYKDL 668 Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYL 3249 P+ + I+ S L+I D G+Y C A NK G F I Sbjct: 669 VPLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIK--------- 719 Query: 3250 ESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPV 3309 K+ E Q +TP+ T++ D+ + ++G+ + Sbjct: 720 --------VKVAE------PQGETPT--------ITTEMTDI-QAIDGEDCKLICHV--T 754 Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTK 3369 +P+ +VEWF +GK L HR + ++ L E+ G Y+CV +N G S+ Sbjct: 755 GEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSA 814 Query: 3370 ANLK 3373 A +K Sbjct: 815 AEVK 818 Score = 90.2 bits (214), Expect = 4e-17 Identities = 66/212 (31%), Positives = 96/212 (45%), Gaps = 7/212 (3%) Query: 372 TDTQQRETEERIEISEKALAPQFV--KVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFIN 428 T Q + I EK AP F+ KV Q++ + +G+ VTG P P +TW+ Sbjct: 2813 TPAGQTTIRGELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWY-K 2871 Query: 429 DRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KE 486 D + DD +I + GN + L I N+ D+G TC A N+ G ++V K Sbjct: 2872 DGEPLDD-TRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPKV 2930 Query: 487 QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546 + AP F + E L G P P+I W K+G P+ + LR DG + Sbjct: 2931 KGEAPSFSLELRPIAAIEEFDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIVA 2990 Query: 547 TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 L I + DA Y+C A N AG+ ++ A L Sbjct: 2991 YLSIWQVSHDDAGTYECIASNAAGTVSSSAAL 3022 Score = 90.2 bits (214), Expect = 4e-17 Identities = 174/745 (23%), Positives = 289/745 (38%), Gaps = 158/745 (21%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G PK VEW ++G + S R+ L + +V PED G+Y C A + G + + Sbjct: 3156 GRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRT 3215 Query: 1798 STLFVQSKASLQLES--QHESALQKIQQLE-DSSRY------QRREDVEVAVNQAP---- 1844 L V+ S S L+ ++ LE + +++ + VE + P Sbjct: 3216 FDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHE 3275 Query: 1845 -RFITQLNGPT-KLSEGQSAHYEC---RIEPYPD--PNMRVEWYFNGKVLQSGHRYRTSN 1897 RF T +G L ++ +EC R+E + P VEW+ L G RYR Sbjct: 3276 DRFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQ 3335 Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQY 1957 L I ++ ED+G Y II ++H S + Sbjct: 3336 TDNLYTLVISNLHMEDTGPY-----------------------KIIATNEHGSTGSVV-- 3370 Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNG 2017 D K + F+ E+ + K K G V++ TL +P V WY +G Sbjct: 3371 ---DLTVKERLFGPEFLEEEGVWNKVAK-----AGGFVNISFTLK--GNPRPHVVWYRDG 3420 Query: 2018 RPVQQGHRF--KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGL 2075 + R ++ D YV +I ED G Y+C+A + +G A+ + ++++ Sbjct: 3421 ILLYDTTRMDIRSRGDLHYV--NIYGLTLEDAGNYVCEARSRIGTAIRSCTLEI------ 3472 Query: 2076 YLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEP 2135 K+ + E K I + GQ + A+ EG + F+ R+ Sbjct: 3473 -----------KVPSMGGPEEKK-ISKALIGQGDNDVQAV-------EGWKVQFQTRITG 3513 Query: 2136 INDPHLTIDWFHNGQKIRAGHRYRT--THDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193 PH ++W+ K+ +Y+ T + G +L + +D GTY C ATN G + Sbjct: 3514 YPYPH--VEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSS 3571 Query: 2194 VNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTH 2253 C + + + D Q+ E GH R E+ P Sbjct: 3572 A--CRINLD-----VKDKQYAP--------EIPGHEDRQELNVP---------------- 3600 Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313 EG+ + + ++ P L + +Y +G+ LQ R I + L I PED+G Sbjct: 3601 --EGQEINMDVVIKS--KPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSG 3656 Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTR 2373 Y + ++ LG TS S T K + P+G +R Sbjct: 3657 LYKCEGVSTLG--TS--SKTFDVKAGV------PDG----------------------SR 3684 Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433 P F L ++D + EG +A C++ +PT VEWF++++LI ++ R+ + Sbjct: 3685 VTPKFLSHLNSLD-VDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNT 3741 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458 ++ V +D G Y C A+N G Sbjct: 3742 CTLIFETVNIQDRGAYRCTATNQEG 3766 Score = 88.6 bits (210), Expect = 1e-16 Identities = 71/293 (24%), Positives = 122/293 (41%), Gaps = 24/293 (8%) Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591 RL+ V G V W K+ R ++ + D YTL+I + +D+G Y+ +A N Sbjct: 3303 RLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNE 3362 Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP--LKDKIVAEGQAIEFSCKIVGK 4649 G + V K PE +E + +K+ G + S + G Sbjct: 3363 HGSTGSVVDLTV-------------KERLFGPEFLEEEGVWNKVAKAGGFVNISFTLKGN 3409 Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709 P P V WY+ L+ + + D + + I ED G+Y C A + G + Sbjct: 3410 PRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRSCT 3469 Query: 4710 LKVTQP-----DQADNLPALTPL--RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 L++ P ++ AL D+ EG QF+T+IT P ++W R + Sbjct: 3470 LEIKVPSMGGPEEKKISKALIGQGDNDVQAVEGWKVQFQTRITGYPYPHVEWYRGTIKLH 3529 Query: 4763 ETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 ++ +++ + + L++ + ++D GT+ C AT +AG L VK K Sbjct: 3530 DSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDVKDK 3582 Score = 87.8 bits (208), Expect = 2e-16 Identities = 110/515 (21%), Positives = 187/515 (36%), Gaps = 44/515 (8%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P Q + +G + + K+ G P P + W + L + +++ R++ QTG +L Sbjct: 1315 PEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEWLKNNELLSDNDRFKTRFDGQTG--TL 1372 Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVS---ETVEH 188 I+ + D Y RN GE S ++ + V T Sbjct: 1373 TIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDVKGVEGDEATFNV 1432 Query: 189 KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVD-TFEYRLLREVSFRESITKRYVGE 247 K G E T ++ G S DD K T + L+++ + I G+ Sbjct: 1433 KLSGYPSPDIEWYYGTTRIR-DGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGK 1491 Query: 248 SDVQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306 + E+ +R P+ K +P ++++ + + V+ G P+P VTW+KNG+ L Sbjct: 1492 VTQRAELEVKERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVR--GRPKPTVTWWKNGKEL 1549 Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ 366 + EI + + TL Y L +E E SY Sbjct: 1550 RDGKHVEIRSGGTYHTL------------YILRSE--------------EEDAGSYKCLA 1583 Query: 367 RSQYITDTQQRETEERIE-ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425 R+ + +R E ++E + K AP+ + +TE C V G P P W Sbjct: 1584 RND--VGSAERLFEVQVEGVKPKEEAPKLTSQLRSARITESDDFELACDVKGTPDPSYEW 1641 Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485 +D+ ++ D H + L V LSD G T +N G T L++++ Sbjct: 1642 LKDDKPVKFD-RHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKS 1700 Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD--G 543 + P+ +E E + + P + W I + D Sbjct: 1701 KS--KPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEED 1758 Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 G ++ I + D Y+ A N G T+ RA L Sbjct: 1759 GTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAEL 1793 Score = 87.4 bits (207), Expect = 2e-16 Identities = 114/462 (24%), Positives = 185/462 (40%), Gaps = 38/462 (8%) Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135 G + +EWF +G+ + ++ + L++L T DSGTY ATN G A Sbjct: 3906 GKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRI 3965 Query: 3136 VKLECV---DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192 L K K P F T + + + +G F V V P I+WY + P+ Sbjct: 3966 FNLNVTAIAPKEKWSSPIFVTELSPLS-VTEGDYTKFVAHVSGVPLPS--IQWYKDDNPI 4022 Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESL 3252 + RI+T D V L I D G+Y N+ G + A ++ + G Sbjct: 4023 SSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYG------ 4076 Query: 3253 QPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQ------SAHFEARL 3306 +P R++E G++ + S P + + TKL + + + R Sbjct: 4077 KPAITQLYRDVEGFDGSESELTVQVSGVPAAEVEWFRGKTKLFPSERSYKIIATNEYGRT 4136 Query: 3307 VPVDDPDLK-----VEWFYNGKKLPHGHRYRTFHDFGIVIL----DILYCYEENSGEYEC 3357 + D +K E+ K R R F + ++L ++ +++ YE Sbjct: 4137 GALIDLTVKERLFGPEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYET 4196 Query: 3358 VATNKLGRDSTK-ANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVR-RKDTSVEEE 3415 + RDS + N+ + ++ R G + TL+ VR R+ V+ Sbjct: 4197 SRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKAVRPRRGNEVQAC 4256 Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT--FC 3473 K + T ++N+ + EG + R+T P VEW+ + + G R++T Sbjct: 4257 KPQ----TSKMANVTAV-EGWKVQLDTRMTGYPVP--IVEWFRGEEKITDGGRYKTARME 4309 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 D G L IS EDSG Y A NN GEA T A + V+GK Sbjct: 4310 DEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTVKGK 4351 Score = 87.0 bits (206), Expect = 3e-16 Identities = 50/192 (26%), Positives = 87/192 (45%), Gaps = 4/192 (2%) Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683 E+ EP+ +V E AI F ++ GKP+PT+ WYK ++++ + F++ D YT Sbjct: 2338 ELKEPV---VVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATY 2394 Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKT 4742 A ED G Y C A N G+ + L V P + P+ + L+ +++ EG Sbjct: 2395 SASAEDAGTYTCEASNKLGKCSRDFNLHVDVPKEQWEAPSFKSQLQPVILEEGGTGVLVG 2454 Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802 ++ K PTIQW+++ + + +G ++ D G + C G+ Sbjct: 2455 EVAGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCGEA 2514 Query: 4803 ETSAKLVVKSKT 4814 + A + V T Sbjct: 2515 SSKALVGVNRGT 2526 Score = 86.2 bits (204), Expect = 6e-16 Identities = 124/481 (25%), Positives = 189/481 (39%), Gaps = 45/481 (9%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 G+ P T+ K + EG+ Y+ + TG VI W+ +G+ I+A R++ + Sbjct: 182 GKAPTVTSELKPD-KVQEGE--QYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDGT 238 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 L I K D GTY TN G + LE K KP ++N+E + +G Sbjct: 239 TSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKP--AKPEVVRKMENVESV-EG 295 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV--LDIAYTQNHDSGEY 3222 A FE P K EW+H+ + + S+R K +D L I+ + DSG Y Sbjct: 296 SDAFFEVKFKGYPIP--KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAY 353 Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282 C A N+ GE RA + K + L I E++ Q + T + +P Sbjct: 354 QCIASNEAGECNLRADLKV--KNKPFAPEFADGDLEPI-EVKEDQAVNVRLTVTGNPKPE 410 Query: 3283 ----KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338 K TQ+ D KL + +P + + ++F P G RTF Sbjct: 411 VTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASN-PLGSPKRTF-KVT 468 Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398 +V + E SG + G K ++ N LD + G K++ Sbjct: 469 VVPKGVAPVIE--SGLMPLQVRKETG---AKWSV------NTTLD-------DAGEYKVK 510 Query: 3399 TLED--SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456 + S+ D +V++ K K P F + ++ L E E FE + P VEW Sbjct: 511 VTNEVGSVTSLADINVQKAKVK-PEFLRKVEDVTAL-ETEQVWFEIPI--QGYPRPIVEW 566 Query: 3457 YWNGKSLKAGSRF--RTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514 Y +K G RF + L I EDSG Y C A N+ G+ ++ V Sbjct: 567 YRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNE 626 Query: 3515 K 3515 K Sbjct: 627 K 627 Score = 83.4 bits (197), Expect = 4e-15 Identities = 131/617 (21%), Positives = 242/617 (39%), Gaps = 51/617 (8%) Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128 E S G S + W+ + + + + + D+G+Y C A N+ Sbjct: 1822 EVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNR 1881 Query: 3129 WGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187 G A + +E V K++ + P FTT ++ I+ + +G++ F C V +P + WY Sbjct: 1882 VGSATRNFNVEIEVPKARDEAPSFTTTLKPID-VTEGENHTFICRVHARPEPS--VTWYR 1938 Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGV 3247 N + R +T D L + + D+G+Y C A N G+ F C + V Sbjct: 1939 NKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAF------CTAEMTV 1992 Query: 3248 YLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF--EAR 3305 ++P + E +G S P + ++++G E Sbjct: 1993 NKREVKPVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGD 2052 Query: 3306 LVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVA------ 3359 + D+ + + K + + RT + +VI + Y E + + +A Sbjct: 2053 YHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQN 2112 Query: 3360 --TNKLGRDSTKANLKCTSKENLIL-DSQLPRGMEGGLEKLQ----TLED---------- 3402 TN R +++ + L++ D ++ GGL L+ TL+D Sbjct: 2113 AITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATN 2172 Query: 3403 ---SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWN 3459 S RR VE K +APVF L + + EG+N + ++ P VEWY + Sbjct: 2173 SIGSTSRRIIVDVEALK-EAPVFVSKLRPLF-VTEGDNVSWMCKVAGMPRPT--VEWYRD 2228 Query: 3460 GKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN-- 3517 + L+A +R++ D L +S +D G Y C N+ G A ++A ++V K N Sbjct: 2229 NQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKP 2288 Query: 3518 IILES----QLPKGMEGTID-KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSEN 3572 ++E Q +G E D + + L T + + + +++ E+ Sbjct: 2289 KVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQES 2348 Query: 3573 SSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTC 3632 + +F+ R+ + W+ +G+ + R + + DAG YTC Sbjct: 2349 DAINFKVRV--RGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTC 2406 Query: 3633 KATNRHGEATVSCKLQV 3649 +A+N+ G+ + L V Sbjct: 2407 EASNKLGKCSRDFNLHV 2423 Score = 82.6 bits (195), Expect = 7e-15 Identities = 54/192 (28%), Positives = 82/192 (42%), Gaps = 4/192 (2%) Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 + ++E P+ + + + EG RFD VTG P P V W+ +I D + + Sbjct: 5631 LNVNEGYSKPEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSSTL 5690 Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS--TL 500 G +L I + D G+ CVA N+ GET L+V EK P+F E + Sbjct: 5691 TSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEKH--YGPEFAEEELDWSK 5748 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 R+GE + G P P + W KDG+ + + + + G L I D Sbjct: 5749 TARKGENARITFTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGT 5808 Query: 561 YQCTAQNVAGST 572 Y C AQ+ G + Sbjct: 5809 YVCEAQSRLGKS 5820 Score = 81.8 bits (193), Expect = 1e-14 Identities = 65/264 (24%), Positives = 110/264 (41%), Gaps = 20/264 (7%) Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481 V E + A + P P ++WY+ + + + + T L IR+ ++D+ + Sbjct: 2107 VREGQNAITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTY 2166 Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541 A N G+ S ++V+ + + P F + + VT G V KV G Sbjct: 2167 ICKATNSIGST--SRRIIVDVEALKEA-----PVFVSKLRPLFVTEGDNVSWMCKVAGMP 2219 Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601 V W ++ + ++ D R K+ + +L + EA +D G Y CV NSAG A AE Sbjct: 2220 RPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAEL 2279 Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661 V A K P++IE + D EG F + G P P V WY+ Sbjct: 2280 QVDKKANK-------------PKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSI 2326 Query: 4662 LIKPSKYFQMSRTADEYTLRISEA 4685 ++ K++ + ++ S+A Sbjct: 2327 KVRNEKFYGDDELKEPVVVQESDA 2350 Score = 81.4 bits (192), Expect = 2e-14 Identities = 84/341 (24%), Positives = 145/341 (42%), Gaps = 30/341 (8%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 PEF + + + EGQ A ++ S +EW+ + + +I G+ Sbjct: 2095 PEFEDFDEKRIAVREGQNAITNMTI--RARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYY 2152 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 LEI D+GTY C+ATN G + ++ V+ K + P F + ++ + + +G + Sbjct: 2153 LEIRKATLDDAGTYICKATNSIGSTSRRIIVD-VEALK-EAPVFVSKLRPL-FVTEGDNV 2209 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 + C V + P +EWY + QP+R TR K D L ++ D G Y C Sbjct: 2210 SWMCKVAGMPRP--TVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVIT 2267 Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287 N G F+ A + K +P + K+ ++++++G + + S P +T Sbjct: 2268 NSAGSAFSSAELQVDKKAN------KPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTW 2321 Query: 3288 IQDVTKLVEGQSAHFEARL---VPVDDPD-LKVEWFYNGKKLP------HGHRYRTFHDF 3337 ++ K V + + + L V V + D + + GK +P G R F Sbjct: 2322 YRNSIK-VRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRF 2380 Query: 3338 GIVILDILYCY------EENSGEYECVATNKLGRDSTKANL 3372 I +Y + E++G Y C A+NKLG+ S NL Sbjct: 2381 EIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNL 2421 Score = 81.4 bits (192), Expect = 2e-14 Identities = 59/179 (32%), Positives = 76/179 (42%), Gaps = 4/179 (2%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V EG V G+P P V WF D Q+ + N+ L L + T +DSG Sbjct: 3892 VREGCEVSMMANVRGKPAPTVEWF-KDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGT 3950 Query: 463 VTCVARNKSGETAFQCRLNVIE---KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519 VA N G LNV KE+ +P FV S L+V EG+ A G P Sbjct: 3951 YKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTELSPLSVTEGDYTKFVAHVSGVPL 4010 Query: 520 PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 P I W KD PI N +R DG L I + D Y+ +N +GS + A+L Sbjct: 4011 PSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKL 4069 Score = 81.0 bits (191), Expect = 2e-14 Identities = 112/456 (24%), Positives = 189/456 (41%), Gaps = 51/456 (11%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVYAFGM 3105 PE +++ + EG A +E G EWF++ K IE S R I T Sbjct: 281 PEVVRKMENVESV-EGSDAFFEVKF--KGYPIPKREWFHDSKKIEPSSRFKITTDDTEQT 337 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTT-HIQNIEGLKDG 3164 L I + DSG Y C A+N+ G+ + L+ K+K P F ++ IE +K+ Sbjct: 338 SSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV--KNKPFAPEFADGDLEPIE-VKED 394 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 Q+ + TV +P ++ WY +G + + ++K + L I +D G+Y C Sbjct: 395 QAVNVRLTVT--GNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFC 452 Query: 3225 RAYNKYGEDFTRATINCYGKG-------GVYLESLQPDSLAKIRELESLQGAQQ------ 3271 A N G + KG G+ ++ ++ AK +L A + Sbjct: 453 EASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVT 512 Query: 3272 -QTPSTPSAEP---------PKFITQIQDVTKLVEGQSAHFEARLVPVDD-PDLKVEWFY 3320 + S S P+F+ +++DVT L E + FE +P+ P VEW+ Sbjct: 513 NEVGSVTSLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFE---IPIQGYPRPIVEWYR 568 Query: 3321 NGKKLPHGHRYRTFH--DFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK- 3377 ++ G R+ + + L I E+SG Y+CVA+N G+ + NL K Sbjct: 569 GTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNEKV 628 Query: 3378 ENLILDSQL-PRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGE 3436 D ++ P ++ G E +LE + + V K P+ ++++ + E Sbjct: 629 VQPEFDKEVKPIEVKHGEEATTSLE--IKGKPKPKVTWYKDLVPLLETRSIQLKSVGD-E 685 Query: 3437 NAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF 3472 + TP D+ K E + KAG+ FR+F Sbjct: 686 HTLEIINATPDDEGKYKCE-----ATNKAGTAFRSF 716 Score = 80.6 bits (190), Expect = 3e-14 Identities = 68/295 (23%), Positives = 115/295 (38%), Gaps = 18/295 (6%) Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 V V + +V G + W K+G+ V+ R +I YT A +D+G Sbjct: 2343 VVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAG 2402 Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642 Y C A N G+ D V D PK Q +A P L+ I+ EG Sbjct: 2403 TYTCEASNKLGKCSRDFNLHV------DVPKEQWEA----PSFKSQLQPVILEEGGTGVL 2452 Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 ++ GKPLPT+QW K D + + + EA D G Y+C+ N G Sbjct: 2453 VGEVAGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCG 2512 Query: 4703 RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 + A + V + + + +V+ EG ++F +I P ++W + Sbjct: 2513 EASSKALVGVNRGTVGPEI--IEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLT 2570 Query: 4763 ETPDFQMIHEGNNAV----LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + +++ E N + L++ + TG + A+ G+ + L V + Sbjct: 2571 DGVKYRI--ESNPEIGLYSLVVSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER 2623 Score = 79.8 bits (188), Expect = 5e-14 Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 8/195 (4%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 G P TT DI I +G+ + TG+ + +EWF +GK ++A+HR+ + Sbjct: 727 GETPTITTEMTDIQAI-DGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEER 783 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 M+ L K D G Y C +N +G + +++ D+S KP T +++ + +++ Sbjct: 784 MIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS--LKPEVITSMRDCDCVEE- 840 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 ++A F C P+ +IEW+ P+ R + L I+ + D+G Y C Sbjct: 841 ETASFHCEF--SGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKC 898 Query: 3225 RAYNKYGEDFTRATI 3239 A N G+ TRA + Sbjct: 899 VASNAAGKTTTRAEL 913 Score = 79.8 bits (188), Expect = 5e-14 Identities = 87/339 (25%), Positives = 141/339 (41%), Gaps = 49/339 (14%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066 P+ VEWY + + G L+I A +D GTY+CKATN++G T+ Sbjct: 2123 PSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGS--TSRR 2180 Query: 2067 VKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDR 2126 + VD ++ LK E P + + RP+F+T EGD Sbjct: 2181 IIVDVEA-----------LK--------EAPVFVSK----LRPLFVT---------EGDN 2208 Query: 2127 AHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186 + C+V + P T++W+ + Q +RA R++ D +L + +D G Y C Sbjct: 2209 VSWMCKVAGM--PRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVI 2266 Query: 2187 TNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ-----GHSTRIEV----EEP 2237 TN G A ++ L+V N + N ++ + EA+ R EV Sbjct: 2267 TNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSI 2326 Query: 2238 KISPPRFV--TELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295 K+ +F EL+ V E +F+ +V P I +Y +G+ ++ RF I Sbjct: 2327 KVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPT--IVWYKDGEMVRDVRRFEIRS 2384 Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 + EDAG Y+ +A N LG C+ ++ V Sbjct: 2385 RGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHV 2423 Score = 78.6 bits (185), Expect = 1e-13 Identities = 67/252 (26%), Positives = 110/252 (43%), Gaps = 16/252 (6%) Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021 S +R + D + E P F ++ VTEG V + + PT VEWY + +P++ Sbjct: 2176 STSRRIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLR 2233 Query: 2022 QGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG--LYLDT 2079 R+K +D +L + A +D G Y C TN+ G A +++ ++VD K+ ++ Sbjct: 2234 ADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEK 2293 Query: 2080 LDEQRLKKIQELEKYER----PKPIEEEQPGQRPVFLTALTSLENLK------EGDRAHF 2129 +++ + + E R P+P V + LK E D +F Sbjct: 2294 MNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINF 2353 Query: 2130 ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNK 2189 + RV P TI W+ +G+ +R R+ AED+GTY C+A+NK Sbjct: 2354 KVRVR--GKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNK 2411 Query: 2190 LGEAVNTCTLKV 2201 LG+ L V Sbjct: 2412 LGKCSRDFNLHV 2423 Score = 78.2 bits (184), Expect = 2e-13 Identities = 62/258 (24%), Positives = 109/258 (42%), Gaps = 16/258 (6%) Query: 1689 NQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748 N + TS+ R E + +APVF ++ + V E + ++ G P+ VEW R Sbjct: 2172 NSIGSTSR--RIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMCKV--AGMPRPTVEWYR 2227 Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 + P+ A R D +L + + +D G Y C N G A +S+ L V KA+ Sbjct: 2228 DNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANK 2287 Query: 1809 QLESQHESALQKIQQLED--SSRYQRREDVEV--------AVNQAPRFITQLNGPTKLSE 1858 + + +Q ++ E R+ EV N+ +L P + E Sbjct: 2288 PKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQE 2347 Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918 + +++ R+ P P + WY +G++++ R+ + + ED+G YT Sbjct: 2348 SDAINFKVRVRGKPVPT--IVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYT 2405 Query: 1919 CKAINNLGQAVSSIRLNV 1936 C+A N LG+ L+V Sbjct: 2406 CEASNKLGKCSRDFNLHV 2423 Score = 77.8 bits (183), Expect = 2e-13 Identities = 57/229 (24%), Positives = 105/229 (45%), Gaps = 10/229 (4%) Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130 S TG + I W+ +G+ ++ + RI + L IL K D+GTY+C A N+ G Sbjct: 2856 SFTVTGSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIG 2915 Query: 3131 QAEISVKLE-CVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189 A S +++ K KG+ P F+ ++ I +++ S C V P +I+W NG Sbjct: 2916 AAYRSFEVDVTAPKVKGEAPSFSLELRPIAAIEEFDS-KLICHV--SGKPKPQIKWTKNG 2972 Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYL 3249 +P+ R++T D L I + D+G Y C A N G + A + V Sbjct: 2973 KPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALT------VSR 3026 Query: 3250 ESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQ 3298 +++P K+ ++++ +G + + + P + + + + EG+ Sbjct: 3027 RNMRPLITHKLHDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGR 3075 Score = 77.4 bits (182), Expect = 3e-13 Identities = 137/644 (21%), Positives = 238/644 (36%), Gaps = 82/644 (12%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P+ V WY+D R + + + ++ A DAGSY A N++G A + Sbjct: 1831 PSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVGSATRNFN 1890 Query: 860 IRV--------AARSTVTA---DLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQK 908 + + A T T D+ E +I + VP+ + Sbjct: 1891 VEIEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWYRNKNEIVPDGRSR 1950 Query: 909 PEFKTP----IKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVE-ASSRITTFFN 963 F I I IK+ G A PIG + E + R V+ ++ F Sbjct: 1951 TTFDGETYKLILQDIKIKDAGQYECIAS-NPIGKAFCTAEMTVNKREVKPVIKEVSKTFE 2009 Query: 964 FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES-QHPGGLEKIQY 1022 V V T Y+ + + + D S + G Y Sbjct: 2010 VSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAASY 2069 Query: 1023 LEDASRYSKRT--EEEVKITQK---PRFLGPLKGTNKIVEGQSA--HFEARVEPQSDLTM 1075 A + RT ++ IT++ P F + + EGQ+A + R P D Sbjct: 2070 KCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTIRARPSPD--- 2126 Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 VEWY + S +I G L+I +D+G Y A N+ G + Sbjct: 2127 -VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIG--------ST 2177 Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195 R +D ++ P++ +SK +P+F V+EG N+ Sbjct: 2178 SRRIIVDVEALKEA---------------PVF----VSKLRPLF---------VTEGDNV 2209 Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255 C++ M PT VEW+ + + + +R+K +D +L + A D G Y Sbjct: 2210 SWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVIT 2267 Query: 1256 NHLGSAHTSAIVRVIERSD---IVTDTQNEQAIEQIQLLEDAARRTKQVREDIT------ 1306 N GSA +SA ++V ++++ ++ + Q +E + D R + R ++T Sbjct: 2268 NSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFD-VRFSGLPRPEVTWYRNSI 2326 Query: 1307 VMQAPQF---SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363 ++ +F + E ++ + R++ G + W+ +G+ ++ RF Sbjct: 2327 KVRNEKFYGDDELKEPVVVQESDAINFKVRVR--GKPVPTIVWYKDGEMVRDVRRFEIRS 2384 Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407 D S ED+G YTC+A+N+LG+ L V K+ Sbjct: 2385 RGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHVDVPKE 2428 Score = 77.0 bits (181), Expect = 4e-13 Identities = 56/187 (29%), Positives = 86/187 (45%), Gaps = 11/187 (5%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P FT + I DI EG + + TG V+EW+ + + + HR+RT Y+ G VV Sbjct: 5544 PAFTAPLQHI-DILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRT-YSDGRVV 5599 Query: 3108 LEILG-TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166 + +L T +D+G + C N G S L V++ KP ++ IE + G+ Sbjct: 5600 ILLLRQTNISDAGVFKCVLRNDLGTVASSASLN-VNEGY-SKPEINEKLKKIEAFEGGE- 5656 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI-KTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 A F+ V P +++WY + R T++ G L I + D G Y C Sbjct: 5657 ARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYGCV 5714 Query: 3226 AYNKYGE 3232 A N+YGE Sbjct: 5715 AVNEYGE 5721 Score = 76.2 bits (179), Expect = 6e-13 Identities = 80/349 (22%), Positives = 140/349 (40%), Gaps = 15/349 (4%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 P +EWY + + L +R+K+ D +L L + +D G+Y C N G AF+S+ Sbjct: 2219 PRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAE 2278 Query: 3001 VYCTSKDN---LIERTQHPKGTEGLEKIQNLEDS--LRKEPGQQPDDDTGRPPEF--TTV 3053 + K N +IE+ + EG E ++ S R E + R +F Sbjct: 2279 LQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDE 2338 Query: 3054 FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGT 3113 K+ V + E +++ + G I W+ +G+ + R + Sbjct: 2339 LKEPVVVQESDAINFKVRV--RGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSA 2396 Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172 D+GTY+C A+NK G+ L V K + + P F + +Q + L++G + Sbjct: 2397 SAEDAGTYTCEASNKLGKCSRDFNLHVDVPKEQWEAPSFKSQLQPVI-LEEGGTGVLVGE 2455 Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 V P I+W + P+ R++ D + D G Y C N+ GE Sbjct: 2456 V--AGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCGE 2513 Query: 3233 DFTRATINCYGKGGVYLESLQ-PDSLAKIRELESLQGAQQQTPSTPSAE 3280 ++A + +G V E ++ P L + +S + + TP E Sbjct: 2514 ASSKALVG-VNRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVE 2561 Score = 75.8 bits (178), Expect = 8e-13 Identities = 58/252 (23%), Positives = 109/252 (43%), Gaps = 15/252 (5%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 PEF +KD +D +GQ + + G I W +G+ + + ++ + Sbjct: 922 PEFED-WKDTIDALDGQDVNISTWV--RGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHG 978 Query: 3108 LEILGTKTTDSGTYSCRATNKWG--QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165 L + D+G Y+CRA N G ++++ +E + K KG P F + ++ IE + +G Sbjct: 979 LVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEALQK-KGDTPTFMSKLEPIE-ITEGD 1036 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 C V P+ ++W+ + ++ S R K D L + + D G Y C Sbjct: 1037 DFQLSCNVTGRPQPE--VQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDDDGVYKCV 1094 Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFI 3285 N +G ++A + V + L+P+ L K+ ++ +++G + A P I Sbjct: 1095 VTNNFGSVSSKADVT------VLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPEI 1148 Query: 3286 TQIQDVTKLVEG 3297 TK+ +G Sbjct: 1149 EWYLGATKITDG 1160 Score = 75.4 bits (177), Expect = 1e-12 Identities = 63/247 (25%), Positives = 111/247 (44%), Gaps = 17/247 (6%) Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894 DVE A+ +AP F+++L P ++EG + + C++ P P VEWY + + L++ R++ Sbjct: 2184 DVE-ALKEAPVFVSKLR-PLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWK 2239 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954 D +L + +D G Y C N+ G A SS L V K + + + + ++ Sbjct: 2240 MDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQT 2299 Query: 1955 IQYLED--DSRYKRAVQDD------SFVVEKPQF--GKPIKN-AEVTEGHPVHLEATLTP 2003 ++ E D R+ + + S V +F +K V E ++ + + Sbjct: 2300 VEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVR- 2358 Query: 2004 VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063 P + WY +G V+ RF+ A AED GTY C+A+N +G+ Sbjct: 2359 -GKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSR 2417 Query: 2064 TSSVKVD 2070 ++ VD Sbjct: 2418 DFNLHVD 2424 Score = 74.9 bits (176), Expect = 1e-12 Identities = 122/526 (23%), Positives = 202/526 (38%), Gaps = 46/526 (8%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 EI + + P FT +K IDV EG F CRV +P+ + W+ N R Sbjct: 1892 EIEVPKARDEAPSFTTTLKP-IDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGR 1948 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803 T D L + I +DAG+Y C A+N G K C+A+ + P Sbjct: 1949 SRTTFDGETYKLILQDIKIKDAGQYECIASNPIG------KAFCTAEMTVNKREVKPVIK 2002 Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP---- 3859 K E+ G + E VS P + + +G RF+ E Sbjct: 2003 EVSKTFEVSEGGTASI---EVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIR 2059 Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 + + + K + + RT Y V + Y + + AV + T TI Sbjct: 2060 DVGDQAAASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTI 2119 Query: 3920 SCKKLPDI-------ILQNQVPRGMKRSEALTQME---ATIK-------KYTSEVYLTED 3962 + PD+ +L + +K L +E AT+ K T+ + T Sbjct: 2120 RARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSR 2179 Query: 3963 DLY-DVDK-KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKN 4020 + DV+ K+ P FV++++ + E + + C++A G P VEW+ + +PL Sbjct: 2180 RIIVDVEALKEAPVFVSKLRP-LFVTEGDNVSWMCKVA--GMPRPTVEWYRDNQPLRADT 2236 Query: 4021 RFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGIVYDSQL 4077 R+ +D ++ +D G Y C TN G + A V K KP ++ Sbjct: 2237 RWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMND 2296 Query: 4078 PKHMKSIEKIREMEASWQVTPEQVVEES--KARCPPVFVS--LPDAVTVEEGEWARFCCR 4133 + ++ E ++ S PE + K R + L + V V+E + F R Sbjct: 2297 VQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVR 2356 Query: 4134 VTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTG 4178 V G P P ++W +G + + R+++ G +Y F D G Sbjct: 2357 VRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAG 2402 Score = 74.5 bits (175), Expect = 2e-12 Identities = 83/395 (21%), Positives = 142/395 (35%), Gaps = 38/395 (9%) Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477 +P V E + G+P P ++W+++ + N+ + + L + + D Sbjct: 3888 EPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQAD 3947 Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537 S + VA N G+A NL V + + P F ++VT G + V Sbjct: 3948 SGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWS--SPIFVTELSPLSVTEGDYTKFVAHV 4005 Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 +G + W K+ + + R + + LLI + +D G+Y+ V N +G A Sbjct: 4006 SGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATS 4065 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 A+ V + P I + +D +G E + ++ G P V+W+ Sbjct: 4066 SAKLSV-------------REEYGKPAITQLYRDVEGFDGSESELTVQVSGVPAAEVEWF 4112 Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717 +G + PS E YK +A N GR L V + Sbjct: 4113 RGKTKLFPS-----------------------ERSYKIIATNEYGRTGALIDLTVKERLF 4149 Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777 +V E A + +P + W ++G + ET M + Sbjct: 4150 GPEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQY 4209 Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812 L I +D GT+ C A + G S L VK+ Sbjct: 4210 LNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKA 4244 Score = 73.7 bits (173), Expect = 3e-12 Identities = 60/233 (25%), Positives = 102/233 (43%), Gaps = 16/233 (6%) Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128 E S + G ++W+ GK + S + + + I K SG Y C ATN Sbjct: 5461 ELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEATNS 5520 Query: 3129 WGQAEISVKLEC---VDKSKGQKPRFTTHIQNIEGLKDGQSAHF--ECTVVPVDDPDMKI 3183 G A L V + P FT +Q+I+ L +G + F E T VPV + Sbjct: 5521 NGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDIL-EGDTTRFIGEITGVPVP----VV 5575 Query: 3184 EWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243 EWY + +P+ R++T SD V+L + T D+G + C N G + A++N Sbjct: 5576 EWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLN--- 5632 Query: 3244 KGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296 V +P+ K++++E+ +G + + + PP + + TK+ + Sbjct: 5633 ---VNEGYSKPEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITD 5682 Score = 72.1 bits (169), Expect = 1e-11 Identities = 60/242 (24%), Positives = 107/242 (44%), Gaps = 15/242 (6%) Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121 +GQ+ +A ++P + ++ W+ +G +E S R+ + + DSG Y Sbjct: 4370 KGQMVSVKA-IVPAHPKQVI--WYKDGIRLEDSRRVNLRSVGERYYVVVPSASFEDSGIY 4426 Query: 3122 SCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179 C T++ + +E V KS P F + +++++ +D +SA F C V P Sbjct: 4427 KCETTSEKETTSQLFDIHIEDVCKS-ALAPGFKSALRSLDVTED-ESAEFRCEVS--GSP 4482 Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239 +I+W+ N QP+ +RI T SD L I D+G Y C A N G + A + Sbjct: 4483 APRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADL 4542 Query: 3240 NCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQS 3299 N V ++P + ++RE+ ++ G + P I +D+T+L+ Sbjct: 4543 N------VSHCRMKPTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGR 4596 Query: 3300 AH 3301 H Sbjct: 4597 FH 4598 Score = 71.3 bits (167), Expect = 2e-11 Identities = 59/277 (21%), Positives = 110/277 (39%), Gaps = 12/277 (4%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 + G A+F+ + G P P V W + K + K+ + + G SL+IK + D G Y Sbjct: 4 ESGEARFDVTIEGYPKPTVEWYQGKNKIGSSGKHKI-LEDDDGKCSLIIKDLTKDDAGAY 62 Query: 145 TCTARNQYGEAI----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQ 200 C A N G+ SV + + S ++ G Sbjct: 63 KCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVW 122 Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES--DVQISTEIDR 258 + + + T D STDD + + + K +G S D ++ ++ Sbjct: 123 YKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKG 182 Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318 P + + + K+QEG +F ++G P+P ++W+K+GQ + + + Sbjct: 183 -----KAPTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDG 237 Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 +TL +++ ++ D G Y + N G I ++ L V Sbjct: 238 TTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEV 274 Score = 71.3 bits (167), Expect = 2e-11 Identities = 55/202 (27%), Positives = 92/202 (45%), Gaps = 12/202 (5%) Query: 4623 PEIIEP--LKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYT 4679 PE IE KIV E + ++G P P V W+K G +L + S+ SR + +Y Sbjct: 4151 PEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQY- 4209 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRV--TVAAKLKVTQPDQADNLPALTP----LRDIVVY 4733 L I P+D G Y C A + G + +K +P + + + A P + ++ Sbjct: 4210 LNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKAVRPRRGNEVQACKPQTSKMANVTAV 4269 Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTF 4791 EG Q T++T P ++W R I + ++ + + L+I + ED+G++ Sbjct: 4270 EGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSY 4329 Query: 4792 TCRATTAAGQVETSAKLVVKSK 4813 A+ G+ T A+L VK K Sbjct: 4330 RAVASNNLGEATTLAELTVKGK 4351 Score = 70.9 bits (166), Expect = 2e-11 Identities = 53/222 (23%), Positives = 96/222 (43%), Gaps = 13/222 (5%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P+ ++ +++ EG+ + + ++ TG + W+ +GK + + I Sbjct: 88 PQIKEKEQEPIEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF 145 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I DSG Y C A NK G + + K KG+ P T+ ++ + +++G+ Sbjct: 146 LSIPKATPNDSGKYKCEAKNKIGTSARDFDVNV--KVKGKAPTVTSELKP-DKVQEGEQY 202 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 F C V P I WY +GQP++ R+K D L I + D G Y Sbjct: 203 KFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEIT 260 Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269 N G + A + V + +P+ + K+ +ES++G+ Sbjct: 261 NDLGSISSTADLE------VTPKPAKPEVVRKMENVESVEGS 296 Score = 70.5 bits (165), Expect = 3e-11 Identities = 65/282 (23%), Positives = 121/282 (42%), Gaps = 12/282 (4%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 +P I E+ + +G + + + G P P V W + PL + ++ + + + Sbjct: 87 APQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYFL 146 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAI--CSVYIQPEGXXXXXXXXXXXXXYRHVSETVE 187 S I + P D G+Y C A+N+ G + V ++ +G V E + Sbjct: 147 S--IPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPD---KVQEGEQ 201 Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247 +K + K D D F T L+++V + T + Sbjct: 202 YKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFD-GTTSTLLIKDVKQDDKGTYKVEIT 260 Query: 248 SDV-QISTEIDRSLGP-VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 +D+ IS+ D + P + P++ +K N + EG+DA F+V+ G P P+ WF + ++ Sbjct: 261 NDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKK 320 Query: 306 LINSNKHEIIT--THNHTTLRVRNTQKSDSGHYTLLAENPNG 345 + S++ +I T T ++L + + + DSG Y +A N G Sbjct: 321 IEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAG 362 Score = 70.5 bits (165), Expect = 3e-11 Identities = 57/248 (22%), Positives = 97/248 (39%), Gaps = 10/248 (4%) Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823 E + P F+ L+ L + EG N + ++ + PT VEWY+D +P+ A +R F Sbjct: 2186 EALKEAPVFVSKLRPLF-VTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDF 2242 Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883 + SL + +D G Y N G A S+A ++V ++ + + +E Sbjct: 2243 DGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEG 2302 Query: 884 TXXXXXXXXX-----XXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGD 938 T + +K +K+ + ++E +F+ R+ G Sbjct: 2303 TEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVR--GK 2360 Query: 939 STLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSAN 998 + W KDG V R S + DAG YTC A N +G+ + N Sbjct: 2361 PVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFN 2420 Query: 999 LTIVTKKD 1006 L + K+ Sbjct: 2421 LHVDVPKE 2428 Score = 70.5 bits (165), Expect = 3e-11 Identities = 66/286 (23%), Positives = 110/286 (38%), Gaps = 16/286 (5%) Query: 80 NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPG 139 N +G + + ++ G P P+V W R + + + +Y E G SL+I + Sbjct: 4265 NVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLE 4324 Query: 140 DEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTE 199 D G Y A N GEA + +G S K Sbjct: 4325 DSGSYRAVASNNLGEATTLAELTVKGKHFARELEEGGCH----SRLTFRKGQMVSVKAIV 4380 Query: 200 QSRQTQKVAYTNG---TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEI 256 + Q + Y +G D + V Y ++ SF +S + S+ + ++++ Sbjct: 4381 PAHPKQVIWYKDGIRLEDSRRVNLRSVGERYYVVVPSASFEDSGIYKCETTSEKETTSQL 4440 Query: 257 -DRSLGPVS----PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311 D + V P R+ + E A+F+ ++SG+P PR+ WF N Q + S Sbjct: 4441 FDIHIEDVCKSALAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFMNDQPV--SRD 4498 Query: 312 HEIITTHNHTT--LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 IIT+ + L + D+G Y LA N NG ++ L V Sbjct: 4499 SRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 70.1 bits (164), Expect = 4e-11 Identities = 64/225 (28%), Positives = 93/225 (41%), Gaps = 10/225 (4%) Query: 3009 LIERTQHPKGTEGLEKIQNLEDSLRKEPGQ-QPDDDTGRPPEFTTVFKDIVDISEGQIAH 3067 L +++H GT E L ++ K Q Q + + P F + EG + Sbjct: 5210 LFTKSEHA-GTYSCEATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLLP-QNAREGDVVK 5267 Query: 3068 YEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATN 3127 + + TG IEW +G ++E+ R+ T Y L I DSG Y C N Sbjct: 5268 FSCKV--TGYPEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKN 5325 Query: 3128 KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187 G A S +L V K Q+PR + +++ + G+ A FE T+ P KI WY Sbjct: 5326 NSGWASSSAEL--VVGGKTQRPRLSDNMKELFATVGGE-ARFEVTMKATPKP--KICWYK 5380 Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 + +R R + G L I Q DSG Y A NK G+ Sbjct: 5381 DEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVASNKAGK 5425 Score = 69.7 bits (163), Expect = 5e-11 Identities = 49/155 (31%), Positives = 85/155 (54%), Gaps = 15/155 (9%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLI--PVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 +AP F++ ++ I E F+++LI G PK +++W +NG P+E+ RL T +D G Sbjct: 2933 EAPSFSLELRPIAAIEE----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYD-G 2987 Query: 1767 YVA-LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825 VA L++ V+ +D+GTY C A N G V+SS S+ +++ H K+ ++ Sbjct: 2988 IVAYLSIWQVSHDDAGTYECIASNAAG-TVSSSAALTVSRRNMRPLITH-----KLHDMK 3041 Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQ 1860 + R D+EV + +P + GP+ +SEG+ Sbjct: 3042 AYEGKEARFDIEVTGHPSPT-VEWFKGPSGISEGR 3075 Score = 69.7 bits (163), Expect = 5e-11 Identities = 145/628 (23%), Positives = 229/628 (36%), Gaps = 103/628 (16%) Query: 2777 ISH-LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSL 2833 I+H L+++ EG F+ V PT +EWF + G RY+ S + SL Sbjct: 3033 ITHKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEEQGKHSL 3090 Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893 ++ +D GIY C A Q+ GKA A+ Sbjct: 3091 IVSDLNADDDGIYKCVA-------------------------QNLAGKASTRAMLDV--- 3122 Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953 +A+ P + E PKP I+ E Q++ V + P +EW+ +GK Sbjct: 3123 -IARDFGPEFDEEESPKPV-IVNEGEEAQMM----------VSVRGRPKAVVEWFKDGKF 3170 Query: 2954 LEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK-DNLIER 3012 L R + S L + V D G Y C A + G + S T + K ++ Sbjct: 3171 LYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRS--SRTFDLSVKVPKPKDK 3228 Query: 3013 TQHPKGTEGLEKIQNLEDSLRK-------EPGQQPD---DDTGRPPE--FTTVFKDIV-- 3058 P + L ++ LE K EP + DDT E F T F V Sbjct: 3229 WSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCM 3288 Query: 3059 ------DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILG 3112 D E A EA + G +EWF + R R + L I Sbjct: 3289 LVFRKTDSFECSEARLEAHV--AGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISN 3346 Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172 D+G Y ATN+ G V L ++ G + + N + K G + T Sbjct: 3347 LHMEDTGPYKIIATNEHGSTGSVVDLTVKERLFGPEFLEEEGVWN-KVAKAGGFVNISFT 3405 Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 + +P + WY +G + +TR+ S ++I D+G YVC A ++ G Sbjct: 3406 LK--GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGT 3463 Query: 3233 DFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVT 3292 T+ ++ S+ G +++ S I Q + Sbjct: 3464 AIRSCTLEI--------------------KVPSMGGPEEKKIS------KALIGQGDNDV 3497 Query: 3293 KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH--DFGIVILDILYCYEE 3350 + VEG F+ R+ P VEW+ KL +Y+ + G+ L + ++ Sbjct: 3498 QAVEGWKVQFQTRITGYPYP--HVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKD 3555 Query: 3351 NSGEYECVATNKLGRDSTKANLKCTSKE 3378 + G Y+C+ATN G + + NL K+ Sbjct: 3556 DIGTYKCLATNSAGSSACRINLDVKDKQ 3583 Score = 68.9 bits (161), Expect = 9e-11 Identities = 51/209 (24%), Positives = 87/209 (41%), Gaps = 10/209 (4%) Query: 371 ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430 + D + + +S + P FV+ ++ G F RV G P P++ W+ + Sbjct: 4530 VNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDIT 4589 Query: 431 QIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489 ++ + + ++E G+ + L I NV DSG C+ N G+ CR ++ + + Sbjct: 4590 RLIN--RGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGKET--CRSQLVVEAEEF 4645 Query: 490 APKFVERFSTLNV----REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDGG 544 AP F E V R+ V L A G+P P + W KD + + + L + + Sbjct: 4646 APFFPEDEGQGAVPVVTRQDSEVELGAVVRGSPKPEVAWYKDDEDVATDADGLDVGSRDN 4705 Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 L R D Y+C A N G + Sbjct: 4706 VYFLRFARPSVKDGGLYKCVATNEHGEAS 4734 Score = 68.9 bits (161), Expect = 9e-11 Identities = 57/214 (26%), Positives = 93/214 (43%), Gaps = 13/214 (6%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISVKLE 3139 + W+ +G I S ++ + L IL TK+ +GTYSC AT+K G A+ V+++ Sbjct: 5181 VVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAKFDVQIQ 5240 Query: 3140 CVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199 + + + P F + + ++G F C V +P+ IEW +G M R+ Sbjct: 5241 APEAAP-KAPAFLKQLLP-QNAREGDVVKFSCKVTGYPEPE--IEWTRDGVSMESDERVT 5296 Query: 3200 TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAK 3259 T D L I + DSG Y C N G + A + GK + +P Sbjct: 5297 TWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK------TQRPRLSDN 5350 Query: 3260 IRELESLQGAQQQTPSTPSAEP-PKFITQIQDVT 3292 ++EL + G + + T A P PK ++T Sbjct: 5351 MKELFATVGGEARFEVTMKATPKPKICWYKDEIT 5384 Score = 68.5 bits (160), Expect = 1e-10 Identities = 63/230 (27%), Positives = 98/230 (42%), Gaps = 12/230 (5%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P F + L ++E + + C++ + + VEW+ + +PL +R K D L Sbjct: 2192 PVFVSKLRPLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSL 2249 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV--KGRQGIILEPQLPSHFKSGTESIQKL 3675 + +D G+Y C TN G A S +LQV K + ++E GTE+ + Sbjct: 2250 FLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDV 2309 Query: 3676 EETLHKREEIT--IEDEKPNPPRF--TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731 + R E+T K +F E+K+ + V E ++F RV G P I W Sbjct: 2310 RFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVR--GKPVPTIVW 2367 Query: 3732 FHNGRPFATGSRVHTLNDFGFIALDIDY-IYARDAGEYTCRATNKWGSAT 3780 + +G R + G I Y A DAG YTC A+NK G + Sbjct: 2368 YKDGE-MVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCS 2416 Score = 68.5 bits (160), Expect = 1e-10 Identities = 88/346 (25%), Positives = 133/346 (38%), Gaps = 38/346 (10%) Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTTDSG 3119 EG+ A ++ + TG S +EWF I R + + G L + D G Sbjct: 3044 EGKEARFDIEV--TGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDG 3101 Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL-KDGQSAHFECTVVPVDD 3178 Y C A N G+A L+ + + G P F + +G+ A +V Sbjct: 3102 IYKCVAQNLAGKASTRAMLDVIARDFG--PEFDEEESPKPVIVNEGEEAQMMVSVR--GR 3157 Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRAT 3238 P +EW+ +G+ + S R+ S L I + D G Y C A + G Sbjct: 3158 PKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRTFD 3217 Query: 3239 INCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKL---- 3294 ++ SL P +K+R LE+L+G + + S EP + +D T + Sbjct: 3218 LSVKVPKPKDKWSL-PAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHED 3276 Query: 3295 --------------------VEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334 E A EA + V P VEWF KL G RYR Sbjct: 3277 RFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRP--TVEWFLGSAKLCDGERYRLE 3334 Query: 3335 HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380 + L I + E++G Y+ +ATN+ G ST + + T KE L Sbjct: 3335 QTDNLYTLVISNLHMEDTGPYKIIATNEHG--STGSVVDLTVKERL 3378 Score = 67.7 bits (158), Expect = 2e-10 Identities = 118/510 (23%), Positives = 196/510 (38%), Gaps = 108/510 (21%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR--TSNDFGFAALDILTVYGEDSG 1915 EG + ++ RI +P P VEW++ + L G +YR ++ + G +L + V + +G Sbjct: 2542 EGNDSRFDVRIRGHPTPE--VEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTG 2599 Query: 1916 EYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVV 1975 Y A N G+A + + L V + L ++LEDD + + V+ FV Sbjct: 2600 HYRIVASNEHGKAQALLDLTVNER------------LYAPEFLEDDGEWSKVVRKGGFV- 2646 Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033 T T + +P V WY +G + R ++ D Sbjct: 2647 ----------------------NITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQ 2684 Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEK 2093 Y +I + EDTGTY+C+A N +G + + ++++ K +D+ D + Sbjct: 2685 Y--CNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEI--KEPKSVDSTDTR---------- 2730 Query: 2094 YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR 2153 PGQ + + E + G C V + I+WF +R Sbjct: 2731 ----------APGQL-IPVKHKFDFEGVPGGKA---RCDVLVKKSDIIDIEWFRGTNMLR 2776 Query: 2154 AGHRYR--TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211 G +Y+ + D ++L + ED+GTY C G+ + G +I Sbjct: 2777 DGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTT------IRGELHIKEKQ 2830 Query: 2212 QHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHD 2271 Q P L++ +V + K S P+ E+ + V T H Sbjct: 2831 QAPLFLDE-------------KVSQEKFSLPQ-GQEMNKSFTVTGSPTPH---------- 2866 Query: 2272 PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS 2331 I +Y +G+ L R I L I + PEDAG Y+ +A N +G + Sbjct: 2867 ----ITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFE 2922 Query: 2332 MTVTA---KGSIISESQRPEGLEKIRELES 2358 + VTA KG S S + I E +S Sbjct: 2923 VDVTAPKVKGEAPSFSLELRPIAAIEEFDS 2952 Score = 67.3 bits (157), Expect = 3e-10 Identities = 77/326 (23%), Positives = 138/326 (42%), Gaps = 40/326 (12%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P + K++ G+ A +E ++ T + W+ + T+ + R G+ Sbjct: 5345 PRLSDNMKELFATVGGE-ARFEVTMKATPKPKIC--WYKDEITLRSRDRYTMKEEDGIYT 5401 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I + +DSGTY A+NK G+ LE ++K+ P F + +E + + Sbjct: 5402 LIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKTVA--PEFPDR-ETLEQVVGVEGR 5458 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV-VLDIAYTQNHDSGEYVCRA 3226 E + V P ++WY G+ + H+++ TVS G + I ++ SG Y C A Sbjct: 5459 EVELSTVVKGLPRPSVKWYKEGK-LLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEA 5517 Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286 N G +N + + + P A ++ ++ L+G + +FI Sbjct: 5518 TNSNGTAHRDFVLNIQAQVPAE-QWVAPAFTAPLQHIDILEG-----------DTTRFIG 5565 Query: 3287 QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILY 3346 +I V VPV VEW+ + + + HR RT+ D +VIL + Sbjct: 5566 EITGVP--------------VPV------VEWYRDDRPVTRDHRLRTYSDGRVVILLLRQ 5605 Query: 3347 CYEENSGEYECVATNKLGRDSTKANL 3372 ++G ++CV N LG ++ A+L Sbjct: 5606 TNISDAGVFKCVLRNDLGTVASSASL 5631 Score = 66.9 bits (156), Expect = 4e-10 Identities = 54/200 (27%), Positives = 87/200 (43%), Gaps = 14/200 (7%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLI--PTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102 G P F+ + I I E +++ LI +G I+W NGK +E+ R+RT Y Sbjct: 2932 GEAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYD 2986 Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162 + L I D+GTY C A+N G S L + +P T + +++ Sbjct: 2987 GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTV--SRRNMRPLITHKLHDMKAY- 3043 Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS--DFGFVVLDIAYTQNHDSG 3220 +G+ A F+ V P +EW+ + R + +S + G L ++ D G Sbjct: 3044 EGKEARFDIEV--TGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDG 3101 Query: 3221 EYVCRAYNKYGEDFTRATIN 3240 Y C A N G+ TRA ++ Sbjct: 3102 IYKCVAQNLAGKASTRAMLD 3121 Score = 66.9 bits (156), Expect = 4e-10 Identities = 91/414 (21%), Positives = 166/414 (40%), Gaps = 51/414 (12%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G + ++G P P V W K+ L+ +K ++ + + I G Y Sbjct: 5456 EGREVELSTVVKGLPRPSVKWY-KEGKLLHTSK-ALTVSTSGDTHYVWIPSAKHEHSGRY 5513 Query: 145 TCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR 202 C A N G A + IQ + +H+ + +E T + E + Sbjct: 5514 RCEATNSNGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHI-DILEGD---TTRFIGEITG 5569 Query: 203 QTQKVAYTNGTDHSSTDDFKVDTFE-----YRLLREVSFRESITKRYVGESD---VQIST 254 V D T D ++ T+ LLR+ + ++ + V +D V S Sbjct: 5570 VPVPVVEWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSA 5629 Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE- 313 ++ + G S P+I +K + + EG +A+F + ++G P PRV W++ ++ + N++ Sbjct: 5630 SLNVNEG-YSKPEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSS 5688 Query: 314 IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373 +T+ +L +R ++ D G Y GC+ + Y T S V Sbjct: 5689 TLTSDGMASLTIRKIRQEDGGLY--------GCVAVNEY----GETTSIVD--------- 5727 Query: 374 TQQRETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQ 431 + + EK P+F + D T +G+ R V+G P P+V W+ D Sbjct: 5728 ---------LHVGEKHYGPEFAEEELDWSKTARKGENARITFTVSGNPRPDVVWY-KDGM 5777 Query: 432 IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485 + D H + + L I +T D+G C A+++ G++ L V E+ Sbjct: 5778 LLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKVEEQ 5831 Score = 65.7 bits (153), Expect = 9e-10 Identities = 65/247 (26%), Positives = 104/247 (42%), Gaps = 29/247 (11%) Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVN 1776 ++ I V E+QA + RL G+PK V W ++G + + +L L++ + Sbjct: 386 LEPIEVKEDQAVN--VRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKAS 443 Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSKA----------SLQLESQHESALQKIQQLED 1826 D G Y C A N LG + + V K LQ+ + + L+D Sbjct: 444 TNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDD 503 Query: 1827 SSRYQRREDVEVA---------VNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874 + Y+ + EV V +A P F+ ++ T L E + +E I+ YP P Sbjct: 504 AGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQGYPRP 562 Query: 1875 NMRVEWYFNGKVLQSGHRYRTSN--DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932 VEWY ++ G R+ S + +L I EDSG Y C A N+ G+ + + Sbjct: 563 I--VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALL 620 Query: 1933 RLNVQSK 1939 L+V K Sbjct: 621 NLDVNEK 627 Score = 65.3 bits (152), Expect = 1e-09 Identities = 50/180 (27%), Positives = 76/180 (42%), Gaps = 9/180 (5%) Query: 3082 IEWFYNGKTIEASHRIRTVYAF-GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140 +EW+ I +S + + + G L I D+G Y C ATN GQ + L Sbjct: 22 VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRGDLSV 81 Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 K K P+ Q + +G+S + + T+ P+ + WY +G+P+R + I Sbjct: 82 --KEKQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPE--VVWYKDGKPLRKTKSIDL 137 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG---EDFTRATINCYGKGGVYLESLQPDSL 3257 S L I +DSG+Y C A NK G DF + GK L+PD + Sbjct: 138 KSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFD-VNVKVKGKAPTVTSELKPDKV 196 Score = 65.3 bits (152), Expect = 1e-09 Identities = 121/542 (22%), Positives = 203/542 (37%), Gaps = 104/542 (19%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP F P ++ E Q+ + + P P V WY +G L + + Sbjct: 378 APEFADGDLEPIEVKEDQAVNVRLTVTGNPKPE--VTWYKDGTQLHDTKKLKLKATGDVH 435 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK------ESIIRDSQ---HESALE 1953 L I D G+Y C+A N LG + ++ V K ES + Q A Sbjct: 436 ELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKW 495 Query: 1954 KIQY-LEDDSRYKRAVQDDSFVVE------------KPQFGKPIKNAEVTEGHPVHLEAT 2000 + L+D YK V ++ V KP+F + +++ E V E Sbjct: 496 SVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIP 555 Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRF--KTTYDFGYVALDILYAYAEDTGTYMCKATNAV 2058 + P VEWY ++ G RF + + +L I A ED+G Y C A+N Sbjct: 556 IQGYPRPI--VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDA 613 Query: 2059 GEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSL 2118 G+ TT+ + +D +K+ + E + KPIE Sbjct: 614 GK--TTALLNLDVN-------------EKVVQPEFDKEVKPIE----------------- 641 Query: 2119 ENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAED 2178 +K G+ A ++ P +T W+ + + + L+I+ +D Sbjct: 642 --VKHGEEATTSLEIKGKPKPKVT--WYKDLVPLLETRSIQLKSVGDEHTLEIINATPDD 697 Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPK 2238 G Y C+ATNK G A + +KV + E QG + I E Sbjct: 698 EGKYKCEATNKAGTAFRSFDIKV-------------------KVAEPQGETPTITTE--- 735 Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298 +T+++ +G+ C V +PN +E++ +GK L++ R +F+ Sbjct: 736 ------MTDIQ----AIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEER 783 Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELES 2358 ++L + ED G Y N G +SA A+ + S +PE + +R+ + Sbjct: 784 MIALSFRPIKLEDMGRYKCVISNVFGSVSSA------AEVKVEDRSLKPEVITSMRDCDC 837 Query: 2359 AE 2360 E Sbjct: 838 VE 839 Score = 65.3 bits (152), Expect = 1e-09 Identities = 113/496 (22%), Positives = 189/496 (38%), Gaps = 90/496 (18%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 KPV ++ +S VSEG +E ++ G P VEW+H V G RF+ + + Sbjct: 1998 KPV-IKEVSKTFEVSEGGTASIEVKVS--GVPVPTVEWYHGSNRVLDGDRFQVTQEGDYH 2054 Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295 L I Y A N+ G R R+D+V T+ E A E ED Sbjct: 2055 TLSIRDVGDQAAASYKCVAFNNAG--------RTTYRADLVI-TEREYAPE----FEDFD 2101 Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355 + VRE + TN+ + R P VEW+ + + Sbjct: 2102 EKRIAVREGQNAI-----------------TNMTIRARPSP------DVEWYKGDTLLMS 2138 Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415 + L++ +D+G Y C+ATN +G S + R+I + + E+ P Sbjct: 2139 DRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIG----STSRRIIVDVEALKEA--P 2192 Query: 1416 SGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSN 1475 + K ++P FVT EG +V + CK+ + Sbjct: 2193 VFVSK---------------------LRPLFVT---------EGDNVSWMCKVAGMPRPT 2222 Query: 1476 LKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 VEW+++ QP+ R++ D +L + + +D G+Y C N G+ S L Sbjct: 2223 --VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQ 2280 Query: 1536 CRSTTDIVRSTQNEAGLEQIQVLEDR-----SKYHRTDMV-----DEVTTQAPICTTSLK 1585 + + + ++ ++ E R S R ++ +V + LK Sbjct: 2281 VDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELK 2340 Query: 1586 N-VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLP 1644 V ++E +F+ R+ T + WY + + ++ RF + S Sbjct: 2341 EPVVVQESDAINFKVRVRGKPVPT--IVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASA 2398 Query: 1645 EDSGTYTCRAINALGE 1660 ED+GTYTC A N LG+ Sbjct: 2399 EDAGTYTCEASNKLGK 2414 Score = 64.5 bits (150), Expect = 2e-09 Identities = 78/331 (23%), Positives = 129/331 (38%), Gaps = 36/331 (10%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 PE DI D EG E +I G +EWF + + + R Sbjct: 4849 PEVAEKMTDI-DAVEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTST 4905 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHI-QNIEGLKDGQS 3166 L I T D+G Y TN+ G + L ++ G P F + ++ ++ Sbjct: 4906 LVIRNCTTNDTGPYKVIGTNECGIGGAVLNLIIHEREFG--PEFIDEEGEYVKVVRSEGV 4963 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226 A+ TV +P ++ WY +G + +TR+ T S L+I + D+G Y+C A Sbjct: 4964 ANITFTVR--GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEA 5021 Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286 +K G+ F ++ V E + + K ++ AQ + Sbjct: 5022 RSKLGKCFRSCILDVQA---VPKEEVDHGQIVKPVITRKIRDAQGE-------------- 5064 Query: 3287 QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILY 3346 EG + FE + P VEW+ KL HG +Y+ G L I Sbjct: 5065 ---------EGSNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITG 5113 Query: 3347 CYEENSGEYECVATNKLGRDSTKANLKCTSK 3377 ++++G Y+ VATN+ G +++A + K Sbjct: 5114 VQKDDTGSYKVVATNQAGSSTSRAEVVVKDK 5144 Score = 63.3 bits (147), Expect = 5e-09 Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 14/236 (5%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F+ L+ + EG + + ++ + PT +EW ++ Q + A +R+ F SL Sbjct: 2192 PVFVSKLRPLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSL 2249 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE----- 751 + + +D G Y C ++ G A + A L V +A + + +Q ++ E Sbjct: 2250 FLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDV 2309 Query: 752 DYSKYQHQESIEEQTS---QRPQFI--RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806 +S E + S + +F L++ +QE +F+ ++ PT + W Sbjct: 2310 RFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPT--IVW 2367 Query: 807 YKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 YKDG + R + AEDAG+YT A NKLG+ ++ V Sbjct: 2368 YKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHV 2423 Score = 62.9 bits (146), Expect = 6e-09 Identities = 101/425 (23%), Positives = 162/425 (38%), Gaps = 83/425 (19%) Query: 1019 KIQYLEDASRYSKRTEEEV-KITQKPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTM 1075 K+ DA S + +V + KP L +K K VEG A F ++ P D Sbjct: 1386 KVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDV-KGVEGDEATFNVKLSGYPSPD--- 1441 Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 +EWY+ +I R + D +L I + +D G Y +A N AG+ A + V Sbjct: 1442 -IEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEV 1500 Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195 + R D + I EE +F+EP+ EI +PV V + Sbjct: 1501 KER---DYAPI----------FEEKQFLEPL----EIQVRQPVEV-------------SY 1530 Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255 H+ G P V W+ NG+ + G + + L I+ + D G Y A Sbjct: 1531 HVR------GRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLAR 1584 Query: 1256 NHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSR 1315 N +GSA R+ E +E ++ E+A + T Q+R Sbjct: 1585 NDVGSAE-----RLF-----------EVQVEGVKPKEEAPKLTSQLR------------- 1615 Query: 1316 ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSV 1375 + E + L C ++ D + EW + KP+K +++ L+ V Sbjct: 1616 ---SARITESDDFELACDVKGTPDPS--YEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRV 1670 Query: 1376 YPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL--ILES-QHPSGLE--KIQYLEDTSRY 1430 D G YT N G +S L ++ K ILE+ + G+E K ++ Y Sbjct: 1671 QLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSKPEILETMKDAEGIETGKAKFDVKIKAY 1730 Query: 1431 KKTDI 1435 K ++ Sbjct: 1731 PKAEV 1735 Score = 62.5 bits (145), Expect = 8e-09 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 3/98 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 + P TT + + ++G+ L V +PN ++EWFK+G L RL +F+ + Sbjct: 728 ETPTITTEMTDI-QAIDGEDCKLICHVTG--EPNPEVEWFKDGKPLKANHRLVPSFEERM 784 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 + LS ++ +D G Y C +N+ G S A +K+EDR Sbjct: 785 IALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822 Score = 62.5 bits (145), Expect = 8e-09 Identities = 66/293 (22%), Positives = 122/293 (41%), Gaps = 16/293 (5%) Query: 1541 DIVRSTQNEAGLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFER 1599 +I ++T ++AG + R +VD E +AP+ + L+ + + EG + Sbjct: 2154 EIRKATLDDAGTYICKATNSIGSTSRRIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMC 2213 Query: 1600 RLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 ++ + T VEWY +N+PL++ +R+ + +L + +D G Y C N+ G Sbjct: 2214 KVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAG 2271 Query: 1660 EAVTSGIAIVHSK--KSIYLESQH-----EGALPRLN-QLEDTSKYQRHSAQDEVITQAP 1711 A +S V K K +E + EG R + + + + ++ + + Sbjct: 2272 SAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNE 2331 Query: 1712 VF--TMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 F +K+ + V E+ A +F+ R+ G P + W ++G + R Sbjct: 2332 KFYGDDELKEPVVVQESDAINFKVRV--RGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIY 2389 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKI 1821 + ED+GTYTC A N+LG+ L V +S LQ + Sbjct: 2390 TFATYSASAEDAGTYTCEASNKLGKCSRDFNLHVDVPKEQWEAPSFKSQLQPV 2442 Score = 62.5 bits (145), Expect = 8e-09 Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 5/134 (3%) Query: 1675 IYLESQHEG--ALPRLNQLEDTS-KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFE 1731 ++ +S+H G + ++L +TS K+ E +AP F + E F Sbjct: 5210 LFTKSEHAGTYSCEATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLLPQNAREGDVVKFS 5269 Query: 1732 ARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINEL 1791 ++ G P+ +EW R+GV +E+ R+TT +D + L++ N DSG Y C N Sbjct: 5270 CKV--TGYPEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNS 5327 Query: 1792 GEAVTSSTLFVQSK 1805 G A +S+ L V K Sbjct: 5328 GWASSSAELVVGGK 5341 Score = 62.5 bits (145), Expect = 8e-09 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 9/189 (4%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR-TVYAFGMV 3106 PE K I + EG A ++ L+ TG ++W+ I +R T+ + GM Sbjct: 5640 PEINEKLKKI-EAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMA 5696 Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTH-IQNIEGLKDGQ 3165 L I + D G Y C A N++G+ V L +K G P F + + + G+ Sbjct: 5697 SLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEKHYG--PEFAEEELDWSKTARKGE 5754 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 +A TV PD + WY +G + +T + S L I + D+G YVC Sbjct: 5755 NARITFTVSGNPRPD--VVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCE 5812 Query: 3226 AYNKYGEDF 3234 A ++ G+ F Sbjct: 5813 AQSRLGKSF 5821 Score = 62.1 bits (144), Expect = 1e-08 Identities = 51/192 (26%), Positives = 82/192 (42%), Gaps = 8/192 (4%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P FTT K I D++EG+ + + + S + W+ N I R RT + Sbjct: 1903 PSFTTTLKPI-DVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETYK 1959 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L + K D+G Y C A+N G+A + ++ V+K + KP + E + +G +A Sbjct: 1960 LILQDIKIKDAGQYECIASNPIGKAFCTAEMT-VNKRE-VKPVIKEVSKTFE-VSEGGTA 2016 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 E V V P +EWYH + R + + + L I + + Y C A+ Sbjct: 2017 SIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAASYKCVAF 2074 Query: 3228 NKYGEDFTRATI 3239 N G RA + Sbjct: 2075 NNAGRTTYRADL 2086 Score = 62.1 bits (144), Expect = 1e-08 Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 18/239 (7%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 ++VE K +P FV++LR V EG + C+V + P +E+Y + + L++ R+ Sbjct: 2183 VDVEALKEAPV-FVSKLR-PLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRW 2238 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 + FD SL + +D G Y+ N+ G S+ + V K + ++ ++ Sbjct: 2239 KMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQ 2298 Query: 2352 KIRELESAEPFKRPEIPEP-VTRQR---PVFTQPLQNIDN------IQEGQTAHFDCRLI 2401 + E+ + +P P VT R V + D +QE +F R+ Sbjct: 2299 TVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRV- 2357 Query: 2402 PVGDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 G P + W+++ +++ D R ++ Y T S ED G Y C ASN LG+ Sbjct: 2358 -RGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYS-ASAEDAGTYTCEASNKLGK 2414 Score = 62.1 bits (144), Expect = 1e-08 Identities = 59/218 (27%), Positives = 98/218 (44%), Gaps = 18/218 (8%) Query: 3707 VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAG 3766 V EG V + C+V + PT ++W+ + +P +R D +L + +D G Sbjct: 2203 VTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKG 2260 Query: 3767 EYTCRATNKWGSATTTAKITC--SAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEE- 3823 Y C TN GSA ++A++ A + V+E ++ + E + R S P+ E Sbjct: 2261 VYNCVITNSAGSAFSSAELQVDKKANKPKVIE-KMNDVQTVEGTEARFDVRFSGLPRPEV 2319 Query: 3824 -----PIVSTPPKFI--TQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875 I KF ++K V+ES+ + F+ RV K P I WY++G+++ Sbjct: 2320 TWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVP--TIVWYKDGEMVRDV 2377 Query: 3876 HRYRTVYDMGFVSLDILY-VYAEDSGEYICRAVNDFGE 3912 R+ + G + Y AED+G Y C A N G+ Sbjct: 2378 RRFE-IRSRGDIYTFATYSASAEDAGTYTCEASNKLGK 2414 Score = 62.1 bits (144), Expect = 1e-08 Identities = 69/256 (26%), Positives = 101/256 (39%), Gaps = 42/256 (16%) Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048 +T G+ ++L T+ P V WY +G + + L IL+ +E G Sbjct: 5161 ITRGNQLNLNVTIR--GKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAG 5218 Query: 2049 TYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQR 2108 TY C+AT+ +G +S K D + IQ E PK Sbjct: 5219 TYSCEATSKLGN----TSAKFDVQ---------------IQAPEA--APKA--------- 5248 Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P FL L +N +EGD F C+V +P I+W +G + + R T +D + Sbjct: 5249 PAFLKQLLP-QNAREGDVVKFSCKVTGYPEPE--IEWTRDGVSMESDERVTTWYDGEHST 5305 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ-G 2227 L I DSG Y C N G A ++ L V G TQ P + +++L A G Sbjct: 5306 LSIHNANHADSGMYKCTLKNNSGWASSSAELVVGG------KTQRPRLSDNMKELFATVG 5359 Query: 2228 HSTRIEVEEPKISPPR 2243 R EV P+ Sbjct: 5360 GEARFEVTMKATPKPK 5375 Score = 61.7 bits (143), Expect = 1e-08 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 2/94 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 + P + + +I+ ++G + L C + G+ VEWF +GKP+K HR P++E + Sbjct: 728 ETPTITTEMTDIQAIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMI 785 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 AL + ED G Y C +N G ++ ++V Sbjct: 786 ALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKV 819 Score = 61.3 bits (142), Expect = 2e-08 Identities = 46/207 (22%), Positives = 84/207 (40%), Gaps = 12/207 (5%) Query: 383 IEISEKALAPQFVKV--CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440 + + E+ P+F++ ++ G + G P P V W+ D + D Sbjct: 3372 LTVKERLFGPEFLEEEGVWNKVAKAGGFVNISFTLKGNPRPHVVWY-RDGILLYDTTRMD 3430 Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-------IEKEQVVAPKF 493 + + H + I +TL D+G C AR++ G C L + E++++ Sbjct: 3431 IRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRSCTLEIKVPSMGGPEEKKISKALI 3490 Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI--HTDGGASTLDIP 551 + + + EG V R G P P + W + + + + + +I + G +L + Sbjct: 3491 GQGDNDVQAVEGWKVQFQTRITGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVN 3550 Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578 D Y+C A N AGS+A R L Sbjct: 3551 DVTKDDIGTYKCLATNSAGSSACRINL 3577 Score = 60.5 bits (140), Expect = 3e-08 Identities = 52/198 (26%), Positives = 86/198 (43%), Gaps = 12/198 (6%) Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104 G P F + + I +I+EG ++ S TG ++WF + I+ S R + Y Sbjct: 1018 GDTPTFMSKLEPI-EITEGD--DFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGN 1074 Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 + L + + D G Y C TN +G +S K + K +P + ++ ++ G Sbjct: 1075 VSALTVKEAELDDDGVYKCVVTNNFG--SVSSKADVTVLKKHLRPEVLQKMDDVRTVEGG 1132 Query: 3165 QSAHFECTVVPVDD-PDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQNHDSGE 3221 + A+F V +D P +IEWY + R IKT + +L I + D+G Sbjct: 1133 K-ANF---AVKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGT 1188 Query: 3222 YVCRAYNKYGEDFTRATI 3239 C A N G+ RA + Sbjct: 1189 VKCSATNAAGKTVVRADL 1206 Score = 60.5 bits (140), Expect = 3e-08 Identities = 68/263 (25%), Positives = 104/263 (39%), Gaps = 40/263 (15%) Query: 1701 SAQDEVITQA--PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758 SA+ +VI + P MKD++ E A F +L G P +EW I R Sbjct: 1399 SAKLKVIRKCTKPEVLEKMKDVKGVEGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGR 1456 Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818 D +L +K +N +D GTY C A NE G+ V +A L+++ + + + Sbjct: 1457 YKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGK--------VTQRAELEVKERDYAPI 1508 Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878 + +Q + Q R+ VEV+ Y R P P V Sbjct: 1509 FEEKQFLEPLEIQVRQPVEVS------------------------YHVRGRPKP----TV 1540 Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938 W+ NGK L+ G + + L IL ED+G Y C A N++G A + V+ Sbjct: 1541 TWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVEG 1600 Query: 1939 KESIIRDSQHESALEKIQYLEDD 1961 + + S L + E D Sbjct: 1601 VKPKEEAPKLTSQLRSARITESD 1623 Score = 60.5 bits (140), Expect = 3e-08 Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 6/174 (3%) Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128 E S G + W+ NGK + + L IL ++ D+G+Y C A N Sbjct: 1527 EVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARND 1586 Query: 3129 WGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWY 3186 G AE V++E V K K + P+ T+ +++ + +S FE PD EW Sbjct: 1587 VGSAERLFEVQVEGV-KPKEEAPKLTSQLRS---ARITESDDFELACDVKGTPDPSYEWL 1642 Query: 3187 HNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240 + +P++ + + D L+ Q D G Y N +G ++ A ++ Sbjct: 1643 KDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLD 1696 Score = 60.5 bits (140), Expect = 3e-08 Identities = 57/203 (28%), Positives = 87/203 (42%), Gaps = 39/203 (19%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFG-FIALDIDYIYARDAGEYTCRATNKWGSATT 3781 G P+ + W+ + R G R H L G + + A DAG Y C A N+ G Sbjct: 1829 GKPSPDVSWYRDDRLLLDG-RKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVG---- 1883 Query: 3782 TAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841 SA R+ +E ++P+ ++E P F T +K V Sbjct: 1884 ------SATRNFNVEIEVPKA------------------RDEA-----PSFTTTLKPIDV 1914 Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRN-GKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900 E E F CRV + +P + WYRN +++P G R RT +D L + + +D+G Sbjct: 1915 TEGENHTFICRVHARPEPS--VTWYRNKNEIVPDG-RSRTTFDGETYKLILQDIKIKDAG 1971 Query: 3901 EYICRAVNDFGEDFTKATISCKK 3923 +Y C A N G+ F A ++ K Sbjct: 1972 QYECIASNPIGKAFCTAEMTVNK 1994 Score = 60.5 bits (140), Expect = 3e-08 Identities = 41/115 (35%), Positives = 56/115 (48%), Gaps = 5/115 (4%) Query: 3676 EETLHKREEITIED--EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH 3733 +ET + +I IED + P F ++ ++DV E F C V G P RI WF Sbjct: 4434 KETTSQLFDIHIEDVCKSALAPGFKSALR-SLDVTEDESAEFRCEVS--GSPAPRIQWFM 4490 Query: 3734 NGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788 N +P + SR+ T +D L I +D G Y C A N GSAT+TA + S Sbjct: 4491 NDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNVS 4545 Score = 60.5 bits (140), Expect = 3e-08 Identities = 44/149 (29%), Positives = 69/149 (46%), Gaps = 9/149 (6%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP FT P++ I + E F + G P VEW R+ P+ +RL T D V Sbjct: 5543 APAFTAPLQHIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829 L ++ N D+G + C N+LG +S++L V S + + L+KI+ E Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNEGYS---KPEINEKLKKIEAFEGG-- 5655 Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSE 1858 + R D+ V PR + G TK+++ Sbjct: 5656 -EARFDLLVTGFPPPR-VDWYRGTTKITD 5682 Score = 60.1 bits (139), Expect = 4e-08 Identities = 65/254 (25%), Positives = 98/254 (38%), Gaps = 21/254 (8%) Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY 3101 +D PE T +D D E + A + +G IEWF I R Sbjct: 820 EDRSLKPEVITSMRDC-DCVEEETASFHCEF--SGKPEPEIEWFCGPNPIVPGGRFHVTE 876 Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161 + L I K D+G Y C A+N G+ +L+ +K P F I+ L Sbjct: 877 EGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEKHFA--PEFEDWKDTIDAL 934 Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS--TRIKTVSDFGFVVLDIAYTQNHDS 3219 DGQ + V P +I W +G+ +R++ +IK D +VL D+ Sbjct: 935 -DGQDVNISTWV--RGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVL--YKVSPEDA 989 Query: 3220 GEYVCRAYNKYG---EDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPST 3276 G Y CRA N G +D T T+ K G P ++K+ +E +G Q Sbjct: 990 GMYTCRAKNNAGIVSKDVT-ITVEALQKKGD-----TPTFMSKLEPIEITEGDDFQLSCN 1043 Query: 3277 PSAEPPKFITQIQD 3290 + P + +D Sbjct: 1044 VTGRPQPEVQWFRD 1057 Score = 59.7 bits (138), Expect = 6e-08 Identities = 42/183 (22%), Positives = 75/183 (40%), Gaps = 7/183 (3%) Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 AP F Q + EG V G+P P + W +D + + H++ G Sbjct: 2432 APSFKSQLQPVILEEGGTGVLVGEVAGKPLPTIQWMKDDYPVL--FGHRVRPQFDGRTCK 2489 Query: 451 MI-TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 +I + D G+ C+ +N+ GE + + + V V P+ +E+ + L + EG Sbjct: 2490 VIFREALIGDGGMYECIIKNQCGEASSKALVGV--NRGTVGPEIIEKPAGLVIVEGNDSR 2547 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG--GASTLDIPRAKASDAAWYQCTAQN 567 + R G PTP + W + + RI ++ G +L + + + Y+ A N Sbjct: 2548 FDVRIRGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTGHYRIVASN 2607 Query: 568 VAG 570 G Sbjct: 2608 EHG 2610 Score = 59.7 bits (138), Expect = 6e-08 Identities = 59/230 (25%), Positives = 92/230 (40%), Gaps = 37/230 (16%) Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 R E+ ++D+ P + I + G ++ + + G P + W+ +G T Sbjct: 5136 RAEVVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIR--GKPKPSVVWYKDGNKILTS 5193 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801 V + L I + + AG Y+C AT+K G+ SAK D+ + Q P+ Sbjct: 5194 RNVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNT--------SAKFDVQI--QAPE 5243 Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861 APK P F+ Q+ E + V+F C+V +P+ Sbjct: 5244 A----------------APKA-------PAFLKQLLPQNAREGDVVKFSCKVTGYPEPE- 5279 Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 IEW R+G + S R T YD +L I DSG Y C N+ G Sbjct: 5280 -IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSG 5328 Score = 59.3 bits (137), Expect = 8e-08 Identities = 122/559 (21%), Positives = 204/559 (36%), Gaps = 67/559 (11%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 PEF + I + A RL + V W+ +G L ++K L Sbjct: 379 PEFADGDLEPIEVKEDQA-VNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHEL 437 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV--KGRQGIILEPQLPSHFKSGTESIQKL 3675 I D G Y C+A+N G + K+ V KG +I +P + T + + Sbjct: 438 SIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSV 497 Query: 3676 EETLHKREEITIE----------------DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRV 3719 TL E ++ + P F +++D + E V F+ + Sbjct: 498 NTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVED-VTALETEQVWFEIPI 556 Query: 3720 EPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG 3777 + G P ++W+ G R + + +L ID D+G Y C A+N G Sbjct: 557 Q--GYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAG 614 Query: 3778 SATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG----RISDAPKEE--------PI 3825 TTA + V++ + + + ++K E I PK + P+ Sbjct: 615 K--TTALLNLDVNEK-VVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDLVPL 671 Query: 3826 VSTPPKFITQI-KSHTVE------ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878 + T + + HT+E + EG +++C K R + P G Sbjct: 672 LETRSIQLKSVGDEHTLEIINATPDDEG-KYKCEATNKAGTAFRSFDIKVKVAEPQGETP 730 Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938 +M DI + ED + IC GE + P VP + Sbjct: 731 TITTEM----TDIQAIDGEDC-KLICHVT---GEPNPEVEWFKDGKPLKANHRLVPSFEE 782 Query: 3939 RSEALT----QME--ATIKKYTSEVYLTEDDLYDV---DKKQPPRFVTQIQSQTSLVEME 3989 R AL+ ++E K S V+ + +V D+ P +T ++ VE E Sbjct: 783 RMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRSLKPEVITSMRD-CDCVEEE 841 Query: 3990 TTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCR 4049 T F C+ + G P ++EWF P++ RF + ++ + ED+G Y C Sbjct: 842 TASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCV 899 Query: 4050 ATNLYGMDETKAVIKTTGK 4068 A+N G T+A +K K Sbjct: 900 ASNAAGKTTTRAELKVNEK 918 Score = 59.3 bits (137), Expect = 8e-08 Identities = 66/269 (24%), Positives = 112/269 (41%), Gaps = 46/269 (17%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 + P F ++ E+TEG L +T P V+W+ + ++ RFK +YD Sbjct: 1019 DTPTFMSKLEPIEITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFKASYDGNVS 1076 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 AL + A +D G Y C TN G + + V V L+K+ Sbjct: 1077 ALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV---------------------LKKHL 1115 Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155 RP+ +++ + + ++ G +A+F +++ P I+W+ KI G Sbjct: 1116 RPEVLQK------------MDDVRTVEGG-KANFAVKIDAFPKPE--IEWYLGATKITDG 1160 Query: 2156 HRYRTTHD---FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQ 2212 R++ D Y+ L I +D+GT C ATN G+ V L+V +N+ Sbjct: 1161 GRFKIKTDKENCSYI-LFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVE-EKNVAPSFH 1218 Query: 2213 HPNGLEKIRQLEAQGHSTRIEVE-EPKIS 2240 G ++R E + S E+ +PK S Sbjct: 1219 GRQG--RLRVKEGREASVYFEISGKPKPS 1245 Score = 59.3 bits (137), Expect = 8e-08 Identities = 95/369 (25%), Positives = 148/369 (40%), Gaps = 46/369 (12%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G+ V W KDG + ++R+ T L I S+T DAG Y C A + +G+ S Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031 Query: 997 ANLTI--VTKKDII-AESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPR---FLGPLK 1050 L + V K+++ + P KI+ + + R E VK P + G +K Sbjct: 5032 CILDVQAVPKEEVDHGQIVKPVITRKIRDAQGEEGSNIRFEIHVKSHPPPHVEWYRGSIK 5091 Query: 1051 GTN----KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIA 1106 + +I EG A+ Q D T + + + +S +R + +A +A Sbjct: 5092 LAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDKPLAPKVA 5151 Query: 1107 SVRAEDSGVYTVVARNAA-------GEAQLSA-----------SMTVETRSSID------ 1142 + A +G T+ N G+ + S S V+ RS D Sbjct: 5152 EMTA--TGPITITRGNQLNLNVTIRGKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLII 5209 Query: 1143 --TSSIHRGLY--EKTRHI--EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196 T S H G Y E T + +KF + Q E + P F++ L P EG + Sbjct: 5210 LFTKSEHAGTYSCEATSKLGNTSAKF-DVQIQAPEAAPKAPAFLKQLL-PQNAREGDVVK 5267 Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256 C++ G P +EW +G S+ R T+YD L I +A AD+G Y N Sbjct: 5268 FSCKVT--GYPEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKN 5325 Query: 1257 HLGSAHTSA 1265 + G A +SA Sbjct: 5326 NSGWASSSA 5334 Score = 58.8 bits (136), Expect = 1e-07 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 3/114 (2%) Query: 2624 AAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGV 2683 A N E+ V +AP FTT LK D + EG++ +V R +P+ + W++N Sbjct: 1885 ATRNFNVEIEVPKARDEAPSFTTTLKPID-VTEGENHTFICRVHARPEPS--VTWYRNKN 1941 Query: 2684 TLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 + R ++TFD L + ++ D+G Y C A+N +G+A TA + + R Sbjct: 1942 EIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995 Score = 58.8 bits (136), Expect = 1e-07 Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 3/98 (3%) Query: 904 ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN 963 E P F T + +S+ EG + F A + G ++W KD P+ ++ RI TFF+ Sbjct: 3977 EKWSSPIFVTELSP-LSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFD 4033 Query: 964 FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 V L I +T+ D G Y N G AT+SA L++ Sbjct: 4034 GHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071 Score = 58.8 bits (136), Expect = 1e-07 Identities = 54/204 (26%), Positives = 89/204 (43%), Gaps = 31/204 (15%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 G+P + W+ +G + +R+ T + L+I + + DAG Y C A +K G Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCF-- 5029 Query: 3783 AKITCSAKRDIVLESQ-LPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841 R +L+ Q +P+ +E++ G+I +P+++ +I+ Sbjct: 5030 --------RSCILDVQAVPK-------EEVDHGQIV-----KPVITR------KIRDAQG 5063 Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGE 3901 EE +RFE V K P +EWYR L G +Y+ G SL I V +D+G Sbjct: 5064 EEGSNIRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGS 5121 Query: 3902 YICRAVNDFGEDFTKATISCKKLP 3925 Y A N G ++A + K P Sbjct: 5122 YKVVATNQAGSSTSRAEVVVKDKP 5145 Score = 58.8 bits (136), Expect = 1e-07 Identities = 37/113 (32%), Positives = 52/113 (46%), Gaps = 3/113 (2%) Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886 S+++ + A +AP F+ QL P EG + C++ YP+P +EW +G Sbjct: 5232 SAKFDVQIQAPEAAPKAPAFLKQLL-PQNAREGDVVKFSCKVTGYPEPE--IEWTRDGVS 5288 Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 ++S R T D + L I DSG Y C NN G A SS L V K Sbjct: 5289 MESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK 5341 Score = 58.8 bits (136), Expect = 1e-07 Identities = 48/160 (30%), Positives = 67/160 (41%), Gaps = 14/160 (8%) Query: 3399 TLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYW 3458 T V V E+ AP FT PL +I+ L EG+ F +T P VEWY Sbjct: 5523 TAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDIL-EGDTTRFIGEITGVPVP--VVEWYR 5579 Query: 3459 NGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518 + + + R RT+ D VIL + T D+G + C N+ G ++AS+ V Sbjct: 5580 DDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVN----- 5634 Query: 3519 ILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPP 3558 E + + KI A EG D L +G PP Sbjct: 5635 --EGYSKPEINEKLKKIEAFEGGEARFDLLV----TGFPP 5668 Score = 58.4 bits (135), Expect = 1e-07 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 3/95 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +AP T+ LK DK+ EG+ V + P I W+K+G + R+K +FD Sbjct: 183 KAPTVTSELKP-DKVQEGEQYKFTCAVTGKPKP--VISWYKDGQPIKADRRVKDSFDGTT 239 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 TL I ++ DD G Y + TN LG STA +++ Sbjct: 240 STLLIKDVKQDDKGTYKVEITNDLGSISSTADLEV 274 Score = 58.4 bits (135), Expect = 1e-07 Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 3/104 (2%) Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471 V E +G+ P T +++I+ + +GE+ +T +PN +VEW+ +GK LKA R Sbjct: 722 VAEPQGETPTITTEMTDIQAI-DGEDCKLICHVT--GEPNPEVEWFKDGKPLKANHRLVP 778 Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 + + L P ED G Y C N +G + A +KV+ + Sbjct: 779 SFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822 Score = 58.4 bits (135), Expect = 1e-07 Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F S L ++ E ++ F C V S P +I+WF N++P+ +R ++ D L I Sbjct: 4457 FKSALRSLDVTEDESAEFRCEVSGS--PAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAI 4514 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 T +D+G+Y C A N GSAT++ L Sbjct: 4515 TKATLQDTGVYKCLAVNDNGSATSTADL 4542 Score = 58.0 bits (134), Expect = 2e-07 Identities = 85/401 (21%), Positives = 156/401 (38%), Gaps = 37/401 (9%) Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872 Q + K++ D D+EV A + + + EG A +E + + YP Sbjct: 249 QDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFKGYP 308 Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930 P + EW+ + K ++ R++ + D ++L I + +DSG Y C A N G+ Sbjct: 309 IP--KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGEC-- 364 Query: 1931 SIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVT 1990 ++R +++ K + LE I+ ED + R + KP+ ++ Sbjct: 365 NLRADLKVKNKPFAPEFADGDLEPIEVKEDQAVNVRLTVTGN---PKPEVTWYKDGTQLH 421 Query: 1991 EGHPVHLEAT------LTPVNDPTMRVEWYCN-GRPVQQGHR-FKTTYDFGYVALDILYA 2042 + + L+AT P +++C P+ R FK T VA I Sbjct: 422 DTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVI--- 478 Query: 2043 YAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEE 2102 ++G + G + ++ DA E ++K E+ I Sbjct: 479 ---ESGLMPLQVRKETGAKWSVNTTLDDA---------GEYKVKVTNEVGSVTSLADINV 526 Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY--RT 2160 ++ +P FL + + L E ++ FE ++ P ++W+ +I+ G R+ Sbjct: 527 QKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQ--GYPRPIVEWYRGTTRIKDGGRFTISE 583 Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + + +L I EDSG Y C A+N G+ L V Sbjct: 584 SEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDV 624 Score = 58.0 bits (134), Expect = 2e-07 Identities = 50/184 (27%), Positives = 74/184 (40%), Gaps = 6/184 (3%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 PE KD+ + EG A + L +G S IEW+Y I R + Sbjct: 1411 PEVLEKMKDVKGV-EGDEATFNVKL--SGYPSPDIEWYYGTTRIRDGGRYKFSRDDQKYS 1467 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I D GTY C A+N+ G+ +LE K + P F Q +E L+ Sbjct: 1468 LTIKDLNLQDIGTYKCIASNEAGKVTQRAELEV--KERDYAPIFEEK-QFLEPLEIQVRQ 1524 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 E + P + W+ NG+ +R ++ S + L I ++ D+G Y C A Sbjct: 1525 PVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLAR 1584 Query: 3228 NKYG 3231 N G Sbjct: 1585 NDVG 1588 Score = 58.0 bits (134), Expect = 2e-07 Identities = 53/207 (25%), Positives = 91/207 (43%), Gaps = 32/207 (15%) Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXX 2594 +G+P W+ +GV+L SR L+I + +DAG Y+C+A +R G Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236 Query: 2595 XXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKL 2654 +A+RP ++Q + +K+ + Sbjct: 4237 SCTLDV--------KAVRPRRGNEVQACKPQTSKMANVTA-------------------- 4268 Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF--DFGLVTLSINSLRNDDS 2712 VEG V L+ ++ P +EWF+ +T G R K+ D GL +L I+ ++ +DS Sbjct: 4269 VEGWKVQLDTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDS 4326 Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHW 2739 G Y A+N LGEA + A + ++ +H+ Sbjct: 4327 GSYRAVASNNLGEATTLAELTVKGKHF 4353 Score = 57.6 bits (133), Expect = 2e-07 Identities = 76/291 (26%), Positives = 123/291 (42%), Gaps = 31/291 (10%) Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 R ++ +++ KP P F + I+V E V+ R+ G+P + W+ +G Sbjct: 367 RADLKVKN-KPFAPEFADGDLEPIEVKEDQAVNV--RLTVTGNPKPEVTWYKDGTQLHDT 423 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI-VLESQL- 3799 ++ L I D G+Y C A+N GS T K+T K V+ES L Sbjct: 424 KKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLM 483 Query: 3800 PQGM----------------SGE-KIKEL-ERGRISD-APKEEPIVSTPPKFITQIKSHT 3840 P + +GE K+K E G ++ A P+F+ +++ T Sbjct: 484 PLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVT 543 Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY--RTVYDMGFVSLDILYVYAED 3898 E+E V FE ++ P+ +EWYR + G R+ + SL I ED Sbjct: 544 ALETEQVWFEIPIQGY--PRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTED 601 Query: 3899 SGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949 SG Y C A ND G+ T A ++ + + ++Q + + +K E EAT Sbjct: 602 SGPYKCVASNDAGK--TTALLNL-DVNEKVVQPEFDKEVKPIEVKHGEEAT 649 Score = 57.6 bits (133), Expect = 2e-07 Identities = 54/229 (23%), Positives = 97/229 (42%), Gaps = 10/229 (4%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F+++++ V E + V + C+V P+ +EWYR+ + L + R++ +D SL Sbjct: 2192 PVFVSKLRPLFVTEGDNVSWMCKVAGM--PRPTVEWYRDNQPLRADTRWKMDFDGRVCSL 2249 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949 + +D G Y C N G F+ A + K + + +V M + + EA Sbjct: 2250 FLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKAN---KPKVIEKMNDVQTVEGTEAR 2306 Query: 3950 IKKYTSEVYLTEDDLY-DVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008 S + E Y + K + +F + + +V E+ ++ G P + Sbjct: 2307 FDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIV 2366 Query: 4009 WFFNGKPLLHKNRFTPIYDFG--YVAMNFGWVYPEDSGEYLCRATNLYG 4055 W+ +G+ + RF I G Y + ED+G Y C A+N G Sbjct: 2367 WYKDGEMVRDVRRF-EIRSRGDIYTFATYS-ASAEDAGTYTCEASNKLG 2413 Score = 57.2 bits (132), Expect = 3e-07 Identities = 33/106 (31%), Positives = 56/106 (52%), Gaps = 3/106 (2%) Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894 +V A ++AP F T L P ++EG++ + CR+ P+P+ V WY N + R R Sbjct: 1894 EVPKARDEAPSFTTTLK-PIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSR 1950 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 T+ D L + + +D+G+Y C A N +G+A + + V +E Sbjct: 1951 TTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKRE 1996 Score = 57.2 bits (132), Expect = 3e-07 Identities = 43/198 (21%), Positives = 78/198 (39%), Gaps = 8/198 (4%) Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118 ++SEG A E + +G +EW++ + R + L I + Sbjct: 2009 EVSEGGTASIEVKV--SGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAA 2066 Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178 +Y C A N G+ + + + V + P F + +++GQ+A T+ Sbjct: 2067 ASYKCVAFNNAGRT--TYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTIRARPS 2124 Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR-- 3236 PD +EWY + +I + G L+I D+G Y+C+A N G R Sbjct: 2125 PD--VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRII 2182 Query: 3237 ATINCYGKGGVYLESLQP 3254 + + V++ L+P Sbjct: 2183 VDVEALKEAPVFVSKLRP 2200 Score = 57.2 bits (132), Expect = 3e-07 Identities = 65/250 (26%), Positives = 94/250 (37%), Gaps = 14/250 (5%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P+F + V +EG + V + PK +EW+++GK L R L Sbjct: 3129 PEFDEEESPKPVIVNEGEEAQMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYL 3188 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949 I +V ED G Y C A + G +S K+P + +P + L +E Sbjct: 3189 VIYHVTPEDEGSYKCVASSTNGRSSRTFDLSV-KVPKPKDKWSLPAFSSKLRPLETLEGE 3247 Query: 3950 IKKYTSEVY-----LTEDDLYDVDKKQPPRFVTQIQSQT-SLVEMETTKFECQLAPV--- 4000 K+ V E D K RF T + LV +T FEC A + Sbjct: 3248 KTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAH 3307 Query: 4001 --GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDE 4058 G P VEWF L R+ + ++ ED+G Y ATN +G Sbjct: 3308 VAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHG--S 3365 Query: 4059 TKAVIKTTGK 4068 T +V+ T K Sbjct: 3366 TGSVVDLTVK 3375 Score = 57.2 bits (132), Expect = 3e-07 Identities = 80/344 (23%), Positives = 132/344 (38%), Gaps = 41/344 (11%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140 + WF+ I + R + L I G + GTY C ATN G+ V C Sbjct: 3814 VTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTYKCIATNDAGK----VTAHCH 3869 Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 +D +K + E + + P +EW+ +GQ + ++ + Sbjct: 3870 LDVTKQDFAPIVAGSEMPEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHL 3929 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260 + + LD+ T DSG Y A N G + +N + ++ P Sbjct: 3930 RARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNLN--------VTAIAPKE---- 3977 Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320 + +P + P +T+ D TK V AH +P ++W+ Sbjct: 3978 ---------KWSSPIFVTELSPLSVTE-GDYTKFV----AHVSGVPLP------SIQWYK 4017 Query: 3321 NGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380 + + HR RTF D +V L I E+ G+Y+ V N+ G ++ A L + Sbjct: 4018 DDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGK 4077 Query: 3381 ILDSQLPRGMEG--GLEKLQTLEDSMVRRKDTSVEEEKGKAPVF 3422 +QL R +EG G E T++ S V + VE +GK +F Sbjct: 4078 PAITQLYRDVEGFDGSESELTVQVSGVPAAE--VEWFRGKTKLF 4119 Score = 57.2 bits (132), Expect = 3e-07 Identities = 65/233 (27%), Positives = 95/233 (40%), Gaps = 36/233 (15%) Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028 QD + +V + +PI V EG V + A + PT VEW+ +G+ + + Sbjct: 3875 QDFAPIVAGSEMPEPIV---VREGCEVSMMANVRGKPAPT--VEWFKDGQLLSNTNNLHL 3929 Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKI 2088 Y LD+L D+GTY ATN +G A ++ V A I Sbjct: 3930 RARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTA----------------I 3973 Query: 2089 QELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHN 2148 EK+ P +F+T L+ L ++ EGD F V + P +I W+ + Sbjct: 3974 APKEKWSSP------------IFVTELSPL-SVTEGDYTKFVAHVSGV--PLPSIQWYKD 4018 Query: 2149 GQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 I + HR RT D V L I ED G Y N+ G A ++ L V Sbjct: 4019 DNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071 Score = 56.8 bits (131), Expect = 4e-07 Identities = 46/181 (25%), Positives = 73/181 (40%), Gaps = 7/181 (3%) Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118 D++EG + +G +EW N + + + R +T + L I D+ Sbjct: 1325 DVTEGDDCRLTCKV--SGYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADA 1382 Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178 Y N G+ S KL+ + K KP +++++G+ +G A F + Sbjct: 1383 VPYKVVVRNDAGEVSSSAKLKVIRKCT--KPEVLEKMKDVKGV-EGDEATFNVKLSGYPS 1439 Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRAT 3238 PD IEWY+ +R R K D L I D G Y C A N+ G+ RA Sbjct: 1440 PD--IEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAE 1497 Query: 3239 I 3239 + Sbjct: 1498 L 1498 Score = 56.8 bits (131), Expect = 4e-07 Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 10/144 (6%) Query: 3376 SKENL-ILDSQLPRGMEGGLEKLQTL----EDSMVRRKDTS--VEEEKGKAPVFTVPLSN 3428 S++N+ L P +GGL K E SM+ D V EE AP F + L+ Sbjct: 4702 SRDNVYFLRFARPSVKDGGLYKCVATNEHGEASMLFNLDVEGHVPEEDWSAPSFVIELTP 4761 Query: 3429 IENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPE 3488 + EGE+ E +T T P KVEW+ N K +K R++ D + L + T E Sbjct: 4762 T-TVTEGESTALEVEITGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLE 4818 Query: 3489 DSGEYLCRAYNNYGEAVTTASMKV 3512 D+G Y C N+ G A + A + V Sbjct: 4819 DAGLYRCTILNDLGTASSMADLSV 4842 Score = 56.8 bits (131), Expect = 4e-07 Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 5/115 (4%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P F P+++ ++ EG +T V P VEWY + RPV + HR +T D V L Sbjct: 5544 PAFTAPLQHIDILEGDTTRFIGEITGVPVPV--VEWYRDDRPVTRDHRLRTYSDGRVVIL 5601 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092 + D G + C N +G +++S+ V+ G ++E +LKKI+ E Sbjct: 5602 LLRQTNISDAGVFKCVLRNDLGTVASSASLNVN--EGYSKPEINE-KLKKIEAFE 5653 Score = 56.4 bits (130), Expect = 5e-07 Identities = 60/239 (25%), Positives = 88/239 (36%), Gaps = 12/239 (5%) Query: 3034 KEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA 3093 KEP DT P + V K D ++ + IEWF + Sbjct: 2719 KEPKSVDSTDTRAPGQLIPV-KHKFDFEGVPGGKARCDVLVKKSDIIDIEWFRGTNMLRD 2777 Query: 3094 SHRIRTVYAFGMVVLEILGTKTT--DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF 3151 + + + + L ++ D+GTY C GQ I +L K K Q P F Sbjct: 2778 GDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHI--KEKQQAPLF 2835 Query: 3152 TTHIQNIE--GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVL 3209 + E L GQ + TV P I WY +G+P+ + RI S L Sbjct: 2836 LDEKVSQEKFSLPQGQEMNKSFTVT--GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYL 2893 Query: 3210 DIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG---KGGVYLESLQPDSLAKIRELES 3265 I + D+G Y C A N+ G + ++ KG SL+ +A I E +S Sbjct: 2894 GILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPKVKGEAPSFSLELRPIAAIEEFDS 2952 Score = 56.4 bits (130), Expect = 5e-07 Identities = 70/354 (19%), Positives = 137/354 (38%), Gaps = 22/354 (6%) Query: 46 RQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSW 105 R T E S + +P I E+ ++ G +AKF ++ G P P V+W Sbjct: 3758 RCTATNQEGSTSSSAVIVVNRASITPRIIEKP-RDVDAVDGTDAKFTVRVEGFPQPKVTW 3816 Query: 106 TRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI--- 161 + +V +Y + + GD+ SL+I+ + G Y C A N G+ ++ Sbjct: 3817 FHESTKIVSRGRYEI---SRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVT 3873 Query: 162 -QPEGXXXXXXXXXXXXXYRHVSE-TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTD 219 Q R E ++ G T E + Q ++ TN + Sbjct: 3874 KQDFAPIVAGSEMPEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARG 3933 Query: 220 DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEI-DRSLGPVSP------PKIAQKP 272 ++ F LL+ +S T ++V +D+ + I + ++ ++P P + Sbjct: 3934 EY----FNLDLLKTTQ-ADSGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTEL 3988 Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332 + EG +F +SG P P + W+K+ + ++++ + L + D Sbjct: 3989 SPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLED 4048 Query: 333 SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386 G Y ++ +N +G +S L+V Q + + E+E +++S Sbjct: 4049 QGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVEGFDGSESELTVQVS 4102 Score = 56.0 bits (129), Expect = 7e-07 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840 ++QEG F +T P + WYKDG+PI A R+ F+ +L I ++ +D Sbjct: 195 KVQEGEQYKFTCAVTGKPKPV--ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDK 252 Query: 841 GSYTVRAVNKLGEAISTASIRVAAR 865 G+Y V N LG STA + V + Sbjct: 253 GTYKVEITNDLGSISSTADLEVTPK 277 Score = 56.0 bits (129), Expect = 7e-07 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 3/97 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P F + L+ + + EG L V R P +++WF++ V + R K+++D + Sbjct: 1021 PTFMSKLEPIE-ITEGDDFQLSCNVTGRPQP--EVQWFRDEVLIKPSRRFKASYDGNVSA 1077 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738 L++ DD G+Y C TN G S A + + +H Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH 1114 Score = 56.0 bits (129), Expect = 7e-07 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 4/103 (3%) Query: 764 EQTSQRPQFI--RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 ++ Q P F+ + Q+ L +G+ + T PT + WYKDG P+ + RI Sbjct: 2827 KEKQQAPLFLDEKVSQEKFSLPQGQEMN--KSFTVTGSPTPHITWYKDGEPLDDTRRIDI 2884 Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864 L I++L+ EDAG+YT A N++G A + + V A Sbjct: 2885 RSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTA 2927 Score = 56.0 bits (129), Expect = 7e-07 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 2/94 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 +AP FS L I +E + L C + G +++W NGKP+++ R R Y+ Sbjct: 2933 EAPSFSLELRPIAAIEEFDSKLICHVS--GKPKPQIKWTKNGKPVESDGRLRTDYDGIVA 2990 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + V +D+G Y C A+N G +S AL V Sbjct: 2991 YLSIWQVSHDDAGTYECIASNAAGTVSSSAALTV 3024 Score = 56.0 bits (129), Expect = 7e-07 Identities = 48/192 (25%), Positives = 79/192 (41%), Gaps = 8/192 (4%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P F + + + D++E + A + + +G + I+WF N + + RI T + Sbjct: 4455 PGFKSALRSL-DVTEDESAEFRCEV--SGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I D+G Y C A N G A + L V + KP F ++ + + G+ A Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLN-VSHCR-MKPTFVERLREVTTVFGGE-A 4568 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 F V P KI WY + + + R + L I DSG Y+C Sbjct: 4569 SFSVRVKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILS 4626 Query: 3228 NKYGEDFTRATI 3239 N G++ R+ + Sbjct: 4627 NAVGKETCRSQL 4638 Score = 56.0 bits (129), Expect = 7e-07 Identities = 30/109 (27%), Positives = 55/109 (50%), Gaps = 3/109 (2%) Query: 2629 VPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688 VP+ VD G P+ T ++ EG ++ E V+ P+ +EW++ + L G Sbjct: 5039 VPKEEVDHGQIVKPVITRKIRDAQG-EEGSNIRFEIHVKSHPPPH--VEWYRGSIKLAHG 5095 Query: 2689 ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 + + + G +L+I ++ DD+G Y ATN G + S A + ++D+ Sbjct: 5096 PKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDK 5144 Score = 55.6 bits (128), Expect = 9e-07 Identities = 68/253 (26%), Positives = 100/253 (39%), Gaps = 28/253 (11%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F P V E + +++ RL G+P V W+ +G + + K Sbjct: 379 PEFADGDLEPIEVKEDQAVNV--RLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHE 436 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTS--------AIVRVIERSDIVTDTQNEQAIEQI 1288 L I A++ D G+Y A N LGS + + VIE + + E + Sbjct: 437 LSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWS 496 Query: 1289 --QLLEDAAR-RTKQVRE--------DITVMQA---PQFSRALHNIETVEGTNVHLECRL 1334 L+DA + K E DI V +A P+F R + ++ +E V E + Sbjct: 497 VNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPI 556 Query: 1335 QPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392 Q G VEW+ IK G RF + E D +L + EDSG Y C A+N G Sbjct: 557 Q--GYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAG 614 Query: 1393 EAVTSCALRVIAK 1405 + L V K Sbjct: 615 KTTALLNLDVNEK 627 Score = 55.6 bits (128), Expect = 9e-07 Identities = 86/387 (22%), Positives = 156/387 (40%), Gaps = 76/387 (19%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 KP+ + +K+ + EG L+ P +EWY ++ G R+K + D + Sbjct: 1410 KPEVLEKMKDVKGVEGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKYS 1467 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096 L I +D GTY C A+N G+ T +++ K Y +E++ + E++ + Sbjct: 1468 LTIKDLNLQDIGTYKCIASNEAGK--VTQRAELEVKERDYAPIFEEKQFLEPLEIQ-VRQ 1524 Query: 2097 PKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156 P + G+ +T + + L++G H E IR+G Sbjct: 1525 PVEVSYHVRGRPKPTVTWWKNGKELRDG--KHVE---------------------IRSGG 1561 Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNG 2216 Y T L IL + ED+G+Y C A N +G A Sbjct: 1562 TYHT--------LYILRSEEEDAGSYKCLARNDVGSA----------------------- 1590 Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276 E++ +++ +G + + E PK++ ++LR + + E C V+ DP+ Sbjct: 1591 -ERLFEVQVEG--VKPKEEAPKLT-----SQLR-SARITESDDFELACDVKGTPDPS--Y 1639 Query: 2277 EFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336 E+ + K ++ +FD +L+ + D G Y+V NA G S+ ++ Sbjct: 1640 EWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANL---- 1695 Query: 2337 KGSIISESQRPEGLEKIRELESAEPFK 2363 I+ +PE LE +++ E E K Sbjct: 1696 --DIVKSKSKPEILETMKDAEGIETGK 1720 Score = 55.6 bits (128), Expect = 9e-07 Identities = 82/367 (22%), Positives = 138/367 (37%), Gaps = 25/367 (6%) Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705 + EG ++ + G P +EW K+GQ + ++ R Y +LD+L D Sbjct: 3890 IVVREGCEVSMMANVR--GKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQAD 3947 Query: 706 SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE----DYSKY-QHQE 760 SG Y A + G A L+VT A E+ S P + + L DY+K+ H Sbjct: 3948 SGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSS-PIFVTELSPLSVTEGDYTKFVAHVS 4006 Query: 761 SIEEQTSQRPQFIRPLQDLGELQEGRNAH----FEAQLTPVSDPTMRVEWYKDGRPITAS 816 + + Q + P+ ++ + H Q+T +V + T+S Sbjct: 4007 GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSS 4066 Query: 817 SRITSIFNFGYVSLNIMHLRAED-AGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875 ++++ +G ++ ++ E GS + V G + A + T P Sbjct: 4067 AKLSVREEYGKPAITQLYRDVEGFDGSESELTVQVSG--VPAAEVEWFRGKTKL----FP 4120 Query: 876 EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEF-KTPIKDQISIKEGGFAHFEARLE 934 +R Y V E PEF + K ++E GFA+ + Sbjct: 4121 SERSY---KIIATNEYGRTGALIDLTVKERLFGPEFIEEDGKWSKIVRERGFANITFMV- 4176 Query: 935 PIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQAT 994 +G+ V W KDG + +SR+ L I +T DAG Y C A + +G Sbjct: 4177 -LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCF 4235 Query: 995 TSANLTI 1001 S L + Sbjct: 4236 RSCTLDV 4242 Score = 55.2 bits (127), Expect = 1e-06 Identities = 71/297 (23%), Positives = 114/297 (38%), Gaps = 39/297 (13%) Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997 K +P + WY +G +L +R + S +++ + D+G Y C+A ++ G A Sbjct: 3407 KGNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIR 3466 Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI 3057 S CT L + G E E + K Q D+D Sbjct: 3467 S----CT----LEIKVPSMGGPE--------EKKISKALIGQGDND-------------- 3496 Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS--HRIRTVYAFGMVVLEILGTKT 3115 V EG ++ + TG +EW+ + S ++I G+ L + Sbjct: 3497 VQAVEGWKVQFQTRI--TGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTK 3554 Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQSAHFECTVV 3174 D GTY C ATN G + + L+ DK P H E + +GQ + + VV Sbjct: 3555 DDIGTYKCLATNSAGSSACRINLDVKDKQYA--PEIPGHEDRQELNVPEGQEINMD--VV 3610 Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 P +++ WY +G+ ++ + RI S L I DSG Y C + G Sbjct: 3611 IKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLYKCEGVSTLG 3667 Score = 55.2 bits (127), Expect = 1e-06 Identities = 46/195 (23%), Positives = 80/195 (41%), Gaps = 9/195 (4%) Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096 G P++D P F ++EG+ E + TG +EWF N K ++ H Sbjct: 4743 GHVPEEDWSAP-SFVIELTPTT-VTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDHL 4798 Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ 3156 +R+ + ++ L + T D+G Y C N G A L V+++ KP + Sbjct: 4799 VRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLS-VNRAL-TKPEVAEKMT 4856 Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216 +I+ + +G E V+ P K+EW+ + + ++ R L I Sbjct: 4857 DIDAV-EGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCTT 4913 Query: 3217 HDSGEYVCRAYNKYG 3231 +D+G Y N+ G Sbjct: 4914 NDTGPYKVIGTNECG 4928 Score = 55.2 bits (127), Expect = 1e-06 Identities = 52/204 (25%), Positives = 83/204 (40%), Gaps = 31/204 (15%) Query: 2000 TLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059 T T +P V WY +G + R T L+I +ED GTYMC+A + +G Sbjct: 4967 TFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLG 5026 Query: 2060 EAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQ--RPVFLTALTS 2117 + + LD Q + K EE GQ +PV + Sbjct: 5027 KCFRSC-------------ILDVQAVPK-------------EEVDHGQIVKPVITRKIRD 5060 Query: 2118 LENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE 2177 + +EG FE V+ PH ++W+ K+ G +Y+ + G +L I + Sbjct: 5061 AQG-EEGSNIRFEIHVKSHPPPH--VEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKD 5117 Query: 2178 DSGTYMCKATNKLGEAVNTCTLKV 2201 D+G+Y ATN+ G + + + V Sbjct: 5118 DTGSYKVVATNQAGSSTSRAEVVV 5141 Score = 54.8 bits (126), Expect = 2e-06 Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P F L IE EG + L C + G V+WF + IK RF+ +Y+ + AL Sbjct: 1021 PTFMSKLEPIEITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 1078 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408 + +D GVY C TN G +V+S A + KK L Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFG-SVSSKADVTVLKKHL 1115 Score = 54.8 bits (126), Expect = 2e-06 Identities = 50/207 (24%), Positives = 81/207 (39%), Gaps = 13/207 (6%) Query: 383 IEISEKALAPQFVKVCQ--DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440 + + E+ P+F++ + V E V G P P V WF + Q+ + + Sbjct: 4142 LTVKERLFGPEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDM 4201 Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI-------EKEQVVAPKF 493 +S + L I +T D+G C AR++ G C L+V + Q P+ Sbjct: 4202 RSRDSLQY-LNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKAVRPRRGNEVQACKPQ- 4259 Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI--HTDGGASTLDIP 551 + + + EG V L+ R G P P + W + I + D G +L I Sbjct: 4260 TSKMANVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIIS 4319 Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578 + D+ Y+ A N G T A L Sbjct: 4320 DVQLEDSGSYRAVASNNLGEATTLAEL 4346 Score = 54.8 bits (126), Expect = 2e-06 Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 12/157 (7%) Query: 3117 DSGTYSCRATNKWGQAEISVKLEC---VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173 D G Y C ATN+ G+A + L+ V + P F + + +G+S E + Sbjct: 4718 DGGLYKCVATNEHGEASMLFNLDVEGHVPEEDWSAPSFVIELTPTT-VTEGESTALEVEI 4776 Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233 P K+EW+ N +P++H +++ D + L + T D+G Y C N G Sbjct: 4777 TGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTA 4834 Query: 3234 FTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQ 3270 + A ++ V +P+ K+ ++++++G + Sbjct: 4835 SSMADLS------VNRALTKPEVAEKMTDIDAVEGTE 4865 Score = 54.8 bits (126), Expect = 2e-06 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 3/94 (3%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP F+ +L PT ++EG+S E I P P +VEW+ N K ++ H R+ D Sbjct: 4752 APSFVIELT-PTTVTEGESTALEVEITGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVI 4808 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 L + ED+G Y C +N+LG A S L+V Sbjct: 4809 RLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842 Score = 54.8 bits (126), Expect = 2e-06 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 3/91 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P F+ ++ T + EG+S E + P KVEWF N K + H H R++ D ++ Sbjct: 4753 PSFVIELTPTT-VTEGESTALEVEITGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVIR 4809 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372 L + E++G Y C N LG S+ A+L Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMADL 4840 Score = 54.8 bits (126), Expect = 2e-06 Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 11/147 (7%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F L ++ L EGD F + + P ++W+ + + + HR RT D V Sbjct: 5544 PAFTAPLQHIDIL-EGDTTRFIGEITGVPVP--VVEWYRDDRPVTRDHRLRTYSDGRVVI 5600 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA-QG 2227 L + T D+G + C N LG ++ +L N+ P EK++++EA +G Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASL------NVNEGYSKPEINEKLKKIEAFEG 5654 Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHV 2254 R ++ PPR V RGTT + Sbjct: 5655 GEARFDLLVTGFPPPR-VDWYRGTTKI 5680 Score = 54.4 bits (125), Expect = 2e-06 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP F ++ + V E+++A F + G P R++W N P+ +R+ T D Sbjct: 4454 APGFKSALRSLDVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 L + +D+G Y C A+N+ G A +++ L V Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 54.4 bits (125), Expect = 2e-06 Identities = 52/200 (26%), Positives = 84/200 (42%), Gaps = 28/200 (14%) Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932 +P V WY +G +L R T + L+I ++ ED+G Y C+A + LG+ Sbjct: 4973 NPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCF--- 5029 Query: 1933 RLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEG 1992 S I D Q A+ K + D + KP + I++A+ EG Sbjct: 5030 -------RSCILDVQ---AVPKEEV-------------DHGQIVKPVITRKIRDAQGEEG 5066 Query: 1993 HPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMC 2052 + E + + P VEWY + G +++ + G +L I +DTG+Y Sbjct: 5067 SNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKV 5124 Query: 2053 KATNAVGEAVTTSSVKVDAK 2072 ATN G + + + V V K Sbjct: 5125 VATNQAGSSTSRAEVVVKDK 5144 Score = 54.0 bits (124), Expect = 3e-06 Identities = 66/247 (26%), Positives = 96/247 (38%), Gaps = 30/247 (12%) Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643 L+ +E+KE Q + RL + +V WY + L + L I Sbjct: 386 LEPIEVKEDQAVNV--RLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKAS 443 Query: 1644 PEDSGTYTCRAINALGE--------AVTSGIAIVHSKKSIYLESQHE-GALPRLNQ-LED 1693 D G Y C A N LG V G+A V + L+ + E GA +N L+D Sbjct: 444 TNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDD 503 Query: 1694 TSKYQRH---------SAQDEVITQA---PVFTMPMKDIRVAENQAAHFEARLIPV-GDP 1740 +Y+ S D + +A P F ++D+ E + FE IP+ G P Sbjct: 504 AGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFE---IPIQGYP 560 Query: 1741 KLRVEWLRNGVPIEASNRLTTMH--DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798 + VEW R I+ R T + +L + EDSG Y C A N+ G+ Sbjct: 561 RPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALL 620 Query: 1799 TLFVQSK 1805 L V K Sbjct: 621 NLDVNEK 627 Score = 54.0 bits (124), Expect = 3e-06 Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 3/114 (2%) Query: 753 YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812 + + + + E + P + D+ + +G + +T +P VEW+KDG+P Sbjct: 713 FRSFDIKVKVAEPQGETPTITTEMTDIQAI-DGEDCKLICHVT--GEPNPEVEWFKDGKP 769 Query: 813 ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866 + A+ R+ F ++L+ ++ ED G Y N G S A ++V RS Sbjct: 770 LKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS 823 Score = 54.0 bits (124), Expect = 3e-06 Identities = 30/88 (34%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836 I+ + + C E + F C E S P +IEWF P+ G R+ T + + SL I+ Sbjct: 829 ITSMRDCDCVEEETASFHC--EFSGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAIS 886 Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLR 2864 ED+G Y C A+N+ G TT L+ Sbjct: 887 DLKLEDAGNYKCVASNAAGKTTTRAELK 914 Score = 54.0 bits (124), Expect = 3e-06 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P F L+ I+ I EG C + G P +V+WFR+E LI+ S R ++D + Sbjct: 1021 PTFMSKLEPIE-ITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 1077 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 +T+ +D+GVY C +N G Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFG 1100 Score = 54.0 bits (124), Expect = 3e-06 Identities = 65/260 (25%), Positives = 113/260 (43%), Gaps = 27/260 (10%) Query: 907 QKPEFKTPIKDQISIKEGGFAHFEARL--EPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964 + P F ++ +I+E F+++L G +++W K+G+PVE+ R+ T ++ Sbjct: 2933 EAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYD- 2986 Query: 965 GYVA-LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYL 1023 G VA L+I V+ DAG Y C A NA G ++SA LT V+++++ H L Sbjct: 2987 GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALT-VSRRNMRPLITHK--------L 3037 Query: 1024 EDASRY-SKRTEEEVKITQKPR-FLGPLKGTNKIVEGQSAHFEARVEP------QSDLTM 1075 D Y K ++++T P + KG + I EG+ + E SDL Sbjct: 3038 HDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNA 3097 Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 + + A + T +A D E+ V+ N EAQ+ S+ Sbjct: 3098 DDDGIYKCVAQNLAGKASTRAMLDVIARDFGPEFDEEESPKPVIV-NEGEEAQMMVSVRG 3156 Query: 1136 ETRSSIDTSSIHRGLYEKTR 1155 ++ ++ + LY+ R Sbjct: 3157 RPKAVVEWFKDGKFLYDSRR 3176 Score = 54.0 bits (124), Expect = 3e-06 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP F + L ++E +SA + C + P P R++W+ N + + R TS+D Sbjct: 4454 APGFKSALRS-LDVTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPVH 4510 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 L I +D+G Y C A+N+ G A S+ LNV Sbjct: 4511 KLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 54.0 bits (124), Expect = 3e-06 Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 29/199 (14%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G+P ++ W K+G + ++R + R L++ SL +D+G Y C A S G Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031 Query: 724 AVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQ 783 +L V +A + H + + +P R ++D + + Sbjct: 5032 CILDV--QAVPKEEVDHGQIV------------------------KPVITRKIRD-AQGE 5064 Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843 EG N FE + S P VEWY+ + + G SL I ++ +D GSY Sbjct: 5065 EGSNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSY 5122 Query: 844 TVRAVNKLGEAISTASIRV 862 V A N+ G + S A + V Sbjct: 5123 KVVATNQAGSSTSRAEVVV 5141 Score = 54.0 bits (124), Expect = 3e-06 Identities = 56/200 (28%), Positives = 84/200 (42%), Gaps = 28/200 (14%) Query: 2138 DPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197 +P + W+ +G + R T L+I +ED+GTYMC+A +KLG+ +C Sbjct: 4973 NPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSC 5032 Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEG 2257 ILD Q + K E H ++ +P I+ R + + +G EG Sbjct: 5033 ----------ILDVQ---AVPK----EEVDHG---QIVKPVIT--RKIRDAQGE----EG 5066 Query: 2258 KTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSV 2317 FE V+ H P +E+Y L ++ I+ G SL I +D G Y V Sbjct: 5067 SNIRFEIHVKS-HPPP-HVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKV 5124 Query: 2318 KAINALGHCTSAISMTVTAK 2337 A N G TS + V K Sbjct: 5125 VATNQAGSSTSRAEVVVKDK 5144 Score = 54.0 bits (124), Expect = 3e-06 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 3/93 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P F PLQ + ++ EG F ++T V P VEWY+D RP+T R+ + + V Sbjct: 5544 PAFTAPLQHI-DILEGDTTRFIGEITGVPVPV--VEWYRDDRPVTRDHRLRTYSDGRVVI 5600 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 L + DAG + N LG S+AS+ V Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633 Score = 53.6 bits (123), Expect = 4e-06 Identities = 24/66 (36%), Positives = 34/66 (51%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066 P +EW+C P+ G RF T + +L I ED G Y C A+NA G+ T + Sbjct: 853 PEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAE 912 Query: 2067 VKVDAK 2072 +KV+ K Sbjct: 913 LKVNEK 918 Score = 53.6 bits (123), Expect = 4e-06 Identities = 59/255 (23%), Positives = 108/255 (42%), Gaps = 41/255 (16%) Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ---APQFSRALHNIETVEGTNVHLEC 1332 ++D + E A + +AA +T R ++ V + AP+F I+ ++G +V++ Sbjct: 885 ISDLKLEDAGNYKCVASNAAGKTT-TRAELKVNEKHFAPEFEDWKDTIDALDGQDVNIST 943 Query: 1333 RLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392 ++ G + W +G+ ++ + D L L V PED+G+YTC+A N G Sbjct: 944 WVR--GKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAG 1001 Query: 1393 EAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKS 1452 I KD+ + +E +Q DT P F+++ + Sbjct: 1002 ----------IVSKDVTIT------VEALQKKGDT----------------PTFMSKLEP 1029 Query: 1453 IENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512 IE + EG C + +V+WF++ + RF+ +D AL + + + Sbjct: 1030 IE-ITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELD 1086 Query: 1513 DSGIYTCRAVNLVGT 1527 D G+Y C N G+ Sbjct: 1087 DDGVYKCVVTNNFGS 1101 Score = 53.6 bits (123), Expect = 4e-06 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 2/88 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F+S L I EGD+ CNV P +++WF + + R+K+++D + +L + Sbjct: 1023 FMSKLEPIEITEGDDFQLSCNVTGRPQP--EVQWFRDEVLIKPSRRFKASYDGNVSALTV 1080 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 +D G+Y C TN+ GS ++ + Sbjct: 1081 KEAELDDDGVYKCVVTNNFGSVSSKADV 1108 Score = 53.6 bits (123), Expect = 4e-06 Identities = 75/334 (22%), Positives = 131/334 (39%), Gaps = 40/334 (11%) Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIE--ASHRIRTVYAFGMVVLEILGTKTTD 3117 I EG + ++ + G + +EWFY + + +RI + G+ L + + Sbjct: 2540 IVEGNDSRFDVRI--RGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597 Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHF-ECTVVPV 3176 +G Y A+N+ G+A+ + L ++ P F + E K + F T + Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTVNERLYA--PEFLE--DDGEWSKVVRKGGFVNITFTLM 2653 Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236 +P + WY +G + ++R S +I + D+G YVC A+N+ G F Sbjct: 2654 GNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRS 2713 Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296 TI +I+E +S+ + P KF D + V Sbjct: 2714 CTI-------------------EIKEPKSVDSTDTRAPGQLIPVKHKF-----DF-EGVP 2748 Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF--HDFGIVILDILYCYEENSGE 3354 G A + LV D + +EWF L G +Y+ D + L + E++G Sbjct: 2749 GGKARCDV-LVKKSD-IIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGT 2806 Query: 3355 YECVATNKLGRDSTKANLKCTSKEN--LILDSQL 3386 Y CV G+ + + L K+ L LD ++ Sbjct: 2807 YRCVVHTPAGQTTIRGELHIKEKQQAPLFLDEKV 2840 Score = 53.6 bits (123), Expect = 4e-06 Identities = 64/265 (24%), Positives = 104/265 (39%), Gaps = 34/265 (12%) Query: 3819 APKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878 APKE+ + P F+T++ +V E + +F V P I+WY++ + S HR Sbjct: 3974 APKEK---WSSPIFVTELSPLSVTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRI 4028 Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPR 3935 RT +D V L I + ED G+Y N+ G + A +S ++ P I + Sbjct: 4029 RTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVE 4088 Query: 3936 GMKRSEA----------------------LTQMEATIKKYTSEVYLTEDDLYDVDKKQ-- 3971 G SE+ L E + K + Y L D+ K+ Sbjct: 4089 GFDGSESELTVQVSGVPAAEVEWFRGKTKLFPSERSYKIIATNEYGRTGALIDLTVKERL 4148 Query: 3972 -PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030 P F+ + + S + E +G+P V WF +G L +R Sbjct: 4149 FGPEFIEE-DGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSL 4207 Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYG 4055 +N + P+D+G Y+C A + G Sbjct: 4208 QYLNIFGLTPDDAGTYVCEARSRLG 4232 Score = 53.6 bits (123), Expect = 4e-06 Identities = 61/260 (23%), Positives = 106/260 (40%), Gaps = 35/260 (13%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 +F++ L+ + EGD F +V S P I+W+ ++ P+ S R ++ D V L Sbjct: 3983 IFVTELSPLSVTEGDYTKFVAHV--SGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLL 4040 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGD------KNIYFDTQHPQGKAGLEAVE 2888 I ED G Y N GSAT+S L + +Y D + G V+ Sbjct: 4041 IGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVEGFDGSESELTVQ 4100 Query: 2889 ----QAEEARLAKGRR---PS------VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQ- 2934 A E +G+ PS + EY + +I + + +L + + +G+ Sbjct: 4101 VSGVPAAEVEWFRGKTKLFPSERSYKIIATNEYGRTGALIDLTVKERLFGPEFIEEDGKW 4160 Query: 2935 ---VEPK----------NDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 V + +P + W+ +G L + SR + S L++ + D+ Sbjct: 4161 SKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDA 4220 Query: 2982 GIYTCKAYNKRGEAFTSSTV 3001 G Y C+A ++ G F S T+ Sbjct: 4221 GTYVCEARSRLGTCFRSCTL 4240 Score = 53.6 bits (123), Expect = 4e-06 Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 3/100 (3%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V +S P FK+ ++ + + E A F R E G R++W + +PV SRI T Sbjct: 4448 VCKSALAPGFKSALRS-LDVTEDESAEF--RCEVSGSPAPRIQWFMNDQPVSRDSRIITS 4504 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 + L I T+ D G Y C A N G AT++A+L + Sbjct: 4505 SDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 53.6 bits (123), Expect = 4e-06 Identities = 48/156 (30%), Positives = 68/156 (43%), Gaps = 17/156 (10%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F +AL SL+ + E + A F C V P I WF N Q + R T+ D Sbjct: 4455 PGFKSALRSLD-VTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA--- 2225 L I +D+G Y C A N G A +T L V+ R P +E++R++ Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCR------MKPTFVERLREVTTVFG 4565 Query: 2226 --QGHSTRIE-VEEPKISPPRFVTEL--RGTTHVFE 2256 S R++ PKI + +T L RG H+ E Sbjct: 4566 GEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISE 4601 Score = 53.6 bits (123), Expect = 4e-06 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 2/92 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P F +++ +VTE ++ P R++W+ N +PV + R T+ D L Sbjct: 4455 PGFKSALRSLDVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKL 4512 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 I A +DTG Y C A N G A +T+ + V Sbjct: 4513 AITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 53.6 bits (123), Expect = 4e-06 Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 E KAP F L +N REG+ F ++T +P ++EW +G S+++ R T+ Sbjct: 5243 EAAPKAPAFLKQLLP-QNAREGDVVKFSCKVTGYPEP--EIEWTRDGVSMESDERVTTWY 5299 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 D L I DSG Y C NN G A ++A + V GK Sbjct: 5300 DGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK 5341 Score = 53.2 bits (122), Expect = 5e-06 Identities = 50/196 (25%), Positives = 86/196 (43%), Gaps = 36/196 (18%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 + W KDG+P++A R+ F+ L IK V D G Y N +G +++A+L + Sbjct: 216 ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVT 275 Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062 K A+ + +E ++ +E + + EVK P I + + H Sbjct: 276 PKP---AKPEVVRKMENVESVEGSDAFF-----EVKFKGYP-----------IPKREWFH 316 Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122 ++EP S +T + + +Q +S L I+ +R +DSG Y +A N Sbjct: 317 DSKKIEPSSRFKITTD---DTEQTSS--------------LVISDLRLDDSGAYQCIASN 359 Query: 1123 AAGEAQLSASMTVETR 1138 AGE L A + V+ + Sbjct: 360 EAGECNLRADLKVKNK 375 Score = 53.2 bits (122), Expect = 5e-06 Identities = 33/87 (37%), Positives = 47/87 (54%), Gaps = 5/87 (5%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 +P + ++N++++ EG A F+ + G P K EWF + K IE SSR T D Sbjct: 280 KPEVVRKMENVESV-EGSDAFFEVKF--KGYPIPKREWFHDSKKIEPSSRFKITTDDTEQ 336 Query: 2435 --SMTISHVRDEDEGVYMCRASNLLGE 2459 S+ IS +R +D G Y C ASN GE Sbjct: 337 TSSLVISDLRLDDSGAYQCIASNEAGE 363 Score = 53.2 bits (122), Expect = 5e-06 Identities = 68/267 (25%), Positives = 108/267 (40%), Gaps = 20/267 (7%) Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900 +E E R+ +PK + WY++G L + + L I D G Sbjct: 389 IEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEG 448 Query: 3901 EYICRAVNDFG--EDFTKATISCKKLPDIILQNQVP-RGMKRSEALTQMEATIK------ 3951 +Y C A N G + K T+ K + +I +P + K + A + T+ Sbjct: 449 QYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYK 508 Query: 3952 -KYTSEV-YLTEDDLYDVDK-KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008 K T+EV +T +V K K P F+ +++ T+L E E FE + G P VE Sbjct: 509 VKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQ--GYPRPIVE 565 Query: 4009 WFFNGKPLLHKNRFT--PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066 W+ + RFT + ++ EDSG Y C A+N G +T A++ Sbjct: 566 WYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAG--KTTALLNLD 623 Query: 4067 GKPGIVYDSQLPKHMKSIEKIREMEAS 4093 +V + K +K IE EA+ Sbjct: 624 VNEKVV-QPEFDKEVKPIEVKHGEEAT 649 Score = 53.2 bits (122), Expect = 5e-06 Identities = 27/85 (31%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F+SHLN++ EGD+ C + +PT +EWF +++ + + R +S+ + +L Sbjct: 3689 FLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTLIF 3746 Query: 2836 THTYEEDSGIYTCKATNSKGSATTS 2860 +D G Y C ATN +GS ++S Sbjct: 3747 ETVNIQDRGAYRCTATNQEGSTSSS 3771 Score = 53.2 bits (122), Expect = 5e-06 Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 13/162 (8%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P F T + ++EG + A + +G I+W+ + I ++HRIRT + G VV Sbjct: 3982 PIFVTELSPL-SVTEGDYTKFVAHV--SGVPLPSIQWYKDDNPISSNHRIRTFFD-GHVV 4037 Query: 3108 LEILGTKT-TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166 ++G T D G Y N+ G A S KL V + G KP T +++EG +S Sbjct: 4038 KLLIGQITLEDQGQYKVVLKNESGSATSSAKLS-VREEYG-KPAITQLYRDVEGFDGSES 4095 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQ---PMRHSTRIKTVSDFG 3205 E TV P ++EW+ P S +I +++G Sbjct: 4096 ---ELTVQVSGVPAAEVEWFRGKTKLFPSERSYKIIATNEYG 4134 Score = 53.2 bits (122), Expect = 5e-06 Identities = 80/359 (22%), Positives = 137/359 (38%), Gaps = 31/359 (8%) Query: 1077 VEWYFNGKQITSANRIQT--YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134 VEW+ ++IT R +T D G +L I+ V+ EDSG Y VA N GEA A +T Sbjct: 4288 VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELT 4347 Query: 1135 VETR---SSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSE 1191 V+ + ++ H L + + K + P + + I + ++ S Sbjct: 4348 VKGKHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHPKQVIWYKDGIRLEDSRRVNLRSV 4407 Query: 1192 GKNIHL---ECRLEPMG----DPTMRVEWFHNGRSVTVGSRFKTYYDFGFV----ALDII 1240 G+ ++ E G + T E + + K+ GF +LD+ Sbjct: 4408 GERYYVVVPSASFEDSGIYKCETTSEKETTSQLFDIHIEDVCKSALAPGFKSALRSLDVT 4467 Query: 1241 HATSAD-----TGEYTVRAVNHLGSAHTSAIVRVIERSD-------IVTDTQNEQAIEQI 1288 SA+ +G R + S R+I SD I T + + + Sbjct: 4468 EDESAEFRCEVSGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKC 4527 Query: 1289 QLLEDAARRTKQVREDIT-VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWF 1347 + D T +++ P F L + TV G R++ G ++ W+ Sbjct: 4528 LAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGEASFSVRVK--GFPRPKIVWY 4585 Query: 1348 CNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406 + + RF + E D L + +V +DSG Y C +N +G+ L V A++ Sbjct: 4586 KDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEE 4644 Score = 53.2 bits (122), Expect = 5e-06 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612 +S P F + L ++E+ SA F C + + R++WF N +P+ SR+ T +D Sbjct: 4450 KSALAPGFKSALRSLDVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDG 4507 Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 L I +D G+Y C A N +G AT + L V Sbjct: 4508 PVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 52.8 bits (121), Expect = 7e-06 Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 7/151 (4%) Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVN-QAPRFITQLNGPTKLSEGQSAHYE 1865 S+ + ++S K + R DV V V +AP ++L P K+ EG+ + Sbjct: 147 SIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELK-PDKVQEGEQYKFT 205 Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925 C + P P + WY +G+ +++ R + S D + L I V +D G Y + N+L Sbjct: 206 CAVTGKPKPV--ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDL 263 Query: 1926 GQAVSSIRLNV---QSKESIIRDSQHESALE 1953 G S+ L V +K ++R ++ ++E Sbjct: 264 GSISSTADLEVTPKPAKPEVVRKMENVESVE 294 Score = 52.8 bits (121), Expect = 7e-06 Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 2/98 (2%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 + P T M DI+ + + + G+P VEW ++G P++A++RL + + Sbjct: 728 ETPTITTEMTDIQAIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMI 785 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806 AL+ + + ED G Y C N G +++ + V+ ++ Sbjct: 786 ALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS 823 Score = 52.8 bits (121), Expect = 7e-06 Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 3/97 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+ + +++DV K VEG A F +L PD +EW+Y ++ G RY+ D Sbjct: 1411 PEVLEKMKDV-KGVEGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKYS 1467 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 L I ++ G Y+C+A+N+ G+ + +A L+ ++ Sbjct: 1468 LTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKERD 1504 Score = 52.8 bits (121), Expect = 7e-06 Identities = 50/238 (21%), Positives = 96/238 (40%), Gaps = 11/238 (4%) Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565 E P+F L P + EG + + +V + P++ EWY + L+ +R++ D Sbjct: 2190 EAPVFVSKLR-PLFVTEGDNVSWMCKVAGMPRPTV--EWYRDNQPLRADTRWKMDFDGRV 2246 Query: 2566 VTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXX---XIIDQAMRPESWEQIQLK 2622 +L ++ D G+Y C N AG +I++ ++ E + + Sbjct: 2247 CSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEAR 2306 Query: 2623 -EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVY----LEAQVEPRTDPNLKIE 2677 + + +P V + D+L E V + +V R P I Sbjct: 2307 FDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIV 2366 Query: 2678 WFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 W+K+G + R + + T + S +D+G YTC+A+N LG+ ++ ++ Sbjct: 2367 WYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHVD 2424 Score = 52.8 bits (121), Expect = 7e-06 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 3/117 (2%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 +EK +P+F LS + ++ EG+ F A ++ P+ ++WY + + + R RTF Sbjct: 3976 KEKWSSPIFVTELSPL-SVTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFF 4032 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530 D V L I ED G+Y N G A ++A + V+ + +QL + +EG Sbjct: 4033 DGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVEG 4089 Score = 52.8 bits (121), Expect = 7e-06 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 1/116 (0%) Query: 4085 EKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144 E E E + Q+ + + K+ P F S ++ V E E A F C V+G P PR+ W Sbjct: 4429 ETTSEKETTSQLFDIHIEDVCKSALAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQW 4488 Query: 4145 LLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199 +N + SR + DG H I K DTG + + L V Sbjct: 4489 FMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 52.8 bits (121), Expect = 7e-06 Identities = 36/121 (29%), Positives = 59/121 (48%), Gaps = 6/121 (4%) Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228 + E S P FV L+ P V+EG++ LE +E G P +VEWF N + V ++ Sbjct: 4745 VPEEDWSAPSFVIELT-PTTVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRS 4801 Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA---IVRVIERSDIVTDTQNEQAI 1285 Y+D + L + T D G Y +N LG+A + A + R + + ++ + A+ Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAV 4861 Query: 1286 E 1286 E Sbjct: 4862 E 4862 Score = 52.8 bits (121), Expect = 7e-06 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 2/94 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F+ ++ TV E E E VE P ++EW++N K + H R+ +D + L Sbjct: 4753 PSFVIELTPTTVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRL 4810 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 + ED+G Y C +ND G + A +S + Sbjct: 4811 IVRRTTLEDAGLYRCTILNDLGTASSMADLSVNR 4844 Score = 52.8 bits (121), Expect = 7e-06 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 2/93 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P F + VTEG LE +T P +VEW+ N +PV+ H ++ +D + L Sbjct: 4753 PSFVIELTPTTVTEGESTALEVEIT--GTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRL 4810 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 + ED G Y C N +G A + + + V+ Sbjct: 4811 IVRRTTLEDAGLYRCTILNDLGTASSMADLSVN 4843 Score = 52.8 bits (121), Expect = 7e-06 Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 10/143 (6%) Query: 903 PESTQK-PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 PE+ K P F + Q + +EG F ++ G +EW +DG +E+ R+TT+ Sbjct: 5242 PEAAPKAPAFLKQLLPQ-NAREGDVVKFSCKVT--GYPEPEIEWTRDGVSMESDERVTTW 5298 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021 ++ + L+I + D+G Y C N G A++SA L + K +Q P + ++ Sbjct: 5299 YDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK------TQRPRLSDNMK 5352 Query: 1022 YLEDASRYSKRTEEEVKITQKPR 1044 L R E +K T KP+ Sbjct: 5353 ELFATVGGEARFEVTMKATPKPK 5375 Score = 52.4 bits (120), Expect = 9e-06 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 14/122 (11%) Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF--KTTYDFGYVALDILYAYAE 2045 EV EG V+L+ T+T P V WY +G+P+++ K+T D + L I A Sbjct: 99 EVFEGESVNLDLTIT--GKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF--LSIPKATPN 154 Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE-------RPK 2098 D+G Y C+A N +G + V V K G E + K+QE E+Y+ +PK Sbjct: 155 DSGKYKCEAKNKIGTSARDFDVNVKVK-GKAPTVTSELKPDKVQEGEQYKFTCAVTGKPK 213 Query: 2099 PI 2100 P+ Sbjct: 214 PV 215 Score = 52.4 bits (120), Expect = 9e-06 Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 2/105 (1%) Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 +V E ++ P V S+ D VEE E A F C +G P+P + W N IV G R+ + Sbjct: 816 EVKVEDRSLKPEVITSMRDCDCVEE-ETASFHCEFSGKPEPEIEWFCGPNPIVPGGRFHV 874 Query: 4160 TYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRH 4203 T +G + I + D G + + LKV +H Sbjct: 875 TEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEKH 919 Score = 52.4 bits (120), Expect = 9e-06 Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 35/201 (17%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 V W+ N K L+ G + + L I+ ED+G+Y C A N +G Sbjct: 1540 VTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVG----------- 1588 Query: 1671 SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHF 1730 S + ++ E Q EG P+ +AP T ++ R+ E+ F Sbjct: 1589 SAERLF-EVQVEGVKPK--------------------EEAPKLTSQLRSARITESD--DF 1625 Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790 E G P EWL++ P++ L++ D LN K V D G+YT N Sbjct: 1626 ELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNA 1685 Query: 1791 LGEAVTSSTL-FVQSKASLQL 1810 G +S+ L V+SK+ ++ Sbjct: 1686 HGSTYSSANLDIVKSKSKPEI 1706 Score = 52.4 bits (120), Expect = 9e-06 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 3/101 (2%) Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693 V G + P F +HL S D + EG L ++ + +P +EWFK+ +T R++S Sbjct: 3679 VPDGSRVTPKFLSHLNSLD-VDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRS 3735 Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 + TL ++ D G Y C ATN G S+A I + Sbjct: 3736 SVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVV 3776 Score = 52.4 bits (120), Expect = 9e-06 Identities = 48/188 (25%), Positives = 73/188 (38%), Gaps = 14/188 (7%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P+F + + D+ EG A + G +EWF + + I + R+R+ Sbjct: 3687 PKFLSHLNSL-DVDEGDSAKLTCKMF--GKPEPTVEWFKDDQLITNNDRVRSSVVGNTCT 3743 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L D G Y C ATN+ G S + V PR ++++ + DG A Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVI--VVNRASITPRIIEKPRDVDAV-DGTDA 3800 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPM--RHSTRIKTVSD-FGFVVLDIAYTQNHDSGEYVC 3224 F TV P K+ W+H + R I V D + V+ + Y G Y C Sbjct: 3801 KF--TVRVEGFPQPKVTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLH---VGTYKC 3855 Query: 3225 RAYNKYGE 3232 A N G+ Sbjct: 3856 IATNDAGK 3863 Score = 52.4 bits (120), Expect = 9e-06 Identities = 62/228 (27%), Positives = 95/228 (41%), Gaps = 41/228 (17%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYV 2035 KP+ + +K E EG + +T P RV+WY + +R+ +T G Sbjct: 5639 KPEINEKLKKIEAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMA 5696 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 +L I ED G Y C A N GE T+S+ VD G EK+ Sbjct: 5697 SLTIRKIRQEDGGLYGCVAVNEYGE---TTSI-VDLHVG-----------------EKHY 5735 Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI-RA 2154 P+ EEE L + ++G+ A V +P + W+ +G + Sbjct: 5736 GPEFAEEE-----------LDWSKTARKGENARITFTVS--GNPRPDVVWYKDGMLLFDT 5782 Query: 2155 GH-RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 H R+ D Y L I +D+GTY+C+A ++LG++ T LKV Sbjct: 5783 THVDMRSRGDIQY--LTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKV 5828 Score = 52.4 bits (120), Expect = 9e-06 Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT-HDFGY 2433 +P + L+ I+ + G+ A FD L+ G P +V+W+R I D +R + T G Sbjct: 5639 KPEINEKLKKIEAFEGGE-ARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGM 5695 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459 S+TI +R ED G+Y C A N GE Sbjct: 5696 ASLTIRKIRQEDGGLYGCVAVNEYGE 5721 Score = 52.4 bits (120), Expect = 9e-06 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT-TMHDFGYVA 1769 P +K I E A F+ L+ G P RV+W R I NR + T+ G + Sbjct: 5640 PEINEKLKKIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMAS 5697 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 L ++ + ED G Y C A+NE GE + L V K Sbjct: 5698 LTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733 Score = 52.0 bits (119), Expect = 1e-05 Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 5/106 (4%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFN-GKVLQSGHRYRTSNDFGFAALDILTVYGEDSGE 1916 E A ++ IE YP P VEWY K+ SG +D G +L I + +D+G Sbjct: 4 ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61 Query: 1917 YTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962 Y C A N+ GQ +S+R ++ KE I E E I+ E +S Sbjct: 62 YKCVATNDAGQ--TSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGES 105 Score = 52.0 bits (119), Expect = 1e-05 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P+ ++ + + VE C G +EWFC PI G RF E + +L Sbjct: 826 PEVITSMRDCDCVEEETASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSL 883 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 + + ED+G Y C A+N G+ T L+V K Sbjct: 884 AISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 52.0 bits (119), Expect = 1e-05 Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 4/84 (4%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN--DFGFAALDILTVYGEDSG 1915 EG + R+ YP P VEW+ + + G RY+T+ D G +L I V EDSG Sbjct: 4270 EGWKVQLDTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSG 4327 Query: 1916 EYTCKAINNLGQAVSSIRLNVQSK 1939 Y A NNLG+A + L V+ K Sbjct: 4328 SYRAVASNNLGEATTLAELTVKGK 4351 Score = 52.0 bits (119), Expect = 1e-05 Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP F L EG + LE + G +VEWF N KP+K H R ++ + Sbjct: 4752 APSFVIELTPTTVTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIR 4809 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + ED+G+Y C N LG A + L V Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842 Score = 52.0 bits (119), Expect = 1e-05 Identities = 50/202 (24%), Positives = 84/202 (41%), Gaps = 29/202 (14%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G+P+ V W ++G + + R+ T LN+ + ED+GTY C Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMC------------ 5019 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857 +A +L S + +Q + +E+V+ P IT+ + Sbjct: 5020 -------EARSKLGKCFRSCILDVQAVP-------KEEVDHGQIVKP-VITRKIRDAQGE 5064 Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 EG + +E ++ +P P+ VEWY L G +Y+ S G +L I V +D+G Y Sbjct: 5065 EGSNIRFEIHVKSHPPPH--VEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSY 5122 Query: 1918 TCKAINNLGQAVSSIRLNVQSK 1939 A N G + S + V+ K Sbjct: 5123 KVVATNQAGSSTSRAEVVVKDK 5144 Score = 51.6 bits (118), Expect = 2e-05 Identities = 20/65 (30%), Positives = 36/65 (55%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G+ VEW KDG+P++A+ R+ F +AL+ + + + D G Y C N G +++ Sbjct: 755 GEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSA 814 Query: 997 ANLTI 1001 A + + Sbjct: 815 AEVKV 819 Score = 51.6 bits (118), Expect = 2e-05 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 2/94 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F+++++ + E + + C V + P+ ++W+R+ L+ R++ YD +L Sbjct: 1021 PTFMSKLEPIEITEGDDFQLSCNVTGRPQPE--VQWFRDEVLIKPSRRFKASYDGNVSAL 1078 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 + +D G Y C N+FG +KA ++ K Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLK 1112 Score = 51.6 bits (118), Expect = 2e-05 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSA--NRIQTYHDFGYVALDIASVRAED 1112 IVEG + F+ R+ T VEW++ +++T RI++ + G +L ++ V+ + Sbjct: 2540 IVEGNDSRFDVRIRGHP--TPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597 Query: 1113 SGVYTVVARNAAGEAQLSASMTVETR 1138 +G Y +VA N G+AQ +TV R Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTVNER 2623 Score = 51.6 bits (118), Expect = 2e-05 Identities = 55/211 (26%), Positives = 87/211 (41%), Gaps = 33/211 (15%) Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 TVEW+ +G+ +++ N + Y LD+ DSG Y VA N G A ++ V Sbjct: 3911 TVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNLNV 3970 Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195 T + K+ P++ + E+S PLS V+EG Sbjct: 3971 ------------------TAIAPKEKWSSPIF-VTELS--------PLS----VTEGDYT 3999 Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255 + G P ++W+ + ++ R +T++D V L I T D G+Y V Sbjct: 4000 KFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLK 4057 Query: 1256 NHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286 N GSA +SA + V E TQ + +E Sbjct: 4058 NESGSATSSAKLSVREEYGKPAITQLYRDVE 4088 Score = 51.6 bits (118), Expect = 2e-05 Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 7/135 (5%) Query: 1006 DIIAESQHPGGLEKIQYLED-ASRYSKRTEEEVKITQKPRFLGPLKGTN----KIVEGQS 1060 D++ +Q G K D S Y I K ++ P+ T + EG Sbjct: 3939 DLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTELSPLSVTEGDY 3998 Query: 1061 AHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVA 1120 F A V +++WY + I+S +RI+T+ D V L I + ED G Y VV Sbjct: 3999 TKFVAHVSGVP--LPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVL 4056 Query: 1121 RNAAGEAQLSASMTV 1135 +N +G A SA ++V Sbjct: 4057 KNESGSATSSAKLSV 4071 Score = 51.6 bits (118), Expect = 2e-05 Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 3/97 (3%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 +P F+T+L+ P ++EG + + P P+ ++WY + + S HR RT D Sbjct: 3981 SPIFVTELS-PLSVTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFFDGHVV 4037 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 L I + ED G+Y N G A SS +L+V+ + Sbjct: 4038 KLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREE 4074 Score = 51.6 bits (118), Expect = 2e-05 Identities = 60/204 (29%), Positives = 83/204 (40%), Gaps = 31/204 (15%) Query: 1204 MGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHT 1263 +G+P V WF +G + SR L+I T D G Y A + LG+ Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236 Query: 1264 SAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETV 1323 S + V +A+ RR +V+ PQ S+ + N+ V Sbjct: 4237 SCTLDV-------------KAVRP--------RRGNEVQAC-----KPQTSK-MANVTAV 4269 Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD--YVALDLLSVYPEDSG 1381 EG V L+ R+ G VEWF + I G R++ A D +L + V EDSG Sbjct: 4270 EGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSG 4327 Query: 1382 VYTCQATNQLGEAVTSCALRVIAK 1405 Y A+N LGEA T L V K Sbjct: 4328 SYRAVASNNLGEATTLAELTVKGK 4351 Score = 51.6 bits (118), Expect = 2e-05 Identities = 54/191 (28%), Positives = 81/191 (42%), Gaps = 32/191 (16%) Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330 +P + ++ +G L +R + L+I P+DAG Y +A + LG C + Sbjct: 4179 NPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSC 4238 Query: 2331 SMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390 ++ V A RP + E+++ +P T + N+ + E Sbjct: 4239 TLDVKAV--------RPR---RGNEVQACKPQ----------------TSKMANVTAV-E 4270 Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI--TKTHDFGYVSMTISHVRDEDEGV 2448 G D R+ G P VEWFR E+ I D R + D G S+ IS V+ ED G Sbjct: 4271 GWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGS 4328 Query: 2449 YMCRASNLLGE 2459 Y ASN LGE Sbjct: 4329 YRAVASNNLGE 4339 Score = 51.6 bits (118), Expect = 2e-05 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 4/123 (3%) Query: 629 EEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688 EED + P F++ L T EG E +E G P K+EW KN + ++ S Sbjct: 4747 EED--WSAPSFVIELTPTTVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSY 4802 Query: 689 FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ 748 F I L + ++D+G Y C ++ G A + A L V T ++ + ++ Sbjct: 4803 FDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAVE 4862 Query: 749 QLE 751 E Sbjct: 4863 GTE 4865 Score = 51.2 bits (117), Expect = 2e-05 Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 2/97 (2%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 +AP T +K +V E + F + G PK + W ++G PI+A R+ D Sbjct: 183 KAPTVTSELKPDKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFDGTTS 240 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 L +K V +D GTY N+LG +++ L V K Sbjct: 241 TLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPK 277 Score = 51.2 bits (117), Expect = 2e-05 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+ IT ++D VE ++A F +P+ +EWF + G R+ + I Sbjct: 826 PEVITSMRDCD-CVEEETASFHCEFSGKPEPE--IEWFCGPNPIVPGGRFHVTEEGNIQS 882 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377 L I E++G Y+CVA+N G+ +T+A LK K Sbjct: 883 LAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 51.2 bits (117), Expect = 2e-05 Identities = 67/326 (20%), Positives = 117/326 (35%), Gaps = 15/326 (4%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGDVS 130 P FE G + +RG P P + W + L ++ Y + G Sbjct: 922 PEFEDWKDTIDALDGQDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHG--- 978 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190 L++ ++ P D G YTC A+N G V I E + T Sbjct: 979 LVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEALQKKGDTPTFMSKLEPIEITEGDDF 1038 Query: 191 YGTQGYTTEQSRQTQ----KVAYTNGTDHSSTDDFKVDTFEYRLLREVSF-RESITKRYV 245 + T + Q +V ++ D V ++E + + K V Sbjct: 1039 QLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL---TVKEAELDDDGVYKCVV 1095 Query: 246 GESDVQISTEIDRS-LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304 + +S++ D + L P++ QK + + EG A F V++ P+P + W+ Sbjct: 1096 TNNFGSVSSKADVTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGAT 1155 Query: 305 RLINSNKHEIITTHNHTT--LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362 ++ + + +I T + + L + + + D+G A N G V L VE + Sbjct: 1156 KITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKNVAP 1215 Query: 363 VQDQRSQYITDTQQRETEERIEISEK 388 R + + RE EIS K Sbjct: 1216 SFHGRQGRLRVKEGREASVYFEISGK 1241 Score = 51.2 bits (117), Expect = 2e-05 Identities = 36/149 (24%), Positives = 70/149 (46%), Gaps = 9/149 (6%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P F+++L P +++EG C + P P V+W+ + +++ R++ S D +A Sbjct: 1021 PTFMSKLE-PIEITEGDDFQLSCNVTGRPQPE--VQWFRDEVLIKPSRRFKASYDGNVSA 1077 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSR 1963 L + +D G Y C NN G S + V K +R + ++ ++ +E + Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH--LRPEVLQK-MDDVRTVE-GGK 1133 Query: 1964 YKRAVQDDSFVVEKPQFGKPIKNAEVTEG 1992 AV+ D+F KP+ + ++T+G Sbjct: 1134 ANFAVKIDAF--PKPEIEWYLGATKITDG 1160 Score = 51.2 bits (117), Expect = 2e-05 Identities = 57/254 (22%), Positives = 99/254 (38%), Gaps = 40/254 (15%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYV 1768 P MKD E A F+ ++ PK VEW I R LT + G Sbjct: 1704 PEILETMKDAEGIETGKAKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDEEDGTY 1761 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828 ++ + + ED GTY A N++G+ + L V+ K + + E ++ E Sbjct: 1762 SVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEKL---IAPEFEG-----RETEVPF 1813 Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888 R + + D+EV+ N +NG +P PD V WY + ++L Sbjct: 1814 RAKEKSDLEVSYN--------ING----------------KPSPD----VSWYRDDRLLL 1845 Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948 G ++ + V D+G Y C+A N +G A + + ++ ++ Sbjct: 1846 DGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVGSATRNFNVEIEVPKARDEAPSF 1905 Query: 1949 ESALEKIQYLEDDS 1962 + L+ I E ++ Sbjct: 1906 TTTLKPIDVTEGEN 1919 Score = 51.2 bits (117), Expect = 2e-05 Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY--DFGY 2034 KPQ K + N EG V L+ +T P VEW+ + G R+KT D G Sbjct: 4257 KPQTSK-MANVTAVEGWKVQLDTRMTGY--PVPIVEWFRGEEKITDGGRYKTARMEDEGL 4313 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 +L I ED+G+Y A+N +GEA T + + V K Sbjct: 4314 YSLIISDVQLEDSGSYRAVASNNLGEATTLAELTVKGK 4351 Score = 51.2 bits (117), Expect = 2e-05 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F+ L EG++ E VE + P K+EWF N+KP+ +S D + L + Sbjct: 4755 FVIELTPTTVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIV 4812 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 T ED+G+Y C N G+A++ L Sbjct: 4813 RRTTLEDAGLYRCTILNDLGTASSMADL 4840 Score = 51.2 bits (117), Expect = 2e-05 Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 2/108 (1%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F+ L A EG + F ++ G P +IEW ++G S+E+ R T+ + + +L Sbjct: 5249 PAFLKQLLPQNAREGDVVKFSCKV--TGYPEPEIEWTRDGVSMESDERVTTWYDGEHSTL 5306 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744 + + N DSG Y C + +G A + A L V + R S + + L Sbjct: 5307 SIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKTQRPRLSDNMKEL 5354 Score = 50.8 bits (116), Expect = 3e-05 Identities = 100/410 (24%), Positives = 163/410 (39%), Gaps = 75/410 (18%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P +K +V EG +T P + WY +G+P++ R K ++D Sbjct: 185 PTVTSELKPDKVQEGEQYKFTCAVTGKPKPV--ISWYKDGQPIKADRRVKDSFD------ 236 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD-TLDEQRLKKIQELEKYER 2096 T T + K VK D K ++ T D + +LE Sbjct: 237 -------GTTSTLLIK------------DVKQDDKGTYKVEITNDLGSISSTADLEV--T 275 Query: 2097 PKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156 PKP +P + + ++E++ EG A FE + + P +WFH+ +KI Sbjct: 276 PKPA-------KPEVVRKMENVESV-EGSDAFFEVKFKGYPIPKR--EWFHDSKKIEPSS 325 Query: 2157 RYR-TTHDFGYVA-LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214 R++ TT D + L I +DSG Y C A+N+ GE LKV +N + Sbjct: 326 RFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV---KNKPFAPEFA 382 Query: 2215 NG-LEKIRQLEAQGHSTRIEV---EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVH 2270 +G LE I E Q + R+ V +P+++ + T+L T + T P Sbjct: 383 DGDLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKA 442 Query: 2271 DPNLRIEFY-HNGKALQSAAR-FHIT---------FDFGYVSLDIQ---------HCVPE 2310 N +++ L S R F +T + G + L ++ + + Sbjct: 443 STNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLD 502 Query: 2311 DAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360 DAGEY VK N +G TS + V K + +PE L K+ ++ + E Sbjct: 503 DAGEYKVKVTNEVGSVTSLADINV-QKAKV-----KPEFLRKVEDVTALE 546 Score = 50.8 bits (116), Expect = 3e-05 Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 11/152 (7%) Query: 1280 QNEQAIEQIQLLEDAARRTKQVREDITVMQA-PQFSRALHNIETVEGTNVHLECRLQPVG 1338 Q+++ ++++ D + ++T A P+ R + N+E+VEG++ E + + G Sbjct: 249 QDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFK--G 306 Query: 1339 DQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL--SVYPEDSGVYTCQATNQLGEAVT 1396 + EWF + K I+ RF+ + L+ + +DSG Y C A+N+ GE Sbjct: 307 YPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGE--- 363 Query: 1397 SCALRVIAK-KDLILESQHPSG-LEKIQYLED 1426 C LR K K+ + G LE I+ ED Sbjct: 364 -CNLRADLKVKNKPFAPEFADGDLEPIEVKED 394 Score = 50.8 bits (116), Expect = 3e-05 Identities = 90/388 (23%), Positives = 157/388 (40%), Gaps = 30/388 (7%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFFNFG 965 KPE +++ S+ EG A FE + + G + EW D + +E SSR ITT Sbjct: 280 KPEVVRKMENVESV-EGSDAFFEVKFK--GYPIPKREWFHDSKKIEPSSRFKITTDDTEQ 336 Query: 966 YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLED 1025 +L I + + D+G Y C A N G+ A+L + K A G LE I+ ED Sbjct: 337 TSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKVKNKP--FAPEFADGDLEPIEVKED 394 Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQ 1085 + + T V KP GT ++ + + +A + G+ Sbjct: 395 QAVNVRLT---VTGNPKPEVTWYKDGT-QLHDTKKLKLKATGDVHELSIPKASTNDEGQY 450 Query: 1086 ITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSS 1145 A+ + G V GV V+ +G L + S++T+ Sbjct: 451 FCEAS-----NPLGSPKRTF-KVTVVPKGVAPVI---ESGLMPLQVRKETGAKWSVNTTL 501 Query: 1146 IHRGLYEKTRHIEESKFVEPMYQIE-EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPM 1204 G Y K + E V + I + +K KP F++ + + + E + + E ++ Sbjct: 502 DDAGEY-KVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQ-- 557 Query: 1205 GDPTMRVEWFHNGRSVTVGSRF--KTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAH 1262 G P VEW+ + G RF + +L I A + D+G Y A N G Sbjct: 558 GYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGK-- 615 Query: 1263 TSAIVRVIERSDIVTDTQNEQAIEQIQL 1290 T+A++ ++ ++ V + ++ ++ I++ Sbjct: 616 TTALLN-LDVNEKVVQPEFDKEVKPIEV 642 Score = 50.8 bits (116), Expect = 3e-05 Identities = 52/244 (21%), Positives = 94/244 (38%), Gaps = 27/244 (11%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576 P E+ E Q + R+ G+P WY +G +L + + L I N Sbjct: 388 PIEVKEDQAVN--VRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTN 445 Query: 2577 DAGLYMCKAINRAGXXXXXXXXXXX--XXXXIIDQAMRP--------ESWE-QIQLKEAA 2625 D G Y C+A N G +I+ + P W L +A Sbjct: 446 DEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAG 505 Query: 2626 MNKVP--------EMFVDTGVQQAPIFTTHLKSYDKL--VEGQHVYLEAQVEPRTDPNLK 2675 KV D VQ+A + L+ + + +E + V+ E ++ P Sbjct: 506 EYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPI-- 563 Query: 2676 IEWFKNGVTLTTGAR--LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733 +EW++ + G R + + + + +L I+ R +DSG Y C A+N G+ + ++ Sbjct: 564 VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLD 623 Query: 2734 IEDR 2737 + ++ Sbjct: 624 VNEK 627 Score = 50.8 bits (116), Expect = 3e-05 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F+ L P ++EG + L C + G P V+WF + + RFK YD A Sbjct: 1021 PTFMSKLE-PIEITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 1077 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 L + A D G Y N+ GS + A V V+++ Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113 Score = 50.8 bits (116), Expect = 3e-05 Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 3/100 (3%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 +++AP+F + L+ + EG +V +V P +EW+++ L R K FD Sbjct: 2188 LKEAPVFVSKLRPLF-VTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDG 2244 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 + +L ++ D G+Y C TN G A S+A ++++ + Sbjct: 2245 RVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKK 2284 Score = 50.8 bits (116), Expect = 3e-05 Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 2/77 (2%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P +I+W KNG + + RL++ +D + LSI + +DD+G Y C A+N G S+A+ Sbjct: 2962 PKPQIKWTKNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAA 3021 Query: 2732 IKIEDRHW--LLGESLH 2746 + + R+ L+ LH Sbjct: 3022 LTVSRRNMRPLITHKLH 3038 Score = 50.8 bits (116), Expect = 3e-05 Identities = 89/382 (23%), Positives = 140/382 (36%), Gaps = 61/382 (15%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK--TTYDFGY 2034 +P + + + EG + +T PT VEW+ + +G R++ + + G Sbjct: 3030 RPLITHKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEEQGK 3087 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094 +L + A+D G Y C A N G+A T + + V A+ + DE+ Sbjct: 3088 HSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIARD--FGPEFDEE----------- 3134 Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154 E PKP+ + EG+ A V P ++WF +G+ + Sbjct: 3135 ESPKPV-------------------IVNEGEEAQMMVSVR--GRPKAVVEWFKDGKFLYD 3173 Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214 R L I + ED G+Y C A++ G + T L V + P Sbjct: 3174 SRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRTFDLSVKVPKPKD-KWSLP 3232 Query: 2215 NGLEKIRQLEA-QGHSTRIEVE---EP-------KISPP-----RFVTELRGTTHVFE-G 2257 K+R LE +G T+ V EP K P RF T G + Sbjct: 3233 AFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFR 3292 Query: 2258 KTAHFEC-----QVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDA 2312 KT FEC + P +E++ L R+ + +L I + ED Sbjct: 3293 KTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDT 3352 Query: 2313 GEYSVKAINALGHCTSAISMTV 2334 G Y + A N G S + +TV Sbjct: 3353 GPYKIIATNEHGSTGSVVDLTV 3374 Score = 50.8 bits (116), Expect = 3e-05 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP F + + V E ++ E + G P +VEW +N P++ + + + D + Sbjct: 4752 APSFVIELTPTTVTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIR 4809 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 L ++ ED+G Y C +N+LG A + + L V Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842 Score = 50.8 bits (116), Expect = 3e-05 Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 4/98 (4%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS-IFNFGY 827 +P+ L+ + E EG A F+ +T P RV+WY+ IT +R +S + + G Sbjct: 5639 KPEINEKLKKI-EAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGM 5695 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 SL I +R ED G Y AVN+ GE S + V + Sbjct: 5696 ASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733 Score = 50.4 bits (115), Expect = 3e-05 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 3/99 (3%) Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162 ++ G P F++ L +E + EGD C V P + WF + I+ R++ ++ Sbjct: 1015 QKKGDTPTFMSKLEPIE-ITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFKASY 1071 Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 D AL + +D G Y C TN G + + V Sbjct: 1072 DGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV 1110 Score = 50.4 bits (115), Expect = 3e-05 Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFG 2432 RP+ T L ++ EG+ A FD + G P+ VEWF+ I + R + + G Sbjct: 3030 RPLITHKLHDM-KAYEGKEARFDIEV--TGHPSPTVEWFKGPSGISEGRRYQLMSNEEQG 3086 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459 S+ +S + +D+G+Y C A NL G+ Sbjct: 3087 KHSLIVSDLNADDDGIYKCVAQNLAGK 3113 Score = 50.4 bits (115), Expect = 3e-05 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P F P++ I I EG F + G VEW +D RPV R+ T+ + V Sbjct: 5544 PAFTAPLQ-HIDILEGDTTRFIGEIT--GVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 L ++ + DAG + C N +G +SA+L + Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633 Score = 50.0 bits (114), Expect = 5e-05 Identities = 21/68 (30%), Positives = 39/68 (57%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P +IEWF + G R T + + +L+I+ L+ +D+G Y C A+N G+ + A Sbjct: 853 PEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAE 912 Query: 2732 IKIEDRHW 2739 +K+ ++H+ Sbjct: 913 LKVNEKHF 920 Score = 50.0 bits (114), Expect = 5e-05 Identities = 60/229 (26%), Positives = 90/229 (39%), Gaps = 39/229 (17%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 KPE +KD + EG A F +L G + +EW + R + Sbjct: 1410 KPEVLEKMKDVKGV-EGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGRYKFSRDDQKY 1466 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027 +LTIK + + D G Y C A N G+ T A L + E + E+ Q+LE Sbjct: 1467 SLTIKDLNLQDIGTYKCIASNEAGKVTQRAELE-------VKERDYAPIFEEKQFLEPL- 1518 Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT 1087 E+++ Q P++ S H R +P TV W+ NGK++ Sbjct: 1519 --------EIQVRQ------PVE--------VSYHVRGRPKP------TVTWWKNGKELR 1550 Query: 1088 SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 ++ Y L I ED+G Y +ARN G A+ + VE Sbjct: 1551 DGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVE 1599 Score = 50.0 bits (114), Expect = 5e-05 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 3/93 (3%) Query: 929 FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988 FE + G EWLKD +PV+ +++ F+ L K V + D G YT N Sbjct: 1625 FELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKN 1684 Query: 989 AIGQATTSANLTIV---TKKDIIAESQHPGGLE 1018 A G +SANL IV +K +I+ + G+E Sbjct: 1685 AHGSTYSSANLDIVKSKSKPEILETMKDAEGIE 1717 Score = 50.0 bits (114), Expect = 5e-05 Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 14/162 (8%) Query: 2100 IEEEQPGQR---PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156 +E E P R P F T L ++ + EG+ F CRV +P +T W+ N +I Sbjct: 1891 VEIEVPKARDEAPSFTTTLKPID-VTEGENHTFICRVHARPEPSVT--WYRNKNEIVPDG 1947 Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNG 2216 R RTT D L + +D+G Y C A+N +G+A CT ++ ++ + P Sbjct: 1948 RSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAF--CTAEMTVNKREV----KPVI 2001 Query: 2217 LEKIRQLE-AQGHSTRIEVEEPKISPPRFVTELRGTTHVFEG 2257 E + E ++G + IEV+ + P V G+ V +G Sbjct: 2002 KEVSKTFEVSEGGTASIEVKVSGVPVPT-VEWYHGSNRVLDG 2042 Score = 50.0 bits (114), Expect = 5e-05 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Query: 2366 EIPEPVTR-QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR 2424 EI P R + P FT L+ ID + EG+ F CR+ +P+ V W+RN+ I R Sbjct: 1892 EIEVPKARDEAPSFTTTLKPID-VTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGR 1948 Query: 2425 ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 T D + + ++ +D G Y C ASN +G+ Sbjct: 1949 SRTTFDGETYKLILQDIKIKDAGQYECIASNPIGK 1983 Score = 50.0 bits (114), Expect = 5e-05 Identities = 45/155 (29%), Positives = 71/155 (45%), Gaps = 13/155 (8%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 G+ P F L + ++E D + C V P I W NG+ + + R RT +D G Sbjct: 2932 GEAPSFSLELRPIAAIEEFD-SKLICHVS--GKPKPQIKWTKNGKPVESDGRLRTDYD-G 2987 Query: 2166 YVA-LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224 VA L I +D+GTY C A+N G ++ L V+ RN+ P K+ ++ Sbjct: 2988 IVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVS-RRNM-----RPLITHKLHDMK 3041 Query: 2225 A-QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258 A +G R ++E P V +G + + EG+ Sbjct: 3042 AYEGKEARFDIEVTG-HPSPTVEWFKGPSGISEGR 3075 Score = 50.0 bits (114), Expect = 5e-05 Identities = 31/128 (24%), Positives = 60/128 (46%), Gaps = 8/128 (6%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 PKF++ + S V+E + + C++ K +P +EW+++ +L+ + R R+ +L Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTL 3744 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949 V +D G Y C A N G + A I + + PR +++ + ++ T Sbjct: 3745 IFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNR------ASITPRIIEKPRDVDAVDGT 3798 Query: 3950 IKKYTSEV 3957 K+T V Sbjct: 3799 DAKFTVRV 3806 Score = 50.0 bits (114), Expect = 5e-05 Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 4/135 (2%) Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749 EK + P F E+ + V EG F V G P I W+ + P ++ R+ T D Sbjct: 3977 EKWSSPIFVTELSP-LSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFD 4033 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809 + L I I D G+Y N+ GSAT++AK++ + +QL + + G Sbjct: 4034 GHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVEGFDGS 4093 Query: 3810 ELE-RGRISDAPKEE 3823 E E ++S P E Sbjct: 4094 ESELTVQVSGVPAAE 4108 Score = 50.0 bits (114), Expect = 5e-05 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 4/89 (4%) Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT--LNDFGFIALDIDYIY 3761 N+ EG V D R+ G P ++WF G R T + D G +L I + Sbjct: 4265 NVTAVEGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQ 4322 Query: 3762 ARDAGEYTCRATNKWGSATTTAKITCSAK 3790 D+G Y A+N G ATT A++T K Sbjct: 4323 LEDSGSYRAVASNNLGEATTLAELTVKGK 4351 Score = 50.0 bits (114), Expect = 5e-05 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 3/101 (2%) Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 + E+ P F+ L + EG + E ++T P +VEW+K+ +P+ + S Sbjct: 4745 VPEEDWSAPSFVIELTPT-TVTEGESTALEVEIT--GTPLPKVEWFKNDKPVKHDHLVRS 4801 Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 F+ + L + EDAG Y +N LG A S A + V Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842 Score = 50.0 bits (114), Expect = 5e-05 Identities = 21/69 (30%), Positives = 40/69 (57%) Query: 933 LEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ 992 +E G +VEW K+ +PV+ + ++F+ + L ++ T+ DAG Y C N +G Sbjct: 4774 VEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGT 4833 Query: 993 ATTSANLTI 1001 A++ A+L++ Sbjct: 4834 ASSMADLSV 4842 Score = 50.0 bits (114), Expect = 5e-05 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 3/93 (3%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P F PL+ + I+EG + F + VEWY + + +T +R++TY D V Sbjct: 5544 PAFTAPLQHID-ILEGDTTRFIGEITGVP--VPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 L + D+GV+ V RN G SAS+ V Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633 Score = 49.6 bits (113), Expect = 6e-05 Identities = 92/392 (23%), Positives = 154/392 (39%), Gaps = 53/392 (13%) Query: 3295 VEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIVILDILYCYEENSG 3353 VE A F+ + P VEW+ K+ +++ D G L I ++++G Sbjct: 3 VESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAG 60 Query: 3354 EYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVE 3413 Y+CVATN G+ S + +L K+ P+ E E ++ E V T Sbjct: 61 AYKCVATNDAGQTSLRGDLSVKEKQIA------PQIKEKEQEPIEVFEGESVNLDLTITG 114 Query: 3414 EEKGKAPVFT--VPLSNIEN--LREGENAHFEA--RLTPTDDPNLKVEWYWNGKSLKAGS 3467 + K + + PL ++ L+ ++++F + + TP D K E K+ K G+ Sbjct: 115 KPKPEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCE----AKN-KIGT 169 Query: 3468 RFRTFCDFGFVILEISPTYPED-------SGE---YLCRAYNNYGEAVT--------TAS 3509 R F D + +PT + GE + C ++ A Sbjct: 170 SARDF-DVNVKVKGKAPTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQPIKAD 228 Query: 3510 MKVQ----GKRNIILESQLPKGMEGT--IDKIAALEGYSGTVDT-LTPEAESGNPPEFTT 3562 +V+ G + +L + + +GT ++ L S T D +TP+ PE Sbjct: 229 RRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAK---PEVVR 285 Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI--LEIG 3620 ++ E S A FE + + EWFH+ K + SR K D L I Sbjct: 286 KMENVESVEGSDAFFEVKF--KGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVIS 343 Query: 3621 GVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 + D+G Y C A+N GE + L+VK + Sbjct: 344 DLRLDDSGAYQCIASNEAGECNLRADLKVKNK 375 Score = 49.6 bits (113), Expect = 6e-05 Identities = 33/109 (30%), Positives = 50/109 (45%), Gaps = 4/109 (3%) Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288 + ++VE+ + P +T +R V E +TA F C+ +P IE++ + Sbjct: 814 AAEVKVEDRSLKP-EVITSMRDCDCV-EEETASFHCEFSGKPEPE--IEWFCGPNPIVPG 869 Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 RFH+T + SL I EDAG Y A NA G T+ + V K Sbjct: 870 GRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 49.6 bits (113), Expect = 6e-05 Identities = 39/156 (25%), Positives = 66/156 (42%), Gaps = 10/156 (6%) Query: 3365 RDSTKANLKCTSK-ENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEE----KGKA 3419 R++ +KC L+L P + G+ + ++ + KD ++ E KG Sbjct: 963 RNTMHVQIKCYGDLHGLVLYKVSPE--DAGMYTCRAKNNAGIVSKDVTITVEALQKKGDT 1020 Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 P F L IE + EG++ F+ T P +V+W+ + +K RF+ D Sbjct: 1021 PTFMSKLEPIE-ITEGDD--FQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 1077 Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 L + +D G Y C NN+G + A + V K Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113 Score = 49.6 bits (113), Expect = 6e-05 Identities = 64/276 (23%), Positives = 107/276 (38%), Gaps = 42/276 (15%) Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740 +R E+ +++ P + + +++ PV V G P + W+ NG+ Sbjct: 1494 QRAELEVKERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVR--GRPKPTVTWWKNGKELRD 1551 Query: 3741 GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800 G V + + L I DAG Y C A N GS A+R + E Q+ Sbjct: 1552 GKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGS----------AER--LFEVQV- 1598 Query: 3801 QGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPK 3860 E +K PKEE PK +Q++S + ES+ C V+ DP Sbjct: 1599 -----EGVK----------PKEEA-----PKLTSQLRSARITESDDFELACDVKGTPDPS 1638 Query: 3861 LRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKAT-- 3918 EW ++ K + + +D +L+ V D G Y N G ++ A Sbjct: 1639 Y--EWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLD 1696 Query: 3919 -ISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKY 3953 + K P+I+ + G++ +A + + IK Y Sbjct: 1697 IVKSKSKPEILETMKDAEGIETGKA--KFDVKIKAY 1730 Score = 49.6 bits (113), Expect = 6e-05 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 2/73 (2%) Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL-NMKYVNPEDSGTYTCRAINELGEAV 1795 +G+P+ V W ++G+ + ++R T M G + N+ +V PED+GTY C A N LG + Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSR-TDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSF 2711 Query: 1796 TSSTLFVQSKASL 1808 S T+ ++ S+ Sbjct: 2712 RSCTIEIKEPKSV 2724 Score = 49.6 bits (113), Expect = 6e-05 Identities = 25/68 (36%), Positives = 40/68 (58%), Gaps = 2/68 (2%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVA-LDILYAYAEDTGTYMCKATNAVGEAVTTS 2065 P +++W NG+PV+ R +T YD G VA L I +D GTY C A+NA G +++ Sbjct: 2962 PKPQIKWTKNGKPVESDGRLRTDYD-GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSA 3020 Query: 2066 SVKVDAKS 2073 ++ V ++ Sbjct: 3021 ALTVSRRN 3028 Score = 49.6 bits (113), Expect = 6e-05 Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 7/121 (5%) Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAVNQA----PRFITQLNGPTKLSEGQSAHYECRIEP 1870 +S L K + + + DV+ V P+F++ LN + EG SA C++ Sbjct: 3654 DSGLYKCEGVSTLGTSSKTFDVKAGVPDGSRVTPKFLSHLNS-LDVDEGDSAKLTCKMFG 3712 Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930 P+P VEW+ + +++ + R R+S L TV +D G Y C A N G S Sbjct: 3713 KPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSS 3770 Query: 1931 S 1931 S Sbjct: 3771 S 3771 Score = 49.6 bits (113), Expect = 6e-05 Identities = 53/206 (25%), Positives = 85/206 (41%), Gaps = 30/206 (14%) Query: 2000 TLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059 T + +P V W+ +G + + R L+I +D GTY+C+A + +G Sbjct: 4173 TFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLG 4232 Query: 2060 EAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLE 2119 + ++ V A + +R ++Q KP + +TA+ Sbjct: 4233 TCFRSCTLDVKA--------VRPRRGNEVQAC------KPQTSKMAN-----VTAV---- 4269 Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH--DFGYVALDILYTYAE 2177 EG + + R+ P ++WF +KI G RY+T D G +L I E Sbjct: 4270 ---EGWKVQLDTRMTGYPVP--IVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLE 4324 Query: 2178 DSGTYMCKATNKLGEAVNTCTLKVAG 2203 DSG+Y A+N LGEA L V G Sbjct: 4325 DSGSYRAVASNNLGEATTLAELTVKG 4350 Score = 49.6 bits (113), Expect = 6e-05 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 10/133 (7%) Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162 E+ P F+ LT + EG+ E VE P ++WF N + ++ H R+ Sbjct: 4747 EEDWSAPSFVIELTPT-TVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSYF 4803 Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQ 2222 D + L + T ED+G Y C N LG A + L V +R + P EK+ Sbjct: 4804 DGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV--NRAL----TKPEVAEKMTD 4857 Query: 2223 LEA-QGHSTRIEV 2234 ++A +G R+EV Sbjct: 4858 IDAVEGTEVRLEV 4870 Score = 49.6 bits (113), Expect = 6e-05 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGE 1916 EG A ++ + +P P RV+WY + +RY T G A+L I + ED G Sbjct: 5653 EGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGL 5710 Query: 1917 YTCKAINNLGQAVSSIRLNVQSK 1939 Y C A+N G+ S + L+V K Sbjct: 5711 YGCVAVNEYGETTSIVDLHVGEK 5733 Score = 49.2 bits (112), Expect = 8e-05 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 3/96 (3%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 G+ P + L + ++EG++ F C V P I W+ +GQ I+A R + + D Sbjct: 182 GKAPTVTSELKP-DKVQEGEQYKFTCAVT--GKPKPVISWYKDGQPIKADRRVKDSFDGT 238 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 L I +D GTY + TN LG +T L+V Sbjct: 239 TSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEV 274 Score = 49.2 bits (112), Expect = 8e-05 Identities = 79/341 (23%), Positives = 124/341 (36%), Gaps = 57/341 (16%) Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330 +P + +Y +G L + + L I D G+Y +A N LG Sbjct: 406 NPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTF 465 Query: 2331 SMTVTAKG--SIISESQRPEGLEKIR--------ELESAEPFKRPEIPE--PVTRQRPVF 2378 +TV KG +I P + K L+ A +K E VT + Sbjct: 466 KVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVTSLADIN 525 Query: 2379 TQP-------LQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT--KTH 2429 Q L+ ++++ +T + G P VEW+R I+D R T ++ Sbjct: 526 VQKAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESE 585 Query: 2430 DFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQK 2489 + S+ I R ED G Y C ASN G+ + L+ +K Sbjct: 586 ENDMYSLVIDEARTEDSGPYKCVASNDAGK----------TTALLNLDVN--------EK 627 Query: 2490 LEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGV 2549 + QP EF+K + P E+ G+ A + G P + WY + V Sbjct: 628 VVQP----------EFDKEV------KPIEVKHGEEATTSLEI--KGKPKPKVTWYKDLV 669 Query: 2550 ELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 L + TL+I + +D G Y C+A N+AG Sbjct: 670 PLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAG 710 Score = 49.2 bits (112), Expect = 8e-05 Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 3/98 (3%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 +AP F +L P E + C + P P +++W NGK ++S R RT D Sbjct: 2933 EAPSFSLELR-PIAAIEEFDSKLICHVSGKPKP--QIKWTKNGKPVESDGRLRTDYDGIV 2989 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 A L I V +D+G Y C A N G SS L V + Sbjct: 2990 AYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027 Score = 49.2 bits (112), Expect = 8e-05 Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 3/124 (2%) Query: 3531 TIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMR 3590 T D +A ++ V + P+ E + P F T S L ++E F + V S Sbjct: 3956 TNDLGSAYRIFNLNVTAIAPK-EKWSSPIFVTELSPLSVTEGDYTKFVAHVSGVPLPS-- 4012 Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 ++W+ + P+ + R++T D V L IG + D G Y N G AT S KL V+ Sbjct: 4013 IQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVR 4072 Query: 3651 GRQG 3654 G Sbjct: 4073 EEYG 4076 Score = 49.2 bits (112), Expect = 8e-05 Identities = 37/151 (24%), Positives = 70/151 (46%), Gaps = 8/151 (5%) Query: 3366 DSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRK--DTSVEE--EKGKAPV 3421 DS + NL+ + ++ + G+ K +T + + D +E+ + AP Sbjct: 4398 DSRRVNLRSVGERYYVVVPSASFE-DSGIYKCETTSEKETTSQLFDIHIEDVCKSALAPG 4456 Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481 F L +++ + E E+A F ++ + P +++W+ N + + SR T D L Sbjct: 4457 FKSALRSLD-VTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPVHKLA 4513 Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 I+ +D+G Y C A N+ G A +TA + V Sbjct: 4514 ITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 49.2 bits (112), Expect = 8e-05 Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 27/187 (14%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXX 2463 G+P +V W+++ L+ D++R+ + I + ED G YMC A + LG+ Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031 Query: 2464 XXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523 L+ Q + K E H + KP+ T+ + ++ EG Sbjct: 5032 CI----------LDVQ------AVPKEEVDH--------GQIVKPVITRKIR-DAQGEEG 5066 Query: 2524 QHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583 + +E V P EWY ++L G +++ + G +L I V +D G Y Sbjct: 5067 SNIRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKV 5124 Query: 2584 KAINRAG 2590 A N+AG Sbjct: 5125 VATNQAG 5131 Score = 49.2 bits (112), Expect = 8e-05 Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 2/74 (2%) Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845 +EG NI FE +V+ P +EW+ + L G +Y+ + SL IT ++D+G Sbjct: 5064 EEGSNIRFEIHVKSHPPP--HVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGS 5121 Query: 2846 YTCKATNSKGSATT 2859 Y ATN GS+T+ Sbjct: 5122 YKVVATNQAGSSTS 5135 Score = 49.2 bits (112), Expect = 8e-05 Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 3/81 (3%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 P +++W++ +T R ST G+ +L+I +R +D G+Y C A N GE S Sbjct: 5667 PPPRVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIV 5726 Query: 2731 SIKIEDRHWLLGESLHPDSLD 2751 + + ++H+ G + LD Sbjct: 5727 DLHVGEKHY--GPEFAEEELD 5745 Score = 48.8 bits (111), Expect = 1e-04 Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 4/99 (4%) Query: 4106 KARCPPVFVSL-PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM 4164 K + P V L PD V +EGE +F C VTG PKP + W +G I R K ++DG Sbjct: 181 KGKAPTVTSELKPDKV--QEGEQYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDGT 238 Query: 4165 YH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202 I +Q D G +V L+V P+ Sbjct: 239 TSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPK 277 Score = 48.8 bits (111), Expect = 1e-04 Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 9/159 (5%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P +++K V+E E +F C V K PK I WY++G+ + + R + +D +L Sbjct: 185 PTVTSELKPDKVQEGEQYKFTCAVTGK--PKPVISWYKDGQPIKADRRVKDSFDGTTSTL 242 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949 I V +D G Y ND G + A + P + +V R M+ E++ +A Sbjct: 243 LIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKP---AKPEVVRKMENVESVEGSDAF 299 Query: 3950 IK-KYTSEVYLTEDDLYDVDKKQPP---RFVTQIQSQTS 3984 + K+ + +D K +P + T QTS Sbjct: 300 FEVKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTS 338 Score = 48.8 bits (111), Expect = 1e-04 Identities = 59/226 (26%), Positives = 89/226 (39%), Gaps = 38/226 (16%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+ + +K V +EG + F ++ G P+ IEW I R+ SL Sbjct: 1411 PEVLEKMKDVKGVEGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGRYKFSRDDQKYSL 1468 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756 + LN+QD G Y C A + G VT RA +E + DY+ Sbjct: 1469 TIKDLNLQDIGTYKCIASNEAG--------KVTQRAELEVKER------------DYAPI 1508 Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816 EE+ QF+ PL E+Q + + PT V W+K+G+ + Sbjct: 1509 -----FEEK-----QFLEPL----EIQVRQPVEVSYHVRGRPKPT--VTWWKNGKELRDG 1552 Query: 817 SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 + Y +L I+ EDAGSY A N +G A ++V Sbjct: 1553 KHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQV 1598 Score = 48.8 bits (111), Expect = 1e-04 Identities = 23/69 (33%), Positives = 37/69 (53%) Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397 G T + W+ +G+P+ R + L +L++ PED+G YTC+A N++G A S Sbjct: 2861 GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920 Query: 1398 CALRVIAKK 1406 + V A K Sbjct: 2921 FEVDVTAPK 2929 Score = 48.8 bits (111), Expect = 1e-04 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Query: 2646 THLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFGLVTLS 2703 TH K EG+ + +V P +EWFK ++ G R L S + G +L Sbjct: 3034 THKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEEQGKHSLI 3091 Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 ++ L DD GIY C A NL G+A + A + + Sbjct: 3092 VSDLNADDDGIYKCVAQNLAGKASTRAMLDV 3122 Score = 48.8 bits (111), Expect = 1e-04 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 3/94 (3%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP F L + EG+ LE ++ P K+EWFKN + ++S FD ++ Sbjct: 4752 APSFVIELTP-TTVTEGESTALEVEITGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVI 4808 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L + +D+G+Y C N LG A S A + + Sbjct: 4809 RLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842 Score = 48.4 bits (110), Expect = 1e-04 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 1835 DVEVA--VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892 DVEV V AP QL ++EG C++ YP+P + EW N ++L R Sbjct: 1304 DVEVKQEVMIAPEIRQQLQAED-VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDR 1360 Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 ++T D L I V D+ Y N+ G+ SS +L V K Sbjct: 1361 FKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK 1407 Score = 48.4 bits (110), Expect = 1e-04 Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248 V+EG + L C++ +PT+ EW N ++ RFKT +D L I + T AD Sbjct: 1326 VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAV 1383 Query: 1249 EYTVRAVNHLGSAHTSAIVRVIER 1272 Y V N G +SA ++VI + Sbjct: 1384 PYKVVVRNDAGEVSSSAKLKVIRK 1407 Score = 48.4 bits (110), Expect = 1e-04 Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EGD F NV+ S P+ IEW++ + G RYK + D SL I +D G Y Sbjct: 1424 EGDEATF--NVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTY 1481 Query: 2847 TCKATNSKGSATTSGSL 2863 C A+N G T L Sbjct: 1482 KCIASNEAGKVTQRAEL 1498 Score = 48.4 bits (110), Expect = 1e-04 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 7/159 (4%) Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVD 3142 EW + K ++ + + + L + +D G+Y+ N G S L+ V Sbjct: 1640 EWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIV- 1698 Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202 KSK KP +++ EG++ G+ A F+ + P ++EWYH + R Sbjct: 1699 KSK-SKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQ 1754 Query: 3203 D--FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239 D G + I + D G Y A+N G+ RA + Sbjct: 1755 DEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAEL 1793 Score = 48.4 bits (110), Expect = 1e-04 Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 5/108 (4%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 ++T K P F++E++ + E C V G P +I W NG+P + R Sbjct: 2924 DVTAPKVKGEAPSFSLELRPIAAIEEFDS-KLICHVS--GKPKPQIKWTKNGKPVESDGR 2980 Query: 3744 VHTLNDFGFIA-LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 + T D G +A L I + DAG Y C A+N G+ +++A +T S + Sbjct: 2981 LRTDYD-GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027 Score = 48.4 bits (110), Expect = 1e-04 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 2/123 (1%) Query: 625 IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684 + G D P+F+ L S+ EG ++ G P +EW K+ Q I + R Sbjct: 3675 VKAGVPDGSRVTPKFLSHLNSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDR 3732 Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744 S +L ++NIQD G Y C A + G + AV+ V + R + P + Sbjct: 3733 VRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNRASITPRIIEKPRDV 3792 Query: 745 QYI 747 + Sbjct: 3793 DAV 3795 Score = 48.4 bits (110), Expect = 1e-04 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 3/80 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P F L+++D + E ++A F C + G P +++WF N++ + SRI + D Sbjct: 4455 PGFKSALRSLD-VTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511 Query: 2436 MTISHVRDEDEGVYMCRASN 2455 + I+ +D GVY C A N Sbjct: 4512 LAITKATLQDTGVYKCLAVN 4531 Score = 48.4 bits (110), Expect = 1e-04 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 3/83 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P FT PLQ+ID I EG T F + G P VEW+R+++ + R+ D V Sbjct: 5544 PAFTAPLQHID-ILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 + + D GV+ C N LG Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLG 5623 Score = 48.0 bits (109), Expect = 2e-04 Identities = 87/368 (23%), Positives = 140/368 (38%), Gaps = 46/368 (12%) Query: 3591 VEWFHNGKPLLTGSRVKTI-NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 VEW+ + + + K + +D G L I + + DAG Y C ATN G+ ++ L V Sbjct: 22 VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRGDLSV 81 Query: 3650 KGRQGIILEPQLPSHFKSGTESIQ----KLEETLH---KREEITIEDEKPNPPRFTVEIK 3702 K +Q + PQ+ + E + L+ T+ K E + +D KP ++++K Sbjct: 82 KEKQ---IAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSIDLK 138 Query: 3703 DNID-----VPEGGPVH---FDCRVE-PVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753 D +P+ P + C + +G + R F +V Sbjct: 139 STDDSYFLSIPKATPNDSGKYKCEAKNKIGT---------SARDFDVNVKVKGKAPTVTS 189 Query: 3754 ALDIDYIYARDAGEYTCRATNK------WGS------ATTTAKITCSAKRDIVLESQLPQ 3801 L D + + ++TC T K W A K + +L + Q Sbjct: 190 ELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQ 249 Query: 3802 GMSGEKIKEL--ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859 G E+ + G IS E + P K K VE EG V+ K P Sbjct: 250 DDKGTYKVEITNDLGSISSTADLE-VTPKPAKPEVVRKMENVESVEGSDAFFEVKFKGYP 308 Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYD--MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKA 3917 + EW+ + K + R++ D SL I + +DSG Y C A N+ GE +A Sbjct: 309 IPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGECNLRA 368 Query: 3918 TISCKKLP 3925 + K P Sbjct: 369 DLKVKNKP 376 Score = 48.0 bits (109), Expect = 2e-04 Identities = 39/151 (25%), Positives = 61/151 (40%), Gaps = 13/151 (8%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F ++ I + E F+ G P+ V+W R+ V I+ S R +D AL Sbjct: 1021 PTFMSKLEPIEITEGD--DFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 1078 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH--ESALQKIQQLEDSS 1828 +K +D G Y C N G V SKA + + +H LQK+ + Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFGS--------VSSKADVTVLKKHLRPEVLQKMDDVRTVE 1130 Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859 + V++ P L G TK+++G Sbjct: 1131 GGKANFAVKIDAFPKPEIEWYL-GATKITDG 1160 Score = 48.0 bits (109), Expect = 2e-04 Identities = 75/331 (22%), Positives = 121/331 (36%), Gaps = 52/331 (15%) Query: 2272 PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS 2331 P+ +E+Y L S + + G L+I+ +DAG Y KA N++G + I Sbjct: 2123 PSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRII 2182 Query: 2332 MTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEG 2391 + V A L+ A F V++ RP+F N+ Sbjct: 2183 VDVEA-------------------LKEAPVF--------VSKLRPLFVTEGDNVS----- 2210 Query: 2392 QTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMC 2451 + C++ + PT VEW+R+ + + +R D S+ +S +D+GVY C Sbjct: 2211 ----WMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNC 2264 Query: 2452 RASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE-RRSEEPDREF----- 2505 +N G + ++ ++ E + R S P E Sbjct: 2265 VITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRN 2324 Query: 2506 ------EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT 2559 EK L P + E +++ RV G P WY +G ++ RF Sbjct: 2325 SIKVRNEKFYGDDELKEPVVVQESDAINFKVRV--RGKPVPTIVWYKDGEMVRDVRRFEI 2382 Query: 2560 THDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 T S A DAG Y C+A N+ G Sbjct: 2383 RSRGDIYTFATYSASAEDAGTYTCEASNKLG 2413 Score = 48.0 bits (109), Expect = 2e-04 Identities = 55/232 (23%), Positives = 92/232 (39%), Gaps = 39/232 (16%) Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERR--LIPVSDATLKVEWYHNNKPLKSGSRFT 1627 VD T+AP +K+ EG R L+ SD + +EW+ L+ G ++ Sbjct: 2724 VDSTDTRAPGQLIPVKHKFDFEGVPGGKARCDVLVKKSDI-IDIEWFRGTNMLRDGDKYK 2782 Query: 1628 --ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685 ++++ ++L + + ED+GTY C +VH+ G Sbjct: 2783 ILKSDDGQTLSLIVENVCGEDAGTYRC---------------VVHTPA---------GQT 2818 Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745 +L K Q DE ++Q F++P Q G P + Sbjct: 2819 TIRGELHIKEKQQAPLFLDEKVSQEK-FSLP---------QGQEMNKSFTVTGSPTPHIT 2868 Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 W ++G P++ + R+ L + + PED+GTYTC A N +G A S Sbjct: 2869 WYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920 Score = 48.0 bits (109), Expect = 2e-04 Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 5/133 (3%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P FL+ L SL+ + EGD A C++ P T++WF + Q I R R++ Sbjct: 3687 PKFLSHLNSLD-VDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCT 3743 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGH 2228 L +D G Y C ATN+ G ++ + V + P ++ + +A+ Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNRASITPRIIEKPRDVDAVDGTDAK-F 3802 Query: 2229 STRIE-VEEPKIS 2240 + R+E +PK++ Sbjct: 3803 TVRVEGFPQPKVT 3815 Score = 48.0 bits (109), Expect = 2e-04 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 2/89 (2%) Query: 67 GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126 G+ P+ + ++A+ +G N +FE ++ +P P V W R L KY + +E Sbjct: 5047 GQIVKPVITRKIRDAQGEEGSNIRFEIHVKSHPPPHVEWYRGSIKLAHGPKYQI--SEGD 5104 Query: 127 GDVSLLIKQIGPGDEGEYTCTARNQYGEA 155 G SL I + D G Y A NQ G + Sbjct: 5105 GAYSLTITGVQKDDTGSYKVVATNQAGSS 5133 Score = 48.0 bits (109), Expect = 2e-04 Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 2/88 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F+ L +EGD + F C V +P +IEW + + S R + +D + +L I Sbjct: 5251 FLKQLLPQNAREGDVVKFSCKVTGYPEP--EIEWTRDGVSMESDERVTTWYDGEHSTLSI 5308 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 + DSG+Y C N+ G A++S L Sbjct: 5309 HNANHADSGMYKCTLKNNSGWASSSAEL 5336 Score = 47.6 bits (108), Expect = 2e-04 Identities = 47/210 (22%), Positives = 84/210 (40%), Gaps = 23/210 (10%) Query: 3996 QLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV-AMNFGWVYPEDSGEYLCRATNLY 4054 +L G+P +V W+ +G L H + + G V ++ D G+Y C A+N Sbjct: 400 RLTVTGNPKPEVTWYKDGTQL-HDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPL 458 Query: 4055 GMDET--KAVIKTTGKPGIVYDSQLPKHMK-------SIE---------KIREMEASWQV 4096 G + K + G ++ +P ++ S+ K++ V Sbjct: 459 GSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSV 518 Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156 T + KA+ P F+ + VT E E F + G+P+P V W I +G R Sbjct: 519 TSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGR 578 Query: 4157 YKLT---YDGMYHFDIPKTRQYDTGKIEVI 4183 + ++ + MY I + R D+G + + Sbjct: 579 FTISESEENDMYSLVIDEARTEDSGPYKCV 608 Score = 47.6 bits (108), Expect = 2e-04 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 2/121 (1%) Query: 2615 SWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNL 2674 S++ + A V T + AP F + + EGQ+ + R P+ Sbjct: 2068 SYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTIRARPSPD- 2126 Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +EW+K L + ++ GL L I DD+G Y CKATN +G + + Sbjct: 2127 -VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRIIVDV 2185 Query: 2735 E 2735 E Sbjct: 2186 E 2186 Score = 47.6 bits (108), Expect = 2e-04 Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 2/99 (2%) Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165 K P + L +EE + ++ C V+G PKP++ W NG + + R + YDG+ Sbjct: 2931 KGEAPSFSLELRPIAAIEEFD-SKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIV 2989 Query: 4166 -HFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRH 4203 + I + D G E I L V R+ Sbjct: 2990 AYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRRN 3028 Score = 47.6 bits (108), Expect = 2e-04 Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 4/122 (3%) Query: 3670 ESIQKLEETLHKRE-EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMR 3728 E+ KL T K + +I + P P F ++ + EG V F C+V G P Sbjct: 5223 EATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLLPQ-NAREGDVVKFSCKV--TGYPEPE 5279 Query: 3729 IDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788 I+W +G + RV T D L I D+G Y C N G A+++A++ Sbjct: 5280 IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVG 5339 Query: 3789 AK 3790 K Sbjct: 5340 GK 5341 Score = 47.6 bits (108), Expect = 2e-04 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-G 692 Y P+ LK + A EGG+ F+ + G P +++W + I +R++S G Sbjct: 5637 YSKPEINEKLKKIEAFEGGEARFDLLV--TGFPPPRVDWYRGTTKITDCNRYSSTLTSDG 5694 Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 SL + + +D G Y C AV+ G + LHV Sbjct: 5695 MASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHV 5730 Score = 47.2 bits (107), Expect = 3e-04 Identities = 38/128 (29%), Positives = 58/128 (45%), Gaps = 9/128 (7%) Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEGQRAH 1596 ST I Q++ G ++++ D T ++ A P ++NVE EG A Sbjct: 240 STLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAF 299 Query: 1597 FERRL--IPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTC 1652 FE + P+ K EW+H++K ++ SRF T + +L I +DSG Y C Sbjct: 300 FEVKFKGYPIP----KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQC 355 Query: 1653 RAINALGE 1660 A N GE Sbjct: 356 IASNEAGE 363 Score = 47.2 bits (107), Expect = 3e-04 Identities = 23/87 (26%), Positives = 40/87 (45%) Query: 68 EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127 +P+ P + +N +G +A FE K +G P P W + +++ + ++ Sbjct: 277 KPAKPEVVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQ 336 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGE 154 SL+I + D G Y C A N+ GE Sbjct: 337 TSSLVISDLRLDDSGAYQCIASNEAGE 363 Score = 47.2 bits (107), Expect = 3e-04 Identities = 34/114 (29%), Positives = 50/114 (43%), Gaps = 5/114 (4%) Query: 1027 SRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086 S YS + VK KP L +K I G+ A F+ +++ VEWY +I Sbjct: 1688 STYSSANLDIVKSKSKPEILETMKDAEGIETGK-AKFDVKIKAYPKAE--VEWYHRSARI 1744 Query: 1087 TSANRIQTYHDF--GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 R D G ++ I +R ED G Y +VA N G+ A +TV+ + Sbjct: 1745 YDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798 Score = 47.2 bits (107), Expect = 3e-04 Identities = 36/116 (31%), Positives = 52/116 (44%), Gaps = 8/116 (6%) Query: 2227 GHSTR---IEVEEPKI--SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHN 2281 G +TR +E+E PK P F T L+ V EG+ F C+V +P+ + +Y N Sbjct: 1883 GSATRNFNVEIEVPKARDEAPSFTTTLK-PIDVTEGENHTFICRVHARPEPS--VTWYRN 1939 Query: 2282 GKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 + R TFD L +Q +DAG+Y A N +G MTV + Sbjct: 1940 KNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995 Score = 47.2 bits (107), Expect = 3e-04 Identities = 21/92 (22%), Positives = 43/92 (46%), Gaps = 3/92 (3%) Query: 4095 QVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154 + + + +V ++ P + P + + EG +RF R+ GHP P V W + +G Sbjct: 2513 EASSKALVGVNRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLTDG 2572 Query: 4155 SRYKLTYD---GMYHFDIPKTRQYDTGKIEVI 4183 +Y++ + G+Y + K + TG ++ Sbjct: 2573 VKYRIESNPEIGLYSLVVSKVQLDQTGHYRIV 2604 Score = 47.2 bits (107), Expect = 3e-04 Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 4/97 (4%) Query: 1842 QAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899 QAP F+ + K S +GQ + + P P+ + WY +G+ L R + Sbjct: 2831 QAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPH--ITWYKDGEPLDDTRRIDIRSRG 2888 Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 L IL + ED+G YTC+A N +G A S ++V Sbjct: 2889 NVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925 Score = 47.2 bits (107), Expect = 3e-04 Identities = 33/112 (29%), Positives = 57/112 (50%), Gaps = 8/112 (7%) Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLT--PTDDPNLKVEWYWNGKSLKAG 3466 D + + KG+AP F++ L I + E F+++L + P +++W NGK +++ Sbjct: 2924 DVTAPKVKGEAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESD 2978 Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518 R RT D L I +D+G Y C A N G ++A++ V +RN+ Sbjct: 2979 GRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTV-SRRNM 3029 Score = 47.2 bits (107), Expect = 3e-04 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 2/94 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F +++ E + C V K PK +I+W +NGK + S R RT YD L Sbjct: 2935 PSFSLELRPIAAIEEFDSKLICHVSGK--PKPQIKWTKNGKPVESDGRLRTDYDGIVAYL 2992 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 I V +D+G Y C A N G + A ++ + Sbjct: 2993 SIWQVSHDDAGTYECIASNAAGTVSSSAALTVSR 3026 Score = 47.2 bits (107), Expect = 3e-04 Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 4/91 (4%) Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT--SIFRFGYISLDMLS 700 L + A EG + F+ IE G P+ +EW K I R+ S G SL + Sbjct: 3037 LHDMKAYEGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSD 3094 Query: 701 LNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 LN D G Y C A + G A T+A+L V R Sbjct: 3095 LNADDDGIYKCVAQNLAGKASTRAMLDVIAR 3125 Score = 47.2 bits (107), Expect = 3e-04 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 2/96 (2%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 +P+F + + V E F A + G P ++W ++ PI +++R+ T D V Sbjct: 3981 SPIFVTELSPLSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVK 4038 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 L + + ED G Y NE G A +S+ L V+ + Sbjct: 4039 LLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREE 4074 Score = 47.2 bits (107), Expect = 3e-04 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 5/102 (4%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F + ++S V E E F C V P RI+W+ N + + R T D L Sbjct: 4455 PGFKSALRSLDVTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPVHKL 4512 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS---CKKLPDII 3928 I +D+G Y C AVND G + A ++ C+ P + Sbjct: 4513 AITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFV 4554 Score = 47.2 bits (107), Expect = 3e-04 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P F L+ L ++ E +A F +++ P R++W+ + +P++ SRI + + Sbjct: 4455 PGFKSALRSL-DVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863 L I +D G Y AVN G A STA + V+ Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVS 4545 Score = 47.2 bits (107), Expect = 3e-04 Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 3/95 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +AP F L + EG V +V +P +IEW ++GV++ + R+ + +D Sbjct: 5247 KAPAFLKQLLPQNAR-EGDVVKFSCKVTGYPEP--EIEWTRDGVSMESDERVTTWYDGEH 5303 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 TLSI++ + DSG+Y C N G A S+A + + Sbjct: 5304 STLSIHNANHADSGMYKCTLKNNSGWASSSAELVV 5338 Score = 47.2 bits (107), Expect = 3e-04 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP F+ L +I+ +EG + G VEW+ + +P+ HR R + V Sbjct: 5543 APAFTAPLQHIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L L D+GV+ C N LG +S +L V Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633 Score = 46.8 bits (106), Expect = 4e-04 Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969 KPE ++ + VEG E V+ K P K EW+ + K +E SRFK+T+D Sbjct: 280 KPE-VVRKMENVESVEGSDAFFE--VKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQ 336 Query: 2970 TLDLV--DVYERDSGIYTCKAYNKRGE 2994 T LV D+ DSG Y C A N+ GE Sbjct: 337 TSSLVISDLRLDDSGAYQCIASNEAGE 363 Score = 46.8 bits (106), Expect = 4e-04 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 4/85 (4%) Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS--INSLRNDDS 2712 VEG + E + + P K EWF + + +R K T D T S I+ LR DDS Sbjct: 293 VEGSDAFFEVKFKGYPIP--KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDS 350 Query: 2713 GIYTCKATNLLGEAVSTASIKIEDR 2737 G Y C A+N GE A +K++++ Sbjct: 351 GAYQCIASNEAGECNLRADLKVKNK 375 Score = 46.8 bits (106), Expect = 4e-04 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 4/106 (3%) Query: 1837 EVAVN--QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894 E+ VN + I +++ ++SEG +A E ++ P P VEWY + G R++ Sbjct: 1989 EMTVNKREVKPVIKEVSKTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQ 2046 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 + + + L I V + + Y C A NN G+ L + +E Sbjct: 2047 VTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITERE 2092 Score = 46.8 bits (106), Expect = 4e-04 Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 3/124 (2%) Query: 1816 SALQKIQQLEDSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874 +A K ++ R R D+ + + AP F + EGQ+A I P P Sbjct: 2066 AASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTIRARPSP 2125 Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934 + VEWY +L S + G L+I +D+G Y CKA N++G I + Sbjct: 2126 D--VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRIIV 2183 Query: 1935 NVQS 1938 +V++ Sbjct: 2184 DVEA 2187 Score = 46.8 bits (106), Expect = 4e-04 Identities = 27/96 (28%), Positives = 43/96 (44%) Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698 QQAP+F S +K Q + P I W+K+G L R+ Sbjct: 2830 QQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRIDIRSRGN 2889 Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 + L I +L+ +D+G YTC+A N +G A + + + Sbjct: 2890 VYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925 Score = 46.8 bits (106), Expect = 4e-04 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 2/92 (2%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P+F L++++ EG + L C++ G VEWF + + I R R + + L Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTL 3744 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 +V +D G Y C ATNQ G +S + V Sbjct: 3745 IFETVNIQDRGAYRCTATNQEGSTSSSAVIVV 3776 Score = 46.8 bits (106), Expect = 4e-04 Identities = 33/94 (35%), Positives = 42/94 (44%), Gaps = 4/94 (4%) Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTT--MHDFGYVALN 1771 T M ++ E + R+ G P VEW R I R T M D G +L Sbjct: 4260 TSKMANVTAVEGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLI 4317 Query: 1772 MKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + V EDSG+Y A N LGEA T + L V+ K Sbjct: 4318 ISDVQLEDSGSYRAVASNNLGEATTLAELTVKGK 4351 Score = 46.8 bits (106), Expect = 4e-04 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP F + L+S D + E + +V P +I+WF N ++ +R+ ++ D + Sbjct: 4454 APGFKSALRSLD-VTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPVH 4510 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L+I D+G+Y C A N G A STA + + Sbjct: 4511 KLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 46.8 bits (106), Expect = 4e-04 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 2/90 (2%) Query: 4095 QVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154 Q P++ V+ + P + + DA EEG RF V HP P V W + +G Sbjct: 5037 QAVPKEEVDHGQIVKPVITRKIRDAQG-EEGSNIRFEIHVKSHPPPHVEWYRGSIKLAHG 5095 Query: 4155 SRYKLTY-DGMYHFDIPKTRQYDTGKIEVI 4183 +Y+++ DG Y I ++ DTG +V+ Sbjct: 5096 PKYQISEGDGAYSLTITGVQKDDTGSYKVV 5125 Score = 46.8 bits (106), Expect = 4e-04 Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 4/104 (3%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT-T 960 V E KPE +K +I EGG A F+ L G RV+W + + +R + T Sbjct: 5633 VNEGYSKPEINEKLK-KIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSST 5689 Query: 961 FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 + G +LTI+ + D G Y C A N G+ T+ +L + K Sbjct: 5690 LTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733 Score = 46.4 bits (105), Expect = 6e-04 Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 5/96 (5%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIFNFG 826 +P+ +R ++++ E EG +A FE + P + EW+ D + I SSR IT+ Sbjct: 280 KPEVVRKMENV-ESVEGSDAFFEVKFKGY--PIPKREWFHDSKKIEPSSRFKITTDDTEQ 336 Query: 827 YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 SL I LR +D+G+Y A N+ GE A ++V Sbjct: 337 TSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV 372 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 7/112 (6%) Query: 1832 RREDVEVAV----NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887 R D++V V + P T++ + +G+ C + P+P VEW+ +GK L Sbjct: 714 RSFDIKVKVAEPQGETPTITTEMTDIQAI-DGEDCKLICHVTGEPNPE--VEWFKDGKPL 770 Query: 1888 QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 ++ HR S + AL + ED G Y C N G S+ + V+ + Sbjct: 771 KANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P T I+ I+G+ C + + N +VEWFK+G+P+ HR P + +A Sbjct: 730 PTITTEMTDIQ-AIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMIA 786 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGT 1527 L + ED G Y C N+ G+ Sbjct: 787 LSFRPIKLEDMGRYKCVISNVFGS 810 Score = 46.4 bits (105), Expect = 6e-04 Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 3/102 (2%) Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159 ++ E +P +T++ + ++E + A F C +P I+WF I G R+ Sbjct: 817 VKVEDRSLKPEVITSMRDCDCVEE-ETASFHCEFSGKPEPE--IEWFCGPNPIVPGGRFH 873 Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 T + +L I ED+G Y C A+N G+ LKV Sbjct: 874 VTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKV 915 Score = 46.4 bits (105), Expect = 6e-04 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY-V 1768 AP F +RV E + A + G PK V W ++ V I +R ++ G Sbjct: 1214 APSFHGRQGRLRVKEGREASVYFEIS--GKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSY 1271 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819 +K PED GTY C A N++G A + + V+ K + + + LQ Sbjct: 1272 YFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQ 1322 Score = 46.4 bits (105), Expect = 6e-04 Identities = 58/216 (26%), Positives = 87/216 (40%), Gaps = 37/216 (17%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 +P + ++++ + EG A F+ +L G P+ +EW+ I D R + D Sbjct: 1410 KPEVLEKMKDVKGV-EGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGRYKFSRDDQKY 1466 Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494 S+TI + +D G Y C ASN G+ TQ E ++ E+ + Sbjct: 1467 SLTIKDLNLQDIGTYKCIASNEAGKV-----------------TQRAE----LEVKERDY 1505 Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554 EE ++F +P+ QV P E+ Y R G P W+ NG EL+ G Sbjct: 1506 APIFEE--KQFLEPLEIQV-RQPVEV------SYHVR----GRPKPTVTWWKNGKELRDG 1552 Query: 2555 SRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 + TL I DAG Y C A N G Sbjct: 1553 KHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVG 1588 Score = 46.4 bits (105), Expect = 6e-04 Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 8/103 (7%) Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLV--PVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337 E P F +++ + + E F+++L+ P +++W NGK + R RT +D Sbjct: 2933 EAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDG 2987 Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380 + L I +++G YEC+A+N G S+ A L S+ N+ Sbjct: 2988 IVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAAL-TVSRRNM 3029 Score = 46.4 bits (105), Expect = 6e-04 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRI--EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694 P F + L+ + A+E F++++ G P +I+W KNG+ +E+ R + + Sbjct: 2935 PSFSLELRPIAAIE----EFDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIVA 2990 Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 L + ++ D+G Y C A +A G + A L V+ R Sbjct: 2991 YLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027 Score = 46.4 bits (105), Expect = 6e-04 Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 5/101 (4%) Query: 767 SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF- 825 + RP L D+ + EG+ A F+ ++T PT VEW+K I+ R + N Sbjct: 3028 NMRPLITHKLHDM-KAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEE 3084 Query: 826 -GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 G SL + L A+D G Y A N G+A + A + V AR Sbjct: 3085 QGKHSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIAR 3125 Score = 46.4 bits (105), Expect = 6e-04 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 4/87 (4%) Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK--STFDFGLVTLSINSLRNDDS 2712 VEG V + ++ P+ +EW++ + L + K T + GL +L +N + DD Sbjct: 3500 VEGWKVQFQTRITGYPYPH--VEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDI 3557 Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHW 2739 G Y C ATN G + ++ ++D+ + Sbjct: 3558 GTYKCLATNSAGSSACRINLDVKDKQY 3584 Score = 46.4 bits (105), Expect = 6e-04 Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 4/100 (4%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+F+ L L ++ EG +A ++ +PT VEW+KD + IT + R+ S + Sbjct: 3687 PKFLSHLNSL-DVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCT 3743 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVT 869 L + +D G+Y A N+ G S+A I V R+++T Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVI-VVNRASIT 3782 Score = 46.4 bits (105), Expect = 6e-04 Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 6/101 (5%) Query: 1171 EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT-- 1228 E+ KP ++N V EG + L+ R+ G P VEWF +T G R+KT Sbjct: 4252 EVQACKPQ-TSKMANVTAV-EGWKVQLDTRMT--GYPVPIVEWFRGEEKITDGGRYKTAR 4307 Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269 D G +L I D+G Y A N+LG A T A + V Sbjct: 4308 MEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTV 4348 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 2/64 (3%) Query: 3591 VEWFHNGKPLLTGSRVKT--INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ 3648 VEWF + + G R KT + D G L I V D+G Y A+N GEAT +L Sbjct: 4288 VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELT 4347 Query: 3649 VKGR 3652 VKG+ Sbjct: 4348 VKGK 4351 Score = 46.4 bits (105), Expect = 6e-04 Identities = 35/150 (23%), Positives = 60/150 (40%), Gaps = 3/150 (2%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141 +EW+ + + + G L I G + D+G+Y ATN+ G + ++ Sbjct: 5083 VEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVVVK 5142 Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201 DK K T I + G + T+ P + WY +G + S ++ Sbjct: 5143 DKPLAPKVAEMTATGPIT-ITRGNQLNLNVTIR--GKPKPSVVWYKDGNKILTSRNVQIR 5199 Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 S L I +T++ +G Y C A +K G Sbjct: 5200 SCGDVYHLIILFTKSEHAGTYSCEATSKLG 5229 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Query: 2366 EIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI 2425 + PE + P F + L N +EG F C++ G P ++EW R+ +E R+ Sbjct: 5240 QAPEAAPKA-PAFLKQLLP-QNAREGDVVKFSCKV--TGYPEPEIEWTRDGVSMESDERV 5295 Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 T +D + +++I + D G+Y C N G Sbjct: 5296 TTWYDGEHSTLSIHNANHADSGMYKCTLKNNSG 5328 Score = 46.4 bits (105), Expect = 6e-04 Identities = 40/148 (27%), Positives = 66/148 (44%), Gaps = 5/148 (3%) Query: 1660 EAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV--ITQAPVFTMPM 1717 E VT+ HS SI+ + + + + L++ S + SA+ V TQ P + M Sbjct: 5293 ERVTTWYDGEHSTLSIHNANHADSGMYKCT-LKNNSGWASSSAELVVGGKTQRPRLSDNM 5351 Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777 K++ A FE + PK ++ W ++ + + + +R T + G L +K V Sbjct: 5352 KELFATVGGEARFEVTM--KATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQL 5409 Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSK 1805 DSGTY A N+ G+ L V K Sbjct: 5410 SDSGTYKFVASNKAGKTTFLGYLEVMEK 5437 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 5/100 (5%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET-NNFGFVA 1636 P LK +E EG A F+ L+ +V+WY + +R++ T + G + Sbjct: 5640 PEINEKLKKIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMAS 5697 Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY 1676 L I ED G Y C A+N GE T+ I +H + Y Sbjct: 5698 LTIRKIRQEDGGLYGCVAVNEYGE--TTSIVDLHVGEKHY 5735 Score = 46.0 bits (104), Expect = 8e-04 Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 1/94 (1%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169 P F+S + + + EG+ + C VTG P+P V W + I R+K +YDG + + Sbjct: 1021 PTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTV 1080 Query: 4170 PKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRH 4203 + D G + + + V+ +H Sbjct: 1081 KEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH 1114 Score = 46.0 bits (104), Expect = 8e-04 Identities = 84/362 (23%), Positives = 134/362 (37%), Gaps = 71/362 (19%) Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288 S +++ + K S P + ++ + GK A F+ +++ P +E+YH + Sbjct: 1692 SANLDIVKSK-SKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDG 1747 Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPE 2348 R+ +T D E+ G YSV IN L + + A I S+R E Sbjct: 1748 GRYCLTQD-------------EEDGTYSV-TINDL-RLEDCGTYKIVAFNDIGKTSERAE 1792 Query: 2349 GLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTL 2408 ++E A F+ E P + + NI+ G P+ Sbjct: 1793 --LTVKEKLIAPEFEGRETEVPFRAKEKSDLEVSYNIN-----------------GKPSP 1833 Query: 2409 KVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXX 2468 V W+R+++L+ D + T+ +V D G Y C A N +G Sbjct: 1834 DVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVG---------- 1883 Query: 2469 XXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528 +E + P+ R E P FT L P ++ EG++ + Sbjct: 1884 SATRNFNVEIEVPKA-------------RDEAPS-------FTTTLK-PIDVTEGENHTF 1922 Query: 2529 EARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINR 2588 RV +PS+ WY N E+ R RTT D L + + DAG Y C A N Sbjct: 1923 ICRVHARPEPSV--TWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNP 1980 Query: 2589 AG 2590 G Sbjct: 1981 IG 1982 Score = 46.0 bits (104), Expect = 8e-04 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 3/109 (2%) Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604 V+ P+A P FTTT + ++E + F CR+ + S V W+ N ++ Sbjct: 1891 VEIEVPKARD-EAPSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDG 1947 Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653 R +T D L + + +DAG Y C A+N G+A + ++ V R+ Sbjct: 1948 RSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKRE 1996 Score = 46.0 bits (104), Expect = 8e-04 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 3/110 (2%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 KP + K EV+EG +E ++ V PT VEWY V G RF+ T + Y Sbjct: 1998 KPVIKEVSKTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHT 2055 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDEQRL 2085 L I + +Y C A N G + + + + + + DE+R+ Sbjct: 2056 LSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRI 2105 Score = 46.0 bits (104), Expect = 8e-04 Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 5/112 (4%) Query: 3682 REEITIEDEKPNPPRFTVE--IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA 3739 R E+ I+ EK P F E ++ +P+G ++ V G PT I W+ +G P Sbjct: 2821 RGELHIK-EKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTV--TGSPTPHITWYKDGEPLD 2877 Query: 3740 TGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791 R+ + L I + DAG YTC A N+ G+A + ++ +A + Sbjct: 2878 DTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPK 2929 Score = 46.0 bits (104), Expect = 8e-04 Identities = 31/108 (28%), Positives = 46/108 (42%), Gaps = 3/108 (2%) Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604 VD P+ + G P F+ + E + C + +++W NGKP+ + Sbjct: 2923 VDVTAPKVK-GEAPSFSLELRPIAAIEEFDSKLICHVS--GKPKPQIKWTKNGKPVESDG 2979 Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 R++T D L I V DAG Y C A+N G + S L V R Sbjct: 2980 RLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027 Score = 46.0 bits (104), Expect = 8e-04 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 3/98 (3%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 +PIF T L + EG + A V P+ I+W+K+ +++ R+++ FD +V Sbjct: 3981 SPIFVTELSPLS-VTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFFDGHVV 4037 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738 L I + +D G Y N G A S+A + + + + Sbjct: 4038 KLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEY 4075 Score = 46.0 bits (104), Expect = 8e-04 Identities = 22/68 (32%), Positives = 38/68 (55%) Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796 +G+P+ V W ++GV + ++R+ LN+ + P+D+GTY C A + LG Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236 Query: 1797 SSTLFVQS 1804 S TL V++ Sbjct: 4237 SCTLDVKA 4244 Score = 46.0 bits (104), Expect = 8e-04 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 2/93 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F L+S+ E F R E G P +I+W N Q + SR + L Sbjct: 4455 PGFKSALRSLDVTEDESAEF--RCEVSGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKL 4512 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729 + +QD+G Y C AV+ G A + A L+V+ Sbjct: 4513 AITKATLQDTGVYKCLAVNDNGSATSTADLNVS 4545 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 5/106 (4%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 PQ Q+ E+ EG + + + LT P V WYKDG+P+ + I Sbjct: 88 PQIKEKEQEPIEVFEGESVNLD--LTITGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF 145 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS---TVTADL 872 L+I D+G Y A NK+G + + V + TVT++L Sbjct: 146 LSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSEL 191 Score = 45.6 bits (103), Expect = 0.001 Identities = 59/242 (24%), Positives = 94/242 (38%), Gaps = 30/242 (12%) Query: 1310 APQFSRA-LHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 AP+F+ L IE E V++ RL G+ V W+ +G + + + D Sbjct: 378 APEFADGDLEPIEVKEDQAVNV--RLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVH 435 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK--KDLILESQHPSGLEK------ 1420 L + D G Y C+A+N LG + + V+ K +I P + K Sbjct: 436 ELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKW 495 Query: 1421 --IQYLEDTSRYK------------KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFEC 1466 L+D YK DI + +KP F+ + + + +E + V FE Sbjct: 496 SVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDV-TALETEQVWFEI 554 Query: 1467 KLEPVTDSNLKVEWFKNGQPVTIGHRF--RPIHDFGYVALDIIDLIAEDSGIYTCRAVNL 1524 ++ VEW++ + G RF + +L I + EDSG Y C A N Sbjct: 555 PIQGY--PRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASND 612 Query: 1525 VG 1526 G Sbjct: 613 AG 614 Score = 45.6 bits (103), Expect = 0.001 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 3/89 (3%) Query: 1438 ESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH 1497 E ++KP +T + + +E + F C+ + ++EWF P+ G RF Sbjct: 820 EDRSLKPEVITSMRDCD-CVEEETASFHCEFSGKPEP--EIEWFCGPNPIVPGGRFHVTE 876 Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 + +L I DL ED+G Y C A N G Sbjct: 877 EGNIQSLAISDLKLEDAGNYKCVASNAAG 905 Score = 45.6 bits (103), Expect = 0.001 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 +P +++ D ++E +TA F C G P ++EWF I R T + Sbjct: 825 KPEVITSMRDCDCVEE-ETASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQ 881 Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459 S+ IS ++ ED G Y C ASN G+ Sbjct: 882 SLAISDLKLEDAGNYKCVASNAAGK 906 Score = 45.6 bits (103), Expect = 0.001 Identities = 48/227 (21%), Positives = 93/227 (40%), Gaps = 39/227 (17%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-S 695 P+F ++ A++G ++ T + G P +I WLK+G+ + ++ I +G + Sbjct: 922 PEFEDWKDTIDALDGQDVNISTWVR--GKPKPEIVWLKDGEELR-NTMHVQIKCYGDLHG 978 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755 L + ++ +D+G YTCRA + G+ + T+E + +T ++ +LE Sbjct: 979 LVLYKVSPEDAGMYTCRAKNNAGIVSKDVTI------TVEALQKKGDTPTFMSKLE---- 1028 Query: 756 YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815 P++ + EG + +T P V+W++D I Sbjct: 1029 -------------------PIE----ITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKP 1063 Query: 816 SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 S R + ++ +L + +D G Y N G S A + V Sbjct: 1064 SRRFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV 1110 Score = 45.6 bits (103), Expect = 0.001 Identities = 21/79 (26%), Positives = 38/79 (48%) Query: 4085 EKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144 E ++ +++ P V + + P A V EG+ R C+V+G+P+P + W Sbjct: 1289 EARNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEW 1348 Query: 4145 LLNGNTIVNGSRYKLTYDG 4163 L N + + R+K +DG Sbjct: 1349 LKNNELLSDNDRFKTRFDG 1367 Score = 45.6 bits (103), Expect = 0.001 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 9/129 (6%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 +EV++ + P +L+ V EG C+V +P L E+ N + L RF Sbjct: 1305 VEVKQEVMIAPEIRQQLQAED-VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRF 1361 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 FD +L I++ DA Y V N G +S +AK +I + +PE LE Sbjct: 1362 KTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSS------SAKLKVIRKCTKPEVLE 1415 Query: 2352 KIRELESAE 2360 K+++++ E Sbjct: 1416 KMKDVKGVE 1424 Score = 45.6 bits (103), Expect = 0.001 Identities = 62/247 (25%), Positives = 100/247 (40%), Gaps = 29/247 (11%) Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912 P ++EG+ A + + P VEW+ +GK L R + L I V E Sbjct: 3139 PVIVNEGEEA--QMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPE 3196 Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS--QHESALEKIQYLE-DDSRYKRAV- 1968 D G Y C A + G++ + L+V+ + + S S L ++ LE + +++ V Sbjct: 3197 DEGSYKCVASSTNGRSSRTFDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVS 3256 Query: 1969 ----------QDDSFVVEKPQF-----GK----PIKNAEVTEGHPVHLEATLTPVNDPTM 2009 +DD+ + + +F G+ + + E LEA + V PT Sbjct: 3257 GEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPT- 3315 Query: 2010 RVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 VEW+ + G R++ L I + EDTG Y ATN G T S V + Sbjct: 3316 -VEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGS--TGSVVDL 3372 Query: 2070 DAKSGLY 2076 K L+ Sbjct: 3373 TVKERLF 3379 Score = 45.6 bits (103), Expect = 0.001 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 4/73 (5%) Query: 1456 VIEGQHVHFECKLEPVTDSNL-KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514 V EG+ E + +T + L KVEWFKN +PV H R D + L + ED+ Sbjct: 4764 VTEGESTALEVE---ITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDA 4820 Query: 1515 GIYTCRAVNLVGT 1527 G+Y C +N +GT Sbjct: 4821 GLYRCTILNDLGT 4833 Score = 45.6 bits (103), Expect = 0.001 Identities = 62/227 (27%), Positives = 90/227 (39%), Gaps = 37/227 (16%) Query: 1310 APQFS--RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367 AP+F L + VEG V L ++ G V+W+ GK + T + D Sbjct: 5440 APEFPDRETLEQVVGVEGREVELSTVVK--GLPRPSVKWYKEGKLLHTSKALTVSTSGDT 5497 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427 + + S E SG Y C+ATN G A +D +L Q E+ T Sbjct: 5498 HYVWIPSAKHEHSGRYRCEATNSNGT----------AHRDFVLNIQAQVPAEQWVAPAFT 5547 Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487 + + DI++ T RF+ I G V PV VEW+++ +PV Sbjct: 5548 APLQHIDILEGDTT---RFIGE-------ITGVPV-------PV------VEWYRDDRPV 5584 Query: 1488 TIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 T HR R D V L + D+G++ C N +GT S L Sbjct: 5585 TRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASL 5631 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/103 (30%), Positives = 44/103 (42%), Gaps = 4/103 (3%) Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH-TL 3747 +E + P ++K I+ EGG FD V G P R+DW+ +R TL Sbjct: 5634 NEGYSKPEINEKLK-KIEAFEGGEARFDLLV--TGFPPPRVDWYRGTTKITDCNRYSSTL 5690 Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 G +L I I D G Y C A N++G T+ + K Sbjct: 5691 TSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733 Score = 45.2 bits (102), Expect = 0.001 Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 6/109 (5%) Query: 1301 VREDITVMQ---APQFS-RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356 +R D++V + APQ + IE EG +V+L+ + G V W+ +GKP++ Sbjct: 75 LRGDLSVKEKQIAPQIKEKEQEPIEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKT 132 Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 D L + P DSG Y C+A N++G + + V K Sbjct: 133 KSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVK 181 Score = 45.2 bits (102), Expect = 0.001 Identities = 27/95 (28%), Positives = 52/95 (54%), Gaps = 8/95 (8%) Query: 2366 EIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLI--PVGDPTLKVEWFRNEKLIEDSS 2423 ++ EP + P T + +I I +G+ DC+LI G+P +VEWF++ K ++ + Sbjct: 721 KVAEP-QGETPTITTEMTDIQAI-DGE----DCKLICHVTGEPNPEVEWFKDGKPLKANH 774 Query: 2424 RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 R+ + + ++++ ++ ED G Y C SN+ G Sbjct: 775 RLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFG 809 Score = 45.2 bits (102), Expect = 0.001 Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 10/139 (7%) Query: 3685 ITIE--DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742 IT+E +K + P F +++ I++ EG C V G P + WF + Sbjct: 1009 ITVEALQKKGDTPTFMSKLEP-IEITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSR 1065 Query: 3743 RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQG 3802 R D AL + D G Y C TN +GS ++ A +T K L ++ Q Sbjct: 1066 RFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH---LRPEVLQK 1122 Query: 3803 MSGEKIKELERGRISDAPK 3821 M + ++ +E G+ + A K Sbjct: 1123 M--DDVRTVEGGKANFAVK 1139 Score = 45.2 bits (102), Expect = 0.001 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 2/97 (2%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P F +K +VTEG + +P+ V WY N + R +TT+D Sbjct: 1901 EAPSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETY 1958 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 L + +D G Y C A+N +G+A T+ + V+ + Sbjct: 1959 KLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995 Score = 45.2 bits (102), Expect = 0.001 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 4/109 (3%) Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288 + + V + ++ P + E+ T V EG TA E +V V P +E+YH + Sbjct: 1987 TAEMTVNKREVKP--VIKEVSKTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDG 2042 Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 RF +T + Y +L I+ + A Y A N G T + +T + Sbjct: 2043 DRFQVTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITER 2091 Score = 45.2 bits (102), Expect = 0.001 Identities = 83/352 (23%), Positives = 138/352 (39%), Gaps = 69/352 (19%) Query: 921 IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980 +++GGF + L +G+ V W KDG + +SR I V D G Sbjct: 2640 VRKGGFVNITFTL--MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTG 2697 Query: 981 HYTCRAYNAIGQATTSANLTIVTKKDIIA-ESQHPGGLEKIQYLEDASRYSKRTEEEVKI 1039 Y C A+N +G + S + I K + + +++ PG L + + Sbjct: 2698 TYVCEAHNRLGSSFRSCTIEIKEPKSVDSTDTRAPGQL-------------------IPV 2738 Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHD 1097 K F G V G A + V+ +SD+ + +EW+ + ++ I D Sbjct: 2739 KHKFDFEG--------VPGGKARCDVLVK-KSDI-IDIEWFRGTNMLRDGDKYKILKSDD 2788 Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157 ++L + +V ED+G Y V AG+ + + ++ + L EK + Sbjct: 2789 GQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHIKEKQQAPLF-----LDEK---V 2840 Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217 + KF P Q +E++KS V P + +G EP+ D Sbjct: 2841 SQEKFSLP--QGQEMNKSFTVTGSPTPHITWYKDG---------EPLDDT---------- 2879 Query: 1218 RSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269 R + + SR YY L I++ D G YT A N +G+A+ S V V Sbjct: 2880 RRIDIRSRGNVYY------LGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925 Score = 45.2 bits (102), Expect = 0.001 Identities = 24/69 (34%), Positives = 32/69 (46%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G T + W KDG P++ + RI L I ++ DAG YTC A N IG A S Sbjct: 2861 GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920 Query: 997 ANLTIVTKK 1005 + + K Sbjct: 2921 FEVDVTAPK 2929 Score = 45.2 bits (102), Expect = 0.001 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 2/113 (1%) Query: 2751 DRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWF 2810 +RIGA F L I E + C+V S P +I+W Sbjct: 2912 NRIGAAYRSFEVDVTAPKVKGEAPSFSLELRPIAAIEEFDSKLICHV--SGKPKPQIKWT 2969 Query: 2811 FNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 N KP+ S R ++ +D L I +D+G Y C A+N+ G+ ++S +L Sbjct: 2970 KNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAAL 3022 Score = 45.2 bits (102), Expect = 0.001 Identities = 65/252 (25%), Positives = 100/252 (39%), Gaps = 19/252 (7%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 ++K P F+ L +E L EGE F ++ +P VEW+ + +K RFRT+ Sbjct: 3226 KDKWSLPAFSSKLRPLETL-EGEKTKFVVNVS--GEPIPTVEWFKDDTPIKHEDRFRTYF 3282 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT----ASMKV-QGKR-------NI--I 3519 D +L T + E A+ T S K+ G+R N+ + Sbjct: 3283 DGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTL 3342 Query: 3520 LESQLPKGMEGTIDKIAALE-GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFE 3578 + S L G IA E G +G+V LT + E PEF + Sbjct: 3343 VISNLHMEDTGPYKIIATNEHGSTGSVVDLTVK-ERLFGPEFLEEEGVWNKVAKAGGFVN 3401 Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638 + V W+ +G L +R+ + + I G+ DAG Y C+A +R Sbjct: 3402 ISFTLKGNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRI 3461 Query: 3639 GEATVSCKLQVK 3650 G A SC L++K Sbjct: 3462 GTAIRSCTLEIK 3473 Score = 45.2 bits (102), Expect = 0.001 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 3/91 (3%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P+F + +++DV EG C++ G P ++WF + + RV + Sbjct: 3687 PKFLSHL-NSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCT 3743 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 L + + +D G Y C ATN+ GS +++A I Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVI 3774 Score = 45.2 bits (102), Expect = 0.001 Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 32/203 (15%) Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781 +G+P + WF +G SR+ + L+I + DAG Y C A ++ G Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLG---- 4232 Query: 3782 TAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841 TC + +++ P+ RG A K + +++ + T Sbjct: 4233 ----TCFRSCTLDVKAVRPR-----------RGNEVQACKPQT---------SKMANVTA 4268 Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT--VYDMGFVSLDILYVYAEDS 3899 E V+ + R+ P +EW+R + + G RY+T + D G SL I V EDS Sbjct: 4269 VEGWKVQLDTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDS 4326 Query: 3900 GEYICRAVNDFGEDFTKATISCK 3922 G Y A N+ GE T A ++ K Sbjct: 4327 GSYRAVASNNLGEATTLAELTVK 4349 Score = 45.2 bits (102), Expect = 0.001 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVSLDI 2835 S + N+ EG + + + + P +EWF + + G RYK+ D SL I Sbjct: 4261 SKMANVTAVEGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLII 4318 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867 + EDSG Y A+N+ G ATT L G Sbjct: 4319 SDVQLEDSGSYRAVASNNLGEATTLAELTVKG 4350 Score = 45.2 bits (102), Expect = 0.001 Identities = 29/108 (26%), Positives = 57/108 (52%), Gaps = 4/108 (3%) Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636 AP ++L+++++ E + A F R + S A +++W+ N++P+ SR +++ Sbjct: 4454 APGFKSALRSLDVTEDESAEF-RCEVSGSPAP-RIQWFMNDQPVSRDSRIITSSDGPVHK 4511 Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAV-TSGIAIVHSK-KSIYLESQHE 1682 L I +D+G Y C A+N G A T+ + + H + K ++E E Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLRE 4559 Score = 45.2 bits (102), Expect = 0.001 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 3/89 (3%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P FV ++ + T++ E E+T E ++ G P KVEWF N KP+ H + +D + Sbjct: 4753 PSFVIEL-TPTTVTEGESTALEVEIT--GTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIR 4809 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKA 4061 + ED+G Y C N G + A Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMA 4838 Score = 45.2 bits (102), Expect = 0.001 Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 28/196 (14%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669 +V WY + L +R + L+I S ED+GTY C A + LG+ S I V Sbjct: 4977 EVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCILDV 5036 Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729 A+P+ E+ Q PV T ++D + E Sbjct: 5037 Q-------------AVPK----EEVDHGQ---------IVKPVITRKIRDAQGEEGSNIR 5070 Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789 FE + P VEW R + + + G +L + V +D+G+Y A N Sbjct: 5071 FEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATN 5128 Query: 1790 ELGEAVTSSTLFVQSK 1805 + G + + + + V+ K Sbjct: 5129 QAGSSTSRAEVVVKDK 5144 Score = 45.2 bits (102), Expect = 0.001 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 3/113 (2%) Query: 754 SKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI 813 +K+ Q E + P F++ L +EG F ++T +P +EW +DG + Sbjct: 5233 AKFDVQIQAPEAAPKAPAFLKQLLPQNA-REGDVVKFSCKVTGYPEP--EIEWTRDGVSM 5289 Query: 814 TASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866 + R+T+ ++ + +L+I + D+G Y N G A S+A + V ++ Sbjct: 5290 ESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKT 5342 Score = 45.2 bits (102), Expect = 0.001 Identities = 23/69 (33%), Positives = 42/69 (60%), Gaps = 4/69 (5%) Query: 2671 DPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728 +P + W+K+G+ L TT ++S D +T I L +DD+G Y C+A + LG++ Sbjct: 5765 NPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLT--IFGLTHDDTGTYVCEAQSRLGKSFR 5822 Query: 2729 TASIKIEDR 2737 T ++K+E++ Sbjct: 5823 TYALKVEEQ 5831 Score = 44.8 bits (101), Expect = 0.002 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 2/103 (1%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E P+ K ++ I + EG + + + G V W KDG+P+ + I Sbjct: 81 VKEKQIAPQIKEKEQEPIEVFEGESVNLDLTIT--GKPKPEVVWYKDGKPLRKTKSIDLK 138 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 L+I T +D+G Y C A N IG + ++ + K Sbjct: 139 STDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVK 181 Score = 44.8 bits (101), Expect = 0.002 Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 10/154 (6%) Query: 1413 QHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENV--IEGQHVHFECKLEP 1470 Q G K++ D T D VT KP + +ENV +EG FE K + Sbjct: 249 QDDKGTYKVEITNDLGSISST--ADLEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFKG 306 Query: 1471 VTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV--ALDIIDLIAEDSGIYTCRAVNLVGTD 1528 K EWF + + + RF+ D +L I DL +DSG Y C A N G Sbjct: 307 YPIP--KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAG-- 362 Query: 1529 EVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562 E + R + + LE I+V ED++ Sbjct: 363 ECNLRADLKVKNKPFAPEFADGDLEPIEVKEDQA 396 Score = 44.8 bits (101), Expect = 0.002 Identities = 38/139 (27%), Positives = 56/139 (40%), Gaps = 11/139 (7%) Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468 + VE+ K V T + + + + E E A F + +P ++EW+ + G R Sbjct: 816 EVKVEDRSLKPEVIT-SMRDCDCVEE-ETASFHCEFSGKPEP--EIEWFCGPNPIVPGGR 871 Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGM 3528 F + L IS ED+G Y C A N G+ T A +KV E Sbjct: 872 FHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVN-------EKHFAPEF 924 Query: 3529 EGTIDKIAALEGYSGTVDT 3547 E D I AL+G + T Sbjct: 925 EDWKDTIDALDGQDVNIST 943 Score = 44.8 bits (101), Expect = 0.002 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 3/103 (2%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V + + KPE T ++D ++E A F G +EW P+ R Sbjct: 819 VEDRSLKPEVITSMRDCDCVEEET-ASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVT 875 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 +L I + + DAG+Y C A NA G+ TT A L + K Sbjct: 876 EEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 44.8 bits (101), Expect = 0.002 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P IT + + E ++A + C P+P +EW+ + G R+ + + + Sbjct: 826 PEVITSMRDCDCVEE-ETASFHCEFSGKPEPE--IEWFCGPNPIVPGGRFHVTEEGNIQS 882 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 L I + ED+G Y C A N G+ + L V K Sbjct: 883 LAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 44.8 bits (101), Expect = 0.002 Identities = 55/234 (23%), Positives = 86/234 (36%), Gaps = 38/234 (16%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E PEF+ KD I +G + + G + WLKDG + + + Sbjct: 915 VNEKHFAPEFED-WKDTIDALDGQDVNISTWVR--GKPKPEIVWLKDGEELRNTMHVQIK 971 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021 L + V+ DAG YTCRA N G + +T+ E +Q Sbjct: 972 CYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITV----------------EALQ 1015 Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081 D + + E ++IT+ F S + R +P+ V+W+ Sbjct: 1016 KKGDTPTFMSKL-EPIEITEGDDF------------QLSCNVTGRPQPE------VQWFR 1056 Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 + I + R + +D AL + +D GVY V N G A +TV Sbjct: 1057 DEVLIKPSRRFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV 1110 Score = 44.8 bits (101), Expect = 0.002 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 2/99 (2%) Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD 1366 VM AP+ + L + EG + L C++ + T+ EW N + + RF+ ++ Sbjct: 1311 VMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQ 1368 Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 L + +V D+ Y N GE +S L+VI K Sbjct: 1369 TGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK 1407 Score = 44.8 bits (101), Expect = 0.002 Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 5/102 (4%) Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028 +D + + E+ QF +P+ E+ PV + + PT V W+ NG+ ++ G + Sbjct: 1503 RDYAPIFEEKQFLEPL---EIQVRQPVEVSYHVRGRPKPT--VTWWKNGKELRDGKHVEI 1557 Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 Y L IL + ED G+Y C A N VG A V+V+ Sbjct: 1558 RSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVE 1599 Score = 44.8 bits (101), Expect = 0.002 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 2/97 (2%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 +AP FT +K I V E + F R+ +P V W RN I R T D Sbjct: 1901 EAPSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETY 1958 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 L ++ + +D+G Y C A N +G+A ++ + V + Sbjct: 1959 KLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995 Score = 44.8 bits (101), Expect = 0.002 Identities = 91/388 (23%), Positives = 136/388 (35%), Gaps = 58/388 (14%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P ++ D+ K EG+ A F+ + P VEWF + G RY+ + Sbjct: 3031 PLITHKLHDM-KAYEGKEARFDIEVT--GHPSPTVEWFKGPSGISEGRRYQLMSN----- 3082 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401 E G++ + ++ D KC + +NL G + + Sbjct: 3083 --------EEQGKHSLIVSDLNADDD--GIYKCVA-QNL-----------AGKASTRAML 3120 Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461 D + R +EE+ PV + EGE A + ++ P VEW+ +GK Sbjct: 3121 DVIARDFGPEFDEEESPKPVI---------VNEGEEA--QMMVSVRGRPKAVVEWFKDGK 3169 Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ-----GKR 3516 L R L I PED G Y C A + G + T + V+ K Sbjct: 3170 FLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRTFDLSVKVPKPKDKW 3229 Query: 3517 NIILESQLPKGMEGTI-DKIAALEGYSG----TVDTLTPEAESGNPPEFTTTPSDLI--L 3569 ++ S + +E +K + SG TV+ + + F T + L Sbjct: 3230 SLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCML 3289 Query: 3570 SENSSAHFEC---RLIPVNDSSMR--VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQ 3624 + FEC RL R VEWF L G R + L I ++ Sbjct: 3290 VFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHM 3349 Query: 3625 RDAGLYTCKATNRHGEATVSCKLQVKGR 3652 D G Y ATN HG L VK R Sbjct: 3350 EDTGPYKIIATNEHGSTGSVVDLTVKER 3377 Score = 44.8 bits (101), Expect = 0.002 Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 20/216 (9%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 VEW KDG+ + S R+ L I VT D G Y C A + G+++ + +L++ Sbjct: 3162 VEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRTFDLSVK 3221 Query: 1003 TKK-----DIIAESQHPGGLE-----KIQYLEDASRYSKRTEEEVK----ITQKPRFLGP 1048 K + A S LE K +++ + S T E K I + RF Sbjct: 3222 VPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTY 3281 Query: 1049 LKG-TNKIVEGQSAHFE---ARVEPQ--SDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 G +V ++ FE AR+E TVEW+ ++ R + Sbjct: 3282 FDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYT 3341 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 L I+++ ED+G Y ++A N G +TV+ R Sbjct: 3342 LVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKER 3377 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 2/97 (2%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P F + VTEG A ++ V P ++WY + P+ HR +T +D V L Sbjct: 3982 PIFVTELSPLSVTEGDYTKFVAHVSGV--PLPSIQWYKDDNPISSNHRIRTFFDGHVVKL 4039 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074 I ED G Y N G A +++ + V + G Sbjct: 4040 LIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYG 4076 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Query: 4105 SKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG- 4163 S R P FV VT G A F RV G P+P+++W + ++N R+ ++ +G Sbjct: 4545 SHCRMKPTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISEEGD 4604 Query: 4164 MYHFDIPKTRQYDTG 4178 +Y+ I + D+G Sbjct: 4605 LYNLTIENVGRDDSG 4619 Score = 44.8 bits (101), Expect = 0.002 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 3/87 (3%) Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432 R +P F + L+ + + G+ A F R+ G P K+ W+++ + + R + + Sbjct: 4548 RMKPTFVERLREVTTVFGGE-ASFSVRV--KGFPRPKIVWYKDITRLINRGRFHISEEGD 4604 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459 ++TI +V +D G YMC SN +G+ Sbjct: 4605 LYNLTIENVGRDDSGTYMCILSNAVGK 4631 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 3/90 (3%) Query: 2501 PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTT 2560 P+ ++ P F LT P+ + EG+ E + G P + EW+ N +K R+ Sbjct: 4746 PEEDWSAPSFVIELT-PTTVTEGESTALEVEIT--GTPLPKVEWFKNDKPVKHDHLVRSY 4802 Query: 2561 HDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 D + L + DAGLY C +N G Sbjct: 4803 FDGKVIRLIVRRTTLEDAGLYRCTILNDLG 4832 Score = 44.8 bits (101), Expect = 0.002 Identities = 47/196 (23%), Positives = 78/196 (39%), Gaps = 29/196 (14%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 V WY +G ++ R+ T L+I S+ +ED+G Y AR+ G+ S + Sbjct: 4978 VIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCIL--- 5034 Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196 D ++ P +++ KPV + + + EG NI Sbjct: 5035 -----DVQAV------------------PKEEVDHGQIVKPVITRKIRDAQG-EEGSNIR 5070 Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256 E ++ P VEW+ + G +++ G +L I DTG Y V A N Sbjct: 5071 FEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATN 5128 Query: 1257 HLGSAHTSAIVRVIER 1272 GS+ + A V V ++ Sbjct: 5129 QAGSSTSRAEVVVKDK 5144 Score = 44.4 bits (100), Expect = 0.002 Identities = 22/96 (22%), Positives = 43/96 (44%), Gaps = 2/96 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P + + A++G + G+P ++EW K+G+ ++A+ R F I+L Sbjct: 730 PTITTEMTDIQAIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMIAL 787 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732 + ++D G Y C + G + A + V R+ Sbjct: 788 SFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS 823 Score = 44.4 bits (100), Expect = 0.002 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 2/69 (2%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVT--LSINSLRNDDSGIYTCKATNLLGEAVST 2729 P +IEW+ +T G R K D + L I+ ++ DD+G C ATN G+ V Sbjct: 1144 PKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVR 1203 Query: 2730 ASIKIEDRH 2738 A +++E+++ Sbjct: 1204 ADLEVEEKN 1212 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 6/113 (5%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 PE + ++ + + EG ++ + TL EWLK+ + + R T F+ Sbjct: 1315 PEIRQQLQAE-DVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGT 1371 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV---TKKDIIAESQHPGGLE 1018 LTI++VT+ DA Y N G+ ++SA L ++ TK +++ + + G+E Sbjct: 1372 LTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDVKGVE 1424 Score = 44.4 bits (100), Expect = 0.002 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 P + E++ K+ + +G A F KL G P+P + W + + +Y ++Q S Sbjct: 1411 PEVLEKM-KDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQ--KYS 1467 Query: 131 LLIKQIGPGDEGEYTCTARNQYGE 154 L IK + D G Y C A N+ G+ Sbjct: 1468 LTIKDLNLQDIGTYKCIASNEAGK 1491 Score = 44.4 bits (100), Expect = 0.002 Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 3/104 (2%) Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 + + + P F L+ + ++ EG N F ++ +P+ V WY++ I R + Sbjct: 1895 VPKARDEAPSFTTTLKPI-DVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRT 1951 Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 F+ L + ++ +DAG Y A N +G+A TA + V R Sbjct: 1952 TFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995 Score = 44.4 bits (100), Expect = 0.002 Identities = 28/116 (24%), Positives = 60/116 (51%), Gaps = 7/116 (6%) Query: 753 YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLT-PVSD-PTMRVEWYKDG 810 Y ++ + + + P F L+ + ++E F+++L VS P +++W K+G Sbjct: 2918 YRSFEVDVTAPKVKGEAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNG 2972 Query: 811 RPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866 +P+ + R+ + ++ L+I + +DAG+Y A N G S+A++ V+ R+ Sbjct: 2973 KPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRRN 3028 Score = 44.4 bits (100), Expect = 0.002 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 4/97 (4%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYV 1368 P + LH+++ EG + ++ G + VEWF I G R++ E Sbjct: 3031 PLITHKLHDMKAYEGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKH 3088 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 +L + + +D G+Y C A N G+A T L VIA+ Sbjct: 3089 SLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIAR 3125 Score = 44.4 bits (100), Expect = 0.002 Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 4/116 (3%) Query: 1160 SKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS 1219 SK + + + S+ P F+ L N V EG + L C++ G P VEWF + + Sbjct: 3670 SKTFDVKAGVPDGSRVTPKFLSHL-NSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQL 3726 Query: 1220 VTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275 +T R ++ L D G Y A N GS +SA++ V+ R+ I Sbjct: 3727 ITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVI-VVNRASI 3781 Score = 44.4 bits (100), Expect = 0.002 Identities = 57/223 (25%), Positives = 89/223 (39%), Gaps = 45/223 (20%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLND-FG 3751 PR + +D +D +G F RVE G P ++ WFH + R + + D + Sbjct: 3783 PRIIEKPRD-VDAVDGTDAKFTVRVE--GFPQPKVTWFHESTKIVSRGRYEISRVGDLYS 3839 Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811 + ++Y++ G Y C ATN G K+T D+ + P ++G Sbjct: 3840 LVIRGVEYLHV---GTYKCIATNDAG------KVTAHCHLDVTKQDFAPI-VAG------ 3883 Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871 S+ P EPIV V E V V K P +EW+++G+L Sbjct: 3884 -----SEMP--EPIV--------------VREGCEVSMMANVRGKPAPT--VEWFKDGQL 3920 Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDF 3914 L + + + +LD+L DSG Y A ND G + Sbjct: 3921 LSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAY 3963 Score = 44.4 bits (100), Expect = 0.002 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 3/100 (3%) Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746 + +E + P F +E+ V EG + VE G P +++WF N +P V + Sbjct: 4745 VPEEDWSAPSFVIELTPTT-VTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRS 4801 Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786 D I L + DAG Y C N G+A++ A ++ Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLS 4841 Score = 44.4 bits (100), Expect = 0.002 Identities = 56/224 (25%), Positives = 91/224 (40%), Gaps = 43/224 (19%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P T +I+D EG + F+ V+ P ++W+ A G + G + Sbjct: 5052 PVITRKIRD-AQGEEGSNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYS 5108 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814 L I + D G Y ATN+ GS+T+ A++ +V + L Sbjct: 5109 LTITGVQKDDTGSYKVVATNQAGSSTSRAEV-------VVKDKPL--------------- 5146 Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG-KLLP 3873 APK + +T P IT+ G + V + PK + WY++G K+L Sbjct: 5147 ----APKVAEMTATGPITITR----------GNQLNLNVTIRGKPKPSVVWYKDGNKILT 5192 Query: 3874 SGH-RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTK 3916 S + + R+ D+ L IL+ +E +G Y C A + G K Sbjct: 5193 SRNVQIRSCGDV--YHLIILFTKSEHAGTYSCEATSKLGNTSAK 5234 Score = 44.4 bits (100), Expect = 0.002 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 3/96 (3%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP FT L+ D ++EG ++ P +EW+++ +T RL++ D +V Sbjct: 5543 APAFTAPLQHID-ILEGDTTRFIGEITGVPVP--VVEWYRDDRPVTRDHRLRTYSDGRVV 5599 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 L + D+G++ C N LG S+AS+ + + Sbjct: 5600 ILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNE 5635 Score = 44.4 bits (100), Expect = 0.002 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR-TVYDMGFVS 3888 P+ ++K E RF+ V P R++WYR + +RY T+ G S Sbjct: 5640 PEINEKLKKIEAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMAS 5697 Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912 L I + ED G Y C AVN++GE Sbjct: 5698 LTIRKIRQEDGGLYGCVAVNEYGE 5721 Score = 44.0 bits (99), Expect = 0.003 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845 +EG+ F C V P I W+ + +P+ + R K + D + +L I ++D G Sbjct: 197 QEGEQYKFTCAVTGKPKPV--ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGT 254 Query: 2846 YTCKATNSKGSATTSGSLRCT 2866 Y + TN GS +++ L T Sbjct: 255 YKVEITNDLGSISSTADLEVT 275 Score = 44.0 bits (99), Expect = 0.003 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 5/112 (4%) Query: 1293 DAARRTKQVREDIT--VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350 DA + T + D+ V+Q P+F + + IE G ++ G +V W+ + Sbjct: 612 DAGKTTALLNLDVNEKVVQ-PEFDKEVKPIEVKHGEEATTSLEIK--GKPKPKVTWYKDL 668 Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 P+ + D L++++ P+D G Y C+ATN+ G A S ++V Sbjct: 669 VPLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKV 720 Score = 44.0 bits (99), Expect = 0.003 Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 2/98 (2%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G P TT +D+ + C + + + VEWF +GKPL R+ + Sbjct: 727 GETPTITTEMTDIQAIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERM 784 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 + L + D G Y C +N G + + +++V+ R Sbjct: 785 IALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822 Score = 44.0 bits (99), Expect = 0.003 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 5/100 (5%) Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250 +G++ L C + G+P VEWF +G+ + R ++ +AL D G Y Sbjct: 743 DGEDCKLICHVT--GEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRY 800 Query: 1251 TVRAVNHLGSAHTSAIVRVIERS---DIVTDTQNEQAIEQ 1287 N GS ++A V+V +RS +++T ++ +E+ Sbjct: 801 KCVISNVFGSVSSAAEVKVEDRSLKPEVITSMRDCDCVEE 840 Score = 44.0 bits (99), Expect = 0.003 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823 E S +P+ I ++D ++E A F + + +P +EW+ PI R Sbjct: 820 EDRSLKPEVITSMRDCDCVEE-ETASFHCEFSGKPEP--EIEWFCGPNPIVPGGRFHVTE 876 Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 SL I L+ EDAG+Y A N G+ + A ++V Sbjct: 877 EGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKV 915 Score = 44.0 bits (99), Expect = 0.003 Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 5/118 (4%) Query: 2222 QLEAQGHSTRIEVEEPKIS--PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279 ++ A S ++V PK+ P F ELR + E + C V P +I++ Sbjct: 2913 RIGAAYRSFEVDVTAPKVKGEAPSFSLELRPIAAI-EEFDSKLICHVSG--KPKPQIKWT 2969 Query: 2280 HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 NGK ++S R +D L I +DAG Y A NA G +S+ ++TV+ + Sbjct: 2970 KNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027 Score = 44.0 bits (99), Expect = 0.003 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 5/96 (5%) Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028 K + P F +++ ++ E ++ K C ++ G P +++W NGKP+ R YD Sbjct: 2931 KGEAPSFSLELRPIAAIEEFDS-KLICHVS--GKPKPQIKWTKNGKPVESDGRLRTDYD- 2986 Query: 4029 GYVAMNFGW-VYPEDSGEYLCRATNLYGMDETKAVI 4063 G VA W V +D+G Y C A+N G + A + Sbjct: 2987 GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAAL 3022 Score = 44.0 bits (99), Expect = 0.003 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 33/191 (17%) Query: 2404 GDPTLKVEWFRNEKLIEDSSR--ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXX 2461 G+P V W+R+ L+ D++R I D YV+ I + ED G Y+C A + +G Sbjct: 3408 GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVN--IYGLTLEDAGNYVCEARSRIG--- 3462 Query: 2462 XXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELW 2521 LE K+ + P E++ K + Q + Sbjct: 3463 -------TAIRSCTLEI-------KVPSMGGPEEKK-------ISKALIGQG-DNDVQAV 3500 Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT--THDFGFVTLDINSVVANDAG 2579 EG ++ R+ G P EWY ++L +++ T + G +L +N V +D G Sbjct: 3501 EGWKVQFQTRIT--GYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIG 3558 Query: 2580 LYMCKAINRAG 2590 Y C A N AG Sbjct: 3559 TYKCLATNSAG 3569 Score = 44.0 bits (99), Expect = 0.003 Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 11/111 (9%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRY---RTFHDFG 3338 P+ I + +DV V+G A F R+ P KV WF+ K+ RY R + Sbjct: 3783 PRIIEKPRDVDA-VDGTDAKFTVRVEGFPQP--KVTWFHESTKIVSRGRYEISRVGDLYS 3839 Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE--NLILDSQLP 3387 +VI + Y + G Y+C+ATN G+ + +L T ++ ++ S++P Sbjct: 3840 LVIRGVEYLHV---GTYKCIATNDAGKVTAHCHLDVTKQDFAPIVAGSEMP 3887 Score = 44.0 bits (99), Expect = 0.003 Identities = 27/57 (47%), Positives = 29/57 (50%), Gaps = 2/57 (3%) Query: 4124 EGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK--LTYDGMYHFDIPKTRQYDTG 4178 EG ARF VTG P PRV W I + +RY LT DGM I K RQ D G Sbjct: 5653 EGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGG 5709 Score = 43.6 bits (98), Expect = 0.004 Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 8/115 (6%) Query: 3840 TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAED 3898 TVE E RF+ +E PK +EWY+ + S +++ + D G SL I + +D Sbjct: 2 TVESGEA-RFDVTIEGY--PKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDD 58 Query: 3899 SGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPRGMKRSEALTQMEATI 3950 +G Y C A ND G+ + +S K+ P I + Q P + E++ ++ TI Sbjct: 59 AGAYKCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGESV-NLDLTI 112 Score = 43.6 bits (98), Expect = 0.004 Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 5/116 (4%) Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233 K K V P V EG+ C + G P + W+ +G+ + R K +D Sbjct: 181 KGKAPTVTSELKPDKVQEGEQYKFTCAVT--GKPKPVISWYKDGQPIKADRRVKDSFDGT 238 Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI---ERSDIVTDTQNEQAIE 1286 L I D G Y V N LGS ++A + V + ++V +N +++E Sbjct: 239 TSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVE 294 Score = 43.6 bits (98), Expect = 0.004 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P F + + + I I EG F+ G V+W +D ++ S R ++ A Sbjct: 1021 PTFMSKL-EPIEITEGD--DFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 1077 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 LT+K + D G Y C N G ++ A++T++ K Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113 Score = 43.6 bits (98), Expect = 0.004 Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 3/97 (3%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 V AP L++ D + EG L +V +P L EW KN L+ R K+ FD Sbjct: 1311 VMIAPEIRQQLQAED-VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDG 1367 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 TL+I ++ D+ Y N GE S+A +K+ Sbjct: 1368 QTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKV 1404 Score = 43.6 bits (98), Expect = 0.004 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698 ++AP T+ L+S ++ E L V+ DP+ EW K+ + L S+FD Sbjct: 1605 EEAPKLTSQLRSA-RITESDDFELACDVKGTPDPSY--EWLKDDKPVKFDRHLSSSFDGK 1661 Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 TL+ ++ D G YT N G S+A++ I Sbjct: 1662 KCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDI 1697 Score = 43.6 bits (98), Expect = 0.004 Identities = 22/73 (30%), Positives = 34/73 (46%) Query: 790 FEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVN 849 FE P EW KD +P+ ++S F+ +LN ++ D GSYTV N Sbjct: 1625 FELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKN 1684 Query: 850 KLGEAISTASIRV 862 G S+A++ + Sbjct: 1685 AHGSTYSSANLDI 1697 Score = 43.6 bits (98), Expect = 0.004 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566 KP+ +V + E+ EG A E +V V P++ EWY + G RF+ T + + Sbjct: 1998 KPVIKEV-SKTFEVSEGGTASIEVKVSGVPVPTV--EWYHGSNRVLDGDRFQVTQEGDYH 2054 Query: 2567 TLDINSVVANDAGLYMCKAINRAG 2590 TL I V A Y C A N AG Sbjct: 2055 TLSIRDVGDQAAASYKCVAFNNAG 2078 Score = 43.6 bits (98), Expect = 0.004 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 4/97 (4%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS--RVKTINDFGFV 3615 PE P+ L++ E + + F+ R+ + VEWF+ + L G R+++ + G Sbjct: 2529 PEIIEKPAGLVIVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLY 2586 Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 L + V G Y A+N HG+A L V R Sbjct: 2587 SLVVSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER 2623 Score = 43.6 bits (98), Expect = 0.004 Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 2/91 (2%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G PT I W K+G+ ++ + R R L +L+L +D+G YTC A + G A Sbjct: 2861 GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920 Query: 724 AVLHVT-PRATIERTSQHPETLQYIQQLEDY 753 + VT P+ E S E L+ I +E++ Sbjct: 2921 FEVDVTAPKVKGEAPSFSLE-LRPIAAIEEF 2950 Score = 43.6 bits (98), Expect = 0.004 Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 7/90 (7%) Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLI--PVGDPTLKVEWFRNEKLIEDSSRITKT 2428 V + P F+ L+ I I+E FD +LI G P +++W +N K +E R+ Sbjct: 2930 VKGEAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTD 2984 Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 +D ++I V +D G Y C ASN G Sbjct: 2985 YDGIVAYLSIWQVSHDDAGTYECIASNAAG 3014 Score = 43.6 bits (98), Expect = 0.004 Identities = 77/306 (25%), Positives = 119/306 (38%), Gaps = 27/306 (8%) Query: 3502 GEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA-LEGYSGTVDTLTPEAESGNPP-E 3559 G S + QGK ++I+ S L +G +A L G + T L A P + Sbjct: 3074 GRRYQLMSNEEQGKHSLIV-SDLNADDDGIYKCVAQNLAGKASTRAMLDVIARDFGPEFD 3132 Query: 3560 FTTTPSDLILSENSSAHFECRLIPVNDSSMRV-EWFHNGKPLLTGSRVKTINDFGFVILE 3618 +P +I++E A ++ V V EWF +GK L R+ + L Sbjct: 3133 EEESPKPVIVNEGEEAQM---MVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLV 3189 Query: 3619 IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEET 3678 I V D G Y C A++ +G ++ + L VK + + LP+ F S ++ LE Sbjct: 3190 IYHVTPEDEGSYKCVASSTNGRSSRTFDLSVKVPKPKD-KWSLPA-FSSKLRPLETLEGE 3247 Query: 3679 LHK------REEI-TIE---DEKP--NPPRFTVEIKDNIDVPEGGPV-HFDC---RVEP- 3721 K E I T+E D+ P + RF + + F+C R+E Sbjct: 3248 KTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAH 3307 Query: 3722 -VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780 G P ++WF G R L I ++ D G Y ATN+ GS Sbjct: 3308 VAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTG 3367 Query: 3781 TTAKIT 3786 + +T Sbjct: 3368 SVVDLT 3373 Score = 43.6 bits (98), Expect = 0.004 Identities = 55/220 (25%), Positives = 90/220 (40%), Gaps = 35/220 (15%) Query: 922 KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981 K GGF + L+ G+ V W +DG + ++R+ + I +T+ DAG+ Sbjct: 3395 KAGGFVNISFTLK--GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGN 3452 Query: 982 YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041 Y C A + IG A S L I + GG EE KI++ Sbjct: 3453 YVCEARSRIGTAIRSCTLEI--------KVPSMGG-----------------PEEKKISK 3487 Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR---IQTYHDF 1098 +G + VEG F+ R+ VEWY ++ +++ QT D Sbjct: 3488 --ALIGQGDNDVQAVEGWKVQFQTRITGYP--YPHVEWYRGTIKLHDSDKYKIAQTKED- 3542 Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 G +L + V +D G Y +A N+AG + ++ V+ + Sbjct: 3543 GLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDVKDK 3582 Score = 43.6 bits (98), Expect = 0.004 Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 3/97 (3%) Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297 K S P FVTEL + V EG F V V P+ I++Y + + S R FD Sbjct: 3978 KWSSPIFVTELSPLS-VTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFFDG 4034 Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 V L I ED G+Y V N G TS+ ++V Sbjct: 4035 HVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071 Score = 43.6 bits (98), Expect = 0.004 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 1/90 (1%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169 P+FV+ ++V EG++ +F V+G P P + W + N I + R + +DG + I Sbjct: 3982 PIFVTELSPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLI 4041 Query: 4170 PKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199 + D G+ +V+ L V Sbjct: 4042 GQITLEDQGQYKVVLKNESGSATSSAKLSV 4071 Score = 43.6 bits (98), Expect = 0.004 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 4/88 (4%) Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTS--IFRFGYISLDMLS 700 + +VTA+EG K+ +TR+ G P +EW + + I R+ + + G SL + Sbjct: 4263 MANVTAVEGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISD 4320 Query: 701 LNIQDSGEYTCRAVSATGVAETKAVLHV 728 + ++DSG Y A + G A T A L V Sbjct: 4321 VQLEDSGSYRAVASNNLGEATTLAELTV 4348 Score = 43.6 bits (98), Expect = 0.004 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 3/102 (2%) Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ 1093 E+ K P F L+ + + E +SA F R E ++W+ N + ++ +RI Sbjct: 4446 EDVCKSALAPGFKSALRSLD-VTEDESAEF--RCEVSGSPAPRIQWFMNDQPVSRDSRII 4502 Query: 1094 TYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 T D L I +D+GVY +A N G A +A + V Sbjct: 4503 TSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544 Score = 43.6 bits (98), Expect = 0.004 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Query: 2932 EGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNK 2991 E + E P +I+W+ N + + + SR +SD L + +D+G+Y C A N Sbjct: 4473 EFRCEVSGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVND 4532 Query: 2992 RGEAFTSSTV---YCTSKDNLIER 3012 G A +++ + +C K +ER Sbjct: 4533 NGSATSTADLNVSHCRMKPTFVER 4556 Score = 43.6 bits (98), Expect = 0.004 Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 4/137 (2%) Query: 1805 KASLQLESQHESALQKIQQLEDSSRYQRREDVEVA-VNQAPRFITQLNGPTKLSEGQSAH 1863 K ++ + ++ + K + D+ D+ V+ P F+ +L T + G+ A Sbjct: 4511 KLAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGE-AS 4569 Query: 1864 YECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923 + R++ +P P ++ WY + L + R+ S + L I V +DSG Y C N Sbjct: 4570 FSVRVKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSN 4627 Query: 1924 NLGQAVSSIRLNVQSKE 1940 +G+ +L V+++E Sbjct: 4628 AVGKETCRSQLVVEAEE 4644 Score = 43.6 bits (98), Expect = 0.004 Identities = 25/75 (33%), Positives = 38/75 (50%) Query: 799 DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858 +P V WYKDG ++ ++R+ + LNI L +EDAG+Y A +KLG+ + Sbjct: 4973 NPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSC 5032 Query: 859 SIRVAARSTVTADLG 873 + V A D G Sbjct: 5033 ILDVQAVPKEEVDHG 5047 Score = 43.2 bits (97), Expect = 0.005 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 3/88 (3%) Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430 V + P T L+ D +QEG+ F C + G P + W+++ + I+ R+ + D Sbjct: 180 VKGKAPTVTSELKP-DKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFD 236 Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458 ++ I V+ +D+G Y +N LG Sbjct: 237 GTTSTLLIKDVKQDDKGTYKVEITNDLG 264 Score = 43.2 bits (97), Expect = 0.005 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 2/97 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 +AP + L + EG C + G + W+ +G+PIK R + +++ Sbjct: 183 KAPTVTSELKPDKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFDGTTS 240 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 L + V +D G Y + TN LG ++ L V K Sbjct: 241 TLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPK 277 Score = 43.2 bits (97), Expect = 0.005 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 2/95 (2%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637 P TS+++ + E + A F + ++EW+ P+ G RF T +L Sbjct: 826 PEVITSMRDCDCVEEETASFHCEFSGKPEP--EIEWFCGPNPIVPGGRFHVTEEGNIQSL 883 Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672 I ED+G Y C A NA G+ T V+ K Sbjct: 884 AISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 43.2 bits (97), Expect = 0.005 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 2/87 (2%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712 K VEG ++ P+ IEW+ + G R K + D +L+I L D Sbjct: 1421 KGVEGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDI 1478 Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHW 2739 G Y C A+N G+ A +++++R + Sbjct: 1479 GTYKCIASNEAGKVTQRAELEVKERDY 1505 Score = 43.2 bits (97), Expect = 0.005 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 5/102 (4%) Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR--TSND 1898 N P IT K EG+ A ++ + +P P VEW+ + G RY+ ++ + Sbjct: 3028 NMRP-LITHKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEE 3084 Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 G +L + + +D G Y C A N G+A + L+V +++ Sbjct: 3085 QGKHSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIARD 3126 Score = 43.2 bits (97), Expect = 0.005 Identities = 73/354 (20%), Positives = 136/354 (38%), Gaps = 26/354 (7%) Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI--HDFGYVALDIIDLIAEDSG 1515 EG+ F+ +E + VEWFK ++ G R++ + + G +L + DL A+D G Sbjct: 3044 EGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDG 3101 Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTT 1575 IY C A NL G + + R+ D++ + G E + E+ K + +E Sbjct: 3102 IYKCVAQNLAG------KASTRAMLDVI---ARDFGPEFDE--EESPKPVIVNEGEEAQM 3150 Query: 1576 QAPICTTSLKNVE-IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSR---FTETNN 1631 + VE K+G+ + RR+ S ++ P GS + TN Sbjct: 3151 MVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNG 3210 Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691 D+ +P+ ++ A + + + + +K+ ++ + +P + Sbjct: 3211 RSSRTFDLSVKVPKPKDKWSLPAFS----SKLRPLETLEGEKTKFVVNVSGEPIPTVEWF 3266 Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751 +D + +H + V + + E A EA + G P+ VEW Sbjct: 3267 KDDTPI-KHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAHV--AGVPRPTVEWFLGSA 3323 Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + R L + ++ ED+G Y A NE G + L V+ + Sbjct: 3324 KLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKER 3377 Score = 43.2 bits (97), Expect = 0.005 Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 2639 QQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 Q AP H + V EGQ + ++ ++ + P L++ W+K+G L R+ Sbjct: 3583 QYAPEIPGHEDRQELNVPEGQEINMDVVIKSK--PRLEVSWYKDGELLQDTKRIDIRSRG 3640 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733 L I S +DSG+Y C+ + LG + T +K Sbjct: 3641 DHYYLVIPSAAPEDSGLYKCEGVSTLGTSSKTFDVK 3676 Score = 43.2 bits (97), Expect = 0.005 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 IV +EG + NV PT +EWF + + L + Y +LD+ T + D Sbjct: 3890 IVVREGCEVSMMANVRGKPAPT--VEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQAD 3947 Query: 2843 SGIYTCKATNSKGSATTSGSLRCT 2866 SG Y ATN GSA +L T Sbjct: 3948 SGTYKFVATNDLGSAYRIFNLNVT 3971 Score = 43.2 bits (97), Expect = 0.005 Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 9/137 (6%) Query: 1407 DLILESQHPSGLEKIQYLEDT-SRYK-----KTDIIDESVTIKPRFVTRPKSIENVIEGQ 1460 DL+ +Q SG K D S Y+ T I + P FVT + +V EG Sbjct: 3939 DLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTELSPL-SVTEGD 3997 Query: 1461 HVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCR 1520 + F + V + ++W+K+ P++ HR R D V L I + ED G Y Sbjct: 3998 YTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVV 4055 Query: 1521 AVNLVGTDEVSCRLTCR 1537 N G+ S +L+ R Sbjct: 4056 LKNESGSATSSAKLSVR 4072 Score = 43.2 bits (97), Expect = 0.005 Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 6/107 (5%) Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027 +K P FVT++ S S+ E + TKF ++ G P ++W+ + P+ +R +D Sbjct: 3977 EKWSSPIFVTEL-SPLSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFD 4033 Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGI 4071 V + G + ED G+Y N G + A V + GKP I Sbjct: 4034 GHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAI 4080 Score = 43.2 bits (97), Expect = 0.005 Identities = 49/198 (24%), Positives = 79/198 (39%), Gaps = 32/198 (16%) Query: 1477 KVEWFKNGQPVTIGHRF--RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 +V W+K+G ++ R R D Y L+I L +ED+G Y C A + +G SC L Sbjct: 4977 EVIWYKDGTLLSDTTRMDTRSRGDTHY--LNIFSLTSEDAGTYMCEARSKLGKCFRSCIL 5034 Query: 1535 TCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594 D+ + E VD P+ T +++ + +EG Sbjct: 5035 ------DVQAVPKEE--------------------VDHGQIVKPVITRKIRDAQGEEGSN 5068 Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654 FE + S VEWY + L G ++ + G +L I +D+G+Y A Sbjct: 5069 IRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVA 5126 Query: 1655 INALGEAVTSGIAIVHSK 1672 N G + + +V K Sbjct: 5127 TNQAGSSTSRAEVVVKDK 5144 Score = 43.2 bits (97), Expect = 0.005 Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 3/109 (2%) Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLR 2541 E K+ + + + P+ + P F + L P EG + +V G P Sbjct: 5223 EATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLL-PQNAREGDVVKFSCKVT--GYPEPE 5279 Query: 2542 FEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 EW +GV ++ R T +D TL I++ D+G+Y C N +G Sbjct: 5280 IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSG 5328 Score = 42.7 bits (96), Expect = 0.007 Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 7/141 (4%) Query: 1539 TTDIVRSTQNEAGLEQIQVLEDRSKYHRT-DM---VDEVTTQAPICTTSLKNVEIKEGQR 1594 T +I+ +T ++ G + + R+ D+ V E + P TT + +++ +G+ Sbjct: 687 TLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVKVAEPQGETPTITTEMTDIQAIDGED 746 Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654 + + +VEW+ + KPLK+ R + +AL ED G Y C Sbjct: 747 CKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVI 804 Query: 1655 INALGEAVTSGIAIVHSKKSI 1675 N G +V+S + +S+ Sbjct: 805 SNVFG-SVSSAAEVKVEDRSL 824 Score = 42.7 bits (96), Expect = 0.007 Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 11/152 (7%) Query: 992 QATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKG 1051 +A+ N++ +T K+ AE G + + S SK +K +P L + Sbjct: 1068 KASYDGNVSALTVKE--AELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPEVLQKMDD 1125 Query: 1052 TNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSANR--IQTYHDFGYVALDIAS 1107 + VEG A+F +++ P+ + +EWY +IT R I+T + L I Sbjct: 1126 V-RTVEGGKANFAVKIDAFPKPE----IEWYLGATKITDGGRFKIKTDKENCSYILFIDD 1180 Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139 V+ +D+G A NAAG+ + A + VE ++ Sbjct: 1181 VKLDDAGTVKCSATNAAGKTVVRADLEVEEKN 1212 Score = 42.7 bits (96), Expect = 0.007 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 4/109 (3%) Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892 + DV V + Q + EG A++ +I+ +P P +EWY + G R Sbjct: 1105 KADVTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPE--IEWYLGATKITDGGR 1162 Query: 1893 YRTSNDFGFAA--LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 ++ D + L I V +D+G C A N G+ V L V+ K Sbjct: 1163 FKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211 Score = 42.7 bits (96), Expect = 0.007 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 6/107 (5%) Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028 K++ P+ +Q++S + E + + C + G P+ EW + KP+ + +D Sbjct: 1604 KEEAPKLTSQLRS-ARITESDDFELACDVK--GTPDPSYEWLKDDKPVKFDRHLSSSFDG 1660 Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGIV 4072 +NF V D G Y N +G + A ++K+ KP I+ Sbjct: 1661 KKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSKPEIL 1707 Score = 42.7 bits (96), Expect = 0.007 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%) Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161 + +SK++ P + ++ DA +E G+ A+F ++ +PK V W I +G RY LT Sbjct: 1697 IVKSKSK-PEILETMKDAEGIETGK-AKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQ 1754 Query: 4162 ---DGMYHFDIPKTRQYDTGKIEVI 4183 DG Y I R D G +++ Sbjct: 1755 DEEDGTYSVTINDLRLEDCGTYKIV 1779 Score = 42.7 bits (96), Expect = 0.007 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 5/100 (5%) Query: 765 QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSI 822 ++ +P+ + ++D ++ G+ A F+ ++ P VEWY I R +T Sbjct: 1699 KSKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQD 1755 Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 G S+ I LR ED G+Y + A N +G+ A + V Sbjct: 1756 EEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV 1795 Score = 42.7 bits (96), Expect = 0.007 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 3/94 (3%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167 +PV + E + EG A E +V + P T++W+H ++ G R++ T + Y Sbjct: 1998 KPVIKEVSKTFE-VSEGGTASIEVKVSGVPVP--TVEWYHGSNRVLDGDRFQVTQEGDYH 2054 Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 L I + + +Y C A N G L + Sbjct: 2055 TLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVI 2088 Score = 42.7 bits (96), Expect = 0.007 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 1/48 (2%) Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453 K +KP + +KM + E +ARF+V F G P P + WYR + ++N Sbjct: 2284 KANKPKVI-EKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRN 2330 Score = 42.7 bits (96), Expect = 0.007 Identities = 60/237 (25%), Positives = 89/237 (37%), Gaps = 24/237 (10%) Query: 1057 EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVY 1116 EG+ A V + VEW+ +GK + + R+ L I V ED G Y Sbjct: 3144 EGEEAQMMVSVRGRPKAV--VEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSY 3201 Query: 1117 TVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIE-----ESKFV-----EPM 1166 VA + G + + ++V+ D S+ K R +E ++KFV EP+ Sbjct: 3202 KCVASSTNGRSSRTFDLSVKVPKPKDKWSLP-AFSSKLRPLETLEGEKTKFVVNVSGEPI 3260 Query: 1167 YQIEEISKSKPVFVQPL------SNPPPVSEGKNIHLEC---RLEP--MGDPTMRVEWFH 1215 +E P+ + + K EC RLE G P VEWF Sbjct: 3261 PTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFL 3320 Query: 1216 NGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 + G R++ L I + DTG Y + A N GS + + V ER Sbjct: 3321 GSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKER 3377 Score = 42.7 bits (96), Expect = 0.007 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 31/197 (15%) Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537 V WFK+G + R L+I L +D+G Y C A + +GT SC L Sbjct: 4184 VFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSCTLD-- 4241 Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHF 1597 V++ + G E +Q + + T+ + NV EG + Sbjct: 4242 -----VKAVRPRRGNE-VQACKPQ-------------------TSKMANVTAVEGWKVQL 4276 Query: 1598 ERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTCRAI 1655 + R+ VEW+ + + G R+ + G +L I EDSG+Y A Sbjct: 4277 DTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVAS 4334 Query: 1656 NALGEAVTSGIAIVHSK 1672 N LGEA T V K Sbjct: 4335 NNLGEATTLAELTVKGK 4351 Score = 42.7 bits (96), Expect = 0.007 Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 5/121 (4%) Query: 3933 VPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQ-PPRFVTQIQSQTSLVEMETT 3991 VP + + E T +K T+ L + + DV K P F + ++S + E E+ Sbjct: 4415 VPSASFEDSGIYKCETTSEKETTS-QLFDIHIEDVCKSALAPGFKSALRS-LDVTEDESA 4472 Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRAT 4051 +F C+++ G P +++WF N +P+ +R D + +D+G Y C A Sbjct: 4473 EFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAV 4530 Query: 4052 N 4052 N Sbjct: 4531 N 4531 Score = 42.7 bits (96), Expect = 0.007 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301 P FV LR T VF G+ A F +V+ P +I +Y + L + RFHI+ + + Sbjct: 4551 PTFVERLREVTTVFGGE-ASFSVRVKGF--PRPKIVWYKDITRLINRGRFHISEEGDLYN 4607 Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 L I++ +D+G Y NA+G T + V A+ Sbjct: 4608 LTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAE 4643 Score = 42.7 bits (96), Expect = 0.007 Identities = 50/204 (24%), Positives = 84/204 (41%), Gaps = 29/204 (14%) Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264 G+P V W+ +G ++ +R T L+I TS D G Y A + LG S Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031 Query: 1265 AIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVE 1324 I+ V QA+ + ++ D + K P +R + + + E Sbjct: 5032 CILDV-------------QAVPKEEV--DHGQIVK-----------PVITRKIRDAQGEE 5065 Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384 G+N+ E ++ VEW+ + G +++ + +L + V +D+G Y Sbjct: 5066 GSNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYK 5123 Query: 1385 CQATNQLGEAVTSCALRVIAKKDL 1408 ATNQ G + TS A V+ K L Sbjct: 5124 VVATNQAGSS-TSRAEVVVKDKPL 5146 Score = 42.7 bits (96), Expect = 0.007 Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 6/132 (4%) Query: 1007 IIAESQHPG--GLEKIQYLEDAS-RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF 1063 + +S+H G E L + S ++ + + + P FL L N EG F Sbjct: 5210 LFTKSEHAGTYSCEATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLLPQNAR-EGDVVKF 5268 Query: 1064 EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNA 1123 +V + +EW +G + S R+ T++D + L I + DSG+Y +N Sbjct: 5269 SCKVTGYPE--PEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNN 5326 Query: 1124 AGEAQLSASMTV 1135 +G A SA + V Sbjct: 5327 SGWASSSAELVV 5338 Score = 42.7 bits (96), Expect = 0.007 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 Q+ A P F+ EG+ +F C+VTG+P+P + W +G ++ + R Sbjct: 5238 QIQAPEAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGYPEPEIEWTRDGVSMESDERVTT 5297 Query: 4160 TYDGMYH-FDIPKTRQYDTG 4178 YDG + I D+G Sbjct: 5298 WYDGEHSTLSIHNANHADSG 5317 Score = 42.7 bits (96), Expect = 0.007 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 6/125 (4%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P F+ Q+ Q + E + KF C++ G P ++EW +G + R T YD + Sbjct: 5249 PAFLKQLLPQNAR-EGDVVKFSCKVT--GYPEPEIEWTRDGVSMESDERVTTWYDGEHST 5305 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA 4092 ++ DSG Y C N G + A + GK +L +MK + EA Sbjct: 5306 LSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK---TQRPRLSDNMKELFATVGGEA 5362 Query: 4093 SWQVT 4097 ++VT Sbjct: 5363 RFEVT 5367 Score = 42.3 bits (95), Expect = 0.009 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 5/121 (4%) Query: 3976 VTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNF 4035 VT + E E KF C A G P + W+ +G+P+ R +D + Sbjct: 187 VTSELKPDKVQEGEQYKFTC--AVTGKPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLI 244 Query: 4036 GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQ 4095 V +D G Y TN G + A ++ T KP ++ + M+++E + +A ++ Sbjct: 245 KDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPA---KPEVVRKMENVESVEGSDAFFE 301 Query: 4096 V 4096 V Sbjct: 302 V 302 Score = 42.3 bits (95), Expect = 0.009 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 29/229 (12%) Query: 659 RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718 R+ G+P ++ W K+G + + + L + + D G+Y C A + G Sbjct: 400 RLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLG 459 Query: 719 VAETKAVLHVTPRATIERTSQHPETLQYIQQ----------LEDYSKYQHQESIE----- 763 + + V P+ LQ ++ L+D +Y+ + + E Sbjct: 460 SPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVT 519 Query: 764 -------EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816 ++ +P+F+R ++D+ L E FE + P VEWY+ I Sbjct: 520 SLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQGYPRPI--VEWYRGTTRIKDG 576 Query: 817 SRIT---SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 R T S N Y SL I R ED+G Y A N G+ + ++ V Sbjct: 577 GRFTISESEENDMY-SLVIDEARTEDSGPYKCVASNDAGKTTALLNLDV 624 Score = 42.3 bits (95), Expect = 0.009 Identities = 54/209 (25%), Positives = 83/209 (39%), Gaps = 28/209 (13%) Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536 +V W+K+G + + + L I D G Y C A N +G+ + + ++T Sbjct: 410 EVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTV 469 Query: 1537 --RSTTDIVRS------TQNEAGLEQI--QVLEDRSKY--HRTDMVDEVTTQAPICTTSL 1584 + ++ S + E G + L+D +Y T+ V VT+ A I Sbjct: 470 VPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKA 529 Query: 1585 K----------NVEIKEGQRAHFERRLIPVSDATLK-VEWYHNNKPLKSGSRFT--ETNN 1631 K +V E ++ FE IP+ VEWY +K G RFT E+ Sbjct: 530 KVKPEFLRKVEDVTALETEQVWFE---IPIQGYPRPIVEWYRGTTRIKDGGRFTISESEE 586 Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGE 1660 +L I EDSG Y C A N G+ Sbjct: 587 NDMYSLVIDEARTEDSGPYKCVASNDAGK 615 Score = 42.3 bits (95), Expect = 0.009 Identities = 31/110 (28%), Positives = 44/110 (40%), Gaps = 9/110 (8%) Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755 K + S + EVIT M+D E + A F G P+ +EW PI Sbjct: 818 KVEDRSLKPEVITS-------MRDCDCVEEETASFHCEFS--GKPEPEIEWFCGPNPIVP 868 Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 R + +L + + ED+G Y C A N G+ T + L V K Sbjct: 869 GGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 42.3 bits (95), Expect = 0.009 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 3/88 (3%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G PK + WL++G + + + L + V+PED+G YTCRA N G Sbjct: 947 GKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKD 1006 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLE 1825 T+ V+ +LQ + + + K++ +E Sbjct: 1007 VTITVE---ALQKKGDTPTFMSKLEPIE 1031 Score = 42.3 bits (95), Expect = 0.009 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 11/134 (8%) Query: 1833 REDVEVAV-NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH 1891 R D+EV N AP F + G ++ EG+ A I P P+ V WY + V+ Sbjct: 1203 RADLEVEEKNVAPSFHGR-QGRLRVKEGREASVYFEISGKPKPS--VTWYKDDVVIGDED 1259 Query: 1892 R----YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947 R Y + + F I ED G Y C+A N++G A + ++V+ K+ ++ + Sbjct: 1260 RNVDIYSRGSSYYFT---IKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPE 1316 Query: 1948 HESALEKIQYLEDD 1961 L+ E D Sbjct: 1317 IRQQLQAEDVTEGD 1330 Score = 42.3 bits (95), Expect = 0.009 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 45/244 (18%) Query: 3684 EITIEDEKPNP--PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 E+ +E KP P+ T +++ + + E C V+ DP+ +W + +P Sbjct: 1595 EVQVEGVKPKEEAPKLTSQLR-SARITESDDFELACDVKGTPDPSY--EWLKDDKPVKFD 1651 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801 + + D L+ + D G YT N GS ++A + DIV P+ Sbjct: 1652 RHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANL------DIVKSKSKPE 1705 Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861 + E +K+ E I + KF +IK++ PK Sbjct: 1706 IL--ETMKD-----------AEGIETGKAKFDVKIKAY-------------------PKA 1733 Query: 3862 RIEWYRNGKLLPSGHRYRTVYDM--GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 +EWY + G RY D G S+ I + ED G Y A ND G+ +A + Sbjct: 1734 EVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAEL 1793 Query: 3920 SCKK 3923 + K+ Sbjct: 1794 TVKE 1797 Score = 42.3 bits (95), Expect = 0.009 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837 S L + E D+ C+V+ + DP+ EW ++KP+ S+ D +L+ Sbjct: 1612 SQLRSARITESDDFELACDVKGTPDPSY--EWLKDDKPVKFDRHLSSSFDGKKCTLNFKR 1669 Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKN 2870 D G YT N+ GS +S +L K+ Sbjct: 1670 VQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKS 1702 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 5/96 (5%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FG 2165 +P L + E ++ G +A F+ +++ P ++W+H +I G RY T D G Sbjct: 1703 KPEILETMKDAEGIETG-KAKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDEEDG 1759 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 ++ I ED GTY A N +G+ L V Sbjct: 1760 TYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV 1795 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 2/104 (1%) Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629 V + +AP TT+LK +++ EG+ F R+ + + V WY N + R T Sbjct: 1895 VPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTT 1952 Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673 + L + +D+G Y C A N +G+A + V+ ++ Sbjct: 1953 FDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKRE 1996 Score = 42.3 bits (95), Expect = 0.009 Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA--RLKSTFDFGLVTLSINSLRNDD 2711 +VEG + ++ R P ++EWF LT G R++S + GL +L ++ ++ D Sbjct: 2540 IVEGNDSRFDVRI--RGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597 Query: 2712 SGIYTCKATNLLGEAVSTASIKIEDR 2737 +G Y A+N G+A + + + +R Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTVNER 2623 Score = 42.3 bits (95), Expect = 0.009 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 3/67 (4%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVA-LDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668 +++W N KP++S R T+ G VA L I +D+GTY C A NA G V+S A+ Sbjct: 2965 QIKWTKNGKPVESDGRL-RTDYDGIVAYLSIWQVSHDDAGTYECIASNAAG-TVSSSAAL 3022 Query: 1669 VHSKKSI 1675 S++++ Sbjct: 3023 TVSRRNM 3029 Score = 42.3 bits (95), Expect = 0.009 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 +++W KNG+PV R R +D G VA L I + +D+G Y C A N GT S LT Sbjct: 2965 QIKWTKNGKPVESDGRLRTDYD-GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALT 3023 Score = 42.3 bits (95), Expect = 0.009 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 4/94 (4%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM--HDFGYV 1768 P+ T + D++ E + A F+ + G P VEW + I R M + G Sbjct: 3031 PLITHKLHDMKAYEGKEARFDIEV--TGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKH 3088 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 +L + +N +D G Y C A N G+A T + L V Sbjct: 3089 SLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDV 3122 Score = 42.3 bits (95), Expect = 0.009 Identities = 60/231 (25%), Positives = 91/231 (39%), Gaps = 34/231 (14%) Query: 3980 QSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG---YVAMNFG 4036 +S ++ E + + ++ G P VEWF +GK L+ +R + G Y+ + Sbjct: 3135 ESPKPVIVNEGEEAQMMVSVRGRPKAVVEWFKDGK-FLYDSRRMGVRSCGNSHYLVIYH- 3192 Query: 4037 WVYPEDSGEYLCRATNLYG-----MDETKAVIKTTGKPGI-VYDSQL-PKHMKSIEKIRE 4089 V PED G Y C A++ G D + V K K + + S+L P EK + Sbjct: 3193 -VTPEDEGSYKCVASSTNGRSSRTFDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKF 3251 Query: 4090 M---------EASWQVTPEQVVEESKAR-------CPPVFVSLPDAVTVEEGEWARFCCR 4133 + W + E + R C VF D+ E AR Sbjct: 3252 VVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKT-DSFECSE---ARLEAH 3307 Query: 4134 VTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTGKIEVI 4183 V G P+P V W L + +G RY+L D +Y I DTG ++I Sbjct: 3308 VAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKII 3358 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 3/98 (3%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F + + V E +A ++ G P+ VEW ++ I ++R+ + L Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMF--GKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTL 3744 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 + VN +D G Y C A N+ G + +SS + V ++AS+ Sbjct: 3745 IFETVNIQDRGAYRCTATNQEG-STSSSAVIVVNRASI 3781 Score = 42.3 bits (95), Expect = 0.009 Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 2/79 (2%) Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182 +G A F RVE P +T WFH KI + RY + +L I GTY Sbjct: 3796 DGTDAKFTVRVEGFPQPKVT--WFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTY 3853 Query: 2183 MCKATNKLGEAVNTCTLKV 2201 C ATN G+ C L V Sbjct: 3854 KCIATNDAGKVTAHCHLDV 3872 Score = 42.3 bits (95), Expect = 0.009 Identities = 22/77 (28%), Positives = 35/77 (45%) Query: 1186 PPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSA 1245 P P+ + + G P VEWF +G+ ++ + + LD++ T A Sbjct: 3887 PEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQA 3946 Query: 1246 DTGEYTVRAVNHLGSAH 1262 D+G Y A N LGSA+ Sbjct: 3947 DSGTYKFVATNDLGSAY 3963 Score = 42.3 bits (95), Expect = 0.009 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 7/132 (5%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P F+ L T + EG+S E VE VEW+ N K + + +++Y D + Sbjct: 4753 PSFVIELTPTT-VTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIR 4809 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE---TRSSIDTSSIHRGLYEKTR-HIE 1158 L + ED+G+Y N G A A ++V T+ + E T +E Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAVEGTEVRLE 4869 Query: 1159 ESKFVEPMYQIE 1170 KF PM ++E Sbjct: 4870 VIKFGCPMPKVE 4881 Score = 42.3 bits (95), Expect = 0.009 Identities = 36/117 (30%), Positives = 51/117 (43%), Gaps = 6/117 (5%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP F L + EG + + I P P VEWY + + + HR RT +D Sbjct: 5543 APAFTAPLQH-IDILEGDTTRFIGEITGVPVPV--VEWYRDDRPVTRDHRLRTYSDGRVV 5599 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959 L + D+G + C N+LG SS LNV E + +E L+KI+ E Sbjct: 5600 ILLLRQTNISDAGVFKCVLRNDLGTVASSASLNV--NEGYSKPEINEK-LKKIEAFE 5653 Score = 42.3 bits (95), Expect = 0.009 Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 3/91 (3%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P FT ++ +ID+ EG F + G P ++W+ + RP R+ T +D + Sbjct: 5544 PAFTAPLQ-HIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 L + DAG + C N G+ ++A + Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASL 5631 Score = 41.9 bits (94), Expect = 0.012 Identities = 55/246 (22%), Positives = 85/246 (34%), Gaps = 22/246 (8%) Query: 778 DLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRA 837 DL ++ + +LT +P V WYKDG + + ++ L+I Sbjct: 385 DLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKAST 444 Query: 838 EDAGSYTVRAVNKLGEAISTASIRVAARSTV-TADLGI-PEQRRYI-------------- 881 D G Y A N LG T + V + + G+ P Q R Sbjct: 445 NDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDA 504 Query: 882 -EKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDST 940 E V ++ KPEF ++D ++ E FE ++ G Sbjct: 505 GEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVED-VTALETEQVWFEIPIQ--GYPR 561 Query: 941 LRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSAN 998 VEW + ++ R T + +L I D+G Y C A N G+ T N Sbjct: 562 PIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLN 621 Query: 999 LTIVTK 1004 L + K Sbjct: 622 LDVNEK 627 Score = 41.9 bits (94), Expect = 0.012 Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 4/72 (5%) Query: 2666 VEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLL 2723 +E + P K+ W+K+ V L T +LKS D TL I + DD G Y C+ATN Sbjct: 652 LEIKGKPKPKVTWYKDLVPLLETRSIQLKSVGDEH--TLEIINATPDDEGKYKCEATNKA 709 Query: 2724 GEAVSTASIKIE 2735 G A + IK++ Sbjct: 710 GTAFRSFDIKVK 721 Score = 41.9 bits (94), Expect = 0.012 Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162 P V + D TVE G+ A F ++ PKP + W L I +G R+K+ D Sbjct: 1117 PEVLQKMDDVRTVEGGK-ANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTD 1168 Score = 41.9 bits (94), Expect = 0.012 Identities = 43/158 (27%), Positives = 61/158 (38%), Gaps = 12/158 (7%) Query: 3082 IEWFYNGKTIEASHR--IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139 IEW+ I R I+T +L I K D+GT C ATN G+ + LE Sbjct: 1148 IEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLE 1207 Query: 3140 CVDKSKGQKPRFTTHIQNIEGLKDGQ--SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR 3197 +K+ P F Q +K+G+ S +FE + P + WY + + R Sbjct: 1208 VEEKNVA--PSFHGR-QGRLRVKEGREASVYFEIS----GKPKPSVTWYKDDVVIGDEDR 1260 Query: 3198 -IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234 + S I + D G Y C A N G F Sbjct: 1261 NVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAF 1298 Score = 41.9 bits (94), Expect = 0.012 Identities = 35/140 (25%), Positives = 57/140 (40%), Gaps = 10/140 (7%) Query: 2119 ENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAED 2178 E++ EGD C+V +P T++W N + + R++T D L I D Sbjct: 1324 EDVTEGDDCRLTCKVSGYPEP--TLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLAD 1381 Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE-AQGHSTRIEVEEP 2237 + Y N GE ++ LKV I P LEK++ ++ +G V+ Sbjct: 1382 AVPYKVVVRNDAGEVSSSAKLKV------IRKCTKPEVLEKMKDVKGVEGDEATFNVKLS 1435 Query: 2238 KISPPRFVTELRGTTHVFEG 2257 P + GTT + +G Sbjct: 1436 GYPSPD-IEWYYGTTRIRDG 1454 Score = 41.9 bits (94), Expect = 0.012 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 2/91 (2%) Query: 2917 IAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDV 2976 ++ ++ EG +E V+ P +EWY + G RF++T + + TL + DV Sbjct: 2004 VSKTFEVSEGGTASIE--VKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDV 2061 Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007 ++ + Y C A+N G + + T ++ Sbjct: 2062 GDQAAASYKCVAFNNAGRTTYRADLVITERE 2092 Score = 41.9 bits (94), Expect = 0.012 Identities = 41/149 (27%), Positives = 62/149 (41%), Gaps = 16/149 (10%) Query: 2916 PIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVD 2975 PIAA + + H+ G+ +P+ I+W NGK +E R + D L + Sbjct: 2943 PIAAIEEFDSKLICHVSGKPKPQ------IKWTKNGKPVESDGRLRTDYDGIVAYLSIWQ 2996 Query: 2976 VYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKE 3035 V D+G Y C A N G +SS S+ N+ H K+ +++ KE Sbjct: 2997 VSHDDAGTYECIASNAAG-TVSSSAALTVSRRNMRPLITH--------KLHDMKAYEGKE 3047 Query: 3036 PGQQPDDDTGRPPEFTTVFKDIVDISEGQ 3064 + + TG P FK ISEG+ Sbjct: 3048 -ARFDIEVTGHPSPTVEWFKGPSGISEGR 3075 Score = 41.9 bits (94), Expect = 0.012 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 4/89 (4%) Query: 1719 DIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYVALNMKYVN 1776 D++ E F+ R+ G P VEW R + + S++ + + G +L + V Sbjct: 3496 DVQAVEGWKVQFQTRI--TGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVT 3553 Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 +D GTY C A N G + L V+ K Sbjct: 3554 KDDIGTYKCLATNSAGSSACRINLDVKDK 3582 Score = 41.9 bits (94), Expect = 0.012 Identities = 36/115 (31%), Positives = 46/115 (40%), Gaps = 5/115 (4%) Query: 1293 DAARRTKQVREDITVMQ-APQF--SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN 1349 DA + T D+T AP S I EG V + ++ G VEWF + Sbjct: 3860 DAGKVTAHCHLDVTKQDFAPIVAGSEMPEPIVVREGCEVSMMANVR--GKPAPTVEWFKD 3917 Query: 1350 GKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404 G+ + + +Y LDLL DSG Y ATN LG A L V A Sbjct: 3918 GQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTA 3972 Score = 41.9 bits (94), Expect = 0.012 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 + EG++ + + G P KVEWF+N+K ++ + D + + + ED G Sbjct: 4764 VTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAG 4821 Query: 2448 VYMCRASNLLG 2458 +Y C N LG Sbjct: 4822 LYRCTILNDLG 4832 Score = 41.9 bits (94), Expect = 0.012 Identities = 33/133 (24%), Positives = 54/133 (40%), Gaps = 7/133 (5%) Query: 1544 RSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA---PICTTSLKNVEIKEGQRAHFERR 1600 R+T +AGL + +L D + M D +A P + +++ EG E Sbjct: 4814 RTTLEDAGLYRCTILNDLGT--ASSMADLSVNRALTKPEVAEKMTDIDAVEGTEVRLE-- 4869 Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 +I KVEW+ +N L + R+T + L I +C D+G Y N G Sbjct: 4870 VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCTTNDTGPYKVIGTNECGI 4929 Query: 1661 AVTSGIAIVHSKK 1673 I+H ++ Sbjct: 4930 GGAVLNLIIHERE 4942 Score = 41.9 bits (94), Expect = 0.012 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 2/112 (1%) Query: 1294 AARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI 1353 +A+ Q++ +AP F + L EG V C++ G +EW +G + Sbjct: 5232 SAKFDVQIQAPEAAPKAPAFLKQLLPQNAREGDVVKFSCKV--TGYPEPEIEWTRDGVSM 5289 Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 ++ R Y+ ++ L + + DSG+Y C N G A +S L V K Sbjct: 5290 ESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK 5341 Score = 41.9 bits (94), Expect = 0.012 Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 2/112 (1%) Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021 +++ +Q + P F K + EG V +T +P +EW +G ++ Sbjct: 5233 AKFDVQIQAPEAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGYPEP--EIEWTRDGVSME 5290 Query: 2022 QGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 R T YD + L I A D+G Y C N G A +++ + V K+ Sbjct: 5291 SDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKT 5342 Score = 41.9 bits (94), Expect = 0.012 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 3/101 (2%) Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696 G Q P + ++K V G+ + +V + P KI W+K+ +TL + R + Sbjct: 5340 GKTQRPRLSDNMKELFATVGGEARF---EVTMKATPKPKICWYKDEITLRSRDRYTMKEE 5396 Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 G+ TL I ++ DSG Y A+N G+ +++ ++ Sbjct: 5397 DGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK 5437 Score = 41.5 bits (93), Expect = 0.016 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Query: 1056 VEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF-GYVALDIASVRAEDSG 1114 VE A F+ +E TVEWY +I S+ + + D G +L I + +D+G Sbjct: 3 VESGEARFDVTIEGYPK--PTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAG 60 Query: 1115 VYTVVARNAAGEAQLSASMTVETR 1138 Y VA N AG+ L ++V+ + Sbjct: 61 AYKCVATNDAGQTSLRGDLSVKEK 84 Score = 41.5 bits (93), Expect = 0.016 Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 2/99 (2%) Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033 V+ P+ + ++ +VTEG L ++ +PT+ EW N + RFKT +D Sbjct: 1311 VMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQ 1368 Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 L I D Y N GE +++ +KV K Sbjct: 1369 TGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK 1407 Score = 41.5 bits (93), Expect = 0.016 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 2/80 (2%) Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493 EG+ A F +L+ P+ +EWY+ ++ G R++ D L I +D G Y Sbjct: 1424 EGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTY 1481 Query: 3494 LCRAYNNYGEAVTTASMKVQ 3513 C A N G+ A ++V+ Sbjct: 1482 KCIASNEAGKVTQRAELEVK 1501 Score = 41.5 bits (93), Expect = 0.016 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 6/91 (6%) Query: 1585 KNVEIKEGQRA--HFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642 K + ++EGQ A + R P D VEWY + L S + G L+I Sbjct: 2103 KRIAVREGQNAITNMTIRARPSPD----VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKA 2158 Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673 +D+GTY C+A N++G I V + K Sbjct: 2159 TLDDAGTYICKATNSIGSTSRRIIVDVEALK 2189 Score = 41.5 bits (93), Expect = 0.016 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Query: 2388 IQEGQTAHFDCRLIPV-GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446 + EG+ A ++ V G P VEWF++ K + DS R+ + I HV EDE Sbjct: 3142 VNEGEEAQM---MVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDE 3198 Query: 2447 GVYMCRASNLLG 2458 G Y C AS+ G Sbjct: 3199 GSYKCVASSTNG 3210 Score = 41.5 bits (93), Expect = 0.016 Identities = 18/57 (31%), Positives = 32/57 (56%) Query: 4107 ARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163 +R P F+S +++ V+EG+ A+ C++ G P+P V W + I N R + + G Sbjct: 3683 SRVTPKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQLITNNDRVRSSVVG 3739 Score = 41.5 bits (93), Expect = 0.016 Identities = 20/63 (31%), Positives = 32/63 (50%) Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 V+ ++A P + P V +G A+F RV G P+P+V W IV+ RY+++ Sbjct: 3773 VIVVNRASITPRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWFHESTKIVSRGRYEIS 3832 Query: 4161 YDG 4163 G Sbjct: 3833 RVG 3835 Score = 41.5 bits (93), Expect = 0.016 Identities = 43/190 (22%), Positives = 75/190 (39%), Gaps = 29/190 (15%) Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397 G+ V W+ +G + R D L++ S+ ED+G Y C+A ++LG+ S Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031 Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVI 1457 C L D K ++ D +KP +TR Sbjct: 5032 CIL-------------------------DVQAVPKEEV-DHGQIVKP-VITRKIRDAQGE 5064 Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517 EG ++ FE ++ + VEW++ + G +++ G +L I + +D+G Y Sbjct: 5065 EGSNIRFEIHVKSHPPPH--VEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSY 5122 Query: 1518 TCRAVNLVGT 1527 A N G+ Sbjct: 5123 KVVATNQAGS 5132 Score = 41.5 bits (93), Expect = 0.016 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 3/93 (3%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA- 1369 P+ + L IE EG + L G RV+W+ I +R+ D +A Sbjct: 5640 PEINEKLKKIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMAS 5697 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + + ED G+Y C A N+ GE + L V Sbjct: 5698 LTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHV 5730 Score = 41.1 bits (92), Expect = 0.021 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 8/102 (7%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSINSLRND 2710 ++ EG+ V L+ + + P ++ W+K+G L T LKST D LSI + Sbjct: 99 EVFEGESVNLDLTITGKPKP--EVVWYKDGKPLRKTKSIDLKSTDDSYF--LSIPKATPN 154 Query: 2711 DSGIYTCKATNLLGEAVS--TASIKIEDRHWLLGESLHPDSL 2750 DSG Y C+A N +G + ++K++ + + L PD + Sbjct: 155 DSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPDKV 196 Score = 41.1 bits (92), Expect = 0.021 Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 4/97 (4%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYV 1768 P M+++ E A FE + G P + EW + IE S+R +TT Sbjct: 281 PEVVRKMENVESVEGSDAFFEVKF--KGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTS 338 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 +L + + +DSG Y C A NE GE + L V++K Sbjct: 339 SLVISDLRLDDSGAYQCIASNEAGECNLRADLKVKNK 375 Score = 41.1 bits (92), Expect = 0.021 Identities = 20/63 (31%), Positives = 32/63 (50%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 VEW+ +GK + + +R+ + +AL ++ ED G Y V N G +A + VE Sbjct: 761 VEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVE 820 Query: 1137 TRS 1139 RS Sbjct: 821 DRS 823 Score = 41.1 bits (92), Expect = 0.021 Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 5/106 (4%) Query: 776 LQDLGELQE--GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSL-NI 832 L+D GE + + T + +P V WYKDG + +SR T + + G + NI Sbjct: 2630 LEDDGEWSKVVRKGGFVNITFTLMGNPRPFVTWYKDGILLYDTSR-TDMRSRGDIQYCNI 2688 Query: 833 MHLRAEDAGSYTVRAVNKLGEAISTASIRV-AARSTVTADLGIPEQ 877 + ED G+Y A N+LG + + +I + +S + D P Q Sbjct: 2689 FFVGPEDTGTYVCEAHNRLGSSFRSCTIEIKEPKSVDSTDTRAPGQ 2734 Score = 41.1 bits (92), Expect = 0.021 Identities = 21/65 (32%), Positives = 34/65 (52%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 P I WY +G+ L+ R + S L ++++ D+G YTC+A N+ G A+ S Sbjct: 2863 PTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFE 2922 Query: 3001 VYCTS 3005 V T+ Sbjct: 2923 VDVTA 2927 Score = 41.1 bits (92), Expect = 0.021 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 2/70 (2%) Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA-LDIIHATSADTGEYTVRAVNHLGSAHT 1263 G P +++W NG+ V R +T YD G VA L I + D G Y A N G+ + Sbjct: 2960 GKPKPQIKWTKNGKPVESDGRLRTDYD-GIVAYLSIWQVSHDDAGTYECIASNAAGTVSS 3018 Query: 1264 SAIVRVIERS 1273 SA + V R+ Sbjct: 3019 SAALTVSRRN 3028 Score = 41.1 bits (92), Expect = 0.021 Identities = 53/241 (21%), Positives = 92/241 (38%), Gaps = 33/241 (13%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 ++T+++ P E N GG V+ ++ G+P + W+ +G +R Sbjct: 3371 DLTVKERLFGPEFLEEEGVWNKVAKAGGFVNISFTLK--GNPRPHVVWYRDGILLYDTTR 3428 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803 + + ++I + DAG Y C A ++ G+A R LE ++P M Sbjct: 3429 MDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAI----------RSCTLEIKVPS-M 3477 Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863 G + K++ + I + V E V+F+ R+ P + Sbjct: 3478 GGPEEKKISKALIGQGDNDVQAV----------------EGWKVQFQTRITGYPYP--HV 3519 Query: 3864 EWYRNGKLLPSGHRYRTVY--DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISC 3921 EWYR L +Y+ + G SL + V +D G Y C A N G + + Sbjct: 3520 EWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDV 3579 Query: 3922 K 3922 K Sbjct: 3580 K 3580 Score = 41.1 bits (92), Expect = 0.021 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 2/75 (2%) Query: 1585 KNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLP 1644 + + + EGQ + + ++ S L+V WY + + L+ R + L I S P Sbjct: 3595 QELNVPEGQEINMD--VVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAP 3652 Query: 1645 EDSGTYTCRAINALG 1659 EDSG Y C ++ LG Sbjct: 3653 EDSGLYKCEGVSTLG 3667 Score = 41.1 bits (92), Expect = 0.021 Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 4/101 (3%) Query: 902 VPESTQ-KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT 960 VP+ ++ P+F + + + + + EG A ++ G VEW KD + + + R+ + Sbjct: 3679 VPDGSRVTPKFLSHL-NSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRS 3735 Query: 961 FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 L ++V + D G Y C A N G ++SA + + Sbjct: 3736 SVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVV 3776 Score = 41.1 bits (92), Expect = 0.021 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 3/91 (3%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P+F++ + S + E ++ K C++ G P VEWF + + + + +R Sbjct: 3687 PKFLSHLNS-LDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCT 3743 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063 + F V +D G Y C ATN G + AVI Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVI 3774 Score = 41.1 bits (92), Expect = 0.021 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 4/84 (4%) Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS--IFNFGYVSLNIMHLRAEDAG 841 EG + ++T P VEW++ IT R + + + G SL I ++ ED+G Sbjct: 4270 EGWKVQLDTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSG 4327 Query: 842 SYTVRAVNKLGEAISTASIRVAAR 865 SY A N LGEA + A + V + Sbjct: 4328 SYRAVASNNLGEATTLAELTVKGK 4351 Score = 41.1 bits (92), Expect = 0.021 Identities = 23/97 (23%), Positives = 51/97 (52%), Gaps = 3/97 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P F+ ++++VT + G+ A F R+ P K+ W+ + +L + R+ + + Sbjct: 4551 PTFVERLREVTTVFGGE-ASFSVRVKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYN 4607 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 L I ++SG Y C+ +N +G+++ ++ L ++E Sbjct: 4608 LTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEE 4644 Score = 41.1 bits (92), Expect = 0.021 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P F L+ + G+ + V + P KI W+K+ L R + + L Sbjct: 4551 PTFVERLREVTTVFGGEASF---SVRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYN 4607 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 L+I ++ DDSG Y C +N +G+ + + +E Sbjct: 4608 LTIENVGRDDSGTYMCILSNAVGKETCRSQLVVE 4641 Score = 41.1 bits (92), Expect = 0.021 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 2/97 (2%) Query: 3830 PKFITQIKSHT-VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 P+FI + + V SEGV + +P+ + WY++G LL R T Sbjct: 4945 PEFIDEEGEYVKVVRSEGVA-NITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHY 5003 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925 L+I + +ED+G Y+C A + G+ F + + +P Sbjct: 5004 LNIFSLTSEDAGTYMCEARSKLGKCFRSCILDVQAVP 5040 Score = 41.1 bits (92), Expect = 0.021 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F + L +I EGD F + + P +EW+ +++P+ R ++ D V L + Sbjct: 5546 FTAPLQHIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVILLL 5603 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 T D+G++ C N G+ +S SL Sbjct: 5604 RQTNISDAGVFKCVLRNDLGTVASSASL 5631 Score = 41.1 bits (92), Expect = 0.021 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%) Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK-TIND 3611 E + PE + E A F+ L+ RV+W+ + +R T+ Sbjct: 5635 EGYSKPEINEKLKKIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTS 5692 Query: 3612 FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 G L I + Q D GLY C A N +GE T L V Sbjct: 5693 DGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHV 5730 Score = 40.7 bits (91), Expect = 0.028 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL-TYD 4162 + K P + + + V EGE +TG PKP V+W +G + L + D Sbjct: 82 KEKQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSIDLKSTD 141 Query: 4163 GMYHFDIPKTRQYDTGK 4179 Y IPK D+GK Sbjct: 142 DSYFLSIPKATPNDSGK 158 Score = 40.7 bits (91), Expect = 0.028 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 1720 IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPED 1779 I V E ++ + + + G PK V W ++G P+ + + L++ P D Sbjct: 98 IEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPND 155 Query: 1780 SGTYTCRAINELGEAVTSSTLFVQSK 1805 SG Y C A N++G + + V+ K Sbjct: 156 SGKYKCEAKNKIGTSARDFDVNVKVK 181 Score = 40.7 bits (91), Expect = 0.028 Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 3/102 (2%) Query: 630 EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689 EDR P + I ++ +E F G P +IEW I RF Sbjct: 820 EDRSLKP-EVITSMRDCDCVEEETASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVTE 876 Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 SL + L ++D+G Y C A +A G T+A L V + Sbjct: 877 EGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969 KPE +I + VE + + K +P+ IEW+ + G RF +T + Sbjct: 825 KPE-VITSMRDCDCVEEETASFHCEFSGKPEPE--IEWFCGPNPIVPGGRFHVTEEGNIQ 881 Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006 +L + D+ D+G Y C A N G+ T + + K Sbjct: 882 SLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 40.7 bits (91), Expect = 0.028 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 6/109 (5%) Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 R E+ + +EK P F + KD ID +G V+ V G P I W +G Sbjct: 910 RAELKV-NEKHFAPEFE-DWKDTIDALDGQDVNISTWVR--GKPKPEIVWLKDGEELRNT 965 Query: 3742 SRVHTLNDFGFI-ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789 V + +G + L + + DAG YTCRA N G + IT A Sbjct: 966 MHVQ-IKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEA 1013 Score = 40.7 bits (91), Expect = 0.028 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 2/78 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EGD+ C V +PTL EW NN+ L R+K+ D +L I + D+ Y Sbjct: 1328 EGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPY 1385 Query: 2847 TCKATNSKGSATTSGSLR 2864 N G ++S L+ Sbjct: 1386 KVVVRNDAGEVSSSAKLK 1403 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 4/84 (4%) Query: 2916 PIAAEHQLVEGQVLHLEGQVEP----KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTL 2971 PI E Q +E + + VE + P + W+ NGK L G ++ S + TL Sbjct: 1507 PIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTL 1566 Query: 2972 DLVDVYERDSGIYTCKAYNKRGEA 2995 ++ E D+G Y C A N G A Sbjct: 1567 YILRSEEEDAGSYKCLARNDVGSA 1590 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 5/105 (4%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--IT 959 + +S KPE +KD I E G A F+ +++ + VEW + R +T Sbjct: 1697 IVKSKSKPEILETMKDAEGI-ETGKAKFDVKIKAYPKA--EVEWYHRSARIYDGGRYCLT 1753 Query: 960 TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 G ++TI + + D G Y A+N IG+ + A LT+ K Sbjct: 1754 QDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 2/95 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F LK + EG F R+ +P+ + W +N I R + F L Sbjct: 1903 PSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETYKL 1960 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 + + I+D+G+Y C A + G A A + V R Sbjct: 1961 ILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Query: 904 ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN 963 E + P FK+ ++ I ++EGG E G ++W+KD PV R+ F+ Sbjct: 2428 EQWEAPSFKSQLQPVI-LEEGGTGVLVG--EVAGKPLPTIQWMKDDYPVLFGHRVRPQFD 2484 Query: 964 FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997 + + + D G Y C N G+A++ A Sbjct: 2485 GRTCKVIFREALIGDGGMYECIIKNQCGEASSKA 2518 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 4/74 (5%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED--SSRITKTHDFGYVSMTISHVRDED 2445 I EG + FD R+ G PT +VEWF + + D RI + G S+ +S V+ + Sbjct: 2540 IVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597 Query: 2446 EGVYMCRASNLLGE 2459 G Y ASN G+ Sbjct: 2598 TGHYRIVASNEHGK 2611 Score = 40.7 bits (91), Expect = 0.028 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 3858 DPKLRIEWYRNGKLLPSGHR--YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT 3915 +P+ + WY++G LL R R+ D+ + + I +V ED+G Y+C A N G F Sbjct: 2655 NPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCN--IFFVGPEDTGTYVCEAHNRLGSSFR 2712 Query: 3916 KATISCKK 3923 TI K+ Sbjct: 2713 SCTIEIKE 2720 Score = 40.7 bits (91), Expect = 0.028 Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 4/108 (3%) Query: 2795 CNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSLDITHTYEEDSGIYTCKATN 2852 C+V + + IEWF L G +YK + D +SL + + ED+G Y C Sbjct: 2754 CDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHT 2813 Query: 2853 SKGSATTSGSLRCTGDKN--IYFDTQHPQGKAGLEAVEQAEEARLAKG 2898 G T G L + ++ D + Q K L ++ ++ G Sbjct: 2814 PAGQTTIRGELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTG 2861 Score = 40.7 bits (91), Expect = 0.028 Identities = 27/99 (27%), Positives = 38/99 (38%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 +EK +AP+F + E + T T P + WY +G+ L R Sbjct: 2827 KEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRIDIRS 2886 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 L I PED+G Y C A N G A + + V Sbjct: 2887 RGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925 Score = 40.7 bits (91), Expect = 0.028 Identities = 31/128 (24%), Positives = 48/128 (37%), Gaps = 3/128 (2%) Query: 4092 ASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 A+ V+ + S+ P+ + EG+ ARF VTGHP P V W + I Sbjct: 3012 AAGTVSSSAALTVSRRNMRPLITHKLHDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGI 3071 Query: 4152 VNGSRYKLTYD---GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRG 4208 G RY+L + G + + D G + + L VI R Sbjct: 3072 SEGRRYQLMSNEEQGKHSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIARDFGPEF 3131 Query: 4209 VLKNAPRP 4216 + +P+P Sbjct: 3132 DEEESPKP 3139 Score = 40.7 bits (91), Expect = 0.028 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 9/130 (6%) Query: 1408 LILESQHP--SGLEKIQYLEDTSRYKKT-DI---IDESVTIKPRFVTRPKSIENVIEGQH 1461 L++ S P SGL K + + KT D+ + + + P+F++ S++ V EG Sbjct: 3645 LVIPSAAPEDSGLYKCEGVSTLGTSSKTFDVKAGVPDGSRVTPKFLSHLNSLD-VDEGDS 3703 Query: 1462 VHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521 CK+ + VEWFK+ Q +T R R L + +D G Y C A Sbjct: 3704 AKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTA 3761 Query: 1522 VNLVGTDEVS 1531 N G+ S Sbjct: 3762 TNQEGSTSSS 3771 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P P D+ + + A F R+ +V WFH +++ R + L Sbjct: 3783 PRIIEKPRDVDAVDGTDAKFTVRV--EGFPQPKVTWFHESTKIVSRGRYEISRVGDLYSL 3840 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 I GV G Y C ATN G+ T C L V Sbjct: 3841 VIRGVEYLHVGTYKCIATNDAGKVTAHCHLDV 3872 Score = 40.7 bits (91), Expect = 0.028 Identities = 20/70 (28%), Positives = 34/70 (48%) Query: 2136 INDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVN 2195 + +P + WF +G ++ R L+I +D+GTY+C+A ++LG Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236 Query: 2196 TCTLKVAGHR 2205 +CTL V R Sbjct: 4237 SCTLDVKAVR 4246 Score = 40.7 bits (91), Expect = 0.028 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 4/93 (4%) Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSRFTE 1628 V E AP L + EG+ E + ++ L KVEW+ N+KP+K Sbjct: 4745 VPEEDWSAPSFVIELTPTTVTEGESTALE---VEITGTPLPKVEWFKNDKPVKHDHLVRS 4801 Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 + + L + ED+G Y C +N LG A Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTA 4834 Score = 40.7 bits (91), Expect = 0.028 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P F Y K+V + V R +P ++ W+K+G L+ R+ + Sbjct: 4945 PEFIDEEGEYVKVVRSEGV-ANITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHY 5003 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 L+I SL ++D+G Y C+A + LG+ + + ++ Sbjct: 5004 LNIFSLTSEDAGTYMCEARSKLGKCFRSCILDVQ 5037 Score = 40.7 bits (91), Expect = 0.028 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 2/86 (2%) Query: 780 GELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAE 838 G + R +T P V WYKDG I +SR I + G V L I+ ++E Sbjct: 5157 GPITITRGNQLNLNVTIRGKPKPSVVWYKDGNKIL-TSRNVQIRSCGDVYHLIILFTKSE 5215 Query: 839 DAGSYTVRAVNKLGEAISTASIRVAA 864 AG+Y+ A +KLG + +++ A Sbjct: 5216 HAGTYSCEATSKLGNTSAKFDVQIQA 5241 Score = 40.3 bits (90), Expect = 0.037 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114 + EG +V + T+ EW N + ++ +R +T D L I +V D+ Sbjct: 1326 VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAV 1383 Query: 1115 VYTVVARNAAGEAQLSASMTV 1135 Y VV RN AGE SA + V Sbjct: 1384 PYKVVVRNDAGEVSSSAKLKV 1404 Score = 40.3 bits (90), Expect = 0.037 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 3/113 (2%) Query: 3812 ERGRISDAPKEEPIVS-TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK 3870 + G +S + K + I T P+ + ++K E + F ++ P IEWY Sbjct: 1392 DAGEVSSSAKLKVIRKCTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPD--IEWYYGTT 1449 Query: 3871 LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 + G RY+ D SL I + +D G Y C A N+ G+ +A + K+ Sbjct: 1450 RIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKE 1502 Score = 40.3 bits (90), Expect = 0.037 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 3/98 (3%) Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969 KPE ++ + + VEG ++ PD IEWY+ + G R+K + D Sbjct: 1410 KPE-VLEKMKDVKGVEGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKY 1466 Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007 +L + D+ +D G Y C A N+ G+ + + +D Sbjct: 1467 SLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKERD 1504 Score = 40.3 bits (90), Expect = 0.037 Identities = 22/95 (23%), Positives = 41/95 (43%) Query: 2364 RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS 2423 R E+ +Q P+F + + Q + G PT + W+++ + ++D+ Sbjct: 2821 RGELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTR 2880 Query: 2424 RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 RI + I +++ ED G Y C A N +G Sbjct: 2881 RIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIG 2915 Score = 40.3 bits (90), Expect = 0.037 Identities = 59/249 (23%), Positives = 102/249 (40%), Gaps = 27/249 (10%) Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234 S P F L P EG+ + G+P VEWF + + RF+TY+D G Sbjct: 3230 SLPAFSSKL-RPLETLEGEKTKFVVNVS--GEPIPTVEWFKDDTPIKHEDRFRTYFD-GR 3285 Query: 1235 VALDIIHAT-SADTGEYTVRA---------VN-HLGSAHTSAIVRV-IERSD----IVTD 1278 V + + T S + E + A V LGSA R +E++D +V Sbjct: 3286 VCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVIS 3345 Query: 1279 TQNEQAIEQIQLLEDAARRTKQVREDITVMQ---APQF--SRALHNIETVEGTNVHLECR 1333 + + +++ + D+TV + P+F + N G V++ Sbjct: 3346 NLHMEDTGPYKIIATNEHGSTGSVVDLTVKERLFGPEFLEEEGVWNKVAKAGGFVNISFT 3405 Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393 L+ G+ V W+ +G + R D +++ + ED+G Y C+A +++G Sbjct: 3406 LK--GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGT 3463 Query: 1394 AVTSCALRV 1402 A+ SC L + Sbjct: 3464 AIRSCTLEI 3472 Score = 40.3 bits (90), Expect = 0.037 Identities = 20/81 (24%), Positives = 37/81 (45%) Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792 +E A+ + + +PT++W A + + +++ N L+I N + EDTG + Sbjct: 3297 FECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYK 3356 Query: 4793 CRATTAAGQVETSAKLVVKSK 4813 AT G + L VK + Sbjct: 3357 IIATNEHGSTGSVVDLTVKER 3377 Score = 40.3 bits (90), Expect = 0.037 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 1/69 (1%) Query: 4116 LPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY-HFDIPKTRQ 4174 +P+ + V EG V G P P V W +G + N + L G Y + D+ KT Q Sbjct: 3886 MPEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQ 3945 Query: 4175 YDTGKIEVI 4183 D+G + + Sbjct: 3946 ADSGTYKFV 3954 Score = 40.3 bits (90), Expect = 0.037 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501 + P F + +S++ V E + F C++ +++WF N QPV+ R D Sbjct: 4453 LAPGFKSALRSLD-VTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPV 4509 Query: 1502 VALDIIDLIAEDSGIYTCRAVN 1523 L I +D+G+Y C AVN Sbjct: 4510 HKLAITKATLQDTGVYKCLAVN 4531 Score = 40.3 bits (90), Expect = 0.037 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 2/92 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F+ L+ VT + GG+ F R++ G P KI W K+ + RF +L Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRVK--GFPRPKIVWYKDITRLINRGRFHISEEGDLYNL 4608 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + ++ DSG Y C +A G ++ L V Sbjct: 4609 TIENVGRDDSGTYMCILSNAVGKETCRSQLVV 4640 Score = 40.3 bits (90), Expect = 0.037 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 3/105 (2%) Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604 V+ PE E + P F + ++E S E + +VEWF N KP+ Sbjct: 4741 VEGHVPE-EDWSAPSFVIELTPTTVTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDH 4797 Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 V++ D + L + DAGLY C N G A+ L V Sbjct: 4798 LVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842 Score = 39.9 bits (89), Expect = 0.049 Identities = 54/204 (26%), Positives = 75/204 (36%), Gaps = 40/204 (19%) Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGE 3767 E G FD +E PT ++W+ + + L +D G +L I + DAG Sbjct: 4 ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61 Query: 3768 YTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVS 3827 Y C ATN G + ++ V E Q+ +IKE E +EPI Sbjct: 62 YKCVATNDAGQTSLRGDLS-------VKEKQI-----APQIKEKE---------QEPI-- 98 Query: 3828 TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887 V E E V + + K PK + WY++GK L Sbjct: 99 ------------EVFEGESVNLDLTITGK--PKPEVVWYKDGKPLRKTKSIDLKSTDDSY 144 Query: 3888 SLDILYVYAEDSGEYICRAVNDFG 3911 L I DSG+Y C A N G Sbjct: 145 FLSIPKATPNDSGKYKCEAKNKIG 168 Score = 39.9 bits (89), Expect = 0.049 Identities = 26/123 (21%), Positives = 55/123 (44%), Gaps = 5/123 (4%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 + V+E +I+P + + + VFEG++ + + + P + +Y +GK L+ Sbjct: 79 LSVKEKQIAP-QIKEKEQEPIEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKTKSI 135 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGS--IISESQRPEG 2349 + L I P D+G+Y +A N +G + V KG ++ +P+ Sbjct: 136 DLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPDK 195 Query: 2350 LEK 2352 +++ Sbjct: 196 VQE 198 Score = 39.9 bits (89), Expect = 0.049 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 3/119 (2%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRT-DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERR 1600 I ++T N++G + + R D+ +V +AP T+ LK +++EG++ F Sbjct: 148 IPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPDKVQEGEQYKFTCA 207 Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 + + WY + +P+K+ R ++ + L I +D GTY N LG Sbjct: 208 VTGKPKPV--ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLG 264 Score = 39.9 bits (89), Expect = 0.049 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 3/88 (3%) Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG-YVSLNIMHLRAEDA 840 ++EGR A +++ P+ V WYKD I R I++ G I R ED Sbjct: 1226 VKEGREASVYFEISGKPKPS--VTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDK 1283 Query: 841 GSYTVRAVNKLGEAISTASIRVAARSTV 868 G+Y A N +G A T I V + V Sbjct: 1284 GTYKCEARNDVGTAFETFPIDVEVKQEV 1311 Score = 39.9 bits (89), Expect = 0.049 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 V W+ NGK L G V+ + + L I + DAG Y C A N G A ++QV+ Sbjct: 1540 VTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVE 1599 Query: 3651 GRQGIILEPQLPSHFKSG--TES 3671 G + P+L S +S TES Sbjct: 1600 GVKPKEEAPKLTSQLRSARITES 1622 Score = 39.9 bits (89), Expect = 0.049 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 3/84 (3%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 +PV + + + + EG TA + ++ V PT VEW+ + D R T + Y Sbjct: 1998 KPVIKEVSKTFE-VSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYH 2054 Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458 +++I V D+ Y C A N G Sbjct: 2055 TLSIRDVGDQAAASYKCVAFNNAG 2078 Score = 39.9 bits (89), Expect = 0.049 Identities = 49/225 (21%), Positives = 83/225 (36%), Gaps = 16/225 (7%) Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135 G+ + W+ +G + + R + I D+GTY C A N+ G + S Sbjct: 2654 GNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRS 2713 Query: 3136 VKLE-----CVDKSKGQKPRF---TTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187 +E VD + + P H + EG+ G++ C V+ + IEW+ Sbjct: 2714 CTIEIKEPKSVDSTDTRAPGQLIPVKHKFDFEGVPGGKA---RCDVLVKKSDIIDIEWFR 2770 Query: 3188 NGQPMRHSTRIKTV-SDFGFVV-LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKG 3245 +R + K + SD G + L + D+G Y C + G+ R ++ K Sbjct: 2771 GTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHIKEK- 2829 Query: 3246 GVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQD 3290 L D + QG + T + P IT +D Sbjct: 2830 --QQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKD 2872 Score = 39.9 bits (89), Expect = 0.049 Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 9/83 (10%) Query: 799 DPTMRVEWYKDGRPITASSR--ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856 +P V WY+DG + ++R I S + YV NI L EDAG+Y A +++G AI Sbjct: 3409 NPRPHVVWYRDGILLYDTTRMDIRSRGDLHYV--NIYGLTLEDAGNYVCEARSRIGTAIR 3466 Query: 857 TASIRVAARSTVTADLGIPEQRR 879 + ++ + S +G PE+++ Sbjct: 3467 SCTLEIKVPS-----MGGPEEKK 3484 Score = 39.9 bits (89), Expect = 0.049 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 4/106 (3%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102 P+FL L + + EG SA ++ + + TVEW+ + + IT+ +R+++ Sbjct: 3687 PKFLSHLNSLD-VDEGDSAKLTCKMFGKPE--PTVEWFKDDQLITNNDRVRSSVVGNTCT 3743 Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148 L +V +D G Y A N G SA + V R+SI I + Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVIVV-NRASITPRIIEK 3788 Score = 39.9 bits (89), Expect = 0.049 Identities = 23/60 (38%), Positives = 29/60 (48%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 V WF +G L SR+ + L I G+ DAG Y C+A +R G SC L VK Sbjct: 4184 VFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVK 4243 Score = 39.9 bits (89), Expect = 0.049 Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%) Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578 ++ E + A + V G P+ R +W++N + SR T+ D L I D Sbjct: 4465 DVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDT 4522 Query: 2579 GLYMCKAINRAG 2590 G+Y C A+N G Sbjct: 4523 GVYKCLAVNDNG 4534 Score = 39.9 bits (89), Expect = 0.049 Identities = 57/234 (24%), Positives = 89/234 (38%), Gaps = 34/234 (14%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+FI + + K+V + +P +V W+ +G L R T Sbjct: 4945 PEFIDEEGEYVKVVRSEGVA-NITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHY 5003 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401 L+I E++G Y C A +KLG KC + ILD Q + K + Sbjct: 5004 LNIFSLTSEDAGTYMCEARSKLG--------KCF--RSCILDVQ-------AVPKEEVDH 5046 Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461 +V+ PV T + + + EG N FE + P VEWY Sbjct: 5047 GQIVK-------------PVITRKIRDAQG-EEGSNIRFEIHVKSHPPP--HVEWYRGSI 5090 Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 L G +++ G L I+ +D+G Y A N G + + A + V+ K Sbjct: 5091 KLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDK 5144 Score = 39.9 bits (89), Expect = 0.049 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 EG+ ++ P P+ V+WY GK+L + S + I + E SG Y Sbjct: 5456 EGREVELSTVVKGLPRPS--VKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRY 5513 Query: 1918 TCKAINNLGQAVSSIRLNVQSK 1939 C+A N+ G A LN+Q++ Sbjct: 5514 RCEATNSNGTAHRDFVLNIQAQ 5535 Score = 39.9 bits (89), Expect = 0.049 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 4/97 (4%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR-TFCDFGFV 3478 P L IE GE A F+ +T P +V+WY + +R+ T G Sbjct: 5640 PEINEKLKKIEAFEGGE-ARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMA 5696 Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 L I ED G Y C A N YGE + + V K Sbjct: 5697 SLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733 Score = 39.5 bits (88), Expect = 0.065 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 8/107 (7%) Query: 1036 EVKITQ---KPRFLGPLKGTNKIVEGQSA-HFEARVEPQSDLTMTVEWYFNGKQITSANR 1091 EVK+ KP + ++ + + E ++ H E +P+ + +EW+ I R Sbjct: 816 EVKVEDRSLKPEVITSMRDCDCVEEETASFHCEFSGKPEPE----IEWFCGPNPIVPGGR 871 Query: 1092 IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 + +L I+ ++ ED+G Y VA NAAG+ A + V + Sbjct: 872 FHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918 Score = 39.5 bits (88), Expect = 0.065 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 3/92 (3%) Query: 2499 EEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR 2558 E ++ + P F L P E+ EG V G P +W+ + V +K RF+ Sbjct: 1012 EALQKKGDTPTFMSKLE-PIEITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFK 1068 Query: 2559 TTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 ++D L + +D G+Y C N G Sbjct: 1069 ASYDGNVSALTVKEAELDDDGVYKCVVTNNFG 1100 Score = 39.5 bits (88), Expect = 0.065 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%) Query: 1302 REDITVMQA---PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR 1358 + D+TV++ P+ + + ++ TVEG + ++ +EW+ I G R Sbjct: 1105 KADVTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGR 1162 Query: 1359 FRPAYEFDYVALDLL--SVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 F+ + + + L V +D+G C ATN G+ V L V K Sbjct: 1163 FKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211 Score = 39.5 bits (88), Expect = 0.065 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 6/98 (6%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL---TTMHDFGY 1767 P M D+R E A+F ++ PK +EW I R T + Y Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAF--PKPEIEWYLGATKITDGGRFKIKTDKENCSY 1174 Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + L + V +D+GT C A N G+ V + L V+ K Sbjct: 1175 I-LFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211 Score = 39.5 bits (88), Expect = 0.065 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 6/95 (6%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF---TSIFRFGY 693 P+ + + V +EGGK +F +I+ P +IEW I RF T Y Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSY 1174 Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 I L + + + D+G C A +A G +A L V Sbjct: 1175 I-LFIDDVKLDDAGTVKCSATNAAGKTVVRADLEV 1208 Score = 39.5 bits (88), Expect = 0.065 Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 6/125 (4%) Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468 D V++E AP L E++ EG++ +++ +P L EW N + L R Sbjct: 1304 DVEVKQEVMIAPEIRQQLQ-AEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDR 1360 Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK--RNIILESQLP- 3525 F+T D L I D+ Y N+ GE ++A +KV K + +LE Sbjct: 1361 FKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDV 1420 Query: 3526 KGMEG 3530 KG+EG Sbjct: 1421 KGVEG 1425 Score = 39.5 bits (88), Expect = 0.065 Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 4/107 (3%) Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM- 4164 K P V + D VE G+ A F +++G+P P + W I +G RYK + D Sbjct: 1407 KCTKPEVLEKMKDVKGVE-GDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQK 1465 Query: 4165 YHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLK 4211 Y I D G + I L+V R DY + + Sbjct: 1466 YSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKER--DYAPIFE 1510 Score = 39.5 bits (88), Expect = 0.065 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 2/95 (2%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 PE D+ E A F +L S +EW++ + G R K D L Sbjct: 1411 PEVLEKMKDVKGVEGDEATFNVKLSGY--PSPDIEWYYGTTRIRDGGRYKFSRDDQKYSL 1468 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 I + +D G Y C A+N G+ T +L+VK R Sbjct: 1469 TIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKER 1503 Score = 39.5 bits (88), Expect = 0.065 Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 +AP+ +QL +++E C ++ PDP+ EW + K ++ +S D Sbjct: 1606 EAPKLTSQLRS-ARITESDDFELACDVKGTPDPSY--EWLKDDKPVKFDRHLSSSFDGKK 1662 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV---QSKESIIRDSQHESALE 1953 L+ V D G YT N G SS L++ +SK I+ + +E Sbjct: 1663 CTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSKPEILETMKDAEGIE 1717 Score = 39.5 bits (88), Expect = 0.065 Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 4/83 (4%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFN-NKPLPSGTRYKSTHDFSYVSLD 2834 F + L I EG+N F C V +P+ + W+ N N+ +P G R ++T D L Sbjct: 1905 FTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDG-RSRTTFDGETYKLI 1961 Query: 2835 ITHTYEEDSGIYTCKATNSKGSA 2857 + +D+G Y C A+N G A Sbjct: 1962 LQDIKIKDAGQYECIASNPIGKA 1984 Score = 39.5 bits (88), Expect = 0.065 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 4/94 (4%) Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLNDFGFIALD 3756 +E + + EG FD R+ G PT ++WF+ G R+ + + G +L Sbjct: 2532 IEKPAGLVIVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLV 2589 Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 + + G Y A+N+ G A +T + + Sbjct: 2590 VSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER 2623 Score = 39.5 bits (88), Expect = 0.065 Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 4/77 (5%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSLDITHTYE 2840 +V EG++ F+ + PT ++EWF+ ++ L G +Y+ S + SL ++ Sbjct: 2538 LVIVEGNDSRFDVRIRGH--PTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQL 2595 Query: 2841 EDSGIYTCKATNSKGSA 2857 + +G Y A+N G A Sbjct: 2596 DQTGHYRIVASNEHGKA 2612 Score = 39.5 bits (88), Expect = 0.065 Identities = 21/66 (31%), Positives = 31/66 (46%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P +EWF L G R + L TL I++L +D+G Y ATN G S Sbjct: 3312 PRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVD 3371 Query: 2732 IKIEDR 2737 + +++R Sbjct: 3372 LTVKER 3377 Score = 39.5 bits (88), Expect = 0.065 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 5/84 (5%) Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777 +++ V E Q + + ++ P+L V W ++G ++ + R+ + L + P Sbjct: 3595 QELNVPEGQEINMD--VVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAP 3652 Query: 1778 EDSGTYTCRAINELGEAVTSSTLF 1801 EDSG Y C ++ LG TSS F Sbjct: 3653 EDSGLYKCEGVSTLG---TSSKTF 3673 Score = 39.5 bits (88), Expect = 0.065 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Query: 2920 EHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYER 2979 E + EGQ ++++ V K+ P L++ WY +G++L+ R + S L + Sbjct: 3596 ELNVPEGQEINMD--VVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPE 3653 Query: 2980 DSGIYTCKAYNKRG 2993 DSG+Y C+ + G Sbjct: 3654 DSGLYKCEGVSTLG 3667 Score = 39.5 bits (88), Expect = 0.065 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 2/92 (2%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P+F + + L + E SA C++ + + VEWF + + + RV++ L Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTL 3744 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 V +D G Y C ATN+ G + S + V Sbjct: 3745 IFETVNIQDRGAYRCTATNQEGSTSSSAVIVV 3776 Score = 39.5 bits (88), Expect = 0.065 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 2/89 (2%) Query: 1848 TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL 1907 +++ P + EG + P P VEW+ +G++L + + + LD+L Sbjct: 3884 SEMPEPIVVREGCEVSMMANVRGKPAPT--VEWFKDGQLLSNTNNLHLRARGEYFNLDLL 3941 Query: 1908 TVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 DSG Y A N+LG A LNV Sbjct: 3942 KTTQADSGTYKFVATNDLGSAYRIFNLNV 3970 Score = 39.5 bits (88), Expect = 0.065 Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 3/90 (3%) Query: 2501 PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTT 2560 P ++ PIF L+ P + EG + + A V V PS +WY + + R RT Sbjct: 3975 PKEKWSSPIFVTELS-PLSVTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTF 4031 Query: 2561 HDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 D V L I + D G Y N +G Sbjct: 4032 FDGHVVKLLIGQITLEDQGQYKVVLKNESG 4061 Score = 39.5 bits (88), Expect = 0.065 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F+ L ++ EG F + G P I+W K+ I ++ R + F + L Sbjct: 3982 PIFVTELSPLSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKL 4039 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + + ++D G+Y + +G A + A L V Sbjct: 4040 LIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071 Score = 39.5 bits (88), Expect = 0.065 Identities = 21/68 (30%), Positives = 34/68 (50%) Query: 797 VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856 + +P V W+KDG + +SR+ LNI L +DAG+Y A ++LG Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236 Query: 857 TASIRVAA 864 + ++ V A Sbjct: 4237 SCTLDVKA 4244 Score = 39.5 bits (88), Expect = 0.065 Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK---LTYDGMYHFDIPKTRQYD 4176 VT EG + R+TG+P P V W I +G RYK + +G+Y I + D Sbjct: 4266 VTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLED 4325 Query: 4177 TGKIEVIXXXXXXXXXXXXXLKVIPRH 4203 +G + L V +H Sbjct: 4326 SGSYRAVASNNLGEATTLAELTVKGKH 4352 Score = 39.5 bits (88), Expect = 0.065 Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 4/111 (3%) Query: 643 LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702 L+ V +EG ++ T ++ G P ++W K G+ + S T + + S Sbjct: 5449 LEQVVGVEGREVELSTVVK--GLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAK 5506 Query: 703 IQDSGEYTCRAVSATGVAETKAVLHVTPRATIER--TSQHPETLQYIQQLE 751 + SG Y C A ++ G A VL++ + E+ LQ+I LE Sbjct: 5507 HEHSGRYRCEATNSNGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDILE 5557 Score = 39.5 bits (88), Expect = 0.065 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Query: 2505 FEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTT-HDF 2563 + KP + L E +EG A ++ V G P R +WY ++ +R+ +T Sbjct: 5637 YSKPEINEKLK-KIEAFEGGEARFDLLVT--GFPPPRVDWYRGTTKITDCNRYSSTLTSD 5693 Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590 G +L I + D GLY C A+N G Sbjct: 5694 GMASLTIRKIRQEDGGLYGCVAVNEYG 5720 Score = 39.1 bits (87), Expect = 0.086 Identities = 19/75 (25%), Positives = 36/75 (48%) Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443 +++ I+ + + RL G+P +V W+++ + D+ ++ ++I Sbjct: 385 DLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKAST 444 Query: 2444 EDEGVYMCRASNLLG 2458 DEG Y C ASN LG Sbjct: 445 NDEGQYFCEASNPLG 459 Score = 39.1 bits (87), Expect = 0.086 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 3/100 (3%) Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763 +E + Q P F +K I V + A + G PK +V W ++ VP+ + + Sbjct: 625 NEKVVQ-PEFDKEVKPIEVKHGEEATTSLEI--KGKPKPKVTWYKDLVPLLETRSIQLKS 681 Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 L + P+D G Y C A N+ G A S + V+ Sbjct: 682 VGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVK 721 Score = 39.1 bits (87), Expect = 0.086 Identities = 19/55 (34%), Positives = 25/55 (45%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G P EW+ + G RF T + +L I+ + DAG Y C A N AG Sbjct: 851 GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAG 905 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 3/100 (3%) Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028 K P F+++++ + E + + C + G P +V+WF + + RF YD Sbjct: 1017 KGDTPTFMSKLEP-IEITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFKASYDG 1073 Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068 A+ +D G Y C TN +G +KA + K Sbjct: 1074 NVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P Q LQ +++ EG C++ +PTL EW +N +L+ D+ R D + Sbjct: 1315 PEIRQQLQ-AEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGT 1371 Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459 +TI +V D Y N GE Sbjct: 1372 LTIRNVTLADAVPYKVVVRNDAGE 1395 Score = 39.1 bits (87), Expect = 0.086 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 5/93 (5%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 P+ +EW N ++L RFK D TL + +V D+ Y N GE +S+ Sbjct: 1342 PEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAK 1401 Query: 3001 V----YCTSKDNLIERTQHPKGTEGLEKIQNLE 3029 + CT K ++E+ + KG EG E N++ Sbjct: 1402 LKVIRKCT-KPEVLEKMKDVKGVEGDEATFNVK 1433 Score = 39.1 bits (87), Expect = 0.086 Identities = 22/67 (32%), Positives = 31/67 (46%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 P + W+ N K L G + +Y +L I + EED+G Y C A N GSA Sbjct: 1536 PKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFE 1595 Query: 2863 LRCTGDK 2869 ++ G K Sbjct: 1596 VQVEGVK 1602 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 2/94 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 +AP F L + EG L + G ++W + P+ GHR RP ++ Sbjct: 2431 EAPSFKSQLQPVILEEGGTGVLVGEV--AGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTC 2488 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 + D G+Y C NQ GEA + + V Sbjct: 2489 KVIFREALIGDGGMYECIIKNQCGEASSKALVGV 2522 Score = 39.1 bits (87), Expect = 0.086 Identities = 20/72 (27%), Positives = 34/72 (47%) Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396 +G+ V W+ +G + R D ++ V PED+G Y C+A N+LG + Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFR 2712 Query: 1397 SCALRVIAKKDL 1408 SC + + K + Sbjct: 2713 SCTIEIKEPKSV 2724 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR--TTHDFG 2564 +P+ T L + +EG+ A ++ V G PS EW+ + G R++ + + G Sbjct: 3030 RPLITHKLHD-MKAYEGKEARFDIEVT--GHPSPTVEWFKGPSGISEGRRYQLMSNEEQG 3086 Query: 2565 FVTLDINSVVANDAGLYMCKAINRAG 2590 +L ++ + A+D G+Y C A N AG Sbjct: 3087 KHSLIVSDLNADDDGIYKCVAQNLAG 3112 Score = 39.1 bits (87), Expect = 0.086 Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 10/131 (7%) Query: 1541 DIVRSTQNEAGLEQIQVLEDRSKYHR------TDMVDEVTTQAPICTTSLKNVEIKEGQR 1594 D++++TQ ++G + D +R T + + +PI T L + + EG Sbjct: 3939 DLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTELSPLSVTEGDY 3998 Query: 1595 AHFERRLIPVSDATL-KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCR 1653 F + VS L ++WY ++ P+ S R + V L I ED G Y Sbjct: 3999 TKF---VAHVSGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVV 4055 Query: 1654 AINALGEAVTS 1664 N G A +S Sbjct: 4056 LKNESGSATSS 4066 Score = 39.1 bits (87), Expect = 0.086 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 2/90 (2%) Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911 GP ++ G + I P P+ V WY +G + + + + L IL Sbjct: 5157 GPITITRGNQLNLNVTIRGKPKPS--VVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKS 5214 Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 E +G Y+C+A + LG + + +Q+ E+ Sbjct: 5215 EHAGTYSCEATSKLGNTSAKFDVQIQAPEA 5244 Score = 39.1 bits (87), Expect = 0.086 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 6/100 (6%) Query: 3552 AESGNPPEFTTTPSDLILSENSSAHF--ECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI 3609 AE P FT + + E + F E +PV VEW+ + +P+ R++T Sbjct: 5538 AEQWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVPV----VEWYRDDRPVTRDHRLRTY 5593 Query: 3610 NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 +D VIL + DAG++ C N G S L V Sbjct: 5594 SDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/70 (34%), Positives = 33/70 (47%) Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261 E G P VEW+ + R VT R +TY D V L + +D G + N LG+ Sbjct: 5566 EITGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTV 5625 Query: 1262 HTSAIVRVIE 1271 +SA + V E Sbjct: 5626 ASSASLNVNE 5635 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 923 EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGH 981 E G A F+ +E T VEW + + +S + + G +L IK +T DAG Sbjct: 4 ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61 Query: 982 YTCRAYNAIGQATTSANLTIVTKK 1005 Y C A N GQ + +L++ K+ Sbjct: 62 YKCVATNDAGQTSLRGDLSVKEKQ 85 Score = 38.7 bits (86), Expect = 0.11 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 3/78 (3%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSLDITHTYEEDSGI 2845 E F+ +E PT +EW+ + S ++K D SL I ++D+G Sbjct: 4 ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61 Query: 2846 YTCKATNSKGSATTSGSL 2863 Y C ATN G + G L Sbjct: 62 YKCVATNDAGQTSLRGDL 79 Score = 38.7 bits (86), Expect = 0.11 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 6/129 (4%) Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH-KNR 4021 DL +K+ P+ + Q + E E+ + L G P +V W+ +GKPL K+ Sbjct: 78 DLSVKEKQIAPQIKEKEQEPIEVFEGESVNLD--LTITGKPKPEVVWYKDGKPLRKTKSI 135 Query: 4022 FTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD--ETKAVIKTTGKPGIVYDSQLPK 4079 D Y ++ P DSG+Y C A N G + +K GK V P Sbjct: 136 DLKSTDDSYF-LSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPD 194 Query: 4080 HMKSIEKIR 4088 ++ E+ + Sbjct: 195 KVQEGEQYK 203 Score = 38.7 bits (86), Expect = 0.11 Identities = 28/112 (25%), Positives = 43/112 (38%), Gaps = 2/112 (1%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P LK EG + F + G P I W K+GQ I+A R F +L Sbjct: 185 PTVTSELKPDKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFDGTTSTL 242 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ 748 + + D G Y + G + A L VTP+ + E ++ ++ Sbjct: 243 LIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVE 294 Score = 38.7 bits (86), Expect = 0.11 Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 7/96 (7%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI--TASSRITSIFNFG 826 +P+F + ++ + E++ G A ++ P +V WYKD P+ T S ++ S+ + Sbjct: 630 QPEFDKEVKPI-EVKHGEEATTSLEIK--GKPKPKVTWYKDLVPLLETRSIQLKSVGDEH 686 Query: 827 YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 +L I++ +D G Y A NK G A + I+V Sbjct: 687 --TLEIINATPDDEGKYKCEATNKAGTAFRSFDIKV 720 Score = 38.7 bits (86), Expect = 0.11 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 6/94 (6%) Query: 3426 LSNIENLR--EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFG--FVILE 3481 L ++++R EG A+F ++ P ++EWY + G RF+ D IL Sbjct: 1120 LQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSYILF 1177 Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 I +D+G C A N G+ V A ++V+ K Sbjct: 1178 IDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211 Score = 38.7 bits (86), Expect = 0.11 Identities = 52/225 (23%), Positives = 87/225 (38%), Gaps = 40/225 (17%) Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495 + + V I P + + E+V EG CK+ + L EW KN + ++ RF+ Sbjct: 1307 VKQEVMIAPE-IRQQLQAEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKT 1363 Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555 D +G T R V L D V ++ R+ V S+ ++ Sbjct: 1364 RFD-------------GQTGTLTIRNVTLA--DAVPYKVVVRNDAGEVSSSA------KL 1402 Query: 1556 QVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYH 1615 +V+ +K P +K+V+ EG A F +L +EWY+ Sbjct: 1403 KVIRKCTK--------------PEVLEKMKDVKGVEGDEATFNVKLSGYPSPD--IEWYY 1446 Query: 1616 NNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 ++ G R+ + + +L I +D GTY C A N G+ Sbjct: 1447 GTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGK 1491 Score = 38.7 bits (86), Expect = 0.11 Identities = 21/65 (32%), Positives = 30/65 (46%) Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509 P V W+ NGK L+ G + L I + ED+G Y C A N+ G A Sbjct: 1536 PKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFE 1595 Query: 3510 MKVQG 3514 ++V+G Sbjct: 1596 VQVEG 1600 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 3/92 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P F T K I+ V EG++ F C++ + + V W++N + R R D Sbjct: 1903 PSFTTTLKPID-VTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETYK 1959 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 L + D+ +D+G Y C A N +G + +T Sbjct: 1960 LILQDIKIKDAGQYECIASNPIGKAFCTAEMT 1991 Score = 38.7 bits (86), Expect = 0.11 Identities = 52/221 (23%), Positives = 82/221 (37%), Gaps = 39/221 (17%) Query: 644 KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI 703 K+ EGG E ++ V PT +EW + RF Y +L + + Sbjct: 2006 KTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGD 2063 Query: 704 QDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIE 763 Q + Y C A + G T RA + T + +Y + ED+ E Sbjct: 2064 QAAASYKCVAFNNAG--------RTTYRADLVITER-----EYAPEFEDFD--------E 2102 Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823 ++ + R EG+NA +T + P+ VEWYK + + +I Sbjct: 2103 KRIAVR--------------EGQNAI--TNMTIRARPSPDVEWYKGDTLLMSDRKIDLKT 2146 Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864 G L I +DAG+Y +A N +G + V A Sbjct: 2147 IGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRIIVDVEA 2187 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 2/85 (2%) Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAG 3628 +SE +A E ++ V + VEW+H +L G R + + + L I V + A Sbjct: 2010 VSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAA 2067 Query: 3629 LYTCKATNRHGEATVSCKLQVKGRQ 3653 Y C A N G T L + R+ Sbjct: 2068 SYKCVAFNNAGRTTYRADLVITERE 2092 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK--TYYDFGFVALDIIHATSAD 1246 + EG + + R+ G PT VEWF+ +T G +++ + + G +L + Sbjct: 2540 IVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597 Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIER 1272 TG Y + A N G A + V ER Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTVNER 2623 Score = 38.7 bits (86), Expect = 0.11 Identities = 21/55 (38%), Positives = 27/55 (49%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G P + +W NG ++ R RT +D L I V +DAG Y C A N AG Sbjct: 2960 GKPKPQIKWTKNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAG 3014 Score = 38.7 bits (86), Expect = 0.11 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 5/98 (5%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN--DFGF 3752 P T ++ D + EG FD +E G P+ ++WF + G R ++ + G Sbjct: 3031 PLITHKLHD-MKAYEGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGK 3087 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 +L + + A D G Y C A N G A+T A + A+ Sbjct: 3088 HSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIAR 3125 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 2/85 (2%) Query: 3837 KSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV--YDMGFVSLDILYV 3894 K H ++ EG +E P +EW++ + G RY+ + + G SL + + Sbjct: 3036 KLHDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDL 3095 Query: 3895 YAEDSGEYICRAVNDFGEDFTKATI 3919 A+D G Y C A N G+ T+A + Sbjct: 3096 NADDDGIYKCVAQNLAGKASTRAML 3120 Score = 38.7 bits (86), Expect = 0.11 Identities = 52/252 (20%), Positives = 98/252 (38%), Gaps = 23/252 (9%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 G P ++WF +G+ R+ + L I ++ D G Y C A++ G ++ T Sbjct: 3156 GRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRT 3215 Query: 3783 AKITCSAKRDI------VLESQLP--QGMSGEKIKELERGRISDAP-----KEEPIVSTP 3829 ++ + S+L + + GEK K + P K++ + Sbjct: 3216 FDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHE 3275 Query: 3830 PKFITQIKSHT--VEESEGVRFEC---RVEPKED--PKLRIEWYRNGKLLPSGHRYRTVY 3882 +F T + + FEC R+E P+ +EW+ L G RYR Sbjct: 3276 DRFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQ 3335 Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL---PDIILQNQVPRGMKR 3939 +L I ++ ED+G Y A N+ G + ++ K+ P+ + + V + + Sbjct: 3336 TDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKERLFGPEFLEEEGVWNKVAK 3395 Query: 3940 SEALTQMEATIK 3951 + + T+K Sbjct: 3396 AGGFVNISFTLK 3407 Score = 38.7 bits (86), Expect = 0.11 Identities = 23/85 (27%), Positives = 34/85 (40%) Query: 777 QDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLR 836 +D EL + S P + V WYKDG + + RI + L I Sbjct: 3592 EDRQELNVPEGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAA 3651 Query: 837 AEDAGSYTVRAVNKLGEAISTASIR 861 ED+G Y V+ LG + T ++ Sbjct: 3652 PEDSGLYKCEGVSTLGTSSKTFDVK 3676 Score = 38.7 bits (86), Expect = 0.11 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 4/109 (3%) Query: 1965 KRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH 2024 K V D S V P+F + + +V EG L + +PT VEW+ + + + Sbjct: 3676 KAGVPDGSRVT--PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNND 3731 Query: 2025 RFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 R +++ L +D G Y C ATN G +++ + V+ S Sbjct: 3732 RVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNRAS 3780 Score = 38.7 bits (86), Expect = 0.11 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 6/106 (5%) Query: 1838 VAVNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894 + VN+A PR I + + +G A + R+E +P P +V W+ + S RY Sbjct: 3774 IVVNRASITPRIIEKPRDVDAV-DGTDAKFTVRVEGFPQP--KVTWFHESTKIVSRGRYE 3830 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 S +L I V G Y C A N+ G+ + L+V ++ Sbjct: 3831 ISRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQD 3876 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/93 (25%), Positives = 38/93 (40%), Gaps = 2/93 (2%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 +P F L + EG + G ++W+ + PI + HR R ++ V Sbjct: 3981 SPIFVTELSPLSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVK 4038 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + + ED G Y N+ G A +S L V Sbjct: 4039 LLIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071 Score = 38.7 bits (86), Expect = 0.11 Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 5/148 (3%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRT-DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERR 1600 I ++T + G+ + + D T D+ P L+ V G A F R Sbjct: 4514 ITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGEASFSVR 4573 Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 + K+ WY + L + RF + L I + +DSGTY C NA+G+ Sbjct: 4574 VKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGK 4631 Query: 1661 AVTSGIAIVHSKK--SIYLESQHEGALP 1686 +V +++ + E + +GA+P Sbjct: 4632 ETCRSQLVVEAEEFAPFFPEDEGQGAVP 4659 Score = 38.7 bits (86), Expect = 0.11 Identities = 33/130 (25%), Positives = 58/130 (44%), Gaps = 11/130 (8%) Query: 1266 IVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA---PQFSRALHNIET 1322 ++R+I R + D + + +L D T D++V +A P+ + + +I+ Sbjct: 4807 VIRLIVRRTTLEDA----GLYRCTILNDLG--TASSMADLSVNRALTKPEVAEKMTDIDA 4860 Query: 1323 VEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGV 1382 VEGT V LE + G +VEWF + + R+ + D L + + D+G Sbjct: 4861 VEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCTTNDTGP 4918 Query: 1383 YTCQATNQLG 1392 Y TN+ G Sbjct: 4919 YKVIGTNECG 4928 Score = 38.7 bits (86), Expect = 0.11 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 3/100 (3%) Query: 767 SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG 826 +QRP+ +++L G A FE +T + P ++ WYKD + + R T G Sbjct: 5342 TQRPRLSDNMKELFATVGGE-ARFE--VTMKATPKPKICWYKDEITLRSRDRYTMKEEDG 5398 Query: 827 YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866 +L I ++ D+G+Y A NK G+ + V ++ Sbjct: 5399 IYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKT 5438 Score = 38.7 bits (86), Expect = 0.11 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 3/99 (3%) Query: 906 TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965 TQ+P +K+ + GG A FE ++ ++ W KD + + R T G Sbjct: 5342 TQRPRLSDNMKELFATV-GGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDG 5398 Query: 966 YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 L IK V + D+G Y A N G+ T L ++ K Sbjct: 5399 IYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK 5437 Score = 38.7 bits (86), Expect = 0.11 Identities = 29/98 (29%), Positives = 39/98 (39%), Gaps = 2/98 (2%) Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGF 1634 TQ P + ++K + G A FE + K+ WY + L+S R+T G Sbjct: 5342 TQRPRLSDNMKELFATVGGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGI 5399 Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672 L I DSGTY A N G+ G V K Sbjct: 5400 YTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK 5437 Score = 38.7 bits (86), Expect = 0.11 Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 5/110 (4%) Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288 S + V E P + E FEG A F+ V P R+++Y + Sbjct: 5628 SASLNVNEGYSKPE--INEKLKKIEAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDC 5683 Query: 2289 ARFHITFDF-GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 R+ T G SL I+ ED G Y A+N G TS + + V K Sbjct: 5684 NRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733 Score = 38.7 bits (86), Expect = 0.11 Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 1077 VEWYFNGKQITSANRIQ-TYHDFGYVALDIASVRAEDSGVYTVVARNAAGE 1126 V+WY +IT NR T G +L I +R ED G+Y VA N GE Sbjct: 5671 VDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGE 5721 Score = 38.3 bits (85), Expect = 0.15 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%) Query: 1546 TQNEAGLEQIQVLEDRSKYH-RTDM-VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIP 1603 T+++AG + D + R D+ V E I + +E+ EG+ + + L Sbjct: 55 TKDDAGAYKCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGESVNLD--LTI 112 Query: 1604 VSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 +V WY + KPL+ + L I P DSG Y C A N +G Sbjct: 113 TGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIG 168 Score = 38.3 bits (85), Expect = 0.15 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 9/98 (9%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDF- 2697 AP F + D L +GQ V + V R P +I W K+G L T ++K D Sbjct: 921 APEFEDWKDTIDAL-DGQDVNISTWV--RGKPKPEIVWLKDGEELRNTMHVQIKCYGDLH 977 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 GLV ++ +D+G+YTC+A N G +I +E Sbjct: 978 GLVLYKVSP---EDAGMYTCRAKNNAGIVSKDVTITVE 1012 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 +GQ + + P P + W +G+ L++ + L + V ED+G Y Sbjct: 935 DGQDVNISTWVRGKPKPE--IVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMY 992 Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 TC+A NN G + + V++ + S LE I+ E D Sbjct: 993 TCRAKNNAGIVSKDVTITVEALQKKGDTPTFMSKLEPIEITEGD 1036 Score = 38.3 bits (85), Expect = 0.15 Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 8/131 (6%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD---FSYVSL 2833 + ++++ EG +F ++ P +IEW+ + G R+K D SY+ L Sbjct: 1120 LQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSYI-L 1176 Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893 I +D+G C ATN+ G L +KN+ QG+ ++ +A Sbjct: 1177 FIDDVKLDDAGTVKCSATNAAGKTVVRADLE-VEEKNVAPSFHGRQGRLRVKEGREASVY 1235 Query: 2894 RLAKGR-RPSV 2903 G+ +PSV Sbjct: 1236 FEISGKPKPSV 1246 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 4/85 (4%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFV 1635 P ++K+ E E +A F+ ++ A +VEWYH + + G R+ T+ G Sbjct: 1704 PEILETMKDAEGIETGKAKFDVKIKAYPKA--EVEWYHRSARIYDGGRYCLTQDEEDGTY 1761 Query: 1636 ALDIMSCLPEDSGTYTCRAINALGE 1660 ++ I ED GTY A N +G+ Sbjct: 1762 SVTINDLRLEDCGTYKIVAFNDIGK 1786 Score = 38.3 bits (85), Expect = 0.15 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDDSGIYTCKATNLL 2723 V+ + P ++EW+ + G R T D G +++IN LR +D G Y A N + Sbjct: 1725 VKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDI 1784 Query: 2724 GEAVSTASIKIEDR 2737 G+ A + ++++ Sbjct: 1785 GKTSERAELTVKEK 1798 Score = 38.3 bits (85), Expect = 0.15 Identities = 36/143 (25%), Positives = 59/143 (41%), Gaps = 13/143 (9%) Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC--DFGFVILEISPTYPEDSG 3491 EG ++ F+ R+ P +VEW++ + L G ++R + G L +S + +G Sbjct: 2542 EGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTG 2599 Query: 3492 EYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPE 3551 Y A N +G+A + V + L +G K+ G+ TL Sbjct: 2600 HYRIVASNEHGKAQALLDLTV--NERLYAPEFLED--DGEWSKVVRKGGFVNITFTL--- 2652 Query: 3552 AESGNPPEFTTTPSDLILSENSS 3574 GNP F T D IL ++S Sbjct: 2653 --MGNPRPFVTWYKDGILLYDTS 2673 Score = 38.3 bits (85), Expect = 0.15 Identities = 45/204 (22%), Positives = 77/204 (37%), Gaps = 30/204 (14%) Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781 +G+P + W+ +G SR + +I ++ D G Y C A N+ GS+ Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFR 2712 Query: 3782 TAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841 + I +IKE + +D ++ KF Sbjct: 2713 SCTI---------------------EIKEPKSVDSTDTRAPGQLIPVKHKF-------DF 2744 Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY--DMGFVSLDILYVYAEDS 3899 E G + C V K+ + IEW+R +L G +Y+ + D +SL + V ED+ Sbjct: 2745 EGVPGGKARCDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDA 2804 Query: 3900 GEYICRAVNDFGEDFTKATISCKK 3923 G Y C G+ + + K+ Sbjct: 2805 GTYRCVVHTPAGQTTIRGELHIKE 2828 Score = 38.3 bits (85), Expect = 0.15 Identities = 18/57 (31%), Positives = 30/57 (52%) Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001 + WY +G +L SR + S ++ V D+G Y C+A+N+ G +F S T+ Sbjct: 2660 VTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTI 2716 Score = 38.3 bits (85), Expect = 0.15 Identities = 23/93 (24%), Positives = 38/93 (40%) Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022 +L+ +K+Q P F+ + SQ + + G P + W+ +G+PL R Sbjct: 2823 ELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRI 2882 Query: 4023 TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055 + + PED+G Y C A N G Sbjct: 2883 DIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIG 2915 Score = 38.3 bits (85), Expect = 0.15 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 2/73 (2%) Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514 NV EGQ ++ + ++ + L+V W+K+G+ + R + L I EDS Sbjct: 3598 NVPEGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDS 3655 Query: 1515 GIYTCRAVNLVGT 1527 G+Y C V+ +GT Sbjct: 3656 GLYKCEGVSTLGT 3668 Score = 38.3 bits (85), Expect = 0.15 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%) Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301 P F + LR + V E ++A F C+V P RI+++ N + + +R + D Sbjct: 4455 PGFKSALR-SLDVTEDESAEFRCEVSG--SPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511 Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335 L I +D G Y A+N G TS + V+ Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVS 4545 Score = 38.3 bits (85), Expect = 0.15 Identities = 20/67 (29%), Positives = 33/67 (49%) Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371 P V W+ +G K+ + + L IL+ E++G Y C AT+KLG S K + Sbjct: 5177 PKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAKFD 5236 Query: 3372 LKCTSKE 3378 ++ + E Sbjct: 5237 VQIQAPE 5243 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 2/95 (2%) Query: 1454 ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAED 1513 +N EG V F CK+ + ++EW ++G + R +D + L I + D Sbjct: 5258 QNAREGDVVKFSCKVTGYPEP--EIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHAD 5315 Query: 1514 SGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548 SG+Y C N G S L T R + N Sbjct: 5316 SGMYKCTLKNNSGWASSSAELVVGGKTQRPRLSDN 5350 Score = 38.3 bits (85), Expect = 0.15 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%) Query: 3571 ENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLY 3630 E F C++ + +EW +G + + RV T D L I D+G+Y Sbjct: 5262 EGDVVKFSCKVTGYPEPE--IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMY 5319 Query: 3631 TCKATNRHGEATVSCKLQVKGR 3652 C N G A+ S +L V G+ Sbjct: 5320 KCTLKNNSGWASSSAELVVGGK 5341 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714 VEG+ V L V+ P++K W+K G L T L + + I S +++ SG Sbjct: 5455 VEGREVELSTVVKGLPRPSVK--WYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGR 5512 Query: 2715 YTCKATNLLGEA 2726 Y C+ATN G A Sbjct: 5513 YRCEATNSNGTA 5524 Score = 38.3 bits (85), Expect = 0.15 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 12/127 (9%) Query: 2907 EYPKPEWIIPIAA---EH-QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962 + P +W+ P +H ++EG G++ P +EWY + + + + R + Sbjct: 5535 QVPAEQWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVP--VVEWYRDDRPVTRDHRLRT 5592 Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022 SD V L L D+G++ C N G +S+++ N+ E P+ E L Sbjct: 5593 YSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASL------NVNEGYSKPEINEKL 5646 Query: 3023 EKIQNLE 3029 +KI+ E Sbjct: 5647 KKIEAFE 5653 Score = 38.3 bits (85), Expect = 0.15 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 2/88 (2%) Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636 AP T L++++I EG F + V VEWY +++P+ R ++ V Sbjct: 5543 APAFTAPLQHIDILEGDTTRFIGEITGVPVPV--VEWYRDDRPVTRDHRLRTYSDGRVVI 5600 Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTS 1664 L + D+G + C N LG +S Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASS 5628 Score = 38.3 bits (85), Expect = 0.15 Identities = 23/92 (25%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F PL+ + +EG F I G P +EW ++ + + R + + L Sbjct: 5544 PAFTAPLQHIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVIL 5601 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + NI D+G + C + G + A L+V Sbjct: 5602 LLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633 Score = 38.3 bits (85), Expect = 0.15 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%) Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKST-HDFSYVSLDITHT 2838 L I EG F+ V P +++W+ + RY ST SL I Sbjct: 5646 LKKIEAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKI 5703 Query: 2839 YEEDSGIYTCKATNSKGSATTSGSLRCTGDKN 2870 +ED G+Y C A N G T+ L G+K+ Sbjct: 5704 RQEDGGLYGCVAVNEYGETTSIVDLH-VGEKH 5734 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 3/94 (3%) Query: 770 PQFIRPLQDLGEL-QEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828 P+F D + ++G NA T +P V WYKDG + ++ + Sbjct: 5737 PEFAEEELDWSKTARKGENARIT--FTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQ 5794 Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 L I L +D G+Y A ++LG++ T +++V Sbjct: 5795 YLTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKV 5828 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 3/83 (3%) Query: 1724 ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGT 1782 E+ A F+ + G PK VEW + I +S + + D G +L +K + +D+G Sbjct: 4 ESGEARFDVTI--EGYPKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61 Query: 1783 YTCRAINELGEAVTSSTLFVQSK 1805 Y C A N+ G+ L V+ K Sbjct: 62 YKCVATNDAGQTSLRGDLSVKEK 84 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 4/85 (4%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVSL 2833 F+ + ++ E + + FE ++ P +EW+ + G R+ + + SL Sbjct: 535 FLRKVEDVTALETEQVWFEIPIQGYPRPI--VEWYRGTTRIKDGGRFTISESEENDMYSL 592 Query: 2834 DITHTYEEDSGIYTCKATNSKGSAT 2858 I EDSG Y C A+N G T Sbjct: 593 VIDEARTEDSGPYKCVASNDAGKTT 617 Score = 37.9 bits (84), Expect = 0.20 Identities = 26/109 (23%), Positives = 45/109 (41%), Gaps = 8/109 (7%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F+ L+ + EG F+ G P +++W ++ I+ S RF + + +L Sbjct: 1021 PTFMSKLEPIEITEGDD--FQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 1078 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745 + + D G Y C + G +KA T+ + PE LQ Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFGSVSSKA------DVTVLKKHLRPEVLQ 1121 Score = 37.9 bits (84), Expect = 0.20 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 5/126 (3%) Query: 3405 VRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLK 3464 V R D VEE K AP F + ++EG A ++ P+ V WY + + Sbjct: 1201 VVRADLEVEE-KNVAPSFHGRQGRLR-VKEGREASVYFEISGKPKPS--VTWYKDDVVIG 1256 Query: 3465 AGSRFRTFCDFGF-VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523 R G I PED G Y C A N+ G A T + V+ K+ +++ + Sbjct: 1257 DEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPE 1316 Query: 3524 LPKGME 3529 + + ++ Sbjct: 1317 IRQQLQ 1322 Score = 37.9 bits (84), Expect = 0.20 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 1/56 (1%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGY-VSMTISHVRDEDEGVYMCRASNLLG 2458 G P V W++++ +I D R + G TI R ED+G Y C A N +G Sbjct: 1240 GKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVG 1295 Score = 37.9 bits (84), Expect = 0.20 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 4/88 (4%) Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSD--FGFVTLDLVDVYERDSGIYTCKAYNKR 2992 V+ K P ++EWY + G R+ LT D G ++ + D+ D G Y A+N Sbjct: 1725 VKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDI 1784 Query: 2993 GEAFTSSTVYCTSKDNLIERTQHPKGTE 3020 G+ TS T K+ LI + TE Sbjct: 1785 GK--TSERAELTVKEKLIAPEFEGRETE 1810 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/67 (32%), Positives = 31/67 (46%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 PT I W+ + +PL R + L I + ED+G YTC+A N G+A S Sbjct: 2863 PTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFE 2922 Query: 2863 LRCTGDK 2869 + T K Sbjct: 2923 VDVTAPK 2929 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 4/85 (4%) Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF--TSIFRFGYISLDMLSLNI 703 V A+EG K+ F+TRI G P +EW + + S ++ G SL + + Sbjct: 3497 VQAVEGWKVQFQTRI--TGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTK 3554 Query: 704 QDSGEYTCRAVSATGVAETKAVLHV 728 D G Y C A ++ G + + L V Sbjct: 3555 DDIGTYKCLATNSAGSSACRINLDV 3579 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 943 VEWLKDGRPVEASSRITT--FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000 VEW + + R T + G +L I V + D+G Y A N +G+ATT A LT Sbjct: 4288 VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELT 4347 Query: 1001 IVTK 1004 + K Sbjct: 4348 VKGK 4351 Score = 37.9 bits (84), Expect = 0.20 Identities = 54/193 (27%), Positives = 87/193 (45%), Gaps = 25/193 (12%) Query: 1900 GF-AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ--SKES-IIRDSQ---HESAL 1952 GF +AL L V ++S E+ C+ + + +N Q S++S II S H+ A+ Sbjct: 4456 GFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWF-MNDQPVSRDSRIITSSDGPVHKLAI 4514 Query: 1953 EKIQYLEDDSRYK-RAVQDDSFVVE-----------KPQFGKPIKNAEVTEGHPVHLEAT 2000 K L+D YK AV D+ KP F + ++ EVT + Sbjct: 4515 TKAT-LQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLR--EVTTVFGGEASFS 4571 Query: 2001 LTPVNDPTMRVEWYCN-GRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059 + P ++ WY + R + +G RF + + L I +D+GTYMC +NAVG Sbjct: 4572 VRVKGFPRPKIVWYKDITRLINRG-RFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVG 4630 Query: 2060 EAVTTSSVKVDAK 2072 + S + V+A+ Sbjct: 4631 KETCRSQLVVEAE 4643 Score = 37.9 bits (84), Expect = 0.20 Identities = 31/124 (25%), Positives = 52/124 (41%), Gaps = 6/124 (4%) Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962 VP+ ++ P ++I + + EG+ LE VE P K+EW+ N K ++ + Sbjct: 4745 VPEEDWSAPSFVIELTPT-TVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRS 4801 Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS---STVYCTSKDNLIERTQHPKGT 3019 D + L + D+G+Y C N G A + S +K + E+ Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAV 4861 Query: 3020 EGLE 3023 EG E Sbjct: 4862 EGTE 4865 Score = 37.9 bits (84), Expect = 0.20 Identities = 18/73 (24%), Positives = 35/73 (47%) Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 ++ K+ P +EWY L G +++++ G +L + V + D+G Y A N+ G Sbjct: 5072 EIHVKSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAG 5131 Query: 2994 EAFTSSTVYCTSK 3006 + + + V K Sbjct: 5132 SSTSRAEVVVKDK 5144 Score = 37.9 bits (84), Expect = 0.20 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 4/118 (3%) Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314 ++ +K+ + Q Q P + + P F+ Q+ EG F ++ +P+ Sbjct: 5223 EATSKLGNTSAKFDVQIQAPEA-APKAPAFLKQLLPQNAR-EGDVVKFSCKVTGYPEPE- 5279 Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 +EW +G + R T++D L I +SG Y+C N G S+ A L Sbjct: 5280 -IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAEL 5336 Score = 37.9 bits (84), Expect = 0.20 Identities = 59/237 (24%), Positives = 90/237 (37%), Gaps = 46/237 (19%) Query: 3690 EKPNPPRFTV-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748 EK P F E + + EG V V+ G P + W+ G+ T S+ T++ Sbjct: 5436 EKTVAPEFPDRETLEQVVGVEGREVELSTVVK--GLPRPSVKWYKEGKLLHT-SKALTVS 5492 Query: 3749 DFGFIALDIDYIYARDA-----GEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803 G D Y++ A G Y C ATN G+A RD VL Q Sbjct: 5493 TSG----DTHYVWIPSAKHEHSGRYRCEATNSNGTA----------HRDFVLNIQ----- 5533 Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863 + P E+ + P F ++ + E + RF + P + Sbjct: 5534 -------------AQVPAEQWVA---PAFTAPLQHIDILEGDTTRFIGEITGVPVPV--V 5575 Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920 EWYR+ + + HR RT D V L + D+G + C ND G + A+++ Sbjct: 5576 EWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLN 5632 Score = 37.5 bits (83), Expect = 0.26 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-GYVALDILYTYAEDSGT 2181 E A F+ +E P T++W+ KI + +++ D G +L I +D+G Sbjct: 4 ESGEARFDVTIEGYPKP--TVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61 Query: 2182 YMCKATNKLGE 2192 Y C ATN G+ Sbjct: 62 YKCVATNDAGQ 72 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 2/72 (2%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 ++ EG+ ++L+ + K P+ + WY +GK L + L S L + DS Sbjct: 99 EVFEGESVNLDLTITGKPKPE--VVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDS 156 Query: 2982 GIYTCKAYNKRG 2993 G Y C+A NK G Sbjct: 157 GKYKCEAKNKIG 168 Score = 37.5 bits (83), Expect = 0.26 Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 7/122 (5%) Query: 1437 DESVTIKPRF--VTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494 D +V +K + VT + V EG+ F C + + W+K+GQP+ R + Sbjct: 175 DVNVKVKGKAPTVTSELKPDKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVK 232 Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR---STTDIVRSTQNEAG 1551 D L I D+ +D G Y N +G+ + L + ++VR +N Sbjct: 233 DSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVES 292 Query: 1552 LE 1553 +E Sbjct: 293 VE 294 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 10/100 (10%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 +V +E D I+F+ V PT I W+ + + + R++ + ED Sbjct: 2343 VVVQESDAINFKVRVRGKPVPT--IVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAED 2400 Query: 2843 SGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKA 2882 +G YTC+A+N G +C+ D N++ D Q +A Sbjct: 2401 AGTYTCEASNKLG--------KCSRDFNLHVDVPKEQWEA 2432 Score = 37.5 bits (83), Expect = 0.26 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDLIAEDSGIYTCRAVNLVG 1526 + W+K+G+P+ R I G V L I++L ED+G YTC A N +G Sbjct: 2867 ITWYKDGEPLDDTRRI-DIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIG 2915 Score = 37.5 bits (83), Expect = 0.26 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%) Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDS 3490 N+ EG+ + + + P L+V WY +G+ L+ R L I PEDS Sbjct: 3598 NVPEGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDS 3655 Query: 3491 GEYLCRAYNNYGEAVTTASMK 3511 G Y C + G + T +K Sbjct: 3656 GLYKCEGVSTLGTSSKTFDVK 3676 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 3/97 (3%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P+ +++ V+GT+ R++ G +V WF I + R+ + D +L Sbjct: 3783 PRIIEKPRDVDAVDGTDAKFTVRVE--GFPQPKVTWFHESTKIVSRGRYEISRVGDLYSL 3840 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407 + V G Y C ATN G+ C L V K+D Sbjct: 3841 VIRGVEYLHVGTYKCIATNDAGKVTAHCHLDV-TKQD 3876 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F ++++ A F R+ G P+ ++ W ++ + R + L Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRV--KGFPRPKIVWYKDITRLINRGRFHISEEGDLYNL 4608 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 ++ V +DSGTY C N +G+ S L V+++ Sbjct: 4609 TIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAE 4643 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 3/97 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+ ++ D+ VEG E ++ P KVEWF + +L + RY Sbjct: 4849 PEVAEKMTDIDA-VEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTST 4905 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 L I C ++G Y+ + TN+ G NL +E Sbjct: 4906 LVIRNCTTNDTGPYKVIGTNECGIGGAVLNLIIHERE 4942 Score = 37.5 bits (83), Expect = 0.26 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 2/95 (2%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P T D E S+ FE + + VEW+ L G + + G L Sbjct: 5052 PVITRKIRDAQGEEGSNIRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSL 5109 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 I GV + D G Y ATN+ G +T ++ VK + Sbjct: 5110 TITGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDK 5144 Score = 37.5 bits (83), Expect = 0.26 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099 TQ+PR +K V G+ A FE V ++ + WY + + S +R + G Sbjct: 5342 TQRPRLSDNMKELFATVGGE-ARFE--VTMKATPKPKICWYKDEITLRSRDRYTMKEEDG 5398 Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGE 1126 L I V+ DSG Y VA N AG+ Sbjct: 5399 IYTLIIKEVQLSDSGTYKFVASNKAGK 5425 Score = 37.5 bits (83), Expect = 0.26 Identities = 29/115 (25%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+ +K + A GG+ FE ++ P KI W K+ ++ + R+T G +L Sbjct: 5345 PRLSDNMKELFATVGGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIYTL 5402 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751 + + + DSG Y A + G L V + T+ ETL+ + +E Sbjct: 5403 IIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK-TVAPEFPDRETLEQVVGVE 5456 Score = 37.1 bits (82), Expect = 0.35 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 4/100 (4%) Query: 1037 VKITQK-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095 VK+ K P LK +K+ EG+ F V + + WY +G+ I + R++ Sbjct: 178 VKVKGKAPTVTSELK-PDKVQEGEQYKFTCAVTGKPK--PVISWYKDGQPIKADRRVKDS 234 Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 D L I V+ +D G Y V N G +A + V Sbjct: 235 FDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEV 274 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 4/71 (5%) Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT--LDINSVVANDAG 2579 EG A +E + G P + EW+ + +++ SRF+ T D T L I+ + +D+G Sbjct: 294 EGSDAFFEVKFK--GYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSG 351 Query: 2580 LYMCKAINRAG 2590 Y C A N AG Sbjct: 352 AYQCIASNEAG 362 Score = 37.1 bits (82), Expect = 0.35 Identities = 36/126 (28%), Positives = 49/126 (38%), Gaps = 6/126 (4%) Query: 1965 KRAVQDDSFVVEK---PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021 K V+ D V EK P F V EG + ++ P V WY + + Sbjct: 1199 KTVVRADLEVEEKNVAPSFHGRQGRLRVKEGREASVYFEIS--GKPKPSVTWYKDDVVIG 1256 Query: 2022 QGHRFKTTYDFGY-VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL 2080 R Y G I A ED GTY C+A N VG A T + V+ K + + Sbjct: 1257 DEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPE 1316 Query: 2081 DEQRLK 2086 Q+L+ Sbjct: 1317 IRQQLQ 1322 Score = 37.1 bits (82), Expect = 0.35 Identities = 21/74 (28%), Positives = 32/74 (43%) Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721 +E R P + W+KNG L G ++ TL I +D+G Y C A N Sbjct: 1526 VEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARN 1585 Query: 2722 LLGEAVSTASIKIE 2735 +G A +++E Sbjct: 1586 DVGSAERLFEVQVE 1599 Score = 37.1 bits (82), Expect = 0.35 Identities = 20/94 (21%), Positives = 41/94 (43%), Gaps = 2/94 (2%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P+ +++A +TE L + DP+ EW + +PV+ +++D Sbjct: 1606 EAPKLTSQLRSARITESDDFELACDVKGTPDPSY--EWLKDDKPVKFDRHLSSSFDGKKC 1663 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 L+ D G+Y NA G +++++ + Sbjct: 1664 TLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDI 1697 Score = 37.1 bits (82), Expect = 0.35 Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 4/113 (3%) Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021 S Y A D KP+ + +K+AE E + + P VEWY + Sbjct: 1688 STYSSANLDIVKSKSKPEILETMKDAEGIETGKAKFDVKIKAY--PKAEVEWYHRSARIY 1745 Query: 2022 QGHRFKTTYDF--GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 G R+ T D G ++ I ED GTY A N +G+ + + V K Sbjct: 1746 DGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798 Score = 37.1 bits (82), Expect = 0.35 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 2/80 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG E V PT +EW+ + + G R++ T + Y +L I ++ + Y Sbjct: 2012 EGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAASY 2069 Query: 2847 TCKATNSKGSATTSGSLRCT 2866 C A N+ G T L T Sbjct: 2070 KCVAFNNAGRTTYRADLVIT 2089 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 4/88 (4%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF--GFV 1635 P+ T L +++ EG+ A F+ + T VEW+ + G R+ +N G Sbjct: 3031 PLITHKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEEQGKH 3088 Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVT 1663 +L + +D G Y C A N G+A T Sbjct: 3089 SLIVSDLNADDDGIYKCVAQNLAGKAST 3116 Score = 37.1 bits (82), Expect = 0.35 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 4/84 (4%) Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK--TYYDFGFVALDIIHATSADTG 1248 EGK + +E G P+ VEWF ++ G R++ + + G +L + + D G Sbjct: 3044 EGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDG 3101 Query: 1249 EYTVRAVNHLGSAHTSAIVRVIER 1272 Y A N G A T A++ VI R Sbjct: 3102 IYKCVAQNLAGKASTRAMLDVIAR 3125 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 3/95 (3%) Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337 SA P F + ++ + + E +SA F + P +++WF N + + R T D Sbjct: 4451 SALAPGFKSALRSLD-VTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDG 4507 Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 + L I +++G Y+C+A N G ++ A+L Sbjct: 4508 PVHKLAITKATLQDTGVYKCLAVNDNGSATSTADL 4542 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566 KP F + L + ++ G+ A + RV G P + WY + L RF + + Sbjct: 4550 KPTFVERLREVTTVFGGE-ASFSVRVK--GFPRPKIVWYKDITRLINRGRFHISEEGDLY 4606 Query: 2567 TLDINSVVANDAGLYMCKAINRAG 2590 L I +V +D+G YMC N G Sbjct: 4607 NLTIENVGRDDSGTYMCILSNAVG 4630 Score = 37.1 bits (82), Expect = 0.35 Identities = 15/27 (55%), Positives = 19/27 (70%) Query: 3625 RDAGLYTCKATNRHGEATVSCKLQVKG 3651 +D GLY C ATN HGEA++ L V+G Sbjct: 4717 KDGGLYKCVATNEHGEASMLFNLDVEG 4743 Score = 37.1 bits (82), Expect = 0.35 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 2/85 (2%) Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714 VEG V LE V P K+EWF++ V LT R + TL I + +D+G Sbjct: 4861 VEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCTTNDTGP 4918 Query: 2715 YTCKATNLLGEAVSTASIKIEDRHW 2739 Y TN G + ++ I +R + Sbjct: 4919 YKVIGTNECGIGGAVLNLIIHEREF 4943 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 2/98 (2%) Query: 4083 SIEKIREMEASWQVTPEQVVEESKARCPPVF-VSLPDAVTVEEGEWARFCCRVTGHPKPR 4141 S + + +A + +VV + K P V ++ +T+ G + G PKP Sbjct: 5121 SYKVVATNQAGSSTSRAEVVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIRGKPKPS 5180 Query: 4142 VMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTG 4178 V+W +GN I+ ++ G +YH I T+ G Sbjct: 5181 VVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAG 5218 Score = 37.1 bits (82), Expect = 0.35 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 8/101 (7%) Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984 EG V+ +V +P+ IEW +G +E R D TL + + DSG+Y Sbjct: 5262 EGDVVKFSCKVTGYPEPE--IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMY 5319 Query: 2985 TCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKI 3025 C N G A +S+ + K TQ P+ ++ ++++ Sbjct: 5320 KCTLKNNSGWASSSAELVVGGK------TQRPRLSDNMKEL 5354 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/112 (21%), Positives = 49/112 (43%), Gaps = 2/112 (1%) Query: 4092 ASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 + W + ++V K + P + ++ + GE ARF + PKP++ W + T+ Sbjct: 5327 SGWASSSAELVVGGKTQRPRLSDNMKELFATVGGE-ARFEVTMKATPKPKICWYKDEITL 5385 Query: 4152 VNGSRYKL-TYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202 + RY + DG+Y I + + D+G + + L+V+ + Sbjct: 5386 RSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK 5437 Score = 36.7 bits (81), Expect = 0.46 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162 TVE GE ARF + G+PKP V W N I + ++K+ D Sbjct: 2 TVESGE-ARFDVTIEGYPKPTVEWYQGKNKIGSSGKHKILED 42 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 6/76 (7%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRF--RTTHDFGFVTLDINSVV 2574 P E++EG+ + + + G P WY +G L+ ++T D F L I Sbjct: 97 PIEVFEGESVNLDLTIT--GKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF--LSIPKAT 152 Query: 2575 ANDAGLYMCKAINRAG 2590 ND+G Y C+A N+ G Sbjct: 153 PNDSGKYKCEAKNKIG 168 Score = 36.7 bits (81), Expect = 0.46 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 4/95 (4%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR--VKTINDFGFV 3615 PE D+ E A+F ++ +EW+ + G R +KT + Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAF--PKPEIEWYLGATKITDGGRFKIKTDKENCSY 1174 Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 IL I V DAG C ATN G+ V L+V+ Sbjct: 1175 ILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVE 1209 Score = 36.7 bits (81), Expect = 0.46 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 8/100 (8%) Query: 917 DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRI---TTFFNFGYVALTIKS 973 D + EGG A+F +++ +EW + R T N Y+ L I Sbjct: 1124 DDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSYI-LFIDD 1180 Query: 974 VTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013 V + DAG C A NA G+ A+L + K +A S H Sbjct: 1181 VKLDDAGTVKCSATNAAGKTVVRADLEVEEKN--VAPSFH 1218 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRF--RTTHDFGFVTLDINSVVANDAG 2579 EG A++ ++ P + EWY+ ++ G RF +T + L I+ V +DAG Sbjct: 1130 EGGKANFAVKIDAFPKPEI--EWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAG 1187 Query: 2580 LYMCKAINRAG 2590 C A N AG Sbjct: 1188 TVKCSATNAAG 1198 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 3/95 (3%) Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750 K P ++KD V EG F+ ++ G P+ I+W++ G R D Sbjct: 1407 KCTKPEVLEKMKDVKGV-EGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGRYKFSRDD 1463 Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 +L I + +D G Y C A+N+ G T A++ Sbjct: 1464 QKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAEL 1498 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 5/102 (4%) Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD- 1231 SKSKP ++ + + + GK + +++ P VEW+H + G R+ D Sbjct: 1700 SKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDE 1756 Query: 1232 -FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 G ++ I D G Y + A N +G A + V E+ Sbjct: 1757 EDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798 Score = 36.7 bits (81), Expect = 0.46 Identities = 19/67 (28%), Positives = 32/67 (47%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 P+ + WY N + R + T D L L D+ +D+G Y C A N G+AF ++ Sbjct: 1930 PEPSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAE 1989 Query: 3001 VYCTSKD 3007 + ++ Sbjct: 1990 MTVNKRE 1996 Score = 36.7 bits (81), Expect = 0.46 Identities = 20/59 (33%), Positives = 30/59 (50%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 + W+ +G+PL R+ + L I + DAG YTC+A NR G A S ++ V Sbjct: 2867 ITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925 Score = 36.7 bits (81), Expect = 0.46 Identities = 16/65 (24%), Positives = 36/65 (55%) Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 +P + W+++G+ L R+ L ++I L +D+G Y C+A + +G A+ + Sbjct: 3409 NPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRSC 3468 Query: 2731 SIKIE 2735 +++I+ Sbjct: 3469 TLEIK 3473 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Query: 3591 VEWFHNGKPLLTGSRVKTIN--DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ 3648 VEW+ L + K + G L + V + D G Y C ATN G + L Sbjct: 3519 VEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLD 3578 Query: 3649 VKGRQGIILEPQLPSH 3664 VK +Q P++P H Sbjct: 3579 VKDKQ---YAPEIPGH 3591 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/67 (32%), Positives = 28/67 (41%) Query: 3845 EGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYIC 3904 EG V K P+L + WY++G+LL R L I EDSG Y C Sbjct: 3601 EGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLYKC 3660 Query: 3905 RAVNDFG 3911 V+ G Sbjct: 3661 EGVSTLG 3667 Score = 36.7 bits (81), Expect = 0.46 Identities = 20/57 (35%), Positives = 27/57 (47%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794 G P VEW ++G + +N L Y L++ DSGTY A N+LG A Sbjct: 3906 GKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSA 3962 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 1/100 (1%) Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508 +P V W+ +G L SR L I P+D+G Y+C A + G + Sbjct: 4179 NPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSC 4238 Query: 3509 SMKVQGKR-NIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547 ++ V+ R E Q K + + A+EG+ +DT Sbjct: 4239 TLDVKAVRPRRGNEVQACKPQTSKMANVTAVEGWKVQLDT 4278 Score = 36.7 bits (81), Expect = 0.46 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 3/101 (2%) Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918 G A +E ++ P P ++ WY + L+S RY + G L I V DSG Y Sbjct: 5359 GGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYK 5416 Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959 A N G+ L V K ++ + LE++ +E Sbjct: 5417 FVASNKAGKTTFLGYLEVMEK-TVAPEFPDRETLEQVVGVE 5456 Score = 36.3 bits (80), Expect = 0.61 Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 3/100 (3%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E +PEF +K I +K G A LE G +V W KD P+ + I Sbjct: 624 VNEKVVQPEFDKEVKP-IEVKHGEEA--TTSLEIKGKPKPKVTWYKDLVPLLETRSIQLK 680 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 L I + T D G Y C A N G A S ++ + Sbjct: 681 SVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKV 720 Score = 36.3 bits (80), Expect = 0.61 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 7/123 (5%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF---TETNNFGF 1634 P + +V EG +A+F ++ ++EWY + G RF T+ N + Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSY 1174 Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDT 1694 + L I +D+GT C A NA G+ V V K +G L R+ + + Sbjct: 1175 I-LFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKNVAPSFHGRQGRL-RVKEGREA 1232 Query: 1695 SKY 1697 S Y Sbjct: 1233 SVY 1235 Score = 36.3 bits (80), Expect = 0.61 Identities = 19/74 (25%), Positives = 32/74 (43%) Query: 1997 LEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056 LE + P+ V WY + R + G + + + A D G+Y C+A N Sbjct: 1821 LEVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKN 1880 Query: 2057 AVGEAVTTSSVKVD 2070 VG A +V+++ Sbjct: 1881 RVGSATRNFNVEIE 1894 Score = 36.3 bits (80), Expect = 0.61 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%) Query: 773 IRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNI 832 I+ + E+ EG A E +++ V PT VEWY + R Y +L+I Sbjct: 2001 IKEVSKTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSI 2058 Query: 833 MHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 + + A SY A N G A + + R Sbjct: 2059 RDVGDQAAASYKCVAFNNAGRTTYRADLVITER 2091 Score = 36.3 bits (80), Expect = 0.61 Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 15/203 (7%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 +AP F ++ + + E + G P ++W+++ P+ +R+ D Sbjct: 2431 EAPSFKSQLQPVILEEGGTGVLVGEV--AGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTC 2488 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828 + + D G Y C N+ GEA +S L ++ ++ E + A I + DS Sbjct: 2489 KVIFREALIGDGGMYECIIKNQCGEA-SSKALVGVNRGTVGPEIIEKPAGLVIVEGNDS- 2546 Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888 R DV + + P + G +L++G + RIE P+ + ++ Q Sbjct: 2547 ----RFDVRIRGHPTPE-VEWFYGSERLTDG----VKYRIESNPEIGLYSLVVSKVQLDQ 2597 Query: 1889 SGH-RYRTSNDFGFA-ALDILTV 1909 +GH R SN+ G A AL LTV Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTV 2620 Score = 36.3 bits (80), Expect = 0.61 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Query: 650 EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEY 709 EG +I+ + I+ P +++ W K+G+ ++ + R R + L + S +DSG Y Sbjct: 3601 EGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLY 3658 Query: 710 TCRAVSATGVA 720 C VS G + Sbjct: 3659 KCEGVSTLGTS 3669 Score = 36.3 bits (80), Expect = 0.61 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 4/102 (3%) Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737 T H ++T +D P E+ + I V EG V V G P ++WF +G+ Sbjct: 3865 TAHCHLDVTKQDFAPIVAGS--EMPEPIVVREGCEVSMMANVR--GKPAPTVEWFKDGQL 3920 Query: 3738 FATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779 + + +H + LD+ D+G Y ATN GSA Sbjct: 3921 LSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSA 3962 Score = 36.3 bits (80), Expect = 0.61 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 2945 IEWYFNGKVLEQGSRFKLT--SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997 +EW+ + + G R+K D G +L + DV DSG Y A N GEA T Sbjct: 4288 VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATT 4342 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V KP F +++ ++ GG A F R++ G ++ W KD + R Sbjct: 4544 VSHCRMKPTFVERLREVTTVF-GGEASFSVRVK--GFPRPKIVWYKDITRLINRGRFHIS 4600 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 LTI++V D+G Y C NA+G+ T + L + Sbjct: 4601 EEGDLYNLTIENVGRDDSGTYMCILSNAVGKETCRSQLVV 4640 Score = 36.3 bits (80), Expect = 0.61 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 3/84 (3%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 +PV T+ +++ +EG F+ + P VEW+R + + + G Sbjct: 5051 KPVITRKIRDAQG-EEGSNIRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAY 5107 Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458 S+TI+ V+ +D G Y A+N G Sbjct: 5108 SLTITGVQKDDTGSYKVVATNQAG 5131 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 6/87 (6%) Query: 79 KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS-LLIKQIG 137 K AR +G NA+ + GNP P V W + L + MR GD+ L I + Sbjct: 5748 KTAR--KGENARITFTVSGNPRPDVVWYKDGMLLFDTTHVDMR---SRGDIQYLTIFGLT 5802 Query: 138 PGDEGEYTCTARNQYGEAICSVYIQPE 164 D G Y C A+++ G++ + ++ E Sbjct: 5803 HDDTGTYVCEAQSRLGKSFRTYALKVE 5829 Score = 35.9 bits (79), Expect = 0.80 Identities = 22/102 (21%), Positives = 38/102 (37%), Gaps = 2/102 (1%) Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161 V E + P + + D ++ GE + C VTG P P V W +G + R ++ Sbjct: 722 VAEPQGETPTITTEMTDIQAID-GEDCKLICHVTGEPNPEVEWFKDGKPLKANHRLVPSF 780 Query: 4162 -DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202 + M + D G+ + + +KV R Sbjct: 781 EERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822 Score = 35.9 bits (79), Expect = 0.80 Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 10/109 (9%) Query: 1033 TEEEVKITQK---PRFLGPLKGTNKIVEGQSAHFEA--RVEPQSDLTMTVEWYFNGKQIT 1087 T E+K+ +K P F K T ++GQ + R +P+ ++ W +G+++ Sbjct: 909 TRAELKVNEKHFAPEF-EDWKDTIDALDGQDVNISTWVRGKPKPEIV----WLKDGEELR 963 Query: 1088 SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 + +Q L + V ED+G+YT A+N AG ++TVE Sbjct: 964 NTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVE 1012 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 4/90 (4%) Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGFIALDIDYI 3760 D++ EGG +F +++ P I+W+ G R + T + L ID + Sbjct: 1124 DDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSYILFIDDV 1181 Query: 3761 YARDAGEYTCRATNKWGSATTTAKITCSAK 3790 DAG C ATN G A + K Sbjct: 1182 KLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 2/102 (1%) Query: 3845 EGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF-VSLDILYVYAEDSGEYI 3903 EG E PK + WY++ ++ R +Y G I ED G Y Sbjct: 1228 EGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYK 1287 Query: 3904 CRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945 C A ND G F I + ++++ ++ R ++E +T+ Sbjct: 1288 CEARNDVGTAFETFPIDVEVKQEVMIAPEI-RQQLQAEDVTE 1328 Score = 35.9 bits (79), Expect = 0.80 Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 8/115 (6%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+ L+S E FE + G P EWLK+ + ++ +S F +L Sbjct: 1608 PKLTSQLRSARITESDD--FELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTL 1665 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751 + + + D G YT +A G + A L + ++ PE L+ ++ E Sbjct: 1666 NFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIV------KSKSKPEILETMKDAE 1714 Score = 35.9 bits (79), Expect = 0.80 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 3/95 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +AP F + L+ L EG L +V + P I+W K+ + G R++ FD Sbjct: 2431 EAPSFKSQLQPVI-LEEGGTGVLVGEVAGKPLPT--IQWMKDDYPVLFGHRVRPQFDGRT 2487 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 + D G+Y C N GEA S A + + Sbjct: 2488 CKVIFREALIGDGGMYECIIKNQCGEASSKALVGV 2522 Score = 35.9 bits (79), Expect = 0.80 Identities = 16/49 (32%), Positives = 23/49 (46%) Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 ++W K+ PV GHR RP D + + + D G+Y C N G Sbjct: 2464 IQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCG 2512 Score = 35.9 bits (79), Expect = 0.80 Identities = 17/66 (25%), Positives = 35/66 (53%) Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 +P + W+K+G+ L +R + +I + +D+G Y C+A N LG + + Sbjct: 2655 NPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSC 2714 Query: 2731 SIKIED 2736 +I+I++ Sbjct: 2715 TIEIKE 2720 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 2/77 (2%) Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI-NDFGFVI-LEIGGVYQRDAGLYTCKATN 3636 C ++ + +EWF L G + K + +D G + L + V DAG Y C Sbjct: 2754 CDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHT 2813 Query: 3637 RHGEATVSCKLQVKGRQ 3653 G+ T+ +L +K +Q Sbjct: 2814 PAGQTTIRGELHIKEKQ 2830 Score = 35.9 bits (79), Expect = 0.80 Identities = 16/56 (28%), Positives = 28/56 (50%), Gaps = 2/56 (3%) Query: 2398 CRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFGYVSMTISHVRDEDEGVYMC 2451 C ++ + +EWFR ++ D + I K+ D +S+ + +V ED G Y C Sbjct: 2754 CDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRC 2809 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Query: 1586 NVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMSCL 1643 +V+ EG + F+ R+ VEWY L ++ +T G +L + Sbjct: 3496 DVQAVEGWKVQFQTRITGYPYP--HVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVT 3553 Query: 1644 PEDSGTYTCRAINALGEA 1661 +D GTY C A N+ G + Sbjct: 3554 KDDIGTYKCLATNSAGSS 3571 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/101 (20%), Positives = 44/101 (43%), Gaps = 2/101 (1%) Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 R + ++D++ P E + ++VPEG ++ D ++ P + + W+ +G Sbjct: 3574 RINLDVKDKQYAPEIPGHEDRQELNVPEGQEINMDVVIK--SKPRLEVSWYKDGELLQDT 3631 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 R+ + L I D+G Y C + G+++ T Sbjct: 3632 KRIDIRSRGDHYYLVIPSAAPEDSGLYKCEGVSTLGTSSKT 3672 Score = 35.9 bits (79), Expect = 0.80 Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383 EG ++++ ++ + V W+ +G+ ++ R D+ L + S PEDSG+Y Sbjct: 3601 EGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLY 3658 Query: 1384 TCQATNQLG 1392 C+ + LG Sbjct: 3659 KCEGVSTLG 3667 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 PKF++ + + + EG SA ++ +P VEWF + + + + R R+ Sbjct: 3687 PKFLSHLNSLD-VDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCT 3743 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKA 3370 L ++ G Y C ATN+ G S+ A Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSA 3772 Score = 35.9 bits (79), Expect = 0.80 Identities = 17/59 (28%), Positives = 29/59 (49%) Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAF 2996 + P +EW+ +G++L + L + + LDL+ + DSG Y A N G A+ Sbjct: 3905 RGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAY 3963 Score = 35.9 bits (79), Expect = 0.80 Identities = 18/65 (27%), Positives = 30/65 (46%) Query: 2272 PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS 2331 P +E++ +G+ L + H+ Y +LD+ D+G Y A N LG + Sbjct: 3908 PAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFN 3967 Query: 2332 MTVTA 2336 + VTA Sbjct: 3968 LNVTA 3972 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 3/84 (3%) Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET 722 +G+P + W K+G + +SR R L++ L D+G Y C A S G Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236 Query: 723 KAVLH---VTPRATIERTSQHPET 743 L V PR E + P+T Sbjct: 4237 SCTLDVKAVRPRRGNEVQACKPQT 4260 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 3/85 (3%) Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234 +KP + +++ V EG + LE + G P +VEWF + +T R+ Sbjct: 4847 TKPEVAEKMTDIDAV-EGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDT 4903 Query: 1235 VALDIIHATSADTGEYTVRAVNHLG 1259 L I + T+ DTG Y V N G Sbjct: 4904 STLVIRNCTTNDTGPYKVIGTNECG 4928 Score = 35.9 bits (79), Expect = 0.80 Identities = 17/61 (27%), Positives = 31/61 (50%) Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997 + +P ++ WY +G +L +R S L++ + D+G Y C+A +K G+ F Sbjct: 4971 RGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFR 5030 Query: 2998 S 2998 S Sbjct: 5031 S 5031 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 7/79 (8%) Query: 2119 ENLKE-----GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILY 2173 +N+KE G A FE ++ P + W+ + +R+ RY + G L I Sbjct: 5349 DNMKELFATVGGEARFEVTMKATPKPKIC--WYKDEITLRSRDRYTMKEEDGIYTLIIKE 5406 Query: 2174 TYAEDSGTYMCKATNKLGE 2192 DSGTY A+NK G+ Sbjct: 5407 VQLSDSGTYKFVASNKAGK 5425 Score = 35.9 bits (79), Expect = 0.80 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 7/128 (5%) Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT--TMHDF 1765 T AP F +V + E + G P+ V+W + G + S LT T D Sbjct: 5438 TVAPEFPDRETLEQVVGVEGREVELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDT 5497 Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK--ASLQLESQHESALQKIQQ 1823 YV + E SG Y C A N G A L +Q++ A + + LQ I Sbjct: 5498 HYVWIPS--AKHEHSGRYRCEATNSNGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDI 5555 Query: 1824 LE-DSSRY 1830 LE D++R+ Sbjct: 5556 LEGDTTRF 5563 Score = 35.9 bits (79), Expect = 0.80 Identities = 44/187 (23%), Positives = 70/187 (37%), Gaps = 31/187 (16%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXX 2463 G P V+W++ KL+ S +T + + I + E G Y C A+N G Sbjct: 5468 GLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEATNSNG----- 5522 Query: 2464 XXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523 T H + + IQ ++ P ++ P FT L ++ EG Sbjct: 5523 --------------TAHRDFVLNIQ---------AQVPAEQWVAPAFTAPLQH-IDILEG 5558 Query: 2524 QHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583 + + V P + EWY + + R RT D V L + +DAG++ C Sbjct: 5559 DTTRFIGEITGVPVPVV--EWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKC 5616 Query: 2584 KAINRAG 2590 N G Sbjct: 5617 VLRNDLG 5623 Score = 35.5 bits (78), Expect = 1.1 Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 P +EW++ + + + K D G +L I L DD+G Y C ATN G+ Sbjct: 18 PKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRG 77 Query: 2731 SIKIEDR 2737 + ++++ Sbjct: 78 DLSVKEK 84 Score = 35.5 bits (78), Expect = 1.1 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 3/84 (3%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL-VTLSINSLRNDD 2711 ++ EG+ + ++ + P+ + W+K+ V + R + G +I R +D Sbjct: 1225 RVKEGREASVYFEISGKPKPS--VTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPED 1282 Query: 2712 SGIYTCKATNLLGEAVSTASIKIE 2735 G Y C+A N +G A T I +E Sbjct: 1283 KGTYKCEARNDVGTAFETFPIDVE 1306 Score = 35.5 bits (78), Expect = 1.1 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 ++EGQ A + + P+ VEW++ + L+ +I G + I +D G Sbjct: 2107 VREGQNAITNMTIR--ARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAG 2164 Query: 2448 VYMCRASNLLG 2458 Y+C+A+N +G Sbjct: 2165 TYICKATNSIG 2175 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 4/85 (4%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR--TVYDMGFV 3887 P+ I + + E RF+ R+ P+ +EW+ + L G +YR + ++G Sbjct: 2529 PEIIEKPAGLVIVEGNDSRFDVRIRGHPTPE--VEWFYGSERLTDGVKYRIESNPEIGLY 2586 Query: 3888 SLDILYVYAEDSGEYICRAVNDFGE 3912 SL + V + +G Y A N+ G+ Sbjct: 2587 SLVVSKVQLDQTGHYRIVASNEHGK 2611 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 4/84 (4%) Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT--ASSRITSIFNFGYVSLNIMHLRAEDAG 841 EG ++ F+ ++ PT VEW+ +T RI S G SL + ++ + G Sbjct: 2542 EGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTG 2599 Query: 842 SYTVRAVNKLGEAISTASIRVAAR 865 Y + A N+ G+A + + V R Sbjct: 2600 HYRIVASNEHGKAQALLDLTVNER 2623 Score = 35.5 bits (78), Expect = 1.1 Identities = 19/56 (33%), Positives = 27/56 (48%) Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 +G+P V W+++ L+ D+SR I V ED G Y+C A N LG Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLG 2708 Score = 35.5 bits (78), Expect = 1.1 Identities = 21/65 (32%), Positives = 28/65 (43%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 V WY + L SR + +I PED+GTY C A N LG + S + Sbjct: 2660 VTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEIK 2719 Query: 1671 SKKSI 1675 KS+ Sbjct: 2720 EPKSV 2724 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 3/96 (3%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P F +++ + GG F RV+ G P +I W+ + R H + Sbjct: 4551 PTFVERLRE-VTTVFGGEASFSVRVK--GFPRPKIVWYKDITRLINRGRFHISEEGDLYN 4607 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 L I+ + D+G Y C +N G T +++ A+ Sbjct: 4608 LTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAE 4643 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 2/90 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F+ +++ T F RV K P+ +I WY++ L + R+ + +L Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRV--KGFPRPKIVWYKDITRLINRGRFHISEEGDLYNL 4608 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 I V +DSG Y+C N G++ ++ + Sbjct: 4609 TIENVGRDDSGTYMCILSNAVGKETCRSQL 4638 Score = 35.5 bits (78), Expect = 1.1 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 8/129 (6%) Query: 2779 HLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHT 2838 ++ + G FE ++ + P KI W+ + L S RY + +L I Sbjct: 5350 NMKELFATVGGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIYTLIIKEV 5407 Query: 2839 YEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI---YFDTQHPQGKAGLEAVEQAEEARL 2895 DSG Y A+N G T G L +K + + D + + G+E + E + + Sbjct: 5408 QLSDSGTYKFVASNKAGKTTFLGYLEVM-EKTVAPEFPDRETLEQVVGVEG-REVELSTV 5465 Query: 2896 AKG-RRPSV 2903 KG RPSV Sbjct: 5466 VKGLPRPSV 5474 Score = 35.5 bits (78), Expect = 1.1 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 2523 GQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYM 2582 G A +E V P + WY + + L+ R+ + G TL I V +D+G Y Sbjct: 5359 GGEARFE--VTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYK 5416 Query: 2583 CKAINRAG 2590 A N+AG Sbjct: 5417 FVASNKAG 5424 Score = 35.5 bits (78), Expect = 1.1 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%) Query: 2941 PDLKIEWYFNGKVLEQGSRFK--LTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 P +++WY + +R+ LTSD G +L + + + D G+Y C A N+ GE Sbjct: 5667 PPPRVDWYRGTTKITDCNRYSSTLTSD-GMASLTIRKIRQEDGGLYGCVAVNEYGE 5721 Score = 35.5 bits (78), Expect = 1.1 Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 10/149 (6%) Query: 1797 SSTLFVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQ-APRFITQ-LNG 1852 SSTL ASL + Q + L + + D+ V P F + L+ Sbjct: 5687 SSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEKHYGPEFAEEELDW 5746 Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL-QSGH-RYRTSNDFGFAALDILTVY 1910 +G++A + P P+ V WY +G +L + H R+ D + L I + Sbjct: 5747 SKTARKGENARITFTVSGNPRPD--VVWYKDGMLLFDTTHVDMRSRGDIQY--LTIFGLT 5802 Query: 1911 GEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 +D+G Y C+A + LG++ + L V+ + Sbjct: 5803 HDDTGTYVCEAQSRLGKSFRTYALKVEEQ 5831 Score = 35.5 bits (78), Expect = 1.1 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 3/100 (3%) Query: 3415 EKGKAPVFTVP-LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 EK P F L + R+GENA T + +P V WY +G L + Sbjct: 5732 EKHYGPEFAEEELDWSKTARKGENARIT--FTVSGNPRPDVVWYKDGMLLFDTTHVDMRS 5789 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 L I +D+G Y+C A + G++ T ++KV+ Sbjct: 5790 RGDIQYLTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKVE 5829 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 4/98 (4%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV-QQGH-RFKTTYDFGYV 2035 P+F + + T + T T +P V WY +G + H ++ D Y Sbjct: 5737 PEFAEEELDWSKTARKGENARITFTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQY- 5795 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 L I +DTGTY+C+A + +G++ T ++KV+ ++ Sbjct: 5796 -LTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKVEEQA 5832 Score = 35.1 bits (77), Expect = 1.4 Identities = 33/157 (21%), Positives = 60/157 (38%), Gaps = 8/157 (5%) Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQI----QDVTKLVEGQ 3298 GK + ++ L D + + + Q S + + QI Q+ ++ EG+ Sbjct: 45 GKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGE 104 Query: 3299 SAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECV 3358 S + + + P+ V W+ +GK L L I +SG+Y+C Sbjct: 105 SVNLDLTITGKPKPE--VVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCE 162 Query: 3359 ATNKLGRDST--KANLKCTSKENLILDSQLPRGMEGG 3393 A NK+G + N+K K + P ++ G Sbjct: 163 AKNKIGTSARDFDVNVKVKGKAPTVTSELKPDKVQEG 199 Score = 35.1 bits (77), Expect = 1.4 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 6/106 (5%) Query: 1704 DEVITQ---APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760 D VIT+ AP F + R+A + + + P VEW + + + ++ Sbjct: 2085 DLVITEREYAPEFE-DFDEKRIAVREGQNAITNMTIRARPSPDVEWYKGDTLLMSDRKID 2143 Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806 G L ++ +D+GTY C+A N +G TS + V +A Sbjct: 2144 LKTIGGLYYLEIRKATLDDAGTYICKATNSIGS--TSRRIIVDVEA 2187 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 2518 SELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAND 2577 ++ +E A EA V V P+ EW++ +L G R+R TL I+++ D Sbjct: 3294 TDSFECSEARLEAHVAGVPRPT--VEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMED 3351 Query: 2578 AGLYMCKAINRAG 2590 G Y A N G Sbjct: 3352 TGPYKIIATNEHG 3364 Score = 35.1 bits (77), Expect = 1.4 Identities = 31/108 (28%), Positives = 50/108 (46%), Gaps = 8/108 (7%) Query: 1740 PKLRVEWLRNGVPIEASNR--LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 PK +V W ++G+ +E S R L ++ + YV + + EDSG Y C +E Sbjct: 4384 PK-QVIWYKDGIRLEDSRRVNLRSVGERYYVVVPS--ASFEDSGIYKCETTSEKETTSQL 4440 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPR 1845 + ++ L +SAL+ + ED S R EV+ + APR Sbjct: 4441 FDIHIEDVCKSALAPGFKSALRSLDVTEDESAEFR---CEVSGSPAPR 4485 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 3/95 (3%) Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101 KP F+ L+ + G+ A F RV+ + WY + ++ + R + Sbjct: 4550 KPTFVERLREVTTVFGGE-ASFSVRVKGFP--RPKIVWYKDITRLINRGRFHISEEGDLY 4606 Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 L I +V +DSG Y + NA G+ + + VE Sbjct: 4607 NLTIENVGRDDSGTYMCILSNAVGKETCRSQLVVE 4641 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 3/89 (3%) Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561 +R KP + +T + EG E V+ G P + EW+ + V+L R+ + Sbjct: 4843 NRALTKPEVAEKMTDIDAV-EGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISE 4899 Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590 TL I + ND G Y N G Sbjct: 4900 TEDTSTLVIRNCTTNDTGPYKVIGTNECG 4928 Score = 35.1 bits (77), Expect = 1.4 Identities = 18/74 (24%), Positives = 36/74 (48%) Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721 L V R P + W+K+G + T ++ + L I +++ +G Y+C+AT+ Sbjct: 5167 LNLNVTIRGKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEATS 5226 Query: 2722 LLGEAVSTASIKIE 2735 LG + ++I+ Sbjct: 5227 KLGNTSAKFDVQIQ 5240 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 4/84 (4%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT-KTHDFGYV 2434 P + Q + EG++ + D + G P +V W+++ K + + I K+ D Y Sbjct: 88 PQIKEKEQEPIEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF 145 Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458 ++I D G Y C A N +G Sbjct: 146 -LSIPKATPNDSGKYKCEAKNKIG 168 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/68 (29%), Positives = 27/68 (39%) Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264 G P +EWF + G RF + +L I D G Y A N G T Sbjct: 851 GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTR 910 Query: 1265 AIVRVIER 1272 A ++V E+ Sbjct: 911 AELKVNEK 918 Score = 34.7 bits (76), Expect = 1.9 Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 4/108 (3%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E P F + ++ +KEG A E G V W KD + R Sbjct: 1208 VEEKNVAPSFHGR-QGRLRVKEGREA--SVYFEISGKPKPSVTWYKDDVVIGDEDRNVDI 1264 Query: 962 FNFGY-VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008 ++ G TIK D G Y C A N +G A + + + K++++ Sbjct: 1265 YSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVM 1312 Score = 34.7 bits (76), Expect = 1.9 Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 5/116 (4%) Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297 K + P + +++ V EG A F ++ P+ IE+Y+ ++ R+ + D Sbjct: 1407 KCTKPEVLEKMKDVKGV-EGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDD 1463 Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQRPEGLE 2351 SL I+ +D G Y A N G T + V + I E Q E LE Sbjct: 1464 QKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKERDYAPIFEEKQFLEPLE 1519 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 6/96 (6%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV---KTINDFGF 3614 PEF +++ + E S V W+ + + LL G + K N + F Sbjct: 1802 PEFEGRETEVPFRAKEKSDLEVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRF 1861 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 + + DAG Y C+A NR G AT + ++++ Sbjct: 1862 TVFNVSA---GDAGSYRCEAKNRVGSATRNFNVEIE 1894 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 2/76 (2%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 I +EG N + P +EW+ + L S + L+I +D Sbjct: 2105 IAVREGQNAITNMTIRARPSPD--VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDD 2162 Query: 2843 SGIYTCKATNSKGSAT 2858 +G Y CKATNS GS + Sbjct: 2163 AGTYICKATNSIGSTS 2178 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%) Query: 921 IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVE--ASSRITTFFNFGYVALTIKSVTVHD 978 I EG + F+ R+ G T VEW + RI + G +L + V + Sbjct: 2540 IVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597 Query: 979 AGHYTCRAYNAIGQATTSANLTI 1001 GHY A N G+A +LT+ Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTV 2620 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167 +P F+ L + + G+ A F RV+ P + W+ + ++ R+ + + Sbjct: 4550 KPTFVERLREVTTVFGGE-ASFSVRVKGFPRPKIV--WYKDITRLINRGRFHISEEGDLY 4606 Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197 L I +DSGTYMC +N +G+ TC Sbjct: 4607 NLTIENVGRDDSGTYMCILSNAVGK--ETC 4634 Score = 34.7 bits (76), Expect = 1.9 Identities = 30/138 (21%), Positives = 53/138 (38%), Gaps = 3/138 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F+ L + G F V+ P KI W+ + L + R+ + + +L I Sbjct: 4553 FVERLREVTTVFGGEASFSVRVKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYNLTI 4610 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI-YFDTQHPQGKAGLEAVEQAEEAR 2894 + +DSG Y C +N+ G T L ++ +F QG + + +E Sbjct: 4611 ENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEEFAPFFPEDEGQGAVPVVTRQDSEVEL 4670 Query: 2895 LAKGRRPSVPDTEYPKPE 2912 A R P+ + K + Sbjct: 4671 GAVVRGSPKPEVAWYKDD 4688 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 2/82 (2%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P M DI E E +I G P +VEW R+ V + ++R T L Sbjct: 4849 PEVAEKMTDIDAVEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTL 4906 Query: 1771 NMKYVNPEDSGTYTCRAINELG 1792 ++ D+G Y NE G Sbjct: 4907 VIRNCTTNDTGPYKVIGTNECG 4928 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G PK V W ++G I S + L + + E +GTY+C A ++LG TS Sbjct: 5175 GKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGN--TS 5232 Query: 1798 STLFVQSKA 1806 + VQ +A Sbjct: 5233 AKFDVQIQA 5241 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 2/65 (3%) Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907 RFE V K PK +I WY++ L S RY + G +L I V DSG Y A Sbjct: 5363 RFE--VTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVAS 5420 Query: 3908 NDFGE 3912 N G+ Sbjct: 5421 NKAGK 5425 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 6/73 (8%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL--PSGTRYKSTHDFSYVSLDITHTYEEDSG 2844 EG++++ + + P ++ W+ + KPL KST D SY L I DSG Sbjct: 102 EGESVNLDLTITGKPKP--EVVWYKDGKPLRKTKSIDLKSTDD-SYF-LSIPKATPNDSG 157 Query: 2845 IYTCKATNSKGSA 2857 Y C+A N G++ Sbjct: 158 KYKCEAKNKIGTS 170 Score = 34.3 bits (75), Expect = 2.5 Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 5/109 (4%) Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022 DL K P V ++++ S VE FE + G P K EWF + K + +RF Sbjct: 271 DLEVTPKPAKPEVVRKMENVES-VEGSDAFFEVKFK--GYPIPKREWFHDSKKIEPSSRF 327 Query: 4023 TPIYDFGYVAMNF--GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069 D + + +DSG Y C A+N G +A +K KP Sbjct: 328 KITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKVKNKP 376 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 9/91 (9%) Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC- 3473 EK AP F I+ L +G++ + + P ++ W +G+ L+ + C Sbjct: 917 EKHFAPEFEDWKDTIDAL-DGQDVNISTWVRGKPKP--EIVWLKDGEELRNTMHVQIKCY 973 Query: 3474 -DF-GFVILEISPTYPEDSGEYLCRAYNNYG 3502 D G V+ ++SP ED+G Y CRA NN G Sbjct: 974 GDLHGLVLYKVSP---EDAGMYTCRAKNNAG 1001 Score = 34.3 bits (75), Expect = 2.5 Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 6/105 (5%) Query: 3547 TLTPEA--ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604 T+T EA + G+ P F + + ++E C + V+WF + + Sbjct: 1008 TITVEALQKKGDTPTFMSKLEPIEITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSR 1065 Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 R K D L + D G+Y C TN G +VS K V Sbjct: 1066 RFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFG--SVSSKADV 1108 Score = 34.3 bits (75), Expect = 2.5 Identities = 19/85 (22%), Positives = 36/85 (42%), Gaps = 2/85 (2%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 ++ EG L V + P+ ++W+ + +++ RFK + D L + + D Sbjct: 1031 EITEGDDFQLSCNVTGRPQPE--VQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDDD 1088 Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSK 3006 G+Y C N G + + V K Sbjct: 1089 GVYKCVVTNNFGSVSSKADVTVLKK 1113 Score = 34.3 bits (75), Expect = 2.5 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 8/102 (7%) Query: 1043 PRFLGPLKGTNKIVEGQSA--HFEARVEPQSDLTMTVEWYFNGKQITSANR-IQTYHDFG 1099 P F G +G ++ EG+ A +FE +P+ +T WY + I +R + Y Sbjct: 1215 PSFHGR-QGRLRVKEGREASVYFEISGKPKPSVT----WYKDDVVIGDEDRNVDIYSRGS 1269 Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141 I R ED G Y ARN G A + + VE + + Sbjct: 1270 SYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEV 1311 Score = 34.3 bits (75), Expect = 2.5 Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 6/127 (4%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 ++ ++ E P +++ DV EG C+V +PT ++W N + R Sbjct: 1304 DVEVKQEVMIAPEIRQQLQAE-DVTEGDDCRLTCKVSGYPEPT--LEWLKNNELLSDNDR 1360 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK--RDIVLESQLP- 3800 T D L I + DA Y N G +++AK+ K + VLE Sbjct: 1361 FKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDV 1420 Query: 3801 QGMSGEK 3807 +G+ G++ Sbjct: 1421 KGVEGDE 1427 Score = 34.3 bits (75), Expect = 2.5 Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 4134 VTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTGKIEVI 4183 V G PKP V W NG + +G ++ G YH I ++ + D G + + Sbjct: 1532 VRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCL 1582 Score = 34.3 bits (75), Expect = 2.5 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 2890 AEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949 +E A L + P+ E + E +P A+ E L + + K PD + WY Sbjct: 1788 SERAELTVKEKLIAPEFEGRETE--VPFRAK----EKSDLEVSYNINGKPSPD--VSWYR 1839 Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995 + ++L G + +L + +V D+G Y C+A N+ G A Sbjct: 1840 DDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVGSA 1885 Score = 34.3 bits (75), Expect = 2.5 Identities = 61/249 (24%), Positives = 93/249 (37%), Gaps = 39/249 (15%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 V W+ +G L SR + I V D G Y C+A NR G + SC +++K Sbjct: 2660 VTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEIK 2719 Query: 3651 GRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEG 3710 EP+ S + T + +L HK F E VP G Sbjct: 2720 -------EPK--SVDSTDTRAPGQLIPVKHK---------------FDFE-----GVP-G 2749 Query: 3711 GPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL--NDFGFIALDIDYIYARDAGEY 3768 G D V+ + I+WF G + L +D ++L ++ + DAG Y Sbjct: 2750 GKARCDVLVKK--SDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTY 2807 Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828 C G T ++ K+ L L + +S EK L +G+ + K + + Sbjct: 2808 RCVVHTPAGQTTIRGELHIKEKQQAPL--FLDEKVSQEKF-SLPQGQ--EMNKSFTVTGS 2862 Query: 3829 PPKFITQIK 3837 P IT K Sbjct: 2863 PTPHITWYK 2871 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 800 PTMRVEWYKDGRPITASSR--ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857 P VEW+KDG+ + S R + S N Y L I H+ ED GSY A + G + T Sbjct: 3158 PKAVVEWFKDGKFLYDSRRMGVRSCGNSHY--LVIYHVTPEDEGSYKCVASSTNGRSSRT 3215 Query: 858 ASIRV 862 + V Sbjct: 3216 FDLSV 3220 Score = 34.3 bits (75), Expect = 2.5 Identities = 18/79 (22%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 916 KDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVT 975 + ++++ EG + + ++ L V W KDG ++ + RI + L I S Sbjct: 3594 RQELNVPEGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAA 3651 Query: 976 VHDAGHYTCRAYNAIGQAT 994 D+G Y C + +G ++ Sbjct: 3652 PEDSGLYKCEGVSTLGTSS 3670 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 2/79 (2%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 EG V + A V + P +EWFK+G L+ L L + DSG Y Sbjct: 3894 EGCEVSMMANVRGKPAPT--VEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTY 3951 Query: 2716 TCKATNLLGEAVSTASIKI 2734 ATN LG A ++ + Sbjct: 3952 KFVATNDLGSAYRIFNLNV 3970 Score = 34.3 bits (75), Expect = 2.5 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 3/112 (2%) Query: 3540 GYSGTV-DTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGK 3598 G G V + + E E G PEF + + S + V W+ +G Sbjct: 4928 GIGGAVLNLIIHEREFG--PEFIDEEGEYVKVVRSEGVANITFTVRGNPRPEVIWYKDGT 4985 Query: 3599 PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 L +R+ T + L I + DAG Y C+A ++ G+ SC L V+ Sbjct: 4986 LLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCILDVQ 5037 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433 QRP + ++ + G+ A F+ + P K+ W+++E + R T + G Sbjct: 5343 QRPRLSDNMKELFATVGGE-ARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGI 5399 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459 ++ I V+ D G Y ASN G+ Sbjct: 5400 YTLIIKEVQLSDSGTYKFVASNKAGK 5425 Score = 34.3 bits (75), Expect = 2.5 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 7/92 (7%) Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026 ++K P F + ++ +V +E + E G P V+W+ GK LLH ++ + Sbjct: 5435 MEKTVAPEFPDR-ETLEQVVGVEGREVELSTVVKGLPRPSVKWYKEGK-LLHTSKALTVS 5492 Query: 4027 DFGYVAMNFGWVYP---EDSGEYLCRATNLYG 4055 G ++ W+ E SG Y C ATN G Sbjct: 5493 TSGDT--HYVWIPSAKHEHSGRYRCEATNSNG 5522 Score = 33.9 bits (74), Expect = 3.2 Identities = 30/129 (23%), Positives = 48/129 (37%), Gaps = 3/129 (2%) Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLT 1074 G K DA + S R + VK Q P+ + ++ EG+S + + + + Sbjct: 60 GAYKCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPK-- 117 Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134 V WY +GK + I L I DSG Y A+N G + + Sbjct: 118 PEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVN 177 Query: 1135 VETRSSIDT 1143 V+ + T Sbjct: 178 VKVKGKAPT 186 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 2/74 (2%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576 P ++ EG+ + V G P WY +G +K R + + D TL I V + Sbjct: 193 PDKVQEGEQYKFTCAVT--GKPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQD 250 Query: 2577 DAGLYMCKAINRAG 2590 D G Y + N G Sbjct: 251 DKGTYKVEITNDLG 264 Score = 33.9 bits (74), Expect = 3.2 Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 3/99 (3%) Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474 EK P F + IE ++ GE A L P KV WY + L + Sbjct: 626 EKVVQPEFDKEVKPIE-VKHGEEA--TTSLEIKGKPKPKVTWYKDLVPLLETRSIQLKSV 682 Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 LEI P+D G+Y C A N G A + +KV+ Sbjct: 683 GDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVK 721 Score = 33.9 bits (74), Expect = 3.2 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 2/66 (3%) Query: 89 AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTA 148 A F + G P P + W P+V ++ + E+ SL I + D G Y C A Sbjct: 843 ASFHCEFSGKPEPEIEWFCGPNPIVPGGRFHV--TEEGNIQSLAISDLKLEDAGNYKCVA 900 Query: 149 RNQYGE 154 N G+ Sbjct: 901 SNAAGK 906 Score = 33.9 bits (74), Expect = 3.2 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 9/135 (6%) Query: 2924 VEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGI 2983 ++GQ +++ V K P+ I W +G+ L ++ L L V D+G+ Sbjct: 934 LDGQDVNISTWVRGKPKPE--IVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGM 991 Query: 2984 YTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDD 3043 YTC+A N G T+ + + L ++ P LE I+ E + Q + Sbjct: 992 YTCRAKNNAGIVSKDVTI---TVEALQKKGDTPTFMSKLEPIEITEG----DDFQLSCNV 1044 Query: 3044 TGRPPEFTTVFKDIV 3058 TGRP F+D V Sbjct: 1045 TGRPQPEVQWFRDEV 1059 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/106 (25%), Positives = 45/106 (42%), Gaps = 7/106 (6%) Query: 1432 KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH 1491 K D+ ++P + + + V EG +F K++ ++EW+ +T G Sbjct: 1105 KADVTVLKKHLRPEVLQKMDDVRTV-EGGKANFAVKIDAFPKP--EIEWYLGATKITDGG 1161 Query: 1492 RFRPIHD---FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 RF+ D Y+ L I D+ +D+G C A N G V L Sbjct: 1162 RFKIKTDKENCSYI-LFIDDVKLDDAGTVKCSATNAAGKTVVRADL 1206 Score = 33.9 bits (74), Expect = 3.2 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 2/69 (2%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVT--LDLVDVYERDSGIYTCKAYNKRGEAFTS 2998 P +IEWY + G RFK+ +D + L + DV D+G C A N G+ Sbjct: 1144 PKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVR 1203 Query: 2999 STVYCTSKD 3007 + + K+ Sbjct: 1204 ADLEVEEKN 1212 Score = 33.9 bits (74), Expect = 3.2 Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 7/115 (6%) Query: 1566 RTDMVDEVTTQAPICTTSLKNVEIKEGQRA--HFERRLIPVSDATLKVEWYHNNKPLKSG 1623 R D+ E AP + +KEG+ A +FE P T WY ++ + Sbjct: 1203 RADLEVEEKNVAPSFHGRQGRLRVKEGREASVYFEISGKPKPSVT----WYKDDVVIGDE 1258 Query: 1624 SRFTETNNFGF-VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYL 1677 R + + G I PED GTY C A N +G A + V K+ + + Sbjct: 1259 DRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMI 1313 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 5/103 (4%) Query: 619 ERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678 +RA + + ++ QF+ PL+ + + ++ + R G P + W KNG+ Sbjct: 1494 QRAELEVKERDYAPIFEEKQFLEPLE-IQVRQPVEVSYHVR----GRPKPTVTWWKNGKE 1548 Query: 679 IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAE 721 + Y +L +L +D+G Y C A + G AE Sbjct: 1549 LRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAE 1591 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 3/98 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P+ K+++ + EG +E +V P +EW+ + G R + T + T Sbjct: 1999 PVIKEVSKTFE-VSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHT 2055 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHW 2739 LSI + + + Y C A N G A + I +R + Sbjct: 2056 LSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREY 2093 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 2/95 (2%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P F ++ + EG L + PT ++W + PV GHR + +D Sbjct: 2431 EAPSFKSQLQPVILEEGGTGVLVGEVAGKPLPT--IQWMKDDYPVLFGHRVRPQFDGRTC 2488 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 + A D G Y C N GEA + + V V+ Sbjct: 2489 KVIFREALIGDGGMYECIIKNQCGEASSKALVGVN 2523 Score = 33.9 bits (74), Expect = 3.2 Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 16/154 (10%) Query: 4000 VGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAM-NFGWVYPEDSGEYLCRATNLYGMDE 4058 +G+P V W+ +G LL+ T + G + N +V PED+G Y+C A N G Sbjct: 2653 MGNPRPFVTWYKDGI-LLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSF 2711 Query: 4059 TKAVIKTTGKPGI-VYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLP 4117 I+ + D++ P + ++ + E V KARC V V Sbjct: 2712 RSCTIEIKEPKSVDSTDTRAPGQLIPVKHKFDFEG---------VPGGKARC-DVLVKKS 2761 Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 D + + EW R + K +++ +G T+ Sbjct: 2762 DIIDI---EWFRGTNMLRDGDKYKILKSDDGQTL 2792 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 3/83 (3%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P+F L + ++ EG F + G P ++W++++ I + RI D V Sbjct: 3982 PIFVTELSPL-SVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVK 4038 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 + I + ED+G Y N G Sbjct: 4039 LLIGQITLEDQGQYKVVLKNESG 4061 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 +P + + +ID + EG + +I G P KVEWFR+ + ++ R T + Sbjct: 4848 KPEVAEKMTDIDAV-EGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTS 4904 Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458 ++ I + D G Y +N G Sbjct: 4905 TLVIRNCTTNDTGPYKVIGTNECG 4928 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/120 (21%), Positives = 51/120 (42%), Gaps = 3/120 (2%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 ++P+ +K T G E T+ P ++ WY + ++ R+ + G Sbjct: 5343 QRPRLSDNMKELFATVGGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIY 5400 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 L I D+GTY A+N G+ ++V K+ + + D + L+++ +E E Sbjct: 5401 TLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKT-VAPEFPDRETLEQVVGVEGRE 5459 Score = 33.9 bits (74), Expect = 3.2 Identities = 15/56 (26%), Positives = 29/56 (51%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 G+P V W+++ L+ D++ + +TI + +D G Y+C A + LG+ Sbjct: 5764 GNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCEAQSRLGK 5819 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 P I WY +G+ ++ R K + D TL + DV + D G Y + N G +++ Sbjct: 212 PKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTAD 271 Query: 3001 VYCT---SKDNLIERTQHPKGTEG 3021 + T +K ++ + ++ + EG Sbjct: 272 LEVTPKPAKPEVVRKMENVESVEG 295 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/104 (21%), Positives = 42/104 (40%), Gaps = 3/104 (2%) Query: 61 ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120 + P +P I ++ + + G + K + G P P V W + PL ++ Sbjct: 720 VKVAEPQGETPTITTEM-TDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPLKANHRLVP 778 Query: 121 RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164 + E+ ++L + I D G Y C N +G + ++ E Sbjct: 779 SFEERM--IALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVE 820 Score = 33.5 bits (73), Expect = 4.3 Identities = 17/75 (22%), Positives = 32/75 (42%) Query: 4092 ASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 A+ + T ++ ++ P F D + +G+ V G PKP ++WL +G + Sbjct: 903 AAGKTTTRAELKVNEKHFAPEFEDWKDTIDALDGQDVNISTWVRGKPKPEIVWLKDGEEL 962 Query: 4152 VNGSRYKLTYDGMYH 4166 N ++ G H Sbjct: 963 RNTMHVQIKCYGDLH 977 Score = 33.5 bits (73), Expect = 4.3 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 3/98 (3%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637 P + L+ +EI EG F+ +V+W+ + +K RF + + AL Sbjct: 1021 PTFMSKLEPIEITEGD--DFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 1078 Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675 + +D G Y C N G +V+S + KK + Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFG-SVSSKADVTVLKKHL 1115 Score = 33.5 bits (73), Expect = 4.3 Identities = 15/54 (27%), Positives = 28/54 (51%) Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS 3817 D G Y C A N G+A T I K+++++ ++ Q + E + E + R++ Sbjct: 1282 DKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLT 1335 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/86 (25%), Positives = 34/86 (39%) Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997 K PD EW + K ++ + D TL+ V D G YT N G ++ Sbjct: 1632 KGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYS 1691 Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLE 3023 S+ + + E + K EG+E Sbjct: 1692 SANLDIVKSKSKPEILETMKDAEGIE 1717 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 1/78 (1%) Query: 1204 MGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHT 1263 MG+P V W+ +G + SR +I DTG Y A N LGS+ Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFR 2712 Query: 1264 SAIVRVIERSDI-VTDTQ 1280 S + + E + TDT+ Sbjct: 2713 SCTIEIKEPKSVDSTDTR 2730 Score = 33.5 bits (73), Expect = 4.3 Identities = 18/70 (25%), Positives = 33/70 (47%) Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508 +P V WY +G L SR I PED+G Y+C A+N G + + Sbjct: 2655 NPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSC 2714 Query: 3509 SMKVQGKRNI 3518 +++++ +++ Sbjct: 2715 TIEIKEPKSV 2724 Score = 33.5 bits (73), Expect = 4.3 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 2/82 (2%) Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843 E A EA + V PT VEW+ + R +L I +L ED G Y Sbjct: 3298 ECSEARLEAHVAGVPRPT--VEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPY 3355 Query: 844 TVRAVNKLGEAISTASIRVAAR 865 + A N+ G S + V R Sbjct: 3356 KIIATNEHGSTGSVVDLTVKER 3377 Score = 33.5 bits (73), Expect = 4.3 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 5/109 (4%) Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301 PR + + R V +G A F +VE P ++ ++H + S R+ I+ S Sbjct: 3783 PRIIEKPRDVDAV-DGTDAKFTVRVEGFPQP--KVTWFHESTKIVSRGRYEISRVGDLYS 3839 Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQRPE 2348 L I+ G Y A N G T+ + VT + I++ S+ PE Sbjct: 3840 LVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQDFAPIVAGSEMPE 3888 Score = 33.5 bits (73), Expect = 4.3 Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 6/119 (5%) Query: 1416 SGLEKIQYLEDTSRYKKT-DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474 +G+ K + D T D+ +KP FV R + + V G+ F +++ Sbjct: 4522 TGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGE-ASFSVRVKGFPRP 4580 Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR 1533 K+ W+K+ + RF + L I ++ +DSG Y C N VG + +CR Sbjct: 4581 --KIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGKE--TCR 4635 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 7/114 (6%) Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494 G A FE + T P K+ WY + +L++ R+ + G L I DSG Y Sbjct: 5359 GGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYK 5416 Query: 3495 CRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTL 3548 A N G+ ++V K + + P T++++ +EG + T+ Sbjct: 5417 FVASNKAGKTTFLGYLEVMEK---TVAPEFPD--RETLEQVVGVEGREVELSTV 5465 Score = 33.5 bits (73), Expect = 4.3 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP-IHDFGY 1501 KP + K IE EG F+ + +V+W++ +T +R+ + G Sbjct: 5639 KPEINEKLKKIE-AFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGM 5695 Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVG 1526 +L I + ED G+Y C AVN G Sbjct: 5696 ASLTIRKIRQEDGGLYGCVAVNEYG 5720 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGV 2448 E A FD + PT VEW++ + I S + D G S+ I + +D G Sbjct: 4 ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61 Query: 2449 YMCRASNLLGE 2459 Y C A+N G+ Sbjct: 62 YKCVATNDAGQ 72 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 2/97 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+ L++ EG ++ +PT+ EWLKN + + + RF + F +L Sbjct: 1315 PEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGTL 1372 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733 + ++ + D+ Y + G + A L V + T Sbjct: 1373 TIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCT 1409 Score = 33.1 bits (72), Expect = 5.7 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 3/85 (3%) Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501 +KP K+ E V EG E K+ V VEW+ V G RF+ + Y Sbjct: 1997 VKPVIKEVSKTFE-VSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDY 2053 Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVG 1526 L I D+ + + Y C A N G Sbjct: 2054 HTLSIRDVGDQAAASYKCVAFNNAG 2078 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/91 (26%), Positives = 34/91 (37%), Gaps = 2/91 (2%) Query: 4117 PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF-DIPKTRQY 4175 P V V EGE A+ V G PK V W +G + + R + G H+ I Sbjct: 3137 PKPVIVNEGEEAQMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPE 3196 Query: 4176 DTGKIEVIXXXXXXXXXXXXXLKV-IPRHDD 4205 D G + + L V +P+ D Sbjct: 3197 DEGSYKCVASSTNGRSSRTFDLSVKVPKPKD 3227 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 4/91 (4%) Query: 917 DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFFNFGYVALTIKSV 974 + + EG F+ R+ G VEW + + S + I G +L + V Sbjct: 3495 NDVQAVEGWKVQFQTRIT--GYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDV 3552 Query: 975 TVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005 T D G Y C A N+ G + NL + K+ Sbjct: 3553 TKDDIGTYKCLATNSAGSSACRINLDVKDKQ 3583 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 1318 HNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY--EFDYVALDLLSV 1375 ++++ VEG V + R+ G VEW+ + +++ A E +L + V Sbjct: 3495 NDVQAVEGWKVQFQTRI--TGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDV 3552 Query: 1376 YPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406 +D G Y C ATN G + L V K+ Sbjct: 3553 TKDDIGTYKCLATNSAGSSACRINLDVKDKQ 3583 Score = 33.1 bits (72), Expect = 5.7 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 14/143 (9%) Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY---DGMYHFDIPKTRQYD 4176 V EG +F R+TG+P P V W + + +YK+ DG+Y + + D Sbjct: 3497 VQAVEGWKVQFQTRITGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDD 3556 Query: 4177 TGKIEVIXXXXXXXXXXXXXLKV--------IPRHDDYRGVLKNAPRPWYDETTQYQRTE 4228 G + + L V IP H+D + + N P +++ Sbjct: 3557 IGTYKCLATNSAGSSACRINLDVKDKQYAPEIPGHEDRQEL--NVPEGQEINMDVVIKSK 3614 Query: 4229 TELEKT-FEERQVLQRQGVIDHR 4250 LE + +++ ++LQ ID R Sbjct: 3615 PRLEVSWYKDGELLQDTKRIDIR 3637 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC--DFGFVILEISPTYPEDSG 3491 EG F+ R+T P+ VEWY L +++ + G L ++ +D G Sbjct: 3501 EGWKVQFQTRITGYPYPH--VEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIG 3558 Query: 3492 EYLCRAYNNYGEAVTTASMKVQGKR 3516 Y C A N+ G + ++ V+ K+ Sbjct: 3559 TYKCLATNSAGSSACRINLDVKDKQ 3583 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/93 (21%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637 P + L ++++ EG A ++ + T VEW+ +++ + + R + L Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTL 3744 Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 + +D G Y C A N G +S + +V+ Sbjct: 3745 IFETVNIQDRGAYRCTATNQEGSTSSSAVIVVN 3777 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 P+ +EW+ + +++ R + + TL V +D G Y C A N+ G +SS Sbjct: 3714 PEPTVEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGST-SSSA 3772 Query: 3001 VYCTSKDNLIER-TQHPKGTEGLE 3023 V ++ ++ R + P+ + ++ Sbjct: 3773 VIVVNRASITPRIIEKPRDVDAVD 3796 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 2/80 (2%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 +G + F VE P K+ WF + + S RY+ + SL I G Y Sbjct: 3796 DGTDAKFTVRVEGFPQP--KVTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTY 3853 Query: 2847 TCKATNSKGSATTSGSLRCT 2866 C ATN G T L T Sbjct: 3854 KCIATNDAGKVTAHCHLDVT 3873 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 1/69 (1%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169 P FV TV EGE +TG P P+V W N + + + +DG + + Sbjct: 4753 PSFVIELTPTTVTEGESTALEVEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIV 4812 Query: 4170 PKTRQYDTG 4178 +T D G Sbjct: 4813 RRTTLEDAG 4821 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 3/71 (4%) Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GYVSLNIMHLRAEDAGS 842 E A F+ + PT VEWY+ I +S + + + G SL I L +DAG+ Sbjct: 4 ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61 Query: 843 YTVRAVNKLGE 853 Y A N G+ Sbjct: 62 YKCVATNDAGQ 72 Score = 32.7 bits (71), Expect = 7.5 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Query: 2941 PDLKIEWYFN-GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 P +EWY K+ G L D G +L + D+ + D+G Y C A N G+ Sbjct: 18 PKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQ 72 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 1/64 (1%) Query: 1611 VEWYHN-NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669 VEWY NK SG ++ G +L I +D+G Y C A N G+ G V Sbjct: 22 VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRGDLSV 81 Query: 1670 HSKK 1673 K+ Sbjct: 82 KEKQ 85 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 2/79 (2%) Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161 +E + P F + V+EG A ++G PKP V W + I + R Y Sbjct: 1206 LEVEEKNVAPSFHGRQGRLRVKEGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIY 1265 Query: 4162 D--GMYHFDIPKTRQYDTG 4178 Y+F I + R D G Sbjct: 1266 SRGSSYYFTIKQARPEDKG 1284 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/70 (28%), Positives = 33/70 (47%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P+ +EWL+N + ++R T D L ++ V D+ Y N+ GE +S Sbjct: 1340 GYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSS 1399 Query: 1798 STLFVQSKAS 1807 + L V K + Sbjct: 1400 AKLKVIRKCT 1409 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 6/106 (5%) Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471 + + K K P + + E + G+ A F+ ++ P +VEWY + G R+ Sbjct: 1697 IVKSKSK-PEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCL 1752 Query: 3472 FCDF--GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 D G + I+ ED G Y A+N+ G+ A + V+ K Sbjct: 1753 TQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 3/91 (3%) Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339 E P F +Q+Q V L EG + + P ++W + + GHR R D Sbjct: 2431 EAPSFKSQLQPVI-LEEGGTGVLVGEVAGKPLPT--IQWMKDDYPVLFGHRVRPQFDGRT 2487 Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKA 3370 + + G YEC+ N+ G S+KA Sbjct: 2488 CKVIFREALIGDGGMYECIIKNQCGEASSKA 2518 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 2/80 (2%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 EG+ + V R P +EWFK+G L R+ L I + +D G Y Sbjct: 3144 EGEEAQMMVSVRGR--PKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSY 3201 Query: 2716 TCKATNLLGEAVSTASIKIE 2735 C A++ G + T + ++ Sbjct: 3202 KCVASSTNGRSSRTFDLSVK 3221 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 2/85 (2%) Query: 917 DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTV 976 + I ++EG A + G VEW KDG+ + ++ + Y L + T Sbjct: 3888 EPIVVREGCEVSMMANVR--GKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQ 3945 Query: 977 HDAGHYTCRAYNAIGQATTSANLTI 1001 D+G Y A N +G A NL + Sbjct: 3946 ADSGTYKFVATNDLGSAYRIFNLNV 3970 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 2/93 (2%) Query: 3978 QIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTP--IYDFGYVAMNF 4035 Q ++ +E K + G P VEWF + + R+ + D G ++ Sbjct: 4259 QTSKMANVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLII 4318 Query: 4036 GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068 V EDSG Y A+N G T A + GK Sbjct: 4319 SDVQLEDSGSYRAVASNNLGEATTLAELTVKGK 4351 Score = 32.7 bits (71), Expect = 7.5 Identities = 17/69 (24%), Positives = 35/69 (50%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G+P+ V W ++G+ + + + L + + +D+GTY C A + LG++ + Sbjct: 5764 GNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCEAQSRLGKSFRT 5823 Query: 1798 STLFVQSKA 1806 L V+ +A Sbjct: 5824 YALKVEEQA 5832 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 3/81 (3%) Query: 649 MEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSG 707 +E G+ F+ IE PT +EW + I +S + + G SL + L D+G Sbjct: 3 VESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAG 60 Query: 708 EYTCRAVSATGVAETKAVLHV 728 Y C A + G + L V Sbjct: 61 AYKCVATNDAGQTSLRGDLSV 81 Score = 32.3 bits (70), Expect = 9.9 Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 8/94 (8%) Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV--TIGHRF 1493 ++E V ++P F K IE V G+ LE KV W+K+ P+ T + Sbjct: 624 VNEKV-VQPEFDKEVKPIE-VKHGEEA--TTSLEIKGKPKPKVTWYKDLVPLLETRSIQL 679 Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527 + + D L+II+ +D G Y C A N GT Sbjct: 680 KSVGDEH--TLEIINATPDDEGKYKCEATNKAGT 711 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 2/66 (3%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858 P + W KDG + + + I +G + L + + EDAG YT RA N G Sbjct: 949 PKPEIVWLKDGEELRNTMHV-QIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDV 1007 Query: 859 SIRVAA 864 +I V A Sbjct: 1008 TITVEA 1013 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%) Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984 EGQ + + PD +EWY +L + L + G L++ D+G Y Sbjct: 2109 EGQNAITNMTIRARPSPD--VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTY 2166 Query: 2985 TCKAYNKRG 2993 CKA N G Sbjct: 2167 ICKATNSIG 2175 Score = 32.3 bits (70), Expect = 9.9 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 5/100 (5%) Query: 3966 DVDKKQ--PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFT 4023 DV K+Q P F +Q+Q L E T ++A G P ++W + P+L +R Sbjct: 2424 DVPKEQWEAPSFKSQLQP-VILEEGGTGVLVGEVA--GKPLPTIQWMKDDYPVLFGHRVR 2480 Query: 4024 PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063 P +D + F D G Y C N G +KA++ Sbjct: 2481 PQFDGRTCKVIFREALIGDGGMYECIIKNQCGEASSKALV 2520 Score = 32.3 bits (70), Expect = 9.9 Identities = 16/53 (30%), Positives = 24/53 (45%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163 P F S V +EEG V G P P + W+ + ++ G R + +DG Sbjct: 2433 PSFKSQLQPVILEEGGTGVLVGEVAGKPLPTIQWMKDDYPVLFGHRVRPQFDG 2485 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/66 (27%), Positives = 31/66 (46%) Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932 +P V W+ +G L R + L+I + +D+G Y C+A + LG S Sbjct: 4179 NPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSC 4238 Query: 1933 RLNVQS 1938 L+V++ Sbjct: 4239 TLDVKA 4244 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/92 (22%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029 + P FV +++ T++ E + F ++ G P K+ W+ + L+++ RF + Sbjct: 4548 RMKPTFVERLREVTTVFGGEAS-FSVRVK--GFPRPKIVWYKDITRLINRGRFHISEEGD 4604 Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061 + V +DSG Y+C +N G + ++ Sbjct: 4605 LYNLTIENVGRDDSGTYMCILSNAVGKETCRS 4636 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 2/60 (3%) Query: 2177 EDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN-GLEKIRQLEAQGHSTRIEVE 2235 +D G Y C ATN+ GEA L V GH D P+ +E +G ST +EVE Sbjct: 4717 KDGGLYKCVATNEHGEASMLFNLDVEGHVP-EEDWSAPSFVIELTPTTVTEGESTALEVE 4775 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379 I G ++L ++ G V W+ +G I T + D L +L E Sbjct: 5159 ITITRGNQLNLNVTIR--GKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEH 5216 Query: 1380 SGVYTCQATNQLG 1392 +G Y+C+AT++LG Sbjct: 5217 AGTYSCEATSKLG 5229 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 V W+ +G +LT V+ I G V L I AG Y+C+AT++ G + +Q+ Sbjct: 5181 VVWYKDGNKILTSRNVQ-IRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAKFDVQI 5239 Query: 3650 KGRQGIILEPQLPSHFK 3666 + + P+ P+ K Sbjct: 5240 QAPEA---APKAPAFLK 5253 >SB_8819| Best HMM Match : I-set (HMM E-Value=0) Length = 1789 Score = 161 bits (390), Expect = 2e-38 Identities = 113/413 (27%), Positives = 188/413 (45%), Gaps = 21/413 (5%) Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463 P +PP FT +++P + E+EQ E D P I++ ++ P K + ++F Sbjct: 641 PKDKQQPPTFTSEVKPVQANENEQVSVVFEADLTPDSKIEFLKDGKPFKGDENSD-YSFD 699 Query: 4464 TKSILI-IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522 ++IL+ + +DS + V N+ G + + +E K+ + + + T + Sbjct: 700 GRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEIT---KP 756 Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 V V + V+L + T + WLK+GK PD R+ + TL++ + +D+G Sbjct: 757 VVVKEKEQVKLVFEADVTPDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTG 816 Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642 YECV N G +C + V K +PK + PE + P+K+ E F Sbjct: 817 TYECVIANKYG--KCSSPVDV-----KVEPK------HLKPEAVTPMKNIDAVESGQARF 863 Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNS 4700 ++ G P P +WY G + S ++ + D+ YTL I D G YK + N Sbjct: 864 EVEVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNL 923 Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760 AG T A+LKV + + A T + I V +GQ +I SK KP + WL++G Sbjct: 924 AGTTTNKAELKVKEKEVAPEF-IQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKT 982 Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + + G+ L+I + EDTGT+TC AT G+ + + VK + Sbjct: 983 LSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGE 1035 Score = 161 bits (390), Expect = 2e-38 Identities = 117/394 (29%), Positives = 177/394 (44%), Gaps = 28/394 (7%) Query: 4411 PIFTK-KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSIL 4468 P F K +++P V + E+A + G+P P + W+++ P++ S + Q + T SI Sbjct: 1231 PEFDKDEVEPIEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIR 1290 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528 I+R ED+ + A N G K S N + K P+F Q + VT Sbjct: 1291 IVR-TSPEDAGTYMCEATNPSG--KASKNFDIGIKGE-------APTFASKLQPIQVTEE 1340 Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588 +L KV+G + W K+G+ V+ D+R K + T TL D G+YE Sbjct: 1341 DECKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEV 1400 Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648 N+ G R A+ V + K PEI+ + D E + +F I G Sbjct: 1401 TNNFGTVRTSADVDVQKRSVK-------------PEIMGKVDDIEAVETEQAQFDIPIKG 1447 Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTA--DEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 P P V+WY G I F++S + D Y+L IS +D G YKCVA N AG+ T Sbjct: 1448 YPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKATA 1507 Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766 L V + + I V +G+ A +I K KP + W ++G ++ ET + Sbjct: 1508 RVNLDVKEKMFQPEFDR-DEVEPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRN 1566 Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 Q++ GN + I T +D GT+ C AT AG Sbjct: 1567 IQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAG 1600 Score = 150 bits (364), Expect = 2e-35 Identities = 172/732 (23%), Positives = 297/732 (40%), Gaps = 58/732 (7%) Query: 4095 QVTPEQVVEESKARCPPVFV-SLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN 4153 ++T E E+ +A PVF+ + V V+E E + P ++ WL +G Sbjct: 734 KITIEPKKEKKQA---PVFIHEITKPVVVKEKEQVKLVFEADVTPDSKIEWLKDGKPFTP 790 Query: 4154 GSRYKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKN 4212 R T+DG + + T DTG E + +KV P+H V Sbjct: 791 DQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPKHLKPEAV--- 847 Query: 4213 APRPWYDETTQYQ-RTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKR 4271 P D Q R E E+ + E + G K K+IK E + ++ Sbjct: 848 TPMKNIDAVESGQARFEVEVSGS-PEPKFEWYHGSTKLNDSDKHKIIK-AEDKPLYTLII 905 Query: 4272 KKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLD--QT 4329 + + L +L I + +T++ + KV VA Q +D Q Sbjct: 906 ENVDTTDGGLYKL-----ITSNLAGTTTNKAEL---KVKEKEVAPEFIQTDTKPIDVEQG 957 Query: 4330 EEVTEQRVQKKVTQKPRIP--DPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTET 4387 ++VT + K KP++ ++ K + + T + V+ K+ T + T T T Sbjct: 958 QDVTAS-FKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVI--KKSTPEDTGTYT 1014 Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447 + VK P + + K+QP +V E + + + G P P IKW+++ Sbjct: 1015 CTATNNIGKCSSDFTVNVKGEAPTL-SSKLQPVQVTEEDDCKLTCKVSGLPEPTIKWFKD 1073 Query: 4448 NFPIKNSPDFQIH-TFSTKS-ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRR 4505 P+K+ D +I T+ K+ L + + ++D + N GT + SA++ V+ + Sbjct: 1074 GEPVKS--DLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRN- 1130 Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKI-- 4562 V P ++ + R D + G KP+ V W ++ R K+ Sbjct: 1131 ------VKPEIVGKVHDIEALETEQARFDIPIKGYPKPV-VEWFHGPTRILDGGRFKLSE 1183 Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622 EE+ Y+L+I + D G Y+CVA N AG+ A V K + Sbjct: 1184 SEENDMYSLVISDLVMDDLGTYKCVANNDAGKTTARANLDV---------KEKMFQPEFD 1234 Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682 + +EP++ V +G+ S I GKP P V W+K K ++ SK Q D Y++RI Sbjct: 1235 KDEVEPIE---VKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRI 1291 Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742 PED G Y C A N +G+ + + + + + + L+ I V E + Sbjct: 1292 VRTSPEDAGTYMCEATNPSGKASKNFDIGI----KGEAPTFASKLQPIQVTEEDECKLTC 1347 Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802 +++ +PTI+W ++G + + ++G L +D G + T G V Sbjct: 1348 KVSGLPEPTIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTV 1407 Query: 4803 ETSAKLVVKSKT 4814 TSA + V+ ++ Sbjct: 1408 RTSADVDVQKRS 1419 Score = 144 bits (348), Expect = 2e-33 Identities = 106/409 (25%), Positives = 187/409 (45%), Gaps = 32/409 (7%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-TFSTKSI-L 4468 P F K+QP +V E ++ + + G P P IKW+++ P+K+ D +I T+ K+ L Sbjct: 1326 PTFASKLQPIQVTEEDECKLTCKVSGLPEPTIKWFKDGEPVKS--DLRIKPTYDGKTCTL 1383 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528 + + ++D + N GT + SA++ V+++ V P ++ Sbjct: 1384 TFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRS-------VKPEIMGKVDDIEAVET 1436 Query: 4529 QLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYPQDSGKYE 4585 + + D + G KP+ V W ++ R KI E E+ Y+L+I D G Y+ Sbjct: 1437 EQAQFDIPIKGYPKPV-VEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYK 1495 Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645 CVA N AG+A V+L + +P+ + +EP++ V +G+ S + Sbjct: 1496 CVASNDAGKATAR----VNLDVKEKMFQPEFDR-----DEVEPIE---VKQGEEASTSLE 1543 Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705 I GKP P V WYK K+++ ++ Q+ + Y++ I P+D G Y C A N AG T Sbjct: 1544 IQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAG--T 1601 Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQIT-SKIKPTIQWLREGALIPET 4764 + K + + L + L+ + V EG + +T KP I+W ++G + Sbjct: 1602 SSRKFDIKVSGEGPKL--ASELQPMQVTEGDDCKLSCNVTEGTTKPIIKWFKDGEPVKSD 1659 Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + + G +L + D G + T G V++SA + V+ + Sbjct: 1660 HRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRR 1708 Score = 136 bits (328), Expect = 5e-31 Identities = 118/448 (26%), Positives = 199/448 (44%), Gaps = 36/448 (8%) Query: 4376 KEITRKITSTETTEIEHKAQTQERVVEGPVKPSKP----PIFTKKM-QPCRVFEHEQARF 4430 K T+K + T + +K V+ ++P K P+F ++ +P V E EQ + Sbjct: 708 KNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITKPVVVKEKEQVKL 767 Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSI-LIIRQVFVEDSAVFAAVAENR 4488 E D P I+W ++ P +PD + +TF + I L+++ V+D+ + V N+ Sbjct: 768 VFEADVTPDSKIEWLKDGKPF--TPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANK 825 Query: 4489 GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548 G KCS+ + V+ + + + V P + A V SGQ R + +V+G+ W Sbjct: 826 YG--KCSSPVDVKVEPKHLKPEAVTPMKNIDA----VESGQ-ARFEVEVSGSPEPKFEWY 878 Query: 4549 KNGKKVQPDIRNKIL--EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606 K+ ++KI+ E+ YTL+I D G Y+ + N AG Sbjct: 879 HGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAG------------- 925 Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665 T +K + + K PE I+ I V +GQ + S KI KP P V W K K + Sbjct: 926 TTTNKAELKVKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSS 985 Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725 SK + D Y L I ++ PED G Y C A N+ G+ ++ V +A L + Sbjct: 986 SKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGK--CSSDFTVNVKGEAPTLS--S 1041 Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785 L+ + V E + +++ +PTI+W ++G + + ++G L Sbjct: 1042 KLQPVQVTEEDDCKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITM 1101 Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSK 4813 +D G + + T G V TSA + V+ + Sbjct: 1102 DDGGEYEVQVTNNFGTVRTSADIAVQRR 1129 Score = 120 bits (288), Expect = 4e-26 Identities = 97/396 (24%), Positives = 161/396 (40%), Gaps = 30/396 (7%) Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465 K S P K+ E EQA+F++ G P P+++WY I + F+I Sbjct: 1417 KRSVKPEIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEWYHGPTRILDGGRFKISESEEN 1476 Query: 4466 SI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL-TAQN 4522 + L+I + ++D + VA N G A NL V+EK Q P F + Sbjct: 1477 DMYSLVISNLIMDDLGTYKCVASNDAGKATARVNLDVKEKMFQ-------PEFDRDEVEP 1529 Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 + V G+ ++ G V W K+GK ++ +++ TY++ I+ P D G Sbjct: 1530 IEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVG 1589 Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642 Y C A N AG + K K + P++ L+ V EG + Sbjct: 1590 TYMCEATNKAGTS---------------SRKFDIKVSGEGPKLASELQPMQVTEGDDCKL 1634 Query: 4643 SCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701 SC + G P ++W+K + +K + S L + D GDY+ N Sbjct: 1635 SCNVTEGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKF 1694 Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761 G V +A + V + + + + + DI E + A+F I KP ++W I Sbjct: 1695 GTVKSSADIDVQRRNVKPEI--VGNVDDIEAVETEQARFDITIKGYPKPVVEWYHGPTRI 1752 Query: 4762 PETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRA 4795 + F++ N + L+I + +D GT+ C A Sbjct: 1753 LDGGRFKISESEENDMYSLVISDLAMDDLGTYKCVA 1788 Score = 105 bits (251), Expect = 1e-21 Identities = 82/331 (24%), Positives = 144/331 (43%), Gaps = 39/331 (11%) Query: 248 SDVQISTEI--DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 SDV+I+ E ++ PV +I KP K +E F+ ++ P ++ W K+G+ Sbjct: 731 SDVKITIEPKKEKKQAPVFIHEIT-KPVVVKEKEQVKLVFEADVT--PDSKIEWLKDGKP 787 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365 + + TL +++T D+G Y C++ + Y SP + Sbjct: 788 FTPDQRSDYTFDGRIITLMLKDTSVKDTGTYE--------CVIANKYGKCSSPVD----- 834 Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425 +++ K L P+ V ++ D E RF+ V+G P P+ W Sbjct: 835 -----------------VKVEPKHLKPEAVTPMKNIDAVESGQARFEVEVSGSPEPKFEW 877 Query: 426 FINDRQIRDDYNHKIL-VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484 + ++ D HKI+ + + L+I NV +D G+ + N +G T + L V E Sbjct: 878 YHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAELKVKE 937 Query: 485 KEQVVAPKFVER-FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543 KE VAP+F++ ++V +G+ V + + P P++TW KDG + + + G Sbjct: 938 KE--VAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRG 995 Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574 L I ++ D Y CTA N G ++ Sbjct: 996 DTYELVIKKSTPEDTGTYTCTATNNIGKCSS 1026 Score = 104 bits (250), Expect = 2e-21 Identities = 107/467 (22%), Positives = 190/467 (40%), Gaps = 52/467 (11%) Query: 122 YNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI--QPEGXXXXXXXXXXXXXY 179 Y+ ++ L K D G Y C N++G++ V I +P+ Sbjct: 696 YSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITK 755 Query: 180 RHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL----LREVS 235 V + E + T S K+ + + D TF+ R+ L++ S Sbjct: 756 PVVVKEKEQVKLVFEADVTPDS----KIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTS 811 Query: 236 FRESITKRYVGESDV-QISTEIDRSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNP 293 +++ T V + + S+ +D + P P+ +N E A+F+V++SG+P Sbjct: 812 VKDTGTYECVIANKYGKCSSPVDVKVEPKHLKPEAVTPMKNIDAVESGQARFEVEVSGSP 871 Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHT--TLRVRNTQKSDSGHYTLLAENPNGCIVTSG 351 P+ W+ +L +S+KH+II + TL + N +D G Y ++TS Sbjct: 872 EPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYK---------LITSN 922 Query: 352 YLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV-CQDRDVTEGKMTR 410 T T + E +++ EK +AP+F++ + DV +G+ Sbjct: 923 LAG-----------------TTTNKAE----LKVKEKEVAPEFIQTDTKPIDVEQGQDVT 961 Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARN 469 ++ +P P+VTW + + + + +I+ G+ + L+I T D+G TC A N Sbjct: 962 ASFKIKSKPKPQVTWLKDGKTLSS--SKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATN 1019 Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529 G+ + +NV + AP + + V E + L + G P P I W KDG Sbjct: 1020 NIGKCSSDFTVNVKGE----APTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIKWFKDGE 1075 Query: 530 PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 P+ + ++ DG TL D Y+ N G+ T A Sbjct: 1076 PVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSA 1122 Score = 103 bits (247), Expect = 4e-21 Identities = 57/197 (28%), Positives = 97/197 (49%), Gaps = 4/197 (2%) Query: 379 TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438 T I + + + P+ V D + E + RFD + G P P V WF +I D Sbjct: 1120 TSADIAVQRRNVKPEIVGKVHDIEALETEQARFDIPIKGYPKPVVEWFHGPTRILDGGRF 1179 Query: 439 KILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VER 496 K+ +E + ++L+I+++ + D G CVA N +G+T + L+V KE++ P+F + Sbjct: 1180 KLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGKTTARANLDV--KEKMFQPEFDKDE 1237 Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556 + V++GE + G P P +TW KDG P+ + ++ + G ++ I R Sbjct: 1238 VEPIEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPE 1297 Query: 557 DAAWYQCTAQNVAGSTA 573 DA Y C A N +G + Sbjct: 1298 DAGTYMCEATNPSGKAS 1314 Score = 103 bits (246), Expect = 5e-21 Identities = 112/512 (21%), Positives = 193/512 (37%), Gaps = 42/512 (8%) Query: 68 EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127 E +P + K QG + K++ P P V+W + L + T Sbjct: 939 EVAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTY 998 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET-V 186 + L+IK+ P D G YTCTA N G+ + +G + + Sbjct: 999 E--LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEAPTLSSKLQPVQVTEEDDCKL 1056 Query: 187 EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG 246 K G T + + + V + T D K T ++ + E + Sbjct: 1057 TCKVSGLPEPTIKWFKDGEPVK--SDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNN 1114 Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306 V+ S +I V P +I K + + E A+F + + G P+P V WF R+ Sbjct: 1115 FGTVRTSADIAVQRRNVKP-EIVGKVHDIEALETEQARFDIPIKGYPKPVVEWFHGPTRI 1173 Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ 366 ++ R + ++ ++ Y+L V S + + T V + Sbjct: 1174 LDGG-------------RFKLSESEENDMYSL---------VISDLVMDDLGTYKCVANN 1211 Query: 367 RSQYITDTQQRETEERIEISEKALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425 D + +++ EK P+F K + +V +G+ + G+P PEVTW Sbjct: 1212 ------DAGKTTARANLDVKEKMFQPEFDKDEVEPIEVKQGEEASTSLVIRGKPKPEVTW 1265 Query: 426 FINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484 F + + +R+ N I G+ +++ I + D+G C A N SG+ + + + Sbjct: 1266 FKDGKPLRESKN--IQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKG 1323 Query: 485 KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544 + AP F + + V E + L + G P P I W KDG P+ + ++ DG Sbjct: 1324 E----APTFASKLQPIQVTEEDECKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPTYDGK 1379 Query: 545 ASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 TL D Y+ N G+ T A Sbjct: 1380 TCTLTFKGITMDDGGEYEVEVTNNFGTVRTSA 1411 Score = 102 bits (245), Expect = 6e-21 Identities = 53/199 (26%), Positives = 101/199 (50%), Gaps = 4/199 (2%) Query: 379 TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438 T +++ ++++ P+ + D + E + +FD + G P P V W+ +I D Sbjct: 1409 TSADVDVQKRSVKPEIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEWYHGPTRILDGGRF 1468 Query: 439 KILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ER 496 KI +E + ++L+I+N+ + D G CVA N +G+ R+N+ KE++ P+F + Sbjct: 1469 KISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKAT--ARVNLDVKEKMFQPEFDRDE 1526 Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556 + V++GE + G P P++TW KDG + +++ + G ++ I R Sbjct: 1527 VEPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPD 1586 Query: 557 DAAWYQCTAQNVAGSTATR 575 D Y C A N AG+++ + Sbjct: 1587 DVGTYMCEATNKAGTSSRK 1605 Score = 99.5 bits (237), Expect = 6e-20 Identities = 112/496 (22%), Positives = 192/496 (38%), Gaps = 43/496 (8%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGE 143 QG A +RG P P V+W + PL E + GD S+ I + P D G Sbjct: 1245 QGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQK---SIGDTYSIRIVRTSPEDAGT 1301 Query: 144 YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET-VEHKAYGTQGYTTEQSR 202 Y C A N G+A + I +G E + K G T + + Sbjct: 1302 YMCEATNPSGKASKNFDIGIKGEAPTFASKLQPIQVTEEDECKLTCKVSGLPEPTIKWFK 1361 Query: 203 QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262 + V + T D K T ++ + E + V+ S ++D Sbjct: 1362 DGEPVK--SDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRS 1419 Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 V P +I K + + E AQF + + G P+P V W+ R+++ + +I Sbjct: 1420 VKP-EIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEWYHGPTRILDGGRFKI-------- 1470 Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382 S+S EN +V S + + T V D + Sbjct: 1471 --------SES------EENDMYSLVISNLIMDDLGTYKCVASN------DAGKATARVN 1510 Query: 383 IEISEKALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441 +++ EK P+F + + +V +G+ + G+P P+VTW+ + + +R+ N + L Sbjct: 1511 LDVKEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQ-L 1569 Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501 ++ +++ I T D G C A NK+G ++ + + V + PK + Sbjct: 1570 MSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGE----GPKLASELQPMQ 1625 Query: 502 VREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 V EG+ L+ GT P I W KDG P+ + ++ G L++ +DA Sbjct: 1626 VTEGDDCKLSCNVTEGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGD 1685 Query: 561 YQCTAQNVAGSTATRA 576 Y+ N G+ + A Sbjct: 1686 YEVEITNKFGTVKSSA 1701 Score = 89.8 bits (213), Expect = 5e-17 Identities = 62/250 (24%), Positives = 112/250 (44%), Gaps = 15/250 (6%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 PEF + +++ +G+ A SL+ G + WF +GK + S I+ Sbjct: 1231 PEFDKDEVEPIEVKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYS 1288 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 + I+ T D+GTY C ATN G+A + + KG+ P F + +Q I+ ++ + Sbjct: 1289 IRIVRTSPEDAGTYMCEATNPSGKASKNFDIGI----KGEAPTFASKLQPIQVTEEDE-C 1343 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 C V + +P +K W+ +G+P++ RIK D L D GEY Sbjct: 1344 KLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVT 1401 Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287 N +G T A ++ V S++P+ + K+ ++E+++ Q Q P + Sbjct: 1402 NNFGTVRTSADVD------VQKRSVKPEIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEW 1455 Query: 3288 IQDVTKLVEG 3297 T++++G Sbjct: 1456 YHGPTRILDG 1465 Score = 83.8 bits (198), Expect = 3e-15 Identities = 77/330 (23%), Positives = 137/330 (41%), Gaps = 44/330 (13%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 PEF +D+ +GQ AS + W +GKT+ +S RI Sbjct: 942 PEFIQTDTKPIDVEQGQ--DVTASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYE 999 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I + D+GTY+C ATN G+ + KG+ P ++ +Q ++ + + Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNV----KGEAPTLSSKLQPVQ-VTEEDDC 1054 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 C V + +P +K W+ +G+P++ RIK D L D GEY + Sbjct: 1055 KLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVT 1112 Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287 N +G T A I V +++P+ + K+ ++E+L+ Q + P + Sbjct: 1113 NNFGTVRTSADI------AVQRRNVKPEIVGKVHDIEALETEQARFDIPIKGYPKPVVEW 1166 Query: 3288 IQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYC 3347 T++++G F +L ++ D+ + +VI D++ Sbjct: 1167 FHGPTRILDG--GRF--KLSESEENDM----------------------YSLVISDLVM- 1199 Query: 3348 YEENSGEYECVATNKLGRDSTKANLKCTSK 3377 ++ G Y+CVA N G+ + +ANL K Sbjct: 1200 --DDLGTYKCVANNDAGKTTARANLDVKEK 1227 Score = 83.0 bits (196), Expect = 5e-15 Identities = 68/247 (27%), Positives = 106/247 (42%), Gaps = 19/247 (7%) Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAH-YEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY 3101 D +PP FT+ K + Q++ +EA L P IE+ +GK + + Sbjct: 643 DKQQPPTFTSEVKPVQANENEQVSVVFEADLTPDSK----IEFLKDGKPFKGDENSDYSF 698 Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEG 3160 ++L DSGTY C TNK GQ+ VK+ K K Q P F I Sbjct: 699 DGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITKPVV 758 Query: 3161 LKDGQSAH--FECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218 +K+ + FE V P D KIEW +G+P R D + L + T D Sbjct: 759 VKEKEQVKLVFEADVTP----DSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKD 814 Query: 3219 SGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPS 3278 +G Y C NKYG+ + + V + L+P+++ ++ +++++ Q + S Sbjct: 815 TGTYECVIANKYGKCSSPVDVK------VEPKHLKPEAVTPMKNIDAVESGQARFEVEVS 868 Query: 3279 AEP-PKF 3284 P PKF Sbjct: 869 GSPEPKF 875 Score = 78.6 bits (185), Expect = 1e-13 Identities = 98/394 (24%), Positives = 167/394 (42%), Gaps = 78/394 (19%) Query: 1812 SQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPY 1871 S ++ + S + + D+ + +AP F ++L P +++E C++ Sbjct: 1295 SPEDAGTYMCEATNPSGKASKNFDIGIK-GEAPTFASKLQ-PIQVTEEDECKLTCKVSGL 1352 Query: 1872 PDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931 P+P ++W+ +G+ ++S R + + D L + +D GEY + NN G +S Sbjct: 1353 PEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTS 1410 Query: 1932 IRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTE 1991 ++VQ + S + K+ +E AV+ E+ QF PIK Sbjct: 1411 ADVDVQKR------SVKPEIMGKVDDIE-------AVE-----TEQAQFDIPIK------ 1446 Query: 1992 GHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK--TTYDFGYVALDILYAYAEDTGT 2049 G+P PV VEWY + G RFK + + +L I +D GT Sbjct: 1447 GYP-------KPV------VEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGT 1493 Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRP 2109 Y C A+N G+A T+ V +D K ++ D + +PIE +Q G+ Sbjct: 1494 YKCVASNDAGKA--TARVNLDVKEKMFQPEFDRDEV------------EPIEVKQ-GEE- 1537 Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVAL 2169 A TSLE ++ P +T W+ +G+ +R + ++ Sbjct: 1538 ----ASTSLE-------------IQGKPKPKVT--WYKDGKVLRETRNIQLMSIGNTYSV 1578 Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203 I+ T +D GTYMC+ATNK G + +KV+G Sbjct: 1579 TIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSG 1612 Score = 73.3 bits (172), Expect = 4e-12 Identities = 119/484 (24%), Positives = 190/484 (39%), Gaps = 94/484 (19%) Query: 3039 QPDDDTGRPPEFT-TVFKDIVDISEGQIAH-YEASLIPTGDQSMVIEWFYNGKTIEASHR 3096 +P + + P F + K +V + Q+ +EA + P IEW +GK R Sbjct: 738 EPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTPDSK----IEWLKDGKPFTPDQR 793 Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ 3156 + ++ L + T D+GTY C NK+G+ V ++ + K KP T ++ Sbjct: 794 SDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKV--EPKHLKPEAVTPMK 851 Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV--SDFGFVVLDIAYT 3214 NI+ ++ GQ A FE V P+ K EWYH + S + K + D L I Sbjct: 852 NIDAVESGQ-ARFEVEVS--GSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENV 908 Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274 D G Y N G +A + K V E +Q D+ + ++ QG Q T Sbjct: 909 DTTDGGLYKLITSNLAGTTTNKAELKVKEK-EVAPEFIQTDT----KPIDVEQG-QDVTA 962 Query: 3275 STPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334 S PK VT L +G++ R+VP G Y Sbjct: 963 SFKIKSKPK-----PQVTWLKDGKTLSSSKRIVPT----------------VRGDTYE-- 999 Query: 3335 HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGL 3394 L I E++G Y C ATN +G KC+S + + + P + L Sbjct: 1000 -------LVIKKSTPEDTGTYTCTATNNIG--------KCSSDFTVNVKGEAPT-LSSKL 1043 Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454 + +Q E+ ++ K V +P I+ ++GE + R+ PT Sbjct: 1044 QPVQVTEE----------DDCKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPT------- 1086 Query: 3455 EWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514 ++GK+ C F + + +D GEY + NN+G T+A + VQ Sbjct: 1087 ---YDGKT----------CTLTFKGITM-----DDGGEYEVQVTNNFGTVRTSADIAVQ- 1127 Query: 3515 KRNI 3518 +RN+ Sbjct: 1128 RRNV 1131 Score = 68.9 bits (161), Expect = 9e-11 Identities = 52/214 (24%), Positives = 87/214 (40%), Gaps = 4/214 (1%) Query: 364 QDQRSQYITDTQQRETEERIEI-SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422 +D+ S + + E +++I +K P F + E + P + Sbjct: 619 KDEVSSFKLGAKPGEYTLQLDIPKDKQQPPTFTSEVKPVQANENEQVSVVFEADLTPDSK 678 Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 + + + + + D N + N L N T DSG CV NK G+++ ++ + Sbjct: 679 IEFLKDGKPFKGDENSDYSF-DGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITI 737 Query: 483 I-EKEQVVAPKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH 540 +KE+ AP F+ + + V+E E V L A TP +I W KDG P P+ Sbjct: 738 EPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTPDSKIEWLKDGKPFTPDQRSDYT 797 Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574 DG TL + D Y+C N G ++ Sbjct: 798 FDGRIITLMLKDTSVKDTGTYECVIANKYGKCSS 831 Score = 66.9 bits (156), Expect = 4e-10 Identities = 56/202 (27%), Positives = 87/202 (43%), Gaps = 10/202 (4%) Query: 3056 DIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF--GMVVLEILGT 3113 D ++ E + A ++ + G V+EW++ I R + + M L I Sbjct: 1429 DDIEAVETEQAQFDIPI--KGYPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNL 1486 Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTT-HIQNIEGLKDGQSAHFECT 3172 D GTY C A+N G+A V L+ K K +P F ++ IE +K G+ A Sbjct: 1487 IMDDLGTYKCVASNDAGKATARVNLDV--KEKMFQPEFDRDEVEPIE-VKQGEEASTSLE 1543 Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 + P K+ WY +G+ +R + I+ +S + I T D G Y+C A NK G Sbjct: 1544 IQ--GKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGT 1601 Query: 3233 DFTRATINCYGKGGVYLESLQP 3254 + I G+G LQP Sbjct: 1602 SSRKFDIKVSGEGPKLASELQP 1623 Score = 66.5 bits (155), Expect = 5e-10 Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 15/188 (7%) Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103 +G P+ + + + ++EG + + G +I+WF +G+ +++ HRI+ Y Sbjct: 1611 SGEGPKLASELQPM-QVTEGDDCKLSCN-VTEGTTKPIIKWFKDGEPVKSDHRIKPSYYG 1668 Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 +L + G D+G Y TNK+G + S ++ + + KP ++ +IE ++ Sbjct: 1669 KTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDV--QRRNVKPEIVGNVDDIEAVET 1726 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD-----FGFVVLDIAYTQNHD 3218 Q A F+ T+ P +EWYH + R K + V+ D+A D Sbjct: 1727 EQ-ARFDITIKGYPKP--VVEWYHGPTRILDGGRFKISESEENDMYSLVISDLAM---DD 1780 Query: 3219 SGEYVCRA 3226 G Y C A Sbjct: 1781 LGTYKCVA 1788 Score = 64.5 bits (150), Expect = 2e-09 Identities = 57/210 (27%), Positives = 88/210 (41%), Gaps = 11/210 (5%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF--GM 3105 PE DI + E + A ++ + G V+EWF+ I R + + M Sbjct: 1133 PEIVGKVHDI-EALETEQARFDIPI--KGYPKPVVEWFHGPTRILDGGRFKLSESEENDM 1189 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTT-HIQNIEGLKDG 3164 L I D GTY C A N G+ L+ K K +P F ++ IE +K G Sbjct: 1190 YSLVISDLVMDDLGTYKCVANNDAGKTTARANLDV--KEKMFQPEFDKDEVEPIE-VKQG 1246 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 + A ++V P ++ W+ +G+P+R S I+ S + I T D+G Y+C Sbjct: 1247 EEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMC 1304 Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQP 3254 A N G+ I G+ + LQP Sbjct: 1305 EATNPSGKASKNFDIGIKGEAPTFASKLQP 1334 Score = 60.5 bits (140), Expect = 3e-08 Identities = 46/196 (23%), Positives = 71/196 (36%), Gaps = 5/196 (2%) Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444 ++ K AP Q VTE + C+V+G P P + WF + ++ D K + Sbjct: 1030 VNVKGEAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPTY-D 1088 Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504 L +T+ D G N G + V + V P+ V + + E Sbjct: 1089 GKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRN--VKPEIVGKVHDIEALE 1146 Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT--DGGASTLDIPRAKASDAAWYQ 562 E + G P P + W I+ ++ + +L I D Y+ Sbjct: 1147 TEQARFDIPIKGYPKPVVEWFHGPTRILDGGRFKLSESEENDMYSLVISDLVMDDLGTYK 1206 Query: 563 CTAQNVAGSTATRARL 578 C A N AG T RA L Sbjct: 1207 CVANNDAGKTTARANL 1222 Score = 59.7 bits (138), Expect = 6e-08 Identities = 90/382 (23%), Positives = 150/382 (39%), Gaps = 30/382 (7%) Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877 D PK++ PP F +++K E+E V + D K IE+ ++GK Sbjct: 639 DIPKDK---QQPPTFTSEVKPVQANENEQVSVVFEADLTPDSK--IEFLKDGKPFKGDEN 693 Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT--KATISCKK----LPDIILQN 3931 +D + L +DSG Y C N G+ + K TI KK P I + Sbjct: 694 SDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEI 753 Query: 3932 QVPRGMKRSEALTQM-EATIKKYTSEVYLTEDDLYDVDKKQ----PPRFVTQIQSQTSLV 3986 P +K E + + EA + + +L + + D++ R +T + TS+ Sbjct: 754 TKPVVVKEKEQVKLVFEADVTPDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSV- 812 Query: 3987 EMETTKFECQLA-PVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSG- 4044 +T +EC +A G + V+ K L TP+ + V E SG Sbjct: 813 -KDTGTYECVIANKYGKCSSPVDVKVEPKH-LKPEAVTPMKNIDAVESGQARFEVEVSGS 870 Query: 4045 -----EYLCRATNLYGMDETKAVIKTTGKP-GIVYDSQLPKHMKSIEKIREMEASWQVTP 4098 E+ +T L D+ K +IK KP + + + K+ + T Sbjct: 871 PEPKFEWYHGSTKLNDSDKHK-IIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTN 929 Query: 4099 EQVVEESKARCPPVFVSL-PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY 4157 + ++ + P F+ + VE+G+ ++ PKP+V WL +G T+ + R Sbjct: 930 KAELKVKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSSSKRI 989 Query: 4158 KLTYDG-MYHFDIPKTRQYDTG 4178 T G Y I K+ DTG Sbjct: 990 VPTVRGDTYELVIKKSTPEDTG 1011 Score = 58.8 bits (136), Expect = 1e-07 Identities = 62/236 (26%), Positives = 97/236 (41%), Gaps = 39/236 (16%) Query: 904 ESTQKPEFKTPIKD-QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962 + Q P F + +K Q + E FEA L P DS ++E+LKDG+P + F Sbjct: 643 DKQQPPTFTSEVKPVQANENEQVSVVFEADLTP--DS--KIEFLKDGKPFKGDENSDYSF 698 Query: 963 NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022 + + L+ K+ T D+G Y C N GQ+++ +TI KK+ + Q P + +I Sbjct: 699 DGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKE---KKQAPVFIHEI-- 753 Query: 1023 LEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFN 1082 + +E+VK+ FEA V P S +EW + Sbjct: 754 ---TKPVVVKEKEQVKLV----------------------FEADVTPDS----KIEWLKD 784 Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 GK T R D + L + +D+G Y V N G+ + VE + Sbjct: 785 GKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK 840 Score = 58.8 bits (136), Expect = 1e-07 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 3/109 (2%) Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698 +QAP+F + + E + V L + + P+ KIEW K+G T R TFD Sbjct: 744 KQAPVFIHEITKPVVVKEKEQVKLVFEAD--VTPDSKIEWLKDGKPFTPDQRSDYTFDGR 801 Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHP 2747 ++TL + D+G Y C N G+ S +K+E +H L E++ P Sbjct: 802 IITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPKH-LKPEAVTP 849 Score = 58.4 bits (135), Expect = 1e-07 Identities = 69/335 (20%), Positives = 132/335 (39%), Gaps = 35/335 (10%) Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 GE +Q+ D+ P ++ KP + E F+ L+ P ++ + K+G+ Sbjct: 632 GEYTLQLDIPKDKQQPPTFTSEV--KPVQANENEQVSVVFEADLT--PDSKIEFLKDGKP 687 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365 + + L +N + DSG Y + N +G + + +E E + Sbjct: 688 FKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKE---KK 744 Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425 Q +I E + + + EK + VK+ + DVT ++ + G+P Sbjct: 745 QAPVFI-----HEITKPVVVKEK----EQVKLVFEADVTPD--SKIEWLKDGKP------ 787 Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485 F D++ ++ +I+ LM+ + ++ D+G CV NK G+ + + V K Sbjct: 788 FTPDQRSDYTFDGRIIT-------LMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK 840 Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI--HTDG 543 + P+ V ++ E G+P P+ W + + + +I D Sbjct: 841 H--LKPEAVTPMKNIDAVESGQARFEVEVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDK 898 Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 TL I +D Y+ N+AG+T +A L Sbjct: 899 PLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAEL 933 Score = 57.6 bits (133), Expect = 2e-07 Identities = 61/246 (24%), Positives = 105/246 (42%), Gaps = 39/246 (15%) Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ-SAHFECTVVPVDDPDMKIEWYHNGQP 3191 E +++L+ + K K Q P FT+ ++ ++ ++ Q S FE + PD KIE+ +G+P Sbjct: 633 EYTLQLD-IPKDKQQPPTFTSEVKPVQANENEQVSVVFEADLT----PDSKIEFLKDGKP 687 Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251 + D ++L DSG Y C NK+G+ + I + Sbjct: 688 FKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKI-----------T 736 Query: 3252 LQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDD 3311 ++P + ++Q P + + ++ KLV FEA + P Sbjct: 737 IEP------------KKEKKQAPVFIHEITKPVVVKEKEQVKLV------FEADVTP--- 775 Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371 D K+EW +GK R D I+ L + +++G YECV NK G+ S+ + Sbjct: 776 -DSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVD 834 Query: 3372 LKCTSK 3377 +K K Sbjct: 835 VKVEPK 840 Score = 57.2 bits (132), Expect = 3e-07 Identities = 67/274 (24%), Positives = 114/274 (41%), Gaps = 49/274 (17%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHL--EATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033 + P F +K + E V + EA LTP + ++E+ +G+P + ++D Sbjct: 646 QPPTFTSEVKPVQANENEQVSVVFEADLTPDS----KIEFLKDGKPFKGDENSDYSFDGR 701 Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEK 2093 + L A +D+GTY C TN G++ +S VK+ T++ ++ KK Sbjct: 702 NILLSFKNATQKDSGTYECVLTNKHGQS--SSDVKI---------TIEPKKEKK------ 744 Query: 2094 YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAH--FECRVEPINDPHLTIDWFHNGQK 2151 Q PVF+ +T +KE ++ FE V P + I+W +G+ Sbjct: 745 -------------QAPVFIHEITKPVVVKEKEQVKLVFEADVTPDSK----IEWLKDGKP 787 Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211 R T D + L + T +D+GTY C NK G+ + +KV Sbjct: 788 FTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPKH------ 841 Query: 2212 QHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRF 2244 P + ++ ++A + R EVE P+F Sbjct: 842 LKPEAVTPMKNIDAVESGQARFEVEVSGSPEPKF 875 Score = 56.8 bits (131), Expect = 4e-07 Identities = 70/312 (22%), Positives = 133/312 (42%), Gaps = 26/312 (8%) Query: 89 AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTA 148 A+F+ ++G P PVV W +++ ++ + +E+ SL+I + D G Y C A Sbjct: 1439 AQFDIPIKGYPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVA 1498 Query: 149 RNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTE-QSRQTQKV 207 N G+A V + + R E +E K + E Q + KV Sbjct: 1499 SNDAGKATARVNLDVKEKMFQPEFD------RDEVEPIEVKQGEEASTSLEIQGKPKPKV 1552 Query: 208 A-YTNGTDHSSTDDFKV----DTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262 Y +G T + ++ +T+ ++R Y+ E+ + T + Sbjct: 1553 TWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTP---DDVGTYMCEATNKAGTSSRKFDIK 1609 Query: 263 VSP--PKIAQKPRNSKLQEGADAQFQVQLS-GNPRPRVTWFKNGQRLINSNKHEIITTHN 319 VS PK+A + + ++ EG D + ++ G +P + WFK+G+ + + H I ++ Sbjct: 1610 VSGEGPKLASELQPMQVTEGDDCKLSCNVTEGTTKPIIKWFKDGEPV--KSDHRIKPSYY 1667 Query: 320 HTT--LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR 377 T L + +D+G Y + N G + +S + V+ V+ + + D + Sbjct: 1668 GKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQ---RRNVKPEIVGNVDDIEAV 1724 Query: 378 ETEE-RIEISEK 388 ETE+ R +I+ K Sbjct: 1725 ETEQARFDITIK 1736 Score = 55.6 bits (128), Expect = 9e-07 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 +AP S L ++ E + L C++ + + T ++WF +G+P+K+ R +P Y+ Sbjct: 1035 EAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTC 1092 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + +D G Y Q TN G TS + V Sbjct: 1093 TLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAV 1126 Score = 55.2 bits (127), Expect = 1e-06 Identities = 49/167 (29%), Positives = 80/167 (47%), Gaps = 15/167 (8%) Query: 1709 QAPVFTMPM-KDIRVAENQAAH--FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765 QAPVF + K + V E + FEA + P D K +EWL++G P R D Sbjct: 745 QAPVFIHEITKPVVVKEKEQVKLVFEADVTP--DSK--IEWLKDGKPFTPDQRSDYTFDG 800 Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825 + L +K + +D+GTY C N+ G+ + + V+ K L+ + + ++ I +E Sbjct: 801 RIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK---HLKPEAVTPMKNIDAVE 857 Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872 Q R +VEV+ + P+F +G TKL++ H + E P Sbjct: 858 SG---QARFEVEVSGSPEPKF-EWYHGSTKLNDSDK-HKIIKAEDKP 899 Score = 55.2 bits (127), Expect = 1e-06 Identities = 39/121 (32%), Positives = 55/121 (45%), Gaps = 6/121 (4%) Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231 I P F L P V+E L C++ + +PT ++WF +G V R K YD Sbjct: 1321 IKGEAPTFASKLQ-PIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYD 1377 Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS---DIVTDTQNEQAIEQI 1288 L T D GEY V N+ G+ TSA V V +RS +I+ + +A+E Sbjct: 1378 GKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMGKVDDIEAVETE 1437 Query: 1289 Q 1289 Q Sbjct: 1438 Q 1438 Score = 55.2 bits (127), Expect = 1e-06 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 2/106 (1%) Query: 1298 TKQVREDITVM-QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356 T + DI V + P+ + L ++ EG + L C + G ++WF +G+P+K+ Sbjct: 1601 TSSRKFDIKVSGEGPKLASELQPMQVTEGDDCKLSCNVTE-GTTKPIIKWFKDGEPVKSD 1659 Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 HR +P+Y L+L V D+G Y + TN+ G +S + V Sbjct: 1660 HRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDV 1705 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 +AP F+ L I+ E L C++ + + T ++WF +G+P+K+ R +P Y+ Sbjct: 1324 EAPTFASKLQPIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTC 1381 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + +D G Y + TN G TS + V Sbjct: 1382 TLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDV 1415 Score = 54.4 bits (125), Expect = 2e-06 Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 7/119 (5%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP FI P + +GQ +I+ P P +V W +GK L S R + Sbjct: 941 APEFIQTDTKPIDVEQGQDVTASFKIKSKPKP--QVTWLKDGKTLSSSKRIVPTVRGDTY 998 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 L I ED+G YTC A NN+G+ S +NV+ + + S L+ +Q E+D Sbjct: 999 ELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEAPTL-----SSKLQPVQVTEED 1052 Score = 54.0 bits (124), Expect = 3e-06 Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 10/127 (7%) Query: 1186 PPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSA 1245 P V+E + L C++ + +PT ++WF +G V R K YD L T Sbjct: 1045 PVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMD 1102 Query: 1246 DTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDI 1305 D GEY V+ N+ G+ TSA + ++R ++ + + + I+ LE T+Q R DI Sbjct: 1103 DGGEYEVQVTNNFGTVRTSADI-AVQRRNVKPEIVGK--VHDIEALE-----TEQARFDI 1154 Query: 1306 TVMQAPQ 1312 + P+ Sbjct: 1155 PIKGYPK 1161 Score = 54.0 bits (124), Expect = 3e-06 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 9/151 (5%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 +AP F ++ I+V E ++ G P+ ++W ++G P+++ R+ +D Sbjct: 1324 EAPTFASKLQPIQVTEEDECKLTCKVS--GLPEPTIKWFKDGEPVKSDLRIKPTYDGKTC 1381 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828 L K + +D G Y N G TS+ + VQ K S++ E + K+ +E Sbjct: 1382 TLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQ-KRSVKPE-----IMGKVDDIEAVE 1435 Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859 Q + D+ + P + +GPT++ +G Sbjct: 1436 TEQAQFDIPIKGYPKP-VVEWYHGPTRILDG 1465 Score = 53.6 bits (123), Expect = 4e-06 Identities = 59/250 (23%), Positives = 105/250 (42%), Gaps = 44/250 (17%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 +AP ++L P +++E C++ P+P ++W+ +G+ ++S R + + D Sbjct: 1035 EAPTLSSKLQ-PVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1091 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 L + +D GEY + NN G +S + VQ R + + K+ +E Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQ------RRNVKPEIVGKVHDIE-- 1143 Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021 + E+ +F PIK G+P PV VEW+ + Sbjct: 1144 ----------ALETEQARFDIPIK------GYP-------KPV------VEWFHGPTRIL 1174 Query: 2022 QGHRFK--TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDT 2079 G RFK + + +L I +D GTY C A N G+ TT+ +D K ++ Sbjct: 1175 DGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGK--TTARANLDVKEKMFQPE 1232 Query: 2080 LDEQRLKKIQ 2089 D+ ++ I+ Sbjct: 1233 FDKDEVEPIE 1242 Score = 53.2 bits (122), Expect = 5e-06 Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 4/104 (3%) Query: 2635 DTGVQ-QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693 D G++ +AP F + L+ ++ E L +V +P +K WFK+G + + R+K Sbjct: 1318 DIGIKGEAPTFASKLQPI-QVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKP 1374 Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 T+D TL+ + DD G Y + TN G ++A + ++ R Sbjct: 1375 TYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKR 1418 Score = 52.0 bits (119), Expect = 1e-05 Identities = 32/151 (21%), Positives = 67/151 (44%), Gaps = 9/151 (5%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 +AP + ++ ++V E ++ G P+ ++W ++G P+++ R+ +D Sbjct: 1035 EAPTLSSKLQPVQVTEEDDCKLTCKVS--GLPEPTIKWFKDGEPVKSDLRIKPTYDGKTC 1092 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828 L K + +D G Y + N G TS+ + VQ + + + K+ +E Sbjct: 1093 TLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRR------NVKPEIVGKVHDIEALE 1146 Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859 Q R D+ + P + +GPT++ +G Sbjct: 1147 TEQARFDIPIKGYPKP-VVEWFHGPTRILDG 1176 Score = 52.0 bits (119), Expect = 1e-05 Identities = 56/229 (24%), Positives = 91/229 (39%), Gaps = 39/229 (17%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY--DFGY 2034 KP+ + + E E + + P VEW+ + G RFK + + Sbjct: 1132 KPEIVGKVHDIEALETEQARFDIPIKGYPKPV--VEWFHGPTRILDGGRFKLSESEENDM 1189 Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094 +L I +D GTY C A N G+ TT+ +D K ++ D+ E+E Sbjct: 1190 YSLVISDLVMDDLGTYKCVANNDAGK--TTARANLDVKEKMFQPEFDKD------EVE-- 1239 Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154 PIE +K+G+ A + P +T WF +G+ +R Sbjct: 1240 ----PIE-------------------VKQGEEASTSLVIRGKPKPEVT--WFKDGKPLRE 1274 Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203 + ++ I+ T ED+GTYMC+ATN G+A + + G Sbjct: 1275 SKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKG 1323 Score = 52.0 bits (119), Expect = 1e-05 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 6/107 (5%) Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028 K + P F +++Q + E + K C+++ + +P +K WF +G+P+ R P YD Sbjct: 1322 KGEAPTFASKLQP-IQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDG 1378 Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGIV 4072 + F + +D GEY TN +G T A V K + KP I+ Sbjct: 1379 KTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIM 1425 Score = 51.6 bits (118), Expect = 2e-05 Identities = 43/144 (29%), Positives = 66/144 (45%), Gaps = 12/144 (8%) Query: 904 ESTQKPEFKTPIKDQISIKEGGFAH--FEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 E Q P F I + +KE FEA + P DS ++EWLKDG+P R Sbjct: 742 EKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTP--DS--KIEWLKDGKPFTPDQRSDYT 797 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021 F+ + L +K +V D G Y C N G+ ++ ++ V K + E+ P ++ I Sbjct: 798 FDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVK-VEPKHLKPEAVTP--MKNID 854 Query: 1022 YLEDASRYSKRTEEEVKITQKPRF 1045 +E R E EV + +P+F Sbjct: 855 AVESG---QARFEVEVSGSPEPKF 875 Score = 50.8 bits (116), Expect = 3e-05 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMK 1773 T P+ D+ ++ A F+ + PK +V WL++G + +S R+ L +K Sbjct: 949 TKPI-DVEQGQDVTASFKIK----SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIK 1003 Query: 1774 YVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806 PED+GTYTC A N +G+ + T+ V+ +A Sbjct: 1004 KSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEA 1036 Score = 50.8 bits (116), Expect = 3e-05 Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 40/198 (20%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 ++W KDG PV++ RI ++ LT K +T+ D G Y N G TSA++ V Sbjct: 1357 IKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVD-V 1415 Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062 K+ + E G ++ I+ +E T++ +F P+KG K V Sbjct: 1416 QKRSVKPEIM--GKVDDIEAVE---------------TEQAQFDIPIKGYPKPV------ 1452 Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHDFGYVALDIASVRAEDSGVYTVVA 1120 VEWY +I R I + +L I+++ +D G Y VA Sbjct: 1453 --------------VEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVA 1498 Query: 1121 RNAAGEAQLSASMTVETR 1138 N AG+A ++ V+ + Sbjct: 1499 SNDAGKATARVNLDVKEK 1516 Score = 50.4 bits (115), Expect = 3e-05 Identities = 45/143 (31%), Positives = 64/143 (44%), Gaps = 20/143 (13%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F S L I E D C V +PT+K WF + +P+ S R K T+D +L Sbjct: 1328 FASKLQPIQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTF 1385 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQ--GKA-GLEAVEQAEE 2892 +D G Y + TN+ G+ TS D ++ + P+ GK +EAVE E+ Sbjct: 1386 KGITMDDGGEYEVEVTNNFGTVRTS------ADVDVQKRSVKPEIMGKVDDIEAVE-TEQ 1438 Query: 2893 ARLAKGRRPSVPDTEYPKP--EW 2913 A+ +P YPKP EW Sbjct: 1439 AQF------DIPIKGYPKPVVEW 1455 Score = 50.4 bits (115), Expect = 3e-05 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 I++ + + P+ V D + E + RFD + G P P V W+ +I D KI Sbjct: 1703 IDVQRRNVKPEIVGNVDDIEAVETEQARFDITIKGYPKPVVEWYHGPTRILDGGRFKISE 1762 Query: 443 NESGN-HALMITNVTLSDSGVVTCVA 467 +E + ++L+I+++ + D G CVA Sbjct: 1763 SEENDMYSLVISDLAMDDLGTYKCVA 1788 Score = 50.0 bits (114), Expect = 5e-05 Identities = 60/214 (28%), Positives = 90/214 (42%), Gaps = 26/214 (12%) Query: 902 VPESTQKPEFKTPIKDQISIKEGG--FAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT 959 V E PEF I +++G A F+ + +P +V WLKDG+ + +S RI Sbjct: 935 VKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIKSKP----KPQVTWLKDGKTLSSSKRIV 990 Query: 960 TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEK 1019 L IK T D G YTC A N IG+ S++ T+ K + S L+ Sbjct: 991 PTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKC--SSDFTVNVKGEAPTLSSK---LQP 1045 Query: 1020 IQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEW 1079 +Q E E++ K+T K L P +G+ + R++P D T Sbjct: 1046 VQVTE---------EDDCKLTCKVSGL-PEPTIKWFKDGEPVKSDLRIKPTYD-GKTCTL 1094 Query: 1080 YFNGKQITSAN--RIQTYHDFGYV--ALDIASVR 1109 F G + +Q ++FG V + DIA R Sbjct: 1095 TFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQR 1128 Score = 50.0 bits (114), Expect = 5e-05 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 4/108 (3%) Query: 2641 APIFT-THLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 AP F T K D + +GQ V +++ + P ++ W K+G TL++ R+ T Sbjct: 941 APEFIQTDTKPID-VEQGQDVTASFKIKSKPKP--QVTWLKDGKTLSSSKRIVPTVRGDT 997 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHP 2747 L I +D+G YTC ATN +G+ S ++ ++ L L P Sbjct: 998 YELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEAPTLSSKLQP 1045 Score = 49.6 bits (113), Expect = 6e-05 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 3/99 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +AP ++ L+ ++ E L +V +P +K WFK+G + + R+K T+D Sbjct: 1035 EAPTLSSKLQPV-QVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKT 1091 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738 TL+ + DD G Y + TN G ++A I ++ R+ Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRN 1130 Score = 49.6 bits (113), Expect = 6e-05 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 10/142 (7%) Query: 1171 EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY 1230 ++S P L P V+EG + L C + G ++WF +G V R K Y Sbjct: 1609 KVSGEGPKLASELQ-PMQVTEGDDCKLSCNVTE-GTTKPIIKWFKDGEPVKSDHRIKPSY 1666 Query: 1231 DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290 L++ T AD G+Y V N G+ +SA + V R+ N IE ++ Sbjct: 1667 YGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRNVKPEIVGNVDDIEAVE- 1725 Query: 1291 LEDAARRTKQVREDITVMQAPQ 1312 T+Q R DIT+ P+ Sbjct: 1726 -------TEQARFDITIKGYPK 1740 Score = 49.2 bits (112), Expect = 8e-05 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 6/102 (5%) Query: 763 EEQTSQRPQFIRPLQDLGELQEGRNAH--FEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820 +++ Q P FI + ++E FEA +TP S ++EW KDG+P T R Sbjct: 740 KKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTPDS----KIEWLKDGKPFTPDQRSD 795 Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 F+ ++L + +D G+Y NK G+ S ++V Sbjct: 796 YTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKV 837 Score = 49.2 bits (112), Expect = 8e-05 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 6/107 (5%) Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028 K + P +++Q + E + K C+++ + +P +K WF +G+P+ R P YD Sbjct: 1033 KGEAPTLSSKLQP-VQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDG 1089 Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETK---AVIKTTGKPGIV 4072 + F + +D GEY + TN +G T AV + KP IV Sbjct: 1090 KTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRNVKPEIV 1136 Score = 49.2 bits (112), Expect = 8e-05 Identities = 42/139 (30%), Positives = 62/139 (44%), Gaps = 16/139 (11%) Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837 S L + E D+ C V +PT+K WF + +P+ S R K T+D +L Sbjct: 1041 SKLQPVQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKG 1098 Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKA-GLEAVEQAEEARLA 2896 +D G Y + TN+ G+ TS + +N+ GK +EA+E E+AR Sbjct: 1099 ITMDDGGEYEVQVTNNFGTVRTSADI-AVQRRNV---KPEIVGKVHDIEALE-TEQARF- 1152 Query: 2897 KGRRPSVPDTEYPKP--EW 2913 +P YPKP EW Sbjct: 1153 -----DIPIKGYPKPVVEW 1166 Score = 48.8 bits (111), Expect = 1e-04 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 6/99 (6%) Query: 1709 QAPVFTMPMKDIRVAENQAAH--FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 Q P FT +K ++ EN+ FEA L P D K +E+L++G P + D Sbjct: 646 QPPTFTSEVKPVQANENEQVSVVFEADLTP--DSK--IEFLKDGKPFKGDENSDYSFDGR 701 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 + L+ K +DSGTY C N+ G++ + + ++ K Sbjct: 702 NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPK 740 Score = 48.4 bits (110), Expect = 1e-04 Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 4/104 (3%) Query: 1293 DAARRTKQVREDITV-MQAPQFSR-ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350 DA + T + D+ M P+F + + IE +G ++ G V WF +G Sbjct: 1212 DAGKTTARANLDVKEKMFQPEFDKDEVEPIEVKQGEEASTSLVIR--GKPKPEVTWFKDG 1269 Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEA 1394 KP++ + D ++ ++ PED+G Y C+ATN G+A Sbjct: 1270 KPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKA 1313 Score = 48.4 bits (110), Expect = 1e-04 Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 11/153 (7%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 G+ P F + L ++ + E D C+V + +P TI WF +G+ +++ R + T+D Sbjct: 1323 GEAPTFASKLQPIQ-VTEEDECKLTCKVSGLPEP--TIKWFKDGEPVKSDLRIKPTYDGK 1379 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225 L +D G Y + TN G T++ + ++ + P + K+ +EA Sbjct: 1380 TCTLTFKGITMDDGGEYEVEVTNNFG------TVRTSADVDVQKRSVKPEIMGKVDDIEA 1433 Query: 2226 QGHSTRIEVEEPKISPPRFVTE-LRGTTHVFEG 2257 + + + + P P+ V E G T + +G Sbjct: 1434 V-ETEQAQFDIPIKGYPKPVVEWYHGPTRILDG 1465 Score = 48.4 bits (110), Expect = 1e-04 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 3/106 (2%) Query: 768 QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827 + P F LQ + ++ E +++ + +PT ++W+KDG P+ + RI ++ Sbjct: 1324 EAPTFASKLQPI-QVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1380 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLG 873 +L + +D G Y V N G ++A + V RS +G Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMG 1426 Score = 48.0 bits (109), Expect = 2e-04 Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 9/132 (6%) Query: 3525 PKGMEGTID-KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENS--SAHFECRL 3581 PKG + K+ A G T+ P+ + PP FT+ + +EN S FE L Sbjct: 616 PKGKDEVSSFKLGAKPG-EYTLQLDIPK-DKQQPPTFTSEVKPVQANENEQVSVVFEADL 673 Query: 3582 IPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA 3641 P DS ++E+ +GKP D ++L Q+D+G Y C TN+HG++ Sbjct: 674 TP--DS--KIEFLKDGKPFKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQS 729 Query: 3642 TVSCKLQVKGRQ 3653 + K+ ++ ++ Sbjct: 730 SSDVKITIEPKK 741 Score = 48.0 bits (109), Expect = 2e-04 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 8/147 (5%) Query: 1149 GLYE---KTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMG 1205 G YE +H + S V+ + ++ K PVF+ ++ P V E + + L E Sbjct: 716 GTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITKPVVVKEKEQVKLV--FEADV 773 Query: 1206 DPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265 P ++EW +G+ T R +D + L + + DTG Y N G + Sbjct: 774 TPDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPV 833 Query: 1266 IVRVIE---RSDIVTDTQNEQAIEQIQ 1289 V+V + + VT +N A+E Q Sbjct: 834 DVKVEPKHLKPEAVTPMKNIDAVESGQ 860 Score = 48.0 bits (109), Expect = 2e-04 Identities = 58/227 (25%), Positives = 90/227 (39%), Gaps = 37/227 (16%) Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493 D+ E +KP VT K+I+ V GQ FE ++ + K EW+ + + Sbjct: 834 DVKVEPKHLKPEAVTPMKNIDAVESGQ-ARFEVEVSGSPEP--KFEWYHGSTKLNDSDKH 890 Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLE 1553 + I AED +YT N+ TD +L T+++ +T N+A L+ Sbjct: 891 KIIK-------------AEDKPLYTLIIENVDTTDGGLYKLI---TSNLAGTTTNKAELK 934 Query: 1554 QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEW 1613 V E T K +++++GQ ++ S +V W Sbjct: 935 ----------------VKEKEVAPEFIQTDTKPIDVEQGQDVTASFKI--KSKPKPQVTW 976 Query: 1614 YHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 + K L S R T L I PED+GTYTC A N +G+ Sbjct: 977 LKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGK 1023 Score = 48.0 bits (109), Expect = 2e-04 Identities = 43/163 (26%), Positives = 75/163 (46%), Gaps = 12/163 (7%) Query: 2216 GLEKIRQLEAQGHSTR---IEVEEPKISPPRFVTELRGTTHVFEGK--TAHFECQVEPVH 2270 GL K+ G +T ++V+E +++P T+ + V +G+ TA F+ + +P Sbjct: 914 GLYKLITSNLAGTTTNKAELKVKEKEVAPEFIQTDTK-PIDVEQGQDVTASFKIKSKP-- 970 Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330 ++ + +GK L S+ R T L I+ PED G Y+ A N +G C+S Sbjct: 971 --KPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKCSS-- 1026 Query: 2331 SMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTR 2373 TV KG + S + + ++ E + K +PEP + Sbjct: 1027 DFTVNVKGEAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIK 1069 Score = 48.0 bits (109), Expect = 2e-04 Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F ++++ V E + + C+V +P I+W+++G+ + S R + YD +L Sbjct: 1326 PTFASKLQPIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTL 1383 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 + +D GEY N+FG T A + +K Sbjct: 1384 TFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQK 1417 Score = 48.0 bits (109), Expect = 2e-04 Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 43/223 (19%) Query: 2373 RQRPVFTQPLQNIDNIQ--EGQTAHFDCRLIPV-GDPTLKVEWFRNEKLIEDSSR--ITK 2427 ++R V + + +D+I+ E + A FD IP+ G P VEW+ I D R I++ Sbjct: 1416 QKRSVKPEIMGKVDDIEAVETEQAQFD---IPIKGYPKPVVEWYHGPTRILDGGRFKISE 1472 Query: 2428 THDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKI 2487 + + S+ IS++ +D G Y C ASN G+ + L+ + Sbjct: 1473 SEENDMYSLVISNLIMDDLGTYKCVASNDAGK----------ATARVNLDVK-------- 1514 Query: 2488 QKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYIN 2547 +K+ QP E DR+ +PI E+ +G+ A + G P + WY + Sbjct: 1515 EKMFQP------EFDRDEVEPI---------EVKQGEEASTSLEI--QGKPKPKVTWYKD 1557 Query: 2548 GVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G L+ + ++ I +D G YMC+A N+AG Sbjct: 1558 GKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAG 1600 Score = 47.6 bits (108), Expect = 2e-04 Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 12/168 (7%) Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750 K P F +++ I V E C+V + +PT++ WF +G P + R+ D Sbjct: 1322 KGEAPTFASKLQP-IQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDG 1378 Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810 L I D GEY TN +G+ T+A + D+ S P+ M K+ + Sbjct: 1379 KTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADV------DVQKRSVKPEIMG--KVDD 1430 Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKED 3858 +E A + PI P + T +G RF+ + D Sbjct: 1431 IEAVETEQAQFDIPIKGYPKPVVEWYHGPT-RILDGGRFKISESEEND 1477 Score = 47.6 bits (108), Expect = 2e-04 Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 10/124 (8%) Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475 KG+AP F L I+ E E +++ +P +K W+ +G+ +K+ R + D Sbjct: 1322 KGEAPTFASKLQPIQVTEEDE-CKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDG 1378 Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKI 3535 L +D GEY NN+G T+A + VQ KR++ E + G +D I Sbjct: 1379 KTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQ-KRSVKPE------IMGKVDDI 1431 Query: 3536 AALE 3539 A+E Sbjct: 1432 EAVE 1435 Score = 47.6 bits (108), Expect = 2e-04 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 2/101 (1%) Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825 + + P+ LQ + ++ EG + +T + + ++W+KDG P+ + RI + Sbjct: 1611 SGEGPKLASELQPM-QVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYG 1668 Query: 826 GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866 LN+ + DAG Y V NK G S+A I V R+ Sbjct: 1669 KTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN 1709 Score = 47.2 bits (107), Expect = 3e-04 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 3/109 (2%) Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 ++ I +K PP FT E+K + E V + P +I++ +G+PF Sbjct: 637 QLDIPKDKQQPPTFTSEVKP-VQANENEQVSVVFEADLT--PDSKIEFLKDGKPFKGDEN 693 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792 D I L +D+G Y C TNK G +++ KIT K++ Sbjct: 694 SDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKE 742 Score = 47.2 bits (107), Expect = 3e-04 Identities = 68/268 (25%), Positives = 100/268 (37%), Gaps = 47/268 (17%) Query: 3684 EITIED--EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 +ITIE EK P F EI + V E V + P +I+W +G+PF Sbjct: 734 KITIEPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVT--PDSKIEWLKDGKPFTPD 791 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801 R D I L + +D G Y C NK+G CS+ D+ +E P+ Sbjct: 792 QRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGK--------CSSPVDVKVE---PK 840 Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861 + E + TP K I + ES RFE V +PK Sbjct: 841 HLKPEAV-------------------TPMKNIDAV------ESGQARFEVEVSGSPEPK- 874 Query: 3862 RIEWYRNGKLLPSGHRYRTV--YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 EWY L +++ + D +L I V D G Y N G KA + Sbjct: 875 -FEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAEL 933 Query: 3920 SCKK---LPDIILQNQVPRGMKRSEALT 3944 K+ P+ I + P +++ + +T Sbjct: 934 KVKEKEVAPEFIQTDTKPIDVEQGQDVT 961 Score = 46.8 bits (106), Expect = 4e-04 Identities = 51/218 (23%), Positives = 87/218 (39%), Gaps = 36/218 (16%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 Q P F+ + ++ E V + D ++E+ +GKP K +++ + Sbjct: 646 QPPTFTSEVKPVQANENEQVSVVFEADLTPDS--KIEFLKDGKPFKGDENSDYSFDGRNI 703 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428 L + +DSG Y C TN+ G++ + + + KK+ + Q P + +I Sbjct: 704 LLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKE---KKQAPVFIHEI------- 753 Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488 KP V + ++ V FE + P DS K+EW K+G+P T Sbjct: 754 -------------TKPVVVKEKEQVKLV-------FEADVTP--DS--KIEWLKDGKPFT 789 Query: 1489 IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 R D + L + D +D+G Y C N G Sbjct: 790 PDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYG 827 Score = 46.8 bits (106), Expect = 4e-04 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 5/86 (5%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFG 2432 +P P++NID ++ GQ A F+ + G P K EW+ + DS + I K D Sbjct: 843 KPEAVTPMKNIDAVESGQ-ARFEVEVS--GSPEPKFEWYHGSTKLNDSDKHKIIKAEDKP 899 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458 ++ I +V D G+Y SNL G Sbjct: 900 LYTLIIENVDTTDGGLYKLITSNLAG 925 Score = 46.4 bits (105), Expect = 6e-04 Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 13/154 (8%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 G+ P + L ++ +E D C+V + +P TI WF +G+ +++ R + T+D Sbjct: 1034 GEAPTLSSKLQPVQVTEEDD-CKLTCKVSGLPEP--TIKWFKDGEPVKSDLRIKPTYDGK 1090 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225 L +D G Y + TN G + + V RN+ P + K+ +EA Sbjct: 1091 TCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQ-RRNV-----KPEIVGKVHDIEA 1144 Query: 2226 -QGHSTRIEVEEPKISPPRFVTE-LRGTTHVFEG 2257 + R ++ P P+ V E G T + +G Sbjct: 1145 LETEQARFDI--PIKGYPKPVVEWFHGPTRILDG 1176 Score = 46.0 bits (104), Expect = 8e-04 Identities = 32/105 (30%), Positives = 53/105 (50%), Gaps = 6/105 (5%) Query: 2632 MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691 + + +++AP FT+ L+ K G+ V L +V +D KI+ +K+G + RL Sbjct: 6 LIIAPAIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL 63 Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 D + L+ + DSG Y C TN G++ S A+I IE+ Sbjct: 64 ----DGENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEE 104 Score = 46.0 bits (104), Expect = 8e-04 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+FI+ ++++G++ A S P +V W KDG+ +++S RI Sbjct: 942 PEFIQTDTKPIDVEQGQDV--TASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYE 999 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 L I ED G+YT A N +G+ S ++ V Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNV 1032 Score = 46.0 bits (104), Expect = 8e-04 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 5/101 (4%) Query: 1726 QAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785 Q L+ G PK V W ++G P+ S + ++ + +PED+GTY C Sbjct: 1245 QGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMC 1304 Query: 1786 RAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLED 1826 A N G+A + + ++ +A S LQ IQ E+ Sbjct: 1305 EATNPSGKASKNFDIGIKGEA-----PTFASKLQPIQVTEE 1340 Score = 46.0 bits (104), Expect = 8e-04 Identities = 33/152 (21%), Positives = 68/152 (44%), Gaps = 12/152 (7%) Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433 + P F LQ I +E + C++ + +PT ++WF++ + ++ RI T+D Sbjct: 1324 EAPTFASKLQPIQVTEEDE-CKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1380 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLE-- 2491 ++T + +D G Y +N G +Q + PE M K+ +E Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFG------TVRTSADVDVQKRSVKPEIMGKVDDIEAV 1434 Query: 2492 QPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523 + + + + P + + KP+ + GP+ + +G Sbjct: 1435 ETEQAQFDIPIKGYPKPV-VEWYHGPTRILDG 1465 Score = 45.6 bits (103), Expect = 0.001 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 5/100 (5%) Query: 3280 EPPKFITQIQDVTKLVEGQ-SAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338 +PP F ++++ V Q S FEA L P D K+E+ +GK D Sbjct: 646 QPPTFTSEVKPVQANENEQVSVVFEADLTP----DSKIEFLKDGKPFKGDENSDYSFDGR 701 Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 ++L +++SG YECV TNK G+ S+ + K+ Sbjct: 702 NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKK 741 Score = 45.6 bits (103), Expect = 0.001 Identities = 56/249 (22%), Positives = 106/249 (42%), Gaps = 44/249 (17%) Query: 1026 ASRYSKRTEE-EVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081 A++Y K + +VK+ K P + P+K + + GQ A FE V + EWY Sbjct: 823 ANKYGKCSSPVDVKVEPKHLKPEAVTPMKNIDAVESGQ-ARFEVEVSGSPEPKF--EWYH 879 Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141 ++ +++ H ++AED +YT++ N + Sbjct: 880 GSTKLNDSDK----HKI---------IKAEDKPLYTLIIEN------------------V 908 Query: 1142 DTSSIHRGLYEK-TRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECR 1200 DT+ GLY+ T ++ + + +++E + P F+Q + P V +G+++ + Sbjct: 909 DTTD--GGLYKLITSNLAGTTTNKAELKVKE-KEVAPEFIQTDTKPIDVEQGQDVTASFK 965 Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260 ++ P +V W +G++++ R L I +T DTG YT A N++G Sbjct: 966 IK--SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGK 1023 Query: 1261 AHTSAIVRV 1269 + V V Sbjct: 1024 CSSDFTVNV 1032 Score = 45.6 bits (103), Expect = 0.001 Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 2/94 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P ++++ V E + + C+V +P I+W+++G+ + S R + YD +L Sbjct: 1037 PTLSSKLQPVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTL 1094 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 + +D GEY + N+FG T A I+ ++ Sbjct: 1095 TFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQR 1128 Score = 45.6 bits (103), Expect = 0.001 Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 3/105 (2%) Query: 1977 KPQFGKP-IKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 +P+F K ++ EV +G +L P V W+ +G+P+++ + Sbjct: 1230 QPEFDKDEVEPIEVKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTY 1287 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL 2080 ++ I+ ED GTYMC+ATN G+A + + ++ + L Sbjct: 1288 SIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKGEAPTFASKL 1332 Score = 45.2 bits (102), Expect = 0.001 Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 3/99 (3%) Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698 QQ P FT+ +K ++ + E P+ KIE+ K+G +FD Sbjct: 645 QQPPTFTSEVKPVQA---NENEQVSVVFEADLTPDSKIEFLKDGKPFKGDENSDYSFDGR 701 Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 + LS + DSG Y C TN G++ S I IE + Sbjct: 702 NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPK 740 Score = 45.2 bits (102), Expect = 0.001 Identities = 24/99 (24%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Query: 768 QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827 + P LQ + ++ E + +++ + +PT ++W+KDG P+ + RI ++ Sbjct: 1035 EAPTLSSKLQPV-QVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1091 Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866 +L + +D G Y V+ N G ++A I V R+ Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRN 1130 Score = 45.2 bits (102), Expect = 0.001 Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 2/113 (1%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E +PEF + I +K+G A + G V W KDG+P+ S I Sbjct: 1224 VKEKMFQPEFDKDEVEPIEVKQGEEASTSLVIR--GKPKPEVTWFKDGKPLRESKNIQQK 1281 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014 ++ I + DAG Y C A N G+A+ + ++ I + A P Sbjct: 1282 SIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKGEAPTFASKLQP 1334 Score = 45.2 bits (102), Expect = 0.001 Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 2/92 (2%) Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629 V E Q ++ +E+K+G+ A L+ +V W+ + KPL+ + Sbjct: 1224 VKEKMFQPEFDKDEVEPIEVKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQK 1281 Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 + ++ I+ PED+GTY C A N G+A Sbjct: 1282 SIGDTYSIRIVRTSPEDAGTYMCEATNPSGKA 1313 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Query: 1310 APQFSRA-LHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 AP+F + I+ +G +V +++ +V W +GK + + R P D Sbjct: 941 APEFIQTDTKPIDVEQGQDVTASFKIK--SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTY 998 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + PED+G YTC ATN +G+ + + V Sbjct: 999 ELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNV 1032 Score = 44.8 bits (101), Expect = 0.002 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 3/94 (3%) Query: 3830 PKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 P+FI T K VE+ + V +++ K PK ++ W ++GK L S R Sbjct: 942 PEFIQTDTKPIDVEQGQDVTASFKIKSK--PKPQVTWLKDGKTLSSSKRIVPTVRGDTYE 999 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922 L I ED+G Y C A N+ G+ + T++ K Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVK 1033 Score = 44.8 bits (101), Expect = 0.002 Identities = 32/155 (20%), Positives = 68/155 (43%), Gaps = 12/155 (7%) Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430 V + P + LQ + + E C++ + +PT ++WF++ + ++ RI T+D Sbjct: 1032 VKGEAPTLSSKLQPVQ-VTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYD 1088 Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKL 2490 ++T + +D G Y + +N G +Q PE + K+ + Sbjct: 1089 GKTCTLTFKGITMDDGGEYEVQVTNNFG------TVRTSADIAVQRRNVKPEIVGKVHDI 1142 Query: 2491 E--QPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523 E + + R + P + + KP+ + GP+ + +G Sbjct: 1143 EALETEQARFDIPIKGYPKPV-VEWFHGPTRILDG 1176 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 2/102 (1%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828 +P+F + + E+++G A L P V W+KDG+P+ S I Sbjct: 1230 QPEFDKDEVEPIEVKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTY 1287 Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870 S+ I+ EDAG+Y A N G+A I + + A Sbjct: 1288 SIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKGEAPTFA 1329 Score = 44.8 bits (101), Expect = 0.002 Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 9/135 (6%) Query: 3554 SGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG 3613 SG P+ + + ++E C + + ++WF +G+P+ + R+K Sbjct: 1611 SGEGPKLASELQPMQVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYGK 1669 Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ 3673 IL + GV DAG Y + TN+ G S + V+ R ++P++ + + I+ Sbjct: 1670 TCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN---VKPEIVGN----VDDIE 1722 Query: 3674 KLEETLHKREEITIE 3688 + ET R +ITI+ Sbjct: 1723 AV-ETEQARFDITIK 1736 Score = 44.8 bits (101), Expect = 0.002 Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 1/98 (1%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P+ ++ +VTEG L +T + ++W+ +G PV+ HR K +Y Sbjct: 1613 EGPKLASELQPMQVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYGKTC 1671 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 L++ D G Y + TN G +++ + V ++ Sbjct: 1672 ILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN 1709 Score = 44.4 bits (100), Expect = 0.002 Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 4/112 (3%) Query: 1293 DAARRTKQVREDITV-MQAPQFSR-ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350 DA + T +V D+ M P+F R + IE +G +Q G +V W+ +G Sbjct: 1501 DAGKATARVNLDVKEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQ--GKPKPKVTWYKDG 1558 Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 K ++ + + ++ ++ P+D G Y C+ATN+ G + ++V Sbjct: 1559 KVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKV 1610 Score = 44.0 bits (99), Expect = 0.003 Identities = 28/86 (32%), Positives = 36/86 (41%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 PD KIEW +GK R T D +TL L D +D+G Y C NK G+ + Sbjct: 775 PDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVD 834 Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQ 3026 V K E K + +E Q Sbjct: 835 VKVEPKHLKPEAVTPMKNIDAVESGQ 860 Score = 44.0 bits (99), Expect = 0.003 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764 + V E C+V + +PT++ WF +G P + R+ D L I D Sbjct: 1046 VQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDD 1103 Query: 3765 AGEYTCRATNKWGSATTTAKI 3785 GEY + TN +G+ T+A I Sbjct: 1104 GGEYEVQVTNNFGTVRTSADI 1124 Score = 44.0 bits (99), Expect = 0.003 Identities = 26/108 (24%), Positives = 55/108 (50%), Gaps = 3/108 (2%) Query: 1832 RREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH 1891 R+ D++V+ + P+ ++L P +++EG C + + ++W+ +G+ ++S H Sbjct: 1604 RKFDIKVS-GEGPKLASELQ-PMQVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDH 1660 Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 R + S L++ V D+G+Y + N G SS ++VQ + Sbjct: 1661 RIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRR 1708 Score = 43.6 bits (98), Expect = 0.004 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G P F + + ++E C++ + + + ++WF +G+P+ + R+K D Sbjct: 1323 GEAPTFASKLQPIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1380 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 L G+ D G Y + TN G S + V+ R Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKR 1418 Score = 43.6 bits (98), Expect = 0.004 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 2/113 (1%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E +PEF + I +K+G A LE G +V W KDG+ + + I Sbjct: 1513 VKEKMFQPEFDRDEVEPIEVKQGEEA--STSLEIQGKPKPKVTWYKDGKVLRETRNIQLM 1570 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014 ++TI T D G Y C A N G ++ ++ + + +A P Sbjct: 1571 SIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGEGPKLASELQP 1623 Score = 43.6 bits (98), Expect = 0.004 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 2/95 (2%) Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828 +P+F R + E+++G A ++ P +V WYKDG+ + + I + Sbjct: 1519 QPEFDRDEVEPIEVKQGEEASTSLEIQ--GKPKPKVTWYKDGKVLRETRNIQLMSIGNTY 1576 Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863 S+ I+ +D G+Y A NK G + I+V+ Sbjct: 1577 SVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVS 1611 Score = 43.2 bits (97), Expect = 0.005 Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 47/236 (19%) Query: 2229 STRIEVE-EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287 S+ ++V+ EPK P VT ++ V G+ A FE +V +P + E+YH L Sbjct: 830 SSPVDVKVEPKHLKPEAVTPMKNIDAVESGQ-ARFEVEVSGSPEP--KFEWYHGSTKLND 886 Query: 2288 AARFHI--TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQ 2345 + + I D +L I++ D G Y + TS ++ T T K + Sbjct: 887 SDKHKIIKAEDKPLYTLIIENVDTTDGGLYKL--------ITSNLAGTTTNKAEL----- 933 Query: 2346 RPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQ--TAHFDCRLIPV 2403 K++E E A F + + T+P+ ++++GQ TA F + Sbjct: 934 ------KVKEKEVAPEFIQTD------------TKPI----DVEQGQDVTASFKIK---- 967 Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 P +V W ++ K + S RI T + I ED G Y C A+N +G+ Sbjct: 968 SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGK 1023 Score = 43.2 bits (97), Expect = 0.005 Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 7/120 (5%) Query: 1546 TQNEAGLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPV 1604 T ++ G +++V + + VD + + P + ++E E ++A F+ IP+ Sbjct: 1389 TMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMGKVDDIEAVETEQAQFD---IPI 1445 Query: 1605 SDATLKV-EWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 V EWYH + G RF +E+ +L I + + +D GTY C A N G+A Sbjct: 1446 KGYPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKA 1505 Score = 43.2 bits (97), Expect = 0.005 Identities = 55/263 (20%), Positives = 101/263 (38%), Gaps = 15/263 (5%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 QG A +++G P P V+W + L E + T V+++ + P D G Y Sbjct: 1534 QGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTII--RTTPDDVGTY 1591 Query: 145 TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204 C A N+ G + I+ G + + T+G TT+ + Sbjct: 1592 MCEATNKAGTSSRKFDIKVSGEGPKLASELQPMQVTE-GDDCKLSCNVTEG-TTKPIIKW 1649 Query: 205 QKVAYTNGTDHSSTDDFKVDTFEYRL----LREVS-FRESITKRYVGESDVQISTEIDRS 259 K +DH + T L + + + IT ++ V+ S +ID Sbjct: 1650 FKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKF---GTVKSSADIDVQ 1706 Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319 V P +I + + E A+F + + G P+P V W+ R+++ + +I + Sbjct: 1707 RRNVKP-EIVGNVDDIEAVETEQARFDITIKGYPKPVVEWYHGPTRILDGGRFKISESEE 1765 Query: 320 HT--TLRVRNTQKSDSGHYTLLA 340 + +L + + D G Y +A Sbjct: 1766 NDMYSLVISDLAMDDLGTYKCVA 1788 Score = 42.3 bits (95), Expect = 0.009 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 9/111 (8%) Query: 755 KYQHQESIEEQTSQRPQF---IRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGR 811 +Y Q I + Q P F ++P+Q E + FEA LTP S ++E+ KDG+ Sbjct: 633 EYTLQLDIPKDKQQPPTFTSEVKPVQ--ANENEQVSVVFEADLTPDS----KIEFLKDGK 686 Query: 812 PITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 P F+ + L+ + +D+G+Y NK G++ S I + Sbjct: 687 PFKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITI 737 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK--STFDFGL 2699 P T +K+ D + GQ + +VE P K EW+ L + K D L Sbjct: 844 PEAVTPMKNIDAVESGQARF---EVEVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPL 900 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 TL I ++ D G+Y +NL G + A +K++++ Sbjct: 901 YTLIIENVDTTDGGLYKLITSNLAGTTTNKAELKVKEK 938 Score = 42.3 bits (95), Expect = 0.009 Identities = 41/145 (28%), Positives = 56/145 (38%), Gaps = 16/145 (11%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV-EWFHNGKPLLTGSRVKTIN--DFGF 3614 PE D+ E A F+ IP+ V EWFH +L G R K + Sbjct: 1133 PEIVGKVHDIEALETEQARFD---IPIKGYPKPVVEWFHGPTRILDGGRFKLSESEENDM 1189 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL------PSHFKSG 3668 L I + D G Y C A N G+ T L VK + + +P+ P K G Sbjct: 1190 YSLVISDLVMDDLGTYKCVANNDAGKTTARANLDVKEK---MFQPEFDKDEVEPIEVKQG 1246 Query: 3669 TESIQKLEETLHKREEIT-IEDEKP 3692 E+ L + E+T +D KP Sbjct: 1247 EEASTSLVIRGKPKPEVTWFKDGKP 1271 Score = 42.3 bits (95), Expect = 0.009 Identities = 21/76 (27%), Positives = 33/76 (43%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 P ++ WF + KPL + S+ I T ED+G Y C+ATN G A+ + Sbjct: 1259 PKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFD 1318 Query: 2863 LRCTGDKNIYFDTQHP 2878 + G+ + P Sbjct: 1319 IGIKGEAPTFASKLQP 1334 Score = 42.3 bits (95), Expect = 0.009 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P F ++ + I+ V E CK+ + + +K WFK+G+PV R +P +D Sbjct: 1326 PTFASKLQPIQ-VTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCT 1382 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531 L + +D G Y N GT S Sbjct: 1383 LTFKGITMDDGGEYEVEVTNNFGTVRTS 1410 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 3/115 (2%) Query: 1826 DSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884 D+ + R +++V P F P ++ +G+ A I+ P P +V WY +G Sbjct: 1501 DAGKATARVNLDVKEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQGKPKP--KVTWYKDG 1558 Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 KVL+ + + ++ I+ +D G Y C+A N G + + V + Sbjct: 1559 KVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGE 1613 Score = 42.3 bits (95), Expect = 0.009 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 2/91 (2%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P+ E++ + V EG C V G I WF +G P + R+ Sbjct: 1615 PKLASELQP-MQVTEGDDCKLSCNVTE-GTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCI 1672 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 L++D + DAG+Y TNK+G+ ++A I Sbjct: 1673 LNLDGVTMADAGDYEVEITNKFGTVKSSADI 1703 Score = 41.9 bits (94), Expect = 0.012 Identities = 43/161 (26%), Positives = 70/161 (43%), Gaps = 9/161 (5%) Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193 +SV L K + P FT+ +Q K G+ VV D KI+ Y +G+ + Sbjct: 2 VSVSLIIAPAIK-KAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFK 58 Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253 + R+ D ++L DSG Y C NKYG+ ++ATI + + E + Sbjct: 59 SNYRL----DGENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATI--FIEEEKKKEMIV 112 Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKL 3294 D+ K EL GA ++ T + + + + +VT L Sbjct: 113 TDTTFKPIELSLPFGAPDESVQTVAVDVKQIEKKPVEVTML 153 Score = 41.9 bits (94), Expect = 0.012 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 5/106 (4%) Query: 3412 VEEEKGKAPVFTVPLSNIE-NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470 + ++K + P FT + ++ N E + FEA LTP K+E+ +GK K Sbjct: 640 IPKDKQQPPTFTSEVKPVQANENEQVSVVFEADLTPDS----KIEFLKDGKPFKGDENSD 695 Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516 D ++L +DSG Y C N +G++ + + ++ K+ Sbjct: 696 YSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKK 741 Score = 41.9 bits (94), Expect = 0.012 Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 8/137 (5%) Query: 1826 DSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884 D+ + R +++V P F P ++ +G+ A I P P V W+ +G Sbjct: 1212 DAGKTTARANLDVKEKMFQPEFDKDEVEPIEVKQGEEASTSLVIRGKPKPE--VTWFKDG 1269 Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944 K L+ + + ++ I+ ED+G Y C+A N G+A + + ++ + Sbjct: 1270 KPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKGEAPTF- 1328 Query: 1945 DSQHESALEKIQYLEDD 1961 S L+ IQ E+D Sbjct: 1329 ----ASKLQPIQVTEED 1341 Score = 41.9 bits (94), Expect = 0.012 Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 15/128 (11%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV-EWFHNGKPLLTGSRVKTIN--DFGF 3614 PE D+ E A F+ IP+ V EW+H +L G R K + Sbjct: 1422 PEIMGKVDDIEAVETEQAQFD---IPIKGYPKPVVEWYHGPTRILDGGRFKISESEENDM 1478 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL------PSHFKSG 3668 L I + D G Y C A+N G+AT L VK + + +P+ P K G Sbjct: 1479 YSLVISNLIMDDLGTYKCVASNDAGKATARVNLDVKEK---MFQPEFDRDEVEPIEVKQG 1535 Query: 3669 TESIQKLE 3676 E+ LE Sbjct: 1536 EEASTSLE 1543 Score = 41.9 bits (94), Expect = 0.012 Identities = 30/155 (19%), Positives = 65/155 (41%), Gaps = 8/155 (5%) Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764 +V + P ++ ++V E + G K ++W ++G P+++ +R+ + Sbjct: 1609 KVSGEGPKLASELQPMQVTEGDDCKLSCN-VTEGTTKPIIKWFKDGEPVKSDHRIKPSYY 1667 Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824 LN+ V D+G Y N+ G +S+ + VQ + + + + + Sbjct: 1668 GKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRR------NVKPEIVGNVDDI 1721 Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859 E Q R D+ + P + +GPT++ +G Sbjct: 1722 EAVETEQARFDITIKGYPKP-VVEWYHGPTRILDG 1755 Score = 41.9 bits (94), Expect = 0.012 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 6/131 (4%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 PK ++++ V E + + C V + K I+W+++G+ + S HR + Y L Sbjct: 1615 PKLASELQPMQVTEGDDCKLSCNVT-EGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCIL 1673 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPRGMKRSEALTQM 3946 ++ V D+G+Y N FG + A I ++ P+I+ ++ +A + Sbjct: 1674 NLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRNVKPEIVGNVDDIEAVETEQA--RF 1731 Query: 3947 EATIKKYTSEV 3957 + TIK Y V Sbjct: 1732 DITIKGYPKPV 1742 Score = 41.9 bits (94), Expect = 0.012 Identities = 19/59 (32%), Positives = 30/59 (50%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 ++W KDG PV++ RI + L + VT+ DAG Y N G +SA++ + Sbjct: 1647 IKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDV 1705 Score = 41.5 bits (93), Expect = 0.016 Identities = 35/157 (22%), Positives = 63/157 (40%), Gaps = 13/157 (8%) Query: 1839 AVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND 1898 A+ +AP F + L K G+ ++ D +++ Y +GK+ +S +R N Sbjct: 11 AIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRLDGEN- 67 Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ---SKESIIRDSQHESALEKI 1955 L +DSG Y C N G++ S + ++ KE I+ D+ + + Sbjct: 68 ---IMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEKKKEMIVTDTTFKPIELSL 124 Query: 1956 QYLEDDSRYKRAVQDDSFVVEKP----QFGKPIKNAE 1988 + D + D + +KP GK +K E Sbjct: 125 PFGAPDESVQTVAVDVKQIEKKPVEVTMLGKEMKPVE 161 Score = 41.5 bits (93), Expect = 0.016 Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 5/111 (4%) Query: 2228 HSTRIEVEEPKISPPRFVTELRGT-THVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ 2286 ++ ++++ + K PP F +E++ + E + FE + P + +IEF +GK + Sbjct: 634 YTLQLDIPKDKQQPPTFTSEVKPVQANENEQVSVVFEADLTP----DSKIEFLKDGKPFK 689 Query: 2287 SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 +FD + L ++ +D+G Y N G +S + +T+ K Sbjct: 690 GDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPK 740 Score = 41.5 bits (93), Expect = 0.016 Identities = 29/119 (24%), Positives = 57/119 (47%), Gaps = 9/119 (7%) Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301 P F ++L+ V E C+V + +P I+++ +G+ ++S R T+D + Sbjct: 1326 PTFASKLQ-PIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCT 1382 Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360 L + +D GEY V+ N G ++ +A + S +PE + K+ ++E+ E Sbjct: 1383 LTFKGITMDDGGEYEVEVTNNFG------TVRTSADVDVQKRSVKPEIMGKVDDIEAVE 1435 Score = 41.5 bits (93), Expect = 0.016 Identities = 31/135 (22%), Positives = 60/135 (44%), Gaps = 9/135 (6%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P+ +++Q + E + K C + G ++WF +G+P+ +R P Y Sbjct: 1615 PKLASELQPM-QVTEGDDCKLSCNVTE-GTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCI 1672 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA 4092 +N V D+G+Y TN +G ++ A I + ++ ++ IE + +A Sbjct: 1673 LNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN---VKPEIVGNVDDIEAVETEQA 1729 Query: 4093 SWQVT----PEQVVE 4103 + +T P+ VVE Sbjct: 1730 RFDITIKGYPKPVVE 1744 Score = 41.1 bits (92), Expect = 0.021 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 6/99 (6%) Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477 KAP FT L + GE+ ++ T D K++ Y +GK K+ R D Sbjct: 14 KAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL----DGEN 67 Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516 ++L +DSG Y C N YG++ + A++ ++ ++ Sbjct: 68 IMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEK 106 Score = 41.1 bits (92), Expect = 0.021 Identities = 30/129 (23%), Positives = 56/129 (43%), Gaps = 8/129 (6%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 IE ++ K P F+ E+ V E + + + P+ +IE+ +GK R Sbjct: 737 IEPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVT--PDSKIEWLKDGKPFTPDQRS 794 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 TFD ++L ++ +D G Y N G C+S + + V K +PE + Sbjct: 795 DYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK------HLKPEAVT 848 Query: 2352 KIRELESAE 2360 ++ +++ E Sbjct: 849 PMKNIDAVE 857 Score = 41.1 bits (92), Expect = 0.021 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Query: 2775 VFISHLNN-IVCKEGDNIH--FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV 2831 VFI + +V KE + + FE +V P KIEW + KP R T D + Sbjct: 748 VFIHEITKPVVVKEKEQVKLVFEADVTPDS----KIEWLKDGKPFTPDQRSDYTFDGRII 803 Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSATT 2859 +L + T +D+G Y C N G ++ Sbjct: 804 TLMLKDTSVKDTGTYECVIANKYGKCSS 831 Score = 41.1 bits (92), Expect = 0.021 Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G P ++ + ++E C++ + + + ++WF +G+P+ + R+K D Sbjct: 1034 GEAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1091 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 L G+ D G Y + TN G S + V+ R Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRR 1129 Score = 41.1 bits (92), Expect = 0.021 Identities = 37/186 (19%), Positives = 81/186 (43%), Gaps = 10/186 (5%) Query: 2074 GLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRV 2133 G+ +D E ++ ++ ++ +P + + +E + E ++A F+ + Sbjct: 1387 GITMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMGKVDDIEAV-ETEQAQFDIPI 1445 Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTH--DFGYVALDILYTYAEDSGTYMCKATNKLG 2191 + P ++W+H +I G R++ + + +L I +D GTY C A+N G Sbjct: 1446 KGYPKP--VVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAG 1503 Query: 2192 EAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE---EPKISPPRFVTEL 2248 +A L V + + +E I + + ST +E++ +PK++ + L Sbjct: 1504 KATARVNLDV--KEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVL 1561 Query: 2249 RGTTHV 2254 R T ++ Sbjct: 1562 RETRNI 1567 Score = 41.1 bits (92), Expect = 0.021 Identities = 21/79 (26%), Positives = 36/79 (45%) Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900 +E +G +E + PK ++ WY++GK+L + + S+ I+ +D G Sbjct: 1530 IEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVG 1589 Query: 3901 EYICRAVNDFGEDFTKATI 3919 Y+C A N G K I Sbjct: 1590 TYMCEATNKAGTSSRKFDI 1608 Score = 41.1 bits (92), Expect = 0.021 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 2/84 (2%) Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491 +++GE A L P KV WY +GK L+ + + I T P+D G Sbjct: 1532 VKQGEEA--STSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVG 1589 Query: 3492 EYLCRAYNNYGEAVTTASMKVQGK 3515 Y+C A N G + +KV G+ Sbjct: 1590 TYMCEATNKAGTSSRKFDIKVSGE 1613 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 6/107 (5%) Query: 666 PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAV 725 P KIEWLK+G+ R F I+L + +++D+G Y C + G + Sbjct: 775 PDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVD 834 Query: 726 LHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQF 772 + V P+ PE + ++ ++ Q + +E S P+F Sbjct: 835 VKVEPK------HLKPEAVTPMKNIDAVESGQARFEVEVSGSPEPKF 875 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 2/89 (2%) Query: 1985 KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYA 2044 K +V +G V A+ + P +V W +G+ + R T L I + Sbjct: 950 KPIDVEQGQDV--TASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTP 1007 Query: 2045 EDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 EDTGTY C ATN +G+ + +V V ++ Sbjct: 1008 EDTGTYTCTATNNIGKCSSDFTVNVKGEA 1036 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 4/97 (4%) Query: 1437 DESVTIKPRFVTRPKSIE--NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494 D +V +K T ++ V E CK+ + + +K WFK+G+PV R + Sbjct: 1027 DFTVNVKGEAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIK 1084 Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531 P +D L + +D G Y + N GT S Sbjct: 1085 PTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTS 1121 Score = 40.7 bits (91), Expect = 0.028 Identities = 39/163 (23%), Positives = 73/163 (44%), Gaps = 12/163 (7%) Query: 1833 REDVEVAV---NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889 R ++AV N P + +++ L E + A ++ I+ YP P VEW+ + Sbjct: 1119 RTSADIAVQRRNVKPEIVGKVHDIEAL-ETEQARFDIPIKGYPKPV--VEWFHGPTRILD 1175 Query: 1890 GHRYRTSN--DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947 G R++ S + +L I + +D G Y C A N+ G+ ++ R N+ KE + + Sbjct: 1176 GGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGK--TTARANLDVKEKMFQPEF 1233 Query: 1948 HESALEKIQYLEDDSRYKRAVQDDSFVVEKPQF--GKPIKNAE 1988 + +E I+ + + V E F GKP++ ++ Sbjct: 1234 DKDEVEPIEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESK 1276 Score = 40.7 bits (91), Expect = 0.028 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 2/69 (2%) Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV-AMNFGWVYPEDSGEYLCRATNLYGMDET 4059 G P KV W+ +GK +L + R + G ++ P+D G Y+C ATN G Sbjct: 1546 GKPKPKVTWYKDGK-VLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSR 1604 Query: 4060 KAVIKTTGK 4068 K IK +G+ Sbjct: 1605 KFDIKVSGE 1613 Score = 40.3 bits (90), Expect = 0.037 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 7/97 (7%) Query: 3824 PIVSTPPKFITQIKSHTVEE-SEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882 P + P F + ++ + E V +V D K+ I Y++GK+ S +R Sbjct: 10 PAIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSKIDI--YKDGKIFKSNYRL---- 63 Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 D + L A+DSG Y C N +G+ +KATI Sbjct: 64 DGENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATI 100 Score = 40.3 bits (90), Expect = 0.037 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F+ T ++++G +++ P +T W +G+ + + R T Sbjct: 942 PEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVT--WLKDGKTLSSSKRIVPTVRGDTYE 999 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203 L I + ED+GTY C ATN +G+ + T+ V G Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKG 1034 Score = 40.3 bits (90), Expect = 0.037 Identities = 22/75 (29%), Positives = 35/75 (46%) Query: 2385 IDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDE 2444 ++ I+ Q L+ G P +V WF++ K + +S I + S+ I E Sbjct: 1238 VEPIEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPE 1297 Query: 2445 DEGVYMCRASNLLGE 2459 D G YMC A+N G+ Sbjct: 1298 DAGTYMCEATNPSGK 1312 Score = 40.3 bits (90), Expect = 0.037 Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%) Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491 +++GE A L P +V W+ +GK L+ + + I T PED+G Sbjct: 1243 VKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAG 1300 Query: 3492 EYLCRAYNNYGEAVTTASMKVQGK 3515 Y+C A N G+A + ++G+ Sbjct: 1301 TYMCEATNPSGKASKNFDIGIKGE 1324 Score = 40.3 bits (90), Expect = 0.037 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 5/103 (4%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRV-EPINDPHLTIDWFHNGQKIRAGHRYRTTHDF 2164 G+ P + L ++ + EGD C V E P I WF +G+ +++ HR + ++ Sbjct: 1612 GEGPKLASELQPMQ-VTEGDDCKLSCNVTEGTTKP--IIKWFKDGEPVKSDHRIKPSYYG 1668 Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207 L++ D+G Y + TNK G ++ + V RN+ Sbjct: 1669 KTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQ-RRNV 1710 Score = 40.3 bits (90), Expect = 0.037 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712 ++ EG L V T + I+WFK+G + + R+K ++ L+++ + D+ Sbjct: 1625 QVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADA 1683 Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRH 2738 G Y + TN G S+A I ++ R+ Sbjct: 1684 GDYEVEITNKFGTVKSSADIDVQRRN 1709 Score = 40.3 bits (90), Expect = 0.037 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Query: 1465 ECKLE-PVTDSNLK--VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521 +CKL VT+ K ++WFK+G+PV HR +P + L++ + D+G Y Sbjct: 1631 DCKLSCNVTEGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEI 1690 Query: 1522 VNLVGT 1527 N GT Sbjct: 1691 TNKFGT 1696 Score = 39.9 bits (89), Expect = 0.049 Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 6/91 (6%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P F + +Q K G+ ++V D K++ + +GK +R D ++ Sbjct: 16 PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL----DGENIM 69 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372 L ++SG YEC+ TNK G+ S+KA + Sbjct: 70 LTFKNASAKDSGTYECMVTNKYGKSSSKATI 100 Score = 39.9 bits (89), Expect = 0.049 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 2/98 (2%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 QAP FI ++ P + E + + PD ++EW +GK R + D Sbjct: 745 QAPVFIHEITKPVVVKEKEQVKLVFEADVTPDS--KIEWLKDGKPFTPDQRSDYTFDGRI 802 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 L + +D+G Y C N G+ S + + V+ K Sbjct: 803 ITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK 840 Score = 39.9 bits (89), Expect = 0.049 Identities = 28/134 (20%), Positives = 54/134 (40%), Gaps = 8/134 (5%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F L+ + E + ++ + +PT+K W K+G+ +++ R + +L Sbjct: 1326 PTFASKLQPIQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTL 1383 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756 + + D GEY + G T A + V ++ S PE + + +E Sbjct: 1384 TFKGITMDDGGEYEVEVTNNFGTVRTSADVDV------QKRSVKPEIMGKVDDIEAVETE 1437 Query: 757 QHQESIEEQTSQRP 770 Q Q I + +P Sbjct: 1438 QAQFDIPIKGYPKP 1451 Score = 39.9 bits (89), Expect = 0.049 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 1/88 (1%) Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994 +E + P K+ WY +GKVL + +L S ++ ++ D G Y C+A NK G Sbjct: 1542 LEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGT 1601 Query: 2995 AFTSSTVYCTSK-DNLIERTQHPKGTEG 3021 + + + + L Q + TEG Sbjct: 1602 SSRKFDIKVSGEGPKLASELQPMQVTEG 1629 Score = 39.5 bits (88), Expect = 0.065 Identities = 23/105 (21%), Positives = 53/105 (50%), Gaps = 7/105 (6%) Query: 1707 ITQAPVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765 I +AP FT ++ ++ + +++ D K+ + ++G +++ RL D Sbjct: 12 IKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSKIDI--YKDGKIFKSNYRL----DG 65 Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810 + L K + +DSGTY C N+ G++ + +T+F++ + ++ Sbjct: 66 ENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEKKKEM 110 Score = 39.5 bits (88), Expect = 0.065 Identities = 55/218 (25%), Positives = 86/218 (39%), Gaps = 38/218 (17%) Query: 1444 PRFVTRPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502 P F + K ++ N E V FE L P DS K+E+ K+G+P D + Sbjct: 648 PTFTSEVKPVQANENEQVSVVFEADLTP--DS--KIEFLKDGKPFKGDENSDYSFDGRNI 703 Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562 L + +DSG Y C N G +S++D+ +I + + Sbjct: 704 LLSFKNATQKDSGTYECVLTNKHG----------QSSSDV-----------KITIEPKKE 742 Query: 1563 KYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKS 1622 K + E+T P+ V+ KE + FE + P S K+EW + KP Sbjct: 743 KKQAPVFIHEITK--PVV------VKEKEQVKLVFEADVTPDS----KIEWLKDGKPFTP 790 Query: 1623 GSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 R T + + L + +D+GTY C N G+ Sbjct: 791 DQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGK 828 Score = 39.5 bits (88), Expect = 0.065 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 10/124 (8%) Query: 3547 TLTPEAESGNPPEFT---TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTG 3603 T+ P+ E P F T P + E FE + P DS ++EW +GKP Sbjct: 736 TIEPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTP--DS--KIEWLKDGKPFTPD 791 Query: 3604 SRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663 R D + L + +D G Y C N++G+ + ++V+ + L+P+ + Sbjct: 792 QRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPKH---LKPEAVT 848 Query: 3664 HFKS 3667 K+ Sbjct: 849 PMKN 852 Score = 39.5 bits (88), Expect = 0.065 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 3/97 (3%) Query: 637 PQFI-VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 P+FI K + +G + +I+ P ++ WLK+G+++ +S R R Sbjct: 942 PEFIQTDTKPIDVEQGQDVTASFKIK--SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYE 999 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732 L + +D+G YTC A + G + ++V A Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEA 1036 Score = 39.5 bits (88), Expect = 0.065 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 2/91 (2%) Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749 EK P F + + I+V +G + G P + WF +G+P + + Sbjct: 1226 EKMFQPEFDKDEVEPIEVKQGEEASTSLVIR--GKPKPEVTWFKDGKPLRESKNIQQKSI 1283 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780 ++ I DAG Y C ATN G A+ Sbjct: 1284 GDTYSIRIVRTSPEDAGTYMCEATNPSGKAS 1314 Score = 39.5 bits (88), Expect = 0.065 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 2778 SHLNNIVCKEGDNIHFECNV-EPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836 S L + EGD+ CNV E + P +K WF + +P+ S R K ++ L++ Sbjct: 1619 SELQPMQVTEGDDCKLSCNVTEGTTKPIIK--WFKDGEPVKSDHRIKPSYYGKTCILNLD 1676 Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSL 2863 D+G Y + TN G+ +S + Sbjct: 1677 GVTMADAGDYEVEITNKFGTVKSSADI 1703 Score = 39.1 bits (87), Expect = 0.086 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 6/91 (6%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P FT +++ + G V +V D +ID + +G+ F + R+ N I Sbjct: 16 PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRLDGEN----IM 69 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 L A+D+G Y C TNK+G +++ A I Sbjct: 70 LTFKNASAKDSGTYECMVTNKYGKSSSKATI 100 Score = 39.1 bits (87), Expect = 0.086 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 9/134 (6%) Query: 1015 GGLEKIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQ--SAHFEARVEPQS 1071 GGL K+ A + + E +VK + P F+ + +GQ +A F+ + +P+ Sbjct: 913 GGLYKLITSNLAGTTTNKAELKVKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKP 972 Query: 1072 DLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSA 1131 +T W +GK ++S+ RI L I ED+G YT A N G+ S+ Sbjct: 973 QVT----WLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKC--SS 1026 Query: 1132 SMTVETRSSIDTSS 1145 TV + T S Sbjct: 1027 DFTVNVKGEAPTLS 1040 Score = 39.1 bits (87), Expect = 0.086 Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 7/119 (5%) Query: 1546 TQNEAGLEQIQVLEDRSKYHRT-DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPV 1604 T ++ G ++QV + + D+ + P + ++E E ++A F+ IP+ Sbjct: 1100 TMDDGGEYEVQVTNNFGTVRTSADIAVQRRNVKPEIVGKVHDIEALETEQARFD---IPI 1156 Query: 1605 SDATLKV-EWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 V EW+H + G RF +E+ +L I + +D GTY C A N G+ Sbjct: 1157 KGYPKPVVEWFHGPTRILDGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGK 1215 Score = 39.1 bits (87), Expect = 0.086 Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 4/134 (2%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601 IVR++ +AG + K + + + +AP + L+ +++ E ++ Sbjct: 1291 IVRTSPEDAGTYMCEATNPSGKASKNFDIG-IKGEAPTFASKLQPIQVTEEDECKLTCKV 1349 Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 + + T+K W+ + +P+KS R T + L +D G Y N G Sbjct: 1350 SGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTV 1407 Query: 1662 VTSGIAIVHSKKSI 1675 TS V K+S+ Sbjct: 1408 RTSADVDV-QKRSV 1420 Score = 39.1 bits (87), Expect = 0.086 Identities = 30/133 (22%), Positives = 55/133 (41%), Gaps = 4/133 (3%) Query: 1007 IIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEAR 1066 I+ S G + + + SK + +K + P F L+ ++ E + Sbjct: 1291 IVRTSPEDAGTYMCEATNPSGKASKNFDIGIK-GEAPTFASKLQPI-QVTEEDECKLTCK 1348 Query: 1067 VEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGE 1126 V + T++W+ +G+ + S RI+ +D L + +D G Y V N G Sbjct: 1349 VSGLPE--PTIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGT 1406 Query: 1127 AQLSASMTVETRS 1139 + SA + V+ RS Sbjct: 1407 VRTSADVDVQKRS 1419 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/102 (24%), Positives = 53/102 (51%), Gaps = 13/102 (12%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDD-PDLKVEWFYNGKKLPHGHRYRTFHD---- 3336 P+ + ++ D+ + VE + A F+ +P+ P VEW++ ++ G R++ Sbjct: 1422 PEIMGKVDDI-EAVETEQAQFD---IPIKGYPKPVVEWYHGPTRILDGGRFKISESEEND 1477 Query: 3337 -FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377 + +VI +++ ++ G Y+CVA+N G+ + + NL K Sbjct: 1478 MYSLVISNLIM---DDLGTYKCVASNDAGKATARVNLDVKEK 1516 Score = 38.7 bits (86), Expect = 0.11 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 9/98 (9%) Query: 3558 PEFTTT---PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-VKTINDFG 3613 PEF T P D+ ++ +A F+ + P +V W +GK L + R V T+ Sbjct: 942 PEFIQTDTKPIDVEQGQDVTASFKIKSKP----KPQVTWLKDGKTLSSSKRIVPTVRGDT 997 Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651 + ++ I D G YTC ATN G+ + + VKG Sbjct: 998 YELV-IKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKG 1034 Score = 38.7 bits (86), Expect = 0.11 Identities = 18/59 (30%), Positives = 29/59 (49%) Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 ++ + P V D + E E ARF + G+PKP V W I++G R+K++ Sbjct: 1703 IDVQRRNVKPEIVGNVDDIEAVETEQARFDITIKGYPKPVVEWYHGPTRILDGGRFKIS 1761 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 4/94 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694 P+ + P+K++ A+E G+ FE +E G P K EW + S + I Sbjct: 844 PEAVTPMKNIDAVESGQARFE--VEVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLY 901 Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 +L + +++ D G Y + G KA L V Sbjct: 902 TLIIENVDTTDGGLYKLITSNLAGTTTNKAELKV 935 Score = 38.3 bits (85), Expect = 0.15 Identities = 28/123 (22%), Positives = 50/123 (40%), Gaps = 3/123 (2%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601 I +ST + G + K +D V +AP ++ L+ V++ E ++ Sbjct: 1002 IKKSTPEDTGTYTCTATNNIGKCS-SDFTVNVKGEAPTLSSKLQPVQVTEEDDCKLTCKV 1060 Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 + + T+K W+ + +P+KS R T + L +D G Y + N G Sbjct: 1061 SGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTV 1118 Query: 1662 VTS 1664 TS Sbjct: 1119 RTS 1121 Score = 38.3 bits (85), Expect = 0.15 Identities = 29/130 (22%), Positives = 54/130 (41%), Gaps = 5/130 (3%) Query: 2074 GLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRV 2133 G+ +D E ++ I ++ +P + + +E L E ++A F+ + Sbjct: 1098 GITMDDGGEYEVQVTNNFGTVRTSADIAVQRRNVKPEIVGKVHDIEAL-ETEQARFDIPI 1156 Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTH--DFGYVALDILYTYAEDSGTYMCKATNKLG 2191 + P ++WFH +I G R++ + + +L I +D GTY C A N G Sbjct: 1157 KGYPKP--VVEWFHGPTRILDGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAG 1214 Query: 2192 EAVNTCTLKV 2201 + L V Sbjct: 1215 KTTARANLDV 1224 Score = 38.3 bits (85), Expect = 0.15 Identities = 28/121 (23%), Positives = 50/121 (41%), Gaps = 3/121 (2%) Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749 EK P F + + I+V +G ++ G P ++ W+ +G+ + ++ Sbjct: 1515 EKMFQPEFDRDEVEPIEVKQGEEASTSLEIQ--GKPKPKVTWYKDGKVLRETRNIQLMSI 1572 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK-RDIVLESQLPQGMSGEKI 3808 ++ I D G Y C ATNK G+++ I S + + E Q Q G+ Sbjct: 1573 GNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGEGPKLASELQPMQVTEGDDC 1632 Query: 3809 K 3809 K Sbjct: 1633 K 1633 Score = 38.3 bits (85), Expect = 0.15 Identities = 22/82 (26%), Positives = 35/82 (42%) Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725 +E + P K+ W+K+G L ++ +++I DD G Y C+ATN G Sbjct: 1542 LEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGT 1601 Query: 2726 AVSTASIKIEDRHWLLGESLHP 2747 + IK+ L L P Sbjct: 1602 SSRKFDIKVSGEGPKLASELQP 1623 Score = 37.9 bits (84), Expect = 0.20 Identities = 24/103 (23%), Positives = 50/103 (48%), Gaps = 6/103 (5%) Query: 903 PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962 P + P F + ++ Q+ K G ++ DS +++ KDG+ +++ R+ Sbjct: 10 PAIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL---- 63 Query: 963 NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005 + + LT K+ + D+G Y C N G++++ A + I +K Sbjct: 64 DGENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEK 106 Score = 37.9 bits (84), Expect = 0.20 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 7/99 (7%) Query: 1576 QAPICTTSLKN-VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGF 1634 +AP T+ L+ V+ K G+ +++ SD+ K++ Y + K KS R N Sbjct: 14 KAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRLDGEN---- 67 Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673 + L + +DSGTY C N G++ + + +K Sbjct: 68 IMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEK 106 Score = 37.9 bits (84), Expect = 0.20 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 6/100 (6%) Query: 1576 QAPICTTSLKNVEIKEGQRAH--FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFG 1633 Q P T+ +K V+ E ++ FE L P S K+E+ + KP K + + Sbjct: 646 QPPTFTSEVKPVQANENEQVSVVFEADLTPDS----KIEFLKDGKPFKGDENSDYSFDGR 701 Query: 1634 FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673 + L + +DSGTY C N G++ + + KK Sbjct: 702 NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKK 741 Score = 37.9 bits (84), Expect = 0.20 Identities = 47/196 (23%), Positives = 74/196 (37%), Gaps = 11/196 (5%) Query: 1142 DTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRL 1201 DTS G YE + K P+ E KP V P+ N V G+ + Sbjct: 809 DTSVKDTGTYECVIANKYGKCSSPVDVKVEPKHLKPEAVTPMKNIDAVESGQ---ARFEV 865 Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTY--YDFGFVALDIIHATSADTGEYTVRAVNHLG 1259 E G P + EW+H + + K D L I + + D G Y + N G Sbjct: 866 EVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAG 925 Query: 1260 SAHTSAIVRVIER----SDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT-VMQAPQFS 1314 + A ++V E+ I TDT+ +EQ Q + + + + + +T + S Sbjct: 926 TTTNKAELKVKEKEVAPEFIQTDTKPID-VEQGQDVTASFKIKSKPKPQVTWLKDGKTLS 984 Query: 1315 RALHNIETVEGTNVHL 1330 + + TV G L Sbjct: 985 SSKRIVPTVRGDTYEL 1000 Score = 37.9 bits (84), Expect = 0.20 Identities = 20/66 (30%), Positives = 31/66 (46%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 P ++ W + K L S R T L I + ED+G YTC ATN+ G ++ + Sbjct: 970 PKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKCSSDFT 1029 Query: 2863 LRCTGD 2868 + G+ Sbjct: 1030 VNVKGE 1035 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/107 (23%), Positives = 51/107 (47%), Gaps = 8/107 (7%) Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313 V E C+V + +P I+++ +G+ ++S R T+D +L + +D G Sbjct: 1048 VTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGG 1105 Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360 EY V+ N G ++ + V + + +PE + K+ ++E+ E Sbjct: 1106 EYEVQVTNNFGTVRTSADIAVQRR------NVKPEIVGKVHDIEALE 1146 Score = 37.9 bits (84), Expect = 0.20 Identities = 18/64 (28%), Positives = 32/64 (50%) Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 T++W+ +G+ + S RI+ +D L + +D G Y V N G + SA + V Sbjct: 1067 TIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAV 1126 Query: 1136 ETRS 1139 + R+ Sbjct: 1127 QRRN 1130 Score = 37.9 bits (84), Expect = 0.20 Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 7/113 (6%) Query: 1298 TKQVREDITVMQA---PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354 T + DI V + P+ +H+IE +E + ++ G VEWF I Sbjct: 1117 TVRTSADIAVQRRNVKPEIVGKVHDIEALETEQARFDIPIK--GYPKPVVEWFHGPTRIL 1174 Query: 1355 TGHRFR--PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 G RF+ + E D +L + + +D G Y C A N G+ L V K Sbjct: 1175 DGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGKTTARANLDVKEK 1227 Score = 37.9 bits (84), Expect = 0.20 Identities = 54/219 (24%), Positives = 90/219 (41%), Gaps = 42/219 (19%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPV-GDPTLKVEWFRNEKLIEDSSR--ITKTHDF 2431 +P + +I+ ++ Q A FD IP+ G P VEWF I D R ++++ + Sbjct: 1132 KPEIVGKVHDIEALETEQ-ARFD---IPIKGYPKPVVEWFHGPTRILDGGRFKLSESEEN 1187 Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLE 2491 S+ IS + +D G Y C A+N G+ L+ + +K+ Sbjct: 1188 DMYSLVISDLVMDDLGTYKCVANNDAGKTTARA----------NLDVK--------EKMF 1229 Query: 2492 QPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVEL 2551 QP E D++ +PI E+ +G+ A +V G P W+ +G L Sbjct: 1230 QP------EFDKDEVEPI---------EVKQGEEA--STSLVIRGKPKPEVTWFKDGKPL 1272 Query: 2552 KMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 + + ++ I DAG YMC+A N +G Sbjct: 1273 RESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSG 1311 Score = 37.9 bits (84), Expect = 0.20 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 2672 PNLKIEWFKNGVTLTTGARLK--STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729 P +EWF + G R K + + + +L I+ L DD G Y C A N G+ + Sbjct: 1160 PKPVVEWFHGPTRILDGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGKTTAR 1219 Query: 2730 ASIKIEDR 2737 A++ ++++ Sbjct: 1220 ANLDVKEK 1227 Score = 37.9 bits (84), Expect = 0.20 Identities = 19/55 (34%), Positives = 25/55 (45%) Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055 G P +V WF +GKPL ++ PED+G Y+C ATN G Sbjct: 1257 GKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSG 1311 Score = 37.9 bits (84), Expect = 0.20 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 6/113 (5%) Query: 1719 DIRVAENQAAHFEARLIPV-GDPKLRVEWLRNGVPIEASNR--LTTMHDFGYVALNMKYV 1775 DI E + A F+ IP+ G PK VEW I R ++ + +L + + Sbjct: 1430 DIEAVETEQAQFD---IPIKGYPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNL 1486 Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828 +D GTY C A N+ G+A L V+ K + E +++Q E++S Sbjct: 1487 IMDDLGTYKCVASNDAGKATARVNLDVKEKMFQPEFDRDEVEPIEVKQGEEAS 1539 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/116 (21%), Positives = 51/116 (43%), Gaps = 3/116 (2%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 ++V+E K+ P F + V +G+ A +++ P ++ +Y +GK L+ Sbjct: 1511 LDVKE-KMFQPEFDRDEVEPIEVKQGEEASTSLEIQG--KPKPKVTWYKDGKVLRETRNI 1567 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347 + S+ I P+D G Y +A N G + + V+ +G ++ +P Sbjct: 1568 QLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGEGPKLASELQP 1623 Score = 37.9 bits (84), Expect = 0.20 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G PK +V W ++G + + + M ++ + P+D GTY C A N+ G TS Sbjct: 1546 GKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAG---TS 1602 Query: 1798 STLF 1801 S F Sbjct: 1603 SRKF 1606 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 3/111 (2%) Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889 Y + D+ Q P F +++ P + +E + + PD ++E+ +GK + Sbjct: 634 YTLQLDIPKDKQQPPTFTSEVK-PVQANENEQVSVVFEADLTPDS--KIEFLKDGKPFKG 690 Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 S D L +DSG Y C N GQ+ S +++ ++ K+ Sbjct: 691 DENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKK 741 Score = 37.5 bits (83), Expect = 0.26 Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 5/111 (4%) Query: 2093 KYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152 K P ++ E +P +T + +++ ++ G +A FE VE P +W+H K+ Sbjct: 828 KCSSPVDVKVEPKHLKPEAVTPMKNIDAVESG-QARFE--VEVSGSPEPKFEWYHGSTKL 884 Query: 2153 RAG--HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 H+ D L I D G Y +N G N LKV Sbjct: 885 NDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAELKV 935 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 3/107 (2%) Query: 3675 LEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734 L T + E+ +++++ P + K IDV +G V +++ P ++ W + Sbjct: 923 LAGTTTNKAELKVKEKEVAPEFIQTDTKP-IDVEQGQDVTASFKIK--SKPKPQVTWLKD 979 Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781 G+ ++ R+ L I D G YTC ATN G ++ Sbjct: 980 GKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKCSS 1026 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Query: 1432 KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH 1491 K ++ + + P F+ +V +GQ V K++ + +V W K+G+ ++ Sbjct: 930 KAELKVKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIK--SKPKPQVTWLKDGKTLSSSK 987 Query: 1492 RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 R P L I ED+G YTC A N +G Sbjct: 988 RIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIG 1022 Score = 37.5 bits (83), Expect = 0.26 Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Query: 2672 PNLKIEWFKNGVTLTTGARLK--STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729 P +EW+ + G R K + + + +L I++L DD G Y C A+N G+A + Sbjct: 1449 PKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKATAR 1508 Query: 2730 ASIKIEDR 2737 ++ ++++ Sbjct: 1509 VNLDVKEK 1516 Score = 37.1 bits (82), Expect = 0.35 Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 7/119 (5%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSLD 2834 + +++I E + F+ ++ P +EWF + G R+K + + SL Sbjct: 1136 VGKVHDIEALETEQARFDIPIKGYPKPV--VEWFHGPTRILDGGRFKLSESEENDMYSLV 1193 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893 I+ +D G Y C A N G T +L K F + + + V+Q EEA Sbjct: 1194 ISDLVMDDLGTYKCVANNDAGKTTARANLDV---KEKMFQPEFDKDEVEPIEVKQGEEA 1249 Score = 37.1 bits (82), Expect = 0.35 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 6/91 (6%) Query: 3837 KSHTVE--ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR--TVYDMGFVSLDIL 3892 K H +E E+E RF+ + K PK +EW+ + G R++ + SL I Sbjct: 1138 KVHDIEALETEQARFDIPI--KGYPKPVVEWFHGPTRILDGGRFKLSESEENDMYSLVIS 1195 Query: 3893 YVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 + +D G Y C A ND G+ +A + K+ Sbjct: 1196 DLVMDDLGTYKCVANNDAGKTTARANLDVKE 1226 Score = 37.1 bits (82), Expect = 0.35 Identities = 21/79 (26%), Positives = 33/79 (41%) Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728 R P ++ WFK+G L ++ ++ I +D+G Y C+ATN G+A Sbjct: 1256 RGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASK 1315 Query: 2729 TASIKIEDRHWLLGESLHP 2747 I I+ L P Sbjct: 1316 NFDIGIKGEAPTFASKLQP 1334 Score = 37.1 bits (82), Expect = 0.35 Identities = 18/59 (30%), Positives = 29/59 (49%) Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 V+ K P + D + E E A+F + G+PKP V W I++G R+K++ Sbjct: 1413 VDVQKRSVKPEIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEWYHGPTRILDGGRFKIS 1471 Score = 37.1 bits (82), Expect = 0.35 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 2/95 (2%) Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337 S E PK +++Q + ++ EG + + ++WF +G+ + HR + + Sbjct: 1611 SGEGPKLASELQPM-QVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYG 1668 Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 IL++ ++G+YE TNK G + A++ Sbjct: 1669 KTCILNLDGVTMADAGDYEVEITNKFGTVKSSADI 1703 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 6/114 (5%) Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105 + P FT+ + V G+ ++ T D I+ + +GK ++++R+ Sbjct: 14 KAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSK--IDIYKDGKIFKSNYRLDGEN---- 67 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159 ++L DSGTY C TNK+G++ + ++ K + T + IE Sbjct: 68 IMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEKKKEMIVTDTTFKPIE 121 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/102 (25%), Positives = 40/102 (39%), Gaps = 4/102 (3%) Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTK-FECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026 +K+ P F IQ+ T +++E + P +V W +GK L R P Sbjct: 937 EKEVAPEF---IQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTV 993 Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068 + PED+G Y C ATN G + + G+ Sbjct: 994 RGDTYELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGE 1035 Score = 36.7 bits (81), Expect = 0.46 Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 7/116 (6%) Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSLDITH 2837 +++I E + F+ ++ P +EW+ + G R+K + + SL I++ Sbjct: 1428 VDDIEAVETEQAQFDIPIKGYPKPV--VEWYHGPTRILDGGRFKISESEENDMYSLVISN 1485 Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893 +D G Y C A+N G AT +L K F + + + V+Q EEA Sbjct: 1486 LIMDDLGTYKCVASNDAGKATARVNLDV---KEKMFQPEFDRDEVEPIEVKQGEEA 1538 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/90 (25%), Positives = 37/90 (41%), Gaps = 2/90 (2%) Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629 V E Q ++ +E+K+G+ A + KV WY + K L+ Sbjct: 1513 VKEKMFQPEFDRDEVEPIEVKQGEEASTSLEI--QGKPKPKVTWYKDGKVLRETRNIQLM 1570 Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 + ++ I+ P+D GTY C A N G Sbjct: 1571 SIGNTYSVTIIRTTPDDVGTYMCEATNKAG 1600 Score = 36.7 bits (81), Expect = 0.46 Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 I K+G+ ++ P K+ W+ + K L + + S+ I T +D Sbjct: 1530 IEVKQGEEASTSLEIQGKPKP--KVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDD 1587 Query: 2843 SGIYTCKATNSKGSATTSGSLRCTGD 2868 G Y C+ATN G+++ ++ +G+ Sbjct: 1588 VGTYMCEATNKAGTSSRKFDIKVSGE 1613 Score = 36.3 bits (80), Expect = 0.61 Identities = 31/138 (22%), Positives = 54/138 (39%), Gaps = 5/138 (3%) Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL-- 2962 + ++ KPE + P+ + GQ +VE P+ K EWY L + K+ Sbjct: 838 EPKHLKPEAVTPMKNIDAVESGQARF---EVEVSGSPEPKFEWYHGSTKLNDSDKHKIIK 894 Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022 D TL + +V D G+Y N G + + K+ E Q + Sbjct: 895 AEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAELKVKEKEVAPEFIQTDTKPIDV 954 Query: 3023 EKIQNLEDSLRKEPGQQP 3040 E+ Q++ S + + +P Sbjct: 955 EQGQDVTASFKIKSKPKP 972 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 4/97 (4%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYV 1368 P+ + +IE VE + ++ G VEW+ I G RF+ + E D Sbjct: 1422 PEIMGKVDDIEAVETEQAQFDIPIK--GYPKPVVEWYHGPTRILDGGRFKISESEENDMY 1479 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 +L + ++ +D G Y C A+N G+A L V K Sbjct: 1480 SLVISNLIMDDLGTYKCVASNDAGKATARVNLDVKEK 1516 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP F +K V A E ++ E P KIE+LK+G+ + F I Sbjct: 647 PPTFTSEVKPVQANENEQV--SVVFEADLTPDSKIEFLKDGKPFKGDENSDYSFDGRNIL 704 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 L + +DSG Y C + G + + + + P+ Sbjct: 705 LSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPK 740 Score = 35.9 bits (79), Expect = 0.80 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%) Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493 DI + +KP V + IE +E + F+ ++ VEWF + G RF Sbjct: 1123 DIAVQRRNVKPEIVGKVHDIE-ALETEQARFDIPIKGYPKP--VVEWFHGPTRILDGGRF 1179 Query: 1494 R--PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEA 1550 + + +L I DL+ +D G Y C A N G + T R+ D+ + Q E Sbjct: 1180 KLSESEENDMYSLVISDLVMDDLGTYKCVANNDAG------KTTARANLDVKEKMFQPEF 1233 Query: 1551 GLEQIQVLE 1559 ++++ +E Sbjct: 1234 DKDEVEPIE 1242 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371 P KV W+ +GK L + + I+ ++ G Y C ATNK G S K + Sbjct: 1548 PKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFD 1607 Query: 3372 LKCTSKENLILDSQL 3386 +K S E L S+L Sbjct: 1608 IK-VSGEGPKLASEL 1621 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 6/85 (7%) Query: 2373 RQRPVFTQPLQNIDNIQ--EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKT 2428 ++R V + + N+D+I+ E + A FD + G P VEW+ I D R I+++ Sbjct: 1706 QRRNVKPEIVGNVDDIEAVETEQARFDITI--KGYPKPVVEWYHGPTRILDGGRFKISES 1763 Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRA 2453 + S+ IS + +D G Y C A Sbjct: 1764 EENDMYSLVISDLAMDDLGTYKCVA 1788 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 7/94 (7%) Query: 2500 EPDREFEK-PIFTQVLTGPSELWEGQHAH--YEARVVPVGDPSLRFEWYINGVELKMGSR 2556 EP +E ++ P+F +T P + E + +EA V P + EW +G R Sbjct: 738 EPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTP----DSKIEWLKDGKPFTPDQR 793 Query: 2557 FRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 T D +TL + D G Y C N+ G Sbjct: 794 SDYTFDGRIITLMLKDTSVKDTGTYECVIANKYG 827 Score = 35.5 bits (78), Expect = 1.1 Identities = 21/95 (22%), Positives = 39/95 (41%), Gaps = 2/95 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P L+ V E ++ + +PT+K W K+G+ +++ R + +L Sbjct: 1037 PTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTL 1094 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 + + D GEY + + G T A + V R Sbjct: 1095 TFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRR 1129 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339 E P F +++Q + ++ E ++ + +P +K WF +G+ + R + +D Sbjct: 1324 EAPTFASKLQPI-QVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKT 1380 Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 L ++ GEYE TN G T A++ Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFGTVRTSADV 1413 Score = 35.1 bits (77), Expect = 1.4 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 5/91 (5%) Query: 490 APKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548 AP F + + GE V L + V T +I KDG N L DG L Sbjct: 15 APTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSKIDIYKDGKIFKSNYRL----DGENIML 70 Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARLY 579 A A D+ Y+C N G ++++A ++ Sbjct: 71 TFKNASAKDSGTYECMVTNKYGKSSSKATIF 101 Score = 35.1 bits (77), Expect = 1.4 Identities = 18/72 (25%), Positives = 32/72 (44%) Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900 +E +G + + PK + W+++GK L + S+ I+ ED+G Sbjct: 1241 IEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAG 1300 Query: 3901 EYICRAVNDFGE 3912 Y+C A N G+ Sbjct: 1301 TYMCEATNPSGK 1312 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 6/94 (6%) Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029 K+ P F + +Q Q E ++ D K++ + +GK + K+ + D Sbjct: 13 KKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGK--IFKSNYR--LDGE 66 Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063 + + F +DSG Y C TN YG +KA I Sbjct: 67 NIMLTFKNASAKDSGTYECMVTNKYGKSSSKATI 100 Score = 34.7 bits (76), Expect = 1.9 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 9/106 (8%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F + L K G+ +V +D ID + +G+ ++ +R D + Sbjct: 16 PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSK--IDIYKDGKIFKSNYRL----DGENIM 69 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRN---IILDT 2211 L A+DSGTY C TNK G++ + T+ + + I+ DT Sbjct: 70 LTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEKKKEMIVTDT 115 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 3/76 (3%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 PD KIE+ +GK + + D + L + ++DSG Y C NK G+ +SS Sbjct: 675 PDSKIEFLKDGKPFKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQ--SSSD 732 Query: 3001 VYCTSKDNLIERTQHP 3016 V T + E+ Q P Sbjct: 733 VKITIEPKK-EKKQAP 747 Score = 34.7 bits (76), Expect = 1.9 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 3/85 (3%) Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565 E P F L P ++ E +V + +P+++ W+ +G +K R + T+D Sbjct: 1324 EAPTFASKLQ-PIQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKT 1380 Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590 TL + +D G Y + N G Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFG 1405 Score = 34.7 bits (76), Expect = 1.9 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 6/128 (4%) Query: 3391 EGGLEKLQTLEDSMVRRKDTSVEEEKGKA-PVFTVPLSNIENLREGENAHFEARLTPTDD 3449 +GG +++ + R V+ +K P + +IE + E E A F+ + Sbjct: 1392 DGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMGKVDDIEAV-ETEQAQFDIPIKGYPK 1450 Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFC--DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507 P VEWY + G RF+ + L IS +D G Y C A N+ G+A Sbjct: 1451 P--VVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKATAR 1508 Query: 3508 ASMKVQGK 3515 ++ V+ K Sbjct: 1509 VNLDVKEK 1516 Score = 34.3 bits (75), Expect = 2.5 Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 4/61 (6%) Query: 2942 DLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001 D KI+ Y +GK+ + S ++L + + L + +DSG Y C NK G++ + +T+ Sbjct: 45 DSKIDIYKDGKIFK--SNYRLDGEN--IMLTFKNASAKDSGTYECMVTNKYGKSSSKATI 100 Query: 3002 Y 3002 + Sbjct: 101 F 101 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F S + + E + + E P KIE+ + KP + D + L Sbjct: 650 FTSEVKPVQANENEQVSVV--FEADLTPDSKIEFLKDGKPFKGDENSDYSFDGRNILLSF 707 Query: 2836 THTYEEDSGIYTCKATNSKGSATT 2859 + ++DSG Y C TN G +++ Sbjct: 708 KNATQKDSGTYECVLTNKHGQSSS 731 Score = 34.3 bits (75), Expect = 2.5 Identities = 16/63 (25%), Positives = 29/63 (46%) Query: 1343 RVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 ++EW +GKP R ++ + L L +D+G Y C N+ G+ + ++V Sbjct: 778 KIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKV 837 Query: 1403 IAK 1405 K Sbjct: 838 EPK 840 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 4/71 (5%) Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR--TTHDFGFVTLDINSVVANDAG 2579 E A +E V G P +FEWY +L + + D TL I +V D G Sbjct: 857 ESGQARFEVEVS--GSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGG 914 Query: 2580 LYMCKAINRAG 2590 LY N AG Sbjct: 915 LYKLITSNLAG 925 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/105 (21%), Positives = 49/105 (46%), Gaps = 3/105 (2%) Query: 1036 EVKIT-QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT 1094 ++K++ + P+ L+ ++ EG V + ++W+ +G+ + S +RI+ Sbjct: 1607 DIKVSGEGPKLASELQPM-QVTEGDDCKLSCNVT-EGTTKPIIKWFKDGEPVKSDHRIKP 1664 Query: 1095 YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139 + L++ V D+G Y V N G + SA + V+ R+ Sbjct: 1665 SYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN 1709 Score = 33.9 bits (74), Expect = 3.2 Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 13/119 (10%) Query: 4514 PSFTLTAQN-VNVTSGQLVRLDTKV--TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570 P+FT Q V G+ V L KV T ID+Y K+GK + + R DG Sbjct: 16 PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSKIDIY--KDGKIFKSNYRL-----DGENI 68 Query: 4571 LLILE-AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628 +L + A +DSG YEC+ N G++ ++ + + K K T P E+ P Sbjct: 69 MLTFKNASAKDSGTYECMVTNKYGKS--SSKATIFIEEEKKKEMIVTDTTFKPIELSLP 125 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 6/91 (6%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P F LQ + + G + ++ SD +++ YKDG+ ++ R+ + Sbjct: 16 PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRLDG----ENIM 69 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860 L + A+D+G+Y NK G++ S A+I Sbjct: 70 LTFKNASAKDSGTYECMVTNKYGKSSSKATI 100 Score = 33.9 bits (74), Expect = 3.2 Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 5/137 (3%) Query: 1041 QKPRFLGPLKGTNKIVEGQ-SAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099 Q P F +K Q S FEA + P S +E+ +GK D Sbjct: 646 QPPTFTSEVKPVQANENEQVSVVFEADLTPDSK----IEFLKDGKPFKGDENSDYSFDGR 701 Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEE 1159 + L + +DSG Y V N G++ +T+E + + + K ++E Sbjct: 702 NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITKPVVVKE 761 Query: 1160 SKFVEPMYQIEEISKSK 1176 + V+ +++ + SK Sbjct: 762 KEQVKLVFEADVTPDSK 778 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 3/112 (2%) Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235 +P F + P V +G+ LE G P +V W+ +G+ + + Sbjct: 1519 QPEFDRDEVEPIEVKQGEEASTS--LEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTY 1576 Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI-ERSDIVTDTQNEQAIE 1286 ++ II T D G Y A N G++ ++V E + ++ Q Q E Sbjct: 1577 SVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGEGPKLASELQPMQVTE 1628 Score = 33.5 bits (73), Expect = 4.3 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 2/91 (2%) Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970 PE+I + +GQ + +++ K P ++ W +GK L R T Sbjct: 942 PEFIQTDTKPIDVEQGQDVTASFKIKSKPKP--QVTWLKDGKTLSSSKRIVPTVRGDTYE 999 Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001 L + D+G YTC A N G+ + TV Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTV 1030 Score = 33.5 bits (73), Expect = 4.3 Identities = 15/58 (25%), Positives = 28/58 (48%) Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995 + P ++ W+ +GK L + + S ++ +V D+G Y C+A N G+A Sbjct: 1256 RGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKA 1313 Score = 33.5 bits (73), Expect = 4.3 Identities = 17/72 (23%), Positives = 31/72 (43%) Query: 658 TRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSAT 717 T +E G P K+ W K+G+ + + + S+ ++ D G Y C A + Sbjct: 1540 TSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKA 1599 Query: 718 GVAETKAVLHVT 729 G + K + V+ Sbjct: 1600 GTSSRKFDIKVS 1611 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/90 (21%), Positives = 41/90 (45%), Gaps = 6/90 (6%) Query: 2370 PVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH 2429 P ++ P FT LQ + G+ +++ D K++ +++ K+ + + R+ Sbjct: 10 PAIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL---- 63 Query: 2430 DFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 D + +T + +D G Y C +N G+ Sbjct: 64 DGENIMLTFKNASAKDSGTYECMVTNKYGK 93 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/101 (21%), Positives = 49/101 (48%), Gaps = 7/101 (6%) Query: 1307 VMQAPQFSRALHN-IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365 + +AP F+ L ++ G +V L ++ D +++ + +GK K+ +R + Sbjct: 12 IKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL----DG 65 Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406 + + L + +DSG Y C TN+ G++ + + + +K Sbjct: 66 ENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEK 106 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 6/94 (6%) Query: 2368 PEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGD--PTLKVEWFRNEKLIEDSSRI 2425 P+ +Q PVF + ++E + +L+ D P K+EW ++ K R Sbjct: 739 PKKEKKQAPVFIHEITKPVVVKEKEQV----KLVFEADVTPDSKIEWLKDGKPFTPDQRS 794 Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 T D +++ + +D G Y C +N G+ Sbjct: 795 DYTFDGRIITLMLKDTSVKDTGTYECVIANKYGK 828 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 4/79 (5%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFV 1635 P ++ ++E E ++A F+ + VEWYH + G RF +E+ Sbjct: 1712 PEIVGNVDDIEAVETEQARFDITIKGYPKPV--VEWYHGPTRILDGGRFKISESEENDMY 1769 Query: 1636 ALDIMSCLPEDSGTYTCRA 1654 +L I +D GTY C A Sbjct: 1770 SLVISDLAMDDLGTYKCVA 1788 Score = 32.7 bits (71), Expect = 7.5 Identities = 28/132 (21%), Positives = 62/132 (46%), Gaps = 16/132 (12%) Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643 V S +++ + +GK + R+ N ++L +D+G Y C TN++G+++ Sbjct: 41 VTTSDSKIDIYKDGKIFKSNYRLDGEN----IMLTFKNASAKDSGTYECMVTNKYGKSSS 96 Query: 3644 SCKL---QVKGRQGIILEP-----QLPSHFKSGTESIQ----KLEETLHKREEITIEDEK 3691 + + K ++ I+ + +L F + ES+Q +++ K E+T+ ++ Sbjct: 97 KATIFIEEEKKKEMIVTDTTFKPIELSLPFGAPDESVQTVAVDVKQIEKKPVEVTMLGKE 156 Query: 3692 PNPPRFTVEIKD 3703 P F +E +D Sbjct: 157 MKPVEFKMEAQD 168 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 5/98 (5%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGF 3752 P ++ D I+ E FD ++ G P ++WFH G R + + Sbjct: 1133 PEIVGKVHD-IEALETEQARFDIPIK--GYPKPVVEWFHGPTRILDGGRFKLSESEENDM 1189 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 +L I + D G Y C A N G T A + K Sbjct: 1190 YSLVISDLVMDDLGTYKCVANNDAGKTTARANLDVKEK 1227 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/125 (23%), Positives = 50/125 (40%), Gaps = 7/125 (5%) Query: 3530 GTIDKIAALEGYSGTVDTLTPEAESGNPPEFT---TTPSDLILSENSSAHFECRLIPVND 3586 GT +A+ + T E PEF P ++ E +S E + P Sbjct: 1492 GTYKCVASNDAGKATARVNLDVKEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQGKP--- 1548 Query: 3587 SSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646 +V W+ +GK L ++ ++ + I D G Y C+ATN+ G ++ Sbjct: 1549 -KPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFD 1607 Query: 3647 LQVKG 3651 ++V G Sbjct: 1608 IKVSG 1612 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 3/85 (3%) Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565 E P + L P ++ E +V + +P+++ W+ +G +K R + T+D Sbjct: 1035 EAPTLSSKLQ-PVQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKT 1091 Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590 TL + +D G Y + N G Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFG 1116 Score = 32.3 bits (70), Expect = 9.9 Identities = 31/142 (21%), Positives = 58/142 (40%), Gaps = 5/142 (3%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 ++V+E K+ P F + V +G+ A + P + ++ +GK L+ + Sbjct: 1222 LDVKE-KMFQPEFDKDEVEPIEVKQGEEASTSLVIRG--KPKPEVTWFKDGKPLRESKNI 1278 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 S+ I PEDAG Y +A N G + + + KG + + + + ++ Sbjct: 1279 QQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASK--NFDIGIKGEAPTFASKLQPIQ 1336 Query: 2352 KIRELESAEPFKRPEIPEPVTR 2373 E E K +PEP + Sbjct: 1337 VTEEDECKLTCKVSGLPEPTIK 1358 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 1/62 (1%) Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYD 4176 + + V++GE A + G PKP+V W +G + +L G Y I +T D Sbjct: 1528 EPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDD 1587 Query: 4177 TG 4178 G Sbjct: 1588 VG 1589 Score = 32.3 bits (70), Expect = 9.9 Identities = 25/125 (20%), Positives = 52/125 (41%), Gaps = 6/125 (4%) Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601 I+R+T ++ G + R + +V+ + P + L+ +++ EG Sbjct: 1580 IIRTTPDDVGTYMCEATNKAGTSSRKFDI-KVSGEGPKLASELQPMQVTEGDDCKLSCN- 1637 Query: 1602 IPVSDATLK--VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 V++ T K ++W+ + +P+KS R + L++ D+G Y N G Sbjct: 1638 --VTEGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFG 1695 Query: 1660 EAVTS 1664 +S Sbjct: 1696 TVKSS 1700 >SB_26711| Best HMM Match : I-set (HMM E-Value=0) Length = 327 Score = 153 bits (370), Expect = 4e-36 Identities = 96/328 (29%), Positives = 157/328 (47%), Gaps = 21/328 (6%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P+ T K+ E ++A V F G P P ++W+++ +K + T + LII Sbjct: 9 PVITSKLTRVECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLII 68 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 ++ + D + V N G+A +A ++V E R +G G P F ++V V G+ Sbjct: 69 QEAIINDEGSYRCVVRNELGSALSTAEVLVNE-REKGEG----PRFEERLRDVRVEIGR- 122 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED---GTYTLLILEAYPQDSGKYECV 4587 KV + P +V W K + + R I+++D G + L I + P+D G Y+CV Sbjct: 123 -EASFKVRVSLPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCV 181 Query: 4588 AINSAGEARCDAECVVS-----LPATKDKPK--PQT-KAANAPPEIIEPLKDKIVAEGQA 4639 A N GE+ C A ++ P D+ + P++ K PEI++PLK+ V E Sbjct: 182 AFNEVGESSCKANLLLKEEEIVAPQVLDEVEAAPESSKQRGFAPEILQPLKEVNVPENDT 241 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 F C++ P PTV+W + + + + TL I++A D G YKCVA N Sbjct: 242 AIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARN 301 Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPL 4727 + G ++ +AKL+V + D +TPL Sbjct: 302 NFGDISTSAKLRVVVNSKPD---IITPL 326 Score = 125 bits (301), Expect = 1e-27 Identities = 98/325 (30%), Positives = 146/325 (44%), Gaps = 39/325 (12%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 P T V G L + TG+ V W K+G ++P+ R ++ + TL+I Sbjct: 9 PVITSKLTRVECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLII 68 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633 EA D G Y CV N G A AE +V+ ++ K + P E L+D Sbjct: 69 QEAIINDEGSYRCVVRNELGSALSTAEVLVN-----EREKGEG------PRFEERLRDVR 117 Query: 4634 VAEGQAIEFSCKIVGKPLPT-VQWYKGDKLIKPSKYFQM-SRTADE--YTLRISEAFPED 4689 V G+ F ++ LP V W+KG+++I + F + AD+ + L I + PED Sbjct: 118 VEIGREASFKVRV---SLPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPED 174 Query: 4690 EGDYKCVAYNSAGRVTVAAKL-----KVTQPDQADNLPA--------------LTPLRDI 4730 G YKCVA+N G + A L ++ P D + A L PL+++ Sbjct: 175 LGVYKCVAFNEVGESSCKANLLLKEEEIVAPQVLDEVEAAPESSKQRGFAPEILQPLKEV 234 Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790 V E A FK ++T+ PT++WLR+G + E + A L I + D G+ Sbjct: 235 NVPENDTAIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGS 294 Query: 4791 FTCRATTAAGQVETSAKL--VVKSK 4813 + C A G + TSAKL VV SK Sbjct: 295 YKCVARNNFGDISTSAKLRVVVNSK 319 Score = 95.5 bits (227), Expect = 9e-19 Identities = 88/336 (26%), Positives = 142/336 (42%), Gaps = 55/336 (16%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P I K + EG A V+ +G+P P V WFK+G L +N+ T + TL + Sbjct: 9 PVITSKLTRVECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLII 68 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 + +D G Y C+V + + S E V ++ Sbjct: 69 QEAIINDEGSYR--------CVVRNELGSALSTAEVLVNER------------------- 101 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 EK P+F + +D V G+ F RV+ P EV WF + I D I+ +++ Sbjct: 102 -EKGEGPRFEERLRDVRVEIGREASFKVRVS-LP-AEVDWFKGEEMIDDTGRFMIIDDDA 158 Query: 446 --GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV-------------- 489 G L I +V D GV CVA N+ GE++ C+ N++ KE+ + Sbjct: 159 DKGLFQLSIDDVRPEDLGVYKCVAFNEVGESS--CKANLLLKEEEIVAPQVLDEVEAAPE 216 Query: 490 -------APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542 AP+ ++ +NV E + + R +P P + W +DGV + + Sbjct: 217 SSKQRGFAPEILQPLKEVNVPENDTAIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYL 276 Query: 543 GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 +TL I +A+ +D Y+C A+N G +T A+L Sbjct: 277 DEVATLTINQARDTDMGSYKCVARNNFGDISTSAKL 312 Score = 91.5 bits (217), Expect = 2e-17 Identities = 75/312 (24%), Positives = 142/312 (45%), Gaps = 26/312 (8%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 TG + +EWF +G ++ ++R+ L I D G+Y C N+ G A Sbjct: 33 TGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEGSYRCVVRNELGSALS 92 Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194 + ++ ++ KG+ PRF ++++ ++ G+ A F+ V V P +++W+ + + Sbjct: 93 TAEVLVNEREKGEGPRFEERLRDVR-VEIGREASFK---VRVSLP-AEVDWFKGEEMIDD 147 Query: 3195 STRIKTV---SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251 + R + +D G L I + D G Y C A+N+ GE +A + Sbjct: 148 TGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANL-----------L 196 Query: 3252 LQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDD 3311 L+ + + + L+ ++ A + + A P+ + +++V + E +A F+ R+ Sbjct: 197 LKEEEIVAPQVLDEVEAAPESSKQRGFA--PEILQPLKEV-NVPENDTAIFKCRVTA--S 251 Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371 P VEW +G ++ G R + + L I + + G Y+CVA N G ST A Sbjct: 252 PAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAK 311 Query: 3372 LK--CTSKENLI 3381 L+ SK ++I Sbjct: 312 LRVVVNSKPDII 323 Score = 78.6 bits (185), Expect = 1e-13 Identities = 63/230 (27%), Positives = 99/230 (43%), Gaps = 23/230 (10%) Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT---ETNNF 1632 + P L++V ++ G+ A F+ R+ +V+W+ + + RF + + Sbjct: 105 EGPRFEERLRDVRVEIGREASFKVRV----SLPAEVDWFKGEEMIDDTGRFMIIDDDADK 160 Query: 1633 GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLE 1692 G L I PED G Y C A N +GE+ S K+ L + E P++ L+ Sbjct: 161 GLFQLSIDDVRPEDLGVYKCVAFNEVGES---------SCKANLLLKEEEIVAPQV--LD 209 Query: 1693 DTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVP 1752 + S Q AP P+K++ V EN A F+ R+ P VEWLR+GV Sbjct: 210 EVEAAPESSKQRGF---APEILQPLKEVNVPENDTAIFKCRV--TASPAPTVEWLRDGVR 264 Query: 1753 IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 + R+ + L + D G+Y C A N G+ TS+ L V Sbjct: 265 VTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRV 314 Score = 76.2 bits (179), Expect = 6e-13 Identities = 67/242 (27%), Positives = 110/242 (45%), Gaps = 25/242 (10%) Query: 904 ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR---ITT 960 E + P F+ ++D + ++ G A F+ R+ + V+W K ++ + R I Sbjct: 102 EKGEGPRFEERLRD-VRVEIGREASFKVRVSLPAE----VDWFKGEEMIDDTGRFMIIDD 156 Query: 961 FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020 + G L+I V D G Y C A+N +G+++ ANL ++ +++I+A P L+++ Sbjct: 157 DADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANL-LLKEEEIVA----PQVLDEV 211 Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080 + ++S+ P L PLK N + E +A F+ RV TVEW Sbjct: 212 EAAPESSKQRGFA---------PEILQPLKEVN-VPENDTAIFKCRVTASP--APTVEWL 259 Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140 +G ++T RI + L I R D G Y VARN G+ SA + V S Sbjct: 260 RDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSK 319 Query: 1141 ID 1142 D Sbjct: 320 PD 321 Score = 75.4 bits (177), Expect = 1e-12 Identities = 68/241 (28%), Positives = 105/241 (43%), Gaps = 28/241 (11%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARL-IPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765 + P F ++D+RV + A F+ R+ +P V+W + I+ + R + D Sbjct: 105 EGPRFEERLRDVRVEIGREASFKVRVSLPA-----EVDWFKGEEMIDDTGRFMIIDDDAD 159 Query: 1766 -GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824 G L++ V PED G Y C A NE+GE+ KA+L L+ + A Q + ++ Sbjct: 160 KGLFQLSIDDVRPEDLGVYKCVAFNEVGES--------SCKANLLLKEEEIVAPQVLDEV 211 Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884 E + ++ AP + L + E +A ++CR+ P P VEW +G Sbjct: 212 EAAPESSKQRGF------APEILQPLK-EVNVPENDTAIFKCRVTASPAPT--VEWLRDG 262 Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS--IRLNVQSKESI 1942 + G R A L I D G Y C A NN G +S +R+ V SK I Sbjct: 263 VRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSKPDI 322 Query: 1943 I 1943 I Sbjct: 323 I 323 Score = 73.3 bits (172), Expect = 4e-12 Identities = 70/252 (27%), Positives = 116/252 (46%), Gaps = 31/252 (12%) Query: 3265 SLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARL-VPVDDPDLKVEWFYNGK 3323 +L A+ E P+F +++DV ++ G+ A F+ R+ +P + V+WF + Sbjct: 90 ALSTAEVLVNEREKGEGPRFEERLRDV-RVEIGREASFKVRVSLPAE-----VDWFKGEE 143 Query: 3324 KLPHGHRYRTFHDF---GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380 + R+ D G+ L I E+ G Y+CVA N++G S KANL KE Sbjct: 144 MIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLL--KEEE 201 Query: 3381 ILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHF 3440 I+ Q+ L++++ +S +++G AP PL + N+ E + A F Sbjct: 202 IVAPQV-------LDEVEAAPES---------SKQRGFAPEILQPLKEV-NVPENDTAIF 244 Query: 3441 EARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNN 3500 + R+T + P VEW +G + G R L I+ D G Y C A NN Sbjct: 245 KCRVTASPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNN 302 Query: 3501 YGEAVTTASMKV 3512 +G+ T+A ++V Sbjct: 303 FGDISTSAKLRV 314 Score = 71.3 bits (167), Expect = 2e-11 Identities = 82/298 (27%), Positives = 119/298 (39%), Gaps = 34/298 (11%) Query: 988 NAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLG 1047 N + T ++ T++ ++ II + + + + S E K + PRF Sbjct: 53 NRVSAETDESSCTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNEREK-GEGPRFEE 111 Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR---IQTYHDFGYVALD 1104 L+ ++ G+ A F+ RV L V+W+ + I R I D G L Sbjct: 112 RLRDV-RVEIGREASFKVRVS----LPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQLS 166 Query: 1105 IASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVE 1164 I VR ED GVY VA N GE+ A++ + K I + ++ Sbjct: 167 IDDVRPEDLGVYKCVAFNEVGESSCKANLLL-----------------KEEEIVAPQVLD 209 Query: 1165 PMYQIEEISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221 + E SK + P +QPL V E +CR+ PT VEW +G VT Sbjct: 210 EVEAAPESSKQRGFAPEILQPLKEVN-VPENDTAIFKCRVTASPAPT--VEWLRDGVRVT 266 Query: 1222 VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS--DIVT 1277 G R Y L I A D G Y A N+ G TSA +RV+ S DI+T Sbjct: 267 EGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSKPDIIT 324 Score = 70.9 bits (166), Expect = 2e-11 Identities = 70/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%) Query: 3674 KLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH 3733 +L L E + E EK PRF ++D + V G F RV + +DWF Sbjct: 86 ELGSALSTAEVLVNEREKGEGPRFEERLRD-VRVEIGREASFKVRVSLPAE----VDWFK 140 Query: 3734 NGRPFATGSRVHTLNDF---GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 R ++D G L ID + D G Y C A N+ G + S K Sbjct: 141 GEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGES--------SCK 192 Query: 3791 RDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850 +++L+ + + ++ + + E+E AP+ P+ + +K V E++ F+ Sbjct: 193 ANLLLKEE--EIVAPQVLDEVEA-----APESSKQRGFAPEILQPLKEVNVPENDTAIFK 245 Query: 3851 CRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910 CRV P +EW R+G + G R Y +L I D G Y C A N+F Sbjct: 246 CRVTASPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNF 303 Query: 3911 GEDFT--KATISCKKLPDII 3928 G+ T K + PDII Sbjct: 304 GDISTSAKLRVVVNSKPDII 323 Score = 69.7 bits (163), Expect = 5e-11 Identities = 66/256 (25%), Positives = 102/256 (39%), Gaps = 30/256 (11%) Query: 3544 TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTG 3603 T + L E E G P F D+ + A F+ R+ V+WF + + Sbjct: 93 TAEVLVNEREKGEGPRFEERLRDVRVEIGREASFKVRV----SLPAEVDWFKGEEMIDDT 148 Query: 3604 SRVKTINDF---GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660 R I+D G L I V D G+Y C A N GE+ SCK + ++ I+ PQ Sbjct: 149 GRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGES--SCKANLLLKEEEIVAPQ 206 Query: 3661 LPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVE 3720 + ++ ES ++ P +K+ ++VPE F CRV Sbjct: 207 VLDEVEAAPES----------------SKQRGFAPEILQPLKE-VNVPENDTAIFKCRV- 248 Query: 3721 PVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780 P ++W +G G R+ L I+ D G Y C A N +G + Sbjct: 249 -TASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDIS 307 Query: 3781 TTAK--ITCSAKRDIV 3794 T+AK + ++K DI+ Sbjct: 308 TSAKLRVVVNSKPDII 323 Score = 69.7 bits (163), Expect = 5e-11 Identities = 54/205 (26%), Positives = 85/205 (41%), Gaps = 17/205 (8%) Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGAR---LKSTFDFGLVTLSINSLRNDDSGIYTCKA 2719 EA + R +++WFK + R + D GL LSI+ +R +D G+Y C A Sbjct: 123 EASFKVRVSLPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVA 182 Query: 2720 TNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISH 2779 N +GE+ A++ +++ E + P LD + A + Sbjct: 183 FNEVGESSCKANLLLKEE-----EIVAPQVLDEVEA-------APESSKQRGFAPEILQP 230 Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839 L + E D F+C V S PT +EW + + G R + + +L I Sbjct: 231 LKEVNVPENDTAIFKCRVTASPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQAR 288 Query: 2840 EEDSGIYTCKATNSKGSATTSGSLR 2864 + D G Y C A N+ G +TS LR Sbjct: 289 DTDMGSYKCVARNNFGDISTSAKLR 313 Score = 69.3 bits (162), Expect = 7e-11 Identities = 51/205 (24%), Positives = 92/205 (44%), Gaps = 23/205 (11%) Query: 2944 KIEWYFNGKVLEQGSRFKLT---SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 +++W+ ++++ RF + +D G L + DV D G+Y C A+N+ GE+ Sbjct: 135 EVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGES----- 189 Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060 + K NL+ + + + L++++ +S ++ G PE K+ V++ Sbjct: 190 ---SCKANLLLKEEEIVAPQVLDEVEAAPESSKQR---------GFAPEILQPLKE-VNV 236 Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120 E A ++ + T + +EW +G + RI Y + L I + TD G+ Sbjct: 237 PENDTAIFKCRV--TASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGS 294 Query: 3121 YSCRATNKWGQAEISVKLECVDKSK 3145 Y C A N +G S KL V SK Sbjct: 295 YKCVARNNFGDISTSAKLRVVVNSK 319 Score = 68.1 bits (159), Expect = 2e-10 Identities = 60/233 (25%), Positives = 101/233 (43%), Gaps = 24/233 (10%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI---FRFGY 693 P+F L+ V G + F+ R+ + ++W K + I+ + RF I G Sbjct: 107 PRFEERLRDVRVEIGREASFKVRVSLPAE----VDWFKGEEMIDDTGRFMIIDDDADKGL 162 Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753 L + + +D G Y C A + G + KA L + + P+ L ++ + Sbjct: 163 FQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLKEEEIVA-----PQVLDEVEAAPES 217 Query: 754 SKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI 813 SK Q P+ ++PL+++ + E A F+ ++T PT VEW +DG + Sbjct: 218 SK---------QRGFAPEILQPLKEVN-VPENDTAIFKCRVTASPAPT--VEWLRDGVRV 265 Query: 814 TASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866 T RI + + +L I R D GSY A N G+ ++A +RV S Sbjct: 266 TEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNS 318 Score = 67.7 bits (158), Expect = 2e-10 Identities = 52/194 (26%), Positives = 74/194 (38%), Gaps = 6/194 (3%) Query: 388 KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447 K AP + EG R TG P P V WF + ++ + +ES + Sbjct: 5 KGEAPVITSKLTRVECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDES-S 63 Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507 L+I ++D G CV RN+ G + V E+E+ P+F ER + V G Sbjct: 64 CTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNEREKGEGPRFEERLRDVRVEIGRE 123 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRI---HTDGGASTLDIPRAKASDAAWYQCT 564 R V P + W K I I D G L I + D Y+C Sbjct: 124 ASFKVR-VSLPA-EVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCV 181 Query: 565 AQNVAGSTATRARL 578 A N G ++ +A L Sbjct: 182 AFNEVGESSCKANL 195 Score = 67.7 bits (158), Expect = 2e-10 Identities = 74/255 (29%), Positives = 112/255 (43%), Gaps = 40/255 (15%) Query: 763 EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822 E + + P+F L+D+ ++ GR A F+ + VS P V+W+K I + R I Sbjct: 100 EREKGEGPRFEERLRDV-RVEIGREASFKVR---VSLPA-EVDWFKGEEMIDDTGRFMII 154 Query: 823 ---FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRR 879 + G L+I +R ED G Y A N++GE+ A++ + V P+ Sbjct: 155 DDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLKEEEIVA-----PQVLD 209 Query: 880 YIEKTXXXXXXXXXXXXXXXXXVPESTQK----PEFKTPIKDQISIKEGGFAHFEARLEP 935 +E PES+++ PE P+K+ +++ E A F+ R+ Sbjct: 210 EVE------------------AAPESSKQRGFAPEILQPLKE-VNVPENDTAIFKCRVTA 250 Query: 936 IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995 T VEWL+DG V RI + LTI D G Y C A N G +T Sbjct: 251 SPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDIST 308 Query: 996 SANLTIV--TKKDII 1008 SA L +V +K DII Sbjct: 309 SAKLRVVVNSKPDII 323 Score = 66.5 bits (155), Expect = 5e-10 Identities = 73/278 (26%), Positives = 121/278 (43%), Gaps = 24/278 (8%) Query: 2316 SVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQR 2375 ++K N + T S T+ + +II++ + + EL SA + E + Sbjct: 48 NLKPNNRVSAETDESSCTLIIQEAIINDEGSYRCVVR-NELGSALSTAEVLVNEREKGEG 106 Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR---ITKTHDFG 2432 P F + L+++ ++ G+ A F R V P +V+WF+ E++I+D+ R I D G Sbjct: 107 PRFEERLRDV-RVEIGREASFKVR---VSLPA-EVDWFKGEEMIDDTGRFMIIDDDADKG 161 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQ 2492 ++I VR ED GVY C A N +GE + E P+ + +++ + Sbjct: 162 LFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLK-----EEEIVAPQVLDEVEAAPE 216 Query: 2493 PHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELK 2552 ++R P E +P+ + + P E A ++ RV P+ EW +GV + Sbjct: 217 SSKQRGFAP--EILQPL--KEVNVP----ENDTAIFKCRVT--ASPAPTVEWLRDGVRVT 266 Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G R + TL IN D G Y C A N G Sbjct: 267 EGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFG 304 Score = 66.5 bits (155), Expect = 5e-10 Identities = 65/231 (28%), Positives = 100/231 (43%), Gaps = 31/231 (13%) Query: 2235 EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT 2294 E K PRF LR V G+ A F+ +V + ++++ + + RF I Sbjct: 100 EREKGEGPRFEERLRDV-RVEIGREASFKVRVSLPAE----VDWFKGEEMIDDTGRFMII 154 Query: 2295 ---FDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351 D G L I PED G Y A N +G + K +++ + + + Sbjct: 155 DDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESS--------CKANLLLKEEEIVAPQ 206 Query: 2352 KIRELESAEPFKRPEIPEPVTRQR---PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTL 2408 + E+E+A PE ++QR P QPL+ + N+ E TA F CR+ PT Sbjct: 207 VLDEVEAA--------PES-SKQRGFAPEILQPLKEV-NVPENDTAIFKCRVTASPAPT- 255 Query: 2409 KVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 VEW R+ + + RI + ++TI+ RD D G Y C A N G+ Sbjct: 256 -VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGD 305 Score = 66.1 bits (154), Expect = 7e-10 Identities = 64/229 (27%), Positives = 93/229 (40%), Gaps = 22/229 (9%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT---YDF 2032 E P+F + +++ V G + V+ P V+W+ + RF D Sbjct: 105 EGPRFEERLRDVRVEIGREASFKVR---VSLPA-EVDWFKGEEMIDDTGRFMIIDDDADK 160 Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092 G L I ED G Y C A N VGE SS K + L E+ + Q L+ Sbjct: 161 GLFQLSIDDVRPEDLGVYKCVAFNEVGE----SSCKANL-------LLKEEEIVAPQVLD 209 Query: 2093 KYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152 + E P +Q G P L L + N+ E D A F+CRV P T++W +G ++ Sbjct: 210 EVEAA-PESSKQRGFAPEILQPLKEV-NVPENDTAIFKCRVTA--SPAPTVEWLRDGVRV 265 Query: 2153 RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 G R + L I D G+Y C A N G+ + L+V Sbjct: 266 TEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRV 314 Score = 64.5 bits (150), Expect = 2e-09 Identities = 63/235 (26%), Positives = 102/235 (43%), Gaps = 24/235 (10%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF-- 1899 + PRF +L ++ G+ A ++ R+ P V+W+ +++ R+ +D Sbjct: 105 EGPRFEERLRD-VRVEIGREASFKVRVS-LP---AEVDWFKGEEMIDDTGRFMIIDDDAD 159 Query: 1900 -GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYL 1958 G L I V ED G Y C A N +G+ SS + N+ KE I Q L++++ Sbjct: 160 KGLFQLSIDDVRPEDLGVYKCVAFNEVGE--SSCKANLLLKEEEIVAPQ---VLDEVEAA 214 Query: 1959 EDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGR 2018 + S+ + F P+ +P+K V E + +T PT VEW +G Sbjct: 215 PESSKQR------GFA---PEILQPLKEVNVPENDTAIFKCRVTASPAPT--VEWLRDGV 263 Query: 2019 PVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 V +G R Y L I A D G+Y C A N G+ T++ ++V S Sbjct: 264 RVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNS 318 Score = 60.5 bits (140), Expect = 3e-08 Identities = 57/233 (24%), Positives = 102/233 (43%), Gaps = 21/233 (9%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT---T 322 P+ ++ R+ +++ G +A F+V++S V WFK + + ++ + II Sbjct: 107 PRFEERLRDVRVEIGREASFKVRVS--LPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQ 164 Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382 L + + + D G Y +A N G ES ++ + + + + E E Sbjct: 165 LSIDDVRPEDLGVYKCVAFNEVG----------ESSCKANLLLKEEEIVAPQVLDEVEAA 214 Query: 383 IEIS-EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441 E S ++ AP+ ++ ++ +V E F CRVT P P V W + D +R +I+ Sbjct: 215 PESSKQRGFAPEILQPLKEVNVPENDTAIFKCRVTASPAPTVEW-LRD-GVRVTEGRRIV 272 Query: 442 VNESGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI--EKEQVVAP 491 A L I +D G CVARN G+ + +L V+ K ++ P Sbjct: 273 AQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSKPDIITP 325 Score = 56.4 bits (130), Expect = 5e-07 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 3/100 (3%) Query: 3413 EEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF 3472 + KG+APV T L+ +E + EG+ A R T + P VEW+ +G +LK +R Sbjct: 2 QRPKGEAPVITSKLTRVECV-EGDKATLSVRFTGSPTPT--VEWFKDGMNLKPNNRVSAE 58 Query: 3473 CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 D L I D G Y C N G A++TA + V Sbjct: 59 TDESSCTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLV 98 Score = 56.4 bits (130), Expect = 5e-07 Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 17/173 (9%) Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQL 2621 D G L I+ V D G+Y C A N G ++ + P+ +++ Sbjct: 159 DKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLKE-----EEIVAPQVLDEV-- 211 Query: 2622 KEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKN 2681 EAA PE G AP LK + + E + +V P +EW ++ Sbjct: 212 -EAA----PESSKQRGF--APEILQPLKEVN-VPENDTAIFKCRVTASPAPT--VEWLRD 261 Query: 2682 GVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 GV +T G R+ + + + TL+IN R+ D G Y C A N G+ ++A +++ Sbjct: 262 GVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRV 314 Score = 55.2 bits (127), Expect = 1e-06 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +AP+ T+ L + VEG L + P +EWFK+G+ L R+ + D Sbjct: 7 EAPVITSKLTRVE-CVEGDKATLSVRFTGSPTPT--VEWFKDGMNLKPNNRVSAETDESS 63 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 TL I +D G Y C N LG A+STA + + +R Sbjct: 64 CTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101 Score = 54.8 bits (126), Expect = 2e-06 Identities = 62/240 (25%), Positives = 98/240 (40%), Gaps = 26/240 (10%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 + P+F L ++ G + R+ + V+WF + I RF + Sbjct: 105 EGPRFEERLRDVRVEIGREASFKVRVSLPAE----VDWFKGEEMIDDTGRFMIIDDDADK 160 Query: 1369 ALDLLS---VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425 L LS V PED GVY C A N++GE+ SC ++ K++ I+ P L++++ Sbjct: 161 GLFQLSIDDVRPEDLGVYKCVAFNEVGES--SCKANLLLKEEEIVA---PQVLDEVEAAP 215 Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485 ++S+ + P + K + NV E F+C++ VEW ++G Sbjct: 216 ESSKQRG---------FAPEILQPLKEV-NVPENDTAIFKCRV--TASPAPTVEWLRDGV 263 Query: 1486 PVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC--RLTCRSTTDIV 1543 VT G R + L I D G Y C A N G S R+ S DI+ Sbjct: 264 RVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSKPDII 323 Score = 52.8 bits (121), Expect = 7e-06 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 3/96 (3%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 G+ PV + LT +E + EGD+A R P T++WF +G ++ +R D Sbjct: 6 GEAPVITSKLTRVECV-EGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDES 62 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 L I D G+Y C N+LG A++T + V Sbjct: 63 SCTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLV 98 Score = 52.8 bits (121), Expect = 7e-06 Identities = 49/204 (24%), Positives = 81/204 (39%), Gaps = 21/204 (10%) Query: 1211 VEWFHNGRSVTVGSRFKTY---YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267 V+WF + RF D G L I D G Y A N +G + A + Sbjct: 136 VDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANL 195 Query: 1268 RVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTN 1327 +++ +IV Q +++++ +++++ AP+ + L + E Sbjct: 196 -LLKEEEIVAP----QVLDEVEAAPESSKQRGF---------APEILQPLKEVNVPENDT 241 Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQA 1387 +CR+ T VEW +G + G R Y + L + D G Y C A Sbjct: 242 AIFKCRVTASPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVA 299 Query: 1388 TNQLGEAVTSCALRVI--AKKDLI 1409 N G+ TS LRV+ +K D+I Sbjct: 300 RNNFGDISTSAKLRVVVNSKPDII 323 Score = 52.0 bits (119), Expect = 1e-05 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 2/97 (2%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 +APV T + + E A R G P VEW ++G+ ++ +NR++ D Sbjct: 7 EAPVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESSC 64 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 L ++ D G+Y C NELG A++++ + V + Sbjct: 65 TLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101 Score = 51.2 bits (117), Expect = 2e-05 Identities = 52/199 (26%), Positives = 82/199 (41%), Gaps = 22/199 (11%) Query: 4006 KVEWFFNGKPLLHKNRFTPI---YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAV 4062 +V+WF + + RF I D G ++ V PED G Y C A N G KA Sbjct: 135 EVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKAN 194 Query: 4063 IKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTV 4122 + ++ + ++ + + + E+EA+ PE + + P + L + V V Sbjct: 195 L-------LLKEEEIV----APQVLDEVEAA----PES--SKQRGFAPEILQPLKE-VNV 236 Query: 4123 EEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTGKIE 4181 E + A F CRVT P P V WL +G + G R Y D + I + R D G + Sbjct: 237 PENDTAIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYK 296 Query: 4182 VIXXXXXXXXXXXXXLKVI 4200 + L+V+ Sbjct: 297 CVARNNFGDISTSAKLRVV 315 Score = 50.8 bits (116), Expect = 3e-05 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%) Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635 +AP+ T+ L VE EG +A R T VEW+ + LK +R + + Sbjct: 7 EAPVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESSC 64 Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673 L I + D G+Y C N LG A+++ +V+ ++ Sbjct: 65 TLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNERE 102 Score = 49.2 bits (112), Expect = 8e-05 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840 E EG A + T PT VEW+KDG + ++R+++ + +L I D Sbjct: 19 ECVEGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDE 76 Query: 841 GSYTVRAVNKLGEAISTASIRVAAR 865 GSY N+LG A+STA + V R Sbjct: 77 GSYRCVVRNELGSALSTAEVLVNER 101 Score = 49.2 bits (112), Expect = 8e-05 Identities = 59/249 (23%), Positives = 97/249 (38%), Gaps = 38/249 (15%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVE-PKEDPKLRIEWYRNGKLLPSGHRYRTV---YDMG 3885 P+F +++ VE F+ RV P E ++W++ +++ R+ + D G Sbjct: 107 PRFEERLRDVRVEIGREASFKVRVSLPAE-----VDWFKGEEMIDDTGRFMIIDDDADKG 161 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945 L I V ED G Y C A N+ GE KA + K+ + I+ QV L + Sbjct: 162 LFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLKE--EEIVAPQV---------LDE 210 Query: 3946 MEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNM 4005 +EA + + E + Q + ++ E +T F+C++ P Sbjct: 211 VEAAPESSKQRGFAPE--------------ILQPLKEVNVPENDTAIFKCRVT--ASPAP 254 Query: 4006 KVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK- 4064 VEW +G + R Y + D G Y C A N +G T A ++ Sbjct: 255 TVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRV 314 Query: 4065 -TTGKPGIV 4072 KP I+ Sbjct: 315 VVNSKPDII 323 Score = 48.4 bits (110), Expect = 1e-04 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 3/97 (3%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 RP +P I ++ + +G A + G+PTP V W + L N+ S +E Sbjct: 3 RPKGEAPVITSKLTR-VECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDE 61 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161 + +L+I++ DEG Y C RN+ G A+ + + Sbjct: 62 SS--CTLIIQEAIINDEGSYRCVVRNELGSALSTAEV 96 Score = 47.6 bits (108), Expect = 2e-04 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 2/97 (2%) Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 E P + E EG L T PT VEW+ +G ++ +R D Sbjct: 7 EAPVITSKLTRVECVEGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDESSC 64 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 L I A D G+Y C N +G A++T+ V V+ + Sbjct: 65 TLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101 Score = 47.6 bits (108), Expect = 2e-04 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 2/94 (2%) Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 +AP + L +E VEG L R G T VEWF +G +K +R + Sbjct: 7 EAPVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESSC 64 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + D G Y C N+LG A+++ + V Sbjct: 65 TLIIQEAIINDEGSYRCVVRNELGSALSTAEVLV 98 Score = 45.6 bits (103), Expect = 0.001 Identities = 29/85 (34%), Positives = 36/85 (42%), Gaps = 3/85 (3%) Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565 E P+ T LT E EG A R G P+ EW+ +G+ LK +R D Sbjct: 7 EAPVITSKLTRV-ECVEGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDESS 63 Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590 TL I + ND G Y C N G Sbjct: 64 CTLIIQEAIINDEGSYRCVVRNELG 88 Score = 45.2 bits (102), Expect = 0.001 Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 6/99 (6%) Query: 907 QKPEFKTPI----KDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962 Q+P+ + P+ ++ EG A R G T VEW KDG ++ ++R++ Sbjct: 2 QRPKGEAPVITSKLTRVECVEGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAET 59 Query: 963 NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 + L I+ ++D G Y C N +G A ++A + + Sbjct: 60 DESSCTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLV 98 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 3/85 (3%) Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433 + PV T L ++ + EG A R G PT VEWF++ ++ ++R++ D Sbjct: 7 EAPVITSKLTRVECV-EGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESS 63 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458 ++ I DEG Y C N LG Sbjct: 64 CTLIIQEAIINDEGSYRCVVRNELG 88 Score = 44.0 bits (99), Expect = 0.003 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P Q K + A F+ ++ +P P V W R + E + +Y ++ +L Sbjct: 225 PEILQPLKEVNVPENDTAIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYLDEVA--TL 282 Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162 I Q D G Y C ARN +G+ S ++ Sbjct: 283 TINQARDTDMGSYKCVARNNFGDISTSAKLR 313 Score = 43.6 bits (98), Expect = 0.004 Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 2/89 (2%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 V S L + C EGD S PT +EWF + L R + D S +L Sbjct: 10 VITSKLTRVECVEGDKATLSVRFTGSPTPT--VEWFKDGMNLKPNNRVSAETDESSCTLI 67 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 I D G Y C N GSA ++ + Sbjct: 68 IQEAIINDEGSYRCVVRNELGSALSTAEV 96 Score = 43.6 bits (98), Expect = 0.004 Identities = 21/63 (33%), Positives = 29/63 (46%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 G PT ++WF +G +RV D L I D G Y C N+ GSA +T Sbjct: 34 GSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEGSYRCVVRNELGSALST 93 Query: 3783 AKI 3785 A++ Sbjct: 94 AEV 96 Score = 43.2 bits (97), Expect = 0.005 Identities = 34/96 (35%), Positives = 41/96 (42%), Gaps = 3/96 (3%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 PV L+ V EG L R G PT VEWF +G ++ +R D Sbjct: 9 PVITSKLTRVECV-EGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDESSCT 65 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 L I A D G Y N LGSA ++A V V ER Sbjct: 66 LIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101 Score = 42.7 bits (96), Expect = 0.007 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 2/83 (2%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 EG A R P P VEW+ +G L+ +R D L I D G Y Sbjct: 22 EGDKATLSVRFTGSPTPT--VEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEGSY 79 Query: 1918 TCKAINNLGQAVSSIRLNVQSKE 1940 C N LG A+S+ + V +E Sbjct: 80 RCVVRNELGSALSTAEVLVNERE 102 Score = 41.5 bits (93), Expect = 0.016 Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 2/83 (2%) Query: 1056 VEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGV 1115 VEG A R T TVEW+ +G + NR+ D L I D G Sbjct: 21 VEGDKATLSVRFTGSP--TPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEGS 78 Query: 1116 YTVVARNAAGEAQLSASMTVETR 1138 Y V RN G A +A + V R Sbjct: 79 YRCVVRNELGSALSTAEVLVNER 101 Score = 39.9 bits (89), Expect = 0.049 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 2/95 (2%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P L V +EG K R G PT +EW K+G +++ ++R ++ +L Sbjct: 9 PVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTL 66 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 + I D G Y C + G A + A + V R Sbjct: 67 IIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101 Score = 39.1 bits (87), Expect = 0.086 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 11/134 (8%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 + VEG L V P +EW+ +G L+ +R +D TL + + D Sbjct: 19 ECVEGDKATLS--VRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDE 76 Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKD-----NLIERTQHPKGTEGLEKIQNLEDSLRKE- 3035 G Y C N+ G A +++ V ++ ER + + G E + SL E Sbjct: 77 GSYRCVVRNELGSALSTAEVLVNEREKGEGPRFEERLRDVRVEIGREASFKVRVSLPAEV 136 Query: 3036 ---PGQQPDDDTGR 3046 G++ DDTGR Sbjct: 137 DWFKGEEMIDDTGR 150 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE-QTGDVS 130 P FE+ ++ R G A F K+R + V W + + + + ++ + ++ G Sbjct: 107 PRFEERLRDVRVEIGREASF--KVRVSLPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQ 164 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAIC 157 L I + P D G Y C A N+ GE+ C Sbjct: 165 LSIDDVRPEDLGVYKCVAFNEVGESSC 191 Score = 34.3 bits (75), Expect = 2.5 Identities = 26/99 (26%), Positives = 36/99 (36%), Gaps = 2/99 (2%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G P T+ + + E A R + VEWF +G L +RV D Sbjct: 6 GEAPVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESS 63 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653 L I D G Y C N G A + ++ V R+ Sbjct: 64 CTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNERE 102 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/79 (26%), Positives = 31/79 (39%) Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900 VE EG + V P +EW+++G L +R D +L I D G Sbjct: 18 VECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEG 77 Query: 3901 EYICRAVNDFGEDFTKATI 3919 Y C N+ G + A + Sbjct: 78 SYRCVVRNELGSALSTAEV 96 >SB_54054| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 4232 Score = 116 bits (279), Expect = 5e-25 Identities = 102/396 (25%), Positives = 147/396 (37%), Gaps = 43/396 (10%) Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477 QP VF + F P I W ++ I T S S L + V D Sbjct: 601 QPKSVFTGDDVTFTCNATALAAPSIWWQKDGVNI---------TISDGSTLNLVNVKEGD 651 Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537 S + VAE T A + + +PP T N + V + Sbjct: 652 SGNYTCVAEAGENTTTSDAAFLSVK---------LPPVITNHPANQTANKDENVTIACSA 702 Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 GT+P +V WLKN + +++ E TL I P D G Y+C N Sbjct: 703 NGTEPFNVIWLKNNEVYDFSSDSRVHESHNNLTLEIFGVLPNDHGSYQCDVSNGR----- 757 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 DK P T P+ I K K EGQ ++F C+ G P P V W Sbjct: 758 -----------TDKSYPGTLIVKYAPQFIVEPKGKTTTEGQVVKFECQTTGNPSPNVTWL 806 Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717 K + S +++ L I+ D G Y C A N G ++ A L V + Sbjct: 807 KSGSAVNTS--VDPRFYSNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPE 864 Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777 N+P +D EG F+ PT+ WL+ G+ + + D + G + Sbjct: 865 FVNVP-----QDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALNTSVDPRFYSNGTH-- 917 Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 L+I N D+G + C A++ G + T A L V K Sbjct: 918 LMITNVNRTDSGAYRCNASSILGVITTKASLDVYFK 953 Score = 114 bits (274), Expect = 2e-24 Identities = 109/405 (26%), Positives = 167/405 (41%), Gaps = 49/405 (12%) Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 KP I T P V E E +G P P +W++++ P + + ++ L Sbjct: 1137 KPDISTHP-SPQTVTEGENVTLSCAAEGRPTPSYQWFKDDSPFDAGNNARASL--SEGNL 1193 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCS-ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 I +V +D + +A N S L V PS T QN Sbjct: 1194 IFTKVSRDDHGQYYCLANNSVSNVTSSKVQLTV----------FFAPSITTHPQNQTKVE 1243 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 G++V L VTG VYW ++G + +R + + + TL I +D G Y C Sbjct: 1244 GEIVTLSCTVTGDPVPTVYWSRDGSNLTA-LRYLV---EPSNTLKIENLTREDEGSYICH 1299 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKI 4646 A N+ DA + N PP+ +E LK K E + +CK+ Sbjct: 1300 AFNNVSSTSSDAAVLT---------------VNYPPKFLESLKPKETRNETDNLTLTCKL 1344 Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTAD----EYTLRISEAFPEDEGDYKCVAYNSAG 4702 GKP TV W K + +KP +++ + E TL I DE YKC A N+ G Sbjct: 1345 EGKPQATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINLDRSDEASYKCRANNTVG 1404 Query: 4703 RVTVA-AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761 VT + + V P + +P +++ EG Q+ K K ++ WL G+L+ Sbjct: 1405 IVTSSNTTVTVQYPPKFFKIPD-----NVIKTEGSSVNLTCQLECKPKCSVTWLIGGSLL 1459 Query: 4762 PETPD----FQMIHEGNN-AVLLIGNTYEEDTGTFTCRATTAAGQ 4801 + D Q ++GN + L+I N D ++TCRA AAG+ Sbjct: 1460 DTSSDRISVTQPENDGNETSFLMISNLNRTDEASYTCRAKNAAGE 1504 Score = 101 bits (242), Expect = 1e-20 Identities = 108/423 (25%), Positives = 171/423 (40%), Gaps = 55/423 (13%) Query: 4402 EGPVKPSKPPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 +G + + PP F + ++P E + + +G+PL + W ++N +K PD Sbjct: 1951 QGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELK--PD---- 2004 Query: 4461 TFSTKSILIIRQVFVEDS--AVFAAVAENRGGTA--KCSANLVVEEKRRQGRGGIV---P 4513 S LII Q DS + + NR A KC AN V+ +V P Sbjct: 2005 -----SRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYP 2059 Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY---- 4569 P F + +N VT V L ++ V WLK+ + + G+Y Sbjct: 2060 PKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTT 2119 Query: 4570 -TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628 +L I D +Y C AIN+AGE + + N PP+ +E Sbjct: 2120 SSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLT---------------VNYPPKFLES 2164 Query: 4629 LK-DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR----TADEYTLRIS 4683 LK ++ E + +CK+ GKPL TV W K + +KP +++ + E TL+I Sbjct: 2165 LKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKII 2224 Query: 4684 EAFPEDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742 DE YKC A N+ + + V P + P +D V E Sbjct: 2225 NVNRHDEAYYKCRANNTVNTTASTNTSVVVQYPPKFFQSP-----KDKTVTEKSDVTLTC 2279 Query: 4743 QITSKIKPTIQWLREGALIPETP-DFQMIHEGN----NAVLLIGNTYEEDTGTFTCRATT 4797 Q+ K K ++ WL++ + +P + H G+ + L I N D ++C+A Sbjct: 2280 QLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAIN 2339 Query: 4798 AAG 4800 AAG Sbjct: 2340 AAG 2342 Score = 99.1 bits (236), Expect = 8e-20 Identities = 102/391 (26%), Positives = 150/391 (38%), Gaps = 45/391 (11%) Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483 E + +FE + G P P + W + + S D + +S +IL+I V DS ++ Sbjct: 785 EGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVDPRF--YSNDTILMITNVSRIDSGTYSC 842 Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543 A N G A L V R G P F Q+ G V + G P Sbjct: 843 NASNELGIISAEAALDV----RYG------PEFVNVPQDKTPNEGWSVTFECHTKGNPPP 892 Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603 V WLKNG + + + +GT+ L+I DSG Y C A + G A V Sbjct: 893 TVTWLKNGSALNTSVDPRFYS-NGTH-LMITNVNRTDSGAYRCNASSILGVITTKASLDV 950 Query: 4604 SL-PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662 P P PQT V EGQ + C G+P P+ QW+K D Sbjct: 951 YFKPDISTHPSPQT-----------------VTEGQNVTLLCVAEGRPTPSYQWFKDDSP 993 Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA-AKLKVTQPDQADNL 4721 + S E L ++ +D G Y C+A NS VT + A+L V Sbjct: 994 FDAENNTRAS--LSEGNLIFTKISRDDHGQYYCLANNSVSNVTSSIAQLNVFFKPDISTY 1051 Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ-MIHEGNNAVLLI 4780 P+ + EG+ + P+ QW ++ + + + + EGN L+ Sbjct: 1052 PS-----PQTITEGENVTLLCVAEGRPSPSYQWFKDDSPFDAKYNTRASLSEGN---LIF 1103 Query: 4781 GNTYEEDTGTFTCRATTAAGQVETS-AKLVV 4810 +D G + C A + V +S AKL V Sbjct: 1104 TKVSRDDHGQYYCLANNSVSNVTSSIAKLTV 1134 Score = 98.7 bits (235), Expect = 1e-19 Identities = 57/188 (30%), Positives = 93/188 (49%), Gaps = 10/188 (5%) Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 APQF+ + + TEG++ +F+C+ TG P P VTW + + + + N++ L Sbjct: 771 APQFIVEPKGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVDPRFYSNDT---IL 827 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 MITNV+ DSG +C A N+ G + + L+V P+FV EG V Sbjct: 828 MITNVSRIDSGTYSCNASNELGIISAEAALDV-----RYGPEFVNVPQDKTPNEGWSVTF 882 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 G P P +TW K+G + + + R +++G + L I +D+ Y+C A ++ G Sbjct: 883 ECHTKGNPPPTVTWLKNGSALNTSVDPRFYSNG--THLMITNVNRTDSGAYRCNASSILG 940 Query: 571 STATRARL 578 T+A L Sbjct: 941 VITTKASL 948 Score = 96.7 bits (230), Expect = 4e-19 Identities = 107/416 (25%), Positives = 166/416 (39%), Gaps = 55/416 (13%) Query: 4410 PPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI------HTF 4462 PP F + ++P E + + +G+P + W ++N +K PD ++ Sbjct: 1319 PPKFLESLKPKETRNETDNLTLTCKLEGKPQATVVWLKDNTELK--PDSRLIITQPSSVD 1376 Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522 S +S L I + D A + A N G S V + PP F N Sbjct: 1377 SGESTLTIINLDRSDEASYKCRANNTVGIVTSSNTTVTVQ---------YPPKFFKIPDN 1427 Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDI-RNKIL--EEDGTYT--LLILEAY 4577 V T G V L ++ V WL G + R + E DG T L+I Sbjct: 1428 VIKTEGSSVNLTCQLECKPKCSVTWLIGGSLLDTSSDRISVTQPENDGNETSFLMISNLN 1487 Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK-IVAE 4636 D Y C A N+AGE + V+L A N PP+ ++ LKD+ + E Sbjct: 1488 RTDEASYTCRAKNAAGEKTSGS---VNL------------AVNYPPKFLQSLKDEETLNE 1532 Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD----EYTLRISEAFPEDEGD 4692 + +CK+ GKPL TV W K + ++P +++ + E TL I DE Sbjct: 1533 TDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAY 1592 Query: 4693 YKCVAYNSAGRVTVAAKLKVT--QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750 YKC+A N+ T V P + P ++ V E Q+ K K Sbjct: 1593 YKCLANNTVDTTTSTTNTSVVVQYPPKFFQSP-----KNETVTEKSNVTLTCQLECKPKC 1647 Query: 4751 TIQWLREGALIPETPD-FQMIHEGN----NAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 ++ WL++ + +PD + H G+ + L I N D ++C+A AAG+ Sbjct: 1648 SVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGE 1703 Score = 84.2 bits (199), Expect = 2e-15 Identities = 63/188 (33%), Positives = 79/188 (42%), Gaps = 11/188 (5%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P+FV V QD+ EG F+C G P P VTW N + + + N G H LM Sbjct: 863 PEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALNTSVDPRFYSN--GTH-LM 919 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511 ITNV +DSG C A + G + L+V K P S V EG+ V L Sbjct: 920 ITNVNRTDSGAYRCNASSILGVITTKASLDVYFK-----PDISTHPSPQTVTEGQNVTLL 974 Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN-VAG 570 A G PTP W KD P R G L + D Y C A N V+ Sbjct: 975 CVAEGRPTPSYQWFKDDSPFDAENNTRASLSEG--NLIFTKISRDDHGQYYCLANNSVSN 1032 Query: 571 STATRARL 578 T++ A+L Sbjct: 1033 VTSSIAQL 1040 Score = 79.8 bits (188), Expect = 5e-14 Identities = 95/407 (23%), Positives = 153/407 (37%), Gaps = 51/407 (12%) Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 KP I T P V E + +G P P +W++++ P D + +T ++ S Sbjct: 953 KPDISTHP-SPQTVTEGQNVTLLCVAEGRPTPSYQWFKDDSPF----DAENNTRASLS-- 1005 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVT 4526 E + +F ++ + G C AN V P + +T Sbjct: 1006 -------EGNLIFTKISRDDHGQYYCLANNSVSNVTSSIAQLNVFFKPDISTYPSPQTIT 1058 Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586 G+ V L G W K+ + +G L+ + D G+Y C Sbjct: 1059 EGENVTLLCVAEGRPSPSYQWFKDDSPFDAKYNTRASLSEGN--LIFTKVSRDDHGQYYC 1116 Query: 4587 VAINSAGEARCD-AECVVSL-PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644 +A NS A+ V P P PQT V EG+ + SC Sbjct: 1117 LANNSVSNVTSSIAKLTVFFKPDISTHPSPQT-----------------VTEGENVTLSC 1159 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 G+P P+ QW+K D + S E L ++ +D G Y C+A NS V Sbjct: 1160 AAEGRPTPSYQWFKDDSPFDAGNNARAS--LSEGNLIFTKVSRDDHGQYYCLANNSVSNV 1217 Query: 4705 TVAAKLKVTQPDQADNLPALT--PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 T ++K+++T P++T P V EG+ +T PT+ W R+G+ + Sbjct: 1218 T-SSKVQLT----VFFAPSITTHPQNQTKV-EGEIVTLSCTVTGDPVPTVYWSRDGSNLT 1271 Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809 + + E +N L I N ED G++ C A + A ++ Sbjct: 1272 A---LRYLVEPSN-TLKIENLTREDEGSYICHAFNNVSSTSSDAAVL 1314 Score = 79.0 bits (186), Expect = 9e-14 Identities = 103/432 (23%), Positives = 167/432 (38%), Gaps = 71/432 (16%) Query: 4410 PPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI------HTF 4462 PP F + ++ E + + +G+PL + W ++N ++ PD ++ Sbjct: 1517 PPKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVWLKDNTELE--PDSRLIITQPSSVD 1574 Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522 S +S L I V D A + +A N T + N V + PP F + +N Sbjct: 1575 SGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQ--------YPPKFFQSPKN 1626 Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY-----TLLILEAY 4577 VT V L ++ V WLK+ + + G+Y +L I Sbjct: 1627 ETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLV 1686 Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637 D +Y C AIN+AGE + + N PP+I+ P K+ + EG Sbjct: 1687 RTDEARYSCKAINAAGEKTSEQGLLT---------------VNYPPKILTPPKNVTITEG 1731 Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA----DEYTLRISEAFPEDEGDY 4693 + SC++ GKP TV W G I+ S + + A L I EG Y Sbjct: 1732 NDVTLSCEVEGKPEVTVDWLNGSTPIELSSVIEKTGLAVTGIGLSNLTIKGVSRYYEGSY 1791 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ---ITSKI-- 4748 KC A PD +++ PA + + + + + +T +T K+ Sbjct: 1792 KCRAKR--------------DPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTCKLEG 1837 Query: 4749 KP--TIQWLREGALIPETPDFQMI------HEGNNAVLLIGNTYEEDTGTFTCRA-TTAA 4799 KP T+ WL++ + PD ++I E + L I N D + CRA T Sbjct: 1838 KPLATVVWLKDNTEL--KPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVN 1895 Query: 4800 GQVETSAKLVVK 4811 T+ +VV+ Sbjct: 1896 TTASTNTSVVVQ 1907 Score = 76.2 bits (179), Expect = 6e-13 Identities = 67/254 (26%), Positives = 105/254 (41%), Gaps = 32/254 (12%) Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627 T +L I D +Y C AIN+AGE + + N PP+ +E Sbjct: 1920 TSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLT---------------VNYPPKFLE 1964 Query: 4628 PLK-DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD----EYTLRI 4682 LK ++ E + +CK+ GKPL TV W K + +KP +++ + E TL I Sbjct: 1965 SLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTI 2024 Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT--QPDQADNLPALTPLRDIVVYEGQPAQF 4740 DE YKC A N+ T V P + P ++ V E Sbjct: 2025 INVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYPPKFFQSP-----KNETVTEKSNVTL 2079 Query: 4741 KTQITSKIKPTIQWLREGALIPETPD-FQMIHEGN----NAVLLIGNTYEEDTGTFTCRA 4795 Q+ K K ++ WL++ + +PD + H G+ + L I N D ++C+A Sbjct: 2080 TCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKA 2139 Query: 4796 TTAAGQVETSAKLV 4809 AAG+ + L+ Sbjct: 2140 INAAGEKSSEQGLL 2153 Score = 75.8 bits (178), Expect = 8e-13 Identities = 81/322 (25%), Positives = 126/322 (39%), Gaps = 45/322 (13%) Query: 265 PPKIAQ--KPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 PPK + KP ++ E + +L G P V W K+ L ++ Sbjct: 1959 PPKFLESLKPEETR-NETDNLTLTCKLEGKPLATVVWLKDNTELKPDSR----------- 2006 Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382 L + DSG TL N N E+Y + R+ DT T Sbjct: 2007 LIITQPSSVDSGESTLTIINVN------------RHDEAYYKC-RANNTVDTTTSTTNTS 2053 Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 + + P+F + ++ VTE C++ +P VTW + D D +I V Sbjct: 2054 VVVQ---YPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTW-LKDNTPLDTSPDRITV 2109 Query: 443 NESGNH-----ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497 G++ +L ITN+ +D +C A N +GE + + L + PKF+E Sbjct: 2110 THPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN----YPPKFLESL 2165 Query: 498 STLNVR-EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH----TDGGASTLDIPR 552 R E + + L + G P + W KD + P+ L I + G STL I Sbjct: 2166 KPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIIN 2225 Query: 553 AKASDAAWYQCTAQNVAGSTAT 574 D A+Y+C A N +TA+ Sbjct: 2226 VNRHDEAYYKCRANNTVNTTAS 2247 Score = 75.4 bits (177), Expect = 1e-12 Identities = 60/196 (30%), Positives = 88/196 (44%), Gaps = 21/196 (10%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE---SGNH 448 P+F K+ + TEG C++ +P VTW I + D + +I V + GN Sbjct: 1419 PKFFKIPDNVIKTEGSSVNLTCQLECKPKCSVTWLIGG-SLLDTSSDRISVTQPENDGNE 1477 Query: 449 A--LMITNVTLSDSGVVTCVARNKSGE-TAFQCRLNVIEKEQVVAPKFVERFS---TLNV 502 LMI+N+ +D TC A+N +GE T+ L V PKF++ TLN Sbjct: 1478 TSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVN-----YPPKFLQSLKDEETLN- 1531 Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI----HTDGGASTLDIPRAKASDA 558 E + + L + G P + W KD + P+ L I D G STL I D Sbjct: 1532 -ETDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDE 1590 Query: 559 AWYQCTAQNVAGSTAT 574 A+Y+C A N +T + Sbjct: 1591 AYYKCLANNTVDTTTS 1606 Score = 74.1 bits (174), Expect = 2e-12 Identities = 101/425 (23%), Positives = 154/425 (36%), Gaps = 56/425 (13%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-----ST 4464 PP F + + V E + + +P + W ++N P+ SPD T +T Sbjct: 2059 PPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNT 2118 Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQN 4522 S L I + D A ++ A N G L+ PP F +L + Sbjct: 2119 TSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN---------YPPKFLESLKPEE 2169 Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI----LEEDGTYTLLILEAYP 4578 + L L K+ G V WLK+ +++PD R I L E G TL I+ Sbjct: 2170 TRNETDNLT-LTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNR 2228 Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638 D Y+C A N+ VV PP+ + KDK V E Sbjct: 2229 HDEAYYKCRANNTVNTTASTNTSVV---------------VQYPPKFFQSPKDKTVTEKS 2273 Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY-----TLRISEAFPEDEGDY 4693 + +C++ KP +V W K + + S + +L I+ DE Y Sbjct: 2274 DVTLTCQLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARY 2333 Query: 4694 KCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK---IK 4749 C A N+AG + + L V P + A R+ EGQ F + K Sbjct: 2334 SCKAINAAGDKTSEQGLLTVNFPPRIFKTSA-NQTRE----EGQQITFTCDVEGKEGTSP 2388 Query: 4750 PTIQWLREGALIPETPDFQMIHEGNN------AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803 P + W ++GA + + N A L I N ED G + C A + V Sbjct: 2389 PNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSLKTVY 2448 Query: 4804 TSAKL 4808 ++ + Sbjct: 2449 STPSI 2453 Score = 73.3 bits (172), Expect = 4e-12 Identities = 57/178 (32%), Positives = 75/178 (42%), Gaps = 12/178 (6%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 +TEG+ C GRP P WF +D YN + ++E GN L+ T V+ D G Sbjct: 1057 ITEGENVTLLCVAEGRPSPSYQWFKDDSPFDAKYNTRASLSE-GN--LIFTKVSRDDHGQ 1113 Query: 463 VTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521 C+A N S T+ +L V K P S V EGE V L+ A G PTP Sbjct: 1114 YYCLANNSVSNVTSSIAKLTVFFK-----PDISTHPSPQTVTEGENVTLSCAAEGRPTPS 1168 Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN-VAGSTATRARL 578 W KD P R G L + D Y C A N V+ T+++ +L Sbjct: 1169 YQWFKDDSPFDAGNNARASLSEG--NLIFTKVSRDDHGQYYCLANNSVSNVTSSKVQL 1224 Score = 72.5 bits (170), Expect = 8e-12 Identities = 60/215 (27%), Positives = 87/215 (40%), Gaps = 18/215 (8%) Query: 364 QDQRSQYI---TDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPY 420 +D QY ++ T +++++ AP Q++ EG++ C VTG P Sbjct: 1200 RDDHGQYYCLANNSVSNVTSSKVQLTV-FFAPSITTHPQNQTKVEGEIVTLSCTVTGDPV 1258 Query: 421 PEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480 P V W R + + LV S + L I N+T D G C A N T+ + Sbjct: 1259 PTVYW---SRDGSNLTALRYLVEPS--NTLKIENLTREDEGSYICHAFNNVSSTSSDAAV 1313 Query: 481 NVIEKEQVVAPKFVERFSTLNVR-EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539 + PKF+E R E + + L + G P + W KD + P+ L I Sbjct: 1314 LTVN----YPPKFLESLKPKETRNETDNLTLTCKLEGKPQATVVWLKDNTELKPDSRLII 1369 Query: 540 ----HTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 D G STL I SD A Y+C A N G Sbjct: 1370 TQPSSVDSGESTLTIINLDRSDEASYKCRANNTVG 1404 Score = 71.7 bits (168), Expect = 1e-11 Identities = 109/497 (21%), Positives = 183/497 (36%), Gaps = 56/497 (11%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 G+P P V W+R + L ++RY + + +L I+ + DEG Y C A N Sbjct: 1255 GDPVPTVYWSRDGSNLT-----ALRYLVEPSN-TLKIENLTREDEGSYICHAFNNVSSTS 1308 Query: 157 CSVYIQPEGXXXXXXXXXXXXXYRHVSE--TVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214 + R+ ++ T+ K G T + ++ + Sbjct: 1309 SDAAVLTVNYPPKFLESLKPKETRNETDNLTLTCKLEGKPQATVVWLKDNTELKPDSRL- 1367 Query: 215 HSSTDDFKVDTFEYRL-LREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273 T VD+ E L + + + + + + V I T + ++ PPK + P Sbjct: 1368 -IITQPSSVDSGESTLTIINLDRSDEASYKCRANNTVGIVTSSNTTVTVQYPPKFFKIPD 1426 Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N EG+ QL P+ VTW G L S+ R+ TQ + Sbjct: 1427 NVIKTEGSSVNLTCQLECKPKCSVTWLIGGSLLDTSSD------------RISVTQPEND 1474 Query: 334 GHYT--LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391 G+ T L+ N N + SY ++ +T + ++ Sbjct: 1475 GNETSFLMISNLN-----------RTDEASYTCRAKN-----AAGEKTSGSVNLAVN-YP 1517 Query: 392 PQFVKVCQDRD-VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN----ESG 446 P+F++ +D + + E C++ G+P V W ++ ++ D + I+ +SG Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVWLKDNTELEPD-SRLIITQPSSVDSG 1576 Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506 L I NV D C+A N T +V+ + PKF + V E Sbjct: 1577 ESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQ---YPPKFFQSPKNETVTEKS 1633 Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA-----STLDIPRAKASDAAWY 561 V L + P +TW KD P+ +P+ T G+ S+L I +D A Y Sbjct: 1634 NVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARY 1693 Query: 562 QCTAQNVAGSTATRARL 578 C A N AG + L Sbjct: 1694 SCKAINAAGEKTSEQGL 1710 Score = 70.1 bits (164), Expect = 4e-11 Identities = 77/337 (22%), Positives = 131/337 (38%), Gaps = 39/337 (11%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-----ST 4464 PP F + + V E + + +P + W ++N P+ SPD T +T Sbjct: 1617 PPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNT 1676 Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524 S L I + D A ++ A N G L+ PP +NV Sbjct: 1677 TSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVN---------YPPKILTPPKNVT 1727 Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584 +T G V L +V G + V WL ++ + ++E+ G L + + Sbjct: 1728 ITEGNDVTLSCEVEGKPEVTVDWLNGSTPIE---LSSVIEKTG----LAVTGIGLSNLTI 1780 Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIVAEGQAIEFS 4643 + V+ G +C A+ +D ++ A + LK ++ E + + Sbjct: 1781 KGVSRYYEGSYKCRAK--------RDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLT 1832 Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSR----TADEYTLRISEAFPEDEGDYKCVAYN 4699 CK+ GKPL TV W K + +KP +++ + E TL+I DE YKC A N Sbjct: 1833 CKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANN 1892 Query: 4700 SAG-----RVTVAAKLKVTQPDQADNLPALTPLRDIV 4731 + +V ++ VT P N + + ++V Sbjct: 1893 TVNTTASTNTSVVVQITVTHPGSYGNTTSSLTITNLV 1929 Score = 68.1 bits (159), Expect = 2e-10 Identities = 88/375 (23%), Positives = 143/375 (38%), Gaps = 50/375 (13%) Query: 4402 EGPVKPSKPPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460 +G + + PP F + ++P E + + +G+PL + W ++N +K PD Sbjct: 2150 QGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELK--PD---- 2203 Query: 4461 TFSTKSILIIRQVFVEDS--AVFAAVAENRGGTA--KCSANLVVEEKRRQGRGGIV--PP 4514 S LII Q + +S + + NR A KC AN V +V PP Sbjct: 2204 -----SRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQYPP 2258 Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY----- 4569 F + ++ VT V L ++ V WLK+ + + G++ Sbjct: 2259 KFFQSPKDKTVTEKSDVTLTCQLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTS 2318 Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ-TKAANAPPEIIEP 4628 +L I D +Y C AIN+AG DK Q N PP I + Sbjct: 2319 SLTITNLVRTDEARYSCKAINAAG----------------DKTSEQGLLTVNFPPRIFKT 2362 Query: 4629 LKDKIVAEGQAIEFSCKIVGK---PLPTVQWYKGDKLIKPSKYFQMSRTADEY------T 4679 ++ EGQ I F+C + GK P V W K + +++ Y + Sbjct: 2363 SANQTREEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTAS 2422 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739 L I EDEG Y+C A NS V + +T + + + +++ + Sbjct: 2423 LTIKNVQREDEGFYQCFAENSLKTVYSTPSIHLTVHFNS-TIFECSGAQNVTERQNDDVI 2481 Query: 4740 FKTQITSKIKPTIQW 4754 ++ K KP + W Sbjct: 2482 IWCEVEGKPKPEVSW 2496 Score = 67.3 bits (157), Expect = 3e-10 Identities = 56/178 (31%), Positives = 75/178 (42%), Gaps = 12/178 (6%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 VTEG+ C GRP P WF +D + N + ++E GN L+ T ++ D G Sbjct: 965 VTEGQNVTLLCVAEGRPTPSYQWFKDDSPFDAENNTRASLSE-GN--LIFTKISRDDHGQ 1021 Query: 463 VTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521 C+A N S T+ +LNV K P S + EGE V L A G P+P Sbjct: 1022 YYCLANNSVSNVTSSIAQLNVFFK-----PDISTYPSPQTITEGENVTLLCVAEGRPSPS 1076 Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN-VAGSTATRARL 578 W KD P R G L + D Y C A N V+ T++ A+L Sbjct: 1077 YQWFKDDSPFDAKYNTRASLSEG--NLIFTKVSRDDHGQYYCLANNSVSNVTSSIAKL 1132 Score = 67.3 bits (157), Expect = 3e-10 Identities = 82/341 (24%), Positives = 130/341 (38%), Gaps = 39/341 (11%) Query: 271 KPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI----ITTHNHTTLRVR 326 KP ++ E + +L G P V W K+ L ++ I + +TL++ Sbjct: 1818 KPEETR-NETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKII 1876 Query: 327 NTQKSDSGHYTLLAENP-NGCIVTSGYLAVESPTE---SYVQDQRSQYITDTQQRETEER 382 N + D +Y A N N T+ + V+ SY S IT+ R E R Sbjct: 1877 NVNRHDEAYYKCRANNTVNTTASTNTSVVVQITVTHPGSYGNTTSSLTITNLV-RTDEAR 1935 Query: 383 IEI----------SEKALA-----PQFVKVCQDRDV-TEGKMTRFDCRVTGRPYPEVTWF 426 SE+ L P+F++ + + E C++ G+P V W Sbjct: 1936 YSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWL 1995 Query: 427 INDRQIRDDYNHKILVN----ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 ++ +++ D + I+ +SG L I NV D C A N T +V Sbjct: 1996 KDNTELKPD-SRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTSV 2054 Query: 483 IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542 + + PKF + V E V L + P +TW KD P+ +P+ T Sbjct: 2055 VVQ---YPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTH 2111 Query: 543 GGA-----STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 G+ S+L I +D A Y C A N AG ++ L Sbjct: 2112 PGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGL 2152 Score = 66.5 bits (155), Expect = 5e-10 Identities = 72/302 (23%), Positives = 116/302 (38%), Gaps = 41/302 (13%) Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524 S L+I + D A + A+N G S NL V PP F + ++ Sbjct: 1479 SFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVN----------YPPKFLQSLKDEE 1528 Query: 4525 -VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE----EDGTYTLLILEAYPQ 4579 + + L K+ G V WLK+ +++PD R I + + G TL I+ + Sbjct: 1529 TLNETDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRH 1588 Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 D Y+C+A N+ V PP+ + K++ V E Sbjct: 1589 DEAYYKCLANNTVDTTTSTTNTSV--------------VVQYPPKFFQSPKNETVTEKSN 1634 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY-----TLRISEAFPEDEGDYK 4694 + +C++ KP +V W K + + S Y +L I+ DE Y Sbjct: 1635 VTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYS 1694 Query: 4695 CVAYNSAGRVTVA-AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753 C A N+AG T L V P + LTP +++ + EG ++ K + T+ Sbjct: 1695 CKAINAAGEKTSEQGLLTVNYPPKI-----LTPPKNVTITEGNDVTLSCEVEGKPEVTVD 1749 Query: 4754 WL 4755 WL Sbjct: 1750 WL 1751 Score = 64.5 bits (150), Expect = 2e-09 Identities = 75/344 (21%), Positives = 129/344 (37%), Gaps = 45/344 (13%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE----IITTHNH 320 PPKI P+N + EG D ++ G P V W + S+ E +T Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCEVEGKPEVTVDWLNGSTPIELSSVIEKTGLAVTGIGL 1775 Query: 321 TTLRVRNTQKSDSGHYTLLAE-NPNGCIVTSGYLAVESPTESYVQDQRSQ---------- 369 + L ++ + G Y A+ +P+ Y+ V ++ R++ Sbjct: 1776 SNLTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTCKL 1835 Query: 370 ---------YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPY 420 ++ D + + + R+ I++ +L + +V + CR Sbjct: 1836 EGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNT-- 1893 Query: 421 PEVTWFINDRQIRDDYNHKILVNESGNH-----ALMITNVTLSDSGVVTCVARNKSGETA 475 T N + +I V G++ +L ITN+ +D +C A N +GE + Sbjct: 1894 VNTTASTNTSVV-----VQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKS 1948 Query: 476 FQCRLNVIEKEQVVAPKFVERFSTLNVR-EGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534 + L + PKF+E R E + + L + G P + W KD + P+ Sbjct: 1949 SEQGLLTVN----YPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPD 2004 Query: 535 PELRI----HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574 L I D G STL I D A+Y+C A N +T + Sbjct: 2005 SRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANNTVDTTTS 2048 Score = 62.9 bits (146), Expect = 6e-09 Identities = 98/406 (24%), Positives = 156/406 (38%), Gaps = 58/406 (14%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 P I T +V E E G+P+P + W R+ + + + + +T L Sbjct: 1230 PSITTHPQNQTKV-EGEIVTLSCTVTGDPVPTVYWSRDGSNL-TALRYLVEPSNT---LK 1284 Query: 4470 IRQVFVEDSAVFAAVAENR-GGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVT 4526 I + ED + A N T+ +A L V PP F +L + Sbjct: 1285 IENLTREDEGSYICHAFNNVSSTSSDAAVLTVN----------YPPKFLESLKPKETRNE 1334 Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE----EDGTYTLLILEAYPQDSG 4582 + L L K+ G V WLK+ +++PD R I + + G TL I+ D Sbjct: 1335 TDNLT-LTCKLEGKPQATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINLDRSDEA 1393 Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642 Y+C A N+ G +V+ T T PP+ + + I EG ++ Sbjct: 1394 SYKCRANNTVG--------IVTSSNT-------TVTVQYPPKFFKIPDNVIKTEGSSVNL 1438 Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPS----KYFQMSRTADEYT-LRISEAFPEDEGDYKCVA 4697 +C++ KP +V W G L+ S Q +E + L IS DE Y C A Sbjct: 1439 TCQLECKPKCSVTWLIGGSLLDTSSDRISVTQPENDGNETSFLMISNLNRTDEASYTCRA 1498 Query: 4698 YNSAGRVTV-AAKLKVTQPDQADNLPALTPLRD-IVVYEGQPAQFKTQITSKIKPTIQWL 4755 N+AG T + L V P + L L+D + E ++ K T+ WL Sbjct: 1499 KNAAGEKTSGSVNLAVNYPPK-----FLQSLKDEETLNETDNLTLTCKLEGKPLATVVWL 1553 Query: 4756 REGALIPETPDFQMI------HEGNNAVLLIGNTYEEDTGTFTCRA 4795 ++ + PD ++I + + L I N + D + C A Sbjct: 1554 KDNTEL--EPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYKCLA 1597 Score = 61.3 bits (142), Expect = 2e-08 Identities = 52/196 (26%), Positives = 77/196 (39%), Gaps = 13/196 (6%) Query: 392 PQFVKVCQDRDV-TEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL---VNESGN 447 P+F++ + + E C++ G+P V W ++ +++ D I + ESG Sbjct: 2159 PKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGE 2218 Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507 L I NV D C A N TA V++ PKF + V E Sbjct: 2219 STLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQ----YPPKFFQSPKDKTVTEKSD 2274 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA-----STLDIPRAKASDAAWYQ 562 V L + P +TW KD P+ +P T G+ S+L I +D A Y Sbjct: 2275 VTLTCQLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYS 2334 Query: 563 CTAQNVAGSTATRARL 578 C A N AG + L Sbjct: 2335 CKAINAAGDKTSEQGL 2350 Score = 59.3 bits (137), Expect = 8e-08 Identities = 52/184 (28%), Positives = 78/184 (42%), Gaps = 14/184 (7%) Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120 +EGQ+ +E TG+ S + W +G + S R + +L I DSGT Sbjct: 784 TEGQVVKFECQT--TGNPSPNVTWLKSGSAVNTSVDPR--FYSNDTILMITNVSRIDSGT 839 Query: 3121 YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180 YSC A+N+ G L D G P F Q+ + +G S FEC +P Sbjct: 840 YSCNASNELGIISAEAAL---DVRYG--PEFVNVPQD-KTPNEGWSVTFECHTK--GNPP 891 Query: 3181 MKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240 + W NG + S + S+ ++ I DSG Y C A + G T+A+++ Sbjct: 892 PTVTWLKNGSALNTSVDPRFYSNGTHLM--ITNVNRTDSGAYRCNASSILGVITTKASLD 949 Query: 3241 CYGK 3244 Y K Sbjct: 950 VYFK 953 Score = 58.8 bits (136), Expect = 1e-07 Identities = 77/360 (21%), Positives = 133/360 (36%), Gaps = 35/360 (9%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P+ + ++ +TEG C V G+P V W I ++ ++G L Sbjct: 1717 PKILTPPKNVTITEGNDVTLSCEVEGKPEVTVDWLNGSTPIE----LSSVIEKTG---LA 1769 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRL----NVIEKEQV-VAPKFVERFSTLNVR-EG 505 +T + LS+ +T ++ E +++CR + E + + F+ R E Sbjct: 1770 VTGIGLSN---LTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRNET 1826 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH----TDGGASTLDIPRAKASDAAWY 561 + + L + G P + W KD + P+ L I + G STL I D A+Y Sbjct: 1827 DNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYY 1886 Query: 562 QCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXY-LRHVER 620 +C A N +TA+ + + + Y + + Sbjct: 1887 KCRANNTVNTTAS---TNTSVVVQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINA 1943 Query: 621 ARPYIPPGEEDRVYPPPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSI 679 A V PP+F+ LK T E + ++E G P + WLK+ + Sbjct: 1944 AGEKSSEQGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTEL 2001 Query: 680 EASSRF----TSIFRFGYISLDMLSLNIQDSGEYTCRA----VSATGVAETKAVLHVTPR 731 + SR S G +L ++++N D Y CRA + T T V+ P+ Sbjct: 2002 KPDSRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYPPK 2061 Score = 57.2 bits (132), Expect = 3e-07 Identities = 76/326 (23%), Positives = 125/326 (38%), Gaps = 24/326 (7%) Query: 699 LSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQH 758 LS ++ E T ++ + E +V+ T A + T++ + + + S Y+ Sbjct: 1736 LSCEVEGKPEVTVDWLNGSTPIELSSVIEKTGLA-VTGIGLSNLTIKGVSRYYEGS-YKC 1793 Query: 759 QESIEEQTSQRPQFIRPLQDLGEL--QEGRNAHFEAQLTPVSD--PTMRVEWYKDGRPIT 814 + + TS+ + LG L +E RN LT + P V W KD + Sbjct: 1794 RAKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELK 1853 Query: 815 ASSRIT----SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST-ASIRVAARST-- 867 SR+ S+ G +L I+++ D Y RA N + ST S+ V T Sbjct: 1854 PDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQITVTHP 1913 Query: 868 -----VTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIK 922 T+ L I R E + P+F +K + + Sbjct: 1914 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEETRN 1973 Query: 923 EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT----TFFNFGYVALTIKSVTVHD 978 E +LE G V WLKD ++ SR+ + + G LTI +V HD Sbjct: 1974 ETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINVNRHD 2031 Query: 979 AGHYTCRAYNAIGQATTSANLTIVTK 1004 +Y CRA N + T++ N ++V + Sbjct: 2032 EAYYKCRANNTVDTTTSTTNTSVVVQ 2057 Score = 54.8 bits (126), Expect = 2e-06 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+ +P+ EG +F+ Q +GNP P VTW K+G + S + N T L + Sbjct: 772 PQFIVEPKGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVDPRFYS--NDTILMI 829 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 N + DSG Y+ A N G I L V Sbjct: 830 TNVSRIDSGTYSCNASNELGIISAEAALDV 859 Score = 53.6 bits (123), Expect = 4e-06 Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 2/90 (2%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+ P++ EG F+ GNP P VTW KNG L S + N T L + Sbjct: 863 PEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALNTSVDPRFYS--NGTHLMI 920 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 N ++DSG Y A + G I T L V Sbjct: 921 TNVNRTDSGAYRCNASSILGVITTKASLDV 950 Score = 53.6 bits (123), Expect = 4e-06 Identities = 47/190 (24%), Positives = 77/190 (40%), Gaps = 19/190 (10%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH--- 448 P+F + +D+ VTE C++ +P VTW + D D +I V G+ Sbjct: 2258 PKFFQSPKDKTVTEKSDVTLTCQLECKPKCSVTW-LKDNTPLDTSPVRITVTHPGSFGNT 2316 Query: 449 --ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506 +L ITN+ +D +C A N +G+ + L + P+ + + EG+ Sbjct: 2317 TSSLTITNLVRTDEARYSCKAINAAGDKTSEQGLLTVN----FPPRIFKTSANQTREEGQ 2372 Query: 507 PVVLNARAVG---TPTPRITWQKDGVPIIPNPELRIHTDG----GAST--LDIPRAKASD 557 + G T P + W+KDG + + G ST L I + D Sbjct: 2373 QITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQRED 2432 Query: 558 AAWYQCTAQN 567 +YQC A+N Sbjct: 2433 EGFYQCFAEN 2442 Score = 52.4 bits (120), Expect = 9e-06 Identities = 80/359 (22%), Positives = 140/359 (38%), Gaps = 40/359 (11%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 PP+ T P ++ ++E + C + + V+W + P+ S I G + Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCEV--EGKPEVTVDWLNGSTPIELSS---VIEKTGLAV 1770 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676 IG T K +R+ E + C+ + R E P++ K E Sbjct: 1771 TGIG------LSNLTIKGVSRYYEGSYKCRAK---RDPDTSESD-PAYITVNFLGSLKPE 1820 Query: 3677 ETLHKREEITIEDEKPNPPRFTVE-IKDNIDV-PEGGPVHFDCRVEPVGDPTMRIDWFHN 3734 ET ++ + +T+ + P TV +KDN ++ P+ + + G+ T++I + Sbjct: 1821 ETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKI--INV 1878 Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794 R + N A + + T +G+ T++ IT + D Sbjct: 1879 NRHDEAYYKCRANNTVNTTASTNTSVVV----QITVTHPGSYGNTTSSLTITNLVRTDEA 1934 Query: 3795 LESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIK-SHTVEESEGVRFECRV 3853 S +GEK E +G ++ V+ PPKF+ +K T E++ + C++ Sbjct: 1935 RYSCKAINAAGEKSSE--QGLLT--------VNYPPKFLESLKPEETRNETDNLTLTCKL 1984 Query: 3854 EPKEDPKLRIEWYR-NGKLLPSGHRYRTV---YDMGFVSLDILYVYAEDSGEYICRAVN 3908 E K P + W + N +L P T D G +L I+ V D Y CRA N Sbjct: 1985 EGK--PLATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANN 2041 Score = 51.6 bits (118), Expect = 2e-05 Identities = 90/413 (21%), Positives = 143/413 (34%), Gaps = 47/413 (11%) Query: 4368 TQKEVVGDKEITRKITSTET-TEIEHKAQTQERV-----VEGPVKPSKPPIFTKKMQPCR 4421 TQ +V E T KI + E +K + V V PP F + + Sbjct: 2209 TQPSLVESGESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQYPPKFFQSPKDKT 2268 Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-----STKSILIIRQVFVE 4476 V E + + +P + W ++N P+ SP T +T S L I + Sbjct: 2269 VTEKSDVTLTCQLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRT 2328 Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536 D A ++ A N G L+ PP T+ N GQ + Sbjct: 2329 DEARYSCKAINAAGDKTSEQGLLTVN---------FPPRIFKTSANQTREEGQQITFTCD 2379 Query: 4537 VTG---TKPIDVYWLKNGKKVQPDIRNKILEEDGTY------TLLILEAYPQDSGKYECV 4587 V G T P +VYW K+G V D + Y +L I +D G Y+C Sbjct: 2380 VEGKEGTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCF 2439 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647 A NS + V S P+ T N+ ++ + + C++ Sbjct: 2440 AENS-------LKTVYSTPSIH-----LTVHFNSTIFECSGAQNVTERQNDDVIIWCEVE 2487 Query: 4648 GKPLPTVQWY-KG-DKLIKPSKYFQMSRTADEYTLRISEAFPE-DEGDYKCVAYNSAGRV 4704 GKP P V W+ +G + ++P+ + + A+ ++ + + GD R Sbjct: 2488 GKPKPEVSWHVRGRGQQVEPNARITIEQPANTSRQKVRLVIKQVERGDTGMYYIKIGARS 2547 Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757 L V P + NL D V G+ + PT WL++ Sbjct: 2548 YEPRLLNVQYPAENINLKVSD---DGKVDVGKQISLVCEAGGNPIPTFSWLKD 2597 Score = 51.2 bits (117), Expect = 2e-05 Identities = 36/108 (33%), Positives = 51/108 (47%), Gaps = 5/108 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F+ + T EG + FE + G+P + WLKNG ++ S F L Sbjct: 863 PEFVNVPQDKTPNEGWSVTFECHTK--GNPPPTVTWLKNGSALNTS--VDPRFYSNGTHL 918 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744 + ++N DSG Y C A S GV TKA L V + I T P+T+ Sbjct: 919 MITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDIS-THPSPQTV 965 Score = 50.8 bits (116), Expect = 3e-05 Identities = 111/497 (22%), Positives = 174/497 (35%), Gaps = 56/497 (11%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL-VECNKYSMRYNEQTGDV 129 PP F Q KN + N +L P V+W + PL ++ ++ + G+ Sbjct: 2059 PPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNT 2118 Query: 130 --SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE--T 185 SL I + DE Y+C A N GE + R+ ++ T Sbjct: 2119 TSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEETRNETDNLT 2178 Query: 186 VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL-LREVSFRESITKRY 244 + K G T + ++ + T V++ E L + V+ + + Sbjct: 2179 LTCKLEGKPLATVVWLKDNTELKPDSRL--IITQPSLVESGESTLKIINVNRHDEAYYKC 2236 Query: 245 VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304 + V + + S+ PPK Q P++ + E +D QL P+ VTW K+ Sbjct: 2237 RANNTVNTTASTNTSVVVQYPPKFFQSPKDKTVTEKSDVTLTCQLECKPKCSVTWLKDNT 2296 Query: 305 RLINSNKHEIITTH----NHTT--LRVRNTQKSDSGHYTLLAENPNGCIVT-SGYLAVES 357 L +++ I TH +TT L + N ++D Y+ A N G + G L V Sbjct: 2297 PL-DTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQGLLTVNF 2355 Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417 P I T +T E Q C DV EGK G Sbjct: 2356 PPR----------IFKTSANQTREE--------GQQITFTC---DV-EGK--------EG 2385 Query: 418 RPYPEVTWFINDRQIRDDYNHKIL---VNESG--NHALMITNVTLSDSGVVTCVARN--K 470 P V W + + D N N G +L I NV D G C A N K Sbjct: 2386 TSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSLK 2445 Query: 471 SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530 + + L V + + + R+ + V++ G P P ++W G Sbjct: 2446 TVYSTPSIHLTVHFNSTIFECSGAQ---NVTERQNDDVIIWCEVEGKPKPEVSWHVRGRG 2502 Query: 531 IIPNPELRIHTDGGAST 547 P RI + A+T Sbjct: 2503 QQVEPNARITIEQPANT 2519 Score = 50.4 bits (115), Expect = 3e-05 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 11/108 (10%) Query: 628 GEEDRVYP-------PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIE 680 G D+ YP PQFIV K T EG + FE + G+P+ + WLK+G ++ Sbjct: 756 GRTDKSYPGTLIVKYAPQFIVEPKGKTTTEGQVVKFEC--QTTGNPSPNVTWLKSGSAVN 813 Query: 681 ASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 S F L + +++ DSG Y+C A + G+ +A L V Sbjct: 814 TS--VDPRFYSNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDV 859 Score = 50.4 bits (115), Expect = 3e-05 Identities = 70/301 (23%), Positives = 113/301 (37%), Gaps = 15/301 (4%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL-VECNKYSMRYNEQTGDV 129 PP F +I N +G + +L P V+W + L ++ S+ E G+ Sbjct: 1418 PPKFFKIPDNVIKTEGSSVNLTCQLECKPKCSVTWLIGGSLLDTSSDRISVTQPENDGNE 1477 Query: 130 S--LLIKQIGPGDEGEYTCTARNQYGEAIC-SVYIQPEGXXXXXXXXXXXXXYRHVSE-T 185 + L+I + DE YTC A+N GE SV + T Sbjct: 1478 TSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEETLNETDNLT 1537 Query: 186 VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL-LREVSFRESITKRY 244 + K G T + ++ + T VD+ E L + V + + Sbjct: 1538 LTCKLEGKPLATVVWLKDNTELEPDSRL--IITQPSSVDSGESTLTIINVHRHDEAYYKC 1595 Query: 245 VGESDVQISTEIDRSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303 + + V +T + V PPK Q P+N + E ++ QL P+ VTW K+ Sbjct: 1596 LANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDN 1655 Query: 304 QRLINSNKHEIIT---THNHTT--LRVRNTQKSDSGHYTLLAENPNGCIVT-SGYLAVES 357 L S +T ++ +TT L + N ++D Y+ A N G + G L V Sbjct: 1656 TPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVNY 1715 Query: 358 P 358 P Sbjct: 1716 P 1716 Score = 49.6 bits (113), Expect = 6e-05 Identities = 38/115 (33%), Positives = 53/115 (46%), Gaps = 7/115 (6%) Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT-SND 1898 V AP+FI + G T +EGQ +EC+ P PN V W +G + + R SND Sbjct: 768 VKYAPQFIVEPKGKTT-TEGQVVKFECQTTGNPSPN--VTWLKSGSAVNTSVDPRFYSND 824 Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953 L I V DSG Y+C A N LG + L+V+ + Q ++ E Sbjct: 825 ---TILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQDKTPNE 876 Score = 49.2 bits (112), Expect = 8e-05 Identities = 57/240 (23%), Positives = 97/240 (40%), Gaps = 25/240 (10%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLT----TMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793 G P V WL++ ++ +RL ++ + G L + VN D Y CRA N + Sbjct: 1837 GKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVNT 1896 Query: 1794 -AVTSSTLFVQSKASLQLESQHESALQKIQQL--EDSSRYQRR----------EDVEVAV 1840 A T++++ VQ + + ++ I L D +RY + E + V Sbjct: 1897 TASTNTSVVVQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTV 1956 Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR----YRTS 1896 N P+F+ L +E + C++E P V W + L+ R +S Sbjct: 1957 NYPPKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSS 2014 Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLN--VQSKESIIRDSQHESALEK 1954 D G + L I+ V D Y C+A N + S+ + VQ + ++E+ EK Sbjct: 2015 VDSGESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEK 2074 Score = 48.4 bits (110), Expect = 1e-04 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 6/100 (6%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT----TFFNF 964 P+F +KD+ ++ E +LE G V WLKD +E SR+ + + Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLIITQPSSVDS 1575 Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 G LTI +V HD +Y C A N + T++ N ++V + Sbjct: 1576 GESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQ 1615 Score = 48.0 bits (109), Expect = 2e-04 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 10/156 (6%) Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135 G + + W N + + S R + + LEI G D G+Y C +N G+ + S Sbjct: 704 GTEPFNVIWLKNNEVYDFSSDSRVHESHNNLTLEIFGVLPNDHGSYQCDVSN--GRTDKS 761 Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195 + K P+F + + +GQ FEC +P + W +G + S Sbjct: 762 YPGTLIVK---YAPQFIVEPKG-KTTTEGQVVKFECQT--TGNPSPNVTWLKSGSAVNTS 815 Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 + S+ +L I DSG Y C A N+ G Sbjct: 816 VDPRFYSN--DTILMITNVSRIDSGTYSCNASNELG 849 Score = 48.0 bits (109), Expect = 2e-04 Identities = 34/107 (31%), Positives = 46/107 (42%), Gaps = 4/107 (3%) Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355 R K + V APQF T EG V EC Q G+ + V W +G + T Sbjct: 757 RTDKSYPGTLIVKYAPQFIVEPKGKTTTEGQVVKFEC--QTTGNPSPNVTWLKSGSAVNT 814 Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 P + + L + +V DSG Y+C A+N+LG AL V Sbjct: 815 S--VDPRFYSNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDV 859 Score = 48.0 bits (109), Expect = 2e-04 Identities = 46/195 (23%), Positives = 74/195 (37%), Gaps = 15/195 (7%) Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119 ++EG+ + S G + +WF + +A + R + G ++ + D G Sbjct: 1149 VTEGE--NVTLSCAAEGRPTPSYQWFKDDSPFDAGNNARASLSEGNLIFTKVSRD--DHG 1204 Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179 Y C A N S V + P TTH QN + +G+ CTV DP Sbjct: 1205 QYYCLANNSVSNVTSSK----VQLTVFFAPSITTHPQN-QTKVEGEIVTLSCTVT--GDP 1257 Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239 + W +G + + S+ L I D G Y+C A+N + A + Sbjct: 1258 VPTVYWSRDGSNLTALRYLVEPSN----TLKIENLTREDEGSYICHAFNNVSSTSSDAAV 1313 Query: 3240 NCYGKGGVYLESLQP 3254 +LESL+P Sbjct: 1314 LTVNYPPKFLESLKP 1328 Score = 48.0 bits (109), Expect = 2e-04 Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 7/115 (6%) Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV--- 3881 +V PPKF K+ TV E V C++E K PK + W ++ L + TV Sbjct: 2055 VVQYPPKFFQSPKNETVTEKSNVTLTCQLECK--PKCSVTWLKDNTPLDTSPDRITVTHP 2112 Query: 3882 --YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVP 3934 Y SL I + D Y C+A+N GE ++ + P L++ P Sbjct: 2113 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKP 2167 Score = 47.2 bits (107), Expect = 3e-04 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 7/110 (6%) Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV--- 3881 +V PPKF K+ TV E V C++E K PK + W ++ L + TV Sbjct: 1613 VVQYPPKFFQSPKNETVTEKSNVTLTCQLECK--PKCSVTWLKDNTPLDTSPDRITVTHP 1670 Query: 3882 --YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929 Y SL I + D Y C+A+N GE ++ + P IL Sbjct: 1671 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVNYPPKIL 1720 Score = 46.8 bits (106), Expect = 4e-04 Identities = 34/123 (27%), Positives = 51/123 (41%), Gaps = 12/123 (9%) Query: 3810 ELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869 ++ GR + IV P+FI + K T E + V+FEC+ P + W Sbjct: 752 DVSNGRTDKSYPGTLIVKYAPQFIVEPKGKTTTEGQVVKFECQTTGNPSP--NVTW---- 805 Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAE----DSGEYICRAVNDFGEDFTKATISCKKLP 3925 L SG T D F S D + + DSG Y C A N+ G +A + + P Sbjct: 806 --LKSGSAVNTSVDPRFYSNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGP 863 Query: 3926 DII 3928 + + Sbjct: 864 EFV 866 Score = 46.8 bits (106), Expect = 4e-04 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 7/112 (6%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 + V P+F + EG +V EC + G+ V W NG + T P + Sbjct: 857 LDVRYGPEFVNVPQDKTPNEGWSVTFECHTK--GNPPPTVTWLKNGSALNTS--VDPRFY 912 Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416 + L + +V DSG Y C A++ LG T +L V K D+ S HPS Sbjct: 913 SNGTHLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI---STHPS 961 Score = 46.0 bits (104), Expect = 8e-04 Identities = 80/353 (22%), Positives = 130/353 (36%), Gaps = 48/353 (13%) Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRF----KTYYDFGFVALDIIHATSA 1245 +E N+ L C+LE G P V W + + SR + + G L II+ Sbjct: 1824 NETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRH 1881 Query: 1246 DTGEYTVRA---VNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQLLEDAARRTKQV 1301 D Y RA VN S +TS +V++ + +T + I + RT + Sbjct: 1882 DEAYYKCRANNTVNTTASTNTSVVVQITVTHPGSYGNTTSSLTITNLV-------RTDEA 1934 Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLEC-RLQPVGDQTMRVEWFCN--GKPIKTGHR 1358 R + A + + TV LE + + ++T + C GKP+ T Sbjct: 1935 RYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVW 1994 Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418 + D + P+ + T ++ GE+ + +I ++H Sbjct: 1995 LK----------DNTELKPDSRLIITQPSSVDSGESTLT----------IINVNRHDEAY 2034 Query: 1419 EKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKV 1478 K + T V P+F PK+ E V E +V C+LE V Sbjct: 2035 YKCRANNTVDTTTSTTNTSVVVQYPPKFFQSPKN-ETVTEKSNVTLTCQLE--CKPKCSV 2091 Query: 1479 EWFKNGQPV-TIGHRFRPIHDFGY----VALDIIDLIAEDSGIYTCRAVNLVG 1526 W K+ P+ T R H Y +L I +L+ D Y+C+A+N G Sbjct: 2092 TWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAG 2144 Score = 45.6 bits (103), Expect = 0.001 Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 7/125 (5%) Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884 +V PPKF K TV E V C++E K PK + W ++ L + TV Sbjct: 2253 VVQYPPKFFQSPKDKTVTEKSDVTLTCQLECK--PKCSVTWLKDNTPLDTSPVRITVTHP 2310 Query: 3885 GFV-----SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939 G SL I + D Y C+A+N G+ ++ + P I + + + Sbjct: 2311 GSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQGLLTVNFPPRIFKTSANQTREE 2370 Query: 3940 SEALT 3944 + +T Sbjct: 2371 GQQIT 2375 Score = 45.2 bits (102), Expect = 0.001 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 4/98 (4%) Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765 ++ AP F + K E Q FE + G+P V WL++G + S + Sbjct: 767 IVKYAPQFIVEPKGKTTTEGQVVKFECQT--TGNPSPNVTWLKSGSAVNTS--VDPRFYS 822 Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 L + V+ DSGTY+C A NELG + L V+ Sbjct: 823 NDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVR 860 Score = 45.2 bits (102), Expect = 0.001 Identities = 38/112 (33%), Positives = 51/112 (45%), Gaps = 14/112 (12%) Query: 903 PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962 PE P+ KTP EG FE + G+ V WLK+G + S F+ Sbjct: 863 PEFVNVPQDKTP-------NEGWSVTFECHTK--GNPPPTVTWLKNGSALNTSVD-PRFY 912 Query: 963 NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014 + G L I +V D+G Y C A + +G TT A+L + K DI S HP Sbjct: 913 SNG-THLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI---STHP 960 Score = 44.4 bits (100), Expect = 0.002 Identities = 56/272 (20%), Positives = 90/272 (33%), Gaps = 14/272 (5%) Query: 79 KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138 K +G KFE + GNP+P V+W + + + S+ + D L+I + Sbjct: 779 KGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAV----NTSVDPRFYSNDTILMITNVSR 834 Query: 139 GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198 D G Y+C A N+ G + S T E G T Sbjct: 835 IDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQDKTPNEGWSVTFECHTKGNPPPTV 894 Query: 199 EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDR 258 + + ++S D + ++ V+ +S R S + + T Sbjct: 895 TWLKNGSAL-------NTSVDPRFYSNGTHLMITNVNRTDSGAYRCNASSILGVIT-TKA 946 Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318 SL P I+ P + EG + G P P WFK+ N + Sbjct: 947 SLDVYFKPDISTHPSPQTVTEGQNVTLLCVAEGRPTPSYQWFKDDSPFDAENNTRASLSE 1006 Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 + L + D G Y LA N + +S Sbjct: 1007 GN--LIFTKISRDDHGQYYCLANNSVSNVTSS 1036 Score = 44.4 bits (100), Expect = 0.002 Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 4/98 (4%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P+F+ + T E V FEC K +P + W +NG L + R Y G L Sbjct: 863 PEFVNVPQDKTPNEGWSVTFECHT--KGNPPPTVTWLKNGSALNTSVDPR-FYSNG-THL 918 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927 I V DSG Y C A + G TKA++ PDI Sbjct: 919 MITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956 Score = 44.4 bits (100), Expect = 0.002 Identities = 54/260 (20%), Positives = 91/260 (35%), Gaps = 18/260 (6%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G N G P+P W + +P KY+ R + G+ L+ ++ D G+Y Sbjct: 1059 EGENVTLLCVAEGRPSPSYQWFKDDSPFDA--KYNTRASLSEGN--LIFTKVSRDDHGQY 1114 Query: 145 TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVS-ETVEHKAYGTQGYTTEQSRQ 203 C A N S+ H S +TV T E Sbjct: 1115 YCLANNSVSNVTSSI--------AKLTVFFKPDISTHPSPQTVTEGENVTLSCAAEGRPT 1166 Query: 204 TQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRY-VGESDVQISTEIDRSLGP 262 + + + + ++ + E L+ R+ + Y + + V T L Sbjct: 1167 PSYQWFKDDSPFDAGNNARASLSEGNLIFTKVSRDDHGQYYCLANNSVSNVTSSKVQLTV 1226 Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 P I P+N EG ++G+P P V W ++G L + ++ N T Sbjct: 1227 FFAPSITTHPQNQTKVEGEIVTLSCTVTGDPVPTVYWSRDGSNL--TALRYLVEPSN--T 1282 Query: 323 LRVRNTQKSDSGHYTLLAEN 342 L++ N + D G Y A N Sbjct: 1283 LKIENLTREDEGSYICHAFN 1302 Score = 43.2 bits (97), Expect = 0.005 Identities = 41/169 (24%), Positives = 58/169 (34%), Gaps = 14/169 (8%) Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458 Q + V G F C T P + W +D N I S L + NV Sbjct: 601 QPKSVFTGDDVTFTCNATALAAPSIWWQ------KDGVNITI----SDGSTLNLVNVKEG 650 Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518 DSG TCVA T ++ + P + + E V + A GT Sbjct: 651 DSGNYTCVAEAGENTTTSDAAFLSVK----LPPVITNHPANQTANKDENVTIACSANGTE 706 Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 + W K+ + + R+H TL+I +D YQC N Sbjct: 707 PFNVIWLKNNEVYDFSSDSRVHESHNNLTLEIFGVLPNDHGSYQCDVSN 755 Score = 43.2 bits (97), Expect = 0.005 Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 5/110 (4%) Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499 V P+F+ PK + EGQ V FEC+ N V W K+G V P Sbjct: 768 VKYAPQFIVEPKG-KTTTEGQVVKFECQTTGNPSPN--VTWLKSGSAVNTS--VDPRFYS 822 Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE 1549 L I ++ DSG Y+C A N +G L R + V Q++ Sbjct: 823 NDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQDK 872 Score = 43.2 bits (97), Expect = 0.005 Identities = 41/142 (28%), Positives = 60/142 (42%), Gaps = 7/142 (4%) Query: 2606 IIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQ 2665 I + R + + L +++ V V V AP TTH ++ K VEG+ V L Sbjct: 1194 IFTKVSRDDHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTK-VEGEIVTLSCT 1252 Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725 V DP + W ++G LT L + TL I +L +D G Y C A N + Sbjct: 1253 VTG--DPVPTVYWSRDGSNLTALRYLVEPSN----TLKIENLTREDEGSYICHAFNNVSS 1306 Query: 2726 AVSTASIKIEDRHWLLGESLHP 2747 S A++ + ESL P Sbjct: 1307 TSSDAAVLTVNYPPKFLESLKP 1328 Score = 43.2 bits (97), Expect = 0.005 Identities = 56/237 (23%), Positives = 95/237 (40%), Gaps = 19/237 (8%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF----TSIFRF 691 PP+ + P K+VT EG + +E G P + ++WL IE SS ++ Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCEVE--GKPEVTVDWLNGSTPIELSSVIEKTGLAVTGI 1773 Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAET-KAVLHVTPRATI--ERTSQHPETLQYIQ 748 G +L + ++ G Y CRA +E+ A + V ++ E T + L Sbjct: 1774 GLSNLTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTC 1833 Query: 749 QLED---YSKYQHQESIEEQTSQRPQFIRP-LQDLGELQ---EGRNAHFEAQLTPVSDPT 801 +LE + +++ E + R +P L + GE N H EA ++ T Sbjct: 1834 KLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNT 1893 Query: 802 MRVEWYKDGRPITASSRITSIFNFGYV--SLNIMHLRAEDAGSYTVRAVNKLGEAIS 856 + + +T ++G SL I +L D Y+ +A+N GE S Sbjct: 1894 VNTT-ASTNTSVVVQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSS 1949 Score = 42.7 bits (96), Expect = 0.007 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 1/71 (1%) Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF 4167 R P FV++P T EG F C G+P P V WL NG+ + N S Y H Sbjct: 860 RYGPEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSAL-NTSVDPRFYSNGTHL 918 Query: 4168 DIPKTRQYDTG 4178 I + D+G Sbjct: 919 MITNVNRTDSG 929 Score = 42.7 bits (96), Expect = 0.007 Identities = 56/285 (19%), Positives = 97/285 (34%), Gaps = 25/285 (8%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P F + ++ +G + FE +GNP P V+W + + L S+ + L Sbjct: 863 PEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSAL----NTSVDPRFYSNGTHL 918 Query: 132 LIKQIGPGDEGEYTCTARNQYG----EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVE 187 +I + D G Y C A + G +A VY +P+ H S Sbjct: 919 MITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPD-------------ISTHPSPQTV 965 Query: 188 HKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRY-V 245 + + R T + + + + ++ + E L+ R+ + Y + Sbjct: 966 TEGQNVTLLCVAEGRPTPSYQWFKDDSPFDAENNTRASLSEGNLIFTKISRDDHGQYYCL 1025 Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 + V T L P I+ P + EG + G P P WFK+ Sbjct: 1026 ANNSVSNVTSSIAQLNVFFKPDISTYPSPQTITEGENVTLLCVAEGRPSPSYQWFKDDSP 1085 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 K+ + + L + D G Y LA N + +S Sbjct: 1086 F--DAKYNTRASLSEGNLIFTKVSRDDHGQYYCLANNSVSNVTSS 1128 Score = 42.7 bits (96), Expect = 0.007 Identities = 53/232 (22%), Positives = 87/232 (37%), Gaps = 41/232 (17%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F+Q L + ++E N+ L C+LE G P V W + + SR Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSR----------- 1564 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296 L I +S D+GE T+ +N H A + + + + T T Sbjct: 1565 LIITQPSSVDSGESTLTIIN--VHRHDEAYYKCLANNTVDTTTST--------------- 1607 Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356 + V P+F ++ N E +NV L C+L+ V W + P+ T Sbjct: 1608 ----TNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLE--CKPKCSVTWLKDNTPLDTS 1661 Query: 1357 -HRFRPAYEFDY----VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 R + Y +L + ++ D Y+C+A N GE + L + Sbjct: 1662 PDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTV 1713 Score = 42.3 bits (95), Expect = 0.009 Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 8/125 (6%) Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR--- 1892 V +AVN P+F+ L L+E + C++E P V W + L+ R Sbjct: 1510 VNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLII 1567 Query: 1893 -YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLN--VQSKESIIRDSQHE 1949 +S D G + L I+ V+ D Y C A N + S+ + VQ + ++E Sbjct: 1568 TQPSSVDSGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQYPPKFFQSPKNE 1627 Query: 1950 SALEK 1954 + EK Sbjct: 1628 TVTEK 1632 Score = 42.3 bits (95), Expect = 0.009 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 6/84 (7%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH----DF 2431 P F Q L++ + + E C+L G P V W ++ +E SR+ T D Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKL--EGKPLATVVWLKDNTELEPDSRLIITQPSSVDS 1575 Query: 2432 GYVSMTISHVRDEDEGVYMCRASN 2455 G ++TI +V DE Y C A+N Sbjct: 1576 GESTLTIINVHRHDEAYYKCLANN 1599 Score = 42.3 bits (95), Expect = 0.009 Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 D V G+ I C+ G P+PT W K D+ + S TLR + F Sbjct: 2569 DGKVDVGKQISLVCEAGGNPIPTFSWLKDDENFRIDIVATKSDDKRNMTLREVQRF--YG 2626 Query: 4691 GDYKCVAYNSAGR-----VTVAAKLK 4711 GDY CVA N G+ VTVA ++K Sbjct: 2627 GDYTCVARNGIGQEQKKTVTVAVEVK 2652 Score = 41.9 bits (94), Expect = 0.012 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 V+ AP F K EGQ V E Q PN + W K+G + T + F Sbjct: 768 VKYAPQFIVEPKG-KTTTEGQVVKFECQTTGNPSPN--VTWLKSGSAVNTS--VDPRFYS 822 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L I ++ DSG Y+C A+N LG + A++ + Sbjct: 823 NDTILMITNVSRIDSGTYSCNASNELGIISAEAALDV 859 Score = 41.9 bits (94), Expect = 0.012 Identities = 16/41 (39%), Positives = 24/41 (58%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 P F+ P T EG+ +F C+ TG+P P V WL +G+ + Sbjct: 772 PQFIVEPKGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAV 812 Score = 41.9 bits (94), Expect = 0.012 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 12/102 (11%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG+N+ C E PT +WF ++ P +G +++ S +L T +D G Y Sbjct: 1151 EGENVTLSCAAEGR--PTPSYQWFKDDSPFDAGNNARAS--LSEGNLIFTKVSRDDHGQY 1206 Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFD---TQHPQGKAGLE 2885 C A NS S TS ++ T ++F T HPQ + +E Sbjct: 1207 YCLANNSV-SNVTSSKVQLT----VFFAPSITTHPQNQTKVE 1243 Score = 41.9 bits (94), Expect = 0.012 Identities = 47/157 (29%), Positives = 69/157 (43%), Gaps = 21/157 (13%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS-RVKTI---NDF 3612 PP+F P ++I +E SS + C+L S V W G L T S R+ ND Sbjct: 1418 PPKFFKIPDNVIKTEGSSVNLTCQLECKPKCS--VTWLIGGSLLDTSSDRISVTQPENDG 1475 Query: 3613 GFV-ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES 3671 L I + + D YTC+A N GE T + L P F +S Sbjct: 1476 NETSFLMISNLNRTDEASYTCRAKNAAGEKTSG---------SVNLAVNYPPKF---LQS 1523 Query: 3672 IQKLEETLHKREEITIEDEKPNPPRFTVE-IKDNIDV 3707 + K EETL++ + +T+ + P TV +KDN ++ Sbjct: 1524 L-KDEETLNETDNLTLTCKLEGKPLATVVWLKDNTEL 1559 Score = 41.9 bits (94), Expect = 0.012 Identities = 58/244 (23%), Positives = 91/244 (37%), Gaps = 41/244 (16%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F++ L +E N+ L C+LE G P V W + + SR Sbjct: 1960 PKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSR----------- 2006 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296 L I +S D+GE T+ +N + H A + R++ DT Sbjct: 2007 LIITQPSSVDSGESTLTIINV--NRHDEAYYKC--RANNTVDTT---------------- 2046 Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356 T + V P+F ++ N E +NV L C+L+ V W + P+ T Sbjct: 2047 -TSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLE--CKPKCSVTWLKDNTPLDTS 2103 Query: 1357 -HRFRPAYEFDY----VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILE 1411 R + Y +L + ++ D Y+C+A N GE + L + LE Sbjct: 2104 PDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLE 2163 Query: 1412 SQHP 1415 S P Sbjct: 2164 SLKP 2167 Score = 41.5 bits (93), Expect = 0.016 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 10/101 (9%) Query: 1433 TDIIDESVTIK--PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-TI 1489 T + SV ++ P+F PK+ E V E +V C+LE V W K+ P+ T Sbjct: 1605 TSTTNTSVVVQYPPKFFQSPKN-ETVTEKSNVTLTCQLE--CKPKCSVTWLKDNTPLDTS 1661 Query: 1490 GHRFRPIHDFGY----VALDIIDLIAEDSGIYTCRAVNLVG 1526 R H Y +L I +L+ D Y+C+A+N G Sbjct: 1662 PDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAG 1702 Score = 41.5 bits (93), Expect = 0.016 Identities = 53/199 (26%), Positives = 85/199 (42%), Gaps = 26/199 (13%) Query: 3542 SGTVDTLTPEAESG----NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597 + TVDT T + PP+F +P + ++E S+ C+L S V W + Sbjct: 2040 NNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCS--VTWLKDN 2097 Query: 3598 KPLLTGSRVKTINDFGFV-----ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 PL T T+ G L I + + D Y+CKA N GE + Sbjct: 2098 TPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKS--------SE 2149 Query: 3653 QGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVE-IKDNIDV-PEG 3710 QG +L P F ES+ K EET ++ + +T+ + P TV +KDN ++ P+ Sbjct: 2150 QG-LLTVNYPPKF---LESL-KPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDS 2204 Query: 3711 GPVHFDCRVEPVGDPTMRI 3729 + + G+ T++I Sbjct: 2205 RLIITQPSLVESGESTLKI 2223 Score = 41.5 bits (93), Expect = 0.016 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 13/121 (10%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-----LMITNVTLSDSGVVTCVA 467 C V G+P PEV+W + R + + N +I + + N + L+I V D+G+ Sbjct: 2484 CEVEGKPKPEVSWHVRGRGQQVEPNARITIEQPANTSRQKVRLVIKQVERGDTGMYYI-- 2541 Query: 468 RNKSGETAFQCR-LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526 K G +++ R LNV + + K V ++V G+ + L A G P P +W K Sbjct: 2542 --KIGARSYEPRLLNVQYPAENINLK-VSDDGKVDV--GKQISLVCEAGGNPIPTFSWLK 2596 Query: 527 D 527 D Sbjct: 2597 D 2597 Score = 41.1 bits (92), Expect = 0.021 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 5/102 (4%) Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912 P ++EG++ C E P P+ +W+ + +G+ R S G L V + Sbjct: 1146 PQTVTEGENVTLSCAAEGRPTPSY--QWFKDDSPFDAGNNARASLSEG--NLIFTKVSRD 1201 Query: 1913 DSGEYTCKAINNLGQAVSS-IRLNVQSKESIIRDSQHESALE 1953 D G+Y C A N++ SS ++L V SI Q+++ +E Sbjct: 1202 DHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTKVE 1243 Score = 41.1 bits (92), Expect = 0.021 Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 9/131 (6%) Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746 R N DT+ +++ V+ P F K+ V E +L PK V W Sbjct: 2038 RANNTVDTTTSTTNTSV--VVQYPPKFFQSPKNETVTEKSNVTLTCQL--ECKPKCSVTW 2093 Query: 1747 LRNGVPIEAS-NRLTTMH--DFGYVALNMKYVN--PEDSGTYTCRAINELGEAVTSSTLF 1801 L++ P++ S +R+T H +G ++ N D Y+C+AIN GE + L Sbjct: 2094 LKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLL 2153 Query: 1802 VQSKASLQLES 1812 + LES Sbjct: 2154 TVNYPPKFLES 2164 Score = 41.1 bits (92), Expect = 0.021 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 10/104 (9%) Query: 636 PPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF----TSIFR 690 PP+F+ LK T E + ++E G P + WLK+ ++ SR S+ Sbjct: 2158 PPKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSLVE 2215 Query: 691 FGYISLDMLSLNIQDSGEYTCRA---VSATGVAETKAVLHVTPR 731 G +L ++++N D Y CRA V+ T T V+ P+ Sbjct: 2216 SGESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQYPPK 2259 Score = 40.7 bits (91), Expect = 0.028 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 7/100 (7%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT----TFFNF 964 P+F +K + + E +LE G V WLKD ++ SR+ + Sbjct: 2159 PKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSLVES 2216 Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 G L I +V HD +Y CRA N + T S N ++V + Sbjct: 2217 GESTLKIINVNRHDEAYYKCRANNTV-NTTASTNTSVVVQ 2255 Score = 40.7 bits (91), Expect = 0.028 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 7/100 (7%) Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMH- 1763 V+ P F KD V E +L PK V WL++ P++ S R+T H Sbjct: 2253 VVQYPPKFFQSPKDKTVTEKSDVTLTCQL--ECKPKCSVTWLKDNTPLDTSPVRITVTHP 2310 Query: 1764 -DFGYVALNMKYVN--PEDSGTYTCRAINELGEAVTSSTL 1800 FG ++ N D Y+C+AIN G+ + L Sbjct: 2311 GSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQGL 2350 Score = 40.3 bits (90), Expect = 0.037 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 7/91 (7%) Query: 3826 VSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTV-- 3881 V+ PPKF+ +K T E++ + C++E K P+ + W + N +L P T Sbjct: 1316 VNYPPKFLESLKPKETRNETDNLTLTCKLEGK--PQATVVWLKDNTELKPDSRLIITQPS 1373 Query: 3882 -YDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 D G +L I+ + D Y CRA N G Sbjct: 1374 SVDSGESTLTIINLDRSDEASYKCRANNTVG 1404 Score = 40.3 bits (90), Expect = 0.037 Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 8/126 (6%) Query: 2339 SIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDC 2398 +II+ ++ E K R + + V + P F Q +N + + E C Sbjct: 2023 TIINVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYPPKFFQSPKN-ETVTEKSNVTLTC 2081 Query: 2399 RLIPVGDPTLKVEWFRNEKLIEDS-SRITKTHDFGY----VSMTISHVRDEDEGVYMCRA 2453 +L P V W ++ ++ S RIT TH Y S+TI+++ DE Y C+A Sbjct: 2082 QL--ECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKA 2139 Query: 2454 SNLLGE 2459 N GE Sbjct: 2140 INAAGE 2145 Score = 40.3 bits (90), Expect = 0.037 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 943 VEWLKDGRPVEAS-SRITTFFNFGY----VALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997 V WLKD P++ S RIT Y +LTI ++ D Y+C+A NA G+ ++ Sbjct: 2091 VTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQ 2150 Query: 998 NLTIVTKKDIIAESQHP 1014 L V ES P Sbjct: 2151 GLLTVNYPPKFLESLKP 2167 Score = 39.9 bits (89), Expect = 0.049 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029 K P+F+ + + +T+ E + KFECQ G+P+ V W +G + P + Sbjct: 769 KYAPQFIVEPKGKTT-TEGQVVKFECQTT--GNPSPNVTWLKSGSAV--NTSVDPRFYSN 823 Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072 + V DSG Y C A+N G+ +A + P V Sbjct: 824 DTILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFV 866 Score = 39.9 bits (89), Expect = 0.049 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 1185 NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244 +P V+EG+N+ L C E G PT +WF + G+ + G L + Sbjct: 1145 SPQTVTEGENVTLSCAAE--GRPTPSYQWFKDDSPFDAGNNARASLSEG--NLIFTKVSR 1200 Query: 1245 ADTGEYTVRAVNHLGSAHTSAI-VRVIERSDIVTDTQNEQAIE 1286 D G+Y A N + + +S + + V I T QN+ +E Sbjct: 1201 DDHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTKVE 1243 Score = 39.9 bits (89), Expect = 0.049 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 7/100 (7%) Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS-NRLTTMH- 1763 V+ P F K+ V E +L PK V WL++ P++ S +R+T H Sbjct: 1613 VVQYPPKFFQSPKNETVTEKSNVTLTCQL--ECKPKCSVTWLKDNTPLDTSPDRITVTHP 1670 Query: 1764 -DFGYVALNMKYVN--PEDSGTYTCRAINELGEAVTSSTL 1800 +G ++ N D Y+C+AIN GE + L Sbjct: 1671 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGL 1710 Score = 39.9 bits (89), Expect = 0.049 Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 5/65 (7%) Query: 943 VEWLKDGRPVEAS-SRITTFFNFGY----VALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997 V WLKD P++ S RIT Y +LTI ++ D Y+C+A NA G+ T+ Sbjct: 1649 VTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQ 1708 Query: 998 NLTIV 1002 L V Sbjct: 1709 GLLTV 1713 Score = 39.5 bits (88), Expect = 0.065 Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 5/105 (4%) Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026 +D + P FV Q +T T FEC G+P V W NG L P + Sbjct: 857 LDVRYGPEFVNVPQDKTPNEGWSVT-FECHTK--GNPPPTVTWLKNGSAL--NTSVDPRF 911 Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071 + V DSG Y C A+++ G+ TKA + KP I Sbjct: 912 YSNGTHLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956 Score = 39.5 bits (88), Expect = 0.065 Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 4/102 (3%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 PEF P D +E S FEC + V W NG L T + ++ ++ Sbjct: 863 PEFVNVPQDKTPNEGWSVTFECHT--KGNPPPTVTWLKNGSALNTSVDPRFYSNGTHLM- 919 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659 I V + D+G Y C A++ G T L V + I P Sbjct: 920 -ITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDISTHP 960 Score = 39.5 bits (88), Expect = 0.065 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 4/79 (5%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 EG V E + P + W KNG L T + F L I ++ DSG Y Sbjct: 876 EGWSVTFECHTKGNPPPT--VTWLKNGSALNTS--VDPRFYSNGTHLMITNVNRTDSGAY 931 Query: 2716 TCKATNLLGEAVSTASIKI 2734 C A+++LG + AS+ + Sbjct: 932 RCNASSILGVITTKASLDV 950 Score = 39.5 bits (88), Expect = 0.065 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 11/123 (8%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I TD YSC+A N G+ L V+ P+ T +N+ + +G Sbjct: 1680 LTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVN----YPPKILTPPKNVT-ITEGNDV 1734 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK----TVSDFGFVVLDIAYTQNHDSGEYV 3223 C V P++ ++W + P+ S+ I+ V+ G L I + G Y Sbjct: 1735 TLSCEV--EGKPEVTVDWLNGSTPIELSSVIEKTGLAVTGIGLSNLTIKGVSRYYEGSYK 1792 Query: 3224 CRA 3226 CRA Sbjct: 1793 CRA 1795 Score = 39.5 bits (88), Expect = 0.065 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query: 943 VEWLKDGRPVEASS-RITTFF--NFGYV--ALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997 V WLKD P++ S RIT +FG +LTI ++ D Y+C+A NA G T+ Sbjct: 2289 VTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQ 2348 Query: 998 NLTIV 1002 L V Sbjct: 2349 GLLTV 2353 Score = 39.1 bits (87), Expect = 0.086 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P+F P +E FEC+ + S V W +G + T + ++ IL Sbjct: 772 PQFIVEPKGKTTTEGQVVKFECQT--TGNPSPNVTWLKSGSAVNTSVDPRFYSND--TIL 827 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660 I V + D+G Y+C A+N G + L V+ + PQ Sbjct: 828 MITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQ 870 Score = 39.1 bits (87), Expect = 0.086 Identities = 32/103 (31%), Positives = 42/103 (40%), Gaps = 5/103 (4%) Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899 V P F+ T +EG S +EC + P P V W NG L + R ++ Sbjct: 859 VRYGPEFVNVPQDKTP-NEGWSVTFECHTKGNPPPT--VTWLKNGSALNTSVDPRFYSNG 915 Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942 L I V DSG Y C A + LG + L+V K I Sbjct: 916 --THLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956 Score = 39.1 bits (87), Expect = 0.086 Identities = 30/124 (24%), Positives = 49/124 (39%), Gaps = 5/124 (4%) Query: 2606 IIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQ 2665 I + R + + L +++ V V P +TH S + EG++V L Sbjct: 1102 IFTKVSRDDHGQYYCLANNSVSNVTSSIAKLTVFFKPDISTH-PSPQTVTEGENVTLSCA 1160 Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725 E R P+ +WFK+ G +++ G L + DD G Y C A N + Sbjct: 1161 AEGRPTPSY--QWFKDDSPFDAGNNARASLSEG--NLIFTKVSRDDHGQYYCLANNSVSN 1216 Query: 2726 AVST 2729 S+ Sbjct: 1217 VTSS 1220 Score = 39.1 bits (87), Expect = 0.086 Identities = 54/222 (24%), Positives = 84/222 (37%), Gaps = 42/222 (18%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F++ L +E N+ L C+LE G P V W + + SR Sbjct: 1320 PKFLESLKPKETRNETDNLTLTCKLE--GKPQATVVWLKDNTELKPDSR----------- 1366 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296 L I +S D+GE T+ +N S S R IVT + Sbjct: 1367 LIITQPSSVDSGESTLTIINLDRSDEASYKCRANNTVGIVTSSNTT-------------- 1412 Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356 +TV P+F + N+ EG++V+L C+L+ V W G + T Sbjct: 1413 --------VTVQYPPKFFKIPDNVIKTEGSSVNLTCQLE--CKPKCSVTWLIGGSLLDTS 1462 Query: 1357 HR----FRPAYEFDYVALDLLS-VYPEDSGVYTCQATNQLGE 1393 +P + + + ++S + D YTC+A N GE Sbjct: 1463 SDRISVTQPENDGNETSFLMISNLNRTDEASYTCRAKNAAGE 1504 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH----DF 2431 P F + L+ + E C+L G P V W ++ ++ SR+ T D Sbjct: 1320 PKFLESLKPKETRNETDNLTLTCKL--EGKPQATVVWLKDNTELKPDSRLIITQPSSVDS 1377 Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLG 2458 G ++TI ++ DE Y CRA+N +G Sbjct: 1378 GESTLTIINLDRSDEASYKCRANNTVG 1404 Score = 39.1 bits (87), Expect = 0.086 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 8/90 (8%) Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--- 690 YPP F +P +V EG ++ ++E P + WL G ++ SS S+ + Sbjct: 1417 YPPKFFKIP-DNVIKTEGSSVNLTCQLEC--KPKCSVTWLIGGSLLDTSSDRISVTQPEN 1473 Query: 691 -FGYISLDMLS-LNIQDSGEYTCRAVSATG 718 S M+S LN D YTCRA +A G Sbjct: 1474 DGNETSFLMISNLNRTDEASYTCRAKNAAG 1503 Score = 39.1 bits (87), Expect = 0.086 Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 16/138 (11%) Query: 3776 WGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQ 3835 +G+ T++ IT + D S +GEK E +G ++ V+ PPK +T Sbjct: 1673 YGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSE--QGLLT--------VNYPPKILTP 1722 Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP-SGHRYRT---VYDMGFVSLDI 3891 K+ T+ E V C VE K P++ ++W + S +T V +G +L I Sbjct: 1723 PKNVTITEGNDVTLSCEVEGK--PEVTVDWLNGSTPIELSSVIEKTGLAVTGIGLSNLTI 1780 Query: 3892 LYVYAEDSGEYICRAVND 3909 V G Y CRA D Sbjct: 1781 KGVSRYYEGSYKCRAKRD 1798 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH----DF 2431 P F + L+ + E C+L G P V W ++ ++ SR+ T D Sbjct: 1960 PKFLESLKPEETRNETDNLTLTCKL--EGKPLATVVWLKDNTELKPDSRLIITQPSSVDS 2017 Query: 2432 GYVSMTISHVRDEDEGVYMCRASN 2455 G ++TI +V DE Y CRA+N Sbjct: 2018 GESTLTIINVNRHDEAYYKCRANN 2041 Score = 39.1 bits (87), Expect = 0.086 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 3/79 (3%) Query: 395 VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454 +KV D V GK C G P P +W +D R D + + + Sbjct: 2564 LKVSDDGKVDVGKQISLVCEAGGNPIPTFSWLKDDENFRIDI---VATKSDDKRNMTLRE 2620 Query: 455 VTLSDSGVVTCVARNKSGE 473 V G TCVARN G+ Sbjct: 2621 VQRFYGGDYTCVARNGIGQ 2639 Score = 38.7 bits (86), Expect = 0.11 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 6/72 (8%) Query: 944 EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS-ANLTIV 1002 +W KD P +A + G + T V+ D G Y C A N++ T+S A LT+ Sbjct: 1078 QWFKDDSPFDAKYNTRASLSEGNLIFT--KVSRDDHGQYYCLANNSVSNVTSSIAKLTVF 1135 Query: 1003 TKKDIIAESQHP 1014 K DI S HP Sbjct: 1136 FKPDI---STHP 1144 Score = 38.7 bits (86), Expect = 0.11 Identities = 37/125 (29%), Positives = 55/125 (44%), Gaps = 11/125 (8%) Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-TIGHRFRPIH- 1497 V P+F PK + V E V C+LE V W K+ P+ T R H Sbjct: 2254 VQYPPKFFQSPKD-KTVTEKSDVTLTCQLE--CKPKCSVTWLKDNTPLDTSPVRITVTHP 2310 Query: 1498 -DFGYV--ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR--LTCRSTTDIVRSTQNEAGL 1552 FG +L I +L+ D Y+C+A+N G D+ S + LT I +++ N+ Sbjct: 2311 GSFGNTTSSLTITNLVRTDEARYSCKAINAAG-DKTSEQGLLTVNFPPRIFKTSANQTRE 2369 Query: 1553 EQIQV 1557 E Q+ Sbjct: 2370 EGQQI 2374 Score = 38.7 bits (86), Expect = 0.11 Identities = 44/160 (27%), Positives = 61/160 (38%), Gaps = 17/160 (10%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI---NDFG 3613 PP+F +P D ++E S C+L S V W + PL T T+ FG Sbjct: 2257 PPKFFQSPKDKTVTEKSDVTLTCQLECKPKCS--VTWLKDNTPLDTSPVRITVTHPGSFG 2314 Query: 3614 FVI--LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES 3671 L I + + D Y+CKA N G+ T QG++ P FK T + Sbjct: 2315 NTTSSLTITNLVRTDEARYSCKAINAAGDKT--------SEQGLLTVNFPPRIFK--TSA 2364 Query: 3672 IQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGG 3711 Q EE +E ++ P KD DV G Sbjct: 2365 NQTREEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADG 2404 Score = 38.3 bits (85), Expect = 0.15 Identities = 42/188 (22%), Positives = 63/188 (33%), Gaps = 15/188 (7%) Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684 I+ + K V G + F+C P++ W K I S D TL + Sbjct: 596 IVTHPQPKSVFTGDDVTFTCNATALAAPSIWWQKDGVNITIS---------DGSTLNLVN 646 Query: 4685 AFPEDEGDYKCVAYNSAGRVTV-AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743 D G+Y CVA T AA L V P N PA + + + Sbjct: 647 VKEGDSGNYTCVAEAGENTTTSDAAFLSVKLPPVITNHPA-----NQTANKDENVTIACS 701 Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803 + WL+ + + D ++ NN L I D G++ C + Sbjct: 702 ANGTEPFNVIWLKNNEVYDFSSDSRVHESHNNLTLEIFGVLPNDHGSYQCDVSNGRTDKS 761 Query: 4804 TSAKLVVK 4811 L+VK Sbjct: 762 YPGTLIVK 769 Score = 38.3 bits (85), Expect = 0.15 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 4/77 (5%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG ++ FEC+ + + PT + W N L + + + ++ L IT+ DSG Y Sbjct: 876 EGWSVTFECHTKGNPPPT--VTWLKNGSALNTSVDPRFYSNGTH--LMITNVNRTDSGAY 931 Query: 2847 TCKATNSKGSATTSGSL 2863 C A++ G TT SL Sbjct: 932 RCNASSILGVITTKASL 948 Score = 38.3 bits (85), Expect = 0.15 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 7/100 (7%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT----TFFNF 964 P+F +K + + E +LE G V WLKD ++ SR+ + + Sbjct: 1320 PKFLESLKPKETRNETDNLTLTCKLE--GKPQATVVWLKDNTELKPDSRLIITQPSSVDS 1377 Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 G LTI ++ D Y CRA N +G TS+N T+ + Sbjct: 1378 GESTLTIINLDRSDEASYKCRANNTVG-IVTSSNTTVTVQ 1416 Score = 38.3 bits (85), Expect = 0.15 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 7/88 (7%) Query: 3826 VSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTV-- 3881 V+ PPKF+ +K T+ E++ + C++E K P + W + N +L P T Sbjct: 1514 VNYPPKFLQSLKDEETLNETDNLTLTCKLEGK--PLATVVWLKDNTELEPDSRLIITQPS 1571 Query: 3882 -YDMGFVSLDILYVYAEDSGEYICRAVN 3908 D G +L I+ V+ D Y C A N Sbjct: 1572 SVDSGESTLTIINVHRHDEAYYKCLANN 1599 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/97 (26%), Positives = 37/97 (38%), Gaps = 6/97 (6%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH----DF 2164 P FL +L E L E D C++E P T+ W + ++ R T D Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLIITQPSSVDS 1575 Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 G L I+ + D Y C A N + +T V Sbjct: 1576 GESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSV 1612 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG+N+ C E P+ +WF ++ P + +Y + S +L T +D G Y Sbjct: 1059 EGENVTLLCVAEGRPSPSY--QWFKDDSPFDA--KYNTRASLSEGNLIFTKVSRDDHGQY 1114 Query: 2847 TCKATNSKGSATTS 2860 C A NS + T+S Sbjct: 1115 YCLANNSVSNVTSS 1128 Score = 37.9 bits (84), Expect = 0.20 Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 8/94 (8%) Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDS-SRITKTH 2429 V + P F Q +N + + E C+L P V W ++ ++ S RIT TH Sbjct: 1613 VVQYPPKFFQSPKN-ETVTEKSNVTLTCQL--ECKPKCSVTWLKDNTPLDTSPDRITVTH 1669 Query: 2430 DFGY----VSMTISHVRDEDEGVYMCRASNLLGE 2459 Y S+TI+++ DE Y C+A N GE Sbjct: 1670 PGSYGNTTSSLTITNLVRTDEARYSCKAINAAGE 1703 Score = 37.9 bits (84), Expect = 0.20 Identities = 47/212 (22%), Positives = 80/212 (37%), Gaps = 13/212 (6%) Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461 +G + + PP + + E E +G+P + W + PI+ S + Sbjct: 1708 QGLLTVNYPPKILTPPKNVTITEGNDVTLSCEVEGKPEVTVDWLNGSTPIELSSVIE--- 1764 Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521 K+ L + + + + + V+ G+ KC A + V +L + Sbjct: 1765 ---KTGLAVTGIGLSNLTI-KGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPE 1820 Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI----LEEDGTYTLLILEAY 4577 + L L K+ G V WLK+ +++PD R I L E G TL I+ Sbjct: 1821 ETRNETDNLT-LTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVN 1879 Query: 4578 PQDSGKYECVAINSAG-EARCDAECVVSLPAT 4608 D Y+C A N+ A + VV + T Sbjct: 1880 RHDEAYYKCRANNTVNTTASTNTSVVVQITVT 1911 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G T +W KD P +A + + G + T ++ D G Y C A N++ T+S Sbjct: 979 GRPTPSYQWFKDDSPFDAENNTRASLSEGNLIFT--KISRDDHGQYYCLANNSVSNVTSS 1036 Query: 997 -ANLTIVTKKDI 1007 A L + K DI Sbjct: 1037 IAQLNVFFKPDI 1048 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 7/89 (7%) Query: 636 PPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF----TSIFR 690 PP+F+ LK T E + ++E G P + WLK+ ++ SR S Sbjct: 1319 PPKFLESLKPKETRNETDNLTLTCKLE--GKPQATVVWLKDNTELKPDSRLIITQPSSVD 1376 Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGV 719 G +L +++L+ D Y CRA + G+ Sbjct: 1377 SGESTLTIINLDRSDEASYKCRANNTVGI 1405 Score = 37.5 bits (83), Expect = 0.26 Identities = 40/156 (25%), Positives = 60/156 (38%), Gaps = 13/156 (8%) Query: 3542 SGTVDTLTPEAESG----NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597 + TVDT T + PP+F +P + ++E S+ C+L S V W + Sbjct: 1598 NNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCS--VTWLKDN 1655 Query: 3598 KPLLTGSRVKTINDFGFV-----ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 PL T T+ G L I + + D Y+CKA N GE T L Sbjct: 1656 TPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVNY 1715 Query: 3653 QGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE 3688 IL P G + E + + E+T++ Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCE--VEGKPEVTVD 1749 Score = 37.1 bits (82), Expect = 0.35 Identities = 43/155 (27%), Positives = 62/155 (40%), Gaps = 22/155 (14%) Query: 1652 CRAINALGEAVTSG-IAIVHSKKSIY---LESQHEGALPRLNQLE----DTSKYQRHSAQ 1703 C A A GE +TSG I H K I+ + + + P+++ + T Y R Sbjct: 528 CLATVAGGENITSGCIKTAHGKCCIFPFVYNATSQYSAPKVDHNKAWCGTTDNYDRDGLW 587 Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763 D V+ + T P V F + P + W ++GV I S+ T Sbjct: 588 DSVLGTLSIVTHPQPK-SVFTGDDVTFTCNATALAAPS--IWWQKDGVNITISDGST--- 641 Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798 LN+ V DSG YTC + E GE T+S Sbjct: 642 ------LNLVNVKEGDSGNYTC--VAEAGENTTTS 668 Score = 37.1 bits (82), Expect = 0.35 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 5/93 (5%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P+F K + + EG FE + G+ + V WLK G V S + F Sbjct: 772 PQFIVEPKGKTTT-EGQVVKFEC--QTTGNPSPNVTWLKSGSAVNTS--VDPRFYSNDTI 826 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 L I +V+ D+G Y+C A N +G + A L + Sbjct: 827 LMITNVSRIDSGTYSCNASNELGIISAEAALDV 859 Score = 37.1 bits (82), Expect = 0.35 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 9/93 (9%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG--SRVHTLNDFGF 3752 P+F VE K EG V F+C+ G+P+ + W +G T R ++ ND Sbjct: 772 PQFIVEPKGKTTT-EGQVVKFECQT--TGNPSPNVTWLKSGSAVNTSVDPRFYS-NDTIL 827 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 + ++ I D+G Y+C A+N+ G + A + Sbjct: 828 MITNVSRI---DSGTYSCNASNELGIISAEAAL 857 Score = 37.1 bits (82), Expect = 0.35 Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 6/112 (5%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 KP+ T Q ++ EG E G T +W KD P +A + + G + Sbjct: 1137 KPDISTHPSPQ-TVTEGENVTLSCAAE--GRPTPSYQWFKDDSPFDAGNNARASLSEGNL 1193 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTS-ANLTIVTKKDIIAESQHPGGLE 1018 T V+ D G Y C A N++ T+S LT+ I Q+ +E Sbjct: 1194 IFT--KVSRDDHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTKVE 1243 Score = 37.1 bits (82), Expect = 0.35 Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 6/128 (4%) Query: 3410 TSVEEEKGKAPVFTVP--LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467 ++V K + VF P ++ +N + E T T DP V W +G +L A Sbjct: 1215 SNVTSSKVQLTVFFAPSITTHPQNQTKVEGEIVTLSCTVTGDPVPTVYWSRDGSNLTA-- 1272 Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKG 3527 R + L+I ED G Y+C A+NN + A++ LES PK Sbjct: 1273 -LRYLVEPSNT-LKIENLTREDEGSYICHAFNNVSSTSSDAAVLTVNYPPKFLESLKPKE 1330 Query: 3528 MEGTIDKI 3535 D + Sbjct: 1331 TRNETDNL 1338 Score = 37.1 bits (82), Expect = 0.35 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 8/93 (8%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTL---ND 3749 PP+F +I DN+ EG V+ C++E P + W G T S R+ ND Sbjct: 1418 PPKF-FKIPDNVIKTEGSSVNLTCQLEC--KPKCSVTWLIGGSLLDTSSDRISVTQPEND 1474 Query: 3750 FGFIA-LDIDYIYARDAGEYTCRATNKWGSATT 3781 + L I + D YTCRA N G T+ Sbjct: 1475 GNETSFLMISNLNRTDEASYTCRAKNAAGEKTS 1507 Score = 37.1 bits (82), Expect = 0.35 Identities = 52/246 (21%), Positives = 92/246 (37%), Gaps = 31/246 (12%) Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL----TTM 1762 + P P K++ + E + G P++ V+WL PIE S+ + + Sbjct: 1713 VNYPPKILTPPKNVTITEGNDVTLSCEV--EGKPEVTVDWLNGSTPIELSSVIEKTGLAV 1770 Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRA---------------INELGEAVTSSTLFVQSKAS 1807 G L +K V+ G+Y CRA +N LG T + Sbjct: 1771 TGIGLSNLTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLT 1830 Query: 1808 LQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL---SEGQSAHY 1864 L + + + L + L+D++ + + D + + Q P + K+ + A+Y Sbjct: 1831 LTCKLEGK-PLATVVWLKDNT--ELKPDSRLIITQ-PSLVESGESTLKIINVNRHDEAYY 1886 Query: 1865 ECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINN 1924 +CR + V+Q + S ++L I + D Y+CKAIN Sbjct: 1887 KCRANNTVNTTASTN---TSVVVQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINA 1943 Query: 1925 LGQAVS 1930 G+ S Sbjct: 1944 AGEKSS 1949 Score = 36.7 bits (81), Expect = 0.46 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 13/103 (12%) Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316 D LG +S I P+ + G D F + P + W K+G +N IT Sbjct: 588 DSVLGTLS---IVTHPQPKSVFTGDDVTFTCNATALAAPSIWWQKDG---VN------IT 635 Query: 317 THNHTTLRVRNTQKSDSGHYTLLAE-NPNGCIVTSGYLAVESP 358 + +TL + N ++ DSG+YT +AE N + +L+V+ P Sbjct: 636 ISDGSTLNLVNVKEGDSGNYTCVAEAGENTTTSDAAFLSVKLP 678 Score = 36.7 bits (81), Expect = 0.46 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 7/94 (7%) Query: 770 PQFIRPLQDLGELQ-EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828 PQFI ++ G+ EG+ FE Q T +P+ V W K G + S + F Sbjct: 772 PQFI--VEPKGKTTTEGQVVKFECQTT--GNPSPNVTWLKSGSAVNTS--VDPRFYSNDT 825 Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 L I ++ D+G+Y+ A N+LG + A++ V Sbjct: 826 ILMITNVSRIDSGTYSCNASNELGIISAEAALDV 859 Score = 36.7 bits (81), Expect = 0.46 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 6/106 (5%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P T ++ T E E V C V DP + W R+G L + RY +L Sbjct: 1230 PSITTHPQNQTKVEGEIVTLSCTVTG--DPVPTVYWSRDGSNL-TALRYLVEPSN---TL 1283 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935 I + ED G YIC A N+ + A + P L++ P+ Sbjct: 1284 KIENLTREDEGSYICHAFNNVSSTSSDAAVLTVNYPPKFLESLKPK 1329 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 4/66 (6%) Query: 795 TPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEA 854 T DP V W +DG +TA + N +L I +L ED GSY A N + Sbjct: 1252 TVTGDPVPTVYWSRDGSNLTALRYLVEPSN----TLKIENLTREDEGSYICHAFNNVSST 1307 Query: 855 ISTASI 860 S A++ Sbjct: 1308 SSDAAV 1313 Score = 36.7 bits (81), Expect = 0.46 Identities = 28/82 (34%), Positives = 35/82 (42%), Gaps = 7/82 (8%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT----HDF 2431 P P +N+ I EG C + G P + V+W IE SS I KT Sbjct: 1717 PKILTPPKNV-TITEGNDVTLSCEV--EGKPEVTVDWLNGSTPIELSSVIEKTGLAVTGI 1773 Query: 2432 GYVSMTISHVRDEDEGVYMCRA 2453 G ++TI V EG Y CRA Sbjct: 1774 GLSNLTIKGVSRYYEGSYKCRA 1795 Score = 36.3 bits (80), Expect = 0.61 Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 9/76 (11%) Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 +V G+ V A P I WQKDGV I T STL++ K D+ Sbjct: 604 SVFTGDDVTFTCNATALAAPSIWWQKDGVNI---------TISDGSTLNLVNVKEGDSGN 654 Query: 561 YQCTAQNVAGSTATRA 576 Y C A+ +T + A Sbjct: 655 YTCVAEAGENTTTSDA 670 Score = 36.3 bits (80), Expect = 0.61 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%) Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449 EGQ F+C+ G+P+ V W ++ + S + + I++V D G Y Sbjct: 785 EGQVVKFECQT--TGNPSPNVTWLKSGSAVNTS--VDPRFYSNDTILMITNVSRIDSGTY 840 Query: 2450 MCRASNLLG 2458 C ASN LG Sbjct: 841 SCNASNELG 849 Score = 36.3 bits (80), Expect = 0.61 Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 4/102 (3%) Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 + P F +D E + FE G+P V WL+NG + S + G Sbjct: 859 VRYGPEFVNVPQDKTPNEGWSVTFECHT--KGNPPPTVTWLKNGSALNTSVD-PRFYSNG 915 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 L + VN DSG Y C A + LG T ++L V K + Sbjct: 916 -THLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 5/91 (5%) Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912 P ++EGQ+ C E P P+ +W+ + + + R S G L + + Sbjct: 962 PQTVTEGQNVTLLCVAEGRPTPSY--QWFKDDSPFDAENNTRASLSEG--NLIFTKISRD 1017 Query: 1913 DSGEYTCKAINNLGQAVSSI-RLNVQSKESI 1942 D G+Y C A N++ SSI +LNV K I Sbjct: 1018 DHGQYYCLANNSVSNVTSSIAQLNVFFKPDI 1048 Score = 36.3 bits (80), Expect = 0.61 Identities = 37/155 (23%), Positives = 58/155 (37%), Gaps = 6/155 (3%) Query: 1261 AHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNI 1320 A +A + E + I T + + L ++ + +TV AP + N Sbjct: 1180 AGNNARASLSEGNLIFTKVSRDDHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQ 1239 Query: 1321 ETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380 VEG V L C + GD V W +G + T R+ L + ++ ED Sbjct: 1240 TKVEGEIVTLSCTV--TGDPVPTVYWSRDGSNL-TALRYLVEPSN---TLKIENLTREDE 1293 Query: 1381 GVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415 G Y C A N + + A+ + LES P Sbjct: 1294 GSYICHAFNNVSSTSSDAAVLTVNYPPKFLESLKP 1328 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 6/98 (6%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR----Y 1893 + VN P+F+ L +E + C++E P V W + L+ R Sbjct: 1314 LTVNYPPKFLESLKPKETRNETDNLTLTCKLE--GKPQATVVWLKDNTELKPDSRLIITQ 1371 Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931 +S D G + L I+ + D Y C+A N +G SS Sbjct: 1372 PSSVDSGESTLTIINLDRSDEASYKCRANNTVGIVTSS 1409 Score = 36.3 bits (80), Expect = 0.61 Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 9/127 (7%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ-SGHRYRTS 1896 V V P+F + K +EG S + C++E P V W G +L S R + Sbjct: 1413 VTVQYPPKFFKIPDNVIK-TEGSSVNLTCQLEC--KPKCSVTWLIGGSLLDTSSDRISVT 1469 Query: 1897 ---NDFGFAA-LDILTVYGEDSGEYTCKAINNLGQAVS-SIRLNVQSKESIIRDSQHESA 1951 ND + L I + D YTC+A N G+ S S+ L V ++ + E Sbjct: 1470 QPENDGNETSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEET 1529 Query: 1952 LEKIQYL 1958 L + L Sbjct: 1530 LNETDNL 1536 Score = 36.3 bits (80), Expect = 0.61 Identities = 16/46 (34%), Positives = 22/46 (47%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155 PP F +PD V EG C++ PK V WL+ G+ + S Sbjct: 1418 PPKFFKIPDNVIKTEGSSVNLTCQLECKPKCSVTWLIGGSLLDTSS 1463 Score = 35.9 bits (79), Expect = 0.80 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 5/99 (5%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P F V + + EG V F+C + G+P + W NG T ++ + Sbjct: 863 PEF-VNVPQDKTPNEGWSVTFECHTK--GNPPPTVTWLKNGSALNTSVDPRFYSNGTHLM 919 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793 I + D+G Y C A++ G TT A + K DI Sbjct: 920 --ITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956 Score = 35.9 bits (79), Expect = 0.80 Identities = 57/235 (24%), Positives = 94/235 (40%), Gaps = 41/235 (17%) Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490 K + ++ +V P+F+ K E + E ++ CKLE + V W K+ + Sbjct: 1505 KTSGSVNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLEGKPLAT--VVWLKDNTELEPD 1562 Query: 1491 HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550 R L I + DSG T +N+ DE + +T D ST N + Sbjct: 1563 SR-----------LIITQPSSVDSGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTS 1611 Query: 1551 GLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLK 1610 V++ K+ ++ + VT ++ + T +E K Sbjct: 1612 -----VVVQYPPKFFQSPKNETVTEKSNVTLTC--QLECKP----------------KCS 1648 Query: 1611 VEWYHNNKPLK-SGSRFTETN--NFGFV--ALDIMSCLPEDSGTYTCRAINALGE 1660 V W +N PL S R T T+ ++G +L I + + D Y+C+AINA GE Sbjct: 1649 VTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGE 1703 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 8/73 (10%) Query: 937 GDSTLRVEWLKDGRPVEASSRITT------FFNFGYVALTIKSVTVHDAGHYTCRAYNAI 990 G S V W KDG V A TT + +LTIK+V D G Y C A N++ Sbjct: 2385 GTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSL 2444 Query: 991 G--QATTSANLTI 1001 +T S +LT+ Sbjct: 2445 KTVYSTPSIHLTV 2457 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 5/97 (5%) Query: 1847 ITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI 1906 I+ P ++EG++ C E P P+ +W+ + + +Y T L Sbjct: 1048 ISTYPSPQTITEGENVTLLCVAEGRPSPSY--QWFKDDSPFDA--KYNTRASLSEGNLIF 1103 Query: 1907 LTVYGEDSGEYTCKAINNLGQAVSSI-RLNVQSKESI 1942 V +D G+Y C A N++ SSI +L V K I Sbjct: 1104 TKVSRDDHGQYYCLANNSVSNVTSSIAKLTVFFKPDI 1140 Score = 35.5 bits (78), Expect = 1.1 Identities = 33/137 (24%), Positives = 52/137 (37%), Gaps = 12/137 (8%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I TD +Y+CRA N G+ V+ + P+F +++ E L + + Sbjct: 1481 LMISNLNRTDEASYTCRAKNAAGEKTSG----SVNLAVNYPPKFLQSLKDEETLNETDNL 1536 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRI----KTVSDFGFVVLDIAYTQNHDSGEYV 3223 C + P + W + + +R+ + D G L I HD Y Sbjct: 1537 TLTCKL--EGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYK 1594 Query: 3224 CRAYNKYGEDFTRATIN 3240 C A N D T +T N Sbjct: 1595 CLANNTV--DTTTSTTN 1609 Score = 35.5 bits (78), Expect = 1.1 Identities = 89/390 (22%), Positives = 144/390 (36%), Gaps = 63/390 (16%) Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGT-NVHLECRLQPVGDQTMRVEWFCNGKPI 1353 A+R E F +L ET T N+ L C+L+ G V W + + Sbjct: 1795 AKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTEL 1852 Query: 1354 KTGHRF---RPAY-EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409 K R +P+ E L +++V D Y C+A N + S V+ + + Sbjct: 1853 KPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVN-TTASTNTSVVVQITVT 1911 Query: 1410 LESQHPSGLEKIQYLE----DTSRY--KKTDIIDE--------SVTIKPRFVTRPKSIEN 1455 + + + D +RY K + E +V P+F+ K E Sbjct: 1912 HPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEET 1971 Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515 E ++ CKLE + V W K+ + R L I + DSG Sbjct: 1972 RNETDNLTLTCKLEGKPLAT--VVWLKDNTELKPDSR-----------LIITQPSSVDSG 2018 Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTT 1575 T +N+ DE + +T D ST N + V++ K+ ++ + VT Sbjct: 2019 ESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTS-----VVVQYPPKFFQSPKNETVTE 2073 Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLK-SGSRFTETN--NF 1632 ++ + T +E K V W +N PL S R T T+ ++ Sbjct: 2074 KSNVTLTC--QLECKP----------------KCSVTWLKDNTPLDTSPDRITVTHPGSY 2115 Query: 1633 GFV--ALDIMSCLPEDSGTYTCRAINALGE 1660 G +L I + + D Y+C+AINA GE Sbjct: 2116 GNTTSSLTITNLVRTDEARYSCKAINAAGE 2145 Score = 35.5 bits (78), Expect = 1.1 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 7/101 (6%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPK-LRIEWYRNG-KLLPSGHRYRTVYD 3883 V+ PP+ + T EE + + F C VE KE + W ++G + G+R Sbjct: 2353 VNFPPRIFKTSANQTREEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTAQSP 2412 Query: 3884 MGFV-----SLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 ++ SL I V ED G Y C A N ++ +I Sbjct: 2413 TNYMGPSTASLTIKNVQREDEGFYQCFAENSLKTVYSTPSI 2453 Score = 35.1 bits (77), Expect = 1.4 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 5/93 (5%) Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301 P+F+ E +G T EG+ FECQ PN + + +G A+ ++ F Sbjct: 772 PQFIVEPKGKTTT-EGQVVKFECQTTGNPSPN--VTWLKSGSAVNTSV--DPRFYSNDTI 826 Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 L I + D+G YS A N LG ++ ++ V Sbjct: 827 LMITNVSRIDSGTYSCNASNELGIISAEAALDV 859 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 5/88 (5%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P +TH S + EGQ+V L E R P+ +WFK+ +++ G Sbjct: 954 PDISTH-PSPQTVTEGQNVTLLCVAEGRPTPSY--QWFKDDSPFDAENNTRASLSEG--N 1008 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVST 2729 L + DD G Y C A N + S+ Sbjct: 1009 LIFTKISRDDHGQYYCLANNSVSNVTSS 1036 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 4/74 (5%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG N+ C E PT +WF ++ P + +++ S +L T +D G Y Sbjct: 967 EGQNVTLLCVAEGR--PTPSYQWFKDDSPFDAENNTRAS--LSEGNLIFTKISRDDHGQY 1022 Query: 2847 TCKATNSKGSATTS 2860 C A NS + T+S Sbjct: 1023 YCLANNSVSNVTSS 1036 Score = 35.1 bits (77), Expect = 1.4 Identities = 34/137 (24%), Positives = 50/137 (36%), Gaps = 12/137 (8%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I TD YSC+A N G+ L V+ P+F ++ E + + Sbjct: 1923 LTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN----YPPKFLESLKPEETRNETDNL 1978 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS----DFGFVVLDIAYTQNHDSGEYV 3223 C + P + W + ++ +R+ D G L I HD Y Sbjct: 1979 TLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINVNRHDEAYYK 2036 Query: 3224 CRAYNKYGEDFTRATIN 3240 CRA N D T +T N Sbjct: 2037 CRANNTV--DTTTSTTN 2051 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 9/99 (9%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRF----KTYYDF 1232 P F++ L +E N+ L C+LE G P V W + + SR + + Sbjct: 2159 PKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSLVES 2216 Query: 1233 GFVALDIIHATSADTGEYTVRA---VNHLGSAHTSAIVR 1268 G L II+ D Y RA VN S +TS +V+ Sbjct: 2217 GESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQ 2255 Score = 35.1 bits (77), Expect = 1.4 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH----DF 2431 P F + L+ + E C+L G P V W ++ ++ SR+ T + Sbjct: 2159 PKFLESLKPEETRNETDNLTLTCKL--EGKPLATVVWLKDNTELKPDSRLIITQPSLVES 2216 Query: 2432 GYVSMTISHVRDEDEGVYMCRASN 2455 G ++ I +V DE Y CRA+N Sbjct: 2217 GESTLKIINVNRHDEAYYKCRANN 2240 Score = 34.7 bits (76), Expect = 1.9 Identities = 26/116 (22%), Positives = 41/116 (35%), Gaps = 5/116 (4%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885 V PP + T + E V C E + W +N ++ R Sbjct: 675 VKLPPVITNHPANQTANKDENVTIACSANGTEP--FNVIWLKNNEVYDFSSDSRVHESHN 732 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSE 3941 ++L+I V D G Y C N + T+ K P I++ P+G +E Sbjct: 733 NLTLEIFGVLPNDHGSYQCDVSNGRTDKSYPGTLIVKYAPQFIVE---PKGKTTTE 785 Score = 34.7 bits (76), Expect = 1.9 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 5/99 (5%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+F+ QD T EG S FE +P V W NG L R F+ G + Sbjct: 863 PEFVNVPQDKTPN-EGWSVTFECHTK--GNPPPTVTWLKNGSALNTSVDPR-FYSNGTHL 918 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380 + I +SG Y C A++ LG +TKA+L K ++ Sbjct: 919 M-ITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956 Score = 34.7 bits (76), Expect = 1.9 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449 EG + F+C G+P V W +N + ++S + + G + I++V D G Y Sbjct: 876 EGWSVTFECHT--KGNPPPTVTWLKNGSAL-NTSVDPRFYSNG-THLMITNVNRTDSGAY 931 Query: 2450 MCRASNLLG 2458 C AS++LG Sbjct: 932 RCNASSILG 940 Score = 34.7 bits (76), Expect = 1.9 Identities = 28/101 (27%), Positives = 38/101 (37%), Gaps = 5/101 (4%) Query: 3707 VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAG 3766 V EG V C E G PT WF + PF G+ G L + D G Sbjct: 1149 VTEGENVTLSCAAE--GRPTPSYQWFKDDSPFDAGNNARASLSEG--NLIFTKVSRDDHG 1204 Query: 3767 EYTCRATNKWGSATTT-AKITCSAKRDIVLESQLPQGMSGE 3806 +Y C A N + T++ ++T I Q + GE Sbjct: 1205 QYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTKVEGE 1245 Score = 34.7 bits (76), Expect = 1.9 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 4/66 (6%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMH----DFGYVALNMKYVNPEDSGTYTCRAINELGE 1793 G P+ V WL++ ++ +RL D G L + ++ D +Y CRA N +G Sbjct: 1346 GKPQATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINLDRSDEASYKCRANNTVGI 1405 Query: 1794 AVTSST 1799 +S+T Sbjct: 1406 VTSSNT 1411 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 6/93 (6%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN----D 3749 PP+F +KD + E + C++E G P + W + SR+ D Sbjct: 1517 PPKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLIITQPSSVD 1574 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 G L I ++ D Y C A N + T+T Sbjct: 1575 SGESTLTIINVHRHDEAYYKCLANNTVDTTTST 1607 Score = 34.7 bits (76), Expect = 1.9 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT 4150 PP ++ P VT+ EG C V G P+ V W LNG+T Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCEVEGKPEVTVDW-LNGST 1755 Score = 34.7 bits (76), Expect = 1.9 Identities = 36/126 (28%), Positives = 51/126 (40%), Gaps = 10/126 (7%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNM-RVEWYFNGK-VLQSGHRYRT 1895 + VN PR T+ EGQ + C +E + V W +G V G+R Sbjct: 2351 LTVNFPPRIFKTSANQTR-EEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTA 2409 Query: 1896 SNDFGF-----AALDILTVYGEDSGEYTCKAINNLGQAVS--SIRLNVQSKESIIRDSQH 1948 + + A+L I V ED G Y C A N+L S SI L V +I S Sbjct: 2410 QSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSLKTVYSTPSIHLTVHFNSTIFECSGA 2469 Query: 1949 ESALEK 1954 ++ E+ Sbjct: 2470 QNVTER 2475 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 4/78 (5%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 GD V W +DG + A + N L I+++T D G Y C A+N + ++ Sbjct: 1255 GDPVPTVYWSRDGSNLTALRYLVEPSN----TLKIENLTREDEGSYICHAFNNVSSTSSD 1310 Query: 997 ANLTIVTKKDIIAESQHP 1014 A + V ES P Sbjct: 1311 AAVLTVNYPPKFLESLKP 1328 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 9/81 (11%) Query: 2386 DNI--QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS-RITKT---HDFGYVS-MTI 2438 DN+ EG + + C+L P V W L++ SS RI+ T +D S + I Sbjct: 1426 DNVIKTEGSSVNLTCQL--ECKPKCSVTWLIGGSLLDTSSDRISVTQPENDGNETSFLMI 1483 Query: 2439 SHVRDEDEGVYMCRASNLLGE 2459 S++ DE Y CRA N GE Sbjct: 1484 SNLNRTDEASYTCRAKNAAGE 1504 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/104 (24%), Positives = 39/104 (37%), Gaps = 2/104 (1%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 PP T P++ +++ + C V W N + S + + Sbjct: 678 PPVITNHPANQTANKDENVTIACSAN--GTEPFNVIWLKNNEVYDFSSDSRVHESHNNLT 735 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660 LEI GV D G Y C +N + + L VK I+EP+ Sbjct: 736 LEIFGVLPNDHGSYQCDVSNGRTDKSYPGTLIVKYAPQFIVEPK 779 Score = 33.9 bits (74), Expect = 3.2 Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 13/99 (13%) Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF- 3477 AP F V + EG+ FE + T PN V W LK+GS T D F Sbjct: 771 APQFIVEPKG-KTTTEGQVVKFECQTTGNPSPN--VTW------LKSGSAVNTSVDPRFY 821 Query: 3478 ---VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 IL I+ DSG Y C A N G A++ V+ Sbjct: 822 SNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVR 860 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 6/97 (6%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 PQF K TEG V E T +P+ V W +G V + L Sbjct: 772 PQFIVEPKGKTTTEGQVVKFECQTT--GNPSPNVTWLKSGSAVNTS--VDPRFYSNDTIL 827 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074 I D+GTY C A+N +G + ++ +D + G Sbjct: 828 MITNVSRIDSGTYSCNASNELG--IISAEAALDVRYG 862 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 12/81 (14%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD----ITHTYEED 2842 EG + FEC + + +P+ + W L SG+ ++ D + S D IT+ D Sbjct: 785 EGQVVKFEC--QTTGNPSPNVTW------LKSGSAVNTSVDPRFYSNDTILMITNVSRID 836 Query: 2843 SGIYTCKATNSKGSATTSGSL 2863 SG Y+C A+N G + +L Sbjct: 837 SGTYSCNASNELGIISAEAAL 857 Score = 33.9 bits (74), Expect = 3.2 Identities = 34/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P T T+ E E V C E + P +W+++ P +Y T + +L Sbjct: 1046 PDISTYPSPQTITEGENVTLLCVAEGRPSPSY--QWFKDDS--PFDAKYNTRASLSEGNL 1101 Query: 3890 DILYVYAEDSGEYICRA---VNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQM 3946 V +D G+Y C A V++ K T+ K PD I + P+ + E +T Sbjct: 1102 IFTKVSRDDHGQYYCLANNSVSNVTSSIAKLTVFFK--PD-ISTHPSPQTVTEGENVTLS 1158 Query: 3947 EATIKKYTSEVYLTEDD 3963 A + T +DD Sbjct: 1159 CAAEGRPTPSYQWFKDD 1175 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 6/78 (7%) Query: 1611 VEWYHNNKPLKSGS-RFTETN--NFGFV--ALDIMSCLPEDSGTYTCRAINALGEAVT-S 1664 V W +N PL + R T T+ +FG +L I + + D Y+C+AINA G+ + Sbjct: 2289 VTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQ 2348 Query: 1665 GIAIVHSKKSIYLESQHE 1682 G+ V+ I+ S ++ Sbjct: 2349 GLLTVNFPPRIFKTSANQ 2366 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 9/87 (10%) Query: 2656 EGQHVYLEAQVEPR--TDPNLKIEWFKNGVTLTT-GARL--KSTFDF---GLVTLSINSL 2707 EGQ + VE + T P + W K+G +T G R +S ++ +L+I ++ Sbjct: 2370 EGQQITFTCDVEGKEGTSPP-NVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNV 2428 Query: 2708 RNDDSGIYTCKATNLLGEAVSTASIKI 2734 + +D G Y C A N L ST SI + Sbjct: 2429 QREDEGFYQCFAENSLKTVYSTPSIHL 2455 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 5/124 (4%) Query: 2606 IIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQ 2665 I + R + + L +++ V V P +T+ S + EG++V L Sbjct: 1010 IFTKISRDDHGQYYCLANNSVSNVTSSIAQLNVFFKPDISTY-PSPQTITEGENVTLLCV 1068 Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725 E R P+ +WFK+ +++ G L + DD G Y C A N + Sbjct: 1069 AEGRPSPSY--QWFKDDSPFDAKYNTRASLSEG--NLIFTKVSRDDHGQYYCLANNSVSN 1124 Query: 2726 AVST 2729 S+ Sbjct: 1125 VTSS 1128 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 8/94 (8%) Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383 EG NV L C + G + +WF + P + R + + +S +D G Y Sbjct: 1059 EGENVTLLCVAE--GRPSPSYQWFKDDSPFDAKYNTRASLSEGNLIFTKVS--RDDHGQY 1114 Query: 1384 TCQATNQLGEAVTSCA-LRVIAKKDLILESQHPS 1416 C A N + +S A L V K D+ S HPS Sbjct: 1115 YCLANNSVSNVTSSIAKLTVFFKPDI---STHPS 1145 Score = 33.5 bits (73), Expect = 4.3 Identities = 29/111 (26%), Positives = 41/111 (36%), Gaps = 7/111 (6%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P T Q+QT VE E C + GDP V W +G L + Sbjct: 1230 PSITTHPQNQTK-VEGEIVTLSCTVT--GDPVPTVYWSRDGSNLTALRYLVEPSN----T 1282 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKS 4083 + + ED G Y+C A N + A + T P +S PK ++ Sbjct: 1283 LKIENLTREDEGSYICHAFNNVSSTSSDAAVLTVNYPPKFLESLKPKETRN 1333 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%) Query: 2406 PTLKVEWFRNEKLIEDSS-RITKTH--DFGYV--SMTISHVRDEDEGVYMCRASNLLGE 2459 P V W ++ ++ S RIT TH FG S+TI+++ DE Y C+A N G+ Sbjct: 2285 PKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAINAAGD 2343 Score = 33.5 bits (73), Expect = 4.3 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 7/76 (9%) Query: 2389 QEGQTAHFDCRLI-PVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYV-----SMTISHV 2441 +EGQ F C + G V W ++ + D +R T Y+ S+TI +V Sbjct: 2369 EEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNV 2428 Query: 2442 RDEDEGVYMCRASNLL 2457 + EDEG Y C A N L Sbjct: 2429 QREDEGFYQCFAENSL 2444 Score = 33.5 bits (73), Expect = 4.3 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 6/72 (8%) Query: 804 VEWYKDGRPITA-SSRITSIFNFGYV-----SLNIMHLRAEDAGSYTVRAVNKLGEAIST 857 V W KDG +TA +R T+ Y+ SL I +++ ED G Y A N L ST Sbjct: 2391 VYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSLKTVYST 2450 Query: 858 ASIRVAARSTVT 869 SI + T Sbjct: 2451 PSIHLTVHFNST 2462 Score = 33.1 bits (72), Expect = 5.7 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 8/94 (8%) Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383 EG NV L C + G T +WF + P + R + + +S +D G Y Sbjct: 967 EGQNVTLLCVAE--GRPTPSYQWFKDDSPFDAENNTRASLSEGNLIFTKIS--RDDHGQY 1022 Query: 1384 TCQATNQLGEAVTSCA-LRVIAKKDLILESQHPS 1416 C A N + +S A L V K D+ S +PS Sbjct: 1023 YCLANNSVSNVTSSIAQLNVFFKPDI---STYPS 1053 Score = 33.1 bits (72), Expect = 5.7 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 5/93 (5%) Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 KP VTEG V L PT +W+ + P G+ + + G Sbjct: 1137 KPDISTHPSPQTVTEGENVTLSCAAE--GRPTPSYQWFKDDSPFDAGNNARASLSEGN-- 1192 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 L +D G Y C A N+V VT+S V++ Sbjct: 1193 LIFTKVSRDDHGQYYCLANNSVSN-VTSSKVQL 1224 Score = 33.1 bits (72), Expect = 5.7 Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 10/97 (10%) Query: 911 FKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS---RITTFFNFGYV 967 FK P D + EG + +LE V WL G ++ SS +T N G Sbjct: 1422 FKIP--DNVIKTEGSSVNLTCQLEC--KPKCSVTWLIGGSLLDTSSDRISVTQPENDGNE 1477 Query: 968 A--LTIKSVTVHDAGHYTCRAYNAIGQATT-SANLTI 1001 L I ++ D YTCRA NA G+ T+ S NL + Sbjct: 1478 TSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAV 1514 Score = 33.1 bits (72), Expect = 5.7 Identities = 37/130 (28%), Positives = 51/130 (39%), Gaps = 9/130 (6%) Query: 1937 QSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVE-KPQFGKPIKNAEVTEGHPV 1995 +S +II +H+ A K + + + S VV+ P+F + KN VTE V Sbjct: 1577 ESTLTIINVHRHDEAYYKC-LANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNV 1635 Query: 1996 HLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYDFGY----VALDILYAYAEDTGTY 2050 L L P V W + P+ R T+ Y +L I D Y Sbjct: 1636 TLTCQLEC--KPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARY 1693 Query: 2051 MCKATNAVGE 2060 CKA NA GE Sbjct: 1694 SCKAINAAGE 1703 Score = 33.1 bits (72), Expect = 5.7 Identities = 42/190 (22%), Positives = 67/190 (35%), Gaps = 21/190 (11%) Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR----TVYA 3102 PP+ T K++ I+EG + G + ++W IE S I V Sbjct: 1716 PPKILTPPKNVT-ITEGNDVTLSCEV--EGKPEVTVDWLNGSTPIELSSVIEKTGLAVTG 1772 Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162 G+ L I G G+Y CRA +E V+ KP T + Sbjct: 1773 IGLSNLTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRN-------- 1824 Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI----KTVSDFGFVVLDIAYTQNHD 3218 ++ + T P + W + ++ +R+ ++ + G L I HD Sbjct: 1825 --ETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHD 1882 Query: 3219 SGEYVCRAYN 3228 Y CRA N Sbjct: 1883 EAYYKCRANN 1892 Score = 33.1 bits (72), Expect = 5.7 Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 8/113 (7%) Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA-RFHITFDFGY 2299 PP+F + T V E CQ+E P + + + L ++ R +T Y Sbjct: 2059 PPKFFQSPKNET-VTEKSNVTLTCQLEC--KPKCSVTWLKDNTPLDTSPDRITVTHPGSY 2115 Query: 2300 ----VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPE 2348 SL I + V D YS KAINA G +S + ES +PE Sbjct: 2116 GNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPE 2168 Score = 33.1 bits (72), Expect = 5.7 Identities = 29/125 (23%), Positives = 47/125 (37%), Gaps = 10/125 (8%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I TD YSC+A N G+ L V+ P+F ++ E + + Sbjct: 2122 LTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN----YPPKFLESLKPEETRNETDNL 2177 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRI----KTVSDFGFVVLDIAYTQNHDSGEYV 3223 C + P + W + ++ +R+ ++ + G L I HD Y Sbjct: 2178 TLTCKL--EGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYK 2235 Query: 3224 CRAYN 3228 CRA N Sbjct: 2236 CRANN 2240 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 7/95 (7%) Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895 V++ V AP T TK+ EG+ C + P P V W +G L + RY Sbjct: 1222 VQLTVFFAPSITTHPQNQTKV-EGEIVTLSCTVTGDPVPT--VYWSRDGSNL-TALRYLV 1277 Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930 L I + ED G Y C A NN+ S Sbjct: 1278 EPS---NTLKIENLTREDEGSYICHAFNNVSSTSS 1309 Score = 32.7 bits (71), Expect = 7.5 Identities = 15/41 (36%), Positives = 19/41 (46%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 P + P T EGE C VTG P P V W +G+ + Sbjct: 1230 PSITTHPQNQTKVEGEIVTLSCTVTGDPVPTVYWSRDGSNL 1270 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 11/105 (10%) Query: 636 PPQFIVPLKSV-TAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF----TSIFR 690 PP+F+ LK T E + ++E G P + WLK+ +E SR S Sbjct: 1517 PPKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLIITQPSSVD 1574 Query: 691 FGYISLDMLSLNIQDSGEYTCRA----VSATGVAETKAVLHVTPR 731 G +L +++++ D Y C A + T T V+ P+ Sbjct: 1575 SGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQYPPK 1619 Score = 32.3 bits (70), Expect = 9.9 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 5/91 (5%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+FI + + T EGQ FE + +P V W +G + R + + I Sbjct: 772 PQFIVEPKGKTT-TEGQVVKFECQTT--GNPSPNVTWLKSGSAVNTSVDPRFYSND--TI 826 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372 L I +SG Y C A+N+LG S +A L Sbjct: 827 LMITNVSRIDSGTYSCNASNELGIISAEAAL 857 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182 EG FEC+ P++T W +G + R + L I DSGTY Sbjct: 785 EGQVVKFECQTTGNPSPNVT--WLKSGSAVNTSVDPRFYSND--TILMITNVSRIDSGTY 840 Query: 2183 MCKATNKLG 2191 C A+N+LG Sbjct: 841 SCNASNELG 849 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/85 (23%), Positives = 29/85 (34%), Gaps = 2/85 (2%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P I+ P + EG + G P P WFK+ N + + L Sbjct: 1138 PDISTHPSPQTVTEGENVTLSCAAEGRPTPSYQWFKDDSPFDAGNNARASLSEGN--LIF 1195 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTS 350 + D G Y LA N + +S Sbjct: 1196 TKVSRDDHGQYYCLANNSVSNVTSS 1220 Score = 32.3 bits (70), Expect = 9.9 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 8/93 (8%) Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA-RFHITFDFGY 2299 PP+F + T V E CQ+E P + + + L ++ R +T Y Sbjct: 1617 PPKFFQSPKNET-VTEKSNVTLTCQLEC--KPKCSVTWLKDNTPLDTSPDRITVTHPGSY 1673 Query: 2300 ----VSLDIQHCVPEDAGEYSVKAINALGHCTS 2328 SL I + V D YS KAINA G TS Sbjct: 1674 GNTTSSLTITNLVRTDEARYSCKAINAAGEKTS 1706 >SB_23359| Best HMM Match : I-set (HMM E-Value=0) Length = 367 Score = 100 bits (239), Expect = 3e-20 Identities = 101/377 (26%), Positives = 164/377 (43%), Gaps = 45/377 (11%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P P I W R+ PI N+ D ++L I F DS +A A N GTA+ Sbjct: 32 GMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAI 91 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVN-VTSGQLVRLDTKVTGTKPIDVYWL-KNGKK 4553 A L V+ + P T++ + V +G+ V L VTG + W+ N Sbjct: 92 AVLNVKAE----------PQVTVSPSRQHYVATGRQVELLCTVTGYPVPSIEWIVPNRTG 141 Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613 + P + + G ++I G+Y C+A N+ G A E VV L + + Sbjct: 142 LSPSL---VKVAQGVLKIVIENVTSPYEGRYRCMAKNNLGTA----EEVVQLFVVPNVTR 194 Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673 P + ++P+ K+V +G F+C G P P + W ++L +K + + Sbjct: 195 PNNVS-------VQPVNQKVV-KGNTATFNCTASGVPTPQLVW---ERL--GAKMPETAM 241 Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733 T+D+ L I +D G+Y+C+A NS G V AKL+V P A++P + + + Sbjct: 242 TSDKGLLTIESVGADDSGEYECIATNSEGSERVLAKLEVIVPPDV----AVSP-QQVSIN 296 Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793 G+P F+ S + W + I + ++ G VL++ +DTG + C Sbjct: 297 LGRP--FRLFCVSNPPLPLTWSKVNGTISNS---SVVVGG---VLIVQEAIIQDTGKYRC 348 Query: 4794 RATTAAGQVETSAKLVV 4810 A+ AG E A + V Sbjct: 349 HASNIAGSDEGFAMVTV 365 Score = 71.3 bits (167), Expect = 2e-11 Identities = 56/202 (27%), Positives = 85/202 (42%), Gaps = 12/202 (5%) Query: 379 TEERIEISEKALAPQF-VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437 T E I + PQ V + V G+ C VTG P P + W + + R + Sbjct: 87 TAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVELLCTVTGYPVPSIEWIVPN---RTGLS 143 Query: 438 HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE-R 496 ++ G ++I NVT G C+A+N G +L V+ V P V + Sbjct: 144 PSLVKVAQGVLKIVIENVTSPYEGRYRCMAKNNLGTAEEVVQLFVV--PNVTRPNNVSVQ 201 Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556 V +G N A G PTP++ W++ G + PE + +D G T++ A Sbjct: 202 PVNQKVVKGNTATFNCTASGVPTPQLVWERLGAKM---PETAMTSDKGLLTIE--SVGAD 256 Query: 557 DAAWYQCTAQNVAGSTATRARL 578 D+ Y+C A N GS A+L Sbjct: 257 DSGEYECIATNSEGSERVLAKL 278 Score = 61.7 bits (143), Expect = 1e-08 Identities = 47/190 (24%), Positives = 78/190 (41%), Gaps = 7/190 (3%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKI-VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680 P I+P + VA G+ + F C + G P P + W + + I ++ + + L Sbjct: 5 PVVSIQPSPQQTVAGGETVVFRCAVNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVL 64 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740 +I+ AF D G Y C A N G A L V +A+ ++P R V G+ + Sbjct: 65 KIAHAFDSDSGRYACRATNLLGTAEAIAVLNV----KAEPQVTVSPSRQHYVATGRQVEL 120 Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 +T P+I+W+ +P + +G ++I N G + C A G Sbjct: 121 LCTVTGYPVPSIEWIVPNR-TGLSPSLVKVAQG-VLKIVIENVTSPYEGRYRCMAKNNLG 178 Query: 4801 QVETSAKLVV 4810 E +L V Sbjct: 179 TAEEVVQLFV 188 Score = 52.0 bits (119), Expect = 1e-05 Identities = 54/220 (24%), Positives = 85/220 (38%), Gaps = 20/220 (9%) Query: 353 LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ-DRDVTEGKMTRF 411 + +E+ T Y R + E ++ + P V V ++ V +G F Sbjct: 156 IVIENVTSPYEGRYRCMAKNNLGTAEEVVQLFVVPNVTRPNNVSVQPVNQKVVKGNTATF 215 Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471 +C +G P P++ W ++ + ++ G L I +V DSG C+A N Sbjct: 216 NCTASGVPTPQLVW----ERLGAKMPETAMTSDKG--LLTIESVGADDSGEYECIATNSE 269 Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531 G +L VI V P +++ G P L V P +TW K Sbjct: 270 GSERVLAKLEVI-----VPPDVAVSPQQVSINLGRPFRL--FCVSNPPLPLTWSKVN-GT 321 Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 I N + + GG L + A D Y+C A N+AGS Sbjct: 322 ISNSSVVV---GG--VLIVQEAIIQDTGKYRCHASNIAGS 356 Score = 49.2 bits (112), Expect = 8e-05 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPT-IQWLREGALIPETPDFQMIHEGNNAVLLIG 4781 ++ P V G+ F+ + + + P I W R+G I T D H VL I Sbjct: 8 SIQPSPQQTVAGGETVVFRCAVNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIA 67 Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + ++ D+G + CRAT G E A L VK++ Sbjct: 68 HAFDSDSGRYACRATNLLGTAEAIAVLNVKAE 99 Score = 46.8 bits (106), Expect = 4e-04 Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 1/116 (0%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 PV + + + G+ F C V P I W +GQ I T H Sbjct: 5 PVVSIQPSPQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNV 63 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224 L I + + DSG Y C+ATN LG A L V + + + + RQ+E Sbjct: 64 LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVE 119 Score = 46.4 bits (105), Expect = 6e-04 Identities = 50/183 (27%), Positives = 70/183 (38%), Gaps = 18/183 (9%) Query: 403 VTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461 V G+ F C V G P P +TW + + I + ++ GN L I + SDSG Sbjct: 17 VAGGETVVFRCAVNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGN-VLKIAHAFDSDSG 75 Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521 C A N G LNV + QV + + V G V L G P P Sbjct: 76 RYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHY----VATGRQVELLCTVTGYPVPS 131 Query: 522 ITWQKDGVPIIPN-----PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 I W I+PN P L + G + I + Y+C A+N G+ Sbjct: 132 IEW------IVPNRTGLSPSL-VKVAQGVLKIVIENVTSPYEGRYRCMAKNNLGTAEEVV 184 Query: 577 RLY 579 +L+ Sbjct: 185 QLF 187 Score = 45.6 bits (103), Expect = 0.001 Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 19/133 (14%) Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847 G+ + F C V P I W + +P+ + + H L I H ++ DSG Y Sbjct: 20 GETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYA 78 Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV--PD 2905 C+ATN G+A L + + V + + +A GR+ + Sbjct: 79 CRATNLLGTAEAIAVLNVKAEPQV--------------TVSPSRQHYVATGRQVELLCTV 124 Query: 2906 TEYPKP--EWIIP 2916 T YP P EWI+P Sbjct: 125 TGYPVPSIEWIVP 137 Score = 45.2 bits (102), Expect = 0.001 Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 4/120 (3%) Query: 3978 QIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGW 4037 Q Q ++ ET F C + G P + W +G+P+ + + + + Sbjct: 10 QPSPQQTVAGGETVVFRCAVN-AGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAH 68 Query: 4038 VYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVT 4097 + DSG Y CRATNL G E AV+ +P + P + R++E VT Sbjct: 69 AFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVS---PSRQHYVATGRQVELLCTVT 125 Score = 44.8 bits (101), Expect = 0.002 Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 1/103 (0%) Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G++ F C V P I W +GQP+ ++ T VL IA+ + DSG Y Sbjct: 20 GETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYA 78 Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESL 3266 CRA N G A +N + V + + +A R++E L Sbjct: 79 CRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVELL 121 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771 V P VA + F + G P + W R+G PI + +T H L Sbjct: 7 VSIQPSPQQTVAGGETVVFRCA-VNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLK 65 Query: 1772 MKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825 + + DSG Y CRA N LG A + L V+++ + + + + +Q+E Sbjct: 66 IAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVE 119 Score = 44.4 bits (100), Expect = 0.002 Identities = 40/150 (26%), Positives = 58/150 (38%), Gaps = 9/150 (6%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141 I W +G+ I + T + VL+I +DSG Y+CRATN G AE L Sbjct: 38 ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVL--- 94 Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201 + +P+ T + G+ CTV P IEW + + +K Sbjct: 95 --NVKAEPQVTVSPSRQHYVATGRQVELLCTVTGYPVP--SIEWIVPNRTGLSPSLVKVA 150 Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 G + + I + G Y C A N G Sbjct: 151 Q--GVLKIVIENVTSPYEGRYRCMAKNNLG 178 Score = 43.6 bits (98), Expect = 0.004 Identities = 24/89 (26%), Positives = 39/89 (43%) Query: 290 SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349 +G P P +TW ++GQ + N+ + L++ + SDSG Y A N G Sbjct: 31 AGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEA 90 Query: 350 SGYLAVESPTESYVQDQRSQYITDTQQRE 378 L V++ + V R Y+ +Q E Sbjct: 91 IAVLNVKAEPQVTVSPSRQHYVATGRQVE 119 Score = 43.2 bits (97), Expect = 0.005 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 3/107 (2%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 P I P T G + F + G P I W ++GQ I + ++ Sbjct: 5 PVVSIQPSPQQTVAGGETVVFRCAVN-AGMPPPFITWSRDGQPINNTQDNSTAHVIEGNV 63 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQH 740 L + DSG Y CRA + G AE AVL+V P+ T+ + QH Sbjct: 64 LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQH 110 Score = 43.2 bits (97), Expect = 0.005 Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 5/117 (4%) Query: 1178 VFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVAL 1237 V +QP S V+ G+ + C + G P + W +G+ + T + L Sbjct: 7 VSIQP-SPQQTVAGGETVVFRCAVNA-GMPPPFITWSRDGQPINNTQDNSTAHVIEGNVL 64 Query: 1238 DIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAI---EQIQLL 1291 I HA +D+G Y RA N LG+A A++ V + + + Q++LL Sbjct: 65 KIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVELL 121 Score = 43.2 bits (97), Expect = 0.005 Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 1/101 (0%) Query: 1449 RPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508 +P + V G+ V F C + + W ++GQP+ H L I Sbjct: 10 QPSPQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNVLKIAH 68 Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE 1549 DSG Y CRA NL+GT E L ++ + S + Sbjct: 69 AFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQ 109 Score = 43.2 bits (97), Expect = 0.005 Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 13/160 (8%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 TG IEW +T + ++ A G++ + I + G Y C A N G AE Sbjct: 125 TGYPVPSIEWIVPNRTGLSPSLVKV--AQGVLKIVIENVTSPYEGRYRCMAKNNLGTAEE 182 Query: 3135 SVKLECVDKSKGQKPRFTTHIQNI-EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193 V+L V +P +Q + + + G +A F CT V P ++ W G M Sbjct: 183 VVQLFVVPNV--TRPN-NVSVQPVNQKVVKGNTATFNCTASGVPTP--QLVWERLGAKMP 237 Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233 + SD G +L I DSGEY C A N G + Sbjct: 238 ETA---MTSDKG--LLTIESVGADDSGEYECIATNSEGSE 272 Score = 43.2 bits (97), Expect = 0.005 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 5/103 (4%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 P ++ +P N K+ +G A F SG P P++ W + G ++ E T + L Sbjct: 195 PNNVSVQPVNQKVVKGNTATFNCTASGVPTPQLVWERLGAKM-----PETAMTSDKGLLT 249 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367 + + DSG Y +A N G L V P + V Q+ Sbjct: 250 IESVGADDSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQQ 292 Score = 42.7 bits (96), Expect = 0.007 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 1/101 (0%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P +++ V G V F C V G P I W +G+P T + Sbjct: 5 PVVSIQPSPQQTVAGGETVVFRCAVN-AGMPPPFITWSRDGQPINNTQDNSTAHVIEGNV 63 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795 L I + + D+G Y CRATN G+A A + A+ + + Sbjct: 64 LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTV 104 Score = 42.7 bits (96), Expect = 0.007 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 6/104 (5%) Query: 3824 PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883 P+VS P TV E V F C V P I W R+G+ + + T + Sbjct: 5 PVVSIQPS-----PQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHV 58 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927 + L I + + DSG Y CRA N G A ++ K P + Sbjct: 59 IEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQV 102 Score = 42.3 bits (95), Expect = 0.009 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450 G+T F C + G P + W R+ + I ++ + H + I+H D D G Y Sbjct: 20 GETVVFRCA-VNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYA 78 Query: 2451 CRASNLLG 2458 CRA+NLLG Sbjct: 79 CRATNLLG 86 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P + W +DG+PI + ++ L I H D+G Y RA N LG A + A Sbjct: 34 PPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAV 93 Query: 860 IRVAARSTVTADLGIPEQRRYI 881 + V A VT P ++ Y+ Sbjct: 94 LNVKAEPQVTVS---PSRQHYV 112 Score = 40.7 bits (91), Expect = 0.028 Identities = 20/80 (25%), Positives = 35/80 (43%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 + W +G+P+ T + +L+I + D+G Y C+ATN G A L VK Sbjct: 38 ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVK 97 Query: 3651 GRQGIILEPQLPSHFKSGTE 3670 + + P + +G + Sbjct: 98 AEPQVTVSPSRQHYVATGRQ 117 Score = 40.3 bits (90), Expect = 0.037 Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 9/75 (12%) Query: 80 NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGP 138 N + +G A F G PTP + W R A + E T D LL I+ +G Sbjct: 204 NQKVVKGNTATFNCTASGVPTPQLVWERLGAKMPE--------TAMTSDKGLLTIESVGA 255 Query: 139 GDEGEYTCTARNQYG 153 D GEY C A N G Sbjct: 256 DDSGEYECIATNSEG 270 Score = 39.5 bits (88), Expect = 0.065 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG--EAVTT 2064 P + W +G+P+ T + L I +A+ D+G Y C+ATN +G EA+ Sbjct: 34 PPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAV 93 Query: 2065 SSVKVD 2070 +VK + Sbjct: 94 LNVKAE 99 Score = 39.1 bits (87), Expect = 0.086 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 7/95 (7%) Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763 N V +G F+C G PT ++ W G A +D G L I+ + A Sbjct: 204 NQKVVKGNTATFNCTAS--GVPTPQLVWERLG---AKMPETAMTSDKGL--LTIESVGAD 256 Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798 D+GEY C ATN GS AK+ D+ + Q Sbjct: 257 DSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQ 291 Score = 38.3 bits (85), Expect = 0.15 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918 G++ + C + P + W +G+ + + T++ L I + DSG Y Sbjct: 20 GETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYA 78 Query: 1919 CKAINNLGQAVSSIRLNVQSKESI 1942 C+A N LG A + LNV+++ + Sbjct: 79 CRATNLLGTAEAIAVLNVKAEPQV 102 Score = 38.3 bits (85), Expect = 0.15 Identities = 20/62 (32%), Positives = 29/62 (46%) Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 + W +G+PI A+ + L + + DSG Y C+ATN LG A L V Sbjct: 38 ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVK 97 Query: 1404 AK 1405 A+ Sbjct: 98 AE 99 Score = 38.3 bits (85), Expect = 0.15 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 9/98 (9%) Query: 3277 PSAEPPKFITQIQDVT-KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH 3335 P+ P ++ +Q V K+V+G +A F V P L W G K+P Sbjct: 190 PNVTRPNNVS-VQPVNQKVVKGNTATFNCTASGVPTPQLV--WERLGAKMPET---AMTS 243 Query: 3336 DFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373 D G++ ++ + ++SGEYEC+ATN G + A L+ Sbjct: 244 DKGLLTIESVGA--DDSGEYECIATNSEGSERVLAKLE 279 Score = 37.1 bits (82), Expect = 0.35 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 7/109 (6%) Query: 3824 PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883 P V+ P Q + V + F C P+L W R G +P D Sbjct: 190 PNVTRPNNVSVQPVNQKVVKGNTATFNCTASGVPTPQL--VWERLGAKMPET---AMTSD 244 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932 G ++++ V A+DSGEY C A N G + A + PD+ + Q Sbjct: 245 KGLLTIES--VGADDSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQ 291 Score = 36.7 bits (81), Expect = 0.46 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 9/103 (8%) Query: 2356 LESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRN 2415 L +AE + + VTR V QP+ + +G TA F+C G PT ++ W Sbjct: 177 LGTAEEVVQLFVVPNVTRPNNVSVQPVNQ--KVVKGNTATFNCTAS--GVPTPQLVW--- 229 Query: 2416 EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 E+L T D G +TI V +D G Y C A+N G Sbjct: 230 ERLGAKMPETAMTSDKGL--LTIESVGADDSGEYECIATNSEG 270 Score = 36.3 bits (80), Expect = 0.61 Identities = 35/165 (21%), Positives = 67/165 (40%), Gaps = 5/165 (3%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 PV ++ S + + GE F + P + W +G+ + T + Sbjct: 5 PVVSIQPSPQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNV 63 Query: 3480 LEISPTYPEDSGEYLCRAYNNYG--EAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537 L+I+ + DSG Y CRA N G EA+ ++K + + + Q ++ + Sbjct: 64 LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVELLCT 123 Query: 3538 LEGYS-GTVDTLTPEAESGNPPEFTTTPSDL-ILSENSSAHFECR 3580 + GY +++ + P +P L I+ EN ++ +E R Sbjct: 124 VTGYPVPSIEWIVPNRTGLSPSLVKVAQGVLKIVIENVTSPYEGR 168 Score = 35.9 bits (79), Expect = 0.80 Identities = 18/65 (27%), Positives = 29/65 (44%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 + W +DG+P+ + +T L I D+G Y CRA N +G A A L + Sbjct: 38 ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVK 97 Query: 1003 TKKDI 1007 + + Sbjct: 98 AEPQV 102 Score = 35.5 bits (78), Expect = 1.1 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 18/130 (13%) Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 G++ +E +G DSG Y C ATN G + KLE + P Q + + Sbjct: 246 GLLTIESVGAD--DSGEYECIATNSEGSERVLAKLEVI-----VPPDVAVSPQQV-SINL 297 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G+ C V +P + + W + +S +V G +++ A Q D+G+Y Sbjct: 298 GRPFRLFC----VSNPPLPLTWSKVNGTISNS----SVVVGGVLIVQEAIIQ--DTGKYR 347 Query: 3224 CRAYNKYGED 3233 C A N G D Sbjct: 348 CHASNIAGSD 357 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 3/96 (3%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P+ + + G+ V V P I W ++G + + Sbjct: 5 PVVSIQPSPQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNV 63 Query: 2702 LSINSLRNDDSGIYTCKATNLLG--EAVSTASIKIE 2735 L I + DSG Y C+ATNLLG EA++ ++K E Sbjct: 64 LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAE 99 Score = 34.3 bits (75), Expect = 2.5 Identities = 16/44 (36%), Positives = 22/44 (50%) Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012 LTI+SV D+G Y C A N+ G A L ++ D+ Q Sbjct: 248 LTIESVGADDSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQ 291 Score = 32.7 bits (71), Expect = 7.5 Identities = 18/82 (21%), Positives = 33/82 (40%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 + W + +P+ + + + L I DSG Y CRA N LG A + V Sbjct: 38 ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVK 97 Query: 1671 SKKSIYLESQHEGALPRLNQLE 1692 ++ + + + + Q+E Sbjct: 98 AEPQVTVSPSRQHYVATGRQVE 119 Score = 32.7 bits (71), Expect = 7.5 Identities = 15/49 (30%), Positives = 25/49 (51%) Query: 3316 VEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364 + W +G+ + + T H +L I + ++ +SG Y C ATN LG Sbjct: 38 ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLG 86 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 9/118 (7%) Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222 V ++ + +++ V VQP++ V +G C G PT ++ W G + Sbjct: 183 VVQLFVVPNVTRPNNVSVQPVNQK--VVKGNTATFNCTAS--GVPTPQLVWERLGAKMPE 238 Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280 + D G + ++ + A D+GEY A N GS A + VI D+ Q Sbjct: 239 TAMTS---DKGLLTIESVGAD--DSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQ 291 >SB_10606| Best HMM Match : I-set (HMM E-Value=0) Length = 872 Score = 100 bits (239), Expect = 3e-20 Identities = 107/399 (26%), Positives = 164/399 (41%), Gaps = 45/399 (11%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT--AK 4493 G P P I W REN + PD I S L + DSA +A E+ G A Sbjct: 365 GVPRPKIIWLRENEVVY--PDDVIELGCNGS-LRFHGIRTRDSAEYACYVESYLGMDMAF 421 Query: 4494 CSANLVVEEKRRQGR-----GGIVPPSFT-----LTAQNVNVTSGQLVRLDTKVTGTKPI 4543 S N+V+ + R+ + +P S T + + NV V +R+ TG Sbjct: 422 TSVNVVLSLEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP 481 Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603 V W +NG + R ++ DG T+LI A D+G + C A N AG+ + + +V Sbjct: 482 RVTWRQNGNAISQGGRYRVTA-DGV-TMLIDGAVVSDTGSFTCEAENFAGKDKATSAVIV 539 Query: 4604 SLPA-----TKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWY 4657 +PA +KP+P + +P I + D I A + F C G P+P+V W Sbjct: 540 KIPAKPSIERTNKPRPISPEDGSP--ITITIGDNITALTNTQVTFRCNATGTPMPSVIWT 597 Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL------- 4710 K +++ +++ + ++ I +A P D G Y C A NS G V++ L Sbjct: 598 KDGQVLVSGPRHVINK---DGSIVIQKASPVDRGRYTCTARNSHGEDRVSSTLNTMDPVV 654 Query: 4711 -KVTQPDQADNLPALTPLR-------DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 K+ PD + R +I +T PTI W R G +P Sbjct: 655 PKILSPDDPRTIHPDHRSRVHGTIGDNITALTDTLVTLHCPVTGVPAPTITWSRNGQEMP 714 Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 D ++ NN L++ D G +TC A A G+ Sbjct: 715 ANGDGYLV--TNNGSLILEKVSSSDIGRYTCTARNAFGK 751 Score = 86.6 bits (205), Expect = 4e-16 Identities = 80/304 (26%), Positives = 128/304 (42%), Gaps = 43/304 (14%) Query: 285 FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPN 344 F+ +G P P V W K+GQ L++ +H I + ++ ++ D G YT A N + Sbjct: 582 FRCNATGTPMPSVIWTKDGQVLVSGPRHVI---NKDGSIVIQKASPVDRGRYTCTARNSH 638 Query: 345 GCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVT 404 G S L P + D + + R + + D VT Sbjct: 639 GEDRVSSTLNTMDPVVPKILSP-----DDPRTIHPDHRSRVH--GTIGDNITALTDTLVT 691 Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464 C VTG P P +TW N +++ + + ++ N N +L++ V+ SD G T Sbjct: 692 ------LHCPVTGVPAPTITWSRNGQEMPANGDGYLVTN---NGSLILEKVSSSDIGRYT 742 Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFV--ERFSTLNVREGEP--------------- 507 C ARN G+ +NV++ V+P+ V + T+ +G P Sbjct: 743 CTARNAFGKDNANSTVNVMDP---VSPEIVRSDEPRTIPPGDGSPLTATVGDNITALTNT 799 Query: 508 -VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566 V L +A GTP P + W KDG ++ P I+ +G ++ I +A D Y CTA+ Sbjct: 800 QVTLRCQATGTPMPSVIWSKDGQVLVSGPRHVINKNG---SIVIQKASPVDRGRYTCTAR 856 Query: 567 NVAG 570 N G Sbjct: 857 NSHG 860 Score = 85.4 bits (202), Expect = 1e-15 Identities = 98/403 (24%), Positives = 157/403 (38%), Gaps = 41/403 (10%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P PL+ W + PI + ++ T S++I+ DS + A N G Sbjct: 256 GSPKPLVDWSKTGQPIISGD--RVSVTVTGSLVIVNSRS-SDSGEYVCTARNLLGEDSAV 312 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTSGQLVRL--DTKVTGTKPID------VY 4546 + + + R G L + VNVT+GQ V + DT + PI + Sbjct: 313 STVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKGVPRPKII 372 Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE--ARCDAECVVS 4604 WL+ + V PD ++E +L +DS +Y C + G A V+S Sbjct: 373 WLRENEVVYPD---DVIELGCNGSLRFHGIRTRDSAEYACYVESYLGMDMAFTSVNVVLS 429 Query: 4605 LPATKDK---PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGD 4660 L K K P P T + P + + D + V E I C G P P V W + Sbjct: 430 LEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNG 489 Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR--------VTVAAKLKV 4712 I +++ TAD T+ I A D G + C A N AG+ V + AK + Sbjct: 490 NAISQGGRYRV--TADGVTMLIDGAVVSDTGSFTCEAENFAGKDKATSAVIVKIPAKPSI 547 Query: 4713 TQPDQA------DNLPALTPLRD-IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765 + ++ D P + D I F+ T P++ W ++G ++ P Sbjct: 548 ERTNKPRPISPEDGSPITITIGDNITALTNTQVTFRCNATGTPMPSVIWTKDGQVLVSGP 607 Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 + +G+ ++I D G +TC A + G+ S+ L Sbjct: 608 RHVINKDGS---IVIQKASPVDRGRYTCTARNSHGEDRVSSTL 647 Score = 84.6 bits (200), Expect = 2e-15 Identities = 94/411 (22%), Positives = 165/411 (40%), Gaps = 43/411 (10%) Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481 V E R G P P + W + I +++ T ++LI V V D+ F Sbjct: 463 VLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRV-TADGVTMLIDGAV-VSDTGSF 520 Query: 4482 AAVAENRGGTAKCSANLVVE-----EKRRQGRGGIVPPS----FTLT-AQNVNVTSGQLV 4531 AEN G K ++ ++V+ R + + P T+T N+ + V Sbjct: 521 TCEAENFAGKDKATSAVIVKIPAKPSIERTNKPRPISPEDGSPITITIGDNITALTNTQV 580 Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591 TGT V W K+G+ + R+ ++ +DG+ ++I +A P D G+Y C A NS Sbjct: 581 TFRCNATGTPMPSVIWTKDGQVLVSGPRH-VINKDGS--IVIQKASPVDRGRYTCTARNS 637 Query: 4592 AGEARCDAECVVS---LPATKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIV 4647 GE R + +P P+T + + + D I A + C + Sbjct: 638 HGEDRVSSTLNTMDPVVPKILSPDDPRTIHPDHRSRVHGTIGDNITALTDTLVTLHCPVT 697 Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 G P PT+ W + G ++ + ++ ++S + D G Y C A N+ G+ Sbjct: 698 GVPAPTITWSRNGQEMPANGDGYLVTNNGSLILEKVSSS---DIGRYTCTARNAFGKDNA 754 Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQP----------AQFKTQITSKIK------P 4750 + + V P + + + P R I +G P A TQ+T + + P Sbjct: 755 NSTVNVMDPVSPEIVRSDEP-RTIPPGDGSPLTATVGDNITALTNTQVTLRCQATGTPMP 813 Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 ++ W ++G ++ P + N ++I D G +TC A + G+ Sbjct: 814 SVIWSKDGQVLVSGPRHVI---NKNGSIVIQKASPVDRGRYTCTARNSHGE 861 Score = 83.8 bits (198), Expect = 3e-15 Identities = 74/312 (23%), Positives = 132/312 (42%), Gaps = 36/312 (11%) Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N + E + + +G P PRVTW +NG + ++ + T + T+ + SD+ Sbjct: 460 NVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRV--TADGVTMLIDGAVVSDT 517 Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393 G +T AEN G + + V+ P + ++ T + IS + +P Sbjct: 518 GSFTCEAENFAGKDKATSAVIVKIPAKPSIE-------------RTNKPRPISPEDGSPI 564 Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453 + + + F C TG P P V W + + + H ++N+ G +++I Sbjct: 565 TITIGDNITALTNTQVTFRCNATGTPMPSVIWTKDGQVLVSGPRH--VINKDG--SIVIQ 620 Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIEK--EQVVAPK-----FVERFSTLNVREGE 506 + D G TC ARN GE LN ++ ++++P + S ++ G+ Sbjct: 621 KASPVDRGRYTCTARNSHGEDRVSSTLNTMDPVVPKILSPDDPRTIHPDHRSRVHGTIGD 680 Query: 507 P--------VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558 V L+ G P P ITW ++G + N + + T+ G+ L+ + +SD Sbjct: 681 NITALTDTLVTLHCPVTGVPAPTITWSRNGQEMPANGDGYLVTNNGSLILE--KVSSSDI 738 Query: 559 AWYQCTAQNVAG 570 Y CTA+N G Sbjct: 739 GRYTCTARNAFG 750 Score = 78.2 bits (184), Expect = 2e-13 Identities = 77/307 (25%), Positives = 124/307 (40%), Gaps = 48/307 (15%) Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338 EG + + G P P +TW G+ L SN + I+ + NT+ SD+G Y Sbjct: 34 EGTSVSIKCPVQGIPAPAITWSNGGRFLPVSNGNSILV--------LSNTRVSDTGEYMC 85 Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQ-RSQYITDTQQRETEERIEISEKALAPQFVKV 397 A +P G S L V +P + + + I T+ + I S A Sbjct: 86 TAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTKAVSVNIRDSVTAFL------ 139 Query: 398 CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457 G R C G P PEV W + +++ D V+E+G ++++ T Sbjct: 140 --------GSTLRIRCSANGLPAPEVKWSKDGQRVVKD------VDENGTLSIVLRRTT- 184 Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKE--QVVAPKFV------------ERFSTLNVR 503 D+G C A N G + + V+E ++VA K + + T+ Sbjct: 185 -DAGRYVCTAVNAIGSDEAETFVYVVEPNYPRIVAKKGLATALDGRRPIAGQIGMTIRTL 243 Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563 + L G+P P + W K G PII + + G +L I +++SD+ Y C Sbjct: 244 TSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTVTG---SLVIVNSRSSDSGEYVC 300 Query: 564 TAQNVAG 570 TA+N+ G Sbjct: 301 TARNLLG 307 Score = 77.0 bits (181), Expect = 4e-13 Identities = 73/345 (21%), Positives = 133/345 (38%), Gaps = 23/345 (6%) Query: 4381 KITSTETTEIEHKAQTQERVVEGPVKPSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPL 4439 K TS +I K + P+ P PI + Q F G P+ Sbjct: 532 KATSAVIVKIPAKPSIERTNKPRPISPEDGSPITITIGDNITALTNTQVTFRCNATGTPM 591 Query: 4440 PLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL- 4498 P + W ++ + + P H + ++I++ D + A N G + S+ L Sbjct: 592 PSVIWTKDGQVLVSGPR---HVINKDGSIVIQKASPVDRGRYTCTARNSHGEDRVSSTLN 648 Query: 4499 ----VVEEKRRQGRGGIVPPSFT-----LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549 VV + + P N+ + LV L VTG + W + Sbjct: 649 TMDPVVPKILSPDDPRTIHPDHRSRVHGTIGDNITALTDTLVTLHCPVTGVPAPTITWSR 708 Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609 NG+++ + ++ +G+ L++ + D G+Y C A N+ G+ ++ V P + Sbjct: 709 NGQEMPANGDGYLVTNNGS--LILEKVSSSDIGRYTCTARNAFGKDNANSTVNVMDPVSP 766 Query: 4610 D---KPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665 + +P+T + + D I A + C+ G P+P+V W K +++ Sbjct: 767 EIVRSDEPRTIPPGDGSPLTATVGDNITALTNTQVTLRCQATGTPMPSVIWSKDGQVLVS 826 Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710 +++ ++ I +A P D G Y C A NS G V + L Sbjct: 827 GPRHVINKNG---SIVIQKASPVDRGRYTCTARNSHGEDRVLSTL 868 Score = 74.5 bits (175), Expect = 2e-12 Identities = 126/502 (25%), Positives = 191/502 (38%), Gaps = 84/502 (16%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 P T+ +S +N+ E++ T P +V W NG ++ G R+R D G + Sbjct: 451 PRVTIVIS--DNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTAD-GVTM 507 Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539 L I D+G + C A N G+ T+++ V KI A Sbjct: 508 L-IDGAVVSDTGSFTCEAENFAGKDKATSAVIV---------------------KIPAKP 545 Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILS-ENSSAHFECRLIPVNDSSMRVEWFHNGK 3598 T E G+P T T D I + N+ F C S V W +G+ Sbjct: 546 SIERTNKPRPISPEDGSP--ITITIGDNITALTNTQVTFRCNATGTPMPS--VIWTKDGQ 601 Query: 3599 PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILE 3658 L++G R IN G ++++ R G YTC A N HGE VS L ++ Sbjct: 602 VLVSGPR-HVINKDGSIVIQKASPVDR--GRYTCTARNSHGEDRVSSTLNT-------MD 651 Query: 3659 PQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCR 3718 P +P + L + TI + + R I DNI V C Sbjct: 652 PVVP--------------KILSPDDPRTIHPD--HRSRVHGTIGDNITALTDTLVTLHCP 695 Query: 3719 VEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778 V V PT I W NG+ + + + G +L ++ + + D G YTC A N +G Sbjct: 696 VTGVPAPT--ITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGK 751 Query: 3779 ATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKS 3838 + + V++ P E+ R SD P+ P P T + Sbjct: 752 DNANSTVN-------VMDPVSP---------EIVR---SDEPRTIPPGDGSPLTATVGDN 792 Query: 3839 HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAED 3898 T + V C+ P + W ++G++L SG R+ + G S+ I D Sbjct: 793 ITALTNTQVTLRCQATGTPMPS--VIWSKDGQVLVSGPRH-VINKNG--SIVIQKASPVD 847 Query: 3899 SGEYICRAVNDFGEDFTKATIS 3920 G Y C A N GED +T++ Sbjct: 848 RGRYTCTARNSHGEDRVLSTLN 869 Score = 73.3 bits (172), Expect = 4e-12 Identities = 100/422 (23%), Positives = 161/422 (38%), Gaps = 54/422 (12%) Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 + P+ T V E + G P P I W N F + + SIL Sbjct: 19 RKPVSTTIGSRVTVLEGTSVSIKCPVQGIPAPAITW-------SNGGRF-LPVSNGNSIL 70 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG-IVPPSFTLT---AQNVN 4524 ++ V D+ + A + G S L V ++ G +V LT A +VN Sbjct: 71 VLSNTRVSDTGEYMCTAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTKAVSVN 130 Query: 4525 VTS------GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP 4578 + G +R+ G +V W K+G++V D+ +E+GT ++++ Sbjct: 131 IRDSVTAFLGSTLRIRCSANGLPAPEVKWSKDGQRVVKDV-----DENGTLSIVLRRT-- 183 Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP-EIIEPLKDKI---- 4633 D+G+Y C A+N+ G + V P + P+ K A + P+ +I Sbjct: 184 TDAGRYVCTAVNAIGSDEAETFVYVVEP---NYPRIVAKKGLATALDGRRPIAGQIGMTI 240 Query: 4634 -VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692 +I C + G P P V W K + I ++ T +L I + D G+ Sbjct: 241 RTLTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTVTG---SLVIVNSRSSDSGE 297 Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQA------DNLPALTPLRDIVVYEGQ----PAQFKT 4742 Y C A N G + + + + P + ++ AL + V GQ PA T Sbjct: 298 YVCTARNLLGEDSAVSTVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTST 357 Query: 4743 QITSKIK----PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798 I+ IK P I WLRE ++ PD +I G N L D+ + C + Sbjct: 358 VISCPIKGVPRPKIIWLRENEVV--YPD-DVIELGCNGSLRFHGIRTRDSAEYACYVESY 414 Query: 4799 AG 4800 G Sbjct: 415 LG 416 Score = 73.3 bits (172), Expect = 4e-12 Identities = 161/715 (22%), Positives = 259/715 (36%), Gaps = 121/715 (16%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 TG +++W G+ I + R+ +V G +V I+ ++++DSG Y C A N G+ Sbjct: 255 TGSPKPLVDWSKTGQPIISGDRV-SVTVTGSLV--IVNSRSSDSGEYVCTARNLLGEDSA 311 Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD-----------PDMKI 3183 + ++ + HI + G + VP D P KI Sbjct: 312 VSTVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKGVPRPKI 371 Query: 3184 EWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243 W + + I+ + I + DS EY C + G D ++N Sbjct: 372 IWLRENEVVYPDDVIELGCNGSLRFHGI---RTRDSAEYACYVESYLGMDMAFTSVNVV- 427 Query: 3244 KGGVYLESLQPDSLAKIRELESLQGAQQQTPST-PSAEPPKFITQIQDVTKLVEGQSAHF 3302 + LE +P LA +P T P + P+ I D ++E + Sbjct: 428 ---LSLEPRKPKILAP-------------SPLTIPLSGTPRVTIVISDNVTVLEDSTIRI 471 Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362 + P +V W NG + G RYR D G+ +L I ++G + C A N Sbjct: 472 VCNATGLPAP--RVTWRQNGNAISQGGRYRVTAD-GVTML-IDGAVVSDTGSFTCEAENF 527 Query: 3363 LGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVF 3422 G+D K TS +I+ ++P + +E+ K + E G Sbjct: 528 AGKD------KATSA--VIV--KIP--AKPSIER---------TNKPRPISPEDGSPITI 566 Query: 3423 TVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI 3482 T+ +N+ N R T P V W +G+ L +G R D VI + Sbjct: 567 TIG----DNITALTNTQVTFRCNATGTPMPSVIWTKDGQVLVSGPRHVINKDGSIVIQKA 622 Query: 3483 SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYS 3542 SP D G Y C A N++GE ++++ M+ + KI + + Sbjct: 623 SPV---DRGRYTCTARNSHGEDRVSSTLNT---------------MDPVVPKILSPD--- 661 Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT 3602 T+ P+ S T ++ ++ C + V + + W NG+ + Sbjct: 662 -DPRTIHPDHRS---RVHGTIGDNITALTDTLVTLHCPVTGV--PAPTITWSRNGQEMPA 715 Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662 + + G +ILE V D G YTC A N G+ + + V ++P P Sbjct: 716 NGDGYLVTNNGSLILE--KVSSSDIGRYTCTARNAFGKDNANSTVNV-------MDPVSP 766 Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722 E + E TI +P T + DNI V C + Sbjct: 767 --------------EIVRSDEPRTIPPGDGSP--LTATVGDNITALTNTQVTLRC--QAT 808 Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG 3777 G P + W +G+ +G R H +N G I I D G YTC A N G Sbjct: 809 GTPMPSVIWSKDGQVLVSGPR-HVINKNGSIV--IQKASPVDRGRYTCTARNSHG 860 Score = 70.1 bits (164), Expect = 4e-11 Identities = 92/413 (22%), Positives = 153/413 (37%), Gaps = 46/413 (11%) Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488 R +G P P +KW ++ + D T SI++ R D+ + A N Sbjct: 144 RIRCSANGLPAPEVKWSKDGQRVVKDVDEN----GTLSIVLRRTT---DAGRYVCTAVNA 196 Query: 4489 GGTAKCSANLVVEEK---RRQGRGGIVP------PSFTLTAQNVNVTSGQLVRLDTKVTG 4539 G+ + + V E R + G+ P + + + L VTG Sbjct: 197 IGSDEAETFVYVVEPNYPRIVAKKGLATALDGRRPIAGQIGMTIRTLTSTSITLKCPVTG 256 Query: 4540 T-KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598 + KP+ V W K G QP I + T +L+I+ + DSG+Y C A N GE Sbjct: 257 SPKPL-VDWSKTG---QPIISGDRVSVTVTGSLVIVNSRSSDSGEYVCTARNLLGEDSAV 312 Query: 4599 AECVVSLPATKDKPKPQTKAANAP---PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655 + + P P P + +D V + SC I G P P + Sbjct: 313 STVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKGVPRPKII 372 Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR------VTVAAK 4709 W + ++++ P ++ +LR D +Y C + G V V Sbjct: 373 WLRENEVVYPDDVIELGCNG---SLRFHGIRTRDSAEYACYVESYLGMDMAFTSVNVVLS 429 Query: 4710 LKVTQPDQADNLPALTPLR-----------DIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758 L+ +P P PL ++ V E + T P + W + G Sbjct: 430 LEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNG 489 Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 I + +++ +G +LI DTG+FTC A AG+ + ++ ++VK Sbjct: 490 NAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGKDKATSAVIVK 540 Score = 69.3 bits (162), Expect = 7e-11 Identities = 72/306 (23%), Positives = 120/306 (39%), Gaps = 37/306 (12%) Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348 + G PRP++ W + + + ++I + +LR + DS Y E+ G + Sbjct: 363 IKGVPRPKIIWLRENEVVYPD---DVIELGCNGSLRFHGIRTRDSAEYACYVESYLG--M 417 Query: 349 TSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDR-DVTEGK 407 + +V ++ ++ + + + I +S P+ V D V E Sbjct: 418 DMAFTSVNVVLS--LEPRKPKILAPSPLT-----IPLSG---TPRVTIVISDNVTVLEDS 467 Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467 R C TG P P VTW N I +++ + ++I +SD+G TC A Sbjct: 468 TIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTAD---GVTMLIDGAVVSDTGSFTCEA 524 Query: 468 RNKSGETAFQCRLNV-------IEKEQVVAPKFVERFSTLNVREGE--------PVVLNA 512 N +G+ + V IE+ P E S + + G+ V Sbjct: 525 ENFAGKDKATSAVIVKIPAKPSIERTNKPRPISPEDGSPITITIGDNITALTNTQVTFRC 584 Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572 A GTP P + W KDG ++ P I+ DG ++ I +A D Y CTA+N G Sbjct: 585 NATGTPMPSVIWTKDGQVLVSGPRHVINKDG---SIVIQKASPVDRGRYTCTARNSHGED 641 Query: 573 ATRARL 578 + L Sbjct: 642 RVSSTL 647 Score = 68.5 bits (160), Expect = 1e-10 Identities = 115/490 (23%), Positives = 171/490 (34%), Gaps = 95/490 (19%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 PR T+ I DN+ V E + C G P R+ W NG + G R D + Sbjct: 451 PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYRVTADG--VT 506 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814 + ID D G +TC A N G T+ + IV ++P S I+ + Sbjct: 507 MLIDGAVVSDTGSFTCEAENFAGKDKATSAV-------IV---KIPAKPS---IERTNKP 553 Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874 R PI T IT + + V F C P + W ++G++L S Sbjct: 554 RPISPEDGSPITITIGDNITALTNTQVT------FRCNATGTPMPS--VIWTKDGQVLVS 605 Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVP 3934 G R+ D V I D G Y C A N GED Sbjct: 606 GPRHVINKDGSIV---IQKASPVDRGRYTCTARNSHGED--------------------- 641 Query: 3935 RGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFE 3994 + S L M+ + K L+ DD + R I + + Sbjct: 642 ---RVSSTLNTMDPVVPKI-----LSPDDPRTIHPDHRSRVHGTIGDNITALTDTLVTLH 693 Query: 3995 CQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPE-----DSGEYLCR 4049 C + V P + W NG+ + P GY+ N G + E D G Y C Sbjct: 694 CPVTGVPAPT--ITWSRNGQEM-------PANGDGYLVTNNGSLILEKVSSSDIGRYTCT 744 Query: 4050 ATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARC 4109 A N +G D + + V D P+ ++S E P + + Sbjct: 745 ARNAFGKDNANSTVN-------VMDPVSPEIVRSDE------------PRTIPPGDGS-- 783 Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDI 4169 P+ ++ D +T C+ TG P P V+W +G +V+G R+ + +G I Sbjct: 784 -PLTATVGDNITALTNTQVTLRCQATGTPMPSVIWSKDGQVLVSGPRHVINKNG--SIVI 840 Query: 4170 PKTRQYDTGK 4179 K D G+ Sbjct: 841 QKASPVDRGR 850 Score = 68.1 bits (159), Expect = 2e-10 Identities = 174/723 (24%), Positives = 276/723 (38%), Gaps = 133/723 (18%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE-AVTSGIAIV 1669 V+W +P+ SG R + T V ++ S DSG Y C A N LGE + S + I+ Sbjct: 262 VDWSKTGQPIISGDRVSVTVTGSLVIVNSRS---SDSGEYVCTARNLLGEDSAVSTVNIL 318 Query: 1670 HS-KKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAA 1728 + + I+ H ALP + + T+ Q S + T V + P+K Sbjct: 319 NPVRPGIFASYGHINALPGFSPVNVTAG-QDVSVPADTST---VISCPIK---------- 364 Query: 1729 HFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAI 1788 G P+ ++ WLR + + + + G +L + DS Y C Sbjct: 365 ---------GVPRPKIIWLRENEVVYPDD-VIELGCNG--SLRFHGIRTRDSAEYACYVE 412 Query: 1789 NELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFIT 1848 + LG + F L LE + L + + ++ PR Sbjct: 413 SYLGMDMA----FTSVNVVLSLEPRKPKILAP-------------SPLTIPLSGTPRVTI 455 Query: 1849 QLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILT 1908 ++ + E + C P P RV W NG + G RYR + D +D Sbjct: 456 VISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTADGVTMLIDGAV 513 Query: 1909 VYGEDSGEYTCKAINNLG--QAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKR 1966 V D+G +TC+A N G +A S++ + + +K SI R ++ ED S Sbjct: 514 V--SDTGSFTCEAENFAGKDKATSAVIVKIPAKPSIERTNKPRPISP-----EDGSPITI 566 Query: 1967 AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF 2026 + D+ + N +VT AT TP+ P+ V W +G+ + G R Sbjct: 567 TIGDNI---------TALTNTQVT----FRCNATGTPM--PS--VIWTKDGQVLVSGPRH 609 Query: 2027 KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLK 2086 D V I A D G Y C A N+ GE +S+ L+T+D Sbjct: 610 VINKDGSIV---IQKASPVDRGRYTCTARNSHGEDRVSST----------LNTMD----P 652 Query: 2087 KIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWF 2146 + ++ + P+ I + + V T ++ L + C V + P TI W Sbjct: 653 VVPKILSPDDPRTIHPDHRSR--VHGTIGDNITALTD-TLVTLHCPVTGVPAP--TITWS 707 Query: 2147 HNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR 2205 NGQ++ A G Y T++ G + L+ + D G Y C A N G+ + Sbjct: 708 RNGQEMPANGDGYLVTNN-GSLILE--KVSSSDIGRYTCTARNAFGK----------DNA 754 Query: 2206 NIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQ 2265 N ++ P E +R +EP+ PP + L T V + TA Q Sbjct: 755 NSTVNVMDPVSPEIVRS------------DEPRTIPPGDGSPLTAT--VGDNITALTNTQ 800 Query: 2266 V----EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAIN 2321 V + P + + +G+ L S R H+ G S+ IQ P D G Y+ A N Sbjct: 801 VTLRCQATGTPMPSVIWSKDGQVLVSGPR-HVINKNG--SIVIQKASPVDRGRYTCTARN 857 Query: 2322 ALG 2324 + G Sbjct: 858 SHG 860 Score = 67.3 bits (157), Expect = 3e-10 Identities = 105/445 (23%), Positives = 173/445 (38%), Gaps = 68/445 (15%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG-EAFTSS 2999 P ++ W NG + QG R+++T+D VT+ + D+G +TC+A N G + TS+ Sbjct: 479 PAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGAVVSDTGSFTCEAENFAGKDKATSA 536 Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD 3059 + IERT P+ P+D + P T+ +I Sbjct: 537 VIVKIPAKPSIERTNKPRPI-------------------SPEDGS---PITITIGDNITA 574 Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119 ++ Q+ + + TG + W +G+ + + R + G +V++ D G Sbjct: 575 LTNTQVT-FRCN--ATGTPMPSVIWTKDGQVLVSGPR-HVINKDGSIVIQ--KASPVDRG 628 Query: 3120 TYSCRATNKWGQAEISVKLECVDK-----SKGQKPR--FTTHIQNIEG-LKDGQSAHFEC 3171 Y+C A N G+ +S L +D PR H + G + D +A + Sbjct: 629 RYTCTARNSHGEDRVSSTLNTMDPVVPKILSPDDPRTIHPDHRSRVHGTIGDNITALTDT 688 Query: 3172 TVV---PVDD-PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 V PV P I W NGQ M + V++ G ++L+ + D G Y C A Sbjct: 689 LVTLHCPVTGVPAPTITWSRNGQEMPANGDGYLVTNNGSLILE--KVSSSDIGRYTCTAR 746 Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287 N +G+D +T+N ++ + P E ++ + +T P P T Sbjct: 747 NAFGKDNANSTVN-------VMDPVSP---------EIVRSDEPRT-IPPGDGSPLTATV 789 Query: 3288 IQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYC 3347 ++T L Q R P V W +G+ L G R+ + IVI Sbjct: 790 GDNITALTNTQ---VTLRCQATGTPMPSVIWSKDGQVLVSGPRHVINKNGSIVIQK---A 843 Query: 3348 YEENSGEYECVATNKLGRDSTKANL 3372 + G Y C A N G D + L Sbjct: 844 SPVDRGRYTCTARNSHGEDRVLSTL 868 Score = 65.3 bits (152), Expect = 1e-09 Identities = 71/305 (23%), Positives = 124/305 (40%), Gaps = 42/305 (13%) Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339 G+ + + +G P P V W K+GQR++ + TL + + +D+G Y Sbjct: 140 GSTLRIRCSANGLPAPEVKWSKDGQRVVKD-------VDENGTLSIVLRRTTDAGRYVCT 192 Query: 340 AENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ 399 A N G ++ V P + ++ +R +I ++ + L Sbjct: 193 AVNAIGSDEAETFVYVVEPNYPRIVAKKGLATALDGRRPIAGQIGMTIRTL--------- 243 Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 T +T C VTG P P V W + I ++ V +G+ L+I N SD Sbjct: 244 ----TSTSIT-LKCPVTGSPKPLVDWSKTGQPIIS--GDRVSVTVTGS--LVIVNSRSSD 294 Query: 460 SGVVTCVARNKSGETAFQCRLNVIE--KEQVVAP----KFVERFSTLNVREGEPV----- 508 SG C ARN GE + +N++ + + A + FS +NV G+ V Sbjct: 295 SGEYVCTARNLLGEDSAVSTVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPAD 354 Query: 509 ---VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 V++ G P P+I W ++ + P+ + + +G +L + D+A Y C Sbjct: 355 TSTVISCPIKGVPRPKIIWLRENEVVYPDDVIELGCNG---SLRFHGIRTRDSAEYACYV 411 Query: 566 QNVAG 570 ++ G Sbjct: 412 ESYLG 416 Score = 62.5 bits (145), Expect = 8e-09 Identities = 53/192 (27%), Positives = 80/192 (41%), Gaps = 31/192 (16%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V EG C V G P P +TW R L +GN L+++N +SD+G Sbjct: 32 VLEGTSVSIKCPVQGIPAPAITWSNGGR---------FLPVSNGNSILVLSNTRVSDTGE 82 Query: 463 VTCVARNKSGETAFQCRLNVI--EKEQV-------VAPKFVERFSTLNVRE------GEP 507 C A + G A L V+ +K + V P + ++N+R+ G Sbjct: 83 YMCTAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTKAVSVNIRDSVTAFLGST 142 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 + + A G P P + W KDG ++ + + +G TL I + +DA Y CTA N Sbjct: 143 LRIRCSANGLPAPEVKWSKDGQRVVKD----VDENG---TLSIVLRRTTDAGRYVCTAVN 195 Query: 568 VAGSTATRARLY 579 GS +Y Sbjct: 196 AIGSDEAETFVY 207 Score = 59.7 bits (138), Expect = 6e-08 Identities = 117/472 (24%), Positives = 177/472 (37%), Gaps = 77/472 (16%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P T V D V + E + TG + + W NG I R R V A G+ + Sbjct: 451 PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYR-VTADGVTM 507 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQ----AEISVKLECVDK-SKGQKPR---------FTT 3153 L I G +D+G+++C A N G+ + + VK+ + KPR T Sbjct: 508 L-IDGAVVSDTGSFTCEAENFAGKDKATSAVIVKIPAKPSIERTNKPRPISPEDGSPITI 566 Query: 3154 HI-QNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIA 3212 I NI L + Q F C P + W +GQ + R ++ G +V+ A Sbjct: 567 TIGDNITALTNTQVT-FRCNATGTPMPS--VIWTKDGQVLVSGPR-HVINKDGSIVIQKA 622 Query: 3213 YTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQ 3272 D G Y C A N +GED +T+N V + L PD I + + Sbjct: 623 SPV--DRGRYTCTARNSHGEDRVSSTLNTMDP--VVPKILSPDDPRTIH-----PDHRSR 673 Query: 3273 TPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLP-HGHRY 3331 T IT + D LV + H VP + W NG+++P +G Y Sbjct: 674 VHGTIGDN----ITALTDT--LV---TLHCPVTGVPAP----TITWSRNGQEMPANGDGY 720 Query: 3332 RTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGME 3391 ++ G +IL+ + + G Y C A N G+D+ + + ++D P Sbjct: 721 LVTNN-GSLILEKV--SSSDIGRYTCTARNAFGKDNANSTVN-------VMDPVSPE--- 767 Query: 3392 GGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPN 3451 + R D G T + +N+ N R T P Sbjct: 768 -------------IVRSDEPRTIPPGDGSPLTATVG--DNITALTNTQVTLRCQATGTPM 812 Query: 3452 LKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGE 3503 V W +G+ L +G R + VI + SP D G Y C A N++GE Sbjct: 813 PSVIWSKDGQVLVSGPRHVINKNGSIVIQKASPV---DRGRYTCTARNSHGE 861 Score = 56.0 bits (129), Expect = 7e-07 Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 19/195 (9%) Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348 ++G P P +TW +NGQ + + ++T N+ +L + SD G YT A N G Sbjct: 696 VTGVPAPTITWSRNGQEMPANGDGYLVT--NNGSLILEKVSSSDIGRYTCTARNAFGKDN 753 Query: 349 TSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKM 408 + + V P + R E R I +P V + Sbjct: 754 ANSTVNVMDPVSPEIV------------RSDEPRT-IPPGDGSPLTATVGDNITALTNTQ 800 Query: 409 TRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468 C+ TG P P V W + + + H ++N++G+ ++I + D G TC AR Sbjct: 801 VTLRCQATGTPMPSVIWSKDGQVLVSGPRH--VINKNGS--IVIQKASPVDRGRYTCTAR 856 Query: 469 NKSGETAFQCRLNVI 483 N GE LN + Sbjct: 857 NSHGEDRVLSTLNTM 871 Score = 55.6 bits (128), Expect = 9e-07 Identities = 113/479 (23%), Positives = 173/479 (36%), Gaps = 75/479 (15%) Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242 +S+ V E I + C G P RV W NG +++ G R++ D V + I A Sbjct: 457 ISDNVTVLEDSTIRIVCNAT--GLPAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGA 512 Query: 1243 TSADTGEYTVRAVNHLG-SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQV 1301 +DTG +T A N G TSA++ I + T + I ED + T + Sbjct: 513 VVSDTGSFTCEAENFAGKDKATSAVIVKIPAKPSIERTNKPRPISP----EDGSPITITI 568 Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361 ++IT + TN + R G V W +G+ + +G R Sbjct: 569 GDNITAL-----------------TNTQVTFRCNATGTPMPSVIWTKDGQVLVSGPRHVI 611 Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421 + V + P D G YTC A N GE S L + ++ + P I Sbjct: 612 NKDGSIV---IQKASPVDRGRYTCTARNSHGEDRVSSTLNTM--DPVVPKILSPDDPRTI 666 Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481 + + SR T I +++T + V C + V + W Sbjct: 667 -HPDHRSRVHGT--IGDNIT--------------ALTDTLVTLHCPVTGVPAPT--ITWS 707 Query: 1482 KNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541 +NGQ + + + G + L+ + + D G YTC A N G D + ST + Sbjct: 708 RNGQEMPANGDGYLVTNNGSLILEKVS--SSDIGRYTCTARNAFGKDNAN------STVN 759 Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601 ++ E V D + +T T+L N ++ R Sbjct: 760 VMDPVSPEI------VRSDEPRTIPPGDGSPLTATVGDNITALTNTQVT--LRCQATGTP 811 Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 +P V W + + L SG R N V I P D G YTC A N+ GE Sbjct: 812 MP------SVIWSKDGQVLVSGPRHVINKNGSIV---IQKASPVDRGRYTCTARNSHGE 861 Score = 48.8 bits (111), Expect = 1e-04 Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 14/144 (9%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQ---KPRFTTHIQN---IEG- 3160 L I+ +TTD+G Y C A N G E + V+ + + K T + I G Sbjct: 176 LSIVLRRTTDAGRYVCTAVNAIGSDEAETFVYVVEPNYPRIVAKKGLATALDGRRPIAGQ 235 Query: 3161 ----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216 ++ S P ++W GQP+ R+ V+++ +++ Sbjct: 236 IGMTIRTLTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTVTGSLVIVN---SRS 292 Query: 3217 HDSGEYVCRAYNKYGEDFTRATIN 3240 DSGEYVC A N GED +T+N Sbjct: 293 SDSGEYVCTARNLLGEDSAVSTVN 316 Score = 47.2 bits (107), Expect = 3e-04 Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 5/87 (5%) Query: 68 EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127 E PI I N F G P P V WT+ LV ++ + Sbjct: 559 EDGSPITITIGDNITALTNTQVTFRCNATGTPMPSVIWTKDGQVLVSGPRHVINK----- 613 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGE 154 D S++I++ P D G YTCTARN +GE Sbjct: 614 DGSIVIQKASPVDRGRYTCTARNSHGE 640 Score = 46.8 bits (106), Expect = 4e-04 Identities = 49/191 (25%), Positives = 76/191 (39%), Gaps = 25/191 (13%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669 +V W N + G R+ T + + +D + D+G++TC A N G+ + IV Sbjct: 482 RVTWRQNGNAISQGGRYRVTADGVTMLID--GAVVSDTGSFTCEAENFAGKDKATSAVIV 539 Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729 +P +E T+K + S +D +P+ +I N Sbjct: 540 --------------KIPAKPSIERTNKPRPISPED----GSPITITIGDNITALTNTQVT 581 Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789 F R G P V W ++G + + R D V ++ +P D G YTC A N Sbjct: 582 F--RCNATGTPMPSVIWTKDGQVLVSGPRHVINKDGSIV---IQKASPVDRGRYTCTARN 636 Query: 1790 ELGEAVTSSTL 1800 GE SSTL Sbjct: 637 SHGEDRVSSTL 647 Score = 46.4 bits (105), Expect = 6e-04 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 5/83 (6%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 PI QI R + + + G+P P+V W++ P++ ++ S+ TG SL Sbjct: 231 PIAGQIGMTIRTLTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTV---TG--SL 285 Query: 132 LIKQIGPGDEGEYTCTARNQYGE 154 +I D GEY CTARN GE Sbjct: 286 VIVNSRSSDSGEYVCTARNLLGE 308 Score = 45.6 bits (103), Expect = 0.001 Identities = 65/255 (25%), Positives = 100/255 (39%), Gaps = 38/255 (14%) Query: 1976 EKPQFGKPIKNAEV----TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ------GHR 2025 +KP P+ + T+ V++ ++T T+R+ NG P + G R Sbjct: 106 QKPSISGPVVGRVIPLTKTKAVSVNIRDSVTAFLGSTLRIRCSANGLPAPEVKWSKDGQR 165 Query: 2026 FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL 2085 D L I+ D G Y+C A NA+G +A++ +Y+ + R+ Sbjct: 166 VVKDVDENGT-LSIVLRRTTDAGRYVCTAVNAIGSD--------EAETFVYVVEPNYPRI 216 Query: 2086 KKIQELEK-YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTID 2144 + L + +PI GQ + + LTS +C V P +D Sbjct: 217 VAKKGLATALDGRRPIA----GQIGMTIRTLTSTS-------ITLKCPVT--GSPKPLVD 263 Query: 2145 WFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE--AVNTCTLKVA 2202 W GQ I +G R T V I+ + + DSG Y+C A N LGE AV+T + Sbjct: 264 WSKTGQPIISGDRVSVTVTGSLV---IVNSRSSDSGEYVCTARNLLGEDSAVSTVNILNP 320 Query: 2203 GHRNIILDTQHPNGL 2217 I H N L Sbjct: 321 VRPGIFASYGHINAL 335 Score = 45.6 bits (103), Expect = 0.001 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%) Query: 3816 ISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875 ++ +P P+ TP I + TV E +R C P R+ W +NG + G Sbjct: 438 LAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQG 495 Query: 3876 HRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922 RYR D + +D V D+G + C A N G+D + + K Sbjct: 496 GRYRVTADGVTMLIDGAVV--SDTGSFTCEAENFAGKDKATSAVIVK 540 Score = 45.2 bits (102), Expect = 0.001 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 40/233 (17%) Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704 SVTA G + R G P +++W K+GQ + + G +S+ + Sbjct: 134 SVTAFLGSTLRI--RCSANGLPAPEVKWSKDGQRV-----VKDVDENGTLSIVLRRTT-- 184 Query: 705 DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEE 764 D+G Y C AV+A G S ET Y+ + +Y + ++ + Sbjct: 185 DAGRYVCTAVNAIG-------------------SDEAETFVYVVE-PNYPRIVAKKGLAT 224 Query: 765 QTSQRPQFIRPLQ-DLGELQEGRNAHFEAQLTPVS-DPTMRVEWYKDGRPITASSRITSI 822 R RP+ +G + PV+ P V+W K G+PI + R+ S+ Sbjct: 225 ALDGR----RPIAGQIGMTIRTLTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRV-SV 279 Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE--AISTASIRVAARSTVTADLG 873 G SL I++ R+ D+G Y A N LGE A+ST +I R + A G Sbjct: 280 TVTG--SLVIVNSRSSDSGEYVCTARNLLGEDSAVSTVNILNPVRPGIFASYG 330 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/63 (44%), Positives = 36/63 (57%), Gaps = 5/63 (7%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE--AVST 2729 P ++W K G + +G R+ T LV +NS R+ DSG Y C A NLLGE AVST Sbjct: 258 PKPLVDWSKTGQPIISGDRVSVTVTGSLVI--VNS-RSSDSGEYVCTARNLLGEDSAVST 314 Query: 2730 ASI 2732 +I Sbjct: 315 VNI 317 Score = 44.8 bits (101), Expect = 0.002 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Query: 66 PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125 PG+ SP + + N + G P P V W++ LV ++ + N Sbjct: 779 PGDGSP-LTATVGDNITALTNTQVTLRCQATGTPMPSVIWSKDGQVLVSGPRHVINKNG- 836 Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGE 154 S++I++ P D G YTCTARN +GE Sbjct: 837 ----SIVIQKASPVDRGRYTCTARNSHGE 861 Score = 44.0 bits (99), Expect = 0.003 Identities = 81/329 (24%), Positives = 123/329 (37%), Gaps = 48/329 (14%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595 G P+ R W NG + G R+R T D VT+ I+ V +D G + C+A N AG Sbjct: 477 GLPAPRVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAG----- 529 Query: 2596 XXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLV 2655 I+ +P S E+ NK + + G +PI T + L Sbjct: 530 --KDKATSAVIVKIPAKP-SIER-------TNKPRPISPEDG---SPITITIGDNITALT 576 Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 Q + + P + W K+G L +G R D +V I D G Y Sbjct: 577 NTQVTF---RCNATGTPMPSVIWTKDGQVLVSGPRHVINKDGSIV---IQKASPVDRGRY 630 Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXV 2775 TC A N GE ++++ D ++ + L PD I V Sbjct: 631 TCTARNSHGEDRVSSTLNTMDP--VVPKILSPDDPRTI--------------HPDHRSRV 674 Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLD 2834 + +NI + C V PT I W N + +P +G Y T++ S + Sbjct: 675 HGTIGDNITALTDTLVTLHCPVTGVPAPT--ITWSRNGQEMPANGDGYLVTNNGSLI--- 729 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 + D G YTC A N+ G + ++ Sbjct: 730 LEKVSSSDIGRYTCTARNAFGKDNANSTV 758 Score = 43.6 bits (98), Expect = 0.004 Identities = 57/222 (25%), Positives = 86/222 (38%), Gaps = 34/222 (15%) Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231 ++K+K V V + + G + + C G P V+W +G+ V K + Sbjct: 121 LTKTKAVSVN-IRDSVTAFLGSTLRIRCSAN--GLPAPEVKWSKDGQRVV-----KDVDE 172 Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL 1291 G L I+ + D G Y AVN +GS V V+E N I + L Sbjct: 173 NG--TLSIVLRRTTDAGRYVCTAVNAIGSDEAETFVYVVE--------PNYPRIVAKKGL 222 Query: 1292 EDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK 1351 A + + I + I T+ T++ L+C + G V+W G+ Sbjct: 223 ATALDGRRPIAGQIGM-----------TIRTLTSTSITLKCPV--TGSPKPLVDWSKTGQ 269 Query: 1352 PIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393 PI +G R V ++ S DSG Y C A N LGE Sbjct: 270 PIISGDRVSVTVTGSLVIVNSRS---SDSGEYVCTARNLLGE 308 Score = 43.2 bits (97), Expect = 0.005 Identities = 58/223 (26%), Positives = 93/223 (41%), Gaps = 34/223 (15%) Query: 3698 TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDI 3757 +V I+D++ G + C G P + W +G+ V +++ G L I Sbjct: 128 SVNIRDSVTAFLGSTLRIRCSAN--GLPAPEVKWSKDGQRV-----VKDVDENG--TLSI 178 Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS 3817 DAG Y C A N GS + V+E P+ ++ + + GR Sbjct: 179 VLRRTTDAGRYVCTAVNAIGSDEAETFV-------YVVEPNYPRIVAKKGLATALDGR-- 229 Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877 PI + I++ T S + +C V PK ++W + G+ + SG R Sbjct: 230 -----RPIAG---QIGMTIRTLT---STSITLKCPVTGS--PKPLVDWSKTGQPIISGDR 276 Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920 +V G SL I+ + DSGEY+C A N GED +T++ Sbjct: 277 V-SVTVTG--SLVIVNSRSSDSGEYVCTARNLLGEDSAVSTVN 316 Score = 41.1 bits (92), Expect = 0.021 Identities = 59/231 (25%), Positives = 91/231 (39%), Gaps = 46/231 (19%) Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR--PFATGS 3742 I ED KP + I + V EG V C V+ G P I W + GR P + G+ Sbjct: 14 IRTEDRKP----VSTTIGSRVTVLEGTSVSIKCPVQ--GIPAPAITWSNGGRFLPVSNGN 67 Query: 3743 RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQG 3802 + L++ D GEY C A + G+ + +T VL Q P Sbjct: 68 SILVLSN----------TRVSDTGEYMCTAMSPIGADAASTLLT-------VLAPQKPS- 109 Query: 3803 MSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862 +SG + GR+ P+ T + S T +R C P+ Sbjct: 110 ISGPVV-----GRVI------PLTKTKAVSVNIRDSVTAFLGSTLRIRCSANGLPAPE-- 156 Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913 ++W ++G+ + + V + G +L I+ D+G Y+C AVN G D Sbjct: 157 VKWSKDGQRV-----VKDVDENG--TLSIVLRRTTDAGRYVCTAVNAIGSD 200 Score = 40.7 bits (91), Expect = 0.028 Identities = 41/185 (22%), Positives = 67/185 (36%), Gaps = 16/185 (8%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V EG ++ C + G P P + W G + + S L +S D G+Y Sbjct: 32 VLEGTSVSIKCPVQGIPAPAITWSNGGRFLPVSN--------GNSILVLSNTRVSDTGEY 83 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQAD-NLPALTPLRDIVVYEGQPAQFKTQITSKIKPT- 4751 C A + G + L V P + + P + + + + + +T+ + T Sbjct: 84 MCTAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTKAVSVNIRDSVTAFLGSTL 143 Query: 4752 -IQWLREGALIPE---TPDFQMIHE--GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805 I+ G PE + D Q + + N L I D G + C A A G E Sbjct: 144 RIRCSANGLPAPEVKWSKDGQRVVKDVDENGTLSIVLRRTTDAGRYVCTAVNAIGSDEAE 203 Query: 4806 AKLVV 4810 + V Sbjct: 204 TFVYV 208 Score = 40.7 bits (91), Expect = 0.028 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 9/100 (9%) Query: 252 ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADA------QFQVQLSGNPRPRVTWFKNGQR 305 +S EI RS P + P P + + + A + Q +G P P V W K+GQ Sbjct: 764 VSPEIVRSDEPRTIPPGDGSPLTATVGDNITALTNTQVTLRCQATGTPMPSVIWSKDGQV 823 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345 L++ +H I + + ++ ++ D G YT A N +G Sbjct: 824 LVSGPRHVI---NKNGSIVIQKASPVDRGRYTCTARNSHG 860 Score = 40.3 bits (90), Expect = 0.037 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 5/86 (5%) Query: 3988 METTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYL 4047 + +T + G P V+W G+P++ +R + V +N DSGEY+ Sbjct: 243 LTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTVTGSLVIVNSR---SSDSGEYV 299 Query: 4048 CRATNLYGMDETKAVIKTTG--KPGI 4071 C A NL G D + + +PGI Sbjct: 300 CTARNLLGEDSAVSTVNILNPVRPGI 325 Score = 40.3 bits (90), Expect = 0.037 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 3/63 (4%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G PK V+W + G PI + +R++ V +N + DSG Y C A N LGE Sbjct: 256 GSPKPLVDWSKTGQPIISGDRVSVTVTGSLVIVNSR---SSDSGEYVCTARNLLGEDSAV 312 Query: 1798 STL 1800 ST+ Sbjct: 313 STV 315 Score = 39.1 bits (87), Expect = 0.086 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 6/128 (4%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG--SAT 3780 G P +DW G+P +G RV ++ G +L I + D+GEY C A N G SA Sbjct: 256 GSPKPLVDWSKTGQPIISGDRV-SVTVTG--SLVIVNSRSSDSGEYVCTARNLLGEDSAV 312 Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE-EPIVSTPPKFITQIKSH 3839 +T I + I + G + G+ P + ++S P K + + K Sbjct: 313 STVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKGVPRPKII 372 Query: 3840 TVEESEGV 3847 + E+E V Sbjct: 373 WLRENEVV 380 Score = 38.7 bits (86), Expect = 0.11 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 6/59 (10%) Query: 97 GNPTPVVSWTRKKAPL-VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154 G P P ++W+R + + Y + T + SL+++++ D G YTCTARN +G+ Sbjct: 698 GVPAPTITWSRNGQEMPANGDGYLV-----TNNGSLILEKVSSSDIGRYTCTARNAFGK 751 Score = 38.3 bits (85), Expect = 0.15 Identities = 66/278 (23%), Positives = 103/278 (37%), Gaps = 47/278 (16%) Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSK--------GQKPRFTTHI 3155 G +L + T+ +D+G Y C A + G S L + K G+ T Sbjct: 66 GNSILVLSNTRVSDTGEYMCTAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTK 125 Query: 3156 QNIEGLKD------GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVL 3209 ++D G + C+ + P++K W +GQ + +K V + G L Sbjct: 126 AVSVNIRDSVTAFLGSTLRIRCSANGLPAPEVK--WSKDGQRV-----VKDVDENG--TL 176 Query: 3210 DIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269 I + D+G YVC A N G D + +E P +AK +L G Sbjct: 177 SIVLRRTTDAGRYVCTAVNAIGSDEAETFV-------YVVEPNYPRIVAKKGLATALDGR 229 Query: 3270 QQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329 + P A QI + + S + + P V+W G+ + G Sbjct: 230 R------PIA------GQIGMTIRTLTSTSITLKCPV--TGSPKPLVDWSKTGQPIISGD 275 Query: 3330 RYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDS 3367 R +VI++ +SGEY C A N LG DS Sbjct: 276 RVSVTVTGSLVIVN---SRSSDSGEYVCTARNLLGEDS 310 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 4/60 (6%) Query: 1470 PVTDSNLK-VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528 PVT S V+W K GQP+ G R + G +L I++ + DSG Y C A NL+G D Sbjct: 253 PVTGSPKPLVDWSKTGQPIISGDRVS-VTVTG--SLVIVNSRSSDSGEYVCTARNLLGED 309 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 8/81 (9%) Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557 S + V EG V + G P P ITW G +P G S L + + SD Sbjct: 28 SRVTVLEGTSVSIKCPVQGIPAPAITWSNGG-RFLP-------VSNGNSILVLSNTRVSD 79 Query: 558 AAWYQCTAQNVAGSTATRARL 578 Y CTA + G+ A L Sbjct: 80 TGEYMCTAMSPIGADAASTLL 100 Score = 37.1 bits (82), Expect = 0.35 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 2/48 (4%) Query: 4132 CRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGK 4179 C VTG PKP V W G I++G R +T G I +R D+G+ Sbjct: 252 CPVTGSPKPLVDWSKTGQPIISGDRVSVTVTG--SLVIVNSRSSDSGE 297 Score = 36.7 bits (81), Expect = 0.46 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ--ATTSANLT 1000 V+W K G+P+ + R++ V + +S D+G Y C A N +G+ A ++ N+ Sbjct: 262 VDWSKTGQPIISGDRVSVTVTGSLVIVNSRS---SDSGEYVCTARNLLGEDSAVSTVNIL 318 Query: 1001 IVTKKDIIAESQHPGGL 1017 + I A H L Sbjct: 319 NPVRPGIFASYGHINAL 335 Score = 36.3 bits (80), Expect = 0.61 Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 8/122 (6%) Query: 1865 ECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINN 1924 +C + P P V+W G+ + SG R + +L I+ DSGEY C A N Sbjct: 251 KCPVTGSPKP--LVDWSKTGQPIISGDRVSVTVT---GSLVIVNSRSSDSGEYVCTARNL 305 Query: 1925 LGQ--AVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAV-QDDSFVVEKPQFG 1981 LG+ AVS++ + + I H +AL + + +V D S V+ P G Sbjct: 306 LGEDSAVSTVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKG 365 Query: 1982 KP 1983 P Sbjct: 366 VP 367 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 6/106 (5%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 P IV +VT +E I G P ++ W +NG +I R+ + G ++ Sbjct: 451 PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRY-RVTADG-VT 506 Query: 696 LDMLSLNIQDSGEYTCRAVSATG--VAETKAVLHVTPRATIERTSQ 739 + + + D+G +TC A + G A + ++ + + +IERT++ Sbjct: 507 MLIDGAVVSDTGSFTCEAENFAGKDKATSAVIVKIPAKPSIERTNK 552 Score = 36.3 bits (80), Expect = 0.61 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840 +N+ E I CN P ++ W N + G RY+ T D V++ I Sbjct: 459 DNVTVLEDSTIRIVCNATGL--PAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGAVV 514 Query: 2841 EDSGIYTCKATNSKG 2855 D+G +TC+A N G Sbjct: 515 SDTGSFTCEAENFAG 529 Score = 35.9 bits (79), Expect = 0.80 Identities = 55/210 (26%), Positives = 84/210 (40%), Gaps = 38/210 (18%) Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379 + +EGT+V ++C +Q G + W G RF P + + L L + D Sbjct: 30 VTVLEGTSVSIKCPVQ--GIPAPAITW-------SNGGRFLPVSNGNSI-LVLSNTRVSD 79 Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDES 1439 +G Y C A + +G S L V+A Q PS + + KT + S Sbjct: 80 TGEYMCTAMSPIGADAASTLLTVLAP-------QKPSISGPV--VGRVIPLTKTKAV--S 128 Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499 V I+ VT G + C + +K W K+GQ V + + + Sbjct: 129 VNIRDS-VT-------AFLGSTLRIRCSANGLPAPEVK--WSKDGQRVV-----KDVDEN 173 Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529 G L I+ D+G Y C AVN +G+DE Sbjct: 174 G--TLSIVLRRTTDAGRYVCTAVNAIGSDE 201 Score = 35.5 bits (78), Expect = 1.1 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G P I W +NGQ + A+ + G + L+ +S + D G YTC A +A G Sbjct: 698 GVPAPTITWSRNGQEMPANGDGYLVTNNGSLILEKVSSS--DIGRYTCTARNAFGKDNAN 755 Query: 724 AVLHVTPRATIERT-SQHPETL 744 + ++V + E S P T+ Sbjct: 756 STVNVMDPVSPEIVRSDEPRTI 777 Score = 35.1 bits (77), Expect = 1.4 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 G P V+W + + I R++ T S+ I + R D G Y+C A NLLGE Sbjct: 256 GSPKPLVDWSKTGQPIISGDRVSVTVTG---SLVIVNSRSSDSGEYVCTARNLLGE 308 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253 +I L+C + G P V+W G+ + G R V I+++ S+D+GEY Sbjct: 247 SITLKCPVT--GSPKPLVDWSKTGQPIISGDRVSVTVTGSLV---IVNSRSSDSGEYVCT 301 Query: 1254 AVNHLGSAHTSAIVRVI 1270 A N LG + V ++ Sbjct: 302 ARNLLGEDSAVSTVNIL 318 Score = 33.5 bits (73), Expect = 4.3 Identities = 16/60 (26%), Positives = 32/60 (53%), Gaps = 2/60 (3%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 + W ++G+ + A+ N G +L ++ V+ D G YTC A NA G+ ++ + ++ Sbjct: 704 ITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGKDNANSTVNVM 761 Score = 33.1 bits (72), Expect = 5.7 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 11/96 (11%) Query: 3138 LECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR 3197 ++ + +++ +KP TT + L +G S +C V + P I W + G R Sbjct: 10 MDVIIRTEDRKPVSTTIGSRVTVL-EGTSVSIKCPVQGIPAP--AITWSNGG-------R 59 Query: 3198 IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233 VS+ G +L ++ T+ D+GEY+C A + G D Sbjct: 60 FLPVSN-GNSILVLSNTRVSDTGEYMCTAMSPIGAD 94 Score = 33.1 bits (72), Expect = 5.7 Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 10/107 (9%) Query: 2358 SAEPFKRPEIPEPVTRQRPVFTQPLQNI---DNIQ--EGQTAHFDCRLIPVGDPTLKVEW 2412 S EP ++P+I P P+ P I DN+ E T C G P +V W Sbjct: 429 SLEP-RKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTW 485 Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 +N I R T D V+M I D G + C A N G+ Sbjct: 486 RQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGK 530 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 3/74 (4%) Query: 942 RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ-ATTSANLT 1000 RV W ++G + R + V + I V D G +TC A N G+ TSA + Sbjct: 482 RVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGKDKATSAVIV 539 Query: 1001 IVTKKDIIAESQHP 1014 + K I + P Sbjct: 540 KIPAKPSIERTNKP 553 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 7/69 (10%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIP 4170 PV ++ VTV EG C V G P P + W NG R+ +G + Sbjct: 21 PVSTTIGSRVTVLEGTSVSIKCPVQGIPAPAITW-------SNGGRFLPVSNGNSILVLS 73 Query: 4171 KTRQYDTGK 4179 TR DTG+ Sbjct: 74 NTRVSDTGE 82 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 10/83 (12%) Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705 VT +EG + + ++ G P I W G+ + S+ G L + + + D Sbjct: 30 VTVLEGTSVSIKCPVQ--GIPAPAITWSNGGRFLPVSN--------GNSILVLSNTRVSD 79 Query: 706 SGEYTCRAVSATGVAETKAVLHV 728 +GEY C A+S G +L V Sbjct: 80 TGEYMCTAMSPIGADAASTLLTV 102 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 10/82 (12%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248 V EG ++ ++C ++ G P + W + GR + V + G L + + +DTG Sbjct: 32 VLEGTSVSIKCPVQ--GIPAPAITWSNGGRFLPVSN--------GNSILVLSNTRVSDTG 81 Query: 1249 EYTVRAVNHLGSAHTSAIVRVI 1270 EY A++ +G+ S ++ V+ Sbjct: 82 EYMCTAMSPIGADAASTLLTVL 103 >SB_59380| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1226 Score = 99.1 bits (236), Expect = 8e-20 Identities = 106/411 (25%), Positives = 160/411 (38%), Gaps = 42/411 (10%) Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 +PP F ++ + P+ W ++ IK PD + H T L Sbjct: 85 QPPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGARIK--PDDR-HVVLTSGAL 141 Query: 4469 IIRQV------FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522 I+ V F D V+ +A NR GT V ++ ++ F Q+ Sbjct: 142 RIQSVQGRRKGFGNDEGVYQCLASNRAGT--------VASRKVTLHIAVLSRKFEEQPQS 193 Query: 4523 VNVTSGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581 +N G R KV P + W NG+ + P R+ +L L I D Sbjct: 194 INAWEGTTARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGA---LQIHNVQQVDQ 250 Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641 G Y+CVA N A R + T Q K++ P P +++ +A+ Sbjct: 251 GTYQCVASNIARIRRSN---------TATLTVQQAKSSKQPNFTTIPSNTSVISGEEAV- 300 Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701 C G P+PTVQW K + Y +++ LRI A P+D G+Y C+ S Sbjct: 301 LECIATGVPVPTVQWKKVGGADRAYDY-SLAKPGG-CNLRIRSASPKDGGEYMCIVSASG 358 Query: 4702 GRVTVAAKLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760 +T + L V +P N P L L DI G + T P I WL+ G Sbjct: 359 RSMTHSTFLSVQEPPHFINTPKLPKGLLDI----GATLTLQCSATGVPPPRITWLKNG-- 412 Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 E Q G N L+I + +D+G + C A G V+TS +++V+ Sbjct: 413 -KELVGNQR-QSGINNDLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVR 461 Score = 81.8 bits (193), Expect = 1e-14 Identities = 78/315 (24%), Positives = 127/315 (40%), Gaps = 45/315 (14%) Query: 267 KIAQKPRNSKLQEGADAQFQVQLS-GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 K ++P++ EG A+F ++ P P ++W NGQ ++ S +H ++ + L++ Sbjct: 186 KFEEQPQSINAWEGTTARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLP---NGALQI 242 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 N Q+ D G Y +A N + +RS T T Q+ Sbjct: 243 HNVQQVDQGTYQCVASN-------------------IARIRRSNTATLTVQQ-------- 275 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNE 444 ++ + P F + + V G+ +C TG P P V W + DY+ + + Sbjct: 276 AKSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVGGADRAYDYS----LAK 331 Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVR 503 G L I + + D G C+ L+V E + PK + L++ Sbjct: 332 PGGCNLRIRSASPKDGGEYMCIVSASGRSMTHSTFLSVQEPPHFINTPKLPK--GLLDI- 388 Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563 G + L A G P PRITW K+G ++ N G + L I D+ YQC Sbjct: 389 -GATLTLQCSATGVPPPRITWLKNGKELVGNQ----RQSGINNDLVIQSLSTKDSGVYQC 443 Query: 564 TAQNVAGSTATRARL 578 A+N GS T R+ Sbjct: 444 FAENDIGSVQTSTRV 458 Score = 72.9 bits (171), Expect = 6e-12 Identities = 82/333 (24%), Positives = 127/333 (38%), Gaps = 37/333 (11%) Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305 G+S + I ++ S + PP+ ++P + Q P R W K+G R Sbjct: 67 GKSSIDIYFDLGGSSNLLQPPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGAR 126 Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365 + ++H ++T+ LR+++ Q G N G Y + S V Sbjct: 127 IKPDDRHVVLTSG---ALRIQSVQGRRKGF-----GNDEGV-----YQCLASNRAGTVAS 173 Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVT 424 ++ R+ EE+ PQ + + EG RF C+V P P ++ Sbjct: 174 RKVTLHIAVLSRKFEEQ---------PQSI------NAWEGTTARFSCKVKKAYPAPSIS 218 Query: 425 WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVI 483 W N + I H +L N AL I NV D G CVA N + + L V Sbjct: 219 WEHNGQVIVPSKRHVVLPNG----ALQIHNVQQVDQGTYQCVASNIARIRRSNTATLTVQ 274 Query: 484 EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543 + + P F S +V GE VL A G P P + W+K G + + G Sbjct: 275 QAKSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVG-GADRAYDYSLAKPG 333 Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 G + L I A D Y C + +G + T + Sbjct: 334 GCN-LRIRSASPKDGGEYMCIV-SASGRSMTHS 364 Score = 54.0 bits (124), Expect = 3e-06 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 6/100 (6%) Query: 265 PPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 PP P+ K L GA Q +G P PR+TW KNG+ L+ + + I + Sbjct: 372 PPHFINTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGI----NND 427 Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362 L +++ DSG Y AEN G + TS + V +Y Sbjct: 428 LVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVRRSVNTY 467 Score = 53.2 bits (122), Expect = 5e-06 Identities = 52/200 (26%), Positives = 79/200 (39%), Gaps = 18/200 (9%) Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465 K SK P FT V E+A E G P+P ++W + + D+ + Sbjct: 277 KSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVG-GADRAYDYSLAKPGGC 335 Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN- 4524 + L IR +D + + G + S L V+E PP F T + Sbjct: 336 N-LRIRSASPKDGGEYMCIVSASGRSMTHSTFLSVQE----------PPHFINTPKLPKG 384 Query: 4525 -VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583 + G + L TG P + WLKNGK++ + R + D L+I +DSG Sbjct: 385 LLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGINND----LVIQSLSTKDSGV 440 Query: 4584 YECVAINSAGEARCDAECVV 4603 Y+C A N G + +V Sbjct: 441 YQCFAENDIGSVQTSTRVLV 460 Score = 45.2 bits (102), Expect = 0.001 Identities = 46/158 (29%), Positives = 65/158 (41%), Gaps = 10/158 (6%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141 I W +NG+ I S R V G L+I + D GTY C A+N + V Sbjct: 217 ISWEHNGQVIVPSKR-HVVLPNG--ALQIHNVQQVDQGTYQCVASNIARIRRSNTATLTV 273 Query: 3142 DKSKGQK-PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 ++K K P FTT I + + G+ A EC V P ++W G R + Sbjct: 274 QQAKSSKQPNFTT-IPSNTSVISGEEAVLECIATGVPVP--TVQWKKVGGADR--AYDYS 328 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRAT 3238 ++ G L I D GEY+C + G T +T Sbjct: 329 LAKPGGCNLRIRSASPKDGGEYMC-IVSASGRSMTHST 365 Score = 43.6 bits (98), Expect = 0.004 Identities = 50/187 (26%), Positives = 73/187 (39%), Gaps = 16/187 (8%) Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105 +PP F ++ + + + S I T + W +G I+ R + + + Sbjct: 85 QPPRFVEEPSAVIALRKSTV-QINCSTIATPVARTI--WLKDGARIKPDDRHVVLTSGAL 141 Query: 3106 VVLEILGTKT---TDSGTYSCRATNKWGQ-AEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161 + + G + D G Y C A+N+ G A V L S+ +F Q+I Sbjct: 142 RIQSVQGRRKGFGNDEGVYQCLASNRAGTVASRKVTLHIAVLSR----KFEEQPQSINAW 197 Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221 +G +A F C V P I W HNGQ + S R V G L I Q D G Sbjct: 198 -EGTTARFSCKVKKAY-PAPSISWEHNGQVIVPSKR-HVVLPNG--ALQIHNVQQVDQGT 252 Query: 3222 YVCRAYN 3228 Y C A N Sbjct: 253 YQCVASN 259 Score = 41.9 bits (94), Expect = 0.012 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 7/104 (6%) Query: 1439 SVTIKPRFVTRPKSIENVIE-GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH 1497 SV P F+ PK + +++ G + +C V ++ W KNG+ + R I+ Sbjct: 368 SVQEPPHFINTPKLPKGLLDIGATLTLQCSATGVPPP--RITWLKNGKELVGNQRQSGIN 425 Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541 + L I L +DSG+Y C A N +G+ + S R+ R + + Sbjct: 426 N----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVRRSVN 465 Score = 41.5 bits (93), Expect = 0.016 Identities = 41/144 (28%), Positives = 59/144 (40%), Gaps = 12/144 (8%) Query: 3509 SMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPS--D 3566 S+ G N+ + S PK G I + G S T T E PP F TP Sbjct: 328 SLAKPGGCNLRIRSASPKD-GGEYMCIVSASGRSMTHSTFLSVQE---PPHFINTPKLPK 383 Query: 3567 LILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRD 3626 +L ++ +C V R+ W NGK L+ R IN+ L I + +D Sbjct: 384 GLLDIGATLTLQCSATGVPPP--RITWLKNGKELVGNQRQSGINND----LVIQSLSTKD 437 Query: 3627 AGLYTCKATNRHGEATVSCKLQVK 3650 +G+Y C A N G S ++ V+ Sbjct: 438 SGVYQCFAENDIGSVQTSTRVLVR 461 Score = 41.1 bits (92), Expect = 0.021 Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 7/101 (6%) Query: 1838 VAVNQAPRFITQLNGPTKLSE-GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896 ++V + P FI P L + G + +C P P R+ W NGK L R Sbjct: 367 LSVQEPPHFINTPKLPKGLLDIGATLTLQCSATGVPPP--RITWLKNGKELVGNQRQSGI 424 Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 N+ L I ++ +DSG Y C A N++G +S R+ V+ Sbjct: 425 NN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVR 461 Score = 40.7 bits (91), Expect = 0.028 Identities = 31/83 (37%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDS 2179 N EG A F C+V+ P +I W HNGQ I R+ + AL I D Sbjct: 195 NAWEGTTARFSCKVKKAY-PAPSISWEHNGQVIVPSKRHVVLPNG---ALQIHNVQQVDQ 250 Query: 2180 GTYMCKATNKLG-EAVNTCTLKV 2201 GTY C A+N NT TL V Sbjct: 251 GTYQCVASNIARIRRSNTATLTV 273 Score = 39.9 bits (89), Expect = 0.049 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 4113 FVSLPDAVTVEEGEWARFCCRVT-GHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPK 4171 F P ++ EG ARF C+V +P P + W NG IV R+ + +G I Sbjct: 187 FEEQPQSINAWEGTTARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGA--LQIHN 244 Query: 4172 TRQYDTGKIEVI 4183 +Q D G + + Sbjct: 245 VQQVDQGTYQCV 256 Score = 39.9 bits (89), Expect = 0.049 Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464 G C TG P P +TW N +++ + +SG N+ L+I +++ DSGV Sbjct: 389 GATLTLQCSATGVPPPRITWLKNGKELVGNQR------QSGINNDLVIQSLSTKDSGVYQ 442 Query: 465 CVARNKSGETAFQCRLNV 482 C A N G R+ V Sbjct: 443 CFAENDIGSVQTSTRVLV 460 Score = 39.1 bits (87), Expect = 0.086 Identities = 20/66 (30%), Positives = 38/66 (57%), Gaps = 4/66 (6%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P R+ WL+NG + + R + +++ L ++ ++ +DSG Y C A N++G TS Sbjct: 400 GVPPPRITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTS 455 Query: 1798 STLFVQ 1803 + + V+ Sbjct: 456 TRVLVR 461 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 5/79 (6%) Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437 F + Q+I N EG TA F C+ + P + W N ++I S R + ++ Sbjct: 187 FEEQPQSI-NAWEGTTARFSCK-VKKAYPAPSISWEHNGQVIVPSKRHVVLPNG---ALQ 241 Query: 2438 ISHVRDEDEGVYMCRASNL 2456 I +V+ D+G Y C ASN+ Sbjct: 242 IHNVQQVDQGTYQCVASNI 260 Score = 38.3 bits (85), Expect = 0.15 Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 12/108 (11%) Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360 V+E + P+ + L +I G + L+C G R+ W NGK + G++ + Sbjct: 369 VQEPPHFINTPKLPKGLLDI----GATLTLQC--SATGVPPPRITWLKNGKEL-VGNQRQ 421 Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408 D V + S+ +DSGVY C A N +G TS RV+ ++ + Sbjct: 422 SGINNDLV---IQSLSTKDSGVYQCFAENDIGSVQTS--TRVLVRRSV 464 Score = 37.9 bits (84), Expect = 0.20 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%) Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692 V PP FI K + + G P +I WLKNG+ + + R + I Sbjct: 369 VQEPPHFINTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGINN-- 426 Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAET 722 L + SL+ +DSG Y C A + G +T Sbjct: 427 --DLVIQSLSTKDSGVYQCFAENDIGSVQT 454 Score = 37.5 bits (83), Expect = 0.26 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 4/60 (6%) Query: 942 RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 R+ WLK+G+ + + R + N L I+S++ D+G Y C A N IG TS + + Sbjct: 405 RITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLV 460 Score = 36.7 bits (81), Expect = 0.46 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 9/100 (9%) Query: 770 PQFIR-PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828 P FI P G L G + T V P R+ W K+G+ + + R + I N Sbjct: 373 PHFINTPKLPKGLLDIGATLTLQCSATGVPPP--RITWLKNGKELVGNQRQSGINN---- 426 Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868 L I L +D+G Y A N +G ++ T S RV R +V Sbjct: 427 DLVIQSLSTKDSGVYQCFAENDIG-SVQT-STRVLVRRSV 464 Score = 35.9 bits (79), Expect = 0.80 Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 11/123 (8%) Query: 3525 PKGMEGTIDKI--AALEGYSGTVDTLTPEAESGN---PPEFTTTPSDLILSENSSAHFEC 3579 P+ E T+ ++ A L+G S ++D S N PP F PS +I S+ C Sbjct: 50 PRDPERTLVRLDYAKLQGKS-SIDIYFDLGGSSNLLQPPRFVEEPSAVIALRKSTVQINC 108 Query: 3580 RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV---YQRDAGLYTCKATN 3636 I + R W +G + R + I + G + D G+Y C A+N Sbjct: 109 STIATPVA--RTIWLKDGARIKPDDRHVVLTSGALRIQSVQGRRKGFGNDEGVYQCLASN 166 Query: 3637 RHG 3639 R G Sbjct: 167 RAG 169 Score = 35.9 bits (79), Expect = 0.80 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 11/129 (8%) Query: 3405 VRRKDTS---VEEEKG-KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460 +RR +T+ V++ K K P FT SN + GE A E T P V+W G Sbjct: 263 IRRSNTATLTVQQAKSSKQPNFTTIPSNTSVI-SGEEAVLECIATGVPVPT--VQWKKVG 319 Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS-MKVQGKRNII 3519 + +A + G L I P+D GEY+C + G ++T ++ + VQ + I Sbjct: 320 GADRAYDY--SLAKPGGCNLRIRSASPKDGGEYMC-IVSASGRSMTHSTFLSVQEPPHFI 376 Query: 3520 LESQLPKGM 3528 +LPKG+ Sbjct: 377 NTPKLPKGL 385 Score = 35.9 bits (79), Expect = 0.80 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 G P RI W NG+ R +N+ L I + +D+G Y C A N GS T+ Sbjct: 400 GVPPPRITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTS 455 Query: 3783 AKI 3785 ++ Sbjct: 456 TRV 458 Score = 35.5 bits (78), Expect = 1.1 Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Query: 3559 EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILE 3618 +F P + E ++A F C++ + + W HNG+ ++ R + + L+ Sbjct: 186 KFEEQPQSINAWEGTTARFSCKVKKAYPAPS-ISWEHNGQVIVPSKRHVVLPNGA---LQ 241 Query: 3619 IGGVYQRDAGLYTCKATN 3636 I V Q D G Y C A+N Sbjct: 242 IHNVQQVDQGTYQCVASN 259 Score = 35.5 bits (78), Expect = 1.1 Identities = 28/98 (28%), Positives = 37/98 (37%), Gaps = 4/98 (4%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885 V PP FI K G + P RI W +NGK L R + + Sbjct: 369 VQEPPHFINTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGINN-- 426 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 L I + +DSG Y C A ND G T + ++ Sbjct: 427 --DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVRR 462 Score = 35.5 bits (78), Expect = 1.1 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 4110 PPVFVSLPDAVT--VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156 PP F++ P ++ G C TG P PR+ WL NG +V R Sbjct: 372 PPHFINTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQR 420 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P +I W KNG L G + +S + LV I SL DSG+Y C A N +G ++ Sbjct: 402 PPPRITWLKNGKELV-GNQRQSGINNDLV---IQSLSTKDSGVYQCFAENDIGSVQTSTR 457 Query: 2732 IKI 2734 + + Sbjct: 458 VLV 460 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 4/67 (5%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669 ++ W N K L R + NN L I S +DSG Y C A N +G TS +V Sbjct: 405 RITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLV 460 Query: 1670 HSKKSIY 1676 + Y Sbjct: 461 RRSVNTY 467 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Query: 2253 HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDA 2312 + +EG TA F C+V+ + P I + HNG+ + + R H+ G +L I + D Sbjct: 195 NAWEGTTARFSCKVKKAY-PAPSISWEHNGQVIVPSKR-HVVLPNG--ALQIHNVQQVDQ 250 Query: 2313 GEYSVKAIN 2321 G Y A N Sbjct: 251 GTYQCVASN 259 Score = 34.7 bits (76), Expect = 1.9 Identities = 17/48 (35%), Positives = 24/48 (50%) Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144 T V+++K+ P F ++P +V GE A C TG P P V W Sbjct: 268 TATLTVQQAKSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQW 315 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/86 (29%), Positives = 32/86 (37%), Gaps = 4/86 (4%) Query: 61 ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120 +T + P F I N G A E G P P V W +K YS+ Sbjct: 271 LTVQQAKSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQW-KKVGGADRAYDYSL 329 Query: 121 RYNEQTGDVSLLIKQIGPGDEGEYTC 146 + G +L I+ P D GEY C Sbjct: 330 ---AKPGGCNLRIRSASPKDGGEYMC 352 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 2/93 (2%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P P N+ + G +A + +G P P V W K G + + LR+ Sbjct: 282 PNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVGG--ADRAYDYSLAKPGGCNLRI 339 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 R+ D G Y + + S +L+V+ P Sbjct: 340 RSASPKDGGEYMCIVSASGRSMTHSTFLSVQEP 372 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 5/90 (5%) Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029 ++PP F+ + L+++ T Q + G P ++ W NGK L+ R + I + Sbjct: 370 QEPPHFINTPKLPKGLLDIGAT-LTLQCSATGVPPPRITWLKNGKELVGNQRQSGINN-D 427 Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDET 4059 V + +DSG Y C A N G +T Sbjct: 428 LVIQSLS---TKDSGVYQCFAENDIGSVQT 454 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251 G + L+C G P R+ W NG+ + VG++ ++ + V + ++ D+G Y Sbjct: 389 GATLTLQC--SATGVPPPRITWLKNGKEL-VGNQRQSGINNDLVIQSL---STKDSGVYQ 442 Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVT 1277 A N +GS TS RV+ R + T Sbjct: 443 CFAENDIGSVQTS--TRVLVRRSVNT 466 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 4/70 (5%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 P +I W N K L R ++ L I +DSG+Y C A N GS TS Sbjct: 402 PPPRITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTR 457 Query: 2863 LRCTGDKNIY 2872 + N Y Sbjct: 458 VLVRRSVNTY 467 Score = 32.7 bits (71), Expect = 7.5 Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 11/123 (8%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 TG I W NGK + + R + +V++ L TK DSG Y C A N G + Sbjct: 399 TGVPPPRITWLKNGKELVGNQRQSGIN--NDLVIQSLSTK--DSGVYQCFAENDIGSVQT 454 Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194 S ++ V +S P N+ G+ S + +P P+ + + N QP Sbjct: 455 STRV-LVRRSVNTYPPL-----NVTGV-GISSEEVNISWLPPRGPEQVLAYSINYQPADK 507 Query: 3195 STR 3197 S++ Sbjct: 508 SSK 510 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 6/67 (8%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 + W NGK++ R ++ L I S+ +DSGVY A N G Q S + V Sbjct: 406 ITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLV- 460 Query: 1137 TRSSIDT 1143 R S++T Sbjct: 461 -RRSVNT 466 >SB_57926| Best HMM Match : I-set (HMM E-Value=3.5e-39) Length = 788 Score = 97.1 bits (231), Expect = 3e-19 Identities = 80/296 (27%), Positives = 126/296 (42%), Gaps = 28/296 (9%) Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577 ++ + VT V + GT + W NG++V + R + G YT+L +A Sbjct: 238 VSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESV-SSSGDYTILQTKA- 295 Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637 +DSG +C+A N AG A K P I P +D V G Sbjct: 296 -EDSGVIQCLASNDAGHVMGRA---------------LLKILGIPIWITLPPRDTSVTIG 339 Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697 + + F C+ G P PTV W+KG +I S + L+I+ D G Y C+A Sbjct: 340 ETVVFDCQTRGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYTCLA 399 Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQIT--SKIKPTIQWL 4755 NS G +A+LKV N+ P R I + +G + S I W Sbjct: 400 RNSLGVKNASAELKVL---AQTNITTPLPPRTIAI-KGYSITLAVGVNKDSLISLRFTWT 455 Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 ++G+ + + P Q++ G+ A+ + ++ D GT+ C ++ G TS LVV+ Sbjct: 456 KDGSSVTD-PRMQILANGSLAITAV---HDSDAGTYKCVVSSDVGNASTSTVLVVQ 507 Score = 78.6 bits (185), Expect = 1e-13 Identities = 52/172 (30%), Positives = 79/172 (45%), Gaps = 7/172 (4%) Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 SC+ G P PT+ WY + + + +S + D YT+ ++A ED G +C+A N AG Sbjct: 254 SCRARGTPTPTITWYNNGRRVFANSRESVSSSGD-YTILQTKA--EDSGVIQCLASNDAG 310 Query: 4703 RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 V A LK+ LP RD V G+ F Q PT+ W + ++I Sbjct: 311 HVMGRALLKILGIPIWITLPP----RDTSVTIGETVVFDCQTRGNPTPTVTWWKGSSVID 366 Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 + H+ ++ L I T D G +TC A + G SA+L V ++T Sbjct: 367 ISSPSTRFHQKSDGALQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQT 418 Score = 73.7 bits (173), Expect = 3e-12 Identities = 50/167 (29%), Positives = 78/167 (46%), Gaps = 10/167 (5%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 CR G P P +TW+ N R++ N + V+ SG++ ++ T DSGV+ C+A N +G Sbjct: 255 CRARGTPTPTITWYNNGRRV--FANSRESVSSSGDYTILQTKA--EDSGVIQCLASNDAG 310 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI- 531 + L ++ + R +++ + GE VV + + G PTP +TW K I Sbjct: 311 HVMGRALLKILGIPIWIT--LPPRDTSVTI--GETVVFDCQTRGNPTPTVTWWKGSSVID 366 Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 I +P R H + L I + D Y C A+N G A L Sbjct: 367 ISSPSTRFHQKSDGA-LQITGTQRVDNGVYTCLARNSLGVKNASAEL 412 Score = 72.9 bits (171), Expect = 6e-12 Identities = 51/176 (28%), Positives = 79/176 (44%), Gaps = 7/176 (3%) Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458 +D VT G+ FDC+ G P P VTW+ I D + ++ + AL IT Sbjct: 332 RDTSVTIGETVVFDCQTRGNPTPTVTWWKGSSVI-DISSPSTRFHQKSDGALQITGTQRV 390 Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518 D+GV TC+ARN G L V+ + + P + V +N ++ Sbjct: 391 DNGVYTCLARNSLGVKNASAELKVLAQTNITTPLPPRTIAIKGYSITLAVGVNKDSL--I 448 Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574 + R TW KDG + +P ++I +G +L I SDA Y+C + G+ +T Sbjct: 449 SLRFTWTKDG-SSVTDPRMQILANG---SLAITAVHDSDAGTYKCVVSSDVGNAST 500 Score = 51.2 bits (117), Expect = 2e-05 Identities = 71/287 (24%), Positives = 106/287 (36%), Gaps = 39/287 (13%) Query: 4436 GEPLPLIKWYRENFPI-KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494 G P P I WY + NS + + S+ I Q EDS V +A N G Sbjct: 259 GTPTPTITWYNNGRRVFANSRE----SVSSSGDYTILQTKAEDSGVIQCLASNDAGHVMG 314 Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554 A L + +P TL ++ +VT G+ V D + G V W K + Sbjct: 315 RALLKILG---------IPIWITLPPRDTSVTIGETVVFDCQTRGNPTPTVTWWKGSSVI 365 Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614 + + L I D+G Y C+A NS G AE V Sbjct: 366 DISSPSTRFHQKSDGALQITGTQRVDNGVYTCLARNSLGVKNASAELKVL---------- 415 Query: 4615 QTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQ--WYK-GDKLIKPSKYFQ 4670 A I PL + +A +G +I + + L +++ W K G + P + Sbjct: 416 ------AQTNITTPLPPRTIAIKGYSITLAVGVNKDSLISLRFTWTKDGSSVTDP----R 465 Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717 M A+ +L I+ D G YKCV + G + + L V +Q Sbjct: 466 MQILANG-SLAITAVHDSDAGTYKCVVSSDVGNASTSTVLVVQDANQ 511 Score = 51.2 bits (117), Expect = 2e-05 Identities = 31/95 (32%), Positives = 43/95 (45%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 P I PR++ + G F Q GNP P VTW+K + S+ + L+ Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTRGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQ 383 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359 + TQ+ D+G YT LA N G S L V + T Sbjct: 384 ITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQT 418 Score = 49.2 bits (112), Expect = 8e-05 Identities = 47/179 (26%), Positives = 77/179 (43%), Gaps = 13/179 (7%) Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484 E F+ + G P P + W++ + I +SP + H S ++ I V D+ V+ + Sbjct: 340 ETVVFDCQTRGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRV-DNGVYTCL 398 Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544 A N G SA L V + +PP T+ + ++T V D+ ++ + Sbjct: 399 ARNSLGVKNASAELKVLAQTNITTP--LPPR-TIAIKGYSITLAVGVNKDSLIS----LR 451 Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603 W K+G V D R +IL +L I + D+G Y+CV + G A VV Sbjct: 452 FTWTKDGSSVT-DPRMQILANG---SLAITAVHDSDAGTYKCVVSSDVGNASTSTVLVV 506 Score = 48.0 bits (109), Expect = 2e-04 Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 7/85 (8%) Query: 2123 EGDRAHFECRV----EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAED 2178 +G FEC V P TI W++NG+++ A R + Y IL T AED Sbjct: 241 KGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYT---ILQTKAED 297 Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAG 2203 SG C A+N G + LK+ G Sbjct: 298 SGVIQCLASNDAGHVMGRALLKILG 322 Score = 47.2 bits (107), Expect = 3e-04 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 2/68 (2%) Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450 G+T FDC+ G+PT V W++ +I+ SS T+ H ++ I+ + D GVY Sbjct: 339 GETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396 Query: 2451 CRASNLLG 2458 C A N LG Sbjct: 397 CLARNSLG 404 Score = 46.8 bits (106), Expect = 4e-04 Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 2/68 (2%) Query: 86 GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145 G F+ + RGNPTP V+W K + +++ + S R++ Q D +L I D G YT Sbjct: 339 GETVVFDCQTRGNPTPTVTWW-KGSSVIDISSPSTRFH-QKSDGALQITGTQRVDNGVYT 396 Query: 146 CTARNQYG 153 C ARN G Sbjct: 397 CLARNSLG 404 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 3/68 (4%) Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 + RA GTPTP ITW +G + N + + G + L + KA D+ QC A N AG Sbjct: 254 SCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYTIL---QTKAEDSGVIQCLASNDAG 310 Query: 571 STATRARL 578 RA L Sbjct: 311 HVMGRALL 318 Score = 46.4 bits (105), Expect = 6e-04 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 2/84 (2%) Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847 G+ + F+C + PT + W+ + + + H S +L IT T D+G+YT Sbjct: 339 GETVVFDCQTRGNPTPT--VTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396 Query: 2848 CKATNSKGSATTSGSLRCTGDKNI 2871 C A NS G S L+ NI Sbjct: 397 CLARNSLGVKNASAELKVLAQTNI 420 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 2/101 (1%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P+++ V+ G+ + +C+ G+PT V W+ + + S ++ A Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT 1277 L I D G YT A N LG + SA ++V+ +++I T Sbjct: 382 LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNITT 422 Score = 42.7 bits (96), Expect = 0.007 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 2/99 (2%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P ++T P +V G+ V F+C+ + V W+K + I H A Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTRG--NPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI 1542 L I D+G+YTC A N +G S L + T+I Sbjct: 382 LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420 Score = 42.7 bits (96), Expect = 0.007 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%) Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117 G++ F+ + + + T TV W+ I ++ +H AL I + D+GVYT Sbjct: 339 GETVVFDCQT--RGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396 Query: 1118 VVARNAAGEAQLSASMTVETRSSIDT 1143 +ARN+ G SA + V +++I T Sbjct: 397 CLARNSLGVKNASAELKVLAQTNITT 422 Score = 41.9 bits (94), Expect = 0.012 Identities = 44/159 (27%), Positives = 64/159 (40%), Gaps = 16/159 (10%) Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135 G + I W+ NG+ + A+ R +V + G IL TK DSG C A+N G Sbjct: 259 GTPTPTITWYNNGRRVFANSR-ESVSSSGDYT--ILQTKAEDSGVIQCLASNDAGHVMGR 315 Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM--- 3192 L+ + P + T + G++ F+C +P + W+ + Sbjct: 316 ALLKILG-----IPIWITLPPRDTSVTIGETVVFDCQT--RGNPTPTVTWWKGSSVIDIS 368 Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 STR SD L I TQ D+G Y C A N G Sbjct: 369 SPSTRFHQKSD---GALQITGTQRVDNGVYTCLARNSLG 404 Score = 41.9 bits (94), Expect = 0.012 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 G P P +TW+ NG+R+ +++ + ++ ++T L+ T+ DSG LA N G ++ Sbjct: 259 GTPTPTITWYNNGRRVFANSRESVSSSGDYTILQ---TKAEDSGVIQCLASNDAGHVMGR 315 Query: 351 GYLAV 355 L + Sbjct: 316 ALLKI 320 Score = 41.9 bits (94), Expect = 0.012 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%) Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMK 1773 T+P +D V + F+ + G+P V W + I+ S+ T H AL + Sbjct: 328 TLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQIT 385 Query: 1774 YVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 D+G YTC A N LG S+ L V ++ ++ Sbjct: 386 GTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420 Score = 40.7 bits (91), Expect = 0.028 Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 2/99 (2%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P+++T ++ G+ F+C+ +P T+ W+ I H A Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207 L I T D+G Y C A N LG + LKV NI Sbjct: 382 LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420 Score = 40.7 bits (91), Expect = 0.028 Identities = 24/71 (33%), Positives = 33/71 (46%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G+ T V W K ++ SS T F AL I D G YTC A N++G S Sbjct: 350 GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYTCLARNSLGVKNAS 409 Query: 997 ANLTIVTKKDI 1007 A L ++ + +I Sbjct: 410 AELKVLAQTNI 420 Score = 39.9 bits (89), Expect = 0.049 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 3/109 (2%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 P +P + + G + F+ + G+PT + W K I+ SS T + + Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744 L + D+G YTC A ++ GV A L V + I T P T+ Sbjct: 382 LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI-TTPLPPRTI 429 Score = 39.9 bits (89), Expect = 0.049 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P +IT T ++ G++ ++C+ P P V W+ V+ + A Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTRGNPTPT--VTWWKGSSVIDISSPSTRFHQKSDGA 381 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942 L I D+G YTC A N+LG +S L V ++ +I Sbjct: 382 LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420 Score = 39.9 bits (89), Expect = 0.049 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 2/88 (2%) Query: 785 GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844 G F+ Q +PT V W+K I SS T +L I + D G YT Sbjct: 339 GETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396 Query: 845 VRAVNKLGEAISTASIRVAARSTVTADL 872 A N LG ++A ++V A++ +T L Sbjct: 397 CLARNSLGVKNASAELKVLAQTNITTPL 424 Score = 38.3 bits (85), Expect = 0.15 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 2/84 (2%) Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384 G V +C+ + G+ T V W+ I ++ AL + D+GVYT Sbjct: 339 GETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396 Query: 1385 CQATNQLGEAVTSCALRVIAKKDL 1408 C A N LG S L+V+A+ ++ Sbjct: 397 CLARNSLGVKNASAELKVLAQTNI 420 Score = 37.9 bits (84), Expect = 0.20 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 7/101 (6%) Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPT----DDPNLKVEWYWNGKSLKAGSRFRTFC 3473 ++ + P I +G+ FE +T + P + WY NG+ + A SR Sbjct: 225 RSSILLGPSHQIAVSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSS 284 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514 + IL+ T EDSG C A N+ G + A +K+ G Sbjct: 285 SGDYTILQ---TKAEDSGVIQCLASNDAGHVMGRALLKILG 322 Score = 37.5 bits (83), Expect = 0.26 Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 5/115 (4%) Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348 Q+L + VR I + + Q + + E V CR + G T + W+ Sbjct: 212 QILSVQSSSYSSVRSSILLGPSHQIAVSGKGQEVTFECFVTGSCRAR--GTPTPTITWYN 269 Query: 1349 NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 NG+ + R + DY +L EDSGV C A+N G + L+++ Sbjct: 270 NGRRVFANSRESVSSSGDYT---ILQTKAEDSGVIQCLASNDAGHVMGRALLKIL 321 Score = 37.5 bits (83), Expect = 0.26 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 3/63 (4%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066 PT + WY NGR V R + Y IL AED+G C A+N G + + Sbjct: 261 PTPTITWYNNGRRVFANSRESVSSSGDYT---ILQTKAEDSGVIQCLASNDAGHVMGRAL 317 Query: 2067 VKV 2069 +K+ Sbjct: 318 LKI 320 Score = 36.7 bits (81), Expect = 0.46 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 7/94 (7%) Query: 1046 LGPLKGTNKIVEGQSAHFEARV----EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101 LGP +GQ FE V + T T+ WY NG+++ + +R Y Sbjct: 230 LGPSHQIAVSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYT 289 Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 L +AEDSGV +A N AG A + + Sbjct: 290 ILQ---TKAEDSGVIQCLASNDAGHVMGRALLKI 320 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 7/88 (7%) Query: 2784 VCKEGDNIHFECNVEPS----RDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839 V +G + FEC V S PT I W+ N + + + +R + Y I T Sbjct: 238 VSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYT---ILQTK 294 Query: 2840 EEDSGIYTCKATNSKGSATTSGSLRCTG 2867 EDSG+ C A+N G L+ G Sbjct: 295 AEDSGVIQCLASNDAGHVMGRALLKILG 322 Score = 36.7 bits (81), Expect = 0.46 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 2/69 (2%) Query: 4132 CRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXX 4191 CR G P P + W NG + SR ++ G Y I +T+ D+G I+ + Sbjct: 255 CRARGTPTPTITWYNNGRRVFANSRESVSSSGDY--TILQTKAEDSGVIQCLASNDAGHV 312 Query: 4192 XXXXXLKVI 4200 LK++ Sbjct: 313 MGRALLKIL 321 Score = 36.7 bits (81), Expect = 0.46 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 3/63 (4%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 PT + WY +GR + A+SR S+ + G I+ +AED+G A N G + A Sbjct: 261 PTPTITWYNNGRRVFANSR-ESVSSSG--DYTILQTKAEDSGVIQCLASNDAGHVMGRAL 317 Query: 860 IRV 862 +++ Sbjct: 318 LKI 320 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 7/87 (8%) Query: 3843 ESEGVRFECRV----EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAED 3898 + + V FEC V + P I WY NG+ + + R +V G IL AED Sbjct: 241 KGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSR-ESVSSSG--DYTILQTKAED 297 Query: 3899 SGEYICRAVNDFGEDFTKATISCKKLP 3925 SG C A ND G +A + +P Sbjct: 298 SGVIQCLASNDAGHVMGRALLKILGIP 324 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 7/84 (8%) Query: 3164 GQSAHFECTVVPV----DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219 GQ FEC V P I WY+NG+ + ++R S + +L T+ DS Sbjct: 242 GQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYTILQ---TKAEDS 298 Query: 3220 GEYVCRAYNKYGEDFTRATINCYG 3243 G C A N G RA + G Sbjct: 299 GVIQCLASNDAGHVMGRALLKILG 322 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 2/99 (2%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P ++T TS+ ET F+CQ G+P V W+ + + T + A Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071 + D+G Y C A N G+ A +K + I Sbjct: 382 LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 2/93 (2%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 PI+ T + G+ V + Q R +P + W+K + + Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQT--RGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L I + D+G+YTC A N LG ++A +K+ Sbjct: 382 LQITGTQRVDNGVYTCLARNSLGVKNASAELKV 414 Score = 35.5 bits (78), Expect = 1.1 Identities = 18/74 (24%), Positives = 33/74 (44%) Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135 G+ + + W+ I+ S + L+I GT+ D+G Y+C A N G S Sbjct: 350 GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYTCLARNSLGVKNAS 409 Query: 3136 VKLECVDKSKGQKP 3149 +L+ + ++ P Sbjct: 410 AELKVLAQTNITTP 423 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 7/73 (9%) Query: 2390 EGQTAHFDCRLIPV----GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDED 2445 +GQ F+C + G PT + W+ N + + +SR + + Y TI + ED Sbjct: 241 KGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDY---TILQTKAED 297 Query: 2446 EGVYMCRASNLLG 2458 GV C ASN G Sbjct: 298 SGVIQCLASNDAG 310 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 2/84 (2%) Query: 3710 GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYT 3769 G V FDC+ G+PT + W+ S + AL I D G YT Sbjct: 339 GETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396 Query: 3770 CRATNKWGSATTTAKITCSAKRDI 3793 C A N G +A++ A+ +I Sbjct: 397 CLARNSLGVKNASAELKVLAQTNI 420 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/101 (24%), Positives = 41/101 (40%), Gaps = 2/101 (1%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G P T P D ++ + F+C+ + + V W+ + S + Sbjct: 322 GIPIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSD 379 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI 3655 L+I G + D G+YTC A N G S +L+V + I Sbjct: 380 GALQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 8/95 (8%) Query: 4111 PVFVSLPDAVT-VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN----GSRYKLTYDGMY 4165 P++++LP T V GE F C+ G+P P V W G+++++ +R+ DG Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTRGNPTPTVTW-WKGSSVIDISSPSTRFHQKSDGA- 381 Query: 4166 HFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVI 4200 I T++ D G + LKV+ Sbjct: 382 -LQITGTQRVDNGVYTCLARNSLGVKNASAELKVL 415 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 4/85 (4%) Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKS-LKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493 GE F+ + P V W W G S + S F L+I+ T D+G Y Sbjct: 339 GETVVFDCQTRGNPTPT--VTW-WKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVY 395 Query: 3494 LCRAYNNYGEAVTTASMKVQGKRNI 3518 C A N+ G +A +KV + NI Sbjct: 396 TCLARNSLGVKNASAELKVLAQTNI 420 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 4/62 (6%) Query: 940 TLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999 +LR W KDG V R+ N G +A+T +V DAG Y C + +G A+TS L Sbjct: 449 SLRFTWTKDGSSV-TDPRMQILAN-GSLAIT--AVHDSDAGTYKCVVSSDVGNASTSTVL 504 Query: 1000 TI 1001 + Sbjct: 505 VV 506 Score = 33.5 bits (73), Expect = 4.3 Identities = 44/187 (23%), Positives = 70/187 (37%), Gaps = 15/187 (8%) Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA--DEYTLRISEA-FPED 4689 ++ EG A+ F C G W D SR ++ L IS +D Sbjct: 34 VIPEGNAVTFYCTASGDLPIQYSWTSADLQNNIRDLTMDSRYTQHNDGRLTISNVQHAKD 93 Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT---PLRDIVVYEGQPAQFKTQITS 4746 +G Y CVA N+ G T ++ + + +PA + P +Y T Sbjct: 94 DGYYHCVAKNNEG--TALSRRAIFRVAYL-TIPASSSSPPTASCYMYSHYKYTLGITDTF 150 Query: 4747 KIKPTIQ--WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT-TAAGQVE 4803 + P Q W + GAL+ ET + +GN L + +D G + T T G Sbjct: 151 PLFPKTQYTWRKSGALLRETDEVSFSSQGN---LYLSRLGFDDIGEYGSEVTNTVTGTSY 207 Query: 4804 TSAKLVV 4810 + K ++ Sbjct: 208 SRPKQIL 214 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 5/71 (7%) Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925 CR P P + WY NG+ + + R S+ + IL EDSG C A N+ Sbjct: 255 CRARGTPTPT--ITWYNNGRRVFANSRESVSSSGDYT---ILQTKAEDSGVIQCLASNDA 309 Query: 1926 GQAVSSIRLNV 1936 G + L + Sbjct: 310 GHVMGRALLKI 320 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 10/99 (10%) Query: 2902 SVPDTEYPKPEWIIPIAAEHQLV---EGQVLHLE----GQVEPKNDPDLKIEWYFNGKVL 2954 SV + Y I + HQ+ +GQ + E G + P I WY NG+ + Sbjct: 215 SVQSSSYSSVRSSILLGPSHQIAVSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRV 274 Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 SR ++S + ++ DSG+ C A N G Sbjct: 275 FANSRESVSSSGDYT---ILQTKAEDSGVIQCLASNDAG 310 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 7/83 (8%) Query: 2656 EGQHVYLEAQV----EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDD 2711 +GQ V E V R P I W+ NG + +R +S G T I + +D Sbjct: 241 KGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSR-ESVSSSGDYT--ILQTKAED 297 Query: 2712 SGIYTCKATNLLGEAVSTASIKI 2734 SG+ C A+N G + A +KI Sbjct: 298 SGVIQCLASNDAGHVMGRALLKI 320 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 3/65 (4%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G PT I W NG+ + A+SR S+ G +L +DSG C A + G + Sbjct: 259 GTPTPTITWYNNGRRVFANSR-ESVSSSG--DYTILQTKAEDSGVIQCLASNDAGHVMGR 315 Query: 724 AVLHV 728 A+L + Sbjct: 316 ALLKI 320 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 4/62 (6%) Query: 1742 LRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801 LR W ++G + R+ + + G +A+ V+ D+GTY C +++G A TS+ L Sbjct: 450 LRFTWTKDGSSV-TDPRMQILAN-GSLAITA--VHDSDAGTYKCVVSSDVGNASTSTVLV 505 Query: 1802 VQ 1803 VQ Sbjct: 506 VQ 507 Score = 32.3 bits (70), Expect = 9.9 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 10/109 (9%) Query: 3698 TVEIKDNIDV-PEGGPVHFDCRVEPVGDPTMRIDWF-----HNGRPFATGSRVHTLNDFG 3751 T +D++ V PEG V F C GD ++ W +N R SR ND Sbjct: 25 TSRARDSVGVIPEGNAVTFYCTAS--GDLPIQYSWTSADLQNNIRDLTMDSRYTQHNDGR 82 Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800 ++ + A+D G Y C A N G+A + I A I S P Sbjct: 83 LTISNVQH--AKDDGYYHCVAKNNEGTALSRRAIFRVAYLTIPASSSSP 129 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 3/63 (4%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P + W NG + A++R + Y L K EDSG C A N+ G + Sbjct: 259 GTPTPTITWYNNGRRVFANSRESVSSSGDYTILQTK---AEDSGVIQCLASNDAGHVMGR 315 Query: 1798 STL 1800 + L Sbjct: 316 ALL 318 Score = 32.3 bits (70), Expect = 9.9 Identities = 24/99 (24%), Positives = 40/99 (40%), Gaps = 2/99 (2%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P +IT T + G++ F+ + +P V W+ + FH Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380 L I ++G Y C+A N LG + A LK ++ N+ Sbjct: 382 LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420 >SB_24472| Best HMM Match : I-set (HMM E-Value=0) Length = 473 Score = 96.7 bits (230), Expect = 4e-19 Identities = 81/303 (26%), Positives = 130/303 (42%), Gaps = 28/303 (9%) Query: 4513 PPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571 PP ++ V+ S ++V K GT + W K+ + + D R+ ++ DGT L Sbjct: 99 PPKIVKFPSSIEVSVSSEVVSFKCKAVGTPAPQISWRKDRQPLPSDGRH-VVRPDGT--L 155 Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631 IL +D G YEC+A N AGE +A SL PQ P ++ L Sbjct: 156 DILRPQVEDEGNYECLARNDAGEQVTEA----SLRYYGRDAVPQ--LTRYPRAQVDTL-- 207 Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 EG ++ C+ G+P PT+ W K G L + + + D Y + ++ D+ Sbjct: 208 ----EGNSVTLQCRAQGRPNPTIAWAKGGTPLDVHDPHMRATSAGDLYIVGVTS---RDD 260 Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750 G Y+C A N AG V+ + +L VT P T V EG A + + P Sbjct: 261 GTYRCTASNKAGSVSASTRLVVTAAPYFITRPENT-----VELEGSTASLQCRAGGHPAP 315 Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 I W + GA +P ++ G +L + ++ D G + C+A G + L V Sbjct: 316 AIAWTKNGARLPSQDRHIVLPSGTLRILYLKHS---DQGQYECQAINVIGVKLARSFLAV 372 Query: 4811 KSK 4813 +++ Sbjct: 373 RAR 375 Score = 92.7 bits (220), Expect = 7e-18 Identities = 78/279 (27%), Positives = 110/279 (39%), Gaps = 32/279 (11%) Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483 E + G P P I W + P+ + D + S + I+ V D + Sbjct: 208 EGNSVTLQCRAQGRPNPTIAWAKGGTPL-DVHDPHMRATSAGDLYIVG-VTSRDDGTYRC 265 Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543 A N+ G+ S LVV P F +N G L + G Sbjct: 266 TASNKAGSVSASTRLVVT----------AAPYFITRPENTVELEGSTASLQCRAGGHPAP 315 Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603 + W KNG ++ R+ +L GT +L L+ D G+YEC AIN G + Sbjct: 316 AIAWTKNGARLPSQDRHIVLPS-GTLRILYLKH--SDQGQYECQAINVIG-----VKLAR 367 Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663 S A + A PP I + +D+ V GQ + C VG P P + W K + + Sbjct: 368 SFLAVR---------ARVPPSITDKPRDQNVRAGQTVNIFCVAVGAPDPVITWIKDNVQV 418 Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 F + AD+ TL I EA DEG Y+C A NS G Sbjct: 419 TEGNRFSI---ADDGTLTIREANKGDEGRYQCAARNSVG 454 Score = 90.6 bits (215), Expect = 3e-17 Identities = 107/445 (24%), Positives = 160/445 (35%), Gaps = 45/445 (10%) Query: 4377 EITRKITSTETTEIEHK-AQTQERVVEGPVKPS---KPPIFTKKMQPCRV-FEHEQARFE 4431 ++ R+ +TET H+ A+ R + PP K V E F+ Sbjct: 62 KLLRRTPNTETAATCHEPAELSGRAIVRLTPRELRCSPPKIVKFPSSIEVSVSSEVVSFK 121 Query: 4432 VEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491 + G P P I W ++ P+ P H L I + VED + +A N G Sbjct: 122 CKAVGTPAPQISWRKDRQPL---PSDGRHVVRPDGTLDILRPQVEDEGNYECLARNDAGE 178 Query: 4492 AKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551 A+L R GR VP V+ G V L + G + W K G Sbjct: 179 QVTEASL-----RYYGRDA-VPQLTRYPRAQVDTLEGNSVTLQCRAQGRPNPTIAWAKGG 232 Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611 + D+ + + L I+ +D G Y C A N AG VV+ Sbjct: 233 TPL--DVHDPHMRATSAGDLYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVT------- 283 Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQ 4670 A P I ++ + EG C+ G P P + W K G +L ++ Sbjct: 284 ---------AAPYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIV 334 Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RD 4729 + TLRI D+G Y+C A N G + L V +A P++T RD Sbjct: 335 LPSG----TLRILYLKHSDQGQYECQAINVIGVKLARSFLAV----RARVPPSITDKPRD 386 Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789 V GQ P I W+++ + E F + +G L I + D G Sbjct: 387 QNVRAGQTVNIFCVAVGAPDPVITWIKDNVQVTEGNRFSIADDG---TLTIREANKGDEG 443 Query: 4790 TFTCRATTAAGQVETSAKLVVKSKT 4814 + C A + G + L V+ K+ Sbjct: 444 RYQCAARNSVGVAMSDMILFVQGKS 468 Score = 85.8 bits (203), Expect = 8e-16 Identities = 64/207 (30%), Positives = 87/207 (42%), Gaps = 12/207 (5%) Query: 373 DTQQRETEERIEISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQ 431 D ++ TE + + PQ + + + D EG CR GRP P + W Sbjct: 175 DAGEQVTEASLRYYGRDAVPQLTRYPRAQVDTLEGNSVTLQCRAQGRPNPTIAWAKGGTP 234 Query: 432 IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491 + D ++ + +G+ L I VT D G C A NK+G + RL V AP Sbjct: 235 L-DVHDPHMRATSAGD--LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVV-----TAAP 286 Query: 492 KFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551 F+ R EG L RA G P P I W K+G +P+ + I G TL I Sbjct: 287 YFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGAR-LPSQDRHIVLPSG--TLRIL 343 Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578 K SD Y+C A NV G R+ L Sbjct: 344 YLKHSDQGQYECQAINVIGVKLARSFL 370 Score = 84.2 bits (199), Expect = 2e-15 Identities = 57/189 (30%), Positives = 87/189 (46%), Gaps = 10/189 (5%) Query: 392 PQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 P+ VK +V+ ++ F C+ G P P+++W + + + D H +V G L Sbjct: 100 PKIVKFPSSIEVSVSSEVVSFKCKAVGTPAPQISWRKDRQPLPSDGRH--VVRPDGT--L 155 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 I + D G C+ARN +GE + L ++ V R + ++ EG V L Sbjct: 156 DILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYPR-AQVDTLEGNSVTL 214 Query: 511 NARAVGTPTPRITWQKDGVPI-IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 RA G P P I W K G P+ + +P +R + A L I + D Y+CTA N A Sbjct: 215 QCRAQGRPNPTIAWAKGGTPLDVHDPHMRATS---AGDLYIVGVTSRDDGTYRCTASNKA 271 Query: 570 GSTATRARL 578 GS + RL Sbjct: 272 GSVSASTRL 280 Score = 83.8 bits (198), Expect = 3e-15 Identities = 70/278 (25%), Positives = 115/278 (41%), Gaps = 16/278 (5%) Query: 91 FEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARN 150 F+ K G P P +SW + + PL ++ +R + G + +L Q+ DEG Y C ARN Sbjct: 120 FKCKAVGTPAPQISWRKDRQPLPSDGRHVVRPD---GTLDILRPQVE--DEGNYECLARN 174 Query: 151 QYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYT 210 GE + ++ G R +T+E + Q Q R +A+ Sbjct: 175 DAGEQVTEASLRYYGRDAVPQLTRYP---RAQVDTLEGNSVTLQ--CRAQGRPNPTIAWA 229 Query: 211 NGTDHSSTDD--FKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKI 268 G D + + + V+ R+ T R + S L + P Sbjct: 230 KGGTPLDVHDPHMRATSAGDLYIVGVTSRDDGTYRCTASNKAG-SVSASTRLVVTAAPYF 288 Query: 269 AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328 +P N+ EG+ A Q + G+P P + W KNG RL + ++H ++ + TLR+ Sbjct: 289 ITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIVLPS---GTLRILYL 345 Query: 329 QKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ 366 + SD G Y A N G + +LAV + + D+ Sbjct: 346 KHSDQGQYECQAINVIGVKLARSFLAVRARVPPSITDK 383 Score = 79.4 bits (187), Expect = 7e-14 Identities = 59/180 (32%), Positives = 75/180 (41%), Gaps = 10/180 (5%) Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 AP F+ ++ EG CR G P P + W N ++ H +L SG L Sbjct: 285 APYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIVL--PSGT--L 340 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 I + SD G C A N G + L V + V P ++ NVR G+ V + Sbjct: 341 RILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR---VPPSITDKPRDQNVRAGQTVNI 397 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 AVG P P ITW KD V + I DG TL I A D YQC A+N G Sbjct: 398 FCVAVGAPDPVITWIKDNVQVTEGNRFSIADDG---TLTIREANKGDEGRYQCAARNSVG 454 Score = 66.5 bits (155), Expect = 5e-10 Identities = 66/276 (23%), Positives = 107/276 (38%), Gaps = 22/276 (7%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G + + + +G P P ++W + PL + + MR GD L I + D+G Y Sbjct: 208 EGNSVTLQCRAQGRPNPTIAWAKGGTPL-DVHDPHMRATS-AGD--LYIVGVTSRDDGTY 263 Query: 145 TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204 CTA N+ G S + + +++ +A G Sbjct: 264 RCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASLQCRAGG---------HPA 314 Query: 205 QKVAYT-NGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263 +A+T NG S D V LR + + S +Y ++ I ++ RS V Sbjct: 315 PAIAWTKNGARLPSQDRHIV--LPSGTLRILYLKHSDQGQYECQAINVIGVKLARSFLAV 372 Query: 264 S---PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320 PP I KPR+ ++ G G P P +TW K+ ++ N+ I + Sbjct: 373 RARVPPSITDKPRDQNVRAGQTVNIFCVAVGAPDPVITWIKDNVQVTEGNRFSIA---DD 429 Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356 TL +R K D G Y A N G ++ L V+ Sbjct: 430 GTLTIREANKGDEGRYQCAARNSVGVAMSDMILFVQ 465 Score = 59.7 bits (138), Expect = 6e-08 Identities = 54/200 (27%), Positives = 78/200 (39%), Gaps = 14/200 (7%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F + + E A + G P P I W + + + + T IL + Sbjct: 286 PYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIVLPSGTLRILYL 345 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 + D + A N G + L V + VPPS T ++ NV +GQ Sbjct: 346 KH---SDQGQYECQAINVIGVKLARSFLAVRAR--------VPPSITDKPRDQNVRAGQT 394 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 V + G + W+K+ +V R I + DGT T I EA D G+Y+C A N Sbjct: 395 VNIFCVAVGAPDPVITWIKDNVQVTEGNRFSIAD-DGTLT--IREANKGDEGRYQCAARN 451 Query: 4591 SAGEARCDAECVVSLPATKD 4610 S G A D V +T D Sbjct: 452 SVGVAMSDMILFVQGKSTTD 471 Score = 54.0 bits (124), Expect = 3e-06 Identities = 70/277 (25%), Positives = 102/277 (36%), Gaps = 28/277 (10%) Query: 3027 NLEDSLRKEPGQQPDDDT----GRP--PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSM 3080 N E R + G+Q + + GR P+ T + VD EG + G + Sbjct: 167 NYECLARNDAGEQVTEASLRYYGRDAVPQLTRYPRAQVDTLEGNSVTLQCRA--QGRPNP 224 Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140 I W G ++ + G L I+G + D GTY C A+NK G S +L Sbjct: 225 TIAWAKGGTPLDVHDPHMRATSAGD--LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVV 282 Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 P F T +N L +G +A +C P I W NG + R Sbjct: 283 T-----AAPYFITRPENTVEL-EGSTASLQCRA--GGHPAPAIAWTKNGARLPSQDR-HI 333 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260 V G L I Y ++ D G+Y C+A N G R+ + + + P K Sbjct: 334 VLPSG--TLRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR-------VPPSITDKP 384 Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEG 3297 R+ G P IT I+D ++ EG Sbjct: 385 RDQNVRAGQTVNIFCVAVGAPDPVITWIKDNVQVTEG 421 Score = 53.6 bits (123), Expect = 4e-06 Identities = 87/391 (22%), Positives = 146/391 (37%), Gaps = 25/391 (6%) Query: 3273 TPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR 3332 TP PPK + + V + F+ + V P ++ W + + LP R+ Sbjct: 91 TPRELRCSPPKIVKFPSSIEVSVSSEVVSFKCKAVGTPAP--QISWRKDRQPLPSDGRHV 148 Query: 3333 TFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392 D LDIL E+ G YEC+A N G T+A+L+ ++ + ++ PR Sbjct: 149 VRPDG---TLDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYPRAQVD 205 Query: 3393 GLE-KLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPN 3451 LE TL+ R + ++ KG P+ V ++ G+ + +T DD Sbjct: 206 TLEGNSVTLQCRAQGRPNPTIAWAKGGTPL-DVHDPHMRATSAGD--LYIVGVTSRDDGT 262 Query: 3452 LKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL-CRAYNNYGEAV--TTA 3508 + S+ A +R F+ + E S L CRA + A+ T Sbjct: 263 YRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKN 322 Query: 3509 SMKVQGK-RNIILES------QLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFT 3561 ++ + R+I+L S L +G + A+ + + PP T Sbjct: 323 GARLPSQDRHIVLPSGTLRILYLKHSDQGQYE-CQAINVIGVKLARSFLAVRARVPPSIT 381 Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621 P D + + + C + V + W + + G+R +D I E Sbjct: 382 DKPRDQNVRAGQTVNIFC--VAVGAPDPVITWIKDNVQVTEGNRFSIADDGTLTIREAN- 438 Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 + D G Y C A N G A L V+G+ Sbjct: 439 --KGDEGRYQCAARNSVGVAMSDMILFVQGK 467 Score = 49.2 bits (112), Expect = 8e-05 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 G P PV++W + + E N++S+ D +L I++ GDEG Y C ARN G A+ Sbjct: 403 GAPDPVITWIKDNVQVTEGNRFSI-----ADDGTLTIREANKGDEGRYQCAARNSVGVAM 457 Query: 157 CSVYIQPEG 165 + + +G Sbjct: 458 SDMILFVQG 466 Score = 48.4 bits (110), Expect = 1e-04 Identities = 35/93 (37%), Positives = 48/93 (51%), Gaps = 6/93 (6%) Query: 3828 TPPKFITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886 +PPK + S V SE V F+C+ P+ I W ++ + LPS R+ V G Sbjct: 98 SPPKIVKFPSSIEVSVSSEVVSFKCKAVGTPAPQ--ISWRKDRQPLPSDGRH-VVRPDG- 153 Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 +LDIL ED G Y C A ND GE T+A++ Sbjct: 154 -TLDILRPQVEDEGNYECLARNDAGEQVTEASL 185 Score = 47.6 bits (108), Expect = 2e-04 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 5/98 (5%) Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884 +V+ P FIT+ ++ E +CR P I W +NG LPS R+ V Sbjct: 281 VVTAAPYFITRPENTVELEGSTASLQCRAGGHPAPA--IAWTKNGARLPSQDRH-IVLPS 337 Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922 G +L ILY+ D G+Y C+A+N G ++ ++ + Sbjct: 338 G--TLRILYLKHSDQGQYECQAINVIGVKLARSFLAVR 373 Score = 47.2 bits (107), Expect = 3e-04 Identities = 52/197 (26%), Positives = 79/197 (40%), Gaps = 15/197 (7%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P F T ++ V++ EG A + G + I W NG + + R V G Sbjct: 286 PYFITRPENTVEL-EGSTASLQCRA--GGHPAPAIAWTKNGARLPSQDR-HIVLPSG--T 339 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L IL K +D G Y C+A N G +++ V + + P T + ++ GQ+ Sbjct: 340 LRILYLKHSDQGQYECQAINVIG-VKLARSFLAV---RARVPPSITDKPRDQNVRAGQTV 395 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 + C V V PD I W + + R +++D G L I D G Y C A Sbjct: 396 NIFC--VAVGAPDPVITWIKDNVQVTEGNRF-SIADDG--TLTIREANKGDEGRYQCAAR 450 Query: 3228 NKYGEDFTRATINCYGK 3244 N G + + GK Sbjct: 451 NSVGVAMSDMILFVQGK 467 Score = 46.8 bits (106), Expect = 4e-04 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 6/102 (5%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897 + V AP FIT+ +L EG +A +CR +P P + W NG L S R+ Sbjct: 280 LVVTAAPYFITRPENTVEL-EGSTASLQCRAGGHPAP--AIAWTKNGARLPSQDRHIVLP 336 Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939 L IL + D G+Y C+AIN +G ++ L V+++ Sbjct: 337 S---GTLRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375 Score = 46.4 bits (105), Expect = 6e-04 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P T +D V Q + + VG P + W+++ V + NR + D L Sbjct: 378 PSITDKPRDQNVRAGQTVNIFC--VAVGAPDPVITWIKDNVQVTEGNRFSIADDG---TL 432 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807 ++ N D G Y C A N +G A++ LFVQ K++ Sbjct: 433 TIREANKGDEGRYQCAARNSVGVAMSDMILFVQGKST 469 Score = 45.2 bits (102), Expect = 0.001 Identities = 80/353 (22%), Positives = 138/353 (39%), Gaps = 35/353 (9%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669 ++ W + +PL S R + LDI+ ED G Y C A N GE VT Sbjct: 131 QISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAGEQVTEASLRY 187 Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQ---DEVITQAPVFT-MPMKDIRVAEN 1725 + + ++ +++ A +++ LE S + AQ + I A T + + D + Sbjct: 188 YGRDAVPQLTRYPRA--QVDTLEGNSVTLQCRAQGRPNPTIAWAKGGTPLDVHDPHMRAT 245 Query: 1726 QAAH-FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDS-GTY 1783 A + + D R + AS RL ++ V E S + Sbjct: 246 SAGDLYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASL 305 Query: 1784 TCRAINELGEAVTSSTLFVQSKASLQLESQH---ESALQKIQQLE--DSSRYQRREDVEV 1838 CRA A+ + ++ A L + +H S +I L+ D +Y+ + + Sbjct: 306 QCRAGGHPAPAIA----WTKNGARLPSQDRHIVLPSGTLRILYLKHSDQGQYECQAINVI 361 Query: 1839 AVNQAPRFIT-QLNGPTKLSE---------GQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888 V A F+ + P +++ GQ+ + C PDP + W + + Sbjct: 362 GVKLARSFLAVRARVPPSITDKPRDQNVRAGQTVNIFCVAVGAPDPV--ITWIKDNVQVT 419 Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 G+R+ ++D L I D G Y C A N++G A+S + L VQ K + Sbjct: 420 EGNRFSIADD---GTLTIREANKGDEGRYQCAARNSVGVAMSDMILFVQGKST 469 Score = 44.8 bits (101), Expect = 0.002 Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 7/110 (6%) Query: 2791 IHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKA 2850 + F+C + P +I W + +PLPS R+ D + LDI ED G Y C A Sbjct: 118 VSFKCKAVGT--PAPQISWRKDRQPLPSDGRHVVRPDGT---LDILRPQVEDEGNYECLA 172 Query: 2851 TNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAG-LEAVEQAEEARLAKGR 2899 N G T SLR G + T++P+ + LE + R A+GR Sbjct: 173 RNDAGEQVTEASLRYYGRDAVPQLTRYPRAQVDTLEGNSVTLQCR-AQGR 221 Score = 44.0 bits (99), Expect = 0.003 Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 5/99 (5%) Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208 P+ +IE + F+C V P +I W + QP+ R V G Sbjct: 100 PKIVKFPSSIEVSVSSEVVSFKCKAVGTPAP--QISWRKDRQPLPSDGR-HVVRPDG--T 154 Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGV 3247 LDI Q D G Y C A N GE T A++ YG+ V Sbjct: 155 LDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAV 193 Score = 44.0 bits (99), Expect = 0.003 Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 13/138 (9%) Query: 2885 EAVEQAEEARLAKGRRPSVPD-TEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDL 2943 +A EQ EA L R +VP T YP+ A+ +EG + L+ + + + +P Sbjct: 175 DAGEQVTEASLRYYGRDAVPQLTRYPR--------AQVDTLEGNSVTLQCRAQGRPNPT- 225 Query: 2944 KIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYC 3003 I W G L+ + G L +V V RD G Y C A NK G S+ + Sbjct: 226 -IAWAKGGTPLDVHDPHMRATSAG--DLYIVGVTSRDDGTYRCTASNKAGSVSASTRLVV 282 Query: 3004 TSKDNLIERTQHPKGTEG 3021 T+ I R ++ EG Sbjct: 283 TAAPYFITRPENTVELEG 300 Score = 43.2 bits (97), Expect = 0.005 Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 14/148 (9%) Query: 3548 LTPEAESGNPPEFTTTPSDLILSENSSA-HFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606 LTP +PP+ PS + +S +S F+C+ V + ++ W + +PL + R Sbjct: 90 LTPRELRCSPPKIVKFPSSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGR- 146 Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666 + G L+I D G Y C A N GE L+ GR + PQL + + Sbjct: 147 HVVRPDG--TLDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAV---PQLTRYPR 201 Query: 3667 SGTESIQKLEETLHKREEITIEDEKPNP 3694 + ++++ TL R + +PNP Sbjct: 202 AQVDTLEGNSVTLQCRAQ-----GRPNP 224 Score = 42.7 bits (96), Expect = 0.007 Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 6/113 (5%) Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD 1366 V Q ++ RA ++T+EG +V L+CR Q G + W G P+ A Sbjct: 193 VPQLTRYPRA--QVDTLEGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG 248 Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLE 1419 L ++ V D G Y C A+N+ G S L V A I ++ LE Sbjct: 249 --DLYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299 Score = 42.7 bits (96), Expect = 0.007 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P FI ++ +EG + R G P I W KNG + + R + G +L Sbjct: 286 PYFITRPENTVELEGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDRHI-VLPSG--TL 340 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 +L L D G+Y C+A++ GV ++ L V R Sbjct: 341 RILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/110 (24%), Positives = 45/110 (40%), Gaps = 4/110 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P+ P++ + +EG V +C+ + N + W K G P+ + G Sbjct: 194 PQLTRYPRAQVDTLEGNSVTLQCRAQG--RPNPTIAWAKGGTPLDVHDPHMRATSAG--D 249 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLE 1553 L I+ + + D G Y C A N G+ S RL + + +N LE Sbjct: 250 LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299 Score = 41.9 bits (94), Expect = 0.012 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 4/95 (4%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P+ T + +D EG V CR + G P I W G P G Sbjct: 194 PQLTRYPRAQVDTLEGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--D 249 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789 L I + +RD G Y C A+NK GS + + ++ +A Sbjct: 250 LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTA 284 Score = 40.7 bits (91), Expect = 0.028 Identities = 31/125 (24%), Positives = 48/125 (38%), Gaps = 8/125 (6%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L+IL + D G Y C A N G+ L + P+ T + + +G S Sbjct: 155 LDILRPQVEDEGNYECLARNDAGEQVTEASLRYY--GRDAVPQLTRYPRAQVDTLEGNSV 212 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMR-HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226 +C P+ I W G P+ H ++ S ++ + + D G Y C A Sbjct: 213 TLQCRA--QGRPNPTIAWAKGGTPLDVHDPHMRATSAGDLYIVGVT---SRDDGTYRCTA 267 Query: 3227 YNKYG 3231 NK G Sbjct: 268 SNKAG 272 Score = 40.3 bits (90), Expect = 0.037 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 5/99 (5%) Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175 +S+E + F+C+ + P I W + Q + + R+ D LDIL Sbjct: 107 SSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQ 161 Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214 ED G Y C A N GE V +L+ G + T++P Sbjct: 162 VEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYP 200 Score = 40.3 bits (90), Expect = 0.037 Identities = 32/117 (27%), Positives = 46/117 (39%), Gaps = 5/117 (4%) Query: 3558 PEFTTTP-SDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 P+ T P + + E +S +CR + + W G PL G Sbjct: 194 PQLTRYPRAQVDTLEGNSVTLQCRA--QGRPNPTIAWAKGGTPLDVHDPHMRATSAGD-- 249 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ 3673 L I GV RD G Y C A+N+ G + S +L V I P+ + T S+Q Sbjct: 250 LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASLQ 306 Score = 39.5 bits (88), Expect = 0.065 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 4/106 (3%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP+ + S+ ++ + + VG P +I W K+ Q + + R + G + Sbjct: 99 PPKIVKFPSSIEVSVSSEV-VSFKCKAVGTPAPQISWRKDRQPLPSDGRHV-VRPDG--T 154 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741 LD+L ++D G Y C A + G T+A L R + + +++P Sbjct: 155 LDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYP 200 Score = 39.5 bits (88), Expect = 0.065 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Query: 797 VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856 V P ++ W KD +P+ + R + G +L+I+ + ED G+Y A N GE ++ Sbjct: 125 VGTPAPQISWRKDRQPLPSDGRHV-VRPDG--TLDILRPQVEDEGNYECLARNDAGEQVT 181 Query: 857 TASIRVAARSTV 868 AS+R R V Sbjct: 182 EASLRYYGRDAV 193 Score = 39.5 bits (88), Expect = 0.065 Identities = 16/47 (34%), Positives = 23/47 (48%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY 4157 P F++ P+ EG A CR GHP P + W NG + + R+ Sbjct: 286 PYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRH 332 Score = 39.5 bits (88), Expect = 0.065 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 5/72 (6%) Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446 N++ GQT + C + VG P + W ++ + + +R + D ++TI DE Sbjct: 388 NVRAGQTVNIFC--VAVGAPDPVITWIKDNVQVTEGNRFSIADDG---TLTIREANKGDE 442 Query: 2447 GVYMCRASNLLG 2458 G Y C A N +G Sbjct: 443 GRYQCAARNSVG 454 Score = 39.1 bits (87), Expect = 0.086 Identities = 16/58 (27%), Positives = 25/58 (43%) Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163 +AR PP P V G+ C G P P + W+ + + G+R+ + DG Sbjct: 373 RARVPPSITDKPRDQNVRAGQTVNIFCVAVGAPDPVITWIKDNVQVTEGNRFSIADDG 430 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET 722 VG P I W+K+ + +RF SI G +L + N D G Y C A ++ GVA + Sbjct: 402 VGAPDPVITWIKDNVQVTEGNRF-SIADDG--TLTIREANKGDEGRYQCAARNSVGVAMS 458 Query: 723 KAVLHVTPRATIERT 737 +L V ++T + T Sbjct: 459 DMILFVQGKSTTDFT 473 Score = 38.7 bits (86), Expect = 0.11 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 7/102 (6%) Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPV-HFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743 +T + + +PP+ V+ +I+V V F C+ VG P +I W + +P + R Sbjct: 90 LTPRELRCSPPKI-VKFPSSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGR 146 Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 H + G LDI D G Y C A N G T A + Sbjct: 147 -HVVRPDG--TLDILRPQVEDEGNYECLARNDAGEQVTEASL 185 Score = 38.3 bits (85), Expect = 0.15 Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 4/96 (4%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 EG S +CR + P+P + W G L + + G L I+ V D G Y Sbjct: 208 EGNSVTLQCRAQGRPNPT--IAWAKGGTPLDVHDPHMRATSAG--DLYIVGVTSRDDGTY 263 Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953 C A N G +S RL V + I ++ LE Sbjct: 264 RCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 4108 RC-PPVFVSLPDAVTVE-EGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165 RC PP V P ++ V E F C+ G P P++ W + + + R+ + DG Sbjct: 96 RCSPPKIVKFPSSIEVSVSSEVVSFKCKAVGTPAPQISWRKDRQPLPSDGRHVVRPDGT- 154 Query: 4166 HFDIPKTRQYDTGKIEVI 4183 DI + + D G E + Sbjct: 155 -LDILRPQVEDEGNYECL 171 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Query: 2004 VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063 V P ++ W + +P+ R D LDIL ED G Y C A N GE VT Sbjct: 125 VGTPAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAGEQVT 181 Query: 2064 TSSVK 2068 +S++ Sbjct: 182 EASLR 186 Score = 37.5 bits (83), Expect = 0.26 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P+ I W K+ V +T G R S D G TL+I D G Y C A N +G A+S Sbjct: 405 PDPVITWIKDNVQVTEGNRF-SIADDG--TLTIREANKGDEGRYQCAARNSVGVAMSDMI 461 Query: 2732 IKIEDR 2737 + ++ + Sbjct: 462 LFVQGK 467 Score = 37.1 bits (82), Expect = 0.35 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 5/83 (6%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P+ V P SIE + + V F+CK V ++ W K+ QP+ R + G Sbjct: 100 PKIVKFPSSIEVSVSSEVVSFKCK--AVGTPAPQISWRKDRQPLPSDGR-HVVRPDG--T 154 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVG 1526 LDI+ ED G Y C A N G Sbjct: 155 LDILRPQVEDEGNYECLARNDAG 177 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 7/99 (7%) Query: 1864 YECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923 ++C+ P P ++ W + + L S R+ D LDIL ED G Y C A N Sbjct: 120 FKCKAVGTPAP--QISWRKDRQPLPSDGRHVVRPD---GTLDILRPQVEDEGNYECLARN 174 Query: 1924 NLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962 + G+ V+ L ++++ + +++ A ++ LE +S Sbjct: 175 DAGEQVTEASLRYYGRDAVPQLTRYPRA--QVDTLEGNS 211 Score = 36.7 bits (81), Expect = 0.46 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796 VG P ++ W ++ P+ + R D L++ ED G Y C A N+ GE VT Sbjct: 125 VGTPAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAGEQVT 181 Query: 1797 SSTL 1800 ++L Sbjct: 182 EASL 185 Score = 36.7 bits (81), Expect = 0.46 Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 8/115 (6%) Query: 2625 AMNKVPEMFVDTG--VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG 2682 A NK + T V AP F T ++ +L EG L+ + P I W KNG Sbjct: 267 ASNKAGSVSASTRLVVTAAPYFITRPENTVEL-EGSTASLQCRAGGHPAP--AIAWTKNG 323 Query: 2683 VTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 L + R G TL I L++ D G Y C+A N++G ++ + + + R Sbjct: 324 ARLPSQDR-HIVLPSG--TLRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375 Score = 36.7 bits (81), Expect = 0.46 Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 9/103 (8%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK--PIKTGHRFRPA 1362 + V AP F N +EG+ L+CR G + W NG P + H P+ Sbjct: 280 LVVTAAPYFITRPENTVELEGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDRHIVLPS 337 Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 L +L + D G Y CQA N +G + L V A+ Sbjct: 338 G-----TLRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375 Score = 36.3 bits (80), Expect = 0.61 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 10/108 (9%) Query: 1311 PQFSRALHNIE-TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG--HRFRPAYEFDY 1367 P+ + +IE +V V +C+ VG ++ W + +P+ + H RP Sbjct: 100 PKIVKFPSSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGRHVVRPDG---- 153 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415 LD+L ED G Y C A N GE VT +LR + + +++P Sbjct: 154 -TLDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYP 200 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 4/96 (4%) Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250 EG ++ L+CR + G P + W G + V G L I+ TS D G Y Sbjct: 208 EGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--DLYIVGVTSRDDGTY 263 Query: 1251 TVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286 A N GS S + V +T +N +E Sbjct: 264 RCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 6/83 (7%) Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301 P F+T T + EG TA +C+ P I + NG L S R HI G + Sbjct: 286 PYFITRPENTVEL-EGSTASLQCRAGG--HPAPAIAWTKNGARLPSQDR-HIVLPSG--T 339 Query: 2302 LDIQHCVPEDAGEYSVKAINALG 2324 L I + D G+Y +AIN +G Sbjct: 340 LRILYLKHSDQGQYECQAINVIG 362 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 6/92 (6%) Query: 1982 KPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILY 2041 KP ++ V G V++ DP + W + V +G+RF D L I Sbjct: 383 KP-RDQNVRAGQTVNIFCVAVGAPDPV--ITWIKDNVQVTEGNRFSIADDG---TLTIRE 436 Query: 2042 AYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 A D G Y C A N+VG A++ + V KS Sbjct: 437 ANKGDEGRYQCAARNSVGVAMSDMILFVQGKS 468 Score = 35.9 bits (79), Expect = 0.80 Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 7/121 (5%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG+++ +C + +PT I W PL + S L I D G Y Sbjct: 208 EGNSVTLQCRAQGRPNPT--IAWAKGGTPLDVHDPHMRAT--SAGDLYIVGVTSRDDGTY 263 Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDT 2906 C A+N GS + S L T YF T+ P+ LE + + R P++ T Sbjct: 264 RCTASNKAGSVSASTRLVVTAAP--YFITR-PENTVELEGSTASLQCRAGGHPAPAIAWT 320 Query: 2907 E 2907 + Sbjct: 321 K 321 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 6/96 (6%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P FI ++ EL EG A + + P + W K+G + + R + G + Sbjct: 286 PYFITRPENTVEL-EGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDRHI-VLPSG--T 339 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 L I++L+ D G Y +A+N +G ++ + + V AR Sbjct: 340 LRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 5/85 (5%) Query: 2119 ENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAED 2178 +N++ G + C DP +T W + ++ G+R+ D L I D Sbjct: 387 QNVRAGQTVNIFCVAVGAPDPVIT--WIKDNVQVTEGNRFSIADDG---TLTIREANKGD 441 Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAG 2203 G Y C A N +G A++ L V G Sbjct: 442 EGRYQCAARNSVGVAMSDMILFVQG 466 Score = 35.1 bits (77), Expect = 1.4 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 5/108 (4%) Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031 PP+ V S V E F+C+ VG P ++ W + +PL R D G + Sbjct: 99 PPKIVKFPSSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGRHVVRPD-GTL 155 Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079 + V ED G Y C A N G T+A ++ G+ + ++ P+ Sbjct: 156 DILRPQV--EDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYPR 201 Score = 35.1 bits (77), Expect = 1.4 Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 4/110 (3%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P+ + Q+ EG + R + G + W K G P++ + G Sbjct: 194 PQLTRYPRAQVDTLEGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--D 249 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLE 1018 L I VT D G Y C A N G + S L + I ++ LE Sbjct: 250 LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299 Score = 35.1 bits (77), Expect = 1.4 Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 6/83 (7%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F+T + L EG A +CR P I W NG ++ + R+ Sbjct: 286 PYFITRPENTVEL-EGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDRHIVLPSG---T 339 Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191 L ILY D G Y C+A N +G Sbjct: 340 LRILYLKHSDQGQYECQAINVIG 362 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 6/87 (6%) Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499 VT P F+TRP++ +EG +C+ + W KNG + R + Sbjct: 282 VTAAPYFITRPENTVE-LEGSTASLQCRAGGHPAP--AIAWTKNGARLPSQDRHIVLPSG 338 Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVG 1526 L I+ L D G Y C+A+N++G Sbjct: 339 ---TLRILYLKHSDQGQYECQAINVIG 362 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P F +N +G A + + G+P P ++WT+ A L +++ + +G +L Sbjct: 286 PYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIVL---PSG--TL 340 Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161 I + D+G+Y C A N G + ++ Sbjct: 341 RILYLKHSDQGQYECQAINVIGVKLARSFL 370 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 6/99 (6%) Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT-GARLKSTF 2695 G P T + ++ +EG V L+ + + R PN I W K G L +++T Sbjct: 189 GRDAVPQLTRYPRAQVDTLEGNSVTLQCRAQGR--PNPTIAWAKGGTPLDVHDPHMRATS 246 Query: 2696 DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L + + S D G Y C A+N G ++ + + Sbjct: 247 AGDLYIVGVTSR---DDGTYRCTASNKAGSVSASTRLVV 282 Score = 33.9 bits (74), Expect = 3.2 Identities = 30/109 (27%), Positives = 41/109 (37%), Gaps = 7/109 (6%) Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182 EG+ +CR + P+ TI W G + + G L I+ + D GTY Sbjct: 208 EGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--DLYIVGVTSRDDGTY 263 Query: 2183 MCKATNKLGEAVNTCTLKVAGHRNIIL---DTQHPNGLEKIRQLEAQGH 2228 C A+NK G + L V I +T G Q A GH Sbjct: 264 RCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASLQCRAGGH 312 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 3/77 (3%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 P +I W + + L R + D TLD++ D G Y C A N GE T ++ Sbjct: 128 PAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAGEQVTEAS 184 Query: 3001 VYCTSKDNLIERTQHPK 3017 + +D + + T++P+ Sbjct: 185 LRYYGRDAVPQLTRYPR 201 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 PD I W + + +G+RF + D TL + + + D G Y C A N G A + Sbjct: 405 PDPVITWIKDNVQVTEGNRFSIADDG---TLTIREANKGDEGRYQCAARNSVGVAMSDMI 461 Query: 3001 VYCTSK 3006 ++ K Sbjct: 462 LFVQGK 467 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 6/83 (7%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P F ++ +++ EG CR G P I W NG + R H + G Sbjct: 286 PYFITRPENTVEL-EGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDR-HIVLPSG--T 339 Query: 3755 LDIDYIYARDAGEYTCRATNKWG 3777 L I Y+ D G+Y C+A N G Sbjct: 340 LRILYLKHSDQGQYECQAINVIG 362 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 5/97 (5%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637 P T ++ ++ GQ + + D + W +N + G+RF+ ++ L Sbjct: 378 PSITDKPRDQNVRAGQTVNIFCVAVGAPDPV--ITWIKDNVQVTEGNRFSIADDG---TL 432 Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674 I D G Y C A N++G A++ I V K + Sbjct: 433 TIREANKGDEGRYQCAARNSVGVAMSDMILFVQGKST 469 Score = 33.1 bits (72), Expect = 5.7 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248 V G+ +++ C +G P + W + VT G+RF + D G L I A D G Sbjct: 389 VRAGQTVNIFC--VAVGAPDPVITWIKDNVQVTEGNRF-SIADDG--TLTIREANKGDEG 443 Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERS 1273 Y A N +G A + I+ V +S Sbjct: 444 RYQCAARNSVGVAMSDMILFVQGKS 468 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 932 RLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991 + + +G ++ W KD +P+ + R + L I V D G+Y C A N G Sbjct: 121 KCKAVGTPAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAG 177 Query: 992 QATTSANLTIVTKKDIIAESQHP 1014 + T A+L + + +++P Sbjct: 178 EQVTEASLRYYGRDAVPQLTRYP 200 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 4/88 (4%) Query: 642 PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSL 701 P V +EG + + R + G P I W K G ++ G L ++ + Sbjct: 200 PRAQVDTLEGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--DLYIVGV 255 Query: 702 NIQDSGEYTCRAVSATGVAETKAVLHVT 729 +D G Y C A + G L VT Sbjct: 256 TSRDDGTYRCTASNKAGSVSASTRLVVT 283 Score = 32.7 bits (71), Expect = 7.5 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 8/89 (8%) Query: 2371 VTRQRPVF-TQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH 2429 V P F T+P ++ EG TA CR G P + W +N + R Sbjct: 281 VVTAAPYFITRPENTVE--LEGSTASLQCRA--GGHPAPAIAWTKNGARLPSQDRHIVLP 336 Query: 2430 DFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 ++ I +++ D+G Y C+A N++G Sbjct: 337 SG---TLRILYLKHSDQGQYECQAINVIG 362 Score = 32.3 bits (70), Expect = 9.9 Identities = 24/88 (27%), Positives = 34/88 (38%), Gaps = 5/88 (5%) Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845 + G ++ C + DP I W +N + G R+ D + L I + D G Sbjct: 390 RAGQTVNIFCVAVGAPDPV--ITWIKDNVQVTEGNRFSIADDGT---LTIREANKGDEGR 444 Query: 2846 YTCKATNSKGSATTSGSLRCTGDKNIYF 2873 Y C A NS G A + L G F Sbjct: 445 YQCAARNSVGVAMSDMILFVQGKSTTDF 472 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 3/58 (5%) Query: 2533 VPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 V VG P W + V++ G+RF D TL I D G Y C A N G Sbjct: 400 VAVGAPDPVITWIKDNVQVTEGNRFSIADD---GTLTIREANKGDEGRYQCAARNSVG 454 >SB_33342| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1189 Score = 96.3 bits (229), Expect = 5e-19 Identities = 100/408 (24%), Positives = 159/408 (38%), Gaps = 30/408 (7%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F ++ V ++ QA + G P P I W + + D + S+L I Sbjct: 84 PFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKILPDGSLLFI 143 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSAN-LVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527 +E + N A N L E + R + + S +T + V V Sbjct: 144 T---IEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGLSSKITIEPVTSQVIF 200 Query: 4528 GQLVRLDTKVTGTKPIDVY-WL---KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583 G + RL KV + P + W K+G ++ +K+ G + I D G+ Sbjct: 201 GDVARLFCKVRHSLPDSIIQWKFKQKDGSEIALTPSSKVTLLPGG-VIQIRNVQLDDGGE 259 Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643 Y+C A N + R + +L D+ P+ ++ P + +G+ Sbjct: 260 YKCTAENPVTK-RTHSSAYATLTVIPDRGNPRRADF-----VVTPPSRVVAIKGKHTVLE 313 Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 C + G P P V+WYK +++ Y E L I + P D G YKC A +S + Sbjct: 314 CAVKGSPKPVVKWYKNGQIVT---YDSRVTIIGESNLEIMQVVPSDAGTYKCEATSSGSQ 370 Query: 4704 -VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 V+ +LKV P + LRD Y G F KP + W + G I Sbjct: 371 PVSAETRLKVNYPPVF-----IKRLRDHNAYTGSVVTFNCTADGNPKPNVYWSKNGYKIG 425 Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 T DF + +G L + + D G + C AT + G ++ SA+L V Sbjct: 426 ST-DFTKVGDG---FLKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469 Score = 70.1 bits (164), Expect = 4e-11 Identities = 53/175 (30%), Positives = 71/175 (40%), Gaps = 14/175 (8%) Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464 +GK T +C V G P P V W+ N + + D I+ G L I V SD+G Sbjct: 306 KGKHTVLECAVKGSPKPVVKWYKNGQIVTYDSRVTII----GESNLEIMQVVPSDAGTYK 361 Query: 465 CVARNKSGE-TAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523 C A + + + + RL V P F++R N G V N A G P P + Sbjct: 362 CEATSSGSQPVSAETRLKVN-----YPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVY 416 Query: 524 WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 W K+G I ++ G L + SD YQC A N GS A L Sbjct: 417 WSKNGYKIGSTDFTKV----GDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAEL 467 Score = 54.4 bits (125), Expect = 2e-06 Identities = 50/192 (26%), Positives = 79/192 (41%), Gaps = 9/192 (4%) Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI--NDRQIRDDYNHKIL 441 EI+ LAP F++ D V + + CR G P P ++W ND + D KIL Sbjct: 76 EITSSQLAPFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKIL 135 Query: 442 VNESGNH-ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFST 499 + S + T + D G CVA ++ ++ R +++ + ++ K T Sbjct: 136 PDGSLLFITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGLSSKITIEPVT 195 Query: 500 LNVREGEPVVLNARA-VGTPTPRITW---QKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555 V G+ L + P I W QKDG I P ++ G + I + Sbjct: 196 SQVIFGDVARLFCKVRHSLPDSIIQWKFKQKDGSEIALTPSSKVTLLPG-GVIQIRNVQL 254 Query: 556 SDAAWYQCTAQN 567 D Y+CTA+N Sbjct: 255 DDGGEYKCTAEN 266 Score = 53.6 bits (123), Expect = 4e-06 Identities = 62/244 (25%), Positives = 95/244 (38%), Gaps = 18/244 (7%) Query: 3040 PDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRT 3099 PD R +F V +G+ E ++ G V++W+ NG+ + R+ Sbjct: 284 PDRGNPRRADFVVTPPSRVVAIKGKHTVLECAV--KGSPKPVVKWYKNGQIVTYDSRVTI 341 Query: 3100 VYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159 + G LEI+ +D+GTY C AT+ G +S + P F +++ Sbjct: 342 I---GESNLEIMQVVPSDAGTYKCEATSS-GSQPVSAETRL---KVNYPPVFIKRLRD-H 393 Query: 3160 GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219 G F CT +P + W NG + ST V D GF L + D Sbjct: 394 NAYTGSVVTFNCTA--DGNPKPNVYWSKNGYKI-GSTDFTKVGD-GF--LKVEDLLPSDM 447 Query: 3220 GEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA 3279 G Y C A N G A ++ Y K GV L + + + A+ L TP + Sbjct: 448 GMYQCFATNSLGSIQASAELSVY-KTGVPLPTTRLPTTAQ-TPTTILPPTTTPTPPPTTT 505 Query: 3280 EPPK 3283 EP + Sbjct: 506 EPQR 509 Score = 51.6 bits (118), Expect = 2e-05 Identities = 57/243 (23%), Positives = 92/243 (37%), Gaps = 41/243 (16%) Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299 +TKR + ++ DR P + P +G + + G+P+P V W Sbjct: 268 VTKRTHSSAYATLTVIPDRG-NPRRADFVVTPPSRVVAIKGKHTVLECAVKGSPKPVVKW 326 Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359 +KNGQ + ++ II N L + SD+G Y C TS Sbjct: 327 YKNGQIVTYDSRVTIIGESN---LEIMQVVPSDAGTYK--------CEATS--------- 366 Query: 360 ESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRP 419 + +Q E R++++ P F+K +D + G + F+C G P Sbjct: 367 ------------SGSQPVSAETRLKVN---YPPVFIKRLRDHNAYTGSVVTFNCTADGNP 411 Query: 420 YPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCR 479 P V W N +I K+ G+ L + ++ SD G+ C A N G Sbjct: 412 KPNVYWSKNGYKIGSTDFTKV-----GDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAE 466 Query: 480 LNV 482 L+V Sbjct: 467 LSV 469 Score = 47.2 bits (107), Expect = 3e-04 Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 6/103 (5%) Query: 470 KSGETAFQCR-LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528 + GE + + + +N I Q+ AP F+E S + V++ +L RA G P+PRI+W+ +G Sbjct: 63 EKGEISLRGKYVNEITSSQL-APFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNG 121 Query: 529 --VPIIPNPELRIHTDGGASTLDIPRAKAS--DAAWYQCTAQN 567 + + + +I DG + I K+S D YQC A + Sbjct: 122 NDLNLAGDKRRKILPDGSLLFITIEHTKSSKPDEGNYQCVASS 164 Score = 46.0 bits (104), Expect = 8e-04 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 13/112 (11%) Query: 3820 PKEEPIVSTPPKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878 P+ V TPP + IK HTV EC V K PK ++WY+NG+++ R Sbjct: 289 PRRADFVVTPPSRVVAIKGKHTV-------LECAV--KGSPKPVVKWYKNGQIVTYDSR- 338 Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930 V +G +L+I+ V D+G Y C A + + + T P + ++ Sbjct: 339 --VTIIGESNLEIMQVVPSDAGTYKCEATSSGSQPVSAETRLKVNYPPVFIK 388 Score = 45.6 bits (103), Expect = 0.001 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 6/99 (6%) Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492 T I D + FV P S I+G+H EC ++ V+W+KNGQ VT R Sbjct: 281 TVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAVKG--SPKPVVKWYKNGQIVTYDSR 338 Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531 I G L+I+ ++ D+G Y C A + G+ VS Sbjct: 339 VTII---GESNLEIMQVVPSDAGTYKCEATS-SGSQPVS 373 Score = 45.2 bits (102), Expect = 0.001 Identities = 38/127 (29%), Positives = 57/127 (44%), Gaps = 9/127 (7%) Query: 3541 YSGTVDTLTPEAESGNP--PEFTTTP-SDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597 +S TLT + GNP +F TP S ++ + EC + V+W+ NG Sbjct: 273 HSSAYATLTVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAV--KGSPKPVVKWYKNG 330 Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657 + + SRV I + LEI V DAG Y C+AT+ G VS + ++K + Sbjct: 331 QIVTYDSRVTIIGESN---LEIMQVVPSDAGTYKCEATS-SGSQPVSAETRLKVNYPPVF 386 Query: 3658 EPQLPSH 3664 +L H Sbjct: 387 IKRLRDH 393 Score = 44.0 bits (99), Expect = 0.003 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 6/144 (4%) Query: 3780 TTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSH 3839 T +++T + ++ + +P K + G + + V+ PP FI +++ H Sbjct: 334 TYDSRVTIIGESNLEIMQVVPSDAGTYKCEATSSGSQPVSAETRLKVNYPPVFIKRLRDH 393 Query: 3840 TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899 V F C + +PK + W +NG + S + V D GF+ ++ L D Sbjct: 394 NAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKIGSTD-FTKVGD-GFLKVEDL--LPSDM 447 Query: 3900 GEYICRAVNDFGEDFTKATISCKK 3923 G Y C A N G A +S K Sbjct: 448 GMYQCFATNSLGSIQASAELSVYK 471 Score = 43.6 bits (98), Expect = 0.004 Identities = 31/104 (29%), Positives = 50/104 (48%), Gaps = 9/104 (8%) Query: 640 IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDML 699 + P V A++G E ++ G P ++W KNGQ + SR T I G +L+++ Sbjct: 296 VTPPSRVVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTII---GESNLEIM 350 Query: 700 SLNIQDSGEYTCRAVSATG---VAETKAVLHVTPRATIERTSQH 740 + D+G Y C A S+ AET+ ++ P I+R H Sbjct: 351 QVVPSDAGTYKCEATSSGSQPVSAETRLKVNYPP-VFIKRLRDH 393 Score = 43.6 bits (98), Expect = 0.004 Identities = 41/147 (27%), Positives = 67/147 (45%), Gaps = 14/147 (9%) Query: 3642 TVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDE-KPN-PPRFTV 3699 T ++ + G + + +PS +GT K E T + ++ E K N PP F Sbjct: 334 TYDSRVTIIGESNLEIMQVVPSD--AGT---YKCEATSSGSQPVSAETRLKVNYPPVFIK 388 Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759 ++D+ + G V F+C + G+P + W NG + GS T GF L ++ Sbjct: 389 RLRDH-NAYTGSVVTFNCTAD--GNPKPNVYWSKNG--YKIGSTDFTKVGDGF--LKVED 441 Query: 3760 IYARDAGEYTCRATNKWGSATTTAKIT 3786 + D G Y C ATN GS +A+++ Sbjct: 442 LLPSDMGMYQCFATNSLGSIQASAELS 468 Score = 43.6 bits (98), Expect = 0.004 Identities = 34/114 (29%), Positives = 51/114 (44%), Gaps = 6/114 (5%) Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691 +V PP FI L+ A G + F + G+P + W KNG I S+ FT + Sbjct: 379 KVNYPPVFIKRLRDHNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI-GSTDFTKVGD- 434 Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745 G++ ++ L D G Y C A ++ G + A L V T++ P T Q Sbjct: 435 GFLKVE--DLLPSDMGMYQCFATNSLGSIQASAELSVYKTGVPLPTTRLPTTAQ 486 Score = 41.9 bits (94), Expect = 0.012 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 5/102 (4%) Query: 3951 KKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWF 4010 K+ S Y T + D + FV S+ ++ + T EC A G P V+W+ Sbjct: 270 KRTHSSAYATLTVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLEC--AVKGSPKPVVKWY 327 Query: 4011 FNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATN 4052 NG+ + + +R T I + M V P D+G Y C AT+ Sbjct: 328 KNGQIVTYDSRVTIIGESNLEIMQ---VVPSDAGTYKCEATS 366 Score = 41.1 bits (92), Expect = 0.021 Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN--TIVNGSRYK 4158 V E + ++ P F+ P + V++ A CR G P PR+ W NGN + R K Sbjct: 74 VNEITSSQLAPFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRK 133 Query: 4159 LTYDGMYHF 4167 + DG F Sbjct: 134 ILPDGSLLF 142 Score = 41.1 bits (92), Expect = 0.021 Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 12/112 (10%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL-LTGSRVKTINDFG--- 3613 P F PSD+++ +N A +CR + S R+ W HNG L L G + + I G Sbjct: 84 PFFLEEPSDIVVKKNRQALLKCRAGGL--PSPRISWRHNGNDLNLAGDKRRKILPDGSLL 141 Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVS-----CKLQVKGRQG-IILEP 3659 F+ +E + D G Y C A+++ KLQV G I +EP Sbjct: 142 FITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGLSSKITIEP 193 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 11/125 (8%) Query: 3107 VLEILGTKTTDSGTYSCRATN---KWGQAEISVKLECV-DKSKGQKPRF-TTHIQNIEGL 3161 V++I + D G Y C A N K + L + D+ ++ F T + + Sbjct: 246 VIQIRNVQLDDGGEYKCTAENPVTKRTHSSAYATLTVIPDRGNPRRADFVVTPPSRVVAI 305 Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221 K G+ EC V P ++WY NGQ + + +R+ + + ++ + + D+G Sbjct: 306 K-GKHTVLECAV--KGSPKPVVKWYKNGQIVTYDSRVTIIGESNLEIMQVVPS---DAGT 359 Query: 3222 YVCRA 3226 Y C A Sbjct: 360 YKCEA 364 Score = 40.7 bits (91), Expect = 0.028 Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%) Query: 1721 RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDS 1780 RV + H G PK V+W +NG + +R+T + G L + V P D+ Sbjct: 301 RVVAIKGKHTVLECAVKGSPKPVVKWYKNGQIVTYDSRVTII---GESNLEIMQVVPSDA 357 Query: 1781 GTYTCRAINELGEAVTSST 1799 GTY C A + + V++ T Sbjct: 358 GTYKCEATSSGSQPVSAET 376 Score = 40.7 bits (91), Expect = 0.028 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 4/99 (4%) Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461 E +K + PP+F K+++ + F DG P P + W + + I S DF T Sbjct: 375 ETRLKVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYWSKNGYKI-GSTDF---T 430 Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500 L + + D ++ A N G+ + SA L V Sbjct: 431 KVGDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469 Score = 40.3 bits (90), Expect = 0.037 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 6/95 (6%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 +G+ EC ++ P P V+WY NG+++ R G + L+I+ V D+G Y Sbjct: 306 KGKHTVLECAVKGSPKPV--VKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTY 360 Query: 1918 TCKAINNLGQAVSS-IRLNVQSKESIIRDSQHESA 1951 C+A ++ Q VS+ RL V I+ + +A Sbjct: 361 KCEATSSGSQPVSAETRLKVNYPPVFIKRLRDHNA 395 Score = 39.9 bits (89), Expect = 0.049 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 8/102 (7%) Query: 3685 ITIEDEKPNPPR--FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742 +T+ ++ NP R F V + +G +C V+ G P + W+ NG+ S Sbjct: 280 LTVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDS 337 Query: 3743 RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784 RV + + L+I + DAG Y C AT+ GS +A+ Sbjct: 338 RVTIIGESN---LEIMQVVPSDAGTYKCEATSS-GSQPVSAE 375 Score = 39.9 bits (89), Expect = 0.049 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Query: 786 RNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTV 845 + H + P V+WYK+G+ +T SR+T I G +L IM + DAG+Y Sbjct: 306 KGKHTVLECAVKGSPKPVVKWYKNGQIVTYDSRVTII---GESNLEIMQVVPSDAGTYKC 362 Query: 846 RAVNKLGEAIS 856 A + + +S Sbjct: 363 EATSSGSQPVS 373 Score = 39.5 bits (88), Expect = 0.065 Identities = 39/150 (26%), Positives = 60/150 (40%), Gaps = 8/150 (5%) Query: 2053 KATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFL 2112 K T G + +V++D G Y T + K+ Y I + +R F+ Sbjct: 238 KVTLLPGGVIQIRNVQLD-DGGEYKCTAENPVTKRTHS-SAYATLTVIPDRGNPRRADFV 295 Query: 2113 TALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDIL 2172 S +G EC V+ P + W+ NGQ + R G L+I+ Sbjct: 296 VTPPSRVVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTI---IGESNLEIM 350 Query: 2173 YTYAEDSGTYMCKATNKLGEAVNTCT-LKV 2201 D+GTY C+AT+ + V+ T LKV Sbjct: 351 QVVPSDAGTYKCEATSSGSQPVSAETRLKV 380 Score = 39.5 bits (88), Expect = 0.065 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 7/100 (7%) Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499 V P F+ R + N G V F C + N V W KNG + F + D Sbjct: 380 VNYPPVFIKRLRD-HNAYTGSVVTFNCTADGNPKPN--VYWSKNGYKIG-STDFTKVGD- 434 Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539 G++ ++ DL+ D G+Y C A N +G+ + S L+ T Sbjct: 435 GFLKVE--DLLPSDMGMYQCFATNSLGSIQASAELSVYKT 472 Score = 39.5 bits (88), Expect = 0.065 Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 6/96 (6%) Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 + PVF ++D F G+PK V W +NG I S T + D G Sbjct: 380 VNYPPVFIKRLRDHNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI-GSTDFTKVGD-G 435 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 + L ++ + P D G Y C A N LG S+ L V Sbjct: 436 F--LKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 6/99 (6%) Query: 2903 VPDTEYPK-PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK 2961 +PD P+ ++++ + ++G+ LE V K P ++WY NG+++ SR Sbjct: 283 IPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAV--KGSPKPVVKWYKNGQIVTYDSRVT 340 Query: 2962 LTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 + G L+++ V D+G Y C+A + + ++ T Sbjct: 341 I---IGESNLEIMQVVPSDAGTYKCEATSSGSQPVSAET 376 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 5/74 (6%) Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714 ++G+H LE V+ P +K W+KNG +T +R+ G L I + D+G Sbjct: 305 IKGKHTVLECAVKGSPKPVVK--WYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGT 359 Query: 2715 YTCKATNLLGEAVS 2728 Y C+AT+ + VS Sbjct: 360 YKCEATSSGSQPVS 373 Score = 39.1 bits (87), Expect = 0.086 Identities = 53/196 (27%), Positives = 78/196 (39%), Gaps = 29/196 (14%) Query: 3429 IENLREGENAHFEARLT--PTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTY 3486 I+ LR+ NA+ + +T T D N K YW+ K GS T GF L++ Sbjct: 387 IKRLRD-HNAYTGSVVTFNCTADGNPKPNVYWSKNGYKIGSTDFTKVGDGF--LKVEDLL 443 Query: 3487 PEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVD 3546 P D G Y C A N+ G +A + V + ++LP + T Sbjct: 444 PSDMGMYQCFATNSLGSIQASAELSVYKTGVPLPTTRLPTTAQ--------------TPT 489 Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606 T+ P + PP TT P + + + R I +DS + V W P T +V Sbjct: 490 TILPPTTTPTPPPTTTEPQ---RPPDPPRNVQARTI--SDSEIEVTWI---PPKNTYGKV 541 Query: 3607 KTINDFGFVILEIGGV 3622 + N F L GG+ Sbjct: 542 LSYN--MFFTLSKGGI 555 Score = 38.7 bits (86), Expect = 0.11 Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 6/79 (7%) Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250 +GK+ LEC ++ G P V+W+ NG+ VT SR G L+I+ +D G Y Sbjct: 306 KGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTY 360 Query: 1251 TVRAVNHLGSAHTSAIVRV 1269 A + GS SA R+ Sbjct: 361 KCEATSS-GSQPVSAETRL 378 Score = 38.3 bits (85), Expect = 0.15 Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 5/78 (6%) Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379 + ++G + LEC ++ G V+W+ NG+ + R E + L+++ V P D Sbjct: 302 VVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTIIGESN---LEIMQVVPSD 356 Query: 1380 SGVYTCQATNQLGEAVTS 1397 +G Y C+AT+ + V++ Sbjct: 357 AGTYKCEATSSGSQPVSA 374 Score = 38.3 bits (85), Expect = 0.15 Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 12/106 (11%) Query: 51 QVESSGDRQPITAG-RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109 + SSG QP++A R PP+F + ++ G F GNP P V W++ Sbjct: 363 EATSSGS-QPVSAETRLKVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYWSK-- 419 Query: 110 APLVECNKYSMRYNEQT--GDVSLLIKQIGPGDEGEYTCTARNQYG 153 N Y + + T GD L ++ + P D G Y C A N G Sbjct: 420 ------NGYKIGSTDFTKVGDGFLKVEDLLPSDMGMYQCFATNSLG 459 Score = 37.5 bits (83), Expect = 0.26 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 7/102 (6%) Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894 + + VN P FI +L + G + C + P PN V W NG + S + Sbjct: 375 ETRLKVNYPPVFIKRLRDHNAYT-GSVVTFNCTADGNPKPN--VYWSKNGYKIGSTDFTK 431 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 + F L + + D G Y C A N+LG +S L+V Sbjct: 432 VGDGF----LKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469 Score = 36.7 bits (81), Expect = 0.46 Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 15/127 (11%) Query: 1940 ESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEA 1999 E+ + H SA + + D +RA FVV P IK H V LE Sbjct: 265 ENPVTKRTHSSAYATLTVIPDRGNPRRA----DFVVTPPSRVVAIKGK-----HTV-LEC 314 Query: 2000 TLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059 + P V+WY NG+ V R G L+I+ D GTY C+AT++ Sbjct: 315 AVK--GSPKPVVKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTYKCEATSSGS 369 Query: 2060 EAVTTSS 2066 + V+ + Sbjct: 370 QPVSAET 376 Score = 36.3 bits (80), Expect = 0.61 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 3/54 (5%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664 V+WY N + + SR T G L+IM +P D+GTY C A ++ + V++ Sbjct: 324 VKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTYKCEATSSGSQPVSA 374 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 7/97 (7%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 V P+F L+ ++ G V + PN + W KNG + + K F Sbjct: 380 VNYPPVFIKRLRDHNAYT-GSVVTFNCTADGNPKPN--VYWSKNGYKIGSTDFTKVGDGF 436 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 L + L D G+Y C ATN LG ++A + + Sbjct: 437 ----LKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469 Score = 35.9 bits (79), Expect = 0.80 Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 7/75 (9%) Query: 2513 VLTGPSELW--EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDI 2570 V+T PS + +G+H E V G P +WY NG + SR G L+I Sbjct: 295 VVTPPSRVVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTI---IGESNLEI 349 Query: 2571 NSVVANDAGLYMCKA 2585 VV +DAG Y C+A Sbjct: 350 MQVVPSDAGTYKCEA 364 Score = 35.5 bits (78), Expect = 1.1 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 7/93 (7%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 PVF+ L N G F C + +P + W NG KI G T G++ Sbjct: 384 PVFIKRLRD-HNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI--GSTDFTKVGDGFLK 438 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 ++ L D G Y C ATN LG + L V Sbjct: 439 VEDLLP--SDMGMYQCFATNSLGSIQASAELSV 469 Score = 34.7 bits (76), Expect = 1.9 Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 14/146 (9%) Query: 1169 IEEISKSK--PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG--S 1224 + EI+ S+ P F++ S+ V + + L+CR G P+ R+ W HNG + + Sbjct: 74 VNEITSSQLAPFFLEEPSDIV-VKKNRQALLKCRAG--GLPSPRISWRHNGNDLNLAGDK 130 Query: 1225 RFKTYYDFGFVALDIIHATSA--DTGEYTVRA---VNHLGSAHTSAIVRVIERSDIVTDT 1279 R K D + + I H S+ D G Y A VN+L S IV+ ++ + + + Sbjct: 131 RRKILPDGSLLFITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVK-LQVAGLSSKI 189 Query: 1280 QNEQAIEQIQLLEDAARRTKQVREDI 1305 E Q+ + D AR +VR + Sbjct: 190 TIEPVTSQV-IFGDVARLFCKVRHSL 214 Score = 34.7 bits (76), Expect = 1.9 Identities = 17/46 (36%), Positives = 19/46 (41%) Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 K PPVF+ G F C G+PKP V W NG I Sbjct: 379 KVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYWSKNGYKI 424 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 2/91 (2%) Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147 + +S T + + R V+ P V +G+ C V G PKP V W N Sbjct: 270 KRTHSSAYATLTVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAVKGSPKPVVKWYKN 329 Query: 4148 GNTIVNGSRYKLTYDGMYHFDIPKTRQYDTG 4178 G + SR +T G + +I + D G Sbjct: 330 GQIVTYDSR--VTIIGESNLEIMQVVPSDAG 358 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%) Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840 + +V +G + EC V+ S P +K W+ N + + +R + + L+I Sbjct: 300 SRVVAIKGKHTVLECAVKGSPKPVVK--WYKNGQIVTYDSRVTIIGESN---LEIMQVVP 354 Query: 2841 EDSGIYTCKATNSKGSATTSGSLR 2864 D+G Y C+AT+S GS S R Sbjct: 355 SDAGTYKCEATSS-GSQPVSAETR 377 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G + E ++G+P PVV W K +V Y R G+ +L I Q+ P D G Y Sbjct: 306 KGKHTVLECAVKGSPKPVVKWY-KNGQIVT---YDSRVTI-IGESNLEIMQVVPSDAGTY 360 Query: 145 TCTARNQYGEAI 156 C A + + + Sbjct: 361 KCEATSSGSQPV 372 Score = 34.3 bits (75), Expect = 2.5 Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 6/98 (6%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 + V P F + L + G+ V C G+ V W NG I + + Sbjct: 378 LKVNYPPVFIKRLRDHNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKIGSTDFTKVGDG 435 Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 F V DLL P D G+Y C ATN LG S L V Sbjct: 436 FLKVE-DLL---PSDMGMYQCFATNSLGSIQASAELSV 469 Score = 34.3 bits (75), Expect = 2.5 Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%) Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300 PP F+ LR + + G F C + PN + + NG + S + F Sbjct: 383 PPVFIKRLRDH-NAYTGSVVTFNCTADGNPKPN--VYWSKNGYKIGSTDFTKVGDGF--- 436 Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360 L ++ +P D G Y A N+LG ++ ++V G + ++ P + + Sbjct: 437 -LKVEDLLPSDMGMYQCFATNSLGSIQASAELSVYKTGVPLPTTRLPTTAQTPTTI--LP 493 Query: 2361 PFKRPEIPEPVTR-QRP 2376 P P P T QRP Sbjct: 494 PTTTPTPPPTTTEPQRP 510 Score = 34.3 bits (75), Expect = 2.5 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 9/100 (9%) Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031 PP F+ +++ + T F C G+P V W NG + FT + D G++ Sbjct: 383 PPVFIKRLRDHNAYTGSVVT-FNCTAD--GNPKPNVYWSKNGYKI-GSTDFTKVGD-GFL 437 Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKT--TGKP 4069 + + P D G Y C ATN G + A + TG P Sbjct: 438 KVED--LLPSDMGMYQCFATNSLGSIQASAELSVYKTGVP 475 Score = 34.3 bits (75), Expect = 2.5 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 7/83 (8%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 PVF + L++ N G F+C G+P V W +N I S+ TK D G++ Sbjct: 384 PVFIKRLRD-HNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI-GSTDFTKVGD-GFLK 438 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 + + D G+Y C A+N LG Sbjct: 439 --VEDLLPSDMGMYQCFATNSLG 459 Score = 33.9 bits (74), Expect = 3.2 Identities = 56/201 (27%), Positives = 79/201 (39%), Gaps = 14/201 (6%) Query: 3498 YNNYGEAVTTAS-MKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGN 3556 Y N G+ VT S + + G+ N+ + +P GT K A S V T + Sbjct: 327 YKN-GQIVTYDSRVTIIGESNLEIMQVVPSDA-GTY-KCEATSSGSQPVSAET-RLKVNY 382 Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 PP F D S F C + V W NG + GS T GF Sbjct: 383 PPVFIKRLRDHNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI--GSTDFTKVGDGF-- 436 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL-EPQLPSHFKSGTESIQKL 3675 L++ + D G+Y C ATN G S +L V + G+ L +LP+ ++ T +I Sbjct: 437 LKVEDLLPSDMGMYQCFATNSLGSIQASAELSVY-KTGVPLPTTRLPTTAQTPT-TILPP 494 Query: 3676 EETLHKREEITIEDEKPNPPR 3696 T T P+PPR Sbjct: 495 TTTPTPPPTTTEPQRPPDPPR 515 Score = 33.5 bits (73), Expect = 4.3 Identities = 18/81 (22%), Positives = 39/81 (48%), Gaps = 4/81 (4%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ--RLINSNKHEIITTHNHTTL 323 P ++P + +++ A + + G P PR++W NG L + +I+ + + Sbjct: 84 PFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKILPDGSLLFI 143 Query: 324 RVRNTQ--KSDSGHYTLLAEN 342 + +T+ K D G+Y +A + Sbjct: 144 TIEHTKSSKPDEGNYQCVASS 164 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEY 2315 +GK EC V+ P +++Y NG+ + +R I G +L+I VP DAG Y Sbjct: 306 KGKHTVLECAVKG--SPKPVVKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTY 360 Query: 2316 SVKAINALGHCTSA 2329 +A ++ SA Sbjct: 361 KCEATSSGSQPVSA 374 Score = 33.5 bits (73), Expect = 4.3 Identities = 26/89 (29%), Positives = 34/89 (38%), Gaps = 6/89 (6%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 VFI L + G + F C + + P + W N + S K F L Sbjct: 385 VFIKRLRDHNAYTGSVVTFNCTADGNPKPN--VYWSKNGYKIGSTDFTKVGDGF----LK 438 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 + D G+Y C ATNS GS S L Sbjct: 439 VEDLLPSDMGMYQCFATNSLGSIQASAEL 467 Score = 33.1 bits (72), Expect = 5.7 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455 G P V+W++N +++ SR+T G ++ I V D G Y C A++ Sbjct: 318 GSPKPVVKWYKNGQIVTYDSRVT---IIGESNLEIMQVVPSDAGTYKCEATS 366 Score = 32.7 bits (71), Expect = 7.5 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 7/93 (7%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 PVF++ L + + G + C + G+P V W NG + GS T GF+ Sbjct: 384 PVFIKRLRDHNAYT-GSVVTFNCTAD--GNPKPNVYWSKNGYKI--GSTDFTKVGDGFLK 438 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269 ++ + +D G Y A N LGS SA + V Sbjct: 439 VEDL--LPSDMGMYQCFATNSLGSIQASAELSV 469 >SB_37927| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1032 Score = 95.9 bits (228), Expect = 7e-19 Identities = 86/318 (27%), Positives = 130/318 (40%), Gaps = 27/318 (8%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW-FKN--GQRLINSNKHEIITTHNHT 321 PP ++ +P N+ G Q G+P P VTW FKN + + S + II N Sbjct: 513 PPTVSGRPTNATRIVGESHTVTCQFQGSPAPLVTWFFKNDTADQTVPSTLNYII---NGG 569 Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381 L ++ KSD G + NP G S L V+ + + + Q R++ + Sbjct: 570 ILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLRPLQTRDS-K 622 Query: 382 RIEISEKALAPQFVKVCQ-DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440 +++ A P F+ + V E F+C+ +G P P VTW+ + + I Sbjct: 623 LVKLDVSASVPVFLDAGPVNVTVNETSTASFECQASGDPTPTVTWYRGQTALTHGGRYVI 682 Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500 G L I SD+G C N L ++ + RF+ L Sbjct: 683 -----GQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHL-FVQVPAAITSFTAPRFAQL 736 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 N G ++ G P+PRITW +D + P+ R+ +GG +L I R SD Sbjct: 737 N---GSTTLI-CLTRGIPSPRITWYRDRRVVTPDGS-RVTINGG--SLSIARVTRSDGGT 789 Query: 561 YQCTAQNVAGSTATRARL 578 Y C A N AG T+ A L Sbjct: 790 YACAASNAAGMTSRTANL 807 Score = 91.9 bits (218), Expect = 1e-17 Identities = 104/416 (25%), Positives = 157/416 (37%), Gaps = 45/416 (10%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F+ K Q V EH+ G P+P + W ++N + D T + L I Sbjct: 425 PTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQAV----DTNHVTLHSNGSLSI 480 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 +V D ++ VA N G+A A L V+ VPP+ + N G+ Sbjct: 481 TRVLFSDRGSYSCVATNVAGSASSVATLTVQ----------VPPTVSGRPTNATRIVGES 530 Query: 4531 VRLDTKVTGTK-PIDVYWLKNGKKVQ--PDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 + + G+ P+ ++ KN Q P N I+ L I D G + C Sbjct: 531 HTVTCQFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGG---ILTIKAVTKSDEGTFVCK 587 Query: 4588 AINSAGEARCDAECVVSLPAT--KDKPKPQTK---------AANAPPEIIEPLKDKIVAE 4636 N AG A A V + +D QT+ +A+ P + + V E Sbjct: 588 GTNPAGAAEASANLYVKGESMTPRDLRPLQTRDSKLVKLDVSASVPVFLDAGPVNVTVNE 647 Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 F C+ G P PTV WY+G + + + + TL I + P D G+Y+C Sbjct: 648 TSTASFECQASGDPTPTVTWYRGQTALTHGGRYVIG----QGTLTILRSNPSDTGEYRCN 703 Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI-KPTIQWL 4755 N A L V P A+T + + +T I P I W Sbjct: 704 VTNGLATHVGVAHLFVQVP------AAITSFTAPRFAQLNGSTTLICLTRGIPSPRITWY 757 Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 R+ ++ TPD + N L I D GT+ C A+ AAG +A L ++ Sbjct: 758 RDRRVV--TPDGSRV-TINGGSLSIARVTRSDGGTYACAASNAAGMTSRTANLTIQ 810 Score = 85.0 bits (201), Expect = 1e-15 Identities = 80/293 (27%), Positives = 114/293 (38%), Gaps = 27/293 (9%) Query: 4524 NVTSGQLVRLDTKVTGTKPIDVY--WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581 NVT G V L+ + PI V W +N + VQ + + TL A D Sbjct: 340 NVTEGAPVSLECDPPNSYPIGVAITWFRNYQVVQ---LGSGITVSSSGTLTFATAKKADE 396 Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641 G+Y C +NS A + ++L +P TK N V E Q++ Sbjct: 397 GEYFCSVVNSYLHASRSSS--IALLTVWVRPTFSTKPQNTT-----------VIEHQSLL 443 Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701 C G P+P+V W K ++ + + S + L I+ D G Y CVA N A Sbjct: 444 LICAATGYPMPSVLWLKDNQAVDTNHVTLHSNGS----LSITRVLFSDRGSYSCVATNVA 499 Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761 G + A L V P P T IV G+ Q P + W + Sbjct: 500 GSASSVATLTVQVPPTVSGRP--TNATRIV---GESHTVTCQFQGSPAPLVTWFFKNDTA 554 Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 +T + + N +L I + D GTF C+ T AG E SA L VK ++ Sbjct: 555 DQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKGES 607 Score = 66.9 bits (156), Expect = 4e-10 Identities = 76/307 (24%), Positives = 115/307 (37%), Gaps = 46/307 (14%) Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571 V P+F+ QN V Q + L TG V WLK+ + V D + L +G +L Sbjct: 423 VRPTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQAV--DTNHVTLHSNG--SL 478 Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631 I D G Y CVA N AG A A V +P P + NA Sbjct: 479 SITRVLFSDRGSYSCVATNVAGSASSVATLTVQVP-----PTVSGRPTNA---------T 524 Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691 +IV E + +C+ G P P V W+ + + ++ + L I DEG Sbjct: 525 RIVGESHTV--TCQFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEG 582 Query: 4692 DYKCVAYNSAGRVTVAAKL--------------------KVTQPDQADNLPALTPLR--D 4729 + C N AG +A L K+ + D + ++P + Sbjct: 583 TFVCKGTNPAGAAEASANLYVKGESMTPRDLRPLQTRDSKLVKLDVSASVPVFLDAGPVN 642 Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789 + V E A F+ Q + PT+ W R + + +I +G +L + DTG Sbjct: 643 VTVNETSTASFECQASGDPTPTVTWYRGQTALTHGGRY-VIGQGTLTIL---RSNPSDTG 698 Query: 4790 TFTCRAT 4796 + C T Sbjct: 699 EYRCNVT 705 Score = 66.5 bits (155), Expect = 5e-10 Identities = 78/326 (23%), Positives = 115/326 (35%), Gaps = 45/326 (13%) Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492 +F G P PL+ W+ +N + ++ IL I+ V D F N G A Sbjct: 536 QFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAA 595 Query: 4493 KCSANLVVEEKRRQGR-----------------GGIVPPSFTLTAQNVNVTSGQLVRLDT 4535 + SANL V+ + R VP NV V + Sbjct: 596 EASANLYVKGESMTPRDLRPLQTRDSKLVKLDVSASVPVFLDAGPVNVTVNETSTASFEC 655 Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595 + +G V W + + R I G TL IL + P D+G+Y C N Sbjct: 656 QASGDPTPTVTWYRGQTALTHGGRYVI----GQGTLTILRSNPSDTGEYRCNVTNGLATH 711 Query: 4596 RCDAECVVSLPATKDK-PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654 A V +PA P+ N +I C G P P + Sbjct: 712 VGVAHLFVQVPAAITSFTAPRFAQLNGSTTLI-----------------CLTRGIPSPRI 754 Query: 4655 QWYKGDKLIKPSKYFQMSR-TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV- 4712 WY+ +++ P SR T + +L I+ D G Y C A N+AG + A L + Sbjct: 755 TWYRDRRVVTPDG----SRVTINGGSLSIARVTRSDGGTYACAASNAAGMTSRTANLTIQ 810 Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPA 4738 PD ++ AL + +PA Sbjct: 811 VPPDPPTDVSALPLTSTSIKLSWKPA 836 Score = 65.3 bits (152), Expect = 1e-09 Identities = 56/190 (29%), Positives = 75/190 (39%), Gaps = 14/190 (7%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P F Q+ V E + C TG P P V W +++ + D NH L N +L Sbjct: 425 PTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQAV--DTNHVTL---HSNGSLS 479 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511 IT V SD G +CVA N +G + L V V P R + GE + Sbjct: 480 ITRVLFSDRGSYSCVATNVAGSASSVATLTV-----QVPPTVSGRPTNATRIVGESHTVT 534 Query: 512 ARAVGTPTPRITW--QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 + G+P P +TW + D L +GG L I SD + C N A Sbjct: 535 CQFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGG--ILTIKAVTKSDEGTFVCKGTNPA 592 Query: 570 GSTATRARLY 579 G+ A LY Sbjct: 593 GAAEASANLY 602 Score = 59.3 bits (137), Expect = 8e-08 Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 16/195 (8%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066 P V W+ Q Y L I D GT++CK TN G A +++ Sbjct: 541 PAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEASAN 600 Query: 2067 VKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDR 2126 + V +S + + L+ +Q + K ++ + PVFL A + E Sbjct: 601 LYVKGES------MTPRDLRPLQTRDS----KLVKLDVSASVPVFLDAGPVNVTVNETST 650 Query: 2127 AHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186 A FEC+ DP T+ W+ + G RY G L IL + D+G Y C Sbjct: 651 ASFECQAS--GDPTPTVTWYRGQTALTHGGRY----VIGQGTLTILRSNPSDTGEYRCNV 704 Query: 2187 TNKLGEAVNTCTLKV 2201 TN L V L V Sbjct: 705 TNGLATHVGVAHLFV 719 Score = 58.8 bits (136), Expect = 1e-07 Identities = 53/188 (28%), Positives = 79/188 (42%), Gaps = 14/188 (7%) Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYP---EVTWFINDRQIRDDYNHKILVNESGNHAL 450 F K ++VTEG +C YP +TWF N + ++ I V+ SG L Sbjct: 332 FHKHPSSQNVTEGAPVSLECDPPNS-YPIGVAITWFRNYQVVQ--LGSGITVSSSGT--L 386 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 +D G C N + + ++ V P F + V E + ++L Sbjct: 387 TFATAKKADEGEYFCSVVNSYLHASRSSSIALLTVW--VRPTFSTKPQNTTVIEHQSLLL 444 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 A G P P + W KD + N + +H++G +L I R SD Y C A NVAG Sbjct: 445 ICAATGYPMPSVLWLKDNQAVDTN-HVTLHSNG---SLSITRVLFSDRGSYSCVATNVAG 500 Query: 571 STATRARL 578 S ++ A L Sbjct: 501 SASSVATL 508 Score = 58.4 bits (135), Expect = 1e-07 Identities = 58/205 (28%), Positives = 79/205 (38%), Gaps = 18/205 (8%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P V W + + T + L +K V D GT+ C+ N G A S Sbjct: 539 GSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEAS 598 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857 + L+V+ ES L+ + Q DS + DV +V P F+ ++ Sbjct: 599 ANLYVKG------ESMTPRDLRPL-QTRDSKLV--KLDVSASV---PVFLDAGPVNVTVN 646 Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 E +A +EC+ DP V WY L G RY G L IL D+GEY Sbjct: 647 ETSTASFECQAS--GDPTPTVTWYRGQTALTHGGRY----VIGQGTLTILRSNPSDTGEY 700 Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942 C N L V L VQ +I Sbjct: 701 RCNVTNGLATHVGVAHLFVQVPAAI 725 Score = 58.4 bits (135), Expect = 1e-07 Identities = 62/245 (25%), Positives = 97/245 (39%), Gaps = 41/245 (16%) Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297 ES+T R + + S + + P + P N + E + A F+ Q SG+P P V Sbjct: 606 ESMTPRDLRPLQTRDSKLVKLDVSASVPVFLDAGPVNVTVNETSTASFECQASGDPTPTV 665 Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 TW++ L + ++ I TL + + SD+G Y C VT+G Sbjct: 666 TWYRGQTALTHGGRYVI----GQGTLTILRSNPSDTGEYR--------CNVTNGLATHVG 713 Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417 +VQ + IT AP+F ++ G T C G Sbjct: 714 VAHLFVQVPAA--ITSFT---------------APRFAQL-------NGSTTLI-CLTRG 748 Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477 P P +TW+ DR++ ++ +N +L I VT SD G C A N +G T+ Sbjct: 749 IPSPRITWY-RDRRVVTPDGSRVTINGG---SLSIARVTRSDGGTYACAASNAAGMTSRT 804 Query: 478 CRLNV 482 L + Sbjct: 805 ANLTI 809 Score = 58.0 bits (134), Expect = 2e-07 Identities = 79/311 (25%), Positives = 117/311 (37%), Gaps = 33/311 (10%) Query: 3065 IAHYEASLI--PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYS 3122 I H LI TG + W + + ++ +H T+++ G L I +D G+YS Sbjct: 437 IEHQSLLLICAATGYPMPSVLWLKDNQAVDTNHV--TLHSNGS--LSITRVLFSDRGSYS 492 Query: 3123 CRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181 C ATN G A L V + +P T+ I G + F+ + P+ Sbjct: 493 CVATNVAGSASSVATLTVQVPPTVSGRP---TNATRIVGESHTVTCQFQGSPAPL----- 544 Query: 3182 KIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINC 3241 + W+ + +L I D G +VC+ N G A+ N Sbjct: 545 -VTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGA--AEASANL 601 Query: 3242 YGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAH 3301 Y KG ES+ P L ++ +S + SA P F+ + E +A Sbjct: 602 YVKG----ESMTPRDLRPLQTRDS-----KLVKLDVSASVPVFLDAGPVNVTVNETSTAS 652 Query: 3302 FEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATN 3361 FE + DP V W+ L HG RY G L IL ++GEY C TN Sbjct: 653 FECQ--ASGDPTPTVTWYRGQTALTHGGRY----VIGQGTLTILRSNPSDTGEYRCNVTN 706 Query: 3362 KLGRDSTKANL 3372 L A+L Sbjct: 707 GLATHVGVAHL 717 Score = 56.8 bits (131), Expect = 4e-07 Identities = 53/164 (32%), Positives = 74/164 (45%), Gaps = 22/164 (13%) Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162 L I +V D G + N AG A+ SA++ V+ S T R L +TR +SK Sbjct: 571 LTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKGESM--TPRDLRPL--QTR---DSKL 623 Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222 V+ ++S S PVF+ V+E EC+ GDPT V W+ ++T Sbjct: 624 VKL-----DVSASVPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTH 676 Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN----HLGSAH 1262 G R Y G L I+ + +DTGEY N H+G AH Sbjct: 677 GGR----YVIGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAH 716 Score = 53.6 bits (123), Expect = 4e-06 Identities = 49/179 (27%), Positives = 80/179 (44%), Gaps = 22/179 (12%) Query: 409 TRFDCRVTG--RPYPEVTWFINDRQIRDDYNHKILV---NESGNHA-LMITNVTLSDSGV 462 T F C VTG +P+ V W + ++ + +L+ N S A + + N+TL +G Sbjct: 149 THFAC-VTGISKPFASVYWEKDGVKLTEYPTTSMLIPTDNPSWTSASISVRNITLKSAGF 207 Query: 463 VTCVARN-------KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515 CVA N K + A+ L I+ AP F S+ + E + L + Sbjct: 208 YRCVAVNPMLPNLPKKSQPAYLQVLPAID-----APHFQVHPSSTTIAELQSAALQCHIL 262 Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574 G PTP +TW+ + ++ +P+ R G +L A + A Y+CT N GS ++ Sbjct: 263 GVPTPSVTWEFNSNGLLDSPD-RYQLSNG--SLYFKSANRTMAGVYKCTGTNSVGSVSS 318 Score = 52.8 bits (121), Expect = 7e-06 Identities = 52/210 (24%), Positives = 80/210 (38%), Gaps = 22/210 (10%) Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030 Q P V+ + + + E+ CQ G P V WFF T Y Sbjct: 511 QVPPTVSGRPTNATRIVGESHTVTCQFQ--GSPAPLVTWFFKNDTADQTVPSTLNYIING 568 Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREM 4090 + V D G ++C+ TN G E A + G +S P+ ++ + Sbjct: 569 GILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLRPL------ 616 Query: 4091 EASWQVTPEQVVEESKARCPPVFVSL-PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149 Q ++V+ + PVF+ P VTV E A F C+ +G P P V W Sbjct: 617 ----QTRDSKLVKLDVSASVPVFLDAGPVNVTVNETSTASFECQASGDPTPTVTWYRGQT 672 Query: 4150 TIVNGSRYKLTYDGMYHFDIPKTRQYDTGK 4179 + +G RY + G I ++ DTG+ Sbjct: 673 ALTHGGRYVI---GQGTLTILRSNPSDTGE 699 Score = 50.4 bits (115), Expect = 3e-05 Identities = 57/217 (26%), Positives = 78/217 (35%), Gaps = 19/217 (8%) Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918 G+S C+ + P P V W+F + L I V D G + Sbjct: 528 GESHTVTCQFQGSPAP--LVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFV 585 Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKP 1978 CK N G A +S L V+ + RD L +Q DS+ + D S V Sbjct: 586 CKGTNPAGAAEASANLYVKGESMTPRD------LRPLQ--TRDSKLVKL--DVSASVPVF 635 Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038 P+ N V E E + DPT V WY + G R Y G L Sbjct: 636 LDAGPV-NVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTHGGR----YVIGQGTLT 688 Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGL 2075 IL + DTG Y C TN + V + + V + + Sbjct: 689 ILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQVPAAI 725 Score = 50.0 bits (114), Expect = 5e-05 Identities = 72/298 (24%), Positives = 109/298 (36%), Gaps = 40/298 (13%) Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997 + P + W+F +Q L L + V + D G + CK N G A Sbjct: 538 QGSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEA 597 Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI 3057 S+ +Y +++ R P +Q + L K D + P F Sbjct: 598 SANLYVKG-ESMTPRDLRP--------LQTRDSKLVKL------DVSASVPVFLDAGPVN 642 Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117 V ++E A +E +GD + + W Y G+T +H R Y G L IL + +D Sbjct: 643 VTVNETSTASFECQA--SGDPTPTVTW-YRGQTA-LTHGGR--YVIGQGTLTILRSNPSD 696 Query: 3118 SGTYSCRATN----KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173 +G Y C TN G A + V++ S PRF + G S C Sbjct: 697 TGEYRCNVTNGLATHVGVAHLFVQVPAAITS-FTAPRFA----QLNG-----STTLICLT 746 Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 + P +I WY + + + T++ L IA D G Y C A N G Sbjct: 747 RGIPSP--RITWYRDRRVVTPDGSRVTINGGS---LSIARVTRSDGGTYACAASNAAG 799 Score = 50.0 bits (114), Expect = 5e-05 Identities = 46/165 (27%), Positives = 63/165 (38%), Gaps = 17/165 (10%) Query: 2178 DSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEP 2237 D GT++CK TN G A + L V G ++ P L + Q +++ + Sbjct: 580 DEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLRPL-----QTRDSKLVKLDV 628 Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297 S P F+ V E TA FECQ DP + +Y AL R+ I Sbjct: 629 SASVPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTHGGRYVI---- 682 Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIIS 2342 G +L I P D GEY N L + V +I S Sbjct: 683 GQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQVPAAITS 727 Score = 49.6 bits (113), Expect = 6e-05 Identities = 51/189 (26%), Positives = 76/189 (40%), Gaps = 23/189 (12%) Query: 2676 IEWF-KNGVT-LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733 + WF KN T + L + G++T I ++ D G + CK TN G A ++A++ Sbjct: 545 VTWFFKNDTADQTVPSTLNYIINGGILT--IKAVTKSDEGTFVCKGTNPAGAAEASANLY 602 Query: 2734 IEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFI-SHLNNIVCKEGDNIH 2792 ++ GES+ P L + VF+ + N+ E Sbjct: 603 VK------GESMTPRDLRPL----QTRDSKLVKLDVSASVPVFLDAGPVNVTVNETSTAS 652 Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852 FEC + S DPT + W+ L G RY +L I + D+G Y C TN Sbjct: 653 FEC--QASGDPTPTVTWYRGQTALTHGGRYV----IGQGTLTILRSNPSDTGEYRCNVTN 706 Query: 2853 SKGSATTSG 2861 G AT G Sbjct: 707 --GLATHVG 713 Score = 48.4 bits (110), Expect = 1e-04 Identities = 47/173 (27%), Positives = 66/173 (38%), Gaps = 19/173 (10%) Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696 L I + D GT+ C+ N G A S ++Y++ E PR L Sbjct: 571 LTIKAVTKSDEGTFVCKGTNPAGAAEASA--------NLYVKG--ESMTPR--DLRPLQT 618 Query: 1697 YQRHSAQDEVITQAPVF-TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755 + +V PVF ++ V E A FE + GDP V W R + Sbjct: 619 RDSKLVKLDVSASVPVFLDAGPVNVTVNETSTASFECQ--ASGDPTPTVTWYRGQTALTH 676 Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 R + G L + NP D+G Y C N L V + LFVQ A++ Sbjct: 677 GGR----YVIGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQVPAAI 725 Score = 48.0 bits (109), Expect = 2e-04 Identities = 55/188 (29%), Positives = 74/188 (39%), Gaps = 22/188 (11%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDF--GFIALDIDYIYARDAGEYTCRATNKWGSAT 3780 G P + WF A + TLN G I L I + D G + C+ TN G+A Sbjct: 539 GSPAPLVTWFFKNDT-ADQTVPSTLNYIINGGI-LTIKAVTKSDEGTFVCKGTNPAGAAE 596 Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHT 3840 +A + ES P+ ++ L+ R S K + S P + T Sbjct: 597 ASANLYVKG------ESMTPR-----DLRPLQT-RDSKLVKLDVSASVPVFLDAGPVNVT 644 Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900 V E+ FEC + DP + WYR L G RY V G +L IL D+G Sbjct: 645 VNETSTASFEC--QASGDPTPTVTWYRGQTALTHGGRY--VIGQG--TLTILRSNPSDTG 698 Query: 3901 EYICRAVN 3908 EY C N Sbjct: 699 EYRCNVTN 706 Score = 48.0 bits (109), Expect = 2e-04 Identities = 54/182 (29%), Positives = 75/182 (41%), Gaps = 22/182 (12%) Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028 LTIK+VT D G + C+ N G A SANL + ES P L +Q +R Sbjct: 571 LTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVK------GESMTPRDLRPLQ-----TR 619 Query: 1029 YSKRTEEEVKITQKPRFL--GPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086 SK + +V P FL GP+ T + E +A FE + D T TV WY + Sbjct: 620 DSKLVKLDVS-ASVPVFLDAGPVNVT--VNETSTASFEC--QASGDPTPTVTWYRGQTAL 674 Query: 1087 TSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSI 1146 T R + G L I D+G Y N A + V+ ++I + + Sbjct: 675 THGGR----YVIGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQVPAAITSFTA 730 Query: 1147 HR 1148 R Sbjct: 731 PR 732 Score = 47.2 bits (107), Expect = 3e-04 Identities = 47/159 (29%), Positives = 58/159 (36%), Gaps = 22/159 (13%) Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675 IL I V + D G + CK TN G A S L VKG E P + +Q Sbjct: 570 ILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLR----PLQTR 619 Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735 + L K D + P F N+ V E F+C+ GDPT + W+ Sbjct: 620 DSKLVKL------DVSASVPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQ 671 Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774 G R G L I D GEY C TN Sbjct: 672 TALTHGGRY----VIGQGTLTILRSNPSDTGEYRCNVTN 706 Score = 46.8 bits (106), Expect = 4e-04 Identities = 50/178 (28%), Positives = 77/178 (43%), Gaps = 23/178 (12%) Query: 4537 VTG-TKPI-DVYWLKNGKKVQ--PDIRNKILEEDGTYT---LLILEAYPQDSGKYECVAI 4589 VTG +KP VYW K+G K+ P I ++ ++T + + + +G Y CVA+ Sbjct: 154 VTGISKPFASVYWEKDGVKLTEYPTTSMLIPTDNPSWTSASISVRNITLKSAGFYRCVAV 213 Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQT-KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648 N + +LP Q A +AP + P +AE Q+ C I+G Sbjct: 214 NPM---------LPNLPKKSQPAYLQVLPAIDAPHFQVHP-SSTTIAELQSAALQCHILG 263 Query: 4649 KPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705 P P+V W + + L+ +Q+S +L A G YKC NS G V+ Sbjct: 264 VPTPSVTWEFNSNGLLDSPDRYQLSNG----SLYFKSANRTMAGVYKCTGTNSVGSVS 317 Score = 46.8 bits (106), Expect = 4e-04 Identities = 51/206 (24%), Positives = 77/206 (37%), Gaps = 23/206 (11%) Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSV--TVGSRFKTYYDFGFVALDIIHATSADTGE 1249 G++ + C+ + G P V WF + TV S + G + + + T +D G Sbjct: 528 GESHTVTCQFQ--GSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAV--TKSDEGT 583 Query: 1250 YTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309 + + N G+A SA + V S D + Q R +K V+ D++ Sbjct: 584 FVCKGTNPAGAAEASANLYVKGESMTPRDLRPLQT-----------RDSKLVKLDVSASV 632 Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 N+ E + EC Q GD T V W+ + G R Y Sbjct: 633 PVFLDAGPVNVTVNETSTASFEC--QASGDPTPTVTWYRGQTALTHGGR----YVIGQGT 686 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAV 1395 L +L P D+G Y C TN L V Sbjct: 687 LTILRSNPSDTGEYRCNVTNGLATHV 712 Score = 46.0 bits (104), Expect = 8e-04 Identities = 39/168 (23%), Positives = 64/168 (38%), Gaps = 18/168 (10%) Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627 L I +V +D G ++CK N AG + + +RP +L + ++ Sbjct: 571 LTIKAVTKSDEGTFVCKGTNPAG-AAEASANLYVKGESMTPRDLRPLQTRDSKLVKLDVS 629 Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687 +F+D G + T S++ G DP + W++ LT Sbjct: 630 ASVPVFLDAGPVNVTVNETSTASFECQASG-------------DPTPTVTWYRGQTALTH 676 Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 G R + G TL+I D+G Y C TN L V A + ++ Sbjct: 677 GGR----YVIGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQ 720 Score = 45.2 bits (102), Expect = 0.001 Identities = 56/223 (25%), Positives = 80/223 (35%), Gaps = 20/223 (8%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 +TV P S N + G + + C+ Q G V WF Y Sbjct: 508 LTVQVPPTVSGRPTNATRIVGESHTVTCQFQ--GSPAPLVTWFFKNDTADQTVPSTLNYI 565 Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYL 1424 + L + +V D G + C+ TN G A S L V ES P L +Q Sbjct: 566 INGGILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLRPLQ-- 617 Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484 +R K +D S ++ P F+ V E FEC+ D V W++ Sbjct: 618 ---TRDSKLVKLDVSASV-PVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQ 671 Query: 1485 QPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527 +T G R+ G L I+ D+G Y C N + T Sbjct: 672 TALTHGGRY----VIGQGTLTILRSNPSDTGEYRCNVTNGLAT 710 Score = 44.8 bits (101), Expect = 0.002 Identities = 46/207 (22%), Positives = 78/207 (37%), Gaps = 18/207 (8%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G P + W + + + T + L + ++ D G + C+ + G AE Sbjct: 539 GSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEAS 598 Query: 724 AVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQ 783 A L+V + S P L+ +Q + SK + ++ P F+ + Sbjct: 599 ANLYV------KGESMTPRDLRPLQTRD--SKLVKLDV----SASVPVFLDAGPVNVTVN 646 Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843 E A FE Q + DPT V WY+ +T R + G +L I+ D G Y Sbjct: 647 ETSTASFECQAS--GDPTPTVTWYRGQTALTHGGR----YVIGQGTLTILRSNPSDTGEY 700 Query: 844 TVRAVNKLGEAISTASIRVAARSTVTA 870 N L + A + V + +T+ Sbjct: 701 RCNVTNGLATHVGVAHLFVQVPAAITS 727 Score = 44.4 bits (100), Expect = 0.002 Identities = 54/226 (23%), Positives = 83/226 (36%), Gaps = 24/226 (10%) Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP-VTIGHRFRPIH 1497 +V + P RP + ++ H C+ + + + L +FKN T+ I Sbjct: 509 TVQVPPTVSGRPTNATRIVGESHT-VTCQFQG-SPAPLVTWFFKNDTADQTVPSTLNYII 566 Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557 + G + + + D G + C+ N G E S L + + R L +Q Sbjct: 567 NGGILTIKAVT--KSDEGTFVCKGTNPAGAAEASANLYVKGESMTPRD------LRPLQT 618 Query: 1558 LEDRSKYHRTDMVDEVTTQAPI-CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616 + SK + D V+ P+ NV + E A FE + D T V WY Sbjct: 619 RD--SKLVKLD----VSASVPVFLDAGPVNVTVNETSTASFECQ--ASGDPTPTVTWYRG 670 Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAV 1662 L G R+ G L I+ P D+G Y C N L V Sbjct: 671 QTALTHGGRYV----IGQGTLTILRSNPSDTGEYRCNVTNGLATHV 712 Score = 44.4 bits (100), Expect = 0.002 Identities = 51/173 (29%), Positives = 65/173 (37%), Gaps = 22/173 (12%) Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400 IL I + + G + C TN G ANL +S PR L LQT Sbjct: 570 ILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRD----LRPLQT- 618 Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460 DS + + D S PVF + E A FE + + DP V WY Sbjct: 619 RDSKLVKLDVSAS-----VPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQ 671 Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 +L G R+ G L I + P D+GEY C N V A + VQ Sbjct: 672 TALTHGGRYV----IGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQ 720 Score = 43.6 bits (98), Expect = 0.004 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P + KP+N+ + E +G P P V W K+ Q +++N +T H++ +L + Sbjct: 425 PTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQ-AVDTNH---VTLHSNGSLSI 480 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 SD G Y+ +A N G + L V+ P Sbjct: 481 TRVLFSDRGSYSCVATNVAGSASSVATLTVQVP 513 Score = 43.6 bits (98), Expect = 0.004 Identities = 28/66 (42%), Positives = 35/66 (53%), Gaps = 5/66 (7%) Query: 942 RVEWLKDGRPVEAS-SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000 R+ W +D R V SR+T N G +L+I VT D G Y C A NA G + +ANLT Sbjct: 753 RITWYRDRRVVTPDGSRVT--INGG--SLSIARVTRSDGGTYACAASNAAGMTSRTANLT 808 Query: 1001 IVTKKD 1006 I D Sbjct: 809 IQVPPD 814 Score = 42.3 bits (95), Expect = 0.009 Identities = 46/182 (25%), Positives = 68/182 (37%), Gaps = 18/182 (9%) Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 AP F + E + C + G P P VTW N + D + L N S L Sbjct: 237 APHFQVHPSSTTIAELQSAALQCHILGVPTPSVTWEFNSNGLLDSPDRYQLSNGS----L 292 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 + + +GV C N G + + V F + S+ NV EG PV L Sbjct: 293 YFKSANRTMAGVYKCTGTNSVGSVSSSPVFVGVAYFDFV---FHKHPSSQNVTEGAPVSL 349 Query: 511 -----NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 N+ +G ITW ++ + + + + G TL AK +D Y C+ Sbjct: 350 ECDPPNSYPIGV---AITWFRNYQVVQLGSGITVSSSG---TLTFATAKKADEGEYFCSV 403 Query: 566 QN 567 N Sbjct: 404 VN 405 Score = 42.3 bits (95), Expect = 0.009 Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 18/154 (11%) Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361 L I+ D G + K N G ++ ++ V KG ES P L ++ +S Sbjct: 571 LTIKAVTKSDEGTFVCKGTNPAGAAEASANLYV--KG----ESMTPRDLRPLQTRDSKL- 623 Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421 + V+ PVF + E TA F+C+ GDPT V W+R + + Sbjct: 624 -----VKLDVSASVPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTH 676 Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455 R + G ++TI D G Y C +N Sbjct: 677 GGR----YVIGQGTLTILRSNPSDTGEYRCNVTN 706 Score = 42.3 bits (95), Expect = 0.009 Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 6/71 (8%) Query: 80 NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPG 139 N + A FE + G+PTP V+W R + L +Y + G +L I + P Sbjct: 642 NVTVNETSTASFECQASGDPTPTVTWYRGQTALTHGGRYVI------GQGTLTILRSNPS 695 Query: 140 DEGEYTCTARN 150 D GEY C N Sbjct: 696 DTGEYRCNVTN 706 Score = 41.1 bits (92), Expect = 0.021 Identities = 26/80 (32%), Positives = 33/80 (41%), Gaps = 6/80 (7%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P F+ ++ E T FECQ + GDP V W+ L H R Y G Sbjct: 633 PVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTHGGR----YVIGQGT 686 Query: 4033 MNFGWVYPEDSGEYLCRATN 4052 + P D+GEY C TN Sbjct: 687 LTILRSNPSDTGEYRCNVTN 706 Score = 40.3 bits (90), Expect = 0.037 Identities = 40/184 (21%), Positives = 64/184 (34%), Gaps = 16/184 (8%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXX 2463 G P V WF + + T + +TI V DEG ++C+ +N G Sbjct: 539 GSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAG----- 593 Query: 2464 XXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523 ++ E+ P ++ + Q + + + D P+F GP + Sbjct: 594 -AAEASANLYVKGESMTPRDLRPL----QTRDSKLVKLDVSASVPVFLD--AGPVNVTVN 646 Query: 2524 QHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583 + + GDP+ WY L G R+ G TL I +D G Y C Sbjct: 647 ETSTASFECQASGDPTPTVTWYRGQTALTHGGRY----VIGQGTLTILRSNPSDTGEYRC 702 Query: 2584 KAIN 2587 N Sbjct: 703 NVTN 706 Score = 38.7 bits (86), Expect = 0.11 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 9/148 (6%) Query: 1790 ELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQ 1849 +LG +T S+ + A+ + + E + +SR + V V P F T+ Sbjct: 373 QLGSGITVSSSGTLTFATAKKADEGEYFCSVVNSYLHASRSSSIALLTVWVR--PTFSTK 430 Query: 1850 LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTV 1909 T + E QS C YP P+ V W + + + + H SN +L I V Sbjct: 431 PQNTTVI-EHQSLLLICAATGYPMPS--VLWLKDNQAVDTNHVTLHSN----GSLSITRV 483 Query: 1910 YGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 D G Y+C A N G A S L VQ Sbjct: 484 LFSDRGSYSCVATNVAGSASSVATLTVQ 511 Score = 38.7 bits (86), Expect = 0.11 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 5/64 (7%) Query: 800 PTMRVEWYKDGRPITA-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858 P+ R+ WY+D R +T SR+T N G SL+I + D G+Y A N G TA Sbjct: 750 PSPRITWYRDRRVVTPDGSRVT--INGG--SLSIARVTRSDGGTYACAASNAAGMTSRTA 805 Query: 859 SIRV 862 ++ + Sbjct: 806 NLTI 809 Score = 37.9 bits (84), Expect = 0.20 Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 6/89 (6%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP F + T ++E QSA +C I P P++ E+ NG +L S RY+ SN Sbjct: 237 APHFQVHPSSTT-IAELQSAALQCHILGVPTPSVTWEFNSNG-LLDSPDRYQLSN----G 290 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSS 1931 +L + +G Y C N++G SS Sbjct: 291 SLYFKSANRTMAGVYKCTGTNSVGSVSSS 319 Score = 37.9 bits (84), Expect = 0.20 Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 G P PR+TW+++ +R++ + + T N +L + +SD G Y A N G + Sbjct: 748 GIPSPRITWYRD-RRVVTPDGSRV--TINGGSLSIARVTRSDGGTYACAASNAAGMTSRT 804 Query: 351 GYLAVESPTE 360 L ++ P + Sbjct: 805 ANLTIQVPPD 814 Score = 37.5 bits (83), Expect = 0.26 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 7/97 (7%) Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498 +V ++P F T+P++ VIE Q + C + V W K+ Q V H +H Sbjct: 420 TVWVRPTFSTKPQNT-TVIEHQSLLLICAATGYPMPS--VLWLKDNQAVDTNHV--TLHS 474 Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 G +L I ++ D G Y+C A N+ G+ LT Sbjct: 475 NG--SLSITRVLFSDRGSYSCVATNVAGSASSVATLT 509 Score = 37.1 bits (82), Expect = 0.35 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG-SRYKLTYDGMY 4165 P F P + T+ E + A C + G P P V W N N +++ RY+L+ +Y Sbjct: 238 PHFQVHPSSTTIAELQSAALQCHILGVPTPSVTWEFNSNGLLDSPDRYQLSNGSLY 293 Score = 37.1 bits (82), Expect = 0.35 Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 4/59 (6%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 V WLKD + V+ ++ +T N +L+I V D G Y+C A N G A++ A LT+ Sbjct: 456 VLWLKDNQAVD-TNHVTLHSNG---SLSITRVLFSDRGSYSCVATNVAGSASSVATLTV 510 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 5/71 (7%) Query: 3723 GDPTMRIDWFHNGRPFAT-GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781 G P+ RI W+ + R GSRV T+N +L I + D G Y C A+N G + Sbjct: 748 GIPSPRITWYRDRRVVTPDGSRV-TINGG---SLSIARVTRSDGGTYACAASNAAGMTSR 803 Query: 3782 TAKITCSAKRD 3792 TA +T D Sbjct: 804 TANLTIQVPPD 814 Score = 36.7 bits (81), Expect = 0.46 Identities = 46/203 (22%), Positives = 71/203 (34%), Gaps = 24/203 (11%) Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847 G++ C + S P + WFF N + + L I + D G + Sbjct: 528 GESHTVTCQFQGSPAPL--VTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFV 585 Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTE 2907 CK TN G+A S +L G ++ P+ L Q +++L K D Sbjct: 586 CKGTNPAGAAEASANLYVKG------ESMTPRDLRPL----QTRDSKLVK------LDVS 629 Query: 2908 YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFG 2967 P ++ + E E Q DP + WY L G R+ + G Sbjct: 630 ASVPVFLDAGPVNVTVNETSTASFECQA--SGDPTPTVTWYRGQTALTHGGRYVI----G 683 Query: 2968 FVTLDLVDVYERDSGIYTCKAYN 2990 TL ++ D+G Y C N Sbjct: 684 QGTLTILRSNPSDTGEYRCNVTN 706 Score = 36.7 bits (81), Expect = 0.46 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 5/56 (8%) Query: 2404 GDPTLKVEWFRNEKLIE-DSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 G P+ ++ W+R+ +++ D SR+T S++I+ V D G Y C ASN G Sbjct: 748 GIPSPRITWYRDRRVVTPDGSRVTINGG----SLSIARVTRSDGGTYACAASNAAG 799 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 6/93 (6%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP F + +AE Q+A + ++ V P + E+ NG+ +++ +R + + Sbjct: 237 APHFQVHPSSTTIAELQSAALQCHILGVPTPSVTWEFNSNGL-LDSPDR----YQLSNGS 291 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 L K N +G Y C N +G +V+SS +FV Sbjct: 292 LYFKSANRTMAGVYKCTGTNSVG-SVSSSPVFV 323 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 6/93 (6%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F+ ++ V E+Q+ G P V WL++ ++ ++ T+H G +L Sbjct: 425 PTFSTKPQNTTVIEHQSLLLICAA--TGYPMPSVLWLKDNQAVDTNH--VTLHSNG--SL 478 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 ++ V D G+Y+C A N G A + +TL VQ Sbjct: 479 SITRVLFSDRGSYSCVATNVAGSASSVATLTVQ 511 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 5/96 (5%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 Q P IT P S C P P R+ WY + +V+ T N Sbjct: 720 QVPAAITSFTAPRFAQLNGSTTLICLTRGIPSP--RITWYRDRRVVTPDGSRVTING--- 774 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 +L I V D G Y C A N G + L +Q Sbjct: 775 GSLSIARVTRSDGGTYACAASNAAGMTSRTANLTIQ 810 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 4/96 (4%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP NA G + + +G+P P+V+W K + ++ Y G Sbjct: 513 PPTVSGRPTNATRIVGESHTVTCQFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGG--I 570 Query: 131 LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQPE 164 L IK + DEG + C N G EA ++Y++ E Sbjct: 571 LTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKGE 606 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 8/84 (9%) Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704 +VT E FE + GDPT + W + ++ R+ G +L +L N Sbjct: 642 NVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTHGGRYV----IGQGTLTILRSNPS 695 Query: 705 DSGEYTCRAVSATGVAETKAVLHV 728 D+GEY C + G+A V H+ Sbjct: 696 DTGEYRCNVTN--GLATHVGVAHL 717 Score = 34.7 bits (76), Expect = 1.9 Identities = 43/171 (25%), Positives = 63/171 (36%), Gaps = 12/171 (7%) Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119 I+E Q A + ++ S+ E+ NG +++ R Y L T +G Sbjct: 249 IAELQSAALQCHILGVPTPSVTWEFNSNG-LLDSPDR----YQLSNGSLYFKSANRTMAG 303 Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179 Y C TN G S V F H + + + +G EC Sbjct: 304 VYKCTGTNSVGSVSSSPVFVGVAYFDFV---FHKHPSS-QNVTEGAPVSLECDPPNSYPI 359 Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230 + I W+ N Q ++ + I TVS G L A + D GEY C N Y Sbjct: 360 GVAITWFRNYQVVQLGSGI-TVSSSG--TLTFATAKKADEGEYFCSVVNSY 407 Score = 34.3 bits (75), Expect = 2.5 Identities = 14/41 (34%), Positives = 20/41 (48%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 P F + P TV E + C TG+P P V+WL + + Sbjct: 425 PTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQAV 465 Score = 34.3 bits (75), Expect = 2.5 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 5/65 (7%) Query: 2672 PNLKIEWFKNGVTLTT-GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 P+ +I W+++ +T G+R+ T + G +LSI + D G Y C A+N G TA Sbjct: 750 PSPRITWYRDRRVVTPDGSRV--TINGG--SLSIARVTRSDGGTYACAASNAAGMTSRTA 805 Query: 2731 SIKIE 2735 ++ I+ Sbjct: 806 NLTIQ 810 Score = 33.9 bits (74), Expect = 3.2 Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 5/89 (5%) Query: 1980 FGKPIKNAEVTEGHPVHLEATLTPVNDPT-MRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038 F K + VTEG PV LE P + P + + W+ N + VQ G T G L Sbjct: 332 FHKHPSSQNVTEGAPVSLECD-PPNSYPIGVAITWFRNYQVVQLGSGI-TVSSSG--TLT 387 Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067 A D G Y C N+ A +SS+ Sbjct: 388 FATAKKADEGEYFCSVVNSYLHASRSSSI 416 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 7/84 (8%) Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434 RP F+ QN I E Q+ C G P V W ++ + + D++ +T H G Sbjct: 424 RPTFSTKPQNTTVI-EHQSLLLICAA--TGYPMPSVLWLKDNQAV-DTNHVT-LHSNG-- 476 Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458 S++I+ V D G Y C A+N+ G Sbjct: 477 SLSITRVLFSDRGSYSCVATNVAG 500 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 5/69 (7%) Query: 3859 PKLRIEWYRNGKLL-PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKA 3917 P RI WYR+ +++ P G R + G SL I V D G Y C A N G A Sbjct: 750 PSPRITWYRDRRVVTPDGSR--VTINGG--SLSIARVTRSDGGTYACAASNAAGMTSRTA 805 Query: 3918 TISCKKLPD 3926 ++ + PD Sbjct: 806 NLTIQVPPD 814 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 9/72 (12%) Query: 2387 NIQEGQTAHFDC---RLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443 N+ EG +C P+G + + WFRN ++++ S IT + ++T + + Sbjct: 340 NVTEGAPVSLECDPPNSYPIG---VAITWFRNYQVVQLGSGITVSSS---GTLTFATAKK 393 Query: 2444 EDEGVYMCRASN 2455 DEG Y C N Sbjct: 394 ADEGEYFCSVVN 405 Score = 33.5 bits (73), Expect = 4.3 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 6/98 (6%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F T+ ++ TV E + + C P + W ++ + + + H T++ G SL Sbjct: 425 PTFSTKPQNTTVIEHQSLLLICAATGYPMPS--VLWLKDNQAVDTNHV--TLHSNG--SL 478 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927 I V D G Y C A N G + AT++ + P + Sbjct: 479 SITRVLFSDRGSYSCVATNVAGSASSVATLTVQVPPTV 516 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198 P ++ W + Q + H T H G +L I D G+Y C ATN G A + T Sbjct: 452 PMPSVLWLKDNQAVDTNHV--TLHSNG--SLSITRVLFSDRGSYSCVATNVAGSASSVAT 507 Query: 2199 LKV 2201 L V Sbjct: 508 LTV 510 Score = 33.1 bits (72), Expect = 5.7 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 4/61 (6%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 P + W +N+ + T + + H S SL IT D G Y+C ATN GSA++ + Sbjct: 452 PMPSVLWLKDNQAVD--TNHVTLH--SNGSLSITRVLFSDRGSYSCVATNVAGSASSVAT 507 Query: 2863 L 2863 L Sbjct: 508 L 508 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066 P+ R+ WY + R V + T + G +L I D GTY C A+NA G T++ Sbjct: 750 PSPRITWYRDRRVVTPDGS-RVTINGG--SLSIARVTRSDGGTYACAASNAAGMTSRTAN 806 Query: 2067 VKV 2069 + + Sbjct: 807 LTI 809 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 3/80 (3%) Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765 +V EG PV +C + I WF N + GS + T++ G L D Sbjct: 340 NVTEGAPVSLECDPPNSYPIGVAITWFRNYQVVQLGSGI-TVSSSG--TLTFATAKKADE 396 Query: 3766 GEYTCRATNKWGSATTTAKI 3785 GEY C N + A+ ++ I Sbjct: 397 GEYFCSVVNSYLHASRSSSI 416 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G P + WLK+ Q+++ + ++ G SL + + D G Y+C A + G A + Sbjct: 450 GYPMPSVLWLKDNQAVDTNH--VTLHSNG--SLSITRVLFSDRGSYSCVATNVAGSASSV 505 Query: 724 AVLHVTPRATI 734 A L V T+ Sbjct: 506 ATLTVQVPPTV 516 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 3/62 (4%) Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139 + Q N + T H G +L I V D G Y+ VA N AG A A++TV+ Sbjct: 458 WLKDNQAVDTNHV-TLHSNG--SLSITRVLFSDRGSYSCVATNVAGSASSVATLTVQVPP 514 Query: 1140 SI 1141 ++ Sbjct: 515 TV 516 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/92 (22%), Positives = 43/92 (46%), Gaps = 5/92 (5%) Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS-NKHEIITTH 318 L + P P ++ + E A Q + G P P VTW N L++S +++++ Sbjct: 232 LPAIDAPHFQVHPSSTTIAELQSAALQCHILGVPTPSVTWEFNSNGLLDSPDRYQL---- 287 Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 ++ +L ++ ++ +G Y N G + +S Sbjct: 288 SNGSLYFKSANRTMAGVYKCTGTNSVGSVSSS 319 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 5/59 (8%) Query: 2803 PTLKIEWFFN-NKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860 PT + W FN N L S RY+ ++ SL +G+Y C TNS GS ++S Sbjct: 265 PTPSVTWEFNSNGLLDSPDRYQLSNG----SLYFKSANRTMAGVYKCTGTNSVGSVSSS 319 Score = 32.3 bits (70), Expect = 9.9 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 3/97 (3%) Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873 G +S +P + F S V E V EC + I W+RN +++ Sbjct: 314 GSVSSSPVFVGVAYFDFVFHKHPSSQNVTEGAPVSLECDPPNSYPIGVAITWFRNYQVVQ 373 Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910 G TV G +L D GEY C VN + Sbjct: 374 LGSGI-TVSSSG--TLTFATAKKADEGEYFCSVVNSY 407 Score = 32.3 bits (70), Expect = 9.9 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 6/98 (6%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 +TV P FS N +E ++ L C G V W + + + T H Sbjct: 419 LTVWVRPTFSTKPQNTTVIEHQSLLLICAA--TGYPMPSVLWLKDNQAVDTNH----VTL 472 Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 +L + V D G Y+C ATN G A + L V Sbjct: 473 HSNGSLSITRVLFSDRGSYSCVATNVAGSASSVATLTV 510 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P V W KD + + + ++ + G SL+I + D GSY+ A N G A S A+ Sbjct: 452 PMPSVLWLKDNQAVDTNH--VTLHSNG--SLSITRVLFSDRGSYSCVATNVAGSASSVAT 507 Query: 860 IRVAARSTVT 869 + V TV+ Sbjct: 508 LTVQVPPTVS 517 Score = 32.3 bits (70), Expect = 9.9 Identities = 14/35 (40%), Positives = 22/35 (62%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 +LSI + D G Y+C ATN+ G A S A++ ++ Sbjct: 477 SLSITRVLFSDRGSYSCVATNVAGSASSVATLTVQ 511 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 + WY + + +T T + +L IA V D G Y A NAAG +A++T++ Sbjct: 754 ITWYRDRRVVTPDGSRVTINGG---SLSIARVTRSDGGTYACAASNAAGMTSRTANLTIQ 810 >SB_19226| Best HMM Match : I-set (HMM E-Value=0) Length = 1500 Score = 92.7 bits (220), Expect = 7e-18 Identities = 106/429 (24%), Positives = 158/429 (36%), Gaps = 52/429 (12%) Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442 T+ T E A ++V P P T + + E A + G P P Sbjct: 446 TAVNTLTGETHASNPAKLVVVPSSSPFAPRMTSLVHNLTLIAGETAVLQCTAAGSPTPYF 505 Query: 4443 KWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502 +W + + + + L+I D A + A N G+ + L V Sbjct: 506 RWLKSGKSLTMGGRMSVIAGGS---LMIESTMASDEANYTCQAVNNVGSVHMAIYLEV-- 560 Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSG-QLVRLDTKVTGTKPIDVYWLKNGKKV-QPDIRN 4560 IVP +F + G ++ VTG + W +N + + QP R Sbjct: 561 --------IVPITFKERPKPQAAQVGFPRKNMECDVTGEPEPKITWYQNAQSLGQPKGRI 612 Query: 4561 KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAAN 4620 I + D L+I Y QD+G Y+CVA N + AE P Sbjct: 613 SIRDND----LVIATVYGQDNGVYQCVADNGRELVQSSAEFYAGFSVPTFNP-------- 660 Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGD-KLIKPSKYFQMSRTADEY 4678 P+I I+ G ++ +C++ P P VQWY D L Y + + Sbjct: 661 GTPDI-------ILYPGTPLQITCEVSAIPYPRDVQWYHDDIPLTGGHDYIITAMPGTKR 713 Query: 4679 TLRISE-----AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV- 4732 + R+S+ D G+YKCVA N+AG K+ V P P +T R V Sbjct: 714 SSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVYVRGP------PNITSFRSSVTG 767 Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792 +G + P I W R G IP + +N LLIGN + D+G +T Sbjct: 768 VQGDTISLPCRAKGFPPPVITWSRSGQTIP----YDRRQSIDNGTLLIGNVQKSDSGKYT 823 Query: 4793 CRATTAAGQ 4801 C A AG+ Sbjct: 824 CTAVNTAGE 832 Score = 86.2 bits (204), Expect = 6e-16 Identities = 98/389 (25%), Positives = 148/389 (38%), Gaps = 46/389 (11%) Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490 E + GEP P I WY +N P +I L+I V+ +D+ V+ VA+N Sbjct: 585 ECDVTGEPEPKITWY-QNAQSLGQPKGRISIRDND--LVIATVYGQDNGVYQCVADNGRE 641 Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLK 4549 + SA G P+F ++ + G +++ +V+ P DV W Sbjct: 642 LVQSSAEFYA---------GFSVPTFNPGTPDIILYPGTPLQITCEVSAIPYPRDVQWYH 692 Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQ------DSGKYECVAINSAGEARCDAECVV 4603 + + I GT L + DSG+Y+CVA N+AG A E V+ Sbjct: 693 DDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSA----EQVI 748 Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663 + PP I +G I C+ G P P + W + + I Sbjct: 749 KV------------YVRGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTI 796 Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA 4723 + ++ D TL I D G Y C A N+AG + VT P Sbjct: 797 P----YDRRQSIDNGTLLIGNVQKSDSGKYTCTAVNTAGE-----RDSVTMTVSIVVSPR 847 Query: 4724 LTPLRDIVVYEGQPAQFKTQITSKIKP-TIQWLREGALIPETP-DFQMIHEGNNAVLLIG 4781 +TP V EGQ + + P I WLR+G + P D +++ + L I Sbjct: 848 ITPFMWAPVDEGQREHYTCVVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIP 907 Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 + G +TC AG SA+L+V Sbjct: 908 QVMQRHQGVYTCIVGNRAGIARHSAQLIV 936 Score = 79.4 bits (187), Expect = 7e-14 Identities = 74/306 (24%), Positives = 125/306 (40%), Gaps = 34/306 (11%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 P T N+ + +G+ L G+ WLK+GK + R ++ +L+I Sbjct: 474 PRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIAGG---SLMI 530 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDK 4632 D Y C A+N+ G V +P T K++PKPQ P + +E Sbjct: 531 ESTMASDEANYTCQAVNNVGSVHMAIYLEVIVPITFKERPKPQAAQVGFPRKNME----- 585 Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692 C + G+P P + WY+ + + K R D L I+ + +D G Sbjct: 586 -----------CDVTGEPEPKITWYQNAQSLGQPKGRISIRDND---LVIATVYGQDNGV 631 Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT- 4751 Y+CVA N GR V + + TP DI++Y G P Q ++++ P Sbjct: 632 YQCVADN--GRELVQSSAEFYAGFSVPTFNPGTP--DIILYPGTPLQITCEVSAIPYPRD 687 Query: 4752 IQWLREGALIPETPDFQMIH----EGNNAVLLIGNTYEE--DTGTFTCRATTAAGQVETS 4805 +QW + + D+ + + ++ + + T D+G + C A+ AAG E Sbjct: 688 VQWYHDDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQV 747 Query: 4806 AKLVVK 4811 K+ V+ Sbjct: 748 IKVYVR 753 Score = 67.3 bits (157), Expect = 3e-10 Identities = 63/209 (30%), Positives = 90/209 (43%), Gaps = 17/209 (8%) Query: 369 QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFI 427 Q + D + + E P F D + G + C V+ PYP +V W+ Sbjct: 633 QCVADNGRELVQSSAEFYAGFSVPTFNPGTPDIILYPGTPLQITCEVSAIPYPRDVQWYH 692 Query: 428 NDRQIRDDYNHKILV-----NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 +D + +++ I S L T V+++DSG CVA N +G V Sbjct: 693 DDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSAE-----QV 747 Query: 483 IEKEQVVAPKFVERF-STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541 I K V P + F S++ +G+ + L RA G P P ITW + G IP + R Sbjct: 748 I-KVYVRGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSG-QTIPY-DRRQSI 804 Query: 542 DGGASTLDIPRAKASDAAWYQCTAQNVAG 570 D G TL I + SD+ Y CTA N AG Sbjct: 805 DNG--TLLIGNVQKSDSGKYTCTAVNTAG 831 Score = 65.3 bits (152), Expect = 1e-09 Identities = 56/176 (31%), Positives = 72/176 (40%), Gaps = 12/176 (6%) Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464 +G CR G P P +TW + + I D I N L+I NV SDSG T Sbjct: 769 QGDTISLPCRAKGFPPPVITWSRSGQTIPYDRRQSI-----DNGTLLIGNVQKSDSGKYT 823 Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN-ARAVGTPTPRIT 523 C A N +GE R +V +V + F V EG+ A G IT Sbjct: 824 CTAVNTAGE-----RDSVTMTVSIVVSPRITPFMWAPVDEGQREHYTCVVAEGDMPCNIT 878 Query: 524 WQKDGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 W +DG P+ P +L I T S+L IP+ Y C N AG A+L Sbjct: 879 WLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQL 934 Score = 55.6 bits (128), Expect = 9e-07 Identities = 46/175 (26%), Positives = 71/175 (40%), Gaps = 15/175 (8%) Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471 +C VTG P P++TW+ N + + +I + ++ L+I V D+GV CVA N Sbjct: 585 ECDVTGEPEPKITWYQNAQSLGQP-KGRISIRDND---LVIATVYGQDNGVYQCVADN-- 638 Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR-ITWQKDGVP 530 G Q V P F + + G P+ + P PR + W D +P Sbjct: 639 GRELVQSSAEFYAGFSV--PTFNPGTPDIILYPGTPLQITCEVSAIPYPRDVQWYHDDIP 696 Query: 531 IIPNPELRIHTDGGA------STLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579 + + I G S L +D+ Y+C A N AGS ++Y Sbjct: 697 LTGGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVY 751 Score = 50.4 bits (115), Expect = 3e-05 Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 7/126 (5%) Query: 450 LMITNVTLSDSGVVT--CVARNKSGET--AFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505 L+ITN D + +GET + +L V+ AP+ L + G Sbjct: 429 LVITNAHAEDENSMYHWTAVNTLTGETHASNPAKLVVVPSSSPFAPRMTSLVHNLTLIAG 488 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 E VL A G+PTP W K G + + + G +L I ASD A Y C A Sbjct: 489 ETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIAGG---SLMIESTMASDEANYTCQA 545 Query: 566 QNVAGS 571 N GS Sbjct: 546 VNNVGS 551 Score = 49.2 bits (112), Expect = 8e-05 Identities = 58/248 (23%), Positives = 88/248 (35%), Gaps = 18/248 (7%) Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI-SEKALAP 392 G YT++ P+G +V + A E Y + +T + + + S AP Sbjct: 419 GRYTIM---PSGDLVITNAHA-EDENSMYHWTAVNTLTGETHASNPAKLVVVPSSSPFAP 474 Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452 + + + + G+ C G P P W + + + ++ S LMI Sbjct: 475 RMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIAGGS----LMI 530 Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP-VVLN 511 + SD TC A N G L VI V F ER + G P + Sbjct: 531 ESTMASDEANYTCQAVNNVGSVHMAIYLEVI-----VPITFKERPKPQAAQVGFPRKNME 585 Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 G P P+ITW ++ + P+ RI + L I D YQC A N Sbjct: 586 CDVTGEPEPKITWYQN-AQSLGQPKGRISIRD--NDLVIATVYGQDNGVYQCVADNGREL 642 Query: 572 TATRARLY 579 + A Y Sbjct: 643 VQSSAEFY 650 Score = 48.4 bits (110), Expect = 1e-04 Identities = 58/231 (25%), Positives = 89/231 (38%), Gaps = 17/231 (7%) Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDA 3627 + E H+ C ++ D + W +GKPL + I F+ L I V QR Sbjct: 856 VDEGQREHYTC-VVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914 Query: 3628 GLYTCKATNRHGEATVSCKLQV--KGRQGIILEPQL----PSHFKSGTESIQKLEETLHK 3681 G+YTC NR G A S +L V R +L L S G S + Sbjct: 915 GVYTCIVGNRAGIARHSAQLIVYDNHRFQQLLNGTLVIRNASKRDEGRYSCHAYNGVVGT 974 Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 + + P V + V G + F C +G+ + + WF+ + Sbjct: 975 PVSRQV-SLVVHVPAVIVSPPSDRSVEVFGEMAFSC--VAIGNLPIMLSWFNGSKQMVDS 1031 Query: 3742 SRV----HTLNDFGFI--ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786 SRV +T ++ + L + + D EY+CR N++G T KIT Sbjct: 1032 SRVQIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKIT 1082 Score = 47.6 bits (108), Expect = 2e-04 Identities = 42/164 (25%), Positives = 67/164 (40%), Gaps = 20/164 (12%) Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629 TL+I A +D G+Y C A N VV P ++ + + P I+ P Sbjct: 949 TLVIRNASKRDEGRYSCHAYNG----------VVGTPVSRQV----SLVVHVPAVIVSPP 994 Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR-TADEY-----TLRIS 4683 D+ V + FSC +G + W+ G K + S Q+ R T D TL +S Sbjct: 995 SDRSVEVFGEMAFSCVAIGNLPIMLSWFNGSKQMVDSSRVQIMRYTKDNAHLVNGTLHVS 1054 Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727 + D +Y C N GR K+ V + ++P ++ + Sbjct: 1055 DLRLWDTKEYSCRVGNQFGRDEKTFKITVQESPSNPSVPRVSDI 1098 Score = 44.8 bits (101), Expect = 0.002 Identities = 42/152 (27%), Positives = 61/152 (40%), Gaps = 12/152 (7%) Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140 VI W +G+TI R + L I + +DSG Y+C A N G+ + SV + Sbjct: 786 VITWSRSGQTIPYDRR----QSIDNGTLLIGNVQKSDSGKYTCTAVNTAGERD-SVTMTV 840 Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 S PR T + + +GQ H+ C V D P I W +G+P+ Sbjct: 841 ---SIVVSPRITPFMW--APVDEGQREHYTCVVAEGDMP-CNITWLRDGKPLYSIPGDLE 894 Query: 3201 VSDFGFV-VLDIAYTQNHDSGEYVCRAYNKYG 3231 + F+ L I G Y C N+ G Sbjct: 895 IMTSQFISSLSIPQVMQRHQGVYTCIVGNRAG 926 Score = 44.0 bits (99), Expect = 0.003 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 6/84 (7%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP + QG + +G P PV++W+R + Y R + G + Sbjct: 755 PPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTI----PYDRRQSIDNG--T 808 Query: 131 LLIKQIGPGDEGEYTCTARNQYGE 154 LLI + D G+YTCTA N GE Sbjct: 809 LLIGNVQKSDSGKYTCTAVNTAGE 832 Score = 43.6 bits (98), Expect = 0.004 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P++ N L G A Q +G+P P W K+G+ L + +I +L + Sbjct: 474 PRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIA---GGSLMI 530 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 +T SD +YT A N G + + YL V P Sbjct: 531 ESTMASDEANYTCQAVNNVGSVHMAIYLEVIVP 563 Score = 43.6 bits (98), Expect = 0.004 Identities = 36/116 (31%), Positives = 52/116 (44%), Gaps = 12/116 (10%) Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176 DSG Y C A+N G AE +K+ +G P T+ ++ G++ G + C Sbjct: 729 DSGEYKCVASNAAGSAEQVIKVYV----RGP-PNITSFRSSVTGVQ-GDTISLPCRAKGF 782 Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 P I W +GQ + + R D G ++ I Q DSG+Y C A N GE Sbjct: 783 PPP--VITWSRSGQTIPYDRRQSI--DNGTLL--IGNVQKSDSGKYTCTAVNTAGE 832 Score = 43.6 bits (98), Expect = 0.004 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 4/81 (4%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PP I + +G + G P P +TW ++GQ + + I ++ TL Sbjct: 755 PPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTIPYDRRQSI----DNGTLL 810 Query: 325 VRNTQKSDSGHYTLLAENPNG 345 + N QKSDSG YT A N G Sbjct: 811 IGNVQKSDSGKYTCTAVNTAG 831 Score = 42.7 bits (96), Expect = 0.007 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 6/94 (6%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 APR + ++ T ++ G++A +C P P R W +GK L G R Sbjct: 473 APRMTSLVHNLTLIA-GETAVLQCTAAGSPTPYFR--WLKSGKSLTMGGRMSV---IAGG 526 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 +L I + D YTC+A+NN+G +I L V Sbjct: 527 SLMIESTMASDEANYTCQAVNNVGSVHMAIYLEV 560 Score = 42.7 bits (96), Expect = 0.007 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 5/79 (6%) Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251 G+ L+C G PT W +G+S+T+G R +L I ++D YT Sbjct: 488 GETAVLQCTAA--GSPTPYFRWLKSGKSLTMGGRMSV---IAGGSLMIESTMASDEANYT 542 Query: 1252 VRAVNHLGSAHTSAIVRVI 1270 +AVN++GS H + + VI Sbjct: 543 CQAVNNVGSVHMAIYLEVI 561 Score = 41.9 bits (94), Expect = 0.012 Identities = 61/267 (22%), Positives = 100/267 (37%), Gaps = 27/267 (10%) Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737 T +R+ +T+ PR T + +D EG H+ C V GD I W +G+P Sbjct: 829 TAGERDSVTMTVSIVVSPRITPFMWAPVD--EGQREHYTCVVAE-GDMPCNITWLRDGKP 885 Query: 3738 -FATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796 ++ + + +L I + R G YTC N+ G A +A++ Sbjct: 886 LYSIPGDLEIMTSQFISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQLIVYDNHRF--- 942 Query: 3797 SQLPQG-MSGEKIKELERGRIS--------DAPKEEP---IVSTPPKFITQIKSHTVEES 3844 QL G + + + GR S P +V P ++ +VE Sbjct: 943 QQLLNGTLVIRNASKRDEGRYSCHAYNGVVGTPVSRQVSLVVHVPAVIVSPPSDRSVEVF 1002 Query: 3845 EGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR---YRTVYDMGFV---SLDILYVYAED 3898 + F C V P + + W+ K + R R D + +L + + D Sbjct: 1003 GEMAFSC-VAIGNLP-IMLSWFNGSKQMVDSSRVQIMRYTKDNAHLVNGTLHVSDLRLWD 1060 Query: 3899 SGEYICRAVNDFGEDFTKATISCKKLP 3925 + EY CR N FG D I+ ++ P Sbjct: 1061 TKEYSCRVGNQFGRDEKTFKITVQESP 1087 Score = 41.1 bits (92), Expect = 0.021 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 5/94 (5%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP+ + +HN+ + G L+C G T W +GK + G R + Sbjct: 473 APRMTSLVHNLTLIAGETAVLQC--TAAGSPTPYFRWLKSGKSLTMGGRMS---VIAGGS 527 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 L + S D YTCQA N +G + L VI Sbjct: 528 LMIESTMASDEANYTCQAVNNVGSVHMAIYLEVI 561 Score = 41.1 bits (92), Expect = 0.021 Identities = 53/237 (22%), Positives = 88/237 (37%), Gaps = 22/237 (9%) Query: 1589 IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA-LDIMSCLPEDS 1647 + EGQR H+ ++ D + W + KPL S E F++ L I + Sbjct: 856 VDEGQREHYTC-VVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914 Query: 1648 GTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRH------- 1700 G YTC N G A S IV+ + + + + R D +Y H Sbjct: 915 GVYTCIVGNRAGIARHSAQLIVYDNHR-FQQLLNGTLVIRNASKRDEGRYSCHAYNGVVG 973 Query: 1701 ---SAQDEVITQAP-VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756 S Q ++ P V P D V F + +G+ + + W + S Sbjct: 974 TPVSRQVSLVVHVPAVIVSPPSDRSVEVFGEMAFSC--VAIGNLPIMLSWFNGSKQMVDS 1031 Query: 1757 NRLTTMH---DFGYV---ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807 +R+ M D ++ L++ + D+ Y+CR N+ G + + VQ S Sbjct: 1032 SRVQIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQESPS 1088 Score = 40.3 bits (90), Expect = 0.037 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 1/65 (1%) Query: 4442 IKWYRENFPIKNSP-DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500 I W R+ P+ + P D +I T S L I QV V+ + NR G A+ SA L+V Sbjct: 877 ITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQLIV 936 Query: 4501 EEKRR 4505 + R Sbjct: 937 YDNHR 941 Score = 39.9 bits (89), Expect = 0.049 Identities = 35/103 (33%), Positives = 45/103 (43%), Gaps = 7/103 (6%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885 V PP + S T + + + CR K P I W R+G+ +P R D G Sbjct: 752 VRGPPNITSFRSSVTGVQGDTISLPCRA--KGFPPPVITWSRSGQTIPYDRRQSI--DNG 807 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGE-DFTKATISCKKLPDI 3927 +L I V DSG+Y C AVN GE D T+S P I Sbjct: 808 --TLLIGNVQKSDSGKYTCTAVNTAGERDSVTMTVSIVVSPRI 848 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 5/94 (5%) Query: 69 PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128 P P + N G A + G+PTP W + L + S+ Sbjct: 471 PFAPRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSV-----IAG 525 Query: 129 VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162 SL+I+ DE YTC A N G ++Y++ Sbjct: 526 GSLMIESTMASDEANYTCQAVNNVGSVHMAIYLE 559 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 6/94 (6%) Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744 + + P PR T + N+ + G C G PT W +G+ G R+ Sbjct: 464 VVVPSSSPFAPRMT-SLVHNLTLIAGETAVLQCTA--AGSPTPYFRWLKSGKSLTMGGRM 520 Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778 + +L I+ A D YTC+A N GS Sbjct: 521 SVIAGG---SLMIESTMASDEANYTCQAVNNVGS 551 Score = 37.9 bits (84), Expect = 0.20 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 7/93 (7%) Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY------RTSNDFGFAALDILTV 1909 L G C + P P V+WY + L GH Y T + L V Sbjct: 667 LYPGTPLQITCEVSAIPYPR-DVQWYHDDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAV 725 Query: 1910 YGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942 DSGEY C A N G A I++ V+ +I Sbjct: 726 SMADSGEYKCVASNAAGSAEQVIKVYVRGPPNI 758 Score = 37.9 bits (84), Expect = 0.20 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 6/86 (6%) Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 + P IT +G + CR + +P P + W +G+ + R N Sbjct: 753 RGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPV--ITWSRSGQTIPYDRRQSIDN---- 806 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQ 1927 L I V DSG+YTC A+N G+ Sbjct: 807 GTLLIGNVQKSDSGKYTCTAVNTAGE 832 Score = 37.9 bits (84), Expect = 0.20 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 9/101 (8%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP SVT ++G I R + G P I W ++GQ+I R SI G + Sbjct: 755 PPNITSFRSSVTGVQGDTISLPCRAK--GFPPPVITWSRSGQTIPYDRR-QSIDN-GTLL 810 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAV---LHVTPRAT 733 + ++ DSG+YTC AV+ G ++ + + V+PR T Sbjct: 811 IG--NVQKSDSGKYTCTAVNTAGERDSVTMTVSIVVSPRIT 849 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 4/82 (4%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G PT WLK+G+S+ R S+ G SL + S D YTC+AV+ G Sbjct: 499 GSPTPYFRWLKSGKSLTMGGRM-SVIAGG--SLMIESTMASDEANYTCQAVNNVGSVHMA 555 Query: 724 AVLHVTPRATIERTSQHPETLQ 745 L V T + + P+ Q Sbjct: 556 IYLEVIVPITFKERPK-PQAAQ 576 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 793 QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852 Q T PT W K G+ +T R+ S+ G SL I A D +YT +AVN +G Sbjct: 494 QCTAAGSPTPYFRWLKSGKSLTMGGRM-SVIAGG--SLMIESTMASDEANYTCQAVNNVG 550 Score = 36.7 bits (81), Expect = 0.46 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 6/100 (6%) Query: 263 VSPPKIAQKPRNSKLQEGADAQ-FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321 + P ++P+ Q G + + ++G P P++TW++N Q L K I N Sbjct: 561 IVPITFKERPKPQAAQVGFPRKNMECDVTGEPEPKITWYQNAQSL-GQPKGRISIRDN-- 617 Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSG--YLAVESPT 359 L + D+G Y +A+N + +S Y PT Sbjct: 618 DLVIATVYGQDNGVYQCVADNGRELVQSSAEFYAGFSVPT 657 Score = 36.7 bits (81), Expect = 0.46 Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 9/101 (8%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 + P T +S V+G + L + + P I W ++G T+ R + D G Sbjct: 753 RGPPNITSFRSSVTGVQGDTISLPCRAKGFPPP--VITWSRSGQTIPYDRR--QSIDNG- 807 Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVS---TASIKIEDR 2737 TL I +++ DSG YTC A N GE S T SI + R Sbjct: 808 -TLLIGNVQKSDSGKYTCTAVNTAGERDSVTMTVSIVVSPR 847 Score = 36.7 bits (81), Expect = 0.46 Identities = 49/235 (20%), Positives = 90/235 (38%), Gaps = 17/235 (7%) Query: 921 IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV-ALTIKSVTVHDA 979 + EG H+ + GD + WL+DG+P+ + ++ +L+I V Sbjct: 856 VDEGQREHYTCVVAE-GDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914 Query: 980 GHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKI 1039 G YTC N G A SA L IV + + + + D RYS V Sbjct: 915 GVYTCIVGNRAGIARHSAQL-IVYDNHRFQQLLNGTLVIRNASKRDEGRYSCHAYNGVVG 973 Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQ--------SDLTMTVEWYFNGKQITSANR 1091 T R + + ++ + V + +L + + W+ KQ+ ++R Sbjct: 974 TPVSRQVSLVVHVPAVIVSPPSDRSVEVFGEMAFSCVAIGNLPIMLSWFNGSKQMVDSSR 1033 Query: 1092 IQTYH---DFGYV---ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140 +Q D ++ L ++ +R D+ Y+ N G + + +TV+ S Sbjct: 1034 VQIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQESPS 1088 Score = 36.7 bits (81), Expect = 0.46 Identities = 49/233 (21%), Positives = 89/233 (38%), Gaps = 21/233 (9%) Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA-LDLLSVYPEDSGV 1382 EG H C + GD + W +GKP+ + +++ L + V GV Sbjct: 858 EGQREHYTCVVAE-GDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQGV 916 Query: 1383 YTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYK---KTDIIDES 1439 YTC N+ G A S L ++ + + + + + D RY ++ Sbjct: 917 YTCIVGNRAGIARHSAQL-IVYDNHRFQQLLNGTLVIRNASKRDEGRYSCHAYNGVVGTP 975 Query: 1440 VTIK-------PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492 V+ + P + P S +V + F C + + + + WF + + R Sbjct: 976 VSRQVSLVVHVPAVIVSPPSDRSVEVFGEMAFSC--VAIGNLPIMLSWFNGSKQMVDSSR 1033 Query: 1493 ---FRPIHDFGYV---ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539 R D ++ L + DL D+ Y+CR N G DE + ++T + + Sbjct: 1034 VQIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQES 1086 Score = 36.3 bits (80), Expect = 0.61 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 8/120 (6%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG------SRVHTLN 3748 P F D I P G P+ C V + P + W+H+ P G + T Sbjct: 656 PTFNPGTPDIILYP-GTPLQITCEVSAIPYPR-DVQWYHDDIPLTGGHDYIITAMPGTKR 713 Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808 L + D+GEY C A+N GSA K+ +I G+ G+ I Sbjct: 714 SSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVYVRGPPNITSFRSSVTGVQGDTI 773 Score = 36.3 bits (80), Expect = 0.61 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%) Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158 EQV++ R PP S +VT +G+ CR G P P + W +G TI R Sbjct: 745 EQVIKVY-VRGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTIPYDRRQS 803 Query: 4159 LTYDGMYHFDIPKTRQYDTGK 4179 + + ++ K+ D+GK Sbjct: 804 IDNGTLLIGNVQKS---DSGK 821 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 2/89 (2%) Query: 1722 VAENQAAHFEARLIPVGDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMKYVNPEDS 1780 V E Q H+ ++ GD + WLR+G P+ L M +L++ V Sbjct: 856 VDEGQREHYTC-VVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914 Query: 1781 GTYTCRAINELGEAVTSSTLFVQSKASLQ 1809 G YTC N G A S+ L V Q Sbjct: 915 GVYTCIVGNRAGIARHSAQLIVYDNHRFQ 943 Score = 36.3 bits (80), Expect = 0.61 Identities = 49/230 (21%), Positives = 84/230 (36%), Gaps = 16/230 (6%) Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPEDSGE 3492 EG+ H+ + D P + W +GK L + F+ L I G Sbjct: 858 EGQREHYTCVVAEGDMP-CNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQGV 916 Query: 3493 YLCRAYNNYGEAVTTASMKVQGKRNI--ILESQLPKGMEGTIDKIA-ALEGYSGTVDTLT 3549 Y C N G A +A + V +L L D+ + Y+G V T Sbjct: 917 YTCIVGNRAGIARHSAQLIVYDNHRFQQLLNGTLVIRNASKRDEGRYSCHAYNGVVGTPV 976 Query: 3550 PEAES---GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606 S P + PSD + F C + + + + + WF+ K ++ SRV Sbjct: 977 SRQVSLVVHVPAVIVSPPSDRSVEVFGEMAFSC--VAIGNLPIMLSWFNGSKQMVDSSRV 1034 Query: 3607 KTI---NDFGFVI---LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 + + D ++ L + + D Y+C+ N+ G + K+ V+ Sbjct: 1035 QIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQ 1084 Score = 35.9 bits (79), Expect = 0.80 Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 4/79 (5%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPS--GTRYKSTHDFSYVSLDITHTYEEDSG 2844 EG H+ C V D I W + KPL S G T F SL I + G Sbjct: 858 EGQREHYTCVVAEG-DMPCNITWLRDGKPLYSIPGDLEIMTSQF-ISSLSIPQVMQRHQG 915 Query: 2845 IYTCKATNSKGSATTSGSL 2863 +YTC N G A S L Sbjct: 916 VYTCIVGNRAGIARHSAQL 934 Score = 35.5 bits (78), Expect = 1.1 Identities = 20/63 (31%), Positives = 27/63 (42%) Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 VV S + P SL +T+ GE A C G P P WL +G ++ G R + Sbjct: 464 VVVPSSSPFAPRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVI 523 Query: 4161 YDG 4163 G Sbjct: 524 AGG 526 Score = 35.1 bits (77), Expect = 1.4 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 6/84 (7%) Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478 AP T + N+ L GE A + T P W +GKSL G R G + Sbjct: 473 APRMTSLVHNL-TLIAGETAVLQC--TAAGSPTPYFRWLKSGKSLTMGGRMSVIAG-GSL 528 Query: 3479 ILEISPTYPEDSGEYLCRAYNNYG 3502 ++E T D Y C+A NN G Sbjct: 529 MIE--STMASDEANYTCQAVNNVG 550 Score = 35.1 bits (77), Expect = 1.4 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G P+ F W +G L MG R +L I S +A+D Y C+A+N G Sbjct: 499 GSPTPYFRWLKSGKSLTMGGRMSV---IAGGSLMIESTMASDEANYTCQAVNNVG 550 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 7/101 (6%) Query: 1293 DAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP 1352 +AA +QV + + V P + ++ V+G + L CR + G + W +G+ Sbjct: 739 NAAGSAEQVIK-VYVRGPPNITSFRSSVTGVQGDTISLPCRAK--GFPPPVITWSRSGQT 795 Query: 1353 IKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393 I R D L + +V DSG YTC A N GE Sbjct: 796 IPYDRR----QSIDNGTLLIGNVQKSDSGKYTCTAVNTAGE 832 Score = 35.1 bits (77), Expect = 1.4 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-MTISHVRDEDE 2446 + EGQ H+ C ++ GD + W R+ K + + ++S ++I V + Sbjct: 856 VDEGQREHYTC-VVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914 Query: 2447 GVYMCRASNLLG 2458 GVY C N G Sbjct: 915 GVYTCIVGNRAG 926 Score = 34.7 bits (76), Expect = 1.9 Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 18/118 (15%) Query: 3545 VDTLTPEAESGNPPEFTTTPS-------------DLILSENSSAHFECRLIPVNDSSMRV 3591 V+TLT E + NP + PS +L L +A +C + Sbjct: 448 VNTLTGETHASNPAKLVVVPSSSPFAPRMTSLVHNLTLIAGETAVLQC--TAAGSPTPYF 505 Query: 3592 EWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 W +GK L G R+ I G +++E D YTC+A N G ++ L+V Sbjct: 506 RWLKSGKSLTMGGRMSVIAG-GSLMIE--STMASDEANYTCQAVNNVGSVHMAIYLEV 560 Score = 34.7 bits (76), Expect = 1.9 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%) Query: 2625 AMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684 A N + V + AP T+ + + L+ G+ L+ P + W K+G + Sbjct: 457 ASNPAKLVVVPSSSPFAPRMTSLVHNLT-LIAGETAVLQCTAAGSPTPYFR--WLKSGKS 513 Query: 2685 LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724 LT G R+ S G +L I S D YTC+A N +G Sbjct: 514 LTMGGRM-SVIAGG--SLMIESTMASDEANYTCQAVNNVG 550 Score = 34.7 bits (76), Expect = 1.9 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G T WLK G+ + R++ +L I+S D +YTC+A N +G + Sbjct: 499 GSPTPYFRWLKSGKSLTMGGRMSVIAGG---SLMIESTMASDEANYTCQAVNNVGSVHMA 555 Query: 997 ANLTIV 1002 L ++ Sbjct: 556 IYLEVI 561 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 9/61 (14%) Query: 1865 ECRIEPYPDPNMRVEWYFNGKVL--QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAI 1922 EC + P+P ++ WY N + L G ND L I TVYG+D+G Y C A Sbjct: 585 ECDVTGEPEP--KITWYQNAQSLGQPKGRISIRDND-----LVIATVYGQDNGVYQCVAD 637 Query: 1923 N 1923 N Sbjct: 638 N 638 Score = 34.3 bits (75), Expect = 2.5 Identities = 40/178 (22%), Positives = 74/178 (41%), Gaps = 18/178 (10%) Query: 3850 ECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN- 3908 EC V + +PK I WY+N + L ++ D V I VY +D+G Y C A N Sbjct: 585 ECDVTGEPEPK--ITWYQNAQSLGQPKGRISIRDNDLV---IATVYGQDNGVYQCVADNG 639 Query: 3909 --------DFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLT 3960 +F F+ T + PDIIL P + + ++ Y ++ LT Sbjct: 640 RELVQSSAEFYAGFSVPTFN-PGTPDIILYPGTPLQITCEVSAIPYPRDVQWYHDDIPLT 698 Query: 3961 EDDLYDVDKKQPPRFVTQIQ--SQTSLVEMETTKFECQLA-PVGDPNMKVEWFFNGKP 4015 Y + + +++ S+T++ ++ +++C + G ++ + G P Sbjct: 699 GGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVYVRGPP 756 Score = 34.3 bits (75), Expect = 2.5 Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 6/101 (5%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS--GHRYRT 1895 V++ +PR + P + EGQ HY C + P + W +GK L S G Sbjct: 840 VSIVVSPRITPFMWAP--VDEGQREHYTCVVAEGDMP-CNITWLRDGKPLYSIPGDLEIM 896 Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 ++ F ++L I V G YTC N G A S +L V Sbjct: 897 TSQF-ISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQLIV 936 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 4/97 (4%) Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-TIGHRFRPIH 1497 S+ + PR P V EGQ H+ C + D + W ++G+P+ +I + Sbjct: 841 SIVVSPRIT--PFMWAPVDEGQREHYTCVVAE-GDMPCNITWLRDGKPLYSIPGDLEIMT 897 Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 +L I ++ G+YTC N G S +L Sbjct: 898 SQFISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQL 934 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 6/96 (6%) Query: 1432 KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH 1491 K ++ S PR + ++ +I G+ +C + W K+G+ +T+G Sbjct: 462 KLVVVPSSSPFAPRMTSLVHNL-TLIAGETAVLQCTAAGSPTPYFR--WLKSGKSLTMGG 518 Query: 1492 RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527 R I +L I +A D YTC+AVN VG+ Sbjct: 519 RMSVIAGG---SLMIESTMASDEANYTCQAVNNVGS 551 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 7/93 (7%) Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE--- 2177 L G C V I P + W+H+ + GH Y T G L + Sbjct: 667 LYPGTPLQITCEVSAIPYPR-DVQWYHDDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAV 725 Query: 2178 ---DSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207 DSG Y C A+N G A + V G NI Sbjct: 726 SMADSGEYKCVASNAAGSAEQVIKVYVRGPPNI 758 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 5/82 (6%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P+ + + + T+ E +C P R W ++GK L G R + SL Sbjct: 474 PRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFR--WLKSGKSLTMGGRMSVIAGG---SL 528 Query: 3890 DILYVYAEDSGEYICRAVNDFG 3911 I A D Y C+AVN+ G Sbjct: 529 MIESTMASDEANYTCQAVNNVG 550 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 3/63 (4%) Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999 +P+ KI WY N + L Q D V + VY +D+G+Y C A N R +S+ Sbjct: 591 EPEPKITWYQNAQSLGQPKGRISIRDNDLV---IATVYGQDNGVYQCVADNGRELVQSSA 647 Query: 3000 TVY 3002 Y Sbjct: 648 EFY 650 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 10/100 (10%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753 PP T + ++ +G + CR + G P I W +G+ R N Sbjct: 755 PPNIT-SFRSSVTGVQGDTISLPCRAK--GFPPPVITWSRSGQTIPYDRRQSIDNG---- 807 Query: 3754 ALDIDYIYARDAGEYTCRATNKWG---SATTTAKITCSAK 3790 L I + D+G+YTC A N G S T T I S + Sbjct: 808 TLLIGNVQKSDSGKYTCTAVNTAGERDSVTMTVSIVVSPR 847 Score = 33.1 bits (72), Expect = 5.7 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 7/96 (7%) Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY-----KSTHDFSYVS-LDI 2835 +I+ G + C V P ++W+ ++ PL G Y T S +S L Sbjct: 664 DIILYPGTPLQITCEVSAIPYPR-DVQWYHDDIPLTGGHDYIITAMPGTKRSSRLSKLSR 722 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871 T DSG Y C A+N+ GSA + G NI Sbjct: 723 TAVSMADSGEYKCVASNAAGSAEQVIKVYVRGPPNI 758 Score = 32.7 bits (71), Expect = 7.5 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 5/61 (8%) Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370 +P+ K+ W+ N + L + D +VI + Y +++G Y+CVA N GR+ ++ Sbjct: 591 EPEPKITWYQNAQSLGQPKGRISIRDNDLVIATV---YGQDNGVYQCVADN--GRELVQS 645 Query: 3371 N 3371 + Sbjct: 646 S 646 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 5/81 (6%) Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031 P F + + Q + V EC + G+P K+ W+ N + L I D V Sbjct: 563 PITFKERPKPQAAQVGFPRKNMECDVT--GEPEPKITWYQNAQSLGQPKGRISIRDNDLV 620 Query: 4032 AMNFGWVYPEDSGEYLCRATN 4052 VY +D+G Y C A N Sbjct: 621 IAT---VYGQDNGVYQCVADN 638 Score = 32.3 bits (70), Expect = 9.9 Identities = 27/104 (25%), Positives = 39/104 (37%), Gaps = 7/104 (6%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTG------SRVKTIND 3611 P F D+IL + C + + V+W+H+ PL G + T Sbjct: 656 PTFNPGTPDIILYPGTPLQITCEVSAI-PYPRDVQWYHDDIPLTGGHDYIITAMPGTKRS 714 Query: 3612 FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI 3655 L V D+G Y C A+N G A K+ V+G I Sbjct: 715 SRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVYVRGPPNI 758 Score = 32.3 bits (70), Expect = 9.9 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 6/84 (7%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P +T+ S +GD CR + P +T W +GQ I + R + D G Sbjct: 755 PPNITSFRSSVTGVQGDTISLPCRAKGFPPPVIT--WSRSGQTIP--YDRRQSIDNG--T 808 Query: 2169 LDILYTYAEDSGTYMCKATNKLGE 2192 L I DSG Y C A N GE Sbjct: 809 LLIGNVQKSDSGKYTCTAVNTAGE 832 >SB_40832| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1496 Score = 88.2 bits (209), Expect = 1e-16 Identities = 85/361 (23%), Positives = 144/361 (39%), Gaps = 33/361 (9%) Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 L++R V DS + +A N G A S + V + ++ N Sbjct: 352 LVLRNVMSSDSGNYTCIASNVVGRASASTMVNVTDPIMPSIARATSDHIATQPESANQDI 411 Query: 4528 GQLVRLDT--------KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579 G+ + L T TG V W + + + + ++ GT +L IL P Sbjct: 412 GKSIVLLTGSSLVLHCNATGHPQPVVTWRRGSQPISGLADHTLI---GT-SLRILNLEPA 467 Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQ 4638 D +Y C A N G+A E V + + +T+ N ++ P+ + + Sbjct: 468 DMEEYTCTASNVGGKAAASTELTVKALSKPNIKTVRTRINNVRRDVTVPIGTTLTTIQNS 527 Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698 + +C G P P + W+K + I P ++ + T+ L I + P DEG Y C A Sbjct: 528 TVVITCPTEGFPKPIISWFKDGEPITPDLKYEANCTS----LIIRDIQPGDEGSYTCTAV 583 Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPA---LTPLRD---------IVVYEGQPAQFKTQITS 4746 N G + VT+P N+ +T +R+ + + G + ++T Sbjct: 584 NPMGTDVNNMSITVTKPPVIINVKGSFEVTDIRELLSITTGAIVTIPRGVTITIRCEVTG 643 Query: 4747 KIKPTIQWLR--EGALIPE--TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802 K +P I W R EG+ + TP + +H ++ L I T + D + C AT AG+ Sbjct: 644 KPEPNITWYRIPEGSQRWQLITPLDRYMHLRSDMSLAIDRTAQVDAAQYVCVATNIAGRD 703 Query: 4803 E 4803 E Sbjct: 704 E 704 Score = 83.8 bits (198), Expect = 3e-15 Identities = 72/264 (27%), Positives = 107/264 (40%), Gaps = 36/264 (13%) Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381 TL +R + +DSG YT A N G S + V P++ T +R Sbjct: 12 TLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKP------------TIERPVAP 59 Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441 R +I +P ++ + V G DC TG P P + W + R++ ++ Sbjct: 60 R-DIPLGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMA- 117 Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK--EQVVAPKFVERFST 499 GN +L+I V S GV TC A N GE + + V++ ++ P ST Sbjct: 118 ---PGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRISRPTIGSTKST 174 Query: 500 LNVR-------------EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546 N+ EG V + A G P P + W KDG+ + P + Sbjct: 175 DNMNPVSISVGSDVTAIEGVTVSIECNATGVPRPEVFWSKDGLRLYPGEYPVLEN----K 230 Query: 547 TLDIPRAKASDAAWYQCTAQNVAG 570 TL I AK D+ +Y CTAQ+ G Sbjct: 231 TLIITNAKVDDSGYYTCTAQSSIG 254 Score = 79.0 bits (186), Expect = 9e-14 Identities = 82/319 (25%), Positives = 132/319 (41%), Gaps = 40/319 (12%) Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338 EG + +G PRP V W K+G RL ++ ++ + TL + N + DSG+YT Sbjct: 192 EGVTVSIECNATGVPRPEVFWSKDGLRLY-PGEYPVL---ENKTLIITNAKVDDSGYYTC 247 Query: 339 LAENPNGCIVTSGYLAVESPTESYVQD--QRSQYITDTQQ----RETEERIEISEKALAP 392 A++ G S + + +S + +Y + + T +++E S+ + P Sbjct: 248 TAQSSIGKDSQSSVVEILRDKQSRLVFGVMSLKYSFSAAEVPIIQRTTDKVEKSD--MKP 305 Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452 V++ G +C G P P++ W N ++ G L++ Sbjct: 306 VDVRIGGQVTSLSGVDITLNCSARGLPPPDIEWM----------NGGKMITVQGPR-LVL 354 Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK-EQVVAPKFVERFST------------ 499 NV SDSG TC+A N G + +NV + +A + +T Sbjct: 355 RNVMSSDSGNYTCIASNVVGRASASTMVNVTDPIMPSIARATSDHIATQPESANQDIGKS 414 Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559 + + G +VL+ A G P P +TW++ PI L HT G S L I + +D Sbjct: 415 IVLLTGSSLVLHCNATGHPQPVVTWRRGSQPI---SGLADHTLIGTS-LRILNLEPADME 470 Query: 560 WYQCTAQNVAGSTATRARL 578 Y CTA NV G A L Sbjct: 471 EYTCTASNVGGKAAASTEL 489 Score = 78.2 bits (184), Expect = 2e-13 Identities = 77/284 (27%), Positives = 114/284 (40%), Gaps = 28/284 (9%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P P++ W R + PI D HT S+ I+ + D + A N GG A S Sbjct: 431 GHPQPVVTWRRGSQPISGLAD---HTLIGTSLRIL-NLEPADMEEYTCTASNVGGKAAAS 486 Query: 4496 ANLVVEE------KRRQGRGGIVPPSFTL-TAQNVNVTSGQLVRLDTKVTG-TKPIDVYW 4547 L V+ K + R V T+ + V + G KPI + W Sbjct: 487 TELTVKALSKPNIKTVRTRINNVRRDVTVPIGTTLTTIQNSTVVITCPTEGFPKPI-ISW 545 Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607 K+G+ + PD++ E +L+I + P D G Y C A+N G + V+ P Sbjct: 546 FKDGEPITPDLK----YEANCTSLIIRDIQPGDEGSYTCTAVNPMGTDVNNMSITVTKPP 601 Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVA--EGQAIEFSCKIVGKPLPTVQWYK---GD-- 4660 K + + E++ IV G I C++ GKP P + WY+ G Sbjct: 602 VIINVKGSFEVTDI-RELLSITTGAIVTIPRGVTITIRCEVTGKPEPNITWYRIPEGSQR 660 Query: 4661 -KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 +LI P + R+ + +L I D Y CVA N AGR Sbjct: 661 WQLITPLDRYMHLRS--DMSLAIDRTAQVDAAQYVCVATNIAGR 702 Score = 74.1 bits (174), Expect = 2e-12 Identities = 65/265 (24%), Positives = 105/265 (39%), Gaps = 21/265 (7%) Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRRQGRGGIVP---------PSFT 4517 L++R+ DS + A N G S+ + V+E + + P P+ Sbjct: 13 LVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAPRDIPLGDGSPTIA 72 Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577 A N V +G + +D TG + W K+G+++ I G +LLI + Sbjct: 73 RIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGREL---IGAGSYMAPGNGSLLIQQVA 129 Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP---QTKAA-NAPPEIIEPLKDKI 4633 G + C A N GE + V P +P TK+ N P I D Sbjct: 130 ASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRISRPTIGSTKSTDNMNPVSISVGSDVT 189 Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 EG + C G P P V W K + P +Y + TL I+ A +D G Y Sbjct: 190 AIEGVTVSIECNATGVPRPEVFWSKDGLRLYPGEY----PVLENKTLIITNAKVDDSGYY 245 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQA 4718 C A +S G+ + ++ +++ + Q+ Sbjct: 246 TCTAQSSIGKDSQSSVVEILRDKQS 270 Score = 72.9 bits (171), Expect = 6e-12 Identities = 62/257 (24%), Positives = 104/257 (40%), Gaps = 28/257 (10%) Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP----QTKAANAPPEI 4625 TL++ A P DSG+Y C A NS G+ ++ V P+ +P + P I Sbjct: 12 TLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAPRDIPLGDGSPTI 71 Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISE 4684 + V G + C G P P++ W K G +LI Y + L I + Sbjct: 72 ARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMAPGNGS----LLIQQ 127 Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP-------------DQADNLP--ALTPLRD 4729 G + C A N G +V++ ++V P DN+ +++ D Sbjct: 128 VAASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRISRPTIGSTKSTDNMNPVSISVGSD 187 Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789 + EG + T +P + W ++G + P + E N L+I N +D+G Sbjct: 188 VTAIEGVTVSIECNATGVPRPEVFWSKDGLRL--YPGEYPVLE--NKTLIITNAKVDDSG 243 Query: 4790 TFTCRATTAAGQVETSA 4806 +TC A ++ G+ S+ Sbjct: 244 YYTCTAQSSIGKDSQSS 260 Score = 72.9 bits (171), Expect = 6e-12 Identities = 112/476 (23%), Positives = 170/476 (35%), Gaps = 69/476 (14%) Query: 4384 STETTEIEHKAQTQERVV---EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLP 4440 S++ IE T ER V + P+ P I + V + + G P P Sbjct: 40 SSQVKVIEPSKPTIERPVAPRDIPLGDGSPTI-ARIADNATVLTGSRLTIDCVATGVPKP 98 Query: 4441 LIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500 I W ++ + + + L+I+QV VF A N G S+N+ V Sbjct: 99 SIIWRKDGRELIGAGSYMA---PGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRV 155 Query: 4501 EEK--RRQGRGGI--------VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKN 4550 + R R I + P +V G V ++ TG +V+W K+ Sbjct: 156 VDPVLPRISRPTIGSTKSTDNMNPVSISVGSDVTAIEGVTVSIECNATGVPRPEVFWSKD 215 Query: 4551 GKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG--------EARCDAEC- 4601 G ++ P +LE TL+I A DSG Y C A +S G E D + Sbjct: 216 GLRLYPG-EYPVLENK---TLIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDKQSR 271 Query: 4602 ----VVSLP---ATKDKPKPQTKAANAPPEIIEPLKDKIVAE-----GQAIEFSCKIVGK 4649 V+SL + + P Q ++P+ +I + G I +C G Sbjct: 272 LVFGVMSLKYSFSAAEVPIIQRTTDKVEKSDMKPVDVRIGGQVTSLSGVDITLNCSARGL 331 Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709 P P ++W G K+I T L + D G+Y C+A N GR + + Sbjct: 332 PPPDIEWMNGGKMI----------TVQGPRLVLRNVMSSDSGNYTCIASNVVGRASASTM 381 Query: 4710 LKVTQP----------DQADNLPALTPL---RDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756 + VT P D P + IV+ G T +P + W R Sbjct: 382 VNVTDPIMPSIARATSDHIATQPESANQDIGKSIVLLTGSSLVLHCNATGHPQPVVTWRR 441 Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812 I D +I L I N D +TC A+ G+ S +L VK+ Sbjct: 442 GSQPISGLADHTLI----GTSLRILNLEPADMEEYTCTASNVGGKAAASTELTVKA 493 Score = 72.9 bits (171), Expect = 6e-12 Identities = 79/304 (25%), Positives = 113/304 (37%), Gaps = 46/304 (15%) Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339 G D G P P + W NG ++I ++ +RN SDSG+YT + Sbjct: 319 GVDITLNCSARGLPPPDIEWM-NGGKMITVQGPRLV---------LRNVMSSDSGNYTCI 368 Query: 340 AENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ 399 A N G S + V P + S +I TQ + I S L Sbjct: 369 ASNVVGRASASTMVNVTDPIMPSIARATSDHIA-TQPESANQDIGKSIVLLT-------- 419 Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 G C TG P P VTW + I +H ++ +L I N+ +D Sbjct: 420 ------GSSLVLHCNATGHPQPVVTWRRGSQPISGLADHTLI-----GTSLRILNLEPAD 468 Query: 460 SGVVTCVARNKSGETAFQCRLNV--IEKEQVVAPKF----------VERFSTLNVREGEP 507 TC A N G+ A L V + K + + V +TL + Sbjct: 469 MEEYTCTASNVGGKAAASTELTVKALSKPNIKTVRTRINNVRRDVTVPIGTTLTTIQNST 528 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 VV+ G P P I+W KDG PI P+ + + ++L I + D Y CTA N Sbjct: 529 VVITCPTEGFPKPIISWFKDGEPITPD----LKYEANCTSLIIRDIQPGDEGSYTCTAVN 584 Query: 568 VAGS 571 G+ Sbjct: 585 PMGT 588 Score = 67.7 bits (158), Expect = 2e-10 Identities = 138/573 (24%), Positives = 228/573 (39%), Gaps = 112/573 (19%) Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028 L I + V D+G+YTC A ++IG+ + S+ + I+ K +S+ G+ ++Y A+ Sbjct: 232 LIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDK----QSRLVFGVMSLKYSFSAAE 287 Query: 1029 YS--KRTEEEV-KITQKP---RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFN 1082 +RT ++V K KP R G + + + + + AR P D +EW Sbjct: 288 VPIIQRTTDKVEKSDMKPVDVRIGGQVTSLSGV--DITLNCSARGLPPPD----IEWMNG 341 Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142 GK IT L + +V + DSG YT +A N G A SAS V I Sbjct: 342 GKMITVQG----------PRLVLRNVMSSDSGNYTCIASNVVGRA--SASTMVNVTDPI- 388 Query: 1143 TSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLE 1202 SI R + HI +P ++I KS + G ++ L C Sbjct: 389 MPSIARATSD---HIA----TQPESANQDIGKSIVLLT-----------GSSLVLHC--N 428 Query: 1203 PMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLG--S 1260 G P V W + ++ G T +L I++ AD EYT A N G + Sbjct: 429 ATGHPQPVVTWRRGSQPIS-GLADHTLIG---TSLRILNLEPADMEEYTCTASNVGGKAA 484 Query: 1261 AHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNI 1320 A T V+ + + +I T R VR D+TV + Sbjct: 485 ASTELTVKALSKPNIKT----------------VRTRINNVRRDVTVPIGT-------TL 521 Query: 1321 ETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380 T++ + V + C + G + WF +G+PI + YE + +L + + P D Sbjct: 522 TTIQNSTVVITCPTE--GFPKPIISWFKDGEPITPDLK----YEANCTSLIIRDIQPGDE 575 Query: 1381 GVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESV 1440 G YTC A N +G V + ++ + K +I+ + ++ TDI + Sbjct: 576 GSYTCTAVNPMGTDVNNMSI-TVTKPPVIINVK--------------GSFEVTDIRELLS 620 Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG 1500 VT P+ G + C++ + N + W++ + P+ + Sbjct: 621 ITTGAIVTIPR-------GVTITIRCEVTGKPEPN--ITWYRIPEGSQRWQLITPLDRYM 671 Query: 1501 YVALDI---IDLIAE-DSGIYTCRAVNLVGTDE 1529 ++ D+ ID A+ D+ Y C A N+ G DE Sbjct: 672 HLRSDMSLAIDRTAQVDAAQYVCVATNIAGRDE 704 Score = 66.9 bits (156), Expect = 4e-10 Identities = 74/313 (23%), Positives = 121/313 (38%), Gaps = 47/313 (15%) Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336 L G+ +G+P+P VTW + Q + H +I T +LR+ N + +D Y Sbjct: 417 LLTGSSLVLHCNATGHPQPVVTWRRGSQPISGLADHTLIGT----SLRILNLEPADMEEY 472 Query: 337 TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396 T A N G S L V++ ++ ++ R++ I + ++ T V Sbjct: 473 TCTASNVGGKAAASTELTVKALSKPNIKTVRTR-INNVRRDVT---------------VP 516 Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456 + + C G P P ++WF + I D + E+ +L+I ++ Sbjct: 517 IGTTLTTIQNSTVVITCPTEGFPKPIISWFKDGEPITPDLKY-----EANCTSLIIRDIQ 571 Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE------------ 504 D G TC A N G + V + ++ K F ++RE Sbjct: 572 PGDEGSYTCTAVNPMGTDVNNMSITVTKPPVIINVK--GSFEVTDIRELLSITTGAIVTI 629 Query: 505 --GEPVVLNARAVGTPTPRITWQK--DGVP---IIPNPELRIHTDGGASTLDIPRAKASD 557 G + + G P P ITW + +G +I + +H S L I R D Sbjct: 630 PRGVTITIRCEVTGKPEPNITWYRIPEGSQRWQLITPLDRYMHLRSDMS-LAIDRTAQVD 688 Query: 558 AAWYQCTAQNVAG 570 AA Y C A N+AG Sbjct: 689 AAQYVCVATNIAG 701 Score = 64.5 bits (150), Expect = 2e-09 Identities = 60/231 (25%), Positives = 96/231 (41%), Gaps = 22/231 (9%) Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316 D LG SP IA+ N+ + G+ +G P+P + W K+G+ LI + + Sbjct: 61 DIPLGDGSPT-IARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSY---M 116 Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376 + +L ++ S G +T A NP G S + V P + I T+ Sbjct: 117 APGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRIS---RPTIGSTKS 173 Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436 + + IS V D EG +C TG P PEV W + ++ Y Sbjct: 174 TDNMNPVSIS----------VGSDVTAIEGVTVSIECNATGVPRPEVFWSKDGLRL---Y 220 Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487 + V E N L+ITN + DSG TC A++ G+ + + ++ +Q Sbjct: 221 PGEYPVLE--NKTLIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDKQ 269 Score = 63.3 bits (147), Expect = 5e-09 Identities = 144/607 (23%), Positives = 222/607 (36%), Gaps = 93/607 (15%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P I W K+G L + G +L I + G++TC ATN +GE +++ Sbjct: 96 PKPSIIWRKDGRELIGAGSYMAP---GNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSN 152 Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791 I++ D +L P IG+ V IS +++ EG + Sbjct: 153 IRVVDP--VLPRISRPT----IGS----------TKSTDNMNPVSISVGSDVTAIEGVTV 196 Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851 ECN + P ++ W + L G Y + + + IT+ +DSG YTC A Sbjct: 197 SIECNA--TGVPRPEVFWSKDGLRLYPG-EYPVLENKTLI---ITNAKVDDSGYYTCTAQ 250 Query: 2852 NSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKP 2911 +S G + S + DK ++ G L+ A E + + V ++ Sbjct: 251 SSIGKDSQSSVVEILRDKQ----SRLVFGVMSLKYSFSAAEVPIIQRTTDKVEKSDMKPV 306 Query: 2912 EWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLE-QGSRFKLTSDFGFVT 2970 + + I + + G + L PD IEW GK++ QG R Sbjct: 307 D--VRIGGQVTSLSGVDITLNCSARGLPPPD--IEWMNGGKMITVQGPR----------- 351 Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLED 3030 L L +V DSG YTC A N G A S+ V T D ++ D Sbjct: 352 LVLRNVMSSDSGNYTCIASNVVGRASASTMVNVT--DPIMPSIARATS-----------D 398 Query: 3031 SLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090 + +P + + D G+ T + H A TG V+ W + Sbjct: 399 HIATQP-ESANQDIGKSIVLLT--------GSSLVLHCNA----TGHPQPVVTWRRGSQP 445 Query: 3091 IE--ASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK 3148 I A H + G L IL + D Y+C A+N G+A S +L SK Sbjct: 446 ISGLADHTL-----IG-TSLRILNLEPADMEEYTCTASNVGGKAAASTELTVKALSKPNI 499 Query: 3149 PRFTTHIQNIE---------GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199 T I N+ L Q++ T P I W+ +G+P+ + + Sbjct: 500 KTVRTRINNVRRDVTVPIGTTLTTIQNSTVVITCPTEGFPKPIISWFKDGEPITPDLKYE 559 Query: 3200 TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAK 3259 + ++ DI Q D G Y C A N G D +I K V + + Sbjct: 560 -ANCTSLIIRDI---QPGDEGSYTCTAVNPMGTDVNNMSIT-VTKPPVIINVKGSFEVTD 614 Query: 3260 IRELESL 3266 IREL S+ Sbjct: 615 IRELLSI 621 Score = 62.9 bits (146), Expect = 6e-09 Identities = 52/221 (23%), Positives = 97/221 (43%), Gaps = 15/221 (6%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P++ + + + G+ + + G+P+P VTW+ ++ S + +T TL + Sbjct: 1158 PRVDKLDSLATVVRGSTLRIRCAAYGSPKPSVTWY-----VVGSERKADLTVLPDGTLEL 1212 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE- 384 N D G+YT +A N G S + V P S + + + I + +R Sbjct: 1213 ENVDFMDEGNYTCVARNAYGVTSRSTNVTVLVPP-SILDNFFADAILVQHSKLLHKRYSS 1271 Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444 I+ ++ Q ++ V G C V+GRP P + W N +I +D + +++V Sbjct: 1272 ITRLSIRRQQIRQAA---VERGANLIIGCPVSGRPLPAIQWLRNGLKISND-SRQVIV-- 1325 Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485 +MI ++ L +G C +N +GE L+V E+ Sbjct: 1326 --GGVIMIRDIQLQHAGEYFCYVKNTAGEDGGGVDLSVRER 1364 Score = 59.3 bits (137), Expect = 8e-08 Identities = 145/656 (22%), Positives = 255/656 (38%), Gaps = 118/656 (17%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 P + I +I D ++ G + V P + W +G++L Y + Sbjct: 63 PLGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPS--IIWRKDGRELIGAGSYMAPGN 120 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK 3396 ++I + + G + C ATN +G DS +N++ ++D LPR Sbjct: 121 GSLLIQQVAASHH---GVFTCTATNPVGEDSVSSNIR-------VVDPVLPR-------- 162 Query: 3397 LQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456 + R S + PV S++ + EG E T P +V W Sbjct: 163 -------ISRPTIGSTKSTDNMNPVSISVGSDVTAI-EGVTVSIECNATGVPRP--EVFW 212 Query: 3457 YWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV-QGK 3515 +G L G + L I+ +DSG Y C A ++ G+ ++ +++ + K Sbjct: 213 SKDGLRLYPGE----YPVLENKTLIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDK 268 Query: 3516 RNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSA 3575 ++ ++ + + ++ ++ + V+ + T+ S + ++ N SA Sbjct: 269 QSRLVFGVMSLKYSFSAAEVPIIQRTTDKVEKSDMKPVDVRIGGQVTSLSGVDITLNCSA 328 Query: 3576 HFECRLIPVNDSSMRVEWFHNGKPL-LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634 R +P D +EW + GK + + G R L + V D+G YTC A Sbjct: 329 ----RGLPPPD----IEWMNGGKMITVQGPR-----------LVLRNVMSSDSGNYTCIA 369 Query: 3635 TNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNP 3694 +N G A+ S + V +P +PS ++ ++ I E+ ++ Sbjct: 370 SNVVGRASASTMVNVT-------DPIMPSIARATSDHIATQPESANQ------------- 409 Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 +I +I + G + C G P + W +P + G HTL Sbjct: 410 -----DIGKSIVLLTGSSLVLHCNA--TGHPQPVVTWRRGSQPIS-GLADHTLIGTSLRI 461 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814 L+++ D EYTC A+N G A + ++T A +S IK + R Sbjct: 462 LNLE---PADMEEYTCTASNVGGKAAASTELTVKA-------------LSKPNIKTV-RT 504 Query: 3815 RISDAPKEE--PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872 RI++ ++ PI +T +T I++ TV C E PK I W+++G+ + Sbjct: 505 RINNVRRDVTVPIGTT----LTTIQNSTVV------ITCPTEGF--PKPIISWFKDGEPI 552 Query: 3873 PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928 +Y + SL I + D G Y C AVN G D +I+ K P II Sbjct: 553 TPDLKY----EANCTSLIIRDIQPGDEGSYTCTAVNPMGTDVNNMSITVTKPPVII 604 Score = 56.0 bits (129), Expect = 7e-07 Identities = 104/435 (23%), Positives = 174/435 (40%), Gaps = 72/435 (16%) Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEK-TRHIEESK 1161 L I + + +DSG YT A+++ G+ S S VE + + + K + E Sbjct: 232 LIITNAKVDDSGYYTCTAQSSIGKD--SQSSVVEILRDKQSRLVFGVMSLKYSFSAAEVP 289 Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221 ++ E S KPV V+ +S G +I L C G P +EW + G+ +T Sbjct: 290 IIQRTTDKVEKSDMKPVDVRIGGQVTSLS-GVDITLNCSAR--GLPPPDIEWMNGGKMIT 346 Query: 1222 V-GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280 V G R L + + S+D+G YT A N +G A S +V V +D + + Sbjct: 347 VQGPR-----------LVLRNVMSSDSGNYTCIASNVVGRASASTMVNV---TDPIMPSI 392 Query: 1281 NEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQ 1340 + I A + + +DI +I + G+++ L C G Sbjct: 393 ARATSDHI------ATQPESANQDIG-----------KSIVLLTGSSLVLHCNA--TGHP 433 Query: 1341 TMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400 V W +PI + +L +L++ P D YTC A+N G+A S Sbjct: 434 QPVVTWRRGSQPISG----LADHTLIGTSLRILNLEPADMEEYTCTASNVGGKAAAST-- 487 Query: 1401 RVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQ 1460 +L +++ ++ ++ + R T I ++T I+ Sbjct: 488 ------ELTVKALSKPNIKTVRTRINNVRRDVTVPIGTTLT--------------TIQNS 527 Query: 1461 HVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCR 1520 V C E + WFK+G+P+T ++ + +L I D+ D G YTC Sbjct: 528 TVVITCPTEGFPKPI--ISWFKDGEPITPDLKY----EANCTSLIIRDIQPGDEGSYTCT 581 Query: 1521 AVNLVGTDEVSCRLT 1535 AVN +GTD + +T Sbjct: 582 AVNPMGTDVNNMSIT 596 Score = 53.6 bits (123), Expect = 4e-06 Identities = 162/689 (23%), Positives = 251/689 (36%), Gaps = 127/689 (18%) Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLECVDKSKG--QKPRFTTHIQNIEG----------- 3160 + DSG Y+C A N G+ IS +++ ++ SK ++P I +G Sbjct: 19 RPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAPRDIPLGDGSPTIARIADNA 78 Query: 3161 -LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219 + G +C V P I W +G+ + + + ++ +A + + Sbjct: 79 TVLTGSRLTIDCVATGVPKPS--IIWRKDGRELIGAGSYMAPGNGSLLIQQVAASHH--- 133 Query: 3220 GEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA 3279 G + C A N GED + I ++ + P R G+ T ST + Sbjct: 134 GVFTCTATNPVGEDSVSSNIRV-------VDPVLP------RISRPTIGS---TKSTDNM 177 Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339 P I+ DVT +EG + E V P+ V W +G +L G Y + + Sbjct: 178 NPVS-ISVGSDVTA-IEGVTVSIECNATGVPRPE--VFWSKDGLRLYPGE-YPVLENKTL 232 Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQT 3399 +I + ++SG Y C A + +G+DS + ++ + S+L G+ Sbjct: 233 IITNAKV---DDSGYYTCTAQSSIGKDSQSSVVEILRDK----QSRLVFGVMSLKYSFSA 285 Query: 3400 LEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGE-NAHFEARLTPTDDPNLKVEWYW 3458 E +++R VE+ K PV + +L + + AR P D +EW Sbjct: 286 AEVPIIQRTTDKVEKSDMK-PVDVRIGGQVTSLSGVDITLNCSARGLPPPD----IEWMN 340 Query: 3459 NGKSLKA-GSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517 GK + G R L + DSG Y C A N G A +AS V Sbjct: 341 GGKMITVQGPR-----------LVLRNVMSSDSGNYTCIASNVVGRA--SASTMVN---- 383 Query: 3518 IILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHF 3577 + + +P T D IA + S D T S L+L N++ H Sbjct: 384 -VTDPIMPSIARATSDHIAT-QPESANQDI--------GKSIVLLTGSSLVLHCNATGHP 433 Query: 3578 ECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNR 3637 + PV V W +P ++G T+ IL + D YTC A+N Sbjct: 434 Q----PV------VTWRRGSQP-ISGLADHTLIGTSLRILNL---EPADMEEYTCTASNV 479 Query: 3638 HGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRF 3697 G+A S +L VK + +P + +T+ R D Sbjct: 480 GGKAAASTELTVKA----LSKPNI---------------KTVRTRINNVRRD-------V 513 Query: 3698 TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDI 3757 TV I + + V C E G P I WF +G P T + N I DI Sbjct: 514 TVPIGTTLTTIQNSTVVITCPTE--GFPKPIISWFKDGEPI-TPDLKYEANCTSLIIRDI 570 Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKIT 3786 D G YTC A N G+ IT Sbjct: 571 Q---PGDEGSYTCTAVNPMGTDVNNMSIT 596 Score = 53.2 bits (122), Expect = 5e-06 Identities = 133/578 (23%), Positives = 212/578 (36%), Gaps = 95/578 (16%) Query: 1648 GTYTCRAINALGE-AVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV 1706 G +TC A N +GE +V+S I +V + LPR+++ S + Sbjct: 134 GVFTCTATNPVGEDSVSSNIRVV------------DPVLPRISRPTIGSTKSTDNMN--- 178 Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 PV D+ E E G P+ V W ++G+ + + + Sbjct: 179 ----PVSISVGSDVTAIEGVTVSIECNA--TGVPRPEVFWSKDGLRLYPGE-YPVLENKT 231 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLED 1826 + N K +DSG YTC A + +G+ SS + + +L S E Sbjct: 232 LIITNAKV---DDSGYYTCTAQSSIGKDSQSSVVEILRDKQSRLVFGVMSLKYSFSAAEV 288 Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886 + + VE + + P + ++ G G C P P+ +EW GK+ Sbjct: 289 PIIQRTTDKVEKS-DMKPVDV-RIGGQVTSLSGVDITLNCSARGLPPPD--IEWMNGGKM 344 Query: 1887 LQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945 + G R L + V DSG YTC A N +G+A +S +NV I Sbjct: 345 ITVQGPR-----------LVLRNVMSSDSGNYTCIASNVVGRASASTMVNVTDP---IMP 390 Query: 1946 SQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVN 2005 S + + I A Q +S GK I + G + L T Sbjct: 391 SIARATSDHI-----------ATQPES---ANQDIGKSI---VLLTGSSLVLHCNAT--G 431 Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065 P V W +P+ G T +L IL D Y C A+N G+A ++ Sbjct: 432 HPQPVVTWRRGSQPI-SGLADHTLIG---TSLRILNLEPADMEEYTCTASNVGGKAAAST 487 Query: 2066 SVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGD 2125 + V A S + T+ R+ ++ + PI T LT+++N Sbjct: 488 ELTVKALSKPNIKTV-RTRINNVRR----DVTVPIG-----------TTLTTIQN----S 527 Query: 2126 RAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCK 2185 C E P I WF +G+ I +Y + +L I D G+Y C Sbjct: 528 TVVITCPTEGFPKP--IISWFKDGEPITPDLKY----EANCTSLIIRDIQPGDEGSYTCT 581 Query: 2186 ATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL 2223 A N +G VN ++ V +I++ + + IR+L Sbjct: 582 AVNPMGTDVNNMSITVT-KPPVIINVKGSFEVTDIREL 618 Score = 52.0 bits (119), Expect = 1e-05 Identities = 117/461 (25%), Positives = 179/461 (38%), Gaps = 86/461 (18%) Query: 3613 GFVILEIGGVYQR-----DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKS 3667 G+VI + G + R D+G YTC A N G+ +S QVK ++EP P+ Sbjct: 4 GYVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISS--QVK-----VIEPSKPT---- 52 Query: 3668 GTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTM 3727 +E + R +I + D P R I DN V G + DC G P Sbjct: 53 -------IERPVAPR-DIPLGDGSPTIAR----IADNATVLTGSRLTIDC--VATGVPKP 98 Query: 3728 RIDWFHNGRP-FATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786 I W +GR GS + N +L I + A G +TC ATN G + ++ I Sbjct: 99 SIIWRKDGRELIGAGSYMAPGNG----SLLIQQVAASHHGVFTCTATNPVGEDSVSSNIR 154 Query: 3787 CSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846 V++ LP +I G P+ + +T I+ TV Sbjct: 155 -------VVDPVLP------RISRPTIGSTKSTDNMNPVSISVGSDVTAIEGVTVS---- 197 Query: 3847 VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906 EC P+ + W ++G L G Y + + +L I +DSG Y C A Sbjct: 198 --IECNATGV--PRPEVFWSKDGLRLYPG-EYPVLENK---TLIITNAKVDDSGYYTCTA 249 Query: 3907 VNDFGEDFTKATISCKKLPDIILQNQVPRG-MKRSEALTQMEATIKKYTSEVYLTEDDLY 3965 + G+D + + L D Q+++ G M + + E I + T++ + + D+ Sbjct: 250 QSSIGKDSQSSVVEI--LRD--KQSRLVFGVMSLKYSFSAAEVPIIQRTTD-KVEKSDMK 304 Query: 3966 DVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPI 4025 VD R Q+ TSL ++ T C G P +EW GK + + Sbjct: 305 PVD----VRIGGQV---TSLSGVDIT-LNCSAR--GLPPPDIEWMNGGKMI-------TV 347 Query: 4026 YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066 V N V DSG Y C A+N+ G ++ T Sbjct: 348 QGPRLVLRN---VMSSDSGNYTCIASNVVGRASASTMVNVT 385 Score = 50.8 bits (116), Expect = 3e-05 Identities = 45/151 (29%), Positives = 70/151 (46%), Gaps = 20/151 (13%) Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEG 4735 D TL + A P D G Y C A NS G+ +++++KV +P + + P RDI + +G Sbjct: 9 DNGTLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAP-RDIPLGDG 67 Query: 4736 QP-----AQFKTQIT-SKI----------KPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779 P A T +T S++ KP+I W ++G + + + GN + LL Sbjct: 68 SPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSY--MAPGNGS-LL 124 Query: 4780 IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 I G FTC AT G+ S+ + V Sbjct: 125 IQQVAASHHGVFTCTATNPVGEDSVSSNIRV 155 Score = 50.0 bits (114), Expect = 5e-05 Identities = 107/473 (22%), Positives = 179/473 (37%), Gaps = 71/473 (15%) Query: 1099 GYVALD-----IASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEK 1153 GYV D + R DSG YT A N+ G+ +S+ + V S +I R + Sbjct: 4 GYVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSK---PTIERPV--A 58 Query: 1154 TRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEW 1213 R I + P + N V G + ++C G P + W Sbjct: 59 PRDIP-------------LGDGSPTIARIADNAT-VLTGSRLTIDC--VATGVPKPSIIW 102 Query: 1214 FHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273 +GR + +G+ +Y G +L I ++ G +T A N +G S+ +RV+ Sbjct: 103 RKDGREL-IGAG--SYMAPGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVV--- 156 Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333 D V + I + ++ + V D+T +EG V +EC Sbjct: 157 DPVLPRISRPTIGSTKSTDNMNPVSISVGSDVTA---------------IEGVTVSIECN 201 Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393 G V W +G + G P E + + V +DSG YTC A + +G+ Sbjct: 202 A--TGVPRPEVFWSKDGLRLYPGEY--PVLENKTLIITNAKV--DDSGYYTCTAQSSIGK 255 Query: 1394 AVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSI 1453 S + ++ K L S E + TD +++S +KP V + Sbjct: 256 DSQSSVVEILRDKQSRLVFGVMSLKYSFSAAEVPIIQRTTDKVEKS-DMKPVDVRIGGQV 314 Query: 1454 ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTI-GHRFRPIHDFGYVALDIIDLIAE 1512 + + G + C + + +EW G+ +T+ G R L + ++++ Sbjct: 315 TS-LSGVDITLNCSARGLPPPD--IEWMNGGKMITVQGPR-----------LVLRNVMSS 360 Query: 1513 DSGIYTCRAVNLVGTDEVS--CRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563 DSG YTC A N+VG S +T I R+T + + +D K Sbjct: 361 DSGNYTCIASNVVGRASASTMVNVTDPIMPSIARATSDHIATQPESANQDIGK 413 Score = 50.0 bits (114), Expect = 5e-05 Identities = 52/210 (24%), Positives = 80/210 (38%), Gaps = 35/210 (16%) Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 + K P+ K+ V G R C G P P VTW++ + + D + V Sbjct: 1152 ANKFTRPRVDKLDSLATVVRGSTLRIRCAAYGSPKPSVTWYVVGSERKAD----LTVLPD 1207 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE---------- 495 G L + NV D G TCVARN G T+ + V+ ++ F + Sbjct: 1208 G--TLELENVDFMDEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKLL 1265 Query: 496 --RFSTLN-------------VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH 540 R+S++ V G +++ G P P I W ++G+ I N ++ Sbjct: 1266 HKRYSSITRLSIRRQQIRQAAVERGANLIIGCPVSGRPLPAIQWLRNGLK-ISNDSRQVI 1324 Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 G DI A + Y C +N AG Sbjct: 1325 VGGVIMIRDIQLQHAGE---YFCYVKNTAG 1351 Score = 48.8 bits (111), Expect = 1e-04 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 6/65 (9%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 G P P++SW + P+ KY + SL+I+ I PGDEG YTCTA N G + Sbjct: 537 GFPKPIISWFKDGEPITPDLKY------EANCTSLIIRDIQPGDEGSYTCTAVNPMGTDV 590 Query: 157 CSVYI 161 ++ I Sbjct: 591 NNMSI 595 Score = 47.2 bits (107), Expect = 3e-04 Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 18/147 (12%) Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK-----EQVVAPK--------- 492 N L++ +DSG TC A N G+ ++ VIE E+ VAP+ Sbjct: 10 NGTLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAPRDIPLGDGSP 69 Query: 493 FVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551 + R + V G + ++ A G P P I W+KDG +I + G +L I Sbjct: 70 TIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGS---YMAPGNGSLLIQ 126 Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578 + AS + CTA N G + + + Sbjct: 127 QVAASHHGVFTCTATNPVGEDSVSSNI 153 Score = 46.0 bits (104), Expect = 8e-04 Identities = 49/188 (26%), Positives = 70/188 (37%), Gaps = 28/188 (14%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 PR V ++ S ++V T + C A G P V W+ G K T + D Sbjct: 1158 PR-VDKLDSLATVVRGSTLRIRC--AAYGSPKPSVTWYVVGSE--RKADLTVLPDGTLEL 1212 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV----YDSQLPKHMKSIEKIR 4088 N ++ D G Y C A N YG+ + P I+ D+ L +H K + K Sbjct: 1213 ENVDFM---DEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKLLHKRY 1269 Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148 + +Q+ + VE G C V+G P P + WL NG Sbjct: 1270 SSITRLSIRRQQIRQ----------------AAVERGANLIIGCPVSGRPLPAIQWLRNG 1313 Query: 4149 NTIVNGSR 4156 I N SR Sbjct: 1314 LKISNDSR 1321 Score = 43.6 bits (98), Expect = 0.004 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 6/88 (6%) Query: 67 GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126 G+ SP I +I NA G + G P P + W + L+ Y Sbjct: 65 GDGSPTI-ARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMA-----P 118 Query: 127 GDVSLLIKQIGPGDEGEYTCTARNQYGE 154 G+ SLLI+Q+ G +TCTA N GE Sbjct: 119 GNGSLLIQQVAASHHGVFTCTATNPVGE 146 Score = 42.7 bits (96), Expect = 0.007 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P + W+KDG PIT + + SL I ++ D GSYT AVN +G ++ S Sbjct: 539 PKPIISWFKDGEPITPDLK----YEANCTSLIIRDIQPGDEGSYTCTAVNPMGTDVNNMS 594 Query: 860 IRV 862 I V Sbjct: 595 ITV 597 Score = 41.5 bits (93), Expect = 0.016 Identities = 45/170 (26%), Positives = 74/170 (43%), Gaps = 15/170 (8%) Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028 L +++V D G+YTC A NA G + S N+T++ I+ L + L R Sbjct: 1210 LELENVDFMDEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKLLH-KR 1268 Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088 YS T ++ Q+ R +G N I+ R P ++W NG +I++ Sbjct: 1269 YSSITRLSIR-RQQIRQAAVERGANLII---GCPVSGRPLP------AIQWLRNGLKISN 1318 Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 +R Q G V + I ++ + +G Y +N AGE ++V R Sbjct: 1319 DSR-QVI--VGGVIM-IRDIQLQHAGEYFCYVKNTAGEDGGGVDLSVRER 1364 Score = 40.3 bits (90), Expect = 0.037 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 6/84 (7%) Query: 75 EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIK 134 + I K+ G + G+P PVV+W R P+ +++ SL I Sbjct: 409 QDIGKSIVLLTGSSLVLHCNATGHPQPVVTWRRGSQPISGLADHTLI------GTSLRIL 462 Query: 135 QIGPGDEGEYTCTARNQYGEAICS 158 + P D EYTCTA N G+A S Sbjct: 463 NLEPADMEEYTCTASNVGGKAAAS 486 Score = 39.5 bits (88), Expect = 0.065 Identities = 37/162 (22%), Positives = 62/162 (38%), Gaps = 29/162 (17%) Query: 3983 TSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPED 4042 T+L ++ + G P + WF +G+P+ + Y+ ++ + P D Sbjct: 519 TTLTTIQNSTVVITCPTEGFPKPIISWFKDGEPITPDLK----YEANCTSLIIRDIQPGD 574 Query: 4043 SGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVV 4102 G Y C A N G D I T P I+ ++ S++VT + Sbjct: 575 EGSYTCTAVNPMGTDVNNMSITVTKPPVII----------------NVKGSFEVTD---I 615 Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144 E + V++P VT+ C VTG P+P + W Sbjct: 616 RELLSITTGAIVTIPRGVTI------TIRCEVTGKPEPNITW 651 Score = 39.5 bits (88), Expect = 0.065 Identities = 48/205 (23%), Positives = 77/205 (37%), Gaps = 34/205 (16%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V G + C G P P+V WY ++ + ++ D TL + DEG+Y Sbjct: 1169 VVRGSTLRIRCAAYGSPKPSVTWY----VVGSERKADLTVLPDG-TLELENVDFMDEGNY 1223 Query: 4694 KCVAYNSAGRVTVAAKLKV-TQPDQADNL-----------------PALTPL-------R 4728 CVA N+ G + + + V P DN ++T L R Sbjct: 1224 TCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKLLHKRYSSITRLSIRRQQIR 1283 Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788 V G ++ + P IQWLR G I + D + + G V++I + + Sbjct: 1284 QAAVERGANLIIGCPVSGRPLPAIQWLRNGLKI--SNDSRQVIVG--GVIMIRDIQLQHA 1339 Query: 4789 GTFTCRATTAAGQVETSAKLVVKSK 4813 G + C AG+ L V+ + Sbjct: 1340 GEYFCYVKNTAGEDGGGVDLSVRER 1364 Score = 39.1 bits (87), Expect = 0.086 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 + W KDG P+ + + +L I+ + D G YTC A N +G + ++T V Sbjct: 543 ISWFKDGEPITPDLK----YEANCTSLIIRDIQPGDEGSYTCTAVNPMGTDVNNMSIT-V 597 Query: 1003 TKKDII 1008 TK +I Sbjct: 598 TKPPVI 603 Score = 39.1 bits (87), Expect = 0.086 Identities = 42/159 (26%), Positives = 68/159 (42%), Gaps = 15/159 (9%) Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814 L+++ + D G YTC A N +G + + +T I L++ + + K L + Sbjct: 1210 LELENVDFMDEGNYTCVARNAYGVTSRSTNVTVLVPPSI-LDNFFADAILVQHSKLLHK- 1267 Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874 R S + +S + QI+ VE + C V + P I+W RNG + + Sbjct: 1268 RYSSITR----LSIRRQ---QIRQAAVERGANLIIGCPVSGR--PLPAIQWLRNGLKISN 1318 Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913 R V G V + I + + +GEY C N GED Sbjct: 1319 DSRQVIV---GGVIM-IRDIQLQHAGEYFCYVKNTAGED 1353 Score = 38.3 bits (85), Expect = 0.15 Identities = 44/172 (25%), Positives = 71/172 (41%), Gaps = 19/172 (11%) Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494 +G P P+I W+++ PI +PD + T LIIR + D + A N GT Sbjct: 536 EGFPKPIISWFKDGEPI--TPDLKYEANCTS--LIIRDIQPGDEGSYTCTAVNPMGTDVN 591 Query: 4495 SANLVVEEK----RRQGRGGIVPPSFTL---TAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547 + ++ V + +G + L T V + G + + +VTG ++ W Sbjct: 592 NMSITVTKPPVIINVKGSFEVTDIRELLSITTGAIVTIPRGVTITIRCEVTGKPEPNITW 651 Query: 4548 --LKNGKK----VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593 + G + + P R L D +L I D+ +Y CVA N AG Sbjct: 652 YRIPEGSQRWQLITPLDRYMHLRSD--MSLAIDRTAQVDAAQYVCVATNIAG 701 Score = 38.3 bits (85), Expect = 0.15 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 13/124 (10%) Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162 L++ +V D G YT VARNA G S ++TV + SI + ++ SK Sbjct: 1210 LELENVDFMDEGNYTCVARNAYGVTSRSTNVTV-----LVPPSILDNFFADAILVQHSKL 1264 Query: 1163 VEPMY-QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221 + Y I +S + Q V G N+ + C + G P ++W NG ++ Sbjct: 1265 LHKRYSSITRLSIRRQQIRQ-----AAVERGANLIIGCPVS--GRPLPAIQWLRNGLKIS 1317 Query: 1222 VGSR 1225 SR Sbjct: 1318 NDSR 1321 Score = 37.9 bits (84), Expect = 0.20 Identities = 47/217 (21%), Positives = 84/217 (38%), Gaps = 20/217 (9%) Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705 VTA+EG + E G P ++ W K+G + + +L + + + D Sbjct: 188 VTAIEGVTVSIECNA--TGVPRPEVFWSKDGLRLYPGEYPVLENK----TLIITNAKVDD 241 Query: 706 SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQ 765 SG YTC A S+ G +V+ + R R +L+Y + Q E+ Sbjct: 242 SGYYTCTAQSSIGKDSQSSVVEIL-RDKQSRLVFGVMSLKYSFSAAEVPIIQRTTDKVEK 300 Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825 + +P +R G++ + P +EW G+ IT Sbjct: 301 SDMKPVDVR---IGGQVTSLSGVDITLNCSARGLPPPDIEWMNGGKMITVQG-------- 349 Query: 826 GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 L + ++ + D+G+YT A N +G A ++ + V Sbjct: 350 --PRLVLRNVMSSDSGNYTCIASNVVGRASASTMVNV 384 Score = 37.1 bits (82), Expect = 0.35 Identities = 44/182 (24%), Positives = 68/182 (37%), Gaps = 12/182 (6%) Query: 3979 IQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWV 4038 + S + +E T EC G P +V W +G L + + + + + N Sbjct: 184 VGSDVTAIEGVTVSIECNAT--GVPRPEVFWSKDGLRL-YPGEYPVLENKTLIITN---A 237 Query: 4039 YPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTP 4098 +DSG Y C A + G D +V++ S+L + S+ K A + Sbjct: 238 KVDDSGYYTCTAQSSIGKDSQSSVVEILRDK----QSRLVFGVMSL-KYSFSAAEVPIIQ 292 Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI-VNGSRY 4157 + K+ PV V + VT G C G P P + W+ G I V G R Sbjct: 293 RTTDKVEKSDMKPVDVRIGGQVTSLSGVDITLNCSARGLPPPDIEWMNGGKMITVQGPRL 352 Query: 4158 KL 4159 L Sbjct: 353 VL 354 Score = 37.1 bits (82), Expect = 0.35 Identities = 46/212 (21%), Positives = 77/212 (36%), Gaps = 25/212 (11%) Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565 QG P V G +R+ G+ V W G + + D+ + Sbjct: 1150 QGANKFTRPRVDKLDSLATVVRGSTLRIRCAAYGSPKPSVTWYVVGSERKADLT---VLP 1206 Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT-----------KDKPKP 4614 DGT L ++ D G Y CVA N+ G V +P + K Sbjct: 1207 DGTLELENVDF--MDEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKL 1264 Query: 4615 QTKAANAPPEII---EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQ 4670 K ++ + + ++ V G + C + G+PLP +QW + G K+ S+ Sbjct: 1265 LHKRYSSITRLSIRRQQIRQAAVERGANLIIGCPVSGRPLPAIQWLRNGLKISNDSRQVI 1324 Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 + + I + + G+Y C N+AG Sbjct: 1325 VGG-----VIMIRDIQLQHAGEYFCYVKNTAG 1351 Score = 36.3 bits (80), Expect = 0.61 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 22/124 (17%) Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPE 4099 P DSG Y C A N G D + +K V + P +IE+ V P Sbjct: 20 PADSGRYTCTANNSRGKDHISSQVK-------VIEPSKP----TIER--------PVAPR 60 Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 + + P + D TV G C TG PKP ++W +G ++ Y Sbjct: 61 DIPLGDGS---PTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMA 117 Query: 4160 TYDG 4163 +G Sbjct: 118 PGNG 121 Score = 35.5 bits (78), Expect = 1.1 Identities = 38/131 (29%), Positives = 56/131 (42%), Gaps = 8/131 (6%) Query: 2243 RFVTELRGTT-HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301 R VT GTT + T C E P I ++ +G+ + + ++ S Sbjct: 511 RDVTVPIGTTLTTIQNSTVVITCPTEGFPKPI--ISWFKDGEPITP----DLKYEANCTS 564 Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361 L I+ P D G Y+ A+N +G + +S+TVT II+ E + IREL S Sbjct: 565 LIIRDIQPGDEGSYTCTAVNPMGTDVNNMSITVTKPPVIINVKGSFE-VTDIRELLSITT 623 Query: 2362 FKRPEIPEPVT 2372 IP VT Sbjct: 624 GAIVTIPRGVT 634 Score = 35.1 bits (77), Expect = 1.4 Identities = 64/290 (22%), Positives = 112/290 (38%), Gaps = 48/290 (16%) Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDS 1972 DSG YTC A N+ G+ ++ S+ +I S+ +E+ A +D Sbjct: 22 DSGRYTCTANNSRGKD------HISSQVKVIEPSK--PTIER----------PVAPRDIP 63 Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032 P + NA V G + ++ T V P+ + W +GR + + Sbjct: 64 LGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPS--IIWRKDGRELIGAGSYMAP--- 118 Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092 G +L I A G + C ATN VGE +S+++V +D + L Sbjct: 119 GNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRV-------VDPV----------LP 161 Query: 2093 KYERPK-PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151 + RP + PV ++ + + + EG EC + P + W +G + Sbjct: 162 RISRPTIGSTKSTDNMNPVSISVGSDVTAI-EGVTVSIECNATGV--PRPEVFWSKDGLR 218 Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + G Y + L I +DSG Y C A + +G+ + +++ Sbjct: 219 LYPG-EYPVLEN---KTLIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEI 264 Score = 35.1 bits (77), Expect = 1.4 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 945 WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 W KDGR + + ++ G +L I+ V G +TC A N +G+ + S+N+ +V Sbjct: 102 WRKDGRELIGAG---SYMAPGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVV 156 Score = 35.1 bits (77), Expect = 1.4 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 4/54 (7%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664 + W+ + +P+ ++ E N + DI P D G+YTC A+N +G V + Sbjct: 543 ISWFKDGEPITPDLKY-EANCTSLIIRDIQ---PGDEGSYTCTAVNPMGTDVNN 592 Score = 34.3 bits (75), Expect = 2.5 Identities = 49/202 (24%), Positives = 81/202 (40%), Gaps = 16/202 (7%) Query: 1646 DSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDE 1705 D G YTC A NA G S V SI + L + ++L ++R+S+ Sbjct: 1219 DEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKL----LHKRYSS--- 1271 Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765 IT+ + ++ + A + A+ G P ++WLRNG+ I +R + Sbjct: 1272 -ITRLSIRRQQIR--QAAVERGANLIIGCPVSGRPLPAIQWLRNGLKISNDSRQVIV--- 1325 Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQ--LESQHESALQKIQQ 1823 G V + ++ + + +G Y C N GE L V+ + Q + E + Q Sbjct: 1326 GGVIM-IRDIQLQHAGEYFCYVKNTAGEDGGGVDLSVRERIVGQWYISPWTEYLATRFVQ 1384 Query: 1824 LEDSSRYQRREDVEVAVNQAPR 1845 L+ R + VE PR Sbjct: 1385 LKSGFTQIRAQTVEPGFYDVPR 1406 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550 P+ + S V G + + A G+P P +TW G +L + DG TL++ Sbjct: 1158 PRVDKLDSLATVVRGSTLRIRCAAYGSPKPSVTWYVVGSE--RKADLTVLPDG---TLEL 1212 Query: 551 PRAKASDAAWYQCTAQNVAGSTA 573 D Y C A+N G T+ Sbjct: 1213 ENVDFMDEGNYTCVARNAYGVTS 1235 Score = 33.9 bits (74), Expect = 3.2 Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 23/163 (14%) Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676 LE+ V D G YTC A N +G + S + V ++ P + +F + +Q Sbjct: 1210 LELENVDFMDEGNYTCVARNAYGVTSRSTNVTV------LVPPSILDNFFADAILVQH-S 1262 Query: 3677 ETLHKR-EEIT-IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734 + LHKR IT + + + VE N+ + G PV G P I W N Sbjct: 1263 KLLHKRYSSITRLSIRRQQIRQAAVERGANLII--GCPVS--------GRPLPAIQWLRN 1312 Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG 3777 G + SR + G I I I + AGEY C N G Sbjct: 1313 GLKISNDSRQVIVG--GVIM--IRDIQLQHAGEYFCYVKNTAG 1351 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584 V G + + V+G + WL+NG K+ D R I+ ++I + Q +G+Y Sbjct: 1287 VERGANLIIGCPVSGRPLPAIQWLRNGLKISNDSRQVIVGG----VIMIRDIQLQHAGEY 1342 Query: 4585 ECVAINSAGE 4594 C N+AGE Sbjct: 1343 FCYVKNTAGE 1352 Score = 33.5 bits (73), Expect = 4.3 Identities = 16/44 (36%), Positives = 21/44 (47%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154 PV +S+ VT EG C TG P+P V W +G + G Sbjct: 179 PVSISVGSDVTAIEGVTVSIECNATGVPRPEVFWSKDGLRLYPG 222 Score = 33.1 bits (72), Expect = 5.7 Identities = 71/339 (20%), Positives = 126/339 (37%), Gaps = 31/339 (9%) Query: 3580 RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDA-GLYTCKATNRH 3638 R IP+ D S + + +LTGSR+ TI+ + + ++++D L + Sbjct: 60 RDIPLGDGSPTIARIADNATVLTGSRL-TIDCVATGVPKPSIIWRKDGRELIGAGSYMAP 118 Query: 3639 GEATVSCKLQVKGRQGII-LEPQLPSHFKSGTESIQKLEETLHKREEITIEDEK--PNPP 3695 G ++ + G+ P S + +I+ ++ L + TI K N Sbjct: 119 GNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRISRPTIGSTKSTDNMN 178 Query: 3696 RFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIAL 3755 ++ + ++ EG V +C G P + W +G G N L Sbjct: 179 PVSISVGSDVTAIEGVTVSIECNA--TGVPRPEVFWSKDGLRLYPGEYPVLENK----TL 232 Query: 3756 DIDYIYARDAGEYTCRATNKWG--SATTTAKITCSAKRDIVL-ESQLPQGMSGEKIKELE 3812 I D+G YTC A + G S ++ +I + +V L S ++ ++ Sbjct: 233 IITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDKQSRLVFGVMSLKYSFSAAEVPIIQ 292 Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872 R +D ++ + + Q+ S GV + P IEW GK++ Sbjct: 293 --RTTDKVEKSDMKPVDVRIGGQVTS-----LSGVDITLNCSARGLPPPDIEWMNGGKMI 345 Query: 3873 PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 TV V +++ + DSG Y C A N G Sbjct: 346 -------TVQGPRLVLRNVM---SSDSGNYTCIASNVVG 374 Score = 33.1 bits (72), Expect = 5.7 Identities = 44/195 (22%), Positives = 73/195 (37%), Gaps = 20/195 (10%) Query: 659 RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718 R G P + W G +A ++ G + L+ +++ D G YTC A +A G Sbjct: 1178 RCAAYGSPKPSVTWYVVGSERKAD---LTVLPDGTLELE--NVDFMDEGNYTCVARNAYG 1232 Query: 719 VAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQD 778 VT R+T P L D QH + + ++ S + Q Sbjct: 1233 ---------VTSRSTNVTVLVPPSILDNF--FADAILVQHSKLLHKRYSSITRLSIRRQQ 1281 Query: 779 LGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAE 838 + + R A+ P ++W ++G I+ SR + G V + I ++ + Sbjct: 1282 IRQAAVERGANLIIGCPVSGRPLPAIQWLRNGLKISNDSRQVIV---GGV-IMIRDIQLQ 1337 Query: 839 DAGSYTVRAVNKLGE 853 AG Y N GE Sbjct: 1338 HAGEYFCYVKNTAGE 1352 >SB_45852| Best HMM Match : I-set (HMM E-Value=0) Length = 1122 Score = 87.0 bits (206), Expect = 3e-16 Identities = 187/849 (22%), Positives = 312/849 (36%), Gaps = 161/849 (18%) Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161 A ++S + DSG Y VA N G A S+++T+ + I+ + L K I Sbjct: 294 AFTLSSTESADSGRYDCVATNLKGTAMASSAITIHDK--IEKRVAPKILSSKKNLIA--- 348 Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221 S++K +F + + EGK++ L+C +G P V WF NG +VT Sbjct: 349 -----------SENKRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVT 395 Query: 1222 VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281 K + G AL II T+ + G+Y ++ N G ++ V+ Sbjct: 396 ESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVV----------- 442 Query: 1282 EQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQT 1341 +IQL +++ +T++ + T+ GT + C G Sbjct: 443 GPVAPKIQLSNKVYSVVDPLKKPLTLLVG-------DTLTTLSGTRTSISC--PATGFPN 493 Query: 1342 MRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401 + W NG+ + G + D L L + ED+GVY C A+N G+A + + Sbjct: 494 PLIRWSRNGESVVPGGHLK----IDGSKLLLTNPQKEDNGVYKCLASNPGGDATATSNMT 549 Query: 1402 VIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQH 1461 I + +P+ ++ T R + II VT VI+G Sbjct: 550 FI-------DPSNPNITLSRDVVKSTIREAVSVIIGSDVT--------------VIDGST 588 Query: 1462 VHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521 + +C V W +NG ++ L + +L G C A Sbjct: 589 ILIQCSAVGVPKPTF--SWIRNGVNLSNSEE----------VLKLSNLRVGGDGSIKCVA 636 Query: 1522 VNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKY--HRTDMVDEVTTQAPI 1579 N GTD LT +LE R + + + + + P+ Sbjct: 637 SNFYGTDSAETTLT---------------------ILEPRGPFIESSSQSLSSINSTDPV 675 Query: 1580 CTTSLKNVEIKEGQRAHFERRLIPVSDATLKV-EWYHNNKPLKSGSRFTETNNFGFVALD 1638 N+ + G F + + + V W +N+ + SG + + AL Sbjct: 676 RALIGSNLTVLAGA---FVTLVCNATGLPMPVASWKYNSGDITSGHVTIQGS-----ALR 727 Query: 1639 IMSCLPEDSGTYTCRAINALGE-AVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKY 1697 I DSG Y C A + GE VTS + ++ G++P + + D + Sbjct: 728 ITKTSNADSGVYACLARSPAGEVTVTSHLILI------------AGSIPVITRSADVIED 775 Query: 1698 QRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN 1757 Q + V V + I++ +G PK V W G P+ S+ Sbjct: 776 QSKFSNLTVTIGTKVTLLASSSIKIT----------CKAIGIPKPVVTWTMRGRPVVPSD 825 Query: 1758 RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESA 1817 R+ + AL + D+G C A N G V SS + V L Q++ Sbjct: 826 RVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLITV---LGTYLRPQNQHC 878 Query: 1818 LQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMR 1877 + I QL+ +Q +V + +T L+G T C+ P P Sbjct: 879 GKVITQLD----HQNPVTSKVGAS-----VTALSGVT-------VTLVCQAIGLPVPT-- 920 Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 + W FNGK L S + +N ++ I+ EDSG+Y C A + GQ + + ++ Sbjct: 921 ITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSVIKIE 976 Query: 1938 SKESIIRDS 1946 S ++S Sbjct: 977 GLLSYKKNS 985 Score = 79.4 bits (187), Expect = 7e-14 Identities = 121/468 (25%), Positives = 170/468 (36%), Gaps = 80/468 (17%) Query: 1734 LIPV-GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792 + PV G P +V W +NG PI + ++ T V N + DSG Y+CRA+N LG Sbjct: 159 ICPVEGLPPPKVTWAKNG-PIASGDKFTIARSTDLV-FNSGKASVFDSGRYSCRAVNNLG 216 Query: 1793 -EAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLN 1851 + S F + KA I L+D E VN F + Sbjct: 217 QDTAYSEVTFREPKA------------PTIMTLDDK--------FEFIVNAT--FTVTIG 254 Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911 G S C E P P V W G LQ G R A + + Sbjct: 255 ANVSALRGSSITLTCTAEGLPVP--FVVWKKGGATLQQGGR----------AFTLSSTES 302 Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDD 1971 DSG Y C A N G A++S + + K +EK + S K + + Sbjct: 303 ADSGRYDCVATNLKGTAMASSAITIHDK------------IEKRVAPKILSSKKNLIASE 350 Query: 1972 SFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031 + + G N + EG + L+ + P V W+ NG V + K + Sbjct: 351 NKRLFYHIIG---GNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLKVDPN 405 Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQEL 2091 G AL I+ AE+ G YMCK+ N GE + TS V KIQ Sbjct: 406 TG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVVGPVA-----------PKIQLS 452 Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151 K P ++P+ L +L L G R C +P I W NG+ Sbjct: 453 NKV-----YSVVDPLKKPLTLLVGDTLTTL-SGTRTSISCPATGFPNP--LIRWSRNGES 504 Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199 + G + L + ED+G Y C A+N G+A T + Sbjct: 505 VVPGGHLKIDGS----KLLLTNPQKEDNGVYKCLASNPGGDATATSNM 548 Score = 78.6 bits (185), Expect = 1e-13 Identities = 117/468 (25%), Positives = 181/468 (38%), Gaps = 73/468 (15%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P+ V+W RN V + R + Y + N E SG Y C A N+ G A + Sbjct: 47 GFPQPIVQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGELSGEYACLATNKGGFAAVT 106 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857 + L +++ + S + +L S R+ V V + +T Sbjct: 107 TDLQIKAPFKPFIRSTWVTGSVGTHKLLKS-----RDPVIVTIGDKVETLT--------- 152 Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT--SNDFGFAALDILTVYGEDSG 1915 G C +E P P +V W NG + SG ++ S D F + +V+ DSG Sbjct: 153 -GTEVSIICPVEGLPPP--KVTWAKNGPIA-SGDKFTIARSTDLVFNS-GKASVF--DSG 205 Query: 1916 EYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVV 1975 Y+C+A+NNLGQ + + + E I L+D + + + +F V Sbjct: 206 RYSCRAVNNLGQDTAYSEVTFR-----------EPKAPTIMTLDDKFEF---IVNATFTV 251 Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035 G N G + L T T P V W G +QQG R Sbjct: 252 T---IGA---NVSALRGSSITL--TCTAEGLPVPFVVWKKGGATLQQGGR---------- 293 Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095 A + + D+G Y C ATN G A+ +S++ + D ++++ KI +K Sbjct: 294 AFTLSSTESADSGRYDCVATNLKGTAMASSAITIH-------DKIEKRVAPKILSSKK-- 344 Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155 I E + +F + + EG +C I P + WF NG + Sbjct: 345 --NLIASEN---KRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTES 397 Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203 + + G AL I+ AE+ G YMCK+ N GE + T V G Sbjct: 398 DTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVVG 443 Score = 74.5 bits (175), Expect = 2e-12 Identities = 76/307 (24%), Positives = 118/307 (38%), Gaps = 48/307 (15%) Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338 +G+ Q G P+P +W +NG L NS + L++ N + G Sbjct: 585 DGSTILIQCSAVGVPKPTFSWIRNGVNLSNSEE----------VLKLSNLRVGGDGSIKC 634 Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398 +A N G L + P +++ SQ ++ + P + Sbjct: 635 VASNFYGTDSAETTLTILEPRGPFIESS-SQSLSSINSTD-------------PVRALIG 680 Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458 + V G C TG P P +W N I + V G+ AL IT + + Sbjct: 681 SNLTVLAGAFVTLVCNATGLPMPVASWKYNSGDITSGH-----VTIQGS-ALRITKTSNA 734 Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE------RFSTLNVREGEPVVLNA 512 DSGV C+AR+ +GE L +I V + + +FS L V G V L A Sbjct: 735 DSGVYACLARSPAGEVTVTSHLILIAGSIPVITRSADVIEDQSKFSNLTVTIGTKVTLLA 794 Query: 513 --------RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 +A+G P P +TW G P++P+ + + + L + A+D CT Sbjct: 795 SSSIKITCKAIGIPKPVVTWTMRGRPVVPSDRVMVE----KNALVFLKILATDTGNVVCT 850 Query: 565 AQNVAGS 571 A N GS Sbjct: 851 ANNARGS 857 Score = 73.7 bits (173), Expect = 3e-12 Identities = 98/404 (24%), Positives = 151/404 (37%), Gaps = 48/404 (11%) Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494 +G P P + W + N PI + F I ST + + V DS ++ A N G Sbjct: 163 EGLPPPKVTWAK-NGPIASGDKFTIAR-STDLVFNSGKASVFDSGRYSCRAVNNLGQDTA 220 Query: 4495 SANLVVEEKRR-------QGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVY 4546 + + E + IV +FT+T NV+ G + L G V Sbjct: 221 YSEVTFREPKAPTIMTLDDKFEFIVNATFTVTIGANVSALRGSSITLTCTAEGLPVPFVV 280 Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606 W K G +Q R +TL E+ DSG+Y+CVA N G A + + Sbjct: 281 WKKGGATLQQGGR--------AFTLSSTES--ADSGRYDCVATNLKGTAMASSAITIHDK 330 Query: 4607 ATKD-KPKPQTKAANAPPEIIEPLKDKIVA------EGQAIEFSCKIVGKPLPTVQWYKG 4659 K PK + N + L I+ EG+ +E C +G P P V W+ Sbjct: 331 IEKRVAPKILSSKKNLIASENKRLFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFIN 390 Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR----------VTVAAK 4709 + S ++ L I E E++G Y C + N AG VA K Sbjct: 391 GSAVTESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVVGPVAPK 448 Query: 4710 LKVTQPDQADNLPALTPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764 ++++ + P PL +V G T P I+W R G + Sbjct: 449 IQLSNKVYSVVDPLKKPLTLLVGDTLTTLSGTRTSISCPATGFPNPLIRWSRNGESV--V 506 Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 P + +G+ LL+ N +ED G + C A+ G ++ + Sbjct: 507 PGGHLKIDGSK--LLLTNPQKEDNGVYKCLASNPGGDATATSNM 548 Score = 73.7 bits (173), Expect = 3e-12 Identities = 65/277 (23%), Positives = 103/277 (37%), Gaps = 33/277 (11%) Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N + EG D + Q G P+P VTWF NG + S+ ++ N L + + Sbjct: 362 NITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV--DPNTGALSIIEITAEEQ 419 Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393 G Y ++N G + + Y V P +Q Y + + P Sbjct: 420 GQYMCKSKNIAGEDLETSYTTVVGPVAPKIQLSNKVY-------------SVVDPLKKPL 466 Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453 + V G T C TG P P + W N + + KI L++T Sbjct: 467 TLLVGDTLTTLSGTRTSISCPATGFPNPLIRWSRNGESVVPGGHLKI-----DGSKLLLT 521 Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIE--------KEQVVAPKFVERFSTL----- 500 N D+GV C+A N G+ + I+ VV E S + Sbjct: 522 NPQKEDNGVYKCLASNPGGDATATSNMTFIDPSNPNITLSRDVVKSTIREAVSVIIGSDV 581 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537 V +G +++ AVG P P +W ++GV + + E+ Sbjct: 582 TVIDGSTILIQCSAVGVPKPTFSWIRNGVNLSNSEEV 618 Score = 68.1 bits (159), Expect = 2e-10 Identities = 85/415 (20%), Positives = 149/415 (35%), Gaps = 47/415 (11%) Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481 + E + + G P P + W+ + S ++ +T ++ II ++ E+ + Sbjct: 365 ILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDP-NTGALSII-EITAEEQGQY 422 Query: 4482 AAVAENRGG----------TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLV 4531 ++N G + + + K + P L + SG Sbjct: 423 MCKSKNIAGEDLETSYTTVVGPVAPKIQLSNKVYSVVDPLKKPLTLLVGDTLTTLSGTRT 482 Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591 + TG + W +NG+ V P KI DG+ LL+ +D+G Y+C+A N Sbjct: 483 SISCPATGFPNPLIRWSRNGESVVPGGHLKI---DGS-KLLLTNPQKEDNGVYKCLASNP 538 Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL--KDKIVAEGQAIEFSCKIVGK 4649 G+A + P+ + + + E + + D V +G I C VG Sbjct: 539 GGDATATSNMTFIDPSNPNITLSRDVVKSTIREAVSVIIGSDVTVIDGSTILIQCSAVGV 598 Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709 P PT W + + S E L++S +G KCVA N G + Sbjct: 599 PKPTFSWIRNGVNLSNS----------EEVLKLSNLRVGGDGSIKCVASNFYGTDSAETT 648 Query: 4710 LKVTQP---------DQADNLPALTPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWL 4755 L + +P ++ + P+R ++ V G T P W Sbjct: 649 LTILEPRGPFIESSSQSLSSINSTDPVRALIGSNLTVLAGAFVTLVCNATGLPMPVASWK 708 Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 I T I + L I T D+G + C A + AG+V ++ L++ Sbjct: 709 YNSGDI--TSGHVTIQ---GSALRITKTSNADSGVYACLARSPAGEVTVTSHLIL 758 Score = 67.7 bits (158), Expect = 2e-10 Identities = 69/320 (21%), Positives = 131/320 (40%), Gaps = 47/320 (14%) Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N + GA +G P P +W N + + + T + LR+ T +DS Sbjct: 682 NLTVLAGAFVTLVCNATGLPMPVASWKYNSGDITSGH-----VTIQGSALRITKTSNADS 736 Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKA--LA 391 G Y LA +P G + + +L + + + + RS + + Q + + + I K LA Sbjct: 737 GVYACLARSPAGEVTVTSHLILIAGSIPVIT--RSADVIEDQSKFSNLTVTIGTKVTLLA 794 Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 +K+ C+ G P P VTW + R + + +++V ++ AL+ Sbjct: 795 SSSIKIT--------------CKAIGIPKPVVTWTMRGRPVVP--SDRVMVEKN---ALV 835 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVI----EKEQVVAPKFVERF---------- 497 + +D+G V C A N G + V+ + K + + Sbjct: 836 FLKILATDTGNVVCTANNARGSDVASSLITVLGTYLRPQNQHCGKVITQLDHQNPVTSKV 895 Query: 498 -STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556 +++ G V L +A+G P P ITW +G P+ + ++ + ++ I +A++ Sbjct: 896 GASVTALSGVTVTLVCQAIGLPVPTITWTFNGKPLTSHGQVTVTN----QSVTIIKARSE 951 Query: 557 DAAWYQCTAQNVAGSTATRA 576 D+ Y C A + G + R+ Sbjct: 952 DSGDYVCNATSANGQGSARS 971 Score = 67.3 bits (157), Expect = 3e-10 Identities = 97/411 (23%), Positives = 153/411 (37%), Gaps = 51/411 (12%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P P+++W R + + + ++I + E S +A +A N+GG A + Sbjct: 47 GFPQPIVQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGELSGEYACLATNKGGFAAVT 106 Query: 4496 ANLVVEEK-----RRQGRGGIV---------PPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541 +L ++ R G V P V +G V + V G Sbjct: 107 TDLQIKAPFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKVETLTGTEVSIICPVEGLP 166 Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601 P V W KNG D D + + DSG+Y C A+N+ G+ +E Sbjct: 167 PPKVTWAKNGPIASGDKFTIARSTDLVFNSGKASVF--DSGRYSCRAVNNLGQDTAYSEV 224 Query: 4602 VVSLPATKDKPKPQTK---AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 P K NA + + G +I +C G P+P V W K Sbjct: 225 TFREPKAPTIMTLDDKFEFIVNATFTVTIGANVSAL-RGSSITLTCTAEGLPVPFVVWKK 283 Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG------RVTVAAKL-K 4711 G ++ Q R +TL +E+ D G Y CVA N G +T+ K+ K Sbjct: 284 GGATLQ-----QGGRA---FTLSSTES--ADSGRYDCVATNLKGTAMASSAITIHDKIEK 333 Query: 4712 VTQP---DQADNLPALTPLR--------DIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760 P NL A R +I + EG+ + + KP + W G+ Sbjct: 334 RVAPKILSSKKNLIASENKRLFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFINGSA 393 Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVV 4810 + E+ ++ + N L I E+ G + C++ AG+ +ETS VV Sbjct: 394 VTESDTLKV--DPNTGALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVV 442 Score = 66.9 bits (156), Expect = 4e-10 Identities = 120/536 (22%), Positives = 198/536 (36%), Gaps = 84/536 (15%) Query: 3400 LEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWN 3459 +ED ++ + ++ K T + N L +G T P V+W N Sbjct: 2 VEDPVIHAEKATIRAVD-KVTSLTSSIGNAITLLKGSRVTLVCHATGFPQPI--VQWTRN 58 Query: 3460 GKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNII 3519 L R + + ++ + E SGEY C A N G A T ++++ Sbjct: 59 KVDLTGRMRQLRYNVTHYGVIIDTRFNGELSGEYACLATNKGGFAAVTTDLQIKAPFKPF 118 Query: 3520 LESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFEC 3579 + S G GT K+ L+ + T+ + E+ T T +I Sbjct: 119 IRSTWVTGSVGT-HKL--LKSRDPVIVTIGDKVET-----LTGTEVSIICPVEG------ 164 Query: 3580 RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHG 3639 +P +V W NG P+ +G + TI ++ G D+G Y+C+A N G Sbjct: 165 --LP----PPKVTWAKNG-PIASGDKF-TIARSTDLVFNSGKASVFDSGRYSCRAVNNLG 216 Query: 3640 EATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTV 3699 + T ++ + EP+ P+ TL + E + FTV Sbjct: 217 QDTAYSEVTFR-------EPKAPTIM------------TLDDKFEFIVN------ATFTV 251 Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759 I N+ G + C E G P + W G G R TL+ Sbjct: 252 TIGANVSALRGSSITLTCTAE--GLPVPFVVWKKGGATLQQGGRAFTLSS---------- 299 Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819 + D+G Y C ATN G+A ++ IT +KI++ +I + Sbjct: 300 TESADSGRYDCVATNLKGTAMASSAITIH-----------------DKIEKRVAPKILSS 342 Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879 K+ I S + I + EG E + PK + W+ NG + + Sbjct: 343 -KKNLIASENKRLFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLK 401 Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDF--TKATISCKKLPDIILQNQV 3933 + G +L I+ + AE+ G+Y+C++ N GED + T+ P I L N+V Sbjct: 402 VDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVVGPVAPKIQLSNKV 455 Score = 65.7 bits (153), Expect = 9e-10 Identities = 104/495 (21%), Positives = 171/495 (34%), Gaps = 64/495 (12%) Query: 4349 DPSESTVHGKEVHVAKQKQ---TQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPV 4405 DP+ + E+ +Q Q K + G+ ++ T T + K Q +V V Sbjct: 403 DPNTGALSIIEITAEEQGQYMCKSKNIAGE-DLETSYT-TVVGPVAPKIQLSNKVYS-VV 459 Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465 P K P+ + G P PLI+W R + +I Sbjct: 460 DPLKKPLTLLVGDTLTTLSGTRTSISCPATGFPNPLIRWSRNGESVVPGGHLKIDG---- 515 Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLV--------VEEKRRQGRGGIVPPSFT 4517 S L++ ED+ V+ +A N GG A ++N+ + R + I Sbjct: 516 SKLLLTNPQKEDNGVYKCLASNPGGDATATSNMTFIDPSNPNITLSRDVVKSTIREAVSV 575 Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577 + +V V G + + G W++NG + EE L + Sbjct: 576 IIGSDVTVIDGSTILIQCSAVGVPKPTFSWIRNGVNLSNS------EE----VLKLSNLR 625 Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATK--DKPKPQTKAANAPPEIIEPLKDKI-V 4634 G +CVA N G + + P + + N+ + + + V Sbjct: 626 VGGDGSIKCVASNFYGTDSAETTLTILEPRGPFIESSSQSLSSINSTDPVRALIGSNLTV 685 Query: 4635 AEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 G + C G P+P W Y + Q S LRI++ D G Y Sbjct: 686 LAGAFVTLVCNATGLPMPVASWKYNSGDITSGHVTIQGS------ALRITKTSNADSGVY 739 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI----- 4748 C+A + AG VTV + L + A ++P +T D++ + + + I +K+ Sbjct: 740 ACLARSPAGEVTVTSHLILI----AGSIPVITRSADVIEDQSKFSNLTVTIGTKVTLLAS 795 Query: 4749 -------------KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795 KP + W G P P +++ E N V L DTG C A Sbjct: 796 SSIKITCKAIGIPKPVVTWTMRGR--PVVPSDRVMVEKNALVFL--KILATDTGNVVCTA 851 Query: 4796 TTAAGQVETSAKLVV 4810 A G S+ + V Sbjct: 852 NNARGSDVASSLITV 866 Score = 65.7 bits (153), Expect = 9e-10 Identities = 75/343 (21%), Positives = 123/343 (35%), Gaps = 49/343 (14%) Query: 250 VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309 +Q+S ++ + P+ P G +G P P + W +NG+ ++ Sbjct: 449 IQLSNKVYSVVDPLKKPLTLLVGDTLTTLSGTRTSISCPATGFPNPLIRWSRNGESVVPG 508 Query: 310 NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369 +I + + L + N QK D+G Y LA NP G + + P+ + R Sbjct: 509 GHLKI----DGSKLLLTNPQKEDNGVYKCLASNPGGDATATSNMTFIDPSNPNITLSR-- 562 Query: 370 YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIND 429 D + E + V + D V +G C G P P +W Sbjct: 563 ---DVVKSTIREAVS----------VIIGSDVTVIDGSTILIQCSAVGVPKPTFSW---- 605 Query: 430 RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489 IR+ N L N L ++N+ + G + CVA N G + + L ++E Sbjct: 606 --IRNGVN---LSN--SEEVLKLSNLRVGGDGSIKCVASNFYGTDSAETTLTILEPRGPF 658 Query: 490 APKFVERFSTLN--------------VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP 535 + S++N V G V L A G P P +W+ + I Sbjct: 659 IESSSQSLSSINSTDPVRALIGSNLTVLAGAFVTLVCNATGLPMPVASWKYNSGDITSG- 717 Query: 536 ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 H S L I + +D+ Y C A++ AG + L Sbjct: 718 ----HVTIQGSALRITKTSNADSGVYACLARSPAGEVTVTSHL 756 Score = 63.3 bits (147), Expect = 5e-09 Identities = 106/452 (23%), Positives = 166/452 (36%), Gaps = 71/452 (15%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 V+W N +T R Y+ Y + E SG Y +A N G A ++ + ++ Sbjct: 53 VQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGELSGEYACLATNKGGFAAVTTDLQIK 112 Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196 + S +V ++ KS+ + + + G + Sbjct: 113 A---------------PFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKVETLTGTEVS 157 Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256 + C +E G P +V W NG + G +F V + A+ D+G Y+ RAVN Sbjct: 158 IICPVE--GLPPPKVTWAKNG-PIASGDKFTIARSTDLV-FNSGKASVFDSGRYSCRAVN 213 Query: 1257 HLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRA 1316 +LG + V T E I L+D +T+ Sbjct: 214 NLGQDTAYSEV-----------TFREPKAPTIMTLDDKFEFIVNATFTVTIGA------- 255 Query: 1317 LHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVY 1376 N+ + G+++ L C + G V W G ++ G R A L S Sbjct: 256 --NVSALRGSSITLTCTAE--GLPVPFVVWKKGGATLQQGGR----------AFTLSSTE 301 Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436 DSG Y C ATN G A+ S A+ + D I + P L KK I Sbjct: 302 SADSGRYDCVATNLKGTAMASSAITI---HDKIEKRVAPKILSS----------KKNLIA 348 Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496 E+ K F ++EG+ + +C + V WF NG VT + Sbjct: 349 SEN---KRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLKVD 403 Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528 + G AL II++ AE+ G Y C++ N+ G D Sbjct: 404 PNTG--ALSIIEITAEEQGQYMCKSKNIAGED 433 Score = 60.9 bits (141), Expect = 2e-08 Identities = 72/311 (23%), Positives = 110/311 (35%), Gaps = 52/311 (16%) Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339 G + + G P P+VTW KNG I S I DSG Y+ Sbjct: 153 GTEVSIICPVEGLPPPKVTWAKNGP--IASGDKFTIARSTDLVFNSGKASVFDSGRYSCR 210 Query: 340 AENPNGCIVTSGYLAVESPTESYVQ--DQRSQYITDTQQRETEERIEISEKALAPQFVKV 397 A N G + P + D + ++I + T I + AL Sbjct: 211 AVNNLGQDTAYSEVTFREPKAPTIMTLDDKFEFIVNATFTVT---IGANVSAL------- 260 Query: 398 CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457 G C G P P V W + + G A +++ Sbjct: 261 -------RGSSITLTCTAEGLPVPFVVWKKGGATL-----------QQGGRAFTLSSTES 302 Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEK-EQVVAPKFVERFSTL---------------- 500 +DSG CVA N G + + +K E+ VAPK + L Sbjct: 303 ADSGRYDCVATNLKGTAMASSAITIHDKIEKRVAPKILSSKKNLIASENKRLFYHIIGGN 362 Query: 501 -NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559 + EG+ + L ++GTP P +TW +G + + L++ + GA L I A + Sbjct: 363 ITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTGA--LSIIEITAEEQG 420 Query: 560 WYQCTAQNVAG 570 Y C ++N+AG Sbjct: 421 QYMCKSKNIAG 431 Score = 60.5 bits (140), Expect = 3e-08 Identities = 146/614 (23%), Positives = 235/614 (38%), Gaps = 101/614 (16%) Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYP-E 1378 I ++G+ V L C G V+W N K TG + Y + + + + + E Sbjct: 31 ITLLKGSRVTLVCHA--TGFPQPIVQWTRN-KVDLTGRMRQLRYNVTHYGVIIDTRFNGE 87 Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDE 1438 SG Y C ATN+ G A + L++ A + S +G L K D Sbjct: 88 LSGEYACLATNKGGFAAVTTDLQIKAPFKPFIRSTWVTGSVGTHKL-----LKSRD---- 138 Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498 P VT +E + G V C +E + KV W KNG P+ G +F Sbjct: 139 -----PVIVTIGDKVET-LTGTEVSIICPVEGLPPP--KVTWAKNG-PIASGDKFTIARS 189 Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVL 1558 V + DSG Y+CRAVN +G D +T R E I L Sbjct: 190 TDLV-FNSGKASVFDSGRYSCRAVNNLGQDTAYSEVTFR-----------EPKAPTIMTL 237 Query: 1559 EDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNK 1618 +D+ ++ + VT A + ++L+ I A E +P V W Sbjct: 238 DDKFEF-IVNATFTVTIGANV--SALRGSSITLTCTA--EGLPVPF------VVWKKGGA 286 Query: 1619 PLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE 1678 L+ G R A + S DSG Y C A N G A+ S +H K +E Sbjct: 287 TLQQGGR----------AFTLSSTESADSGRYDCVATNLKGTAMASSAITIHDK----IE 332 Query: 1679 SQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVG 1738 + P++ +SK +++++ + + + +I + E + E + +G Sbjct: 333 KR---VAPKIL----SSKKNLIASENKRL----FYHIIGGNITILEGK--DLELQCPSIG 379 Query: 1739 DPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798 PK V W NG + S+ L + G AL++ + E+ G Y C++ N GE Sbjct: 380 TPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGE----- 432 Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS- 1857 LE+ + + + + + + Q V V+ + +T L G T + Sbjct: 433 ----------DLETSYTTVVGPV-----APKIQLSNKVYSVVDPLKKPLTLLVGDTLTTL 477 Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917 G C +P+P +R W NG+ + G + + L + ED+G Y Sbjct: 478 SGTRTSISCPATGFPNPLIR--WSRNGESVVPGGHLKIDG----SKLLLTNPQKEDNGVY 531 Query: 1918 TCKAINNLGQAVSS 1931 C A N G A ++ Sbjct: 532 KCLASNPGGDATAT 545 Score = 58.8 bits (136), Expect = 1e-07 Identities = 180/848 (21%), Positives = 296/848 (34%), Gaps = 159/848 (18%) Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027 A T+ S D+G Y C A N G A S+ +TI K +EK A Sbjct: 294 AFTLSSTESADSGRYDCVATNLKGTAMASSAITIHDK------------IEK----RVAP 337 Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT 1087 + + + K F + G I+EG+ E + V W+ NG +T Sbjct: 338 KILSSKKNLIASENKRLFYHIIGGNITILEGKD--LELQCPSIGTPKPAVTWFINGSAVT 395 Query: 1088 SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIH 1147 ++ ++ + G AL I + AE+ G Y ++N AGE L S T + Sbjct: 396 ESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGE-DLETSYTTVVGPVAPKIQLS 452 Query: 1148 RGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDP 1207 +Y V+P+ KP+ + + + G + C G P Sbjct: 453 NKVY---------SVVDPL--------KKPLTLL-VGDTLTTLSGTRTSISC--PATGFP 492 Query: 1208 TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267 + W NG SV G K L + + D G Y A N G A ++ + Sbjct: 493 NPLIRWSRNGESVVPGGHLK----IDGSKLLLTNPQKEDNGVYKCLASNPGGDATATSNM 548 Query: 1268 RVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTN 1327 I+ S+ I L D + T +RE ++V+ ++ ++G+ Sbjct: 549 TFIDPSN-----------PNITLSRDVVKST--IREAVSVIIG-------SDVTVIDGST 588 Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQA 1387 + ++C VG W NG + L L ++ G C A Sbjct: 589 ILIQC--SAVGVPKPTFSWIRNGVNLSNSEE----------VLKLSNLRVGGDGSIKCVA 636 Query: 1388 TNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFV 1447 +N G L ++ + +ES S + + T + +I ++T Sbjct: 637 SNFYGTDSAETTLTILEPRGPFIESSSQS----LSSINSTDPVRA--LIGSNLT------ 684 Query: 1448 TRPKSIENVIEGQHVHFECKLEPVTDSNLKV-EWFKNGQPVTIGHRFRPIHDFGYVALDI 1506 V+ G V C T + V W N +T GH + G AL I Sbjct: 685 --------VLAGAFVTLVCN---ATGLPMPVASWKYNSGDITSGH----VTIQG-SALRI 728 Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCR--LTCRSTTDIVRSTQNEAGLEQIQVLEDRSKY 1564 DSG+Y C A + G V+ L S I RS V+ED+SK+ Sbjct: 729 TKTSNADSGVYACLARSPAGEVTVTSHLILIAGSIPVITRSA---------DVIEDQSKF 779 Query: 1565 HRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGS 1624 +++ + T+ + +S + K + V W +P+ Sbjct: 780 --SNLTVTIGTKVTLLASSSIKITCK------------AIGIPKPVVTWTMRGRPVVPSD 825 Query: 1625 RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGA 1684 R N AL + L D+G C A NA G V S + V YL Q++ Sbjct: 826 RVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLITV---LGTYLRPQNQHC 878 Query: 1685 LPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRV 1744 + QL+ Q+ V ++ + + V A +G P + Sbjct: 879 GKVITQLDH---------QNPVTSKVGASVTALSGVTVTLVCQA--------IGLPVPTI 921 Query: 1745 EWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804 W NG P+ + ++T + ++ + EDSG Y C A + G+ S + ++ Sbjct: 922 TWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSVIKIEG 977 Query: 1805 KASLQLES 1812 S + S Sbjct: 978 LLSYKKNS 985 Score = 58.4 bits (135), Expect = 1e-07 Identities = 70/306 (22%), Positives = 119/306 (38%), Gaps = 21/306 (6%) Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY--PQD 4580 + + G V L TG V W +N KV R + L + T+ +I++ + Sbjct: 31 ITLLKGSRVTLVCHATGFPQPIVQWTRN--KVDLTGRMRQLRYNVTHYGVIIDTRFNGEL 88 Query: 4581 SGKYECVAINSAGEARCDAECVVSLP------ATKDKPKPQT-KAANAPPEIIEPLKDKI 4633 SG+Y C+A N G A + + P +T T K + +I + DK+ Sbjct: 89 SGEYACLATNKGGFAAVTTDLQIKAPFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKV 148 Query: 4634 -VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692 G + C + G P P V W K + K F ++R+ D +A D G Sbjct: 149 ETLTGTEVSIICPVEGLPPPKVTWAKNGPIASGDK-FTIARSTD-LVFNSGKASVFDSGR 206 Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS--KIKP 4750 Y C A N+ G+ T +++ +P +A + L + +V +++ Sbjct: 207 YSCRAVNNLGQDTAYSEVTFREP-KAPTIMTLDDKFEFIVNATFTVTIGANVSALRGSSI 265 Query: 4751 TIQWLREGALIPET---PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807 T+ EG +P + +G A L +T D+G + C AT G S+ Sbjct: 266 TLTCTAEGLPVPFVVWKKGGATLQQGGRAFTL-SSTESADSGRYDCVATNLKGTAMASSA 324 Query: 4808 LVVKSK 4813 + + K Sbjct: 325 ITIHDK 330 Score = 57.6 bits (133), Expect = 2e-07 Identities = 69/309 (22%), Positives = 116/309 (37%), Gaps = 37/309 (11%) Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH-EIITTHNHTTLRVRNTQKSDSGH 335 L +G+ +G P+P V W +N L + TH + R + SG Sbjct: 33 LLKGSRVTLVCHATGFPQPIVQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGEL-SGE 91 Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395 Y LA N G + L +++P + ++ RS ++T + T + + K+ P V Sbjct: 92 YACLATNKGGFAAVTTDLQIKAPFKPFI---RSTWVTGSVG--THKLL----KSRDPVIV 142 Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455 + + G C V G P P+VTW N D K + S + Sbjct: 143 TIGDKVETLTGTEVSIICPVEGLPPPKVTWAKNGPIASGD---KFTIARSTDLVFNSGKA 199 Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-------------STLNV 502 ++ DSG +C A N G+ + E + ++F + ++ Sbjct: 200 SVFDSGRYSCRAVNNLGQDTAYSEVTFREPKAPTIMTLDDKFEFIVNATFTVTIGANVSA 259 Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562 G + L A G P P + W+K G + G A TL +++D+ Y Sbjct: 260 LRGSSITLTCTAEGLPVPFVVWKKGGA--------TLQQGGRAFTLS--STESADSGRYD 309 Query: 563 CTAQNVAGS 571 C A N+ G+ Sbjct: 310 CVATNLKGT 318 Score = 57.2 bits (132), Expect = 3e-07 Identities = 92/436 (21%), Positives = 166/436 (38%), Gaps = 59/436 (13%) Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894 ++ T DSG Y C ATN KG+A S ++ T H + +E+ + Sbjct: 297 LSSTESADSGRYDCVATNLKGTAMASSAI-----------TIH-------DKIEKRVAPK 338 Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954 + ++ + K + I ++EG+ L L Q P + W+ NG + Sbjct: 339 ILSSKKNLIASEN--KRLFYHIIGGNITILEGKDLEL--QCPSIGTPKPAVTWFINGSAV 394 Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQ 3014 + K+ + G L ++++ + G Y CK+ N GE +S Y T + + Q Sbjct: 395 TESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETS--YTTVVGPVAPKIQ 450 Query: 3015 HPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIP 3074 K+ ++ D L+K T + D + G S Sbjct: 451 LSN------KVYSVVDPLKKP--------------LTLLVGDTLTTLSG--TRTSISCPA 488 Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 TG + +I W NG+++ ++ G +L + + D+G Y C A+N G A Sbjct: 489 TGFPNPLIRWSRNGESVVPGGHLKID---GSKLL-LTNPQKEDNGVYKCLASNPGGDATA 544 Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193 + + +D S P T ++ +++ S V +D + I+ G P Sbjct: 545 TSNMTFIDPS---NPNITLSRDVVKSTIREAVSVIIGSDVTVIDGSTILIQCSAVGVPKP 601 Query: 3194 HSTRIKTVSDF--GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251 + I+ + VL ++ + G C A N YG D T+ G ++ES Sbjct: 602 TFSWIRNGVNLSNSEEVLKLSNLRVGGDGSIKCVASNFYGTDSAETTLTILEPRGPFIES 661 Query: 3252 LQPDSLAKIRELESLQ 3267 SL+ I + ++ Sbjct: 662 -SSQSLSSINSTDPVR 676 Score = 54.8 bits (126), Expect = 2e-06 Identities = 67/293 (22%), Positives = 124/293 (42%), Gaps = 32/293 (10%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P+P+ W + I + H S L I + DS V+A +A + G + Sbjct: 699 GLPMPVASWKYNSGDITSG-----HVTIQGSALRITKTSNADSGVYACLARSPAGEVTVT 753 Query: 4496 ANLVVEEKR----RQGRGGIVPPS----FTLT-AQNVNVTSGQLVRLDTKVTGT-KPIDV 4545 ++L++ + I S T+T V + + +++ K G KP+ V Sbjct: 754 SHLILIAGSIPVITRSADVIEDQSKFSNLTVTIGTKVTLLASSSIKITCKAIGIPKPV-V 812 Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605 W G+ V P ++++ E L+ L+ D+G C A N+ G A ++++ Sbjct: 813 TWTMRGRPVVPS--DRVMVEKNA--LVFLKILATDTGNVVCTANNARGSDV--ASSLITV 866 Query: 4606 PATKDKPKPQ------TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659 T +P+ Q T+ + P + G + C+ +G P+PT+ W Sbjct: 867 LGTYLRPQNQHCGKVITQLDHQNPVTSKVGASVTALSGVTVTLVCQAIGLPVPTITWTFN 926 Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 K + + + Q++ T T I +A ED GDY C A ++ G+ + + +K+ Sbjct: 927 GKPL--TSHGQVTVTNQSVT--IIKARSEDSGDYVCNATSANGQGSARSVIKI 975 Score = 53.6 bits (123), Expect = 4e-06 Identities = 57/207 (27%), Positives = 84/207 (40%), Gaps = 27/207 (13%) Query: 1997 LEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056 ++ T + P V W GRPV R + AL L A DTG +C A N Sbjct: 798 IKITCKAIGIPKPVVTWTMRGRPVVPSDRVMVEKN----ALVFLKILATDTGNVVCTANN 853 Query: 2057 AVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALT 2116 A G V +S + V G YL ++ K I +L+ Q PV Sbjct: 854 ARGSDVASSLITV---LGTYLRPQNQHCGKVITQLDH-------------QNPVTSKVGA 897 Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176 S+ L G C + I P TI W NG+ + + + T+ ++ I+ + Sbjct: 898 SVTAL-SGVTVTLVC--QAIGLPVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARS 950 Query: 2177 EDSGTYMCKATNKLGEAVNTCTLKVAG 2203 EDSG Y+C AT+ G+ +K+ G Sbjct: 951 EDSGDYVCNATSANGQGSARSVIKIEG 977 Score = 49.6 bits (113), Expect = 6e-05 Identities = 128/623 (20%), Positives = 212/623 (34%), Gaps = 99/623 (15%) Query: 1839 AVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND 1898 AV++ + + L +G C +P P V+W N L R N Sbjct: 16 AVDKVTSLTSSIGNAITLLKGSRVTLVCHATGFPQPI--VQWTRNKVDLTGRMRQLRYNV 73 Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK-ESIIRDSQHESALEKIQY 1957 + + GE SGEY C A N G A + L +++ + IR + ++ Sbjct: 74 THYGVIIDTRFNGELSGEYACLATNKGGFAAVTTDLQIKAPFKPFIRSTWVTGSV----- 128 Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND-PTMRVEWYCN 2016 +K D +V G ++ TE + + PV P +V W N Sbjct: 129 ----GTHKLLKSRDPVIV---TIGDKVETLTGTE------VSIICPVEGLPPPKVTWAKN 175 Query: 2017 GRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLY 2076 G P+ G +F V + A D+G Y C+A N +G+ S V Sbjct: 176 G-PIASGDKFTIARSTDLV-FNSGKASVFDSGRYSCRAVNNLGQDTAYSEVTFREPKAPT 233 Query: 2077 LDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPI 2136 + TLD +K+E F + + + G C E + Sbjct: 234 IMTLD----------DKFEFI---------VNATFTVTIGANVSALRGSSITLTCTAEGL 274 Query: 2137 NDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNT 2196 P + W G ++ G R A + T + DSG Y C ATN G A+ + Sbjct: 275 PVPFVV--WKKGGATLQQGGR----------AFTLSSTESADSGRYDCVATNLKGTAMAS 322 Query: 2197 CTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256 + T H +++ I E ++ F + G + E Sbjct: 323 SAI-----------TIHDKIEKRVAPKILSSKKNLIASENKRL----FYHIIGGNITILE 367 Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316 GK +C + P + ++ NG A+ + + + G +L I E+ G+Y Sbjct: 368 GKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEITAEEQGQYM 423 Query: 2317 VKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRP 2376 K+ N G TV G + + Q + + +P K+P Sbjct: 424 CKSKNIAGEDLETSYTTVV--GPVAPKIQLSNKVYSV-----VDPLKKP----------- 465 Query: 2377 VFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSM 2436 T + + G C G P + W RN + + + + Sbjct: 466 -LTLLVGDTLTTLSGTRTSISCP--ATGFPNPLIRWSRNGESVVPGGHL----KIDGSKL 518 Query: 2437 TISHVRDEDEGVYMCRASNLLGE 2459 +++ + ED GVY C ASN G+ Sbjct: 519 LLTNPQKEDNGVYKCLASNPGGD 541 Score = 49.6 bits (113), Expect = 6e-05 Identities = 49/220 (22%), Positives = 89/220 (40%), Gaps = 28/220 (12%) Query: 3940 SEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAP 3999 S A+T + K+ ++ ++ +L + K+ F I +++E + + +C Sbjct: 322 SSAITIHDKIEKRVAPKILSSKKNLIASENKR--LFYHIIGGNITILEGKDLELQCP--S 377 Query: 4000 VGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDET 4059 +G P V WF NG + + T D A++ + E+ G+Y+C++ N+ G D Sbjct: 378 IGTPKPAVTWFINGSAVTESD--TLKVDPNTGALSIIEITAEEQGQYMCKSKNIAGEDLE 435 Query: 4060 KAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDA 4119 + G + QL + S VV+ K P+ + + D Sbjct: 436 TSYTTVVGP--VAPKIQLSNKVYS-----------------VVDPLK---KPLTLLVGDT 473 Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 +T G C TG P P + W NG ++V G K+ Sbjct: 474 LTTLSGTRTSISCPATGFPNPLIRWSRNGESVVPGGHLKI 513 Score = 49.2 bits (112), Expect = 8e-05 Identities = 65/244 (26%), Positives = 94/244 (38%), Gaps = 34/244 (13%) Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741 R IED+ TV I + + + C+ +G P + W GRP Sbjct: 768 RSADVIEDQSKFS-NLTVTIGTKVTLLASSSIKITCKA--IGIPKPVVTWTMRGRPVVPS 824 Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQL-P 3800 RV + AL I A D G C A N GS ++ IT VL + L P Sbjct: 825 DRVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLIT-------VLGTYLRP 873 Query: 3801 QGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPK 3860 Q K+ I+ + P+ S +T + TV C+ P Sbjct: 874 QNQHCGKV-------ITQLDHQNPVTSKVGASVTALSGVTVT------LVCQAIGLPVPT 920 Query: 3861 LRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920 I W NGK L S H TV + S+ I+ +EDSG+Y+C A + G+ ++ I Sbjct: 921 --ITWTFNGKPLTS-HGQVTVTNQ---SVTIIKARSEDSGDYVCNATSANGQGSARSVIK 974 Query: 3921 CKKL 3924 + L Sbjct: 975 IEGL 978 Score = 47.2 bits (107), Expect = 3e-04 Identities = 68/303 (22%), Positives = 114/303 (37%), Gaps = 45/303 (14%) Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494 + T+S D G Y C A+NL G T H KI+K P Sbjct: 294 AFTLSSTESADSGRYDCVATNLKGTAMASSAI-----------TIHD----KIEKRVAPK 338 Query: 2495 ERRSEEPDREFE-KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553 S++ E K +F ++ G + EG+ E + +G P W+ING + Sbjct: 339 ILSSKKNLIASENKRLFYHIIGGNITILEGKDL--ELQCPSIGTPKPAVTWFINGSAVTE 396 Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRP 2613 + + G L I + A + G YMCK+ N AG + P Sbjct: 397 SDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTT----------VVGP 444 Query: 2614 ESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPN 2673 + +IQL + V + + TT + G + +P Sbjct: 445 VA-PKIQLSNKVYSVVDPLKKPLTLLVGDTLTT--------LSGTRTSISCPATGFPNPL 495 Query: 2674 LKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733 ++ W +NG ++ G LK L + + + +D+G+Y C A+N G+A +T+++ Sbjct: 496 IR--WSRNGESVVPGGHLKIDGS----KLLLTNPQKEDNGVYKCLASNPGGDATATSNMT 549 Query: 2734 IED 2736 D Sbjct: 550 FID 552 Score = 45.2 bits (102), Expect = 0.001 Identities = 53/213 (24%), Positives = 80/213 (37%), Gaps = 31/213 (14%) Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703 FT + + + G + L E P + W K G TL G R + Sbjct: 249 FTVTIGANVSALRGSSITLTCTAEGLPVPF--VVWKKGGATLQQGGR----------AFT 296 Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXX 2763 ++S + DSG Y C ATNL G A+++++I I D+ + + + P L L Sbjct: 297 LSSTESADSGRYDCVATNLKGTAMASSAITIHDK---IEKRVAPKILSSKKNLIASENKR 353 Query: 2764 XXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPS-RDPTLKIEWFFNNKPLPSGTRY 2822 NI EG ++ +C PS P + WF N + Sbjct: 354 LFYHIIG----------GNITILEGKDLELQC---PSIGTPKPAVTWFINGSAVTESDTL 400 Query: 2823 KSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855 K D + +L I E+ G Y CK+ N G Sbjct: 401 KV--DPNTGALSIIEITAEEQGQYMCKSKNIAG 431 Score = 45.2 bits (102), Expect = 0.001 Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 29/204 (14%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 V W GRPV S R+ N AL + D G+ C A NA G S+ +T++ Sbjct: 812 VTWTMRGRPVVPSDRVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLITVL 867 Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062 + ++QH G + I L+ + + + V L G + Q+ Sbjct: 868 GTY-LRPQNQHCGKV--ITQLDHQNPVTSKVGASVTA---------LSGVTVTLVCQAIG 915 Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122 T+ W FNGK +TS ++ + ++ I R+EDSG Y A + Sbjct: 916 LPVP---------TITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATS 962 Query: 1123 AAGEAQLSASMTVETRSSIDTSSI 1146 A G+ + + +E S +S+ Sbjct: 963 ANGQGSARSVIKIEGLLSYKKNSV 986 Score = 44.0 bits (99), Expect = 0.003 Identities = 77/308 (25%), Positives = 117/308 (37%), Gaps = 60/308 (19%) Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539 L I+ T DSG Y C A + GE T+ + I++ +P I + A Sbjct: 726 LRITKTSNADSGVYACLARSPAGEVTVTSHL-------ILIAGSIP-----VITRSA--- 770 Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599 D + +++ N T + + L +SS C+ I + V W G+P Sbjct: 771 ------DVIEDQSKFSNLT--VTIGTKVTLLASSSIKITCKAIGIPKPV--VTWTMRGRP 820 Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659 ++ RV + V L+I D G C A N G S + V G L P Sbjct: 821 VVPSDRVM-VEKNALVFLKI---LATDTGNVVCTANNARGSDVASSLITVLGTY---LRP 873 Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRV 3719 Q H + IT D + NP T ++ ++ G V C+ Sbjct: 874 Q-----------------NQHCGKVITQLDHQ-NP--VTSKVGASVTALSGVTVTLVCQA 913 Query: 3720 EPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT--NKWG 3777 +G P I W NG+P + +V N ++ I + D+G+Y C AT N G Sbjct: 914 --IGLPVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQG 967 Query: 3778 SATTTAKI 3785 SA + KI Sbjct: 968 SARSVIKI 975 Score = 43.2 bits (97), Expect = 0.005 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Query: 3990 TTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCR 4049 T CQ +G P + W FNGKPL + T ++ EDSG+Y+C Sbjct: 906 TVTLVCQA--IGLPVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCN 959 Query: 4050 ATNLYGMDETKAVIKTTG 4067 AT+ G ++VIK G Sbjct: 960 ATSANGQGSARSVIKIEG 977 Score = 41.1 bits (92), Expect = 0.021 Identities = 41/139 (29%), Positives = 59/139 (42%), Gaps = 19/139 (13%) Query: 4041 EDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQ 4100 E SGEY C ATN G A + T D Q+ K IR + V + Sbjct: 87 ELSGEYACLATNKGGF----AAVTT--------DLQIKAPFKPF--IRSTWVTGSVGTHK 132 Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 ++ K+R PV V++ D V G C V G P P+V W NG I +G ++ + Sbjct: 133 LL---KSR-DPVIVTIGDKVETLTGTEVSIICPVEGLPPPKVTWAKNG-PIASGDKFTIA 187 Query: 4161 YDGMYHFDIPKTRQYDTGK 4179 F+ K +D+G+ Sbjct: 188 RSTDLVFNSGKASVFDSGR 206 Score = 41.1 bits (92), Expect = 0.021 Identities = 67/302 (22%), Positives = 117/302 (38%), Gaps = 50/302 (16%) Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828 AL + + DSG Y C A + GE +S L + + S+ + ++ + ED S Sbjct: 725 ALRITKTSNADSGVYACLARSPAGEVTVTSHLILIA-GSIPVITRSADVI------EDQS 777 Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888 ++ ++ V + T++ L S C+ P P V W G+ + Sbjct: 778 KFS---NLTVTIG------TKVT----LLASSSIKITCKAIGIPKPV--VTWTMRGRPVV 822 Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948 R + AL L + D+G C A N G V+S + V + +R Q+ Sbjct: 823 PSDRVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLITVLG--TYLRP-QN 875 Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008 + + I L+ + V A VT V + + P Sbjct: 876 QHCGKVITQLDHQNPVTSKV-----------------GASVTALSGVTVTLVCQAIGLPV 918 Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068 + W NG+P+ + T ++ I+ A +ED+G Y+C AT+A G+ S +K Sbjct: 919 PTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSVIK 974 Query: 2069 VD 2070 ++ Sbjct: 975 IE 976 Score = 40.3 bits (90), Expect = 0.037 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 6/94 (6%) Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704 SVTA+ G + + +G P I W NG+ + + + T + S+ ++ + Sbjct: 898 SVTALSGVTVTLVC--QAIGLPVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSE 951 Query: 705 DSGEYTCRAVSATGVAETKAVLHVTPRATIERTS 738 DSG+Y C A SA G ++V+ + + ++ S Sbjct: 952 DSGDYVCNATSANGQGSARSVIKIEGLLSYKKNS 985 Score = 39.9 bits (89), Expect = 0.049 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 P I W FN KPL S + T+ S+ I EDSG Y C AT++ G + Sbjct: 917 PVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSV 972 Query: 2863 LRCTG 2867 ++ G Sbjct: 973 IKIEG 977 Score = 38.3 bits (85), Expect = 0.15 Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 20/175 (11%) Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140 V+ W G+ + S R+ V +V L+IL T D+G C A N G S + Sbjct: 811 VVTWTMRGRPVVPSDRVM-VEKNALVFLKILAT---DTGNVVCTANNARGSDVASSLITV 866 Query: 3141 VD---KSKGQK-PRFTTHI--QNIEGLKDGQS----AHFECTVV--PVDDPDMKIEWYHN 3188 + + + Q + T + QN K G S + T+V + P I W N Sbjct: 867 LGTYLRPQNQHCGKVITQLDHQNPVTSKVGASVTALSGVTVTLVCQAIGLPVPTITWTFN 926 Query: 3189 GQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243 G+P+ ++ TV++ ++ ++ DSG+YVC A + G+ R+ I G Sbjct: 927 GKPLTSHGQV-TVTNQSVTIIK---ARSEDSGDYVCNATSANGQGSARSVIKIEG 977 Score = 37.9 bits (84), Expect = 0.20 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%) Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704 +V+A+ G I E G P + W K G +++ R + + S Sbjct: 256 NVSALRGSSITLTCTAE--GLPVPFVVWKKGGATLQQGGR----------AFTLSSTESA 303 Query: 705 DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEE 764 DSG Y C A + G A + + + + IE+ P+ L + L Sbjct: 304 DSGRYDCVATNLKGTAMASSAITIHDK--IEKRVA-PKILSSKKNLI------------- 347 Query: 765 QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824 + + F + + EG++ E Q + P V W+ +G +T S + N Sbjct: 348 ASENKRLFYHIIGGNITILEGKD--LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPN 405 Query: 825 FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858 G +L+I+ + AE+ G Y ++ N GE + T+ Sbjct: 406 TG--ALSIIEITAEEQGQYMCKSKNIAGEDLETS 437 Score = 37.9 bits (84), Expect = 0.20 Identities = 44/211 (20%), Positives = 79/211 (37%), Gaps = 31/211 (14%) Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027 D+ + I ++ +L+ + K C+ +G P V W G+P++ +R + Sbjct: 775 DQSKFSNLTVTIGTKVTLLASSSIKITCKA--IGIPKPVVTWTMRGRPVVPSDRVMVEKN 832 Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKI 4087 A+ F + D+G +C A N G D ++I G Y +H + I Sbjct: 833 ----ALVFLKILATDTGNVVCTANNARGSDVASSLITVLG----TYLRPQNQHCGKV--I 882 Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147 +++ PV + +VT G C+ G P P + W N Sbjct: 883 TQLDHQ----------------NPVTSKVGASVTALSGVTVTLVCQAIGLPVPTITWTFN 926 Query: 4148 GNTIVNGSRYKLTYDGMYHFDIPKTRQYDTG 4178 G + + + +T + I K R D+G Sbjct: 927 GKPLTSHGQVTVTNQSV---TIIKARSEDSG 954 Score = 37.5 bits (83), Expect = 0.26 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 4/98 (4%) Query: 905 STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964 S K F I I+I EG E + IG V W +G V S + N Sbjct: 349 SENKRLFYHIIGGNITILEG--KDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNT 406 Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 G AL+I +T + G Y C++ N G+ ++ T+V Sbjct: 407 G--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVV 442 Score = 37.1 bits (82), Expect = 0.35 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 2/59 (3%) Query: 942 RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000 +V W K+G P+ + + T + V + K+ +V D+G Y+CRA N +GQ T + +T Sbjct: 169 KVTWAKNG-PIASGDKFTIARSTDLVFNSGKA-SVFDSGRYSCRAVNNLGQDTAYSEVT 225 Score = 36.7 bits (81), Expect = 0.46 Identities = 47/180 (26%), Positives = 72/180 (40%), Gaps = 28/180 (15%) Query: 3075 TGDQSMVIEWFYNGKTIEASHR-IR-TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132 TG +++W N + R +R V +G+++ + SG Y+C ATNK G A Sbjct: 46 TGFPQPIVQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGEL--SGEYACLATNKGGFA 103 Query: 3133 EISVKLEC------------VDKS-------KGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173 ++ L+ V S K + P T +E L G C V Sbjct: 104 AVTTDLQIKAPFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKVETLT-GTEVSIICPV 162 Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233 + P K+ W NG P+ + T++ +V + DSG Y CRA N G+D Sbjct: 163 EGLPPP--KVTWAKNG-PIASGDKF-TIARSTDLVFNSGKASVFDSGRYSCRAVNNLGQD 218 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 6/72 (8%) Query: 90 KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149 K K G P PVV+WT + P+V ++ + N +L+ +I D G CTA Sbjct: 799 KITCKAIGIPKPVVTWTMRGRPVVPSDRVMVEKN------ALVFLKILATDTGNVVCTAN 852 Query: 150 NQYGEAICSVYI 161 N G + S I Sbjct: 853 NARGSDVASSLI 864 Score = 36.3 bits (80), Expect = 0.61 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 2/55 (3%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718 G P K+ W KNG I + +FT I R + + ++ DSG Y+CRAV+ G Sbjct: 164 GLPPPKVTWAKNGP-IASGDKFT-IARSTDLVFNSGKASVFDSGRYSCRAVNNLG 216 Score = 35.9 bits (79), Expect = 0.80 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 8/115 (6%) Query: 3945 QMEATIKKYTSEVYLTED-DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPV-GD 4002 Q++A K + ++T + + K + P VT +L E + + PV G Sbjct: 110 QIKAPFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKVETLTGTEVSI----ICPVEGL 165 Query: 4003 PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057 P KV W NG P+ ++FT V N G DSG Y CRA N G D Sbjct: 166 PPPKVTWAKNG-PIASGDKFTIARSTDLV-FNSGKASVFDSGRYSCRAVNNLGQD 218 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 4/60 (6%) Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 I W NG LT+ ++ T +++I R++DSG Y C AT+ G+ + + IKIE Sbjct: 921 ITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSVIKIE 976 Score = 35.5 bits (78), Expect = 1.1 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 7/86 (8%) Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433 Q PV ++ ++ + G T C+ I + PT + W N K + ++T T+ Sbjct: 888 QNPVTSKVGASVTALS-GVTVTLVCQAIGLPVPT--ITWTFNGKPLTSHGQVTVTNQ--- 941 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459 S+TI R ED G Y+C A++ G+ Sbjct: 942 -SVTIIKARSEDSGDYVCNATSANGQ 966 Score = 35.5 bits (78), Expect = 1.1 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 4/61 (6%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 + W NGKPL + +V T+ + I++ D+G Y C AT+ +G+ + ++++ Sbjct: 921 ITWTFNGKPLTSHGQV-TVTNQSVTIIK---ARSEDSGDYVCNATSANGQGSARSVIKIE 976 Query: 3651 G 3651 G Sbjct: 977 G 977 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 3/85 (3%) Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155 +T V E +++ + V++ VT+ + C+ G PKP V W + G +V Sbjct: 766 ITRSADVIEDQSKFSNLTVTIGTKVTLLASSSIKITCKAIGIPKPVVTWTMRGRPVVPSD 825 Query: 4156 RYKLTYDGMYHFDIPKTRQYDTGKI 4180 R + + + I T DTG + Sbjct: 826 RVMVEKNALVFLKILAT---DTGNV 847 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 2/66 (3%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 G P P+V WTR K L +RYN V ++ + GEY C A N+ G A Sbjct: 47 GFPQPIVQWTRNKVDLTG-RMRQLRYNVTHYGV-IIDTRFNGELSGEYACLATNKGGFAA 104 Query: 157 CSVYIQ 162 + +Q Sbjct: 105 VTTDLQ 110 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Query: 3447 TDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVT 3506 T PN + W NG+S+ G + G +L +P ED+G Y C A N G+A Sbjct: 489 TGFPNPLIRWSRNGESVVPGGHLKID---GSKLLLTNPQ-KEDNGVYKCLASNPGGDATA 544 Query: 3507 TASM 3510 T++M Sbjct: 545 TSNM 548 Score = 34.7 bits (76), Expect = 1.9 Identities = 17/63 (26%), Positives = 35/63 (55%), Gaps = 4/63 (6%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P + W +G+P+T+ ++T + N S+ I+ R+ED+G Y A + G+ + + Sbjct: 917 PVPTITWTFNGKPLTSHGQVT-VTN---QSVTIIKARSEDSGDYVCNATSANGQGSARSV 972 Query: 860 IRV 862 I++ Sbjct: 973 IKI 975 Score = 32.7 bits (71), Expect = 7.5 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Query: 4115 SLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTR 4173 S+ +A+T+ +G C TG P+P V W N + G +L Y+ ++ I TR Sbjct: 26 SIGNAITLLKGSRVTLVCHATGFPQPIVQWTRN-KVDLTGRMRQLRYNVTHYGVIIDTR 83 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 4/61 (6%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862 P I W N + + G K D S L +T+ +ED+G+Y C A+N G AT + + Sbjct: 492 PNPLIRWSRNGESVVPGGHLKI--DGS--KLLLTNPQKEDNGVYKCLASNPGGDATATSN 547 Query: 2863 L 2863 + Sbjct: 548 M 548 >SB_29237| Best HMM Match : I-set (HMM E-Value=0) Length = 869 Score = 86.2 bits (204), Expect = 6e-16 Identities = 83/285 (29%), Positives = 114/285 (40%), Gaps = 30/285 (10%) Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586 +G L++L K G + V W K+G + P N + G L DSG Y C Sbjct: 148 AGILIQLRCKCNGMPKVTVEWKKDGVTIIP---NSEIVASGN-RLNFENPKVADSGNYTC 203 Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646 +A N G V PA K A+ P + P D I G I C Sbjct: 204 IAQNFLG--------VRESPAFK----MSVIVASVPVFQVRP-SDTIAVVGDTITLYCSA 250 Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 G P P + WY ++S AD +L+IS D G YKCVA N V Sbjct: 251 TGTPKPDISWYLETSTDPLKNSSKISANADG-SLKISNIEKSDFGTYKCVASNIMANYAV 309 Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW-LREGALIPETP 4765 A++ + P P R I+ E QP F + KPTI W L +G +P Sbjct: 310 EAEVGEAFIGEMVLAP---PTRYIL--EKQPFTFACDVKGLPKPTISWSLADGKSLPAKY 364 Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 D + NN T ED+G FTC A+ AG+ + ++++ Sbjct: 365 DMKGTALRNN------KTAMEDSGNFTCTASNTAGKKSQTVQIII 403 Score = 74.5 bits (175), Expect = 2e-12 Identities = 82/329 (24%), Positives = 137/329 (41%), Gaps = 54/329 (16%) Query: 250 VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF--KNGQRLI 307 V+ S S+ S P +P ++ G +G P+P ++W+ + L Sbjct: 211 VRESPAFKMSVIVASVPVFQVRPSDTIAVVGDTITLYCSATGTPKPDISWYLETSTDPLK 270 Query: 308 NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367 NS+K I+ + +L++ N +KSD G Y +A N + + Y AVE+ Sbjct: 271 NSSK---ISANADGSLKISNIEKSDFGTYKCVASN-----IMANY-AVEA---------- 311 Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427 E E I E LAP R + E + F C V G P P ++W + Sbjct: 312 ----------EVGEAF-IGEMVLAPP------TRYILEKQPFTFACDVKGLPKPTISWSL 354 Query: 428 ND-RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486 D + + Y+ K AL + DSG TC A N +G+ + ++ + + Sbjct: 355 ADGKSLPAKYDMK-------GTALRNNKTAMEDSGNFTCTASNTAGKKSQTVQIIISQP- 406 Query: 487 QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546 P E + EG VVL A G P P++ WQ++ + ++ + I++ G Sbjct: 407 ----PVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKLIWQRNQIDVVQDGNHEINSRG--- 459 Query: 547 TLDIPRAKASDAAWYQCTAQNVAGSTATR 575 L I + D Y+C A+++ G AT+ Sbjct: 460 YLVIRKVAPRDGGLYECIARHLGGWEATK 488 Score = 68.9 bits (161), Expect = 9e-11 Identities = 70/288 (24%), Positives = 109/288 (37%), Gaps = 32/288 (11%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 P F + + G + L TGT D+ W P + + + +L I Sbjct: 227 PVFQVRPSDTIAVVGDTITLYCSATGTPKPDISWYLE-TSTDPLKNSSKISANADGSLKI 285 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633 D G Y+CVA N +AE + + APP + Sbjct: 286 SNIEKSDFGTYKCVASNIMANYAVEAEVGEAFIG---------EMVLAPPT-------RY 329 Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 + E Q F+C + G P PT+ W D P+KY M TA LR ++ ED G++ Sbjct: 330 ILEKQPFTFACDVKGLPKPTISWSLADGKSLPAKY-DMKGTA----LRNNKTAMEDSGNF 384 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTI 4752 C A N+AG+ + ++ ++QP P LT +D+ EG K P + Sbjct: 385 TCTASNTAGKKSQTVQIIISQP------PVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKL 438 Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 W R + + + ++ G L+I D G + C A G Sbjct: 439 IWQRNQIDVVQDGNHEINSRG---YLVIRKVAPRDGGLYECIARHLGG 483 Score = 68.1 bits (159), Expect = 2e-10 Identities = 76/297 (25%), Positives = 113/297 (38%), Gaps = 23/297 (7%) Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVT-GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 +F Q+ V GQ V L G + I W +G K++P R I+ +DG+ L I Sbjct: 37 TFLAQPQDTAVVLGQAVTLKCVAQFGDRRIRYSWTLDGNKIRPTDR-VIVNQDGS--LSI 93 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633 + +D+G+Y CVA + R E + K A++P + + P Sbjct: 94 IATQKEDAGEYICVA-KARMNKRNYVESSRAAALEVQSICEAAKIASSPSQSLFP----- 147 Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 G I+ CK G P TV+W K I P+ A L D G+Y Sbjct: 148 --AGILIQLRCKCNGMPKVTVEWKKDGVTIIPNSEI----VASGNRLNFENPKVADSGNY 201 Query: 4694 KCVAYNSAG-RVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPT 4751 C+A N G R + A K+ V ++P D + G T KP Sbjct: 202 TCIAQNFLGVRESPAFKMSVI----VASVPVFQVRPSDTIAVVGDTITLYCSATGTPKPD 257 Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 I W E + P + I + L I N + D GT+ C A+ A++ Sbjct: 258 ISWYLETSTDP-LKNSSKISANADGSLKISNIEKSDFGTYKCVASNIMANYAVEAEV 313 Score = 64.9 bits (151), Expect = 2e-09 Identities = 86/350 (24%), Positives = 139/350 (39%), Gaps = 49/350 (14%) Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436 E + T T + K+QT + ++ S+PP+ T++ + + E + + G Sbjct: 379 EDSGNFTCTASNTAGKKSQTVQIII------SQPPVLTEEPKDMQAMEGLKVVLKCAAKG 432 Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG-TAKCS 4495 P P + W R + + H +++ L+IR+V D ++ +A + GG A + Sbjct: 433 VPPPKLIWQRNQIDVVQDGN---HEINSRGYLVIRKVAPRDGGLYECIARHLGGWEATKT 489 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555 AN+ V + V F L G ++ G P+ + W K G Sbjct: 490 ANVSVMAAVKLADYHQVHHKFDL---------GSKGKIYCTFKGHPPVKIVWAKVGGAE- 539 Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615 +K E DG TL+I + D+G Y C +N G + A VS+ PK + Sbjct: 540 ---LSKKTEIDGD-TLIIKDLQMSDAGMYSCTGMN--GFSNYTAYVNVSVFV---YPKFE 590 Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK----GDKLIKPSKYFQM 4671 K N ++ +I C G P P + W K GD L K ++ Q Sbjct: 591 LKPKNTTAMAMD-----------SIWLHCNASGYPKPKISWGKEQQGGDNLDK-ERFIQF 638 Query: 4672 SRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721 + +L I EDEG Y C+A N A + LKV + A+ L Sbjct: 639 ----ENGSLLIKNIKLEDEGRYYCIAGNLADFKQITISLKVVRNSPAEAL 684 Score = 58.8 bits (136), Expect = 1e-07 Identities = 47/181 (25%), Positives = 78/181 (43%), Gaps = 12/181 (6%) Query: 394 FVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452 F+ QD V G+ C G +W ++ +IR +++VN+ G+ +++ Sbjct: 38 FLAQPQDTAVVLGQAVTLKCVAQFGDRRIRYSWTLDGNKIRP--TDRVIVNQDGSLSIIA 95 Query: 453 TNVTLSDSGVVTCVARNKSGETAF--QCRLNVIEKEQVV-APKFVERFSTLNVREGEPVV 509 T D+G CVA+ + + + R +E + + A K S G + Sbjct: 96 TQK--EDAGEYICVAKARMNKRNYVESSRAAALEVQSICEAAKIASSPSQSLFPAGILIQ 153 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 L + G P + W+KDGV IIPN E+ + L+ K +D+ Y C AQN Sbjct: 154 LRCKCNGMPKVTVEWKKDGVTIIPNSEI----VASGNRLNFENPKVADSGNYTCIAQNFL 209 Query: 570 G 570 G Sbjct: 210 G 210 Score = 57.6 bits (133), Expect = 2e-07 Identities = 48/191 (25%), Positives = 71/191 (37%), Gaps = 14/191 (7%) Query: 389 ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448 A P F D G C TG P P+++W++ + KI N G Sbjct: 224 ASVPVFQVRPSDTIAVVGDTITLYCSATGTPKPDISWYLETSTDPLKNSSKISANADG-- 281 Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRL-NVIEKEQVVAPKFVERFSTLNVREGEP 507 +L I+N+ SD G CVA N A + + E V+AP T + E +P Sbjct: 282 SLKISNIEKSDFGTYKCVASNIMANYAVEAEVGEAFIGEMVLAP------PTRYILEKQP 335 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 G P P I+W + L D + L + D+ + CTA N Sbjct: 336 FTFACDVKGLPKPTISWS-----LADGKSLPAKYDMKGTALRNNKTAMEDSGNFTCTASN 390 Query: 568 VAGSTATRARL 578 AG + ++ Sbjct: 391 TAGKKSQTVQI 401 Score = 53.2 bits (122), Expect = 5e-06 Identities = 49/176 (27%), Positives = 68/176 (38%), Gaps = 12/176 (6%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P + +D EG C G P P++ W N + D NH+I N G L+ Sbjct: 407 PVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKLIWQRNQIDVVQDGNHEI--NSRGY--LV 462 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511 I V D G+ C+AR+ G A + NV V + + ++ G + Sbjct: 463 IRKVAPRDGGLYECIARHLGGWEATKTA-NVSVMAAVKLADYHQVHHKFDL--GSKGKIY 519 Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 G P +I W K G EL T+ TL I + SDA Y CT N Sbjct: 520 CTFKGHPPVKIVWAKVG-----GAELSKKTEIDGDTLIIKDLQMSDAGMYSCTGMN 570 Score = 52.8 bits (121), Expect = 7e-06 Identities = 55/274 (20%), Positives = 105/274 (38%), Gaps = 19/274 (6%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP+ + K+ + +G + +G P P + W R + +V+ + + Sbjct: 406 PPVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKLIWQRNQIDVVQDGNHEINSRGY----- 460 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190 L+I+++ P D G Y C AR+ G + + Y V + + Sbjct: 461 LVIRKVAPRDGGLYECIARHLGG------WEATKTANVSVMAAVKLADYHQVHHKFDLGS 514 Query: 191 YGTQGYTTEQSRQTQKVAYTN--GTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES 248 G + Y T + K+ + G + S + DT +++++ ++ G + Sbjct: 515 KG-KIYCTFKGHPPVKIVWAKVGGAELSKKTEIDGDTL---IIKDLQMSDAGMYSCTGMN 570 Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308 T ++ PK KP+N+ SG P+P+++W K Q N Sbjct: 571 GFSNYTAYV-NVSVFVYPKFELKPKNTTAMAMDSIWLHCNASGYPKPKISWGKEQQGGDN 629 Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342 +K I N + L ++N + D G Y +A N Sbjct: 630 LDKERFIQFENGSLL-IKNIKLEDEGRYYCIAGN 662 Score = 45.2 bits (102), Expect = 0.001 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 267 KIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326 KIA P S G Q + + +G P+ V W K+G +I ++ EI+ + N L Sbjct: 136 KIASSPSQSLFPAGILIQLRCKCNGMPKVTVEWKKDGVTIIPNS--EIVASGNR--LNFE 191 Query: 327 NTQKSDSGHYTLLAEN 342 N + +DSG+YT +A+N Sbjct: 192 NPKVADSGNYTCIAQN 207 Score = 40.7 bits (91), Expect = 0.028 Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 10/128 (7%) Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503 E L+I ++ +SD+G+ +C N G + + +NV V PKF + Sbjct: 545 EIDGDTLIIKDLQMSDAGMYSCTGMN--GFSNYTAYVNV---SVFVYPKFELKPKNTTAM 599 Query: 504 EGEPVVLNARAVGTPTPRITWQKD--GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561 + + L+ A G P P+I+W K+ G + + E I + G +L I K D Y Sbjct: 600 AMDSIWLHCNASGYPKPKISWGKEQQGGDNL-DKERFIQFENG--SLLIKNIKLEDEGRY 656 Query: 562 QCTAQNVA 569 C A N+A Sbjct: 657 YCIAGNLA 664 Score = 39.1 bits (87), Expect = 0.086 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 6/110 (5%) Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765 +I+Q PV T KD++ E + V PKL W RN + + ++ Sbjct: 402 IISQPPVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKL--IWQRNQIDVVQDGN-HEINSR 458 Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHE 1815 GY+ + + V P D G Y C A LG + T V A+++L H+ Sbjct: 459 GYLVI--RKVAPRDGGLYECIA-RHLGGWEATKTANVSVMAAVKLADYHQ 505 Score = 36.7 bits (81), Expect = 0.46 Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 16/156 (10%) Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134 G + +EW +G TI + I A G L K DSG Y+C A N G E Sbjct: 160 GMPKVTVEWKKDGVTIIPNSEI---VASGNR-LNFENPKVADSGNYTCIAQNFLGVRESP 215 Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWY--HNGQPM 3192 + K+ + S P F + + G + C+ PD I WY + P+ Sbjct: 216 AFKMSVIVAS---VPVFQVRPSDTIAVV-GDTITLYCSATGTPKPD--ISWYLETSTDPL 269 Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228 ++S++I +D L I+ + D G Y C A N Sbjct: 270 KNSSKISANADGS---LKISNIEKSDFGTYKCVASN 302 Score = 36.7 bits (81), Expect = 0.46 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792 G PK+ VEW ++GV I ++ + + LN + DSG YTC A N LG Sbjct: 160 GMPKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIAQNFLG 210 Score = 35.9 bits (79), Expect = 0.80 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 4/59 (6%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 P + +EW K+GVT+ + + ++ + L+ + + DSG YTC A N LG S A Sbjct: 162 PKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIAQNFLGVRESPA 216 Score = 35.5 bits (78), Expect = 1.1 Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 2/78 (2%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C +G P P+++W ++Q D+ + + + + N +L+I N+ L D G C+A N + Sbjct: 608 CNASGYPKPKISWG-KEQQGGDNLDKERFI-QFENGSLLIKNIKLEDEGRYYCIAGNLAD 665 Query: 473 ETAFQCRLNVIEKEQVVA 490 L V+ A Sbjct: 666 FKQITISLKVVRNSPAEA 683 Score = 35.1 bits (77), Expect = 1.4 Identities = 23/59 (38%), Positives = 30/59 (50%), Gaps = 4/59 (6%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858 P + VEW KDG I +S I + N LN + + D+G+YT A N LG S A Sbjct: 162 PKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIAQNFLGVRESPA 216 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/100 (29%), Positives = 41/100 (41%), Gaps = 7/100 (7%) Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768 E P F C V+ + PT I W A G + D AL + D+G + Sbjct: 332 EKQPFTFACDVKGLPKPT--ISW-----SLADGKSLPAKYDMKGTALRNNKTAMEDSGNF 384 Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808 TC A+N G + T +I S + E + Q M G K+ Sbjct: 385 TCTASNTAGKKSQTVQIIISQPPVLTEEPKDMQAMEGLKV 424 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%) Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918 GQ+ +C + + D +R W +G ++ R + D +L I+ ED+GEY Sbjct: 50 GQAVTLKC-VAQFGDRRIRYSWTLDGNKIRPTDRVIVNQD---GSLSIIATQKEDAGEYI 105 Query: 1919 C--KAINNLGQAVSSIRLNVQSKESI 1942 C KA N V S R +SI Sbjct: 106 CVAKARMNKRNYVESSRAAALEVQSI 131 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 654 IHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA 713 I + R + G P + +EW K+G +I +S + L+ + + DSG YTC A Sbjct: 150 ILIQLRCKCNGMPKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIA 205 Query: 714 VSATGVAETKA 724 + GV E+ A Sbjct: 206 QNFLGVRESPA 216 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991 G + VEW KDG + +S I N L ++ V D+G+YTC A N +G Sbjct: 160 GMPKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIAQNFLG 210 Score = 33.9 bits (74), Expect = 3.2 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 2/55 (3%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT--IVNGSRYKLTYDG 4163 PVF P G+ C TG PKP + W L +T + N S+ DG Sbjct: 227 PVFQVRPSDTIAVVGDTITLYCSATGTPKPDISWYLETSTDPLKNSSKISANADG 281 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 GQ+ +C V D ++ W +G +R + R+ D L I TQ D+GEY+ Sbjct: 50 GQAVTLKC-VAQFGDRRIRYSWTLDGNKIRPTDRVIVNQDGS---LSIIATQKEDAGEYI 105 Query: 3224 CRA 3226 C A Sbjct: 106 CVA 108 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 5/90 (5%) Query: 3276 TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH 3335 T S F+ Q QD T +V GQ+ + + D ++ W +G K+ R Sbjct: 30 TESQSKITFLAQPQD-TAVVLGQAVTLKC-VAQFGDRRIRYSWTLDGNKIRPTDRVIVNQ 87 Query: 3336 DFGIVILDILYCYEENSGEYECVATNKLGR 3365 D L I+ +E++GEY CVA ++ + Sbjct: 88 DGS---LSIIATQKEDAGEYICVAKARMNK 114 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/122 (23%), Positives = 49/122 (40%), Gaps = 8/122 (6%) Query: 1836 VEVAVNQAPRFITQLNGPTK-LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894 VE V +A L PT+ + E Q + C ++ P P + W L G Sbjct: 309 VEAEVGEAFIGEMVLAPPTRYILEKQPFTFACDVKGLPKPT--ISWS-----LADGKSLP 361 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954 D AL EDSG +TC A N G+ ++++ + + + + A+E Sbjct: 362 AKYDMKGTALRNNKTAMEDSGNFTCTASNTAGKKSQTVQIIISQPPVLTEEPKDMQAMEG 421 Query: 1955 IQ 1956 ++ Sbjct: 422 LK 423 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 7/95 (7%) Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852 F C+V+ PT I W L G + +D +L T EDSG +TC A+N Sbjct: 338 FACDVKGLPKPT--ISW-----SLADGKSLPAKYDMKGTALRNNKTAMEDSGNFTCTASN 390 Query: 2853 SKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAV 2887 + G + + + + + + + Q GL+ V Sbjct: 391 TAGKKSQTVQIIISQPPVLTEEPKDMQAMEGLKVV 425 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183 G +C V D + W +G KIR R D +L I+ T ED+G Y+ Sbjct: 50 GQAVTLKC-VAQFGDRRIRYSWTLDGNKIRPTDRVIVNQDG---SLSIIATQKEDAGEYI 105 Query: 2184 CKATNKLGE 2192 C A ++ + Sbjct: 106 CVAKARMNK 114 Score = 32.3 bits (70), Expect = 9.9 Identities = 17/51 (33%), Positives = 24/51 (47%) Query: 2684 TLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +L G L + +D L N +DSG +TC A+N G+ T I I Sbjct: 353 SLADGKSLPAKYDMKGTALRNNKTAMEDSGNFTCTASNTAGKKSQTVQIII 403 >SB_1528| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2409 Score = 85.8 bits (203), Expect = 8e-16 Identities = 83/306 (27%), Positives = 125/306 (40%), Gaps = 29/306 (9%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN----KILEEDGTY 4569 P TL ++ + Q L + TG+ +YWLK+G+ V D + + + +G Sbjct: 792 PVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDL 851 Query: 4570 TLL--ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627 T L I + DSG Y+CVA NSAG+A S AT + ++K P Sbjct: 852 TFLRVINKKRKSDSGVYQCVAENSAGKA-------FSKNATLEVGVLRSKFRAEP----- 899 Query: 4628 PLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686 KD + G C G+P PTV W K K P + L IS A Sbjct: 900 --KDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDGV--RIQKVSPGNLVISIAQ 955 Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746 D G Y+CVA N+ GR + VT + ++ P + I V GQ F Q Sbjct: 956 KADMGTYQCVAANAVGR-RKSRVATVTIKESPTTALSIDP-KQITVISGQSTSFSCQYRD 1013 Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806 + ++W ++G +P + L + + D G + C +G + SA Sbjct: 1014 GPQAAVRWQKKGGDLP----LNRYVTTQSGELQLSSIQPGDAGEYVCSVPLESGVLSVSA 1069 Query: 4807 KLVVKS 4812 KL V++ Sbjct: 1070 KLEVQN 1075 Score = 74.1 bits (174), Expect = 2e-12 Identities = 76/284 (26%), Positives = 118/284 (41%), Gaps = 34/284 (11%) Query: 4436 GEPLPLIKWYRENFPIK-NSPDFQIHTFSTKS-----ILIIRQVFVEDSAVFAAVAENRG 4489 G P P I W ++ + + D + F + + +I + DS V+ VAEN Sbjct: 817 GSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSA 876 Query: 4490 GTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID-VYWL 4548 G A S N +E G++ F +++++T G L +P V WL Sbjct: 877 GKA-FSKNATLEV-------GVLRSKFRAEPKDLSITIGNRAILKCNPPKGRPAPTVTWL 928 Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608 KN K PD +++ L+I A D G Y+CVA N+ G + V Sbjct: 929 KNTKAYVPD--GVRIQKVSPGNLVISIAQKADMGTYQCVAANAVGRRKSRVATVTI---- 982 Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668 K P T + P +I V GQ+ FSC+ P V+W K + ++Y Sbjct: 983 --KESPTTALSIDPKQIT-------VISGQSTSFSCQYRDGPQAAVRWQKKGGDLPLNRY 1033 Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 T L++S P D G+Y C +G ++V+AKL+V Sbjct: 1034 V----TTQSGELQLSSIQPGDAGEYVCSVPLESGVLSVSAKLEV 1073 Score = 65.7 bits (153), Expect = 9e-10 Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 11/173 (6%) Query: 409 TRFDCRVTGRPYPEVTWFINDRQI----RDDYNHK-ILVNESGNHALMITNVTLSDSGVV 463 T CR TG P P++ W + R + D N + I+ N +I SDSGV Sbjct: 809 TDLRCRATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVY 868 Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR-AVGTPTPRI 522 CVA N +G+ AF N + V+ KF L++ G +L G P P + Sbjct: 869 QCVAENSAGK-AFS--KNATLEVGVLRSKFRAEPKDLSITIGNRAILKCNPPKGRPAPTV 925 Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575 TW K+ +P+ +RI L I A+ +D YQC A N G +R Sbjct: 926 TWLKNTKAYVPD-GVRIQ-KVSPGNLVISIAQKADMGTYQCVAANAVGRRKSR 976 Score = 58.0 bits (134), Expect = 2e-07 Identities = 48/190 (25%), Positives = 79/190 (41%), Gaps = 14/190 (7%) Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI------KPSKYFQMSR 4673 N P I D + + Q + C+ G P P + W K +++ ++ F M Sbjct: 789 NTKPVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPN 848 Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733 + I++ D G Y+CVA NSAG+ +K + + P +D+ + Sbjct: 849 GDLTFLRVINKKRKSDSGVYQCVAENSAGK--AFSKNATLEVGVLRSKFRAEP-KDLSIT 905 Query: 4734 EGQPAQFK-TQITSKIKPTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791 G A K + PT+ WL+ A +P+ Q + GN L+I + D GT+ Sbjct: 906 IGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGN---LVISIAQKADMGTY 962 Query: 4792 TCRATTAAGQ 4801 C A A G+ Sbjct: 963 QCVAANAVGR 972 Score = 48.0 bits (109), Expect = 2e-04 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 9/110 (8%) Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532 ET FQ RL + + P S + +P L RA G+P P+I W KDG I+ Sbjct: 775 ETCFQ-RLEIFGDDWNTKPVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDG-RIV 832 Query: 533 P----NPELR--IHTDGGASTLD-IPRAKASDAAWYQCTAQNVAGSTATR 575 P + E R I +G + L I + + SD+ YQC A+N AG ++ Sbjct: 833 PTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSAGKAFSK 882 Score = 42.3 bits (95), Expect = 0.009 Identities = 46/180 (25%), Positives = 70/180 (38%), Gaps = 15/180 (8%) Query: 3074 PTGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132 P G + + W N K + RI+ V G +V+ I + D GTY C A N G+ Sbjct: 917 PKGRPAPTVTWLKNTKAYVPDGVRIQKVSP-GNLVISI--AQKADMGTYQCVAANAVGRR 973 Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191 + V + +S P I + + GQS F C D P + W G Sbjct: 974 KSRVATVTIKES----PTTALSIDPKQITVISGQSTSFSCQY--RDGPQAAVRWQKKGGD 1027 Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251 + + + T S L ++ Q D+GEYVC + G A + G ++ S Sbjct: 1028 LPLNRYVTTQSG----ELQLSSIQPGDAGEYVCSVPLESGVLSVSAKLEVQNYGRFFVSS 1083 Score = 41.9 bits (94), Expect = 0.012 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 8/87 (9%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI------NSNKHEIITTHN 319 P I P + + + +G+P+P++ W K+G R++ + N+ I+ + Sbjct: 792 PVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDG-RIVPTDGEDSENRRFIMPNGD 850 Query: 320 HTTLRVRN-TQKSDSGHYTLLAENPNG 345 T LRV N +KSDSG Y +AEN G Sbjct: 851 LTFLRVINKKRKSDSGVYQCVAENSAG 877 Score = 41.5 bits (93), Expect = 0.016 Identities = 68/293 (23%), Positives = 109/293 (37%), Gaps = 49/293 (16%) Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 G P P VTW KN + + I + L + QK+D G Y +A N G Sbjct: 919 GRPAPTVTWLKNTKAYVPDGVR--IQKVSPGNLVISIAQKADMGTYQCVAANAVG----- 971 Query: 351 GYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410 ++S+ T T + + I K + V G+ T Sbjct: 972 --------------RRKSRVATVTIKESPTTALSIDPKQIT-----------VISGQSTS 1006 Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470 F C+ P V W ++ D ++ + +SG L ++++ D+G C + Sbjct: 1007 FSCQYRDGPQAAVRW---QKKGGDLPLNRYVTTQSGE--LQLSSIQPGDAGEYVCSVPLE 1061 Query: 471 SGETAFQCRLNVIEKEQVVAPKFVE-RFSTLNVR-EGEPV--VLNARAVGTPTPR----- 521 SG + +L V + E R S++ EGE V L+ +G + R Sbjct: 1062 SGVLSVSAKLEVQNYGRFFVSSNGELRISSVKKEDEGEYVCSALSPAGLGASSARAMLTV 1121 Query: 522 -ITWQK--DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 + W K D + ++ N I T G + L I + DA Y+C N GS Sbjct: 1122 WLQWIKRDDSMRVLRNSSRVIITTGTLARLRISQLTLGDAGEYRCVVSNQLGS 1174 Score = 40.7 bits (91), Expect = 0.028 Identities = 54/210 (25%), Positives = 82/210 (39%), Gaps = 22/210 (10%) Query: 1736 PVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795 P G P V WL+N G + +++ D GTY C A N +G Sbjct: 917 PKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNLVISI--AQKADMGTYQCVAANAVGRRK 974 Query: 1796 TS-STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVN------QAP--RF 1846 + +T+ ++ + L S + I S Q R+ + AV P R+ Sbjct: 975 SRVATVTIKESPTTAL-SIDPKQITVISGQSTSFSCQYRDGPQAAVRWQKKGGDLPLNRY 1033 Query: 1847 ITQLNGPTKLSE---GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 +T +G +LS G + Y C + P + V +V G + +SN Sbjct: 1034 VTTQSGELQLSSIQPGDAGEYVCSV-PLESGVLSVSAKL--EVQNYGRFFVSSN----GE 1086 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933 L I +V ED GEY C A++ G SS R Sbjct: 1087 LRISSVKKEDEGEYVCSALSPAGLGASSAR 1116 Score = 39.9 bits (89), Expect = 0.049 Identities = 96/452 (21%), Positives = 164/452 (36%), Gaps = 47/452 (10%) Query: 97 GNPTPVVSWTR--KKAPLVECNKYSMRYNEQTGDVSLL--IKQIGPGDEGEYTCTARNQY 152 G+P P + W + + P + + R+ GD++ L I + D G Y C A N Sbjct: 817 GSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSA 876 Query: 153 GEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212 G+A G + +S T+ ++A + R V + Sbjct: 877 GKAFSKNATLEVGVLRSKFRAEP----KDLSITIGNRAI--LKCNPPKGRPAPTVTWLKN 930 Query: 213 TDHSSTDDFKVDTFEYRLL-------REVSFRESITKRYVGESDVQISTEIDRSLGPVSP 265 T D ++ L ++ + + VG +++T + P + Sbjct: 931 TKAYVPDGVRIQKVSPGNLVISIAQKADMGTYQCVAANAVGRRKSRVATVTIKE-SPTTA 989 Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 I P+ + G F Q P+ V W K G L N++ +TT + L++ Sbjct: 990 LSI--DPKQITVISGQSTSFSCQYRDGPQAAVRWQKKGGDL-PLNRY--VTTQS-GELQL 1043 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 + Q D+G Y +G + S L V++ +V I+ ++ E+ E Sbjct: 1044 SSIQPGDAGEYVCSVPLESGVLSVSAKLEVQNYGRFFVSSNGELRISSVKK---EDEGEY 1100 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 AL+P + R +T + + W D +R N ++ + Sbjct: 1101 VCSALSPAGLGASSAR----AMLTVW-----------LQWIKRDDSMRVLRNSSRVIITT 1145 Query: 446 GNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVR 503 G A L I+ +TL D+G CV N+ G L VI A + + S T+++ Sbjct: 1146 GTLARLRISQLTLGDAGEYRCVVSNQLGSVFAASFLTVIGIADFQALRIAKIVSLTIDLP 1205 Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNP 535 G P AR V T T K IP+P Sbjct: 1206 VGIPT--TAR-VTTRRSTSTKPKTSSIFIPDP 1234 Score = 39.5 bits (88), Expect = 0.065 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 8/94 (8%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG--VPIE---ASNRLTTMHDF 1765 PV T+ DI + NQ R G PK ++ WL++G VP + + NR M + Sbjct: 792 PVITLDPSDIVASRNQPTDLRCRA--TGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNG 849 Query: 1766 GYVALNM-KYVNPEDSGTYTCRAINELGEAVTSS 1798 L + DSG Y C A N G+A + + Sbjct: 850 DLTFLRVINKKRKSDSGVYQCVAENSAGKAFSKN 883 Score = 38.7 bits (86), Expect = 0.11 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 23/208 (11%) Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI----EASHRI 3097 DD P T DIV S Q TG I W +G+ + E S Sbjct: 786 DDWNTKPVITLDPSDIV-ASRNQPTDLRCRA--TGSPKPKIYWLKDGRIVPTDGEDSENR 842 Query: 3098 RTVYAFG-MVVLEILGTKT-TDSGTYSCRATNKWGQA-EISVKLEC-VDKSKGQKPRFTT 3153 R + G + L ++ K +DSG Y C A N G+A + LE V +SK F Sbjct: 843 RFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSAGKAFSKNATLEVGVLRSK-----FRA 897 Query: 3154 HIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP-MRHSTRIKTVSDFGFVVLDIA 3212 +++ + G A +C P P + W N + + RI+ VS G +V+ IA Sbjct: 898 EPKDL-SITIGNRAILKCN-PPKGRPAPTVTWLKNTKAYVPDGVRIQKVSP-GNLVISIA 954 Query: 3213 YTQNHDSGEYVCRAYNKYGEDFTR-ATI 3239 Q D G Y C A N G +R AT+ Sbjct: 955 --QKADMGTYQCVAANAVGRRKSRVATV 980 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 6/75 (8%) Query: 79 KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138 K G + F + R P V W +K L N+Y Q+G++ L I P Sbjct: 995 KQITVISGQSTSFSCQYRDGPQAAVRWQKKGGDL-PLNRY---VTTQSGELQL--SSIQP 1048 Query: 139 GDEGEYTCTARNQYG 153 GD GEY C+ + G Sbjct: 1049 GDAGEYVCSVPLESG 1063 Score = 35.1 bits (77), Expect = 1.4 Identities = 56/232 (24%), Positives = 93/232 (40%), Gaps = 16/232 (6%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 + +F+ KD +SI G A + P G V WLK+ + + G + Sbjct: 892 RSKFRAEPKD-LSITIGNRAILKCN-PPKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNL 949 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI--QYLED 1025 ++I D G Y C A NA+G+ + + + A S P + I Q Sbjct: 950 VISIAQKA--DMGTYQCVAANAVGRRKSRVATVTIKESPTTALSIDPKQITVISGQSTSF 1007 Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFE-ARVEP--QSDLTMTVEWYFN 1082 + +Y + V+ +K L PL N+ V QS + + ++P + +V Sbjct: 1008 SCQYRDGPQAAVRWQKKGGDL-PL---NRYVTTQSGELQLSSIQPGDAGEYVCSVPLESG 1063 Query: 1083 GKQITSANRIQTYHDFGYVA---LDIASVRAEDSGVYTVVARNAAGEAQLSA 1131 +++ +Q Y F + L I+SV+ ED G Y A + AG SA Sbjct: 1064 VLSVSAKLEVQNYGRFFVSSNGELRISSVKKEDEGEYVCSALSPAGLGASSA 1115 Score = 34.7 bits (76), Expect = 1.9 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 12/130 (9%) Query: 1838 VAVNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPD-PNMRVEWYFNGKVLQSGHRYR 1894 V + ++P ++ P +++ GQS + C+ Y D P V W G L +RY Sbjct: 980 VTIKESPTTALSID-PKQITVISGQSTSFSCQ---YRDGPQAAVRWQKKGGDLPL-NRYV 1034 Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954 T+ L + ++ D+GEY C G S +L VQ+ S E + Sbjct: 1035 TTQS---GELQLSSIQPGDAGEYVCSVPLESGVLSVSAKLEVQNYGRFFVSSNGELRISS 1091 Query: 1955 IQYLEDDSRY 1964 ++ ED+ Y Sbjct: 1092 VK-KEDEGEY 1100 Score = 34.3 bits (75), Expect = 2.5 Identities = 13/41 (31%), Positives = 19/41 (46%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 PV P + + CR TG PKP++ WL +G + Sbjct: 792 PVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDGRIV 832 Score = 34.3 bits (75), Expect = 2.5 Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 8/108 (7%) Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRP-VQQGHRFKTTYDFG 2033 V + +F K+ +T G+ L+ P P V W N + V G R + G Sbjct: 890 VLRSKFRAEPKDLSITIGNRAILKCN-PPKGRPAPTVTWLKNTKAYVPDGVRIQKVSP-G 947 Query: 2034 YVALDILYAYAEDTGTYMCKATNAVG---EAVTTSSVKVDAKSGLYLD 2078 + + I A D GTY C A NAVG V T ++K + L +D Sbjct: 948 NLVISI--AQKADMGTYQCVAANAVGRRKSRVATVTIKESPTTALSID 993 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%) Query: 657 ETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI------QDSGEYT 710 + R G P KI WLK+G+ + + RF + D+ L + DSG Y Sbjct: 810 DLRCRATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQ 869 Query: 711 CRAVSATGVAETK-AVLHV 728 C A ++ G A +K A L V Sbjct: 870 CVAENSAGKAFSKNATLEV 888 Score = 33.5 bits (73), Expect = 4.3 Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 17/120 (14%) Query: 2356 LESAEPFK--RPEIPEPVTRQRPVF-----TQPLQNID--NIQEGQTAHFDCRLIPVGDP 2406 + AE FK R + E ++ +F T+P+ +D +I + D R G P Sbjct: 760 ISQAERFKLRRESVCETCFQRLEIFGDDWNTKPVITLDPSDIVASRNQPTDLRCRATGSP 819 Query: 2407 TLKVEWFRNEKLI----EDSSR---ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 K+ W ++ +++ EDS I D ++ + I+ R D GVY C A N G+ Sbjct: 820 KPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRV-INKKRKSDSGVYQCVAENSAGK 878 Score = 33.5 bits (73), Expect = 4.3 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 5/73 (6%) Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKL-IEDSSRITKTHDFGYVSMTISHVRDED 2445 +I G A C P G P V W +N K + D RI K V IS + D Sbjct: 903 SITIGNRAILKCNP-PKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNLV---ISIAQKAD 958 Query: 2446 EGVYMCRASNLLG 2458 G Y C A+N +G Sbjct: 959 MGTYQCVAANAVG 971 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 6/63 (9%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDF----GLVTLS--INSLRNDDSGIYTCKATNLLGE 2725 P KI W K+G + T F G +T IN R DSG+Y C A N G+ Sbjct: 819 PKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSAGK 878 Query: 2726 AVS 2728 A S Sbjct: 879 AFS 881 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 6/74 (8%) Query: 940 TLRVEWLKDG---RPVEASSRITTFFNFGYVA-LTIKSVTVHDAGHYTCRAYNAIGQATT 995 T+ ++W+K R + SSR+ G +A L I +T+ DAG Y C N +G Sbjct: 1120 TVWLQWIKRDDSMRVLRNSSRV--IITTGTLARLRISQLTLGDAGEYRCVVSNQLGSVFA 1177 Query: 996 SANLTIVTKKDIIA 1009 ++ LT++ D A Sbjct: 1178 ASFLTVIGIADFQA 1191 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 10/91 (10%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-------VKTIN 3610 P T PSD++ S N CR ++ W +G+ + T + Sbjct: 792 PVITLDPSDIVASRNQPTDLRCR--ATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNG 849 Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEA 3641 D F+ + I + D+G+Y C A N G+A Sbjct: 850 DLTFLRV-INKKRKSDSGVYQCVAENSAGKA 879 >SB_8553| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 982 Score = 85.0 bits (201), Expect = 1e-15 Identities = 80/311 (25%), Positives = 127/311 (40%), Gaps = 40/311 (12%) Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585 TS + + LD K T D W K+GKK+ +++ + Y L I +DSG+Y Sbjct: 68 TSREALVLDQKDVFT---DYIWYKDGKKMSVSHSSRMRIKRLRY-LKIKNLDKEDSGRYT 123 Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645 CVA GE + V P T K + + I P+ G +++ C Sbjct: 124 CVAKRPCGEISANITLTVDSPPTFTVSKLKREKTL----IAMPV-------GNSLKLDCS 172 Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705 GKP PTV W K K ++S +Y L + +A P D+G Y C N+ G + Sbjct: 173 ADGKPRPTVVWLKNGKPFLKRDGVELSLRPYQYVLSMRDAVPSDDGRYTCNVSNALGWIN 232 Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR------EGA 4759 + V + +A P L P+ ++ V G+ A + + S P QW+R G+ Sbjct: 233 HTYTVDVRERVRAK--PVLQPIANVTVLSGENATLECKAMSDSMPHFQWIRWFTARVNGS 290 Query: 4760 LIPETPDFQMIHEG-----------------NNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802 T F+++ + + L + N +ED G +TC A G Sbjct: 291 SNETTLRFEVVKQTPHSDHILRPKSEHRFAFHGVKLTLFNVSKEDEGKYTCLVGNAVGYN 350 Query: 4803 ETSAKLVVKSK 4813 + L+VK + Sbjct: 351 AENGYLIVKDQ 361 Score = 55.2 bits (127), Expect = 1e-06 Identities = 34/151 (22%), Positives = 60/151 (39%), Gaps = 2/151 (1%) Query: 420 YPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCR 479 + + W+ + +++ ++ ++ + L I N+ DSG TCVA+ GE + Sbjct: 81 FTDYIWYKDGKKMSVSHSSRMRIKRL--RYLKIKNLDKEDSGRYTCVAKRPCGEISANIT 138 Query: 480 LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539 L V K + + + G + L+ A G P P + W K+G P + + + Sbjct: 139 LTVDSPPTFTVSKLKREKTLIAMPVGNSLKLDCSADGKPRPTVVWLKNGKPFLKRDGVEL 198 Query: 540 HTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 L + A SD Y C N G Sbjct: 199 SLRPYQYVLSMRDAVPSDDGRYTCNVSNALG 229 Score = 51.6 bits (118), Expect = 2e-05 Identities = 82/332 (24%), Positives = 127/332 (38%), Gaps = 57/332 (17%) Query: 1064 EARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122 EA V Q D+ WY +GK+++ S + Y L I ++ EDSG YT VA+ Sbjct: 71 EALVLDQKDVFTDYIWYKDGKKMSVSHSSRMRIKRLRY--LKIKNLDKEDSGRYTCVAKR 128 Query: 1123 AAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQP 1182 GE + ++TV++ P + + ++ + K + P Sbjct: 129 PCGEISANITLTVDS--------------------------PPTFTVSKLKREKTLIAMP 162 Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242 + N ++ L+C + G P V W NG+ + L + A Sbjct: 163 VGN--------SLKLDCSAD--GKPRPTVVWLKNGKPFLKRDGVELSLRPYQYVLSMRDA 212 Query: 1243 TSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL--EDAARRTKQ 1300 +D G YT N LG + + V V ER V Q I + +L E+A K Sbjct: 213 VPSDDGRYTCNVSNALGWINHTYTVDVRER---VRAKPVLQPIANVTVLSGENATLECKA 269 Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360 + + + Q ++ A N + E T + P D +R K+ HRF Sbjct: 270 MSDSMPHFQWIRWFTARVNGSSNETTLRFEVVKQTPHSDHILRP---------KSEHRFA 320 Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392 F V L L +V ED G YTC N +G Sbjct: 321 ----FHGVKLTLFNVSKEDEGKYTCLVGNAVG 348 Score = 46.4 bits (105), Expect = 6e-04 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 1/108 (0%) Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299 + KR GE I+ +D S + K+ ++ + G + G PRP V W Sbjct: 125 VAKRPCGEISANITLTVD-SPPTFTVSKLKREKTLIAMPVGNSLKLDCSADGKPRPTVVW 183 Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347 KNG+ + + E+ L +R+ SD G YT N G I Sbjct: 184 LKNGKPFLKRDGVELSLRPYQYVLSMRDAVPSDDGRYTCNVSNALGWI 231 Score = 44.0 bits (99), Expect = 0.003 Identities = 58/221 (26%), Positives = 89/221 (40%), Gaps = 30/221 (13%) Query: 1738 GDPKLRVEWLRNGVP-IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796 G P+ V WL+NG P ++ ++ + YV L+M+ P D G YTC N LG Sbjct: 175 GKPRPTVVWLKNGKPFLKRDGVELSLRPYQYV-LSMRDAVPSDDGRYTCNVSNALGWINH 233 Query: 1797 SSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856 + T+ V+ + + + LQ I + S + + + P F + T Sbjct: 234 TYTVDVRERV------RAKPVLQPIANVTVLSGENATLECKAMSDSMPHF-QWIRWFTAR 286 Query: 1857 SEGQSAHYECRIE-----PYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911 G S R E P+ D +R +S HR+ F L + V Sbjct: 287 VNGSSNETTLRFEVVKQTPHSDHILRP---------KSEHRFA----FHGVKLTLFNVSK 333 Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ---SKESIIRDSQHE 1949 ED G+YTC N +G + L V+ S S + D+Q E Sbjct: 334 EDEGKYTCLVGNAVGYNAENGYLIVKDQFSTTSTVIDTQAE 374 Score = 43.6 bits (98), Expect = 0.004 Identities = 28/119 (23%), Positives = 47/119 (39%), Gaps = 3/119 (2%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 G + DC G+P P V W N + ++ + + L + + SD G TC Sbjct: 164 GNSLKLDCSADGKPRPTVVWLKNGKPFLKRDGVELSLRPY-QYVLSMRDAVPSDDGRYTC 222 Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524 N G ++V +E+V A ++ + + V GE L +A+ P W Sbjct: 223 NVSNALGWINHTYTVDV--RERVRAKPVLQPIANVTVLSGENATLECKAMSDSMPHFQW 279 Score = 43.2 bits (97), Expect = 0.005 Identities = 59/227 (25%), Positives = 89/227 (39%), Gaps = 29/227 (12%) Query: 3693 NPPRFTVEI----KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH-TL 3747 +PP FTV K I +P G + DC + G P + W NG+PF V +L Sbjct: 143 SPPTFTVSKLKREKTLIAMPVGNSLKLDCSAD--GKPRPTVVWLKNGKPFLKRDGVELSL 200 Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNK--WGSATTTAKITCSAKRDIVLESQLPQGMSG 3805 + ++ L + D G YTC +N W + T T + + VL+ + Sbjct: 201 RPYQYV-LSMRDAVPSDDGRYTCNVSNALGWINHTYTVDVRERVRAKPVLQPIANVTVLS 259 Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE-CRVEPKEDPKLRIE 3864 + LE +SD+ P F ++ + E + +RFE + P D LR + Sbjct: 260 GENATLECKAMSDS---MPHFQWIRWFTARVNGSSNETT--LRFEVVKQTPHSDHILRPK 314 Query: 3865 WYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 S HR+ V L + V ED G+Y C N G Sbjct: 315 ---------SEHRFA----FHGVKLTLFNVSKEDEGKYTCLVGNAVG 348 Score = 39.9 bits (89), Expect = 0.049 Identities = 34/148 (22%), Positives = 54/148 (36%), Gaps = 4/148 (2%) Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143 W+ +GK + SH R + + L+I DSG Y+C A G+ ++ L VD Sbjct: 86 WYKDGKKMSVSHSSR-MRIKRLRYLKIKNLDKEDSGRYTCVAKRPCGEISANITL-TVDS 143 Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203 + + + G S +C+ P + W NG+P ++ Sbjct: 144 PPTFTVSKLKREKTLIAMPVGNSLKLDCSA--DGKPRPTVVWLKNGKPFLKRDGVELSLR 201 Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 VL + D G Y C N G Sbjct: 202 PYQYVLSMRDAVPSDDGRYTCNVSNALG 229 Score = 39.9 bits (89), Expect = 0.049 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 W+K+G+++ S+ + L+++N K DSG YT +A+ P G I + L V+SP Sbjct: 86 WYKDGKKMSVSHSSRM-RIKRLRYLKIKNLDKEDSGRYTCVAKRPCGEISANITLTVDSP 144 Score = 39.5 bits (88), Expect = 0.065 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 8/89 (8%) Query: 3972 PPRF-VTQIQSQTSLVEM---ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF-TPIY 4026 PP F V++++ + +L+ M + K +C G P V W NGKP L ++ + Sbjct: 144 PPTFTVSKLKREKTLIAMPVGNSLKLDCSAD--GKPRPTVVWLKNGKPFLKRDGVELSLR 201 Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055 + YV ++ P D G Y C +N G Sbjct: 202 PYQYV-LSMRDAVPSDDGRYTCNVSNALG 229 Score = 34.7 bits (76), Expect = 1.9 Identities = 17/68 (25%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 86 GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145 G + K + G P P V W + P ++ + + + + L ++ P D+G YT Sbjct: 164 GNSLKLDCSADGKPRPTVVWLKNGKPFLK--RDGVELSLRPYQYVLSMRDAVPSDDGRYT 221 Query: 146 CTARNQYG 153 C N G Sbjct: 222 CNVSNALG 229 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 3/65 (4%) Query: 806 WYKDGRPITAS-SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864 WYKDG+ ++ S S I Y L I +L ED+G YT A GE + ++ V + Sbjct: 86 WYKDGKKMSVSHSSRMRIKRLRY--LKIKNLDKEDSGRYTCVAKRPCGEISANITLTVDS 143 Query: 865 RSTVT 869 T T Sbjct: 144 PPTFT 148 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938 WY +GK + H R L I + EDSG YTC A G+ ++I L V S Sbjct: 86 WYKDGKKMSVSHSSRMRIK-RLRYLKIKNLDKEDSGRYTCVAKRPCGEISANITLTVDS 143 Score = 33.9 bits (74), Expect = 3.2 Identities = 61/241 (25%), Positives = 88/241 (36%), Gaps = 22/241 (9%) Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK--VEWFKNGQPVTIGHRFR-P 1495 +V P F E + V KL+ D + V W KNG+P Sbjct: 140 TVDSPPTFTVSKLKREKTLIAMPVGNSLKLDCSADGKPRPTVVWLKNGKPFLKRDGVELS 199 Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555 + + YV L + D + D G YTC N +G + + R + VR+ + + Sbjct: 200 LRPYQYV-LSMRDAVPSDDGRYTCNVSNALGWINHTYTVDVR---ERVRAKPVLQPIANV 255 Query: 1556 QVLE-DRSKYHRTDMVDEVT-TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEW 1613 VL + + M D + Q T+ N E + P SD Sbjct: 256 TVLSGENATLECKAMSDSMPHFQWIRWFTARVNGSSNETTLRFEVVKQTPHSD------- 308 Query: 1614 YHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673 H +P KS RF F V L + + ED G YTC NA+G +G IV + Sbjct: 309 -HILRP-KSEHRFA----FHGVKLTLFNVSKEDEGKYTCLVGNAVGYNAENGYLIVKDQF 362 Query: 1674 S 1674 S Sbjct: 363 S 363 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 5/57 (8%) Query: 1480 WFKNGQPVTIGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 W+K+G+ +++ H R I Y+ + +D EDSG YTC A G E+S +T Sbjct: 86 WYKDGKKMSVSHSSRMRIKRLRYLKIKNLD--KEDSGRYTCVAKRPCG--EISANIT 138 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 2/102 (1%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTD--PNLKIEWFKNGVTLTTGARLKSTF 2695 V P FT +K + V +++ D P + W KNG ++ + Sbjct: 141 VDSPPTFTVSKLKREKTLIAMPVGNSLKLDCSADGKPRPTVVWLKNGKPFLKRDGVELSL 200 Query: 2696 DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 LS+ D G YTC +N LG T ++ + +R Sbjct: 201 RPYQYVLSMRDAVPSDDGRYTCNVSNALGWINHTYTVDVRER 242 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 4/69 (5%) Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLDITHTYEEDSGIY 2846 G+++ +C+ + PT + W N KP + S + YV L + D G Y Sbjct: 164 GNSLKLDCSADGKPRPT--VVWLKNGKPFLKRDGVELSLRPYQYV-LSMRDAVPSDDGRY 220 Query: 2847 TCKATNSKG 2855 TC +N+ G Sbjct: 221 TCNVSNALG 229 Score = 33.1 bits (72), Expect = 5.7 Identities = 15/49 (30%), Positives = 22/49 (44%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991 V WLK+G+P + L+++ D G YTC NA+G Sbjct: 181 VVWLKNGKPFLKRDGVELSLRPYQYVLSMRDAVPSDDGRYTCNVSNALG 229 Score = 32.7 bits (71), Expect = 7.5 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 3/58 (5%) Query: 945 WLKDGRPVEAS-SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 W KDG+ + S S Y L IK++ D+G YTC A G+ + + LT+ Sbjct: 86 WYKDGKKMSVSHSSRMRIKRLRY--LKIKNLDKEDSGRYTCVAKRPCGEISANITLTV 141 >SB_5639| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1384 Score = 83.8 bits (198), Expect = 3e-15 Identities = 79/310 (25%), Positives = 123/310 (39%), Gaps = 37/310 (11%) Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335 ++ E + + + G P+P VTW +N Q + SN + N L + N SD+G Sbjct: 974 RVVEKMNVRIHCPIVGFPKPVVTWTRNNQD-VRSNAR-LFVDPNTNDLLINNILTSDTGQ 1031 Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395 Y A NP G S ++++ S + + + +T + ++ P V Sbjct: 1032 YICSAVNPIGEDEKSSFISIISEASAEIIRGNASLVTSSNRK--------------PVTV 1077 Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH-KILVNE--SGNHALMI 452 + +V G C V G P P + W + +I + L+ + SG L+I Sbjct: 1078 VIGNSLEVLSGTDVTIVCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILII 1137 Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--------------S 498 VT SG CVA N G + VIE +Q V +R + Sbjct: 1138 AQVTKDVSGSYECVASNVGGADRVATSIQVIEAQQPVIEFISKRLQSLKDLSAVTATIGT 1197 Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558 T+ + G +VL + G P P +W +G P+ E D + L IP D+ Sbjct: 1198 TITLLAGAKLVLQCPSTGVPLPSTSWSLNGEPL----EKGGRADLRGTELVIPAVAGVDS 1253 Query: 559 AWYQCTAQNV 568 YQCTA NV Sbjct: 1254 GKYQCTASNV 1263 Score = 66.1 bits (154), Expect = 7e-10 Identities = 54/195 (27%), Positives = 86/195 (44%), Gaps = 21/195 (10%) Query: 395 VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454 + + QD V E R C + G P P VTW N++ +R N ++ V+ + N L+I N Sbjct: 967 ITIGQDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQDVRS--NARLFVDPNTND-LLINN 1023 Query: 455 VTLSDSGVVTCVARNKSGETAFQCRLNVIEK--EQVV------------APKFVERFSTL 500 + SD+G C A N GE +++I + +++ P V ++L Sbjct: 1024 ILTSDTGQYICSAVNPIGEDEKSSFISIISEASAEIIRGNASLVTSSNRKPVTVVIGNSL 1083 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP---ELRIHTD-GGASTLDIPRAKAS 556 V G V + GTP+P I W+ DG+ I + + D G L I + Sbjct: 1084 EVLSGTDVTIVCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKD 1143 Query: 557 DAAWYQCTAQNVAGS 571 + Y+C A NV G+ Sbjct: 1144 VSGSYECVASNVGGA 1158 Score = 63.7 bits (148), Expect = 3e-09 Identities = 72/290 (24%), Positives = 115/290 (39%), Gaps = 24/290 (8%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G+P P + WY + PI I + I I +++ + + A NR K S Sbjct: 494 GKPTPTVYWYSQGRPIAVGKAVTIG--NNLRIENIDKIYALE---YTCHAYNRRARTKES 548 Query: 4496 ANL--------VVEEKRRQGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVY 4546 + + ++ +R+ PS +T N+ V +G V + V + Sbjct: 549 SVVNVLDLAPPIIAAERKVISVDKTTPSMDITIGTNLTVMAGTDVVVRCPVKTRPEPGLS 608 Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606 W G P L+ D + TLL+ D+G Y C+A N+AG+ + V+ P Sbjct: 609 WRIRGLAFDPKTSRAKLQNDNS-TLLLSGLTKDDAGSYTCIARNNAGKDQKVTNIQVADP 667 Query: 4607 ATKDKPKPQTKAANAPPEIIEPLK----DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662 K Q+ ++ IE V G + C G P P V W + Sbjct: 668 Q-KPTIISQSGFKSSHESDIEMTVTIGIQTTVLSGITLTIICPTRGLPAPDVTWEMNNTN 726 Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 ++P F E TL I +D+G+ +CVA N+AG+ T +KL V Sbjct: 727 VRPGGRF----VVQEGTLTIRNLVKQDQGNIRCVARNAAGQDTATSKLNV 772 Score = 60.9 bits (141), Expect = 2e-08 Identities = 74/298 (24%), Positives = 119/298 (39%), Gaps = 43/298 (14%) Query: 4436 GEPLPLIKWYRENFPIKNSP---DFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491 G P P I W + I + F + S + ILII QV + S + VA N GG Sbjct: 1099 GTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGSYECVASNVGGA 1158 Query: 4492 AKCSANLVVEE----------KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541 + + ++ V E KR Q + + T+ + + +G + L TG Sbjct: 1159 DRVATSIQVIEAQQPVIEFISKRLQSLKDLSAVTATI-GTTITLLAGAKLVLQCPSTGVP 1217 Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601 W NG+ ++ R + GT L+I DSGKY+C A N ++ Sbjct: 1218 LPSTSWSLNGEPLEKGGRADLR---GT-ELVIPAVAGVDSGKYQCTASNVIALDSRASDV 1273 Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-------VAEGQAIEFSCKIVGKPLPTV 4654 V +D KP+ + A ++ E +K + G ++E C G P PT+ Sbjct: 1274 TV-----RDPTKPKIRGAPKDMDLFEIMKLSVDVGSTITTIPGVSLELKCSAQGLPAPTI 1328 Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 +W G+ ++ D TL++ + D Y CVA N AG + + L + Sbjct: 1329 RWRLGEIVV------------DSDTLKLPQLKVGDSRTYTCVASNVAGNDSKSTVLNI 1374 Score = 58.8 bits (136), Expect = 1e-07 Identities = 53/211 (25%), Positives = 82/211 (38%), Gaps = 20/211 (9%) Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N + G D + + P P ++W G + N +TL + K D+ Sbjct: 584 NLTVMAGTDVVVRCPVKTRPEPGLSWRIRGLAFDPKTSRAKLQNDN-STLLLSGLTKDDA 642 Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393 G YT +A N G + V P + + Q + E IE++ Sbjct: 643 GSYTCIARNNAGKDQKVTNIQVADPQKPTIISQSGF------KSSHESDIEMT------- 689 Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453 V + V G C G P P+VTW +N+ +R + +V E L I Sbjct: 690 -VTIGIQTTVLSGITLTIICPTRGLPAPDVTWEMNNTNVRP--GGRFVVQEG---TLTIR 743 Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484 N+ D G + CVARN +G+ +LNVI+ Sbjct: 744 NLVKQDQGNIRCVARNAAGQDTATSKLNVID 774 Score = 58.8 bits (136), Expect = 1e-07 Identities = 93/423 (21%), Positives = 156/423 (36%), Gaps = 47/423 (11%) Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477 Q RV E R G P P++ W R N ++++ ++ + L+I + D Sbjct: 971 QDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQDVRSNA--RLFVDPNTNDLLINNILTSD 1028 Query: 4478 SAVFAAVAENR-GGTAKCSANLVVEEKRRQ---GRGGIV-----PPSFTLTAQNVNVTSG 4528 + + A N G K S ++ E + G +V P + ++ V SG Sbjct: 1029 TGQYICSAVNPIGEDEKSSFISIISEASAEIIRGNASLVTSSNRKPVTVVIGNSLEVLSG 1088 Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKV-QPDIRNKIL---EEDGTYTLLILEAYPQDSGKY 4584 V + V GT ++W +G ++ + + L + G L+I + SG Y Sbjct: 1089 TDVTIVCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGSY 1148 Query: 4585 ECVAINSAGEAR--CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIE 4641 ECVA N G R + + + + + ++ + + I + G + Sbjct: 1149 ECVASNVGGADRVATSIQVIEAQQPVIEFISKRLQSLKDLSAVTATIGTTITLLAGAKLV 1208 Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN-- 4699 C G PLP+ W + ++ + T L I D G Y+C A N Sbjct: 1209 LQCPSTGVPLPSTSWSLNGEPLEKGGRADLRGT----ELVIPAVAGVDSGKYQCTASNVI 1264 Query: 4700 ----SAGRVTV--AAKLKVT-QPDQADNLPALTPLRD----IVVYEGQPAQFKTQITSKI 4748 A VTV K K+ P D + D I G + K Sbjct: 1265 ALDSRASDVTVRDPTKPKIRGAPKDMDLFEIMKLSVDVGSTITTIPGVSLELKCSAQGLP 1324 Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 PTI+W R G ++ ++ ++ L +G D+ T+TC A+ AG S L Sbjct: 1325 APTIRW-RLGEIVVDSDTLKL------PQLKVG-----DSRTYTCVASNVAGNDSKSTVL 1372 Query: 4809 VVK 4811 +K Sbjct: 1373 NIK 1375 Score = 56.8 bits (131), Expect = 4e-07 Identities = 58/241 (24%), Positives = 98/241 (40%), Gaps = 26/241 (10%) Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPA-TKDKPKPQTKAANAPPEI---IEPLKDKIVA 4635 + G Y+C A AG + A + L T + KA+ P + I + Sbjct: 422 NEGTYQCKATRLAGASSTAAFTLKILALNTPTILSAKGKASFGPRDADVTITVGTTVTLY 481 Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695 +G + C ++GKP PTV WY + I K + LRI +Y C Sbjct: 482 KGTTLTIKCPVMGKPTPTVYWYSQGRPIAVGKAVTIGN-----NLRIENIDKIYALEYTC 536 Query: 4696 VAYNSAGRV--------------TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741 AYN R +AA+ KV D+ +T ++ V G + Sbjct: 537 HAYNRRARTKESSVVNVLDLAPPIIAAERKVISVDKTTPSMDITIGTNLTVMAGTDVVVR 596 Query: 4742 TQITSKIKPTIQW-LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 + ++ +P + W +R A P+T ++ + +N+ LL+ ++D G++TC A AG Sbjct: 597 CPVKTRPEPGLSWRIRGLAFDPKTSRAKL--QNDNSTLLLSGLTKDDAGSYTCIARNNAG 654 Query: 4801 Q 4801 + Sbjct: 655 K 655 Score = 56.0 bits (129), Expect = 7e-07 Identities = 92/376 (24%), Positives = 159/376 (42%), Gaps = 58/376 (15%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248 V E N+ + C + +G P V W N + V +R + D L I + ++DTG Sbjct: 975 VVEKMNVRIHCPI--VGFPKPVVTWTRNNQDVRSNARL--FVDPNTNDLLINNILTSDTG 1030 Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVM 1308 +Y AVN +G S+ + +I +E + E I+ +A+ T R+ +TV+ Sbjct: 1031 QYICSAVNPIGEDEKSSFISII----------SEASAEIIR--GNASLVTSSNRKPVTVV 1078 Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH-RFRPAYEFDY 1367 +++E + GT+V + C ++ G + + W +G I +G + + D Sbjct: 1079 IG-------NSLEVLSGTDVTIVCPVR--GTPSPFIFWRHDGLRIASGQGKGQFLLGKDN 1129 Query: 1368 VALDLL---SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYL 1424 D+L V + SG Y C A+N G + +++VI + ++E +++Q L Sbjct: 1130 SGRDILIIAQVTKDVSGSYECVASNVGGADRVATSIQVIEAQQPVIEFIS----KRLQSL 1185 Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL-KVEWFKN 1483 +D S T I ++T+ + G + +C P T L W N Sbjct: 1186 KDLSAVTAT--IGTTITL--------------LAGAKLVLQC---PSTGVPLPSTSWSLN 1226 Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDI 1542 G+P+ G R D L I + DSG Y C A N++ D + +T R T Sbjct: 1227 GEPLEKGGR----ADLRGTELVIPAVAGVDSGKYQCTASNVIALDSRASDVTVRDPTKPK 1282 Query: 1543 VRSTQNEAGLEQIQVL 1558 +R + L +I L Sbjct: 1283 IRGAPKDMDLFEIMKL 1298 Score = 55.6 bits (128), Expect = 9e-07 Identities = 67/316 (21%), Positives = 119/316 (37%), Gaps = 39/316 (12%) Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336 L +G + + G P P V W+ G+ + + +T N+ LR+ N K + Y Sbjct: 480 LYKGTTLTIKCPVMGKPTPTVYWYSQGRPIAVG---KAVTIGNN--LRIENIDKIYALEY 534 Query: 337 TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396 T A N S + V + +R D +T ++I+ Sbjct: 535 TCHAYNRRARTKESSVVNVLDLAPPIIAAERKVISVD----KTTPSMDIT---------- 580 Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456 + + V G C V RP P ++W I + L N+ N L+++ +T Sbjct: 581 IGTNLTVMAGTDVVVRCPVKTRPEPGLSWRIRGLAFDPKTSRAKLQND--NSTLLLSGLT 638 Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVI--EKEQVVA--------PKFVERFSTLNVR--- 503 D+G TC+ARN +G+ + V +K +++ +E T+ ++ Sbjct: 639 KDDAGSYTCIARNNAGKDQKVTNIQVADPQKPTIISQSGFKSSHESDIEMTVTIGIQTTV 698 Query: 504 -EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562 G + + G P P +TW+ + + P + TL I D + Sbjct: 699 LSGITLTIICPTRGLPAPDVTWEMNNTNVRPGGRFVVQ----EGTLTIRNLVKQDQGNIR 754 Query: 563 CTAQNVAGSTATRARL 578 C A+N AG ++L Sbjct: 755 CVARNAAGQDTATSKL 770 Score = 50.8 bits (116), Expect = 3e-05 Identities = 88/358 (24%), Positives = 143/358 (39%), Gaps = 59/358 (16%) Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777 +D+RV E + VG PK V W RN + ++ RL + + +N + Sbjct: 971 QDLRVVEKMNVRIHCPI--VGFPKPVVTWTRNNQDVRSNARLFVDPNTNDLLINN--ILT 1026 Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837 D+G Y C A+N +GE SS + + S+AS ++ + S L SS R+ V Sbjct: 1027 SDTGQYICSAVNPIGEDEKSSFISIISEASAEIIRGNAS-------LVTSS---NRKPVT 1076 Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH---RYR 1894 V + + ++ G C + P P + W +G + SG ++ Sbjct: 1077 VVIGNS----------LEVLSGTDVTIVCPVRGTPSP--FIFWRHDGLRIASGQGKGQFL 1124 Query: 1895 TSND-FGFAALDILTVYGEDSGEYTCKAINNLG--QAVSSIRLNVQSKESIIRDSQHESA 1951 D G L I V + SG Y C A N G + +SI++ +++++ +I E Sbjct: 1125 LGKDNSGRDILIIAQVTKDVSGSYECVASNVGGADRVATSIQV-IEAQQPVI-----EFI 1178 Query: 1952 LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011 +++Q L+D S + G I + G + L+ T V P Sbjct: 1179 SKRLQSLKDLSAVTATI------------GTTI---TLLAGAKLVLQCPSTGV--PLPST 1221 Query: 2012 EWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 W NG P+++G R D L I D+G Y C A+N + S V V Sbjct: 1222 SWSLNGEPLEKGGR----ADLRGTELVIPAVAGVDSGKYQCTASNVIALDSRASDVTV 1275 Score = 48.4 bits (110), Expect = 1e-04 Identities = 69/263 (26%), Positives = 107/263 (40%), Gaps = 39/263 (14%) Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG 3751 P T+ + + + +G + C V +G PT + W+ GRP A G V N+ Sbjct: 465 PRDADVTITVGTTVTLYKGTTLTIKCPV--MGKPTPTVYWYSQGRPIAVGKAVTIGNNLR 522 Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811 +ID IYA EYTC A N+ ++ + VL+ P + K+ + Sbjct: 523 I--ENIDKIYAL---EYTCHAYNRRARTKESSVVN-------VLDLAPPIIAAERKVISV 570 Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871 ++ +TP IT + TV V C V+ + +P L W G Sbjct: 571 DK-------------TTPSMDITIGTNLTVMAGTDVVVRCPVKTRPEPGL--SWRIRGLA 615 Query: 3872 L-PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED--FTKATISCKKLPDII 3928 P R + D + L L +D+G Y C A N+ G+D T ++ + P II Sbjct: 616 FDPKTSRAKLQNDNSTLLLSGL--TKDDAGSYTCIARNNAGKDQKVTNIQVADPQKPTII 673 Query: 3929 LQNQVPRGMKRS-EALTQMEATI 3950 Q+ G K S E+ +M TI Sbjct: 674 SQS----GFKSSHESDIEMTVTI 692 Score = 46.8 bits (106), Expect = 4e-04 Identities = 71/309 (22%), Positives = 115/309 (37%), Gaps = 48/309 (15%) Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSN-KHEIITTHNHT---TLRVRNTQKSDSGH 335 G D + G P P + W +G R+ + K + + +++ L + K SG Sbjct: 1088 GTDVTIVCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGS 1147 Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395 Y +A N G + + V + ++ +I+ Q S K L+ Sbjct: 1148 YECVASNVGGADRVATSIQVIEAQQPVIE-----FISKRLQ---------SLKDLSAVTA 1193 Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455 + + G C TG P P +W +N + + E L+I V Sbjct: 1194 TIGTTITLLAGAKLVLQCPSTGVPLPSTSWSLNGEPLEKGGRADLRGTE-----LVIPAV 1248 Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIE--KEQVV-APKFVERF----------STLNV 502 DSG C A N + + V + K ++ APK ++ F ST+ Sbjct: 1249 AGVDSGKYQCTASNVIALDSRASDVTVRDPTKPKIRGAPKDMDLFEIMKLSVDVGSTITT 1308 Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562 G + L A G P P I W+ E+ + +D TL +P+ K D+ Y Sbjct: 1309 IPGVSLELKCSAQGLPAPTIRWRLG--------EIVVDSD----TLKLPQLKVGDSRTYT 1356 Query: 563 CTAQNVAGS 571 C A NVAG+ Sbjct: 1357 CVASNVAGN 1365 Score = 44.4 bits (100), Expect = 0.002 Identities = 45/187 (24%), Positives = 70/187 (37%), Gaps = 11/187 (5%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V G + C + +P P + W P K + D TL +S +D G Y Sbjct: 587 VMAGTDVVVRCPVKTRPEPGLSWRIRGLAFDP-KTSRAKLQNDNSTLLLSGLTKDDAGSY 645 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQAD--NLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751 C+A N+AG+ ++V P + + + + +T + S I T Sbjct: 646 TCIARNNAGKDQKVTNIQVADPQKPTIISQSGFKSSHESDIEMTVTIGIQTTVLSGITLT 705 Query: 4752 IQWLREGALIPETP---DFQMIHEGNNAV-----LLIGNTYEEDTGTFTCRATTAAGQVE 4803 I G P+ + + G V L I N ++D G C A AAGQ Sbjct: 706 IICPTRGLPAPDVTWEMNNTNVRPGGRFVVQEGTLTIRNLVKQDQGNIRCVARNAAGQDT 765 Query: 4804 TSAKLVV 4810 ++KL V Sbjct: 766 ATSKLNV 772 Score = 41.9 bits (94), Expect = 0.012 Identities = 78/347 (22%), Positives = 129/347 (37%), Gaps = 51/347 (14%) Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV---LEILGTKTTDSGTYSCRATNKWG 3130 P D++M I+WF G E R G+ L I + GTY C+AT G Sbjct: 377 PDEDKAM-IQWFTEGGFYEIKRFQRYEDDVGIDDEGNLHIRSVGRFNEGTYQCKATRLAG 435 Query: 3131 Q---AEISVKLECVD-----KSKGQK---PR---FTTHIQNIEGLKDGQSAHFECTVVPV 3176 A ++K+ ++ +KG+ PR T + L G + +C V+ Sbjct: 436 ASSTAAFTLKILALNTPTILSAKGKASFGPRDADVTITVGTTVTLYKGTTLTIKCPVM-- 493 Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236 P + WY G+P+ + ++ +D Y EY C AYN+ Sbjct: 494 GKPTPTVYWYSQGRPIAVGKAVTIGNNLRIENIDKIYAL-----EYTCHAYNRRARTKES 548 Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296 + +N + L P +A R++ S+ +TPS + I T L Sbjct: 549 SVVN--------VLDLAPPIIAAERKVISVD------KTTPSMD-------ITIGTNLTV 587 Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGHRYRTFHDFGIVILDILYCYEENSGEY 3355 R P+ + W G P R + +D ++L L ++++G Y Sbjct: 588 MAGTDVVVRCPVKTRPEPGLSWRIRGLAFDPKTSRAKLQNDNSTLLLSGL--TKDDAGSY 645 Query: 3356 ECVATNKLGRDSTKANLKCT--SKENLILDSQLPRGMEGGLEKLQTL 3400 C+A N G+D N++ K +I S E +E T+ Sbjct: 646 TCIARNNAGKDQKVTNIQVADPQKPTIISQSGFKSSHESDIEMTVTI 692 Score = 40.7 bits (91), Expect = 0.028 Identities = 111/493 (22%), Positives = 181/493 (36%), Gaps = 83/493 (16%) Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250 +G I ++CR P D M ++WF G + RF+ Y D V +D D G Sbjct: 366 KGSEITVKCRT-PDEDKAM-IQWFTEGGFYEI-KRFQRYEDD--VGID-------DEGNL 413 Query: 1251 TVRAVNHLGSA-HTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVRE-DITVM 1308 +R+V + R+ S T A+ +L + + R+ D+T+ Sbjct: 414 HIRSVGRFNEGTYQCKATRLAGASSTAAFTLKILALNTPTILSAKGKASFGPRDADVTIT 473 Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368 + +GT + ++C + +G T V W+ G+PI G Sbjct: 474 VGT-------TVTLYKGTTLTIKCPV--MGKPTPTVYWYSQGRPIAVGKAVTIGNNLRIE 524 Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428 +D +Y + YTC A N+ S + V+ I+ ++ K+ ++ Sbjct: 525 NID--KIYALE---YTCHAYNRRARTKESSVVNVLDLAPPIIAAE-----RKVISVD--- 571 Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG---Q 1485 K T +D +TI V+ G V C ++ + L W G Sbjct: 572 --KTTPSMD--ITIGTNL--------TVMAGTDVVVRCPVKTRPEPGL--SWRIRGLAFD 617 Query: 1486 PVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRS 1545 P T R + +D + L L +D+G YTC A N G D+ + T V Sbjct: 618 PKT--SRAKLQNDNSTLLLS--GLTKDDAGSYTCIARNNAGKDQ-------KVTNIQVAD 666 Query: 1546 TQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVS 1605 Q + Q H +D+ E+T I TT L + + R +P Sbjct: 667 PQKPTIISQ----SGFKSSHESDI--EMTVTIGIQTTVLSGITL----TIICPTRGLPAP 716 Query: 1606 DATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG-EAVTS 1664 D T W NN ++ G RF L I + + +D G C A NA G + TS Sbjct: 717 DVT----WEMNNTNVRPGGRFVVQEG----TLTIRNLVKQDQGNIRCVARNAAGQDTATS 768 Query: 1665 GIAIVHSKKSIYL 1677 + ++ + L Sbjct: 769 KLNVIDCYSEVSL 781 Score = 40.7 bits (91), Expect = 0.028 Identities = 81/364 (22%), Positives = 140/364 (38%), Gaps = 63/364 (17%) Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200 ++ G++ R T Q++ + + + C +V P + W N Q +R + R+ Sbjct: 957 IEDGDGEEARITIG-QDLR-VVEKMNVRIHCPIVGFPKP--VVTWTRNNQDVRSNARLFV 1012 Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260 + ++++ T D+G+Y+C A N GED + ++ + S I Sbjct: 1013 DPNTNDLLINNILTS--DTGQYICSAVNPIGED----------EKSSFISIISEASAEII 1060 Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPV-DDPDLKVEWF 3319 R SL + + P T I + +++ G + PV P + W Sbjct: 1061 RGNASLVTSSNRKPVT---------VVIGNSLEVLSGTDVTI---VCPVRGTPSPFIFWR 1108 Query: 3320 YNGKKLPHGHRYRTF----HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375 ++G ++ G F + G IL I ++ SG YECVA+N G D +++ Sbjct: 1109 HDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGSYECVASNVGGADRVATSIQ-- 1166 Query: 3376 SKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREG 3435 ++++Q P +E ++LQ+L+D T + L G Sbjct: 1167 -----VIEAQQP-VIEFISKRLQSLKD----------------LSAVTATIGTTITLLAG 1204 Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLC 3495 A + T P W NG+ L+ G R D L I DSG+Y C Sbjct: 1205 --AKLVLQCPSTGVPLPSTSWSLNGEPLEKGGR----ADLRGTELVIPAVAGVDSGKYQC 1258 Query: 3496 RAYN 3499 A N Sbjct: 1259 TASN 1262 Score = 40.7 bits (91), Expect = 0.028 Identities = 88/359 (24%), Positives = 138/359 (38%), Gaps = 60/359 (16%) Query: 1611 VEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669 V W NN+ ++S +R F + N + I + L D+G Y C A+N +GE S + Sbjct: 995 VTWTRNNQDVRSNARLFVDPNTNDLL---INNILTSDTGQYICSAVNPIGEDEKSSFISI 1051 Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729 S+ S + + + N+ T V+ + + D+ + Sbjct: 1052 ISEASAEIIRGNASLVTSSNRKPVT-----------VVIGNSLEVLSGTDVTI------- 1093 Query: 1730 FEARLIPV-GDPKLRVEWLRNGVPIEASNR----LTTMHDFGYVALNMKYVNPEDSGTYT 1784 + PV G P + W +G+ I + L + G L + V + SG+Y Sbjct: 1094 ----VCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGSYE 1149 Query: 1785 CRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAP 1844 C A N +G A +T S+Q+ + ++ I S R Q +D+ Sbjct: 1150 CVASN-VGGADRVAT-------SIQVIEAQQPVIEFI-----SKRLQSLKDLSAVTATIG 1196 Query: 1845 RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAAL 1904 IT L G KL +C P P+ W NG+ L+ G R D L Sbjct: 1197 TTITLLAG-AKLV------LQCPSTGVPLPS--TSWSLNGEPLEKGGR----ADLRGTEL 1243 Query: 1905 DILTVYGEDSGEYTCKAIN--NLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961 I V G DSG+Y C A N L S + + +K IR + + L +I L D Sbjct: 1244 VIPAVAGVDSGKYQCTASNVIALDSRASDVTVRDPTKPK-IRGAPKDMDLFEIMKLSVD 1301 Score = 39.5 bits (88), Expect = 0.065 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 4/85 (4%) Query: 77 IFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQI 136 I ++ R + N + + G P PVV+WTR V N + + T D LLI I Sbjct: 969 IGQDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQD-VRSNA-RLFVDPNTND--LLINNI 1024 Query: 137 GPGDEGEYTCTARNQYGEAICSVYI 161 D G+Y C+A N GE S +I Sbjct: 1025 LTSDTGQYICSAVNPIGEDEKSSFI 1049 Score = 39.1 bits (87), Expect = 0.086 Identities = 53/220 (24%), Positives = 87/220 (39%), Gaps = 32/220 (14%) Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796 +G P V W G PI +T ++ L ++ ++ + YTC A N Sbjct: 493 MGKPTPTVYWYSQGRPIAVGKAVTIGNN-----LRIENIDKIYALEYTCHAYNRRARTKE 547 Query: 1797 SSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856 SS + V L L +A +K+ ++ ++ D+ + N + Sbjct: 548 SSVVNV-----LDLAPPIIAAERKVISVDKTTPSM---DITIGTNLT------------V 587 Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSG 1915 G C ++ P+P + W G R + ND L LT +D+G Sbjct: 588 MAGTDVVVRCPVKTRPEPGL--SWRIRGLAFDPKTSRAKLQNDNSTLLLSGLTK--DDAG 643 Query: 1916 EYTCKAINNLG--QAVSSIRLNVQSKESIIRDSQHESALE 1953 YTC A NN G Q V++I++ K +II S +S+ E Sbjct: 644 SYTCIARNNAGKDQKVTNIQVADPQKPTIISQSGFKSSHE 683 Score = 38.7 bits (86), Expect = 0.11 Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900 V E VR C + PK + W RN + + S R D L I + D+G Sbjct: 975 VVEKMNVRIHCPIVGF--PKPVVTWTRNNQDVRSNARL--FVDPNTNDLLINNILTSDTG 1030 Query: 3901 EYICRAVNDFGEDFTKATIS 3920 +YIC AVN GED + IS Sbjct: 1031 QYICSAVNPIGEDEKSSFIS 1050 Score = 36.3 bits (80), Expect = 0.61 Identities = 48/214 (22%), Positives = 78/214 (36%), Gaps = 34/214 (15%) Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL---TTGARLKSTFDFGLVTLSINSLRND 2710 ++ G V + V+ R +P L W G+ T+ A+L++ TL ++ L D Sbjct: 587 VMAGTDVVVRCPVKTRPEPGLS--WRIRGLAFDPKTSRAKLQNDNS----TLLLSGLTKD 640 Query: 2711 DSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXX 2770 D+G YTC A N G+ +I++ D P + + G Sbjct: 641 DAGSYTCIARNNAGKDQKVTNIQVADPQ-------KPTIISQSGFKSSHESDIEMTVTIG 693 Query: 2771 XXXXVFISHLNNIVCKEGDNIHFECNVEPSRD-PTLKIEWFFNNKPLPSGTRYKSTHDFS 2829 V I+C P+R P + W NN + G R+ Sbjct: 694 IQTTVLSGITLTIIC-------------PTRGLPAPDVTWEMNNTNVRPGGRFVVQEG-- 738 Query: 2830 YVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 +L I + ++D G C A N+ G T + L Sbjct: 739 --TLTIRNLVKQDQGNIRCVARNAAGQDTATSKL 770 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 2/86 (2%) Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787 +D+ V E + I KP + W R + ++ + N LLI N D Sbjct: 971 QDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQDVRSNA--RLFVDPNTNDLLINNILTSD 1028 Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813 TG + C A G+ E S+ + + S+ Sbjct: 1029 TGQYICSAVNPIGEDEKSSFISIISE 1054 Score = 35.1 bits (77), Expect = 1.4 Identities = 17/62 (27%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 V W ++ + V +++R+ F + L I ++ D G Y C A N IG+ S+ ++I+ Sbjct: 995 VTWTRNNQDVRSNARL--FVDPNTNDLLINNILTSDTGQYICSAVNPIGEDEKSSFISII 1052 Query: 1003 TK 1004 ++ Sbjct: 1053 SE 1054 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 2/63 (3%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P + W +N + + ARL D L IN++ D+G Y C A N +GE ++ Sbjct: 991 PKPVVTWTRNNQDVRSNARL--FVDPNTNDLLINNILTSDTGQYICSAVNPIGEDEKSSF 1048 Query: 2732 IKI 2734 I I Sbjct: 1049 ISI 1051 Score = 33.9 bits (74), Expect = 3.2 Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 36/223 (16%) Query: 3694 PPRFTVEIKDN-----IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748 PP V+ KD+ + +G + CR P D M I WF G + + Sbjct: 346 PPAIMVKCKDSDCGSSVWSVKGSEITVKCRT-PDEDKAM-IQWFTEGGFYEIKRFQRYED 403 Query: 3749 DFGFIA---LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSG 3805 D G L I + + G Y C+AT G A++TA T +L P +S Sbjct: 404 DVGIDDEGNLHIRSVGRFNEGTYQCKATRLAG-ASSTAAFTLK-----ILALNTPTILSA 457 Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865 +G+ S P++ + T +T K T + +C V K P + W Sbjct: 458 -------KGKASFGPRDADVTITVGTTVTLYKGTT------LTIKCPVMGKPTP--TVYW 502 Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908 Y G+ + G ++ ++D +Y EY C A N Sbjct: 503 YSQGRPIAVGKAVTIGNNLRIENIDKIYAL-----EYTCHAYN 540 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Query: 3604 SRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663 SR K ND ++L G+ + DAG YTC A N G+ +QV Q + Q S Sbjct: 621 SRAKLQNDNSTLLLS--GLTKDDAGSYTCIARNNAGKDQKVTNIQVADPQKPTIISQ--S 676 Query: 3664 HFKSGTESIQKLEETL 3679 FKS ES ++ T+ Sbjct: 677 GFKSSHESDIEMTVTI 692 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 8/89 (8%) Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL--SVY 1376 ++ VE NV + C + VG V W N + +++ R D DLL ++ Sbjct: 972 DLRVVEKMNVRIHCPI--VGFPKPVVTWTRNNQDVRSNARLF----VDPNTNDLLINNIL 1025 Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 D+G Y C A N +GE S + +I++ Sbjct: 1026 TSDTGQYICSAVNPIGEDEKSSFISIISE 1054 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 6/75 (8%) Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI--QDSGEYTCRAVSATGVA 720 VG P + W +N Q + +++R +F + D+L NI D+G+Y C AV+ G Sbjct: 988 VGFPKPVVTWTRNNQDVRSNAR---LFVDPNTN-DLLINNILTSDTGQYICSAVNPIGED 1043 Query: 721 ETKAVLHVTPRATIE 735 E + + + A+ E Sbjct: 1044 EKSSFISIISEASAE 1058 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 7/87 (8%) Query: 2915 IPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLV 2974 I + L +G L ++ V K P + WY G+ + G + ++ +D + Sbjct: 472 ITVGTTVTLYKGTTLTIKCPVMGKPTPT--VYWYSQGRPIAVGKAVTIGNNLRIENIDKI 529 Query: 2975 DVYERDSGIYTCKAYNKRGEAFTSSTV 3001 E YTC AYN+R SS V Sbjct: 530 YALE-----YTCHAYNRRARTKESSVV 551 Score = 32.7 bits (71), Expect = 7.5 Identities = 17/78 (21%), Positives = 36/78 (46%), Gaps = 2/78 (2%) Query: 2115 LTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYT 2174 +T ++L+ ++ + + P + W N Q +R+ R + + ++ + T Sbjct: 967 ITIGQDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQDVRSNARLFVDPNTNDLLINNILT 1026 Query: 2175 YAEDSGTYMCKATNKLGE 2192 D+G Y+C A N +GE Sbjct: 1027 --SDTGQYICSAVNPIGE 1042 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 2/57 (3%) Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 VG P V W RN + + ++R+ D + I+++ D G Y+C A N +GE Sbjct: 988 VGFPKPVVTWTRNNQDVRSNARLFV--DPNTNDLLINNILTSDTGQYICSAVNPIGE 1042 >SB_10900| Best HMM Match : I-set (HMM E-Value=0) Length = 1642 Score = 80.2 bits (189), Expect = 4e-14 Identities = 97/393 (24%), Positives = 145/393 (36%), Gaps = 43/393 (10%) Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI-KNSPDFQIHTFSTKSILIIR 4471 FTK+ F+ Q FE + G P W ++ + K + D + ++ S L I Sbjct: 29 FTKQPSSQLGFKGLQVEFECQVSGIANPSYYWIKDGTNVTKGTQDVK----NSISSLTIS 84 Query: 4472 QVFVEDSAVFAAVAENRGG-TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 + D+ + VA T +A L V QG P T + GQ Sbjct: 85 GLKFTDAGQYVCVATGIATLTTSTAATLTV-----QGS-----PDITQGPTGTSPHVGQE 134 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 T V W QP R+ G +L+I + D+G Y C+ N Sbjct: 135 AIFHCIATANPSPSVSWTNPFD--QPINRSGRFTVYGNGSLVISDVKKADTGYYTCIVSN 192 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650 S G A+ A+ V D P A P ++ EG I F C G P Sbjct: 193 SFGSAKAFAQLTVL-----DAP--------AAPSFTTTPTNQTAREGSDITFYCMASGVP 239 Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710 PT+ W+K +I ++ + A +RI P D+G Y C A NS G L Sbjct: 240 TPTITWHKVGGVILSNRTDKPRPGA----IRIQSVIPSDDGSYVCEAINSEGTKRADVYL 295 Query: 4711 KVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQW-LREGALIPETPDFQ 4768 ++ + P T D+V E + + P++ W L GA+ T Sbjct: 296 RI------EGFPRFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWILPSGAIATVTSPAS 349 Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 + N L+IGN E + G + C A + G+ Sbjct: 350 RVQVLANHTLVIGNATESEYGEYVCVAKNSVGE 382 Score = 72.9 bits (171), Expect = 6e-12 Identities = 79/321 (24%), Positives = 123/321 (38%), Gaps = 48/321 (14%) Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319 L P ++P + +G +F+ Q+SG P W K+G + + ++ Sbjct: 21 LAPCLSQSFTKQPSSQLGFKGLQVEFECQVSGIANPSYYWIKDGTNVTKGTQD---VKNS 77 Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRET 379 ++L + + +D+G Y C+ T G + + T + + Q S IT Q T Sbjct: 78 ISSLTISGLKFTDAGQYV--------CVAT-GIATLTTSTAATLTVQGSPDIT---QGPT 125 Query: 380 EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439 + ++A+ F C T P P V+W N Sbjct: 126 GTSPHVGQEAI--------------------FHCIATANPSPSVSW---TNPFDQPINRS 162 Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499 GN +L+I++V +D+G TC+ N G +L V++ AP F + Sbjct: 163 GRFTVYGNGSLVISDVKKADTGYYTCIVSNSFGSAKAFAQLTVLDAP--AAPSFTTTPTN 220 Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKASDA 558 REG + A G PTP ITW K G I+ N TD + I SD Sbjct: 221 QTAREGSDITFYCMASGVPTPTITWHKVGGVILSN-----RTDKPRPGAIRIQSVIPSDD 275 Query: 559 AWYQCTAQNVAGSTATRARLY 579 Y C A N G+ RA +Y Sbjct: 276 GSYVCEAINSEGT--KRADVY 294 Score = 71.3 bits (167), Expect = 2e-11 Identities = 58/197 (29%), Positives = 82/197 (41%), Gaps = 19/197 (9%) Query: 388 KALAPQFVKVCQ-DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446 + + P +KV ++ V G R DC+ G P P +TW + + H + + Sbjct: 472 RVIVPPSIKVPPTNQSVALGATARLDCQADGDPPPLMTWETSQGSVIGQARHTV----AA 527 Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506 N L+IT T D+G +TC A N +G T + L + + P FV+ S + +G Sbjct: 528 NGTLIITMATAGDTGWLTCTATNAAGSTVKKAYLTISD-----VPVFVQLPSHQTLVKGN 582 Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS----TLDIPRAKASDAAWYQ 562 + L RA P ITW K + L+ T G S L D Y Sbjct: 583 AITLPCRATAADAPVITWFKAD----QSGALQQLTSSGVSQANGDLSFASVTRQDRGMYA 638 Query: 563 CTAQNVAGSTAT-RARL 578 C A N AG T T RA L Sbjct: 639 CQACNAAGCTMTPRASL 655 Score = 68.1 bits (159), Expect = 2e-10 Identities = 70/263 (26%), Positives = 101/263 (38%), Gaps = 28/263 (10%) Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570 IVPPS + N +V G RLD + G P + W + V R+ + T Sbjct: 474 IVPPSIKVPPTNQSVALGATARLDCQADGDPPPLMTWETSQGSVIGQARHTVAANG---T 530 Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVS-LPATKDKPKPQTKAANAPPEIIEPL 4629 L+I A D+G C A N+AG A +S +P P QT Sbjct: 531 LIITMATAGDTGWLTCTATNAAGSTVKKAYLTISDVPVFVQLPSHQT------------- 577 Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689 + +G AI C+ P + W+K D+ + + L + +D Sbjct: 578 ----LVKGNAITLPCRATAADAPVITWFKADQSGALQQLTSSGVSQANGDLSFASVTRQD 633 Query: 4690 EGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748 G Y C A N+AG +T A L V N P D+ V +G+ A+ S Sbjct: 634 RGMYACQACNAAGCTMTPRASLNVLY-----NPLFPVPPPDVGVIQGEDAKLMCAPDSNP 688 Query: 4749 KPTIQWLR-EGALIPETPDFQMI 4770 TI W R +G +P T Q+I Sbjct: 689 PATISWSRPDGTALPGTGYEQVI 711 Score = 67.7 bits (158), Expect = 2e-10 Identities = 76/321 (23%), Positives = 122/321 (38%), Gaps = 45/321 (14%) Query: 252 ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311 ++T +L P I Q P + G +A F + NP P V+W + IN + Sbjct: 104 LTTSTAATLTVQGSPDITQGPTGTSPHVGQEAIFHCIATANPSPSVSWTNPFDQPINRSG 163 Query: 312 HEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYI 371 T + + +L + + +K+D+G+YT CIV++ + +++ Q Sbjct: 164 R--FTVYGNGSLVISDVKKADTGYYT--------CIVSNSF----GSAKAFAQ------- 202 Query: 372 TDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ 431 + + + AP F ++ EG F C +G P P +TW Sbjct: 203 -----------LTVLDAPAAPSFTTTPTNQTAREGSDITFYCMASGVPTPTITWHKVGGV 251 Query: 432 IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491 I + K G A+ I +V SD G C A N G L + P Sbjct: 252 ILSNRTDK---PRPG--AIRIQSVIPSDDGSYVCEAINSEGTKRADVYLRI-----EGFP 301 Query: 492 KFVERFSTLNVREGEPVVLNARAVGTPTPRITW--QKDGVPIIPNPELRIHTDGGASTLD 549 +F S + E V L+ G PTP ++W + + +P R+ TL Sbjct: 302 RFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWILPSGAIATVTSPASRVQVLAN-HTLV 360 Query: 550 IPRAKASDAAWYQCTAQNVAG 570 I A S+ Y C A+N G Sbjct: 361 IGNATESEYGEYVCVAKNSVG 381 Score = 66.5 bits (155), Expect = 5e-10 Identities = 106/423 (25%), Positives = 155/423 (36%), Gaps = 62/423 (14%) Query: 4393 KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK 4452 KA Q V++ P PS FT E F G P P I W++ I Sbjct: 198 KAFAQLTVLDAPAAPS----FTTTPTNQTAREGSDITFYCMASGVPTPTITWHKVGGVIL 253 Query: 4453 NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512 ++ + + + I+ V D + A N GT + L +E G Sbjct: 254 SNRTDKPRPGAIR----IQSVIPSDDGSYVCEAINSEGTKRADVYLRIE--------GF- 300 Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV----QPDIRNKILEEDGT 4568 P FTL+ +V V+LD V G V W+ + P R ++L Sbjct: 301 -PRFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWILPSGAIATVTSPASRVQVL---AN 356 Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628 +TL+I A + G+Y CVA NS GE + VS+ P ++ N I P Sbjct: 357 HTLVIGNATESEYGEYVCVAKNSVGEKT--RKVTVSILTV---PSFNSQLLN----ISRP 407 Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688 ++D + C G P P W G K++ SRT +L ++ Sbjct: 408 IRDNVT-------IMCPSRGNPSPHHLWTFGGKILS------QSRTLSLVSLNVT----- 449 Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748 + G Y C NS G ++ L+V P P + V G A+ Q Sbjct: 450 NRGYYTCHLNNSMGSAELSFFLRVIVPPSIK-----VPPTNQSVALGATARLDCQADGDP 504 Query: 4749 KPTIQW-LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807 P + W +G++I + N L+I DTG TC AT AAG A Sbjct: 505 PPLMTWETSQGSVIGQARHTVAA----NGTLIITMATAGDTGWLTCTATNAAGSTVKKAY 560 Query: 4808 LVV 4810 L + Sbjct: 561 LTI 563 Score = 60.1 bits (139), Expect = 4e-08 Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 8/134 (5%) Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504 S + L + ++ +++ G TC N G L VI + P + +V Sbjct: 436 SQSRTLSLVSLNVTNRGYYTCHLNNSMGSAELSFFLRVIVPPSIKVPP-----TNQSVAL 490 Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 G L+ +A G P P +TW+ +I HT TL I A A D W CT Sbjct: 491 GATARLDCQADGDPPPLMTWETSQGSVIGQAR---HTVAANGTLIITMATAGDTGWLTCT 547 Query: 565 AQNVAGSTATRARL 578 A N AGST +A L Sbjct: 548 ATNAAGSTVKKAYL 561 Score = 58.4 bits (135), Expect = 1e-07 Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 6/170 (3%) Query: 360 ESYVQDQRSQYITDTQQRETEERIEISEKALA-PQFVKVCQDRDVTEGKMTRFDCRVTGR 418 +S + Y+ + E +R ++ + P+F D E + DC V G Sbjct: 268 QSVIPSDDGSYVCEAINSEGTKRADVYLRIEGFPRFTLSPSDVVAPEFSEVKLDCLVAGD 327 Query: 419 PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478 P P V+W + I + V NH L+I N T S+ G CVA+N GE + Sbjct: 328 PTPSVSWILPSGAIATVTSPASRVQVLANHTLVIGNATESEYGEYVCVAKNSVGEKTRKV 387 Query: 479 RLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528 ++++ P F + ++ + V + + G P+P W G Sbjct: 388 TVSIL-----TVPSFNSQLLNISRPIRDNVTIMCPSRGNPSPHHLWTFGG 432 Score = 51.2 bits (117), Expect = 2e-05 Identities = 93/395 (23%), Positives = 136/395 (34%), Gaps = 54/395 (13%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P FT E + + + G+P P + W P I T ++ + + Sbjct: 301 PRFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWIL--------PSGAIATVTSPASRV- 351 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP-PSFTLTAQNVNVTSGQ 4529 QV + V E+ G C A V EK R+ I+ PSF N++ Sbjct: 352 -QVLANHTLVIGNATESEYGEYVCVAKNSVGEKTRKVTVSILTVPSFNSQLLNISRPIRD 410 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589 V + G W GK IL + T +L+ L + G Y C Sbjct: 411 NVTIMCPSRGNPSPHHLWTFGGK---------ILSQSRTLSLVSLNV--TNRGYYTCHLN 459 Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649 NS G A V +P P I P ++ VA G C+ G Sbjct: 460 NSMGSAELSFFLRVIVP----------------PSIKVPPTNQSVALGATARLDCQADGD 503 Query: 4650 PLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708 P P + W +I +++ A TL I+ A D G C A N+AG A Sbjct: 504 PPPLMTWETSQGSVIGQARH----TVAANGTLIITMATAGDTGWLTCTATNAAGSTVKKA 559 Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR---EGALIPETP 4765 L ++ LP+ L +G + T+ P I W + GAL T Sbjct: 560 YLTISDVPVFVQLPSHQTL-----VKGNAITLPCRATAADAPVITWFKADQSGALQQLTS 614 Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 G+ L + +D G + C+A AAG Sbjct: 615 SGVSQANGD---LSFASVTRQDRGMYACQACNAAG 646 Score = 50.8 bits (116), Expect = 3e-05 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 4/112 (3%) Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312 S E+ L + PP I P N + GA A+ Q G+P P +TW + +I +H Sbjct: 464 SAELSFFLRVIVPPSIKVPPTNQSVALGATARLDCQADGDPPPLMTWETSQGSVIGQARH 523 Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364 T + TL + D+G T A N G V YL + S +VQ Sbjct: 524 ---TVAANGTLIITMATAGDTGWLTCTATNAAGSTVKKAYLTI-SDVPVFVQ 571 Score = 49.6 bits (113), Expect = 6e-05 Identities = 50/178 (28%), Positives = 76/178 (42%), Gaps = 15/178 (8%) Query: 4636 EGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694 +G +EF C++ G P+ W K G + K ++ + S ++ L IS D G Y Sbjct: 40 KGLQVEFECQVSGIANPSYYWIKDGTNVTKGTQDVKNSISS----LTISGLKFTDAGQYV 95 Query: 4695 CVAYNSAGRVT-VAAKLKVT-QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752 CVA A T AA L V PD +P + GQ A F T+ P++ Sbjct: 96 CVATGIATLTTSTAATLTVQGSPDITQGPTGTSP------HVGQEAIFHCIATANPSPSV 149 Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 W P + GN + L+I + + DTG +TC + + G + A+L V Sbjct: 150 SWTNPFDQ-PINRSGRFTVYGNGS-LVISDVKKADTGYYTCIVSNSFGSAKAFAQLTV 205 Score = 45.6 bits (103), Expect = 0.001 Identities = 45/160 (28%), Positives = 64/160 (40%), Gaps = 13/160 (8%) Query: 3073 IPTGDQSMVIEWFYN-GKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131 I T + S + W + I S R TVY G +V+ K D+G Y+C +N +G Sbjct: 140 IATANPSPSVSWTNPFDQPINRSGRF-TVYGNGSLVIS--DVKKADTGYYTCIVSNSFGS 196 Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191 A+ +L +D P FTT N + ++G F C V P I W+ G Sbjct: 197 AKAFAQLTVLDAPAA--PSFTTTPTN-QTAREGSDITFYCMASGVPTP--TITWHKVGGV 251 Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 + + K + I D G YVC A N G Sbjct: 252 ILSNRTDKPRPG----AIRIQSVIPSDDGSYVCEAINSEG 287 Score = 45.2 bits (102), Expect = 0.001 Identities = 58/265 (21%), Positives = 96/265 (36%), Gaps = 20/265 (7%) Query: 86 GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145 G A F NP+P VSWT P + S R+ G+ SL+I + D G YT Sbjct: 132 GQEAIFHCIATANPSPSVSWTN---PFDQPINRSGRFTVY-GNGSLVISDVKKADTGYYT 187 Query: 146 CTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQ 203 C N +G +A + + R S+ + T + Sbjct: 188 CIVSNSFGSAKAFAQLTVLDAPAAPSFTTTPTNQTAREGSDITFYCMASGVPTPTITWHK 247 Query: 204 TQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSF-RESITKRYVGESDVQISTEIDRSLGP 262 V +N TD ++ + + S+ E+I +DV + E Sbjct: 248 VGGVILSNRTDKPRPGAIRIQSVIPS--DDGSYVCEAINSEGTKRADVYLRIE------- 298 Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF--KNGQRLINSNKHEIITTHNH 320 P+ P + E ++ + ++G+P P V+W + S + NH Sbjct: 299 -GFPRFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWILPSGAIATVTSPASRVQVLANH 357 Query: 321 TTLRVRNTQKSDSGHYTLLAENPNG 345 TL + N +S+ G Y +A+N G Sbjct: 358 -TLVIGNATESEYGEYVCVAKNSVG 381 Score = 43.2 bits (97), Expect = 0.005 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 6/97 (6%) Query: 69 PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128 P+ P F N +G + F G PTP ++W K ++ N+ ++ Sbjct: 209 PAAPSFTTTPTNQTAREGSDITFYCMASGVPTPTITW-HKVGGVILSNR-----TDKPRP 262 Query: 129 VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165 ++ I+ + P D+G Y C A N G VY++ EG Sbjct: 263 GAIRIQSVIPSDDGSYVCEAINSEGTKRADVYLRIEG 299 Score = 41.5 bits (93), Expect = 0.016 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 5/91 (5%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP + N A G A+ + + G+P P+++W + ++ ++++ N + Sbjct: 476 PPSIKVPPTNQSVALGATARLDCQADGDPPPLMTWETSQGSVIGQARHTVAANG-----T 530 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161 L+I GD G TCTA N G + Y+ Sbjct: 531 LIITMATAGDTGWLTCTATNAAGSTVKKAYL 561 Score = 40.7 bits (91), Expect = 0.028 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 12/156 (7%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753 PP V N V G DC+ + GDP + W + G HT+ G Sbjct: 476 PPSIKVP-PTNQSVALGATARLDCQAD--GDPPPLMTW-ETSQGSVIGQARHTVAANG-- 529 Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQG---MSGEKIKE 3810 L I A D G TC ATN GS A +T S D+ + QLP + G I Sbjct: 530 TLIITMATAGDTGWLTCTATNAAGSTVKKAYLTIS---DVPVFVQLPSHQTLVKGNAITL 586 Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846 R +DAP + + Q+ S V ++ G Sbjct: 587 PCRATAADAPVITWFKADQSGALQQLTSSGVSQANG 622 Score = 39.5 bits (88), Expect = 0.065 Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 15/127 (11%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD--GQ 3165 L I G K TD+G Y C AT G A ++ +G P T Q G GQ Sbjct: 81 LTISGLKFTDAGQYVCVAT---GIATLTTSTAATLTVQG-SPDIT---QGPTGTSPHVGQ 133 Query: 3166 SAHFECTVVPVDDPDMKIEWYHN-GQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 A F C + +P + W + QP+ S R + V+ D+ + D+G Y C Sbjct: 134 EAIFHC--IATANPSPSVSWTNPFDQPINRSGRFTVYGNGSLVISDV---KKADTGYYTC 188 Query: 3225 RAYNKYG 3231 N +G Sbjct: 189 IVSNSFG 195 Score = 38.7 bits (86), Expect = 0.11 Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 3/86 (3%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEW-FHNGKPLLTGSRVKTINDFGFVI 3616 P FT +PSD++ E S +C + D + V W +G S + Sbjct: 301 PRFTLSPSDVVAPEFSEVKLDC--LVAGDPTPSVSWILPSGAIATVTSPASRVQVLANHT 358 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEAT 3642 L IG + + G Y C A N GE T Sbjct: 359 LVIGNATESEYGEYVCVAKNSVGEKT 384 Score = 38.3 bits (85), Expect = 0.15 Identities = 69/332 (20%), Positives = 124/332 (37%), Gaps = 35/332 (10%) Query: 1090 NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV------ETRSSIDT 1143 NR + +G +L I+ V+ D+G YT + N+ G A+ A +TV + ++ T Sbjct: 160 NRSGRFTVYGNGSLVISDVKKADTGYYTCIVSNSFGSAKAFAQLTVLDAPAAPSFTTTPT 219 Query: 1144 SSIHRGLYEKTRHIEESKFVEPMYQIEEIS---------KSKPVFVQPLSNPPPVSEGKN 1194 + R + T + S P ++ K +P ++ + + P +G Sbjct: 220 NQTAREGSDITFYCMASGVPTPTITWHKVGGVILSNRTDKPRPGAIR-IQSVIPSDDGSY 278 Query: 1195 IHLECRLE--PMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTV 1252 + E D +R+E F T+ +F V LD + A + Sbjct: 279 VCEAINSEGTKRADVYLRIEGFPR---FTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWI 335 Query: 1253 RAVNHLGSAHTSAI-VRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP 1311 + + + A V+V+ +V E + + + K + ++++ P Sbjct: 336 LPSGAIATVTSPASRVQVLANHTLVIGNATESEYGEYVCVAKNSVGEKTRKVTVSILTVP 395 Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371 F+ L NI NV + C + G+ + W GK + L Sbjct: 396 SFNSQLLNISRPIRDNVTIMCPSR--GNPSPHHLWTFGGKILSQSR-----------TLS 442 Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 L+S+ + G YTC N +G A S LRVI Sbjct: 443 LVSLNVTNRGYYTCHLNNSMGSAELSFFLRVI 474 Score = 37.5 bits (83), Expect = 0.26 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 4/61 (6%) Query: 943 VEWLKD-GRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 V W +P+ S R T + G +L I V D G+YTC N+ G A A LT+ Sbjct: 149 VSWTNPFDQPINRSGRFTVY---GNGSLVISDVKKADTGYYTCIVSNSFGSAKAFAQLTV 205 Query: 1002 V 1002 + Sbjct: 206 L 206 Score = 37.1 bits (82), Expect = 0.35 Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 6/102 (5%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P FTTTP++ E S F C V + + W G +L+ K + Sbjct: 212 PSFTTTPTNQTAREGSDITFYCMASGVPTPT--ITWHKVGGVILSNRTDKPRPG----AI 265 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659 I V D G Y C+A N G L+++G L P Sbjct: 266 RIQSVIPSDDGSYVCEAINSEGTKRADVYLRIEGFPRFTLSP 307 Score = 36.3 bits (80), Expect = 0.61 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR-LKSTFDFGLVTLSINSLRNDDSGI 2714 +G V E QV +P+ W K+G +T G + +K++ +L+I+ L+ D+G Sbjct: 40 KGLQVEFECQVSGIANPSYY--WIKDGTNVTKGTQDVKNSIS----SLTISGLKFTDAGQ 93 Query: 2715 YTCKATNLLGEAVSTAS 2731 Y C AT + STA+ Sbjct: 94 YVCVATGIATLTTSTAA 110 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 7/95 (7%) Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902 AP F T T EG + C P P + W+ G V+ S RT Sbjct: 211 APSFTTTPTNQTA-REGSDITFYCMASGVPTPT--ITWHKVGGVILSN---RTDKPRP-G 263 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 A+ I +V D G Y C+AIN+ G + + L ++ Sbjct: 264 AIRIQSVIPSDDGSYVCEAINSEGTKRADVYLRIE 298 Score = 36.3 bits (80), Expect = 0.61 Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 9/126 (7%) Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175 +D G+Y C A N G V L + +G PRFT ++ + +C V Sbjct: 273 SDDGSYVCEAINSEGTKRADVYL----RIEG-FPRFTLSPSDVVA-PEFSEVKLDCLV-- 324 Query: 3176 VDDPDMKIEW-YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234 DP + W +G ++ V L I + GEYVC A N GE Sbjct: 325 AGDPTPSVSWILPSGAIATVTSPASRVQVLANHTLVIGNATESEYGEYVCVAKNSVGEKT 384 Query: 3235 TRATIN 3240 + T++ Sbjct: 385 RKVTVS 390 Score = 36.3 bits (80), Expect = 0.61 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 90 KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149 K + + G+PTP VSW + + R + + +L+I + GEY C A+ Sbjct: 319 KLDCLVAGDPTPSVSWILPSGAIATVTSPASRV-QVLANHTLVIGNATESEYGEYVCVAK 377 Query: 150 NQYGE 154 N GE Sbjct: 378 NSVGE 382 Score = 35.9 bits (79), Expect = 0.80 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 8/92 (8%) Query: 1847 ITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAAL 1904 ITQ GPT S GQ A + C P P++ F+ + +SG R+ +G +L Sbjct: 120 ITQ--GPTGTSPHVGQEAIFHCIATANPSPSVSWTNPFDQPINRSG-RFTV---YGNGSL 173 Query: 1905 DILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 I V D+G YTC N+ G A + +L V Sbjct: 174 VISDVKKADTGYYTCIVSNSFGSAKAFAQLTV 205 Score = 35.9 bits (79), Expect = 0.80 Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 9/128 (7%) Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 +I V S G C ARN+ G T Q IE VV +E ST ++ Sbjct: 710 VIVGVQPSHVGDYKCSARNEYGSTGEQTIRLTIETRAVVTDFTMETSST--------DLV 761 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 GTP P +TW V + N + ++ L +P + +Y C A N Sbjct: 762 TCDVTGTPAPTVTWYLGNVKLPQNAKYPGYSVTRDDKLRLPIGTLKNNTFY-CNASNPHA 820 Query: 571 STATRARL 578 S A++ Sbjct: 821 SMRFLAKV 828 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 6/69 (8%) Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449 GQ A F C I +P+ V W ++ I S R T +G S+ IS V+ D G Y Sbjct: 132 GQEAIFHC--IATANPSPSVSWTNPFDQPINRSGRFTV---YGNGSLVISDVKKADTGYY 186 Query: 2450 MCRASNLLG 2458 C SN G Sbjct: 187 TCIVSNSFG 195 Score = 34.7 bits (76), Expect = 1.9 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 8/104 (7%) Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704 S +G ++ FE ++ + +P+ W+K+G ++ ++ T + SL + L Sbjct: 35 SQLGFKGLQVEFECQVSGIANPSYY--WIKDGTNV---TKGTQDVKNSISSLTISGLKFT 89 Query: 705 DSGEYTCRAVS-ATGVAETKAVLHV--TPRATIERTSQHPETLQ 745 D+G+Y C A AT T A L V +P T T P Q Sbjct: 90 DAGQYVCVATGIATLTTSTAATLTVQGSPDITQGPTGTSPHVGQ 133 Score = 34.3 bits (75), Expect = 2.5 Identities = 33/100 (33%), Positives = 42/100 (42%), Gaps = 8/100 (8%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P F + TA EG I F G PT I W K G I S+R T R G I + Sbjct: 212 PSFTTTPTNQTAREGSDITFYCMAS--GVPTPTITWHKVGGVI-LSNR-TDKPRPGAIRI 267 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT--PRATI 734 S+ D G Y C A+++ G L + PR T+ Sbjct: 268 Q--SVIPSDDGSYVCEAINSEGTKRADVYLRIEGFPRFTL 305 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 4643 SCKIVGKPLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701 +C + G P PTV WY G+ KL + +KY S T D+ LR+ ++ Y C A N Sbjct: 762 TCDVTGTPAPTVTWYLGNVKLPQNAKYPGYSVTRDD-KLRLPIGTLKNNTFY-CNASNPH 819 Query: 4702 GRVTVAAKL 4710 + AK+ Sbjct: 820 ASMRFLAKV 828 Score = 33.9 bits (74), Expect = 3.2 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 15/90 (16%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSR-DPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 F S L NI DN+ C PSR +P+ W F K L + S VSL+ Sbjct: 397 FNSQLLNISRPIRDNVTIMC---PSRGNPSPHHLWTFGGKIL------SQSRTLSLVSLN 447 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864 +T+ G YTC NS GSA S LR Sbjct: 448 VTNR-----GYYTCHLNNSMGSAELSFFLR 472 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 5/98 (5%) Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691 RV PP VP + + G + + + GDP + W + S+ +R T + Sbjct: 472 RVIVPPSIKVPPTNQSVALGATARLDCQAD--GDPPPLMTWETSQGSVIGQARHT-VAAN 528 Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729 G + + M + D+G TC A +A G KA L ++ Sbjct: 529 GTLIITMATAG--DTGWLTCTATNAAGSTVKKAYLTIS 564 Score = 33.9 bits (74), Expect = 3.2 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 6/93 (6%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P K P +Q S+ G A + + + GD + W V +R T N G + Sbjct: 477 PSIKVPPTNQ-SVALGATARLDCQAD--GDPPPLMTWETSQGSVIGQARHTVAAN-GTLI 532 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 +T+ T D G TC A NA G A LTI Sbjct: 533 ITM--ATAGDTGWLTCTATNAAGSTVKKAYLTI 563 Score = 33.9 bits (74), Expect = 3.2 Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 5/109 (4%) Query: 2616 WEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLK 2675 W AA + V + ++ + P+F L S+ LV+G + L + P Sbjct: 543 WLTCTATNAAGSTVKKAYLT--ISDVPVFV-QLPSHQTLVKGNAITLPCRATAADAP--V 597 Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724 I WFK + S LS S+ D G+Y C+A N G Sbjct: 598 ITWFKADQSGALQQLTSSGVSQANGDLSFASVTRQDRGMYACQACNAAG 646 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%) Query: 937 GDSTLRVEW-LKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995 GD T V W L G +S + L I + T + G Y C A N++G+ T Sbjct: 326 GDPTPSVSWILPSGAIATVTSPASRVQVLANHTLVIGNATESEYGEYVCVAKNSVGEKTR 385 Query: 996 SANLTIVT 1003 ++I+T Sbjct: 386 KVTVSILT 393 Score = 33.1 bits (72), Expect = 5.7 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 9/97 (9%) Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768 +G V F+C+V + +P+ W +G G++ N +L I + DAG+Y Sbjct: 40 KGLQVEFECQVSGIANPSYY--WIKDGTNVTKGTQ-DVKNSIS--SLTISGLKFTDAGQY 94 Query: 3769 TCRATNKWGSATTT-AKITCSAKRDIVLESQLPQGMS 3804 C AT T+T A +T DI +Q P G S Sbjct: 95 VCVATGIATLTTSTAATLTVQGSPDI---TQGPTGTS 128 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 7/84 (8%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 P F T P + + EG + F C V + W K G + +P A Sbjct: 212 PSFTTTPTN-QTAREGSDITFYCMASGVPTPT--ITWHKVGGVILSNRTDKPRPG----A 264 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGT 1527 + I +I D G Y C A+N GT Sbjct: 265 IRIQSVIPSDDGSYVCEAINSEGT 288 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 11/82 (13%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P+F + QG +AK NP +SW+R + Y EQ Sbjct: 661 PLFPVPPPDVGVIQGEDAKLMCAPDSNPPATISWSRPDGTALPGTGY-----EQ------ 709 Query: 132 LIKQIGPGDEGEYTCTARNQYG 153 +I + P G+Y C+ARN+YG Sbjct: 710 VIVGVQPSHVGDYKCSARNEYG 731 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/103 (26%), Positives = 38/103 (36%), Gaps = 7/103 (6%) Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026 +D P F T +QT+ + T F C + G P + W G +L P Sbjct: 206 LDAPAAPSFTTTPTNQTAREGSDIT-FYCMAS--GVPTPTITWHKVGGVILSNRTDKPRP 262 Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069 A+ V P D G Y+C A N G ++ G P Sbjct: 263 G----AIRIQSVIPSDDGSYVCEAINSEGTKRADVYLRIEGFP 301 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 6/71 (8%) Query: 1592 GQRAHFERRLIPVSDATLKVEWYHN-NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTY 1650 GQ A F I ++ + V W + ++P+ RFT N V D+ D+G Y Sbjct: 132 GQEAIFH--CIATANPSPSVSWTNPFDQPINRSGRFTVYGNGSLVISDVKKA---DTGYY 186 Query: 1651 TCRAINALGEA 1661 TC N+ G A Sbjct: 187 TCIVSNSFGSA 197 >SB_43700| Best HMM Match : SRCR (HMM E-Value=0) Length = 967 Score = 79.0 bits (186), Expect = 9e-14 Identities = 86/343 (25%), Positives = 139/343 (40%), Gaps = 38/343 (11%) Query: 4480 VFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV--PPSFTLTAQNVNVTSGQLVRLDTKV 4537 VFA V G C+A+ K G + PP T + N + +R T V Sbjct: 462 VFAPVKRTDQGFYTCTASQNAVTKISPGVSLTINFPPDTTFSPVMANQGNSATLRC-TVV 520 Query: 4538 TGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596 +G P + W+K+G R + +G L+ D G Y CVA+NS G R Sbjct: 521 SGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMGIGR 580 Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK--PLPTV 4654 S+ A K N PPE+ L+ + +EG C ++ P+ + Sbjct: 581 -------SIAAAK-------MTVNYPPEV--SLQSIVASEGGLATLRCSVIRSQPPVLSY 624 Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLKVT 4713 W K P+ + +S T L + + D+G Y C A NS G +++A+++ + Sbjct: 625 TWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSYTCEASNSVGNGISLASRMTI- 683 Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP---TIQWLREG-ALIPET-PDFQ 4768 + P +T + + EG A K + +P + W++E + P T P Sbjct: 684 ------HYPPVTSVSPLEAKEGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVS 737 Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET-SAKLVV 4810 + G + L+ D G ++C A +AG SAKL+V Sbjct: 738 TANGGRD--LVFSPVDRRDQGMYSCVALGSAGIGRAPSAKLIV 778 Score = 72.9 bits (171), Expect = 6e-12 Identities = 80/305 (26%), Positives = 117/305 (38%), Gaps = 33/305 (10%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKP--IDVYWLKNGKKVQPDIRNKILEEDGTYT 4570 PP +L Q++ + G L L V ++P + W K+G P + G Sbjct: 592 PPEVSL--QSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRD 649 Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 LL Y D G Y C A NS G +SL + P P + PL+ Sbjct: 650 LLFAPVYRTDQGSYTCEASNSVGNG-------ISLASRMTIHYP-------PVTSVSPLE 695 Query: 4631 DKIVAEGQAIEFSCKIV--GKPLPT-VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687 K EG C ++ G+P T W K + P+ +S L S Sbjct: 696 AK---EGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVSTANGGRDLVFSPVDR 752 Query: 4688 EDEGDYKCVAYNSAGRVTV-AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746 D+G Y CVA SAG +AKL V +TPL V EG + S Sbjct: 753 RDQGMYSCVALGSAGIGRAPSAKLIVNFEPSV----TVTPL---TVTEGSNVTLVCRTVS 805 Query: 4747 KIK-PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805 + + WL++G++ + Q+ E N +L D G +TC A A G ++ Sbjct: 806 QPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSST 865 Query: 4806 AKLVV 4810 A L++ Sbjct: 866 AALII 870 Score = 70.1 bits (164), Expect = 4e-11 Identities = 79/340 (23%), Positives = 129/340 (37%), Gaps = 34/340 (10%) Query: 4480 VFAAVAENRGGTAKCSA-NLVVEEKRRQGRGGI-VPPSFTLTAQNVNVTSGQLVRLDTKV 4537 +FA V G+ C A N V R I PP +++ ++ V Sbjct: 651 LFAPVYRTDQGSYTCEASNSVGNGISLASRMTIHYPPVTSVSPLEAKEGDNATLKCSVLV 710 Query: 4538 TGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596 +G P + W+K + P R + +G L+ +D G Y CVA+ SAG R Sbjct: 711 SGRPPATSFTWIKESQSFDPATRPSVSTANGGRDLVFSPVDRRDQGMYSCVALGSAGIGR 770 Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIVGKP-LPTV 4654 P+ K N P + + PL V EG + C+ V +P + Sbjct: 771 A--------PSAK-------LIVNFEPSVTVTPLT---VTEGSNVTLVCRTVSQPEIDRY 812 Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714 W K + S Q+++ + L D+G+Y C+A+N+ G + A L + Sbjct: 813 NWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSSTAALIINY 872 Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI---QWLREGALIPETPDFQMIH 4771 P + EG + + S +P++ WL++GA I ++ Sbjct: 873 R------PTVMVTAQASANEGDGLTLRCTVESS-QPSVGSYTWLKDGAEINLATHPRVRA 925 Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVV 4810 E L+ D G +TC AT + G A+L+V Sbjct: 926 ERGGRDLVFAPVGRADQGNYTCEATNSVGSGTSPPAQLIV 965 Score = 48.4 bits (110), Expect = 1e-04 Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 9/180 (5%) Query: 402 DVTEGKMTRFDCRV--TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 + EG C V +GRP +I + Q D + +G L+ + V D Sbjct: 695 EAKEGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVSTANGGRDLVFSPVDRRD 754 Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP- 518 G+ +CVA +G ++ E V + L V EG V L R V P Sbjct: 755 QGMYSCVALGSAGIGRAPSAKLIVNFEPSVT------VTPLTVTEGSNVTLVCRTVSQPE 808 Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 R W KDG + ++ + L + SD Y C A N G ++ A L Sbjct: 809 IDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSSTAAL 868 Score = 48.0 bits (109), Expect = 2e-04 Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 11/180 (6%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 VTEG CR +P + ++ D I + + E L V SD G Sbjct: 791 VTEGSNVTLVCRTVSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGN 850 Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522 TC+A N G + L + + V+ + + EG+ + L V + P + Sbjct: 851 YTCIAHNAIGGGSSTAALIINYRPTVMVT------AQASANEGDGLTLRC-TVESSQPSV 903 Query: 523 ---TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS-TATRARL 578 TW KDG I R+ + G L +D Y C A N GS T+ A+L Sbjct: 904 GSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGNYTCEATNSVGSGTSPPAQL 963 Score = 46.4 bits (105), Expect = 6e-04 Identities = 43/192 (22%), Positives = 70/192 (36%), Gaps = 9/192 (4%) Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106 PP+ T F ++ ++G A +++ + W +G +++ R G Sbjct: 497 PPD--TTFSPVM-ANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGR 553 Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166 L + TD G YSC A N G I + + P + +Q+I +G Sbjct: 554 YLVFSSLRRTDQGMYSCVALNSMG---IGRSIAAAKMTVNYPPEVS--LQSIVA-SEGGL 607 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226 A C+V+ P + W +G +T G L A D G Y C A Sbjct: 608 ATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSYTCEA 667 Query: 3227 YNKYGEDFTRAT 3238 N G + A+ Sbjct: 668 SNSVGNGISLAS 679 Score = 46.0 bits (104), Expect = 8e-04 Identities = 45/202 (22%), Positives = 77/202 (38%), Gaps = 15/202 (7%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEP-LPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 PP+ + + ++ + V G P W +E+ + + T + L Sbjct: 686 PPVTSVSPLEAKEGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVSTANGGRDL 745 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 + V D +++ VA G + SA L+V + PS T+T + VT Sbjct: 746 VFSPVDRRDQGMYSCVALGSAGIGRAPSAKLIVNFE----------PSVTVTP--LTVTE 793 Query: 4528 GQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586 G V L + ID Y WLK+G +++ +E L + D G Y C Sbjct: 794 GSNVTLVCRTVSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTC 853 Query: 4587 VAINSAGEARCDAECVVSLPAT 4608 +A N+ G A +++ T Sbjct: 854 IAHNAIGGGSSTAALIINYRPT 875 Score = 45.2 bits (102), Expect = 0.001 Identities = 44/172 (25%), Positives = 69/172 (40%), Gaps = 12/172 (6%) Query: 405 EGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV 463 +G C V +GRP ++ D D + +G L+ +++ +D G+ Sbjct: 509 QGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMY 568 Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI- 522 +CVA N G R K V P V ++ EG L + + P + Sbjct: 569 SCVALNSMGIG----RSIAAAKMTVNYPPEVS-LQSIVASEGGLATLRCSVIRSQPPVLS 623 Query: 523 -TWQKDGVPIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 TW+KDG+ P +P + + T GG L P +D Y C A N G+ Sbjct: 624 YTWRKDGLTFNPATHPNVSV-THGGRDLLFAP-VYRTDQGSYTCEASNSVGN 673 Score = 40.3 bits (90), Expect = 0.037 Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 4/73 (5%) Query: 942 RVEWLKDGR--PVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999 R WLKDG A S++T N +A V D G+YTC A+NAIG +++A L Sbjct: 811 RYNWLKDGSIFNTSAGSQVTQERNGKLLAFI--GVQRSDQGNYTCIAHNAIGGGSSTAAL 868 Query: 1000 TIVTKKDIIAESQ 1012 I + ++ +Q Sbjct: 869 IINYRPTVMVTAQ 881 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/83 (28%), Positives = 33/83 (39%) Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839 L +IV EG C+V S+ P L W + T + L Y Sbjct: 597 LQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVY 656 Query: 2840 EEDSGIYTCKATNSKGSATTSGS 2862 D G YTC+A+NS G+ + S Sbjct: 657 RTDQGSYTCEASNSVGNGISLAS 679 Score = 39.1 bits (87), Expect = 0.086 Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 3/111 (2%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P T TP L ++E S+ CR + + R W +G T + + + +L Sbjct: 782 PSVTVTP--LTVTEGSNVTLVCRTVSQPEID-RYNWLKDGSIFNTSAGSQVTQERNGKLL 838 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSG 3668 GV + D G YTC A N G + + L + R +++ Q ++ G Sbjct: 839 AFIGVQRSDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQASANEGDG 889 Score = 39.1 bits (87), Expect = 0.086 Identities = 22/73 (30%), Positives = 30/73 (41%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EGD + C VE S+ W + + T + + L D G Y Sbjct: 886 EGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGNY 945 Query: 2847 TCKATNSKGSATT 2859 TC+ATNS GS T+ Sbjct: 946 TCEATNSVGSGTS 958 Score = 38.7 bits (86), Expect = 0.11 Identities = 23/79 (29%), Positives = 34/79 (43%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 +G L V P W K+G+ + R + G L +SLR D G+Y Sbjct: 509 QGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMY 568 Query: 2716 TCKATNLLGEAVSTASIKI 2734 +C A N +G S A+ K+ Sbjct: 569 SCVALNSMGIGRSIAAAKM 587 Score = 38.7 bits (86), Expect = 0.11 Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 1/95 (1%) Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912 P ++EG + CR P+ + R W +G + + + + + L + V Sbjct: 788 PLTVTEGSNVTLVCRTVSQPEID-RYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRS 846 Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947 D G YTC A N +G S+ L + + +++ +Q Sbjct: 847 DQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881 Score = 38.7 bits (86), Expect = 0.11 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 5/96 (5%) Query: 1320 IETVEGTNVHLECRL--QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYP 1377 + EG+NV L CR QP D R W +G T + E + L + V Sbjct: 789 LTVTEGSNVTLVCRTVSQPEID---RYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQR 845 Query: 1378 EDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQ 1413 D G YTC A N +G ++ AL + + +++ +Q Sbjct: 846 SDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881 Score = 38.7 bits (86), Expect = 0.11 Identities = 35/152 (23%), Positives = 58/152 (38%), Gaps = 13/152 (8%) Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503 W ++ S Q+ +L V D + +A N G +A L++ + Sbjct: 814 WLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSSTAALIINYR 873 Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP-IDVY-WLKNGKKVQPDIRNK 4561 P+ +TAQ + G + L V ++P + Y WLK+G ++ + Sbjct: 874 ----------PTVMVTAQ-ASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPR 922 Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593 + E G L+ D G Y C A NS G Sbjct: 923 VRAERGGRDLVFAPVGRADQGNYTCEATNSVG 954 Score = 38.3 bits (85), Expect = 0.15 Identities = 23/76 (30%), Positives = 31/76 (40%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 EG L V P L W K+G+T + G L + D G Y Sbjct: 604 EGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSY 663 Query: 2716 TCKATNLLGEAVSTAS 2731 TC+A+N +G +S AS Sbjct: 664 TCEASNSVGNGISLAS 679 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/74 (29%), Positives = 29/74 (39%) Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGE 1916 SEG A C + P + W +G S G L VY D G Sbjct: 603 SEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGS 662 Query: 1917 YTCKAINNLGQAVS 1930 YTC+A N++G +S Sbjct: 663 YTCEASNSVGNGIS 676 Score = 37.9 bits (84), Expect = 0.20 Identities = 36/164 (21%), Positives = 60/164 (36%), Gaps = 7/164 (4%) Query: 3771 RATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPP 3830 + + + AT + T + RD+V + L I AP + IV+ P Sbjct: 723 KESQSFDPATRPSVSTANGGRDLVFSPVDRRDQGMYSCVALGSAGIGRAPSAKLIVNFEP 782 Query: 3831 KFITQIKSHTVEESEGVRFECRV--EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 + TV E V CR +P+ D R W ++G + + + + Sbjct: 783 S--VTVTPLTVTEGSNVTLVCRTVSQPEID---RYNWLKDGSIFNTSAGSQVTQERNGKL 837 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932 L + V D G Y C A N G + A + P +++ Q Sbjct: 838 LAFIGVQRSDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881 Score = 37.9 bits (84), Expect = 0.20 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713 + EG +V L + + + + + W K+G T A + T + L+ ++ D G Sbjct: 791 VTEGSNVTLVCRTVSQPEID-RYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQG 849 Query: 2714 IYTCKATNLLGEAVSTASIKIEDR 2737 YTC A N +G STA++ I R Sbjct: 850 NYTCIAHNAIGGGSSTAALIINYR 873 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/85 (29%), Positives = 33/85 (38%) Query: 918 QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977 Q S EG +E S WLKDG + ++ G L V Sbjct: 881 QASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRA 940 Query: 978 DAGHYTCRAYNAIGQATTSANLTIV 1002 D G+YTC A N++G T+ IV Sbjct: 941 DQGNYTCEATNSVGSGTSPPAQLIV 965 Score = 37.1 bits (82), Expect = 0.35 Identities = 42/147 (28%), Positives = 61/147 (41%), Gaps = 13/147 (8%) Query: 3778 SATTTAKITCSAKRDIVLES--QLPQGM-SGEKIKELERGRISDAPKEEPIVSTPPKFIT 3834 SAT + T + R +V S + QGM S + + GR A K V+ PP+ Sbjct: 540 SATRPSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMGIGRSIAAAKMT--VNYPPE--V 595 Query: 3835 QIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSGHRYRTVYDMGFVSLDILY 3893 ++S E C V + P L W ++G P+ H +V G D+L+ Sbjct: 596 SLQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGG---RDLLF 652 Query: 3894 --VYAEDSGEYICRAVNDFGEDFTKAT 3918 VY D G Y C A N G + A+ Sbjct: 653 APVYRTDQGSYTCEASNSVGNGISLAS 679 Score = 36.7 bits (81), Expect = 0.46 Identities = 39/171 (22%), Positives = 61/171 (35%), Gaps = 12/171 (7%) Query: 403 VTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461 + E T F C VTG+ +W + N + ++G L+ V +D G Sbjct: 416 LNESTSTTFTCTVTGQSGAFSYSWARDGSPFSLPANIHL---QNGGRDLVFAPVKRTDQG 472 Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG--TPT 519 TC A +++ T +++ + P FS + +G L V P Sbjct: 473 FYTCTA-SQNAVTKISPGVSLT----INFPPDTT-FSPVMANQGNSATLRCTVVSGRPPA 526 Query: 520 PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 TW KDG+ + T G L + +D Y C A N G Sbjct: 527 SSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMG 577 Score = 36.7 bits (81), Expect = 0.46 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 7/102 (6%) Query: 641 VPLKSVTAMEGGKIHFETRIEPVGDPTM-KIEWLKNGQ--SIEASSRFTSIFRFGYISLD 697 V + +T EG + R V P + + WLK+G + A S+ T R G + L Sbjct: 784 VTVTPLTVTEGSNVTLVCRT--VSQPEIDRYNWLKDGSIFNTSAGSQVTQE-RNGKL-LA 839 Query: 698 MLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQ 739 + + D G YTC A +A G + A L + R T+ T+Q Sbjct: 840 FIGVQRSDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881 Score = 36.7 bits (81), Expect = 0.46 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 3/95 (3%) Query: 3705 IDVPEGGPVHFDCRVEPVGDPTM-RIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763 + V EG V CR V P + R +W +G F T + + L + Sbjct: 789 LTVTEGSNVTLVCRT--VSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRS 846 Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798 D G YTC A N G ++TA + + + +++ +Q Sbjct: 847 DQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881 Score = 36.7 bits (81), Expect = 0.46 Identities = 32/148 (21%), Positives = 49/148 (33%), Gaps = 7/148 (4%) Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143 W +G S + +L +G + +D G Y+C A N G + L Sbjct: 814 WLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSSTAALII--- 870 Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203 +P T + +G CTV W +G + +T + ++ Sbjct: 871 --NYRP--TVMVTAQASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAE 926 Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 G L A D G Y C A N G Sbjct: 927 RGGRDLVFAPVGRADQGNYTCEATNSVG 954 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 2/86 (2%) Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912 P ++G SA C + P W +G S R S G L ++ Sbjct: 504 PVMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRT 563 Query: 1913 DSGEYTCKAINN--LGQAVSSIRLNV 1936 D G Y+C A+N+ +G+++++ ++ V Sbjct: 564 DQGMYSCVALNSMGIGRSIAAAKMTV 589 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 3/85 (3%) Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693 YPP V L+S+ A EGG + P + W K+G + ++ G Sbjct: 591 YPPE---VSLQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGG 647 Query: 694 ISLDMLSLNIQDSGEYTCRAVSATG 718 L + D G YTC A ++ G Sbjct: 648 RDLLFAPVYRTDQGSYTCEASNSVG 672 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 3/90 (3%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753 PP +++ +I EGG C V P + W +G F + + G Sbjct: 592 PPEVSLQ---SIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGR 648 Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTA 3783 L +Y D G YTC A+N G+ + A Sbjct: 649 DLLFAPVYRTDQGSYTCEASNSVGNGISLA 678 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPS-RDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 ++ ++ + KEGDN +C+V S R P W ++ TR + L Sbjct: 688 VTSVSPLEAKEGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVSTANGGRDLVF 747 Query: 2836 THTYEEDSGIYTCKATNSKG 2855 + D G+Y+C A S G Sbjct: 748 SPVDRRDQGMYSCVALGSAG 767 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/81 (25%), Positives = 31/81 (38%) Query: 2115 LTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYT 2174 +T+ + EGD C VE + W +G +I R + G L Sbjct: 878 VTAQASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPV 937 Query: 2175 YAEDSGTYMCKATNKLGEAVN 2195 D G Y C+ATN +G + Sbjct: 938 GRADQGNYTCEATNSVGSGTS 958 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 2/105 (1%) Query: 625 IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684 I PG + PP V A +G + P W+K+G ++++R Sbjct: 486 ISPGVSLTINFPPD--TTFSPVMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATR 543 Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729 + G L SL D G Y+C A+++ G+ + A +T Sbjct: 544 PSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMGIGRSIAAAKMT 588 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/76 (26%), Positives = 29/76 (38%) Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493 EG A + + P L W +G + + G L +P Y D G Y Sbjct: 604 EGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSY 663 Query: 3494 LCRAYNNYGEAVTTAS 3509 C A N+ G ++ AS Sbjct: 664 TCEASNSVGNGISLAS 679 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 3/96 (3%) Query: 1186 PPPVSEGKNIHLECRLEPMGDPTM-RVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244 P V+EG N+ L CR + P + R W +G + + + L I Sbjct: 788 PLTVTEGSNVTLVCRT--VSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQR 845 Query: 1245 ADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280 +D G YT A N +G ++A + + R ++ Q Sbjct: 846 SDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 5/75 (6%) Query: 797 VSDPTM-RVEWYKDGRPI--TASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853 VS P + R W KDG +A S++T N G + L + ++ D G+YT A N +G Sbjct: 804 VSQPEIDRYNWLKDGSIFNTSAGSQVTQERN-GKL-LAFIGVQRSDQGNYTCIAHNAIGG 861 Query: 854 AISTASIRVAARSTV 868 STA++ + R TV Sbjct: 862 GSSTAALIINYRPTV 876 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/76 (28%), Positives = 28/76 (36%) Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843 EG A + P + W KDG ++ G L + D GSY Sbjct: 604 EGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSY 663 Query: 844 TVRAVNKLGEAISTAS 859 T A N +G IS AS Sbjct: 664 TCEASNSVGNGISLAS 679 Score = 33.9 bits (74), Expect = 3.2 Identities = 16/69 (23%), Positives = 32/69 (46%) Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449 +G +A C ++ P W ++ + ++R + + G + S +R D+G+Y Sbjct: 509 QGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMY 568 Query: 2450 MCRASNLLG 2458 C A N +G Sbjct: 569 SCVALNSMG 577 Score = 33.9 bits (74), Expect = 3.2 Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 2/105 (1%) Query: 52 VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111 + S G + I A + PP E ++ ++GG A + + PV+S+T +K Sbjct: 573 LNSMGIGRSIAAAKMTVNYPP--EVSLQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDG 630 Query: 112 LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 L + G LL + D+G YTC A N G I Sbjct: 631 LTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSYTCEASNSVGNGI 675 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/80 (27%), Positives = 29/80 (36%) Query: 919 ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978 I EGG A + L W KDG ++ G L V D Sbjct: 600 IVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTD 659 Query: 979 AGHYTCRAYNAIGQATTSAN 998 G YTC A N++G + A+ Sbjct: 660 QGSYTCEASNSVGNGISLAS 679 Score = 33.9 bits (74), Expect = 3.2 Identities = 19/68 (27%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 279 EGADAQFQVQLSGNPR-PRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337 EG++ + P R W K+G S ++ N L Q+SD G+YT Sbjct: 793 EGSNVTLVCRTVSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYT 852 Query: 338 LLAENPNG 345 +A N G Sbjct: 853 CIAHNAIG 860 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 4/81 (4%) Query: 945 WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNA--IGQATTSANLTIV 1002 W+KDG ++++R + G L S+ D G Y+C A N+ IG++ +A +T+ Sbjct: 531 WMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMGIGRSIAAAKMTVN 590 Query: 1003 TKKDIIAES--QHPGGLEKIQ 1021 ++ +S GGL ++ Sbjct: 591 YPPEVSLQSIVASEGGLATLR 611 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 2/83 (2%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 PP+ T +P ++ ++ +SA C ++ + W +G + +R G Sbjct: 497 PPDTTFSP--VMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRY 554 Query: 3617 LEIGGVYQRDAGLYTCKATNRHG 3639 L + + D G+Y+C A N G Sbjct: 555 LVFSSLRRTDQGMYSCVALNSMG 577 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/84 (22%), Positives = 32/84 (38%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 ++ +G++ C V R P W + S TR + L + D Sbjct: 505 VMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTD 564 Query: 2843 SGIYTCKATNSKGSATTSGSLRCT 2866 G+Y+C A NS G + + + T Sbjct: 565 QGMYSCVALNSMGIGRSIAAAKMT 588 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 2/83 (2%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 PPE + ++ SE A C +I + W +G + G Sbjct: 592 PPEVSL--QSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRD 649 Query: 3617 LEIGGVYQRDAGLYTCKATNRHG 3639 L VY+ D G YTC+A+N G Sbjct: 650 LLFAPVYRTDQGSYTCEASNSVG 672 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/85 (23%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 1984 IKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYA- 2042 +++ +EG L ++ P + W +G + G D+L+A Sbjct: 597 LQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHG--GRDLLFAP 654 Query: 2043 -YAEDTGTYMCKATNAVGEAVTTSS 2066 Y D G+Y C+A+N+VG ++ +S Sbjct: 655 VYRTDQGSYTCEASNSVGNGISLAS 679 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/73 (26%), Positives = 28/73 (38%) Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182 EG A C V P L+ W +G + G L Y D G+Y Sbjct: 604 EGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSY 663 Query: 2183 MCKATNKLGEAVN 2195 C+A+N +G ++ Sbjct: 664 TCEASNSVGNGIS 676 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/86 (26%), Positives = 30/86 (34%) Query: 3696 RFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIAL 3755 R TV + EG + C VE W +G + + G L Sbjct: 873 RPTVMVTAQASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDL 932 Query: 3756 DIDYIYARDAGEYTCRATNKWGSATT 3781 + D G YTC ATN GS T+ Sbjct: 933 VFAPVGRADQGNYTCEATNSVGSGTS 958 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/73 (27%), Positives = 28/73 (38%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 EG + L VE W K+G + + + G L + D G Y Sbjct: 886 EGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGNY 945 Query: 2716 TCKATNLLGEAVS 2728 TC+ATN +G S Sbjct: 946 TCEATNSVGSGTS 958 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/102 (22%), Positives = 41/102 (40%), Gaps = 2/102 (1%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PP P + A + V P TW K+G ++ + + TT+ L Sbjct: 497 PPDTTFSPVMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLV 556 Query: 325 VRNTQKSDSGHYTLLAENPNGC--IVTSGYLAVESPTESYVQ 364 + +++D G Y+ +A N G + + + V P E +Q Sbjct: 557 FSSLRRTDQGMYSCVALNSMGIGRSIAAAKMTVNYPPEVSLQ 598 Score = 32.3 bits (70), Expect = 9.9 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 6/94 (6%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 +TV P+ S L +I EG L C + + W +G P Sbjct: 587 MTVNYPPEVS--LQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATH--PNVS 642 Query: 1365 FDYVALDLL--SVYPEDSGVYTCQATNQLGEAVT 1396 + DLL VY D G YTC+A+N +G ++ Sbjct: 643 VTHGGRDLLFAPVYRTDQGSYTCEASNSVGNGIS 676 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/78 (24%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 1737 VGDPKL-RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795 V P++ R WL++G S + L V D G YTC A N +G Sbjct: 804 VSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGS 863 Query: 1796 TSSTLFVQSKASLQLESQ 1813 +++ L + + ++ + +Q Sbjct: 864 STAALIINYRPTVMVTAQ 881 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/71 (25%), Positives = 28/71 (39%) Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGE 1249 +EG + L C +E W +G + + + + + G L AD G Sbjct: 885 NEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGN 944 Query: 1250 YTVRAVNHLGS 1260 YT A N +GS Sbjct: 945 YTCEATNSVGS 955 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/70 (28%), Positives = 28/70 (40%) Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517 EG + C +E S W K+G + + R + G L + D G Y Sbjct: 886 EGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGNY 945 Query: 1518 TCRAVNLVGT 1527 TC A N VG+ Sbjct: 946 TCEATNSVGS 955 >SB_41825| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 825 Score = 77.8 bits (183), Expect = 2e-13 Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 13/204 (6%) Query: 376 QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR-D 434 Q + R+E+ E P + D V G + + C TG P P ++W + D + + Sbjct: 389 QFSKKARLEVLE---FPVLTRKPHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFP 445 Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494 K + + H +I N D+G TC A N +G + V+E P+F+ Sbjct: 446 AAEEKRIEHLPSEHLFIIRNARGVDTGAYTCTATNGAGSINATAYVTVLE-----VPRFM 500 Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554 + + VR GE VL +A G+P PR TW KD + + + H L Sbjct: 501 QSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVTLSARVVAH----GQLLVFVTVL 556 Query: 555 ASDAAWYQCTAQNVAGSTATRARL 578 D Y C N G+ RL Sbjct: 557 PGDEGTYTCQVSNSLGTARQNTRL 580 Score = 64.9 bits (151), Expect = 2e-09 Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 22/203 (10%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKVQPDIRNKILEE-DGTYTL 4571 P T +V+V G L++L TG + W + +GK P K +E + Sbjct: 402 PVLTRKPHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLF 461 Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631 +I A D+G Y C A N AG A V P ++ + Sbjct: 462 IIRNARGVDTGAYTCTATNGAGSINATAYVTVL----------------EVPRFMQSMVS 505 Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691 K V G++ CK G P+P WYK DK + S A L P DEG Sbjct: 506 KRVRTGESAVLECKASGSPMPRFTWYKDDKKVTLSARV----VAHGQLLVFVTVLPGDEG 561 Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQ 4714 Y C NS G +L V + Sbjct: 562 TYTCQVSNSLGTARQNTRLTVVE 584 Score = 55.2 bits (127), Expect = 1e-06 Identities = 53/242 (21%), Positives = 96/242 (39%), Gaps = 26/242 (10%) Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 L ++ D+G Y+C+A N G ++ K + + P +P Sbjct: 365 LFLISVDFSDAGLYQCIASNKYG--------------SQFSKKARLEVLEFPVLTRKP-H 409 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK--PSKYFQMSRTADEYTLRISEAFPE 4688 D V G I+ C G P+P + W GD K ++ ++ E+ I A Sbjct: 410 DVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNARGV 469 Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748 D G Y C A N AG + A + V + + + ++ R V G+ A + + + Sbjct: 470 DTGAYTCTATNGAGSINATAYVTVLEVPRF--MQSMVSKR---VRTGESAVLECKASGSP 524 Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 P W ++ + T +++ G +L+ D GT+TC+ + + G + +L Sbjct: 525 MPRFTWYKDDKKV--TLSARVVAHGQ--LLVFVTVLPGDEGTYTCQVSNSLGTARQNTRL 580 Query: 4809 VV 4810 V Sbjct: 581 TV 582 Score = 53.6 bits (123), Expect = 4e-06 Identities = 42/128 (32%), Positives = 58/128 (45%), Gaps = 8/128 (6%) Query: 447 NHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505 N L + +V SD+G+ C+A NK G + + + RL V+E P + ++V G Sbjct: 362 NSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLE-----FPVLTRKPHDVSVHVG 416 Query: 506 EPVVLNARAVGTPTPRITWQK-DGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQC 563 + L A G P P I+W+ DG P E RI I A+ D Y C Sbjct: 417 GLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNARGVDTGAYTC 476 Query: 564 TAQNVAGS 571 TA N AGS Sbjct: 477 TATNGAGS 484 Score = 50.0 bits (114), Expect = 5e-05 Identities = 48/197 (24%), Positives = 77/197 (39%), Gaps = 20/197 (10%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY----RENFPIKNSPDFQIHTFSTKS 4466 P+ T+K V + G P+P+I W + FP + + +I ++ Sbjct: 402 PVLTRKPHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPA--AEEKRIEHLPSEH 459 Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526 + IIR D+ + A N G+ +A + V E P F + + V Sbjct: 460 LFIIRNARGVDTGAYTCTATNGAGSINATAYVTVLEV----------PRFMQSMVSKRVR 509 Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586 +G+ L+ K +G+ W K+ KKV R + G L+ + P D G Y C Sbjct: 510 TGESAVLECKASGSPMPRFTWYKDDKKVTLSAR---VVAHGQL-LVFVTVLPGDEGTYTC 565 Query: 4587 VAINSAGEARCDAECVV 4603 NS G AR + V Sbjct: 566 QVSNSLGTARQNTRLTV 582 Score = 49.6 bits (113), Expect = 6e-05 Identities = 54/207 (26%), Positives = 91/207 (43%), Gaps = 22/207 (10%) Query: 4619 ANAPPEI-IEPLKDKIVAEGQAIEFSCKI--VGKPLPTV--QWYKGDKLIKPSKYFQMSR 4673 +N P+I + P K + G + C++ V + +V QW G ++I R Sbjct: 294 SNPIPQISVHPPSQKAM-RGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITDFVR 352 Query: 4674 TADEYTLRI-SEAFP-----EDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTP 4726 T D+ + S+ F D G Y+C+A N G + + A+L+V + P LT Sbjct: 353 TDDDDIVTYNSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLE------FPVLTR 406 Query: 4727 L-RDIVVYEGQPAQFKTQITSKIKPTIQW-LREG-ALIPETPDFQMIHEGNNAVLLIGNT 4783 D+ V+ G + T P I W + +G + P + ++ H + + +I N Sbjct: 407 KPHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNA 466 Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVV 4810 DTG +TC AT AG + +A + V Sbjct: 467 RGVDTGAYTCTATNGAGSINATAYVTV 493 Score = 46.8 bits (106), Expect = 4e-04 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 6/99 (6%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 +TV++ P+F +++ + G + LEC+ G R W+ + K + R + Sbjct: 491 VTVLEVPRFMQSMVSKRVRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVVAHGQ 548 Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 L ++V P D G YTCQ +N LG A + L V+ Sbjct: 549 L----LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTVV 583 Score = 45.6 bits (103), Expect = 0.001 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 5/93 (5%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P+F++ + V G+ +C+ +G P P TW+ +D+++ + +++ + L+ Sbjct: 497 PRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVT--LSARVVAH---GQLLV 551 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484 V D G TC N G RL V+E Sbjct: 552 FVTVLPGDEGTYTCQVSNSLGTARQNTRLTVVE 584 Score = 44.8 bits (101), Expect = 0.002 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 7/99 (7%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897 V V + PRF+ + ++ G+SA EC+ P P R WY + K + R Sbjct: 491 VTVLEVPRFMQSMVSK-RVRTGESAVLECKASGSPMP--RFTWYKDDKKVTLSARVVAHG 547 Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 L +TV D G YTC+ N+LG A + RL V Sbjct: 548 QL----LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTV 582 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 7/95 (7%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F+Q + + V G++ LEC+ G P R W+ + + VT+ +R + Sbjct: 497 PRFMQSMVSKR-VRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVVAHGQL---- 549 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271 L + D G YT + N LG+A + + V+E Sbjct: 550 LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTVVE 584 Score = 38.3 bits (85), Expect = 0.15 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 6/96 (6%) Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 + + P F M RV ++A E + G P R W ++ + S R+ Sbjct: 493 VLEVPRFMQSMVSKRVRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVVAHGQL- 549 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 L V P D GTYTC+ N LG A ++ L V Sbjct: 550 ---LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTV 582 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 6/84 (7%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P F Q + R G +A E K G+P P +W + + K ++ L Sbjct: 497 PRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYK------DDKKVTLSARVVAHGQLL 550 Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155 + + PGDEG YTC N G A Sbjct: 551 VFVTVLPGDEGTYTCQVSNSLGTA 574 Score = 38.3 bits (85), Expect = 0.15 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+ Q + +++ G A + + SG+P PR TW+K+ +++ S + + H + V Sbjct: 497 PRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVTLSAR---VVAHGQLLVFV 553 Query: 326 RNTQKSDSGHYTLLAENPNG 345 D G YT N G Sbjct: 554 -TVLPGDEGTYTCQVSNSLG 572 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 7/83 (8%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P F Q + + ++ G++A +C+ G P + W++++K + S+R+ H V Sbjct: 497 PRFMQSMVS-KRVRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVV-AHGQLLVF 552 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 +T V DEG Y C+ SN LG Sbjct: 553 VT---VLPGDEGTYTCQVSNSLG 572 Score = 37.9 bits (84), Expect = 0.20 Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 16/169 (9%) Query: 3075 TGDQSMVIEW-FYNGKT-IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132 TG VI W +GK+ A+ R + + I + D+G Y+C ATN G Sbjct: 426 TGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNARGVDTGAYTCTATNGAGSI 485 Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192 + + + + PRF + + + ++ G+SA EC P + WY + + + Sbjct: 486 NATAYVTVL-----EVPRFMQSMVS-KRVRTGESAVLECKA--SGSPMPRFTWYKDDKKV 537 Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATI 3239 S R+ G +++ + D G Y C+ N G TR T+ Sbjct: 538 TLSARVVA---HGQLLVFVTVLPG-DEGTYTCQVSNSLGTARQNTRLTV 582 Score = 37.5 bits (83), Expect = 0.26 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 7/102 (6%) Query: 2903 VPDTEYPKPEWII-PIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQG--SR 2959 V DT P P+ + P + + + L QV +N ++++W +V+ + + Sbjct: 290 VCDTSNPIPQISVHPPSQKAMRGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITD 349 Query: 2960 FKLTSDFGFVT----LDLVDVYERDSGIYTCKAYNKRGEAFT 2997 F T D VT L L+ V D+G+Y C A NK G F+ Sbjct: 350 FVRTDDDDIVTYNSDLFLISVDFSDAGLYQCIASNKYGSQFS 391 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 4/92 (4%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P F + M RV E A E + G P+P WY+++ + S H +L+ Sbjct: 497 PRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVTLSARVVAH----GQLLVF 552 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502 V D + N GTA+ + L V E Sbjct: 553 VTVLPGDEGTYTCQVSNSLGTARQNTRLTVVE 584 Score = 37.5 bits (83), Expect = 0.26 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 4/66 (6%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G R W KD + V S+R+ L +V D G YTC+ N++G A + Sbjct: 522 GSPMPRFTWYKDDKKVTLSARVVAHGQL----LVFVTVLPGDEGTYTCQVSNSLGTARQN 577 Query: 997 ANLTIV 1002 LT+V Sbjct: 578 TRLTVV 583 Score = 37.1 bits (82), Expect = 0.35 Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 3/146 (2%) Query: 213 TDHSSTDDFKVDTFEYRL-LREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQK 271 TD TDD + T+ L L V F ++ + + + L + P + +K Sbjct: 348 TDFVRTDDDDIVTYNSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTRK 407 Query: 272 PRNSKLQEGADAQFQVQLSGNPRPRVTW-FKNGQ-RLINSNKHEIITTHNHTTLRVRNTQ 329 P + + G + +G P P ++W +G+ + + + I + +RN + Sbjct: 408 PHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNAR 467 Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAV 355 D+G YT A N G I + Y+ V Sbjct: 468 GVDTGAYTCTATNGAGSINATAYVTV 493 Score = 36.3 bits (80), Expect = 0.61 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 7/93 (7%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F+ ++ S + ++ G+ A EC+ P T W+ + +K+ R H V Sbjct: 497 PRFMQSMVS-KRVRTGESAVLECKASGSPMPRFT--WYKDDKKVTLSARV-VAHGQLLVF 552 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + +L D GTY C+ +N LG A L V Sbjct: 553 VTVL---PGDEGTYTCQVSNSLGTARQNTRLTV 582 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 7/93 (7%) Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829 P+F++ + ++ G +A E + + P R WYKD + +T S+R+ + G + Sbjct: 497 PRFMQSMVSK-RVRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVVA---HGQLL 550 Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 + + L D G+YT + N LG A + V Sbjct: 551 VFVTVLPG-DEGTYTCQVSNSLGTARQNTRLTV 582 Score = 35.5 bits (78), Expect = 1.1 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 8/80 (10%) Query: 86 GGNAKFEGKLRGNPTPVVSWT----RKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDE 141 GG K G P PV+SW + K P E R + +I+ D Sbjct: 416 GGLIKLPCAATGYPVPVISWRMGDGKSKFPAAE----EKRIEHLPSEHLFIIRNARGVDT 471 Query: 142 GEYTCTARNQYGEAICSVYI 161 G YTCTA N G + Y+ Sbjct: 472 GAYTCTATNGAGSINATAYV 491 Score = 35.5 bits (78), Expect = 1.1 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 7/92 (7%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 PRF+ S + V G+ ECK + W+K+ + VT+ R + G + Sbjct: 497 PRFMQSMVS-KRVRTGESAVLECKASG--SPMPRFTWYKDDKKVTLSAR---VVAHGQL- 549 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 L + ++ D G YTC+ N +GT + RLT Sbjct: 550 LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLT 581 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 7/99 (7%) Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096 V + + PRF+ + + ++ G+SA E + T WY + K++T + R+ + Sbjct: 491 VTVLEVPRFMQSMV-SKRVRTGESAVLECKASGSPMPRFT--WYKDDKKVTLSARVVAHG 547 Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135 L +V D G YT N+ G A+ + +TV Sbjct: 548 QL----LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTV 582 Score = 33.9 bits (74), Expect = 3.2 Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 1613 WYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 WY ++K + +R L ++ LP D GTYTC+ N+LG A Sbjct: 530 WYKDDKKVTLSARVVAHGQL----LVFVTVLPGDEGTYTCQVSNSLGTA 574 Score = 33.1 bits (72), Expect = 5.7 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 8/112 (7%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPV--GDQTMRVEWFCNGKPIKTGH--RFRPAYEFD 1366 PQ S + + + G NV L CR+Q V ++R++W + I F + D Sbjct: 298 PQISVHPPSQKAMRGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITDFVRTDDDD 357 Query: 1367 YVA----LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414 V L L+SV D+G+Y C A+N+ G + A + + ++ H Sbjct: 358 IVTYNSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTRKPH 409 Score = 32.3 bits (70), Expect = 9.9 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 10/88 (11%) Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDW-FHNGR---PFATGSRV-HTLNDFGFIALDID 3758 ++ V GG + C G P I W +G+ P A R+ H ++ FI + Sbjct: 410 DVSVHVGGLIKLPCAA--TGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNAR 467 Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKIT 3786 + D G YTC ATN GS TA +T Sbjct: 468 GV---DTGAYTCTATNGAGSINATAYVT 492 >SB_40708| Best HMM Match : SRCR (HMM E-Value=0) Length = 1976 Score = 77.0 bits (181), Expect = 4e-13 Identities = 80/321 (24%), Positives = 122/321 (38%), Gaps = 41/321 (12%) Query: 4440 PLIK-WYRENFPIKNSPDFQIH-TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497 P+I W ++ PI + + T T L++ V D + V +N G+ S Sbjct: 1672 PIISDWLKDGKPIDENDVKSLRITTDTSGQLVVNNVQRSDFGNYTCVLKNSAGSISASTI 1731 Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557 + V E R +V S +L A+ GQ + ++ ++ W +NG ++ Sbjct: 1732 VTVNEAPR-----VVDFSPSLLAK------GQTAYIYCNISSYPTANITWKRNGAVLKGP 1780 Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617 N +TL I A +DSG+YEC A N G A + V +P++ Sbjct: 1781 RYNVFTNN---FTLAIYNAVFEDSGQYECTAQNWLGTASANVSVSVGMPSS--------- 1828 Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677 A AP + +V Q + C G+P P V W K IK +R + Sbjct: 1829 IATAPSK-------TVVNPSQRVTLKCNATGQPQPVVTWKKDGVTIKTGP----NRVVEP 1877 Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737 TL I D G Y C+A N TV + + V+ P + P ++I V G Sbjct: 1878 GTLTIGVVSRADTGMYACIAQNPQNIATVFSSVIVSGPPIINR-----PPQNISVLTGAN 1932 Query: 4738 AQFKTQITSKIKPTIQWLREG 4758 F Q P W G Sbjct: 1933 VSFLCQAMGSPPPVFTWYHNG 1953 Score = 66.5 bits (155), Expect = 5e-10 Identities = 53/188 (28%), Positives = 90/188 (47%), Gaps = 12/188 (6%) Query: 389 ALAPQF-VKVCQDRDVTEGKMTRFDCR-VTGRPYPEVTWFINDRQIRDDYNHKIL-VNES 445 ++AP+F V+ + T R CR V P ++ ++ D + D+ + K L + Sbjct: 1638 SIAPEFQVQPANNITTTTESAFRIGCRSVPPVVTPIISDWLKDGKPIDENDVKSLRITTD 1697 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505 + L++ NV SD G TCV +N +G + + V E AP+ V+ FS + +G Sbjct: 1698 TSGQLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTVNE-----APRVVD-FSPSLLAKG 1751 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 + + PT ITW+++G ++ P + T+ TL I A D+ Y+CTA Sbjct: 1752 QTAYIYCNISSYPTANITWKRNGA-VLKGPRYNVFTNN--FTLAIYNAVFEDSGQYECTA 1808 Query: 566 QNVAGSTA 573 QN G+ + Sbjct: 1809 QNWLGTAS 1816 Score = 63.7 bits (148), Expect = 3e-09 Identities = 42/106 (39%), Positives = 59/106 (55%), Gaps = 9/106 (8%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT-S 1896 V VN+APR + P+ L++GQ+A+ C I YP N + W NG VL+ G RY + Sbjct: 1732 VTVNEAPRVVDF--SPSLLAKGQTAYIYCNISSYPTAN--ITWKRNGAVLK-GPRYNVFT 1786 Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942 N+F A I EDSG+Y C A N LG A +++ ++V SI Sbjct: 1787 NNFTLA---IYNAVFEDSGQYECTAQNWLGTASANVSVSVGMPSSI 1829 Score = 63.3 bits (147), Expect = 5e-09 Identities = 48/166 (28%), Positives = 68/166 (40%), Gaps = 15/166 (9%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 + +G+ C ++ P +TW N ++ + + N N L I N DSG Sbjct: 1748 LAKGQTAYIYCNISSYPTANITWKRNGAVLKGP-RYNVFTN---NFTLAIYNAVFEDSGQ 1803 Query: 463 VTCVARNKSGETAFQCRLNV-IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521 C A+N G + ++V + AP S V + V L A G P P Sbjct: 1804 YECTAQNWLGTASANVSVSVGMPSSIATAP------SKTVVNPSQRVTLKCNATGQPQPV 1857 Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 +TW+KDGV I P R+ G TL I +D Y C AQN Sbjct: 1858 VTWKKDGVTIKTGPN-RVVEPG---TLTIGVVSRADTGMYACIAQN 1899 Score = 57.6 bits (133), Expect = 2e-07 Identities = 63/224 (28%), Positives = 90/224 (40%), Gaps = 33/224 (14%) Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497 P I W R +K P + + T + ++ I VF EDS + A+N GTA SAN Sbjct: 1764 PTANITWKRNGAVLKG-PRYNVFT-NNFTLAIYNAVF-EDSGQYECTAQNWLGTA--SAN 1818 Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557 + V +P S V Q V L TG V W K+G ++ Sbjct: 1819 VSVSVG--------MPSSIATAPSKTVVNPSQRVTLKCNATGQPQPVVTWKKDGVTIKTG 1870 Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617 N+++E GT T+ ++ D+G Y C+A N A + +VS P Sbjct: 1871 -PNRVVEP-GTLTIGVVSR--ADTGMYACIAQNPQNIATVFSSVIVSGPPI--------- 1917 Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661 N PP+ I V G + F C+ +G P P WY K Sbjct: 1918 -INRPPQNIS------VLTGANVSFLCQAMGSPPPVFTWYHNGK 1954 Score = 56.0 bits (129), Expect = 7e-07 Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 14/197 (7%) Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV--QWYKGDKLIKPSKYFQMSRTA 4675 A+ AP ++P + A C+ V + + W K K I + + T Sbjct: 1637 ASIAPEFQVQPANNITTTTESAFRIGCRSVPPVVTPIISDWLKDGKPIDENDVKSLRITT 1696 Query: 4676 DEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADNLPALTPLRDIVVY 4733 D L ++ D G+Y CV NSAG ++ + + V + P D P+L + Sbjct: 1697 DTSGQLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTVNEAPRVVDFSPSL-------LA 1749 Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793 +GQ A I+S I W R GA++ + P + + NN L I N ED+G + C Sbjct: 1750 KGQTAYIYCNISSYPTANITWKRNGAVL-KGPRYNVFT--NNFTLAIYNAVFEDSGQYEC 1806 Query: 4794 RATTAAGQVETSAKLVV 4810 A G + + V Sbjct: 1807 TAQNWLGTASANVSVSV 1823 Score = 52.4 bits (120), Expect = 9e-06 Identities = 52/261 (19%), Positives = 97/261 (37%), Gaps = 18/261 (6%) Query: 100 TPVVS-WTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158 TP++S W + P+ E + S+R T L++ + D G YTC +N G S Sbjct: 1671 TPIISDWLKDGKPIDENDVKSLRITTDTSG-QLVVNNVQRSDFGNYTCVLKNSAGSISAS 1729 Query: 159 VYIQP-EGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSS 217 + E + +Y T T +++ K N Sbjct: 1730 TIVTVNEAPRVVDFSPSLLAKGQTAYIYCNISSYPTANITWKRNGAVLKGPRYN----VF 1785 Query: 218 TDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL 277 T++F + + + + E + ++G + +S + P IA P + + Sbjct: 1786 TNNFTLAIYN-AVFEDSGQYECTAQNWLGTASANVSVSVGM------PSSIATAPSKTVV 1838 Query: 278 QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337 + +G P+P VTW K+G I + + ++ TL + ++D+G Y Sbjct: 1839 NPSQRVTLKCNATGQPQPVVTWKKDGV-TIKTGPNRVV---EPGTLTIGVVSRADTGMYA 1894 Query: 338 LLAENPNGCIVTSGYLAVESP 358 +A+NP + V P Sbjct: 1895 CIAQNPQNIATVFSSVIVSGP 1915 Score = 46.8 bits (106), Expect = 4e-04 Identities = 54/227 (23%), Positives = 86/227 (37%), Gaps = 15/227 (6%) Query: 78 FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIG 137 F + A+G A + PT ++W R A L RYN T + +L I Sbjct: 1743 FSPSLLAKGQTAYIYCNISSYPTANITWKRNGAVLK-----GPRYNVFTNNFTLAIYNAV 1797 Query: 138 PGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYT 197 D G+Y CTA+N G A S + + S+ V K T Sbjct: 1798 FEDSGQYECTAQNWLGTA--SANVSVSVGMPSSIATAPSKTVVNPSQRVTLKCNATGQPQ 1855 Query: 198 TEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEID 257 + + V G + +V + VS ++ + ++ I+T + Sbjct: 1856 PVVTWKKDGVTIKTGPN-------RVVEPGTLTIGVVSRADTGMYACIAQNPQNIAT-VF 1907 Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304 S+ PP I + P+N + GA+ F Q G+P P TW+ NG+ Sbjct: 1908 SSVIVSGPPIINRPPQNISVLTGANVSFLCQAMGSPPPVFTWYHNGK 1954 Score = 44.8 bits (101), Expect = 0.002 Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 14/128 (10%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V + C TG+P P VTW + I+ N + E G L I V+ +D+G+ Sbjct: 1838 VNPSQRVTLKCNATGQPQPVVTWKKDGVTIKTGPNRVV---EPGT--LTIGVVSRADTGM 1892 Query: 463 VTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEPVVLNARAVGTPTP 520 C+A+N T F +VI V P + R ++V G V +A+G+P P Sbjct: 1893 YACIAQNPQNIATVFS---SVI----VSGPPIINRPPQNISVLTGANVSFLCQAMGSPPP 1945 Query: 521 RITWQKDG 528 TW +G Sbjct: 1946 VFTWYHNG 1953 Score = 44.8 bits (101), Expect = 0.002 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G+P P++ W ++ IK P+ + T +I ++ + D+ ++A +A+N A Sbjct: 1852 GQPQPVVTWKKDGVTIKTGPNRVVEP-GTLTIGVVSRA---DTGMYACIAQNPQNIATVF 1907 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555 ++++V PP QN++V +G V + G+ P W NGK+ Sbjct: 1908 SSVIVSG----------PPIINRPPQNISVLTGANVSFLCQAMGSPPPVFTWYHNGKEKN 1957 Query: 4556 PDI 4558 DI Sbjct: 1958 KDI 1960 Score = 41.1 bits (92), Expect = 0.021 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 5/105 (4%) Query: 275 SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334 S L +G A +S P +TW +NG ++ ++ + T N+ TL + N DSG Sbjct: 1746 SLLAKGQTAYIYCNISSYPTANITWKRNG-AVLKGPRYNVFT--NNFTLAIYNAVFEDSG 1802 Query: 335 HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRET 379 Y A+N G S ++V S + S+ + + QR T Sbjct: 1803 QYECTAQNWLG--TASANVSVSVGMPSSIATAPSKTVVNPSQRVT 1845 Score = 40.7 bits (91), Expect = 0.028 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 1185 NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244 +P +++G+ ++ C + PT + W NG +V G R+ + + F L I +A Sbjct: 1744 SPSLLAKGQTAYIYCNISSY--PTANITWKRNG-AVLKGPRYNVFTN-NFT-LAIYNAVF 1798 Query: 1245 ADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT 1277 D+G+Y A N LG+A + V V S I T Sbjct: 1799 EDSGQYECTAQNWLGTASANVSVSVGMPSSIAT 1831 Score = 40.3 bits (90), Expect = 0.037 Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 19/163 (11%) Query: 3073 IPTGDQSMVIEWFYNGKTIEA----SHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128 +P ++ +W +GK I+ S RI T + +VV + + +D G Y+C N Sbjct: 1666 VPPVVTPIISDWLKDGKPIDENDVKSLRITTDTSGQLVVNNV---QRSDFGNYTCVLKNS 1722 Query: 3129 WGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHN 3188 G S + + + PR ++ L GQ+A+ C + P I W N Sbjct: 1723 AGSISASTIV-----TVNEAPRVVDFSPSL--LAKGQTAYIYCNISSY--PTANITWKRN 1773 Query: 3189 GQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 G ++ ++F + + + DSG+Y C A N G Sbjct: 1774 GAVLKGPRYNVFTNNFTLAIYNAVF---EDSGQYECTAQNWLG 1813 Score = 39.9 bits (89), Expect = 0.049 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 7/80 (8%) Query: 3294 LVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF-HDFGIVILDILYCYEENS 3352 L +GQ+A+ + P + W NG L G RY F ++F + I + ++ E+S Sbjct: 1748 LAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYNVFTNNFTLAIYNAVF---EDS 1801 Query: 3353 GEYECVATNKLGRDSTKANL 3372 G+YEC A N LG S ++ Sbjct: 1802 GQYECTAQNWLGTASANVSV 1821 Score = 39.5 bits (88), Expect = 0.065 Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 7/140 (5%) Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567 +S+ G + LE K +EG+I + +GY G + A PEF P++ Sbjct: 1594 SSLCYNGVTCVDLELLTNKQIEGSIC-LQCPDGYMGDGELCRVIASIA--PEFQVQPANN 1650 Query: 3568 ILSENSSA-HFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKT--INDFGFVILEIGGVYQ 3624 I + SA CR +P + + +W +GKP + + VK+ I L + V + Sbjct: 1651 ITTTTESAFRIGCRSVPPVVTPIISDWLKDGKP-IDENDVKSLRITTDTSGQLVVNNVQR 1709 Query: 3625 RDAGLYTCKATNRHGEATVS 3644 D G YTC N G + S Sbjct: 1710 SDFGNYTCVLKNSAGSISAS 1729 Score = 39.5 bits (88), Expect = 0.065 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 7/97 (7%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEA----SSRITTFFNF 964 PEF+ + I+ R P + + +WLKDG+P++ S RITT + Sbjct: 1641 PEFQVQPANNITTTTESAFRIGCRSVPPVVTPIISDWLKDGKPIDENDVKSLRITTDTSG 1700 Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 L + +V D G+YTC N+ G + S +T+ Sbjct: 1701 ---QLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTV 1734 Score = 39.1 bits (87), Expect = 0.086 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713 L +GQ Y+ + + P I W +NG L T +F TL+I + +DSG Sbjct: 1748 LAKGQTAYIYCNIS--SYPTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSG 1802 Query: 2714 IYTCKATNLLGEAVSTASIKI 2734 Y C A N LG A + S+ + Sbjct: 1803 QYECTAQNWLGTASANVSVSV 1823 Score = 38.3 bits (85), Expect = 0.15 Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 10/111 (9%) Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT-----WFKNGQRLINS 309 E+ R + ++P + +P N+ + ++ F++ P P VT W K+G+ + + Sbjct: 1631 ELCRVIASIAP-EFQVQPANN-ITTTTESAFRIGCRSVP-PVVTPIISDWLKDGKPIDEN 1687 Query: 310 NKHEI-ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESP 358 + + ITT L V N Q+SD G+YT + +N G I S + V E+P Sbjct: 1688 DVKSLRITTDTSGQLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTVNEAP 1738 Score = 37.5 bits (83), Expect = 0.26 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 7/82 (8%) Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-THDFGYVALDILYTYAEDS 2179 L +G A+ C + P I W NG ++ G RY T++F L I EDS Sbjct: 1748 LAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYNVFTNNF---TLAIYNAVFEDS 1801 Query: 2180 GTYMCKATNKLGEAVNTCTLKV 2201 G Y C A N LG A ++ V Sbjct: 1802 GQYECTAQNWLGTASANVSVSV 1823 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 5/85 (5%) Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEY 2315 +G+TA+ C + P I + NG L+ T +F +L I + V ED+G+Y Sbjct: 1750 KGQTAYIYCNISSY--PTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSGQY 1804 Query: 2316 SVKAINALGHCTSAISMTVTAKGSI 2340 A N LG ++ +S++V SI Sbjct: 1805 ECTAQNWLGTASANVSVSVGMPSSI 1829 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491 L +G+ A+ ++ P + W NG LK G R+ F + F + + + EDSG Sbjct: 1748 LAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYNVFTN-NFTLAIYNAVF-EDSG 1802 Query: 3492 EYLCRAYNNYGEAVTTASMKV 3512 +Y C A N G A S+ V Sbjct: 1803 QYECTAQNWLGTASANVSVSV 1823 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 + +GQTA+ C + PT + W RN +++ T++F ++ I + ED G Sbjct: 1748 LAKGQTAYIYCNISSY--PTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSG 1802 Query: 2448 VYMCRASNLLG 2458 Y C A N LG Sbjct: 1803 QYECTAQNWLG 1813 Score = 36.7 bits (81), Expect = 0.46 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 7/78 (8%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKS-THDFSYVSLDITHTYEEDSGI 2845 +G + CN+ S PT I W N L G RY T++F+ L I + EDSG Sbjct: 1750 KGQTAYIYCNI--SSYPTANITWKRNGAVL-KGPRYNVFTNNFT---LAIYNAVFEDSGQ 1803 Query: 2846 YTCKATNSKGSATTSGSL 2863 Y C A N G+A+ + S+ Sbjct: 1804 YECTAQNWLGTASANVSV 1821 Score = 36.3 bits (80), Expect = 0.61 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 9/102 (8%) Query: 1710 APVFTM-PMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN----RLTTMHD 1764 AP F + P +I A R +P + +WL++G PI+ ++ R+TT Sbjct: 1640 APEFQVQPANNITTTTESAFRIGCRSVPPVVTPIISDWLKDGKPIDENDVKSLRITT-DT 1698 Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806 G + +N V D G YTC N G ++++ST+ ++A Sbjct: 1699 SGQLVVN--NVQRSDFGNYTCVLKNSAG-SISASTIVTVNEA 1737 Score = 36.3 bits (80), Expect = 0.61 Identities = 24/62 (38%), Positives = 30/62 (48%), Gaps = 3/62 (4%) Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKAT 3918 P I W RNG +L G RY V+ F +L I EDSG+Y C A N G + Sbjct: 1764 PTANITWKRNGAVL-KGPRYN-VFTNNF-TLAIYNAVFEDSGQYECTAQNWLGTASANVS 1820 Query: 3919 IS 3920 +S Sbjct: 1821 VS 1822 Score = 36.3 bits (80), Expect = 0.61 Identities = 30/106 (28%), Positives = 42/106 (39%), Gaps = 6/106 (5%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614 G P T PS +++ + +C V W +G + TG + + G Sbjct: 1824 GMPSSIATAPSKTVVNPSQRVTLKCNA--TGQPQPVVTWKKDGVTIKTGPN--RVVEPG- 1878 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660 L IG V + D G+Y C A N ATV + V G I PQ Sbjct: 1879 -TLTIGVVSRADTGMYACIAQNPQNIATVFSSVIVSGPPIINRPPQ 1923 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 5/70 (7%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKT-TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065 PT + W NG V +G R+ T +F L I A ED+G Y C A N +G A Sbjct: 1764 PTANITWKRNGA-VLKGPRYNVFTNNF---TLAIYNAVFEDSGQYECTAQNWLGTASANV 1819 Query: 2066 SVKVDAKSGL 2075 SV V S + Sbjct: 1820 SVSVGMPSSI 1829 Score = 35.5 bits (78), Expect = 1.1 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 7/104 (6%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCR-VEPVGDPTMRIDWFHNGRPFATG---SRVHTLNDF 3750 P F V+ +NI CR V PV P + DW +G+P S T + Sbjct: 1641 PEFQVQPANNITTTTESAFRIGCRSVPPVVTPIIS-DWLKDGKPIDENDVKSLRITTDTS 1699 Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794 G L ++ + D G YTC N GS + + +T + +V Sbjct: 1700 G--QLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTVNEAPRVV 1741 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 1608 TLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661 T + W N LK TNNF L I + + EDSG Y C A N LG A Sbjct: 1765 TANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSGQYECTAQNWLGTA 1815 Score = 34.3 bits (75), Expect = 2.5 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 7/89 (7%) Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498 +V PR V S+ + +GQ + C + +N + W +NG V G R+ + Sbjct: 1733 TVNEAPRVVDFSPSL--LAKGQTAYIYCNISSYPTAN--ITWKRNGA-VLKGPRYNVFTN 1787 Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527 L I + + EDSG Y C A N +GT Sbjct: 1788 --NFTLAIYNAVFEDSGQYECTAQNWLGT 1814 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 5/87 (5%) Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841 L +G+ A+ ++ S PT + W ++G + NF +L I + ED+G Sbjct: 1748 LAKGQTAYIYCNIS--SYPTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSG 1802 Query: 842 SYTVRAVNKLGEAISTASIRVAARSTV 868 Y A N LG A + S+ V S++ Sbjct: 1803 QYECTAQNWLGTASANVSVSVGMPSSI 1829 Score = 33.9 bits (74), Expect = 3.2 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 3/69 (4%) Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799 P + W RNG ++ ++F N + EDSG Y C A N LG A + + Sbjct: 1764 PTANITWKRNGAVLKGPRYNVFTNNFTLAIYNAVF---EDSGQYECTAQNWLGTASANVS 1820 Query: 1800 LFVQSKASL 1808 + V +S+ Sbjct: 1821 VSVGMPSSI 1829 Score = 33.5 bits (73), Expect = 4.3 Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 7/75 (9%) Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THDFGFVTLDINSVVA 2575 PS L +GQ A+ + P+ W NG LK G R+ T++F TL I + V Sbjct: 1745 PSLLAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYNVFTNNF---TLAIYNAVF 1798 Query: 2576 NDAGLYMCKAINRAG 2590 D+G Y C A N G Sbjct: 1799 EDSGQYECTAQNWLG 1813 Score = 33.5 bits (73), Expect = 4.3 Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 7/80 (8%) Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL-TSDFGFVTLDLVDVYERDS 2981 L +GQ ++ + + P I W NG VL+ G R+ + T++F TL + + DS Sbjct: 1748 LAKGQTAYIYCNIS--SYPTANITWKRNGAVLK-GPRYNVFTNNF---TLAIYNAVFEDS 1801 Query: 2982 GIYTCKAYNKRGEAFTSSTV 3001 G Y C A N G A + +V Sbjct: 1802 GQYECTAQNWLGTASANVSV 1821 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 6/98 (6%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 +TV +AP+ ++ +G ++ C + T + W NG +K G R+ + Sbjct: 1732 VTVNEAPRVVDFSPSL-LAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYN-VFT 1786 Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 ++ +V+ EDSG Y C A N LG A + ++ V Sbjct: 1787 NNFTLAIYNAVF-EDSGQYECTAQNWLGTASANVSVSV 1823 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 5/90 (5%) Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114 + +GQ+A+ + S T + W NG + ++F L I + EDSG Sbjct: 1748 LAKGQTAYIYCNIS--SYPTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSG 1802 Query: 1115 VYTVVARNAAGEAQLSASMTVETRSSIDTS 1144 Y A+N G A + S++V SSI T+ Sbjct: 1803 QYECTAQNWLGTASANVSVSVGMPSSIATA 1832 >SB_50799| Best HMM Match : I-set (HMM E-Value=0) Length = 1195 Score = 76.6 bits (180), Expect = 5e-13 Identities = 98/399 (24%), Positives = 151/399 (37%), Gaps = 61/399 (15%) Query: 4430 FEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489 F G P P + W +F N P++ I + + E + + A++R Sbjct: 662 FTCSASGIPTPQLTW---SFSGGNLPNYDIDGNKLSIVNVQNNASYEGN--YTCTADSRA 716 Query: 4490 GTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549 G +A L V +P L + + G V+L + +G W Sbjct: 717 GRTSFTAMLTVHA---------LPKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTY 767 Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609 G + P R + ED L++ + P +G Y C+A N+ G + + +V + Sbjct: 768 KGVPISP--RENVQLEDDNRLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVG- 824 Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIV-AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP--- 4665 I+ PL +K++ EGQ + +C G PLP V WY DK+I Sbjct: 825 ---------------IVVPLPEKVIFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDG 869 Query: 4666 SKYF---QMSRTADEYTLRISEAFPEDEGDYKCVAYN-----SAGRVTVAAKLKVTQPDQ 4717 S+Y +S E TLR++ D G+Y CV N S+G+VTV VT Q Sbjct: 870 SRYSITNNVSGVRLESTLRLNNTRFGDRGNYSCVFKNHGVNKSSGQVTV----HVTPNVQ 925 Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ--MIHEGNN 4775 P L D + F ++ W ++G + PD + I N Sbjct: 926 NITAPVSPRLGDNITLVCVVRGFPDL-------SVNWTKDGRKLVTRPDRKELSITPQEN 978 Query: 4776 AV----LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 AV L I DTG + C A + E S + V Sbjct: 979 AVKFAYLKIWKAKRSDTGGYQCVAYIKQSKDERSTSVTV 1017 Score = 69.7 bits (163), Expect = 5e-11 Identities = 54/194 (27%), Positives = 84/194 (43%), Gaps = 16/194 (8%) Query: 387 EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446 E P+ + + + V + F C +G P P++TW + + N+ I G Sbjct: 638 EVLFKPELELLPKSQTVLVNRTVVFTCSASGIPTPQLTWSFSGGNLP---NYDI----DG 690 Query: 447 NHALMITNV--TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504 N L I NV S G TC A +++G T+F L V ++ K + + TL Sbjct: 691 NK-LSIVNVQNNASYEGNYTCTADSRAGRTSFTAMLTVHALPKIT--KLLNK--TLVAER 745 Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 G V L+ +A G PTP+ W GVPI P +++ D L + + Y+C Sbjct: 746 GSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDDN--RLLILKKVSPVSNGVYRCI 803 Query: 565 AQNVAGSTATRARL 578 A N G+ T +L Sbjct: 804 AYNAEGNDTTETKL 817 Score = 68.1 bits (159), Expect = 2e-10 Identities = 91/354 (25%), Positives = 142/354 (40%), Gaps = 43/354 (12%) Query: 234 VSFRESITKRYVGESDVQISTEIDR-----SLGPVSPPKIAQKPRNSKLQEGADAQFQVQ 288 V F T RY G + + S+ SL PPKIA ++ LQ Sbjct: 406 VVFNVQNTDRYEGSYECEASSRAGNASSSASLTVYDPPKIANVLGDTTLQVRGTLNLTCV 465 Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348 G+P PRV W + G S++ ++ T+++ TL + T+ DSG+YT +A N G Sbjct: 466 ALGDPAPRVYWVREGA---GSSRFKL--TNDNKTLVIFQTEYRDSGNYTCIASNRAGNTS 520 Query: 349 TSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDV----T 404 + + ++ P +V ++ Y + + L +VK + ++ Sbjct: 521 LAKQVDIQVPASVFVDNKTRVYSRNETNATIGCHGNGNPVPLLFWWVKGNKIPEIEALRP 580 Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464 K P VT ++ R Y E+GN+ TN+ L GV Sbjct: 581 ADKSNVVQVTSVAGPMENVTSYLYLRIAGITY------EEAGNYTCNSTNIVL---GVTR 631 Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524 V+R + E F+ L ++ K Q V V R VV A G PTP++TW Sbjct: 632 SVSR--TVEVLFKPELELLPKSQTV---LVNR----------TVVFTCSASGIPTPQLTW 676 Query: 525 QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 G +PN ++ DG ++ + AS Y CTA + AG T+ A L Sbjct: 677 SFSG-GNLPNYDI----DGNKLSIVNVQNNASYEGNYTCTADSRAGRTSFTAML 725 Score = 64.9 bits (151), Expect = 2e-09 Identities = 88/385 (22%), Positives = 147/385 (38%), Gaps = 43/385 (11%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G+P P + W RE S F++ T K+ L+I Q DS + +A NR G + Sbjct: 468 GDPAPRVYWVREG---AGSSRFKL-TNDNKT-LVIFQTEYRDSGNYTCIASNRAGNTSLA 522 Query: 4496 ANLVVEEKRRQGRGGIVPPS-FTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554 + ++ VP S F V + + G ++W G K+ Sbjct: 523 KQVDIQ----------VPASVFVDNKTRVYSRNETNATIGCHGNGNPVPLLFWWVKGNKI 572 Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSG------KYECVAINSAGEARCDAECVVSLPAT 4608 P+I + + A P ++ + + AG C++ +V L T Sbjct: 573 -PEIEALRPADKSNVVQVTSVAGPMENVTSYLYLRIAGITYEEAGNYTCNSTNIV-LGVT 630 Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSK 4667 + + T PE+ K + V + + F+C G P P + W + G L Sbjct: 631 RSVSR--TVEVLFKPELELLPKSQTVLVNRTVVFTCSASGIPTPQLTWSFSGGNL---PN 685 Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727 Y ++ + ++ EG+Y C A + AGR + A L V LP +T L Sbjct: 686 YDIDGNKLSIVNVQNNASY---EGNYTCTADSRAGRTSFTAMLTVHA------LPKITKL 736 Query: 4728 --RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785 + +V G Q Q + P +W +G +P +P + E +N +L++ Sbjct: 737 LNKTLVAERGSNVQLSCQASGDPTPKYKWTYKG--VPISPRENVQLEDDNRLLILKKVSP 794 Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810 G + C A A G T KL+V Sbjct: 795 VSNGVYRCIAYNAEGNDTTETKLIV 819 Score = 60.1 bits (139), Expect = 4e-08 Identities = 47/191 (24%), Positives = 87/191 (45%), Gaps = 17/191 (8%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTL 4680 P +EP+ V G+ F+C++ G P P ++W Y G L + ++ T + + Sbjct: 354 PECAVEPISGDTVV-GKNFTFTCRVEGIPKPDIKWKYNGGPL--NLAHSTINNTLVVFNV 410 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740 + ++ + EG Y+C A + AG + +A L V P + N+ L D + Sbjct: 411 QNTDRY---EGSYECEASSRAGNASSSASLTVYDPPKIANV-----LGDTTLQVRGTLNL 462 Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 P + W+REGA + F++ ++ N L+I T D+G +TC A+ AG Sbjct: 463 TCVALGDPAPRVYWVREGA---GSSRFKLTND--NKTLVIFQTEYRDSGNYTCIASNRAG 517 Query: 4801 QVETSAKLVVK 4811 + ++ ++ Sbjct: 518 NTSLAKQVDIQ 528 Score = 60.1 bits (139), Expect = 4e-08 Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 19/174 (10%) Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-- 459 D GK F CRV G P P++ W N + L + + N+ L++ NV +D Sbjct: 364 DTVVGKNFTFTCRVEGIPKPDIKWKYNGGPLN-------LAHSTINNTLVVFNVQNTDRY 416 Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519 G C A +++G + L V + ++ V +TL VR + L A+G P Sbjct: 417 EGSYECEASSRAGNASSSASLTVYDPPKIAN---VLGDTTLQVR--GTLNLTCVALGDPA 471 Query: 520 PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 PR+ W ++G + ++ D TL I + + D+ Y C A N AG+T+ Sbjct: 472 PRVYWVREGA---GSSRFKLTNDN--KTLVIFQTEYRDSGNYTCIASNRAGNTS 520 Score = 58.4 bits (135), Expect = 1e-07 Identities = 52/174 (29%), Positives = 74/174 (42%), Gaps = 21/174 (12%) Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESG---NHALMITNVTLSD 459 EG+ C G P P VTW+ D+ I D + I N SG L + N D Sbjct: 837 EGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRFGD 896 Query: 460 SGVVTCVARNKS-GETAFQCRLNVIEKEQ-VVAPKFVERFSTLNVREGEPVVLNARAVGT 517 G +CV +N +++ Q ++V Q + AP ++ R G+ + L G Sbjct: 897 RGNYSCVFKNHGVNKSSGQVTVHVTPNVQNITAP--------VSPRLGDNITLVCVVRGF 948 Query: 518 PTPRITWQKDGVPIIPNP---ELRIHTDGGA---STLDIPRAKASDAAWYQCTA 565 P + W KDG ++ P EL I A + L I +AK SD YQC A Sbjct: 949 PDLSVNWTKDGRKLVTRPDRKELSITPQENAVKFAYLKIWKAKRSDTGGYQCVA 1002 Score = 56.0 bits (129), Expect = 7e-07 Identities = 96/423 (22%), Positives = 155/423 (36%), Gaps = 73/423 (17%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P FT+ + + + F G P P I W Q+ S + Sbjct: 67 PEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDALPQGSHQLSNGSLNVAAVY 126 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 V E ++ +A + G A+ +A+L+V+ VPPS + V Q Sbjct: 127 NNVSYE--GLYTCLASSEAGMAQANASLIVD----------VPPSVLSLRGDSTVILEQT 174 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 + L V VYW K+G+ I TL+ + G+Y C A N Sbjct: 175 INLTCVVRA-----VYWKKDGQ-----IITTATLSGNNRTLITQASRVALKGRYACFATN 224 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE-FSCKIVGK 4649 AG D++ ++ PP++ I + G C GK Sbjct: 225 RAGN---DSKSILI-------------TVTVPPKVYVAETVAIFSRGDVNRTLHCHGNGK 268 Query: 4650 PLPTVQWYK--GDKL-----IKPSKYFQMSRTADEYT------------LRISEAFPEDE 4690 P P V W K G + + + F++ + D T LR + ++ Sbjct: 269 PPPRVTWSKVGGASIPFVQSLSVNDNFRVVQIQDNRTTSVLQNVTGILYLRTAGITYKEA 328 Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR-DIVVYEGQPAQFKTQITSKIK 4749 G+Y CVA N G +V++ ++V + A+ P+ D VV G+ F ++ K Sbjct: 329 GNYTCVAENGIGIGSVSSTIEVIFKPEC----AVEPISGDTVV--GKNFTFTCRVEGIPK 382 Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED--TGTFTCRATTAAGQVETSAK 4807 P I+W G + H N L++ N D G++ C A++ AG +SA Sbjct: 383 PDIKWKYNGG------PLNLAHSTINNTLVVFNVQNTDRYEGSYECEASSRAGNASSSAS 436 Query: 4808 LVV 4810 L V Sbjct: 437 LTV 439 Score = 55.6 bits (128), Expect = 9e-07 Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 20/181 (11%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P+F + + + + +G F C +GRP P +TW N +H+ L N S N A + Sbjct: 67 PEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDALPQGSHQ-LSNGSLNVAAV 125 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511 NV S G+ TC+A +++G L +++ V P S L++R V+L Sbjct: 126 YNNV--SYEGLYTCLASSEAGMAQANASL-IVD----VPP------SVLSLRGDSTVILE 172 Query: 512 ARAVGTPTPR-ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 T R + W+KDG II L G TL ++ + Y C A N AG Sbjct: 173 QTINLTCVVRAVYWKKDG-QIITTATL----SGNNRTLITQASRVALKGRYACFATNRAG 227 Query: 571 S 571 + Sbjct: 228 N 228 Score = 53.6 bits (123), Expect = 4e-06 Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 8/134 (5%) Query: 392 PQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 P+ K+ V E G + C+ +G P P+ W I N ++ E N L Sbjct: 731 PKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQL---EDDNRLL 787 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 ++ V+ +GV C+A N G + +L V +V P E+ + EG+P+ L Sbjct: 788 ILKKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIVVP-LPEKVIFM---EGQPLNL 843 Query: 511 NARAVGTPTPRITW 524 A G P P +TW Sbjct: 844 TCAAEGIPLPNVTW 857 Score = 51.2 bits (117), Expect = 2e-05 Identities = 80/323 (24%), Positives = 118/323 (36%), Gaps = 42/323 (13%) Query: 4411 PIFTKKMQPCRVFEH-EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 P TK + V E + + G+P P KW + PI SP + +LI Sbjct: 731 PKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPI--SPRENVQLEDDNRLLI 788 Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529 +++V + V+ +A N G L+V GIV P + V GQ Sbjct: 789 LKKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSV-----GIVVP----LPEKVIFMEGQ 839 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKV-QPD-----IRNKILEEDGTYTLLILEAYPQDSGK 4583 + L G +V W K + Q D I N + TL + D G Sbjct: 840 PLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRFGDRGN 899 Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643 Y CV N G + + V + P Q A P + G I Sbjct: 900 YSCVFKNH-GVNKSSGQVTVHVT-----PNVQNITAPVSPRL-----------GDNITLV 942 Query: 4644 CKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYT-----LRISEAFPEDEGDYKCVA 4697 C + G P +V W K G KL+ ++S T E L+I +A D G Y+CVA Sbjct: 943 CVVRGFPDLSVNWTKDGRKLVTRPDRKELSITPQENAVKFAYLKIWKAKRSDTGGYQCVA 1002 Query: 4698 YNSAGRVTVAAKLKVTQ-PDQAD 4719 Y + + + V + PD+ + Sbjct: 1003 YIKQSKDERSTSVTVLERPDRPE 1025 Score = 50.8 bits (116), Expect = 3e-05 Identities = 87/400 (21%), Positives = 151/400 (37%), Gaps = 64/400 (16%) Query: 4430 FEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489 F +G P P IKW P+ + T + ++ Q + A +R Sbjct: 373 FTCRVEGIPKPDIKWKYNGGPLNLAHS----TINNTLVVFNVQNTDRYEGSYECEASSRA 428 Query: 4490 GTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549 G A SA+L V + PP + + + L G VYW++ Sbjct: 429 GNASSSASLTVYD----------PPKIANVLGDTTLQVRGTLNLTCVALGDPAPRVYWVR 478 Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609 G R K+ ++ T L+I + +DSG Y C+A N AG + + +PA+ Sbjct: 479 EGAGSS---RFKLTNDNKT--LVIFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPAS- 532 Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQA-IEFSCKIVGKPLPTVQWY-KGDKL----- 4662 + K ++ + + C G P+P + W+ KG+K+ Sbjct: 533 ---------------VFVDNKTRVYSRNETNATIGCHGNGNPVPLLFWWVKGNKIPEIEA 577 Query: 4663 IKP---SKYFQMSRTA---DEYT----LRISEAFPEDEGDYKCVAYNSAGRVT--VAAKL 4710 ++P S Q++ A + T LRI+ E+ G+Y C + N VT V+ + Sbjct: 578 LRPADKSNVVQVTSVAGPMENVTSYLYLRIAGITYEEAGNYTCNSTNIVLGVTRSVSRTV 637 Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMI 4770 +V + + LP + V + F + P + W G P++ + Sbjct: 638 EVLFKPELELLP-----KSQTVLVNRTVVFTCSASGIPTPQLTWSFSGG---NLPNYDI- 688 Query: 4771 HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 +GN ++ G +TC A + AG+ +A L V Sbjct: 689 -DGNKLSIVNVQNNASYEGNYTCTADSRAGRTSFTAMLTV 727 Score = 50.4 bits (115), Expect = 3e-05 Identities = 55/240 (22%), Positives = 94/240 (39%), Gaps = 35/240 (14%) Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535 +++ + VAEN G S+ + V I P + + + G+ Sbjct: 326 KEAGNYTCVAENGIGIGSVSSTIEV----------IFKPECAVEPISGDTVVGKNFTFTC 375 Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595 +V G D+ W NG + ++ + + + T + ++ + G YEC A + AG A Sbjct: 376 RVEGIPKPDIKWKYNGGPL--NLAHSTI--NNTLVVFNVQNTDRYEGSYECEASSRAGNA 431 Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655 A V PP+I L D + + +C +G P P V Sbjct: 432 SSSASLTVY----------------DPPKIANVLGDTTLQVRGTLNLTCVALGDPAPRVY 475 Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715 W + S F++ T D TL I + D G+Y C+A N AG ++A ++ + P Sbjct: 476 WVREGA---GSSRFKL--TNDNKTLVIFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVP 530 Score = 50.0 bits (114), Expect = 5e-05 Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 17/170 (10%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141 I+W YNG + +H + +VV + T + G+Y C A+++ G A S L Sbjct: 385 IKWKYNGGPLNLAH---STINNTLVVFNVQNTDRYE-GSYECEASSRAGNASSSASLTVY 440 Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201 D K T +Q + G T V + DP ++ W G S+R K Sbjct: 441 DPPKIANVLGDTTLQ-VRGT-------LNLTCVALGDPAPRVYWVREGAG---SSRFKLT 489 Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251 +D +V I T+ DSG Y C A N+ G ++ V++++ Sbjct: 490 NDNKTLV--IFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPASVFVDN 537 Score = 48.8 bits (111), Expect = 1e-04 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+ + PR+ +++G F SG P+PR+TW NG + H++ + Sbjct: 67 PEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDALPQGSHQLSNGSLNVAAVY 126 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 N S G YT LA + G + L V+ P Sbjct: 127 NNV--SYEGLYTCLASSEAGMAQANASLIVDVP 157 Score = 48.0 bits (109), Expect = 2e-04 Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 18/142 (12%) Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG-LK 3162 G++ L G ++G Y+C A N G +S +E + K + ++ I G Sbjct: 314 GILYLRTAGITYKEAGNYTCVAENGIGIGSVSSTIEVIFKPE-------CAVEPISGDTV 366 Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMR--HSTRIKTVSDFGFVVLDIAYTQNHDSG 3220 G++ F C V + PD+K W +NG P+ HST T+ VV ++ T ++ G Sbjct: 367 VGKNFTFTCRVEGIPKPDIK--WKYNGGPLNLAHSTINNTL-----VVFNVQNTDRYE-G 418 Query: 3221 EYVCRAYNKYGEDFTRATINCY 3242 Y C A ++ G + A++ Y Sbjct: 419 SYECEASSRAGNASSSASLTVY 440 Score = 46.8 bits (106), Expect = 4e-04 Identities = 64/271 (23%), Positives = 104/271 (38%), Gaps = 43/271 (15%) Query: 4547 WLKNGKKVQPD-IRNKILEEDGTYTLLILEAYPQ--DSGKYECVAINSAGEARCDAECVV 4603 W K+G V PD +N + E ++ + D+G Y C A+N+A + + + Sbjct: 3 WSKDGSAVAPDRYQNTEVSETNISSVFEFSSGTTYADAGNYTCHAVNNADDKGTVSAVIQ 62 Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKL 4662 L PE + + + +G + F C G+P P + W Y G Sbjct: 63 VL---------------FEPEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDA 107 Query: 4663 IKPSKYFQMSRTADEYTLRISEAF--PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720 + P Q+S +L ++ + EG Y C+A + AG A L V P Sbjct: 108 L-PQGSHQLSNG----SLNVAAVYNNVSYEGLYTCLASSEAGMAQANASLIVDVP----- 157 Query: 4721 LPALTPLR-DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779 P++ LR D V Q +T ++ + W ++G +I GNN L+ Sbjct: 158 -PSVLSLRGDSTVILEQ----TINLTCVVR-AVYWKKDGQIITTA-----TLSGNNRTLI 206 Query: 4780 IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 + G + C AT AG S + V Sbjct: 207 TQASRVALKGRYACFATNRAGNDSKSILITV 237 Score = 46.8 bits (106), Expect = 4e-04 Identities = 51/186 (27%), Positives = 76/186 (40%), Gaps = 31/186 (16%) Query: 413 CRVTGRPYPEVTWF--------------INDR----QIRDDYNHKILVNESGNHALMITN 454 C G+P P VTW +ND QI+D+ +L N +G L Sbjct: 263 CHGNGKPPPRVTWSKVGGASIPFVQSLSVNDNFRVVQIQDNRTTSVLQNVTGILYLRTAG 322 Query: 455 VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514 +T ++G TCVA N G + + VI K + VE S V G+ R Sbjct: 323 ITYKEAGNYTCVAENGIGIGSVSSTIEVIFKPECA----VEPISGDTV-VGKNFTFTCRV 377 Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD--AAWYQCTAQNVAGST 572 G P P I W+ +G P L + +TL + + +D Y+C A + AG+ Sbjct: 378 EGIPKPDIKWKYNGGP------LNLAHSTINNTLVVFNVQNTDRYEGSYECEASSRAGNA 431 Query: 573 ATRARL 578 ++ A L Sbjct: 432 SSSASL 437 Score = 46.0 bits (104), Expect = 8e-04 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 5/99 (5%) Query: 1305 ITVMQAPQFSRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363 +TV P+ ++ L+ E G+NV L C Q GD T + +W G PI R Sbjct: 725 LTVHALPKITKLLNKTLVAERGSNVQLSC--QASGDPTPKYKWTYKGVPISP--RENVQL 780 Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 E D L L V P +GVY C A N G T L V Sbjct: 781 EDDNRLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIV 819 Score = 44.8 bits (101), Expect = 0.002 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%) Query: 49 TTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK 108 T +S R TA P I + + K +G N + + G+PTP WT K Sbjct: 709 TCTADSRAGRTSFTAMLTVHALPKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYK 768 Query: 109 KAPLVECNKYSMRYNEQTGDVS--LLIKQIGPGDEGEYTCTARNQYG 153 P+ S R N Q D + L++K++ P G Y C A N G Sbjct: 769 GVPI------SPRENVQLEDDNRLLILKKVSPVSNGVYRCIAYNAEG 809 Score = 42.3 bits (95), Expect = 0.009 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 10/91 (10%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN-KPLPSGTRYKSTHDFSYVSLD 2834 F H + K+G+++ F C S P +I W +N LP G+ H S SL+ Sbjct: 69 FTRHPRSQTIKQGNHVTFGCAA--SGRPQPRITWLYNGGDALPQGS-----HQLSNGSLN 121 Query: 2835 ITHTYEEDS--GIYTCKATNSKGSATTSGSL 2863 + Y S G+YTC A++ G A + SL Sbjct: 122 VAAVYNNVSYEGLYTCLASSEAGMAQANASL 152 Score = 41.5 bits (93), Expect = 0.016 Identities = 16/50 (32%), Positives = 27/50 (54%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 P F P + T+++G F C +G P+PR+ WL NG + ++L+ Sbjct: 67 PEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDALPQGSHQLS 116 Score = 40.7 bits (91), Expect = 0.028 Identities = 54/280 (19%), Positives = 94/280 (33%), Gaps = 24/280 (8%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP + + G G+P P V W R+ A S R+ + + Sbjct: 442 PPKIANVLGDTTLQVRGTLNLTCVALGDPAPRVYWVREGAG-------SSRFKLTNDNKT 494 Query: 131 LLIKQIGPGDEGEYTCTARNQYG----------EAICSVYIQPEGXXXXXXXXXXXXXYR 180 L+I Q D G YTC A N+ G + SV++ + Sbjct: 495 LVIFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPASVFVDNKTRVYSRNETNATIGCH 554 Query: 181 HVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESI 240 V + +G + + +N +S + Y LR Sbjct: 555 GNGNPVPLLFWWVKGNKIPEIEALRPADKSNVVQVTSVAGPMENVTSYLYLRIAGITYEE 614 Query: 241 TKRYVGESD---VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297 Y S + ++ + R++ + P++ P++ + F SG P P++ Sbjct: 615 AGNYTCNSTNIVLGVTRSVSRTVEVLFKPELELLPKSQTVLVNRTVVFTCSASGIPTPQL 674 Query: 298 TWFKNGQRL----INSNKHEIITTHNHTTLRVRNTQKSDS 333 TW +G L I+ NK I+ N+ + T +DS Sbjct: 675 TWSFSGGNLPNYDIDGNKLSIVNVQNNASYEGNYTCTADS 714 Score = 40.3 bits (90), Expect = 0.037 Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 7/116 (6%) Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615 +PP+ D L + + C + + D + RV W G SR K ND + Sbjct: 441 DPPKIANVLGDTTLQVRGTLNLTC--VALGDPAPRVYWVREGAG---SSRFKLTNDNKTL 495 Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES 3671 + I RD+G YTC A+NR G +++ ++ ++ + ++ + + ++ T + Sbjct: 496 V--IFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPASVFVDNKTRVYSRNETNA 549 Score = 39.9 bits (89), Expect = 0.049 Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 5/90 (5%) Query: 445 SGNHALMITNVT-LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503 SGN+ +IT + ++ G C A N++G + + V +V + V FS +V Sbjct: 199 SGNNRTLITQASRVALKGRYACFATNRAGNDSKSILITVTVPPKVYVAETVAIFSRGDVN 258 Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIP 533 L+ G P PR+TW K G IP Sbjct: 259 R----TLHCHGNGKPPPRVTWSKVGGASIP 284 Score = 39.9 bits (89), Expect = 0.049 Identities = 60/291 (20%), Positives = 105/291 (36%), Gaps = 22/291 (7%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P E + K+ F G PTP ++W+ L Y+ +S+ Sbjct: 643 PELELLPKSQTVLVNRTVVFTCSASGIPTPQLTWSFSGGNLPN-------YDIDGNKLSI 695 Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191 + Q EG YTCTA ++ G + + S + Sbjct: 696 VNVQNNASYEGNYTCTADSRAGRTSFTAMLTVHALPKITKLLNKTLVAERGSNV--QLSC 753 Query: 192 GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV-DTFEYRLLREVSFRESITKRYVGESDV 250 G T + + T K G S ++ ++ D +L++VS + R + + Sbjct: 754 QASGDPTPKYKWTYK-----GVPISPRENVQLEDDNRLLILKKVSPVSNGVYRCIAYNAE 808 Query: 251 QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310 T + + VS + P EG G P P VTW+ + + ++ Sbjct: 809 GNDTTETKLIVHVSVGIVVPLPEKVIFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTD 868 Query: 311 KHEIITTHN------HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 T+N +TLR+ NT+ D G+Y+ + +N +G +SG + V Sbjct: 869 GSRYSITNNVSGVRLESTLRLNNTRFGDRGNYSCVFKN-HGVNKSSGQVTV 918 Score = 38.7 bits (86), Expect = 0.11 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 3/92 (3%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P T + VAE + ++ + GDP + +W GVPI + D + L Sbjct: 731 PKITKLLNKTLVAE-RGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDDNRLLIL 789 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802 K V+P +G Y C A N G T + L V Sbjct: 790 --KKVSPVSNGVYRCIAYNAEGNDTTETKLIV 819 Score = 38.3 bits (85), Expect = 0.15 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 10/86 (11%) Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED--SGE 1916 G++ + CR+E P P+ ++W +NG L H T N+ L + V D G Sbjct: 368 GKNFTFTCRVEGIPKPD--IKWKYNGGPLNLAHS--TINN----TLVVFNVQNTDRYEGS 419 Query: 1917 YTCKAINNLGQAVSSIRLNVQSKESI 1942 Y C+A + G A SS L V I Sbjct: 420 YECEASSRAGNASSSASLTVYDPPKI 445 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 4/81 (4%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 +V + G N+ C + S DPT K +W + P+ + D L + Sbjct: 741 LVAERGSNVQLSC--QASGDPTPKYKWTYKGVPISPRENVQLEDDNRL--LILKKVSPVS 796 Query: 2843 SGIYTCKATNSKGSATTSGSL 2863 +G+Y C A N++G+ TT L Sbjct: 797 NGVYRCIAYNAEGNDTTETKL 817 Score = 37.5 bits (83), Expect = 0.26 Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 5/73 (6%) Query: 938 DSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997 + RV ++D R +T G + L +T +AG+YTC A N IG + S+ Sbjct: 292 NDNFRVVQIQDNRTTSVLQNVT-----GILYLRTAGITYKEAGNYTCVAENGIGIGSVSS 346 Query: 998 NLTIVTKKDIIAE 1010 + ++ K + E Sbjct: 347 TIEVIFKPECAVE 359 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 6/76 (7%) Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847 G N F C VE P +K W +N PL ST + + V ++ +T + G Y Sbjct: 368 GKNFTFTCRVEGIPKPDIK--WKYNGGPLNLA---HSTINNTLVVFNVQNT-DRYEGSYE 421 Query: 2848 CKATNSKGSATTSGSL 2863 C+A++ G+A++S SL Sbjct: 422 CEASSRAGNASSSASL 437 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 7/80 (8%) Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG-YVALNMKYVNPEDSGTYTCRAINELGE 1793 + +GDP RV W+R G S+R +D V +Y DSG YTC A N G Sbjct: 465 VALGDPAPRVYWVREGA---GSSRFKLTNDNKTLVIFQTEY---RDSGNYTCIASNRAGN 518 Query: 1794 AVTSSTLFVQSKASLQLESQ 1813 + + +Q AS+ ++++ Sbjct: 519 TSLAKQVDIQVPASVFVDNK 538 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/101 (25%), Positives = 39/101 (38%), Gaps = 4/101 (3%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P+ T + + G V C+ GDPT + W + G P + V +D + Sbjct: 731 PKITKLLNKTLVAERGSNVQLSCQAS--GDPTPKYKWTYKGVPISPRENVQLEDDNRLLI 788 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795 L + G Y C A N G+ TT K+ IV+ Sbjct: 789 L--KKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIVV 827 Score = 37.1 bits (82), Expect = 0.35 Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 10/107 (9%) Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752 +PP+ + D + G ++ C +GDP R+ W G A SR ND Sbjct: 441 DPPKIANVLGDTT-LQVRGTLNLTCVA--LGDPAPRVYWVREG---AGSSRFKLTNDNKT 494 Query: 3753 IAL-DIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798 + + +Y RD+G YTC A+N+ G+ + ++ + ++++ Sbjct: 495 LVIFQTEY---RDSGNYTCIASNRAGNTSLAKQVDIQVPASVFVDNK 538 Score = 36.7 bits (81), Expect = 0.46 Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 9/127 (7%) Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293 ++++E+ V E+ + I + + ++ + P+ A +P + G + F ++ G P Sbjct: 323 ITYKEAGNYTCVAENGIGIGS-VSSTIEVIFKPECAVEPISGDTVVGKNFTFTCRVEGIP 381 Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD--SGHYTLLAENPNGCIVTSG 351 +P + W NG L + H I + TL V N Q +D G Y A + G +S Sbjct: 382 KPDIKWKYNGGPL--NLAHSTI----NNTLVVFNVQNTDRYEGSYECEASSRAGNASSSA 435 Query: 352 YLAVESP 358 L V P Sbjct: 436 SLTVYDP 442 Score = 36.7 bits (81), Expect = 0.46 Identities = 29/124 (23%), Positives = 49/124 (39%), Gaps = 8/124 (6%) Query: 3262 ELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321 E S G + S +PPK + D T V G V + DP +V W Sbjct: 423 EASSRAGNASSSASLTVYDPPKIANVLGDTTLQVRGT---LNLTCVALGDPAPRVYWVRE 479 Query: 3322 GKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLI 3381 G R++ +D ++ I +SG Y C+A+N+ G S + ++ Sbjct: 480 GAG---SSRFKLTNDNKTLV--IFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPASVF 534 Query: 3382 LDSQ 3385 +D++ Sbjct: 535 VDNK 538 Score = 36.7 bits (81), Expect = 0.46 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 5/82 (6%) Query: 1997 LEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056 L T + DP RV W G RFK T D L I D+G Y C A+N Sbjct: 460 LNLTCVALGDPAPRVYWVREGAG---SSRFKLTND--NKTLVIFQTEYRDSGNYTCIASN 514 Query: 2057 AVGEAVTTSSVKVDAKSGLYLD 2078 G V + + +++D Sbjct: 515 RAGNTSLAKQVDIQVPASVFVD 536 Score = 36.7 bits (81), Expect = 0.46 Identities = 28/129 (21%), Positives = 50/129 (38%), Gaps = 9/129 (6%) Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178 G Y+C A ++ G+ + L + P+ T + + G + C D Sbjct: 706 GNYTCTADSRAGRTSFTAML-----TVHALPKITKLLNKTLVAERGSNVQLSCQAS--GD 758 Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRAT 3238 P K +W + G P+ ++ D ++L ++ G Y C AYN G D T Sbjct: 759 PTPKYKWTYKGVPISPRENVQLEDDNRLLILKKVSPVSN--GVYRCIAYNAEGNDTTETK 816 Query: 3239 INCYGKGGV 3247 + + G+ Sbjct: 817 LIVHVSVGI 825 Score = 36.3 bits (80), Expect = 0.61 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 6/100 (6%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW-YRNGKLLPSGHRYRTVYDMGFVS 3888 P+F +S T+++ V F C + P RI W Y G LP G G ++ Sbjct: 67 PEFTRHPRSQTIKQGNHVTFGCAASGRPQP--RITWLYNGGDALPQGSHQ---LSNGSLN 121 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928 + +Y G Y C A ++ G A++ P ++ Sbjct: 122 VAAVYNNVSYEGLYTCLASSEAGMAQANASLIVDVPPSVL 161 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F +S T +G + F G P +I WL NG +A + + G +++ Sbjct: 67 PEFTRHPRSQTIKQGNHVTFGCAAS--GRPQPRITWLYNGG--DALPQGSHQLSNGSLNV 122 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + N+ G YTC A S G+A+ A L V Sbjct: 123 AAVYNNVSYEGLYTCLASSEAGMAQANASLIV 154 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 6/81 (7%) Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765 D G F CRVE G P I W +NG P + H+ + + ++ R Sbjct: 364 DTVVGKNFTFTCRVE--GIPKPDIKWKYNGGPL---NLAHSTINNTLVVFNVQNT-DRYE 417 Query: 3766 GEYTCRATNKWGSATTTAKIT 3786 G Y C A+++ G+A+++A +T Sbjct: 418 GSYECEASSRAGNASSSASLT 438 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 6/78 (7%) Query: 3295 VEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGE 3354 V G++ F R+ + PD+K W YNG L H T ++ +V+ ++ + G Sbjct: 366 VVGKNFTFTCRVEGIPKPDIK--WKYNGGPLNLAHS--TINNT-LVVFNVQNT-DRYEGS 419 Query: 3355 YECVATNKLGRDSTKANL 3372 YEC A+++ G S+ A+L Sbjct: 420 YECEASSRAGNASSSASL 437 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/62 (38%), Positives = 30/62 (48%), Gaps = 5/62 (8%) Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999 DP ++ W G SRFKLT+D TL + RDSG YTC A N+ G + Sbjct: 469 DPAPRVYWVREGA---GSSRFKLTNDNK--TLVIFQTEYRDSGNYTCIASNRAGNTSLAK 523 Query: 3000 TV 3001 V Sbjct: 524 QV 525 Score = 35.5 bits (78), Expect = 1.1 Identities = 31/126 (24%), Positives = 47/126 (37%), Gaps = 2/126 (1%) Query: 1545 STQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPV 1604 + QN A E S+ RT +T A T L N + + ++ + Sbjct: 697 NVQNNASYEGNYTCTADSRAGRTSFTAMLTVHALPKITKLLNKTLVAERGSNVQLSCQAS 756 Query: 1605 SDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664 D T K +W + P+ ++ + L +S P +G Y C A NA G T Sbjct: 757 GDPTPKYKWTYKGVPISPRENVQLEDDNRLLILKKVS--PVSNGVYRCIAYNAEGNDTTE 814 Query: 1665 GIAIVH 1670 IVH Sbjct: 815 TKLIVH 820 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 3/96 (3%) Query: 913 TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIK 972 T + ++ + E G ++ + + GD T + +W G P+ S R L +K Sbjct: 734 TKLLNKTLVAERG-SNVQLSCQASGDPTPKYKWTYKGVPI--SPRENVQLEDDNRLLILK 790 Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008 V+ G Y C AYNA G TT L + I+ Sbjct: 791 KVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIV 826 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 5/58 (8%) Query: 2533 VPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 V +GDP+ R W G SRF+ T+D TL I D+G Y C A NRAG Sbjct: 465 VALGDPAPRVYWVREGAG---SSRFKLTNDNK--TLVIFQTEYRDSGNYTCIASNRAG 517 Score = 35.1 bits (77), Expect = 1.4 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 5/98 (5%) Query: 3976 VTQIQSQTSLVEM-ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMN 4034 +T++ ++T + E + CQ + GDP K +W + G P+ + D + + Sbjct: 733 ITKLLNKTLVAERGSNVQLSCQAS--GDPTPKYKWTYKGVPISPRENVQLEDDNRLLILK 790 Query: 4035 FGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072 V P +G Y C A N G D T+ + GIV Sbjct: 791 --KVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIV 826 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 6/78 (7%) Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183 G F CRVE I P I W +NG + H +T + V ++ T + G+Y Sbjct: 368 GKNFTFTCRVEGIPKPD--IKWKYNGGPLNLAH---STINNTLVVFNVQNTDRYE-GSYE 421 Query: 2184 CKATNKLGEAVNTCTLKV 2201 C+A+++ G A ++ +L V Sbjct: 422 CEASSRAGNASSSASLTV 439 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932 DP RV W G R++ +ND L I DSG YTC A N G + Sbjct: 469 DPAPRVYWVREGA---GSSRFKLTNDN--KTLVIFQTEYRDSGNYTCIASNRAGNTSLAK 523 Query: 1933 RLNVQSKESIIRDSQ 1947 ++++Q S+ D++ Sbjct: 524 QVDIQVPASVFVDNK 538 Score = 34.3 bits (75), Expect = 2.5 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 8/94 (8%) Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300 P V + G T V GK F C+VE + P+ I++ +NG L A H T + V Sbjct: 354 PECAVEPISGDTVV--GKNFTFTCRVEGIPKPD--IKWKYNGGPLNLA---HSTINNTLV 406 Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 ++Q+ G Y +A + G+ +S+ S+TV Sbjct: 407 VFNVQN-TDRYEGSYECEASSRAGNASSSASLTV 439 Score = 34.3 bits (75), Expect = 2.5 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 14/96 (14%) Query: 3558 PEFTTTP--SDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG 3613 PE P D ++ +N + F CR+ IP D ++W +NG PL TIN+ Sbjct: 354 PECAVEPISGDTVVGKNFT--FTCRVEGIPKPD----IKWKYNGGPLNLAH--STINNT- 404 Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 V+ + R G Y C+A++R G A+ S L V Sbjct: 405 LVVFNVQNT-DRYEGSYECEASSRAGNASSSASLTV 439 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 7/86 (8%) Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692 VY PP+ L T G ++ +GDP ++ W++ G SSRF Sbjct: 439 VYDPPKIANVLGDTTLQVRGTLNLTC--VALGDPAPRVYWVREGAG---SSRFK--LTND 491 Query: 693 YISLDMLSLNIQDSGEYTCRAVSATG 718 +L + +DSG YTC A + G Sbjct: 492 NKTLVIFQTEYRDSGNYTCIASNRAG 517 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 4/91 (4%) Query: 3567 LILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRD 3626 L+ S+ C+ D + + +W + G P+ V+ +D +IL+ V Sbjct: 741 LVAERGSNVQLSCQAS--GDPTPKYKWTYKGVPISPRENVQLEDDNRLLILK--KVSPVS 796 Query: 3627 AGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657 G+Y C A N G T KL V GI++ Sbjct: 797 NGVYRCIAYNAEGNDTTETKLIVHVSVGIVV 827 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 7/95 (7%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGV-TLTTGARLKSTFDFGLV 2700 P FT H +S + +G HV R P +I W NG L G+ S + Sbjct: 67 PEFTRHPRS-QTIKQGNHVTFGCAASGRPQP--RITWLYNGGDALPQGSHQLSNGSLNVA 123 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 + N++ + G+YTC A++ G A + AS+ ++ Sbjct: 124 AV-YNNVSYE--GLYTCLASSEAGMAQANASLIVD 155 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 8/94 (8%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 PEFT P + + + F C R+ W +NG L + N L Sbjct: 67 PEFTRHPRSQTIKQGNHVTFGCAAS--GRPQPRITWLYNGGDALPQGSHQLSNGS----L 120 Query: 3618 EIGGVYQRDA--GLYTCKATNRHGEATVSCKLQV 3649 + VY + GLYTC A++ G A + L V Sbjct: 121 NVAAVYNNVSYEGLYTCLASSEAGMAQANASLIV 154 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 5/91 (5%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P FT + + +G V F C G P RI W +NG A H L++ G + Sbjct: 67 PEFTRHPRSQT-IKQGNHVTFGCAAS--GRPQPRITWLYNGGD-ALPQGSHQLSN-GSLN 121 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 + Y G YTC A+++ G A A + Sbjct: 122 VAAVYNNVSYEGLYTCLASSEAGMAQANASL 152 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 9/79 (11%) Query: 3112 GTKTTDSGTYSCRATNKW-GQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170 GT D+G Y+C A N + +S ++ + +P FT H ++ + +K G F Sbjct: 34 GTTYADAGNYTCHAVNNADDKGTVSAVIQVL-----FEPEFTRHPRS-QTIKQGNHVTFG 87 Query: 3171 CTVVPVDDPDMKIEWYHNG 3189 C P +I W +NG Sbjct: 88 CAA--SGRPQPRITWLYNG 104 Score = 33.5 bits (73), Expect = 4.3 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 2/51 (3%) Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLT 4160 + V LP+ V EG+ C G P P V W I +GSRY +T Sbjct: 825 IVVPLPEKVIFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSIT 875 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 6/73 (8%) Query: 1738 GDPKLRVEWLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795 G P+ R+ WL NG + S++L+ G + + Y N G YTC A +E G A Sbjct: 92 GRPQPRITWLYNGGDALPQGSHQLSN----GSLNVAAVYNNVSYEGLYTCLASSEAGMAQ 147 Query: 1796 TSSTLFVQSKASL 1808 +++L V S+ Sbjct: 148 ANASLIVDVPPSV 160 Score = 33.1 bits (72), Expect = 5.7 Identities = 17/50 (34%), Positives = 26/50 (52%) Query: 3610 NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659 N G + L G+ ++AG YTC A N G +VS ++V + +EP Sbjct: 311 NVTGILYLRTAGITYKEAGNYTCVAENGIGIGSVSSTIEVIFKPECAVEP 360 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 4/91 (4%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 PK IT++ + T LV + ++ + DP K +W Y G + + D ++I Sbjct: 731 PK-ITKLLNKT-LVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDDNRLLI 788 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372 L + ++G Y C+A N G D+T+ L Sbjct: 789 LKKVS--PVSNGVYRCIAYNAEGNDTTETKL 817 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 8/100 (8%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 I V+ P+F+R + +G +V C G R+ W NG + +++ Sbjct: 61 IQVLFEPEFTRHPRSQTIKQGNHVTFGCAAS--GRPQPRITWLYNGGDALP----QGSHQ 114 Query: 1365 FDYVALDLLSVYPEDS--GVYTCQATNQLGEAVTSCALRV 1402 +L++ +VY S G+YTC A+++ G A + +L V Sbjct: 115 LSNGSLNVAAVYNNVSYEGLYTCLASSEAGMAQANASLIV 154 Score = 32.3 bits (70), Expect = 9.9 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 6/102 (5%) Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360 V I V+ P+ + + +TV G N CR++ G ++W NG P+ H Sbjct: 344 VSSTIEVIFKPECAVEPISGDTVVGKNFTFTCRVE--GIPKPDIKWKYNGGPLNLAHS-- 399 Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 V ++ + G Y C+A+++ G A +S +L V Sbjct: 400 -TINNTLVVFNVQNT-DRYEGSYECEASSRAGNASSSASLTV 439 Score = 32.3 bits (70), Expect = 9.9 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 11/86 (12%) Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVL--QSGHRYRTSNDFGFAALDIL-----TVY 1910 EGQ + C E P PN V WY K++ G RY +N+ L+ T + Sbjct: 837 EGQPLNLTCAAEGIPLPN--VTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRF 894 Query: 1911 GEDSGEYTCKAINNLGQAVSSIRLNV 1936 G D G Y+C N G SS ++ V Sbjct: 895 G-DRGNYSC-VFKNHGVNKSSGQVTV 918 >SB_40971| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 828 Score = 75.8 bits (178), Expect = 8e-13 Identities = 56/169 (33%), Positives = 80/169 (47%), Gaps = 15/169 (8%) Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470 F C +G P P + W D + ++K+L GN L++ N TL D+G+ C A N Sbjct: 228 FHCAASGVPKPVLIWSKVDGAPLMESSYKML----GNGRLVLENTTLEDAGLYECKAINL 283 Query: 471 SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL-NARAVGTPTPRITWQKDGV 529 GE++ RL V V P V+EG+ V+L G P P I W + Sbjct: 284 LGESSATMRLVV-----TVPPSVSIDIGPTYVQEGDNVMLPKCHVTGFPLPEINWTRSAG 338 Query: 530 PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + P R+ T GG L I A+A+D+ Y C+A+N GST R +L Sbjct: 339 QL---PRRRVMTSGG--QLSILAARANDSGDYFCSARNHIGSTIARTQL 382 Score = 54.4 bits (125), Expect = 2e-06 Identities = 50/155 (32%), Positives = 68/155 (43%), Gaps = 18/155 (11%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C VTG P PE+ W + Q+ + V SG L I +DSG C ARN G Sbjct: 321 CHVTGFPLPEINWTRSAGQLP-----RRRVMTSGGQ-LSILAARANDSGDYFCSARNHIG 374 Query: 473 ETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREGEPVVLNARAVGTPTPR-ITWQKDGVP 530 T + +L V P+F + +L G V+L +A G+P P ITW + G Sbjct: 375 STIARTQLVVF-----ALPRFIISPPKSLKAEVGSDVILPCKAYGSPPPLVITWHRHG-K 428 Query: 531 IIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 IP + DG +D+ A D+ Y CTA Sbjct: 429 SIPQERSGV-IDGVLRLIDVTTA---DSGVYVCTA 459 Score = 50.8 bits (116), Expect = 3e-05 Identities = 69/278 (24%), Positives = 104/278 (37%), Gaps = 42/278 (15%) Query: 4426 EQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484 + A F G P P++ W + + P+ S + L++ +ED+ ++ Sbjct: 224 DTAVFHCAASGVPKPVLIWSKVDGAPLMESS----YKMLGNGRLVLENTTLEDAGLYECK 279 Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT-KVTGTKPI 4543 A N G + + LVV VPPS ++ V G V L VTG Sbjct: 280 AINLLGESSATMRLVVT----------VPPSVSIDIGPTYVQEGDNVMLPKCHVTGFPLP 329 Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603 ++ W ++ ++ R +++ G L IL A DSG Y C A N G + VV Sbjct: 330 EINWTRSAGQLP---RRRVMTSGGQ--LSILAARANDSGDYFCSARNHIGSTIARTQLVV 384 Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKL 4662 P II P K G + CK G P P + W++ K Sbjct: 385 FA---------------LPRFIISPPKSLKAEVGSDVILPCKAYGSPPPLVITWHRHGKS 429 Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700 I + S D LR+ + D G Y C A +S Sbjct: 430 IPQER----SGVIDG-VLRLIDVTTADSGVYVCTATSS 462 Score = 50.0 bits (114), Expect = 5e-05 Identities = 49/192 (25%), Positives = 69/192 (35%), Gaps = 15/192 (7%) Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679 +AP I+ P I A A+ F C G P P + W K D ++M Sbjct: 207 SAPNAIVSPALITINASDTAV-FHCAASGVPKPVLIWSKVDGAPLMESSYKMLGNG---R 262 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739 L + ED G Y+C A N G + +L VT P + V EG Sbjct: 263 LVLENTTLEDAGLYECKAINLLGESSATMRLVVTVPPSVS-----IDIGPTYVQEGDNVM 317 Query: 4740 F-KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798 K +T P I W R +P +++ G +L D+G + C A Sbjct: 318 LPKCHVTGFPLPEINWTRSAGQLPRR---RVMTSGGQLSILAARA--NDSGDYFCSARNH 372 Query: 4799 AGQVETSAKLVV 4810 G +LVV Sbjct: 373 IGSTIARTQLVV 384 Score = 41.9 bits (94), Expect = 0.012 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 10/115 (8%) Query: 3825 IVSTPPKFITQIKSHTVEESEGVRF-ECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883 +V+ PP I V+E + V +C V P+ I W R+ LP R R + Sbjct: 294 VVTVPPSVSIDIGPTYVQEGDNVMLPKCHVTGFPLPE--INWTRSAGQLP---RRRVMTS 348 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938 G L IL A DSG+Y C A N G + + LP I+ P+ +K Sbjct: 349 GG--QLSILAARANDSGDYFCSARNHIGSTIARTQLVVFALPRFII--SPPKSLK 399 Score = 39.9 bits (89), Expect = 0.049 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 5/90 (5%) Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTL 548 AP + + + + + V + A G P P + W K DG P++ + + G L Sbjct: 208 APNAIVSPALITINASDTAVFHCAASGVPKPVLIWSKVDGAPLMESSYKML----GNGRL 263 Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + DA Y+C A N+ G ++ RL Sbjct: 264 VLENTTLEDAGLYECKAINLLGESSATMRL 293 Score = 37.1 bits (82), Expect = 0.35 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 8/86 (9%) Query: 1852 GPTKLSEGQSAHY-ECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVY 1910 GPT + EG + +C + +P P + W + L R TS L IL Sbjct: 306 GPTYVQEGDNVMLPKCHVTGFPLPE--INWTRSAGQLPR-RRVMTSG----GQLSILAAR 358 Query: 1911 GEDSGEYTCKAINNLGQAVSSIRLNV 1936 DSG+Y C A N++G ++ +L V Sbjct: 359 ANDSGDYFCSARNHIGSTIARTQLVV 384 Score = 36.3 bits (80), Expect = 0.61 Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 5/64 (7%) Query: 945 WLK-DGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003 W K DG P+ SS + G L +++ T+ DAG Y C+A N +G+++ + L + Sbjct: 242 WSKVDGAPLMESS----YKMLGNGRLVLENTTLEDAGLYECKAINLLGESSATMRLVVTV 297 Query: 1004 KKDI 1007 + Sbjct: 298 PPSV 301 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 5/69 (7%) Query: 806 WYK-DGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864 W K DG P+ SS G L + + EDAG Y +A+N LGE+ +T + V Sbjct: 242 WSKVDGAPLMESSYKM----LGNGRLVLENTTLEDAGLYECKAINLLGESSATMRLVVTV 297 Query: 865 RSTVTADLG 873 +V+ D+G Sbjct: 298 PPSVSIDIG 306 Score = 34.7 bits (76), Expect = 1.9 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 14/159 (8%) Query: 633 VYPPPQFIV-PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691 V+ P+FI+ P KS+ A G + + P + I W ++G+SI R Sbjct: 384 VFALPRFIISPPKSLKAEVGSDVILPCKAYG-SPPPLVITWHRHGKSIPQE-------RS 435 Query: 692 GYIS--LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749 G I L ++ + DSG Y C A S +G+ + +A+ + ++ Q + Sbjct: 436 GVIDGVLRLIDVTTADSGVYVCTATS-SGIFDAQAMTRLEVLENTAASANAAPAKQDGRS 494 Query: 750 LED--YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGR 786 L + ++K + E + S++ + L D + GR Sbjct: 495 LTNSTHAKLDMKNGFEGKVSEKGKMTLKLDDKTSSKNGR 533 Score = 34.3 bits (75), Expect = 2.5 Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 9/128 (7%) Query: 2087 KIQELEKYERPKPIEEEQ--PGQRPVFLTALTS--LENLKEGDRAHFECRVEPINDPHLT 2142 K Q+ EK ER + E+ PG A+ S L + D A F C + P L Sbjct: 182 KGQKGEKGERGIGVRGEKGAPGDTLSAPNAIVSPALITINASDTAVFHCAASGVPKPVLI 241 Query: 2143 IDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202 + + ++ G L + T ED+G Y CKA N LGE+ T L V Sbjct: 242 WSKVDGAPLMESSYKM-----LGNGRLVLENTTLEDAGLYECKAINLLGESSATMRLVVT 296 Query: 2203 GHRNIILD 2210 ++ +D Sbjct: 297 VPPSVSID 304 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH-NGKPLLTGSRVKTINDFGFVI 3616 P +P+ + ++ + +A F C V + W +G PL+ S K + + G ++ Sbjct: 209 PNAIVSPALITINASDTAVFHCAASGVPKPVLI--WSKVDGAPLMESS-YKMLGN-GRLV 264 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 LE DAGLY CKA N GE++ + +L V Sbjct: 265 LE--NTTLEDAGLYECKAINLLGESSATMRLVV 295 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 5/82 (6%) Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVK 2318 TA F C V P L ++S+ + G L +++ EDAG Y K Sbjct: 225 TAVFHCAASGVPKPVLIWSKVDGAPLMESSYKM-----LGNGRLVLENTTLEDAGLYECK 279 Query: 2319 AINALGHCTSAISMTVTAKGSI 2340 AIN LG ++ + + VT S+ Sbjct: 280 AINLLGESSATMRLVVTVPPSV 301 Score = 33.5 bits (73), Expect = 4.3 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%) Query: 1738 GDPKLRVEWLR-NGVPI-EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795 G PK + W + +G P+ E+S ++ G L ++ ED+G Y C+AIN LGE+ Sbjct: 234 GVPKPVLIWSKVDGAPLMESSYKM-----LGNGRLVLENTTLEDAGLYECKAINLLGESS 288 Query: 1796 TSSTLFVQSKASLQLE 1811 + L V S+ ++ Sbjct: 289 ATMRLVVTVPPSVSID 304 Score = 33.5 bits (73), Expect = 4.3 Identities = 16/34 (47%), Positives = 23/34 (67%) Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945 ED+G Y CKAIN LG++ +++RL V S+ D Sbjct: 271 EDAGLYECKAINLLGESSATMRLVVTVPPSVSID 304 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 7/60 (11%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 G P P ++WTR L R G +S+L + D G+Y C+ARN G I Sbjct: 325 GFPLPEINWTRSAGQLPR-----RRVMTSGGQLSILAARAN--DSGDYFCSARNHIGSTI 377 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 5/72 (6%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 I TA F C V P L L+E S ++ G + + + ED G Sbjct: 220 INASDTAVFHCAASGVPKPVLIWSKVDGAPLMESSYKM-----LGNGRLVLENTTLEDAG 274 Query: 2448 VYMCRASNLLGE 2459 +Y C+A NLLGE Sbjct: 275 LYECKAINLLGE 286 Score = 32.7 bits (71), Expect = 7.5 Identities = 12/25 (48%), Positives = 19/25 (76%) Query: 2710 DDSGIYTCKATNLLGEAVSTASIKI 2734 +D+G+Y CKA NLLGE+ +T + + Sbjct: 271 EDAGLYECKAINLLGESSATMRLVV 295 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 8/101 (7%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP + + EG + + G P +I W ++ + TS G +S Sbjct: 298 PPSVSIDIGPTYVQEGDNVMLP-KCHVTGFPLPEINWTRSAGQLPRRRVMTS---GGQLS 353 Query: 696 LDMLSLNIQDSGEYTCRAVSATG--VAETKAVLHVTPRATI 734 + L+ DSG+Y C A + G +A T+ V+ PR I Sbjct: 354 I--LAARANDSGDYFCSARNHIGSTIARTQLVVFALPRFII 392 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 7/93 (7%) Query: 3817 SDAPKEEPIVSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875 S + + +V P+FI + KS E V C+ P L I W+R+GK +P Sbjct: 375 STIARTQLVVFALPRFIISPPKSLKAEVGSDVILPCKAYGSPPP-LVITWHRHGKSIPQ- 432 Query: 3876 HRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908 R + + L ++ V DSG Y+C A + Sbjct: 433 ERSGVIDGV----LRLIDVTTADSGVYVCTATS 461 >SB_8388| Best HMM Match : ig (HMM E-Value=8.80001e-41) Length = 666 Score = 74.5 bits (175), Expect = 2e-12 Identities = 87/344 (25%), Positives = 138/344 (40%), Gaps = 33/344 (9%) Query: 140 DEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTE 199 DEG YTC A N G AI + + +T+ + +E Sbjct: 353 DEGSYTCFASNAGGTAIAVTRLVVKVPVPVLIQRDDGTLTVKTGDTIVLRCL------SE 406 Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS 259 S +Q Y NG + D K+ Y +R S ++ T R VG D T ++ Sbjct: 407 NSSPSQVTWYKNGRVLGNQGDAKL----YLTIR--SREDAGTYRCVGR-DGDRRTSKTKT 459 Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319 + PP I Q+G D Q Q+SG P+P V W K+GQ+L + + +T Sbjct: 460 IIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVR---MTVDV 516 Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRET 379 + TL +R + SDSG + + +++ + E V D+R T ++ Sbjct: 517 NNTLTIRQAESSDSGR-----DLQSRVLLSHTQIQWYKGRELVVPDRR--IATSSRGHLV 569 Query: 380 EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNH 438 I+ S+ + V + ++ F V G P P+VTWF N ++ DD + Sbjct: 570 INAIQQSDTG---YYTCVAVNTAGSDSVSVSFS--VQGNPKPKVTWFKNGYRVPLDDIKY 624 Query: 439 KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 K ++ L I + D+G+ TC A N G + L V Sbjct: 625 K----QTSADTLEIAGLVPQDTGIYTCRAENARGHDTWNITLVV 664 Score = 63.3 bits (147), Expect = 5e-09 Identities = 90/360 (25%), Positives = 128/360 (35%), Gaps = 58/360 (16%) Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529 IR D + A N GGTA LVV+ VP + V +G Sbjct: 346 IRVTTDRDEGSYTCFASNAGGTAIAVTRLVVKVP--------VPVLIQRDDGTLTVKTGD 397 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589 + L + P V W KNG+ +L G L + +D+G Y CV Sbjct: 398 TIVLRCLSENSSPSQVTWYKNGR---------VLGNQGDAKLYLTIRSREDAGTYRCVGR 448 Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649 + G+ R K +T N PP II K +G+ I+ +C++ G Sbjct: 449 D--GDRRTS--------------KTKTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGF 492 Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTAD-EYTLRISEAFPEDEG-DYKCVAYNS------ 4700 P PTVQW K G +L Q+ T D TL I +A D G D + S Sbjct: 493 PKPTVQWTKDGQQLTS-----QVRMTVDVNNTLTIRQAESSDSGRDLQSRVLLSHTQIQW 547 Query: 4701 -AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE--------GQPAQFKTQITSKIKPT 4751 GR V ++ + + D Y + KP Sbjct: 548 YKGRELVVPDRRIATSSRGHLVINAIQQSDTGYYTCVAVNTAGSDSVSVSFSVQGNPKPK 607 Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 + W + G +P D + + L I +DTG +TCRA A G + LVV+ Sbjct: 608 VTWFKNGYRVP--LDDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARGHDTWNITLVVQ 665 Score = 52.0 bits (119), Expect = 1e-05 Identities = 64/281 (22%), Positives = 110/281 (39%), Gaps = 37/281 (13%) Query: 4511 IVPPSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569 ++P S ++A + V V G V L V P V W K + P + ++ + + T+ Sbjct: 286 VLPDSPKVSADSLVEVLRGSPVTLTCMVDSVTPFRVQWTKGRDALGP-VLTRVGQVNVTH 344 Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629 ++ + +D G Y C A N+ G A VV +P P +I+ Sbjct: 345 SIRVTT--DRDEGSYTCFASNAGGTAIAVTRLVVKVPV---------------PVLIQRD 387 Query: 4630 KDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688 + V G I C V WYK +++ + L ++ E Sbjct: 388 DGTLTVKTGDTIVLRCLSENSSPSQVTWYKNGRVL---------GNQGDAKLYLTIRSRE 438 Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748 D G Y+CV + R + + V +P + T ++ +G+ Q Q++ Sbjct: 439 DAGTYRCVGRDGDRRTSKTKTIIVNEPPV---IIVDTSTKNF--QQGEDIQCACQVSGFP 493 Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789 KPT+QW ++G + T +M + NN L I D+G Sbjct: 494 KPTVQWTKDGQQL--TSQVRMTVDVNN-TLTIRQAESSDSG 531 Score = 46.4 bits (105), Expect = 6e-04 Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 9/122 (7%) Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER 496 N ++L N+ G+ L +T + D+G CV R+ T+ + V E P + Sbjct: 418 NGRVLGNQ-GDAKLYLTIRSREDAGTYRCVGRDGDRRTSKTKTIIVNE-----PPVIIVD 471 Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556 ST N ++GE + + G P P + W KDG + + + + +TL I +A++S Sbjct: 472 TSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMTVDVN---NTLTIRQAESS 528 Query: 557 DA 558 D+ Sbjct: 529 DS 530 Score = 44.0 bits (99), Expect = 0.003 Identities = 54/207 (26%), Positives = 91/207 (43%), Gaps = 23/207 (11%) Query: 939 STLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSAN 998 S +V W K+GR + + LTI+S DAG Y C + G TS Sbjct: 409 SPSQVTWYKNGRVLGNQGDAKLY-------LTIRSR--EDAGTYRCVGRD--GDRRTSKT 457 Query: 999 LTIVTKKD--IIAESQHPGGL--EKIQYLEDASRYSKRTEEEVK----ITQKPRFLGPLK 1050 TI+ + II ++ E IQ S + K T + K +T + R + Sbjct: 458 KTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMTVDVN 517 Query: 1051 GTNKIVEGQSAHFEARVEPQSDLTMT-VEWYFNGKQITSANRIQTYHDFGYVALDIASVR 1109 T I + +S+ ++ + L+ T ++WY + + RI T G++ ++ +++ Sbjct: 518 NTLTIRQAESSDSGRDLQSRVLLSHTQIQWYKGRELVVPDRRIAT-SSRGHLVIN--AIQ 574 Query: 1110 AEDSGVYTVVARNAAGEAQLSASMTVE 1136 D+G YT VA N AG +S S +V+ Sbjct: 575 QSDTGYYTCVAVNTAGSDSVSVSFSVQ 601 Score = 43.6 bits (98), Expect = 0.004 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 6/68 (8%) Query: 1738 GDPKLRVEWLRNG--VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795 G+PK +V W +NG VP++ T D L + + P+D+G YTCRA N G Sbjct: 602 GNPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDT 657 Query: 1796 TSSTLFVQ 1803 + TL VQ Sbjct: 658 WNITLVVQ 665 Score = 41.5 bits (93), Expect = 0.016 Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 4/58 (6%) Query: 2802 DPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSAT 2858 +P K+ WF N +P +YK T S +L+I +D+GIYTC+A N++G T Sbjct: 603 NPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAENARGHDT 657 Score = 41.1 bits (92), Expect = 0.021 Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 16/121 (13%) Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGE 506 H++ +T T D G TC A N G RL V +V P ++R TL V+ G+ Sbjct: 344 HSIRVT--TDRDEGSYTCFASNAGGTAIAVTRLVV----KVPVPVLIQRDDGTLTVKTGD 397 Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566 +VL + + ++TW K+G R+ + G + L + DA Y+C + Sbjct: 398 TIVLRCLSENSSPSQVTWYKNG---------RVLGNQGDAKLYLTIRSREDAGTYRCVGR 448 Query: 567 N 567 + Sbjct: 449 D 449 Score = 41.1 bits (92), Expect = 0.021 Identities = 44/195 (22%), Positives = 77/195 (39%), Gaps = 22/195 (11%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P + ++ +G+ + C+V+G P P V W + +Q+ + VN + L Sbjct: 466 PVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMTVDVNNT----LT 521 Query: 452 ITNVTLSDSG------VV---TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST--- 499 I SDSG V+ T + K E R + +++ T Sbjct: 522 IRQAESSDSGRDLQSRVLLSHTQIQWYKGRELVVPDRRIATSSRGHLVINAIQQSDTGYY 581 Query: 500 ----LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555 +N + V ++ G P P++TW K+G +P +++ + A TL+I Sbjct: 582 TCVAVNTAGSDSVSVSFSVQGNPKPKVTWFKNGYR-VPLDDIK-YKQTSADTLEIAGLVP 639 Query: 556 SDAAWYQCTAQNVAG 570 D Y C A+N G Sbjct: 640 QDTGIYTCRAENARG 654 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/57 (43%), Positives = 30/57 (52%), Gaps = 12/57 (21%) Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYV-----ALDIIDLIAEDSGIYTCRAVNLVGTD 1528 KV WFKNG V P+ D Y L+I L+ +D+GIYTCRA N G D Sbjct: 607 KVTWFKNGYRV-------PLDDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARGHD 656 Score = 39.9 bits (89), Expect = 0.049 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 2/70 (2%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDI 4169 PPV + ++GE + C+V+G PKP V W +G + S+ ++T D I Sbjct: 465 PPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLT--SQVRMTVDVNNTLTI 522 Query: 4170 PKTRQYDTGK 4179 + D+G+ Sbjct: 523 RQAESSDSGR 532 Score = 39.5 bits (88), Expect = 0.065 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 4/57 (7%) Query: 2938 KNDPDLKIEWYFNG-KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 + +P K+ W+ NG +V ++K TS TL++ + +D+GIYTC+A N RG Sbjct: 601 QGNPKPKVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTCRAENARG 654 Score = 38.3 bits (85), Expect = 0.15 Identities = 48/212 (22%), Positives = 86/212 (40%), Gaps = 17/212 (8%) Query: 3444 LTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGE 3503 L+ P+ +V WY NG+ L G++ G L ++ ED+G Y C + Sbjct: 404 LSENSSPS-QVTWYKNGRVL--GNQ-------GDAKLYLTIRSREDAGTYRCVGRDGDRR 453 Query: 3504 AVTTASMKVQGKRNIILESQLPKGMEGT-IDKIAALEGY-SGTVDTLTPEAESGNPPEFT 3561 T ++ V II+++ +G I + G+ TV + + T Sbjct: 454 TSKTKTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMT 513 Query: 3562 TTPSDLILSENSSAHFECRLIP--VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEI 3619 ++ + + + R + V S +++W+ G+ L+ R + G ++ I Sbjct: 514 VDVNNTLTIRQAESSDSGRDLQSRVLLSHTQIQWY-KGRELVVPDRRIATSSRGHLV--I 570 Query: 3620 GGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651 + Q D G YTC A N G +VS V+G Sbjct: 571 NAIQQSDTGYYTCVAVNTAGSDSVSVSFSVQG 602 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 2671 DPNLKIEWFKNGVTLTTG-ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724 +P K+ WFKNG + + K T TL I L D+GIYTC+A N G Sbjct: 603 NPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAENARG 654 Score = 37.5 bits (83), Expect = 0.26 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 3/58 (5%) Query: 1474 SNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531 S+ +++W+K G+ + + R G++ ++ I D+G YTC AVN G+D VS Sbjct: 541 SHTQIQWYK-GRELVVPDRRIATSSRGHLVINAIQ--QSDTGYYTCVAVNTAGSDSVS 595 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 6/63 (9%) Query: 3590 RVEWFHNGK--PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647 +V WF NG PL +T D LEI G+ +D G+YTC+A N G T + L Sbjct: 607 KVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTWNITL 662 Query: 3648 QVK 3650 V+ Sbjct: 663 VVQ 665 Score = 36.7 bits (81), Expect = 0.46 Identities = 36/162 (22%), Positives = 60/162 (37%), Gaps = 19/162 (11%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V G + +C + VQW KG + P ++ + +++R++ DEG Y Sbjct: 301 VLRGSPVTLTCMVDSVTPFRVQWTKGRDALGPV-LTRVGQVNVTHSIRVTT--DRDEGSY 357 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD--IVVYEGQPAQFKTQITSKIKPT 4751 C A N+ G +L V P +P L D + V G + + Sbjct: 358 TCFASNAGGTAIAVTRLVVKVP-----VPVLIQRDDGTLTVKTGDTIVLRCLSENSSPSQ 412 Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793 + W + G ++ D A L + ED GT+ C Sbjct: 413 VTWYKNGRVLGNQGD---------AKLYLTIRSREDAGTYRC 445 Score = 36.7 bits (81), Expect = 0.46 Identities = 45/246 (18%), Positives = 90/246 (36%), Gaps = 17/246 (6%) Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884 +V P + Q T+ G R + ++ WY+NG++L + Sbjct: 375 VVKVPVPVLIQRDDGTLTVKTGDTIVLRCLSENSSPSQVTWYKNGRVLGN---------Q 425 Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944 G L + ED+G Y C D +K P +I+ + + ++ E + Sbjct: 426 GDAKLYLTIRSREDAGTYRCVG-RDGDRRTSKTKTIIVNEPPVIIVDTSTKNFQQGEDI- 483 Query: 3945 QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQL-APVGDP 4003 Q + + D + + R + + ++ + E++ L + V Sbjct: 484 QCACQVSGFPKPTVQWTKDGQQLTSQV--RMTVDVNNTLTIRQAESSDSGRDLQSRVLLS 541 Query: 4004 NMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063 + +++W+ G+ L+ +R G++ +N + D+G Y C A N G D Sbjct: 542 HTQIQWY-KGRELVVPDRRIATSSRGHLVINA--IQQSDTGYYTCVAVNTAGSDSVSVSF 598 Query: 4064 KTTGKP 4069 G P Sbjct: 599 SVQGNP 604 Score = 35.9 bits (79), Expect = 0.80 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718 G+P K+ W KNG + + +L++ L QD+G YTCRA +A G Sbjct: 602 GNPKPKVTWFKNGYRVPLDD--IKYKQTSADTLEIAGLVPQDTGIYTCRAENARG 654 Score = 35.1 bits (77), Expect = 1.4 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 13/108 (12%) Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG---SRVHTLN 3748 P+ P+ + + ++V G PV C V+ V R+ W GR A G +RV +N Sbjct: 288 PDSPKVSAD--SLVEVLRGSPVTLTCMVDSV--TPFRVQWT-KGRD-ALGPVLTRVGQVN 341 Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796 I + D RD G YTC A+N G+A ++ ++++ Sbjct: 342 VTHSIRVTTD----RDEGSYTCFASNAGGTAIAVTRLVVKVPVPVLIQ 385 Score = 34.7 bits (76), Expect = 1.9 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 8/61 (13%) Query: 95 LRGNPTPVVSWTRK--KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQY 152 ++GNP P V+W + + PL + ++Y + + D +L I + P D G YTC A N Sbjct: 600 VQGNPKPKVTWFKNGYRVPLDD-----IKYKQTSAD-TLEIAGLVPQDTGIYTCRAENAR 653 Query: 153 G 153 G Sbjct: 654 G 654 Score = 34.7 bits (76), Expect = 1.9 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 4/63 (6%) Query: 3858 DPKLRIEWYRNGKLLPSGH-RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTK 3916 +PK ++ W++NG +P +Y+ +L+I + +D+G Y CRA N G D Sbjct: 603 NPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAENARGHDTWN 659 Query: 3917 ATI 3919 T+ Sbjct: 660 ITL 662 Score = 34.3 bits (75), Expect = 2.5 Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 12/167 (7%) Query: 704 QDSGEYTCRAVSATG-VAETKAVLHVTPRATIERTS----QHPETLQYIQQLEDYSK--Y 756 +D+G Y C ++TK ++ P I TS Q E +Q Q+ + K Sbjct: 438 EDAGTYRCVGRDGDRRTSKTKTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTV 497 Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQ-EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815 Q + ++ TSQ + L Q E ++ + Q + T +++WYK GR + Sbjct: 498 QWTKDGQQLTSQVRMTVDVNNTLTIRQAESSDSGRDLQSRVLLSHT-QIQWYK-GRELVV 555 Query: 816 SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 R + + G++ +N ++ D G YT AVN G + S V Sbjct: 556 PDRRIATSSRGHLVINA--IQQSDTGYYTCVAVNTAGSDSVSVSFSV 600 Score = 34.3 bits (75), Expect = 2.5 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 2/65 (3%) Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397 G+ +V WF NG + D L++ + P+D+G+YTC+A N G + Sbjct: 602 GNPKPKVTWFKNGYRVPLDDIKYKQTSAD--TLEIAGLVPQDTGIYTCRAENARGHDTWN 659 Query: 1398 CALRV 1402 L V Sbjct: 660 ITLVV 664 Score = 33.9 bits (74), Expect = 3.2 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 3/61 (4%) Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +I+W+K + R+ ++ LV IN+++ D+G YTC A N G + S + Sbjct: 544 QIQWYKGRELVVPDRRIATSSRGHLV---INAIQQSDTGYYTCVAVNTAGSDSVSVSFSV 600 Query: 2735 E 2735 + Sbjct: 601 Q 601 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 6/67 (8%) Query: 1873 DPNMRVEWYFNG-KVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930 +P +V W+ NG +V +Y+ TS D L+I + +D+G YTC+A N G Sbjct: 603 NPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTW 658 Query: 1931 SIRLNVQ 1937 +I L VQ Sbjct: 659 NITLVVQ 665 Score = 33.5 bits (73), Expect = 4.3 Identities = 46/209 (22%), Positives = 87/209 (41%), Gaps = 21/209 (10%) Query: 2005 NDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064 N +V WY NGR + G++ G L + ED GTY C + T Sbjct: 407 NSSPSQVTWYKNGRVL--GNQ-------GDAKLYLTIRSREDAGTYRCVGRDGDRRTSKT 457 Query: 2065 SSVKVDAKSGLYLDTLDE--QRLKKIQ-ELEKYERPKP-IEEEQPGQRPVFLTALTSLEN 2120 ++ V+ + +DT + Q+ + IQ + PKP ++ + GQ+ +T N Sbjct: 458 KTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMTVDVN 517 Query: 2121 ----LKEGDRAHFECRVEP-INDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175 +++ + + ++ + H I W+ G+++ R T G++ ++ + Sbjct: 518 NTLTIRQAESSDSGRDLQSRVLLSHTQIQWY-KGRELVVPDRRIATSSRGHLVINAIQQ- 575 Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGH 2204 D+G Y C A N G + + V G+ Sbjct: 576 -SDTGYYTCVAVNTAGSDSVSVSFSVQGN 603 Score = 33.5 bits (73), Expect = 4.3 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 4/56 (7%) Query: 2536 GDPSLRFEWYINGVELKMGS-RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G+P + W+ NG + + +++ T TL+I +V D G+Y C+A N G Sbjct: 602 GNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAENARG 654 Score = 33.1 bits (72), Expect = 5.7 Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 3/61 (4%) Query: 1877 RVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 +++WY +++ R TS+ L I + D+G YTC A+N G S+ +V Sbjct: 544 QIQWYKGRELVVPDRRIATSSR---GHLVINAIQQSDTGYYTCVAVNTAGSDSVSVSFSV 600 Query: 1937 Q 1937 Q Sbjct: 601 Q 601 Score = 33.1 bits (72), Expect = 5.7 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 4/51 (7%) Query: 1610 KVEWYHNNKPLKSGS-RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 KV W+ N + ++ +T+ L+I +P+D+G YTCRA NA G Sbjct: 607 KVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTCRAENARG 654 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 12/62 (19%) Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV-----AMNFGWVYPEDSGEYLCRATNLYG 4055 G+P KV WF NG + P+ D Y + + P+D+G Y CRA N G Sbjct: 602 GNPKPKVTWFKNGYRV-------PLDDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARG 654 Query: 4056 MD 4057 D Sbjct: 655 HD 656 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 6/67 (8%) Query: 3449 DPNLKVEWYWNGKSLKAGS-RFR-TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVT 3506 +P KV W+ NG + +++ T D LEI+ P+D+G Y CRA N G Sbjct: 603 NPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTW 658 Query: 3507 TASMKVQ 3513 ++ VQ Sbjct: 659 NITLVVQ 665 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 3178 DPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235 +P K+ W+ NG P+ +T +D L+IA D+G Y CRA N G D Sbjct: 603 NPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTW 658 Query: 3236 RATI 3239 T+ Sbjct: 659 NITL 662 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 3/50 (6%) Query: 2541 RFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 + +WY G EL + R T G + IN++ +D G Y C A+N AG Sbjct: 544 QIQWY-KGRELVVPDRRIATSSRGHLV--INAIQQSDTGYYTCVAVNTAG 590 >SB_51089| Best HMM Match : I-set (HMM E-Value=1.4e-38) Length = 1334 Score = 74.5 bits (175), Expect = 2e-12 Identities = 66/200 (33%), Positives = 88/200 (44%), Gaps = 20/200 (10%) Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441 R+EI +AP R + G+ DC G P PEV W +N I K+L Sbjct: 1064 RVEILVDLIAPVIQTKSLPRTLVFGQTLLLDCEAKGSPQPEVKWMLNGNDI---IFGKVL 1120 Query: 442 VNESGNHALMITNVTLSDS--GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499 N S L + V D+ G TC A N+ ++ + E Q++ P + R ST Sbjct: 1121 ANGS----LKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTP--LTR-ST 1173 Query: 500 LNVREGEPVVLNARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558 +R G+ VL A G P PRI W +KDG IP PE RI ++ L IP A + DA Sbjct: 1174 AVLR-GKSAVLTCYATGDPMPRIAWSKKDGT--IP-PE-RIRSNN--HVLLIPHATSRDA 1226 Query: 559 AWYQCTAQNVAGSTATRARL 578 Y C A N + L Sbjct: 1227 GTYSCIATNYIKEVTSETNL 1246 Score = 58.8 bits (136), Expect = 1e-07 Identities = 48/186 (25%), Positives = 76/186 (40%), Gaps = 26/186 (13%) Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 GQ + LD + G+ +V W+ NG + I K+L +G+ + +E G Y C Sbjct: 1088 GQTLLLDCEAKGSPQPEVKWMLNGNDI---IFGKVLA-NGSLKVEKVENDDNFEGTYTCR 1143 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL-KDKIVAEGQAIEFSCKI 4646 A N AR + + + P+I+ PL + V G++ +C Sbjct: 1144 ASNRVSTARSSTQVTI----------------HEGPQILTPLTRSTAVLRGKSAVLTCYA 1187 Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 G P+P + W K D I P + ++ + L I A D G Y C+A N VT Sbjct: 1188 TGDPMPRIAWSKKDGTIPPERI-----RSNNHVLLIPHATSRDAGTYSCIATNYIKEVTS 1242 Query: 4707 AAKLKV 4712 L + Sbjct: 1243 ETNLTI 1248 Score = 56.8 bits (131), Expect = 4e-07 Identities = 49/181 (27%), Positives = 75/181 (41%), Gaps = 21/181 (11%) Query: 4637 GQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKYFQMSRTADEYTLRISEAFPED--EGDY 4693 GQ + C+ G P P V+W G+ +I + +L++ + +D EG Y Sbjct: 1088 GQTLLLDCEAKGSPQPEVKWMLNGNDII-------FGKVLANGSLKVEKVENDDNFEGTY 1140 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTI 4752 C A N + ++ + + Q LTPL R V G+ A T P I Sbjct: 1141 TCRASNRVSTARSSTQVTIHEGPQI-----LTPLTRSTAVLRGKSAVLTCYATGDPMPRI 1195 Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812 W ++ IP + I NN VLLI + D GT++C AT +V + L + Sbjct: 1196 AWSKKDGTIPP----ERIRS-NNHVLLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIG 1250 Query: 4813 K 4813 K Sbjct: 1251 K 1251 Score = 46.8 bits (106), Expect = 4e-04 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 10/119 (8%) Query: 367 RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426 R+ T + T+ I + L P + + V GK C TG P P + W Sbjct: 1143 RASNRVSTARSSTQVTIHEGPQILTP----LTRSTAVLRGKSAVLTCYATGDPMPRIAWS 1198 Query: 427 INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485 D I + +I S NH L+I + T D+G +C+A N E + L +I K Sbjct: 1199 KKDGTIPPE---RI---RSNNHVLLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGK 1251 Score = 42.3 bits (95), Expect = 0.009 Identities = 49/192 (25%), Positives = 78/192 (40%), Gaps = 19/192 (9%) Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135 G ++W NG I V A G + +E + GTY+CRA+N+ A S Sbjct: 1099 GSPQPEVKWMLNGNDIIFGK----VLANGSLKVEKVENDDNFEGTYTCRASNRVSTARSS 1154 Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195 ++ + + P+ T + + G+SA C DP +I W + Sbjct: 1155 TQV-----TIHEGPQILTPLTRSTAVLRGKSAVLTC--YATGDPMPRIAWSKKDGTI-PP 1206 Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK---GGVYLESL 3252 RI++ + VL I + + D+G Y C A N E + + GK GG + Sbjct: 1207 ERIRSNNH----VLLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKMEGGGSCSVPV 1262 Query: 3253 QPDSLAKIRELE 3264 + SL + ELE Sbjct: 1263 RMSSLPEHGELE 1274 Score = 41.1 bits (92), Expect = 0.021 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 6/121 (4%) Query: 1165 PMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224 P ++E + +Q S P + G+ + L+C E G P V+W NG + G Sbjct: 1061 PCLRVEILVDLIAPVIQTKSLPRTLVFGQTLLLDC--EAKGSPQPEVKWMLNGNDIIFGK 1118 Query: 1225 RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQA 1284 G + ++ + G YT RA N + +A +S V + E I+T A Sbjct: 1119 VLAN----GSLKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTPLTRSTA 1174 Query: 1285 I 1285 + Sbjct: 1175 V 1175 Score = 41.1 bits (92), Expect = 0.021 Identities = 46/196 (23%), Positives = 72/196 (36%), Gaps = 23/196 (11%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 P I TK + VF + + E G P P +KW + N D L Sbjct: 1074 PVIQTKSLPRTLVFG-QTLLLDCEAKGSPQPEVKW------MLNGNDIIFGKVLANGSLK 1126 Query: 4470 IRQVFVEDS--AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 + +V +D+ + A NR TA+ S + + E P T ++ V Sbjct: 1127 VEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEG---------PQILTPLTRSTAVLR 1177 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 G+ L TG + W K + P+ +I + LLI A +D+G Y C+ Sbjct: 1178 GKSAVLTCYATGDPMPRIAWSKKDGTIPPE---RI--RSNNHVLLIPHATSRDAGTYSCI 1232 Query: 4588 AINSAGEARCDAECVV 4603 A N E + + Sbjct: 1233 ATNYIKEVTSETNLTI 1248 Score = 39.5 bits (88), Expect = 0.065 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 13/99 (13%) Query: 2641 APIFTTHLKSYDK-LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 AP+ T KS + LV GQ + L+ E + P +++W NG + G L + Sbjct: 1073 APVIQT--KSLPRTLVFGQTLLLDC--EAKGSPQPEVKWMLNGNDIIFGKVLANG----- 1123 Query: 2700 VTLSINSLRNDDS--GIYTCKATNLLGEAVSTASIKIED 2736 +L + + NDD+ G YTC+A+N + A S+ + I + Sbjct: 1124 -SLKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHE 1161 Score = 39.1 bits (87), Expect = 0.086 Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 9/140 (6%) Query: 1802 VQSKASLQLES-QHESALQKIQQLEDSSRYQR-REDVEVAVNQAPRFITQLNGPTKLSEG 1859 V + SL++E +++ + S+R R +V +++ P+ +T L T + G Sbjct: 1119 VLANGSLKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTPLTRSTAVLRG 1178 Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919 +SA C DP R+ W + R R++N L I D+G Y+C Sbjct: 1179 KSAVLTCYAT--GDPMPRIAWSKKDGTIPP-ERIRSNNH----VLLIPHATSRDAGTYSC 1231 Query: 1920 KAINNLGQAVSSIRLNVQSK 1939 A N + + S L + K Sbjct: 1232 IATNYIKEVTSETNLTIIGK 1251 Score = 37.1 bits (82), Expect = 0.35 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 7/98 (7%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P+ TP+ ++ G A GD R+ W K + RI + + Sbjct: 1163 PQILTPLTRSTAVLRGKSAVLTCYAT--GDPMPRIAWSKKDGTIPPE-RIRSNNH----V 1215 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006 L I T DAG Y+C A N I + T+ NLTI+ K + Sbjct: 1216 LLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKME 1253 Score = 35.9 bits (79), Expect = 0.80 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 10/119 (8%) Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895 VE+ V+ I + P L GQ+ +C + P P V+W NG + G Sbjct: 1065 VEILVDLIAPVIQTKSLPRTLVFGQTLLLDCEAKGSPQPE--VKWMLNGNDIIFGKVLAN 1122 Query: 1896 SNDFGFAALDILTVYGEDS--GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952 + L + V +D+ G YTC+A N + A SS ++ + I+ +A+ Sbjct: 1123 GS------LKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTPLTRSTAV 1175 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 6/79 (7%) Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982 LV GQ L L+ E K P +++W NG + G K+ ++ G + ++ V+ + G Sbjct: 1085 LVFGQTLLLD--CEAKGSPQPEVKWMLNGNDIIFG---KVLAN-GSLKVEKVENDDNFEG 1138 Query: 2983 IYTCKAYNKRGEAFTSSTV 3001 YTC+A N+ A +S+ V Sbjct: 1139 TYTCRASNRVSTARSSTQV 1157 Score = 34.7 bits (76), Expect = 1.9 Identities = 14/34 (41%), Positives = 19/34 (55%) Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154 T+ G+ C G P+P V W+LNGN I+ G Sbjct: 1084 TLVFGQTLLLDCEAKGSPQPEVKWMLNGNDIIFG 1117 Score = 34.3 bits (75), Expect = 2.5 Identities = 39/132 (29%), Positives = 54/132 (40%), Gaps = 14/132 (10%) Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288 ST++ + E P+ +T L +T V GK+A C DP RI + + Sbjct: 1154 STQVTIHEG----PQILTPLTRSTAVLRGKSAVLTCYA--TGDPMPRIAWSKKDGTIPPE 1207 Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK---GSIISESQ 2345 R +V L I H DAG YS A N + TS ++T+ K G S Sbjct: 1208 -RIRSN---NHVLL-IPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKMEGGGSCSVPV 1262 Query: 2346 RPEGLEKIRELE 2357 R L + ELE Sbjct: 1263 RMSSLPEHGELE 1274 Score = 34.3 bits (75), Expect = 2.5 Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 7/98 (7%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P + PL+ V GK+ L C GDP R+ W ++ R ++ Sbjct: 1163 PQILTPLTRSTAVLRGKSAVLTCYAT--GDPMPRIAWSKKDGTIPP-ERIRSNNH----V 1215 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274 L I HATS D G Y+ A N++ + + +I + + Sbjct: 1216 LLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKME 1253 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 6/73 (8%) Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVS--ATG 718 E G P +++W+ NG I F + G + ++ + + G YTCRA + +T Sbjct: 1096 EAKGSPQPEVKWMLNGNDI----IFGKVLANGSLKVEKVENDDNFEGTYTCRASNRVSTA 1151 Query: 719 VAETKAVLHVTPR 731 + T+ +H P+ Sbjct: 1152 RSSTQVTIHEGPQ 1164 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/128 (21%), Positives = 47/128 (36%), Gaps = 9/128 (7%) Query: 2334 VTAKGSI-ISESQRPEGLEKIRELESAEPFKRPEIPEPVT-RQRPVFTQPLQNIDNIQEG 2391 V A GS+ + + + + E ++ VT + P PL + G Sbjct: 1119 VLANGSLKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTPLTRSTAVLRG 1178 Query: 2392 QTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMC 2451 ++A C GDP ++ W + + I + H + I H D G Y C Sbjct: 1179 KSAVLTC--YATGDPMPRIAWSKKDGTIPPERIRSNNH-----VLLIPHATSRDAGTYSC 1231 Query: 2452 RASNLLGE 2459 A+N + E Sbjct: 1232 IATNYIKE 1239 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 5/78 (6%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 P + R++ + G A +G+P PR+ W K + E I ++NH L Sbjct: 1163 PQILTPLTRSTAVLRGKSAVLTCYATGDPMPRIAWSKKDGTI----PPERIRSNNHVLL- 1217 Query: 325 VRNTQKSDSGHYTLLAEN 342 + + D+G Y+ +A N Sbjct: 1218 IPHATSRDAGTYSCIATN 1235 Score = 32.7 bits (71), Expect = 7.5 Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 8/133 (6%) Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339 E P+ +T + T ++ G+SA DP ++ W +P R R+ + Sbjct: 1161 EGPQILTPLTRSTAVLRGKSAVLTC--YATGDPMPRIAWSKKDGTIPP-ERIRSNNH--- 1214 Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQT 3399 +L I + ++G Y C+ATN + +++ NL K +P M L + Sbjct: 1215 -VLLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKMEGGGSCSVPVRM-SSLPEHGE 1272 Query: 3400 LEDSMVRRKDTSV 3412 LE KDT + Sbjct: 1273 LEPGSHTAKDTDI 1285 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 6/93 (6%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 GDP RI W R+ + N L I + +RDAG Y+C ATN T+ Sbjct: 1189 GDPMPRIAWSKKDGTIPP-ERIRSNNH----VLLIPHATSRDAGTYSCIATNYIKEVTSE 1243 Query: 3783 AKITCSAKRDIVLESQLPQGMSG-EKIKELERG 3814 +T K + +P MS + ELE G Sbjct: 1244 TNLTIIGKMEGGGSCSVPVRMSSLPEHGELEPG 1276 >SB_31697| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 518 Score = 74.1 bits (174), Expect = 2e-12 Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 1/116 (0%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ-MSRTADEYTL 4680 PP + LKD + EG A F C+I G P P V+WY+ +L+K K + D L Sbjct: 26 PPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKL 85 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736 I+E D G+YK VA N G+V+ +AKL + P +D+ A DI E + Sbjct: 86 IITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPSDDESASDAESDISEEESE 141 Score = 72.9 bits (171), Expect = 6e-12 Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 2/121 (1%) Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN-H 320 P PP QK ++ K+ EG+ A+F+ Q++GNP P V W++NG+ L + + N + Sbjct: 23 PKGPPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDN 82 Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380 L + + +D+G Y ++AEN +G + S L + P S + S +D + E+E Sbjct: 83 CKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPS-DDESASDAESDISEEESE 141 Query: 381 E 381 + Sbjct: 142 D 142 Score = 68.9 bits (161), Expect = 9e-11 Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 1/97 (1%) Query: 4407 PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTFSTK 4465 P PP+F +K++ C++ E ARFE + G P P ++WYR +K ++ + Sbjct: 23 PKGPPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDN 82 Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502 LII + D+ + VAENR G CSA L++ + Sbjct: 83 CKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIIND 119 Score = 68.9 bits (161), Expect = 9e-11 Identities = 32/88 (36%), Positives = 49/88 (55%), Gaps = 1/88 (1%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP+F+Q K+ + +G A+FE ++ GNP P V W R L EC + + Y+E + Sbjct: 26 PPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDE-NDNCK 84 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS 158 L+I + D GEY A N++G+ CS Sbjct: 85 LIITEGKHADAGEYKVVAENRHGKVSCS 112 Score = 62.1 bits (144), Expect = 1e-08 Identities = 29/89 (32%), Positives = 48/89 (53%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P F + +D + EG RF+C++TG P PEV W+ N +++ L +E+ N L+ Sbjct: 27 PVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKLI 86 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRL 480 IT +D+G VA N+ G+ + +L Sbjct: 87 ITEGKHADAGEYKVVAENRHGKVSCSAKL 115 Score = 56.8 bits (131), Expect = 4e-07 Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 1/129 (0%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL-EEDGTYTL 4571 PP F ++ + G R + ++TG +V W +NG+ ++ + L +E+ L Sbjct: 26 PPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKL 85 Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631 +I E D+G+Y+ VA N G+ C A+ +++ P D ++ E E Sbjct: 86 IITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPSDDESASDAESDISEEESEDEDK 145 Query: 4632 KIVAEGQAI 4640 +V + AI Sbjct: 146 DVVLKSDAI 154 Score = 56.4 bits (130), Expect = 5e-07 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYE 4785 L+D + EG A+F+ QIT +P ++W R G L+ E ++ E +N L+I Sbjct: 33 LKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKLIITEGKH 92 Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810 D G + A G+V SAKL++ Sbjct: 93 ADAGEYKVVAENRHGKVSCSAKLII 117 Score = 54.8 bits (126), Expect = 2e-06 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 7/149 (4%) Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760 ++ D+V PVF +KD ++ E AA FE ++ G+P+ VEW RNG ++ +LT Sbjct: 17 NSTDDVPKGPPVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLT 74 Query: 1761 TMHDFG-YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819 ++D L + D+G Y A N G+ S+ L + + S ESA Sbjct: 75 FLYDENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIIND----PVPSDDESASD 130 Query: 1820 KIQQLEDSSRYQRREDVEVAVNQAPRFIT 1848 + + +DV + + ++ T Sbjct: 131 AESDISEEESEDEDKDVVLKSDAITKYYT 159 Score = 49.6 bits (113), Expect = 6e-05 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 14/129 (10%) Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG-FV 3887 PP F ++K + E RFEC++ +P+ +EWYRNG+LL + +YD Sbjct: 26 PPVFKQKLKDCKIIEGSAARFECQITGNPEPE--VEWYRNGELLKECKQLTFLYDENDNC 83 Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQME 3947 L I D+GEY A N G+ +SC +I+ + VP E+ + E Sbjct: 84 KLIITEGKHADAGEYKVVAENRHGK------VSCS--AKLIINDPVP---SDDESASDAE 132 Query: 3948 ATIKKYTSE 3956 + I + SE Sbjct: 133 SDISEEESE 141 Score = 49.2 bits (112), Expect = 8e-05 Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 4/92 (4%) Query: 2369 EPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428 + V + PVF Q L++ I EG A F+C++ G+P +VEW+RN +L+++ ++T Sbjct: 20 DDVPKGPPVFKQKLKDC-KIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFL 76 Query: 2429 HDFG-YVSMTISHVRDEDEGVYMCRASNLLGE 2459 +D + I+ + D G Y A N G+ Sbjct: 77 YDENDNCKLIITEGKHADAGEYKVVAENRHGK 108 Score = 48.8 bits (111), Expect = 1e-04 Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 6/133 (4%) Query: 1170 EEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229 +++ K PVF Q L + + EG EC++ G+P VEW+ NG + + Sbjct: 20 DDVPKGPPVFKQKLKDCK-IIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFL 76 Query: 1230 YDFG-FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQI 1288 YD L I AD GEY V A N G SA ++I + +D ++ E Sbjct: 77 YDENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSA--KLIINDPVPSDDESASDAESD 134 Query: 1289 QLLEDAARRTKQV 1301 E++ K V Sbjct: 135 ISEEESEDEDKDV 147 Score = 48.0 bits (109), Expect = 2e-04 Identities = 43/143 (30%), Positives = 67/143 (46%), Gaps = 16/143 (11%) Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604 V T + G PP F D + E S+A FEC++ + VEW+ NG+ L Sbjct: 15 VGNSTDDVPKG-PPVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECK 71 Query: 3605 RVKTI---NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL 3661 ++ + ND +I+ G DAG Y A NRHG+ + S KL II +P + Sbjct: 72 QLTFLYDENDNCKLIITEGK--HADAGEYKVVAENRHGKVSCSAKL-------IINDP-V 121 Query: 3662 PSHFKSGTESIQKLEETLHKREE 3684 PS +S +++ + E + E+ Sbjct: 122 PSDDESASDAESDISEEESEDED 144 Score = 46.8 bits (106), Expect = 4e-04 Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 4/103 (3%) Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096 G DD PP F KD I EG A +E + TG+ +EW+ NG+ ++ + Sbjct: 16 GNSTDDVPKGPPVFKQKLKDC-KIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQ 72 Query: 3097 IRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138 + +Y L I K D+G Y A N+ G+ S KL Sbjct: 73 LTFLYDENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKL 115 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 4/93 (4%) Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG-I 3339 PP F +++D K++EG +A FE ++ +P+ +VEW+ NG+ L + +D Sbjct: 26 PPVFKQKLKDC-KIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFLYDENDN 82 Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 L I ++GEY+ VA N+ G+ S A L Sbjct: 83 CKLIITEGKHADAGEYKVVAENRHGKVSCSAKL 115 Score = 46.0 bits (104), Expect = 8e-04 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 4/104 (3%) Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ-TYHDFGYV 1101 P F LK KI+EG +A FE ++ + VEWY NG+ + ++ Y + Sbjct: 27 PVFKQKLKDC-KIIEGSAARFECQITGNPE--PEVEWYRNGELLKECKQLTFLYDENDNC 83 Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSS 1145 L I + D+G Y VVA N G+ SA + + D S Sbjct: 84 KLIITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPSDDES 127 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 5/99 (5%) Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296 PK PP F +L+ + EG A FECQ+ +P +E+Y NG+ L+ + +D Sbjct: 23 PK-GPPVFKQKLKDCK-IIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFLYD 78 Query: 2297 FG-YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 L I DAGEY V A N G + + + + Sbjct: 79 ENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKLII 117 Score = 45.6 bits (103), Expect = 0.001 Identities = 42/178 (23%), Positives = 77/178 (43%), Gaps = 12/178 (6%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY-EFDYVA 1369 P F + L + + +EG+ EC++ G+ VEW+ NG+ +K + Y E D Sbjct: 27 PVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFLYDENDNCK 84 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSR 1429 L + D+G Y A N+ G+ SC+ + LI+ PS E E Sbjct: 85 LIITEGKHADAGEYKVVAENRHGK--VSCSAK------LIINDPVPSDDESASDAESDIS 136 Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECK-LEPVTDSNLKVEWFKNGQP 1486 ++++ D+ V +K +T+ +I++ + CK + T ++ K +P Sbjct: 137 EEESEDEDKDVVLKSDAITKYYTIKDELGKGRFGVVCKCVNKKTGKQFAAKFIKCSKP 194 Score = 45.2 bits (102), Expect = 0.001 Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 15/160 (9%) Query: 3688 EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747 +D PP F ++KD + EG F+C++ G+P ++W+ NG ++ L Sbjct: 20 DDVPKGPPVFKQKLKD-CKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFL 76 Query: 3748 NDFGF-IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806 D L I DAGEY A N+ G K++CSAK +++ +P E Sbjct: 77 YDENDNCKLIITEGKHADAGEYKVVAENRHG------KVSCSAK--LIINDPVPS--DDE 126 Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846 + E IS+ E+ K K +T+++ G Sbjct: 127 SASDAE-SDISEEESEDEDKDVVLKSDAITKYYTIKDELG 165 Score = 44.4 bits (100), Expect = 0.002 Identities = 20/53 (37%), Positives = 27/53 (50%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162 PPVF + EG ARF C++TG+P+P V W NG + + YD Sbjct: 26 PPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYD 78 Score = 43.6 bits (98), Expect = 0.004 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899 V + P Q K+ EG +A +EC+I P+P VEWY NG++L+ + D Sbjct: 22 VPKGPPVFKQKLKDCKIIEGSAARFECQITGNPEP--EVEWYRNGELLKECKQLTFLYDE 79 Query: 1900 GFAALDILTV-YGEDSGEYTCKAINNLGQAVSSIRL 1934 I+T D+GEY A N G+ S +L Sbjct: 80 NDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKL 115 Score = 41.9 bits (94), Expect = 0.012 Identities = 26/92 (28%), Positives = 50/92 (54%), Gaps = 5/92 (5%) Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201 D KG P F +++ + + +G +A FEC + +P+ ++EWY NG+ ++ ++ + Sbjct: 21 DVPKGP-PVFKQKLKDCK-IIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFL 76 Query: 3202 SDFG-FVVLDIAYTQNHDSGEYVCRAYNKYGE 3232 D L I ++ D+GEY A N++G+ Sbjct: 77 YDENDNCKLIITEGKHADAGEYKVVAENRHGK 108 Score = 41.5 bits (93), Expect = 0.016 Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 4/87 (4%) Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029 K PP F +++ ++E +FECQ+ G+P +VEW+ NG+ L + T +YD Sbjct: 24 KGPPVFKQKLKD-CKIIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFLYDEN 80 Query: 4030 -YVAMNFGWVYPEDSGEYLCRATNLYG 4055 + D+GEY A N +G Sbjct: 81 DNCKLIITEGKHADAGEYKVVAENRHG 107 Score = 41.1 bits (92), Expect = 0.021 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 4/96 (4%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG-LV 2700 P+F LK K++EG E Q+ +P ++EW++NG L +L +D Sbjct: 27 PVFKQKLKDC-KIIEGSAARFECQITGNPEP--EVEWYRNGELLKECKQLTFLYDENDNC 83 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 L I ++ D+G Y A N G+ +A + I D Sbjct: 84 KLIITEGKHADAGEYKVVAENRHGKVSCSAKLIIND 119 Score = 40.7 bits (91), Expect = 0.028 Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 5/137 (3%) Query: 622 RPYIPPGEEDRVYP-PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIE 680 RP + D V PP F LK +EG FE +I G+P ++EW +NG+ ++ Sbjct: 11 RPNVVGNSTDDVPKGPPVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLK 68 Query: 681 ASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT-PRATIERTS 738 + T ++ L + D+GEY A + G A L + P + + ++ Sbjct: 69 ECKQLTFLYDENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPSDDESA 128 Query: 739 QHPETLQYIQQLEDYSK 755 E+ ++ ED K Sbjct: 129 SDAESDISEEESEDEDK 145 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 4/92 (4%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFG-FV 3478 PVF L + + + EG A FE ++T +P +VEWY NG+ LK + D Sbjct: 27 PVFKQKLKDCKII-EGSAARFECQITGNPEP--EVEWYRNGELLKECKQLTFLYDENDNC 83 Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASM 3510 L I+ D+GEY A N +G+ +A + Sbjct: 84 KLIITEGKHADAGEYKVVAENRHGKVSCSAKL 115 Score = 38.3 bits (85), Expect = 0.15 Identities = 21/89 (23%), Positives = 38/89 (42%), Gaps = 1/89 (1%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR-IHTDGGASTLD 549 P F ++ + EG + G P P + W ++G + +L ++ + L Sbjct: 27 PVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKLI 86 Query: 550 IPRAKASDAAWYQCTAQNVAGSTATRARL 578 I K +DA Y+ A+N G + A+L Sbjct: 87 ITEGKHADAGEYKVVAENRHGKVSCSAKL 115 Score = 36.7 bits (81), Expect = 0.46 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 3/94 (3%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG-YVA 2036 P F + +K+ ++ EG E +T +P VEWY NG +++ + YD Sbjct: 27 PVFKQKLKDCKIIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFLYDENDNCK 84 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 L I D G Y A N G+ ++ + ++ Sbjct: 85 LIITEGKHADAGEYKVVAENRHGKVSCSAKLIIN 118 Score = 35.9 bits (79), Expect = 0.80 Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 9/104 (8%) Query: 1571 DEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT--- 1627 D+V P+ LK+ +I EG A FE ++ + +VEWY N + LK + T Sbjct: 20 DDVPKGPPVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFLY 77 Query: 1628 -ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 E +N L I D+G Y A N G+ S I++ Sbjct: 78 DENDN---CKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIIN 118 Score = 35.5 bits (78), Expect = 1.1 Identities = 33/139 (23%), Positives = 60/139 (43%), Gaps = 14/139 (10%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK-LTSDFGFVTLDLVDVYERD 2980 +++EG E Q+ +P+ ++EWY NG++L++ + L + L + + D Sbjct: 37 KIIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFLYDENDNCKLIITEGKHAD 94 Query: 2981 SGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQP 3040 +G Y A N+ G+ V C++K LI P E + E + +E + Sbjct: 95 AGEYKVVAENRHGK------VSCSAK--LIINDPVPSDD---ESASDAESDISEEESEDE 143 Query: 3041 DDDTGRPPEFTTVFKDIVD 3059 D D + T + I D Sbjct: 144 DKDVVLKSDAITKYYTIKD 162 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 3/90 (3%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSL 2833 VF L + EG FEC + + +P ++EW+ N + L + +D + L Sbjct: 28 VFKQKLKDCKIIEGSAARFECQITGNPEP--EVEWYRNGELLKECKQLTFLYDENDNCKL 85 Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 IT D+G Y A N G + S L Sbjct: 86 IITEGKHADAGEYKVVAENRHGKVSCSAKL 115 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 4/84 (4%) Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG-FV 2566 P+F Q L ++ EG A +E ++ G+P EWY NG LK + +D Sbjct: 27 PVFKQKLKD-CKIIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFLYDENDNC 83 Query: 2567 TLDINSVVANDAGLYMCKAINRAG 2590 L I DAG Y A NR G Sbjct: 84 KLIITEGKHADAGEYKVVAENRHG 107 >SB_26454| Best HMM Match : I-set (HMM E-Value=7e-12) Length = 136 Score = 72.5 bits (170), Expect = 8e-12 Identities = 42/125 (33%), Positives = 68/125 (54%), Gaps = 4/125 (3%) Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE--RFSTLNVREG 505 ++L + ++ DSG VA+N G+ Q L V KE++ AP+F E R + L E Sbjct: 2 YSLTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVV--KEKLFAPEFDEAQRSAPLVFEEE 59 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 + ++LN + +GTP P + W K+G + + +L I + G L + +A A DA Y+C A Sbjct: 60 DEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEA 119 Query: 566 QNVAG 570 +N G Sbjct: 120 KNKMG 124 Score = 65.3 bits (152), Expect = 1e-09 Identities = 42/135 (31%), Positives = 67/135 (49%), Gaps = 13/135 (9%) Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-KPQTKAANAPPEIIE 4627 Y+L + + DSG Y+ VA N+ G+ + A VV K+K P+ A ++ Sbjct: 2 YSLTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVV-----KEKLFAPEFDEAQRSAPLVF 56 Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687 +D+I+ + KI+G P P V WYK + + S +++ D Y LR+ +A Sbjct: 57 EEEDEIM-------LNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAA 109 Query: 4688 EDEGDYKCVAYNSAG 4702 +D G+YKC A N G Sbjct: 110 DDAGEYKCEAKNKMG 124 Score = 56.4 bits (130), Expect = 5e-07 Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 9/128 (7%) Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 L +R + +DS + VA+N G + A LVV+EK + P F ++ + Sbjct: 4 LTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVVKEK-------LFAPEFDEAQRSAPLVF 56 Query: 4528 GQL--VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585 + + L+ K+ GT +V W KNG+++ + +I Y L + +A D+G+Y+ Sbjct: 57 EEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYK 116 Query: 4586 CVAINSAG 4593 C A N G Sbjct: 117 CEAKNKMG 124 Score = 56.0 bits (129), Expect = 7e-07 Identities = 34/119 (28%), Positives = 60/119 (50%), Gaps = 5/119 (4%) Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRV 297 + + VG+ VQ + + L P+ + R++ L +E + +++ G P+P V Sbjct: 20 VAQNTVGKCQVQAALVVKEKL---FAPEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEV 76 Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356 W+KNG+RL +SN+ EI + + LRV D+G Y A+N G + + + VE Sbjct: 77 LWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135 Score = 47.6 bits (108), Expect = 2e-04 Identities = 29/123 (23%), Positives = 49/123 (39%) Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737 Y+L + + +D G YK VA N+ G+ V A L V + A +V E Sbjct: 2 YSLTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVVKEKLFAPEFDEAQRSAPLVFEEEDE 61 Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797 +I KP + W + G + ++ ++ G+ L + +D G + C A Sbjct: 62 IMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKN 121 Query: 4798 AAG 4800 G Sbjct: 122 KMG 124 Score = 47.2 bits (107), Expect = 3e-04 Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 3/127 (2%) Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164 M L + K DSGTY A N G+ ++ L V K K P F Q L Sbjct: 1 MYSLTVRDLKRDDSGTYKLVAQNTVGKCQVQAAL--VVKEKLFAPEFD-EAQRSAPLVFE 57 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 + + + P ++ WY NG+ + S +++ S L + D+GEY C Sbjct: 58 EEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKC 117 Query: 3225 RAYNKYG 3231 A NK G Sbjct: 118 EAKNKMG 124 Score = 44.8 bits (101), Expect = 0.002 Identities = 24/93 (25%), Positives = 44/93 (47%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P+F + ++A + + L + P V WY NGR + ++ + T L Sbjct: 43 PEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRL 102 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 + A A+D G Y C+A N +G ++ T ++V+ Sbjct: 103 RVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135 Score = 43.6 bits (98), Expect = 0.004 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 3/97 (3%) Query: 378 ETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435 + + + + EK AP+F + + + E + ++ G P PEV W+ N R++ D Sbjct: 29 QVQAALVVKEKLFAPEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDS 88 Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 N + + + L + D+G C A+NK G Sbjct: 89 -NQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124 Score = 43.6 bits (98), Expect = 0.004 Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858 P V WYK+GR + S+++ I ++G V L + A+DAG Y A NK+G ++ T Sbjct: 72 PKPEVLWYKNGRRLFDSNQL-EITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTF 130 Query: 859 SIRV 862 I+V Sbjct: 131 DIQV 134 Score = 40.7 bits (91), Expect = 0.028 Identities = 20/64 (31%), Positives = 34/64 (53%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P ++ W+KNG L +L+ T + L + DD+G Y C+A N +G ++ T Sbjct: 72 PKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTFD 131 Query: 2732 IKIE 2735 I++E Sbjct: 132 IQVE 135 Score = 39.1 bits (87), Expect = 0.086 Identities = 17/66 (25%), Positives = 34/66 (51%) Query: 2136 INDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVN 2195 + P + W+ NG+++ ++ T L + A+D+G Y C+A NK+G ++ Sbjct: 69 LGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLR 128 Query: 2196 TCTLKV 2201 T ++V Sbjct: 129 TFDIQV 134 Score = 38.7 bits (86), Expect = 0.11 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 3/96 (3%) Query: 1843 APRFI-TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901 AP F Q + P E +I P P V WY NG+ L ++ ++ Sbjct: 42 APEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPE--VLWYKNGRRLFDSNQLEITSYGDV 99 Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 L + +D+GEY C+A N +G ++ + + V+ Sbjct: 100 YRLRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135 Score = 38.3 bits (85), Expect = 0.15 Identities = 21/93 (22%), Positives = 42/93 (45%) Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 AP+F A + V + L+ +G V W+ NG+ + ++ D Sbjct: 42 APEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYR 101 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 L + +D+G Y C+A N++G ++ + ++V Sbjct: 102 LRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQV 134 Score = 37.5 bits (83), Expect = 0.26 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 3/90 (3%) Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027 +K P F + Q LV E + L +G P +V W+ NG+ L N+ I Sbjct: 38 EKLFAPEF-DEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQL-EITS 95 Query: 4028 FGYV-AMNFGWVYPEDSGEYLCRATNLYGM 4056 +G V + +D+GEY C A N G+ Sbjct: 96 YGDVYRLRVFKAAADDAGEYKCEAKNKMGV 125 Score = 37.5 bits (83), Expect = 0.26 Identities = 20/64 (31%), Positives = 29/64 (45%) Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781 +G P + W+ NGR +++ + L + A DAGEY C A NK G + Sbjct: 69 LGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLR 128 Query: 3782 TAKI 3785 T I Sbjct: 129 TFDI 132 Score = 37.1 bits (82), Expect = 0.35 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 4/72 (5%) Query: 94 KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQY 152 K+ G P P V W + L + N+ + GDV L + + D GEY C A+N+ Sbjct: 67 KILGTPKPEVLWYKNGRRLFDSNQLEIT---SYGDVYRLRVFKAAADDAGEYKCEAKNKM 123 Query: 153 GEAICSVYIQPE 164 G ++ + IQ E Sbjct: 124 GVSLRTFDIQVE 135 Score = 36.3 bits (80), Expect = 0.61 Identities = 17/53 (32%), Positives = 25/53 (47%) Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 PK + WY+NG+ L ++ L + A+D+GEY C A N G Sbjct: 72 PKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/94 (24%), Positives = 40/94 (42%) Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 AP F + + + L +G PK V W +NG + SN+L Sbjct: 42 APEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYR 101 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 L + +D+G Y C A N++G ++ + + V+ Sbjct: 102 LRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135 Score = 35.9 bits (79), Expect = 0.80 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508 P +V WY NG+ L ++ +G V L + +D+GEY C A N G ++ T Sbjct: 72 PKPEVLWYKNGRRLFDSNQLE-ITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTF 130 Query: 3509 SMKVQ 3513 ++V+ Sbjct: 131 DIQVE 135 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F + + P V E ++ + L+ +G P V W+ NGR + ++ + Sbjct: 43 PEFDEAQRSAPLVFEEED-EIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYR 101 Query: 1237 LDIIHATSADTGEYTVRAVNHLG 1259 L + A + D GEY A N +G Sbjct: 102 LRVFKAAADDAGEYKCEAKNKMG 124 Score = 34.7 bits (76), Expect = 1.9 Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 4123 EEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGMYHFDIPKTRQYDTGK 4179 EE + ++ G PKP V+W NG + + ++ ++T Y +Y + K D G+ Sbjct: 57 EEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGE 114 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 1/91 (1%) Query: 2234 VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI 2293 V + K+ P F R VFE + ++ + P + +Y NG+ L + + I Sbjct: 35 VVKEKLFAPEFDEAQRSAPLVFEEED-EIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEI 93 Query: 2294 TFDFGYVSLDIQHCVPEDAGEYSVKAINALG 2324 T L + +DAGEY +A N +G Sbjct: 94 TSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124 Score = 34.3 bits (75), Expect = 2.5 Identities = 17/53 (32%), Positives = 27/53 (50%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 P ++ WY NG+ L ++ ++TS L + D+G Y C+A NK G Sbjct: 72 PKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124 Score = 33.9 bits (74), Expect = 3.2 Identities = 12/37 (32%), Positives = 25/37 (67%) Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 +L + ++ +DSG Y +VA+N G+ Q+ A++ V+ + Sbjct: 3 SLTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVVKEK 39 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 1/83 (1%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+F + Q LV + L + P +V W+ NG++L ++ + Sbjct: 43 PEF-DEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYR 101 Query: 3342 LDILYCYEENSGEYECVATNKLG 3364 L + +++GEY+C A NK+G Sbjct: 102 LRVFKAAADDAGEYKCEAKNKMG 124 Score = 33.9 bits (74), Expect = 3.2 Identities = 15/56 (26%), Positives = 28/56 (50%) Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 +G P +V W++N + + DS+++ T + + +D G Y C A N +G Sbjct: 69 LGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124 Score = 33.5 bits (73), Expect = 4.3 Identities = 18/56 (32%), Positives = 25/56 (44%) Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 +G P WY NG L ++ T L + A+DAG Y C+A N+ G Sbjct: 69 LGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124 Score = 33.1 bits (72), Expect = 5.7 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 2/59 (3%) Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-SLDMLSLNIQDSGEYTCRAVSATGVA 720 +G P ++ W KNG+ + S++ I +G + L + D+GEY C A + GV+ Sbjct: 69 LGTPKPEVLWYKNGRRLFDSNQL-EITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVS 126 Score = 32.3 bits (70), Expect = 9.9 Identities = 16/60 (26%), Positives = 30/60 (50%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 V WY NG+++ +N+++ L + A+D+G Y A+N G + + + VE Sbjct: 76 VLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 V W+ NG+ L ++++ I +G V L + DAG Y C+A N+ G + + +QV Sbjct: 76 VLWYKNGRRLFDSNQLE-ITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQV 134 Query: 3650 K 3650 + Sbjct: 135 E 135 >SB_12405| Best HMM Match : I-set (HMM E-Value=8.8e-21) Length = 198 Score = 72.1 bits (169), Expect = 1e-11 Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 13/165 (7%) Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 GT V + + +++ R I+EE+ G + L I P+D+G+Y+C+A+N AGE Sbjct: 13 GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTS 72 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 L ++ PQ P ++E + +G + S ++ G P P ++WY Sbjct: 73 KGY----LHVEEELTIPQF--IGDVPGVVE------LVQGDNYDLSLEVRGTPRPEIEWY 120 Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 ++LI + Q+S + + T+ + +D G Y+C A N+AG Sbjct: 121 HNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165 Score = 70.1 bits (164), Expect = 4e-11 Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 3/156 (1%) Query: 417 GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAF 476 G P P VT+ QI D + I+ E+G L I N D+G C+A N +GE Sbjct: 13 GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTS 72 Query: 477 QCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP 535 + L+V +E++ P+F+ + + + +G+ L+ GTP P I W + I Sbjct: 73 KGYLHV--EEELTIPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATS 130 Query: 536 ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 +++ +T+ + D+ Y+C A N AG+ Sbjct: 131 RVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGT 166 Score = 66.1 bits (154), Expect = 7e-10 Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 10/158 (6%) Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 G P+P V +++ +++ +Y + + L I PED G+Y+C+A N AG VT Sbjct: 13 GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTS 72 Query: 4707 AAKLKV----TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762 L V T P ++P + L +G ++ +P I+W LI Sbjct: 73 KGYLHVEEELTIPQFIGDVPGVVEL-----VQGDNYDLSLEVRGTPRPEIEWYHNERLIY 127 Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 T Q+ + A + + N +D+G + C+A AG Sbjct: 128 ATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165 Score = 56.0 bits (129), Expect = 7e-07 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 2/98 (2%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P+FI + G +L +G + Y+ +E P +EWY N +++ + R + S A Sbjct: 85 PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 + + V +DSG Y CKA+N G +NVQ S Sbjct: 143 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGSS 180 Score = 55.6 bits (128), Expect = 9e-07 Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 33/194 (17%) Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVT 349 G P P VT+ + +++ + ++ I+ N L +RNT+ D+G Y CI Sbjct: 13 GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQ--------CIAV 64 Query: 350 SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV-KVCQDRDVTEGKM 408 +G A E ++ Y + + E+ PQF+ V ++ +G Sbjct: 65 NG--AGEVTSKGY--------------------LHVEEELTIPQFIGDVPGVVELVQGDN 102 Query: 409 TRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468 V G P PE+ W+ N+R I ++ S + + NVTL DSG+ C A Sbjct: 103 YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISS-KATIALYNVTLDDSGLYRCKAV 161 Query: 469 NKSGETAFQCRLNV 482 N +G + Q +NV Sbjct: 162 NTAGTGSKQFNINV 175 Score = 51.6 bits (118), Expect = 2e-05 Identities = 36/137 (26%), Positives = 62/137 (45%), Gaps = 4/137 (2%) Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 G+ VL I T+ D+G Y C A N G E++ K + + P+F + + L Sbjct: 42 GLFVLTIRNTRPEDAGEYQCIAVN--GAGEVTSKGYLHVEEELTIPQFIGDVPGVVELVQ 99 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G +++ ++ P +IEWYHN + + ++R++ + + DSG Y Sbjct: 100 GD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYR 157 Query: 3224 CRAYNKYGEDFTRATIN 3240 C+A N G + IN Sbjct: 158 CKAVNTAGTGSKQFNIN 174 Score = 51.2 bits (117), Expect = 2e-05 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 7/160 (4%) Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493 +G P+P + ++RE+ I + + I + +L IR ED+ + +A N G Sbjct: 12 EGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVT 71 Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553 L VEE+ +P V + G L +V GT ++ W N + Sbjct: 72 SKGYLHVEEELT------IPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERL 125 Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593 + R ++ T+ + DSG Y C A+N+AG Sbjct: 126 IYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165 Score = 51.2 bits (117), Expect = 2e-05 Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 5/117 (4%) Query: 1024 EDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNG 1083 E S+ EEE+ I P+F+G + G ++V+G + ++ +E + +EWY N Sbjct: 69 EVTSKGYLHVEEELTI---PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNE 123 Query: 1084 KQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140 + I + +R+Q + + +V +DSG+Y A N AG ++ V+ SS Sbjct: 124 RLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGSS 180 Score = 49.6 bits (113), Expect = 6e-05 Identities = 27/94 (28%), Positives = 48/94 (51%), Gaps = 2/94 (2%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P F + +LV+G + L +V R P +IEW+ N + +R++ +F T Sbjct: 85 PQFIGDVPGVVELVQGDNYDLSLEV--RGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 +++ ++ DDSG+Y CKA N G +I ++ Sbjct: 143 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQ 176 Score = 48.8 bits (111), Expect = 1e-04 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 3/106 (2%) Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821 +EE+ + PQFI + + EL +G N ++ L P +EWY + R I A+SR+ Sbjct: 78 VEEELTI-PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQL 134 Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARST 867 F ++ + ++ +D+G Y +AVN G +I V S+ Sbjct: 135 SFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGSS 180 Score = 48.8 bits (111), Expect = 1e-04 Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Query: 3828 TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887 T P+FI + VE +G ++ +E + P+ IEWY N +L+ + R + + Sbjct: 83 TIPQFIGDVPG-VVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKA 141 Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923 ++ + V +DSG Y C+AVN G + I+ ++ Sbjct: 142 TIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQR 177 Score = 48.8 bits (111), Expect = 1e-04 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 PQFI + V + G +++ +E G P +IEW N + I A+SR F ++ Sbjct: 85 PQFIGDVPGVVELVQGD-NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATI 143 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + ++ + DSG Y C+AV+ G + ++V Sbjct: 144 ALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV 175 Score = 48.4 bits (110), Expect = 1e-04 Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 2/89 (2%) Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964 + E P++I + +LV+G L +E + P +IEWY N +++ SR +L+ Sbjct: 79 EEELTIPQFIGDVPGVVELVQGDNYDLS--LEVRGTPRPEIEWYHNERLIYATSRVQLSF 136 Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 T+ L +V DSG+Y CKA N G Sbjct: 137 ISSKATIALYNVTLDDSGLYRCKAVNTAG 165 Score = 47.6 bits (108), Expect = 2e-04 Identities = 24/103 (23%), Positives = 55/103 (53%), Gaps = 3/103 (2%) Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291 + VEE +++ P+F+ ++ G + +G +++ +E P IE+YHN + + + +R Sbjct: 76 LHVEE-ELTIPQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRV 132 Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 ++F ++ + + +D+G Y KA+N G + ++ V Sbjct: 133 QLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV 175 Score = 47.6 bits (108), Expect = 2e-04 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 2/100 (2%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961 V E P+F + + + +G +++ LE G +EW + R + A+SR+ Sbjct: 78 VEEELTIPQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLS 135 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 F + + +VT+ D+G Y C+A N G + N+ + Sbjct: 136 FISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV 175 Score = 46.0 bits (104), Expect = 8e-04 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 2/89 (2%) Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561 + E P F + G EL +G + Y+ + G P EWY N + SR + + Sbjct: 79 EEELTIPQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSF 136 Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590 T+ + +V +D+GLY CKA+N AG Sbjct: 137 ISSKATIALYNVTLDDSGLYRCKAVNTAG 165 Score = 46.0 bits (104), Expect = 8e-04 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P+F +V++ +G +Y+ SL G IEW++N + I A+ R++ + Sbjct: 85 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142 Query: 3108 LEILGTKTTDSGTYSCRATNKWG 3130 + + DSG Y C+A N G Sbjct: 143 IALYNVTLDDSGLYRCKAVNTAG 165 Score = 45.6 bits (103), Expect = 0.001 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P F + + + +G ++D L G P ++EW+ NE+LI +SR+ + + Sbjct: 85 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 + + +V +D G+Y C+A N G Sbjct: 143 IALYNVTLDDSGLYRCKAVNTAG 165 Score = 43.6 bits (98), Expect = 0.004 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 G P P V++ R+ + + +YS+ E+ G L I+ P D GEY C A N GE Sbjct: 13 GTPVPAVTFHRESEQIYDGGRYSI-VEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVT 71 Query: 157 CSVYIQPE 164 Y+ E Sbjct: 72 SKGYLHVE 79 Score = 43.6 bits (98), Expect = 0.004 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 9/102 (8%) Query: 3679 LHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF 3738 LH EE+TI P+F ++ +++ +G ++D +E G P I+W+HN R Sbjct: 76 LHVEEELTI-------PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLI 126 Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780 SRV + + + D+G Y C+A N G+ + Sbjct: 127 YATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGS 168 Score = 43.6 bits (98), Expect = 0.004 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 3/104 (2%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F+ + + +G N L LE G P +EW+HN R + SR + + Sbjct: 85 PQFIGDVPGVVELVQGDNYDLS--LEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280 + + + T D+G Y +AVN G+ + V +R D Q Sbjct: 143 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV-QRGSSRVDLQ 185 Score = 43.6 bits (98), Expect = 0.004 Identities = 23/84 (27%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Query: 2776 FISHLNNIV-CKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 FI + +V +GDN ++ ++E P +IEW+ N + + + +R + + S ++ Sbjct: 87 FIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIA 144 Query: 2835 ITHTYEEDSGIYTCKATNSKGSAT 2858 + + +DSG+Y CKA N+ G+ + Sbjct: 145 LYNVTLDDSGLYRCKAVNTAGTGS 168 Score = 42.7 bits (96), Expect = 0.007 Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 3/92 (3%) Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495 ++E +TI P+F+ + +++G + ++ LE ++EW+ N + + R + Sbjct: 78 VEEELTI-PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQL 134 Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527 + + ++ +DSG+Y C+AVN GT Sbjct: 135 SFISSKATIALYNVTLDDSGLYRCKAVNTAGT 166 Score = 42.7 bits (96), Expect = 0.007 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F+ + + L +GD +++ +E P I+W+HN + I A R + + Sbjct: 85 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142 Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191 + + +DSG Y CKA N G Sbjct: 143 IALYNVTLDDSGLYRCKAVNTAG 165 Score = 41.5 bits (93), Expect = 0.016 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 6/93 (6%) Query: 1301 VREDITVMQAPQFSRALHNI-ETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRF 1359 V E++T+ PQF + + E V+G N L ++ G +EW+ N + I R Sbjct: 78 VEEELTI---PQFIGDVPGVVELVQGDNYDLSLEVR--GTPRPEIEWYHNERLIYATSRV 132 Query: 1360 RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392 + ++ + L +V +DSG+Y C+A N G Sbjct: 133 QLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165 Score = 41.1 bits (92), Expect = 0.021 Identities = 20/81 (24%), Positives = 38/81 (46%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 P I P +L +G + +++ G PRP + W+ N + + +++ ++ + T+ Sbjct: 85 PQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIA 144 Query: 325 VRNTQKSDSGHYTLLAENPNG 345 + N DSG Y A N G Sbjct: 145 LYNVTLDDSGLYRCKAVNTAG 165 Score = 40.3 bits (90), Expect = 0.037 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 6/98 (6%) Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFT--ETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 +P V ++ ++ + G R++ E N G L I + PED+G Y C A+N G Sbjct: 10 VPEGTPVPAVTFHRESEQIYDGGRYSIVEEEN-GLFVLTIRNTRPEDAGEYQCIAVNGAG 68 Query: 1660 EAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKY 1697 E + G V + +I Q G +P + +L Y Sbjct: 69 EVTSKGYLHVEEELTI---PQFIGDVPGVVELVQGDNY 103 Score = 40.3 bits (90), Expect = 0.037 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 3/110 (2%) Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473 EE+ P F + + L +G+N ++ L P ++EWY N + + A SR + Sbjct: 79 EEELTIPQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSF 136 Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ-GKRNIILES 3522 + + +DSG Y C+A N G ++ VQ G + L++ Sbjct: 137 ISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGSSRVDLQA 186 Score = 39.1 bits (87), Expect = 0.086 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGE 1793 +P G P V + R I R + + + G L ++ PED+G Y C A+N GE Sbjct: 10 VPEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGE 69 Query: 1794 AVTSSTLFVQSKASL 1808 + L V+ + ++ Sbjct: 70 VTSKGYLHVEEELTI 84 Score = 39.1 bits (87), Expect = 0.086 Identities = 22/82 (26%), Positives = 37/82 (45%) Query: 1726 QAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785 Q +++ L G P+ +EW N I A++R+ + + V +DSG Y C Sbjct: 99 QGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRC 158 Query: 1786 RAINELGEAVTSSTLFVQSKAS 1807 +A+N G + VQ +S Sbjct: 159 KAVNTAGTGSKQFNINVQRGSS 180 Score = 38.7 bits (86), Expect = 0.11 Identities = 20/70 (28%), Positives = 34/70 (48%) Query: 4432 VEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491 +E G P P I+WY I + Q+ S+K+ + + V ++DS ++ A N GT Sbjct: 107 LEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGT 166 Query: 4492 AKCSANLVVE 4501 N+ V+ Sbjct: 167 GSKQFNINVQ 176 Score = 37.9 bits (84), Expect = 0.20 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 662 PVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVA 720 P G P + + + + I R++ + G L + + +D+GEY C AV+ G Sbjct: 11 PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70 Query: 721 ETKAVLHVTPRATI 734 +K LHV TI Sbjct: 71 TSKGYLHVEEELTI 84 Score = 37.9 bits (84), Expect = 0.20 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625 +L+ +N E R P + +EW+HN + + SRV+ + + V Sbjct: 96 ELVQGDNYDLSLEVRGTPRPE----IEWYHNERLIYATSRVQLSFISSKATIALYNVTLD 151 Query: 3626 DAGLYTCKATNRHGEATVSCKLQVK 3650 D+GLY CKA N G + + V+ Sbjct: 152 DSGLYRCKAVNTAGTGSKQFNINVQ 176 Score = 37.1 bits (82), Expect = 0.35 Identities = 15/50 (30%), Positives = 27/50 (54%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 ++EWYHN + + + SR + + + + +DSG Y C+A+N G Sbjct: 116 EIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 1870 PYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928 P P V ++ + + G RY + G L I ED+GEY C A+N G+ Sbjct: 11 PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70 Query: 1929 VSSIRLNVQSKESI 1942 S L+V+ + +I Sbjct: 71 TSKGYLHVEEELTI 84 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 3446 PTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GFVILEISPTYPEDSGEYLCRAYNNYGEA 3504 P P V ++ + + G R+ + G +L I T PED+GEY C A N GE Sbjct: 11 PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70 Query: 3505 VTTASMKVQGKRNI 3518 + + V+ + I Sbjct: 71 TSKGYLHVEEELTI 84 Score = 36.7 bits (81), Expect = 0.46 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 1/65 (1%) Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNA-VLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 P + + RE I + + ++ E N VL I NT ED G + C A AG+V + L Sbjct: 17 PAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYL 76 Query: 4809 VVKSK 4813 V+ + Sbjct: 77 HVEEE 81 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 3/97 (3%) Query: 1978 PQFGKPIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036 PQF + E+ +G + + +L P +EWY N R + R + ++ Sbjct: 85 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142 Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073 + + +D+G Y CKA N G ++ V S Sbjct: 143 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGS 179 Score = 36.3 bits (80), Expect = 0.61 Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 2/91 (2%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341 P+FI + V +LV+G + ++ L P ++EW++N + + R + Sbjct: 85 PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142 Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372 + + ++SG Y C A N G S + N+ Sbjct: 143 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNI 173 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%) Query: 2401 IPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLGE 2459 +P G P V + R + I D R + + G +TI + R ED G Y C A N GE Sbjct: 10 VPEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGE 69 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Query: 3855 PKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGED 3913 P+ P + ++R + + G RY V + G L I ED+GEY C AVN GE Sbjct: 11 PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70 Query: 3914 FTK 3916 +K Sbjct: 71 TSK 73 Score = 35.5 bits (78), Expect = 1.1 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 2268 PVHDPNLRIEFYHNGKALQSAARFHITFDF-GYVSLDIQHCVPEDAGEYSVKAINALGHC 2326 P P + F+ + + R+ I + G L I++ PEDAGEY A+N G Sbjct: 11 PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70 Query: 2327 TS 2328 TS Sbjct: 71 TS 72 Score = 35.1 bits (77), Expect = 1.4 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 1/79 (1%) Query: 796 PVSDPTMRVEWYKDGRPITASSRITSIFNF-GYVSLNIMHLRAEDAGSYTVRAVNKLGEA 854 P P V ++++ I R + + G L I + R EDAG Y AVN GE Sbjct: 11 PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70 Query: 855 ISTASIRVAARSTVTADLG 873 S + V T+ +G Sbjct: 71 TSKGYLHVEEELTIPQFIG 89 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Query: 3307 VPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIVILDILYCYEENSGEYECVATNKLGR 3365 VP P V + +++ G RY + G+ +L I E++GEY+C+A N G Sbjct: 10 VPEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGE 69 Query: 3366 DSTKANL 3372 ++K L Sbjct: 70 VTSKGYL 76 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P+F+ + LV+ + ++ L G P ++EW+ N + + +R + Sbjct: 85 PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142 Query: 4033 MNFGWVYPEDSGEYLCRATNLYG 4055 + V +DSG Y C+A N G Sbjct: 143 IALYNVTLDDSGLYRCKAVNTAG 165 Score = 33.5 bits (73), Expect = 4.3 Identities = 15/39 (38%), Positives = 22/39 (56%) Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 GL L+I + R +D+G Y C A N GE S + +E+ Sbjct: 42 GLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEE 80 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Query: 1069 PQSDLTMTVEWYFNGKQITSANRIQTYHDF-GYVALDIASVRAEDSGVYTVVARNAAGEA 1127 P+ V ++ +QI R + G L I + R ED+G Y +A N AGE Sbjct: 11 PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70 Query: 1128 QLSASMTVETRSSI 1141 + VE +I Sbjct: 71 TSKGYLHVEEELTI 84 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 2135 PINDPHLTIDWFHNGQKIRAGHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEA 2193 P P + + ++I G RY + G L I T ED+G Y C A N GE Sbjct: 11 PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70 Query: 2194 VNTCTLKV 2201 + L V Sbjct: 71 TSKGYLHV 78 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 2799 PSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LDITHTYEEDSGIYTCKATNSKGSA 2857 P P + + ++ + G RY + + + L I +T ED+G Y C A N G Sbjct: 11 PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70 Query: 2858 TTSGSL 2863 T+ G L Sbjct: 71 TSKGYL 76 Score = 32.3 bits (70), Expect = 9.9 Identities = 14/37 (37%), Positives = 19/37 (51%) Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 G LTI++ DAG Y C A N G+ T+ L + Sbjct: 42 GLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHV 78 >SB_11883| Best HMM Match : I-set (HMM E-Value=0) Length = 616 Score = 69.7 bits (163), Expect = 5e-11 Identities = 78/289 (26%), Positives = 115/289 (39%), Gaps = 33/289 (11%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G PLP+I W R I N+ + I V+D+ ++ VA N G S Sbjct: 347 GFPLPVISWRRGGQAINNTQSALRYR--------IENARVKDTGIYTCVARNLVGYDYSS 398 Query: 4496 ANLVVEEKR----RQGRGGIV----PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547 +N+ + + R + T +NV SG V L TG + W Sbjct: 399 SNISIVAAKPPIIRTSTHHLTVLRRDKISTDLGKNVTTLSGNTVSLLCNATGVPSPKLSW 458 Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV---S 4604 K+G+ + ++ + +L TL L P DSG Y C A N G D+ V S Sbjct: 459 YKDGETL--NVSHAVL------TLPTLS--PSDSGLYRCEARNLKGVDDADSYLTVLVGS 508 Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664 P+ + + T+ N + D I +E +C + G PLP++ W K + +K Sbjct: 509 PPSIRTTSENITETENIAYIVTGIGSDVITLLSSNVEVTCPVRGFPLPSITWLKDGQPLK 568 Query: 4665 PSKYFQMSR-TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 S +++ T Y L I E G Y CVA NS G T L V Sbjct: 569 QSMTVKVNNLTGTLYLLSILE---RRAGLYMCVATNSLGAATATTTLNV 614 Score = 63.3 bits (147), Expect = 5e-09 Identities = 73/296 (24%), Positives = 112/296 (37%), Gaps = 51/296 (17%) Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347 + G P P +TW KNG L + + H L + + DSG Y A N G Sbjct: 237 ETEGLPAPNITWKKNGVALPVDGR---MYARGHI-LFIAESLTRDSGVYICEATNIAGSK 292 Query: 348 VTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407 L V +P E IT T QR EE +S +++ + ++T Sbjct: 293 QAKSELKVIAPVEPV--------ITATVQR-LEELRPVSITTEVGSYIRTLETSNLT--- 340 Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467 C V G P P ++W + I N I N + D+G+ TCVA Sbjct: 341 ---LVCTVRGFPLPVISWRRGGQAIN---------NTQSALRYRIENARVKDTGIYTCVA 388 Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL-----------NVR--EGEPVVLNARA 514 RN G ++++ + + + L NV G V L A Sbjct: 389 RNLVGYDYSSSNISIVAAKPPIIRTSTHHLTVLRRDKISTDLGKNVTTLSGNTVSLLCNA 448 Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 G P+P+++W KDG + + + L +P SD+ Y+C A+N+ G Sbjct: 449 TGVPSPKLSWYKDGETL----------NVSHAVLTLPTLSPSDSGLYRCEARNLKG 494 Score = 56.0 bits (129), Expect = 7e-07 Identities = 75/313 (23%), Positives = 116/313 (37%), Gaps = 39/313 (12%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 P + Q + + + + G ++ W KNG + D R + G + L I Sbjct: 215 PLGLVIGQTARTLTRIIFNITCETEGLPAPNITWKKNGVALPVDGR---MYARG-HILFI 270 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK-DKPKPQTKAANAPPEIIEPLKDK 4632 E+ +DSG Y C A N AG + +E V P Q P I + Sbjct: 271 AESLTRDSGVYICEATNIAGSKQAKSELKVIAPVEPVITATVQRLEELRPVSITTEVGSY 330 Query: 4633 I-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691 I E + C + G PLP + W +G + I + T RI A +D G Sbjct: 331 IRTLETSNLTLVCTVRGFPLPVISWRRGGQAI--------NNTQSALRYRIENARVKDTG 382 Query: 4692 DYKCVA-------YNSAGRVTVAAKLKVTQPDQADNLPAL------TPL-RDIVVYEGQP 4737 Y CVA Y+S+ VAAK + + +L L T L +++ G Sbjct: 383 IYTCVARNLVGYDYSSSNISIVAAKPPIIR-TSTHHLTVLRRDKISTDLGKNVTTLSGNT 441 Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797 T P + W ++G ET + ++AVL + D+G + C A Sbjct: 442 VSLLCNATGVPSPKLSWYKDG----ETLNV------SHAVLTLPTLSPSDSGLYRCEARN 491 Query: 4798 AAGQVETSAKLVV 4810 G + + L V Sbjct: 492 LKGVDDADSYLTV 504 Score = 56.0 bits (129), Expect = 7e-07 Identities = 112/468 (23%), Positives = 166/468 (35%), Gaps = 97/468 (20%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P + W +NGV + R+ ++A ++ DSG Y C A N G Sbjct: 240 GLPAPNITWKKNGVALPVDGRMYARGHILFIAESLT----RDSGVYICEATNIAGSKQAK 295 Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857 S L K +E + +Q++++L S T++ + Sbjct: 296 SEL----KVIAPVEPVITATVQRLEELRPVS-----------------ITTEVGSYIRTL 334 Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVL---QSGHRYRTSNDFGFAALDILTVYGEDS 1914 E + C + +P P + W G+ + QS RYR N +D+ Sbjct: 335 ETSNLTLVCTVRGFPLPV--ISWRRGGQAINNTQSALRYRIEN-----------ARVKDT 381 Query: 1915 GEYTCKAINNLGQAVSSIRLN-VQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSF 1973 G YTC A N +G SS ++ V +K IIR S H + + + D Sbjct: 382 GIYTCVARNLVGYDYSSSNISIVAAKPPIIRTSTHHLTVLRRDKISTD------------ 429 Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033 GK N G+ V L T V P+ ++ WY +G + H Sbjct: 430 ------LGK---NVTTLSGNTVSLLCNATGV--PSPKLSWYKDGETLNVSH--------- 469 Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEK 2093 L + D+G Y C+A N G S + V S + T E I E E Sbjct: 470 -AVLTLPTLSPSDSGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTTSEN----ITETEN 524 Query: 2094 YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR 2153 I G +T L+S C V P +T W +GQ ++ Sbjct: 525 ------IAYIVTGIGSDVITLLSS--------NVEVTCPVRGFPLPSIT--WLKDGQPLK 568 Query: 2154 AGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + + G L +L +G YMC ATN LG A T TL V Sbjct: 569 QSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATATTTLNV 614 Score = 54.8 bits (126), Expect = 2e-06 Identities = 110/465 (23%), Positives = 177/465 (38%), Gaps = 94/465 (20%) Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261 E G P + W NG ++ V R Y G + L I + + D+G Y A N GS Sbjct: 237 ETEGLPAPNITWKKNGVALPVDGRM---YARGHI-LFIAESLTRDSGVYICEATNIAGSK 292 Query: 1262 HTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIE 1321 + ++VI + V T Q +E+++ + +R Sbjct: 293 QAKSELKVIAPVEPVI-TATVQRLEELRPVSITTEVGSYIR------------------- 332 Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK-TGHRFRPAYEFDYVALDLLSVYPEDS 1380 T+E +N+ L C ++ G + W G+ I T R Y + + +D+ Sbjct: 333 TLETSNLTLVCTVR--GFPLPVISWRRGGQAINNTQSALR--YRIENARV-------KDT 381 Query: 1381 GVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESV 1440 G+YTC A N +G +S + ++A K I+ + +L R K + + ++V Sbjct: 382 GIYTCVARNLVGYDYSSSNISIVAAKPPIIRTS-------THHLTVLRRDKISTDLGKNV 434 Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG 1500 T + G V C V K+ W+K+G+ + + H Sbjct: 435 T--------------TLSGNTVSLLCNATGVPSP--KLSWYKDGETLNVSH--------- 469 Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR-STTDIVRSTQNEAGLEQIQVLE 1559 L + L DSG+Y C A NL G D+ LT + +R+T E I E Sbjct: 470 -AVLTLPTLSPSDSGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTTS-----ENITETE 523 Query: 1560 DRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKP 1619 + + Y T + +V T NVE+ R P+ T W + +P Sbjct: 524 NIA-YIVTGIGSDVITLLS------SNVEVTCPVRG------FPLPSIT----WLKDGQP 566 Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664 LK N G L ++S L +G Y C A N+LG A + Sbjct: 567 LKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATAT 609 Score = 52.0 bits (119), Expect = 1e-05 Identities = 71/304 (23%), Positives = 121/304 (39%), Gaps = 61/304 (20%) Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 G P P ++W + GQ + N T + R+ N + D+G YT +A N G +S Sbjct: 347 GFPLPVISWRRGGQAINN--------TQSALRYRIENARVKDTGIYTCVARNLVGYDYSS 398 Query: 351 GYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410 +++ + ++ T T R +IS + ++ G Sbjct: 399 SNISIVAAKPPIIR-------TSTHHLTVLRRDKIS--------TDLGKNVTTLSGNTVS 443 Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470 C TG P P+++W+ + + + +H +L + ++ SDSG+ C ARN Sbjct: 444 LLCNATGVPSPKLSWYKDGETL--NVSHAVLT---------LPTLSPSDSGLYRCEARNL 492 Query: 471 SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT------------- 517 G L V+ V +P + R ++ N+ E E + +G+ Sbjct: 493 KGVDDADSYLTVL----VGSPPSI-RTTSENITETENIAYIVTGIGSDVITLLSSNVEVT 547 Query: 518 ------PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG- 570 P P ITW KDG P+ + ++++ G TL + A Y C A N G Sbjct: 548 CPVRGFPLPSITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGA 605 Query: 571 STAT 574 +TAT Sbjct: 606 ATAT 609 Score = 46.4 bits (105), Expect = 6e-04 Identities = 49/211 (23%), Positives = 79/211 (37%), Gaps = 27/211 (12%) Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332 +N G +G P P+++W+K+G+ L S H L + SD Sbjct: 432 KNVTTLSGNTVSLLCNATGVPSPKLSWYKDGETLNVS----------HAVLTLPTLSPSD 481 Query: 333 SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392 SG Y A N G YL V + ++ S+ IT+T E I + Sbjct: 482 SGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTT-SENITET------ENIAYIVTGIGS 534 Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452 + + C V G P P +TW + + ++ K+ N +G L + Sbjct: 535 DVITLLSSN-------VEVTCPVRGFPLPSITWLKDGQPLKQSMTVKVN-NLTGT--LYL 584 Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483 ++ +G+ CVA N G LNV+ Sbjct: 585 LSILERRAGLYMCVATNSLGAATATTTLNVL 615 Score = 44.0 bits (99), Expect = 0.003 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 4/80 (5%) Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695 E + +CK G PLPTV+W KG + + SK ++ L + +A D G+Y+C Sbjct: 20 EKAPVTLTCKATGLPLPTVRWIKGGRQL-VSKGHEIVAGG---RLFLGKATLGDSGEYEC 75 Query: 4696 VAYNSAGRVTVAAKLKVTQP 4715 A + G V+ + L++ P Sbjct: 76 TATSPLGYVSAKSNLEIKVP 95 Score = 43.6 bits (98), Expect = 0.004 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 8/132 (6%) Query: 3521 ESQLPKGMEGTIDKIAALEGYSGTVDTLTPE-AESGNPPEFTT-TPSDLILSENSSAHFE 3578 E++ KG++ + L G ++ T + E+ N T SD+I +S+ Sbjct: 488 EARNLKGVDDADSYLTVLVGSPPSIRTTSENITETENIAYIVTGIGSDVITLLSSNVEVT 547 Query: 3579 CRLIPVNDSSM-RVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNR 3637 C PV + + W +G+PL VK N G + L + +R AGLY C ATN Sbjct: 548 C---PVRGFPLPSITWLKDGQPLKQSMTVKVNNLTGTLYLL--SILERRAGLYMCVATNS 602 Query: 3638 HGEATVSCKLQV 3649 G AT + L V Sbjct: 603 LGAATATTTLNV 614 Score = 43.2 bits (97), Expect = 0.005 Identities = 44/171 (25%), Positives = 60/171 (35%), Gaps = 26/171 (15%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C G P P +TW N + D + H L I DSGV C A N +G Sbjct: 236 CETEGLPAPNITWKKNGVALPVDGRMY-----ARGHILFIAESLTRDSGVYICEATNIAG 290 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERF-------------STLNVREGEPVVLNARAVGTPT 519 + L VI + V V+R S + E + L G P Sbjct: 291 SKQAKSELKVIAPVEPVITATVQRLEELRPVSITTEVGSYIRTLETSNLTLVCTVRGFPL 350 Query: 520 PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 P I+W++ G I+ A I A+ D Y C A+N+ G Sbjct: 351 PVISWRRGG--------QAINNTQSALRYRIENARVKDTGIYTCVARNLVG 393 Score = 41.9 bits (94), Expect = 0.012 Identities = 101/476 (21%), Positives = 176/476 (36%), Gaps = 93/476 (19%) Query: 929 FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988 F E G + W K+G + R+ + G++ +S+T D+G Y C A N Sbjct: 232 FNITCETEGLPAPNITWKKNGVALPVDGRM---YARGHILFIAESLT-RDSGVYICEATN 287 Query: 989 AIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGP 1048 G + L ++ + + + +Q LE+ S TE ++ Sbjct: 288 IAGSKQAKSELKVIAPVEPVITAT-------VQRLEELRPVSITTEVG-------SYIRT 333 Query: 1049 LKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASV 1108 L+ +N + F V + W G+ I + Y I + Sbjct: 334 LETSNLTLVCTVRGFPLPV---------ISWRRGGQAINNTQSALRYR--------IENA 376 Query: 1109 RAEDSGVYTVVARNAAGEAQLSASMT-VETRSSIDTSSIHRGLYEKTRHIEESKFVEPMY 1167 R +D+G+YT VARN G S++++ V + I +S H H+ + Sbjct: 377 RVKDTGIYTCVARNLVGYDYSSSNISIVAAKPPIIRTSTH--------HLT-------VL 421 Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227 + ++IS V LS G + L C G P+ ++ W+ +G ++ V Sbjct: 422 RRDKISTDLGKNVTTLS-------GNTVSLLCNAT--GVPSPKLSWYKDGETLNVSH--- 469 Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQ 1287 L + + +D+G Y A N G + + V+ S T +E E Sbjct: 470 -------AVLTLPTLSPSDSGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTTSENITET 522 Query: 1288 IQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWF 1347 E+ A + D+ T+ +NV + C ++ G + W Sbjct: 523 ----ENIAYIVTGIGSDVI---------------TLLSSNVEVTCPVR--GFPLPSITWL 561 Query: 1348 CNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 +G+P+K + L LLS+ +G+Y C ATN LG A + L V+ Sbjct: 562 KDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATATTTLNVL 615 Score = 39.9 bits (89), Expect = 0.049 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P I W KNGV L R+ + G + SL D SG+Y C+ATN+ G + + Sbjct: 242 PAPNITWKKNGVALPVDGRMYAR---GHILFIAESLTRD-SGVYICEATNIAGSKQAKSE 297 Query: 2732 IKI 2734 +K+ Sbjct: 298 LKV 300 Score = 39.5 bits (88), Expect = 0.065 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 4/81 (4%) Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557 + L E PV L +A G P P + W K G ++ + H L + +A D Sbjct: 14 ANLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLVS----KGHEIVAGGRLFLGKATLGD 69 Query: 558 AAWYQCTAQNVAGSTATRARL 578 + Y+CTA + G + ++ L Sbjct: 70 SGEYECTATSPLGYVSAKSNL 90 Score = 39.5 bits (88), Expect = 0.065 Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 6/112 (5%) Query: 647 TAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDS 706 TA +I F E G P I W KNG ++ R ++ G+I SL +DS Sbjct: 223 TARTLTRIIFNITCETEGLPAPNITWKKNGVALPVDGR---MYARGHILFIAESLT-RDS 278 Query: 707 GEYTCRAVSATGVAETKAVLHVTP--RATIERTSQHPETLQYIQQLEDYSKY 756 G Y C A + G + K+ L V I T Q E L+ + + Y Sbjct: 279 GVYICEATNIAGSKQAKSELKVIAPVEPVITATVQRLEELRPVSITTEVGSY 330 Score = 39.5 bits (88), Expect = 0.065 Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 31/192 (16%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P+ K+ W+K+G TL + L++ +L DSG+Y C+A NL G + + Sbjct: 452 PSPKLSWYKDGETLNVSHAV----------LTLPTLSPSDSGLYRCEARNLKGVDDADSY 501 Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791 + + L+G P S+ + ++++ N+ Sbjct: 502 LTV-----LVGS---PPSI---------RTTSENITETENIAYIVTGIGSDVITLLSSNV 544 Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851 C V P I W + +PL K + +L + E +G+Y C AT Sbjct: 545 EVTCPVRGF--PLPSITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVAT 600 Query: 2852 NSKGSATTSGSL 2863 NS G+AT + +L Sbjct: 601 NSLGAATATTTL 612 Score = 39.1 bits (87), Expect = 0.086 Identities = 78/352 (22%), Positives = 137/352 (38%), Gaps = 73/352 (20%) Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 + W NG + R+ G++ L IA DSGVY A N AG Q + + V Sbjct: 246 ITWKKNGVALPVDGRMYAR---GHI-LFIAESLTRDSGVYICEATNIAGSKQAKSELKVI 301 Query: 1137 TR-SSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195 + T+++ R +EE + P+ E+ +++ L E N+ Sbjct: 302 APVEPVITATVQR--------LEE---LRPVSITTEVGS----YIRTL-------ETSNL 339 Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255 L C + G P + W G+++ Y I +A DTG YT A Sbjct: 340 TLVCTVR--GFPLPVISWRRGGQAINNTQSALRYR--------IENARVKDTGIYTCVAR 389 Query: 1256 NHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSR 1315 N +G ++S+ + ++ + T +TV++ + S Sbjct: 390 NLVGYDYSSSNISIVAAKPPIIRTSTHH---------------------LTVLRRDKIST 428 Query: 1316 AL-HNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374 L N+ T+ G V L C G + ++ W+ +G+ + H L L + Sbjct: 429 DLGKNVTTLSGNTVSLLCNA--TGVPSPKLSWYKDGETLNVSH----------AVLTLPT 476 Query: 1375 VYPEDSGVYTCQATNQLG--EAVTSCALRVIAKKDLILESQHPSGLEKIQYL 1424 + P DSG+Y C+A N G +A + + V + + S++ + E I Y+ Sbjct: 477 LSPSDSGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTTSENITETENIAYI 528 Score = 38.7 bits (86), Expect = 0.11 Identities = 30/132 (22%), Positives = 56/132 (42%), Gaps = 8/132 (6%) Query: 1466 CKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525 C+ E + N + W KNG + + R ++ G++ L I + + DSG+Y C A N+ Sbjct: 236 CETEGLPAPN--ITWKKNGVALPVDGR---MYARGHI-LFIAESLTRDSGVYICEATNIA 289 Query: 1526 GTDEVSCRLTCRSTTD--IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTS 1583 G+ + L + + I + Q L + + + Y RT +T + Sbjct: 290 GSKQAKSELKVIAPVEPVITATVQRLEELRPVSITTEVGSYIRTLETSNLTLVCTVRGFP 349 Query: 1584 LKNVEIKEGQRA 1595 L + + G +A Sbjct: 350 LPVISWRRGGQA 361 Score = 37.9 bits (84), Expect = 0.20 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 4/80 (5%) Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338 E A + +G P P V W K G++L+ S HEI+ L + DSG Y Sbjct: 20 EKAPVTLTCKATGLPLPTVRWIKGGRQLV-SKGHEIVAGGR---LFLGKATLGDSGEYEC 75 Query: 339 LAENPNGCIVTSGYLAVESP 358 A +P G + L ++ P Sbjct: 76 TATSPLGYVSAKSNLEIKVP 95 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 4/63 (6%) Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575 G P P ITW+K+GV + + R++ G L I + D+ Y C A N+AGS + Sbjct: 240 GLPAPNITWKKNGVALPVDG--RMYARG--HILFIAESLTRDSGVYICEATNIAGSKQAK 295 Query: 576 ARL 578 + L Sbjct: 296 SEL 298 Score = 37.5 bits (83), Expect = 0.26 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 5/95 (5%) Query: 388 KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447 K L P V + + E C+ TG P P V W RQ+ H+I+ +G Sbjct: 3 KNLEPVSVLIGANLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLVSK-GHEIV---AGG 58 Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 L + TL DSG C A + G + + L + Sbjct: 59 R-LFLGKATLGDSGEYECTATSPLGYVSAKSNLEI 92 Score = 36.7 bits (81), Expect = 0.46 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 2/57 (3%) Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001 I W +G+ L+Q K+ + G TL L+ + ER +G+Y C A N G A ++T+ Sbjct: 558 ITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATATTTL 612 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721 +E R P I W K+G L +K G TL + S+ +G+Y C ATN Sbjct: 544 VEVTCPVRGFPLPSITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATN 601 Query: 2722 LLGEAVSTASIKI 2734 LG A +T ++ + Sbjct: 602 SLGAATATTTLNV 614 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 2/63 (3%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 G P I W +G+P V N G L + I R AG Y C ATN G+AT T Sbjct: 552 GFPLPSITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATAT 609 Query: 3783 AKI 3785 + Sbjct: 610 TTL 612 Score = 35.5 bits (78), Expect = 1.1 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774 F+ E G P I W NG R++ FIA + RD+G Y C ATN Sbjct: 232 FNITCETEGLPAPNITWKKNGVALPVDGRMYARGHILFIAESL----TRDSGVYICEATN 287 Query: 3775 KWGSATTTAKITCSAKRDIVL 3795 GS +++ A + V+ Sbjct: 288 IAGSKQAKSELKVIAPVEPVI 308 Score = 35.1 bits (77), Expect = 1.4 Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 4/83 (4%) Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788 ++ +E P + T PT++W++ G + + +++ G L +G D+ Sbjct: 15 NLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLV-SKGHEIVAGGR---LFLGKATLGDS 70 Query: 4789 GTFTCRATTAAGQVETSAKLVVK 4811 G + C AT+ G V + L +K Sbjct: 71 GEYECTATSPLGYVSAKSNLEIK 93 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 6/75 (8%) Query: 2791 IHFECNVEPSRDPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCK 2849 I F E P I W N LP G Y H L I + DSG+Y C+ Sbjct: 230 IIFNITCETEGLPAPNITWKKNGVALPVDGRMYARGH-----ILFIAESLTRDSGVYICE 284 Query: 2850 ATNSKGSATTSGSLR 2864 ATN GS L+ Sbjct: 285 ATNIAGSKQAKSELK 299 Score = 35.1 bits (77), Expect = 1.4 Identities = 71/322 (22%), Positives = 122/322 (37%), Gaps = 69/322 (21%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595 G P+ W NGV L + R F+ + D+G+Y+C+A N AG Sbjct: 240 GLPAPNITWKKNGVALPVDGRMYARGHILFIAESLT----RDSGVYICEATNIAGSKQAK 295 Query: 2596 XXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPI-FTTHLKSYDKL 2654 + + P + A + ++ E+ P+ TT + SY + Sbjct: 296 SELK-------VIAPVEP-------VITATVQRLEEL--------RPVSITTEVGSYIRT 333 Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714 +E ++ L V R P I W + G + +S + I + R D+GI Sbjct: 334 LETSNLTLVCTV--RGFPLPVISWRRGGQAINN---TQSALRY-----RIENARVKDTGI 383 Query: 2715 YTCKATNLLGEAVSTASIKI-EDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXX 2773 YTC A NL+G S+++I I + ++ S H ++ R + Sbjct: 384 YTCVARNLVGYDYSSSNISIVAAKPPIIRTSTHHLTVLRRDKISTDLG------------ 431 Query: 2774 XVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSL 2833 N+ G+ + CN + P+ K+ W+ + + L + S+ L Sbjct: 432 -------KNVTTLSGNTVSLLCNA--TGVPSPKLSWYKDGETL----------NVSHAVL 472 Query: 2834 DITHTYEEDSGIYTCKATNSKG 2855 + DSG+Y C+A N KG Sbjct: 473 TLPTLSPSDSGLYRCEARNLKG 494 Score = 34.7 bits (76), Expect = 1.9 Identities = 35/132 (26%), Positives = 49/132 (37%), Gaps = 4/132 (3%) Query: 3788 SAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGV 3847 SA+R + L LP + + S +E I S + + T + Sbjct: 171 SAERSLHLPDILPNALLSARHSAEPPIPPSIKTSDEIIESLKRDPLGLVIGQTARTLTRI 230 Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907 F E + P I W +NG LP R +Y G + L I DSG YIC A Sbjct: 231 IFNITCETEGLPAPNITWKKNGVALPVDGR---MYARGHI-LFIAESLTRDSGVYICEAT 286 Query: 3908 NDFGEDFTKATI 3919 N G K+ + Sbjct: 287 NIAGSKQAKSEL 298 Score = 34.7 bits (76), Expect = 1.9 Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 6/101 (5%) Query: 3312 PDLKVEWFYNGKKLP-HGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370 P + W NG LP G Y H IL I +SG Y C ATN G K+ Sbjct: 242 PAPNITWKKNGVALPVDGRMYARGH-----ILFIAESLTRDSGVYICEATNIAGSKQAKS 296 Query: 3371 NLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTS 3411 LK + ++ + + R E + T S +R +TS Sbjct: 297 ELKVIAPVEPVITATVQRLEELRPVSITTEVGSYIRTLETS 337 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 7/81 (8%) Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141 I W NG + R+ YA G ++ I + T DSG Y C ATN G + +L+ + Sbjct: 246 ITWKKNGVALPVDGRM---YARGHILF-IAESLTRDSGVYICEATNIAGSKQAKSELKVI 301 Query: 3142 DKSKGQKPRFTTHIQNIEGLK 3162 +P T +Q +E L+ Sbjct: 302 ---APVEPVITATVQRLEELR 319 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G P + W+K G+ + + I G + L +L DSGEY C A S G K Sbjct: 32 GLPLPTVRWIKGGRQLVSKGH--EIVAGGRLFLGKATLG--DSGEYECTATSPLGYVSAK 87 Query: 724 AVLHV 728 + L + Sbjct: 88 SNLEI 92 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P + W KDG+P+ S +T N +L ++ + AG Y A N LG A +T + Sbjct: 554 PLPSITWLKDGQPLKQS--MTVKVNNLTGTLYLLSILERRAGLYMCVATNSLGAATATTT 611 Query: 860 IRV 862 + V Sbjct: 612 LNV 614 Score = 33.1 bits (72), Expect = 5.7 Identities = 14/23 (60%), Positives = 18/23 (78%) Query: 3351 NSGEYECVATNKLGRDSTKANLK 3373 +SGEYEC AT+ LG S K+NL+ Sbjct: 69 DSGEYECTATSPLGYVSAKSNLE 91 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 12/85 (14%) Query: 644 KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI 703 K+VT + G + G P+ K+ W K+G+++ S + L + +L+ Sbjct: 432 KNVTTLSGNTVSL--LCNATGVPSPKLSWYKDGETLNVS----------HAVLTLPTLSP 479 Query: 704 QDSGEYTCRAVSATGVAETKAVLHV 728 DSG Y C A + GV + + L V Sbjct: 480 SDSGLYRCEARNLKGVDDADSYLTV 504 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 4/99 (4%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 P L N+ V L K TG V W+K G+++ +K E L + Sbjct: 7 PVSVLIGANLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLV----SKGHEIVAGGRLFL 62 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612 +A DSG+YEC A + G + + +P + P Sbjct: 63 GKATLGDSGEYECTATSPLGYVSAKSNLEIKVPFSFHHP 101 Score = 32.7 bits (71), Expect = 7.5 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 8/72 (11%) Query: 2131 CRVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNK 2189 C E + P++T W NG + G Y H L I + DSG Y+C+ATN Sbjct: 236 CETEGLPAPNIT--WKKNGVALPVDGRMYARGH-----ILFIAESLTRDSGVYICEATNI 288 Query: 2190 LGEAVNTCTLKV 2201 G LKV Sbjct: 289 AGSKQAKSELKV 300 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 10/59 (16%) Query: 95 LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 +RG P PV+SW R+ + + ++RY + V D G YTC ARN G Sbjct: 345 VRGFPLPVISW-RRGGQAINNTQSALRYRIENARVK---------DTGIYTCVARNLVG 393 Score = 32.3 bits (70), Expect = 9.9 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 8/105 (7%) Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019 T D++ + K+ P V Q+ +L + C+ + PN + W NG L Sbjct: 203 TSDEIIESLKRDPLGLVIG-QTARTLTRI-IFNITCETEGLPAPN--ITWKKNGVALPVD 258 Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064 R +Y G++ DSG Y+C ATN+ G + K+ +K Sbjct: 259 GR---MYARGHILF-IAESLTRDSGVYICEATNIAGSKQAKSELK 299 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Query: 88 NAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCT 147 N + +RG P P ++W + PL + +++ N TG + LL I G Y C Sbjct: 543 NVEVTCPVRGFPLPSITWLKDGQPLKQ--SMTVKVNNLTGTLYLL--SILERRAGLYMCV 598 Query: 148 ARNQYGEA 155 A N G A Sbjct: 599 ATNSLGAA 606 >SB_52575| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1267 Score = 69.3 bits (162), Expect = 7e-11 Identities = 79/316 (25%), Positives = 134/316 (42%), Gaps = 42/316 (13%) Query: 4503 KRRQGRGGIV--PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN 4560 K +G GI P+ T +++ +G+ + L G + W + + P R+ Sbjct: 247 KGEKGDAGISVRAPTITQPPKSLITIAGETIFLTCSSEGLPSPKIDWGRVSGTL-PSGRH 305 Query: 4561 KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAAN 4620 ++ +GT L L + D G Y CVA N G+AR A V +P + A+ Sbjct: 306 -VVHSNGTLALTQLRS--GDEGLYACVAKNVLGKARAFASVGVLVPI---------QMAH 353 Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680 P +D++V + + +C+ G P P WY+ ++++ + T+D + Sbjct: 354 KP-------EDQVVQDNSTVMLNCQATGFPDPNYTWYRNNQVL-------TTLTSDNGSF 399 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740 I++A +D G Y C A N V AKL V + LTP + + G Sbjct: 400 IITKATADDSGVYVCAAKNMLNEVRATAKLIVARLLSF----TLTPPAVLQAHAGAKVIL 455 Query: 4741 KTQITS-KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799 Q S + P I+WLR G + + +H +N L + T D GT+ C A Sbjct: 456 NCQADSGLLVPRIKWLRAGKHVTDG-----VH--SNGSLEVNVTSLADEGTYACVAENDV 508 Query: 4800 G-QVETSAKLVVKSKT 4814 G ++ +S ++ V +T Sbjct: 509 GAKINSSCEVKVYFRT 524 Score = 63.3 bits (147), Expect = 5e-09 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%) Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458 +D+ V + +C+ TG P P TW+ N N + S N + +IT T Sbjct: 356 EDQVVQDNSTVMLNCQATGFPDPNYTWYRN--------NQVLTTLTSDNGSFIITKATAD 407 Query: 459 DSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVREGEPVVLNARA-VG 516 DSGV C A+N E +L V + P V L G V+LN +A G Sbjct: 408 DSGVYVCAAKNMLNEVRATAKLIVARLLSFTLTPPAV-----LQAHAGAKVILNCQADSG 462 Query: 517 TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 PRI W + G + +H++G +L++ +D Y C A+N G+ Sbjct: 463 LLVPRIKWLRAGKHVTDG----VHSNG---SLEVNVTSLADEGTYACVAENDVGA 510 Score = 54.0 bits (124), Expect = 3e-06 Identities = 64/279 (22%), Positives = 113/279 (40%), Gaps = 43/279 (15%) Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494 +G P P I W R + + + H + L + Q+ D ++A VA+N G A+ Sbjct: 284 EGLPSPKIDWGRVSGTLPSGR----HVVHSNGTLALTQLRSGDEGLYACVAKNVLGKARA 339 Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554 A++ G +VP ++ V V L+ + TG + W +N + Sbjct: 340 FASV----------GVLVPIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYTWYRNNQ-- 387 Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614 + + ++G++ +I +A DSG Y C A N E R A+ +V+ + P Sbjct: 388 ---VLTTLTSDNGSF--IITKATADDSGVYVCAAKNMLNEVRATAKLIVARLLSFTLTPP 442 Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674 A+A K++ QA G +P ++W + K + + S Sbjct: 443 AVLQAHAGA--------KVILNCQADS------GLLVPRIKWLRAGKHVTDGVHSNGS-- 486 Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAG-RVTVAAKLKV 4712 L ++ DEG Y CVA N G ++ + ++KV Sbjct: 487 -----LEVNVTSLADEGTYACVAENDVGAKINSSCEVKV 520 Score = 52.0 bits (119), Expect = 1e-05 Identities = 47/173 (27%), Positives = 76/173 (43%), Gaps = 17/173 (9%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 G+ C G P P++ W R + + +V+ +G AL T + D G+ C Sbjct: 274 GETIFLTCSSEGLPSPKIDW---GRVSGTLPSGRHVVHSNGTLAL--TQLRSGDEGLYAC 328 Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525 VA+N G+ + V+ Q +A K ++ V++ V+LN +A G P P TW Sbjct: 329 VAKNVLGKARAFASVGVLVPIQ-MAHKPEDQV----VQDNSTVMLNCQATGFPDPNYTWY 383 Query: 526 KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 ++ N L T S + I +A A D+ Y C A+N+ A+L Sbjct: 384 RN------NQVLTTLTSDNGSFI-ITKATADDSGVYVCAAKNMLNEVRATAKL 429 Score = 46.4 bits (105), Expect = 6e-04 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 8/101 (7%) Query: 2635 DTGVQ-QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693 D G+ +AP T KS + G+ ++L E P KI+W + TL +G + Sbjct: 252 DAGISVRAPTITQPPKSLITIA-GETIFLTCSSEGLPSP--KIDWGRVSGTLPSGRHVVH 308 Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 + TL++ LR+ D G+Y C A N+LG+A + AS+ + Sbjct: 309 SNG----TLALTQLRSGDEGLYACVAKNVLGKARAFASVGV 345 Score = 44.0 bits (99), Expect = 0.003 Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 12/101 (11%) Query: 2633 FVDTGVQQAPIFTTHLKSYDKLVEGQH-VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691 F GV PI H K D++V+ V L Q DPN W++N LTT Sbjct: 340 FASVGVL-VPIQMAH-KPEDQVVQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT---- 391 Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732 T D G + I DDSG+Y C A N+L E +TA + Sbjct: 392 -LTSDNG--SFIITKATADDSGVYVCAAKNMLNEVRATAKL 429 Score = 43.2 bits (97), Expect = 0.005 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 7/84 (8%) Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318 S+G + P ++A KP + +Q+ + Q +G P P TW++N Q L +T+ Sbjct: 342 SVGVLVPIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYTWYRNNQVLTT------LTSD 395 Query: 319 NHTTLRVRNTQKSDSGHYTLLAEN 342 N + + + T DSG Y A+N Sbjct: 396 NGSFIITKAT-ADDSGVYVCAAKN 418 Score = 42.7 bits (96), Expect = 0.007 Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 5/103 (4%) Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527 R + GET F+ V AP + +L GE + L + G P+P+I W + Sbjct: 238 RGERGETGFKGEKGDAGIS-VRAPTITQPPKSLITIAGETIFLTCSSEGLPSPKIDWGRV 296 Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 +P+ +H++G TL + + ++ D Y C A+NV G Sbjct: 297 S-GTLPSGRHVVHSNG---TLALTQLRSGDEGLYACVAKNVLG 335 Score = 41.5 bits (93), Expect = 0.016 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 7/98 (7%) Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421 FK + ++ + P TQP +++ I G+T C G P+ K++W R + Sbjct: 246 FKGEKGDAGISVRAPTITQPPKSLITIA-GETIFLTCS--SEGLPSPKIDWGRVSGTLPS 302 Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 + H G +++T +R DEG+Y C A N+LG+ Sbjct: 303 GRHVV--HSNGTLALT--QLRSGDEGLYACVAKNVLGK 336 Score = 39.9 bits (89), Expect = 0.049 Identities = 51/193 (26%), Positives = 76/193 (39%), Gaps = 24/193 (12%) Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105 R P T K ++ I+ G+ S G S I+W T+ + + V++ G Sbjct: 258 RAPTITQPPKSLITIA-GETIFLTCS--SEGLPSPKIDWGRVSGTLPSGRHV--VHSNGT 312 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165 + L L ++ D G Y+C A N G+A + + P H + ++D Sbjct: 313 LALTQL--RSGDEGLYACVAKNVLGKARAFASVGVL------VPIQMAHKPEDQVVQDNS 364 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 + C DP+ WY N Q + T SD G ++ A DSG YVC Sbjct: 365 TVMLNCQATGFPDPNYT--WYRNNQVLTTLT-----SDNGSFIITKATAD--DSGVYVCA 415 Query: 3226 AYNKYGEDFTRAT 3238 A N E RAT Sbjct: 416 AKNMLNE--VRAT 426 Score = 38.7 bits (86), Expect = 0.11 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 9/72 (12%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 +Q+ T +C+ DP W+RN +++ T T D G S I+ +D G Sbjct: 360 VQDNSTVMLNCQATGFPDPNYT--WYRNNQVLT-----TLTSDNG--SFIITKATADDSG 410 Query: 2448 VYMCRASNLLGE 2459 VY+C A N+L E Sbjct: 411 VYVCAAKNMLNE 422 Score = 38.3 bits (85), Expect = 0.15 Identities = 57/257 (22%), Positives = 90/257 (35%), Gaps = 30/257 (11%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA- 155 G P+P + W R L ++ + N +L + Q+ GDEG Y C A+N G+A Sbjct: 285 GLPSPKIDWGRVSGTLPS-GRHVVHSNG-----TLALTQLRSGDEGLYACVAKNVLGKAR 338 Query: 156 -ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214 SV + V + + YT ++ Q ++ Sbjct: 339 AFASVGVLVPIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYTWYRNNQVLTTLTSDNGS 398 Query: 215 HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLG-PVSPPKIAQKPR 273 T D+ Y K + E + R L ++PP + Q Sbjct: 399 FIITKATADDSGVY---------VCAAKNMLNEVRATAKLIVARLLSFTLTPPAVLQAHA 449 Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 +K+ A SG PR+ W + G KH H++ +L V T +D Sbjct: 450 GAKVILNCQAD-----SGLLVPRIKWLRAG-------KHVTDGVHSNGSLEVNVTSLADE 497 Query: 334 GHYTLLAENPNGCIVTS 350 G Y +AEN G + S Sbjct: 498 GTYACVAENDVGAKINS 514 Score = 35.5 bits (78), Expect = 1.1 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 9/116 (7%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 P + P D ++ +NS+ C+ D + W+ N + L T T ++ F+I Sbjct: 348 PIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT----LTSDNGSFII 401 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672 + D+G+Y C A N E + KL V L P +G + I Sbjct: 402 TKATA---DDSGVYVCAAKNMLNEVRATAKLIVARLLSFTLTPPAVLQAHAGAKVI 454 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 9/81 (11%) Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915 + + + C+ +PDPN WY N +VL + TS++ F I +DSG Sbjct: 360 VQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT----LTSDNGSFI---ITKATADDSG 410 Query: 1916 EYTCKAINNLGQAVSSIRLNV 1936 Y C A N L + ++ +L V Sbjct: 411 VYVCAAKNMLNEVRATAKLIV 431 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 6/90 (6%) Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496 D ++++ +T+P I G+ + C E + K++W + + G + Sbjct: 252 DAGISVRAPTITQPPKSLITIAGETIFLTCSSEGLPSP--KIDWGRVSGTLPSGRHV--V 307 Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526 H G +AL L + D G+Y C A N++G Sbjct: 308 HSNGTLALT--QLRSGDEGLYACVAKNVLG 335 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 9/82 (10%) Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180 +++ C+ DP+ T W+ N Q + T D G + I A+DSG Sbjct: 360 VQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT-----LTSDNG--SFIITKATADDSG 410 Query: 2181 TYMCKATNKLGEAVNTCTLKVA 2202 Y+C A N L E T L VA Sbjct: 411 VYVCAAKNMLNEVRATAKLIVA 432 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 6/82 (7%) Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841 +++ G+ I C+ E P KI+W + LPSG ++ +L +T Sbjct: 268 SLITIAGETIFLTCSSEGLPSP--KIDWGRVSGTLPSGRHVVHSNG----TLALTQLRSG 321 Query: 2842 DSGIYTCKATNSKGSATTSGSL 2863 D G+Y C A N G A S+ Sbjct: 322 DEGLYACVAKNVLGKARAFASV 343 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 9/87 (10%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885 V P + + + V+++ V C+ DP WYRN ++L + D G Sbjct: 345 VLVPIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT-----LTSDNG 397 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGE 3912 S I A+DSG Y+C A N E Sbjct: 398 --SFIITKATADDSGVYVCAAKNMLNE 422 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 4/83 (4%) Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 V P I Q P++ G G P P++ W + L S +H + H++ T Sbjct: 257 VRAPTITQPPKSLITIAGETIFLTCSSEGLPSPKIDWGRVSGTL-PSGRHVV---HSNGT 312 Query: 323 LRVRNTQKSDSGHYTLLAENPNG 345 L + + D G Y +A+N G Sbjct: 313 LALTQLRSGDEGLYACVAKNVLG 335 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 4/52 (7%) Query: 2152 IRAG-HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVN-TCTLKV 2201 +RAG H H G +L++ T D GTY C A N +G +N +C +KV Sbjct: 471 LRAGKHVTDGVHSNG--SLEVNVTSLADEGTYACVAENDVGAKINSSCEVKV 520 >SB_41626| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 753 Score = 69.3 bits (162), Expect = 7e-11 Identities = 77/320 (24%), Positives = 124/320 (38%), Gaps = 46/320 (14%) Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL----IL 4574 + V + G + L+ K +D+ W + ++ P R + +E+D Y ++ I+ Sbjct: 9 SNKVTLDEGSTLTLECKANIDDFLDIGWERKDQRTLPSNRTVLDVEDDDGYFIIKRLSIV 68 Query: 4575 EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV 4634 + P D+G Y C A D E V+ + PQ AN ++ Sbjct: 69 DMLPSDAGVYTCQGWTYNSSAPSDVEVKVN-----EFVSPQVSLANL----------SVI 113 Query: 4635 AEGQAIEFSCKIV-GKPLPTVQWYK-GDKLIK------------PSKYFQMSRTADEYT- 4679 + + +E C+I+ G P P V WYK G L P+ + A YT Sbjct: 114 SSQKQVELKCQILAGYPTPQVSWYKDGTPLTPKPLGPRRNCTSFPTGVYYYDEYAPPYTR 173 Query: 4680 --LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737 + + F + G Y C A N R L V + + P DI++ G+ Sbjct: 174 VLVLCNPRFLQSTGWYTCGAENVRNRTRDTKYLNVFESPTV----TIDPNHDIIINIGES 229 Query: 4738 AQFKTQITSKIKPTIQWLRE---GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794 + + T P + WL E G ++P P EG + V++ E D G +TC Sbjct: 230 LELRCFATGNPTPEVIWLHELENGEVVPVDPGHVFSVEG-SLVVIKPRIEENDYGPYTCH 288 Query: 4795 ATTAAGQVETSAKLVVKSKT 4814 A+ G SA LV+ T Sbjct: 289 ASNRHGNTTKSA-LVLSGTT 307 Score = 46.4 bits (105), Expect = 6e-04 Identities = 35/141 (24%), Positives = 55/141 (39%), Gaps = 6/141 (4%) Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516 L +G TC A N T LNV E V ++ + + GE + L A G Sbjct: 183 LQSTGWYTCGAENVRNRTRDTKYLNVFESPTVT----IDPNHDIIINIGESLELRCFATG 238 Query: 517 TPTPRITW--QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574 PTP + W + + ++P + + G+ + PR + +D Y C A N G+T Sbjct: 239 NPTPEVIWLHELENGEVVPVDPGHVFSVEGSLVVIKPRIEENDYGPYTCHASNRHGNTTK 298 Query: 575 RARLYXXXXXXXXXXQKRLHL 595 A + + HL Sbjct: 299 SALVLSGTTLAKKKVPDKPHL 319 Score = 44.0 bits (99), Expect = 0.003 Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 13/148 (8%) Query: 396 KVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH----A 449 K+ VT EG +C+ + ++ W D++ + V + + Sbjct: 5 KITPSNKVTLDEGSTLTLECKANIDDFLDIGWERKDQRTLPSNRTVLDVEDDDGYFIIKR 64 Query: 450 LMITNVTLSDSGVVTCVA--RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507 L I ++ SD+GV TC N S + + ++N QV + S ++ ++ Sbjct: 65 LSIVDMLPSDAGVYTCQGWTYNSSAPSDVEVKVNEFVSPQVS----LANLSVISSQKQVE 120 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNP 535 + A G PTP+++W KDG P+ P P Sbjct: 121 LKCQILA-GYPTPQVSWYKDGTPLTPKP 147 Score = 37.1 bits (82), Expect = 0.35 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 4/91 (4%) Query: 3698 TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH---NGRPFATGSRVHTLNDFGFIA 3754 TV I N D+ + R G+PT + W H NG H + G + Sbjct: 213 TVTIDPNHDIIINIGESLELRCFATGNPTPEVIWLHELENGEVVPVDPG-HVFSVEGSLV 271 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 + I D G YTC A+N+ G+ T +A + Sbjct: 272 VIKPRIEENDYGPYTCHASNRHGNTTKSALV 302 Score = 34.7 bits (76), Expect = 1.9 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 9/92 (9%) Query: 3558 PEFTTTPS-DLILSENSSAHFECRLIPVNDSSMRVEWFH---NGKPL-LTGSRVKTINDF 3612 P T P+ D+I++ S C + + V W H NG+ + + V ++ Sbjct: 212 PTVTIDPNHDIIINIGESLELRC--FATGNPTPEVIWLHELENGEVVPVDPGHVFSVE-- 267 Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVS 3644 G +++ + + D G YTC A+NRHG T S Sbjct: 268 GSLVVIKPRIEENDYGPYTCHASNRHGNTTKS 299 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 5/72 (6%) Query: 406 GKMTRFDCRVTGRPYPEVTW---FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 G+ C TG P PEV W N + D H V G+ ++ + +D G Sbjct: 227 GESLELRCFATGNPTPEVIWLHELENGEVVPVDPGHVFSV--EGSLVVIKPRIEENDYGP 284 Query: 463 VTCVARNKSGET 474 TC A N+ G T Sbjct: 285 YTCHASNRHGNT 296 Score = 32.7 bits (71), Expect = 7.5 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 9/83 (10%) Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR--FRPIHDFG 1500 KP+ P + + EG + ECK D L + W + Q +R D G Sbjct: 3 KPKIT--PSNKVTLDEGSTLTLECKAN--IDDFLDIGWERKDQRTLPSNRTVLDVEDDDG 58 Query: 1501 YVA---LDIIDLIAEDSGIYTCR 1520 Y L I+D++ D+G+YTC+ Sbjct: 59 YFIIKRLSIVDMLPSDAGVYTCQ 81 >SB_53570| Best HMM Match : Y_phosphatase (HMM E-Value=0) Length = 2064 Score = 68.9 bits (161), Expect = 9e-11 Identities = 53/175 (30%), Positives = 73/175 (41%), Gaps = 11/175 (6%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C VTG P P +TW+ N IR+ + G + + + C A N G Sbjct: 91 CNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRIGPLRAKIHKA-TYECEADNGVG 149 Query: 473 ETAFQCRLNVIEKEQVVA---PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529 ++ P+ + S R G+ V AVGTPTP ITW KD + Sbjct: 150 PPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRL 209 Query: 530 PIIPN-PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG----STATRARLY 579 PI+ N P + + +DG L I + SD Y C A+N G S A ARL+ Sbjct: 210 PIVLNDPRVSVLSDG--RKLRITDLRESDNGKYSCVARNALGMVFSSQAMPARLF 262 Score = 67.7 bits (158), Expect = 2e-10 Identities = 81/304 (26%), Positives = 127/304 (41%), Gaps = 31/304 (10%) Query: 4514 PSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD-IRNKILEEDGTYTL 4571 P+ TLT ++ VT G V + VTG+ + W KNG ++ I+ + G + Sbjct: 70 PTVTLTPKDFAGVTRG-FVYMICNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRI 128 Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631 L A + YEC A N G D+ ++ A+ TK A P I + Sbjct: 129 GPLRAKIHKA-TYECEADNGVGPPLRDSSTLIVHTAS-------TKPAGFP-RIAKHPSF 179 Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691 K G + F+C VG P P + W+K D+L ++S +D LRI++ D G Sbjct: 180 KQRRSGDDVTFTCAAVGTPTPNITWFK-DRLPIVLNDPRVSVLSDGRKLRITDLRESDNG 238 Query: 4692 DYKCVAYNSAGRV----TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747 Y CVA N+ G V + A+L + L P +D V + K Sbjct: 239 KYSCVARNALGMVFSSQAMPARLFIVVVRSKPEF-TLRP-QDKTVDPDTDVELKCSARGS 296 Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807 P+I W +G+ I G N L+I + +G ++C A + G+V+ A Sbjct: 297 PTPSIVWEVDGSRI----------SGQNGELIIRGI--QRSGNYSCIADSNMGRVQAYAY 344 Query: 4808 LVVK 4811 + V+ Sbjct: 345 VTVR 348 Score = 62.1 bits (144), Expect = 1e-08 Identities = 74/273 (27%), Positives = 110/273 (40%), Gaps = 37/273 (13%) Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321 P P + P++ ++G+P P +TW+KNG +I +++ +I T Sbjct: 66 PYQTPTVTLTPKDFAGVTRGFVYMICNVTGSPMPTLTWYKNGS-VIRNSRIQIFTMPYGG 124 Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381 +R+ ++ T E NG V P ++D S I T + Sbjct: 125 LIRI-GPLRAKIHKATYECEADNG---------VGPP----LRDS-STLIVHTASTKPAG 169 Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ--IRDDYNHK 439 I++ P F + DVT F C G P P +TWF DR + +D Sbjct: 170 FPRIAKH---PSFKQRRSGDDVT------FTCAAVGTPTPNITWF-KDRLPIVLNDPRVS 219 Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSG----ETAFQCRLNVIEKEQVVAPKFVE 495 +L S L IT++ SD+G +CVARN G A RL ++ P+F Sbjct: 220 VL---SDGRKLRITDLRESDNGKYSCVARNALGMVFSSQAMPARLFIVVVRS--KPEFTL 274 Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528 R V V L A G+PTP I W+ DG Sbjct: 275 RPQDKTVDPDTDVELKCSARGSPTPSIVWEVDG 307 Score = 56.8 bits (131), Expect = 4e-07 Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 29/193 (15%) Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318 S P P+IA+ P + + G D F G P P +TWFK+ ++ N + Sbjct: 164 STKPAGFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIV-LNDPRVSVLS 222 Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378 + LR+ + ++SD+G Y+ +A N G + +S + P ++ RS+ Sbjct: 223 DGRKLRITDLRESDNGKYSCVARNALGMVFSSQAM----PARLFIVVVRSK--------- 269 Query: 379 TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438 P+F QD+ V C G P P + W ++ +I Sbjct: 270 -------------PEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRISGQNGE 316 Query: 439 KIL--VNESGNHA 449 I+ + SGN++ Sbjct: 317 LIIRGIQRSGNYS 329 Score = 54.0 bits (124), Expect = 3e-06 Identities = 70/280 (25%), Positives = 108/280 (38%), Gaps = 30/280 (10%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE-DSAVFAAVAENR-GGTAK 4493 G P+P + WY+ I+NS QI T ++ I + + A + A+N G + Sbjct: 95 GSPMPTLTWYKNGSVIRNS-RIQIFTMPYGGLIRIGPLRAKIHKATYECEADNGVGPPLR 153 Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553 S+ L+V + G P SG V GT ++ W K+ Sbjct: 154 DSSTLIVHTASTKPAGF---PRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLP 210 Query: 4554 -VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612 V D R +L DG L I + D+GKY CVA N+ G ++PA Sbjct: 211 IVLNDPRVSVL-SDGR-KLRITDLRESDNGKYSCVARNALGMVFSSQ----AMPA----- 259 Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672 + + PE +DK V +E C G P P++ W ++S Sbjct: 260 RLFIVVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGS--------RIS 311 Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 E +R + G+Y C+A ++ GRV A + V Sbjct: 312 GQNGELIIRGIQR----SGNYSCIADSNMGRVQAYAYVTV 347 Score = 45.6 bits (103), Expect = 0.001 Identities = 48/193 (24%), Positives = 77/193 (39%), Gaps = 14/193 (7%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASH-RIRTVYAFGMV 3106 P T KD ++ G + Y + TG + W+ NG I S +I T+ G++ Sbjct: 70 PTVTLTPKDFAGVTRGFV--YMICNV-TGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLI 126 Query: 3107 VLEILGTKTTDSGTYSCRATNKWG---QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 + L K TY C A N G + ++ + PR H + + + Sbjct: 127 RIGPLRAKI-HKATYECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKH-PSFKQRRS 184 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPM-RHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222 G F C V P+ I W+ + P+ + R+ +SD L I + D+G+Y Sbjct: 185 GDDVTFTCAAVGTPTPN--ITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNGKY 240 Query: 3223 VCRAYNKYGEDFT 3235 C A N G F+ Sbjct: 241 SCVARNALGMVFS 253 Score = 40.7 bits (91), Expect = 0.028 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 6/91 (6%) Query: 71 PPIFEQIFKNARFAQ---GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127 P F +I K+ F Q G + F G PTP ++W + + P+V + R + + Sbjct: 167 PAGFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIVLNDP---RVSVLSD 223 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158 L I + D G+Y+C ARN G S Sbjct: 224 GRKLRITDLRESDNGKYSCVARNALGMVFSS 254 Score = 39.5 bits (88), Expect = 0.065 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 797 VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856 V PT + W+KD PI + S+ + G L I LR D G Y+ A N LG S Sbjct: 195 VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR-KLRITDLRESDNGKYSCVARNALGMVFS 253 Query: 857 TASI 860 + ++ Sbjct: 254 SQAM 257 Score = 39.5 bits (88), Expect = 0.065 Identities = 45/187 (24%), Positives = 71/187 (37%), Gaps = 17/187 (9%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P P I W+++ PI + D ++ S L I + D+ ++ VA N G S Sbjct: 196 GTPTPNITWFKDRLPIVLN-DPRVSVLSDGRKLRITDLRESDNGKYSCVARNALGMVFSS 254 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555 + R P FTL Q+ V V L G+ + W +G ++ Sbjct: 255 QAMPARLFIVVVRS---KPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRIS 311 Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS-LPATKDKPKP 4614 G LI+ Q SG Y C+A ++ G + A V LP +P Sbjct: 312 -----------GQNGELIIRGI-QRSGNYSCIADSNMGRVQAYAYVTVRLLPFAPSRPNA 359 Query: 4615 QTKAANA 4621 + ++A Sbjct: 360 ASITSDA 366 Score = 36.3 bits (80), Expect = 0.61 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT--DGGASTLDIPRAKASDAAWYQCTA 565 V + G+P P +TW K+G +I N ++I T GG + RAK A Y+C A Sbjct: 87 VYMICNVTGSPMPTLTWYKNG-SVIRNSRIQIFTMPYGGLIRIGPLRAKIHKAT-YECEA 144 Query: 566 QNVAG 570 N G Sbjct: 145 DNGVG 149 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 5/71 (7%) Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNE-KLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 + G F C VG PT + WF++ ++ + R++ D + I+ +R+ D G Sbjct: 183 RSGDDVTFTCAA--VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNG 238 Query: 2448 VYMCRASNLLG 2458 Y C A N LG Sbjct: 239 KYSCVARNALG 249 Score = 35.9 bits (79), Expect = 0.80 Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 12/92 (13%) Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323 S P+ +P++ + D + + G+P P + W +G R+ N E+I Sbjct: 268 SKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRISGQN-GELI-------- 318 Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 +R Q+ SG+Y+ +A++ G + Y+ V Sbjct: 319 -IRGIQR--SGNYSCIADSNMGRVQAYAYVTV 347 Score = 34.7 bits (76), Expect = 1.9 Identities = 30/102 (29%), Positives = 41/102 (40%), Gaps = 4/102 (3%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503 PR P S + G V F C N + WFK+ P+ + + G Sbjct: 171 PRIAKHP-SFKQRRSGDDVTFTCAAVGTPTPN--ITWFKDRLPIVLNDPRVSVLSDGR-K 226 Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRS 1545 L I DL D+G Y+C A N +G S + R +VRS Sbjct: 227 LRITDLRESDNGKYSCVARNALGMVFSSQAMPARLFIVVVRS 268 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P I WFK+ + + S G L I LR D+G Y+C A N LG S+ + Sbjct: 198 PTPNITWFKDRLPIVLNDPRVSVLSDGR-KLRITDLRESDNGKYSCVARNALGMVFSSQA 256 Query: 2732 I 2732 + Sbjct: 257 M 257 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 5/79 (6%) Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLDITHTYEEDSG 2844 + GD++ F C + PT I WF + P+ + R D L IT E D+G Sbjct: 183 RSGDDVTFTCAAVGT--PTPNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNG 238 Query: 2845 IYTCKATNSKGSATTSGSL 2863 Y+C A N+ G +S ++ Sbjct: 239 KYSCVARNALGMVFSSQAM 257 Score = 33.5 bits (73), Expect = 4.3 Identities = 25/69 (36%), Positives = 30/69 (43%), Gaps = 5/69 (7%) Query: 3710 GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTLNDFGFIALDIDYIYARDAGEY 3768 G V F C VG PT I WF + P RV L+D L I + D G+Y Sbjct: 185 GDDVTFTCAA--VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNGKY 240 Query: 3769 TCRATNKWG 3777 +C A N G Sbjct: 241 SCVARNALG 249 Score = 32.7 bits (71), Expect = 7.5 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 936 IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995 +G T + W KD P+ + + + G L I + D G Y+C A NA+G + Sbjct: 195 VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR-KLRITDLRESDNGKYSCVARNALGMVFS 253 Query: 996 S 996 S Sbjct: 254 S 254 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%) Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719 VG PT I W K+ I + S+ G L + L D+G+Y+C A +A G+ Sbjct: 195 VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR-KLRITDLRESDNGKYSCVARNALGM 250 >SB_41623| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1604 Score = 68.9 bits (161), Expect = 9e-11 Identities = 60/205 (29%), Positives = 87/205 (42%), Gaps = 30/205 (14%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP--------DIRNKILE- 4564 P+ L N TS V L VTG P V W K+G+ + P D +N+I E Sbjct: 1014 PTVRLDDLTTNETSS--VALQCHVTGNPPPTVRWYKDGRVLSPRLTLSSLKDCKNRINEL 1071 Query: 4565 -------EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617 + +YTL++ +A DSG YEC A+NS G+ + V +P + + +P Sbjct: 1072 YHLDKRDNEESYTLVVCKASYNDSGSYECQAVNSLGQDKDQGYLDVQVPPSILRIEPDN- 1130 Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677 I +P+K G+ C G P P VQW K + + S Sbjct: 1131 ------FIADPIK-----FGEVFYADCFATGNPTPKVQWKKETENGTFTAVVNSSAQNGH 1179 Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAG 4702 L + +D G+Y+CVA NS G Sbjct: 1180 SRLYFASLREDDLGNYECVAVNSLG 1204 Score = 61.3 bits (142), Expect = 2e-08 Identities = 64/286 (22%), Positives = 113/286 (39%), Gaps = 38/286 (13%) Query: 4538 TGTKPIDV--YWL-KNGKKVQPD----IRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 TG D YW+ K ++++ +R+ + T L ++ A P D+G Y C A Sbjct: 934 TGHSAFDAPPYWVDKENRRIESSGRVSVRSIVRPLQNTTILEVVNASPNDTGHYTCAA-- 991 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650 + + +VS + A +AP ++ L E ++ C + G P Sbjct: 992 ----KKKNNRDIVSTSIFME-----VVAVSAPTVRLDDLTTN---ETSSVALQCHVTGNP 1039 Query: 4651 LPTVQWYKGDKLIKP--------------SKYFQMSRTADE--YTLRISEAFPEDEGDYK 4694 PTV+WYK +++ P ++ + + + +E YTL + +A D G Y+ Sbjct: 1040 PPTVRWYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDNEESYTLVVCKASYNDSGSYE 1099 Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754 C A NS G+ L V P + + D + + G+ T P +QW Sbjct: 1100 CQAVNSLGQDKDQGYLDVQVPPSILRIEPDNFIADPIKF-GEVFYADCFATGNPTPKVQW 1158 Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 +E T + ++ L + E+D G + C A + G Sbjct: 1159 KKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVNSLG 1204 Score = 52.8 bits (121), Expect = 7e-06 Identities = 46/194 (23%), Positives = 74/194 (38%), Gaps = 16/194 (8%) Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDR---------QIRDDYN------HKILVNE 444 D E C VTG P P V W+ + R ++D N H + Sbjct: 1020 DLTTNETSSVALQCHVTGNPPPTVRWYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDN 1079 Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504 ++ L++ + +DSG C A N G+ Q L+V ++ + + F ++ Sbjct: 1080 EESYTLVVCKASYNDSGSYECQAVNSLGQDKDQGYLDVQVPPSILRIE-PDNFIADPIKF 1138 Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 GE + A G PTP++ W+K+ + G S L + D Y+C Sbjct: 1139 GEVFYADCFATGNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECV 1198 Query: 565 AQNVAGSTATRARL 578 A N G+ RL Sbjct: 1199 AVNSLGTKKKIYRL 1212 Score = 50.4 bits (115), Expect = 3e-05 Identities = 52/183 (28%), Positives = 79/183 (43%), Gaps = 32/183 (17%) Query: 422 EVTWFINDRQIRDDYNHKIL-------VNESG----NHALMITNVTLSDSGVVTCVARNK 470 +VTW+ ++R D + KI N +G + L +TNVT D+G C +N+ Sbjct: 601 DVTWY----RVRGDKSEKITKGVQQSETNSNGYLIITNELSLTNVTKEDAGSYMCEKKNR 656 Query: 471 SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530 G TA Q + V + +E+ + + E E + G+P P+I+W + G+P Sbjct: 657 IGATA-QASIYVPVLDTTKPSVNIEK-NNYSAEENEVSRIRCVVSGSPWPKISWYRGGIP 714 Query: 531 II-----PNPELRIHTDGG---------ASTLDIPRA-KASDAAWYQCTAQNVAGSTATR 575 I+ PE G S L+I + D A + C A NVAGST Sbjct: 715 IVTCEGGQFPECPSRFSNGYRASVVKYSYSELEIKNSLYPRDNAMFACVATNVAGSTRDT 774 Query: 576 ARL 578 A L Sbjct: 775 AAL 777 Score = 43.2 bits (97), Expect = 0.005 Identities = 39/137 (28%), Positives = 55/137 (40%), Gaps = 19/137 (13%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L + N + +D+G TC A+ K+ + +E V AP R L E V Sbjct: 974 LEVVNASPNDTGHYTCAAKKKNNRDIVSTSI-FMEVVAVSAPTV--RLDDLTTNETSSVA 1030 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPEL--------RI----HTD----GGASTLDIPRA 553 L G P P + W KDG + P L RI H D + TL + +A Sbjct: 1031 LQCHVTGNPPPTVRWYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDNEESYTLVVCKA 1090 Query: 554 KASDAAWYQCTAQNVAG 570 +D+ Y+C A N G Sbjct: 1091 SYNDSGSYECQAVNSLG 1107 Score = 42.3 bits (95), Expect = 0.009 Identities = 70/321 (21%), Positives = 126/321 (39%), Gaps = 40/321 (12%) Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKILEED-GT 4568 +V P +T ++V G V L V + + V W K+ ++ +++ ++ Sbjct: 118 LVKPRILVTPSQLSVVEGASVTLTCTVQASSQVGAVTWYKDATQLADGVQDYTSDDSLHK 177 Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628 TL + + G YEC NS + +P T+ +I+ Sbjct: 178 NTLRLTNVGKDEGGMYECRVKNSFSYVN----------SYNAEP---TRLIVKEFKILSK 224 Query: 4629 LKDKIVA-EGQAIEFSCKIVGKPLPTVQ-W---YKG--DKLIKPSKYFQMSRTADEYTLR 4681 +D ++A G +++ +C I P TV W Y G +L+ + T ++ L+ Sbjct: 225 SQDYLMAIVGDSLKVNC-ITSDPNATVSLWVKKYDGVPTRLVPDDDKLILKGT--KFVLQ 281 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVT--VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739 + DEG Y C N G+V + +Q D + P I+ Sbjct: 282 --KVTLSDEGLYSCEGRNQRGKVVRKTMGQFIPSQGGYKDPKAHIYPSAKILPITNSSNF 339 Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQM---IHEG---NNAVLLIGNTYEEDTGTFTC 4793 + I T WL+ G +P + +H+G N A+L+I + ++D G +TC Sbjct: 340 SCVALGDMI--TFSWLKNGTAVPANHVMILSPRVHQGHILNEALLMIRDARKDDAGIYTC 397 Query: 4794 RATTA---AGQVETSAKLVVK 4811 R T+ +AKLV++ Sbjct: 398 RVTSGLQPGYSHSANAKLVIE 418 Score = 38.7 bits (86), Expect = 0.11 Identities = 21/63 (33%), Positives = 31/63 (49%) Query: 790 FEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVN 849 F A +PT +V+W K+ T ++ + S G+ L LR +D G+Y AVN Sbjct: 1142 FYADCFATGNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVN 1201 Query: 850 KLG 852 LG Sbjct: 1202 SLG 1204 Score = 38.3 bits (85), Expect = 0.15 Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%) Query: 2386 DNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDED 2445 D I+ G+ + DC G+PT KV+W + + ++ + + G+ + + +R++D Sbjct: 1134 DPIKFGEVFYADC--FATGNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDD 1191 Query: 2446 EGVYMCRASNLLG 2458 G Y C A N LG Sbjct: 1192 LGNYECVAVNSLG 1204 Score = 37.9 bits (84), Expect = 0.20 Identities = 35/139 (25%), Positives = 55/139 (39%), Gaps = 27/139 (19%) Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG-----------------HRYRTSNDF 1899 +E S +C + P P +R WY +G+VL H + N+ Sbjct: 1024 NETSSVALQCHVTGNPPPTVR--WYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDNEE 1081 Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959 + + Y DSG Y C+A+N+LGQ L+VQ SI+R +E ++ Sbjct: 1082 SYTLVVCKASYN-DSGSYECQAVNSLGQDKDQGYLDVQVPPSILR-------IEPDNFIA 1133 Query: 1960 DDSRYKRAVQDDSFVVEKP 1978 D ++ D F P Sbjct: 1134 DPIKFGEVFYADCFATGNP 1152 Score = 37.5 bits (83), Expect = 0.26 Identities = 58/258 (22%), Positives = 98/258 (37%), Gaps = 26/258 (10%) Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166 +LE++ D+G Y+C A K + +S + ++ P T + ++ + S Sbjct: 973 ILEVVNASPNDTGHYTCAAKKKNNRDIVSTSI-FMEVVAVSAP--TVRLDDLT-TNETSS 1028 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226 +C V +P + WY +G+ + + ++ D + ++ + D+ E Sbjct: 1029 VALQCHVT--GNPPPTVRWYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDNEE----- 1081 Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286 Y +A+ Y G Y E +SL + ++ L Q PS EP FI Sbjct: 1082 --SYTLVVCKAS---YNDSGSY-ECQAVNSLGQDKDQGYLD--VQVPPSILRIEPDNFIA 1133 Query: 3287 QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILY 3346 D K E F A +P KV+W + + G L Sbjct: 1134 ---DPIKFGEV----FYADCFATGNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFAS 1186 Query: 3347 CYEENSGEYECVATNKLG 3364 E++ G YECVA N LG Sbjct: 1187 LREDDLGNYECVAVNSLG 1204 Score = 36.3 bits (80), Expect = 0.61 Identities = 21/54 (38%), Positives = 26/54 (48%) Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724 +P K++W K T A + S+ G L SLR DD G Y C A N LG Sbjct: 1151 NPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVNSLG 1204 Score = 35.5 bits (78), Expect = 1.1 Identities = 18/55 (32%), Positives = 29/55 (52%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718 G+PT K++W K ++ ++ S + G+ L SL D G Y C AV++ G Sbjct: 1150 GNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVNSLG 1204 Score = 34.3 bits (75), Expect = 2.5 Identities = 31/120 (25%), Positives = 43/120 (35%), Gaps = 4/120 (3%) Query: 3113 TKTTDSGTYSCRATNKWGQAEI-SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFEC 3171 T TD G Y CR T G+ + SV V S KPR + + +G S C Sbjct: 84 TSNTDRGYYQCRTTLPDGRGRLESVGYITVFLSNLVKPRILVTPSQL-SVVEGASVTLTC 142 Query: 3172 TVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKY 3230 T V + WY + + + T D L + + G Y CR N + Sbjct: 143 T-VQASSQVGAVTWYKDATQLADGVQDYTSDDSLHKNTLRLTNVGKDEGGMYECRVKNSF 201 Score = 33.9 bits (74), Expect = 3.2 Identities = 41/160 (25%), Positives = 60/160 (37%), Gaps = 28/160 (17%) Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627 T L + +D+G Y C N G A+ + +P D KP IE Sbjct: 633 TNELSLTNVTKEDAGSYMCEKKNRIGAT---AQASIYVPVL-DTTKPSVN--------IE 680 Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK----------PSKY---FQMSRT 4674 + E + C + G P P + WY+G I PS++ ++ S Sbjct: 681 K-NNYSAEENEVSRIRCVVSGSPWPKISWYRGGIPIVTCEGGQFPECPSRFSNGYRASVV 739 Query: 4675 ADEYT-LRISEA-FPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 Y+ L I + +P D + CVA N AG A L V Sbjct: 740 KYSYSELEIKNSLYPRDNAMFACVATNVAGSTRDTAALNV 779 Score = 33.5 bits (73), Expect = 4.3 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Query: 1364 EFDYVALDLL-SVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404 ++ Y L++ S+YP D+ ++ C ATN G + AL V+A Sbjct: 740 KYSYSELEIKNSLYPRDNAMFACVATNVAGSTRDTAALNVLA 781 Score = 33.1 bits (72), Expect = 5.7 Identities = 41/192 (21%), Positives = 72/192 (37%), Gaps = 15/192 (7%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 P+ + V EG C V VTW+ + Q+ D + + L Sbjct: 121 PRILVTPSQLSVVEGASVTLTCTVQASSQVGAVTWYKDATQLADGVQDYTSDDSLHKNTL 180 Query: 451 MITNVTLSDSGVVTCVARNK-SGETAFQCR-LNVIEKEQVVAPKFVERFSTLNVREGEPV 508 +TNV + G+ C +N S ++ +I KE + K + + G+ + Sbjct: 181 RLTNVGKDEGGMYECRVKNSFSYVNSYNAEPTRLIVKEFKILSKSQDYLMAI---VGDSL 237 Query: 509 VLNARAVGTPTPRIT-WQK--DGVP--IIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563 +N P ++ W K DGVP ++P+ + ++ G L + SD Y C Sbjct: 238 KVNC-ITSDPNATVSLWVKKYDGVPTRLVPDDD-KLILKGTKFVLQ--KVTLSDEGLYSC 293 Query: 564 TAQNVAGSTATR 575 +N G + Sbjct: 294 EGRNQRGKVVRK 305 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/78 (29%), Positives = 31/78 (39%) Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536 KV+W K + T G+ L L +D G Y C AVN +GT + RL Sbjct: 1155 KVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVNSLGTKKKIYRLMS 1214 Query: 1537 RSTTDIVRSTQNEAGLEQ 1554 T S N G+ + Sbjct: 1215 PPTAGKQLSRDNNVGISK 1232 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 16/79 (20%) Query: 1461 HVHFECKLEPVTDSN----------LKVEWFKNGQPVTIGH------RFRPIHDFGYVAL 1504 H++ K+ P+T+S+ + W KNG V H R H L Sbjct: 323 HIYPSAKILPITNSSNFSCVALGDMITFSWLKNGTAVPANHVMILSPRVHQGHILNEALL 382 Query: 1505 DIIDLIAEDSGIYTCRAVN 1523 I D +D+GIYTCR + Sbjct: 383 MIRDARKDDAGIYTCRVTS 401 >SB_14313| Best HMM Match : I-set (HMM E-Value=1.8e-21) Length = 221 Score = 67.7 bits (158), Expect = 2e-10 Identities = 55/187 (29%), Positives = 78/187 (41%), Gaps = 23/187 (12%) Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449 AP F + + + RDV E K C +GRP P VTW +N + + + +GN Sbjct: 35 APAFNQPLDRSRDVAEDKDFSITCSASGRPAPNVTW-VNKT------SGSPVAHGTGNAT 87 Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L + + +GV C A N G A + + V P + VR GE + Sbjct: 88 LSLLKIQRHQAGVYQCQAINNVGRGAITQDITI----NVQYPPEITPIQNTTVRAGETIT 143 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN-V 568 L G PTP ++W K G H+ GG + A +D Y CTA N V Sbjct: 144 LTCAVAGNPTPSVSWSKAGSG---------HSTGG-NVFTRAGATKADTGQYVCTAVNTV 193 Query: 569 AGSTATR 575 G+T T+ Sbjct: 194 TGNTQTK 200 Score = 54.4 bits (125), Expect = 2e-06 Identities = 49/215 (22%), Positives = 84/215 (39%), Gaps = 25/215 (11%) Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPL-KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662 S P + +P+T P +PL + + VAE + +C G+P P V W Sbjct: 17 SEPFPEKFDEPKTAKNTKAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPNVTW------ 70 Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722 + + ++ TL + + G Y+C A N+ GR + + + P Sbjct: 71 VNKTSGSPVAHGTGNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITI----NVQYPP 126 Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782 +TP+++ V G+ + P++ W + G+ G N G Sbjct: 127 EITPIQNTTVRAGETITLTCAVAGNPTPSVSWSKAGS---------GHSTGGNVFTRAGA 177 Query: 4783 TYEEDTGTFTCRA-TTAAGQVET---SAKLVVKSK 4813 T + DTG + C A T G +T S ++VK K Sbjct: 178 T-KADTGQYVCTAVNTVTGNTQTKTASTYVMVKCK 211 Score = 39.1 bits (87), Expect = 0.086 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 13/114 (11%) Query: 2349 GLEKI-RELESAEPFKRPEIPEPVTRQR---PVFTQPLQNIDNIQEGQTAHFDCRLIPVG 2404 G E I R S+EPF + EP T + P F QPL ++ E + C G Sbjct: 6 GYELITRTTASSEPFPE-KFDEPKTAKNTKAPAFNQPLDRSRDVAEDKDFSITCSAS--G 62 Query: 2405 DPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 P V W + +S H G ++++ ++ GVY C+A N +G Sbjct: 63 RPAPNVTW------VNKTSGSPVAHGTGNATLSLLKIQRHQAGVYQCQAINNVG 110 Score = 38.3 bits (85), Expect = 0.15 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 11/110 (10%) Query: 1831 QRREDVEVAVN-QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889 ++ ++ + A N +AP F L+ ++E + C P PN V W K S Sbjct: 22 EKFDEPKTAKNTKAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPN--VTWV--NKTSGS 77 Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQ 1937 + T N A L +L + +G Y C+AINN+G+ I +NVQ Sbjct: 78 PVAHGTGN----ATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITINVQ 123 Score = 36.3 bits (80), Expect = 0.61 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 17/139 (12%) Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 G L +L + +G Y C+A N G+ I+ + Q P T IQN ++ Sbjct: 84 GNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITI----NVQYPPEITPIQNTT-VRA 138 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G++ C V +P + W G HST G V A D+G+YV Sbjct: 139 GETITLTCAV--AGNPTPSVSWSKAGS--GHST--------GGNVFTRAGATKADTGQYV 186 Query: 3224 CRAYNKYGEDFTRATINCY 3242 C A N + T + Y Sbjct: 187 CTAVNTVTGNTQTKTASTY 205 Score = 35.5 bits (78), Expect = 1.1 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 15/101 (14%) Query: 1708 TQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR--NGVPIEASNRLTTMHD 1764 T+AP F P+ R VAE++ F G P V W+ +G P+ H Sbjct: 33 TKAPAFNQPLDRSRDVAEDK--DFSITCSASGRPAPNVTWVNKTSGSPVA--------HG 82 Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQ 1803 G L++ + +G Y C+AIN +G A+T T+ VQ Sbjct: 83 TGNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITINVQ 123 Score = 34.7 bits (76), Expect = 1.9 Identities = 43/187 (22%), Positives = 67/187 (35%), Gaps = 26/187 (13%) Query: 4406 KPSKPPIFTKKMQPCR-VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464 K +K P F + + R V E + G P P + W + SP +T Sbjct: 31 KNTKAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPNVTWVNKT---SGSPVAHGTGNAT 87 Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524 S+L I++ + V+ A N G + ++ + + PP T QN Sbjct: 88 LSLLKIQR---HQAGVYQCQAINNVGRGAITQDITINVQ--------YPPEIT-PIQNTT 135 Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584 V +G+ + L V G V W K G G A D+G+Y Sbjct: 136 VRAGETITLTCAVAGNPTPSVSWSKAGSG----------HSTGGNVFTRAGATKADTGQY 185 Query: 4585 ECVAINS 4591 C A+N+ Sbjct: 186 VCTAVNT 192 Score = 34.3 bits (75), Expect = 2.5 Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 11/122 (9%) Query: 2616 WEQIQLKEAAMNKVPEMFVDTGVQQ---APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672 +E I A+ PE F + + AP F L + E + + R P Sbjct: 7 YELITRTTASSEPFPEKFDEPKTAKNTKAPAFNQPLDRSRDVAEDKDFSITCSASGRPAP 66 Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732 N + W V T+G+ + G TLS+ ++ +G+Y C+A N +G T I Sbjct: 67 N--VTW----VNKTSGSPV--AHGTGNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDI 118 Query: 2733 KI 2734 I Sbjct: 119 TI 120 Score = 34.3 bits (75), Expect = 2.5 Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 9/106 (8%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P F QPL V+E K+ + C G P V W + T GS + G Sbjct: 36 PAFNQPLDRSRDVAEDKDFSITC--SASGRPAPNVTWVNK----TSGS--PVAHGTGNAT 87 Query: 1237 LDIIHATSADTGEYTVRAVNHLG-SAHTSAIVRVIERSDIVTDTQN 1281 L ++ G Y +A+N++G A T I ++ +T QN Sbjct: 88 LSLLKIQRHQAGVYQCQAINNVGRGAITQDITINVQYPPEITPIQN 133 Score = 33.9 bits (74), Expect = 3.2 Identities = 38/134 (28%), Positives = 55/134 (41%), Gaps = 15/134 (11%) Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEAT 2000 S+++ +H++ + + Q + + R QD + V+ P PI+N V G + L T Sbjct: 89 SLLKIQRHQAGVYQCQAINNVGR-GAITQDITINVQYPPEITPIQNTTVRAGETITL--T 145 Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV-G 2059 +PT V W G GH G A DTG Y+C A N V G Sbjct: 146 CAVAGNPTPSVSWSKAG----SGH------STGGNVFTRAGATKADTGQYVCTAVNTVTG 195 Query: 2060 EAVT-TSSVKVDAK 2072 T T+S V K Sbjct: 196 NTQTKTASTYVMVK 209 Score = 32.3 bits (70), Expect = 9.9 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 12/100 (12%) Query: 904 ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLK--DGRPVEASSRITTF 961 ++T+ P F P+ + E F G V W+ G PV + Sbjct: 31 KNTKAPAFNQPLDRSRDVAED--KDFSITCSASGRPAPNVTWVNKTSGSPVAHGT----- 83 Query: 962 FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 G L++ + H AG Y C+A N +G+ + ++TI Sbjct: 84 ---GNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITI 120 >SB_30290| Best HMM Match : I-set (HMM E-Value=1.4e-21) Length = 250 Score = 66.9 bits (156), Expect = 4e-10 Identities = 54/188 (28%), Positives = 76/188 (40%), Gaps = 23/188 (12%) Query: 390 LAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448 +AP F + RDV E C +GRP P VTW +N + + + +G+ Sbjct: 74 VAPAFTSSLSSSRDVAENGDVTVTCSASGRPAPNVTW-VNKT------SGSPVAHGTGSA 126 Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508 L + + +GV C A N G A + + V P + VR GE + Sbjct: 127 TLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTI----NVQYPPEITPIQNTTVRAGETI 182 Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN- 567 L G PTP ++W K G H+ GG + A +D Y CTA N Sbjct: 183 TLTCAVAGNPTPSVSWSKTGSG---------HSTGG-NVFTKAGATKADTGQYVCTAVNT 232 Query: 568 VAGSTATR 575 V G+T TR Sbjct: 233 VTGNTQTR 240 Score = 49.2 bits (112), Expect = 8e-05 Identities = 39/172 (22%), Positives = 65/172 (37%), Gaps = 21/172 (12%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 VAE + +C G+P P V W + + ++ TL + + G Y Sbjct: 88 VAENGDVTVTCSASGRPAPNVTW------VNKTSGSPVAHGTGSATLSLLKIQRHQAGVY 141 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753 +C A N GRV + + + P +TP+++ V G+ + P++ Sbjct: 142 QCQAINDVGRVAITQDVTIN----VQYPPEITPIQNTTVRAGETITLTCAVAGNPTPSVS 197 Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA-TTAAGQVET 4804 W + G+ G N G T + DTG + C A T G +T Sbjct: 198 WSKTGS---------GHSTGGNVFTKAGAT-KADTGQYVCTAVNTVTGNTQT 239 Score = 46.0 bits (104), Expect = 8e-04 Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 22/148 (14%) Query: 4512 VPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570 V P+FT + + + +V V + +G +V W+ N P + G+ T Sbjct: 74 VAPAFTSSLSSSRDVAENGDVTVTCSASGRPAPNVTWV-NKTSGSP-----VAHGTGSAT 127 Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 L +L+ +G Y+C AIN G + +++ PPEI P++ Sbjct: 128 LSLLKIQRHQAGVYQCQAINDVGRVAITQDVTINV--------------QYPPEIT-PIQ 172 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 + V G+ I +C + G P P+V W K Sbjct: 173 NTTVRAGETITLTCAVAGNPTPSVSWSK 200 Score = 41.1 bits (92), Expect = 0.021 Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 8/116 (6%) Query: 2619 IQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEW 2678 ++++ ++ P + ++ AP FT+ L S + E V + R PN + W Sbjct: 53 VKIRTSSSPLSPSASWELNIKVAPAFTSSLSSSRDVAENGDVTVTCSASGRPAPN--VTW 110 Query: 2679 FKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 V T+G+ + G TLS+ ++ +G+Y C+A N +G T + I Sbjct: 111 ----VNKTSGSPV--AHGTGSATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTI 160 Score = 38.7 bits (86), Expect = 0.11 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%) Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896 E+ + AP F + L+ ++E C P PN V W K S + T Sbjct: 69 ELNIKVAPAFTSSLSSSRDVAENGDVTVTCSASGRPAPN--VTWV--NKTSGSPVAHGT- 123 Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQ 1937 G A L +L + +G Y C+AIN++G+ + +NVQ Sbjct: 124 ---GSATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTINVQ 163 Score = 37.9 bits (84), Expect = 0.20 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 12/98 (12%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRPFATGSRVHTLNDFGF 3752 P FT + + DV E G V C G P + W + +G P A G+ G Sbjct: 76 PAFTSSLSSSRDVAENGDVTVTCSAS--GRPAPNVTWVNKTSGSPVAHGT--------GS 125 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 L + I AG Y C+A N G T +T + + Sbjct: 126 ATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTINVQ 163 Score = 37.1 bits (82), Expect = 0.35 Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 15/134 (11%) Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEAT 2000 S+++ +H++ + + Q + D R QD + V+ P PI+N V G + L T Sbjct: 129 SLLKIQRHQAGVYQCQAINDVGRVA-ITQDVTINVQYPPEITPIQNTTVRAGETITL--T 185 Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV-G 2059 +PT V W G GH G A DTG Y+C A N V G Sbjct: 186 CAVAGNPTPSVSWSKTG----SGH------STGGNVFTKAGATKADTGQYVCTAVNTVTG 235 Query: 2060 EAVT-TSSVKVDAK 2072 T T+S V K Sbjct: 236 NTQTRTASTYVIVK 249 Score = 36.7 bits (81), Expect = 0.46 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 17/139 (12%) Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 G L +L + +G Y C+A N G+ I+ + Q P T IQN ++ Sbjct: 124 GSATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTI----NVQYPPEITPIQNTT-VRA 178 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G++ C V +P + W G HST G V A D+G+YV Sbjct: 179 GETITLTCAV--AGNPTPSVSWSKTGS--GHST--------GGNVFTKAGATKADTGQYV 226 Query: 3224 CRAYNKYGEDFTRATINCY 3242 C A N + T + Y Sbjct: 227 CTAVNTVTGNTQTRTASTY 245 Score = 34.3 bits (75), Expect = 2.5 Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 14/119 (11%) Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866 SL +H++ + + Q + D R +DV + V Q P IT + T + G++ C Sbjct: 129 SLLKIQRHQAGVYQCQAINDVGRVAITQDVTINV-QYPPEITPIQN-TTVRAGETITLTC 186 Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925 + P P+ V W G SGH N F A D+G+Y C A+N + Sbjct: 187 AVAGNPTPS--VSWSKTG----SGHS-TGGNVFTKAG-----ATKADTGQYVCTAVNTV 233 Score = 33.9 bits (74), Expect = 3.2 Identities = 42/182 (23%), Positives = 64/182 (35%), Gaps = 26/182 (14%) Query: 4411 PIFTKKMQPCR-VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 P FT + R V E+ G P P + W + SP +T S+L Sbjct: 76 PAFTSSLSSSRDVAENGDVTVTCSASGRPAPNVTWVNKT---SGSPVAHGTGSATLSLLK 132 Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529 I++ + V+ A N G + ++ + + PP T QN V +G+ Sbjct: 133 IQR---HQAGVYQCQAINDVGRVAITQDVTINVQ--------YPPEIT-PIQNTTVRAGE 180 Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589 + L V G V W K G G A D+G+Y C A+ Sbjct: 181 TITLTCAVAGNPTPSVSWSKTGSG----------HSTGGNVFTKAGATKADTGQYVCTAV 230 Query: 4590 NS 4591 N+ Sbjct: 231 NT 232 Score = 33.5 bits (73), Expect = 4.3 Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 21/122 (17%) Query: 1304 DITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGDQTMRVEWF--CNGKPIKTGHRFR 1360 ++ + AP F+ +L + V E +V + C G V W +G P+ Sbjct: 69 ELNIKVAPAFTSSLSSSRDVAENGDVTVTCSAS--GRPAPNVTWVNKTSGSPV------- 119 Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK 1420 A+ L LL + +GVY CQA N +G RV +D+ + Q+P + Sbjct: 120 -AHGTGSATLSLLKIQRHQAGVYQCQAINDVG--------RVAITQDVTINVQYPPEITP 170 Query: 1421 IQ 1422 IQ Sbjct: 171 IQ 172 Score = 32.7 bits (71), Expect = 7.5 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 15/102 (14%) Query: 1707 ITQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR--NGVPIEASNRLTTMH 1763 I AP FT + R VAEN G P V W+ +G P+ H Sbjct: 72 IKVAPAFTSSLSSSRDVAEN--GDVTVTCSASGRPAPNVTWVNKTSGSPVA--------H 121 Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQ 1803 G L++ + +G Y C+AIN++G A+T T+ VQ Sbjct: 122 GTGSATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTINVQ 163 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/85 (31%), Positives = 35/85 (41%), Gaps = 13/85 (15%) Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231 I+ P + P+ N V G+ I L C + G+PT V W G + G T Sbjct: 160 INVQYPPEITPIQNTT-VRAGETITLTCAVA--GNPTPSVSWSKTGSGHSTGGNVFTKAG 216 Query: 1232 FGFVALDIIHATSADTGEYTVRAVN 1256 AT ADTG+Y AVN Sbjct: 217 ----------ATKADTGQYVCTAVN 231 >SB_24384| Best HMM Match : I-set (HMM E-Value=4.3e-31) Length = 1399 Score = 66.5 bits (155), Expect = 5e-10 Identities = 64/217 (29%), Positives = 86/217 (39%), Gaps = 28/217 (12%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKN--GKKVQPDIRN---KILEED 4566 PP FT+T +N N T + +L V V W G V + K Sbjct: 537 PPQFTMTPRNSNATLNRTTQLHCAVASANLRTVITWHMRPVGSSVLTPVDTLDPKRFLVL 596 Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626 TL+I D Y C A N G +A + +P + D + Sbjct: 597 ANMTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIFVPPSFD---------------V 641 Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKYFQMSRTADEYTLRISEA 4685 P KD V +G + CK VG P PT+ WY KG K K+F++ + Y I E Sbjct: 642 LP-KDLEVPQGGSPTLQCKGVGDPRPTITWYRKGSKTFP--KHFKVRPSGSLY---IREI 695 Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722 ED+G Y C A NS G T +KV + DN+P Sbjct: 696 TKEDQGTYVCQADNSVGTATAQVIIKVFTACRIDNIP 732 Score = 57.2 bits (132), Expect = 3e-07 Identities = 71/288 (24%), Positives = 111/288 (38%), Gaps = 37/288 (12%) Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYPQDSGKYECVAIN 4590 +D KV V+W K+ + LE E +L + A +G+Y C A N Sbjct: 462 IDCKVIADPRAKVFWTKSRPWPNEQGQLSRLEFLEFSNGSLYVRRARMSYTGQYYCTAAN 521 Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650 SA E V APP+ ++ + + C + Sbjct: 522 SAAFDIGSFEIKVG----------------APPQFTMTPRNSNATLNRTTQLHCAVASAN 565 Query: 4651 LPTV-QWYK---GDKLIKPSKYFQMSR--TADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 L TV W+ G ++ P R TL I DE Y C A N G Sbjct: 566 LRTVITWHMRPVGSSVLTPVDTLDPKRFLVLANMTLMIKNLKKSDEAAYVCTANNPVGTK 625 Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPE 4763 + A LK+ P D LP +D+ V +G + + +PTI W R+G+ P+ Sbjct: 626 SSEAFLKIFVPPSFDVLP-----KDLEVPQGGSPTLQCKGVGDPRPTITWYRKGSKTFPK 680 Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 F++ G+ L I +ED GT+ C+A + G +A++++K Sbjct: 681 --HFKVRPSGS---LYIREITKEDQGTYVCQADNSVG--TATAQVIIK 721 Score = 53.6 bits (123), Expect = 4e-06 Identities = 52/189 (27%), Positives = 70/189 (37%), Gaps = 17/189 (8%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEV-TWFINDRQIR-----DDYNHKILVNES 445 PQF ++ + T + T+ C V V TW + D + K + Sbjct: 538 PQFTMTPRNSNATLNRTTQLHCAVASANLRTVITWHMRPVGSSVLTPVDTLDPKRFL-VL 596 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505 N LMI N+ SD C A N G + + L + V P F L V +G Sbjct: 597 ANMTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIF-----VPPSFDVLPKDLEVPQG 651 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 L + VG P P ITW + G P ++ G +L I D Y C A Sbjct: 652 GSPTLQCKGVGDPRPTITWYRKGSKTFPK-HFKVRPSG---SLYIREITKEDQGTYVCQA 707 Query: 566 QNVAGSTAT 574 N G TAT Sbjct: 708 DNSVG-TAT 715 Score = 49.2 bits (112), Expect = 8e-05 Identities = 54/253 (21%), Positives = 95/253 (37%), Gaps = 6/253 (2%) Query: 94 KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 K+ +P V WT+ + E + S + + SL +++ G+Y CTA N Sbjct: 465 KVIADPRAKVFWTKSRPWPNEQGQLSRLEFLEFSNGSLYVRRARMSYTGQYYCTAANSAA 524 Query: 154 EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213 I S I+ G T H A + T + + V + T Sbjct: 525 FDIGSFEIKV-GAPPQFTMTPRNSNATLNRTTQLHCAVASANLRTVITWHMRPVGSSVLT 583 Query: 214 DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVS-PPKIAQKP 272 + D + L + ++S YV ++ + T+ + + PP P Sbjct: 584 PVDTLDPKRFLVLANMTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIFVPPSFDVLP 643 Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332 ++ ++ +G Q + G+PRP +TW++ G + KH +L +R K D Sbjct: 644 KDLEVPQGGSPTLQCKGVGDPRPTITWYRKGSKTF--PKH--FKVRPSGSLYIREITKED 699 Query: 333 SGHYTLLAENPNG 345 G Y A+N G Sbjct: 700 QGTYVCQADNSVG 712 Score = 48.8 bits (111), Expect = 1e-04 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP F+ + K+ QGG+ + K G+P P ++W RK +K ++ + S Sbjct: 636 PPSFDVLPKDLEVPQGGSPTLQCKGVGDPRPTITWYRKG------SKTFPKHFKVRPSGS 689 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162 L I++I D+G Y C A N G A V I+ Sbjct: 690 LYIREITKEDQGTYVCQADNSVGTATAQVIIK 721 Score = 46.0 bits (104), Expect = 8e-04 Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753 PP F V KD ++VP+GG C+ VGDP I W+ G T + + G Sbjct: 636 PPSFDVLPKD-LEVPQGGSPTLQCK--GVGDPRPTITWYRKGSK--TFPKHFKVRPSG-- 688 Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSAT 3780 +L I I D G Y C+A N G+AT Sbjct: 689 SLYIREITKEDQGTYVCQADNSVGTAT 715 Score = 45.6 bits (103), Expect = 0.001 Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 14/128 (10%) Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 L+I+ + D A + A N GT A L + VPPSF + +++ V Sbjct: 601 LMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKI----------FVPPSFDVLPKDLEVPQ 650 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 G L K G + W + G K P K + + +L I E +D G Y C Sbjct: 651 GGSPTLQCKGVGDPRPTITWYRKGSKTFP----KHFKVRPSGSLYIREITKEDQGTYVCQ 706 Query: 4588 AINSAGEA 4595 A NS G A Sbjct: 707 ADNSVGTA 714 Score = 43.2 bits (97), Expect = 0.005 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357 TK + + P F ++E +G + L+C+ VGD + W+ G H Sbjct: 624 TKSSEAFLKIFVPPSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKH 681 Query: 1358 -RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 + RP+ +L + + ED G Y CQA N +G A ++V Sbjct: 682 FKVRPSG-----SLYIREITKEDQGTYVCQADNSVGTATAQVIIKV 722 Score = 42.3 bits (95), Expect = 0.009 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 10/120 (8%) Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691 +++ PP F V K + +GG + + VGDP I W + G S F F+ Sbjct: 632 KIFVPPSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKG-----SKTFPKHFKV 684 Query: 692 GYI-SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERT--SQHPETLQYIQ 748 SL + + +D G Y C+A ++ G A + ++ V I+ H LQ+ + Sbjct: 685 RPSGSLYIREITKEDQGTYVCQADNSVGTATAQVIIKVFTACRIDNIPFGSHEPKLQFFR 744 Score = 41.1 bits (92), Expect = 0.021 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 5/91 (5%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P F + +D +V +G C+ G P P +TW+ R+ + V SG+ L Sbjct: 637 PSFDVLPKDLEVPQGGSPTLQCKGVGDPRPTITWY---RKGSKTFPKHFKVRPSGS--LY 691 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 I +T D G C A N G Q + V Sbjct: 692 IREITKEDQGTYVCQADNSVGTATAQVIIKV 722 Score = 40.3 bits (90), Expect = 0.037 Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 6/92 (6%) Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037 P F K+ EV +G L+ V DP + WY G H FK Sbjct: 637 PSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKH-FKVRPSGSLYIR 693 Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 +I ED GTY+C+A N+VG A +KV Sbjct: 694 EIT---KEDQGTYVCQADNSVGTATAQVIIKV 722 Score = 39.1 bits (87), Expect = 0.086 Identities = 39/152 (25%), Positives = 66/152 (43%), Gaps = 11/152 (7%) Query: 3502 GEAVTTASMKVQGKRNIILESQ--LPKGMEGTIDKIAALEGYSGTVDTLTPEA--ESGNP 3557 G +V T + KR ++L + + K ++ + D+ A + + V T + EA + P Sbjct: 578 GSSVLTPVDTLDPKRFLVLANMTLMIKNLKKS-DEAAYVCTANNPVGTKSSEAFLKIFVP 636 Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P F P DL + + S +C+ V D + W+ G T + + G L Sbjct: 637 PSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGSK--TFPKHFKVRPSGS--L 690 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 I + + D G Y C+A N G AT ++V Sbjct: 691 YIREITKEDQGTYVCQADNSVGTATAQVIIKV 722 Score = 38.7 bits (86), Expect = 0.11 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 7/88 (7%) Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499 + + P F PK +E V +G +CK V D + W++ G T F+ + Sbjct: 633 IFVPPSFDVLPKDLE-VPQGGSPTLQCK--GVGDPRPTITWYRKGSK-TFPKHFK-VRPS 687 Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGT 1527 G +L I ++ ED G Y C+A N VGT Sbjct: 688 G--SLYIREITKEDQGTYVCQADNSVGT 713 Score = 38.3 bits (85), Expect = 0.15 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 6/79 (7%) Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182 +G +C+ + DP TI W+ G K H ++ +I ED GTY Sbjct: 650 QGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKH-FKVRPSGSLYIREIT---KEDQGTY 703 Query: 2183 MCKATNKLGEAVNTCTLKV 2201 +C+A N +G A +KV Sbjct: 704 VCQADNSVGTATAQVIIKV 722 Score = 37.9 bits (84), Expect = 0.20 Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 9/126 (7%) Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG-KTIEASHRIRTVYAFGM 3105 PP F + KD+ ++ +G + + GD I W+ G KT ++R + + Sbjct: 636 PPSFDVLPKDL-EVPQGGSPTLQCKGV--GDPRPTITWYRKGSKTFPKHFKVRP--SGSL 690 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165 + EI TK D GTY C+A N G A V ++ + F +H ++ + G Sbjct: 691 YIREI--TKE-DQGTYVCQADNSVGTATAQVIIKVFTACRIDNIPFGSHEPKLQFFRVGS 747 Query: 3166 SAHFEC 3171 +C Sbjct: 748 VVQVQC 753 Score = 37.9 bits (84), Expect = 0.20 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P F + KD+ V + + + + VGDP+ + W R G + + + G +L Sbjct: 637 PSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGS--KTFPKHFKVRPSG--SL 690 Query: 1771 NMKYVNPEDSGTYTCRAINELGEA 1794 ++ + ED GTY C+A N +G A Sbjct: 691 YIREITKEDQGTYVCQADNSVGTA 714 Score = 37.5 bits (83), Expect = 0.26 Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 8/87 (9%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG-KLLPSGHRYRTVYDM 3884 + PP F K V + +C+ DP+ I WYR G K P + R Sbjct: 633 IFVPPSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKHFKVRP---S 687 Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911 G SL I + ED G Y+C+A N G Sbjct: 688 G--SLYIREITKEDQGTYVCQADNSVG 712 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 8/102 (7%) Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKN--GQRLINS----NKHEIIT 316 +PP+ PRNS Q + S N R +TW G ++ + + Sbjct: 536 APPQFTMTPRNSNATLNRTTQLHCAVASANLRTVITWHMRPVGSSVLTPVDTLDPKRFLV 595 Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 N TL ++N +KSD Y A NP G + +L + P Sbjct: 596 LAN-MTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIFVP 636 Score = 35.9 bits (79), Expect = 0.80 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 10/96 (10%) Query: 1178 VFVQPLSNPPP----VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233 +FV P + P V +G + L+C+ +GDP + W+ G S T FK Sbjct: 633 IFVPPSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKG-SKTFPKHFKVRPSGS 689 Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269 +I T D G Y +A N +G+A I++V Sbjct: 690 LYIREI---TKEDQGTYVCQADNSVGTATAQVIIKV 722 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 6/84 (7%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-TFSTKSIL 4468 PP F + V + + + G+P P I WYR K S F H L Sbjct: 636 PPSFDVLPKDLEVPQGGSPTLQCKGVGDPRPTITWYR-----KGSKTFPKHFKVRPSGSL 690 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTA 4492 IR++ ED + A+N GTA Sbjct: 691 YIREITKEDQGTYVCQADNSVGTA 714 Score = 34.7 bits (76), Expect = 1.9 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 6/71 (8%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 + +G + C+ VGDP + W+R K + + K G S+ I + ED+G Sbjct: 648 VPQGGSPTLQCK--GVGDPRPTITWYR--KGSKTFPKHFKVRPSG--SLYIREITKEDQG 701 Query: 2448 VYMCRASNLLG 2458 Y+C+A N +G Sbjct: 702 TYVCQADNSVG 712 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 9/96 (9%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV- 967 P F KD + + +GG + + +GD + W + G S F Sbjct: 637 PSFDVLPKD-LEVPQGGSPTLQCK--GVGDPRPTITWYRKG-----SKTFPKHFKVRPSG 688 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003 +L I+ +T D G Y C+A N++G AT + + T Sbjct: 689 SLYIREITKEDQGTYVCQADNSVGTATAQVIIKVFT 724 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYRTSNDFGFAALDILTVYGED 1913 ++ +G S +C+ DP + WY G K + R S +L I + ED Sbjct: 647 EVPQGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKHFKVRPSG-----SLYIREITKED 699 Query: 1914 SGEYTCKAINNLGQAVSSIRLNV 1936 G Y C+A N++G A + + + V Sbjct: 700 QGTYVCQADNSVGTATAQVIIKV 722 Score = 34.3 bits (75), Expect = 2.5 Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 19/155 (12%) Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508 DP + WY G S F+ I EI+ ED G Y+C+A N+ G A Sbjct: 663 DPRPTITWYRKG-SKTFPKHFKVRPSGSLYIREITK---EDQGTYVCQADNSVGTATAQV 718 Query: 3509 SMKVQGK---RNIILESQLPK---GMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFT- 3561 +KV NI S PK G++ ++ GYS T + T G+ EF Sbjct: 719 IIKVFTACRIDNIPFGSHEPKLQFFRVGSVVQVQCYPGYS-TSEGPTTNLTCGDDGEFNE 777 Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596 + P L ECR+ P + + V+ +H+ Sbjct: 778 SMPKCKDLD-------ECRVSPSSVNDHDVKTYHD 805 Score = 33.5 bits (73), Expect = 4.3 Identities = 34/137 (24%), Positives = 47/137 (34%), Gaps = 12/137 (8%) Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165 + L I K +D Y C A N G L+ P F +++E + G Sbjct: 599 MTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIF-----VPPSFDVLPKDLE-VPQGG 652 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 S +C V DP I WY G K + +I D G YVC+ Sbjct: 653 SPTLQCK--GVGDPRPTITWYRKGSKT-FPKHFKVRPSGSLYIREIT---KEDQGTYVCQ 706 Query: 3226 AYNKYGEDFTRATINCY 3242 A N G + I + Sbjct: 707 ADNSVGTATAQVIIKVF 723 Score = 33.1 bits (72), Expect = 5.7 Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 10/115 (8%) Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN--GKP 3599 S D + E + G PP+FT TP + + N + C + N ++ + W G Sbjct: 522 SAAFDIGSFEIKVGAPPQFTMTPRNSNATLNRTTQLHCAVASANLRTV-ITWHMRPVGSS 580 Query: 3600 LLTGSRVKTINDFGFVILE-----IGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 +LT V T++ F++L I + + D Y C A N G + L++ Sbjct: 581 VLT--PVDTLDPKRFLVLANMTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKI 633 >SB_14894| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1052 Score = 65.7 bits (153), Expect = 9e-10 Identities = 82/323 (25%), Positives = 119/323 (36%), Gaps = 35/323 (10%) Query: 4508 RGGIVPPSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566 R + P FT ++ V G+ RL + +G P YWLKNG V P R +I++ Sbjct: 243 RPSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRIVKN- 301 Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626 Y L I D+G+Y CV N+ GE V P +A A P Sbjct: 302 -RY-LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMKRAFIAWPA-- 357 Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686 ++ C+ G P W K K IK + T + R+ + Sbjct: 358 ----------SHSMRLRCQATGTPPLRYHWLKDGKEIKGRRLDPYMNTT-LWFFRLKDLV 406 Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKV-----TQPDQADNLPALTPLR--------DIVVY 4733 P D G Y C+ N+ G + L+V ++P NLP T + IVV Sbjct: 407 PTDTGKYTCIVSNAYGSINHTYTLRVIAKPRSRPILQRNLPRNTSIELGGNATLDCIVVV 466 Query: 4734 EGQPAQFKTQITSKIKPTIQWL--REGALIPETPDFQMIHEGNNAV---LLIGNTYEEDT 4788 G F+ K+ T L G+ P + E L + N ++D Sbjct: 467 SGTLPDFRWLKWDKVPSTYPELDLNNGSYTLIDPVYYRTIEAGETYGVQLTVVNVTKKDL 526 Query: 4789 GTFTCRATTAAGQVETSAKLVVK 4811 G +TC + G+ SA L K Sbjct: 527 GLYTCYVSNHIGKDYVSAFLSEK 549 Score = 64.5 bits (150), Expect = 2e-09 Identities = 68/278 (24%), Positives = 112/278 (40%), Gaps = 24/278 (8%) Query: 4405 VKPS-KPPIFTKKMQPC-RVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462 ++PS P FTK ++ +V E AR + G P P W + P+ P +I Sbjct: 242 LRPSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVV--PSHRIRIV 299 Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522 + L I+ + D+ + V N G S +L V+E R + +F Sbjct: 300 KNR-YLKIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMKRAF------ 352 Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 + + +RL + TGT P+ +WLK+GK+++ + + + + + P D+G Sbjct: 353 IAWPASHSMRLRCQATGTPPLRYHWLKDGKEIKGRRLDPYMNTT-LWFFRLKDLVPTDTG 411 Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642 KY C+ N+ G V + + +P Q P I G A Sbjct: 412 KYTCIVSNAYGSINHTYTLRV-IAKPRSRPILQRNL---------PRNTSIELGGNATLD 461 Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680 +V LP +W K DK+ PS Y ++ YTL Sbjct: 462 CIVVVSGTLPDFRWLKWDKV--PSTYPELDLNNGSYTL 497 Score = 52.8 bits (121), Expect = 7e-06 Identities = 48/181 (26%), Positives = 72/181 (39%), Gaps = 7/181 (3%) Query: 392 PQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 P+F K + V G+ R CR +G P P W N + +H+I + + N L Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVP--SHRIRIVK--NRYL 304 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 I + L D+G CV N GE L+V E + + ++R + + + L Sbjct: 305 KIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMKR-AFIAWPASHSMRL 363 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 +A GTP R W KDG I L + + + +D Y C N G Sbjct: 364 RCQATGTPPLRYHWLKDGKE-IKGRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422 Query: 571 S 571 S Sbjct: 423 S 423 Score = 46.4 bits (105), Expect = 6e-04 Identities = 28/97 (28%), Positives = 52/97 (53%), Gaps = 4/97 (4%) Query: 263 VSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321 +S PK + ++S +++ G A+ + + SG P P W KNG ++ S++ I+ + Sbjct: 246 LSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRIV---KNR 302 Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 L++++T D+G Y + N G I S +L V+ P Sbjct: 303 YLKIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEP 339 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%) Query: 3148 KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV 3207 +P+FT +++ +K G+SA +C V P W NG P+ S RI+ V + Sbjct: 248 QPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKNR--- 302 Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGE 3232 L I T D+GEY+C N YGE Sbjct: 303 YLKIKSTVLGDAGEYICVFNNTYGE 327 Score = 46.0 bits (104), Expect = 8e-04 Identities = 33/97 (34%), Positives = 43/97 (44%), Gaps = 5/97 (5%) Query: 905 STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964 S +P+F +K +K G A + R G WLK+G PV S RI N Sbjct: 245 SLSQPKFTKAVKSSYQVKLGESARLKCRAS--GVPPPYSYWLKNGLPVVPSHRIRIVKN- 301 Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 Y L IKS + DAG Y C N G+ S +L + Sbjct: 302 RY--LKIKSTVLGDAGEYICVFNNTYGEINASIHLDV 336 Score = 46.0 bits (104), Expect = 8e-04 Identities = 27/76 (35%), Positives = 34/76 (44%), Gaps = 1/76 (1%) Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN 1389 + R Q G +R W +GK IK G R P L + P D+G YTC +N Sbjct: 361 MRLRCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSN 419 Query: 1390 QLGEAVTSCALRVIAK 1405 G + LRVIAK Sbjct: 420 AYGSINHTYTLRVIAK 435 Score = 46.0 bits (104), Expect = 8e-04 Identities = 59/235 (25%), Positives = 94/235 (40%), Gaps = 30/235 (12%) Query: 3443 RLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYG 3502 R T P L+ W +GK +K G R + + + P D+G+Y C N YG Sbjct: 364 RCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422 Query: 3503 EAVTTASMKVQGK--RNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEF 3560 T +++V K IL+ LP+ + G + T+D + SG P+F Sbjct: 423 SINHTYTLRVIAKPRSRPILQRNLPRNTSIEL-------GGNATLDCIV--VVSGTLPDF 473 Query: 3561 TTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIG 3620 D + S + +N+ S + P+ + ++ +G V L + Sbjct: 474 RWLKWDKVPSTYPE-------LDLNNGSYTLI-----DPVYYRT-IEAGETYG-VQLTVV 519 Query: 3621 GVYQRDAGLYTCKATNRHGEATVSCKLQVK----GRQGIILEPQLPSHFKSGTES 3671 V ++D GLYTC +N G+ VS L K + +IL P S T S Sbjct: 520 NVTKKDLGLYTCYVSNHIGKDYVSAFLSEKIIPTTTRPVILVPTKKSKLNVNTSS 574 Score = 44.8 bits (101), Expect = 0.002 Identities = 45/187 (24%), Positives = 72/187 (38%), Gaps = 16/187 (8%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P+FT K + G+ A + +G W NG + SHRIR V Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRA--SGVPPPYSYWLKNGLPVVPSHRIRIVKNR---Y 303 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L+I T D+G Y C N +G+ S+ L+ + PRF + ++ Sbjct: 304 LKIKSTVLGDAGEYICVFNNTYGEINASIHLDV-----KEPPRFLDWNKMKRAFIAWPAS 358 Query: 3168 H-FECTVVPVDDPDMKIEWYHNGQPM--RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 H P ++ W +G+ + R + + F + D+ T D+G+Y C Sbjct: 359 HSMRLRCQATGTPPLRYHWLKDGKEIKGRRLDPYMNTTLWFFRLKDLVPT---DTGKYTC 415 Query: 3225 RAYNKYG 3231 N YG Sbjct: 416 IVSNAYG 422 Score = 44.4 bits (100), Expect = 0.002 Identities = 33/107 (30%), Positives = 47/107 (43%), Gaps = 6/107 (5%) Query: 3830 PKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 PKF +KS + V+ E R +CR P W +NG + HR R V + Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKNR---Y 303 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935 L I D+GEYIC N +GE + K+ P + N++ R Sbjct: 304 LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMKR 350 Score = 44.0 bits (99), Expect = 0.003 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 5/97 (5%) Query: 65 RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 RP P + + + + G +A+ + + G P P W + P+V ++ + N Sbjct: 243 RPSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRIVKNR 302 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161 L IK GD GEY C N YGE S+++ Sbjct: 303 Y-----LKIKSTVLGDAGEYICVFNNTYGEINASIHL 334 Score = 44.0 bits (99), Expect = 0.003 Identities = 42/193 (21%), Positives = 77/193 (39%), Gaps = 8/193 (4%) Query: 4623 PEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 P+ + +K V G++ C+ G P P W K + PS ++ + + Y L+ Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRIVK--NRY-LK 305 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA-QF 4740 I D G+Y CV N+ G + + L V +P + + + R + + + + Sbjct: 306 IKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMK--RAFIAWPASHSMRL 363 Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 + Q T WL++G I + + + DTG +TC + A G Sbjct: 364 RCQATGTPPLRYHWLKDGKEI-KGRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422 Query: 4801 QVETSAKLVVKSK 4813 + + L V +K Sbjct: 423 SINHTYTLRVIAK 435 Score = 44.0 bits (99), Expect = 0.003 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Query: 932 RLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991 R + G LR WLKDG+ ++ R+ + N +K + D G YTC NA G Sbjct: 364 RCQATGTPPLRYHWLKDGKEIKGR-RLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422 Query: 992 QATTSANLTIVTK 1004 + L ++ K Sbjct: 423 SINHTYTLRVIAK 435 Score = 41.5 bits (93), Expect = 0.016 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 5/94 (5%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P+F + ++ G+SA +CR P P W NG + HR R + Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN---RY 303 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 L I + D+GEY C N G+ +SI L+V+ Sbjct: 304 LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVK 337 Score = 41.5 bits (93), Expect = 0.016 Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 6/106 (5%) Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETT---KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFT 4023 +D K+PPRF+ + + + + + + CQ G P ++ W +GK + + R Sbjct: 334 LDVKEPPRFLDWNKMKRAFIAWPASHSMRLRCQAT--GTPPLRYHWLKDGKEIKGR-RLD 390 Query: 4024 PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069 P + + P D+G+Y C +N YG ++ KP Sbjct: 391 PYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYGSINHTYTLRVIAKP 436 Score = 41.1 bits (92), Expect = 0.021 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 5/85 (5%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167 +P F A+ S +K G+ A +CR + P+ W NG + HR R + Y Sbjct: 248 QPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN-RY- 303 Query: 2168 ALDILYTYAEDSGTYMCKATNKLGE 2192 L I T D+G Y+C N GE Sbjct: 304 -LKIKSTVLGDAGEYICVFNNTYGE 327 Score = 39.5 bits (88), Expect = 0.065 Identities = 48/210 (22%), Positives = 81/210 (38%), Gaps = 23/210 (10%) Query: 3718 RVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG 3777 R + G P +R W +G+ G R+ + + + D G+YTC +N +G Sbjct: 364 RCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422 Query: 3778 SA--TTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQ 3835 S T T ++ + +L+ LP+ S +E G + + T P F Sbjct: 423 SINHTYTLRVIAKPRSRPILQRNLPRNTS------IELGGNATLDCIVVVSGTLPDF-RW 475 Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895 +K V P P+L + + P +R + V L ++ V Sbjct: 476 LKWDKV-------------PSTYPELDLNNGSYTLIDPVYYRTIEAGETYGVQLTVVNVT 522 Query: 3896 AEDSGEYICRAVNDFGEDFTKATISCKKLP 3925 +D G Y C N G+D+ A +S K +P Sbjct: 523 KKDLGLYTCYVSNHIGKDYVSAFLSEKIIP 552 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 5/83 (6%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P+FT +K + V G CR V P W NG P R+ + + Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN---RY 303 Query: 3755 LDIDYIYARDAGEYTCRATNKWG 3777 L I DAGEY C N +G Sbjct: 304 LKIKSTVLGDAGEYICVFNNTYG 326 Score = 37.9 bits (84), Expect = 0.20 Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 6/94 (6%) Query: 3558 PEFT-TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616 P+FT S + SA +CR V W NG P++ R++ + + Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKNR---Y 303 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 L+I DAG Y C N +GE S L VK Sbjct: 304 LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVK 337 Score = 37.9 bits (84), Expect = 0.20 Identities = 41/184 (22%), Positives = 74/184 (40%), Gaps = 22/184 (11%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134 TG + W +GK I+ R+ + + TD+G Y+C +N +G Sbjct: 368 TGTPPLRYHWLKDGKEIKG-RRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYGSINH 426 Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD-PDMK-IEW------- 3185 + L + K + +P ++ ++ G +A +C VV PD + ++W Sbjct: 427 TYTLRVIAKPR-SRPILQRNLPRNTSIELGGNATLDCIVVVSGTLPDFRWLKWDKVPSTY 485 Query: 3186 ----YHNG-----QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236 +NG P+ + T I+ +G V L + D G Y C N G+D+ Sbjct: 486 PELDLNNGSYTLIDPVYYRT-IEAGETYG-VQLTVVNVTKKDLGLYTCYVSNHIGKDYVS 543 Query: 3237 ATIN 3240 A ++ Sbjct: 544 AFLS 547 Score = 37.5 bits (83), Expect = 0.26 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 1/89 (1%) Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVN 1776 MK +A + R G P LR WL++G I+ RL + +K + Sbjct: 348 MKRAFIAWPASHSMRLRCQATGTPPLRYHWLKDGKEIKG-RRLDPYMNTTLWFFRLKDLV 406 Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 P D+G YTC N G + TL V +K Sbjct: 407 PTDTGKYTCIVSNAYGSINHTYTLRVIAK 435 Score = 37.1 bits (82), Expect = 0.35 Identities = 50/194 (25%), Positives = 81/194 (41%), Gaps = 20/194 (10%) Query: 284 QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL---RVRNTQKSDSGHYTLLA 340 + + Q +G P R W K+G+ + K + + +TTL R+++ +D+G YT + Sbjct: 362 RLRCQATGTPPLRYHWLKDGKEI----KGRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIV 417 Query: 341 ENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQD 400 N G I + L V + S QR+ R T IE+ A V V Sbjct: 418 SNAYGSINHTYTLRVIAKPRSRPILQRNL------PRNTS--IELGGNATLDCIVVV--S 467 Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSD 459 + + + ++D +V YPE+ + D Y I E+ L + NVT D Sbjct: 468 GTLPDFRWLKWD-KVPST-YPELDLNNGSYTLIDPVYYRTIEAGETYGVQLTVVNVTKKD 525 Query: 460 SGVVTCVARNKSGE 473 G+ TC N G+ Sbjct: 526 LGLYTCYVSNHIGK 539 Score = 36.3 bits (80), Expect = 0.61 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 1/76 (1%) Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256 + R + G P +R W +G+ + G R Y + + DTG+YT N Sbjct: 361 MRLRCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSN 419 Query: 1257 HLGSAHTSAIVRVIER 1272 GS + + +RVI + Sbjct: 420 AYGSINHTYTLRVIAK 435 Score = 35.9 bits (79), Expect = 0.80 Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 5/92 (5%) Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502 +P+F KS V G+ +C+ V W KNG PV HR R + + Y Sbjct: 248 QPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN-RY- 303 Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 L I + D+G Y C N G S L Sbjct: 304 -LKIKSTVLGDAGEYICVFNNTYGEINASIHL 334 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 5/94 (5%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 P FT + + ++ GE+A + R + P W NG + R R + Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKNR---Y 303 Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 L+I T D+GEY+C N YGE + + V+ Sbjct: 304 LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVK 337 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 6/96 (6%) Query: 1308 MQAPQFSRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD 1366 + P+F++A+ + V+ G + L+CR V W NG P+ HR R + Sbjct: 246 LSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIR-IVKNR 302 Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 Y L + S D+G Y C N GE S L V Sbjct: 303 Y--LKIKSTVLGDAGEYICVFNNTYGEINASIHLDV 336 Score = 34.7 bits (76), Expect = 1.9 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 5/96 (5%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 PS PKF ++ ++ G+SA + R V P W NG + HR R + Sbjct: 244 PSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPP--YSYWLKNGLPVVPSHRIRIVKN 301 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372 + I + ++GEY CV N G + +L Sbjct: 302 RYLKIKSTVL---GDAGEYICVFNNTYGEINASIHL 334 Score = 34.7 bits (76), Expect = 1.9 Identities = 17/50 (34%), Positives = 25/50 (50%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 P ++ + V+ GE AR CR +G P P WL NG +V R ++ Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRI 298 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 1/66 (1%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 P +R W KDG+ I R+ N + L D G YT N G T + Sbjct: 371 PPLRYHWLKDGKEI-KGRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYGSINHTYT 429 Query: 860 IRVAAR 865 +RV A+ Sbjct: 430 LRVIAK 435 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296 P +S P+F ++ + V G++A +C+ V P + NG + + R I + Sbjct: 244 PSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPP--YSYWLKNGLPVVPSHRIRIVKN 301 Query: 2297 FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334 Y L I+ V DAGEY N G ++I + V Sbjct: 302 -RY--LKIKSTVLGDAGEYICVFNNTYGEINASIHLDV 336 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 6/94 (6%) Query: 1711 PVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769 P FT +K +V ++A + R V P WL+NG+P+ S+R+ + + Y Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN-RY-- 303 Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 L +K D+G Y C N GE S L V+ Sbjct: 304 LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVK 337 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 P+F ++S + E+ + +C+ + V P W NG P++ +R + + Y+ Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN-RYLK 305 Query: 4033 MNFGWVYPEDSGEYLCRATNLYG 4055 + + D+GEY+C N YG Sbjct: 306 IKSTVL--GDAGEYICVFNNTYG 326 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 2/70 (2%) Query: 2521 WEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGL 2580 W H+ R G P LR+ W +G E+K G R + + +V D G Sbjct: 355 WPASHS-MRLRCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGK 412 Query: 2581 YMCKAINRAG 2590 Y C N G Sbjct: 413 YTCIVSNAYG 422 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 1/63 (1%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P L+ W K+G + G RL + L + L D+G YTC +N G T + Sbjct: 371 PPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYGSINHTYT 429 Query: 2732 IKI 2734 +++ Sbjct: 430 LRV 432 >SB_31893| Best HMM Match : I-set (HMM E-Value=2e-22) Length = 767 Score = 65.7 bits (153), Expect = 9e-10 Identities = 50/182 (27%), Positives = 86/182 (47%), Gaps = 15/182 (8%) Query: 389 ALAPQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESG 446 A P+F++ + + T+ +C+V G P P VTW D+++ ++ HK++ Sbjct: 406 ATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEPVVTWRRTRDKKLSEE-RHKVVQG--- 461 Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVRE- 504 L + + D G+ C A + G + V E+ A KF++ +TL ++ Sbjct: 462 --VLYLNDPNKEDEGLYICRASSPMGSVIAAIDVTV---ERFSAVKFLKVAPATLKIKNV 516 Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 P++LN A GTP+P +TW KD V +P L+ D + I R ++D Y C Sbjct: 517 NTPIILNCTAKGTPSPTLTWYKDDV-ALPTKILK-DEDEFTAVYTIQRPSSADQGKYFCA 574 Query: 565 AQ 566 A+ Sbjct: 575 AK 576 Score = 58.8 bits (136), Expect = 1e-07 Identities = 69/290 (23%), Positives = 107/290 (36%), Gaps = 35/290 (12%) Query: 4510 GIVPPSFTLTAQ-NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568 G V P+ T+ + + +G K +G D YW K G + E + Sbjct: 321 GFVAPNITVKPPPKITLKAGSPFTFTAKASGFPVPDTYWTKEGSR----------EAIFS 370 Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628 TL +A P+DSG + A N+ G AR + +V ATK P+ IE Sbjct: 371 STLGFSKAQPEDSGTWVFNAKNAMGSARAATDIIV---ATK-------------PKFIEK 414 Query: 4629 LKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687 K+ A + + + CK+ G P P V W + + K + + L +++ Sbjct: 415 PPSKVTAFQSTSTKLECKVEGYPEPVVTW----RRTRDKKLSEERHKVVQGVLYLNDPNK 470 Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747 EDEG Y C A + G V A + V + A + P + P Sbjct: 471 EDEGLYICRASSPMGSVIAAIDVTV-ERFSAVKFLKVAPATLKIKNVNTPIILNCTAKGT 529 Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797 PT+ W ++ +P + AV I D G + C A T Sbjct: 530 PSPTLTWYKDDVALP--TKILKDEDEFTAVYTIQRPSSADQGKYFCAAKT 577 Score = 47.2 bits (107), Expect = 3e-04 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 31/224 (13%) Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535 EDS + A+N G+A+ + +++V K + PPS Q+ + +L+ Sbjct: 381 EDSGTWVFNAKNAMGSARAATDIIVATKPKFIE---KPPSKVTAFQSTS------TKLEC 431 Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595 KV G V W + K + R+K+++ L + + +D G Y C A + G Sbjct: 432 KVEGYPEPVVTWRRTRDKKLSEERHKVVQG----VLYLNDPNKEDEGLYICRASSPMGSV 487 Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655 + ++ T ++ AP + KI I +C G P PT+ Sbjct: 488 ------IAAIDVTVERFSAVKFLKVAPATL------KIKNVNTPIILNCTAKGTPSPTLT 535 Query: 4656 WYKGDKLIKPSKYFQMSRTADEYT--LRISEAFPEDEGDYKCVA 4697 WYK D + P+K + + DE+T I D+G Y C A Sbjct: 536 WYKDDVAL-PTK---ILKDEDEFTAVYTIQRPSSADQGKYFCAA 575 Score = 46.0 bits (104), Expect = 8e-04 Identities = 45/193 (23%), Positives = 79/193 (40%), Gaps = 22/193 (11%) Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYT 4679 AP ++P + G F+ K G P+P W K + SR A T Sbjct: 324 APNITVKPPPKITLKAGSPFTFTAKASGFPVPDTYWTK-----------EGSREAIFSST 372 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPA 4738 L S+A PED G + A N+ G A + V T+P + P+ + ++ Sbjct: 373 LGFSKAQPEDSGTWVFNAKNAMGSARAATDIIVATKPKFIEKPPS-----KVTAFQSTST 427 Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798 + + ++ +P + W R + + H+ VL + + +ED G + CRA++ Sbjct: 428 KLECKVEGYPEPVVTWRRTR----DKKLSEERHKVVQGVLYLNDPNKEDEGLYICRASSP 483 Query: 4799 AGQVETSAKLVVK 4811 G V + + V+ Sbjct: 484 MGSVIAAIDVTVE 496 Score = 41.5 bits (93), Expect = 0.016 Identities = 48/223 (21%), Positives = 84/223 (37%), Gaps = 17/223 (7%) Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453 A R + +KP K F+ + E + +G P P++ W R + Sbjct: 393 AMGSARAATDIIVATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEPVVTWRRTRDKKLS 452 Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513 ++ + +L + ED ++ A + G+ + ++ VE + P Sbjct: 453 EERHKV----VQGVLYLNDPNKEDEGLYICRASSPMGSVIAAIDVTVERFSAVKFLKVAP 508 Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 TL +NVN + L+ GT + W K+ + KIL+++ +T + Sbjct: 509 A--TLKIKNVNTP----IILNCTAKGTPSPTLTWYKD----DVALPTKILKDEDEFTAVY 558 Query: 4574 LEAYPQ--DSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614 P D GKY C A E +SL A K+ P+P Sbjct: 559 TIQRPSSADQGKYFCAAKTKFLEKPIGYFTQLSLAACKE-PEP 600 Score = 41.5 bits (93), Expect = 0.016 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 7/115 (6%) Query: 3825 IVSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883 IV+T PKFI + S T +S + EC+VE +P + W R S R++ V Sbjct: 404 IVATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEPV--VTWRRTRDKKLSEERHKVVQG 461 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938 + +++ ED G YICRA + G ++ ++ + P +K Sbjct: 462 VLYLNDP----NKEDEGLYICRASSPMGSVIAAIDVTVERFSAVKFLKVAPATLK 512 Score = 41.5 bits (93), Expect = 0.016 Identities = 21/92 (22%), Positives = 43/92 (46%), Gaps = 5/92 (5%) Query: 266 PKIAQKPRNSKLQ-EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PK +KP + + + + ++ G P P VTW + + ++ +H+++ L Sbjct: 409 PKFIEKPPSKVTAFQSTSTKLECKVEGYPEPVVTWRRTRDKKLSEERHKVV----QGVLY 464 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356 + + K D G Y A +P G ++ + + VE Sbjct: 465 LNDPNKEDEGLYICRASSPMGSVIAAIDVTVE 496 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 6/105 (5%) Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892 R ++ V P+FI + + S EC++E YP+P V W S R Sbjct: 398 RAATDIIVATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEP--VVTWRRTRDKKLSEER 455 Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 ++ L + ED G Y C+A + +G +++I + V+ Sbjct: 456 HKVVQ----GVLYLNDPNKEDEGLYICRASSPMGSVIAAIDVTVE 496 Score = 36.7 bits (81), Expect = 0.46 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 9/95 (9%) Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492 TDII V KP+F+ +P S + ECK+E + V W + R Sbjct: 401 TDII---VATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEP--VVTWRRTRDKKLSEER 455 Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527 + + Y + D ED G+Y CRA + +G+ Sbjct: 456 HKVVQGVLY----LNDPNKEDEGLYICRASSPMGS 486 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 6/80 (7%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 Q + K E K+ G P PVV+W R + K S ++ V L + DEG Y Sbjct: 423 QSTSTKLECKVEGYPEPVVTWRRTRD-----KKLSEERHKVVQGV-LYLNDPNKEDEGLY 476 Query: 145 TCTARNQYGEAICSVYIQPE 164 C A + G I ++ + E Sbjct: 477 ICRASSPMGSVIAAIDVTVE 496 Score = 32.3 bits (70), Expect = 9.9 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 6/90 (6%) Query: 3966 DVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPI 4025 D+ P+F+ + S+ + + +TK EC++ G P V W L + R + Sbjct: 402 DIIVATKPKFIEKPPSKVTAFQSTSTKLECKVE--GYPEPVVTWRRTRDKKLSEERHKVV 459 Query: 4026 YDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055 G + +N ED G Y+CRA++ G Sbjct: 460 Q--GVLYLND--PNKEDEGLYICRASSPMG 485 >SB_34975| Best HMM Match : F5_F8_type_C (HMM E-Value=0) Length = 909 Score = 65.3 bits (152), Expect = 1e-09 Identities = 50/205 (24%), Positives = 84/205 (40%), Gaps = 23/205 (11%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 P FT ++ + G V +G + WL NG P +++ +G+ + Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQL--SNGSLNVAA 641 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633 + G Y C+A + AG A+ +A +V +P P ++ + Sbjct: 642 VYNNGSYEGLYTCLASSEAGMAQSNASLIVDVP----------------PSVLSLRGNST 685 Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V Q I +C + G P P V W K ++I + + +RT R++ DEG Y Sbjct: 686 VILEQTINLTCLVRGDPTPAVYWKKDGQIITTATLSENNRTLTTQAFRVA-----DEGRY 740 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQA 4718 C A N AG + + + VT+ QA Sbjct: 741 ACFATNRAGNDSKSILITVTECQQA 765 Score = 64.9 bits (151), Expect = 2e-09 Identities = 50/180 (27%), Positives = 78/180 (43%), Gaps = 13/180 (7%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P+F + + + + +G F C +GRP P +TW N +H+ L N S N A + Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQ-LSNGSLNVAAV 642 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511 N S G+ TC+A +++G L +++ V P + V + + L Sbjct: 643 YNNG--SYEGLYTCLASSEAGMAQSNASL-IVD----VPPSVLSLRGNSTVILEQTINLT 695 Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 G PTP + W+KDG II L + TL + +D Y C A N AG+ Sbjct: 696 CLVRGDPTPAVYWKKDG-QIITTATLSENN----RTLTTQAFRVADEGRYACFATNRAGN 750 Score = 49.6 bits (113), Expect = 6e-05 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+ + PR+ +++G F SG P+PR+TW NG + H++ ++ + Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQL--SNGSLNVAA 641 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 S G YT LA + G ++ L V+ P Sbjct: 642 VYNNGSYEGLYTCLASSEAGMAQSNASLIVDVP 674 Score = 48.8 bits (111), Expect = 1e-04 Identities = 48/192 (25%), Positives = 74/192 (38%), Gaps = 20/192 (10%) Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLR 4681 PE + + + +G + F C G+P P + W Y G + P Q+S +L Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDAL-PQGSHQLSNG----SLN 638 Query: 4682 ISEAFPED--EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR-DIVVYEGQPA 4738 ++ + EG Y C+A + AG A L V P P++ LR + V Q Sbjct: 639 VAAVYNNGSYEGLYTCLASSEAGMAQSNASLIVDVP------PSVLSLRGNSTVILEQTI 692 Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798 + P + W ++G +I + E NN L D G + C AT Sbjct: 693 NLTCLVRGDPTPAVYWKKDGQIITTA----TLSE-NNRTLTTQAFRVADEGRYACFATNR 747 Query: 4799 AGQVETSAKLVV 4810 AG S + V Sbjct: 748 AGNDSKSILITV 759 Score = 46.0 bits (104), Expect = 8e-04 Identities = 46/183 (25%), Positives = 66/183 (36%), Gaps = 17/183 (9%) Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 P FT+ + + + F G P P I W Q+ S + Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQLSNGSLNVAAVY 643 Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530 E ++ +A + G A+ +A+L+V+ VPPS N V Q Sbjct: 644 NNGSYE--GLYTCLASSEAGMAQSNASLIVD----------VPPSVLSLRGNSTVILEQT 691 Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 + L V G VYW K+G+ I L E+ TL D G+Y C A N Sbjct: 692 INLTCLVRGDPTPAVYWKKDGQ----IITTATLSENNR-TLTTQAFRVADEGRYACFATN 746 Query: 4591 SAG 4593 AG Sbjct: 747 RAG 749 Score = 44.0 bits (99), Expect = 0.003 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 10/91 (10%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKP-LPSGTRYKSTHDFSYVSLD 2834 F H + K+G+++ F C S P +I W +N LP G+ H S SL+ Sbjct: 586 FTRHPRSQTIKQGNHVAFGCAA--SGRPQPRITWLYNGSDALPQGS-----HQLSNGSLN 638 Query: 2835 ITHTYEEDS--GIYTCKATNSKGSATTSGSL 2863 + Y S G+YTC A++ G A ++ SL Sbjct: 639 VAAVYNNGSYEGLYTCLASSEAGMAQSNASL 669 Score = 41.9 bits (94), Expect = 0.012 Identities = 16/50 (32%), Positives = 28/50 (56%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 P F P + T+++G F C +G P+PR+ WL NG+ + ++L+ Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQLS 633 Score = 37.5 bits (83), Expect = 0.26 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 12/116 (10%) Query: 2625 AMNKVPEMFVDTGVQQA---PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKN 2681 A+N V + + V Q P FT H +S + +G HV R P +I W N Sbjct: 564 AVNNVDDKGAVSAVIQVLFEPEFTRHPRS-QTIKQGNHVAFGCAASGRPQP--RITWLYN 620 Query: 2682 GVTLTTGARLKSTFDFGLVTLSINSLRNDDS--GIYTCKATNLLGEAVSTASIKIE 2735 G + A + + +L++ ++ N+ S G+YTC A++ G A S AS+ ++ Sbjct: 621 G----SDALPQGSHQLSNGSLNVAAVYNNGSYEGLYTCLASSEAGMAQSNASLIVD 672 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYRTVYDMGFVS 3888 P+F +S T+++ V F C + P RI W NG LP G + + S Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAASGRPQP--RITWLYNGSDALPQGS-----HQLSNGS 636 Query: 3889 LDILYVYAEDS--GEYICRAVNDFGEDFTKATISCKKLPDII 3928 L++ VY S G Y C A ++ G + A++ P ++ Sbjct: 637 LNVAAVYNNGSYEGLYTCLASSEAGMAQSNASLIVDVPPSVL 678 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 6/93 (6%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT-GSRVKTINDFGFVI 3616 PEFT P + + + F C R+ W +NG L GS + Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAAS--GRPQPRITWLYNGSDALPQGSHQLSNGSLNVAA 641 Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 + G Y+ GLYTC A++ G A + L V Sbjct: 642 VYNNGSYE---GLYTCLASSEAGMAQSNASLIV 671 Score = 34.7 bits (76), Expect = 1.9 Identities = 30/129 (23%), Positives = 53/129 (41%), Gaps = 11/129 (8%) Query: 3112 GTKTTDSGTYSCRATNKW-GQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170 GT D+G Y+C A N + +S ++ + +P FT H ++ + +K G F Sbjct: 551 GTTYADAGNYTCHAVNNVDDKGAVSAVIQVL-----FEPEFTRHPRS-QTIKQGNHVAFG 604 Query: 3171 CTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230 C P +I W +NG + + G + + Y G Y C A ++ Sbjct: 605 CAA--SGRPQPRITWLYNGSDALPQGSHQLSN--GSLNVAAVYNNGSYEGLYTCLASSEA 660 Query: 3231 GEDFTRATI 3239 G + A++ Sbjct: 661 GMAQSNASL 669 Score = 34.7 bits (76), Expect = 1.9 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 8/100 (8%) Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364 I V+ P+F+R + +G +V C G R+ W NG + +++ Sbjct: 578 IQVLFEPEFTRHPRSQTIKQGNHVAFGCAAS--GRPQPRITWLYNGSDALP----QGSHQ 631 Query: 1365 FDYVALDLLSVYPEDS--GVYTCQATNQLGEAVTSCALRV 1402 +L++ +VY S G+YTC A+++ G A ++ +L V Sbjct: 632 LSNGSLNVAAVYNNGSYEGLYTCLASSEAGMAQSNASLIV 671 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F +S T +G + F G P +I WL NG +A + + G +++ Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAAS--GRPQPRITWLYNGS--DALPQGSHQLSNGSLNV 639 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + N G YTC A S G+A++ A L V Sbjct: 640 AAVYNNGSYEGLYTCLASSEAGMAQSNASLIV 671 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 5/91 (5%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P FT + + +G V F C G P RI W +NG A H L++ G + Sbjct: 584 PEFTRHPRSQT-IKQGNHVAFGCAAS--GRPQPRITWLYNGSD-ALPQGSHQLSN-GSLN 638 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 + Y G YTC A+++ G A + A + Sbjct: 639 VAAVYNNGSYEGLYTCLASSEAGMAQSNASL 669 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 5/74 (6%) Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728 R DP + W K+G +TT +T TL+ + R D G Y C ATN G Sbjct: 699 RGDPTPAVYWKKDGQIITT-----ATLSENNRTLTTQAFRVADEGRYACFATNRAGNDSK 753 Query: 2729 TASIKIEDRHWLLG 2742 + I + + LG Sbjct: 754 SILITVTECQQALG 767 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 6/73 (8%) Query: 1738 GDPKLRVEWLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795 G P+ R+ WL NG + S++L+ G + + Y N G YTC A +E G A Sbjct: 609 GRPQPRITWLYNGSDALPQGSHQLSN----GSLNVAAVYNNGSYEGLYTCLASSEAGMAQ 664 Query: 1796 TSSTLFVQSKASL 1808 ++++L V S+ Sbjct: 665 SNASLIVDVPPSV 677 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 5/81 (6%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PP + NS + + G+P P V W K+GQ + + E N+ TL Sbjct: 674 PPSVLSLRGNSTVILEQTINLTCLVRGDPTPAVYWKKDGQIITTATLSE-----NNRTLT 728 Query: 325 VRNTQKSDSGHYTLLAENPNG 345 + + +D G Y A N G Sbjct: 729 TQAFRVADEGRYACFATNRAG 749 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 5/65 (7%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 GD T V W KDG+ + T + LT ++ V D G Y C A N G + S Sbjct: 700 GDPTPAVYWKKDGQIIT-----TATLSENNRTLTTQAFRVADEGRYACFATNRAGNDSKS 754 Query: 997 ANLTI 1001 +T+ Sbjct: 755 ILITV 759 Score = 32.3 bits (70), Expect = 9.9 Identities = 44/188 (23%), Positives = 72/188 (38%), Gaps = 22/188 (11%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGM 3105 PEFT + I +G H +G I W YNG + SH++ G Sbjct: 584 PEFTRHPRSQT-IKQGN--HVAFGCAASGRPQPRITWLYNGSDALPQGSHQLSN----GS 636 Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165 + + + + G Y+C A+++ G A+ + L VD P ++ + Q Sbjct: 637 LNVAAVYNNGSYEGLYTCLASSEAGMAQSNASL-IVDV-----PPSVLSLRGNSTVILEQ 690 Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 + + C V DP + W +GQ + +T + +A D G Y C Sbjct: 691 TINLTCLVR--GDPTPAVYWKKDGQIITTATLSENNRTLTTQAFRVA-----DEGRYACF 743 Query: 3226 AYNKYGED 3233 A N+ G D Sbjct: 744 ATNRAGND 751 >SB_17403| Best HMM Match : I-set (HMM E-Value=0) Length = 671 Score = 64.5 bits (150), Expect = 2e-09 Identities = 79/349 (22%), Positives = 125/349 (35%), Gaps = 54/349 (15%) Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520 T +T L+I + +S + A N G AN + + PP + + Sbjct: 285 TIATGEHLVINNINRSESGDYLCTASN-GVLGSALANATINVQ--------YPPFIEVIS 335 Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580 + +T Q + L TG + W K D+ +L T+ ++ D Sbjct: 336 RIPPITENQTLELYCNATGNPAPAIRWSKGS-----DVT--VLSSGNPLTIRRVQGV--D 386 Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640 G Y C A N G DA ++ + ++I+P + + V EGQ Sbjct: 387 QGVYVCTASNGIG---LDASSTTTVEVL----------VSPVIDVIQP-RSQTVIEGQPA 432 Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700 C G PLP + W +G+ S TL+I+ A + G ++C A N Sbjct: 433 SMYCNATGNPLPNITWTRGNG----------SLVTSGMTLQITAAHRRETGTFRCTADNG 482 Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760 R A KVT Q + + P +D + E P T P I W++ G+ Sbjct: 483 VIRTAXA---KVTLDVQYPPMIHIGP-KDQTLNESNPLSLYCNATGNPSPNITWIKTGS- 537 Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809 Q + G+ L I T D G + C A G + +V Sbjct: 538 -------QNVTVGHGHTLSINKTMTSDEGVYACVAENGVGLPSNATAMV 579 Score = 57.2 bits (132), Expect = 3e-07 Identities = 68/308 (22%), Positives = 105/308 (34%), Gaps = 36/308 (11%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP E I + + + GNP P + W++ V +G+ Sbjct: 328 PPFIEVISRIPPITENQTLELYCNATGNPAPAIRWSKGSDVTVL----------SSGN-P 376 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190 L I+++ D+G Y CTA N G S + S+TV Sbjct: 377 LTIRRVQGVDQGVYVCTASNGIGLDASST------TTVEVLVSPVIDVIQPRSQTVIEGQ 430 Query: 191 YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250 + Y + +T G T + + RE+ T R ++ V Sbjct: 431 PASM-YCNATGNPLPNITWTRGNGSLVTSGMTLQ------ITAAHRRETGTFRCTADNGV 483 Query: 251 QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310 + +L PP I P++ L E +GNP P +TW K G + Sbjct: 484 IRTAXAKVTLDVQYPPMIHIGPKDQTLNESNPLSLYCNATGNPSPNITWIKTGSQ----- 538 Query: 311 KHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN----PNGCIVTSGYLAVESPTESYVQDQ 366 + H H TL + T SD G Y +AEN P+ +A +P +Q Sbjct: 539 --NVTVGHGH-TLSINKTMTSDEGVYACVAENGVGLPSNATAMVTIIAFTAPVFDVIQPN 595 Query: 367 RSQYITDT 374 + TDT Sbjct: 596 TTTNETDT 603 Score = 54.4 bits (125), Expect = 2e-06 Identities = 54/187 (28%), Positives = 72/187 (38%), Gaps = 29/187 (15%) Query: 388 KALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 + L + V Q R T EG+ C TG P P +TW + + + Sbjct: 409 EVLVSPVIDVIQPRSQTVIEGQPASMYCNATGNPLPNITWTRGNGSL-----------VT 457 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAF-QCRLNVIEKEQV-VAPKFVERFSTLNVR 503 L IT ++G C A N TA + L+V + + PK TLN Sbjct: 458 SGMTLQITAAHRRETGTFRCTADNGVIRTAXAKVTLDVQYPPMIHIGPKD----QTLN-- 511 Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563 E P+ L A G P+P ITW K G + T G TL I + SD Y C Sbjct: 512 ESNPLSLYCNATGNPSPNITWIKTGSQNV--------TVGHGHTLSINKTMTSDEGVYAC 563 Query: 564 TAQNVAG 570 A+N G Sbjct: 564 VAENGVG 570 Score = 53.6 bits (123), Expect = 4e-06 Identities = 53/184 (28%), Positives = 72/184 (39%), Gaps = 26/184 (14%) Query: 392 PQFVKVCQD-RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 P F++V +TE + C TG P P + W + V SGN L Sbjct: 328 PPFIEVISRIPPITENQTLELYCNATGNPAPAIRW---------SKGSDVTVLSSGN-PL 377 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREGEPVV 509 I V D GV C A N G A + E +V+P V + + V EG+P Sbjct: 378 TIRRVQGVDQGVYVCTASNGIGLDAS----STTTVEVLVSPVIDVIQPRSQTVIEGQPAS 433 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 + A G P P ITW + ++ T G TL I A + ++CTA N Sbjct: 434 MYCNATGNPLPNITWTRGNGSLV--------TSG--MTLQITAAHRRETGTFRCTADNGV 483 Query: 570 GSTA 573 TA Sbjct: 484 IRTA 487 Score = 53.2 bits (122), Expect = 5e-06 Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 11/126 (8%) Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458 +D+ + E C TG P P +TW Q V H L I S Sbjct: 506 KDQTLNESNPLSLYCNATGNPSPNITWIKTGSQN---------VTVGHGHTLSINKTMTS 556 Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518 D GV CVA N G + + I AP F E + +VL+ A G P Sbjct: 557 DEGVYACVAENGVGLPSNATAMVTIIA--FTAPVFDVIQPNTTTNETDTIVLHCNATGNP 614 Query: 519 TPRITW 524 PRI+W Sbjct: 615 PPRISW 620 Score = 50.4 bits (115), Expect = 3e-05 Identities = 83/379 (21%), Positives = 128/379 (33%), Gaps = 60/379 (15%) Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481 + E++ G P P I+W S + S+ + L IR+V D V+ Sbjct: 340 ITENQTLELYCNATGNPAPAIRW---------SKGSDVTVLSSGNPLTIRRVQGVDQGVY 390 Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541 A N G S+ VE + P + ++ V GQ + TG Sbjct: 391 VCTASNGIGL-DASSTTTVEVL-------VSPVIDVIQPRSQTVIEGQPASMYCNATGNP 442 Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601 ++ W + N L G TL I A+ +++G + C A N Sbjct: 443 LPNITWTRG---------NGSLVTSGM-TLQITAAHRRETGTFRCTADNG---------- 482 Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661 V+ K T PP I KD+ + E + C G P P + W K Sbjct: 483 VIRTAXAK-----VTLDVQYPPMIHIGPKDQTLNESNPLSLYCNATGNPSPNITWIKTGS 537 Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721 Q +TL I++ DEG Y CVA N G + A + A Sbjct: 538 --------QNVTVGHGHTLSINKTMTSDEGVYACVAENGVGLPSNATAMVTIIAFTAPVF 589 Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781 + P + E T P I W ++ ++ Q+ E ++I Sbjct: 590 DVIQP--NTTTNETDTIVLHCNATGNPPPRISW----SISEQSGQRQLTGE----KVIIQ 639 Query: 4782 NTYEEDTGTFTCRATTAAG 4800 N +TG + C A+ G Sbjct: 640 NILRNNTGIYRCTASNGVG 658 Score = 47.6 bits (108), Expect = 2e-04 Identities = 53/220 (24%), Positives = 83/220 (37%), Gaps = 29/220 (13%) Query: 364 QDQRSQYITDTQQRETEERIEISEKALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPE 422 + ++Y + + + + L P V + ++ EG C V G P P Sbjct: 128 ESDHARYRCSIESKMSLSPASVKLNVLVPATVVWISENESFIEGASVTLSCWVKGNPVPY 187 Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 VTW+ + + + S N++ IT + L G C +N G ++ Sbjct: 188 VTWYSPNGTLLHN------ATNSNNNSYTITGLRLDHVGAYRCFTKNVHGT---DDKITY 238 Query: 483 IEKEQVVAPKFVERFSTL-NVREGEPVVLNARAVGTPTPRITWQK--DGVPIIPNPELRI 539 I + P TL V E + + A G P P I+W K GV I L I Sbjct: 239 I----YLPPSITTITPTLQTVNESDITSIYCNASGLPAPSISWSKMSSGVTIATGEHLVI 294 Query: 540 HTDGGASTLDIPRAKASDAAWYQCTAQN-VAGSTATRARL 578 + +I R+++ D Y CTA N V GS A + Sbjct: 295 N--------NINRSESGD---YLCTASNGVLGSALANATI 323 Score = 40.7 bits (91), Expect = 0.028 Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 11/137 (8%) Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494 D H +LV+ +I NV SD C +K + +LNV+ VV Sbjct: 107 DEGH-VLVDADAEATFIIMNVRESDHARYRCSIESKMSLSPASVKLNVLVPATVVWISEN 165 Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554 E F EG V L+ G P P +TW ++ N T+ ++ I + Sbjct: 166 ESFI-----EGASVTLSCWVKGNPVPYVTWYSPNGTLLHNA-----TNSNNNSYTITGLR 215 Query: 555 ASDAAWYQCTAQNVAGS 571 Y+C +NV G+ Sbjct: 216 LDHVGAYRCFTKNVHGT 232 Score = 38.7 bits (86), Expect = 0.11 Identities = 63/304 (20%), Positives = 105/304 (34%), Gaps = 40/304 (13%) Query: 77 IFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQI 136 I +N F +G + ++GNP P V+W L+ N + N T I + Sbjct: 162 ISENESFIEGASVTLSCWVKGNPVPYVTWYSPNGTLLH-NATNSNNNSYT------ITGL 214 Query: 137 GPGDEGEYTCTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQ 194 G Y C +N +G + I +Y+ P +TV T Sbjct: 215 RLDHVGAYRCFTKNVHGTDDKITYIYLPP-----------SITTITPTLQTVNESDI-TS 262 Query: 195 GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIST 254 Y ++++ + + T E+ ++ ++ ES + V S Sbjct: 263 IYCNASGLPAPSISWS-----KMSSGVTIATGEHLVINNINRSESGDYLCTASNGVLGSA 317 Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314 + ++ PP I R + E + +GNP P + W K ++ Sbjct: 318 LANATINVQYPPFIEVISRIPPITENQTLELYCNATGNPAPAIRWSKGS---------DV 368 Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE---SPTESYVQDQRSQYI 371 + L +R Q D G Y A N G + S VE SP +Q RSQ + Sbjct: 369 TVLSSGNPLTIRRVQGVDQGVYVCTASNGIG-LDASSTTTVEVLVSPVIDVIQ-PRSQTV 426 Query: 372 TDTQ 375 + Q Sbjct: 427 IEGQ 430 Score = 37.9 bits (84), Expect = 0.20 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSRYKLT 4160 P + V P + TV EG+ A C TG+P P + W NG+ + +G ++T Sbjct: 414 PVIDVIQPRSQTVIEGQPASMYCNATGNPLPNITWTRGNGSLVTSGMTLQIT 465 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 11/85 (12%) Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433 Q P F + + I I E QT C G+P + W + + SS Sbjct: 326 QYPPFIEVISRIPPITENQTLELYCNA--TGNPAPAIRWSKGSDVTVLSSGNP------- 376 Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458 +TI V+ D+GVY+C ASN +G Sbjct: 377 --LTIRRVQGVDQGVYVCTASNGIG 399 Score = 35.9 bits (79), Expect = 0.80 Identities = 29/114 (25%), Positives = 46/114 (40%), Gaps = 8/114 (7%) Query: 234 VSFRESITKRYVGESDVQIS-TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGN 292 ++ RES RY + ++S + L + P + N EGA + GN Sbjct: 124 MNVRESDHARYRCSIESKMSLSPASVKLNVLVPATVVWISENESFIEGASVTLSCWVKGN 183 Query: 293 PRPRVTWFK-NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345 P P VTW+ NG L N+ T N+ + + + G Y +N +G Sbjct: 184 PVPYVTWYSPNGTLLHNA------TNSNNNSYTITGLRLDHVGAYRCFTKNVHG 231 Score = 35.1 bits (77), Expect = 1.4 Identities = 46/191 (24%), Positives = 64/191 (33%), Gaps = 27/191 (14%) Query: 4622 PPEI--IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679 PP I I P + V E C G P P++ W SK A Sbjct: 242 PPSITTITPTL-QTVNESDITSIYCNASGLPAPSISW---------SKMSSGVTIATGEH 291 Query: 4680 LRISEAFPEDEGDYKCVAYNSA-GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738 L I+ + GDY C A N G A + V P + + + P + E Q Sbjct: 292 LVINNINRSESGDYLCTASNGVLGSALANATINVQYPPFIEVISRIPP-----ITENQTL 346 Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798 + T P I+W + D ++ GN L I D G + C A+ Sbjct: 347 ELYCNATGNPAPAIRWSKGS-------DVTVLSSGN--PLTIRRVQGVDQGVYVCTASNG 397 Query: 4799 AGQVETSAKLV 4809 G +S V Sbjct: 398 IGLDASSTTTV 408 Score = 34.7 bits (76), Expect = 1.9 Identities = 63/287 (21%), Positives = 103/287 (35%), Gaps = 50/287 (17%) Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481 V E + A G PLP I W R N + S L I ++ F Sbjct: 426 VIEGQPASMYCNATGNPLPNITWTRGNGSLVTSG----------MTLQITAAHRRETGTF 475 Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541 A+N G A + ++ + PP + ++ + + L TG Sbjct: 476 RCTADN-GVIRTAXAKVTLDVQ--------YPPMIHIGPKDQTLNESNPLSLYCNATGNP 526 Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601 ++ W+K G + + G +TL I + D G Y CVA N G +A Sbjct: 527 SPNITWIKTGSQ-------NVTVGHG-HTLSINKTMTSDEGVYACVAENGVG-LPSNATA 577 Query: 4602 VVSLPATKDKPKPQTKAANAPP-EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660 +V++ A AP ++I+P + E I C G P P + W Sbjct: 578 MVTI-----------IAFTAPVFDVIQP--NTTTNETDTIVLHCNATGNPPPRISW---- 620 Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707 + + S Q+ T ++ + I + G Y+C A N G ++ Sbjct: 621 SISEQSGQRQL--TGEK--VIIQNILRNNTGIYRCTASNGVGNDVIS 663 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 12/100 (12%) Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231 I+ P F++ +S PP++E + + L C G+P + W G VTV S Sbjct: 323 INVQYPPFIEVISRIPPITENQTLELYC--NATGNPAPAIRW-SKGSDVTVLSSGN---- 375 Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLG-SAHTSAIVRVI 1270 L I D G Y A N +G A ++ V V+ Sbjct: 376 ----PLTIRRVQGVDQGVYVCTASNGIGLDASSTTTVEVL 411 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 10/93 (10%) Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 AP F + + E C TG P P ++W I+++ + L E + Sbjct: 586 APVFDVIQPNTTTNETDTIVLHCNATGNPPPRISWSISEQS-----GQRQLTGEK----V 636 Query: 451 MITNVTLSDSGVVTCVARNKSG-ETAFQCRLNV 482 +I N+ +++G+ C A N G + Q +NV Sbjct: 637 IIQNILRNNTGIYRCTASNGVGNDVISQAHINV 669 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 14/67 (20%) Query: 2672 PNLKIEWFK--NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN-LLGEAVS 2728 P I W K +GVT+ TG L IN++ +SG Y C A+N +LG A++ Sbjct: 271 PAPSISWSKMSSGVTIATGEHLV-----------INNINRSESGDYLCTASNGVLGSALA 319 Query: 2729 TASIKIE 2735 A+I ++ Sbjct: 320 NATINVQ 326 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 11/98 (11%) Query: 1981 GKPIKNAEVTEGHPVHLE--ATLTPVNDPTMRVEWYCN--GRPVQQGHRFKTTYDFGYVA 2036 G + NA + +P +E + + P+ + +E YCN G P R+ D ++ Sbjct: 315 GSALANATINVQYPPFIEVISRIPPITE-NQTLELYCNATGNPAP-AIRWSKGSDVTVLS 372 Query: 2037 ----LDILYAYAEDTGTYMCKATNAVG-EAVTTSSVKV 2069 L I D G Y+C A+N +G +A +T++V+V Sbjct: 373 SGNPLTIRRVQGVDQGVYVCTASNGIGLDASSTTTVEV 410 >SB_57324| Best HMM Match : ig (HMM E-Value=1e-26) Length = 947 Score = 62.9 bits (146), Expect = 6e-09 Identities = 52/196 (26%), Positives = 83/196 (42%), Gaps = 16/196 (8%) Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNV 4525 L I+ V+DS + A N G S L+V K + P F + A + + Sbjct: 477 LRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLK-------VQAPVFRRNIKALRIRL 529 Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585 G ++L G+ + W NGKK++ RN ++ + L I DSG+Y Sbjct: 530 EEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILRG--WVLNIRSLRQSDSGRYT 587 Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI---IEPLKDKIVAEGQAIEF 4642 C+ N G R +VS ++ +P + +NAP I LK+K EG + F Sbjct: 588 CIVKNKHGTIR--RTYIVSPLKSRSTGEPALEPSNAPNGIDINTHLLKNKTAVEGTDVTF 645 Query: 4643 SCKIVGKPLPTVQWYK 4658 +CK V + + W + Sbjct: 646 TCKAVSEVPLSFIWLR 661 Score = 62.9 bits (146), Expect = 6e-09 Identities = 43/125 (34%), Positives = 61/125 (48%), Gaps = 7/125 (5%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQS 3166 L I + DSG Y C+A N +G S+ L + K Q P F +I+ + L++G Sbjct: 477 LRIKNARVKDSGKYLCQAHNSFGMINASITL--IVHLKVQAPVFRRNIKALRIRLEEGSQ 534 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226 C P KI+W+HNG+ +R S R V G+ VL+I + DSG Y C Sbjct: 535 LKLRCHA--NGSPQPKIQWHHNGKKLR-SRRRNHVILRGW-VLNIRSLRQSDSGRYTCIV 590 Query: 3227 YNKYG 3231 NK+G Sbjct: 591 KNKHG 595 Score = 56.0 bits (129), Expect = 7e-07 Identities = 59/260 (22%), Positives = 111/260 (42%), Gaps = 26/260 (10%) Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335 +L+EG+ + + +G+P+P++ W NG++L + ++ +I L +R+ ++SDSG Sbjct: 528 RLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVIL--RGWVLNIRSLRQSDSGR 585 Query: 336 YTLLAENPNGCIVTS---GYLAVESPTESYVQDQRSQYITD--TQQRETEERIE------ 384 YT + +N +G I + L S E ++ + D T + + +E Sbjct: 586 YTCIVKNKHGTIRRTYIVSPLKSRSTGEPALEPSNAPNGIDINTHLLKNKTAVEGTDVTF 645 Query: 385 ----ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440 +SE L+ +++ + T+G + R+ P V R IR+ + Sbjct: 646 TCKAVSEVPLSFIWLRWTPLTNATDGTADQ-PVRILNASDPRV------RLIRESAAYWS 698 Query: 441 LVNESGN--HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498 L ++ + H LM+ NVT D G +CV ++ L V KE + S Sbjct: 699 LADKRASYCHKLMLLNVTKRDQGQYSCVVGGGKEMVSYNVFLTVKPKELRAQDSMYKNTS 758 Query: 499 TLNVREGEPVVLNARAVGTP 518 + GE + A + P Sbjct: 759 SHGKSYGEFEIPLAALIAVP 778 Score = 54.8 bits (126), Expect = 2e-06 Identities = 38/126 (30%), Positives = 53/126 (42%), Gaps = 6/126 (4%) Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR--EG 505 H L I N + DSG C A N G + +I +V AP F L +R EG Sbjct: 475 HHLRIKNARVKDSGKYLCQAHNSFG--MINASITLIVHLKVQAPVFRRNIKALRIRLEEG 532 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 + L A G+P P+I W +G + R H L+I + SD+ Y C Sbjct: 533 SQLKLRCHANGSPQPKIQWHHNGKKL--RSRRRNHVILRGWVLNIRSLRQSDSGRYTCIV 590 Query: 566 QNVAGS 571 +N G+ Sbjct: 591 KNKHGT 596 Score = 49.6 bits (113), Expect = 6e-05 Identities = 49/193 (25%), Positives = 79/193 (40%), Gaps = 8/193 (4%) Query: 3404 MVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL 3463 M+ T + K +APVF + + +R E + + R P K++W+ NGK L Sbjct: 500 MINASITLIVHLKVQAPVFRRNIKALR-IRLEEGSQLKLRCHANGSPQPKIQWHHNGKKL 558 Query: 3464 KAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT---ASMKVQGKRNIIL 3520 + SR R +L I DSG Y C N +G T + +K + L Sbjct: 559 R--SRRRNHVILRGWVLNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPAL 616 Query: 3521 E-SQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTP-SDLILSENSSAHFE 3578 E S P G++ + GT T T +A S P F + L + + +A Sbjct: 617 EPSNAPNGIDINTHLLKNKTAVEGTDVTFTCKAVSEVPLSFIWLRWTPLTNATDGTADQP 676 Query: 3579 CRLIPVNDSSMRV 3591 R++ +D +R+ Sbjct: 677 VRILNASDPRVRL 689 Score = 48.4 bits (110), Expect = 1e-04 Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 10/134 (7%) Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAG----RVTVAAKLKVTQPDQADNLPALTPLR 4728 R+ + + LRI A +D G Y C A+NS G +T+ LKV P N+ AL Sbjct: 470 RSMNGHHLRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLKVQAPVFRRNIKALR--- 526 Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788 I + EG + + +P IQW G + +I G VL I + + D+ Sbjct: 527 -IRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILRG--WVLNIRSLRQSDS 583 Query: 4789 GTFTCRATTAAGQV 4802 G +TC G + Sbjct: 584 GRYTCIVKNKHGTI 597 Score = 47.6 bits (108), Expect = 2e-04 Identities = 48/198 (24%), Positives = 71/198 (35%), Gaps = 25/198 (12%) Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 L I A +DSGKY C A NS G +V L + KA E Sbjct: 477 LRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLKVQAPVFRRNIKALRIRLE------ 530 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 EG ++ C G P P +QW+ K ++ + + + L I D Sbjct: 531 -----EGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILRG--WVLNIRSLRQSDS 583 Query: 4691 GDYKCVAYNSAG---RVTVAAKLKVTQPDQADNLPALTP---------LRDIVVYEGQPA 4738 G Y C+ N G R + + LK + P+ P L++ EG Sbjct: 584 GRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPALEPSNAPNGIDINTHLLKNKTAVEGTDV 643 Query: 4739 QFKTQITSKIKPTIQWLR 4756 F + S++ + WLR Sbjct: 644 TFTCKAVSEVPLSFIWLR 661 Score = 47.6 bits (108), Expect = 2e-04 Identities = 62/252 (24%), Positives = 104/252 (41%), Gaps = 19/252 (7%) Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 QAPVF +K +R+ + + + R G P+ +++W NG + S R + G+V Sbjct: 514 QAPVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLR-SRRRNHVILRGWV 572 Query: 1769 ALNMKYVNPEDSGTYTCRAINELG---EAVTSSTLFVQSKASLQLE-SQHESALQKIQQL 1824 LN++ + DSG YTC N+ G S L +S LE S + + L Sbjct: 573 -LNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPALEPSNAPNGIDINTHL 631 Query: 1825 EDSSRYQRREDVEV---AVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEW 1880 + DV AV++ P FI P + +A RI DP +R+ Sbjct: 632 LKNKTAVEGTDVTFTCKAVSEVPLSFIWLRWTPLTNATDGTADQPVRILNASDPRVRL-- 689 Query: 1881 YFNGKVLQSGHRYRTSNDFGFAA--LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938 + +S + ++ L +L V D G+Y+C ++ L V+ Sbjct: 690 -----IRESAAYWSLADKRASYCHKLMLLNVTKRDQGQYSCVVGGGKEMVSYNVFLTVKP 744 Query: 1939 KESIIRDSQHES 1950 KE +DS +++ Sbjct: 745 KELRAQDSMYKN 756 Score = 46.0 bits (104), Expect = 8e-04 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 7/88 (7%) Query: 388 KALAPQF---VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444 K AP F +K + R + EG + C G P P++ W N +++R + +++ Sbjct: 512 KVQAPVFRRNIKALRIR-LEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILR- 569 Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSG 472 L I ++ SDSG TC+ +NK G Sbjct: 570 --GWVLNIRSLRQSDSGRYTCIVKNKHG 595 Score = 44.8 bits (101), Expect = 0.002 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 2/82 (2%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P F IK+ + EG + + R P+ +I+W+ NGK L S R + G+V L Sbjct: 516 PVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVIL-RGWV-L 573 Query: 3890 DILYVYAEDSGEYICRAVNDFG 3911 +I + DSG Y C N G Sbjct: 574 NIRSLRQSDSGRYTCIVKNKHG 595 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 5/93 (5%) Query: 3691 KPNPPRFTVEIKD-NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749 K P F IK I + EG + C G P +I W HNG+ + R H + Sbjct: 512 KVQAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR 569 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 G++ L+I + D+G YTC NK G+ T Sbjct: 570 -GWV-LNIRSLRQSDSGRYTCIVKNKHGTIRRT 600 Score = 44.0 bits (99), Expect = 0.003 Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 5/86 (5%) Query: 2107 QRPVFLTALTSLE-NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 Q PVF + +L L+EG + C P I W HNG+K+R+ R G Sbjct: 514 QAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR-G 570 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLG 2191 +V L+I DSG Y C NK G Sbjct: 571 WV-LNIRSLRQSDSGRYTCIVKNKHG 595 Score = 43.6 bits (98), Expect = 0.004 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 5/86 (5%) Query: 2640 QAPIFTTHLKSYD-KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698 QAP+F ++K+ +L EG + L P KI+W NG L + R G Sbjct: 514 QAPVFRRNIKALRIRLEEGSQLKLRCHANGSPQP--KIQWHHNGKKLRSRRR-NHVILRG 570 Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLG 2724 V L+I SLR DSG YTC N G Sbjct: 571 WV-LNIRSLRQSDSGRYTCIVKNKHG 595 Score = 42.7 bits (96), Expect = 0.007 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 2/91 (2%) Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE 1628 ++ + QAP+ ++K + I+ + + + R K++W+HN K L+S R Sbjct: 507 LIVHLKVQAPVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRR-NH 565 Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 G+V L+I S DSG YTC N G Sbjct: 566 VILRGWV-LNIRSLRQSDSGRYTCIVKNKHG 595 Score = 40.7 bits (91), Expect = 0.028 Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 6/72 (8%) Query: 3569 LSENSSAHFECRLIPVNDSSM-RVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDA 3627 L E S C N S +++W HNGK L + R I G+V L I + Q D+ Sbjct: 529 LEEGSQLKLRCH---ANGSPQPKIQWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDS 583 Query: 3628 GLYTCKATNRHG 3639 G YTC N+HG Sbjct: 584 GRYTCIVKNKHG 595 Score = 39.5 bits (88), Expect = 0.065 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 10/109 (9%) Query: 3969 KKQPPRFVTQIQS-QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027 K Q P F I++ + L E K C G P K++W NGK L + R I Sbjct: 512 KVQAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR 569 Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI-----KTTGKPGI 4071 G+V +N + DSG Y C N +G ++ ++TG+P + Sbjct: 570 -GWV-LNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPAL 616 Score = 39.5 bits (88), Expect = 0.065 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 5/87 (5%) Query: 650 EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEY 709 EG ++ + R G P KI+W NG+ + + R I R G++ L++ SL DSG Y Sbjct: 531 EGSQL--KLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDSGRY 586 Query: 710 TCRAVSATG-VAETKAVLHVTPRATIE 735 TC + G + T V + R+T E Sbjct: 587 TCIVKNKHGTIRRTYIVSPLKSRSTGE 613 Score = 38.7 bits (86), Expect = 0.11 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 6/87 (6%) Query: 1308 MQAPQFSRALH--NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365 +QAP F R + I EG+ + L C G +++W NGK +++ R Sbjct: 513 VQAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR- 569 Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLG 1392 +V L++ S+ DSG YTC N+ G Sbjct: 570 GWV-LNIRSLRQSDSGRYTCIVKNKHG 595 Score = 38.3 bits (85), Expect = 0.15 Identities = 65/228 (28%), Positives = 89/228 (39%), Gaps = 48/228 (21%) Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDP--HLTID-WF--HNGQ-----KIRAGH 2156 Q+P FL GD +C V +NDP + T WF NG+ K R G Sbjct: 406 QKPKFLKKPKLRYEATVGDSVKLKCLVTGVNDPLFNRTYSVWFSYRNGKTKIVGKPRRGE 465 Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNG 2216 + R G+ L I +DSG Y+C+A N G + TL V H L Q P Sbjct: 466 KSRFRSMNGH-HLRIKNARVKDSGKYLCQAHNSFGMINASITLIV--H----LKVQAPVF 518 Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276 I+ L RI +EE G C P +I Sbjct: 519 RRNIKAL-------RIRLEE--------------------GSQLKLRCHANGSPQP--KI 549 Query: 2277 EFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALG 2324 +++HNGK L+S R H+ G+V L+I+ D+G Y+ N G Sbjct: 550 QWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDSGRYTCIVKNKHG 595 Score = 37.9 bits (84), Expect = 0.20 Identities = 30/148 (20%), Positives = 58/148 (39%), Gaps = 11/148 (7%) Query: 4411 PIFTKKMQPCRVF--EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468 P+F + ++ R+ E Q + +G P P I+W+ +++ + H +L Sbjct: 516 PVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRR--RNHVILRGWVL 573 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF-------TLTAQ 4521 IR + DS + + +N+ GT + + + + R G + P + T + Sbjct: 574 NIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPALEPSNAPNGIDINTHLLK 633 Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549 N G V K P+ WL+ Sbjct: 634 NKTAVEGTDVTFTCKAVSEVPLSFIWLR 661 Score = 37.9 bits (84), Expect = 0.20 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981 +L EG L L + P KI+W+ NGK L R + G+V L++ + + DS Sbjct: 528 RLEEGSQLKL--RCHANGSPQPKIQWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDS 583 Query: 2982 GIYTCKAYNKRG 2993 G YTC NK G Sbjct: 584 GRYTCIVKNKHG 595 Score = 37.5 bits (83), Expect = 0.26 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Query: 768 QRPQFIRPLQDLG-ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG 826 Q P F R ++ L L+EG P +++W+ +G+ + + R I G Sbjct: 514 QAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR-G 570 Query: 827 YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIR-VAARST 867 +V LNI LR D+G YT NK G T + + +RST Sbjct: 571 WV-LNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRST 611 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248 + EG + L C G P +++W HNG+ + SR + + L+I +D+G Sbjct: 529 LEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLR--SRRRNHVILRGWVLNIRSLRQSDSG 584 Query: 1249 EYTVRAVNHLGSAHTSAIV 1267 YT N G+ + IV Sbjct: 585 RYTCIVKNKHGTIRRTYIV 603 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 3/85 (3%) Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100 Q P F +K +E + + + R ++W+ NGK++ S R G+ Sbjct: 514 QAPVFRRNIKALRIRLE-EGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILR-GW 571 Query: 1101 VALDIASVRAEDSGVYTVVARNAAG 1125 V L+I S+R DSG YT + +N G Sbjct: 572 V-LNIRSLRQSDSGRYTCIVKNKHG 595 Score = 36.7 bits (81), Expect = 0.46 Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGK 4179 + +EEG + C G P+P++ W NG + + R + G + +I RQ D+G+ Sbjct: 527 IRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILRG-WVLNIRSLRQSDSGR 585 Query: 4180 IEVI 4183 I Sbjct: 586 YTCI 589 Score = 35.5 bits (78), Expect = 1.1 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 6/84 (7%) Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG---RDST 3368 P K++W +NGKKL R R +L+I + +SG Y C+ NK G R Sbjct: 545 PQPKIQWHHNGKKL--RSRRRNHVILRGWVLNIRSLRQSDSGRYTCIVKNKHGTIRRTYI 602 Query: 3369 KANLKCTSK-ENLILDSQLPRGME 3391 + LK S E + S P G++ Sbjct: 603 VSPLKSRSTGEPALEPSNAPNGID 626 Score = 35.1 bits (77), Expect = 1.4 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 12/95 (12%) Query: 1976 EKPQF-GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW-----YCNGRPV-----QQGH 2024 +KP+F KP E T G V L+ +T VNDP + Y NG+ ++G Sbjct: 406 QKPKFLKKPKLRYEATVGDSVKLKCLVTGVNDPLFNRTYSVWFSYRNGKTKIVGKPRRGE 465 Query: 2025 RFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059 + + G+ L I A +D+G Y+C+A N+ G Sbjct: 466 KSRFRSMNGH-HLRIKNARVKDSGKYLCQAHNSFG 499 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 5/86 (5%) Query: 907 QKPEFKTPIKD-QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965 Q P F+ IK +I ++EG + + R G +++W +G+ + + R G Sbjct: 514 QAPVFRRNIKALRIRLEEG--SQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILR-G 570 Query: 966 YVALTIKSVTVHDAGHYTCRAYNAIG 991 +V L I+S+ D+G YTC N G Sbjct: 571 WV-LNIRSLRQSDSGRYTCIVKNKHG 595 Score = 35.1 bits (77), Expect = 1.4 Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 4/71 (5%) Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845 +EG + C+ S P KI+W N K L S R ++ L+I + DSG Sbjct: 530 EEGSQLKLRCHANGSPQP--KIQWHHNGKKLRS--RRRNHVILRGWVLNIRSLRQSDSGR 585 Query: 2846 YTCKATNSKGS 2856 YTC N G+ Sbjct: 586 YTCIVKNKHGT 596 Score = 35.1 bits (77), Expect = 1.4 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130 G I+W +NGK + + R + G V L I + +DSG Y+C NK G Sbjct: 543 GSPQPKIQWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDSGRYTCIVKNKHG 595 Score = 34.7 bits (76), Expect = 1.9 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 10/95 (10%) Query: 3827 STPPKFITQIK-SHTVEESEGVRFECRVEPKEDP---KLRIEW--YRNGKLLPSGHRYR- 3879 S PKF+ + K + + V+ +C V DP + W YRNGK G R Sbjct: 405 SQKPKFLKKPKLRYEATVGDSVKLKCLVTGVNDPLFNRTYSVWFSYRNGKTKIVGKPRRG 464 Query: 3880 ---TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 M L I +DSG+Y+C+A N FG Sbjct: 465 EKSRFRSMNGHHLRIKNARVKDSGKYLCQAHNSFG 499 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/94 (23%), Positives = 36/94 (38%), Gaps = 6/94 (6%) Query: 72 PIFEQIFK--NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 P+F + K R +G K G+P P + W L + R + Sbjct: 516 PVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKL----RSRRRNHVILRGW 571 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163 L I+ + D G YTC +N++G + + P Sbjct: 572 VLNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSP 605 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 15/105 (14%) Query: 3964 LYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDP--NMKVE-WFF--NGKPLL- 4017 ++ V+ Q P+F+ + + + ++ K +C + V DP N WF NGK + Sbjct: 399 VFGVNYSQKPKFLKKPKLRYEATVGDSVKLKCLVTGVNDPLFNRTYSVWFSYRNGKTKIV 458 Query: 4018 ------HKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGM 4056 K+RF + N +DSG+YLC+A N +GM Sbjct: 459 GKPRRGEKSRFRSMNGHHLRIKN---ARVKDSGKYLCQAHNSFGM 500 Score = 32.7 bits (71), Expect = 7.5 Identities = 14/36 (38%), Positives = 20/36 (55%) Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 L IK+ V D+G Y C+A+N+ G S L + K Sbjct: 477 LRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLK 512 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 5/86 (5%) Query: 2374 QRPVFTQPLQNID-NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432 Q PVF + ++ + ++EG C G P K++W N K + S R G Sbjct: 514 QAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLR-SRRRNHVILRG 570 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458 +V + I +R D G Y C N G Sbjct: 571 WV-LNIRSLRQSDSGRYTCIVKNKHG 595 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 2/64 (3%) Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829 L +K +DSG Y C+A N G S TL V K + ++ AL+ +LE+ S+ Sbjct: 477 LRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLKVQAPVFRRNIKALR--IRLEEGSQ 534 Query: 1830 YQRR 1833 + R Sbjct: 535 LKLR 538 >SB_2157| Best HMM Match : ig (HMM E-Value=9e-19) Length = 603 Score = 62.9 bits (146), Expect = 6e-09 Identities = 65/299 (21%), Positives = 124/299 (41%), Gaps = 38/299 (12%) Query: 4544 DVYWLKNGKKVQPDIRNK------ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 ++ W+K+GK + P R+ +L + T L++ + +G Y C+ + Sbjct: 87 EIRWMKDGKLLDPRRRSTEYRDYAVLRDGNTSILMLRNVSTRHTGGYRCITSRAGKHPLS 146 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 +C +++ + ++P+ K + PL+ I+ Q F C G+P P + W Sbjct: 147 FTQCFLNVTLS-ERPRILRKPLHL---FTPPLQ--ILTRDQPQTFHCYADGQPAPRLAWL 200 Query: 4658 KGDKLI-KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR------VTVAAKL 4710 K D +I + K +++++ A L I A G+Y C+A N GR ++ ++ Sbjct: 201 KDDHVIGENQKGYRLAKRARGLDLTIMLAQANSGGNYTCLAVNRLGRAEYHIWAVLSGEI 260 Query: 4711 KVTQPDQADNLPALTP--------LRDIVVYEGQPAQFKTQIT--SKIKPTIQWLREGAL 4760 V + ++P L ++V G PA + T K+ W+ G + Sbjct: 261 NVKHIANIVEVEHISPEKPEVTAELPVVLVRFGHPANLTCRSTHAPKVYTISYWMYGGKV 320 Query: 4761 IPETPDFQMI------HEGNNAVLL---IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 + D I +G N+++L + N EE G ++C T G +LV+ Sbjct: 321 VENMGDEYSITRTWGKGKGANSLMLNLQVRNVTEETAGNYSCIVQTHIGPGSADTRLVI 379 Score = 43.6 bits (98), Expect = 0.004 Identities = 40/150 (26%), Positives = 65/150 (43%), Gaps = 6/150 (4%) Query: 427 INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV-ARNKSGETAF-QCRLNVIE 484 ++ R+ +Y ++ + LM+ NV+ +G C+ +R +F QC LNV Sbjct: 97 LDPRRRSTEYRDYAVLRDGNTSILMLRNVSTRHTGGYRCITSRAGKHPLSFTQCFLNVTL 156 Query: 485 KEQV-VAPKFVERFST-LNV-REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIH 540 E+ + K + F+ L + +P + A G P PR+ W KD I N + R+ Sbjct: 157 SERPRILRKPLHLFTPPLQILTRDQPQTFHCYADGQPAPRLAWLKDDHVIGENQKGYRLA 216 Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 L I A+A+ Y C A N G Sbjct: 217 KRARGLDLTIMLAQANSGGNYTCLAVNRLG 246 Score = 37.1 bits (82), Expect = 0.35 Identities = 31/130 (23%), Positives = 49/130 (37%), Gaps = 14/130 (10%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 +T + F C G+P P + W +D I ++ L + L I + G Sbjct: 177 LTRDQPQTFHCYADGQPAPRLAWLKDDHVIGENQKGYRLAKRARGLDLTIMLAQANSGGN 236 Query: 463 VTCVARNK------------SGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPV 508 TC+A N+ SGE + N++E E + P+ + VR G P Sbjct: 237 YTCLAVNRLGRAEYHIWAVLSGEINVKHIANIVEVEHISPEKPEVTAELPVVLVRFGHPA 296 Query: 509 VLNARAVGTP 518 L R+ P Sbjct: 297 NLTCRSTHAP 306 Score = 36.3 bits (80), Expect = 0.61 Identities = 45/225 (20%), Positives = 81/225 (36%), Gaps = 31/225 (13%) Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR-YRTSNDFGFAALDILTVYGEDS 1914 L+ Q + C + P P R+ W + V+ + YR + L I+ Sbjct: 177 LTRDQPQTFHCYADGQPAP--RLAWLKDDHVIGENQKGYRLAKRARGLDLTIMLAQANSG 234 Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974 G YTC A+N LG+A I + + ++ +H + + +++++ Sbjct: 235 GNYTCLAVNRLGRAEYHIWAVLSGEINV----KHIANIVEVEHISP-------------- 276 Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFG 2033 EKP+ + V GHP +L T W G+ V+ G + T +G Sbjct: 277 -EKPEVTAELPVVLVRFGHPANLTCRSTHAPKVYTISYWMYGGKVVENMGDEYSITRTWG 335 Query: 2034 --------YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 + L + E G Y C +G + + +D Sbjct: 336 KGKGANSLMLNLQVRNVTEETAGNYSCIVQTHIGPGSADTRLVID 380 Score = 32.7 bits (71), Expect = 7.5 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 3/60 (5%) Query: 97 GNPTPVVSWTRKKAPLVECNK-YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155 G P P ++W + + E K Y + + D+++++ Q G G YTC A N+ G A Sbjct: 191 GQPAPRLAWLKDDHVIGENQKGYRLAKRARGLDLTIMLAQANSG--GNYTCLAVNRLGRA 248 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 1/56 (1%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGY-VSLNIMHLRAEDAGSYTVRAVNKLGEA 854 P R+ W KD I + + + + L IM +A G+YT AVN+LG A Sbjct: 193 PAPRLAWLKDDHVIGENQKGYRLAKRARGLDLTIMLAQANSGGNYTCLAVNRLGRA 248 >SB_20844| Best HMM Match : Ion_trans (HMM E-Value=0) Length = 2675 Score = 62.9 bits (146), Expect = 6e-09 Identities = 49/170 (28%), Positives = 73/170 (42%), Gaps = 10/170 (5%) Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 +C+ G P P+V W KG L+ S ++ TLRI +A EDEG Y C A N G Sbjct: 707 TCRAEGNPEPSVGWKKG--LLPVSSLGPRYEILEDGTLRIEQAMIEDEGTYSCYATNFKG 764 Query: 4703 RV-TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761 + T A L+V P ++ P + V G+P Q + K P +W ++ LI Sbjct: 765 PLQTRTANLRVVVPVTV----SMIPRDEHEVSVGEPLTIYCQFSGKPTPFNRWYKDSQLI 820 Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 + I G + I + D G + C+A G+ + VK Sbjct: 821 LNGNERISISPGQ---ISIKSVLPSDAGLYECQAIHDYGRAADFVTIKVK 867 Score = 51.2 bits (117), Expect = 2e-05 Identities = 57/192 (29%), Positives = 79/192 (41%), Gaps = 25/192 (13%) Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQP-DIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589 V L + G V W K V R +ILE DGT L I +A +D G Y C A Sbjct: 704 VLLTCRAEGNPEPSVGWKKGLLPVSSLGPRYEILE-DGT--LRIEQAMIEDEGTYSCYAT 760 Query: 4590 NSAGEARC-DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648 N G + A V +P T + P + V+ G+ + C+ G Sbjct: 761 NFKGPLQTRTANLRVVVPVTVS---------------MIPRDEHEVSVGEPLTIYCQFSG 805 Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT--V 4706 KP P +WYK +LI ++S + + + I P D G Y+C A + GR V Sbjct: 806 KPTPFNRWYKDSQLILNGNE-RISISPGQ--ISIKSVLPSDAGLYECQAIHDYGRAADFV 862 Query: 4707 AAKLKVTQPDQA 4718 K+K QP A Sbjct: 863 TIKVKGDQPSLA 874 Score = 49.2 bits (112), Expect = 8e-05 Identities = 59/236 (25%), Positives = 87/236 (36%), Gaps = 16/236 (6%) Query: 349 TSGYLAVESP-TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407 TS Y ++ ++Y D ++ T R +++ E+A + D D T + Sbjct: 541 TSDYRPTDNKEADNYTPDNQTTNNRATDNRASDDYTTNDEEANNYKTNNNAPDDDTTNHE 600 Query: 408 MTRFDCRVTGRPYPEVT--WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 T D Y + + ND + D+Y N++ NH N T DS Sbjct: 601 ATDNDAPDHNTTYYDTPDDYTTNDEEA-DNYKTN---NDTTNHEAPHHNTTDDDSPDHNT 656 Query: 466 VARNKSGETA---FQCRLNVIEKEQVVAPKFVE--RFSTLNVREGEPVVLNARAVGTPTP 520 + + F C L +K V + E R V+L RA G P P Sbjct: 657 TGNDAPDDYTTNDFPCNLREADKASDVTDREAEANRAGEDPTFVRSQVLLTCRAEGNPEP 716 Query: 521 RITWQKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575 + W+K +P+ P I DG TL I +A D Y C A N G TR Sbjct: 717 SVGWKKGLLPVSSLGPRYEILEDG---TLRIEQAMIEDEGTYSCYATNFKGPLQTR 769 Score = 49.2 bits (112), Expect = 8e-05 Identities = 46/161 (28%), Positives = 60/161 (37%), Gaps = 9/161 (5%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 CR G P P V W + + + E G L I + D G +C A N G Sbjct: 708 CRAEGNPEPSVGWKKGLLPV-SSLGPRYEILEDGT--LRIEQAMIEDEGTYSCYATNFKG 764 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532 Q R + V + R V GEP+ + + G PTP W KD +I Sbjct: 765 P--LQTRTANLRVVVPVTVSMIPR-DEHEVSVGEPLTIYCQFSGKPTPFNRWYKDS-QLI 820 Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 N RI G + I SDA Y+C A + G A Sbjct: 821 LNGNERISISPG--QISIKSVLPSDAGLYECQAIHDYGRAA 859 Score = 39.1 bits (87), Expect = 0.086 Identities = 42/176 (23%), Positives = 74/176 (42%), Gaps = 19/176 (10%) Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKN-SPDFQIHTFSTKSILIIRQVFVEDSAVF 4481 F Q +G P P + W + P+ + P ++I T L I Q +ED + Sbjct: 699 FVRSQVLLTCRAEGNPEPSVGWKKGLLPVSSLGPRYEILEDGT---LRIEQAMIEDEGTY 755 Query: 4482 AAVAEN-RGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN-VTSGQLVRLDTKVTG 4539 + A N +G +ANL V +VP + ++ ++ + V+ G+ + + + +G Sbjct: 756 SCYATNFKGPLQTRTANLRV----------VVPVTVSMIPRDEHEVSVGEPLTIYCQFSG 805 Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595 W K+ + + +I G + I P D+G YEC AI+ G A Sbjct: 806 KPTPFNRWYKDSQLILNG-NERISISPGQIS--IKSVLPSDAGLYECQAIHDYGRA 858 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 5/84 (5%) Query: 3839 HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAED 3898 H V E + C+ K P R WY++ +L+ +G+ R G +S I V D Sbjct: 789 HEVSVGEPLTIYCQFSGKPTPFNR--WYKDSQLILNGNE-RISISPGQIS--IKSVLPSD 843 Query: 3899 SGEYICRAVNDFGEDFTKATISCK 3922 +G Y C+A++D+G TI K Sbjct: 844 AGLYECQAIHDYGRAADFVTIKVK 867 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 G PTP W + ++ N+ R + G +S IK + P D G Y C A + YG A Sbjct: 805 GKPTPFNRWYKDSQLILNGNE---RISISPGQIS--IKSVLPSDAGLYECQAIHDYGRAA 859 Query: 157 CSVYIQPEG 165 V I+ +G Sbjct: 860 DFVTIKVKG 868 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 4/88 (4%) Query: 259 SLGPVSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317 +L V P ++ PR+ ++ G Q SG P P W+K+ Q ++N N+ I+ Sbjct: 772 NLRVVVPVTVSMIPRDEHEVSVGEPLTIYCQFSGKPTPFNRWYKDSQLILNGNERISISP 831 Query: 318 HNHTTLRVRNTQKSDSGHYTLLAENPNG 345 + +++ SD+G Y A + G Sbjct: 832 GQ---ISIKSVLPSDAGLYECQAIHDYG 856 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914 ++S G+ C+ P P R WY + +++ +G+ R S G + I +V D+ Sbjct: 790 EVSVGEPLTIYCQFSGKPTPFNR--WYKDSQLILNGNE-RISISPG--QISIKSVLPSDA 844 Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKE 1940 G Y C+AI++ G+A + + V+ + Sbjct: 845 GLYECQAIHDYGRAADFVTIKVKGDQ 870 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 4/60 (6%) Query: 94 KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 + GNP P V W K L+ + RY E D +L I+Q DEG Y+C A N G Sbjct: 709 RAEGNPEPSVGW---KKGLLPVSSLGPRY-EILEDGTLRIEQAMIEDEGTYSCYATNFKG 764 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 4/92 (4%) Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 + +V+ G+ C+ +G+P P W+ D Q+ + N +I ++ + I +V SD Sbjct: 788 EHEVSVGEPLTIYCQFSGKPTPFNRWY-KDSQLILNGNERISISPG---QISIKSVLPSD 843 Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491 +G+ C A + G A + V + +AP Sbjct: 844 AGLYECQAIHDYGRAADFVTIKVKGDQPSLAP 875 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 3/61 (4%) Query: 3593 WFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652 W+ + + +L G+ +I+ + I V DAGLY C+A + +G A ++VKG Sbjct: 813 WYKDSQLILNGNERISISPGQ---ISIKSVLPSDAGLYECQAIHDYGRAADFVTIKVKGD 869 Query: 3653 Q 3653 Q Sbjct: 870 Q 870 Score = 33.1 bits (72), Expect = 5.7 Identities = 13/35 (37%), Positives = 21/35 (60%) Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514 + I P D+G Y C+A ++YG A ++KV+G Sbjct: 834 ISIKSVLPSDAGLYECQAIHDYGRAADFVTIKVKG 868 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 2795 CNVEPSRDPTLKIEWFFNNKPLPS-GTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNS 2853 C E + +P+ + W P+ S G RY+ D + L I ED G Y+C ATN Sbjct: 708 CRAEGNPEPS--VGWKKGLLPVSSLGPRYEILEDGT---LRIEQAMIEDEGTYSCYATNF 762 Query: 2854 KGSATT 2859 KG T Sbjct: 763 KGPLQT 768 >SB_27122| Best HMM Match : I-set (HMM E-Value=1.9e-39) Length = 378 Score = 61.7 bits (143), Expect = 1e-08 Identities = 60/254 (23%), Positives = 96/254 (37%), Gaps = 30/254 (11%) Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAG------EARCDAECVVSLPATKDKPKPQTKAAN 4620 G+ TL +L+ +G Y+C A N + + +C ++ D T Sbjct: 58 GSATLSLLKIQQHQAGVYQCQATNDVRRGPITHDITINVQCEYNVICYPDIFSVSTLTEQ 117 Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680 PPEI P+++ + G+ I +C + G P P+V W K ++ Sbjct: 118 DPPEIT-PIQNTTIRAGETITLTCAVAGNPTPSVSWSKAGS----------GQSTGGNVF 166 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740 + A D G Y C A N T K T L+ D V E + Sbjct: 167 NEAGATKADTGQYVCTAVNIVSGNT-QTKTASTYVIVKYKPSILSKSPDQTVNETTGSLK 225 Query: 4741 KTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799 T I+ PT+ W R+G ++ T ++ N+ + GT+TC AT A Sbjct: 226 LTCISDGYPSPTVTWSRDGVVVSRT----SVYHSNSVT-------RSEAGTYTCTATNAM 274 Query: 4800 GQVETSAKLVVKSK 4813 G T+ ++ V K Sbjct: 275 GSDTTTVQVTVNYK 288 Score = 53.6 bits (123), Expect = 4e-06 Identities = 50/194 (25%), Positives = 75/194 (38%), Gaps = 34/194 (17%) Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458 + RDV E K C +G P P VTW +N + + + +G+ L + + Sbjct: 18 RSRDVAEDKDFSITCSASGHPAPNVTW-VNKT------SGSPVAHGTGSATLSLLKIQQH 70 Query: 459 DSGVVTCVARN--KSGETAF------QCRLNVIEKEQVVA--------PKFVERFSTLNV 502 +GV C A N + G QC NVI + + P + + Sbjct: 71 QAGVYQCQATNDVRRGPITHDITINVQCEYNVICYPDIFSVSTLTEQDPPEITPIQNTTI 130 Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562 R GE + L G PTP ++W K G G + + A +D Y Sbjct: 131 RAGETITLTCAVAGNPTPSVSWSKAG----------SGQSTGGNVFNEAGATKADTGQYV 180 Query: 563 CTAQN-VAGSTATR 575 CTA N V+G+T T+ Sbjct: 181 CTAVNIVSGNTQTK 194 Score = 51.6 bits (118), Expect = 2e-05 Identities = 60/223 (26%), Positives = 92/223 (41%), Gaps = 31/223 (13%) Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT-RFD 412 A ++ T YV + +TQ + + + K P + D+ V E + + Sbjct: 171 ATKADTGQYVCTAVNIVSGNTQTKTASTYVIVKYK---PSILSKSPDQTVNETTGSLKLT 227 Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C G P P VTW RD ++ S H+ +VT S++G TC A N G Sbjct: 228 CISDGYPSPTVTWS------RDGV---VVSRTSVYHS---NSVTRSEAGTYTCTATNAMG 275 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN--ARAVGTPTPRITWQKDG-V 529 ++ V K ++V+ ST N + VL+ + G P+P+ITW K G Sbjct: 276 SDTTTVQVTVNYKPEMVS-------STTNTSSWDRNVLSLQCKVRGVPSPQITWYKPGDQ 328 Query: 530 PIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQNVAGS 571 PI + G S L + + A D Y+C A N+ GS Sbjct: 329 PITAG----VSPISGGSQLQVTTTQDAGDYGQYKCWASNLLGS 367 Score = 46.0 bits (104), Expect = 8e-04 Identities = 67/293 (22%), Positives = 112/293 (38%), Gaps = 44/293 (15%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 PP T QN + +G+ + L V G V W K G + E G Sbjct: 119 PPEIT-PIQNTTIRAGETITLTCAVAGNPTPSVSWSKAGS--GQSTGGNVFNEAG----- 170 Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632 A D+G+Y C A+N +VS T+ K P I+ D+ Sbjct: 171 ---ATKADTGQYVCTAVN-----------IVS-GNTQTKTASTYVIVKYKPSILSKSPDQ 215 Query: 4633 IVAEGQ-AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691 V E +++ +C G P PTV W + D ++ +SRT+ ++ ++ + + G Sbjct: 216 TVNETTGSLKLTCISDGYPSPTVTWSR-DGVV-------VSRTSVYHSNSVTRS---EAG 264 Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751 Y C A N+ G T ++ V + ++ + ++ + ++ P Sbjct: 265 TYTCTATNAMGSDTTTVQVTVNYKPE-----MVSSTTNTSSWDRNVLSLQCKVRGVPSPQ 319 Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE-DTGTFTCRATTAAGQVE 4803 I W + G P T I G+ L + T + D G + C A+ G VE Sbjct: 320 ITWYKPGDQ-PITAGVSPISGGSQ--LQVTTTQDAGDYGQYKCWASNLLGSVE 369 Score = 43.6 bits (98), Expect = 0.004 Identities = 46/190 (24%), Positives = 74/190 (38%), Gaps = 28/190 (14%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P + Q+ + G+ C V G P P V+W + + NE+G Sbjct: 119 PPEITPIQNTTIRAGETITLTCAVAGNPTPSVSW---SKAGSGQSTGGNVFNEAG----- 170 Query: 452 ITNVTLSDSGVVTCVARN-KSGETAFQCRLN--VIEKEQVVAPKFVERFSTLNVREGEPV 508 T +D+G C A N SG T + +++ + + K ++ T+N G + Sbjct: 171 ---ATKADTGQYVCTAVNIVSGNTQTKTASTYVIVKYKPSILSKSPDQ--TVNETTGS-L 224 Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568 L + G P+P +TW +DGV + S S+A Y CTA N Sbjct: 225 KLTCISDGYPSPTVTWSRDGVVV-----------SRTSVYHSNSVTRSEAGTYTCTATNA 273 Query: 569 AGSTATRARL 578 GS T ++ Sbjct: 274 MGSDTTTVQV 283 Score = 38.3 bits (85), Expect = 0.15 Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 14/118 (11%) Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175 +++GTY+C ATN G +V++ + KP + N D +C V Sbjct: 261 SEAGTYTCTATNAMGSDTTTVQV-----TVNYKPEMVSSTTNTSSW-DRNVLSLQCKVRG 314 Query: 3176 VDDPDMKIEWYHNG-QPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231 V P +I WY G QP+ + + +S G L + TQ+ D G+Y C A N G Sbjct: 315 VPSP--QITWYKPGDQPI--TAGVSPIS--GGSQLQVTTTQDAGDYGQYKCWASNLLG 366 Score = 37.9 bits (84), Expect = 0.20 Identities = 16/47 (34%), Positives = 29/47 (61%) Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEK 1019 SVT +AG YTC A NA+G TT+ +T+ K ++++ + + ++ Sbjct: 257 SVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303 Score = 37.9 bits (84), Expect = 0.20 Identities = 16/31 (51%), Positives = 22/31 (70%) Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794 +AG YTC ATN GS TTT ++T + K ++V Sbjct: 262 EAGTYTCTATNAMGSDTTTVQVTVNYKPEMV 292 Score = 36.3 bits (80), Expect = 0.61 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 10/108 (9%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897 + +AP F L+ ++E + C +P PN V W K S + T Sbjct: 4 IVSTEAPAFNPPLDRSRDVAEDKDFSITCSASGHPAPN--VTWV--NKTSGSPVAHGT-- 57 Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNL--GQAVSSIRLNVQSKESII 1943 G A L +L + +G Y C+A N++ G I +NVQ + ++I Sbjct: 58 --GSATLSLLKIQQHQAGVYQCQATNDVRRGPITHDITINVQCEYNVI 103 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 13/91 (14%) Query: 1166 MYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR 1225 ++ + +++ P + P+ N + G+ I L C + G+PT V W G + G Sbjct: 108 IFSVSTLTEQDPPEITPIQNTT-IRAGETITLTCAVA--GNPTPSVSWSKAGSGQSTGGN 164 Query: 1226 FKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256 + + G AT ADTG+Y AVN Sbjct: 165 --VFNEAG--------ATKADTGQYVCTAVN 185 Score = 35.9 bits (79), Expect = 0.80 Identities = 14/48 (29%), Positives = 26/48 (54%) Query: 2705 NSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDR 2752 NS+ ++G YTC ATN +G +T + + + ++ + + S DR Sbjct: 256 NSVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL-KKIQELEKYER--PKP-IE 2101 + GTY C ATNA+G TT V V+ K + T + + + L+ R P P I Sbjct: 262 EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDRNVLSLQCKVRGVPSPQIT 321 Query: 2102 EEQPGQRPV 2110 +PG +P+ Sbjct: 322 WYKPGDQPI 330 Score = 33.9 bits (74), Expect = 3.2 Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 8/85 (9%) Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430 V+ + P F PL ++ E + C G P V W + +S H Sbjct: 5 VSTEAPAFNPPLDRSRDVAEDKDFSITCSAS--GHPAPNVTW------VNKTSGSPVAHG 56 Query: 2431 FGYVSMTISHVRDEDEGVYMCRASN 2455 G ++++ ++ GVY C+A+N Sbjct: 57 TGSATLSLLKIQQHQAGVYQCQATN 81 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 4/83 (4%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P++ N+ + Q ++ G P P++TW+K G + I + I + L+V Sbjct: 289 PEMVSSTTNTSSWDRNVLSLQCKVRGVPSPQITWYKPGDQPITAGVSPI---SGGSQLQV 345 Query: 326 RNTQKS-DSGHYTLLAENPNGCI 347 TQ + D G Y A N G + Sbjct: 346 TTTQDAGDYGQYKCWASNLLGSV 368 Score = 33.5 bits (73), Expect = 4.3 Identities = 13/42 (30%), Positives = 25/42 (59%) Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQ 1554 ++G YTC A N +G+D + ++T ++V ST N + ++ Sbjct: 262 EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/117 (21%), Positives = 49/117 (41%), Gaps = 13/117 (11%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897 V V P +++ T S C + YP P V W +G V+ Y +++ Sbjct: 200 VIVKYKPSILSKSPDQTVNETTGSLKLTCISDGYPSPT--VTWSRDGVVVSRTSVYHSNS 257 Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954 V ++G YTC A N +G +++++ V K ++ + + S+ ++ Sbjct: 258 -----------VTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303 Score = 32.7 bits (71), Expect = 7.5 Identities = 14/47 (29%), Positives = 26/47 (55%) Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK 1420 SV ++G YTC ATN +G T+ + V K +++ + + S ++ Sbjct: 257 SVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303 >SB_33752| Best HMM Match : I-set (HMM E-Value=3.7e-15) Length = 783 Score = 61.3 bits (142), Expect = 2e-08 Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 1/119 (0%) Query: 369 QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428 Q + D + E EE E + P FV D +V EG+ D V Y E+ W+ N Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKAEHY-ELEWYKN 365 Query: 429 DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487 + + + E G HAL+I V D G CVA N +G T L V E+E+ Sbjct: 366 AVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEE 424 Score = 55.2 bits (127), Expect = 1e-06 Identities = 45/149 (30%), Positives = 65/149 (43%), Gaps = 7/149 (4%) Query: 3673 QKLEETLHKREEITIEDE-KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731 Q LE+ + EE E E + +PP F E D I+V EG V D V+ ++W Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTD-IEVKEGENVTLDVEVKA---EHYELEW 362 Query: 3732 FHNGRPFATGSRVH-TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT-CSA 3789 + N G RV T + G AL I+ + D GEY C A N G T +T Sbjct: 363 YKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEE 422 Query: 3790 KRDIVLESQLPQGMSGEKIKELERGRISD 3818 + + E + + EK+ +L + I D Sbjct: 423 EEESESEDETDEEFYEEKVVKLRKEHIED 451 Score = 52.8 bits (121), Expect = 7e-06 Identities = 40/157 (25%), Positives = 71/157 (45%), Gaps = 7/157 (4%) Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881 Q LED + + E+ E P ++ EG++ + ++ + +EWY Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKA---EHYELEWY 363 Query: 1882 FNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 N + G R R TS + G AL I V +D GEY C A+N+ G+ + L V +E Sbjct: 364 KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423 Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK 1977 +S+ E ++ Y E + ++ +D + +E+ Sbjct: 424 ---EESESEDETDEEFYEEKVVKLRKEHIEDFYALEE 457 Score = 52.4 bits (120), Expect = 9e-06 Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 4/134 (2%) Query: 4501 EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN 4560 EE+ + G PP F ++ V G+ V LD +V + ++ W KN V R Sbjct: 319 EEEESEPEGD--PPVFVHEFTDIEVKEGENVTLDVEVK-AEHYELEWYKNAVDVVEGGRV 375 Query: 4561 KILE-EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619 + E G + L+I E D G+Y CVA+N AG C V+ + + + +T Sbjct: 376 RFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEEESESEDETDEE 435 Query: 4620 NAPPEIIEPLKDKI 4633 ++++ K+ I Sbjct: 436 FYEEKVVKLRKEHI 449 Score = 51.6 bits (118), Expect = 2e-05 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 8/123 (6%) Query: 2081 DEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPH 2140 ++Q L+ I E E+ E E E G PVF+ T +E +KEG+ + V+ H Sbjct: 305 EQQDLEDIAEEEEEEEE---ESEPEGDPPVFVHEFTDIE-VKEGENVTLDVEVKA---EH 357 Query: 2141 LTIDWFHNGQKIRAGHRYR-TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199 ++W+ N + G R R T+ + G AL I +D G Y C A N G L Sbjct: 358 YELEWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNL 417 Query: 2200 KVA 2202 VA Sbjct: 418 TVA 420 Score = 51.2 bits (117), Expect = 2e-05 Identities = 36/117 (30%), Positives = 54/117 (46%), Gaps = 6/117 (5%) Query: 3398 QTLEDSMVRRKDTSVEEE-KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456 Q LED ++ E E +G PVF ++IE ++EGEN + + + ++EW Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIE-VKEGENVTLDVEVKAE---HYELEW 362 Query: 3457 YWNGKSLKAGSRFR-TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 Y N + G R R T + G L I +D GEY C A N+ G ++ V Sbjct: 363 YKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV 419 Score = 50.8 bits (116), Expect = 3e-05 Identities = 27/110 (24%), Positives = 54/110 (49%), Gaps = 2/110 (1%) Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD-KLIKPSK 4667 +++ + +++ PP + D V EG+ + ++ + ++WYK +++ + Sbjct: 316 EEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKAEHYE-LEWYKNAVDVVEGGR 374 Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717 S ++ L I E +D+G+Y CVA N AGR T A L V + ++ Sbjct: 375 VRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEE 424 Score = 50.4 bits (115), Expect = 3e-05 Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 5/110 (4%) Query: 3270 QQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329 +++ S P +PP F+ + D+ ++ EG++ + V V ++EW+ N + G Sbjct: 318 EEEEESEPEGDPPVFVHEFTDI-EVKEGENVTLD---VEVKAEHYELEWYKNAVDVVEGG 373 Query: 3330 RYR-TFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378 R R T + G L I +++ GEY CVA N GR + NL +E Sbjct: 374 RVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423 Score = 49.6 bits (113), Expect = 6e-05 Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 5/111 (4%) Query: 2481 PEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSL 2540 P + ++ + + E EE + E + P+F T E+ EG++ + V V Sbjct: 303 PGEQQDLEDIAEEEEEEEEESEPEGDPPVFVHEFTD-IEVKEGENVTLD---VEVKAEHY 358 Query: 2541 RFEWYINGVELKMGSRFR-TTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 EWY N V++ G R R T+ + G L I V +D G Y C A+N AG Sbjct: 359 ELEWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAG 409 Score = 48.8 bits (111), Expect = 1e-04 Identities = 40/154 (25%), Positives = 63/154 (40%), Gaps = 6/154 (3%) Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080 Q LED + + EEE + P ++ EG++ + V+ + +EWY Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKAEH---YELEWY 363 Query: 1081 FNGKQITSANRIQ-TYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV--ET 1137 N + R++ T + G AL I V +D G Y VA N AG + ++TV E Sbjct: 364 KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423 Query: 1138 RSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEE 1171 S YE+ + +E Y +EE Sbjct: 424 EESESEDETDEEFYEEKVVKLRKEHIEDFYALEE 457 Score = 48.4 bits (110), Expect = 1e-04 Identities = 32/126 (25%), Positives = 51/126 (40%), Gaps = 2/126 (1%) Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441 I E ++E A+ +E E PP+F + V E E +VE E L Sbjct: 301 IVPGEQQDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKAEHYEL 360 Query: 4442 IKWYRENFPIKNSPDFQIHT-FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500 +WY+ + + + K L+I +V +D + VA N G C+ NL V Sbjct: 361 -EWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV 419 Query: 4501 EEKRRQ 4506 E+ + Sbjct: 420 AEEEEE 425 Score = 48.0 bits (109), Expect = 2e-04 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 5/121 (4%) Query: 2617 EQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKI 2676 EQ L++ A + E P+F + + EG++V L+ +V+ + ++ Sbjct: 305 EQQDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIE-VKEGENVTLDVEVKAE---HYEL 360 Query: 2677 EWFKNGVTLTTGARLKSTF-DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 EW+KN V + G R++ T + G L I + +DD G Y C A N G ++ + Sbjct: 361 EWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVA 420 Query: 2736 D 2736 + Sbjct: 421 E 421 Score = 47.2 bits (107), Expect = 3e-04 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 2/89 (2%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT-DGGASTLD 549 P FV F+ + V+EGE V L+ V + W K+ V ++ +R + +GG L Sbjct: 330 PVFVHEFTDIEVKEGENVTLDVE-VKAEHYELEWYKNAVDVVEGGRVRFTSGEGGKHALV 388 Query: 550 IPRAKASDAAWYQCTAQNVAGSTATRARL 578 I + D Y C A N AG T L Sbjct: 389 IEEVEDDDQGEYCCVAMNDAGRTTCAGNL 417 Score = 46.4 bits (105), Expect = 6e-04 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 5/107 (4%) Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865 + ++++ + + EP PP F+ + V+E E V + V+ + +EW Sbjct: 307 QDLEDIAEEEEEEEEESEP-EGDPPVFVHEFTDIEVKEGENVTLDVEVKAEH---YELEW 362 Query: 3866 YRNGKLLPSGHRYR-TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 Y+N + G R R T + G +L I V +D GEY C A+ND G Sbjct: 363 YKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAG 409 Score = 46.4 bits (105), Expect = 6e-04 Identities = 37/147 (25%), Positives = 64/147 (43%), Gaps = 6/147 (4%) Query: 1691 LEDTSKYQRHSAQD-EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRN 1749 LED ++ + ++ E PVF DI V E + + + V +EW +N Sbjct: 309 LEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLD---VEVKAEHYELEWYKN 365 Query: 1750 GVPIEASNRLT-TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 V + R+ T + G AL ++ V +D G Y C A+N+ G + L V + Sbjct: 366 AVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEE- 424 Query: 1809 QLESQHESALQKIQQLEDSSRYQRRED 1835 + ES+ E+ + ++ R + ED Sbjct: 425 ESESEDETDEEFYEEKVVKLRKEHIED 451 Score = 44.4 bits (100), Expect = 0.002 Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 6/138 (4%) Query: 748 QQLEDYSKYQHQESIE-EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806 Q LED ++ + +E E E P F+ D+ E++EG N + + V +EW Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDI-EVKEGENVTLDVE---VKAEHYELEW 362 Query: 807 YKDGRPITASSRIT-SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865 YK+ + R+ + G +L I + +D G Y A+N G ++ VA Sbjct: 363 YKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEE 422 Query: 866 STVTADLGIPEQRRYIEK 883 + ++ Y EK Sbjct: 423 EEESESEDETDEEFYEEK 440 Score = 44.4 bits (100), Expect = 0.002 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH-DFSYVSL 2833 VF+ +I KEG+N+ + V+ ++EW+ N + G R + T + +L Sbjct: 331 VFVHEFTDIEVKEGENVTLDVEVKAEH---YELEWYKNAVDVVEGGRVRFTSGEGGKHAL 387 Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863 I ++D G Y C A N G T +G+L Sbjct: 388 VIEEVEDDDQGEYCCVAMNDAGRTTCAGNL 417 Score = 44.0 bits (99), Expect = 0.003 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 8/151 (5%) Query: 1289 QLLEDAARRTKQVREDITVM-QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWF 1347 Q LED A ++ E+ P F +IE EG NV L+ ++ + +EW+ Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKA---EHYELEWY 363 Query: 1348 CNGKPIKTGHRFR-PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406 N + G R R + E AL + V +D G Y C A N G + L V ++ Sbjct: 364 KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423 Query: 1407 DLILESQHPSGLEKIQYLEDTSRYKKTDIID 1437 + ES+ ++ Y E + +K I D Sbjct: 424 E---ESESEDETDEEFYEEKVVKLRKEHIED 451 Score = 43.6 bits (98), Expect = 0.004 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 2/91 (2%) Query: 68 EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127 E PP+F F + +G N + +++ + W + +VE + E G Sbjct: 326 EGDPPVFVHEFTDIEVKEGENVTLDVEVKAEHYEL-EWYKNAVDVVEGGRVRFTSGEG-G 383 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158 +L+I+++ D+GEY C A N G C+ Sbjct: 384 KHALVIEEVEDDDQGEYCCVAMNDAGRTTCA 414 Score = 42.7 bits (96), Expect = 0.007 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 6/114 (5%) Query: 2233 EVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292 E EP+ PP FV E V EG+ + +V+ H +E+Y N + R Sbjct: 321 EESEPEGDPPVFVHEFTDI-EVKEGENVTLDVEVKAEH---YELEWYKNAVDVVEGGRVR 376 Query: 2293 ITF-DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQ 2345 T + G +L I+ +D GEY A+N G T A ++TV A+ SES+ Sbjct: 377 FTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV-AEEEEESESE 429 Score = 41.9 bits (94), Expect = 0.012 Identities = 43/169 (25%), Positives = 69/169 (40%), Gaps = 12/169 (7%) Query: 904 ESTQKPEFKTPIK----DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT 959 E +PE P+ I +KEG + ++ +EW K+ V R+ Sbjct: 320 EEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKA---EHYELEWYKNAVDVVEGGRVR 376 Query: 960 -TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLE 1018 T G AL I+ V D G Y C A N G+ T + NLT+ +++ ES+ + Sbjct: 377 FTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEE---ESESEDETD 433 Query: 1019 KIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSA-HFEAR 1066 + Y E + K E+ ++ G K V ++A HF A+ Sbjct: 434 EEFYEEKVVKLRKEHIEDFYALEEEVGRGRFGVVRKCVHLKTAVHFVAK 482 Score = 41.1 bits (92), Expect = 0.021 Identities = 45/184 (24%), Positives = 72/184 (39%), Gaps = 10/184 (5%) Query: 1556 QVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWY 1614 Q LED ++ + + E P+ ++E+KEG+ + + V ++EWY Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLD---VEVKAEHYELEWY 363 Query: 1615 HNNKPLKSGSRFTETNNFGFV-ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673 N + G R T+ G AL I +D G Y C A+N G +G V ++ Sbjct: 364 KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423 Query: 1674 SIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIR--VAENQAAHFE 1731 ES+ E E K ++ +D + V +R V A HF Sbjct: 424 E---ESESEDETDEEFYEEKVVKLRKEHIEDFYALEEEVGRGRFGVVRKCVHLKTAVHFV 480 Query: 1732 ARLI 1735 A+ I Sbjct: 481 AKSI 484 Score = 41.1 bits (92), Expect = 0.021 Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 10/112 (8%) Query: 2348 EGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPT 2407 + LE I E E E + +P PVF +I+ ++EG+ D + V Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDP-----PVFVHEFTDIE-VKEGENVTLD---VEVKAEH 357 Query: 2408 LKVEWFRNEKLIEDSSRITKTH-DFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 ++EW++N + + R+ T + G ++ I V D+D+G Y C A N G Sbjct: 358 YELEWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAG 409 Score = 40.7 bits (91), Expect = 0.028 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK-TINDFG 3613 G+PP F +D+ + E + + + V +EW+ N ++ G RV+ T + G Sbjct: 327 GDPPVFVHEFTDIEVKEGENVTLD---VEVKAEHYELEWYKNAVDVVEGGRVRFTSGEGG 383 Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 L I V D G Y C A N G T + L V Sbjct: 384 KHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV 419 Score = 39.1 bits (87), Expect = 0.086 Identities = 34/116 (29%), Positives = 50/116 (43%), Gaps = 5/116 (4%) Query: 1956 QYLEDDSRYKRAVQDDSFVV-EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWY 2014 Q LED + + +++S + P F + EV EG V L+ V +EWY Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVE---VKAEHYELEWY 363 Query: 2015 CNGRPVQQGHRFK-TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 N V +G R + T+ + G AL I +D G Y C A N G ++ V Sbjct: 364 KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV 419 Score = 38.7 bits (86), Expect = 0.11 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 5/101 (4%) Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191 AE + E + +G P F +IE +K+G++ + V V ++EWY N Sbjct: 313 AEEEEEEEEESEPEGDPPVFVHEFTDIE-VKEGENVTLD---VEVKAEHYELEWYKNAVD 368 Query: 3192 MRHSTRIK-TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 + R++ T + G L I ++ D GEY C A N G Sbjct: 369 VVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAG 409 Score = 36.3 bits (80), Expect = 0.61 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR-PIHDFGYV 1502 P FV IE V EG++V + +++ + ++EW+KN V G R R + G Sbjct: 330 PVFVHEFTDIE-VKEGENVTLDVEVKA---EHYELEWYKNAVDVVEGGRVRFTSGEGGKH 385 Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 AL I ++ +D G Y C A+N G + LT Sbjct: 386 ALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLT 418 Score = 35.9 bits (79), Expect = 0.80 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 4/73 (5%) Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS-DFGFVTLDLVDVYERD 2980 ++ EG+ + L+ +V+ ++ ++EWY N + +G R + TS + G L + +V + D Sbjct: 340 EVKEGENVTLDVEVKAEH---YELEWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDD 396 Query: 2981 SGIYTCKAYNKRG 2993 G Y C A N G Sbjct: 397 QGEYCCVAMNDAG 409 >SB_9092| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 662 Score = 61.3 bits (142), Expect = 2e-08 Identities = 50/174 (28%), Positives = 73/174 (41%), Gaps = 7/174 (4%) Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695 +G AI + G P PTV W KG+ + P + S ++++LRIS P+DEG+Y Sbjct: 123 DGDAI-IKVDVDGFPKPTVVWKKGNGELIPIVNDRYS-VLEDFSLRISGMTPKDEGNYIF 180 Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755 +A K P + P P++ V G F +T KPT+QW+ Sbjct: 181 EVTQAALFRPFTIKAIAFSPPEIIQQP--VPIKRYVTV-GYNTSFTCIVTGFPKPTVQWI 237 Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809 G E F +E I N D G +TCR T +E A ++ Sbjct: 238 NPGG--REVDTFDPRYEIIGDTFYIYNIESNDKGNWTCRVTGGDVTIEAVATII 289 Score = 46.0 bits (104), Expect = 8e-04 Identities = 44/187 (23%), Positives = 74/187 (39%), Gaps = 19/187 (10%) Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595 + G P V LK G+ + P R K+ + +L + D G Y C A A ++ Sbjct: 319 RANGKPPPTVVILKAGR-IHP--RMKMRPGAASIEFYLLREH--DLGNYTCEAWGPARDS 373 Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655 + V A + KP +P EI V Q + +C + PL V Sbjct: 374 QGMPVVVNQSVALYTRDKPVINPGGSPKEIFS-----YVGNTQPVRINCDFISWPLANVT 428 Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK-VTQ 4714 ++G +++++ D+ TL + ED G Y C+ N G V ++ T Sbjct: 429 IWRG--------FYELTNGTDQATLYVWTYAWEDFGPYSCIGSNMFGEVNYTVWIRHATP 480 Query: 4715 PDQADNL 4721 P + +N+ Sbjct: 481 PSKPENI 487 Score = 42.7 bits (96), Expect = 0.007 Identities = 75/301 (24%), Positives = 115/301 (38%), Gaps = 44/301 (14%) Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLD------TKVTGTKPIDVYWLKNGKKVQPDIRNK 4561 RG F L ++ V + Q +R+D V G V W K ++ P + ++ Sbjct: 97 RGNTGNKIFLLWVTHIKVNTTQYLRIDGDAIIKVDVDGFPKPTVVWKKGNGELIPIVNDR 156 Query: 4562 --ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619 +LE+ ++L I P+D G Y + A R P A Sbjct: 157 YSVLED---FSLRISGMTPKDEGNY-IFEVTQAALFR---------------PFTIKAIA 197 Query: 4620 NAPPEIIE---PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTA 4675 +PPEII+ P+K + V G F+C + G P PTVQW G + + F Sbjct: 198 FSPPEIIQQPVPIK-RYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDT---FDPRYEI 253 Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE- 4734 T I D+G++ C + G VT+ A + A L A + +E Sbjct: 254 IGDTFYIYNIESNDKGNWTCRV--TGGDVTIEAVATIIDVYTAP-LVAEPSFPWVYWFEL 310 Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794 +PA + K PT+ L+ G + P +M A + E D G +TC Sbjct: 311 YRPASITCRANGKPPPTVVILKAGRIHP-----RMKMRPGAASIEFYLLREHDLGNYTCE 365 Query: 4795 A 4795 A Sbjct: 366 A 366 Score = 41.1 bits (92), Expect = 0.021 Identities = 47/167 (28%), Positives = 67/167 (40%), Gaps = 14/167 (8%) Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460 R VT G T F C VTG P P V W + D ++ + E I N+ +D Sbjct: 212 RYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRY---EIIGDTFYIYNIESNDK 268 Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE-RFSTLNVRE-GEPVVLNARAVGTP 518 G TC R G+ + +I + AP E F + E P + RA G P Sbjct: 269 GNWTC--RVTGGDVTIEAVATII--DVYTAPLVAEPSFPWVYWFELYRPASITCRANGKP 324 Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 P + K G I P ++R GA++++ + D Y C A Sbjct: 325 PPTVVILKAG-RIHPRMKMR----PGAASIEFYLLREHDLGNYTCEA 366 Score = 37.9 bits (84), Expect = 0.20 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 16/98 (16%) Query: 264 SPPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS--NKHEIITTHN 319 SPP+I Q+P K + G + F ++G P+P V W G R +++ ++EII Sbjct: 199 SPPEIIQQPVPIKRYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEII---- 254 Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 T + N + +D G++T C VT G + +E+ Sbjct: 255 GDTFYIYNIESNDKGNWT--------CRVTGGDVTIEA 284 Score = 35.9 bits (79), Expect = 0.80 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 4110 PPVFVSLPDAVT--VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN--GSRYKLTYDGMY 4165 PP + P + V G F C VTG PKP V W+ G V+ RY++ D Y Sbjct: 200 PPEIIQQPVPIKRYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEIIGDTFY 259 Query: 4166 HFDI 4169 ++I Sbjct: 260 IYNI 263 Score = 35.1 bits (77), Expect = 1.4 Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 14/129 (10%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVT 464 G R DC V+G E + ++ D +I + +G+ + L + N+T+ D G T Sbjct: 36 GASLRVDCTVSGGETFEGWFSPGGARVSDQEIERIHSDRNGDRYTLHVNNITVQDGGQYT 95 Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524 C R +G F + I+ +T +R ++ G P P + W Sbjct: 96 C--RGNTGNKIFLLWVTHIKVN-----------TTQYLRIDGDAIIKVDVDGFPKPTVVW 142 Query: 525 QKDGVPIIP 533 +K +IP Sbjct: 143 KKGNGELIP 151 >SB_3191| Best HMM Match : ig (HMM E-Value=3.5e-16) Length = 326 Score = 60.1 bits (139), Expect = 4e-08 Identities = 49/174 (28%), Positives = 73/174 (41%), Gaps = 7/174 (4%) Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695 +G AI + G P PTV W KG+ + P + + ++++LRIS P+DEG+Y Sbjct: 103 DGDAI-IKVDVDGFPKPTVVWKKGNGELIPIVNDRYT-VLEDFSLRISGMTPKDEGNYIF 160 Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755 +A K P + P P++ V G F +T KPT+QW+ Sbjct: 161 EVTQAALFRPFTIKAIAFSPPEIIQQP--VPIKRYVTL-GYNTSFTCIVTGFPKPTVQWI 217 Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809 G E F +E I N D G +TCR T +E A ++ Sbjct: 218 NPGG--REVDTFDPRYEIIGDTFYIYNIESNDKGNWTCRVTGGDVTIEAVATII 269 Score = 37.5 bits (83), Expect = 0.26 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 16/98 (16%) Query: 264 SPPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS--NKHEIITTHN 319 SPP+I Q+P K + G + F ++G P+P V W G R +++ ++EII Sbjct: 179 SPPEIIQQPVPIKRYVTLGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEII---- 234 Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 T + N + +D G++T C VT G + +E+ Sbjct: 235 GDTFYIYNIESNDKGNWT--------CRVTGGDVTIEA 264 Score = 37.1 bits (82), Expect = 0.35 Identities = 44/160 (27%), Positives = 66/160 (41%), Gaps = 31/160 (19%) Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLD------TKVTGTKPIDVYWLKNGKKVQPDIRNK 4561 RG F L ++ V + Q +R+D V G V W K ++ P + ++ Sbjct: 77 RGNTGNKIFLLWVTHIKVNTTQYLRIDGDAIIKVDVDGFPKPTVVWKKGNGELIPIVNDR 136 Query: 4562 --ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619 +LE+ ++L I P+D G Y + A R P A Sbjct: 137 YTVLED---FSLRISGMTPKDEGNY-IFEVTQAALFR---------------PFTIKAIA 177 Query: 4620 NAPPEIIE---PLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656 +PPEII+ P+K + V G F+C + G P PTVQW Sbjct: 178 FSPPEIIQQPVPIK-RYVTLGYNTSFTCIVTGFPKPTVQW 216 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 4110 PPVFVSLPDAVT--VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN--GSRYKLTYDGMY 4165 PP + P + V G F C VTG PKP V W+ G V+ RY++ D Y Sbjct: 180 PPEIIQQPVPIKRYVTLGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEIIGDTFY 239 Query: 4166 HFDI 4169 ++I Sbjct: 240 IYNI 243 Score = 34.3 bits (75), Expect = 2.5 Identities = 30/129 (23%), Positives = 51/129 (39%), Gaps = 14/129 (10%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVT 464 G R DC V+G E + ++ D +I + +G+ + L + N+T D G T Sbjct: 16 GASLRVDCTVSGGETFEGWFSPGGARVSDQEIERIHSDRNGDRYTLHVNNITAQDGGQYT 75 Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524 C R +G F + I+ +T +R ++ G P P + W Sbjct: 76 C--RGNTGNKIFLLWVTHIKVN-----------TTQYLRIDGDAIIKVDVDGFPKPTVVW 122 Query: 525 QKDGVPIIP 533 +K +IP Sbjct: 123 KKGNGELIP 131 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 5/84 (5%) Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460 R VT G T F C VTG P P V W + D ++ + E I N+ +D Sbjct: 192 RYVTLGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRY---EIIGDTFYIYNIESNDK 248 Query: 461 GVVTCVARNKSGETAFQCRLNVIE 484 G TC R G+ + +I+ Sbjct: 249 GNWTC--RVTGGDVTIEAVATIID 270 >SB_41624| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 917 Score = 60.1 bits (139), Expect = 4e-08 Identities = 59/209 (28%), Positives = 88/209 (42%), Gaps = 25/209 (11%) Query: 4553 KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612 +VQ I I+E L I +A D+G Y C A +A VV + KD Sbjct: 538 RVQQSIDGNIIET----VLKIRDATTSDAGNYTCTLEGPGPSALDNATAVVDV---KDLS 590 Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672 P A + P ++ V E + E +C + P PTV W K + P +Y +S Sbjct: 591 HPLI-AMSTPTKLT-------VNETSSFELTCVVTASPGPTVTWTKSAE--DPKRY-SVS 639 Query: 4673 RTADEYTLRI-SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRD 4729 + YTLR+ S +P+D G + C A N+ G T + + V + L P + D Sbjct: 640 HSNGRYTLRVTSSVYPDDAGKFICRAENAEGFSTKSVIVNVHECLSLSRLAKPIIEKKED 699 Query: 4730 IVVYEGQPAQFKTQI----TSKIKPTIQW 4754 V +P++F +S P IQW Sbjct: 700 TRVIVAKPSEFVRMACPIKSSNPPPMIQW 728 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/125 (24%), Positives = 49/125 (39%), Gaps = 4/125 (3%) Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736 E L+I +A D G+Y C A V D + L A++ + V E Sbjct: 549 ETVLKIRDATTSDAGNYTCTLEGPGPSALDNATAVVDVKDLSHPLIAMSTPTKLTVNETS 608 Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRA 4795 + +T+ PT+ W + + + + H G + + + Y +D G F CRA Sbjct: 609 SFELTCVVTASPGPTVTWTKSA---EDPKRYSVSHSNGRYTLRVTSSVYPDDAGKFICRA 665 Query: 4796 TTAAG 4800 A G Sbjct: 666 ENAEG 670 Score = 42.3 bits (95), Expect = 0.009 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 5/98 (5%) Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026 VD K + + + T L ET+ FE P V W K R++ + Sbjct: 584 VDVKDLSHPLIAMSTPTKLTVNETSSFELTCVVTASPGPTVTWT---KSAEDPKRYSVSH 640 Query: 4027 DFG-YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063 G Y VYP+D+G+++CRA N G TK+VI Sbjct: 641 SNGRYTLRVTSSVYPDDAGKFICRAENAEGF-STKSVI 677 Score = 41.9 bits (94), Expect = 0.012 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 4/96 (4%) Query: 1850 LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILT- 1908 ++ PTKL+ +++ +E P V W K + RY S+ G L + + Sbjct: 596 MSTPTKLTVNETSSFELTCVVTASPGPTVTWT---KSAEDPKRYSVSHSNGRYTLRVTSS 652 Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944 VY +D+G++ C+A N G + S+ +NV S+ R Sbjct: 653 VYPDDAGKFICRAENAEGFSTKSVIVNVHECLSLSR 688 Score = 37.9 bits (84), Expect = 0.20 Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 7/136 (5%) Query: 3424 VPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI- 3482 + +S L E + FE T P V W KS + R+ G L + Sbjct: 594 IAMSTPTKLTVNETSSFELTCVVTASPGPTVTWT---KSAEDPKRYSVSHSNGRYTLRVT 650 Query: 3483 SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYS 3542 S YP+D+G+++CRA N E +T S+ V + L +E D + S Sbjct: 651 SSVYPDDAGKFICRAEN--AEGFSTKSVIVNVHECLSLSRLAKPIIEKKEDTRVIVAKPS 708 Query: 3543 GTVDTLTPEAESGNPP 3558 V P +S NPP Sbjct: 709 EFVRMACP-IKSSNPP 723 Score = 37.5 bits (83), Expect = 0.26 Identities = 38/153 (24%), Positives = 55/153 (35%), Gaps = 9/153 (5%) Query: 424 TWFINDR--QIRDDYNHKILVNESGN---HALMITNVTLSDSGVVTCVARNKSGETAFQC 478 TW D R N ++ + GN L I + T SD+G TC G +A Sbjct: 521 TWTQTDHTGHTRTVSNDRVQQSIDGNIIETVLKIRDATTSDAGNYTCTLEGP-GPSALDN 579 Query: 479 RLNVIEKEQVVAPKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537 V++ + + P T L V E L +P P +TW K P Sbjct: 580 ATAVVDVKDLSHPLIAMSTPTKLTVNETSSFELTCVVTASPGPTVTWTKSAED--PKRYS 637 Query: 538 RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 H++G + DA + C A+N G Sbjct: 638 VSHSNGRYTLRVTSSVYPDDAGKFICRAENAEG 670 Score = 36.7 bits (81), Expect = 0.46 Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 7/137 (5%) Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166 VL+I T+D+G Y+C G + + VD P + L ++ Sbjct: 551 VLKIRDATTSDAGNYTCTLEGP-GPSALDNATAVVDVKDLSHPLIA--MSTPTKLTVNET 607 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQ-PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 + FE T V P + W + + P R+S + S+ + + + D+G+++CR Sbjct: 608 SSFELTCVVTASPGPTVTWTKSAEDPKRYSV---SHSNGRYTLRVTSSVYPDDAGKFICR 664 Query: 3226 AYNKYGEDFTRATINCY 3242 A N G +N + Sbjct: 665 AENAEGFSTKSVIVNVH 681 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 6/87 (6%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 + +S + E + C V S PT + W K RY +H +L Sbjct: 594 IAMSTPTKLTVNETSSFELTCVVTASPGPT--VTW---TKSAEDPKRYSVSHSNGRYTLR 648 Query: 2835 ITHT-YEEDSGIYTCKATNSKGSATTS 2860 +T + Y +D+G + C+A N++G +T S Sbjct: 649 VTSSVYPDDAGKFICRAENAEGFSTKS 675 Score = 35.5 bits (78), Expect = 1.1 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 4/89 (4%) Query: 1721 RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM-KYVNPED 1779 ++ N+ + FE + P V W ++ E R + H G L + V P+D Sbjct: 601 KLTVNETSSFELTCVVTASPGPTVTWTKSA---EDPKRYSVSHSNGRYTLRVTSSVYPDD 657 Query: 1780 SGTYTCRAINELGEAVTSSTLFVQSKASL 1808 +G + CRA N G + S + V SL Sbjct: 658 AGKFICRAENAEGFSTKSVIVNVHECLSL 686 Score = 35.1 bits (77), Expect = 1.4 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 5/110 (4%) Query: 1567 TDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF 1626 T +VD P+ S ++ + + FE + + V W K + R+ Sbjct: 581 TAVVDVKDLSHPLIAMSTPT-KLTVNETSSFELTCVVTASPGPTVTW---TKSAEDPKRY 636 Query: 1627 TETNNFGFVALDIMSCL-PEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675 + +++ G L + S + P+D+G + CRA NA G + S I VH S+ Sbjct: 637 SVSHSNGRYTLRVTSSVYPDDAGKFICRAENAEGFSTKSVIVNVHECLSL 686 Score = 34.7 bits (76), Expect = 1.9 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 4/68 (5%) Query: 2392 QTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG-YVSMTISHVRDEDEGVYM 2450 +T+ F+ + P V W K ED R + +H G Y S V +D G ++ Sbjct: 606 ETSSFELTCVVTASPGPTVTW---TKSAEDPKRYSVSHSNGRYTLRVTSSVYPDDAGKFI 662 Query: 2451 CRASNLLG 2458 CRA N G Sbjct: 663 CRAENAEG 670 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 5/85 (5%) Query: 263 VSPPKIAQK-PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321 +S P IA P + E + + ++ +P P VTW K+ + + ++ + ++ Sbjct: 589 LSHPLIAMSTPTKLTVNETSSFELTCVVTASPGPTVTWTKSAE---DPKRYSVSHSNGRY 645 Query: 322 TLRVRNT-QKSDSGHYTLLAENPNG 345 TLRV ++ D+G + AEN G Sbjct: 646 TLRVTSSVYPDDAGKFICRAENAEG 670 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDI-NS 2572 ++ P++L + + +E V P W + + K R+ +H G TL + +S Sbjct: 596 MSTPTKLTVNETSSFELTCVVTASPGPTVTWTKSAEDPK---RYSVSHSNGRYTLRVTSS 652 Query: 2573 VVANDAGLYMCKAINRAG 2590 V +DAG ++C+A N G Sbjct: 653 VYPDDAGKFICRAENAEG 670 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/91 (23%), Positives = 41/91 (45%), Gaps = 4/91 (4%) Query: 2112 LTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDI 2171 L A+++ L + + FE P T+ W + + + RY +H G L + Sbjct: 593 LIAMSTPTKLTVNETSSFELTCVVTASPGPTVTWTKSAEDPK---RYSVSHSNGRYTLRV 649 Query: 2172 LYT-YAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + Y +D+G ++C+A N G + + + V Sbjct: 650 TSSVYPDDAGKFICRAENAEGFSTKSVIVNV 680 Score = 32.7 bits (71), Expect = 7.5 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT-NVTLSDSG 461 V E C VT P P VTW + +D + + +G + L +T +V D+G Sbjct: 604 VNETSSFELTCVVTASPGPTVTW----TKSAEDPKRYSVSHSNGRYTLRVTSSVYPDDAG 659 Query: 462 VVTCVARNKSGETAFQCRLNVIE 484 C A N G + +NV E Sbjct: 660 KFICRAENAEGFSTKSVIVNVHE 682 Score = 32.3 bits (70), Expect = 9.9 Identities = 25/104 (24%), Positives = 45/104 (43%), Gaps = 6/104 (5%) Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYA-YAED 2046 ++T E T P V W + + R+ ++ G L + + Y +D Sbjct: 601 KLTVNETSSFELTCVVTASPGPTVTWT---KSAEDPKRYSVSHSNGRYTLRVTSSVYPDD 657 Query: 2047 TGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQE 2090 G ++C+A NA E +T SV V+ L L L + ++K ++ Sbjct: 658 AGKFICRAENA--EGFSTKSVIVNVHECLSLSRLAKPIIEKKED 699 >SB_13651| Best HMM Match : I-set (HMM E-Value=4e-17) Length = 333 Score = 59.7 bits (138), Expect = 6e-08 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%) Query: 390 LAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448 +AP F + DV E C +GRP P VTW +N + + + +G+ Sbjct: 157 VAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPNVTW-VNKT------SGSPVAHGTGSA 209 Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508 L + + +G+ C A N G A + +I V P + VR GE + Sbjct: 210 TLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTII----VQYPPEITPIQNTTVRAGETI 265 Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN- 567 L G PTP ++W K G H+ GG KA Y CTA N Sbjct: 266 TLTCAVAGNPTPSVSWSKAGSG---------HSTGGNVFTKAGATKAV-TGQYVCTAVNT 315 Query: 568 VAGSTATR 575 V G+T TR Sbjct: 316 VTGNTQTR 323 Score = 46.0 bits (104), Expect = 8e-04 Identities = 40/148 (27%), Positives = 63/148 (42%), Gaps = 22/148 (14%) Query: 4512 VPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570 V P+FT + + +++V V +G +V W+ N P + G+ T Sbjct: 157 VAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPNVTWV-NKTSGSP-----VAHGTGSAT 210 Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 L +L+ +G Y+C AIN G T+D T PPEI P++ Sbjct: 211 LSLLKIQRHQAGLYQCQAINDVGRGAI----------TQDV----TIIVQYPPEIT-PIQ 255 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 + V G+ I +C + G P P+V W K Sbjct: 256 NTTVRAGETITLTCAVAGNPTPSVSWSK 283 Score = 42.3 bits (95), Expect = 0.009 Identities = 26/126 (20%), Positives = 49/126 (38%), Gaps = 10/126 (7%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 VAE + +C G+P P V W + + ++ TL + + G Y Sbjct: 171 VAENDDVTNTCSASGRPAPNVTW------VNKTSGSPVAHGTGSATLSLLKIQRHQAGLY 224 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753 +C A N GR + + + P +TP+++ V G+ + P++ Sbjct: 225 QCQAINDVGRGAITQDVTII----VQYPPEITPIQNTTVRAGETITLTCAVAGNPTPSVS 280 Query: 4754 WLREGA 4759 W + G+ Sbjct: 281 WSKAGS 286 Score = 40.3 bits (90), Expect = 0.037 Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 8/105 (7%) Query: 2630 PEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA 2689 P D V+ AP FT+ L S + E V R PN + W V T+G+ Sbjct: 147 PSASWDLNVKVAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPN--VTW----VNKTSGS 200 Query: 2690 RLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 + G TLS+ ++ +G+Y C+A N +G T + I Sbjct: 201 PV--AHGTGSATLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTI 243 Score = 35.9 bits (79), Expect = 0.80 Identities = 39/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%) Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDV 1836 P D+ T + G+ + S + AS+ E + L KI+ SS Sbjct: 96 PNDTDTIYKGRVYFYGDFTSCSGVVEIRNASVVHEKPY---LVKIRT-SSSSPLSPSASW 151 Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896 ++ V AP F + L+ ++E C P PN V W K S + T Sbjct: 152 DLNVKVAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPN--VTWV--NKTSGSPVAHGT- 206 Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927 G A L +L + +G Y C+AIN++G+ Sbjct: 207 ---GSATLSLLKIQRHQAGLYQCQAINDVGR 234 Score = 35.9 bits (79), Expect = 0.80 Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 15/134 (11%) Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEAT 2000 S+++ +H++ L + Q + D R QD + +V+ P PI+N V G + L T Sbjct: 212 SLLKIQRHQAGLYQCQAINDVGR-GAITQDVTIIVQYPPEITPIQNTTVRAGETITL--T 268 Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV-G 2059 +PT V W G GH G A TG Y+C A N V G Sbjct: 269 CAVAGNPTPSVSWSKAG----SGH------STGGNVFTKAGATKAVTGQYVCTAVNTVTG 318 Query: 2060 EAVT-TSSVKVDAK 2072 T T+S V K Sbjct: 319 NTQTRTASTYVMVK 332 Score = 33.5 bits (73), Expect = 4.3 Identities = 45/195 (23%), Positives = 71/195 (36%), Gaps = 25/195 (12%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P FT+ +D++E S +G + + W +H G Sbjct: 159 PAFTSSLSSSLDVAENDDVTNTCSA--SGRPAPNVTWVNKTSGSPVAH------GTGSAT 210 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L +L + +G Y C+A N G+ I+ + + Q P T IQN ++ G++ Sbjct: 211 LSLLKIQRHQAGLYQCQAINDVGRGAITQDVTII----VQYPPEITPIQNTT-VRAGETI 265 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 C V +P + W G HST G V A +G+YVC A Sbjct: 266 TLTCAV--AGNPTPSVSWSKAGS--GHST--------GGNVFTKAGATKAVTGQYVCTAV 313 Query: 3228 NKYGEDFTRATINCY 3242 N + T + Y Sbjct: 314 NTVTGNTQTRTASTY 328 Score = 32.3 bits (70), Expect = 9.9 Identities = 33/133 (24%), Positives = 53/133 (39%), Gaps = 12/133 (9%) Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHT-VEESEGVRFECRVEPKEDPKLRIEW 3865 KI+ +S + + V P F + + S V E++ V C + P + W Sbjct: 136 KIRTSSSSPLSPSASWDLNVKVAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPN--VTW 193 Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED-FTK-ATISCKK 3923 P H G +L +L + +G Y C+A+ND G T+ TI + Sbjct: 194 VNKTSGSPVAH------GTGSATLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTIIVQY 247 Query: 3924 LPDII-LQNQVPR 3935 P+I +QN R Sbjct: 248 PPEITPIQNTTVR 260 Score = 32.3 bits (70), Expect = 9.9 Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 13/105 (12%) Query: 1304 DITVMQAPQFSRALHN-IETVEGTNVHLECRLQPVGDQTMRVEWF--CNGKPIKTGHRFR 1360 D+ V AP F+ +L + ++ E +V C G V W +G P+ Sbjct: 152 DLNVKVAPAFTSSLSSSLDVAENDDVTNTCSAS--GRPAPNVTWVNKTSGSPV------- 202 Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405 A+ L LL + +G+Y CQA N +G + + +I + Sbjct: 203 -AHGTGSATLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTIIVQ 246 Score = 32.3 bits (70), Expect = 9.9 Identities = 12/40 (30%), Positives = 23/40 (57%) Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 G L++ + H AG Y C+A N +G+ + ++TI+ + Sbjct: 207 GSATLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTIIVQ 246 >SB_59628| Best HMM Match : I-set (HMM E-Value=5e-21) Length = 209 Score = 59.7 bits (138), Expect = 6e-08 Identities = 55/200 (27%), Positives = 80/200 (40%), Gaps = 20/200 (10%) Query: 4511 IVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569 IV +FT+T NV+ G + L G V W K G +Q R + Sbjct: 10 IVNATFTVTIGANVSALRGSSITLTCTAEGLPVPAVVWKKGGATLQQGGR--------AF 61 Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD-KPKPQTKAANAPPEIIEP 4628 TL E+ DSG+Y+CVA N G A + + K PK + N + Sbjct: 62 TLSSTES--ADSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKR 119 Query: 4629 LKDKIVA------EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682 L I+ EG+ +E C +G P P V W+ + S ++ L I Sbjct: 120 LFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSI 177 Query: 4683 SEAFPEDEGDYKCVAYNSAG 4702 E E++G Y C + N+AG Sbjct: 178 IEITAEEQGQYMCKSKNTAG 197 Score = 55.6 bits (128), Expect = 9e-07 Identities = 53/217 (24%), Positives = 85/217 (39%), Gaps = 32/217 (14%) Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALD 3756 FTV I N+ G + C E G P + W G G R TL+ Sbjct: 15 FTVTIGANVSALRGSSITLTCTAE--GLPVPAVVWKKGGATLQQGGRAFTLSS------- 65 Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRI 3816 + D+G Y C ATN G+A ++ +T +KI++ +I Sbjct: 66 ---TESADSGRYDCVATNLKGTAMASSAVTIH-----------------DKIEKRVAPKI 105 Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876 + K+ I S + I + EG E + PK + W+ NG + Sbjct: 106 LSS-KKNLIASENKRLFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESD 164 Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913 + + G +L I+ + AE+ G+Y+C++ N GED Sbjct: 165 TLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGED 199 Score = 54.4 bits (125), Expect = 2e-06 Identities = 59/224 (26%), Positives = 83/224 (37%), Gaps = 31/224 (13%) Query: 1846 FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALD 1905 F + G S C E P P V W G LQ G R A Sbjct: 15 FTVTIGANVSALRGSSITLTCTAEGLPVP--AVVWKKGGATLQQGGR----------AFT 62 Query: 1906 ILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYK 1965 + + DSG Y C A N G A++S + + K +EK + S K Sbjct: 63 LSSTESADSGRYDCVATNLKGTAMASSAVTIHDK------------IEKRVAPKILSSKK 110 Query: 1966 RAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR 2025 + ++ + G N + EG + L+ + P V W+ NG V + Sbjct: 111 NLIASENKRLFYHIIGG---NITILEGKDLELQCP--SIGTPKPAVTWFINGSAVTESDT 165 Query: 2026 FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 K + G AL I+ AE+ G YMCK+ N GE + TS V Sbjct: 166 LKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETSYTTV 207 Score = 54.0 bits (124), Expect = 3e-06 Identities = 56/211 (26%), Positives = 83/211 (39%), Gaps = 30/211 (14%) Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045 N G + L T T P V W G +QQG R A + + Sbjct: 22 NVSALRGSSITL--TCTAEGLPVPAVVWKKGGATLQQGGR----------AFTLSSTESA 69 Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQP 2105 D+G Y C ATN G A+ +S+V + D ++++ KI +K I E Sbjct: 70 DSGRYDCVATNLKGTAMASSAVTIH-------DKIEKRVAPKILSSKK----NLIASEN- 117 Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 + +F + + EG +C I P + WF NG + + + G Sbjct: 118 --KRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLKVDPNTG 173 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNT 2196 AL I+ AE+ G YMCK+ N GE + T Sbjct: 174 --ALSIIEITAEEQGQYMCKSKNTAGEDLET 202 Score = 54.0 bits (124), Expect = 3e-06 Identities = 46/169 (27%), Positives = 75/169 (44%), Gaps = 20/169 (11%) Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161 A ++S + DSG Y VA N G A S+++T+ + I+ + L K I Sbjct: 60 AFTLSSTESADSGRYDCVATNLKGTAMASSAVTIHDK--IEKRVAPKILSSKKNLIA--- 114 Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221 S++K +F + + EGK++ L+C +G P V WF NG +VT Sbjct: 115 -----------SENKRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVT 161 Query: 1222 VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270 K + G AL II T+ + G+Y ++ N G ++ V+ Sbjct: 162 ESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETSYTTVV 208 Score = 53.6 bits (123), Expect = 4e-06 Identities = 48/200 (24%), Positives = 74/200 (37%), Gaps = 23/200 (11%) Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N G+ G P P V W K G L + + +T+ +DS Sbjct: 22 NVSALRGSSITLTCTAEGLPVPAVVWKKGGATLQQGGR----------AFTLSSTESADS 71 Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393 G Y +A N G + S + + E V + I +++ I K L Sbjct: 72 GRYDCVATNLKGTAMASSAVTIHDKIEKRVAPK----ILSSKKN----LIASENKRLFYH 123 Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453 + + + EGK C G P P VTWFIN + + K+ + AL I Sbjct: 124 IIG--GNITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV---DPNTGALSII 178 Query: 454 NVTLSDSGVVTCVARNKSGE 473 +T + G C ++N +GE Sbjct: 179 EITAEEQGQYMCKSKNTAGE 198 Score = 53.6 bits (123), Expect = 4e-06 Identities = 45/183 (24%), Positives = 71/183 (38%), Gaps = 31/183 (16%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 G C G P P V W + + G A +++ +DSG C Sbjct: 28 GSSITLTCTAEGLPVPAVVWKKGGATL-----------QQGGRAFTLSSTESADSGRYDC 76 Query: 466 VARNKSGETAFQCRLNVIEK-EQVVAPKFVERFSTL-----------------NVREGEP 507 VA N G + + +K E+ VAPK + L + EG+ Sbjct: 77 VATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYHIIGGNITILEGKD 136 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 + L ++GTP P +TW +G + + L++ + GA L I A + Y C ++N Sbjct: 137 LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTGA--LSIIEITAEEQGQYMCKSKN 194 Query: 568 VAG 570 AG Sbjct: 195 TAG 197 Score = 50.8 bits (116), Expect = 3e-05 Identities = 55/210 (26%), Positives = 87/210 (41%), Gaps = 32/210 (15%) Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378 N+ + G+++ L C + G V W G ++ G R A L S Sbjct: 22 NVSALRGSSITLTCTAE--GLPVPAVVWKKGGATLQQGGR----------AFTLSSTESA 69 Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDE 1438 DSG Y C ATN G A+ S A+ + K + + + S + + E+ + II Sbjct: 70 DSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYH--IIGG 127 Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498 ++TI +EG+ + +C + V WF NG VT + + Sbjct: 128 NITI--------------LEGKDLELQCP--SIGTPKPAVTWFINGSAVTESDTLKVDPN 171 Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528 G AL II++ AE+ G Y C++ N G D Sbjct: 172 TG--ALSIIEITAEEQGQYMCKSKNTAGED 199 Score = 48.8 bits (111), Expect = 1e-04 Identities = 53/193 (27%), Positives = 81/193 (41%), Gaps = 31/193 (16%) Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 G +I +C G P+P V W KG ++ Q R +TL +E+ D G Y CV Sbjct: 28 GSSITLTCTAEGLPVPAVVWKKGGATLQ-----QGGRA---FTLSSTES--ADSGRYDCV 77 Query: 4697 AYNSAGR------VTVAAKL-KVTQP---DQADNLPALTPLR--------DIVVYEGQPA 4738 A N G VT+ K+ K P NL A R +I + EG+ Sbjct: 78 ATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYHIIGGNITILEGKDL 137 Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798 + + KP + W G+ + E+ ++ + N L I E+ G + C++ Sbjct: 138 ELQCPSIGTPKPAVTWFINGSAVTESDTLKV--DPNTGALSIIEITAEEQGQYMCKSKNT 195 Query: 4799 AGQ-VETSAKLVV 4810 AG+ +ETS VV Sbjct: 196 AGEDLETSYTTVV 208 Score = 46.8 bits (106), Expect = 4e-04 Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 31/213 (14%) Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703 FT + + + G + L E P + W K G TL G R + Sbjct: 15 FTVTIGANVSALRGSSITLTCTAEGLPVP--AVVWKKGGATLQQGGR----------AFT 62 Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXX 2763 ++S + DSG Y C ATNL G A++++++ I D+ + + + P L L Sbjct: 63 LSSTESADSGRYDCVATNLKGTAMASSAVTIHDK---IEKRVAPKILSSKKNLIASENKR 119 Query: 2764 XXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPS-RDPTLKIEWFFNNKPLPSGTRY 2822 NI EG ++ +C PS P + WF N + Sbjct: 120 LFYHIIG----------GNITILEGKDLELQC---PSIGTPKPAVTWFINGSAVTESDTL 166 Query: 2823 KSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855 K D + +L I E+ G Y CK+ N+ G Sbjct: 167 KV--DPNTGALSIIEITAEEQGQYMCKSKNTAG 197 Score = 44.4 bits (100), Expect = 0.002 Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 23/206 (11%) Query: 931 ARLEPIGDSTLRVEWLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988 A + + S++ + +G PV A + G A T+ S D+G Y C A N Sbjct: 21 ANVSALRGSSITLTCTAEGLPVPAVVWKKGGATLQQGGRAFTLSSTESADSGRYDCVATN 80 Query: 989 AIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGP 1048 G A S+ +TI K +EK A + + + K F Sbjct: 81 LKGTAMASSAVTIHDK------------IEK----RVAPKILSSKKNLIASENKRLFYHI 124 Query: 1049 LKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASV 1108 + G I+EG+ E + V W+ NG +T ++ ++ + G AL I + Sbjct: 125 IGGNITILEGKD--LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEI 180 Query: 1109 RAEDSGVYTVVARNAAGEAQLSASMT 1134 AE+ G Y ++N AGE L S T Sbjct: 181 TAEEQGQYMCKSKNTAGE-DLETSYT 205 Score = 42.7 bits (96), Expect = 0.007 Identities = 42/157 (26%), Positives = 62/157 (39%), Gaps = 20/157 (12%) Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494 + T+S D G Y C A+NL G T H KI+K P Sbjct: 60 AFTLSSTESADSGRYDCVATNLKGTAMASSAV-----------TIHD----KIEKRVAPK 104 Query: 2495 ERRSEEPDREFE-KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553 S++ E K +F ++ G + EG+ E + +G P W+ING + Sbjct: 105 ILSSKKNLIASENKRLFYHIIGGNITILEGKDL--ELQCPSIGTPKPAVTWFINGSAVTE 162 Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 + + G L I + A + G YMCK+ N AG Sbjct: 163 SDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAG 197 Score = 42.7 bits (96), Expect = 0.007 Identities = 35/138 (25%), Positives = 57/138 (41%), Gaps = 21/138 (15%) Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDK-SKGQKPRFTTHIQNIEG----------- 3160 T++ DSG Y C ATN G A S + DK K P+ + +N+ Sbjct: 66 TESADSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYHII 125 Query: 3161 -----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQ 3215 + +G+ +C + P + W+ NG + S +K + G L I Sbjct: 126 GGNITILEGKDLELQCPSIGTPKP--AVTWFINGSAVTESDTLKVDPNTG--ALSIIEIT 181 Query: 3216 NHDSGEYVCRAYNKYGED 3233 + G+Y+C++ N GED Sbjct: 182 AEEQGQYMCKSKNTAGED 199 Score = 41.9 bits (94), Expect = 0.012 Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 19/163 (11%) Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTS 1695 A + S DSG Y C A N G A+ S +H K +E + P++ +S Sbjct: 60 AFTLSSTESADSGRYDCVATNLKGTAMASSAVTIHDK----IEKR---VAPKIL----SS 108 Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755 K +++++ + + + +I + E + E + +G PK V W NG + Sbjct: 109 KKNLIASENKRL----FYHIIGGNITILEGK--DLELQCPSIGTPKPAVTWFINGSAVTE 162 Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798 S+ L + G AL++ + E+ G Y C++ N GE + +S Sbjct: 163 SDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETS 203 Score = 41.9 bits (94), Expect = 0.012 Identities = 38/165 (23%), Positives = 68/165 (41%), Gaps = 24/165 (14%) Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894 ++ T DSG Y C ATN KG+A S ++ T H + +E+ + Sbjct: 63 LSSTESADSGRYDCVATNLKGTAMASSAV-----------TIH-------DKIEKRVAPK 104 Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954 + ++ + K + I ++EG+ L L Q P + W+ NG + Sbjct: 105 ILSSKKNLIASEN--KRLFYHIIGGNITILEGKDLEL--QCPSIGTPKPAVTWFINGSAV 160 Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999 + K+ + G L ++++ + G Y CK+ N GE +S Sbjct: 161 TESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETS 203 Score = 41.5 bits (93), Expect = 0.016 Identities = 48/212 (22%), Positives = 85/212 (40%), Gaps = 31/212 (14%) Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251 G +I L C E G P V W G ++ G R A + SAD+G Y Sbjct: 28 GSSITLTCTAE--GLPVPAVVWKKGGATLQQGGR----------AFTLSSTESADSGRYD 75 Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP 1311 A N G+A S+ V + ++ + ++ +I + ++ R ++ Sbjct: 76 CVATNLKGTAMASSAVTIHDKIE-------KRVAPKILSSKKNLIASENKRLFYHIIGG- 127 Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371 NI +EG ++ L+C +G V WF NG + + + + AL Sbjct: 128 -------NITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLK--VDPNTGALS 176 Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 ++ + E+ G Y C++ N GE + + V+ Sbjct: 177 IIEITAEEQGQYMCKSKNTAGEDLETSYTTVV 208 Score = 40.7 bits (91), Expect = 0.028 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N + EG D + Q G P+P VTWF NG + S+ ++ N L + + Sbjct: 128 NITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV--DPNTGALSIIEITAEEQ 185 Query: 334 GHYTLLAENPNGCIVTSGYLAV 355 G Y ++N G + + Y V Sbjct: 186 GQYMCKSKNTAGEDLETSYTTV 207 Score = 39.9 bits (89), Expect = 0.049 Identities = 50/214 (23%), Positives = 84/214 (39%), Gaps = 32/214 (14%) Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704 +V+A+ G I E G P + W K G +++ R + + S Sbjct: 22 NVSALRGSSITLTCTAE--GLPVPAVVWKKGGATLQQGGR----------AFTLSSTESA 69 Query: 705 DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEE 764 DSG Y C A + G A + VT IE+ P+ L + L Sbjct: 70 DSGRYDCVATNLKGTAMASSA--VTIHDKIEKRVA-PKILSSKKNLI------------- 113 Query: 765 QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824 + + F + + EG++ E Q + P V W+ +G +T S + N Sbjct: 114 ASENKRLFYHIIGGNITILEGKD--LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPN 171 Query: 825 FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858 G +L+I+ + AE+ G Y ++ N GE + T+ Sbjct: 172 TG--ALSIIEITAEEQGQYMCKSKNTAGEDLETS 203 Score = 39.5 bits (88), Expect = 0.065 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 4/72 (5%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 I EG+ C I G P V WF N + +S + + G +++I + E++G Sbjct: 131 ILEGKDLELQCPSI--GTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEITAEEQG 186 Query: 2448 VYMCRASNLLGE 2459 YMC++ N GE Sbjct: 187 QYMCKSKNTAGE 198 Score = 39.1 bits (87), Expect = 0.086 Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 15/131 (11%) Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEK-RRQGRGGIVPPSFTLTAQ------------NV 4523 DS + VA N GTA S+ + + +K ++ I+ L A N+ Sbjct: 70 DSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYHIIGGNI 129 Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583 + G+ + L GT V W NG V K+ + T L I+E ++ G+ Sbjct: 130 TILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV--DPNTGALSIIEITAEEQGQ 187 Query: 4584 YECVAINSAGE 4594 Y C + N+AGE Sbjct: 188 YMCKSKNTAGE 198 Score = 38.3 bits (85), Expect = 0.15 Identities = 41/161 (25%), Positives = 63/161 (39%), Gaps = 24/161 (14%) Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEI 3685 D+G Y C ATN G A S + + + + P++ S K+ I Sbjct: 70 DSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSS----------------KKNLI 113 Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745 E+++ F I NI + EG + C +G P + WF NG + Sbjct: 114 ASENKR----LFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLK 167 Query: 3746 TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786 + G AL I I A + G+Y C++ N G T+ T Sbjct: 168 VDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETSYTT 206 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713 ++EG+ LE Q P + WF NG +T LK + G LSI + ++ G Sbjct: 131 ILEGKD--LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEITAEEQG 186 Query: 2714 IYTCKATNLLGEAVSTA 2730 Y CK+ N GE + T+ Sbjct: 187 QYMCKSKNTAGEDLETS 203 Score = 37.9 bits (84), Expect = 0.20 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 4/98 (4%) Query: 905 STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964 S K F I I+I EG E + IG V W +G V S + N Sbjct: 115 SENKRLFYHIIGGNITILEG--KDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNT 172 Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 G AL+I +T + G Y C++ N G+ ++ T+V Sbjct: 173 G--ALSIIEITAEEQGQYMCKSKNTAGEDLETSYTTVV 208 Score = 37.5 bits (83), Expect = 0.26 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 2/70 (2%) Query: 3988 METTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYL 4047 +E E Q +G P V WF NG + + T D A++ + E+ G+Y+ Sbjct: 132 LEGKDLELQCPSIGTPKPAVTWFINGSAVTESD--TLKVDPNTGALSIIEITAEEQGQYM 189 Query: 4048 CRATNLYGMD 4057 C++ N G D Sbjct: 190 CKSKNTAGED 199 Score = 33.9 bits (74), Expect = 3.2 Identities = 13/40 (32%), Positives = 20/40 (50%) Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 +T+ EG+ C G PKP V W +NG+ + K+ Sbjct: 129 ITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV 168 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV-ILEISPTYPEDSGEYL 3494 E E + P V W+ NG ++ + + G + I+EI+ E+ G+Y+ Sbjct: 133 EGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTGALSIIEITA---EEQGQYM 189 Query: 3495 CRAYNNYGEAVTTA 3508 C++ N GE + T+ Sbjct: 190 CKSKNTAGEDLETS 203 Score = 32.7 bits (71), Expect = 7.5 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 10/74 (13%) Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557 + ++ G + L A G P P + W+K G + G A TL +++D Sbjct: 21 ANVSALRGSSITLTCTAEGLPVPAVVWKKGGA--------TLQQGGRAFTLS--STESAD 70 Query: 558 AAWYQCTAQNVAGS 571 + Y C A N+ G+ Sbjct: 71 SGRYDCVATNLKGT 84 >SB_36553| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 684 Score = 58.8 bits (136), Expect = 1e-07 Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 23/189 (12%) Query: 389 ALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447 ++AP F + +V+E C +G P P VTW + + + + +G+ Sbjct: 3 SVAPTFTSSLSSSHEVSENDDFNVTCSASGHPDPNVTWV-------NKLSGSAVAHGTGS 55 Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507 L + + +GV C A N A + + V P + VR GE Sbjct: 56 ATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTI----NVQYPPKITPIQNTTVRAGET 111 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 + L G PTP ++W K G H+ GG + A +D Y CTA N Sbjct: 112 ITLTCAVAGNPTPSVSWSKAGSG---------HSTGG-NVFTKAGATKADTGQYVCTAVN 161 Query: 568 -VAGSTATR 575 V G+T TR Sbjct: 162 TVTGNTQTR 170 Score = 51.2 bits (117), Expect = 2e-05 Identities = 66/245 (26%), Positives = 98/245 (40%), Gaps = 34/245 (13%) Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKA 389 K+ SGH T G + T A ++ T YV + +TQ R + + K Sbjct: 130 KAGSGHST------GGNVFTKAG-ATKADTGQYVCTAVNTVTGNTQTRTASTYVMVKYK- 181 Query: 390 LAPQFVKVCQDRDVTEGK-MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448 P + D+ V E + C G P P TWF RD ++V+ + + Sbjct: 182 --PSILSKSPDQTVNETTGFLKLTCISDGYPTPTFTWF------RDG----LVVSRTSVY 229 Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508 +VT S++G TC A N+ A ++ V K ++V+ ST N + Sbjct: 230 --YSNSVTRSEAGTYTCTATNEMMSDATTVQVTVNYKPEMVS-------STTNTSSWDRK 280 Query: 509 VLN--ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566 VL+ +A G P P+ITW G I I GG+ A D Y+C A Sbjct: 281 VLSLQCKARGVPLPQITWYNPGGQPITAGVSPI--SGGSQNQVATTRDAGDYGPYKCRAF 338 Query: 567 NVAGS 571 N+ GS Sbjct: 339 NLLGS 343 Score = 43.2 bits (97), Expect = 0.005 Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 10/100 (10%) Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899 ++ AP F + L+ ++SE + C +PDPN V W K+ S + T Sbjct: 2 ISVAPTFTSSLSSSHEVSENDDFNVTCSASGHPDPN--VTWV--NKLSGSAVAHGT---- 53 Query: 1900 GFAALDILTVYGEDSGEYTCKAINNL--GQAVSSIRLNVQ 1937 G A L +L + +G Y C+A N++ G + +NVQ Sbjct: 54 GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTINVQ 93 Score = 40.3 bits (90), Expect = 0.037 Identities = 45/186 (24%), Positives = 71/186 (38%), Gaps = 28/186 (15%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V+E +C G P P V W +KL + ++ TL + + G Y Sbjct: 18 VSENDDFNVTCSASGHPDPNVTWV--NKLSGSA----VAHGTGSATLSLLKIQRHQAGVY 71 Query: 4694 KCVAYNSA--GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751 +C A N G +T + V P P +TP+++ V G+ + P+ Sbjct: 72 QCQATNDVRRGAITQDVTINVQYP------PKITPIQNTTVRAGETITLTCAVAGNPTPS 125 Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA-TTAAGQVET---SAK 4807 + W + G+ G N G T + DTG + C A T G +T S Sbjct: 126 VSWSKAGS---------GHSTGGNVFTKAGAT-KADTGQYVCTAVNTVTGNTQTRTASTY 175 Query: 4808 LVVKSK 4813 ++VK K Sbjct: 176 VMVKYK 181 Score = 40.3 bits (90), Expect = 0.037 Identities = 67/293 (22%), Positives = 108/293 (36%), Gaps = 44/293 (15%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 PP T QN V +G+ + L V G V W K G G Sbjct: 95 PPKIT-PIQNTTVRAGETITLTCAVAGNPTPSVSWSKAGSG----------HSTGGNVFT 143 Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632 A D+G+Y C A+N+ T+ + P I+ D+ Sbjct: 144 KAGATKADTGQYVCTAVNTV------------TGNTQTRTASTYVMVKYKPSILSKSPDQ 191 Query: 4633 IVAEGQA-IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691 V E ++ +C G P PT W++ D L+ +SRT+ Y+ ++ + + G Sbjct: 192 TVNETTGFLKLTCISDGYPTPTFTWFR-DGLV-------VSRTSVYYSNSVTRS---EAG 240 Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751 Y C A N ++ A ++VT + + + + T + ++ + + + P Sbjct: 241 TYTCTATNE--MMSDATTVQVTVNYKPEMVSSTT---NTSSWDRKVLSLQCKARGVPLPQ 295 Query: 4752 IQWLREGALIPETPDFQMIHEGN-NAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803 I W G P T I G+ N V + D G + CRA G VE Sbjct: 296 ITWYNPGGQ-PITAGVSPISGGSQNQVATTRDA--GDYGPYKCRAFNLLGSVE 345 Score = 37.5 bits (83), Expect = 0.26 Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 21/177 (11%) Query: 1788 INEL-GEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRF 1846 +N+L G AV T + SL +H++ + + Q D R +DV + V P+ Sbjct: 41 VNKLSGSAVAHGT--GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTINVQYPPK- 97 Query: 1847 ITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI 1906 IT + T + G++ C + P P+ V W G SGH N F A Sbjct: 98 ITPIQNTT-VRAGETITLTCAVAGNPTPS--VSWSKAG----SGHS-TGGNVFTKAGAT- 148 Query: 1907 LTVYGEDSGEYTCKAIN----NLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959 D+G+Y C A+N N +S + V+ K SI+ S ++ E +L+ Sbjct: 149 ----KADTGQYVCTAVNTVTGNTQTRTASTYVMVKYKPSILSKSPDQTVNETTGFLK 201 Score = 37.1 bits (82), Expect = 0.35 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 8/97 (8%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 + AP FT+ L S ++ E + DPN + W L+ A T Sbjct: 2 ISVAPTFTSSLSSSHEVSENDDFNVTCSASGHPDPN--VTWVNK---LSGSAVAHGT--- 53 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 G TLS+ ++ +G+Y C+ATN + T + I Sbjct: 54 GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTI 90 Score = 35.9 bits (79), Expect = 0.80 Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 14/118 (11%) Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175 +++GTY+C ATN E+ V + KP + N D + +C Sbjct: 237 SEAGTYTCTATN-----EMMSDATTVQVTVNYKPEMVSSTTNTSSW-DRKVLSLQCKARG 290 Query: 3176 VDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231 V P +I WY+ GQP+ + + +S G +A T++ D G Y CRA+N G Sbjct: 291 VPLP--QITWYNPGGQPI--TAGVSPIS--GGSQNQVATTRDAGDYGPYKCRAFNLLG 342 Score = 35.1 bits (77), Expect = 1.4 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 17/139 (12%) Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163 G L +L + +G Y C+ATN + I+ + Q P T IQN ++ Sbjct: 54 GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTI----NVQYPPKITPIQNTT-VRA 108 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G++ C V +P + W G HST G V A D+G+YV Sbjct: 109 GETITLTCAV--AGNPTPSVSWSKAGS--GHST--------GGNVFTKAGATKADTGQYV 156 Query: 3224 CRAYNKYGEDFTRATINCY 3242 C A N + T + Y Sbjct: 157 CTAVNTVTGNTQTRTASTY 175 Score = 35.1 bits (77), Expect = 1.4 Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 15/134 (11%) Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEAT 2000 S+++ +H++ + + Q +D R QD + V+ P PI+N V G + L T Sbjct: 59 SLLKIQRHQAGVYQCQ-ATNDVRRGAITQDVTINVQYPPKITPIQNTTVRAGETITL--T 115 Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV-G 2059 +PT V W G GH G A DTG Y+C A N V G Sbjct: 116 CAVAGNPTPSVSWSKAG----SGH------STGGNVFTKAGATKADTGQYVCTAVNTVTG 165 Query: 2060 EAVT-TSSVKVDAK 2072 T T+S V K Sbjct: 166 NTQTRTASTYVMVK 179 Score = 34.7 bits (76), Expect = 1.9 Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 12/115 (10%) Query: 3825 IVSTPPKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883 ++S P F + + S H V E++ C DP + W KL S + T Sbjct: 1 MISVAPTFTSSLSSSHEVSENDDFNVTCSASGHPDPN--VTWVN--KLSGSAVAHGT--- 53 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDF--GEDFTKATISCKKLPDII-LQNQVPR 3935 G +L +L + +G Y C+A ND G TI+ + P I +QN R Sbjct: 54 -GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTINVQYPPKITPIQNTTVR 107 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 8/80 (10%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F ++L+S + E D + C DP++T W + K+ H G Sbjct: 6 PTFTSSLSSSHEVSENDDFNVTCSASGHPDPNVT--WVN---KLSGS---AVAHGTGSAT 57 Query: 2169 LDILYTYAEDSGTYMCKATN 2188 L +L +G Y C+ATN Sbjct: 58 LSLLKIQRHQAGVYQCQATN 77 Score = 33.1 bits (72), Expect = 5.7 Identities = 14/31 (45%), Positives = 21/31 (67%) Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794 +AG YTC ATN+ S TT ++T + K ++V Sbjct: 238 EAGTYTCTATNEMMSDATTVQVTVNYKPEMV 268 Score = 32.3 bits (70), Expect = 9.9 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 3/48 (6%) Query: 4111 PVFVS-LPDAVTVEEGEWARFCCRVTGHPKPRVMWL--LNGNTIVNGS 4155 P F S L + V E + C +GHP P V W+ L+G+ + +G+ Sbjct: 6 PTFTSSLSSSHEVSENDDFNVTCSASGHPDPNVTWVNKLSGSAVAHGT 53 Score = 32.3 bits (70), Expect = 9.9 Identities = 35/125 (28%), Positives = 52/125 (41%), Gaps = 17/125 (13%) Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231 I+ P + P+ N V G+ I L C + G+PT V W G + G T Sbjct: 90 INVQYPPKITPIQNTT-VRAGETITLTCAVA--GNPTPSVSWSKAGSGHSTGGNVFTKAG 146 Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHL-GSAHT---SAIVRVIERSDIVTDTQNEQAIEQ 1287 AT ADTG+Y AVN + G+ T S V V + I++ + ++ E Sbjct: 147 ----------ATKADTGQYVCTAVNTVTGNTQTRTASTYVMVKYKPSILSKSPDQTVNET 196 Query: 1288 IQLLE 1292 L+ Sbjct: 197 TGFLK 201 Score = 32.3 bits (70), Expect = 9.9 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 13/112 (11%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 KP + DQ + GF + G T W +DG V SR + +++ Sbjct: 181 KPSILSKSPDQTVNETTGFLKLTCISD--GYPTPTFTWFRDGLVV---SRTSVYYS---- 231 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEK 1019 SVT +AG YTC A N + T+ +T+ K ++++ + + ++ Sbjct: 232 ----NSVTRSEAGTYTCTATNEMMSDATTVQVTVNYKPEMVSSTTNTSSWDR 279 >SB_37863| Best HMM Match : I-set (HMM E-Value=3.1e-14) Length = 188 Score = 58.0 bits (134), Expect = 2e-07 Identities = 35/145 (24%), Positives = 73/145 (50%), Gaps = 5/145 (3%) Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442 ++I + P+ ++ +D + E +FD ++ P EV W+ +I D + + Sbjct: 39 LDIVKSKSKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQ 98 Query: 443 NES-GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL- 500 +E G +++ I ++ L D G VA N G+T+ + L V KE+++AP+F R + + Sbjct: 99 DEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV--KEKLIAPEFEGRETEVP 156 Query: 501 -NVREGEPVVLNARAVGTPTPRITW 524 +E + ++ G P+P +++ Sbjct: 157 FRAKEKSDLEVSYNINGKPSPDVSY 181 Score = 50.4 bits (115), Expect = 3e-05 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 2/98 (2%) Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE- 4677 + + PEI+E +KD E +F KI P V+WY I + +++ ++ Sbjct: 44 SKSKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDG 103 Query: 4678 -YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714 Y++ I++ ED G YK VA+N G+ + A+L V + Sbjct: 104 TYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKE 141 Score = 47.2 bits (107), Expect = 3e-04 Identities = 34/114 (29%), Positives = 50/114 (43%), Gaps = 5/114 (4%) Query: 1027 SRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086 S YS + VK KP L +K I G+ A F+ +++ VEWY +I Sbjct: 32 STYSSANLDIVKSKSKPEILETMKDAEGIETGK-AKFDVKIKAYPKAE--VEWYHRSARI 88 Query: 1087 TSANRIQTYHDF--GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138 R D G ++ I +R ED G Y +VA N G+ A +TV+ + Sbjct: 89 YDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142 Score = 46.4 bits (105), Expect = 6e-04 Identities = 24/85 (28%), Positives = 40/85 (47%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 S P + K+A + G AKF+ K++ P V W + A + + +Y + +E+ G Sbjct: 46 SKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTY 105 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154 S+ I + D G Y A N G+ Sbjct: 106 SVTINDLRLEDCGTYKIVAFNDIGK 130 Score = 45.6 bits (103), Expect = 0.001 Identities = 49/195 (25%), Positives = 79/195 (40%), Gaps = 22/195 (11%) Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524 K L ++V + D + +N G+ SANL + + + + P T ++ Sbjct: 6 KCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSK-------PEILETMKDAE 58 Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL--EEDGTYTLLILEAYPQDSG 4582 + D K+ +V W ++ R + EEDGTY++ I + +D G Sbjct: 59 GIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCG 118 Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDK-PKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641 Y+ VA N G+ AE V K+K P+ + E P + K E +E Sbjct: 119 TYKIVAFNDIGKTSERAELTV-----KEKLIAPEFEGR----ETEVPFRAK---EKSDLE 166 Query: 4642 FSCKIVGKPLPTVQW 4656 S I GKP P V + Sbjct: 167 VSYNINGKPSPDVSY 181 Score = 42.7 bits (96), Expect = 0.007 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%) Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161 + +SK++ P + ++ DA +E G+ A+F ++ +PK V W I +G RY LT Sbjct: 41 IVKSKSK-PEILETMKDAEGIETGK-AKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQ 98 Query: 4162 ---DGMYHFDIPKTRQYDTGKIEVI 4183 DG Y I R D G +++ Sbjct: 99 DEEDGTYSVTINDLRLEDCGTYKIV 123 Score = 42.7 bits (96), Expect = 0.007 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 5/100 (5%) Query: 765 QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSI 822 ++ +P+ + ++D ++ G+ A F+ ++ P VEWY I R +T Sbjct: 43 KSKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQD 99 Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862 G S+ I LR ED G+Y + A N +G+ A + V Sbjct: 100 EEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV 139 Score = 42.3 bits (95), Expect = 0.009 Identities = 26/90 (28%), Positives = 48/90 (53%), Gaps = 5/90 (5%) Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTH 2429 ++ +P + +++ + I+ G+ A FD ++ P +VEW+ I D R +T+ Sbjct: 44 SKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDE 100 Query: 2430 DFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 + G S+TI+ +R ED G Y A N +G+ Sbjct: 101 EDGTYSVTINDLRLEDCGTYKIVAFNDIGK 130 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 5/96 (5%) Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FG 2165 +P L + E ++ G +A F+ +++ P ++W+H +I G RY T D G Sbjct: 47 KPEILETMKDAEGIETG-KAKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDEEDG 103 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 ++ I ED GTY A N +G+ L V Sbjct: 104 TYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV 139 Score = 41.5 bits (93), Expect = 0.016 Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 6/111 (5%) Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288 S +++ + K S P + ++ + GK A F+ +++ P +E+YH + Sbjct: 36 SANLDIVKSK-SKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDG 91 Query: 2289 ARFHITFDF--GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337 R+ +T D G S+ I ED G Y + A N +G + +TV K Sbjct: 92 GRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142 Score = 41.5 bits (93), Expect = 0.016 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Query: 3840 TVEESEGV---RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM--GFVSLDILYV 3894 T++++EG+ + + V+ K PK +EWY + G RY D G S+ I + Sbjct: 53 TMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDL 112 Query: 3895 YAEDSGEYICRAVNDFGEDFTKATISCKK 3923 ED G Y A ND G+ +A ++ K+ Sbjct: 113 RLEDCGTYKIVAFNDIGKTSERAELTVKE 141 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 5/105 (4%) Query: 902 VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--IT 959 + +S KPE +KD I E G A F+ +++ + VEW + R +T Sbjct: 41 IVKSKSKPEILETMKDAEGI-ETGKAKFDVKIKAYPKA--EVEWYHRSARIYDGGRYCLT 97 Query: 960 TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 G ++TI + + D G Y A+N IG+ + A LT+ K Sbjct: 98 QDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142 Score = 39.5 bits (88), Expect = 0.065 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 4/97 (4%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYV 1768 P MKD E A F+ ++ PK VEW I R LT + G Sbjct: 48 PEILETMKDAEGIETGKAKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDEEDGTY 105 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805 ++ + + ED GTY A N++G+ + L V+ K Sbjct: 106 SVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142 Score = 38.3 bits (85), Expect = 0.15 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 4/85 (4%) Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFV 1635 P ++K+ E E +A F+ ++ A +VEWYH + + G R+ T+ G Sbjct: 48 PEILETMKDAEGIETGKAKFDVKIKAYPKA--EVEWYHRSARIYDGGRYCLTQDEEDGTY 105 Query: 1636 ALDIMSCLPEDSGTYTCRAINALGE 1660 ++ I ED GTY A N +G+ Sbjct: 106 SVTINDLRLEDCGTYKIVAFNDIGK 130 Score = 38.3 bits (85), Expect = 0.15 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDDSGIYTCKATNLL 2723 V+ + P ++EW+ + G R T D G +++IN LR +D G Y A N + Sbjct: 69 VKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDI 128 Query: 2724 GEAVSTASIKIEDR 2737 G+ A + ++++ Sbjct: 129 GKTSERAELTVKEK 142 Score = 37.9 bits (84), Expect = 0.20 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 4/88 (4%) Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSD--FGFVTLDLVDVYERDSGIYTCKAYNKR 2992 V+ K P ++EWY + G R+ LT D G ++ + D+ D G Y A+N Sbjct: 69 VKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDI 128 Query: 2993 GEAFTSSTVYCTSKDNLIERTQHPKGTE 3020 G+ TS T K+ LI + TE Sbjct: 129 GK--TSERAELTVKEKLIAPEFEGRETE 154 Score = 37.1 bits (82), Expect = 0.35 Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 4/113 (3%) Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021 S Y A D KP+ + +K+AE E + + P VEWY + Sbjct: 32 STYSSANLDIVKSKSKPEILETMKDAEGIETGKAKFDVKIKAY--PKAEVEWYHRSARIY 89 Query: 2022 QGHRFKTTYDF--GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 G R+ T D G ++ I ED GTY A N +G+ + + V K Sbjct: 90 DGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 5/102 (4%) Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD- 1231 SKSKP ++ + + + GK + +++ P VEW+H + G R+ D Sbjct: 44 SKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDE 100 Query: 1232 -FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272 G ++ I D G Y + A N +G A + V E+ Sbjct: 101 EDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142 Score = 35.5 bits (78), Expect = 1.1 Identities = 29/131 (22%), Positives = 46/131 (35%), Gaps = 4/131 (3%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L V LSD G T +N G T L++++ + P+ +E E Sbjct: 9 LNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKS--KPEILETMKDAEGIETGKAK 66 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQN 567 + + P + W I + D G ++ I + D Y+ A N Sbjct: 67 FDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFN 126 Query: 568 VAGSTATRARL 578 G T+ RA L Sbjct: 127 DIGKTSERAEL 137 Score = 34.7 bits (76), Expect = 1.9 Identities = 18/84 (21%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322 S P+I + ++++ E A+F V++ P+ V W+ R+ + ++ + T Sbjct: 46 SKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTY 105 Query: 323 -LRVRNTQKSDSGHYTLLAENPNG 345 + + + + D G Y ++A N G Sbjct: 106 SVTINDLRLEDCGTYKIVAFNDIG 129 Score = 34.3 bits (75), Expect = 2.5 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDF---QIHT 4461 VK P + M+ E +A+F+V+ P ++WY + I + + Q Sbjct: 42 VKSKSKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEE 101 Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503 T S+ I + +ED + VA N G A L V+EK Sbjct: 102 DGTYSV-TINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 6/106 (5%) Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471 + + K K P + + E + G+ A F+ ++ P +VEWY + G R+ Sbjct: 41 IVKSKSK-PEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCL 96 Query: 3472 FCDF--GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515 D G + I+ ED G Y A+N+ G+ A + V+ K Sbjct: 97 TQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142 >SB_51604| Best HMM Match : I-set (HMM E-Value=2.3e-21) Length = 152 Score = 58.0 bits (134), Expect = 2e-07 Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 5/127 (3%) Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKD--KPKPQTKAANAPPEIIEPLKDKI-VAE 4636 + G Y CVA N G+ R + V P P P T + P + + D + V E Sbjct: 17 EGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLE 76 Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 I C G P P V W + I +++ TAD T+ I A D G + C Sbjct: 77 DSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRV--TADGVTMLIDGAVVSDTGSFTCE 134 Query: 4697 AYNSAGR 4703 A N AG+ Sbjct: 135 AENFAGK 141 Score = 56.4 bits (130), Expect = 5e-07 Identities = 26/55 (47%), Positives = 31/55 (56%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM 4164 P V + + D VTV E R C TG P PRV W NGN I G RY++T DG+ Sbjct: 62 PRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTADGV 116 Score = 55.6 bits (128), Expect = 9e-07 Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 20/144 (13%) Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE--KEQVVAPK------ 492 L++ SG+ L I T + GV TCVA N G+ L+VIE K +++AP Sbjct: 3 LIDNSGS--LTIRGAT--EGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPL 58 Query: 493 ------FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546 + + V E + + A G P PR+TW+++G I R+ DG Sbjct: 59 SGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTADG--V 116 Query: 547 TLDIPRAKASDAAWYQCTAQNVAG 570 T+ I A SD + C A+N AG Sbjct: 117 TMLIDGAVVSDTGSFTCEAENFAG 140 Score = 49.6 bits (113), Expect = 6e-05 Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 4/91 (4%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 PR T+ I DN+ V E + C G P R+ W NG + G R D + Sbjct: 62 PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYRVTAD--GVT 117 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785 + ID D G +TC A N G T+ + Sbjct: 118 MLIDGAVVSDTGSFTCEAENFAGKDKATSAV 148 Score = 46.8 bits (106), Expect = 4e-04 Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 4/84 (4%) Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045 N V E + + T + P RV W NG + QG R++ T D + +D A Sbjct: 71 NVTVLEDSTIRIVCNATGL--PAPRVTWRQNGNAISQGGRYRVTADGVTMLID--GAVVS 126 Query: 2046 DTGTYMCKATNAVGEAVTTSSVKV 2069 DTG++ C+A N G+ TS+V V Sbjct: 127 DTGSFTCEAENFAGKDKATSAVIV 150 Score = 45.6 bits (103), Expect = 0.001 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%) Query: 3816 ISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875 ++ +P P+ TP I + TV E +R C P R+ W +NG + G Sbjct: 49 LAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQG 106 Query: 3876 HRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922 RYR D + +D V D+G + C A N G+D + + K Sbjct: 107 GRYRVTADGVTMLIDGAVV--SDTGSFTCEAENFAGKDKATSAVIVK 151 Score = 44.8 bits (101), Expect = 0.002 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 16/135 (11%) Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNL---PALTPLR-----------DIVVYEGQ 4736 G Y CVA N G+ + L V +P + L P PL ++ V E Sbjct: 19 GVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDS 78 Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796 + T P + W + G I + +++ +G +LI DTG+FTC A Sbjct: 79 TIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAE 136 Query: 4797 TAAGQVETSAKLVVK 4811 AG+ + ++ ++VK Sbjct: 137 NFAGKDKATSAVIVK 151 Score = 41.5 bits (93), Expect = 0.016 Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 11/136 (8%) Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP--------PSFTLT-AQNVNVTS 4527 + V+ VA N G + ++ L V E R+ P P T+ + NV V Sbjct: 17 EGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLE 76 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 +R+ TG V W +NG + R ++ DG T+LI A D+G + C Sbjct: 77 DSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTA-DGV-TMLIDGAVVSDTGSFTCE 134 Query: 4588 AINSAGEARCDAECVV 4603 A N AG+ + + +V Sbjct: 135 AENFAGKDKATSAVIV 150 Score = 41.5 bits (93), Expect = 0.016 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Query: 392 PQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 P+ V D V E R C TG P P VTW N I +++ + + Sbjct: 62 PRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTAD---GVTM 118 Query: 451 MITNVTLSDSGVVTCVARNKSGE 473 +I +SD+G TC A N +G+ Sbjct: 119 LIDGAVVSDTGSFTCEAENFAGK 141 Score = 40.7 bits (91), Expect = 0.028 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%) Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242 +S+ V E I + C G P RV W NG +++ G R++ D V + I A Sbjct: 68 ISDNVTVLEDSTIRIVCNAT--GLPAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGA 123 Query: 1243 TSADTGEYTVRAVNHLG-SAHTSAIV 1267 +DTG +T A N G TSA++ Sbjct: 124 VVSDTGSFTCEAENFAGKDKATSAVI 149 Score = 40.7 bits (91), Expect = 0.028 Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 2/55 (3%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G P+ R W NG + G R+R T D VT+ I+ V +D G + C+A N AG Sbjct: 88 GLPAPRVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAG 140 Score = 40.3 bits (90), Expect = 0.037 Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 24/153 (15%) Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDE 1438 + GVYTC A N G+ + L VI + + + P + L T R T +I + Sbjct: 17 EGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIP----LSGTPRV--TIVISD 70 Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498 +VT V+E + C + +V W +NG ++ G R+R D Sbjct: 71 NVT--------------VLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTAD 114 Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531 + +D + D+G +TC A N G D+ + Sbjct: 115 GVTMLID--GAVVSDTGSFTCEAENFAGKDKAT 145 Score = 40.3 bits (90), Expect = 0.037 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 4/90 (4%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897 + ++ PR ++ + E + C P P RV W NG + G RYR + Sbjct: 56 IPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTA 113 Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927 D +D V D+G +TC+A N G+ Sbjct: 114 DGVTMLIDGAVV--SDTGSFTCEAENFAGK 141 Score = 39.9 bits (89), Expect = 0.049 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000 P ++ W NG + QG R+++T+D VT+ + D+G +TC+A N G+ +S Sbjct: 90 PAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGAVVSDTGSFTCEAENFAGKDKATSA 147 Query: 3001 V 3001 V Sbjct: 148 V 148 Score = 39.5 bits (88), Expect = 0.065 Identities = 19/64 (29%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P ++ W +NG ++ G R + T D VT+ I+ D+G +TC+A N G+ +T++ Sbjct: 90 PAPRVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGKDKATSA 147 Query: 2732 IKIE 2735 + ++ Sbjct: 148 VIVK 151 Score = 38.7 bits (86), Expect = 0.11 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 2/69 (2%) Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N + E + + +G P PRVTW +NG + ++ + T + T+ + SD+ Sbjct: 71 NVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRV--TADGVTMLIDGAVVSDT 128 Query: 334 GHYTLLAEN 342 G +T AEN Sbjct: 129 GSFTCEAEN 137 Score = 38.3 bits (85), Expect = 0.15 Identities = 30/131 (22%), Positives = 53/131 (40%), Gaps = 17/131 (12%) Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQ-------------KPRFTTHIQNIEGLK 3162 T+ G Y+C A N GQ + L+ ++ K + PR T I + + Sbjct: 16 TEGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVL 75 Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222 + + C + P ++ W NG + R + +D +++D A D+G + Sbjct: 76 EDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTADGVTMLIDGAVVS--DTGSF 131 Query: 3223 VCRAYNKYGED 3233 C A N G+D Sbjct: 132 TCEAENFAGKD 142 Score = 37.5 bits (83), Expect = 0.26 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%) Query: 3554 SGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG 3613 SG P ++ + E+S+ C + + RV W NG + G R + D G Sbjct: 59 SGTPRVTIVISDNVTVLEDSTIRIVCNATGL--PAPRVTWRQNGNAISQGGRYRVTAD-G 115 Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 +L I G D G +TC+A N G+ + + VK Sbjct: 116 VTML-IDGAVVSDTGSFTCEAENFAGKDKATSAVIVK 151 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 4/84 (4%) Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378 N+ +E + + + C G RV W NG I G R+R D V + + Sbjct: 71 NVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYR--VTADGVTMLIDGAVVS 126 Query: 1379 DSGVYTCQATNQLGEAVTSCALRV 1402 D+G +TC+A N G+ + A+ V Sbjct: 127 DTGSFTCEAENFAGKDKATSAVIV 150 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 4/94 (4%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 P T+ +S +N+ E++ T P +V W NG ++ G R+R D G + Sbjct: 62 PRVTIVIS--DNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTAD-GVTM 118 Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513 L I D+G + C A N G+ T+++ V+ Sbjct: 119 L-IDGAVVSDTGSFTCEAENFAGKDKATSAVIVK 151 Score = 36.7 bits (81), Expect = 0.46 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 5/92 (5%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032 PR I +++E T + C G P +V W NG + R+ D V Sbjct: 62 PRVTIVISDNVTVLEDSTIRIVCNAT--GLPAPRVTWRQNGNAISQGGRYRVTADG--VT 117 Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDE-TKAVI 4063 M D+G + C A N G D+ T AVI Sbjct: 118 MLIDGAVVSDTGSFTCEAENFAGKDKATSAVI 149 Score = 36.3 bits (80), Expect = 0.61 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840 +N+ E I CN P ++ W N + G RY+ T D V++ I Sbjct: 70 DNVTVLEDSTIRIVCNATGL--PAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGAVV 125 Query: 2841 EDSGIYTCKATNSKG 2855 D+G +TC+A N G Sbjct: 126 SDTGSFTCEAENFAG 140 Score = 35.9 bits (79), Expect = 0.80 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 22/149 (14%) Query: 2044 AEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEE 2103 A + G Y C A N G+ TS LD ++ ++ K + P P+ Sbjct: 15 ATEGGVYTCVAANDQGQDRATS----------ILDVIEPRKPKILA-------PSPLTIP 57 Query: 2104 QPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD 2163 G V + ++ L E C + P +T W NG I G RYR T D Sbjct: 58 LSGTPRVTIVISDNVTVL-EDSTIRIVCNATGLPAPRVT--WRQNGNAISQGGRYRVTAD 114 Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGE 2192 + +D D+G++ C+A N G+ Sbjct: 115 GVTMLID--GAVVSDTGSFTCEAENFAGK 141 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 4/90 (4%) Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336 P + P+ I D ++E + + P +V W NG + G RYR D Sbjct: 57 PLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTAD 114 Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRD 3366 G+ +L I ++G + C A N G+D Sbjct: 115 -GVTML-IDGAVVSDTGSFTCEAENFAGKD 142 Score = 34.3 bits (75), Expect = 2.5 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 4/84 (4%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P T V D V + E + TG + + W NG I R R V A G+ + Sbjct: 62 PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYR-VTADGVTM 118 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQ 3131 L I G +D+G+++C A N G+ Sbjct: 119 L-IDGAVVSDTGSFTCEAENFAGK 141 Score = 33.1 bits (72), Expect = 5.7 Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 10/109 (9%) Query: 2356 LESAEPFKRPEIPEPVTRQRPVFTQPLQNI---DNIQ--EGQTAHFDCRLIPVGDPTLKV 2410 L+ EP ++P+I P P+ P I DN+ E T C G P +V Sbjct: 38 LDVIEP-RKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRV 94 Query: 2411 EWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 W +N I R T D V+M I D G + C A N G+ Sbjct: 95 TWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGK 141 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P RV W +NG I R D + ++ V+ D+G++TC A N G+ + Sbjct: 88 GLPAPRVTWRQNGNAISQGGRYRVTADGVTMLIDGAVVS--DTGSFTCEAENFAGKDKAT 145 Query: 1798 STLFVQ 1803 S + V+ Sbjct: 146 SAVIVK 151 >SB_39029| Best HMM Match : ig (HMM E-Value=6e-10) Length = 439 Score = 58.0 bits (134), Expect = 2e-07 Identities = 47/178 (26%), Positives = 70/178 (39%), Gaps = 12/178 (6%) Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 GQ+ C + G P P++ W K D L+ + +++ L+ S D G+Y C+ Sbjct: 20 GQSRRLLCCMGGSPRPSITWLKDDSLLDIKENYKLEVFEQGQILQNSNVLKSDAGNYTCI 79 Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD---IVVYEGQPAQFKTQITSKIKPTIQ 4753 N G + + V Q Q D P + D ++ QITS KP + Sbjct: 80 GSNPLGNASHSFYFTV-QERQWDFNPIIQMHADQWNATIFSN--ITLTCQITSSKKPFVS 136 Query: 4754 WLR-EGALIPETPDFQMIHEGN-----NAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805 W+ + P P + I N L I N ED G + CR+T A G S Sbjct: 137 WIHIKNFTTPSFPRVRHILTNNGGDKWTTSLPIVNVSYEDGGKYICRSTNAIGHKNVS 194 Score = 56.4 bits (130), Expect = 5e-07 Identities = 42/171 (24%), Positives = 66/171 (38%), Gaps = 7/171 (4%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 G+ R C + G P P +TW +D + N+K+ V E G L +NV SD+G TC Sbjct: 20 GQSRRLLCCMGGSPRPSITWLKDDSLLDIKENYKLEVFEQG-QILQNSNVLKSDAGNYTC 78 Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW- 524 + N G + V E++ P N + L + + P ++W Sbjct: 79 IGSNPLGNASHSFYFTVQERQWDFNPIIQMHADQWNATIFSNITLTCQITSSKKPFVSWI 138 Query: 525 --QKDGVPIIPNPELRIHTDGG---ASTLDIPRAKASDAAWYQCTAQNVAG 570 + P P + +GG ++L I D Y C + N G Sbjct: 139 HIKNFTTPSFPRVRHILTNNGGDKWTTSLPIVNVSYEDGGKYICRSTNAIG 189 Score = 47.6 bits (108), Expect = 2e-04 Identities = 40/164 (24%), Positives = 68/164 (41%), Gaps = 11/164 (6%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P P I W +++ + ++++ F IL V D+ + + N G A S Sbjct: 31 GSPRPSITWLKDDSLLDIKENYKLEVFEQGQILQNSNVLKSDAGNYTCIGSNPLGNASHS 90 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--LKNGKK 4553 V+E++ P + A N T + L ++T +K V W +KN Sbjct: 91 FYFTVQERQWD-----FNPIIQMHADQWNATIFSNITLTCQITSSKKPFVSWIHIKNFTT 145 Query: 4554 VQ-PDIRNKILEEDG---TYTLLILEAYPQDSGKYECVAINSAG 4593 P +R+ + G T +L I+ +D GKY C + N+ G Sbjct: 146 PSFPRVRHILTNNGGDKWTTSLPIVNVSYEDGGKYICRSTNAIG 189 Score = 46.8 bits (106), Expect = 4e-04 Identities = 22/68 (32%), Positives = 34/68 (50%) Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348 + G+PRP +TW K+ L +++ L+ N KSD+G+YT + NP G Sbjct: 29 MGGSPRPSITWLKDDSLLDIKENYKLEVFEQGQILQNSNVLKSDAGNYTCIGSNPLGNAS 88 Query: 349 TSGYLAVE 356 S Y V+ Sbjct: 89 HSFYFTVQ 96 Score = 37.1 bits (82), Expect = 0.35 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 2/69 (2%) Query: 2672 PNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 P I W K+ L K F+ G + + N L++D +G YTC +N LG A + Sbjct: 33 PRPSITWLKDDSLLDIKENYKLEVFEQGQILQNSNVLKSD-AGNYTCIGSNPLGNASHSF 91 Query: 2731 SIKIEDRHW 2739 +++R W Sbjct: 92 YFTVQERQW 100 Score = 36.3 bits (80), Expect = 0.61 Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 5/101 (4%) Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899 QAP F+T LN + GQS C + P P+ + W + +L Y+ Sbjct: 2 QAP-FVTILNSTELILALTGQSRRLLCCMGGSPRPS--ITWLKDDSLLDIKENYKLEVFE 58 Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940 L V D+G YTC N LG A S VQ ++ Sbjct: 59 QGQILQNSNVLKSDAGNYTCIGSNPLGNASHSFYFTVQERQ 99 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/97 (20%), Positives = 40/97 (41%) Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776 QA + L I+ GQ + + +P+I WL++ +L+ ++++ Sbjct: 2 QAPFVTILNSTELILALTGQSRRLLCCMGGSPRPSITWLKDDSLLDIKENYKLEVFEQGQ 61 Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 +L N + D G +TC + G S V+ + Sbjct: 62 ILQNSNVLKSDAGNYTCIGSNPLGNASHSFYFTVQER 98 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156 G+P P ++W + + L Y + EQ G + L + D G YTC N G A Sbjct: 31 GSPRPSITWLKDDSLLDIKENYKLEVFEQ-GQI-LQNSNVLKSDAGNYTCIGSNPLGNAS 88 Query: 157 CSVY 160 S Y Sbjct: 89 HSFY 92 >SB_58150| Best HMM Match : ig (HMM E-Value=3.7e-24) Length = 456 Score = 56.8 bits (131), Expect = 4e-07 Identities = 49/199 (24%), Positives = 79/199 (39%), Gaps = 9/199 (4%) Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581 N+ + +G ++L G V W + G + + R ++++ D TL ++E P DS Sbjct: 30 NITLLAGSTLKLRCPSDGLPKPFVKWTRYGVRAMSNER-QLIDSDSD-TLTMVEVLPYDS 87 Query: 4582 GKYECVAINSAGEARCDAECVV---SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638 G+ C N G + + V P+ + +N P + Sbjct: 88 GEVSCTVTNLRGSDKKTSSITVLEPFAPSINTSDETVVSLSNLDPVTVRAGALLTTFLTT 147 Query: 4639 AIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSR-TADEYTLRISEAFPEDEGDYKCV 4696 I CK G P P+V W + GDKL M R + + I++A P D G Y C Sbjct: 148 NITLVCKARGLPKPSVSWTRAGDKL--SHWLASMGRVSTSNGNVTITQAEPNDAGMYLCT 205 Query: 4697 AYNSAGRVTVAAKLKVTQP 4715 A N G + + L +P Sbjct: 206 ARNLLGVASARSTLYFKEP 224 Score = 52.0 bits (119), Expect = 1e-05 Identities = 52/190 (27%), Positives = 78/190 (41%), Gaps = 21/190 (11%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 G + C G P P V W +R N + L+ +S + L + V DSG V+C Sbjct: 36 GSTLKLRCPSDGLPKPFVKW--TRYGVRAMSNERQLI-DSDSDTLTMVEVLPYDSGEVSC 92 Query: 466 VARNKSGETAFQCRLNVIEK---------EQVVA-----PKFVERFSTLNVREGEPVVLN 511 N G + V+E E VV+ P V + L + L Sbjct: 93 TVTNLRGSDKKTSSITVLEPFAPSINTSDETVVSLSNLDPVTVRAGALLTTFLTTNITLV 152 Query: 512 ARAVGTPTPRITWQKDGVPIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 +A G P P ++W + G + R+ T G T I +A+ +DA Y CTA+N+ Sbjct: 153 CKARGLPKPSVSWTRAGDKLSHWLASMGRVSTSNGNVT--ITQAEPNDAGMYLCTARNLL 210 Query: 570 GSTATRARLY 579 G + R+ LY Sbjct: 211 GVASARSTLY 220 Score = 44.4 bits (100), Expect = 0.002 Identities = 27/62 (43%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Query: 94 KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 K RG P P VSWTR L R + G+V+ I Q P D G Y CTARN G Sbjct: 154 KARGLPKPSVSWTRAGDKLSHWLASMGRVSTSNGNVT--ITQAEPNDAGMYLCTARNLLG 211 Query: 154 EA 155 A Sbjct: 212 VA 213 Score = 44.4 bits (100), Expect = 0.002 Identities = 62/295 (21%), Positives = 114/295 (38%), Gaps = 22/295 (7%) Query: 291 GNPRPRVTWFKNGQRLIN--SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348 G P+P V+W + G +L + ++ + T++ + T + + +D+G Y A N G Sbjct: 157 GLPKPSVSWTRAGDKLSHWLASMGRVSTSNGNVT--ITQAEPNDAGMYLCTARNLLGVAS 214 Query: 349 TSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKM 408 L + P ++ Q+ R + I + L + + Sbjct: 215 ARSTLYFKEPRGPFIVTQKKSLTIFNATRPIDMTIGTNLTTLVNTTITIRCQASGDPAPD 274 Query: 409 TRFDCRVTGRPYPE-VTWFINDRQI--RDDYNHKILVNESGNHALM-ITNVTLSDSGVVT 464 T + R +P+P+ VT D I KI ++ +L TN+T++ ++ Sbjct: 275 TAWQ-RPGNKPFPKHVTIDREDLTIDMAPGLPPKITRSQEVITSLTRFTNLTVTIGSTIS 333 Query: 465 CVARNKSG-----ETAFQCRLN----VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515 +A ++ F ++N VI + AP +TL G + +N +A Sbjct: 334 VLAGSRLKLLCPVTEPFGPKINSTRSVIIQLDSQAPITTMAGATLTTISGVDLTINCQAT 393 Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 G P P + W +G +I + + L I A +D Y CTA + G Sbjct: 394 GLPVPDVAWFLEGERVISQGGISVEN----GKLRIRNAGNADGGRYVCTANSSVG 444 Score = 40.3 bits (90), Expect = 0.037 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339 G D Q +G P P V WF G+R+I+ I+ N LR+RN +D G Y Sbjct: 383 GVDLTINCQATGLPVPDVAWFLEGERVISQGG---ISVEN-GKLRIRNAGNADGGRYVCT 438 Query: 340 AENPNG 345 A + G Sbjct: 439 ANSSVG 444 Score = 38.7 bits (86), Expect = 0.11 Identities = 83/404 (20%), Positives = 134/404 (33%), Gaps = 41/404 (10%) Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494 DG P P +KW R S + Q+ + ++ ++ + + V V RG K Sbjct: 46 DGLPKPFVKWTRYGVRAM-SNERQLIDSDSDTLTMVEVLPYDSGEVSCTVTNLRGSDKKT 104 Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR--LDTKVT------GTKPIDVY 4546 S+ V+E V V +G L+ L T +T G V Sbjct: 105 SSITVLEPFAPSINTSDETVVSLSNLDPVTVRAGALLTTFLTTNITLVCKARGLPKPSVS 164 Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606 W + G K+ + + + I +A P D+G Y C A N G A + P Sbjct: 165 WTRAGDKLSHWLASMGRVSTSNGNVTITQAEPNDAGMYLCTARNLLGVASARSTLYFKEP 224 Query: 4607 ATK--DKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663 K NA I + + I C+ G P P W + Sbjct: 225 RGPFIVTQKKSLTIFNATRPIDMTIGTNLTTLVNTTITIRCQASGDPAPDTAWQRPGNKP 284 Query: 4664 KPSKYFQMSRTADEYTLRISEAFPE------------DEGDYKCVAYNSAGRVTVAAKLK 4711 P K+ + R ++ T+ ++ P V S V ++LK Sbjct: 285 FP-KHVTIDR--EDLTIDMAPGLPPKITRSQEVITSLTRFTNLTVTIGSTISVLAGSRLK 341 Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ------ITSKIKPTIQWLREGALIPETP 4765 + P P + R +++ A T S + TI G +P+ Sbjct: 342 LLCPVTEPFGPKINSTRSVIIQLDSQAPITTMAGATLTTISGVDLTINCQATGLPVPDVA 401 Query: 4766 DF----QMIHEG----NNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 F ++I +G N L I N D G + C A ++ G+ Sbjct: 402 WFLEGERVISQGGISVENGKLRIRNAGNADGGRYVCTANSSVGE 445 Score = 35.5 bits (78), Expect = 1.1 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 5/62 (8%) Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471 +C+ TG P P+V WF+ ++ + E+G L I N +D G C A + Sbjct: 389 NCQATGLPVPDVAWFLEGERVISQGGISV---ENGK--LRIRNAGNADGGRYVCTANSSV 443 Query: 472 GE 473 GE Sbjct: 444 GE 445 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 1738 GDPKLRVEWLRNGVPIE----ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793 G PK V W R G + + R++T + G V + P D+G Y C A N LG Sbjct: 157 GLPKPSVSWTRAGDKLSHWLASMGRVSTSN--GNVTITQ--AEPNDAGMYLCTARNLLGV 212 Query: 1794 AVTSSTLFVQSKASLQLESQHES 1816 A STL+ + + +Q +S Sbjct: 213 ASARSTLYFKEPRGPFIVTQKKS 235 >SB_32327| Best HMM Match : ig (HMM E-Value=7.9e-23) Length = 932 Score = 56.8 bits (131), Expect = 4e-07 Identities = 46/138 (33%), Positives = 65/138 (47%), Gaps = 17/138 (12%) Query: 431 QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490 ++ D+ I N SG H + V D+G TCVA N+ G+ L+V K VA Sbjct: 571 RVSGDHAKLIKKNRSGYHR--VCRVRREDAGNYTCVAENEFGKNTASVYLDV--KYPPVA 626 Query: 491 PKFVERFSTLNVREGEPVV-LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549 R +TL+V+EG VV L+ A G P+PR+ W+K G + + + L Sbjct: 627 HV---RPATLSVQEGASVVSLSCDATGNPSPRVQWRKSGSDAVISSQ---------KVLV 674 Query: 550 IPRAKASDAAWYQCTAQN 567 + DA YQCTA N Sbjct: 675 LQNLTRLDAGVYQCTASN 692 Score = 50.0 bits (114), Expect = 5e-05 Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 18/168 (10%) Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG- 472 R + YP VTW+ Y H L + N I VT + GV C N G Sbjct: 730 RCSTEAYPPVTWY-------KIYFHGQLQEVNDNGVYYIRKVTKAHEGVYHCEVSNLIGS 782 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532 +T+ ++V +K P V R + + G+ L +A G P P+ITW P + Sbjct: 783 DTSDLLFVDVKDK-----PAIVSRTTVFLSKVGKAAKLTCQADGYPLPQITWNPS--PPM 835 Query: 533 PNPELRI--HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 N + T A+ + +PR A+D Y+C+A+N G++ +L Sbjct: 836 GNTSYDVIGRTTVRATLIFVPR-NATDFGKYKCSARNENGNSTAIMQL 882 Score = 39.9 bits (89), Expect = 0.049 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 1/75 (1%) Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 G+A + +C+ G PLP + W + S Y + RT TL D G YKC Sbjct: 810 GKAAKLTCQADGYPLPQITWNPSPPMGNTS-YDVIGRTTVRATLIFVPRNATDFGKYKCS 868 Query: 4697 AYNSAGRVTVAAKLK 4711 A N G T +L+ Sbjct: 869 ARNENGNSTAIMQLR 883 Score = 39.1 bits (87), Expect = 0.086 Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 15/117 (12%) Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEG-QPAQ 4739 R+ ED G+Y CVA N G+ T + L V P A PA + V EG Sbjct: 589 RVCRVRREDAGNYTCVAENEFGKNTASVYLDVKYPPVAHVRPA-----TLSVQEGASVVS 643 Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796 T P +QW + G+ D + + VL++ N D G + C A+ Sbjct: 644 LSCDATGNPSPRVQWRKSGS------DAVI---SSQKVLVLQNLTRLDAGVYQCTAS 691 Score = 37.5 bits (83), Expect = 0.26 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 1/60 (1%) Query: 4110 PPVFVSLPDAVTVEEG-EWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFD 4168 PPV P ++V+EG C TG+P PRV W +G+ V S+ L + D Sbjct: 623 PPVAHVRPATLSVQEGASVVSLSCDATGNPSPRVQWRKSGSDAVISSQKVLVLQNLTRLD 682 Score = 37.5 bits (83), Expect = 0.26 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 2/60 (3%) Query: 265 PPKIAQKPRNSKLQEGADA-QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323 PP +P +QEGA +GNP PRV W K+G + S++ +++ N T L Sbjct: 623 PPVAHVRPATLSVQEGASVVSLSCDATGNPSPRVQWRKSGSDAVISSQ-KVLVLQNLTRL 681 Score = 35.5 bits (78), Expect = 1.1 Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 GK + C+ G P P++TW N + ++ ++ + L+ +D G C Sbjct: 810 GKAAKLTCQADGYPLPQITW--NPSPPMGNTSYDVIGRTTVRATLIFVPRNATDFGKYKC 867 Query: 466 VARNKSGET 474 ARN++G + Sbjct: 868 SARNENGNS 876 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/53 (35%), Positives = 25/53 (47%) Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 +P ++G K I + V + DAG YTC A N G+ T S L VK Sbjct: 569 EPRVSGDHAKLIKKNRSGYHRVCRVRREDAGNYTCVAENEFGKNTASVYLDVK 621 Score = 32.7 bits (71), Expect = 7.5 Identities = 16/41 (39%), Positives = 25/41 (60%) Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364 RV ++ D+G+YT +AEN G S YL V+ P ++V+ Sbjct: 589 RVCRVRREDAGNYTCVAENEFGKNTASVYLDVKYPPVAHVR 629 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 9/91 (9%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 P + T T N+ +V+L V + W+K+G D+ N + + L Sbjct: 461 PGTITPTG-NITANQTDVVKLACHVNANPTPAIAWIKDG-----DVTNVLANQS---RLD 511 Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603 ++ Q GKYEC ++N G+ + +V Sbjct: 512 VVVEGKQTEGKYECYSLNLIGQGVAETNLIV 542 Score = 32.3 bits (70), Expect = 9.9 Identities = 41/173 (23%), Positives = 68/173 (39%), Gaps = 29/173 (16%) Query: 403 VTEG-KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461 V EG + C TG P P V W R + ++ S L++ N+T D+G Sbjct: 635 VQEGASVVSLSCDATGNPSPRVQW-------RKSGSDAVI---SSQKVLVLQNLTRLDAG 684 Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT-- 519 V C A N ++ V V + +T+ +R G+ ++ + ++ T Sbjct: 685 VYQCTASN-------GVKIPVTNTSSVTV--IYKPSNTVLLRSGDVILTRSASLRCSTEA 735 Query: 520 -PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 P +TW K I + +L+ D G I + + Y C N+ GS Sbjct: 736 YPPVTWYK----IYFHGQLQEVNDNG--VYYIRKVTKAHEGVYHCEVSNLIGS 782 >SB_14261| Best HMM Match : ig (HMM E-Value=0) Length = 1337 Score = 56.8 bits (131), Expect = 4e-07 Identities = 68/266 (25%), Positives = 119/266 (44%), Gaps = 59/266 (22%) Query: 4438 PLPL-IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496 P+PL I WY++N I L I +V V+D + + GT ++ Sbjct: 555 PVPLQISWYKDNIFI-----------GLGKTLTISKVTVQDEGNYTCNVSSSCGTTLNTS 603 Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556 ++V+ K P + TL+A N G++V+L+ G KP ++ ++ Sbjct: 604 FIIVDYK---------PENTTLSANTTNACVGEMVQLNCSAVG-KPAEITYILK------ 647 Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616 + K++ + G +L+ L + ++ + C+ N+AG + E +++P ++ Sbjct: 648 -MNGKLMSQTGV-SLVRLNSPVVNT--FACIPNNTAGSGQ---EATLNIPVSE------- 693 Query: 4617 KAANAPPEIIE-PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675 PP I++ P K+ I+ EG + E C G P P V WYK L Y +S+ A Sbjct: 694 -----PPSIVQFPSKNIILTEGDSKELMCNASGSPSPAVTWYK---LGIDWVYQNVSKLA 745 Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSA 4701 +S ED G Y+C+A N+A Sbjct: 746 ------LSTR--EDTGSYRCMATNAA 763 Score = 41.1 bits (92), Expect = 0.021 Identities = 64/285 (22%), Positives = 108/285 (37%), Gaps = 53/285 (18%) Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581 N + G V L TG P+ + W K+ I G TL I + QD Sbjct: 537 NGRMVKGSSVTLTCDGTGPVPLQISWYKDN----------IFIGLGK-TLTISKVTVQDE 585 Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641 G Y C +S G + +V KP+ T +AN + G+ ++ Sbjct: 586 GNYTCNVSSSCGTTLNTSFIIVDY-----KPENTTLSANTTNACV----------GEMVQ 630 Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701 +C VGKP K + + MS+T +R++ + C+ N+A Sbjct: 631 LNCSAVGKPAEITYILKMNGKL-------MSQTGVSL-VRLNSPVVNT---FACIPNNTA 679 Query: 4702 GRVTVAA-KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760 G A + V++P P+ ++I++ EG + + P + W + G Sbjct: 680 GSGQEATLNIPVSEPPSIVQFPS----KNIILTEGDSKELMCNASGSPSPAVTWYKLG-- 733 Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805 +++ + + L + EDTG++ C AT AA TS Sbjct: 734 ------IDWVYQNVSKLAL---STREDTGSYRCMATNAAPCKNTS 769 Score = 41.1 bits (92), Expect = 0.021 Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 13/91 (14%) Query: 262 PVS-PPKIAQKP-RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319 PVS PP I Q P +N L EG + SG+P P VTW+K G + N ++ Sbjct: 690 PVSEPPSIVQFPSKNIILTEGDSKELMCNASGSPSPAVTWYKLGIDWVYQNVSKLAL--- 746 Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 + + D+G Y +A N C TS Sbjct: 747 --------STREDTGSYRCMATNAAPCKNTS 769 Score = 38.7 bits (86), Expect = 0.11 Identities = 31/126 (24%), Positives = 61/126 (48%), Gaps = 19/126 (15%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 G+M + +C G+P E+T+ + N K L++++G + + + ++ C Sbjct: 626 GEMVQLNCSAVGKP-AEITYILK-------MNGK-LMSQTGVSLVRLNSPVVN---TFAC 673 Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV--REGEPVVLNARAVGTPTPRIT 523 + N +G + + LN+ E P + +F + N+ EG+ L A G+P+P +T Sbjct: 674 IPNNTAG-SGQEATLNIPVSE----PPSIVQFPSKNIILTEGDSKELMCNASGSPSPAVT 728 Query: 524 WQKDGV 529 W K G+ Sbjct: 729 WYKLGI 734 Score = 35.1 bits (77), Expect = 1.4 Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 19/138 (13%) Query: 437 NHKILVNESGNHALMITNVTLSDSG--VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494 N I N +G +++N+ L+ SG V TCV N+ GE + ++ +V+ V Sbjct: 479 NQTIKTNTNG----VLSNIKLNTSGEHVFTCVPTNEIGEGLN--KTVIVNASEVLPVVSV 532 Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554 + + +G V L G +I+W KD + I G TL I + Sbjct: 533 DIPPNGRMVKGSSVTLTCDGTGPVPLQISWYKDNIFI-----------GLGKTLTISKVT 581 Query: 555 ASDAAWYQCTAQNVAGST 572 D Y C + G+T Sbjct: 582 VQDEGNYTCNVSSSCGTT 599 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 15/82 (18%) Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD-ITHTYE 2840 NI+ EGD+ CN S P P+ T YK D+ Y ++ + + Sbjct: 704 NIILTEGDSKELMCNASGS--------------PSPAVTWYKLGIDWVYQNVSKLALSTR 749 Query: 2841 EDSGIYTCKATNSKGSATTSGS 2862 ED+G Y C ATN+ TS S Sbjct: 750 EDTGSYRCMATNAAPCKNTSFS 771 Score = 32.3 bits (70), Expect = 9.9 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 2/52 (3%) Query: 4110 PPVFVSL-PDAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSRYKL 4159 PP V++ P + TV E + C G P P W+ G+T+ +G Y + Sbjct: 2 PPSSVNITPPSPTVTERDQVNLTCSADGTPPPTFTWIRPQGHTVAHGPSYTI 53 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 15/95 (15%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP-NLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 P+ + + S ++++G +V L T P L+I W+K+ + +G L Sbjct: 178 PVVSVDIPSNSRMIKGSNVTLTCD---GTGPVPLQISWYKDNIFKASGKNL--------- 225 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 +I+ + D G YTC ++ G ++T+ I ++ Sbjct: 226 --TISKVTVQDEGNYTCNVSSSCGTTLNTSFIGVD 258 >SB_15392| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 212 Score = 56.4 bits (130), Expect = 5e-07 Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 7/199 (3%) Query: 4223 QYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQ 4282 Q Q E E ++ E++Q +Q + + E K +V +E + E Q+ K++ EE K+Q Sbjct: 12 QQQNQELEEQQQKEQKQEVQEE---QKQEEQKQEVQEEQKQEVQEEQKQEVQEEQKQKVQ 68 Query: 4283 ELENEQVIKESRLRESTHQYAIPGD--KVTSNTVAKSMAQRYEDNLDQT-EEVTEQRVQK 4339 E + ++V KE + E Q + K K Q+ E +Q EE EQ+ + Sbjct: 69 EEQKQEVQKEQKQEEQEEQKQEVQEEQKQEEQEEQKQEEQKQEVQEEQKQEEQEEQKQEV 128 Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQER 4399 + QK + + + V ++ +++Q Q+E K+ ++ E E E K + QE Sbjct: 129 QEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEEQEEQKQEEQEEQKQEVQE-EQKQEVQEE 187 Query: 4400 VVEGPVKPSKPPIFTKKMQ 4418 + + K + +++Q Sbjct: 188 QKQEVQEEQKQEVQKQEVQ 206 Score = 41.9 bits (94), Expect = 0.012 Identities = 39/178 (21%), Positives = 81/178 (45%), Gaps = 6/178 (3%) Query: 4231 LEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVI 4290 + +T EE+Q Q+Q + K + + E + Q+ K++ EE ++QE + ++V Sbjct: 1 MTRTKEEKQEEQQQNQELEEQQQKEQKQEVQEEQKQEEQKQEVQEEQKQEVQEEQKQEVQ 60 Query: 4291 KE--SRLRESTHQYAIPGDKVTSNTVAKSMA---QRYEDNLDQTEEVTEQRVQKKVTQKP 4345 +E +++E Q K K Q+ E+ +Q +E +Q VQ++ Q+ Sbjct: 61 EEQKQKVQEEQKQEVQKEQKQEEQEEQKQEVQEEQKQEEQEEQKQEEQKQEVQEEQKQEE 120 Query: 4346 RIPDPSESTVHGK-EVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE 4402 + E K EV ++++ Q+E + + +K E + E + + ++ V E Sbjct: 121 QEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEEQEEQKQEEQEEQKQEVQE 178 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/157 (19%), Positives = 75/157 (47%), Gaps = 5/157 (3%) Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYY 4278 +E Q + E + + E++Q +Q++ + + E K +V +E + E Q+ K+++ ++ Sbjct: 53 EEQKQEVQEEQKQKVQEEQKQEVQKEQKQEEQEEQKQEVQEEQKQEEQEEQKQEEQKQEV 112 Query: 4279 NKLQELENE----QVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTE 4334 + Q+ E + Q ++E + +E + + V + Q ++ Q EE E Sbjct: 113 QEEQKQEEQEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEEQEEQKQ-EEQEE 171 Query: 4335 QRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKE 4371 Q+ + + QK + + + V ++ ++++ Q+E Sbjct: 172 QKQEVQEEQKQEVQEEQKQEVQEEQKQEVQKQEVQEE 208 >SB_38293| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1732 Score = 55.6 bits (128), Expect = 9e-07 Identities = 80/344 (23%), Positives = 125/344 (36%), Gaps = 47/344 (13%) Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537 S F V EN GT K +A + + K PS T N+ VT G LV L Sbjct: 461 SVQFTCVPENDVGTGK-NATVTINVK--------AAPSITFITANMTVTEGSLVNLQCNT 511 Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 +G+ P++V W K G +L G+ + QD G Y+C+ +++ E R Sbjct: 512 SGSLPLNVSWSKVGAA-------GVLASSGSQEFSSI-TRAQD-GTYDCM-VHNGDECRA 561 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 ++ V KP+ + N +G + FSC KP Sbjct: 562 ASQRVTI--TVNYKPENCSLTTNT--------SSNTYLKGDDVMFSCHAHSKPSTCNATL 611 Query: 4658 KGDKLIKPSKYFQ-MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716 D S Q S + + + + Y C N AG+ + L + P Sbjct: 612 LHDGTSVTSLTDQTCSGLVTSHVMHNIQGCNAER--YSCRMSNVAGQCEESITLTINDPA 669 Query: 4717 QADNLPALTPLRD-----IVVYEGQPAQFKTQITSKIKPTIQWLREG--ALIPETPDFQM 4769 ++ + TP D I + EG+ T P I W ++G A + ++ Sbjct: 670 SV-HVTSTTPSGDTFASNITIIEGESLTLNCTATGCPTPNITWTKQGVSAALRSNITTEI 728 Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 IH+ I + + D G +TC A G V + + V K Sbjct: 729 IHQ-------IASVQKSDAGRYTCAANNEIGAVSRTLSVTVHYK 765 Score = 53.6 bits (123), Expect = 4e-06 Identities = 38/125 (30%), Positives = 54/125 (43%), Gaps = 12/125 (9%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L I +V D+GV N G+T F+ ++ V+ P V + + V + + Sbjct: 108 LTIKDVQPQDAGVYAMRLANDDGKTTFEASKFTLD---VLVPPGVTPGANVTVNKTDKAE 164 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 L+ A G PTP +TW + G + G TL I K SD Y CTA N Sbjct: 165 LSCSATGNPTPNVTWTRSGGADVL---------GTGETLTISDVKISDGGCYVCTAYNNI 215 Query: 570 GSTAT 574 GS A+ Sbjct: 216 GSEAS 220 Score = 46.4 bits (105), Expect = 6e-04 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557 S + + EGE + LN A G PTP ITW K GV + I + SD Sbjct: 685 SNITIIEGESLTLNCTATGCPTPNITWTKQGVSAALRSNITTEI-----IHQIASVQKSD 739 Query: 558 AAWYQCTAQNVAGSTA 573 A Y C A N G+ + Sbjct: 740 AGRYTCAANNEIGAVS 755 Score = 44.0 bits (99), Expect = 0.003 Identities = 35/115 (30%), Positives = 47/115 (40%), Gaps = 12/115 (10%) Query: 3121 YSCRATNKWGQAEISVKLECVDKSK----GQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176 YSCR +N GQ E S+ L D + P T NI + +G+S CT Sbjct: 646 YSCRMSNVAGQCEESITLTINDPASVHVTSTTPSGDTFASNIT-IIEGESLTLNCTATGC 704 Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 P+ I W G + I T ++ IA Q D+G Y C A N+ G Sbjct: 705 PTPN--ITWTKQGVSAALRSNITTE-----IIHQIASVQKSDAGRYTCAANNEIG 752 Score = 40.3 bits (90), Expect = 0.037 Identities = 67/286 (23%), Positives = 98/286 (34%), Gaps = 44/286 (15%) Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP----DIRNKILEEDGTY---TLLILEA 4576 N+T + + K +++ +L +G P D +++ T+ TL I + Sbjct: 54 NITPPATISVRVANIDVKGVNIGFLADGSPPMPIVYTDFKSRYSLSTATFNPITLTIKDV 113 Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636 PQD+G Y N G+ +A T PP + P + V + Sbjct: 114 QPQDAGVYAMRLANDDGKTTFEASKF-------------TLDVLVPPGVT-PGANVTVNK 159 Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 E SC G P P V W + S + T + TL IS+ D G Y C Sbjct: 160 TDKAELSCSATGNPTPNVTWTR-------SGGADVLGTGE--TLTISDVKISDGGCYVCT 210 Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI--QW 4754 AYN+ G Q A N A + +V +G P I + Sbjct: 211 AYNNIGSEASGTVCLTVQ--YAPN--ATISVNTTLVCQGDHVALTCTAGDSFPPVIGYHF 266 Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 R G LI + NN +T + FTC A AG Sbjct: 267 YRGGTLI--------VTSSNNEYTAAASTGLPEFNEFTCAAYNLAG 304 Score = 39.9 bits (89), Expect = 0.049 Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 7/87 (8%) Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763 NI + EG + +C G PT I W G A S + T I I + Sbjct: 686 NITIIEGESLTLNCTA--TGCPTPNITWTKQGVSAALRSNITTE-----IIHQIASVQKS 738 Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAK 3790 DAG YTC A N+ G+ + T +T K Sbjct: 739 DAGRYTCAANNEIGAVSRTLSVTVHYK 765 Score = 39.1 bits (87), Expect = 0.086 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 5/74 (6%) Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333 N + EG +G P P +TW K G +++ ITT ++ + QKSD+ Sbjct: 686 NITIIEGESLTLNCTATGCPTPNITWTKQG---VSAALRSNITTE--IIHQIASVQKSDA 740 Query: 334 GHYTLLAENPNGCI 347 G YT A N G + Sbjct: 741 GRYTCAANNEIGAV 754 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 7/81 (8%) Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713 ++EG+ + L PN I W K GV+ A L+S ++ I S++ D+G Sbjct: 689 IIEGESLTLNCTATGCPTPN--ITWTKQGVS----AALRSNITTEIIH-QIASVQKSDAG 741 Query: 2714 IYTCKATNLLGEAVSTASIKI 2734 YTC A N +G T S+ + Sbjct: 742 RYTCAANNEIGAVSRTLSVTV 762 Score = 37.9 bits (84), Expect = 0.20 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 5/65 (7%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G T + W K G S ITT + I SV DAG YTC A N IG + + Sbjct: 703 GCPTPNITWTKQGVSAALRSNITT-----EIIHQIASVQKSDAGRYTCAANNEIGAVSRT 757 Query: 997 ANLTI 1001 ++T+ Sbjct: 758 LSVTV 762 Score = 37.5 bits (83), Expect = 0.26 Identities = 16/38 (42%), Positives = 21/38 (55%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551 PS T N+ VT G LV L +G+ P++V W K G Sbjct: 1024 PSITFITANMTVTEGSLVNLQCNTSGSPPLNVSWSKVG 1061 Score = 37.1 bits (82), Expect = 0.35 Identities = 34/132 (25%), Positives = 52/132 (39%), Gaps = 15/132 (11%) Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495 Y + +V+ES + + + TL+ TCV N G T +++ P+ Sbjct: 1577 YRNDDVVDESAT-GMFVISPTLAGDNAYTCVPNNTLG-TGQNSSVHITT---TAPPRIHG 1631 Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555 S L V EG V L A G+ +TW+ PN TL++ Sbjct: 1632 ITSDLTVTEGSDVALQCNATGSEPLNVTWRS------PNGAFL----SSGVTLNLNILSR 1681 Query: 556 SDAAWYQCTAQN 567 +D YQC+A N Sbjct: 1682 NDEGSYQCSASN 1693 Score = 36.7 bits (81), Expect = 0.46 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 11/151 (7%) Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441 +I + +K A QF D +G+ C + +P F + I +Y Sbjct: 1189 QIAVKDKPEATQFSLNTSDGAYLKGEPVSLYCNSSAKPALCHVVFRKNDVIIKNYTSDTC 1248 Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSG---ETAFQCRLN---VIEKEQVVAPKFVE 495 S +H +I++V D +C A N +G E + + I P+ + Sbjct: 1249 ---SASH--LISSVEGCDRESFSCQAFNIAGTGDEVFYNATIQDAPAIISVMSQTPQGPK 1303 Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQK 526 S++ + EGE + LN A G P P ITW K Sbjct: 1304 AASSIALLEGETLTLNCTASGCPAPNITWYK 1334 Score = 36.3 bits (80), Expect = 0.61 Identities = 16/38 (42%), Positives = 21/38 (55%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551 PS T N+ VT G LV L +G+ P++V W K G Sbjct: 852 PSITFINANMTVTEGSLVNLQCNTSGSLPLNVSWSKVG 889 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 6/70 (8%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 + EG+ +C TG P P +TW + + + N + I +V SD+G Sbjct: 689 IIEGESLTLNCTATGCPTPNITW------TKQGVSAALRSNITTEIIHQIASVQKSDAGR 742 Query: 463 VTCVARNKSG 472 TC A N+ G Sbjct: 743 YTCAANNEIG 752 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 6/81 (7%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P + W + GV + +TT + + V D+G YTC A NE+G + Sbjct: 703 GCPTPNITWTKQGVSAALRSNITTE-----IIHQIASVQKSDAGRYTCAANNEIGAVSRT 757 Query: 1798 STLFVQSK-ASLQLESQHESA 1817 ++ V K + QL S SA Sbjct: 758 LSVTVHYKPINTQLTSTKTSA 778 Score = 33.9 bits (74), Expect = 3.2 Identities = 16/41 (39%), Positives = 21/41 (51%) Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 VTV + + A C TG+P P V W +G V G+ LT Sbjct: 155 VTVNKTDKAELSCSATGNPTPNVTWTRSGGADVLGTGETLT 195 Score = 33.1 bits (72), Expect = 5.7 Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 7/82 (8%) Query: 72 PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131 P + N +G + G PTP ++WT++ ++R N T ++ Sbjct: 678 PSGDTFASNITIIEGESLTLNCTATGCPTPNITWTKQGVSA------ALRSNITT-EIIH 730 Query: 132 LIKQIGPGDEGEYTCTARNQYG 153 I + D G YTC A N+ G Sbjct: 731 QIASVQKSDAGRYTCAANNEIG 752 Score = 32.7 bits (71), Expect = 7.5 Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 969 LTIKSVTVHDAGHYTCRAYNAIG-QATTSANLTI 1001 LTI V + D G Y C AYN IG +A+ + LT+ Sbjct: 194 LTISDVKISDGGCYVCTAYNNIGSEASGTVCLTV 227 Score = 32.7 bits (71), Expect = 7.5 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 9/88 (10%) Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704 ++T +EG + G PT I W K G S S T+ I + S+ Sbjct: 686 NITIIEGESLTLNCTA--TGCPTPNITWTKQGVSAALRSNITT-----EIIHQIASVQKS 738 Query: 705 DSGEYTCRAVSATG-VAETKAV-LHVTP 730 D+G YTC A + G V+ T +V +H P Sbjct: 739 DAGRYTCAANNEIGAVSRTLSVTVHYKP 766 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 5/68 (7%) Query: 795 TPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEA 854 T PT + W K G S IT+ + I ++ DAG YT A N++G Sbjct: 700 TATGCPTPNITWTKQGVSAALRSNITT-----EIIHQIASVQKSDAGRYTCAANNEIGAV 754 Query: 855 ISTASIRV 862 T S+ V Sbjct: 755 SRTLSVTV 762 Score = 32.7 bits (71), Expect = 7.5 Identities = 14/45 (31%), Positives = 22/45 (48%) Query: 385 ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIND 429 IS + PQ K + EG+ +C +G P P +TW+ +D Sbjct: 1292 ISVMSQTPQGPKAASSIALLEGETLTLNCTASGCPAPNITWYKHD 1336 Score = 32.3 bits (70), Expect = 9.9 Identities = 30/111 (27%), Positives = 44/111 (39%), Gaps = 12/111 (10%) Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675 T A PP I + VAEG + C G P + I+ + Q+S T Sbjct: 312 TVQAKVPPAITGFSPPQNVAEGSEVMLECNATGSS-PNIT-------IERNGEAQLSTTG 363 Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP 4726 IS +EG Y+C+ +N TV + +T + +N LTP Sbjct: 364 KHTFAAISR---REEGSYRCIVHNGGECPTVYSTTNITVNYKPEN-TTLTP 410 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 7/84 (8%) Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378 NI +EG ++ L C G T + W G + R E + + SV Sbjct: 686 NITIIEGESLTLNCTA--TGCPTPNITWTKQG--VSAALRSNITTEIIH---QIASVQKS 738 Query: 1379 DSGVYTCQATNQLGEAVTSCALRV 1402 D+G YTC A N++G + ++ V Sbjct: 739 DAGRYTCAANNEIGAVSRTLSVTV 762 >SB_29770| Best HMM Match : ig (HMM E-Value=3.4e-05) Length = 454 Score = 54.8 bits (126), Expect = 2e-06 Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 10/167 (5%) Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464 EG T C+VTG+ + T + D N + + H ++I +V +D+G+ Sbjct: 250 EGSRTNISCQVTGQAFIMWTTPLGHSVPYDRTNRLYVFSNGFRHDVIIESVNRTDAGLYR 309 Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524 C S RL V +++ + + + N + +P+ LN G P P + Sbjct: 310 CYGNTDSKAV----RLEVEYAPELIQSESTTQVTWSNYADRDPIELNCTFDGFPVPTVEL 365 Query: 525 QKDGVPIIPNPELRIHTDGGASTLDIPRAKASD-AAWYQCTAQNVAG 570 KD I + T G S + RAK+ + +YQCTA+N G Sbjct: 366 YKDSKVITSHV-----TKGRGSLVYKARAKSIEYYGFYQCTARNTQG 407 Score = 39.9 bits (89), Expect = 0.049 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694 A+ IE +C G P+PTV+ YK K+I + + R + Y R E G Y+ Sbjct: 344 ADRDPIELNCTFDGFPVPTVELYKDSKVI--TSHVTKGRGSLVYKARAKSI--EYYGFYQ 399 Query: 4695 CVAYNSAGRVT 4705 C A N+ G VT Sbjct: 400 CTARNTQGEVT 410 >SB_54662| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 673 Score = 54.8 bits (126), Expect = 2e-06 Identities = 47/168 (27%), Positives = 63/168 (37%), Gaps = 8/168 (4%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 G T C + G P P + W +QI H ++G L+I D G C Sbjct: 112 GWETTLTCDIFGFPPPHIEWTRALQQI-----HSGRTRQAGRR-LIIKKTEQQDRGPYMC 165 Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525 NK G L V K T+ R G + L A G+PTP I W Sbjct: 166 TGTNKLGSVFALIVLTVYPVVPPTITKSPPPVVTVQ-RRGATLQLTCAAQGSPTPTIEWS 224 Query: 526 KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 KDG +I + R + +L +P + D YQC +N TA Sbjct: 225 KDG-RLISTNDSRSEANTREGSLVMPYFQPEDQGDYQCFFRNFDNGTA 271 Score = 51.6 bits (118), Expect = 2e-05 Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 13/129 (10%) Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 L+I + QD G Y C N G ++ L P TK+ PP ++ Sbjct: 150 LIIKKTEQQDRGPYMCTGTNKLGSVFA----LIVLTVYPVVPPTITKS---PPPVVT--- 199 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 + G ++ +C G P PT++W K +LI + + T E +L + PED+ Sbjct: 200 --VQRRGATLQLTCAAQGSPTPTIEWSKDGRLISTNDSRSEANTR-EGSLVMPYFQPEDQ 256 Query: 4691 GDYKCVAYN 4699 GDY+C N Sbjct: 257 GDYQCFFRN 265 Score = 45.6 bits (103), Expect = 0.001 Identities = 40/157 (25%), Positives = 56/157 (35%), Gaps = 7/157 (4%) Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 G +C I G P P ++W + + I + Q R L I + +D G Y C Sbjct: 112 GWETTLTCDIFGFPPPHIEWTRALQQIHSGRTRQAGR-----RLIIKKTEQQDRGPYMCT 166 Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756 N G V L V P + P V G Q PTI+W + Sbjct: 167 GTNKLGSVFALIVLTV-YPVVPPTITKSPPPVVTVQRRGATLQLTCAAQGSPTPTIEWSK 225 Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793 +G LI T D + L++ ED G + C Sbjct: 226 DGRLI-STNDSRSEANTREGSLVMPYFQPEDQGDYQC 261 Score = 38.7 bits (86), Expect = 0.11 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 3/83 (3%) Query: 262 PVSPPKIAQKPRN--SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319 PV PP I + P + + GA Q G+P P + W K+G RLI++N Sbjct: 184 PVVPPTITKSPPPVVTVQRRGATLQLTCAAQGSPTPTIEWSKDG-RLISTNDSRSEANTR 242 Query: 320 HTTLRVRNTQKSDSGHYTLLAEN 342 +L + Q D G Y N Sbjct: 243 EGSLVMPYFQPEDQGDYQCFFRN 265 Score = 38.7 bits (86), Expect = 0.11 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G + +G+PTP + W+ K L+ N N + G SL++ P D+G+Y Sbjct: 203 RGATLQLTCAAQGSPTPTIEWS-KDGRLISTNDSRSEANTREG--SLVMPYFQPEDQGDY 259 Query: 145 TCTARN 150 C RN Sbjct: 260 QCFFRN 265 Score = 34.3 bits (75), Expect = 2.5 Identities = 54/216 (25%), Positives = 74/216 (34%), Gaps = 27/216 (12%) Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL--DIPRAKAS 556 TL ++G+ + + A G P P I W DG P P P G +TL DI Sbjct: 70 TLVAKQGQNLKIPCIATGFPEPVIAWSHDGKP--PPPVYLPGYIGWETTLTCDIFGFPPP 127 Query: 557 DAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLR 616 W + Q +G T R + ++ T Y Sbjct: 128 HIEWTRALQQIHSGRTRQAGR--RLIIKKTEQQDRGPYMCTGTNKLGSVFALIVLTVY-- 183 Query: 617 HVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG 676 P +PP PPP V + T + G PT IEW K+G Sbjct: 184 ------PVVPPTITKS--PPPVVTVQRRGAT--------LQLTCAAQGSPTPTIEWSKDG 227 Query: 677 QSIEAS-SRFTSIFRFGYISLDMLSLNIQDSGEYTC 711 + I + SR + R G SL M +D G+Y C Sbjct: 228 RLISTNDSRSEANTREG--SLVMPYFQPEDQGDYQC 261 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/71 (35%), Positives = 30/71 (42%), Gaps = 7/71 (9%) Query: 2131 CRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKL 2190 C + PH I+W Q+I +G T G L I T +D G YMC TNKL Sbjct: 119 CDIFGFPPPH--IEWTRALQQIHSGR----TRQAGR-RLIIKKTEQQDRGPYMCTGTNKL 171 Query: 2191 GEAVNTCTLKV 2201 G L V Sbjct: 172 GSVFALIVLTV 182 Score = 32.3 bits (70), Expect = 9.9 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 14/109 (12%) Query: 54 SSGDRQPITA-GRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL 112 ++G +P+ A G+P PP++ + G + G P P + WTR + Sbjct: 85 ATGFPEPVIAWSHDGKPPPPVYLPGYI------GWETTLTCDIFGFPPPHIEWTRALQQI 138 Query: 113 VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161 +S R Q G L+IK+ D G Y CT N+ G + + Sbjct: 139 -----HSGR-TRQAGR-RLIIKKTEQQDRGPYMCTGTNKLGSVFALIVL 180 Score = 32.3 bits (70), Expect = 9.9 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 13/89 (14%) Query: 2365 PEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI--EDS 2422 P +P +T+ P P+ + + G T C G PT +EW ++ +LI DS Sbjct: 184 PVVPPTITKSPP----PVVTVQ--RRGATLQLTCAA--QGSPTPTIEWSKDGRLISTNDS 235 Query: 2423 SRITKTHDFGYVSMTISHVRDEDEGVYMC 2451 T + S+ + + + ED+G Y C Sbjct: 236 RSEANTRE---GSLVMPYFQPEDQGDYQC 261 >SB_29852| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 836 Score = 54.4 bits (125), Expect = 2e-06 Identities = 54/230 (23%), Positives = 92/230 (40%), Gaps = 21/230 (9%) Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640 +GKY+C A +++G R D ++ ++ P + + AP E K+ +V + Sbjct: 311 AGKYKCKATDTSG--RTDTS--TTIVRMEETPAGFGQGSRAP----EASKNALV--DSTV 360 Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700 C+ G P P V+W KG + +Q + D L+IS D G Y C N Sbjct: 361 TLHCQPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNR 417 Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK--IKPTIQWLREG 4758 G + +L V D + P + + G +F +T+ + QW R Sbjct: 418 LGSASRTGRLNV-----QDKIAVTHPPDNKIATVGGTVRFTCGVTTSGVTEVVFQWRRFV 472 Query: 4759 ALIPETPDFQMIHEGNNAVLL-IGNTYEEDTGTFTCRATTAAGQVETSAK 4807 L+ + M G L I D G + C+AT + + + S++ Sbjct: 473 FLLQPSSRISMGKIGEQTGFLEIRGVEFSDQGLYACKATGSIQKDDASSE 522 Score = 51.6 bits (118), Expect = 2e-05 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 17/229 (7%) Query: 356 ESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTE----GKMTRF 411 +S + YV + I Q R + + + L PQ KV + VT+ G+ Sbjct: 210 QSDSGDYVCTVTNNNINKQQVRTVVLNV-MPVRPLIPQPPKVSTEFSVTKIALKGERFVL 268 Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNK 470 +C V G P P++T +R H IL +GN I T + +G C A + Sbjct: 269 ECIVYGMPVPKIT-------LRKKGVHMILGQVTGNARRHYIPKFTANHAGKYKCKATDT 321 Query: 471 SGETAFQCRLNVIEKEQVVAPKFVER-FSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529 SG T + +E+ + ++ N V L+ + G P P + W+K V Sbjct: 322 SGRTDTSTTIVRMEETPAGFGQGSRAPEASKNALVDSTVTLHCQPSGNPKPMVRWRKGSV 381 Query: 530 PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + P + T G L I + D+ Y C N GS + RL Sbjct: 382 YLSSGPRYQFLTSG---DLKISNVTSLDSGRYTCEVSNRLGSASRTGRL 427 Score = 48.4 bits (110), Expect = 1e-04 Identities = 54/239 (22%), Positives = 93/239 (38%), Gaps = 23/239 (9%) Query: 4580 DSGKYEC-VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638 DSG Y C V N+ + + + +P P+P P E KI +G+ Sbjct: 212 DSGDYVCTVTNNNINKQQVRTVVLNVMPVRPLIPQP-------PKVSTEFSVTKIALKGE 264 Query: 4639 AIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697 C + G P+P + K G +I Q++ A + I + G YKC A Sbjct: 265 RFVLECIVYGMPVPKITLRKKGVHMILG----QVTGNARRHY--IPKFTANHAGKYKCKA 318 Query: 4698 YNSAGRV---TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754 +++GR T +++ T A ++ +V Q + KP ++W Sbjct: 319 TDTSGRTDTSTTIVRMEETPAGFGQGSRAPEASKNALV--DSTVTLHCQPSGNPKPMVRW 376 Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 + + P +Q + G+ L I N D+G +TC + G + +L V+ K Sbjct: 377 RKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSASRTGRLNVQDK 432 Score = 48.4 bits (110), Expect = 1e-04 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 7/85 (8%) Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYR--TSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926 +P +P V W L SG RY+ TS D L I V DSG YTC+ N LG Sbjct: 365 QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD-----LKISNVTSLDSGRYTCEVSNRLG 419 Query: 1927 QAVSSIRLNVQSKESIIRDSQHESA 1951 A + RLNVQ K ++ ++ A Sbjct: 420 SASRTGRLNVQDKIAVTHPPDNKIA 444 Score = 44.8 bits (101), Expect = 0.002 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 2667 EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726 +P +P + W K V L++G R + L ++ SL DSG YTC+ +N LG A Sbjct: 365 QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGDLKISNVTSL---DSGRYTCEVSNRLGSA 421 Query: 2727 VSTASIKIEDR 2737 T + ++D+ Sbjct: 422 SRTGRLNVQDK 432 Score = 42.3 bits (95), Expect = 0.009 Identities = 50/192 (26%), Positives = 77/192 (40%), Gaps = 22/192 (11%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495 G P P+++W + + + + P +Q F T L I V DS + NR G+A + Sbjct: 368 GNPKPMVRWRKGSVYLSSGPRYQ---FLTSGDLKISNVTSLDSGRYTCEVSNRLGSASRT 424 Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT--GTKPIDVYWLKNGKK 4553 L V++K + T N T G VR VT G + W + Sbjct: 425 GRLNVQDK----------IAVTHPPDNKIATVGGTVRFTCGVTTSGVTEVVFQWRRFVFL 474 Query: 4554 VQPDIR---NKILEEDGTYTLLILEAYPQDSGKYECVAINS--AGEARCDAECVVSLPAT 4608 +QP R KI E+ G + +E D G Y C A S +A +A ++++ Sbjct: 475 LQPSSRISMGKIGEQTGFLEIRGVEF--SDQGLYACKATGSIQKDDASSEAFALLNVQGA 532 Query: 4609 KDKPKPQTKAAN 4620 +KP T N Sbjct: 533 PEKPHGVTILPN 544 Score = 41.9 bits (94), Expect = 0.012 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 4/79 (5%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C+ +G P P V W + ++ L SG+ L I+NVT DSG TC N+ G Sbjct: 364 CQPSGNPKPMVRWRKGSVYLSSGPRYQFLT--SGD--LKISNVTSLDSGRYTCEVSNRLG 419 Query: 473 ETAFQCRLNVIEKEQVVAP 491 + RLNV +K V P Sbjct: 420 SASRTGRLNVQDKIAVTHP 438 Score = 41.9 bits (94), Expect = 0.012 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347 Q SGNP+P V W K L + +++ +T+ + L++ N DSG YT N G Sbjct: 365 QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSA 421 Query: 348 VTSGYLAVE 356 +G L V+ Sbjct: 422 SRTGRLNVQ 430 Score = 40.3 bits (90), Expect = 0.037 Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 14/163 (8%) Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133 P+G+ ++ W + + R + + + L+I + DSG Y+C +N+ G A Sbjct: 366 PSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSAS 422 Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193 + +L DK TH + + G + F C V ++ +W ++ Sbjct: 423 RTGRLNVQDKIA------VTHPPDNKIATVGGTVRFTCGVTTSGVTEVVFQWRRFVFLLQ 476 Query: 3194 HSTRI---KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233 S+RI K GF L+I + D G Y C+A +D Sbjct: 477 PSSRISMGKIGEQTGF--LEIRGVEFSDQGLYACKATGSIQKD 517 Score = 39.9 bits (89), Expect = 0.049 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Query: 2798 EPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSA 2857 +PS +P + W + L SG RY+ + L I++ DSG YTC+ +N GSA Sbjct: 365 QPSGNPKPMVRWRKGSVYLSSGPRYQF---LTSGDLKISNVTSLDSGRYTCEVSNRLGSA 421 Query: 2858 TTSGSL 2863 + +G L Sbjct: 422 SRTGRL 427 Score = 39.9 bits (89), Expect = 0.049 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 3/73 (4%) Query: 1736 PVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795 P G+PK V W + V + + R + L + V DSG YTC N LG A Sbjct: 366 PSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSAS 422 Query: 1796 TSSTLFVQSKASL 1808 + L VQ K ++ Sbjct: 423 RTGRLNVQDKIAV 435 Score = 37.9 bits (84), Expect = 0.20 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%) Query: 3720 EPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779 +P G+P + W ++G R L L I + + D+G YTC +N+ GSA Sbjct: 365 QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSA 421 Query: 3780 TTTAKITCSAK 3790 + T ++ K Sbjct: 422 SRTGRLNVQDK 432 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254 + L C +P G+P V W ++ G R++ + G L I + TS D+G YT Sbjct: 360 VTLHC--QPSGNPKPMVRWRKGSVYLSSGPRYQ-FLTSG--DLKISNVTSLDSGRYTCEV 414 Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQA 1284 N LGSA + + V ++ + N+ A Sbjct: 415 SNRLGSASRTGRLNVQDKIAVTHPPDNKIA 444 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%) Query: 3446 PTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505 P+ +P V W L +G R++ F G L+IS DSG Y C N G A Sbjct: 366 PSGNPKPMVRWRKGSVYLSSGPRYQ-FLTSGD--LKISNVTSLDSGRYTCEVSNRLGSAS 422 Query: 3506 TTASMKVQGK 3515 T + VQ K Sbjct: 423 RTGRLNVQDK 432 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 5/87 (5%) Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678 + + P+II KD +V G + C + TV WY I M ++ D Sbjct: 46 STSKPQIIVGPKDTLV-HGTSFTLMC--IATKDSTVTWYHDGNRIDFQWQTNMQQSKDG- 101 Query: 4679 TLRISEAFPE-DEGDYKCVAYNSAGRV 4704 +L +S A D+G Y+CV NS G + Sbjct: 102 SLHVSNAISSRDKGPYRCVVSNSRGTI 128 Score = 35.5 bits (78), Expect = 1.1 Identities = 39/165 (23%), Positives = 66/165 (40%), Gaps = 16/165 (9%) Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130 +L+ + + W+++G I+ + + + + D G Y C +N G Sbjct: 67 TLMCIATKDSTVTWYHDGNRIDFQWQTNMQQSKDGSLHVSNAISSRDKGPYRCVVSNSRG 126 Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG- 3189 IS + K P T+ + G ++ SA C P PD +I+W Sbjct: 127 TI-ISRRANV--KFPYLMPFAVTNF--VIGKEESHSAVLHCQA-PDSYPDRQIQWSKQDP 180 Query: 3190 ------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228 +P+ S++ T+S G L AY + DSG+YVC N Sbjct: 181 NFPGRRRPLPQSSKY-TISSEGD--LHFAYLEQSDSGDYVCTVTN 222 Score = 35.5 bits (78), Expect = 1.1 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 10/82 (12%) Query: 2916 PIAAEHQLVEGQV-LHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK-LTSDFGFVTLDL 2973 P A+++ LV+ V LH + P +P + W L G R++ LTS L + Sbjct: 348 PEASKNALVDSTVTLHCQ----PSGNPKPMVRWRKGSVYLSSGPRYQFLTSG----DLKI 399 Query: 2974 VDVYERDSGIYTCKAYNKRGEA 2995 +V DSG YTC+ N+ G A Sbjct: 400 SNVTSLDSGRYTCEVSNRLGSA 421 Score = 35.5 bits (78), Expect = 1.1 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 1326 TNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTC 1385 + V L C QP G+ V W + +G R++ D L + +V DSG YTC Sbjct: 358 STVTLHC--QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTC 412 Query: 1386 QATNQLGEAVTSCALRV 1402 + +N+LG A + L V Sbjct: 413 EVSNRLGSASRTGRLNV 429 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 934 EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993 +P G+ V W K + + R F G L I +VT D+G YTC N +G A Sbjct: 365 QPSGNPKPMVRWRKGSVYLSSGPRYQ-FLTSG--DLKISNVTSLDSGRYTCEVSNRLGSA 421 Query: 994 TTSANLTIVTK 1004 + + L + K Sbjct: 422 SRTGRLNVQDK 432 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%) Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631 +S+ C+ P + V W L +G R + + L+I V D+G YT Sbjct: 357 DSTVTLHCQ--PSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYT 411 Query: 3632 CKATNRHGEATVSCKLQVKGRQGIILEP 3659 C+ +NR G A+ + +L V+ + + P Sbjct: 412 CEVSNRLGSASRTGRLNVQDKIAVTHPP 439 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 5/59 (8%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155 GNP P+V W + L +Y +GD L I + D G YTC N+ G A Sbjct: 368 GNPKPMVRWRKGSVYLSSGPRYQFL---TSGD--LKISNVTSLDSGRYTCEVSNRLGSA 421 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 3/58 (5%) Query: 3854 EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 +P +PK + W + L SG RY+ + L I V + DSG Y C N G Sbjct: 365 QPSGNPKPMVRWRKGSVYLSSGPRYQFLTS---GDLKISNVTSLDSGRYTCEVSNRLG 419 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 7/70 (10%) Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYR--TTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191 +P +P + W + +G RY+ T+ D L I + DSG Y C+ +N+LG Sbjct: 365 QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD-----LKISNVTSLDSGRYTCEVSNRLG 419 Query: 2192 EAVNTCTLKV 2201 A T L V Sbjct: 420 SASRTGRLNV 429 >SB_16673| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 529 Score = 54.4 bits (125), Expect = 2e-06 Identities = 53/202 (26%), Positives = 81/202 (40%), Gaps = 26/202 (12%) Query: 389 ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448 +L Q+V V + + K +CR TG P P++ W + ++ D K+ N Sbjct: 129 SLQKQYVLV---QSIKSPKDLIINCRATGYPTPQIIWTRYNGKLSADRTRKM-----PNG 180 Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508 L+I+ T D G +C+ N+ G ++V+E PK + + + + GE Sbjct: 181 TLVISKATRGDGGAYSCLVTNELGRDLKNFTVSVLEP-----PKILGK-TEFHFNVGETA 234 Query: 509 VLNARAVGTPTPRITWQ-----------KDGVPIIPNPELRIHTDGGA-STLDIPRAKAS 556 L ++ G P P +TW KDG TD STL I A Sbjct: 235 KLFCKSRGNPPPAVTWSWKDIDNKTVILKDGEDDSRRRVAITDTDDFVVSTLTIDSVTAD 294 Query: 557 DAAWYQCTAQNVAGSTATRARL 578 D Y+C A+N G A L Sbjct: 295 DWKTYRCIAKNKFGDDAENIAL 316 Score = 41.1 bits (92), Expect = 0.021 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 9/81 (11%) Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN------KPLP-SGTRY--KSTHDF 2828 S L N+ KEG++ C + P +P I WF N + +P S T+Y ++ Sbjct: 21 SELQNVTVKEGEDAILPCALPPRVEPKYLITWFMGNAKYLTKRMMPTSTTKYIDRAMEID 80 Query: 2829 SYVSLDITHTYEEDSGIYTCK 2849 S +L + T ED+G Y+CK Sbjct: 81 SQDALVLRKTVREDTGTYSCK 101 Score = 40.3 bits (90), Expect = 0.037 Identities = 38/185 (20%), Positives = 78/185 (42%), Gaps = 17/185 (9%) Query: 399 QDRDVTEGKMTRFDCRVTGRPYPE--VTWFIND-----RQIRDDYNHKIL---VNESGNH 448 Q+ V EG+ C + R P+ +TWF+ + +++ K + + Sbjct: 24 QNVTVKEGEDAILPCALPPRVEPKYLITWFMGNAKYLTKRMMPTSTTKYIDRAMEIDSQD 83 Query: 449 ALMITNVTLSDSGVVTC--VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL-NVREG 505 AL++ D+G +C + S +TA + ++ V+ +++ + +++ Sbjct: 84 ALVLRKTVREDTGTYSCKVLYYGPSMQTAAAQIMLFVKGPPVITSSLQKQYVLVQSIKSP 143 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 + +++N RA G PTP+I W + + + ++ TL I +A D Y C Sbjct: 144 KDLIINCRATGYPTPQIIWTRYNGKLSADRTRKMPN----GTLVISKATRGDGGAYSCLV 199 Query: 566 QNVAG 570 N G Sbjct: 200 TNELG 204 Score = 38.3 bits (85), Expect = 0.15 Identities = 68/288 (23%), Positives = 108/288 (37%), Gaps = 46/288 (15%) Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496 EP LI W+ N K + T +TK I ++ +D+ V GT C Sbjct: 45 EPKYLITWFMGN--AKYLTKRMMPTSTTKYIDRAMEIDSQDALVLRKTVREDTGTYSCKV 102 Query: 4497 NLVVEEKRRQGRGGIV-----PPSFTLTAQNV-----NVTSGQLVRLDTKVTGTKPIDVY 4546 L + I+ PP T + Q ++ S + + ++ + TG + Sbjct: 103 -LYYGPSMQTAAAQIMLFVKGPPVITSSLQKQYVLVQSIKSPKDLIINCRATGYPTPQII 161 Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606 W + K+ D K+ +GT L+I +A D G Y C+ N G Sbjct: 162 WTRYNGKLSADRTRKM--PNGT--LVISKATRGDGGAYSCLVTNELG------------- 204 Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD-----K 4661 +D K T + PP+I+ + G+ + CK G P P V W D Sbjct: 205 --RDL-KNFTVSVLEPPKILGKTEFHFNV-GETAKLFCKSRGNPPPAVTWSWKDIDNKTV 260 Query: 4662 LIKPSKYFQMSRTA----DEY---TLRISEAFPEDEGDYKCVAYNSAG 4702 ++K + R A D++ TL I +D Y+C+A N G Sbjct: 261 ILKDGEDDSRRRVAITDTDDFVVSTLTIDSVTADDWKTYRCIAKNKFG 308 Score = 33.1 bits (72), Expect = 5.7 Identities = 46/196 (23%), Positives = 75/196 (38%), Gaps = 21/196 (10%) Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFY-NGK--------TIEASHRIRTVYAFGMVVL 3108 V + EG+ A +L P + +I WF N K T + R + L Sbjct: 26 VTVKEGEDAILPCALPPRVEPKYLITWFMGNAKYLTKRMMPTSTTKYIDRAMEIDSQDAL 85 Query: 3109 EILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQN----IEGLKDG 3164 + T D+GTYSC+ +G + + + + KG P T+ +Q ++ +K Sbjct: 86 VLRKTVREDTGTYSCKVLY-YGPSMQTAAAQIMLFVKGP-PVITSSLQKQYVLVQSIKSP 143 Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 + C P + I +NG+ TR K + L I+ D G Y C Sbjct: 144 KDLIINCRATGYPTPQI-IWTRYNGKLSADRTR-KMPNG----TLVISKATRGDGGAYSC 197 Query: 3225 RAYNKYGEDFTRATIN 3240 N+ G D T++ Sbjct: 198 LVTNELGRDLKNFTVS 213 Score = 32.7 bits (71), Expect = 7.5 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 10/82 (12%) Query: 83 FAQGGNAKFEGKLRGNPTPVVSWTRK----KAPLVECNKYSMRYNEQTGDV------SLL 132 F G AK K RGNP P V+W+ K K +++ + R D +L Sbjct: 228 FNVGETAKLFCKSRGNPPPAVTWSWKDIDNKTVILKDGEDDSRRRVAITDTDDFVVSTLT 287 Query: 133 IKQIGPGDEGEYTCTARNQYGE 154 I + D Y C A+N++G+ Sbjct: 288 IDSVTADDWKTYRCIAKNKFGD 309 Score = 32.3 bits (70), Expect = 9.9 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 9/84 (10%) Query: 1581 TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNN-KPLKSGSRFTETNNFGFVALDI 1639 ++ L+NV +KEG+ A L P + + W+ N K L T T + A++I Sbjct: 20 SSELQNVTVKEGEDAILPCALPPRVEPKYLITWFMGNAKYLTKRMMPTSTTKYIDRAMEI 79 Query: 1640 MS--------CLPEDSGTYTCRAI 1655 S + ED+GTY+C+ + Sbjct: 80 DSQDALVLRKTVREDTGTYSCKVL 103 Score = 32.3 bits (70), Expect = 9.9 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 11/75 (14%) Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV----------ALD 2170 +KEG+ A C + P +P I WF K R T Y+ AL Sbjct: 28 VKEGEDAILPCALPPRVEPKYLITWFMGNAKYLT-KRMMPTSTTKYIDRAMEIDSQDALV 86 Query: 2171 ILYTYAEDSGTYMCK 2185 + T ED+GTY CK Sbjct: 87 LRKTVREDTGTYSCK 101 >SB_55336| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 771 Score = 54.4 bits (125), Expect = 2e-06 Identities = 30/74 (40%), Positives = 37/74 (50%), Gaps = 9/74 (12%) Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561 VREG P++L+ A G P P W KDG + TD STL+I A DA Y Sbjct: 75 VREGNPLILSCAADGRPIPSYEWLKDG---------HVITDSSNSTLEIESASREDAGRY 125 Query: 562 QCTAQNVAGSTATR 575 QC A N G+ +R Sbjct: 126 QCVASNRIGNETSR 139 Score = 53.6 bits (123), Expect = 4e-06 Identities = 55/178 (30%), Positives = 77/178 (43%), Gaps = 30/178 (16%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTL 4571 PP TL + V G + L G +PI Y WLK+G ++ + TL Sbjct: 63 PPVITLQPEPTVVREGNPLILSCAADG-RPIPSYEWLKDGH---------VITDSSNSTL 112 Query: 4572 LILEAYPQDSGKYECVAINSAG-EARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PL 4629 I A +D+G+Y+CVA N G E A+ V P T + + +T I++ PL Sbjct: 113 EIESASREDAGRYQCVASNRIGNETSRYADVTVYYPPTVNLTEKRT--------IVKLPL 164 Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKG-DKLIKPSKYFQMS-RTADEYTLRISEA 4685 G + SC VG P P QWYKG D I + ++ T EY + EA Sbjct: 165 -------GASETLSCPAVGNPSPIYQWYKGIDHYISNGHHISVTVATEAEYVTYLCEA 215 Score = 48.0 bits (109), Expect = 2e-04 Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 9/84 (10%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 PP I + +V EG + SC G+P+P+ +W K +I S TL Sbjct: 63 PPVITLQPEPTVVREGNPLILSCAADGRPIPSYEWLKDGHVITDS---------SNSTLE 113 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVT 4705 I A ED G Y+CVA N G T Sbjct: 114 IESASREDAGRYQCVASNRIGNET 137 Score = 46.4 bits (105), Expect = 6e-04 Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 24/170 (14%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V EG C GRP P W ++D + ++ +S N L I + + D+G Sbjct: 75 VREGNPLILSCAADGRPIPSYEW------LKDGH----VITDSSNSTLEIESASREDAGR 124 Query: 463 VTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521 CVA N+ G ET+ + V V E+ + + + G L+ AVG P+P Sbjct: 125 YQCVASNRIGNETSRYADVTVYYPPTV---NLTEKRTIVKLPLGASETLSCPAVGNPSPI 181 Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 W K G+ H + + A ++ Y C A+N G+ Sbjct: 182 YQWYK-GID---------HYISNGHHISVTVATEAEYVTYLCEAENELGT 221 Score = 40.3 bits (90), Expect = 0.037 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 9/81 (11%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PP I +P + ++EG G P P W K+G +IT +++TL Sbjct: 63 PPVITLQPEPTVVREGNPLILSCAADGRPIPSYEWLKDG---------HVITDSSNSTLE 113 Query: 325 VRNTQKSDSGHYTLLAENPNG 345 + + + D+G Y +A N G Sbjct: 114 IESASREDAGRYQCVASNRIG 134 Score = 39.1 bits (87), Expect = 0.086 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 12/89 (13%) Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752 +PP T++ + + V EG P+ C + G P +W +G H + D Sbjct: 62 DPPVITLQPEPTV-VREGNPLILSCAAD--GRPIPSYEWLKDG---------HVITDSSN 109 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATT 3781 L+I+ DAG Y C A+N+ G+ T+ Sbjct: 110 STLEIESASREDAGRYQCVASNRIGNETS 138 Score = 37.5 bits (83), Expect = 0.26 Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 15/117 (12%) Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748 DEG+Y+ +A + L VT P P T VV EG P + Sbjct: 37 DEGEYQLRLRGTAKPLDSVIALFVTDPPVITLQPEPT-----VVREGNPLILSCAADGRP 91 Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805 P+ +WL++G +I + +N+ L I + ED G + C A+ G ETS Sbjct: 92 IPSYEWLKDG---------HVITDSSNSTLEIESASREDAGRYQCVASNRIGN-ETS 138 Score = 36.7 bits (81), Expect = 0.46 Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 10/59 (16%) Query: 944 EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS-ANLTI 1001 EWLKDG + SS T L I+S + DAG Y C A N IG T+ A++T+ Sbjct: 96 EWLKDGHVITDSSNST---------LEIESASREDAGRYQCVASNRIGNETSRYADVTV 145 Score = 35.9 bits (79), Expect = 0.80 Identities = 17/50 (34%), Positives = 21/50 (42%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 PPV P+ V EG C G P P WL +G+ I + S L Sbjct: 63 PPVITLQPEPTVVREGNPLILSCAADGRPIPSYEWLKDGHVITDSSNSTL 112 Score = 35.1 bits (77), Expect = 1.4 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 11/87 (12%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903 P IT PT + EG C + P P+ EW L+ GH S++ + Sbjct: 63 PPVITLQPEPTVVREGNPLILSCAADGRPIPSY--EW------LKDGHVITDSSN---ST 111 Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVS 1930 L+I + ED+G Y C A N +G S Sbjct: 112 LEIESASREDAGRYQCVASNRIGNETS 138 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 PP+ T + +P V E DG P+P +W + D + T S+ S L Sbjct: 63 PPVITLQPEPTVVREGNPLILSCAADGRPIPSYEWLK---------DGHVITDSSNSTLE 113 Query: 4470 IRQVFVEDSAVFAAVAENRGG 4490 I ED+ + VA NR G Sbjct: 114 IESASREDAGRYQCVASNRIG 134 Score = 32.7 bits (71), Expect = 7.5 Identities = 40/138 (28%), Positives = 56/138 (40%), Gaps = 19/138 (13%) Query: 2326 CTSAISMTV---TAKGSIISESQRP--EGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQ 2380 C+S S + T+K S I R EG ++R +A+P I VT + Q Sbjct: 11 CSSGKSSEIIQPTSKASFILNDIRDSDEGEYQLRLRGTAKPLDSV-IALFVTDPPVITLQ 69 Query: 2381 PLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISH 2440 P + ++EG C G P EW ++ +I DSS T + I Sbjct: 70 PEPTV--VREGNPLILSCAAD--GRPIPSYEWLKDGHVITDSSNST---------LEIES 116 Query: 2441 VRDEDEGVYMCRASNLLG 2458 ED G Y C ASN +G Sbjct: 117 ASREDAGRYQCVASNRIG 134 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 11/73 (15%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 EG + L + R P+ EW K+G +T D TL I S +D+G Y Sbjct: 77 EGNPLILSCAADGRPIPSY--EWLKDGHVIT---------DSSNSTLEIESASREDAGRY 125 Query: 2716 TCKATNLLGEAVS 2728 C A+N +G S Sbjct: 126 QCVASNRIGNETS 138 >SB_55607| Best HMM Match : ig (HMM E-Value=4.6e-17) Length = 274 Score = 54.0 bits (124), Expect = 3e-06 Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 20/209 (9%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP-IKNSPDFQIHTFSTKSIL 4468 PPI T + G P P ++W + P ++ +I + +IL Sbjct: 5 PPIITSRSNVHEAKVGSDVAVACVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAIL 64 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528 I V ED ++ VA N G +K ++V+ R I+PP + +Q V T+ Sbjct: 65 TIESVTKEDEGIYCCVARNSNGQSK--PHIVILSVSYHKR--ILPPHVSPFSQVVVSTTD 120 Query: 4529 QLVRLDTKVTGT--KPIDVYWLKNGKKVQPDIRNK-------------ILEEDGTYTLLI 4573 L V K V+W N K++ R K +L E T TL+I Sbjct: 121 STTTLICAVENAPQKYTTVFWTLNSKQLTDGGRYKMATTFSTEVEYKRLLLERATMTLII 180 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECV 4602 QDSG+Y+C + G + + V Sbjct: 181 KHVTTQDSGEYQCGVVTHIGSGHAEIQLV 209 Score = 46.0 bits (104), Expect = 8e-04 Identities = 26/90 (28%), Positives = 39/90 (43%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C TG P P V W + +VN+ L I +VT D G+ CVARN +G Sbjct: 27 CVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNG 86 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502 ++ + + + + P V FS + V Sbjct: 87 QSKPHIVILSVSYHKRILPPHVSPFSQVVV 116 Score = 41.1 bits (92), Expect = 0.021 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 3/60 (5%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQYGEA 155 G+P P V W+ + PL +C S G ++L I+ + DEG Y C ARN G++ Sbjct: 31 GSPKPTVEWSSQ--PLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQS 88 Score = 39.9 bits (89), Expect = 0.049 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 7/86 (8%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLP---SGTRYKSTHDFSYV 2831 + S N K G ++ C S PT +EW +++PLP S +R K + S Sbjct: 7 IITSRSNVHEAKVGSDVAVACVATGSPKPT--VEW--SSQPLPQCRSLSRAKIVNQGSTA 62 Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSA 2857 L I +ED GIY C A NS G + Sbjct: 63 ILTIESVTKEDEGIYCCVARNSNGQS 88 Score = 39.1 bits (87), Expect = 0.086 Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS-NKHEIITTHNHTTL 323 PP I + + + G+D +G+P+P V W S ++ +I+ + L Sbjct: 5 PPIITSRSNVHEAKVGSDVAVACVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAIL 64 Query: 324 RVRNTQKSDSGHYTLLAENPNG 345 + + K D G Y +A N NG Sbjct: 65 TIESVTKEDEGIYCCVARNSNG 86 Score = 39.1 bits (87), Expect = 0.086 Identities = 45/195 (23%), Positives = 74/195 (37%), Gaps = 23/195 (11%) Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGD----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692 G + +C G P PTV+W + + +K TA L I EDEG Sbjct: 20 GSDVAVACVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTA---ILTIESVTKEDEGI 76 Query: 4693 YKCVAYNSAGR-------VTVAAKLKVTQPDQADNLPALTPLRD-----IVVYEGQPAQF 4740 Y CVA NS G+ ++V+ ++ P + + D I E P ++ Sbjct: 77 YCCVARNSNGQSKPHIVILSVSYHKRILPPHVSPFSQVVVSTTDSTTTLICAVENAPQKY 136 Query: 4741 KT---QITSK-IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796 T + SK + ++ E +++ E L+I + +D+G + C Sbjct: 137 TTVFWTLNSKQLTDGGRYKMATTFSTEVEYKRLLLERATMTLIIKHVTTQDSGEYQCGVV 196 Query: 4797 TAAGQVETSAKLVVK 4811 T G +LV K Sbjct: 197 THIGSGHAEIQLVTK 211 Score = 36.7 bits (81), Expect = 0.46 Identities = 28/99 (28%), Positives = 37/99 (37%), Gaps = 13/99 (13%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF-- 1234 P V P S + L C +E V W N + +T G R+K F Sbjct: 105 PPHVSPFSQVVVSTTDSTTTLICAVENAPQKYTTVFWTLNSKQLTDGGRYKMATTFSTEV 164 Query: 1235 -----------VALDIIHATSADTGEYTVRAVNHLGSAH 1262 + L I H T+ D+GEY V H+GS H Sbjct: 165 EYKRLLLERATMTLIIKHVTTQDSGEYQCGVVTHIGSGH 203 Score = 35.5 bits (78), Expect = 1.1 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 3591 VEWFHNGKPLLTG-SRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA 3641 VEW P SR K +N IL I V + D G+Y C A N +G++ Sbjct: 37 VEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQS 88 Score = 35.1 bits (77), Expect = 1.4 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 1076 TVEWYFNG-KQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQ 1128 TVEW Q S +R + + L I SV ED G+Y VARN+ G+++ Sbjct: 36 TVEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQSK 89 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/85 (28%), Positives = 30/85 (35%), Gaps = 3/85 (3%) Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-RHSTRIKTVSDFGFV 3207 P T N+ K G C V P +EW P R +R K V+ Sbjct: 5 PPIITSRSNVHEAKVGSDVAVAC--VATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTA 62 Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGE 3232 +L I D G Y C A N G+ Sbjct: 63 ILTIESVTKEDEGIYCCVARNSNGQ 87 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/83 (24%), Positives = 31/83 (37%), Gaps = 1/83 (1%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN-PELRIHTDGGASTLD 549 P R + + G V + A G+P P + W +P + +I G + L Sbjct: 6 PIITSRSNVHEAKVGSDVAVACVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAILT 65 Query: 550 IPRAKASDAAWYQCTAQNVAGST 572 I D Y C A+N G + Sbjct: 66 IESVTKEDEGIYCCVARNSNGQS 88 Score = 33.5 bits (73), Expect = 4.3 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 1735 IPVGDPKLRVEWLRNGVP-IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793 + G PK VEW +P + +R ++ L ++ V ED G Y C A N G+ Sbjct: 28 VATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQ 87 Query: 1794 A 1794 + Sbjct: 88 S 88 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVA-LTIKSVTVHDAGHYTCRAYNAIGQA 993 VEW P S N G A LTI+SVT D G Y C A N+ GQ+ Sbjct: 37 VEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQS 88 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/85 (28%), Positives = 32/85 (37%), Gaps = 4/85 (4%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNE-KLIEDSSRITKTHDFGYV 2434 P+ T N+ + G C + G P VEW SR + Sbjct: 6 PIITSR-SNVHEAKVGSDVAVAC--VATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTA 62 Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459 +TI V EDEG+Y C A N G+ Sbjct: 63 ILTIESVTKEDEGIYCCVARNSNGQ 87 Score = 33.1 bits (72), Expect = 5.7 Identities = 36/173 (20%), Positives = 53/173 (30%), Gaps = 14/173 (8%) Query: 3073 IPTGDQSMVIEWFYNG-KTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131 + TG +EW + R + V +L I D G Y C A N GQ Sbjct: 28 VATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQ 87 Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191 ++ + + V K P + + + C V + W N + Sbjct: 88 SKPHIVILSVSYHKRILPPHVSPFSQVVVSTTDSTTTLICAVENAPQKYTTVFWTLNSKQ 147 Query: 3192 MRHSTRIKTVSDFGFVV-------------LDIAYTQNHDSGEYVCRAYNKYG 3231 + R K + F V L I + DSGEY C G Sbjct: 148 LTDGGRYKMATTFSTEVEYKRLLLERATMTLIIKHVTTQDSGEYQCGVVTHIG 200 >SB_37708| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1926 Score = 54.0 bits (124), Expect = 3e-06 Identities = 49/192 (25%), Positives = 72/192 (37%), Gaps = 26/192 (13%) Query: 390 LAPQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGN 447 + P+ + + +T+ G C V G P P +TW + D ++R S Sbjct: 1689 MRPKLLSYPSNYTITQIGSRVTLTCEVRGIPTPNITWSKLGDPRLR-----------STG 1737 Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GE 506 I+ T+ D G+ C A N G L + + PK + S + + G Sbjct: 1738 STFTISGFTVEDRGIYVCTASNGIGTNVTAVSL---VQYIGLRPKLLSYPSNHTITQIGN 1794 Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566 + L G PTP ITW K G P++ + ST I D Y CTA Sbjct: 1795 RLTLTCEVQGIPTPNITWSKLGDPLLRSK---------GSTFTISGFTVEDRGIYVCTAS 1845 Query: 567 NVAGSTATRARL 578 N G+ T L Sbjct: 1846 NGIGTNVTAVSL 1857 Score = 49.6 bits (113), Expect = 6e-05 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 9/75 (12%) Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561 VREG+P++L A G P+P TW DG ++ D T+ + RA+ DA Y Sbjct: 627 VREGKPLILTCVADGRPSPSYTWILDG---------QVIQDSFNGTVKVERARREDAGSY 677 Query: 562 QCTAQNVAGSTATRA 576 +C A N GS +R+ Sbjct: 678 RCVANNSIGSQTSRS 692 Score = 48.8 bits (111), Expect = 1e-04 Identities = 39/169 (23%), Positives = 63/169 (37%), Gaps = 22/169 (13%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V EGK C GRP P TW ++ + I+D +N + V + D+G Sbjct: 627 VREGKPLILTCVADGRPSPSYTWILDGQVIQDSFNGTVKVERARR----------EDAGS 676 Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522 CVA N G + ++ +V + + + + G L+ A G P P Sbjct: 677 YRCVANNSIGSQTSRSADVTVQFPPIV--NLTRKLTIVKLPLGASDTLSCPAEGNPAPYF 734 Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 W +D + + L + + A +D Y C A N G+ Sbjct: 735 RWYRDATHYVRDGHL----------VSVTVATEADYVTYMCEAVNEIGA 773 Score = 44.0 bits (99), Expect = 0.003 Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 23/189 (12%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 PP+I + +V EG+ + +C G+P P+ W ++I+ S T++ Sbjct: 615 PPKITLHPEPTVVREGKPLILTCVADGRPSPSYTWILDGQVIQDSF---------NGTVK 665 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTV-AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740 + A ED G Y+CVA NS G T +A + V P + LT ++ + G Sbjct: 666 VERARREDAGSYRCVANNSIGSQTSRSADVTVQFPPIVNLTRKLTIVK---LPLGASDTL 722 Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 P +W R+ + +G+ + + E D T+ C A G Sbjct: 723 SCPAEGNPAPYFRWYRDAT--------HYVRDGHLVSVTVAT--EADYVTYMCEAVNEIG 772 Query: 4801 QVETSAKLV 4809 + KLV Sbjct: 773 ADNATFKLV 781 Score = 39.5 bits (88), Expect = 0.065 Identities = 38/125 (30%), Positives = 46/125 (36%), Gaps = 17/125 (13%) Query: 460 SGVV-TCVARNKSGETAF-----QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513 SGV+ TC +RN S CR++ + P + S VR G V L Sbjct: 1321 SGVIKTCSSRNSSSVQRVTWVFPSCRID--RYFFLGKPTLLSYPSNHTVRNGTSVRLECH 1378 Query: 514 AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 G PTP ITW K G P S +I D Y CTA N G+ Sbjct: 1379 VKGKPTPIITWTKFGSP---------QWLSSGSVANISNVTTEDRGIYVCTASNGIGTNV 1429 Query: 574 TRARL 578 T L Sbjct: 1430 TAVSL 1434 Score = 39.1 bits (87), Expect = 0.086 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 9/81 (11%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PPKI P + ++EG G P P TW +GQ +I + T++ Sbjct: 615 PPKITLHPEPTVVREGKPLILTCVADGRPSPSYTWILDGQ---------VIQDSFNGTVK 665 Query: 325 VRNTQKSDSGHYTLLAENPNG 345 V ++ D+G Y +A N G Sbjct: 666 VERARREDAGSYRCVANNSIG 686 Score = 37.9 bits (84), Expect = 0.20 Identities = 49/205 (23%), Positives = 75/205 (36%), Gaps = 36/205 (17%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 PP TL + V G+ + L G W+ +G+ +Q T+ Sbjct: 615 PPKITLHPEPTVVREGKPLILTCVADGRPSPSYTWILDGQVIQDSFNG---------TVK 665 Query: 4573 ILEAYPQDSGKYECVAINSAG-EARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLK 4630 + A +D+G Y CVA NS G + A+ V P + + T I++ PL Sbjct: 666 VERARREDAGSYRCVANNSIGSQTSRSADVTVQFPPIVNLTRKLT--------IVKLPL- 716 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 G + SC G P P +WY+ + Y + D + + ++ A D Sbjct: 717 ------GASDTLSCPAEGNPAPYFRWYR-----DATHYVR-----DGHLVSVTVATEADY 760 Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQP 4715 Y C A N G KL P Sbjct: 761 VTYMCEAVNEIGADNATFKLVQVGP 785 Score = 37.5 bits (83), Expect = 0.26 Identities = 37/133 (27%), Positives = 53/133 (39%), Gaps = 14/133 (10%) Query: 3110 ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHF 3169 I G D G Y C A+N G +V L + G +P+ ++ N + G Sbjct: 1742 ISGFTVEDRGIYVCTASNGIGTNVTAVSLV---QYIGLRPKLLSYPSNHTITQIGNRLTL 1798 Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229 C V + P+ I W G P+ S + T + GF V D G YVC A N Sbjct: 1799 TCEVQGIPTPN--ITWSKLGDPLLRS-KGSTFTISGFTV--------EDRGIYVCTASNG 1847 Query: 3230 YGEDFTRATINCY 3242 G + T ++ Y Sbjct: 1848 IGTNVTAVSLVQY 1860 Score = 37.1 bits (82), Expect = 0.35 Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 21/188 (11%) Query: 4623 PEIIE-PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 P+++ P I G + +C++ G P P + W KL P ++ T +T Sbjct: 1691 PKLLSYPSNYTITQIGSRVTLTCEVRGIPTPNITW---SKLGDP----RLRSTGSTFT-- 1741 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741 IS ED G Y C A N G A L V L + P + G Sbjct: 1742 ISGFTVEDRGIYVCTASNGIGTNVTAVSL-VQYIGLRPKLLSY-PSNHTITQIGNRLTLT 1799 Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 ++ P I W + G ++ + + G T ED G + C A+ G Sbjct: 1800 CEVQGIPTPNITWSKLGD--------PLLRSKGSTFTISGFTV-EDRGIYVCTASNGIGT 1850 Query: 4802 VETSAKLV 4809 T+ LV Sbjct: 1851 NVTAVSLV 1858 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 11/90 (12%) Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889 P ++ +HTV VR EC V+ K P + + + + L SG Sbjct: 1356 PTLLSYPSNHTVRNGTSVRLECHVKGKPTPIITWTKFGSPQWLSSGS-----------VA 1404 Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 +I V ED G Y+C A N G + T ++ Sbjct: 1405 NISNVTTEDRGIYVCTASNGIGTNVTAVSL 1434 Score = 35.9 bits (79), Expect = 0.80 Identities = 22/88 (25%), Positives = 32/88 (36%), Gaps = 9/88 (10%) Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682 P ++ + V G ++ C + GKP P + W +K+ + I Sbjct: 1356 PTLLSYPSNHTVRNGTSVRLECHVKGKPTPIITW---------TKFGSPQWLSSGSVANI 1406 Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710 S ED G Y C A N G A L Sbjct: 1407 SNVTTEDRGIYVCTASNGIGTNVTAVSL 1434 Score = 35.5 bits (78), Expect = 1.1 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 13/88 (14%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSL-DI 2835 +S+ +N + G ++ EC+V+ PT I W T++ S S S+ +I Sbjct: 1359 LSYPSNHTVRNGTSVRLECHVKGK--PTPIITW----------TKFGSPQWLSSGSVANI 1406 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863 ++ ED GIY C A+N G+ T+ SL Sbjct: 1407 SNVTTEDRGIYVCTASNGIGTNVTAVSL 1434 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 3/63 (4%) Query: 1341 TMRVEWFCNGKP--IKTGHRF-RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397 ++R+E GKP I T +F P + ++ +V ED G+Y C A+N +G VT+ Sbjct: 1372 SVRLECHVKGKPTPIITWTKFGSPQWLSSGSVANISNVTTEDRGIYVCTASNGIGTNVTA 1431 Query: 1398 CAL 1400 +L Sbjct: 1432 VSL 1434 Score = 33.5 bits (73), Expect = 4.3 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 11/84 (13%) Query: 920 SIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDA 979 +++ G E ++ G T + W K G P SS G VA I +VT D Sbjct: 1366 TVRNGTSVRLECHVK--GKPTPIITWTKFGSPQWLSS--------GSVA-NISNVTTEDR 1414 Query: 980 GHYTCRAYNAIGQATTSANLTIVT 1003 G Y C A N IG T+ +L T Sbjct: 1415 GIYVCTASNGIGTNVTAVSLVQYT 1438 Score = 33.1 bits (72), Expect = 5.7 Identities = 14/42 (33%), Positives = 18/42 (42%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 PP P+ V EG+ C G P P W+L+G I Sbjct: 615 PPKITLHPEPTVVREGKPLILTCVADGRPSPSYTWILDGQVI 656 Score = 33.1 bits (72), Expect = 5.7 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 11/91 (12%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P ++ +Y G V L +V PN I W K G RL+ST T Sbjct: 1691 PKLLSYPSNYTITQIGSRVTLTCEVRGIPTPN--ITWSKLG-----DPRLRSTGS----T 1739 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732 +I+ +D GIY C A+N +G V+ S+ Sbjct: 1740 FTISGFTVEDRGIYVCTASNGIGTNVTAVSL 1770 Score = 33.1 bits (72), Expect = 5.7 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 15/97 (15%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G T + W K G P+ S+ +TF TI TV D G Y C A N IG T+ Sbjct: 1804 GIPTPNITWSKLGDPL-LRSKGSTF--------TISGFTVEDRGIYVCTASNGIGTNVTA 1854 Query: 997 ANLTIVT--KKDIIAESQHPGGLEKIQYLEDASRYSK 1031 +L T KD A+ + P + + + E RYSK Sbjct: 1855 VSLVQYTGCTKD-CAKKEVPVHVISLLWTE---RYSK 1887 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 10/98 (10%) Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312 S IDR + P + P N ++ G + + + G P P +TW K G S Sbjct: 1344 SCRIDRYFF-LGKPTLLSYPSNHTVRNGTSVRLECHVKGKPTPIITWTKFGSPQWLS--- 1399 Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 + + + N D G Y A N G VT+ Sbjct: 1400 ------SGSVANISNVTTEDRGIYVCTASNGIGTNVTA 1431 Score = 32.7 bits (71), Expect = 7.5 Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 13/111 (11%) Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502 KP ++ P + V G V EC ++ + W K G P + G V Sbjct: 1355 KPTLLSYPSN-HTVRNGTSVRLECHVKGKPTPI--ITWTKFGSPQWLSS--------GSV 1403 Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLE 1553 A +I ++ ED GIY C A N +GT+ + L + T V + E G++ Sbjct: 1404 A-NISNVTTEDRGIYVCTASNGIGTNVTAVSLV-QYTGCTVGCVKKEVGIQ 1452 Score = 32.3 bits (70), Expect = 9.9 Identities = 39/153 (25%), Positives = 57/153 (37%), Gaps = 16/153 (10%) Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522 ST S I VED ++ A N GT + +LV G+ P + + + Sbjct: 1735 STGSTFTISGFTVEDRGIYVCTASNGIGTNVTAVSLVQYI-------GLRPKLLSYPSNH 1787 Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 G + L +V G ++ W K G P +R+K T+T+ +D G Sbjct: 1788 TITQIGNRLTLTCEVQGIPTPNITWSKLG---DPLLRSK----GSTFTISGFTV--EDRG 1838 Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615 Y C A N G V TKD K + Sbjct: 1839 IYVCTASNGIGTNVTAVSLVQYTGCTKDCAKKE 1871 >SB_16652| Best HMM Match : I-set (HMM E-Value=1.2e-37) Length = 552 Score = 54.0 bits (124), Expect = 3e-06 Identities = 78/331 (23%), Positives = 116/331 (35%), Gaps = 48/331 (14%) Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540 +A VA N GT S+ ++ + PP+ T +V V G L +GT Sbjct: 150 YACVASNTAGTGDNSSVVITVQD---------PPTITHPPSDVTVARGSAASLSCNASGT 200 Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600 P+++ W + G +G L I A QD G Y CV N A A A Sbjct: 201 PPLNISWSRPG---------SAFYYEGA-VLTIDSAATQDDGVYRCVVHNGAHCASRSAS 250 Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPL--KDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 +++ ++ K + NA ++ L + + + I C GKP + W Sbjct: 251 ATLNVNSSTLKHR-NLPDENAVGLVLNKLLCLNTVSTRIKGIILYCNTSGKPQANITW-S 308 Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718 G PS L ++ E G Y C A NS G +A + V P Sbjct: 309 G-----PS---GAGNLPSGNPLVLTSVIKEHAGKYLCNASNSMGWAVESAHVDVQYPPTI 360 Query: 4719 DNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778 P ++ Y G +S P I W + G IH VL Sbjct: 361 VTTP-----KNTTAYLGGNVTLYCNASSHPAPQIYWAKNG-----------IHIAMGEVL 404 Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809 + GT+TC A+ G T++ V Sbjct: 405 RVA-VSSSTAGTYTCTASNGDGANATASASV 434 Score = 49.2 bits (112), Expect = 8e-05 Identities = 78/306 (25%), Positives = 112/306 (36%), Gaps = 52/306 (16%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 PP N+ VT G V L TG++P++V W P+ L T L Sbjct: 2 PPRIHGITSNLTVTEGSNVALQCNATGSEPLNVTWR------SPN--GAFLSSGVTLNLN 53 Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632 IL D G Y+C A N E E V KP+ + A + Sbjct: 54 ILSR--NDEGSYQCSASN-GNECPVAEESVFVTVIY----KPENTSITA--------SKR 98 Query: 4633 IVAEGQAIEFSCKIVGKP-LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691 + ++ +C KP +Y+GD LI + T+ +T+ +S Sbjct: 99 MACVNDSVTLACASTAKPAADRYIYYRGDSLIH-------NGTSGTHTITLS---AHGTH 148 Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKP 4750 +Y CVA N+AG + + +T D P +T P D+ V G A + Sbjct: 149 EYACVASNTAG-TGDNSSVVITVQDP----PTITHPPSDVTVARGSAASLSCNASGTPPL 203 Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA--GQVETSAKL 4808 I W R G+ +EG AVL I + +D G + C A SA L Sbjct: 204 NISWSRPGS--------AFYYEG--AVLTIDSAATQDDGVYRCVVHNGAHCASRSASATL 253 Query: 4809 VVKSKT 4814 V S T Sbjct: 254 NVNSST 259 Score = 39.1 bits (87), Expect = 0.086 Identities = 66/312 (21%), Positives = 104/312 (33%), Gaps = 57/312 (18%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PP I P + + G+ A SG P ++W + G + L Sbjct: 173 PPTITHPPSDVTVARGSAASLSCNASGTPPLNISWSRPGSAFY----------YEGAVLT 222 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384 + + D G Y C+V +G ++ + + + + R Sbjct: 223 IDSAATQDDGVYR--------CVVHNG---------AHCASRSASATLNVNSSTLKHRNL 265 Query: 385 ISEKALAPQFVKV-CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443 E A+ K+ C + T K C +G+P +TW N Sbjct: 266 PDENAVGLVLNKLLCLNTVSTRIKGIILYCNTSGKPQANITWS----------GPSGAGN 315 Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA-PKFVERFSTLNV 502 + L++T+V +G C A N G ++V +V PK + Sbjct: 316 LPSGNPLVLTSVIKEHAGKYLCNASNSMGWAVESAHVDVQYPPTIVTTPKNTTAYL---- 371 Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562 G V L A P P+I W K+G+ I LR+ +S A Y Sbjct: 372 --GGNVTLYCNASSHPAPQIYWAKNGIHIAMGEVLRV------------AVSSSTAGTYT 417 Query: 563 CTAQNVAGSTAT 574 CTA N G+ AT Sbjct: 418 CTASNGDGANAT 429 Score = 38.3 bits (85), Expect = 0.15 Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 14/133 (10%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PP I P+N+ G + S +P P++ W KNG I+ E+ LR Sbjct: 357 PPTIVTTPKNTTAYLGGNVTLYCNASSHPAPQIYWAKNG---IHIAMGEV--------LR 405 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVT-SGYLAVE-SPTESYVQDQRSQYITDTQQRETEER 382 V S +G YT A N +G T S + VE E V+ + Y+ + + +++ + Sbjct: 406 VA-VSSSTAGTYTCTASNGDGANATASASVTVELYEAEVSVRCKDELYVAELKNKDSPQF 464 Query: 383 IEISEKALAPQFV 395 ++ ++ L + V Sbjct: 465 KDLEKRFLEQKCV 477 Score = 34.7 bits (76), Expect = 1.9 Identities = 15/45 (33%), Positives = 19/45 (42%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154 PP V+ P T G C + HP P++ W NG I G Sbjct: 357 PPTIVTTPKNTTAYLGGNVTLYCNASSHPAPQIYWAKNGIHIAMG 401 Score = 34.3 bits (75), Expect = 2.5 Identities = 16/48 (33%), Positives = 29/48 (60%) Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951 L + +V E +G+Y C A N++G AV S ++VQ +I+ ++ +A Sbjct: 322 LVLTSVIKEHAGKYLCNASNSMGWAVESAHVDVQYPPTIVTTPKNTTA 369 >SB_5575| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 234 Score = 54.0 bits (124), Expect = 3e-06 Identities = 51/158 (32%), Positives = 71/158 (44%), Gaps = 15/158 (9%) Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473 RV G P P +TW + +R + K VN+S +LMI DSG + +N G+ Sbjct: 72 RVFGFPPPNITW--SGPALR---HSKSRVNQSDG-SLMIMRTEFRDSGEYQAIVKNVVGQ 125 Query: 474 TAFQCRLNVIEKEQVVAPKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532 + L V Q VAP + +T L + E V+ + G P P I W K + Sbjct: 126 AVIRTFLVV---NQGVAPLLMSFPTTPLTIVENSTAVVPCISTGFPAPVINWTKIENSMD 182 Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 P+ R+ D A T I + SD Y C+A NVAG Sbjct: 183 PS---RMSYDSRALT--IKDVRLSDVGTYVCSATNVAG 215 Score = 48.0 bits (109), Expect = 2e-04 Identities = 42/172 (24%), Positives = 69/172 (40%), Gaps = 14/172 (8%) Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700 E ++ G P P + W G L ++ + + +L I D G+Y+ + N Sbjct: 68 ELQLRVFGFPPPNITW-SGPAL----RHSKSRVNQSDGSLMIMRTEFRDSGEYQAIVKNV 122 Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGA 4759 G+ + L V Q A L + P + + E A T P I W + E + Sbjct: 123 VGQAVIRTFLVVNQ-GVAPLLMSF-PTTPLTIVENSTAVVPCISTGFPAPVINWTKIENS 180 Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 + P + ++ L I + D GT+ C AT AGQV + ++VK Sbjct: 181 MDPSRMSY------DSRALTIKDVRLSDVGTYVCSATNVAGQVNGNVTVIVK 226 Score = 46.0 bits (104), Expect = 8e-04 Identities = 44/172 (25%), Positives = 73/172 (42%), Gaps = 23/172 (13%) Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592 L +V G P ++ W +G ++ ++++ + DG+ L+I+ +DSG+Y+ + N Sbjct: 69 LQLRVFGFPPPNITW--SGPALRHS-KSRVNQSDGS--LMIMRTEFRDSGEYQAIVKNVV 123 Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652 G+A VV+ AP + P + E C G P P Sbjct: 124 GQAVIRTFLVVNQGV-------------APLLMSFPTTPLTIVENSTAVVPCISTGFPAP 170 Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 + W K + + PS+ SR +R+S D G Y C A N AG+V Sbjct: 171 VINWTKIENSMDPSRMSYDSRALTIKDVRLS-----DVGTYVCSATNVAGQV 217 Score = 43.2 bits (97), Expect = 0.005 Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 11/133 (8%) Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV-REG 505 + AL+I +V SD G C A N+ G + VI + VAP+ ++ + Sbjct: 10 SQALIIKDVRYSDRGTYVCSATNEEGRV--NGTVTVIVQ---VAPRVHQQPKAIEFGYRP 64 Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565 L R G P P ITW P + + + R++ G +L I R + D+ YQ Sbjct: 65 ASKELQLRVFGFPPPNITWSG---PALRHSKSRVNQSDG--SLMIMRTEFRDSGEYQAIV 119 Query: 566 QNVAGSTATRARL 578 +NV G R L Sbjct: 120 KNVVGQAVIRTFL 132 Score = 35.9 bits (79), Expect = 0.80 Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 ALTIK V + D G Y C A N GQ + N+T++ K Sbjct: 192 ALTIKDVRLSDVGTYVCSATNVAGQ--VNGNVTVIVK 226 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 7/72 (9%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 I E TA C I G P + W + E + D SR++ + ++TI VR D G Sbjct: 152 IVENSTAVVPC--ISTGFPAPVINWTKIENSM-DPSRMS----YDSRALTIKDVRLSDVG 204 Query: 2448 VYMCRASNLLGE 2459 Y+C A+N+ G+ Sbjct: 205 TYVCSATNVAGQ 216 Score = 33.9 bits (74), Expect = 3.2 Identities = 43/217 (19%), Positives = 85/217 (39%), Gaps = 14/217 (6%) Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSV-YIQPEGXXXXXXXXXXXXXYRHVSETVEH 188 +L+IK + D G Y C+A N+ G +V I YR S+ ++ Sbjct: 12 ALIIKDVRYSDRGTYVCSATNEEGRVNGTVTVIVQVAPRVHQQPKAIEFGYRPASKELQL 71 Query: 189 KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES 248 + +G S + ++ + S + E+R E ++I K VG++ Sbjct: 72 RVFGFPPPNITWSGPA--LRHSKSRVNQSDGSLMIMRTEFRDSGEY---QAIVKNVVGQA 126 Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308 ++ +++ V+P ++ + E + A +G P P + W K I Sbjct: 127 VIRTFLVVNQG---VAPLLMSFPTTPLTIVENSTAVVPCISTGFPAPVINWTK-----IE 178 Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345 ++ +++ L +++ + SD G Y A N G Sbjct: 179 NSMDPSRMSYDSRALTIKDVRLSDVGTYVCSATNVAG 215 Score = 33.1 bits (72), Expect = 5.7 Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 13/148 (8%) Query: 1664 SGIAIVHSKKSIYLESQHEGALPRLN-QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRV 1722 SG A+ HSK + +Q +G+L + + D+ +YQ + V+ QA + T + + V Sbjct: 84 SGPALRHSKSRV---NQSDGSLMIMRTEFRDSGEYQ--AIVKNVVGQAVIRTFLVVNQGV 138 Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN--RLTTMHD-----FGYVALNMKYV 1775 A + L V + V + G P N ++ D + AL +K V Sbjct: 139 APLLMSFPTTPLTIVENSTAVVPCISTGFPAPVINWTKIENSMDPSRMSYDSRALTIKDV 198 Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 D GTY C A N G+ + T+ V+ Sbjct: 199 RLSDVGTYVCSATNVAGQVNGNVTVIVK 226 Score = 32.7 bits (71), Expect = 7.5 Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 12/129 (9%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I + +D GTY C ATN+ G+ +V + V + PR + IE S Sbjct: 13 LIIKDVRYSDRGTYVCSATNEEGRVNGTVTV-IVQVA----PRVHQQPKAIEFGYRPASK 67 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 + V P+ I W +G +RHS SD +++ T+ DSGEY Sbjct: 68 ELQLRVFGFPPPN--ITW--SGPALRHSKSRVNQSDGSLMIM---RTEFRDSGEYQAIVK 120 Query: 3228 NKYGEDFTR 3236 N G+ R Sbjct: 121 NVVGQAVIR 129 >SB_30961| Best HMM Match : I-set (HMM E-Value=0) Length = 1018 Score = 53.6 bits (123), Expect = 4e-06 Identities = 48/171 (28%), Positives = 69/171 (40%), Gaps = 21/171 (12%) Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461 DV E C +G P P +TW ++ I S L+ + SG Sbjct: 422 DVIENSTLIISCTASGFPEPSITWTGSNGSI-----------VSRTSLLIKKGIQREGSG 470 Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521 TC A+N G F RL I + +++ T+N E + ++L A G P P Sbjct: 471 DYTCEAQNVVG---FARRLVTINVHYPPSIEWITPHQTIN--ETDIILLYCNATGNPRPN 525 Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572 ITW V I ++ + GG S + + SDA Y C+A N G T Sbjct: 526 ITW----VKTINQGKVLLRNIGG-SVFQVGKNNRSDAGTYTCSATNYLGQT 571 Score = 48.8 bits (111), Expect = 1e-04 Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 14/127 (11%) Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTL 500 V ES N +I VT +D G C A N G A Q + V E+ ++ A + ++ Sbjct: 624 VTESSNATRVIHRVTKADQGSHECAAYNIMGWGKAAQLYVRVYERPRITA---ISPDVSV 680 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 + + V L A G P P ITW +G P+ N S + + +A Sbjct: 681 TINRTDSVTLKCHASGDPAPNITWSHEGAPLEHN----------GSMITLYNVTRREAGS 730 Query: 561 YQCTAQN 567 Y+C A N Sbjct: 731 YECKADN 737 Score = 45.2 bits (102), Expect = 0.001 Identities = 43/189 (22%), Positives = 74/189 (39%), Gaps = 22/189 (11%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P + + + E + C TG P P +TW ++ K+L+ G Sbjct: 495 PSIEWITPHQTINETDIILLYCNATGNPRPNITW------VKTINQGKVLLRNIGGSVFQ 548 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511 + SD+G TC A N G+T +++ K + + + +N E +VL Sbjct: 549 VGKNNRSDAGTYTCSATNYLGQTHGNTTVDIQYKPD-DSRLSIHDIAVIN----ETLVLK 603 Query: 512 ARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 A P P R ++ +G + T+ +T I R +D ++C A N+ G Sbjct: 604 CLADAVPQPSRYKFKVNGTTV---------TESSNATRVIHRVTKADQGSHECAAYNIMG 654 Query: 571 STATRARLY 579 A+LY Sbjct: 655 -WGKAAQLY 662 Score = 43.6 bits (98), Expect = 0.004 Identities = 65/291 (22%), Positives = 106/291 (36%), Gaps = 55/291 (18%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 PS + +N ++ G + L TG ++ W +N G L Sbjct: 242 PSIVTSPRNHSILEGTRLSLYCNATGFPEPEILW-----------QNSAYRTIGKGNFLT 290 Query: 4574 LEAYPQD-SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632 L + SG Y C+A+N G + +A + P PEII P + Sbjct: 291 LNKTDRVVSGTYTCLAVNLLGSYKANATVNILYP----------------PEIIHPPSRQ 334 Query: 4633 IVAEGQ--AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 V A+ +C + P+ TV Y+G ++ S + T ++ TL +D Sbjct: 335 SVTVNVTGALRLNCYAMANPIATVLIYRGLNVLN-SSLGEAQYTKNDVTL-------DDG 386 Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750 G+Y CVA N G T + V P +PA + V E + +P Sbjct: 387 GEYACVAKNGHGNTTRTMVVLVRYPPLNMTVPA-----RVDVIENSTLIISCTASGFPEP 441 Query: 4751 TIQWL-REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 +I W G+++ T ++L+ E +G +TC A G Sbjct: 442 SITWTGSNGSIVSRT-----------SLLIKKGIQREGSGDYTCEAQNVVG 481 Score = 42.3 bits (95), Expect = 0.009 Identities = 54/235 (22%), Positives = 85/235 (36%), Gaps = 38/235 (16%) Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 D G+Y CVA N G +V P P + P + ++ E Sbjct: 385 DGGEYACVAKNGHGNTTRTMVVLVRYP---------------PLNMTVPARVDVI-ENST 428 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP-EDEGDYKCVAY 4698 + SC G P P++ W + I +SRT +L I + E GDY C A Sbjct: 429 LIISCTASGFPEPSITWTGSNGSI-------VSRT----SLLIKKGIQREGSGDYTCEAQ 477 Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758 N G + V P ++ +TP + + E T +P I W++ Sbjct: 478 NVVGFARRLVTINVHYP---PSIEWITPHQ--TINETDIILLYCNATGNPRPNITWVK-- 530 Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813 ++ +V +G D GT+TC AT GQ + + ++ K Sbjct: 531 ---TINQGKVLLRNIGGSVFQVGKNNRSDAGTYTCSATNYLGQTHGNTTVDIQYK 582 Score = 40.7 bits (91), Expect = 0.028 Identities = 40/131 (30%), Positives = 54/131 (41%), Gaps = 16/131 (12%) Query: 441 LVNESGNHALMITN-VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499 ++N S A N VTL D G CVA+N G T R V+ P + + Sbjct: 366 VLNSSLGEAQYTKNDVTLDDGGEYACVAKNGHGNTT---RTMVVLVRY--PPLNMTVPAR 420 Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559 ++V E ++++ A G P P ITW I+ L I I R + D Sbjct: 421 VDVIENSTLIISCTASGFPEPSITWTGSNGSIVSRTSLLIKK-------GIQREGSGD-- 471 Query: 560 WYQCTAQNVAG 570 Y C AQNV G Sbjct: 472 -YTCEAQNVVG 481 Score = 39.9 bits (89), Expect = 0.049 Identities = 39/159 (24%), Positives = 69/159 (43%), Gaps = 18/159 (11%) Query: 4660 DKLIKPSKY-FQMSRT----ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714 D + +PS+Y F+++ T + T I D+G ++C AYN G AA+L V + Sbjct: 607 DAVPQPSRYKFKVNGTTVTESSNATRVIHRVTKADQGSHECAAYNIMG-WGKAAQLYV-R 664 Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774 + + A++P + + K + P I W EGA + E N Sbjct: 665 VYERPRITAISPDVSVTINRTDSVTLKCHASGDPAPNITWSHEGAPL----------EHN 714 Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVVKS 4812 +++ + N + G++ C+A + + SA L V S Sbjct: 715 GSMITLYNVTRREAGSYECKADNGIRKPAKASAVLSVNS 753 Score = 39.1 bits (87), Expect = 0.086 Identities = 21/42 (50%), Positives = 26/42 (61%), Gaps = 1/42 (2%) Query: 1913 DSGEYTCKAINNLGQAVS-SIRLNVQSKESIIRDSQHESALE 1953 D GEYTC A N+ G+ VS S L VQ K SI+ ++ S LE Sbjct: 214 DGGEYTCTANNSFGKPVSASFFLTVQYKPSIVTSPRNHSILE 255 Score = 39.1 bits (87), Expect = 0.086 Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 4/113 (3%) Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684 I +P K V +I +C + G PLP+V W + K + S F R L + Sbjct: 739 IRKPAKASAVLSVNSINLTCDVEGGPLPSVTWSR--KRSQFSIIFSPVRMRS--VLEVIP 794 Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737 D GDY C+A N G + L P A A+T V QP Sbjct: 795 KQSRDFGDYICMARNIMGWNSHTLTLTRVDPPGAPKELAVTSFHHRVTIRWQP 847 Score = 38.3 bits (85), Expect = 0.15 Identities = 40/164 (24%), Positives = 57/164 (34%), Gaps = 25/164 (15%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C +GRP P +TW +H + S L T + D G TC A N G Sbjct: 179 CTASGRPKPLITW-----------SHAPKGHVSMTQWLNKTLIDRHDGGEYTCTANNSFG 227 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532 + ++ + P V ++ EG + L A G P P I WQ Sbjct: 228 KPVSASFFLTVQYK----PSIVTSPRNHSILEGTRLSLYCNATGFPEPEILWQNSA---- 279 Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 T G + L + + + Y C A N+ GS A Sbjct: 280 ------YRTIGKGNFLTLNKTDRVVSGTYTCLAVNLLGSYKANA 317 Score = 36.7 bits (81), Expect = 0.46 Identities = 40/185 (21%), Positives = 67/185 (36%), Gaps = 24/185 (12%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 PP + + I C G+P P + W P + M++ ++ + Sbjct: 157 PPVMTSSPSNTTANVSDVISLQCTASGRPKPLITWSHA-----PKGHVSMTQWLNKTLID 211 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741 D G+Y C A NS G+ A+ Q + +T R+ + EG Sbjct: 212 -----RHDGGEYTCTANNSFGKPVSASFFLTVQYKPS----IVTSPRNHSILEGTRLSLY 262 Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 T +P I W + ++ I +GN L + T +GT+TC A G Sbjct: 263 CNATGFPEPEILW--------QNSAYRTIGKGN--FLTLNKTDRVVSGTYTCLAVNLLGS 312 Query: 4802 VETSA 4806 + +A Sbjct: 313 YKANA 317 Score = 36.3 bits (80), Expect = 0.61 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 5/78 (6%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PP I + + E +GNPRP +TW K IN K ++ + + Sbjct: 494 PPSIEWITPHQTINETDIILLYCNATGNPRPNITWVKT----INQGK-VLLRNIGGSVFQ 548 Query: 325 VRNTQKSDSGHYTLLAEN 342 V +SD+G YT A N Sbjct: 549 VGKNNRSDAGTYTCSATN 566 Score = 35.9 bits (79), Expect = 0.80 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 10/95 (10%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P I PRN + EG +G P P + W + R I N TL Sbjct: 242 PSIVTSPRNHSILEGTRLSLYCNATGFPEPEILWQNSAYRTIGKG--------NFLTL-- 291 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360 T + SG YT LA N G + + + P E Sbjct: 292 NKTDRVVSGTYTCLAVNLLGSYKANATVNILYPPE 326 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G+P+ + W++ + + + G + N D+GTYTC A N LG+ + Sbjct: 520 GNPRPNITWVKT-----INQGKVLLRNIGGSVFQVGKNNRSDAGTYTCSATNYLGQTHGN 574 Query: 1798 STLFVQSKASLQLESQHESAL 1818 +T+ +Q K S H+ A+ Sbjct: 575 TTVDIQYKPDDSRLSIHDIAV 595 Score = 35.1 bits (77), Expect = 1.4 Identities = 42/181 (23%), Positives = 66/181 (36%), Gaps = 22/181 (12%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P V ++ + EG C TG P PE+ W N GN L Sbjct: 242 PSIVTSPRNHSILEGTRLSLYCNATGFPEPEILW----------QNSAYRTIGKGNF-LT 290 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511 + SG TC+A N G +N++ +++ P + T+NV + LN Sbjct: 291 LNKTDRVVSGTYTCLAVNLLGSYKANATVNILYPPEIIHPP-SRQSVTVNVTGA--LRLN 347 Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 A+ P + + G+ ++ + TLD D Y C A+N G+ Sbjct: 348 CYAMANPIATVLIYR-GLNVLNSSLGEAQYTKNDVTLD-------DGGEYACVAKNGHGN 399 Query: 572 T 572 T Sbjct: 400 T 400 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/99 (24%), Positives = 43/99 (43%), Gaps = 11/99 (11%) Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 + + P T D+ V N+ + GDP + W G P+E + + T+++ Sbjct: 665 VYERPRITAISPDVSVTINRTDSVTLKCHASGDPAPNITWSHEGAPLEHNGSMITLYN-- 722 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGE-AVTSSTLFVQS 1804 V ++G+Y C+A N + + A S+ L V S Sbjct: 723 --------VTRREAGSYECKADNGIRKPAKASAVLSVNS 753 Score = 34.7 bits (76), Expect = 1.9 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSS-TLFVQSKASLQLESQHESALQ 1819 LN ++ D G YTC A N G+ V++S L VQ K S+ ++ S L+ Sbjct: 205 LNKTLIDRHDGGEYTCTANNSFGKPVSASFFLTVQYKPSIVTSPRNHSILE 255 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/111 (25%), Positives = 40/111 (36%), Gaps = 10/111 (9%) Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 V PP + P N+ Q SG P+P +TW H +T + T Sbjct: 155 VDPPVMTSSPSNTTANVSDVISLQCTASGRPKPLITWSH------APKGHVSMTQWLNKT 208 Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373 L + D G YT A N G V++ + S V R+ I + Sbjct: 209 L----IDRHDGGEYTCTANNSFGKPVSASFFLTVQYKPSIVTSPRNHSILE 255 Score = 33.5 bits (73), Expect = 4.3 Identities = 16/40 (40%), Positives = 23/40 (57%) Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952 D+G YTC A N LGQ + +++Q K R S H+ A+ Sbjct: 556 DAGTYTCSATNYLGQTHGNTTVDIQYKPDDSRLSIHDIAV 595 Score = 33.5 bits (73), Expect = 4.3 Identities = 25/118 (21%), Positives = 48/118 (40%), Gaps = 11/118 (9%) Query: 913 TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIK 972 T I +S+ + GD + W +G P+E + + T +N Sbjct: 672 TAISPDVSVTINRTDSVTLKCHASGDPAPNITWSHEGAPLEHNGSMITLYN--------- 722 Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYS 1030 VT +AG Y C+A N I + ++ + V ++ + + G L + + S++S Sbjct: 723 -VTRREAGSYECKADNGIRKPAKASAVLSVNSINLTCDVE-GGPLPSVTWSRKRSQFS 778 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/58 (43%), Positives = 29/58 (50%), Gaps = 11/58 (18%) Query: 3597 GKPLLTGSRVKTINDFGFVILEIGG-VYQ------RDAGLYTCKATN----RHGEATV 3643 G P + VKTIN ++ IGG V+Q DAG YTC ATN HG TV Sbjct: 520 GNPRPNITWVKTINQGKVLLRNIGGSVFQVGKNNRSDAGTYTCSATNYLGQTHGNTTV 577 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/112 (22%), Positives = 50/112 (44%), Gaps = 13/112 (11%) Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498 +V KP VT P++ +++EG + C + ++ W + +R I Sbjct: 237 TVQYKPSIVTSPRN-HSILEGTRLSLYCNATGFPEP--EILWQNSA--------YRTIGK 285 Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550 ++ L+ D + SG YTC AVNL+G+ + + + +I+ ++ Sbjct: 286 GNFLTLNKTDRVV--SGTYTCLAVNLLGSYKANATVNILYPPEIIHPPSRQS 335 Score = 32.7 bits (71), Expect = 7.5 Identities = 14/46 (30%), Positives = 24/46 (52%) Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN 4153 R PP+ +++P V V E C +G P+P + W + +IV+ Sbjct: 409 RYPPLNMTVPARVDVIENSTLIISCTASGFPEPSITWTGSNGSIVS 454 Score = 32.7 bits (71), Expect = 7.5 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 9/76 (11%) Query: 2660 VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKA 2719 +Y A PR PN I W K T+ G L + G + D+G YTC A Sbjct: 514 LYCNATGNPR--PN--ITWVK---TINQGKVLLR--NIGGSVFQVGKNNRSDAGTYTCSA 564 Query: 2720 TNLLGEAVSTASIKIE 2735 TN LG+ ++ I+ Sbjct: 565 TNYLGQTHGNTTVDIQ 580 >SB_10041| Best HMM Match : ig (HMM E-Value=3.5e-06) Length = 333 Score = 53.6 bits (123), Expect = 4e-06 Identities = 38/154 (24%), Positives = 60/154 (38%), Gaps = 11/154 (7%) Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434 Q +E+ I ++ + DV E C +GRP P VTW +N Sbjct: 184 QALPSEKAIPVTSRQRKRLNNNTATSHDVAEHDDFNVTCSASGRPAPNVTW-VNKT---- 238 Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494 + + + +G+ L + + +GV C A N G+ A + + V P + Sbjct: 239 --SGSPVAHGTGSATLSLLKIQRHQAGVYQCQATNDVGKGAITQDVTI----NVQYPPEI 292 Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528 VR GE + L G PTP ++W K G Sbjct: 293 TPMHNTTVRAGETITLTCTVAGNPTPSVSWSKAG 326 Score = 42.7 bits (96), Expect = 0.007 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 15/92 (16%) Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626 G+ TL +L+ +G Y+C A N G+ + +++ PPEI Sbjct: 248 GSATLSLLKIQRHQAGVYQCQATNDVGKGAITQDVTINV--------------QYPPEIT 293 Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 P+ + V G+ I +C + G P P+V W K Sbjct: 294 -PMHNTTVRAGETITLTCTVAGNPTPSVSWSK 324 Score = 40.7 bits (91), Expect = 0.028 Identities = 28/128 (21%), Positives = 49/128 (38%), Gaps = 14/128 (10%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 VAE +C G+P P V W + + ++ TL + + G Y Sbjct: 212 VAEHDDFNVTCSASGRPAPNVTW------VNKTSGSPVAHGTGSATLSLLKIQRHQAGVY 265 Query: 4694 KCVAYNSAGR--VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751 +C A N G+ +T + V P P +TP+ + V G+ + P+ Sbjct: 266 QCQATNDVGKGAITQDVTINVQYP------PEITPMHNTTVRAGETITLTCTVAGNPTPS 319 Query: 4752 IQWLREGA 4759 + W + G+ Sbjct: 320 VSWSKAGS 327 Score = 32.7 bits (71), Expect = 7.5 Identities = 13/37 (35%), Positives = 22/37 (59%) Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 G TLS+ ++ +G+Y C+ATN +G+ T + I Sbjct: 248 GSATLSLLKIQRHQAGVYQCQATNDVGKGAITQDVTI 284 >SB_46550| Best HMM Match : Asn_synthase (HMM E-Value=0) Length = 1663 Score = 52.4 bits (120), Expect = 9e-06 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685 EPL+D V + E +CKI P V W D + + +++SRT D +TL++ Sbjct: 880 EPLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPL 939 Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 D G Y C+A + AG AK+ V Sbjct: 940 AVADTGYYTCIASSPAGSARSTAKVTV 966 Score = 46.0 bits (104), Expect = 8e-04 Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 4/92 (4%) Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGN-HALM 451 F + QD V + T C+++ +P +V+W ND + D N K ++ +G+ H L Sbjct: 878 FTEPLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCD--NDKYRISRTGDTHTLK 935 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483 + + ++D+G TC+A + +G ++ V+ Sbjct: 936 LGPLAVADTGYYTCIASSPAGSARSTAKVTVL 967 Score = 41.9 bits (94), Expect = 0.012 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 2/100 (2%) Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 +FT Q++ V + + L K++ P V W N + + + +I T+TL + Sbjct: 877 TFTEPLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKL 936 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAE-CVVSLPATKDKP 4612 D+G Y C+A + AG AR A+ V+ +P KP Sbjct: 937 GPLAVADTGYYTCIASSPAGSARSTAKVTVLGVPEPPYKP 976 Score = 41.9 bits (94), Expect = 0.012 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481 FT PL +I + E +++ D P KV W WN L ++R L+ Sbjct: 878 FTEPLQDIA-VNNTEYTELTCKISSPDFP-YKVSWAWNDTPLCDNDKYRISRTGDTHTLK 935 Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514 + P D+G Y C A + G A +TA + V G Sbjct: 936 LGPLAVADTGYYTCIASSPAGSARSTAKVTVLG 968 Score = 41.5 bits (93), Expect = 0.016 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKP-TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784 PL+DI V + + +I+S P + W + + +++ G+ L +G Sbjct: 881 PLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLA 940 Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVV 4810 DTG +TC A++ AG ++AK+ V Sbjct: 941 VADTGYYTCIASSPAGSARSTAKVTV 966 Score = 40.7 bits (91), Expect = 0.028 Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 1/92 (1%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835 F L +I + C + S D K+ W +N+ PL +Y+ + +L + Sbjct: 878 FTEPLQDIAVNNTEYTELTCKIS-SPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKL 936 Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867 D+G YTC A++ GSA ++ + G Sbjct: 937 GPLAVADTGYYTCIASSPAGSARSTAKVTVLG 968 Score = 40.3 bits (90), Expect = 0.037 Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 1/87 (1%) Query: 493 FVERFSTLNVREGEPVVLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIP 551 F E + V E L + P +++W + P+ N + RI G TL + Sbjct: 878 FTEPLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKLG 937 Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578 +D +Y C A + AGS + A++ Sbjct: 938 PLAVADTGYYTCIASSPAGSARSTAKV 964 Score = 39.5 bits (88), Expect = 0.065 Identities = 22/74 (29%), Positives = 41/74 (55%), Gaps = 4/74 (5%) Query: 296 RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 +V+W N L +++K+ I T + TL++ +D+G+YT +A +P G ++ + V Sbjct: 907 KVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLAVADTGYYTCIASSPAGSARSTAKVTV 966 Query: 356 ----ESPTESYVQD 365 E P + YV+D Sbjct: 967 LGVPEPPYKPYVKD 980 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 1/92 (1%) Query: 3560 FTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEI 3619 FT D+ ++ C+ I D +V W N PL + + L++ Sbjct: 878 FTEPLQDIAVNNTEYTELTCK-ISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKL 936 Query: 3620 GGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651 G + D G YTC A++ G A + K+ V G Sbjct: 937 GPLAVADTGYYTCIASSPAGSARSTAKVTVLG 968 Score = 37.1 bits (82), Expect = 0.35 Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 1/106 (0%) Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357 TK E + + F+ L +I L C++ D +V W N P+ Sbjct: 863 TKNFEEPLEDDGSITFTEPLQDIAVNNTEYTELTCKISSP-DFPYKVSWAWNDTPLCDND 921 Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 ++R + D L L + D+G YTC A++ G A ++ + V+ Sbjct: 922 KYRISRTGDTHTLKLGPLAVADTGYYTCIASSPAGSARSTAKVTVL 967 Score = 36.3 bits (80), Expect = 0.61 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 2/90 (2%) Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALD 3756 FT ++D I V C++ P ++ W N P + L Sbjct: 878 FTEPLQD-IAVNNTEYTELTCKISSPDFP-YKVSWAWNDTPLCDNDKYRISRTGDTHTLK 935 Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKIT 3786 + + D G YTC A++ GSA +TAK+T Sbjct: 936 LGPLAVADTGYYTCIASSPAGSARSTAKVT 965 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 1/71 (1%) Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925 C+I PD +V W +N L +YR S L + + D+G YTC A + Sbjct: 897 CKISS-PDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLAVADTGYYTCIASSPA 955 Query: 1926 GQAVSSIRLNV 1936 G A S+ ++ V Sbjct: 956 GSARSTAKVTV 966 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/106 (21%), Positives = 46/106 (43%), Gaps = 5/106 (4%) Query: 1964 YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023 ++ ++DD + F +P+++ V L ++ + P +V W N P+ Sbjct: 866 FEEPLEDDGSIT----FTEPLQDIAVNNTEYTELTCKISSPDFP-YKVSWAWNDTPLCDN 920 Query: 2024 HRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 +++ + L + DTG Y C A++ G A +T+ V V Sbjct: 921 DKYRISRTGDTHTLKLGPLAVADTGYYTCIASSPAGSARSTAKVTV 966 Score = 33.5 bits (73), Expect = 4.3 Identities = 18/60 (30%), Positives = 28/60 (46%) Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 K+ W N L + + + TL + L D+G YTC A++ G A STA + + Sbjct: 907 KVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLAVADTGYYTCIASSPAGSARSTAKVTV 966 Score = 32.7 bits (71), Expect = 7.5 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 4/54 (7%) Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEA 155 VSW PL + +KY + +TGD +L + + D G YTC A + G A Sbjct: 908 VSWAWNDTPLCDNDKYRI---SRTGDTHTLKLGPLAVADTGYYTCIASSPAGSA 958 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 911 FKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALT 970 F P++D I++ + ++ D +V W + P+ + + L Sbjct: 878 FTEPLQD-IAVNNTEYTELTCKISS-PDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLK 935 Query: 971 IKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 + + V D G+YTC A + G A ++A +T++ Sbjct: 936 LGPLAVADTGYYTCIASSPAGSARSTAKVTVL 967 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 1/81 (1%) Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048 E T+ C+++ P KV W +N PL +++ + G + D+G Y C Sbjct: 891 EYTELTCKISSPDFP-YKVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLAVADTGYYTC 949 Query: 4049 RATNLYGMDETKAVIKTTGKP 4069 A++ G + A + G P Sbjct: 950 IASSPAGSARSTAKVTVLGVP 970 >SB_9202| Best HMM Match : ig (HMM E-Value=5e-40) Length = 1604 Score = 52.4 bits (120), Expect = 9e-06 Identities = 53/199 (26%), Positives = 87/199 (43%), Gaps = 19/199 (9%) Query: 4623 PEIIEPLKDKIVAEGQA-IEFSCKIVGKP-LPTVQWYKGDKL-IKP-----SKYFQMSRT 4674 P +IE ++ VA+ + +EF CK G+P + + W+KG + P SKYF + Sbjct: 333 PVVIELTANQSVAKSASFVEFFCKAEGEPAVSSYSWFKGQTTAVSPIANDNSKYFISDGS 392 Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734 E LR++ +D G Y C A NS G + + + +T A + +T + + V E Sbjct: 393 NGEKRLRVNTLLKDDAGWYTCAARNSRG-LGLGSSTYLTVL-YAPEVMDITFIPSVTVDE 450 Query: 4735 GQPAQFKTQITSKIKPTIQW--LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792 + P W E +I + D G + L++ ++D G +T Sbjct: 451 YDDVTLRCISDGGPIPFFTWRFKNENKVIQGSGD-----RGRD--LVVSRAKKDDAGNYT 503 Query: 4793 CRATTAAGQVETSAKLVVK 4811 C AT + G + S L VK Sbjct: 504 CVATNSQGVNQHSELLYVK 522 Score = 49.2 bits (112), Expect = 8e-05 Identities = 51/197 (25%), Positives = 79/197 (40%), Gaps = 18/197 (9%) Query: 392 PQFVKVCQDRDVTEG-KMTRFDCRVTGRP-YPEVTWFINDRQ----IRDDYNHKILVNE- 444 P +++ ++ V + F C+ G P +WF I +D N K +++ Sbjct: 333 PVVIELTANQSVAKSASFVEFFCKAEGEPAVSSYSWFKGQTTAVSPIAND-NSKYFISDG 391 Query: 445 -SGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502 +G L + + D+G TC ARN G L V+ +V+ F+ ++ V Sbjct: 392 SNGEKRLRVNTLLKDDAGWYTCAARNSRGLGLGSSTYLTVLYAPEVMDITFI---PSVTV 448 Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562 E + V L + G P P TW+ N ++ D G L + RAK DA Y Sbjct: 449 DEYDDVTLRCISDGGPIPFFTWRFKN----ENKVIQGSGDRGRD-LVVSRAKKDDAGNYT 503 Query: 563 CTAQNVAGSTATRARLY 579 C A N G LY Sbjct: 504 CVATNSQGVNQHSELLY 520 Score = 48.0 bits (109), Expect = 2e-04 Identities = 43/165 (26%), Positives = 70/165 (42%), Gaps = 17/165 (10%) Query: 381 ERIEISEKALAPQFVKVCQDRD--VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438 +RI I+ + + P FV D TE + + + C G+P P++ WF+N R + D Sbjct: 605 KRIRITVQ-VGPAFVTSLPPNDGIKTENETSNYTCTADGKPAPDILWFVNGRNVTVDSPE 663 Query: 439 KILVNESG-----NHALM----ITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQ 487 V G N L+ + +V S G ++CVARN +G L V + Sbjct: 664 LGRVTAQGSVSPANVKLIRVESVLHVMYSWLHDGNISCVARNPAGSVQQTTLLQV--RYC 721 Query: 488 VVAPKFVERFSTLNVREGEPVVLNARAVGTP-TPRITWQKDGVPI 531 V + + + + EG + R +G P T + W + V I Sbjct: 722 PVVKTYADHPKNVTLDEGGDATFSCRTIGNPVTDYVEWYFNEVKI 766 Score = 42.3 bits (95), Expect = 0.009 Identities = 43/186 (23%), Positives = 76/186 (40%), Gaps = 27/186 (14%) Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPT-VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688 K+ + EG FSC+ +G P+ V+WY + I S+ + +T R Sbjct: 732 KNVTLDEGGDATFSCRTIGNPVTDYVEWYFNEVKIPDSR-------GNSFTRR--NVGGR 782 Query: 4689 DEGDYKCVAYNS---AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQIT 4745 D G Y C +++ G A L + + P +T E A ++T Sbjct: 783 DAGLYSCRGFSTLCDRGGPLFGAHLFIKTGPRITFYPKVTRAN-----ETGSALLYCRVT 837 Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805 +P + W +EG + ++H G L+GN +D+G + C+A + + Sbjct: 838 GVPEPVVTWYKEG-------NATLLHTGKE--FLVGNLTYQDSGNYICQAVNSEATDRAT 888 Query: 4806 AKLVVK 4811 +LVV+ Sbjct: 889 LELVVQ 894 Score = 41.1 bits (92), Expect = 0.021 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 18/162 (11%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 CRVTG P P VTW+ + N +L +G ++ N+T DSG C A N Sbjct: 834 CRVTGVPEPVVTWY-------KEGNATLL--HTGKE-FLVGNLTYQDSGNYICQAVN--S 881 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK--DGVP 530 E + L ++ + V + + G+ + A P W + D +P Sbjct: 882 EATDRATLELVVQVVPVITTDKPTDTDIAGEAGKVSSIRCSARSEPPAEYWWTRGSDRIP 941 Query: 531 II-PNPELR-IHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 + +P +R I+ +G + TL I A + Y C A+N+ G Sbjct: 942 LTGSSPRVRSINDEGNSRTLMIEVASFGET--YYCHARNIMG 981 Score = 36.3 bits (80), Expect = 0.61 Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 24/183 (13%) Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696 G A+ + C++ G P P V WYK + T E+ + +D G+Y C Sbjct: 828 GSALLY-CRVTGVPEPVVTWYKEGNA-------TLLHTGKEFL--VGNLTYQDSGNYICQ 877 Query: 4697 AYNS--AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754 A NS R T+ ++V P + P T DI G+ + + S+ W Sbjct: 878 AVNSEATDRATLELVVQVV-PVITTDKPTDT---DIAGEAGKVSSIRCSARSEPPAEYWW 933 Query: 4755 LREGALIPET---PDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 R IP T P + I+ EGN+ L+I T+ C A G+ K V+ Sbjct: 934 TRGSDRIPLTGSSPRVRSINDEGNSRTLMI--EVASFGETYYCHARNIMGR--DIQKYVI 989 Query: 4811 KSK 4813 + K Sbjct: 990 REK 992 Score = 35.1 bits (77), Expect = 1.4 Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 5/127 (3%) Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHT-VEESEGVRFECRVEPKEDPKLR 3862 SG I + +D E +V P T + T + G R + +P Sbjct: 871 SGNYICQAVNSEATDRATLELVVQVVPVITTDKPTDTDIAGEAGKVSSIRCSARSEPPAE 930 Query: 3863 IEWYRNGKLLP---SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 W R +P S R R++ D G S ++ A Y C A N G D K I Sbjct: 931 YWWTRGSDRIPLTGSSPRVRSINDEGN-SRTLMIEVASFGETYYCHARNIMGRDIQKYVI 989 Query: 3920 SCKKLPD 3926 K PD Sbjct: 990 REKGPPD 996 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 14/72 (19%) Query: 3564 PSDLILSENSSAHFECRLI--PVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621 P ++ L E A F CR I PV D VEW+ N + + SR + F +GG Sbjct: 731 PKNVTLDEGGDATFSCRTIGNPVTDY---VEWYFN-EVKIPDSRGNS-----FTRRNVGG 781 Query: 3622 VYQRDAGLYTCK 3633 RDAGLY+C+ Sbjct: 782 ---RDAGLYSCR 790 Score = 34.7 bits (76), Expect = 1.9 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 16/108 (14%) Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK--VLQSGHRYRTSN 1897 + PR IT T+ +E SA CR+ P+P V WY G +L +G + N Sbjct: 809 IKTGPR-ITFYPKVTRANETGSALLYCRVTGVPEPV--VTWYKEGNATLLHTGKEFLVGN 865 Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945 LT +DSG Y C+A+N+ +++ L VQ I D Sbjct: 866 ---------LTY--QDSGNYICQAVNSEATDRATLELVVQVVPVITTD 902 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 9/77 (11%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P+I P+ ++ E A +++G P P VTW+K G + H V Sbjct: 813 PRITFYPKVTRANETGSALLYCRVTGVPEPVVTWYKEGNATL---------LHTGKEFLV 863 Query: 326 RNTQKSDSGHYTLLAEN 342 N DSG+Y A N Sbjct: 864 GNLTYQDSGNYICQAVN 880 Score = 34.3 bits (75), Expect = 2.5 Identities = 35/157 (22%), Positives = 58/157 (36%), Gaps = 9/157 (5%) Query: 1067 VEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGE 1126 V Q + T +W F+ S ++ Q YVA +IA+ E+ V A N G Sbjct: 228 VYAQEGTSYTFDWRFSSTSTRSFSQWQVTKPPNYVATNIATKTGENGPVQVASAYN--GR 285 Query: 1127 AQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNP 1186 + V R + G Y H + F+ + + KPV ++ +N Sbjct: 286 VTFESGNQVGFRLD-SLQAADNGRYMCNLHFADGGFLTDTANL--VVVDKPVVIELTANQ 342 Query: 1187 PPVSEGKNIHLECRLEPMGDPTM-RVEWFHNGRSVTV 1222 + C+ E G+P + WF G++ V Sbjct: 343 SVAKSASFVEFFCKAE--GEPAVSSYSWF-KGQTTAV 376 Score = 34.3 bits (75), Expect = 2.5 Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 19/128 (14%) Query: 405 EGKMTRFDCRVTGRPYPE-VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV 463 EG F CR G P + V W+ N+ +I D S ++ NV D+G+ Sbjct: 738 EGGDATFSCRTIGNPVTDYVEWYFNEVKIPD----------SRGNSFTRRNVGGRDAGLY 787 Query: 464 TCVARNK---SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520 +C + G F L + ++ F + + N E +L R G P P Sbjct: 788 SCRGFSTLCDRGGPLFGAHLFIKTGPRIT---FYPKVTRAN--ETGSALLYCRVTGVPEP 842 Query: 521 RITWQKDG 528 +TW K+G Sbjct: 843 VVTWYKEG 850 Score = 33.9 bits (74), Expect = 3.2 Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 11/88 (12%) Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595 +VTG V W K G + L + TY QDSG Y C A+NS Sbjct: 835 RVTGVPEPVVTWYKEGNATLLHTGKEFLVGNLTY---------QDSGNYICQAVNSEATD 885 Query: 4596 RCDAECVVS-LPA-TKDKPKPQTKAANA 4621 R E VV +P T DKP A A Sbjct: 886 RATLELVVQVVPVITTDKPTDTDIAGEA 913 Score = 33.1 bits (72), Expect = 5.7 Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 4111 PVFV-SLPDAVTVE-EGEWARFCCRVTGHPKPRVMWLLNGNTI 4151 P FV SLP ++ E E + + C G P P ++W +NG + Sbjct: 615 PAFVTSLPPNDGIKTENETSNYTCTADGKPAPDILWFVNGRNV 657 Score = 33.1 bits (72), Expect = 5.7 Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 12/71 (16%) Query: 2388 IQEGQTAHFDCRLIPVGDP-TLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446 + EG A F CR I G+P T VEW+ NE I DS S T +V D Sbjct: 736 LDEGGDATFSCRTI--GNPVTDYVEWYFNEVKIPDSRGN---------SFTRRNVGGRDA 784 Query: 2447 GVYMCRASNLL 2457 G+Y CR + L Sbjct: 785 GLYSCRGFSTL 795 Score = 32.7 bits (71), Expect = 7.5 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 9/102 (8%) Query: 263 VSPPKIAQKPRNSKLQEGAD-AQFQVQLSGNPR-PRVTWFKNGQRLI----NSNKHEIIT 316 V P + + N + + A +F + G P +WFK + N N I+ Sbjct: 330 VDKPVVIELTANQSVAKSASFVEFFCKAEGEPAVSSYSWFKGQTTAVSPIANDNSKYFIS 389 Query: 317 --THNHTTLRVRNTQKSDSGHYTLLAENPNGC-IVTSGYLAV 355 ++ LRV K D+G YT A N G + +S YL V Sbjct: 390 DGSNGEKRLRVNTLLKDDAGWYTCAARNSRGLGLGSSTYLTV 431 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 14/91 (15%) Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208 PR T + + + G SA C V V +P + WY G ++T + T +F +V Sbjct: 813 PRITFYPKVTRANETG-SALLYCRVTGVPEP--VVTWYKEG----NATLLHTGKEF--LV 863 Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239 ++ Y DSG Y+C+A N D RAT+ Sbjct: 864 GNLTY---QDSGNYICQAVNSEATD--RATL 889 >SB_45516| Best HMM Match : I-set (HMM E-Value=1.1e-26) Length = 939 Score = 52.0 bits (119), Expect = 1e-05 Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%) Query: 392 PQFVKVCQDRDVTEG-KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 PQ ++ +D +V EG + T C+ G P P++TW + R D +IL S Sbjct: 329 PQIIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWL---KLSRPD---QIL---SKGETF 379 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQ-CRLNVIEKEQVVAPKFVERFSTLNVREGE 506 IT+VT D G+ C+ARN G A + +NV + VAP+ E N EGE Sbjct: 380 FITSVTREDHGLYRCMARNNVGAAAIKDFTINVRYRFHDVAPQIGETQLFNNADEGE 436 Score = 51.2 bits (117), Expect = 2e-05 Identities = 72/280 (25%), Positives = 99/280 (35%), Gaps = 36/280 (12%) Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 V G++ +L K TG V W K+GK+V R K E + D Sbjct: 156 VQYKEGEVKKLVCKATGKPNPWVIWYKDGKEVMK--RKKRAE------IAFDPVTDADMA 207 Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642 Y+CVA NS G+ V KPK T +A V+ G + F Sbjct: 208 SYKCVAQNSGGKEERVTNVTVMF-----KPKETTLRTDA--------NGNTVSVGSTVSF 254 Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 C G P PT ++Y + P + + + G Y C+ NS G Sbjct: 255 FCAARGYPKPTYKFYIKARGQPPRRLDYRDAELTGHIKNLGVVDSRWHGTYICIPSNSVG 314 Query: 4703 R-VTVAAKLKVTQPDQADNLPALTPLRDIVVYEG-QPAQFKTQITSKIKPTIQWLREGAL 4760 L V P Q + P RD+ V EG Q + Q P I WL+ Sbjct: 315 EGPRQELLLYVRYPPQ-----IIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWLK---- 365 Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 PD Q++ +G I + ED G + C A G Sbjct: 366 -LSRPD-QILSKGE--TFFITSVTREDHGLYRCMARNNVG 401 Score = 48.4 bits (110), Expect = 1e-04 Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 16/123 (13%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--STLNVREGEP 507 L ITNV LSD G C R + ++N+I V+AP ++ +T+ +EGE Sbjct: 110 LEITNVQLSDEGNYVCELRTLF--MMIKAKINLI----VIAPAKIKSSPPATVQYKEGEV 163 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 L +A G P P + W KDG ++ + + + +D A Y+C AQN Sbjct: 164 KKLVCKATGKPNPWVIWYKDGKEVMKRKK--------RAEIAFDPVTDADMASYKCVAQN 215 Query: 568 VAG 570 G Sbjct: 216 SGG 218 Score = 46.4 bits (105), Expect = 6e-04 Identities = 67/287 (23%), Positives = 106/287 (36%), Gaps = 45/287 (15%) Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483 E E + + G+P P + WY++ + ++ + V D A + Sbjct: 160 EGEVKKLVCKATGKPNPWVIWYKDGKEVMKR--------KKRAEIAFDPVTDADMASYKC 211 Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG-TKP 4542 VA+N GG + N+ V K ++ + A V+ G V G KP Sbjct: 212 VAQNSGGKEERVTNVTVMFKPKE-------TTLRTDANGNTVSVGSTVSFFCAARGYPKP 264 Query: 4543 IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD-SGKYECVAINSAGEARCDAEC 4601 +++K + QP R + + T + L G Y C+ NS GE Sbjct: 265 TYKFYIK--ARGQPPRRLDYRDAELTGHIKNLGVVDSRWHGTYICIPSNSVGEG------ 316 Query: 4602 VVSLPATKDKPKPQTKA-ANAPPEIIEPLKDKIVAEG-QAIEFSCKIVGKPLPTVQWYKG 4659 P+ + PP+II P +D V EG Q C+ G P P + W K Sbjct: 317 ----------PRQELLLYVRYPPQIIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWLK- 365 Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706 L +P + T I+ ED G Y+C+A N+ G + Sbjct: 366 --LSRPDQILSKGET-----FFITSVTREDHGLYRCMARNNVGAAAI 405 Score = 44.8 bits (101), Expect = 0.002 Identities = 60/251 (23%), Positives = 91/251 (36%), Gaps = 28/251 (11%) Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611 K V P +I +D TL I D G Y C + +V PA Sbjct: 92 KSVPPSFLGRIRIKDRA-TLEITNVQLSDEGNYVCELRTLFMMIKAKINLIVIAPA---- 146 Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671 K ++PP ++ EG+ + CK GKP P V WYK K + K Sbjct: 147 -----KIKSSPPATVQ------YKEGEVKKLVCKATGKPNPWVIWYKDGKEVMKRK---- 191 Query: 4672 SRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731 + A+ +++A D YKCVA NS G+ + V + L T Sbjct: 192 -KRAEIAFDPVTDA---DMASYKCVAQNSGGKEERVTNVTVMFKPKETTL--RTDANGNT 245 Query: 4732 VYEGQPAQFKTQITSKIKPTIQ-WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790 V G F KPT + +++ P D++ E + +G GT Sbjct: 246 VSVGSTVSFFCAARGYPKPTYKFYIKARGQPPRRLDYRDA-ELTGHIKNLGVVDSRWHGT 304 Query: 4791 FTCRATTAAGQ 4801 + C + + G+ Sbjct: 305 YICIPSNSVGE 315 Score = 43.6 bits (98), Expect = 0.004 Identities = 49/180 (27%), Positives = 73/180 (40%), Gaps = 26/180 (14%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDR---QIRDDYNHKILVNESGNHALMITNVTLSD 459 V+ G F C G P P ++I R R DY L I N+ + D Sbjct: 246 VSVGSTVSFFCAARGYPKPTYKFYIKARGQPPRRLDYRDAELTGH-------IKNLGVVD 298 Query: 460 S---GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP-VVLNARAV 515 S G C+ N GE Q L + P+ + +NV EG+ ++ +A Sbjct: 299 SRWHGTYICIPSNSVGEGPRQELLLYVR----YPPQIIRPPRDMNVDEGDQKTIVQCQAD 354 Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575 G P+P+ITW K + P+ +I + G T I D Y+C A+N G+ A + Sbjct: 355 GYPSPQITWLK-----LSRPD-QILSKG--ETFFITSVTREDHGLYRCMARNNVGAAAIK 406 Score = 36.3 bits (80), Expect = 0.61 Identities = 43/194 (22%), Positives = 73/194 (37%), Gaps = 19/194 (9%) Query: 382 RIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439 + +I+ +AP +K V EG++ + C+ TG+P P V W+ + +++ Sbjct: 135 KAKINLIVIAPAKIKSSPPATVQYKEGEVKKLVCKATGKPNPWVIWYKDGKEV------- 187 Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499 + + VT +D CVA+N G+ + V+ K + + +T Sbjct: 188 --MKRKKRAEIAFDPVTDADMASYKCVAQNSGGKEERVTNVTVMFKPKETTLRTDANGNT 245 Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559 ++V G V A G P P K + P R+ T I D+ Sbjct: 246 VSV--GSTVSFFCAARGYPKPT---YKFYIKARGQPPRRLDYRDAELTGHIKNLGVVDSR 300 Query: 560 W---YQCTAQNVAG 570 W Y C N G Sbjct: 301 WHGTYICIPSNSVG 314 Score = 36.3 bits (80), Expect = 0.61 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 1/56 (1%) Query: 4115 SLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIV-NGSRYKLTYDGMYHFDI 4169 S P V +EGE + C+ TG P P V+W +G ++ R ++ +D + D+ Sbjct: 151 SPPATVQYKEGEVKKLVCKATGKPNPWVIWYKDGKEVMKRKKRAEIAFDPVTDADM 206 Score = 36.3 bits (80), Expect = 0.61 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Query: 265 PPKIAQKPRNSKLQEGADAQF-QVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323 PP+I + PR+ + EG Q Q G P P++TW K S +I++ T Sbjct: 328 PPQIIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWLK------LSRPDQILS--KGETF 379 Query: 324 RVRNTQKSDSGHYTLLAENPNG 345 + + + D G Y +A N G Sbjct: 380 FITSVTREDHGLYRCMARNNVG 401 Score = 34.7 bits (76), Expect = 1.9 Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 13/112 (11%) Query: 4046 YLCRATNLYGMDETKAVIKTTGKPG--IVY-DSQLPKHMKSIEKI-REMEASWQVTPEQV 4101 + C A Y K IK G+P + Y D++L H+K++ + ++ P Sbjct: 254 FFCAARG-YPKPTYKFYIKARGQPPRRLDYRDAELTGHIKNLGVVDSRWHGTYICIPSNS 312 Query: 4102 VEESK-------ARCPPVFVSLPDAVTVEEGEWARFC-CRVTGHPKPRVMWL 4145 V E R PP + P + V+EG+ C+ G+P P++ WL Sbjct: 313 VGEGPRQELLLYVRYPPQIIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWL 364 Score = 33.5 bits (73), Expect = 4.3 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 10/85 (11%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P+ P +D +++ EG + + G + ++ WLK RP + S+ TFF Sbjct: 329 PQIIRPPRD-MNVDEGDQKTI-VQCQADGYPSPQITWLKLSRPDQILSKGETFF------ 380 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQA 993 I SVT D G Y C A N +G A Sbjct: 381 --ITSVTREDHGLYRCMARNNVGAA 403 Score = 32.7 bits (71), Expect = 7.5 Identities = 14/50 (28%), Positives = 27/50 (54%), Gaps = 1/50 (2%) Query: 263 VSPPKI-AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311 ++P KI + P + +EG + + +G P P V W+K+G+ ++ K Sbjct: 143 IAPAKIKSSPPATVQYKEGEVKKLVCKATGKPNPWVIWYKDGKEVMKRKK 192 >SB_43869| Best HMM Match : ig (HMM E-Value=2.7e-06) Length = 399 Score = 52.0 bits (119), Expect = 1e-05 Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 9/148 (6%) Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 I C GKP PTV W K K ++S +Y LR+ D G Y C N Sbjct: 135 INLDCSADGKPRPTVVWLKNGKPFFKRDGVELSLRPYQYVLRLRGVVSSDNGQYTCNVSN 194 Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL---- 4755 S ++ + V + + + L + P ++ G K S P +WL Sbjct: 195 SCDWISRTFTVHVKKREPSKPLIQIIP--NVTARNGDNVTLKCNAMSDSMPRFRWLILTS 252 Query: 4756 --REGALIPETPD-FQMIHEGNNAVLLI 4780 LI ETP+ +++I + +A ++ Sbjct: 253 PQNASTLINETPNHYKVIKQSRHADYIV 280 Score = 41.5 bits (93), Expect = 0.016 Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 7/115 (6%) Query: 412 DCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469 DC G+P P V W N + RD L + L + V SD+G TC N Sbjct: 138 DCSADGKPRPTVVWLKNGKPFFKRDGVE---LSLRPYQYVLRLRGVVSSDNGQYTCNVSN 194 Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524 + ++V ++E + ++ + R G+ V L A+ PR W Sbjct: 195 SCDWISRTFTVHVKKREP--SKPLIQIIPNVTARNGDNVTLKCNAMSDSMPRFRW 247 Score = 40.7 bits (91), Expect = 0.028 Identities = 19/52 (36%), Positives = 24/52 (46%) Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342 G PRP V W KNG+ + E+ LR+R SD+G YT N Sbjct: 143 GKPRPTVVWLKNGKPFFKRDGVELSLRPYQYVLRLRGVVSSDNGQYTCNVSN 194 Score = 40.3 bits (90), Expect = 0.037 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 6/81 (7%) Query: 3708 PEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH-TLNDFGFIALDIDYIYARDAG 3766 P+ ++ DC + G P + W NG+PF V +L + ++ L + + + D G Sbjct: 130 PDRAIINLDCSAD--GKPRPTVVWLKNGKPFFKRDGVELSLRPYQYV-LRLRGVVSSDNG 186 Query: 3767 EYTCRATNK--WGSATTTAKI 3785 +YTC +N W S T T + Sbjct: 187 QYTCNVSNSCDWISRTFTVHV 207 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 2/69 (2%) Query: 1738 GDPKLRVEWLRNGVPIEASNRL-TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796 G P+ V WL+NG P + + ++ + YV L ++ V D+G YTC N Sbjct: 143 GKPRPTVVWLKNGKPFFKRDGVELSLRPYQYV-LRLRGVVSSDNGQYTCNVSNSCDWISR 201 Query: 1797 SSTLFVQSK 1805 + T+ V+ + Sbjct: 202 TFTVHVKKR 210 Score = 33.9 bits (74), Expect = 3.2 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 3591 VEWFHNGKPLLTGSRVK-TINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 V W NGKP V+ ++ + +V L + GV D G YTC +N + + + V Sbjct: 149 VVWLKNGKPFFKRDGVELSLRPYQYV-LRLRGVVSSDNGQYTCNVSNSCDWISRTFTVHV 207 Query: 3650 KGRQ 3653 K R+ Sbjct: 208 KKRE 211 >SB_9034| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1756 Score = 52.0 bits (119), Expect = 1e-05 Identities = 35/138 (25%), Positives = 58/138 (42%), Gaps = 13/138 (9%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 P I P ++ + G ++ +C G P+PT+ W KG ++I + F + + Sbjct: 769 PTTAINPDAERTLNIGDNLQLNCSATGCPIPTLTWLKGSQIIDRGRGFAL-------PIN 821 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY-EGQPAQF 4740 I A DEG+Y+C+A N +++V +P +T + + EG A Sbjct: 822 ILNAQLSDEGEYRCIADNGVSGGHPRQQIRVVV-----RIPVITSEQSSHSFNEGDQASL 876 Query: 4741 KTQITSKIKPTIQWLREG 4758 T P I W R G Sbjct: 877 YCNATGYPTPNINWTRLG 894 Score = 47.6 bits (108), Expect = 2e-04 Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 12/129 (9%) Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 +R + G + +C TG P P +TW + I + +N I N LSD Sbjct: 778 ERTLNIGDNLQLNCSATGCPIPTLTWLKGSQIIDRGRGFALPIN--------ILNAQLSD 829 Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519 G C+A N + ++ V+ V P S+ + EG+ L A G PT Sbjct: 830 EGEYRCIADNGVSGGHPRQQIRVV----VRIPVITSEQSSHSFNEGDQASLYCNATGYPT 885 Query: 520 PRITWQKDG 528 P I W + G Sbjct: 886 PNINWTRLG 894 Score = 41.5 bits (93), Expect = 0.016 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517 S S V+ C A+NK+G +N IE E + P + S+L G L+ A G Sbjct: 44 SGSNVLRCDAQNKAGSDTET--INSIEIEGI--PVITSKQSSLTFNNGGQAFLHCNATGY 99 Query: 518 PTPRITWQKDG 528 PTP +TW + G Sbjct: 100 PTPNVTWIRLG 110 Score = 40.3 bits (90), Expect = 0.037 Identities = 39/116 (33%), Positives = 48/116 (41%), Gaps = 18/116 (15%) Query: 410 RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV--VTCVA 467 R C T +P F D N +I SGN IT VTLS G TCV Sbjct: 353 RLSCISTSKPAATKFTFYKD-------NVEIANTSSGN----IT-VTLSTQGTHQFTCVP 400 Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523 N +G T + V+ K P + ++L EGE LN A G PTP +T Sbjct: 401 ENVAG-TGENATVTVLVKG---VPVITSKKTSLTFNEGESATLNCNATGYPTPEVT 452 Score = 39.1 bits (87), Expect = 0.086 Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 1/67 (1%) Query: 4083 SIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRV 4142 SIE I E +V E + K PV S ++T EG+ A F C TG P P V Sbjct: 221 SIE-IEGKERKSKVRKENRRQGKKIEGIPVITSKLSSLTFNEGDQASFHCNATGFPTPNV 279 Query: 4143 MWLLNGN 4149 W+ G+ Sbjct: 280 TWIRLGD 286 Score = 37.1 bits (82), Expect = 0.35 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 9/96 (9%) Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251 G N+ L C G P + W + + G F + ++I++A +D GEY Sbjct: 784 GDNLQLNC--SATGCPIPTLTWLKGSQIIDRGRGFA-------LPINILNAQLSDEGEYR 834 Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQ 1287 A N + H +RV+ R ++T Q+ + + Sbjct: 835 CIADNGVSGGHPRQQIRVVVRIPVITSEQSSHSFNE 870 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 8/79 (10%) Query: 265 PPKIAQKPRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323 PP A P + L G + Q +G P P +TW K G ++I+ + + + Sbjct: 768 PPTTAINPDAERTLNIGDNLQLNCSATGCPIPTLTWLK-GSQIIDRGRGFAL------PI 820 Query: 324 RVRNTQKSDSGHYTLLAEN 342 + N Q SD G Y +A+N Sbjct: 821 NILNAQLSDEGEYRCIADN 839 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 10/84 (11%) Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765 + T + P + N+ + F G P + + W R+G P+ Sbjct: 581 IATVTVLVKAPFTASQFTVNETSDFSLHCDVTGSPPVSITWSRHGEPLLVQGAW------ 634 Query: 1766 GYVALNMKYVNPEDSGTYTCRAIN 1789 LNM V P G YTCRA N Sbjct: 635 ----LNMTSVTPVHEGVYTCRADN 654 Score = 33.9 bits (74), Expect = 3.2 Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 23/140 (16%) Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570 +V FT + VN TS + D VTG+ P+ + W ++G+ L G + Sbjct: 587 LVKAPFTASQFTVNETSDFSLHCD--VTGSPPVSITWSRHGEP---------LLVQGAW- 634 Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 L + P G Y C A N G+ E V + A KP+ T NA Sbjct: 635 LNMTSVTPVHEGVYTCRADN--GDECASHERSVQI-AVNFKPRNTTLLTNA--------S 683 Query: 4631 DKIVAEGQAIEFSCKIVGKP 4650 D V +G+++ SC+ KP Sbjct: 684 DVTVLQGKSLALSCESRAKP 703 Score = 33.5 bits (73), Expect = 4.3 Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528 P + S+L EG+ + A G PTP +TW + G Sbjct: 248 PVITSKLSSLTFNEGDQASFHCNATGFPTPNVTWIRLG 285 Score = 32.7 bits (71), Expect = 7.5 Identities = 14/39 (35%), Positives = 19/39 (48%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149 PV S ++T G A C TG+P P V W+ G+ Sbjct: 73 PVITSKQSSLTFNNGGQAFLHCNATGYPTPNVTWIRLGD 111 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 13/83 (15%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V + + +C +T P P VTWF D ++ GN + ++ T + SGV Sbjct: 995 VRKNETVTLEC-ITSLPSPHVTWF--------DVQGVVI----GNQSSLVFVATNTSSGV 1041 Query: 463 VTCVARNKSGETAFQCRLNVIEK 485 TC R+ +G T + ++++ Sbjct: 1042 YTCAVRSTAGRTVNSSAVVLVQR 1064 >SB_3465| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 477 Score = 51.2 bits (117), Expect = 2e-05 Identities = 53/185 (28%), Positives = 78/185 (42%), Gaps = 28/185 (15%) Query: 392 PQFVKVCQDRDVTEGKMT-RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450 P + D+ V E + + C G P P VTW RD ++ S H+ Sbjct: 3 PSILSKSPDQTVNETTGSLKLTCISDGYPSPTVTWS------RDGV---VVSRTSVYHS- 52 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 +VT S++G TC A N G ++ V K ++V+ ST+N + VL Sbjct: 53 --NSVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVS-------STINTSSWDRKVL 103 Query: 511 N--ARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQ 566 + +A G P P+ITW G PI + G S L + + A D Y+C A Sbjct: 104 SLQCKARGVPLPQITWYNPGGQPITAG----VSPISGGSQLQVTTTQDAGDYGQYKCRAS 159 Query: 567 NVAGS 571 N+ GS Sbjct: 160 NLLGS 164 Score = 39.5 bits (88), Expect = 0.065 Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 14/118 (11%) Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175 +++GTY+C ATN G +V++ + KP + N D + +C Sbjct: 58 SEAGTYTCTATNAMGSDTTTVQV-----TVNYKPEMVSSTINTSSW-DRKVLSLQCKARG 111 Query: 3176 VDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231 V P +I WY+ GQP+ + + +S G L + TQ+ D G+Y CRA N G Sbjct: 112 VPLP--QITWYNPGGQPI--TAGVSPIS--GGSQLQVTTTQDAGDYGQYKCRASNLLG 163 Score = 37.9 bits (84), Expect = 0.20 Identities = 16/31 (51%), Positives = 22/31 (70%) Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794 +AG YTC ATN GS TTT ++T + K ++V Sbjct: 59 EAGTYTCTATNAMGSDTTTVQVTVNYKPEMV 89 Score = 37.5 bits (83), Expect = 0.26 Identities = 16/39 (41%), Positives = 26/39 (66%) Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011 SVT +AG YTC A NA+G TT+ +T+ K ++++ + Sbjct: 54 SVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSST 92 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL-KKIQELEKYERPKPIEE-- 2102 + GTY C ATNA+G TT V V+ K + T++ +K+ L+ R P+ + Sbjct: 59 EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTINTSSWDRKVLSLQCKARGVPLPQIT 118 Query: 2103 -EQPGQRPV 2110 PG +P+ Sbjct: 119 WYNPGGQPI 127 Score = 37.1 bits (82), Expect = 0.35 Identities = 14/48 (29%), Positives = 27/48 (56%) Query: 2705 NSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDR 2752 NS+ ++G YTC ATN +G +T + + + ++ +++ S DR Sbjct: 53 NSVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTINTSSWDR 100 Score = 35.9 bits (79), Expect = 0.80 Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 21/183 (11%) Query: 4623 PEIIEPLKDKIVAEGQ-AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 P I+ D+ V E +++ +C G P PTV W + D ++ +SRT+ ++ Sbjct: 3 PSILSKSPDQTVNETTGSLKLTCISDGYPSPTVTWSR-DGVV-------VSRTSVYHSNS 54 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741 ++ + + G Y C A N+ G T ++ V + + T D V + Sbjct: 55 VTRS---EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTINTSSWDRKV-----LSLQ 106 Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE-DTGTFTCRATTAAG 4800 + P I W G P T I G+ L + T + D G + CRA+ G Sbjct: 107 CKARGVPLPQITWYNPGGQ-PITAGVSPISGGSQ--LQVTTTQDAGDYGQYKCRASNLLG 163 Query: 4801 QVE 4803 VE Sbjct: 164 SVE 166 Score = 33.5 bits (73), Expect = 4.3 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 11/64 (17%) Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809 PT+ W R+G ++ T ++ N+ + GT+TC AT A G T+ ++ Sbjct: 33 PTVTWSRDGVVVSRTS----VYHSNSVT-------RSEAGTYTCTATNAMGSDTTTVQVT 81 Query: 4810 VKSK 4813 V K Sbjct: 82 VNYK 85 Score = 32.7 bits (71), Expect = 7.5 Identities = 13/42 (30%), Positives = 25/42 (59%) Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQ 1554 ++G YTC A N +G+D + ++T ++V ST N + ++ Sbjct: 59 EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTINTSSWDR 100 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/85 (25%), Positives = 33/85 (38%), Gaps = 2/85 (2%) Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679 N PE++ + + + + CK G PLP + WY + +S + Sbjct: 83 NYKPEMVSSTINTSSWDRKVLSLQCKARGVPLPQITWYNPGGQPITAGVSPISGGSQLQV 142 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRV 4704 +A D G YKC A N G V Sbjct: 143 TTTQDA--GDYGQYKCRASNLLGSV 165 >SB_22798| Best HMM Match : Cadherin (HMM E-Value=0) Length = 3255 Score = 51.2 bits (117), Expect = 2e-05 Identities = 49/199 (24%), Positives = 78/199 (39%), Gaps = 28/199 (14%) Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLIL 4574 SF + ++ V +G L G W++NG + Y +I Sbjct: 2323 SFDVPPRSGTVVAGNPWTLKCSAKGNTSPQYRWMRNGLYLNS------FSNQSDY--VIA 2374 Query: 4575 EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV 4634 +A +D+G Y C+A + AG + A ++ N PEI +D V Sbjct: 2375 KATREDAGVYACLATSEAGLIQSSAATLI---------------VNVKPEITHHPEDSSV 2419 Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694 G C+ G P P+ +W+K +++I Q +D L + + +DE Y Sbjct: 2420 ELGGTATLECRASGVPEPSYRWFKNNEVIPSVGGIQ----SDRPVLVLRDVIAQDESPYY 2475 Query: 4695 CVAYNSAGRV-TVAAKLKV 4712 C A N AG + A LKV Sbjct: 2476 CQASNDAGTAKSNIATLKV 2494 Score = 45.6 bits (103), Expect = 0.001 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 13/138 (9%) Query: 4459 IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL 4518 +++FS +S +I + ED+ V+A +A + G + SA ++ V P T Sbjct: 2362 LNSFSNQSDYVIAKATREDAGVYACLATSEAGLIQSSAATLIVN---------VKPEITH 2412 Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP 4578 ++ +V G L+ + +G W KN +V P + ++ D L++ + Sbjct: 2413 HPEDSSVELGGTATLECRASGVPEPSYRWFKN-NEVIPSVGG--IQSDRP-VLVLRDVIA 2468 Query: 4579 QDSGKYECVAINSAGEAR 4596 QD Y C A N AG A+ Sbjct: 2469 QDESPYYCQASNDAGTAK 2486 Score = 44.8 bits (101), Expect = 0.002 Identities = 40/179 (22%), Positives = 71/179 (39%), Gaps = 18/179 (10%) Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687 P + V G C G P +W + Y +Y I++A Sbjct: 2327 PPRSGTVVAGNPWTLKCSAKGNTSPQYRWMRN------GLYLNSFSNQSDYV--IAKATR 2378 Query: 4688 EDEGDYKCVAYNSAGRV-TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746 ED G Y C+A + AG + + AA L V + + P D V G A + + + Sbjct: 2379 EDAGVYACLATSEAGLIQSSAATLIVNVKPEITHHP-----EDSSVELGGTATLECRASG 2433 Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805 +P+ +W + +IP Q + VL++ + +D + C+A+ AG +++ Sbjct: 2434 VPEPSYRWFKNNEVIPSVGGIQ----SDRPVLVLRDVIAQDESPYYCQASNDAGTAKSN 2488 Score = 41.9 bits (94), Expect = 0.012 Identities = 42/169 (24%), Positives = 60/169 (35%), Gaps = 17/169 (10%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V G C G P+ W N + N V I T D+GV Sbjct: 2333 VVAGNPWTLKCSAKGNTSPQYRWMRNGLYLNSFSNQSDYV---------IAKATREDAGV 2383 Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522 C+A +++G ++ V P+ +V G L RA G P P Sbjct: 2384 YACLATSEAGLIQSSAATLIVN----VKPEITHHPEDSSVELGGTATLECRASGVPEPSY 2439 Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 W K+ +IP+ I +D L + A D + Y C A N AG+ Sbjct: 2440 RWFKNN-EVIPSVG-GIQSD--RPVLVLRDVIAQDESPYYCQASNDAGT 2484 Score = 40.7 bits (91), Expect = 0.028 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 8/105 (7%) Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899 VN P IT + + G +A ECR P+P+ R W+ N +V+ S ++ Sbjct: 2404 VNVKPE-ITHHPEDSSVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDR-- 2458 Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSI-RLNVQSKESII 1943 L + V +D Y C+A N+ G A S+I L V ES++ Sbjct: 2459 --PVLVLRDVIAQDESPYYCQASNDAGTAKSNIATLKVYGGESLV 2501 Score = 40.3 bits (90), Expect = 0.037 Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 12/128 (9%) Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176 D+G Y+C AT++ G + S V+ KP T H ++ ++ G +A EC V Sbjct: 2380 DAGVYACLATSEAGLIQSSAATLIVN----VKPEITHHPED-SSVELGGTATLECRASGV 2434 Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236 +P + W+ N + + I+ SD +VL Q D Y C+A N G + Sbjct: 2435 PEPSYR--WFKNNEVIPSVGGIQ--SDRPVLVLRDVIAQ--DESPYYCQASNDAGTAKSN 2488 Query: 3237 -ATINCYG 3243 AT+ YG Sbjct: 2489 IATLKVYG 2496 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 8/85 (9%) Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785 P R V G P K P +W+R G + N + +I Sbjct: 2327 PPRSGTVVAGNPWTLKCSAKGNTSPQYRWMRNGLYLNSF--------SNQSDYVIAKATR 2378 Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810 ED G + C AT+ AG +++SA ++ Sbjct: 2379 EDAGVYACLATSEAGLIQSSAATLI 2403 Score = 37.9 bits (84), Expect = 0.20 Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 11/129 (8%) Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183 G A ECR + +P + WF N + I + ++ V D++ A+D Y Sbjct: 2422 GGTATLECRASGVPEP--SYRWFKNNEVIPSVGGIQSDRPV-LVLRDVI---AQDESPYY 2475 Query: 2184 CKATNKLGEA-VNTCTLKVAGHRNII---LDTQHPNGLEKIRQLEAQG-HSTRIEVEEPK 2238 C+A+N G A N TLKV G +++ + + N +K + Q + ++ E K Sbjct: 2476 CQASNDAGTAKSNIATLKVYGGESLVALEVSVSNSNRAKKCNIFDIQAFKAALVKAIEAK 2535 Query: 2239 ISPPRFVTE 2247 ++ + E Sbjct: 2536 VTIANYTAE 2544 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 6/87 (6%) Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884 IV+ P+ + +VE ECR +P R W++N +++PS ++ + Sbjct: 2403 IVNVKPEITHHPEDSSVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDRPV 2460 Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911 V D++ A+D Y C+A ND G Sbjct: 2461 -LVLRDVI---AQDESPYYCQASNDAG 2483 Score = 37.1 bits (82), Expect = 0.35 Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Query: 4428 ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAEN 4487 A E G P P +W++ N I + Q S + +L++R V +D + + A N Sbjct: 2425 ATLECRASGVPEPSYRWFKNNEVIPSVGGIQ----SDRPVLVLRDVIAQDESPYYCQASN 2480 Query: 4488 RGGTAK 4493 GTAK Sbjct: 2481 DAGTAK 2486 Score = 36.3 bits (80), Expect = 0.61 Identities = 14/39 (35%), Positives = 21/39 (53%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304 P+I P +S ++ G A + + SG P P WFKN + Sbjct: 2408 PEITHHPEDSSVELGGTATLECRASGVPEPSYRWFKNNE 2446 Score = 35.9 bits (79), Expect = 0.80 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 7/100 (7%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 PE T P D + +A ECR V + S R WF N + + + +++ +L Sbjct: 2408 PEITHHPEDSSVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDRP----VL 2461 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVS-CKLQVKGRQGII 3656 + V +D Y C+A+N G A + L+V G + ++ Sbjct: 2462 VLRDVIAQDESPYYCQASNDAGTAKSNIATLKVYGGESLV 2501 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 6/72 (8%) Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446 +++ G TA +CR V +P+ + WF+N ++I I + + V +DE Sbjct: 2418 SVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDRPV----LVLRDVIAQDE 2471 Query: 2447 GVYMCRASNLLG 2458 Y C+ASN G Sbjct: 2472 SPYYCQASNDAG 2483 Score = 34.3 bits (75), Expect = 2.5 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384 G LECR V + + R WF N + I + + D L L V +D Y Sbjct: 2422 GGTATLECRASGVPEPSYR--WFKNNEVIPSVG----GIQSDRPVLVLRDVIAQDESPYY 2475 Query: 1385 CQATNQLGEAVTSCA-LRVIAKKDLI 1409 CQA+N G A ++ A L+V + L+ Sbjct: 2476 CQASNDAGTAKSNIATLKVYGGESLV 2501 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 13/91 (14%) Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-TIG--HRFRPI 1496 V +KP P+ +V G EC+ V + + + WFKN + + ++G RP+ Sbjct: 2404 VNVKPEITHHPED-SSVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDRPV 2460 Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527 L + D+IA+D Y C+A N GT Sbjct: 2461 -------LVLRDVIAQDESPYYCQASNDAGT 2484 Score = 33.1 bits (72), Expect = 5.7 Identities = 26/100 (26%), Positives = 38/100 (38%), Gaps = 6/100 (6%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P+ +D V G +CR +G P P WF N+ I + +S L+ Sbjct: 2408 PEITHHPEDSSVELGGTATLECRASGVPEPSYRWFKNNEVI-----PSVGGIQSDRPVLV 2462 Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQ-CRLNVIEKEQVVA 490 + +V D C A N +G L V E +VA Sbjct: 2463 LRDVIAQDESPYYCQASNDAGTAKSNIATLKVYGGESLVA 2502 >SB_56900| Best HMM Match : I-set (HMM E-Value=8e-10) Length = 968 Score = 50.8 bits (116), Expect = 3e-05 Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 11/120 (9%) Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513 +VT S++G TC A N+ G ++ V K ++V+ F + + L + Sbjct: 54 SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKI-----LSLQCK 108 Query: 514 AVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQNVAGS 571 A G P+P+ITW K G PI + G S L + + A D Y+C A N+ GS Sbjct: 109 ARGVPSPQITWYKPGGQPITAG----VSPISGGSQLQVTTTREAGDFGQYKCQASNLLGS 164 Score = 41.1 bits (92), Expect = 0.021 Identities = 18/37 (48%), Positives = 25/37 (67%) Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794 D + +AG YTC ATN+ GS TTT ++T + K +IV Sbjct: 53 DSVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIV 89 Score = 36.7 bits (81), Expect = 0.46 Identities = 16/39 (41%), Positives = 25/39 (64%) Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011 SVT +AG YTC A N +G TT+ +T+ K +I++ + Sbjct: 54 SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSST 92 Score = 35.9 bits (79), Expect = 0.80 Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 14/118 (11%) Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175 +++GTY+C ATN+ G +V++ + KP + N + + +C Sbjct: 58 SEAGTYTCTATNEMGSDTTTVQV-----TVNYKPEIVSSTTN-TSFWNKKILSLQCKARG 111 Query: 3176 VDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231 V P +I WY GQP+ + + +S G L + T+ D G+Y C+A N G Sbjct: 112 VPSP--QITWYKPGGQPI--TAGVSPIS--GGSQLQVTTTREAGDFGQYKCQASNLLG 163 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL-KKIQELEKYER--PKP-IE 2101 + GTY C ATN +G TT V V+ K + T + KKI L+ R P P I Sbjct: 59 EAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKILSLQCKARGVPSPQIT 118 Query: 2102 EEQPGQRPV 2110 +PG +P+ Sbjct: 119 WYKPGGQPI 127 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 1476 LKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE-DSGIYTCRAVNLVGTDEVSCRL 1534 LK+ +G P R + ++ D + ++G YTC A N +G+D + ++ Sbjct: 21 LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEMGSDTTTVQV 80 Query: 1535 TCRSTTDIVRSTQN 1548 T +IV ST N Sbjct: 81 TVNYKPEIVSSTTN 94 Score = 33.9 bits (74), Expect = 3.2 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY-EEDSGIYTCKATNSKGSATTS 2860 LK+ + P P+ T + + S S+ + + ++G YTC ATN GS TT+ Sbjct: 21 LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEMGSDTTT 77 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/85 (28%), Positives = 32/85 (37%), Gaps = 2/85 (2%) Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679 N PEI+ + + + CK G P P + WYK + +S + Sbjct: 83 NYKPEIVSSTTNTSFWNKKILSLQCKARGVPSPQITWYKPGGQPITAGVSPISGGSQLQV 142 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRV 4704 EA D G YKC A N G V Sbjct: 143 TTTREA--GDFGQYKCQASNLLGSV 165 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 9/120 (7%) Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVS-----PPKIAQKPRNSKLQEGADAQFQVQ 288 V + +S+T+ G + E+ V P+I N+ Q + Sbjct: 49 VYYSDSVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKILSLQCK 108 Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS-DSGHYTLLAENPNGCI 347 G P P++TW+K G + I + I + L+V T+++ D G Y A N G + Sbjct: 109 ARGVPSPQITWYKPGGQPITAGVSPI---SGGSQLQVTTTREAGDFGQYKCQASNLLGSV 165 Score = 33.1 bits (72), Expect = 5.7 Identities = 14/43 (32%), Positives = 25/43 (58%) Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416 SV ++G YTC ATN++G T+ + V K +++ + + S Sbjct: 54 SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTS 96 >SB_54071| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 266 Score = 50.8 bits (116), Expect = 3e-05 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 7/78 (8%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 P I P D+ + G ++ +C G P+PT+ W KG ++I + F + + Sbjct: 180 PTTAISPDADRTLNIGDNLQLNCSATGCPIPTLTWLKGSQIIARGRGFAL-------PIN 232 Query: 4682 ISEAFPEDEGDYKCVAYN 4699 IS A DEG+Y+C+A N Sbjct: 233 ISNAQLSDEGEYRCIADN 250 Score = 42.3 bits (95), Expect = 0.009 Identities = 49/213 (23%), Positives = 83/213 (38%), Gaps = 16/213 (7%) Query: 357 SPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT 416 +P V R+ + E +I ++ K + D +GK C Sbjct: 52 TPVREGVYTCRADNGDECASHERSVQIAVNFKPRNTTLLTNASDVTALQGKSLALSCESR 111 Query: 417 GRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK-SGET 474 +P + T++ +D + + E +L+I +V + C+++N SG + Sbjct: 112 AKPSSCDFTFYQDDVAL---VTLPGICEEGSVTSLVINSVRGCGNTTFACLSKNMISGGS 168 Query: 475 AFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534 L + + +R TLN+ G+ + LN A G P P +TW K G II Sbjct: 169 WSNITLEIQDPPTTAISPDADR--TLNI--GDNLQLNCSATGCPIPTLTWLK-GSQIIAR 223 Query: 535 PELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 G A ++I A+ SD Y+C A N Sbjct: 224 GR------GFALPINISNAQLSDEGEYRCIADN 250 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 8/79 (10%) Query: 265 PPKIAQKPRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323 PP A P + L G + Q +G P P +TW K Q + + + Sbjct: 179 PPTTAISPDADRTLNIGDNLQLNCSATGCPIPTLTWLKGSQIIARGRGFAL-------PI 231 Query: 324 RVRNTQKSDSGHYTLLAEN 342 + N Q SD G Y +A+N Sbjct: 232 NISNAQLSDEGEYRCIADN 250 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/65 (30%), Positives = 26/65 (40%), Gaps = 10/65 (15%) Query: 1725 NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYT 1784 N+ + F G P + + W R+G P+ LNM V P G YT Sbjct: 11 NETSDFSLHCDVTGSPPVSITWSRHGEPLLVQGAW----------LNMTSVTPVREGVYT 60 Query: 1785 CRAIN 1789 CRA N Sbjct: 61 CRADN 65 >SB_33923| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 221 Score = 50.4 bits (115), Expect = 3e-05 Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 3/105 (2%) Query: 4513 PPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYT 4570 PP ++T A N+ G TG P Y WL NGK + R I DG + Sbjct: 2 PPEVSVTPAITTNIAIGSTYYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSS 61 Query: 4571 LLILEAYPQDSGKYECVAINSAGEAR-CDAECVVSLPATKDKPKP 4614 L ++ A +DSG Y CVA N G + C + + A + KP Sbjct: 62 LEVINATREDSGSYACVAENIKGTGNPSEPSCQLQVRAPGEACKP 106 Score = 47.6 bits (108), Expect = 2e-04 Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 7/112 (6%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVND-SSMRVEWFHNGKPLLTGSRVKTINDF-GF 3614 PPE + TP+ S ++ C + + W HNGKPL R+ TI F G Sbjct: 2 PPEVSVTPAITTNIAIGSTYY-CTCVATGIYPTQSYAWLHNGKPLNASGRI-TIETFDGK 59 Query: 3615 VILEIGGVYQRDAGLYTCKATNRHG---EATVSCKLQVKGRQGIILEPQLPS 3663 LE+ + D+G Y C A N G + SC+LQV+ PQ S Sbjct: 60 SSLEVINATREDSGSYACVAENIKGTGNPSEPSCQLQVRAPGEACKPPQFNS 111 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/83 (31%), Positives = 39/83 (46%) Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695 PP+ V T + G ++ T + PT WL NG+ + AS R T G S Sbjct: 2 PPEVSVTPAITTNIAIGSTYYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSS 61 Query: 696 LDMLSLNIQDSGEYTCRAVSATG 718 L++++ +DSG Y C A + G Sbjct: 62 LEVINATREDSGSYACVAENIKG 84 Score = 44.0 bits (99), Expect = 0.003 Identities = 31/108 (28%), Positives = 46/108 (42%), Gaps = 6/108 (5%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYV 1502 P P N+ G + C + + W NG+P+ R I F G Sbjct: 3 PEVSVTPAITTNIAIGSTYYCTCVATGIYPTQ-SYAWLHNGKPLNASGRIT-IETFDGKS 60 Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGT---DEVSCRLTCRSTTDIVRSTQ 1547 +L++I+ EDSG Y C A N+ GT E SC+L R+ + + Q Sbjct: 61 SLEVINATREDSGSYACVAENIKGTGNPSEPSCQLQVRAPGEACKPPQ 108 Score = 43.2 bits (97), Expect = 0.005 Identities = 20/52 (38%), Positives = 27/52 (51%) Query: 1608 TLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659 T W HN KPL + R T G +L++++ EDSG+Y C A N G Sbjct: 33 TQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 42.7 bits (96), Expect = 0.007 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 499 TLNVREGEPVVLNARAVGT-PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557 T N+ G A G PT W +G P+ + + I T G S+L++ A D Sbjct: 12 TTNIAIGSTYYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATRED 71 Query: 558 AAWYQCTAQNVAGS 571 + Y C A+N+ G+ Sbjct: 72 SGSYACVAENIKGT 85 Score = 42.3 bits (95), Expect = 0.009 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI-TFDFGY 2299 PP TT++ G T + C ++ P + HNGK L ++ R I TFD G Sbjct: 2 PPEVSVTPAITTNIAIGSTYYCTCVATGIY-PTQSYAWLHNGKPLNASGRITIETFD-GK 59 Query: 2300 VSLDIQHCVPEDAGEYSVKAINALG 2324 SL++ + ED+G Y+ A N G Sbjct: 60 SSLEVINATREDSGSYACVAENIKG 84 Score = 41.5 bits (93), Expect = 0.016 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 5/83 (6%) Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQ-SMVIEWFYNGKTIEASHRIRTVYAF-G 3104 PPE + +I+ G Y + + TG + W +NGK + AS RI T+ F G Sbjct: 2 PPEVSVTPAITTNIAIGST--YYCTCVATGIYPTQSYAWLHNGKPLNASGRI-TIETFDG 58 Query: 3105 MVVLEILGTKTTDSGTYSCRATN 3127 LE++ DSG+Y+C A N Sbjct: 59 KSSLEVINATREDSGSYACVAEN 81 Score = 40.7 bits (91), Expect = 0.028 Identities = 21/58 (36%), Positives = 26/58 (44%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860 PT W N KPL + R SL++ + EDSG Y C A N KG+ S Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPS 89 Score = 40.7 bits (91), Expect = 0.028 Identities = 21/53 (39%), Positives = 28/53 (52%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852 PT W +G+P+ AS RIT G SL +++ ED+GSY A N G Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 39.5 bits (88), Expect = 0.065 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 1/64 (1%) Query: 3169 FECTVVPVDD-PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 + CT V P W HNG+P+ S RI + G L++ DSG Y C A Sbjct: 21 YYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAE 80 Query: 3228 NKYG 3231 N G Sbjct: 81 NIKG 84 Score = 39.5 bits (88), Expect = 0.065 Identities = 19/58 (32%), Positives = 28/58 (48%) Query: 1207 PTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264 PT W HNG+ + R G +L++I+AT D+G Y A N G+ + S Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPS 89 Score = 39.5 bits (88), Expect = 0.065 Identities = 21/53 (39%), Positives = 26/53 (49%) Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792 P WL NG P+ AS R+T G +L + EDSG+Y C A N G Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 39.1 bits (87), Expect = 0.086 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKT-TYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059 PT W NG+P+ R T+D G +L+++ A ED+G+Y C A N G Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFD-GKSSLEVINATREDSGSYACVAENIKG 84 Score = 39.1 bits (87), Expect = 0.086 Identities = 20/52 (38%), Positives = 27/52 (51%) Query: 945 WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 WL +G+P+ AS RIT G +L + + T D+G Y C A N G S Sbjct: 38 WLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPS 89 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 3/86 (3%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GF 3752 PP +V ++ G + C + PT W HNG+P R+ T+ F G Sbjct: 2 PPEVSVTPAITTNIAIGSTYYCTCVATGIY-PTQSYAWLHNGKPLNASGRI-TIETFDGK 59 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778 +L++ D+G Y C A N G+ Sbjct: 60 SSLEVINATREDSGSYACVAENIKGT 85 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 3/73 (4%) Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDED 2445 NI G T + C + PT W N K + S RIT +T D G S+ + + ED Sbjct: 14 NIAIGSTYYCTCVATGIY-PTQSYAWLHNGKPLNASGRITIETFD-GKSSLEVINATRED 71 Query: 2446 EGVYMCRASNLLG 2458 G Y C A N+ G Sbjct: 72 SGSYACVAENIKG 84 Score = 37.5 bits (83), Expect = 0.26 Identities = 18/53 (33%), Positives = 26/53 (49%) Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191 P + W HNG+ + A R G +L+++ EDSG+Y C A N G Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 37.5 bits (83), Expect = 0.26 Identities = 18/52 (34%), Positives = 26/52 (50%) Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAG 1125 T + W NGK + ++ RI G +L++ + EDSG Y VA N G Sbjct: 33 TQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 37.1 bits (82), Expect = 0.35 Identities = 18/53 (33%), Positives = 24/53 (45%) Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926 P W NGK L + R G ++L+++ EDSG Y C A N G Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 36.7 bits (81), Expect = 0.46 Identities = 27/83 (32%), Positives = 31/83 (37%), Gaps = 1/83 (1%) Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497 P W P+ S I TF KS L + EDS +A VAEN GT S Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPSEP 91 Query: 4498 LVVEEKRRQGRGGIVPPSFTLTA 4520 + R G PP F A Sbjct: 92 SCQLQVRAPGE-ACKPPQFNSIA 113 Score = 36.7 bits (81), Expect = 0.46 Identities = 19/53 (35%), Positives = 25/53 (47%) Query: 293 PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345 P W NG+ L S + I T ++L V N + DSG Y +AEN G Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 36.7 bits (81), Expect = 0.46 Identities = 17/53 (32%), Positives = 25/53 (47%) Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993 P W NGK L R + + G +L++++ DSG Y C A N +G Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 5/84 (5%) Query: 2672 PNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA-VST 2729 P W NG L R+ TFD G +L + + +DSG Y C A N+ G S Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFD-GKSSLEVINATREDSGSYACVAENIKGTGNPSE 90 Query: 2730 ASIKIEDRHWLLGESLHPDSLDRI 2753 S +++ R GE+ P + I Sbjct: 91 PSCQLQVR--APGEACKPPQFNSI 112 Score = 35.5 bits (78), Expect = 1.1 Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 5/106 (4%) Query: 4622 PPEI-IEPLKDKIVAEGQAIEFSCKIVG-KPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679 PPE+ + P +A G +C G P + W K + S + + + Sbjct: 2 PPEVSVTPAITTNIAIGSTYYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSS 61 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGR---VTVAAKLKVTQPDQADNLP 4722 L + A ED G Y CVA N G + +L+V P +A P Sbjct: 62 LEVINATREDSGSYACVAENIKGTGNPSEPSCQLQVRAPGEACKPP 107 Score = 35.5 bits (78), Expect = 1.1 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 3/108 (2%) Query: 1341 TMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG---EAVTS 1397 T W NGKP+ R +L++++ EDSG Y C A N G + S Sbjct: 33 TQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPSEPS 92 Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPR 1445 C L+V A + Q S D +TD + S K R Sbjct: 93 CQLQVRAPGEACKPPQFNSIAISESECHDCFCMGRTDQCNSSTLYKDR 140 Score = 33.9 bits (74), Expect = 3.2 Identities = 19/53 (35%), Positives = 22/53 (41%) Query: 4003 PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055 P W NGKPL R T G ++ EDSG Y C A N+ G Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 33.5 bits (73), Expect = 4.3 Identities = 20/53 (37%), Positives = 21/53 (39%) Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYG 3502 P W NGK L A R G LE+ EDSG Y C A N G Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 2/54 (3%) Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDF-GIVILDILYCYEENSGEYECVATNKLG 3364 P W +NGK L R T F G L+++ E+SG Y CVA N G Sbjct: 32 PTQSYAWLHNGKPLNASGRI-TIETFDGKSSLEVINATREDSGSYACVAENIKG 84 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/50 (36%), Positives = 22/50 (44%) Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908 P W NGK L + R G SL+++ EDSG Y C A N Sbjct: 32 PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAEN 81 >SB_2143| Best HMM Match : ig (HMM E-Value=1.9e-09) Length = 306 Score = 50.4 bits (115), Expect = 3e-05 Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 13/125 (10%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L+I NV D+G + GET F+ ++ V+ P V + + V + Sbjct: 83 LIIKNVQPKDAGEYAMTLVDDGGETTFEASKFTLD---VLVPPSVTH-ANITVNKTNTAE 138 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 L A G PTP +TW + G + + G TL K SD Y CTA N Sbjct: 139 LTCSATGNPTPNVTWTRSG---------KENVLGTGETLTFSDVKISDGGCYVCTATNNI 189 Query: 570 GSTAT 574 GS A+ Sbjct: 190 GSGAS 194 Score = 37.5 bits (83), Expect = 0.26 Identities = 52/199 (26%), Positives = 76/199 (38%), Gaps = 33/199 (16%) Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 LII+ V +D+ +A + GG A+ + +VPPS +T N+ V Sbjct: 83 LIIKNVQPKDAGEYAMTLVDDGGETTFEASKFTLDV-------LVPPS--VTHANITVNK 133 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLILEAYPQDSGKYEC 4586 L TG +V W ++GK+ +L GT TL + D G Y C Sbjct: 134 TNTAELTCSATGNPTPNVTWTRSGKE-------NVL---GTGETLTFSDVKISDGGCYVC 183 Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646 A N+ G C+ + KP T A + G AI +C Sbjct: 184 TATNNIGSGASGTVCL----TVQYKP-VHTNIAGVESYNVRQC-------GAAISLTCSA 231 Query: 4647 VGKP-LPTVQWYKGDKLIK 4664 VG+P L T Y + LI+ Sbjct: 232 VGEPQLITYHLYMDNLLIR 250 Score = 34.7 bits (76), Expect = 1.9 Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 13/117 (11%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V + C TG P P VTW + ++ +L L ++V +SD G Sbjct: 131 VNKTNTAELTCSATGNPTPNVTWTRSGKE-------NVL---GTGETLTFSDVKISDGGC 180 Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTP 518 C A N G A ++ + V + + NVR+ G + L AVG P Sbjct: 181 YVCTATNNIGSGASGTVCLTVQYKPVHTN--IAGVESYNVRQCGAAISLTCSAVGEP 235 Score = 33.9 bits (74), Expect = 3.2 Identities = 15/42 (35%), Positives = 21/42 (50%) Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161 +TV + A C TG+P P V W +G V G+ LT+ Sbjct: 129 ITVNKTNTAELTCSATGNPTPNVTWTRSGKENVLGTGETLTF 170 Score = 32.3 bits (70), Expect = 9.9 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 4/93 (4%) Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725 S+Y + T + TL I P+D G+Y + G T A K T P++T Sbjct: 69 SRYSLSTATFNPITLIIKNVQPKDAGEYAMTLVDDGGETTFEAS-KFTLDVLVP--PSVT 125 Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758 +I V + A+ T P + W R G Sbjct: 126 H-ANITVNKTNTAELTCSATGNPTPNVTWTRSG 157 >SB_30548| Best HMM Match : I-set (HMM E-Value=2.1e-11) Length = 203 Score = 50.4 bits (115), Expect = 3e-05 Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 5/72 (6%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C G P P+VTW +N+ +R + +V E L I N+ D G + CVARN +G Sbjct: 21 CPTRGLPAPDVTWEMNNTNVRP--GGRFVVQEG---TLTIRNLVKQDQGNIRCVARNAAG 75 Query: 473 ETAFQCRLNVIE 484 + +LNVIE Sbjct: 76 QDTATSKLNVIE 87 Score = 47.6 bits (108), Expect = 2e-04 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V G + C G P P V W + ++P F E TL I +D+G+ Sbjct: 11 VLSGITLTIICPTRGLPAPDVTWEMNNTNVRPGGRF----VVQEGTLTIRNLVKQDQGNI 66 Query: 4694 KCVAYNSAGRVTVAAKLKVTQ 4714 +CVA N+AG+ T +KL V + Sbjct: 67 RCVARNAAGQDTATSKLNVIE 87 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%) Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584 V SG + + G DV W N V+P + + ++GT T+ L QD G Sbjct: 11 VLSGITLTIICPTRGLPAPDVTWEMNNTNVRPG--GRFVVQEGTLTIRNL--VKQDQGNI 66 Query: 4585 ECVAINSAGE 4594 CVA N+AG+ Sbjct: 67 RCVARNAAGQ 76 >SB_45888| Best HMM Match : Pkinase_Tyr (HMM E-Value=1.4e-25) Length = 561 Score = 50.0 bits (114), Expect = 5e-05 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 5/86 (5%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V EG+ + +C+ P PTV WYK DK S + + +L IS A +D+G+Y Sbjct: 198 VTEGEPVNITCQSNDLPRPTVTWYKDDKPANQSVLWYRGSS----SLVISAASIKDQGEY 253 Query: 4694 KCVAYNSAGRV-TVAAKLKVTQPDQA 4718 C A N+ G + L+VT P A Sbjct: 254 FCTAENTYGHAQSNKTNLEVTDPPSA 279 Score = 48.8 bits (111), Expect = 1e-04 Identities = 36/107 (33%), Positives = 48/107 (44%), Gaps = 6/107 (5%) Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523 TC G T+ Q + VI+ A LNV EGEPV + ++ P P +T Sbjct: 162 TCRTSTDFGCTSGQVYIRVIDPSP--ASLIATPPLYLNVTEGEPVNITCQSNDLPRPTVT 219 Query: 524 WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 W KD P N + + G+S+L I A D Y CTA+N G Sbjct: 220 WYKDDKP--ANQSVLWYR--GSSSLVISAASIKDQGEYFCTAENTYG 262 Score = 41.5 bits (93), Expect = 0.016 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 14/122 (11%) Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874 R+ D P +++TPP ++ V E E V C + + P+ + WY++ K P+ Sbjct: 179 RVID-PSPASLIATPPLYLN------VTEGEPVNITC--QSNDLPRPTVTWYKDDK--PA 227 Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE-DFTKATISCKKLPDIILQNQV 3933 ++ G SL I +D GEY C A N +G K + P + ++Q Sbjct: 228 NQS--VLWYRGSSSLVISAASIKDQGEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQA 285 Query: 3934 PR 3935 R Sbjct: 286 VR 287 Score = 39.9 bits (89), Expect = 0.049 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461 +VTEG+ C+ P P VTW+ +D+ N +L G+ +L+I+ ++ D G Sbjct: 197 NVTEGEPVNITCQSNDLPRPTVTWYKDDKPA----NQSVLWYR-GSSSLVISAASIKDQG 251 Query: 462 VVTCVARNKSG 472 C A N G Sbjct: 252 EYFCTAENTYG 262 Score = 38.7 bits (86), Expect = 0.11 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 6/57 (10%) Query: 99 PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155 P P V+W + P N+ + Y G SL+I D+GEY CTA N YG A Sbjct: 214 PRPTVTWYKDDKP---ANQSVLWYR---GSSSLVISAASIKDQGEYFCTAENTYGHA 264 Score = 38.3 bits (85), Expect = 0.15 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 12/103 (11%) Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL-QSGHRYRTSNDFGFAALDILTVYGEDS 1914 ++EG+ + C+ P P V WY + K QS YR S+ +A I +D Sbjct: 198 VTEGEPVNITCQSNDLPRPT--VTWYKDDKPANQSVLWYRGSSSLVISAASI-----KDQ 250 Query: 1915 GEYTCKAINNLGQAVSS-IRLNVQSKESIIRDSQ---HESALE 1953 GEY C A N G A S+ L V S + SQ ES LE Sbjct: 251 GEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESGLE 293 Score = 37.9 bits (84), Expect = 0.20 Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 6/73 (8%) Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048 VTEG PV++ + PT V WY + +P Q + G +L I A +D G Sbjct: 198 VTEGEPVNITCQSNDLPRPT--VTWYKDDKPANQS----VLWYRGSSSLVISAASIKDQG 251 Query: 2049 TYMCKATNAVGEA 2061 Y C A N G A Sbjct: 252 EYFCTAENTYGHA 264 Score = 37.5 bits (83), Expect = 0.26 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 7/115 (6%) Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG 3751 P+P ++V EG PV+ C+ + PT + W+ + +P + L G Sbjct: 183 PSPASLIATPPLYLNVTEGEPVNITCQSNDLPRPT--VTWYKDDKP----ANQSVLWYRG 236 Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSA-TTTAKITCSAKRDIVLESQLPQGMSG 3805 +L I +D GEY C A N +G A + + + V +SQ + SG Sbjct: 237 SSSLVISAASIKDQGEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESG 291 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 7/103 (6%) Query: 3984 SLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043 ++ E E CQ + P V W+ + KP N+ Y G ++ +D Sbjct: 197 NVTEGEPVNITCQSNDL--PRPTVTWYKDDKPA---NQSVLWYR-GSSSLVISAASIKDQ 250 Query: 4044 GEYLCRATNLYG-MDETKAVIKTTGKPGIVYDSQLPKHMKSIE 4085 GEY C A N YG K ++ T P V+ SQ + +E Sbjct: 251 GEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESGLE 293 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 4/88 (4%) Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317 R + P IA P + EG Q + PRP VTW+K+ + S ++ Sbjct: 179 RVIDPSPASLIATPPLYLNVTEGEPVNITCQSNDLPRPTVTWYKDDKPANQS----VLWY 234 Query: 318 HNHTTLRVRNTQKSDSGHYTLLAENPNG 345 ++L + D G Y AEN G Sbjct: 235 RGSSSLVISAASIKDQGEYFCTAENTYG 262 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA-TTSANLTI 1001 V W KD +P S + G +L I + ++ D G Y C A N G A + NL + Sbjct: 218 VTWYKDDKPANQS----VLWYRGSSSLVISAASIKDQGEYFCTAENTYGHAQSNKTNLEV 273 Query: 1002 VTKKDIIAESQ 1012 + +SQ Sbjct: 274 TDPPSAVFKSQ 284 Score = 34.7 bits (76), Expect = 1.9 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 7/101 (6%) Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDS 3490 N+ EGE + + D P V WY + K + G L IS +D Sbjct: 197 NVTEGEPVNITCQ--SNDLPRPTVTWYKDDKPANQSVLWYR----GSSSLVISAASIKDQ 250 Query: 3491 GEYLCRAYNNYGEAVTT-ASMKVQGKRNIILESQLPKGMEG 3530 GEY C A N YG A + +++V + + +SQ + G Sbjct: 251 GEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESG 291 Score = 34.3 bits (75), Expect = 2.5 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 6/72 (8%) Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446 N+ EG+ + C+ + PT V W++++K S + G S+ IS +D+ Sbjct: 197 NVTEGEPVNITCQSNDLPRPT--VTWYKDDKPANQSVLWYR----GSSSLVISAASIKDQ 250 Query: 2447 GVYMCRASNLLG 2458 G Y C A N G Sbjct: 251 GEYFCTAENTYG 262 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 +NVT G+ V + + V W K+ K +L G+ +L+I A +D G Sbjct: 196 LNVTEGEPVNITCQSNDLPRPTVTWYKDDKPAN----QSVLWYRGSSSLVISAASIKDQG 251 Query: 4583 KYECVAINSAGEAR 4596 +Y C A N+ G A+ Sbjct: 252 EYFCTAENTYGHAQ 265 Score = 33.5 bits (73), Expect = 4.3 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 7/100 (7%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG+ ++ C PT + W+ ++KP + SL I+ +D G Y Sbjct: 200 EGEPVNITCQSNDLPRPT--VTWYKDDKPANQSVLWYRGSS----SLVISAASIKDQGEY 253 Query: 2847 TCKATNSKGSA-TTSGSLRCTGDKNIYFDTQHPQGKAGLE 2885 C A N+ G A + +L T + F +Q + ++GLE Sbjct: 254 FCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESGLE 293 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 5/99 (5%) Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464 + PS + V E E + + P P + WY+++ P S + + Sbjct: 181 IDPSPASLIATPPLYLNVTEGEPVNITCQSNDLPRPTVTWYKDDKPANQS----VLWYRG 236 Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCS-ANLVVEE 4502 S L+I ++D + AEN G A+ + NL V + Sbjct: 237 SSSLVISAASIKDQGEYFCTAENTYGHAQSNKTNLEVTD 275 >SB_6364| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 357 Score = 50.0 bits (114), Expect = 5e-05 Identities = 53/203 (26%), Positives = 76/203 (37%), Gaps = 34/203 (16%) Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT------------- 4679 I EG + E +C P + WY+ D ++ SK +Q+S++ E Sbjct: 9 ISREGVSPEMTCNTTANPSADITWYRDDVMLT-SKRYQISQSVTESQIPRRIQMLCPSKV 67 Query: 4680 --------LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731 L I EA D G Y C A N G L+V P + L P ++ Sbjct: 68 PHPITQSILVIMEARGSDTGTYTCRARNMMGARDRHVVLRVQVP-----VAILIPHKNQT 122 Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLR-EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790 V EG + P I W R +G+ +P H N VL + N + GT Sbjct: 123 VLEGNNVTLSCNASGIPAPVITWYRKDGSYMPVN------HRVVNGVLTVFNITKAHEGT 176 Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813 + C+A G T A L +K Sbjct: 177 YVCKAKNVLGAKTTEATLNCNNK 199 Score = 50.0 bits (114), Expect = 5e-05 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 21/140 (15%) Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630 L+I+EA D+G Y C A N G AR D V+ + P I+ P K Sbjct: 76 LVIMEARGSDTGTYTCRARNMMG-AR-DRHVVLRV--------------QVPVAILIPHK 119 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 ++ V EG + SC G P P + WY+ K Y ++ L + E Sbjct: 120 NQTVLEGNNVTLSCNASGIPAPVITWYR-----KDGSYMPVNHRVVNGVLTVFNITKAHE 174 Query: 4691 GDYKCVAYNSAGRVTVAAKL 4710 G Y C A N G T A L Sbjct: 175 GTYVCKAKNVLGAKTTEATL 194 Score = 49.6 bits (113), Expect = 6e-05 Identities = 54/194 (27%), Positives = 73/194 (37%), Gaps = 31/194 (15%) Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESG----------------- 446 EG C T P ++TW+ +D + Y V ES Sbjct: 12 EGVSPEMTCNTTANPSADITWYRDDVMLTSKRYQISQSVTESQIPRRIQMLCPSKVPHPI 71 Query: 447 -NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505 L+I SD+G TC ARN G L V ++ P V EG Sbjct: 72 TQSILVIMEARGSDTGTYTCRARNMMGARDRHVVLRVQVPVAILIPH-----KNQTVLEG 126 Query: 506 EPVVLNARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 V L+ A G P P ITW +KDG + N + +G + +I +A Y C Sbjct: 127 NNVTLSCNASGIPAPVITWYRKDGSYMPVNHRV---VNGVLTVFNITKAHEGT---YVCK 180 Query: 565 AQNVAGSTATRARL 578 A+NV G+ T A L Sbjct: 181 AKNVLGAKTTEATL 194 Score = 49.6 bits (113), Expect = 6e-05 Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 15/140 (10%) Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166 +L I+ + +D+GTY+CRA N G + V L Q P + + +G + Sbjct: 75 ILVIMEARGSDTGTYTCRARNMMGARDRHVVLRV------QVPVAILIPHKNQTVLEGNN 128 Query: 3167 AHFECTVVPVDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 C + P I WY +G M + R+ V+ T+ H+ G YVC+ Sbjct: 129 VTLSCNASGIPAP--VITWYRKDGSYMPVNHRV-----VNGVLTVFNITKAHE-GTYVCK 180 Query: 3226 AYNKYGEDFTRATINCYGKG 3245 A N G T AT+NC KG Sbjct: 181 AKNVLGAKTTEATLNCNNKG 200 Score = 49.2 bits (112), Expect = 8e-05 Identities = 47/214 (21%), Positives = 85/214 (39%), Gaps = 23/214 (10%) Query: 278 QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEII--TTHNHTTLRVRNTQKSDSGH 335 +EG + + NP +TW+++ ++ S +++I T + R++ S H Sbjct: 11 REGVSPEMTCNTTANPSADITWYRDDV-MLTSKRYQISQSVTESQIPRRIQMLCPSKVPH 69 Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395 P + A S T +Y R++ + + R R+++ L P Sbjct: 70 -------PITQSILVIMEARGSDTGTYTC--RARNMMGARDRHVVLRVQVPVAILIPH-- 118 Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455 +++ V EG C +G P P +TW+ D NH+++ N L + N+ Sbjct: 119 ---KNQTVLEGNNVTLSCNASGIPAPVITWYRKDGSYM-PVNHRVV-----NGVLTVFNI 169 Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489 T + G C A+N G + LN K V Sbjct: 170 TKAHEGTYVCKAKNVLGAKTTEATLNCNNKGPTV 203 Score = 41.5 bits (93), Expect = 0.016 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTVYDM 3884 V P + K+ TV E V C P I WYR +G +P HR V + Sbjct: 108 VQVPVAILIPHKNQTVLEGNNVTLSCNASGIPAPV--ITWYRKDGSYMPVNHR--VVNGV 163 Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISC 3921 L + + G Y+C+A N G T+AT++C Sbjct: 164 ----LTVFNITKAHEGTYVCKAKNVLGAKTTEATLNC 196 Score = 38.7 bits (86), Expect = 0.11 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 8/91 (8%) Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834 + I H N V EG+N+ CN S P I W+ + G+ H L Sbjct: 114 ILIPHKNQTVL-EGNNVTLSCNA--SGIPAPVITWYRKD-----GSYMPVNHRVVNGVLT 165 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRC 2865 + + + G Y CKA N G+ TT +L C Sbjct: 166 VFNITKAHEGTYVCKAKNVLGAKTTEATLNC 196 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 7/75 (9%) Query: 79 KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138 KN +G N G P PV++W RK M N + + L + I Sbjct: 119 KNQTVLEGNNVTLSCNASGIPAPVITWYRKDGSY-------MPVNHRVVNGVLTVFNITK 171 Query: 139 GDEGEYTCTARNQYG 153 EG Y C A+N G Sbjct: 172 AHEGTYVCKAKNVLG 186 Score = 34.3 bits (75), Expect = 2.5 Identities = 17/50 (34%), Positives = 28/50 (56%) Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953 L I+ G D+G YTC+A N +G + L VQ +I+ ++++ LE Sbjct: 76 LVIMEARGSDTGTYTCRARNMMGARDRHVVLRVQVPVAILIPHKNQTVLE 125 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 12/105 (11%) Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF-KNGQPVTIGHRFRPIHDFGYV 1502 P + P + V+EG +V C + + W+ K+G + + HR ++ Sbjct: 111 PVAILIPHKNQTVLEGNNVTLSCNASGIPAP--VITWYRKDGSYMPVNHRV--VNG---- 162 Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS---TTDIVR 1544 L + ++ G Y C+A N++G L C + T IVR Sbjct: 163 VLTVFNITKAHEGTYVCKAKNVLGAKTTEATLNCNNKGPTVTIVR 207 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 5/89 (5%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 P I +N + EG + SG P P +TW++ + N H ++ + L Sbjct: 111 PVAILIPHKNQTVLEGNNVTLSCNASGIPAPVITWYRKDGSYMPVN-HRVV----NGVLT 165 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYL 353 V N K+ G Y A+N G T L Sbjct: 166 VFNITKAHEGTYVCKAKNVLGAKTTEATL 194 Score = 33.9 bits (74), Expect = 3.2 Identities = 28/113 (24%), Positives = 47/113 (41%), Gaps = 12/113 (10%) Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL-KNGQSIEASSRFTSIFR 690 RV P ++P K+ T +EG + G P I W K+G + + R + Sbjct: 107 RVQVPVAILIPHKNQTVLEGNNVTLSCNAS--GIPAPVITWYRKDGSYMPVNHRVVN--- 161 Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT---PRATIERTSQH 740 G +++ ++ G Y C+A + G T+A L+ P TI R + Sbjct: 162 -GVLTV--FNITKAHEGTYVCKAKNVLGAKTTEATLNCNNKGPTVTIVRVGTY 211 Score = 32.7 bits (71), Expect = 7.5 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 9/91 (9%) Query: 1983 PIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYC-NGRPVQQGHRFKTTYDFGYVALDILY 2041 P KN V EG+ V L + + P + WY +G + HR L + Sbjct: 117 PHKNQTVLEGNNVTLSCNASGIPAPV--ITWYRKDGSYMPVNHRVVNG------VLTVFN 168 Query: 2042 AYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072 GTY+CKA N +G T +++ + K Sbjct: 169 ITKAHEGTYVCKAKNVLGAKTTEATLNCNNK 199 Score = 32.7 bits (71), Expect = 7.5 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 7/71 (9%) Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447 + EG C G P + W+R +D S + H +T+ ++ EG Sbjct: 123 VLEGNNVTLSCNAS--GIPAPVITWYR-----KDGSYMPVNHRVVNGVLTVFNITKAHEG 175 Query: 2448 VYMCRASNLLG 2458 Y+C+A N+LG Sbjct: 176 TYVCKAKNVLG 186 Score = 32.3 bits (70), Expect = 9.9 Identities = 17/50 (34%), Positives = 27/50 (54%) Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286 L I+ A +DTG YT RA N +G+ ++RV I+ +N+ +E Sbjct: 76 LVIMEARGSDTGTYTCRARNMMGARDRHVVLRVQVPVAILIPHKNQTVLE 125 >SB_39808| Best HMM Match : EGF_CA (HMM E-Value=6.3e-35) Length = 850 Score = 49.6 bits (113), Expect = 6e-05 Identities = 31/98 (31%), Positives = 42/98 (42%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 P II+ KD + +G F+CK G P P + W G P L Sbjct: 153 PTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLLPSGALV 212 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719 + DEG Y+CVA N AG T +A LKV ++ + Sbjct: 213 VKGVNLTDEGMYRCVASNPAGAATRSAVLKVQDLNECE 250 Score = 47.2 bits (107), Expect = 3e-04 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 8/95 (8%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSW---TRKKAPLVECNKYSMRYNEQTG 127 P Q K+ QGG A F K RG+P P ++W APL ++Y + +G Sbjct: 153 PTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLL---PSG 209 Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162 +L++K + DEG Y C A N G A S ++ Sbjct: 210 --ALVVKGVNLTDEGMYRCVASNPAGAATRSAVLK 242 Score = 46.8 bits (106), Expect = 4e-04 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 6/106 (5%) Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF--KNGQR-LINSNKHEIITTH 318 P P I Q P++ +++G A F + G+P P + W NG L ++++++ + Sbjct: 150 PYLPTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLLPS- 208 Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364 L V+ +D G Y +A NP G S L V+ E ++ Sbjct: 209 --GALVVKGVNLTDEGMYRCVASNPAGAATRSAVLKVQDLNECEIR 252 Score = 45.6 bits (103), Expect = 0.001 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 9/108 (8%) Query: 380 EERIEISEKA-LAPQFV-KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN---DRQIRD 434 E R++ E P F+ + +D + +G F+C+ G P P + W I D + Sbjct: 140 ESRLKYVENTPYLPTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPT 199 Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482 D + +L SG AL++ V L+D G+ CVA N +G L V Sbjct: 200 DDRYDLL--PSG--ALVVKGVNLTDEGMYRCVASNPAGAATRSAVLKV 243 Score = 41.9 bits (94), Expect = 0.012 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%) Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ--KDGVPIIPN 534 + RL +E + ++ + +R+G V N +A G P P I W +G +P Sbjct: 140 ESRLKYVENTPYLPTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPT 199 Query: 535 PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576 + GA L + +D Y+C A N AG+ ATR+ Sbjct: 200 DDRYDLLPSGA--LVVKGVNLTDEGMYRCVASNPAGA-ATRS 238 Score = 39.9 bits (89), Expect = 0.049 Identities = 15/46 (32%), Positives = 22/46 (47%) Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149 E+ P + P VT+ +G A F C+ GHP P + W + N Sbjct: 147 ENTPYLPTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGAN 192 Score = 39.5 bits (88), Expect = 0.065 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 8/98 (8%) Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWF--HNG-RPFATGSRVH 3745 + P P F ++ ++ + +GG F+C+ G P I W NG P T R Sbjct: 147 ENTPYLPTFIIQTPKDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYD 204 Query: 3746 TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTA 3783 L AL + + D G Y C A+N G+AT +A Sbjct: 205 LLPSG---ALVVKGVNLTDEGMYRCVASNPAGAATRSA 239 Score = 35.9 bits (79), Expect = 0.80 Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 8/97 (8%) Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWF--HNGK-PLLTGSRVKTINDFG 3613 P TP D+ + + +A F C+ + + W NG PL T R + Sbjct: 153 PTFIIQTPKDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYDLLPSGA 210 Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 V+ GV D G+Y C A+N G AT S L+V+ Sbjct: 211 LVVK---GVNLTDEGMYRCVASNPAGAATRSAVLKVQ 244 Score = 35.5 bits (78), Expect = 1.1 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%) Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV-LQSGHRYRTSNDFGFA 1902 P FI Q + +G +A + C+ +P P++ NG L + RY Sbjct: 153 PTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLLPS---G 209 Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 AL + V D G Y C A N G A S L VQ Sbjct: 210 ALVVKGVNLTDEGMYRCVASNPAGAATRSAVLKVQ 244 Score = 35.1 bits (77), Expect = 1.4 Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 6/101 (5%) Query: 630 EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL--KNGQSIEASSRFTS 687 E+ Y P I K VT +GG F + G P I W NG + + Sbjct: 147 ENTPYLPTFIIQTPKDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYD 204 Query: 688 IFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 + G +L + +N+ D G Y C A + G A AVL V Sbjct: 205 LLPSG--ALVVKGVNLTDEGMYRCVASNPAGAATRSAVLKV 243 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/93 (26%), Positives = 35/93 (37%), Gaps = 2/93 (2%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P F ++I++GG A F + G + W + A Sbjct: 153 PTFIIQTPKDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYDLLPSGA 210 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 L +K V + D G Y C A N G AT SA L + Sbjct: 211 LVVKGVNLTDEGMYRCVASNPAGAATRSAVLKV 243 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK-IRAGHRYRTTHDFGYV 2167 P F+ +++G A F C+ PH+ NG + RY V Sbjct: 153 PTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLLPSGALV 212 Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + T D G Y C A+N G A + LKV Sbjct: 213 VKGVNLT---DEGMYRCVASNPAGAATRSAVLKV 243 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 8/86 (9%) Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFN---NKPLPSGTRYKSTHDFSYVSLDITHT 2838 ++ ++G F C P I W + PLP+ RY + V + T Sbjct: 162 DVTIRQGGTAVFNCKARGH--PAPHIAWAIGANGDAPLPTDDRYDLLPSGALVVKGVNLT 219 Query: 2839 YEEDSGIYTCKATNSKGSATTSGSLR 2864 D G+Y C A+N G+AT S L+ Sbjct: 220 ---DEGMYRCVASNPAGAATRSAVLK 242 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 8/89 (8%) Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWL--RNG-VPIEASNRLTTMHDFGYVALNMKY 1774 KD+ + + A F + G P + W NG P+ +R + AL +K Sbjct: 161 KDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYDLLPSG---ALVVKG 215 Query: 1775 VNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 VN D G Y C A N G A S+ L VQ Sbjct: 216 VNLTDEGMYRCVASNPAGAATRSAVLKVQ 244 >SB_28651| Best HMM Match : ig (HMM E-Value=1.4e-09) Length = 221 Score = 49.6 bits (113), Expect = 6e-05 Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 11/120 (9%) Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513 +VT S++G TC A N+ G ++ V K ++V+ F + + L + Sbjct: 54 SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKI-----LSLQCK 108 Query: 514 AVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQNVAGS 571 A G P+P+ITW K G PI + G S L + + A D Y+C A N+ GS Sbjct: 109 ARGVPSPQITWYKPGGQPITAG----VSPISGGSQLQVTTTREAGDYGQYKCRAFNLLGS 164 Score = 41.1 bits (92), Expect = 0.021 Identities = 18/37 (48%), Positives = 25/37 (67%) Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794 D + +AG YTC ATN+ GS TTT ++T + K +IV Sbjct: 53 DSVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIV 89 Score = 39.5 bits (88), Expect = 0.065 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 14/118 (11%) Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175 +++GTY+C ATN+ G +V++ + KP + N + + +C Sbjct: 58 SEAGTYTCTATNEMGSDTTTVQV-----TVNYKPEIVSSTTN-TSFWNKKILSLQCKARG 111 Query: 3176 VDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231 V P +I WY GQP+ + + +S G L + T+ D G+Y CRA+N G Sbjct: 112 VPSP--QITWYKPGGQPI--TAGVSPIS--GGSQLQVTTTREAGDYGQYKCRAFNLLG 163 Score = 36.7 bits (81), Expect = 0.46 Identities = 16/39 (41%), Positives = 25/39 (64%) Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011 SVT +AG YTC A N +G TT+ +T+ K +I++ + Sbjct: 54 SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSST 92 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 2/85 (2%) Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679 N PEI+ + + + CK G P P + WYK + +S + Sbjct: 83 NYKPEIVSSTTNTSFWNKKILSLQCKARGVPSPQITWYKPGGQPITAGVSPISGGSQLQV 142 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRV 4704 EA D G YKC A+N G V Sbjct: 143 TTTREA--GDYGQYKCRAFNLLGSV 165 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL-KKIQELEKYER--PKP-IE 2101 + GTY C ATN +G TT V V+ K + T + KKI L+ R P P I Sbjct: 59 EAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKILSLQCKARGVPSPQIT 118 Query: 2102 EEQPGQRPV 2110 +PG +P+ Sbjct: 119 WYKPGGQPI 127 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 1476 LKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE-DSGIYTCRAVNLVGTDEVSCRL 1534 LK+ +G P R + ++ D + ++G YTC A N +G+D + ++ Sbjct: 21 LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEMGSDTTTVQV 80 Query: 1535 TCRSTTDIVRSTQN 1548 T +IV ST N Sbjct: 81 TVNYKPEIVSSTTN 94 Score = 33.9 bits (74), Expect = 3.2 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY-EEDSGIYTCKATNSKGSATTS 2860 LK+ + P P+ T + + S S+ + + ++G YTC ATN GS TT+ Sbjct: 21 LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEMGSDTTT 77 Score = 33.1 bits (72), Expect = 5.7 Identities = 14/43 (32%), Positives = 25/43 (58%) Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416 SV ++G YTC ATN++G T+ + V K +++ + + S Sbjct: 54 SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTS 96 Score = 33.1 bits (72), Expect = 5.7 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 7/98 (7%) Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK-NGQPVTIGH 1491 T + +V KP V+ + + + + +CK V ++ W+K GQP+T G Sbjct: 75 TTTVQVTVNYKPEIVSSTTNT-SFWNKKILSLQCKARGVPSP--QITWYKPGGQPITAG- 130 Query: 1492 RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529 PI + + A D G Y CRA NL+G+ E Sbjct: 131 -VSPISGGSQLQVTTTRE-AGDYGQYKCRAFNLLGSVE 166 Score = 32.3 bits (70), Expect = 9.9 Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 9/120 (7%) Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVS-----PPKIAQKPRNSKLQEGADAQFQVQ 288 V + +S+T+ G + E+ V P+I N+ Q + Sbjct: 49 VYYSDSVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKILSLQCK 108 Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS-DSGHYTLLAENPNGCI 347 G P P++TW+K G + I + I + L+V T+++ D G Y A N G + Sbjct: 109 ARGVPSPQITWYKPGGQPITAGVSPI---SGGSQLQVTTTREAGDYGQYKCRAFNLLGSV 165 >SB_56353| Best HMM Match : I-set (HMM E-Value=6.3e-15) Length = 157 Score = 49.2 bits (112), Expect = 8e-05 Identities = 42/133 (31%), Positives = 57/133 (42%), Gaps = 12/133 (9%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV---IEKEQVVAPKFVERFSTLNVREGE 506 L I T +G+ TC N+ +L V IE + + P+F + V EGE Sbjct: 31 LTIPYATRIHTGIYTCTGSNQYSYDQNSVQLRVAAPIEPQVSILPRF------MTVDEGE 84 Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566 V A G P+P I W G P P+ + +D L IP+AK + Y CTA+ Sbjct: 85 VVQFRCTASGFPSPVIQWL--GGPGGQLPKESVISDENR-VLTIPQAKKAHEGEYFCTAR 141 Query: 567 NVAGSTATRARLY 579 N G R LY Sbjct: 142 NEGGVGTMRTMLY 154 Score = 43.6 bits (98), Expect = 0.004 Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 6/114 (5%) Query: 4601 CVVSLPATKDKPKPQTK-AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659 C S + D+ Q + AA P++ + V EG+ ++F C G P P +QW G Sbjct: 46 CTGSNQYSYDQNSVQLRVAAPIEPQVSILPRFMTVDEGEVVQFRCTASGFPSPVIQWLGG 105 Query: 4660 DKLIKPSKYFQMSRTADE-YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 P + S +DE L I +A EG+Y C A N G T+ L V Sbjct: 106 PGGQLPKE----SVISDENRVLTIPQAKKAHEGEYFCTARNEGGVGTMRTMLYV 155 Score = 41.5 bits (93), Expect = 0.016 Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 13/153 (8%) Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708 K TV+W KG K PS T + L I A G Y C N + Sbjct: 5 KTYATVKWSKGLKGTLPS-----GATDKDGVLTIPYATRIHTGIYTCTGSNQYSYDQNSV 59 Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL-REGALIPETPDF 4767 +L+V P + ++ P R + V EG+ QF+ + P IQWL G +P+ Sbjct: 60 QLRVAAPIEPQ--VSILP-RFMTVDEGEVVQFRCTASGFPSPVIQWLGGPGGQLPK---- 112 Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 + + N VL I + G + C A G Sbjct: 113 ESVISDENRVLTIPQAKKAHEGEYFCTARNEGG 145 Score = 37.1 bits (82), Expect = 0.35 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 6/89 (6%) Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN-GQRLINSNKHEIIT 316 R P+ P +++ PR + EG QF+ SG P P + W G +L K +I+ Sbjct: 62 RVAAPIEP-QVSILPRFMTVDEGEVVQFRCTASGFPSPVIQWLGGPGGQL---PKESVIS 117 Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345 N L + +K+ G Y A N G Sbjct: 118 DENR-VLTIPQAKKAHEGEYFCTARNEGG 145 Score = 36.7 bits (81), Expect = 0.46 Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 15/128 (11%) Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK---PRFTTHIQNIEGLKD 3163 VL I +G Y+C +N++ + SV+L + Q PRF T + + Sbjct: 30 VLTIPYATRIHTGIYTCTGSNQYSYDQNSVQLRVAAPIEPQVSILPRFMT-------VDE 82 Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 G+ F CT P I+W G P + +SD V L I + GEY Sbjct: 83 GEVVQFRCTASGFPSP--VIQWL--GGPGGQLPKESVISDENRV-LTIPQAKKAHEGEYF 137 Query: 3224 CRAYNKYG 3231 C A N+ G Sbjct: 138 CTARNEGG 145 Score = 35.9 bits (79), Expect = 0.80 Identities = 14/30 (46%), Positives = 19/30 (63%) Query: 4116 LPDAVTVEEGEWARFCCRVTGHPKPRVMWL 4145 LP +TV+EGE +F C +G P P + WL Sbjct: 74 LPRFMTVDEGEVVQFRCTASGFPSPVIQWL 103 Score = 34.7 bits (76), Expect = 1.9 Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 8/85 (9%) Query: 72 PIFEQIFKNARFA---QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128 PI Q+ RF +G +F G P+PV+ W P + K S+ +E Sbjct: 66 PIEPQVSILPRFMTVDEGEVVQFRCTASGFPSPVIQWLG--GPGGQLPKESVISDENR-- 121 Query: 129 VSLLIKQIGPGDEGEYTCTARNQYG 153 L I Q EGEY CTARN+ G Sbjct: 122 -VLTIPQAKKAHEGEYFCTARNEGG 145 >SB_24015| Best HMM Match : I-set (HMM E-Value=2.7e-21) Length = 609 Score = 49.2 bits (112), Expect = 8e-05 Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 31/196 (15%) Query: 403 VTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT-LSDS 460 V E + C V TG Y TW +N + D H I N G L I +V+ L D Sbjct: 65 VREWESVELYCNVNTGAVY---TWTVNGSAVVLDDLHTI--NPLGT--LQIASVSKLRDV 117 Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTPT 519 G C+ARN +G A L + V PKF + E G+PV+ A G P Sbjct: 118 GEYVCIARNAAGFGAASLELYI-----GVRPKFKTLPVPVEADEPGKPVLFKCSADGYPN 172 Query: 520 PRITWQKDGVPI----IPNPELRIHTDGG------------ASTLDIPRAKASDAAWYQC 563 P I+W++DG+ I N + ++ +G +L I D Y C Sbjct: 173 PTISWKRDGLLITSSSTSNSQYQVTNEGALLYHGKKHFITKEGSLIIFDPSEDDEGSYTC 232 Query: 564 TAQNVAGSTATRARLY 579 A N G R LY Sbjct: 233 EAANEVGKAIHRITLY 248 Score = 48.0 bits (109), Expect = 2e-04 Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 24/188 (12%) Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689 K K+V E +++E C + + T W + ++ +S+ D Sbjct: 61 KKKLVREWESVELYCNVNTGAVYT--WTVNGSAVVLDDLHTINPLGTLQIASVSKL--RD 116 Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749 G+Y C+A N+AG + +L + + LP + G+P FK Sbjct: 117 VGEYVCIARNAAGFGAASLELYIGVRPKFKTLPVPVEADE----PGKPVLFKCSADGYPN 172 Query: 4750 PTIQWLREGALIPET----PDFQMIHEG------------NNAVLLIGNTYEEDTGTFTC 4793 PTI W R+G LI + +Q+ +EG L+I + E+D G++TC Sbjct: 173 PTISWKRDGLLITSSSTSNSQYQVTNEGALLYHGKKHFITKEGSLIIFDPSEDDEGSYTC 232 Query: 4794 RATTAAGQ 4801 A G+ Sbjct: 233 EAANEVGK 240 Score = 43.6 bits (98), Expect = 0.004 Identities = 46/173 (26%), Positives = 68/173 (39%), Gaps = 33/173 (19%) Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606 W NG V D + I GT + + +D G+Y C+A N+AG E + + Sbjct: 85 WTVNGSAVVLDDLHTI-NPLGTLQIASVSKL-RDVGEYVCIARNAAGFGAASLELYIGV- 141 Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666 +P+ K P E EP G+ + F C G P PT+ W + LI S Sbjct: 142 ------RPKFKTLPVPVEADEP--------GKPVLFKCSADGYPNPTISWKRDGLLITSS 187 Query: 4667 ----KYFQMSR------------TADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 +Q++ E +L I + +DEG Y C A N G+ Sbjct: 188 STSNSQYQVTNEGALLYHGKKHFITKEGSLIIFDPSEDDEGSYTCEAANEVGK 240 Score = 37.9 bits (84), Expect = 0.20 Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 20/118 (16%) Query: 1836 VEVAVNQAPRFITQLNGPTKLSE-GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH--- 1891 +E+ + P+F T L P + E G+ ++C + YP+P + W +G ++ S Sbjct: 135 LELYIGVRPKFKT-LPVPVEADEPGKPVLFKCSADGYPNPT--ISWKRDGLLITSSSTSN 191 Query: 1892 -RYRTSNDFGF------------AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 +Y+ +N+ +L I +D G YTC+A N +G+A+ I L V Sbjct: 192 SQYQVTNEGALLYHGKKHFITKEGSLIIFDPSEDDEGSYTCEAANEVGKAIHRITLYV 249 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 7/63 (11%) Query: 4111 PVFVSLPDAVTVEE-GEWARFCCRVTGHPKPRVMW----LLNGNTIVNGSRYKLTYDG-- 4163 P F +LP V +E G+ F C G+P P + W LL ++ + S+Y++T +G Sbjct: 143 PKFKTLPVPVEADEPGKPVLFKCSADGYPNPTISWKRDGLLITSSSTSNSQYQVTNEGAL 202 Query: 4164 MYH 4166 +YH Sbjct: 203 LYH 205 Score = 34.7 bits (76), Expect = 1.9 Identities = 13/25 (52%), Positives = 19/25 (76%) Query: 1778 EDSGTYTCRAINELGEAVTSSTLFV 1802 +D G+YTC A NE+G+A+ TL+V Sbjct: 225 DDEGSYTCEAANEVGKAIHRITLYV 249 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 14/80 (17%) Query: 91 FEGKLRGNPTPVVSWTRKKAPLVECNKYSMRY---NEQ-----------TGDVSLLIKQI 136 F+ G P P +SW R + + + +Y NE T + SL+I Sbjct: 163 FKCSADGYPNPTISWKRDGLLITSSSTSNSQYQVTNEGALLYHGKKHFITKEGSLIIFDP 222 Query: 137 GPGDEGEYTCTARNQYGEAI 156 DEG YTC A N+ G+AI Sbjct: 223 SEDDEGSYTCEAANEVGKAI 242 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 4/66 (6%) Query: 1079 WYFNGKQITSANRIQTYHDFGYVALDIASV-RAEDSGVYTVVARNAAGEAQLSASMTVET 1137 W NG + + + T + G L IASV + D G Y +ARNAAG S + + Sbjct: 85 WTVNGSAVV-LDDLHTINPLG--TLQIASVSKLRDVGEYVCIARNAAGFGAASLELYIGV 141 Query: 1138 RSSIDT 1143 R T Sbjct: 142 RPKFKT 147 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 6/71 (8%) Query: 2951 GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLI 3010 G +L G + +T + + + D E D G YTC+A N+ G+A T+Y D + Sbjct: 200 GALLYHGKKHFITKEGSLI---IFDPSEDDEGSYTCEAANEVGKAIHRITLYV---DITL 253 Query: 3011 ERTQHPKGTEG 3021 H KG G Sbjct: 254 NTHAHYKGGGG 264 Score = 32.3 bits (70), Expect = 9.9 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 8/95 (8%) Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615 +P T +P ++ E S C VN ++ W NG ++ + TIN G Sbjct: 52 DPVVVTVSPKKKLVREWESVELYCN---VNTGAVYT-WTVNGSAVVLDD-LHTINPLG-- 104 Query: 3616 ILEIGGVYQ-RDAGLYTCKATNRHGEATVSCKLQV 3649 L+I V + RD G Y C A N G S +L + Sbjct: 105 TLQIASVSKLRDVGEYVCIARNAAGFGAASLELYI 139 >SB_52866| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1376 Score = 49.2 bits (112), Expect = 8e-05 Identities = 43/166 (25%), Positives = 67/166 (40%), Gaps = 17/166 (10%) Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE--SGNHALMITNVTLS 458 R ++ GK C ++G + W+ +I D + V+ SG + L + N+ ++ Sbjct: 230 RVISAGKNLVIKCTISGEQFQG--WYRGGSKIPTDSSQTKYVSNPTSGAYQLHLNNIVVA 287 Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518 D G C R G FQ ++ VE L + + + ++ G P Sbjct: 288 DGGEYIC--RGNRGSKTFQLYVDFTTTH-------VELIQYLRISNADMIDIDV--YGYP 336 Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 P W K+G P PN E R T G S + R + SD Y CT Sbjct: 337 KPTFVWTKNGQPWNPN-EGRFSTQDGGS-VKFSRVEISDQGNYTCT 380 Score = 43.6 bits (98), Expect = 0.004 Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 11/159 (6%) Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC-VAYNSAGRV 4704 + G P PT W K + P++ T D +++ S D+G+Y C +A ++ G Sbjct: 332 VYGYPKPTFVWTKNGQPWNPNE--GRFSTQDGGSVKFSRVEISDQGNYTCTIAVDTLGLS 389 Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764 +V K++V + P++ P+ D VV + A P ++W+R+G Sbjct: 390 SVK-KIEVITFVR----PSIKPMYDEVVEIDEQAYLDCVGEGNPLPEVRWIRDGRYERRQ 444 Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803 Q+ G + + I + ED G +TC A A E Sbjct: 445 ---QITLGGRRSRIYIQDVRLEDEGRYTCEARNNARDQE 480 Score = 41.5 bits (93), Expect = 0.016 Identities = 42/182 (23%), Positives = 76/182 (41%), Gaps = 24/182 (13%) Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580 Q + +++ ++ +D V G W KNG+ P+ ++ G+ +E D Sbjct: 318 QYLRISNADMIDID--VYGYPKPTFVWTKNGQPWNPNEGRFSTQDGGSVKFSRVEI--SD 373 Query: 4581 SGKYEC-VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 G Y C +A+++ G + V++ +P I+P+ D++V + Sbjct: 374 QGNYTCTIAVDTLGLSSVKKIEVITFV------RPS----------IKPMYDEVVEIDEQ 417 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 C G PLP V+W + + + + R + Y I + EDEG Y C A N Sbjct: 418 AYLDCVGEGNPLPEVRWIRDGRYERRQQITLGGRRSRIY---IQDVRLEDEGRYTCEARN 474 Query: 4700 SA 4701 +A Sbjct: 475 NA 476 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 6/78 (7%) Query: 395 VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMIT 453 +K D V + DC G P PEV W + R Y + + G + + I Sbjct: 404 IKPMYDEVVEIDEQAYLDCVGEGNPLPEVRWIRDGR-----YERRQQITLGGRRSRIYIQ 458 Query: 454 NVTLSDSGVVTCVARNKS 471 +V L D G TC ARN + Sbjct: 459 DVRLEDEGRYTCEARNNA 476 Score = 35.9 bits (79), Expect = 0.80 Identities = 38/158 (24%), Positives = 58/158 (36%), Gaps = 10/158 (6%) Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471 D V G P P W N + + + + G+ + + V +SD G TC + Sbjct: 329 DIDVYGYPKPTFVWTKNGQPWNPNEG-RFSTQDGGS--VKFSRVEISDQGNYTCTI---A 382 Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531 +T + IE V P + + V E L+ G P P + W +DG Sbjct: 383 VDTLGLSSVKKIEVITFVRPSIKPMYDEV-VEIDEQAYLDCVGEGNPLPEVRWIRDG--- 438 Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 +I G S + I + D Y C A+N A Sbjct: 439 RYERRQQITLGGRRSRIYIQDVRLEDEGRYTCEARNNA 476 Score = 32.7 bits (71), Expect = 7.5 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 7/87 (8%) Query: 2369 EPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428 E +T RP + I E A+ DC + G+P +V W R+ + E +IT Sbjct: 395 EVITFVRPSIKPMYDEVVEIDE--QAYLDC--VGEGNPLPEVRWIRDGRY-ERRQQITLG 449 Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASN 2455 + I VR EDEG Y C A N Sbjct: 450 GRRSRIY--IQDVRLEDEGRYTCEARN 474 >SB_8401| Best HMM Match : ig (HMM E-Value=8.1e-22) Length = 965 Score = 48.8 bits (111), Expect = 1e-04 Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 13/125 (10%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L I +V D+G + + GET F+ ++ V+ P V + + V + V Sbjct: 675 LTIKDVQPQDAGEYAMILSDNGGETTFEASKFTLD---VLVPPSVTH-ANITVNKTNTAV 730 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 L A G PTP +TW + G + G TL SD Y CTA N Sbjct: 731 LMCSATGNPTPNVTWTRSG---------KEDVLGTGETLTFSDVNISDGGCYVCTATNNI 781 Query: 570 GSTAT 574 GS A+ Sbjct: 782 GSGAS 786 Score = 36.3 bits (80), Expect = 0.61 Identities = 39/146 (26%), Positives = 62/146 (42%), Gaps = 20/146 (13%) Query: 436 YNHKILVNESGNHALMITNVTLSDSGV--VTCVARNKSGETAFQC-RLNVIEKEQVVAPK 492 Y +L+ ++ N M N+ L G+ +TCV N +G + +NV EK ++ Sbjct: 807 YMDNLLIKKNING--MFHNILLDSVGIHLLTCVPINDAGVGENRSVSMNVTEKLPTIS-- 862 Query: 493 FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552 +T+N EG VV A+G + + W+KDGV G S+L + Sbjct: 863 ITPLRATVN--EGSVVVFTCLAIGFQSFKNFWKKDGV-----------FKGDGSSLMLSS 909 Query: 553 AKASDAAWYQCTAQNVAGSTATRARL 578 D+ Y C + G+T A L Sbjct: 910 VGRDDSGNYTCNVTSTCGTTMKTASL 935 Score = 35.1 bits (77), Expect = 1.4 Identities = 14/34 (41%), Positives = 22/34 (64%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +L ++S+ DDSG YTC T+ G + TAS+ + Sbjct: 904 SLMLSSVGRDDSGNYTCNVTSTCGTTMKTASLDV 937 Score = 34.7 bits (76), Expect = 1.9 Identities = 35/136 (25%), Positives = 54/136 (39%), Gaps = 20/136 (14%) Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 L I+ V +D+ +A + + GG A+ + +VPPS +T N+ V Sbjct: 675 LTIKDVQPQDAGEYAMILSDNGGETTFEASKFTLDV-------LVPPS--VTHANITVNK 725 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLILEAYPQDSGKYEC 4586 L TG +V W ++GK+ D+ GT TL + D G Y C Sbjct: 726 TNTAVLMCSATGNPTPNVTWTRSGKE---DVL-------GTGETLTFSDVNISDGGCYVC 775 Query: 4587 VAINSAGEARCDAECV 4602 A N+ G C+ Sbjct: 776 TATNNIGSGASGTVCL 791 Score = 34.3 bits (75), Expect = 2.5 Identities = 34/135 (25%), Positives = 50/135 (37%), Gaps = 13/135 (9%) Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725 S+Y + T + TL I + P+D G+Y + ++ G T A K T P++T Sbjct: 661 SRYSLSTATFNPITLTIKDVQPQDAGEYAMILSDNGGETTFEAS-KFTLDVLVP--PSVT 717 Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785 +I V + A T P + W R G D G L + Sbjct: 718 H-ANITVNKTNTAVLMCSATGNPTPNVTWTRSG-----KEDVL----GTGETLTFSDVNI 767 Query: 4786 EDTGTFTCRATTAAG 4800 D G + C AT G Sbjct: 768 SDGGCYVCTATNNIG 782 Score = 32.7 bits (71), Expect = 7.5 Identities = 15/42 (35%), Positives = 21/42 (50%) Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161 +TV + A C TG+P P V W +G V G+ LT+ Sbjct: 721 ITVNKTNTAVLMCSATGNPTPNVTWTRSGKEDVLGTGETLTF 762 >SB_21597| Best HMM Match : ig (HMM E-Value=2.9e-14) Length = 1931 Score = 48.8 bits (111), Expect = 1e-04 Identities = 51/191 (26%), Positives = 70/191 (36%), Gaps = 20/191 (10%) Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674 QT A+AP P A G+ + SC V P+P W K D P + Sbjct: 1390 QTYCASAPAITTHPQPLTETAAGKPLRLSCAAVATPMPAYYWVK-DGARLPGQ------- 1441 Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD--IVV 4732 + L I E PED G Y CVAYN V + + ++P LT + V Sbjct: 1442 -NGSELIIIELKPEDNGTYICVAYNH-----VTSSKSASGHVIVHSVPVLTKQSSDHVTV 1495 Query: 4733 YEGQPAQFKTQITSKIKP-TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791 G T P T QW R P TP + + +L I + + G + Sbjct: 1496 PVGGDVSLSVWATGTDLPLTYQWYRRD---PITPQYTPLSNEIYPMLTIHSARAQHQGGY 1552 Query: 4792 TCRATTAAGQV 4802 C+ + G V Sbjct: 1553 RCQVSNRYGDV 1563 Score = 44.8 bits (101), Expect = 0.002 Identities = 51/194 (26%), Positives = 83/194 (42%), Gaps = 30/194 (15%) Query: 4514 PSFTLTAQNVNVTS-GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 P+ T Q + T+ G+ +RL T YW+K+G ++ ++G+ L+ Sbjct: 1397 PAITTHPQPLTETAAGKPLRLSCAAVATPMPAYYWVKDGARLPG--------QNGS-ELI 1447 Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632 I+E P+D+G Y CVA N ++ + V+ ++ P + + D Sbjct: 1448 IIELKPEDNGTYICVAYNHVTSSKSASGHVI---------------VHSVPVLTKQSSDH 1492 Query: 4633 I-VAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 + V G + S G LP T QWY+ D I P +Y +S L I A + + Sbjct: 1493 VTVPVGGDVSLSVWATGTDLPLTYQWYRRDP-ITP-QYTPLSNEIYP-MLTIHSARAQHQ 1549 Query: 4691 GDYKCVAYNSAGRV 4704 G Y+C N G V Sbjct: 1550 GGYRCQVSNRYGDV 1563 Score = 34.3 bits (75), Expect = 2.5 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%) Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT-SGIAIVHSKKSIYLE 1678 +K G+R N + +++ PED+GTY C A N + + + SG IVHS + + Sbjct: 1432 VKDGARLPGQNGSELIIIELK---PEDNGTYICVAYNHVTSSKSASGHVIVHSVPVLTKQ 1488 Query: 1679 SQHEGALP 1686 S +P Sbjct: 1489 SSDHVTVP 1496 >SB_52846| Best HMM Match : ig (HMM E-Value=9e-12) Length = 330 Score = 48.4 bits (110), Expect = 1e-04 Identities = 54/240 (22%), Positives = 97/240 (40%), Gaps = 15/240 (6%) Query: 4578 PQD-SGKYECVAINSAGEARCDAECVVSLPATKDKPK-PQTKAANAPPEIIEPL-KDKIV 4634 P+D SG+ ++ S + +C+V K + + Q K P I++P K I Sbjct: 33 PEDKSGRNLIISQVSKEQHEGVYQCIVENNQGKTESQLSQLKVFVPPGWIVKPPPKMNIP 92 Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694 G A+ C+ G P P WY I S++ + T ++ T + E + E G Y+ Sbjct: 93 MYGGAV-LLCEAFGDPTPAYGWYVNGSKIVNSQHLIV--TNNKLTFKAVELY-EHAGIYQ 148 Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754 CVA N G V +++ P + +++ + K + W Sbjct: 149 CVAENDYGMVVSTTVVEIDA-----RKPGIIGFGPFYIFKDTKGEIKCDSNAAPAANHVW 203 Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 ++ ++ + + + GN+ L+I + D G +TC+AT G S V +T Sbjct: 204 SKDDQVLSISGRYSL-GPGNS--LVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYERT 260 Score = 44.0 bits (99), Expect = 0.003 Identities = 34/131 (25%), Positives = 58/131 (44%), Gaps = 9/131 (6%) Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870 + QHE Q I + + ++V V P +I + P K++ E Sbjct: 48 KEQHEGVYQCIVENNQGKTESQLSQLKVFV--PPGWIVK--PPPKMNIPMYGGAVLLCEA 103 Query: 1871 YPDPNMRVEWYFNG-KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929 + DP WY NG K++ S H T+N F A+++ E +G Y C A N+ G V Sbjct: 104 FGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVELY----EHAGIYQCVAENDYGMVV 159 Query: 1930 SSIRLNVQSKE 1940 S+ + + +++ Sbjct: 160 STTVVEIDARK 170 Score = 42.7 bits (96), Expect = 0.007 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 V P I + P + A + G+P P W+ NG +++NS +I T+N T Sbjct: 77 VPPGWIVKPPPKMNIPMYGGAVLLCEAFGDPTPAYGWYVNGSKIVNS--QHLIVTNNKLT 134 Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 + + +G Y +AEN G +V++ + +++ Sbjct: 135 FKAVELYE-HAGIYQCVAENDYGMVVSTTVVEIDA 168 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 5/68 (7%) Query: 2006 DPTMRVEWYCNG-RPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064 DPT WY NG + V H T + A++ LY +A G Y C A N G V+T Sbjct: 106 DPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVE-LYEHA---GIYQCVAENDYGMVVST 161 Query: 2065 SSVKVDAK 2072 + V++DA+ Sbjct: 162 TVVEIDAR 169 Score = 39.5 bits (88), Expect = 0.065 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 7/99 (7%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGF 3752 PP + V+ +++P G C E GDPT W+ NG + T N F Sbjct: 78 PPGWIVKPPPKMNIPMYGGAVLLC--EAFGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTF 135 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791 A+++ AG Y C A N +G +T + A++ Sbjct: 136 KAVEL----YEHAGIYQCVAENDYGMVVSTTVVEIDARK 170 Score = 35.9 bits (79), Expect = 0.80 Identities = 39/147 (26%), Positives = 61/147 (41%), Gaps = 12/147 (8%) Query: 428 NDR-QIRDDYNHKILVNESGNHALMITNVTLSD-SGVVTCVARNKSGETAFQCRLNVIEK 485 ND+ I D N + + L+I+ V+ GV C+ N G+T Q + + Sbjct: 18 NDKLPIVDGKNGFSIPEDKSGRNLIISQVSKEQHEGVYQCIVENNQGKTESQ-----LSQ 72 Query: 486 EQVVAPK--FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543 +V P V+ +N+ VL A G PTP W +G I+ N + I T+ Sbjct: 73 LKVFVPPGWIVKPPPKMNIPMYGGAVLLCEAFGDPTPAYGWYVNGSKIV-NSQHLIVTNN 131 Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAG 570 + + + A YQC A+N G Sbjct: 132 KLTFKAVELYE--HAGIYQCVAENDYG 156 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Query: 2134 EPINDPHLTIDWFHNGQKI-RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE 2192 E DP W+ NG KI + H T + + A++ LY +A G Y C A N G Sbjct: 102 EAFGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVE-LYEHA---GIYQCVAENDYGM 157 Query: 2193 AVNTCTLKV 2201 V+T +++ Sbjct: 158 VVSTTVVEI 166 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 1338 GDQTMRVEWFCNG-KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396 GD T W+ NG K + + H + + A++L E +G+Y C A N G V+ Sbjct: 105 GDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVELY----EHAGIYQCVAENDYGMVVS 160 Query: 1397 SCALRVIAKKDLIL 1410 + + + A+K I+ Sbjct: 161 TTVVEIDARKPGII 174 Score = 34.3 bits (75), Expect = 2.5 Identities = 15/37 (40%), Positives = 22/37 (59%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 +L I ++ +D G YTCKATNLLG + + +R Sbjct: 223 SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 259 Score = 33.9 bits (74), Expect = 3.2 Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 6/114 (5%) Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019 TE L + PP ++ + + ++ C+ GDP W+ NG +++ Sbjct: 66 TESQLSQLKVFVPPGWIVKPPPKMNIPMYGGAVLLCEA--FGDPTPAYGWYVNGSKIVNS 123 Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG-KPGIV 4072 I + +Y E +G Y C A N YGM + V++ KPGI+ Sbjct: 124 QHL--IVTNNKLTFKAVELY-EHAGIYQCVAENDYGMVVSTTVVEIDARKPGII 174 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Query: 945 WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 W KD + + S R + G +L I V +D G YTC+A N +G T S + T+ + Sbjct: 203 WSKDDQVLSISGRYS--LGPGN-SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 259 Query: 1005 KDI 1007 I Sbjct: 260 TKI 262 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/66 (34%), Positives = 27/66 (40%) Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676 L I V Q D G YTCKATN G T S V R I + P G + + + Sbjct: 224 LVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYERTKITVRPDASVELIKGKPTDFRCQ 283 Query: 3677 ETLHKR 3682 T R Sbjct: 284 ATADPR 289 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539 W K+ Q ++I R+ V I + D G YTC+A NL+GTD S T Sbjct: 203 WSKDDQVLSISGRYSLGPGNSLV---ITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 259 Query: 1540 TDIVRSTQNEAGLEQIQ 1556 T I + + +A +E I+ Sbjct: 260 TKI--TVRPDASVELIK 274 Score = 33.1 bits (72), Expect = 5.7 Identities = 16/29 (55%), Positives = 18/29 (62%) Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSATTS 2860 SL IT + D G YTCKATN G+ T S Sbjct: 223 SLVITPVQQNDEGKYTCKATNLLGTDTKS 251 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 8/102 (7%) Query: 632 RVYPPPQFIV--PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689 +V+ PP +IV P K M GG + E GDPT W NG I S I Sbjct: 74 KVFVPPGWIVKPPPKMNIPMYGGAVLL---CEAFGDPTPAYGWYVNGSKIVNSQHL--IV 128 Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 ++ + L + +G Y C A + G+ + V+ + R Sbjct: 129 TNNKLTFKAVEL-YEHAGIYQCVAENDYGMVVSTTVVEIDAR 169 Score = 32.7 bits (71), Expect = 7.5 Identities = 13/24 (54%), Positives = 18/24 (75%) Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458 S+ I+ V+ DEG Y C+A+NLLG Sbjct: 223 SLVITPVQQNDEGKYTCKATNLLG 246 Score = 32.3 bits (70), Expect = 9.9 Identities = 36/160 (22%), Positives = 61/160 (38%), Gaps = 14/160 (8%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVVTCVARNKS 471 C G P P W++N +I + H I+ N+ L V L + +G+ CVA N Sbjct: 101 CEAFGDPTPAYGWYVNGSKIVNS-QHLIVT----NNKLTFKAVELYEHAGIYQCVAENDY 155 Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531 G V+E + P + F + + + + P W KD + Sbjct: 156 GMVV---STTVVEID-ARKPGII-GFGPFYIFKDTKGEIKCDSNAAPAANHVWSKDDQVL 210 Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571 + + G ++L I + +D Y C A N+ G+ Sbjct: 211 SISGRYSL---GPGNSLVITPVQQNDEGKYTCKATNLLGT 247 >SB_12096| Best HMM Match : ig (HMM E-Value=9.4e-33) Length = 942 Score = 48.4 bits (110), Expect = 1e-04 Identities = 54/240 (22%), Positives = 97/240 (40%), Gaps = 15/240 (6%) Query: 4578 PQD-SGKYECVAINSAGEARCDAECVVSLPATKDKPK-PQTKAANAPPEIIEPL-KDKIV 4634 P+D SG+ ++ S + +C+V K + + Q K P I++P K I Sbjct: 617 PEDKSGRNLIISQVSKEQHEGVYQCIVENNQGKTESQLSQLKVFVPPGWIVKPPPKMNIP 676 Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694 G A+ C+ G P P WY I S++ + T ++ T + E + E G Y+ Sbjct: 677 MYGGAV-LLCEAFGDPTPAYGWYVNGSKIVNSQHLIV--TNNKLTFKAVELY-EHAGIYQ 732 Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754 CVA N G V +++ P + +++ + K + W Sbjct: 733 CVAENDYGMVVSTTVVEIDA-----RKPGIIGFGPFYIFKDTKGEIKCDSNAAPAANHVW 787 Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 ++ ++ + + + GN+ L+I + D G +TC+AT G S V +T Sbjct: 788 SKDDQVLSISGRYSL-GPGNS--LVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYERT 844 Score = 44.0 bits (99), Expect = 0.003 Identities = 34/131 (25%), Positives = 58/131 (44%), Gaps = 9/131 (6%) Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870 + QHE Q I + + ++V V P +I + P K++ E Sbjct: 632 KEQHEGVYQCIVENNQGKTESQLSQLKVFV--PPGWIVK--PPPKMNIPMYGGAVLLCEA 687 Query: 1871 YPDPNMRVEWYFNG-KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929 + DP WY NG K++ S H T+N F A+++ E +G Y C A N+ G V Sbjct: 688 FGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVELY----EHAGIYQCVAENDYGMVV 743 Query: 1930 SSIRLNVQSKE 1940 S+ + + +++ Sbjct: 744 STTVVEIDARK 754 Score = 42.7 bits (96), Expect = 0.007 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 V P I + P + A + G+P P W+ NG +++NS +I T+N T Sbjct: 661 VPPGWIVKPPPKMNIPMYGGAVLLCEAFGDPTPAYGWYVNGSKIVNS--QHLIVTNNKLT 718 Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 + + +G Y +AEN G +V++ + +++ Sbjct: 719 FKAVELYE-HAGIYQCVAENDYGMVVSTTVVEIDA 752 Score = 42.7 bits (96), Expect = 0.007 Identities = 67/266 (25%), Positives = 105/266 (39%), Gaps = 35/266 (13%) Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV-FVEDSAVFAAVAENRGGTAKC 4494 G+P P WY I NS H T + L + V E + ++ VAEN G Sbjct: 689 GDPTPAYGWYVNGSKIVNSQ----HLIVTNNKLTFKAVELYEHAGIYQCVAENDYGMV-V 743 Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554 S +V + R+ G G P F + T G+ ++ D+ + W K+ + + Sbjct: 744 STTVVEIDARKPGIIGFGP--FYIFKD----TKGE-IKCDSNAAPAA--NHVWSKDDQVL 794 Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614 I + G +L+I D GKY C A N G + V Sbjct: 795 S--ISGRYSLGPGN-SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVY---------E 842 Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP-LPTVQWYKGDKLIKPSKYFQ-MS 4672 +TK P +E +K G+ +F C+ P L + YK K +Y + ++ Sbjct: 843 RTKITVRPDASVELIK------GKPTDFRCQATADPRLMNILKYKWLKDGTELQYTENIN 896 Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAY 4698 ++ L++SEA +D Y CVAY Sbjct: 897 WIPNQLRLKLSEADIDDGAVYTCVAY 922 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 5/68 (7%) Query: 2006 DPTMRVEWYCNG-RPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064 DPT WY NG + V H T + A++ LY +A G Y C A N G V+T Sbjct: 690 DPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVE-LYEHA---GIYQCVAENDYGMVVST 745 Query: 2065 SSVKVDAK 2072 + V++DA+ Sbjct: 746 TVVEIDAR 753 Score = 39.5 bits (88), Expect = 0.065 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 7/99 (7%) Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGF 3752 PP + V+ +++P G C E GDPT W+ NG + T N F Sbjct: 662 PPGWIVKPPPKMNIPMYGGAVLLC--EAFGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTF 719 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791 A+++ AG Y C A N +G +T + A++ Sbjct: 720 KAVEL----YEHAGIYQCVAENDYGMVVSTTVVEIDARK 754 Score = 36.7 bits (81), Expect = 0.46 Identities = 20/66 (30%), Positives = 39/66 (59%), Gaps = 4/66 (6%) Query: 4533 LDTKVTGTKPIDVYWLKNGKKV-QPDIRNKIL--EEDGTYTLLILEAYP-QDSGKYECVA 4588 L+ + +G PI +YW K+GK + + + + +I+ ++ G L + P QD+G ++C A Sbjct: 354 LECRASGKTPITMYWEKDGKLLAELEFKYEIITDKQKGVSKLKVQIPRPSQDNGNFQCFA 413 Query: 4589 INSAGE 4594 N+ G+ Sbjct: 414 ENAEGK 419 Score = 36.7 bits (81), Expect = 0.46 Identities = 51/213 (23%), Positives = 83/213 (38%), Gaps = 22/213 (10%) Query: 372 TDTQQRETEERIEISEKALAPQFVKVCQDRDVT---EGKMTRFDCRVTGRPYPE--VTWF 426 T T + +++ L P FV+ + + + +GK C P P + W Sbjct: 536 TYTSHKFLLKQVGTDNSPLKPVFVQDGEPKTLESAIQGKSKALFCVAQMSPAPNNAIRWV 595 Query: 427 -----INDR-QIRDDYNHKILVNESGNHALMITNVTLSD-SGVVTCVARNKSGETAFQCR 479 ND+ I D N + + L+I+ V+ GV C+ N G+T Q Sbjct: 596 RVDSVTNDKLPIVDGKNGFSIPEDKSGRNLIISQVSKEQHEGVYQCIVENNQGKTESQ-- 653 Query: 480 LNVIEKEQVVAPK--FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537 + + +V P V+ +N+ VL A G PTP W +G I+ N + Sbjct: 654 ---LSQLKVFVPPGWIVKPPPKMNIPMYGGAVLLCEAFGDPTPAYGWYVNGSKIV-NSQH 709 Query: 538 RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 I T+ + + + A YQC A+N G Sbjct: 710 LIVTNNKLTFKAVELYE--HAGIYQCVAENDYG 740 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Query: 2134 EPINDPHLTIDWFHNGQKI-RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE 2192 E DP W+ NG KI + H T + + A++ LY +A G Y C A N G Sbjct: 686 EAFGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVE-LYEHA---GIYQCVAENDYGM 741 Query: 2193 AVNTCTLKV 2201 V+T +++ Sbjct: 742 VVSTTVVEI 750 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 1338 GDQTMRVEWFCNG-KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396 GD T W+ NG K + + H + + A++L E +G+Y C A N G V+ Sbjct: 689 GDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVELY----EHAGIYQCVAENDYGMVVS 744 Query: 1397 SCALRVIAKKDLIL 1410 + + + A+K I+ Sbjct: 745 TTVVEIDARKPGII 758 Score = 34.3 bits (75), Expect = 2.5 Identities = 15/37 (40%), Positives = 22/37 (59%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737 +L I ++ +D G YTCKATNLLG + + +R Sbjct: 807 SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 843 Score = 34.3 bits (75), Expect = 2.5 Identities = 33/139 (23%), Positives = 55/139 (39%), Gaps = 13/139 (9%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I + D G Y+C+ATN G + D + ++ + T L G+ Sbjct: 808 LVITPVQQNDEGKYTCKATNLLG-----TDTKSNDATVYERTKITVRPDASVELIKGKPT 862 Query: 3168 HFEC--TVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225 F C T P +K +W +G ++++ I + + + L ++ D Y C Sbjct: 863 DFRCQATADPRLMNILKYKWLKDGTELQYTENINWIPN--QLRLKLSEADIDDGAVYTCV 920 Query: 3226 AYN----KYGEDFTRATIN 3240 AY KY ED + N Sbjct: 921 AYTDDKLKYSEDRASSIAN 939 Score = 33.9 bits (74), Expect = 3.2 Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 6/114 (5%) Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019 TE L + PP ++ + + ++ C+ GDP W+ NG +++ Sbjct: 650 TESQLSQLKVFVPPGWIVKPPPKMNIPMYGGAVLLCEA--FGDPTPAYGWYVNGSKIVNS 707 Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG-KPGIV 4072 I + +Y E +G Y C A N YGM + V++ KPGI+ Sbjct: 708 QHL--IVTNNKLTFKAVELY-EHAGIYQCVAENDYGMVVSTTVVEIDARKPGII 758 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 3/63 (4%) Query: 945 WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004 W KD + + S R + G +L I V +D G YTC+A N +G T S + T+ + Sbjct: 787 WSKDDQVLSISGRYS--LGPGN-SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 843 Query: 1005 KDI 1007 I Sbjct: 844 TKI 846 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/66 (34%), Positives = 27/66 (40%) Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676 L I V Q D G YTCKATN G T S V R I + P G + + + Sbjct: 808 LVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYERTKITVRPDASVELIKGKPTDFRCQ 867 Query: 3677 ETLHKR 3682 T R Sbjct: 868 ATADPR 873 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECK--LEPVTDSNLKVEWFKNGQPVTIGHRFR 1494 D +V + + RP + +I+G+ F C+ +P + LK +W K+G + Sbjct: 837 DATVYERTKITVRPDASVELIKGKPTDFRCQATADPRLMNILKYKWLKDGTELQYTENIN 896 Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRA 1521 I + + L + + +D +YTC A Sbjct: 897 WIPN--QLRLKLSEADIDDGAVYTCVA 921 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539 W K+ Q ++I R+ V I + D G YTC+A NL+GTD S T Sbjct: 787 WSKDDQVLSISGRYSLGPGNSLV---ITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 843 Query: 1540 TDIVRSTQNEAGLEQIQ 1556 T I + + +A +E I+ Sbjct: 844 TKI--TVRPDASVELIK 858 Score = 33.1 bits (72), Expect = 5.7 Identities = 16/29 (55%), Positives = 18/29 (62%) Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSATTS 2860 SL IT + D G YTCKATN G+ T S Sbjct: 807 SLVITPVQQNDEGKYTCKATNLLGTDTKS 835 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 8/102 (7%) Query: 632 RVYPPPQFIV--PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689 +V+ PP +IV P K M GG + E GDPT W NG I S I Sbjct: 658 KVFVPPGWIVKPPPKMNIPMYGGAVLL---CEAFGDPTPAYGWYVNGSKIVNSQHL--IV 712 Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731 ++ + L + +G Y C A + G+ + V+ + R Sbjct: 713 TNNKLTFKAVEL-YEHAGIYQCVAENDYGMVVSTTVVEIDAR 753 Score = 32.7 bits (71), Expect = 7.5 Identities = 13/24 (54%), Positives = 18/24 (75%) Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458 S+ I+ V+ DEG Y C+A+NLLG Sbjct: 807 SLVITPVQQNDEGKYTCKATNLLG 830 >SB_26137| Best HMM Match : Plasmodium_HRP (HMM E-Value=0.27) Length = 271 Score = 48.0 bits (109), Expect = 2e-04 Identities = 35/182 (19%), Positives = 82/182 (45%), Gaps = 5/182 (2%) Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279 +T + +TE E E+ E+ +++ + + + + +E E E ++ +R+K E Sbjct: 77 QTEKEAQTEKEAER--EKEAETEKEAQTEKEAQTEKEAEREKEAETEKEAEREKEAEREI 134 Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339 + + + + KE++ + G + + T ++ ++ + + + E + +K Sbjct: 135 EAETEKEAETEKEAQTEKEAQTEKEAGTEKEAQTEKEAQMEKEAETEKEAQTEKEAQTEK 194 Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITR-KITSTE-TTEIEHKAQTQ 4397 + ++ E+ KE K+ QT+KE KE + K TE E E +A+T+ Sbjct: 195 EAEREKEAETEKEAKTE-KEAETEKEAQTEKEAETQKEAEKQKEAETEKEAETEKEAETE 253 Query: 4398 ER 4399 ++ Sbjct: 254 KK 255 Score = 42.7 bits (96), Expect = 0.007 Identities = 37/179 (20%), Positives = 70/179 (39%), Gaps = 3/179 (1%) Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279 E + + ETE E E+ +++ + E + + +E E E + + +K E Sbjct: 87 EAEREKEAETEKEAQTEKEAQTEKEAEREKEAETEKEAEREKEAEREIEAETEKEAETEK 146 Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339 + Q + Q KE+ + + + T ++ ++ + E E +K Sbjct: 147 EAQTEKEAQTEKEAGTEKEAQTEKEAQMEKEAETEKEAQTEKEAQTEKEAEREKEAETEK 206 Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEI-TRKITSTET-TEIEHKAQT 4396 + + E+ KE K+ + QKE +KE T K TE E E +A+T Sbjct: 207 EAKTEKEAETEKEAQTE-KEAETQKEAEKQKEAETEKEAETEKEAETEKKAETEKEAET 264 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 3/96 (3%) Query: 4305 PGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAK 4364 PG++V+ N + M E ++ + ++ ++K + + + KE K Sbjct: 58 PGNQVSRNG-REGMGTEKEAQTEKEAQTEKEAEREKEAETEKEAQTEKEAQTEKEAEREK 116 Query: 4365 QKQTQKEVVGDKEITRKI-TSTE-TTEIEHKAQTQE 4398 + +T+KE +KE R+I TE E E +AQT++ Sbjct: 117 EAETEKEAEREKEAEREIEAETEKEAETEKEAQTEK 152 >SB_2034| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1003 Score = 48.0 bits (109), Expect = 2e-04 Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 9/118 (7%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L+I N+ SD C+A+N GE + + + I ++ V+ + + G+ Sbjct: 122 LVIKNLQTSDVASYKCLAKNNIGEISAEVEVTRISEQAVITSDIKDATKVV----GDAFE 177 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 + A G + W+++G P + + G S + I K SDAA + CTA N Sbjct: 178 VACEATGASPLSVEWKRNGSPYLGQEK-----SNGKSVIKIQSLKLSDAAQFTCTASN 230 Score = 43.6 bits (98), Expect = 0.004 Identities = 58/249 (23%), Positives = 90/249 (36%), Gaps = 39/249 (15%) Query: 4560 NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619 +K + DG L+I D Y+C+A N+ GE + E Sbjct: 113 SKYVMNDGC--LVIKNLQTSDVASYKCLAKNNIGEISAEVEVT---------------RI 155 Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679 + I +KD G A E +C+ G +V+W + S Y ++ + Sbjct: 156 SEQAVITSDIKDATKVVGDAFEVACEATGASPLSVEWKRNG-----SPYLGQEKSNGKSV 210 Query: 4680 LRISEAFPEDEGDYKCVAYNSA---GRVTVAA---KLKVTQPDQADNLPALTPLRDIVVY 4733 ++I D + C A N G+ V+ KL V P + TPL V Sbjct: 211 IKIQSLKLSDAAQFTCTASNGLQFNGKDVVSTKSFKLTVEAPPTVVLEGSKTPLHSF-VG 269 Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIGNTYEEDTGTFT 4792 P K Q T PT+ ++G + + +GN A L + + D GTF Sbjct: 270 NTIPVTIKCQFTGLPMPTVVMTKDG---------KEVAKGNGTAQLDVVTSVTSDFGTFI 320 Query: 4793 CRATTAAGQ 4801 C A G+ Sbjct: 321 CEANNKRGR 329 Score = 39.1 bits (87), Expect = 0.086 Identities = 52/248 (20%), Positives = 87/248 (35%), Gaps = 28/248 (11%) Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527 L+I+ + D A + +A+N G + SA + V Q T ++ Sbjct: 122 LVIKNLQTSDVASYKCLAKNNIG--EISAEVEVTRISEQA-------VITSDIKDATKVV 172 Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587 G + + TG P+ V W +NG P + + + +G + I D+ ++ C Sbjct: 173 GDAFEVACEATGASPLSVEWKRNG---SPYLGQE--KSNGKSVIKIQSLKLSDAAQFTCT 227 Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647 A N D S T + P + P V + C+ Sbjct: 228 ASNGLQFNGKDVVSTKSFKLTVEAPPTVVLEGSKTP------LHSFVGNTIPVTIKCQFT 281 Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707 G P+PTV K K ++++ L + + D G + C A N GR Sbjct: 282 GLPMPTVVMTKDGK--------EVAKGNGTAQLDVVTSVTSDFGTFICEANNKRGRKLNN 333 Query: 4708 AKLKVTQP 4715 LK+ P Sbjct: 334 IMLKMAVP 341 Score = 37.9 bits (84), Expect = 0.20 Identities = 55/235 (23%), Positives = 82/235 (34%), Gaps = 23/235 (9%) Query: 342 NPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI-EISEKALAPQFVKVCQD 400 NP+ ++ G L +++ S V + + + E + ISE+A+ +K D Sbjct: 111 NPSKYVMNDGCLVIKNLQTSDVASYKCLAKNNIGEISAEVEVTRISEQAVITSDIK---D 167 Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460 G C TG V W N +G + I ++ LSD+ Sbjct: 168 ATKVVGDAFEVACEATGASPLSVEWKRNGSPYLGQEK------SNGKSVIKIQSLKLSDA 221 Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV--ERFST-LNVREGE--PVVLNARAV 515 TC A N K V AP V E T L+ G PV + + Sbjct: 222 AQFTCTASNGLQFNGKDVVSTKSFKLTVEAPPTVVLEGSKTPLHSFVGNTIPVTIKCQFT 281 Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 G P P + KDG + G + LD+ + SD + C A N G Sbjct: 282 GLPMPTVVMTKDGKEVAKG--------NGTAQLDVVTSVTSDFGTFICEANNKRG 328 Score = 36.7 bits (81), Expect = 0.46 Identities = 71/319 (22%), Positives = 127/319 (39%), Gaps = 31/319 (9%) Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774 F+ E G + ++W NG P+ + + G + I + DA ++TC A+N Sbjct: 176 FEVACEATGASPLSVEWKRNGSPYLGQEKSN-----GKSVIKIQSLKLSDAAQFTCTASN 230 Query: 3775 ------KWGSATTTAKITCSAKRDIVLE-SQLP-QGMSGEKIKELERGRISDAPKEEPIV 3826 K +T + K+T A +VLE S+ P G I + + + P ++ Sbjct: 231 GLQFNGKDVVSTKSFKLTVEAPPTVVLEGSKTPLHSFVGNTIPVTIKCQFTGLPMPTVVM 290 Query: 3827 STPPKFI------TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880 + K + Q+ T S+ F C K KL + +P G Sbjct: 291 TKDGKEVAKGNGTAQLDVVTSVTSDFGTFICEANNKRGRKLNNIMLK--MAVPPGKPLDV 348 Query: 3881 VYDMGFVSLDILYVY-AEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939 + ++ + + + A D G YI + G +ATI KK L+++ R K Sbjct: 349 KANKTCDTITLSWKHPASDGGMYIEDYIISVGSR-KEATIDDKK-QMFKLESKFQRNTKY 406 Query: 3940 SEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAP 3999 + ++ +Y+T D Y + PP+ +T Q++++ E T +E Sbjct: 407 NVSIQARNKAGPGERETLYITTDK-YCI--PSPPK-ITSKQTESNGPEYMVT-WEAPDFD 461 Query: 4000 VGDPNMK--VEWFFNGKPL 4016 DP++K VEW +P+ Sbjct: 462 GHDPDLKYRVEWTRTSEPV 480 Score = 36.7 bits (81), Expect = 0.46 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 11/88 (12%) Query: 929 FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988 FE E G S L VEW ++G P + + G + I+S+ + DA +TC A N Sbjct: 176 FEVACEATGASPLSVEWKRNGSPYLGQEK-----SNGKSVIKIQSLKLSDAAQFTCTASN 230 Query: 989 AI---GQ---ATTSANLTIVTKKDIIAE 1010 + G+ +T S LT+ ++ E Sbjct: 231 GLQFNGKDVVSTKSFKLTVEAPPTVVLE 258 Score = 36.7 bits (81), Expect = 0.46 Identities = 15/38 (39%), Positives = 23/38 (60%) Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202 G LD++ + D GT++C+A NK G +N LK+A Sbjct: 302 GTAQLDVVTSVTSDFGTFICEANNKRGRKLNNIMLKMA 339 Score = 35.5 bits (78), Expect = 1.1 Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%) Query: 1647 SGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN-QLEDTSKYQ------- 1698 +G Y CR ++ +A A + S Y+ ++G L N Q D + Y+ Sbjct: 88 AGKYECRG--SINKATVELEATCNPNPSKYV--MNDGCLVIKNLQTSDVASYKCLAKNNI 143 Query: 1699 -RHSAQDEV--ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755 SA+ EV I++ V T +KD A FE G L VEW RNG P Sbjct: 144 GEISAEVEVTRISEQAVITSDIKDATKVVGDA--FEVACEATGASPLSVEWKRNGSPYLG 201 Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINEL---GEAVTSSTLF 1801 + G + ++ + D+ +TC A N L G+ V S+ F Sbjct: 202 QEKSN-----GKSVIKIQSLKLSDAAQFTCTASNGLQFNGKDVVSTKSF 245 >SB_43033| Best HMM Match : I-set (HMM E-Value=3.3e-18) Length = 93 Score = 47.6 bits (108), Expect = 2e-04 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 3/91 (3%) Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682 P+I + V EG+ + SC G+P P+ QW+K D + S + L Sbjct: 3 PDISTHPSPQTVTEGENVTLSCVAEGRPTPSYQWFKDDSPFDAENNTRAS--LSQGNLIF 60 Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVA-AKLKV 4712 ++ +D G Y C+A NS VT + A+L V Sbjct: 61 TKISRDDHGQYYCLANNSVSNVTSSIAQLNV 91 Score = 44.0 bits (99), Expect = 0.003 Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 4/81 (4%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 VTEG+ C GRP P WF +D + N + +++ GN L+ T ++ D G Sbjct: 14 VTEGENVTLSCVAEGRPTPSYQWFKDDSPFDAENNTRASLSQ-GN--LIFTKISRDDHGQ 70 Query: 463 VTCVARNK-SGETAFQCRLNV 482 C+A N S T+ +LNV Sbjct: 71 YYCLANNSVSNVTSSIAQLNV 91 Score = 39.1 bits (87), Expect = 0.086 Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 3/82 (3%) Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557 S V EGE V L+ A G PTP W KD P R G L + D Sbjct: 10 SPQTVTEGENVTLSCVAEGRPTPSYQWFKDDSPFDAENNTRASLSQG--NLIFTKISRDD 67 Query: 558 AAWYQCTAQN-VAGSTATRARL 578 Y C A N V+ T++ A+L Sbjct: 68 HGQYYCLANNSVSNVTSSIAQL 89 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846 EG+N+ C E PT +WF ++ P + +++ S +L T +D G Y Sbjct: 16 EGENVTLSCVAEGR--PTPSYQWFKDDSPFDAENNTRAS--LSQGNLIFTKISRDDHGQY 71 Query: 2847 TCKATNSKGSATTS 2860 C A NS + T+S Sbjct: 72 YCLANNSVSNVTSS 85 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 5/88 (5%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701 P +TH S + EG++V L E R P+ +WFK+ +++ G Sbjct: 3 PDISTH-PSPQTVTEGENVTLSCVAEGRPTPSY--QWFKDDSPFDAENNTRASLSQG--N 57 Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVST 2729 L + DD G Y C A N + S+ Sbjct: 58 LIFTKISRDDHGQYYCLANNSVSNVTSS 85 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912 P ++EG++ C E P P+ +W+ + + + R S G L + + Sbjct: 11 PQTVTEGENVTLSCVAEGRPTPSY--QWFKDDSPFDAENNTRASLSQG--NLIFTKISRD 66 Query: 1913 DSGEYTCKAINNLGQAVSSI-RLNV 1936 D G+Y C A N++ SSI +LNV Sbjct: 67 DHGQYYCLANNSVSNVTSSIAQLNV 91 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 5/89 (5%) Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967 KP+ T Q ++ EG E G T +W KD P +A + + G + Sbjct: 2 KPDISTHPSPQ-TVTEGENVTLSCVAE--GRPTPSYQWFKDDSPFDAENNTRASLSQGNL 58 Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 T ++ D G Y C A N++ T+S Sbjct: 59 IFT--KISRDDHGQYYCLANNSVSNVTSS 85 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Query: 85 QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144 +G N G PTP W + +P N + R + G+ L+ +I D G+Y Sbjct: 16 EGENVTLSCVAEGRPTPSYQWFKDDSPFDAEN--NTRASLSQGN--LIFTKISRDDHGQY 71 Query: 145 TCTARNQYGEAICSV 159 C A N S+ Sbjct: 72 YCLANNSVSNVTSSI 86 >SB_15415| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1390 Score = 47.6 bits (108), Expect = 2e-04 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 5/74 (6%) Query: 4643 SCKIVGKPLPTVQWY-KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701 +C+ G P PT+ WY +G L +KY + + L+I ED G Y C A N+ Sbjct: 729 NCEAYGSPQPTMFWYSRGKDLTNRNKYTHFNNGS----LKIMNLEKEDTGKYMCTASNTL 784 Query: 4702 GRVTVAAKLKVTQP 4715 G+ TV +L+V P Sbjct: 785 GKQTVMRRLRVQIP 798 Score = 46.4 bits (105), Expect = 6e-04 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928 E Y P + WY GK L + ++Y N+ +L I+ + ED+G+Y C A N LG+ Sbjct: 731 EAYGSPQPTMFWYSRGKDLTNRNKYTHFNN---GSLKIMNLEKEDTGKYMCTASNTLGKQ 787 Query: 1929 VSSIRLNVQSKESIIRD 1945 RL VQ S +D Sbjct: 788 TVMRRLRVQIPPSPPQD 804 Score = 46.0 bits (104), Expect = 8e-04 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350 G+P+P + W+ G+ L N NK+ T N+ +L++ N +K D+G Y A N G Sbjct: 734 GSPQPTMFWYSRGKDLTNRNKY---THFNNGSLKIMNLEKEDTGKYMCTASNTLGKQTVM 790 Query: 351 GYLAVESP 358 L V+ P Sbjct: 791 RRLRVQIP 798 Score = 40.3 bits (90), Expect = 0.037 Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 13/132 (9%) Query: 737 TSQHPETLQY--IQQLEDYSKYQHQESIEEQTSQRPQ---FIRPLQD-LGELQEGRNAHF 790 T +TL Y ++ + E + ++T +R + F R L D L + + + Sbjct: 671 TDMESDTLYYFWVRAITAVGIGNASEVVSKRTMERIKASIFDRTLPDTLSKWKTFAILNC 730 Query: 791 EAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNK 850 EA +P PTM WY G+ +T ++ T FN G SL IM+L ED G Y A N Sbjct: 731 EAYGSP--QPTMF--WYSRGKDLTNRNKYTH-FNNG--SLKIMNLEKEDTGKYMCTASNT 783 Query: 851 LGEAISTASIRV 862 LG+ +RV Sbjct: 784 LGKQTVMRRLRV 795 Score = 39.9 bits (89), Expect = 0.049 Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 6/112 (5%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR-TADEY-- 4678 P I+ P D+ V + FSC +G + W+ G K + S Q+ R T D Sbjct: 2 PAVIVSPPSDRSVEVFGEMAFSCVAIGNLPIMLSWFNGSKQMVDSSRVQIMRYTKDNAHL 61 Query: 4679 ---TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727 TL +S+ D +Y C N GR K+ V + ++P ++ + Sbjct: 62 VNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQESPSNPSVPRVSDI 113 Score = 39.9 bits (89), Expect = 0.049 Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 3/68 (4%) Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193 E P T+ W+ G+ + ++Y TH F +L I+ ED+G YMC A+N LG+ Sbjct: 731 EAYGSPQPTMFWYSRGKDLTNRNKY--TH-FNNGSLKIMNLEKEDTGKYMCTASNTLGKQ 787 Query: 2194 VNTCTLKV 2201 L+V Sbjct: 788 TVMRRLRV 795 Score = 39.1 bits (87), Expect = 0.086 Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 3/55 (5%) Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055 G P + W+ GK L ++N++T + MN + ED+G+Y+C A+N G Sbjct: 734 GSPQPTMFWYSRGKDLTNRNKYTHFNNGSLKIMN---LEKEDTGKYMCTASNTLG 785 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 3/69 (4%) Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855 N E P + W+ K L + +Y TH F+ SL I + +ED+G Y C A+N+ G Sbjct: 729 NCEAYGSPQPTMFWYSRGKDLTNRNKY--TH-FNNGSLKIMNLEKEDTGKYMCTASNTLG 785 Query: 2856 SATTSGSLR 2864 T LR Sbjct: 786 KQTVMRRLR 794 Score = 38.3 bits (85), Expect = 0.15 Identities = 17/62 (27%), Positives = 36/62 (58%), Gaps = 3/62 (4%) Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371 P + W+ GK L + ++Y F++ + I+++ +E++G+Y C A+N LG+ + Sbjct: 736 PQPTMFWYSRGKDLTNRNKYTHFNNGSLKIMNL---EKEDTGKYMCTASNTLGKQTVMRR 792 Query: 3372 LK 3373 L+ Sbjct: 793 LR 794 Score = 38.3 bits (85), Expect = 0.15 Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 3/48 (6%) Query: 1613 WYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660 WY K L + +++T NN +L IM+ ED+G Y C A N LG+ Sbjct: 742 WYSRGKDLTNRNKYTHFNNG---SLKIMNLEKEDTGKYMCTASNTLGK 786 Score = 37.9 bits (84), Expect = 0.20 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 9/107 (8%) Query: 1030 SKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSA 1089 SKRT E +K + R L K + EA PQ T+ WY GK +T+ Sbjct: 699 SKRTMERIKASIFDRTLPDTLSKWKTFA--ILNCEAYGSPQP----TMFWYSRGKDLTNR 752 Query: 1090 NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 N+ Y F +L I ++ ED+G Y A N G+ + + V+ Sbjct: 753 NK---YTHFNNGSLKIMNLEKEDTGKYMCTASNTLGKQTVMRRLRVQ 796 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%) Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568 +LN A G+P P + W G + N H + G +L I + D Y CTA N Sbjct: 727 ILNCEAYGSPQPTMFWYSRGKD-LTNRNKYTHFNNG--SLKIMNLEKEDTGKYMCTASNT 783 Query: 569 AGSTATRARL 578 G RL Sbjct: 784 LGKQTVMRRL 793 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 5/95 (5%) Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367 ++A F R L + + T L C + G + W+ GK + +++ F+ Sbjct: 706 IKASIFDRTLPDTLSKWKTFAILNC--EAYGSPQPTMFWYSRGKDLTNRNKYT---HFNN 760 Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 +L ++++ ED+G Y C A+N LG+ LRV Sbjct: 761 GSLKIMNLEKEDTGKYMCTASNTLGKQTVMRRLRV 795 Score = 37.1 bits (82), Expect = 0.35 Identities = 20/54 (37%), Positives = 33/54 (61%), Gaps = 3/54 (5%) Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912 P+ + WY GK L + ++Y T ++ G SL I+ + ED+G+Y+C A N G+ Sbjct: 736 PQPTMFWYSRGKDLTNRNKY-THFNNG--SLKIMNLEKEDTGKYMCTASNTLGK 786 Score = 37.1 bits (82), Expect = 0.35 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 5/63 (7%) Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066 PTM WY G+ + +++ T ++ G +L I+ EDTG YMC A+N +G+ Sbjct: 738 PTMF--WYSRGKDLTNRNKY-THFNNG--SLKIMNLEKEDTGKYMCTASNTLGKQTVMRR 792 Query: 2067 VKV 2069 ++V Sbjct: 793 LRV 795 Score = 35.9 bits (79), Expect = 0.80 Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509 P + WY GK L +++ F + I+ + ED+G+Y+C A N G+ Sbjct: 736 PQPTMFWYSRGKDLTNRNKYTHFNNGSLKIMNLEK---EDTGKYMCTASNTLGKQTVMRR 792 Query: 3510 MKVQ 3513 ++VQ Sbjct: 793 LRVQ 796 Score = 35.5 bits (78), Expect = 1.1 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459 G P + W+ K + + ++ T F S+ I ++ ED G YMC ASN LG+ Sbjct: 734 GSPQPTMFWYSRGKDLTNRNKYTH---FNNGSLKIMNLEKEDTGKYMCTASNTLGK 786 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 412 DCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469 +C G P P + W+ + + R+ Y H N +L I N+ D+G C A N Sbjct: 729 NCEAYGSPQPTMFWYSRGKDLTNRNKYTH------FNNGSLKIMNLEKEDTGKYMCTASN 782 Query: 470 KSGETAFQCRLNV 482 G+ RL V Sbjct: 783 TLGKQTVMRRLRV 795 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 5/58 (8%) Query: 97 GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154 G+P P + W + L NKY+ +N SL I + D G+Y CTA N G+ Sbjct: 734 GSPQPTMFWYSRGKDLTNRNKYT-HFNNG----SLKIMNLEKEDTGKYMCTASNTLGK 786 Score = 33.9 bits (74), Expect = 3.2 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 3/64 (4%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P + W+ G LT R K T F +L I +L +D+G Y C A+N LG+ Sbjct: 736 PQPTMFWYSRGKDLTN--RNKYTH-FNNGSLKIMNLEKEDTGKYMCTASNTLGKQTVMRR 792 Query: 2732 IKIE 2735 ++++ Sbjct: 793 LRVQ 796 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P+ + W G + N+ T ++ +N++ ED+G Y C A N LG+ Sbjct: 734 GSPQPTMFWYSRGKDLTNRNKYTHFNNGSLKIMNLE---KEDTGKYMCTASNTLGKQTVM 790 Query: 1798 STLFVQ 1803 L VQ Sbjct: 791 RRLRVQ 796 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 8/82 (9%) Query: 3711 GPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV----HTLNDFGFI--ALDIDYIYARD 3764 G + F C +G+ + + WF+ + SRV +T ++ + L + + D Sbjct: 18 GEMAFSCVA--IGNLPIMLSWFNGSKQMVDSSRVQIMRYTKDNAHLVNGTLHVSDLRLWD 75 Query: 3765 AGEYTCRATNKWGSATTTAKIT 3786 EY+CR N++G T KIT Sbjct: 76 TKEYSCRVGNQFGRDEKTFKIT 97 Score = 33.1 bits (72), Expect = 5.7 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 3/58 (5%) Query: 3593 WFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 W+ GK L ++ N+ L+I + + D G Y C A+N G+ TV +L+V+ Sbjct: 742 WYSRGKDLTNRNKYTHFNNGS---LKIMNLEKEDTGKYMCTASNTLGKQTVMRRLRVQ 796 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 3/55 (5%) Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534 W+ G+ +T +R + H F +L I++L ED+G Y C A N +G V RL Sbjct: 742 WYSRGKDLT--NRNKYTH-FNNGSLKIMNLEKEDTGKYMCTASNTLGKQTVMRRL 793 Score = 32.7 bits (71), Expect = 7.5 Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 3/58 (5%) Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718 E G P + W G+ + +++T F SL +++L +D+G+Y C A + G Sbjct: 731 EAYGSPQPTMFWYSRGKDLTNRNKYT---HFNNGSLKIMNLEKEDTGKYMCTASNTLG 785 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590 G P WY G +L +R + TH F +L I ++ D G YMC A N G Sbjct: 734 GSPQPTMFWYSRGKDLT--NRNKYTH-FNNGSLKIMNLEKEDTGKYMCTASNTLG 785 >SB_42486| Best HMM Match : Pkinase_Tyr (HMM E-Value=0) Length = 1554 Score = 47.6 bits (108), Expect = 2e-04 Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 44/291 (15%) Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP-AT 4608 N K +QP K+++ D YT+L AY QD+G+Y+C A N D E + + P A Sbjct: 71 NEKPLQP---GKVIKTDDVYTILNF-AY-QDAGQYQCKATN------LDGETIFTDPNAC 119 Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK----GDKLIK 4664 K +P P ++PL +++G + F+C T++W K G + Sbjct: 120 KVFGRPNV----IPDVTVDPLYAVQLSQGDSFNFTCS--SATHTTLKWTKRPKTGSESDV 173 Query: 4665 PSKYFQM----SRTADEYTLRISEAFPEDEGDYKCV-AYNSAGRVTVAAKLKVTQPDQAD 4719 PS + S+ L I A P D YKC+ YN +A+ L V + ++ Sbjct: 174 PSSQTVLIKDTSKNQQRLILMIRNAQPSDTATYKCILTYNGQEHYKLAS-LIVYKNEKPV 232 Query: 4720 NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP----------ETPDF-- 4767 + + + E + +P W ++G I ET + Sbjct: 233 ITSHSSTTGPVTMQEPSDVEIFCSFQGYPQPKNTWSKDGTEITFGGCIAGQPCETKKYIL 292 Query: 4768 ----QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 ++ E + + + G Y +D G +TC A + G + L V+ T Sbjct: 293 KTKRKLSTEYISHLTIKGARYPDDHGIYTCSAANSLGVAKADITLNVEVPT 343 Score = 45.6 bits (103), Expect = 0.001 Identities = 48/212 (22%), Positives = 81/212 (38%), Gaps = 29/212 (13%) Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGK--MTRFDCRVTGRPYPEVTWFIND----- 429 R + I++ A+ P + D+ V + K + +C+V+G P P V W+ + Sbjct: 482 RIVNDSIKVEVLAVTPPIISEMPDQTVKKEKTDIVEVNCKVSGYPKPTVIWYKHSPGETE 541 Query: 430 ----RQIRDDYNHKILVNESGNHALMITNVTLS----------DSGVVTCVARNKSGETA 475 QI D + + ++ SG C+A N+ GE Sbjct: 542 WRRLSQIPDLVRSNGCTQSRSGYYFYLDSIGSPLVICQPRHELHSGKYKCIATNELGEDQ 601 Query: 476 FQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP 535 LNV E +++ PK L+V + +A G P P + W + + Sbjct: 602 RIASLNVEEGARILKPK----SKLLSVALDTNFNQSCQASGNPVPTVQWMRHE----KSG 653 Query: 536 ELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 + + T G++ L IP+ D Y CTA N Sbjct: 654 DKLLSTGLGSALLVIPKVMTKDLTNYTCTAAN 685 Score = 41.9 bits (94), Expect = 0.012 Identities = 46/210 (21%), Positives = 80/210 (38%), Gaps = 22/210 (10%) Query: 263 VSPPKIAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321 V+PP I++ P + +E D + ++SG P+P V W+K+ + I Sbjct: 495 VTPPIISEMPDQTVKKEKTDIVEVNCKVSGYPKPTVIWYKHSPGETEWRRLSQIP----D 550 Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381 +R +S SG+Y L + ++ + S + QR Sbjct: 551 LVRSNGCTQSRSGYYFYLDSIGSPLVICQPRHELHSGKYKCIATNE----LGEDQRIASL 606 Query: 382 RIEISEKALAP--QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439 +E + L P + + V D + + C+ +G P P V W +++ K Sbjct: 607 NVEEGARILKPKSKLLSVALDTNFNQ------SCQASGNPVPTVQWMRHEKS-----GDK 655 Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARN 469 +L G+ L+I V D TC A N Sbjct: 656 LLSTGLGSALLVIPKVMTKDLTNYTCTAAN 685 Score = 39.5 bits (88), Expect = 0.065 Identities = 56/230 (24%), Positives = 88/230 (38%), Gaps = 32/230 (13%) Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA--IEFSCKI 4646 +N +G CDA + + + P II + D+ V + + +E +CK+ Sbjct: 463 VNDSGVYSCDALALRPQLNRIVNDSIKVEVLAVTPPIISEMPDQTVKKEKTDIVEVNCKV 522 Query: 4647 VGKPLPTVQWYK---GD----------KLIKPSKYFQMSRTADEYTLRISEAF----PED 4689 G P PTV WYK G+ L++ + Q Y I P Sbjct: 523 SGYPKPTVIWYKHSPGETEWRRLSQIPDLVRSNGCTQSRSGYYFYLDSIGSPLVICQPRH 582 Query: 4690 E---GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746 E G YKC+A N G A L V + A L + L + + Q + Sbjct: 583 ELHSGKYKCIATNELGEDQRIASLNV--EEGARILKPKSKLLSVAL--DTNFNQSCQASG 638 Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEG-NNAVLLIGNTYEEDTGTFTCRA 4795 PT+QW+R E +++ G +A+L+I +D +TC A Sbjct: 639 NPVPTVQWMRH-----EKSGDKLLSTGLGSALLVIPKVMTKDLTNYTCTA 683 Score = 38.7 bits (86), Expect = 0.11 Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 19/137 (13%) Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622 L+ G+ ++ + SGKY+C+A N GE + A V A KPK + + Sbjct: 568 LDSIGSPLVICQPRHELHSGKYKCIATNELGEDQRIASLNVEEGARILKPKSKLLS---- 623 Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682 VA SC+ G P+PTVQW + +K S +S L I Sbjct: 624 -----------VALDTNFNQSCQASGNPVPTVQWMRHEK----SGDKLLSTGLGSALLVI 668 Query: 4683 SEAFPEDEGDYKCVAYN 4699 + +D +Y C A N Sbjct: 669 PKVMTKDLTNYTCTAAN 685 Score = 36.7 bits (81), Expect = 0.46 Identities = 21/49 (42%), Positives = 26/49 (53%), Gaps = 5/49 (10%) Query: 2016 NGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064 N +P+Q G KT D Y L+ Y +D G Y CKATN GE + T Sbjct: 71 NEKPLQPGKVIKT--DDVYTILNFAY---QDAGQYQCKATNLDGETIFT 114 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/82 (28%), Positives = 32/82 (39%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 LMI N SD+ C+ E L V + E+ V + ++E V Sbjct: 193 LMIRNAQPSDTATYKCILTYNGQEHYKLASLIVYKNEKPVITSHSSTTGPVTMQEPSDVE 252 Query: 510 LNARAVGTPTPRITWQKDGVPI 531 + G P P+ TW KDG I Sbjct: 253 IFCSFQGYPQPKNTWSKDGTEI 274 Score = 36.7 bits (81), Expect = 0.46 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Query: 4095 QVTPEQVVEESKARCPPVFVSLPD-AVTVEEGEWARFCCRVTGHPKPRVMW 4144 ++ + + E A PP+ +PD V E+ + C+V+G+PKP V+W Sbjct: 482 RIVNDSIKVEVLAVTPPIISEMPDQTVKKEKTDIVEVNCKVSGYPKPTVIW 532 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/64 (43%), Positives = 33/64 (51%), Gaps = 7/64 (10%) Query: 3595 HNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA--TVSCKLQVKGR 3652 +N KPL G +KT D + IL YQ DAG Y CKATN GE T +V GR Sbjct: 70 YNEKPLQPGKVIKT--DDVYTILNFA--YQ-DAGQYQCKATNLDGETIFTDPNACKVFGR 124 Query: 3653 QGII 3656 +I Sbjct: 125 PNVI 128 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 7/80 (8%) Query: 2137 NDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA----EDSGTYMCKATNKLGE 2192 ND + T + QK G+ + + D +YT +D+G Y CKATN GE Sbjct: 52 NDENATTTLLYR-QKFMGGYNEKPLQPGKVIKTDDVYTILNFAYQDAGQYQCKATNLDGE 110 Query: 2193 AVNT--CTLKVAGHRNIILD 2210 + T KV G N+I D Sbjct: 111 TIFTDPNACKVFGRPNVIPD 130 Score = 35.9 bits (79), Expect = 0.80 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 18/102 (17%) Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG----------HRY--RTSNDF 1899 GP + E C + YP P + W +G + G +Y +T Sbjct: 241 GPVTMQEPSDVEIFCSFQGYPQP--KNTWSKDGTEITFGGCIAGQPCETKKYILKTKRKL 298 Query: 1900 GFAALDILTV----YGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937 + LT+ Y +D G YTC A N+LG A + I LNV+ Sbjct: 299 STEYISHLTIKGARYPDDHGIYTCSAANSLGVAKADITLNVE 340 Score = 35.5 bits (78), Expect = 1.1 Identities = 14/27 (51%), Positives = 16/27 (59%) Query: 1376 YPEDSGVYTCQATNQLGEAVTSCALRV 1402 YP+D G+YTC A N LG A L V Sbjct: 313 YPDDHGIYTCSAANSLGVAKADITLNV 339 Score = 33.9 bits (74), Expect = 3.2 Identities = 39/166 (23%), Positives = 68/166 (40%), Gaps = 14/166 (8%) Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714 Q + G KP + ++ +T D YT+ ++ A+ +D G Y+C A N G Sbjct: 64 QKFMGGYNEKPLQPGKVIKTDDVYTI-LNFAY-QDAGQYQCKATNLDGETIFTDPNACKV 121 Query: 4715 PDQADNLPALT--PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMI 4770 + + +P +T PL + + +G F +S T++W + E+ P Q + Sbjct: 122 FGRPNVIPDVTVDPLYAVQLSQGD--SFNFTCSSATHTTLKWTKRPKTGSESDVPSSQTV 179 Query: 4771 ------HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 +L+I N DT T+ C T + A L+V Sbjct: 180 LIKDTSKNQQRLILMIRNAQPSDTATYKCILTYNGQEHYKLASLIV 225 Score = 33.5 bits (73), Expect = 4.3 Identities = 13/25 (52%), Positives = 20/25 (80%) Query: 3348 YEENSGEYECVATNKLGRDSTKANL 3372 +E +SG+Y+C+ATN+LG D A+L Sbjct: 582 HELHSGKYKCIATNELGEDQRIASL 606 Score = 32.3 bits (70), Expect = 9.9 Identities = 13/26 (50%), Positives = 17/26 (65%) Query: 2710 DDSGIYTCKATNLLGEAVSTASIKIE 2735 DD GIYTC A N LG A + ++ +E Sbjct: 315 DDHGIYTCSAANSLGVAKADITLNVE 340 >SB_12208| Best HMM Match : ig (HMM E-Value=6.9e-30) Length = 474 Score = 47.6 bits (108), Expect = 2e-04 Identities = 54/201 (26%), Positives = 79/201 (39%), Gaps = 19/201 (9%) Query: 666 PTMKIEWLKNGQSIEASSRFTSIF--RFGYISLDMLSLNIQ--DSGEYTCRAVSATGVAE 721 P K W KNG + S+ + + GY D++ N+Q D G Y+C A+ E Sbjct: 37 PAEKFIWRKNGHLLSNSTIVYPSYTPQLGYWE-DLVISNVQLKDEGSYSCTAIQGNSQDE 95 Query: 722 TKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGE 781 ++V T L + L + E+IEE + P E Sbjct: 96 DWYTVNVYGNG--HNTETLKNILGHSHALTGHFLII-LENIEEHVTPPPA---TALFYVE 149 Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841 L G A + P +R WYK+G P++ S+I VSL+I R D G Sbjct: 150 LSRGDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQSDQG 201 Query: 842 SYTVRAVNKLGEAISTASIRV 862 Y RA N +G I I++ Sbjct: 202 MYYCRANNTVGSEIRPILIKM 222 Score = 45.6 bits (103), Expect = 0.001 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 6/86 (6%) Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545 E+ V P + + G+ V+ +A G P P + W K+G+P+ P+ ++ Sbjct: 134 EEHVTPPPATALFYVELSRGDRAVVRCKADGWPPPYLRWYKEGMPLSPHSKIE------E 187 Query: 546 STLDIPRAKASDAAWYQCTAQNVAGS 571 +L I A+ SD Y C A N GS Sbjct: 188 VSLHITFARQSDQGMYYCRANNTVGS 213 Score = 39.1 bits (87), Expect = 0.086 Identities = 52/216 (24%), Positives = 84/216 (38%), Gaps = 16/216 (7%) Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY--DFGYVA-LDILYAYAE 2045 V G+ + L ++ +N P + W NG + +Y GY L I + Sbjct: 20 VWPGNNITLNCSVI-LNGPAEKFIWRKNGHLLSNSTIVYPSYTPQLGYWEDLVISNVQLK 78 Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQP 2105 D G+Y C A + +V V +G +TL + L L + +E + Sbjct: 79 DEGSYSCTAIQGNSQDEDWYTVNVYG-NGHNTETL-KNILGHSHALTGHFLII-LENIEE 135 Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165 P TAL +E L GDRA C+ + P+L W+ G + + Sbjct: 136 HVTPPPATALFYVE-LSRGDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE----- 187 Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 V+L I + D G Y C+A N +G + +K+ Sbjct: 188 -VSLHITFARQSDQGMYYCRANNTVGSEIRPILIKM 222 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 4/90 (4%) Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI--KTVSDFGFVV-LDIAYTQ 3215 +G+ G + C+V+ ++ P K W NG + +ST + G+ L I+ Q Sbjct: 18 QGVWPGNNITLNCSVI-LNGPAEKFIWRKNGHLLSNSTIVYPSYTPQLGYWEDLVISNVQ 76 Query: 3216 NHDSGEYVCRAYNKYGEDFTRATINCYGKG 3245 D G Y C A +D T+N YG G Sbjct: 77 LKDEGSYSCTAIQGNSQDEDWYTVNVYGNG 106 Score = 38.7 bits (86), Expect = 0.11 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 8/85 (9%) Query: 2651 YDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRND 2710 Y +L G + + + P L+ W+K G+ L+ ++++ V+L I R Sbjct: 147 YVELSRGDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQS 198 Query: 2711 DSGIYTCKATNLLGEAVSTASIKIE 2735 D G+Y C+A N +G + IK++ Sbjct: 199 DQGMYYCRANNTVGSEIRPILIKMK 223 Score = 38.3 bits (85), Expect = 0.15 Identities = 44/177 (24%), Positives = 71/177 (40%), Gaps = 21/177 (11%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 ++ G CK G P P ++WYK + P +E +L I+ A D+G Y Sbjct: 150 LSRGDRAVVRCKADGWPPPYLRWYKEGMPLSPHS------KIEEVSLHITFARQSDQGMY 203 Query: 4694 KCVAYNSAGRV--TVAAKLK-VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750 C A N+ G + K+K VT +A + T L V + + Sbjct: 204 YCRANNTVGSEIRPILIKMKQVTPRVKAKDHYVATRLGSTVSISCTASNVNLEF-----D 258 Query: 4751 TIQWLREG--ALIPETPDFQ----MIHEGN-NAVLLIGNTYEEDTGTFTCRATTAAG 4800 T +W R G A + ++ F +EG+ + L+I +D G + C T+ G Sbjct: 259 TTKWTRNGTEASVQQSQRFHTRDLYSYEGSMESTLIIKGVRIQDFGCYKCTVATSNG 315 Score = 36.7 bits (81), Expect = 0.46 Identities = 48/190 (25%), Positives = 72/190 (37%), Gaps = 18/190 (9%) Query: 1477 KVEWFKNGQPVTIGHRFRPIH--DFGYVA-LDIIDLIAEDSGIYTCRAVNLVGTDEVSCR 1533 K W KNG ++ P + GY L I ++ +D G Y+C A+ DE Sbjct: 40 KFIWRKNGHLLSNSTIVYPSYTPQLGYWEDLVISNVQLKDEGSYSCTAIQGNSQDEDWY- 98 Query: 1534 LTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEG 1592 T ++ + N L+ I H +++ + P T+L VE+ G Sbjct: 99 -----TVNVYGNGHNTETLKNILGHSHALTGHFLIILENIEEHVTPPPATALFYVELSRG 153 Query: 1593 QRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTC 1652 RA + L+ WY PL S+ E V+L I D G Y C Sbjct: 154 DRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQSDQGMYYC 205 Query: 1653 RAINALGEAV 1662 RA N +G + Sbjct: 206 RANNTVGSEI 215 Score = 36.3 bits (80), Expect = 0.61 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 6/55 (10%) Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233 P + WY G P+ ++I+ VS L I + + D G Y CRA N G + Sbjct: 166 PPPYLRWYKEGMPLSPHSKIEEVS------LHITFARQSDQGMYYCRANNTVGSE 214 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 8/94 (8%) Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914 +LS G A C+ + +P P +R WY G L + +L I D Sbjct: 149 ELSRGDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQSDQ 200 Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948 G Y C+A N +G + I + ++ ++ H Sbjct: 201 GMYYCRANNTVGSEIRPILIKMKQVTPRVKAKDH 234 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 6/84 (7%) Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900 VE S G R R + P + WY+ G L + V SL I + D G Sbjct: 148 VELSRGDRAVVRCKADGWPPPYLRWYKEGMPLSPHSKIEEV------SLHITFARQSDQG 201 Query: 3901 EYICRAVNDFGEDFTKATISCKKL 3924 Y CRA N G + I K++ Sbjct: 202 MYYCRANNTVGSEIRPILIKMKQV 225 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 8/69 (11%) Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847 GD C + P L+ W+ PL ++ + VSL IT + D G+Y Sbjct: 153 GDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQSDQGMYY 204 Query: 2848 CKATNSKGS 2856 C+A N+ GS Sbjct: 205 CRANNTVGS 213 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/102 (21%), Positives = 42/102 (41%), Gaps = 8/102 (7%) Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360 + E+I P + AL +E G + C+ G + W+ G P+ Sbjct: 129 ILENIEEHVTPPPATALFYVELSRGDRAVVRCKAD--GWPPPYLRWYKEGMPLS------ 180 Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 P + + V+L + D G+Y C+A N +G + +++ Sbjct: 181 PHSKIEEVSLHITFARQSDQGMYYCRANNTVGSEIRPILIKM 222 Score = 33.1 bits (72), Expect = 5.7 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 6/55 (10%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 G P + W++ + S+I + VS+ I+ R D+G+Y CRA+N +G Sbjct: 164 GWPPPYLRWYKEGMPLSPHSKIEE------VSLHITFARQSDQGMYYCRANNTVG 212 Score = 32.7 bits (71), Expect = 7.5 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 4/66 (6%) Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI--TKTHDFGY-VSMTISHVRDEDEG 2447 G +C +I G P K W +N L+ +S+ + + T GY + IS+V+ +DEG Sbjct: 23 GNNITLNCSVILNG-PAEKFIWRKNGHLLSNSTIVYPSYTPQLGYWEDLVISNVQLKDEG 81 Query: 2448 VYMCRA 2453 Y C A Sbjct: 82 SYSCTA 87 Score = 32.3 bits (70), Expect = 9.9 Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 9/93 (9%) Query: 70 SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 +PP +F ++G A K G P P + W ++ PL +K +V Sbjct: 138 TPPPATALFY-VELSRGDRAVVRCKADGWPPPYLRWYKEGMPLSPHSKIE--------EV 188 Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162 SL I D+G Y C A N G I + I+ Sbjct: 189 SLHITFARQSDQGMYYCRANNTVGSEIRPILIK 221 >SB_5499| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 183 Score = 47.2 bits (107), Expect = 3e-04 Identities = 25/66 (37%), Positives = 37/66 (56%), Gaps = 4/66 (6%) Query: 281 ADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339 A A+ V + NP+P+VTWFKNG R+ ++ K++ + TL + D+G YT Sbjct: 109 ASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSA---DTLEIAGLVPQDTGIYTCR 165 Query: 340 AENPNG 345 AEN G Sbjct: 166 AENARG 171 Score = 44.4 bits (100), Expect = 0.002 Identities = 43/190 (22%), Positives = 66/190 (34%), Gaps = 9/190 (4%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 PP I+ D++ Q I F C G P P V W +P+ L Sbjct: 2 PPRIVSEPTDQVATIHQNITFVCDTQGVPKPRVSWQNSQG--RPADRDPRITVLQSGALH 59 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741 I P ++ +N + +L + D L + A+ Sbjct: 60 IRGGVPTPRVTWQ---HNGRNLQYMTPRLVIRDARPQD--AGLYRCTGTNLAGRASAETS 114 Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 + S KP + W + G +P D + + L I +DTG +TCRA A G Sbjct: 115 VTVRSNPKPKVTWFKNGYRVPL--DDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARGH 172 Query: 4802 VETSAKLVVK 4811 + LVV+ Sbjct: 173 DTWNITLVVQ 182 Score = 43.2 bits (97), Expect = 0.005 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 4/66 (6%) Query: 2794 ECNVEPSRDPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852 E +V +P K+ WF N +P +YK T S +L+I +D+GIYTC+A N Sbjct: 112 ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAEN 168 Query: 2853 SKGSAT 2858 ++G T Sbjct: 169 ARGHDT 174 Score = 42.7 bits (96), Expect = 0.007 Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTG-ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721 E V R++P K+ WFKNG + + K T TL I L D+GIYTC+A N Sbjct: 112 ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAEN 168 Query: 2722 LLG 2724 G Sbjct: 169 ARG 171 Score = 41.9 bits (94), Expect = 0.012 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 4/63 (6%) Query: 2932 EGQVEPKNDPDLKIEWYFNG-KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYN 2990 E V +++P K+ W+ NG +V ++K TS TL++ + +D+GIYTC+A N Sbjct: 112 ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTCRAEN 168 Query: 2991 KRG 2993 RG Sbjct: 169 ARG 171 Score = 41.1 bits (92), Expect = 0.021 Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 6/67 (8%) Query: 1739 DPKLRVEWLRNG--VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796 +PK +V W +NG VP++ T D L + + P+D+G YTCRA N G Sbjct: 120 NPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTW 175 Query: 1797 SSTLFVQ 1803 + TL VQ Sbjct: 176 NITLVVQ 182 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/57 (43%), Positives = 30/57 (52%), Gaps = 12/57 (21%) Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYV-----ALDIIDLIAEDSGIYTCRAVNLVGTD 1528 KV WFKNG V P+ D Y L+I L+ +D+GIYTCRA N G D Sbjct: 124 KVTWFKNGYRV-------PLDDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARGHD 173 Score = 38.3 bits (85), Expect = 0.15 Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 12/180 (6%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P+ V D+ T + F C G P P V+W N + D + +I V +SG AL Sbjct: 3 PRIVSEPTDQVATIHQNITFVCDTQGVPKPRVSWQ-NSQGRPADRDPRITVLQSG--ALH 59 Query: 452 ITNVTLSDSGVVTC-VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 I GV T V +G ++ ++ + R + N+ Sbjct: 60 IRG------GVPTPRVTWQHNGRNLQYMTPRLVIRDARPQDAGLYRCTGTNLAGRASAET 113 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 + P P++TW K+G + P +++ + A TL+I D Y C A+N G Sbjct: 114 SVTVRSNPKPKVTWFKNGYRV-PLDDIK-YKQTSADTLEIAGLVPQDTGIYTCRAENARG 171 Score = 37.5 bits (83), Expect = 0.26 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 652 GKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTC 711 G+ ET + +P K+ W KNG + + +L++ L QD+G YTC Sbjct: 107 GRASAETSVTVRSNPKPKVTWFKNGYRVPLDD--IKYKQTSADTLEIAGLVPQDTGIYTC 164 Query: 712 RAVSATG 718 RA +A G Sbjct: 165 RAENARG 171 Score = 37.1 bits (82), Expect = 0.35 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 4/71 (5%) Query: 3850 ECRVEPKEDPKLRIEWYRNGKLLPSGH-RYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908 E V + +PK ++ W++NG +P +Y+ +L+I + +D+G Y CRA N Sbjct: 112 ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAEN 168 Query: 3909 DFGEDFTKATI 3919 G D T+ Sbjct: 169 ARGHDTWNITL 179 Score = 37.1 bits (82), Expect = 0.35 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 6/63 (9%) Query: 3590 RVEWFHNGK--PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647 +V WF NG PL +T D LEI G+ +D G+YTC+A N G T + L Sbjct: 124 KVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTWNITL 179 Query: 3648 QVK 3650 V+ Sbjct: 180 VVQ 182 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 5/69 (7%) Query: 415 VTGRPYPEVTWFINDRQIR-DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473 V P P+VTWF N ++ DD +K ++ L I + D+G+ TC A N G Sbjct: 117 VRSNPKPKVTWFKNGYRVPLDDIKYK----QTSADTLEIAGLVPQDTGIYTCRAENARGH 172 Query: 474 TAFQCRLNV 482 + L V Sbjct: 173 DTWNITLVV 181 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 6/78 (7%) Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFR-TFCDFGFVILEISPTYPEDSGEYLC 3495 A E +T +P KV W+ NG + +++ T D LEI+ P+D+G Y C Sbjct: 109 ASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTC 164 Query: 3496 RAYNNYGEAVTTASMKVQ 3513 RA N G ++ VQ Sbjct: 165 RAENARGHDTWNITLVVQ 182 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYR-TSNDFGFAALDILTVYG 1911 T L+ SA + P P +V W+ NG +V +Y+ TS D L+I + Sbjct: 103 TNLAGRASAETSVTVRSNPKP--KVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVP 156 Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ 1937 +D+G YTC+A N G +I L VQ Sbjct: 157 QDTGIYTCRAENARGHDTWNITLVVQ 182 Score = 34.7 bits (76), Expect = 1.9 Identities = 48/181 (26%), Positives = 66/181 (36%), Gaps = 18/181 (9%) Query: 4425 HEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483 H+ F + G P P + W + P P T L IR + Sbjct: 17 HQNITFVCDTQGVPKPRVSWQNSQGRPADRDPRI---TVLQSGALHIRGGVPTPRVTWQ- 72 Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543 N + LV+ + R Q G+ + T A + + VR + KP Sbjct: 73 --HNGRNLQYMTPRLVIRDARPQD-AGLYRCTGTNLAGRASAETSVTVR-----SNPKP- 123 Query: 4544 DVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602 V W KNG +V DI+ K D TL I PQD+G Y C A N+ G + V Sbjct: 124 KVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTCRAENARGHDTWNITLV 180 Query: 4603 V 4603 V Sbjct: 181 V 181 Score = 34.7 bits (76), Expect = 1.9 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 3/95 (3%) Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101 +P+ G + T + G+ A E V +S+ V W+ NG ++ + I+ Y Sbjct: 91 RPQDAGLYRCTGTNLAGR-ASAETSVTVRSNPKPKVTWFKNGYRVP-LDDIK-YKQTSAD 147 Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136 L+IA + +D+G+YT A NA G + ++ V+ Sbjct: 148 TLEIAGLVPQDTGIYTCRAENARGHDTWNITLVVQ 182 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 1594 RAHFERRLIPVSDATLKVEWYHNNKPLKSGS-RFTETNNFGFVALDIMSCLPEDSGTYTC 1652 RA E + S+ KV W+ N + ++ +T+ L+I +P+D+G YTC Sbjct: 108 RASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTC 164 Query: 1653 RAINALG 1659 RA NA G Sbjct: 165 RAENARG 171 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 6/75 (8%) Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224 A E +V +P K+ W+ NG P+ +T +D L+IA D+G Y C Sbjct: 109 ASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTC 164 Query: 3225 RAYNKYGEDFTRATI 3239 RA N G D T+ Sbjct: 165 RAENARGHDTWNITL 179 Score = 34.3 bits (75), Expect = 2.5 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 5/48 (10%) Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615 T L+I +A PQD+G Y C N AG A + V + PKP+ Sbjct: 82 TPRLVIRDARPQDAGLYRCTGTNLAGRASAETSVTV-----RSNPKPK 124 Score = 33.9 bits (74), Expect = 3.2 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 19/110 (17%) Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND---------PTMRVEWYCNGRP 2019 Q+ +FV + KP + + ++G P + +T + PT RV W NGR Sbjct: 18 QNITFVCDTQGVPKPRVSWQNSQGRPADRDPRITVLQSGALHIRGGVPTPRVTWQHNGRN 77 Query: 2020 VQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069 +Q + T L I A +D G Y C TN G A +SV V Sbjct: 78 LQ----YMTP------RLVIRDARPQDAGLYRCTGTNLAGRASAETSVTV 117 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 4/77 (5%) Query: 2126 RAHFECRVEPINDPHLTIDWFHNGQKIRAGH-RYRTTHDFGYVALDILYTYAEDSGTYMC 2184 RA E V ++P + WF NG ++ +Y+ T L+I +D+G Y C Sbjct: 108 RASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTC 164 Query: 2185 KATNKLGEAVNTCTLKV 2201 +A N G TL V Sbjct: 165 RAENARGHDTWNITLVV 181 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 8/61 (13%) Query: 95 LRGNPTPVVSWTRK--KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQY 152 +R NP P V+W + + PL + ++Y + + D +L I + P D G YTC A N Sbjct: 117 VRSNPKPKVTWFKNGYRVPLDD-----IKYKQTSAD-TLEIAGLVPQDTGIYTCRAENAR 170 Query: 153 G 153 G Sbjct: 171 G 171 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 1998 EATLTPVNDPTMRVEWYCNGRPVQQGH-RFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056 E ++T ++P +V W+ NG V ++K T L+I +DTG Y C+A N Sbjct: 112 ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAEN 168 Query: 2057 AVG 2059 A G Sbjct: 169 ARG 171 Score = 33.1 bits (72), Expect = 5.7 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Query: 1343 RVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 +V WF NG + D L++ + P+D+G+YTC+A N G + L V Sbjct: 124 KVTWFKNGYRVPLDDIKYKQTSAD--TLEIAGLVPQDTGIYTCRAENARGHDTWNITLVV 181 Score = 32.7 bits (71), Expect = 7.5 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Query: 2526 AHYEARVVPVGDPSLRFEWYINGVELKMGS-RFRTTHDFGFVTLDINSVVANDAGLYMCK 2584 A E V +P + W+ NG + + +++ T TL+I +V D G+Y C+ Sbjct: 109 ASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCR 165 Query: 2585 AINRAG 2590 A N G Sbjct: 166 AENARG 171 >SB_26664| Best HMM Match : I-set (HMM E-Value=7.6e-06) Length = 434 Score = 46.8 bits (106), Expect = 4e-04 Identities = 49/187 (26%), Positives = 74/187 (39%), Gaps = 19/187 (10%) Query: 3039 QPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR 3098 +P + PP +F + I E ++A TG + V++W T+ Sbjct: 211 KPGETGSAPPRMKPIFAGPIFIKERRLARLP-KCEATGFPTPVLKWLKVYGTLPQGRAFV 269 Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158 + L I T+ DSG Y CRA+N G E+ +L P F Q+ Sbjct: 270 RDDS-----LLISSTRKADSGMYICRASNDLGVTEVFTQLVV-----AALPEFDIRPQDN 319 Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNH 3217 L G C+ V DP +++ W +G+ R TV D+G +V I + Sbjct: 320 TTLYTGDIFRANCS--GVGDPTLRVTWKKIDGKLPRFRA---TVRDWGELV--ITQVTSE 372 Query: 3218 DSGEYVC 3224 DSG Y C Sbjct: 373 DSGRYAC 379 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 8/85 (9%) Query: 1705 EVITQAPVFTMPMKDIRVAENQAAH----FEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760 EV TQ V +P DIR +N + F A VGDP LRV W + + + Sbjct: 299 EVFTQLVVAALPEFDIRPQDNTTLYTGDIFRANCSGVGDPTLRVTWKK--IDGKLPRFRA 356 Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTC 1785 T+ D+G + + V EDSG Y C Sbjct: 357 TVRDWGELVITQ--VTSEDSGRYAC 379 Score = 44.0 bits (99), Expect = 0.003 Identities = 56/240 (23%), Positives = 93/240 (38%), Gaps = 24/240 (10%) Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARF-EVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461 G P PIF P + E AR + E G P P++KW + + Q Sbjct: 216 GSAPPRMKPIFAG---PIFIKERRLARLPKCEATGFPTPVLKWLKVYGTLP-----QGRA 267 Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521 F L+I DS ++ A N G + LVV P F + Q Sbjct: 268 FVRDDSLLISSTRKADSGMYICRASNDLGVTEVFTQLVVAAL----------PEFDIRPQ 317 Query: 4522 -NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580 N + +G + R + G + V W K K+ P R + + L+I + +D Sbjct: 318 DNTTLYTGDIFRANCSGVGDPTLRVTWKKIDGKL-PRFRATVRDWG---ELVITQVTSED 373 Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640 SG+Y C+ G + +A +++ ++ K A PP I+ + ++G+A+ Sbjct: 374 SGRYACLLSTDGGIFKNEAFTTLNVINSEYNYKSHIIATITPPLSIQSVHCFRRSQGRAV 433 Score = 37.9 bits (84), Expect = 0.20 Identities = 43/171 (25%), Positives = 68/171 (39%), Gaps = 19/171 (11%) Query: 403 VTEGKMTRFD-CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461 + E ++ R C TG P P + W + + V + +L+I++ +DSG Sbjct: 232 IKERRLARLPKCEATGFPTPVLKWLKVYGTLPQG---RAFVRDD---SLLISSTRKADSG 285 Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREGEPVVLNARAVGTPTP 520 + C A N G T +L V P+F + + G+ N VG PT Sbjct: 286 MYICRASNDLGVTEVFTQLVV-----AALPEFDIRPQDNTTLYTGDIFRANCSGVGDPTL 340 Query: 521 RITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 R+TW+K DG +P + G L I + + D+ Y C G Sbjct: 341 RVTWKKIDGK--LPRFRATVRDWG---ELVITQVTSEDSGRYACLLSTDGG 386 Score = 37.5 bits (83), Expect = 0.26 Identities = 39/135 (28%), Positives = 57/135 (42%), Gaps = 18/135 (13%) Query: 3800 PQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859 P+G G+K + G AP + P FI + + + + E F V Sbjct: 199 PRGAKGDKGDRGKPGETGSAPPRMKPIFAGPIFIKERRLARLPKCEATGFPTPV------ 252 Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKA 3917 ++W + LP G + V D SL I DSG YICRA ND G E FT+ Sbjct: 253 ---LKWLKVYGTLPQGRAF--VRDD---SLLISSTRKADSGMYICRASNDLGVTEVFTQL 304 Query: 3918 TISCKKLPDIILQNQ 3932 ++ LP+ ++ Q Sbjct: 305 VVAA--LPEFDIRPQ 317 Score = 37.1 bits (82), Expect = 0.35 Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 8/84 (9%) Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR-TFHDFGIV 3340 P+F + QD T L G F A V DP L+V W KLP R+R T D+G + Sbjct: 310 PEFDIRPQDNTTLYTGDI--FRANCSGVGDPTLRVTWKKIDGKLP---RFRATVRDWGEL 364 Query: 3341 ILDILYCYEENSGEYECVATNKLG 3364 + I E+SG Y C+ + G Sbjct: 365 V--ITQVTSEDSGRYACLLSTDGG 386 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 8/77 (10%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLK-DGRPVEASSRITTFFNFGYV 967 PEF +D ++ G F A +GD TLRV W K DG+ + T ++G Sbjct: 310 PEFDIRPQDNTTLYTGDI--FRANCSGVGDPTLRVTWKKIDGKLPRFRA---TVRDWG-- 362 Query: 968 ALTIKSVTVHDAGHYTC 984 L I VT D+G Y C Sbjct: 363 ELVITQVTSEDSGRYAC 379 Score = 35.9 bits (79), Expect = 0.80 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 7/88 (7%) Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR-TVYD 3883 +V+ P+F + + +T + + F DP LR+ W + LP R+R TV D Sbjct: 305 VVAALPEFDIRPQDNTTLYTGDI-FRANCSGVGDPTLRVTWKKIDGKLP---RFRATVRD 360 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFG 3911 G L I V +EDSG Y C D G Sbjct: 361 WG--ELVITQVTSEDSGRYACLLSTDGG 386 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 5/88 (5%) Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696 P+F + + T + G I F VGDPT+++ W K + RF + R + L Sbjct: 310 PEFDIRPQDNTTLYTGDI-FRANCSGVGDPTLRVTWKKIDGKL---PRFRATVR-DWGEL 364 Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKA 724 + + +DSG Y C + G+ + +A Sbjct: 365 VITQVTSEDSGRYACLLSTDGGIFKNEA 392 Score = 35.5 bits (78), Expect = 1.1 Identities = 49/202 (24%), Positives = 81/202 (40%), Gaps = 22/202 (10%) Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF--SCKIVGKPLPTVQWYKGDKLIKPSK 4667 D+ KP + +APP + I + + + C+ G P P ++W K + + Sbjct: 208 DRGKPG-ETGSAPPRMKPIFAGPIFIKERRLARLPKCEATGFPTPVLKWLKVYGTLPQGR 266 Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727 F D+ +L IS D G Y C A N G V +L V + D + P Sbjct: 267 AF----VRDD-SLLISSTRKADSGMYICRASNDLGVTEVFTQLVVAALPEFD----IRPQ 317 Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQ--WLR-EGALIPETPDFQMIHEGNNAVLLIGNTY 4784 + +Y G F+ + PT++ W + +G L P F+ + L+I Sbjct: 318 DNTTLYTGD--IFRANCSGVGDPTLRVTWKKIDGKL----PRFRATVR-DWGELVITQVT 370 Query: 4785 EEDTGTFTCRATTAAGQVETSA 4806 ED+G + C +T G + A Sbjct: 371 SEDSGRYACLLSTDGGIFKNEA 392 Score = 35.5 bits (78), Expect = 1.1 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800 K + T P ++WL+ +P+ F + + + LLI +T + D+G + CRA+ G Sbjct: 242 KCEATGFPTPVLKWLKVYGTLPQGRAF--VRDDS---LLISSTRKADSGMYICRASNDLG 296 Query: 4801 QVETSAKLVV 4810 E +LVV Sbjct: 297 VTEVFTQLVV 306 Score = 35.1 bits (77), Expect = 1.4 Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 11/94 (11%) Query: 64 GRPGEP--SPPIFEQIFKNARFAQGGNAKFEGKLR--GNPTPVVSWTRKKAPLVECNKYS 119 G+PGE +PP + IF F + K G PTPV+ W + L + + Sbjct: 210 GKPGETGSAPPRMKPIFAGPIFIKERRLARLPKCEATGFPTPVLKWLKVYGTLPQGRAF- 268 Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 D SLLI D G Y C A N G Sbjct: 269 ------VRDDSLLISSTRKADSGMYICRASNDLG 296 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%) Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432 R +P+F P+ I+E + A + G PT ++W + + + Sbjct: 221 RMKPIFAGPIF----IKERRLARLP-KCEATGFPTPVLKWLKVYGTLPQGRAFVRDD--- 272 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458 S+ IS R D G+Y+CRASN LG Sbjct: 273 --SLLISSTRKADSGMYICRASNDLG 296 Score = 33.1 bits (72), Expect = 5.7 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 8/90 (8%) Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEW-FFNGKPLLHKNRFTPIYDFGYV 4031 P F + Q T+L + + C + VGDP ++V W +GK L + R T + D+G + Sbjct: 310 PEFDIRPQDNTTLYTGDIFRANC--SGVGDPTLRVTWKKIDGK--LPRFRAT-VRDWGEL 364 Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061 + V EDSG Y C + G+ + +A Sbjct: 365 VIT--QVTSEDSGRYACLLSTDGGIFKNEA 392 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 6/83 (7%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P F + +DN + G +C VGDPT+R+ W T+ D+G Sbjct: 310 PEFDIRPQDNTTLYTGDIFRANC--SGVGDPTLRVTWKKIDGKLPRFRA--TVRDWG--E 363 Query: 3755 LDIDYIYARDAGEYTCRATNKWG 3777 L I + + D+G Y C + G Sbjct: 364 LVITQVTSEDSGRYACLLSTDGG 386 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 4/63 (6%) Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852 F N DPTL++ W + LP R+++T + L IT EDSG Y C + Sbjct: 328 FRANCSGVGDPTLRVTWKKIDGKLP---RFRATVR-DWGELVITQVTSEDSGRYACLLST 383 Query: 2853 SKG 2855 G Sbjct: 384 DGG 386 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 6/57 (10%) Query: 2528 YEARVVPVGDPSLRFEWYINGVELKMGSRFR-TTHDFGFVTLDINSVVANDAGLYMC 2583 + A VGDP+LR W ++ K+ RFR T D+G L I V + D+G Y C Sbjct: 328 FRANCSGVGDPTLRVTW--KKIDGKL-PRFRATVRDWG--ELVITQVTSEDSGRYAC 379 >SB_24434| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1194 Score = 46.8 bits (106), Expect = 4e-04 Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 11/175 (6%) Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597 TG ++ W N D N + L+I A +G Y C A AR Sbjct: 205 TGNPVPEIVWFDNHNNEIADGTNGYRFQSHGRVLVIDRADESSAGAYTC-----ACRART 259 Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657 ++ V P T A PE+ D + QA + S I + L T +WY Sbjct: 260 SSKAVAHTKVVIKGPPVLT--ATPKPEVKLMRGDDLALVCQAKQTSEDISHQSLITFEWY 317 Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 + ++ + S + D+ LR+ D G Y+CVA ++ G T A+++ + Sbjct: 318 RNNQQLADSDKIAI----DDGNLRVKNVSDRDNGVYQCVARDNMGMSTAASRVMI 368 Score = 41.1 bits (92), Expect = 0.021 Identities = 47/231 (20%), Positives = 92/231 (39%), Gaps = 15/231 (6%) Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLKDKIVAEGQAIEFSCKIVGK 4649 S G+ D+ +++ K Q+ +A E++E P ++ G E C G Sbjct: 150 SVGDEYFDSHTMLTSDHGSKTTKEQSVLRDA--ELMEKPATLEVALRGARKELRCIPTGN 207 Query: 4650 PLPTVQWY--KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA-YNSAGRVTV 4706 P+P + W+ +++ + ++ + L I A G Y C ++ + Sbjct: 208 PVPEIVWFDNHNNEIADGTNGYRFQ--SHGRVLVIDRADESSAGAYTCACRARTSSKAVA 265 Query: 4707 AAKLKVTQPD--QADNLPALTPLR-DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763 K+ + P A P + +R D + Q Q I+ + T +W R + + Sbjct: 266 HTKVVIKGPPVLTATPKPEVKLMRGDDLALVCQAKQTSEDISHQSLITFEWYRNNQQLAD 325 Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814 + D I +GN L + N + D G + C A G ++++++K T Sbjct: 326 S-DKIAIDDGN---LRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIKGVT 372 Score = 39.1 bits (87), Expect = 0.086 Identities = 52/229 (22%), Positives = 98/229 (42%), Gaps = 32/229 (13%) Query: 267 KIAQKPRNSKLQ-EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 ++ +KP ++ GA + + +GNP P + WF N I + + L + Sbjct: 181 ELMEKPATLEVALRGARKELRCIPTGNPVPEIVWFDNHNNEIADGTNGYRFQSHGRVLVI 240 Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385 +S +G YT C + AV + V + +T T + E + + Sbjct: 241 DRADESSAGAYTC------ACRARTSSKAV---AHTKVVIKGPPVLTATPKPEVK-LMRG 290 Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445 + AL VCQ + +E ++ + W+ N++Q+ D + KI +++ Sbjct: 291 DDLAL------VCQAKQTSED--------ISHQSLITFEWYRNNQQLAD--SDKIAIDD- 333 Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV--IEKEQVVAPK 492 GN L + NV+ D+GV CVAR+ G + R+ + + ++AP+ Sbjct: 334 GN--LRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIKGVTCSAILAPR 380 Score = 38.3 bits (85), Expect = 0.15 Identities = 43/183 (23%), Positives = 70/183 (38%), Gaps = 21/183 (11%) Query: 406 GKMTRFDCRVTGRPYPEVTWFIN-DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464 G C TG P PE+ WF N + +I D N +S L+I S +G T Sbjct: 195 GARKELRCIPTGNPVPEIVWFDNHNNEIADGTNGYRF--QSHGRVLVIDRADESSAGAYT 252 Query: 465 CVARNKSGETAFQCRLNVIEKEQVV--APKFVERFSTLNVREGEPVVLNARAVGTPTP-- 520 C R ++ A VI+ V+ PK + + G+ + L +A T Sbjct: 253 CACRARTSSKAVAHTKVVIKGPPVLTATPK-----PEVKLMRGDDLALVCQAKQTSEDIS 307 Query: 521 -----RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575 W ++ + + ++ I DG L + D YQC A++ G + Sbjct: 308 HQSLITFEWYRNNQQLADSDKIAI-DDG---NLRVKNVSDRDNGVYQCVARDNMGMSTAA 363 Query: 576 ARL 578 +R+ Sbjct: 364 SRV 366 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 10/101 (9%) Query: 3557 PPEFTTTPS-DLILSENSSAHFECRLIPVND-----SSMRVEWFHNGKPLLTGSRVKTIN 3610 PP T TP ++ L C+ ++ S + EW+ N + L ++ I+ Sbjct: 274 PPVLTATPKPEVKLMRGDDLALVCQAKQTSEDISHQSLITFEWYRNNQQLADSDKI-AID 332 Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651 D L + V RD G+Y C A + G +T + ++ +KG Sbjct: 333 DGN---LRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIKG 370 Score = 35.9 bits (79), Expect = 0.80 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 4/48 (8%) Query: 2411 EWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 EW+RN + + DS +I D G ++ + +V D D GVY C A + +G Sbjct: 315 EWYRNNQQLADSDKIAI--DDG--NLRVKNVSDRDNGVYQCVARDNMG 358 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/103 (21%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPN-----LKIEWFKNGVTLTTGARLK 2692 ++ P+ T K KL+ G + L Q + ++ + EW++N L ++ Sbjct: 271 IKGPPVLTATPKPEVKLMRGDDLALVCQAKQTSEDISHQSLITFEWYRNNQQLADSDKI- 329 Query: 2693 STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 D G L + ++ + D+G+Y C A + +G + + + + I+ Sbjct: 330 -AIDDG--NLRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIK 369 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 4/62 (6%) Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134 +T EWY N +Q+ +++I D G L + +V D+GVY VAR+ G + ++ + Sbjct: 312 ITFEWYRNNQQLADSDKIAI--DDGN--LRVKNVSDRDNGVYQCVARDNMGMSTAASRVM 367 Query: 1135 VE 1136 ++ Sbjct: 368 IK 369 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 4/59 (6%) Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001 + EWY N + L K+ D G L + +V +RD+G+Y C A + G + +S V Sbjct: 312 ITFEWYRNNQQLADSD--KIAIDDG--NLRVKNVSDRDNGVYQCVARDNMGMSTAASRV 366 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 5/73 (6%) Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358 W++N Q+L +S+K I + LRV+N D+G Y +A + G + + ++ Sbjct: 316 WYRNNQQLADSDKIAI----DDGNLRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIKGV 371 Query: 359 TESYVQDQR-SQY 370 T S + R SQ+ Sbjct: 372 TCSAILAPRDSQF 384 >SB_59087| Best HMM Match : ig (HMM E-Value=1.5e-27) Length = 955 Score = 46.4 bits (105), Expect = 6e-04 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 9/99 (9%) Query: 4623 PEIIEPLKDKIVA--EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680 P I P K +I+ G + +C G P P +QWYK I+ + + E L Sbjct: 658 PRISTP-KSQILRLYRGTTLNQTCVSQGNPAPVIQWYK----IEMNGSVSLQTRVKEGRL 712 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719 I E ED G+Y CVA NS G + A L +T+ + A+ Sbjct: 713 LIDEMREEDFGNYSCVATNSRG--SDAVYLSITELESAE 749 Score = 43.2 bits (97), Expect = 0.005 Identities = 43/171 (25%), Positives = 61/171 (35%), Gaps = 18/171 (10%) Query: 413 CRVTGRPYPEVTWFIND---------RQIRDDYNHKILVNESGNHALMITNVTL-SDSGV 462 C V P VTW+ R R+ L+ G L+I + + SG Sbjct: 575 CLVNAHPEATVTWWAGSLKLNAITEQRTCRNSLRGYYLLRGRGGDTLVICDALHEAHSGW 634 Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522 +TC A N G L+++ ++ PK L + G + + G P P I Sbjct: 635 LTCTAENHKGTDQRSAYLDILVSPRISTPK----SQILRLYRGTTLNQTCVSQGNPAPVI 690 Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 W K I N + + T L I + D Y C A N GS A Sbjct: 691 QWYK----IEMNGSVSLQTRVKEGRLLIDEMREEDFGNYSCVATNSRGSDA 737 Score = 40.3 bits (90), Expect = 0.037 Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 18/128 (14%) Query: 411 FDCRVTGRPYPEVTWFINDRQIRDD---YN---------HKILVNESGNHALMITNVTL- 457 F C TG P PE+ WF + +++ D +N HK V++ N L + +V Sbjct: 247 FHCAATGFPLPEIRWFKDGKELLTDNCLWNCKHRRVYEKHKAGVHDV-NECLRVNDVKFP 305 Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV-G 516 D+GV TC A N A + +V P +R ++ V+ L + G Sbjct: 306 DDAGVYTCQATN---GVAVLPSTRSVRAVFLVPPVLDKRIGSIVVQSDTTPTLTCTILSG 362 Query: 517 TPTPRITW 524 P PR TW Sbjct: 363 YPLPRFTW 370 Score = 34.7 bits (76), Expect = 1.9 Identities = 45/214 (21%), Positives = 86/214 (40%), Gaps = 23/214 (10%) Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251 G++ ++ C + G T+ +EW ++GS FV + H T A Sbjct: 139 GESFNITCEVTSAGVSTLNIEW-----QKSIGS--------AFVRIPADH-TFAKKNALV 184 Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP 1311 + N A + + + + D + EQ + +L+ D ++ AP Sbjct: 185 LMFKN--APAMNQTYFKCVAKLSVPKDYKKEQGT-YVHILDPVPATISHFTTDDEIVLAP 241 Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQ--TMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369 S+ H T G + E R G + T W C + + H+ + + Sbjct: 242 DTSQDFHCAAT--GFPLP-EIRWFKDGKELLTDNCLWNCKHRRVYEKHKAGVHDVNECLR 298 Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403 ++ + +P+D+GVYTCQATN + ++ ++R + Sbjct: 299 VNDVK-FPDDAGVYTCQATNGVAVLPSTRSVRAV 331 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 13/105 (12%) Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG--------ARLKS 2693 P +H + D++V + P +I WFK+G L T R+ Sbjct: 225 PATISHFTTDDEIVLAPDTSQDFHCAATGFPLPEIRWFKDGKELLTDNCLWNCKHRRVYE 284 Query: 2694 TFDFGL----VTLSINSLR-NDDSGIYTCKATNLLGEAVSTASIK 2733 G+ L +N ++ DD+G+YTC+ATN + ST S++ Sbjct: 285 KHKAGVHDVNECLRVNDVKFPDDAGVYTCQATNGVAVLPSTRSVR 329 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 96 RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 +GNP PV+ W + +E N S+ + + LLI ++ D G Y+C A N G Sbjct: 683 QGNPAPVIQWYK-----IEMNG-SVSLQTRVKEGRLLIDEMREEDFGNYSCVATNSRG 734 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 4/82 (4%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 P I T K Q R++ G P P+I+WY+ I+ + + T + L+ Sbjct: 658 PRISTPKSQILRLYRGTTLNQTCVSQGNPAPVIQWYK----IEMNGSVSLQTRVKEGRLL 713 Query: 4470 IRQVFVEDSAVFAAVAENRGGT 4491 I ++ ED ++ VA N G+ Sbjct: 714 IDEMREEDFGNYSCVATNSRGS 735 Score = 32.3 bits (70), Expect = 9.9 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 7/53 (13%) Query: 2678 WFKNGVTLTTGARLKSTFDFGL-------VTLSINSLRNDDSGIYTCKATNLL 2723 W ++GVTLT + + DF L V+LS+ + +DSG+Y+C A ++ Sbjct: 479 WRRDGVTLTPTEDPRISIDFVLSNALSQEVSLSVANATVNDSGVYSCHADQMI 531 >SB_50854| Best HMM Match : ig (HMM E-Value=6.1e-27) Length = 770 Score = 46.4 bits (105), Expect = 6e-04 Identities = 39/171 (22%), Positives = 69/171 (40%), Gaps = 15/171 (8%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGM-------VVLEILGTKTTDSGTYSCRATN 3127 TG + I W YN T+ A+ + + L + + G Y CRA+N Sbjct: 247 TGYPAPNITWLYNNMTVRPGRHDMWHGAYYLNALDHRRLTLNLFAVTRDNQGIYMCRASN 306 Query: 3128 KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD-GQSAHFECTVVPVDDPD-MKIEW 3185 WG+ E+ + + + + P+ + + + G+++ CTV + + + + W Sbjct: 307 GWGKEELVLNVTVI-----ELPKLAVNSDSQFYVSHRGENSTLTCTVTGIRNGETITAHW 361 Query: 3186 YHNGQPMRHSTRIKTVS-DFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235 H R TR +T+S +VL + D G Y C +K G T Sbjct: 362 RHGSSASRGRTRTQTLSGGRARLVLFLEDVTASDGGSYSCGISSKEGTHAT 412 Score = 38.7 bits (86), Expect = 0.11 Identities = 41/172 (23%), Positives = 62/172 (36%), Gaps = 13/172 (7%) Query: 413 CRVTGRPYPEVTWFINDRQI---RDDYNHKILVNESGNHALMITN---VTLSDSGVVTCV 466 C VTG P P +TW N+ + R D H + +H + N VT + G+ C Sbjct: 244 CEVTGYPAPNITWLYNNMTVRPGRHDMWHGAYYLNALDHRRLTLNLFAVTRDNQGIYMCR 303 Query: 467 ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT---PTPRIT 523 A N G+ + VIE ++ + + + GE L G T Sbjct: 304 ASNGWGKEELVLNVTVIELPKLAVNSDSQFYVS---HRGENSTLTCTVTGIRNGETITAH 360 Query: 524 WQKDGVPIIPNPELRIHTDGGAS-TLDIPRAKASDAAWYQCTAQNVAGSTAT 574 W+ + + G A L + ASD Y C + G+ AT Sbjct: 361 WRHGSSASRGRTRTQTLSGGRARLVLFLEDVTASDGGSYSCGISSKEGTHAT 412 Score = 37.9 bits (84), Expect = 0.20 Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 11/105 (10%) Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR-------YRTSNDFGFAAL 1904 GP + G + C + YP PN + W +N ++ G Y + D L Sbjct: 230 GPLRWPLGSRQYLACEVTGYPAPN--ITWLYNNMTVRPGRHDMWHGAYYLNALDHRRLTL 287 Query: 1905 DILTVYGEDSGEYTCKAINNLG--QAVSSIRLNVQSKESIIRDSQ 1947 ++ V ++ G Y C+A N G + V ++ + K ++ DSQ Sbjct: 288 NLFAVTRDNQGIYMCRASNGWGKEELVLNVTVIELPKLAVNSDSQ 332 Score = 35.1 bits (77), Expect = 1.4 Identities = 41/206 (19%), Positives = 76/206 (36%), Gaps = 17/206 (8%) Query: 4619 ANAPPEIIEPLKDKIVAE---GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK-------Y 4668 A PP I PL G +C++ G P P + W + ++P + Y Sbjct: 216 ARGPPRINIPLTQPGPLRWPLGSRQYLACEVTGYPAPNITWLYNNMTVRPGRHDMWHGAY 275 Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728 + + TL + +++G Y C A N G+ + + V + L + + Sbjct: 276 YLNALDHRRLTLNLFAVTRDNQGIYMCRASNGWGKEELVLNVTVI---ELPKLAVNSDSQ 332 Query: 4729 DIVVYEGQPAQFK---TQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIGNTY 4784 V + G+ + T I + T W + Q + G VL + + Sbjct: 333 FYVSHRGENSTLTCTVTGIRNGETITAHWRHGSSASRGRTRTQTLSGGRARLVLFLEDVT 392 Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVV 4810 D G+++C ++ G T+ +VV Sbjct: 393 ASDGGSYSCGISSKEGTHATTFLVVV 418 Score = 35.1 bits (77), Expect = 1.4 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 9/76 (11%) Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-------YRTTHDFGYVALDILYTYA 2176 G R + C V P++T W +N +R G Y D + L++ Sbjct: 237 GSRQYLACEVTGYPAPNIT--WLYNNMTVRPGRHDMWHGAYYLNALDHRRLTLNLFAVTR 294 Query: 2177 EDSGTYMCKATNKLGE 2192 ++ G YMC+A+N G+ Sbjct: 295 DNQGIYMCRASNGWGK 310 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 9/76 (11%) Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG-------ARLKSTFDFGLVTLSINSLRN 2709 G YL +V PN I W N +T+ G A + D +TL++ ++ Sbjct: 237 GSRQYLACEVTGYPAPN--ITWLYNNMTVRPGRHDMWHGAYYLNALDHRRLTLNLFAVTR 294 Query: 2710 DDSGIYTCKATNLLGE 2725 D+ GIY C+A+N G+ Sbjct: 295 DNQGIYMCRASNGWGK 310 Score = 34.3 bits (75), Expect = 2.5 Identities = 27/106 (25%), Positives = 40/106 (37%), Gaps = 11/106 (10%) Query: 3690 EKPNPPRFTVEIKDN--IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR---- 3743 E PPR + + + P G + C V G P I W +N G Sbjct: 215 EARGPPRINIPLTQPGPLRWPLGSRQYLACEV--TGYPAPNITWLYNNMTVRPGRHDMWH 272 Query: 3744 -VHTLN--DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786 + LN D + L++ + + G Y CRA+N WG +T Sbjct: 273 GAYYLNALDHRRLTLNLFAVTRDNQGIYMCRASNGWGKEELVLNVT 318 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 4106 KARCPP---VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162 +AR PP + ++ P + G C VTG+P P + WL N T+ G R+ + + Sbjct: 215 EARGPPRINIPLTQPGPLRWPLGSRQYLACEVTGYPAPNITWLYNNMTVRPG-RHDMWHG 273 Query: 4163 GMY 4165 Y Sbjct: 274 AYY 276 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 4/66 (6%) Query: 1459 GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF-RPIHDFGYVA--LDIIDLIAEDSG 1515 GQ+V C + ++ +++W K+GQ VT G + G L I++ A+D+G Sbjct: 152 GQNVVLNCTVAAGRRAS-RMDWLKHGQGVTEGVTYCLDARGAGLTCAVLQIVNASAKDAG 210 Query: 1516 IYTCRA 1521 +Y C A Sbjct: 211 VYVCEA 216 >SB_33962| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 823 Score = 46.4 bits (105), Expect = 6e-04 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 9/99 (9%) Query: 4623 PEIIEPLKDKIVA--EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680 P I P K +I+ G + +C G P P +QWYK I+ + + E L Sbjct: 134 PRISTP-KSQILRLYRGTTLNQTCVSQGNPAPVIQWYK----IEMNGSVSLQTRVKEGRL 188 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719 I E ED G+Y CVA NS G + A L +T+ + A+ Sbjct: 189 LIDEMREEDFGNYSCVATNSRG--SDAVYLSITELESAE 225 Score = 43.2 bits (97), Expect = 0.005 Identities = 43/171 (25%), Positives = 61/171 (35%), Gaps = 18/171 (10%) Query: 413 CRVTGRPYPEVTWFIND---------RQIRDDYNHKILVNESGNHALMITNVTL-SDSGV 462 C V P VTW+ R R+ L+ G L+I + + SG Sbjct: 51 CLVNAHPEATVTWWAGSLKLNAITEQRTCRNSLRGYYLLRGRGGDTLVICDALHEAHSGW 110 Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522 +TC A N G L+++ ++ PK L + G + + G P P I Sbjct: 111 LTCTAENHKGTDQRSAYLDILVSPRISTPK----SQILRLYRGTTLNQTCVSQGNPAPVI 166 Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573 W K I N + + T L I + D Y C A N GS A Sbjct: 167 QWYK----IEMNGSVSLQTRVKEGRLLIDEMREEDFGNYSCVATNSRGSDA 213 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 96 RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 +GNP PV+ W + +E N S+ + + LLI ++ D G Y+C A N G Sbjct: 159 QGNPAPVIQWYK-----IEMNG-SVSLQTRVKEGRLLIDEMREEDFGNYSCVATNSRG 210 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 4/82 (4%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469 P I T K Q R++ G P P+I+WY+ I+ + + T + L+ Sbjct: 134 PRISTPKSQILRLYRGTTLNQTCVSQGNPAPVIQWYK----IEMNGSVSLQTRVKEGRLL 189 Query: 4470 IRQVFVEDSAVFAAVAENRGGT 4491 I ++ ED ++ VA N G+ Sbjct: 190 IDEMREEDFGNYSCVATNSRGS 211 >SB_27603| Best HMM Match : ig (HMM E-Value=2.9e-10) Length = 135 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 5/99 (5%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PP I P N EG++A G P P V W K + + +HE+ + L Sbjct: 2 PPTILPLPNNVTYFEGSEAVLTCSAEGTPFPIVYWSKQAK---SHGRHEL--ANRSMNLH 56 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYV 363 + N + GHYT A N G + + YL V +S V Sbjct: 57 LFNISRDHQGHYTCTAYNRAGTVNATLYLYVAPVDQSAV 95 Score = 46.0 bits (104), Expect = 8e-04 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 7/98 (7%) Query: 4622 PPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680 PP I+ PL + + EG +C G P P V W K K ++ +R+ + + Sbjct: 2 PPTIL-PLPNNVTYFEGSEAVLTCSAEGTPFPIVYWSKQAK--SHGRHELANRSMNLHLF 58 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718 IS + +G Y C AYN AG V L V DQ+ Sbjct: 59 NISR---DHQGHYTCTAYNRAGTVNATLYLYVAPVDQS 93 Score = 39.5 bits (88), Expect = 0.065 Identities = 23/91 (25%), Positives = 39/91 (42%), Gaps = 7/91 (7%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130 PP + N + +G A G P P+V W+++ K R+ ++ Sbjct: 2 PPTILPLPNNVTYFEGSEAVLTCSAEGTPFPIVYWSKQA-------KSHGRHELANRSMN 54 Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161 L + I +G YTCTA N+ G ++Y+ Sbjct: 55 LHLFNISRDHQGHYTCTAYNRAGTVNATLYL 85 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 6/68 (8%) Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464 EG C G P+P V W +Q + H+ L N S N L + N++ G T Sbjct: 16 EGSEAVLTCSAEGTPFPIVYW---SKQAKSHGRHE-LANRSMN--LHLFNISRDHQGHYT 69 Query: 465 CVARNKSG 472 C A N++G Sbjct: 70 CTAYNRAG 77 Score = 32.3 bits (70), Expect = 9.9 Identities = 15/35 (42%), Positives = 17/35 (48%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144 PP + LP+ VT EG A C G P P V W Sbjct: 2 PPTILPLPNNVTYFEGSEAVLTCSAEGTPFPIVYW 36 >SB_53873| Best HMM Match : Fibrinogen_C (HMM E-Value=0) Length = 660 Score = 46.0 bits (104), Expect = 8e-04 Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 19/169 (11%) Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703 C+ G P P V W K + + T+D+ TL I + D G Y C A + G Sbjct: 294 CRATGYPNPVVSWQKVFDKMPEGRTI----TSDQ-TLSILKTRRSDSGLYLCTATSPLGS 348 Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGALIP 4762 L V + + P R I Y G + +++ P I W R +G Sbjct: 349 SKSTTHLVVAVRPKF----TVRPPRKIKQYAGATVRVNCSASAEPPPKITWERCQGGT-- 402 Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 ++I G + VL N EDTGT+TC AT+ +TS + VK Sbjct: 403 -----RVIASGESLVLR--NLRYEDTGTYTCTATSRPLLAKTSFVIRVK 444 Score = 43.6 bits (98), Expect = 0.004 Identities = 40/130 (30%), Positives = 53/130 (40%), Gaps = 11/130 (8%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L I+ V L D G C + SG L V AP+ + GE + Sbjct: 236 LKISRVRLRDRGTYMCTVDSVSGMARALVTLKVRG-----APRINLDSGPVFAVRGENIT 290 Query: 510 L-NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568 L RA G P P ++WQK PE R T TL I + + SD+ Y CTA + Sbjct: 291 LPRCRATGYPNPVVSWQK---VFDKMPEGRTITSD--QTLSILKTRRSDSGLYLCTATSP 345 Query: 569 AGSTATRARL 578 GS+ + L Sbjct: 346 LGSSKSTTHL 355 Score = 43.2 bits (97), Expect = 0.005 Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 17/201 (8%) Query: 4612 PKPQ-TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670 PK + T + NAP +EP V E A F+C T+ W + D + K + Sbjct: 172 PKEERTGSINAPGIRVEP-SSLTVNENAAATFTCSSTTPGKATIMWSRVDGNMLGRKSIK 230 Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730 + + L+IS D G Y C + +G LKV + NL + + Sbjct: 231 VRQGK----LKISRVRLRDRGTYMCTVDSVSGMARALVTLKVRGAPRI-NLDS----GPV 281 Query: 4731 VVYEGQPAQF-KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789 G+ + + T P + W + + + P+ + I ++ L I T D+G Sbjct: 282 FAVRGENITLPRCRATGYPNPVVSWQK---VFDKMPEGRTI--TSDQTLSILKTRRSDSG 336 Query: 4790 TFTCRATTAAGQVETSAKLVV 4810 + C AT+ G +++ LVV Sbjct: 337 LYLCTATSPLGSSKSTTHLVV 357 Score = 43.2 bits (97), Expect = 0.005 Identities = 34/115 (29%), Positives = 49/115 (42%), Gaps = 12/115 (10%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 CR TG P P V+W +++ D + + + L I SDSG+ C A + G Sbjct: 294 CRATGYPNPVVSW----QKVFDKMPEGRTI--TSDQTLSILKTRRSDSGLYLCTATSPLG 347 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQK 526 + L V V PKF R + G V +N A P P+ITW++ Sbjct: 348 SSKSTTHLVV-----AVRPKFTVRPPRKIKQYAGATVRVNCSASAEPPPKITWER 397 Score = 36.3 bits (80), Expect = 0.61 Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 9/135 (6%) Query: 3527 GMEGTIDKIAALEGYSGTVDTLTPEAE---SGNPPEFTTTPSDLILSENSSAHFECRLIP 3583 G+ G++ + G G + P+ E S N P PS L ++EN++A F C Sbjct: 149 GVGGSVIAQKSDTGDDGKEPIVYPKEERTGSINAPGIRVEPSSLTVNENAAATFTCS--S 206 Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643 + W +L +K L+I V RD G Y C + G A Sbjct: 207 TTPGKATIMWSRVDGNMLGRKSIKVRQGK----LKISRVRLRDRGTYMCTVDSVSGMARA 262 Query: 3644 SCKLQVKGRQGIILE 3658 L+V+G I L+ Sbjct: 263 LVTLKVRGAPRINLD 277 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 5/66 (7%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 PN + W K + G + S TLSI R DSG+Y C AT+ LG + ST Sbjct: 300 PNPVVSWQKVFDKMPEGRTITSD-----QTLSILKTRRSDSGLYLCTATSPLGSSKSTTH 354 Query: 2732 IKIEDR 2737 + + R Sbjct: 355 LVVAVR 360 Score = 35.1 bits (77), Expect = 1.4 Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 15/122 (12%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L IL T+ +DSG Y C AT+ G ++ + L +P+FT G + Sbjct: 325 LSILKTRRSDSGLYLCTATSPLGSSKSTTHLVV-----AVRPKFTVRPPRKIKQYAGATV 379 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 C+ +P KI W + + TR+ S V+ ++ Y D+G Y C A Sbjct: 380 RVNCSASA--EPPPKITW----ERCQGGTRV-IASGESLVLRNLRY---EDTGTYTCTAT 429 Query: 3228 NK 3229 ++ Sbjct: 430 SR 431 Score = 35.1 bits (77), Expect = 1.4 Identities = 30/87 (34%), Positives = 39/87 (44%), Gaps = 8/87 (9%) Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGH 2228 L IL T DSG Y+C AT+ LG + +T L VA T P KI+Q G Sbjct: 325 LSILKTRRSDSGLYLCTATSPLGSSKSTTHLVVAVRPKF---TVRPP--RKIKQY--AGA 377 Query: 2229 STRIEVEEPKISPPRFVTE-LRGTTHV 2254 + R+ PP+ E +G T V Sbjct: 378 TVRVNCSASAEPPPKITWERCQGGTRV 404 Score = 33.9 bits (74), Expect = 3.2 Identities = 37/112 (33%), Positives = 47/112 (41%), Gaps = 9/112 (8%) Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHY-ECRIEPYPDPNMRVEWYFNG 1884 DS R V + V APR I +GP G++ CR YP+P V W Sbjct: 254 DSVSGMARALVTLKVRGAPR-INLDSGPVFAVRGENITLPRCRATGYPNPV--VSWQKVF 310 Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936 + G R TS+ L IL DSG Y C A + LG + S+ L V Sbjct: 311 DKMPEG-RTITSDQ----TLSILKTRRSDSGLYLCTATSPLGSSKSTTHLVV 357 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 12/80 (15%) Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW--FKNGQRLINSNKHEIITTHNH 320 V P + PR K GA + S P P++TW + G R+I S + Sbjct: 359 VRPKFTVRPPRKIKQYAGATVRVNCSASAEPPPKITWERCQGGTRVIASGE--------- 409 Query: 321 TTLRVRNTQKSDSGHYTLLA 340 +L +RN + D+G YT A Sbjct: 410 -SLVLRNLRYEDTGTYTCTA 428 >SB_50833| Best HMM Match : Thyroglobulin_1 (HMM E-Value=1.1e-08) Length = 280 Score = 46.0 bits (104), Expect = 8e-04 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQL--SGNPRPRVTWFKNGQRLI---NSNKHEIITTH 318 +P KI ++ S + A Q ++ G PRP+ W + G++L+ N H T H Sbjct: 17 TPAKINKQKTASTVHTSAGQQAMLKCFYDGIPRPQAIWMREGKQLLECKNCVTHIDNTKH 76 Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNG 345 TTLRV ++SD G Y N NG Sbjct: 77 GVTTLRVTPYRESDYGDYICKVRNENG 103 Score = 35.5 bits (78), Expect = 1.1 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 5/107 (4%) Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-- 3884 +TP K Q + TV S G + + P+ + W R GK L T D Sbjct: 16 NTPAKINKQKTASTVHTSAGQQAMLKCFYDGIPRPQAIWMREGKQLLECKNCVTHIDNTK 75 Query: 3885 -GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930 G +L + D G+YIC+ N+ G F TI+ + P ++ Q Sbjct: 76 HGVTTLRVTPYRESDYGDYICKVRNENG--FDSVTITLVEQPAVMSQ 120 Score = 35.5 bits (78), Expect = 1.1 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 3/76 (3%) Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG---GASTLDIPRAK 554 ST++ G+ +L G P P+ W ++G ++ H D G +TL + + Sbjct: 28 STVHTSAGQQAMLKCFYDGIPRPQAIWMREGKQLLECKNCVTHIDNTKHGVTTLRVTPYR 87 Query: 555 ASDAAWYQCTAQNVAG 570 SD Y C +N G Sbjct: 88 ESDYGDYICKVRNENG 103 Score = 35.1 bits (77), Expect = 1.4 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Query: 97 GNPTPVVSWTRKKAPLVEC-NKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 G P P W R+ L+EC N + N + G +L + D G+Y C RN+ G Sbjct: 46 GIPRPQAIWMREGKQLLECKNCVTHIDNTKHGVTTLRVTPYRESDYGDYICKVRNENG 103 >SB_48846| Best HMM Match : Pkinase_Tyr (HMM E-Value=8.1e-16) Length = 523 Score = 46.0 bits (104), Expect = 8e-04 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 1/88 (1%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDK-LIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692 VA G + +C G PLP V W K + LI+ + + S T+ +L + +D+G Sbjct: 7 VARGLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGL 66 Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADN 4720 Y C +N AG + L V + N Sbjct: 67 YVCRGWNLAGMASGNITLMVRVVEAGTN 94 Score = 41.1 bits (92), Expect = 0.021 Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLV-TLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 P ++ W KN L R++ T + LV +L + + +DD G+Y C+ NL G A Sbjct: 23 PLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASGNI 82 Query: 2731 SIKI 2734 ++ + Sbjct: 83 TLMV 86 Score = 40.3 bits (90), Expect = 0.037 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYV-SMTISHVRDEDEGVYMCRASNLLG 2458 G P +V W +N + + R+ +T + V S+ + V +D+G+Y+CR NL G Sbjct: 21 GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAG 76 Score = 40.3 bits (90), Expect = 0.037 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%) Query: 3590 RVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ 3648 RV W N + L+ RV+ ++ V LE+ GV D GLY C+ N G A+ + L Sbjct: 26 RVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASGNITLM 85 Query: 3649 VK 3650 V+ Sbjct: 86 VR 87 Score = 39.9 bits (89), Expect = 0.049 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG-ASTLDIPRAKAS 556 S + V G V L G+P PR+TW K+ +I +R ++ ++L++ + Sbjct: 3 SLMTVARGLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSD 62 Query: 557 DAAWYQCTAQNVAG 570 D Y C N+AG Sbjct: 63 DDGLYVCRGWNLAG 76 Score = 39.9 bits (89), Expect = 0.049 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 4/97 (4%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFV-TLDINSVVANDAGLYMCKAINRAGXXXX 2594 G P R W N EL R R T + V +L++ V ++D GLY+C+ N AG Sbjct: 21 GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASG 80 Query: 2595 XXXXXXXXXXXIIDQAM---RPESWEQIQLKEAAMNK 2628 + + R + W + + AMNK Sbjct: 81 NITLMVRVVEAGTNTTLVLTRKQGWGSVVFRVWAMNK 117 Score = 37.9 bits (84), Expect = 0.20 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%) Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNK-HEIITTHNHTTLRVRNTQKSDSGHYTL 338 G D +G+P PRVTW KN + LI + E T +L ++ D G Y Sbjct: 10 GLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVC 69 Query: 339 LAENPNG 345 N G Sbjct: 70 RGWNLAG 76 Score = 37.5 bits (83), Expect = 0.26 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 4/88 (4%) Query: 1317 LHNIETV-EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA-LDLLS 1374 ++++ TV G +V L C G RV W N + + R R E VA L+L Sbjct: 1 MNSLMTVARGLDVSLTCLF--TGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQG 58 Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRV 1402 V +D G+Y C+ N G A + L V Sbjct: 59 VSSDDDGLYVCRGWNLAGMASGNITLMV 86 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPEDSGTYTCRAINELGEAVT 1796 G P RV W +N + R+ + VA L ++ V+ +D G Y CR N G A Sbjct: 21 GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASG 80 Query: 1797 SSTLFVQ 1803 + TL V+ Sbjct: 81 NITLMVR 87 Score = 37.1 bits (82), Expect = 0.35 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Query: 1850 LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQSGHRYRTSNDFGFAALDILT 1908 +N ++ G C P P RV W N + +++ G TS A+L++ Sbjct: 1 MNSLMTVARGLDVSLTCLFTGSPLP--RVTWSKNSRELIRQGRVRETSETSLVASLELQG 58 Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 V +D G Y C+ N G A +I L V+ E+ Sbjct: 59 VSSDDDGLYVCRGWNLAGMASGNITLMVRVVEA 91 Score = 36.7 bits (81), Expect = 0.46 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA-LDIIHATSADT 1247 V+ G ++ L C G P RV W N R + R + + VA L++ +S D Sbjct: 7 VARGLDVSLTCLFT--GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDD 64 Query: 1248 GEYTVRAVNHLG--SAHTSAIVRVIE 1271 G Y R N G S + + +VRV+E Sbjct: 65 GLYVCRGWNLAGMASGNITLMVRVVE 90 Score = 35.1 bits (77), Expect = 1.4 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 1452 SIENVIEGQHVHFECKLEPVTDSNL-KVEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDL 1509 S+ V G V C T S L +V W KN + + R R + VA L++ + Sbjct: 3 SLMTVARGLDVSLTCLF---TGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGV 59 Query: 1510 IAEDSGIYTCRAVNLVG 1526 ++D G+Y CR NL G Sbjct: 60 SSDDDGLYVCRGWNLAG 76 Score = 35.1 bits (77), Expect = 1.4 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA-LDIDYIYARDAGEYTCRATNKWGSAT 3780 G P R+ W N R RV ++ +A L++ + + D G Y CR N G A+ Sbjct: 21 GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMAS 79 Score = 35.1 bits (77), Expect = 1.4 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA-MNFGWVYPEDSGEYLCRATNLYGM 4056 G P +V W N + L+ + R + VA + V +D G Y+CR NL GM Sbjct: 21 GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGM 77 Score = 34.7 bits (76), Expect = 1.9 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA-LDILYAYA 2044 N+ +T + + T P RV W N R + + R + T + VA L++ + Sbjct: 2 NSLMTVARGLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSS 61 Query: 2045 EDTGTYMCKATNAVGEA 2061 +D G Y+C+ N G A Sbjct: 62 DDDGLYVCRGWNLAGMA 78 Score = 34.7 bits (76), Expect = 1.9 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 4/102 (3%) Query: 3447 TDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPEDSGEYLCRAYNNYGEA- 3504 T P +V W N + L R R + V LE+ +D G Y+CR +N G A Sbjct: 20 TGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMAS 79 Query: 3505 --VTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGT 3544 +T V+ N L +G + ++ A+ Y + Sbjct: 80 GNITLMVRVVEAGTNTTLVLTRKQGWGSVVFRVWAMNKYGSS 121 Score = 34.3 bits (75), Expect = 2.5 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SLDITHTYEEDSGIYTCKATNSKGSAT 2858 P ++ W N++ L R + T + S V SL++ +D G+Y C+ N G A+ Sbjct: 23 PLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMAS 79 Score = 34.3 bits (75), Expect = 2.5 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 2944 KIEWYFNGKVLEQGSRFKLTSDFGFV-TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001 ++ W N + L + R + TS+ V +L+L V D G+Y C+ +N G A + T+ Sbjct: 26 RVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASGNITL 84 Score = 34.3 bits (75), Expect = 2.5 Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 1/53 (1%) Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVA-LDIMSCLPEDSGTYTCRAINALGEA 1661 +V W N++ L R ET+ VA L++ +D G Y CR N G A Sbjct: 26 RVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMA 78 Score = 33.9 bits (74), Expect = 3.2 Identities = 20/70 (28%), Positives = 28/70 (40%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V G C TG P P VTW N R++ + S +L + V+ D G+ Sbjct: 7 VARGLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGL 66 Query: 463 VTCVARNKSG 472 C N +G Sbjct: 67 YVCRGWNLAG 76 Score = 33.9 bits (74), Expect = 3.2 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAE 3133 TG + W N + + R+R +V LE+ G + D G Y CR N G A Sbjct: 20 TGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMAS 79 Query: 3134 ISVKL 3138 ++ L Sbjct: 80 GNITL 84 Score = 33.5 bits (73), Expect = 4.3 Identities = 17/66 (25%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-SLDMLSLNIQDSGEYTCRAVSATGVAET 722 G P ++ W KN + + R + SL++ ++ D G Y CR + G+A Sbjct: 21 GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASG 80 Query: 723 KAVLHV 728 L V Sbjct: 81 NITLMV 86 Score = 33.1 bits (72), Expect = 5.7 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Query: 2143 IDWFHNGQKIRAGHRYRTTHDFGYVA-LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 + W N +++ R R T + VA L++ ++D G Y+C+ N G A TL V Sbjct: 27 VTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASGNITLMV 86 Score = 32.3 bits (70), Expect = 9.9 Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVV-LDIAYTQNHDSGEYVCRAYNKYG 3231 P ++ W N + + R++ S+ V L++ + D G YVCR +N G Sbjct: 23 PLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAG 76 >SB_994| Best HMM Match : I-set (HMM E-Value=6e-15) Length = 189 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 3/97 (3%) Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH-NGQKIRAGHRYRTTHDF 2164 G V L + N DR EC+V + HL W NGQ I + R+ ++ Sbjct: 76 GSPKVVLVNTPRVRNAVVDDRVEIECQVTSNPEAHLY--WISDNGQVITSSGRFLVSNRN 133 Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 L I Y A DSG Y C A N +G + T + V Sbjct: 134 CNPTLTISYLLASDSGNYSCVANNSVGSSRQTVKIIV 170 Score = 42.3 bits (95), Expect = 0.009 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 1/81 (1%) Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLK-NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 N V ++ +VT +YW+ NG+ + R + + TL I DSG Sbjct: 90 NAVVDDRVEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSG 149 Query: 4583 KYECVAINSAGEARCDAECVV 4603 Y CVA NS G +R + +V Sbjct: 150 NYSCVANNSVGSSRQTVKIIV 170 Score = 42.3 bits (95), Expect = 0.009 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Query: 4640 IEFSCKIVGKPLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698 +E C++ P + W + ++I S F +S TL IS D G+Y CVA Sbjct: 97 VEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVAN 156 Query: 4699 NSAG--RVTVAAKLKVTQPDQADN 4720 NS G R TV +K + D N Sbjct: 157 NSVGSSRQTVKIIVKAVKFDHPPN 180 Score = 41.1 bits (92), Expect = 0.021 Identities = 20/74 (27%), Positives = 34/74 (45%) Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460 R+ +C+VT P + W ++ Q+ ++ N + N L I+ + SDS Sbjct: 89 RNAVVDDRVEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDS 148 Query: 461 GVVTCVARNKSGET 474 G +CVA N G + Sbjct: 149 GNYSCVANNSVGSS 162 Score = 40.7 bits (91), Expect = 0.028 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%) Query: 3713 VHFDCRVEPVGDPTMRIDWFH-NGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCR 3771 V +C+V +P + W NG+ + R N L I Y+ A D+G Y+C Sbjct: 97 VEIECQV--TSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCV 154 Query: 3772 ATNKWGSATTTAKITCSA 3789 A N GS+ T KI A Sbjct: 155 ANNSVGSSRQTVKIIVKA 172 Score = 39.9 bits (89), Expect = 0.049 Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Query: 1865 ECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923 EC++ P+ ++ W NG+V+ S R+ SN L I + DSG Y+C A N Sbjct: 100 ECQVTSNPEAHLY--WISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANN 157 Query: 1924 NLGQAVSSIRLNVQS 1938 ++G + ++++ V++ Sbjct: 158 SVGSSRQTVKIIVKA 172 Score = 39.5 bits (88), Expect = 0.065 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 4/93 (4%) Query: 1447 VTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK-NGQPVTIGHRFRPIHDFGYVALD 1505 V P+ + N + V EC++ +++L W NGQ +T RF + L Sbjct: 83 VNTPR-VRNAVVDDRVEIECQVTSNPEAHLY--WISDNGQVITSSGRFLVSNRNCNPTLT 139 Query: 1506 IIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS 1538 I L+A DSG Y+C A N VG+ + ++ ++ Sbjct: 140 ISYLLASDSGNYSCVANNSVGSSRQTVKIIVKA 172 Score = 38.3 bits (85), Expect = 0.15 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 5/89 (5%) Query: 1984 IKNAEVTEGHPVHLEATLTPVNDPTMRVEWYC-NGRPVQQGHRFKTTYDFGYVALDILYA 2042 ++NA V + V +E +T ++P + W NG+ + RF + L I Y Sbjct: 88 VRNAVVDDR--VEIECQVT--SNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYL 143 Query: 2043 YAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071 A D+G Y C A N+VG + T + V A Sbjct: 144 LASDSGNYSCVANNSVGSSRQTVKIIVKA 172 Score = 37.9 bits (84), Expect = 0.20 Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Query: 4739 QFKTQITSKIKPTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797 + + Q+TS + + W+ + G +I + F + + N L I D+G ++C A Sbjct: 98 EIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANN 157 Query: 4798 AAGQVETSAKLVVKS 4812 + G + K++VK+ Sbjct: 158 SVGSSRQTVKIIVKA 172 Score = 37.5 bits (83), Expect = 0.26 Identities = 17/63 (26%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 284 QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN-HTTLRVRNTQKSDSGHYTLLAEN 342 + + Q++ NP + W + ++I S+ +++ N + TL + SDSG+Y+ +A N Sbjct: 98 EIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANN 157 Query: 343 PNG 345 G Sbjct: 158 SVG 160 Score = 37.1 bits (82), Expect = 0.35 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 10/102 (9%) Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NG 3869 L++ +I + +V+TP ++++ V++ V EC+V +P+ + W NG Sbjct: 68 LQKSKIFAGSPKVVLVNTP-----RVRNAVVDDR--VEIECQVT--SNPEAHLYWISDNG 118 Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 +++ S R+ +L I Y+ A DSG Y C A N G Sbjct: 119 QVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANNSVG 160 Score = 36.7 bits (81), Expect = 0.46 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%) Query: 2789 DNIHFECNVEPSRDPTLKIEWFFNN-KPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847 D + EC V + +P + W +N + + S R+ ++ +L I++ DSG Y+ Sbjct: 95 DRVEIECQV--TSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYS 152 Query: 2848 CKATNSKGSA 2857 C A NS GS+ Sbjct: 153 CVANNSVGSS 162 Score = 36.3 bits (80), Expect = 0.61 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%) Query: 2662 LEAQVEPRTDPNLKIEWFK-NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKAT 2720 +E + + ++P + W NG +T+ R + TL+I+ L DSG Y+C A Sbjct: 97 VEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVAN 156 Query: 2721 NLLGEAVSTASIKIE 2735 N +G + T I ++ Sbjct: 157 NSVGSSRQTVKIIVK 171 Score = 33.5 bits (73), Expect = 4.3 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 5/83 (6%) Query: 1059 QSAHFEARVEPQSDLTMTVEWYF-----NGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113 ++A + RVE + +T E + NG+ ITS+ R + L I+ + A DS Sbjct: 89 RNAVVDDRVEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDS 148 Query: 1114 GVYTVVARNAAGEAQLSASMTVE 1136 G Y+ VA N+ G ++ + + V+ Sbjct: 149 GNYSCVANNSVGSSRQTVKIIVK 171 Score = 33.1 bits (72), Expect = 5.7 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Query: 2263 ECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINA 2322 ECQV + +L NG+ + S+ RF ++ +L I + + D+G YS A N+ Sbjct: 100 ECQVTSNPEAHL-YWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANNS 158 Query: 2323 LGHCTSAISMTVTA 2336 +G + + V A Sbjct: 159 VGSSRQTVKIIVKA 172 Score = 33.1 bits (72), Expect = 5.7 Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Query: 1739 DPKLRVEWLR-NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 +P+ + W+ NG I +S R + L + Y+ DSG Y+C A N +G + + Sbjct: 106 NPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANNSVGSSRQT 165 Query: 1798 STLFVQS 1804 + V++ Sbjct: 166 VKIIVKA 172 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/130 (22%), Positives = 47/130 (36%), Gaps = 6/130 (4%) Query: 3239 INCYGKGGVYLESLQPDSLAKIRELESLQGAQQ---QTPSTPSAEPPKFITQIQDVTKLV 3295 + CYG +L S+ S ++ S G Q + P + V V Sbjct: 33 LRCYGMNTCFLPSITAQSSYFLQAQCSYLGLYSGSLQKSKIFAGSPKVVLVNTPRVRNAV 92 Query: 3296 EGQSAHFEARLVPVDDPDLKVEWFY-NGKKLPHGHRYRTFHDFGIVILDILYCYEENSGE 3354 E ++ +P+ + W NG+ + R+ + L I Y +SG Sbjct: 93 VDDRVEIECQVT--SNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGN 150 Query: 3355 YECVATNKLG 3364 Y CVA N +G Sbjct: 151 YSCVANNSVG 160 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 657 ETRIEPVGDPTMKIEWLK-NGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVS 715 E + +P + W+ NGQ I +S RF R +L + L DSG Y+C A + Sbjct: 98 EIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANN 157 Query: 716 ATG 718 + G Sbjct: 158 SVG 160 Score = 32.3 bits (70), Expect = 9.9 Identities = 16/62 (25%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Query: 945 WLKD-GRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003 W+ D G+ + +S R LTI + D+G+Y+C A N++G + + + + Sbjct: 113 WISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANNSVGSSRQTVKIIVKA 172 Query: 1004 KK 1005 K Sbjct: 173 VK 174 >SB_56444| Best HMM Match : fn3 (HMM E-Value=1.2e-21) Length = 651 Score = 45.6 bits (103), Expect = 0.001 Identities = 55/225 (24%), Positives = 91/225 (40%), Gaps = 25/225 (11%) Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899 + AP FI+ L ++E + C P PN V WY RY+ +N Sbjct: 222 IRGAPSFISSLRSFYHVTENTNISVTCLASGRPAPN--VTWYTKTS------RYQLANGI 273 Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQ--AVSSIRLNVQSKESIIRDSQHESALEKIQY 1957 G A L + + SG Y C+AIN++ + + I +NVQ ++R + K + Sbjct: 274 GSATLSLSKIQRNQSGVYECRAINDVRRPPITTKITINVQ----LVRHLGF--VVLKPKA 327 Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWY-CN 2016 + S + S +KP+ +N G + L+ T P + WY + Sbjct: 328 PANLSPCCLVLFRSS---DKPEMLDSTQNTSSWNGRLLSLQCTAR--GSPYPYITWYKPD 382 Query: 2017 GRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEA 2061 G+ ++ G + G + Y D G Y C+A+N +G A Sbjct: 383 GQLIKVG---ACSIKDGSLLQIRTTQYTGDYGEYKCRASNLIGSA 424 Score = 45.6 bits (103), Expect = 0.001 Identities = 51/207 (24%), Positives = 84/207 (40%), Gaps = 28/207 (13%) Query: 4514 PSFTLTAQNV-NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 PSF + ++ +VT + + +G +V W + Q + N I G+ TL Sbjct: 226 PSFISSLRSFYHVTENTNISVTCLASGRPAPNVTWYTKTSRYQ--LANGI----GSATLS 279 Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP----KPQTKAANAP------ 4622 + + SG YEC AIN + +++ + KP+ A +P Sbjct: 280 LSKIQRNQSGVYECRAINDVRRPPITTKITINVQLVRHLGFVVLKPKAPANLSPCCLVLF 339 Query: 4623 -----PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD-KLIKPSKYFQMSRTAD 4676 PE+++ ++ G+ + C G P P + WYK D +LIK D Sbjct: 340 RSSDKPEMLDSTQNTSSWNGRLLSLQCTARGSPYPYITWYKPDGQLIKVG----ACSIKD 395 Query: 4677 EYTLRI-SEAFPEDEGDYKCVAYNSAG 4702 L+I + + D G+YKC A N G Sbjct: 396 GSLLQIRTTQYTGDYGEYKCRASNLIG 422 Score = 41.1 bits (92), Expect = 0.021 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 8/97 (8%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 ++ AP F + L+S+ + E ++ + R PN + W+ T +R + Sbjct: 222 IRGAPSFISSLRSFYHVTENTNISVTCLASGRPAPN--VTWY------TKTSRYQLANGI 273 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 G TLS++ ++ + SG+Y C+A N + T I I Sbjct: 274 GSATLSLSKIQRNQSGVYECRAINDVRRPPITTKITI 310 Score = 37.5 bits (83), Expect = 0.26 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%) Query: 391 APQFVKVCQD-RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449 AP F+ + VTE C +GRP P VTW+ + + L N G+ Sbjct: 225 APSFISSLRSFYHVTENTNISVTCLASGRPAPNVTWYTKTSRYQ-------LANGIGSAT 277 Query: 450 LMITNVTLSDSGVVTCVARN 469 L ++ + + SGV C A N Sbjct: 278 LSLSKIQRNQSGVYECRAIN 297 Score = 37.5 bits (83), Expect = 0.26 Identities = 49/218 (22%), Positives = 77/218 (35%), Gaps = 22/218 (10%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754 P F ++ V E + C G P + W+ SR N G Sbjct: 226 PSFISSLRSFYHVTENTNISVTCLAS--GRPAPNVTWY------TKTSRYQLANGIGSAT 277 Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814 L + I +G Y CRA N T KIT + QL + + +K Sbjct: 278 LSLSKIQRNQSGVYECRAINDVRRPPITTKITINV--------QLVRHLGFVVLKPKAPA 329 Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLP 3873 +S S P+ + ++ + + +C + P I WY+ +G+L+ Sbjct: 330 NLSPCCLVLFRSSDKPEMLDSTQNTSSWNGRLLSLQCTA--RGSPYPYITWYKPDGQLIK 387 Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 G ++ D + + Y D GEY CRA N G Sbjct: 388 VGAC--SIKDGSLLQIRTTQ-YTGDYGEYKCRASNLIG 422 Score = 37.1 bits (82), Expect = 0.35 Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 14/114 (12%) Query: 3830 PKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 P FI+ ++S + V E+ + C + P + WY RY+ +G + Sbjct: 226 PSFISSLRSFYHVTENTNISVTCLASGRPAPN--VTWYTKTS------RYQLANGIGSAT 277 Query: 3889 LDILYVYAEDSGEYICRAVNDFGED--FTKATIS---CKKLPDIILQNQVPRGM 3937 L + + SG Y CRA+ND TK TI+ + L ++L+ + P + Sbjct: 278 LSLSKIQRNQSGVYECRAINDVRRPPITTKITINVQLVRHLGFVVLKPKAPANL 331 Score = 36.3 bits (80), Expect = 0.61 Identities = 49/192 (25%), Positives = 71/192 (36%), Gaps = 20/192 (10%) Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595 G P+ WY SR++ + G TL ++ + N +G+Y C+AIN Sbjct: 252 GRPAPNVTWYTKT------SRYQLANGIGSATLSLSKIQRNQSGVYECRAIN------DV 299 Query: 2596 XXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLV 2655 I Q +R + ++ K A N P V P L S Sbjct: 300 RRPPITTKITINVQLVRHLGFVVLKPK-APANLSPCCLVLFRSSDKP---EMLDSTQNTS 355 Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFK-NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714 L Q R P I W+K +G + GA S D L+ + D G Sbjct: 356 SWNGRLLSLQCTARGSPYPYITWYKPDGQLIKVGA--CSIKDGSLLQIRTTQY-TGDYGE 412 Query: 2715 YTCKATNLLGEA 2726 Y C+A+NL+G A Sbjct: 413 YKCRASNLIGSA 424 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P++ +N+ G Q G+P P +TW+K +LI K + + + L++ Sbjct: 345 PEMLDSTQNTSSWNGRLLSLQCTARGSPYPYITWYKPDGQLI---KVGACSIKDGSLLQI 401 Query: 326 RNTQ-KSDSGHYTLLAEN 342 R TQ D G Y A N Sbjct: 402 RTTQYTGDYGEYKCRASN 419 Score = 34.3 bits (75), Expect = 2.5 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Query: 96 RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155 RG+P P ++W + L++ S++ G + + GD GEY C A N G A Sbjct: 369 RGSPYPYITWYKPDGQLIKVGACSIK----DGSLLQIRTTQYTGDYGEYKCRASNLIGSA 424 Query: 156 ICSVYI 161 +++ Sbjct: 425 EAVIHV 430 Score = 33.9 bits (74), Expect = 3.2 Identities = 26/112 (23%), Positives = 50/112 (44%), Gaps = 10/112 (8%) Query: 1426 DTSRYKKTDIIDESVTIK--PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN 1483 D + Y+ T + ++ I+ P F++ +S +V E ++ C N V W+ Sbjct: 206 DPTSYRFTALRVWNLKIRGAPSFISSLRSFYHVTENTNISVTCLASGRPAPN--VTWY-- 261 Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535 T R++ + G L + + SG+Y CRA+N V ++ ++T Sbjct: 262 ----TKTSRYQLANGIGSATLSLSKIQRNQSGVYECRAINDVRRPPITTKIT 309 Score = 33.9 bits (74), Expect = 3.2 Identities = 12/41 (29%), Positives = 20/41 (48%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432 P+ + Q+ G++ C G PYP +TW+ D Q+ Sbjct: 345 PEMLDSTQNTSSWNGRLLSLQCTARGSPYPYITWYKPDGQL 385 Score = 33.5 bits (73), Expect = 4.3 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 8/83 (9%) Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432 R P F L++ ++ E C + G P V W+ +SR + G Sbjct: 223 RGAPSFISSLRSFYHVTENTNISVTC--LASGRPAPNVTWYTK------TSRYQLANGIG 274 Query: 2433 YVSMTISHVRDEDEGVYMCRASN 2455 ++++S ++ GVY CRA N Sbjct: 275 SATLSLSKIQRNQSGVYECRAIN 297 Score = 33.1 bits (72), Expect = 5.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 2958 SRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYN 2990 SR++L + G TL L + SG+Y C+A N Sbjct: 265 SRYQLANGIGSATLSLSKIQRNQSGVYECRAIN 297 Score = 32.3 bits (70), Expect = 9.9 Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 10/112 (8%) Query: 1282 EQAIEQIQLLEDAARRTKQVRE-DITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGD 1339 ++ + + +++ + R +R ++ + AP F +L + V E TN+ + C G Sbjct: 196 DEKVYLVAIMDPTSYRFTALRVWNLKIRGAPSFISSLRSFYHVTENTNISVTCLAS--GR 253 Query: 1340 QTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQL 1391 V W+ KT R++ A L L + SGVY C+A N + Sbjct: 254 PAPNVTWYT-----KTS-RYQLANGIGSATLSLSKIQRNQSGVYECRAINDV 299 >SB_29125| Best HMM Match : I-set (HMM E-Value=1.8e-09) Length = 108 Score = 45.6 bits (103), Expect = 0.001 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 4/73 (5%) Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698 ++ C G P+P++ W + LI+PSK ++ + TL I D G Y+CVA Sbjct: 37 SVSIHCNATGNPVPSITWSRSGALIEPSKRIKIMGS----TLVIVGTLWSDTGSYECVAS 92 Query: 4699 NSAGRVTVAAKLK 4711 N AG ++ LK Sbjct: 93 NGAGTDRKSSFLK 105 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 5/83 (6%) Query: 4515 SFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 S LT N+N V + TG + W ++G ++P R KI+ TL+I Sbjct: 21 SHALTIGDNLNTLISTSVSIHCNATGNPVPSITWSRSGALIEPSKRIKIMGS----TLVI 76 Query: 4574 LEAYPQDSGKYECVAINSAGEAR 4596 + D+G YECVA N AG R Sbjct: 77 VGTLWSDTGSYECVASNGAGTDR 99 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 4/72 (5%) Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559 LN V ++ A G P P ITW + G I P+ ++I STL I SD Sbjct: 30 LNTLISTSVSIHCNATGNPVPSITWSRSGALIEPSKRIKIM----GSTLVIVGTLWSDTG 85 Query: 560 WYQCTAQNVAGS 571 Y+C A N AG+ Sbjct: 86 SYECVASNGAGT 97 Score = 35.9 bits (79), Expect = 0.80 Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 5/60 (8%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C TG P P +TW + I KI+ L+I SD+G CVA N +G Sbjct: 42 CNATGNPVPSITWSRSGALIEPSKRIKIM-----GSTLVIVGTLWSDTGSYECVASNGAG 96 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 4/64 (6%) Query: 290 SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349 +GNP P +TW ++G + S + +I+ +TL + T SD+G Y +A N G Sbjct: 45 TGNPVPSITWSRSGALIEPSKRIKIM----GSTLVIVGTLWSDTGSYECVASNGAGTDRK 100 Query: 350 SGYL 353 S +L Sbjct: 101 SSFL 104 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 4/56 (7%) Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130 TG+ I W +G IE S RI+ + + L I+GT +D+G+Y C A+N G Sbjct: 45 TGNPVPSITWSRSGALIEPSKRIKIMGS----TLVIVGTLWSDTGSYECVASNGAG 96 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 4/59 (6%) Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808 P+I W R GALI + +++ + L+I T DTG++ C A+ AG S+ L Sbjct: 50 PSITWSRSGALIEPSKRIKIM----GSTLVIVGTLWSDTGSYECVASNGAGTDRKSSFL 104 >SB_53160| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 292 Score = 45.2 bits (102), Expect = 0.001 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 8/116 (6%) Query: 2619 IQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEW 2678 ++++ ++ P D V+ AP FT+ L S + E V + R PN I W Sbjct: 146 VKIRTSSSPLSPSASWDLNVKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPN--ITW 203 Query: 2679 FKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 V T+G+ + G TLS+ ++ +G+Y C+A N +G T +I I Sbjct: 204 ----VNKTSGSPV--AHGTGSATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITI 253 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 10/104 (9%) Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896 ++ V AP F + L+ ++E C P PN + W K S + T Sbjct: 162 DLNVKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPN--ITWV--NKTSGSPVAHGT- 216 Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQS 1938 G A L +L + +G Y C+AIN++G+ +I +NVQS Sbjct: 217 ---GSATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITINVQS 257 Score = 39.1 bits (87), Expect = 0.086 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 11/88 (12%) Query: 489 VAPKFVERFSTL-NVREGEPVVLNARAVGTPTPRITW--QKDGVPIIPNPELRIHTDGGA 545 VAP F S+ +V E + V + A G P P ITW + G P+ H G A Sbjct: 167 VAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNITWVNKTSGSPV-------AHGTGSA 219 Query: 546 STLDIPRAKASDAAWYQCTAQNVAGSTA 573 TL + + + A YQC A N G A Sbjct: 220 -TLSLLKIQRHQAGVYQCQAINDVGRGA 246 Score = 36.7 bits (81), Expect = 0.46 Identities = 31/108 (28%), Positives = 41/108 (37%), Gaps = 12/108 (11%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRPFATGSRVHTLNDFGF 3752 P FT + + DV E V C G P I W + +G P A G+ G Sbjct: 169 PAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNITWVNKTSGSPVAHGT--------GS 218 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800 L + I AG Y C+A N G T IT + + +LP Sbjct: 219 ATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITINVQSIFRSSCKLP 266 Score = 35.5 bits (78), Expect = 1.1 Identities = 27/110 (24%), Positives = 45/110 (40%), Gaps = 9/110 (8%) Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496 D +V + P F + S +V E V C N+ +G PV Sbjct: 162 DLNVKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNITWVNKTSGSPVA-------- 213 Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST 1546 H G L ++ + +G+Y C+A+N VG ++ +T + I RS+ Sbjct: 214 HGTGSATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITI-NVQSIFRSS 262 Score = 35.5 bits (78), Expect = 1.1 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 8/87 (9%) Query: 390 LAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448 +AP F + RDV E C +GRP P +TW +N + + + +G+ Sbjct: 167 VAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNITW-VNKT------SGSPVAHGTGSA 219 Query: 449 ALMITNVTLSDSGVVTCVARNKSGETA 475 L + + +GV C A N G A Sbjct: 220 TLSLLKIQRHQAGVYQCQAINDVGRGA 246 Score = 35.1 bits (77), Expect = 1.4 Identities = 33/152 (21%), Positives = 54/152 (35%), Gaps = 13/152 (8%) Query: 2307 CVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPE 2366 C P D + G TS + S++ E L KIR S+ P Sbjct: 105 CAPNDTDTIYKGRLYFYGDFTSCSGVVEIRNASVVDEKSY---LVKIRT--SSSPLSPSA 159 Query: 2367 IPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT 2426 + + P FT L + ++ E C G P + W + +S Sbjct: 160 SWDLNVKVAPAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNITW------VNKTSGSP 211 Query: 2427 KTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458 H G ++++ ++ GVY C+A N +G Sbjct: 212 VAHGTGSATLSLLKIQRHQAGVYQCQAINDVG 243 Score = 34.3 bits (75), Expect = 2.5 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 13/102 (12%) Query: 1304 DITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGDQTMRVEWF--CNGKPIKTGHRFR 1360 D+ V AP F+ +L + V E +V + C G + W +G P+ Sbjct: 162 DLNVKVAPAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNITWVNKTSGSPV------- 212 Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402 A+ L LL + +GVY CQA N +G + A+ + Sbjct: 213 -AHGTGSATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITI 253 Score = 33.9 bits (74), Expect = 3.2 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 15/100 (15%) Query: 1710 APVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR--NGVPIEASNRLTTMHDFG 1766 AP FT + R VAEN G P + W+ +G P+ H G Sbjct: 168 APAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNITWVNKTSGSPVA--------HGTG 217 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQS 1804 L++ + +G Y C+AIN++G A+T + T+ VQS Sbjct: 218 SATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITINVQS 257 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 9/87 (10%) Query: 3826 VSTPPKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884 V P F + + S V E++ V C + P I W P H Sbjct: 165 VKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPN--ITWVNKTSGSPVAH------GT 216 Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911 G +L +L + +G Y C+A+ND G Sbjct: 217 GSATLSLLKIQRHQAGVYQCQAINDVG 243 >SB_51910| Best HMM Match : ig (HMM E-Value=4.9e-05) Length = 562 Score = 45.2 bits (102), Expect = 0.001 Identities = 40/129 (31%), Positives = 54/129 (41%), Gaps = 6/129 (4%) Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAF 4686 P+K I A+ C G P P V W K G L + S + + +Y +I E Sbjct: 419 PMKQYIQYNTTALVQGCNAQGTPSPVVTWTKNGVPLDRYSVMVPVRPHSTQY--QIPEVQ 476 Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQIT 4745 DEG+Y C Y G V + K+ TQ D LP+ D EG+ A F T Sbjct: 477 KSDEGNYTCSVYQHMGYVDMVFKVS-TQLVVYD-LPSFRREPSDQTRREGEDAVFNCVAT 534 Query: 4746 SKIKPTIQW 4754 KP ++W Sbjct: 535 GIPKPHLEW 543 Score = 44.8 bits (101), Expect = 0.002 Identities = 34/114 (29%), Positives = 43/114 (37%), Gaps = 7/114 (6%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C G P P VTW N + D Y+ + V I V SD G TC G Sbjct: 435 CNAQGTPSPVVTWTKNGVPL-DRYSVMVPVRPHSTQ-YQIPEVQKSDEGNYTCSVYQHMG 492 Query: 473 --ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524 + F+ ++ + P F S REGE V N A G P P + W Sbjct: 493 YVDMVFKVSTQLVVYD---LPSFRREPSDQTRREGEDAVFNCVATGIPKPHLEW 543 Score = 42.7 bits (96), Expect = 0.007 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 10/89 (11%) Query: 66 PGEPSPPIFEQI-FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124 P S P+ + I + QG NA+ G P+PVV+WT+ PL ++YS+ Sbjct: 413 PHSGSLPMKQYIQYNTTALVQGCNAQ------GTPSPVVTWTKNGVPL---DRYSVMVPV 463 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 + I ++ DEG YTC+ G Sbjct: 464 RPHSTQYQIPEVQKSDEGNYTCSVYQHMG 492 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/129 (23%), Positives = 53/129 (41%), Gaps = 7/129 (5%) Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501 V S +H+L + +SD+G+ G + V + K +++T Sbjct: 371 VRISADHSLEMNAAKISDAGIYMFHGSQNVGYFTVYIKALVFPHSGSLPMKQYIQYNTTA 430 Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561 + +G A GTP+P +TW K+GVP + + + ++ IP + SD Y Sbjct: 431 LVQG------CNAQGTPSPVVTWTKNGVP-LDRYSVMVPVRPHSTQYQIPEVQKSDEGNY 483 Query: 562 QCTAQNVAG 570 C+ G Sbjct: 484 TCSVYQHMG 492 Score = 37.9 bits (84), Expect = 0.20 Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 2/73 (2%) Query: 266 PKIAQKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 P P +Q A Q G P P VTW KNG L + + H+ T + Sbjct: 413 PHSGSLPMKQYIQYNTTALVQGCNAQGTPSPVVTWTKNGVPLDRYSVMVPVRPHS-TQYQ 471 Query: 325 VRNTQKSDSGHYT 337 + QKSD G+YT Sbjct: 472 IPEVQKSDEGNYT 484 Score = 35.5 bits (78), Expect = 1.1 Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 12/133 (9%) Query: 1668 IVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQD----EVITQAPVF----TMPMKD 1719 IV K + + + H + ++ D Y H +Q+ V +A VF ++PMK Sbjct: 364 IVEKDKEVRISADHSLEM-NAAKISDAGIYMFHGSQNVGYFTVYIKALVFPHSGSLPMKQ 422 Query: 1720 IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPED 1779 + N A + G P V W +NGVP++ + + + + V D Sbjct: 423 Y-IQYNTTALVQG-CNAQGTPSPVVTWTKNGVPLDRYSVMVPVRPHS-TQYQIPEVQKSD 479 Query: 1780 SGTYTCRAINELG 1792 G YTC +G Sbjct: 480 EGNYTCSVYQHMG 492 >SB_39770| Best HMM Match : TolA (HMM E-Value=0.33) Length = 732 Score = 45.2 bits (102), Expect = 0.001 Identities = 41/170 (24%), Positives = 80/170 (47%), Gaps = 12/170 (7%) Query: 4232 EKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKL-QELENEQVI 4290 E T EE +LQ +G D +L+ + +E E E ++ RK+ EE + + +ELE EQ Sbjct: 277 EDTLEEEAMLQ-EGKQDALRKLRQTIQREREEE--EAALRKEKEEALDAVREELEEEQEE 333 Query: 4291 KESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDP 4350 KESRLR+ Q + + +S+A+ +E + EE + ++ + + D Sbjct: 334 KESRLRDEKEQ--------SLRKLRESLAREHEKEKRKIEEEYHAALDEQREKLDKEKDA 385 Query: 4351 SESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERV 4400 + K + +QK+T+ +K + +T + + +T+ ++ Sbjct: 386 EIEKLQQKNQYELQQKKTELIEKHEKAMEDVLTELDQVQNAELGETKRKM 435 >SB_13504| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 4924 Score = 45.2 bits (102), Expect = 0.001 Identities = 52/196 (26%), Positives = 76/196 (38%), Gaps = 34/196 (17%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 P F T V G+ V L + + W + + VQ + GT L Sbjct: 4229 PRLFNQTISRWTVEEGEHVVLGCEAQSVTKVIYTWRRGDEVVQK-------ADHGTLELP 4281 Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632 ++ ++G Y C A N G A E ++ KP+ + EP+ K Sbjct: 4282 SIKR--SEAGMYTCEAANHKGSAEYHYEIIIEY-------KPEL--------LEEPISFK 4324 Query: 4633 IVAEG-QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED-- 4689 + G + FSC G P P V+WY +P Y ++S + R+ P+D Sbjct: 4325 LALYGGKGATFSCLATGNPQPRVEWY-----YRP-LYSKLSFKLPDNDSRLVYIEPDDVM 4378 Query: 4690 -EGDYKCVAYNSAGRV 4704 G Y CVA NS GRV Sbjct: 4379 RSGFYYCVASNSRGRV 4394 Score = 36.7 bits (81), Expect = 0.46 Identities = 25/130 (19%), Positives = 53/130 (40%), Gaps = 6/130 (4%) Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500 +V ++ + L + ++ S++G+ TC A N G + + + K +++ + + Sbjct: 4269 VVQKADHGTLELPSIKRSEAGMYTCEAANHKGSAEYHYEIIIEYKPELLEEPISFKLALY 4328 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 G+ + A G P PR+ W P+ ++ D + + I + + Sbjct: 4329 G---GKGATFSCLATGNPQPRVEWYYR--PLYSKLSFKL-PDNDSRLVYIEPDDVMRSGF 4382 Query: 561 YQCTAQNVAG 570 Y C A N G Sbjct: 4383 YYCVASNSRG 4392 Score = 36.7 bits (81), Expect = 0.46 Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 9/124 (7%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 LE+ K +++G Y+C A N G AE ++ K + + + + L G+ A Sbjct: 4278 LELPSIKRSEAGMYTCEAANHKGSAEYHYEIIIEYKPELLEEPISFKL----ALYGGKGA 4333 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 F C + +P ++EWY+ +P+ K + D ++ I SG Y C A Sbjct: 4334 TFSC--LATGNPQPRVEWYY--RPLYSKLSFK-LPDNDSRLVYIEPDDVMRSGFYYCVAS 4388 Query: 3228 NKYG 3231 N G Sbjct: 4389 NSRG 4392 Score = 36.3 bits (80), Expect = 0.61 Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 9/79 (11%) Query: 493 FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552 F + S V EGE VVL A TW++ E+ D G TL++P Sbjct: 4232 FNQTISRWTVEEGEHVVLGCEAQSVTKVIYTWRR-------GDEVVQKADHG--TLELPS 4282 Query: 553 AKASDAAWYQCTAQNVAGS 571 K S+A Y C A N GS Sbjct: 4283 IKRSEAGMYTCEAANHKGS 4301 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 6/102 (5%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 GK F C TG P P V W+ R + + K+ N+S + I + SG C Sbjct: 4330 GKGATFSCLATGNPQPRVEWYY--RPLYSKLSFKLPDNDS--RLVYIEPDDVMRSGFYYC 4385 Query: 466 VARNKSGE-TAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506 VA N G + + RL+++ V P+ F+ + E Sbjct: 4386 VASNSRGRVVSEEGRLDILRSRGAV-PRMAVVFNVTACAQDE 4426 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Query: 266 PKIAQKPRNSKLQ--EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323 P++ ++P + KL G A F +GNP+PRV W+ R + S + ++ + Sbjct: 4314 PELLEEPISFKLALYGGKGATFSCLATGNPQPRVEWY---YRPLYSKLSFKLPDNDSRLV 4370 Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVT 349 + SG Y +A N G +V+ Sbjct: 4371 YIEPDDVMRSGFYYCVASNSRGRVVS 4396 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 11/90 (12%) Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715 EG+HV L + + T K+ + T G + D G TL + S++ ++G+Y Sbjct: 4243 EGEHVVLGCEAQSVT----KVIY-----TWRRGDEVVQKADHG--TLELPSIKRSEAGMY 4291 Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESL 2745 TC+A N G A I IE + LL E + Sbjct: 4292 TCEAANHKGSAEYHYEIIIEYKPELLEEPI 4321 Score = 33.5 bits (73), Expect = 4.3 Identities = 13/43 (30%), Positives = 26/43 (60%) Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659 LE+ + + +AG+YTC+A N G A ++ ++ + ++ EP Sbjct: 4278 LELPSIKRSEAGMYTCEAANHKGSAEYHYEIIIEYKPELLEEP 4320 Score = 32.3 bits (70), Expect = 9.9 Identities = 26/121 (21%), Positives = 45/121 (37%), Gaps = 12/121 (9%) Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693 V EG+ + C+ W +GD++++ AD TL + + G Y Sbjct: 4241 VEEGEHVVLGCEAQSVTKVIYTWRRGDEVVQK---------ADHGTLELPSIKRSEAGMY 4291 Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753 C A N G ++ + + P L +Y G+ A F T +P ++ Sbjct: 4292 TCEAANHKGSAEYHYEIIIEYKPELLEEPISFKL---ALYGGKGATFSCLATGNPQPRVE 4348 Query: 4754 W 4754 W Sbjct: 4349 W 4349 >SB_31858| Best HMM Match : I-set (HMM E-Value=3.7e-08) Length = 229 Score = 45.2 bits (102), Expect = 0.001 Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 14/121 (11%) Query: 455 VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNA 512 VTL+D G+ CV + A + I+ + V P F + +E V L Sbjct: 112 VTLADGGLYHCVTEHARECAALATKTVNIQVNSIGSVPPNITTSFKNMIFKENATVRLTC 171 Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572 +A G P P + W D RI GG++TL++ +A A + Y+C A N A Sbjct: 172 QATGNPAPDVYWTMD--------RRRI---GGSNTLEL-KASADNMGVYECVAANGAAPD 219 Query: 573 A 573 A Sbjct: 220 A 220 Score = 43.2 bits (97), Expect = 0.005 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 18/133 (13%) Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532 V + D ++ V E+ +C+A + G VPP+ T + +N+ VR Sbjct: 112 VTLADGGLYHCVTEH---ARECAALATKTVNIQVNSIGSVPPNITTSFKNMIFKENATVR 168 Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592 L + TG DVYW + +++ G L L+A + G YECVA N A Sbjct: 169 LTCQATGNPAPDVYWTMDRRRI------------GGSNTLELKASADNMGVYECVAANGA 216 Query: 4593 GEARCDAECVVSL 4605 DA+ V+L Sbjct: 217 AP---DAKASVTL 226 Score = 40.3 bits (90), Expect = 0.037 Identities = 33/122 (27%), Positives = 46/122 (37%), Gaps = 21/122 (17%) Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 D G Y CV ++ EC ATK + PP I K+ I E Sbjct: 116 DGGLYHCVTEHAR-------ECAAL--ATKTVNIQVNSIGSVPPNITTSFKNMIFKENAT 166 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 + +C+ G P P V W + I S ++ +AD + G Y+CVA N Sbjct: 167 VRLTCQATGNPAPDVYWTMDRRRIGGSNTLELKASAD------------NMGVYECVAAN 214 Query: 4700 SA 4701 A Sbjct: 215 GA 216 Score = 37.5 bits (83), Expect = 0.26 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 1/56 (1%) Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314 S+G V PP I +N +E A + Q +GNP P V W + +R+ SN E+ Sbjct: 144 SIGSV-PPNITTSFKNMIFKENATVRLTCQATGNPAPDVYWTMDRRRIGGSNTLEL 198 >SB_19207| Best HMM Match : ig (HMM E-Value=1.2e-11) Length = 418 Score = 45.2 bits (102), Expect = 0.001 Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 6/118 (5%) Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 SFT +N+ + +G V L +++ K P ++ WLKNG+ + + KI L I Sbjct: 131 SFTAKVENITMIAGMQVTLKCRLSRKKIPFNITWLKNGQPMTS--KYKIRRFKWGSRLRI 188 Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-KPQTKAANAPPEIIEPLK 4630 A +D+G Y CV + E R A +S+ T +P + A P +P K Sbjct: 189 KRARQEDAGNYTCVVRANGQEVR--AAGWLSILGTSSRPTMKKVYTAKPPTSTTKPTK 244 Score = 38.7 bits (86), Expect = 0.11 Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 11/135 (8%) Query: 271 KPRNSKLQEGADAQFQVQLSGNPRP-RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQ 329 K N + G + +LS P +TW KNGQ + ++K++I + LR++ + Sbjct: 135 KVENITMIAGMQVTLKCRLSRKKIPFNITWLKNGQPM--TSKYKIRRFKWGSRLRIKRAR 192 Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAV----ESPTESYVQDQRSQYITDTQQRETEERIEI 385 + D+G+YT + + +G+L++ PT V + T ++ +E+ Sbjct: 193 QEDAGNYTCVVRANGQEVRAAGWLSILGTSSRPTMKKVYTAKPPTSTTKPTKKVKEKFPR 252 Query: 386 SEKALAPQFVKVCQD 400 E P KVC + Sbjct: 253 CE----PYRGKVCAE 263 Score = 37.1 bits (82), Expect = 0.35 Identities = 40/165 (24%), Positives = 67/165 (40%), Gaps = 14/165 (8%) Query: 1440 VTIKPRFVTRPKSIENV--IEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH 1497 + + + V+ +EN+ I G V +C+L + W KNGQP+T ++ R Sbjct: 123 IRVTMKAVSFTAKVENITMIAGMQVTLKCRLSR-KKIPFNITWLKNGQPMTSKYKIRRF- 180 Query: 1498 DFGYVALDIIDLIAEDSGIYTC---------RAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548 +G L I ED+G YTC RA + S R T + T Sbjct: 181 KWG-SRLRIKRARQEDAGNYTCVVRANGQEVRAAGWLSILGTSSRPTMKKVYTAKPPTST 239 Query: 1549 EAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQ 1593 ++++ R + +R + E +P+ TS + I EG+ Sbjct: 240 TKPTKKVKEKFPRCEPYRGKVCAEFMYGSPVYATSRHHQRIIEGK 284 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699 +A FT +++ ++ G V L+ ++ + P I W KNG +T+ +++ F +G Sbjct: 128 KAVSFTAKVENIT-MIAGMQVTLKCRLSRKKIP-FNITWLKNGQPMTSKYKIRR-FKWGS 184 Query: 2700 VTLSINSLRNDDSGIYTC 2717 L I R +D+G YTC Sbjct: 185 -RLRIKRARQEDAGNYTC 201 Score = 35.5 bits (78), Expect = 1.1 Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 11/114 (9%) Query: 4637 GQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695 G + C++ K +P + W K + + SKY ++ R LRI A ED G+Y C Sbjct: 144 GMQVTLKCRLSRKKIPFNITWLKNGQPMT-SKY-KIRRFKWGSRLRIKRARQEDAGNYTC 201 Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749 V + V A L + + VY +P T+ T K+K Sbjct: 202 VVRANGQEVRAAGWLSILGTSSRPTMKK--------VYTAKPPTSTTKPTKKVK 247 Score = 35.1 bits (77), Expect = 1.4 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 5/93 (5%) Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LD 2834 F + + NI G + +C + + P I W N +P+ S +YK F + S L Sbjct: 132 FTAKVENITMIAGMQVTLKCRLSRKKIP-FNITWLKNGQPMTS--KYKIRR-FKWGSRLR 187 Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867 I +ED+G YTC + +G L G Sbjct: 188 IKRARQEDAGNYTCVVRANGQEVRAAGWLSILG 220 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 3/55 (5%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997 + WLK+G+P+ + +I F +G L IK DAG+YTC A GQ +A Sbjct: 162 ITWLKNGQPMTSKYKIRR-FKWG-SRLRIKRARQEDAGNYTC-VVRANGQEVRAA 213 Score = 33.9 bits (74), Expect = 3.2 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 3/55 (5%) Query: 804 VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858 + W K+G+P+T+ +I F +G L I R EDAG+YT V G+ + A Sbjct: 162 ITWLKNGQPMTSKYKIRR-FKWGS-RLRIKRARQEDAGNYTC-VVRANGQEVRAA 213 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765 V +A FT +++I + + RL P + WL+NG P+ + ++ + Sbjct: 125 VTMKAVSFTAKVENITMIAGMQVTLKCRLSRKKIP-FNITWLKNGQPMTSKYKIRRFK-W 182 Query: 1766 GYVALNMKYVNPEDSGTYTC 1785 G L +K ED+G YTC Sbjct: 183 GS-RLRIKRARQEDAGNYTC 201 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 3/89 (3%) Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114 ++ G + R+ + + + W NG+ +TS +I+ + +G L I R ED+G Sbjct: 141 MIAGMQVTLKCRLS-RKKIPFNITWLKNGQPMTSKYKIRRFK-WGS-RLRIKRARQEDAG 197 Query: 1115 VYTVVARNAAGEAQLSASMTVETRSSIDT 1143 YT V R E + + +++ SS T Sbjct: 198 NYTCVVRANGQEVRAAGWLSILGTSSRPT 226 >SB_18521| Best HMM Match : ig (HMM E-Value=7.5e-11) Length = 1033 Score = 45.2 bits (102), Expect = 0.001 Identities = 40/158 (25%), Positives = 64/158 (40%), Gaps = 16/158 (10%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C TGRP P VTWF++D+++ + N + N + V+ C ARN G Sbjct: 293 CFPTGRPTPNVTWFVDDKELVTSTKQYNISNYGRVLKVAFGNAVM----VIKCTARNTVG 348 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG-TPTPRITWQKDGVPI 531 + R V +P R + + V+ GE + L +P + W +G I Sbjct: 349 SKSAITR--------VYSPTGSVRPTKIFVKSGESLTLTVGIADLLASPHVAWLFNGKTI 400 Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 P + + + +L I + SD+ YQ VA Sbjct: 401 SPASRISLSIN---KSLVIKFLQVSDSGIYQSLLNGVA 435 Score = 33.9 bits (74), Expect = 3.2 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 14/131 (10%) Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDK-LIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691 I+ + +E C G+P P V W+ DK L+ +K + +S Y + AF Sbjct: 282 ILKPEENVELHCFPTGRPTPNVTWFVDDKELVTSTKQYNIS----NYGRVLKVAFGNAVM 337 Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI-KP 4750 KC A N+ G + +A +V P ++ P + I V G+ I + P Sbjct: 338 VIKCTARNTVG--SKSAITRVYSP-----TGSVRPTK-IFVKSGESLTLTVGIADLLASP 389 Query: 4751 TIQWLREGALI 4761 + WL G I Sbjct: 390 HVAWLFNGKTI 400 Score = 32.7 bits (71), Expect = 7.5 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559 L ++ E V L+ G PTP +TW D ++ + + + + L + A + Sbjct: 281 LILKPEENVELHCFPTGRPTPNVTWFVDDKELVTSTK-QYNISNYGRVLKV--AFGNAVM 337 Query: 560 WYQCTAQNVAGSTATRARLY 579 +CTA+N GS + R+Y Sbjct: 338 VIKCTARNTVGSKSAITRVY 357 >SB_44830| Best HMM Match : I-set (HMM E-Value=1.1e-08) Length = 480 Score = 44.8 bits (101), Expect = 0.002 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 I+ CK G P T W K K I + Q +++ LR+ + P D GDY CV N Sbjct: 231 IKLKCKAEGTPPLTFTWLKNGKPITHRR-LQPGLKTNQWYLRLRDLVPADTGDYTCVVSN 289 Query: 4700 SAGRVTVAAKLKV 4712 G++ L+V Sbjct: 290 PYGQINHTYTLQV 302 Score = 44.0 bits (99), Expect = 0.003 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQA 1387 + L+C+ + G + W NGKPI T R +P + + L L + P D+G YTC Sbjct: 231 IKLKCKAE--GTPPLTFTWLKNGKPI-THRRLQPGLKTNQWYLRLRDLVPADTGDYTCVV 287 Query: 1388 TNQLGEAVTSCALRVI 1403 +N G+ + L+V+ Sbjct: 288 SNPYGQINHTYTLQVV 303 Score = 42.3 bits (95), Expect = 0.009 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590 ++L K GT P+ WLKNGK + L+ + Y L + + P D+G Y CV N Sbjct: 231 IKLKCKAEGTPPLTFTWLKNGKPITHRRLQPGLKTNQWY-LRLRDLVPADTGDYTCVVSN 289 Query: 4591 SAGE 4594 G+ Sbjct: 290 PYGQ 293 Score = 41.9 bits (94), Expect = 0.012 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 6/87 (6%) Query: 3972 PPRFVTQIQSQTSLVEM---ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028 PP F Q + + + + T K +C+ G P + W NGKP+ H+ R P Sbjct: 209 PPYFAQQQKMKGTFIAWPAWHTIKLKCKAE--GTPPLTFTWLKNGKPITHR-RLQPGLKT 265 Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYG 4055 + + P D+G+Y C +N YG Sbjct: 266 NQWYLRLRDLVPADTGDYTCVVSNPYG 292 Score = 39.1 bits (87), Expect = 0.086 Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 10/120 (8%) Query: 237 RESITKRYVGESDVQISTEIDRSLGPVS-----PPKIAQKPRNSKLQEGADAQFQVQLS- 290 RE++ + + +DV + + R + ++ PP AQ+ + A ++L Sbjct: 176 RETLNENAMHATDVSLVLLLLRGIAALATSSRGPPYFAQQQKMKGTFIAWPAWHTIKLKC 235 Query: 291 ---GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347 G P TW KNG+ + + + T N LR+R+ +D+G YT + NP G I Sbjct: 236 KAEGTPPLTFTWLKNGKPITHRRLQPGLKT-NQWYLRLRDLVPADTGDYTCVVSNPYGQI 294 Score = 37.1 bits (82), Expect = 0.35 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P L WL+NG PI RL L ++ + P D+G YTC N G+ + Sbjct: 239 GTPPLTFTWLKNGKPI-THRRLQPGLKTNQWYLRLRDLVPADTGDYTCVVSNPYGQINHT 297 Query: 1798 STLFV 1802 TL V Sbjct: 298 YTLQV 302 Score = 36.7 bits (81), Expect = 0.46 Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%) Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996 G L WLK+G+P+ R+ L ++ + D G YTC N GQ + Sbjct: 239 GTPPLTFTWLKNGKPI-THRRLQPGLKTNQWYLRLRDLVPADTGDYTCVVSNPYGQINHT 297 Query: 997 ANLTIVT 1003 L +VT Sbjct: 298 YTLQVVT 304 Score = 35.9 bits (79), Expect = 0.80 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Query: 1462 VHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521 + +CK E L W KNG+P+T R +P L + DL+ D+G YTC Sbjct: 231 IKLKCKAEGTPP--LTFTWLKNGKPIT-HRRLQPGLKTNQWYLRLRDLVPADTGDYTCVV 287 Query: 1522 VNLVG 1526 N G Sbjct: 288 SNPYG 292 Score = 35.9 bits (79), Expect = 0.80 Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 90 KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149 K + K G P +W + P+ ++ +T L ++ + P D G+YTC Sbjct: 232 KLKCKAEGTPPLTFTWLKNGKPITHRR---LQPGLKTNQWYLRLRDLVPADTGDYTCVVS 288 Query: 150 NQYGE 154 N YG+ Sbjct: 289 NPYGQ 293 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 6/92 (6%) Query: 3694 PPRFTVEIKDN---IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750 PP F + K I P + C+ E G P + W NG+P T R+ Sbjct: 209 PPYFAQQQKMKGTFIAWPAWHTIKLKCKAE--GTPPLTFTWLKNGKPI-THRRLQPGLKT 265 Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 L + + D G+YTC +N +G T Sbjct: 266 NQWYLRLRDLVPADTGDYTCVVSNPYGQINHT 297 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254 I L+C+ E G P + W NG+ +T R + L + ADTG+YT Sbjct: 231 IKLKCKAE--GTPPLTFTWLKNGKPIT-HRRLQPGLKTNQWYLRLRDLVPADTGDYTCVV 287 Query: 1255 VNHLGSAHTSAIVRVIERSDIVTD 1278 N G + + ++V+ S + D Sbjct: 288 SNPYGQINHTYTLQVVTVSGTLPD 311 >SB_37776| Best HMM Match : fn3 (HMM E-Value=1.4e-22) Length = 1296 Score = 44.4 bits (100), Expect = 0.002 Identities = 51/215 (23%), Positives = 73/215 (33%), Gaps = 26/215 (12%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTL 4571 PPS + + V V RL G +V W + G ++ P + +LE +L Sbjct: 37 PPSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPPDKFVVLERG---SL 93 Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLK 4630 LI + D G Y C N G KP P E P Sbjct: 94 LIRKVKRSDMGTYVCTPSNYIGAG---------------KPGTTNLVVQVVPTFTEVPSS 138 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690 V G+ I F C V + +P+V W + K F + L I D Sbjct: 139 VVSVRVGEEIRFKCSAVSETVPSVSWR------RVGKAFSNRTQTSKGLLTILGVQTVDH 192 Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725 G+Y+CVA G+ L V + A++ Sbjct: 193 GEYECVAETDKGKAVHTTTLNVISVPSRPTITAVS 227 Score = 42.3 bits (95), Expect = 0.009 Identities = 49/181 (27%), Positives = 68/181 (37%), Gaps = 16/181 (8%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT-WFINDRQIRDDYNHKILVNESGNHAL 450 P + + V E R C G P EVT W ++ K +V E G+ L Sbjct: 38 PSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPP--DKFVVLERGS--L 93 Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE-RFSTLNVREGEPVV 509 +I V SD G C N G V++ V P F E S ++VR GE + Sbjct: 94 LIRKVKRSDMGTYVCTPSNYIGAGKPGTTNLVVQ----VVPTFTEVPSSVVSVRVGEEIR 149 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 AV P ++W++ G R T G L I + D Y+C A+ Sbjct: 150 FKCSAVSETVPSVSWRRVGKAF----SNRTQTSKG--LLTILGVQTVDHGEYECVAETDK 203 Query: 570 G 570 G Sbjct: 204 G 204 Score = 40.7 bits (91), Expect = 0.028 Identities = 52/202 (25%), Positives = 79/202 (39%), Gaps = 23/202 (11%) Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI-KWYRENFPIKNSPDFQIHTFSTKSIL 4468 PP V E+ AR +G P + KW R + F + + L Sbjct: 37 PPSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPPDKFVV---LERGSL 93 Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVT 4526 +IR+V D + N G K + NLVV+ V P+FT + + V+V Sbjct: 94 LIRKVKRSDMGTYVCTPSNYIGAGKPGTTNLVVQ----------VVPTFTEVPSSVVSVR 143 Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586 G+ +R V W + GK N+ G T+L ++ D G+YEC Sbjct: 144 VGEEIRFKCSAVSETVPSVSWRRVGKAFS----NRTQTSKGLLTILGVQTV--DHGEYEC 197 Query: 4587 VAINSAGEA-RCDAECVVSLPA 4607 VA G+A V+S+P+ Sbjct: 198 VAETDKGKAVHTTTLNVISVPS 219 Score = 39.5 bits (88), Expect = 0.065 Identities = 50/195 (25%), Positives = 70/195 (35%), Gaps = 19/195 (9%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV-QWYK-GDKLIKPSKYFQMSRTADEYT 4679 PP II V E C G P V +W + G +L P K+ + R + Sbjct: 37 PPSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPPDKFVVLERGS---- 92 Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT--PLRDIVVYEGQP 4737 L I + D G Y C N G V Q +P T P + V G+ Sbjct: 93 LLIRKVKRSDMGTYVCTPSNYIGAGKPGTTNLVVQV-----VPTFTEVPSSVVSVRVGEE 147 Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797 +FK S+ P++ W R G F + + +L I D G + C A T Sbjct: 148 IRFKCSAVSETVPSVSWRRVGKA------FSNRTQTSKGLLTILGVQTVDHGEYECVAET 201 Query: 4798 AAGQVETSAKLVVKS 4812 G+ + L V S Sbjct: 202 DKGKAVHTTTLNVIS 216 Score = 37.5 bits (83), Expect = 0.26 Identities = 36/133 (27%), Positives = 52/133 (39%), Gaps = 12/133 (9%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I K +D GTY C +N G + V P FT ++ ++ G+ Sbjct: 93 LLIRKVKRSDMGTYVCTPSNYIGAGKPGTTNLVVQVV----PTFTEVPSSVVSVRVGEEI 148 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227 F+C+ V P + W G+ S R +T +L I Q D GEY C A Sbjct: 149 RFKCSAVSETVPS--VSWRRVGKAF--SNRTQTSKG----LLTILGVQTVDHGEYECVAE 200 Query: 3228 NKYGEDFTRATIN 3240 G+ T+N Sbjct: 201 TDKGKAVHTTTLN 213 Score = 36.3 bits (80), Expect = 0.61 Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 11/103 (10%) Query: 3825 IVSTPPKFITQIKSH--TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882 +V P F T++ S +V E +RF+C + P + W R GK + RT Sbjct: 125 VVQVVPTF-TEVPSSVVSVRVGEEIRFKCSAVSETVPS--VSWRRVGKAFSN----RTQT 177 Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925 G L IL V D GEY C A D G+ T++ +P Sbjct: 178 SKGL--LTILGVQTVDHGEYECVAETDKGKAVHTTTLNVISVP 218 Score = 35.1 bits (77), Expect = 1.4 Identities = 31/104 (29%), Positives = 42/104 (40%), Gaps = 8/104 (7%) Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897 + V P F + + G+ ++C P+ V W GK + RT Sbjct: 124 LVVQVVPTFTEVPSSVVSVRVGEEIRFKCSAVSETVPS--VSWRRVGKAFSN----RTQT 177 Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 G L IL V D GEY C A + G+AV + LNV S S Sbjct: 178 SKGL--LTILGVQTVDHGEYECVAETDKGKAVHTTTLNVISVPS 219 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 8/94 (8%) Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107 P FT V +V + G+ ++ S + S + W GK S+R +T + Sbjct: 130 PTFTEVPSSVVSVRVGEEIRFKCSAVSETVPS--VSWRRVGKAF--SNRTQTSKG----L 181 Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141 L ILG +T D G Y C A G+A + L + Sbjct: 182 LTILGVQTVDHGEYECVAETDKGKAVHTTTLNVI 215 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 8/93 (8%) Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168 P F +S+ +++ G+ F+C +++ ++ W G+ +R +T+ Sbjct: 130 PTFTEVPSSVVSVRVGEEIRFKCSA--VSETVPSVSWRRVGKAF--SNRTQTSKGL---- 181 Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 L IL D G Y C A G+AV+T TL V Sbjct: 182 LTILGVQTVDHGEYECVAETDKGKAVHTTTLNV 214 Score = 34.3 bits (75), Expect = 2.5 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 8/93 (8%) Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479 P FT S++ ++R GE F+ P+ V W GK+ RT G + Sbjct: 130 PTFTEVPSSVVSVRVGEEIRFKCSAVSETVPS--VSWRRVGKAFSN----RTQTSKG--L 181 Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512 L I D GEY C A + G+AV T ++ V Sbjct: 182 LTILGVQTVDHGEYECVAETDKGKAVHTTTLNV 214 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 8/95 (8%) Query: 390 LAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448 + P F +V V G+ RF C P V+W R++ ++++ ++ Sbjct: 128 VVPTFTEVPSSVVSVRVGEEIRFKCSAVSETVPSVSW----RRVGKAFSNR---TQTSKG 180 Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483 L I V D G CVA G+ LNVI Sbjct: 181 LLTILGVQTVDHGEYECVAETDKGKAVHTTTLNVI 215 Score = 33.5 bits (73), Expect = 4.3 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 6/84 (7%) Query: 71 PPIFEQIFKNARFAQGGNAKFEGKLRGNP-TPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129 PP I + +A+ GNP T V WTR L +K+ + + G Sbjct: 37 PPSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPPDKFVVL---ERG-- 91 Query: 130 SLLIKQIGPGDEGEYTCTARNQYG 153 SLLI+++ D G Y CT N G Sbjct: 92 SLLIRKVKRSDMGTYVCTPSNYIG 115 >SB_25692| Best HMM Match : I-set (HMM E-Value=2e-20) Length = 104 Score = 44.4 bits (100), Expect = 0.002 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C VTG P P +TW N +++ + + ++ N N +L++ V+ SD G TC ARN G Sbjct: 36 CPVTGVPAPTITWSRNGQEMPANGDGYLVTN---NGSLILEKVSSSDIGRYTCTARNAFG 92 Query: 473 ETAFQCRLNVI 483 + +NV+ Sbjct: 93 KDNANSTVNVM 103 Score = 42.3 bits (95), Expect = 0.009 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 V L+ G P P ITW ++G + N + + T+ G+ L+ + +SD Y CTA+N Sbjct: 32 VTLHCPVTGVPAPTITWSRNGQEMPANGDGYLVTNNGSLILE--KVSSSDIGRYTCTARN 89 Query: 568 VAG 570 G Sbjct: 90 AFG 92 Score = 39.1 bits (87), Expect = 0.086 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 5/84 (5%) Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216 NI L D C V V P I W NGQ M + V++ G ++L+ + Sbjct: 23 NITALTD-TLVTLHCPVTGVPAPT--ITWSRNGQEMPANGDGYLVTNNGSLILE--KVSS 77 Query: 3217 HDSGEYVCRAYNKYGEDFTRATIN 3240 D G Y C A N +G+D +T+N Sbjct: 78 SDIGRYTCTARNAFGKDNANSTVN 101 Score = 39.1 bits (87), Expect = 0.086 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 2/57 (3%) Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345 ++G P P +TW +NGQ + + ++T N+ +L + SD G YT A N G Sbjct: 38 VTGVPAPTITWSRNGQEMPANGDGYLVT--NNGSLILEKVSSSDIGRYTCTARNAFG 92 Score = 38.7 bits (86), Expect = 0.11 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 6/59 (10%) Query: 97 GNPTPVVSWTRKKAPL-VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154 G P P ++W+R + + Y + T + SL+++++ D G YTCTARN +G+ Sbjct: 40 GVPAPTITWSRNGQEMPANGDGYLV-----TNNGSLILEKVSSSDIGRYTCTARNAFGK 93 Score = 37.5 bits (83), Expect = 0.26 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 2/62 (3%) Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKAT 3918 P I W RNG+ +P+ V + G SL + V + D G Y C A N FG+D +T Sbjct: 42 PAPTITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGKDNANST 99 Query: 3919 IS 3920 ++ Sbjct: 100 VN 101 Score = 37.1 bits (82), Expect = 0.35 Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 2/73 (2%) Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581 N+ + LV L VTG + W +NG+++ + ++ +G +L++ + D Sbjct: 23 NITALTDTLVTLHCPVTGVPAPTITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDI 80 Query: 4582 GKYECVAINSAGE 4594 G+Y C A N+ G+ Sbjct: 81 GRYTCTARNAFGK 93 Score = 37.1 bits (82), Expect = 0.35 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 2/58 (3%) Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801 +T PTI W R G +P D ++ NN L++ D G +TC A A G+ Sbjct: 38 VTGVPAPTITWSRNGQEMPANGDGYLVT--NNGSLILEKVSSSDIGRYTCTARNAFGK 93 Score = 35.5 bits (78), Expect = 1.1 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 4/85 (4%) Query: 3701 IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYI 3760 I DNI V C V V PT I W NG+ + + + G +L ++ + Sbjct: 20 IGDNITALTDTLVTLHCPVTGVPAPT--ITWSRNGQEMPANGDGYLVTNNG--SLILEKV 75 Query: 3761 YARDAGEYTCRATNKWGSATTTAKI 3785 + D G YTC A N +G + + Sbjct: 76 SSSDIGRYTCTARNAFGKDNANSTV 100 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 2/65 (3%) Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723 G P I W +NGQ + A+ + G + L+ +S + D G YTC A +A G Sbjct: 40 GVPAPTITWSRNGQEMPANGDGYLVTNNGSLILEKVSSS--DIGRYTCTARNAFGKDNAN 97 Query: 724 AVLHV 728 + ++V Sbjct: 98 STVNV 102 Score = 33.5 bits (73), Expect = 4.3 Identities = 16/60 (26%), Positives = 32/60 (53%), Gaps = 2/60 (3%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 + W ++G+ + A+ N G +L ++ V+ D G YTC A NA G+ ++ + ++ Sbjct: 46 ITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGKDNANSTVNVM 103 Score = 33.1 bits (72), Expect = 5.7 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797 G P + W RNG + A+ + + G +L ++ V+ D G YTC A N G+ + Sbjct: 40 GVPAPTITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGKDNAN 97 Query: 1798 STLFV 1802 ST+ V Sbjct: 98 STVNV 102 >SB_19559| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 771 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 9/120 (7%) Query: 230 LLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL 289 LL+++ + K+ V ++ +E L P PP I ++P + +QEG + + Sbjct: 100 LLQDMRTKCRTVKQLVSYLELMEHSEALELLKPDEPPVITEQPMSLPVQEGLKLELTCRA 159 Query: 290 SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349 +G P P+ W KNG L +TL + + D G Y + N G + T Sbjct: 160 TGFPPPQYQWVKNGAEL---------PYGCDSTLTIDRVSRQDQGKYFCIISNRIGSVKT 210 Score = 44.0 bits (99), Expect = 0.003 Identities = 22/63 (34%), Positives = 30/63 (47%) Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159 + +E K PPV P ++ V+EG CR TG P P+ W+ NG + G L Sbjct: 125 EALELLKPDEPPVITEQPMSLPVQEGLKLELTCRATGFPPPQYQWVKNGAELPYGCDSTL 184 Query: 4160 TYD 4162 T D Sbjct: 185 TID 187 Score = 41.1 bits (92), Expect = 0.021 Identities = 34/138 (24%), Positives = 56/138 (40%), Gaps = 17/138 (12%) Query: 357 SPTESYVQDQRS------QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410 SPTE +QD R+ Q ++ + E E +E+ + P + V EG Sbjct: 95 SPTECLLQDMRTKCRTVKQLVSYLELMEHSEALELLKPDEPPVITEQPMSLPVQEGLKLE 154 Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470 CR TG P P+ W N ++ Y + L I V+ D G C+ N+ Sbjct: 155 LTCRATGFPPPQYQWVKNGAEL--PY--------GCDSTLTIDRVSRQDQGKYFCIISNR 204 Query: 471 SGET-AFQCRLNVIEKEQ 487 G ++ +NV+ ++ Sbjct: 205 IGSVKTYEVEVNVLRVQR 222 Score = 40.7 bits (91), Expect = 0.028 Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 13/148 (8%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 PP T ++ V G + L + TG P W+KNG + L TL Sbjct: 135 PPVITEQPMSLPVQEGLKLELTCRATGFPPPQYQWVKNGAE---------LPYGCDSTLT 185 Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT--KAANAPPEIIEPLK 4630 I QD GKY C+ N G + V L + + + +T +++ P I + + Sbjct: 186 IDRVSRQDQGKYFCIISNRIGSVKTYEVEVNVLRVQRHEQEEETPLPESSSLPYITQQPQ 245 Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 ++ G +C G P+ QW+K Sbjct: 246 SALIPIGHRYHLTCGTKG-PV-KFQWFK 271 Score = 40.7 bits (91), Expect = 0.028 Identities = 30/84 (35%), Positives = 36/84 (42%), Gaps = 9/84 (10%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550 P E+ +L V+EG + L RA G P P+ W K+G EL D STL I Sbjct: 136 PVITEQPMSLPVQEGLKLELTCRATGFPPPQYQWVKNGA------ELPYGCD---STLTI 186 Query: 551 PRAKASDAAWYQCTAQNVAGSTAT 574 R D Y C N GS T Sbjct: 187 DRVSRQDQGKYFCIISNRIGSVKT 210 Score = 40.3 bits (90), Expect = 0.037 Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 9/120 (7%) Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644 EC+ + + R + V L + + + PP I E V EG +E +C Sbjct: 98 ECLLQDMRTKCRTVKQLVSYLELMEHSEALELLKPDEPPVITEQPMSLPVQEGLKLELTC 157 Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704 + G P P QW K ++ D TL I +D+G Y C+ N G V Sbjct: 158 RATGFPPPQYQWVKNGA--------ELPYGCDS-TLTIDRVSRQDQGKYFCIISNRIGSV 208 Score = 35.1 bits (77), Expect = 1.4 Identities = 37/156 (23%), Positives = 61/156 (39%), Gaps = 21/156 (13%) Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464 +KP +PP+ T++ V E + G P P +W +KN + + Sbjct: 130 LKPDEPPVITEQPMSLPVQEGLKLELTCRATGFPPPQYQW------VKNGAEL---PYGC 180 Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAK---CSANLVVEEKRRQGRGGIVP-----PSF 4516 S L I +V +D + + NR G+ K N++ ++ Q +P P Sbjct: 181 DSTLTIDRVSRQDQGKYFCIISNRIGSVKTYEVEVNVLRVQRHEQEEETPLPESSSLPYI 240 Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLKNG 4551 T Q+ + G L GTK P+ W K+G Sbjct: 241 TQQPQSALIPIGHRYHL---TCGTKGPVKFQWFKDG 273 Score = 34.7 bits (76), Expect = 1.9 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 11/91 (12%) Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750 KP+ P E ++ V EG + CR G P + W NG G Sbjct: 131 KPDEPPVITEQPMSLPVQEGLKLELTCRA--TGFPPPQYQWVKNGAELPYGCDS------ 182 Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATT 3781 L ID + +D G+Y C +N+ GS T Sbjct: 183 ---TLTIDRVSRQDQGKYFCIISNRIGSVKT 210 Score = 32.7 bits (71), Expect = 7.5 Identities = 35/155 (22%), Positives = 60/155 (38%), Gaps = 16/155 (10%) Query: 1114 GVYTVVARNAAGEAQLSA-SMTVETRSSIDTSSIHRGLYEKTRHIEES-KFVEPMYQIEE 1171 G+ +V+ + + Q+S + T + + + K R +++ ++E M E Sbjct: 67 GLISVMPEGSYSQLQVSQFGLAAMRMGGSPTECLLQDMRTKCRTVKQLVSYLELMEHSEA 126 Query: 1172 ISKSKPVFVQPLSNPP---PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228 + KP ++ P PV EG + L CR G P + +W NG + G Sbjct: 127 LELLKPDEPPVITEQPMSLPVQEGLKLELTCR--ATGFPPPQYQWVKNGAELPYGCD--- 181 Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHT 1263 L I + D G+Y N +GS T Sbjct: 182 ------STLTIDRVSRQDQGKYFCIISNRIGSVKT 210 Score = 32.3 bits (70), Expect = 9.9 Identities = 50/225 (22%), Positives = 88/225 (39%), Gaps = 25/225 (11%) Query: 1735 IPVGDPKLRVEWLRNG----VPIEASNRLTTMHDFGYV-ALNMK-YVNPEDSGTYTCRAI 1788 +PV PK + N +P ++L+ M D Y LN + ++ G+Y+ + Sbjct: 23 VPVMAPKYDKQKYYNAQIRELPYSIIHKLSAMLDDPYNRTLNWQGLISVMPEGSYSQLQV 82 Query: 1789 NELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFIT 1848 ++ G A + ++ + Q + LE + E +E+ P IT Sbjct: 83 SQFGLAAMRMGGSPTECLLQDMRTKCRTVKQLVSYLE---LMEHSEALELLKPDEPPVIT 139 Query: 1849 QLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILT 1908 + + EG CR +P P + +W NG L G + L I Sbjct: 140 EQPMSLPVQEGLKLELTCRATGFPPP--QYQWVKNGAELPYGCD---------STLTIDR 188 Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953 V +D G+Y C N +G +V + + V +++R +HE E Sbjct: 189 VSRQDQGKYFCIISNRIG-SVKTYEVEV----NVLRVQRHEQEEE 228 >SB_16914| Best HMM Match : I-set (HMM E-Value=2.3e-10) Length = 94 Score = 44.4 bits (100), Expect = 0.002 Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 11/86 (12%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550 P + VR GE + L G PTP ++W K G H+ GG + Sbjct: 2 PPEITPIQNTTVRAGETITLTCAVAGYPTPSVSWSKAGSG---------HSTGG-NVFTK 51 Query: 551 PRAKASDAAWYQCTAQN-VAGSTATR 575 P A D Y CTA N V+G+T TR Sbjct: 52 PGATKEDTGQYVCTAVNTVSGNTQTR 77 Score = 37.1 bits (82), Expect = 0.35 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 11/79 (13%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 PPEI P+++ V G+ I +C + G P P+V W K S + +T Sbjct: 2 PPEIT-PIQNTTVRAGETITLTCAVAGYPTPSVSWSKAGS--------GHSTGGNVFTK- 51 Query: 4682 ISEAFPEDEGDYKCVAYNS 4700 A ED G Y C A N+ Sbjct: 52 -PGATKEDTGQYVCTAVNT 69 >SB_13005| Best HMM Match : PSI (HMM E-Value=2.9e-11) Length = 829 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/98 (30%), Positives = 41/98 (41%), Gaps = 5/98 (5%) Query: 66 PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTP-VVSWTRKKAPLVECNKYSMRYNE 124 P EP E I +N G E K G P P VV+W + L KY ++ Sbjct: 399 PSEPPSCAIEVIKENP----GQETILECKAEGIPVPEVVAWEKDSVKLAYDGKYRIQKTG 454 Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162 G L I G G YTC ++ G+A CS+ ++ Sbjct: 455 SQGSQRLSISPFGVKHLGTYTCQVQSTMGKADCSLEVK 492 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 7/91 (7%) Query: 2117 SLENLKE--GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT--THDFGYVALDIL 2172 ++E +KE G EC+ E I P + + W + K+ +YR T G L I Sbjct: 406 AIEVIKENPGQETILECKAEGIPVPEV-VAWEKDSVKLAYDGKYRIQKTGSQGSQRLSIS 464 Query: 2173 YTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203 + GTY C+ + +G+A C+L+V G Sbjct: 465 PFGVKHLGTYTCQVQSTMGKA--DCSLEVKG 493 Score = 34.3 bits (75), Expect = 2.5 Identities = 36/144 (25%), Positives = 56/144 (38%), Gaps = 15/144 (10%) Query: 406 GKMTRFDCRVTGRPYPE-VTWFINDRQIRDDYNHKI-LVNESGNHALMITNVTLSDSGVV 463 G+ T +C+ G P PE V W + ++ D ++I G+ L I+ + G Sbjct: 415 GQETILECKAEGIPVPEVVAWEKDSVKLAYDGKYRIQKTGSQGSQRLSISPFGVKHLGTY 474 Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523 TC ++ G+ C L V V F + + A GTP P I+ Sbjct: 475 TCQVQSTMGKA--DCSLEVKGSLPAVTSGF--------TKHALKTYFSCTAKGTPLPSIS 524 Query: 524 WQK--DGV-PIIPNPELRIHTDGG 544 K GV ++P + I D G Sbjct: 525 MYKVSGGVSQLLPGNNVSIEQDMG 548 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 3/79 (3%) Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA--RLKSTFDFGLVTLSINSLRNDDSGI 2714 GQ LE + E P + + W K+ V L R++ T G LSI+ G Sbjct: 415 GQETILECKAEGIPVPEV-VAWEKDSVKLAYDGKYRIQKTGSQGSQRLSISPFGVKHLGT 473 Query: 2715 YTCKATNLLGEAVSTASIK 2733 YTC+ + +G+A + +K Sbjct: 474 YTCQVQSTMGKADCSLEVK 492 Score = 33.1 bits (72), Expect = 5.7 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 5/98 (5%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLKNGKKVQPDIRNKILE--EDGTY 4569 PPS + N GQ L+ K G P V W K+ K+ D + +I + G+ Sbjct: 402 PPSCAIEVIKEN--PGQETILECKAEGIPVPEVVAWEKDSVKLAYDGKYRIQKTGSQGSQ 459 Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607 L I + G Y C ++ G+A C E SLPA Sbjct: 460 RLSISPFGVKHLGTYTCQVQSTMGKADCSLEVKGSLPA 497 Score = 32.7 bits (71), Expect = 7.5 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 7/98 (7%) Query: 4622 PPEI-IEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGD-KLIKPSKY-FQMSRTADE 4677 PP IE +K+ GQ CK G P+P V W K KL KY Q + + Sbjct: 402 PPSCAIEVIKEN---PGQETILECKAEGIPVPEVVAWEKDSVKLAYDGKYRIQKTGSQGS 458 Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715 L IS + G Y C ++ G+ + ++K + P Sbjct: 459 QRLSISPFGVKHLGTYTCQVQSTMGKADCSLEVKGSLP 496 >SB_43138| Best HMM Match : Pox_A_type_inc (HMM E-Value=1.3e-14) Length = 1709 Score = 43.2 bits (97), Expect = 0.005 Identities = 36/155 (23%), Positives = 70/155 (45%), Gaps = 6/155 (3%) Query: 4250 RPELKPKVIKEPETEWQQS-VKRKK-NEEYYNKLQELENEQVIKESRLRESTHQYAIPGD 4307 + EL+ ++ K+ E +++ KR+K EEY KL+ + E V + S+ +E +Q Sbjct: 1210 KEELEEQIAKKREQLAKEAGAKRQKLKEEYEGKLRVIYEELVSERSKNKELMNQNNQLSQ 1269 Query: 4308 KVTS----NTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVA 4363 KV T K +R + ++ +E+ Q Q + T P++ + E + E ++ Sbjct: 1270 KVKLLEGVTTKQKKDIERVKQMEEKLKELERQSKQSEETDNPKVIESYEDKIKALEKEIS 1329 Query: 4364 KQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE 4398 K +E+ K+T E E +T++ Sbjct: 1330 NLKDRNNNGEKVQELLHKVTYLEGELKERSVETEK 1364 >SB_33085| Best HMM Match : Trypsin (HMM E-Value=0) Length = 537 Score = 43.2 bits (97), Expect = 0.005 Identities = 45/163 (27%), Positives = 62/163 (38%), Gaps = 24/163 (14%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 CR TG P PE W N R I H + I +D GV TCVA+N G Sbjct: 118 CRSTGNPIPEFKWTKNGRVIH------------VGHVINIARSFKTDEGVYTCVAQNGRG 165 Query: 473 ET-AFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531 T + ++++ + +V + N A G P P I+W+K P Sbjct: 166 FTNSVSSTVSIVYYSPRIQQPLQNDTFVEDVSRNFRLYCN--ATGNPRPMISWRKREDP- 222 Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574 R +G TL + R + Y CTA N GS + Sbjct: 223 -----GRDFVNGPELTLRMSRDSKGN---YTCTATNDRGSVTS 257 Score = 41.9 bits (94), Expect = 0.012 Identities = 45/183 (24%), Positives = 72/183 (39%), Gaps = 26/183 (14%) Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692 ++ E I +C+ G P+P +W K ++I + + I+ +F DEG Sbjct: 107 VINETDPILLTCRSTGNPIPEFKWTKNGRVIHVG-----------HVINIARSFKTDEGV 155 Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK--TQITSKIKP 4750 Y CVA N G T + V+ + + PL++ E F+ T +P Sbjct: 156 YTCVAQNGRG-FTNSVSSTVSIVYYSPRIQ--QPLQNDTFVEDVSRNFRLYCNATGNPRP 212 Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 I W + E P ++ G L + + G +TC AT G V TS V+ Sbjct: 213 MISWRKR-----EDPGRDFVN-GPELTLRMS---RDSKGNYTCTATNDRGSV-TSIVGVI 262 Query: 4811 KSK 4813 K Sbjct: 263 DMK 265 Score = 38.7 bits (86), Expect = 0.11 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 12/105 (11%) Query: 469 NKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEPVVLNARAVGTPTPRITWQKD 527 +K+ A L V KE ++P ++L + E +P++L R+ G P P W K+ Sbjct: 74 SKAKSLAHNDLLPVYRKELRLSPHNTTATPASLVINETDPILLTCRSTGNPIPEFKWTKN 133 Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572 G IH ++I R+ +D Y C AQN G T Sbjct: 134 G--------RVIHV---GHVINIARSFKTDEGVYTCVAQNGRGFT 167 Score = 33.1 bits (72), Expect = 5.7 Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 13/84 (15%) Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615 +P T TP+ L+++E CR + +W NG+ + G Sbjct: 95 SPHNTTATPASLVINETDPILLTCR--STGNPIPEFKWTKNGRVIHVGH----------- 141 Query: 3616 ILEIGGVYQRDAGLYTCKATNRHG 3639 ++ I ++ D G+YTC A N G Sbjct: 142 VINIARSFKTDEGVYTCVAQNGRG 165 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322 +SP P + + E + +GNP P W KNG R+I H Sbjct: 94 LSPHNTTATPASLVINETDPILLTCRSTGNPIPEFKWTKNG-RVI----------HVGHV 142 Query: 323 LRVRNTQKSDSGHYTLLAENPNG 345 + + + K+D G YT +A+N G Sbjct: 143 INIARSFKTDEGVYTCVAQNGRG 165 >SB_35648| Best HMM Match : I-set (HMM E-Value=8.5e-05) Length = 181 Score = 43.2 bits (97), Expect = 0.005 Identities = 45/174 (25%), Positives = 76/174 (43%), Gaps = 23/174 (13%) Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591 +L +V G P +V W +G + + ++ + DG+ L+I+ +DSG+Y+ + N+ Sbjct: 22 KLQLRVFGFPPPNVTW--SGPALSHS-KPRVNQSDGS--LVIMRTEFRDSGEYKAIVKNA 76 Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651 GE VVS KP A P + + + + +C +G P Sbjct: 77 VGEVVVRTFLVVSQGV-----KPMFYATPDRPWLA-------IERSKTLPLTCGAMGVPS 124 Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705 P V+WY IK + T + T+ +S + EG+Y C A N G V+ Sbjct: 125 PIVEWYHNGSPIKSG----VGGTKNNKTVTLS--WGSLEGNYLCRARNIFGVVS 172 Score = 41.5 bits (93), Expect = 0.016 Identities = 43/163 (26%), Positives = 66/163 (40%), Gaps = 17/163 (10%) Query: 410 RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469 + RV G P P VTW + + + K VN+S +L+I DSG + +N Sbjct: 22 KLQLRVFGFPPPNVTW--SGPALS---HSKPRVNQSDG-SLVIMRTEFRDSGEYKAIVKN 75 Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFST--LNVREGEPVVLNARAVGTPTPRITWQKD 527 GE + L V Q V P F L + + + L A+G P+P + W + Sbjct: 76 AVGEVVVRTFLVV---SQGVKPMFYATPDRPWLAIERSKTLPLTCGAMGVPSPIVEWYHN 132 Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 G PI + G + + + S Y C A+N+ G Sbjct: 133 GSPI------KSGVGGTKNNKTVTLSWGSLEGNYLCRARNIFG 169 Score = 40.7 bits (91), Expect = 0.028 Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 12/125 (9%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF-TTHIQNIEGLKDGQS 3166 L I+ T+ DSG Y N G+ + L S+G KP F T + ++ ++ Sbjct: 56 LVIMRTEFRDSGEYKAIVKNAVGEVVVRTFLVV---SQGVKPMFYATPDRPWLAIERSKT 112 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226 C + V P +EWYHNG P++ + + + V L + G Y+CRA Sbjct: 113 LPLTCGAMGVPSPI--VEWYHNGSPIK--SGVGGTKNNKTVTLSWGSLE----GNYLCRA 164 Query: 3227 YNKYG 3231 N +G Sbjct: 165 RNIFG 169 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/61 (42%), Positives = 29/61 (47%), Gaps = 7/61 (11%) Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670 VEWYHN P+KSG T+ N V L S G Y CRA N G V+ I I Sbjct: 127 VEWYHNGSPIKSGVGGTKNNK--TVTLSWGSL----EGNYLCRARNIFG-VVSKSIFIEQ 179 Query: 1671 S 1671 S Sbjct: 180 S 180 Score = 35.9 bits (79), Expect = 0.80 Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 6/91 (6%) Query: 266 PKIAQKPRNSKL-QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 P+I +P+ + A + Q+++ G P P VTW +G L +S + +L Sbjct: 3 PRIKDQPKAIEFGYHPAAKKLQLRVFGFPPPNVTW--SGPALSHSKPR---VNQSDGSLV 57 Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355 + T+ DSG Y + +N G +V +L V Sbjct: 58 IMRTEFRDSGEYKAIVKNAVGEVVVRTFLVV 88 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030 +P + T + ++ +T C +G P+ VEW+ NG P+ K+ + Sbjct: 93 KPMFYATPDRPWLAIERSKTLPLTC--GAMGVPSPIVEWYHNGSPI--KSGVGGTKNNKT 148 Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGM 4056 V +++G + G YLCRA N++G+ Sbjct: 149 VTLSWGSL----EGNYLCRARNIFGV 170 >SB_23794| Best HMM Match : ig (HMM E-Value=3.1e-07) Length = 175 Score = 42.7 bits (96), Expect = 0.007 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 13/130 (10%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P F +D++ ++N C D + W HNG+ + T S + V+ Sbjct: 6 PAFMDITADIVANKNEDVSLPCT--STGDLPITTTWSHNGQVVQTSSSHSNL-----VLS 58 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL-PSHFKSGTESIQKLE 3676 + G AG Y C TN G + + L+VKG + + Q+ P ++ T+ I +E Sbjct: 59 HVNG---SQAGSYNCTVTNSRGSNSRTTYLRVKGGGSVKVFSQVSPGQGETRTQQIMHIE 115 Query: 3677 ETLHKREEIT 3686 H E T Sbjct: 116 --YHVTSEFT 123 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 8/89 (8%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782 GD + W HNG+ T S H+ L + ++ AG Y C TN GS + T Sbjct: 31 GDLPITTTWSHNGQVVQTSSS-HS-------NLVLSHVNGSQAGSYNCTVTNSRGSNSRT 82 Query: 3783 AKITCSAKRDIVLESQLPQGMSGEKIKEL 3811 + + + SQ+ G + +++ Sbjct: 83 TYLRVKGGGSVKVFSQVSPGQGETRTQQI 111 Score = 32.7 bits (71), Expect = 7.5 Identities = 16/53 (30%), Positives = 28/53 (52%) Query: 2829 SYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGK 2881 S+ +L ++H +G Y C TNS+GS + + LR G ++ +Q G+ Sbjct: 51 SHSNLVLSHVNGSQAGSYNCTVTNSRGSNSRTTYLRVKGGGSVKVFSQVSPGQ 103 >SB_2033| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 995 Score = 42.7 bits (96), Expect = 0.007 Identities = 18/70 (25%), Positives = 35/70 (50%) Query: 268 IAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRN 327 + + P++ +L+ G + G P P W+K+ + + +T + +L + N Sbjct: 161 VLEFPKSQRLERGQSQVIRCSAEGYPTPHYQWYKDWNPTVLDYSDDRLTLLPNGSLLISN 220 Query: 328 TQKSDSGHYT 337 Q+SDSG+YT Sbjct: 221 VQESDSGNYT 230 Score = 37.9 bits (84), Expect = 0.20 Identities = 40/175 (22%), Positives = 73/175 (41%), Gaps = 18/175 (10%) Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121 + Q+ A PT +W N ++ S T+ G +++ + +DSG Y Sbjct: 174 QSQVIRCSAEGYPTPHYQWYKDW--NPTVLDYSDDRLTLLPNGSLLIS--NVQESDSGNY 229 Query: 3122 SCRATN-----KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176 +CR T + + + ++++ + R +T + + G G FECT Sbjct: 230 TCRITQLDEVGRPREEQKNIEVLVYGPPRVDLSRSSTVVYSYIGNLRGDK--FECTFWGY 287 Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231 P M + H + +T++K + G V + T + D G+Y CRA N+ G Sbjct: 288 PIPKMSM---HRSGAVLKNTKVKDRTITGHVTV----TSDEDFGDYECRASNELG 335 Score = 37.1 bits (82), Expect = 0.35 Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 19/159 (11%) Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSST--LFVQSKASLQLESQHESALQ-KIQQLED 1826 L +K + +D G Y C+ A TS LFV+ SL+ + +HE+ ++ I+ + Sbjct: 85 LVIKSIEVKDGGYYKCKG------AKTSKLFHLFVECFQSLR-DVRHENGIKDNIKSVHK 137 Query: 1827 SSRYQRREDVEVA-VNQAPRFITQLNGPT--KLSEGQSAHYECRIEPYPDPNMRVEWY-- 1881 + + + + + +++ + L P +L GQS C E YP P+ +WY Sbjct: 138 HNLHLALKRIHKSNLSKLFHAVVVLEFPKSQRLERGQSQVIRCSAEGYPTPH--YQWYKD 195 Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920 +N VL T G +L I V DSG YTC+ Sbjct: 196 WNPTVLDYSDDRLTLLPNG--SLLISNVQESDSGNYTCR 232 Score = 34.7 bits (76), Expect = 1.9 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 11/128 (8%) Query: 1811 ESQHESALQKIQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLS---EGQSAHYEC 1866 ES + +I QL++ R + ++++EV V PR + S + +EC Sbjct: 223 ESDSGNYTCRITQLDEVGRPREEQKNIEVLVYGPPRVDLSRSSTVVYSYIGNLRGDKFEC 282 Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926 YP P M + + +G VL++ + + G + ED G+Y C+A N LG Sbjct: 283 TFWGYPIPKMSM--HRSGAVLKNT-KVKDRTITGH----VTVTSDEDFGDYECRASNELG 335 Query: 1927 QAVSSIRL 1934 A ++L Sbjct: 336 NATHIVQL 343 Score = 33.5 bits (73), Expect = 4.3 Identities = 15/33 (45%), Positives = 20/33 (60%) Query: 2171 ILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203 + T ED G Y C+A+N+LG A + LK AG Sbjct: 315 VTVTSDEDFGDYECRASNELGNATHIVQLKQAG 347 Score = 33.1 bits (72), Expect = 5.7 Identities = 42/181 (23%), Positives = 65/181 (35%), Gaps = 11/181 (6%) Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684 ++E K + + GQ+ C G P P QWYK +L IS Sbjct: 161 VLEFPKSQRLERGQSQVIRCSAEGYPTPHYQWYKDWNPTVLDYSDDRLTLLPNGSLLISN 220 Query: 4685 AFPEDEGDYKC--VAYNSAGRVTVAAK---LKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739 D G+Y C + GR K + V P + D + T + + + + Sbjct: 221 VQESDSGNYTCRITQLDEVGRPREEQKNIEVLVYGPPRVDLSRSSTVVYS-YIGNLRGDK 279 Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799 F+ P + R GA++ T G+ V T +ED G + CRA+ Sbjct: 280 FECTFWGYPIPKMSMHRSGAVLKNTKVKDRTITGHVTV-----TSDEDFGDYECRASNEL 334 Query: 4800 G 4800 G Sbjct: 335 G 335 >SB_43971| Best HMM Match : I-set (HMM E-Value=1.7e-09) Length = 240 Score = 42.7 bits (96), Expect = 0.007 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 8/105 (7%) Query: 2630 PEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA 2689 P D ++ AP FT+ L S + E V + R PN + W V T+G+ Sbjct: 140 PSTSWDLNIKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPN--VTW----VNKTSGS 193 Query: 2690 RLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 + G TLS+ ++ +G+Y C+A N +G T I I Sbjct: 194 PV--AHGTGNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDITI 236 Score = 39.9 bits (89), Expect = 0.049 Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 11/125 (8%) Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874 +S L KI+ SS ++ + AP F + L+ ++E C P P Sbjct: 124 KSYLVKIRT-SSSSPLSPSTSWDLNIKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAP 182 Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSI 1932 N V W K S + T N A L +L + +G Y C+AIN++G+ I Sbjct: 183 N--VTWV--NKTSGSPVAHGTGN----ATLSLLKIQRHQAGVYQCQAINDVGRGAITQDI 234 Query: 1933 RLNVQ 1937 +NVQ Sbjct: 235 TINVQ 239 Score = 38.7 bits (86), Expect = 0.11 Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 11/88 (12%) Query: 489 VAPKFVERFSTL-NVREGEPVVLNARAVGTPTPRITW--QKDGVPIIPNPELRIHTDGGA 545 VAP F S+ +V E + V + A G P P +TW + G P+ H G A Sbjct: 150 VAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNVTWVNKTSGSPV-------AHGTGNA 202 Query: 546 STLDIPRAKASDAAWYQCTAQNVAGSTA 573 TL + + + A YQC A N G A Sbjct: 203 -TLSLLKIQRHQAGVYQCQAINDVGRGA 229 Score = 37.9 bits (84), Expect = 0.20 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 8/87 (9%) Query: 390 LAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448 +AP F + RDV E C +GRP P VTW +N + + + +GN Sbjct: 150 VAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNVTW-VNKT------SGSPVAHGTGNA 202 Query: 449 ALMITNVTLSDSGVVTCVARNKSGETA 475 L + + +GV C A N G A Sbjct: 203 TLSLLKIQRHQAGVYQCQAINDVGRGA 229 Score = 35.1 bits (77), Expect = 1.4 Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 12/98 (12%) Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRPFATGSRVHTLNDFGF 3752 P FT + + DV E V C G P + W + +G P A G+ G Sbjct: 152 PAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNVTWVNKTSGSPVAHGT--------GN 201 Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790 L + I AG Y C+A N G T IT + + Sbjct: 202 ATLSLLKIQRHQAGVYQCQAINDVGRGAITQDITINVQ 239 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/132 (21%), Positives = 54/132 (40%), Gaps = 13/132 (9%) Query: 1409 ILESQHPSGLEKIQYL-----EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463 ++E ++ S +++ YL +S + D ++ + P F + S +V E V Sbjct: 112 VVEIRNASAVDEKSYLVKIRTSSSSPLSPSTSWDLNIKVAPAFTSSLSSSRDVAENDDVT 171 Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523 C N+ +G PV H G L ++ + +G+Y C+A+N Sbjct: 172 VTCSASGRPAPNVTWVNKTSGSPVA--------HGTGNATLSLLKIQRHQAGVYQCQAIN 223 Query: 1524 LVGTDEVSCRLT 1535 VG ++ +T Sbjct: 224 DVGRGAITQDIT 235 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/127 (22%), Positives = 49/127 (38%), Gaps = 9/127 (7%) Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKS-HTVEES 3844 +CS +I S + + KI+ +S + + + P F + + S V E+ Sbjct: 108 SCSGVVEIRNASAVDEKSYLVKIRTSSSSPLSPSTSWDLNIKVAPAFTSSLSSSRDVAEN 167 Query: 3845 EGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYIC 3904 + V C + P + W P H G +L +L + +G Y C Sbjct: 168 DDVTVTCSASGRPAPN--VTWVNKTSGSPVAH------GTGNATLSLLKIQRHQAGVYQC 219 Query: 3905 RAVNDFG 3911 +A+ND G Sbjct: 220 QAINDVG 226 Score = 32.7 bits (71), Expect = 7.5 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 14/97 (14%) Query: 1304 DITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGDQTMRVEWF--CNGKPIKTGHRFR 1360 D+ + AP F+ +L + V E +V + C G V W +G P+ Sbjct: 145 DLNIKVAPAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNVTWVNKTSGSPV------- 195 Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE-AVT 1396 A+ L LL + +GVY CQA N +G A+T Sbjct: 196 -AHGTGNATLSLLKIQRHQAGVYQCQAINDVGRGAIT 231 Score = 32.7 bits (71), Expect = 7.5 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 15/102 (14%) Query: 1707 ITQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR--NGVPIEASNRLTTMH 1763 I AP FT + R VAEN G P V W+ +G P+ H Sbjct: 148 IKVAPAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNVTWVNKTSGSPVA--------H 197 Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQ 1803 G L++ + +G Y C+AIN++G A+T T+ VQ Sbjct: 198 GTGNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDITINVQ 239 >SB_29801| Best HMM Match : Collagen (HMM E-Value=3.2e-12) Length = 182 Score = 42.3 bits (95), Expect = 0.009 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 4/76 (5%) Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549 AP+ + LN+ VVLN G P+ +TW K G +P R D G L Sbjct: 94 APRVIIAPQKLNIDSSATVVLNCSVSGNPSAPVTWSKIG-GSLPRNRSR---DDGRGGLV 149 Query: 550 IPRAKASDAAWYQCTA 565 I A++SDA Y+C + Sbjct: 150 IRDARSSDAGLYECAS 165 Score = 41.1 bits (92), Expect = 0.021 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 4/83 (4%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 P + Q +N+ S V L+ V+G V W K G + RN+ +DG L+I Sbjct: 95 PRVIIAPQKLNIDSSATVVLNCSVSGNPSAPVTWSKIGGSLP---RNRS-RDDGRGGLVI 150 Query: 4574 LEAYPQDSGKYECVAINSAGEAR 4596 +A D+G YEC ++ ++R Sbjct: 151 RDARSSDAGLYECASVGGLYKSR 173 Score = 33.1 bits (72), Expect = 5.7 Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 4/71 (5%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325 P++ P+ + A +SGNP VTW K G L + + L + Sbjct: 95 PRVIIAPQKLNIDSSATVVLNCSVSGNPSAPVTWSKIGGSLPRNRSRD----DGRGGLVI 150 Query: 326 RNTQKSDSGHY 336 R+ + SD+G Y Sbjct: 151 RDARSSDAGLY 161 >SB_3251| Best HMM Match : I-set (HMM E-Value=1.8e-07) Length = 147 Score = 42.3 bits (95), Expect = 0.009 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 13/123 (10%) Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 D G Y C NS G+ +SL + + + PE P ++ G Sbjct: 16 DEGHYICRVANSNGDYVFTEWAKLSLQNPSETHQFSRPIITSQPEY--PEVHTVL--GGT 71 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 + C +G P PT QWYK D L P EY R + +D+G Y CVA N Sbjct: 72 LRLYCDALGDPAPTFQWYKND-LPLP------DGDQREYCKR--DICADDQGRYMCVASN 122 Query: 4700 SAG 4702 S+G Sbjct: 123 SSG 125 Score = 37.9 bits (84), Expect = 0.20 Identities = 41/154 (26%), Positives = 61/154 (39%), Gaps = 35/154 (22%) Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGY--LAVESPTESYVQDQRSQYITDTQQRETE 380 LRV+N K D GHY N NG V + + L++++P+E++ Q S+ I +Q Sbjct: 7 LRVKNVSKLDEGHYICRVANSNGDYVFTEWAKLSLQNPSETH---QFSRPIITSQ----- 58 Query: 381 ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440 P++ +V G R C G P P W+ ND + D + Sbjct: 59 -----------PEYPEV----HTVLGGTLRLYCDALGDPAPTFQWYKNDLPLPDGDQREY 103 Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGET 474 + + D G CVA N SG T Sbjct: 104 CKRD----------ICADDQGRYMCVASNSSGST 127 Score = 37.5 bits (83), Expect = 0.26 Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 16/133 (12%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQ--CRL---NVIEKEQVVAPKFVER--FSTLNV 502 L + NV+ D G C N +G+ F +L N E Q P + + ++ Sbjct: 7 LRVKNVSKLDEGHYICRVANSNGDYVFTEWAKLSLQNPSETHQFSRPIITSQPEYPEVHT 66 Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562 G + L A+G P P W K+ +P+ P+ + R + DI A D Y Sbjct: 67 VLGGTLRLYCDALGDPAPTFQWYKNDLPL-PDGDQREYCKR-----DIC---ADDQGRYM 117 Query: 563 CTAQNVAGSTATR 575 C A N +GST +R Sbjct: 118 CVASNSSGSTESR 130 Score = 35.1 bits (77), Expect = 1.4 Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 16/90 (17%) Query: 1976 EKPQFGKPI--KNAEVTEGHPVHLEATLT----PVNDPTMRVEWYCNGRPVQQGHRFKTT 2029 E QF +PI E E H V L TL + DP +WY N P+ G + + Sbjct: 46 ETHQFSRPIITSQPEYPEVHTV-LGGTLRLYCDALGDPAPTFQWYKNDLPLPDGDQRE-- 102 Query: 2030 YDFGYVALDILYAYAEDTGTYMCKATNAVG 2059 Y DI A+D G YMC A+N+ G Sbjct: 103 ----YCKRDIC---ADDQGRYMCVASNSSG 125 Score = 35.1 bits (77), Expect = 1.4 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 22/113 (19%) Query: 3824 PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883 PI+++ P++ + HTV +R C + DP +WY+N LP G + Sbjct: 53 PIITSQPEYP---EVHTVLGGT-LRLYC--DALGDPAPTFQWYKNDLPLPDGDQRE---- 102 Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRG 3936 + DI A+D G Y+C A N G ++ T + +++QVPRG Sbjct: 103 --YCKRDIC---ADDQGRYMCVASNSSGSTESRPT-------RVFVRHQVPRG 143 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 9/55 (16%) Query: 2802 DPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGS 2856 DP +W+ N+ PLP G + + Y DI +D G Y C A+NS GS Sbjct: 81 DPAPTFQWYKNDLPLPDGDQRE------YCKRDIC---ADDQGRYMCVASNSSGS 126 >SB_56336| Best HMM Match : Ag332 (HMM E-Value=5.1) Length = 366 Score = 41.9 bits (94), Expect = 0.012 Identities = 55/227 (24%), Positives = 96/227 (42%), Gaps = 21/227 (9%) Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNE 4275 P +E Q + E E ++ ++ +++G ++ P+L+ V +EP+ E + K+ E Sbjct: 90 PVEEEPKQEEPVEEEQKQEEPVKEEPKQEGQVEEEPKLEEPVEEEPKQEEPVEEEPKQEE 149 Query: 4276 EYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK-SMAQRYEDNLDQTEEVTE 4334 + E + E V +ES++ AI TS K Q E+ Q E V E Sbjct: 150 PF-----EEQKEAVAEESKVDAPV---AID----TSGVYEKPKQEQPVEEKSKQEEPVEE 197 Query: 4335 QRVQKK-VTQKPRIPDPSESTVHGKEV--HVAKQKQTQKEVVGDKEITRKITSTETTEIE 4391 + QK+ V ++P+ S +E+ KQ+ +E +E K E E+ Sbjct: 198 EPKQKELVGEEPKTRRTSRRRTKQEEIVEEEPKQEGPVEEETRQEEPDEK--EREQEELV 255 Query: 4392 HKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438 + +E VE K +P K + E+ + E + DGEP Sbjct: 256 EEEPKKEEPVEEETKQEEPVEEEPKQEEA---VDEEPKKEEQVDGEP 299 >SB_49916| Best HMM Match : ig (HMM E-Value=8.5e-06) Length = 465 Score = 41.9 bits (94), Expect = 0.012 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 11/79 (13%) Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559 + ++EG+ + L+ A GTP P++TW+K+G+ I+ N I+T I Sbjct: 14 IKLKEGDSISLDCTASGTPAPKVTWRKNGL-ILSNQS--IYT--------ITITTRYQYG 62 Query: 560 WYQCTAQNVAGSTATRARL 578 Y C A N+AG TA + ++ Sbjct: 63 NYTCEASNIAGKTAWQGQI 81 Score = 39.9 bits (89), Expect = 0.049 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 266 PKIAQKPRNS--KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317 PK+ + P + KL+EG SG P P+VTW KNG L N + + I T Sbjct: 3 PKLNKSPPDKIIKLKEGDSISLDCTASGTPAPKVTWRKNGLILSNQSIYTITIT 56 Score = 38.3 bits (85), Expect = 0.15 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 19/132 (14%) Query: 391 APQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448 AP+ K D+ + EG DC +G P P+VTW R+ N IL N+S Sbjct: 2 APKLNKSPPDKIIKLKEGDSISLDCTASGTPAPKVTW----RK-----NGLILSNQS--- 49 Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508 IT T G TC A N +G+TA+Q ++ + QV + V +T++ Sbjct: 50 IYTITITTRYQYGNYTCEASNIAGKTAWQGQI----QSQVFPEENVTTITTVSPPSAGST 105 Query: 509 VLNARAVGTPTP 520 V + R V P P Sbjct: 106 V-STRQVKQPPP 116 Score = 37.1 bits (82), Expect = 0.35 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Query: 4110 PPVFVSLPDAVT-VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF 4167 P + S PD + ++EG+ C +G P P+V W NG + N S Y +T Y + Sbjct: 3 PKLNKSPPDKIIKLKEGDSISLDCTASGTPAPKVTWRKNGLILSNQSIYTITITTRYQY 61 Score = 35.5 bits (78), Expect = 1.1 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 14/105 (13%) Query: 4623 PEIIEPLKDKIVA--EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680 P++ + DKI+ EG +I C G P P V W K ++ YT+ Sbjct: 3 PKLNKSPPDKIIKLKEGDSISLDCTASGTPAPKVTWRKNGLILSNQSI---------YTI 53 Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725 I+ + G+Y C A N AG+ +++ +Q +N+ +T Sbjct: 54 TITTRY--QYGNYTCEASNIAGKTAWQGQIQ-SQVFPEENVTTIT 95 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 13/82 (15%) Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842 I KEGD+I +C S P K+ W N L + + Y T IT Y+ Sbjct: 14 IKLKEGDSISLDCTA--SGTPAPKVTWRKNGLILSNQSIYTIT---------ITTRYQY- 61 Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864 G YTC+A+N G G ++ Sbjct: 62 -GNYTCEASNIAGKTAWQGQIQ 82 Score = 32.7 bits (71), Expect = 7.5 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 11/72 (15%) Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582 + + G + LD +GT V W KNG IL YT+ I Y G Sbjct: 14 IKLKEGDSISLDCTASGTPAPKVTWRKNG---------LILSNQSIYTITITTRY--QYG 62 Query: 4583 KYECVAINSAGE 4594 Y C A N AG+ Sbjct: 63 NYTCEASNIAGK 74 >SB_25723| Best HMM Match : Vicilin_N (HMM E-Value=0.0045) Length = 2506 Score = 41.9 bits (94), Expect = 0.012 Identities = 31/170 (18%), Positives = 81/170 (47%), Gaps = 3/170 (1%) Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDN 4325 +Q K+ E++ ++++ ++EQV + + RE Q I ++++ + + +R ED Sbjct: 140 KQESDLKRREQWQKEMKQKKDEQVDEREKQREKQRQEKIMREQMSRKIKLRIVQKRSED- 198 Query: 4326 LDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITST 4385 D+ +E + +KK +K R + + +A ++ Q + + E R+ Sbjct: 199 -DKRQESNHNK-RKKSMKKIREEKMKDQWKRRCSISLAHLERKQMKEMQRLERRRQNIER 256 Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFD 4435 T+ ++ ++ Q+ V+E +K + ++ + ++ +H + + E E + Sbjct: 257 RTSTVQEHSEKQQAVLEQCLKTRRNTLYQEFLKAEEFMQHLREKKERELN 306 >SB_43939| Best HMM Match : I-set (HMM E-Value=1.3e-14) Length = 84 Score = 41.5 bits (93), Expect = 0.016 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 11/91 (12%) Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLR 4681 P+II+P D+ + EG+ + SC G P+P V W + G +L S ++S Sbjct: 3 PKIIQPPTDRTLNEGETLILSCYPGGFPVPYVTWRFNGTRLAANSSVLEIS--------D 54 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 + A G Y CVA N AG T A + + Sbjct: 55 VKRAM--HHGTYTCVATNLAGSDTADAFITI 83 Score = 39.1 bits (87), Expect = 0.086 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 11/87 (12%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550 PK ++ + + EGE ++L+ G P P +TW+ +G + N +S L+I Sbjct: 3 PKIIQPPTDRTLNEGETLILSCYPGGFPVPYVTWRFNGTRLAAN----------SSVLEI 52 Query: 551 PRAK-ASDAAWYQCTAQNVAGSTATRA 576 K A Y C A N+AGS A Sbjct: 53 SDVKRAMHHGTYTCVATNLAGSDTADA 79 Score = 35.1 bits (77), Expect = 1.4 Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEI 314 PKI Q P + L EG G P P VTW NG RL NS+ EI Sbjct: 3 PKIIQPPTDRTLNEGETLILSCYPGGFPVPYVTWRFNGTRLAANSSVLEI 52 >SB_1939| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1646 Score = 41.5 bits (93), Expect = 0.016 Identities = 36/175 (20%), Positives = 80/175 (45%), Gaps = 10/175 (5%) Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYY 4278 ++ Q ++ E E +K EE ++ + R + + K+ + + ++ +R++ +E Sbjct: 155 EKEKQRKQLEVEKQKRLEEERIRSQNEERKRREREQKEREKQQKLDMEKEERRRRQQEEE 214 Query: 4279 NKLQELENEQ--VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQR 4336 K +E E ++ V KE + RE + I + T Q+Y + + +++ Sbjct: 215 KKRREEEEKRKKVEKEKQEREKAAKKNIKRQQQQQRTDQ----QQYPREIPPRFQKMKRQ 270 Query: 4337 VQKKVTQKPRIPDPSESTVHGKEVHVAK-QKQTQKEVVGDKEITRKITSTETTEI 4390 Q++ Q P +P P+ + G + K Q + Q++ VG K+ + S E ++ Sbjct: 271 QQQQQLQTPNLPPPAPT---GSPAQLNKFQSKPQQQPVGKKKDPNRFASKEYADL 322 Score = 33.5 bits (73), Expect = 4.3 Identities = 36/187 (19%), Positives = 82/187 (43%), Gaps = 7/187 (3%) Query: 4235 FEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESR 4294 FE++ V + + V + KPK K+ E Q + K+ E+ +L+E E+ KE + Sbjct: 102 FEQQAVKKGKAVSVPVAKPKPKSKKQLLAE--QRRRAKEMEQIAMELEEKRKEEEEKEKQ 159 Query: 4295 LR--ESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSE 4352 + E Q + +++ S + +R + ++ +++ ++ +++ Q+ E Sbjct: 160 RKQLEVEKQKRLEEERIRSQNEERKRREREQKEREKQQKLDMEKEERRRRQQEEEKKRRE 219 Query: 4353 STVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPI 4412 K+V K+KQ ++E K I R+ T + ++ + R + + + + Sbjct: 220 EEEKRKKVE--KEKQ-EREKAAKKNIKRQQQQQRTDQQQYPREIPPRFQKMKRQQQQQQL 276 Query: 4413 FTKKMQP 4419 T + P Sbjct: 277 QTPNLPP 283 >SB_49663| Best HMM Match : TolA (HMM E-Value=0.059) Length = 591 Score = 41.5 bits (93), Expect = 0.016 Identities = 40/205 (19%), Positives = 94/205 (45%), Gaps = 13/205 (6%) Query: 4232 EKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIK 4291 E+ +++ ++ Q + + + + + +KE E ++ ++ E++ +L ELE E+ + Sbjct: 196 ERERRQQEFIKEQKDVAVQQKAQQESLKETLQEQEKETIQQLEEDFKAQLNELEVEKAKE 255 Query: 4292 ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPS 4351 ++ L E + V S + + +Y+D L+ ++ ++++ + R+ + Sbjct: 256 QTALEE------MKSFTVKSIILFSRVYSKYKDILEARNRQRKREREEELERIERVEEMQ 309 Query: 4352 ESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQ---TQERVVEGPVKPS 4408 T K + +QK+ + E KEI ++ E + E K + ++RV E ++ Sbjct: 310 RKTQEKKRIEEEEQKRKEAEEKKAKEIEQRRMEEEIKKEEEKKRKEAEEKRVKEEQIRLE 369 Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVE 4433 K +K + + E+AR E E Sbjct: 370 K----ERKRKEADDRQREEARKEEE 390 Score = 37.1 bits (82), Expect = 0.35 Identities = 43/192 (22%), Positives = 82/192 (42%), Gaps = 10/192 (5%) Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIK----EPETEWQQSVKRKKN 4274 +E + +R E KT E++++ + + E K K I+ E E + ++ KRK+ Sbjct: 297 EELERIERVEEMQRKTQEKKRIEEEEQKRKEAEEKKAKEIEQRRMEEEIKKEEEKKRKEA 356 Query: 4275 EEYYNKLQE--LENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEV 4332 EE K ++ LE E+ KE+ R+ +K K + E+ L + Sbjct: 357 EEKRVKEEQIRLEKERKRKEADDRQREEARKEEEEKRKREGEVKKRKEE-EERLVEARR- 414 Query: 4333 TEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEV--VGDKEITRKITSTETTEI 4390 EQ ++K+ ++ R + +E + +++ KE D+E R+ E Sbjct: 415 KEQEEKRKLEEQKRKEEEDRRRKEAEEKRIKEEEARLKEERRSKDEEENRRKADEERKRK 474 Query: 4391 EHKAQTQERVVE 4402 E + + RVV+ Sbjct: 475 EQEEAERNRVVQ 486 >SB_41418| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 3312 Score = 41.1 bits (92), Expect = 0.021 Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 25/149 (16%) Query: 4560 NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619 +++++ TL + ++G Y C A N G A E +V KP+ Sbjct: 2870 DEVVQTADNGTLELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEY-------KPEL--- 2919 Query: 4620 NAPPEIIEPLKDKIVAEG-QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678 + EP+ K+ G + F C G P P V+WY +P Y ++S + Sbjct: 2920 -----LEEPISVKLALYGGKGARFPCLATGNPQPRVEWY-----YRP-LYSKLSFKLPDD 2968 Query: 4679 TLRISEAFPED---EGDYKCVAYNSAGRV 4704 ++ P+D G Y CVA NS GRV Sbjct: 2969 DSQLVYIEPDDVMRSGFYYCVASNSRGRV 2997 Score = 39.5 bits (88), Expect = 0.065 Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 11/125 (8%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQS 3166 LE+ K +++G Y+C A N G AE ++ V+ KP +++ L G+ Sbjct: 2881 LELPSIKKSEAGMYTCEAANHKGSAESHYEV-IVE----YKPELLEEPISVKLALYGGKG 2935 Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226 A F C + +P ++EWY+ +P+ K D +V I SG Y C A Sbjct: 2936 ARFPC--LATGNPQPRVEWYY--RPLYSKLSFKLPDDDSQLVY-IEPDDVMRSGFYYCVA 2990 Query: 3227 YNKYG 3231 N G Sbjct: 2991 SNSRG 2995 Score = 36.7 bits (81), Expect = 0.46 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465 GK RF C TG P P V W+ R + + K+ ++S + I + SG C Sbjct: 2933 GKGARFPCLATGNPQPRVEWYY--RPLYSKLSFKLPDDDS--QLVYIEPDDVMRSGFYYC 2988 Query: 466 VARNKSGE-TAFQCRLNVIEKEQVV 489 VA N G + + RL++++ V Sbjct: 2989 VASNSRGRVVSEEGRLDILQSRGAV 3013 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Query: 2684 TLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743 T G + T D G TL + S++ ++G+YTC+A N G A S + +E + LL E Sbjct: 2865 TWRRGDEVVQTADNG--TLELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEYKPELLEE 2922 Query: 2744 SL 2745 + Sbjct: 2923 PI 2924 Score = 35.1 bits (77), Expect = 1.4 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 2/56 (3%) Query: 2956 QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011 +G T+D G TL+L + + ++G+YTC+A N +G A + V K L+E Sbjct: 2868 RGDEVVQTADNG--TLELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEYKPELLE 2921 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/130 (20%), Positives = 50/130 (38%), Gaps = 6/130 (4%) Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500 +V + N L + ++ S++G+ TC A N G + V K +++ + + Sbjct: 2872 VVQTADNGTLELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEYKPELLEEPISVKLALY 2931 Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560 G+ A G P PR+ W P+ ++ D + + I + + Sbjct: 2932 G---GKGARFPCLATGNPQPRVEWYYR--PLYSKLSFKL-PDDDSQLVYIEPDDVMRSGF 2985 Query: 561 YQCTAQNVAG 570 Y C A N G Sbjct: 2986 YYCVASNSRG 2995 Score = 33.9 bits (74), Expect = 3.2 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Query: 266 PKIAQKPRNSKLQ--EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323 P++ ++P + KL G A+F +GNP+PRV W+ R + S + + + Sbjct: 2917 PELLEEPISVKLALYGGKGARFPCLATGNPQPRVEWY---YRPLYSKLSFKLPDDDSQLV 2973 Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVT 349 + SG Y +A N G +V+ Sbjct: 2974 YIEPDDVMRSGFYYCVASNSRGRVVS 2999 Score = 33.1 bits (72), Expect = 5.7 Identities = 14/43 (32%), Positives = 26/43 (60%) Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659 LE+ + + +AG+YTC+A N G A ++ V+ + ++ EP Sbjct: 2881 LELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEYKPELLEEP 2923 Score = 32.7 bits (71), Expect = 7.5 Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 14/114 (12%) Query: 1837 EVAVNQAPRFITQ-LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895 EV V P + + ++ L G+ A + C P P RVEWY+ + L S ++ Sbjct: 2910 EVIVEYKPELLEEPISVKLALYGGKGARFPCLATGNPQP--RVEWYY--RPLYSKLSFKL 2965 Query: 1896 SNDFGFAALDILTVYGED---SGEYTCKAINNLGQAVSSI-RLNV-QSKESIIR 1944 +D ++ + +D SG Y C A N+ G+ VS RL++ QS+ ++ R Sbjct: 2966 PDDDS----QLVYIEPDDVMRSGFYYCVASNSRGRVVSEEGRLDILQSRGAVPR 3015 >SB_24813| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1218 Score = 41.1 bits (92), Expect = 0.021 Identities = 40/180 (22%), Positives = 77/180 (42%), Gaps = 10/180 (5%) Query: 4224 YQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE 4283 Y++ EL+K F + ++Q + D K + E E E+ + +K +NE ++ Sbjct: 327 YKQKIKELQKNFAK----EKQEIEDEYAHEKENIRAELENEFSEKIK-SENEALEETVKH 381 Query: 4284 LENE-QVIKESRLRESTHQYAIPGDKVTSNT----VAKSMAQRYEDNLDQTEEVTEQRVQ 4338 L+ E +KE + T ++ ++SN+ VAK E ++Q E + ++ Sbjct: 382 LQGEINYLKEQKKELETKVQSLELKSLSSNSLDFRVAKEKISDLEQKVNQLEREKSRLLE 441 Query: 4339 KKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE 4398 + K R+ + + + KQ+Q K KE+T K + T A+ Q+ Sbjct: 442 ENAEFKVRMDELESEKSELSDSVLNKQRQLLKAEEDIKELTLKDQELDVTVELRGAEKQQ 501 >SB_1718| Best HMM Match : I-set (HMM E-Value=3.8e-07) Length = 1017 Score = 41.1 bits (92), Expect = 0.021 Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 13/126 (10%) Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRPFATGSRVHTLND 3749 P P FT + + DV E + C G P+ + W + +G P A G+ Sbjct: 355 PIAPAFTPSLSRSHDVAENDDFNVTCSAS--GRPSPNVTWVNKTSGSPVAHGT------- 405 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809 G L + I AG Y CRATN G T T +T + + E L G +K Sbjct: 406 -GSAILSLLKIQRHQAGVYQCRATNDVGRGTITQDVTINVQYSSDEEYVLRTEAVG-AVK 463 Query: 3810 ELERGR 3815 ER R Sbjct: 464 HTERKR 469 Score = 36.3 bits (80), Expect = 0.61 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 8/94 (8%) Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700 AP FT L + E + R PN + W V T+G+ + G Sbjct: 357 APAFTPSLSRSHDVAENDDFNVTCSASGRPSPN--VTW----VNKTSGSPV--AHGTGSA 408 Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 LS+ ++ +G+Y C+ATN +G T + I Sbjct: 409 ILSLLKIQRHQAGVYQCRATNDVGRGTITQDVTI 442 Score = 35.5 bits (78), Expect = 1.1 Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 15/122 (12%) Query: 1823 QLEDSSRYQRREDVEVAVNQ-----APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMR 1877 QL S R+ + VNQ AP F L+ ++E + C P PN Sbjct: 332 QLAHSLHLHSRKLALLPVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPN-- 389 Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLN 1935 V W K S + T G A L +L + +G Y C+A N++G+ + +N Sbjct: 390 VTWV--NKTSGSPVAHGT----GSAILSLLKIQRHQAGVYQCRATNDVGRGTITQDVTIN 443 Query: 1936 VQ 1937 VQ Sbjct: 444 VQ 445 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/102 (23%), Positives = 38/102 (37%), Gaps = 9/102 (8%) Query: 3811 LERGRISDAPKEEPIVSTPPKFITQI-KSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869 L +++ P + + P F + +SH V E++ C + P + W Sbjct: 339 LHSRKLALLPVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPN--VTWVNKT 396 Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911 P H G L +L + +G Y CRA ND G Sbjct: 397 SGSPVAH------GTGSAILSLLKIQRHQAGVYQCRATNDVG 432 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 20/92 (21%) Query: 965 GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024 G L++ + H AG Y CRA N +G+ T + ++TI +QY Sbjct: 406 GSAILSLLKIQRHQAGVYQCRATNDVGRGTITQDVTI-----------------NVQYSS 448 Query: 1025 DASRYSKRTEE--EVKITQKPRFLGPLKGTNK 1054 D Y RTE VK T++ R+ PL+ +K Sbjct: 449 D-EEYVLRTEAVGAVKHTERKRYFVPLRFMDK 479 Score = 33.9 bits (74), Expect = 3.2 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 10/93 (10%) Query: 383 IEISEKAL--APQFV-KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439 + ++++AL AP F + + DV E C +GRP P VTW +N + Sbjct: 347 LPVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPNVTW-VNKT------SGS 399 Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 + + +G+ L + + +GV C A N G Sbjct: 400 PVAHGTGSAILSLLKIQRHQAGVYQCRATNDVG 432 Score = 33.9 bits (74), Expect = 3.2 Identities = 28/129 (21%), Positives = 53/129 (41%), Gaps = 16/129 (12%) Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158 P+ ++ P F +L+ ++ E D + C P++T W + +G Sbjct: 348 PVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPNVT--WVNK----TSGSP- 400 Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLE 2218 H G L +L +G Y C+ATN +G T +++ ++ Q+ + E Sbjct: 401 -VAHGTGSAILSLLKIQRHQAGVYQCRATNDVGRGTIT--------QDVTINVQYSSDEE 451 Query: 2219 KIRQLEAQG 2227 + + EA G Sbjct: 452 YVLRTEAVG 460 Score = 33.1 bits (72), Expect = 5.7 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 11/94 (11%) Query: 480 LNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRITW--QKDGVPIIPNPE 536 L V ++ +AP F S + +V E + + A G P+P +TW + G P+ Sbjct: 347 LPVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPNVTWVNKTSGSPV----- 401 Query: 537 LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 H G A L + + + A YQC A N G Sbjct: 402 --AHGTGSA-ILSLLKIQRHQAGVYQCRATNDVG 432 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 8/83 (9%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 P FT L ++ E + C G P+ V W + +S H G Sbjct: 358 PAFTPSLSRSHDVAENDDFNVTCSAS--GRPSPNVTW------VNKTSGSPVAHGTGSAI 409 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 +++ ++ GVY CRA+N +G Sbjct: 410 LSLLKIQRHQAGVYQCRATNDVG 432 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/83 (24%), Positives = 32/83 (38%), Gaps = 8/83 (9%) Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208 P FT + + + + C+ P++ +G P+ H T G + Sbjct: 358 PAFTPSLSRSHDVAENDDFNVTCSASGRPSPNVTWVNKTSGSPVAHGT--------GSAI 409 Query: 3209 LDIAYTQNHDSGEYVCRAYNKYG 3231 L + Q H +G Y CRA N G Sbjct: 410 LSLLKIQRHQAGVYQCRATNDVG 432 >SB_44749| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2250 Score = 41.1 bits (92), Expect = 0.021 Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 10/103 (9%) Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFD----GEPLPLIKWYRENFPIKNSPDFQIH 4460 ++ KPP+ T C +HE A +V D G PLP+++W R + N Sbjct: 1266 IRDRKPPVITCLGPDCNKTQHEIAESDVRLDCVAEGYPLPIVEWSRVGGVMPN-----YR 1320 Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503 S S+ +++QV + D+ V+ A N G +L V EK Sbjct: 1321 QLSNGSV-VLKQVKMTDTGVYQCQANNSQGGDIDRLSLHVAEK 1362 Score = 34.3 bits (75), Expect = 2.5 Identities = 30/99 (30%), Positives = 43/99 (43%), Gaps = 8/99 (8%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARL--IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768 PV T D +++ A + RL + G P VEW R G + +L+ G V Sbjct: 1272 PVITCLGPDCNKTQHEIAESDVRLDCVAEGYPLPIVEWSRVGGVMPNYRQLSN----GSV 1327 Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807 L K V D+G Y C+A N G + +L V K + Sbjct: 1328 VL--KQVKMTDTGVYQCQANNSQGGDIDRLSLHVAEKCT 1364 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 7/76 (9%) Query: 410 RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469 R DC G P P V W + +Y + N ++++ V ++D+GV C A N Sbjct: 1294 RLDCVAEGYPLPIVEWS-RVGGVMPNYR------QLSNGSVVLKQVKMTDTGVYQCQANN 1346 Query: 470 KSGETAFQCRLNVIEK 485 G + L+V EK Sbjct: 1347 SQGGDIDRLSLHVAEK 1362 >SB_26428| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 931 Score = 41.1 bits (92), Expect = 0.021 Identities = 27/105 (25%), Positives = 53/105 (50%), Gaps = 6/105 (5%) Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494 D +K V N+ ++I++ D+ T G+ + +++ + VAPK Sbjct: 827 DNQYKGRVTLLENNTMVISSFKPVDAVTYTSKLLTHDGKNIQE---SLVAVKVAVAPKLK 883 Query: 495 ER--FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537 + + ++EGE + L+ A GTP P++TW+K+G+ I+ N + Sbjct: 884 KSPPDKIIKLKEGESISLDCTASGTPAPKVTWRKNGL-ILSNQSI 927 Score = 38.7 bits (86), Expect = 0.11 Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 266 PKIAQKPRNS--KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310 PK+ + P + KL+EG SG P P+VTW KNG L N + Sbjct: 880 PKLKKSPPDKIIKLKEGESISLDCTASGTPAPKVTWRKNGLILSNQS 926 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 6/64 (9%) Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567 L +A G P+P+ITW K G PI + G S L + + A D Y+C A N Sbjct: 18 LQCKARGVPSPQITWYKPGGQPITAG----VSPISGGSQLQVTTTQDAGDYGQYKCRASN 73 Query: 568 VAGS 571 + GS Sbjct: 74 LLGS 77 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Query: 4099 EQVVEESKARCPPVFVSLPDAVT-VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155 E +V A P + S PD + ++EGE C +G P P+V W NG + N S Sbjct: 869 ESLVAVKVAVAPKLKKSPPDKIIKLKEGESISLDCTASGTPAPKVTWRKNGLILSNQS 926 Score = 33.5 bits (73), Expect = 4.3 Identities = 29/113 (25%), Positives = 43/113 (38%), Gaps = 10/113 (8%) Query: 236 FRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEG---ADAQFQVQLSGN 292 F+++ Y Q ID+ + P K ++S+ EG D + G Sbjct: 266 FQKAEDPTYANVPGQQEVIPIDQETTIIPDPAFIDKTKSSERTEGWVGYDVSLKCVTGGY 325 Query: 293 PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345 P P VTW N+ H + N T+ V + D G+YT A N G Sbjct: 326 PTPTVTW-------SNATGHVLHEEVNLTSKYVFKVKDGDFGNYTCKATNKMG 371 Score = 33.5 bits (73), Expect = 4.3 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 2/51 (3%) Query: 377 RETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTW 425 + +E + + A+AP+ K D+ + EG+ DC +G P P+VTW Sbjct: 865 KNIQESLVAVKVAVAPKLKKSPPDKIIKLKEGESISLDCTASGTPAPKVTW 915 >SB_10779| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 897 Score = 41.1 bits (92), Expect = 0.021 Identities = 32/110 (29%), Positives = 45/110 (40%), Gaps = 8/110 (7%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885 V PP + V + V C V DP L+I+WY NG + S + MG Sbjct: 308 VKDPPIIVLGPADQNVVTGDHVTMTCTVGG--DPPLKIKWYING--IDSSD----LATMG 359 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935 + AE + + C ND G KAT S ++ + +N VPR Sbjct: 360 QSRTSKITFRAEQTVKVECLVYNDLGRSSAKATASVQRRMPVTTRNMVPR 409 Score = 37.1 bits (82), Expect = 0.35 Identities = 36/136 (26%), Positives = 51/136 (37%), Gaps = 14/136 (10%) Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 D++V G C V G P ++ W+IN D L + IT Sbjct: 320 DQNVVTGDHVTMTCTVGGDPPLKIKWYINGIDSSD------LATMGQSRTSKIT-FRAEQ 372 Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER-----FSTLNVRE--GEPVVLNA 512 + V C+ N G ++ + +V + V V R +TLN G V L Sbjct: 373 TVKVECLVYNDLGRSSAKATASVQRRMPVTTRNMVPRKALITIATLNQTAGIGANVTLRC 432 Query: 513 RAVGTPTPRITWQKDG 528 A GTP +I W DG Sbjct: 433 SATGTPPMKIRWFIDG 448 Score = 36.3 bits (80), Expect = 0.61 Identities = 77/350 (22%), Positives = 121/350 (34%), Gaps = 39/350 (11%) Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVK-----PSKPPIFTKKMQPC 4420 KQ+ + IT+T + K +T P K P FT + Sbjct: 164 KQSLTSTAPTDSLPTHITATGM-HLSQKPETTATATASPTKVVANVPKTVLSFTNPLGNH 222 Query: 4421 RVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIHTFST---KSILIIRQVFVE 4476 V RF G + IKW I + PD QI ++ KS L +++ E Sbjct: 223 TVAVGSSQRFVCHVKGTRKRVPIKWTWNGRIISDDPD-QIDIWNRPKRKSTLTLKKTKKE 281 Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV-PPSFTLTAQNVNVTSGQLVRLDT 4535 DS ++ A G V+ + G + PP L + NV +G V + Sbjct: 282 DSGMYGCHA----GIGMIG----VDSIQMYGFLSVKDPPIIVLGPADQNVVTGDHVTMTC 333 Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595 V G P+ + W NG I + L G + + + K EC+ N G + Sbjct: 334 TVGGDPPLKIKWYING------IDSSDLATMGQSRTSKITFRAEQTVKVECLVYNDLGRS 387 Query: 4596 RCDAECVVS--LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653 A V +P T P+ KA I ++ G + C G P Sbjct: 388 SAKATASVQRRMPVTTRNMVPR-KAL-----ITIATLNQTAGIGANVTLRCSATGTPPMK 441 Query: 4654 VQWY-KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 ++W+ G + S +T +++ + E KC+A N G Sbjct: 442 IRWFIDGRYYDGEQNRGRESMYTSSFTFTVNKEYTE----VKCLAQNPYG 487 Score = 34.3 bits (75), Expect = 2.5 Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 10/117 (8%) Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847 G N+ C+ + P +KI WF + + G + + Y S T T ++ Sbjct: 425 GANVTLRCSATGT--PPMKIRWFIDGRYY-DGEQNRGRESM-YTS-SFTFTVNKEYTEVK 479 Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQG-----KAGLEAVEQAEEARLAKGR 2899 C A N G SG +R + + +Y ++PQG A +EAV Q+ + G+ Sbjct: 480 CLAQNPYGIDNRSGVIRPSEEGGLYGVWRNPQGDTVLFHADMEAVSQSPWDQFMPGK 536 Score = 33.1 bits (72), Expect = 5.7 Identities = 37/157 (23%), Positives = 62/157 (39%), Gaps = 7/157 (4%) Query: 3779 ATTTAKITCSAKRDIVLESQLPQGMS-GEKIKELERGRISDAPKEEPIVSTPPKFITQIK 3837 +TT +T +A D + GM +K + S + T F + Sbjct: 161 STTKQSLTSTAPTDSLPTHITATGMHLSQKPETTATATASPTKVVANVPKTVLSFTNPLG 220 Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD--MGFVSLDILYVY 3895 +HTV RF C V+ ++ I+W NG+++ +++ +L + Sbjct: 221 NHTVAVGSSQRFVCHVKGTR-KRVPIKWTWNGRIISDDPDQIDIWNRPKRKSTLTLKKTK 279 Query: 3896 AEDSGEYICRA-VNDFGEDFTK--ATISCKKLPDIIL 3929 EDSG Y C A + G D + +S K P I+L Sbjct: 280 KEDSGMYGCHAGIGMIGVDSIQMYGFLSVKDPPIIVL 316 Score = 33.1 bits (72), Expect = 5.7 Identities = 47/186 (25%), Positives = 70/186 (37%), Gaps = 12/186 (6%) Query: 394 FVKVCQDRDVTEGKMTRFDCRVTG-RPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LM 451 F + V G RF C V G R + W N R I DD + + N + L Sbjct: 215 FTNPLGNHTVAVGSSQRFVCHVKGTRKRVPIKWTWNGRIISDDPDQIDIWNRPKRKSTLT 274 Query: 452 ITNVTLSDSGVVTCVAR-NKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 + DSG+ C A G + Q + K+ P V + NV G+ V + Sbjct: 275 LKKTKKEDSGMYGCHAGIGMIGVDSIQMYGFLSVKDP---PIIVLGPADQNVVTGDHVTM 331 Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570 G P +I W +G I + +L T G + T I +A +C N G Sbjct: 332 TCTVGGDPPLKIKWYING---IDSSDLA--TMGQSRTSKI-TFRAEQTVKVECLVYNDLG 385 Query: 571 STATRA 576 ++ +A Sbjct: 386 RSSAKA 391 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060 G P MK+ WF +G+ + + Y + +F + ++ E C A N YG+D Sbjct: 436 GTPPMKIRWFIDGR--YYDGEQNRGRESMYTS-SFTFTVNKEYTEVKCLAQNPYGIDNRS 492 Query: 4061 AVIKTTGKPGI 4071 VI+ + + G+ Sbjct: 493 GVIRPSEEGGL 503 >SB_50998| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 156 Score = 40.7 bits (91), Expect = 0.028 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 11/86 (12%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550 P + VR GE + L G PTP ++W K G H+ GG + Sbjct: 71 PPEITPIQNTTVRAGETITLTCVLAGNPTPSVSWSKAGSG---------HSTGG-NVFTK 120 Query: 551 PRAKASDAAWYQCTAQN-VAGSTATR 575 A +D Y CTA N V G+T TR Sbjct: 121 AGATKADTGQYVCTAVNTVTGNTQTR 146 Score = 37.1 bits (82), Expect = 0.35 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 SL K+ + T+ PPEI P+++ V G+ I +C + G P P+V W K Sbjct: 54 SLKRAKNS-RHHTQYNTDPPEIT-PIQNTTVRAGETITLTCVLAGNPTPSVSWSK 106 >SB_42485| Best HMM Match : Pkinase_Tyr (HMM E-Value=0) Length = 1565 Score = 40.7 bits (91), Expect = 0.028 Identities = 44/183 (24%), Positives = 80/183 (43%), Gaps = 22/183 (12%) Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 D+G+Y+CVAINS G+ V + +++ K ++ PL VA G Sbjct: 336 DAGEYKCVAINSQGQGSATISLHVKVSSSEFK------------FLVTPLPFATVAFGAN 383 Query: 4640 IEFSCKIVGKPLPTVQWY-KGDKLIKPSKYFQ---MSRTADEYTLRISEAFPEDEGDYKC 4695 E C+ K T ++ K KY + + + D Y++ D G Y+C Sbjct: 384 YEMDCRTNDKNATTSLFFRKNPTFPSKEKYTEPKKLIKVGDIYSIIYFGV--NDFGAYQC 441 Query: 4696 VAYNSAGRVTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754 A N++G V ++ + +PD ++ + P + +V+ GQ S + T++W Sbjct: 442 RATNASGFVIQNVEVNLYGRPDVTPDV-KIVPDQAVVLTIGQ--HVNLTCISATQTTLKW 498 Query: 4755 LRE 4757 L++ Sbjct: 499 LKQ 501 Score = 39.5 bits (88), Expect = 0.065 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 9/119 (7%) Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748 D G+YKCVA NS G+ + L V + ++ +TPL V G + + K Sbjct: 336 DAGEYKCVAINSQGQGSATISLHV-KVSSSEFKFLVTPLPFATVAFGANYEMDCRTNDKN 394 Query: 4749 KPTIQWLREGALIPETPDF----QMIHEGN-NAVLLIGNTYEEDTGTFTCRATTAAGQV 4802 T + R+ P + ++I G+ +++ G D G + CRAT A+G V Sbjct: 395 ATTSLFFRKNPTFPSKEKYTEPKKLIKVGDIYSIIYFG---VNDFGAYQCRATNASGFV 450 Score = 39.5 bits (88), Expect = 0.065 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 8/88 (9%) Query: 480 LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539 LNV EK ++V+PK T+ VR E + A G P P++ W + G + Sbjct: 907 LNVPEKAKIVSPKS----KTVLVRPEEHFNQSCHASGNPVPKVMWMRPG----KAGTKVL 958 Query: 540 HTDGGASTLDIPRAKASDAAWYQCTAQN 567 T G++ L I + D A Y C A N Sbjct: 959 STGQGSALLVIDKMSKDDIANYTCNATN 986 Score = 37.1 bits (82), Expect = 0.35 Identities = 36/144 (25%), Positives = 53/144 (36%), Gaps = 10/144 (6%) Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167 L I G + D+G Y C A N GQ ++ L K + +F + G + Sbjct: 327 LVIRGVEGADAGEYKCVAINSQGQGSATISLHV--KVSSSEFKFLVTPLPFATVAFGANY 384 Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHS----TRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223 +C +D + + P S T K + G + I Y +D G Y Sbjct: 385 EMDCR---TNDKNATTSLFFRKNPTFPSKEKYTEPKKLIKVG-DIYSIIYFGVNDFGAYQ 440 Query: 3224 CRAYNKYGEDFTRATINCYGKGGV 3247 CRA N G +N YG+ V Sbjct: 441 CRATNASGFVIQNVEVNLYGRPDV 464 Score = 36.7 bits (81), Expect = 0.46 Identities = 19/40 (47%), Positives = 25/40 (62%) Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941 A L I V G D+GEY C AIN+ GQ ++I L+V+ S Sbjct: 325 AQLVIRGVEGADAGEYKCVAINSQGQGSATISLHVKVSSS 364 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851 HF + S +P K+ W +P +GT+ ST S + L I ++D YTC AT Sbjct: 930 HFNQSCHASGNPVPKVMWM---RPGKAGTKVLSTGQGSAL-LVIDKMSKDDIANYTCNAT 985 Query: 2852 NSK 2854 N K Sbjct: 986 NYK 988 Score = 33.1 bits (72), Expect = 5.7 Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 4/61 (6%) Query: 3714 HFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT 3773 HF+ G+P ++ W RP G++V + G L ID + D YTC AT Sbjct: 930 HFNQSCHASGNPVPKVMWM---RPGKAGTKVLSTGQ-GSALLVIDKMSKDDIANYTCNAT 985 Query: 3774 N 3774 N Sbjct: 986 N 986 >SB_10883| Best HMM Match : ig (HMM E-Value=7.00649e-43) Length = 1280 Score = 40.7 bits (91), Expect = 0.028 Identities = 35/125 (28%), Positives = 48/125 (38%), Gaps = 13/125 (10%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L I +V D G + GET F+ ++ V+A V + + V + Sbjct: 941 LTIKDVQPQDVGEYAMHLADDEGETTFEASKFTLD---VLAHPSVTH-ANITVNKTNTAE 996 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 L A G P P +TW + G + G TL K SD Y CTA N Sbjct: 997 LMCSATGNPKPNVTWTRSG---------KKDVLGTGETLTFSNVKISDGGCYVCTATNNI 1047 Query: 570 GSTAT 574 GS A+ Sbjct: 1048 GSGAS 1052 Score = 39.5 bits (88), Expect = 0.065 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 11/112 (9%) Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522 +T + +N + A + + + + V P + + V + VL A G PTP + Sbjct: 254 ITLIIKNVQPQDAGEYAMRLSDDFGDVPPSVTH--ANITVNKTNTAVLMCSATGNPTPNV 311 Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574 TW + G E + T TL K SD Y CTA N GS A+ Sbjct: 312 TWTRSG------KEDVLWT---GETLTFRDVKISDGGCYVCTATNNIGSGAS 354 Score = 39.1 bits (87), Expect = 0.086 Identities = 66/296 (22%), Positives = 105/296 (35%), Gaps = 47/296 (15%) Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576 ++T N+ V L TG +V W ++GKK +L T T ++ Sbjct: 981 SVTHANITVNKTNTAELMCSATGNPKPNVTWTRSGKK-------DVLGTGETLTFSNVKI 1033 Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636 D G Y C A N+ G C+ + KP T I+ Sbjct: 1034 --SDGGCYVCTATNNIGSGASGTVCL----TVRYKP-VHTNITGVESYIVRQC------- 1079 Query: 4637 GQAIEFSCKIVGKP-LPTVQWYKGDKLIKPSKYFQMSR-TADEYTLRISEAFPEDEGDYK 4694 G AI +C VG+P L T Y + LI+ + D + + P ++ Sbjct: 1080 GAAISLTCSAVGEPQLITYHLYMDNLLIRKNINGMFHNILLDSVGIHLLTCVPINDAG-- 1137 Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754 V N + + V KL ++TPLR V EG F W Sbjct: 1138 -VGENRSVSMNVTEKLPTI---------SITPLR-ATVNEGSVVVFTCLAIGFQSFKNFW 1186 Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810 ++G + +G+ + L + + +D+G +TC T+ G +A L V Sbjct: 1187 KKDG-----------VFKGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDV 1231 Score = 38.3 bits (85), Expect = 0.15 Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 33/178 (18%) Query: 406 GKMTRFDCRVTGRPYPEVTW--FINDRQIRDDYN---HKILVNESGNHALMITNVTLSDS 460 G C G P +T+ ++++ IR + N H IL++ G H ++T V ++D+ Sbjct: 382 GAAISLTCSAVGEPQL-ITYHLYMDNLLIRKNINGMFHNILLDSVGIH--LLTCVPINDA 438 Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520 GV N+S +NV EK ++ + +T+N EG VV A+G + Sbjct: 439 GV----GENRS------VSINVTEKLPTISITHLR--ATVN--EGSVVVFTCLAIGFQSF 484 Query: 521 RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + W+KDGV G S+L + D+ Y C + G+T A L Sbjct: 485 KNFWKKDGV-----------FRGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASL 531 Score = 37.9 bits (84), Expect = 0.20 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%) Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725 S+Y + T + TL I + P+D G+Y + G T A K T A P++T Sbjct: 927 SRYSISTATFNPITLTIKDVQPQDVGEYAMHLADDEGETTFEAS-KFTLDVLAH--PSVT 983 Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785 +I V + A+ T KP + W R G D G L N Sbjct: 984 H-ANITVNKTNTAELMCSATGNPKPNVTWTRSG-----KKDVL----GTGETLTFSNVKI 1033 Query: 4786 EDTGTFTCRATTAAG 4800 D G + C AT G Sbjct: 1034 SDGGCYVCTATNNIG 1048 Score = 37.9 bits (84), Expect = 0.20 Identities = 47/178 (26%), Positives = 76/178 (42%), Gaps = 33/178 (18%) Query: 406 GKMTRFDCRVTGRPYPEVTW--FINDRQIRDDYN---HKILVNESGNHALMITNVTLSDS 460 G C G P +T+ ++++ IR + N H IL++ G H ++T V ++D+ Sbjct: 1080 GAAISLTCSAVGEPQL-ITYHLYMDNLLIRKNINGMFHNILLDSVGIH--LLTCVPINDA 1136 Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520 GV N+S +NV EK ++ +T+N EG VV A+G + Sbjct: 1137 GV----GENRS------VSMNVTEKLPTIS--ITPLRATVN--EGSVVVFTCLAIGFQSF 1182 Query: 521 RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 + W+KDGV G S+L + D+ Y C + G+T A L Sbjct: 1183 KNFWKKDGV-----------FKGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASL 1229 Score = 36.7 bits (81), Expect = 0.46 Identities = 16/45 (35%), Positives = 23/45 (51%) Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM 4164 +TV + A C TG+PKP V W +G V G+ LT+ + Sbjct: 987 ITVNKTNTAELMCSATGNPKPNVTWTRSGKKDVLGTGETLTFSNV 1031 Score = 35.9 bits (79), Expect = 0.80 Identities = 14/34 (41%), Positives = 23/34 (67%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +L+++S+ DDSG YTC T+ G + TAS+ + Sbjct: 500 SLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDV 533 Score = 35.9 bits (79), Expect = 0.80 Identities = 14/34 (41%), Positives = 23/34 (67%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +L+++S+ DDSG YTC T+ G + TAS+ + Sbjct: 1198 SLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDV 1231 Score = 34.3 bits (75), Expect = 2.5 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 13/107 (12%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C TG P P VTW R ++D V +G L +V +SD G C A N G Sbjct: 301 CSATGNPTPNVTW---TRSGKED------VLWTG-ETLTFRDVKISDGGCYVCTATNNIG 350 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTP 518 A ++ + V + + NVR+ G + L AVG P Sbjct: 351 SGASGIVCLTVQYKPVHTN--ITGVESYNVRQCGAAISLTCSAVGEP 395 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 9/63 (14%) Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342 A+ +GNP+P VTW ++G K +++ T TL N + SD G Y A N Sbjct: 995 AELMCSATGNPKPNVTWTRSG-------KKDVLGTGE--TLTFSNVKISDGGCYVCTATN 1045 Query: 343 PNG 345 G Sbjct: 1046 NIG 1048 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 11/81 (13%) Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324 PP + N + + A +GNP P VTW ++G K +++ T TL Sbjct: 281 PPSVTHA--NITVNKTNTAVLMCSATGNPTPNVTWTRSG-------KEDVLWTGE--TLT 329 Query: 325 VRNTQKSDSGHYTLLAENPNG 345 R+ + SD G Y A N G Sbjct: 330 FRDVKISDGGCYVCTATNNIG 350 Score = 33.1 bits (72), Expect = 5.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407 ++ D +L L SV +DSG YTC T+ G + + +L VI K + Sbjct: 1192 FKGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDVIYKPE 1236 Score = 32.7 bits (71), Expect = 7.5 Identities = 17/42 (40%), Positives = 24/42 (57%) Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407 D +L L SV +DSG YTC T+ G + + +L VI K + Sbjct: 497 DGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDVIYKPE 538 Score = 32.3 bits (70), Expect = 9.9 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 17/117 (14%) Query: 1690 QLEDTSKYQRHSAQDEVIT--QAPVFTMPM------KDIRVAENQAAHFEARLIPVGDPK 1741 Q +D +Y H A DE T +A FT+ + + N+ E G+PK Sbjct: 947 QPQDVGEYAMHLADDEGETTFEASKFTLDVLAHPSVTHANITVNKTNTAELMCSATGNPK 1006 Query: 1742 LRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798 V W R+G + L T L V D G Y C A N +G + + Sbjct: 1007 PNVTWTRSG----KKDVLGTGE-----TLTFSNVKISDGGCYVCTATNNIGSGASGT 1054 Score = 32.3 bits (70), Expect = 9.9 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 10/63 (15%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C TG P P VTW R + D V +G L +NV +SD G C A N G Sbjct: 999 CSATGNPKPNVTW---TRSGKKD------VLGTG-ETLTFSNVKISDGGCYVCTATNNIG 1048 Query: 473 ETA 475 A Sbjct: 1049 SGA 1051 >SB_43084| Best HMM Match : ig (HMM E-Value=9.7e-23) Length = 960 Score = 40.7 bits (91), Expect = 0.028 Identities = 35/125 (28%), Positives = 48/125 (38%), Gaps = 13/125 (10%) Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509 L I +V D G + GET F+ ++ V+A V + + V + Sbjct: 83 LTIKDVQPQDVGEYAMHLADDEGETTFEASKFTLD---VLAHPSVTH-ANITVNKTNTAE 138 Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569 L A G P P +TW + G + G TL K SD Y CTA N Sbjct: 139 LMCSATGNPKPNVTWTRSG---------KKDVLGTGETLTFSNVKISDGGCYVCTATNNI 189 Query: 570 GSTAT 574 GS A+ Sbjct: 190 GSGAS 194 Score = 37.9 bits (84), Expect = 0.20 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%) Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725 S+Y + T + TL I + P+D G+Y + G T A K T A P++T Sbjct: 69 SRYSISTATFNPITLTIKDVQPQDVGEYAMHLADDEGETTFEAS-KFTLDVLAH--PSVT 125 Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785 +I V + A+ T KP + W R G D G L N Sbjct: 126 H-ANITVNKTNTAELMCSATGNPKPNVTWTRSG-----KKDVL----GTGETLTFSNVKI 175 Query: 4786 EDTGTFTCRATTAAG 4800 D G + C AT G Sbjct: 176 SDGGCYVCTATNNIG 190 Score = 36.7 bits (81), Expect = 0.46 Identities = 16/45 (35%), Positives = 23/45 (51%) Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM 4164 +TV + A C TG+PKP V W +G V G+ LT+ + Sbjct: 129 ITVNKTNTAELMCSATGNPKPNVTWTRSGKKDVLGTGETLTFSNV 173 Score = 36.7 bits (81), Expect = 0.46 Identities = 14/34 (41%), Positives = 23/34 (67%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +L+++S+ DDSG YTC T+ G + TAS+ + Sbjct: 340 SLTLSSVGRDDSGNYTCNVTSTCGTTIKTASLDV 373 Score = 35.5 bits (78), Expect = 1.1 Identities = 33/107 (30%), Positives = 43/107 (40%), Gaps = 13/107 (12%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C TG P P VTW R + D V +G L +NV +SD G C A N G Sbjct: 141 CSATGNPKPNVTW---TRSGKKD------VLGTG-ETLTFSNVKISDGGCYVCTATNNIG 190 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTP 518 A + + V + + NVR+ G + L AVG P Sbjct: 191 SGASGTVCLTVRYKPVHTN--ITGVESYNVRQCGAAISLTCSAVGEP 235 Score = 35.1 bits (77), Expect = 1.4 Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 27/149 (18%) Query: 430 RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489 R+ D H I+++ H ++T V ++D+GV N+S +NV EK + Sbjct: 250 RKNNDGVFHNIILDAVERH--LLTCVPINDAGV----GENRS------VSVNVTEKLPTI 297 Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549 + + +T+N EG VV A+G + + W+KDGV G S+L Sbjct: 298 SITHLR--ATVN--EGSVVVFTCLAIGFQSLKNFWKKDGV-----------FKGDGSSLT 342 Query: 550 IPRAKASDAAWYQCTAQNVAGSTATRARL 578 + D+ Y C + G+T A L Sbjct: 343 LSSVGRDDSGNYTCNVTSTCGTTIKTASL 371 Score = 33.9 bits (74), Expect = 3.2 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 9/63 (14%) Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342 A+ +GNP+P VTW ++G K +++ T TL N + SD G Y A N Sbjct: 137 AELMCSATGNPKPNVTWTRSG-------KKDVLGTGE--TLTFSNVKISDGGCYVCTATN 187 Query: 343 PNG 345 G Sbjct: 188 NIG 190 Score = 33.9 bits (74), Expect = 3.2 Identities = 17/45 (37%), Positives = 26/45 (57%) Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407 ++ D +L L SV +DSG YTC T+ G + + +L VI K + Sbjct: 334 FKGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTIKTASLDVIYKPE 378 Score = 32.3 bits (70), Expect = 9.9 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 17/117 (14%) Query: 1690 QLEDTSKYQRHSAQDEVIT--QAPVFTMPM------KDIRVAENQAAHFEARLIPVGDPK 1741 Q +D +Y H A DE T +A FT+ + + N+ E G+PK Sbjct: 89 QPQDVGEYAMHLADDEGETTFEASKFTLDVLAHPSVTHANITVNKTNTAELMCSATGNPK 148 Query: 1742 LRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798 V W R+G + L T L V D G Y C A N +G + + Sbjct: 149 PNVTWTRSG----KKDVLGTGE-----TLTFSNVKISDGGCYVCTATNNIGSGASGT 196 >SB_37145| Best HMM Match : ig (HMM E-Value=8e-07) Length = 323 Score = 40.3 bits (90), Expect = 0.037 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 9/74 (12%) Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537 S F V EN GT K +A + + K PS T N+ VT G LV L Sbjct: 212 SVQFTCVPENDVGTGK-NATVTINVK--------AAPSITFITANMTVTEGSLVNLQCNT 262 Query: 4538 TGTKPIDVYWLKNG 4551 +G+ P++V W K G Sbjct: 263 SGSLPLNVSWSKVG 276 Score = 35.9 bits (79), Expect = 0.80 Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 18/163 (11%) Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVV------SLPATKDKPKPQTKAANAPP 4623 TL+I + PQD+G+Y + GE +A P + T N P Sbjct: 11 TLIIKDVQPQDAGEYAMTLADDGGETTSEASKFTLDVLGGDFPCRRFIDLRITARCNVPV 70 Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683 VAEG + C G P + I + Q+S T IS Sbjct: 71 TSHYQGSVMNVAEGSEVMLECNATGSS-PNI-------TIGRNGEAQLSTTGKHTFAAIS 122 Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP 4726 +EG Y+C+ +N TV + +T + +N LTP Sbjct: 123 R---REEGSYRCIVHNGGECPTVYSTTNITVNYKPEN-TTLTP 161 >SB_28081| Best HMM Match : ig (HMM E-Value=2e-08) Length = 293 Score = 40.3 bits (90), Expect = 0.037 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517 S S V C A+NK+G ++ IE E + P + S+L G+ L+ A G Sbjct: 91 SGSNVFRCDAQNKAGSDTET--IDSIEIEGI--PVITSKQSSLTFNNGDQAFLHCNATGY 146 Query: 518 PTPRITWQKDG 528 PTP +TW + G Sbjct: 147 PTPNVTWIRLG 157 Score = 34.3 bits (75), Expect = 2.5 Identities = 14/39 (35%), Positives = 20/39 (51%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149 PV S ++T G+ A C TG+P P V W+ G+ Sbjct: 120 PVITSKQSSLTFNNGDQAFLHCNATGYPTPNVTWIRLGD 158 >SB_21023| Best HMM Match : I-set (HMM E-Value=2e-07) Length = 175 Score = 40.3 bits (90), Expect = 0.037 Identities = 34/144 (23%), Positives = 56/144 (38%), Gaps = 13/144 (9%) Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 PPEII P+++ V G+ I +C + G P P+V W K S + + +T Sbjct: 34 PPEII-PIQNTTVRAGETITLTCAVAGNPTPSVFWSKAGS--------GHSTSGNVFTK- 83 Query: 4682 ISEAFPEDEGDYKCVAYNS-AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740 + A D G Y C A N+ G ++ + +P + + G + Sbjct: 84 -ASATKADTGQYVCTAVNTVTGNTQTRTASTYVMVKYKPSILSKSPDQTVNETTGS-LKL 141 Query: 4741 KTQITSKIKPTIQWLREGALIPET 4764 PT W R+G ++ T Sbjct: 142 TCNSDGYPAPTSTWSRDGVVVSRT 165 Score = 37.9 bits (84), Expect = 0.20 Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 11/75 (14%) Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561 VR GE + L G PTP + W K G H+ G + A +D Y Sbjct: 45 VRAGETITLTCAVAGNPTPSVFWSKAGSG---------HSTSG-NVFTKASATKADTGQY 94 Query: 562 QCTAQN-VAGSTATR 575 CTA N V G+T TR Sbjct: 95 VCTAVNTVTGNTQTR 109 Score = 36.7 bits (81), Expect = 0.46 Identities = 35/141 (24%), Positives = 55/141 (39%), Gaps = 14/141 (9%) Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451 P+ + + Q+ V G+ C V G P P V W + H + SGN Sbjct: 35 PEIIPI-QNTTVRAGETITLTCAVAGNPTPSVFW------SKAGSGH----STSGN-VFT 82 Query: 452 ITNVTLSDSGVVTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510 + T +D+G C A N +G T + + + + T+N G + L Sbjct: 83 KASATKADTGQYVCTAVNTVTGNTQTRTASTYVMVKYKPSILSKSPDQTVNETTGS-LKL 141 Query: 511 NARAVGTPTPRITWQKDGVPI 531 + G P P TW +DGV + Sbjct: 142 TCNSDGYPAPTSTWSRDGVVV 162 >SB_42222| Best HMM Match : ig (HMM E-Value=2.1e-17) Length = 364 Score = 40.3 bits (90), Expect = 0.037 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%) Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517 S S V C A+NK+G ++ IE E + P + S+L G+ L+ A G Sbjct: 77 SGSNVFRCDAQNKAGSDTET--IDSIEIEGI--PVITSKQSSLTFNNGDQAFLHCNATGY 132 Query: 518 PTPRITWQKDG 528 PTP +TW + G Sbjct: 133 PTPNVTWIRLG 143 Score = 38.7 bits (86), Expect = 0.11 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 4083 SIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRV 4142 SIE I E V E + K PV S ++T EG+ A F C TG P P V Sbjct: 254 SIE-IEGKERKSNVRKENRRQGKKIEGIPVITSKLSSLTFNEGDQASFHCNATGFPTPNV 312 Query: 4143 MWLLNGN 4149 W+ G+ Sbjct: 313 TWIRLGD 319 Score = 34.3 bits (75), Expect = 2.5 Identities = 14/39 (35%), Positives = 20/39 (51%) Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149 PV S ++T G+ A C TG+P P V W+ G+ Sbjct: 106 PVITSKQSSLTFNNGDQAFLHCNATGYPTPNVTWIRLGD 144 Score = 33.5 bits (73), Expect = 4.3 Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528 P + S+L EG+ + A G PTP +TW + G Sbjct: 281 PVITSKLSSLTFNEGDQASFHCNATGFPTPNVTWIRLG 318 >SB_37828| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 358 Score = 40.3 bits (90), Expect = 0.037 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 4/75 (5%) Query: 3840 TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899 T E V EC +P+ I+W R +LPS T+ SL I V A D+ Sbjct: 279 TAVEGTSVSLECHFATSTNPE--IDWERLNGVLPSERA--TLSREPHSSLVIARVEASDA 334 Query: 3900 GEYICRAVNDFGEDF 3914 G Y C A ND+G F Sbjct: 335 GRYKCYAANDYGSIF 349 Score = 39.1 bits (87), Expect = 0.086 Identities = 39/133 (29%), Positives = 64/133 (48%), Gaps = 16/133 (12%) Query: 441 LVNESGNHALMITNVTLSDSGVVTC-VARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499 +VN S A+++++VT D+G C +G+TA +L + F +R + Sbjct: 229 MVNSS---AILVSSVTGQDAGRYRCKTMATSTGDTAGLFKLGT-----PMNCVFKDRITA 280 Query: 500 LNVREGEPVVLNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558 + EG V L + P I W++ +GV +P+ + + +S L I R +ASDA Sbjct: 281 V---EGTSVSLECHFATSTNPEIDWERLNGV--LPSERATLSREPHSS-LVIARVEASDA 334 Query: 559 AWYQCTAQNVAGS 571 Y+C A N GS Sbjct: 335 GRYKCYAANDYGS 347 Score = 37.5 bits (83), Expect = 0.26 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 3/76 (3%) Query: 4630 KDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688 KD+I A EG ++ C P + W + + ++ PS+ +SR +L I+ Sbjct: 275 KDRITAVEGTSVSLECHFATSTNPEIDWERLNGVL-PSERATLSREPHS-SLVIARVEAS 332 Query: 4689 DEGDYKCVAYNSAGRV 4704 D G YKC A N G + Sbjct: 333 DAGRYKCYAANDYGSI 348 Score = 37.5 bits (83), Expect = 0.26 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 4/76 (5%) Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840 + I EG ++ EC+ S +P +I+W N LPS S S SL I Sbjct: 276 DRITAVEGTSVSLECHFATSTNP--EIDWERLNGVLPSERATLSREPHS--SLVIARVEA 331 Query: 2841 EDSGIYTCKATNSKGS 2856 D+G Y C A N GS Sbjct: 332 SDAGRYKCYAANDYGS 347 Score = 35.5 bits (78), Expect = 1.1 Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 6/78 (7%) Query: 3702 KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH-NGRPFATGSRVHTLNDFGFIALDIDYI 3760 KD I EG V +C +P IDW NG S TL+ +L I + Sbjct: 275 KDRITAVEGTSVSLECHFATSTNP--EIDWERLNG---VLPSERATLSREPHSSLVIARV 329 Query: 3761 YARDAGEYTCRATNKWGS 3778 A DAG Y C A N +GS Sbjct: 330 EASDAGRYKCYAANDYGS 347 >SB_26678| Best HMM Match : I-set (HMM E-Value=1e-07) Length = 563 Score = 40.3 bits (90), Expect = 0.037 Identities = 36/143 (25%), Positives = 55/143 (38%), Gaps = 10/143 (6%) Query: 4575 EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV 4634 + PQ+ +E A N+ GE D C KP T P I PL D Sbjct: 121 DGQPQER-VHEICARNNIGEIH-DHYCSDRYTTAAICKKPATGGFFGTPVIFSPLPDVDA 178 Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694 E + I C+ +G + + W D L++ +R+ + L IS G ++ Sbjct: 179 YENETITLQCQAIGDAVIIIAWLHNDTLVQ-------NRSVNT-ALVISNIPLNMSGSWR 230 Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQ 4717 CVA N G + V +P + Sbjct: 231 CVASNHLGSQNKTFYVDVKKPSE 253 Score = 36.3 bits (80), Expect = 0.61 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 11/83 (13%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 PV PL ++D E +T C+ I GD + + W N+ L+++ S T + Sbjct: 167 PVIFSPLPDVD-AYENETITLQCQAI--GDAVIIIAWLHNDTLVQNRSVNT--------A 215 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 + IS++ G + C ASN LG Sbjct: 216 LVISNIPLNMSGSWRCVASNHLG 238 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 9/73 (12%) Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 D D E + C+ G + W ND ++ N S N AL+I+N+ L+ Sbjct: 175 DVDAYENETITLQCQAIGDAVIIIAWLHNDTLVQ---------NRSVNTALVISNIPLNM 225 Query: 460 SGVVTCVARNKSG 472 SG CVA N G Sbjct: 226 SGSWRCVASNHLG 238 >SB_10221| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 766 Score = 40.3 bits (90), Expect = 0.037 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 10/96 (10%) Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682 P I+ L D V +G++I C+ G + + W + L++ +RT D T + Sbjct: 589 PIILPSLPDVEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQ-------NRTKD--TALV 639 Query: 4683 SEAFP-EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717 + P +G +KCVA N G+ T + L VT P Q Sbjct: 640 FDKVPLTAKGSWKCVASNHLGQDTKSFYLHVTNPVQ 675 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 10/93 (10%) Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562 KR+ G P + +V V G+ +RL + TG I + WL N VQ ++ Sbjct: 578 KRKADGGYFGTPIILPSLPDVEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQNRTKD-- 635 Query: 4563 LEEDGTYTLLILEAYPQDS-GKYECVAINSAGE 4594 T L+ + P + G ++CVA N G+ Sbjct: 636 -------TALVFDKVPLTAKGSWKCVASNHLGQ 661 Score = 35.1 bits (77), Expect = 1.4 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 9/88 (10%) Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 D +V +GK R C TG + W +N+ ++ N + + AL+ V L+ Sbjct: 597 DVEVEKGKSIRLQCEATGDAVIYIAWL---------HNNTLVQNRTKDTALVFDKVPLTA 647 Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQ 487 G CVA N G+ L+V Q Sbjct: 648 KGSWKCVASNHLGQDTKSFYLHVTNPVQ 675 Score = 32.7 bits (71), Expect = 7.5 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 1/47 (2%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156 P + SLPD V VE+G+ R C TG + WL N + N ++ Sbjct: 589 PIILPSLPD-VEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQNRTK 634 >SB_10219| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 929 Score = 40.3 bits (90), Expect = 0.037 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 10/96 (10%) Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682 P I+ L D V +G++I C+ G + + W + L++ +RT D T + Sbjct: 752 PIILPSLPDVEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQ-------NRTKD--TALV 802 Query: 4683 SEAFP-EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717 + P +G +KCVA N G+ T + L VT P Q Sbjct: 803 FDKVPLTAKGSWKCVASNHLGQDTKSFYLHVTDPVQ 838 Score = 35.9 bits (79), Expect = 0.80 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 10/93 (10%) Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562 KR+ G P + +V V G+ +RL + TG I + WL N VQ ++ Sbjct: 741 KRKADGGYFGTPIILPSLPDVEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQNRTKD-- 798 Query: 4563 LEEDGTYTLLILEAYPQDS-GKYECVAINSAGE 4594 T L+ + P + G ++CVA N G+ Sbjct: 799 -------TALVFDKVPLTAKGSWKCVASNHLGQ 824 Score = 35.9 bits (79), Expect = 0.80 Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 9/88 (10%) Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 D +V +GK R C TG + W +N+ ++ N + + AL+ V L+ Sbjct: 760 DVEVEKGKSIRLQCEATGDAVIYIAWL---------HNNTLVQNRTKDTALVFDKVPLTA 810 Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQ 487 G CVA N G+ L+V + Q Sbjct: 811 KGSWKCVASNHLGQDTKSFYLHVTDPVQ 838 Score = 32.7 bits (71), Expect = 7.5 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 1/47 (2%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156 P + SLPD V VE+G+ R C TG + WL N + N ++ Sbjct: 752 PIILPSLPD-VEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQNRTK 797 >SB_29692| Best HMM Match : ig (HMM E-Value=5.4e-12) Length = 567 Score = 39.9 bits (89), Expect = 0.049 Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 13/102 (12%) Query: 56 GDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKL----RGNPTPVVSWTRKKAP 111 G + PI G GEP PP+ + N + L GNP PVV+W R+ Sbjct: 263 GPKGPI--GPKGEPGPPLTKPKITTGSPKSRANVSTKAWLPCVASGNPHPVVTWQRRNGS 320 Query: 112 LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 L + E +G L + + D+GEY C AR+ G Sbjct: 321 LPQRRSKV----EMSG---LSVSHVTTADQGEYGCEARSIMG 355 Score = 36.7 bits (81), Expect = 0.46 Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 17/156 (10%) Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472 C +G P+P VTW R+ + V SG L +++VT +D G C AR+ G Sbjct: 302 CVASGNPHPVVTW---QRRNGSLPQRRSKVEMSG---LSVSHVTTADQGEYGCEARSIMG 355 Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532 L I ++++ + + T + EP+V+ +A G WQ+ ++ Sbjct: 356 VEVVWTEL--IVQDRLRFTMKMPKQQTFYM--FEPIVVPCQAKG--AVGTIWQRKN-RMM 408 Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568 P + R +G TL +PRA D+ Y C N+ Sbjct: 409 PE-KARTLING---TLFLPRASPRDSGTYTCIVTNL 440 Score = 32.7 bits (71), Expect = 7.5 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYN-SAGRVTVAAKLKVTQPDQADNLPALTP 4726 + +RT TL + A P D G Y C+ N R+T + ++ V P ++ L P Sbjct: 410 EKARTLINGTLFLPRASPRDSGTYTCIVTNLLQRRITESVEISVLYPKSCHHIKQLRP 467 >SB_21223| Best HMM Match : I-set (HMM E-Value=2.8e-11) Length = 90 Score = 39.9 bits (89), Expect = 0.049 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 5/76 (6%) Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQ 562 G ++ + A G PTP +TWQK+G P P +RI + ++L I K DA YQ Sbjct: 14 GSVLLWHCTATGYPTPVLTWQKNGQGFNPWWPPHIRILAN---NSLLINGVKREDAGSYQ 70 Query: 563 CTAQNVAGSTATRARL 578 C A + S A +A L Sbjct: 71 CRATINSLSNAIQAVL 86 Score = 38.3 bits (85), Expect = 0.15 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 2/89 (2%) Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453 F + QD + G + + C TG P P +TW N + + I + N++L+I Sbjct: 2 FTRTPQDTAIDLGSVLLWHCTATGYPTPVLTWQKNGQGFNPWWPPHIRI--LANNSLLIN 59 Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNV 482 V D+G C A S A Q L V Sbjct: 60 GVKREDAGSYQCRATINSLSNAIQAVLIV 88 >SB_33134| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2208 Score = 39.9 bits (89), Expect = 0.049 Identities = 46/184 (25%), Positives = 88/184 (47%), Gaps = 21/184 (11%) Query: 4228 ETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQ-----SVKRKKNEEYYNKLQ 4282 ET+L+K E + + +LK +V KE ET+ Q S+ K +E K+ Sbjct: 994 ETKLKKAVNETKRYESSS-----SQLKQQV-KELETDNLQRKQKLSLTEKDRDELERKIA 1047 Query: 4283 ELENEQVIKESRLRESTHQYAIP-----GDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRV 4337 EL+ + E R R++TH+ A +++T+N AK+ + + Q + Q Sbjct: 1048 ELQ--AITSELRKRQATHEAANSKLSEDNERLTNNAAAKAQNIERDAIIQQLMDEKSQMS 1105 Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEV-VGDKEITRKITS-TETTEIEHKAQ 4395 +K +++ + ++ E ++ Q+ +KE+ KE+ KIT+ TE ++ + KA Sbjct: 1106 KKLQSKEDELATEKANSQKHTET-LSSQRAKEKELHTNIKELEAKITTLTEESQAKLKAS 1164 Query: 4396 TQER 4399 + E+ Sbjct: 1165 SYEK 1168 >SB_20290| Best HMM Match : ig (HMM E-Value=2.9e-15) Length = 978 Score = 39.9 bits (89), Expect = 0.049 Identities = 38/149 (25%), Positives = 67/149 (44%), Gaps = 13/149 (8%) Query: 1810 LESQHESALQKIQQLEDSSRYQRRED-VEVAVN-QAPRFITQLNGPTKLSEGQSAHYECR 1867 ++S+ KIQ ++ +Q + +E +N QAP + P+ ++E S C+ Sbjct: 103 IKSKDGFGAHKIQCRVTANSFQTGQPPLETLLNVQAPISKLSVIVPSAVNESDSVRMTCQ 162 Query: 1868 IEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927 E PDP W FN K + G ND + +L+V+ + G YTC A + G Sbjct: 163 AEGSPDPKPTFRW-FNAKGEEIG------NDTFYT---VLSVHRDRPGPYTCLATDACGH 212 Query: 1928 A-VSSIRLNVQSKESIIRDSQHESALEKI 1955 +++ L VQ K + ++ A + + Sbjct: 213 IHRANVTLTVQYKPDFTKLTKKSPAQDTV 241 Score = 33.9 bits (74), Expect = 3.2 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 11/102 (10%) Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885 V P ++ I V ES+ VR C+ E DPK W+ N K G+ T Y Sbjct: 136 VQAPISKLSVIVPSAVNESDSVRMTCQAEGSPDPKPTFRWF-NAKGEEIGN--DTFY--- 189 Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGE-DFTKATISCKKLPD 3926 +L V+ + G Y C A + G T++ + PD Sbjct: 190 ----TVLSVHRDRPGPYTCLATDACGHIHRANVTLTVQYKPD 227 >SB_24046| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2848 Score = 39.5 bits (88), Expect = 0.065 Identities = 43/217 (19%), Positives = 92/217 (42%), Gaps = 6/217 (2%) Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYY 4278 DE + + E E+ +E + LQR+ R E K ++ + E +Q ++R+K E Sbjct: 1478 DEERRLIMEQQERERR-QEMEYLQREKEERLRVEEALKKLEREKEEERQRLEREKELEIE 1536 Query: 4279 NKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQ 4338 +L +++ ++VI+ R R+ + +K + + + + ++ E ++ + Sbjct: 1537 RQL-KIKEKEVIRLQRERDEERRRREDEEKRIQMEKVEELKRIEREKEEELERQMREKEE 1595 Query: 4339 KKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE 4398 + QK D E + A++ + + E E + E E E + + +E Sbjct: 1596 EMERQKQVFQDTLEQERRLRNDREAEEARRRLEEASRSEEYERQRQLELQEKERRNKEEE 1655 Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFD 4435 + + + + K+ R+FE E AR E E + Sbjct: 1656 DNLLDAYRRKQEQLLEKE----RIFEEEMARRERELE 1688 >SB_33855| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 879 Score = 39.1 bits (87), Expect = 0.086 Identities = 30/132 (22%), Positives = 47/132 (35%), Gaps = 13/132 (9%) Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507 H L + + + TCV N++G+ ++ + ++ + + T+ EG Sbjct: 144 HGLFVLRLNTPGVTIFTCVPSNEAGDGLN--KIVTVTVKEFHSSVSIAPARTITTSEGSY 201 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 V + A I W KDGVP P TL P Y CT Sbjct: 202 VQMTCSASAVDLSSINWVKDGVPQAKGP-----------TLTFPSISRDQGGVYNCTVIE 250 Query: 568 VAGSTATRARLY 579 GS +T +Y Sbjct: 251 GCGSASTDIAVY 262 Score = 32.3 bits (70), Expect = 9.9 Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSRYKL 4159 P V P +TV E + C G P P W+ G+T+ +G Y + Sbjct: 12 PSSVVISPSCLTVTERDQVNLTCSADGTPPPTFTWISPQGHTVAHGPSYTI 62 >SB_18843| Best HMM Match : I-set (HMM E-Value=1e-07) Length = 339 Score = 39.1 bits (87), Expect = 0.086 Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 11/120 (9%) Query: 1821 IQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879 ++ ++ +SR Y + ++ + +AP F L+ ++E + C P PN V Sbjct: 227 VKIMDPTSRVYTALKAWDLTIREAPAFNPPLDRSRDVAEDKDFSITCSASGRPAPN--VT 284 Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQ 1937 W K S + T N A L +L + +G Y C+AIN++G+ + +NVQ Sbjct: 285 WV--NKTSGSPVAHGTGN----ATLSLLKIQRHQAGVYQCQAINDVGRGAITQDVTINVQ 338 Score = 39.1 bits (87), Expect = 0.086 Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 16/119 (13%) Query: 1691 LEDTSK-YQRHSAQDEVITQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR 1748 ++ TS+ Y A D I +AP F P+ R VAE++ F G P V W+ Sbjct: 230 MDPTSRVYTALKAWDLTIREAPAFNPPLDRSRDVAEDK--DFSITCSASGRPAPNVTWVN 287 Query: 1749 --NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQ 1803 +G P+ H G L++ + +G Y C+AIN++G A+T T+ VQ Sbjct: 288 KTSGSPVA--------HGTGNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDVTINVQ 338 Score = 37.5 bits (83), Expect = 0.26 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 7/77 (9%) Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458 + RDV E K C +GRP P VTW +N + + + +GN L + + Sbjct: 259 RSRDVAEDKDFSITCSASGRPAPNVTW-VNKT------SGSPVAHGTGNATLSLLKIQRH 311 Query: 459 DSGVVTCVARNKSGETA 475 +GV C A N G A Sbjct: 312 QAGVYQCQAINDVGRGA 328 Score = 36.3 bits (80), Expect = 0.61 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 15/128 (11%) Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVRE-DITVMQAPQFSRALHNIETV-EGTNVHLE 1331 DI T ++ + +++++ +R ++ D+T+ +AP F+ L V E + + Sbjct: 213 DIKRVTVQDERVYLVKIMDPTSRVYTALKAWDLTIREAPAFNPPLDRSRDVAEDKDFSIT 272 Query: 1332 CRLQPVGDQTMRVEWF--CNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN 1389 C G V W +G P+ A+ L LL + +GVY CQA N Sbjct: 273 CSAS--GRPAPNVTWVNKTSGSPV--------AHGTGNATLSLLKIQRHQAGVYQCQAIN 322 Query: 1390 QLGE-AVT 1396 +G A+T Sbjct: 323 DVGRGAIT 330 Score = 35.5 bits (78), Expect = 1.1 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 8/100 (8%) Query: 2635 DTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKST 2694 D +++AP F L + E + + R PN + W V T+G+ + Sbjct: 244 DLTIREAPAFNPPLDRSRDVAEDKDFSITCSASGRPAPN--VTW----VNKTSGSPV--A 295 Query: 2695 FDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 G TLS+ ++ +G+Y C+A N +G T + I Sbjct: 296 HGTGNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDVTI 335 Score = 34.3 bits (75), Expect = 2.5 Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 14/122 (11%) Query: 1955 IQYLEDDSRYKRAVQD-DSFVVEKPQFGKPI-KNAEVTEGHPVHLEATLTPVNDPTMRVE 2012 ++ ++ SR A++ D + E P F P+ ++ +V E + T + P V Sbjct: 227 VKIMDPTSRVYTALKAWDLTIREAPAFNPPLDRSRDVAEDKDFSI--TCSASGRPAPNVT 284 Query: 2013 WY--CNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 W +G PV G G L +L G Y C+A N VG T V ++ Sbjct: 285 WVNKTSGSPVAHGT--------GNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDVTIN 336 Query: 2071 AK 2072 + Sbjct: 337 VQ 338 Score = 33.1 bits (72), Expect = 5.7 Identities = 21/86 (24%), Positives = 35/86 (40%), Gaps = 8/86 (9%) Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432 R+ P F PL ++ E + C G P V W + +S H G Sbjct: 248 REAPAFNPPLDRSRDVAEDKDFSITCSAS--GRPAPNVTW------VNKTSGSPVAHGTG 299 Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458 ++++ ++ GVY C+A N +G Sbjct: 300 NATLSLLKIQRHQAGVYQCQAINDVG 325 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/91 (23%), Positives = 36/91 (39%), Gaps = 7/91 (7%) Query: 4623 PEIIEPL-KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681 P PL + + VAE + +C G+P P V W + + ++ TL Sbjct: 251 PAFNPPLDRSRDVAEDKDFSITCSASGRPAPNVTW------VNKTSGSPVAHGTGNATLS 304 Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 + + G Y+C A N GR + + + Sbjct: 305 LLKIQRHQAGVYQCQAINDVGRGAITQDVTI 335 >SB_11246| Best HMM Match : ig (HMM E-Value=7.5e-07) Length = 80 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 11/75 (14%) Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561 VR GE + L G PTP ++W K G H+ GG + A +D Y Sbjct: 6 VRAGETITLTCAVAGNPTPSVSWSKAGSG---------HSTGG-NVFTKAGATKADTGQY 55 Query: 562 QCTAQN-VAGSTATR 575 CTA N V G+ TR Sbjct: 56 VCTAVNIVTGNIQTR 70 >SB_1675| Best HMM Match : ig (HMM E-Value=5.6e-05) Length = 964 Score = 38.7 bits (86), Expect = 0.11 Identities = 26/62 (41%), Positives = 32/62 (51%), Gaps = 9/62 (14%) Query: 2672 PNLKIEWFKN-GVTL--TTGARLKSTFDFGL----VT--LSINSLRNDDSGIYTCKATNL 2722 P LKI W+KN G+ + T G K TFD VT L+I L N DSG+Y C + Sbjct: 239 PGLKINWYKNTGLLIPGTEGVSWKITFDTDFDENRVTSKLNIAKLNNTDSGLYQCNVSTK 298 Query: 2723 LG 2724 G Sbjct: 299 FG 300 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 9/62 (14%) Query: 2941 PDLKIEWYFNGKVL---EQGSRFKLTSDFGF----VT--LDLVDVYERDSGIYTCKAYNK 2991 P LKI WY N +L +G +K+T D F VT L++ + DSG+Y C K Sbjct: 239 PGLKINWYKNTGLLIPGTEGVSWKITFDTDFDENRVTSKLNIAKLNNTDSGLYQCNVSTK 298 Query: 2992 RG 2993 G Sbjct: 299 FG 300 >SB_43870| Best HMM Match : Pkinase_Tyr (HMM E-Value=0) Length = 869 Score = 38.7 bits (86), Expect = 0.11 Identities = 25/77 (32%), Positives = 31/77 (40%), Gaps = 4/77 (5%) Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695 EG E C G P P + WYK D L P Q +Y L I P+ G Y C Sbjct: 47 EGSKAELICDATGYPQPVIAWYK-DGLHYPG---QPKLGPFDYRLTIQGLNPDSAGKYMC 102 Query: 4696 VAYNSAGRVTVAAKLKV 4712 N+ G + +KV Sbjct: 103 NVTNAFGWESYTYSIKV 119 Score = 37.9 bits (84), Expect = 0.20 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P I W+K+G+ +L FD+ L+I L D +G Y C TN G T S Sbjct: 61 PQPVIAWYKDGLHYPGQPKL-GPFDY---RLTIQGLNPDSAGKYMCNVTNAFGWESYTYS 116 Query: 2732 IKIE 2735 IK+E Sbjct: 117 IKVE 120 Score = 33.5 bits (73), Expect = 4.3 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 4/56 (7%) Query: 252 ISTEIDRSLGPVSPPKIAQKPRNS----KLQEGADAQFQVQLSGNPRPRVTWFKNG 303 ++ + +LG PP+ + + K QEG+ A+ +G P+P + W+K+G Sbjct: 16 LTLSVGLTLGNTEPPQFKDLSKMNDIQRKYQEGSKAELICDATGYPQPVIAWYKDG 71 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 10/91 (10%) Query: 67 GEPSPPIFEQIFK----NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRY 122 G PP F+ + K ++ +G A+ G P PV++W + + Y + Sbjct: 25 GNTEPPQFKDLSKMNDIQRKYQEGSKAELICDATGYPQPVIAWYK------DGLHYPGQP 78 Query: 123 NEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153 D L I+ + P G+Y C N +G Sbjct: 79 KLGPFDYRLTIQGLNPDSAGKYMCNVTNAFG 109 >SB_35812| Best HMM Match : Atrophin-1 (HMM E-Value=0.23) Length = 4240 Score = 38.7 bits (86), Expect = 0.11 Identities = 36/156 (23%), Positives = 71/156 (45%), Gaps = 13/156 (8%) Query: 4259 KEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSM 4318 K P+ + Q+ + K + + K +E++ ++ S + + +P DK T++T+A+ Sbjct: 2568 KPPQEKTQERLNSKADTKKGLK-EEIKTTPIVSSSGQAKKNERKVLPKDKPTNDTLAEKK 2626 Query: 4319 AQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHV-AKQKQTQ----KEVV 4373 + ED +++ E E R + ++ PDP+ GK+ K TQ + VV Sbjct: 2627 VSKPEDTVEKKSE--EGRFSRFISSMLSEPDPAHP---GKDKEQDKKDDSTQVLPARMVV 2681 Query: 4374 GDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSK 4409 D++ K T+ T + + + EG KP + Sbjct: 2682 QDEKKEAKKTAENTW--KKNVSNPKTIPEGEHKPEE 2715 >SB_23775| Best HMM Match : Tropomyosin (HMM E-Value=0) Length = 442 Score = 38.7 bits (86), Expect = 0.11 Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 8/125 (6%) Query: 4222 TQYQRTETELEKTFEER--QVLQRQGVIDHRP------ELKPKVIKEPETEWQQSVKRKK 4273 TQ Q TE E + ER +VL+ +G D + + + E E Q ++ Sbjct: 67 TQGQLTEAEKQADESERARKVLENRGASDEERLASLERQYNDALERTEEAEKQYEEISER 126 Query: 4274 NEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVT 4333 +E N+L+E E + E+R++E + + G+ + S +++ A ED + Sbjct: 127 LQELENELEEAEQKADAAEARVKELEEEVTLVGNNLRSLEISEGKASEREDTYENQIREL 186 Query: 4334 EQRVQ 4338 E ++Q Sbjct: 187 ETKLQ 191 Score = 36.3 bits (80), Expect = 0.61 Identities = 33/148 (22%), Positives = 67/148 (45%), Gaps = 9/148 (6%) Query: 4259 KEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSM 4318 K +T+ Q + K+ +E + LEN E RL QY D + A+ Sbjct: 63 KLADTQGQLTEAEKQADESERARKVLENRGASDEERLASLERQY---NDALERTEEAEKQ 119 Query: 4319 AQRYEDNLDQTEEVTEQRVQKKVTQKPRIPD-PSESTVHG---KEVHVAKQKQTQKEVVG 4374 + + L + E E+ QK + R+ + E T+ G + + +++ K +++E Sbjct: 120 YEEISERLQELENELEEAEQKADAAEARVKELEEEVTLVGNNLRSLEISEGKASEREDTY 179 Query: 4375 DKEITRKITSTETTEIEHKAQTQERVVE 4402 + +I R++ T+ + E +A+ E+ V+ Sbjct: 180 ENQI-REL-ETKLQDAEERAEKAEQKVQ 205 >SB_23345| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 903 Score = 38.3 bits (85), Expect = 0.15 Identities = 38/131 (29%), Positives = 68/131 (51%), Gaps = 17/131 (12%) Query: 4218 YDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELK----PKVIKEPETEWQQSVK--- 4270 YD++ + +R + E+ +ER+ +R PE K PKV+ EP E + +VK Sbjct: 519 YDDSWRGRRARRKAEEERKERERRERLEKKHSEPEKKTEEPPKVVVEPTVEKEPAVKVES 578 Query: 4271 RKKNEEYYN---KLQELENEQVIK----ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYE 4323 K EE + K ++ E+ K +RLRE+T + + GDK S++ +S ++R+E Sbjct: 579 EKTEEEPLDDEAKREKARQERAAKRAERRARLREATSEES--GDKGQSDSSDRS-SRRHE 635 Query: 4324 DNLDQTEEVTE 4334 ++ + + TE Sbjct: 636 ESDTSSSKDTE 646 Score = 35.9 bits (79), Expect = 0.80 Identities = 29/126 (23%), Positives = 55/126 (43%), Gaps = 4/126 (3%) Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYY 4278 +E + QR E E ++ +E + +++ H+ E + K + + W+ R+K EE Sbjct: 477 EEEERKQREEEERKQKEKEEEKKRKEEERKHKEEEEKKTEESYDDSWRGRRARRKAEE-E 535 Query: 4279 NKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQ 4338 K +E K S + T + P V TV K A + E + E + ++ + Sbjct: 536 RKERERRERLEKKHSEPEKKTEE---PPKVVVEPTVEKEPAVKVESEKTEEEPLDDEAKR 592 Query: 4339 KKVTQK 4344 +K Q+ Sbjct: 593 EKARQE 598 >SB_50677| Best HMM Match : I-set (HMM E-Value=6.7e-11) Length = 87 Score = 38.3 bits (85), Expect = 0.15 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 11/86 (12%) Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550 P + +R GE + L G PTP ++W K G G + + Sbjct: 2 PPGITPIQNTTIRAGETITLTCAVAGNPTPSVSWSKAG----------SGQSTGGNVFNE 51 Query: 551 PRAKASDAAWYQCTAQN-VAGSTATR 575 A +D Y CTA N V+G+T T+ Sbjct: 52 AGATKADTGQYVCTAVNIVSGNTQTK 77 Score = 34.7 bits (76), Expect = 1.9 Identities = 12/36 (33%), Positives = 20/36 (55%) Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658 P I P+++ + G+ I +C + G P P+V W K Sbjct: 2 PPGITPIQNTTIRAGETITLTCAVAGNPTPSVSWSK 37 Score = 32.3 bits (70), Expect = 9.9 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 13/80 (16%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 P + P+ N + G+ I L C + G+PT V W G + G + + G Sbjct: 2 PPGITPIQNTT-IRAGETITLTCAVA--GNPTPSVSWSKAGSGQSTGGN--VFNEAG--- 53 Query: 1237 LDIIHATSADTGEYTVRAVN 1256 AT ADTG+Y AVN Sbjct: 54 -----ATKADTGQYVCTAVN 68 >SB_40656| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 492 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%) Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP-QDSGKYEC 4586 G+ V +V+G +P + ++ G KV + + +E G Y +LI++ +D GKY C Sbjct: 217 GERVTRVCQVSG-EPFEGWYDPQGNKVTAQVDHVYVERRGPYHVLIIDGVTAEDGGKYTC 275 Query: 4587 VAINSAGEARCDAECVVSLPAT 4608 + + + CV P T Sbjct: 276 RGSFDSAQVGINVNCVSGTPKT 297 Score = 34.3 bits (75), Expect = 2.5 Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336 + EG + G+P P+ W KNGQ + ++ ++ +L ++ SDSG Y Sbjct: 12 MAEGTTGIIFTTVRGHPPPKYIWTKNGQPINLADDRYTVSPSG--SLSIKGVTSSDSGEY 69 Query: 337 TL 338 +L Sbjct: 70 SL 71 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 4/76 (5%) Query: 84 AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143 A+G +RG+P P WT+ P+ N RY SL IK + D GE Sbjct: 13 AEGTTGIIFTTVRGHPPPKYIWTKNGQPI---NLADDRYTVSPSG-SLSIKGVTSSDSGE 68 Query: 144 YTCTARNQYGEAICSV 159 Y+ R Q + Sbjct: 69 YSLNVRQQLASGFMKI 84 >SB_26233| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 463 Score = 37.9 bits (84), Expect = 0.20 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI 4382 E + D+ EE E++ +KK+TQK + P + G + +KQ+ E D + K+ Sbjct: 205 ESDDDEEEEEEEEKEEKKLTQKKKGKTPEQKKTPGTKKAASKQRHPTDEKRKDGQ--EKV 262 Query: 4383 TSTETTEIEHKAQTQE 4398 E E+E T+E Sbjct: 263 EEKEKGEVEDAQTTEE 278 >SB_16822| Best HMM Match : I-set (HMM E-Value=1.3e-07) Length = 259 Score = 37.9 bits (84), Expect = 0.20 Identities = 37/120 (30%), Positives = 55/120 (45%), Gaps = 16/120 (13%) Query: 1691 LEDTS-KYQRHSAQDEVITQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR 1748 ++ TS KY A + I AP F P+ R VAE++ F G P V W+ Sbjct: 104 MDPTSYKYTALRAWNLTIRAAPAFNQPLDRSRDVAEDK--DFSITCSASGRPAPNVTWVN 161 Query: 1749 --NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINEL-GEAVTSS-TLFVQS 1804 +G P+ H G L++ + +G Y C+AIN++ EA+T T+ VQS Sbjct: 162 KTSGSPVA--------HGTGSATLSLLKIQRHQAGVYQCQAINDVRREAITQDVTINVQS 213 Score = 34.7 bits (76), Expect = 1.9 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 10/114 (8%) Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886 S +Y + + AP F L+ ++E + C P PN V W K Sbjct: 108 SYKYTALRAWNLTIRAAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPN--VTWV--NKT 163 Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL-GQAVS-SIRLNVQS 1938 S + T G A L +L + +G Y C+AIN++ +A++ + +NVQS Sbjct: 164 SGSPVAHGT----GSATLSLLKIQRHQAGVYQCQAINDVRREAITQDVTINVQS 213 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/103 (24%), Positives = 43/103 (41%), Gaps = 8/103 (7%) Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697 ++ AP F L + E + + R PN + W V T+G+ + Sbjct: 121 IRAAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPN--VTW----VNKTSGSPV--AHGT 172 Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL 2740 G TLS+ ++ +G+Y C+A N + T + I + WL Sbjct: 173 GSATLSLLKIQRHQAGVYQCQAINDVRREAITQDVTINVQSWL 215 Score = 33.9 bits (74), Expect = 3.2 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449 AP F + + + RDV E K C +GRP P VTW +N + + + +G+ Sbjct: 124 APAFNQPLDRSRDVAEDKDFSITCSASGRPAPNVTW-VNKT------SGSPVAHGTGSAT 176 Query: 450 LMITNVTLSDSGVVTCVARN 469 L + + +GV C A N Sbjct: 177 LSLLKIQRHQAGVYQCQAIN 196 Score = 33.1 bits (72), Expect = 5.7 Identities = 21/83 (25%), Positives = 33/83 (39%), Gaps = 8/83 (9%) Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432 R P F QPL ++ E + C G P V W + +S H G Sbjct: 122 RAAPAFNQPLDRSRDVAEDKDFSITCSAS--GRPAPNVTW------VNKTSGSPVAHGTG 173 Query: 2433 YVSMTISHVRDEDEGVYMCRASN 2455 ++++ ++ GVY C+A N Sbjct: 174 SATLSLLKIQRHQAGVYQCQAIN 196 >SB_1246| Best HMM Match : Mito_carr (HMM E-Value=1.4013e-45) Length = 773 Score = 37.9 bits (84), Expect = 0.20 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 3/94 (3%) Query: 4224 YQRTETELEKTFEERQVLQRQGVIDHRPE-LKPKVIKEPET--EWQQSVKRKKNEEYYNK 4280 Y+R L KT E+ Q Q++ + H P +P P T + QQ ++++ ++ + Sbjct: 363 YRRNRRHLRKTREQMQPPQKEDIEMHCPSPSRPAKPAMPTTHKQQQQQQQQQQQQQQQQQ 422 Query: 4281 LQELENEQVIKESRLRESTHQYAIPGDKVTSNTV 4314 Q+ + +Q ++ + ++ Q P +K NTV Sbjct: 423 QQQQQQQQQQQQQQQQQQQQQEKQPSEKAPENTV 456 >SB_38167| Best HMM Match : Collagen (HMM E-Value=7e-12) Length = 299 Score = 37.9 bits (84), Expect = 0.20 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 5/101 (4%) Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615 N P +P +L ++ ++SA C +I D + V W G L G+R + G V Sbjct: 204 NAPRAEISPRELNVNASASAQLNCSIIS-GDPNAVVSWKRIGGDL-PGNRSRDDGRGGLV 261 Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGII 3656 I + V DAG+Y C + G + + V G++ I+ Sbjct: 262 IRD---VRSSDAGMYECASAGGLGRSRDVALVSVNGKRQIM 299 Score = 35.5 bits (78), Expect = 1.1 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 5/72 (6%) Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446 N+ +A +C +I GDP V W K I ++ D G + I VR D Sbjct: 216 NVNASASAQLNCSIIS-GDPNAVVSW----KRIGGDLPGNRSRDDGRGGLVIRDVRSSDA 270 Query: 2447 GVYMCRASNLLG 2458 G+Y C ++ LG Sbjct: 271 GMYECASAGGLG 282 Score = 35.1 bits (77), Expect = 1.4 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 4/71 (5%) Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370 DP+ V W G LP G+R R G+VI D+ ++G YEC + LGR A Sbjct: 233 DPNAVVSWKRIGGDLP-GNRSRDDGRGGLVIRDVR---SSDAGMYECASAGGLGRSRDVA 288 Query: 3371 NLKCTSKENLI 3381 + K ++ Sbjct: 289 LVSVNGKRQIM 299 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 4/71 (5%) Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508 DPN V W G L G+R R G VI ++ + D+G Y C + G + A Sbjct: 233 DPNAVVSWKRIGGDLP-GNRSRDDGRGGLVIRDVRSS---DAGMYECASAGGLGRSRDVA 288 Query: 3509 SMKVQGKRNII 3519 + V GKR I+ Sbjct: 289 LVSVNGKRQIM 299 Score = 33.9 bits (74), Expect = 3.2 Identities = 36/121 (29%), Positives = 51/121 (42%), Gaps = 15/121 (12%) Query: 3800 PQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859 P+G G + + E GRI +AP+ E P+ + V S + C + DP Sbjct: 186 PKGDVGPRGLKGEPGRIRNAPRAE----ISPREL------NVNASASAQLNCSI-ISGDP 234 Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919 + W R G LP G+R R D G L I V + D+G Y C + G A + Sbjct: 235 NAVVSWKRIGGDLP-GNRSR---DDGRGGLVIRDVRSSDAGMYECASAGGLGRSRDVALV 290 Query: 3920 S 3920 S Sbjct: 291 S 291 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 5/102 (4%) Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766 I AP + +++ V + +A +I GDP V W R G + NR D G Sbjct: 202 IRNAPRAEISPRELNVNASASAQLNCSIIS-GDPNAVVSWKRIGGDLPG-NR---SRDDG 256 Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808 L ++ V D+G Y C + LG + + + V K + Sbjct: 257 RGGLVIRDVRSSDAGMYECASAGGLGRSRDVALVSVNGKRQI 298 Score = 33.9 bits (74), Expect = 3.2 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730 DPN + W + G L G R + GLV I +R+ D+G+Y C + LG + A Sbjct: 233 DPNAVVSWKRIGGDLP-GNRSRDDGRGGLV---IRDVRSSDAGMYECASAGGLGRSRDVA 288 Query: 2731 SIKIEDRHWLL 2741 + + + ++ Sbjct: 289 LVSVNGKRQIM 299 Score = 33.5 bits (73), Expect = 4.3 Identities = 19/83 (22%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573 P ++ + +NV + +L+ + P V + K++ D+ +DG L+I Sbjct: 206 PRAEISPRELNVNASASAQLNCSIISGDPNAVV---SWKRIGGDLPGNRSRDDGRGGLVI 262 Query: 4574 LEAYPQDSGKYECVAINSAGEAR 4596 + D+G YEC + G +R Sbjct: 263 RDVRSSDAGMYECASAGGLGRSR 285 Score = 33.5 bits (73), Expect = 4.3 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 1861 SAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920 SA C I DPN V W G L G+R S D G L I V D+G Y C Sbjct: 222 SAQLNCSIIS-GDPNAVVSWKRIGGDLP-GNR---SRDDGRGGLVIRDVRSSDAGMYECA 276 Query: 1921 AINNLGQAVSSIRLNVQSKESII 1943 + LG++ ++V K I+ Sbjct: 277 SAGGLGRSRDVALVSVNGKRQIM 299 Score = 33.1 bits (72), Expect = 5.7 Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 5/89 (5%) Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDS 2179 N+ A C + DP+ + W G + G+R R G V D+ + D+ Sbjct: 216 NVNASASAQLNCSIIS-GDPNAVVSWKRIGGDL-PGNRSRDDGRGGLVIRDVR---SSDA 270 Query: 2180 GTYMCKATNKLGEAVNTCTLKVAGHRNII 2208 G Y C + LG + + + V G R I+ Sbjct: 271 GMYECASAGGLGRSRDVALVSVNGKRQIM 299 >SB_47033| Best HMM Match : WAP (HMM E-Value=1.8e-38) Length = 667 Score = 37.5 bits (83), Expect = 0.26 Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 2/95 (2%) Query: 268 IAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRN 327 + +K L+ G +V + G P P+ W K+ Q L + L ++N Sbjct: 391 VEKKKSFQYLRPGEVGLIEVSIRGYPLPKSKWIKDNQPLNYRTGRYAVGKMGF--LGIKN 448 Query: 328 TQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362 Q+SD G Y+L+ +N V + PT +Y Sbjct: 449 VQRSDKGMYSLVLDNALEADVEVQVVQESCPTPTY 483 Score = 34.7 bits (76), Expect = 1.9 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 5/77 (6%) Query: 392 PQFVKVCQDRD-VTEGKMTRFDCRVTGRPYPEVTWFI-NDRQIRDDYNHKILVNESGNH- 448 PQ RD + G+ R C V +P+ V WF N ++I + ++ V + G + Sbjct: 578 PQVKAFSPGRDRLNTGEAVRRVCLVYRQPF--VGWFASNGQKIMSSRDERMFVEDHGIYK 635 Query: 449 ALMITNVTLSDSGVVTC 465 L+I NVT+ D+G C Sbjct: 636 VLVIRNVTVEDAGTYEC 652 >SB_57573| Best HMM Match : 7tm_2 (HMM E-Value=3.7e-40) Length = 956 Score = 37.5 bits (83), Expect = 0.26 Identities = 32/143 (22%), Positives = 62/143 (43%), Gaps = 7/143 (4%) Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRL-RESTHQYAIPGDKVTSNTVAKSMAQRYED 4324 ++ +KR K+++YY K + + QVI+ ++ RE T + P ++ S +R E Sbjct: 701 KKEIKRAKDKDYYEKNRNKKIAQVIERRKVCREETIGKSRPRTEIRK---VASTKRRKEQ 757 Query: 4325 NLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITRK 4381 EE+ +R ++K ++ R G+E + + + K K +T K Sbjct: 758 RATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKILQNTGERFKNRTSKKRVTDK 817 Query: 4382 ITSTETTEIEHKAQTQERVVEGP 4404 + E KA+ E ++ P Sbjct: 818 VKDKLPQTPEKKAEVLETLINSP 840 >SB_50620| Best HMM Match : Lectin_C (HMM E-Value=2.1e-14) Length = 620 Score = 37.5 bits (83), Expect = 0.26 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 4/54 (7%) Query: 4110 PPVFVSLPDA---VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160 PP VS P+ +TV G C TG P+P + WL NG + +G+ K+T Sbjct: 136 PPDIVS-PNGLVYITVAYGTMVNQSCVTTGLPRPEIQWLANGKQLRDGNDVKVT 188 Score = 36.7 bits (81), Expect = 0.46 Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440 V G M C TG P PE+ W N +Q+RD + K+ Sbjct: 150 VAYGTMVNQSCVTTGLPRPEIQWLANGKQLRDGNDVKV 187 Score = 33.1 bits (72), Expect = 5.7 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 7/83 (8%) Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP--DIRNKILEEDGTYTLLILEAYPQD 4580 + V G +V TG ++ WL NGK+++ D++ +L TL +L+ Sbjct: 148 ITVAYGTMVNQSCVTTGLPRPEIQWLANGKQLRDGNDVKVTLLPYMANVTLKVLK----- 202 Query: 4581 SGKYECVAINSAGEARCDAECVV 4603 + + +C +IN G A+ +V Sbjct: 203 NTELQCQSINRGGVAKASVMYIV 225 Score = 32.3 bits (70), Expect = 9.9 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 4622 PPEIIEP--LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664 PP+I+ P L VA G + SC G P P +QW K ++ Sbjct: 136 PPDIVSPNGLVYITVAYGTMVNQSCVTTGLPRPEIQWLANGKQLR 180 >SB_44087| Best HMM Match : I-set (HMM E-Value=1.5e-05) Length = 267 Score = 37.5 bits (83), Expect = 0.26 Identities = 24/83 (28%), Positives = 31/83 (37%), Gaps = 9/83 (10%) Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687 P I G ++ C + GKP P + W SK + +RI Sbjct: 188 PTNHTIAKIGSSVSLECDVKGKPPPNITW---------SKLGDNQWRSKGSVIRIFNFTV 238 Query: 4688 EDEGDYKCVAYNSAGRVTVAAKL 4710 ED G Y+C AYN G A L Sbjct: 239 EDRGIYECSAYNGIGPNVTAVSL 261 >SB_12530| Best HMM Match : I-set (HMM E-Value=3e-05) Length = 127 Score = 37.5 bits (83), Expect = 0.26 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 8/88 (9%) Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684 II +D+ EG + C + G P+P+V W K + Q+ T+ +Y R+S Sbjct: 5 IINASRDQNAIEGDPLTPICDVDGYPVPSVVWSKTPDSV------QLPATSPQY--RVSA 56 Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 D Y C A N G + + K+ V Sbjct: 57 VRSADARIYTCFASNEMGNASASMKVVV 84 >SB_11355| Best HMM Match : I-set (HMM E-Value=1.5e-05) Length = 288 Score = 37.5 bits (83), Expect = 0.26 Identities = 24/83 (28%), Positives = 31/83 (37%), Gaps = 9/83 (10%) Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687 P I G ++ C + GKP P + W SK + +RI Sbjct: 144 PTNHTIAKIGSSVSLECDVKGKPPPNITW---------SKLGDNQWRSKGSVIRIFNFTV 194 Query: 4688 EDEGDYKCVAYNSAGRVTVAAKL 4710 ED G Y+C AYN G A L Sbjct: 195 EDRGIYECSAYNGIGPNVTAVSL 217 Score = 32.3 bits (70), Expect = 9.9 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 12/121 (9%) Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892 + DV + P ++ T G S EC ++ P PN + W G ++ Sbjct: 127 QNDVSFRSFRKPNLLSYPTNHTIAKIGSSVSLECDVKGKPPPN--ITWSKLGD-----NQ 179 Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952 +R+ + + I ED G Y C A N +G V+++ L VQ R ++ E + Sbjct: 180 WRSKG----SVIRIFNFTVEDRGIYECSAYNGIGPNVTAVSL-VQYTGCTSRCAKKEVGV 234 Query: 1953 E 1953 E Sbjct: 235 E 235 >SB_7591| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 3261 Score = 37.5 bits (83), Expect = 0.26 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 6/74 (8%) Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564 G+P +L G+P I W KD P +P+ H +TL I +A D Y+C Sbjct: 3073 GKPGLLTCLFDGSPRS-IVWSKDDSPSLPS-----HMTANGNTLTISSVQAQDQGSYECM 3126 Query: 565 AQNVAGSTATRARL 578 A + S A + L Sbjct: 3127 ATDEFNSVAAKVSL 3140 Score = 35.1 bits (77), Expect = 1.4 Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 7/87 (8%) Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702 +C G P V W K D PS TA+ TL IS +D+G Y+C+A + Sbjct: 3079 TCLFDGSPRSIV-WSKDDSPSLPSHM-----TANGNTLTISSVQAQDQGSYECMATDEFN 3132 Query: 4703 RVTVAAKLKVTQ-PDQADNLPALTPLR 4728 V L++ P LPA LR Sbjct: 3133 SVAAKVSLRILGIPVLGRGLPARCLLR 3159 >SB_48288| Best HMM Match : ig (HMM E-Value=6.9e-08) Length = 234 Score = 37.1 bits (82), Expect = 0.35 Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 5/62 (8%) Query: 940 TLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999 T + W K G S ITT + I SV DAG YTC A N IG + + ++ Sbjct: 4 TPNITWTKQGVSAALRSNITT-----EIIHQIASVQKSDAGRYTCAANNEIGAVSRTLSV 58 Query: 1000 TI 1001 T+ Sbjct: 59 TV 60 Score = 37.1 bits (82), Expect = 0.35 Identities = 16/38 (42%), Positives = 21/38 (55%) Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551 PS T N+ VT G LV L +G+ P++V W K G Sbjct: 150 PSITFITANMTVTEGSLVNLQCNTSGSLPLNVSWSKVG 187 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%) Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731 P I W K GV+ A L+S ++ I S++ D+G YTC A N +G T S Sbjct: 3 PTPNITWTKQGVS----AALRSNITTEIIH-QIASVQKSDAGRYTCAANNEIGAVSRTLS 57 Query: 2732 IKI 2734 + + Sbjct: 58 VTV 60 Score = 34.7 bits (76), Expect = 1.9 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 5/55 (9%) Query: 293 PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347 P P +TW K G +++ ITT ++ + QKSD+G YT A N G + Sbjct: 3 PTPNITWTKQG---VSAALRSNITTE--IIHQIASVQKSDAGRYTCAANNEIGAV 52 Score = 33.9 bits (74), Expect = 3.2 Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 5/66 (7%) Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784 PT I W G A S + T I I + DAG YTC A N+ G+ + T Sbjct: 3 PTPNITWTKQGVSAALRSNITTE-----IIHQIASVQKSDAGRYTCAANNEIGAVSRTLS 57 Query: 3785 ITCSAK 3790 +T K Sbjct: 58 VTVHYK 63 Score = 32.3 bits (70), Expect = 9.9 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 6/79 (7%) Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799 P + W + GV + +TT + + V D+G YTC A NE+G + + Sbjct: 3 PTPNITWTKQGVSAALRSNITTE-----IIHQIASVQKSDAGRYTCAANNEIGAVSRTLS 57 Query: 1800 LFVQSK-ASLQLESQHESA 1817 + V K + QL + SA Sbjct: 58 VTVHYKPINTQLATTKTSA 76 Score = 32.3 bits (70), Expect = 9.9 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 5/63 (7%) Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859 PT + W K G S IT+ + I ++ DAG YT A N++G T S Sbjct: 3 PTPNITWTKQGVSAALRSNITT-----EIIHQIASVQKSDAGRYTCAANNEIGAVSRTLS 57 Query: 860 IRV 862 + V Sbjct: 58 VTV 60 >SB_50351| Best HMM Match : I-set (HMM E-Value=0.00016) Length = 419 Score = 37.1 bits (82), Expect = 0.35 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 1603 PVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAV 1662 P + L WYHN P+ R + T+N + D+M D+G Y A N+ G++ Sbjct: 14 PRARGALTYTWYHNAVPVSPDHRVSVTSNGSLLIKDVMR---PDNGIYQVFAENSFGKSS 70 Query: 1663 TSGIAIVHSKKS 1674 + ++ S+K+ Sbjct: 71 AEPVYLLVSEKT 82 >SB_24929| Best HMM Match : ig (HMM E-Value=8.2e-06) Length = 186 Score = 37.1 bits (82), Expect = 0.35 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 10/107 (9%) Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892 +E + V +AP LNG ++E C P PN V W K S Sbjct: 87 KEILRVVSTEAPALNPPLNGSHDVAEDTDFSITCSASGRPAPN--VTWV--NKTSGSPVA 142 Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ--AVSSIRLNVQ 1937 + T G A L +L + +G Y C+AIN++ + + + +NVQ Sbjct: 143 HGT----GSATLSLLKIQRHQAGVYQCQAINDVRREAIIQDVTINVQ 185 >SB_21954| Best HMM Match : V-set (HMM E-Value=0.011) Length = 291 Score = 37.1 bits (82), Expect = 0.35 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 11/91 (12%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 PP T+ Q+ N+T + +V G +P+ V WLK +V R + E L+ Sbjct: 157 PPLITIPIQSPNLTV-----IGIEVKGLRPVQVRWLKGDMEVDGQQRRFYINE--AMDLV 209 Query: 4573 ILEAYP-QDSGKYECVAINSAGEARCDAECV 4602 + Y DSG YE +A N C C+ Sbjct: 210 LSPPYSLSDSGSYEVMACNLVA---CVVRCI 237 Score = 33.1 bits (72), Expect = 5.7 Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 19/154 (12%) Query: 4553 KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC--DAECVVSLPATKD 4610 +V PD + +I + G + +L L P DSG Y C ++ G + AE VV A D Sbjct: 87 EVLPD-KTRIAKIGGVFHILDLS--PLDSGTYSCKGLDEKGVQKTIEIAELVVKRHAA-D 142 Query: 4611 KPKPQTK---AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK-PS 4666 K P +K PP I P++ ++ G V+W KGD + Sbjct: 143 KIPPGSKPYIKFKTPPLITIPIQSP-----NLTVIGIEVKGLRPVQVRWLKGDMEVDGQQ 197 Query: 4667 KYFQMSRTADEYTLRISEAFP-EDEGDYKCVAYN 4699 + F ++ D L +S + D G Y+ +A N Sbjct: 198 RRFYINEAMD---LVLSPPYSLSDSGSYEVMACN 228 >SB_11731| Best HMM Match : ig (HMM E-Value=1e-06) Length = 220 Score = 37.1 bits (82), Expect = 0.35 Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 31/177 (17%) Query: 406 GKMTRFDCRVTGRPYPEVTW-FINDRQIRDDYN---HKILVNESGNHALMITNVTLSDSG 461 G C G P + ++++ IR + N H IL++ G H ++T V ++D+G Sbjct: 20 GAAISLTCSAVGEPQLIIYHLYMDNLLIRKNINGMFHNILLDSVGIH--LLTCVPINDAG 77 Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521 V N+S +NV EK ++ +T+N EG VV A+G + + Sbjct: 78 V----GENRS------VSMNVTEKLPTIS--ITPLRATVN--EGSVVVFTCLAIGFQSFK 123 Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578 W+KDGV G S+L + D Y C + G+T A L Sbjct: 124 NFWKKDGV-----------FKGDGSSLTLSSVGTDDRGNYTCNVTSTCGTTMKTASL 169 Score = 33.9 bits (74), Expect = 3.2 Identities = 13/34 (38%), Positives = 22/34 (64%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +L+++S+ DD G YTC T+ G + TAS+ + Sbjct: 138 SLTLSSVGTDDRGNYTCNVTSTCGTTMKTASLDV 171 Score = 32.3 bits (70), Expect = 9.9 Identities = 13/39 (33%), Positives = 22/39 (56%) Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006 +LT+ SV D G+YTC + G +A+L ++ K + Sbjct: 138 SLTLSSVGTDDRGNYTCNVTSTCGTTMKTASLDVIYKPE 176 >SB_43527| Best HMM Match : Trypsin (HMM E-Value=0) Length = 366 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 3/61 (4%) Query: 296 RVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLA 354 RV WFKNG + + S H + H V + SD G YT A P I S YL+ Sbjct: 6 RVKWFKNGIEIPSLSEGHYFTASEGHLVFLVAHY--SDRGMYTCKATTPAATIEASAYLS 63 Query: 355 V 355 V Sbjct: 64 V 64 Score = 36.7 bits (81), Expect = 0.46 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811 ++W + G IP + ++ + Y D G +TC+ATT A +E SA L V+ Sbjct: 7 VKWFKNGIEIPSLSEGHYFTASEGHLVFLVAHYS-DRGMYTCKATTPAATIEASAYLSVR 65 Score = 35.5 bits (78), Expect = 1.1 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 5/64 (7%) Query: 3590 RVEWFHNGK--PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647 RV+WF NG P L+ T ++ V L + D G+YTCKAT S L Sbjct: 6 RVKWFKNGIEIPSLSEGHYFTASEGHLVFLV---AHYSDRGMYTCKATTPAATIEASAYL 62 Query: 3648 QVKG 3651 V+G Sbjct: 63 SVRG 66 Score = 32.3 bits (70), Expect = 9.9 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 5/63 (7%) Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE--DSGIYTCRAVNLVGTDEVSCRL 1534 +V+WFKNG + H F ++ L+A D G+YTC+A T E S L Sbjct: 6 RVKWFKNGIEIP---SLSEGHYFTASEGHLVFLVAHYSDRGMYTCKATTPAATIEASAYL 62 Query: 1535 TCR 1537 + R Sbjct: 63 SVR 65 Score = 32.3 bits (70), Expect = 9.9 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 1/60 (1%) Query: 669 KIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 +++W KNG I + S F L L + D G YTC+A + E A L V Sbjct: 6 RVKWFKNGIEIPSLSE-GHYFTASEGHLVFLVAHYSDRGMYTCKATTPAATIEASAYLSV 64 >SB_30644| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1887 Score = 36.7 bits (81), Expect = 0.46 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 2/66 (3%) Query: 798 SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857 S P + WYK GRP+ S S+ G SL I +R+ D G YT++A + Sbjct: 16 SYPLSKFVWYKRGRPLDMDSGRFSVSPSG--SLGIRRVRSVDVGIYTLKAQGGDEGVVQD 73 Query: 858 ASIRVA 863 I VA Sbjct: 74 TGISVA 79 >SB_29861| Best HMM Match : RRM_1 (HMM E-Value=1.10002e-42) Length = 1531 Score = 36.7 bits (81), Expect = 0.46 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 15/164 (9%) Query: 4248 DHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTH-----QY 4302 DH+P ++PE ++ R++ NK EL E+ K+ + ++S + Sbjct: 580 DHKPSQHQDYPEKPEHSIPKAENRERMPSVENK-SELAEERKGKKKKEKKSKRPLQPGEG 638 Query: 4303 AIPGDKVTSNTVAKSMAQRYEDNL----DQTEEVTEQRVQKKVTQKPRIPDPSESTVHGK 4358 G VAK + E+ D+T E+TE + P P+PS T K Sbjct: 639 GSRGSDTEEEVVAKRRKKVKEEERVTQPDKTSELTESTKRPAADAPPPTPEPSLPTEKKK 698 Query: 4359 EVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE 4402 K+K+ +KE +K+ R T E E K RV E Sbjct: 699 -----KEKREKKERKREKKTRRARTPVEEPENFEKDVPLPRVHE 737 >SB_17408| Best HMM Match : I-set (HMM E-Value=7.4e-06) Length = 136 Score = 36.7 bits (81), Expect = 0.46 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 2/75 (2%) Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794 G F +T KPT+QW+ G E F +E I N D G +TCR Sbjct: 19 GYNTSFTCIVTGFPKPTVQWINPGG--REVDTFDPRYEIIGDTFYIYNIESNDKGNWTCR 76 Query: 4795 ATTAAGQVETSAKLV 4809 T +E A ++ Sbjct: 77 VTGGDVTIEAVATII 91 Score = 36.3 bits (80), Expect = 0.61 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 16/97 (16%) Query: 265 PPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS--NKHEIITTHNH 320 PP+I Q+P K + G + F ++G P+P V W G R +++ ++EII Sbjct: 2 PPEIIQQPVPIKRYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEII----G 57 Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357 T + N + +D G++T C VT G + +E+ Sbjct: 58 DTFYIYNIESNDKGNWT--------CRVTGGDVTIEA 86 Score = 35.9 bits (79), Expect = 0.80 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 4110 PPVFVSLPDAVT--VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN--GSRYKLTYDGMY 4165 PP + P + V G F C VTG PKP V W+ G V+ RY++ D Y Sbjct: 2 PPEIIQQPVPIKRYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEIIGDTFY 61 Query: 4166 HFDI 4169 ++I Sbjct: 62 IYNI 65 Score = 35.5 bits (78), Expect = 1.1 Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 4/38 (10%) Query: 4622 PPEIIE---PLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656 PPEII+ P+K + V G F+C + G P PTVQW Sbjct: 2 PPEIIQQPVPIK-RYVTVGYNTSFTCIVTGFPKPTVQW 38 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 5/84 (5%) Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460 R VT G T F C VTG P P V W + D ++ + E I N+ +D Sbjct: 14 RYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRY---EIIGDTFYIYNIESNDK 70 Query: 461 GVVTCVARNKSGETAFQCRLNVIE 484 G TC R G+ + +I+ Sbjct: 71 GNWTC--RVTGGDVTIEAVATIID 92 >SB_53466| Best HMM Match : SCP (HMM E-Value=2.4e-27) Length = 5087 Score = 36.7 bits (81), Expect = 0.46 Identities = 33/162 (20%), Positives = 69/162 (42%), Gaps = 6/162 (3%) Query: 4219 DETTQ-YQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEY 4277 +ET + ++R EL +E + L++Q +D++ + + E E Q ++ K +E+ Sbjct: 4504 EETKESFERKSEELSAVTKECEALKKQ--LDNKSDQLSSLHDERELSLQNLQEQLKQKEF 4561 Query: 4278 Y--NKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQ 4335 + +E++ + E + Q D++ + QR ED + Q E E Sbjct: 4562 ELSSLKEEVDTTKQFAEQAANQMNEQQQEYEDQLRKMEMLYGELQRSEDTIHQLVEENEH 4621 Query: 4336 RVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKE 4377 + + + + E++ +EVH + KE D+E Sbjct: 4622 LRTVLDSHEDTVSEEGEASTSSEEVHY-HDESPAKEEASDEE 4662 >SB_48507| Best HMM Match : TolA (HMM E-Value=1) Length = 649 Score = 36.7 bits (81), Expect = 0.46 Identities = 53/236 (22%), Positives = 96/236 (40%), Gaps = 18/236 (7%) Query: 4198 KVIPRHDDYRGVLKNAPRPWYDETTQYQRTE------TELEKTFEERQVLQRQG------ 4245 K++ + RG P+ E T+++ TE TE +E++V++ +G Sbjct: 318 KIVDVEEGNRGGSVLEPKTKPTEATRHKPTEGVQPQPTEQGMVEDEKKVVEVEGGKGGGP 377 Query: 4246 VIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE--LENEQVIKESRLRESTHQYA 4303 + DH+ E + +P TE + V R ++ + +E+E+ + + Sbjct: 378 LPDHKTEPTDRTRPKP-TEPEAGVARDDIDDMKAAKRSGIVEDEKKVVDVEKGNRGGSLL 436 Query: 4304 IPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVA 4363 P + T T K + +Q E KV +I D E KE+ V Sbjct: 437 EPKTEPTEATRPKHSEGVHPQPTEQGVAEDENE-DLKVAVSGKIVDVEEGNEGNKELVVP 495 Query: 4364 KQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERV-VEGPVKPSKPPIFTKKMQ 4418 K + T++ V E T I + TT EH+ +T+E+ ++ P + P T +Q Sbjct: 496 KSR-TEELVYTTHEPTAPIETVTTTIKEHRLRTEEKTHLKSTTSPGQEPSTTSSVQ 550 >SB_11578| Best HMM Match : ig (HMM E-Value=3.3e-23) Length = 259 Score = 36.7 bits (81), Expect = 0.46 Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 19/138 (13%) Query: 437 NHKILVNESGNHALMITNVTLSDSG--VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494 N + N +G ++ N+ L+ SG V TCV N+ GE + ++ +V+ V Sbjct: 129 NQAVKTNTNG----VLNNIKLNTSGEHVFTCVPTNEIGEGLN--KTVIVNASEVLPVVSV 182 Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554 + + +G V L G +I+W KD + I G TL I + Sbjct: 183 DIPPNGRMVKGSSVTLTCNGTGPVPLQISWYKDNIFI-----------GSGKTLTISKVT 231 Query: 555 ASDAAWYQCTAQNVAGST 572 D Y C + G+T Sbjct: 232 VQDEGNYTCNVSSSCGTT 249 Score = 32.3 bits (70), Expect = 9.9 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSRY 4157 P V P + TV E + C G P P W+ G+T+V+G Y Sbjct: 3 PSSVVISPPSPTVTERDQVNLTCSADGTPPPTFTWISPQGHTVVHGPSY 51 >SB_3034| Best HMM Match : I-set (HMM E-Value=5e-09) Length = 84 Score = 36.7 bits (81), Expect = 0.46 Identities = 15/29 (51%), Positives = 20/29 (68%) Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKIT 3786 D + +AG YTC ATN+ GS TTT ++T Sbjct: 53 DSVTRSEAGTYTCTATNEMGSDTTTVQVT 81 Score = 32.7 bits (71), Expect = 7.5 Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 SVT +AG YTC A N +G TT+ +T+ Sbjct: 54 SVTRSEAGTYTCTATNEMGSDTTTVQVTV 82 >SB_56618| Best HMM Match : DUF1213 (HMM E-Value=0.022) Length = 1421 Score = 36.3 bits (80), Expect = 0.61 Identities = 20/112 (17%), Positives = 56/112 (50%), Gaps = 2/112 (1%) Query: 4262 ETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRE--STHQYAIPGDKVTSNTVAKSMA 4319 E + ++ K+K+ EE K +E+E ++ +E R +E + ++ D++ + Sbjct: 1182 EVQKKREEKKKREEEMREKEKEMEQNKIDQEKRKQELMESRRFQEEQDRLEEERRLEEER 1241 Query: 4320 QRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKE 4371 R + D+ + E+++++ + R+ + E +++ A++++ Q+E Sbjct: 1242 LRQLEEEDEQRRLEEEQIREAEEELRRLQEEREYREQMRKIAEARERKLQEE 1293 >SB_55200| Best HMM Match : E-MAP-115 (HMM E-Value=0.85) Length = 929 Score = 36.3 bits (80), Expect = 0.61 Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 9/144 (6%) Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK--SMAQRYE 4323 ++ +KR K+++YY K + + QVI+ + R + G T + K S +R E Sbjct: 15 KKEIKRAKDKDYYEKNRNKKIAQVIERRKARREETK----GKSRTRTEIKKAASKKRRKE 70 Query: 4324 DNLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITR 4380 EE+ +R ++K ++ R G+E + + + K K +T Sbjct: 71 QRATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKILQNTGERFKNRTSKKRVTD 130 Query: 4381 KITSTETTEIEHKAQTQERVVEGP 4404 K+ E KA+ E ++ P Sbjct: 131 KVKDKLPQTPEKKAEVLETLINSP 154 >SB_49614| Best HMM Match : E-MAP-115 (HMM E-Value=0.85) Length = 838 Score = 36.3 bits (80), Expect = 0.61 Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 9/144 (6%) Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK--SMAQRYE 4323 ++ +KR K+++YY K + + QVI+ + R + G T + K S +R E Sbjct: 15 KKEIKRAKDKDYYEKNRNKKIAQVIERRKARREETK----GKSRTRTEIKKAASKKRRKE 70 Query: 4324 DNLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITR 4380 EE+ +R ++K ++ R G+E + + + K K +T Sbjct: 71 QRATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKILQNTGERFKNRTSKKRVTD 130 Query: 4381 KITSTETTEIEHKAQTQERVVEGP 4404 K+ E KA+ E ++ P Sbjct: 131 KVKDKLPQTPEKKAEVLETLINSP 154 >SB_40579| Best HMM Match : E-MAP-115 (HMM E-Value=0.85) Length = 929 Score = 36.3 bits (80), Expect = 0.61 Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 9/144 (6%) Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK--SMAQRYE 4323 ++ +KR K+++YY K + + QVI+ + R + G T + K S +R E Sbjct: 15 KKEIKRAKDKDYYEKNRNKKIAQVIERRKARREETK----GKSRTRTEIKKAASKKRRKE 70 Query: 4324 DNLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITR 4380 EE+ +R ++K ++ R G+E + + + K K +T Sbjct: 71 QRATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKILQNTGERFKNRTSKKRVTD 130 Query: 4381 KITSTETTEIEHKAQTQERVVEGP 4404 K+ E KA+ E ++ P Sbjct: 131 KVKDKLPQTPEKKAEVLETLINSP 154 >SB_33143| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 234 Score = 36.3 bits (80), Expect = 0.61 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 3/93 (3%) Query: 4328 QTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTET 4387 +TE +TE + + T+ + + S+ E + T+K +K+ + KI + + Sbjct: 53 KTETITETKRSDEETKSDQETNRSDEVTKRSEPETTDR--TEKVEESEKQNSDKINNNDE 110 Query: 4388 TEIEHKAQTQ-ERVVEGPVKPSKPPIFTKKMQP 4419 T+IE A+ E ++GP P+ P T P Sbjct: 111 TQIESNAEAPIEAKLDGPTSPTSPTTPTSPRTP 143 >SB_54309| Best HMM Match : SH2 (HMM E-Value=5.1e-17) Length = 1249 Score = 36.3 bits (80), Expect = 0.61 Identities = 39/186 (20%), Positives = 82/186 (44%), Gaps = 10/186 (5%) Query: 4220 ETTQYQRTETELEKTFEERQVLQR--QGVIDHRPELKPKVIKEPETEWQQ-SVKRKKNEE 4276 E + QR E E ++ +ERQ ++ Q + D R + I E E ++ +R+K + Sbjct: 432 EEDERQRAEDERQRAEDERQRVKHEMQRLKDERRRAEEDEIARQEEELRRLQEQREKELK 491 Query: 4277 YYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQR 4336 Y +LQ E E+ KE+ RE Q D++ + A+R +Q E++ Sbjct: 492 RYKELQMAEEEKRRKETEERE--RQAREEEDRIRRE---REEAERLRREKEQREQLVPHS 546 Query: 4337 VQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQT 4396 + KP + E+ + +++ +++ + + + + +++ E KAQ Sbjct: 547 DALECAIKPL--NLLEARIKAQKLEEEQRELERLQAEAELKRKQELERLREKRKEEKAQR 604 Query: 4397 QERVVE 4402 + ++E Sbjct: 605 ERELIE 610 Score = 32.3 bits (70), Expect = 9.9 Identities = 34/175 (19%), Positives = 78/175 (44%), Gaps = 13/175 (7%) Query: 4228 ETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENE 4287 E + E +E ++++ + + EL + + E E Q+ +R+ EE E + Sbjct: 141 EVDAEAKQKEAELIEDKLAEEKARELAHQEMLRKEQEQQEEEERRIREEE-------ERQ 193 Query: 4288 QVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTE--EVTEQRVQKKVTQKP 4345 + +KE R+R+ + + + K +R E + E E+ ++R +++ Q+ Sbjct: 194 KALKEERMRKLQEEARLAAQRALEEK-RKLEEERKEQERKEKELAELEKKRQEERRRQEE 252 Query: 4346 RIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERV 4400 + E+ +E A++K +E + ++ K E ++E + + +ERV Sbjct: 253 KRRAEEEAKRKAEEEKAAREKAEMEEKLRRLKLQEK---EEKRKLEAEKKEKERV 304 >SB_26345| Best HMM Match : DUF1531 (HMM E-Value=2.4) Length = 169 Score = 36.3 bits (80), Expect = 0.61 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 6/130 (4%) Query: 4270 KRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQT 4329 + K NEE L E E ++ K+ ++ T + +P T A+ ++ ++ + Sbjct: 44 QEKSNEE----LPESEKKKKKKKKDKKKKTEEETVPETVQTETPSARKKKKKEKEQEETM 99 Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI-TSTETT 4388 EE + +K R + E E K+K+ + E D EI I TS + Sbjct: 100 EEQQTEATSSAKKKKKRKVEDVEDVEEKVEAETPKKKKKKSETTED-EIEESINTSEKKK 158 Query: 4389 EIEHKAQTQE 4398 + + K QT+E Sbjct: 159 KKKKKKQTEE 168 >SB_23339| Best HMM Match : I-set (HMM E-Value=1.3e-07) Length = 423 Score = 36.3 bits (80), Expect = 0.61 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 11/83 (13%) Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435 PV PL ++D E +T C+ I GD + + W N+ L+++ S T + Sbjct: 122 PVIFSPLPDVD-AYENKTITLQCQAI--GDAVISIAWLHNDTLVQNRSVNT--------A 170 Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458 + IS + G + C ASN LG Sbjct: 171 LVISKIPLNMSGSWRCVASNHLG 193 Score = 35.1 bits (77), Expect = 1.4 Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 9/73 (12%) Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459 D D E K C+ G + W ND ++ N S N AL+I+ + L+ Sbjct: 130 DVDAYENKTITLQCQAIGDAVISIAWLHNDTLVQ---------NRSVNTALVISKIPLNM 180 Query: 460 SGVVTCVARNKSG 472 SG CVA N G Sbjct: 181 SGSWRCVASNHLG 193 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 8/80 (10%) Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682 P I PL D E + I C+ +G + ++ W D L++ +R+ + L I Sbjct: 122 PVIFSPLPDVDAYENKTITLQCQAIGDAVISIAWLHNDTLVQ-------NRSVNT-ALVI 173 Query: 4683 SEAFPEDEGDYKCVAYNSAG 4702 S+ G ++CVA N G Sbjct: 174 SKIPLNMSGSWRCVASNHLG 193 Score = 33.1 bits (72), Expect = 5.7 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 11/99 (11%) Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236 PV PL + E K I L+C + +GD + + W HN V S T + Sbjct: 122 PVIFSPLPDVDAY-ENKTITLQC--QAIGDAVISIAWLHNDTLVQNRS-VNTALVISKIP 177 Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275 L++ +G + A NHLGS + + V V + SD+ Sbjct: 178 LNM-------SGSWRCVASNHLGSQNKTFFVGVKKPSDL 209 >SB_18255| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1457 Score = 36.3 bits (80), Expect = 0.61 Identities = 41/179 (22%), Positives = 81/179 (45%), Gaps = 21/179 (11%) Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279 ET +Y + + EK E+R R+ ELK K + E + + + +E+ Sbjct: 98 ETERYSAIQ-QAEKALEDRNFAIRES------ELKSKQLMEKYS----LLSKTASEDANA 146 Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339 K +EL+ + + E L + + A +++ + +A + AQR +L++ TE++ + Sbjct: 147 KCRELKEKLSLAEKSLSDRDAELAQLRNEINQSVMAFNNAQRESIDLEKQLAATERKHNE 206 Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE 4398 +++ D + + +E H+A+Q V E +I+S E E E K + E Sbjct: 207 LISEY----DSLNAKLQAREQHIAEQ------AVSIVEYKHRISSLEQNESECKERLFE 255 >SB_15709| Best HMM Match : CAP_GLY (HMM E-Value=0) Length = 729 Score = 36.3 bits (80), Expect = 0.61 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 4/165 (2%) Query: 4232 EKTFEERQ--VLQRQGVIDHRPELKPKVIKEPETEWQQSVKRK-KNEEYYNKLQELENEQ 4288 EK +E Q + Q+Q ++ + E+ V + E + ++ + K +NE K++++E++ Sbjct: 492 EKQIQELQSKIRQQQEQLEQQREITDTVSTDLEEKAKELEEAKSENEAISGKMKDMESQL 551 Query: 4289 VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIP 4348 L + + KVT + S+AQ + N D Q Q ++++ + Sbjct: 552 TSIADELASTKEALKLSQHKVTELESSLSVAQLTQSNNDSNTLQQLQEKQSRISELEQEL 611 Query: 4349 DPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHK 4393 ++ + + + K + V D E +K E TE HK Sbjct: 612 ASNQLSYEELQTDLEFTKAELQSTVEDNEALKKQVE-ELTETIHK 655 >SB_6057| Best HMM Match : ig (HMM E-Value=7.3e-06) Length = 814 Score = 36.3 bits (80), Expect = 0.61 Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 22/154 (14%) Query: 4653 TVQWYKGDKL-IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711 ++ WYK + + P KY M T+ E + + G Y C A N + LK Sbjct: 631 SITWYKDHRSRVVPDKYIDMLTCQRSLTIGSVEVY--EAGRYTCQARNIYASANDSCVLK 688 Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ--------WLREGALIPE 4763 V A N+ + RD+V+ +G K + + + T + W + G L+P Sbjct: 689 VAP---AVNIMWM---RDLVI-DGVQIDHKVVLGTALNITCEVIHARGAWWQKNGLLLPH 741 Query: 4764 TPDFQMIHEGNNAVLLI----GNTYEEDTGTFTC 4793 M NNA L++ + D G +TC Sbjct: 742 NVTHFMRRADNNARLILHIWFNRVQKNDEGNYTC 775 Score = 35.5 bits (78), Expect = 1.1 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002 + W KD R + +LTI SV V++AG YTC+A N A S L + Sbjct: 632 ITWYKDHRSRVVPDKYIDMLTCQR-SLTIGSVEVYEAGRYTCQARNIYASANDSCVLKVA 690 Query: 1003 TKKDII 1008 +I+ Sbjct: 691 PAVNIM 696 Score = 34.7 bits (76), Expect = 1.9 Identities = 41/174 (23%), Positives = 74/174 (42%), Gaps = 22/174 (12%) Query: 4534 DTKVTGTKPIDVYWLKNGK-KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592 D+ T T+ + + W K+ + +V PD +L + T+ +E Y ++G+Y C A N Sbjct: 622 DSTSTQTQ-VSITWYKDHRSRVVPDKYIDMLTCQRSLTIGSVEVY--EAGRYTCQARNIY 678 Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIVAEGQAIEFSCKIVGKPL 4651 A + CV+ K P +I+ ++ D V G A+ +C+++ Sbjct: 679 ASA--NDSCVL-------KVAPAVNIMWMRDLVIDGVQIDHKVVLGTALNITCEVIHA-- 727 Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF-----PEDEGDYKCVAYNS 4700 W++ + L+ P R AD I + DEG+Y C+ Y + Sbjct: 728 -RGAWWQKNGLLLPHNVTHFMRRADNNARLILHIWFNRVQKNDEGNYTCLGYRA 780 Score = 33.1 bits (72), Expect = 5.7 Identities = 16/33 (48%), Positives = 20/33 (60%) Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649 L IG V +AG YTC+A N + A SC L+V Sbjct: 657 LTIGSVEVYEAGRYTCQARNIYASANDSCVLKV 689 >SB_43663| Best HMM Match : F-box (HMM E-Value=4e-07) Length = 717 Score = 35.9 bits (79), Expect = 0.80 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%) Query: 3023 EKIQNL-EDSL-RKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSM 3080 E++ +L EDSL R+E P++D+ E +++ KD+ I E + E S IP D S+ Sbjct: 177 EQVSSLREDSLIREENSSIPEEDSSIKEEVSSIHKDVSTIREDSLIREENSSIPEEDSSI 236 >SB_42146| Best HMM Match : GYF (HMM E-Value=5.7e-15) Length = 924 Score = 35.9 bits (79), Expect = 0.80 Identities = 43/200 (21%), Positives = 93/200 (46%), Gaps = 21/200 (10%) Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSV--KRKKNEE 4276 +E ++ E L++ EE + ++Q + + + +V K+ E + QQ KR++ ++ Sbjct: 617 EEEEMRRQQEQMLQRQREEEERRRQQEEAERQRREQEEVFKQQEQQRQQLELQKRQQEQQ 676 Query: 4277 YYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQ- 4335 +LQ+ + E+ + + +R+ Q A Q+ + + + +E+ +Q Sbjct: 677 RQQELQKRQQEEKQRMAEMRQQQQQ-------------ALLRLQQQQQEVQRRKEIQKQM 723 Query: 4336 RVQKKVTQKPRIPDPS--ESTVHGKEVHVAKQKQTQKEVVG-DKEITRKITSTETTEIEH 4392 +Q+K+ QK ++ + S ST + +A+ +Q Q+E +E R I + E ++ Sbjct: 724 ELQQKLQQKRQVSNGSLWGSTSSPAALSLAEIQQQQEERERLQRERQRLILEQQEREQQN 783 Query: 4393 KAQTQERVVEGPVKPSKPPI 4412 +A PV P PP+ Sbjct: 784 RAAAAGWGEHAPVGP--PPV 801 >SB_36901| Best HMM Match : I-set (HMM E-Value=7.3e-09) Length = 84 Score = 35.9 bits (79), Expect = 0.80 Identities = 15/29 (51%), Positives = 20/29 (68%) Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKIT 3786 D + +AG YTC ATN+ GS TTT ++T Sbjct: 53 DSVTRSEAGTYTCTATNEIGSDTTTVQVT 81 Score = 33.9 bits (74), Expect = 3.2 Identities = 15/29 (51%), Positives = 19/29 (65%) Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 SVT +AG YTC A N IG TT+ +T+ Sbjct: 54 SVTRSEAGTYTCTATNEIGSDTTTVQVTV 82 Score = 33.1 bits (72), Expect = 5.7 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY-EEDSGIYTCKATNSKGSATTS 2860 LK+ + P P+ T + + S S+ + + ++G YTC ATN GS TT+ Sbjct: 21 LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEIGSDTTT 77 >SB_28769| Best HMM Match : ig (HMM E-Value=1e-06) Length = 213 Score = 35.9 bits (79), Expect = 0.80 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 18/131 (13%) Query: 451 MITNVTLSDSGV--VTCVARNKSGETAFQC-RLNVIEKEQVVAPKFVERFSTLNVREGEP 507 M N+ L G+ +TCV N +G + +NV EK ++ +T+N EG Sbjct: 37 MFHNILLDSVGIHLLTCVPINDAGVGENRSVSMNVTEKLPTIS--ITPLRATVN--EGSV 92 Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567 VV A+G + + W+KDGV G S+L + D Y C + Sbjct: 93 VVFTCLAIGFQSFKNFWKKDGV-----------FKGDGSSLTLSSVGTDDRGNYTCNVTS 141 Query: 568 VAGSTATRARL 578 G+T A L Sbjct: 142 TCGTTMKTASL 152 Score = 33.9 bits (74), Expect = 3.2 Identities = 13/34 (38%), Positives = 22/34 (64%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 +L+++S+ DD G YTC T+ G + TAS+ + Sbjct: 121 SLTLSSVGTDDRGNYTCNVTSTCGTTMKTASLDV 154 Score = 32.3 bits (70), Expect = 9.9 Identities = 13/39 (33%), Positives = 22/39 (56%) Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006 +LT+ SV D G+YTC + G +A+L ++ K + Sbjct: 121 SLTLSSVGTDDRGNYTCNVTSTCGTTMKTASLDVIYKPE 159 >SB_25318| Best HMM Match : fn3 (HMM E-Value=2e-15) Length = 911 Score = 35.9 bits (79), Expect = 0.80 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 3/65 (4%) Query: 1825 EDS--SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF 1882 EDS S+Y R ++V V P F+ + + EGQ + C P+PN+ W+ Sbjct: 368 EDSYISKYVR-STIQVVVTDRPEFVAVPSRVYTIPEGQDLNVPCSARGSPNPNITWLWWT 426 Query: 1883 NGKVL 1887 GK + Sbjct: 427 EGKAV 431 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL-N 501 N N L++ N++ D GV C + + + I+ P+FV S + Sbjct: 340 NNGFNTTLVVGNMSREDEGVFGCQVLVREDSYISKYVRSTIQVVVTDRPEFVAVPSRVYT 399 Query: 502 VREGEPVVLNARAVGTPTPRITW 524 + EG+ + + A G+P P ITW Sbjct: 400 IPEGQDLNVPCSARGSPNPNITW 422 Score = 33.9 bits (74), Expect = 3.2 Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487 S+Y ++ I VT +P FV P + + EGQ ++ C + N+ W+ G+ V Sbjct: 373 SKYVRSTI-QVVVTDRPEFVAVPSRVYTIPEGQDLNVPCSARGSPNPNITWLWWTEGKAV 431 Query: 1488 TI 1489 + Sbjct: 432 VV 433 Score = 32.3 bits (70), Expect = 9.9 Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 2/65 (3%) Query: 1160 SKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS 1219 SK+V Q+ + +P FV S + EG+++++ C +P + W+ G++ Sbjct: 373 SKYVRSTIQV--VVTDRPEFVAVPSRVYTIPEGQDLNVPCSARGSPNPNITWLWWTEGKA 430 Query: 1220 VTVGS 1224 V V S Sbjct: 431 VVVAS 435 Score = 32.3 bits (70), Expect = 9.9 Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 4111 PVFVSLPDAV-TVEEGEWARFCCRVTGHPKPRVMWL 4145 P FV++P V T+ EG+ C G P P + WL Sbjct: 388 PEFVAVPSRVYTIPEGQDLNVPCSARGSPNPNITWL 423 >SB_18127| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 963 Score = 35.9 bits (79), Expect = 0.80 Identities = 15/36 (41%), Positives = 22/36 (61%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736 TLS + + D G YTC TN LG A++T + I++ Sbjct: 396 TLSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIDN 431 Score = 34.7 bits (76), Expect = 1.9 Identities = 14/35 (40%), Positives = 19/35 (54%) Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804 L+ YV D GTYTC N LG A+ + L + + Sbjct: 397 LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIDN 431 Score = 34.3 bits (75), Expect = 2.5 Identities = 13/34 (38%), Positives = 18/34 (52%) Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070 L Y + D GTY C TN +G A+ T + +D Sbjct: 397 LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLID 430 Score = 33.9 bits (74), Expect = 3.2 Identities = 14/33 (42%), Positives = 18/33 (54%) Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201 L Y + D GTY C TN+LG A+ T L + Sbjct: 397 LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLI 429 Score = 32.7 bits (71), Expect = 7.5 Identities = 13/28 (46%), Positives = 16/28 (57%) Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTT 3782 L Y+ + D G YTC TN+ GSA T Sbjct: 397 LSFTYVVSGDKGTYTCNVTNRLGSAIAT 424 >SB_58320| Best HMM Match : I-set (HMM E-Value=0.0099) Length = 88 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 510 LNARAVGTPTPRITWQKDG-VPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567 L +A G P P+ITW K G PI + G S L + + A D Y+C A N Sbjct: 18 LQCKARGVPLPQITWDKPGDQPITAG----VSPISGGSQLQVTTTQDAGDYEQYKCRASN 73 Query: 568 VAGS 571 + GS Sbjct: 74 LLGS 77 >SB_47230| Best HMM Match : I-set (HMM E-Value=0.0028) Length = 88 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567 L +A G P P+ITW K G PI + G S L + + A D Y+C A N Sbjct: 18 LQCKAGGVPLPQITWYKPGGQPITAG----VSPISGGSQLQVTTTQDAGDYGQYKCRASN 73 Query: 568 VAGS 571 + GS Sbjct: 74 LLGS 77 >SB_46724| Best HMM Match : I-set (HMM E-Value=6.1e-11) Length = 133 Score = 35.9 bits (79), Expect = 0.80 Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 18/137 (13%) Query: 445 SGNHALMITNVTLSDSGVVTCVARNK-SGETAFQCRLN-VIEKEQVVAPKFVERFSTLNV 502 SGN T +D+G C A N +G T + VI K + P F+ V Sbjct: 8 SGN-VFTKAGATKADTGQYVCTAVNTVTGNTQTRTASTYVIVKYK---PSFISNSPYQTV 63 Query: 503 REG-EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561 E + + L + G P P +TW +DGV + + ++ + S+A Y Sbjct: 64 NETIDFLKLTCESDGYPAPTVTWSRDGVVV---SQTSVYYSNSVT--------RSEAGTY 112 Query: 562 QCTAQNVAGSTATRARL 578 CTA N GS T ++ Sbjct: 113 TCTATNEMGSDTTTVQV 129 Score = 35.5 bits (78), Expect = 1.1 Identities = 14/23 (60%), Positives = 18/23 (78%) Query: 3764 DAGEYTCRATNKWGSATTTAKIT 3786 +AG YTC ATN+ GS TTT ++T Sbjct: 108 EAGTYTCTATNEMGSDTTTVQVT 130 Score = 32.7 bits (71), Expect = 7.5 Identities = 31/133 (23%), Positives = 58/133 (43%), Gaps = 22/133 (16%) Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639 D+G+Y C A+N+ + K KP + +N+P + + D Sbjct: 21 DTGQYVCTAVNTV-TGNTQTRTASTYVIVKYKP---SFISNSPYQTVNETID-------F 69 Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 ++ +C+ G P PTV W + D ++ +S+T+ Y+ ++ + + G Y C A N Sbjct: 70 LKLTCESDGYPAPTVTWSR-DGVV-------VSQTSVYYSNSVTRS---EAGTYTCTATN 118 Query: 4700 SAGRVTVAAKLKV 4712 G T ++ V Sbjct: 119 EMGSDTTTVQVTV 131 Score = 32.7 bits (71), Expect = 7.5 Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 SVT +AG YTC A N +G TT+ +T+ Sbjct: 103 SVTRSEAGTYTCTATNEMGSDTTTVQVTV 131 >SB_41408| Best HMM Match : I-set (HMM E-Value=0.0042) Length = 88 Score = 35.9 bits (79), Expect = 0.80 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567 L +A G P P+ITW K G PI + G S L + + A D Y+C A N Sbjct: 18 LQCKARGVPLPQITWYKPGGQPITAG----VSPISGGSQLQVTTTQDAGDFGQYKCRASN 73 Query: 568 VAGS 571 + GS Sbjct: 74 LLGS 77 >SB_53713| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 903 Score = 35.5 bits (78), Expect = 1.1 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 17/129 (13%) Query: 4640 IEFSCKIVGKPLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLR-------------ISEA 4685 I +C VG P P + W D + + Y + D+ LR I+++ Sbjct: 264 ITLTCTSVGTPTPLITWVLPDGSQVNSTHYITETEVLDDLELRTRLKRPQPGGSLLITDS 323 Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQIT 4745 D G Y C+A N G TV+A + V + D D + A L D V++ +++ Sbjct: 324 REVDTGVYVCIARNVLGNDTVSANVTV-RKDLVD-VDASITLPD-EVFDDDLLDTESERY 380 Query: 4746 SKIKPTIQW 4754 ++K T +W Sbjct: 381 VELKTTFEW 389 Score = 35.1 bits (77), Expect = 1.4 Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 23/136 (16%) Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516 L D G VT VA + + C +NV +Q + + N + E + L +VG Sbjct: 222 LKDCGYVTPVAVTRMWKVTDVC-MNVTNHKQTIYFQ--------NQGQEENITLTCTSVG 272 Query: 517 TPTPRITW-QKDG-----------VPIIPNPEL--RIHTDGGASTLDIPRAKASDAAWYQ 562 TPTP ITW DG ++ + EL R+ +L I ++ D Y Sbjct: 273 TPTPLITWVLPDGSQVNSTHYITETEVLDDLELRTRLKRPQPGGSLLITDSREVDTGVYV 332 Query: 563 CTAQNVAGSTATRARL 578 C A+NV G+ A + Sbjct: 333 CIARNVLGNDTVSANV 348 >SB_53232| Best HMM Match : OAR (HMM E-Value=0.92) Length = 806 Score = 35.5 bits (78), Expect = 1.1 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 9/144 (6%) Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK--SMAQRYE 4323 ++ +KR K+++YY K + + QVI+ + R + G T + K S +R E Sbjct: 37 KKEIKRAKDKDYYEKNRNKKIAQVIERRKARREETK----GKSRTRTEIKKAASKKRRKE 92 Query: 4324 DNLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITR 4380 EE+ +R ++K ++ R G+E K + K K +T Sbjct: 93 QRATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKNLKNTGERFKNRTSKKRVTD 152 Query: 4381 KITSTETTEIEHKAQTQERVVEGP 4404 K+ E KA+ E ++ P Sbjct: 153 KVKDKLPQTPEKKAEVLETLINSP 176 >SB_39065| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 207 Score = 35.5 bits (78), Expect = 1.1 Identities = 28/140 (20%), Positives = 63/140 (45%), Gaps = 2/140 (1%) Query: 4232 EKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIK 4291 E+ E++Q Q+Q + E + + +E E E +Q ++++ +E + QE E EQ + Sbjct: 19 EQEQEQQQQQQQQEEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQE-QEQEQEQEQE 77 Query: 4292 ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPS 4351 + + +E + ++ + Q E +Q +E EQ +++ Q+ Sbjct: 78 QEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQE-QEQEQEQEQEQEQEQEQEQ 136 Query: 4352 ESTVHGKEVHVAKQKQTQKE 4371 E ++ +Q+Q Q++ Sbjct: 137 EQEQEQEQEQEQEQEQEQEQ 156 Score = 33.5 bits (73), Expect = 4.3 Identities = 22/141 (15%), Positives = 65/141 (46%), Gaps = 1/141 (0%) Query: 4259 KEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSM 4318 ++ + + QQ + ++ E+ + QE E EQ ++ + +E + ++ + Sbjct: 23 EQQQQQQQQEEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQ 82 Query: 4319 AQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEI 4378 Q E +Q +E +++ Q++ ++ + + + +E ++++ ++E ++E Sbjct: 83 EQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQ 142 Query: 4379 TRKITSTETTEIEHKAQTQER 4399 ++ + E E + Q Q+R Sbjct: 143 EQEQEQEQEQEQEQQ-QQQQR 162 >SB_31717| Best HMM Match : I-set (HMM E-Value=2.9e-10) Length = 84 Score = 35.5 bits (78), Expect = 1.1 Identities = 14/23 (60%), Positives = 18/23 (78%) Query: 3764 DAGEYTCRATNKWGSATTTAKIT 3786 +AG YTC ATN+ GS TTT ++T Sbjct: 59 EAGTYTCTATNEMGSDTTTVQVT 81 Score = 32.7 bits (71), Expect = 7.5 Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 973 SVTVHDAGHYTCRAYNAIGQATTSANLTI 1001 SVT +AG YTC A N +G TT+ +T+ Sbjct: 54 SVTRSEAGTYTCTATNEMGSDTTTVQVTV 82 >SB_20109| Best HMM Match : I-set (HMM E-Value=2e-05) Length = 122 Score = 35.5 bits (78), Expect = 1.1 Identities = 29/120 (24%), Positives = 49/120 (40%), Gaps = 10/120 (8%) Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVN 1776 MK +R+ E ++ + P+ RV W R+G+ ++ R H AL+++ V Sbjct: 12 MKQVRLPEGESVDILCDVKSC--PRARVMWSRDGLVLQNQTR---RH-----ALSLRRVE 61 Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDV 1836 +G Y C A NELG + V S + H + + +Q + R V Sbjct: 62 LSHTGIYECDAANELGSVRNKVLVIVTSCPEPASQPSHVESRRLMQSYQGQRAGNRASQV 121 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 10/80 (12%) Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836 +S + + EG+++ C+V+ P ++ W + L + TR H S ++++ Sbjct: 9 LSSMKQVRLPEGESVDILCDVKSC--PRARVMWSRDGLVLQNQTR---RHALSLRRVELS 63 Query: 2837 HTYEEDSGIYTCKATNSKGS 2856 HT GIY C A N GS Sbjct: 64 HT-----GIYECDAANELGS 78 >SB_52206| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 786 Score = 35.5 bits (78), Expect = 1.1 Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 10/111 (9%) Query: 3953 YTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFN 4012 +TS++ + DDL + PP ++ I + E + CQ+ P + +V W N Sbjct: 256 FTSDIAI--DDLRSSCTQVPPE-ISYISPSAKVREGQRFVLRCQVIPKNSSS-EVYWTRN 311 Query: 4013 GKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063 G+ L + R + +A P +G Y+C A+++YG D ++ Sbjct: 312 GERLDNLTRTNDSVIYTQIAE------PSMAGTYVCVASSIYGEDRNSTIL 356 Score = 35.1 bits (77), Expect = 1.4 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 7/86 (8%) Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570 VPP + + + V GQ L +V +VYW +NG+++ R + YT Sbjct: 272 VPPEISYISPSAKVREGQRFVLRCQVIPKNSSSEVYWTRNGERLDNLTRTN---DSVIYT 328 Query: 4571 LLILEAYPQDSGKYECVAINSAGEAR 4596 + A P +G Y CVA + GE R Sbjct: 329 QI---AEPSMAGTYVCVASSIYGEDR 351 Score = 34.7 bits (76), Expect = 1.9 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195 + ++ + S Q P ++I +++GQ C V+P + ++ W NG+ + + Sbjct: 260 IAIDDLRSSCTQVPPEISYISPSAKVREGQRFVLRCQVIPKNSSS-EVYWTRNGERLDNL 318 Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233 TR ++ + IA + +G YVC A + YGED Sbjct: 319 TR----TNDSVIYTQIA--EPSMAGTYVCVASSIYGED 350 Score = 34.3 bits (75), Expect = 2.5 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 7/102 (6%) Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627 D+ T P + + +++EGQR ++IP + ++ +V W N + L + T Sbjct: 264 DLRSSCTQVPPEISYISPSAKVREGQRFVLRCQVIPKNSSS-EVYWTRNGERLDN---LT 319 Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669 TN+ + I P +GTY C A + GE S I IV Sbjct: 320 RTND-SVIYTQIAE--PSMAGTYVCVASSIYGEDRNSTILIV 358 Score = 33.1 bits (72), Expect = 5.7 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 13/98 (13%) Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166 Q P ++ ++ ++EG R C+V P N + W NG+++ T+D Sbjct: 271 QVPPEISYISPSAKVREGQRFVLRCQVIPKNSSS-EVYWTRNGERL---DNLTRTND--- 323 Query: 2167 VALDILYTY-AEDS--GTYMCKATNKLGEAVNTCTLKV 2201 ++YT AE S GTY+C A++ GE N+ L V Sbjct: 324 ---SVIYTQIAEPSMAGTYVCVASSIYGEDRNSTILIV 358 >SB_46304| Best HMM Match : Laminin_G_2 (HMM E-Value=0) Length = 645 Score = 35.5 bits (78), Expect = 1.1 Identities = 14/27 (51%), Positives = 19/27 (70%) Query: 2177 EDSGTYMCKATNKLGEAVNTCTLKVAG 2203 ED+G Y+C+ATNK G A T+K+ G Sbjct: 6 EDAGMYICRATNKEGTAEGFATIKIKG 32 Score = 33.5 bits (73), Expect = 4.3 Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651 V DAG+Y C+ATN+ G A +++KG Sbjct: 3 VTHEDAGMYICRATNKEGTAEGFATIKIKG 32 Score = 32.7 bits (71), Expect = 7.5 Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 3/35 (8%) Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867 +++TH ED+G+Y C+ATN +G+A +++ G Sbjct: 1 MNVTH---EDAGMYICRATNKEGTAEGFATIKIKG 32 Score = 32.3 bits (70), Expect = 9.9 Identities = 15/27 (55%), Positives = 17/27 (62%) Query: 4041 EDSGEYLCRATNLYGMDETKAVIKTTG 4067 ED+G Y+CRATN G E A IK G Sbjct: 6 EDAGMYICRATNKEGTAEGFATIKIKG 32 >SB_27034| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 629 Score = 35.5 bits (78), Expect = 1.1 Identities = 49/213 (23%), Positives = 90/213 (42%), Gaps = 14/213 (6%) Query: 4262 ETEWQQSVKRKKNEEYYNKLQELENEQVIKES-RLRESTHQYAIPGDKVTSNTVAKSMAQ 4320 E+E S K+ ++ K+QELE E + K+ ++ T A P + + + Sbjct: 298 ESEGHLSTHEKRQKKLKQKIQELEKENLSKKPWQMSGETGSKARPINSLLEEDL------ 351 Query: 4321 RYEDNLDQTEEVTEQRVQK-KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEIT 4379 ++ +TE+ Q + K RI D + V K V + + +K++ D+E Sbjct: 352 NFDHTAVAAPPITEETTQNLEDIIKQRIKDEAWDDVERKAKPVLQPYEYKKKMPLDQE-K 410 Query: 4380 RKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK-KMQPCRVFEHEQARFEVEFDGEP 4438 K++ ++ E E+ QT E + + + P + K ++F A F +P Sbjct: 411 SKLSLSQIYEQEYLKQTSEPESKKAAEDEENPAHAEIKTMMTKLFTKLDALSNFHFTPKP 470 Query: 4439 L-PLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470 L P IK N P+ N +I ST +++ Sbjct: 471 LKPEIK-IVTNTPVINME--EIAPVSTSDAMLL 500 >SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 933 Score = 35.1 bits (77), Expect = 1.4 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 8/81 (9%) Query: 2660 VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL------VTLSINSLRNDDSG 2713 + LE + R P K+ W K G + +R+KS + L + SI S ++ D+G Sbjct: 854 IRLECFTDGRPAP--KVTWSKVGDSQPDSSRVKSEILYDLDMRQIGLEYSIISAQSYDAG 911 Query: 2714 IYTCKATNLLGEAVSTASIKI 2734 Y CKATN L A I + Sbjct: 912 TYECKATNKLATASHRVQITV 932 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 8/87 (9%) Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTT--MHDFGYVALN 1771 T PM + A N E G P +V W + G S+R+ + ++D + Sbjct: 840 TFPMSSLTAAYNSTIRLEC--FTDGRPAPKVTWSKVGDSQPDSSRVKSEILYDLDMRQIG 897 Query: 1772 MKY----VNPEDSGTYTCRAINELGEA 1794 ++Y D+GTY C+A N+L A Sbjct: 898 LEYSIISAQSYDAGTYECKATNKLATA 924 Score = 34.3 bits (75), Expect = 2.5 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Query: 642 PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY------IS 695 P+ S+TA I E + G P K+ W K G S SSR S + + Sbjct: 842 PMSSLTAAYNSTIRLECFTD--GRPAPKVTWSKVGDSQPDSSRVKSEILYDLDMRQIGLE 899 Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 ++S D+G Y C+A + A + + V Sbjct: 900 YSIISAQSYDAGTYECKATNKLATASHRVQITV 932 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Query: 3723 GDPTMRIDWFHNGRPFATGSRVHT--LNDFGFIALDIDY--IYAR--DAGEYTCRATNKW 3776 G P ++ W G SRV + L D + ++Y I A+ DAG Y C+ATNK Sbjct: 862 GRPAPKVTWSKVGDSQPDSSRVKSEILYDLDMRQIGLEYSIISAQSYDAGTYECKATNKL 921 Query: 3777 GSATTTAKIT 3786 +A+ +IT Sbjct: 922 ATASHRVQIT 931 Score = 32.3 bits (70), Expect = 9.9 Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 10/91 (10%) Query: 3565 SDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQ 3624 S L + NS+ EC + +V W G SRVK+ + + +IG Y Sbjct: 844 SSLTAAYNSTIRLEC--FTDGRPAPKVTWSKVGDSQPDSSRVKSEILYDLDMRQIGLEYS 901 Query: 3625 ------RDAGLYTCKATNRHGEATVSCKLQV 3649 DAG Y CKATN+ AT S ++Q+ Sbjct: 902 IISAQSYDAGTYECKATNK--LATASHRVQI 930 >SB_13773| Best HMM Match : TolA (HMM E-Value=0.042) Length = 1558 Score = 35.1 bits (77), Expect = 1.4 Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 21/229 (9%) Query: 4227 TETELEKTFEERQVLQRQGVIDHRP----ELKPKV--IKEPETEWQQSVKRKKNEEYYNK 4280 TE EL ++ E + ++R E+ K+ IKE + ++ K+K +EE Sbjct: 1142 TEEELIASYAEDAERAAEAAKEYRERTMFEIAEKINSIKEQRRQQTEAQKKKMDEEIRRL 1201 Query: 4281 LQELENEQVIKESRLRE-STHQYAIPGDKVTSNTVAKSM--AQRYEDNLDQTEEVTEQRV 4337 ELE E+ +E RL E T + A K+ A+ + AQR + E++ ++ Sbjct: 1202 EAELEEERSREELRLAERETERVAKKMKKLQEEEAARQLNAAQRGMSE-QEREKLLKEHD 1260 Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQ 4397 + + E T + +++ +K+ KEIT K E +E + + + Sbjct: 1261 ENMAKFSENLKKEQERTKAALRERLEARRKKKKD-AAMKEIT-KAAKEEKEALEQQQREK 1318 Query: 4398 ERVV--EGPVK-----PSKP--PIFTKKMQPCRVFEHEQARFEVEFDGE 4437 V EG + PS+P P TK +P R + A V F E Sbjct: 1319 LTAVQKEGAYRMAATTPSRPRTPPTTKAGEPQRAVQGTMAEPFVPFSLE 1367 >SB_8750| Best HMM Match : Neuromodulin (HMM E-Value=5.7) Length = 247 Score = 35.1 bits (77), Expect = 1.4 Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 3009 LIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISE 3062 L++ QHPK ++ +N ED E +QPD D + PE V+K +IS+ Sbjct: 170 LLDTKQHPKDVSEDKEEKNDEDQPETEESEQPDADEDK-PEMDEVYKPQDEISQ 222 >SB_5736| Best HMM Match : I-set (HMM E-Value=0.0048) Length = 449 Score = 35.1 bits (77), Expect = 1.4 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 10/91 (10%) Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462 V E + C+ TGR + W +N+ I+ N S + AL + TL+ +G Sbjct: 3 VYENETVALKCKATGRAPLYIAWLLNNLVIK---------NNSLDTALALNVTTLNMTGT 53 Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493 V CVA N G + V +K + KF Sbjct: 54 VNCVATNSLGSDSKSFHFRV-KKPYEMCAKF 83 >SB_47260| Best HMM Match : ig (HMM E-Value=4.3e-13) Length = 402 Score = 35.1 bits (77), Expect = 1.4 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 3/62 (4%) Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753 I L ++++ +DSG Y+CR G A + L +TP T+ SQ LQY ++ D Sbjct: 205 ILLRVVNVTYRDSGWYSCRVFDKYGKAFKQGFLAITPAPTL---SQQDLQLQYTRRYADN 261 Query: 754 SK 755 K Sbjct: 262 PK 263 Score = 33.5 bits (73), Expect = 4.3 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 2969 VTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012 + L +V+V RDSG Y+C+ ++K G+AF + T L ++ Sbjct: 205 ILLRVVNVTYRDSGWYSCRVFDKYGKAFKQGFLAITPAPTLSQQ 248 Score = 33.1 bits (72), Expect = 5.7 Identities = 22/103 (21%), Positives = 42/103 (40%), Gaps = 5/103 (4%) Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETA-FQCRLN 481 +TW+ + +++ ++ +N L+++N+ L+D G TCV + +S T L Sbjct: 59 ITWYKYNEPLQE-VTYRDAIN---TRMLILSNLLLADGGRYTCVLKTESNRTLNTSYMLT 114 Query: 482 VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524 + + Q P + V G+ TP I W Sbjct: 115 INDHSQNKKPSIITHSINQTVIIGKTATFTCTITSFSTPYIEW 157 Score = 32.3 bits (70), Expect = 9.9 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 6/104 (5%) Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 ++ WYK ++ ++ Y T L +S D G Y CV + R T+ + Sbjct: 58 SITWYKYNEPLQEVTYRDAINTR---MLILSNLLLADGGRYTCVLKTESNR-TLNTSYML 113 Query: 4713 TQPDQADNL-PAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754 T D + N P++ T + V G+ A F ITS P I+W Sbjct: 114 TINDHSQNKKPSIITHSINQTVIIGKTATFTCTITSFSTPYIEW 157 >SB_6962| Best HMM Match : I-set (HMM E-Value=0.0042) Length = 88 Score = 35.1 bits (77), Expect = 1.4 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 510 LNARAVGTPTPRITWQKDG-VPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567 L +A G P+P+ITW K G PI + G S L + + A D Y+C A N Sbjct: 18 LQCKARGVPSPQITWYKPGDQPITAG----VSPISGGSQLQVTTTQDAGDYGQYKCRASN 73 Query: 568 VAGS 571 GS Sbjct: 74 RLGS 77 >SB_53159| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1540 Score = 34.7 bits (76), Expect = 1.9 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568 L +A G P+ ITW K G PI +L GG+ A D Y+C A N+ Sbjct: 18 LQCKARGVPSAHITWYKPGGQPITAEVKL---ISGGSQLQVTTTQDAGDYGQYKCRASNL 74 Query: 569 AGS 571 GS Sbjct: 75 LGS 77 >SB_44172| Best HMM Match : Pkinase_Tyr (HMM E-Value=6.3e-20) Length = 637 Score = 34.7 bits (76), Expect = 1.9 Identities = 15/34 (44%), Positives = 20/34 (58%) Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734 TLS + + D G YTC TN LG A++T + I Sbjct: 120 TLSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLI 153 Score = 34.7 bits (76), Expect = 1.9 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-KASLQLESQHESALQKIQQ 1823 L+ YV D GTYTC N LG A+ + L + + + + L+ E+ K+++ Sbjct: 121 LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIGNVRITFLLKITSETYSSKLKE 175 Score = 34.7 bits (76), Expect = 1.9 Identities = 15/37 (40%), Positives = 19/37 (51%) Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR 2205 L Y + D GTY C TN+LG A+ T L + R Sbjct: 121 LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIGNVR 157 Score = 33.1 bits (72), Expect = 5.7 Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 1/56 (1%) Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810 L Y+ + D G YTC TN+ GSA T + R I ++ K+KE Sbjct: 121 LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIGNVR-ITFLLKITSETYSSKLKE 175 Score = 32.3 bits (70), Expect = 9.9 Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 1/55 (1%) Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDEQRLKKIQE 2090 L Y + D GTY C TN +G A+ T + + + + L E K++E Sbjct: 121 LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIGNVRITFLLKITSETYSSKLKE 175 >SB_30807| Best HMM Match : I-set (HMM E-Value=7.8e-08) Length = 148 Score = 34.7 bits (76), Expect = 1.9 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 9/104 (8%) Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458 + RDV E K C +GRP P VTW +N + + + +G+ L + + Sbjct: 18 RSRDVAEDKDFSITCSASGRPAPNVTW-VNKT------SGSPVAHGTGSAILSLLKIQRH 70 Query: 459 DSGVVTCVARN--KSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500 +GV C A N K G +NV + V+ + STL Sbjct: 71 QAGVYQCQATNDVKRGAITQDFTINVQCEYNVMCYPDIFSVSTL 114 >SB_22350| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1967 Score = 34.7 bits (76), Expect = 1.9 Identities = 31/154 (20%), Positives = 75/154 (48%), Gaps = 5/154 (3%) Query: 4219 DETTQYQRTETELEKTFEE-RQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEY 4277 D+ ++ R + LE+T + ++V++R+G ++ + +++ E +S ++ E Sbjct: 1806 DQEAKHNRQKNTLEQTVAKMKEVMERKGGDANKVNARVAELEKELKEKTKSAEKLVKEGT 1865 Query: 4278 YNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRV 4337 + E E +Q+ +E T + I K+T+ + +++ YE ++++E + + Sbjct: 1866 LSVYIE-EKDQLQRELDALRKT-EAGIEVSKLTTTSSQVEISRDYE--IEKSEILVKLEQ 1921 Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKE 4371 ++ V K + S + KE + KQ+ +KE Sbjct: 1922 KEGVIAKMKTQQKSSDSAAAKEKRLLKQQLKEKE 1955 >SB_21400| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1531 Score = 34.7 bits (76), Expect = 1.9 Identities = 47/200 (23%), Positives = 90/200 (45%), Gaps = 13/200 (6%) Query: 4230 ELEKTFEERQV-LQRQG-----VIDHRPELKPKV-IKEPETEWQQSVKRKKNEEYYNKLQ 4282 +LE+ ERQ LQ++ + D R L+ +V + E E + +++ + + E + KLQ Sbjct: 770 KLEQALSERQTALQKEQERAREMQDSRLHLQQQVTLIEQEIDRERNASQLETNEMHQKLQ 829 Query: 4283 ELENEQVIKESRLRE-STHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKV 4341 E E K S L+E S+ + D TS+ + Q ++ Q + + Q Sbjct: 830 EARAELEKKTSELKELSSTMREMHQDMKTSSASIVELEQLLQEARTQNDRHSVQLQTTDH 889 Query: 4342 TQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQ---TQE 4398 K S+ T E+ K ++T++E + D++ E T++++ Q TQ Sbjct: 890 AYKETKASLSQQTKRNGELE-EKLRRTEEE-LKDRDGQVAKLDNELTKLQNDFQDTITQL 947 Query: 4399 RVVEGPVKPSKPPIFTKKMQ 4418 + +E + SK + K+ + Sbjct: 948 KTLEDLLDTSKRVVEEKEQK 967 >SB_20351| Best HMM Match : I-set (HMM E-Value=1.9e-13) Length = 142 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 8/80 (10%) Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682 P I KD I E + ++ SC+ G + W +GD +++ +R++D L + Sbjct: 59 PMIYPKPKDVIAYENEDVKLSCQATGDTPFHIAWLRGDVILQ-------NRSSDT-DLVL 110 Query: 4683 SEAFPEDEGDYKCVAYNSAG 4702 S D G Y C NS G Sbjct: 111 SAVKANDSGIYTCCTTNSLG 130 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 8/84 (9%) Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787 +D++ YE + + Q T I WLR ++ + ++ L++ D Sbjct: 66 KDVIAYENEDVKLSCQATGDTPFHIAWLRGDVILQ--------NRSSDTDLVLSAVKAND 117 Query: 4788 TGTFTCRATTAAGQVETSAKLVVK 4811 +G +TC T + G S L+VK Sbjct: 118 SGIYTCCTTNSLGSDSKSLVLLVK 141 Score = 33.9 bits (74), Expect = 3.2 Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 10/93 (10%) Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770 P+ KD+ EN+ + GD + WLR V ++ NR + L Sbjct: 59 PMIYPKPKDVIAYENEDVKLSCQA--TGDTPFHIAWLRGDVILQ--NRSSDTD------L 108 Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803 + V DSG YTC N LG S L V+ Sbjct: 109 VLSAVKANDSGIYTCCTTNSLGSDSKSLVLLVK 141 Score = 33.1 bits (72), Expect = 5.7 Identities = 26/93 (27%), Positives = 35/93 (37%), Gaps = 10/93 (10%) Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617 P P D+I EN C+ D+ + W G +L T L Sbjct: 59 PMIYPKPKDVIAYENEDVKLSCQA--TGDTPFHIAWLR-GDVILQNRSSDTD-------L 108 Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650 + V D+G+YTC TN G + S L VK Sbjct: 109 VLSAVKANDSGIYTCCTTNSLGSDSKSLVLLVK 141 Score = 32.3 bits (70), Expect = 9.9 Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 10/79 (12%) Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383 E +V L C Q GD + W G I + + D V L +V DSG+Y Sbjct: 72 ENEDVKLSC--QATGDTPFHIAWL-RGDVILQNR----SSDTDLV---LSAVKANDSGIY 121 Query: 1384 TCQATNQLGEAVTSCALRV 1402 TC TN LG S L V Sbjct: 122 TCCTTNSLGSDSKSLVLLV 140 >SB_11517| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 240 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 3/72 (4%) Query: 4225 QRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEW--QQSVKRKKNEEYYNKLQ 4282 Q ++E+ E +VLQ Q + + + + +KE E EW +Q+ R + EE+ K + Sbjct: 159 QEAMEQMERNRETLRVLQLQSEANAKQREEERRLKELEAEWLKEQNAMRAQEEEFL-KQE 217 Query: 4283 ELENEQVIKESR 4294 +L ++ K +R Sbjct: 218 KLRKQEAAKRAR 229 >SB_3226| Best HMM Match : RNA_pol_Rpb2_1 (HMM E-Value=0.021) Length = 1217 Score = 34.7 bits (76), Expect = 1.9 Identities = 27/106 (25%), Positives = 54/106 (50%), Gaps = 8/106 (7%) Query: 4198 KVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKV 4257 ++IP D + L+ + Y ++Q + +LE+ +ER ++R+ I R E K Sbjct: 699 RMIPDKDAFINTLRESRTEEYQ--AKFQAFQAKLEQVRKERLEVRRKRRIKDRKERKKIE 756 Query: 4258 IKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYA 4303 ++E + Q+ +RK+ EE + +E E+ +E++ RE + A Sbjct: 757 MEEAKKREQEEKERKEKEE----KERIEREE--REAKEREYAERIA 796 Score = 33.1 bits (72), Expect = 5.7 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Query: 4225 QRTETELEKTFEERQVLQ---RQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKL 4281 Q + +K E+ Q+ Q R +H+ L+ K + E E+ +SV +++ Y K+ Sbjct: 485 QHDHIKAKKREEQEQMAQNYLRTARKEHKLMLERKTVIEARKEYLESVMQERERREYEKI 544 Query: 4282 --QELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMA 4319 Q++EN++ ++ RL E Q I + + K A Sbjct: 545 KKQKVENQEA-EQKRLDEERRQREIQRRRQELQDIEKRQA 583 >SB_26427| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 323 Score = 34.7 bits (76), Expect = 1.9 Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKIT 3786 D + +AG YTC ATN+ GS TT ++T Sbjct: 222 DSVTRSEAGTYTCTATNEMGSDATTVQVT 250 >SB_20144| Best HMM Match : E-MAP-115 (HMM E-Value=0.41) Length = 416 Score = 34.7 bits (76), Expect = 1.9 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 3/72 (4%) Query: 4225 QRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEW--QQSVKRKKNEEYYNKLQ 4282 Q ++E+ E +VLQ Q + + + + +KE E EW +Q+ R + EE+ K + Sbjct: 119 QEAMEQMERNRETLRVLQLQSEANAKQREEERRLKELEAEWLKEQNAMRAQEEEFL-KQE 177 Query: 4283 ELENEQVIKESR 4294 +L ++ K +R Sbjct: 178 KLRKQEAAKRAR 189 >SB_16370| Best HMM Match : I-set (HMM E-Value=0.0024) Length = 82 Score = 34.7 bits (76), Expect = 1.9 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567 L +A G P P+ITW K G PI + G+S L + + A D Y+C A N Sbjct: 11 LQCKARGVPLPQITWYKPGGQPITAG----VSPISGSSQLQVTTTQDAGDYGQYKCRASN 66 Query: 568 VAGS 571 GS Sbjct: 67 RLGS 70 Score = 32.7 bits (71), Expect = 7.5 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 2/65 (3%) Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699 + CK G PLP + WYK + +S ++ +A D G YKC A N Sbjct: 9 LSLQCKARGVPLPQITWYKPGGQPITAGVSPISGSSQLQVTTTQDA--GDYGQYKCRASN 66 Query: 4700 SAGRV 4704 G V Sbjct: 67 RLGSV 71 >SB_15350| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1126 Score = 34.7 bits (76), Expect = 1.9 Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 11/130 (8%) Query: 4253 LKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQV--IKESRLRE--STHQYAIPGDK 4308 ++ K KE E Q ++R+K E K +E + ++V ++ R RE + + DK Sbjct: 761 IEEKAKKERERMEQLEIQRQKKVEEQKKKREEKEKRVAELRAERQRELMEKKKQLLEKDK 820 Query: 4309 VTSNTV--AKSMAQRYED-----NLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVH 4361 + S AK +R ED L + ++ +R Q++ T+K R + E +E+ Sbjct: 821 LISTLTEKAKKKKEREEDAKRRLRLQKKADLDARRKQEEETRKQRQLEQEEEAKRHQELL 880 Query: 4362 VAKQKQTQKE 4371 + KQ+ ++E Sbjct: 881 LRKQEFEEQE 890 >SB_50666| Best HMM Match : ig (HMM E-Value=2.8e-20) Length = 293 Score = 34.3 bits (75), Expect = 2.5 Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 13/103 (12%) Query: 626 PPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF 685 P G + PP P S TA+EG + + G + WL++G+ + + Sbjct: 98 PRGTWGERHAPPMITRPTPSQTAVEGANVTLVC--DATGSSPLNTTWLRDGRIVASGE-- 153 Query: 686 TSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728 +L + S+ + GEY C+A ++ A++ A + V Sbjct: 154 ---------NLLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQV 187 Score = 33.9 bits (74), Expect = 3.2 Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 14/118 (11%) Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749 E+ PP T V EG V C + G + W +GR A+G Sbjct: 104 ERHAPPMITRPTPSQTAV-EGANVTLVC--DATGSSPLNTTWLRDGRIVASGEN------ 154 Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEK 3807 L I I + GEY C+A N +A +TA+I + +V + + + GE+ Sbjct: 155 -----LLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQVDFGKPVVPAALMNRPTRGER 207 Score = 33.9 bits (74), Expect = 3.2 Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 16/154 (10%) Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888 PP S T E V C + L W R+G+++ SG + Sbjct: 108 PPMITRPTPSQTAVEGANVTLVC--DATGSSPLNTTWLRDGRIVASGE-----------N 154 Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISC---KKLPDIILQNQVPRGMKRSEALTQ 3945 L I + ++ GEY+C+A N + A I K + L N+ RG +R Sbjct: 155 LLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQVDFGKPVVPAALMNRPTRGERRFAYWAL 214 Query: 3946 MEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQI 3979 E + Y + L+ +K+ R V++I Sbjct: 215 AECILAYYVGTDEGVSEVLHVAGEKRLHRCVSRI 248 Score = 33.5 bits (73), Expect = 4.3 Identities = 23/102 (22%), Positives = 38/102 (37%), Gaps = 11/102 (10%) Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670 +P+ +APP I P + EG + C G W + +++ Sbjct: 97 EPRGTWGERHAPPMITRPTPSQTAVEGANVTLVCDATGSSPLNTTWLRDGRIV------- 149 Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712 A L I ++EG+Y C A NS A+++V Sbjct: 150 ----ASGENLLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQV 187 Score = 33.5 bits (73), Expect = 4.3 Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 11/91 (12%) Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572 PP T + G V L TG+ P++ WL++G+ V LL Sbjct: 108 PPMITRPTPSQTAVEGANVTLVCDATGSSPLNTTWLRDGRIVA-----------SGENLL 156 Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603 I + G+Y C A NS A+ A+ V Sbjct: 157 IPSIGRDEEGEYVCQAENSCSAAKSTAQIQV 187 Score = 33.1 bits (72), Expect = 5.7 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 13/99 (13%) Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370 P +R + VEG NV L C G + W +G+ + +G L Sbjct: 109 PMITRPTPSQTAVEGANVTLVC--DATGSSPLNTTWLRDGRIVASGEN-----------L 155 Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409 + S+ ++ G Y CQA N A ++ ++V K ++ Sbjct: 156 LIPSIGRDEEGEYVCQAENSCSAAKSTAQIQVDFGKPVV 194 Score = 32.7 bits (71), Expect = 7.5 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 14/100 (14%) Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968 P P Q ++ EG A+ + G S L WL+DGR V + Sbjct: 109 PMITRPTPSQTAV-EG--ANVTLVCDATGSSPLNTTWLRDGRIVASGEN----------- 154 Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008 L I S+ + G Y C+A N+ A ++A + + K ++ Sbjct: 155 LLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQVDFGKPVV 194 Score = 32.3 bits (70), Expect = 9.9 Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 13/99 (13%) Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696 G + AP T VEG +V L + L W ++G + +G L Sbjct: 103 GERHAPPMITRPTPSQTAVEGANVTLVCDATGSSP--LNTTWLRDGRIVASGENLL---- 156 Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735 I S+ D+ G Y C+A N A STA I+++ Sbjct: 157 -------IPSIGRDEEGEYVCQAENSCSAAKSTAQIQVD 188 Database: nematostella Posted date: Oct 22, 2007 1:22 PM Number of letters in database: 16,821,457 Number of sequences in database: 59,808 Lambda K H 0.316 0.133 0.391 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 164,020,062 Number of Sequences: 59808 Number of extensions: 7382525 Number of successful extensions: 40849 Number of sequences better than 10.0: 319 Number of HSP's better than 10.0 without gapping: 174 Number of HSP's successfully gapped in prelim test: 145 Number of HSP's that attempted gapping in prelim test: 19149 Number of HSP's gapped (non-prelim): 17308 length of query: 4814 length of database: 16,821,457 effective HSP length: 98 effective length of query: 4716 effective length of database: 10,960,273 effective search space: 51688647468 effective search space used: 51688647468 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 70 (32.3 bits)
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