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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000622-TA|BGIBMGA000622-PA|IPR003599|Immunoglobulin
subtype, IPR003598|Immunoglobulin subtype 2, IPR000577|Carbohydrate
kinase, FGGY, IPR007110|Immunoglobulin-like, IPR013098|Immunoglobulin
I-set, IPR010939|Protein of unknown function DUF1136
         (4814 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_47306| Best HMM Match : I-set (HMM E-Value=0)                      211   9e-54
SB_29786| Best HMM Match : I-set (HMM E-Value=0)                      202   6e-51
SB_31699| Best HMM Match : No HMM Matches (HMM E-Value=.)             199   4e-50
SB_8818| Best HMM Match : I-set (HMM E-Value=0)                       199   4e-50
SB_8817| Best HMM Match : I-set (HMM E-Value=0)                       182   8e-45
SB_47305| Best HMM Match : I-set (HMM E-Value=0)                      180   3e-44
SB_8819| Best HMM Match : I-set (HMM E-Value=0)                       161   2e-38
SB_26711| Best HMM Match : I-set (HMM E-Value=0)                      153   4e-36
SB_54054| Best HMM Match : No HMM Matches (HMM E-Value=.)             116   5e-25
SB_23359| Best HMM Match : I-set (HMM E-Value=0)                      100   3e-20
SB_10606| Best HMM Match : I-set (HMM E-Value=0)                      100   3e-20
SB_59380| Best HMM Match : No HMM Matches (HMM E-Value=.)              99   8e-20
SB_57926| Best HMM Match : I-set (HMM E-Value=3.5e-39)                 97   3e-19
SB_24472| Best HMM Match : I-set (HMM E-Value=0)                       97   4e-19
SB_33342| Best HMM Match : No HMM Matches (HMM E-Value=.)              96   5e-19
SB_37927| Best HMM Match : No HMM Matches (HMM E-Value=.)              96   7e-19
SB_19226| Best HMM Match : I-set (HMM E-Value=0)                       93   7e-18
SB_40832| Best HMM Match : No HMM Matches (HMM E-Value=.)              88   1e-16
SB_45852| Best HMM Match : I-set (HMM E-Value=0)                       87   3e-16
SB_29237| Best HMM Match : I-set (HMM E-Value=0)                       86   6e-16
SB_1528| Best HMM Match : No HMM Matches (HMM E-Value=.)               86   8e-16
SB_8553| Best HMM Match : No HMM Matches (HMM E-Value=.)               85   1e-15
SB_5639| Best HMM Match : No HMM Matches (HMM E-Value=.)               84   3e-15
SB_10900| Best HMM Match : I-set (HMM E-Value=0)                       80   4e-14
SB_43700| Best HMM Match : SRCR (HMM E-Value=0)                        79   9e-14
SB_41825| Best HMM Match : No HMM Matches (HMM E-Value=.)              78   2e-13
SB_40708| Best HMM Match : SRCR (HMM E-Value=0)                        77   4e-13
SB_50799| Best HMM Match : I-set (HMM E-Value=0)                       77   5e-13
SB_40971| Best HMM Match : No HMM Matches (HMM E-Value=.)              76   8e-13
SB_8388| Best HMM Match : ig (HMM E-Value=8.80001e-41)                 75   2e-12
SB_51089| Best HMM Match : I-set (HMM E-Value=1.4e-38)                 75   2e-12
SB_31697| Best HMM Match : No HMM Matches (HMM E-Value=.)              74   2e-12
SB_26454| Best HMM Match : I-set (HMM E-Value=7e-12)                   73   8e-12
SB_12405| Best HMM Match : I-set (HMM E-Value=8.8e-21)                 72   1e-11
SB_11883| Best HMM Match : I-set (HMM E-Value=0)                       70   5e-11
SB_52575| Best HMM Match : No HMM Matches (HMM E-Value=.)              69   7e-11
SB_41626| Best HMM Match : No HMM Matches (HMM E-Value=.)              69   7e-11
SB_53570| Best HMM Match : Y_phosphatase (HMM E-Value=0)               69   9e-11
SB_41623| Best HMM Match : No HMM Matches (HMM E-Value=.)              69   9e-11
SB_14313| Best HMM Match : I-set (HMM E-Value=1.8e-21)                 68   2e-10
SB_30290| Best HMM Match : I-set (HMM E-Value=1.4e-21)                 67   4e-10
SB_24384| Best HMM Match : I-set (HMM E-Value=4.3e-31)                 66   5e-10
SB_14894| Best HMM Match : No HMM Matches (HMM E-Value=.)              66   9e-10
SB_31893| Best HMM Match : I-set (HMM E-Value=2e-22)                   66   9e-10
SB_34975| Best HMM Match : F5_F8_type_C (HMM E-Value=0)                65   1e-09
SB_17403| Best HMM Match : I-set (HMM E-Value=0)                       64   2e-09
SB_57324| Best HMM Match : ig (HMM E-Value=1e-26)                      63   6e-09
SB_2157| Best HMM Match : ig (HMM E-Value=9e-19)                       63   6e-09
SB_20844| Best HMM Match : Ion_trans (HMM E-Value=0)                   63   6e-09
SB_27122| Best HMM Match : I-set (HMM E-Value=1.9e-39)                 62   1e-08
SB_33752| Best HMM Match : I-set (HMM E-Value=3.7e-15)                 61   2e-08
SB_9092| Best HMM Match : No HMM Matches (HMM E-Value=.)               61   2e-08
SB_3191| Best HMM Match : ig (HMM E-Value=3.5e-16)                     60   4e-08
SB_41624| Best HMM Match : No HMM Matches (HMM E-Value=.)              60   4e-08
SB_13651| Best HMM Match : I-set (HMM E-Value=4e-17)                   60   6e-08
SB_59628| Best HMM Match : I-set (HMM E-Value=5e-21)                   60   6e-08
SB_36553| Best HMM Match : No HMM Matches (HMM E-Value=.)              59   1e-07
SB_37863| Best HMM Match : I-set (HMM E-Value=3.1e-14)                 58   2e-07
SB_51604| Best HMM Match : I-set (HMM E-Value=2.3e-21)                 58   2e-07
SB_39029| Best HMM Match : ig (HMM E-Value=6e-10)                      58   2e-07
SB_58150| Best HMM Match : ig (HMM E-Value=3.7e-24)                    57   4e-07
SB_32327| Best HMM Match : ig (HMM E-Value=7.9e-23)                    57   4e-07
SB_14261| Best HMM Match : ig (HMM E-Value=0)                          57   4e-07
SB_15392| Best HMM Match : No HMM Matches (HMM E-Value=.)              56   5e-07
SB_38293| Best HMM Match : No HMM Matches (HMM E-Value=.)              56   9e-07
SB_29770| Best HMM Match : ig (HMM E-Value=3.4e-05)                    55   2e-06
SB_54662| Best HMM Match : No HMM Matches (HMM E-Value=.)              55   2e-06
SB_29852| Best HMM Match : No HMM Matches (HMM E-Value=.)              54   2e-06
SB_16673| Best HMM Match : No HMM Matches (HMM E-Value=.)              54   2e-06
SB_55336| Best HMM Match : No HMM Matches (HMM E-Value=.)              54   2e-06
SB_55607| Best HMM Match : ig (HMM E-Value=4.6e-17)                    54   3e-06
SB_37708| Best HMM Match : No HMM Matches (HMM E-Value=.)              54   3e-06
SB_16652| Best HMM Match : I-set (HMM E-Value=1.2e-37)                 54   3e-06
SB_5575| Best HMM Match : No HMM Matches (HMM E-Value=.)               54   3e-06
SB_30961| Best HMM Match : I-set (HMM E-Value=0)                       54   4e-06
SB_10041| Best HMM Match : ig (HMM E-Value=3.5e-06)                    54   4e-06
SB_46550| Best HMM Match : Asn_synthase (HMM E-Value=0)                52   9e-06
SB_9202| Best HMM Match : ig (HMM E-Value=5e-40)                       52   9e-06
SB_45516| Best HMM Match : I-set (HMM E-Value=1.1e-26)                 52   1e-05
SB_43869| Best HMM Match : ig (HMM E-Value=2.7e-06)                    52   1e-05
SB_9034| Best HMM Match : No HMM Matches (HMM E-Value=.)               52   1e-05
SB_3465| Best HMM Match : No HMM Matches (HMM E-Value=.)               51   2e-05
SB_22798| Best HMM Match : Cadherin (HMM E-Value=0)                    51   2e-05
SB_56900| Best HMM Match : I-set (HMM E-Value=8e-10)                   51   3e-05
SB_54071| Best HMM Match : No HMM Matches (HMM E-Value=.)              51   3e-05
SB_33923| Best HMM Match : No HMM Matches (HMM E-Value=.)              50   3e-05
SB_2143| Best HMM Match : ig (HMM E-Value=1.9e-09)                     50   3e-05
SB_30548| Best HMM Match : I-set (HMM E-Value=2.1e-11)                 50   3e-05
SB_45888| Best HMM Match : Pkinase_Tyr (HMM E-Value=1.4e-25)           50   5e-05
SB_6364| Best HMM Match : No HMM Matches (HMM E-Value=.)               50   5e-05
SB_39808| Best HMM Match : EGF_CA (HMM E-Value=6.3e-35)                50   6e-05
SB_28651| Best HMM Match : ig (HMM E-Value=1.4e-09)                    50   6e-05
SB_56353| Best HMM Match : I-set (HMM E-Value=6.3e-15)                 49   8e-05
SB_24015| Best HMM Match : I-set (HMM E-Value=2.7e-21)                 49   8e-05
SB_52866| Best HMM Match : No HMM Matches (HMM E-Value=.)              49   8e-05
SB_8401| Best HMM Match : ig (HMM E-Value=8.1e-22)                     49   1e-04
SB_21597| Best HMM Match : ig (HMM E-Value=2.9e-14)                    49   1e-04
SB_52846| Best HMM Match : ig (HMM E-Value=9e-12)                      48   1e-04
SB_12096| Best HMM Match : ig (HMM E-Value=9.4e-33)                    48   1e-04
SB_26137| Best HMM Match : Plasmodium_HRP (HMM E-Value=0.27)           48   2e-04
SB_2034| Best HMM Match : No HMM Matches (HMM E-Value=.)               48   2e-04
SB_43033| Best HMM Match : I-set (HMM E-Value=3.3e-18)                 48   2e-04
SB_15415| Best HMM Match : No HMM Matches (HMM E-Value=.)              48   2e-04
SB_42486| Best HMM Match : Pkinase_Tyr (HMM E-Value=0)                 48   2e-04
SB_12208| Best HMM Match : ig (HMM E-Value=6.9e-30)                    48   2e-04
SB_5499| Best HMM Match : No HMM Matches (HMM E-Value=.)               47   3e-04
SB_26664| Best HMM Match : I-set (HMM E-Value=7.6e-06)                 47   4e-04
SB_24434| Best HMM Match : No HMM Matches (HMM E-Value=.)              47   4e-04
SB_59087| Best HMM Match : ig (HMM E-Value=1.5e-27)                    46   6e-04
SB_50854| Best HMM Match : ig (HMM E-Value=6.1e-27)                    46   6e-04
SB_33962| Best HMM Match : No HMM Matches (HMM E-Value=.)              46   6e-04
SB_27603| Best HMM Match : ig (HMM E-Value=2.9e-10)                    46   6e-04
SB_53873| Best HMM Match : Fibrinogen_C (HMM E-Value=0)                46   8e-04
SB_50833| Best HMM Match : Thyroglobulin_1 (HMM E-Value=1.1e-08)       46   8e-04
SB_48846| Best HMM Match : Pkinase_Tyr (HMM E-Value=8.1e-16)           46   8e-04
SB_994| Best HMM Match : I-set (HMM E-Value=6e-15)                     46   0.001
SB_56444| Best HMM Match : fn3 (HMM E-Value=1.2e-21)                   46   0.001
SB_29125| Best HMM Match : I-set (HMM E-Value=1.8e-09)                 46   0.001
SB_53160| Best HMM Match : No HMM Matches (HMM E-Value=.)              45   0.001
SB_51910| Best HMM Match : ig (HMM E-Value=4.9e-05)                    45   0.001
SB_39770| Best HMM Match : TolA (HMM E-Value=0.33)                     45   0.001
SB_13504| Best HMM Match : No HMM Matches (HMM E-Value=.)              45   0.001
SB_31858| Best HMM Match : I-set (HMM E-Value=3.7e-08)                 45   0.001
SB_19207| Best HMM Match : ig (HMM E-Value=1.2e-11)                    45   0.001
SB_18521| Best HMM Match : ig (HMM E-Value=7.5e-11)                    45   0.001
SB_44830| Best HMM Match : I-set (HMM E-Value=1.1e-08)                 45   0.002
SB_37776| Best HMM Match : fn3 (HMM E-Value=1.4e-22)                   44   0.002
SB_25692| Best HMM Match : I-set (HMM E-Value=2e-20)                   44   0.002
SB_19559| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   0.002
SB_16914| Best HMM Match : I-set (HMM E-Value=2.3e-10)                 44   0.002
SB_13005| Best HMM Match : PSI (HMM E-Value=2.9e-11)                   44   0.002
SB_43138| Best HMM Match : Pox_A_type_inc (HMM E-Value=1.3e-14)        43   0.005
SB_33085| Best HMM Match : Trypsin (HMM E-Value=0)                     43   0.005
SB_35648| Best HMM Match : I-set (HMM E-Value=8.5e-05)                 43   0.005
SB_23794| Best HMM Match : ig (HMM E-Value=3.1e-07)                    43   0.007
SB_2033| Best HMM Match : No HMM Matches (HMM E-Value=.)               43   0.007
SB_43971| Best HMM Match : I-set (HMM E-Value=1.7e-09)                 43   0.007
SB_29801| Best HMM Match : Collagen (HMM E-Value=3.2e-12)              42   0.009
SB_3251| Best HMM Match : I-set (HMM E-Value=1.8e-07)                  42   0.009
SB_56336| Best HMM Match : Ag332 (HMM E-Value=5.1)                     42   0.012
SB_49916| Best HMM Match : ig (HMM E-Value=8.5e-06)                    42   0.012
SB_25723| Best HMM Match : Vicilin_N (HMM E-Value=0.0045)              42   0.012
SB_43939| Best HMM Match : I-set (HMM E-Value=1.3e-14)                 42   0.016
SB_1939| Best HMM Match : No HMM Matches (HMM E-Value=.)               42   0.016
SB_49663| Best HMM Match : TolA (HMM E-Value=0.059)                    42   0.016
SB_41418| Best HMM Match : EGF_CA (HMM E-Value=0)                      41   0.021
SB_24813| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.021
SB_1718| Best HMM Match : I-set (HMM E-Value=3.8e-07)                  41   0.021
SB_44749| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.021
SB_26428| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.021
SB_10779| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.021
SB_50998| Best HMM Match : No HMM Matches (HMM E-Value=.)              41   0.028
SB_42485| Best HMM Match : Pkinase_Tyr (HMM E-Value=0)                 41   0.028
SB_10883| Best HMM Match : ig (HMM E-Value=7.00649e-43)                41   0.028
SB_43084| Best HMM Match : ig (HMM E-Value=9.7e-23)                    41   0.028
SB_37145| Best HMM Match : ig (HMM E-Value=8e-07)                      40   0.037
SB_28081| Best HMM Match : ig (HMM E-Value=2e-08)                      40   0.037
SB_21023| Best HMM Match : I-set (HMM E-Value=2e-07)                   40   0.037
SB_42222| Best HMM Match : ig (HMM E-Value=2.1e-17)                    40   0.037
SB_37828| Best HMM Match : No HMM Matches (HMM E-Value=.)              40   0.037
SB_26678| Best HMM Match : I-set (HMM E-Value=1e-07)                   40   0.037
SB_10221| Best HMM Match : No HMM Matches (HMM E-Value=.)              40   0.037
SB_10219| Best HMM Match : No HMM Matches (HMM E-Value=.)              40   0.037
SB_29692| Best HMM Match : ig (HMM E-Value=5.4e-12)                    40   0.049
SB_21223| Best HMM Match : I-set (HMM E-Value=2.8e-11)                 40   0.049
SB_33134| Best HMM Match : No HMM Matches (HMM E-Value=.)              40   0.049
SB_20290| Best HMM Match : ig (HMM E-Value=2.9e-15)                    40   0.049
SB_24046| Best HMM Match : No HMM Matches (HMM E-Value=.)              40   0.065
SB_33855| Best HMM Match : No HMM Matches (HMM E-Value=.)              39   0.086
SB_18843| Best HMM Match : I-set (HMM E-Value=1e-07)                   39   0.086
SB_11246| Best HMM Match : ig (HMM E-Value=7.5e-07)                    39   0.11 
SB_1675| Best HMM Match : ig (HMM E-Value=5.6e-05)                     39   0.11 
SB_43870| Best HMM Match : Pkinase_Tyr (HMM E-Value=0)                 39   0.11 
SB_35812| Best HMM Match : Atrophin-1 (HMM E-Value=0.23)               39   0.11 
SB_23775| Best HMM Match : Tropomyosin (HMM E-Value=0)                 39   0.11 
SB_23345| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.15 
SB_50677| Best HMM Match : I-set (HMM E-Value=6.7e-11)                 38   0.15 
SB_40656| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.20 
SB_26233| Best HMM Match : No HMM Matches (HMM E-Value=.)              38   0.20 
SB_16822| Best HMM Match : I-set (HMM E-Value=1.3e-07)                 38   0.20 
SB_1246| Best HMM Match : Mito_carr (HMM E-Value=1.4013e-45)           38   0.20 
SB_38167| Best HMM Match : Collagen (HMM E-Value=7e-12)                38   0.20 
SB_47033| Best HMM Match : WAP (HMM E-Value=1.8e-38)                   38   0.26 
SB_57573| Best HMM Match : 7tm_2 (HMM E-Value=3.7e-40)                 38   0.26 
SB_50620| Best HMM Match : Lectin_C (HMM E-Value=2.1e-14)              38   0.26 
SB_44087| Best HMM Match : I-set (HMM E-Value=1.5e-05)                 38   0.26 
SB_12530| Best HMM Match : I-set (HMM E-Value=3e-05)                   38   0.26 
SB_11355| Best HMM Match : I-set (HMM E-Value=1.5e-05)                 38   0.26 
SB_7591| Best HMM Match : No HMM Matches (HMM E-Value=.)               38   0.26 
SB_48288| Best HMM Match : ig (HMM E-Value=6.9e-08)                    37   0.35 
SB_50351| Best HMM Match : I-set (HMM E-Value=0.00016)                 37   0.35 
SB_24929| Best HMM Match : ig (HMM E-Value=8.2e-06)                    37   0.35 
SB_21954| Best HMM Match : V-set (HMM E-Value=0.011)                   37   0.35 
SB_11731| Best HMM Match : ig (HMM E-Value=1e-06)                      37   0.35 
SB_43527| Best HMM Match : Trypsin (HMM E-Value=0)                     37   0.46 
SB_30644| Best HMM Match : No HMM Matches (HMM E-Value=.)              37   0.46 
SB_29861| Best HMM Match : RRM_1 (HMM E-Value=1.10002e-42)             37   0.46 
SB_17408| Best HMM Match : I-set (HMM E-Value=7.4e-06)                 37   0.46 
SB_53466| Best HMM Match : SCP (HMM E-Value=2.4e-27)                   37   0.46 
SB_48507| Best HMM Match : TolA (HMM E-Value=1)                        37   0.46 
SB_11578| Best HMM Match : ig (HMM E-Value=3.3e-23)                    37   0.46 
SB_3034| Best HMM Match : I-set (HMM E-Value=5e-09)                    37   0.46 
SB_56618| Best HMM Match : DUF1213 (HMM E-Value=0.022)                 36   0.61 
SB_55200| Best HMM Match : E-MAP-115 (HMM E-Value=0.85)                36   0.61 
SB_49614| Best HMM Match : E-MAP-115 (HMM E-Value=0.85)                36   0.61 
SB_40579| Best HMM Match : E-MAP-115 (HMM E-Value=0.85)                36   0.61 
SB_33143| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   0.61 
SB_54309| Best HMM Match : SH2 (HMM E-Value=5.1e-17)                   36   0.61 
SB_26345| Best HMM Match : DUF1531 (HMM E-Value=2.4)                   36   0.61 
SB_23339| Best HMM Match : I-set (HMM E-Value=1.3e-07)                 36   0.61 
SB_18255| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   0.61 
SB_15709| Best HMM Match : CAP_GLY (HMM E-Value=0)                     36   0.61 
SB_6057| Best HMM Match : ig (HMM E-Value=7.3e-06)                     36   0.61 
SB_43663| Best HMM Match : F-box (HMM E-Value=4e-07)                   36   0.80 
SB_42146| Best HMM Match : GYF (HMM E-Value=5.7e-15)                   36   0.80 
SB_36901| Best HMM Match : I-set (HMM E-Value=7.3e-09)                 36   0.80 
SB_28769| Best HMM Match : ig (HMM E-Value=1e-06)                      36   0.80 
SB_25318| Best HMM Match : fn3 (HMM E-Value=2e-15)                     36   0.80 
SB_18127| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   0.80 
SB_58320| Best HMM Match : I-set (HMM E-Value=0.0099)                  36   0.80 
SB_47230| Best HMM Match : I-set (HMM E-Value=0.0028)                  36   0.80 
SB_46724| Best HMM Match : I-set (HMM E-Value=6.1e-11)                 36   0.80 
SB_41408| Best HMM Match : I-set (HMM E-Value=0.0042)                  36   0.80 
SB_53713| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   1.1  
SB_53232| Best HMM Match : OAR (HMM E-Value=0.92)                      36   1.1  
SB_39065| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   1.1  
SB_31717| Best HMM Match : I-set (HMM E-Value=2.9e-10)                 36   1.1  
SB_20109| Best HMM Match : I-set (HMM E-Value=2e-05)                   36   1.1  
SB_52206| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   1.1  
SB_46304| Best HMM Match : Laminin_G_2 (HMM E-Value=0)                 36   1.1  
SB_27034| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   1.1  
SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.4  
SB_13773| Best HMM Match : TolA (HMM E-Value=0.042)                    35   1.4  
SB_8750| Best HMM Match : Neuromodulin (HMM E-Value=5.7)               35   1.4  
SB_5736| Best HMM Match : I-set (HMM E-Value=0.0048)                   35   1.4  
SB_47260| Best HMM Match : ig (HMM E-Value=4.3e-13)                    35   1.4  
SB_6962| Best HMM Match : I-set (HMM E-Value=0.0042)                   35   1.4  
SB_53159| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.9  
SB_44172| Best HMM Match : Pkinase_Tyr (HMM E-Value=6.3e-20)           35   1.9  
SB_30807| Best HMM Match : I-set (HMM E-Value=7.8e-08)                 35   1.9  
SB_22350| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.9  
SB_21400| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.9  
SB_20351| Best HMM Match : I-set (HMM E-Value=1.9e-13)                 35   1.9  
SB_11517| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.9  
SB_3226| Best HMM Match : RNA_pol_Rpb2_1 (HMM E-Value=0.021)           35   1.9  
SB_26427| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.9  
SB_20144| Best HMM Match : E-MAP-115 (HMM E-Value=0.41)                35   1.9  
SB_16370| Best HMM Match : I-set (HMM E-Value=0.0024)                  35   1.9  
SB_15350| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   1.9  
SB_50666| Best HMM Match : ig (HMM E-Value=2.8e-20)                    34   2.5  
SB_39538| Best HMM Match : VWA (HMM E-Value=0)                         34   2.5  
SB_35470| Best HMM Match : PAN (HMM E-Value=2.9e-08)                   34   2.5  
SB_19232| Best HMM Match : UCR_TM (HMM E-Value=5.1)                    34   2.5  
SB_7833| Best HMM Match : I-set (HMM E-Value=0.0042)                   34   2.5  
SB_53860| Best HMM Match : fn3 (HMM E-Value=3.6e-07)                   34   3.2  
SB_33494| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   3.2  
SB_31639| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   3.2  
SB_18619| Best HMM Match : I-set (HMM E-Value=7.8e-08)                 34   3.2  
SB_5458| Best HMM Match : E-MAP-115 (HMM E-Value=0.3)                  34   3.2  
SB_427| Best HMM Match : I-set (HMM E-Value=1.8e-12)                   34   3.2  
SB_30426| Best HMM Match : CXC (HMM E-Value=2.8)                       34   3.2  
SB_26474| Best HMM Match : No HMM Matches (HMM E-Value=.)              34   3.2  
SB_8304| Best HMM Match : PLAT (HMM E-Value=0)                         34   3.2  
SB_6305| Best HMM Match : Adeno_E3_CR2 (HMM E-Value=0.096)             34   3.2  
SB_50253| Best HMM Match : HYR (HMM E-Value=2.6e-20)                   33   4.3  
SB_47007| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   4.3  
SB_42609| Best HMM Match : I-set (HMM E-Value=1.3)                     33   4.3  
SB_42014| Best HMM Match : Myosin_tail_1 (HMM E-Value=0.083)           33   4.3  
SB_33884| Best HMM Match : I-set (HMM E-Value=7e-08)                   33   4.3  
SB_29610| Best HMM Match : Extensin_2 (HMM E-Value=2.3)                33   4.3  
SB_12442| Best HMM Match : zf-MYND (HMM E-Value=0.0028)                33   4.3  
SB_2459| Best HMM Match : No HMM Matches (HMM E-Value=.)               33   4.3  
SB_46756| Best HMM Match : zf-C2H2 (HMM E-Value=4.60046e-42)           33   4.3  
SB_44178| Best HMM Match : I-set (HMM E-Value=0.52)                    33   4.3  
SB_42560| Best HMM Match : ig (HMM E-Value=2.4e-06)                    33   4.3  
SB_36607| Best HMM Match : Vicilin_N (HMM E-Value=3.7)                 33   4.3  
SB_33276| Best HMM Match : Glyco_transf_43 (HMM E-Value=0)             33   4.3  
SB_28606| Best HMM Match : PAN (HMM E-Value=4.6e-10)                   33   4.3  
SB_28335| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   4.3  
SB_25763| Best HMM Match : MgtE_N (HMM E-Value=1.9)                    33   4.3  
SB_19973| Best HMM Match : I-set (HMM E-Value=2.8e-08)                 33   4.3  
SB_1300| Best HMM Match : No HMM Matches (HMM E-Value=.)               33   4.3  
SB_54138| Best HMM Match : rve (HMM E-Value=6.8e-24)                   33   5.7  
SB_51947| Best HMM Match : 7tm_1 (HMM E-Value=1.4013e-45)              33   5.7  
SB_45950| Best HMM Match : fn3 (HMM E-Value=3e-13)                     33   5.7  
SB_30292| Best HMM Match : fn3 (HMM E-Value=1.2e-12)                   33   5.7  
SB_28604| Best HMM Match : FerB (HMM E-Value=5.19994e-41)              33   5.7  
SB_28014| Best HMM Match : HOOK (HMM E-Value=1.8e-13)                  33   5.7  
SB_21874| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   5.7  
SB_18760| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   5.7  
SB_11738| Best HMM Match : SH3_2 (HMM E-Value=3.7e-32)                 33   5.7  
SB_3082| Best HMM Match : ig (HMM E-Value=1.5e-17)                     33   5.7  
SB_56497| Best HMM Match : Extensin_2 (HMM E-Value=0.16)               33   5.7  
SB_34910| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   5.7  
SB_3422| Best HMM Match : No HMM Matches (HMM E-Value=.)               33   5.7  
SB_50210| Best HMM Match : I-set (HMM E-Value=0.11)                    33   7.5  
SB_28589| Best HMM Match : ig (HMM E-Value=1.1e-05)                    33   7.5  
SB_17203| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   7.5  
SB_14859| Best HMM Match : SEA (HMM E-Value=0.01)                      33   7.5  
SB_10643| Best HMM Match : ShTK (HMM E-Value=2.9e-23)                  33   7.5  
SB_48968| Best HMM Match : Dehydrin (HMM E-Value=0.99)                 33   7.5  
SB_31398| Best HMM Match : No HMM Matches (HMM E-Value=.)              33   7.5  
SB_21196| Best HMM Match : I-set (HMM E-Value=1.3)                     33   7.5  
SB_7500| Best HMM Match : No HMM Matches (HMM E-Value=.)               33   7.5  
SB_1762| Best HMM Match : I-set (HMM E-Value=2.8e-12)                  33   7.5  
SB_55799| Best HMM Match : Na_trans_assoc (HMM E-Value=1.5)            32   9.9  
SB_52732| Best HMM Match : M (HMM E-Value=0.019)                       32   9.9  
SB_29011| Best HMM Match : ig (HMM E-Value=2.7e-06)                    32   9.9  
SB_20689| Best HMM Match : Gelsolin (HMM E-Value=0.00029)              32   9.9  
SB_812| Best HMM Match : FH2 (HMM E-Value=0)                           32   9.9  
SB_57625| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   9.9  
SB_56996| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   9.9  
SB_51340| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   9.9  
SB_42488| Best HMM Match : ig (HMM E-Value=4.2e-06)                    32   9.9  
SB_36059| Best HMM Match : TolA (HMM E-Value=0.1)                      32   9.9  
SB_28927| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   9.9  
SB_9820| Best HMM Match : No HMM Matches (HMM E-Value=.)               32   9.9  
SB_6600| Best HMM Match : No HMM Matches (HMM E-Value=.)               32   9.9  
SB_3562| Best HMM Match : Ribosomal_60s (HMM E-Value=2.1)              32   9.9  

>SB_47306| Best HMM Match : I-set (HMM E-Value=0)
          Length = 1260

 Score =  211 bits (516), Expect = 9e-54
 Identities = 209/885 (23%), Positives = 360/885 (40%), Gaps = 100/885 (11%)

Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028
            K   P  +++++ Q  +VE E     C ++  G P   VEW   GKPL   +   P Y+ 
Sbjct: 424  KGTAPTILSEMKPQ-QVVEGEDVMLACAVS--GKPEPTVEWLKEGKPLSRDSHVRPKYEA 480

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIR 4088
                + F     ED   Y C ATN  G   + A ++   KP I      P+    +    
Sbjct: 481  EIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEI----SAPESTTPV---- 532

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
              E +    P+  +E++ A   PV   L D  +V  G+ A+   RVTG PKP V W  +G
Sbjct: 533  -AETALMSKPKD-LEKTGA---PVIKELKD-TSVPIGQEAKLDARVTGSPKPEVEWFKDG 586

Query: 4149 NTIVNGSRYKLTYD---GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDD 4205
              + +  R+    D    ++   I   +  D GK + I             L +     +
Sbjct: 587  KVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSI----KE 642

Query: 4206 YRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEW 4265
                      P  D   + + T  +     +ER  ++ +   D R + + +   EPE EW
Sbjct: 643  ETETAPEKVEPTADVGVKEELTAPKFMD--KERGPIEVEEGEDVRLKTRVRGQPEPEIEW 700

Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPG-----------DKVTSNTV 4314
             ++ +  +  E  N     E   +  E+   E T  Y               + +     
Sbjct: 701  LRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKA 760

Query: 4315 AKSMAQRYEDNLDQTEEVTEQRVQKKVT----QKPRIPDPSESTVHGKEVHVAKQK---- 4366
               +A +  + +   E   +Q V+  +T    Q P++ +  ++ +  KE +  K K    
Sbjct: 761  PAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKV-EWLKNNIRVKESYRIKSKADND 819

Query: 4367 ----QTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRV 4422
                  ++    D+ + + +   +   +  +A    RV   PVKPS    F  K++P   
Sbjct: 820  TATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRV---PVKPS----FVTKLKPTEA 872

Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-LIIRQVFVEDSAVF 4481
             E  +ARF+V+  G P P ++W+     I     F+      +   L++  + + DS   
Sbjct: 873  VEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGTI 932

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTSGQLVRLDTKVTGT 4540
              +A N  G     A+L V+E+       +  P F    Q  + V  G+ + + + V   
Sbjct: 933  KCIATNEAGKVTSRADLNVKER-------LFAPVFEDEEQGPIKVQEGEEISIKSVVKAK 985

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
               DV W+KNGK ++   +  +   D T+ + I  A   DSG+Y C A NS G+    A 
Sbjct: 986  PKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGK----AS 1041

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
               S+   K  PK         P++I  ++   + EG+    +C++ GKP P+V+W K D
Sbjct: 1042 RTYSVEVEKKVPKGHA------PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDD 1095

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-------- 4712
            K +   +        +  TL++ +A  EDE  Y C A NS G V+ +A+L+V        
Sbjct: 1096 KPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPI 1155

Query: 4713 --------------TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
                           +PD+    P +  L D+VV  G+ A+   +IT   KP ++W+++G
Sbjct: 1156 SPEPVSPVFEEPVKAEPDEGTVAPVIEGLNDVVVPLGREAKLDARITGSPKPEVEWIKDG 1215

Query: 4759 ALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQ 4801
             ++ +   F  +      +  L+I +   ED G + C A    G+
Sbjct: 1216 QVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score =  170 bits (413), Expect = 3e-41
 Identities = 127/446 (28%), Positives = 199/446 (44%), Gaps = 48/446 (10%)

Query: 4396 TQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP 4455
            T +  V  PVKPS    F KKM+P    E  +ARF+V+  G P P ++W+R    I +  
Sbjct: 220  TAKLTVNVPVKPS----FVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKE 275

Query: 4456 DFQIH-TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP 4514
             F +  T   +  L+I  +  ED+ VF  VA N  G     A+L V+E++         P
Sbjct: 276  RFHVEETGEDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKERQ-------FAP 328

Query: 4515 SFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
             F       V +  G  + +   +      DV W  NGK ++      I     T++L I
Sbjct: 329  IFEDEQMGPVILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAI 388

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
            + A  +D+G+Y C A N  G+A    +  V   A K             P I+  +K + 
Sbjct: 389  ISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQAPK----------GTAPTILSEMKPQQ 438

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V EG+ +  +C + GKP PTV+W K  K +    + +    A+  TL    A  EDE  Y
Sbjct: 439  VVEGEDVMLACAVSGKPEPTVEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALY 498

Query: 4694 KCVAYNSAGRVTVAAKLKVTQ-PD----------------------QADNLPALTPLRDI 4730
             CVA N+ G V+ +A+L+V + P+                      +    P +  L+D 
Sbjct: 499  TCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALMSKPKDLEKTGAPVIKELKDT 558

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDT 4788
             V  GQ A+   ++T   KP ++W ++G ++ +   F  + +    V  L+I +   ED 
Sbjct: 559  SVPIGQEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDA 618

Query: 4789 GTFTCRATTAAGQVETSAKLVVKSKT 4814
            G + C A    G+VE  A L +K +T
Sbjct: 619  GKYKCIAFNEKGEVEAEANLSIKEET 644



 Score =  165 bits (402), Expect = 6e-40
 Identities = 115/441 (26%), Positives = 189/441 (42%), Gaps = 20/441 (4%)

Query: 4374 GDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVE 4433
            G+ E    ++  E TE   +       V    + + P    K+  P  V E E  R +  
Sbjct: 630  GEVEAEANLSIKEETETAPEKVEPTADVGVKEELTAPKFMDKERGPIEVEEGEDVRLKTR 689

Query: 4434 FDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
              G+P P I+W R    ++ S +  + + + + +L +  V VED+A +  VA N  G A+
Sbjct: 690  VRGQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAE 749

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                L+V+ K   G    V P      Q + V   Q+V+L    T  +   V WLKN  +
Sbjct: 750  QDFELIVKFKAPAG----VAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIR 805

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            V+   R K   ++ T TL I ++  +D G Y+CV  N  G    +A   V +P       
Sbjct: 806  VKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVP------- 858

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                     P  +  LK     EG    F  K+ G P P V+W+ G   I     F+   
Sbjct: 859  -------VKPSFVTKLKPTEAVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRFEE 911

Query: 4674 TADE-YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
              +E ++L +++    D G  KC+A N AG+VT  A L V +   A           I V
Sbjct: 912  VGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFED-EEQGPIKV 970

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
             EG+    K+ + +K K  ++W++ G  + ++    +    +   + I     +D+G +T
Sbjct: 971  QEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYT 1030

Query: 4793 CRATTAAGQVETSAKLVVKSK 4813
            C AT + G+   +  + V+ K
Sbjct: 1031 CEATNSVGKASRTYSVEVEKK 1051



 Score =  160 bits (389), Expect = 2e-38
 Identities = 120/436 (27%), Positives = 191/436 (43%), Gaps = 37/436 (8%)

Query: 4411 PIFT-KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PIF  ++M P  + + ++   +     +P P + WY    P++++P   I +      L 
Sbjct: 328  PIFEDEQMGPVILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLA 387

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I    +ED+  +   A N+ G A  + ++ VEE+  +G      P+     +   V  G+
Sbjct: 388  IISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQAPKGTA----PTILSEMKPQQVVEGE 443

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V L   V+G     V WLK GK +  D   +   E    TL    A  +D   Y CVA 
Sbjct: 444  DVMLACAVSGKPEPTVEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVAT 503

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANA-----PPE-------IIEPLKDKIVAEG 4637
            N+ G     AE  V        P+  T  A       P +       +I+ LKD  V  G
Sbjct: 504  NALGSVSSSAELQVDEKPEISAPESTTPVAETALMSKPKDLEKTGAPVIKELKDTSVPIG 563

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM--SRTADEYTLRISEAFPEDEGDYKC 4695
            Q  +   ++ G P P V+W+K  K+++ +  F        + ++L I +  PED G YKC
Sbjct: 564  QEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKC 623

Query: 4696 VAYNSAGRVTVAAKLKV-----TQPDQADNL------PALTPLR-------DIVVYEGQP 4737
            +A+N  G V   A L +     T P++ +          LT  +        I V EG+ 
Sbjct: 624  IAFNEKGEVEAEANLSIKEETETAPEKVEPTADVGVKEELTAPKFMDKERGPIEVEEGED 683

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
             + KT++  + +P I+WLR G ++ ++ +  M       VL + N   EDT T+TC A  
Sbjct: 684  VRLKTRVRGQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARN 743

Query: 4798 AAGQVETSAKLVVKSK 4813
             AG  E   +L+VK K
Sbjct: 744  EAGMAEQDFELIVKFK 759



 Score =  159 bits (385), Expect = 7e-38
 Identities = 126/494 (25%), Positives = 211/494 (42%), Gaps = 28/494 (5%)

Query: 4328 QTEEVTEQRVQKKVT--QKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITST 4385
            + EE  + R++ +V    +P I       V  K  +V  +   ++ V+  + +  + T+T
Sbjct: 677  EVEEGEDVRLKTRVRGQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTAT 736

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKP----PIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
             T    ++A   E+  E  VK   P    P   + +QP  V E +  +  + F  E  P 
Sbjct: 737  YTCVARNEAGMAEQDFELIVKFKAPAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPK 796

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W + N  +K S   +    +  + L I+Q   ED  V+  V  N  GT    A L V 
Sbjct: 797  VEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVR 856

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
                      V PSF    +      G   R D KV G+   +V W     K+    R +
Sbjct: 857  VP--------VKPSFVTKLKPTEAVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFR 908

Query: 4562 ILEE-DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAAN 4620
              E  +  ++L++ +    DSG  +C+A N AG+    A+  V         K +  A  
Sbjct: 909  FEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNV---------KERLFAPV 959

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
               E   P+K   V EG+ I     +  KP   V+W K  K +K S    +    D + +
Sbjct: 960  FEDEEQGPIK---VQEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNV 1016

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQ 4739
             I  A  +D G+Y C A NS G+ +    ++V +     + P L   +R + + EG+ A 
Sbjct: 1017 TIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAV 1076

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
               ++T K +P+++WL++   +P       ++ G  A L +     ED   +TC A+ + 
Sbjct: 1077 MTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSL 1136

Query: 4800 GQVETSAKLVVKSK 4813
            G V +SA+L V  K
Sbjct: 1137 GSVSSSAELQVDEK 1150



 Score =  150 bits (364), Expect = 2e-35
 Identities = 95/313 (30%), Positives = 151/313 (48%), Gaps = 18/313 (5%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT--YTL 4571
            P F    +++   +G+  +LD  V+    +D  W +  + ++   R  +++++G   ++L
Sbjct: 17   PVFKQPLKDIIAIAGEEAKLDVIVSVGAEVD--WYRGDQAIEDKGRFMLVDDEGEGMFSL 74

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVS---LPATKDKPKPQT-------KAANA 4621
            LI +  P DSG YECVA N+AGE    AE +V+    P  ++K + +T       K +  
Sbjct: 75   LIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASPVPEEKIQEETAPAVEAEKPSEV 134

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
             P I EPLK   V EG      CK  G P PTV+W K +  ++  +  + ++  D   + 
Sbjct: 135  APLITEPLKSLEVPEGATATLECKATGIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIV 194

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I +A   D+G+YKC+  N  G     AKL V  P +   +  + P   I   EG  A+F 
Sbjct: 195  IKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVKPSFVKKMKPSEGI---EGGEARFD 251

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTCRATTAAG 4800
             QI    KP ++W R    I +   F +   G +   L+I +   ED G F C A+  AG
Sbjct: 252  VQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQYSLVIIDLVTEDAGVFKCVASNEAG 311

Query: 4801 QVETSAKLVVKSK 4813
            ++   A L VK +
Sbjct: 312  KITARADLTVKER 324



 Score =  148 bits (359), Expect = 9e-35
 Identities = 113/416 (27%), Positives = 185/416 (44%), Gaps = 31/416 (7%)

Query: 4415 KKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQ 4472
            K+++   V   ++A+ +    G P P ++W+++   ++++  F         +  L+I  
Sbjct: 553  KELKDTSVPIGQEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDD 612

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-----LTAQN----- 4522
            V  ED+  +  +A N  G  +  ANL ++E+       + P +       LTA       
Sbjct: 613  VQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAPEKVEPTADVGVKEELTAPKFMDKE 672

Query: 4523 ---VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP- 4578
               + V  G+ VRL T+V G    ++ WL+NG+ V+    N  +E      +L LE    
Sbjct: 673  RGPIEVEEGEDVRLKTRVRGQPEPEIEWLRNGEVVRKS-ENVNMESTAEQFVLALENVKV 731

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
            +D+  Y CVA N AG A  D E +V   A           A   P+I+EP++   V E Q
Sbjct: 732  EDTATYTCVARNEAGMAEQDFELIVKFKAP----------AGVAPQILEPIQPLEVGEDQ 781

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
             ++ +     +  P V+W K +  +K S   +     D  TL I ++  ED+G Y+CV  
Sbjct: 782  IVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIR 841

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
            N  G V   A L V  P +   +  L P   +   EG  A+F  ++    KP ++W    
Sbjct: 842  NDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAV---EGGEARFDVKVKGSPKPEVEWFSGT 898

Query: 4759 ALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              I E   F+    G     L++ +    D+GT  C AT  AG+V + A L VK +
Sbjct: 899  TKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKER 954



 Score =  146 bits (354), Expect = 4e-34
 Identities = 107/426 (25%), Positives = 182/426 (42%), Gaps = 23/426 (5%)

Query: 4391 EHKAQTQERVVEGPVKPSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449
            E K Q +        KPS+  P+ T+ ++   V E   A  E +  G P P ++W ++N 
Sbjct: 115  EEKIQEETAPAVEAEKPSEVAPLITEPLKSLEVPEGATATLECKATGIPTPTVEWRKDNI 174

Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
             ++     +         ++I+     D   +  + +N  G    +A L V         
Sbjct: 175  RVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVP------ 228

Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGT 4568
              V PSF    +      G   R D ++ G+   DV W +   K+    R  + E  +  
Sbjct: 229  --VKPSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQ 286

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            Y+L+I++   +D+G ++CVA N AG+    A+  V         K +  A     E + P
Sbjct: 287  YSLVIIDLVTEDAGVFKCVASNEAGKITARADLTV---------KERQFAPIFEDEQMGP 337

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            +   I+ +G  +     I  KP P V WY   K ++ +    +    D ++L I  A  E
Sbjct: 338  V---ILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLE 394

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSK 4747
            D G+Y+C A+N  G+      ++V +       P  L+ ++   V EG+       ++ K
Sbjct: 395  DAGEYRCEAHNKLGKALRTYDVRVEEQAPKGTAPTILSEMKPQQVVEGEDVMLACAVSGK 454

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             +PT++WL+EG  +      +  +E   A L   +   ED   +TC AT A G V +SA+
Sbjct: 455  PEPTVEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAE 514

Query: 4808 LVVKSK 4813
            L V  K
Sbjct: 515  LQVDEK 520



 Score =  136 bits (330), Expect = 3e-31
 Identities = 127/520 (24%), Positives = 217/520 (41%), Gaps = 53/520 (10%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG+++   C V    +PT  +EW    KPL   +  +  ++    +L       ED  +Y
Sbjct: 441  EGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALY 498

Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDT 2906
            TC ATN+ GS ++S  L+           + P+  A       AE A ++K +   +  T
Sbjct: 499  TCVATNALGSVSSSAELQVD---------EKPEISAPESTTPVAETALMSKPK--DLEKT 547

Query: 2907 EYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF 2966
              P    +I    +  +  GQ   L+ +V     P+  +EW+ +GKV+E   RF    D 
Sbjct: 548  GAP----VIKELKDTSVPIGQEAKLDARVTGSPKPE--VEWFKDGKVVEDAGRFLYVEDE 601

Query: 2967 GFVTLDLV--DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEK 3024
                  LV  DV   D+G Y C A+N++GE    + +      ++ E T+        EK
Sbjct: 602  EPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANL------SIKEETETAP-----EK 650

Query: 3025 IQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEW 3084
            ++   D   KE      + T   P+F    +  +++ EG+    +  +   G     IEW
Sbjct: 651  VEPTADVGVKE------ELTA--PKFMDKERGPIEVEEGEDVRLKTRV--RGQPEPEIEW 700

Query: 3085 FYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS 3144
              NG+ +  S  +         VL +   K  D+ TY+C A N+ G AE   +L    K+
Sbjct: 701  LRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKA 760

Query: 3145 K-GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
              G  P+    ++ I+ L+ G+    + T+    +   K+EW  N   ++ S RIK+ +D
Sbjct: 761  PAGVAPQI---LEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKAD 817

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIREL 3263
                 L I  ++  D G Y C   N YG   + A +            ++P  + K++  
Sbjct: 818  NDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAML-------TVRVPVKPSFVTKLKPT 870

Query: 3264 ESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFE 3303
            E+++G + +        P   +      TK+ E     FE
Sbjct: 871  EAVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRFE 910



 Score =  134 bits (325), Expect = 1e-30
 Identities = 121/540 (22%), Positives = 224/540 (41%), Gaps = 47/540 (8%)

Query: 72  PIFE-QIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PIFE +        +G     +  +R  P P V+W     PL       +R    T  ++
Sbjct: 328 PIFEDEQMGPVILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLA 387

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRHVSE---- 184
           ++  ++   D GEY C A N+ G+A+ +  V ++ +               + V E    
Sbjct: 388 IISAKLE--DAGEYRCEAHNKLGKALRTYDVRVEEQAPKGTAPTILSEMKPQQVVEGEDV 445

Query: 185 TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRY 244
            +     G    T E  ++ + ++  +        +    TF+   L + +    +    
Sbjct: 446 MLACAVSGKPEPTVEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNA 505

Query: 245 VGESDVQISTEIDR--------SLGPVSPPKIAQKPRN---------SKLQE-----GAD 282
           +G        ++D         S  PV+   +  KP++          +L++     G +
Sbjct: 506 LGSVSSSAELQVDEKPEISAPESTTPVAETALMSKPKDLEKTGAPVIKELKDTSVPIGQE 565

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--TLRVRNTQKSDSGHYTLLA 340
           A+   +++G+P+P V WFK+G+ + ++ +   +        +L + + Q  D+G Y  +A
Sbjct: 566 AKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIA 625

Query: 341 ENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV-KVCQ 399
            N  G +     L+++  TE           T  ++ E    + + E+  AP+F+ K   
Sbjct: 626 FNEKGEVEAEANLSIKEETE-----------TAPEKVEPTADVGVKEELTAPKFMDKERG 674

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
             +V EG+  R   RV G+P PE+ W  N   +R   N   + + +    L + NV + D
Sbjct: 675 PIEVEEGEDVRLKTRVRGQPEPEIEWLRNGEVVRKSENVN-MESTAEQFVLALENVKVED 733

Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           +   TCVARN++G       L V  K    VAP+ +E    L V E + V L        
Sbjct: 734 TATYTCVARNEAGMAEQDFELIVKFKAPAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQ 793

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            P++ W K+ + +  +  ++   D   +TL I +++A D   YQC  +N  G+  + A L
Sbjct: 794 APKVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAML 853



 Score =  124 bits (299), Expect = 2e-27
 Identities = 105/365 (28%), Positives = 160/365 (43%), Gaps = 34/365 (9%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP   + +K  ++ EG+       +    + T  VEW    KPL   S            
Sbjct: 427  APTILSEMKPQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIAT 484

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696
            L   S   ED   YTC A NALG   +S    V  K  I   S  E   P    + +T+ 
Sbjct: 485  LTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEI---SAPESTTP----VAETAL 537

Query: 1697 YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
              +   +D   T APV    +KD  V   Q A  +AR+   G PK  VEW ++G  +E +
Sbjct: 538  MSK--PKDLEKTGAPVIK-ELKDTSVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDA 592

Query: 1757 NRLTTMHDFG--YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH 1814
             R   + D      +L +  V PED+G Y C A NE GE        V+++A+L ++ + 
Sbjct: 593  GRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGE--------VEAEANLSIKEET 644

Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874
            E+A +K++   D      +E++      AP+F+ +  GP ++ EG+    + R+   P+P
Sbjct: 645  ETAPEKVEPTADVGV---KEELT-----APKFMDKERGPIEVEEGEDVRLKTRVRGQPEP 696

Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934
               +EW  NG+V++        +      L +  V  ED+  YTC A N  G A     L
Sbjct: 697  E--IEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFEL 754

Query: 1935 NVQSK 1939
             V+ K
Sbjct: 755  IVKFK 759



 Score =  121 bits (292), Expect = 1e-26
 Identities = 126/485 (25%), Positives = 194/485 (40%), Gaps = 66/485 (13%)

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            V W+ NGKP+++          D  +L ++S   ED+G Y C+A N+LG+A+ +  +RV 
Sbjct: 360  VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRV- 418

Query: 1404 AKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
                   E Q P G                 I+ E   +KP         + V+EG+ V 
Sbjct: 419  -------EEQAPKGTAPT-------------ILSE---MKP---------QQVVEGEDVM 446

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
              C +    +    VEW K G+P++     RP ++     L       ED  +YTC A N
Sbjct: 447  LACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATN 504

Query: 1524 LVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTS 1583
             +G+   S  L      +I          E    L  + K       D   T AP+    
Sbjct: 505  ALGSVSSSAELQVDEKPEISAPESTTPVAET--ALMSKPK-------DLEKTGAPVIK-E 554

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMS 1641
            LK+  +  GQ A  + R+        +VEW+ + K ++   RF   E       +L I  
Sbjct: 555  LKDTSVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDD 612

Query: 1642 CLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHS 1701
              PED+G Y C A N  GE        V ++ ++ ++ + E A  ++    D        
Sbjct: 613  VQPEDAGKYKCIAFNEKGE--------VEAEANLSIKEETETAPEKVEPTADVGV----- 659

Query: 1702 AQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTT 1761
               E +T           I V E +    + R+   G P+  +EWLRNG  +  S  +  
Sbjct: 660  --KEELTAPKFMDKERGPIEVEEGEDVRLKTRVR--GQPEPEIEWLRNGEVVRKSENVNM 715

Query: 1762 MHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKI 1821
                    L ++ V  ED+ TYTC A NE G A     L V+ KA   +  Q    +Q +
Sbjct: 716  ESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKAPAGVAPQILEPIQPL 775

Query: 1822 QQLED 1826
            +  ED
Sbjct: 776  EVGED 780



 Score =  112 bits (269), Expect = 8e-24
 Identities = 141/510 (27%), Positives = 204/510 (40%), Gaps = 84/510 (16%)

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            R D +V+E +  AP+F         LR+G+    +  +     P+  V WY NGK L++ 
Sbjct: 316  RADLTVKERQF-APIFEDEQMGPVILRKGDELSIKETIRAKPKPD--VNWYHNGKPLRSA 372

Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPK 3526
                         L I     ED+GEY C A+N  G+A+ T  ++V        E Q PK
Sbjct: 373  PTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRV--------EEQAPK 424

Query: 3527 GMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVND 3586
                            GT  T+  E +    P+      D++L+   S   E    P   
Sbjct: 425  ----------------GTAPTILSEMK----PQQVVEGEDVMLACAVSGKPE----PT-- 458

Query: 3587 SSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
                VEW   GKPL   S V+   +     L        D  LYTC ATN  G  + S +
Sbjct: 459  ----VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAE 514

Query: 3647 LQVKGRQGIILEPQLPSHFKSGTESIQKLEET--LHKREEITIEDEKPNPPRFTVEIKDN 3704
            LQV  +      P++     S  ES   + ET  + K +++    EK   P    E+KD 
Sbjct: 515  LQVDEK------PEI-----SAPESTTPVAETALMSKPKDL----EKTGAP-VIKELKDT 558

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GFIALDIDYIYA 3762
              VP G     D RV   G P   ++WF +G+      R   + D      +L ID +  
Sbjct: 559  -SVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQP 615

Query: 3763 RDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE 3822
             DAG+Y C A N+ G     A ++   + +   E   P    G K +EL           
Sbjct: 616  EDAGKYKCIAFNEKGEVEAEANLSIKEETETAPEKVEPTADVGVK-EEL----------- 663

Query: 3823 EPIVSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV 3881
                 T PKF+ + +    VEE E VR + RV  + +P+  IEW RNG+++         
Sbjct: 664  -----TAPKFMDKERGPIEVEEGEDVRLKTRVRGQPEPE--IEWLRNGEVVRKSENVNME 716

Query: 3882 YDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                   L +  V  ED+  Y C A N+ G
Sbjct: 717  STAEQFVLALENVKVEDTATYTCVARNEAG 746



 Score =  110 bits (264), Expect = 3e-23
 Identities = 147/576 (25%), Positives = 227/576 (39%), Gaps = 80/576 (13%)

Query: 1295 ARRTKQVR--EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP 1352
            A RT  VR  E      AP     +   + VEG +V L C +    + T  VEW   GKP
Sbjct: 410  ALRTYDVRVEEQAPKGTAPTILSEMKPQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKP 467

Query: 1353 IKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
            +      RP YE +   L   S   ED  +YTC ATN LG   +S  L+V  K ++    
Sbjct: 468  LSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEI---- 523

Query: 1413 QHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVT 1472
               S  E    + +T+   K   +++  T  P  V +     +V  GQ    + +   VT
Sbjct: 524  ---SAPESTTPVAETALMSKPKDLEK--TGAP--VIKELKDTSVPIGQEAKLDAR---VT 573

Query: 1473 DS-NLKVEWFKNGQPVTIGHRFRPIHDF--GYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
             S   +VEWFK+G+ V    RF  + D      +L I D+  ED+G Y C A N  G  E
Sbjct: 574  GSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVE 633

Query: 1530 VSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEI 1589
                L+ +  T        E   E+++   D         V E  T           +E+
Sbjct: 634  AEANLSIKEET--------ETAPEKVEPTADVG-------VKEELTAPKFMDKERGPIEV 678

Query: 1590 KEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGT 1649
            +EG+    + R+    +   ++EW  N + ++        +      L + +   ED+ T
Sbjct: 679  EEGEDVRLKTRVRGQPEP--EIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTAT 736

Query: 1650 YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQ 1709
            YTC A N  G A      IV  K          G  P++  LE     +    +D+++  
Sbjct: 737  YTCVARNEAGMAEQDFELIVKFKAP-------AGVAPQI--LEPIQPLE--VGEDQIVKL 785

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
               FT           QA            PK+  EWL+N + ++ S R+ +  D     
Sbjct: 786  TLTFT---------SEQA------------PKV--EWLKNNIRVKESYRIKSKADNDTAT 822

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829
            L +K    ED G Y C   N+ G   + + L V+            S + K++  E    
Sbjct: 823  LTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPVK-------PSFVTKLKPTEAVEG 875

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYE 1865
             + R DV+V  +  P  +   +G TK++E     +E
Sbjct: 876  GEARFDVKVKGSPKPE-VEWFSGTTKIAEKGRFRFE 910



 Score =  109 bits (262), Expect = 5e-23
 Identities = 97/413 (23%), Positives = 169/413 (40%), Gaps = 18/413 (4%)

Query: 69   PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
            P  P F    K     +GG A+F+ K++G+P P V W      + E  ++     E+ G+
Sbjct: 858  PVKPSFVTKLKPTEAVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRF---EEVGE 914

Query: 129  --VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE-- 184
               SL++  +   D G   C A N+ G+      +  +                 V E  
Sbjct: 915  EQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGE 974

Query: 185  --TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITK 242
              +++           +  +  + +  ++  D  S DD    T +   + +         
Sbjct: 975  EISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEAT 1034

Query: 243  RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
              VG++    S E+++ +     PK+  + R  ++ EG DA    +++G P P V W K+
Sbjct: 1035 NSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKD 1094

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
             + L    +   +      TL+++     D   YT  A N  G + +S  L V+   E  
Sbjct: 1095 DKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVD---EKG 1151

Query: 363  VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
            V     + ++     E   + E  E  +AP  ++   D  V  G+  + D R+TG P PE
Sbjct: 1152 VVPISPEPVSPV--FEEPVKAEPDEGTVAP-VIEGLNDVVVPLGREAKLDARITGSPKPE 1208

Query: 423  VTWFINDRQIRDDYNHKILV--NESGNHALMITNVTLSDSGVVTCVARNKSGE 473
            V W I D Q+ +D    + V   E G  +L+I +V   D+G   C+A N+ GE
Sbjct: 1209 VEW-IKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score =  107 bits (257), Expect = 2e-22
 Identities = 132/512 (25%), Positives = 203/512 (39%), Gaps = 82/512 (16%)

Query: 917  DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTV 976
            D++SIKE        R +P  D    V W  +G+P+ ++  +         +L I S  +
Sbjct: 344  DELSIKE------TIRAKPKPD----VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKL 393

Query: 977  HDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEE 1036
             DAG Y C A+N +G+A        +   D+  E Q P G                T   
Sbjct: 394  EDAGEYRCEAHNKLGKA--------LRTYDVRVEEQAPKG----------------TAPT 429

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096
            +    KP+         ++VEG+       V  + +   TVEW   GK ++  + ++  +
Sbjct: 430  ILSEMKPQ---------QVVEGEDVMLACAVSGKPE--PTVEWLKEGKPLSRDSHVRPKY 478

Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRH 1156
            +     L   S   ED  +YT VA NA G    SA + V+ +  I          E T  
Sbjct: 479  EAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAP-------ESTTP 531

Query: 1157 IEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHN 1216
            + E+  +     +E+     PV  +      P+  G+   L+ R+   G P   VEWF +
Sbjct: 532  VAETALMSKPKDLEK--TGAPVIKELKDTSVPI--GQEAKLDARV--TGSPKPEVEWFKD 585

Query: 1217 GRSVTVGSRFKTYYDF--GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
            G+ V    RF    D      +L I      D G+Y   A N  G     A + + E   
Sbjct: 586  GKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKE--- 642

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQF-SRALHNIETVEGTNVHLECR 1333
                 + E A E+++   D       V+E++T   AP+F  +    IE  EG +V L+ R
Sbjct: 643  -----ETETAPEKVEPTADVG-----VKEELT---APKFMDKERGPIEVEEGEDVRLKTR 689

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            ++  G     +EW  NG+ ++           +   L L +V  ED+  YTC A N+ G 
Sbjct: 690  VR--GQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGM 747

Query: 1394 AVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
            A     L V  K         P  LE IQ LE
Sbjct: 748  AEQDFELIVKFKAP---AGVAPQILEPIQPLE 776



 Score =  105 bits (253), Expect = 7e-22
 Identities = 94/361 (26%), Positives = 154/361 (42%), Gaps = 40/361 (11%)

Query: 781  ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
            ++ EG +      ++   +PT  VEW K+G+P++  S +   +     +L       ED 
Sbjct: 438  QVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDE 495

Query: 841  GSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXX 900
              YT  A N LG   S+A ++V  +  ++A    PE    + +T                
Sbjct: 496  ALYTCVATNALGSVSSSAELQVDEKPEISA----PESTTPVAETALMSKPKDL------- 544

Query: 901  XVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT 960
               E T  P  K  +KD  S+  G  A  +AR+   G     VEW KDG+ VE + R   
Sbjct: 545  ---EKTGAPVIKE-LKDT-SVPIGQEAKLDARVT--GSPKPEVEWFKDGKVVEDAGRFLY 597

Query: 961  FFNFG--YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLE 1018
              +      +L I  V   DAG Y C A+N  G+    ANL+I  + +           E
Sbjct: 598  VEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAP--------E 649

Query: 1019 KIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVE 1078
            K++   D        +EE+     P+F+   +G  ++ EG+    + RV  Q +    +E
Sbjct: 650  KVEPTADVG-----VKEEL---TAPKFMDKERGPIEVEEGEDVRLKTRVRGQPE--PEIE 699

Query: 1079 WYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            W  NG+ +  +  +          L + +V+ ED+  YT VARN AG A+    + V+ +
Sbjct: 700  WLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFK 759

Query: 1139 S 1139
            +
Sbjct: 760  A 760



 Score =  104 bits (250), Expect = 2e-21
 Identities = 78/330 (23%), Positives = 141/330 (42%), Gaps = 36/330 (10%)

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            + E D ++  +     G    P+I +  +  ++ E    +  +  +    P+V W KN  
Sbjct: 747  MAEQDFELIVKFKAPAGVA--PQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNI 804

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
            R+  S + +    ++  TL ++ ++  D G Y         C++ + Y  V S     V 
Sbjct: 805  RVKESYRIKSKADNDTATLTIKQSRAEDQGVYQ--------CVIRNDYGTVHSEAMLTV- 855

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
                             R+ +      P FV   +  +  EG   RFD +V G P PEV 
Sbjct: 856  -----------------RVPVK-----PSFVTKLKPTEAVEGGEARFDVKVKGSPKPEVE 893

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
            WF    +I +    +         +L++T++ L+DSG + C+A N++G+   +  LNV  
Sbjct: 894  WFSGTTKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNV-- 951

Query: 485  KEQVVAPKFV-ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            KE++ AP F  E    + V+EGE + + +     P   + W K+G P+  + ++ + +  
Sbjct: 952  KERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRD 1011

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
                + I  AK  D+  Y C A N  G  +
Sbjct: 1012 DTHNVTIKTAKVDDSGEYTCEATNSVGKAS 1041



 Score =  102 bits (244), Expect = 8e-21
 Identities = 100/429 (23%), Positives = 171/429 (39%), Gaps = 46/429 (10%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W++NGK + ++  +          L I+  K  D+G Y C A NK G+A  +  +   
Sbjct: 360  VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRVE 419

Query: 3142 DKS-KGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            +++ KG  P   + ++  + + +G+     C V     P+  +EW   G+P+   + ++ 
Sbjct: 420  EQAPKGTAPTILSEMKP-QQVVEGEDVMLACAVS--GKPEPTVEWLKEGKPLSRDSHVRP 476

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260
              +     L        D   Y C A N  G   + A +    K     E   P+S   +
Sbjct: 477  KYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKP----EISAPESTTPV 532

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320
             E      A    P          I +++D T +  GQ A  +AR+     P+  VEWF 
Sbjct: 533  AET-----ALMSKPKDLEKTGAPVIKELKD-TSVPIGQEAKLDARVTGSPKPE--VEWFK 584

Query: 3321 NGKKLPHGHRYRTFHD-----FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
            +GK +    R+    D     F +VI D+     E++G+Y+C+A N+ G    +ANL   
Sbjct: 585  DGKVVEDAGRFLYVEDEEPEVFSLVIDDV---QPEDAGKYKCIAFNEKGEVEAEANLSIK 641

Query: 3376 SKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREG 3435
                               E+ +T  + +    D  V+EE   AP F         + EG
Sbjct: 642  -------------------EETETAPEKVEPTADVGVKEEL-TAPKFMDKERGPIEVEEG 681

Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLC 3495
            E+   + R+    +P  ++EW  NG+ ++              +L +     ED+  Y C
Sbjct: 682  EDVRLKTRVRGQPEP--EIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTC 739

Query: 3496 RAYNNYGEA 3504
             A N  G A
Sbjct: 740  VARNEAGMA 748



 Score =  102 bits (244), Expect = 8e-21
 Identities = 104/411 (25%), Positives = 172/411 (41%), Gaps = 37/411 (9%)

Query: 1186 PPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSA 1245
            P  V EG+++ L C +    +PT  VEW   G+ ++  S  +  Y+     L    AT  
Sbjct: 436  PQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLE 493

Query: 1246 DTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDI 1305
            D   YT  A N LGS  +SA ++V E+ +I        A E    + + A  +K   +D+
Sbjct: 494  DEALYTCVATNALGSVSSSAELQVDEKPEI-------SAPESTTPVAETALMSKP--KDL 544

Query: 1306 TVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
                AP   + L +     G    L+ R+   G     VEWF +GK ++   RF    + 
Sbjct: 545  EKTGAPVI-KELKDTSVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDE 601

Query: 1366 DYVALDLL--SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQY 1423
            +     L+   V PED+G Y C A N+ GE        V A+ +L ++ +  +  EK++ 
Sbjct: 602  EPEVFSLVIDDVQPEDAGKYKCIAFNEKGE--------VEAEANLSIKEETETAPEKVEP 653

Query: 1424 LEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN 1483
              D         + E +T  P+F+ + +    V EG+ V  + ++    +   ++EW +N
Sbjct: 654  TADVG-------VKEELTA-PKFMDKERGPIEVEEGEDVRLKTRVRGQPEP--EIEWLRN 703

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            G+ V                L + ++  ED+  YTC A N  G  E    L  +      
Sbjct: 704  GEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKAPAG 763

Query: 1544 RSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
             + Q    ++ ++V ED+          E   QAP       N+ +KE  R
Sbjct: 764  VAPQILEPIQPLEVGEDQIVKLTLTFTSE---QAPKVEWLKNNIRVKESYR 811



 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 57/180 (31%), Positives = 88/180 (48%), Gaps = 3/180 (1%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P FVK  +  +  EG   RFD ++ G P P+V WF    +I D     +       ++L+
Sbjct: 231 PSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQYSLV 290

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVL 510
           I ++   D+GV  CVA N++G+   +  L V  KE+  AP F  E+   + +R+G+ + +
Sbjct: 291 IIDLVTEDAGVFKCVASNEAGKITARADLTV--KERQFAPIFEDEQMGPVILRKGDELSI 348

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  P P + W  +G P+   P L I + G   +L I  AK  DA  Y+C A N  G
Sbjct: 349 KETIRAKPKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLG 408



 Score = 98.3 bits (234), Expect = 1e-19
 Identities = 103/418 (24%), Positives = 164/418 (39%), Gaps = 39/418 (9%)

Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287
            +  R+E + PK + P  ++E++    V EG+     C V    +P   +E+   GK L  
Sbjct: 414  YDVRVEEQAPKGTAPTILSEMK-PQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSR 470

Query: 2288 AARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
             +     ++    +L  +    ED   Y+  A NALG  +S+  + V  K  I +    P
Sbjct: 471  DSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISA----P 526

Query: 2348 EGLEKIRELE-SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDP 2406
            E    + E    ++P    +   PV ++    + P+        GQ A  D R+   G P
Sbjct: 527  ESTTPVAETALMSKPKDLEKTGAPVIKELKDTSVPI--------GQEAKLDARV--TGSP 576

Query: 2407 TLKVEWFRNEKLIEDSSRITKTHDFG--YVSMTISHVRDEDEGVYMCRASNLLGEXXXXX 2464
              +VEWF++ K++ED+ R     D      S+ I  V+ ED G Y C A N  GE     
Sbjct: 577  KPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGE----- 631

Query: 2465 XXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQ 2524
                     I+ ET+        +K+E   +   +E   E   P F     GP E+ EG+
Sbjct: 632  -VEAEANLSIKEETETAP-----EKVEPTADVGVKE---ELTAPKFMDKERGPIEVEEGE 682

Query: 2525 HAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCK 2584
                + RV   G P    EW  NG  ++               L + +V   D   Y C 
Sbjct: 683  DVRLKTRV--RGQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCV 740

Query: 2585 AINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAP 2642
            A N AG                    + P+  E IQ  E   +++ ++ +    +QAP
Sbjct: 741  ARNEAGMAEQDFELIVKFKA---PAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAP 795



 Score = 95.1 bits (226), Expect = 1e-18
 Identities = 100/390 (25%), Positives = 150/390 (38%), Gaps = 34/390 (8%)

Query: 1807 SLQLESQHESALQKIQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYE 1865
            S +LE   E   +   +L  + R Y  R + +     AP  ++++  P ++ EG+     
Sbjct: 390  SAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQAPKGTAPTILSEMK-PQQVVEGEDVMLA 448

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +   P+P   VEW   GK L      R   +   A L   +   ED   YTC A N L
Sbjct: 449  CAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNAL 506

Query: 1926 GQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIK 1985
            G   SS  L V  K  I          E        S+ K   +  + V+      K +K
Sbjct: 507  GSVSSSAELQVDEKPEISAPESTTPVAETALM----SKPKDLEKTGAPVI------KELK 556

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF--GYVALDILYAY 2043
            +  V  G    L+A +T    P   VEW+ +G+ V+   RF    D      +L I    
Sbjct: 557  DTSVPIGQEAKLDARVT--GSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQ 614

Query: 2044 AEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEE 2103
             ED G Y C A N  GE        V+A++ L +    E   +K++          ++EE
Sbjct: 615  PEDAGKYKCIAFNEKGE--------VEAEANLSIKEETETAPEKVEPTADV----GVKEE 662

Query: 2104 QPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD 2163
                 P F+        ++EG+    + RV     P   I+W  NG+ +R          
Sbjct: 663  LTA--PKFMDKERGPIEVEEGEDVRLKTRVR--GQPEPEIEWLRNGEVVRKSENVNMEST 718

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
                 L +     ED+ TY C A N+ G A
Sbjct: 719  AEQFVLALENVKVEDTATYTCVARNEAGMA 748



 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 100/390 (25%), Positives = 159/390 (40%), Gaps = 43/390 (11%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P  +  +K    +EG  +     +    +PT  +EWLK G+ +   S     +     +L
Sbjct: 428  PTILSEMKPQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATL 485

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
               S  ++D   YTC A +A G   + A L V  +  I      PE+   + +    SK 
Sbjct: 486  TFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISA----PESTTPVAETALMSK- 540

Query: 757  QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
               + +E+  +     I+ L+D   +  G+ A  +A++T    P   VEW+KDG+ +  +
Sbjct: 541  --PKDLEKTGA---PVIKELKDT-SVPIGQEAKLDARVT--GSPKPEVEWFKDGKVVEDA 592

Query: 817  SRITSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874
             R   + +      SL I  ++ EDAG Y   A N+ GE  + A++ +    T TA    
Sbjct: 593  GRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSI-KEETETA---- 647

Query: 875  PEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLE 934
            PE+   +E T                 V E    P+F    +  I ++EG     + R+ 
Sbjct: 648  PEK---VEPT-------------ADVGVKEELTAPKFMDKERGPIEVEEGEDVRLKTRVR 691

Query: 935  PIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQAT 994
              G     +EWL++G  V  S  +          L +++V V D   YTC A N  G A 
Sbjct: 692  --GQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAE 749

Query: 995  TSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
                L +  K         P  LE IQ LE
Sbjct: 750  QDFELIVKFK---APAGVAPQILEPIQPLE 776



 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 120/538 (22%), Positives = 204/538 (37%), Gaps = 72/538 (13%)

Query: 66   PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            P   +P I E I +     +    K          P V W +    + E   Y ++    
Sbjct: 761  PAGVAPQILEPI-QPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKE--SYRIKSKAD 817

Query: 126  TGDVSLLIKQIGPGDEGEYTCTARNQYG----EAICSVYIQPEGXXXXXXXXXXXXXYRH 181
                +L IKQ    D+G Y C  RN YG    EA+ +V +  +                 
Sbjct: 818  NDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAVEGGE 877

Query: 182  VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
                V+ K  G+     E    T K+A           +   + F   +L ++   +S T
Sbjct: 878  ARFDVKVK--GSPKPEVEWFSGTTKIAEKGRFRFEEVGE---EQFSL-VLTDLQLTDSGT 931

Query: 242  KRYVGESDV-QISTEIDRSLGP--VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT 298
             + +  ++  ++++  D ++     +P    ++    K+QEG +   +  +   P+  V 
Sbjct: 932  IKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPKADVK 991

Query: 299  WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            W KNG+ L +S+K ++ +  +   + ++  +  DSG YT  A N  G             
Sbjct: 992  WMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVG------------- 1038

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
                         + T   E E+++    K  AP+ +   +   + EG+     C VTG+
Sbjct: 1039 -----------KASRTYSVEVEKKVP---KGHAPKLIAEMRPMQIIEGEDAVMTCEVTGK 1084

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P P V W  +D+ +  D     + N  G  A L +    L D  + TC A N  G  +  
Sbjct: 1085 PEPSVEWLKDDKPLPRDQRLTPMYN--GEVATLKLQKAILEDEALYTCTASNSLGSVSSS 1142

Query: 478  CRLNVIEKEQV------VAPKF----------------VERFSTLNVREGEPVVLNARAV 515
              L V EK  V      V+P F                +E  + + V  G    L+AR  
Sbjct: 1143 AELQVDEKGVVPISPEPVSPVFEEPVKAEPDEGTVAPVIEGLNDVVVPLGREAKLDARIT 1202

Query: 516  GTPTPRITWQKDGVPIIPNPELRIHTDG---GASTLDIPRAKASDAAWYQCTAQNVAG 570
            G+P P + W KDG  ++ +    ++ +    G  +L I   +  DA  Y+C A N  G
Sbjct: 1203 GSPKPEVEWIKDG-QVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKG 1259



 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 3/198 (1%)

Query: 383  IEISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            + + E+  AP F    Q    V EG+       V  +P  +V W  N + ++D     + 
Sbjct: 949  LNVKERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVR 1008

Query: 442  VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK-EQVVAPKFVERFSTL 500
              +   H + I    + DSG  TC A N  G+ +    + V +K  +  APK +     +
Sbjct: 1009 SRDD-THNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPM 1067

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             + EGE  V+     G P P + W KD  P+  +  L    +G  +TL + +A   D A 
Sbjct: 1068 QIIEGEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEAL 1127

Query: 561  YQCTAQNVAGSTATRARL 578
            Y CTA N  GS ++ A L
Sbjct: 1128 YTCTASNSLGSVSSSAEL 1145



 Score = 89.4 bits (212), Expect = 6e-17
 Identities = 91/385 (23%), Positives = 157/385 (40%), Gaps = 35/385 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P     +K  +V EG  V L   ++   +PT  VEW   G+P+ +    +  Y+     L
Sbjct: 428  PTILSEMKPQQVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATL 485

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
                A  ED   Y C ATNA+G   +++ ++VD K     +    +    + E     +P
Sbjct: 486  TFKSATLEDEALYTCVATNALGSVSSSAELQVDEKP----EISAPESTTPVAETALMSKP 541

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
            K +E+      PV      +  ++  G  A  + RV     P   ++WF +G+ +    R
Sbjct: 542  KDLEKT---GAPVIKELKDT--SVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGR 594

Query: 2158 YRTTHDF--GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN 2215
            +    D      +L I     ED+G Y C A N+ GE        V    N+ +  +   
Sbjct: 595  FLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGE--------VEAEANLSIKEETET 646

Query: 2216 GLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLR 2275
              EK+        +  + V+E +++ P+F+ + RG   V EG+    + +V    +P   
Sbjct: 647  APEKVEP------TADVGVKE-ELTAPKFMDKERGPIEVEEGEDVRLKTRVRGQPEP--E 697

Query: 2276 IEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
            IE+  NG+ ++ +   ++        L +++   ED   Y+  A N  G       + V 
Sbjct: 698  IEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVK 757

Query: 2336 AKGSIISESQRPEGLEKIRELESAE 2360
             K         P+ LE I+ LE  E
Sbjct: 758  FKA---PAGVAPQILEPIQPLEVGE 779



 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 113/460 (24%), Positives = 176/460 (38%), Gaps = 72/460 (15%)

Query: 2272 PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS 2331
            P   + +YHNGK L+SA    I       SL I     EDAGEY  +A N LG       
Sbjct: 356  PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYD 415

Query: 2332 MTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEG 2391
            + V        E Q P+G                  P  ++  +P           + EG
Sbjct: 416  VRV--------EEQAPKG----------------TAPTILSEMKP---------QQVVEG 442

Query: 2392 QTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMC 2451
            +     C +    +PT  VEW +  K +   S +   ++    ++T      EDE +Y C
Sbjct: 443  EDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTC 500

Query: 2452 RASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFT 2511
             A+N LG                + E   PE    + +     + +  E   +   P+  
Sbjct: 501  VATNALGSVSSSAELQVDE----KPEISAPESTTPVAETALMSKPKDLE---KTGAPVIK 553

Query: 2512 QVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF--GFVTLD 2569
            ++      +  GQ A  +ARV   G P    EW+ +G  ++   RF    D      +L 
Sbjct: 554  ELKDTSVPI--GQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLV 609

Query: 2570 INSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKV 2629
            I+ V   DAG Y C A N  G                 + +++ E+       E A  KV
Sbjct: 610  IDDVQPEDAGKYKCIAFNEKGEVEAEA-----------NLSIKEET-------ETAPEKV 651

Query: 2630 PEMFVDTGVQQ---APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLT 2686
             E   D GV++   AP F    +   ++ EG+ V L+ +V  R  P  +IEW +NG  + 
Sbjct: 652  -EPTADVGVKEELTAPKFMDKERGPIEVEEGEDVRLKTRV--RGQPEPEIEWLRNGEVVR 708

Query: 2687 TGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
                +          L++ +++ +D+  YTC A N  G A
Sbjct: 709  KSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMA 748



 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 72/318 (22%), Positives = 126/318 (39%), Gaps = 33/318 (10%)

Query: 263 VSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           ++ PK   K R   +++EG D + + ++ G P P + W +NG+ +  S    + +T    
Sbjct: 663 LTAPKFMDKERGPIEVEEGEDVRLKTRVRGQPEPEIEWLRNGEVVRKSENVNMESTAEQF 722

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
            L + N +  D+  YT        C+  +         E+ + +Q  + I   +      
Sbjct: 723 VLALENVKVEDTATYT--------CVARN---------EAGMAEQDFELIVKFK------ 759

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
               +   +APQ ++  Q  +V E ++ +     T    P+V W  N+ ++++ Y  K  
Sbjct: 760 ----APAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSK 815

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
             ++    L I      D GV  CV RN  G    +  L V      V P FV +     
Sbjct: 816 A-DNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV---RVPVKPSFVTKLKPTE 871

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS-TLDIPRAKASDAAW 560
             EG     + +  G+P P + W      I      R    G    +L +   + +D+  
Sbjct: 872 AVEGGEARFDVKVKGSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGT 931

Query: 561 YQCTAQNVAGSTATRARL 578
            +C A N AG   +RA L
Sbjct: 932 IKCIATNEAGKVTSRADL 949



 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 78/333 (23%), Positives = 136/333 (40%), Gaps = 21/333 (6%)

Query: 252 ISTEIDRSLGPVSPPKIAQKPRNSKLQ-EGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
           +  +I+ +  P S   + ++P    +   G +A+  V +S      V W++  Q + +  
Sbjct: 2   VPQKIEDTTAPDSKAPVFKQPLKDIIAIAGEEAKLDVIVSVGAE--VDWYRGDQAIEDKG 59

Query: 311 KHEIITTHNHT--TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
           +  ++        +L + + Q SDSG Y  +A N  G         V S  E  V D  S
Sbjct: 60  RFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAG--------EVSSKAELIVNDGAS 111

Query: 369 QYITDTQQRETEERIEISEKA-LAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
               +  Q ET   +E  + + +AP   +  +  +V EG     +C+ TG P P V W  
Sbjct: 112 PVPEEKIQEETAPAVEAEKPSEVAPLITEPLKSLEVPEGATATLECKATGIPTPTVEWRK 171

Query: 428 NDRQIRDDYNHKILVNESGNH-ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
           ++ ++R+    +I   + G+   ++I +   +D G   C+ +N  G      +L V    
Sbjct: 172 DNIRVRE--GRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV---N 226

Query: 487 QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG-GA 545
             V P FV++       EG     + +  G+P P + W +    I       +   G   
Sbjct: 227 VPVKPSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQ 286

Query: 546 STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +L I      DA  ++C A N AG    RA L
Sbjct: 287 YSLVIIDLVTEDAGVFKCVASNEAGKITARADL 319



 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 87/362 (24%), Positives = 142/362 (39%), Gaps = 36/362 (9%)

Query: 2100 IEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158
            +EE+ P G  P  L+ +   + + EG+     C V     P  T++W   G+ +      
Sbjct: 418  VEEQAPKGTAPTILSEMKP-QQVVEGEDVMLACAVS--GKPEPTVEWLKEGKPLSRDSHV 474

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLE 2218
            R  ++     L       ED   Y C ATN LG   ++  L+V     I      P    
Sbjct: 475  RPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEI----SAPESTT 530

Query: 2219 KIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEF 2278
             + +         +E    K   P  + EL+ T+ V  G+ A  + +V     P   +E+
Sbjct: 531  PVAETALMSKPKDLE----KTGAP-VIKELKDTS-VPIGQEAKLDARV--TGSPKPEVEW 582

Query: 2279 YHNGKALQSAARFHITFDFG--YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
            + +GK ++ A RF    D      SL I    PEDAG+Y   A N  G         V A
Sbjct: 583  FKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGE--------VEA 634

Query: 2337 KGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHF 2396
            + ++  + +     EK+      EP     + E +T   P F    +    ++EG+    
Sbjct: 635  EANLSIKEETETAPEKV------EPTADVGVKEELTA--PKFMDKERGPIEVEEGEDVRL 686

Query: 2397 DCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNL 2456
              R+   G P  ++EW RN +++  S  +          + + +V+ ED   Y C A N 
Sbjct: 687  KTRVR--GQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNE 744

Query: 2457 LG 2458
             G
Sbjct: 745  AG 746



 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 126/523 (24%), Positives = 190/523 (36%), Gaps = 82/523 (15%)

Query: 3405 VRRKDTSVEEE--KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKS 3462
            +R  D  VEE+  KG AP     +   + + EGE+      ++   +P   VEW   GK 
Sbjct: 411  LRTYDVRVEEQAPKGTAPTILSEMKP-QQVVEGEDVMLACAVSGKPEPT--VEWLKEGKP 467

Query: 3463 LKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIIL-E 3521
            L   S  R   +     L       ED   Y C A N  G   ++A ++V  K  I   E
Sbjct: 468  LSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPE 527

Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL 3581
            S  P      + K   LE             ++G P        D  +     A  + R+
Sbjct: 528  STTPVAETALMSKPKDLE-------------KTGAP--VIKELKDTSVPIGQEAKLDARV 572

Query: 3582 IPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI--LEIGGVYQRDAGLYTCKATNRHG 3639
                     VEWF +GK +    R   + D    +  L I  V   DAG Y C A N  G
Sbjct: 573  --TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKG 630

Query: 3640 EATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTV 3699
            E      L +K                   E  +   E +    ++ +++E    P+F  
Sbjct: 631  EVEAEANLSIK-------------------EETETAPEKVEPTADVGVKEEL-TAPKFMD 670

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
            + +  I+V EG  V    RV   G P   I+W  NG        V+  +      L ++ 
Sbjct: 671  KERGPIEVEEGEDVRLKTRVR--GQPEPEIEWLRNGEVVRKSENVNMESTAEQFVLALEN 728

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
            +   D   YTC A N+ G A    ++    K    +  Q+      E I+ LE G     
Sbjct: 729  VKVEDTATYTCVARNEAGMAEQDFELIVKFKAPAGVAPQIL-----EPIQPLEVG----- 778

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
              E+ IV     F       T E++          PK      +EW +N   +   +R +
Sbjct: 779  --EDQIVKLTLTF-------TSEQA----------PK------VEWLKNNIRVKESYRIK 813

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            +  D    +L I    AED G Y C   ND+G   ++A ++ +
Sbjct: 814  SKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVR 856



 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 95/408 (23%), Positives = 165/408 (40%), Gaps = 51/408 (12%)

Query: 3670 ESIQKLEETLHKREEITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTM 3727
            E+  KL + L +  ++ +E++ P    P    E+K    V EG  V   C V    +PT 
Sbjct: 402  EAHNKLGKAL-RTYDVRVEEQAPKGTAPTILSEMKPQ-QVVEGEDVMLACAVSGKPEPT- 458

Query: 3728 RIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC 3787
             ++W   G+P +  S V    +     L        D   YTC ATN  GS +++A++  
Sbjct: 459  -VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQV 517

Query: 3788 SAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGV 3847
              K         P+  + E    +    +   PK+  +  T    I ++K  +V   +  
Sbjct: 518  DEK---------PEISAPESTTPVAETALMSKPKD--LEKTGAPVIKELKDTSVPIGQEA 566

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD--MGFVSLDILYVYAEDSGEYICR 3905
            + + RV     PK  +EW+++GK++    R+  V D      SL I  V  ED+G+Y C 
Sbjct: 567  KLDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCI 624

Query: 3906 AVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLY 3965
            A N+ GE   +A +S K+  +   +   P                   T++V + E+   
Sbjct: 625  AFNEKGEVEAEANLSIKEETETAPEKVEP-------------------TADVGVKEE--- 662

Query: 3966 DVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPI 4025
                   P+F+ + +    + E E  + + ++   G P  ++EW  NG+ +         
Sbjct: 663  ----LTAPKFMDKERGPIEVEEGEDVRLKTRVR--GQPEPEIEWLRNGEVVRKSENVNME 716

Query: 4026 YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDET--KAVIKTTGKPGI 4071
                   +    V  ED+  Y C A N  GM E   + ++K     G+
Sbjct: 717  STAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKAPAGV 764



 Score = 82.6 bits (195), Expect = 7e-15
 Identities = 71/286 (24%), Positives = 125/286 (43%), Gaps = 19/286 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            ++W  NGK ++ S ++          + I   K  DSG Y+C ATN  G+A  +  +E  
Sbjct: 990  VKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVE 1049

Query: 3142 DK-SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
             K  KG  P+    ++ ++ + +G+ A   C V     P+  +EW  + +P+    R+  
Sbjct: 1050 KKVPKGHAPKLIAEMRPMQ-IIEGEDAVMTCEV--TGKPEPSVEWLKDDKPLPRDQRLTP 1106

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260
            + +     L +      D   Y C A N  G   + A +    KG V    + P+ ++ +
Sbjct: 1107 MYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVV---PISPEPVSPV 1163

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320
             E E ++    +    P       I  + DV  +  G+ A  +AR+     P  +VEW  
Sbjct: 1164 FE-EPVKAEPDEGTVAP------VIEGLNDVV-VPLGREAKLDARI--TGSPKPEVEWIK 1213

Query: 3321 NGKKLPHGHR--YRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            +G+ +    R  Y    + GI  L I     E++G+Y+C+A N+ G
Sbjct: 1214 DGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKG 1259



 Score = 82.2 bits (194), Expect = 9e-15
 Identities = 107/462 (23%), Positives = 184/462 (39%), Gaps = 68/462 (14%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA----F 3103
            P F T  K   +  EG  A ++  +   G     +EWF     I    R R        F
Sbjct: 861  PSFVTKLKP-TEAVEGGEARFDVKV--KGSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQF 917

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
             +V+ ++   + TDSGT  C ATN+ G  +++ + +   K +   P F    Q    +++
Sbjct: 918  SLVLTDL---QLTDSGTIKCIATNEAG--KVTSRADLNVKERLFAPVFEDEEQGPIKVQE 972

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+    +  V     P   ++W  NG+P++ S+++   S      + I   +  DSGEY 
Sbjct: 973  GEEISIKSVVKA--KPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYT 1030

Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPK 3283
            C A N  G+     ++    K     +   P  +A++R ++ ++G         + +P  
Sbjct: 1031 CEATNSVGKASRTYSVEVEKK---VPKGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEP 1087

Query: 3284 FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343
             +  ++D   L   Q      RL P+          YNG+               +  L 
Sbjct: 1088 SVEWLKDDKPLPRDQ------RLTPM----------YNGE---------------VATLK 1116

Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDS 3403
            +     E+   Y C A+N LG  S+ A L+   K               G+  +     S
Sbjct: 1117 LQKAILEDEALYTCTASNSLGSVSSSAELQVDEK---------------GVVPISPEPVS 1161

Query: 3404 MVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL 3463
             V  +    E ++G        L+++  +  G  A  +AR+T +  P  +VEW  +G+ +
Sbjct: 1162 PVFEEPVKAEPDEGTVAPVIEGLNDVV-VPLGREAKLDARITGSPKP--EVEWIKDGQVV 1218

Query: 3464 KAGSRFRTF--CDFGFVILEISPTYPEDSGEYLCRAYNNYGE 3503
            +   RF      + G   L I    PED+G+Y C A+N  GE
Sbjct: 1219 EDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 80/302 (26%), Positives = 128/302 (42%), Gaps = 33/302 (10%)

Query: 2944 KIEWYFNGKVLEQGSRFKLTSDFG--FVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            +++WY   + +E   RF L  D G    +L + DV   DSG+Y C A+N  GE       
Sbjct: 45   EVDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEV------ 98

Query: 3002 YCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDIS 3061
              +SK  LI         E  EKIQ  E++      ++P +     P  T   K + ++ 
Sbjct: 99   --SSKAELIVNDGASPVPE--EKIQ--EETAPAVEAEKPSEVA---PLITEPLKSL-EVP 148

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121
            EG  A  E     TG  +  +EW  +   +    RI+T      + + I     TD G Y
Sbjct: 149  EGATATLECKA--TGIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEY 206

Query: 3122 SCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181
             C   N +G    + KL     +   KP F   ++  EG++ G+ A F+  +     PD 
Sbjct: 207  KCMVKNDFGLDYTTAKLTV---NVPVKPSFVKKMKPSEGIEGGE-ARFDVQIKGSPKPD- 261

Query: 3182 KIEWYHNGQPMRHSTRI---KTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
             +EW+     +    R    +T  D +  V++D+      D+G + C A N+ G+   RA
Sbjct: 262  -VEWFRGMTKITDKERFHVEETGEDQYSLVIIDLV---TEDAGVFKCVASNEAGKITARA 317

Query: 3238 TI 3239
             +
Sbjct: 318  DL 319



 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 67/234 (28%), Positives = 113/234 (48%), Gaps = 19/234 (8%)

Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287
            +S  +E + PK   P+ + E+R    + EG+ A   C+V    +P+  +E+  + K L  
Sbjct: 1044 YSVEVEKKVPKGHAPKLIAEMR-PMQIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPR 1100

Query: 2288 AARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
              R    ++    +L +Q  + ED   Y+  A N+LG  +S+  + V  KG ++  S  P
Sbjct: 1101 DQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKG-VVPIS--P 1157

Query: 2348 EGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPT 2407
            E +  + E    EP K    P+  T   PV  + L ++  +  G+ A  D R+   G P 
Sbjct: 1158 EPVSPVFE----EPVKAE--PDEGT-VAPVI-EGLNDVV-VPLGREAKLDARI--TGSPK 1206

Query: 2408 LKVEWFRNEKLIEDSSRI--TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             +VEW ++ +++ED+ R    +  + G  S+ I  V+ ED G Y C A N  GE
Sbjct: 1207 PEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 64/219 (29%), Positives = 99/219 (45%), Gaps = 17/219 (7%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP     ++ ++I EG+ A     +    + +  VEW  ++KPL    R T   N     
Sbjct: 1057 APKLIAEMRPMQIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVAT 1114

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696
            L +   + ED   YTC A N+LG   +S    V  K  + +  +     P     E+  K
Sbjct: 1115 LKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPE-----PVSPVFEEPVK 1169

Query: 1697 YQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
                 A+ +  T APV    + D+ V   + A  +AR+   G PK  VEW+++G  +E +
Sbjct: 1170 -----AEPDEGTVAPVIE-GLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDA 1221

Query: 1757 NRLTTM--HDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
             R   +   + G  +L +  V PED+G Y C A NE GE
Sbjct: 1222 GRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 72/293 (24%), Positives = 121/293 (41%), Gaps = 28/293 (9%)

Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNF 1632
            ++AP+    LK++    G+ A    +L  +     +V+WY  ++ ++   RF   +    
Sbjct: 14   SKAPVFKQPLKDIIAIAGEEA----KLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGE 69

Query: 1633 GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLE 1692
            G  +L I    P DSG Y C A N  GE  +    IV+   S          +P     E
Sbjct: 70   GMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGAS---------PVPEEKIQE 120

Query: 1693 DTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVP 1752
            +T+         EV   AP+ T P+K + V E   A  E +    G P   VEW ++ + 
Sbjct: 121  ETAPAVEAEKPSEV---APLITEPLKSLEVPEGATATLECKA--TGIPTPTVEWRKDNIR 175

Query: 1753 IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
            +    R+ T  D   + + +K     D G Y C   N+ G   T++ L V          
Sbjct: 176  VREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVK----- 230

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYE 1865
               S ++K++  E     + R DV++  +  P  +    G TK+++ +  H E
Sbjct: 231  --PSFVKKMKPSEGIEGGEARFDVQIKGSPKPD-VEWFRGMTKITDKERFHVE 280



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 80/290 (27%), Positives = 122/290 (42%), Gaps = 30/290 (10%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F +P+K+     G     EA L  +      V+WY   + ++   RF    D G    
Sbjct: 17   PVFKQPLKDIIAIAGE----EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGMF 72

Query: 2038 DILY--AYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             +L       D+G Y C A N  GE  + + + V+       D       +KIQE    E
Sbjct: 73   SLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVN-------DGASPVPEEKIQE----E 121

Query: 2096 RPKPIEEEQPGQ-RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
                +E E+P +  P+    L SLE + EG  A  EC+   I  P  T++W  +  ++R 
Sbjct: 122  TAPAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKATGIPTP--TVEWRKDNIRVRE 178

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
            G R +TT D   + + I      D G Y C   N  G    T  L V    N+ +    P
Sbjct: 179  GRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV----NVPV---KP 231

Query: 2215 NGLEKIRQLEA-QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFE 2263
            + ++K++  E  +G   R +V + K SP   V   RG T + + +  H E
Sbjct: 232  SFVKKMKPSEGIEGGEARFDV-QIKGSPKPDVEWFRGMTKITDKERFHVE 280



 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 70/242 (28%), Positives = 104/242 (42%), Gaps = 21/242 (8%)

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            Q+ ED     ++AP F   L     ++ G+    E +++        V+WY   + ++  
Sbjct: 4    QKIEDTTAPDSKAPVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAIEDK 58

Query: 1891 HRYRTSNDFGFAALDILT--VYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
             R+   +D G     +L   V   DSG Y C A NN G+  S   L       I+ D   
Sbjct: 59   GRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGAS 111

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008
                EKIQ  E+ +    AV+ +      P   +P+K+ EV EG    LE   T +  PT
Sbjct: 112  PVPEEKIQ--EETAP---AVEAEKPSEVAPLITEPLKSLEVPEGATATLECKATGIPTPT 166

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
              VEW  +   V++G R KTT D   + + I  A   D G Y C   N  G   TT+ + 
Sbjct: 167  --VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLT 224

Query: 2069 VD 2070
            V+
Sbjct: 225  VN 226



 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 84/379 (22%), Positives = 140/379 (36%), Gaps = 33/379 (8%)

Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
           E + K  AP  +   + + V EG+     C V+G+P P V W    + +  D +H     
Sbjct: 420 EQAPKGTAPTILSEMKPQQVVEGEDVMLACAVSGKPEPTVEWLKEGKPLSRD-SHVRPKY 478

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV- 502
           E+    L   + TL D  + TCVA N  G  +    L V EK ++ AP+     +   + 
Sbjct: 479 EAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALM 538

Query: 503 -------REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR--- 552
                  + G PV+   +    P  +       V   P PE+    DG     D  R   
Sbjct: 539 SKPKDLEKTGAPVIKELKDTSVPIGQEAKLDARVTGSPKPEVEWFKDGKVVE-DAGRFLY 597

Query: 553 AKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXX 612
            +  +   +     +V    A + +            +  L +   T+            
Sbjct: 598 VEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAP--------- 648

Query: 613 XYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEW 672
                 E+  P    G ++ +  P         +   EG  +  +TR+   G P  +IEW
Sbjct: 649 ------EKVEPTADVGVKEELTAPKFMDKERGPIEVEEGEDVRLKTRVR--GQPEPEIEW 700

Query: 673 LKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
           L+NG+ +  S             L + ++ ++D+  YTC A +  G+AE    L V  +A
Sbjct: 701 LRNGEVVRKSENVNMESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDFELIVKFKA 760

Query: 733 TIERTSQHPETLQYIQQLE 751
                   P+ L+ IQ LE
Sbjct: 761 P---AGVAPQILEPIQPLE 776



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 90/357 (25%), Positives = 146/357 (40%), Gaps = 47/357 (13%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            Q+VEG+ + L   V  K +P   +EW   GK L + S  +   +    TL        D 
Sbjct: 438  QVVEGEDVMLACAVSGKPEPT--VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDE 495

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD 3041
             +YTC A N  G   +S+ +    K  +      P+ T  +      E +L  +P     
Sbjct: 496  ALYTCVATNALGSVSSSAELQVDEKPEI----SAPESTTPVA-----ETALMSKPKDL-- 544

Query: 3042 DDTGRPPEFTTVFKDIVDISE--GQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRT 3099
            + TG P     V K++ D S   GQ A  +A +  TG     +EWF +GK +E + R   
Sbjct: 545  EKTGAP-----VIKELKDTSVPIGQEAKLDARV--TGSPKPEVEWFKDGKVVEDAGRFLY 597

Query: 3100 VYAFGMVVLEIL--GTKTTDSGTYSCRATNKWGQAEISVKLECVDKSK------------ 3145
            V      V  ++    +  D+G Y C A N+ G+ E    L   ++++            
Sbjct: 598  VEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAPEKVEPTADV 657

Query: 3146 GQK-----PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            G K     P+F    +    +++G+    +  V     P+ +IEW  NG+ +R S  +  
Sbjct: 658  GVKEELTAPKFMDKERGPIEVEEGEDVRLKTRV--RGQPEPEIEWLRNGEVVRKSENVNM 715

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG---EDFTRATINCYGKGGVYLESLQP 3254
             S     VL +   +  D+  Y C A N+ G   +DF    +      GV  + L+P
Sbjct: 716  ESTAEQFVLALENVKVEDTATYTCVARNEAGMAEQDF-ELIVKFKAPAGVAPQILEP 771



 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 86/361 (23%), Positives = 148/361 (40%), Gaps = 52/361 (14%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            + V+E ++  P F  E +G   V EG+    +  V+    P   +++  NGK L+ +++ 
Sbjct: 949  LNVKE-RLFAPVFEDEEQGPIKVQEGEEISIKSVVKA--KPKADVKWMKNGKPLKDSSKV 1005

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
             +       ++ I+    +D+GEY+ +A N++G  +   S+ V        E + P+G  
Sbjct: 1006 DVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEV--------EKKVPKG-- 1055

Query: 2352 KIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVE 2411
                            P+ +   RP+          I EG+ A   C +   G P   VE
Sbjct: 1056 --------------HAPKLIAEMRPM---------QIIEGEDAVMTCEV--TGKPEPSVE 1090

Query: 2412 WFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXX 2471
            W +++K +    R+T  ++    ++ +     EDE +Y C ASN LG             
Sbjct: 1091 WLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEK 1150

Query: 2472 XXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEAR 2531
              + +    PE +  +   E+P +    EPD     P+   +      L  G+ A  +AR
Sbjct: 1151 GVVPIS---PEPVSPV--FEEPVK---AEPDEGTVAPVIEGLNDVVVPL--GREAKLDAR 1200

Query: 2532 VVPVGDPSLRFEWYINGVELKMGSRFR--TTHDFGFVTLDINSVVANDAGLYMCKAINRA 2589
            +   G P    EW  +G  ++   RF      + G  +L I+ V   DAG Y C A N  
Sbjct: 1201 I--TGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEK 1258

Query: 2590 G 2590
            G
Sbjct: 1259 G 1259



 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 89/378 (23%), Positives = 138/378 (36%), Gaps = 33/378 (8%)

Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLR 2541
            E   K+ K  + ++ R EE   +   P     +  P ++ EG+       V   G P   
Sbjct: 402  EAHNKLGKALRTYDVRVEEQAPKGTAPTILSEMK-PQQVVEGEDVMLACAVS--GKPEPT 458

Query: 2542 FEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXX 2601
             EW   G  L   S  R  ++    TL   S    D  LY C A N  G           
Sbjct: 459  VEWLKEGKPLSRDSHVRPKYEAEIATLTFKSATLEDEALYTCVATNALGSVSSSAELQVD 518

Query: 2602 XXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVY 2661
                I      PES   +   E A+   P+    TG   AP+    LK     + GQ   
Sbjct: 519  EKPEI----SAPESTTPV--AETALMSKPKDLEKTG---APVI-KELKDTSVPI-GQEAK 567

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDDSGIYTCKA 2719
            L+A+V     P  ++EWFK+G  +    R     D    + +L I+ ++ +D+G Y C A
Sbjct: 568  LDARV--TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIA 625

Query: 2720 TNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISH 2779
             N  GE  + A++ I++      E + P +   +G                         
Sbjct: 626  FNEKGEVEAEANLSIKEETETAPEKVEPTA--DVGV-----------KEELTAPKFMDKE 672

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
               I  +EG+++  +  V    +P  +IEW  N + +                L + +  
Sbjct: 673  RGPIEVEEGEDVRLKTRVRGQPEP--EIEWLRNGEVVRKSENVNMESTAEQFVLALENVK 730

Query: 2840 EEDSGIYTCKATNSKGSA 2857
             ED+  YTC A N  G A
Sbjct: 731  VEDTATYTCVARNEAGMA 748



 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 62/220 (28%), Positives = 98/220 (44%), Gaps = 18/220 (8%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP     M+ +++ E + A     +   G P+  VEWL++  P+    RLT M++     
Sbjct: 1057 APKLIAEMRPMQIIEGEDAVMTCEV--TGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVAT 1114

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829
            L ++    ED   YTC A N LG   +S+ L V  K  + +  +  S +      E+  +
Sbjct: 1115 LKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPV-----FEEPVK 1169

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
             +  E     V      I  LN    +  G+ A  + RI   P P   VEW  +G+V++ 
Sbjct: 1170 AEPDEGTVAPV------IEGLNDVV-VPLGREAKLDARITGSPKPE--VEWIKDGQVVED 1220

Query: 1890 GHR--YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
              R  Y  + + G  +L I  V  ED+G+Y C A N  G+
Sbjct: 1221 AGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 64/217 (29%), Positives = 97/217 (44%), Gaps = 20/217 (9%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG--Y 2433
            PVF QPL++I  I  G+ A  D  ++ VG    +V+W+R ++ IED  R     D G   
Sbjct: 17   PVFKQPLKDIIAIA-GEEAKLDV-IVSVG---AEVDWYRGDQAIEDKGRFMLVDDEGEGM 71

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQP 2493
             S+ I  V+  D G+Y C A N  GE              I  +   P   +KIQ+   P
Sbjct: 72   FSLLIDDVQPSDSGMYECVAFNNAGE-------VSSKAELIVNDGASPVPEEKIQEETAP 124

Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
                +E+P      P+ T+ L    E+ EG  A  E +   +  P++  EW  + + ++ 
Sbjct: 125  -AVEAEKPSE--VAPLITEPLKS-LEVPEGATATLECKATGIPTPTV--EWRKDNIRVRE 178

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G R +TT D   + + I   +  D G Y C   N  G
Sbjct: 179  GRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFG 215



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 56/198 (28%), Positives = 91/198 (45%), Gaps = 17/198 (8%)

Query: 2263 ECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG--YVSLDIQHCVPEDAGEYSVKAI 2320
            E +++ +      +++Y   +A++   RF +  D G    SL I    P D+G Y   A 
Sbjct: 33   EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAF 92

Query: 2321 NALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQ 2380
            N  G  +S   +       I+++   P   EKI+E E+A P    E P  V    P+ T+
Sbjct: 93   NNAGEVSSKAEL-------IVNDGASPVPEEKIQE-ETA-PAVEAEKPSEVA---PLITE 140

Query: 2381 PLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISH 2440
            PL++++ + EG TA  +C+    G PT  VEW ++   + +  RI  T D   + + I  
Sbjct: 141  PLKSLE-VPEGATATLECKA--TGIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKD 197

Query: 2441 VRDEDEGVYMCRASNLLG 2458
                D+G Y C   N  G
Sbjct: 198  AIGTDQGEYKCMVKNDFG 215



 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 74/266 (27%), Positives = 114/266 (42%), Gaps = 34/266 (12%)

Query: 3546 DTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR 3605
            DT  P++++   P F     D+I    + A  E +L  +      V+W+   + +    R
Sbjct: 8    DTTAPDSKA---PVFKQPLKDII----AIAGEEAKLDVIVSVGAEVDWYRGDQAIEDKGR 60

Query: 3606 VKTINDFG--FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663
               ++D G     L I  V   D+G+Y C A N  GE  VS K ++    G    P+   
Sbjct: 61   FMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGE--VSSKAELIVNDGASPVPE--- 115

Query: 3664 HFKSGTESIQKLEETLHKREEITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEP 3721
                  E IQ  EET        +E EKP+   P  T  +K +++VPEG     +C+   
Sbjct: 116  ------EKIQ--EETAP-----AVEAEKPSEVAPLITEPLK-SLEVPEGATATLECKA-- 159

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
             G PT  ++W  +      G R+ T  D   + + I      D GEY C   N +G   T
Sbjct: 160  TGIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYT 219

Query: 3782 TAKITCS--AKRDIVLESQLPQGMSG 3805
            TAK+T +   K   V + +  +G+ G
Sbjct: 220  TAKLTVNVPVKPSFVKKMKPSEGIEG 245



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 56/211 (26%), Positives = 99/211 (46%), Gaps = 24/211 (11%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG++    C V    +P+  +EW  ++KPLP   R    ++    +L +     ED  +Y
Sbjct: 1071 EGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALY 1128

Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVE-QAEEARLAKGRRPSVPD 2905
            TC A+NS GS ++S  L+   +K +   +  P      E V+ + +E  +A    P +  
Sbjct: 1129 TCTASNSLGSVSSSAELQ-VDEKGVVPISPEPVSPVFEEPVKAEPDEGTVA----PVIEG 1183

Query: 2906 TEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL--T 2963
                  + ++P+  E +L       + G  +P      ++EW  +G+V+E   RF     
Sbjct: 1184 LN----DVVVPLGREAKL----DARITGSPKP------EVEWIKDGQVVEDAGRFLYVEN 1229

Query: 2964 SDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
             + G  +L + DV   D+G Y C A+N++GE
Sbjct: 1230 EEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 118/488 (24%), Positives = 185/488 (37%), Gaps = 59/488 (12%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +VEWLK+   V+ S RI +  +     LTIK     D G Y C   N  G   + A LT+
Sbjct: 796  KVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV 855

Query: 1002 VTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSA 1061
                        P  + K++  E       R + +VK + KP  +    GT KI E    
Sbjct: 856  RVPVK-------PSFVTKLKPTEAVEGGEARFDVKVKGSPKPE-VEWFSGTTKIAEKGRF 907

Query: 1062 HFEARVEPQ-----SDLTMTVEWYFNGKQITSANRIQTYHD-------FGYVALD----- 1104
             FE   E Q     +DL +T            A ++ +  D       F  V  D     
Sbjct: 908  RFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGP 967

Query: 1105 IASVRAEDSGVYTVVARNAAGEAQ-------LSASMTVETRSSIDTSSI--------HRG 1149
            I     E+  + +VV      + +       L  S  V+ RS  DT ++          G
Sbjct: 968  IKVQEGEEISIKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSG 1027

Query: 1150 LY--EKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDP 1207
             Y  E T  + ++     +   +++ K     +     P  + EG++  + C  E  G P
Sbjct: 1028 EYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAVMTC--EVTGKP 1085

Query: 1208 TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267
               VEW  + + +    R    Y+     L +  A   D   YT  A N LGS  +SA +
Sbjct: 1086 EPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAEL 1145

Query: 1268 RVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTN 1327
            +V E+  +    +    + +           K   ++ TV  AP     L+++    G  
Sbjct: 1146 QVDEKGVVPISPEPVSPVFE--------EPVKAEPDEGTV--APVIE-GLNDVVVPLGRE 1194

Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY--EFDYVALDLLSVYPEDSGVYTC 1385
              L+ R+   G     VEW  +G+ ++   RF      E    +L +  V PED+G Y C
Sbjct: 1195 AKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKC 1252

Query: 1386 QATNQLGE 1393
             A N+ GE
Sbjct: 1253 IAFNEKGE 1260



 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 73/266 (27%), Positives = 110/266 (41%), Gaps = 26/266 (9%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            K E+ T  D K   P F   +KD I +  G     D  V  VG     +DW+   +    
Sbjct: 5    KIEDTTAPDSKA--PVFKQPLKDIIAIA-GEEAKLDVIVS-VG---AEVDWYRGDQAIED 57

Query: 3741 GSRVHTLNDFG--FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
              R   ++D G    +L ID +   D+G Y C A N  G  ++ A++       IV +  
Sbjct: 58   KGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGA 110

Query: 3799 LPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKED 3858
             P  +  EKI+E E     +A K   +    P     +KS  V E      EC+      
Sbjct: 111  SP--VPEEKIQE-ETAPAVEAEKPSEVA---PLITEPLKSLEVPEGATATLECKATGIPT 164

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT--K 3916
            P   +EW ++   +  G R +T  D   + + I      D GEY C   NDFG D+T  K
Sbjct: 165  PT--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAK 222

Query: 3917 ATISCKKLPDIILQNQVPRGMKRSEA 3942
             T++    P  + + +   G++  EA
Sbjct: 223  LTVNVPVKPSFVKKMKPSEGIEGGEA 248



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 81/339 (23%), Positives = 139/339 (41%), Gaps = 50/339 (14%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
            +V EG  + +++ +     P   V+W  NG+P++   +           + I  A  +D+
Sbjct: 969  KVQEGEEISIKSVVKA--KPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDS 1026

Query: 2048 GTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQ 2107
            G Y C+ATN+VG+A  T SV+V+ K                  + K   PK I E +P Q
Sbjct: 1027 GEYTCEATNSVGKASRTYSVEVEKK------------------VPKGHAPKLIAEMRPMQ 1068

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
                         + EG+ A   C V     P  +++W  + + +    R    ++    
Sbjct: 1069 -------------IIEGEDAVMTCEVT--GKPEPSVEWLKDDKPLPRDQRLTPMYNGEVA 1113

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQG 2227
             L +     ED   Y C A+N LG   ++  L+V   + ++     P   E +  +  + 
Sbjct: 1114 TLKLQKAILEDEALYTCTASNSLGSVSSSAELQV-DEKGVV-----PISPEPVSPVFEE- 1166

Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287
               + E +E  ++P   V E      V  G+ A  + ++     P   +E+  +G+ ++ 
Sbjct: 1167 -PVKAEPDEGTVAP---VIEGLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVED 1220

Query: 2288 AARFHI--TFDFGYVSLDIQHCVPEDAGEYSVKAINALG 2324
            A RF      + G  SL I    PEDAG+Y   A N  G
Sbjct: 1221 AGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKG 1259



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 69/262 (26%), Positives = 115/262 (43%), Gaps = 32/262 (12%)

Query: 3275 STPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334
            + P ++ P F   ++D+  +  G+    EA+L  +     +V+W+   + +    R+   
Sbjct: 10   TAPDSKAPVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLV 64

Query: 3335 HDFGIVILDILY--CYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392
             D G  +  +L       +SG YECVA N  G  S+KA L       ++ D   P     
Sbjct: 65   DDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASP----- 112

Query: 3393 GLEKLQTLEDSMVRRKDTSVEEEKGK--APVFTVPLSNIENLREGENAHFEARLTPTDDP 3450
                    E+ +      +VE EK    AP+ T PL ++E + EG  A  E + T    P
Sbjct: 113  ------VPEEKIQEETAPAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKATGIPTP 165

Query: 3451 NLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA-- 3508
               VEW  +   ++ G R +T  D   + + I      D GEY C   N++G   TTA  
Sbjct: 166  T--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKL 223

Query: 3509 SMKVQGKRNIILESQLPKGMEG 3530
            ++ V  K + + + +  +G+EG
Sbjct: 224  TVNVPVKPSFVKKMKPSEGIEG 245



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 59/225 (26%), Positives = 94/225 (41%), Gaps = 25/225 (11%)

Query: 3966 DVDKKQP----PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR 4021
            +V+KK P    P+ + +++    ++E E     C++   G P   VEW  + KPL    R
Sbjct: 1047 EVEKKVPKGHAPKLIAEMRPM-QIIEGEDAVMTCEVT--GKPEPSVEWLKDDKPLPRDQR 1103

Query: 4022 FTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHM 4081
             TP+Y+     +       ED   Y C A+N  G   + A ++   K G+V  S  P   
Sbjct: 1104 LTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEK-GVVPISPEPVSP 1162

Query: 4082 KSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPR 4141
               E ++              E  +    PV   L D V V  G  A+   R+TG PKP 
Sbjct: 1163 VFEEPVK-------------AEPDEGTVAPVIEGLND-VVVPLGREAKLDARITGSPKPE 1208

Query: 4142 VMWLLNGNTIVNGSRYKLTYD---GMYHFDIPKTRQYDTGKIEVI 4183
            V W+ +G  + +  R+    +   G++   I   +  D GK + I
Sbjct: 1209 VEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCI 1253



 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 71/232 (30%), Positives = 99/232 (42%), Gaps = 22/232 (9%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            ++ P F  PLK    I  G+ A  +  V   ++    V+WY   + I    R     D G
Sbjct: 14   SKAPVFKQPLKDIIAIA-GEEAKLDVIVSVGAE----VDWYRGDQAIEDKGRFMLVDDEG 68

Query: 1100 --YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
                +L I  V+  DSG+Y  VA N AGE    A + V   +S           EK +  
Sbjct: 69   EGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASPVPE-------EKIQ-- 119

Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
            EE+    P  + E+ S+  P+  +PL +   V EG    LEC+    G PT  VEW  + 
Sbjct: 120  EETA---PAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKAT--GIPTPTVEWRKDN 173

Query: 1218 RSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              V  G R KT  D   + + I  A   D GEY     N  G  +T+A + V
Sbjct: 174  IRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV 225



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 69/255 (27%), Positives = 109/255 (42%), Gaps = 25/255 (9%)

Query: 1278 DTQNEQAIEQIQLLEDAARR-TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQP 1336
            D   E   E    +  A+R  + +V + +    AP+    +  ++ +EG +  + C +  
Sbjct: 1024 DDSGEYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAVMTCEV-- 1081

Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
             G     VEW  + KP+    R  P Y  +   L L     ED  +YTC A+N LG   +
Sbjct: 1082 TGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSS 1141

Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENV 1456
            S  L+V  +K ++  S  P                 + + +E V  +P   T    IE +
Sbjct: 1142 SAELQV-DEKGVVPISPEP----------------VSPVFEEPVKAEPDEGTVAPVIEGL 1184

Query: 1457 IE-GQHVHFECKLEP-VTDS-NLKVEWFKNGQPVTIGHRFRPI--HDFGYVALDIIDLIA 1511
             +    +  E KL+  +T S   +VEW K+GQ V    RF  +   + G  +L I D+  
Sbjct: 1185 NDVVVPLGREAKLDARITGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQP 1244

Query: 1512 EDSGIYTCRAVNLVG 1526
            ED+G Y C A N  G
Sbjct: 1245 EDAGKYKCIAFNEKG 1259



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 58/198 (29%), Positives = 87/198 (43%), Gaps = 22/198 (11%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E  G     VEWLKD +P+    R+T  +N     L ++   + D   YTC A N++G  
Sbjct: 1080 EVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSV 1139

Query: 994  TTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGP-LKGT 1052
            ++SA L  V +K ++  S  P               S   EE VK       + P ++G 
Sbjct: 1140 SSSAELQ-VDEKGVVPISPEP--------------VSPVFEEPVKAEPDEGTVAPVIEGL 1184

Query: 1053 NKIVE--GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRI--QTYHDFGYVALDIASV 1108
            N +V   G+ A  +AR+         VEW  +G+ +  A R       + G  +L I  V
Sbjct: 1185 NDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDV 1242

Query: 1109 RAEDSGVYTVVARNAAGE 1126
            + ED+G Y  +A N  GE
Sbjct: 1243 QPEDAGKYKCIAFNEKGE 1260



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 61/225 (27%), Positives = 95/225 (42%), Gaps = 24/225 (10%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P+ I  ++ + ++ EG +A    ++T   +P+  VEW KD +P+    R+T ++N    +
Sbjct: 1058 PKLIAEMRPM-QIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVAT 1114

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXX 889
            L +     ED   YT  A N LG   S+A ++V  +  V      PE             
Sbjct: 1115 LKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPIS---PEP------------ 1159

Query: 890  XXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDG 949
                          E T  P  +    + + +  G  A  +AR+   G     VEW+KDG
Sbjct: 1160 VSPVFEEPVKAEPDEGTVAPVIEG--LNDVVVPLGREAKLDARI--TGSPKPEVEWIKDG 1215

Query: 950  RPVEASSRITTFFNF--GYVALTIKSVTVHDAGHYTCRAYNAIGQ 992
            + VE + R     N   G  +L I  V   DAG Y C A+N  G+
Sbjct: 1216 QVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 68/235 (28%), Positives = 101/235 (42%), Gaps = 23/235 (9%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            P+S + P FK P+KD I+I     A  EA+L+ I      V+W +  + +E   R     
Sbjct: 12   PDS-KAPVFKQPLKDIIAI-----AGEEAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVD 65

Query: 963  NFG--YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020
            + G    +L I  V   D+G Y C A+N  G+ ++ A L       I+ +   P   EKI
Sbjct: 66   DEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASPVPEEKI 118

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            Q  E A         EV     P    PLK   ++ EG +A  E +       T TVEW 
Sbjct: 119  QE-ETAPAVEAEKPSEV----APLITEPLKSL-EVPEGATATLECKA--TGIPTPTVEWR 170

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             +  ++    RI+T  D   + + I      D G Y  + +N  G    +A +TV
Sbjct: 171  KDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV 225



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 74/239 (30%), Positives = 105/239 (43%), Gaps = 27/239 (11%)

Query: 1303 EDITV--MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
            ED T    +AP F + L +I  + G    L+  +  VG +   V+W+   + I+   RF 
Sbjct: 7    EDTTAPDSKAPVFKQPLKDIIAIAGEEAKLDV-IVSVGAE---VDWYRGDQAIEDKGRFM 62

Query: 1361 PAYEFDYVALDLL--SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL-ESQHPSG 1417
               +       LL   V P DSG+Y C A N  GE        V +K +LI+ +   P  
Sbjct: 63   LVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGE--------VSSKAELIVNDGASPVP 114

Query: 1418 LEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRP-KSIENVIEGQHVHFECKLEPVTDSNL 1476
             EKIQ  E+T+   + +   E   + P  +T P KS+E V EG     ECK   +     
Sbjct: 115  EEKIQ--EETAPAVEAEKPSE---VAP-LITEPLKSLE-VPEGATATLECKATGIPTPT- 166

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             VEW K+   V  G R +   D   + + I D I  D G Y C   N  G D  + +LT
Sbjct: 167  -VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLT 224



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 18/219 (8%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+ I  ++ +  +EG        +   G P   +EWLK+ + +    R T ++     +L
Sbjct: 1058 PKLIAEMRPMQIIEGEDAVMTCEV--TGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATL 1115

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
             +    ++D   YTC A ++ G   + A L V  +  +  +   PE +  +        +
Sbjct: 1116 KLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPIS---PEPVSPV--------F 1164

Query: 757  QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
            +     E         I  L D+  +  GR A  +A++T    P   VEW KDG+ +  +
Sbjct: 1165 EEPVKAEPDEGTVAPVIEGLNDV-VVPLGREAKLDARIT--GSPKPEVEWIKDGQVVEDA 1221

Query: 817  SRITSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
             R   + N   G  SL I  ++ EDAG Y   A N+ GE
Sbjct: 1222 GRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 59/226 (26%), Positives = 95/226 (42%), Gaps = 18/226 (7%)

Query: 2130 ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKAT 2187
            E +++ I      +DW+   Q I    R+    D G     +L    +  DSG Y C A 
Sbjct: 33   EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAF 92

Query: 2188 NKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTE 2247
            N  GE  +   L       I+ D   P   EKI++  A      +E E+P    P  +TE
Sbjct: 93   NNAGEVSSKAEL-------IVNDGASPVPEEKIQEETAPA----VEAEKPSEVAP-LITE 140

Query: 2248 LRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHC 2307
               +  V EG TA  EC+   +  P   +E+  +   ++   R   T D   + + I+  
Sbjct: 141  PLKSLEVPEGATATLECKATGIPTPT--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDA 198

Query: 2308 VPEDAGEYSVKAINALG--HCTSAISMTVTAKGSIISESQRPEGLE 2351
            +  D GEY     N  G  + T+ +++ V  K S + + +  EG+E
Sbjct: 199  IGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVKPSFVKKMKPSEGIE 244



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 66/236 (27%), Positives = 97/236 (41%), Gaps = 18/236 (7%)

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
            S  Y    + +V    AP+ I ++  P ++ EG+ A   C +   P+P+  VEW  + K 
Sbjct: 1041 SRTYSVEVEKKVPKGHAPKLIAEMR-PMQIIEGEDAVMTCEVTGKPEPS--VEWLKDDKP 1097

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946
            L    R     +   A L +     ED   YTC A N+LG   SS  L V  K  +    
Sbjct: 1098 LPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISP 1157

Query: 1947 QHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND 2006
            +  S +      E+     +A  D+  V   P   + + +  V  G    L+A +T    
Sbjct: 1158 EPVSPV-----FEEP---VKAEPDEGTVA--PVI-EGLNDVVVPLGREAKLDARIT--GS 1204

Query: 2007 PTMRVEWYCNGRPVQQGHRF--KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGE 2060
            P   VEW  +G+ V+   RF      + G  +L I     ED G Y C A N  GE
Sbjct: 1205 PKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 69/248 (27%), Positives = 99/248 (39%), Gaps = 25/248 (10%)

Query: 3404 MVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL 3463
            MV +K         KAPVF  PL +I  +  GE    EA+L        +V+WY   +++
Sbjct: 1    MVPQKIEDTTAPDSKAPVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAI 55

Query: 3464 KAGSRFRTFCDFG--FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILE 3521
            +   RF    D G     L I    P DSG Y C A+NN GE  + A + V    + + E
Sbjct: 56   EDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASPVPE 115

Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL 3581
             ++    E T   + A             E  S   P  T     L + E ++A  EC+ 
Sbjct: 116  EKI---QEETAPAVEA-------------EKPSEVAPLITEPLKSLEVPEGATATLECKA 159

Query: 3582 IPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA 3641
              +   +  VEW  +   +  G R+KT  D   + + I      D G Y C   N  G  
Sbjct: 160  TGI--PTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLD 217

Query: 3642 TVSCKLQV 3649
              + KL V
Sbjct: 218  YTTAKLTV 225



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 67/261 (25%), Positives = 109/261 (41%), Gaps = 23/261 (8%)

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHST 3196
            K+E       + P F   +++I  +  G+ A  +  +V V     +++WY   Q +    
Sbjct: 5    KIEDTTAPDSKAPVFKQPLKDIIAIA-GEEAKLD-VIVSVG---AEVDWYRGDQAIEDKG 59

Query: 3197 RIKTVSDFG--FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254
            R   V D G     L I   Q  DSG Y C A+N  GE  ++A +       +  +   P
Sbjct: 60   RFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASP 112

Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314
                KI+E E+    + + PS    E    IT+     ++ EG +A  E +   +  P  
Sbjct: 113  VPEEKIQE-ETAPAVEAEKPS----EVAPLITEPLKSLEVPEGATATLECKATGIPTPT- 166

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL-- 3372
             VEW  +  ++  G R +T  D   + + I      + GEY+C+  N  G D T A L  
Sbjct: 167  -VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV 225

Query: 3373 KCTSKENLILDSQLPRGMEGG 3393
                K + +   +   G+EGG
Sbjct: 226  NVPVKPSFVKKMKPSEGIEGG 246



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 73/289 (25%), Positives = 118/289 (40%), Gaps = 36/289 (12%)

Query: 3039 QPDDDTGRPPEFTTVFKD-IVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRI 3097
            Q  +DT  P     VFK  + DI    IA  EA L         ++W+   + IE   R 
Sbjct: 4    QKIEDTTAPDSKAPVFKQPLKDIIA--IAGEEAKLDVIVSVGAEVDWYRGDQAIEDKGRF 61

Query: 3098 RTV--YAFGMVVLEILGTKTTDSGTYSCRATNKWGQ----AEISV----------KLE-- 3139
              V     GM  L I   + +DSG Y C A N  G+    AE+ V          K++  
Sbjct: 62   MLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASPVPEEKIQEE 121

Query: 3140 ---CVDKSKGQK--PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
                V+  K  +  P  T  ++++E + +G +A  EC    +  P   +EW  +   +R 
Sbjct: 122  TAPAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKATGIPTPT--VEWRKDNIRVRE 178

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQP 3254
              RIKT  D   + + I      D GEY C   N +G D+T A +            ++P
Sbjct: 179  GRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVN-------VPVKP 231

Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFE 3303
              + K++  E ++G + +        P   +   + +TK+ + +  H E
Sbjct: 232  SFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVE 280



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 57/219 (26%), Positives = 95/219 (43%), Gaps = 18/219 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+ +   + ++ +IEG+     C++    + +  VEW K+ +P+    R  P+++     
Sbjct: 1058 PKLIAEMRPMQ-IIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVAT 1114

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L +   I ED  +YTC A N +G+   S  L       +  S +  +      V E+  K
Sbjct: 1115 LKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVS-----PVFEEPVK 1169

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
                   DE T  AP+    L +V +  G+ A  + R+        +VEW  + + ++  
Sbjct: 1170 AE----PDEGTV-APV-IEGLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDA 1221

Query: 1624 SRF--TETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
             RF   E    G  +L I    PED+G Y C A N  GE
Sbjct: 1222 GRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 67/243 (27%), Positives = 101/243 (41%), Gaps = 24/243 (9%)

Query: 625 IPPGEEDRVYPP---PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEA 681
           +P   ED   P    P F  PLK + A+ G     E +++ +     +++W +  Q+IE 
Sbjct: 2   VPQKIEDTTAPDSKAPVFKQPLKDIIAIAGE----EAKLDVIVSVGAEVDWYRGDQAIED 57

Query: 682 SSRFTSIFRFGYISLDMLSLNIQ--DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQ 739
             RF  +   G     +L  ++Q  DSG Y C A +  G   +KA L V   A     S 
Sbjct: 58  KGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGA-----SP 112

Query: 740 HPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSD 799
            PE  + IQ+     +       E+ +   P    PL+ L E+ EG  A  E + T +  
Sbjct: 113 VPE--EKIQE-----ETAPAVEAEKPSEVAPLITEPLKSL-EVPEGATATLECKATGIPT 164

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           PT  VEW KD   +    RI +  +   + + I      D G Y     N  G   +TA 
Sbjct: 165 PT--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAK 222

Query: 860 IRV 862
           + V
Sbjct: 223 LTV 225



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 61/229 (26%), Positives = 96/229 (41%), Gaps = 22/229 (9%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG--F 2565
            P+F Q L     +  G+ A  +  +V VG      +WY     ++   RF    D G   
Sbjct: 17   PVFKQPLKDIIAI-AGEEAKLDV-IVSVG---AEVDWYRGDQAIEDKGRFMLVDDEGEGM 71

Query: 2566 VTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAA 2625
             +L I+ V  +D+G+Y C A N AG               I++    P   E+IQ + A 
Sbjct: 72   FSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASPVPEEKIQEETA- 123

Query: 2626 MNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL 2685
                P +  +   + AP+ T  LKS + + EG    LE +      P   +EW K+ + +
Sbjct: 124  ----PAVEAEKPSEVAPLITEPLKSLE-VPEGATATLECKATGIPTPT--VEWRKDNIRV 176

Query: 2686 TTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
              G R+K+T D   + + I      D G Y C   N  G   +TA + +
Sbjct: 177  REGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTV 225



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 59/246 (23%), Positives = 101/246 (41%), Gaps = 21/246 (8%)

Query: 3669 TESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMR 3728
            T S+ K   T     E  +   K + P+   E++  + + EG      C V   G P   
Sbjct: 1034 TNSVGKASRTYSVEVEKKVP--KGHAPKLIAEMRP-MQIIEGEDAVMTCEV--TGKPEPS 1088

Query: 3729 IDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            ++W  + +P     R+  + +     L +      D   YTC A+N  GS +++A++   
Sbjct: 1089 VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVD 1148

Query: 3789 AKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVR 3848
             K        +P  +S E +  +      +  K EP   T    I  +    V      +
Sbjct: 1149 EK------GVVP--ISPEPVSPV----FEEPVKAEPDEGTVAPVIEGLNDVVVPLGREAK 1196

Query: 3849 FECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV--YDMGFVSLDILYVYAEDSGEYICRA 3906
             + R+     PK  +EW ++G+++    R+  V   + G  SL I  V  ED+G+Y C A
Sbjct: 1197 LDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIA 1254

Query: 3907 VNDFGE 3912
             N+ GE
Sbjct: 1255 FNEKGE 1260



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 99/400 (24%), Positives = 153/400 (38%), Gaps = 47/400 (11%)

Query: 760  ESIEEQT---SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
            + IE+ T   S+ P F +PL+D+  +     A  EA+L  +      V+WY+  + I   
Sbjct: 4    QKIEDTTAPDSKAPVFKQPLKDIIAI-----AGEEAKLDVIVSVGAEVDWYRGDQAIEDK 58

Query: 817  SRITSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874
             R   + + G    SL I  ++  D+G Y   A N  GE  S A + V   ++      +
Sbjct: 59   GRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVNDGASP-----V 113

Query: 875  PEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLE 934
            PE++   E+T                    S   P    P+K  + + EG  A  E +  
Sbjct: 114  PEEKIQ-EETAPAVEAEK-----------PSEVAPLITEPLKS-LEVPEGATATLECKAT 160

Query: 935  PIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQAT 994
             I   T  VEW KD   V    RI T  +   + + IK     D G Y C   N  G   
Sbjct: 161  GIPTPT--VEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDY 218

Query: 995  TSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNK 1054
            T+A LT+            P  ++K++  E       R + ++K + KP  +   +G  K
Sbjct: 219  TTAKLTVNV-------PVKPSFVKKMKPSEGIEGGEARFDVQIKGSPKPD-VEWFRGMTK 270

Query: 1055 IVEGQSAHFEARVEPQ-----SDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVR 1109
            I + +  H E   E Q      DL       F       A +I    D        A + 
Sbjct: 271  ITDKERFHVEETGEDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKERQFAPI- 329

Query: 1110 AEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRG 1149
             ED  +  V+ R   G+ +LS   T+  +   D +  H G
Sbjct: 330  FEDEQMGPVILRK--GD-ELSIKETIRAKPKPDVNWYHNG 366



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 48/189 (25%), Positives = 81/189 (42%), Gaps = 14/189 (7%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA----F 3103
            P F    K    I  G+ A ++  +   G     +EWF     I    R          +
Sbjct: 231  PSFVKKMKPSEGIEGGE-ARFDVQI--KGSPKPDVEWFRGMTKITDKERFHVEETGEDQY 287

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
             +V+++++   T D+G + C A+N+ G+  I+ + +   K +   P F         L+ 
Sbjct: 288  SLVIIDLV---TEDAGVFKCVASNEAGK--ITARADLTVKERQFAPIFEDEQMGPVILRK 342

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G     + T+     PD  + WYHNG+P+R +  +   S      L I   +  D+GEY 
Sbjct: 343  GDELSIKETIRAKPKPD--VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYR 400

Query: 3224 CRAYNKYGE 3232
            C A+NK G+
Sbjct: 401  CEAHNKLGK 409



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 46/205 (22%), Positives = 87/205 (42%), Gaps = 15/205 (7%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            +++EG+   +  +V  + +P+  +EW K+   L    RL   ++  + TL +     +D 
Sbjct: 1068 QIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDE 1125

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXX 2772
             +YTC A+N LG   S+A ++++++  +    + P+ +  +                   
Sbjct: 1126 ALYTCTASNSLGSVSSSAELQVDEKGVV---PISPEPVSPV------FEEPVKAEPDEGT 1176

Query: 2773 XXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTR--YKSTHDFSY 2830
                I  LN++V   G     +  +  S  P  ++EW  + + +    R  Y    +   
Sbjct: 1177 VAPVIEGLNDVVVPLGREAKLDARITGSPKP--EVEWIKDGQVVEDAGRFLYVENEEPGI 1234

Query: 2831 VSLDITHTYEEDSGIYTCKATNSKG 2855
             SL I     ED+G Y C A N KG
Sbjct: 1235 FSLVIDDVQPEDAGKYKCIAFNEKG 1259



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 103/390 (26%), Positives = 161/390 (41%), Gaps = 64/390 (16%)

Query: 3392 GGLEKLQTLEDSMVR-RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDP 3450
            G ++ + T E   V  R D +V+E    APVF         ++EGE    ++ +     P
Sbjct: 930  GTIKCIATNEAGKVTSRADLNVKERLF-APVFEDEEQGPIKVQEGEEISIKSVVKAK--P 986

Query: 3451 NLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASM 3510
               V+W  NGK LK  S+           + I     +DSGEY C A N+ G+A  T S+
Sbjct: 987  KADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSV 1046

Query: 3511 KVQGKRNIILESQLPKG-MEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLIL 3569
            +V        E ++PKG     I ++  ++   G    +T E  +G P      PS   L
Sbjct: 1047 EV--------EKKVPKGHAPKLIAEMRPMQIIEGEDAVMTCEV-TGKP-----EPSVEWL 1092

Query: 3570 SENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGL 3629
             ++     + RL P+          +NG+       V T+      ILE   +Y      
Sbjct: 1093 KDDKPLPRDQRLTPM----------YNGE-------VATLK-LQKAILEDEALY------ 1128

Query: 3630 YTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIED 3689
             TC A+N  G  + S +LQV  +  + + P          E +  + E   K E     D
Sbjct: 1129 -TCTASNSLGSVSSSAELQVDEKGVVPISP----------EPVSPVFEEPVKAE----PD 1173

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLN 3748
            E    P   +E  +++ VP G     D R+   G P   ++W  +G+      R ++  N
Sbjct: 1174 EGTVAP--VIEGLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVEN 1229

Query: 3749 DF-GFIALDIDYIYARDAGEYTCRATNKWG 3777
            +  G  +L ID +   DAG+Y C A N+ G
Sbjct: 1230 EEPGIFSLVIDDVQPEDAGKYKCIAFNEKG 1259



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 63/247 (25%), Positives = 103/247 (41%), Gaps = 23/247 (9%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG--F 1234
            PVF QPL +   ++ G+    E +L+ +      V+W+   +++    RF    D G   
Sbjct: 17   PVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGM 71

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDA 1294
             +L I     +D+G Y   A N+ G   + A +       IV D  +    E+IQ  E+ 
Sbjct: 72   FSLLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASPVPEEKIQ--EET 122

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            A   +  +       AP  +  L ++E  EG    LEC+    G  T  VEW  +   ++
Sbjct: 123  APAVEAEKPSEV---APLITEPLKSLEVPEGATATLECKA--TGIPTPTVEWRKDNIRVR 177

Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV-IAKKDLILESQ 1413
             G R +   + D + + +      D G Y C   N  G   T+  L V +  K   ++  
Sbjct: 178  EGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVKPSFVKKM 237

Query: 1414 HPS-GLE 1419
             PS G+E
Sbjct: 238  KPSEGIE 244



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 50/217 (23%), Positives = 94/217 (43%), Gaps = 16/217 (7%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+    ++  ++ EG    +   +T   +P+  VEW  + +P+ +  R    Y+     L
Sbjct: 1058 PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVATL 1115

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             +  A  ED   Y C A+N++G   +++ ++VD K    +  +  + +  +     +E P
Sbjct: 1116 KLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKG---VVPISPEPVSPV-----FEEP 1167

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
               E ++    PV +  L  +  +  G  A  + R+     P   ++W  +GQ +    R
Sbjct: 1168 VKAEPDEGTVAPV-IEGLNDVV-VPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGR 1223

Query: 2158 --YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE 2192
              Y    + G  +L I     ED+G Y C A N+ GE
Sbjct: 1224 FLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 58/238 (24%), Positives = 92/238 (38%), Gaps = 38/238 (15%)

Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            R ++ ++ E+   P F  E +  I V EG  +     V+    P   + W  NG+P    
Sbjct: 946  RADLNVK-ERLFAPVFEDEEQGPIKVQEGEEISIKSVVK--AKPKADVKWMKNGKPLKDS 1002

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801
            S+V   +      + I      D+GEYTC ATN  G A        S    + +E ++P+
Sbjct: 1003 SKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKA--------SRTYSVEVEKKVPK 1054

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861
            G +                         PK I +++   + E E     C V  K +P  
Sbjct: 1055 GHA-------------------------PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPS- 1088

Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             +EW ++ K LP   R   +Y+    +L +     ED   Y C A N  G   + A +
Sbjct: 1089 -VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTASNSLGSVSSSAEL 1145



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 73/270 (27%), Positives = 114/270 (42%), Gaps = 44/270 (16%)

Query: 1934 LNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGH 1993
            L +  K++I  D      + K  +  D +  K  V     V  KP F K +K +E  EG 
Sbjct: 191  LRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVN----VPVKPSFVKKMKPSEGIEGG 246

Query: 1994 PVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF--KTTYDFGYVALDILYAYAEDTGTYM 2051
                +  +     P   VEW+     +    RF  + T +  Y +L I+    ED G + 
Sbjct: 247  EARFDVQIK--GSPKPDVEWFRGMTKITDKERFHVEETGEDQY-SLVIIDLVTEDAGVFK 303

Query: 2052 CKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVF 2111
            C A+N  G        K+ A++ L   T+ E++   I            E+EQ G  PV 
Sbjct: 304  CVASNEAG--------KITARADL---TVKERQFAPI-----------FEDEQMG--PVI 339

Query: 2112 LTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDI 2171
            L     L ++KE  RA           P   ++W+HNG+ +R+             +L I
Sbjct: 340  LRKGDEL-SIKETIRAK----------PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAI 388

Query: 2172 LYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +    ED+G Y C+A NKLG+A+ T  ++V
Sbjct: 389  ISAKLEDAGEYRCEAHNKLGKALRTYDVRV 418



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 29/97 (29%), Positives = 55/97 (56%), Gaps = 2/97 (2%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP+F    +   K+ EG+ + +++ V+ +  P   ++W KNG  L   +++         
Sbjct: 957  APVFEDEEQGPIKVQEGEEISIKSVVKAK--PKADVKWMKNGKPLKDSSKVDVRSRDDTH 1014

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             ++I + + DDSG YTC+ATN +G+A  T S+++E +
Sbjct: 1015 NVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKK 1051



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 63/279 (22%), Positives = 106/279 (37%), Gaps = 22/279 (7%)

Query: 2629 VPEMFVDTGV--QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLT 2686
            VP+   DT     +AP+F   LK    +  G+    EA+++       +++W++    + 
Sbjct: 2    VPQKIEDTTAPDSKAPVFKQPLKDIIAIA-GE----EAKLDVIVSVGAEVDWYRGDQAIE 56

Query: 2687 TGARLKSTFDFG--LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGES 2744
               R     D G  + +L I+ ++  DSG+Y C A N  GE  S A + + D     G S
Sbjct: 57   DKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELIVND-----GAS 111

Query: 2745 LHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPT 2804
              P+       +                  +    L ++   EG     EC  + +  PT
Sbjct: 112  PVPEE-----KIQEETAPAVEAEKPSEVAPLITEPLKSLEVPEGATATLEC--KATGIPT 164

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
              +EW  +N  +  G R K+T D   + + I      D G Y C   N  G   T+  L 
Sbjct: 165  PTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLT 224

Query: 2865 CTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
                    F  +  +   G+E  E   + ++    +P V
Sbjct: 225  VNVPVKPSF-VKKMKPSEGIEGGEARFDVQIKGSPKPDV 262



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 3/115 (2%)

Query: 1826 DSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            ++ +   R D+ V   Q AP F  +  GP  L +G     +  I   P P+  V WY NG
Sbjct: 309  EAGKITARADLTVKERQFAPIFEDEQMGPVILRKGDELSIKETIRAKPKPD--VNWYHNG 366

Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            K L+S       +     +L I++   ED+GEY C+A N LG+A+ +  + V+ +
Sbjct: 367  KPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQ 421



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 3/126 (2%)

Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPD 1873
            +S   K     ++ +   R D+ V     AP F  +  GP K+ EG+    +  ++  P 
Sbjct: 928  DSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPK 987

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
             +  V+W  NGK L+   +    +      + I T   +DSGEYTC+A N++G+A  +  
Sbjct: 988  AD--VKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYS 1045

Query: 1934 LNVQSK 1939
            + V+ K
Sbjct: 1046 VEVEKK 1051



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 22/227 (9%)

Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475
            KG AP     +  ++ + EGE+A     +T   +P+  VEW  + K L    R     + 
Sbjct: 1054 KGHAPKLIAEMRPMQII-EGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNG 1110

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKI 3535
                L++     ED   Y C A N+ G   ++A ++V  K  + +    P+ +    ++ 
Sbjct: 1111 EVATLKLQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPIS---PEPVSPVFEEP 1167

Query: 3536 AALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH 3595
               E   GTV    P  E  N         D+++     A  + R+         VEW  
Sbjct: 1168 VKAEPDEGTV---APVIEGLN---------DVVVPLGREAKLDARI--TGSPKPEVEWIK 1213

Query: 3596 NGKPLLTGSRVKTI--NDFGFVILEIGGVYQRDAGLYTCKATNRHGE 3640
            +G+ +    R   +   + G   L I  V   DAG Y C A N  GE
Sbjct: 1214 DGQVVEDAGRFLYVENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 50/172 (29%), Positives = 70/172 (40%), Gaps = 18/172 (10%)

Query: 3994 ECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG--YVAMNFGWVYPEDSGEYLCRAT 4051
            E +L  +     +V+W+   + +  K RF  + D G    ++    V P DSG Y C A 
Sbjct: 33   EAKLDVIVSVGAEVDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAF 92

Query: 4052 NLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPP 4111
            N  G   +KA +       IV D   P      EKI+E       T   V  E  +   P
Sbjct: 93   NNAGEVSSKAEL-------IVNDGASPVPE---EKIQEE------TAPAVEAEKPSEVAP 136

Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            +      ++ V EG  A   C+ TG P P V W  +   +  G R K T DG
Sbjct: 137  LITEPLKSLEVPEGATATLECKATGIPTPTVEWRKDNIRVREGRRIKTTQDG 188



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 30/105 (28%), Positives = 57/105 (54%), Gaps = 6/105 (5%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEA--RLEPIGDSTLRVEWLKDGRPVEASSRIT 959
            V E    P F+   +  I ++EG     ++  + +P  D    V+W+K+G+P++ SS++ 
Sbjct: 951  VKERLFAPVFEDEEQGPIKVQEGEEISIKSVVKAKPKAD----VKWMKNGKPLKDSSKVD 1006

Query: 960  TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                     +TIK+  V D+G YTC A N++G+A+ + ++ +  K
Sbjct: 1007 VRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKK 1051



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 85/333 (25%), Positives = 133/333 (39%), Gaps = 69/333 (20%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS--DFGFVTLDLVDVYERDSG 2982
            EG+ + ++  V+ K   D+K  W  NGK L+  S+  + S  D   VT+    V   DSG
Sbjct: 972  EGEEISIKSVVKAKPKADVK--WMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKV--DDSG 1027

Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDD 3042
             YTC+A N  G+A   S  Y    +  + +   PK    +  +Q +E     E      +
Sbjct: 1028 EYTCEATNSVGKA---SRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEG----EDAVMTCE 1080

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
             TG+P       KD   +   Q       L P           YNG+   A+ +++    
Sbjct: 1081 VTGKPEPSVEWLKDDKPLPRDQ------RLTP----------MYNGEV--ATLKLQ---- 1118

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS------KGQKPRFTTHIQ 3156
                +LE       D   Y+C A+N  G    S +L+  +K       +   P F   ++
Sbjct: 1119 --KAILE-------DEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPVFEEPVK 1169

Query: 3157 N----------IEGLKD-----GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
                       IEGL D     G+ A  +  +     P  ++EW  +GQ +  + R   V
Sbjct: 1170 AEPDEGTVAPVIEGLNDVVVPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYV 1227

Query: 3202 --SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
               + G   L I   Q  D+G+Y C A+N+ GE
Sbjct: 1228 ENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 3/101 (2%)

Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT-SIFR 690
           RV   P F+  LK   A+EGG+  F+ +++  G P  ++EW      I    RF      
Sbjct: 856 RVPVKPSFVTKLKPTEAVEGGEARFDVKVK--GSPKPEVEWFSGTTKIAEKGRFRFEEVG 913

Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
               SL +  L + DSG   C A +  G   ++A L+V  R
Sbjct: 914 EEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKER 954



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 53/212 (25%), Positives = 88/212 (41%), Gaps = 21/212 (9%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            Q++EG+   +  +V  K +P   +EW  + K L +  R     +    TL L      D 
Sbjct: 1068 QIIEGEDAVMTCEVTGKPEPS--VEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDE 1125

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD 3041
             +YTC A N  G   +S+ +    K  +      P   E +  +   E+ ++ EP     
Sbjct: 1126 ALYTCTASNSLGSVSSSAELQVDEKGVV------PISPEPVSPV--FEEPVKAEP----- 1172

Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV- 3100
             D G          D+V +  G+ A  +A +  TG     +EW  +G+ +E + R   V 
Sbjct: 1173 -DEGTVAPVIEGLNDVV-VPLGREAKLDARI--TGSPKPEVEWIKDGQVVEDAGRFLYVE 1228

Query: 3101 -YAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
                G+  L I   +  D+G Y C A N+ G+
Sbjct: 1229 NEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 61/224 (27%), Positives = 92/224 (41%), Gaps = 42/224 (18%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            V +KP FVT+ K  E  +EG    F+ K++       +VEWF     +    RFR   + 
Sbjct: 857  VPVKPSFVTKLKPTE-AVEGGEARFDVKVKG--SPKPEVEWFSGTTKIAEKGRFR-FEEV 912

Query: 1500 G--YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            G    +L + DL   DSG   C     + T+E   ++T R+  ++              V
Sbjct: 913  GEEQFSLVLTDLQLTDSGTIKC-----IATNEAG-KVTSRADLNVKERLF-------APV 959

Query: 1558 LEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNN 1617
             ED               Q PI     + + IK   +A       P +D    V+W  N 
Sbjct: 960  FEDEE-------------QGPIKVQEGEEISIKSVVKAK------PKAD----VKWMKNG 996

Query: 1618 KPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            KPLK  S+    +      + I +   +DSG YTC A N++G+A
Sbjct: 997  KPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKA 1040



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 5/94 (5%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
           + A +P E +P I E + K+    +G  A  E K  G PTP V W +    + E  +   
Sbjct: 126 VEAEKPSEVAPLITEPL-KSLEVPEGATATLECKATGIPTPTVEWRKDNIRVREGRRIK- 183

Query: 121 RYNEQTGD-VSLLIKQIGPGDEGEYTCTARNQYG 153
               Q GD + ++IK     D+GEY C  +N +G
Sbjct: 184 --TTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFG 215



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 6/101 (5%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V +KP FV + K  E  IEG    F+ +++     +  VEWF+    +T   RF  + +
Sbjct: 226  NVPVKPSFVKKMKPSEG-IEGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFH-VEE 281

Query: 1499 FG--YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
             G    +L IIDL+ ED+G++ C A N  G       LT +
Sbjct: 282  TGEDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVK 322



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 4/119 (3%)

Query: 3416 KGKAPVFTVP--LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            K KAP    P  L  I+ L  GE+   +  LT T +   KVEW  N   +K   R ++  
Sbjct: 757  KFKAPAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKA 816

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA--SMKVQGKRNIILESQLPKGMEG 3530
            D     L I  +  ED G Y C   N+YG   + A  +++V  K + + + +  + +EG
Sbjct: 817  DNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAVEG 875



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 26/88 (29%), Positives = 47/88 (53%), Gaps = 5/88 (5%)

Query: 69  PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
           P  P F +  K +   +GG A+F+ +++G+P P V W R    + +  ++ +   E+TG+
Sbjct: 228 PVKPSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHV---EETGE 284

Query: 129 --VSLLIKQIGPGDEGEYTCTARNQYGE 154
              SL+I  +   D G + C A N+ G+
Sbjct: 285 DQYSLVIIDLVTEDAGVFKCVASNEAGK 312



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 6/96 (6%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            PQ  +PI+  EV E   V L  T T    P  +VEW  N   V++ +R K+  D     L
Sbjct: 766  PQILEPIQPLEVGEDQIVKLTLTFTSEQAP--KVEWLKNNIRVKESYRIKSKADNDTATL 823

Query: 2038 DILYAYAEDTGTYMCKATNAVG----EAVTTSSVKV 2069
             I  + AED G Y C   N  G    EA+ T  V V
Sbjct: 824  TIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPV 859



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 1/92 (1%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK-HEIITTHNHTTLR 324
           P   +K + S+  EG +A+F VQ+ G+P+P V WF+   ++ +  + H   T  +  +L 
Sbjct: 231 PSFVKKMKPSEGIEGGEARFDVQIKGSPKPDVEWFRGMTKITDKERFHVEETGEDQYSLV 290

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
           + +    D+G +  +A N  G I     L V+
Sbjct: 291 IIDLVTEDAGVFKCVASNEAGKITARADLTVK 322



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 3/97 (3%)

Query: 1710 APVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            APVF    +  I+V E +    ++  +    PK  V+W++NG P++ S+++         
Sbjct: 957  APVFEDEEQGPIKVQEGEEISIKS--VVKAKPKADVKWMKNGKPLKDSSKVDVRSRDDTH 1014

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             + +K    +DSG YTC A N +G+A  + ++ V+ K
Sbjct: 1015 NVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVEKK 1051



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 8/153 (5%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG--KVLQSGH-RYR 1894
            V V   P F+T+L  PT+  EG  A ++ +++  P P   VEW F+G  K+ + G  R+ 
Sbjct: 855  VRVPVKPSFVTKLK-PTEAVEGGEARFDVKVKGSPKP--EVEW-FSGTTKIAEKGRFRFE 910

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
               +  F +L +  +   DSG   C A N  G+  S   LNV+ +         E    K
Sbjct: 911  EVGEEQF-SLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIK 969

Query: 1955 IQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNA 1987
            +Q  E+ S            V+  + GKP+K++
Sbjct: 970  VQEGEEISIKSVVKAKPKADVKWMKNGKPLKDS 1002



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 59/257 (22%), Positives = 100/257 (38%), Gaps = 35/257 (13%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVS 2832
            VF   L +I+   G+    +  V    +    ++W+  ++ +    R+    D      S
Sbjct: 18   VFKQPLKDIIAIAGEEAKLDVIVSVGAE----VDWYRGDQAIEDKGRFMLVDDEGEGMFS 73

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEE 2892
            L I      DSG+Y C A N+ G  ++   L       I  D   P             E
Sbjct: 74   LLIDDVQPSDSGMYECVAFNNAGEVSSKAEL-------IVNDGASP-----------VPE 115

Query: 2893 ARLAKGRRPSVPDTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKNDPDLKIEWY 2948
             ++ +   P+V   E  KP  + P+  E     ++ EG    LE   +    P   +EW 
Sbjct: 116  EKIQEETAPAV---EAEKPSEVAPLITEPLKSLEVPEGATATLE--CKATGIPTPTVEWR 170

Query: 2949 FNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS--TVYCTSK 3006
             +   + +G R K T D   + + + D    D G Y C   N  G  +T++  TV    K
Sbjct: 171  KDNIRVREGRRIKTTQDGDTLRIVIKDAIGTDQGEYKCMVKNDFGLDYTTAKLTVNVPVK 230

Query: 3007 DNLIERTQHPKGTEGLE 3023
             + +++ +  +G EG E
Sbjct: 231  PSFVKKMKPSEGIEGGE 247



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            Q APIF         L +G  + ++  +  +  P+  + W+ NG  L +   L       
Sbjct: 325  QFAPIFEDEQMGPVILRKGDELSIKETIRAKPKPD--VNWYHNGKPLRSAPTLDIRSRGD 382

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
              +L+I S + +D+G Y C+A N LG+A+ T  +++E++
Sbjct: 383  THSLAIISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQ 421



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   V WY NG+P++              +L I+ A  ED G Y C+A N +G+A+ T  
Sbjct: 356  PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYD 415

Query: 2067 VKVD--AKSGLYLDTLDEQRLKKIQELE 2092
            V+V+  A  G     L E + +++ E E
Sbjct: 416  VRVEEQAPKGTAPTILSEMKPQQVVEGE 443



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 23/63 (36%), Positives = 34/63 (53%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P   V WY +G+P+ ++  +         SL I+  + EDAG Y   A NKLG+A+ T  
Sbjct: 356 PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYD 415

Query: 860 IRV 862
           +RV
Sbjct: 416 VRV 418



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 21/60 (35%), Positives = 30/60 (50%)

Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            K+EW KN + +    R+KS  D    TL+I   R +D G+Y C   N  G   S A + +
Sbjct: 796  KVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV 855



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 38/158 (24%), Positives = 71/158 (44%), Gaps = 11/158 (6%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V+E E +  +  V+ K  PK  ++W +NGK L    +          ++ I     +DSG
Sbjct: 970  VQEGEEISIKSVVKAK--PKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSG 1027

Query: 3901 EYICRAVNDFGEDFTKATISCKK------LPDIILQNQVPRGMKRSEALTQMEATIKKYT 3954
            EY C A N  G+     ++  +K       P +I + +  + ++  +A+   E T K   
Sbjct: 1028 EYTCEATNSVGKASRTYSVEVEKKVPKGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEP 1087

Query: 3955 SEVYLTEDDLYDVDKKQPPRF---VTQIQSQTSLVEME 3989
            S  +L +D     D++  P +   V  ++ Q +++E E
Sbjct: 1088 SVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDE 1125



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/82 (31%), Positives = 38/82 (46%)

Query: 2377 VFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSM 2436
            V  Q L+ I  ++ G+       L    +   KVEW +N   +++S RI    D    ++
Sbjct: 764  VAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKADNDTATL 823

Query: 2437 TISHVRDEDEGVYMCRASNLLG 2458
            TI   R ED+GVY C   N  G
Sbjct: 824  TIKQSRAEDQGVYQCVIRNDYG 845



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 6/87 (6%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFG 2432
            +P F + ++  + I+ G+ A FD ++   G P   VEWFR    I D  R  + +T +  
Sbjct: 230  KPSFVKKMKPSEGIEGGE-ARFDVQI--KGSPKPDVEWFRGMTKITDKERFHVEETGEDQ 286

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459
            Y S+ I  +  ED GV+ C ASN  G+
Sbjct: 287  Y-SLVIIDLVTEDAGVFKCVASNEAGK 312



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/101 (27%), Positives = 57/101 (56%), Gaps = 10/101 (9%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR---TFHD-F 3337
            P F+ +++  ++ +EG  A F+ ++     PD  VEWF    K+    R+    T  D +
Sbjct: 231  PSFVKKMKP-SEGIEGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEETGEDQY 287

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
             +VI+D++    E++G ++CVA+N+ G+ + +A+L    ++
Sbjct: 288  SLVIIDLV---TEDAGVFKCVASNEAGKITARADLTVKERQ 325



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 2/82 (2%)

Query: 781  ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
            ++QEG     ++ +   + P   V+W K+G+P+  SS++         ++ I   + +D+
Sbjct: 969  KVQEGEEISIKSVVK--AKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDS 1026

Query: 841  GSYTVRAVNKLGEAISTASIRV 862
            G YT  A N +G+A  T S+ V
Sbjct: 1027 GEYTCEATNSVGKASRTYSVEV 1048



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 58/223 (26%), Positives = 89/223 (39%), Gaps = 43/223 (19%)

Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT--LND 3749
            P  P F  ++K +  + EGG   FD +++  G P   ++WF          R H     +
Sbjct: 228  PVKPSFVKKMKPSEGI-EGGEARFDVQIK--GSPKPDVEWFRGMTKITDKERFHVEETGE 284

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809
              +  + ID +   DAG + C A+N+ G      KIT  A+ D+              +K
Sbjct: 285  DQYSLVIIDLV-TEDAGVFKCVASNEAG------KIT--ARADLT-------------VK 322

Query: 3810 ELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
            E +   I +  +  P++          K   +   E +R     +PK D    + WY NG
Sbjct: 323  ERQFAPIFEDEQMGPVILR--------KGDELSIKETIR----AKPKPD----VNWYHNG 366

Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            K L S             SL I+    ED+GEY C A N  G+
Sbjct: 367  KPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGK 409



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 2/79 (2%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            L +G  L ++  +  K  PD  + WY NGK L       + S     +L ++     D+G
Sbjct: 340  LRKGDELSIKETIRAKPKPD--VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAG 397

Query: 2983 IYTCKAYNKRGEAFTSSTV 3001
             Y C+A+NK G+A  +  V
Sbjct: 398  EYRCEAHNKLGKALRTYDV 416



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 21/75 (28%), Positives = 41/75 (54%), Gaps = 2/75 (2%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +   EG +I  ++ ++    P   ++W+KNG+ ++ SS+     R    ++ + +  + D
Sbjct: 968  IKVQEGEEISIKSVVK--AKPKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDD 1025

Query: 706  SGEYTCRAVSATGVA 720
            SGEYTC A ++ G A
Sbjct: 1026 SGEYTCEATNSVGKA 1040



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 51/213 (23%), Positives = 86/213 (40%), Gaps = 22/213 (10%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576
            P ++ EG+ A     V    +PS+  EW  +   L    R    ++    TL +   +  
Sbjct: 1066 PMQIIEGEDAVMTCEVTGKPEPSV--EWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILE 1123

Query: 2577 DAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQ-LKEAAMNKVPEMFVD 2635
            D  LY C A N  G               + ++ + P S E +  + E  +   P    D
Sbjct: 1124 DEALYTCTASNSLGSVSSSAELQ------VDEKGVVPISPEPVSPVFEEPVKAEP----D 1173

Query: 2636 TGVQQAPIFTTHLKSYDKLVE-GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-- 2692
             G   AP+        D +V  G+   L+A++     P  ++EW K+G  +    R    
Sbjct: 1174 EGTV-APVIEG---LNDVVVPLGREAKLDARITGSPKP--EVEWIKDGQVVEDAGRFLYV 1227

Query: 2693 STFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
               + G+ +L I+ ++ +D+G Y C A N  GE
Sbjct: 1228 ENEEPGIFSLVIDDVQPEDAGKYKCIAFNEKGE 1260



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 38/149 (25%), Positives = 61/149 (40%), Gaps = 10/149 (6%)

Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737
            T+H    +T+    P  P F  ++K   +  EGG   FD +V+  G P   ++WF     
Sbjct: 846  TVHSEAMLTVR--VPVKPSFVTKLKPT-EAVEGGEARFDVKVK--GSPKPEVEWFSGTTK 900

Query: 3738 FATGSRVHTLNDFGF--IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795
             A   R     + G    +L +  +   D+G   C ATN+ G  T+ A +    +    +
Sbjct: 901  IAEKGRFR-FEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPV 959

Query: 3796 ESQLPQGMSGEKIKELERGRISDAPKEEP 3824
                 QG    K++E E   I    K +P
Sbjct: 960  FEDEEQGPI--KVQEGEEISIKSVVKAKP 986



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 21/62 (33%), Positives = 34/62 (54%)

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            V+W  NGKP+K   +       D   + + +   +DSG YTC+ATN +G+A  + ++ V 
Sbjct: 990  VKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDDSGEYTCEATNSVGKASRTYSVEVE 1049

Query: 1404 AK 1405
             K
Sbjct: 1050 KK 1051



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 63/238 (26%), Positives = 87/238 (36%), Gaps = 35/238 (14%)

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMG--FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
            ++WYR  + +    R+  V D G    SL I  V   DSG Y C A N+ GE  +KA + 
Sbjct: 46   VDWYRGDQAIEDKGRFMLVDDEGEGMFSLLIDDVQPSDSGMYECVAFNNAGEVSSKAELI 105

Query: 3921 CKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQ 3980
                      + VP    + E    +EA   +  SEV                  +T+  
Sbjct: 106  VNDGA-----SPVPEEKIQEETAPAVEA---EKPSEV---------------APLITEPL 142

Query: 3981 SQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYP 4040
                + E  T   EC+    G P   VEW  +   +    R     D   + +       
Sbjct: 143  KSLEVPEGATATLECKAT--GIPTPTVEWRKDNIRVREGRRIKTTQDGDTLRIVIKDAIG 200

Query: 4041 EDSGEYLCRATNLYGMDET--KAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQV 4096
             D GEY C   N +G+D T  K  +    KP  V      K MK  E I   EA + V
Sbjct: 201  TDQGEYKCMVKNDFGLDYTTAKLTVNVPVKPSFV------KKMKPSEGIEGGEARFDV 252



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           PQ + P+Q L   + G +   +  LT  S+   +VEW K+   +  S RI S  +    +
Sbjct: 766 PQILEPIQPL---EVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKADNDTAT 822

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           L I   RAED G Y     N  G   S A + V
Sbjct: 823 LTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV 855



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 37/148 (25%), Positives = 56/148 (37%), Gaps = 3/148 (2%)

Query: 1282 EQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQT 1341
            +Q + Q  +  D      +    + V   P F   L   E VEG     + +++  G   
Sbjct: 832  DQGVYQCVIRNDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAVEGGEARFDVKVK--GSPK 889

Query: 1342 MRVEWFCNGKPIKTGHRFR-PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
              VEWF     I    RFR      +  +L L  +   DSG   C ATN+ G+  +   L
Sbjct: 890  PEVEWFSGTTKIAEKGRFRFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADL 949

Query: 1401 RVIAKKDLILESQHPSGLEKIQYLEDTS 1428
             V  +    +      G  K+Q  E+ S
Sbjct: 950  NVKERLFAPVFEDEEQGPIKVQEGEEIS 977



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGH-RYRTVYD 3883
            V   P F+T++K     E    RF+ +V  K  PK  +EW+    K+   G  R+  V +
Sbjct: 857  VPVKPSFVTKLKPTEAVEGGEARFDVKV--KGSPKPEVEWFSGTTKIAEKGRFRFEEVGE 914

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
              F SL +  +   DSG   C A N+ G+  ++A ++ K+
Sbjct: 915  EQF-SLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKE 953



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694
           P F+  +K    +EGG+  F+ +I+  G P   +EW +    I    RF  +   G    
Sbjct: 231 PSFVKKMKPSEGIEGGEARFDVQIK--GSPKPDVEWFRGMTKITDKERF-HVEETGEDQY 287

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
           SL ++ L  +D+G + C A +  G    +A L V  R
Sbjct: 288 SLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKER 324



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 24/65 (36%), Positives = 31/65 (47%)

Query: 1071 SDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLS 1130
            S+    VEW  N  ++  + RI++  D     L I   RAED GVY  V RN  G     
Sbjct: 791  SEQAPKVEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSE 850

Query: 1131 ASMTV 1135
            A +TV
Sbjct: 851  AMLTV 855



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 2/81 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            I  +EG+ I  +  V+    P   ++W  N KPL   ++          ++ I     +D
Sbjct: 968  IKVQEGEEISIKSVVKAK--PKADVKWMKNGKPLKDSSKVDVRSRDDTHNVTIKTAKVDD 1025

Query: 2843 SGIYTCKATNSKGSATTSGSL 2863
            SG YTC+ATNS G A+ + S+
Sbjct: 1026 SGEYTCEATNSVGKASRTYSV 1046



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 9/122 (7%)

Query: 2143 IDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
            ++W  N  +++  +R ++  D     L I  + AED G Y C   N  G   +   L V 
Sbjct: 797  VEWLKNNIRVKESYRIKSKADNDTATLTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVR 856

Query: 2203 GHRNIILDTQHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAH 2261
                       P+ + K++  EA +G   R +V + K SP   V    GTT + E     
Sbjct: 857  -------VPVKPSFVTKLKPTEAVEGGEARFDV-KVKGSPKPEVEWFSGTTKIAEKGRFR 908

Query: 2262 FE 2263
            FE
Sbjct: 909  FE 910



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E  +   V   P F T LK  +  VEG     + +V  +  P  ++EWF     +    R
Sbjct: 850  EAMLTVRVPVKPSFVTKLKPTEA-VEGGEARFDVKV--KGSPKPEVEWFSGTTKIAEKGR 906

Query: 2691 LK-STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             +         +L +  L+  DSG   C ATN  G+  S A + +++R
Sbjct: 907  FRFEEVGEEQFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKER 954



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V   P F+ ++K     E    RF+ ++  K  PK  +EW+R    +    R+  V + G
Sbjct: 227  VPVKPSFVKKMKPSEGIEGGEARFDVQI--KGSPKPDVEWFRGMTKITDKERFH-VEETG 283

Query: 3886 --FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
                SL I+ +  ED+G + C A N+ G+   +A ++ K+
Sbjct: 284  EDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKE 323



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 38/142 (26%), Positives = 61/142 (42%), Gaps = 10/142 (7%)

Query: 1006 DIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFE 1064
            D++ E     G+ K     +A + + R +  VK  Q  P F     G   + +G     +
Sbjct: 293  DLVTED---AGVFKCVASNEAGKITARADLTVKERQFAPIFEDEQMGPVILRKGDELSIK 349

Query: 1065 A--RVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
               R +P+ D    V WY NGK + SA  +         +L I S + ED+G Y   A N
Sbjct: 350  ETIRAKPKPD----VNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHN 405

Query: 1123 AAGEAQLSASMTVETRSSIDTS 1144
              G+A  +  + VE ++   T+
Sbjct: 406  KLGKALRTYDVRVEEQAPKGTA 427



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P+F+Q  K+     G  AK +  +       V W R    + +  ++ +  +E  G  SL
Sbjct: 17  PVFKQPLKDIIAIAGEEAKLDVIVSVGAE--VDWYRGDQAIEDKGRFMLVDDEGEGMFSL 74

Query: 132 LIKQIGPGDEGEYTCTARNQYGE 154
           LI  + P D G Y C A N  GE
Sbjct: 75  LIDDVQPSDSGMYECVAFNNAGE 97



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 3/99 (3%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V   P F + +   E +EG     + +++  G     VEWF     I    RF     
Sbjct: 225  VNVPVKPSFVKKMKPSEGIEGGEARFDVQIK--GSPKPDVEWFRGMTKITDKERFHVEET 282

Query: 1365 F-DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
              D  +L ++ +  ED+GV+ C A+N+ G+      L V
Sbjct: 283  GEDQYSLVIIDLVTEDAGVFKCVASNEAGKITARADLTV 321



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 9/133 (6%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI--TFDFGY 2299
            P FV +++ +  + EG  A F+ Q++    P+  +E++     +    RFH+  T +  Y
Sbjct: 231  PSFVKKMKPSEGI-EGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEETGEDQY 287

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQR-PEGLEKIREL 2356
             SL I   V EDAG +   A N  G  T+   +TV  +    I  + Q  P  L K  EL
Sbjct: 288  -SLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKERQFAPIFEDEQMGPVILRKGDEL 346

Query: 2357 ESAEPFKRPEIPE 2369
               E  +    P+
Sbjct: 347  SIKETIRAKPKPD 359



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 12/116 (10%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR--- 1894
            V V   P F+ ++  P++  EG  A ++ +I+  P P+  VEW+     +    R+    
Sbjct: 225  VNVPVKPSFVKKMK-PSEGIEGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEE 281

Query: 1895 TSND-FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE--SIIRDSQ 1947
            T  D +    +D++T   ED+G + C A N  G+  +   L V+ ++   I  D Q
Sbjct: 282  TGEDQYSLVIIDLVT---EDAGVFKCVASNEAGKITARADLTVKERQFAPIFEDEQ 334



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 3/97 (3%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           P   +P I  ++ K  +  +G +      + G P P V W ++  PL   +    +Y  +
Sbjct: 423 PKGTAPTILSEM-KPQQVVEGEDVMLACAVSGKPEPTVEWLKEGKPLSRDSHVRPKYEAE 481

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
               +L  K     DE  YTC A N  G    S  +Q
Sbjct: 482 IA--TLTFKSATLEDEALYTCVATNALGSVSSSAELQ 516



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 5/112 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P  ++P+    P+  G++  ++  L    +   +VEW  N   V    R K+  D     
Sbjct: 766  PQILEPIQ---PLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKADNDTAT 822

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAI--VRVIERSDIVTDTQNEQAIE 1286
            L I  + + D G Y     N  G+ H+ A+  VRV  +   VT  +  +A+E
Sbjct: 823  LTIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTVRVPVKPSFVTKLKPTEAVE 874



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 13/123 (10%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY----DF 2032
            KP F   +K  E  EG     +  +     P   VEW+     + +  RF+        F
Sbjct: 860  KPSFVTKLKPTEAVEGGEARFDVKVK--GSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQF 917

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL--DEQRLKKIQE 2090
              V  D+      D+GT  C ATN  G+   TS   ++ K  L+      +EQ   K+QE
Sbjct: 918  SLVLTDLQLT---DSGTIKCIATNEAGK--VTSRADLNVKERLFAPVFEDEEQGPIKVQE 972

Query: 2091 LEK 2093
             E+
Sbjct: 973  GEE 975



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 2/97 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P+F      P  + +G  + ++  +     P   V W+HNG+ +               +
Sbjct: 328  PIFEDEQMGPVILRKGDELSIKETIRAKPKPD--VNWYHNGKPLRSAPTLDIRSRGDTHS 385

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273
            L II A   D GEY   A N LG A  +  VRV E++
Sbjct: 386  LAIISAKLEDAGEYRCEAHNKLGKALRTYDVRVEEQA 422



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 21/67 (31%), Positives = 34/67 (50%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799
            PK  V W  NG P+ ++  L         +L +     ED+G Y C A N+LG+A+ +  
Sbjct: 356  PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKALRTYD 415

Query: 1800 LFVQSKA 1806
            + V+ +A
Sbjct: 416  VRVEEQA 422



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 24/100 (24%), Positives = 50/100 (50%), Gaps = 6/100 (6%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFGL 2699
            P F   +K  +  +EG     + Q++    P+  +EWF+    +T   R  ++ T +   
Sbjct: 231  PSFVKKMKPSEG-IEGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEETGE-DQ 286

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHW 2739
             +L I  L  +D+G++ C A+N  G+  + A + +++R +
Sbjct: 287  YSLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKERQF 326



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 5/97 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   MK     E   A F+ ++   G PK  VEW R    I    R   + + G    
Sbjct: 231  PSFVKKMKPSEGIEGGEARFDVQI--KGSPKPDVEWFRGMTKITDKERFH-VEETGEDQY 287

Query: 1771 NMKYVN--PEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            ++  ++   ED+G + C A NE G+    + L V+ +
Sbjct: 288  SLVIIDLVTEDAGVFKCVASNEAGKITARADLTVKER 324



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 9/92 (9%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK----STHDFSYV 2831
            F++ L      EG    F+  V+ S  P  ++EWF     +    R++        FS V
Sbjct: 863  FVTKLKPTEAVEGGEARFDVKVKGSPKP--EVEWFSGTTKIAEKGRFRFEEVGEEQFSLV 920

Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
              D+  T   DSG   C ATN  G  T+   L
Sbjct: 921  LTDLQLT---DSGTIKCIATNEAGKVTSRADL 949



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 10/88 (11%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR---TTHD- 2562
            KP F + +  PSE  EG  A ++ ++   G P    EW+    ++    RF    T  D 
Sbjct: 230  KPSFVKKMK-PSEGIEGGEARFDVQIK--GSPKPDVEWFRGMTKITDKERFHVEETGEDQ 286

Query: 2563 FGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +  V +D+   V  DAG++ C A N AG
Sbjct: 287  YSLVIIDL---VTEDAGVFKCVASNEAG 311



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 19/63 (30%), Positives = 28/63 (44%)

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            +V E++     P  +S      V EGE     C V+G P+P V WL  G  +   S  + 
Sbjct: 417  RVEEQAPKGTAPTILSEMKPQQVVEGEDVMLACAVSGKPEPTVEWLKEGKPLSRDSHVRP 476

Query: 4160 TYD 4162
             Y+
Sbjct: 477  KYE 479



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 5/79 (6%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVSLDITHTYEEDSG 2844
            EG    F+  ++ S  P   +EWF     +    R+  + T +  Y SL I     ED+G
Sbjct: 244  EGGEARFDVQIKGSPKPD--VEWFRGMTKITDKERFHVEETGEDQY-SLVIIDLVTEDAG 300

Query: 2845 IYTCKATNSKGSATTSGSL 2863
            ++ C A+N  G  T    L
Sbjct: 301  VFKCVASNEAGKITARADL 319



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 6/120 (5%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG-- 2432
            +P F   L+  + ++ G+ A FD ++   G P  +VEWF     I +  R  +  + G  
Sbjct: 860  KPSFVTKLKPTEAVEGGE-ARFDVKV--KGSPKPEVEWFSGTTKIAEKGRF-RFEEVGEE 915

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQ 2492
              S+ ++ ++  D G   C A+N  G+                +     +G  K+Q+ E+
Sbjct: 916  QFSLVLTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGEE 975



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 3/89 (3%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            +R+F  PIF     GP  L +G     +  +     P +   WY NG  L+         
Sbjct: 323  ERQFA-PIFEDEQMGPVILRKGDELSIKETIRAKPKPDVN--WYHNGKPLRSAPTLDIRS 379

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                 +L I S    DAG Y C+A N+ G
Sbjct: 380  RGDTHSLAIISAKLEDAGEYRCEAHNKLG 408



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 16/55 (29%), Positives = 27/55 (49%)

Query: 666 PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           P   + W  NG+ + ++       R    SL ++S  ++D+GEY C A +  G A
Sbjct: 356 PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGKA 410



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 19/54 (35%), Positives = 25/54 (46%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGR 3365
            P   V W++NGK L                L I+    E++GEY C A NKLG+
Sbjct: 356  PKPDVNWYHNGKPLRSAPTLDIRSRGDTHSLAIISAKLEDAGEYRCEAHNKLGK 409



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 2/89 (2%)

Query: 2504 EFEKP--IFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            +F+ P  +  Q+L     L  G+    +  +    + + + EW  N + +K   R ++  
Sbjct: 757  KFKAPAGVAPQILEPIQPLEVGEDQIVKLTLTFTSEQAPKVEWLKNNIRVKESYRIKSKA 816

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            D    TL I    A D G+Y C   N  G
Sbjct: 817  DNDTATLTIKQSRAEDQGVYQCVIRNDYG 845



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           PQ + P++ +   E   +           P  K+EWLKN   ++ S R  S       +L
Sbjct: 766 PQILEPIQPLEVGEDQIVKLTLTFTSEQAP--KVEWLKNNIRVKESYRIKSKADNDTATL 823

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +     +D G Y C   +  G   ++A+L V
Sbjct: 824 TIKQSRAEDQGVYQCVIRNDYGTVHSEAMLTV 855



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 8/88 (9%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNG--KVLEQGS-RFKLTSDF 2966
            KP ++  +    + VEG     +  V+ K  P  ++EW F+G  K+ E+G  RF+   + 
Sbjct: 860  KPSFVTKLKPT-EAVEGGEARFD--VKVKGSPKPEVEW-FSGTTKIAEKGRFRFEEVGEE 915

Query: 2967 GFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
             F +L L D+   DSG   C A N+ G+
Sbjct: 916  QF-SLVLTDLQLTDSGTIKCIATNEAGK 942



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 11/124 (8%)

Query: 3591 VEWFHNGKPLLTGSRV---KTIND-FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
            VEWF     +    R    +T  D +  VI+++      DAG++ C A+N  G+ T    
Sbjct: 262  VEWFRGMTKITDKERFHVEETGEDQYSLVIIDL---VTEDAGVFKCVASNEAGKITARAD 318

Query: 3647 LQVKGRQ--GIILEPQL-PSHFKSGTE-SIQKLEETLHKREEITIEDEKPNPPRFTVEIK 3702
            L VK RQ   I  + Q+ P   + G E SI++      K +     + KP     T++I+
Sbjct: 319  LTVKERQFAPIFEDEQMGPVILRKGDELSIKETIRAKPKPDVNWYHNGKPLRSAPTLDIR 378

Query: 3703 DNID 3706
               D
Sbjct: 379  SRGD 382



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 9/155 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK--TINDFGFV 3615
            P F T        E   A F+ ++         VEWF     +    R +   + +  F 
Sbjct: 861  PSFVTKLKPTEAVEGGEARFDVKV--KGSPKPEVEWFSGTTKIAEKGRFRFEEVGEEQFS 918

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL---EPQLPSHFKSGTE-S 3671
            ++ +  +   D+G   C ATN  G+ T    L VK R    +   E Q P   + G E S
Sbjct: 919  LV-LTDLQLTDSGTIKCIATNEAGKVTSRADLNVKERLFAPVFEDEEQGPIKVQEGEEIS 977

Query: 3672 IQKLEETLHKREEITIEDEKPNPPRFTVEIKDNID 3706
            I+ + +   K +   +++ KP      V+++   D
Sbjct: 978  IKSVVKAKPKADVKWMKNGKPLKDSSKVDVRSRDD 1012


>SB_29786| Best HMM Match : I-set (HMM E-Value=0)
          Length = 6300

 Score =  202 bits (493), Expect = 6e-51
 Identities = 117/404 (28%), Positives = 189/404 (46%), Gaps = 21/404 (5%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP F  K    ++ E + A+FE    G P P ++W R+  PIK    FQI     +S+L
Sbjct: 3058 RPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVL 3117

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I    + D   +  VA ++ G   CS  L+V+E        +VPP F     N+ +T G
Sbjct: 3118 TIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDE-------AVVPPEFVRKISNIELTEG 3170

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            ++ R D ++TGT   +V W K+   ++   R +I  +D  ++L+I +    D+G Y C A
Sbjct: 3171 EIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKA 3230

Query: 4589 INSAGEARCDAECVVS-LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
             N AG+A C  E  ++ +P     P   T+ A   P   E        EG  I F   + 
Sbjct: 3231 TNEAGQASCYGELTITFIPV----PPHFTEEAPKIPTDFE--------EGGDITFEATVS 3278

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G+P P V+W+K +  I  S ++ + R+ D Y+L I    P+D G Y C A N  G     
Sbjct: 3279 GRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRT 3338

Query: 4708 AKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
              + +   +   + P    L + + V EGQ A F+  +    +P+I+W + G  + E   
Sbjct: 3339 YNIDIEASEPKGSTPQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENER 3398

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                +EG  + L I     +D G + C A  + G+   + +L+V
Sbjct: 3399 IASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442



 Score =  183 bits (446), Expect = 3e-45
 Identities = 118/409 (28%), Positives = 182/409 (44%), Gaps = 25/409 (6%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPD--FQIHTFSTKSI 4467
            PP F   ++   V E       +   G P P + W+++  P+   P   F++        
Sbjct: 2199 PPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYT 2258

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L+I++    D+  +   A N  G    S N+ V     +      PP F    +++ +  
Sbjct: 2259 LVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKE-----PPKFERNLKDITIAE 2313

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G   R D +VTG+    V+W  NGK VQP     I+ +D   +L+++      SGKY CV
Sbjct: 2314 GCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCV 2373

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N  G+ +  A   ++  A +             P+  E L +  ++ G  I   C++ 
Sbjct: 2374 AENEVGQVQSAARLHITELAIQ-------------PKFAERLTNVSISSGDTIVLECRVT 2420

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQM-SRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            GKP P V W+K DK I+    F   +R  D   L I    P+DEG YKC+A N AG+   
Sbjct: 2421 GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDT 2480

Query: 4707 AAKLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             A+L V +     N P     L DI V EG   +F+  +    KP I W +   LI   P
Sbjct: 2481 VAELTVAK---RGNPPFFVKELVDIDVTEGGHERFEVVVDGYPKPEIDWYKNDILIRPGP 2537

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             F +   G++  L++ +   E+TG  TC+A  +AGQ   S  + +  KT
Sbjct: 2538 KFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKT 2586



 Score =  183 bits (445), Expect = 4e-45
 Identities = 103/402 (25%), Positives = 189/402 (47%), Gaps = 20/402 (4%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F ++++   V E  +   EVE  G+P P+++W ++   +K S    + T      L I
Sbjct: 2964 PKFLQRLELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTI 3023

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                ++D   +  +A+N+ G   C+A L+VEE       G+ PP F +   ++ +  G++
Sbjct: 3024 MNTTLDDEGEYTCIAKNKVGEVSCTAELLVEE-------GMRPPQFIVKPSSLQIMEGKM 3076

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
             + + +V+G    +V WL++G+ ++P  R +I  E     L I++A   D G+Y CVA +
Sbjct: 3077 AKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATS 3136

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
             AG+  C  E +V               A  PPE +  + +  + EG+   F  +I G P
Sbjct: 3137 KAGKDSCSVELLVD-------------EAVVPPEFVRKISNIELTEGEIARFDVRITGTP 3183

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P V WYK +  I+    F++    D+++L I +    D G Y C A N AG+ +   +L
Sbjct: 3184 APEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGEL 3243

Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMI 4770
             +T      +     P       EG    F+  ++ + +P ++W ++ A I E+  + + 
Sbjct: 3244 TITFIPVPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHYHLH 3303

Query: 4771 HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
               +   L I     +D+G +TC AT   G  + +  + +++
Sbjct: 3304 RSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRTYNIDIEA 3345



 Score =  162 bits (393), Expect = 7e-39
 Identities = 114/411 (27%), Positives = 183/411 (44%), Gaps = 29/411 (7%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V P +PP F + ++   + E    RF+V+  G P P + WY     ++      I     
Sbjct: 2294 VAPKEPPKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDE 2353

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
             S LI+    ++ S  +  VAEN  G  + +A L + E   Q       P F     NV+
Sbjct: 2354 HSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHITELAIQ-------PKFAERLTNVS 2406

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY-PQDSGK 4583
            ++SG  + L+ +VTG     V W K+ K+++ D R       G   +L +    P D G 
Sbjct: 2407 ISSGDTIVLECRVTGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGS 2466

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y+C+A N AG+    AE  V+            K  N PP  ++ L D  V EG    F 
Sbjct: 2467 YKCIATNPAGQDDTVAELTVA------------KRGN-PPFFVKELVDIDVTEGGHERFE 2513

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
              + G P P + WYK D LI+P   F +    D +TL + +  PE+ G   C A NSAG+
Sbjct: 2514 VVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQ 2573

Query: 4704 VTVAAKLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI- 4761
               +  +++ +       P +T  L D+ +  G+      +     +P ++W  +   I 
Sbjct: 2574 AICSCFVQINEKTIP---PKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEIT 2630

Query: 4762 -PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              +  D +  H  ++ VL+  +T   DTG + C     AG+  T++K+ VK
Sbjct: 2631 NEDGVDIETSHCTSSLVLVGVDT--PDTGVYRCLVFNPAGEDSTNSKITVK 2679



 Score =  161 bits (390), Expect = 2e-38
 Identities = 156/619 (25%), Positives = 264/619 (42%), Gaps = 48/619 (7%)

Query: 4128 ARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTGKIEVIXXX 4186
            A F   +TG P+P+V WL N   I +G R++   DG +Y   +  +R  D G+I+     
Sbjct: 2854 AIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATN 2913

Query: 4187 XXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQ-RTETELEKTFEER----QVL 4241
                      L V  +  +   +     +P   E  + Q +   E E T E      Q L
Sbjct: 2914 SAGTVTSMASLIVRDKPSEQTELYI---KPVGQEPVEMQFQVPFETEPTDEAGPKFLQRL 2970

Query: 4242 QRQGVID-HRPELKPKVIKEPE--TEWQQSVKRKKNEEYYNKLQELE-NEQVIKESRLRE 4297
            + + V++  R +L+ +V  +P+   EW +  +  K         E + +   I  + L +
Sbjct: 2971 ELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDD 3030

Query: 4298 STHQYAIPGDKV--TSNT----VAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPS 4351
                  I  +KV   S T    V + M          + ++ E ++ K   +   +P P 
Sbjct: 3031 EGEYTCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPE 3090

Query: 4352 ESTVH-GKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEH------KAQTQERVVEGP 4404
               +  G+ +   ++ Q + E   D+ +   I +    E E+      KA      VE  
Sbjct: 3091 VEWLRDGRPIKPGRRFQIEFEK--DRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELL 3148

Query: 4405 VKPSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
            V  +  PP F +K+    + E E ARF+V   G P P + WY++  PI++   F+I++  
Sbjct: 3149 VDEAVVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDD 3208

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523
             K  L+IR   + D+  ++  A N  G A C   L +           VPP FT  A  +
Sbjct: 3209 DKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTITFIP-------VPPHFTEEAPKI 3261

Query: 4524 --NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
              +   G  +  +  V+G    DV W K+   +       +   + TY+L I    P DS
Sbjct: 3262 PTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDS 3321

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G Y C A N  G A+       ++     +PK  T      P+ I+ ++   V EGQ   
Sbjct: 3322 GAYTCTATNECGMAKR----TYNIDIEASEPKGST------PQFIDLMQPVEVTEGQTAT 3371

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            F C + G P P+++W+K    +K ++    +      +L I++   +DEG+YKCVA NS 
Sbjct: 3372 FECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSF 3431

Query: 4702 GRVTVAAKLKVTQPDQADN 4720
            G+ + A +L V + D  ++
Sbjct: 3432 GKASCATELLVDEADSPED 3450



 Score =  158 bits (384), Expect = 9e-38
 Identities = 115/410 (28%), Positives = 191/410 (46%), Gaps = 43/410 (10%)

Query: 4427 QARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAE 4486
            +A FEVE  G+P P ++W + +  I++   F+  +  T   L +R   ++D       A 
Sbjct: 2853 KAIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTAT 2912

Query: 4487 NRGGTAKCSANLVVEEKRRQ---------GRGGI-----VP----------PSFTLTAQN 4522
            N  GT    A+L+V +K  +         G+  +     VP          P F    + 
Sbjct: 2913 NSAGTVTSMASLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRLEL 2972

Query: 4523 VNVTSGQLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
              V  G    L+ +V+G  KP+ V WLK+G+ V+P     +  E   +TL I+     D 
Sbjct: 2973 KEVVEGSRTDLEVEVSGKPKPV-VEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDE 3031

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G+Y C+A N  GE  C AE +V             +    PP+ I       + EG+  +
Sbjct: 3032 GEYTCIAKNKVGEVSCTAELLV-------------EEGMRPPQFIVKPSSLQIMEGKMAK 3078

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            F  ++ G P P V+W +  + IKP + FQ+    D   L I +A   DEG+Y CVA + A
Sbjct: 3079 FEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKA 3138

Query: 4702 GRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
            G+ + + +L V   D+A   P  +  + +I + EG+ A+F  +IT    P + W ++   
Sbjct: 3139 GKDSCSVELLV---DEAVVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVP 3195

Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            I +   F++  + +   L+I +    DTG+++C+AT  AGQ     +L +
Sbjct: 3196 IEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTI 3245



 Score =  146 bits (354), Expect = 4e-34
 Identities = 90/302 (29%), Positives = 144/302 (47%), Gaps = 14/302 (4%)

Query: 283  AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            A F+V+++G P P+V W KN   + + ++ E  +     TL +R ++  D G     A N
Sbjct: 2854 AIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATN 2913

Query: 343  PNGCIVTSGYLAV-ESPTESYVQDQRSQYITDTQQRETEERIEISEKA-----LAPQFVK 396
              G + +   L V + P+E     Q   YI    Q   E + ++  +        P+F++
Sbjct: 2914 SAGTVTSMASLIVRDKPSE-----QTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQ 2968

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
              + ++V EG  T  +  V+G+P P V W + D ++    +   L  E   H L I N T
Sbjct: 2969 RLELKEVVEGSRTDLEVEVSGKPKPVVEW-LKDGELVKPSSLMTLETEGQVHTLTIMNTT 3027

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            L D G  TC+A+NK GE +  C   ++ +E +  P+F+ + S+L + EG+     AR  G
Sbjct: 3028 LDDEGEYTCIAKNKVGEVS--CTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSG 3085

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
             P P + W +DG PI P    +I  +   S L I  AK +D   Y C A + AG  +   
Sbjct: 3086 LPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSV 3145

Query: 577  RL 578
             L
Sbjct: 3146 EL 3147



 Score =  143 bits (346), Expect = 4e-33
 Identities = 98/306 (32%), Positives = 143/306 (46%), Gaps = 18/306 (5%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ--PDIRNKILEEDGTY 4569
            +PP F    +++ V  G  V L   VTG+   +V W K+GK V   P  R ++      Y
Sbjct: 2198 IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            TL+I EA   D+GKY C A NSAGE        V   A K+           PP+    L
Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKE-----------PPKFERNL 2306

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
            KD  +AEG +  F  ++ G P P V WY   KL++P  +  +    DE++  I    P D
Sbjct: 2307 KDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHD-DEHSSLILMHCPLD 2365

Query: 4690 -EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
              G Y CVA N  G+V  AA+L +T  + A        L ++ +  G     + ++T K 
Sbjct: 2366 LSGKYTCVAENEVGQVQSAARLHIT--ELAIQPKFAERLTNVSISSGDTIVLECRVTGKP 2423

Query: 4749 KPTIQWLREGALIPETPDFQM-IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            +P + W ++   I +   F      G+  VL I     +D G++ C AT  AGQ +T A+
Sbjct: 2424 RPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAE 2483

Query: 4808 LVVKSK 4813
            L V  +
Sbjct: 2484 LTVAKR 2489



 Score =  134 bits (324), Expect = 2e-30
 Identities = 128/526 (24%), Positives = 208/526 (39%), Gaps = 49/526 (9%)

Query: 62   TAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR 121
            TA  P +P PP F+   ++    +G        + G+P P V W +   P+         
Sbjct: 2191 TAALP-KPIPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFE 2249

Query: 122  YNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR 180
                 G+V +L+IK+    D G+Y C A N  GE   S  +                  R
Sbjct: 2250 VG-CVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVD----VLHVAPKEPPKFER 2304

Query: 181  HVSETVEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKV---DTFEYRLLREVSF 236
            ++ +    +   T+           KV  Y NG      D   +   D     +L     
Sbjct: 2305 NLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPL 2364

Query: 237  RESITKRYVGESDV-QISTEIDRSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPR 294
              S     V E++V Q+ +     +  ++  PK A++  N  +  G     + +++G PR
Sbjct: 2365 DLSGKYTCVAENEVGQVQSAARLHITELAIQPKFAERLTNVSISSGDTIVLECRVTGKPR 2424

Query: 295  PRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
            P+V WFK+ + +   ++    T       L +R     D        E    CI T+   
Sbjct: 2425 PQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDD--------EGSYKCIATN--- 2473

Query: 354  AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
                                  Q +T   + ++++   P FVK   D DVTEG   RF+ 
Sbjct: 2474 -------------------PAGQDDTVAELTVAKRGNPPFFVKELVDIDVTEGGHERFEV 2514

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH-ALMITNVTLSDSGVVTCVARNKSG 472
             V G P PE+ W+ ND  IR     K  + E G+H  L++ +    ++G +TC ARN +G
Sbjct: 2515 VVDGYPKPEIDWYKNDILIRP--GPKFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAG 2572

Query: 473  ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
            +    C + + EK   + PK  +R   L++  G+ V L  +  GTP P + W  D   I 
Sbjct: 2573 QAICSCFVQINEK--TIPPKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEIT 2630

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
                + I T    S+L +      D   Y+C   N AG  +T +++
Sbjct: 2631 NEDGVDIETSHCTSSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKI 2676



 Score =  124 bits (300), Expect = 1e-27
 Identities = 68/194 (35%), Positives = 96/194 (49%), Gaps = 3/194 (1%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            + E    PQF+       + EGKM +F+ RV+G P PEV W  + R I+     +I   E
Sbjct: 3053 VEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEF-E 3111

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
                 L I +  L+D G  TCVA +K+G+ +  C + ++  E VV P+FV + S + + E
Sbjct: 3112 KDRSVLTIIDAKLNDEGEYTCVATSKAGKDS--CSVELLVDEAVVPPEFVRKISNIELTE 3169

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            GE    + R  GTP P +TW KD VPI       I++D    +L I     SD   Y C 
Sbjct: 3170 GEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCK 3229

Query: 565  AQNVAGSTATRARL 578
            A N AG  +    L
Sbjct: 3230 ATNEAGQASCYGEL 3243



 Score =  121 bits (292), Expect = 1e-26
 Identities = 93/333 (27%), Positives = 153/333 (45%), Gaps = 38/333 (11%)

Query: 240  ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
            I K  VGE  V  + E+    G + PP+   KP + ++ EG  A+F+ ++SG P P V W
Sbjct: 3037 IAKNKVGE--VSCTAELLVEEG-MRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEW 3093

Query: 300  FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
             ++G+ +    + +I    + + L + + + +D G YT +A +  G    S  L V+   
Sbjct: 3094 LRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVD--- 3150

Query: 360  ESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRP 419
            E+ V  +  + I++         IE++E                  G++ RFD R+TG P
Sbjct: 3151 EAVVPPEFVRKISN---------IELTE------------------GEIARFDVRITGTP 3183

Query: 420  YPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCR 479
             PEVTW+ ++  I D    +I  ++   H+L+I +  LSD+G  +C A N++G+ +    
Sbjct: 3184 APEVTWYKDEVPIEDGGRFEI-YSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGE 3242

Query: 480  LNVIEKEQVVAPKFVERFSTL--NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
            L +      V P F E    +  +  EG  +   A   G P P + W KD  PI  +   
Sbjct: 3243 LTITFIP--VPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHY 3300

Query: 538  RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +H      +L I      D+  Y CTA N  G
Sbjct: 3301 HLHRSNDTYSLTIRGVGPDDSGAYTCTATNECG 3333



 Score =  115 bits (277), Expect = 8e-25
 Identities = 107/405 (26%), Positives = 175/405 (43%), Gaps = 40/405 (9%)

Query: 4419 PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVE 4476
            P  + E    + +V   G P P I W+++   +  SPD  I   S   +  ++IRQ  ++
Sbjct: 3975 PFEITEEGDVKLQVRICGIPFPEIDWFKDGRHL--SPDDHIKITSDDDLYTVLIRQPTIK 4032

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKR--RQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            D+  +  + +N  G A  + ++ +E  +  R  RG +          +V   S   V  D
Sbjct: 4033 DTGKYKCIIKNIAGKATRTFDVDIEAVKPSRHVRGELSEHLILPKFIDVTEVSPYRVSYD 4092

Query: 4535 TKVTGTKPI----DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
               T T  +    DV W+K+G+ ++   R  I ++D  + L IL A   D G Y+CV  N
Sbjct: 4093 GDFTLTVKLSGSGDVQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTN 4152

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP--LKDKIVA----EGQAIEFSC 4644
             AG    D     S     +  +P T A   P E++ P  L+D + A    +   ++ + 
Sbjct: 4153 KAG---FDTR---SFDIGLEDLRPHTFAYE-PSELVAPYYLEDGVTAFQMTDAGDVKLTV 4205

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            ++ GKP PTV+W K D+ + PS +F +    D ++L I +    D+G YK +A N  G  
Sbjct: 4206 RVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGGIN 4265

Query: 4705 TVAAKLKV-----TQPDQADNLPALTPLRD-IVVYE---GQPAQFKTQITSKIKPTIQWL 4755
            T    + +     T     D+  A   L D I  YE   G   +   ++T +  PT+ W 
Sbjct: 4266 TKRFNVDIEWDETTTTRVVDDREAPRFLDDGISSYEFTSGGDVKLTVKVTGRPYPTVTWS 4325

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            R+   I     F M  +  N          E+ G++ C     AG
Sbjct: 4326 RDDKDIKPDDTFHMFSDDENPA--------ENQGSYKCTIANEAG 4362



 Score =  113 bits (273), Expect = 2e-24
 Identities = 165/729 (22%), Positives = 276/729 (37%), Gaps = 72/729 (9%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P F+ L   V V EG+ A F C V G+P+P + W  NG  +    R   TY+G +    I
Sbjct: 3353 PQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTI 3412

Query: 4170 PKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTET 4229
             +    D G  + +             L V             A  P    + +    + 
Sbjct: 3413 NQCTIDDEGNYKCVARNSFGKASCATELLV-----------DEADSPEDQVSGKIMNFDR 3461

Query: 4230 ELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQV 4289
            EL++ FE   +          P+++ +V   PE   Q+ +  +  E+   + ++  N   
Sbjct: 3462 ELKRDFEAEDLFN--------PKVQVEVQMPPEG--QREITLESTEQTKPEGKQKWNPHP 3511

Query: 4290 IKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPR-IP 4348
              E   R    Q +   DK   N      A +   N  +TE        +KV Q P+  P
Sbjct: 3512 PAEGPQRNPYRQES--EDKPKWNPHPPVEASKSNPNPQETEFKRNPHPPQKVLQNPKGNP 3569

Query: 4349 DPSESTV------HGKEVHVAKQKQTQK----EVVGDKEITRKITSTETTEIEHKAQTQE 4398
             P E+ +      H  E    K K+       EVV D +      +T  T ++       
Sbjct: 3570 YPHEAEIKPKWNPHPPEEMPDKAKRDSSSIPIEVVRDSDEVSFTMNTRGTGVQIIDSGTM 3629

Query: 4399 RVVEGPV---KPSKPPIFTKKMQ--PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
            R     V      +P    K  +  P  V E    R EV   G P P ++W +++  I +
Sbjct: 3630 RFDTDSVLDDDDERPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIIS 3689

Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513
            SP F + + +    L+I     +D   +  +A N  G A  + ++ VE    + R   V 
Sbjct: 3690 SPHFMVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNVEGANDEMRASFVD 3749

Query: 4514 PSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
                     +++T  G LV L+ K+ G    DV W K+   +    R KI  E     + 
Sbjct: 3750 ME---DRGPLSITEDGDLV-LEVKIKGEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVT 3805

Query: 4573 ILEAYPQDSGKYECVAINSAGEA----RCDAECVV-SLPATKDKPKPQTKAANAPPEIIE 4627
            I +A  +DS        N  G A      D E V+  L     + +   +  N   E + 
Sbjct: 3806 IKDANKEDSVFTNIT--NDFGTAIRRFSIDVESVMPKLQGFVKRDEDFPQFVNV--EGVS 3861

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
            P   ++ +EG  I+   ++ G P P V W+K    + P+++       D + L I    P
Sbjct: 3862 PF--EVTSEGD-IKLQTRVTGFPEPDVSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTP 3918

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL---TPLRDIVVYEGQPAQFKTQI 4744
               G YKCVA N  G  +   ++ +   + A+++        +R   + +G  A    +I
Sbjct: 3919 LYAGTYKCVATNRRGTNSRDFEVTIETGEAAEHITFQQDEETVRAQFIEKGPYAPVPFEI 3978

Query: 4745 TSK--IK----------PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
            T +  +K          P I W ++G  +      ++  + +   +LI     +DTG + 
Sbjct: 3979 TEEGDVKLQVRICGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYK 4038

Query: 4793 CRATTAAGQ 4801
            C     AG+
Sbjct: 4039 CIIKNIAGK 4047



 Score =  107 bits (258), Expect = 2e-22
 Identities = 92/404 (22%), Positives = 162/404 (40%), Gaps = 20/404 (4%)

Query: 4417 MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE 4476
            + P  V      + +    G P P + W+++  P+  +     H      ILII+     
Sbjct: 3860 VSPFEVTSEGDIKLQTRVTGFPEPDVSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPL 3919

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN----------VT 4526
             +  +  VA NR GT      + +E               T+ AQ +           +T
Sbjct: 3920 YAGTYKCVATNRRGTNSRDFEVTIETGEAAEHITFQQDEETVRAQFIEKGPYAPVPFEIT 3979

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
                V+L  ++ G    ++ W K+G+ + PD   KI  +D  YT+LI +   +D+GKY+C
Sbjct: 3980 EEGDVKLQVRICGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKC 4039

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            +  N AG+A    +  +         + +       P+ I+  +          +F+  +
Sbjct: 4040 IIKNIAGKATRTFDVDIEAVKPSRHVRGELSEHLILPKFIDVTEVSPYRVSYDGDFTLTV 4099

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
                   VQW K  ++I+ SK + + +  D + L I  A  +D G YKCV  N AG  T 
Sbjct: 4100 KLSGSGDVQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAGFDTR 4159

Query: 4707 AAKLKV------TQPDQADNLPALTPLRDIV----VYEGQPAQFKTQITSKIKPTIQWLR 4756
            +  + +      T   +   L A   L D V    + +    +   ++  K KPT++W +
Sbjct: 4160 SFDIGLEDLRPHTFAYEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRVRGKPKPTVKWTK 4219

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
                +  +  F ++ E +   LLI    + D G +   AT   G
Sbjct: 4220 NDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGG 4263



 Score =  107 bits (257), Expect = 2e-22
 Identities = 95/365 (26%), Positives = 168/365 (46%), Gaps = 23/365 (6%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            +VE    P+ K+EW  N  ++E G RF+  SD    TL L      D G   C A N  G
Sbjct: 2857 EVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAG 2916

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTV 3053
               + +++    K +  E+T+      G E ++ ++  +  E   +P D+ G  P+F   
Sbjct: 2917 TVTSMASLIVRDKPS--EQTELYIKPVGQEPVE-MQFQVPFE--TEPTDEAG--PKFLQR 2969

Query: 3054 FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV-VLEILG 3112
              ++ ++ EG     E  +  +G    V+EW  +G+ ++ S  + T+   G V  L I+ 
Sbjct: 2970 L-ELKEVVEGSRTDLEVEV--SGKPKPVVEWLKDGELVKPS-SLMTLETEGQVHTLTIMN 3025

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172
            T   D G Y+C A NK G  E+S   E + +   + P+F     +++ + +G+ A FE  
Sbjct: 3026 TTLDDEGEYTCIAKNKVG--EVSCTAELLVEEGMRPPQFIVKPSSLQ-IMEGKMAKFEAR 3082

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            V  +  P+  +EW  +G+P++   R +   +    VL I   + +D GEY C A +K G+
Sbjct: 3083 VSGLPGPE--VEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGK 3140

Query: 3233 DFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVT 3292
            D      +C  +  V    + P+ + KI  +E  +G   +     +  P   +T  +D  
Sbjct: 3141 D------SCSVELLVDEAVVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEV 3194

Query: 3293 KLVEG 3297
             + +G
Sbjct: 3195 PIEDG 3199



 Score =  101 bits (243), Expect = 1e-20
 Identities = 104/423 (24%), Positives = 166/423 (39%), Gaps = 42/423 (9%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F     + +  +G  AKFE ++ G P P V W R   P+    ++ + + +    ++
Sbjct: 3059 PPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLT 3118

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSV-YIQPEGXXXXXXXXXXXXXYRHVSETVEHK 189
            ++  ++   DEGEYTC A ++ G+  CSV  +  E                   E     
Sbjct: 3119 IIDAKLN--DEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKISNIELTEGEIARFD 3176

Query: 190  AYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE--SITKRYVGE 247
               T     E +    +V   +G       D   D     ++R+ +  +  S + +   E
Sbjct: 3177 VRITGTPAPEVTWYKDEVPIEDGGRFEIYSD---DDKHSLVIRDCALSDTGSYSCKATNE 3233

Query: 248  S-DVQISTEIDRSLGPVSPPKIAQKPR-NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
            +       E+  +  PV P    + P+  +  +EG D  F+  +SG PRP V W K+   
Sbjct: 3234 AGQASCYGELTITFIPVPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAP 3293

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
            +                        S+S HY L   N    +   G      P +S    
Sbjct: 3294 I------------------------SESSHYHLHRSNDTYSLTIRGV----GPDDSGAYT 3325

Query: 366  QRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
              +       +R     IE SE K   PQF+ + Q  +VTEG+   F+C V G P P + 
Sbjct: 3326 CTATNECGMAKRTYNIDIEASEPKGSTPQFIDLMQPVEVTEGQTATFECTVKGYPRPSIE 3385

Query: 425  WFINDRQIRDDYNHKIL-VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            WF N   +++  N +I    E    +L I   T+ D G   CVARN  G+ +    L V 
Sbjct: 3386 WFKNGLPLKE--NERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLVD 3443

Query: 484  EKE 486
            E +
Sbjct: 3444 EAD 3446



 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 66/250 (26%), Positives = 109/250 (43%), Gaps = 16/250 (6%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K   PP F K++    V E    RFEV  DG P P I WY+ +  I+  P F I      
Sbjct: 2488 KRGNPPFFVKELVDIDVTEGGHERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDH 2547

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
              LI++    E++      A N  G A CS  + + EK        +PP  T    ++++
Sbjct: 2548 HTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKT-------IPPKITQRLHDLSI 2600

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             +G+ V L  K  GT    V W  + +++  +    I     T +L+++     D+G Y 
Sbjct: 2601 DAGKTVNLTVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTSSLVLVGVDTPDTGVYR 2660

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKP---KPQTKAANAP----PEIIEPLKDKIVAEGQ 4638
            C+  N AGE   +++  +++   K +P   +P     + P    P   + + DK V E  
Sbjct: 2661 CLVFNPAGEDSTNSK--ITVKGVKIEPAIQEPVEAVLSLPRGEAPSFTKKITDKQVVEND 2718

Query: 4639 AIEFSCKIVG 4648
            A+    ++ G
Sbjct: 2719 AVRLEVEVTG 2728



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 98/398 (24%), Positives = 161/398 (40%), Gaps = 46/398 (11%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
            +  V+  G P P + W R++  IK  PD   H FS        +   E+   +     N 
Sbjct: 4309 KLTVKVTGRPYPTVTWSRDDKDIK--PDDTFHMFSDD------ENPAENQGSYKCTIANE 4360

Query: 4489 GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV-------------TSGQLVRLDT 4535
             G      +L V+    QG     P  F+    + ++             TS   V +  
Sbjct: 4361 AGVRAKHFDLDVDW---QGPAPGHPYVFSSKKDDWHIFCDDNEDTAPFKFTSEGDVTMTV 4417

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            K  G   I   W+K+ K +  D +    E+DG Y+L +++   +D G Y C+A  + G +
Sbjct: 4418 KTKGRPTIT--WMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRS 4475

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEP---LKDKIVAEGQAIEFSCKIVGKPLP 4652
                E    L    D            P  ++    +  ++  EG  ++   ++ GKP P
Sbjct: 4476 ----ERRFDLRVEDDDTSTTILMDLVRPTFVKDDDMVPFQLTEEGD-VKLMVRVAGKPKP 4530

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            TV W K  K I  + + Q+S   D YTL I     +DEG YKC A NS G  +    + +
Sbjct: 4531 TVTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGIYKCTASNSVGTSSQMFDVDI 4590

Query: 4713 TQPD-----QADNLPALTPLRDIVVYE---GQPAQFKTQITSKIKPTIQWLREGALIPET 4764
               D     + D+ P+     D+  +E       +    +  K KP ++W ++    P T
Sbjct: 4591 KGTDWMLKSKDDDFPSFVDEDDVEAFEMTDEGSIRMTVIVRGKPKPEVKWSKDDK--PLT 4648

Query: 4765 PDFQMIHE--GNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            P+  ++ E   +   L+I +   +D GT+ C A   AG
Sbjct: 4649 PNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVNRAG 4686



 Score = 97.1 bits (231), Expect = 3e-19
 Identities = 114/467 (24%), Positives = 182/467 (38%), Gaps = 35/467 (7%)

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKP-PIF--TKKMQPCRV 4422
            K T K     K I  K T T   +IE  A    R V G +      P F    ++ P RV
Sbjct: 4032 KDTGKYKCIIKNIAGKATRTFDVDIE--AVKPSRHVRGELSEHLILPKFIDVTEVSPYRV 4089

Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFA 4482
                     V+  G     ++W ++   I++S  + I       +L I     +D   + 
Sbjct: 4090 SYDGDFTLTVKLSGSGD--VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYK 4147

Query: 4483 AVAENRGGTAKCSANLVVEEKRRQG----RGGIVPPSFTLTAQNV-NVTSGQLVRLDTKV 4537
             V  N+ G    S ++ +E+ R          +V P +         +T    V+L  +V
Sbjct: 4148 CVVTNKAGFDTRSFDIGLEDLRPHTFAYEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRV 4207

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
             G     V W KN + V P     +L ED  ++LLI +    D G Y+ +A N  G    
Sbjct: 4208 RGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGGINTK 4267

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
                 +    T        +   AP  + + +       G  ++ + K+ G+P PTV W 
Sbjct: 4268 RFNVDIEWDETTTTRVVDDR--EAPRFLDDGISSYEFTSGGDVKLTVKVTGRPYPTVTWS 4325

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            + DK IKP   F M   +D+      E   E++G YKC   N AG       L V     
Sbjct: 4326 RDDKDIKPDDTFHM--FSDD------ENPAENQGSYKCTIANEAGVRAKHFDLDVDWQGP 4377

Query: 4718 ADNLPALTPLR--DIVVY-----EGQPAQFKTQ------ITSKIKPTIQWLREGALIPET 4764
            A   P +   +  D  ++     +  P +F ++      + +K +PTI W+++  +I + 
Sbjct: 4378 APGHPYVFSSKKDDWHIFCDDNEDTAPFKFTSEGDVTMTVKTKGRPTITWMKDEKIITQD 4437

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              F    +     L +    EED G +TC A T  G+ E    L V+
Sbjct: 4438 NKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSERRFDLRVE 4484



 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 56/210 (26%), Positives = 90/210 (42%), Gaps = 1/210 (0%)

Query: 371  ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430
            I +   R   E+     K + P+F    +D +V EG        VTG P PEV WF + +
Sbjct: 2179 IAEEDLRIDVEQTAALPKPIPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGK 2238

Query: 431  QIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489
             +    + +  V   G  + L+I     SD+G   C A N +GE    C ++V+      
Sbjct: 2239 PVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKE 2298

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
             PKF      + + EG     + +  G+P P++ W  +G  + P   + I  D   S+L 
Sbjct: 2299 PPKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLI 2358

Query: 550  IPRAKASDAAWYQCTAQNVAGSTATRARLY 579
            +       +  Y C A+N  G   + ARL+
Sbjct: 2359 LMHCPLDLSGKYTCVAENEVGQVQSAARLH 2388



 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 79/316 (25%), Positives = 131/316 (41%), Gaps = 11/316 (3%)

Query: 66   PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            P + + P F Q  +     +G     E ++ G P PVV W  K   LV+ +  S+   E 
Sbjct: 2958 PTDEAGPKFLQRLELKEVVEGSRTDLEVEVSGKPKPVVEWL-KDGELVKPS--SLMTLET 3014

Query: 126  TGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184
             G V +L I      DEGEYTC A+N+ GE  C+  +  E               + +  
Sbjct: 3015 EGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEG 3074

Query: 185  TV---EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
             +   E +  G  G   E  R  + +            D  V T     L +      + 
Sbjct: 3075 KMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVA 3134

Query: 242  KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
                G+    +   +D +   V PP+  +K  N +L EG  A+F V+++G P P VTW+K
Sbjct: 3135 TSKAGKDSCSVELLVDEA---VVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYK 3191

Query: 302  NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE-SPTE 360
            +   + +  + EI +  +  +L +R+   SD+G Y+  A N  G     G L +   P  
Sbjct: 3192 DEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTITFIPVP 3251

Query: 361  SYVQDQRSQYITDTQQ 376
             +  ++  +  TD ++
Sbjct: 3252 PHFTEEAPKIPTDFEE 3267



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 145/622 (23%), Positives = 248/622 (39%), Gaps = 80/622 (12%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV--QQGHRFKTTYDFGYV 2035
            P+  + + +  +  G  V+L  T+     P   V+W+ +   +  + G   +T++     
Sbjct: 2589 PKITQRLHDLSIDAGKTVNL--TVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTS-- 2644

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
            +L ++     DTG Y C   N  GE  T S + V    G+ ++   ++ ++ +  L +  
Sbjct: 2645 SLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITV---KGVKIEPAIQEPVEAVLSLPR-- 2699

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPI-NDPHLTIDWFHNGQKIRA 2154
                      G+ P F   +T  + + E D    E  V    ++P  T D   N Q  R 
Sbjct: 2700 ----------GEAPSFTKKITD-KQVVENDAVRLEVEVTGFTHEPVFTAD---NWQTKRR 2745

Query: 2155 GHRYRTTHDFGYVAL-DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILD--- 2210
              R R+   F    L D+ +   ++ G Y     +KL  A+++       + ++      
Sbjct: 2746 CIRERSEFLFNNKLLSDVSFRVGKEQGKYFIPG-HKLILAISSPVFYAMFYGSMAEQKAE 2804

Query: 2211 -TQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPV 2269
             T   +  +   +L    +     + E  +    ++ +      + + K A FE  VE  
Sbjct: 2805 ITVADSDADSFMELLRYAYFDEATINEENVLGVLYLAKKYILPFLADNK-AIFE--VEIT 2861

Query: 2270 HDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSA 2329
              P  ++E+  N   ++S  RF    D    +L ++    +D GE    A N+ G  TS 
Sbjct: 2862 GKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSM 2921

Query: 2330 ISMTVTAKGSIISESQ-RPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNI 2388
             S+ V  K S  +E   +P G E + E++   PF+     EP     P F Q L+ +  +
Sbjct: 2922 ASLIVRDKPSEQTELYIKPVGQEPV-EMQFQVPFET----EPTDEAGPKFLQRLE-LKEV 2975

Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGV 2448
             EG     +  +   G P   VEW ++ +L++ SS +T   +    ++TI +   +DEG 
Sbjct: 2976 VEGSRTDLEVEVS--GKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGE 3033

Query: 2449 YMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKP 2508
            Y C A N +GE                 E    EGM+               P +   KP
Sbjct: 3034 YTCIAKNKVGEVSCTA------------ELLVEEGMR---------------PPQFIVKP 3066

Query: 2509 IFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTL 2568
               Q++ G       + A +EARV   G P    EW  +G  +K G RF+   +     L
Sbjct: 3067 SSLQIMEG-------KMAKFEARV--SGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVL 3117

Query: 2569 DINSVVANDAGLYMCKAINRAG 2590
             I     ND G Y C A ++AG
Sbjct: 3118 TIIDAKLNDEGEYTCVATSKAG 3139



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 91/333 (27%), Positives = 138/333 (41%), Gaps = 43/333 (12%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            RPP+F  V    + I EG++A +EA +  +G     +EW  +G+ I+   R +  +    
Sbjct: 3058 RPPQFI-VKPSSLQIMEGKMAKFEARV--SGLPGPEVEWLRDGRPIKPGRRFQIEFEKDR 3114

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
             VL I+  K  D G Y+C AT+K G+   SV+L  VD++    P F   I NIE L +G+
Sbjct: 3115 SVLTIIDAKLNDEGEYTCVATSKAGKDSCSVEL-LVDEAV-VPPEFVRKISNIE-LTEGE 3171

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
             A F+  +     P+  + WY +  P+    R +  SD     L I      D+G Y C+
Sbjct: 3172 IARFDVRITGTPAPE--VTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCK 3229

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFI 3285
            A N+ G+       +CYG+  +    + P                       + E PK  
Sbjct: 3230 ATNEAGQ------ASCYGELTITFIPVPPHF---------------------TEEAPKIP 3262

Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDIL 3345
            T  +      EG    FEA +     PD  VEW  +   +     Y          L I 
Sbjct: 3263 TDFE------EGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDTYSLTIR 3314

Query: 3346 YCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
                ++SG Y C ATN+ G      N+   + E
Sbjct: 3315 GVGPDDSGAYTCTATNECGMAKRTYNIDIEASE 3347



 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 60/196 (30%), Positives = 86/196 (43%), Gaps = 7/196 (3%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            VT    +++  KVTG     V WLK+ + V  D   K+ EED  Y+L I E    D G Y
Sbjct: 4861 VTEEGDIKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMY 4920

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
                 N  G      +  V    T    +   +      +   P +     EG  +  S 
Sbjct: 4921 TVKITNDVGSGTRTFDVKVE-DTTTSLFEGTVRPKFIEDDSFVPFES--TEEGN-VRLSV 4976

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            KI GKP+P V W K +K +   +  ++    D YTL I EA P D G YKC   N AG+ 
Sbjct: 4977 KITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKS 5036

Query: 4705 TVAAKLKV---TQPDQ 4717
            T    +++   T+P++
Sbjct: 5037 TRTFSVEIEGETKPEK 5052



 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 51/178 (28%), Positives = 81/178 (45%), Gaps = 2/178 (1%)

Query: 402  DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
            D  EG    F+  V+GRP P+V W  ++  I +  +H  L   +  ++L I  V   DSG
Sbjct: 3264 DFEEGGDITFEATVSGRPRPDVEWHKDEAPISES-SHYHLHRSNDTYSLTIRGVGPDDSG 3322

Query: 462  VVTCVARNKSGETAFQCRLNVIEKE-QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
              TC A N+ G       +++   E +   P+F++    + V EG+         G P P
Sbjct: 3323 AYTCTATNECGMAKRTYNIDIEASEPKGSTPQFIDLMQPVEVTEGQTATFECTVKGYPRP 3382

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I W K+G+P+  N  +    +G  S+L I +    D   Y+C A+N  G  +    L
Sbjct: 3383 SIEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATEL 3440



 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 64/236 (27%), Positives = 107/236 (45%), Gaps = 6/236 (2%)

Query: 4394 AQTQERVVEGPV-KPSKPPIF--TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP 4450
            A+ ++ ++E  + KP + PIF  T +++P  V E    +  V+  G+P P ++W +++ P
Sbjct: 4830 ARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVTGKPKPSVEWLKDDRP 4889

Query: 4451 IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG 4510
            + +    ++        L IR+    D  ++     N  G+   + ++ VE+       G
Sbjct: 4890 VLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFEG 4949

Query: 4511 IVPPSFTLTAQNVNVTSGQL--VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568
             V P F      V   S +   VRL  K+TG    +V W K+ K V      ++  +D  
Sbjct: 4950 TVRPKFIEDDSFVPFESTEEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDI 5009

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPE 4624
            YTL I EA P DSG Y+C   N AG++       +      +K KP T+    P E
Sbjct: 5010 YTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKP-TEREGKPLE 5064



 Score = 89.4 bits (212), Expect = 6e-17
 Identities = 60/188 (31%), Positives = 88/188 (46%), Gaps = 7/188 (3%)

Query: 3047 PPEFTTVFKDI-VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PP FT     I  D  EG    +EA++  +G     +EW  +   I  S       +   
Sbjct: 3251 PPHFTEEAPKIPTDFEEGGDITFEATV--SGRPRPDVEWHKDEAPISESSHYHLHRSNDT 3308

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDG 3164
              L I G    DSG Y+C ATN+ G A+ +  ++    + KG  P+F   +Q +E + +G
Sbjct: 3309 YSLTIRGVGPDDSGAYTCTATNECGMAKRTYNIDIEASEPKGSTPQFIDLMQPVE-VTEG 3367

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            Q+A FECTV     P   IEW+ NG P++ + RI +  +     L I      D G Y C
Sbjct: 3368 QTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKC 3425

Query: 3225 RAYNKYGE 3232
             A N +G+
Sbjct: 3426 VARNSFGK 3433



 Score = 86.6 bits (205), Expect = 4e-16
 Identities = 73/311 (23%), Positives = 136/311 (43%), Gaps = 42/311 (13%)

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDS 333
            +++ E  D + +V++ G+P+P V W K+ + +I+S  H ++++H    TL + +  + D 
Sbjct: 3656 AEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIISS-PHFMVSSHADVHTLVINSPNQDDI 3714

Query: 334  GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393
            G Y ++A N  G    +  + VE   +    + R+ ++      + E+R  +S       
Sbjct: 3715 GQYKVIASNHRGMASRTFDVNVEGAND----EMRASFV------DMEDRGPLS------- 3757

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI---------LVNE 444
               + +D D+        + ++ G P P+V W+ +D  + +    KI          + +
Sbjct: 3758 ---ITEDGDLV------LEVKIKGEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVTIKD 3808

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV--ERFSTLNV 502
            +     + TN+T +D G  T + R      +   +L    K     P+FV  E  S   V
Sbjct: 3809 ANKEDSVFTNIT-NDFG--TAIRRFSIDVESVMPKLQGFVKRDEDFPQFVNVEGVSPFEV 3865

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
                 + L  R  G P P ++W KDG+P++PN  +  H       L I       A  Y+
Sbjct: 3866 TSEGDIKLQTRVTGFPEPDVSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLYAGTYK 3925

Query: 563  CTAQNVAGSTA 573
            C A N  G+ +
Sbjct: 3926 CVATNRRGTNS 3936



 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 112/497 (22%), Positives = 197/497 (39%), Gaps = 32/497 (6%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T  P  T  + D+ +   +  +   +    G P+  V+W  +   I   + +        
Sbjct: 2586 TIPPKITQRLHDLSIDAGKTVNLTVKFF--GTPEPLVKWFMDDEEITNEDGVDIETSHCT 2643

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             +L +  V+  D+G Y C   N  GE  T+S + V+         +   A+  + + E  
Sbjct: 2644 SSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKGVKIEPAIQEPVEAVLSLPRGEAP 2703

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887
            S  ++  D +V  N A R   ++ G T      + +++ +     +   R E+ FN K+L
Sbjct: 2704 SFTKKITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQTKRRCIRE---RSEFLFNNKLL 2760

Query: 1888 QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINN-LGQAVSSIRLNVQSKESIIRDS 1946
             S   +R   + G   +          G     AI++ +  A+    +  Q  E  + DS
Sbjct: 2761 -SDVSFRVGKEQGKYFI---------PGHKLILAISSPVFYAMFYGSMAEQKAEITVADS 2810

Query: 1947 QHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND 2006
              +S +E ++Y    + +  A  ++  V+      K      + +   +  E  +T    
Sbjct: 2811 DADSFMELLRY----AYFDEATINEENVLGVLYLAKKYILPFLADNKAI-FEVEIT--GK 2863

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P  +VEW  N   ++ G RF+   D     L +  +  +D G   C ATN+ G   + +S
Sbjct: 2864 PEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSMAS 2923

Query: 2067 VKVDAKSGLYLDTLDEQRLKKI-QELEKYERPKPIEEEQPGQR-PVFLTALTSLENLKEG 2124
            + V  K         E  +K + QE  + +   P E E   +  P FL  L  L+ + EG
Sbjct: 2924 LIVRDKP----SEQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRL-ELKEVVEG 2978

Query: 2125 DRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMC 2184
             R   E  VE    P   ++W  +G+ ++         +     L I+ T  +D G Y C
Sbjct: 2979 SRTDLE--VEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTC 3036

Query: 2185 KATNKLGEAVNTCTLKV 2201
             A NK+GE   T  L V
Sbjct: 3037 IAKNKVGEVSCTAELLV 3053



 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 71/303 (23%), Positives = 130/303 (42%), Gaps = 31/303 (10%)

Query: 282  DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLA 340
            D + Q +++G P P V+WFK+G  ++  N+H +    +    L +++     +G Y  +A
Sbjct: 3870 DIKLQTRVTGFPEPDVSWFKDGIPVV-PNEHIVYHIRDDVHILIIKSPTPLYAGTYKCVA 3928

Query: 341  ENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQD 400
             N  G       + +E+        + +++IT  Q  ET     I +   AP   ++ ++
Sbjct: 3929 TNRRGTNSRDFEVTIET-------GEAAEHITFQQDEETVRAQFIEKGPYAPVPFEITEE 3981

Query: 401  RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
             DV      +   R+ G P+PE+ WF + R +  D +H  + ++   + ++I   T+ D+
Sbjct: 3982 GDV------KLQVRICGIPFPEIDWFKDGRHLSPD-DHIKITSDDDLYTVLIRQPTIKDT 4034

Query: 461  GVVTCVARNKSGET--AFQCRLNVIE---------KEQVVAPKFVE--RFSTLNVREGEP 507
            G   C+ +N +G+    F   +  ++          E ++ PKF++    S   V     
Sbjct: 4035 GKYKCIIKNIAGKATRTFDVDIEAVKPSRHVRGELSEHLILPKFIDVTEVSPYRVSYDGD 4094

Query: 508  VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
              L  +  G+    + W KDG  I  +    I  D     L I  A   D   Y+C   N
Sbjct: 4095 FTLTVKLSGSGD--VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTN 4152

Query: 568  VAG 570
             AG
Sbjct: 4153 KAG 4155



 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 106/507 (20%), Positives = 192/507 (37%), Gaps = 44/507 (8%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            PPKI Q+  +  +  G      V+  G P P V WF + + + N +  +I T+H  ++L 
Sbjct: 2588 PPKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTSSLV 2647

Query: 325  VRNTQKSDSGHYTLLAENPNGCIVTSGYL---------AVESPTESYVQDQRSQY----- 370
            +      D+G Y  L  NP G   T+  +         A++ P E+ +   R +      
Sbjct: 2648 LVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKGVKIEPAIQEPVEAVLSLPRGEAPSFTK 2707

Query: 371  -ITDTQQRETEE-RIEISEKALAPQFVKVCQDRDVTEGKMT-RFDCRVTGRPYPEVTWFI 427
             ITD Q  E +  R+E+       + V    +       +  R +     +   +V++ +
Sbjct: 2708 KITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQTKRRCIRERSEFLFNNKLLSDVSFRV 2767

Query: 428  NDRQIRDDY-NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN----- 481
               Q +     HK+++  S      +   ++++      VA + +       R       
Sbjct: 2768 GKEQGKYFIPGHKLILAISSPVFYAMFYGSMAEQKAEITVADSDADSFMELLRYAYFDEA 2827

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
             I +E V+   ++ +   L        +      G P P++ W K+ V I         +
Sbjct: 2828 TINEENVLGVLYLAKKYILPFLADNKAIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRS 2887

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKV 601
            DG   TL +  ++  D    +CTA N   S  T   +           Q  L++ +P   
Sbjct: 2888 DGTVYTLTLRGSRLDDEGEIKCTATN---SAGTVTSMASLIVRDKPSEQTELYI-KPVG- 2942

Query: 602  XXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIE 661
                          +     +  +P   E      P+F+  L+    +EG +   E  +E
Sbjct: 2943 --------------QEPVEMQFQVPFETEPTDEAGPKFLQRLELKEVVEGSRTDLE--VE 2986

Query: 662  PVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
              G P   +EWLK+G+ ++ SS  T        +L +++  + D GEYTC A +  G   
Sbjct: 2987 VSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVS 3046

Query: 722  TKAVLHVTPRATIERTSQHPETLQYIQ 748
              A L V       +    P +LQ ++
Sbjct: 3047 CTAELLVEEGMRPPQFIVKPSSLQIME 3073



 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 72/310 (23%), Positives = 130/310 (41%), Gaps = 28/310 (9%)

Query: 276  KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335
            ++ E  D + QV++ G P P + WFK+G+ L   +  +I +  +  T+ +R     D+G 
Sbjct: 3977 EITEEGDVKLQVRICGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGK 4036

Query: 336  YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395
            Y  + +N  G    +  + +E+        + S+++          R E+SE  + P+F+
Sbjct: 4037 YKCIIKNIAGKATRTFDVDIEAV-------KPSRHV----------RGELSEHLILPKFI 4079

Query: 396  KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
             V +           F   V      +V W + D ++ +D    ++  +   H L I   
Sbjct: 4080 DVTEVSPYRVSYDGDFTLTVKLSGSGDVQW-MKDGEVIEDSKRYVIRQDDDLHMLTILGA 4138

Query: 456  TLSDSGVVTCVARNKSG--ETAFQCRLNVI-------EKEQVVAPKFVERFST-LNVREG 505
            T  D G   CV  NK+G    +F   L  +       E  ++VAP ++E   T   + + 
Sbjct: 4139 TEDDLGTYKCVVTNKAGFDTRSFDIGLEDLRPHTFAYEPSELVAPYYLEDGVTAFQMTDA 4198

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              V L  R  G P P + W K+  P++P+    +  +    +L I +   +D   Y+  A
Sbjct: 4199 GDVKLTVRVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIA 4258

Query: 566  QNVAGSTATR 575
             N  G    R
Sbjct: 4259 TNEGGINTKR 4268



 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 61/203 (30%), Positives = 94/203 (46%), Gaps = 7/203 (3%)

Query: 660  IEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
            +E  G P  K+EWLKN   IE+  RF         +L +    + D GE  C A ++ G 
Sbjct: 2858 VEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGT 2917

Query: 720  AETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDL 779
              + A L V  + + E+T  +   ++ + Q     ++Q     E      P+F++ L +L
Sbjct: 2918 VTSMASLIVRDKPS-EQTELY---IKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRL-EL 2972

Query: 780  GELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAED 839
             E+ EG     E +++    P   VEW KDG  +  SS +T        +L IM+   +D
Sbjct: 2973 KEVVEGSRTDLEVEVSGKPKPV--VEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDD 3030

Query: 840  AGSYTVRAVNKLGEAISTASIRV 862
             G YT  A NK+GE   TA + V
Sbjct: 3031 EGEYTCIAKNKVGEVSCTAELLV 3053



 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 57/206 (27%), Positives = 98/206 (47%), Gaps = 8/206 (3%)

Query: 3029 EDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG 3088
            E+ LR +  Q        PPEF +  +DI +++EG        +  TG     ++WF +G
Sbjct: 2181 EEDLRIDVEQTAALPKPIPPEFKSALRDI-EVNEGNTVTLRIHV--TGSPKPEVDWFKDG 2237

Query: 3089 KTIEA-SHRIRTVYAFGMV-VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKG 3146
            K +    HR   V   G V  L I   + +D+G Y C+A N  G+   S  ++ +  +  
Sbjct: 2238 KPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPK 2297

Query: 3147 QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGF 3206
            + P+F  ++++I  + +G S  F+  V     P+ K+ WYHNG+ ++    +  V D   
Sbjct: 2298 EPPKFERNLKDIT-IAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEH 2354

Query: 3207 VVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              L + +     SG+Y C A N+ G+
Sbjct: 2355 SSLILMHCPLDLSGKYTCVAENEVGQ 2380



 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 61/200 (30%), Positives = 91/200 (45%), Gaps = 11/200 (5%)

Query: 385  ISEKALAPQFVKVCQDR--DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            +S+    P F++  + +  +VTE    +   +VTG+P P V W  +DR +  D +H  + 
Sbjct: 4841 LSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVTGKPKPSVEWLKDDRPVLSD-SHIKMT 4899

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNK--SGETAFQCRLNVIEK---EQVVAPKFVE-- 495
             E   ++L I   T SD G+ T    N   SG   F  ++        E  V PKF+E  
Sbjct: 4900 EEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFEGTVRPKFIEDD 4959

Query: 496  RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
             F      E   V L+ +  G P P ++W KD  P+     +R+       TL I  A  
Sbjct: 4960 SFVPFESTEEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATP 5019

Query: 556  SDAAWYQCTAQNVAG-STAT 574
            +D+  Y+CT  N AG ST T
Sbjct: 5020 NDSGSYKCTLTNDAGKSTRT 5039



 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 2/137 (1%)

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA-PPEIIEPLKDKIVAEGQAI 4640
            G Y+ V + S G +R D   V      K +   +    +  PP   +PLKDK V EG+  
Sbjct: 1992 GMYKVVRLRSDG-SRGDEMWVPPNVLQKKRSTAEIMMGDIQPPFFQKPLKDKEVKEGKPF 2050

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            +   KI   P   V+W K  + +KP  +F+  R  D Y L I EA  EDEG Y+C A N+
Sbjct: 2051 KLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNN 2110

Query: 4701 AGRVTVAAKLKVTQPDQ 4717
            AGR +  A + V   D+
Sbjct: 2111 AGRASTEADILVESADE 2127



 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 58/216 (26%), Positives = 98/216 (45%), Gaps = 10/216 (4%)

Query: 1722 VAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSG 1781
            +A+N+A  FE  +   G P+ +VEWL+N V IE+ +R     D     L ++    +D G
Sbjct: 2849 LADNKAI-FEVEI--TGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEG 2905

Query: 1782 TYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVN 1841
               C A N  G   + ++L V+ K S     Q E  ++ + Q     ++Q   + E    
Sbjct: 2906 EIKCTATNSAGTVTSMASLIVRDKPS----EQTELYIKPVGQEPVEMQFQVPFETEPTDE 2961

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
              P+F+ +L    ++ EG     E  +   P P   VEW  +G++++         +   
Sbjct: 2962 AGPKFLQRLE-LKEVVEGSRTDLEVEVSGKPKP--VVEWLKDGELVKPSSLMTLETEGQV 3018

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
              L I+    +D GEYTC A N +G+   +  L V+
Sbjct: 3019 HTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVE 3054



 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 93/368 (25%), Positives = 152/368 (41%), Gaps = 33/368 (8%)

Query: 4411 PIFTKK--MQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            P F K   M P ++ E    +  V   G+P P + W +++ PI  +   Q+  +     L
Sbjct: 4499 PTFVKDDDMVPFQLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTYTL 4558

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP-PSFT--LTAQNVNV 4525
            II+    +D  ++   A N  GT+    ++ ++      +      PSF      +   +
Sbjct: 4559 IIKSPTDKDEGIYKCTASNSVGTSSQMFDVDIKGTDWMLKSKDDDFPSFVDEDDVEAFEM 4618

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKY 4584
            T    +R+   V G    +V W K+ K + P+  N ++EE D TYTL+I      D G Y
Sbjct: 4619 TDEGSIRMTVIVRGKPKPEVKWSKDDKPLTPN-SNIVMEEMDDTYTLVIKSPSSDDRGTY 4677

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
            +C A+N AG    +    V    T+D  +   +       +I   KD    EG +I F  
Sbjct: 4678 KCTAVNRAG---TNIRSFVVNVNTEDSTQRDQRQM-----VIR--KD----EG-SITFE- 4721

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             + G  +     +  D    P +     R  D +TL I E  P D G YKC   +  GR 
Sbjct: 4722 DVPGNIIRPK--FTEDGSFVPFQSTNEDRQDDTHTLTIREPSPNDTGSYKCTISSDYGRS 4779

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
            T    +++   D  +  PA      +  +  +P   +T   +KI   +Q   E AL P  
Sbjct: 4780 TRTFNVEI-DSDMPE--PAQPDYPKVEPFHEKPLSEETMSVTKI---LQ--DEKALEPAR 4831

Query: 4765 PDFQMIHE 4772
            P+  +I +
Sbjct: 4832 PEKNIIED 4839



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 72/306 (23%), Positives = 120/306 (39%), Gaps = 34/306 (11%)

Query: 276  KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335
            K     D    V+  G  RP +TW K+ + +   NK          +L V    + D G 
Sbjct: 4406 KFTSEGDVTMTVKTKG--RPTITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGL 4463

Query: 336  YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395
            YT +AE  +G                     RS+   D +  + +    I    + P FV
Sbjct: 4464 YTCIAETTDG---------------------RSERRFDLRVEDDDTSTTILMDLVRPTFV 4502

Query: 396  KVCQ--DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            K        +TE    +   RV G+P P VTW  + + I +  + ++ V +   + L+I 
Sbjct: 4503 KDDDMVPFQLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDD-TYTLIIK 4561

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNV------IEKEQVVAPKFVER--FSTLNVREG 505
            + T  D G+  C A N  G ++    +++      ++ +    P FV+        + + 
Sbjct: 4562 SPTDKDEGIYKCTASNSVGTSSQMFDVDIKGTDWMLKSKDDDFPSFVDEDDVEAFEMTDE 4621

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              + +     G P P + W KD  P+ PN  + +       TL I    + D   Y+CTA
Sbjct: 4622 GSIRMTVIVRGKPKPEVKWSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTA 4681

Query: 566  QNVAGS 571
             N AG+
Sbjct: 4682 VNRAGT 4687



 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 80/316 (25%), Positives = 133/316 (42%), Gaps = 40/316 (12%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            + E  D   +V++ G P P V W+K+   L  + + +I    +   + +++  K DS   
Sbjct: 3758 ITEDGDLVLEVKIKGEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVTIKDANKEDSVFT 3817

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
             +   N  G  +    + VES     V  +   ++    +R+ +           PQFV 
Sbjct: 3818 NIT--NDFGTAIRRFSIDVES-----VMPKLQGFV----KRDED----------FPQFVN 3856

Query: 397  V--CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
            V      +VT     +   RVTG P P+V+WF +   +  +  H +       H L+I +
Sbjct: 3857 VEGVSPFEVTSEGDIKLQTRVTGFPEPDVSWFKDGIPVVPN-EHIVYHIRDDVHILIIKS 3915

Query: 455  VTLSDSGVVTCVARNKSGETA--FQCRLNVIEK---------EQVVAPKFVERFS----T 499
             T   +G   CVA N+ G  +  F+  +   E          E+ V  +F+E+       
Sbjct: 3916 PTPLYAGTYKCVATNRRGTNSRDFEVTIETGEAAEHITFQQDEETVRAQFIEKGPYAPVP 3975

Query: 500  LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
              + E   V L  R  G P P I W KDG  + P+  ++I +D    T+ I +    D  
Sbjct: 3976 FEITEEGDVKLQVRICGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTG 4035

Query: 560  WYQCTAQNVAGSTATR 575
             Y+C  +N+AG  ATR
Sbjct: 4036 KYKCIIKNIAGK-ATR 4050



 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 73/251 (29%), Positives = 107/251 (42%), Gaps = 41/251 (16%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            EE L    E T    KP PP F   ++D I+V EG  V    R+   G P   +DWF +G
Sbjct: 2181 EEDLRIDVEQTAALPKPIPPEFKSALRD-IEVNEGNTVTL--RIHVTGSPKPEVDWFKDG 2237

Query: 3736 RPFA-TGSRVHTLNDFGFI-ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
            +P +    R   +   G +  L I      D G+Y C+A N  G      ++T S   D+
Sbjct: 2238 KPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAG------EVTSSCNVDV 2291

Query: 3794 VLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRV 3853
                                  +  APKE      PPKF   +K  T+ E    RF+ +V
Sbjct: 2292 ----------------------LHVAPKE------PPKFERNLKDITIAEGCSTRFDVQV 2323

Query: 3854 EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
                +PK  + WY NGKL+        V+D    SL +++   + SG+Y C A N+ G+ 
Sbjct: 2324 TGSPEPK--VFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCVAENEVGQV 2381

Query: 3914 FTKATISCKKL 3924
             + A +   +L
Sbjct: 2382 QSAARLHITEL 2392



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 9/200 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP+F    KDI  I+EG    ++  +  TG     + W++NGK ++    +  V+     
Sbjct: 2299 PPKFERNLKDIT-IAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHS 2355

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L ++      SG Y+C A N+ GQ + + +L   + +   +P+F   + N+  +  G +
Sbjct: 2356 SLILMHCPLDLSGKYTCVAENEVGQVQSAARLHITELAI--QPKFAERLTNVS-ISSGDT 2412

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV-VLDIAYTQNHDSGEYVCR 3225
               EC V     P  ++ W+ + + +R  +R    +  G V VL I      D G Y C 
Sbjct: 2413 IVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCI 2470

Query: 3226 AYNKYGEDFTRATINCYGKG 3245
            A N  G+D T A +    +G
Sbjct: 2471 ATNPAGQDDTVAELTVAKRG 2490



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 50/156 (32%), Positives = 76/156 (48%), Gaps = 13/156 (8%)

Query: 4499 VVEEKRRQGR---GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            V+++KR       G I PP F    ++  V  G+  +LD K+T     +V WLK+G+ ++
Sbjct: 2015 VLQKKRSTAEIMMGDIQPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLK 2074

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP--K 4613
            P    K      TY L+I EA  +D G+Y C A+N+AG A  +A+ +V       +P  +
Sbjct: 2075 PGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDE 2134

Query: 4614 PQ-----TKA---ANAPPEIIEPLKDKIVAEGQAIE 4641
            PQ     TK       PP +   L  K   + QA+E
Sbjct: 2135 PQQMEQSTKTIAIGQEPPAVTLTLDGKAGFDFQAVE 2170



 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 49/209 (23%), Positives = 91/209 (43%), Gaps = 10/209 (4%)

Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672
            KP+ +      + ++P +  +  EG  I+ + K+ GKP P+V+W K D+ +    + +M+
Sbjct: 4843 KPKQEPIFIETDEVKPFE--VTEEGD-IKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMT 4899

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV----TQPDQADNLPALTPLR 4728
               D Y+L I E    DEG Y     N  G  T    +KV    T   +    P      
Sbjct: 4900 EEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFEGTVRPKFIEDD 4959

Query: 4729 DIVVYEGQP---AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
              V +E       +   +IT K  P + W ++   + +  + ++ H+ +   L I     
Sbjct: 4960 SFVPFESTEEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATP 5019

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             D+G++ C  T  AG+   +  + ++ +T
Sbjct: 5020 NDSGSYKCTLTNDAGKSTRTFSVEIEGET 5048



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 13/179 (7%)

Query: 404  TEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV 463
            +EG +T    +  GRP   +TW  +++ I  D N  +   + G ++L +   T  D G+ 
Sbjct: 4409 SEGDVT-MTVKTKGRP--TITWMKDEKIITQD-NKFLFTEDDGIYSLTVVKPTEEDRGLY 4464

Query: 464  TCVARNKSGETAFQCRLNVIEKE-------QVVAPKFV--ERFSTLNVREGEPVVLNARA 514
            TC+A    G +  +  L V + +        +V P FV  +      + E   V L  R 
Sbjct: 4465 TCIAETTDGRSERRFDLRVEDDDTSTTILMDLVRPTFVKDDDMVPFQLTEEGDVKLMVRV 4524

Query: 515  VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
             G P P +TW KD  PI     +++       TL I      D   Y+CTA N  G+++
Sbjct: 4525 AGKPKPTVTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGIYKCTASNSVGTSS 4583



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 72/317 (22%), Positives = 124/317 (39%), Gaps = 49/317 (15%)

Query: 276  KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335
            ++ +  D +  V++ G P+P V W KN + ++ S+   ++   +  +L +R   K+D G 
Sbjct: 4194 QMTDAGDVKLTVRVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGV 4253

Query: 336  YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395
            Y ++A N  G                       ++  D +  ET     + ++  AP+F+
Sbjct: 4254 YKVIATNEGGI-------------------NTKRFNVDIEWDETTTTRVVDDRE-APRFL 4293

Query: 396  KV-CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR-DDYNHKILVNESGNHALMIT 453
                   + T G   +   +VTGRPYP VTW  +D+ I+ DD  H  + ++  N A    
Sbjct: 4294 DDGISSYEFTSGGDVKLTVKVTGRPYPTVTWSRDDKDIKPDDTFH--MFSDDENPA---- 4347

Query: 454  NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV---------------ERFS 498
                 + G   C   N++G  A    L+V  +       +V               E  +
Sbjct: 4348 ----ENQGSYKCTIANEAGVRAKHFDLDVDWQGPAPGHPYVFSSKKDDWHIFCDDNEDTA 4403

Query: 499  TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
                     V +  +  G PT  ITW KD   I  + +     D G  +L + +    D 
Sbjct: 4404 PFKFTSEGDVTMTVKTKGRPT--ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDR 4461

Query: 559  AWYQCTAQNVAGSTATR 575
              Y C A+   G +  R
Sbjct: 4462 GLYTCIAETTDGRSERR 4478



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 121/610 (19%), Positives = 213/610 (34%), Gaps = 69/610 (11%)

Query: 276  KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335
            +L E  D +  V+++G P+P VTW K+ + +  ++  ++    +  TL +++    D G 
Sbjct: 4511 QLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGI 4570

Query: 336  YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395
            Y   A N  G   +S    V+     ++   +          +  E  E+++        
Sbjct: 4571 YKCTASNSVG--TSSQMFDVDIKGTDWMLKSKDDDFPSFVDEDDVEAFEMTD-------- 4620

Query: 396  KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
                     EG + R    V G+P PEV W  +D+ +  + N  ++      + L+I + 
Sbjct: 4621 ---------EGSI-RMTVIVRGKPKPEVKWSKDDKPLTPNSNI-VMEEMDDTYTLVIKSP 4669

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
            +  D G   C A N++G       +NV  ++        +R   +   EG  +       
Sbjct: 4670 SSDDRGTYKCTAVNRAGTNIRSFVVNVNTEDSTQRD---QRQMVIRKDEGS-ITFEDVPG 4725

Query: 516  GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
                P+ T  +DG   +P             TL I     +D   Y+CT  +  G  +TR
Sbjct: 4726 NIIRPKFT--EDG-SFVPFQSTNEDRQDDTHTLTIREPSPNDTGSYKCTISSDYG-RSTR 4781

Query: 576  ARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGE--EDRV 633
                          Q       P                L+  +   P  P     ED +
Sbjct: 4782 TFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEETMSVTKILQDEKALEPARPEKNIIEDVL 4841

Query: 634  YPP---PQFIV--PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
              P   P FI    +K     E G I    ++   G P   +EWLK+ + + + S     
Sbjct: 4842 SKPKQEPIFIETDEVKPFEVTEEGDIKMTVKV--TGKPKPSVEWLKDDRPVLSDSHIKMT 4899

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ 748
                  SL +      D G YT +  +  G                        T  +  
Sbjct: 4900 EEDDIYSLTIREPTKSDEGMYTVKITNDVGSG----------------------TRTFDV 4937

Query: 749  QLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYK 808
            ++ED +    + ++  +  +   F+ P +     +EG N     ++T    P   V W K
Sbjct: 4938 KVEDTTTSLFEGTVRPKFIEDDSFV-PFE---STEEG-NVRLSVKIT--GKPVPEVSWTK 4990

Query: 809  DGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
            D +P+     I         +L I      D+GSY     N  G++  T S+ +   +  
Sbjct: 4991 DEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGET-- 5048

Query: 869  TADLGIPEQR 878
              + G P +R
Sbjct: 5049 KPEKGKPTER 5058



 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 79/309 (25%), Positives = 124/309 (40%), Gaps = 41/309 (13%)

Query: 768  QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827
            Q P F +PL+D  E++EG+    + ++T +  P   V+W KDG P+       +  +   
Sbjct: 2031 QPPFFQKPLKDK-EVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXX 887
              L I     ED G Y   AVN  G A + A I V +    +     P+Q     KT   
Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAI 2147

Query: 888  XXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGF-------------AHFEARLE 934
                               Q  E K P  D+I+ ++                  F++ L 
Sbjct: 2148 GQEPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSALR 2207

Query: 935  PI----GDS-TLRV----------EWLKDGRPVEASSRITTFFNFGYV----ALTIKSVT 975
             I    G++ TLR+          +W KDG+PV  S      F  G V     L IK   
Sbjct: 2208 DIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPV--SGLPHRRFEVGCVGEVYTLVIKEAR 2265

Query: 976  VHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEE 1035
              D G Y C+AYN+ G+ T+S N+ ++     +A  + P     ++ +  A   S R + 
Sbjct: 2266 GSDTGKYLCKAYNSAGEVTSSCNVDVLH----VAPKEPPKFERNLKDITIAEGCSTRFDV 2321

Query: 1036 EVKITQKPR 1044
            +V  + +P+
Sbjct: 2322 QVTGSPEPK 2330



 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 57/206 (27%), Positives = 90/206 (43%), Gaps = 11/206 (5%)

Query: 933  LEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ 992
            +E  G    +VEWLK+   +E+  R     +     LT++   + D G   C A N+ G 
Sbjct: 2858 VEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGT 2917

Query: 993  ATTSANLTIVTKKDIIAESQ-HPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKG 1051
             T+ A+L +  K     E    P G E ++        ++ T+E       P+FL  L+ 
Sbjct: 2918 VTSMASLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDE-----AGPKFLQRLE- 2971

Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV-ALDIASVRA 1110
              ++VEG     E  VE        VEW  +G ++   + + T    G V  L I +   
Sbjct: 2972 LKEVVEGSRTDLE--VEVSGKPKPVVEWLKDG-ELVKPSSLMTLETEGQVHTLTIMNTTL 3028

Query: 1111 EDSGVYTVVARNAAGEAQLSASMTVE 1136
            +D G YT +A+N  GE   +A + VE
Sbjct: 3029 DDEGEYTCIAKNKVGEVSCTAELLVE 3054



 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 51/194 (26%), Positives = 82/194 (42%), Gaps = 6/194 (3%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            KVEW  N+  ++SG RF   ++     L +     +D G   C A N+ G   +    IV
Sbjct: 2867 KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSMASLIV 2926

Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729
              K S     Q E  +  + Q     ++Q     +      P F   ++   V E     
Sbjct: 2927 RDKPS----EQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRLELKEVVEGSRTD 2982

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
             E  +   G PK  VEWL++G  ++ S+ +T   +     L +     +D G YTC A N
Sbjct: 2983 LEVEV--SGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKN 3040

Query: 1790 ELGEAVTSSTLFVQ 1803
            ++GE   ++ L V+
Sbjct: 3041 KVGEVSCTAELLVE 3054



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 8/209 (3%)

Query: 1862 AHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKA 1921
            A +E  I   P+P  +VEW  N  +++SG R+   +D     L +     +D GE  C A
Sbjct: 2854 AIFEVEITGKPEP--KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTA 2911

Query: 1922 INNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFG 1981
             N+ G   S   L V+ K S     Q E  ++ +     + +++   + +      P+F 
Sbjct: 2912 TNSAGTVTSMASLIVRDKPS----EQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFL 2967

Query: 1982 KPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILY 2041
            + ++  EV EG    LE  ++    P   VEW  +G  V+         +     L I+ 
Sbjct: 2968 QRLELKEVVEGSRTDLEVEVS--GKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMN 3025

Query: 2042 AYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
               +D G Y C A N VGE   T+ + V+
Sbjct: 3026 TTLDDEGEYTCIAKNKVGEVSCTAELLVE 3054



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 67/242 (27%), Positives = 107/242 (44%), Gaps = 19/242 (7%)

Query: 3719 VEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            VE  G P  +++W  N     +G R    +D     L +      D GE  C ATN  G+
Sbjct: 2858 VEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGT 2917

Query: 3779 ATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE-EPIVSTPPKFITQIK 3837
             T+ A +    K     +++L     G++  E++       P E EP     PKF+ +++
Sbjct: 2918 VTSMASLIVRDKPS--EQTELYIKPVGQEPVEMQ----FQVPFETEPTDEAGPKFLQRLE 2971

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSGHRYRTVYDMGFV-SLDILYVY 3895
                E  EG R +  VE    PK  +EW ++G+L+ PS     T+   G V +L I+   
Sbjct: 2972 --LKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSS--LMTLETEGQVHTLTIMNTT 3027

Query: 3896 AEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTS 3955
             +D GEY C A N  GE      +SC     +    + P+ + +  +L  ME  + K+ +
Sbjct: 3028 LDDEGEYTCIAKNKVGE------VSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEA 3081

Query: 3956 EV 3957
             V
Sbjct: 3082 RV 3083



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 64/238 (26%), Positives = 109/238 (45%), Gaps = 17/238 (7%)

Query: 2797 VEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGS 2856
            VE +  P  K+EW  N+  + SG R++   D +  +L +  +  +D G   C ATNS G+
Sbjct: 2858 VEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGT 2917

Query: 2857 ATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIP 2916
             T+  SL       I  D    Q +  ++ V Q E   +          T+   P+++  
Sbjct: 2918 VTSMASL-------IVRDKPSEQTELYIKPVGQ-EPVEMQFQVPFETEPTDEAGPKFLQR 2969

Query: 2917 IAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDV 2976
            +  + ++VEG    LE +V  K  P   +EW  +G++++  S   L ++    TL +++ 
Sbjct: 2970 LELK-EVVEGSRTDLEVEVSGKPKP--VVEWLKDGELVKPSSLMTLETEGQVHTLTIMNT 3026

Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRK 3034
               D G YTC A NK GE      V CT++  + E  + P+       +Q +E  + K
Sbjct: 3027 TLDDEGEYTCIAKNKVGE------VSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAK 3078



 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 54/202 (26%), Positives = 86/202 (42%), Gaps = 9/202 (4%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595
            G P  + EW  N V ++ G RF    D    TL +     +D G   C A N AG     
Sbjct: 2862 GKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSM 2921

Query: 2596 XXXXXXXX-XXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKL 2654
                         +  ++P   E ++++     +VP     T  +  P F   L+   ++
Sbjct: 2922 ASLIVRDKPSEQTELYIKPVGQEPVEMQF----QVPFETEPTD-EAGPKFLQRLE-LKEV 2975

Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714
            VEG    LE +V  +  P   +EW K+G  +   + +    +  + TL+I +   DD G 
Sbjct: 2976 VEGSRTDLEVEVSGKPKP--VVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGE 3033

Query: 2715 YTCKATNLLGEAVSTASIKIED 2736
            YTC A N +GE   TA + +E+
Sbjct: 3034 YTCIAKNKVGEVSCTAELLVEE 3055



 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 64/222 (28%), Positives = 92/222 (41%), Gaps = 38/222 (17%)

Query: 3692 PNPPRFTVEI-KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750
            P PP FT E  K   D  EGG + F+  V   G P   ++W  +  P +  S  H     
Sbjct: 3249 PVPPHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSN 3306

Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810
               +L I  +   D+G YTC ATN+ G A  T  I         +E+  P+G + + I  
Sbjct: 3307 DTYSLTIRGVGPDDSGAYTCTATNECGMAKRTYNID--------IEASEPKGSTPQFIDL 3358

Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK 3870
            ++                 P  +T+ ++ T E        C V  K  P+  IEW++NG 
Sbjct: 3359 MQ-----------------PVEVTEGQTATFE--------CTV--KGYPRPSIEWFKNGL 3391

Query: 3871 LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
             L    R  + Y+    SL I     +D G Y C A N FG+
Sbjct: 3392 PLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGK 3433



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 107/510 (20%), Positives = 193/510 (37%), Gaps = 37/510 (7%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E T  P+    + D +SI  G   +   +    G     V+W  D   +     +   
Sbjct: 2582 INEKTIPPKITQRLHD-LSIDAGKTVNLTVKF--FGTPEPLVKWFMDDEEITNEDGVDIE 2638

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
             +    +L +  V   D G Y C  +N  G+ +T++ +T+   K   A  +    +  + 
Sbjct: 2639 TSHCTSSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKGVKIEPAIQEPVEAVLSLP 2698

Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081
              E  S   K T+++V      R    + G        + +++ +   +  +    E+ F
Sbjct: 2699 RGEAPSFTKKITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQTK---RRCIRERSEFLF 2755

Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
            N K ++  +         Y       + A  S V+  +   +  E +  A +TV    + 
Sbjct: 2756 NNKLLSDVSFRVGKEQGKYFIPGHKLILAISSPVFYAMFYGSMAEQK--AEITVADSDAD 2813

Query: 1142 DTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRL 1201
                + R  Y     I E   +  +Y  ++       ++ P      +++ K I     +
Sbjct: 2814 SFMELLRYAYFDEATINEENVLGVLYLAKK-------YILPF-----LADNKAIF---EV 2858

Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261
            E  G P  +VEW  N   +  G RF+   D     L +  +   D GE    A N  G+ 
Sbjct: 2859 EITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTV 2918

Query: 1262 HTSAIVRVIERSDIVTDTQNEQAIEQIQLL-EDAARRTKQV--REDITVMQAPQFSRALH 1318
             + A       S IV D  +EQ    I+ + ++      QV    + T    P+F + L 
Sbjct: 2919 TSMA-------SLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDEAGPKFLQRLE 2971

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
              E VEG+   LE  +   G     VEW  +G+ +K         E     L +++   +
Sbjct: 2972 LKEVVEGSRTDLEVEVS--GKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLD 3029

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
            D G YTC A N++GE   SC   ++ ++ +
Sbjct: 3030 DEGEYTCIAKNKVGE--VSCTAELLVEEGM 3057



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 109/498 (21%), Positives = 182/498 (36%), Gaps = 46/498 (9%)

Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748
            +EK  PP+ T  + D + +  G  V+    V+  G P   + WF +         V    
Sbjct: 2583 NEKTIPPKITQRLHD-LSIDAGKTVNLT--VKFFGTPEPLVKWFMDDEEITNEDGVDIET 2639

Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
                 +L +  +   D G Y C   N  G  +T +KIT    + + +E  + + +  E +
Sbjct: 2640 SHCTSSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITV---KGVKIEPAIQEPV--EAV 2694

Query: 3809 KELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEP-KEDPKLRIE-WY 3866
              L RG               P F  +I    V E++ VR E  V     +P    + W 
Sbjct: 2695 LSLPRGEA-------------PSFTKKITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQ 2741

Query: 3867 RNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPD 3926
               + +    R   +++   +S D+ +   ++ G+Y              + +       
Sbjct: 2742 TKRRCIRE--RSEFLFNNKLLS-DVSFRVGKEQGKYFIPGHKLILA--ISSPVFYAMFYG 2796

Query: 3927 IILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLV 3986
             + + +    +  S+A + ME     Y  E  + E+++  V        +  +    ++ 
Sbjct: 2797 SMAEQKAEITVADSDADSFMELLRYAYFDEATINEENVLGVLYLAKKYILPFLADNKAIF 2856

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEY 4046
            E+E T         G P  KVEW  N   +   +RF P  D     +       +D GE 
Sbjct: 2857 EVEIT---------GKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEI 2907

Query: 4047 LCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESK 4106
             C ATN  G   + A +    KP      Q   ++K + +   +E  +QV  E    E  
Sbjct: 2908 KCTATNSAGTVTSMASLIVRDKPS----EQTELYIKPVGQ-EPVEMQFQVPFET---EPT 2959

Query: 4107 ARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH 4166
                P F+   +   V EG        V+G PKP V WL +G  +   S   L  +G  H
Sbjct: 2960 DEAGPKFLQRLELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVH 3019

Query: 4167 -FDIPKTRQYDTGKIEVI 4183
               I  T   D G+   I
Sbjct: 3020 TLTIMNTTLDDEGEYTCI 3037



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 4/89 (4%)

Query: 69   PSPPIF-EQIFK-NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
            P PP F E+  K    F +GG+  FE  + G P P V W + +AP+ E + Y +  +  T
Sbjct: 3249 PVPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHYHLHRSNDT 3308

Query: 127  GDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
               SL I+ +GP D G YTCTA N+ G A
Sbjct: 3309 --YSLTIRGVGPDDSGAYTCTATNECGMA 3335



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 2/97 (2%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            ++ P F KP+K+ EV EG P  L+  +T +  P   V+W  +G P++ G  FKT      
Sbjct: 2030 IQPPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
              L I  A  ED G Y C+A N  G A T + + V++
Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVES 2124



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 70/265 (26%), Positives = 112/265 (42%), Gaps = 43/265 (16%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F  PLK     EG     + +I  +  P   ++WLK+G+ ++    F +        
Sbjct: 2032 PPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTYF 2089

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV-------TPRATIERTSQHPETLQYIQ 748
            L +   +++D G Y C AV+  G A T+A + V        P    ++  Q  +T+   Q
Sbjct: 2090 LIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAIGQ 2149

Query: 749  Q-------LE-----DYS----KYQHQESIEE--------QTSQRPQFIRP-----LQDL 779
            +       L+     D+     K  H + I E        QT+  P+ I P     L+D+
Sbjct: 2150 EPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSALRDI 2209

Query: 780  GELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA-SSRITSIFNFGYV-SLNIMHLRA 837
             E+ EG        +T    P   V+W+KDG+P++    R   +   G V +L I   R 
Sbjct: 2210 -EVNEGNTVTLRIHVT--GSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARG 2266

Query: 838  EDAGSYTVRAVNKLGEAISTASIRV 862
             D G Y  +A N  GE  S+ ++ V
Sbjct: 2267 SDTGKYLCKAYNSAGEVTSSCNVDV 2291



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 65/267 (24%), Positives = 101/267 (37%), Gaps = 28/267 (10%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P F +      V+EG+P  L+ +    P   + W KDG P+ P    +    G    L I
Sbjct: 2033 PFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLII 2092

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRAR-LYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXX 609
            P A   D   Y+C A N AG  +T A  L            +   + + TK         
Sbjct: 2093 PEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAIGQEPP 2152

Query: 610  XXXXYL--------RHVERARPYIPP-GEED--------RVYPPP---QFIVPLKSVTAM 649
                 L        + VE   P+     EED           P P   +F   L+ +   
Sbjct: 2153 AVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSALRDIEVN 2212

Query: 650  EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEA-SSRFTSIFRFGYI-SLDMLSLNIQDSG 707
            EG  +    RI   G P  +++W K+G+ +     R   +   G + +L +      D+G
Sbjct: 2213 EGNTV--TLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTG 2270

Query: 708  EYTCRAVSATGVAETKA---VLHVTPR 731
            +Y C+A ++ G   +     VLHV P+
Sbjct: 2271 KYLCKAYNSAGEVTSSCNVDVLHVAPK 2297



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 40/117 (34%), Positives = 56/117 (47%), Gaps = 1/117 (0%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            +A+ +AI F  +I GKP P V+W K D LI+    F+       YTL +  +  +DEG+ 
Sbjct: 2849 LADNKAI-FEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEI 2907

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            KC A NSAG VT  A L V           + P+    V       F+T+ T +  P
Sbjct: 2908 KCTATNSAGTVTSMASLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDEAGP 2964



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 60/215 (27%), Positives = 89/215 (41%), Gaps = 16/215 (7%)

Query: 788  AHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
            A FE ++T   +P  +VEW K+   I +  R     +    +L +   R +D G     A
Sbjct: 2854 AIFEVEITGKPEP--KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTA 2911

Query: 848  VNKLGEAISTASIRVAARSTVTADLGI-PEQRRYIEKTXXXXXXXXXXXXXXXXXVPEST 906
             N  G   S AS+ V  + +   +L I P  +  +E                    P+  
Sbjct: 2912 TNSAGTVTSMASLIVRDKPSEQTELYIKPVGQEPVEMQFQVPFETEPTDEAG----PKFL 2967

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            Q+ E K        + EG     E  +E  G     VEWLKDG  V+ SS +T       
Sbjct: 2968 QRLELK-------EVVEGSRTDLE--VEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQV 3018

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              LTI + T+ D G YTC A N +G+ + +A L +
Sbjct: 3019 HTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLV 3053



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            IE  EPK S P+F+ +L     V EG+TA FEC V+    P+  IE++ NG  L+   R 
Sbjct: 3343 IEASEPKGSTPQFI-DLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERI 3399

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              T++    SL I  C  +D G Y   A N+ G  + A  + V
Sbjct: 3400 ASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 33/83 (39%), Positives = 44/83 (53%), Gaps = 2/83 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PPQFIV   S+  MEG    FE R+   G P  ++EWL++G+ I+   RF   F      
Sbjct: 3059 PPQFIVKPSSLQIMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSV 3116

Query: 696  LDMLSLNIQDSGEYTCRAVSATG 718
            L ++   + D GEYTC A S  G
Sbjct: 3117 LTIIDAKLNDEGEYTCVATSKAG 3139



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 61/216 (28%), Positives = 86/216 (39%), Gaps = 36/216 (16%)

Query: 2376 PVFTQPLQNID-NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            P FT+    I  + +EG    F+  +   G P   VEW ++E  I +SS           
Sbjct: 3252 PHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDTY 3309

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494
            S+TI  V  +D G Y C A+N  G               I +E   P+G           
Sbjct: 3310 SLTIRGVGPDDSGAYTCTATNECG--------MAKRTYNIDIEASEPKG----------- 3350

Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
                         P F  ++  P E+ EGQ A +E  V     PS+  EW+ NG+ LK  
Sbjct: 3351 -----------STPQFIDLMQ-PVEVTEGQTATFECTVKGYPRPSI--EWFKNGLPLKEN 3396

Query: 2555 SRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             R  +T++    +L IN    +D G Y C A N  G
Sbjct: 3397 ERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFG 3432



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 33/98 (33%), Positives = 55/98 (56%), Gaps = 3/98 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+FI  L  P +++EGQ+A +EC ++ YP P+  +EW+ NG  L+   R  ++ +   ++
Sbjct: 3353 PQFI-DLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSS 3409

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            L I     +D G Y C A N+ G+A  +  L V   +S
Sbjct: 3410 LTINQCTIDDEGNYKCVARNSFGKASCATELLVDEADS 3447



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 61/198 (30%), Positives = 86/198 (43%), Gaps = 15/198 (7%)

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
            G    +VEW  N   I++G RF P  +     L L     +D G   C ATN  G  VTS
Sbjct: 2862 GKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAG-TVTS 2920

Query: 1398 CALRVIAKKDLILESQH--PSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIEN 1455
             A  ++  K       +  P G E ++         +T+  DE+    P+F+ R   ++ 
Sbjct: 2921 MASLIVRDKPSEQTELYIKPVGQEPVEMQFQVP--FETEPTDEA---GPKFLQR-LELKE 2974

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV-ALDIIDLIAEDS 1514
            V+EG     E  +E        VEW K+G+ V        +   G V  L I++   +D 
Sbjct: 2975 VVEGSRTDLE--VEVSGKPKPVVEWLKDGELVK-PSSLMTLETEGQVHTLTIMNTTLDDE 3031

Query: 1515 GIYTCRAVNLVGTDEVSC 1532
            G YTC A N VG  EVSC
Sbjct: 3032 GEYTCIAKNKVG--EVSC 3047



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 61/233 (26%), Positives = 101/233 (43%), Gaps = 41/233 (17%)

Query: 2104 QPGQRPV-FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            + G RP  F+   +SL+ + EG  A FE RV  +  P   ++W  +G+ I+ G R++   
Sbjct: 3054 EEGMRPPQFIVKPSSLQ-IMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEF 3110

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQ 2222
            +     L I+     D G Y C AT+K G+  ++C++++     ++     P  + KI  
Sbjct: 3111 EKDRSVLTIIDAKLNDEGEYTCVATSKAGK--DSCSVELLVDEAVV----PPEFVRKI-- 3162

Query: 2223 LEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
                   + IE+ E +I+  RF   + GT                    P   + +Y + 
Sbjct: 3163 -------SNIELTEGEIA--RFDVRITGT--------------------PAPEVTWYKDE 3193

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
              ++   RF I  D    SL I+ C   D G YS KA N  G  +    +T+T
Sbjct: 3194 VPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTIT 3246



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 56/220 (25%), Positives = 96/220 (43%), Gaps = 38/220 (17%)

Query: 2241 PPRFVTEL-RGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY 2299
            PP F  E  +  T   EG    FE  V     P+  +E++ +   +  ++ +H+      
Sbjct: 3251 PPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDT 3308

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
             SL I+   P+D+G Y+  A N  G      ++                      ++E++
Sbjct: 3309 YSLTIRGVGPDDSGAYTCTATNECGMAKRTYNI----------------------DIEAS 3346

Query: 2360 EPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI 2419
            EP  +   P+ +   +PV          + EGQTA F+C +   G P   +EWF+N   +
Sbjct: 3347 EP--KGSTPQFIDLMQPV---------EVTEGQTATFECTV--KGYPRPSIEWFKNGLPL 3393

Query: 2420 EDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +++ RI  T++    S+TI+    +DEG Y C A N  G+
Sbjct: 3394 KENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGK 3433



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 52/199 (26%), Positives = 79/199 (39%), Gaps = 4/199 (2%)

Query: 2665 QVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724
            +VE    P  K+EW KN V + +G R +   D  + TL++   R DD G   C ATN  G
Sbjct: 2857 EVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAG 2916

Query: 2725 EAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIV 2784
               S AS+ + D+     E L+   + +   +                   F+  L    
Sbjct: 2917 TVTSMASLIVRDKPSEQTE-LYIKPVGQ-EPVEMQFQVPFETEPTDEAGPKFLQRLELKE 2974

Query: 2785 CKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSG 2844
              EG     E  VE S  P   +EW  + + +   +      +    +L I +T  +D G
Sbjct: 2975 VVEGSRTDLE--VEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEG 3032

Query: 2845 IYTCKATNSKGSATTSGSL 2863
             YTC A N  G  + +  L
Sbjct: 3033 EYTCIAKNKVGEVSCTAEL 3051



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 103/457 (22%), Positives = 176/457 (38%), Gaps = 76/457 (16%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G+P   V W ++ VP++ + R+    +     + +K  N EDS  +T    N+ G A+  
Sbjct: 3772 GEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVTIKDANKEDS-VFT-NITNDFGTAIRR 3829

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857
             ++ V            ES + K+Q        +R ED    VN       +   P +++
Sbjct: 3830 FSIDV------------ESVMPKLQGF-----VKRDEDFPQFVN------VEGVSPFEVT 3866

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHR-YRTSNDFGFAALDILT-VYGEDS 1914
                   + R+  +P+P+  V W+ +G  V+ + H  Y   +D     +   T +Y   +
Sbjct: 3867 SEGDIKLQTRVTGFPEPD--VSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLY---A 3921

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G Y C A N  G       + +++ E          A E I + +D+   +       F+
Sbjct: 3922 GTYKCVATNRRGTNSRDFEVTIETGE----------AAEHITFQQDEETVRA-----QFI 3966

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
             + P    P    E+TE   V L+  +  +  P   ++W+ +GR +      K T D   
Sbjct: 3967 EKGPYAPVPF---EITEEGDVKLQVRICGI--PFPEIDWFKDGRHLSPDDHIKITSDDDL 4021

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094
              + I     +DTG Y C   N  G+A  T  V +        + +   R  + +  E  
Sbjct: 4022 YTVLIRQPTIKDTGKYKCIIKNIAGKATRTFDVDI--------EAVKPSRHVRGELSEHL 4073

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
              PK I+          +T ++      +GD      ++    D    + W  +G+ I  
Sbjct: 4074 ILPKFID----------VTEVSPYRVSYDGDFT-LTVKLSGSGD----VQWMKDGEVIED 4118

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
              RY    D     L IL    +D GTY C  TNK G
Sbjct: 4119 SKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAG 4155



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 73/317 (23%), Positives = 122/317 (38%), Gaps = 36/317 (11%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            PK       S  +   D  F + +  +    V W K+G+ + +S ++ I    +   L +
Sbjct: 4076 PKFIDVTEVSPYRVSYDGDFTLTVKLSGSGDVQWMKDGEVIEDSKRYVIRQDDDLHMLTI 4135

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
                + D G Y  +  N  G    S  + +E      ++     Y          E  E+
Sbjct: 4136 LGATEDDLGTYKCVVTNKAGFDTRSFDIGLED-----LRPHTFAY----------EPSEL 4180

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
                     V   Q  D  + K+T    RV G+P P V W  ND  +    +  +L+ E 
Sbjct: 4181 VAPYYLEDGVTAFQMTDAGDVKLT---VRVRGKPKPTVKWTKNDEPVVPSSHFSVLM-ED 4236

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE----QVV----APKFVER- 496
               +L+I   + +D GV   +A N+ G    +  +++   E    +VV    AP+F++  
Sbjct: 4237 DVFSLLIRKPSKTDKGVYKVIATNEGGINTKRFNVDIEWDETTTTRVVDDREAPRFLDDG 4296

Query: 497  FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
             S+     G  V L  +  G P P +TW +D   I P+    + +D            A 
Sbjct: 4297 ISSYEFTSGGDVKLTVKVTGRPYPTVTWSRDDKDIKPDDTFHMFSD--------DENPAE 4348

Query: 557  DAAWYQCTAQNVAGSTA 573
            +   Y+CT  N AG  A
Sbjct: 4349 NQGSYKCTIANEAGVRA 4365



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 86/346 (24%), Positives = 143/346 (41%), Gaps = 52/346 (15%)

Query: 3403 SMVRRKDTSVEEEKG--KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
            +++++K ++ E   G  + P F  PL + E ++EG+    + ++T   + N+K  W  +G
Sbjct: 2014 NVLQKKRSTAEIMMGDIQPPFFQKPLKDKE-VKEGKPFKLDVKITALPEANVK--WLKDG 2070

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIIL 3520
            + LK G  F+T        L I     ED G Y C A NN G A T A + V+       
Sbjct: 2071 EPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSE 2130

Query: 3521 ESQLPKGMEGTIDKIA----------ALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILS 3570
                P+ ME +   IA           L+G +G  D    E +  +P E       + + 
Sbjct: 2131 PEDEPQQMEQSTKTIAIGQEPPAVTLTLDGKAG-FDFQAVELKIPHPDEIAEEDLRIDVE 2189

Query: 3571 ENSS------AHFECRL--IPVNDS---SMRVEWFHNGKP----LLTGSRVKTINDFGFV 3615
            + ++        F+  L  I VN+    ++R+    + KP       G  V  +    F 
Sbjct: 2190 QTAALPKPIPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFE 2249

Query: 3616 ILEIGGVYQ--------RDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKS 3667
            +  +G VY          D G Y CKA N  GE T SC + V     + + P+ P  F+ 
Sbjct: 2250 VGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDV-----LHVAPKEPPKFER 2304

Query: 3668 GTESIQKLEETLHKREEITIEDEKPNPPRF------TVEIKDNIDV 3707
              + I  + E    R ++ +    P P  F       V+ +D++D+
Sbjct: 2305 NLKDI-TIAEGCSTRFDVQVTG-SPEPKVFWYHNGKLVQPRDHVDI 2348



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 3/96 (3%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            EPPKF   ++D+T + EG S  F+ ++     P+ KV W++NGK +         HD   
Sbjct: 2298 EPPKFERNLKDIT-IAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDDEH 2354

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
              L +++C  + SG+Y CVA N++G+  + A L  T
Sbjct: 2355 SSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHIT 2390



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 63/230 (27%), Positives = 96/230 (41%), Gaps = 16/230 (6%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P+ KVEW  N   +  G R+    D  +  L +     ++ GE +C ATN  G  ++ A+
Sbjct: 2864 PEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSMAS 2923

Query: 3372 LKCTSKENLILDSQL-PRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIE 3430
            L    K +   +  + P G E        +E       +T   +E G  P F   L  ++
Sbjct: 2924 LIVRDKPSEQTELYIKPVGQE-------PVEMQFQVPFETEPTDEAG--PKFLQRL-ELK 2973

Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDS 3490
             + EG     E  +  +  P   VEW  +G+ +K  S      +     L I  T  +D 
Sbjct: 2974 EVVEGSRTDLEVEV--SGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDE 3031

Query: 3491 GEYLCRAYNNYGEAVTTASMKV-QGKR--NIILESQLPKGMEGTIDKIAA 3537
            GEY C A N  GE   TA + V +G R    I++    + MEG + K  A
Sbjct: 3032 GEYTCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEA 3081



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 14/145 (9%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            PQF   ++  EVTEG     E T+     P+  +EW+ NG P+++  R  +TY+    +L
Sbjct: 3353 PQFIDLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSL 3410

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK-------SGLYLDTLDEQRLKKIQE 2090
             I     +D G Y C A N+ G+A   + + VD         SG  ++   ++ LK+  E
Sbjct: 3411 TINQCTIDDEGNYKCVARNSFGKASCATELLVDEADSPEDQVSGKIMNF--DRELKRDFE 3468

Query: 2091 LEKYERPK-PIEEEQP--GQRPVFL 2112
             E    PK  +E + P  GQR + L
Sbjct: 3469 AEDLFNPKVQVEVQMPPEGQREITL 3493



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 64/257 (24%), Positives = 105/257 (40%), Gaps = 38/257 (14%)

Query: 1154 TRHIEESKFVEPMYQ----IEEI---SKSKPVFVQPLSNPP-PVSEGKNIHLECRLEPMG 1205
            T+ +++ K +EP       IE++    K +P+F++     P  V+E  +I +  ++   G
Sbjct: 4818 TKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVT--G 4875

Query: 1206 DPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             P   VEW  + R V   S  K   +    +L I   T +D G YTV+  N +GS   + 
Sbjct: 4876 KPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTF 4935

Query: 1266 IVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEG 1325
             V+V    D  T             L +   R K + +D  V             E+ E 
Sbjct: 4936 DVKV---EDTTTS------------LFEGTVRPKFIEDDSFV-----------PFESTEE 4969

Query: 1326 TNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTC 1385
             NV L  ++   G     V W  + KP+      R  ++ D   L +    P DSG Y C
Sbjct: 4970 GNVRLSVKI--TGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKC 5027

Query: 1386 QATNQLGEAVTSCALRV 1402
              TN  G++  + ++ +
Sbjct: 5028 TLTNDAGKSTRTFSVEI 5044



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 8/120 (6%)

Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367
            M+ PQF     +++ +EG     E R+   G     VEW  +G+PIK G RF+  +E D 
Sbjct: 3057 MRPPQFIVKPSSLQIMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRRFQIEFEKDR 3114

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
              L ++     D G YTC AT++ G+   SC++ ++  + ++     P  + KI  +E T
Sbjct: 3115 SVLTIIDAKLNDEGEYTCVATSKAGK--DSCSVELLVDEAVV----PPEFVRKISNIELT 3168



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 55/174 (31%), Positives = 75/174 (43%), Gaps = 15/174 (8%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S +V+ L  EA    PPEF    S++ L+E   A F+ R+      +  V W+ +  P+ 
Sbjct: 3142 SCSVELLVDEAVV--PPEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIE 3197

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL 3661
             G R +  +D     L I      D G Y+CKATN  G+A  SC     G   I   P +
Sbjct: 3198 DGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA--SC----YGELTITFIP-V 3250

Query: 3662 PSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVE-IKDNIDVPEGGPVH 3714
            P HF   TE   K+     +  +IT E      PR  VE  KD   + E    H
Sbjct: 3251 PPHF---TEEAPKIPTDFEEGGDITFEATVSGRPRPDVEWHKDEAPISESSHYH 3301



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            V  P+F + I N E+TEG     +  +T    P   V WY +  P++ G RF+   D   
Sbjct: 3153 VVPPEFVRKISNIELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIYSDDDK 3210

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEA 2061
             +L I      DTG+Y CKATN  G+A
Sbjct: 3211 HSLVIRDCALSDTGSYSCKATNEAGQA 3237



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 67/224 (29%), Positives = 108/224 (48%), Gaps = 43/224 (19%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            PK  PP+F   L+  T + EG +  F+ QV    +P  ++ +YHNGK +Q   R H+   
Sbjct: 2296 PK-EPPKFERNLKDIT-IAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQP--RDHV--- 2346

Query: 2297 FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIREL 2356
                  DI H   +D  E+S      L HC     + ++ K + ++E++       + ++
Sbjct: 2347 ------DIVH---DD--EHSSLI---LMHCP----LDLSGKYTCVAENE-------VGQV 2381

Query: 2357 ESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNE 2416
            +SA    R  I E   +  P F + L N+ +I  G T   +CR+   G P  +V WF+++
Sbjct: 2382 QSAA---RLHITELAIQ--PKFAERLTNV-SISSGDTIVLECRV--TGKPRPQVAWFKDD 2433

Query: 2417 KLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            K I   SR + +T       +TI  V  +DEG Y C A+N  G+
Sbjct: 2434 KEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQ 2477



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 3/98 (3%)

Query: 61   ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            I A  P + S P F  + +     +G  A FE  ++G P P + W +   PL E  + + 
Sbjct: 3343 IEASEP-KGSTPQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIAS 3401

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
             Y       SL I Q    DEG Y C ARN +G+A C+
Sbjct: 3402 TYEGALS--SLTINQCTIDDEGNYKCVARNSFGKASCA 3437



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 17/169 (10%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            +I   + K + P+F +++   ++V EG    F+C V+  G P   I+WF NG P     R
Sbjct: 3342 DIEASEPKGSTPQF-IDLMQPVEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENER 3398

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
            + +  +    +L I+     D G Y C A N +G A+   ++       +V E+  P+  
Sbjct: 3399 IASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATEL-------LVDEADSPEDQ 3451

Query: 3804 SGEKIKELERGRISD-------APKEEPIVSTPPKFITQIKSHTVEESE 3845
               KI   +R    D        PK +  V  PP+   +I   + E+++
Sbjct: 3452 VSGKIMNFDRELKRDFEAEDLFNPKVQVEVQMPPEGQREITLESTEQTK 3500



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            ++ EGQ    E  V+    P+  IEWFKNG+ L    R+ ST++  L +L+IN    DD 
Sbjct: 3363 EVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDE 3420

Query: 2713 GIYTCKATNLLGEAVSTASIKIED 2736
            G Y C A N  G+A     + +++
Sbjct: 3421 GNYKCVARNSFGKASCATELLVDE 3444



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 3/91 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+F+ +P S++ ++EG+   FE ++  +     +VEW ++G+P+  G RF+   +     
Sbjct: 3060 PQFIVKPSSLQ-IMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEFEKDRSV 3116

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L IID    D G YTC A +  G D  S  L
Sbjct: 3117 LTIIDAKLNDEGEYTCVATSKAGKDSCSVEL 3147



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 3/100 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E+   PEF   I + I + EG  A F+ R+   G     V W KD  P+E   R   +
Sbjct: 3149 VDEAVVPPEFVRKISN-IELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIY 3205

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +    +L I+   + D G Y+C+A N  GQA+    LTI
Sbjct: 3206 SDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTI 3245



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 3275 STPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334
            S P    P+FI  +Q V ++ EGQ+A FE  +     P   +EWF NG  L    R  + 
Sbjct: 3346 SEPKGSTPQFIDLMQPV-EVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIAST 3402

Query: 3335 HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            ++  +  L I  C  ++ G Y+CVA N  G+ S    L
Sbjct: 3403 YEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATEL 3440



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 57/221 (25%), Positives = 85/221 (38%), Gaps = 31/221 (14%)

Query: 1984 IKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAY 2043
            +K  EVTE   + +   +T    P   VEW  + RPV      K T +    +L I    
Sbjct: 4856 VKPFEVTEEGDIKMTVKVT--GKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPT 4913

Query: 2044 AEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDEQRLKKIQELEKYERPKPIEE 2102
              D G Y  K TN VG    T  VKV D  + L+  T+               RPK IE+
Sbjct: 4914 KSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFEGTV---------------RPKFIED 4958

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            +          +    E+ +EG   +    V+    P   + W  + + +      R  H
Sbjct: 4959 D----------SFVPFESTEEG---NVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDH 5005

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                  L I      DSG+Y C  TN  G++  T ++++ G
Sbjct: 5006 QDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEG 5046



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 3/100 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E  + P+F       + I EG  A FEAR+  +      VEWL+DGRP++   R    
Sbjct: 3053 VEEGMRPPQFIVK-PSSLQIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIE 3109

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            F      LTI    ++D G YTC A +  G+ + S  L +
Sbjct: 3110 FEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLV 3149



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 2/97 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   M+ + V E Q A FE  +   G P+  +EW +NG+P++ + R+ + ++    +L
Sbjct: 3353 PQFIDLMQPVEVTEGQTATFECTV--KGYPRPSIEWFKNGLPLKENERIASTYEGALSSL 3410

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
             +     +D G Y C A N  G+A  ++ L V    S
Sbjct: 3411 TINQCTIDDEGNYKCVARNSFGKASCATELLVDEADS 3447



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 79/343 (23%), Positives = 140/343 (40%), Gaps = 50/343 (14%)

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS-------LQLESQHESALQ--- 1819
            L ++  +P D+G+Y C   ++ G +  +  + + S           ++E  HE  L    
Sbjct: 4755 LTIREPSPNDTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEET 4814

Query: 1820 ----KIQQLE---DSSRYQRR--EDVEVAVNQAPRFI-TQLNGPTKLSEGQSAHYECRIE 1869
                KI Q E   + +R ++   EDV     Q P FI T    P +++E        ++ 
Sbjct: 4815 MSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVT 4874

Query: 1870 PYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929
              P P+  VEW  + + + S    + + +    +L I      D G YT K  N++G   
Sbjct: 4875 GKPKPS--VEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGT 4932

Query: 1930 SSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEV 1989
             +  + V+   +    S  E  +             + ++DDSFV        P ++ E 
Sbjct: 4933 RTFDVKVEDTTT----SLFEGTVR-----------PKFIEDDSFV--------PFESTE- 4968

Query: 1990 TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGT 2049
             EG+ V L   +T    P   V W  + +PV +    +  +      L I  A   D+G+
Sbjct: 4969 -EGN-VRLSVKIT--GKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGS 5024

Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092
            Y C  TN  G++  T SV+++ ++        E+  K ++E E
Sbjct: 5025 YKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEE 5067



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 15/140 (10%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            Q P F  P+KD  V E +    + ++  +  P+  V+WL++G P++  +   T       
Sbjct: 2031 QPPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTY 2088

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L +   + ED G Y C A+N  G A T + + V+S A    E + E      QQ+E S+
Sbjct: 2089 FLIIPEADVEDEGRYRCEAVNNAGRASTEADILVES-ADEGSEPEDEP-----QQMEQST 2142

Query: 1829 RYQRREDVEVAVNQAPRFIT 1848
            +        +A+ Q P  +T
Sbjct: 2143 K-------TIAIGQEPPAVT 2155



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 49/176 (27%), Positives = 72/176 (40%), Gaps = 8/176 (4%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV-VLEILGTKTT 3116
            V IS G     E  +  TG     + WF + K I    R       G V VL I G    
Sbjct: 2405 VSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPD 2462

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D G+Y C ATN  GQ +   +L      +G  P F   + +I+ + +G    FE  VV  
Sbjct: 2463 DEGSYKCIATNPAGQDDTVAELTVA--KRGNPPFFVKELVDID-VTEGGHERFE--VVVD 2517

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              P  +I+WY N   +R   +           L +   +  ++G+  C+A N  G+
Sbjct: 2518 GYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQ 2573



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 4/121 (3%)

Query: 3039 QPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR 3098
            +  +  G  P+F  + +  V+++EGQ A +E ++   G     IEWF NG  ++ + RI 
Sbjct: 3344 EASEPKGSTPQFIDLMQP-VEVTEGQTATFECTV--KGYPRPSIEWFKNGLPLKENERIA 3400

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            + Y   +  L I      D G Y C A N +G+A  + +L  VD++   + + +  I N 
Sbjct: 3401 STYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATEL-LVDEADSPEDQVSGKIMNF 3459

Query: 3159 E 3159
            +
Sbjct: 3460 D 3460



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 65/256 (25%), Positives = 108/256 (42%), Gaps = 35/256 (13%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F   +K   V+E +  + + ++     P+  ++W ++G+ L  G  ++T        
Sbjct: 2032 PPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTYF 2089

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRS-------- 3940
            L I     ED G Y C AVN+ G   T+A I  +   +       P+ M++S        
Sbjct: 2090 LIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAIGQ 2149

Query: 3941 --EALT---------QMEATIKKYTSEVYLTEDDL-YDVDKKQ--PPRFVTQIQSQTSLV 3986
               A+T           +A   K      + E+DL  DV++    P     + +S    +
Sbjct: 2150 EPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSALRDI 2209

Query: 3987 EM-ETTKFECQLAPVGDPNMKVEWFFNGKPL--LHKNRFTPIYDFGYVAMNFGWVYPE-- 4041
            E+ E      ++   G P  +V+WF +GKP+  L   RF    + G V   +  V  E  
Sbjct: 2210 EVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRF----EVGCVGEVYTLVIKEAR 2265

Query: 4042 --DSGEYLCRATNLYG 4055
              D+G+YLC+A N  G
Sbjct: 2266 GSDTGKYLCKAYNSAG 2281



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 4/95 (4%)

Query: 2100 IEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158
            IE  +P G  P F+  +  +E + EG  A FEC V+    P  +I+WF NG  ++   R 
Sbjct: 3343 IEASEPKGSTPQFIDLMQPVE-VTEGQTATFECTVKGY--PRPSIEWFKNGLPLKENERI 3399

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
             +T++    +L I     +D G Y C A N  G+A
Sbjct: 3400 ASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKA 3434



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 27/87 (31%), Positives = 46/87 (52%)

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
            PL+D  V EG+P +   +IT+  +  ++WL++G  +     F+    G+   L+I     
Sbjct: 2038 PLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLIIPEADV 2097

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKS 4812
            ED G + C A   AG+  T A ++V+S
Sbjct: 2098 EDEGRYRCEAVNNAGRASTEADILVES 2124



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 29/108 (26%), Positives = 55/108 (50%), Gaps = 2/108 (1%)

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            + E D++I  E   +L    PP+     R+ ++ EG     ++ ++G+P+P V WFK+G+
Sbjct: 2179 IAEEDLRIDVEQTAALPKPIPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGK 2238

Query: 305  RL--INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
             +  +   + E+       TL ++  + SD+G Y   A N  G + +S
Sbjct: 2239 PVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSS 2286



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 70/248 (28%), Positives = 102/248 (41%), Gaps = 23/248 (9%)

Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRA 3497
            A FE  +T   +P  KVEW  N   +++G RF    D     L +  +  +D GE  C A
Sbjct: 2854 AIFEVEITGKPEP--KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTA 2911

Query: 3498 YNNYGEAVTTASMKVQGKRNIILESQL-PKGMEGTIDKIAALEGYSGTVDTLTPEAESGN 3556
             N+ G   + AS+ V+ K +   E  + P G E        +E          P  E+G 
Sbjct: 2912 TNSAGTVTSMASLIVRDKPSEQTELYIKPVGQE-------PVEMQFQVPFETEPTDEAG- 2963

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV- 3615
             P+F        + E S    E  +         VEW  +G+ L+  S + T+   G V 
Sbjct: 2964 -PKFLQRLELKEVVEGSRTDLEVEV--SGKPKPVVEWLKDGE-LVKPSSLMTLETEGQVH 3019

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
             L I      D G YTC A N+ GE  VSC  ++     ++ E   P  F     S+Q +
Sbjct: 3020 TLTIMNTTLDDEGEYTCIAKNKVGE--VSCTAEL-----LVEEGMRPPQFIVKPSSLQIM 3072

Query: 3676 EETLHKRE 3683
            E  + K E
Sbjct: 3073 EGKMAKFE 3080



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 32/101 (31%), Positives = 56/101 (55%), Gaps = 3/101 (2%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            + VA  + P+F   L   T ++EG S  ++ ++   P+P  +V WY NGK++Q       
Sbjct: 2292 LHVAPKEPPKFERNLKDIT-IAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHVDI 2348

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +D   ++L ++    + SG+YTC A N +GQ  S+ RL++
Sbjct: 2349 VHDDEHSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 63/229 (27%), Positives = 87/229 (37%), Gaps = 39/229 (17%)

Query: 636  PPQFI--VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
            PP F    P       EGG I FE  +   G P   +EW K+   I  SS +        
Sbjct: 3251 PPHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDT 3308

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753
             SL +  +   DSG YTC A +  G+A+       T    IE +     T Q+I  +   
Sbjct: 3309 YSLTIRGVGPDDSGAYTCTATNECGMAKR------TYNIDIEASEPKGSTPQFIDLM--- 3359

Query: 754  SKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI 813
               Q  E  E QT                     A FE  +     P+  +EW+K+G P+
Sbjct: 3360 ---QPVEVTEGQT---------------------ATFECTVKGYPRPS--IEWFKNGLPL 3393

Query: 814  TASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
              + RI S +     SL I     +D G+Y   A N  G+A     + V
Sbjct: 3394 KENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 4/93 (4%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            PQF   +  +E  EG     EC ++  G     +EWF NG P+K   R    YE    +L
Sbjct: 3353 PQFIDLMQPVEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENERIASTYEGALSSL 3410

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             +     +D G Y C A N  G+A  SCA  ++
Sbjct: 3411 TINQCTIDDEGNYKCVARNSFGKA--SCATELL 3441



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK--TGHRFRPAYEFDYV 1368
            P+F  AL +IE  EG  V L  R+   G     V+WF +GKP+      RF      +  
Sbjct: 2200 PEFKSALRDIEVNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             L +      D+G Y C+A N  GE  +SC + V+
Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVL 2292



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 28/98 (28%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P F   +KDI +AE  +  F+ ++   G P+ +V W  NG  ++  + +  +HD  + 
Sbjct: 2298 EPPKFERNLKDITIAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHS 2355

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
            +L + +   + SG YTC A NE+G+  +++ L +   A
Sbjct: 2356 SLILMHCPLDLSGKYTCVAENEVGQVQSAARLHITELA 2393



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 52/167 (31%), Positives = 74/167 (44%), Gaps = 13/167 (7%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E+ +E E   PP+F V+   ++ + EG    F+ RV   G P   ++W  +GRP   G R
Sbjct: 3050 ELLVE-EGMRPPQFIVK-PSSLQIMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRR 3105

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
                 +     L I      D GEYTC AT+K G      K +CS +  +V E+ +P   
Sbjct: 3106 FQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAG------KDSCSVEL-LVDEAVVPPEF 3158

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850
               KI  +E      A  +  I  TP   +T  K   V   +G RFE
Sbjct: 3159 V-RKISNIELTEGEIARFDVRITGTPAPEVTWYKDE-VPIEDGGRFE 3203



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE 1628
            +VDE     P     + N+E+ EG+ A F+ R+        +V WY +  P++ G RF  
Sbjct: 3148 LVDEAVVP-PEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEI 3204

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSG 1665
             ++    +L I  C   D+G+Y+C+A N  G+A   G
Sbjct: 3205 YSDDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYG 3241



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748
            DE   PP F  +I  NI++ EG    FD R+   G P   + W+ +  P   G R    +
Sbjct: 3150 DEAVVPPEFVRKIS-NIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYS 3206

Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            D    +L I      D G Y+C+ATN+ G A+   ++T
Sbjct: 3207 DDDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELT 3244



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 32/94 (34%), Positives = 48/94 (51%), Gaps = 4/94 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ--QGHRFKTTYDFGYV 2035
            P+F   +++ EV EG+ V L   +T    P   V+W+ +G+PV      RF+        
Sbjct: 2200 PEFKSALRDIEVNEGNTVTLRIHVT--GSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             L I  A   DTG Y+CKA N+ GE  ++ +V V
Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDV 2291



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+F   +   + + EG  A FE  ++  G     +EW K+G P++ + RI + +     +
Sbjct: 3353 PQF-IDLMQPVEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENERIASTYEGALSS 3409

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            LTI   T+ D G+Y C A N+ G+A+ +  L +
Sbjct: 3410 LTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP+F   LK +T  EG    F+ ++   G P  K+ W  NG+ ++       +    + S
Sbjct: 2299 PPKFERNLKDITIAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSS 2356

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            L ++   +  SG+YTC A +  G  ++ A LH+T  A
Sbjct: 2357 LILMHCPLDLSGKYTCVAENEVGQVQSAARLHITELA 2393



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 33/94 (35%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E + E+  + PQFI     L ++ EG+ A FEA+++ +  P   VEW +DGRPI    R 
Sbjct: 3050 ELLVEEGMRPPQFIVKPSSL-QIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRF 3106

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
               F      L I+  +  D G YT  A +K G+
Sbjct: 3107 QIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGK 3140



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 32/88 (36%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  +  +   EG    FEC V+    P+  IEWF N  PL    R  ST++ +  SL I
Sbjct: 3355 FIDLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSLTI 3412

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +D G Y C A NS G A+ +  L
Sbjct: 3413 NQCTIDDEGNYKCVARNSFGKASCATEL 3440



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 98/473 (20%), Positives = 180/473 (38%), Gaps = 68/473 (14%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRL-TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G PK  V W ++  PI  ++ +  +++D  Y  + +K    +D G Y C A N +G   T
Sbjct: 4526 GKPKPTVTWTKDSKPITETDHIQVSVYDDTYTLI-IKSPTDKDEGIYKCTASNSVG---T 4581

Query: 1797 SSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856
            SS +F        ++ +    + K +  +D   +   +DVE                 ++
Sbjct: 4582 SSQMF-------DVDIKGTDWMLKSKD-DDFPSFVDEDDVEA---------------FEM 4618

Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGE 1916
            ++  S      +   P P   V+W  + K L                L I +   +D G 
Sbjct: 4619 TDEGSIRMTVIVRGKPKP--EVKWSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGT 4676

Query: 1917 YTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVE 1976
            Y C A+N  G  + S  +NV +++S  RD Q +  + K               D+  +  
Sbjct: 4677 YKCTAVNRAGTNIRSFVVNVNTEDSTQRD-QRQMVIRK---------------DEGSITF 4720

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            +   G  I+     +G  V  ++T     D T  +             R  +  D G   
Sbjct: 4721 EDVPGNIIRPKFTEDGSFVPFQSTNEDRQDDTHTLT-----------IREPSPNDTGSYK 4769

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA--KSGLYLDTLDEQRLKKIQELEKY 2094
              I   Y   T T+  +  + + E       KV+   +  L  +T+   ++ + ++  + 
Sbjct: 4770 CTISSDYGRSTRTFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEETMSVTKILQDEKALEP 4829

Query: 2095 ERPKP--IEE--EQPGQRPVFLTA--LTSLENLKEGDRAHFECRVEPINDPHLTIDWFHN 2148
             RP+   IE+   +P Q P+F+    +   E  +EGD    +  V+    P  +++W  +
Sbjct: 4830 ARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGD---IKMTVKVTGKPKPSVEWLKD 4886

Query: 2149 GQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             + + +    + T +    +L I      D G Y  K TN +G    T  +KV
Sbjct: 4887 DRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKV 4939



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 50/196 (25%), Positives = 89/196 (45%), Gaps = 19/196 (9%)

Query: 2055 TNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPV---F 2111
            T A+G+     ++ +D K+G     + E ++    E+ + +    +E+     +P+   F
Sbjct: 2144 TIAIGQEPPAVTLTLDGKAGFDFQAV-ELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEF 2202

Query: 2112 LTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDFGYV-AL 2169
             +AL  +E + EG+      R+     P   +DWF +G+ +    HR       G V  L
Sbjct: 2203 KSALRDIE-VNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTL 2259

Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE-AQGH 2228
             I      D+G Y+CKA N  GE  ++C + V  H   +   + P     ++ +  A+G 
Sbjct: 2260 VIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVL-H---VAPKEPPKFERNLKDITIAEGC 2315

Query: 2229 STRIEVE-----EPKI 2239
            STR +V+     EPK+
Sbjct: 2316 STRFDVQVTGSPEPKV 2331



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 2/97 (2%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            E   PP+F   PS L + E   A FE R+  +      VEW  +G+P+  G R +   + 
Sbjct: 3055 EGMRPPQFIVKPSSLQIMEGKMAKFEARVSGL--PGPEVEWLRDGRPIKPGRRFQIEFEK 3112

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
               +L I      D G YTC AT++ G+ + S +L V
Sbjct: 3113 DRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLV 3149



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 33/85 (38%), Positives = 44/85 (51%), Gaps = 3/85 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   +SNIE L EGE A F+ R+T T  P  +V WY +   ++ G RF  + D     
Sbjct: 3156 PEFVRKISNIE-LTEGEIARFDVRITGTPAP--EVTWYKDEVPIEDGGRFEIYSDDDKHS 3212

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEA 3504
            L I      D+G Y C+A N  G+A
Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQA 3237



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 115/502 (22%), Positives = 188/502 (37%), Gaps = 74/502 (14%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W KDG PV  +  I          L IKS T   AG Y C A N  G  +    +TI 
Sbjct: 3885 VSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLYAGTYKCVATNRRGTNSRDFEVTIE 3944

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062
            T +            E I + +D     + T     I + P    P +    I E     
Sbjct: 3945 TGE----------AAEHITFQQD-----EETVRAQFIEKGPYAPVPFE----ITEEGDVK 3985

Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
             + R+         ++W+ +G+ ++  + I+   D     + I     +D+G Y  + +N
Sbjct: 3986 LQVRI--CGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKN 4043

Query: 1123 AAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQP 1182
             AG+A  +  + +E   ++  S   RG  E + H+   KF++    + E+S         
Sbjct: 4044 IAGKATRTFDVDIE---AVKPSRHVRG--ELSEHLILPKFID----VTEVS--------- 4085

Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242
               P  VS   +  L  +L   GD    V+W  +G  +    R+    D     L I+ A
Sbjct: 4086 ---PYRVSYDGDFTLTVKLSGSGD----VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGA 4138

Query: 1243 TSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVR 1302
            T  D G Y     N  G    S  + +    D+   T    A E  +L+         + 
Sbjct: 4139 TEDDLGTYKCVVTNKAGFDTRSFDIGL---EDLRPHT---FAYEPSELV-----APYYLE 4187

Query: 1303 EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPA 1362
            + +T  Q              +  +V L  R++  G     V+W  N +P+     F   
Sbjct: 4188 DGVTAFQ------------MTDAGDVKLTVRVR--GKPKPTVKWTKNDEPVVPSSHFSVL 4233

Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
             E D  +L +      D GVY   ATN+ G  + +    V  + D    ++     E  +
Sbjct: 4234 MEDDVFSLLIRKPSKTDKGVYKVIATNEGG--INTKRFNVDIEWDETTTTRVVDDREAPR 4291

Query: 1423 YLED-TSRYKKTDIIDESVTIK 1443
            +L+D  S Y+ T   D  +T+K
Sbjct: 4292 FLDDGISSYEFTSGGDVKLTVK 4313



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 10/142 (7%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR-PAYEFDYVA 1369
            P+F+  L N+    G  + LECR+   G    +V WF + K I+   RF       D   
Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCV 2453

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK-------KDLILESQHPSGLEKIQ 1422
            L +  V P+D G Y C ATN  G+  T   L V  +       K+L+       G E+ +
Sbjct: 2454 LTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGNPPFFVKELVDIDVTEGGHERFE 2513

Query: 1423 YLEDTSRYKKTDIIDESVTIKP 1444
             + D     + D     + I+P
Sbjct: 2514 VVVDGYPKPEIDWYKNDILIRP 2535



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 44/199 (22%), Positives = 83/199 (41%), Gaps = 8/199 (4%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G PP F     DI D++EG   H    ++  G     I+W+ N   I    +        
Sbjct: 2490 GNPPFFVKELVDI-DVTEG--GHERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGD 2546

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L +   +  ++G  +C+A N  GQA  S  ++  +K+    P+ T  + ++  +  G
Sbjct: 2547 HHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTI--PPKITQRLHDLS-IDAG 2603

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            ++ +   TV     P+  ++W+ + + + +   +   +      L +      D+G Y C
Sbjct: 2604 KTVNL--TVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTSSLVLVGVDTPDTGVYRC 2661

Query: 3225 RAYNKYGEDFTRATINCYG 3243
              +N  GED T + I   G
Sbjct: 2662 LVFNPAGEDSTNSKITVKG 2680



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            ++I+EK + P+  +   D  +  GK      +  G P P V WF++D +I ++    I  
Sbjct: 2580 VQINEKTIPPKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEITNEDGVDIET 2639

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            +   + +L++  V   D+GV  C+  N +GE +   ++ V
Sbjct: 2640 SHCTS-SLVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITV 2678



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 2/79 (2%)

Query: 87   GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146
            GN +   K+ G P P VSWT+ + P+ +    ++R + Q    +L I++  P D G Y C
Sbjct: 4970 GNVRLSVKITGKPVPEVSWTKDEKPVHKIQ--NIRLDHQDDIYTLTIREATPNDSGSYKC 5027

Query: 147  TARNQYGEAICSVYIQPEG 165
            T  N  G++  +  ++ EG
Sbjct: 5028 TLTNDAGKSTRTFSVEIEG 5046



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 2/85 (2%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+FI +  S  + E +  +FE RV     P+  +EW R+G+ +  G R++  ++     
Sbjct: 3059 PPQFIVKPSSLQIMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEFEKDRSV 3116

Query: 3889 LDILYVYAEDSGEYICRAVNDFGED 3913
            L I+     D GEY C A +  G+D
Sbjct: 3117 LTIIDAKLNDEGEYTCVATSKAGKD 3141



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            DE +   P F   + +I + E + A F+ R+   G P   V W ++ VPIE   R     
Sbjct: 3150 DEAVVP-PEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYS 3206

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
            D    +L ++     D+G+Y+C+A NE G+A
Sbjct: 3207 DDDKHSLVIRDCALSDTGSYSCKATNEAGQA 3237



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 3/93 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+FI + +   ++ EG+ A +E R+   P P   VEW  +G+ ++ G R++   +   + 
Sbjct: 3060 PQFIVKPSS-LQIMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEFEKDRSV 3116

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            L I+     D GEYTC A +  G+   S+ L V
Sbjct: 3117 LTIIDAKLNDEGEYTCVATSKAGKDSCSVELLV 3149



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 3/95 (3%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E + ++    P+F+R + ++ EL EG  A F+ ++T    P   V WYKD  PI    R 
Sbjct: 3146 ELLVDEAVVPPEFVRKISNI-ELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRF 3202

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEA 854
                +    SL I      D GSY+ +A N+ G+A
Sbjct: 3203 EIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA 3237



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 5/149 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  ++NI   EG+   F+  +  +  P  ++ W+ +  P+  G R++   D    SL I
Sbjct: 3158 FVRKISNIELTEGEIARFDVRITGT--PAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVI 3215

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTG-DKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
                  D+G Y+CKATN  G A+  G L  T      +F  + P+     E         
Sbjct: 3216 RDCALSDTGSYSCKATNEAGQASCYGELTITFIPVPPHFTEEAPKIPTDFEEGGDITFEA 3275

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQL 2923
               G RP  PD E+ K E  I  ++ + L
Sbjct: 3276 TVSG-RPR-PDVEWHKDEAPISESSHYHL 3302



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 56/198 (28%), Positives = 81/198 (40%), Gaps = 15/198 (7%)

Query: 3590 RVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +VEW  N   + +G R +  +D     L + G    D G   C ATN  G  T    L V
Sbjct: 2867 KVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATNSAGTVTSMASLIV 2926

Query: 3650 KGRQGIILEPQLPSHFKS-GTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVP 3708
            + +       Q   + K  G E ++   +   + E     DE    P+F   ++   +V 
Sbjct: 2927 RDKP----SEQTELYIKPVGQEPVEMQFQVPFETEP---TDEA--GPKFLQRLELK-EVV 2976

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI-ALDIDYIYARDAGE 3767
            EG     D  VE  G P   ++W  +G      S + TL   G +  L I      D GE
Sbjct: 2977 EGS--RTDLEVEVSGKPKPVVEWLKDGE-LVKPSSLMTLETEGQVHTLTIMNTTLDDEGE 3033

Query: 3768 YTCRATNKWGSATTTAKI 3785
            YTC A NK G  + TA++
Sbjct: 3034 YTCIAKNKVGEVSCTAEL 3051



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 40/145 (27%), Positives = 69/145 (47%), Gaps = 9/145 (6%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
            PP+F+ +I ++ +L EG+ A F+ R+     P+  V W+ +   +  G R+  + D    
Sbjct: 3155 PPEFVRKISNI-ELTEGEIARFDVRITGTPAPE--VTWYKDEVPIEDGGRFEIYSDDDKH 3211

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCT---SKENLILDS-QLPRGMEGGLEK 3396
             L I  C   ++G Y C ATN+ G+ S    L  T      +   ++ ++P   E G + 
Sbjct: 3212 SLVIRDCALSDTGSYSCKATNEAGQASCYGELTITFIPVPPHFTEEAPKIPTDFEEGGD- 3270

Query: 3397 LQTLEDSMVRRKDTSVEEEKGKAPV 3421
              T E ++  R    VE  K +AP+
Sbjct: 3271 -ITFEATVSGRPRPDVEWHKDEAPI 3294



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            PQF     + ++ EG     EA ++ +  P   VEW  +GRP++ G RF+  ++     L
Sbjct: 3060 PQFIVKPSSLQIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEFEKDRSVL 3117

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             I+ A   D G Y C AT+  G+   +  + VD
Sbjct: 3118 TIIDAKLNDEGEYTCVATSKAGKDSCSVELLVD 3150



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 2/84 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P+F R + NIE  EG     + R+   G     V W+ +  PI+ G RF    + D  +L
Sbjct: 3156 PEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSL 3213

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEA 1394
             +      D+G Y+C+ATN+ G+A
Sbjct: 3214 VIRDCALSDTGSYSCKATNEAGQA 3237



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F + + NI+ + EG+ A FD R+   G P  +V W+++E  IED  R     D    S
Sbjct: 3156 PEFVRKISNIE-LTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHS 3212

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            + I      D G Y C+A+N  G+
Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQ 3236



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 86/336 (25%), Positives = 124/336 (36%), Gaps = 54/336 (16%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V WF +G P++    +         IL I       AG Y C ATNR G  T S   +V 
Sbjct: 3885 VSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLYAGTYKCVATNRRG--TNSRDFEVT 3942

Query: 3651 GRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEG 3710
               G   E     H      + Q+ EET+  +    IE     P  F        ++ E 
Sbjct: 3943 IETGEAAE-----HI-----TFQQDEETVRAQ---FIEKGPYAPVPF--------EITEE 3981

Query: 3711 GPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTC 3770
            G V    R+   G P   IDWF +GR  +    +   +D     + I     +D G+Y C
Sbjct: 3982 GDVKLQVRI--CGIPFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKC 4039

Query: 3771 RATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPP 3830
               N  G AT T         D+ +E+  P            RG +S    E  I+   P
Sbjct: 4040 IIKNIAGKATRTF--------DVDIEAVKP--------SRHVRGELS----EHLIL---P 4076

Query: 3831 KFI--TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            KFI  T++  + V          ++    D    ++W ++G+++    RY    D     
Sbjct: 4077 KFIDVTEVSPYRVSYDGDFTLTVKLSGSGD----VQWMKDGEVIEDSKRYVIRQDDDLHM 4132

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
            L IL    +D G Y C   N  G D     I  + L
Sbjct: 4133 LTILGATEDDLGTYKCVVTNKAGFDTRSFDIGLEDL 4168



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            Q P     LK+ E+KEG+    + ++  + +A +K  W  + +PLK G  F    +    
Sbjct: 2031 QPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVK--WLKDGEPLKPGDHFKTERHGDTY 2088

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHS 1671
             L I     ED G Y C A+N  G A T    +V S
Sbjct: 2089 FLIIPEADVEDEGRYRCEAVNNAGRASTEADILVES 2124



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 25/76 (32%), Positives = 40/76 (52%)

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
            A F+ +IT K +P ++WL+   LI     F+   +G    L +  +  +D G   C AT 
Sbjct: 2854 AIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRLDDEGEIKCTATN 2913

Query: 4798 AAGQVETSAKLVVKSK 4813
            +AG V + A L+V+ K
Sbjct: 2914 SAGTVTSMASLIVRDK 2929



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 25/66 (37%), Positives = 39/66 (59%), Gaps = 2/66 (3%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T E +VEE     PP F+  P ++ + EG+ A+F  RV+G P P V WL +G  I  G R
Sbjct: 3048 TAELLVEEGMR--PPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRR 3105

Query: 4157 YKLTYD 4162
            +++ ++
Sbjct: 3106 FQIEFE 3111



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 6/96 (6%)

Query: 1836 VEVAVNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            VE+ V++A   P F+ +++   +L+EG+ A ++ RI   P P   V WY +   ++ G R
Sbjct: 3145 VELLVDEAVVPPEFVRKISN-IELTEGEIARFDVRITGTPAPE--VTWYKDEVPIEDGGR 3201

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            +   +D    +L I      D+G Y+CKA N  GQA
Sbjct: 3202 FEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA 3237



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 3/104 (2%)

Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468
            D    E KG  P F   +  +E + EG+ A FE   T    P   +EW+ NG  LK   R
Sbjct: 3342 DIEASEPKGSTPQFIDLMQPVE-VTEGQTATFEC--TVKGYPRPSIEWFKNGLPLKENER 3398

Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
              +  +     L I+    +D G Y C A N++G+A     + V
Sbjct: 3399 IASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 5/100 (5%)

Query: 2639 QQAPIF--TTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            +Q PIF  T  +K ++   EG    ++  V+    P   +EW K+   + + + +K T +
Sbjct: 4845 KQEPIFIETDEVKPFEVTEEGD---IKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEE 4901

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              + +L+I      D G+YT K TN +G    T  +K+ED
Sbjct: 4902 DDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVED 4941



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 36/112 (32%), Positives = 55/112 (49%), Gaps = 5/112 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F +PL +   V EGK   L+ ++  +  P   V+W  +G  +  G  FKT        
Sbjct: 2033 PFFQKPLKDKE-VKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTYF 2089

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE-QAIEQ 1287
            L I  A   D G Y   AVN+ G A T A + ++E +D  ++ ++E Q +EQ
Sbjct: 2090 LIIPEADVEDEGRYRCEAVNNAGRASTEADI-LVESADEGSEPEDEPQQMEQ 2140



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028
            K   P+F+  +Q    + E +T  FEC +   G P   +EWF NG PL    R    Y+ 
Sbjct: 3349 KGSTPQFIDLMQP-VEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENERIASTYEG 3405

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYG 4055
               ++       +D G Y C A N +G
Sbjct: 3406 ALSSLTINQCTIDDEGNYKCVARNSFG 3432



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 3/93 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P+F R L+D+  + EG +  F+ Q+T   +P  +V WY +G+ +     +  + +  + S
Sbjct: 2300 PKFERNLKDI-TIAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHVDIVHDDEHSS 2356

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            L +MH   + +G YT  A N++G+  S A + +
Sbjct: 2357 LILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 41/163 (25%), Positives = 67/163 (41%), Gaps = 11/163 (6%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP  T+++    +   +     V+F G P PL+KW+ ++  I N     I T    S L+
Sbjct: 2588 PPKITQRLHDLSIDAGKTVNLTVKFFGTPEPLVKWFMDDEEITNEDGVDIETSHCTSSLV 2647

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVE----EKRRQGRGGIV-------PPSFTL 4518
            +  V   D+ V+  +  N  G    ++ + V+    E   Q     V        PSFT 
Sbjct: 2648 LVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKGVKIEPAIQEPVEAVLSLPRGEAPSFTK 2707

Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
               +  V     VRL+ +VTG     V+   N +  +  IR +
Sbjct: 2708 KITDKQVVENDAVRLEVEVTGFTHEPVFTADNWQTKRRCIRER 2750



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
            ++ VE+ EGQ A FE  +      +  +EW+ N  PLK   R   T      +L I  C 
Sbjct: 3359 MQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSSLTINQCT 3416

Query: 1644 PEDSGTYTCRAINALGEA 1661
             +D G Y C A N+ G+A
Sbjct: 3417 IDDEGNYKCVARNSFGKA 3434



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 6/131 (4%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P+F+  ++   ++ EGQ+A FE  V+       ++EW+ NG  +    RI + ++    +
Sbjct: 3353 PQFIDLMQPV-EVTEGQTATFECTVKGYP--RPSIEWFKNGLPLKENERIASTYEGALSS 3409

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID---TSSIHRGLYEKTRHIEE 1159
            L I     +D G Y  VARN+ G+A  +  + V+   S +   +  I     E  R  E 
Sbjct: 3410 LTINQCTIDDEGNYKCVARNSFGKASCATELLVDEADSPEDQVSGKIMNFDRELKRDFEA 3469

Query: 1160 SKFVEPMYQIE 1170
                 P  Q+E
Sbjct: 3470 EDLFNPKVQVE 3480



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 1/102 (0%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            VEWLKD RPV + S I         +LTI+  T  D G YT +  N +G  T + ++ + 
Sbjct: 4881 VEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVE 4940

Query: 1003 -TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKP 1043
             T   +   +  P  +E   ++   S         VKIT KP
Sbjct: 4941 DTTTSLFEGTVRPKFIEDDSFVPFESTEEGNVRLSVKITGKP 4982



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 26/93 (27%), Positives = 43/93 (46%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP F K ++   V E +  + +V+    P   +KW ++  P+K    F+         L
Sbjct: 2031 QPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFL 2090

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            II +  VED   +   A N  G A   A+++VE
Sbjct: 2091 IIPEADVEDEGRYRCEAVNNAGRASTEADILVE 2123



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 3/90 (3%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            EE  + P F V  S+++ + EG+ A FEAR++    P  +VEW  +G+ +K G RF+   
Sbjct: 3054 EEGMRPPQFIVKPSSLQ-IMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEF 3110

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGE 3503
            +    +L I      D GEY C A +  G+
Sbjct: 3111 EKDRSVLTIIDAKLNDEGEYTCVATSKAGK 3140



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 631  DRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR 690
            D    PP+F+  + ++   EG    F+ RI   G P  ++ W K+   IE   RF     
Sbjct: 3150 DEAVVPPEFVRKISNIELTEGEIARFDVRI--TGTPAPEVTWYKDEVPIEDGGRFEIYSD 3207

Query: 691  FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
                SL +    + D+G Y+C+A +  G A     L +T
Sbjct: 3208 DDKHSLVIRDCALSDTGSYSCKATNEAGQASCYGELTIT 3246



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 72/305 (23%), Positives = 118/305 (38%), Gaps = 36/305 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     + WF +G  +  +  I       + +L I       +GTY C ATN+ G    
Sbjct: 3878 TGFPEPDVSWFKDGIPVVPNEHIVYHIRDDVHILIIKSPTPLYAGTYKCVATNRRGTNSR 3937

Query: 3131 QAEISVKL-ECVDKSKGQKPRFTTHIQNIE-------GLKDGQSAHFECTVVPVDDPDMK 3182
              E++++  E  +    Q+   T   Q IE         +  +    +  V     P  +
Sbjct: 3938 DFEVTIETGEAAEHITFQQDEETVRAQFIEKGPYAPVPFEITEEGDVKLQVRICGIPFPE 3997

Query: 3183 IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCY 3242
            I+W+ +G+ +     IK  SD     + I      D+G+Y C   N  G+  TR      
Sbjct: 3998 IDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGK-ATRTF---- 4052

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF 3302
                V +E+++P    +    E L               PKFI  + +V+         F
Sbjct: 4053 ---DVDIEAVKPSRHVRGELSEHL-------------ILPKFI-DVTEVSPYRVSYDGDF 4095

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
               +      D  V+W  +G+ +    RY    D  + +L IL   E++ G Y+CV TNK
Sbjct: 4096 TLTVKLSGSGD--VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNK 4153

Query: 3363 LGRDS 3367
             G D+
Sbjct: 4154 AGFDT 4158



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 83/404 (20%), Positives = 158/404 (39%), Gaps = 40/404 (9%)

Query: 4040 PEDSGEYLCRATNLYGMD------ETKAVIKTTGKPGI-----VYDSQLPKHMKSIEKIR 4088
            P D+G Y C  ++ YG        E  + +    +P        ++  L +   S+ KI 
Sbjct: 4762 PNDTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEETMSVTKIL 4821

Query: 4089 EMEASWQ-VTPEQ-VVEE--SKARCPPVFVSLPDAV---TVEEGEWARFCCRVTGHPKPR 4141
            + E + +   PE+ ++E+  SK +  P+F+   +       EEG+  +   +VTG PKP 
Sbjct: 4822 QDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGD-IKMTVKVTGKPKPS 4880

Query: 4142 VMWLLNGNTIVNGSRYKLT-YDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVI 4200
            V WL +   +++ S  K+T  D +Y   I +  + D G   V              +KV 
Sbjct: 4881 VEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKV- 4939

Query: 4201 PRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKE 4260
               D    + +   RP + E   +       E T E    L  +      PE+     ++
Sbjct: 4940 --EDTTTSLFEGTVRPKFIEDDSF----VPFESTEEGNVRLSVKITGKPVPEVSWTKDEK 4993

Query: 4261 PETEWQQSVKRKKNEEYYNKLQE-LENEQVIKESRLR----ESTHQYAIPGDKVTSNTVA 4315
            P  + Q      +++ Y   ++E   N+    +  L     +ST  +++   ++   T  
Sbjct: 4994 PVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSV---EIEGETKP 5050

Query: 4316 KSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGD 4375
            +       +     EE      + +V  KP +   +   +  +EV   K K T++E    
Sbjct: 5051 EKGKPTEREGKPLEEEELPVSAETEVEVKPLVETITRKEIKVEEVKPKKGKPTEREA--- 5107

Query: 4376 KEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQP 4419
            K    K    E   I  +   +E+ +E P+   +  +  +K++P
Sbjct: 5108 KPFEEKPLIEEELPISAEKVVEEKPLEKPIARKEKKV--EKVKP 5149



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 2/113 (1%)

Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367
            +Q P F + L + E  EG    L+ ++  + +    V+W  +G+P+K G  F+     D 
Sbjct: 2030 IQPPFFQKPLKDKEVKEGKPFKLDVKITALPEAN--VKWLKDGEPLKPGDHFKTERHGDT 2087

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK 1420
              L +     ED G Y C+A N  G A T   + V +  +       P  +E+
Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQ 2140



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 8/144 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA-SNRLTTMHDFGYV- 1768
            P F   ++DI V E        R+   G PK  V+W ++G P+    +R   +   G V 
Sbjct: 2200 PEFKSALRDIEVNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L +K     D+G Y C+A N  GE  +S  + V   A  +   + E  L+ I   E  S
Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKE-PPKFERNLKDITIAEGCS 2316

Query: 1829 RYQRREDVEVAVNQAPRFITQLNG 1852
                R DV+V  +  P+     NG
Sbjct: 2317 ---TRFDVQVTGSPEPKVFWYHNG 2337



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 11/132 (8%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E   +P+F   + + +SI  G     E R+   G    +V W KD + +   SR +  
Sbjct: 2389 ITELAIQPKFAERLTN-VSISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFE 2445

Query: 962  FNFGYVA-LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK-------KDIIAESQH 1013
               G V  LTI+ VT  D G Y C A N  GQ  T A LT+  +       K+++     
Sbjct: 2446 TRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGNPPFFVKELVDIDVT 2505

Query: 1014 PGGLEKIQYLED 1025
             GG E+ + + D
Sbjct: 2506 EGGHERFEVVVD 2517



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 2/105 (1%)

Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
            ++ VA    P F  +      ++EG    +E  ++ YP P   ++WY N  +++ G ++ 
Sbjct: 2483 ELTVAKRGNPPFFVKELVDIDVTEGGHERFEVVVDGYPKPE--IDWYKNDILIRPGPKFD 2540

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
                     L +     E++G+ TCKA N+ GQA+ S  + +  K
Sbjct: 2541 IKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 2/95 (2%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P     L ++++ EG    FE  ++       +++WY N+  ++ G +F    +     L
Sbjct: 2493 PFFVKELVDIDVTEGGHERFE--VVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTL 2550

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
             +  C PE++G  TC+A N+ G+A+ S    ++ K
Sbjct: 2551 IVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   + DI V E     FE  ++  G PK  ++W +N + I    +        +  L
Sbjct: 2493 PFFVKELVDIDVTEGGHERFE--VVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTL 2550

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             +K   PE++G  TC+A N  G+A+ S  + +  K
Sbjct: 2551 IVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 9/149 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F +    +++ E + A FEAR+  +  P+  VEWLR+G PI+   R     +     L
Sbjct: 3060 PQFIVKPSSLQIMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEFEKDRSVL 3117

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +      D G YTC A ++ G+   S  L V  +A +  E      ++KI  +E +   
Sbjct: 3118 TIIDAKLNDEGEYTCVATSKAGKDSCSVELLV-DEAVVPPE-----FVRKISNIELTEGE 3171

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
              R DV +    AP  +T       + +G
Sbjct: 3172 IARFDVRITGTPAPE-VTWYKDEVPIEDG 3199



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 6/128 (4%)

Query: 3800 PQGMSGEK--IKELERGRISDAPKEEPI-VSTPPKFITQIKSHTVEESEGVRFECRVEPK 3856
            P  +SG+   + E E G++  A +     ++  PKF  ++ + ++   + +  ECRV  K
Sbjct: 2363 PLDLSGKYTCVAENEVGQVQSAARLHITELAIQPKFAERLTNVSISSGDTIVLECRVTGK 2422

Query: 3857 EDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS-LDILYVYAEDSGEYICRAVNDFGEDFT 3915
              P+ ++ W+++ K +    R+      G V  L I  V  +D G Y C A N  G+D T
Sbjct: 2423 --PRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDT 2480

Query: 3916 KATISCKK 3923
             A ++  K
Sbjct: 2481 VAELTVAK 2488



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 6/98 (6%)

Query: 1435 IIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494
            ++DE+V + P FV +  +IE + EG+   F+ ++        +V W+K+  P+  G RF 
Sbjct: 3148 LVDEAV-VPPEFVRKISNIE-LTEGEIARFDVRITGTPAP--EVTWYKDEVPIEDGGRFE 3203

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
               D    +L I D    D+G Y+C+A N  G  + SC
Sbjct: 3204 IYSDDDKHSLVIRDCALSDTGSYSCKATNEAG--QASC 3239



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 4/111 (3%)

Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            +  E   S P F+  L  P  V+EG+    EC ++  G P   +EWF NG  +    R  
Sbjct: 3344 EASEPKGSTPQFID-LMQPVEVTEGQTATFECTVK--GYPRPSIEWFKNGLPLKENERIA 3400

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTD 1278
            + Y+    +L I   T  D G Y   A N  G A + A   +++ +D   D
Sbjct: 3401 STYEGALSSLTINQCTIDDEGNYKCVARNSFGKA-SCATELLVDEADSPED 3450



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            I+P F  +P   + V EG+    + K+  + ++N+K  W K+G+P+  G  F+       
Sbjct: 2030 IQPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVK--WLKDGEPLKPGDHFKTERHGDT 2087

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVG 1526
              L I +   ED G Y C AVN  G
Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAG 2112



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L   D + EG H   E  V+    P  +I+W+KN + +  G +          T
Sbjct: 2493 PFFVKELVDID-VTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEHGDHHT 2549

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            L +   R +++G  TCKA N  G+A+ +  ++I ++
Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578
            EL EG+ A ++ R+   G P+    WY + V ++ G RF    D    +L I     +D 
Sbjct: 3166 ELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDT 3223

Query: 2579 GLYMCKAINRAG 2590
            G Y CKA N AG
Sbjct: 3224 GSYSCKATNEAG 3235



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/80 (37%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 922  KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
            +EGG   FEA +   G     VEW KD  P+  SS      +    +LTI+ V   D+G 
Sbjct: 3266 EEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGA 3323

Query: 982  YTCRAYNAIGQATTSANLTI 1001
            YTC A N  G A  + N+ I
Sbjct: 3324 YTCTATNECGMAKRTYNIDI 3343



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 83/399 (20%), Positives = 141/399 (35%), Gaps = 55/399 (13%)

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            L I    P D+G Y C   ++YG +  T ++++        +   PK +E   +K  + E
Sbjct: 4755 LTIREPSPNDTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYPK-VEPFHEKPLSEE 4813

Query: 3540 GYSGT--------VDTLTPE--------AESGNPPEFTTTPSDLILSENSSAHFECRLIP 3583
              S T        ++   PE        ++    P F  T              +  +  
Sbjct: 4814 TMSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKV 4873

Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643
                   VEW  + +P+L+ S +K   +     L I    + D G+YT K TN  G  T 
Sbjct: 4874 TGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTR 4933

Query: 3644 SCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKD 3703
            +  ++V+     + E  +   F                     IED+   P   T E   
Sbjct: 4934 TFDVKVEDTTTSLFEGTVRPKF---------------------IEDDSFVPFESTEE--- 4969

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
                   G V    ++   G P   + W  + +P      +   +      L I      
Sbjct: 4970 -------GNVRLSVKI--TGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPN 5020

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE- 3822
            D+G Y C  TN  G +T T  +    + +   E   P    G+ ++E E    ++   E 
Sbjct: 5021 DSGSYKCTLTNDAGKSTRTFSV--EIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEV 5078

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861
            +P+V T  +   +IK   V+  +G   E   +P E+  L
Sbjct: 5079 KPLVETITR--KEIKVEEVKPKKGKPTEREAKPFEEKPL 5115



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 2/95 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F + L +I+  EG +   E  +   G     ++W+ N   I+ G +F      D+  L
Sbjct: 2493 PFFVKELVDIDVTEGGHERFEVVVD--GYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTL 2550

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
             +    PE++G  TC+A N  G+A+ SC +++  K
Sbjct: 2551 IVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 7/126 (5%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+F+ +I +  + E E  RF+ R+     P+  + WY++   +  G R+    D    S
Sbjct: 3155 PPEFVRKISNIELTEGEIARFDVRITGTPAPE--VTWYKDEVPIEDGGRFEIYSDDDKHS 3212

Query: 3889 LDILYVYAEDSGEYICRAVNDFGED--FTKATISCKKLPDIILQN--QVPRGMKRSEALT 3944
            L I      D+G Y C+A N+ G+   + + TI+   +P    +   ++P   +    +T
Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQASCYGELTITFIPVPPHFTEEAPKIPTDFEEGGDIT 3272

Query: 3945 QMEATI 3950
              EAT+
Sbjct: 3273 -FEATV 3277



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G+ P+F      + ++E  +A FEC +      S  +EWF NG PL    R+ +  +   
Sbjct: 3350 GSTPQFIDLMQPVEVTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGAL 3407

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              L I      D G Y C A N  G+A+ + +L V
Sbjct: 3408 SSLTINQCTIDDEGNYKCVARNSFGKASCATELLV 3442



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 82   RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDE 141
            +  + G+ K   ++ G P P V+WT+   P+ E +   +   + T   +L+IK     DE
Sbjct: 4511 QLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDT--YTLIIKSPTDKDE 4568

Query: 142  GEYTCTARNQYG 153
            G Y CTA N  G
Sbjct: 4569 GIYKCTASNSVG 4580



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 3/111 (2%)

Query: 1831 QRREDVEVAVNQA-PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            ++R   E+ +    P F  +     ++ EG+    + +I   P+ N  V+W  +G+ L+ 
Sbjct: 2018 KKRSTAEIMMGDIQPPFFQKPLKDKEVKEGKPFKLDVKITALPEAN--VKWLKDGEPLKP 2075

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            G  ++T        L I     ED G Y C+A+NN G+A +   + V+S +
Sbjct: 2076 GDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESAD 2126



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 3/112 (2%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            +PP F   ++D  ++ EG+    + ++  +  P+  V+W  +G+ L  G  ++T      
Sbjct: 2031 QPPFFQKPLKD-KEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGME 3391
              L I     E+ G Y C A N  GR ST+A++   S +        P+ ME
Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQME 2139



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 29/92 (31%), Positives = 37/92 (40%), Gaps = 3/92 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F   +KD  +V EG P   D ++  +  P   + W  +G P   G    T       
Sbjct: 2032 PPFFQKPLKDK-EVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTY 2088

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             L I      D G Y C A N  G A+T A I
Sbjct: 2089 FLIIPEADVEDEGRYRCEAVNNAGRASTEADI 2120



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P+F + +K+  + EG     +  +T    P  +V WY NG+ VQ        +D  + 
Sbjct: 2298 EPPKFERNLKDITIAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDDEHS 2355

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +L +++   + +G Y C A N VG+  + + + +
Sbjct: 2356 SLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            +P+F + + N  ++ G  + LE  +T    P  +V W+ + + ++Q  RF      G V 
Sbjct: 2395 QPKFAERLTNVSISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVC 2452

Query: 2037 -LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074
             L I     +D G+Y C ATN  G+  T + + V AK G
Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTV-AKRG 2490



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 39/129 (30%), Positives = 55/129 (42%), Gaps = 7/129 (5%)

Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228
            +EE  +     V+P S    + EGK    E R+   G P   VEW  +GR +  G RF+ 
Sbjct: 3053 VEEGMRPPQFIVKPSSLQ--IMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRRFQI 3108

Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQI 1288
             ++     L II A   D GEYT  A +  G    S  + V    + V   +  + I  I
Sbjct: 3109 EFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLV---DEAVVPPEFVRKISNI 3165

Query: 1289 QLLEDAARR 1297
            +L E    R
Sbjct: 3166 ELTEGEIAR 3174



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 25/88 (28%), Positives = 41/88 (46%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P+  VEW ++  PI  S+           +L ++ V P+DSG YTC A NE G A  +
Sbjct: 3279 GRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRT 3338

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLE 1825
              + +++        Q    +Q ++  E
Sbjct: 3339 YNIDIEASEPKGSTPQFIDLMQPVEVTE 3366



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100
            + P+F   LK    I EG S  F+ +V    +    V WY NGK +   + +   HD  +
Sbjct: 2298 EPPKFERNLKDIT-IAEGCSTRFDVQVTGSPE--PKVFWYHNGKLVQPRDHVDIVHDDEH 2354

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             +L +     + SG YT VA N  G+ Q +A + +
Sbjct: 2355 SSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            + P+F R L +I   EG +   +  +Q  G    +V W+ NGK ++        ++ ++ 
Sbjct: 2298 EPPKFERNLKDITIAEGCSTRFD--VQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHS 2355

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L L+    + SG YTC A N++G+  ++  L +
Sbjct: 2356 SLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 5/99 (5%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P+F  ++ +  S+   +T   EC++   G P  +V WF + K +   +RF+     G V 
Sbjct: 2396 PKFAERL-TNVSISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVC 2452

Query: 4033 -MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPG 4070
             +    V P+D G Y C ATN  G D+T A + T  K G
Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAEL-TVAKRG 2490



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E+T+  ++ NPP F  E+ D IDV EGG   F+  V+  G P   IDW+ N      G +
Sbjct: 2483 ELTVA-KRGNPPFFVKELVD-IDVTEGGHERFEVVVD--GYPKPEIDWYKNDILIRPGPK 2538

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
                       L +      + G+ TC+A N  G A  +  +  + K
Sbjct: 2539 FDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 5/89 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+F+   + +E V EGQ   FEC ++     +  +EWFKNG P+    R    ++    +
Sbjct: 3353 PQFIDLMQPVE-VTEGQTATFECTVKGYPRPS--IEWFKNGLPLKENERIASTYEGALSS 3409

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
            L I     +D G Y C A N  G  + SC
Sbjct: 3410 LTINQCTIDDEGNYKCVARNSFG--KASC 3436



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 2/91 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F  +L +I   EG +  F+  V  S +P  K+ W+ N K +         HD  + SL +
Sbjct: 2302 FERNLKDITIAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHVDIVHDDEHSSLIL 2359

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
             H   + SG YTC A N  G   ++  L  T
Sbjct: 2360 MHCPLDLSGKYTCVAENEVGQVQSAARLHIT 2390



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 48/178 (26%), Positives = 74/178 (41%), Gaps = 16/178 (8%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P F + L+N   +S G  I LECR+   G P  +V WF + + +   SRF      G V
Sbjct: 2395 QPKFAERLTNVS-ISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDV 2451

Query: 1236 -ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER-------SDIVTDTQNEQAIEQ 1287
              L I   T  D G Y   A N  G   T A + V +R        ++V     E   E+
Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGNPPFFVKELVDIDVTEGGHER 2511

Query: 1288 IQLLEDAARRTK--QVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMR 1343
             +++ D   + +    + DI +   P+F    H       T +  +CR +  G  T +
Sbjct: 2512 FEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHG---DHHTLIVKDCRPEETGKLTCK 2566



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G  P F+  L  ++ + EG    FE  V+    P   IDW+ N   IR G ++       
Sbjct: 2490 GNPPFFVKELVDID-VTEGGHERFEVVVDGYPKPE--IDWYKNDILIRPGPKFDIKEHGD 2546

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +  L +     E++G   CKA N  G+A+ +C +++
Sbjct: 2547 HHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQI 2582



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 3951 KKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWF 4010
            K    EV  T + L + +  +PP+F+ +  S   ++E +  KFE +++  G P  +VEW 
Sbjct: 3039 KNKVGEVSCTAELLVE-EGMRPPQFIVK-PSSLQIMEGKMAKFEARVS--GLPGPEVEWL 3094

Query: 4011 FNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057
             +G+P+    RF   ++     +        D GEY C AT+  G D
Sbjct: 3095 RDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKD 3141



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/85 (30%), Positives = 47/85 (55%), Gaps = 3/85 (3%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            PE++  I+   +L EG++   + ++     P+  + WY +   +E G RF++ SD    +
Sbjct: 3156 PEFVRKIS-NIELTEGEIARFDVRITGTPAPE--VTWYKDEVPIEDGGRFEIYSDDDKHS 3212

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEA 2995
            L + D    D+G Y+CKA N+ G+A
Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQA 3237



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            PT   EG    +E  +   P P+  VEW+ +   +     Y         +L I  V  +
Sbjct: 3262 PTDFEEGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPD 3319

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            DSG YTC A N  G A  +  +++++ E
Sbjct: 3320 DSGAYTCTATNECGMAKRTYNIDIEASE 3347



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 2/84 (2%)

Query: 781  ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
            + +EG +  FEA ++    P   VEW+KD  PI+ SS      +    SL I  +  +D+
Sbjct: 3264 DFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDS 3321

Query: 841  GSYTVRAVNKLGEAISTASIRVAA 864
            G+YT  A N+ G A  T +I + A
Sbjct: 3322 GAYTCTATNECGMAKRTYNIDIEA 3345



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  +  EA V  R  P+  +EW K+   ++  +           +L+I  +  DDSG Y
Sbjct: 3267 EGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAY 3324

Query: 2716 TCKATNLLGEAVSTASIKIE 2735
            TC ATN  G A  T +I IE
Sbjct: 3325 TCTATNECGMAKRTYNIDIE 3344



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 38/132 (28%), Positives = 57/132 (43%), Gaps = 10/132 (7%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V +EGD    +  V+ +  P   +EW  +++P+ S +  K T +    SL I    + D 
Sbjct: 4861 VTEEGD---IKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDE 4917

Query: 2844 GIYTCKATNSKGSATTSGSLRCTGDKNIYFD-TQHPQ--GKAGLEAVEQAEEARLAKGRR 2900
            G+YT K TN  GS T +  ++        F+ T  P+          E  EE  +    R
Sbjct: 4918 GMYTVKITNDVGSGTRTFDVKVEDTTTSLFEGTVRPKFIEDDSFVPFESTEEGNV----R 4973

Query: 2901 PSVPDTEYPKPE 2912
             SV  T  P PE
Sbjct: 4974 LSVKITGKPVPE 4985



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 51/185 (27%), Positives = 81/185 (43%), Gaps = 16/185 (8%)

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAG---EYSVKAINALGHCTSAISMTVTAKGS 2339
            +A+ +A R     D    S D +   PED     E S K I A+G    A+++T+  K  
Sbjct: 2106 EAVNNAGRASTEADILVESAD-EGSEPEDEPQQMEQSTKTI-AIGQEPPAVTLTLDGKAG 2163

Query: 2340 I---ISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHF 2396
                  E + P   E   E    +  +   +P+P+    P F   L++I+ + EG T   
Sbjct: 2164 FDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIP---PEFKSALRDIE-VNEGNTVTL 2219

Query: 2397 DCRLIPVGDPTLKVEWFRNEKLIED-SSRITKTHDFGYV-SMTISHVRDEDEGVYMCRAS 2454
              R+   G P  +V+WF++ K +     R  +    G V ++ I   R  D G Y+C+A 
Sbjct: 2220 --RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAY 2277

Query: 2455 NLLGE 2459
            N  GE
Sbjct: 2278 NSAGE 2282



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 3/104 (2%)

Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022
            D+  V  K+PP+F   ++  T + E  +T+F+ Q+   G P  KV W+ NGK +  ++  
Sbjct: 2290 DVLHVAPKEPPKFERNLKDIT-IAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHV 2346

Query: 4023 TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
              ++D  + ++       + SG+Y C A N  G  ++ A +  T
Sbjct: 2347 DIVHDDEHSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHIT 2390



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F K + + +VTEG     E  +     P   ++WY N   ++ G +F       +  L
Sbjct: 2493 PFFVKELVDIDVTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEHGDHHTL 2550

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
             +     E+TG   CKA N+ G+A+ +  V+++ K+
Sbjct: 2551 IVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKT 2586



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 9/125 (7%)

Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295
            E  + PP+F+ +   +  + EGK A FE +V  +  P   +E+  +G+ ++   RF I F
Sbjct: 3054 EEGMRPPQFIVK-PSSLQIMEGKMAKFEARVSGLPGPE--VEWLRDGRPIKPGRRFQIEF 3110

Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRE 2355
            +     L I      D GEY+  A +  G  + ++ + V    +++     PE + KI  
Sbjct: 3111 EKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDE--AVVP----PEFVRKISN 3164

Query: 2356 LESAE 2360
            +E  E
Sbjct: 3165 IELTE 3169



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 15/132 (11%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845
            +EG +I FE  V  S  P   +EW  +  P+   + Y         SL I     +DSG 
Sbjct: 3266 EEGGDITFEATV--SGRPRPDVEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGA 3323

Query: 2846 YTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPD 2905
            YTC ATN  G A  +         NI  +   P+G    + ++  +   + +G+  +   
Sbjct: 3324 YTCTATNECGMAKRT--------YNIDIEASEPKGSTP-QFIDLMQPVEVTEGQTATFEC 3374

Query: 2906 T--EYPKP--EW 2913
            T   YP+P  EW
Sbjct: 3375 TVKGYPRPSIEW 3386



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 57   DRQPIT-AGRPGEPSPPIFEQIFKNA-RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVE 114
            D +P T A  P E   P + +    A +    G+ K   ++RG P P V WT+   P+V 
Sbjct: 4167 DLRPHTFAYEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRVRGKPKPTVKWTKNDEPVVP 4226

Query: 115  CNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
             + +S+   +     SLLI++    D+G Y   A N+ G
Sbjct: 4227 SSHFSVLMEDDV--FSLLIRKPSKTDKGVYKVIATNEGG 4263



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 59/245 (24%), Positives = 100/245 (40%), Gaps = 41/245 (16%)

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852
            F+ +V+ +  P   ++W  + +PL  G  +K+        L I     ED G Y C+A N
Sbjct: 2050 FKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVN 2109

Query: 2853 SKG-SATTSGSLRCTGD----------------KNIYFDTQHP------QGKAGLE--AV 2887
            + G ++T +  L  + D                K I    + P       GKAG +  AV
Sbjct: 2110 NAGRASTEADILVESADEGSEPEDEPQQMEQSTKTIAIGQEPPAVTLTLDGKAGFDFQAV 2169

Query: 2888 E---------QAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPK 2938
            E           E+ R+   +  ++P    P P        + ++ EG  + L  ++   
Sbjct: 2170 ELKIPHPDEIAEEDLRIDVEQTAALPK---PIPPEFKSALRDIEVNEGNTVTL--RIHVT 2224

Query: 2939 NDPDLKIEWYFNGKVLE--QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAF 2996
              P  +++W+ +GK +      RF++       TL + +    D+G Y CKAYN  GE  
Sbjct: 2225 GSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVT 2284

Query: 2997 TSSTV 3001
            +S  V
Sbjct: 2285 SSCNV 2289



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS- 695
            P+F   L +V+   G  I  E R+   G P  ++ W K+ + I   SRF+   R G +  
Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCV 2453

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L +  +   D G Y C A +  G  +T A L V  R
Sbjct: 2454 LTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKR 2489



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 39/150 (26%), Positives = 71/150 (47%), Gaps = 16/150 (10%)

Query: 3231 GEDFTRATINCYGKGGVYLESLQ-----PDSLAKIRELESLQGAQQQTPSTPSAEPPKFI 3285
            G++    T+   GK G   ++++     PD +A+    E L+   +QT + P   PP+F 
Sbjct: 2148 GQEPPAVTLTLDGKAGFDFQAVELKIPHPDEIAE----EDLRIDVEQTAALPKPIPPEFK 2203

Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKK---LPHGHRYRTFHDFGIVIL 3342
            + ++D+ ++ EG +     R+     P  +V+WF +GK    LPH  R+       +  L
Sbjct: 2204 SALRDI-EVNEGNTV--TLRIHVTGSPKPEVDWFKDGKPVSGLPH-RRFEVGCVGEVYTL 2259

Query: 3343 DILYCYEENSGEYECVATNKLGRDSTKANL 3372
             I      ++G+Y C A N  G  ++  N+
Sbjct: 2260 VIKEARGSDTGKYLCKAYNSAGEVTSSCNV 2289



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 4/100 (4%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR-TTHDFGY 2166
            +P F   LT++ ++  GD    ECRV     P   + WF + ++IR   R+   T     
Sbjct: 2395 QPKFAERLTNV-SISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDV 2451

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRN 2206
              L I     +D G+Y C ATN  G+      L VA   N
Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV- 3478
            P F   L+N+ ++  G+    E R+T    P  +V W+ + K ++  SRF      G V 
Sbjct: 2396 PKFAERLTNV-SISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDVC 2452

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
            +L I    P+D G Y C A N  G+  T A + V  + N
Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 28/106 (26%), Positives = 54/106 (50%), Gaps = 4/106 (3%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+ V+ G++  P F     S  +++EG+    EA+V     P  ++EW ++G  +  G R
Sbjct: 3050 ELLVEEGMRP-PQFIVKPSSL-QIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRR 3105

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             +  F+     L+I   + +D G YTC AT+  G+   +  + +++
Sbjct: 3106 FQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDE 3151



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            +I+EG+ A FEARV         VEW  +G+ I    R Q   +     L I   +  D 
Sbjct: 3070 QIMEGKMAKFEARVSGLPG--PEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDE 3127

Query: 1114 GVYTVVARNAAGEAQLSASMTVE 1136
            G YT VA + AG+   S  + V+
Sbjct: 3128 GEYTCVATSKAGKDSCSVELLVD 3150



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 2/68 (2%)

Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            E +V+E  A  PP FV     + + EGE ARF  R+TG P P V W  +   I +G R++
Sbjct: 3146 ELLVDE--AVVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFE 3203

Query: 4159 LTYDGMYH 4166
            +  D   H
Sbjct: 3204 IYSDDDKH 3211



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)

Query: 3276 TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH 3335
            T  A  PKF  ++ +V+ +  G +   E R+     P  +V WF + K++    R+    
Sbjct: 2390 TELAIQPKFAERLTNVS-ISSGDTIVLECRVTGKPRP--QVAWFKDDKEIRQDSRFSFET 2446

Query: 3336 DFG-IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379
              G + +L I     ++ G Y+C+ATN  G+D T A L    + N
Sbjct: 2447 RPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 59/253 (23%), Positives = 103/253 (40%), Gaps = 36/253 (14%)

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            LTI+  + +D G Y C   +  G++T + N+ I +     A+  +P    K++   +   
Sbjct: 4755 LTIREPSPNDTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYP----KVEPFHEKP- 4809

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEG-------QSAHFEA-RVEP-----QSDLTM 1075
             S+ T    KI Q  + L P +    I+E        +    E   V+P     + D+ M
Sbjct: 4810 LSEETMSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKM 4869

Query: 1076 TV----------EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAG 1125
            TV          EW  + + + S + I+   +    +L I      D G+YTV   N  G
Sbjct: 4870 TVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG 4929

Query: 1126 EAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEE--ISKSKPVFVQPL 1183
                S + T + +    T+S+  G   + + IE+  FV P    EE  +  S  +  +P+
Sbjct: 4930 ----SGTRTFDVKVEDTTTSLFEGTV-RPKFIEDDSFV-PFESTEEGNVRLSVKITGKPV 4983

Query: 1184 SNPPPVSEGKNIH 1196
                   + K +H
Sbjct: 4984 PEVSWTKDEKPVH 4996



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 56/228 (24%), Positives = 91/228 (39%), Gaps = 41/228 (17%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            D++  +    P+F    K I  + EG    F+ ++    +   KV W+ NG+ V      
Sbjct: 2290 DVLHVAPKEPPKFERNLKDI-TIAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHV 2346

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLE 1553
              +HD  + +L ++    + SG YTC A                         +NE G  
Sbjct: 2347 DIVHDDEHSSLILMHCPLDLSGKYTCVA-------------------------ENEVG-- 2379

Query: 1554 QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEW 1613
            Q+Q     ++ H T++  +     P     L NV I  G     E R+        +V W
Sbjct: 2380 QVQ---SAARLHITELAIQ-----PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAW 2429

Query: 1614 YHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            + ++K ++  SRF+ ET       L I    P+D G+Y C A N  G+
Sbjct: 2430 FKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQ 2477



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P FV+ +SN   ++EG+    + R+   G P   V W+ +   +  G RF+ Y D    +
Sbjct: 3156 PEFVRKISNIE-LTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHS 3212

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSA 1261
            L I     +DTG Y+ +A N  G A
Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQA 3237



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 38/171 (22%), Positives = 62/171 (36%), Gaps = 7/171 (4%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE-- 3133
            G     + W  + K I  +  I+         L I      D G Y C A+N  G +   
Sbjct: 4526 GKPKPTVTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGIYKCTASNSVGTSSQM 4585

Query: 3134 ISVKLECVD---KSKGQK-PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189
              V ++  D   KSK    P F     ++E  +         TV+    P  +++W  + 
Sbjct: 4586 FDVDIKGTDWMLKSKDDDFPSFVDE-DDVEAFEMTDEGSIRMTVIVRGKPKPEVKWSKDD 4644

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
            +P+  ++ I          L I    + D G Y C A N+ G +     +N
Sbjct: 4645 KPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVNRAGTNIRSFVVN 4695



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 36/150 (24%), Positives = 65/150 (43%), Gaps = 5/150 (3%)

Query: 1123 AAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQP 1182
            A G+   + ++T++ ++  D  ++   +       EE   ++ + Q   + K  P   + 
Sbjct: 2146 AIGQEPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRID-VEQTAALPKPIPPEFKS 2204

Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT--VGSRFKTYYDFGFVALDII 1240
                  V+EG  + L  R+   G P   V+WF +G+ V+     RF+         L I 
Sbjct: 2205 ALRDIEVNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIK 2262

Query: 1241 HATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
             A  +DTG+Y  +A N  G   +S  V V+
Sbjct: 2263 EARGSDTGKYLCKAYNSAGEVTSSCNVDVL 2292



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLD 2834
            F   L N+    GD I  EC V  +  P  ++ WF ++K +   +R+   T       L 
Sbjct: 2398 FAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCVLT 2455

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I     +D G Y C ATN  G   T   L
Sbjct: 2456 IRGVTPDDEGSYKCIATNPAGQDDTVAEL 2484



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 67   GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
            G+  PP F++  K+    +G   K + K+   P   V W +   PL   + +     E+ 
Sbjct: 2028 GDIQPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFK---TERH 2084

Query: 127  GDV-SLLIKQIGPGDEGEYTCTARNQYGEA 155
            GD   L+I +    DEG Y C A N  G A
Sbjct: 2085 GDTYFLIIPEADVEDEGRYRCEAVNNAGRA 2114



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 3/118 (2%)

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            +G + PP   +  ++ +++EG   +  V+++  P   V W K+G+ L     H     H 
Sbjct: 2027 MGDIQPPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPL-KPGDHFKTERHG 2085

Query: 320  HT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-SYVQDQRSQYITDTQ 375
             T  L +      D G Y   A N  G   T   + VES  E S  +D+  Q    T+
Sbjct: 2086 DTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQSTK 2143



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 3/97 (3%)

Query: 2105 PGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF 2164
            P + P F   L  +  + EG    F+ +V     P   + W+HNG+ ++        HD 
Sbjct: 2296 PKEPPKFERNLKDI-TIAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDD 2352

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             + +L +++   + SG Y C A N++G+  +   L +
Sbjct: 2353 EHSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 3/95 (3%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P+F+  +KD I+I EG    F+ ++   G    +V W  +G+ V+    +    +  +
Sbjct: 2298 EPPKFERNLKD-ITIAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDDEH 2354

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +L +    +  +G YTC A N +GQ  ++A L I
Sbjct: 2355 SSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+F   +  N+ +  G  +  +CRV   G P  ++ WF + +     SR       G + 
Sbjct: 2396 PKFAERLT-NVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVC 2452

Query: 3755 -LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791
             L I  +   D G Y C ATN  G   T A++T  AKR
Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTV-AKR 2489



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+ VD  V   P F   + + + L EG+    + ++     P  ++ W+K+ V +  G R
Sbjct: 3146 ELLVDEAVVP-PEFVRKISNIE-LTEGEIARFDVRITGTPAP--EVTWYKDEVPIEDGGR 3201

Query: 2691 LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
             +   D    +L I      D+G Y+CKATN  G+A
Sbjct: 3202 FEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA 3237



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 1311 PQFSRALHNIET--VEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            P F+     I T   EG ++  E  +   G     VEW  +  PI     +      D  
Sbjct: 3252 PHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDTY 3309

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEA 1394
            +L +  V P+DSG YTC ATN+ G A
Sbjct: 3310 SLTIRGVGPDDSGAYTCTATNECGMA 3335



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 23/64 (35%), Positives = 33/64 (51%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  +I+WFK+G  L+    +K T D  L T+ I      D+G Y C   N+ G+A  T  
Sbjct: 3994 PFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGKATRTFD 4053

Query: 2732 IKIE 2735
            + IE
Sbjct: 4054 VDIE 4057



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 67/331 (20%), Positives = 122/331 (36%), Gaps = 41/331 (12%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA--EISVKLE 3139
            I+WF +G+ +     I+      +  + I      D+G Y C   N  G+A     V +E
Sbjct: 3998 IDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGKATRTFDVDIE 4057

Query: 3140 CVDKSKGQKPRFTTH--------IQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
             V  S+  +   + H        +  +   +      F  TV      D  ++W  +G+ 
Sbjct: 4058 AVKPSRHVRGELSEHLILPKFIDVTEVSPYRVSYDGDFTLTVKLSGSGD--VQWMKDGEV 4115

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251
            +  S R     D    +L I      D G Y C   NK G D TR+         + LE 
Sbjct: 4116 IEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAGFD-TRSF-------DIGLED 4167

Query: 3252 LQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDD 3311
            L+P + A               PS   A  P ++       ++ +        R+     
Sbjct: 4168 LRPHTFA-------------YEPSELVA--PYYLEDGVTAFQMTDAGDVKLTVRVRGKPK 4212

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P +K  W  N + +     +    +  +  L I    + + G Y+ +ATN+ G ++ + N
Sbjct: 4213 PTVK--WTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGGINTKRFN 4270

Query: 3372 LKC----TSKENLILDSQLPRGMEGGLEKLQ 3398
            +      T+   ++ D + PR ++ G+   +
Sbjct: 4271 VDIEWDETTTTRVVDDREAPRFLDDGISSYE 4301



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 46/195 (23%), Positives = 78/195 (40%), Gaps = 8/195 (4%)

Query: 3054 FKDIVDISEGQIAHY-EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILG 3112
            F D+ ++S  ++++  + +L      S  ++W  +G+ IE S R        + +L ILG
Sbjct: 4078 FIDVTEVSPYRVSYDGDFTLTVKLSGSGDVQWMKDGEVIEDSKRYVIRQDDDLHMLTILG 4137

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA----- 3167
                D GTY C  TNK G    S  +   D          + +     L+DG +A     
Sbjct: 4138 ATEDDLGTYKCVVTNKAGFDTRSFDIGLEDLRPHTFAYEPSELVAPYYLEDGVTAFQMTD 4197

Query: 3168 --HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                + TV     P   ++W  N +P+  S+    + +     L I      D G Y   
Sbjct: 4198 AGDVKLTVRVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVI 4257

Query: 3226 AYNKYGEDFTRATIN 3240
            A N+ G +  R  ++
Sbjct: 4258 ATNEGGINTKRFNVD 4272



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 46/198 (23%), Positives = 74/198 (37%), Gaps = 29/198 (14%)

Query: 1478 VEWFKNGQPVT-IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            V W K+ +P+T   H    ++D  Y  + I     +D GIY C A N VGT      +  
Sbjct: 4532 VTWTKDSKPITETDHIQVSVYDDTYTLI-IKSPTDKDEGIYKCTASNSVGTSSQMFDVDI 4590

Query: 1537 RSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
            + T  +++S  ++          D       +M DE + +  +        E+K      
Sbjct: 4591 KGTDWMLKSKDDD-----FPSFVDEDDVEAFEMTDEGSIRMTVIVRGKPKPEVK------ 4639

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAIN 1656
                            W  ++KPL   S            L I S   +D GTY C A+N
Sbjct: 4640 ----------------WSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVN 4683

Query: 1657 ALGEAVTSGIAIVHSKKS 1674
              G  + S +  V+++ S
Sbjct: 4684 RAGTNIRSFVVNVNTEDS 4701



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 43/178 (24%), Positives = 70/178 (39%), Gaps = 18/178 (10%)

Query: 2572 SVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPE 2631
            +V     G+ MC AI                   ++D+  RP  ++ ++L+    ++  E
Sbjct: 1950 TVGGGPGGIEMCVAIQDFEDEFGDFSLKKKESVIVLDKISRPGMYKVVRLRSDG-SRGDE 2008

Query: 2632 MFVDTGVQQA--------------PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIE 2677
            M+V   V Q               P F   LK  + + EG+   L+ ++    + N+K  
Sbjct: 2009 MWVPPNVLQKKRSTAEIMMGDIQPPFFQKPLKDKE-VKEGKPFKLDVKITALPEANVK-- 2065

Query: 2678 WFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            W K+G  L  G   K+        L I     +D G Y C+A N  G A + A I +E
Sbjct: 2066 WLKDGEPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVE 2123



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 35/148 (23%), Positives = 61/148 (41%), Gaps = 5/148 (3%)

Query: 1791 LGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQL 1850
            +G+   + TL +  KA    ++         +  E+  R    +   +     P F + L
Sbjct: 2147 IGQEPPAVTLTLDGKAGFDFQAVELKIPHPDEIAEEDLRIDVEQTAALPKPIPPEFKSAL 2206

Query: 1851 NGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS-GHRYRTSNDFGFA-ALDILT 1908
                +++EG +      +   P P   V+W+ +GK +    HR       G    L I  
Sbjct: 2207 RD-IEVNEGNTVTLRIHVTGSPKPE--VDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKE 2263

Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
              G D+G+Y CKA N+ G+  SS  ++V
Sbjct: 2264 ARGSDTGKYLCKAYNSAGEVTSSCNVDV 2291



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 3/110 (2%)

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
            G   TV  LT  A+ GNPP F     D+ ++E     FE  ++        ++W+ N   
Sbjct: 2476 GQDDTVAELTV-AKRGNPPFFVKELVDIDVTEGGHERFE--VVVDGYPKPEIDWYKNDIL 2532

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +  G +           L +      + G  TCKA N  G+A  SC +Q+
Sbjct: 2533 IRPGPKFDIKEHGDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQI 2582



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 3/101 (2%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474
            ++G  P F   L +I+ + EG +  FE  +     P  +++WY N   ++ G +F     
Sbjct: 2488 KRGNPPFFVKELVDID-VTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEH 2544

Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
                 L +    PE++G+  C+A N+ G+A+ +  +++  K
Sbjct: 2545 GDHHTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 1/101 (0%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P F K  +D++V EGK  + D ++T  P   V W + D +     +H         + L+
Sbjct: 2033 PFFQKPLKDKEVKEGKPFKLDVKITALPEANVKW-LKDGEPLKPGDHFKTERHGDTYFLI 2091

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPK 492
            I    + D G   C A N +G  + +  + V   ++   P+
Sbjct: 2092 IPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPE 2132



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 6/103 (5%)

Query: 2920 EHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLT--SDFGFVTLDLVDVY 2977
            + ++ EG+   L+ ++     P+  ++W  +G+ L+ G  FK     D  F+ +   DV 
Sbjct: 2041 DKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTYFLIIPEADV- 2097

Query: 2978 ERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTE 3020
              D G Y C+A N  G A T + +   S D   E    P+  E
Sbjct: 2098 -EDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQME 2139



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP+F     D+ ++E  S  F+ ++        +V W+HNGK +     V  ++D     
Sbjct: 2299 PPKFERNLKDITIAEGCSTRFDVQV--TGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSS 2356

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L +       +G YTC A N  G+   + +L +
Sbjct: 2357 LILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 2/104 (1%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F+  L  +   EGG   FE  ++  G P  +I+W KN   I    +F       + +
Sbjct: 2492 PPFFVKELVDIDVTEGGHERFEVVVD--GYPKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQ 739
            L +     +++G+ TC+A ++ G A     + +  +    + +Q
Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTIPPKITQ 2593



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDI 4169
            PP FV     + V EG   RF   V G+PKP + W  N   I  G ++ +   G +H  I
Sbjct: 2492 PPFFVKELVDIDVTEGGHERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTLI 2551

Query: 4170 PK-TRQYDTGKI 4180
             K  R  +TGK+
Sbjct: 2552 VKDCRPEETGKL 2563



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 1586 NVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPE 1645
            +++I EG+ A FE R+  +     +VEW  + +P+K G RF          L I+     
Sbjct: 3068 SLQIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLN 3125

Query: 1646 DSGTYTCRAINALGE 1660
            D G YTC A +  G+
Sbjct: 3126 DEGEYTCVATSKAGK 3140



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 4/102 (3%)

Query: 1972 SFVVEKPQFGK--PIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            +F+   P F +  P    +  EG  +  EAT++    P   VEW+ +  P+ +   +   
Sbjct: 3246 TFIPVPPHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLH 3303

Query: 2030 YDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
                  +L I     +D+G Y C ATN  G A  T ++ ++A
Sbjct: 3304 RSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRTYNIDIEA 3345



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 83/347 (23%), Positives = 131/347 (37%), Gaps = 51/347 (14%)

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
            GP  ++E      E +I+  P P++R  WY +   L    R +   +     + I     
Sbjct: 3754 GPLSITEDGDLVLEVKIKGEPLPDVR--WYKDDVPLDETCRIKIDAEGDIQIVTIKDANK 3811

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDD 1971
            EDS  +T    N+ G A+    ++V            ES + K+Q        KR   D+
Sbjct: 3812 EDS-VFT-NITNDFGTAIRRFSIDV------------ESVMPKLQGF-----VKR---DE 3849

Query: 1972 SFVVEKPQFG--KPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
             F    PQF   + +   EVT    + L+  +T   +P   V W+ +G PV         
Sbjct: 3850 DF----PQFVNVEGVSPFEVTSEGDIKLQTRVTGFPEPD--VSWFKDGIPVVPNEHIVYH 3903

Query: 2030 YDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQ 2089
                   L I        GTY C ATN  G    +   +V  ++G   + +        Q
Sbjct: 3904 IRDDVHILIIKSPTPLYAGTYKCVATNRRG--TNSRDFEVTIETGEAAEHIT------FQ 3955

Query: 2090 ELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNG 2149
            + E+  R + IE+      P  +T        +EGD    + +V     P   IDWF +G
Sbjct: 3956 QDEETVRAQFIEKGPYAPVPFEIT--------EEGD---VKLQVRICGIPFPEIDWFKDG 4004

Query: 2150 QKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNT 2196
            + +      + T D     + I     +D+G Y C   N  G+A  T
Sbjct: 4005 RHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGKATRT 4051



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 2/75 (2%)

Query: 87   GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146
            G+ +    +RG P P V W++   PL   +   M   + T   +L+IK     D G Y C
Sbjct: 4622 GSIRMTVIVRGKPKPEVKWSKDDKPLTPNSNIVMEEMDDT--YTLVIKSPSSDDRGTYKC 4679

Query: 147  TARNQYGEAICSVYI 161
            TA N+ G  I S  +
Sbjct: 4680 TAVNRAGTNIRSFVV 4694



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 40/145 (27%), Positives = 61/145 (42%), Gaps = 9/145 (6%)

Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTT--GKPGIVYDSQLPKHMKSIEKIREMEASWQVT 4097
            PED  + + ++T    + +    +  T  GK G  +D Q  + +K        E   ++ 
Sbjct: 2131 PEDEPQQMEQSTKTIAIGQEPPAVTLTLDGKAG--FDFQAVE-LKIPHPDEIAEEDLRID 2187

Query: 4098 PEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGS 4155
             EQ     K   PP F S    + V EG        VTG PKP V W  +G  +  +   
Sbjct: 2188 VEQTAALPKP-IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHR 2246

Query: 4156 RYKLTYDG-MYHFDIPKTRQYDTGK 4179
            R+++   G +Y   I + R  DTGK
Sbjct: 2247 RFEVGCVGEVYTLVIKEARGSDTGK 2271



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 9/97 (9%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV- 2700
            P F + L+  + + EG  V L   V     P  +++WFK+G  ++     +  F+ G V 
Sbjct: 2200 PEFKSALRDIE-VNEGNTVTLRIHVTGSPKP--EVDWFKDGKPVSGLPHRR--FEVGCVG 2254

Query: 2701 ---TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
               TL I   R  D+G Y CKA N  GE  S+ ++ +
Sbjct: 2255 EVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDV 2291



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 43/168 (25%), Positives = 72/168 (42%), Gaps = 5/168 (2%)

Query: 2240 SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGY 2299
            +PP FV EL     V EG    FE  V+    P   I++Y N   ++   +F I     +
Sbjct: 2491 NPPFFVKELVDID-VTEGGHERFEVVVDGYPKPE--IDWYKNDILIRPGPKFDIKEHGDH 2547

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESA 2359
             +L ++ C PE+ G+ + KA N+ G    +  + +  K      +QR   L         
Sbjct: 2548 HTLIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTIPPKITQRLHDLSIDAGKTVN 2607

Query: 2360 EPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPT 2407
               K    PEP+ +   +  + + N D + + +T+H    L+ VG  T
Sbjct: 2608 LTVKFFGTPEPLVKWF-MDDEEITNEDGV-DIETSHCTSSLVLVGVDT 2653



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 7/124 (5%)

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            V+W  +G+ I+   R+    + D   L +L    +D G Y C  TN+ G    S  + + 
Sbjct: 4107 VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAGFDTRSFDIGLE 4166

Query: 1404 AKKDLILESQHPSGLEKIQYLED-TSRYKKTDIIDESVTIKPRFVTRP-----KSIENVI 1457
              +     +  PS L    YLED  + ++ TD  D  +T++ R   +P     K+ E V+
Sbjct: 4167 DLRPHTF-AYEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRVRGKPKPTVKWTKNDEPVV 4225

Query: 1458 EGQH 1461
               H
Sbjct: 4226 PSSH 4229



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 77/356 (21%), Positives = 136/356 (38%), Gaps = 46/356 (12%)

Query: 1278 DTQNEQAIEQIQLLEDAARRTKQVREDITVM--QAPQFSRALHNIETVEGTNV-HLECRL 1334
            +T +   I Q +   + AR  K + ED+     Q P F      ++  E T    ++  +
Sbjct: 4813 ETMSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIET-DEVKPFEVTEEGDIKMTV 4871

Query: 1335 QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEA 1394
            +  G     VEW  + +P+ +    +   E D  +L +      D G+YT + TN +G  
Sbjct: 4872 KVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSG 4931

Query: 1395 VTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSI- 1453
              +  ++V                      EDT+    T + +   T++P+F+     + 
Sbjct: 4932 TRTFDVKV----------------------EDTT----TSLFEG--TVRPKFIEDDSFVP 4963

Query: 1454 -ENVIEGQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLI 1510
             E+  EG +V    K+  +PV +    V W K+ +PV      R  H      L I +  
Sbjct: 4964 FESTEEG-NVRLSVKITGKPVPE----VSWTKDEKPVHKIQNIRLDHQDDIYTLTIREAT 5018

Query: 1511 AEDSGIYTCRAVNLVG--TDEVSCRLTCRSTTDIVRSTQNEA-GLEQIQVLEDRSKYHRT 1567
              DSG Y C   N  G  T   S  +   +  +  + T+ E   LE+ ++          
Sbjct: 5019 PNDSGSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEV 5078

Query: 1568 DMVDEVTTQAPICTTSLKNVEIK--EGQRAHFERRLIPVSDATLKVEWYHNNKPLK 1621
              + E  T+  I    +K  + K  E +   FE + +   +  +  E     KPL+
Sbjct: 5079 KPLVETITRKEIKVEEVKPKKGKPTEREAKPFEEKPLIEEELPISAEKVVEEKPLE 5134



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 42/195 (21%), Positives = 71/195 (36%), Gaps = 28/195 (14%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            VEW  +++P+ S S    T      +L I      D G YT +  N +G    SG     
Sbjct: 4881 VEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG----SGTRTFD 4936

Query: 1671 SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHF 1730
             K      S  EG + R   +ED S     S ++  +  +   T                
Sbjct: 4937 VKVEDTTTSLFEGTV-RPKFIEDDSFVPFESTEEGNVRLSVKIT---------------- 4979

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
                   G P   V W ++  P+     +   H      L ++   P DSG+Y C   N+
Sbjct: 4980 -------GKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTND 5032

Query: 1791 LGEAVTSSTLFVQSK 1805
             G++  + ++ ++ +
Sbjct: 5033 AGKSTRTFSVEIEGE 5047



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 49/181 (27%), Positives = 71/181 (39%), Gaps = 20/181 (11%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV-I 3616
            P+F    +++ +S   +   ECR+        +V WF + K +   SR       G V +
Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCV 2453

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I GV   D G Y C ATN  G+     +L V  R         P  F      I  + 
Sbjct: 2454 LTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN-------PPFFVKELVDID-VT 2505

Query: 3677 ETLHKREEITIED-EKPNPPRFTVEI----KDNIDVPEGGPVHF----DCRVEPVGDPTM 3727
            E  H+R E+ ++   KP    +  +I        D+ E G  H     DCR E  G  T 
Sbjct: 2506 EGGHERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHTLIVKDCRPEETGKLTC 2565

Query: 3728 R 3728
            +
Sbjct: 2566 K 2566



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 27/220 (12%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576
            P E+ E      + R+  +  P +  +W+ +G  L      + T D    T+ I      
Sbjct: 3975 PFEITEEGDVKLQVRICGIPFPEI--DWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIK 4032

Query: 2577 DAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDT 2636
            D G Y C   N AG                  +A++P    + +L E  +  +P+ F+D 
Sbjct: 4033 DTGKYKCIIKNIAGKATRTFDVDI--------EAVKPSRHVRGELSEHLI--LPK-FIDV 4081

Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
                     T +  Y    +G    L  ++    D    ++W K+G  +    R     D
Sbjct: 4082 ---------TEVSPYRVSYDGDFT-LTVKLSGSGD----VQWMKDGEVIEDSKRYVIRQD 4127

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              L  L+I     DD G Y C  TN  G    +  I +ED
Sbjct: 4128 DDLHMLTILGATEDDLGTYKCVVTNKAGFDTRSFDIGLED 4167



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P F   L   E +KEG     + ++  +  P   + W  +G+ ++ G  ++T      
Sbjct: 2031 QPPFFQKPLKDKE-VKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEA 2193
              L I     ED G Y C+A N  G A
Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRA 2114



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 5/95 (5%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT-IGHRFRPIHDFG 1500
            I P F +  + IE V EG  V    ++        +V+WFK+G+PV+ + HR   +   G
Sbjct: 2198 IPPEFKSALRDIE-VNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVG 2254

Query: 1501 YV-ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
             V  L I +    D+G Y C+A N  G    SC +
Sbjct: 2255 EVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNV 2289



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K  P F + L +   ++EG +   + ++   G P  +V W+HNG+ V         +D  
Sbjct: 2297 KEPPKFERNLKDIT-IAEGCSTRFDVQVT--GSPEPKVFWYHNGKLVQPRDHVDIVHDDE 2353

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
              +L ++H     +G+YT  A N +G   ++A + + E
Sbjct: 2354 HSSLILMHCPLDLSGKYTCVAENEVGQVQSAARLHITE 2391



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/98 (25%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA- 1769
            P F   + ++ ++       E R+   G P+ +V W ++   I   +R +     G V  
Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRPGDVCV 2453

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            L ++ V P+D G+Y C A N  G+  T + L V  + +
Sbjct: 2454 LTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFG-FA 1902
            P+F  +L     +S G +   ECR+   P P  +V W+ + K ++   R+      G   
Sbjct: 2396 PKFAERLTN-VSISSGDTIVLECRVTGKPRP--QVAWFKDDKEIRQDSRFSFETRPGDVC 2452

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
             L I  V  +D G Y C A N  GQ  +   L V  +
Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKR 2489



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            P + +    +  + EG   H   +V     P  +I+WY N  ++  G +F +       T
Sbjct: 2492 PPFFVKELVDIDVTEGG--HERFEVVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            L + D    ++G  TCKA N  G+A  S  V    K
Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 6/120 (5%)

Query: 2344 SQRPEGLEKIRELESAEPFKRPE--IPEPVT---RQRPVFTQPLQNIDNIQEGQTAHFDC 2398
            S+    + KI + E A    RPE  I E V    +Q P+F +    +   +  +      
Sbjct: 4811 SEETMSVTKILQDEKALEPARPEKNIIEDVLSKPKQEPIFIET-DEVKPFEVTEEGDIKM 4869

Query: 2399 RLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             +   G P   VEW ++++ +   S I  T +    S+TI      DEG+Y  + +N +G
Sbjct: 4870 TVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG 4929



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 3/124 (2%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566
            +P F Q      E+ EG+    + ++  +  P    +W  +G  LK G  F+T       
Sbjct: 2031 QPPFFQKPLKDKEVKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDTY 2088

Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAM 2626
             L I      D G Y C+A+N AG                 +    P+  EQ   K  A+
Sbjct: 2089 FLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQ-STKTIAI 2147

Query: 2627 NKVP 2630
             + P
Sbjct: 2148 GQEP 2151



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 12/155 (7%)

Query: 3420 PVFTVPLSNIE-NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            P FT     I  +  EG +  FEA  T +  P   VEW+ +   +   S +         
Sbjct: 3252 PHFTEEAPKIPTDFEEGGDITFEA--TVSGRPRPDVEWHKDEAPISESSHYHLHRSNDTY 3309

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT-IDKIAA 3537
             L I    P+DSG Y C A N  G A  T         NI +E+  PKG     ID +  
Sbjct: 3310 SLTIRGVGPDDSGAYTCTATNECGMAKRT--------YNIDIEASEPKGSTPQFIDLMQP 3361

Query: 3538 LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSEN 3572
            +E   G   T     +    P      + L L EN
Sbjct: 3362 VEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKEN 3396



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            G PT  + W ++EK+I   ++   T D G  S+T+    +ED G+Y C A    G
Sbjct: 4421 GRPT--ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDG 4473



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 48/239 (20%), Positives = 89/239 (37%), Gaps = 21/239 (8%)

Query: 3014 QHPKGTEGLEKIQNLEDSLRKEPGQQP---DDDTGRPPEFTTVFKDIVDISEGQIAHYEA 3070
            Q  K  E     +N+ + +  +P Q+P   + D  +P E T          EG I   + 
Sbjct: 4822 QDEKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVT---------EEGDI---KM 4869

Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
            ++  TG     +EW  + + + +   I+      +  L I     +D G Y+ + TN  G
Sbjct: 4870 TVKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG 4929

Query: 3131 QAE--ISVKLECVDKSKGQ---KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEW 3185
                   VK+E    S  +   +P+F     +    +  +  +   +V     P  ++ W
Sbjct: 4930 SGTRTFDVKVEDTTTSLFEGTVRPKFIED-DSFVPFESTEEGNVRLSVKITGKPVPEVSW 4988

Query: 3186 YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244
              + +P+     I+         L I     +DSG Y C   N  G+     ++   G+
Sbjct: 4989 TKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGE 5047



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 4/87 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPS--GTRYKSTHDFSYVSL 2833
            F S L +I   EG+ +    +V  S  P  +++WF + KP+      R++        +L
Sbjct: 2202 FKSALRDIEVNEGNTVTLRIHVTGSPKP--EVDWFKDGKPVSGLPHRRFEVGCVGEVYTL 2259

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTS 2860
             I      D+G Y CKA NS G  T+S
Sbjct: 2260 VIKEARGSDTGKYLCKAYNSAGEVTSS 2286



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 5/112 (4%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            + R+ + E  I P +F   L   + +  G T   EC+V     P  ++ ++ + K ++  
Sbjct: 2384 AARLHITELAIQP-KFAERLTNVS-ISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQD 2439

Query: 2289 ARFHITFDFGYVS-LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGS 2339
            +RF      G V  L I+   P+D G Y   A N  G   +   +TV  +G+
Sbjct: 2440 SRFSFETRPGDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L +I   EG +  FE  V+    P  +I+W+ N+  +  G ++       + +L +
Sbjct: 2495 FVKELVDIDVTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEHGDHHTLIV 2552

Query: 2836 THTYEEDSGIYTCKATNSKGSATTS 2860
                 E++G  TCKA NS G A  S
Sbjct: 2553 KDCRPEETGKLTCKARNSAGQAICS 2577



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F+  +    ++ EG+ A F+ R+       +T  WY +   I    R + Y D    +
Sbjct: 3156 PEFVRKISNI-ELTEGEIARFDVRITGTPAPEVT--WYKDEVPIEDGGRFEIYSDDDKHS 3212

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            L I      D+G Y+  A N AG+A     +T+
Sbjct: 3213 LVIRDCALSDTGSYSCKATNEAGQASCYGELTI 3245



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI   +++   EG    FE  V     P  ++EW  + +P+  G R++   +     L I
Sbjct: 3062 FIVKPSSLQIMEGKMAKFEARVSGLPGP--EVEWLRDGRPIKPGRRFQIEFEKDRSVLTI 3119

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                  D G YTC AT+  G  + S  L
Sbjct: 3120 IDAKLNDEGEYTCVATSKAGKDSCSVEL 3147



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 3/83 (3%)

Query: 491  PKFVER-FSTL--NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST 547
            P F+++ F T    V E   V L  R  G P P + W KD   II +P   + +     T
Sbjct: 3644 PHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVHT 3703

Query: 548  LDIPRAKASDAAWYQCTAQNVAG 570
            L I      D   Y+  A N  G
Sbjct: 3704 LVINSPNQDDIGQYKVIASNHRG 3726



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 18/51 (35%), Positives = 27/51 (52%)

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            I W  + K++ Q ++F  T D G  +L +V   E D G+YTC A    G +
Sbjct: 4425 ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRS 4475



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 3147 QKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGF 3206
            Q P F   +++ E +K+G+    +  +  +  P+  ++W  +G+P++     KT      
Sbjct: 2031 QPPFFQKPLKDKE-VKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087

Query: 3207 VVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
              L I      D G Y C A N  G   T A I
Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADI 2120



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
            +P+F   L ++  +  G     E ++T    P  +V W+KD + I   SR +     G V
Sbjct: 2395 QPKFAERLTNVS-ISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDV 2451

Query: 829  S-LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
              L I  +  +D GSY   A N  G+  + A + VA R
Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKR 2489



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F+ ++    V E    RFE  V+    PK  I+WY+N  L+  G ++         +
Sbjct: 2492 PPFFVKELVDIDVTEGGHERFEVVVDGY--PKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTK--ATISCKKLPDIILQ 3930
            L +     E++G+  C+A N  G+        I+ K +P  I Q
Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTIPPKITQ 2593



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 4/105 (3%)

Query: 1709 QAPVF--TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            Q P+F  T  +K   V E        ++   G PK  VEWL++  P+ + + +    +  
Sbjct: 4846 QEPIFIETDEVKPFEVTEEGDIKMTVKV--TGKPKPSVEWLKDDRPVLSDSHIKMTEEDD 4903

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLE 1811
              +L ++     D G YT +  N++G    +  + V+   +   E
Sbjct: 4904 IYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTSLFE 4948



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKS-GSRFTETNNFGFV- 1635
            P   ++L+++E+ EG       R+        +V+W+ + KP+     R  E    G V 
Sbjct: 2200 PEFKSALRDIEVNEGNTVTL--RIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 2257

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTS-GIAIVH 1670
             L I      D+G Y C+A N+ GE  +S  + ++H
Sbjct: 2258 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLH 2293



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 18/53 (33%), Positives = 26/53 (49%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            PP F      +T+ EG   RF  +VTG P+P+V W  NG  +       + +D
Sbjct: 2299 PPKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHD 2351



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F + L +ID + EG    F+  ++  G P  +++W++N+ LI    +        + +
Sbjct: 2493 PFFVKELVDID-VTEGGHERFE--VVVDGYPKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            + +   R E+ G   C+A N  G+
Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQ 2573



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP FV +I S   L E E  +F+ ++   G P  +V W+ +  P+    RF    D    
Sbjct: 3155 PPEFVRKI-SNIELTEGEIARFDVRIT--GTPAPEVTWYKDEVPIEDGGRFEIYSDDDKH 3211

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYG 4055
            ++        D+G Y C+ATN  G
Sbjct: 3212 SLVIRDCALSDTGSYSCKATNEAG 3235



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 18/51 (35%), Positives = 25/51 (49%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            VEW+ +  P+   S +    +    +L I    P+DSG YTC A N  G A
Sbjct: 3285 VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAYTCTATNECGMA 3335



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 4/108 (3%)

Query: 1841 NQAPRFITQL--NGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND 1898
            ++ P FI +     P +++E      E R+  +P P+  V+W  + +V+ S   +  S+ 
Sbjct: 3641 DERPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPS--VQWLKDDEVIISSPHFMVSSH 3698

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS 1946
                 L I +   +D G+Y   A N+ G A  +  +NV+     +R S
Sbjct: 3699 ADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNVEGANDEMRAS 3746



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 2/89 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            +L E   V L  +V  +  P   + W K+   +T    ++ +      TL I S  + D 
Sbjct: 4511 QLTEEGDVKLMVRVAGKPKPT--VTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDE 4568

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHWLL 2741
            GIY C A+N +G +     + I+   W+L
Sbjct: 4569 GIYKCTASNSVGTSSQMFDVDIKGTDWML 4597



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 53/251 (21%), Positives = 101/251 (40%), Gaps = 22/251 (8%)

Query: 4215 RPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKN 4274
            +P   + T+ +    E +   EE   +  + V++ +P  KP   KE + E  +  K K  
Sbjct: 5096 KPKKGKPTEREAKPFEEKPLIEEELPISAEKVVEEKPLEKPIARKEKKVEKVKPKKEKPT 5155

Query: 4275 EEYYNKLQE----------LENEQVIKESRLRE--STHQYAIPGDKVTSNTVAKSMAQRY 4322
            E     L+E          +  E+V++E  L +  +  +  +   K       +  AQ  
Sbjct: 5156 EREAKPLEEKHLVEEKELPVSAEKVVEEKPLEKPITRKEDKVEEVKPKKEKPMEREAQHL 5215

Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEV--VGDKEITR 4380
            E+     E+      +K + +KP     +     G+EV   K+K T++E   + +K +  
Sbjct: 5216 EEKPLLKEKELPVSAEKAIEEKPLEKPFTPKDKKGEEVKPKKEKPTEREAKPLEEKPLVE 5275

Query: 4381 K----ITSTETTE---IEHKAQTQERVVEGPVKPSKPPIFTKKMQPCR-VFEHEQARFEV 4432
            K    +++ +  E   +E     +E+V E   K  KP +   K +  + + E ++     
Sbjct: 5276 KDELPVSAEKVVEENPLEKPITRKEKVEEVKPKKEKPTVREAKSREVKPLVEEKELPVSA 5335

Query: 4433 EFDGEPLPLIK 4443
            E   E  PL K
Sbjct: 5336 EKAVEEEPLEK 5346



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 20/70 (28%), Positives = 36/70 (51%)

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            V+    P+ K+ WY NGK+++      +  D    +L L+      SG YTC A N+ G+
Sbjct: 2321 VQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCVAENEVGQ 2380

Query: 2995 AFTSSTVYCT 3004
              +++ ++ T
Sbjct: 2381 VQSAARLHIT 2390



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 4/97 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDFGLV 2700
            P F   L +   +  G  + LE +V  +  P  ++ WFK+   +   +R    T    + 
Sbjct: 2396 PKFAERLTNVS-ISSGDTIVLECRVTGKPRP--QVAWFKDDKEIRQDSRFSFETRPGDVC 2452

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             L+I  +  DD G Y C ATN  G+  + A + +  R
Sbjct: 2453 VLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKR 2489



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEG--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            +  PP F  +      +  EG  + FE  V  +  P+  +EW+++   +     Y     
Sbjct: 3248 IPVPPHFTEEAPKIPTDFEEGGDITFEATVSGR--PRPDVEWHKDEAPISESSHYHLHRS 3305

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                SL I  V  +DSG Y C A N+ G
Sbjct: 3306 NDTYSLTIRGVGPDDSGAYTCTATNECG 3333



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            + I+P+F  R  ++ ++  G  +  EC++        +V WFK+ + +    RF      
Sbjct: 2392 LAIQPKFAERLTNV-SISSGDTIVLECRV--TGKPRPQVAWFKDDKEIRQDSRFSFETRP 2448

Query: 1500 GYVA-LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            G V  L I  +  +D G Y C A N  G D+    LT
Sbjct: 2449 GDVCVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELT 2485



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 2/87 (2%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            ++ EGQ    E  V  K  P   IEW+ NG  L++  R   T +    +L +      D 
Sbjct: 3363 EVTEGQTATFECTV--KGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDE 3420

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
            G Y C A N  G+A  ++ +     D+
Sbjct: 3421 GNYKCVARNSFGKASCATELLVDEADS 3447



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            G P   V W ++ K I ++  I    +D  Y ++ I    D+DEG+Y C ASN +G
Sbjct: 4526 GKPKPTVTWTKDSKPITETDHIQVSVYDDTY-TLIIKSPTDKDEGIYKCTASNSVG 4580



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 4/84 (4%)

Query: 72   PIFEQI--FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PIF +    K     + G+ K   K+ G P P V W +   P++  +   M   E+    
Sbjct: 4848 PIFIETDEVKPFEVTEEGDIKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKM--TEEDDIY 4905

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
            SL I++    DEG YT    N  G
Sbjct: 4906 SLTIREPTKSDEGMYTVKITNDVG 4929



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 19/73 (26%), Positives = 32/73 (43%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            +V+ +  P  ++ W  + KP+      +  H     +L I      DSG Y C  TN  G
Sbjct: 4975 SVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAG 5034

Query: 2856 SATTSGSLRCTGD 2868
             +T + S+   G+
Sbjct: 5035 KSTRTFSVEIEGE 5047



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 6/82 (7%)

Query: 1057 EGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            EG    FEA V   P+ D    VEW+ +   I+ ++    +      +L I  V  +DSG
Sbjct: 3267 EGGDITFEATVSGRPRPD----VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSG 3322

Query: 1115 VYTVVARNAAGEAQLSASMTVE 1136
             YT  A N  G A+ + ++ +E
Sbjct: 3323 AYTCTATNECGMAKRTYNIDIE 3344



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 19/62 (30%), Positives = 27/62 (43%)

Query: 2807 IEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
            I W  + K +    ++  T D    SL +    EED G+YTC A  + G +     LR  
Sbjct: 4425 ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSERRFDLRVE 4484

Query: 2867 GD 2868
             D
Sbjct: 4485 DD 4486



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 19/59 (32%), Positives = 28/59 (47%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            V W KD +P+  +  I          L IKS T  D G Y C A N++G ++   ++ I
Sbjct: 4532 VTWTKDSKPITETDHIQVSVYDDTYTLIIKSPTDKDEGIYKCTASNSVGTSSQMFDVDI 4590



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 59/306 (19%), Positives = 115/306 (37%), Gaps = 11/306 (3%)

Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTGK 4179
            + EEG   R   ++TG P P V W  +   +      +L + D +Y   I +    D+G 
Sbjct: 4966 STEEGN-VRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGS 5024

Query: 4180 IEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQ 4239
             +               +++       +G          +E       ETE+E       
Sbjct: 5025 YKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEVKPLVET 5084

Query: 4240 VLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE--LENEQVIKESRLRE 4297
            + +++  ++   E+KPK  K  E E +   ++   EE      E  +E + + K    +E
Sbjct: 5085 ITRKEIKVE---EVKPKKGKPTEREAKPFEEKPLIEEELPISAEKVVEEKPLEKPIARKE 5141

Query: 4298 STHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKP--RIPDPSESTV 4355
               +   P  +  +   AK + +++     +     E+ V++K  +KP  R  D  E   
Sbjct: 5142 KKVEKVKPKKEKPTEREAKPLEEKHLVEEKELPVSAEKVVEEKPLEKPITRKEDKVEEVK 5201

Query: 4356 HGKEVHVAKQKQ--TQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIF 4413
              KE  + ++ Q   +K ++ +KE+          +   K  T +      VKP K    
Sbjct: 5202 PKKEKPMEREAQHLEEKPLLKEKELPVSAEKAIEEKPLEKPFTPKDKKGEEVKPKKEKPT 5261

Query: 4414 TKKMQP 4419
             ++ +P
Sbjct: 5262 EREAKP 5267



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 5/109 (4%)

Query: 1031 KRTEEEVKI--TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
            KR+  E+ +   Q P F  PLK   ++ EG+    + ++    +    V+W  +G+ +  
Sbjct: 2019 KRSTAEIMMGDIQPPFFQKPLKD-KEVKEGKPFKLDVKITALPEAN--VKWLKDGEPLKP 2075

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             +  +T        L I     ED G Y   A N AG A   A + VE+
Sbjct: 2076 GDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVES 2124



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 4/85 (4%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR-TTHDFGF 2565
            +P F + LT  S +  G     E RV   G P  +  W+ +  E++  SRF   T     
Sbjct: 2395 QPKFAERLTNVS-ISSGDTIVLECRVT--GKPRPQVAWFKDDKEIRQDSRFSFETRPGDV 2451

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
              L I  V  +D G Y C A N AG
Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAG 2476



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            I EG+ A F+ R+   G P  +VEW R+ + I+   R     +     +TI   +  DEG
Sbjct: 3071 IMEGKMAKFEARVS--GLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEG 3128

Query: 2448 VYMCRASNLLGE 2459
             Y C A++  G+
Sbjct: 3129 EYTCVATSKAGK 3140



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 3/104 (2%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P FV     I+ V EG H  FE  ++       +++W+KN   +  G +F       +  
Sbjct: 2493 PFFVKELVDID-VTEGGHERFEVVVDGYPKP--EIDWYKNDILIRPGPKFDIKEHGDHHT 2549

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
            L + D   E++G  TC+A N  G    SC +     T   + TQ
Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEKTIPPKITQ 2593



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 3/86 (3%)

Query: 3972 PPRFVTQIQS-QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            PP F  +     T   E     FE  ++  G P   VEW  +  P+   + +        
Sbjct: 3251 PPHFTEEAPKIPTDFEEGGDITFEATVS--GRPRPDVEWHKDEAPISESSHYHLHRSNDT 3308

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGM 4056
             ++    V P+DSG Y C ATN  GM
Sbjct: 3309 YSLTIRGVGPDDSGAYTCTATNECGM 3334



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 18/61 (29%), Positives = 28/61 (45%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+ W  + K IT  N+     D G  +L +     ED G+YT +A    G ++    + V
Sbjct: 4424 TITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSERRFDLRV 4483

Query: 1136 E 1136
            E
Sbjct: 4484 E 4484



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L +I  + EG +  F+ ++T + +P  KV WY NGK ++         D     
Sbjct: 2300 PKFERNLKDI-TIAEGCSTRFDVQVTGSPEP--KVFWYHNGKLVQPRDHVDIVHDDEHSS 2356

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            L +     + SG+Y C A N  G+  + A + +
Sbjct: 2357 LILMHCPLDLSGKYTCVAENEVGQVQSAARLHI 2389



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 17/61 (27%), Positives = 30/61 (49%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            I W K+   +T   +   T D G+ +L++     +D G+YTC A    G +     +++E
Sbjct: 4425 ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSERRFDLRVE 4484

Query: 2736 D 2736
            D
Sbjct: 4485 D 4485



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 39/168 (23%), Positives = 66/168 (39%), Gaps = 22/168 (13%)

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP------------QGMSGEKIKEL 3811
            D G Y C  ++ +G +T T  +   +      +   P            + MS  KI + 
Sbjct: 4764 DTGSYKCTISSDYGRSTRTFNVEIDSDMPEPAQPDYPKVEPFHEKPLSEETMSVTKILQD 4823

Query: 3812 ERGRISDAPKE---EPIVSTP---PKFI--TQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            E+      P++   E ++S P   P FI   ++K   V E   ++   +V  K  PK  +
Sbjct: 4824 EKALEPARPEKNIIEDVLSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVTGK--PKPSV 4881

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            EW ++ + + S    +   +    SL I      D G Y  +  ND G
Sbjct: 4882 EWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVG 4929



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 5/86 (5%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI-TKTHDFG 2432
            Q P F +PL++ + ++EG+    D ++  +  P   V+W ++ + ++      T+ H   
Sbjct: 2031 QPPFFQKPLKDKE-VKEGKPFKLDVKITAL--PEANVKWLKDGEPLKPGDHFKTERHGDT 2087

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
            Y  + I     EDEG Y C A N  G
Sbjct: 2088 YF-LIIPEADVEDEGRYRCEAVNNAG 2112



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F   + D I + EGG   FE  ++  G     ++W K+   +    +     +  +  
Sbjct: 2493 PFFVKELVD-IDVTEGGHERFEVVVD--GYPKPEIDWYKNDILIRPGPKFDIKEHGDHHT 2549

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            L +K     + G  TC+A N+ GQA  S  + I  K
Sbjct: 2550 LIVKDCRPEETGKLTCKARNSAGQAICSCFVQINEK 2585



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 15/49 (30%), Positives = 24/49 (48%)

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            ++W  +G+V+E   R+ +  D     L ++   E D G Y C   NK G
Sbjct: 4107 VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAG 4155



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 45/204 (22%), Positives = 85/204 (41%), Gaps = 10/204 (4%)

Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279
            E    ++  T  EK  EE +    +        LK K + E E E   SV++   E+   
Sbjct: 5605 EEKPLEKPITRKEKKVEEVKPKTEKPTEREAKPLKEKPLVE-EKELTVSVEKAVEEK--- 5660

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339
                LE     KE ++ E   +   P ++   +   K + +  E  +   + V E+ ++K
Sbjct: 5661 ---PLEKPITRKEKKVEEVKPKKEKPTEREAKSLDKKPLVEEKELPVSAKKAVEEKPLEK 5717

Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI-TSTETTEIEHKAQTQE 4398
             +T++ +  +  +          AK  + +K +V +KE+T  +  + E   +E     +E
Sbjct: 5718 PITREEKKVEEVKPKTEKPTEREAKPLK-EKPLVEEKELTVSVEKAVEEKPLEKPITRKE 5776

Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRV 4422
            + VE  VKP K     ++ +P  V
Sbjct: 5777 KKVE-EVKPKKEKPTEREAKPREV 5799



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 12/170 (7%)

Query: 3900 GEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR-GMK-----RSEALTQMEATIKKY 3953
            G  +C A+ DF ++F     S KK   +I+ +++ R GM      RS+     E  +   
Sbjct: 1957 GIEMCVAIQDFEDEF--GDFSLKKKESVIVLDKISRPGMYKVVRLRSDGSRGDEMWVPPN 2014

Query: 3954 TSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG 4013
              +   +  ++   D  QPP F   ++ +  + E +  K + ++  + + N+K  W  +G
Sbjct: 2015 VLQKKRSTAEIMMGDI-QPPFFQKPLKDK-EVKEGKPFKLDVKITALPEANVK--WLKDG 2070

Query: 4014 KPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
            +PL   + F          +       ED G Y C A N  G   T+A I
Sbjct: 2071 EPLKPGDHFKTERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADI 2120



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            +P+F   L   + I  G +   E RV  +      V W+ + K+I   +R       G V
Sbjct: 2395 QPKFAERLTNVS-ISSGDTIVLECRVTGKP--RPQVAWFKDDKEIRQDSRFSFETRPGDV 2451

Query: 1102 A-LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
              L I  V  +D G Y  +A N AG+    A +TV  R +
Sbjct: 2452 CVLTIRGVTPDDEGSYKCIATNPAGQDDTVAELTVAKRGN 2491



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 16/47 (34%), Positives = 23/47 (48%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY 4157
            P F      V++  G+     CRVTG P+P+V W  +   I   SR+
Sbjct: 2396 PKFAERLTNVSISSGDTIVLECRVTGKPRPQVAWFKDDKEIRQDSRF 2442



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 2/71 (2%)

Query: 83   FAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEG 142
            F     A FE ++ G P P V W +    +   +++  R +     ++L   ++   DEG
Sbjct: 2848 FLADNKAIFEVEITGKPEPKVEWLKNDVLIESGDRFEPRSDGTVYTLTLRGSRL--DDEG 2905

Query: 143  EYTCTARNQYG 153
            E  CTA N  G
Sbjct: 2906 EIKCTATNSAG 2916



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 2/71 (2%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984
            EG  +  E  V  +  PD  +EW+ +   + + S + L       +L +  V   DSG Y
Sbjct: 3267 EGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAY 3324

Query: 2985 TCKAYNKRGEA 2995
            TC A N+ G A
Sbjct: 3325 TCTATNECGMA 3335



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)

Query: 87   GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146
            G+ K + ++ G P P VSW +   P+V  N++ + Y+ +     L+IK   P   G Y C
Sbjct: 3869 GDIKLQTRVTGFPEPDVSWFKDGIPVVP-NEHIV-YHIRDDVHILIIKSPTPLYAGTYKC 3926

Query: 147  TARNQYG 153
             A N+ G
Sbjct: 3927 VATNRRG 3933



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 2410 VEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            V+W ++ ++IEDS R     D     +TI    ++D G Y C  +N  G
Sbjct: 4107 VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAG 4155



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 82   RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDE 141
            +F   G+     K +G PT  ++W + +  + + NK+   + E  G  SL + +    D 
Sbjct: 4406 KFTSEGDVTMTVKTKGRPT--ITWMKDEKIITQDNKFL--FTEDDGIYSLTVVKPTEEDR 4461

Query: 142  GEYTCTARNQYGEA 155
            G YTC A    G +
Sbjct: 4462 GLYTCIAETTDGRS 4475



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/103 (20%), Positives = 43/103 (41%)

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
            +++P Q         ++   V E    +   ++T K KP+++WL++   +      +M  
Sbjct: 4841 LSKPKQEPIFIETDEVKPFEVTEEGDIKMTVKVTGKPKPSVEWLKDDRPVLSDSHIKMTE 4900

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            E +   L I    + D G +T + T   G    +  + V+  T
Sbjct: 4901 EDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTT 4943



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 2651 YDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRND 2710
            ++   EG +V L  ++  +  P  ++ W K+   +     ++      + TL+I     +
Sbjct: 4964 FESTEEG-NVRLSVKITGKPVP--EVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPN 5020

Query: 2711 DSGIYTCKATNLLGEAVSTASIKIE 2735
            DSG Y C  TN  G++  T S++IE
Sbjct: 5021 DSGSYKCTLTNDAGKSTRTFSVEIE 5045



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 3/86 (3%)

Query: 3430 ENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPED 3489
            E+  EG N     ++T    P  +V W  + K +      R         L I    P D
Sbjct: 4965 ESTEEG-NVRLSVKITGKPVP--EVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPND 5021

Query: 3490 SGEYLCRAYNNYGEAVTTASMKVQGK 3515
            SG Y C   N+ G++  T S++++G+
Sbjct: 5022 SGSYKCTLTNDAGKSTRTFSVEIEGE 5047



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 16/52 (30%), Positives = 26/52 (50%)

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            + W K+ + +T  ++F    D G  +L ++    ED G+YTC A    G  E
Sbjct: 4425 ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGRSE 4476



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/78 (25%), Positives = 34/78 (43%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     + W  + K +     IR  +   +  L I      DSG+Y C  TN  G++  
Sbjct: 4979 TGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTR 5038

Query: 3135 SVKLECVDKSKGQKPRFT 3152
            +  +E   ++K +K + T
Sbjct: 5039 TFSVEIEGETKPEKGKPT 5056



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 16/56 (28%), Positives = 24/56 (42%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P  +V W ++EK +     I   H     ++TI      D G Y C  +N  G+
Sbjct: 4980 GKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGK 5035



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 3/104 (2%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            +PP F    KD  ++ EG+    +  +    + +  ++W  +G+ ++     +T      
Sbjct: 2031 QPPFFQKPLKD-KEVKEGKPFKLDVKITALPEAN--VKWLKDGEPLKPGDHFKTERHGDT 2087

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKP 3149
              L I      D G Y C A N  G+A     +      +G +P
Sbjct: 2088 YFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEP 2131



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 2926 GQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV-TLDLVDVYERDSGIY 2984
            G  + LE +V  K  P  ++ W+ + K + Q SRF   +  G V  L +  V   D G Y
Sbjct: 2410 GDTIVLECRVTGKPRP--QVAWFKDDKEIRQDSRFSFETRPGDVCVLTIRGVTPDDEGSY 2467

Query: 2985 TCKAYNKRGEAFTSSTVYCTSKDN 3008
             C A N  G+  T + +    + N
Sbjct: 2468 KCIATNPAGQDDTVAELTVAKRGN 2491



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/95 (24%), Positives = 38/95 (40%), Gaps = 2/95 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP+ T    DL +    + +   +     +    V+WF + + +     V          
Sbjct: 2588 PPKITQRLHDLSIDAGKTVNLTVKFFGTPEPL--VKWFMDDEEITNEDGVDIETSHCTSS 2645

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            L + GV   D G+Y C   N  GE + + K+ VKG
Sbjct: 2646 LVLVGVDTPDTGVYRCLVFNPAGEDSTNSKITVKG 2680



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 3/88 (3%)

Query: 1440 VTIKPRFVTR-PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            + + P F    PK   +  EG  + FE  +      +  VEW K+  P++    +     
Sbjct: 3248 IPVPPHFTEEAPKIPTDFEEGGDITFEATVSGRPRPD--VEWHKDEAPISESSHYHLHRS 3305

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
                +L I  +  +DSG YTC A N  G
Sbjct: 3306 NDTYSLTIRGVGPDDSGAYTCTATNECG 3333



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            ++ E   V LE +V     P+  ++W K+   + +      +    + TL INS   DD 
Sbjct: 3657 EVTEEGDVRLEVRVGGHPKPS--VQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDI 3714

Query: 2713 GIYTCKATNLLGEAVSTASIKIE 2735
            G Y   A+N  G A  T  + +E
Sbjct: 3715 GQYKVIASNHRGMASRTFDVNVE 3737



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI-TSIFNFGY 827
            RP F++   D+   Q       +  +     P   V W KD +PIT +  I  S+++  Y
Sbjct: 4498 RPTFVKD-DDMVPFQLTEEGDVKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTY 4556

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLG 852
             +L I     +D G Y   A N +G
Sbjct: 4557 -TLIIKSPTDKDEGIYKCTASNSVG 4580



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/62 (32%), Positives = 28/62 (45%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V+W KD +P+  +S I          L IKS +  D G Y C A N  G    S  + + 
Sbjct: 4638 VKWSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVNRAGTNIRSFVVNVN 4697

Query: 1003 TK 1004
            T+
Sbjct: 4698 TE 4699



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 19/63 (30%), Positives = 27/63 (42%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            VEW  +  P+   S            L I GV   D+G YTC ATN  G A  +  + ++
Sbjct: 3285 VEWHKDEAPISESSHYHLHRSNDTYSLTIRGVGPDDSGAYTCTATNECGMAKRTYNIDIE 3344

Query: 3651 GRQ 3653
              +
Sbjct: 3345 ASE 3347



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 17/60 (28%), Positives = 26/60 (43%)

Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            V+W  +G+V++   RY    D     L IL    +D G Y C   N  G    S  + ++
Sbjct: 4107 VQWMKDGEVIEDSKRYVIRQDDDLHMLTILGATEDDLGTYKCVVTNKAGFDTRSFDIGLE 4166



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 46/207 (22%), Positives = 79/207 (38%), Gaps = 27/207 (13%)

Query: 1998 EATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNA 2057
            + T+T        + W  + + + Q ++F  T D G  +L ++    ED G Y C A   
Sbjct: 4412 DVTMTVKTKGRPTITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETT 4471

Query: 2058 VGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTS 2117
             G +     ++V+          D+     I  L    RP  ++++     P  LT    
Sbjct: 4472 DGRSERRFDLRVE----------DDDTSTTI--LMDLVRPTFVKDDD--MVPFQLT---- 4513

Query: 2118 LENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI-RAGHRYRTTHDFGYVALDILYTYA 2176
                +EGD    +  V     P  T+ W  + + I    H   + +D  Y  L I     
Sbjct: 4514 ----EEGD---VKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTY-TLIIKSPTD 4565

Query: 2177 EDSGTYMCKATNKLGEAVNTCTLKVAG 2203
            +D G Y C A+N +G +     + + G
Sbjct: 4566 KDEGIYKCTASNSVGTSSQMFDVDIKG 4592



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 5/74 (6%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLDITHTYEEDSG 2844
            +EGD +     V     PT  + W  ++KP+      + S +D +Y +L I    ++D G
Sbjct: 4514 EEGD-VKLMVRVAGKPKPT--VTWTKDSKPITETDHIQVSVYDDTY-TLIIKSPTDKDEG 4569

Query: 2845 IYTCKATNSKGSAT 2858
            IY C A+NS G+++
Sbjct: 4570 IYKCTASNSVGTSS 4583



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 18/66 (27%), Positives = 29/66 (43%)

Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
            R  P  +++W K+   LT  + +         TL I S  +DD G Y C A N  G  + 
Sbjct: 4631 RGKPKPEVKWSKDDKPLTPNSNIVMEEMDDTYTLVIKSPSSDDRGTYKCTAVNRAGTNIR 4690

Query: 2729 TASIKI 2734
            +  + +
Sbjct: 4691 SFVVNV 4696



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 1/71 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFD 4168
            PP F        V+EG+  +   ++T  P+  V WL +G  +  G  +K    G  Y   
Sbjct: 2032 PPFFQKPLKDKEVKEGKPFKLDVKITALPEANVKWLKDGEPLKPGDHFKTERHGDTYFLI 2091

Query: 4169 IPKTRQYDTGK 4179
            IP+    D G+
Sbjct: 2092 IPEADVEDEGR 2102



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 1/52 (1%)

Query: 4133 RVTGHPKPRVMWLLNGNTIVNGSRYK-LTYDGMYHFDIPKTRQYDTGKIEVI 4183
            RV G PKP V W  N   +V  S +  L  D ++   I K  + D G  +VI
Sbjct: 4206 RVRGKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVI 4257



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 15/61 (24%), Positives = 30/61 (49%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P+  ++W+ + + +       + +     +L LV V   D+G+Y C  +N  GE  T+S 
Sbjct: 2616 PEPLVKWFMDDEEITNEDGVDIETSHCTSSLVLVGVDTPDTGVYRCLVFNPAGEDSTNSK 2675

Query: 3001 V 3001
            +
Sbjct: 2676 I 2676



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/103 (23%), Positives = 38/103 (36%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            +S+ +   +RP FI    +    +         ++     P   V+W KD   I +S   
Sbjct: 3634 DSVLDDDDERPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIISSPHF 3693

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                +    +L I     +D G Y V A N  G A  T  + V
Sbjct: 3694 MVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNV 3736



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/89 (28%), Positives = 35/89 (39%), Gaps = 2/89 (2%)

Query: 1186 PPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSA 1245
            P  V+E  ++ LE R+   G P   V+W  +   +     F          L I      
Sbjct: 3655 PAEVTEEGDVRLEVRVG--GHPKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQD 3712

Query: 1246 DTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
            D G+Y V A NH G A  +  V V   +D
Sbjct: 3713 DIGQYKVIASNHRGMASRTFDVNVEGAND 3741



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 17/55 (30%), Positives = 28/55 (50%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            P  +I+W+ +G+ L      K+TSD    T+ +     +D+G Y C   N  G+A
Sbjct: 3994 PFPEIDWFKDGRHLSPDDHIKITSDDDLYTVLIRQPTIKDTGKYKCIIKNIAGKA 4048



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 16/55 (29%), Positives = 27/55 (49%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK  V+W +N  P+  S+  + + +    +L ++  +  D G Y   A NE G
Sbjct: 4209 GKPKPTVKWTKNDEPVVPSSHFSVLMEDDVFSLLIRKPSKTDKGVYKVIATNEGG 4263



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/84 (22%), Positives = 35/84 (41%), Gaps = 10/84 (11%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            +P   +    +  F  GG+ K   K+ G P P V+W+R    +   + + M  +++    
Sbjct: 4289 APRFLDDGISSYEFTSGGDVKLTVKVTGRPYPTVTWSRDDKDIKPDDTFHMFSDDEN--- 4345

Query: 130  SLLIKQIGPGDEGEYTCTARNQYG 153
                      ++G Y CT  N+ G
Sbjct: 4346 -------PAENQGSYKCTIANEAG 4362



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 660  IEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
            ++  G PT  I W+K+ + I   ++F      G  SL ++    +D G YTC A +  G 
Sbjct: 4417 VKTKGRPT--ITWMKDEKIITQDNKFLFTEDDGIYSLTVVKPTEEDRGLYTCIAETTDGR 4474

Query: 720  AETKAVLHV 728
            +E +  L V
Sbjct: 4475 SERRFDLRV 4483



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 3/120 (2%)

Query: 2233 EVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292
            E+    I PP F   L+    V EGK   F+  V+    P   +++  +G+ L+    F 
Sbjct: 2024 EIMMGDIQPPFFQKPLKDK-EVKEGKP--FKLDVKITALPEANVKWLKDGEPLKPGDHFK 2080

Query: 2293 ITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEK 2352
                     L I     ED G Y  +A+N  G  ++   + V +          P+ +E+
Sbjct: 2081 TERHGDTYFLIIPEADVEDEGRYRCEAVNNAGRASTEADILVESADEGSEPEDEPQQMEQ 2140



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L  +V+ + +P   + W+K+ V L    R+K   +  +  ++I     +DS ++T   TN
Sbjct: 3764 LVLEVKIKGEPLPDVRWYKDDVPLDETCRIKIDAEGDIQIVTIKDANKEDS-VFT-NITN 3821

Query: 2722 LLGEAVSTASIKIE 2735
              G A+   SI +E
Sbjct: 3822 DFGTAIRRFSIDVE 3835



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 8/92 (8%)

Query: 634  YPPPQFIVPL---KSVTAME---GGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTS 687
            Y P + + P      VTA +    G +    R+   G P   ++W KN + +  SS F+ 
Sbjct: 4175 YEPSELVAPYYLEDGVTAFQMTDAGDVKLTVRVR--GKPKPTVKWTKNDEPVVPSSHFSV 4232

Query: 688  IFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
            +      SL +   +  D G Y   A +  G+
Sbjct: 4233 LMEDDVFSLLIRKPSKTDKGVYKVIATNEGGI 4264



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 5/72 (6%)

Query: 4111 PVFVSLPDAVT---VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGMYH 4166
            P FV   D V     EEG+  +   RV G PKP V W  +   I      +++ YD  Y 
Sbjct: 4499 PTFVKDDDMVPFQLTEEGD-VKLMVRVAGKPKPTVTWTKDSKPITETDHIQVSVYDDTYT 4557

Query: 4167 FDIPKTRQYDTG 4178
              I      D G
Sbjct: 4558 LIIKSPTDKDEG 4569



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 1/87 (1%)

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            V+    P   +EW  + + +   S  K+T +    +L + +  + D G+YT K  N  G 
Sbjct: 4871 VKVTGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGS 4930

Query: 2995 AFTSSTVYC-TSKDNLIERTQHPKGTE 3020
               +  V    +  +L E T  PK  E
Sbjct: 4931 GTRTFDVKVEDTTTSLFEGTVRPKFIE 4957



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            + EG    FE  V+        ++WY N   I    +        +  L +   R E++G
Sbjct: 2504 VTEGGHERFEVVVDGYPK--PEIDWYKNDILIRPGPKFDIKEHGDHHTLIVKDCRPEETG 2561

Query: 1115 VYTVVARNAAGEAQLSASMTVETRS 1139
              T  ARN+AG+A  S  + +  ++
Sbjct: 2562 KLTCKARNSAGQAICSCFVQINEKT 2586


>SB_31699| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 6119

 Score =  199 bits (486), Expect = 4e-50
 Identities = 250/1028 (24%), Positives = 410/1028 (39%), Gaps = 141/1028 (13%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGM 3105
            P F    +D+ D+ EG  A +   +  +G  +  +EW    + +    R+         M
Sbjct: 3527 PHFDHPIQDL-DVIEGDRAKFHVEV--SGKPAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
              L I   K TDSG Y+C A NK G+     +L    K K   P F     + E  +  +
Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAV--KEKMVTPSFAEGDAD-EPCEVWE 3640

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
             A  +  V     P   +EW+   +  +    +K  ++    +L I   +  DSG Y C+
Sbjct: 3641 GAPIKLIVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQ 3700

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFI 3285
            A N  G      T+    K  V  + +                  ++ P  P A  P F+
Sbjct: 3701 ATNDAG------TVTKTFKVVVNEQKV----------------VMRRQPIPPGAVKPSFL 3738

Query: 3286 TQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR-TFHDFGIVILDI 3344
             ++QD+ ++VEG +A    R+  V +P+  ++W+ + + +  G R    F + G+ +L I
Sbjct: 3739 QRMQDL-EIVEGSAARLCVRVQGVPEPE--IDWYKDNRVIREGGRVEFEFEEDGLCMLVI 3795

Query: 3345 LYCYEENSGEYECVATNKLGRDSTKANLKCTSK--ENLILDSQLP-----RGMEGGLEKL 3397
                + + G Y+CV +N  G+    A L   +   ++ + D+ L         E  +E +
Sbjct: 3796 RDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELI 3855

Query: 3398 QTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWY 3457
               +D+    K     +E+G  P FT+ L N E ++EG    F +R+       +KVEWY
Sbjct: 3856 S--DDTSDEEKTEGAPKEEGAPPEFTLVLRNRE-VKEGGVTKFASRVI--SKAPIKVEWY 3910

Query: 3458 WNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
             + +                    IS  +P  + E+     + Y   ++   +   G   
Sbjct: 3911 KDDRL-------------------ISSDWPRHTFEH---DEDLYAMNISNVKVADGGPYT 3948

Query: 3518 IILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHF 3577
             ++ ++      GT++  A    Y   +  + PE E G  P F+    +  + E S+A  
Sbjct: 3949 FVVSNKY-----GTVESKA----YLNVLPEMEPEFE-GISPRFSVKLKNQEVIEGSTARL 3998

Query: 3578 ECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNR 3637
            ECR+  V      V W+ + +PL+   + +   D     L +  V + D G Y   A N 
Sbjct: 3999 ECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNI 4056

Query: 3638 HGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRF 3697
             G    +  + VK        P             + LE    K      + E P  P  
Sbjct: 4057 AGRDVCTADISVK-------HPDTDEESDIDAVDARPLESKPSKP-----KTEIPK-PEI 4103

Query: 3698 TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDI 3757
             + ++D   V EG  V F+CR      P   + WF +G+P A+  R    +  G  +L I
Sbjct: 4104 VLGLRDRF-VVEGMSVRFNCRT--TSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTI 4160

Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS 3817
                  DAG Y C  +N  G A T+A +T                     ++EL + R S
Sbjct: 4161 KDCKLADAGIYKCEVSNVGGKAGTSAHLT---------------------VEELPKSRPS 4199

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
                   +V++PP+F  ++K   V    G   +  V     P   IEWY++ + +  G R
Sbjct: 4200 -------VVASPPRFQEELKG--VITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGR 4250

Query: 3878 YRTVYD----MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQV 3933
             R   D       VSL I  V   D G Y C A N  G DF+ AT+  K+L D   ++ +
Sbjct: 4251 IRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVKELDD---EDSI 4307

Query: 3934 PRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKF 3993
              G       T  EA   +       T      + + +PP F+ +++ Q  + E ET +F
Sbjct: 4308 QEGAMSLPKSTSDEALRMEDIPVAQST-----PLKRGEPPEFIRKLRDQ-FIQEKETARF 4361

Query: 3994 ECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNL 4053
             C++  +G P+   EW    KP+    R+T + D     +       ED G Y C +TN 
Sbjct: 4362 VCRV--IGRPDPTYEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNS 4419

Query: 4054 YGMDETKA 4061
             G D T A
Sbjct: 4420 SGTDTTTA 4427



 Score =  181 bits (441), Expect = 1e-44
 Identities = 235/924 (25%), Positives = 362/924 (39%), Gaps = 130/924 (14%)

Query: 1308 MQAPQFSR--ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
            M  P F+   A    E  EG  + L  +++  G     VEWF   +  K     +   E 
Sbjct: 3622 MVTPSFAEGDADEPCEVWEGAPIKLIVQIK--GKPAPTVEWFKEKRQAKRLKNVKLFTEG 3679

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
            D   L +    PEDSG Y CQATN  G    +  + V  +K ++     P G  K     
Sbjct: 3680 DKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVNEQKVVMRRQPIPPGAVK----- 3734

Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485
                              P F+ R + +E ++EG       +++ V +   +++W+K+ +
Sbjct: 3735 ------------------PSFLQRMQDLE-IVEGSAARLCVRVQGVPEP--EIDWYKDNR 3773

Query: 1486 PVTIGHRFR-PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR------- 1537
             +  G R      + G   L I D    D G Y C   N  G  + S  L          
Sbjct: 3774 VIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSG 3833

Query: 1538 -STTDIVRSTQNEAGLEQIQVL-EDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRA 1595
             S  D+  + + EA    I+++ +D S   +T+   +     P  T  L+N E+KEG   
Sbjct: 3834 VSDADLDFAARKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVT 3893

Query: 1596 HFERRLIPVSDATLKVEWYHNNKPLKSG-SRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
             F  R+I  S A +KVEWY +++ + S   R T  ++    A++I +    D G YT   
Sbjct: 3894 KFASRVI--SKAPIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVV 3951

Query: 1655 INALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFT 1714
             N  G   +     V  +    +E + EG  PR                         F+
Sbjct: 3952 SNKYGTVESKAYLNVLPE----MEPEFEGISPR-------------------------FS 3982

Query: 1715 MPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKY 1774
            + +K+  V E   A  E R+  VG P   V W R+  P+  S +     D  + AL +K 
Sbjct: 3983 VKLKNQEVIEGSTARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKD 4040

Query: 1775 VNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRRE 1834
            V+ ED G Y   A N  G  V ++ + V+   + + ES  ++   +  + + S       
Sbjct: 4041 VSEEDDGHYKAVARNIAGRDVCTADISVKHPDTDE-ESDIDAVDARPLESKPSKPKTEIP 4099

Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
              E+ +    RF+          EG S  + CR    P P   V W+ +G+ L S  RY 
Sbjct: 4100 KPEIVLGLRDRFVV---------EGMSVRFNCRTTSQPKP--YVTWFKDGQPLASYGRYE 4148

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
             ++  G  +L I      D+G Y C+  N  G+A +S  L V+           E    +
Sbjct: 4149 VTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVE-----------ELPKSR 4197

Query: 1955 IQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWY 2014
               +    R++  ++    VV     G   K +    GHP       TPV      +EWY
Sbjct: 4198 PSVVASPPRFQEELKGVITVV-----GTTTKLSVPIIGHP-------TPV------IEWY 4239

Query: 2015 CNGRPVQQGHRFKTTYD----FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             + R V +G R +   D    F  V+L I      D G Y C A N  G   ++++VKV 
Sbjct: 4240 KDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVK 4299

Query: 2071 AKSGLYLDTLDEQRL---KKIQELEKYERPKPIEEEQP---GQRPVFLTALTSLENLKEG 2124
                   D++ E  +   K   +        P+ +  P   G+ P F+  L   + ++E 
Sbjct: 4300 ELDD--EDSIQEGAMSLPKSTSDEALRMEDIPVAQSTPLKRGEPPEFIRKLRD-QFIQEK 4356

Query: 2125 DRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMC 2184
            + A F CRV  I  P  T +W    + I  G RY    D     L+I     ED G Y C
Sbjct: 4357 ETARFVCRV--IGRPDPTYEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKC 4414

Query: 2185 KATNKLGEAVNTCTLKVAGHRNII 2208
             +TN  G    T  L V   R  I
Sbjct: 4415 VSTNSSGTDTTTARLTVEASRRPI 4438



 Score =  178 bits (434), Expect = 8e-44
 Identities = 181/713 (25%), Positives = 279/713 (39%), Gaps = 45/713 (6%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFD-- 4168
            P F S    V  EEG+  RF   V G PKP V+W      I    R+++      H    
Sbjct: 104  PSFTSKMKPVDAEEGQEVRFDVHVKGSPKPDVVWYKGSTMIGTHERFQIVEAAEDHVTLV 163

Query: 4169 IPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTE 4228
            I + +  D    +V+             L+V  R   +     +  R   D TT  + T 
Sbjct: 164  ISEVKLEDAETYKVVATNDVGKVTSRADLRVKERQ--FAPEFIDEERGPIDATTGDEVTL 221

Query: 4229 TELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQ 4288
            T       +  +   +        LK  +    E  W   +  K  +    K  E EN+ 
Sbjct: 222  TCSVSGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKC-EAENK- 279

Query: 4289 VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTE-EVTEQRVQKKVTQKPRI 4347
            + K SR  +   +   P     S T+  +  +  E    +   +VT +        K  +
Sbjct: 280  LGKASRAFDV--KVKAPKGDAPSFTIDLTHVRAIEGEESKLVCKVTGKPAPTIEWLKGEL 337

Query: 4348 PDPSESTVHG---KEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGP 4404
            P  +   V     K V     K T+    G  ++  +  S     I  + Q QER     
Sbjct: 338  PVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIA-ELQVQER----- 391

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
               S  P     ++       E+ +F+V   G+P P ++W +    I++   F I   S 
Sbjct: 392  ---STKPEIEDSLRDVSALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERFTIAEESD 448

Query: 4465 KSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523
            +   LII+ +   D+  +  VA N  G A+  A L V E+       ++ P F    ++ 
Sbjct: 449  EVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEE-------LIGPRFEKMKESF 501

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
             V  G+ V L  +VTG    ++ W K+GK V+        E D    L I E+   DSG 
Sbjct: 502  TVVEGESVELVARVTGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGL 561

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y C A N +G A    +    L     KPK         PEI+  L+     EG     S
Sbjct: 562  YRCTARNKSGTA----DMTFQLDVQPKKPK------GTAPEIVSELRPVEATEGDDAVLS 611

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C I GKP+PT++W K    +K S+  +      E  L I     +D+GDY C+  N  G 
Sbjct: 612  CTISGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGS 671

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
                 KLKV    + +    L P++ +   EG+  Q   ++    KP I+W R   +I E
Sbjct: 672  AESKTKLKVIAFARPEFRTKLKPVKAV---EGEEVQLDVKVEGYPKPDIEWYRGTTMIVE 728

Query: 4764 TPDFQMIHEGNN---AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +  F+++ E        L+I     +DTGT    AT A+G+  + A L VK +
Sbjct: 729  SGRFKVMEEEEEDGLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKER 781



 Score =  177 bits (431), Expect = 2e-43
 Identities = 120/408 (29%), Positives = 185/408 (45%), Gaps = 25/408 (6%)

Query: 4410 PPIFTKKMQ-PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            P I T  ++ P  + E +  R  V   G P+P ++WY++   I+ S    + +  ++  L
Sbjct: 3333 PEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSL 3392

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I  V  ED+ V   VA N  G+A  S  +V+E K+         P F     +  V  G
Sbjct: 3393 AIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKKPA-------PLFIAPLHDQEVVEG 3445

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY-TLLILEAYPQDSGKYECV 4587
            + +RL+ +V  T    V W K+G+  + D  +   E DG + TL+I  A  +D G YEC+
Sbjct: 3446 ETIRLECRVRATPRPMVEWKKDGRTFKEDY-HIYTEFDGQHCTLVIKGAQIEDEGAYECI 3504

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N  G  R  A+  V             K A   P    P++D  V EG   +F  ++ 
Sbjct: 3505 AKNKEGRGRSVAQLTV-------------KEALIIPHFDHPIQDLDVIEGDRAKFHVEVS 3551

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMS--RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            GKP   V+W KGD+ ++      +   R    Y L I+   P D G Y C+A N AG  T
Sbjct: 3552 GKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSGKYTCIARNKAGENT 3611

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
               +L V +     +           V+EG P +   QI  K  PT++W +E        
Sbjct: 3612 CHGRLAVKEKMVTPSFAEGDADEPCEVWEGAPIKLIVQIKGKPAPTVEWFKEKRQAKRLK 3671

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            + ++  EG+  +L+I     ED+G + C+AT  AG V  + K+VV  +
Sbjct: 3672 NVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVNEQ 3719



 Score =  177 bits (430), Expect = 2e-43
 Identities = 111/418 (26%), Positives = 201/418 (48%), Gaps = 18/418 (4%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            V+GP    + PI   K++P    E E+ + +  F G+P P  +W R+   I++S   QI 
Sbjct: 877  VKGP--KGEAPIILSKLRPVETEEGEETKLKCTFTGKPAPTCEWTRDGIRIRSSRMVQID 934

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
            T    S LII++  ++D  ++    +N  GT   SA ++V E  + G G ++        
Sbjct: 935  TTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNEVEK-GVGPVIEEKL---- 989

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYP 4578
            ++V V  G+      +V+G   +D  W K+   +  + R  I+E  ++G ++L I +  P
Sbjct: 990  KDVTVMPGEEAEFSIRVSGRAEVD--WFKDEVMLNDEGRF-IMEGGDNGRFSLTISDVRP 1046

Query: 4579 QDSGKYECVAINSAGEARCDAECVV--SLPATKDKPKPQT-KAANAPPEIIEPLKDKIVA 4635
            +D G Y+C+  N +G+    A+  +  ++ A ++    +T     + P+I +PL+   V 
Sbjct: 1047 EDKGTYKCLVFNESGKVTTRAKLCIKEAIVAPEEVDAAETVPIEGSAPKITKPLESVEVN 1106

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            EG+  +  C + G P PTV+W K    ++ S   +     +   L   +A PED G+YKC
Sbjct: 1107 EGEDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKC 1166

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
               N  G+ +   ++KV    + +    ++P   + V EG  A F+ ++    K  ++W 
Sbjct: 1167 TVINEHGKASTTGEVKVNVLSRPEFKIKMSP---VEVTEGSEAAFEVRVEGFPKLQVEWF 1223

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +    I ++  +    + N   ++I N   ED G + C AT  AG+  + A L VK +
Sbjct: 1224 KGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKER 1281



 Score =  173 bits (420), Expect = 4e-42
 Identities = 176/735 (23%), Positives = 295/735 (40%), Gaps = 66/735 (8%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            V P++ ++  +A   P  V    A  V EG   +  CRVTG P P + W  +   +    
Sbjct: 2834 VKPKRGLKPGEAA--PEIVQRLKACEVPEGSSFKLRCRVTGTPTPTIEWYKSNMPLKPNG 2891

Query: 4156 RYKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHD--DYRGVLKN 4212
            R  + + G  Y  +  +T   D G+  ++             L + P      +R  L  
Sbjct: 2892 RVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVSPPSFRHRLTA 2951

Query: 4213 APRPWYDET---TQYQRTETELEKTFEERQVLQRQG---VIDHRPELKPKVI----KEPE 4262
                  DET    + ++  T +E  ++E+Q +   G   VI+   E    ++    K  +
Sbjct: 2952 VEVDEGDETRFDVRLKKEPTSVE-WYKEQQRIFTDGHFEVIEGEEECLYSLVISNTKVAD 3010

Query: 4263 TEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIP-GDKVTSNTVAKSMAQR 4321
                +     ++ +   + + L NE++I           Y +  GD +T + V K     
Sbjct: 3011 AGGYKCTALNESGKSSTRAELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVKG--NP 3068

Query: 4322 YEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRK 4381
            Y +     +E       KK+    R    S +  H         K   K  VG       
Sbjct: 3069 YPEIRWYKDEFLAME-SKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVG------- 3120

Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
             T+T++  ++ +A+  + ++         P F ++++     +   ARFE +  G P P 
Sbjct: 3121 -TATKSFTVDVEAKKSKGII---------PEFFRQLRRVEAVQGSTARFECKVSGHPEPQ 3170

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLV 4499
            I W ++   +   P + I  F    +  L   +   ED   +  VA N  G A   A+LV
Sbjct: 3171 IAWLKDGKELA-IPRY-IKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASLV 3228

Query: 4500 VEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIR 4559
            + +        +V P F    +N+ V  G   +   +V G     V W K GKK++   R
Sbjct: 3229 LSKP-------LVMPEFKERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKKIKSHAR 3281

Query: 4560 -NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKA 4618
             +    E  TYTL I +   +D G Y+CVA N AG+ +C     V             K 
Sbjct: 3282 FSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV-------------KE 3328

Query: 4619 ANAPPEIIEPLKD--KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD 4676
               PPEI   + +   ++ EG  +     + G P+P +QWYK   LI+ S +  +S    
Sbjct: 3329 RMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGS 3388

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
             Y+L I    PED G  KCVA N AG  + +  + +     A     + PL D  V EG+
Sbjct: 3389 RYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKKPAPLF--IAPLHDQEVVEGE 3446

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
              + + ++ +  +P ++W ++G    E        +G +  L+I     ED G + C A 
Sbjct: 3447 TIRLECRVRATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCTLVIKGAQIEDEGAYECIAK 3506

Query: 4797 TAAGQVETSAKLVVK 4811
               G+  + A+L VK
Sbjct: 3507 NKEGRGRSVAQLTVK 3521



 Score =  168 bits (409), Expect = 8e-41
 Identities = 121/464 (26%), Positives = 214/464 (46%), Gaps = 32/464 (6%)

Query: 4360 VHVAKQKQTQKEVV-GDKEITRKITSTE-----TTEIEHKAQTQERVVEGPVKPSKPPIF 4413
            + V   ++T+ ++V G+ ++T K T  +     T  + ++  + E   +  V     P F
Sbjct: 629  IRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIAFARPEF 688

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS---ILII 4470
              K++P +  E E+ + +V+ +G P P I+WYR    I  S  F++     +     L+I
Sbjct: 689  RTKLKPVKAVEGEEVQLDVKVEGYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGLYSLVI 748

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTSGQ 4529
             ++ ++D+     VA N  G A   A+L V+E+          P F    +  + VT G 
Sbjct: 749  SKLQLDDTGTIKVVATNASGKATSRADLEVKERE-------FAPEFEGDEEGPIVVTEGN 801

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V +  +V      DV W K+G+ +    +  I      +TL I  +  +D+G Y+C A 
Sbjct: 802  EVSIQLRVKANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEAS 861

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N  G+A    +  V +   K +           P I+  L+     EG+  +  C   GK
Sbjct: 862  NRLGKASRSFDVKVQVKGPKGEA----------PIILSKLRPVETEEGEETKLKCTFTGK 911

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P PT +W +    I+ S+  Q+  T D  TL I E   +DEG YKC   N  G V+ +A+
Sbjct: 912  PAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAE 971

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            + V + ++         L+D+ V  G+ A+F  +++ + +  + W ++  ++ +   F +
Sbjct: 972  VLVNEVEKGVGPVIEEKLKDVTVMPGEEAEFSIRVSGRAE--VDWFKDEVMLNDEGRF-I 1028

Query: 4770 IHEGNNA--VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +  G+N    L I +   ED GT+ C     +G+V T AKL +K
Sbjct: 1029 MEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIK 1072



 Score =  168 bits (408), Expect = 1e-40
 Identities = 166/691 (24%), Positives = 281/691 (40%), Gaps = 61/691 (8%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+   ++    +G  AKF  ++ G P   V W +    L    + S+  + +T    L
Sbjct: 3527 PHFDHPIQDLDVIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFL 3586

Query: 132  LIKQIGPGDEGEYTCTARNQYGE-------AICSVYIQP---EGXXXXXXXXXXXXXYRH 181
             I    P D G+YTC ARN+ GE       A+    + P   EG              + 
Sbjct: 3587 TITNCKPTDSGKYTCIARNKAGENTCHGRLAVKEKMVTPSFAEGDADEPCEVWEGAPIKL 3646

Query: 182  VSETVEHKAYGTQGYTTE-QSRQTQKVA-YTNGTDHSST--DDFKVDTFEYRLLREVSFR 237
            + +     A   + +  + Q+++ + V  +T G  H          D+  YR  +  +  
Sbjct: 3647 IVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRC-QATNDA 3705

Query: 238  ESITKRYVGESDVQISTEIDRSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPR 296
             ++TK +    + Q      + + P +  P   Q+ ++ ++ EG+ A+  V++ G P P 
Sbjct: 3706 GTVTKTFKVVVNEQKVVMRRQPIPPGAVKPSFLQRMQDLEIVEGSAARLCVRVQGVPEPE 3765

Query: 297  VTWFKNGQRLINSNKHEI-ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            + W+K+ + +    + E          L +R+  KSD G Y  +  N  G    S  L +
Sbjct: 3766 IDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFI 3825

Query: 356  ESPT-ESYVQDQRSQYITDTQQRET-----------EERIEIS--EKALAPQFVKVCQDR 401
            E+   +S V D    +    + RE+           EE+ E +  E+   P+F  V ++R
Sbjct: 3826 ETHGFDSGVSDADLDFAARKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNR 3885

Query: 402  DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
            +V EG +T+F  RV  +   +V W+ +DR I  D+      ++   +A+ I+NV ++D G
Sbjct: 3886 EVKEGGVTKFASRVISKAPIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGG 3945

Query: 462  VVTCVARNKSGETAFQCRLNVI-EKE---QVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
              T V  NK G    +  LNV+ E E   + ++P+F  +     V EG    L  R VG+
Sbjct: 3946 PYTFVVSNKYGTVESKAYLNVLPEMEPEFEGISPRFSVKLKNQEVIEGSTARLECRIVGS 4005

Query: 518  PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRAR 577
            P P + W +D  P+I + + ++  DG    L +      D   Y+  A+N+AG     A 
Sbjct: 4006 PVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTAD 4065

Query: 578  LYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYIPPGEEDRVYPPP 637
            +            K       + +                 E  +P I  G  DR     
Sbjct: 4066 I----------SVKHPDTDEESDIDAVDARPLESKPSKPKTEIPKPEIVLGLRDR----- 4110

Query: 638  QFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLD 697
             F+V        EG  + F  R      P   + W K+GQ + +  R+      G  SL 
Sbjct: 4111 -FVV--------EGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLT 4159

Query: 698  MLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +    + D+G Y C   +  G A T A L V
Sbjct: 4160 IKDCKLADAGIYKCEVSNVGGKAGTSAHLTV 4190



 Score =  167 bits (407), Expect = 1e-40
 Identities = 122/424 (28%), Positives = 199/424 (46%), Gaps = 36/424 (8%)

Query: 4405 VKPSKP-PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT-F 4462
            ++  KP P+F   +    V E E  R E      P P+++W ++    K   D+ I+T F
Sbjct: 3424 IESKKPAPLFIAPLHDQEVVEGETIRLECRVRATPRPMVEWKKDGRTFKE--DYHIYTEF 3481

Query: 4463 STKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
              +   L+I+   +ED   +  +A+N+ G  +  A L V+E        ++ P F    Q
Sbjct: 3482 DGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKE-------ALIIPHFDHPIQ 3534

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT--YTLLILEAYPQ 4579
            +++V  G   +   +V+G     V WLK  ++++   R  + E+  T  Y L I    P 
Sbjct: 3535 DLDVIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPT 3594

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            DSGKY C+A N AGE  C     V       K K  T +  A  +  EP +   V EG  
Sbjct: 3595 DSGKYTCIARNKAGENTCHGRLAV-------KEKMVTPSF-AEGDADEPCE---VWEGAP 3643

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            I+   +I GKP PTV+W+K  +  K  K  ++    D++ L I +A PED G+Y+C A N
Sbjct: 3644 IKLIVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATN 3703

Query: 4700 SAGRVTVAAKLKVTQ----------PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749
             AG VT   K+ V +          P  A     L  ++D+ + EG  A+   ++    +
Sbjct: 3704 DAGTVTKTFKVVVNEQKVVMRRQPIPPGAVKPSFLQRMQDLEIVEGSAARLCVRVQGVPE 3763

Query: 4750 PTIQWLREGALIPETPDFQM-IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P I W ++  +I E    +    E    +L+I +  + D G + C  + AAG+ + SA+L
Sbjct: 3764 PEIDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAEL 3823

Query: 4809 VVKS 4812
             +++
Sbjct: 3824 FIET 3827



 Score =  167 bits (406), Expect = 2e-40
 Identities = 169/725 (23%), Positives = 300/725 (41%), Gaps = 57/725 (7%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            V+  K   P   + L     +E GE ++  C+VTG P P + WL     +    R +  +
Sbjct: 291  VKAPKGDAPSFTIDLTHVRAIE-GEESKLVCKVTGKPAPTIEWLKGELPVTTSLRVRTDF 349

Query: 4162 D-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDE 4220
            +  +    I  TR  D G  +V+             L+V  R          + +P  ++
Sbjct: 350  EKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQER----------STKPEIED 399

Query: 4221 TTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNK 4280
            + +           F+ R   + +  ++ R      VI++ E   + ++  + +E +   
Sbjct: 400  SLRDVSALPGERVKFKVRIGGKPKPKVEWRK--GKSVIEDGE---RFTIAEESDEVFSLI 454

Query: 4281 LQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSM-AQRYEDNLDQTEEVTEQRVQ- 4338
            +Q+LE        R +      A   + +   TV + +   R+E   +    V  + V+ 
Sbjct: 455  IQDLEETDA---GRYKCVATNEAGEAESMAQLTVNEELIGPRFEKMKESFTVVEGESVEL 511

Query: 4339 -KKVTQKPRIPDPSESTVHGKEV----HVAKQKQTQKEVVGDKEITRKITSTETTEIEHK 4393
              +VT KP  P+  E T  GK V    +V  +++  + V+  +E +R  +        +K
Sbjct: 512  VARVTGKP-APE-IEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNK 569

Query: 4394 AQTQERVVEGPVKPSKP----PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449
            + T +   +  V+P KP    P    +++P    E + A       G+P+P I+W +   
Sbjct: 570  SGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAVLSCTISGKPVPTIEWLKNGI 629

Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
             +K+S   +      +  L I+    +D   +  +  N  G+A+    L V    R    
Sbjct: 630  RVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIAFAR---- 685

Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL---EED 4566
                P F    + V    G+ V+LD KV G    D+ W +    +    R K++   EED
Sbjct: 686  ----PEFRTKLKPVKAVEGEEVQLDVKVEGYPKPDIEWYRGTTMIVESGRFKVMEEEEED 741

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
            G Y+L+I +    D+G  + VA N++G+A   A+    L   + +  P+ +     P   
Sbjct: 742  GLYSLVISKLQLDDTGTIKVVATNASGKATSRAD----LEVKEREFAPEFEGDEEGP--- 794

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
                  +V EG  +    ++   P   V W+K  + I  S    + R  +E+TL I  + 
Sbjct: 795  -----IVVTEGNEVSIQLRVKANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSS 849

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP-ALTPLRDIVVYEGQPAQFKTQIT 4745
             ED G YKC A N  G+ + +  +KV         P  L+ LR +   EG+  + K   T
Sbjct: 850  LEDTGVYKCEASNRLGKASRSFDVKVQVKGPKGEAPIILSKLRPVETEEGEETKLKCTFT 909

Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             K  PT +W R+G  I  +   Q+    +++ L+I  T  +D G + C      G V TS
Sbjct: 910  GKPAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTS 969

Query: 4806 AKLVV 4810
            A+++V
Sbjct: 970  AEVLV 974



 Score =  167 bits (406), Expect = 2e-40
 Identities = 127/474 (26%), Positives = 213/474 (44%), Gaps = 32/474 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P+ + K +N ++ EG+ A+ + ++ G+P P V W+++ + LI S K+++    +H  L V
Sbjct: 3979 PRFSVKLKNQEVIEGSTARLECRIVGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIV 4038

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
            ++  + D GHY  +A N  G  V +  ++V+ P      D  +      + + ++ + EI
Sbjct: 4039 KDVSEEDDGHYKAVARNIAGRDVCTADISVKHPDTDEESDIDAVDARPLESKPSKPKTEI 4098

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
             +    P+ V   +DR V EG   RF+CR T +P P VTWF  D Q    Y    + + +
Sbjct: 4099 PK----PEIVLGLRDRFVVEGMSVRFNCRTTSQPKPYVTWF-KDGQPLASYGRYEVTSVA 4153

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE----KEQVVA--PKFVERFST 499
            G  +L I +  L+D+G+  C   N  G+      L V E    +  VVA  P+F E    
Sbjct: 4154 GAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPSVVASPPRFQEELKG 4213

Query: 500  LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGAST---LDIPRAKA 555
            +    G    L+   +G PTP I W KD   ++    +R   D  G  T   L I   + 
Sbjct: 4214 VITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRL 4273

Query: 556  SDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQK-RLHLPRPTKVXXXXXXXXXXXXY 614
            +D   Y+C A+N +G+  + A +           Q+  + LP+ T               
Sbjct: 4274 TDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDI----- 4328

Query: 615  LRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLK 674
               V ++ P +  GE      PP+FI  L+     E     F  R+  +G P    EWL+
Sbjct: 4329 --PVAQSTP-LKRGE------PPEFIRKLRDQFIQEKETARFVCRV--IGRPDPTYEWLR 4377

Query: 675  NGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
              + I    R+T +      +L++    ++D G Y C + +++G   T A L V
Sbjct: 4378 GDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTV 4431



 Score =  163 bits (397), Expect = 2e-39
 Identities = 118/409 (28%), Positives = 180/409 (44%), Gaps = 26/409 (6%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI--HTFSTKSIL 4468
            PIF +K++     E E  RFEV+    P P ++W++ +  I +   F I     S   +L
Sbjct: 1470 PIFQQKLKAVSTIEGESTRFEVKLSAMPRPTVEWFKSSSQIYDGGRFTITEEENSGVYVL 1529

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTS 4527
            +I    +ED+  +  VA N  G     A L V E        +  P F   A+  +  T 
Sbjct: 1530 VIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEV-------LTVPEFMDKAEGPIEKTE 1582

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G  + L  +V G    ++ W K  + +    R      D  +T+ + +    DSG Y+CV
Sbjct: 1583 GDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCV 1642

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N AG          S   T +    + K     P+II  L  K V EG  +   C + 
Sbjct: 1643 ARNKAG----------SSSRTFNLDVQKKKVIGNAPDIITHLISKEVKEGGTVTLECTVS 1692

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            GKP P ++WYK       ++    +      ++  ++A   D+G+YKCVA N  G    +
Sbjct: 1693 GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSS 1752

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            A+L VT P + +    L PL    V EG  A+F  +I S  KP ++W R    I ++   
Sbjct: 1753 ARLTVTVPSKPEFKQKLRPLE---VVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRH 1809

Query: 4768 QMI--HEGNNAV-LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            Q+   +EG++   L+I NT  ED   + C A   AG+    A L V  K
Sbjct: 1810 QITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK 1858



 Score =  161 bits (392), Expect = 1e-38
 Identities = 108/382 (28%), Positives = 168/382 (43%), Gaps = 20/382 (5%)

Query: 4432 VEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
            +E  G P P I+WY     I  +   Q+   S+K+ + +  V ++DS ++   A N  GT
Sbjct: 2179 LEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGT 2238

Query: 4492 AKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                 N+ V+ KR +G      P+     ++V V  G+   L+  V+GT    + W ++G
Sbjct: 2239 GSKQFNINVQPKRPEG----TEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDG 2294

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
             +V+   R +   E+G   L+I E + +D G Y+C   N  G     A   + + AT+  
Sbjct: 2295 LRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI-IVATR-- 2351

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671
                       PE  E L    V EG   +F  ++ G P P V+WY G   I     F++
Sbjct: 2352 -----------PEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEI 2400

Query: 4672 SRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD 4729
                +   Y+L + E   ED G YKC+A N AG+ T  A L+V +   A           
Sbjct: 2401 ESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQFAPEFETGEERGP 2460

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            IVV EG     K  + +  KP + W ++G    E     +   GN   L I N   ED+G
Sbjct: 2461 IVVPEGGETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSG 2520

Query: 4790 TFTCRATTAAGQVETSAKLVVK 4811
            ++ C A    G  + S  + V+
Sbjct: 2521 SYKCEARNKLGFADKSFTIRVE 2542



 Score =  161 bits (392), Expect = 1e-38
 Identities = 115/414 (27%), Positives = 179/414 (43%), Gaps = 25/414 (6%)

Query: 4405 VKPS-KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
            ++PS  PP F  ++    V E ++ RF+V    EP   ++WY+E   I     F++    
Sbjct: 2936 IEPSVSPPSFRHRLTAVEVDEGDETRFDVRLKKEPTS-VEWYKEQQRIFTDGHFEVIEGE 2994

Query: 4464 TKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
             + +  L+I    V D+  +   A N  G +   A L+V E+       ++PP F     
Sbjct: 2995 EECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER-------LIPPGFEGPDH 3047

Query: 4522 -NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580
             +  +  G  + LD  V G    ++ W K+        +  +   D   +L +    P+D
Sbjct: 3048 GSYELQEGDTITLDAVVKGNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKD 3107

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
            SG Y+CV  N  G A       V + A K K           PE    L+     +G   
Sbjct: 3108 SGVYKCVLKNKVGTAT--KSFTVDVEAKKSK--------GIIPEFFRQLRRVEAVQGSTA 3157

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
             F CK+ G P P + W K  K +   +Y +     +   L   E  PEDEGDY CVA N 
Sbjct: 3158 RFECKVSGHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDEGDYTCVASNE 3217

Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
            AG  +  A L +++P           L++I V EG  AQF  ++  + +P ++W + G  
Sbjct: 3218 AGEASSHASLVLSKPLVMPEFK--ERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKK 3275

Query: 4761 IPETPDF-QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            I     F     E +   L I +   ED GT+ C A+  AG+V+ S +L VK +
Sbjct: 3276 IKSHARFSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329



 Score =  161 bits (390), Expect = 2e-38
 Identities = 211/876 (24%), Positives = 338/876 (38%), Gaps = 129/876 (14%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   VEW +     +    +    +     L +    PEDSG Y C+A N+ G    +
Sbjct: 3652 GKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKT 3711

Query: 1798 STLFV-QSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856
              + V + K  ++ +     A++        S  QR +D+E+                  
Sbjct: 3712 FKVVVNEQKVVMRRQPIPPGAVKP-------SFLQRMQDLEIV----------------- 3747

Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS-NDFGFAALDILTVYGEDSG 1915
             EG +A    R++  P+P   ++WY + +V++ G R      + G   L I      D G
Sbjct: 3748 -EGSAARLCVRVQGVPEPE--IDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRG 3804

Query: 1916 EYTCKAINNLGQAVSSIRLNVQSK--ESIIRDSQHESALEK------IQYLEDDSRYKRA 1967
             Y C   N  G+A  S  L +++   +S + D+  + A  K      I+ + DD+  +  
Sbjct: 3805 RYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELISDDTSDEEK 3864

Query: 1968 VQD-DSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG-HR 2025
             +         P+F   ++N EV EG      + +  ++   ++VEWY + R +     R
Sbjct: 3865 TEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRV--ISKAPIKVEWYKDDRLISSDWPR 3922

Query: 2026 FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL 2085
                +D    A++I      D G Y    +N  G         V++K+  YL+ L E   
Sbjct: 3923 HTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYG--------TVESKA--YLNVLPE--- 3969

Query: 2086 KKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDW 2145
                          +E E  G  P F   L + E + EG  A  ECR+  +  P   + W
Sbjct: 3970 --------------MEPEFEGISPRFSVKLKNQEVI-EGSTARLECRI--VGSPVPEVRW 4012

Query: 2146 FHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR 2205
            + + + +    +Y+   D  + AL +     ED G Y   A N  G  V T  + V  H 
Sbjct: 4013 YRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVK-HP 4071

Query: 2206 NIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQ 2265
                DT   + ++ +     +   ++ + E PK   P  V  LR    V EG +  F C+
Sbjct: 4072 ----DTDEESDIDAVDARPLESKPSKPKTEIPK---PEIVLGLR-DRFVVEGMSVRFNCR 4123

Query: 2266 VEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGH 2325
                  P   + ++ +G+ L S  R+ +T   G  SL I+ C   DAG Y  +  N  G 
Sbjct: 4124 T--TSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGK 4181

Query: 2326 CTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNI 2385
              ++  +TV             E L K R    A P              P F + L+ +
Sbjct: 4182 AGTSAHLTV-------------EELPKSRPSVVASP--------------PRFQEELKGV 4214

Query: 2386 DNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD----FGYVSMTISHV 2441
              +  G T      +I  G PT  +EW+++++ + +  RI    D    F  VS+TI  V
Sbjct: 4215 ITV-VGTTTKLSVPII--GHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDV 4271

Query: 2442 RDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEE- 2500
            R  DEG Y C A N  G               +  E    EG   + K       R E+ 
Sbjct: 4272 RLTDEGRYKCVAKNKSG---TDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDI 4328

Query: 2501 ------PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
                  P +  E P F + L     + E + A +  RV  +G P   +EW      +  G
Sbjct: 4329 PVAQSTPLKRGEPPEFIRKLR-DQFIQEKETARFVCRV--IGRPDPTYEWLRGDKPITDG 4385

Query: 2555 SRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             R+    D    TL+I      D GLY C + N +G
Sbjct: 4386 GRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSG 4421



 Score =  160 bits (389), Expect = 2e-38
 Identities = 118/409 (28%), Positives = 188/409 (45%), Gaps = 25/409 (6%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-LI 4469
            P   +K+Q       E+A F++   G P+P+++WYR +  I     + +         L 
Sbjct: 2647 PRILEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLT 2706

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVTSG 4528
            I  +  ED   + AV  N  G    +A L + E       G++ PSF  +  + +    G
Sbjct: 2707 IEYIDYEDEGAYKAVVINDSGEVSSTAVLRLAE-------GMIEPSFIGIEFEPITAYEG 2759

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L   V G     V +LK+   V    R ++      +TL + +   +DS  Y+ VA
Sbjct: 2760 SDIDLTFYVKGRPLPTVEFLKDEVPVFKSDRTELTSNGNRHTLYLSDLAVRDSATYKAVA 2819

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N AG AR   E +V       KPK   K   A PEI++ LK   V EG + +  C++ G
Sbjct: 2820 KNKAGVARRSVELLV-------KPKRGLKPGEAAPEIVQRLKACEVPEGSSFKLRCRVTG 2872

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P PT++WYK +  +KP+    +  T D+Y L   E    DEG Y  VA N  G V+ +A
Sbjct: 2873 TPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSA 2932

Query: 4709 KLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPT-IQWLREGALIPETPD 4766
            +L + +P  +   P+    L  + V EG   +F  ++  K +PT ++W +E   I     
Sbjct: 2933 EL-IIEPSVSP--PSFRHRLTAVEVDEGDETRFDVRL--KKEPTSVEWYKEQQRIFTDGH 2987

Query: 4767 FQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            F++I      +  L+I NT   D G + C A   +G+  T A+L+V  +
Sbjct: 2988 FEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036



 Score =  159 bits (387), Expect = 4e-38
 Identities = 192/779 (24%), Positives = 317/779 (40%), Gaps = 96/779 (12%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSC 1642
            ++++EI EG  A    R+  V +   +++WY +N+ ++ G R   E    G   L I   
Sbjct: 3741 MQDLEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDA 3798

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVH--------SKKSIYLESQHEGALPRLNQL-ED 1693
               D G Y C   NA G+A  S    +         S   +   ++ E     +  + +D
Sbjct: 3799 TKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELISDD 3858

Query: 1694 TSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753
            TS  ++     +     P FT+ +++  V E     F +R+I      ++VEW ++   I
Sbjct: 3859 TSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVI--SKAPIKVEWYKDDRLI 3916

Query: 1754 EAS-NRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLES 1812
             +   R T  HD    A+N+  V   D G YT    N+ G         V+SKA L +  
Sbjct: 3917 SSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGT--------VESKAYLNVLP 3968

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            + E   + I                     +PRF  +L    ++ EG +A  ECRI   P
Sbjct: 3969 EMEPEFEGI---------------------SPRFSVKLKNQ-EVIEGSTARLECRIVGSP 4006

Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
             P +R  WY + + L    +Y+   D    AL +  V  ED G Y   A N  G+ V + 
Sbjct: 4007 VPEVR--WYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTA 4064

Query: 1933 RLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEG 1992
             ++V+       D+  ES ++ +     +S+  +   +    + KP+    +++  V EG
Sbjct: 4065 DISVKHP-----DTDEESDIDAVDARPLESKPSKPKTE----IPKPEIVLGLRDRFVVEG 4115

Query: 1993 HPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMC 2052
              V      T  + P   V W+ +G+P+    R++ T   G  +L I      D G Y C
Sbjct: 4116 MSVRFNCRTT--SQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKC 4173

Query: 2053 KATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFL 2112
            + +N  G+A T++ + V        + L + R   +        P   +EE  G     +
Sbjct: 4174 EVSNVGGKAGTSAHLTV--------EELPKSRPSVVAS------PPRFQEELKG----VI 4215

Query: 2113 TALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD----FGYVA 2168
            T + +   L           V  I  P   I+W+ + +++  G R R   D    F  V+
Sbjct: 4216 TVVGTTTKLS----------VPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVS 4265

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA-QG 2227
            L I      D G Y C A NK G   ++ T+KV    +     +    L K    EA + 
Sbjct: 4266 LTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRM 4325

Query: 2228 HSTRIEVEEP--KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
                +    P  +  PP F+ +LR    + E +TA F C+V  +  P+   E+    K +
Sbjct: 4326 EDIPVAQSTPLKRGEPPEFIRKLR-DQFIQEKETARFVCRV--IGRPDPTYEWLRGDKPI 4382

Query: 2286 QSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344
                R+ I  D    +L+I  C  ED G Y   + N+ G  T+   +TV A    IS++
Sbjct: 4383 TDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPISKN 4441



 Score =  159 bits (387), Expect = 4e-38
 Identities = 239/1076 (22%), Positives = 407/1076 (37%), Gaps = 153/1076 (14%)

Query: 3820 PKEEP-IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878
            P+ EP      P+F  ++K+  V E    R ECR+     P++R  WYR+ + L    +Y
Sbjct: 3968 PEMEPEFEGISPRFSVKLKNQEVIEGSTARLECRIVGSPVPEVR--WYRDNEPLIESEKY 4025

Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938
            +   D    +L +  V  ED G Y   A N  G D   A IS K  PD   ++ +     
Sbjct: 4026 QMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKH-PDTDEESDIDAVDA 4084

Query: 3939 RSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLA 3998
            R      +E+   K  +E+               P  V  ++ +  +VE  + +F C+  
Sbjct: 4085 RP-----LESKPSKPKTEI-------------PKPEIVLGLRDRF-VVEGMSVRFNCRTT 4125

Query: 3999 PVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDE 4058
                P   V WF +G+PL    R+      G  ++        D+G Y C  +N+ G   
Sbjct: 4126 --SQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAG 4183

Query: 4059 TKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPD 4118
            T A +            +LPK   S+            +P +  EE K            
Sbjct: 4184 TSAHLTV---------EELPKSRPSVV----------ASPPRFQEELKG----------- 4213

Query: 4119 AVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPK-----TR 4173
             +TV  G   +    + GHP P + W  +   ++ G R +   D    F I        R
Sbjct: 4214 VITVV-GTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVR 4272

Query: 4174 QYDTGKIEVIXXXXXXXXXXXXXLKV--IPRHDDYRGVLKNAPRPWYDETTQYQR---TE 4228
              D G+ + +             +KV  +   D  +    + P+   DE  + +     +
Sbjct: 4273 LTDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDIPVAQ 4332

Query: 4229 TELEKTFEERQVLQ--RQGVIDHRPELK--PKVIKEPET--EWQQSVKRKKNEEYYNKLQ 4282
            +   K  E  + ++  R   I  +   +   +VI  P+   EW +  K   +   Y  + 
Sbjct: 4333 STPLKRGEPPEFIRKLRDQFIQEKETARFVCRVIGRPDPTYEWLRGDKPITDGGRYTIMS 4392

Query: 4283 ELENEQV-IKESRLR-ESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKK 4340
            + E + + I +  +  E  ++        T  T A+         ++ +     + ++K 
Sbjct: 4393 DDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARL-------TVEASRRPISKNIEKL 4445

Query: 4341 VTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTE-IEHKA---QT 4396
            + +   + + S S        +AK      E++G+ E   K       E +E +A   +T
Sbjct: 4446 LIKAASMDEESMSQA------LAKAIAESPELLGEPEPESKPADEPAKEPVEEEALLPET 4499

Query: 4397 QERVVEGPVKP---SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
              R  + P +P   S  P+F +K + CR+ E + ARF V+ +G P P + W+     I+ 
Sbjct: 4500 ASRADQTPDEPTAESGEPVFVQKPETCRLKEGDTARFNVKVNGSPEPFVDWFLGRRMIEE 4559

Query: 4454 SPDFQIHTFST-KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV--EEKRRQGRGG 4510
                +I      +  L+I  +  ED+ V+  VAEN  G+  C A L+V  EE        
Sbjct: 4560 DDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPT 4619

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL-----KNGKKVQPDIR------ 4559
             V P+          T              KP+    L     K G+ +  D++      
Sbjct: 4620 EVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLDVKLPQEYK 4679

Query: 4560 --------NKILEEDGTYTLL---------ILEAYPQDSGKYECVAINSAGEARCDAECV 4602
                    +K LE+D   T++         I     +D   Y+ VA N++G   CD E +
Sbjct: 4680 AEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVL 4739

Query: 4603 V----SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            V     +P   +  +  ++ +   PE +E  K   V E        +  G    +++W+K
Sbjct: 4740 VEERIKVPQIAN-IRGGSRLSQVAPEFMEQCKSTTVQENGTAIMEVRATGSQPLSIRWFK 4798

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV------ 4712
              + IK     +MS   +  TL+IS    +DEG Y CV  N AG     A L V      
Sbjct: 4799 NQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSD 4858

Query: 4713 ---------------TQPDQADNL-PAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
                           T+P ++    P++ TPL ++ V+ G     +     +    I+W 
Sbjct: 4859 GEDGATHGSPPKTRGTKPKKSSGAKPSIVTPLANMEVFSGDDVMLEVISGPEQVKKIEWF 4918

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            ++  LI + P F +  E     L I     +D G F C      G    SA+++V+
Sbjct: 4919 KDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVE 4974



 Score =  159 bits (385), Expect = 7e-38
 Identities = 105/402 (26%), Positives = 189/402 (47%), Gaps = 24/402 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-LI 4469
            P FT +M    V E  + +      G P P +KW R+  P+       + +   + + LI
Sbjct: 1963 PSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRVQGVTLI 2022

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            IR V   D  V+    +N+ G+   +  ++V ++        + P F    +NV    G+
Sbjct: 2023 IRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS-------IRPIFGQKMKNVEGRIGE 2075

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKYECVA 4588
             VR + +V GT    V + +  +++    R  I+EE+ G + L I    P+D+G+Y+C+A
Sbjct: 2076 DVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIA 2135

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            +N AGE          L   ++   PQ       P ++E      + +G   + S ++ G
Sbjct: 2136 VNGAGEVTSKGY----LHVEEELTIPQF--IGDVPGVVE------LVQGDNYDLSLEVRG 2183

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P P ++WY  ++LI  +   Q+S  + + T+ +     +D G Y+C A N+AG  +   
Sbjct: 2184 TPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQF 2243

Query: 4709 KLKVTQPDQADNLP--ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
             + V QP + +      ++ L+ + V EG+ A+ +  ++    PT++W R+G  + E+  
Sbjct: 2244 NINV-QPKRPEGTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRR 2302

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             +   E   A L+I  T+ ED GT+ C+     G+  TSA L
Sbjct: 2303 VRSTLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHL 2344



 Score =  157 bits (382), Expect = 2e-37
 Identities = 140/543 (25%), Positives = 229/543 (42%), Gaps = 39/543 (7%)

Query: 4289 VIKESRLRES-THQYAIPGDKVTSNTVAKSMAQR------YEDNLDQTEEVTEQRVQKKV 4341
            VIK++RL ++ T++     D  T++++A+   Q        ED+L     +  +RV+ KV
Sbjct: 357  VIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTKPEIEDSLRDVSALPGERVKFKV 416

Query: 4342 TQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEI-------EHKA 4394
                + P P      GK V    ++ T  E   D+  +  I   E T+         ++A
Sbjct: 417  RIGGK-PKPKVEWRKGKSVIEDGERFTIAEE-SDEVFSLIIQDLEETDAGRYKCVATNEA 474

Query: 4395 QTQERVVEGPVKPSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
               E + +  V      P F K  +   V E E         G+P P I+W ++   ++ 
Sbjct: 475  GEAESMAQLTVNEELIGPRFEKMKESFTVVEGESVELVARVTGKPAPEIEWTKDGKTVRK 534

Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513
            + +        +++L I +   +DS ++   A N+ GTA  +  L V+ K+ +G      
Sbjct: 535  TNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTA---- 590

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P      + V  T G    L   ++G     + WLKNG +V+   R K    DG   L I
Sbjct: 591  PEIVSELRPVEATEGDDAVLSCTISGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTI 650

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
                  D G Y C+  N  G A            +K K K     A A PE    LK   
Sbjct: 651  KTTRADDQGDYTCIVRNELGSAE-----------SKTKLKV---IAFARPEFRTKLKPVK 696

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE---YTLRISEAFPEDE 4690
              EG+ ++   K+ G P P ++WY+G  +I  S  F++    +E   Y+L IS+   +D 
Sbjct: 697  AVEGEEVQLDVKVEGYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGLYSLVISKLQLDDT 756

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G  K VA N++G+ T  A L+V + + A           IVV EG     + ++ +    
Sbjct: 757  GTIKVVATNASGKATSRADLEVKEREFAPEFEG-DEEGPIVVTEGNEVSIQLRVKANPNA 815

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             + W ++G  I E+    +   G    L I  +  EDTG + C A+   G+   S  + V
Sbjct: 816  DVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKV 875

Query: 4811 KSK 4813
            + K
Sbjct: 876  QVK 878



 Score =  157 bits (380), Expect = 3e-37
 Identities = 105/406 (25%), Positives = 175/406 (43%), Gaps = 21/406 (5%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P    K   P    E +     V   G+P P ++W++ +  +  S      +   K  + 
Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMT 1627

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +  + ++DS ++  VA N+ G++  + NL V++K+  G      P       +  V  G 
Sbjct: 1628 VSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVIGNA----PDIITHLISKEVKEGG 1683

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V L+  V+G    ++ W K+G +     R     +    ++   +A   D G+Y+CVA 
Sbjct: 1684 TVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVAT 1743

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N  G A+  A   V++P+     KP+ K    P E++E         G   +F  +I   
Sbjct: 1744 NPLGSAQSSARLTVTVPS-----KPEFKQKLRPLEVVE---------GSEAKFDVRIKSY 1789

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTA---DEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            P P V+WY+G   I  S   Q++      D Y+L I     ED   YKCVA+N AG+ T 
Sbjct: 1790 PKPEVEWYRGTTKITDSLRHQITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTC 1849

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
             A L V +  Q          + I+V EG        I  K  P + W ++G L+ ++  
Sbjct: 1850 RADLTVIEKQQPPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPEVSWYKDGRLVLDSIK 1909

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             +    G+ + L++ N   ED G++ C A    G V  +  + V S
Sbjct: 1910 QETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKVMS 1955



 Score =  155 bits (376), Expect = 8e-37
 Identities = 198/785 (25%), Positives = 308/785 (39%), Gaps = 98/785 (12%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827
            +P F++ +QDL E+ EG  A    ++  V +P   ++WYKD R I    R+   F   G 
Sbjct: 3734 KPSFLQRMQDL-EIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEEDGL 3790

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR---STVT-ADLGIPEQRRYIEK 883
              L I      D G Y     N  G+A  +A + +      S V+ ADL    ++   E 
Sbjct: 3791 CMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARES 3850

Query: 884  TXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRV 943
            T                   E    PEF   ++++  +KEGG   F +R+  I  + ++V
Sbjct: 3851 TIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNR-EVKEGGVTKFASRV--ISKAPIKV 3907

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003
            EW KD R + +     TF               HD   Y     N   +       T V 
Sbjct: 3908 EWYKDDRLISSDWPRHTF--------------EHDEDLYAMNISNV--KVADGGPYTFVV 3951

Query: 1004 KKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF 1063
                   S   G +E   YL          E        PRF   LK   +++EG +A  
Sbjct: 3952 -------SNKYGTVESKAYLNVLPEMEPEFEGI-----SPRFSVKLKN-QEVIEGSTARL 3998

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNA 1123
            E R+         V WY + + +  + + Q   D  + AL +  V  ED G Y  VARN 
Sbjct: 3999 ECRIVGSP--VPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNI 4056

Query: 1124 AGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPL 1183
            AG    +A ++V+   + + S I        R + ESK  +P  +I      KP  V  L
Sbjct: 4057 AGRDVCTADISVKHPDTDEESDIDA---VDARPL-ESKPSKPKTEI-----PKPEIVLGL 4107

Query: 1184 SNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHAT 1243
             +   V EG ++   CR      P   V WF +G+ +    R++     G  +L I    
Sbjct: 4108 RD-RFVVEGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCK 4164

Query: 1244 SADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVRE 1303
             AD G Y     N  G A TSA +           T  E    +  ++    R  ++++ 
Sbjct: 4165 LADAGIYKCEVSNVGGKAGTSAHL-----------TVEELPKSRPSVVASPPRFQEELKG 4213

Query: 1304 DITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
             ITV+                GT   L   +  +G  T  +EW+ + + +  G R R   
Sbjct: 4214 VITVV----------------GTTTKLSVPI--IGHPTPVIEWYKDDREVLEGGRIRFEQ 4255

Query: 1364 E----FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLE 1419
            +    F  V+L +  V   D G Y C A N+ G   +S  ++V   K+L  E     G  
Sbjct: 4256 DQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKV---KELDDEDSIQEGAM 4312

Query: 1420 KIQYLEDTSRYKKTDI-IDESVTIK----PRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
             +         +  DI + +S  +K    P F+ + +  + + E +   F C++    D 
Sbjct: 4313 SLPKSTSDEALRMEDIPVAQSTPLKRGEPPEFIRKLRD-QFIQEKETARFVCRVIGRPDP 4371

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                EW +  +P+T G R+  + D     L+I D   ED G+Y C + N  GTD  + RL
Sbjct: 4372 T--YEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARL 4429

Query: 1535 TCRST 1539
            T  ++
Sbjct: 4430 TVEAS 4434



 Score =  154 bits (373), Expect = 2e-36
 Identities = 117/412 (28%), Positives = 182/412 (44%), Gaps = 27/412 (6%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K  +P I  + ++   V E E A       G P P  +WYR++  ++ S   +    +  
Sbjct: 5    KGDRPQIL-QPLEGVDVKEDENAILSCTISGTPTPNAEWYRDSIRVRESRRIKSEVVNGM 63

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
            + L I+Q   ED   +  V  N  GTA   A L V           V PSFT   + V+ 
Sbjct: 64   ATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVP--------VKPSFTSKMKPVDA 115

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKY 4584
              GQ VR D  V G+   DV W K    +    R +I+E  +   TL+I E   +D+  Y
Sbjct: 116  EEGQEVRFDVHVKGSPKPDVVWYKGSTMIGTHERFQIVEAAEDHVTLVISEVKLEDAETY 175

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFS 4643
            + VA N  G+    A+  V             K     PE I+  +  I A  G  +  +
Sbjct: 176  KVVATNDVGKVTSRADLRV-------------KERQFAPEFIDEERGPIDATTGDEVTLT 222

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C + GKP P++ WYK  KL+  S    +  + +   + +  A PED   YKC A N  G+
Sbjct: 223  CSVSGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGK 282

Query: 4704 VTVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
             + A  +KV  P    + P+ T  L  +   EG+ ++   ++T K  PTI+WL+    + 
Sbjct: 283  ASRAFDVKVKAP--KGDAPSFTIDLTHVRAIEGEESKLVCKVTGKPAPTIEWLKGELPVT 340

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             +   +   E N A L+I +T   D GT+   A   +G   + A+L V+ ++
Sbjct: 341  TSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERS 392



 Score =  153 bits (372), Expect = 3e-36
 Identities = 182/772 (23%), Positives = 306/772 (39%), Gaps = 71/772 (9%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGF 1234
            +PVFVQ       + EG       ++   G P   V+WF   R +    R +    D G 
Sbjct: 4516 EPVFVQK-PETCRLKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGE 4572

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV-IERSDIVTD-TQNEQAIEQIQLLE 1292
             +L I+     D G Y   A N  GS    A + V IE  ++  + T+ E A  +    +
Sbjct: 4573 CSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTEVEPAPAEPTPTK 4632

Query: 1293 DAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP 1352
                 +K  + +      P F+  L + +  EG N+ L+ +L    +    V W+ + K 
Sbjct: 4633 IQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLDVKLPQ--EYKAEVAWYRDDKK 4690

Query: 1353 IKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
            ++  HR       D   L +  V  +D  VY   ATN  G   TSC   V+ ++ +    
Sbjct: 4691 LEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASG--TTSCDCEVLVEERI---- 4744

Query: 1413 QHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVT 1472
                 + +I  +   SR  +         + P F+ + KS      G  +    ++    
Sbjct: 4745 ----KVPQIANIRGGSRLSQ---------VAPEFMEQCKSTTVQENGTAI---MEVRATG 4788

Query: 1473 DSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC 1532
               L + WFKN Q +  G R +   D  +  L I  +  +D G+Y C   N  GT +   
Sbjct: 4789 SQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEA 4848

Query: 1533 RLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEG 1592
             LT          +  E G       + R    +       +   P   T L N+E+  G
Sbjct: 4849 LLTVEPMV-----SDGEDGATHGSPPKTRGTKPKKS-----SGAKPSIVTPLANMEVFSG 4898

Query: 1593 QRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTC 1652
                 E  +I   +   K+EW+ +N+ ++   RFT T+      L I +   +D G + C
Sbjct: 4899 DDVMLE--VISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKC 4956

Query: 1653 RAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPV 1712
              +N  G A  S   +V   +  Y ES  + A  R       ++ +R  ++D +   A  
Sbjct: 4957 VLLNDFGIASCSAEILVEEDEESYSESSADEATDR------NARIERRRSRDSIC--ALE 5008

Query: 1713 FTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL--TTMHDFGYVAL 1770
            F   +KD  V +    HF+ R+   G P+ +V W ++   +  S R+   +  + G  +L
Sbjct: 5009 FQQELKDREVLDGDTIHFDVRI--TGRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSL 5066

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             +K    +D G Y C A N  G     + L V+      +  + ++   K          
Sbjct: 5067 LIKKATLDDEGDYRCVAANPAGTISCQAELLVE-----DVPEEEDTTDSKPAPATAPKPA 5121

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQS 1889
            +R+E       +AP F   L   T + +G +A ++ R+  +P P+  V W    K +  +
Sbjct: 5122 KRKE-------EAPVFTALLKDRT-IKDGDAARFDARVIGFPTPD--VTWLREDKQITPN 5171

Query: 1890 GHRYRTSNDFGFAALDILTVYG-EDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             H +  +   G     ++T  G +DSG Y C A N+ GQ  +   L V+  E
Sbjct: 5172 SHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEGPE 5223



 Score =  153 bits (371), Expect = 3e-36
 Identities = 107/413 (25%), Positives = 180/413 (43%), Gaps = 26/413 (6%)

Query: 4405 VKPSKP----PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            V+P +P    P     ++   V E EQA  E    G P P ++WYR+   +K S   +  
Sbjct: 2247 VQPKRPEGTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRRVRST 2306

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
              +  + L+I + + ED   +     N  G    SA+L +    R        P F    
Sbjct: 2307 LENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNIIVATR--------PEFKEKL 2358

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI--LEEDGTYTLLILEAYP 4578
              V VT G   + + +V G    +V W     ++  + R +I  ++E G Y+L + E   
Sbjct: 2359 TKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQ 2418

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
            +D+G Y+C+A+N AG++ C A+  V+    +  P+ +T     P          +V EG 
Sbjct: 2419 EDAGMYKCIAVNKAGKSTCRADLEVN--ERQFAPEFETGEERGPI---------VVPEGG 2467

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
                   +   P P V WYK  K    +    +    + + L+I+ A  ED G YKC A 
Sbjct: 2468 ETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEAR 2527

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
            N  G    +  ++V  P      P  L  L+ +   EG+  + + +++ K +PTI WL++
Sbjct: 2528 NKLGFADKSFTIRVEVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKD 2587

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            G +       +   +G+   L I +    D G + C A  ++G   +SA+L V
Sbjct: 2588 GLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTV 2640



 Score =  153 bits (370), Expect = 4e-36
 Identities = 112/403 (27%), Positives = 178/403 (44%), Gaps = 24/403 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--L 4468
            P F +K+    V E ++A+FEV   G P P ++WY  +  I +   F+I +        L
Sbjct: 2352 PEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSL 2411

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN--VNVT 4526
             + +V  ED+ ++  +A N+ G + C A+L V E++         P F    +   + V 
Sbjct: 2412 TVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQ-------FAPEFETGEERGPIVVP 2464

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             G    L   +       V W K+GK    +IR  +     T+ L I  A  +DSG Y+C
Sbjct: 2465 EGGETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKC 2524

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
             A N  G A  D    + +    + PKP        P I++ L+     EG+AI+  C++
Sbjct: 2525 EARNKLGFA--DKSFTIRV----EVPKP----TGEEPTILQRLQPVDTIEGEAIKMECRV 2574

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             GKP PT+ W K   +       +     D  TL I +    DEG Y+C A NS+G    
Sbjct: 2575 SGKPEPTITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHS 2634

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
            +A+L V + +    +  L  L+D+    G+ A FK +++    P +QW R    I     
Sbjct: 2635 SAELTVLEREARPRI--LEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGH 2692

Query: 4767 FQMIHEGNNAV-LLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            + +  EG     L I     ED G +       +G+V ++A L
Sbjct: 2693 YIVRDEGRGYFSLTIEYIDYEDEGAYKAVVINDSGEVSSTAVL 2735



 Score =  152 bits (369), Expect = 6e-36
 Identities = 132/459 (28%), Positives = 199/459 (43%), Gaps = 59/459 (12%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F ++ +   V E+  A  EV   G     I+W++    IK     ++ +      L I
Sbjct: 4763 PEFMEQCKSTTVQENGTAIMEVRATGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKI 4822

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV------------------ 4512
              V  +D  ++  V  N+ GTA C A L VE     G  G                    
Sbjct: 4823 SPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPPKTRGTKPKKSSGA 4882

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKILEEDGTYTL 4571
             PS      N+ V SG  V L+  ++G + +  + W K+ + ++   R  +  ED  +TL
Sbjct: 4883 KPSIVTPLANMEVFSGDDVMLEV-ISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTL 4941

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVV----------SLPATKDK----PKPQTK 4617
             I  A   D G ++CV +N  G A C AE +V          S     D+     + +++
Sbjct: 4942 TIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIERRRSR 5001

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK--YFQMSRTA 4675
             +    E  + LKD+ V +G  I F  +I G+P P V WYK DK +  SK   F      
Sbjct: 5002 DSICALEFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIFVSEPET 5061

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADN-----LPALTP--- 4726
              Y+L I +A  +DEGDY+CVA N AG ++  A+L V   P++ D       PA  P   
Sbjct: 5062 GLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEEDTTDSKPAPATAPKPA 5121

Query: 4727 ------------LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI-PET-PDFQMIHE 4772
                        L+D  + +G  A+F  ++     P + WLRE   I P + P  + +HE
Sbjct: 5122 KRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALHE 5181

Query: 4773 GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            G    LLI     +D+G + C A  +AGQ  T   L V+
Sbjct: 5182 GEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVE 5220



 Score =  151 bits (366), Expect = 1e-35
 Identities = 164/635 (25%), Positives = 240/635 (37%), Gaps = 74/635 (11%)

Query: 382  RIEISEKALAPQFVKVCQDR--DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
            R+ + EK + P F +   D   +V EG   +   ++ G+P P V WF   RQ +   N K
Sbjct: 3615 RLAVKEKMVTPSFAEGDADEPCEVWEGAPIKLIVQIKGKPAPTVEWFKEKRQAKRLKNVK 3674

Query: 440  ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV----------V 489
             L  E   H L+I      DSG   C A N +G      ++ V E++ V          V
Sbjct: 3675 -LFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVNEQKVVMRRQPIPPGAV 3733

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH-TDGGASTL 548
             P F++R   L + EG    L  R  G P P I W KD   I     +     + G   L
Sbjct: 3734 KPSFLQRMQDLEIVEGSAARLCVRVQGVPEPEIDWYKDNRVIREGGRVEFEFEEDGLCML 3793

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXX 608
             I  A  SD   Y+C   N AG     A L+               L    +        
Sbjct: 3794 VIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDA-DLDFAARKEARESTI 3852

Query: 609  XXXXXYLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTM 668
                      E+      P EE     PP+F + L++    EGG   F +R+  +    +
Sbjct: 3853 ELISDDTSDEEKTEG--APKEEGA---PPEFTLVLRNREVKEGGVTKFASRV--ISKAPI 3905

Query: 669  KIEWLKNGQSIEAS-SRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLH 727
            K+EW K+ + I +   R T        ++++ ++ + D G YT    +  G  E+KA L+
Sbjct: 3906 KVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESKAYLN 3965

Query: 728  VTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRN 787
            V P    E     P             K ++QE IE                     G  
Sbjct: 3966 VLPEMEPEFEGISPRF---------SVKLKNQEVIE---------------------GST 3995

Query: 788  AHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
            A  E ++  V  P   V WY+D  P+  S +     +  + +L +  +  ED G Y   A
Sbjct: 3996 ARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVA 4053

Query: 848  VNKLGEAISTASIRVAARST-VTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPEST 906
             N  G  + TA I V    T   +D+   + R    K                  +P   
Sbjct: 4054 RNIAGRDVCTADISVKHPDTDEESDIDAVDARPLESKP-----------SKPKTEIP--- 4099

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
             KPE    ++D+  + EG    F  R          V W KDG+P+ +  R       G 
Sbjct: 4100 -KPEIVLGLRDRF-VVEGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGA 4155

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +LTIK   + DAG Y C   N  G+A TSA+LT+
Sbjct: 4156 QSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTV 4190



 Score =  151 bits (365), Expect = 2e-35
 Identities = 179/786 (22%), Positives = 312/786 (39%), Gaps = 69/786 (8%)

Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484
            E  SR  +T     + + +P FV +P++   + EG    F  K+    +    V+WF   
Sbjct: 4498 ETASRADQTPDEPTAESGEPVFVQKPETCR-LKEGDTARFNVKVNGSPEPF--VDWFLGR 4554

Query: 1485 QPVTIGHRFRPIH-DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIV 1543
            + +    R R    D G  +L I+D+  ED+G+Y C A N  G+      L      D +
Sbjct: 4555 RMIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDEL 4614

Query: 1544 RS--TQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
             +  T+ E    +    + +++  +    +      P+  + L + ++KEG+    + +L
Sbjct: 4615 DAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLDVKL 4674

Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
                +   +V WY ++K L+   R T         L I     +D   Y   A NA G  
Sbjct: 4675 --PQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTT 4732

Query: 1662 VTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIR 1721
                  +V  +  +   +   G   RL+Q+                  AP F    K   
Sbjct: 4733 SCDCEVLVEERIKVPQIANIRGG-SRLSQV------------------APEFMEQCKSTT 4773

Query: 1722 VAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSG 1781
            V EN  A  E R    G   L + W +N   I+   R+    D  +  L +  V  +D G
Sbjct: 4774 VQENGTAIMEVRA--TGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEG 4831

Query: 1782 TYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVN 1841
             Y C   N+ G A   + L V+   S   +     +  K +  +             +  
Sbjct: 4832 LYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPPKTRGTKPKK----------SSG 4881

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
              P  +T L      S G     E  +   P+   ++EW+ + ++++   R+  +++   
Sbjct: 4882 AKPSIVTPLANMEVFS-GDDVMLE--VISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTR 4938

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
              L I T   +D G + C  +N+ G A  S  + V+  E    +S  + A ++      +
Sbjct: 4939 HTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDR------N 4992

Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021
            +R +R    DS      +F + +K+ EV +G  +H +  +T    P  +V WY + + + 
Sbjct: 4993 ARIERRRSRDSICA--LEFQQELKDREVLDGDTIHFDVRIT--GRPEPKVVWYKDDKELV 5048

Query: 2022 QGHR--FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDT 2079
            +  R  F +  + G  +L I  A  +D G Y C A N  G         +  ++ L ++ 
Sbjct: 5049 ESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAG--------TISCQAELLVED 5100

Query: 2080 LDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDP 2139
            + E+      +      PKP + ++  + PVF TAL     +K+GD A F+ RV  I  P
Sbjct: 5101 VPEEEDTTDSKPAPATAPKPAKRKE--EAPVF-TALLKDRTIKDGDAARFDARV--IGFP 5155

Query: 2140 HLTIDWFHNGQKIRA-GHRY-RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
               + W    ++I    H + +  H+    +L I     +DSG Y C A N  G+     
Sbjct: 5156 TPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVG 5215

Query: 2198 TLKVAG 2203
             L V G
Sbjct: 5216 HLFVEG 5221



 Score =  150 bits (363), Expect = 3e-35
 Identities = 106/343 (30%), Positives = 156/343 (45%), Gaps = 35/343 (10%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +KP I T  +    VF  +    EV    E +  I+W+++N  I++ P F + +  T+  
Sbjct: 4882 AKPSIVTP-LANMEVFSGDDVMLEVISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHT 4940

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE--------------------KRRQG 4507
            L I     +D  +F  V  N  G A CSA ++VEE                    +RR+ 
Sbjct: 4941 LTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIERRRS 5000

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED- 4566
            R  I    F    ++  V  G  +  D ++TG     V W K+ K++    R   + E  
Sbjct: 5001 RDSICALEFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIFVSEPE 5060

Query: 4567 -GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV-SLPATKD----KPKPQT---- 4616
             G Y+LLI +A   D G Y CVA N AG   C AE +V  +P  +D    KP P T    
Sbjct: 5061 TGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEEDTTDSKPAPATAPKP 5120

Query: 4617 -KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS--R 4673
             K     P     LKD+ + +G A  F  +++G P P V W + DK I P+ +  M    
Sbjct: 5121 AKRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALH 5180

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
              + ++L I+E   +D G YKC+A NSAG+ T    L V  P+
Sbjct: 5181 EGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEGPE 5223



 Score =  149 bits (362), Expect = 4e-35
 Identities = 113/414 (27%), Positives = 180/414 (43%), Gaps = 33/414 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I T  +    V E      E    G+P P I+WY++   ++ +   ++ T    S+  
Sbjct: 1668 PDIITHLISK-EVKEGGTVTLECTVSGKPAPNIEWYKDG--LRFTATRRVMTTFDGSVAS 1724

Query: 4470 IRQVFVE--DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            +     +  D   +  VA N  G+A+ SA L V    +        P F    + + V  
Sbjct: 1725 VTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSK--------PEFKQKLRPLEVVE 1776

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE---DGTYTLLILEAYPQDSGKY 4584
            G   + D ++      +V W +   K+   +R++I E    D TY+L+IL    +D+  Y
Sbjct: 1777 GSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQITEPYEGDDTYSLIILNTTMEDAAMY 1836

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
            +CVA N AG+  C A+  V      +K +P T   +   + I      IV EG  +  S 
Sbjct: 1837 KCVAFNEAGKTTCRADLTVI-----EKQQPPTFLGDDGTQTI------IVKEGDDLNISA 1885

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             I GKP P V WYK  +L+  S   +  +  DE  L +  A  ED G YKC A N  G V
Sbjct: 1886 TIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTV 1945

Query: 4705 TVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
            T    +KV         P+ T  +  + V EG   +    I+   KPT++W R+G  IP 
Sbjct: 1946 TKTYNVKVMSTAPEGQAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVKWTRDG--IPV 2003

Query: 4764 TPDFQMIHEGN---NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
              D+++  + +      L+I N    D G + C      G   T+ +++V  ++
Sbjct: 2004 FEDYRISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS 2057



 Score =  149 bits (361), Expect = 5e-35
 Identities = 208/883 (23%), Positives = 346/883 (39%), Gaps = 115/883 (13%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576
            P E+WEG  A  +  V   G P+   EW+    + K     +   +     L I      
Sbjct: 3635 PCEVWEG--APIKLIVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPE 3692

Query: 2577 DAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDT 2636
            D+G Y C+A N AG               ++++            ++  M + P   +  
Sbjct: 3693 DSGNYRCQATNDAGTVTKTFKV-------VVNE------------QKVVMRRQP---IPP 3730

Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            G  + P F   ++  + +VEG    L  +V+   +P  +I+W+K+   +  G R++  F+
Sbjct: 3731 GAVK-PSFLQRMQDLE-IVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFE 3786

Query: 2697 F-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE-----------DRHWLLGES 2744
              GL  L I      D G Y C  +N  G+A  +A + IE           D  +   + 
Sbjct: 3787 EDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKE 3846

Query: 2745 LHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPT 2804
                +++ I                      F   L N   KEG    F   V  S+ P 
Sbjct: 3847 ARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVI-SKAP- 3904

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            +K+EW+ +++ + S        D+        HT+E D  +Y    +N K      G   
Sbjct: 3905 IKVEWYKDDRLISS--------DWP------RHTFEHDEDLYAMNISNVK---VADGGPY 3947

Query: 2865 CTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLV 2924
                 N Y   +    KA L  + + E            P+ E   P + + +  + +++
Sbjct: 3948 TFVVSNKYGTVE---SKAYLNVLPEME------------PEFEGISPRFSVKLKNQ-EVI 3991

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984
            EG    LE ++     P+++  WY + + L +  ++++  D     L + DV E D G Y
Sbjct: 3992 EGSTARLECRIVGSPVPEVR--WYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHY 4049

Query: 2985 TCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDT 3044
               A N  G         CT+  ++    +HP  T+    I  ++    +    +P  + 
Sbjct: 4050 KAVARNIAGRDV------CTADISV----KHPD-TDEESDIDAVDARPLESKPSKPKTEI 4098

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
             +P E     +D   + EG    +      T      + WF +G+ + +  R       G
Sbjct: 4099 PKP-EIVLGLRDRF-VVEGMSVRFNCRT--TSQPKPYVTWFKDGQPLASYGRYEVTSVAG 4154

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL--ECVDKSK----GQKPRFTTHIQNI 3158
               L I   K  D+G Y C  +N  G+A  S  L  E + KS+       PRF    + +
Sbjct: 4155 AQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPSVVASPPRFQ---EEL 4211

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD----FGFVVLDIAYT 3214
            +G+        + +V  +  P   IEWY + + +    RI+   D    F  V L I   
Sbjct: 4212 KGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDV 4271

Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
            +  D G Y C A NK G DF+ AT+          +S+Q  +++  +         +  P
Sbjct: 4272 RLTDEGRYKCVAKNKSGTDFSSATVKVKELDDE--DSIQEGAMSLPKSTSDEALRMEDIP 4329

Query: 3275 ---STP--SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329
               STP    EPP+FI +++D   + E ++A F  R++   DP    EW    K +  G 
Sbjct: 4330 VAQSTPLKRGEPPEFIRKLRDQF-IQEKETARFVCRVIGRPDPTY--EWLRGDKPITDGG 4386

Query: 3330 RYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            RY    D     L+I  C  E+ G Y+CV+TN  G D+T A L
Sbjct: 4387 RYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARL 4429



 Score =  145 bits (352), Expect = 7e-34
 Identities = 224/952 (23%), Positives = 370/952 (38%), Gaps = 138/952 (14%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            TVEW+   +Q      ++ + +     L I     EDSG Y   A N AG    +  + V
Sbjct: 3657 TVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVV 3716

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
                                   E K V     I      KP F+Q + +   V EG   
Sbjct: 3717 N----------------------EQKVVMRRQPIPP-GAVKPSFLQRMQDLEIV-EGSAA 3752

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK-TYYDFGFVALDIIHATSADTGEYTVRA 1254
             L  R++  G P   ++W+ + R +  G R +  + + G   L I  AT +D G Y    
Sbjct: 3753 RLCVRVQ--GVPEPEIDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVV 3810

Query: 1255 VNHLGSAHTSAIVRV--------IERSDIVTDTQNEQAIEQIQLL-EDAARRTKQVREDI 1305
             N  G A  SA + +        +  +D+    + E     I+L+ +D +   K      
Sbjct: 3811 SNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELISDDTSDEEKTEGAPK 3870

Query: 1306 TVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
                 P+F+  L N E  EG       R+  +    ++VEW+ + + I +     P + F
Sbjct: 3871 EEGAPPEFTLVLRNREVKEGGVTKFASRV--ISKAPIKVEWYKDDRLISSDW---PRHTF 3925

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
            ++           D  +Y    +N +  A       V++ K   +ES+  + L  +  +E
Sbjct: 3926 EH-----------DEDLYAMNISN-VKVADGGPYTFVVSNKYGTVESK--AYLNVLPEME 3971

Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485
                        E   I PRF  + K+ E VIEG     EC++  V     +V W+++ +
Sbjct: 3972 P-----------EFEGISPRFSVKLKNQE-VIEGSTARLECRI--VGSPVPEVRWYRDNE 4017

Query: 1486 PVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRS 1545
            P+    +++   D  + AL + D+  ED G Y   A N+ G D  +  ++ +        
Sbjct: 4018 PLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHP-----D 4072

Query: 1546 TQNEAGLEQIQV--LEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIP 1603
            T  E+ ++ +    LE +    +T++        P     L++  + EG    F  R   
Sbjct: 4073 TDEESDIDAVDARPLESKPSKPKTEI------PKPEIVLGLRDRFVVEGMSVRFNCRT-- 4124

Query: 1604 VSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT 1663
             S     V W+ + +PL S  R+  T+  G  +L I  C   D+G Y C   N  G+A T
Sbjct: 4125 TSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGT 4184

Query: 1664 SGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVA 1723
            S    V               LP+              ++  V+   P F   +K +   
Sbjct: 4185 SAHLTVEE-------------LPK--------------SRPSVVASPPRFQEELKGVITV 4217

Query: 1724 ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD----FGYVALNMKYVNPED 1779
                      +I  G P   +EW ++   +    R+    D    F  V+L ++ V   D
Sbjct: 4218 VGTTTKLSVPII--GHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTD 4275

Query: 1780 SGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVA 1839
             G Y C A N+ G   +S+T  V+ K     +S  E A+   +   D +   R ED+ VA
Sbjct: 4276 EGRYKCVAKNKSGTDFSSAT--VKVKELDDEDSIQEGAMSLPKSTSDEA--LRMEDIPVA 4331

Query: 1840 VN------QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
             +      + P FI +L     + E ++A + CR+   PDP    EW    K +  G RY
Sbjct: 4332 QSTPLKRGEPPEFIRKLRDQF-IQEKETARFVCRVIGRPDPT--YEWLRGDKPITDGGRY 4388

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
               +D     L+I     ED G Y C + N+ G   ++ RL V++    I     E  L 
Sbjct: 4389 TIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPI-SKNIEKLLI 4447

Query: 1954 KIQYLEDDSRYKRAVQDDSFVVEKPQ-FGKP---IKNAEVTEGHPVHLEATL 2001
            K   ++++S  +   +    + E P+  G+P    K A+     PV  EA L
Sbjct: 4448 KAASMDEESMSQALAK---AIAESPELLGEPEPESKPADEPAKEPVEEEALL 4496



 Score =  142 bits (345), Expect = 5e-33
 Identities = 129/532 (24%), Positives = 216/532 (40%), Gaps = 46/532 (8%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PP F +  ++    +   A+F  ++ G P P   W R   P+ +  +Y++  +++    +
Sbjct: 4341 PPEFIRKLRDQFIQEKETARFVCRVIGRPDPTYEWLRGDKPITDGGRYTIMSDDE--GQT 4398

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I      DEG Y C + N  G    +  +  E               +  S   E  +
Sbjct: 4399 LEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPISKNIEKLLIKAASMDEESMS 4458

Query: 191  YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
               Q      +   + +         + +  K    E  LL E + R   T         
Sbjct: 4459 ---QALAKAIAESPELLGEPEPESKPADEPAKEPVEEEALLPETASRADQTP-------- 4507

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
                  D        P   QKP   +L+EG  A+F V+++G+P P V WF  G+R+I  +
Sbjct: 4508 ------DEPTAESGEPVFVQKPETCRLKEGDTARFNVKVNGSPEPFVDWFL-GRRMIEED 4560

Query: 311  KHEIITTHN--HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
                I   +    +L + +  + D+G Y  +AEN +G I     L V+   +    +   
Sbjct: 4561 DRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTE 4620

Query: 369  QYITDTQQRETEERIEIS-----EKALAPQ--FVKVCQDRDVTEGKMTRFDCRVTGRPYP 421
                  +   T+ + E+S     E A AP+  F     D+ V EG+    D ++      
Sbjct: 4621 VEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLDVKLPQEYKA 4680

Query: 422  EVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            EV W+ +D+++ DD  H+I +  +G+ H L I  V++ D  V   VA N SG T+  C +
Sbjct: 4681 EVAWYRDDKKLEDD--HRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEV 4738

Query: 481  NVIEKEQV--------------VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
             V E+ +V              VAP+F+E+  +  V+E    ++  RA G+    I W K
Sbjct: 4739 LVEERIKVPQIANIRGGSRLSQVAPEFMEQCKSTTVQENGTAIMEVRATGSQPLSIRWFK 4798

Query: 527  DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +   I     +++ +DG   TL I   +  D   Y C   N AG+    A L
Sbjct: 4799 NQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALL 4850



 Score =  142 bits (344), Expect = 6e-33
 Identities = 126/489 (25%), Positives = 203/489 (41%), Gaps = 63/489 (12%)

Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
            + S +   +E KA         P      P F+ K++   V E   AR E    G P+P 
Sbjct: 3950 VVSNKYGTVESKAYLNVLPEMEPEFEGISPRFSVKLKNQEVIEGSTARLECRIVGSPVPE 4009

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV- 4500
            ++WYR+N P+  S  +Q+        LI++ V  ED   + AVA N  G   C+A++ V 
Sbjct: 4010 VRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVK 4069

Query: 4501 ------------------EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP 4542
                              E K  + +  I  P   L  ++  V  G  VR + + T    
Sbjct: 4070 HPDTDEESDIDAVDARPLESKPSKPKTEIPKPEIVLGLRDRFVVEGMSVRFNCRTTSQPK 4129

Query: 4543 IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
              V W K+G+ +    R ++    G  +L I +    D+G Y+C   N  G+A   A   
Sbjct: 4130 PYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLT 4189

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
            V     ++ PK +     +PP   E LK  I   G   + S  I+G P P ++WYK D+ 
Sbjct: 4190 V-----EELPKSRPSVVASPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDRE 4244

Query: 4663 IKPSKYFQMSRTAD-EYT---LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718
            +      +  +  +  +T   L I +    DEG YKCVA N +G    +A +KV + D  
Sbjct: 4245 VLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVKELDDE 4304

Query: 4719 D-------NLPALTP-----LRDIVVYE------GQPAQFKTQITSKI------------ 4748
            D       +LP  T      + DI V +      G+P +F  ++  +             
Sbjct: 4305 DSIQEGAMSLPKSTSDEALRMEDIPVAQSTPLKRGEPPEFIRKLRDQFIQEKETARFVCR 4364

Query: 4749 -----KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                  PT +WLR    I +   + ++ +     L I +   ED G + C +T ++G   
Sbjct: 4365 VIGRPDPTYEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDT 4424

Query: 4804 TSAKLVVKS 4812
            T+A+L V++
Sbjct: 4425 TTARLTVEA 4433



 Score =  142 bits (344), Expect = 6e-33
 Identities = 124/492 (25%), Positives = 214/492 (43%), Gaps = 54/492 (10%)

Query: 4373 VGDKEITRKITSTETTEIEHKAQTQERVVEGPVK----PSKPPIFTKKMQPCRVFEHEQA 4428
            + + E+  + T  E    E      +  V  P K    P+  P+F  ++   +V E E  
Sbjct: 4609 IEEDELDAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENL 4668

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
              +V+   E    + WYR++  +++     I        L I  V ++D AV+  VA N 
Sbjct: 4669 SLDVKLPQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNA 4728

Query: 4489 GGTAKCSANLVVEEKRRQG-----RGGI----VPPSFTLTAQNVNVTSGQLVRLDTKVTG 4539
             GT  C   ++VEE+ +       RGG     V P F    ++  V       ++ + TG
Sbjct: 4729 SGTTSCDCEVLVEERIKVPQIANIRGGSRLSQVAPEFMEQCKSTTVQENGTAIMEVRATG 4788

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDA 4599
            ++P+ + W KN + ++   R K+  +    TL I     +D G Y CV  N AG A C+A
Sbjct: 4789 SQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEA 4848

Query: 4600 ----ECVVSLP---ATKDKPKPQT------KAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
                E +VS     AT   P P+T      K++ A P I+ PL +  V  G  +      
Sbjct: 4849 LLTVEPMVSDGEDGATHGSP-PKTRGTKPKKSSGAKPSIVTPLANMEVFSGDDVMLEVIS 4907

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
              + +  ++W+K ++LI+    F ++     +TL I+ A  +DEG +KCV  N  G  + 
Sbjct: 4908 GPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASC 4967

Query: 4707 AAKLKVTQPDQA----------------------DNLPAL---TPLRDIVVYEGQPAQFK 4741
            +A++ V + +++                      D++ AL     L+D  V +G    F 
Sbjct: 4968 SAEILVEEDEESYSESSADEATDRNARIERRRSRDSICALEFQQELKDREVLDGDTIHFD 5027

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAA 4799
             +IT + +P + W ++   + E+     + E    +  LLI     +D G + C A   A
Sbjct: 5028 VRITGRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPA 5087

Query: 4800 GQVETSAKLVVK 4811
            G +   A+L+V+
Sbjct: 5088 GTISCQAELLVE 5099



 Score =  142 bits (343), Expect = 8e-33
 Identities = 116/460 (25%), Positives = 198/460 (43%), Gaps = 32/460 (6%)

Query: 4380 RKITSTETTEIEHKAQTQERVVEG-PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438
            RK     T E+     + E   EG P +   PP FT  ++   V E    +F      + 
Sbjct: 3844 RKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVISKA 3903

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILI---IRQVFVEDSAVFAAVAENRGGTAKCS 4495
               ++WY+++  I  S D+  HTF     L    I  V V D   +  V  N+ GT +  
Sbjct: 3904 PIKVEWYKDDRLI--SSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESK 3961

Query: 4496 ANL-VVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            A L V+ E   +  G  + P F++  +N  V  G   RL+ ++ G+   +V W ++ + +
Sbjct: 3962 AYLNVLPEMEPEFEG--ISPRFSVKLKNQEVIEGSTARLECRIVGSPVPEVRWYRDNEPL 4019

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-- 4612
                + ++ ++   + L++ +   +D G Y+ VA N AG   C A+  V  P T ++   
Sbjct: 4020 IESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHPDTDEESDI 4079

Query: 4613 ----------KPQTKAANAP-PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
                      KP       P PEI+  L+D+ V EG ++ F+C+   +P P V W+K  +
Sbjct: 4080 DAVDARPLESKPSKPKTEIPKPEIVLGLRDRFVVEGMSVRFNCRTTSQPKPYVTWFKDGQ 4139

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADN 4720
             +     ++++  A   +L I +    D G YKC   N  G+   +A L V + P    +
Sbjct: 4140 PLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPS 4199

Query: 4721 LPALTP-----LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE--TPDFQMIHEG 4773
            + A  P     L+ ++   G   +    I     P I+W ++   + E     F+   EG
Sbjct: 4200 VVASPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEG 4259

Query: 4774 NNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               +  L I +    D G + C A   +G   +SA + VK
Sbjct: 4260 RFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVK 4299



 Score =  140 bits (340), Expect = 2e-32
 Identities = 120/510 (23%), Positives = 208/510 (40%), Gaps = 28/510 (5%)

Query: 4308 KVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQ 4367
            K TS        + +    +  ++  +  V K+V  K    +P   +++  +V       
Sbjct: 1269 KTTSRADLTVKEREFAPEFETRDDTIDSEVNKEVEIKVTTGEPIRDSIN-TDVRAIGDSH 1327

Query: 4368 TQKEVVGDKEITRKITSTETTEIEHKAQTQERVV---EGPVKPSKPPIFTKKMQPCRVFE 4424
            T   +V  K     +   + T     A     V      P    + PI  +K+Q   + E
Sbjct: 1328 TCF-IVRAKLSDAGVYKCQATNAAGSASRSWEVKVKQSAPKTTGEEPIIIRKLQAQEIDE 1386

Query: 4425 HEQARFEVEFDG-EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
               A    +    +P P IKW R+   I+ +   ++        L IR   ++D  V+  
Sbjct: 1387 GSTANLVCKVTAAKPEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKV 1446

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543
               N  GTA  +  ++V E   +       P F    + V+   G+  R + K++     
Sbjct: 1447 TLTNEYGTASSTCRVLVNEVGSR-------PIFQQKLKAVSTIEGESTRFEVKLSAMPRP 1499

Query: 4544 DVYWLKNGKKVQPDIRNKILEED--GTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
             V W K+  ++    R  I EE+  G Y L+I +   +D+G Y+ VA N+ G+    A  
Sbjct: 1500 TVEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALL 1559

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V+   T   P+   KA         P++     EG  +E + ++ GKP P ++W+K D+
Sbjct: 1560 RVNEVLT--VPEFMDKAEG-------PIEK---TEGDDLELTVRVRGKPQPELEWFKYDR 1607

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
             +  S         +++T+ +S+   +D G Y+CVA N AG  +    L V +     N 
Sbjct: 1608 TLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVIGNA 1667

Query: 4722 P-ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
            P  +T L    V EG     +  ++ K  P I+W ++G     T       +G+ A +  
Sbjct: 1668 PDIITHLISKEVKEGGTVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTF 1727

Query: 4781 GNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             +    D G + C AT   G  ++SA+L V
Sbjct: 1728 TDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757



 Score =  140 bits (340), Expect = 2e-32
 Identities = 172/725 (23%), Positives = 284/725 (39%), Gaps = 63/725 (8%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT--YDG--MYH 4166
            P F      + V EG  A+F  R+  +PKP V W      I +  R+++T  Y+G   Y 
Sbjct: 1763 PEFKQKLRPLEVVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQITEPYEGDDTYS 1822

Query: 4167 FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQR 4226
              I  T   D    + +             L VI +        +  P    D+ TQ   
Sbjct: 1823 LIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK--------QQPPTFLGDDGTQ--- 1871

Query: 4227 TETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPE---TEWQQSVKRKKNEEY---YN- 4279
              T + K   E   L     I  +P  +    K+        +Q  +++ +E +   +N 
Sbjct: 1872 --TIIVK---EGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNA 1926

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339
            K+++  + +    ++L   T  Y +   KV S T  +  A  +   + Q  EV E    K
Sbjct: 1927 KMEDAGSYKCEANNKLGTVTKTYNV---KVMS-TAPEGQAPSFTSEMSQV-EVDEGGEVK 1981

Query: 4340 KVTQKPRIPDPS-ESTVHGKEV-HVAKQKQTQKEVVGDKEITRKITSTE------TTEIE 4391
                    P P+ + T  G  V    +       V G   I R +T  +      T + +
Sbjct: 1982 LYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQ 2041

Query: 4392 HKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI 4451
            H + T    V    +  +P IF +KM+       E  RFE++ +G P+P + ++RE+  I
Sbjct: 2042 HGSTTTTVQVIVTQRSIRP-IFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQI 2100

Query: 4452 KNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG 4510
             +   + I    +   +L IR    ED+  +  +A N  G       L VEE+       
Sbjct: 2101 YDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEEL------ 2154

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             +P         V +  G    L  +V GT   ++ W  N + +    R ++       T
Sbjct: 2155 TIPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            + +      DSG Y C A+N+AG         V       +PK   +     P I+  LK
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV-------QPK---RPEGTEPNIVSGLK 2264

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
               V EG+  E    + G P PT++WY+    +K S+  + +       L I+E + ED 
Sbjct: 2265 SVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRRVRSTLENGIARLVITETWAEDM 2324

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G YKC   N  GR + +A L +    + +    LT    + V EG  A+F+ ++     P
Sbjct: 2325 GTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLT---KVEVTEGDRAKFEVRVKGYPYP 2381

Query: 4751 TIQWLREGALIPETPDFQM--IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             ++W      I +   F++  + E     L +G   +ED G + C A   AG+    A L
Sbjct: 2382 EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441

Query: 4809 VVKSK 4813
             V  +
Sbjct: 2442 EVNER 2446



 Score =  139 bits (336), Expect = 6e-32
 Identities = 188/799 (23%), Positives = 316/799 (39%), Gaps = 75/799 (9%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF-NFGYVALTIKSVTVHDA 979
            +KEG  A F  ++   G     V+W    R +E   RI     + G  +L I  +   DA
Sbjct: 4528 LKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDA 4585

Query: 980  GHYTCRAYNAIGQATTSANLTIVTKKDII-AESQH--PGGLEKIQYLEDASRYSKRTEEE 1036
            G Y C A N  G  +  A L +  ++D + AE     P   E     +  +  SK ++ E
Sbjct: 4586 GVYKCVAENDDGSISCEAELIVDIEEDELDAEPTEVEPAPAEPTP-TKIQTEVSKPSKRE 4644

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096
                 KP F   L    ++ EG++   + ++ PQ +    V WY + K++   +RI    
Sbjct: 4645 PAPAPKPVFASELID-KQVKEGENLSLDVKL-PQ-EYKAEVAWYRDDKKLEDDHRITIIA 4701

Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRH 1156
                  L I  V  +D  VY VVA NA+G       + VE R  +   +  RG       
Sbjct: 4702 AGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVLVEERIKVPQIANIRGG------ 4755

Query: 1157 IEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHN 1216
                           +S+  P F++   +      G  I +E R    G   + + WF N
Sbjct: 4756 -------------SRLSQVAPEFMEQCKSTTVQENGTAI-MEVRAT--GSQPLSIRWFKN 4799

Query: 1217 GRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276
             +++  G R K   D     L I      D G Y     N  G+A   A++ V     +V
Sbjct: 4800 QQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTV---EPMV 4856

Query: 1277 TDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQP 1336
            +D ++            +  +T+  +   +    P     L N+E   G +V LE    P
Sbjct: 4857 SDGEDGAT-------HGSPPKTRGTKPKKSSGAKPSIVTPLANMEVFSGDDVMLEVISGP 4909

Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
              +Q  ++EWF + + I+   RF    E     L + +   +D G++ C   N  G  + 
Sbjct: 4910 --EQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFG--IA 4965

Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENV 1456
            SC+  ++ ++D   ES   S  +  +  +  +R ++    D    ++  F    K  E V
Sbjct: 4966 SCSAEILVEED--EESYSESSAD--EATDRNARIERRRSRDSICALE--FQQELKDRE-V 5018

Query: 1457 IEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR--FRPIHDFGYVALDIIDLIAEDS 1514
            ++G  +HF+ ++    +   KV W+K+ + +    R  F    + G  +L I     +D 
Sbjct: 5019 LDGDTIHFDVRITGRPEP--KVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDE 5076

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVT 1574
            G Y C A N  GT      L      +   +T ++           R +           
Sbjct: 5077 GDYRCVAANPAGTISCQAELLVEDVPEEEDTTDSKPAPATAPKPAKRKE----------- 5125

Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSR-FTETNNFG 1633
             +AP+ T  LK+  IK+G  A F+ R+I     T  V W   +K +   S    +  + G
Sbjct: 5126 -EAPVFTALLKDRTIKDGDAARFDARVI--GFPTPDVTWLREDKQITPNSHPHMKALHEG 5182

Query: 1634 FV-ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK--KSIYLESQHEGALPRLNQ 1690
             V +L I     +DSG Y C A N+ G+  T G   V     K I    + E     L +
Sbjct: 5183 EVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEGPEFKPIKGVQKPERKSSGLAR 5242

Query: 1691 LEDTSKYQRHSAQDEVITQ 1709
            +E+    + ++A  + +++
Sbjct: 5243 IEEVLTLKLYTATSDFLSE 5261



 Score =  137 bits (331), Expect = 2e-31
 Identities = 144/517 (27%), Positives = 209/517 (40%), Gaps = 69/517 (13%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            E +G +P F+V L N E + EG  A  E R+  +  P  +V WY + + L    +++   
Sbjct: 3973 EFEGISPRFSVKLKNQEVI-EGSTARLECRIVGSPVP--EVRWYRDNEPLIESEKYQMEQ 4029

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTID 3533
            D     L +     ED G Y   A N  G  V TA + V+               E  ID
Sbjct: 4030 DGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHPDT---------DEESDID 4080

Query: 3534 KIAA--LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV 3591
             + A  LE       T  P+      PE      D  + E  S  F CR    +     V
Sbjct: 4081 AVDARPLESKPSKPKTEIPK------PEIVLGLRDRFVVEGMSVRFNCRT--TSQPKPYV 4132

Query: 3592 EWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
             WF +G+PL +  R +  +  G   L I      DAG+Y C+ +N  G            
Sbjct: 4133 TWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGG------------ 4180

Query: 3652 RQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGG 3711
                          K+GT +   +EE    R  +       +PPRF  E+K  I V  G 
Sbjct: 4181 --------------KAGTSAHLTVEELPKSRPSVVA-----SPPRFQEELKGVITVV-GT 4220

Query: 3712 PVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND----FGFIALDIDYIYARDAGE 3767
                   +  +G PT  I+W+ + R    G R+    D    F  ++L I  +   D G 
Sbjct: 4221 TTKLSVPI--IGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGR 4278

Query: 3768 YTCRATNKWGSATTTAKITCSAKRDIVLESQLPQG-MSGEKIKELERGRISDAP--KEEP 3824
            Y C A NK G+  ++A +      D   E  + +G MS  K    E  R+ D P  +  P
Sbjct: 4279 YKCVAKNKSGTDFSSATVKVKELDD---EDSIQEGAMSLPKSTSDEALRMEDIPVAQSTP 4335

Query: 3825 IV-STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            +    PP+FI +++   ++E E  RF CRV  + DP    EW R  K +  G RY  + D
Sbjct: 4336 LKRGEPPEFIRKLRDQFIQEKETARFVCRVIGRPDPTY--EWLRGDKPITDGGRYTIMSD 4393

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
                +L+I     ED G Y C + N  G D T A ++
Sbjct: 4394 DEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLT 4430



 Score =  137 bits (331), Expect = 2e-31
 Identities = 182/760 (23%), Positives = 304/760 (40%), Gaps = 77/760 (10%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH-DFGYVA 1769
            PVF    +  R+ E   A F  ++   G P+  V+W      IE  +R+     D G  +
Sbjct: 4517 PVFVQKPETCRLKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECS 4574

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ-SKASLQLE-SQHESALQKIQQLEDS 1827
            L +  ++ ED+G Y C A N+ G     + L V   +  L  E ++ E A  +    +  
Sbjct: 4575 LVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTEVEPAPAEPTPTKIQ 4634

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887
            +   +    E A    P F ++L    ++ EG++   + ++    +    V WY + K L
Sbjct: 4635 TEVSKPSKREPAPAPKPVFASELIDK-QVKEGENLSLDVKLPQ--EYKAEVAWYRDDKKL 4691

Query: 1888 QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            +  HR           L I  V  +D   Y   A N  G       + V+ +  +     
Sbjct: 4692 EDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVLVEERIKV----- 4746

Query: 1948 HESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDP 2007
                  +I  +   SR  +           P+F +  K+  V E     +E   T     
Sbjct: 4747 -----PQIANIRGGSRLSQVA---------PEFMEQCKSTTVQENGTAIMEVRAT--GSQ 4790

Query: 2008 TMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067
             + + W+ N + ++ G R K + D  +  L I     +D G YMC  +N  G A   + +
Sbjct: 4791 PLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALL 4850

Query: 2068 KVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRA 2127
             V+          D +         K    KP  ++  G +P  +T L ++E +  GD  
Sbjct: 4851 TVEPM------VSDGEDGATHGSPPKTRGTKP--KKSSGAKPSIVTPLANME-VFSGD-- 4899

Query: 2128 HFECRVEPINDPHLT--IDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCK 2185
              +  +E I+ P     I+WF + + IR   R+  T +     L I     +D G + C 
Sbjct: 4900 --DVMLEVISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCV 4957

Query: 2186 ATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPK--ISPPR 2243
              N  G  + +C+ +       IL  +      +    EA   + RIE    +  I    
Sbjct: 4958 LLNDFG--IASCSAE-------ILVEEDEESYSESSADEATDRNARIERRRSRDSICALE 5008

Query: 2244 FVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR--FHITFDFGYVS 2301
            F  EL+    V +G T HF+ ++    +P  ++ +Y + K L  + R  F    + G  S
Sbjct: 5009 FQQELK-DREVLDGDTIHFDVRITGRPEP--KVVWYKDDKELVESKRIIFVSEPETGLYS 5065

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L I+    +D G+Y   A N  G        T++ +  ++ E    E  E   + + A P
Sbjct: 5066 LLIKKATLDDEGDYRCVAANPAG--------TISCQAELLVEDVPEE--EDTTDSKPA-P 5114

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
               P+ P     + PVFT  L++   I++G  A FD R+I  G PT  V W R +K I  
Sbjct: 5115 ATAPK-PAKRKEEAPVFTALLKD-RTIKDGDAARFDARVI--GFPTPDVTWLREDKQITP 5170

Query: 2422 SS--RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +S   +   H+    S+ I+    +D GVY C A N  G+
Sbjct: 5171 NSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQ 5210



 Score =  136 bits (330), Expect = 3e-31
 Identities = 126/505 (24%), Positives = 206/505 (40%), Gaps = 48/505 (9%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS-LLIKQIGPGDEGE 143
            +G +      + G P+P VSW +    +++  K   R   + GD S L++      D G 
Sbjct: 1877 EGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQETR---KRGDESHLVVFNAKMEDAGS 1933

Query: 144  YTCTARNQYGEAICSVYIQ-----PEGXXXXXXXXXXXXXYRHVSETVEHKAYGT-QGYT 197
            Y C A N+ G    +  ++     PEG                V E  E K Y    GY 
Sbjct: 1934 YKCEANNKLGTVTKTYNVKVMSTAPEGQAPSFTSEMSQV---EVDEGGEVKLYFLISGYP 1990

Query: 198  TEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEID 257
                + T+           S D  +V      +     + E + K  +       +T + 
Sbjct: 1991 KPTVKWTRDGIPVFEDYRISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQ 2050

Query: 258  RSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
              +   S  P   QK +N + + G D +F++Q+ G P P VT+ +  +++ +  ++ I+ 
Sbjct: 2051 VIVTQRSIRPIFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVE 2110

Query: 317  THNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQ 375
              N    L +RNT+  D+G Y         CI  +G  A E  ++ Y             
Sbjct: 2111 EENGLFVLTIRNTRPEDAGEYQ--------CIAVNG--AGEVTSKGY------------- 2147

Query: 376  QRETEERIEISEKALAPQFV-KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
                   + + E+   PQF+  V    ++ +G        V G P PE+ W+ N+R I  
Sbjct: 2148 -------LHVEEELTIPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYA 2200

Query: 435  DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE-QVVAPKF 493
                ++    S    + + NVTL DSG+  C A N +G  + Q  +NV  K  +   P  
Sbjct: 2201 TSRVQLSFISS-KATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNI 2259

Query: 494  VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
            V    ++ V+EGE   L     GTPTP + W +DG+ +  +  +R   + G + L I   
Sbjct: 2260 VSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRRVRSTLENGIARLVITET 2319

Query: 554  KASDAAWYQCTAQNVAGSTATRARL 578
             A D   Y+C  +N  G T+T A L
Sbjct: 2320 WAEDMGTYKCQVRNDLGRTSTSAHL 2344



 Score =  133 bits (321), Expect = 4e-30
 Identities = 172/728 (23%), Positives = 282/728 (38%), Gaps = 78/728 (10%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY----DGMYH 4166
            P F +    V   EGE  +   +V G+PKP + W      IV   R+K+      DG+Y 
Sbjct: 686  PEFRTKLKPVKAVEGEEVQLDVKVEGYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGLYS 745

Query: 4167 FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQR 4226
              I K +  DTG I+V+             L+V  R        + AP    DE      
Sbjct: 746  LVISKLQLDDTGTIKVVATNASGKATSRADLEVKER--------EFAPEFEGDEEGPIVV 797

Query: 4227 TETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN-KLQELE 4285
            TE   E + + R        +D   + +P  I E     ++ +KR+  E      +  LE
Sbjct: 798  TEGN-EVSIQLRVKANPNADVDWFKDGRP--IYEST---KRDIKRRGEEHTLAIHVSSLE 851

Query: 4286 NEQVIK---ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVT 4342
            +  V K    +RL +++  + +          A  +  +      +TEE  E +++   T
Sbjct: 852  DTGVYKCEASNRLGKASRSFDVKVQVKGPKGEAPIILSKLRPV--ETEEGEETKLKCTFT 909

Query: 4343 QKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGD------KEITRKITSTETTEIEHK--- 4393
             KP      E T  G  + +   +  Q +   D      KE T          I++    
Sbjct: 910  GKPA--PTCEWTRDG--IRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGT 965

Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
              T   V+   V+    P+  +K++   V   E+A F +   G     + W+++   + +
Sbjct: 966  VSTSAEVLVNEVEKGVGPVIEEKLKDVTVMPGEEAEFSIRVSGRAE--VDWFKDEVMLND 1023

Query: 4454 SPDFQIHTFST-KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK----RRQGR 4508
               F +      +  L I  V  ED   +  +  N  G     A L ++E          
Sbjct: 1024 EGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIKEAIVAPEEVDA 1083

Query: 4509 GGIVP-----PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
               VP     P  T   ++V V  G+   L+  V+G+    V W K+  K++   R K  
Sbjct: 1084 AETVPIEGSAPKITKPLESVEVNEGEDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEK 1143

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623
             +     L+  +A P+D G+Y+C  IN  G+A    E  V++ +     +P+ K   +P 
Sbjct: 1144 LDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLS-----RPEFKIKMSPV 1198

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
            E         V EG    F  ++ G P   V+W+KG   I+ S  +  +   + YT+ I+
Sbjct: 1199 E---------VTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIA 1249

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                ED G Y+CVA N+AG+ T  A L V + + A          D  V   +  + K  
Sbjct: 1250 NVTLEDAGGYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTIDSEV--NKEVEIKVT 1307

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                I+ +I             D + I  G++    I      D G + C+AT AAG   
Sbjct: 1308 TGEPIRDSI-----------NTDVRAI--GDSHTCFIVRAKLSDAGVYKCQATNAAGSAS 1354

Query: 4804 TSAKLVVK 4811
             S ++ VK
Sbjct: 1355 RSWEVKVK 1362



 Score =  132 bits (318), Expect = 9e-30
 Identities = 97/358 (27%), Positives = 153/358 (42%), Gaps = 34/358 (9%)

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQG--RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
            FAA  E R  T +  ++   +E++ +G  +    PP FTL  +N  V  G + +  ++V 
Sbjct: 3841 FAARKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVI 3900

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
               PI V W K+ + +  D      E D   Y + I      D G Y  V  N  G    
Sbjct: 3901 SKAPIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVES 3960

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             A   V        P+ + +     P     LK++ V EG      C+IVG P+P V+WY
Sbjct: 3961 KAYLNVL-------PEMEPEFEGISPRFSVKLKNQEVIEGSTARLECRIVGSPVPEVRWY 4013

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD- 4716
            + ++ +  S+ +QM +  D + L + +   ED+G YK VA N AGR    A + V  PD 
Sbjct: 4014 RDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHPDT 4073

Query: 4717 --QAD------------------NLP---ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
              ++D                   +P    +  LRD  V EG   +F  + TS+ KP + 
Sbjct: 4074 DEESDIDAVDARPLESKPSKPKTEIPKPEIVLGLRDRFVVEGMSVRFNCRTTSQPKPYVT 4133

Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            W ++G  +     +++        L I +    D G + C  +   G+  TSA L V+
Sbjct: 4134 WFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVE 4191



 Score =  131 bits (317), Expect = 1e-29
 Identities = 122/518 (23%), Positives = 202/518 (38%), Gaps = 42/518 (8%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            E   P F          +GG  K    + G P P V WTR   P+ E  + SM  +   G
Sbjct: 1959 EGQAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRVQG 2018

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVY-IQPEGXXXXXXXXXXXXXYRHVSETV 186
             V+L+I+ +   DEG Y CT +NQ+G    +V  I  +                 + E V
Sbjct: 2019 -VTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRSIRPIFGQKMKNVEGRIGEDV 2077

Query: 187  --EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLR--EVSFRESITK 242
              E +  GT        R+++++ Y  G      ++  +     R  R  +    + I  
Sbjct: 2078 RFEIQVEGTPVPAVTFHRESEQI-YDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAV 2136

Query: 243  RYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN 302
               GE   +    ++  L    P  I   P   +L +G +    +++ G PRP + W+ N
Sbjct: 2137 NGAGEVTSKGYLHVEEEL--TIPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHN 2194

Query: 303  GQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
             + +  +++ ++    +  T+ + N    DSG Y   A N  G             T S 
Sbjct: 2195 ERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG-------------TGS- 2240

Query: 363  VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
                  Q+  + Q +  E           P  V   +  +V EG+    +  V+G P P 
Sbjct: 2241 -----KQFNINVQPKRPE--------GTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPT 2287

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            + W+ +  ++++    +  + E+G   L+IT     D G   C  RN  G T+    LN+
Sbjct: 2288 LEWYRDGLRVKESRRVRSTL-ENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT- 541
            I       P+F E+ + + V EG+      R  G P P + W      I+      I + 
Sbjct: 2347 I---VATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEIESV 2403

Query: 542  -DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             + G  +L +      DA  Y+C A N AG +  RA L
Sbjct: 2404 KETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441



 Score =  130 bits (313), Expect = 4e-29
 Identities = 103/417 (24%), Positives = 173/417 (41%), Gaps = 21/417 (5%)

Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ 4458
            R+ EG ++PS   I   + +P   +E           G PLP +++ ++  P+  S   +
Sbjct: 2736 RLAEGMIEPSFIGI---EFEPITAYEGSDIDLTFYVKGRPLPTVEFLKDEVPVFKSDRTE 2792

Query: 4459 IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL 4518
            + +   +  L +  + V DSA + AVA+N+ G A+ S  L+V+ KR   + G   P    
Sbjct: 2793 LTSNGNRHTLYLSDLAVRDSATYKAVAKNKAGVARRSVELLVKPKRGL-KPGEAAPEIVQ 2851

Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP 4578
              +   V  G   +L  +VTGT    + W K+   ++P+ R  I      Y L  LE   
Sbjct: 2852 RLKACEVPEGSSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEA 2911

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
            +D G+Y  VA N  G     AE ++  P+             +PP     L    V EG 
Sbjct: 2912 RDEGRYMLVAKNHLGSVSTSAELIIE-PSV------------SPPSFRHRLTAVEVDEGD 2958

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCV 4696
               F  ++  +P  +V+WYK  + I    +F++    +E  Y+L IS     D G YKC 
Sbjct: 2959 ETRFDVRLKKEP-TSVEWYKEQQRIFTDGHFEVIEGEEECLYSLVISNTKVADAGGYKCT 3017

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
            A N +G+ +  A+L V +                 + EG        +     P I+W +
Sbjct: 3018 ALNESGKSSTRAELLVNERLIPPGFEG-PDHGSYELQEGDTITLDAVVKGNPYPEIRWYK 3076

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +  L  E+    +        L + +   +D+G + C      G    S  + V++K
Sbjct: 3077 DEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAK 3133



 Score =  130 bits (313), Expect = 4e-29
 Identities = 191/800 (23%), Positives = 307/800 (38%), Gaps = 83/800 (10%)

Query: 734  IERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQ 793
            +E  +  PET     Q  D       ES E    Q+P+  R       L+EG  A F  +
Sbjct: 4490 VEEEALLPETASRADQTPDEPT---AESGEPVFVQKPETCR-------LKEGDTARFNVK 4539

Query: 794  LTPVSDPTMRVEWYKDGRPITASSRIT-SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852
            +    +P   V+W+   R I    RI     + G  SL IM +  EDAG Y   A N  G
Sbjct: 4540 VNGSPEPF--VDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDG 4597

Query: 853  EAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFK 912
                 A + V              +    E T                  P    KP F 
Sbjct: 4598 SISCEAELIVDIEEDELDAEPTEVEPAPAEPTPTKIQTEVSKPSKRE---PAPAPKPVFA 4654

Query: 913  TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIK 972
            + + D+  +KEG     + +L    +    V W +D + +E   RIT         LTI 
Sbjct: 4655 SELIDK-QVKEGENLSLDVKLPQ--EYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIF 4711

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKR 1032
             V++ D   Y   A NA G  TTS +  ++ ++ I         + +I  +   SR S+ 
Sbjct: 4712 GVSIKDEAVYKVVATNASG--TTSCDCEVLVEERI--------KVPQIANIRGGSRLSQ- 4760

Query: 1033 TEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRI 1092
                      P F+   K T  + E  +A  E R      L  ++ W+ N + I    RI
Sbjct: 4761 --------VAPEFMEQCKSTT-VQENGTAIMEVRATGSQPL--SIRWFKNQQTIKYGGRI 4809

Query: 1093 QTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYE 1152
            +   D  +  L I+ V  +D G+Y  V  N AG A   A +TVE   S        G   
Sbjct: 4810 KMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPP 4869

Query: 1153 KTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVE 1212
            KTR  +  K           S +KP  V PL+N   V  G ++ LE    P  +   ++E
Sbjct: 4870 KTRGTKPKK----------SSGAKPSIVTPLAN-MEVFSGDDVMLEVISGP--EQVKKIE 4916

Query: 1213 WFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            WF +   +    RF    +     L I  AT  D G +    +N  G A  SA + V E 
Sbjct: 4917 WFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEED 4976

Query: 1273 SDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLEC 1332
             +  +++  ++A ++   +E   RR+   R+ I  +   +F + L + E ++G  +H + 
Sbjct: 4977 EESYSESSADEATDRNARIE--RRRS---RDSICAL---EFQQELKDREVLDGDTIHFDV 5028

Query: 1333 RLQPVGDQTMRVEWFCNGKPIKTGHR--FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQ 1390
            R+   G    +V W+ + K +    R  F    E    +L +     +D G Y C A N 
Sbjct: 5029 RI--TGRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANP 5086

Query: 1391 LGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRP 1450
             G    SC   ++ +   + E +  +  +           +K +    +  +K R     
Sbjct: 5087 AG--TISCQAELLVED--VPEEEDTTDSKPAPATAPKPAKRKEEAPVFTALLKDR----- 5137

Query: 1451 KSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH--RFRPIHDFGYVALDIID 1508
                 + +G    F+ ++  +      V W +  + +T       + +H+    +L I +
Sbjct: 5138 ----TIKDGDAARFDARV--IGFPTPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITE 5191

Query: 1509 LIAEDSGIYTCRAVNLVGTD 1528
               +DSG+Y C A N  G D
Sbjct: 5192 GGYKDSGVYKCIAKNSAGQD 5211



 Score =  129 bits (311), Expect = 6e-29
 Identities = 196/821 (23%), Positives = 326/821 (39%), Gaps = 105/821 (12%)

Query: 3161 LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS-DFGFVVLDIAYTQNHDS 3219
            LK+G +A F   V     P+  ++W+   + +    RI+    D G   L I      D+
Sbjct: 4528 LKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDA 4585

Query: 3220 GEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP----- 3274
            G Y C A N  G      +I+C  +  V +E  + D  A+  E+E        T      
Sbjct: 4586 GVYKCVAENDDG------SISCEAELIVDIEEDELD--AEPTEVEPAPAEPTPTKIQTEV 4637

Query: 3275 STPSA-EP-----PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHG 3328
            S PS  EP     P F +++ D  ++ EG++   + +L    +   +V W+ + KKL   
Sbjct: 4638 SKPSKREPAPAPKPVFASELID-KQVKEGENLSLDVKLP--QEYKAEVAWYRDDKKLEDD 4694

Query: 3329 HRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPR 3388
            HR        +  L I     ++   Y+ VATN  G  S    +     E  I   Q+  
Sbjct: 4695 HRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVLV---EERIKVPQIAN 4751

Query: 3389 GMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTD 3448
             + GG    Q   + M + K T+V+E                       A  E R T + 
Sbjct: 4752 -IRGGSRLSQVAPEFMEQCKSTTVQENG--------------------TAIMEVRATGSQ 4790

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
               L + W+ N +++K G R +   D     L+ISP   +D G Y+C   N  G A   A
Sbjct: 4791 P--LSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEA 4848

Query: 3509 SMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLI 3568
             + V        E  +  G +G      A  G         P+  SG  P   T  +++ 
Sbjct: 4849 LLTV--------EPMVSDGEDG------ATHGSPPKTRGTKPKKSSGAKPSIVTPLANME 4894

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAG 3628
            +        E  +I   +   ++EWF + + +    R    ++     L I      D G
Sbjct: 4895 VFSGDDVMLE--VISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEG 4952

Query: 3629 LYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE 3688
            ++ C   N  G A+ S ++ V+  +    E    S     T+   ++E    +     +E
Sbjct: 4953 IFKCVLLNDFGIASCSAEILVEEDE----ESYSESSADEATDRNARIERRRSRDSICALE 5008

Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748
                    F  E+KD  +V +G  +HFD R+   G P  ++ W+ + +      R+  ++
Sbjct: 5009 --------FQQELKDR-EVLDGDTIHFDVRI--TGRPEPKVVWYKDDKELVESKRIIFVS 5057

Query: 3749 --DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
              + G  +L I      D G+Y C A N  G+      I+C A+   +L   +P+    E
Sbjct: 5058 EPETGLYSLLIKKATLDDEGDYRCVAANPAGT------ISCQAE---LLVEDVPE----E 5104

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWY 3866
            +     +   + APK        P F   +K  T+++ +  RF+ RV     P   + W 
Sbjct: 5105 EDTTDSKPAPATAPKPAKRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPD--VTWL 5162

Query: 3867 RNGK-LLPSGHRYRTVYDMGFV-SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL 3924
            R  K + P+ H +      G V SL I     +DSG Y C A N  G+D T   +  +  
Sbjct: 5163 REDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEG- 5221

Query: 3925 PDIILQNQVPRGMKRSEALTQME--ATIKKYT-SEVYLTED 3962
            P+      V +  ++S  L ++E   T+K YT +  +L+E+
Sbjct: 5222 PEFKPIKGVQKPERKSSGLARIEEVLTLKLYTATSDFLSEE 5262



 Score =  128 bits (310), Expect = 8e-29
 Identities = 95/339 (28%), Positives = 154/339 (45%), Gaps = 29/339 (8%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I     N ++  G D   +V        ++ WFK+ + + +  +  + +     TL +
Sbjct: 4884 PSIVTPLANMEVFSGDDVMLEVISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTI 4943

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
                  D G +  +  N  G    S  + VE   ESY +    +  TD   R    R   
Sbjct: 4944 ATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADE-ATDRNARIERRRSRD 5002

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE- 444
            S  AL  +F +  +DR+V +G    FD R+TGRP P+V W+ +D+++ +     I V+E 
Sbjct: 5003 SICAL--EFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVES-KRIIFVSEP 5059

Query: 445  -SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL---NVIEKEQ--------VVAPK 492
             +G ++L+I   TL D G   CVA N +G  + Q  L   +V E+E           APK
Sbjct: 5060 ETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEEDTTDSKPAPATAPK 5119

Query: 493  FVER------FSTL----NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN--PELRIH 540
              +R      F+ L     +++G+    +AR +G PTP +TW ++   I PN  P ++  
Sbjct: 5120 PAKRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKAL 5179

Query: 541  TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             +G   +L I      D+  Y+C A+N AG   T   L+
Sbjct: 5180 HEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLF 5218



 Score =  125 bits (302), Expect = 8e-28
 Identities = 225/953 (23%), Positives = 367/953 (38%), Gaps = 151/953 (15%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  + L  Q++ +  P   +EWFK          +K   +     L I     +DSG Y
Sbjct: 3640 EGAPIKLIVQIKGKPAPT--VEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNY 3697

Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXV 2775
             C+ATN  G    T  + + ++  ++     P      GA+                   
Sbjct: 3698 RCQATNDAGTVTKTFKVVVNEQKVVMRRQPIPP-----GAVKPS---------------- 3736

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLD 2834
            F+  + ++   EG        V+   +P  +I+W+ +N+ +  G R +    +     L 
Sbjct: 3737 FLQRMQDLEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEEDGLCMLV 3794

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL--RCTG-DKNIY-FDTQHPQGKAGLEA-VEQ 2889
            I    + D G Y C  +N+ G A  S  L     G D  +   D      K   E+ +E 
Sbjct: 3795 IRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIEL 3854

Query: 2890 AEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949
              +    + +    P  E   PE+ + +    ++ EG V     +V  K    +K+EWY 
Sbjct: 3855 ISDDTSDEEKTEGAPKEEGAPPEFTL-VLRNREVKEGGVTKFASRVISK--APIKVEWYK 3911

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL 3009
            + +++        +SD+   T      +E D  +Y     N +       T   ++K   
Sbjct: 3912 DDRLI--------SSDWPRHT------FEHDEDLYAMNISNVKVADGGPYTFVVSNKYGT 3957

Query: 3010 IERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYE 3069
            +E   +                L   P  +P+ + G  P F+   K+  ++ EG  A  E
Sbjct: 3958 VESKAY----------------LNVLPEMEPEFE-GISPRFSVKLKN-QEVIEGSTARLE 3999

Query: 3070 ASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKW 3129
              ++  G     + W+ + + +  S + +         L +      D G Y   A N  
Sbjct: 4000 CRIV--GSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVARNIA 4057

Query: 3130 GQ----AEISVK---------LECVD----KSKGQKPRFTTHIQNIE---GLKD-----G 3164
            G+    A+ISVK         ++ VD    +SK  KP+  T I   E   GL+D     G
Sbjct: 4058 GRDVCTADISVKHPDTDEESDIDAVDARPLESKPSKPK--TEIPKPEIVLGLRDRFVVEG 4115

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
             S  F C       P   + W+ +GQP+    R +  S  G   L I   +  D+G Y C
Sbjct: 4116 MSVRFNCRTT--SQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKC 4173

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
               N  G+  T A              L  + L K R            PS   A PP+F
Sbjct: 4174 EVSNVGGKAGTSA-------------HLTVEELPKSR------------PSVV-ASPPRF 4207

Query: 3285 ITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD----FGIV 3340
              +++ V  +V G +      ++    P   +EW+ + +++  G R R   D    F IV
Sbjct: 4208 QEELKGVITVV-GTTTKLSVPII--GHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIV 4264

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400
             L I      + G Y+CVA NK G D + A +K   KE   LD +     EG +   ++ 
Sbjct: 4265 SLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKV--KE---LDDE-DSIQEGAMSLPKST 4318

Query: 3401 EDSMVRRKDTSVEE----EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456
             D  +R +D  V +    ++G+ P F   L + + ++E E A F  R+    DP    EW
Sbjct: 4319 SDEALRMEDIPVAQSTPLKRGEPPEFIRKLRD-QFIQEKETARFVCRVIGRPDPTY--EW 4375

Query: 3457 YWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
                K +  G R+    D     LEI+    ED G Y C + N+ G   TTA + V+  R
Sbjct: 4376 LRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASR 4435

Query: 3517 NIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESG---NPPEFTTTPSD 3566
                   + K +E  + K A+++  S +       AES      PE  + P+D
Sbjct: 4436 R-----PISKNIEKLLIKAASMDEESMSQALAKAIAESPELLGEPEPESKPAD 4483



 Score =  123 bits (297), Expect = 3e-27
 Identities = 121/510 (23%), Positives = 214/510 (41%), Gaps = 48/510 (9%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G     + +++ NP   V W +   P+ E  K  ++   +   +++ +  +   D G Y
Sbjct: 799  EGNEVSIQLRVKANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLE--DTGVY 856

Query: 145  TCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY----GTQGYTT 198
             C A N+ G+A  S  V +Q +G                  E  E K      G    T 
Sbjct: 857  KCEASNRLGKASRSFDVKVQVKGPKGEAPIILSKLRPVETEEGEETKLKCTFTGKPAPTC 916

Query: 199  EQSR-----QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIS 253
            E +R     ++ ++   + T+ SST   K  T +   L + + +  +    V  S   + 
Sbjct: 917  EWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGT--VSTSAEVLV 974

Query: 254  TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE 313
             E+++ +GPV    I +K ++  +  G +A+F +++SG  R  V WFK+ + ++N     
Sbjct: 975  NEVEKGVGPV----IEEKLKDVTVMPGEEAEFSIRVSG--RAEVDWFKD-EVMLNDEGRF 1027

Query: 314  IIT--THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYI 371
            I+    +   +L + + +  D G Y  L  N +G + T   L ++            + I
Sbjct: 1028 IMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIK------------EAI 1075

Query: 372  TDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ 431
               ++ +  E + I  +  AP+  K  +  +V EG+    +C V+G P P V W  +  +
Sbjct: 1076 VAPEEVDAAETVPI--EGSAPKITKPLESVEVNEGEDFDLECVVSGSPSPTVEWTKDLVK 1133

Query: 432  IRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGE--TAFQCRLNVIEKEQV 488
            +R  Y  K  ++  GN A L+       D G   C   N+ G+  T  + ++NV+ +   
Sbjct: 1134 LRTSYRLKEKLD--GNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSR--- 1188

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
              P+F  + S + V EG       R  G P  ++ W K    I  +       D    T+
Sbjct: 1189 --PEFKIKMSPVEVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYTFTADKNRYTM 1246

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I      DA  Y+C A N AG T +RA L
Sbjct: 1247 VIANVTLEDAGGYRCVATNTAGKTTSRADL 1276



 Score =  123 bits (296), Expect = 4e-27
 Identities = 134/511 (26%), Positives = 210/511 (41%), Gaps = 58/511 (11%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT-T 960
            +P    KP F   ++D + I EG  A    R++ + +    ++W KD R +    R+   
Sbjct: 3728 IPPGAVKPSFLQRMQD-LEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFE 3784

Query: 961  FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI--------VTKKDIIAESQ 1012
            F   G   L I+  T  D G Y C   NA G+A  SA L I        V+  D+   ++
Sbjct: 3785 FEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAAR 3844

Query: 1013 HPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSD 1072
                   I+ + D +   ++TE   K    P     +    ++ EG    F +RV   S 
Sbjct: 3845 KEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRV--ISK 3902

Query: 1073 LTMTVEWYFNGKQITSANRIQTY-HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSA 1131
              + VEWY + + I+S     T+ HD    A++I++V+  D G YT V  N  G      
Sbjct: 3903 APIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYG------ 3956

Query: 1132 SMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
              TVE+++ ++       L E          +EP  + E IS   P F   L N   V E
Sbjct: 3957 --TVESKAYLNV------LPE----------MEP--EFEGIS---PRFSVKLKN-QEVIE 3992

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G    LECR+  +G P   V W+ +   +    +++   D    AL +   +  D G Y 
Sbjct: 3993 GSTARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYK 4050

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP 1311
              A N  G    +A + V        DT  E  I+ +    DA     +  +  T +  P
Sbjct: 4051 AVARNIAGRDVCTADISVKH-----PDTDEESDIDAV----DARPLESKPSKPKTEIPKP 4101

Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371
            +    L +   VEG +V   CR          V WF +G+P+ +  R+         +L 
Sbjct: 4102 EIVLGLRDRFVVEGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSLT 4159

Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +      D+G+Y C+ +N  G+A TS  L V
Sbjct: 4160 IKDCKLADAGIYKCEVSNVGGKAGTSAHLTV 4190



 Score =  121 bits (292), Expect = 1e-26
 Identities = 105/418 (25%), Positives = 177/418 (42%), Gaps = 28/418 (6%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            VE P    + P   +++QP    E E  + E    G+P P I W ++          + +
Sbjct: 2541 VEVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTY 2600

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                   L IR V + D  ++   A+N  G+A  SA L V E  R+ R     P      
Sbjct: 2601 FDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLE--REAR-----PRILEKL 2653

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP-Q 4579
            Q+V+ + G+      +V+G+    V W +  +++       + +E   Y  L +E    +
Sbjct: 2654 QDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLTIEYIDYE 2713

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D G Y+ V IN +GE    A     L   +   +P            EP+      EG  
Sbjct: 2714 DEGAYKAVVINDSGEVSSTA----VLRLAEGMIEPSFIGIE-----FEPI---TAYEGSD 2761

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            I+ +  + G+PLPTV++ K +  +  S   +++   + +TL +S+    D   YK VA N
Sbjct: 2762 IDLTFYVKGRPLPTVEFLKDEVPVFKSDRTELTSNGNRHTLYLSDLAVRDSATYKAVAKN 2821

Query: 4700 SAGRVTVAAKLKVTQP---DQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
             AG    + +L V         +  P +   L+   V EG   + + ++T    PTI+W 
Sbjct: 2822 KAGVARRSVELLVKPKRGLKPGEAAPEIVQRLKACEVPEGSSFKLRCRVTGTPTPTIEWY 2881

Query: 4756 REGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            +    +P  P+ ++I  H G+   L    T   D G +   A    G V TSA+L+++
Sbjct: 2882 KSN--MPLKPNGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIE 2937



 Score =  120 bits (290), Expect = 2e-26
 Identities = 108/488 (22%), Positives = 204/488 (41%), Gaps = 42/488 (8%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P ++W +    L +  K  +R + +   V++L  +  P D   Y C A N+ G+A 
Sbjct: 227 GKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAK--PEDTALYKCEAENKLGKAS 284

Query: 157 CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHS 216
            +  ++ +              +    E  E K           + +  K      T   
Sbjct: 285 RAFDVKVKAPKGDAPSFTIDLTHVRAIEGEESKLVCKVTGKPAPTIEWLKGELPVTTSLR 344

Query: 217 STDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEID--RSLGPVSPPKIAQKPRN 274
              DF+ +     ++++    ++ T + V  +D   +  I   +     + P+I    R+
Sbjct: 345 VRTDFEKNVATL-VIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTKPEIEDSLRD 403

Query: 275 SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT--TLRVRNTQKSD 332
                G   +F+V++ G P+P+V W K G+ +I   +   I   +    +L +++ +++D
Sbjct: 404 VSALPGERVKFKVRIGGKPKPKVEWRK-GKSVIEDGERFTIAEESDEVFSLIIQDLEETD 462

Query: 333 SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
           +G Y         C+ T+                      +  + E+  ++ ++E+ + P
Sbjct: 463 AGRYK--------CVATN----------------------EAGEAESMAQLTVNEELIGP 492

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM- 451
           +F K+ +   V EG+      RVTG+P PE+ W  + + +R   N  +   E  + A++ 
Sbjct: 493 RFEKMKESFTVVEGESVELVARVTGKPAPEIEWTKDGKTVRKTNN--VDTKERDDQAVLT 550

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE-QVVAPKFVERFSTLNVREGEPVVL 510
           I   +  DSG+  C ARNKSG      +L+V  K+ +  AP+ V     +   EG+  VL
Sbjct: 551 IEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAVL 610

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           +    G P P I W K+G+ +  +   +     G   L I   +A D   Y C  +N  G
Sbjct: 611 SCTISGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELG 670

Query: 571 STATRARL 578
           S  ++ +L
Sbjct: 671 SAESKTKL 678



 Score =  120 bits (289), Expect = 3e-26
 Identities = 119/523 (22%), Positives = 205/523 (39%), Gaps = 48/523 (9%)

Query: 65   RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
            +PGE +P I +++ K     +G + K   ++ G PTP + W +   PL    +  + +  
Sbjct: 2841 KPGEAAPEIVQRL-KACEVPEGSSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGH-- 2897

Query: 125  QTGDVSLL-IKQIGPGDEGEYTCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRH 181
             TGD   L   +    DEG Y   A+N  G    S  + I+P                  
Sbjct: 2898 -TGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVSPPSFRHRLTAVEVDE 2956

Query: 182  VSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
              ET        +  + E  ++ Q++ +T+G  H    + + +     ++      ++  
Sbjct: 2957 GDETRFDVRLKKEPTSVEWYKEQQRI-FTDG--HFEVIEGEEECLYSLVISNTKVADAGG 3013

Query: 242  KRYVGESDV-QISTEIDRSLGP-VSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVT 298
             +    ++  + ST  +  +   + PP        S +LQEG        + GNP P + 
Sbjct: 3014 YKCTALNESGKSSTRAELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVKGNPYPEIR 3073

Query: 299  WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            W+K+    + S K  +       +L + +    DSG Y  + +N  G           + 
Sbjct: 3074 WYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVG-----------TA 3122

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
            T+S+  D  ++                  K + P+F +  +  +  +G   RF+C+V+G 
Sbjct: 3123 TKSFTVDVEAK----------------KSKGIIPEFFRQLRRVEAVQGSTARFECKVSGH 3166

Query: 419  PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
            P P++ W  + +++      K    +     L        D G  TCVA N++GE +   
Sbjct: 3167 PEPQIAWLKDGKELAIPRYIKPFY-DGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHA 3225

Query: 479  RLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
             L V+ K  +V P+F ER   + V EG+    + R  G P P++ W K G  I      R
Sbjct: 3226 SL-VLSKP-LVMPEFKERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKKI--KSHAR 3281

Query: 539  IHTDGGAS---TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +  G     TL I      D   Y+C A N AG      RL
Sbjct: 3282 FSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRL 3324



 Score =  120 bits (288), Expect = 4e-26
 Identities = 115/511 (22%), Positives = 208/511 (40%), Gaps = 43/511 (8%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            S PIF+Q  K     +G + +FE KL   P P V W +  + + +  ++++   E +G  
Sbjct: 1468 SRPIFQQKLKAVSTIEGESTRFEVKLSAMPRPTVEWFKSSSQIYDGGRFTITEEENSGVY 1527

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE----T 185
             L+I+     D G Y   A N  G+      ++                    +E     
Sbjct: 1528 VLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEKTEGDDLE 1587

Query: 186  VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
            +  +  G      E  +  + +  ++  +  S D+    T     L +    + + +   
Sbjct: 1588 LTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKA 1647

Query: 246  GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
            G S    + ++ +     + P I     + +++EG     +  +SG P P + W+K+G R
Sbjct: 1648 GSSSRTFNLDVQKKKVIGNAPDIITHLISKEVKEGGTVTLECTVSGKPAPNIEWYKDGLR 1707

Query: 306  LINSNKHEIITTHNHTTLRVRNT--QKSDSGHYTLLAENPNGCIVTSGYLAVESPTE-SY 362
               + +  ++TT + +   V  T  Q  D G Y  +A NP G   +S  L V  P++  +
Sbjct: 1708 FTATRR--VMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSKPEF 1765

Query: 363  VQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
             Q  R   + +  + + + RI+   K     +    +  D    ++T         PY  
Sbjct: 1766 KQKLRPLEVVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQIT--------EPYE- 1816

Query: 423  VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
                       DD    I++N +   A M             CVA N++G+T  +  L V
Sbjct: 1817 ----------GDDTYSLIILNTTMEDAAM-----------YKCVAFNEAGKTTCRADLTV 1855

Query: 483  IEKEQVVAPKFV--ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH 540
            IEK+Q   P F+  +   T+ V+EG+ + ++A   G P+P ++W KDG  ++ + +    
Sbjct: 1856 IEKQQ--PPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQETR 1913

Query: 541  TDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              G  S L +  AK  DA  Y+C A N  G+
Sbjct: 1914 KRGDESHLVVFNAKMEDAGSYKCEANNKLGT 1944



 Score =  120 bits (288), Expect = 4e-26
 Identities = 175/788 (22%), Positives = 305/788 (38%), Gaps = 76/788 (9%)

Query: 1959 EDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGR 2018
            E  SR  +   + +    +P F +  +   + EG        +    +P   V+W+   R
Sbjct: 4498 ETASRADQTPDEPTAESGEPVFVQKPETCRLKEGDTARFNVKVNGSPEPF--VDWFLGRR 4555

Query: 2019 PVQQGHRFKTTY-DFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYL 2077
             +++  R +    D G  +L I+    ED G Y C A N  G     + + VD +    L
Sbjct: 4556 MIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEED-EL 4614

Query: 2078 DT----LDEQRLKKIQELEKYERPKPIEEEQ-PGQRPVFLTALTSLENLKEGDRAHFECR 2132
            D     ++    +      + E  KP + E  P  +PVF + L   + +KEG+    + +
Sbjct: 4615 DAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELID-KQVKEGENLSLDVK 4673

Query: 2133 VEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE 2192
            +    +    + W+ + +K+   HR           L I     +D   Y   ATN  G 
Sbjct: 4674 LP--QEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASG- 4730

Query: 2193 AVNTCTLKVAGHRNIILDTQHPNGLEKIRQL-EAQGHSTRIEVEEPKISPPRFVTELRGT 2251
               +C  +V     I           K+ Q+   +G S   +V       P F+ + + T
Sbjct: 4731 -TTSCDCEVLVEERI-----------KVPQIANIRGGSRLSQVA------PEFMEQCKST 4772

Query: 2252 THVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPED 2311
            T V E  TA  E  V       L I ++ N + ++   R  ++ D  + +L I     +D
Sbjct: 4773 T-VQENGTAIME--VRATGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKD 4829

Query: 2312 AGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPV 2371
             G Y     N  G       +TV     ++S+ +  +G         + P  R   P+  
Sbjct: 4830 EGLYMCVISNKAGTADCEALLTVEP---MVSDGE--DGAT-----HGSPPKTRGTKPKKS 4879

Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431
            +  +P    PL N++ +  G     +  +I   +   K+EWF++ +LI D  R T T + 
Sbjct: 4880 SGAKPSIVTPLANME-VFSGDDVMLE--VISGPEQVKKIEWFKDNELIRDRPRFTVTSED 4936

Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLE 2491
               ++TI+    +DEG++ C   N  G                  E+   E   +  ++E
Sbjct: 4937 TRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIE 4996

Query: 2492 QPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVEL 2551
            +   RRS +     E   F Q L    E+ +G   H++ R+   G P  +  WY +  EL
Sbjct: 4997 R---RRSRDSICALE---FQQELKD-REVLDGDTIHFDVRIT--GRPEPKVVWYKDDKEL 5047

Query: 2552 KMGSR--FRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQ 2609
                R  F +  + G  +L I     +D G Y C A N AG               +++ 
Sbjct: 5048 VESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAG-------TISCQAELLVED 5100

Query: 2610 AMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPR 2669
               PE  +    K A     P+       ++AP+FT  LK    + +G     +A+V   
Sbjct: 5101 V--PEEEDTTDSKPAPAT-APK--PAKRKEEAPVFTALLKD-RTIKDGDAARFDARVIGF 5154

Query: 2670 TDPNLKIEWFKNGVTLTTGA--RLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAV 2727
              P+  + W +    +T  +   +K+  +  + +L I      DSG+Y C A N  G+  
Sbjct: 5155 PTPD--VTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDT 5212

Query: 2728 STASIKIE 2735
            +   + +E
Sbjct: 5213 TVGHLFVE 5220



 Score =  119 bits (287), Expect = 5e-26
 Identities = 171/805 (21%), Positives = 303/805 (37%), Gaps = 79/805 (9%)

Query: 1278 DTQNEQAIEQIQLLEDAARRTKQVREDITVMQA-PQFSRALHNIETVEGTNVHLECRLQP 1336
            D   ++ +E+  LL + A R  Q  ++ T     P F +        EG       ++  
Sbjct: 4483 DEPAKEPVEEEALLPETASRADQTPDEPTAESGEPVFVQKPETCRLKEGDTARFNVKVN- 4541

Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFR-PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAV 1395
             G     V+WF   + I+   R R    +    +L ++ +  ED+GVY C A N  G   
Sbjct: 4542 -GSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSIS 4600

Query: 1396 TSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESV---TIKPRFVTRPKS 1452
                L V  ++D +     P+ +E     E T    +T++   S       P+ V   + 
Sbjct: 4601 CEAELIVDIEEDEL--DAEPTEVEPAP-AEPTPTKIQTEVSKPSKREPAPAPKPVFASEL 4657

Query: 1453 IENVI-EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIA 1511
            I+  + EG+++  + KL    +   +V W+++ + +   HR   I       L I  +  
Sbjct: 4658 IDKQVKEGENLSLDVKLPQ--EYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSI 4715

Query: 1512 EDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVD 1571
            +D  +Y   A N  GT    C +       + +      G    QV              
Sbjct: 4716 KDEAVYKVVATNASGTTSCDCEVLVEERIKVPQIANIRGGSRLSQV-------------- 4761

Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631
                 AP      K+  ++E   A  E R        L + W+ N + +K G R   +++
Sbjct: 4762 -----APEFMEQCKSTTVQENGTAIMEVR--ATGSQPLSIRWFKNQQTIKYGGRIKMSSD 4814

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691
                 L I     +D G Y C   N  G A    +  V    S   +    G+ P+    
Sbjct: 4815 GEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPPK---T 4871

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751
              T   +   A+  ++T       P+ ++ V        E  +I   +   ++EW ++  
Sbjct: 4872 RGTKPKKSSGAKPSIVT-------PLANMEVFSGDDVMLE--VISGPEQVKKIEWFKDNE 4922

Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLE 1811
             I    R T   +     L +     +D G + C  +N+ G A  S+ + V+       E
Sbjct: 4923 LIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSE 4982

Query: 1812 SQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPY 1871
            S  + A  +  ++E   R + R+ +      A  F  +L    ++ +G + H++ RI   
Sbjct: 4983 SSADEATDRNARIE---RRRSRDSI-----CALEFQQELK-DREVLDGDTIHFDVRITGR 5033

Query: 1872 PDPNMRVEWYFNGKVLQSGHR--YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929
            P+P  +V WY + K L    R  + +  + G  +L I     +D G+Y C A N  G   
Sbjct: 5034 PEP--KVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTIS 5091

Query: 1930 SSIRLNVQS--KESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNA 1987
                L V+   +E    DS+   A          +  K A + +    E P F   +K+ 
Sbjct: 5092 CQAELLVEDVPEEEDTTDSKPAPA----------TAPKPAKRKE----EAPVFTALLKDR 5137

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV-QQGH-RFKTTYDFGYVALDILYAYAE 2045
             + +G     +A +  +  PT  V W    + +    H   K  ++    +L I     +
Sbjct: 5138 TIKDGDAARFDARV--IGFPTPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYK 5195

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVD 2070
            D+G Y C A N+ G+  T   + V+
Sbjct: 5196 DSGVYKCIAKNSAGQDTTVGHLFVE 5220



 Score =  119 bits (286), Expect = 7e-26
 Identities = 89/318 (27%), Positives = 144/318 (45%), Gaps = 33/318 (10%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            S P   QK +     EG   +F+V+LS  PRP V WFK+  ++ +  +  I         
Sbjct: 1468 SRPIFQQKLKAVSTIEGESTRFEVKLSAMPRPTVEWFKSSSQIYDGGRFTI--------- 1518

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
                T++ +SG Y L+ E+ N  I  +G       T   V       +T      ++  +
Sbjct: 1519 ----TEEENSGVYVLVIEDTN--IEDAG-------TYKVVAYNNLGKVT------SQALL 1559

Query: 384  EISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
             ++E    P+F+   +   + TEG       RV G+P PE+ WF  DR +          
Sbjct: 1560 RVNEVLTVPEFMDKAEGPIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKS 1619

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV--APKFVERFSTL 500
             ++    + ++++ L DSG+  CVARNK+G ++    L+V +K++V+  AP  +    + 
Sbjct: 1620 RDN-KFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDV-QKKKVIGNAPDIITHLISK 1677

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             V+EG  V L     G P P I W KDG+       +    DG  +++    A+  D   
Sbjct: 1678 EVKEGGTVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGE 1737

Query: 561  YQCTAQNVAGSTATRARL 578
            Y+C A N  GS  + ARL
Sbjct: 1738 YKCVATNPLGSAQSSARL 1755



 Score =  117 bits (282), Expect = 2e-25
 Identities = 139/561 (24%), Positives = 220/561 (39%), Gaps = 67/561 (11%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +M  E    +P  +  LKN E+ EG  A  E R+  V     +V WY +N+PL    ++ 
Sbjct: 3969 EMEPEFEGISPRFSVKLKNQEVIEGSTARLECRI--VGSPVPEVRWYRDNEPLIESEKYQ 4026

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAV-TSGIAIVHSKKSIYLESQHEGALP 1686
               +    AL +     ED G Y   A N  G  V T+ I++ H       ++  E  + 
Sbjct: 4027 MEQDGDHFALIVKDVSEEDDGHYKAVARNIAGRDVCTADISVKHP------DTDEESDID 4080

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
             +    D    +   ++ +     P   + ++D  V E  +  F  R      PK  V W
Sbjct: 4081 AV----DARPLESKPSKPKTEIPKPEIVLGLRDRFVVEGMSVRFNCRT--TSQPKPYVTW 4134

Query: 1747 LRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             ++G P+ +  R       G  +L +K     D+G Y C   N  G+A TS+ L      
Sbjct: 4135 FKDGQPLASYGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHL------ 4188

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
                          +++L  S     R  V   V   PRF  +L G   +  G +     
Sbjct: 4189 -------------TVEELPKS-----RPSV---VASPPRFQEELKGVITVV-GTTTKLSV 4226

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND----FGFAALDILTVYGEDSGEYTCKAI 1922
             I  +P P   +EWY + + +  G R R   D    F   +L I  V   D G Y C A 
Sbjct: 4227 PIIGHPTPV--IEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAK 4284

Query: 1923 NNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS-RYKRAVQDDSFVV---EKP 1978
            N  G   SS  + V  KE    DS  E A+   +   D++ R +      S  +   E P
Sbjct: 4285 NKSGTDFSSATVKV--KELDDEDSIQEGAMSLPKSTSDEALRMEDIPVAQSTPLKRGEPP 4342

Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
            +F + +++  + E         +    DPT   EW    +P+  G R+    D     L+
Sbjct: 4343 EFIRKLRDQFIQEKETARFVCRVIGRPDPTY--EWLRGDKPITDGGRYTIMSDDEGQTLE 4400

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA----------KSGLYLDTLDEQRLKKI 2088
            I     ED G Y C +TN+ G   TT+ + V+A          K  +   ++DE+ + + 
Sbjct: 4401 ITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPISKNIEKLLIKAASMDEESMSQA 4460

Query: 2089 QELEKYERPKPIEEEQPGQRP 2109
                  E P+ + E +P  +P
Sbjct: 4461 LAKAIAESPELLGEPEPESKP 4481



 Score =  117 bits (282), Expect = 2e-25
 Identities = 177/772 (22%), Positives = 302/772 (39%), Gaps = 100/772 (12%)

Query: 3407 RKDTSVEEEKGKA--PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLK 3464
            R D + +E   ++  PVF V       L+EG+ A F  ++  + +P   V+W+   + ++
Sbjct: 4502 RADQTPDEPTAESGEPVF-VQKPETCRLKEGDTARFNVKVNGSPEPF--VDWFLGRRMIE 4558

Query: 3465 AGSRFRTF-CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
               R R    D G   L I     ED+G Y C A N+ G     A + V      I E +
Sbjct: 4559 EDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVD-----IEEDE 4613

Query: 3524 LPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP-----PEFTTTPSDLILSENSSAHFE 3578
            L    E T  + A  E     + T   +     P     P F +   D  + E  +   +
Sbjct: 4614 LDA--EPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSLD 4671

Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
             +L    +    V W+ + K L    R+  I       L I GV  +D  +Y   ATN  
Sbjct: 4672 VKL--PQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNAS 4729

Query: 3639 GEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFT 3698
            G  +  C++ V+ R   I  PQ+ ++ + G+   Q   E + + +  T++          
Sbjct: 4730 GTTSCDCEVLVEER---IKVPQI-ANIRGGSRLSQVAPEFMEQCKSTTVQ---------- 4775

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDID 3758
                      E G    + R    G   + I WF N +    G R+   +D     L I 
Sbjct: 4776 ----------ENGTAIMEVRA--TGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKIS 4823

Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISD 3818
             +  +D G Y C  +NK G+A   A +T        +E  +  G  G       + R   
Sbjct: 4824 PVEKKDEGLYMCVISNKAGTADCEALLT--------VEPMVSDGEDGATHGSPPKTR-GT 4874

Query: 3819 APKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878
             PK+       P  +T + +  V   + V  E    P++  K  IEW+++ +L+    R+
Sbjct: 4875 KPKKSS--GAKPSIVTPLANMEVFSGDDVMLEVISGPEQVKK--IEWFKDNELIRDRPRF 4930

Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938
                +    +L I     +D G + C  +NDFG     A I       ++ +++      
Sbjct: 4931 TVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEI-------LVEEDEESYSES 4983

Query: 3939 RSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLA 3998
             ++  T   A I++  S      D +  ++ +Q  +          +++ +T  F+ ++ 
Sbjct: 4984 SADEATDRNARIERRRSR-----DSICALEFQQELK-------DREVLDGDTIHFDVRIT 5031

Query: 3999 PVGDPNMKVEWFFNGKPLLHKNR--FTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGM 4056
              G P  KV W+ + K L+   R  F    + G  ++       +D G+Y C A N  G 
Sbjct: 5032 --GRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGT 5089

Query: 4057 DETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSL 4116
               +A +       +V D  +P+     E   + + +    P+    + +A   PVF +L
Sbjct: 5090 ISCQAEL-------LVED--VPEE----EDTTDSKPAPATAPKPAKRKEEA---PVFTAL 5133

Query: 4117 PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS--RYKLTYDGMYH 4166
                T+++G+ ARF  RV G P P V WL     I   S    K  ++G  H
Sbjct: 5134 LKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALHEGEVH 5185



 Score =  117 bits (281), Expect = 3e-25
 Identities = 112/515 (21%), Positives = 202/515 (39%), Gaps = 42/515 (8%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P FE++ ++    +G + +   ++ G P P + WT+    + + N    +  E+     L
Sbjct: 492 PRFEKMKESFTVVEGESVELVARVTGKPAPEIEWTKDGKTVRKTNNVDTK--ERDDQAVL 549

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            I++    D G Y CTARN+ G A  +  +  +               R V  T    A 
Sbjct: 550 TIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAV 609

Query: 192 ------GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
                 G    T E  +   +V  +  T     D     T +     +      I +  +
Sbjct: 610 LSCTISGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNEL 669

Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
           G ++ +   ++       + P+   K +  K  EG + Q  V++ G P+P + W++    
Sbjct: 670 GSAESKTKLKVIA----FARPEFRTKLKPVKAVEGEEVQLDVKVEGYPKPDIEWYRGTTM 725

Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
           ++ S + +++             ++ + G Y+L+       +  +G + V +   S    
Sbjct: 726 IVESGRFKVME------------EEEEDGLYSLVISKLQ--LDDTGTIKVVATNASGKAT 771

Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDV-TEGKMTRFDCRVTGRPYPEVT 424
            R+              +E+ E+  AP+F    +   V TEG       RV   P  +V 
Sbjct: 772 SRAD-------------LEVKEREFAPEFEGDEEGPIVVTEGNEVSIQLRVKANPNADVD 818

Query: 425 WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-I 483
           WF + R I +     I       H L I   +L D+GV  C A N+ G+ +    + V +
Sbjct: 819 WFKDGRPIYESTKRDIK-RRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQV 877

Query: 484 EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
           +  +  AP  + +   +   EGE   L     G P P   W +DG+ I  +  ++I T  
Sbjct: 878 KGPKGEAPIILSKLRPVETEEGEETKLKCTFTGKPAPTCEWTRDGIRIRSSRMVQIDTTE 937

Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +STL I      D   Y+CT +N  G+ +T A +
Sbjct: 938 DSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEV 972



 Score =  116 bits (280), Expect = 4e-25
 Identities = 83/288 (28%), Positives = 134/288 (46%), Gaps = 21/288 (7%)

Query: 197  TTEQSRQTQKVAYTNGTDHSS-----TDDFKVDTFEYRLLREVSFRESITKRYVGES-DV 250
            T+E +R T  +A     D         +DF + +    +L E    ES ++    E+ D 
Sbjct: 4933 TSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEED-EESYSESSADEATDR 4991

Query: 251  QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
                E  RS   +   +  Q+ ++ ++ +G    F V+++G P P+V W+K+ + L+ S 
Sbjct: 4992 NARIERRRSRDSICALEFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVES- 5050

Query: 311  KHEIITTHNHT---TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES-PTESYVQDQ 366
            K  I  +   T   +L ++     D G Y  +A NP G I     L VE  P E    D 
Sbjct: 5051 KRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEEDTTDS 5110

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
            +    T  +  + +E         AP F  + +DR + +G   RFD RV G P P+VTW 
Sbjct: 5111 KPAPATAPKPAKRKEE--------APVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWL 5162

Query: 427  INDRQIR-DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
              D+QI  + + H   ++E   H+L+IT     DSGV  C+A+N +G+
Sbjct: 5163 REDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQ 5210



 Score =  113 bits (273), Expect = 2e-24
 Identities = 192/774 (24%), Positives = 308/774 (39%), Gaps = 108/774 (13%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
            EV EG P+ L   +     PT  VEW+   R  ++    K   +     L I  A  ED+
Sbjct: 3637 EVWEGAPIKLIVQIKGKPAPT--VEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDS 3694

Query: 2048 GTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQ 2107
            G Y C+ATN  G    T  V V+           EQ++          R +PI    PG 
Sbjct: 3695 GNYRCQATNDAGTVTKTFKVVVN-----------EQKVVM--------RRQPIP---PGA 3732

Query: 2108 -RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTT-HDFG 2165
             +P FL  +  LE + EG  A    RV+ + +P   IDW+ + + IR G R      + G
Sbjct: 3733 VKPSFLQRMQDLE-IVEGSAARLCVRVQGVPEPE--IDWYKDNRVIREGGRVEFEFEEDG 3789

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGH------RNIILD-TQHPNGLE 2218
               L I      D G Y C  +N  G+A  +  L +  H       +  LD        E
Sbjct: 3790 LCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARE 3849

Query: 2219 KIRQLEAQGHSTRIEVE-EPKI--SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLR 2275
               +L +   S   + E  PK   +PP F   LR    V EG    F  +V  +    ++
Sbjct: 3850 STIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNR-EVKEGGVTKFASRV--ISKAPIK 3906

Query: 2276 IEFYHNGKALQSA-ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
            +E+Y + + + S   R     D    +++I +    D G Y+    N  G        TV
Sbjct: 3907 VEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYG--------TV 3958

Query: 2335 TAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTA 2394
             +K            L  + E+E       PE  E ++   P F+  L+N + I EG TA
Sbjct: 3959 ESKAY----------LNVLPEME-------PEF-EGIS---PRFSVKLKNQEVI-EGSTA 3996

Query: 2395 HFDCRLIPVGDPTLKVEWFR-NEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453
              +CR+  VG P  +V W+R NE LIE S +     D  + ++ +  V +ED+G Y   A
Sbjct: 3997 RLECRI--VGSPVPEVRWYRDNEPLIE-SEKYQMEQDGDHFALIVKDVSEEDDGHYKAVA 4053

Query: 2454 SNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKK--IQKLE-QPHERRSEEPDREFEKPIF 2510
             N+ G                 +  +HP+  ++  I  ++ +P E +  +P  E  KP  
Sbjct: 4054 RNIAGRDVCTA----------DISVKHPDTDEESDIDAVDARPLESKPSKPKTEIPKP-- 4101

Query: 2511 TQVLTGPSELW--EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTL 2568
             +++ G  + +  EG    +  R      P     W+ +G  L    R+  T   G  +L
Sbjct: 4102 -EIVLGLRDRFVVEGMSVRFNCRT--TSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQSL 4158

Query: 2569 DINSVVANDAGLYMCKAIN---RAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAA 2625
             I      DAG+Y C+  N   +AG                +  A  P   E+++     
Sbjct: 4159 TIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPSV-VASPPRFQEELKGVITV 4217

Query: 2626 MNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPR-TDPNLKIEWFK--NG 2682
            +    ++ V       P+   + K   +++EG  +  E   E R T  +L I   +  + 
Sbjct: 4218 VGTTTKLSVPIIGHPTPVIEWY-KDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDE 4276

Query: 2683 VTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                  A+ KS  DF   T+ +  L ++DS     +    L ++ S  ++++ED
Sbjct: 4277 GRYKCVAKNKSGTDFSSATVKVKELDDEDS---IQEGAMSLPKSTSDEALRMED 4327



 Score =  113 bits (273), Expect = 2e-24
 Identities = 194/848 (22%), Positives = 321/848 (37%), Gaps = 102/848 (12%)

Query: 2608 DQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVE 2667
            D+  +    E+  L E A          T     P+F    ++  +L EG       +V 
Sbjct: 4483 DEPAKEPVEEEALLPETASRADQTPDEPTAESGEPVFVQKPETC-RLKEGDTARFNVKVN 4541

Query: 2668 PRTDPNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
               +P   ++WF     +    R++    D G  +L I  +  +D+G+Y C A N  G  
Sbjct: 4542 GSPEPF--VDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSI 4599

Query: 2727 VSTASIKI---EDRHWLLGESLHPDSLDRIGA-LXXXXXXXXXXXXXXXXXXVFISHLNN 2782
               A + +   ED        + P   +     +                  VF S L +
Sbjct: 4600 SCEAELIVDIEEDELDAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELID 4659

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
               KEG+N+  +  V+  ++   ++ W+ ++K L    R           L I     +D
Sbjct: 4660 KQVKEGENLSLD--VKLPQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKD 4717

Query: 2843 SGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPS 2902
              +Y   ATN+ G  TTS    C  D  +  +          E ++  + A +  G R S
Sbjct: 4718 EAVYKVVATNASG--TTS----C--DCEVLVE----------ERIKVPQIANIRGGSRLS 4759

Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
                    PE++    +      G  +    +V       L I W+ N + ++ G R K+
Sbjct: 4760 -----QVAPEFMEQCKSTTVQENGTAIM---EVRATGSQPLSIRWFKNQQTIKYGGRIKM 4811

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022
            +SD    TL +  V ++D G+Y C   NK G A   + +           T  P  ++G 
Sbjct: 4812 SSDGEHCTLKISPVEKKDEGLYMCVISNKAGTADCEALL-----------TVEPMVSDGE 4860

Query: 3023 EKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVI 3082
            +   +   S  K  G +P   +G  P   T   ++ ++  G     E  +I   +Q   I
Sbjct: 4861 DGATH--GSPPKTRGTKPKKSSGAKPSIVTPLANM-EVFSGDDVMLE--VISGPEQVKKI 4915

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL---- 3138
            EWF + + I    R           L I      D G + C   N +G A  S ++    
Sbjct: 4916 EWFKDNELIRDRPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEE 4975

Query: 3139 -----------ECVDKSKGQKPR----------FTTHIQNIEGLKDGQSAHFECTVVPVD 3177
                       E  D++   + R          F   +++ E L DG + HF+  +    
Sbjct: 4976 DEESYSESSADEATDRNARIERRRSRDSICALEFQQELKDREVL-DGDTIHFDVRIT--G 5032

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
             P+ K+ WY + + +  S RI  VS+   G   L I      D G+Y C A N  G    
Sbjct: 5033 RPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAG---- 5088

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQG-AQQQTPSTPSAEPPKFITQIQDVTKL 3294
              TI+C        E L  D   +    +S    A    P+    E P F   ++D T +
Sbjct: 5089 --TISCQA------ELLVEDVPEEEDTTDSKPAPATAPKPAKRKEEAPVFTALLKDRT-I 5139

Query: 3295 VEGQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGHRY-RTFHDFGIVILDILYCYEENS 3352
             +G +A F+AR++    PD  V W    K++ P+ H + +  H+  +  L I     ++S
Sbjct: 5140 KDGDAARFDARVIGFPTPD--VTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYKDS 5197

Query: 3353 GEYECVATNKLGRDSTKANLKCTSKE-NLILDSQLPRGMEGGLEKL-QTLEDSMVRRKDT 3410
            G Y+C+A N  G+D+T  +L     E   I   Q P     GL ++ + L   +      
Sbjct: 5198 GVYKCIAKNSAGQDTTVGHLFVEGPEFKPIKGVQKPERKSSGLARIEEVLTLKLYTATSD 5257

Query: 3411 SVEEEKGK 3418
             + EE GK
Sbjct: 5258 FLSEETGK 5265



 Score =  113 bits (272), Expect = 3e-24
 Identities = 118/522 (22%), Positives = 197/522 (37%), Gaps = 45/522 (8%)

Query: 65   RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
            RP    P I   + K+    +G  A+ E  + G PTP + W R    + E  +  +R   
Sbjct: 2251 RPEGTEPNIVSGL-KSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRR--VRSTL 2307

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI------QPEGXXXXXXXXXXXXX 178
            + G   L+I +    D G Y C  RN  G    S ++      +PE              
Sbjct: 2308 ENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGD 2367

Query: 179  YRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE 238
                   V+   Y    +    +R   +  +        T  + +   E  +  +    +
Sbjct: 2368 RAKFEVRVKGYPYPEVEWYHGSNRILDEDRF-EIESVKETGYYSLTVGEV-VQEDAGMYK 2425

Query: 239  SITKRYVGESDVQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
             I     G+S  +   E+ +R   P       + P    + EG +   +V L  NP+P+V
Sbjct: 2426 CIAVNKAGKSTCRADLEVNERQFAPEFETGEERGP--IVVPEGGETTLKVTLRANPKPQV 2483

Query: 298  TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
             W+K+G+    + + ++ +  N   L++ N +  DSG Y   A N  G    S  + VE 
Sbjct: 2484 IWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADKSFTIRVEV 2543

Query: 358  PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
            P                  + T E   I ++          Q  D  EG+  + +CRV+G
Sbjct: 2544 P------------------KPTGEEPTILQR---------LQPVDTIEGEAIKMECRVSG 2576

Query: 418  RPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            +P P +TW  +      D   K    +     L I +V L D G+  C A+N SG     
Sbjct: 2577 KPEPTITWLKDGLVFLTDNRIKTYF-DGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSS 2635

Query: 478  CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
              L V+E+E    P+ +E+   ++   GE  +   R  G+P P + W +    I      
Sbjct: 2636 AELTVLERE--ARPRILEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHY 2693

Query: 538  RIHTDG-GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             +  +G G  +L I      D   Y+    N +G  ++ A L
Sbjct: 2694 IVRDEGRGYFSLTIEYIDYEDEGAYKAVVINDSGEVSSTAVL 2735



 Score =  113 bits (271), Expect = 4e-24
 Identities = 99/411 (24%), Positives = 169/411 (41%), Gaps = 39/411 (9%)

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
            P++ S P I TK ++   V E E    E    G P P ++W ++   ++ S   +     
Sbjct: 1088 PIEGSAPKI-TKPLESVEVNEGEDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDG 1146

Query: 4464 TKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523
              + L+ +Q   ED   +     N  G A  +  + V    R        P F +    V
Sbjct: 1147 NVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSR--------PEFKIKMSPV 1198

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
             VT G     + +V G   + V W K   K++   R     +   YT++I     +D+G 
Sbjct: 1199 EVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGG 1258

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y CVA N+AG+    A+  V     +  P+ +T+      E+ + ++ K+          
Sbjct: 1259 YRCVATNTAGKTTSRADLTVK--EREFAPEFETRDDTIDSEVNKEVEIKVTT-------- 1308

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
                G+P            I+ S    +    D +T  I  A   D G YKC A N+AG 
Sbjct: 1309 ----GEP------------IRDSINTDVRAIGDSHTCFIVRAKLSDAGVYKCQATNAAGS 1352

Query: 4704 VTVAAKLKVTQ--PDQADNLPALT-PLRDIVVYEGQPAQFKTQITS-KIKPTIQWLREGA 4759
             + + ++KV Q  P      P +   L+   + EG  A    ++T+ K +P+I+W R+G 
Sbjct: 1353 ASRSWEVKVKQSAPKTTGEEPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGV 1412

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             I E    +M+ +G    L I +   +D G +    T   G   ++ +++V
Sbjct: 1413 KIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLV 1463



 Score =  111 bits (266), Expect = 2e-23
 Identities = 127/505 (25%), Positives = 203/505 (40%), Gaps = 46/505 (9%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +GG    +  LR NP P V W +      E  +  +R    T  + +   +I   D G Y
Sbjct: 2465 EGGETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIE--DSGSY 2522

Query: 145  TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204
             C ARN+ G A  S  I+ E               + V +T+E +A   +   + +   T
Sbjct: 2523 KCEARNKLGFADKSFTIRVEVPKPTGEEPTILQRLQPV-DTIEGEAIKMECRVSGKPEPT 2581

Query: 205  ---QKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFR-ESITKRYVGESDVQISTEIDRS- 259
                K      TD+     F  D     + R+V    E I +     S     +  + + 
Sbjct: 2582 ITWLKDGLVFLTDNRIKTYFDGDVCTLTI-RDVKLGDEGIYRCNAKNSSGSAHSSAELTV 2640

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            L   + P+I +K ++     G  A F++++SG+P P V W++         + E ITT  
Sbjct: 2641 LEREARPRILEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYR---------RDEEITTKG 2691

Query: 320  HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRET 379
            H  +R         G+++L  E          Y+  E    +Y    ++  I D+ +  +
Sbjct: 2692 HYIVR-----DEGRGYFSLTIE----------YIDYEDEG-AY----KAVVINDSGEVSS 2731

Query: 380  EERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
               + ++E  + P F+ + +   +T  EG        V GRP P V  F+ D       +
Sbjct: 2732 TAVLRLAEGMIEPSFIGI-EFEPITAYEGSDIDLTFYVKGRPLPTVE-FLKDEVPVFKSD 2789

Query: 438  HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV----VAPKF 493
               L +    H L ++++ + DS     VA+NK+G       L V  K  +     AP+ 
Sbjct: 2790 RTELTSNGNRHTLYLSDLAVRDSATYKAVAKNKAGVARRSVELLVKPKRGLKPGEAAPEI 2849

Query: 494  VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
            V+R     V EG    L  R  GTPTP I W K  +P+ PN  + I   G    L+    
Sbjct: 2850 VQRLKACEVPEGSSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLET 2909

Query: 554  KASDAAWYQCTAQNVAGSTATRARL 578
            +A D   Y   A+N  GS +T A L
Sbjct: 2910 EARDEGRYMLVAKNHLGSVSTSAEL 2934



 Score =  110 bits (265), Expect = 2e-23
 Identities = 173/779 (22%), Positives = 286/779 (36%), Gaps = 81/779 (10%)

Query: 627  PGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT 686
            P E       P F+   ++    EG    F  ++   G P   ++W    + IE   R  
Sbjct: 4507 PDEPTAESGEPVFVQKPETCRLKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEEDDRIR 4564

Query: 687  -SIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745
                  G  SL ++ ++ +D+G Y C A +  G    +A L V      +     P  ++
Sbjct: 4565 IEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEE--DELDAEPTEVE 4622

Query: 746  YIQQLEDYSKYQHQESI----EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPT 801
                    +K Q + S     E   + +P F   L D  +++EG N   + +L    +  
Sbjct: 4623 PAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDK-QVKEGENLSLDVKLP--QEYK 4679

Query: 802  MRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIR 861
              V WY+D + +    RIT I       L I  +  +D   Y V A N  G       + 
Sbjct: 4680 AEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCDCEVL 4739

Query: 862  VAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISI 921
            V  R  V     I    R                         S   PEF    K   ++
Sbjct: 4740 VEERIKVPQIANIRGGSRL------------------------SQVAPEFMEQCKST-TV 4774

Query: 922  KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
            +E G A  E R    G   L + W K+ + ++   RI    +  +  L I  V   D G 
Sbjct: 4775 QENGTAIMEVRAT--GSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGL 4832

Query: 982  YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            Y C   N  G A   A LT+   + ++++ +             +   ++ T+ +     
Sbjct: 4833 YMCVISNKAGTADCEALLTV---EPMVSDGEDGA-------THGSPPKTRGTKPKKSSGA 4882

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            KP  + PL    ++  G     E    P+      +EW+ + + I    R     +    
Sbjct: 4883 KPSIVTPLANM-EVFSGDDVMLEVISGPEQ--VKKIEWFKDNELIRDRPRFTVTSEDTRH 4939

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161
             L IA+   +D G++  V  N  G A  SA + VE      + S      ++   IE  +
Sbjct: 4940 TLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIERRR 4999

Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221
              + +  +E        F Q L +   V +G  IH + R+   G P  +V W+ + + + 
Sbjct: 5000 SRDSICALE--------FQQELKDRE-VLDGDTIHFDVRIT--GRPEPKVVWYKDDKELV 5048

Query: 1222 VGSR--FKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDT 1279
               R  F +  + G  +L I  AT  D G+Y   A N  G+    A +       +V D 
Sbjct: 5049 ESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAEL-------LVEDV 5101

Query: 1280 QNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGD 1339
              E+     +     A +  + +E+     AP F+  L +    +G     + R+  +G 
Sbjct: 5102 PEEEDTTDSKPAPATAPKPAKRKEE-----APVFTALLKDRTIKDGDAARFDARV--IGF 5154

Query: 1340 QTMRVEWFCNGKPIK-TGH-RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
             T  V W    K I    H   +  +E +  +L +     +DSGVY C A N  G+  T
Sbjct: 5155 PTPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTT 5213



 Score =  110 bits (264), Expect = 3e-23
 Identities = 65/193 (33%), Positives = 99/193 (51%), Gaps = 5/193 (2%)

Query: 382  RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            ++ + E  + P F    QD DV EG   +F   V+G+P  +V W   D+++R+     + 
Sbjct: 3517 QLTVKEALIIPHFDHPIQDLDVIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLE 3576

Query: 442  VN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE--RFS 498
             + E+  + L ITN   +DSG  TC+ARNK+GE     RL V  KE++V P F E     
Sbjct: 3577 EDRETQMYFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAV--KEKMVTPSFAEGDADE 3634

Query: 499  TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
               V EG P+ L  +  G P P + W K+         +++ T+G    L IP+A+  D+
Sbjct: 3635 PCEVWEGAPIKLIVQIKGKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDS 3694

Query: 559  AWYQCTAQNVAGS 571
              Y+C A N AG+
Sbjct: 3695 GNYRCQATNDAGT 3707



 Score =  109 bits (263), Expect = 4e-23
 Identities = 180/808 (22%), Positives = 305/808 (37%), Gaps = 96/808 (11%)

Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
            ++  +EP  E  +P+F Q       L EG  A +  +V   G P    +W++    ++  
Sbjct: 4504 DQTPDEPTAESGEPVFVQK-PETCRLKEGDTARFNVKVN--GSPEPFVDWFLGRRMIEED 4560

Query: 2555 SRFRTTH-DFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQA--- 2610
             R R    D G  +L I  +   DAG+Y C A N  G                +D     
Sbjct: 4561 DRIRIEEGDVGECSLVIMDIDREDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTE 4620

Query: 2611 MRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPR 2669
            + P   E    K       P    +      P+F + L   DK V EG+++ L+ ++ P+
Sbjct: 4621 VEPAPAEPTPTKIQTEVSKPSKR-EPAPAPKPVFASEL--IDKQVKEGENLSLDVKL-PQ 4676

Query: 2670 TDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729
             +   ++ W+++   L    R+       L  L+I  +   D  +Y   ATN  G     
Sbjct: 4677 -EYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASGTTSCD 4735

Query: 2730 ASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGD 2789
              + +E+R  +      P   +  G                     F+    +   +E  
Sbjct: 4736 CEVLVEERIKV------PQIANIRGG-----------SRLSQVAPEFMEQCKSTTVQENG 4778

Query: 2790 NIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCK 2849
                E     S+   L I WF N + +  G R K + D  + +L I+   ++D G+Y C 
Sbjct: 4779 TAIMEVRATGSQP--LSIRWFKNQQTIKYGGRIKMSSDGEHCTLKISPVEKKDEGLYMCV 4836

Query: 2850 ATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYP 2909
             +N  G+A     L           T  P    G +        +  +G +P    +   
Sbjct: 4837 ISNKAGTADCEALL-----------TVEPMVSDGEDGATHGSPPK-TRGTKPK--KSSGA 4882

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            KP  + P+ A  ++  G  + LE    P+     KIEW+ + +++    RF +TS+    
Sbjct: 4883 KPSIVTPL-ANMEVFSGDDVMLEVISGPEQVK--KIEWFKDNELIRDRPRFTVTSEDTRH 4939

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLE 3029
            TL +      D GI+ C   N  G A  S+ +     +     +   + T+   +I+   
Sbjct: 4940 TLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIE--- 4996

Query: 3030 DSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGK 3089
                    ++   D+    EF    KD  ++ +G   H++  +  TG     + W+ + K
Sbjct: 4997 --------RRRSRDSICALEFQQELKD-REVLDGDTIHFDVRI--TGRPEPKVVWYKDDK 5045

Query: 3090 TIEASHRIRTVY--AFGMVVLEILGTKTTDSGTYSCRATNKWG----QAEISV-----KL 3138
             +  S RI  V     G+  L I      D G Y C A N  G    QAE+ V     + 
Sbjct: 5046 ELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEE 5105

Query: 3139 ECVD------------KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWY 3186
            +  D            K K + P FT  +++   +KDG +A F+  V+    PD  + W 
Sbjct: 5106 DTTDSKPAPATAPKPAKRKEEAPVFTALLKD-RTIKDGDAARFDARVIGFPTPD--VTWL 5162

Query: 3187 HNGQPMRHST--RIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244
               + +  ++   +K + +     L I      DSG Y C A N  G+D T   +   G 
Sbjct: 5163 REDKQITPNSHPHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEGP 5222

Query: 3245 -----GGVYLESLQPDSLAKIRELESLQ 3267
                  GV     +   LA+I E+ +L+
Sbjct: 5223 EFKPIKGVQKPERKSSGLARIEEVLTLK 5250



 Score =  108 bits (260), Expect = 9e-23
 Identities = 82/312 (26%), Positives = 134/312 (42%), Gaps = 35/312 (11%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+I Q      ++E  +A     +SG P P   W+++  R+  S + +    +   TL +
Sbjct: 9   PQILQPLEGVDVKEDENAILSCTISGTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTI 68

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
           + T+  D G Y         C++                  R+++ T T +     R+ +
Sbjct: 69  KQTRAEDQGEYK--------CVL------------------RNEHGTATSKAPLNVRVPV 102

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
                 P F    +  D  EG+  RFD  V G P P+V W+     I      +I+    
Sbjct: 103 K-----PSFTSKMKPVDAEEGQEVRFDVHVKGSPKPDVVWYKGSTMIGTHERFQIVEAAE 157

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ERFSTLNVRE 504
            +  L+I+ V L D+     VA N  G+   +  L V  KE+  AP+F+ E    ++   
Sbjct: 158 DHVTLVISEVKLEDAETYKVVATNDVGKVTSRADLRV--KERQFAPEFIDEERGPIDATT 215

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           G+ V L     G P P ITW K+G  +  + +L I + G  + + +  AK  D A Y+C 
Sbjct: 216 GDEVTLTCSVSGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCE 275

Query: 565 AQNVAGSTATRA 576
           A+N  G  A+RA
Sbjct: 276 AENKLGK-ASRA 286



 Score =  108 bits (260), Expect = 9e-23
 Identities = 121/524 (23%), Positives = 209/524 (39%), Gaps = 47/524 (8%)

Query: 65   RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
            +P    P I +++ +     +G   K E ++ G P P ++W +     +  N+    ++ 
Sbjct: 2545 KPTGEEPTILQRL-QPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTYFD- 2602

Query: 125  QTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP-EGXXXXXXXXXXXXXYRHV 182
              GDV +L I+ +  GDEG Y C A+N  G A  S  +   E                 V
Sbjct: 2603 --GDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLEREARPRILEKLQDVDSSV 2660

Query: 183  SETVEHK--AYGTQGYTTEQSRQTQKVAYTNG---TDHSSTDDFKVDTFEYRLLREVSFR 237
             E    K    G+     +  R+ +++  T G           F + T EY    +    
Sbjct: 2661 GERAMFKIRVSGSPMPVVQWYRRDEEIT-TKGHYIVRDEGRGYFSL-TIEYIDYEDEGAY 2718

Query: 238  ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
            +++     GE  V  +  +  + G + P  I  +       EG+D      + G P P V
Sbjct: 2719 KAVVINDSGE--VSSTAVLRLAEGMIEPSFIGIEFEPITAYEGSDIDLTFYVKGRPLPTV 2776

Query: 298  TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
             + K+   +  S++ E+ +  N  TL + +    DS  Y  +A+N  G            
Sbjct: 2777 EFLKDEVPVFKSDRTELTSNGNRHTLYLSDLAVRDSATYKAVAKNKAG--------VARR 2828

Query: 358  PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
              E  V+ +R                 +     AP+ V+  +  +V EG   +  CRVTG
Sbjct: 2829 SVELLVKPKRG----------------LKPGEAAPEIVQRLKACEVPEGSSFKLRCRVTG 2872

Query: 418  RPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAF 476
             P P + W+ ++  ++   N ++++  +G+ + L        D G    VA+N  G  + 
Sbjct: 2873 TPTPTIEWYKSNMPLKP--NGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVST 2930

Query: 477  QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536
               L +IE   V  P F  R + + V EG+    + R    PT  + W K+   I  +  
Sbjct: 2931 SAEL-IIE-PSVSPPSFRHRLTAVEVDEGDETRFDVRLKKEPT-SVEWYKEQQRIFTDGH 2987

Query: 537  LRI--HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +    +    +L I   K +DA  Y+CTA N +G ++TRA L
Sbjct: 2988 FEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL 3031



 Score =  107 bits (256), Expect = 3e-22
 Identities = 142/511 (27%), Positives = 203/511 (39%), Gaps = 61/511 (11%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCD----FGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505
            P   +EWY + + +  G R R   D    F  V L I      D G Y C A N  G   
Sbjct: 4232 PTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDF 4291

Query: 3506 TTASMKVQ--GKRNIILES--QLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFT 3561
            ++A++KV+     + I E    LPK    T D+   +E     V   TP  + G PPEF 
Sbjct: 4292 SSATVKVKELDDEDSIQEGAMSLPKS---TSDEALRMEDIP--VAQSTP-LKRGEPPEFI 4345

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
                D  + E  +A F CR+I   D +   EW    KP+  G R   ++D     LEI  
Sbjct: 4346 RKLRDQFIQEKETARFVCRVIGRPDPT--YEWLRGDKPITDGGRYTIMSDDEGQTLEITD 4403

Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGII---LEPQLPSHFKSGTESI-QKLEE 3677
                D GLY C +TN  G  T + +L V+  +  I   +E  L        ES+ Q L +
Sbjct: 4404 CTVEDEGLYKCVSTNSSGTDTTTARLTVEASRRPISKNIEKLLIKAASMDEESMSQALAK 4463

Query: 3678 TLHKREEITIEDE---KP--NPPRFTVE--------------IKDNIDVPEGGPVHFD-- 3716
             + +  E+  E E   KP   P +  VE                D      G PV     
Sbjct: 4464 AIAESPELLGEPEPESKPADEPAKEPVEEEALLPETASRADQTPDEPTAESGEPVFVQKP 4523

Query: 3717 --CRVEPVGDPTMRIDWFHNGRP-----FATGSRVHTLND--------FGFIALDIDYIY 3761
              CR++  GD T R +   NG P     +  G R+   +D         G  +L I  I 
Sbjct: 4524 ETCRLKE-GD-TARFNVKVNGSPEPFVDWFLGRRMIEEDDRIRIEEGDVGECSLVIMDID 4581

Query: 3762 ARDAGEYTCRATNKWGSATTTAKITCSAKRD-IVLESQLPQGMSGEKIKELERGRISDAP 3820
              DAG Y C A N  GS +  A++    + D +  E    +    E      +  +S   
Sbjct: 4582 REDAGVYKCVAENDDGSISCEAELIVDIEEDELDAEPTEVEPAPAEPTPTKIQTEVSKPS 4641

Query: 3821 KEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            K EP  +  P F +++    V+E E +  + ++ P+E  K  + WYR+ K L   HR   
Sbjct: 4642 KREPAPAPKPVFASELIDKQVKEGENLSLDVKL-PQE-YKAEVAWYRDDKKLEDDHRITI 4699

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            +       L I  V  +D   Y   A N  G
Sbjct: 4700 IAAGDLHCLTIFGVSIKDEAVYKVVATNASG 4730



 Score =  105 bits (252), Expect = 9e-22
 Identities = 110/504 (21%), Positives = 191/504 (37%), Gaps = 44/504 (8%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +GG    E  + G P P + W +         +    ++     V+    Q    D+GEY
Sbjct: 1681 EGGTVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQ--GFDDGEY 1738

Query: 145  TCTARNQYGEAICS----VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQ 200
             C A N  G A  S    V +  +                     V  K+Y       E 
Sbjct: 1739 KCVATNPLGSAQSSARLTVTVPSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKP--EVEW 1796

Query: 201  SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIST-EIDRS 259
             R T K+  T+   H  T+ ++ D     ++   +  ++   + V  ++   +T   D +
Sbjct: 1797 YRGTTKI--TDSLRHQITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLT 1854

Query: 260  -LGPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
             +    PP          +  +EG D      ++G P P V+W+K+G+ +++S K E   
Sbjct: 1855 VIEKQQPPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQE--- 1911

Query: 317  THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
                        ++ D  H  +     N  +  +G         SY  +  ++  T T+ 
Sbjct: 1912 ----------TRKRGDESHLVVF----NAKMEDAG---------SYKCEANNKLGTVTKT 1948

Query: 377  RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
               +  +  + +  AP F       +V EG   +    ++G P P V W  +   + +DY
Sbjct: 1949 YNVKV-MSTAPEGQAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVKWTRDGIPVFEDY 2007

Query: 437  NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER 496
               +  +      L+I NVT  D GV  C  +N+ G T     + VI  ++ + P F ++
Sbjct: 2008 RISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTT--TTVQVIVTQRSIRPIFGQK 2065

Query: 497  FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-HTDGGASTLDIPRAKA 555
               +  R GE V    +  GTP P +T+ ++   I       I   + G   L I   + 
Sbjct: 2066 MKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRP 2125

Query: 556  SDAAWYQCTAQNVAGSTATRARLY 579
             DA  YQC A N AG   ++  L+
Sbjct: 2126 EDAGEYQCIAVNGAGEVTSKGYLH 2149



 Score =  105 bits (251), Expect = 1e-21
 Identities = 147/624 (23%), Positives = 256/624 (41%), Gaps = 94/624 (15%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P ++ EG       +I+  P P   VEW+   +  +     +   +     L I     E
Sbjct: 3635 PCEVWEGAPIKLIVQIKGKPAPT--VEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPE 3692

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDS 1972
            DSG Y C+A N+ G    + ++ V  ++ ++R                    ++ +   +
Sbjct: 3693 DSGNYRCQATNDAGTVTKTFKVVVNEQKVVMR--------------------RQPIPPGA 3732

Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
                KP F + +++ E+ EG    L   +  V +P   ++WY + R +++G R +  ++ 
Sbjct: 3733 V---KPSFLQRMQDLEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEE 3787

Query: 2033 -GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA---KSGLYLDTLDEQRLKKI 2088
             G   L I  A   D G Y C  +NA G+A  ++ + ++     SG+    LD    K+ 
Sbjct: 3788 DGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEA 3847

Query: 2089 QE--LEKYERPKPIEE------EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPH 2140
            +E  +E        EE      ++ G  P F   L + E +KEG    F  RV  I+   
Sbjct: 3848 RESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNRE-VKEGGVTKFASRV--ISKAP 3904

Query: 2141 LTIDWFHNGQKIRAG-HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
            + ++W+ + + I +   R+   HD    A++I      D G Y    +NK G      T+
Sbjct: 3905 IKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYG------TV 3958

Query: 2200 KVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKT 2259
            +   + N++ + +           E +G S R  V   K+     +    G+T       
Sbjct: 3959 ESKAYLNVLPEMEP----------EFEGISPRFSV---KLKNQEVI---EGST------- 3995

Query: 2260 AHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKA 2319
            A  EC++  V  P   + +Y + + L  + ++ +  D  + +L ++    ED G Y   A
Sbjct: 3996 ARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFALIVKDVSEEDDGHYKAVA 4053

Query: 2320 INALGH--CTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP--VTRQR 2375
             N  G   CT+ IS+    K     E    + ++  R LES     + EIP+P  V   R
Sbjct: 4054 RNIAGRDVCTADISV----KHPDTDEESDIDAVD-ARPLESKPSKPKTEIPKPEIVLGLR 4108

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
              F         + EG +  F+CR      P   V WF++ + +    R   T   G  S
Sbjct: 4109 DRF---------VVEGMSVRFNCR--TTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQS 4157

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            +TI   +  D G+Y C  SN+ G+
Sbjct: 4158 LTIKDCKLADAGIYKCEVSNVGGK 4181



 Score =  103 bits (248), Expect = 3e-21
 Identities = 128/507 (25%), Positives = 200/507 (39%), Gaps = 56/507 (11%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+F+   KS T  E G    E R    G   + I W KN Q+I+   R        + +L
Sbjct: 4763 PEFMEQCKSTTVQENGTAIMEVRA--TGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTL 4820

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI-ERTSQHPETLQYIQQLEDYSK 755
             +  +  +D G Y C   +  G A+ +A+L V P  +  E  + H    +          
Sbjct: 4821 KISPVEKKDEGLYMCVISNKAGTADCEALLTVEPMVSDGEDGATHGSPPK---------- 4870

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                   ++ +  +P  + PL ++ E+  G +   E    P  +   ++EW+KD   I  
Sbjct: 4871 -TRGTKPKKSSGAKPSIVTPLANM-EVFSGDDVMLEVISGP--EQVKKIEWFKDNELIRD 4926

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
              R T        +L I     +D G +    +N  G A  +A I V             
Sbjct: 4927 RPRFTVTSEDTRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEE----------- 4975

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935
            ++  Y E +                   +S    EF+  +KD+  + +G   HF+ R+  
Sbjct: 4976 DEESYSESSADEATDRNARIERRRSR--DSICALEFQQELKDR-EVLDGDTIHFDVRIT- 5031

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
             G    +V W KD + +  S RI        G  +L IK  T+ D G Y C A N  G  
Sbjct: 5032 -GRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTI 5090

Query: 994  TTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTN 1053
            +  A L +   +D+  E       +       A + +KR EE       P F   LK   
Sbjct: 5091 SCQAELLV---EDVPEEEDTT---DSKPAPATAPKPAKRKEEA------PVFTALLKDRT 5138

Query: 1054 KIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQIT--SANRIQTYHDFGYVALDIASVR 1109
             I +G +A F+ARV   P  D+T    W    KQIT  S   ++  H+    +L I    
Sbjct: 5139 -IKDGDAARFDARVIGFPTPDVT----WLREDKQITPNSHPHMKALHEGEVHSLLITEGG 5193

Query: 1110 AEDSGVYTVVARNAAGEAQLSASMTVE 1136
             +DSGVY  +A+N+AG+      + VE
Sbjct: 5194 YKDSGVYKCIAKNSAGQDTTVGHLFVE 5220



 Score =  103 bits (246), Expect = 5e-21
 Identities = 118/518 (22%), Positives = 201/518 (38%), Gaps = 48/518 (9%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRG-NPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            PI  +  +     +G  A    K+    P P + WTR    + E ++  M ++ +T   S
Sbjct: 1373 PIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKIRENSRIKMVFDGET--CS 1430

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEA--ICSVYIQPEGXX-XXXXXXXXXXXYRHVSETVE 187
            L I+     DEG Y  T  N+YG A   C V +   G                  S   E
Sbjct: 1431 LTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKLKAVSTIEGESTRFE 1490

Query: 188  HKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247
             K       T E  + + ++ Y  G   + T++     +   ++ + +  ++ T + V  
Sbjct: 1491 VKLSAMPRPTVEWFKSSSQI-YDGGR-FTITEEENSGVY-VLVIEDTNIEDAGTYKVVAY 1547

Query: 248  SDV-QISTEIDRSLGPV-SPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            +++ +++++    +  V + P+   K     +  EG D +  V++ G P+P + WFK  +
Sbjct: 1548 NNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEKTEGDDLELTVRVRGKPQPELEWFKYDR 1607

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
             L  S++    +  N  T+ V +    DSG Y  +A N  G    +  L V+   +  V 
Sbjct: 1608 TLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQ---KKKVI 1664

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
                  IT    +E +E                        G     +C V+G+P P + 
Sbjct: 1665 GNAPDIITHLISKEVKE------------------------GGTVTLECTVSGKPAPNIE 1700

Query: 425  WFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            W+ +   +R     +++    G+ A +  T+    D G   CVA N  G      RL V 
Sbjct: 1701 WYKDG--LRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVT 1758

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI---H 540
               +   P+F ++   L V EG     + R    P P + W +    I  +   +I   +
Sbjct: 1759 VPSK---PEFKQKLRPLEVVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQITEPY 1815

Query: 541  TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
                  +L I      DAA Y+C A N AG T  RA L
Sbjct: 1816 EGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADL 1853



 Score =  100 bits (239), Expect = 3e-20
 Identities = 120/522 (22%), Positives = 201/522 (38%), Gaps = 49/522 (9%)

Query: 65  RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
           RP    P I + + +     +  NA     + G PTP   W R    + E  +  ++   
Sbjct: 3   RPKGDRPQILQPL-EGVDVKEDENAILSCTISGTPTPNAEWYRDSIRVRESRR--IKSEV 59

Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184
             G  +L IKQ    D+GEY C  RN++G A     +                      +
Sbjct: 60  VNGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVPVKPSFTSKMKPVDAEEGQ 119

Query: 185 TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV----DTFEYRLLREVSFRESI 240
            V    +       + S +   V Y   T   + + F++    +     ++ EV   ++ 
Sbjct: 120 EVRFDVH------VKGSPKPDVVWYKGSTMIGTHERFQIVEAAEDHVTLVISEVKLEDAE 173

Query: 241 TKRYVGESDV-QISTEIDRSLGP--VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           T + V  +DV ++++  D  +     +P  I ++        G +      +SG P+P +
Sbjct: 174 TYKVVATNDVGKVTSRADLRVKERQFAPEFIDEERGPIDATTGDEVTLTCSVSGKPKPSI 233

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
           TW+KNG+ L +S K +I ++     + + + +  D+  Y   AEN  G    +  + V++
Sbjct: 234 TWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFDVKVKA 293

Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
           P      D  S  I  T  R     IE  E  L      VC+               VTG
Sbjct: 294 PK----GDAPSFTIDLTHVR----AIEGEESKL------VCK---------------VTG 324

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477
           +P P + W   +  +      +    E     L+I +  L D+G    VARN SG     
Sbjct: 325 KPAPTIEWLKGELPVTTSLRVRTDF-EKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSI 383

Query: 478 CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
             L V  +E+   P+  +    ++   GE V    R  G P P++ W+K    I      
Sbjct: 384 AELQV--QERSTKPEIEDSLRDVSALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERF 441

Query: 538 RIHTDGG-ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            I  +     +L I   + +DA  Y+C A N AG   + A+L
Sbjct: 442 TIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQL 483



 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 59/199 (29%), Positives = 87/199 (43%), Gaps = 7/199 (3%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + I  K  AP F+    D++V EG+  R +CRV   P P V W  + R  ++DY+  I  
Sbjct: 3422 VVIESKKPAPLFIAPLHDQEVVEGETIRLECRVRATPRPMVEWKKDGRTFKEDYH--IYT 3479

Query: 443  NESGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
               G H  L+I    + D G   C+A+NK G      +L V  KE ++ P F      L+
Sbjct: 3480 EFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV--KEALIIPHFDHPIQDLD 3537

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAST--LDIPRAKASDAA 559
            V EG+    +    G P  ++ W K    +     + +  D       L I   K +D+ 
Sbjct: 3538 VIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSG 3597

Query: 560  WYQCTAQNVAGSTATRARL 578
             Y C A+N AG      RL
Sbjct: 3598 KYTCIARNKAGENTCHGRL 3616



 Score = 96.3 bits (229), Expect = 5e-19
 Identities = 67/278 (24%), Positives = 114/278 (41%), Gaps = 6/278 (2%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-S 130
           P  E   ++     G   KF+ ++ G P P V W + K+ + +  ++++   E++ +V S
Sbjct: 395 PEIEDSLRDVSALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERFTIA--EESDEVFS 452

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVS-ETVE-- 187
           L+I+ +   D G Y C A N+ GEA     +                 +  V  E+VE  
Sbjct: 453 LIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEELIGPRFEKMKESFTVVEGESVELV 512

Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247
            +  G      E ++  + V  TN  D    DD  V T E     +        +   G 
Sbjct: 513 ARVTGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGT 572

Query: 248 SDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307
           +D+    ++       + P+I  + R  +  EG DA     +SG P P + W KNG R+ 
Sbjct: 573 ADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAVLSCTISGKPVPTIEWLKNGIRVK 632

Query: 308 NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           +S + +         L ++ T+  D G YT +  N  G
Sbjct: 633 DSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELG 670



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 8/193 (4%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            +S+  + P+F +  ++  V EG   +F  RV G P P+V WF   ++I+          E
Sbjct: 3229 LSKPLVMPEFKERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKKIKSHARFSSKAGE 3288

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF----VERFSTL 500
               + L I++V + D G   CVA N +G+     RL+V  KE++V P+     +E  + L
Sbjct: 3289 KHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV--KERMVPPEISTDVLEGPALL 3346

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
            N  EG+ + L     G P P + W KDGV I  +  + + + G   +L I      D   
Sbjct: 3347 N--EGDDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGV 3404

Query: 561  YQCTAQNVAGSTA 573
             +C A N AGS +
Sbjct: 3405 IKCVAMNPAGSAS 3417



 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 59/230 (25%), Positives = 105/230 (45%), Gaps = 12/230 (5%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH--- 320
            SPP+  ++ +      G   +  V + G+P P + W+K+ + ++   +            
Sbjct: 4203 SPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFT 4262

Query: 321  -TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESPTESYVQDQRSQYITDTQQRE 378
              +L +R+ + +D G Y  +A+N +G   +S  + V E   E  +Q+        T    
Sbjct: 4263 IVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEA 4322

Query: 379  TE-ERIEISE-----KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
               E I +++     +   P+F++  +D+ + E +  RF CRV GRP P   W   D+ I
Sbjct: 4323 LRMEDIPVAQSTPLKRGEPPEFIRKLRDQFIQEKETARFVCRVIGRPDPTYEWLRGDKPI 4382

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             D   + I+ ++ G   L IT+ T+ D G+  CV+ N SG      RL V
Sbjct: 4383 TDGGRYTIMSDDEG-QTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTV 4431



 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 58/203 (28%), Positives = 92/203 (45%), Gaps = 11/203 (5%)

Query: 3039 QPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR 3098
            QP    G  P   +  K  V++ EG+ A  E   + +G  +  +EW+ +G  ++ S R+R
Sbjct: 2248 QPKRPEGTEPNIVSGLKS-VEVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVR 2304

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
            +    G+  L I  T   D GTY C+  N  G+   S  L  +      +P F   +  +
Sbjct: 2305 STLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNII---VATRPEFKEKLTKV 2361

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQN 3216
            E + +G  A FE  V     P+  +EWYH    +    R  I++V + G+  L +     
Sbjct: 2362 E-VTEGDRAKFEVRVKGYPYPE--VEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQ 2418

Query: 3217 HDSGEYVCRAYNKYGEDFTRATI 3239
             D+G Y C A NK G+   RA +
Sbjct: 2419 EDAGMYKCIAVNKAGKSTCRADL 2441



 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 129/559 (23%), Positives = 214/559 (38%), Gaps = 57/559 (10%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+F V LK+   +EG     E RI  VG P  ++ W ++ + +  S ++       + +L
Sbjct: 3979 PRFSVKLKNQEVIEGSTARLECRI--VGSPVPEVRWYRDNEPLIESEKYQMEQDGDHFAL 4036

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ-QLEDYSK 755
             +  ++ +D G Y   A +  G              T + + +HP+T +       D   
Sbjct: 4037 IVKDVSEEDDGHYKAVARNIAG----------RDVCTADISVKHPDTDEESDIDAVDARP 4086

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
             + + S  +    +P+ +  L+D   + EG +  F  + T  S P   V W+KDG+P+ +
Sbjct: 4087 LESKPSKPKTEIPKPEIVLGLRD-RFVVEGMSVRFNCRTT--SQPKPYVTWFKDGQPLAS 4143

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
              R       G  SL I   +  DAG Y     N  G+A ++A + V         + + 
Sbjct: 4144 YGRYEVTSVAGAQSLTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKSRPSV-VA 4202

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEP 935
               R+ E+                  +   T   E+    KD   + EGG   FE   E 
Sbjct: 4203 SPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEW---YKDDREVLEGGRIRFEQDQE- 4258

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
             G  T+    ++D                  V LT       D G Y C A N  G   +
Sbjct: 4259 -GRFTIVSLTIRD------------------VRLT-------DEGRYKCVAKNKSGTDFS 4292

Query: 996  SANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSK---RTEEEVKITQKPRFLGPLKGT 1052
            SA + +    D  +  +    L K    ++A R           +K  + P F+  L+  
Sbjct: 4293 SATVKVKELDDEDSIQEGAMSLPK-STSDEALRMEDIPVAQSTPLKRGEPPEFIRKLR-D 4350

Query: 1053 NKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAED 1112
              I E ++A F  RV  + D   T EW    K IT   R     D     L+I     ED
Sbjct: 4351 QFIQEKETARFVCRVIGRPD--PTYEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVED 4408

Query: 1113 SGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEI 1172
             G+Y  V+ N++G    +A +TVE      + +I + L  K   ++E    + +   + I
Sbjct: 4409 EGLYKCVSTNSSGTDTTTARLTVEASRRPISKNIEK-LLIKAASMDEESMSQAL--AKAI 4465

Query: 1173 SKSKPVFVQPLSNPPPVSE 1191
            ++S  +  +P     P  E
Sbjct: 4466 AESPELLGEPEPESKPADE 4484



 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 61/208 (29%), Positives = 96/208 (46%), Gaps = 5/208 (2%)

Query: 373  DTQQRETEERIEISEKALAPQFVKVCQDRD--VTEGKMTRFDCRVTGRPYPEVTWFINDR 430
            D  + +   R+++ E+ + P+      +    + EG   R    VTG P P++ W+ +  
Sbjct: 3314 DAGKVQCSGRLDVKERMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDLQWYKDGV 3373

Query: 431  QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490
             IR    H  L +    ++L I  V   D+GV+ CVA N +G  +    + VIE ++  A
Sbjct: 3374 LIRRS-THISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTV-VIESKKP-A 3430

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P F+       V EGE + L  R   TP P + W+KDG     +  +    DG   TL I
Sbjct: 3431 PLFIAPLHDQEVVEGETIRLECRVRATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCTLVI 3490

Query: 551  PRAKASDAAWYQCTAQNVAGSTATRARL 578
              A+  D   Y+C A+N  G   + A+L
Sbjct: 3491 KGAQIEDEGAYECIAKNKEGRGRSVAQL 3518



 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 76/340 (22%), Positives = 137/340 (40%), Gaps = 33/340 (9%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P+  ++ +++ +QE   A  +V+ +G+    + WFKN Q +    + ++ +   H TL++
Sbjct: 4763 PEFMEQCKSTTVQENGTAIMEVRATGSQPLSIRWFKNQQTIKYGGRIKMSSDGEHCTLKI 4822

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
               +K D G Y  +  N  G       L VE P  S  +D  + + +  + R T+ +   
Sbjct: 4823 SPVEKKDEGLYMCVISNKAGTADCEALLTVE-PMVSDGED-GATHGSPPKTRGTKPKKSS 4880

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
              K   P  V    + +V  G     +         ++ WF ++  IRD     +  +E 
Sbjct: 4881 GAK---PSIVTPLANMEVFSGDDVMLEVISGPEQVKKIEWFKDNELIRDRPRFTV-TSED 4936

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ------------------ 487
              H L I   T  D G+  CV  N  G  +    + V E E+                  
Sbjct: 4937 TRHTLTIATATFDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIE 4996

Query: 488  -------VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI- 539
                   + A +F +      V +G+ +  + R  G P P++ W KD   ++ +  +   
Sbjct: 4997 RRRSRDSICALEFQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIFV 5056

Query: 540  -HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               + G  +L I +A   D   Y+C A N AG+ + +A L
Sbjct: 5057 SEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAEL 5096



 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 6/194 (3%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+F      +V++ +G   +Y+ SL   G     IEW++N + I A+ R++  +      
Sbjct: 2157 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEGLKDGQS 3166
            + +      DSG Y C+A N  G       +    K  +G +P   + ++++E +K+G+ 
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVE-VKEGEQ 2273

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A  E  V     P +  EWY +G  ++ S R+++  + G   L I  T   D G Y C+ 
Sbjct: 2274 AELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQV 2331

Query: 3227 YNKYGEDFTRATIN 3240
             N  G   T A +N
Sbjct: 2332 RNDLGRTSTSAHLN 2345



 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 67/250 (26%), Positives = 111/250 (44%), Gaps = 14/250 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F  + K+   + EG+     A +  TG  +  IEW  +GKT+  ++ + T       V
Sbjct: 492  PRFEKM-KESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAV 548

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEGLKDGQS 3166
            L I  +   DSG Y C A NK G A+++ +L+   K  KG  P   + ++ +E   +G  
Sbjct: 549  LTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEA-TEGDD 607

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A   CT+     P   IEW  NG  ++ S R K     G V L I  T+  D G+Y C  
Sbjct: 608  AVLSCTI--SGKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIV 665

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
             N+ G   ++  +         +   +P+   K++ +++++G + Q        P   I 
Sbjct: 666  RNELGSAESKTKLK-------VIAFARPEFRTKLKPVKAVEGEEVQLDVKVEGYPKPDIE 718

Query: 3287 QIQDVTKLVE 3296
              +  T +VE
Sbjct: 719  WYRGTTMIVE 728



 Score = 82.6 bits (195), Expect = 7e-15
 Identities = 73/269 (27%), Positives = 112/269 (41%), Gaps = 29/269 (10%)

Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTD--MVDEVTTQA-PICTTSLKNVEIKEGQR 1594
            ST  I  +T ++ GL +  +  D      +   +V+EV     P+    LK+V +  G+ 
Sbjct: 940  STLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNEVEKGVGPVIEEKLKDVTVMPGEE 999

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFGFVALDIMSCLPEDSGTYTCR 1653
            A F  R+        +V+W+ +   L    RF  E  + G  +L I    PED GTY C 
Sbjct: 1000 AEFSIRV----SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCL 1055

Query: 1654 AINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVF 1713
              N  G+  T     +  K++I    + + A        +T   +           AP  
Sbjct: 1056 VFNESGKVTTRAKLCI--KEAIVAPEEVDAA--------ETVPIEG---------SAPKI 1096

Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMK 1773
            T P++ + V  N+   F+   +  G P   VEW ++ V +  S RL    D     L  K
Sbjct: 1097 TKPLESVEV--NEGEDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFK 1154

Query: 1774 YVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
               PED G Y C  INE G+A T+  + V
Sbjct: 1155 QARPEDIGEYKCTVINEHGKASTTGEVKV 1183



 Score = 82.6 bits (195), Expect = 7e-15
 Identities = 81/284 (28%), Positives = 123/284 (43%), Gaps = 49/284 (17%)

Query: 2062 VTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKP-----IEEEQP-GQRPVFLTAL 2115
            V  S +   A   LY  TLD+  L + + +             ++ ++P G  P  ++ L
Sbjct: 2204 VQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGL 2263

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
             S+E +KEG++A  E  V     P  T++W+ +G +++   R R+T + G   L I  T+
Sbjct: 2264 KSVE-VKEGEQAELEFVVSGTPTP--TLEWYRDGLRVKESRRVRSTLENGIARLVITETW 2320

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE 2235
            AED GTY C+  N LG          + H NII+ T+ P   EK+         T++EV 
Sbjct: 2321 AEDMGTYKCQVRNDLGRT------STSAHLNIIVATR-PEFKEKL---------TKVEVT 2364

Query: 2236 EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295
            E                    G  A FE +V+    P   +E+YH    +    RF I  
Sbjct: 2365 E--------------------GDRAKFEVRVKGYPYPE--VEWYHGSNRILDEDRFEIES 2402

Query: 2296 --DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
              + GY SL +   V EDAG Y   A+N  G  T    + V  +
Sbjct: 2403 VKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446



 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 113/498 (22%), Positives = 193/498 (38%), Gaps = 85/498 (17%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            E T H R  + ++++   P     +  +  +V EG P+    +++  G P   ++WF   
Sbjct: 3609 ENTCHGR--LAVKEKMVTPSFAEGDADEPCEVWEGAPIKLIVQIK--GKPAPTVEWFKEK 3664

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795
            R       V    +     L I      D+G Y C+ATN  G+ T T K+  + ++ ++ 
Sbjct: 3665 RQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVNEQKVVMR 3724

Query: 3796 ESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEP 3855
               +P G                        +  P F+ +++   + E    R   RV+ 
Sbjct: 3725 RQPIPPG------------------------AVKPSFLQRMQDLEIVEGSAARLCVRVQG 3760

Query: 3856 KEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGEDF 3914
              +P+  I+WY++ +++  G R    ++  G   L I      D G Y C   N  G   
Sbjct: 3761 VPEPE--IDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAG--- 3815

Query: 3915 TKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQ--- 3971
             KA  S +     I  +    G+  S+A     A  +   S + L  DD  D +K +   
Sbjct: 3816 -KAQCSAELF---IETHGFDSGV--SDADLDFAARKEARESTIELISDDTSDEEKTEGAP 3869

Query: 3972 -----PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK-NRFTPI 4025
                 PP F   ++++  + E   TKF  ++  +    +KVEW+ + + +     R T  
Sbjct: 3870 KEEGAPPEFTLVLRNR-EVKEGGVTKFASRV--ISKAPIKVEWYKDDRLISSDWPRHTFE 3926

Query: 4026 YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIE 4085
            +D    AMN   V   D G Y    +N YG  E+KA           Y + LP+     E
Sbjct: 3927 HDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESKA-----------YLNVLPEMEPEFE 3975

Query: 4086 KIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWL 4145
             I     S ++  ++V+E S AR                       CR+ G P P V W 
Sbjct: 3976 GI-SPRFSVKLKNQEVIEGSTARLE---------------------CRIVGSPVPEVRWY 4013

Query: 4146 LNGNTIVNGSRYKLTYDG 4163
             +   ++   +Y++  DG
Sbjct: 4014 RDNEPLIESEKYQMEQDG 4031



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 67/294 (22%), Positives = 114/294 (38%), Gaps = 13/294 (4%)

Query: 71   PPIFEQIFKNA-RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            PP FE     +    +G     +  ++GNP P + W + +   +E  K  +   ++    
Sbjct: 3039 PPGFEGPDHGSYELQEGDTITLDAVVKGNPYPEIRWYKDEFLAMESKKLMLSVRDRKN-- 3096

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET---- 185
            SL +  + P D G Y C  +N+ G A  S  +  E               R V       
Sbjct: 3097 SLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKSKGIIPEFFRQLRRVEAVQGST 3156

Query: 186  --VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
               E K  G         +  +++A           +    TF      +      +   
Sbjct: 3157 ARFECKVSGHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDEGDYTCVASN 3216

Query: 244  YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
              GE+    S  + +   P+  P+  ++ +N K+ EG +AQF V++ G P P+V WFK G
Sbjct: 3217 EAGEASSHASLVLSK---PLVMPEFKERLKNIKVVEGDEAQFSVRVKGEPEPKVEWFKTG 3273

Query: 304  QRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
            +++ +  +        HT TL + +    D G Y  +A N  G +  SG L V+
Sbjct: 3274 KKIKSHARFSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVK 3327



 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 55/213 (25%), Positives = 96/213 (45%), Gaps = 25/213 (11%)

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            +  P+I    R+  + EG   +F  + +  P+P VTWFK+GQ L +  ++E+ +     +
Sbjct: 4098 IPKPEIVLGLRDRFVVEGMSVRFNCRTTSQPKPYVTWFKDGQPLASYGRYEVTSVAGAQS 4157

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +++ + +D+G Y     N  G   TS +L VE   +S                     
Sbjct: 4158 LTIKDCKLADAGIYKCEVSNVGGKAGTSAHLTVEELPKS--------------------- 4196

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
               S  A  P+F +  +      G  T+    + G P P + W+ +DR++ +    +   
Sbjct: 4197 -RPSVVASPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQ 4255

Query: 443  NESGNH---ALMITNVTLSDSGVVTCVARNKSG 472
            ++ G     +L I +V L+D G   CVA+NKSG
Sbjct: 4256 DQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSG 4288



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 89/387 (22%), Positives = 155/387 (40%), Gaps = 32/387 (8%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            +   P F + M  + V E   A FE R+   G PKL+VEW +    IE S R T   D  
Sbjct: 1185 VLSRPEFKIKMSPVEVTEGSEAAFEVRV--EGFPKLQVEWFKGMTKIEDSGRYTFTADKN 1242

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA-SLQLESQH---ESALQKIQ 1822
               + +  V  ED+G Y C A N  G+  + + L V+ +  + + E++    +S + K  
Sbjct: 1243 RYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTIDSEVNKEV 1302

Query: 1823 QLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF 1882
            +++ ++    R+ +   V       T      KLS+  +  Y+C+         R  W  
Sbjct: 1303 EIKVTTGEPIRDSINTDVRAIGDSHTCFIVRAKLSD--AGVYKCQATNAAGSASR-SW-- 1357

Query: 1883 NGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAI-----NNLGQAVSSIRLNVQ 1937
              KV QS  +           L    +    +    CK        ++      +++   
Sbjct: 1358 EVKVKQSAPKTTGEEPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKIREN 1417

Query: 1938 SKESIIRDSQHESALEKIQYLEDDSRYKRAVQDD------------SFVVEKPQFGKPIK 1985
            S+  ++ D +  S   +   L+D+  YK  + ++            + V  +P F + +K
Sbjct: 1418 SRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKLK 1477

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD--FGYVALDILYAY 2043
                 EG     E  L+ +  PT  VEW+ +   +  G RF  T +   G   L I    
Sbjct: 1478 AVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTN 1535

Query: 2044 AEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             ED GTY   A N +G+  + + ++V+
Sbjct: 1536 IEDAGTYKVVAYNNLGKVTSQALLRVN 1562



 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 65/248 (26%), Positives = 101/248 (40%), Gaps = 15/248 (6%)

Query: 625  IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
            +P      V  PP+F   LK V  + G        I  +G PT  IEW K+ + +    R
Sbjct: 4193 LPKSRPSVVASPPRFQEELKGVITVVGTTTKLSVPI--IGHPTPVIEWYKDDREVLEGGR 4250

Query: 685  FT----SIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQH 740
                     RF  +SL +  + + D G Y C A + +G   + A + V  +   +  S  
Sbjct: 4251 IRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVKV--KELDDEDSIQ 4308

Query: 741  PETLQYIQQLEDYSKYQHQESIEEQT----SQRPQFIRPLQDLGELQEGRNAHFEAQLTP 796
               +   +   D +       + + T     + P+FIR L+D   +QE   A F  ++  
Sbjct: 4309 EGAMSLPKSTSDEALRMEDIPVAQSTPLKRGEPPEFIRKLRD-QFIQEKETARFVCRVIG 4367

Query: 797  VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
              DPT   EW +  +PIT   R T + +    +L I     ED G Y   + N  G   +
Sbjct: 4368 RPDPT--YEWLRGDKPITDGGRYTIMSDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTT 4425

Query: 857  TASIRVAA 864
            TA + V A
Sbjct: 4426 TARLTVEA 4433



 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 79/336 (23%), Positives = 136/336 (40%), Gaps = 30/336 (8%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV- 129
            P  F Q+ +     QG  A+FE K+ G+P P ++W +    L    +Y   + +  G+V 
Sbjct: 3140 PEFFRQL-RRVEAVQGSTARFECKVSGHPEPQIAWLKDGKELA-IPRYIKPFYD--GEVC 3195

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEA-------ICSVYIQPEGXXXXXXXXXXXXXYRHV 182
             L   +  P DEG+YTC A N+ GEA       +    + PE                  
Sbjct: 3196 KLTFYETQPEDEGDYTCVASNEAGEASSHASLVLSKPLVMPEFKERLKNIKVVEGDEAQF 3255

Query: 183  SETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL-LREVSFRESIT 241
            S  V+    G      E  +  +K+       H+       +   Y L + +V+  +  T
Sbjct: 3256 SVRVK----GEPEPKVEWFKTGKKIK-----SHARFSSKAGEKHTYTLTISDVAMEDFGT 3306

Query: 242  KRYVGESD---VQISTEIDRSLGPVSPPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPR 296
             + V  +D   VQ S  +D     V PP+I+         L EG D +  V ++GNP P 
Sbjct: 3307 YKCVASNDAGKVQCSGRLDVKERMV-PPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPD 3365

Query: 297  VTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
            + W+K+G  +  S    + +  +  +L +      D+G    +A NP G    S  + +E
Sbjct: 3366 LQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIE 3425

Query: 357  S--PTESYVQDQRSQYITDTQQRETEERIEISEKAL 390
            S  P   ++     Q + + +    E R+  + + +
Sbjct: 3426 SKKPAPLFIAPLHDQEVVEGETIRLECRVRATPRPM 3461



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 79/339 (23%), Positives = 135/339 (39%), Gaps = 40/339 (11%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            VEW K+ R  +    +  F       L I      D+G+Y C+A N  G  T +  + + 
Sbjct: 3658 VEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVVN 3717

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062
             +K ++     P G  K                       P FL  ++   +IVEG +A 
Sbjct: 3718 EQKVVMRRQPIPPGAVK-----------------------PSFLQRMQDL-EIVEGSAAR 3753

Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANRIQ-TYHDFGYVALDIASVRAEDSGVYTVVAR 1121
               RV+   +    ++WY + + I    R++  + + G   L I      D G Y  V  
Sbjct: 3754 LCVRVQGVPE--PEIDWYKDNRVIREGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVS 3811

Query: 1122 NAAGEAQLSASMTVETR---SSIDTSSIHRGLYEKTRH------IEESKFVEPMYQIEEI 1172
            NAAG+AQ SA + +ET    S +  + +     ++ R        +++   E      + 
Sbjct: 3812 NAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEARESTIELISDDTSDEEKTEGAPKE 3871

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY-YD 1231
              + P F   L N   V EG       R+  +    ++VEW+ + R ++      T+ +D
Sbjct: 3872 EGAPPEFTLVLRN-REVKEGGVTKFASRV--ISKAPIKVEWYKDDRLISSDWPRHTFEHD 3928

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
                A++I +   AD G YT    N  G+  + A + V+
Sbjct: 3929 EDLYAMNISNVKVADGGPYTFVVSNKYGTVESKAYLNVL 3967



 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 146/579 (25%), Positives = 220/579 (37%), Gaps = 93/579 (16%)

Query: 1809 QLESQHESALQKIQQLEDSSRYQ---------RREDVEVAVNQAPRFITQLNGPTK---L 1856
            + + QH + + K  Q+ED   Y+          R   ++ V +A   I   + P +   +
Sbjct: 3480 EFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKEA-LIIPHFDHPIQDLDV 3538

Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND--FGFAALDILTVYGEDS 1914
             EG  A +   +E    P  +VEW    + L++G R     D       L I      DS
Sbjct: 3539 IEGDRAKFH--VEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDS 3596

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G+YTC A N  G+     RL V  KE ++  S          + E D+       D+   
Sbjct: 3597 GKYTCIARNKAGENTCHGRLAV--KEKMVTPS----------FAEGDA-------DEPCE 3637

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            V +   G PIK     +G P            PT  VEW+   R  ++    K   +   
Sbjct: 3638 VWE---GAPIKLIVQIKGKPA-----------PT--VEWFKEKRQAKRLKNVKLFTEGDK 3681

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094
              L I  A  ED+G Y C+ATN  G    T  V V           +EQ++         
Sbjct: 3682 HMLVIPKAEPEDSGNYRCQATNDAGTVTKTFKVVV-----------NEQKV--------V 3722

Query: 2095 ERPKPIEEEQPGQ-RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR 2153
             R +PI    PG  +P FL  +  LE + EG  A    RV+ + +P   IDW+ + + IR
Sbjct: 3723 MRRQPI---PPGAVKPSFLQRMQDLE-IVEGSAARLCVRVQGVPEPE--IDWYKDNRVIR 3776

Query: 2154 AGHRYR-TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGH------RN 2206
             G R      + G   L I      D G Y C  +N  G+A  +  L +  H       +
Sbjct: 3777 EGGRVEFEFEEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSD 3836

Query: 2207 IILD-TQHPNGLEKIRQLEAQGHSTRIEVE-EPKI--SPPRFVTELRGTTHVFEGKTAHF 2262
              LD        E   +L +   S   + E  PK   +PP F   LR    V EG    F
Sbjct: 3837 ADLDFAARKEARESTIELISDDTSDEEKTEGAPKEEGAPPEFTLVLR-NREVKEGGVTKF 3895

Query: 2263 ECQVEPVHDPNLRIEFYHNGKALQSA-ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAIN 2321
              +V  +    +++E+Y + + + S   R     D    +++I +    D G Y+    N
Sbjct: 3896 ASRV--ISKAPIKVEWYKDDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSN 3953

Query: 2322 ALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360
              G   S   + V  +     E   P    K++  E  E
Sbjct: 3954 KYGTVESKAYLNVLPEMEPEFEGISPRFSVKLKNQEVIE 3992



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 62/232 (26%), Positives = 99/232 (42%), Gaps = 29/232 (12%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDFGYVA 1769
            PV    +KD+ V   + A F  R+      +  V+W ++ V +    R +    D G  +
Sbjct: 983  PVIEEKLKDVTVMPGEEAEFSIRV----SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFS 1038

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829
            L +  V PED GTY C   NE G+  T + L +  K ++    + ++A            
Sbjct: 1039 LTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI--KEAIVAPEEVDAA------------ 1084

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
                E V +    AP+    L    +++EG+    EC +   P P   VEW  +   L++
Sbjct: 1085 ----ETVPIE-GSAPKITKPLES-VEVNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRT 1136

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQSK 1939
             +R +   D   A L       ED GEY C  IN  G+A     +++NV S+
Sbjct: 1137 SYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSR 1188



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 89/348 (25%), Positives = 138/348 (39%), Gaps = 48/348 (13%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            ++ EG+    E  +  T     ++EW  +G+T +  + I T +      L I G +  D 
Sbjct: 3441 EVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYTEFDGQHCTLVIKGAQIEDE 3498

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            G Y C A NK G+     +L    K     P F   IQ+++ + +G  A F   V     
Sbjct: 3499 GAYECIAKNKEGRGRSVAQLTV--KEALIIPHFDHPIQDLDVI-EGDRAKFHVEV--SGK 3553

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
            P  K+EW    Q +R+  R+    D       L I   +  DSG+Y C A NK GE+   
Sbjct: 3554 PAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSGKYTCIARNKAGEN--- 3610

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
                C+G+  V  + + P S A        +G   +        P K I QI+       
Sbjct: 3611 ---TCHGRLAVKEKMVTP-SFA--------EGDADEPCEVWEGAPIKLIVQIK------- 3651

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356
                           P   VEWF   ++       + F +    +L I     E+SG Y 
Sbjct: 3652 -------------GKPAPTVEWFKEKRQAKRLKNVKLFTEGDKHMLVIPKAEPEDSGNYR 3698

Query: 3357 CVATNKLGRDSTKANLKCTSKENLILDSQ-LPRG--MEGGLEKLQTLE 3401
            C ATN  G   TK      +++ +++  Q +P G      L+++Q LE
Sbjct: 3699 CQATNDAG-TVTKTFKVVVNEQKVVMRRQPIPPGAVKPSFLQRMQDLE 3745



 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 118/531 (22%), Positives = 206/531 (38%), Gaps = 64/531 (12%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRL--IPVSDATLKVEWYHNNKPLKSGSRFT---ETNNF 1632
            P   T LK V+  EG+    + ++   P  D    +EWY     +    RF    E    
Sbjct: 686  PEFRTKLKPVKAVEGEEVQLDVKVEGYPKPD----IEWYRGTTMIVESGRFKVMEEEEED 741

Query: 1633 GFVALDIMSCLPEDSGTYTCRAINALGEAVT-SGIAIVHSKKSIYLESQHEGALPRLN-- 1689
            G  +L I     +D+GT    A NA G+A + + + +   + +   E   EG +      
Sbjct: 742  GLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKEREFAPEFEGDEEGPIVVTEGN 801

Query: 1690 --QLEDTSKYQRHSAQDEVITQAPVFTMPMKDI--RVAENQAAHFEARLIPVGDPKLRVE 1745
               ++   K   ++  D      P++    +DI  R  E+  A   + L   G  K    
Sbjct: 802  EVSIQLRVKANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEAS 861

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDS--GTYTCRAINELGEAV-----TSS 1798
                        ++      G   + +  + P ++  G  T       G+       T  
Sbjct: 862  NRLGKASRSFDVKVQVKGPKGEAPIILSKLRPVETEEGEETKLKCTFTGKPAPTCEWTRD 921

Query: 1799 TLFVQSKASLQLESQHESALQKIQQ--LEDSSRYQR--REDVEVAVNQAPRFITQLN--- 1851
             + ++S   +Q+++  +S+   I++  L+D   Y+   + D+      A   + ++    
Sbjct: 922  GIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNEVEKGV 981

Query: 1852 GPT---KLSE-----GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY-RTSNDFGFA 1902
            GP    KL +     G+ A +  R+    +    V+W+ +  +L    R+     D G  
Sbjct: 982  GPVIEEKLKDVTVMPGEEAEFSIRVSGRAE----VDWFKDEVMLNDEGRFIMEGGDNGRF 1037

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
            +L I  V  ED G Y C   N  G+  +  +L +  KE+I+   + ++A E +  +E  +
Sbjct: 1038 SLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI--KEAIVAPEEVDAA-ETVP-IEGSA 1093

Query: 1963 RYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ 2022
                           P+  KP+++ EV EG    LE  ++    PT  VEW  +   ++ 
Sbjct: 1094 ---------------PKITKPLESVEVNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRT 1136

Query: 2023 GHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
             +R K   D     L    A  ED G Y C   N  G+A TT  VKV+  S
Sbjct: 1137 SYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLS 1187



 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 54/227 (23%), Positives = 105/227 (46%), Gaps = 38/227 (16%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            + VEE +++ P+F+ ++ G   + +G   +++  +E    P   IE+YHN + + + +R 
Sbjct: 2148 LHVEE-ELTIPQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRV 2204

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
             ++F     ++ + +   +D+G Y  KA+N  G  +   ++ V  K        RPEG E
Sbjct: 2205 QLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK--------RPEGTE 2256

Query: 2352 KIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVE 2411
                                    P     L++++ ++EG+ A  +   +  G PT  +E
Sbjct: 2257 ------------------------PNIVSGLKSVE-VKEGEQAELE--FVVSGTPTPTLE 2289

Query: 2412 WFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            W+R+   +++S R+  T + G   + I+    ED G Y C+  N LG
Sbjct: 2290 WYRDGLRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQVRNDLG 2336



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 67/297 (22%), Positives = 128/297 (43%), Gaps = 32/297 (10%)

Query: 2944 KIEWYFNGKVLEQGSRFKLTS-DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVY 3002
            +++W+ +  +L    RF +   D G  +L + DV   D G Y C  +N+ G+  T + + 
Sbjct: 1011 EVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKL- 1069

Query: 3003 CTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISE 3062
            C  K+ ++     P+  +  E +  +E               G  P+ T   +  V+++E
Sbjct: 1070 CI-KEAIVA----PEEVDAAETVP-IE---------------GSAPKITKPLES-VEVNE 1107

Query: 3063 GQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYS 3122
            G+   ++   + +G  S  +EW  +   +  S+R++      +  L     +  D G Y 
Sbjct: 1108 GE--DFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYK 1165

Query: 3123 CRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMK 3182
            C   N+ G+A  + +++    S+   P F   +  +E + +G  A FE  V     P ++
Sbjct: 1166 CTVINEHGKASTTGEVKVNVLSR---PEFKIKMSPVE-VTEGSEAAFEVRVEGF--PKLQ 1219

Query: 3183 IEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
            +EW+     +  S R    +D     + IA     D+G Y C A N  G+  +RA +
Sbjct: 1220 VEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADL 1276



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 96/393 (24%), Positives = 150/393 (38%), Gaps = 75/393 (19%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQ-APRFIT-QLNGPTKLSEGQSAHYECRIEP 1870
            Q ++ + K   +  + +   R D+EV   Q AP F T +  GP  + EG     +  +  
Sbjct: 2418 QEDAGMYKCIAVNKAGKSTCRADLEVNERQFAPEFETGEERGPIVVPEGGETTLKVTLRA 2477

Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
             P P  +V WY +GK      R    +      L I     EDSG Y C+A N LG A  
Sbjct: 2478 NPKP--QVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADK 2535

Query: 1931 SIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVT 1990
            S  + V+  +      +  + L+++Q ++        ++ ++  +E    GKP       
Sbjct: 2536 SFTIRVEVPKP---TGEEPTILQRLQPVD-------TIEGEAIKMECRVSGKP------- 2578

Query: 1991 EGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTY 2050
                           +PT  + W  +G      +R KT +D     L I      D G Y
Sbjct: 2579 ---------------EPT--ITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIY 2621

Query: 2051 MCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPV 2110
             C A N+ G A +++ + V                     LE+  RP+ +E+ Q     V
Sbjct: 2622 RCNAKNSSGSAHSSAELTV---------------------LEREARPRILEKLQDVDSSV 2660

Query: 2111 FLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDFGYVAL 2169
                         G+RA F+ RV     P   + W+   ++I   GH        GY +L
Sbjct: 2661 -------------GERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSL 2705

Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
             I Y   ED G Y     N  GE  +T  L++A
Sbjct: 2706 TIEYIDYEDEGAYKAVVINDSGEVSSTAVLRLA 2738



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 16/134 (11%)

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
            +D G+Y C A N AG   C AE +V  PA  D+      AA     ++          G 
Sbjct: 5938 EDEGEYTCRASNPAGSCSCTAELIVDAPAKVDQ------AATPGSGVV----------GG 5981

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
             I  +C I G P+PT  W++GD+ +K      +  T D  +L I      DEG+Y+ V  
Sbjct: 5982 KITLTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVK 6041

Query: 4699 NSAGRVTVAAKLKV 4712
            N  G  +   KL V
Sbjct: 6042 NDGGEDSCVVKLTV 6055



 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 80/345 (23%), Positives = 132/345 (38%), Gaps = 48/345 (13%)

Query: 253  STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
            ST  +  +  +S P+   K    ++ EG++A F+V++ G P+ +V WFK   ++ +S ++
Sbjct: 1176 STTGEVKVNVLSRPEFKIKMSPVEVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRY 1235

Query: 313  EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYIT 372
                           T  +D   YT++  N        GY  V + T      +      
Sbjct: 1236 ---------------TFTADKNRYTMVIANVT-LEDAGGYRCVATNTAGKTTSRAD---- 1275

Query: 373  DTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
                      + + E+  AP+F    + RD T       D  V      +VT       I
Sbjct: 1276 ----------LTVKEREFAPEF----ETRDDT------IDSEVNKEVEIKVT---TGEPI 1312

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE---KEQVV 489
            RD  N  +      +H   I    LSD+GV  C A N +G  +    + V +   K    
Sbjct: 1313 RDSINTDVRAI-GDSHTCFIVRAKLSDAGVYKCQATNAAGSASRSWEVKVKQSAPKTTGE 1371

Query: 490  APKFVERFSTLNVREGEPVVLNARAVGT-PTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
             P  + +     + EG    L  +     P P I W +DGV I  N  +++  DG   +L
Sbjct: 1372 EPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKIRENSRIKMVFDGETCSL 1431

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRL 593
             I  A   D   Y+ T  N  G+ ++  R+           Q++L
Sbjct: 1432 TIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKL 1476



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 77/317 (24%), Positives = 125/317 (39%), Gaps = 29/317 (9%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V+  EG+    + +   TG  +   EW  +G  I +S  ++         L I  T   D
Sbjct: 894  VETEEGEETKLKCTF--TGKPAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDD 951

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             G Y C   N  G    S ++   +  KG  P     ++++  +  G+ A F   V    
Sbjct: 952  EGLYKCTIKNDLGTVSTSAEVLVNEVEKGVGPVIEEKLKDVT-VMPGEEAEFSIRV---- 1006

Query: 3178 DPDMKIEWYHNGQPMRHSTR-IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
                +++W+ +   +    R I    D G   L I+  +  D G Y C  +N+ G+  TR
Sbjct: 1007 SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTR 1066

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            A + C  +  V  E +                A +  P   SA  PK IT+  +  ++ E
Sbjct: 1067 AKL-CIKEAIVAPEEVD---------------AAETVPIEGSA--PK-ITKPLESVEVNE 1107

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYE 3356
            G+   F+   V    P   VEW  +  KL   +R +   D  +  L       E+ GEY+
Sbjct: 1108 GED--FDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYK 1165

Query: 3357 CVATNKLGRDSTKANLK 3373
            C   N+ G+ ST   +K
Sbjct: 1166 CTVINEHGKASTTGEVK 1182



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 122/519 (23%), Positives = 190/519 (36%), Gaps = 61/519 (11%)

Query: 3413 EEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRF-RT 3471
            E EKG  PV    L ++  +  GE A F  R++       +V+W+ +   L    RF   
Sbjct: 976  EVEKGVGPVIEEKLKDV-TVMPGEEAEFSIRVSG----RAEVDWFKDEVMLNDEGRFIME 1030

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGT 3531
              D G   L IS   PED G Y C  +N  G+  T A + ++                  
Sbjct: 1031 GGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIK------------------ 1072

Query: 3532 IDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV 3591
             + I A E     VD        G+ P+ T     + ++E      EC  +     S  V
Sbjct: 1073 -EAIVAPE----EVDAAETVPIEGSAPKITKPLESVEVNEGEDFDLEC--VVSGSPSPTV 1125

Query: 3592 EWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA--TVSCKLQV 3649
            EW  +   L T  R+K   D     L        D G Y C   N HG+A  T   K+ V
Sbjct: 1126 EWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNV 1185

Query: 3650 KGRQ--GIILEP-----QLPSHFKSGTESIQKLE----ETLHKREEITIEDEKPNPPRFT 3698
              R    I + P        + F+   E   KL+    + + K E+        +  R+T
Sbjct: 1186 LSRPEFKIKMSPVEVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYTFTADKNRYT 1245

Query: 3699 VEIKDNIDVPEGGPVHFDC-RVEPVGDPTMRIDWFHNGRPFAT--GSRVHTLNDFGFIAL 3755
            + I  N+ + + G   + C      G  T R D     R FA    +R  T++      +
Sbjct: 1246 MVIA-NVTLEDAG--GYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTIDSEVNKEV 1302

Query: 3756 DIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGR 3815
            +I         +         G + T   +        V + Q     +G   +  E   
Sbjct: 1303 EIKVTTGEPIRDSINTDVRAIGDSHTCFIVRAKLSDAGVYKCQATNA-AGSASRSWEVKV 1361

Query: 3816 ISDAPK---EEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
               APK   EEPI+      I ++++  ++E       C+V   + P+  I+W R+G  +
Sbjct: 1362 KQSAPKTTGEEPII------IRKLQAQEIDEGSTANLVCKVTAAK-PEPSIKWTRDGVKI 1414

Query: 3873 PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                R + V+D    SL I     +D G Y     N++G
Sbjct: 1415 RENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYG 1453



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 65/242 (26%), Positives = 101/242 (41%), Gaps = 44/242 (18%)

Query: 3679 LHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF 3738
            LH  EE+TI       P+F  ++   +++ +G   ++D  +E  G P   I+W+HN R  
Sbjct: 2148 LHVEEELTI-------PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLI 2198

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
               SRV          + +  +   D+G Y C+       A  TA  T S + +I ++ +
Sbjct: 2199 YATSRVQLSFISSKATIALYNVTLDDSGLYRCK-------AVNTAG-TGSKQFNINVQPK 2250

Query: 3799 LPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKED 3858
             P+G                         T P  ++ +KS  V+E E    E  V     
Sbjct: 2251 RPEG-------------------------TEPNIVSGLKSVEVKEGEQAELEFVVSGTPT 2285

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKAT 3918
            P L  EWYR+G  +    R R+  + G   L I   +AED G Y C+  ND G   T A 
Sbjct: 2286 PTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAH 2343

Query: 3919 IS 3920
            ++
Sbjct: 2344 LN 2345



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 53/194 (27%), Positives = 81/194 (41%), Gaps = 6/194 (3%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F        ++ EG     +A  +  G+    I W+ +      S ++         
Sbjct: 3039 PPGFEGPDHGSYELQEGDTITLDA--VVKGNPYPEIRWYKDEFLAMESKKLMLSVRDRKN 3096

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQ 3165
             L +      DSG Y C   NK G A  S  ++    KSKG  P F   ++ +E ++ G 
Sbjct: 3097 SLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKSKGIIPEFFRQLRRVEAVQ-GS 3155

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A FEC V     P+ +I W  +G+ +     IK   D     L    TQ  D G+Y C 
Sbjct: 3156 TARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDEGDYTCV 3213

Query: 3226 AYNKYGEDFTRATI 3239
            A N+ GE  + A++
Sbjct: 3214 ASNEAGEASSHASL 3227



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 56/221 (25%), Positives = 94/221 (42%), Gaps = 12/221 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            PEF    +  +D + G       S+  +G     I W+ NGK +  S ++    +     
Sbjct: 201  PEFIDEERGPIDATTGDEVTLTCSV--SGKPKPSITWYKNGKLLTDSLKLDIRSSGERNW 258

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            + +L  K  D+  Y C A NK G+A  +  ++ V   KG  P FT  + ++  + +G+ +
Sbjct: 259  VTMLSAKPEDTALYKCEAENKLGKASRAFDVK-VKAPKGDAPSFTIDLTHVRAI-EGEES 316

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C V     P   IEW     P+  S R++T  +     L I  T+  D+G Y   A 
Sbjct: 317  KLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVAR 374

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQG 3268
            N  G   + A +       V   S +P+    +R++ +L G
Sbjct: 375  NDSGTAHSIAELQ------VQERSTKPEIEDSLRDVSALPG 409



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 76/280 (27%), Positives = 116/280 (41%), Gaps = 44/280 (15%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F K  ++  V EG  V L A +T    P   +EW  +G+ V++ +   T        L
Sbjct: 492  PRFEKMKESFTVVEGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVL 549

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             I  +  +D+G Y C A N               KSG    T D      +Q     ++P
Sbjct: 550  TIEESSRDDSGLYRCTARN---------------KSG----TADMTFQLDVQP----KKP 586

Query: 2098 KPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR 2157
            K       G  P  ++ L  +E   EGD A   C +     P  TI+W  NG +++   R
Sbjct: 587  K-------GTAPEIVSELRPVE-ATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRR 636

Query: 2158 YRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGL 2217
             +     G V L I  T A+D G Y C   N+LG A +   LKV       +    P   
Sbjct: 637  TKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV-------IAFARPEFR 689

Query: 2218 EKIRQLEA-QGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256
             K++ ++A +G   +++V+      P  +   RGTT + E
Sbjct: 690  TKLKPVKAVEGEEVQLDVKVEGYPKPD-IEWYRGTTMIVE 728



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 48/189 (25%), Positives = 81/189 (42%), Gaps = 11/189 (5%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            ++ EG     E ++  +G  +  IEW+ +G    A+ R+ T +   +  +     +  D 
Sbjct: 1678 EVKEGGTVTLECTV--SGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDD 1735

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            G Y C ATN  G A+ S +L     S   KP F   ++ +E + +G  A F+  +     
Sbjct: 1736 GEYKCVATNPLGSAQSSARLTVTVPS---KPEFKQKLRPLE-VVEGSEAKFDVRIKSYPK 1791

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDF---GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
            P+  +EWY     +  S R +    +       L I  T   D+  Y C A+N+ G+   
Sbjct: 1792 PE--VEWYRGTTKITDSLRHQITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTC 1849

Query: 3236 RATINCYGK 3244
            RA +    K
Sbjct: 1850 RADLTVIEK 1858



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 5/115 (4%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P+F R L  +E V+G+    EC++   G    ++ W  +GK +      +P Y+ +   L
Sbjct: 3140 PEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKL 3197

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
                  PED G YTC A+N+ GEA +  +L  +  K L++  +    L+ I+ +E
Sbjct: 3198 TFYETQPEDEGDYTCVASNEAGEASSHASL--VLSKPLVM-PEFKERLKNIKVVE 3249



 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 45/150 (30%), Positives = 71/150 (47%), Gaps = 9/150 (6%)

Query: 3110 ILGTKTTDSGTYSCRATNKWGQA----EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            I+  K +D+G Y C+ATN  G A    E+ VK +   K+ G++P     +Q  E + +G 
Sbjct: 1331 IVRAKLSDAGVYKCQATNAAGSASRSWEVKVK-QSAPKTTGEEPIIIRKLQAQE-IDEGS 1388

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A+  C V     P+  I+W  +G  +R ++RIK V D     L I      D G Y   
Sbjct: 1389 TANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVT 1447

Query: 3226 AYNKYG--EDFTRATINCYGKGGVYLESLQ 3253
              N+YG      R  +N  G   ++ + L+
Sbjct: 1448 LTNEYGTASSTCRVLVNEVGSRPIFQQKLK 1477



 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 36/97 (37%), Positives = 53/97 (54%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            +  AP   THL S + + EG  V LE  V  +  PN  IEW+K+G+  T   R+ +TFD 
Sbjct: 1664 IGNAPDIITHLISKE-VKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMTTFDG 1720

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             + +++    +  D G Y C ATN LG A S+A + +
Sbjct: 1721 SVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757



 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 54/186 (29%), Positives = 77/186 (41%), Gaps = 8/186 (4%)

Query: 3047 PPEFTT-VFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            PPE +T V +    ++EG       S+  TG+    ++W+ +G  I  S  I        
Sbjct: 3332 PPEISTDVLEGPALLNEGDDLRLVVSV--TGNPIPDLQWYKDGVLIRRSTHISLSSIGSR 3389

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
              L I+G    D+G   C A N  G A  S     V +SK   P F   + + E + +G+
Sbjct: 3390 YSLAIMGVVPEDTGVIKCVAMNPAGSA--SKSFTVVIESKKPAPLFIAPLHDQE-VVEGE 3446

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +   EC V     P   +EW  +G+  +    I T  D     L I   Q  D G Y C 
Sbjct: 3447 TIRLECRVRATPRP--MVEWKKDGRTFKEDYHIYTEFDGQHCTLVIKGAQIEDEGAYECI 3504

Query: 3226 AYNKYG 3231
            A NK G
Sbjct: 3505 AKNKEG 3510



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 64/232 (27%), Positives = 101/232 (43%), Gaps = 32/232 (13%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRY-RTFHDFGIV 3340
            P    +++DVT ++ G+ A F  R+        +V+WF +   L    R+     D G  
Sbjct: 983  PVIEEKLKDVT-VMPGEEAEFSIRV----SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRF 1037

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400
             L I     E+ G Y+C+  N+ G+ +T+A L C  KE ++             E++   
Sbjct: 1038 SLTISDVRPEDKGTYKCLVFNESGKVTTRAKL-CI-KEAIVAP-----------EEVDAA 1084

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
            E   +          +G AP  T PL ++E + EGE+  F+     +  P+  VEW  + 
Sbjct: 1085 ETVPI----------EGSAPKITKPLESVE-VNEGED--FDLECVVSGSPSPTVEWTKDL 1131

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
              L+   R +   D     L      PED GEY C   N +G+A TT  +KV
Sbjct: 1132 VKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 36/94 (38%), Positives = 51/94 (54%), Gaps = 3/94 (3%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            +PEFK  +   + + EG  A FE R+E  G   L+VEW K    +E S R T   +    
Sbjct: 1188 RPEFKIKMSP-VEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             + I +VT+ DAG Y C A N  G+ T+ A+LT+
Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 82/324 (25%), Positives = 129/324 (39%), Gaps = 52/324 (16%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G  P FT     +  I EG+ +     +  TG  +  IEW      +  S R+RT +   
Sbjct: 296  GDAPSFTIDLTHVRAI-EGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDFEKN 352

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +  L I  T+  D+GTY   A N  G A    +L+  ++S   KP     ++++  L  G
Sbjct: 353  VATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERST--KPEIEDSLRDVSALP-G 409

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR--IKTVSD--FGFVVLDIAYTQNHDSG 3220
            +   F+  +     P  K+EW      +    R  I   SD  F  ++ D+  T   D+G
Sbjct: 410  ERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEET---DAG 464

Query: 3221 EYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAE 3280
             Y C A N                     E+ + +S+A++   E L G            
Sbjct: 465  RYKCVATN---------------------EAGEAESMAQLTVNEELIG------------ 491

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIV 3340
             P+F    +  T +VEG+S    AR+     P+  +EW  +GK +   +   T       
Sbjct: 492  -PRFEKMKESFT-VVEGESVELVARVTGKPAPE--IEWTKDGKTVRKTNNVDTKERDDQA 547

Query: 3341 ILDILYCYEENSGEYECVATNKLG 3364
            +L I     ++SG Y C A NK G
Sbjct: 548  VLTIEESSRDDSGLYRCTARNKSG 571



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 73/282 (25%), Positives = 114/282 (40%), Gaps = 39/282 (13%)

Query: 994  TTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGP----- 1048
            TT  + T++ K+  + +     GL K     D    S  T  EV + +  + +GP     
Sbjct: 935  TTEDSSTLIIKETTLDDE----GLYKCTIKNDLGTVS--TSAEVLVNEVEKGVGPVIEEK 988

Query: 1049 LKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR-IQTYHDFGYVALDIAS 1107
            LK    ++ G+ A F  RV  +++    V+W+ +   +    R I    D G  +L I+ 
Sbjct: 989  LKDVT-VMPGEEAEFSIRVSGRAE----VDWFKDEVMLNDEGRFIMEGGDNGRFSLTISD 1043

Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMY 1167
            VR ED G Y  +  N +G+    A + ++               E     EE    E + 
Sbjct: 1044 VRPEDKGTYKCLVFNESGKVTTRAKLCIK---------------EAIVAPEEVDAAETV- 1087

Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
                I  S P   +PL +   V+EG++  LEC +   G P+  VEW  +   +    R K
Sbjct: 1088 ---PIEGSAPKITKPLESVE-VNEGEDFDLECVVS--GSPSPTVEWTKDLVKLRTSYRLK 1141

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
               D     L    A   D GEY    +N  G A T+  V+V
Sbjct: 1142 EKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 84/355 (23%), Positives = 136/355 (38%), Gaps = 63/355 (17%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G+ P+ L+ L  +E  +EG+    +C       P  T +W  +G +IR+           
Sbjct: 882  GEAPIILSKLRPVET-EEGEETKLKCTFT--GKPAPTCEWTRDGIRIRSSRM-------- 930

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225
             V +D      EDS T + K T    E +  CT+K                      L  
Sbjct: 931  -VQIDT----TEDSSTLIIKETTLDDEGLYKCTIK--------------------NDLGT 965

Query: 2226 QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKAL 2285
               S  + V E +      + E      V  G+ A F  +V         ++++ +   L
Sbjct: 966  VSTSAEVLVNEVEKGVGPVIEEKLKDVTVMPGEEAEFSIRVSG----RAEVDWFKDEVML 1021

Query: 2286 QSAARFHITF-DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344
                RF +   D G  SL I    PED G Y     N  G  T+   + +  K +I++  
Sbjct: 1022 NDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI--KEAIVA-- 1077

Query: 2345 QRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVG 2404
              PE      E+++AE         P+    P  T+PL++++ + EG+   FD   +  G
Sbjct: 1078 --PE------EVDAAETV-------PIEGSAPKITKPLESVE-VNEGED--FDLECVVSG 1119

Query: 2405 DPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             P+  VEW ++   +  S R+ +  D     +     R ED G Y C   N  G+
Sbjct: 1120 SPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGK 1174



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 3/98 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            + P     L+  D  +EG+ + +E +V  + +P   I W K+G+   T  R+K+ FD  +
Sbjct: 2549 EEPTILQRLQPVDT-IEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDV 2605

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             TL+I  ++  D GIY C A N  G A S+A + + +R
Sbjct: 2606 CTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLER 2643



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 50/203 (24%), Positives = 82/203 (40%), Gaps = 20/203 (9%)

Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGAR-LKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            EA+   R     +++WFK+ V L    R +    D G  +L+I+ +R +D G Y C   N
Sbjct: 999  EAEFSIRVSGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFN 1058

Query: 2722 LLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLN 2781
              G+  + A + I++        + P+ +D    +                       L 
Sbjct: 1059 ESGKVTTRAKLCIKEA------IVAPEEVDAAETVPIEGSAPKIT-----------KPLE 1101

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++   EG++   EC V  S  PT  +EW  +   L +  R K   D +   L       E
Sbjct: 1102 SVEVNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPE 1159

Query: 2842 DSGIYTCKATNSKGSATTSGSLR 2864
            D G Y C   N  G A+T+G ++
Sbjct: 1160 DIGEYKCTVINEHGKASTTGEVK 1182



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 64/243 (26%), Positives = 92/243 (37%), Gaps = 28/243 (11%)

Query: 3683 EEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742
            E +  E EK   P    ++KD + V  G    F  RV    +    +DWF +        
Sbjct: 971  EVLVNEVEKGVGPVIEEKLKD-VTVMPGEEAEFSIRVSGRAE----VDWFKDEVMLNDEG 1025

Query: 3743 R-VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801
            R +    D G  +L I  +   D G Y C   N+ G  TT AK+ C  K  IV   ++  
Sbjct: 1026 RFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKL-C-IKEAIVAPEEV-- 1081

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861
                            DA +  PI  + PK    ++S  V E E    EC V     P  
Sbjct: 1082 ----------------DAAETVPIEGSAPKITKPLESVEVNEGEDFDLECVVSGSPSPT- 1124

Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISC 3921
             +EW ++   L + +R +   D     L       ED GEY C  +N+ G+  T   +  
Sbjct: 1125 -VEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183

Query: 3922 KKL 3924
              L
Sbjct: 1184 NVL 1186



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 36/97 (37%), Positives = 47/97 (48%), Gaps = 3/97 (3%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            +  AP  IT L    ++ EG +   EC +   P PN  +EWY +G    +  R  T+ D 
Sbjct: 1664 IGNAPDIITHLISK-EVKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMTTFDG 1720

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
              A++      G D GEY C A N LG A SS RL V
Sbjct: 1721 SVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 2/93 (2%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            +P     +K+ EV EG    LE  ++    PT+  EWY +G  V++  R ++T + G   
Sbjct: 2256 EPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIAR 2313

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L I   +AED GTY C+  N +G   T++ + +
Sbjct: 2314 LVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 80/285 (28%), Positives = 111/285 (38%), Gaps = 49/285 (17%)

Query: 1974 VVEKPQF-GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
            V+  P+F  K     E TEG    LE T+     P   +EW+   R + +  R       
Sbjct: 1564 VLTVPEFMDKAEGPIEKTEGDD--LELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRD 1621

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092
                + +     +D+G Y C A N  G +  T +             LD Q+ K I    
Sbjct: 1622 NKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFN-------------LDVQKKKVI---- 1664

Query: 2093 KYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
                         G  P  +T L S E +KEG     EC V     P   I+W+ +G + 
Sbjct: 1665 -------------GNAPDIITHLISKE-VKEGGTVTLECTVS--GKPAPNIEWYKDGLRF 1708

Query: 2153 RAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKATNKLGEAVNTCTLKVAGHRNIILD 2210
             A  R  TT D G VA  + +T A+  D G Y C ATN LG A ++  L V         
Sbjct: 1709 TATRRVMTTFD-GSVA-SVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVT-------V 1759

Query: 2211 TQHPNGLEKIRQLE-AQGHSTRIEVEEPKISPPRFVTELRGTTHV 2254
               P   +K+R LE  +G   + +V       P  V   RGTT +
Sbjct: 1760 PSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKPE-VEWYRGTTKI 1803



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 7/195 (3%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G+ VL I  T+  D+G Y C A N  G  E++ K     + +   P+F   +  +  L  
Sbjct: 2114 GLFVLTIRNTRPEDAGEYQCIAVN--GAGEVTSKGYLHVEEELTIPQFIGDVPGVVELVQ 2171

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G +  ++ ++     P  +IEWYHN + +  ++R++         + +      DSG Y 
Sbjct: 2172 GDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYR 2229

Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPK 3283
            C+A N  G    +  IN   K     E  +P+ ++ ++ +E  +G Q +     S  P  
Sbjct: 2230 CKAVNTAGTGSKQFNINVQPKRP---EGTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTP 2286

Query: 3284 FITQIQDVTKLVEGQ 3298
             +   +D  ++ E +
Sbjct: 2287 TLEWYRDGLRVKESR 2301



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 35/105 (33%), Positives = 52/105 (49%), Gaps = 3/105 (2%)

Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            ++ + +  +P  +Q L  P    EG+ I +ECR+    +PT  + W  +G      +R K
Sbjct: 2542 EVPKPTGEEPTILQRLQ-PVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIK 2598

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            TY+D     L I      D G Y   A N  GSAH+SA + V+ER
Sbjct: 2599 TYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLER 2643



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 47/183 (25%), Positives = 73/183 (39%), Gaps = 8/183 (4%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            VD  EG+    E  +  +G     I W  +G      +RI+T +   +  L I   K  D
Sbjct: 2560 VDTIEGEAIKMECRV--SGKPEPTITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGD 2617

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             G Y C A N  G A  S +L  +++    +PR    +Q+++    G+ A F+  V    
Sbjct: 2618 EGIYRCNAKNSSGSAHSSAELTVLERE--ARPRILEKLQDVDS-SVGERAMFKIRV--SG 2672

Query: 3178 DPDMKIEWYHNGQPMRHSTR-IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
             P   ++WY   + +      I      G+  L I Y    D G Y     N  GE  + 
Sbjct: 2673 SPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLTIEYIDYEDEGAYKAVVINDSGEVSST 2732

Query: 3237 ATI 3239
            A +
Sbjct: 2733 AVL 2735



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 63/221 (28%), Positives = 91/221 (41%), Gaps = 40/221 (18%)

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPK 2098
            I+ A   D G Y C+ATNA G A  +  VKV                       K   PK
Sbjct: 1331 IVRAKLSDAGVYKCQATNAAGSASRSWEVKV-----------------------KQSAPK 1367

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158
               EE     P+ +  L + E + EG  A+  C+V     P  +I W  +G KIR   R 
Sbjct: 1368 TTGEE-----PIIIRKLQAQE-IDEGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRI 1420

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV--AGHRNIILDTQHPNG 2216
            +   D    +L I     +D G Y    TN+ G A +TC + V   G R I         
Sbjct: 1421 KMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIF-----QQK 1475

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEG 2257
            L+ +  +E  G STR EV+   +  P  V   + ++ +++G
Sbjct: 1476 LKAVSTIE--GESTRFEVKLSAMPRPT-VEWFKSSSQIYDG 1513



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 7/182 (3%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            + EG   +  A++   G  S  + W+ +G+ +  S +  T        L +   K  D+G
Sbjct: 1875 VKEGDDLNISATI--AGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932

Query: 3120 TYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            +Y C A NK G    +  ++ +  + +GQ P FT+ +  +E + +G        +     
Sbjct: 1933 SYKCEANNKLGTVTKTYNVKVMSTAPEGQAPSFTSEMSQVE-VDEGGEVKLYFLISGYPK 1991

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRA 3237
            P +K  W  +G P+    RI   S     V L I     +D G Y C   N++G   T  
Sbjct: 1992 PTVK--WTRDGIPVFEDYRISMDSSRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTV 2049

Query: 3238 TI 3239
             +
Sbjct: 2050 QV 2051



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 2/118 (1%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+FI  + G  +L +G +  Y+  +E    P   +EWY N +++ +  R + S     A 
Sbjct: 2157 PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
            + +  V  +DSG Y CKA+N  G       +NVQ K     +    S L+ ++  E +
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVEVKEGE 2272



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR--VKTINDFGFV 3615
            PEF    + + ++E   A FE R+         VEW+H    +L   R  ++++ + G+ 
Sbjct: 2352 PEFKEKLTKVEVTEGDRAKFEVRV--KGYPYPEVEWYHGSNRILDEDRFEIESVKETGYY 2409

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
             L +G V Q DAG+Y C A N+ G++T    L+V  RQ
Sbjct: 2410 SLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQ 2447



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 43/150 (28%), Positives = 70/150 (46%), Gaps = 9/150 (6%)

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
            ++ R E      ++P  L  L+  + I EG++   E RV  + + T+T  W  +G    +
Sbjct: 2537 FTIRVEVPKPTGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPTIT--WLKDGLVFLT 2593

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
             NRI+TY D     L I  V+  D G+Y   A+N++G A  SA +TV  R +        
Sbjct: 2594 DNRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLEREA------RP 2647

Query: 1149 GLYEKTRHIEESKFVEPMYQIEEISKSKPV 1178
             + EK + ++ S     M++I       PV
Sbjct: 2648 RILEKLQDVDSSVGERAMFKIRVSGSPMPV 2677



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 56/209 (26%), Positives = 81/209 (38%), Gaps = 13/209 (6%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHD----FGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +G P+   EWY +  E+  G R R   D    F  V+L I  V   D G Y C A N++G
Sbjct: 4229 IGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFTIVSLTIRDVRLTDEGRYKCVAKNKSG 4288

Query: 2591 XXXXXXXXXXXXXX---XIIDQAMR-PESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTT 2646
                              I + AM  P+S     L+   +       +  G  + P F  
Sbjct: 4289 TDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDIPVAQSTPLKRG--EPPEFIR 4346

Query: 2647 HLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINS 2706
             L+    + E +      +V  R DP    EW +    +T G R     D    TL I  
Sbjct: 4347 KLRD-QFIQEKETARFVCRVIGRPDPTY--EWLRGDKPITDGGRYTIMSDDEGQTLEITD 4403

Query: 2707 LRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
               +D G+Y C +TN  G   +TA + +E
Sbjct: 4404 CTVEDEGLYKCVSTNSSGTDTTTARLTVE 4432



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 5/125 (4%)

Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTM 1075
            G  K Q   D  R S      + +  +P F   L    ++ EG  A FE RV+       
Sbjct: 2325 GTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKV-EVTEGDRAKFEVRVKGYP--YP 2381

Query: 1076 TVEWYFNGKQITSANR--IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
             VEWY    +I   +R  I++  + GY +L +  V  ED+G+Y  +A N AG++   A +
Sbjct: 2382 EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441

Query: 1134 TVETR 1138
             V  R
Sbjct: 2442 EVNER 2446



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 94/403 (23%), Positives = 164/403 (40%), Gaps = 35/403 (8%)

Query: 3685 ITIEDEKPNPPRFTV-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            I +E  KP     T+ +    +D  EG  +  +CRV    +PT  I W  +G  F T +R
Sbjct: 2539 IRVEVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNR 2596

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK--RDIVLESQLPQ 3801
            + T  D     L I  +   D G Y C A N  GSA ++A++T   +  R  +LE +L  
Sbjct: 2597 IKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLEREARPRILE-KLQD 2655

Query: 3802 GMSGEKIKELERGRISDAP-------KEEPIVSTPPKFITQIK-----SHTVE----ESE 3845
              S    + + + R+S +P       + +  ++T   +I + +     S T+E    E E
Sbjct: 2656 VDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLTIEYIDYEDE 2715

Query: 3846 GVRFECRV-EPKEDPKLRIEWYRNGKLLPS--GHRYR--TVYDMGFVSLDILYVYAE--D 3898
            G      + +  E     +     G + PS  G  +   T Y+   + L   YV      
Sbjct: 2716 GAYKAVVINDSGEVSSTAVLRLAEGMIEPSFIGIEFEPITAYEGSDIDL-TFYVKGRPLP 2774

Query: 3899 SGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVY 3958
            + E++   V  F  D T+ T +  +   + L +   R     +A+ + +A + + + E+ 
Sbjct: 2775 TVEFLKDEVPVFKSDRTELTSNGNR-HTLYLSDLAVRDSATYKAVAKNKAGVARRSVEL- 2832

Query: 3959 LTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
            L +        +  P  V ++++   + E  + K  C++   G P   +EW+ +  PL  
Sbjct: 2833 LVKPKRGLKPGEAAPEIVQRLKA-CEVPEGSSFKLRCRV--TGTPTPTIEWYKSNMPLKP 2889

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
              R    +      +NF      D G Y+  A N  G   T A
Sbjct: 2890 NGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSA 2932



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 3/106 (2%)

Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
            +V+V V   P F  +++ P +++EG  A +E R+E +P   ++VEW+     ++   RY 
Sbjct: 1180 EVKVNVLSRPEFKIKMS-PVEVTEGSEAAFEVRVEGFP--KLQVEWFKGMTKIEDSGRYT 1236

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             + D     + I  V  ED+G Y C A N  G+  S   L V+ +E
Sbjct: 1237 FTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKERE 1282



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 34/85 (40%), Positives = 47/85 (55%), Gaps = 3/85 (3%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            RP F   +  ++ + EG  A F+ R+   G P L+VEWF+    IEDS R T T D    
Sbjct: 1188 RPEFKIKMSPVE-VTEGSEAAFEVRV--EGFPKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
            +M I++V  ED G Y C A+N  G+
Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGK 1269



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 41/167 (24%), Positives = 79/167 (47%), Gaps = 13/167 (7%)

Query: 1801 FVQSKASLQLESQ--HESALQKIQQLEDSSRYQRREDVEVAVNQA----PRFITQLNGPT 1854
            F+ SKA++ L +    +S L + + +  +    ++ ++ V   +     P  ++ L    
Sbjct: 2208 FISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKS-V 2266

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            ++ EG+ A  E  +   P P +  EWY +G  ++   R R++ + G A L I   + ED 
Sbjct: 2267 EVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDM 2324

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
            G Y C+  N+LG+  +S  LN+     +    + +  L K++  E D
Sbjct: 2325 GTYKCQVRNDLGRTSTSAHLNI----IVATRPEFKEKLTKVEVTEGD 2367



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 59/246 (23%), Positives = 100/246 (40%), Gaps = 13/246 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGM 3105
            PEF       V+++EG  A +E  +   G     +EW++    I  E    I +V   G 
Sbjct: 2352 PEFKEKLTK-VEVTEGDRAKFEVRV--KGYPYPEVEWYHGSNRILDEDRFEIESVKETGY 2408

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDG 3164
              L +      D+G Y C A NK G++     LE  ++     P F T  +     + +G
Sbjct: 2409 YSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQFA--PEFETGEERGPIVVPEG 2466

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                 + T+    +P  ++ WY +G+    + R+   S      L I   +  DSG Y C
Sbjct: 2467 GETTLKVTLRA--NPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKC 2524

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
             A NK G      TI             +P  L +++ +++++G   +     S +P   
Sbjct: 2525 EARNKLGFADKSFTIRVEVPKPT---GEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT 2581

Query: 3285 ITQIQD 3290
            IT ++D
Sbjct: 2582 ITWLKD 2587



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 54/188 (28%), Positives = 79/188 (42%), Gaps = 13/188 (6%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV- 3106
            PEF    K+I  + EG  A +   +   G+    +EWF  GK I++  R  +        
Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG---LKD 3163
             L I      D GTY C A+N  G+ + S +L+   K +   P  +T +  +EG   L +
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV--KERMVPPEISTDV--LEGPALLNE 3348

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G       +V     PD  ++WY +G  +R ST I   S      L I      D+G   
Sbjct: 3349 GDDLRLVVSVTGNPIPD--LQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIK 3406

Query: 3224 CRAYNKYG 3231
            C A N  G
Sbjct: 3407 CVAMNPAG 3414



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 66/261 (25%), Positives = 109/261 (41%), Gaps = 44/261 (16%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF---G 2033
            +P+F   +K  +  EG  V L+  +     P   +EWY     + +  RFK   +    G
Sbjct: 685  RPEFRTKLKPVKAVEGEEVQLDVKVEGYPKPD--IEWYRGTTMIVESGRFKVMEEEEEDG 742

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEK 2093
              +L I     +DTGT    ATNA G+A + +                        +LE 
Sbjct: 743  LYSLVISKLQLDDTGTIKVVATNASGKATSRA------------------------DLEV 778

Query: 2094 YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR 2153
             ER    E E   + P+ +T         EG+    + RV+   +P+  +DWF +G+ I 
Sbjct: 779  KEREFAPEFEGDEEGPIVVT---------EGNEVSIQLRVKA--NPNADVDWFKDGRPIY 827

Query: 2154 AGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQH 2213
               +           L I  +  ED+G Y C+A+N+LG+A  +  +KV          + 
Sbjct: 828  ESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQVKGP---KGEA 884

Query: 2214 PNGLEKIRQLEA-QGHSTRIE 2233
            P  L K+R +E  +G  T+++
Sbjct: 885  PIILSKLRPVETEEGEETKLK 905



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 45/149 (30%), Positives = 64/149 (42%), Gaps = 6/149 (4%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I+HL +   KEG  +  EC V  S  P   IEW+ +     +  R  +T D S  S+  T
Sbjct: 1671 ITHLISKEVKEGGTVTLECTV--SGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFT 1728

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLA 2896
                 D G Y C ATN  GSA +S  L  T    +    +  Q    LE VE +E     
Sbjct: 1729 DAQGFDDGEYKCVATNPLGSAQSSARLTVT----VPSKPEFKQKLRPLEVVEGSEAKFDV 1784

Query: 2897 KGRRPSVPDTEYPKPEWIIPIAAEHQLVE 2925
            + +    P+ E+ +    I  +  HQ+ E
Sbjct: 1785 RIKSYPKPEVEWYRGTTKITDSLRHQITE 1813



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 52/217 (23%), Positives = 90/217 (41%), Gaps = 39/217 (17%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F   +  +  + +G   ++D  L   G P  ++EW+ NE+LI  +SR+  +      +
Sbjct: 2157 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKK--IQKLEQP 2493
            + + +V  +D G+Y C+A N  G               I ++ + PEG +   +  L+  
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAG--------TGSKQFNINVQPKRPEGTEPNIVSGLKSV 2266

Query: 2494 HERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
              +  E+ + EF       V++G                     P+   EWY +G+ +K 
Sbjct: 2267 EVKEGEQAELEF-------VVSG--------------------TPTPTLEWYRDGLRVKE 2299

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
              R R+T + G   L I    A D G Y C+  N  G
Sbjct: 2300 SRRVRSTLENGIARLVITETWAEDMGTYKCQVRNDLG 2336



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 11/157 (7%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHY 982
            EG     E R+    + T  + WLKDG      +RI T+F+     LTI+ V + D G Y
Sbjct: 2564 EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIY 2621

Query: 983  TCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQK 1042
             C A N+ G A +SA LT++ ++        P  LEK+Q ++  S   +R   +++++  
Sbjct: 2622 RCNAKNSSGSAHSSAELTVLERE------ARPRILEKLQDVD--SSVGERAMFKIRVSGS 2673

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEW 1079
            P  +      ++ +     H+  R E +   ++T+E+
Sbjct: 2674 PMPVVQWYRRDEEIT-TKGHYIVRDEGRGYFSLTIEY 2709



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 67/272 (24%), Positives = 109/272 (40%), Gaps = 43/272 (15%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            ++T+ +E   P RF  ++K++  V EG  V    RV   G P   I+W  +G+     + 
Sbjct: 482  QLTVNEELIGP-RFE-KMKESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNN 537

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
            V T        L I+     D+G Y C A NK G+A  T ++    K+        P+G 
Sbjct: 538  VDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKK--------PKGT 589

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
            + E + EL            P+ +T              E +     C +  K  P   I
Sbjct: 590  APEIVSEL-----------RPVEAT--------------EGDDAVLSCTISGKPVP--TI 622

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKATISC 3921
            EW +NG  +    R +     G V L I    A+D G+Y C   N+ G  E  TK  +  
Sbjct: 623  EWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIA 682

Query: 3922 KKLPDIILQNQVPRGMKRSEALTQMEATIKKY 3953
               P+   + +  + ++  E   Q++  ++ Y
Sbjct: 683  FARPEFRTKLKPVKAVEGEE--VQLDVKVEGY 712



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 3/97 (3%)

Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475
            +G  P     L ++E ++EGE A  E  ++ T  P L  EWY +G  +K   R R+  + 
Sbjct: 2253 EGTEPNIVSGLKSVE-VKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLEN 2309

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            G   L I+ T+ ED G Y C+  N+ G   T+A + +
Sbjct: 2310 GIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 45/137 (32%), Positives = 61/137 (44%), Gaps = 11/137 (8%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +S L ++  KEG+    E  V  +  PTL  EW+ +   +    R +ST +     L IT
Sbjct: 2260 VSGLKSVEVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVIT 2317

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLA 2896
             T+ ED G Y C+  N  G  +TS  L      NI   T+ P+ K  L  VE  E  R  
Sbjct: 2318 ETWAEDMGTYKCQVRNDLGRTSTSAHL------NIIVATR-PEFKEKLTKVEVTEGDRAK 2370

Query: 2897 KGRRPSVPDTEYPKPEW 2913
               R  V    YP+ EW
Sbjct: 2371 FEVR--VKGYPYPEVEW 2385



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 57/237 (24%), Positives = 98/237 (41%), Gaps = 13/237 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF---G 3104
            PEF T  K +  + EG+    +  +   G     IEW+     I  S R + +      G
Sbjct: 686  PEFRTKLKPVKAV-EGEEVQLDVKV--EGYPKPDIEWYRGTTMIVESGRFKVMEEEEEDG 742

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +  L I   +  D+GT    ATN  G+A     LE   K +   P F    +    + +G
Sbjct: 743  LYSLVISKLQLDDTGTIKVVATNASGKATSRADLEV--KEREFAPEFEGDEEGPIVVTEG 800

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                 +  V    +P+  ++W+ +G+P+  ST+           L I  +   D+G Y C
Sbjct: 801  NEVSIQLRVKA--NPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKC 858

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEP 3281
             A N+ G+      +    KG    +   P  L+K+R +E+ +G + +   T + +P
Sbjct: 859  EASNRLGKASRSFDVKVQVKGP---KGEAPIILSKLRPVETEEGEETKLKCTFTGKP 912



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 80/353 (22%), Positives = 135/353 (38%), Gaps = 26/353 (7%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+ + ++K+  V E    +  CRV     P   IEWY++   L    R    +      L
Sbjct: 2847 PEIVQRLKACEVPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQYFL 2904

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKA------TISCKKLPDIILQNQVPRGMK-RSEA 3942
            + L   A D G Y+  A N  G   T A      ++S       +   +V  G + R + 
Sbjct: 2905 NFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVSPPSFRHRLTAVEVDEGDETRFDV 2964

Query: 3943 LTQMEAT-IKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVG 4001
              + E T ++ Y  +  +  D  ++V + +     + + S T + +    K    L   G
Sbjct: 2965 RLKKEPTSVEWYKEQQRIFTDGHFEVIEGEEECLYSLVISNTKVADAGGYKCTA-LNESG 3023

Query: 4002 DPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS-------GEYLCRATNLY 4054
              + + E   N + L+      P  D G   +  G     D+        E         
Sbjct: 3024 KSSTRAELLVNER-LIPPGFEGP--DHGSYELQEGDTITLDAVVKGNPYPEIRWYKDEFL 3080

Query: 4055 GMDETKAVIKTTG-KPGIVYDSQLPKHM---KSIEKIREMEASWQVTPEQVVEESKARCP 4110
             M+  K ++     K  +     +PK     K + K +   A+   T +   ++SK   P
Sbjct: 3081 AMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKSKGIIP 3140

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
              F  L     V+ G  ARF C+V+GHP+P++ WL +G  +      K  YDG
Sbjct: 3141 EFFRQLRRVEAVQ-GSTARFECKVSGHPEPQIAWLKDGKELAIPRYIKPFYDG 3192



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 2/95 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+F + +  V   EG +  FE R+E  G P +++EW K    IE S R+T        ++
Sbjct: 1189 PEFKIKMSPVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRYTM 1246

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
             + ++ ++D+G Y C A +  G   ++A L V  R
Sbjct: 1247 VIANVTLEDAGGYRCVATNTAGKTTSRADLTVKER 1281



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 6/135 (4%)

Query: 3821 KEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            +++ ++   P  IT + S  V+E   V  EC V  K  P   IEWY++G    +  R  T
Sbjct: 1659 QKKKVIGNAPDIITHLISKEVKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMT 1716

Query: 3881 VYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKATISCKKLPDIILQNQVPRGMK 3938
             +D    S+        D GEY C A N  G  +   + T++    P+   + +    ++
Sbjct: 1717 TFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSKPEFKQKLRPLEVVE 1776

Query: 3939 RSEALTQMEATIKKY 3953
             SEA  + +  IK Y
Sbjct: 1777 GSEA--KFDVRIKSY 1789



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 49/190 (25%), Positives = 82/190 (43%), Gaps = 10/190 (5%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G+ P FT+     V++ EG     +   + +G     ++W  +G  +   +RI    +  
Sbjct: 1960 GQAPSFTSEMSQ-VEVDEG--GEVKLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRV 2016

Query: 3105 MVVLEILGTKTT-DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
              V  I+   T  D G Y C   N+ G    +V++    +S   +P F   ++N+EG + 
Sbjct: 2017 QGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRSI--RPIFGQKMKNVEG-RI 2073

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDF-GFVVLDIAYTQNHDSGEY 3222
            G+   FE  V     P   + ++   + +    R   V +  G  VL I  T+  D+GEY
Sbjct: 2074 GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEY 2131

Query: 3223 VCRAYNKYGE 3232
             C A N  GE
Sbjct: 2132 QCIAVNGAGE 2141



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 4/95 (4%)

Query: 2364 RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS 2423
            R E+P+P T + P   Q LQ +D I EG+    +CR+    +PT  + W ++  +    +
Sbjct: 2540 RVEVPKP-TGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDN 2595

Query: 2424 RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            RI    D    ++TI  V+  DEG+Y C A N  G
Sbjct: 2596 RIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSG 2630



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 6/124 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P F  Q++ +   V+  T +FEC+++  G P  ++ W  +GK L       P YD     
Sbjct: 3140 PEFFRQLR-RVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCK 3196

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA 4092
            + F    PED G+Y C A+N  G   + A +    KP ++   +  + +K+I+ +   EA
Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVM--PEFKERLKNIKVVEGDEA 3253

Query: 4093 SWQV 4096
             + V
Sbjct: 3254 QFSV 3257



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 35/100 (35%), Positives = 50/100 (50%), Gaps = 5/100 (5%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRF-RPAYEFDYVA 1369
            P+F   L NI+ VEG       R++  G+   +VEWF  GK IK+  RF   A E     
Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409
            L +  V  ED G Y C A+N  G+    C+ R+  K+ ++
Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGK--VQCSGRLDVKERMV 3331



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 30/91 (32%), Positives = 41/91 (45%)

Query: 74   FEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLI 133
            F+Q  K+     G    F+ ++ G P P V W +    LVE  +       +TG  SLLI
Sbjct: 5009 FQQELKDREVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIFVSEPETGLYSLLI 5068

Query: 134  KQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            K+    DEG+Y C A N  G   C   +  E
Sbjct: 5069 KKATLDDEGDYRCVAANPAGTISCQAELLVE 5099



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 3/98 (3%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            + KG +P+    ++ ++ +K+ ++A   CT+     P+   EWY +   +R S RIK+  
Sbjct: 3    RPKGDRPQILQPLEGVD-VKEDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSEV 59

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
              G   L I  T+  D GEY C   N++G   ++A +N
Sbjct: 60   VNGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLN 97



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 2/104 (1%)

Query: 759  QESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR 818
            ++S  + T + P  IR LQ   E+ EG  A+   ++T  + P   ++W +DG  I  +SR
Sbjct: 1362 KQSAPKTTGEEPIIIRKLQ-AQEIDEGSTANLVCKVT-AAKPEPSIKWTRDGVKIRENSR 1419

Query: 819  ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            I  +F+    SL I     +D G Y V   N+ G A ST  + V
Sbjct: 1420 IKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLV 1463



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 8/183 (4%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            +I EG  A+    +     +   I+W  +G  I  + RI+ V+      L I      D 
Sbjct: 1383 EIDEGSTANLVCKVTAAKPEPS-IKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDE 1441

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            G Y    TN++G A  + ++  +    G +P F   ++ +  + +G+S  FE  +  +  
Sbjct: 1442 GVYKVTLTNEYGTASSTCRV--LVNEVGSRPIFQQKLKAVSTI-EGESTRFEVKLSAMPR 1498

Query: 3179 PDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
            P   +EW+ +   +    R  I    + G  VL I  T   D+G Y   AYN  G+  ++
Sbjct: 1499 P--TVEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQ 1556

Query: 3237 ATI 3239
            A +
Sbjct: 1557 ALL 1559



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 8/128 (6%)

Query: 2079 TLDEQRLKKIQELEKYERPKP---IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEP 2135
            TLD++ + K+    +Y        +   + G RP+F   L ++  + EG+   FE ++  
Sbjct: 1437 TLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKLKAVSTI-EGESTRFEVKLSA 1495

Query: 2136 INDPHLTIDWFHNGQKIRAGHRYRTTHD--FGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            +  P  T++WF +  +I  G R+  T +   G   L I  T  ED+GTY   A N LG+ 
Sbjct: 1496 M--PRPTVEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKV 1553

Query: 2194 VNTCTLKV 2201
             +   L+V
Sbjct: 1554 TSQALLRV 1561



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 4/100 (4%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            PE T+ P   + +K  + +KEG  A  E  +   G  T  +EW +DG  V+ S R+ +  
Sbjct: 2252 PEGTE-PNIVSGLKS-VEVKEGEQAELEFVVS--GTPTPTLEWYRDGLRVKESRRVRSTL 2307

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
              G   L I      D G Y C+  N +G+ +TSA+L I+
Sbjct: 2308 ENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNII 2347



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 5/106 (4%)

Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
           RPQ ++PL+ + +++E  NA     ++    PT   EWY+D   +  S RI S    G  
Sbjct: 8   RPQILQPLEGV-DVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64

Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTA--SIRVAARSTVTADL 872
           +L I   RAED G Y     N+ G A S A  ++RV  + + T+ +
Sbjct: 65  TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVPVKPSFTSKM 110



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 9/183 (4%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            VD+ E + A    ++  +G  +   EW+ +   +  S RI++    GM  L I  T+  D
Sbjct: 18   VDVKEDENAILSCTI--SGTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTRAED 75

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVD 3177
             G Y C   N+ G A     L   +     KP FT+ ++ ++  ++GQ   F+  V    
Sbjct: 76   QGEYKCVLRNEHGTATSKAPL---NVRVPVKPSFTSKMKPVDA-EEGQEVRFDVHVKGSP 131

Query: 3178 DPDMKIEWYHNGQPMRHSTRIKTV-SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
             PD  + WY     +    R + V +    V L I+  +  D+  Y   A N  G+  +R
Sbjct: 132  KPD--VVWYKGSTMIGTHERFQIVEAAEDHVTLVISEVKLEDAETYKVVATNDVGKVTSR 189

Query: 3237 ATI 3239
            A +
Sbjct: 190  ADL 192



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 6/101 (5%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK---STFDFG 2698
            P F T LK   K VEG+ V L+ +VE    P+  IEW++    +    R K      + G
Sbjct: 686  PEFRTKLKPV-KAVEGEEVQLDVKVEGYPKPD--IEWYRGTTMIVESGRFKVMEEEEEDG 742

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHW 2739
            L +L I+ L+ DD+G     ATN  G+A S A +++++R +
Sbjct: 743  LYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKEREF 783



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 55/221 (24%), Positives = 89/221 (40%), Gaps = 27/221 (12%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSL 701
            LK VT M G +  F  R+    +    ++W K+   +    RF       G  SL +  +
Sbjct: 989  LKDVTVMPGEEAEFSIRVSGRAE----VDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDV 1044

Query: 702  NIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQES 761
              +D G Y C   + +G   T+A L       I+     PE +   + +           
Sbjct: 1045 RPEDKGTYKCLVFNESGKVTTRAKL------CIKEAIVAPEEVDAAETVP---------- 1088

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            IE      P+  +PL+ + E+ EG +   E  ++    PT  VEW KD   +  S R+  
Sbjct: 1089 IE---GSAPKITKPLESV-EVNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRTSYRLKE 1142

Query: 822  IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
              +     L     R ED G Y    +N+ G+A +T  ++V
Sbjct: 1143 KLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 47/168 (27%), Positives = 71/168 (42%), Gaps = 14/168 (8%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474
            E G  P+F   L  +  + EGE+  FE +L+    P   VEW+ +   +  G RF    +
Sbjct: 1465 EVGSRPIFQQKLKAVSTI-EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEE 1521

Query: 3475 --FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTI 3532
               G  +L I  T  ED+G Y   AYNN G+  + A ++V     ++   +     EG I
Sbjct: 1522 ENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV---NEVLTVPEFMDKAEGPI 1578

Query: 3533 DKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECR 3580
            +K        G    LT        PE      D  L ++S  +F+ R
Sbjct: 1579 EKT------EGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSR 1620



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 5/123 (4%)

Query: 1820 KIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879
            K Q   D  R      + + V   P F  +L    +++EG  A +E R++ YP P   VE
Sbjct: 2328 KCQVRNDLGRTSTSAHLNIIVATRPEFKEKLT-KVEVTEGDRAKFEVRVKGYPYPE--VE 2384

Query: 1880 WYFNGKVLQSGHRYRTSN--DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            WY     +    R+   +  + G+ +L +  V  ED+G Y C A+N  G++     L V 
Sbjct: 2385 WYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVN 2444

Query: 1938 SKE 1940
             ++
Sbjct: 2445 ERQ 2447



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 40/141 (28%), Positives = 64/141 (45%), Gaps = 11/141 (7%)

Query: 1820 KIQQLEDSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
            K+    D  +   R D+ V   Q AP FI +  GP   + G      C +   P P+  +
Sbjct: 176  KVVATNDVGKVTSRADLRVKERQFAPEFIDEERGPIDATTGDEVTLTCSVSGKPKPS--I 233

Query: 1879 EWYFNGKVLQSGHR--YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             WY NGK+L    +   R+S +  +  +  L+   ED+  Y C+A N LG+A  +  + V
Sbjct: 234  TWYKNGKLLTDSLKLDIRSSGERNWVTM--LSAKPEDTALYKCEAENKLGKASRAFDVKV 291

Query: 1937 QSKE----SIIRDSQHESALE 1953
            ++ +    S   D  H  A+E
Sbjct: 292  KAPKGDAPSFTIDLTHVRAIE 312



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 57/231 (24%), Positives = 97/231 (41%), Gaps = 41/231 (17%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP FT+ +  +R  E + +    ++   G P   +EWL+  +P+  S R+ T  +     
Sbjct: 298  APSFTIDLTHVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDFEKNVAT 355

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829
            L +K     D+GTY   A N+ G A + + L VQ +++               ++EDS R
Sbjct: 356  LVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTK-------------PEIEDSLR 402

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
                 DV     +  +F  ++ G                +P P    +VEW     V++ 
Sbjct: 403  -----DVSALPGERVKFKVRIGG----------------KPKP----KVEWRKGKSVIED 437

Query: 1890 GHRYRTSNDFG-FAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            G R+  + +     +L I  +   D+G Y C A N  G+A S  +L V  +
Sbjct: 438  GERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEE 488



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 51/195 (26%), Positives = 85/195 (43%), Gaps = 10/195 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV- 3106
            PEF    +  + ++EG        L    + +  ++WF +G+ I  S + R +   G   
Sbjct: 785  PEFEGDEEGPIVVTEGN--EVSIQLRVKANPNADVDWFKDGRPIYESTK-RDIKRRGEEH 841

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEIS--VKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
             L I  +   D+G Y C A+N+ G+A  S  VK++ V   KG+ P   + ++ +E  ++G
Sbjct: 842  TLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQ-VKGPKGEAPIILSKLRPVE-TEEG 899

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +    +CT      P    EW  +G  +R S  ++  +      L I  T   D G Y C
Sbjct: 900  EETKLKCTF--TGKPAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKC 957

Query: 3225 RAYNKYGEDFTRATI 3239
               N  G   T A +
Sbjct: 958  TIKNDLGTVSTSAEV 972



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 61/245 (24%), Positives = 91/245 (37%), Gaps = 31/245 (12%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S + + L  E E G  P       D+ +     A F  R+         V+WF +   L 
Sbjct: 967  STSAEVLVNEVEKGVGPVIEEKLKDVTVMPGEEAEFSIRV----SGRAEVDWFKDEVMLN 1022

Query: 3602 TGSR-VKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
               R +    D G   L I  V   D G Y C   N  G+ T   KL +K          
Sbjct: 1023 DEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCIK---------- 1072

Query: 3661 LPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVE 3720
                     E+I   EE +   E + IE    + P+ T  + ++++V EG     +C V 
Sbjct: 1073 ---------EAIVAPEE-VDAAETVPIEG---SAPKITKPL-ESVEVNEGEDFDLECVVS 1118

Query: 3721 PVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
              G P+  ++W  +     T  R+    D     L        D GEY C   N+ G A+
Sbjct: 1119 --GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKAS 1176

Query: 3781 TTAKI 3785
            TT ++
Sbjct: 1177 TTGEV 1181



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 2/81 (2%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            +V EGG V  +C V   G P   I+W+ +G  F    RV T  D    ++        D 
Sbjct: 1678 EVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDD 1735

Query: 3766 GEYTCRATNKWGSATTTAKIT 3786
            GEY C ATN  GSA ++A++T
Sbjct: 1736 GEYKCVATNPLGSAQSSARLT 1756



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 39/137 (28%), Positives = 59/137 (43%), Gaps = 10/137 (7%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980
            +KEGG    E  +   G     +EW KDG    A+ R+ T F+    ++T       D G
Sbjct: 1679 VKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDG 1736

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKIT 1040
             Y C A N +G A +SA LT+            P   +K++ LE       + +  +K  
Sbjct: 1737 EYKCVATNPLGSAQSSARLTVTV-------PSKPEFKQKLRPLEVVEGSEAKFDVRIKSY 1789

Query: 1041 QKPRFLGPLKGTNKIVE 1057
             KP  +   +GT KI +
Sbjct: 1790 PKPE-VEWYRGTTKITD 1805



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 31/87 (35%), Positives = 41/87 (47%), Gaps = 2/87 (2%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P   + LK+VE+KEG++A  E   +     T  +EWY +   +K   R   T   G   L
Sbjct: 2257 PNIVSGLKSVEVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVRSTLENGIARL 2314

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTS 1664
             I     ED GTY C+  N LG   TS
Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTS 2341



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 33/102 (32%), Positives = 49/102 (48%), Gaps = 3/102 (2%)

Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468
            D   ++ KG  P F   L  +E + +G  A FE +++   +P  ++ W  +GK L     
Sbjct: 3129 DVEAKKSKGIIPEFFRQLRRVEAV-QGSTARFECKVSGHPEP--QIAWLKDGKELAIPRY 3185

Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASM 3510
             + F D     L    T PED G+Y C A N  GEA + AS+
Sbjct: 3186 IKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASL 3227



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 49/163 (30%), Positives = 70/163 (42%), Gaps = 12/163 (7%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F  P+ DQ  + EG     E R+         VEW KDGR  +    I T F+  +  
Sbjct: 3431 PLFIAPLHDQ-EVVEGETIRLECRVR--ATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCT 3487

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L IK   + D G Y C A N  G+  + A LT V +  II    HP  ++ +  +E    
Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRGRSVAQLT-VKEALIIPHFDHP--IQDLDVIE---- 3540

Query: 1029 YSKRTEEEVKITQKPRF-LGPLKGTNKIVEGQSAHFEARVEPQ 1070
               R +  V+++ KP   +  LKG  ++  G     E   E Q
Sbjct: 3541 -GDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQ 3582



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 90/386 (23%), Positives = 157/386 (40%), Gaps = 44/386 (11%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM- 3884
            V   P F +++K    EE + VRF+  V  K  PK  + WY+   ++ +  R++ V    
Sbjct: 100  VPVKPSFTSKMKPVDAEEGQEVRFDVHV--KGSPKPDVVWYKGSTMIGTHERFQIVEAAE 157

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPRGMKRSE 3941
              V+L I  V  ED+  Y   A ND G+  ++A +  K+    P+ I + + P      +
Sbjct: 158  DHVTLVISEVKLEDAETYKVVATNDVGKVTSRADLRVKERQFAPEFIDEERGPIDATTGD 217

Query: 3942 ALT-------QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQ---TSLVEME-- 3989
             +T       + + +I  Y +   LT+    D+       +VT + ++   T+L + E  
Sbjct: 218  EVTLTCSVSGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAE 277

Query: 3990 ------TTKFECQL-APVGD-PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPE 4041
                  +  F+ ++ AP GD P+  ++   + + +  +         G  A    W+  E
Sbjct: 278  NKLGKASRAFDVKVKAPKGDAPSFTID-LTHVRAIEGEESKLVCKVTGKPAPTIEWLKGE 336

Query: 4042 DSGEYLCRATNLYGMDETKAVIKTT--GKPGIVYDSQLPKHMKSIEKIREMEASWQVTPE 4099
                   R    +  +    VIK T  G  G  Y         +   I E+         
Sbjct: 337  LPVTTSLRVRTDFEKNVATLVIKDTRLGDAG-TYKVVARNDSGTAHSIAEL--------- 386

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            QV E S    P +  SL D V+   GE  +F  R+ G PKP+V W    + I +G R+ +
Sbjct: 387  QVQERSTK--PEIEDSLRD-VSALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERFTI 443

Query: 4160 T--YDGMYHFDIPKTRQYDTGKIEVI 4183
                D ++   I    + D G+ + +
Sbjct: 444  AEESDEVFSLIIQDLEETDAGRYKCV 469



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 34/94 (36%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            RP F   ++ +E + EG  A FE RVE    P L ++WF    KI    RY  T D    
Sbjct: 1188 RPEFKIKMSPVE-VTEGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             + I     ED+G Y C ATN  G+  +   L V
Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 60/231 (25%), Positives = 97/231 (41%), Gaps = 41/231 (17%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR--TTHDFG 2564
            +P F + LT   E+ EG  A +E RV   G P    EWY     +    RF   +  + G
Sbjct: 2351 RPEFKEKLT-KVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETG 2407

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEA 2624
            + +L +  VV  DAG+Y C A                     +++A +      +++ E 
Sbjct: 2408 YYSLTVGEVVQEDAGMYKCIA---------------------VNKAGKSTCRADLEVNER 2446

Query: 2625 AMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684
                 PE   +TG ++ PI            EG    L+  +  R +P  ++ W+K+G  
Sbjct: 2447 QF--APEF--ETGEERGPIVVP---------EGGETTLKVTL--RANPKPQVIWYKDGKH 2491

Query: 2685 LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             +   RL          L I + + +DSG Y C+A N LG A  + +I++E
Sbjct: 2492 TSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADKSFTIRVE 2542



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 8/119 (6%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            + P   + L  ++T+EG  + +ECR+    + T  + W  +G    T +R +  ++ D  
Sbjct: 2549 EEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVC 2606

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
             L +  V   D G+Y C A N  G A +S  L V+ ++        P  LEK+Q ++ +
Sbjct: 2607 TLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLERE------ARPRILEKLQDVDSS 2659



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 10/156 (6%)

Query: 1835 DVEVAVNQA--PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            DVE   ++   P F  QL    +  +G +A +EC++  +P+P  ++ W  +GK L     
Sbjct: 3129 DVEAKKSKGIIPEFFRQLRR-VEAVQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRY 3185

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952
             +   D     L       ED G+YTC A N  G+A S   L V SK  ++   + +  L
Sbjct: 3186 IKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVM--PEFKERL 3242

Query: 1953 EKIQYLE-DDSRYK-RAVQDDSFVVEKPQFGKPIKN 1986
            + I+ +E D++++  R   +    VE  + GK IK+
Sbjct: 3243 KNIKVVEGDEAQFSVRVKGEPEPKVEWFKTGKKIKS 3278



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 2/108 (1%)

Query: 60   PITAGRPGE--PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNK 117
            P TA +P +     P+F  + K+     G  A+F+ ++ G PTP V+W R+   +   + 
Sbjct: 5114 PATAPKPAKRKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSH 5173

Query: 118  YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
              M+   +    SLLI + G  D G Y C A+N  G+     ++  EG
Sbjct: 5174 PHMKALHEGEVHSLLITEGGYKDSGVYKCIAKNSAGQDTTVGHLFVEG 5221



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 3/97 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP FT  L ++ + +EG+   L  +V  +  P   IEW K  + +TT  R+++ F+  + 
Sbjct: 298  APSFTIDL-THVRAIEGEESKLVCKVTGKPAPT--IEWLKGELPVTTSLRVRTDFEKNVA 354

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            TL I   R  D+G Y   A N  G A S A +++++R
Sbjct: 355  TLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQER 391



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP  +++L  P + +EG  A   C I   P P   +EW  NG  ++   R +     G  
Sbjct: 590  APEIVSELR-PVEATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEV 646

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             L I T   +D G+YTC   N LG A S  +L V
Sbjct: 647  KLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 38/123 (30%), Positives = 56/123 (45%), Gaps = 3/123 (2%)

Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTM 1075
            G  K   + +  + S   E +V +  +P F   +    ++ EG  A FE RVE    L  
Sbjct: 1162 GEYKCTVINEHGKASTTGEVKVNVLSRPEFKIKMSPV-EVTEGSEAAFEVRVEGFPKLQ- 1219

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             VEW+    +I  + R     D     + IA+V  ED+G Y  VA N AG+    A +TV
Sbjct: 1220 -VEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278

Query: 1136 ETR 1138
            + R
Sbjct: 1279 KER 1281



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 39/106 (36%), Positives = 52/106 (49%), Gaps = 5/106 (4%)

Query: 765  QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSI 822
            +   RP F + L+ +  + EG +  FE +L+ +  PT  VEW+K    I    R  IT  
Sbjct: 1465 EVGSRPIFQQKLKAVSTI-EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEE 1521

Query: 823  FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
             N G   L I     EDAG+Y V A N LG+  S A +RV    TV
Sbjct: 1522 ENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLTV 1567



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P     L ++E  EG    LE  +   G  T  +EW+ +G  +K   R R   E     L
Sbjct: 2257 PNIVSGLKSVEVKEGEQAELEFVVS--GTPTPTLEWYRDGLRVKESRRVRSTLENGIARL 2314

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             +   + ED G Y CQ  N LG   TS  L +I
Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTSAHLNII 2347



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 35/108 (32%), Positives = 53/108 (49%), Gaps = 4/108 (3%)

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
            GR S +     IV+T P+F  ++    V E +  +FE RV  K  P   +EWY     + 
Sbjct: 2336 GRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRV--KGYPYPEVEWYHGSNRIL 2393

Query: 3874 SGHRYR--TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               R+   +V + G+ SL +  V  ED+G Y C AVN  G+   +A +
Sbjct: 2394 DEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR--NEKLIEDSSRITKT 2428
            +   RP F + L  ++ + EG  A F+ R+   G P  +VEW+   N  L ED   I   
Sbjct: 2347 IVATRPEFKEKLTKVE-VTEGDRAKFEVRV--KGYPYPEVEWYHGSNRILDEDRFEIESV 2403

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             + GY S+T+  V  ED G+Y C A N  G+
Sbjct: 2404 KETGYYSLTVGEVVQEDAGMYKCIAVNKAGK 2434



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 3/98 (3%)

Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475
            KG  P    PL  ++ ++E ENA     ++ T  PN   EWY +   ++   R ++    
Sbjct: 5    KGDRPQILQPLEGVD-VKEDENAILSCTISGTPTPN--AEWYRDSIRVRESRRIKSEVVN 61

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            G   L I  T  ED GEY C   N +G A + A + V+
Sbjct: 62   GMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            RP   QPL+ +D ++E + A   C +   G PT   EW+R+   + +S RI      G  
Sbjct: 8    RPQILQPLEGVD-VKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64

Query: 2435 SMTISHVRDEDEGVYMCRASN 2455
            ++TI   R ED+G Y C   N
Sbjct: 65   TLTIKQTRAEDQGEYKCVLRN 85



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP   + L+  +   EG    L   +  +  P   IEW KNG+ +    R K     G V
Sbjct: 590  APEIVSELRPVEA-TEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEV 646

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             L+I + R DD G YTC   N LG A S   +K+
Sbjct: 647  KLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 40/134 (29%), Positives = 66/134 (49%), Gaps = 7/134 (5%)

Query: 3793 IVLESQLPQGMSGEKIKEL-ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG--VRF 3849
            +V +   P+ +   K   + E G+ S   + +  V + P+F  +IK   VE +EG    F
Sbjct: 1151 LVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSRPEF--KIKMSPVEVTEGSEAAF 1208

Query: 3850 ECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVND 3909
            E RVE    PKL++EW++    +    RY    D    ++ I  V  ED+G Y C A N 
Sbjct: 1209 EVRVEGF--PKLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNT 1266

Query: 3910 FGEDFTKATISCKK 3923
             G+  ++A ++ K+
Sbjct: 1267 AGKTTSRADLTVKE 1280



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 3/118 (2%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            V   V   P F   +   + + EG     E +VE    P L++EWFK    +    R   
Sbjct: 1181 VKVNVLSRPEFKIKMSPVE-VTEGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDSGRYTF 1237

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLD 2751
            T D    T+ I ++  +D+G Y C ATN  G+  S A + +++R +        D++D
Sbjct: 1238 TADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTID 1295



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 3/99 (3%)

Query: 3274 PSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT 3333
            P  P    P  ++ ++ V ++ EG+ A  E   V    P   +EW+ +G ++    R R+
Sbjct: 2249 PKRPEGTEPNIVSGLKSV-EVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVRS 2305

Query: 3334 FHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              + GI  L I   + E+ G Y+C   N LGR ST A+L
Sbjct: 2306 TLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHL 2344



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 5/131 (3%)

Query: 1275 IVTDTQNEQ-AIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
            ++T+T  E     + Q+  D  R +     +I V   P+F   L  +E  EG     E R
Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVR 2374

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRF--RPAYEFDYVALDLLSVYPEDSGVYTCQATNQL 1391
            ++  G     VEW+     I    RF      E  Y +L +  V  ED+G+Y C A N+ 
Sbjct: 2375 VK--GYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKA 2432

Query: 1392 GEAVTSCALRV 1402
            G++     L V
Sbjct: 2433 GKSTCRADLEV 2443



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 59/219 (26%), Positives = 87/219 (39%), Gaps = 41/219 (18%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGF 3752
            P F  ++   ++V EG    F+ RV+  G P   ++W+H         R  + ++ + G+
Sbjct: 2352 PEFKEKLT-KVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETGY 2408

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELE 3812
             +L +  +   DAG Y C A NK G      K TC A  ++      P+  +GE     E
Sbjct: 2409 YSLTVGEVVQEDAGMYKCIAVNKAG------KSTCRADLEVNERQFAPEFETGE-----E 2457

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
            RG         PIV  P               EG     +V  + +PK ++ WY++GK  
Sbjct: 2458 RG---------PIV-VP---------------EGGETTLKVTLRANPKPQVIWYKDGKHT 2492

Query: 3873 PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                R           L I     EDSG Y C A N  G
Sbjct: 2493 SENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLG 2531



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 37/129 (28%), Positives = 67/129 (51%), Gaps = 7/129 (5%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            PEF   ++ ++   +G  A FE ++   G    ++ WLKDG+ +     I  F++     
Sbjct: 3140 PEFFRQLR-RVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCK 3196

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE-DAS 1027
            LT       D G YTC A N  G+A++ A+L +++K  ++ E +    L+ I+ +E D +
Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVMPEFKE--RLKNIKVVEGDEA 3253

Query: 1028 RYSKRTEEE 1036
            ++S R + E
Sbjct: 3254 QFSVRVKGE 3262



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 34/85 (40%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT-KTHDFGYV 2434
            P F + L+NI  + EG  A F  R+   G+P  KVEWF+  K I+  +R + K  +    
Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
            ++TIS V  ED G Y C ASN  G+
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGK 3317



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 60/237 (25%), Positives = 101/237 (42%), Gaps = 38/237 (16%)

Query: 2224 EAQGHSTRIEV-EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNG 2282
            E+   STR E+    ++ PP F     G+  + EG T   +  V+   +P   I +Y + 
Sbjct: 3021 ESGKSSTRAELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVKG--NPYPEIRWYKDE 3078

Query: 2283 KALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIIS 2342
                 + +  ++      SL + H +P+D+G Y     N +G  T   S TV        
Sbjct: 3079 FLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATK--SFTVDV------ 3130

Query: 2343 ESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIP 2402
            E+++ +G+                IPE        F + L+ ++ +Q G TA F+C++  
Sbjct: 3131 EAKKSKGI----------------IPE--------FFRQLRRVEAVQ-GSTARFECKVS- 3164

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             G P  ++ W ++ K +     I   +D     +T    + EDEG Y C ASN  GE
Sbjct: 3165 -GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGE 3220



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 36/97 (37%), Positives = 48/97 (49%), Gaps = 4/97 (4%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV- 1101
            P F   LK   K+VEG  A F  RV+ + +    VEW+  GK+I S  R  +     +  
Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRVKGEPE--PKVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
             L I+ V  ED G Y  VA N AG+ Q S  + V+ R
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 36/162 (22%), Positives = 72/162 (44%), Gaps = 4/162 (2%)

Query: 198  TEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLRE--VSFRESITKRYVGESDVQISTE 255
            T++ R        +GTD SS      +  +   ++E  +S  +S +   +   D+ ++  
Sbjct: 4274 TDEGRYKCVAKNKSGTDFSSATVKVKELDDEDSIQEGAMSLPKSTSDEALRMEDIPVAQS 4333

Query: 256  IDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEII 315
                 G   PP+  +K R+  +QE   A+F  ++ G P P   W +  + + +  ++ I+
Sbjct: 4334 TPLKRG--EPPEFIRKLRDQFIQEKETARFVCRVIGRPDPTYEWLRGDKPITDGGRYTIM 4391

Query: 316  TTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            +     TL + +    D G Y  ++ N +G   T+  L VE+
Sbjct: 4392 SDDEGQTLEITDCTVEDEGLYKCVSTNSSGTDTTTARLTVEA 4433



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 1/90 (1%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            E   P+F Q  +  R  +G  A+F  K+ G+P P V W   +  + E ++  +   +  G
Sbjct: 4513 ESGEPVFVQKPETCRLKEGDTARFNVKVNGSPEPFVDWFLGRRMIEEDDRIRIEEGD-VG 4571

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
            + SL+I  I   D G Y C A N  G   C
Sbjct: 4572 ECSLVIMDIDREDAGVYKCVAENDDGSISC 4601



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 2232 IEVEEPKI--SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA 2289
            ++V++ K+  + P  +T L  +  V EG T   EC V     PN  IE+Y +G    +  
Sbjct: 1656 LDVQKKKVIGNAPDIITHLI-SKEVKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATR 1712

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG 2349
            R   TFD    S+        D GEY   A N LG   S+  +TVT          +PE 
Sbjct: 1713 RVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTV-------PSKPEF 1765

Query: 2350 LEKIRELESAE 2360
             +K+R LE  E
Sbjct: 1766 KQKLRPLEVVE 1776



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 4/122 (3%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
            I  +   + G  + QV  D  +   +  ++ +    P     L  VE+ EG RA FE R+
Sbjct: 2316 ITETWAEDMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRV 2375

Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
                    +VEWYH +  +    RF        G+ +L +   + ED+G Y C A+N  G
Sbjct: 2376 --KGYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAG 2433

Query: 1660 EA 1661
            ++
Sbjct: 2434 KS 2435



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 6/124 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   ++ +   +   A FE ++   G P+ ++ WL++G  +     +   +D     L
Sbjct: 3140 PEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKL 3197

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE-DSSR 1829
                  PED G YTC A NE GEA + ++L V SK  +  E   +  L+ I+ +E D ++
Sbjct: 3198 TFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVMPE--FKERLKNIKVVEGDEAQ 3254

Query: 1830 YQRR 1833
            +  R
Sbjct: 3255 FSVR 3258



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 2/123 (1%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    P+F   +   + + +G   +++  LE  G     +EW  + R + A+SR+   
Sbjct: 2150 VEEELTIPQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLS 2207

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            F      + + +VT+ D+G Y C+A N  G  +   N+ +  K+    E     GL+ ++
Sbjct: 2208 FISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVE 2267

Query: 1022 YLE 1024
              E
Sbjct: 2268 VKE 2270



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 3/106 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+ +  L+ V A EG        I   G P   IEWLKNG  ++ S R       G + L
Sbjct: 591 PEIVSELRPVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKL 648

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIE-RTSQHP 741
            + +    D G+YTC   +  G AE+K  L V   A  E RT   P
Sbjct: 649 TIKTTRADDQGDYTCIVRNELGSAESKTKLKVIAFARPEFRTKLKP 694



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 2/81 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG  + LEC +   G P   +EW+ +G   T   R  T +D    ++    A   D G
Sbjct: 1679 VKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDG 1736

Query: 1249 EYTVRAVNHLGSAHTSAIVRV 1269
            EY   A N LGSA +SA + V
Sbjct: 1737 EYKCVATNPLGSAQSSARLTV 1757



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 40/167 (23%), Positives = 69/167 (41%), Gaps = 8/167 (4%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  +  IEW+ +   ++ + R+   +      L  L T+  D G Y   A N  G   +
Sbjct: 2871 TGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLG--SV 2928

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            S   E + +     P F   +  +E + +G    F+   V +      +EWY   Q +  
Sbjct: 2929 STSAELIIEPSVSPPSFRHRLTAVE-VDEGDETRFD---VRLKKEPTSVEWYKEQQRIFT 2984

Query: 3195 STRIKTV--SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
                + +   +     L I+ T+  D+G Y C A N+ G+  TRA +
Sbjct: 2985 DGHFEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL 3031



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY-IS 695
            P+F   LK++  +EG +  F  R++  G+P  K+EW K G+ I++ +RF+S     +  +
Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            L +  + ++D G Y C A +  G  +    L V  R
Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 4/94 (4%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV- 967
            PEFK  +K+ I + EG  A F  R++  G+   +VEW K G+ +++ +R ++     +  
Sbjct: 3236 PEFKERLKN-IKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             LTI  V + D G Y C A N  G+   S  L +
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV 3326



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 43/154 (27%), Positives = 64/154 (41%), Gaps = 9/154 (5%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F  P+ + EV EG  + LE  +     P   VEW  +GR  ++ +   T +D  +  L
Sbjct: 3431 PLFIAPLHDQEVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYTEFDGQHCTL 3488

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERP 2097
             I  A  ED G Y C A N  G   + + + V  K  L +   D      IQ+L+  E  
Sbjct: 3489 VIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV--KEALIIPHFDH----PIQDLDVIEGD 3542

Query: 2098 K-PIEEEQPGQRPVFLTALTSLENLKEGDRAHFE 2130
            +     E  G+    +  L   + L+ G R   E
Sbjct: 3543 RAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLE 3576



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 90/427 (21%), Positives = 167/427 (39%), Gaps = 40/427 (9%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            ++ ++  K + P FT+++  ++   EG      C+V   G P   I+W     P  T  R
Sbjct: 288  DVKVKAPKGDAPSFTIDLT-HVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLR 344

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITC---SAKRDIVLESQLP 3800
            V T  +     L I      DAG Y   A N  G+A + A++     S K +I    +  
Sbjct: 345  VRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTKPEIEDSLRDV 404

Query: 3801 QGMSGEKIKELERGRISDAPKEE-----PIVSTPPKFITQIKSHTV--------EESEGV 3847
              + GE++K   R      PK E      ++    +F    +S  V        EE++  
Sbjct: 405  SALPGERVKFKVRIGGKPKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAG 464

Query: 3848 RFEC-RVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906
            R++C       + +   +   N +L+  G R+  + +          V   +S E + R 
Sbjct: 465  RYKCVATNEAGEAESMAQLTVNEELI--GPRFEKMKES-------FTVVEGESVELVARV 515

Query: 3907 VNDFGE--DFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDL 3964
                    ++TK   + +K  ++  + +  + +   E  ++ ++ + + T+       D+
Sbjct: 516  TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADM 575

Query: 3965 ---YDVDKKQPPRFVTQIQSQTSLVEM---ETTKFECQLAPVGDPNMKVEWFFNGKPLLH 4018
                DV  K+P     +I S+   VE    +     C ++  G P   +EW  NG  +  
Sbjct: 576  TFQLDVQPKKPKGTAPEIVSELRPVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKD 633

Query: 4019 KNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLP 4078
              R       G V +       +D G+Y C   N  G  E+K  +K        + ++L 
Sbjct: 634  SRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIAFARPEFRTKL- 692

Query: 4079 KHMKSIE 4085
            K +K++E
Sbjct: 693  KPVKAVE 699



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 35/113 (30%), Positives = 52/113 (46%), Gaps = 3/113 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-S 695
           P+    L+ V+A+ G ++ F+ RI   G P  K+EW K    IE   RFT       + S
Sbjct: 395 PEIEDSLRDVSALPGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEVFS 452

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ 748
           L +  L   D+G Y C A +  G AE+ A L V       R  +  E+   ++
Sbjct: 453 LIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEELIGPRFEKMKESFTVVE 505



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+    L  +E  EG +  L C +   G     +EW  NG  +K   R +       V 
Sbjct: 590  APEIVSELRPVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVK 647

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            L + +   +D G YTC   N+LG A +   L+VIA
Sbjct: 648  LTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIA 682



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 44/147 (29%), Positives = 69/147 (46%), Gaps = 13/147 (8%)

Query: 1528 DEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTD--MVDEVTTQAPICTTSLK 1585
            D  +C LT R       +T ++ G+ ++ +  +      T   +V+EV ++ PI    LK
Sbjct: 1425 DGETCSLTIRD------ATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSR-PIFQQKLK 1477

Query: 1586 NVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT--ETNNFGFVALDIMSCL 1643
             V   EG+   FE +L  +   T  VEW+ ++  +  G RFT  E  N G   L I    
Sbjct: 1478 AVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTN 1535

Query: 1644 PEDSGTYTCRAINALGEAVTSGIAIVH 1670
             ED+GTY   A N LG+  +  +  V+
Sbjct: 1536 IEDAGTYKVVAYNNLGKVTSQALLRVN 1562



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 2/106 (1%)

Query: 1968 VQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK 2027
            VQ    +   P     + + EV EG  V LE T++    P   +EWY +G       R  
Sbjct: 1658 VQKKKVIGNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVM 1715

Query: 2028 TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
            TT+D    ++    A   D G Y C ATN +G A +++ + V   S
Sbjct: 1716 TTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPS 1761



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 1/95 (1%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            PQFI  +  V  +  G  +++  +E  G P  +IEW  N + I A+SR    F     ++
Sbjct: 2157 PQFIGDVPGVVELVQGD-NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATI 2215

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
             + ++ + DSG Y C+AV+  G    +  ++V P+
Sbjct: 2216 ALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK 2250



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P  +  L+ + E++EG  A  E  ++    PT+  EWY+DG  +  S R+ S    G   
Sbjct: 2257 PNIVSGLKSV-EVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIAR 2313

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            L I    AED G+Y  +  N LG   ++A + +
Sbjct: 2314 LVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 36/99 (36%), Positives = 47/99 (47%), Gaps = 5/99 (5%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIFNFG 826
            RP+F   L  + E+ EG  A FE ++     P   VEWY     I    R  I S+   G
Sbjct: 2351 RPEFKEKLTKV-EVTEGDRAKFEVRVKGYPYP--EVEWYHGSNRILDEDRFEIESVKETG 2407

Query: 827  YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            Y SL +  +  EDAG Y   AVNK G++   A + V  R
Sbjct: 2408 YYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 5/106 (4%)

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
            +A K + I+   P+F  Q++     +    RFEC+V    +P+  I W ++GK L     
Sbjct: 3131 EAKKSKGII---PEFFRQLRRVEAVQGSTARFECKVSGHPEPQ--IAWLKDGKELAIPRY 3185

Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             +  YD     L       ED G+Y C A N+ GE  + A++   K
Sbjct: 3186 IKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASLVLSK 3231



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+F  Q++ V + V+G +A FE ++     P+ ++ W  +GK+L      + F+D  +  
Sbjct: 3140 PEFFRQLRRV-EAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCK 3196

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            L       E+ G+Y CVA+N+ G  S+ A+L
Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL 3227



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV-A 1769
            P F   +K+I+V E   A F  R+   G+P+ +VEW + G  I++  R ++     +   
Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            L +  V  ED GTY C A N+ G+   S  L V+ +
Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 3/106 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F   LH+ E VEG  + LECR++        VEW  +G+  K  +     ++  +  
Sbjct: 3430 APLFIAPLHDQEVVEGETIRLECRVR--ATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCT 3487

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
            L +     ED G Y C A N+ G    S A   + +  +I    HP
Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRG-RSVAQLTVKEALIIPHFDHP 3532



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 6/123 (4%)

Query: 1026 ASRYSKRTEEEVKITQKPRFLGP----LKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081
            A+  +   E   ++T     +GP    +K +  +VEG+S    ARV  +      +EW  
Sbjct: 470  ATNEAGEAESMAQLTVNEELIGPRFEKMKESFTVVEGESVELVARVTGKP--APEIEWTK 527

Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
            +GK +   N + T        L I     +DSG+Y   ARN +G A ++  + V+ +   
Sbjct: 528  DGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPK 587

Query: 1142 DTS 1144
             T+
Sbjct: 588  GTA 590



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 4/121 (3%)

Query: 1954 KIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW 2013
            K Q   D  R   +   +  V  +P+F + +   EVTEG     E  +     P   VEW
Sbjct: 2328 KCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGY--PYPEVEW 2385

Query: 2014 YCNGRPVQQGHRFK--TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
            Y     +    RF+  +  + GY +L +     ED G Y C A N  G++   + ++V+ 
Sbjct: 2386 YHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNE 2445

Query: 2072 K 2072
            +
Sbjct: 2446 R 2446



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 4/107 (3%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR-ITSIFNFGY 827
            RP+ +  LQD+ +   G  A F+ +++    P   V+WY+    IT     I      GY
Sbjct: 2646 RPRILEKLQDV-DSSVGERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGY 2702

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874
             SL I ++  ED G+Y    +N  GE  STA +R+A      + +GI
Sbjct: 2703 FSLTIEYIDYEDEGAYKAVVINDSGEVSSTAVLRLAEGMIEPSFIGI 2749



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 33/121 (27%), Positives = 52/121 (42%), Gaps = 13/121 (10%)

Query: 50   TQVESSGDRQPITAGRPGEPSP------------PIFEQIFKNARFAQGGNAKFEGKLRG 97
            TQ E  GD   + +   GE S             P F++  KN +  +G  A+F  +++G
Sbjct: 3202 TQPEDEGDYTCVASNEAGEASSHASLVLSKPLVMPEFKERLKNIKVVEGDEAQFSVRVKG 3261

Query: 98   NPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC 157
             P P V W +    +    ++S +  E+    +L I  +   D G Y C A N  G+  C
Sbjct: 3262 EPEPKVEWFKTGKKIKSHARFSSKAGEK-HTYTLTISDVAMEDFGTYKCVASNDAGKVQC 3320

Query: 158  S 158
            S
Sbjct: 3321 S 3321



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 3/89 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SLD 2834
            F   L NI   EGD   F   V+   +P  K+EWF   K + S  R+ S     +  +L 
Sbjct: 3238 FKERLKNIKVVEGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKHTYTLT 3295

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I+    ED G Y C A+N  G    SG L
Sbjct: 3296 ISDVAMEDFGTYKCVASNDAGKVQCSGRL 3324



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 53/197 (26%), Positives = 85/197 (43%), Gaps = 38/197 (19%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            +EWLK+G  V+ S R       G V LTIK+    D G YTC   N +G A +   L ++
Sbjct: 622  IEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVI 681

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPR-FLGPLKGTNKIVEGQSA 1061
                  A  +    L+ ++ +E      +  + +VK+   P+  +   +GT  IVE  S 
Sbjct: 682  A----FARPEFRTKLKPVKAVE-----GEEVQLDVKVEGYPKPDIEWYRGTTMIVE--SG 730

Query: 1062 HFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVAR 1121
             F+   E + D                          G  +L I+ ++ +D+G   VVA 
Sbjct: 731  RFKVMEEEEED--------------------------GLYSLVISKLQLDDTGTIKVVAT 764

Query: 1122 NAAGEAQLSASMTVETR 1138
            NA+G+A   A + V+ R
Sbjct: 765  NASGKATSRADLEVKER 781



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 58/213 (27%), Positives = 83/213 (38%), Gaps = 27/213 (12%)

Query: 2523 GQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRF-RTTHDFGFVTLDINSVVANDAGLY 2581
            G+ A +  RV          +W+ + V L    RF     D G  +L I+ V   D G Y
Sbjct: 997  GEEAEFSIRV----SGRAEVDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTY 1052

Query: 2582 MCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQA 2641
             C   N +G               I +  + PE  +       A   VP   ++     A
Sbjct: 1053 KCLVFNESGKVTTRAKLC------IKEAIVAPEEVD-------AAETVP---IEGS---A 1093

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P  T  L+S + + EG+   LE  V     P   +EW K+ V L T  RLK   D  +  
Sbjct: 1094 PKITKPLESVE-VNEGEDFDLECVVSGSPSPT--VEWTKDLVKLRTSYRLKEKLDGNVAK 1150

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            L     R +D G Y C   N  G+A +T  +K+
Sbjct: 1151 LVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 9/131 (6%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566
            +P F ++   P E+ EG  A +E RV   G P L+ EW+    +++   R+  T D    
Sbjct: 1188 RPEF-KIKMSPVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244

Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAM 2626
            T+ I +V   DAG Y C A N AG               + ++   PE   +    ++ +
Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAG------KTTSRADLTVKEREFAPEFETRDDTIDSEV 1298

Query: 2627 NKVPEMFVDTG 2637
            NK  E+ V TG
Sbjct: 1299 NKEVEIKVTTG 1309



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+F  ++  V ++ EG  A FE R+     P L+VEWF    K+    RY    D     
Sbjct: 1189 PEFKIKMSPV-EVTEGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDSGRYTFTADKNRYT 1245

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            + I     E++G Y CVATN  G+ +++A+L    +E
Sbjct: 1246 MVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKERE 1282



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P     +K + V E + A  E   +  G P   +EW R+G+ ++ S R+ +  + G   L
Sbjct: 2257 PNIVSGLKSVEVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVRSTLENGIARL 2314

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTL 1800
             +     ED GTY C+  N+LG   TS+ L
Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTSAHL 2344



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 40/130 (30%), Positives = 61/130 (46%), Gaps = 15/130 (11%)

Query: 2907 EYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            E PKP    P   +       +EG+ + +E +V  K +P   I W  +G V    +R K 
Sbjct: 2542 EVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKT 2599

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022
              D    TL + DV   D GIY C A N  G A +S+ +       ++ER   P+    L
Sbjct: 2600 YFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAEL------TVLEREARPR---IL 2650

Query: 3023 EKIQNLEDSL 3032
            EK+Q+++ S+
Sbjct: 2651 EKLQDVDSSV 2660



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 4/102 (3%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            + IE +KP  P F   + D  +V EG  +  +CRV     P   ++W  +GR F     +
Sbjct: 3422 VVIESKKP-APLFIAPLHDQ-EVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHI 3477

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +T  D     L I      D G Y C A NK G   + A++T
Sbjct: 3478 YTEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLT 3519



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP+F   L   + +VEG+ + LE +V  R  P   +EW K+G T      + + FD    
Sbjct: 3430 APLFIAPLHDQE-VVEGETIRLECRV--RATPRPMVEWKKDGRTFKEDYHIYTEFDGQHC 3486

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            TL I   + +D G Y C A N  G   S A + +++
Sbjct: 3487 TLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKE 3522



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 2/94 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P FI  +    V E E +R ECRV  +  P+  +EW ++G+     +   T +D    +L
Sbjct: 3431 PLFIAPLHDQEVVEGETIRLECRV--RATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCTL 3488

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             I     ED G Y C A N  G   + A ++ K+
Sbjct: 3489 VIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKE 3522



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 5/87 (5%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFG 2432
            RP+F Q L+ +  I EG++  F+ +L  +  PT  VEWF++   I D  R  IT+  + G
Sbjct: 1469 RPIFQQKLKAVSTI-EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSG 1525

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459
               + I     ED G Y   A N LG+
Sbjct: 1526 VYVLVIEDTNIEDAGTYKVVAYNNLGK 1552



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 2/86 (2%)

Query: 781  ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
            E++EG     E  ++    P   +EWYKDG   TA+ R+ + F+    S+     +  D 
Sbjct: 1678 EVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDD 1735

Query: 841  GSYTVRAVNKLGEAISTASIRVAARS 866
            G Y   A N LG A S+A + V   S
Sbjct: 1736 GEYKCVATNPLGSAQSSARLTVTVPS 1761



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 4/97 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS-TFDFGLV 2700
            P F   LK+  K+VEG       +V+   +P  K+EWFK G  + + AR  S   +    
Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            TL+I+ +  +D G Y C A+N  G+   +  + +++R
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 10/88 (11%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT----FHDF 3337
            P+F  +++++ K+VEG  A F  R+    +P+ KVEWF  GKK+    R+ +     H +
Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGR 3365
             + I D+     E+ G Y+CVA+N  G+
Sbjct: 3293 TLTISDVAM---EDFGTYKCVASNDAGK 3317



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ--TG 127
            SPP F++  K      G   K    + G+PTPV+ W +    ++E  +     +++    
Sbjct: 4203 SPPRFQEELKGVITVVGTTTKLSVPIIGHPTPVIEWYKDDREVLEGGRIRFEQDQEGRFT 4262

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
             VSL I+ +   DEG Y C A+N+ G    S  ++
Sbjct: 4263 IVSLTIRDVRLTDEGRYKCVAKNKSGTDFSSATVK 4297



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 2/84 (2%)

Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
           EG  +    ++T    PT  +EW K   P+T S R+ + F     +L I   R  DAG+Y
Sbjct: 312 EGEESKLVCKVTGKPAPT--IEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTY 369

Query: 844 TVRAVNKLGEAISTASIRVAARST 867
            V A N  G A S A ++V  RST
Sbjct: 370 KVVARNDSGTAHSIAELQVQERST 393



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 51/192 (26%), Positives = 78/192 (40%), Gaps = 21/192 (10%)

Query: 2011 VEWYCNGRPVQQGHRF-KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            V+W+ +   +    RF     D G  +L I     ED GTY C   N  G+  T + + +
Sbjct: 1012 VDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI 1071

Query: 2070 DAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHF 2129
                        ++ +   +E++  E   PIE    G  P     L S+E + EG+    
Sbjct: 1072 ------------KEAIVAPEEVDAAETV-PIE----GSAPKITKPLESVE-VNEGEDFDL 1113

Query: 2130 ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNK 2189
            EC V     P  T++W  +  K+R  +R +   D     L       ED G Y C   N+
Sbjct: 1114 ECVVS--GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINE 1171

Query: 2190 LGEAVNTCTLKV 2201
             G+A  T  +KV
Sbjct: 1172 HGKASTTGEVKV 1183



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 3/106 (2%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            ST  EV+   +S P F  ++     V EG  A FE +VE    P L++E++     ++ +
Sbjct: 1176 STTGEVKVNVLSRPEFKIKM-SPVEVTEGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDS 1232

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             R+  T D    ++ I +   EDAG Y   A N  G  TS   +TV
Sbjct: 1233 GRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 3/93 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P   + LKS + + EG+   LE  V     P L  EW+++G+ +    R++ST + G+  
Sbjct: 2257 PNIVSGLKSVE-VKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIAR 2313

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            L I     +D G Y C+  N LG   ++A + I
Sbjct: 2314 LVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P+F R L+ + E  +G  A FE +++   +P  ++ W KDG+ +     I   ++     
Sbjct: 3140 PEFFRQLRRV-EAVQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYIKPFYDGEVCK 3196

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            L     + ED G YT  A N+ GEA S AS+
Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL 3227



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 4/97 (4%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT-SNDFGFA 1902
            P F  +L    K+ EG  A +  R++  P+P  +VEW+  GK ++S  R+ + + +    
Sbjct: 3236 PEFKERLKN-IKVVEGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
             L I  V  ED G Y C A N+ G+   S RL+V+ +
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 3/104 (2%)

Query: 3410 TSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRF 3469
            T V E K  AP+F  PL + E + EGE    E R+  T  P   VEW  +G++ K     
Sbjct: 3421 TVVIESKKPAPLFIAPLHDQEVV-EGETIRLECRVRATPRP--MVEWKKDGRTFKEDYHI 3477

Query: 3470 RTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             T  D     L I     ED G Y C A N  G   + A + V+
Sbjct: 3478 YTEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK 3521



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 34/99 (34%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 764  EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
            E     P FI PL D  E+ EG     E ++   + P   VEW KDGR       I + F
Sbjct: 3425 ESKKPAPLFIAPLHDQ-EVVEGETIRLECRVR--ATPRPMVEWKKDGRTFKEDYHIYTEF 3481

Query: 824  NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +  + +L I   + ED G+Y   A NK G   S A + V
Sbjct: 3482 DGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV 3520



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            ++PQ  +P++  +V E     L  T++    PT   EWY +   V++  R K+    G  
Sbjct: 7    DRPQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             L I    AED G Y C   N  G A + + + V
Sbjct: 65   TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 31/94 (32%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+ +  L G   + E ++A   C I   P PN   EWY +   ++   R ++    G A 
Sbjct: 9    PQILQPLEG-VDVKEDENAILSCTISGTPTPN--AEWYRDSIRVRESRRIKSEVVNGMAT 65

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            L I     ED GEY C   N  G A S   LNV+
Sbjct: 66   LTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP     ++ +   E   A     +   G P   +EWL+NG+ ++ S R       G V 
Sbjct: 590  APEIVSELRPVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVK 647

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            L +K    +D G YTC   NELG A + + L V
Sbjct: 648  LTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+ ++ L ++E  EG +  LEC +   G  +  VEW  +   ++T +R +   + +   
Sbjct: 1093 APKITKPLESVEVNEGEDFDLECVVS--GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAK 1150

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L      PED G Y C   N+ G+A T+  ++V
Sbjct: 1151 LVFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 8/142 (5%)

Query: 1024 EDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNG 1083
            E  S+     EEE+ I   P+F+G + G  ++V+G +  ++  +E +      +EWY N 
Sbjct: 2141 EVTSKGYLHVEEELTI---PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNE 2195

Query: 1084 KQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
            + I + +R+Q         + + +V  +DSG+Y   A N AG      ++ V+ +    T
Sbjct: 2196 RLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGT 2255

Query: 1144 S-SIHRGLYEKTRHIEESKFVE 1164
              +I  GL  K+  ++E +  E
Sbjct: 2256 EPNIVSGL--KSVEVKEGEQAE 2275



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 2/96 (2%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   +    +LV+G +  L  +V  R  P  +IEW+ N   +   +R++ +F     T
Sbjct: 2157 PQFIGDVPGVVELVQGDNYDLSLEV--RGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            +++ ++  DDSG+Y CKA N  G      +I ++ +
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK 2250



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 5/96 (5%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFFNFG 965
            +PEFK  +  ++ + EG  A FE R++  G     VEW      +    R  I +    G
Sbjct: 2351 RPEFKEKLT-KVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETG 2407

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            Y +LT+  V   DAG Y C A N  G++T  A+L +
Sbjct: 2408 YYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEV 2443



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 4/97 (4%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT--SIFRFGYI 694
            P+F   L  V   EG +  FE R++  G P  ++EW      I    RF   S+   GY 
Sbjct: 2352 PEFKEKLTKVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETGYY 2409

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            SL +  +  +D+G Y C AV+  G +  +A L V  R
Sbjct: 2410 SLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 10/141 (7%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P     ++ +   E +A   E R+   G P+  + WL++G+     NR+ T  D    
Sbjct: 2549 EEPTILQRLQPVDTIEGEAIKMECRVS--GKPEPTITWLKDGLVFLTDNRIKTYFDGDVC 2606

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L ++ V   D G Y C A N  G A +S+ L V     L+ E++    L+K+Q ++ S 
Sbjct: 2607 TLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTV-----LEREAR-PRILEKLQDVDSS- 2659

Query: 1829 RYQRREDVEVAVNQAPRFITQ 1849
                R   ++ V+ +P  + Q
Sbjct: 2660 -VGERAMFKIRVSGSPMPVVQ 2679



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 4/91 (4%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-S 695
            P+F   L+ V A++G    FE ++   G P  +I WLK+G+ + A  R+   F  G +  
Sbjct: 3140 PEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKEL-AIPRYIKPFYDGEVCK 3196

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVL 726
            L       +D G+YTC A +  G A + A L
Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL 3227



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-TETNNFGFVALDIMSC 1642
            LKN+++ EG  A F  R+    +   KVEW+   K +KS +RF ++        L I   
Sbjct: 3242 LKNIKVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYTLTISDV 3299

Query: 1643 LPEDSGTYTCRAINALGEAVTSG 1665
              ED GTY C A N  G+   SG
Sbjct: 3300 AMEDFGTYKCVASNDAGKVQCSG 3322



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 40/150 (26%), Positives = 68/150 (45%), Gaps = 12/150 (8%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G RP  L  L  ++ +KE + A   C +     P+   +W+ +  ++R   R ++    G
Sbjct: 6    GDRPQILQPLEGVD-VKEDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSEVVNG 62

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225
               L I  T AED G Y C   N+ G A +   L      N+ +  + P+   K++ ++A
Sbjct: 63   MATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPL------NVRVPVK-PSFTSKMKPVDA 115

Query: 2226 -QGHSTRIEVEEPKISPPRFVTELRGTTHV 2254
             +G   R +V   K SP   V   +G+T +
Sbjct: 116  EEGQEVRFDV-HVKGSPKPDVVWYKGSTMI 144



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 57/213 (26%), Positives = 84/213 (39%), Gaps = 40/213 (18%)

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
            EG+   L C++   G P   +EW      VT   R +T ++     L I      D G Y
Sbjct: 312  EGEESKLVCKVT--GKPAPTIEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTY 369

Query: 1251 TVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA 1310
             V A N                     D+    +I ++Q+ E   R TK           
Sbjct: 370  KVVARN---------------------DSGTAHSIAELQVQE---RSTK----------- 394

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV-A 1369
            P+   +L ++  + G  V  + R+   G    +VEW      I+ G RF  A E D V +
Sbjct: 395  PEIEDSLRDVSALPGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEVFS 452

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L +  +   D+G Y C ATN+ GEA +   L V
Sbjct: 453  LIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 61/252 (24%), Positives = 94/252 (37%), Gaps = 14/252 (5%)

Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRT 3099
            ++ G  P F    K +  I EG+   +E  L  +      +EWF +   I    R  I  
Sbjct: 1464 NEVGSRPIFQQKLKAVSTI-EGESTRFEVKL--SAMPRPTVEWFKSSSQIYDGGRFTITE 1520

Query: 3100 VYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159
                G+ VL I  T   D+GTY   A N  G+      L   +      P F   +   E
Sbjct: 1521 EENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLT--VPEF---MDKAE 1575

Query: 3160 G-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
            G ++  +    E TV     P  ++EW+   + +  S+RI   S      + ++     D
Sbjct: 1576 GPIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDD 1635

Query: 3219 SGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPS 3278
            SG Y C A NK G       ++   K  +      PD +  +   E  +G       T S
Sbjct: 1636 SGMYQCVARNKAGSSSRTFNLDVQKKKVI---GNAPDIITHLISKEVKEGGTVTLECTVS 1692

Query: 3279 AEPPKFITQIQD 3290
             +P   I   +D
Sbjct: 1693 GKPAPNIEWYKD 1704



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 34/99 (34%), Positives = 47/99 (47%), Gaps = 5/99 (5%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--F 1232
            S+P+F Q L     + EG++   E +L  M  PT  VEWF +   +  G RF    +   
Sbjct: 1468 SRPIFQQKLKAVSTI-EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENS 1524

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            G   L I      D G Y V A N+LG   + A++RV E
Sbjct: 1525 GVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNE 1563



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P  I  L S    EGG +  E  +   G P   IEW K+G    A+ R  + F     S+
Sbjct: 1668 PDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASV 1725

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
                    D GEY C A +  G A++ A L VT
Sbjct: 1726 TFTDAQGFDDGEYKCVATNPLGSAQSSARLTVT 1758



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 36/116 (31%), Positives = 58/116 (50%), Gaps = 10/116 (8%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            + E   P++I  +    +LV+G    L   +E +  P  +IEWY N +++   SR +L+ 
Sbjct: 2151 EEELTIPQFIGDVPGVVELVQGDNYDLS--LEVRGTPRPEIEWYHNERLIYATSRVQLSF 2208

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTE 3020
                 T+ L +V   DSG+Y CKA N  G   T S  +     N+  + + P+GTE
Sbjct: 2209 ISSKATIALYNVTLDDSGLYRCKAVNTAG---TGSKQF-----NINVQPKRPEGTE 2256



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 10/150 (6%)

Query: 993  ATTSANLTIVTKKDIIA---ESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ----KPRF 1045
            AT+   L+ ++ K  IA    +    GL + + +  A   SK+    V+  +    +P  
Sbjct: 2200 ATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNI 2259

Query: 1046 LGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDI 1105
            +  LK   ++ EG+ A  E  V      T T+EWY +G ++  + R+++  + G   L I
Sbjct: 2260 VSGLKSV-EVKEGEQAELEFVVSGTP--TPTLEWYRDGLRVKESRRVRSTLENGIARLVI 2316

Query: 1106 ASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
                AED G Y    RN  G    SA + +
Sbjct: 2317 TETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 11/128 (8%)

Query: 1417 GLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL 1476
            G  K Q   D  R   +  ++  V  +P F  +   +E V EG    FE +++       
Sbjct: 2325 GTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVE-VTEGDRAKFEVRVKGYPYP-- 2381

Query: 1477 KVEWFKNGQPVTIGHRFR--PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            +VEW+     +    RF    + + GY +L + +++ ED+G+Y C AVN  G      + 
Sbjct: 2382 EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAG------KS 2435

Query: 1535 TCRSTTDI 1542
            TCR+  ++
Sbjct: 2436 TCRADLEV 2443



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 28/88 (31%), Positives = 37/88 (42%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L  +   +G    FEC V    +P  +I W  + K L      K  +D     L  
Sbjct: 3142 FFRQLRRVEAVQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYIKPFYDGEVCKLTF 3199

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
              T  ED G YTC A+N  G A++  SL
Sbjct: 3200 YETQPEDEGDYTCVASNEAGEASSHASL 3227



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 32/92 (34%), Positives = 45/92 (48%), Gaps = 6/92 (6%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDA-TLKVEWYHNNKPLKSGSRFT--ETNNFGFVALDIM 1640
            ++++++ EG RA F    + VS     KVEW   ++ L++G R +  E        L I 
Sbjct: 3533 IQDLDVIEGDRAKFH---VEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTIT 3589

Query: 1641 SCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            +C P DSG YTC A N  GE    G   V  K
Sbjct: 3590 NCKPTDSGKYTCIARNKAGENTCHGRLAVKEK 3621



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 3/88 (3%)

Query: 264  SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            +P K+ Q         G        +SGNP P  TWF+  + L +  +  I TT + ++L
Sbjct: 5964 APAKVDQAATPGSGVVGGKITLTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSL 6023

Query: 324  RVRNTQKSDSGHYTLLAENPNG---CIV 348
             +   Q  D G Y L+ +N  G   C+V
Sbjct: 6024 TIERIQFRDEGEYELVVKNDGGEDSCVV 6051



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 66/262 (25%), Positives = 100/262 (38%), Gaps = 34/262 (12%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY- 2158
            + E + G  PV    L  +  +  G+ A F  RV         +DWF +   +    R+ 
Sbjct: 974  VNEVEKGVGPVIEEKLKDV-TVMPGEEAEFSIRVSG----RAEVDWFKDEVMLNDEGRFI 1028

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLE 2218
                D G  +L I     ED GTY C   N+ G+      L +   +  I+  +  +  E
Sbjct: 1029 MEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI---KEAIVAPEEVDAAE 1085

Query: 2219 KIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEF 2278
             +           IE   PKI+ P    E+       EG+    EC V     P+  +E+
Sbjct: 1086 TVP----------IEGSAPKITKPLESVEVN------EGEDFDLECVVSG--SPSPTVEW 1127

Query: 2279 YHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKG 2338
              +   L+++ R     D     L  +   PED GEY    IN  G      S T   K 
Sbjct: 1128 TKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKA----STTGEVKV 1183

Query: 2339 SIISESQRPEGLEKIRELESAE 2360
            +++S   RPE   K+  +E  E
Sbjct: 1184 NVLS---RPEFKIKMSPVEVTE 1202



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 34/102 (33%), Positives = 47/102 (46%), Gaps = 5/102 (4%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--IT 959
            V E   +P F+  +K  +S  EG    FE +L  +   T  VEW K    +    R  IT
Sbjct: 1463 VNEVGSRPIFQQKLK-AVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTIT 1519

Query: 960  TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
               N G   L I+   + DAG Y   AYN +G+ T+ A L +
Sbjct: 1520 EEENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV 1561



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 34/125 (27%), Positives = 61/125 (48%), Gaps = 3/125 (2%)

Query: 3828 TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887
            T P+FI  +    VE  +G  ++  +E +  P+  IEWY N +L+ +  R +  +     
Sbjct: 2155 TIPQFIGDVPG-VVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKA 2213

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK-KLPDIILQNQVPRGMKRSEALTQM 3946
            ++ +  V  +DSG Y C+AVN  G    +  I+ + K P+    N +  G+K  E     
Sbjct: 2214 TIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPN-IVSGLKSVEVKEGE 2272

Query: 3947 EATIK 3951
            +A ++
Sbjct: 2273 QAELE 2277



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+  + L   E  EG++  L CR+   G  T  +EW+ +  P+K   R    +  D   
Sbjct: 2846 APEIVQRLKACEVPEGSSFKLRCRV--TGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
            L+ L     D G Y   A N LG   TS  L
Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAEL 2934



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 5/139 (3%)

Query: 2102 EEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTT 2161
            ++  G  P F   L  +E + +G  A FEC+V    +P +   W  +G+++      +  
Sbjct: 3133 KKSKGIIPEFFRQLRRVEAV-QGSTARFECKVSGHPEPQIA--WLKDGKELAIPRYIKPF 3189

Query: 2162 HDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIR 2221
            +D     L    T  ED G Y C A+N+ GEA +  +L ++    +    +    ++ + 
Sbjct: 3190 YDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASLVLSKPLVMPEFKERLKNIKVVE 3249

Query: 2222 QLEAQGHSTRIEVE-EPKI 2239
              EAQ  S R++ E EPK+
Sbjct: 3250 GDEAQ-FSVRVKGEPEPKV 3267



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L+   + V+G +A FE +V    +    + W  +GK++     I+ ++D     
Sbjct: 3140 PEFFRQLRRV-EAVQGSTARFECKVSGHPE--PQIAWLKDGKELAIPRYIKPFYDGEVCK 3196

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            L     + ED G YT VA N AGEA   AS+ +
Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASLVL 3229



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 4/97 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYV 1768
            P F  P++D+ V E   A F   +   G P  +VEWL+    +    R++   D      
Sbjct: 3527 PHFDHPIQDLDVIEGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSLEEDRETQMY 3584

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             L +    P DSG YTC A N+ GE      L V+ K
Sbjct: 3585 FLTITNCKPTDSGKYTCIARNKAGENTCHGRLAVKEK 3621



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 4/137 (2%)

Query: 1689 NQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748
            N+  +     + +  +E+I   P F    +   V E ++    AR+   G P   +EW +
Sbjct: 472  NEAGEAESMAQLTVNEELI--GPRFEKMKESFTVVEGESVELVARV--TGKPAPEIEWTK 527

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
            +G  +  +N + T        L ++  + +DSG Y C A N+ G A  +  L VQ K   
Sbjct: 528  DGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPK 587

Query: 1809 QLESQHESALQKIQQLE 1825
                +  S L+ ++  E
Sbjct: 588  GTAPEIVSELRPVEATE 604



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 51/168 (30%), Positives = 76/168 (45%), Gaps = 17/168 (10%)

Query: 1131 ASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQP--LSNPPP 1188
            A +T+E  S  D+     GLY  T    +S   +  +Q++ +   KP    P  +S   P
Sbjct: 547  AVLTIEESSRDDS-----GLYRCTAR-NKSGTADMTFQLD-VQPKKPKGTAPEIVSELRP 599

Query: 1189 V--SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSAD 1246
            V  +EG +  L C +   G P   +EW  NG  V    R K     G V L I    + D
Sbjct: 600  VEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADD 657

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVI--ERSDIVTDTQNEQAI--EQIQL 1290
             G+YT    N LGSA +   ++VI   R +  T  +  +A+  E++QL
Sbjct: 658  QGDYTCIVRNELGSAESKTKLKVIAFARPEFRTKLKPVKAVEGEEVQL 705



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 61/233 (26%), Positives = 93/233 (39%), Gaps = 30/233 (12%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTFFNFGYV 967
            P  +  +KD +++  G  A F  R+         V+W KD   +    R I    + G  
Sbjct: 983  PVIEEKLKD-VTVMPGEEAEFSIRVS----GRAEVDWFKDEVMLNDEGRFIMEGGDNGRF 1037

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
            +LTI  V   D G Y C  +N  G+ TT A L I  K+ I+A  +            DA+
Sbjct: 1038 SLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI--KEAIVAPEE-----------VDAA 1084

Query: 1028 RYSKRTEEEVKIT-QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
                   E V I    P+   PL+   ++ EG+    E  V      + TVEW  +  ++
Sbjct: 1085 -------ETVPIEGSAPKITKPLESV-EVNEGEDFDLECVV--SGSPSPTVEWTKDLVKL 1134

Query: 1087 TSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139
             ++ R++   D     L     R ED G Y     N  G+A  +  + V   S
Sbjct: 1135 RTSYRLKEKLDGNVAKLVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLS 1187



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 6/92 (6%)

Query: 66   PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            P E S P   +  ++    +G +   E  + G+P+P V WT+    L    + S R  E+
Sbjct: 1088 PIEGSAPKITKPLESVEVNEGEDFDLECVVSGSPSPTVEWTKDLVKL----RTSYRLKEK 1143

Query: 126  -TGDVS-LLIKQIGPGDEGEYTCTARNQYGEA 155
              G+V+ L+ KQ  P D GEY CT  N++G+A
Sbjct: 1144 LDGNVAKLVFKQARPEDIGEYKCTVINEHGKA 1175



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 3/116 (2%)

Query: 750  LEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKD 809
            + ++ K      ++     RP+F   +  + E+ EG  A FE ++     P ++VEW+K 
Sbjct: 1169 INEHGKASTTGEVKVNVLSRPEFKIKMSPV-EVTEGSEAAFEVRVEGF--PKLQVEWFKG 1225

Query: 810  GRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
               I  S R T   +    ++ I ++  EDAG Y   A N  G+  S A + V  R
Sbjct: 1226 MTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKER 1281



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 60/218 (27%), Positives = 84/218 (38%), Gaps = 38/218 (17%)

Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLC 3495
            E      ++T   +P  +V WY +GK      R           L+I+    EDSG Y C
Sbjct: 2465 EGGETTLKVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKC 2524

Query: 3496 RAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESG 3555
             A N  G A  + +++V        E   P G E TI  +  L+     VDT+  EA   
Sbjct: 2525 EARNKLGFADKSFTIRV--------EVPKPTGEEPTI--LQRLQ----PVDTIEGEA--- 2567

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
                                  ECR+    + +  + W  +G   LT +R+KT  D    
Sbjct: 2568 -------------------IKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVC 2606

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
             L I  V   D G+Y C A N  G A  S +L V  R+
Sbjct: 2607 TLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLERE 2644



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 6/129 (4%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            +E ++ K   P F  +LR    V +G TA FEC+V    +P  +I +  +GK L      
Sbjct: 3130 VEAKKSKGIIPEFFRQLRRVEAV-QGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYI 3186

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
               +D     L      PED G+Y+  A N  G  +S  S+ V +K  ++ E +  E L+
Sbjct: 3187 KPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASL-VLSKPLVMPEFK--ERLK 3243

Query: 2352 KIRELESAE 2360
             I+ +E  E
Sbjct: 3244 NIKVVEGDE 3252



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 41/153 (26%), Positives = 67/153 (43%), Gaps = 4/153 (2%)

Query: 3362 KLGRDSTKANLKCTSKENLI-LDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAP 3420
            KL  DS K +++ + + N + + S  P        + +       R  D  V+  KG AP
Sbjct: 240  KLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFDVKVKAPKGDAP 299

Query: 3421 VFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVIL 3480
             FT+ L+++  + EGE +    ++T    P   +EW      +    R RT  +     L
Sbjct: 300  SFTIDLTHVRAI-EGEESKLVCKVTGKPAP--TIEWLKGELPVTTSLRVRTDFEKNVATL 356

Query: 3481 EISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             I  T   D+G Y   A N+ G A + A ++VQ
Sbjct: 357  VIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQ 389



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 2/98 (2%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V+  P+F   +  +E  EG+    E R++  G   ++VEWF     I+   R+    +
Sbjct: 1183 VNVLSRPEFKIKMSPVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTAD 1240

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +   + + +V  ED+G Y C ATN  G+  +   L V
Sbjct: 1241 KNRYTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTV 1278



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 32/161 (19%)

Query: 2576 NDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVD 2635
            +DAG+Y C+A N AG                        SWE +++K++A    P+    
Sbjct: 1337 SDAGVYKCQATNAAGSAS--------------------RSWE-VKVKQSA----PKT--- 1368

Query: 2636 TGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF 2695
            TG  + PI    L++ + + EG    L  +V     P   I+W ++GV +   +R+K  F
Sbjct: 1369 TG--EEPIIIRKLQAQE-IDEGSTANLVCKVTA-AKPEPSIKWTRDGVKIRENSRIKMVF 1424

Query: 2696 DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            D    +L+I     DD G+Y    TN  G A ST  + + +
Sbjct: 1425 DGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNE 1465



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 5/108 (4%)

Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG--HRF 1359
            R  +TV   P+F + L  +E VEG+    + R++        VEW+     I     H+ 
Sbjct: 1754 RLTVTVPSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQI 1811

Query: 1360 RPAYEFDYV-ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
               YE D   +L +L+   ED+ +Y C A N+ G+      L VI K+
Sbjct: 1812 TEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEKQ 1859



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 41/137 (29%), Positives = 61/137 (44%), Gaps = 13/137 (9%)

Query: 1567 TDMVDEVTTQA---PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN-NKPLKS 1622
            T  V  + TQ    PI    +KNVE + G+   FE   I V    +    +H  ++ +  
Sbjct: 2046 TTTVQVIVTQRSIRPIFGQKMKNVEGRIGEDVRFE---IQVEGTPVPAVTFHRESEQIYD 2102

Query: 1623 GSRFT--ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQ 1680
            G R++  E  N G   L I +  PED+G Y C A+N  GE  + G   V  + +I    Q
Sbjct: 2103 GGRYSIVEEEN-GLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI---PQ 2158

Query: 1681 HEGALPRLNQLEDTSKY 1697
              G +P + +L     Y
Sbjct: 2159 FIGDVPGVVELVQGDNY 2175



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 4/100 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GFV 3478
            P+F   + N+E  R GE+  FE ++  T  P   V ++   + +  G R+    +  G  
Sbjct: 2060 PIFGQKMKNVEG-RIGEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLF 2116

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            +L I  T PED+GEY C A N  GE  +   + V+ +  I
Sbjct: 2117 VLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI 2156



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            +EE+ +  PQFI  +  + EL +G N  ++  L     P   +EWY + R I A+SR+  
Sbjct: 2150 VEEELTI-PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQL 2206

Query: 822  IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             F     ++ + ++  +D+G Y  +AVN  G      +I V
Sbjct: 2207 SFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV 2247



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 27/102 (26%), Positives = 54/102 (52%), Gaps = 5/102 (4%)

Query: 3279 AEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR--TFHD 3336
            A  P+F  ++  V ++ EG  A FE R+     P+  VEW++   ++    R+   +  +
Sbjct: 2349 ATRPEFKEKLTKV-EVTEGDRAKFEVRVKGYPYPE--VEWYHGSNRILDEDRFEIESVKE 2405

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
             G   L +    +E++G Y+C+A NK G+ + +A+L+   ++
Sbjct: 2406 TGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQ 2447



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 3/104 (2%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            + + T + P  ++ LQ +  + EG     E +++   +PT  + W KDG      +RI +
Sbjct: 2543 VPKPTGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKT 2599

Query: 822  IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
             F+    +L I  ++  D G Y   A N  G A S+A + V  R
Sbjct: 2600 YFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLER 2643



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 8/106 (7%)

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF 685
            P GEE      P  +  L+ V  +EG  I  E R+    +PT  I WLK+G      +R 
Sbjct: 2546 PTGEE------PTILQRLQPVDTIEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRI 2597

Query: 686  TSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
             + F     +L +  + + D G Y C A +++G A + A L V  R
Sbjct: 2598 KTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLER 2643



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 40/146 (27%), Positives = 68/146 (46%), Gaps = 8/146 (5%)

Query: 635  PPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            P P FI PL     +EG  I  E R+     P   +EW K+G++ +      + F   + 
Sbjct: 3429 PAPLFIAPLHDQEVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYTEFDGQHC 3486

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE-DY 753
            +L +    I+D G Y C A +  G   + A L V   A I     HP  +Q +  +E D 
Sbjct: 3487 TLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV-KEALIIPHFDHP--IQDLDVIEGDR 3543

Query: 754  SKYQHQESIEEQTSQRPQFIRPLQDL 779
            +K+ H E +  + + + ++++  Q+L
Sbjct: 3544 AKF-HVE-VSGKPAAKVEWLKGDQEL 3567



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 34/101 (33%), Positives = 48/101 (47%), Gaps = 5/101 (4%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP FI  L+   ++ EG++   ECR+   P P   VEW  +G+  +  +   T  D    
Sbjct: 3430 APLFIAPLHDQ-EVVEGETIRLECRVRATPRP--MVEWKKDGRTFKEDYHIYTEFDGQHC 3486

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
             L I     ED G Y C A N  G+  S  +L V  KE++I
Sbjct: 3487 TLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV--KEALI 3525



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F+ PL    ++VEG++   E RV  ++     VEW  +G+       I T  D  +  
Sbjct: 3431 PLFIAPLHD-QEVVEGETIRLECRV--RATPRPMVEWKKDGRTFKEDYHIYTEFDGQHCT 3487

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            L I   + ED G Y  +A+N  G  +  A +TV+
Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK 3521



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 3/104 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    P F+  +K+  ++ EG      AR+   G     +EW KDG+ V  ++ + T 
Sbjct: 485  VNEELIGPRFEK-MKESFTVVEGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTK 541

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
                   LTI+  +  D+G Y C A N  G A  +  L +  KK
Sbjct: 542  ERDDQAVLTIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKK 585



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 24/84 (28%), Positives = 51/84 (60%), Gaps = 6/84 (7%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSINSLRNDD 2711
            + EG  V ++ +V  + +PN  ++WFK+G  +  +T   +K   +   + + ++SL  +D
Sbjct: 797  VTEGNEVSIQLRV--KANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSL--ED 852

Query: 2712 SGIYTCKATNLLGEAVSTASIKIE 2735
            +G+Y C+A+N LG+A  +  +K++
Sbjct: 853  TGVYKCEASNRLGKASRSFDVKVQ 876



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 56/319 (17%), Positives = 121/319 (37%), Gaps = 13/319 (4%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            S P F+         +G  A FE ++ G P   V W +    + +  +Y+  +       
Sbjct: 1187 SRPEFKIKMSPVEVTEGSEAAFEVRVEGFPKLQVEWFKGMTKIEDSGRYT--FTADKNRY 1244

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVEH 188
            +++I  +   D G Y C A N  G+      +   E                 V++ VE 
Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKEREFAPEFETRDDTIDSEVNKEVEI 1304

Query: 189  KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES 248
            K   T G     S  T   A  +            D   Y+  +  +   S ++ +    
Sbjct: 1305 KV--TTGEPIRDSINTDVRAIGDSHTCFIVRAKLSDAGVYKC-QATNAAGSASRSW---- 1357

Query: 249  DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSG-NPRPRVTWFKNGQRLI 307
            +V++     ++ G    P I +K +  ++ EG+ A    +++   P P + W ++G ++ 
Sbjct: 1358 EVKVKQSAPKTTG--EEPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKIR 1415

Query: 308  NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
             +++ +++      +L +R+    D G Y +   N  G   ++  + V       +  Q+
Sbjct: 1416 ENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQK 1475

Query: 368  SQYITDTQQRETEERIEIS 386
             + ++  +   T   +++S
Sbjct: 1476 LKAVSTIEGESTRFEVKLS 1494



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 5/115 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD--FGYV 1768
            P+F   +K +   E ++  FE +L  +  P+  VEW ++   I    R T   +   G  
Sbjct: 1470 PIFQQKLKAVSTIEGESTRFEVKLSAM--PRPTVEWFKSSSQIYDGGRFTITEEENSGVY 1527

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL-QLESQHESALQKIQ 1822
             L ++  N ED+GTY   A N LG+  + + L V    ++ +   + E  ++K +
Sbjct: 1528 VLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEKTE 1582



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%)

Query: 69   PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
            PS P F+Q  +     +G  AKF+ +++  P P V W R    + +  ++ +    +  D
Sbjct: 1760 PSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKPEVEWYRGTTKITDSLRHQITEPYEGDD 1819

Query: 129  V-SLLIKQIGPGDEGEYTCTARNQYGEAIC 157
              SL+I      D   Y C A N+ G+  C
Sbjct: 1820 TYSLIILNTTMEDAAMYKCVAFNEAGKTTC 1849



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 4/102 (3%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMH 1763
            ++   P F   +  + V E   A FE R+   G P   VEW      I   +R  + ++ 
Sbjct: 2347 IVATRPEFKEKLTKVEVTEGDRAKFEVRV--KGYPYPEVEWYHGSNRILDEDRFEIESVK 2404

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            + GY +L +  V  ED+G Y C A+N+ G++   + L V  +
Sbjct: 2405 ETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 39/179 (21%), Positives = 70/179 (39%), Gaps = 9/179 (5%)

Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLR 2541
            E   K+   ++    R E P    E+P   Q L  P +  EG+    E RV   G P   
Sbjct: 2525 EARNKLGFADKSFTIRVEVPKPTGEEPTILQRLQ-PVDTIEGEAIKMECRVS--GKPEPT 2581

Query: 2542 FEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXX 2601
              W  +G+     +R +T  D    TL I  V   D G+Y C A N +G           
Sbjct: 2582 ITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSG------SAHSS 2635

Query: 2602 XXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHV 2660
                ++++  RP   E++Q  ++++ +     +       P+   + +  +   +G ++
Sbjct: 2636 AELTVLEREARPRILEKLQDVDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYI 2694



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 6/130 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  +++  ++  +G    F+C+V   G P  +I W  +G+  A    +    D     
Sbjct: 3140 PEFFRQLR-RVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCK 3196

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L        D G+YTC A+N+ G A++ A +  S  + +V+  +  + +   K+ E +  
Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASLVLS--KPLVM-PEFKERLKNIKVVEGDEA 3253

Query: 3815 RISDAPKEEP 3824
            + S   K EP
Sbjct: 3254 QFSVRVKGEP 3263



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 4/95 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC-DFGFV 3478
            P F   L NI+ + EG+ A F  R+    +P  KVEW+  GK +K+ +RF +   +    
Sbjct: 3236 PEFKERLKNIKVV-EGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             L IS    ED G Y C A N+ G+   +  + V+
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVK 3327



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 5/101 (4%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P FI  + D  ++VEG++   E R+     P   VEW  +G+     +   T  D     
Sbjct: 3431 PLFIAPLHD-QEVVEGETIRLECRVRATPRP--MVEWKKDGRTFKEDYHIYTEFDGQHCT 3487

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLIL 3382
            L I     E+ G YEC+A NK GR  + A L  T KE LI+
Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRGRSVAQL--TVKEALII 3526



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 7/111 (6%)

Query: 3404 MVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL 3463
            M  + D   ++ KG AP     L  +E   EG++A     ++    P   +EW  NG  +
Sbjct: 575  MTFQLDVQPKKPKGTAPEIVSELRPVE-ATEGDDAVLSCTISGKPVPT--IEWLKNGIRV 631

Query: 3464 KAGSRFRTFCDF--GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            K  SR RT CD   G V L I  T  +D G+Y C   N  G A +   +KV
Sbjct: 632  K-DSR-RTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 7/142 (4%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    PEF+   +  I + EG     + R++   +    V+W KDGRP+  S++    
Sbjct: 778  VKEREFAPEFEGDEEGPIVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTKRDIK 835

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
                   L I   ++ D G Y C A N +G+A+ S ++ +  K     + + P  L K++
Sbjct: 836  RRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQVKG---PKGEAPIILSKLR 892

Query: 1022 YLEDASRYSKRTEEEVKITQKP 1043
             +E  +   + T+ +   T KP
Sbjct: 893  PVE--TEEGEETKLKCTFTGKP 912



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 56/230 (24%), Positives = 86/230 (37%), Gaps = 37/230 (16%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            E+   P F  + +  I V EG  V    RV+   +P   +DWF +GRP    ++      
Sbjct: 780  EREFAPEFEGDEEGPIVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTKRDIKRR 837

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809
                 L I      D G Y C A+N+ G A        S   D+ ++ + P+G       
Sbjct: 838  GEEHTLAIHVSSLEDTGVYKCEASNRLGKA--------SRSFDVKVQVKGPKG------- 882

Query: 3810 ELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
                        E PI+      +++++    EE E  + +C    K  P    EW R+G
Sbjct: 883  ------------EAPII------LSKLRPVETEEGEETKLKCTFTGKPAP--TCEWTRDG 922

Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
              + S    +        +L I     +D G Y C   ND G   T A +
Sbjct: 923  IRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEV 972



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 2/77 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG    FE  VE    P L++EWF     +    RY  T D +  ++ I +   ED+G Y
Sbjct: 1202 EGSEAAFEVRVEGF--PKLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGY 1259

Query: 2847 TCKATNSKGSATTSGSL 2863
             C ATN+ G  T+   L
Sbjct: 1260 RCVATNTAGKTTSRADL 1276



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 2/87 (2%)

Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431
            T + P+  + LQ    I EG TA+  C+ +    P   ++W R+   I ++SRI    D 
Sbjct: 1369 TGEEPIIIRKLQ-AQEIDEGSTANLVCK-VTAAKPEPSIKWTRDGVKIRENSRIKMVFDG 1426

Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLG 2458
               S+TI     +DEGVY    +N  G
Sbjct: 1427 ETCSLTIRDATLDDEGVYKVTLTNEYG 1453



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 24/76 (31%), Positives = 39/76 (51%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            LE  V  R  P  ++EWFK   TL   +R+         T++++ L  DDSG+Y C A N
Sbjct: 1586 LELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARN 1645

Query: 2722 LLGEAVSTASIKIEDR 2737
              G +  T ++ ++ +
Sbjct: 1646 KAGSSSRTFNLDVQKK 1661



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 6/101 (5%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITT-FFNF 964
            KPEFK  ++  + + EG  A F+ R++        VEW +    +  S R  IT  +   
Sbjct: 1762 KPEFKQKLRP-LEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITEPYEGD 1818

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
               +L I + T+ DA  Y C A+N  G+ T  A+LT++ K+
Sbjct: 1819 DTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEKQ 1859



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 3/125 (2%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTH--IQNIEGLKDGQSAHFECTVV 3174
            DS TY   A NK G A  SV+L  V   +G KP       +Q ++  +  + + F+    
Sbjct: 2811 DSATYKAVAKNKAGVARRSVEL-LVKPKRGLKPGEAAPEIVQRLKACEVPEGSSFKLRCR 2869

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
                P   IEWY +  P++ + R+          L+   T+  D G Y+  A N  G   
Sbjct: 2870 VTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVS 2929

Query: 3235 TRATI 3239
            T A +
Sbjct: 2930 TSAEL 2934



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 3/84 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT-VYDMGFVS 3888
            P+F  ++K+  V E +  +F  RV+ + +PK  +EW++ GK + S  R+ +   +    +
Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRVKGEPEPK--VEWFKTGKKIKSHARFSSKAGEKHTYT 3293

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L I  V  ED G Y C A ND G+
Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGK 3317



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 5/86 (5%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD--FGY 2433
            P F  P+Q++D I EG  A F   +   G P  KVEW + ++ + +  R++   D     
Sbjct: 3527 PHFDHPIQDLDVI-EGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
              +TI++ +  D G Y C A N  GE
Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGE 3609



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 7/110 (6%)

Query: 58   RQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNK 117
            RQPI    PG   P  F Q  ++    +G  A+   +++G P P + W +    + E  +
Sbjct: 3725 RQPIP---PGAVKPS-FLQRMQDLEIVEGSAARLCVRVQGVPEPEIDWYKDNRVIREGGR 3780

Query: 118  YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS--VYIQPEG 165
                + E+ G   L+I+     D G Y C   N  G+A CS  ++I+  G
Sbjct: 3781 VEFEF-EEDGLCMLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHG 3829



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 4/101 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E + KPE +  ++D +S   G    F+ R+   G    +VEW K    +E   R T  
Sbjct: 388  VQERSTKPEIEDSLRD-VSALPGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIA 444

Query: 962  FNFGYV-ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                 V +L I+ +   DAG Y C A N  G+A + A LT+
Sbjct: 445  EESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI---FRFGY 693
           P+F   LK V A+EG ++  + ++E  G P   IEW +    I  S RF  +      G 
Sbjct: 686 PEFRTKLKPVKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGL 743

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            SL +  L + D+G     A +A+G A ++A L V  R
Sbjct: 744 YSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKER 781



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 42/158 (26%), Positives = 74/158 (46%), Gaps = 12/158 (7%)

Query: 3522 SQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFT-TTPSDLILSENSSAHFECR 3580
            S+L     GTI  +A       T        E    PEF       ++++E +    + R
Sbjct: 749  SKLQLDDTGTIKVVATNASGKATSRADLEVKEREFAPEFEGDEEGPIVVTEGNEVSIQLR 808

Query: 3581 LIPVNDSSMRVEWFHNGKPLLTGSR--VKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
             +  N ++  V+WF +G+P+   ++  +K   +   + + +  +   D G+Y C+A+NR 
Sbjct: 809  -VKANPNA-DVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSL--EDTGVYKCEASNRL 864

Query: 3639 GEATVS--CKLQVKGRQG---IILEPQLPSHFKSGTES 3671
            G+A+ S   K+QVKG +G   IIL    P   + G E+
Sbjct: 865  GKASRSFDVKVQVKGPKGEAPIILSKLRPVETEEGEET 902



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 5/78 (6%)

Query: 2118 LENLK--EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV-ALDILYT 2174
            L+N+K  EGD A F  RV+   +P   ++WF  G+KI++  R+ +     +   L I   
Sbjct: 3242 LKNIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYTLTISDV 3299

Query: 2175 YAEDSGTYMCKATNKLGE 2192
              ED GTY C A+N  G+
Sbjct: 3300 AMEDFGTYKCVASNDAGK 3317



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 38/135 (28%), Positives = 57/135 (42%), Gaps = 8/135 (5%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            IE ++P   P+F+  L   E + EG+    ECRV     P   ++W  +G+  +  +   
Sbjct: 3424 IESKKPA--PLFIAPLHDQE-VVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIY 3478

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEK 2219
            T  D  +  L I     ED G Y C A NK G   +   L V     II    HP  ++ 
Sbjct: 3479 TEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK-EALIIPHFDHP--IQD 3535

Query: 2220 IRQLEAQGHSTRIEV 2234
            +  +E       +EV
Sbjct: 3536 LDVIEGDRAKFHVEV 3550



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 64/231 (27%), Positives = 92/231 (39%), Gaps = 46/231 (19%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHV--FEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA 2289
            ++V+ PK   P F  +L   THV   EG+ +   C+V     P   IE+      + ++ 
Sbjct: 289  VKVKAPKGDAPSFTIDL---THVRAIEGEESKLVCKVTGKPAPT--IEWLKGELPVTTSL 343

Query: 2290 RFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG 2349
            R    F+    +L I+     DAG Y V A N  G   S                     
Sbjct: 344  RVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHS--------------------- 382

Query: 2350 LEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLK 2409
               I EL+  E   +PEI + +   R V   P         G+   F  R+   G P  K
Sbjct: 383  ---IAELQVQERSTKPEIEDSL---RDVSALP---------GERVKFKVRI--GGKPKPK 425

Query: 2410 VEWFRNEKLIEDSSRITKTHDFGYV-SMTISHVRDEDEGVYMCRASNLLGE 2459
            VEW + + +IED  R T   +   V S+ I  + + D G Y C A+N  GE
Sbjct: 426  VEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGE 476



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 4/100 (4%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF--TSIFRFGYI 694
            P F   LK+V+ +EG    FE ++  +  PT  +EW K+   I    RF  T     G  
Sbjct: 1470 PIFQQKLKAVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVY 1527

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
             L +   NI+D+G Y   A +  G   ++A+L V    T+
Sbjct: 1528 VLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNEVLTV 1567



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 2/88 (2%)

Query: 1052 TNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAE 1111
            + ++ EG +   E  V  +      +EWY +G + T+  R+ T  D    ++     +  
Sbjct: 1676 SKEVKEGGTVTLECTVSGKP--APNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGF 1733

Query: 1112 DSGVYTVVARNAAGEAQLSASMTVETRS 1139
            D G Y  VA N  G AQ SA +TV   S
Sbjct: 1734 DDGEYKCVATNPLGSAQSSARLTVTVPS 1761



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 6/106 (5%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V V   P F  +L  P ++ EG  A ++ RI+ YP P   VEWY     +    R++ + 
Sbjct: 1757 VTVPSKPEFKQKLR-PLEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITE 1813

Query: 1898 DF---GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             +      +L IL    ED+  Y C A N  G+      L V  K+
Sbjct: 1814 PYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEKQ 1859



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 6/126 (4%)

Query: 1301 VREDITVMQAPQFSRALHNI-ETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRF 1359
            V E++T+   PQF   +  + E V+G N  L   ++  G     +EW+ N + I    R 
Sbjct: 2150 VEEELTI---PQFIGDVPGVVELVQGDNYDLSLEVR--GTPRPEIEWYHNERLIYATSRV 2204

Query: 1360 RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLE 1419
            + ++      + L +V  +DSG+Y C+A N  G       + V  K+    E    SGL+
Sbjct: 2205 QLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLK 2264

Query: 1420 KIQYLE 1425
             ++  E
Sbjct: 2265 SVEVKE 2270



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 2/77 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG+ I  EC V    +PT  I W  +     +  R K+  D    +L I      D GIY
Sbjct: 2564 EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVCTLTIRDVKLGDEGIY 2621

Query: 2847 TCKATNSKGSATTSGSL 2863
             C A NS GSA +S  L
Sbjct: 2622 RCNAKNSSGSAHSSAEL 2638



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 4/86 (4%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFR-NEKLIEDSSRITKTHDFGY 2433
            RP   + LQ++D+   G+ A F  R+   G P   V+W+R +E++      I +    GY
Sbjct: 2646 RPRILEKLQDVDS-SVGERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGY 2702

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             S+TI ++  EDEG Y     N  GE
Sbjct: 2703 FSLTIEYIDYEDEGAYKAVVINDSGE 2728



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            +P+ L PL+G + + E ++A     +      T   EWY +  ++  + RI++    G  
Sbjct: 8    RPQILQPLEGVD-VKEDENAILSCTISGTP--TPNAEWYRDSIRVRESRRIKSEVVNGMA 64

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             L I   RAED G Y  V RN  G A   A + V
Sbjct: 65   TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 2/87 (2%)

Query: 1054 KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            + +EG+ +    +V  +     T+EW      +T++ R++T  +     L I   R  D+
Sbjct: 309  RAIEGEESKLVCKVTGKP--APTIEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDA 366

Query: 1114 GVYTVVARNAAGEAQLSASMTVETRSS 1140
            G Y VVARN +G A   A + V+ RS+
Sbjct: 367  GTYKVVARNDSGTAHSIAELQVQERST 393



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F    +S T +EG  +    R+   G P  +IEW K+G+++  ++   +  R     L
Sbjct: 492 PRFEKMKESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVL 549

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            +   +  DSG Y C A + +G A+    L V P+
Sbjct: 550 TIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPK 584



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 6/92 (6%)

Query: 2648 LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSIN 2705
            +K    +VEG+ V L A+V  +  P  +IEW K+G T+  T     K   D  ++T+  +
Sbjct: 497  MKESFTVVEGESVELVARVTGKPAP--EIEWTKDGKTVRKTNNVDTKERDDQAVLTIEES 554

Query: 2706 SLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            S   DDSG+Y C A N  G A  T  + ++ +
Sbjct: 555  S--RDDSGLYRCTARNKSGTADMTFQLDVQPK 584



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 6/113 (5%)

Query: 1831 QRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG 1890
            + +  ++V     P F T+L  P K  EG+    + ++E YP P+  +EWY    ++   
Sbjct: 673  ESKTKLKVIAFARPEFRTKLK-PVKAVEGEEVQLDVKVEGYPKPD--IEWYRGTTMIVES 729

Query: 1891 HRYRT---SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             R++      + G  +L I  +  +D+G     A N  G+A S   L V+ +E
Sbjct: 730  GRFKVMEEEEEDGLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKERE 782



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 2/99 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F+ +  GP + +EG       R+   P P +  EW+   + L    R    +      
Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVRGKPQPEL--EWFKYDRTLWKSSRINFKSRDNKFT 1625

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            + +  +  +DSG Y C A N  G +  +  L+VQ K+ I
Sbjct: 1626 MTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 2/81 (2%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            ++EG + +  A  T    P+  V WYKDGR +  S +  +        L + + + EDAG
Sbjct: 1875 VKEGDDLNISA--TIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932

Query: 842  SYTVRAVNKLGEAISTASIRV 862
            SY   A NKLG    T +++V
Sbjct: 1933 SYKCEANNKLGTVTKTYNVKV 1953



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSL 2833
            F   L  +   EGD   FE  V+    P  ++EW+  +  +    R++  S  +  Y SL
Sbjct: 2354 FKEKLTKVEVTEGDRAKFEVRVKGYPYP--EVEWYHGSNRILDEDRFEIESVKETGYYSL 2411

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             +    +ED+G+Y C A N  G +T    L
Sbjct: 2412 TVGEVVQEDAGMYKCIAVNKAGKSTCRADL 2441



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP     +K   V E  +  F+ R    G P   +EW ++ +P++ + R+   H      
Sbjct: 2846 APEIVQRLKACEVPEGSS--FKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            LN       D G Y   A N LG   TS+ L ++   S
Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVS 2941



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 8/83 (9%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV---HTLNDFGFIALDIDYIYA 3762
            +VPEG      CRV   G PT  I+W+ +  P     RV   HT + +    L+ +   A
Sbjct: 2857 EVPEGSSFKLRCRV--TGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETE---A 2911

Query: 3763 RDAGEYTCRATNKWGSATTTAKI 3785
            RD G Y   A N  GS +T+A++
Sbjct: 2912 RDEGRYMLVAKNHLGSVSTSAEL 2934



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 6/122 (4%)

Query: 1438 ESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH 1497
            +S  I P F  + + +E  ++G    FECK+    +   ++ W K+G+ + I    +P +
Sbjct: 3134 KSKGIIPEFFRQLRRVE-AVQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYIKPFY 3190

Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            D     L   +   ED G YTC A N  G  E S   +   +  +V     E  L+ I+V
Sbjct: 3191 DGEVCKLTFYETQPEDEGDYTCVASNEAG--EASSHASLVLSKPLVMPEFKER-LKNIKV 3247

Query: 1558 LE 1559
            +E
Sbjct: 3248 VE 3249



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 7/139 (5%)

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
            S  K   ++ ES    P F+  P   + V+EG+ +  EC++         VEW K+G+  
Sbjct: 3415 SASKSFTVVIESKKPAPLFIA-PLHDQEVVEGETIRLECRVRATPRP--MVEWKKDGRTF 3471

Query: 1488 TIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
               +      D  +  L I     ED G Y C A N  G      +LT +    I     
Sbjct: 3472 KEDYHIYTEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKEALII---PH 3528

Query: 1548 NEAGLEQIQVLE-DRSKYH 1565
             +  ++ + V+E DR+K+H
Sbjct: 3529 FDHPIQDLDVIEGDRAKFH 3547



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP+F  P+ D  V E +    E R+     P+  VEW ++G   +    + T  D  +  
Sbjct: 3430 APLFIAPLHDQEVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYTEFDGQHCT 3487

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            L +K    ED G Y C A N+ G   + + L V+
Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK 3521



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 2/96 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P+F +   +   VEG +V L  R+   G     +EW  +GK ++  +        D   L
Sbjct: 492  PRFEKMKESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVL 549

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
             +     +DSG+Y C A N+ G A  +  L V  KK
Sbjct: 550  TIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKK 585



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 10/110 (9%)

Query: 1302 REDITVMQ---APQFSRALHN-IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI--KT 1355
            R D+ V +   AP+F       I   EG  V ++ R++   +    V+WF +G+PI   T
Sbjct: 773  RADLEVKEREFAPEFEGDEEGPIVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYEST 830

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                +   E   +A+ + S+  ED+GVY C+A+N+LG+A  S  ++V  K
Sbjct: 831  KRDIKRRGEEHTLAIHVSSL--EDTGVYKCEASNRLGKASRSFDVKVQVK 878



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 2/102 (1%)

Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
            V++   +  AP     L + E  EG  V LEC +   G     +EW+ +G       R  
Sbjct: 1658 VQKKKVIGNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVM 1715

Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
              ++    ++        D G Y C ATN LG A +S  L V
Sbjct: 1716 TTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 6/102 (5%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT-- 1094
            V +  KP F   L+   ++VEG  A F+ R++  S     VEWY    +IT + R Q   
Sbjct: 1757 VTVPSKPEFKQKLRPL-EVVEGSEAKFDVRIK--SYPKPEVEWYRGTTKITDSLRHQITE 1813

Query: 1095 -YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             Y      +L I +   ED+ +Y  VA N AG+    A +TV
Sbjct: 1814 PYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTV 1855



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 2/81 (2%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            V EG  +++ AT+     P+  V WY +GR V    + +T        L +  A  ED G
Sbjct: 1875 VKEGDDLNISATIA--GKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932

Query: 2049 TYMCKATNAVGEAVTTSSVKV 2069
            +Y C+A N +G    T +VKV
Sbjct: 1933 SYKCEANNKLGTVTKTYNVKV 1953



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 2/89 (2%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            + E   P F   + G  EL +G +  Y+  +   G P    EWY N   +   SR + + 
Sbjct: 2151 EEELTIPQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSF 2208

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                 T+ + +V  +D+GLY CKA+N AG
Sbjct: 2209 ISSKATIALYNVTLDDSGLYRCKAVNTAG 2237



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 40/160 (25%), Positives = 72/160 (45%), Gaps = 18/160 (11%)

Query: 2206 NIILDTQHPNGLEKIRQLEAQGHSTR-----IEVEEPKISPPRFVTELRGTTHVFEGKTA 2260
            N+ LD    +GL + + +   G  ++     ++ + P+ + P  V+ L+ +  V EG+ A
Sbjct: 2219 NVTLDD---SGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLK-SVEVKEGEQA 2274

Query: 2261 HFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAI 2320
              E  V     P L  E+Y +G  ++ + R   T + G   L I     ED G Y  +  
Sbjct: 2275 ELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDMGTYKCQVR 2332

Query: 2321 NALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360
            N LG  +++  + +         + RPE  EK+ ++E  E
Sbjct: 2333 NDLGRTSTSAHLNIIV-------ATRPEFKEKLTKVEVTE 2365



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P  +  LKSV   EG +   E  +   G PT  +EW ++G  ++ S R  S    G   L
Sbjct: 2257 PNIVSGLKSVEVKEGEQAELEFVVS--GTPTPTLEWYRDGLRVKESRRVRSTLENGIARL 2314

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +     +D G Y C+  +  G   T A L++
Sbjct: 2315 VITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 5/99 (5%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR--TFCDFGF 3477
            P F   L+ +E + EG+ A FE R+     P  +VEWY     +    RF   +  + G+
Sbjct: 2352 PEFKEKLTKVE-VTEGDRAKFEVRVKGYPYP--EVEWYHGSNRILDEDRFEIESVKETGY 2408

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
              L +     ED+G Y C A N  G++   A ++V  ++
Sbjct: 2409 YSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQ 2447



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 32/100 (32%), Positives = 47/100 (47%), Gaps = 4/100 (4%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            ++ P  VQ L     V EG +  L CR+   G PT  +EW+ +   +    R    +   
Sbjct: 2844 EAAPEIVQRLK-ACEVPEGSSFKLRCRVT--GTPTPTIEWYKSNMPLKPNGRVIIGHTGD 2900

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273
               L+ +   + D G Y + A NHLGS  TSA + +IE S
Sbjct: 2901 QYFLNFLETEARDEGRYMLVAKNHLGSVSTSAEL-IIEPS 2939



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 3/91 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+  +  V+G     E +V    +P  +I W K+G  L     +K  +D  +  
Sbjct: 3140 PEFFRQLRRVEA-VQGSTARFECKVSGHPEP--QIAWLKDGKELAIPRYIKPFYDGEVCK 3196

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
            L+    + +D G YTC A+N  GEA S AS+
Sbjct: 3197 LTFYETQPEDEGDYTCVASNEAGEASSHASL 3227



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 4/94 (4%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF-RPIHDFG 1500
            + P F  R K+I+ V+EG    F  +++   +   KVEWFK G+ +    RF     +  
Sbjct: 3234 VMPEFKERLKNIK-VVEGDEAQFSVRVKGEPEP--KVEWFKTGKKIKSHARFSSKAGEKH 3290

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
               L I D+  ED G Y C A N  G  + S RL
Sbjct: 3291 TYTLTISDVAMEDFGTYKCVASNDAGKVQCSGRL 3324



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 11/116 (9%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT-LNDFGFI 3753
            P F   +K NI V EG    F  RV+  G+P  +++WF  G+   + +R  +   +    
Sbjct: 3236 PEFKERLK-NIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809
             L I  +   D G Y C A+N  G      K+ CS + D V E  +P  +S + ++
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAG------KVQCSGRLD-VKERMVPPEISTDVLE 3341



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P    P++ + V E++ A     +   G P    EW R+ + +  S R+ +    G   L
Sbjct: 9    PQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATL 66

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
             +K    ED G Y C   NE G A + + L V+
Sbjct: 67   TIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 39/158 (24%), Positives = 68/158 (43%), Gaps = 6/158 (3%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQ---APRFITQLNGPTKLSEGQSAH 1863
            SL ++   E+   + + +  +   +     ++ VN+    PRF  ++     + EG+S  
Sbjct: 452  SLIIQDLEETDAGRYKCVATNEAGEAESMAQLTVNEELIGPRF-EKMKESFTVVEGESVE 510

Query: 1864 YECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923
               R+   P P   +EW  +GK ++  +   T      A L I     +DSG Y C A N
Sbjct: 511  LVARVTGKPAPE--IEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLYRCTARN 568

Query: 1924 NLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
              G A  + +L+VQ K+      +  S L  ++  E D
Sbjct: 569  KSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGD 606



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P+ +  L+ + E  EG +A     ++    PT  +EW K+G  +  S R       G V 
Sbjct: 591 PEIVSELRPV-EATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEVK 647

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
           L I   RA+D G YT    N+LG A S   ++V A
Sbjct: 648 LTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIA 682



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 5/100 (5%)

Query: 1038 KITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTY 1095
            ++  +P F   LK  + I EG+S  FE ++        TVEW+ +  QI    R  I   
Sbjct: 1465 EVGSRPIFQQKLKAVSTI-EGESTRFEVKLSAMP--RPTVEWFKSSSQIYDGGRFTITEE 1521

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             + G   L I     ED+G Y VVA N  G+    A + V
Sbjct: 1522 ENSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV 1561



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 38/154 (24%), Positives = 63/154 (40%), Gaps = 10/154 (6%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            +VI  AP     +    V E      E  +   G P   +EW ++G+   A+ R+ T  D
Sbjct: 1662 KVIGNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFD 1719

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824
                ++        D G Y C A N LG A +S+ L V   +  + +       QK++ L
Sbjct: 1720 GSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSKPEFK-------QKLRPL 1772

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSE 1858
            E     + + DV +     P  +    G TK+++
Sbjct: 1773 EVVEGSEAKFDVRIKSYPKPE-VEWYRGTTKITD 1805



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/123 (25%), Positives = 64/123 (52%), Gaps = 8/123 (6%)

Query: 2776 FISHLNNIV-CKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            FI  +  +V   +GDN  ++ ++E    P  +IEW+ N + + + +R + +   S  ++ 
Sbjct: 2159 FIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIA 2216

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVE--QAEE 2892
            + +   +DSG+Y CKA N+ G+ +   ++     +    +   P   +GL++VE  + E+
Sbjct: 2217 LYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRP---EGTEPNIVSGLKSVEVKEGEQ 2273

Query: 2893 ARL 2895
            A L
Sbjct: 2274 AEL 2276



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFT--PIYDFGY 4030
            P F  ++ ++  + E +  KFE ++   G P  +VEW+     +L ++RF    + + GY
Sbjct: 2352 PEFKEKL-TKVEVTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESVKETGY 2408

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
             ++  G V  ED+G Y C A N  G    +A
Sbjct: 2409 YSLTVGEVVQEDAGMYKCIAVNKAGKSTCRA 2439



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 61/263 (23%), Positives = 105/263 (39%), Gaps = 41/263 (15%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            +++ E +   P     L  VE+ EG    F+ RL         VEWY   + + +   F 
Sbjct: 2933 ELIIEPSVSPPSFRHRLTAVEVDEGDETRFDVRL---KKEPTSVEWYKEQQRIFTDGHFE 2989

Query: 1628 --ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
              E       +L I +    D+G Y C A+N  G++ T    +V           +E  +
Sbjct: 2990 VIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLV-----------NERLI 3038

Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
            P   +  D   Y+     D +   A V   P  +IR  +++    E++ +      L V 
Sbjct: 3039 PPGFEGPDHGSYELQEG-DTITLDAVVKGNPYPEIRWYKDEFLAMESKKL-----MLSVR 3092

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                    +  N LT  H           V P+DSG Y C   N++G A  S T+ V++K
Sbjct: 3093 --------DRKNSLTLYH-----------VIPKDSGVYKCVLKNKVGTATKSFTVDVEAK 3133

Query: 1806 ASLQLESQHESALQKIQQLEDSS 1828
             S  +  +    L++++ ++ S+
Sbjct: 3134 KSKGIIPEFFRQLRRVEAVQGST 3156



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 34/101 (33%), Positives = 44/101 (43%), Gaps = 3/101 (2%)

Query: 1171 EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY 1230
            E  K  P+F+ PL +   V EG+ I LECR+     P   VEW  +GR+        T +
Sbjct: 3425 ESKKPAPLFIAPLHDQEVV-EGETIRLECRVR--ATPRPMVEWKKDGRTFKEDYHIYTEF 3481

Query: 1231 DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            D     L I  A   D G Y   A N  G   + A + V E
Sbjct: 3482 DGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVKE 3522



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD--FSYVSLDITHTYEEDSG 2844
            EGD   F  +VE S  P  K+EW   ++ L +G R     D       L IT+    DSG
Sbjct: 3540 EGDRAKF--HVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSG 3597

Query: 2845 IYTCKATNSKGSATTSGSL 2863
             YTC A N  G  T  G L
Sbjct: 3598 KYTCIARNKAGENTCHGRL 3616



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 3/94 (3%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            +P+   P++  + +KE   A     +   G  T   EW +D   V  S RI +    G  
Sbjct: 8    RPQILQPLEG-VDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             LTIK     D G Y C   N  G AT+ A L +
Sbjct: 65   TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+ +  ++   V+E E     C +     P    EWYR+   +    R ++    G  +L
Sbjct: 9    PQILQPLEGVDVKEDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSEVVNGMATL 66

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
             I    AED GEY C   N+ G   +KA ++ +
Sbjct: 67   TIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            E ++  L   +     PN   EW+++ + +    R+KS    G+ TL+I   R +D G Y
Sbjct: 22   EDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSEVVNGMATLTIKQTRAEDQGEY 79

Query: 2716 TCKATNLLGEAVSTASIKI 2734
             C   N  G A S A + +
Sbjct: 80   KCVLRNEHGTATSKAPLNV 98



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 61/216 (28%), Positives = 81/216 (37%), Gaps = 40/216 (18%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493
            EGE+    AR+T    P  ++EW  +GK+++  +   T       +L I  +  +DSG Y
Sbjct: 505  EGESVELVARVTGKPAP--EIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLY 562

Query: 3494 LCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAE 3553
             C A N  G A  T  + VQ K+        PKG                      PE  
Sbjct: 563  RCTARNKSGTADMTFQLDVQPKK--------PKG--------------------TAPEIV 594

Query: 3554 SGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG 3613
            S   P   T   D +LS   S     + +P       +EW  NG  +    R K     G
Sbjct: 595  SELRPVEATEGDDAVLSCTISG----KPVPT------IEWLKNGIRVKDSRRTKCDLVDG 644

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             V L I      D G YTC   N  G A    KL+V
Sbjct: 645  EVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 47/199 (23%), Positives = 76/199 (38%), Gaps = 28/199 (14%)

Query: 804  VEWYKDGRPITASSR-ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            V+W+KD   +    R I    + G  SL I  +R ED G+Y     N+ G+  + A + +
Sbjct: 1012 VDWFKDEVMLNDEGRFIMEGGDNGRFSLTISDVRPEDKGTYKCLVFNESGKVTTRAKLCI 1071

Query: 863  AARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIK 922
              +  + A    PE+    E                   VP     P+   P+ + + + 
Sbjct: 1072 --KEAIVA----PEEVDAAE------------------TVPIEGSAPKITKPL-ESVEVN 1106

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHY 982
            EG    F+      G  +  VEW KD   +  S R+    +     L  K     D G Y
Sbjct: 1107 EG--EDFDLECVVSGSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVFKQARPEDIGEY 1164

Query: 983  TCRAYNAIGQATTSANLTI 1001
             C   N  G+A+T+  + +
Sbjct: 1165 KCTVINEHGKASTTGEVKV 1183



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 5/132 (3%)

Query: 1408 LILESQHPS--GLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFE 1465
            L+ +   P   G  K   + +  +   T  +  +V  +P F  +   +E V EG    FE
Sbjct: 1151 LVFKQARPEDIGEYKCTVINEHGKASTTGEVKVNVLSRPEFKIKMSPVE-VTEGSEAAFE 1209

Query: 1466 CKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525
             ++E      L+VEWFK    +    R+    D     + I ++  ED+G Y C A N  
Sbjct: 1210 VRVEGFP--KLQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTA 1267

Query: 1526 GTDEVSCRLTCR 1537
            G       LT +
Sbjct: 1268 GKTTSRADLTVK 1279



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV-A 2036
            P+F + +KN +V EG        +    +P  +VEW+  G+ ++   RF +     +   
Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L I     ED GTY C A+N  G+   +  + V
Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGKVQCSGRLDV 3326



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 9/113 (7%)

Query: 1305 ITVMQA---PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR--F 1359
            +TV +A   P F   + +++ +EG        +   G    +VEW    + ++ G R   
Sbjct: 3518 LTVKEALIIPHFDHPIQDLDVIEGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSL 3575

Query: 1360 RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILES 1412
                E     L + +  P DSG YTC A N+ GE   +C  R+  K+ ++  S
Sbjct: 3576 EEDRETQMYFLTITNCKPTDSGKYTCIARNKAGE--NTCHGRLAVKEKMVTPS 3626



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 60/249 (24%), Positives = 95/249 (38%), Gaps = 46/249 (18%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYV 2035
            KP F   +K  +  EG  V  +  +     P   V WY     +    RF+       +V
Sbjct: 103  KPSFTSKMKPVDAEEGQEVRFDVHVK--GSPKPDVVWYKGSTMIGTHERFQIVEAAEDHV 160

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L I     ED  TY   ATN VG+  + + ++V                      E+  
Sbjct: 161  TLVISEVKLEDAETYKVVATNDVGKVTSRADLRVK---------------------ERQF 199

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
             P+ I+EE+    P+  T          GD     C V     P  +I W+ NG+ +   
Sbjct: 200  APEFIDEERG---PIDATT---------GDEVTLTCSVS--GKPKPSITWYKNGKLLTDS 245

Query: 2156 HRY--RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR----NIIL 2209
             +   R++ +  +V +  L    ED+  Y C+A NKLG+A     +KV   +    +  +
Sbjct: 246  LKLDIRSSGERNWVTM--LSAKPEDTALYKCEAENKLGKASRAFDVKVKAPKGDAPSFTI 303

Query: 2210 DTQHPNGLE 2218
            D  H   +E
Sbjct: 304  DLTHVRAIE 312



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F + L  V A+EG +     ++   G P   IEWLK    +  S R  + F     +L
Sbjct: 299 PSFTIDLTHVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDFEKNVATL 356

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
            +    + D+G Y   A + +G A + A L V  R+T
Sbjct: 357 VIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERST 393



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 3/91 (3%)

Query: 65  RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
           +P   +P I  ++ +     +G +A     + G P P + W +    + +  +   + + 
Sbjct: 585 KPKGTAPEIVSEL-RPVEATEGDDAVLSCTISGKPVPTIEWLKNGIRVKDSRR--TKCDL 641

Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
             G+V L IK     D+G+YTC  RN+ G A
Sbjct: 642 VDGEVKLTIKTTRADDQGDYTCIVRNELGSA 672



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 58/241 (24%), Positives = 103/241 (42%), Gaps = 43/241 (17%)

Query: 1032 RTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSA 1089
            +T+ +V    +P F   LK   K VEG+    + +VE  P+ D    +EWY     I  +
Sbjct: 675  KTKLKVIAFARPEFRTKLKPV-KAVEGEEVQLDVKVEGYPKPD----IEWYRGTTMIVES 729

Query: 1090 NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRG 1149
             R +   +             E+ G+Y++V      + QL  + T++    + T++  + 
Sbjct: 730  GRFKVMEE------------EEEDGLYSLVI----SKLQLDDTGTIKV---VATNASGKA 770

Query: 1150 LYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTM 1209
                   ++E +F  P ++ +E              P  V+EG  + ++ R++   +P  
Sbjct: 771  TSRADLEVKEREFA-PEFEGDE------------EGPIVVTEGNEVSIQLRVK--ANPNA 815

Query: 1210 RVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS-ADTGEYTVRAVNHLGSAHTSAIVR 1268
             V+WF +GR +   ++ +     G      IH +S  DTG Y   A N LG A  S  V+
Sbjct: 816  DVDWFKDGRPIYESTK-RDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVK 874

Query: 1269 V 1269
            V
Sbjct: 875  V 875



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 38/148 (25%), Positives = 68/148 (45%), Gaps = 9/148 (6%)

Query: 2216 GLEKIRQLEAQGHSTR---IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDP 2272
            G  K+    A G +T    +EV+E + +P  F  +  G   V EG     + +V+   +P
Sbjct: 757  GTIKVVATNASGKATSRADLEVKEREFAP-EFEGDEEGPIVVTEGNEVSIQLRVKA--NP 813

Query: 2273 NLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISM 2332
            N  ++++ +G+ +  + +  I       +L I     ED G Y  +A N LG  + +  +
Sbjct: 814  NADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDV 873

Query: 2333 TVTAKGSIISESQRPEGLEKIRELESAE 2360
             V  KG    + + P  L K+R +E+ E
Sbjct: 874  KVQVKG---PKGEAPIILSKLRPVETEE 898



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 2/115 (1%)

Query: 1549 EAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDAT 1608
            + G  +  V+ +  K   T  V       P     +  VE+ EG  A FE R+       
Sbjct: 1160 DIGEYKCTVINEHGKASTTGEVKVNVLSRPEFKIKMSPVEVTEGSEAAFEVRV--EGFPK 1217

Query: 1609 LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT 1663
            L+VEW+     ++   R+T T +     + I +   ED+G Y C A N  G+  +
Sbjct: 1218 LQVEWFKGMTKIEDSGRYTFTADKNRYTMVIANVTLEDAGGYRCVATNTAGKTTS 1272



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 4093 SWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTG-HPKPRVMWLLNGNTI 4151
            SW+V  +Q   ++     P+ +    A  ++EG  A   C+VT   P+P + W  +G  I
Sbjct: 1356 SWEVKVKQSAPKTTGE-EPIIIRKLQAQEIDEGSTANLVCKVTAAKPEPSIKWTRDGVKI 1414

Query: 4152 VNGSRYKLTYDG 4163
               SR K+ +DG
Sbjct: 1415 RENSRIKMVFDG 1426



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 4/117 (3%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E+P   + ++  E+ EG   +L   +T    P   ++W  +G  +++  R K  +D    
Sbjct: 1371 EEPIIIRKLQAQEIDEGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIKMVFDGETC 1429

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092
            +L I  A  +D G Y    TN  G A +T  V V+         + +Q+LK +  +E
Sbjct: 1430 SLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGS---RPIFQQKLKAVSTIE 1483



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 2/114 (1%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P+ ++ L     + EG   +L C++     P   ++W  +G  +   SR K  +D    
Sbjct: 1372 EPIIIRKLQ-AQEIDEGSTANLVCKVTA-AKPEPSIKWTRDGVKIRENSRIKMVFDGETC 1429

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQ 1289
            +L I  AT  D G Y V   N  G+A ++  V V E        Q  +A+  I+
Sbjct: 1430 SLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVGSRPIFQQKLKAVSTIE 1483



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 35/119 (29%), Positives = 63/119 (52%), Gaps = 8/119 (6%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD--FGI 3339
            P F  +++ V+  +EG+S  FE +L  +  P   VEWF +  ++  G R+    +   G+
Sbjct: 1470 PIFQQKLKAVST-IEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGV 1526

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398
             +L I     E++G Y+ VA N LG+ +++A L+    E L +   + +  EG +EK +
Sbjct: 1527 YVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV--NEVLTVPEFMDKA-EGPIEKTE 1582



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 35/106 (33%), Positives = 51/106 (48%), Gaps = 6/106 (5%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            PE  Q P F + +  Q+ + EGG       +      T  V+W +DG PV    RI+   
Sbjct: 1958 PEG-QAPSFTSEMS-QVEVDEGGEVKLYFLISGYPKPT--VKWTRDGIPVFEDYRISMDS 2013

Query: 963  N-FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
            +    V L I++VT +D G Y C   N  G  TT+  + IVT++ I
Sbjct: 2014 SRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQV-IVTQRSI 2058



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 3/99 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYIS 695
            P F   +K+V    G  + FE ++E  G P   + + +  + I    R++ +    G   
Sbjct: 2060 PIFGQKMKNVEGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFV 2117

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            L + +   +D+GEY C AV+  G   +K  LHV    TI
Sbjct: 2118 LTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI 2156



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/118 (23%), Positives = 50/118 (42%), Gaps = 2/118 (1%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  +  +  L +GD  +++  +E    P   I+W+HN + I A  R + +       
Sbjct: 2157 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226
            + +     +DSG Y CKA N  G       + V   R    +    +GL+ +   E +
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVEVKEGE 2272



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG+   LE  +   G PT  +EW+ +G  V    R ++  + G   L I    + D G
Sbjct: 2268 VKEGEQAELEFVVS--GTPTPTLEWYRDGLRVKESRRVRSTLENGIARLVITETWAEDMG 2325

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLE-DAARRTKQVR 1302
             Y  +  N LG   TSA + +I    + T  + ++ + ++++ E D A+   +V+
Sbjct: 2326 TYKCQVRNDLGRTSTSAHLNII----VATRPEFKEKLTKVEVTEGDRAKFEVRVK 2376



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 4/117 (3%)

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQ--LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFN 1883
            D+ + Q    ++V     P  I+   L GP  L+EG        +   P P++  +WY +
Sbjct: 3314 DAGKVQCSGRLDVKERMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDL--QWYKD 3371

Query: 1884 GKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            G +++       S+     +L I+ V  ED+G   C A+N  G A  S  + ++SK+
Sbjct: 3372 GVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKK 3428



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P+F  PL +   + EG+T   +CR+     P   VEW ++ +  ++   I    D  + +
Sbjct: 3431 PLFIAPLHD-QEVVEGETIRLECRVRATPRPM--VEWKKDGRTFKEDYHIYTEFDGQHCT 3487

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I   + EDEG Y C A N  G
Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEG 3510



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 4/89 (4%)

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN---HTTLRVRNTQ 329
            ++  +++G  A+F  ++ G P P VTW +  +++  ++   +   H    H+ L      
Sbjct: 5135 KDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALHEGEVHSLLITEGGY 5194

Query: 330  KSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            K DSG Y  +A+N  G   T G+L VE P
Sbjct: 5195 K-DSGVYKCIAKNSAGQDTTVGHLFVEGP 5222



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           PQ + PL+ V   E         I   G PT   EW ++   +  S R  S    G  +L
Sbjct: 9   PQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATL 66

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            +     +D GEY C   +  G A +KA L+V
Sbjct: 67  TIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 10/111 (9%)

Query: 1302 REDITVMQ---APQF-SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            R D+ V +   AP+F       I+   G  V L C +   G     + W+ NGK +    
Sbjct: 189  RADLRVKERQFAPEFIDEERGPIDATTGDEVTLTCSVS--GKPKPSITWYKNGKLLTDSL 246

Query: 1358 RF--RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
            +   R + E ++V +  LS  PED+ +Y C+A N+LG+A  +  ++V A K
Sbjct: 247  KLDIRSSGERNWVTM--LSAKPEDTALYKCEAENKLGKASRAFDVKVKAPK 295



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 35/127 (27%), Positives = 50/127 (39%), Gaps = 3/127 (2%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +S L  +   EGD+    C +     PT  IEW  N   +    R K       V L I 
Sbjct: 594  VSELRPVEATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEVKLTIK 651

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLA 2896
             T  +D G YTC   N  GSA +   L+        F T+    KA +E  E   + ++ 
Sbjct: 652  TTRADDQGDYTCIVRNELGSAESKTKLKVIAFARPEFRTKLKPVKA-VEGEEVQLDVKVE 710

Query: 2897 KGRRPSV 2903
               +P +
Sbjct: 711  GYPKPDI 717



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 10/160 (6%)

Query: 2196 TCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVF 2255
            TC+L +   R+  LD +    +    +      + R+ V E   S P F  +L+  + + 
Sbjct: 1428 TCSLTI---RDATLDDEGVYKVTLTNEYGTASSTCRVLVNEVG-SRPIFQQKLKAVSTI- 1482

Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD--FGYVSLDIQHCVPEDAG 2313
            EG++  FE ++  +  P   +E++ +   +    RF IT +   G   L I+    EDAG
Sbjct: 1483 EGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDAG 1540

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEG-LEK 2352
             Y V A N LG  TS   + V    ++     + EG +EK
Sbjct: 1541 TYKVVAYNNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEK 1580



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 5/101 (4%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD- 2696
            V   PIF   LK+    +EG+    E ++     P   +EWFK+   +  G R   T + 
Sbjct: 1466 VGSRPIFQQKLKAVST-IEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEE 1522

Query: 2697 -FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
              G+  L I     +D+G Y   A N LG+  S A +++ +
Sbjct: 1523 NSGVYVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLRVNE 1563



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD---GMYHF 4167
            P+F     AV+  EGE  RF  +++  P+P V W  + + I +G R+ +T +   G+Y  
Sbjct: 1470 PIFQQKLKAVSTIEGESTRFEVKLSAMPRPTVEWFKSSSQIYDGGRFTITEEENSGVYVL 1529

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199
             I  T   D G  +V+             L+V
Sbjct: 1530 VIEDTNIEDAGTYKVVAYNNLGKVTSQALLRV 1561



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 4/129 (3%)

Query: 1812 SQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL--SEGQSAHYECRIE 1869
            +  ++A+ K     ++ +   R D+ V   Q P      +G   +   EG   +    I 
Sbjct: 1829 TMEDAAMYKCVAFNEAGKTTCRADLTVIEKQQPPTFLGDDGTQTIIVKEGDDLNISATIA 1888

Query: 1870 PYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929
              P P   V WY +G+++    +  T      + L +     ED+G Y C+A N LG   
Sbjct: 1889 GKPSPE--VSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVT 1946

Query: 1930 SSIRLNVQS 1938
             +  + V S
Sbjct: 1947 KTYNVKVMS 1955



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 26/124 (20%), Positives = 57/124 (45%), Gaps = 3/124 (2%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ++E +TI P+F+     +  +++G +  ++  LE       ++EW+ N + +    R + 
Sbjct: 2150 VEEELTI-PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQL 2206

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555
                    + + ++  +DSG+Y C+AVN  GT      +  +            +GL+ +
Sbjct: 2207 SFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSV 2266

Query: 1556 QVLE 1559
            +V E
Sbjct: 2267 EVKE 2270



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 2/116 (1%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            EE+   P F   +  +  L +G+N  ++  L     P  ++EWY N + + A SR +   
Sbjct: 2151 EEELTIPQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSF 2208

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGME 3529
                  + +     +DSG Y C+A N  G      ++ VQ KR    E  +  G++
Sbjct: 2209 ISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLK 2264



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 2/116 (1%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+  +     + +G N  L   LE  G P   +EW+HN R +   SR +  +      
Sbjct: 2157 PQFIGDVPGVVELVQGDNYDLS--LEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLE 1292
            + + + T  D+G Y  +AVN  G+      + V  +    T+      ++ +++ E
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVEVKE 2270



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 38/125 (30%), Positives = 59/125 (47%), Gaps = 12/125 (9%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            +P  V+  KS+E V EG+    E  +       L  EW+++G  V    R R   + G  
Sbjct: 2256 EPNIVSGLKSVE-VKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIA 2312

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE--AGLEQIQVLE- 1559
             L I +  AED G Y C+  N +G    S  L      +I+ +T+ E    L +++V E 
Sbjct: 2313 RLVITETWAEDMGTYKCQVRNDLGRTSTSAHL------NIIVATRPEFKEKLTKVEVTEG 2366

Query: 1560 DRSKY 1564
            DR+K+
Sbjct: 2367 DRAKF 2371



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 6/99 (6%)

Query: 3823 EPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            EP VS PP F  ++ +  V+E +  RF+ R+  K++P   +EWY+  + + +   +  + 
Sbjct: 2937 EPSVS-PPSFRHRLTAVEVDEGDETRFDVRL--KKEPT-SVEWYKEQQRIFTDGHFEVIE 2992

Query: 3883 --DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
              +    SL I      D+G Y C A+N+ G+  T+A +
Sbjct: 2993 GEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL 3031



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--RFGY 693
            PP F   L +V   EG +  F+ R++   +PT  +EW K  Q I     F  I       
Sbjct: 2942 PPSFRHRLTAVEVDEGDETRFDVRLKK--EPT-SVEWYKEQQRIFTDGHFEVIEGEEECL 2998

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
             SL + +  + D+G Y C A++ +G + T+A L V  R
Sbjct: 2999 YSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 5/105 (4%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E+   P F  PI+D + + EG  A F   +E  G    +VEWLK  + +    R++  
Sbjct: 3520 VKEALIIPHFDHPIQD-LDVIEGDRAKFH--VEVSGKPAAKVEWLKGDQELRNGGRVSLE 3576

Query: 962  FN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
             +       LTI +    D+G YTC A N  G+ T    L +  K
Sbjct: 3577 EDRETQMYFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAVKEK 3621



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 7/116 (6%)

Query: 2625 AMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684
            A +K P   ++  V   P FT+ +K  D   EGQ V  +  V+    P+  + W+K    
Sbjct: 90   ATSKAP---LNVRVPVKPSFTSKMKPVDA-EEGQEVRFDVHVKGSPKPD--VVWYKGSTM 143

Query: 2685 LTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHW 2739
            + T  R +        VTL I+ ++ +D+  Y   ATN +G+  S A +++++R +
Sbjct: 144  IGTHERFQIVEAAEDHVTLVISEVKLEDAETYKVVATNDVGKVTSRADLRVKERQF 199



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 8/105 (7%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSANRIQT 1094
            V++  KP F   +K  +   EGQ   F+  V+  P+ D    V WY     I +  R Q 
Sbjct: 98   VRVPVKPSFTSKMKPVDA-EEGQEVRFDVHVKGSPKPD----VVWYKGSTMIGTHERFQI 152

Query: 1095 YHDF-GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
                  +V L I+ V+ ED+  Y VVA N  G+    A + V+ R
Sbjct: 153  VEAAEDHVTLVISEVKLEDAETYKVVATNDVGKVTSRADLRVKER 197



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 6/99 (6%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL--KSTFD 2696
            Q AP F    +       G  V L   V  +  P+  I W+KNG  LT   +L  +S+ +
Sbjct: 198  QFAPEFIDEERGPIDATTGDEVTLTCSVSGKPKPS--ITWYKNGKLLTDSLKLDIRSSGE 255

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
               VT+   S + +D+ +Y C+A N LG+A     +K++
Sbjct: 256  RNWVTML--SAKPEDTALYKCEAENKLGKASRAFDVKVK 292



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 62/247 (25%), Positives = 92/247 (37%), Gaps = 42/247 (17%)

Query: 2090 ELEKYERPKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHN 2148
            +L K  R   ++ + P G  P F   LT +  + EG+ +   C+V     P  TI+W   
Sbjct: 279  KLGKASRAFDVKVKAPKGDAPSFTIDLTHVRAI-EGEESKLVCKVT--GKPAPTIEWLKG 335

Query: 2149 GQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNII 2208
               +    R RT  +     L I  T   D+GTY   A N  G A               
Sbjct: 336  ELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTA--------------- 380

Query: 2209 LDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEP 2268
                       I +L+ Q  ST+ E+E+           LR  +    G+   F+ ++  
Sbjct: 381  ---------HSIAELQVQERSTKPEIED----------SLRDVS-ALPGERVKFKVRIG- 419

Query: 2269 VHDPNLRIEFYHNGKALQSAARFHITFDFGYV-SLDIQHCVPEDAGEYSVKAINALGHCT 2327
               P  ++E+      ++   RF I  +   V SL IQ     DAG Y   A N  G   
Sbjct: 420  -GKPKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEAE 478

Query: 2328 SAISMTV 2334
            S   +TV
Sbjct: 479  SMAQLTV 485



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 2/74 (2%)

Query: 793 QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRA-EDAGSYTVRAVNKL 851
           QL   ++P   V+W+KDGRPI  S++   I   G      +H+ + ED G Y   A N+L
Sbjct: 806 QLRVKANPNADVDWFKDGRPIYESTK-RDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRL 864

Query: 852 GEAISTASIRVAAR 865
           G+A  +  ++V  +
Sbjct: 865 GKASRSFDVKVQVK 878



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 2/106 (1%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    PEF    +  I   EG       R+   G     +EW K  R +  SSRI   
Sbjct: 1561 VNEVLTVPEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFK 1618

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI 1007
                   +T+  + + D+G Y C A N  G ++ + NL +  KK I
Sbjct: 1619 SRDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 3/99 (3%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT-TMHDFGY 1767
            QAP FT  M  + V E      +   +  G PK  V+W R+G+P+    R++        
Sbjct: 1961 QAPSFTSEMSQVEVDEG--GEVKLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSSRVQG 2018

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
            V L ++ V   D G Y C   N+ G   T+  + V  ++
Sbjct: 2019 VTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS 2057



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 25/70 (35%), Positives = 39/70 (55%)

Query: 793  QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852
            ++T  ++P  +V WYKDG+  + + R+          L I + + ED+GSY   A NKLG
Sbjct: 2472 KVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLG 2531

Query: 853  EAISTASIRV 862
             A  + +IRV
Sbjct: 2532 FADKSFTIRV 2541



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+  + +K  EV EG    L   +T    PT  +EWY +  P++   R    +      L
Sbjct: 2847 PEIVQRLKACEVPEGSSFKLRCRVT--GTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFL 2904

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            + L   A D G YM  A N +G   T++ + ++
Sbjct: 2905 NFLETEARDEGRYMLVAKNHLGSVSTSAELIIE 2937



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 3/91 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P+ ++ L+   E+ EG +     ++T    PT  +EWYK   P+  + R+          
Sbjct: 2847 PEIVQRLKAC-EVPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQYF 2903

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
            LN +   A D G Y + A N LG   ++A +
Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAEL 2934



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 5/115 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F + ++  E  +G     E  ++    P  ++ W  +G+ +      K  YD     L
Sbjct: 3140 PEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKL 3197

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092
                   ED G Y C A+N  GEA + +S+ +     L +    E RLK I+ +E
Sbjct: 3198 TFYETQPEDEGDYTCVASNEAGEASSHASLVL--SKPLVMPEFKE-RLKNIKVVE 3249



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKT-INDFGFVI 3616
            PEF     ++ + E   A F  R+    +   +VEWF  GK + + +R  +   +     
Sbjct: 3236 PEFKERLKNIKVVEGDEAQFSVRV--KGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYT 3293

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
            L I  V   D G Y C A+N  G+   S +L VK R
Sbjct: 3294 LTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 36/116 (31%), Positives = 56/116 (48%), Gaps = 12/116 (10%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRF-KLTSDFGFVTLDLVDVYERD 2980
            ++VEG     +  V  K +P+ K+EW+  GK ++  +RF     +    TL + DV   D
Sbjct: 3246 KVVEGD--EAQFSVRVKGEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYTLTISDVAMED 3303

Query: 2981 SGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK-GTEGLE--KIQNLEDSLR 3033
             G Y C A N  G+      V C+ + ++ ER   P+  T+ LE   + N  D LR
Sbjct: 3304 FGTYKCVASNDAGK------VQCSGRLDVKERMVPPEISTDVLEGPALLNEGDDLR 3353



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 6/115 (5%)

Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            V +++ P P +I P+  + ++VEG+ + LE +V     P   +EW  +G+  ++      
Sbjct: 3423 VIESKKPAPLFIAPLH-DQEVVEGETIRLECRVRATPRP--MVEWKKDGRTFKEDYHIYT 3479

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNL-IERTQHP 3016
              D    TL +      D G Y C A NK G     S    T K+ L I    HP
Sbjct: 3480 EFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRG--RSVAQLTVKEALIIPHFDHP 3532



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 7/130 (5%)

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPV 508
            L I+  T+ D G  TC A N +G  +  C   +I    V AP  V++ +T      G  +
Sbjct: 5930 LCISCATIEDEGEYTCRASNPAGSCS--CTAELI----VDAPAKVDQAATPGSGVVGGKI 5983

Query: 509  VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
             L     G P P  TW +    +     + I T    S+L I R +  D   Y+   +N 
Sbjct: 5984 TLTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVKND 6043

Query: 569  AGSTATRARL 578
             G  +   +L
Sbjct: 6044 GGEDSCVVKL 6053



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 38/126 (30%), Positives = 56/126 (44%), Gaps = 7/126 (5%)

Query: 1540 TDIVRSTQ-NEAGLEQIQVLEDRSKYHRTD--MVDEVTTQAPICTTSLKNVEIKEGQRAH 1596
            T +++ T+  +AG  ++    D    H      V E +T+ P    SL++V    G+R  
Sbjct: 355  TLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERSTK-PEIEDSLRDVSALPGERVK 413

Query: 1597 FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPE-DSGTYTCRAI 1655
            F+ R+        KVEW      ++ G RFT       V   I+  L E D+G Y C A 
Sbjct: 414  FKVRI--GGKPKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVAT 471

Query: 1656 NALGEA 1661
            N  GEA
Sbjct: 472  NEAGEA 477



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 5/115 (4%)

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            E G      K + I    P+F T++K     E E V+ + +VE    PK  IEWYR   +
Sbjct: 668  ELGSAESKTKLKVIAFARPEFRTKLKPVKAVEGEEVQLDVKVEGY--PKPDIEWYRGTTM 725

Query: 3872 LPSGHRYRTVYDM---GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
            +    R++ + +    G  SL I  +  +D+G     A N  G+  ++A +  K+
Sbjct: 726  IVESGRFKVMEEEEEDGLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKE 780



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 9/162 (5%)

Query: 2216 GLEKIRQLEAQGHSTR---IEVEE--PKIS--PPRFVTELRGTTHVFEGKTAHFECQVEP 2268
            G+ K +   A G ++R   ++V++  PK +   P  + +L+    + EG TA+  C+V  
Sbjct: 1340 GVYKCQATNAAGSASRSWEVKVKQSAPKTTGEEPIIIRKLQAQ-EIDEGSTANLVCKVTA 1398

Query: 2269 VHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
               P   I++  +G  ++  +R  + FD    SL I+    +D G Y V   N  G  +S
Sbjct: 1399 AK-PEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASS 1457

Query: 2329 AISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEP 2370
               + V   GS     Q+ + +  I    +    K   +P P
Sbjct: 1458 TCRVLVNEVGSRPIFQQKLKAVSTIEGESTRFEVKLSAMPRP 1499



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 53/221 (23%), Positives = 88/221 (39%), Gaps = 41/221 (18%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            +F   L  +   EG++  FE  +     PT  +EWF ++  +  G R+            
Sbjct: 1471 IFQQKLKAVSTIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRF------------ 1516

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
             T T EE+SG+Y     ++  +   +G+ +     N+        GK   +A+ +  E  
Sbjct: 1517 -TITEEENSGVYVLVIEDT--NIEDAGTYKVVAYNNL--------GKVTSQALLRVNEVL 1565

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
                            PE++       +  EG  L L  +V  K  P+L  EW+   + L
Sbjct: 1566 TV--------------PEFMDKAEGPIEKTEGDDLELTVRVRGKPQPEL--EWFKYDRTL 1609

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
             + SR    S     T+ + D+   DSG+Y C A NK G +
Sbjct: 1610 WKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKAGSS 1650



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            ++EG T   +C +   G P   +EW+++      + R+  T D    S+T +  +  D+G
Sbjct: 1679 VKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDG 1736

Query: 2448 VYMCRASNLLG 2458
             Y C A+N LG
Sbjct: 1737 EYKCVATNPLG 1747



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 3/103 (2%)

Query: 902  VPESTQKPEFKTPIKDQ-ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT 960
            V E  Q P F      Q I +KEG   +  A +   G  +  V W KDGR V  S +  T
Sbjct: 1855 VIEKQQPPTFLGDDGTQTIIVKEGDDLNISATIA--GKPSPEVSWYKDGRLVLDSIKQET 1912

Query: 961  FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003
                    L + +  + DAG Y C A N +G  T + N+ +++
Sbjct: 1913 RKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKVMS 1955



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 4/102 (3%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            +L+  +N     E R  P  +    +EW+HN + +   SRV+         + +  V   
Sbjct: 2168 ELVQGDNYDLSLEVRGTPRPE----IEWYHNERLIYATSRVQLSFISSKATIALYNVTLD 2223

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKS 3667
            D+GLY CKA N  G  +    + V+ ++    EP + S  KS
Sbjct: 2224 DSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKS 2265



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            +P  + R + ++  IEG+ +  EC++    +    + W K+G      +R +   D    
Sbjct: 2550 EPTILQRLQPVDT-IEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFDGDVC 2606

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             L I D+   D GIY C A N  G+   S  LT
Sbjct: 2607 TLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELT 2639



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 6/98 (6%)

Query: 1171 EISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            E  KSK   P F + L     V +G     EC++   G P  ++ W  +G+ + +    K
Sbjct: 3131 EAKKSKGIIPEFFRQLRRVEAV-QGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIK 3187

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             +YD     L        D G+YT  A N  G A + A
Sbjct: 3188 PFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHA 3225



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 3/94 (3%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P  +QPL     V E +N  L C +   G PT   EW+ +   V    R K+    G  
Sbjct: 8    RPQILQPLEGVD-VKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMA 64

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
             L I    + D GEY     N  G+A + A + V
Sbjct: 65   TLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 6/117 (5%)

Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GY 827
           +P F   ++ + + +EG+   F+  +     P   V WYK    I    R   +     +
Sbjct: 103 KPSFTSKMKPV-DAEEGQEVRFDVHVK--GSPKPDVVWYKGSTMIGTHERFQIVEAAEDH 159

Query: 828 VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKT 884
           V+L I  ++ EDA +Y V A N +G+  S A +RV  R    A   I E+R  I+ T
Sbjct: 160 VTLVISEVKLEDAETYKVVATNDVGKVTSRADLRVKERQ--FAPEFIDEERGPIDAT 214



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 21/60 (35%), Positives = 31/60 (51%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T+EW  NG ++  + R +     G V L I + RA+D G YT + RN  G A+    + V
Sbjct: 621  TIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKV 680



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 3/98 (3%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            S+P F   +S P  V+EG     E R+E  G P ++VEWF     +    R+    D   
Sbjct: 1187 SRPEFKIKMS-PVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNR 1243

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
              + I + T  D G Y   A N  G   + A + V ER
Sbjct: 1244 YTMVIANVTLEDAGGYRCVATNTAGKTTSRADLTVKER 1281



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 36/148 (24%), Positives = 61/148 (41%), Gaps = 4/148 (2%)

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFS 1314
            V  +G +HT  IVR       V   Q   A        +   + KQ     T  + P   
Sbjct: 1320 VRAIGDSHTCFIVRAKLSDAGVYKCQATNAAGSASRSWEV--KVKQSAPK-TTGEEPIII 1376

Query: 1315 RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
            R L   E  EG+  +L C++     +   ++W  +G  I+   R +  ++ +  +L +  
Sbjct: 1377 RKLQAQEIDEGSTANLVCKVTAAKPEPS-IKWTRDGVKIRENSRIKMVFDGETCSLTIRD 1435

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRV 1402
               +D GVY    TN+ G A ++C + V
Sbjct: 1436 ATLDDEGVYKVTLTNEYGTASSTCRVLV 1463



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 2/116 (1%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  + +  I+  EG  +    RV   G P   ++WF   R     SR++  +      
Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFKSRDNKFT 1625

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810
            + +  +   D+G Y C A NK GS++ T  +    K+ I     +   +  +++KE
Sbjct: 1626 MTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVIGNAPDIITHLISKEVKE 1681



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 11/135 (8%)

Query: 3966 DVDKKQ----PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNR 4021
            DV KK+     P  +T + S+  + E  T   EC ++  G P   +EW+ +G       R
Sbjct: 1657 DVQKKKVIGNAPDIITHLISK-EVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRR 1713

Query: 4022 FTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHM 4081
                +D    ++ F      D GEY C ATN  G  ++ A +  T    +    +  + +
Sbjct: 1714 VMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTVT----VPSKPEFKQKL 1769

Query: 4082 KSIEKIREMEASWQV 4096
            + +E +   EA + V
Sbjct: 1770 RPLEVVEGSEAKFDV 1784



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 6/103 (5%)

Query: 2100 IEEEQPGQRPVFL-TALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158
            IE++QP   P FL    T    +KEGD  +    +     P   + W+ +G+ +    + 
Sbjct: 1856 IEKQQP---PTFLGDDGTQTIIVKEGDDLNISATIA--GKPSPEVSWYKDGRLVLDSIKQ 1910

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             T        L +     ED+G+Y C+A NKLG    T  +KV
Sbjct: 1911 ETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKV 1953



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 9/113 (7%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            ++ EG+   LE  V     P L  EWY +G  +++  R + T + G   L + + +  D 
Sbjct: 2267 EVKEGEQAELEFVVSGTPTPTL--EWYRDGLRVKESRRVRSTLENGIARLVITETWAEDM 2324

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRK 3034
            G Y C+  N  G   TS+ +      N+I  T+ P+  E L K++  E    K
Sbjct: 2325 GTYKCQVRNDLGRTSTSAHL------NIIVATR-PEFKEKLTKVEVTEGDRAK 2370



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 4/103 (3%)

Query: 2098 KPIEEEQPGQR-PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156
            KP    +PG+  P  +  L + E + EG      CRV     P  TI+W+ +   ++   
Sbjct: 2835 KPKRGLKPGEAAPEIVQRLKACE-VPEGSSFKLRCRVTGTPTP--TIEWYKSNMPLKPNG 2891

Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
            R    H      L+ L T A D G YM  A N LG    +  L
Sbjct: 2892 RVIIGHTGDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAEL 2934



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 10/143 (6%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG +    C V  +  PT  IEW+ +N PL    R    H      L+   T   D G Y
Sbjct: 2860 EGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDEGRY 2917

Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVE--QAEEARLAKGRRPSVP 2904
               A N  GS +TS  L       I      P  +  L AVE  + +E R     +    
Sbjct: 2918 MLVAKNHLGSVSTSAEL------IIEPSVSPPSFRHRLTAVEVDEGDETRFDVRLKKEPT 2971

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQ 2927
              E+ K +  I      +++EG+
Sbjct: 2972 SVEWYKEQQRIFTDGHFEVIEGE 2994



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 3/70 (4%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THDFGFVTLDINSVVANDAGL 2580
            EG  A +  RV   G+P  + EW+  G ++K  +RF +   +    TL I+ V   D G 
Sbjct: 3249 EGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTYTLTISDVAMEDFGT 3306

Query: 2581 YMCKAINRAG 2590
            Y C A N AG
Sbjct: 3307 YKCVASNDAG 3316



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 2/94 (2%)

Query: 2497 RSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSR 2556
            R +  +R     I T VL GP+ L EG        V   G+P    +WY +GV ++  + 
Sbjct: 3323 RLDVKERMVPPEISTDVLEGPALLNEGDDLRLVVSVT--GNPIPDLQWYKDGVLIRRSTH 3380

Query: 2557 FRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
               +      +L I  VV  D G+  C A+N AG
Sbjct: 3381 ISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAG 3414



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 2/84 (2%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            L EG  L L   V     PDL  +WY +G ++ + +   L+S     +L ++ V   D+G
Sbjct: 3346 LNEGDDLRLVVSVTGNPIPDL--QWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTG 3403

Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSK 3006
            +  C A N  G A  S TV   SK
Sbjct: 3404 VIKCVAMNPAGSASKSFTVVIESK 3427



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 4/112 (3%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI--KNSPDFQ-IHTF 4462
            +  + P+FT  ++   + + + ARF+    G P P + W RE+  I   + P  + +H  
Sbjct: 5123 RKEEAPVFTALLKDRTIKDGDAARFDARVIGFPTPDVTWLREDKQITPNSHPHMKALHEG 5182

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPP 4514
               S+LI    + +DS V+  +A+N  G      +L VE    +   G+  P
Sbjct: 5183 EVHSLLITEGGY-KDSGVYKCIAKNSAGQDTTVGHLFVEGPEFKPIKGVQKP 5233



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L  +  KE +N    C +  S  PT   EW+ ++  +    R KS       +L I  T 
Sbjct: 15   LEGVDVKEDENAILSCTI--SGTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTR 72

Query: 2840 EEDSGIYTCKATNSKGSATTSGSL 2863
             ED G Y C   N  G+AT+   L
Sbjct: 73   AEDQGEYKCVLRNEHGTATSKAPL 96



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 2/108 (1%)

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            A R   V+       AP F+  L ++  +EG    L C++   G     +EW     P+ 
Sbjct: 283  ASRAFDVKVKAPKGDAPSFTIDLTHVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVT 340

Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            T  R R  +E +   L +      D+G Y   A N  G A +   L+V
Sbjct: 341  TSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQV 388



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 3/71 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFV-TLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            P  K+EW     V+E G RF +  +   V +L + D+ E D+G Y C A N+ GEA   S
Sbjct: 422  PKPKVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEA--ES 479

Query: 3000 TVYCTSKDNLI 3010
                T  + LI
Sbjct: 480  MAQLTVNEELI 490



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 10/165 (6%)

Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLT 1074
            G  K+     + + + R + EVK  +  P F G  +G   + EG     + RV+   +  
Sbjct: 757  GTIKVVATNASGKATSRADLEVKEREFAPEFEGDEEGPIVVTEGNEVSIQLRVKANPNAD 816

Query: 1075 MTVEWYFNGKQITSANR--IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSAS 1132
              V+W+ +G+ I  + +  I+   +   +A+ ++S+  ED+GVY   A N  G+A  S  
Sbjct: 817  --VDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSL--EDTGVYKCEASNRLGKASRSFD 872

Query: 1133 MTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKP 1177
            + V+ +     + I   +  K R +E  +  E   +     K  P
Sbjct: 873  VKVQVKGPKGEAPI---ILSKLRPVETEEGEETKLKCTFTGKPAP 914



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GY 2433
            RP+F Q ++N++  + G+   F+ ++   G P   V + R  + I D  R +   +  G 
Sbjct: 2059 RPIFGQKMKNVEG-RIGEDVRFEIQV--EGTPVPAVTFHRESEQIYDGGRYSIVEEENGL 2115

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
              +TI + R ED G Y C A N  GE
Sbjct: 2116 FVLTIRNTRPEDAGEYQCIAVNGAGE 2141



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVA 1769
            P+F   MK++     +   FE ++   G P   V + R    I    R + + +  G   
Sbjct: 2060 PIFGQKMKNVEGRIGEDVRFEIQV--EGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFV 2117

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
            L ++   PED+G Y C A+N  GE  +   L V+ + ++
Sbjct: 2118 LTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI 2156



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 5/103 (4%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK--TY 1229
            I  ++P F + L+    V+EG     E R++  G P   VEW+H    +    RF+  + 
Sbjct: 2347 IVATRPEFKEKLTKVE-VTEGDRAKFEVRVK--GYPYPEVEWYHGSNRILDEDRFEIESV 2403

Query: 1230 YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             + G+ +L +      D G Y   AVN  G +   A + V ER
Sbjct: 2404 KETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 2446



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 9/129 (6%)

Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            R+EV +P    P  +  L+    + EG+    EC+V    +P   I +  +G    +  R
Sbjct: 2540 RVEVPKPTGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNR 2596

Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350
                FD    +L I+     D G Y   A N+ G   S+  +TV      +    RP  L
Sbjct: 2597 IKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTV------LEREARPRIL 2650

Query: 2351 EKIRELESA 2359
            EK+++++S+
Sbjct: 2651 EKLQDVDSS 2659



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 4/120 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P  +  LK   ++ EG S  F+ R       T T+EWY +   +    R+   H      
Sbjct: 2847 PEIVQRLKAC-EVPEGSS--FKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L+     A D G Y +VA+N  G    SA + +E   S   S  HR    +    +E++F
Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVS-PPSFRHRLTAVEVDEGDETRF 2962



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 3/100 (3%)

Query: 3274 PSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRT 3333
            P  P    P+ +++++ V +  EG  A     +     P   +EW  NG ++    R + 
Sbjct: 583  PKKPKGTAPEIVSELRPV-EATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKC 639

Query: 3334 FHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
                G V L I     ++ G+Y C+  N+LG   +K  LK
Sbjct: 640  DLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLK 679



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100
            P F+   +G  +  EG       RV  +PQ +L    EW+   + +  ++RI        
Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVRGKPQPEL----EWFKYDRTLWKSSRINFKSRDNK 1623

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
              + ++ +  +DSG+Y  VARN AG +  + ++ V+ +  I
Sbjct: 1624 FTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P  +T   S E V EG  V  EC +      N  +EW+K+G   T   R     D    +
Sbjct: 1668 PDIITHLISKE-VKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMTTFDGSVAS 1724

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            +   D    D G Y C A N +G+ + S RLT
Sbjct: 1725 VTFTDAQGFDDGEYKCVATNPLGSAQSSARLT 1756



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 7/134 (5%)

Query: 3682 REEITIEDEKPNPPRFTVEI-KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            R ++T+  EK  PP F  +     I V EG  ++    +   G P+  + W+ +GR    
Sbjct: 1850 RADLTVI-EKQQPPTFLGDDGTQTIIVKEGDDLNISATI--AGKPSPEVSWYKDGRLVLD 1906

Query: 3741 GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800
              +  T        L +      DAG Y C A NK G+ T T  +   +      E Q P
Sbjct: 1907 SIKQETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKVMSTAP---EGQAP 1963

Query: 3801 QGMSGEKIKELERG 3814
               S     E++ G
Sbjct: 1964 SFTSEMSQVEVDEG 1977



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 14/142 (9%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND-FGFI 3753
            P FT E+   ++V EGG V     +     PT++  W  +G P     R+   +     +
Sbjct: 1963 PSFTSEMSQ-VEVDEGGEVKLYFLISGYPKPTVK--WTRDGIPVFEDYRISMDSSRVQGV 2019

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
             L I  +   D G Y C   N+ GS TTT ++       IV +  + + + G+K+K +E 
Sbjct: 2020 TLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQV-------IVTQRSI-RPIFGQKMKNVE- 2070

Query: 3814 GRI-SDAPKEEPIVSTPPKFIT 3834
            GRI  D   E  +  TP   +T
Sbjct: 2071 GRIGEDVRFEIQVEGTPVPAVT 2092



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 3/91 (3%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-G 3885
            S  P F  ++K+      E VRFE +VE    P   + ++R  + +  G RY  V +  G
Sbjct: 2057 SIRPIFGQKMKNVEGRIGEDVRFEIQVEGTPVPA--VTFHRESEQIYDGGRYSIVEEENG 2114

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTK 3916
               L I     ED+GEY C AVN  GE  +K
Sbjct: 2115 LFVLTIRNTRPEDAGEYQCIAVNGAGEVTSK 2145



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEY 1917
            G+   +E ++E  P P   V ++   + +  G RY     + G   L I     ED+GEY
Sbjct: 2074 GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEY 2131

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C A+N  G+  S   L+V+ + +I
Sbjct: 2132 QCIAVNGAGEVTSKGYLHVEEELTI 2156



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 2/64 (3%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS--DFGFVTLDLVDVYERDSGIYTCKAYNK 2991
            +V  K  P  ++EWY     +    RF++ S  + G+ +L + +V + D+G+Y C A NK
Sbjct: 2372 EVRVKGYPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNK 2431

Query: 2992 RGEA 2995
             G++
Sbjct: 2432 AGKS 2435



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 2/98 (2%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP     LK  E+ EG  + F+ R       T  +EWY +N PLK   R    +      
Sbjct: 2846 APEIVQRLKACEVPEG--SSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674
            L+ +     D G Y   A N LG   TS   I+    S
Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVS 2941



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 36/135 (26%), Positives = 58/135 (42%), Gaps = 10/135 (7%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S TVD    +++ G  PEF      +   + S+A FEC++        ++ W  +GK L 
Sbjct: 3125 SFTVDVEAKKSK-GIIPEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELA 3181

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL 3661
                +K   D     L        D G YTC A+N  GEA+    L       ++ +P +
Sbjct: 3182 IPRYIKPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASL-------VLSKPLV 3234

Query: 3662 PSHFKSGTESIQKLE 3676
               FK   ++I+ +E
Sbjct: 3235 MPEFKERLKNIKVVE 3249



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 40/125 (32%), Positives = 52/125 (41%), Gaps = 6/125 (4%)

Query: 3529 EGTIDKIAA-LEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDS 3587
            EG  + IA   EG   +V  LT + E+   P F     DL + E   A F   +      
Sbjct: 3498 EGAYECIAKNKEGRGRSVAQLTVK-EALIIPHFDHPIQDLDVIEGDRAKFHVEVS--GKP 3554

Query: 3588 SMRVEWFHNGKPLLTGSRVKTIND--FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSC 3645
            + +VEW    + L  G RV    D       L I      D+G YTC A N+ GE T   
Sbjct: 3555 AAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSGKYTCIARNKAGENTCHG 3614

Query: 3646 KLQVK 3650
            +L VK
Sbjct: 3615 RLAVK 3619



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 7/130 (5%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHD--FGY 1100
            P F  P++  + ++EG  A F   VE        VEW    +++ +  R+    D     
Sbjct: 3527 PHFDHPIQDLD-VIEGDRAKFH--VEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEES 1160
              L I + +  DSG YT +ARN AGE      + V  +  + T S   G  ++   + E 
Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAV--KEKMVTPSFAEGDADEPCEVWEG 3641

Query: 1161 KFVEPMYQIE 1170
              ++ + QI+
Sbjct: 3642 APIKLIVQIK 3651



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 5/98 (5%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFGL 2699
            P F   ++  D ++EG       +V  +  P  K+EW K    L  G R  L+   +  +
Sbjct: 3527 PHFDHPIQDLD-VIEGDRAKFHVEVSGK--PAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
              L+I + +  DSG YTC A N  GE      + ++++
Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGENTCHGRLAVKEK 3621



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 19/67 (28%), Positives = 31/67 (46%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P   W+R +  +K+     I T   +S L I ++   D   +  V +N GG   C 
Sbjct: 5991 GNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVKNDGGEDSCV 6050

Query: 4496 ANLVVEE 4502
              L V++
Sbjct: 6051 VKLTVDD 6057



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 2/69 (2%)

Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            EG  A   C +   G P   +EW +N   ++DS R       G V +TI   R +D+G Y
Sbjct: 604  EGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDY 661

Query: 2450 MCRASNLLG 2458
             C   N LG
Sbjct: 662  TCIVRNELG 670



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 2/78 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            IV  EG+ +  +  V+ +  P   ++WF + +P+   T+          +L I  +  ED
Sbjct: 795  IVVTEGNEVSIQLRVKAN--PNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLED 852

Query: 2843 SGIYTCKATNSKGSATTS 2860
            +G+Y C+A+N  G A+ S
Sbjct: 853  TGVYKCEASNRLGKASRS 870



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 5/98 (5%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            +PE+ I ++   ++ EG     E +VE    P L++EW+     +E   R+  T+D    
Sbjct: 1188 RPEFKIKMSPV-EVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRY 1244

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
            T+ + +V   D+G Y C A N  G+  T+S    T K+
Sbjct: 1245 TMVIANVTLEDAGGYRCVATNTAGK--TTSRADLTVKE 1280



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 22/68 (32%), Positives = 36/68 (52%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G+P   ++W ++GV I  S  ++        +L +  V PED+G   C A+N  G A  S
Sbjct: 3360 GNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKS 3419

Query: 1798 STLFVQSK 1805
             T+ ++SK
Sbjct: 3420 FTVVIESK 3427



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 23/59 (38%), Positives = 28/59 (47%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +EWLK   PV  S R+ T F      L IK   + DAG Y   A N  G A + A L +
Sbjct: 330  IEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQV 388



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+    ++DV+ L  G+   F+ R+     P  KVEW      +  G R+    +   V 
Sbjct: 395  PEIEDSLRDVSAL-PGERVKFKVRIGGKPKP--KVEWRKGKSVIEDGERFTIAEESDEVF 451

Query: 3342 LDILYCYEE-NSGEYECVATNKLGRDSTKANLKCTSKENLI 3381
              I+   EE ++G Y+CVATN+ G   + A L  T  E LI
Sbjct: 452  SLIIQDLEETDAGRYKCVATNEAGEAESMAQL--TVNEELI 490



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 5/112 (4%)

Query: 3403 SMVRRKDTSVEEEK--GKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
            S  R  +  V+++K  G AP     L + E ++EG     E  ++    PN  +EWY +G
Sbjct: 1649 SSSRTFNLDVQKKKVIGNAPDIITHLISKE-VKEGGTVTLECTVSGKPAPN--IEWYKDG 1705

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
                A  R  T  D     +  +     D GEY C A N  G A ++A + V
Sbjct: 1706 LRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 8/143 (5%)

Query: 902  VPESTQKPEFKT-PIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT 960
            V E    PEF+T   +  I + EGG    +  L    +   +V W KDG+    + R+  
Sbjct: 2443 VNERQFAPEFETGEERGPIVVPEGGETTLKVTLR--ANPKPQVIWYKDGKHTSENIRLDV 2500

Query: 961  FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020
                    L I +  + D+G Y C A N +G A  S  + +   K      + P  L+++
Sbjct: 2501 RSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADKSFTIRVEVPK---PTGEEPTILQRL 2557

Query: 1021 QYLEDASRYSKRTEEEVKITQKP 1043
            Q ++      +  + E +++ KP
Sbjct: 2558 QPVDTIE--GEAIKMECRVSGKP 2578



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 2/91 (2%)

Query: 2916 PIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVD 2975
            P    ++L EG  + L+  V  K +P  +I WY +  +  +  +  L+      +L L  
Sbjct: 3045 PDHGSYELQEGDTITLDAVV--KGNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYH 3102

Query: 2976 VYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            V  +DSG+Y C   NK G A  S TV   +K
Sbjct: 3103 VIPKDSGVYKCVLKNKVGTATKSFTVDVEAK 3133



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 3/101 (2%)

Query: 2234 VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI 2293
            V E K   P F+  L     V EG+T   EC+V     P   +E+  +G+  +     + 
Sbjct: 3423 VIESKKPAPLFIAPLHDQ-EVVEGETIRLECRVRAT--PRPMVEWKKDGRTFKEDYHIYT 3479

Query: 2294 TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             FD  + +L I+    ED G Y   A N  G   S   +TV
Sbjct: 3480 EFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTV 3520



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 2/92 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            PQ  + L  ++  E  N  L C +   G  T   EW+ +   ++   R +         L
Sbjct: 9    PQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATL 66

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +     ED G Y C   N+ G A +   L V
Sbjct: 67   TIKQTRAEDQGEYKCVLRNEHGTATSKAPLNV 98



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 10/129 (7%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            ++ ++PK + P  V+ELR      EG  A   C +     P   IE+  NG  ++ + R 
Sbjct: 581  VQPKKPKGTAPEIVSELR-PVEATEGDDAVLSCTISGKPVPT--IEWLKNGIRVKDSRRT 637

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
                  G V L I+    +D G+Y+    N LG   S   + V A         RPE   
Sbjct: 638  KCDLVDGEVKLTIKTTRADDQGDYTCIVRNELGSAESKTKLKVIA-------FARPEFRT 690

Query: 2352 KIRELESAE 2360
            K++ +++ E
Sbjct: 691  KLKPVKAVE 699



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 1435 IIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494
            ++   V  +P F  + K++ + IEG+   FE KL  +      VEWFK+   +  G RF 
Sbjct: 1461 VLVNEVGSRPIFQQKLKAV-STIEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFT 1517

Query: 1495 PIHD--FGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
               +   G   L I D   ED+G Y   A N +G
Sbjct: 1518 ITEEENSGVYVLVIEDTNIEDAGTYKVVAYNNLG 1551



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 6/97 (6%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF--- 2164
            +P F   L  LE + EG  A F+ R++    P   ++W+    KI    R++ T  +   
Sbjct: 1762 KPEFKQKLRPLE-VVEGSEAKFDVRIKSYPKPE--VEWYRGTTKITDSLRHQITEPYEGD 1818

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               +L IL T  ED+  Y C A N+ G+      L V
Sbjct: 1819 DTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTV 1855



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 6/96 (6%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHN-GQKIRAGHRYRTTHDF-G 2165
            RP+F   + ++E  + G+   FE +VE    P +T   FH   ++I  G RY    +  G
Sbjct: 2059 RPIFGQKMKNVEG-RIGEDVRFEIQVEGTPVPAVT---FHRESEQIYDGGRYSIVEEENG 2114

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               L I  T  ED+G Y C A N  GE  +   L V
Sbjct: 2115 LFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHV 2150



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 3/90 (3%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-L 2833
            +F   + N+  + G+++ FE  VE +  P   + +   ++ +  G RY    + + +  L
Sbjct: 2061 IFGQKMKNVEGRIGEDVRFEIQVEGT--PVPAVTFHRESEQIYDGGRYSIVEEENGLFVL 2118

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I +T  ED+G Y C A N  G  T+ G L
Sbjct: 2119 TIRNTRPEDAGEYQCIAVNGAGEVTSKGYL 2148



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF-GYVSLDIQHCVPEDAGEY 2315
            G+   FE QVE    P   + F+   + +    R+ I  +  G   L I++  PEDAGEY
Sbjct: 2074 GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEY 2131

Query: 2316 SVKAINALGHCTS 2328
               A+N  G  TS
Sbjct: 2132 QCIAVNGAGEVTS 2144



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 3/101 (2%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            V +  G+ P     L  ++ + EGE    E R++   +P   + W  +G      +R +T
Sbjct: 2543 VPKPTGEEPTILQRLQPVDTI-EGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKT 2599

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            + D     L I      D G Y C A N+ G A ++A + V
Sbjct: 2600 YFDGDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTV 2640



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT--SIFNFGY 827
            P F  P+QDL ++ EG  A F  +++    P  +VEW K  + +    R++         
Sbjct: 3527 PHFDHPIQDL-DVIEGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSLEEDRETQM 3583

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGE 853
              L I + +  D+G YT  A NK GE
Sbjct: 3584 YFLTITNCKPTDSGKYTCIARNKAGE 3609



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 2/80 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  GK+T   C ++G P P  TWF  D +++      I   +    +L I  +   D G 
Sbjct: 5978 VVGGKIT-LTCLISGNPVPTATWFRGDEELKSGGRIHIETTDD-RSSLTIERIQFRDEGE 6035

Query: 463  VTCVARNKSGETAFQCRLNV 482
               V +N  GE +   +L V
Sbjct: 6036 YELVVKNDGGEDSCVVKLTV 6055



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVA 1769
            P FT  MK +   E Q   F+  +   G PK  V W +    I    R   +     +V 
Sbjct: 104  PSFTSKMKPVDAEEGQEVRFDVHV--KGSPKPDVVWYKGSTMIGTHERFQIVEAAEDHVT 161

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            L +  V  ED+ TY   A N++G+  + + L V+ +
Sbjct: 162  LVISEVKLEDAETYKVVATNDVGKVTSRADLRVKER 197



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 5/129 (3%)

Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAV--NQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            ++AL K +      +  R  DV+V      AP F   L    +  EG+ +   C++   P
Sbjct: 268  DTALYKCEAENKLGKASRAFDVKVKAPKGDAPSFTIDLTH-VRAIEGEESKLVCKVTGKP 326

Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
             P   +EW      + +  R RT  +   A L I      D+G Y   A N+ G A S  
Sbjct: 327  APT--IEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIA 384

Query: 1933 RLNVQSKES 1941
             L VQ + +
Sbjct: 385  ELQVQERST 393



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 5/110 (4%)

Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737
            T H   E+ ++ E+   P     ++D   +P G  V F  R+   G P  +++W      
Sbjct: 379  TAHSIAELQVQ-ERSTKPEIEDSLRDVSALP-GERVKFKVRIG--GKPKPKVEWRKGKSV 434

Query: 3738 FATGSRVHTLNDFGFI-ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
               G R     +   + +L I  +   DAG Y C ATN+ G A + A++T
Sbjct: 435  IEDGERFTIAEESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLT 484



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 36/156 (23%), Positives = 68/156 (43%), Gaps = 12/156 (7%)

Query: 1275 IVTDTQNEQAIEQIQLLEDAARRTKQVREDITVM---QAPQF--SRALHNIETVEGTNVH 1329
            I+  T  + A+ +     +A + T   R D+TV+   Q P F        I   EG +++
Sbjct: 1825 ILNTTMEDAAMYKCVAFNEAGKTT--CRADLTVIEKQQPPTFLGDDGTQTIIVKEGDDLN 1882

Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN 1389
            +   +   G  +  V W+ +G+ +    +       D   L + +   ED+G Y C+A N
Sbjct: 1883 ISATI--AGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAGSYKCEANN 1940

Query: 1390 QLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
            +LG    +  ++V++      E Q PS   ++  +E
Sbjct: 1941 KLGTVTKTYNVKVMSTAP---EGQAPSFTSEMSQVE 1973



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 4/113 (3%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            I  Q S RP F + ++++ E + G +  FE Q+     P   V ++++   I    R + 
Sbjct: 2052 IVTQRSIRPIFGQKMKNV-EGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSI 2108

Query: 822  IFNF-GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLG 873
            +    G   L I + R EDAG Y   AVN  GE  S   + V    T+   +G
Sbjct: 2109 VEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTIPQFIG 2161



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 18/53 (33%), Positives = 27/53 (50%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            P  +     V   EGE  +  CRV+G P+P + WL +G   +  +R K  +DG
Sbjct: 2551 PTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTYFDG 2603



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 3/116 (2%)

Query: 637  PQFI-VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P FI +  + +TA EG  I     ++  G P   +E+LK+   +  S R          +
Sbjct: 2744 PSFIGIEFEPITAYEGSDIDLTFYVK--GRPLPTVEFLKDEVPVFKSDRTELTSNGNRHT 2801

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751
            L +  L ++DS  Y   A +  GVA     L V P+  ++     PE +Q ++  E
Sbjct: 2802 LYLSDLAVRDSATYKAVAKNKAGVARRSVELLVKPKRGLKPGEAAPEIVQRLKACE 2857



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+ +  LK+    EG    F+ R    G PT  IEW K+   ++ + R           L
Sbjct: 2847 PEIVQRLKACEVPEGSS--FKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFL 2904

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTP 730
            + L    +D G Y   A +  G   T A L + P
Sbjct: 2905 NFLETEARDEGRYMLVAKNHLGSVSTSAELIIEP 2938



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 4/97 (4%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV- 828
            P+F   L+++ ++ EG  A F  ++    +P  +VEW+K G+ I + +R +S     +  
Sbjct: 3236 PEFKERLKNI-KVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            +L I  +  ED G+Y   A N  G+   +  + V  R
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 38/150 (25%), Positives = 58/150 (38%), Gaps = 14/150 (9%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I    +ED   +   A N  G+  C+A L+V+   +  +    P S         V  
Sbjct: 5930 LCISCATIEDEGEYTCRASNPAGSCSCTAELIVDAPAKVDQAA-TPGS--------GVVG 5980

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G++  L   ++G       W +  ++++   R  I   D   +L I     +D G+YE V
Sbjct: 5981 GKIT-LTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELV 6039

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTK 4617
              N  GE      CVV L    D    Q K
Sbjct: 6040 VKNDGGE----DSCVVKLTVDDDSGDMQMK 6065



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYA 3762
            + +DV E       C +   G PT   +W+ +        R+ +    G   L I    A
Sbjct: 16   EGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTRA 73

Query: 3763 RDAGEYTCRATNKWGSATTTAKI 3785
             D GEY C   N+ G+AT+ A +
Sbjct: 74   EDQGEYKCVLRNEHGTATSKAPL 96



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 35/141 (24%), Positives = 58/141 (41%), Gaps = 5/141 (3%)

Query: 1264 SAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETV 1323
            S +V  +    I      +Q   +  L  +    T +   ++ V   P F+  +  ++  
Sbjct: 57   SEVVNGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVPVKPSFTSKMKPVDAE 116

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYVALDLLSVYPEDSG 1381
            EG  V  +  ++  G     V W+     I T  RF+   A E D+V L +  V  ED+ 
Sbjct: 117  EGQEVRFDVHVK--GSPKPDVVWYKGSTMIGTHERFQIVEAAE-DHVTLVISEVKLEDAE 173

Query: 1382 VYTCQATNQLGEAVTSCALRV 1402
             Y   ATN +G+  +   LRV
Sbjct: 174  TYKVVATNDVGKVTSRADLRV 194



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 4/100 (4%)

Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
           ++ S +P+    L+D+  L  G    F+ ++     P  +VEW K    I    R T   
Sbjct: 389 QERSTKPEIEDSLRDVSALP-GERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAE 445

Query: 824 NFGYV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               V SL I  L   DAG Y   A N+ GEA S A + V
Sbjct: 446 ESDEVFSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV-TLSINSLRNDDSGIY 2715
            G+ V  + ++  +  P  K+EW K    +  G R     +   V +L I  L   D+G Y
Sbjct: 409  GERVKFKVRIGGKPKP--KVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEETDAGRY 466

Query: 2716 TCKATNLLGEAVSTASIKIED 2736
             C ATN  GEA S A + + +
Sbjct: 467  KCVATNEAGEAESMAQLTVNE 487



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 21/56 (37%), Positives = 34/56 (60%), Gaps = 2/56 (3%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            G P  ++EWF+ ++ +  SSRI  K+ D  + +MT+S +  +D G+Y C A N  G
Sbjct: 1594 GKPQPELEWFKYDRTLWKSSRINFKSRDNKF-TMTVSDLGLDDSGMYQCVARNKAG 1648



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 4/112 (3%)

Query: 2914 IIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDL 2973
            II      ++ EG  + LE  V  K  P+  IEWY +G       R   T D    ++  
Sbjct: 1670 IITHLISKEVKEGGTVTLECTVSGKPAPN--IEWYKDGLRFTATRRVMTTFDGSVASVTF 1727

Query: 2974 VDVYERDSGIYTCKAYNKRGEAFTSS--TVYCTSKDNLIERTQHPKGTEGLE 3023
             D    D G Y C A N  G A +S+  TV   SK    ++ +  +  EG E
Sbjct: 1728 TDAQGFDDGEYKCVATNPLGSAQSSARLTVTVPSKPEFKQKLRPLEVVEGSE 1779



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPS-GHRYRTVYD 3883
            V + P+F  +++   V E    +F+ R+  K  PK  +EWYR   K+  S  H+    Y+
Sbjct: 1759 VPSKPEFKQKLRPLEVVEGSEAKFDVRI--KSYPKPEVEWYRGTTKITDSLRHQITEPYE 1816

Query: 3884 -MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
                 SL IL    ED+  Y C A N+ G+   +A ++
Sbjct: 1817 GDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLT 1854



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 37/145 (25%), Positives = 59/145 (40%), Gaps = 13/145 (8%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P+ E P  + ++Q V   +EG++   E R+    +P   + W  +G      +R +T+ D
Sbjct: 2546 PTGEEPTILQRLQPVDT-IEGEAIKMECRVSGKPEPT--ITWLKDGLVFLTDNRIKTYFD 2602

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK 3396
              +  L I      + G Y C A N  G   + A L    +E        PR     LEK
Sbjct: 2603 GDVCTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLERE------ARPR----ILEK 2652

Query: 3397 LQTLEDSMVRRKDTSVEEEKGKAPV 3421
            LQ ++ S+  R    +       PV
Sbjct: 2653 LQDVDSSVGERAMFKIRVSGSPMPV 2677



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR-IQTYHDFGY 1100
            +PR L  L+  +  V G+ A F+ RV         V+WY   ++IT+    I      GY
Sbjct: 2646 RPRILEKLQDVDSSV-GERAMFKIRVSGSP--MPVVQWYRRDEEITTKGHYIVRDEGRGY 2702

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSA 1131
             +L I  +  ED G Y  V  N +GE   +A
Sbjct: 2703 FSLTIEYIDYEDEGAYKAVVINDSGEVSSTA 2733



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYV 1775
            ++D+  +  + A F+ R+   G P   V+W R    I          +  GY +L ++Y+
Sbjct: 2653 LQDVDSSVGERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFSLTIEYI 2710

Query: 1776 NPEDSGTYTCRAINELGEAVTSSTL 1800
            + ED G Y    IN+ GE  +++ L
Sbjct: 2711 DYEDEGAYKAVVINDSGEVSSTAVL 2735



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 3/99 (3%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP  + +L    ++ EG S    CR+   P P   +EWY +   L+   R    +     
Sbjct: 2846 APEIVQRLKA-CEVPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQY 2902

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
             L+ L     D G Y   A N+LG   +S  L ++   S
Sbjct: 2903 FLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVS 2941



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 2/77 (2%)

Query: 3710 GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYT 3769
            GG +   C +   G+P     WF       +G R+H        +L I+ I  RD GEY 
Sbjct: 5980 GGKITLTCLIS--GNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYE 6037

Query: 3770 CRATNKWGSATTTAKIT 3786
                N  G  +   K+T
Sbjct: 6038 LVVKNDGGEDSCVVKLT 6054



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 2/102 (1%)

Query: 3551 EAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN 3610
            +A  G+ P FT   + +   E   +   C++      +  +EW     P+ T  RV+T  
Sbjct: 292  KAPKGDAPSFTIDLTHVRAIEGEESKLVCKV--TGKPAPTIEWLKGELPVTTSLRVRTDF 349

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
            +     L I      DAG Y   A N  G A    +LQV+ R
Sbjct: 350  EKNVATLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQER 391



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 2/109 (1%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F        + E  S     R+      +  +EW  +GK +   + V T       +L
Sbjct: 492  PRFEKMKESFTVVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVL 549

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
             I    + D+GLY C A N+ G A ++ +L V+ ++     P++ S  +
Sbjct: 550  TIEESSRDDSGLYRCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELR 598



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 6/112 (5%)

Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223
            E   +++ I+ ++P F   L  P    EG+ + L+ ++E  G P   +EW+     +   
Sbjct: 673  ESKTKLKVIAFARPEFRTKLK-PVKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVES 729

Query: 1224 SRFKTY---YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             RFK      + G  +L I      DTG   V A N  G A + A + V ER
Sbjct: 730  GRFKVMEEEEEDGLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKER 781



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 20/64 (31%), Positives = 29/64 (45%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   +EW+ +G +     R  T  D  +  +        + GEY+CVATN LG   + A 
Sbjct: 1695 PAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLGSAQSSAR 1754

Query: 3372 LKCT 3375
            L  T
Sbjct: 1755 LTVT 1758



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 3/95 (3%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYV 2035
            +P FG+ +KN E   G  V  E  +     P   V ++     +  G R+    +  G  
Sbjct: 2059 RPIFGQKMKNVEGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSIVEEENGLF 2116

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             L I     ED G Y C A N  GE  +   + V+
Sbjct: 2117 VLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVE 2151



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 4/96 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF-GLV 2700
            PIF   +K+ +  + G+ V  E QVE    P   + + +    +  G R     +  GL 
Sbjct: 2060 PIFGQKMKNVEGRI-GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLF 2116

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             L+I + R +D+G Y C A N  GE  S   + +E+
Sbjct: 2117 VLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEE 2152



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 7/125 (5%)

Query: 1820 KIQQLEDSSRYQRREDVEVAVNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNM 1876
            K   L +S +   R   E+ VN+    P F    +G  +L EG +   +  ++  P P +
Sbjct: 3015 KCTALNESGKSSTR--AELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVKGNPYPEI 3072

Query: 1877 RVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            R  WY +  +     +   S      +L +  V  +DSG Y C   N +G A  S  ++V
Sbjct: 3073 R--WYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDV 3130

Query: 1937 QSKES 1941
            ++K+S
Sbjct: 3131 EAKKS 3135



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY--DGMYHFD 4168
            P F+     + + EG  AR C RV G P+P + W  +   I  G R +  +  DG+    
Sbjct: 3735 PSFLQRMQDLEIVEGSAARLCVRVQGVPEPEIDWYKDNRVIREGGRVEFEFEEDGLCMLV 3794

Query: 4169 IPKTRQYDTGKIEVI 4183
            I    + D G+ + +
Sbjct: 3795 IRDATKSDRGRYKCV 3809



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 2/80 (2%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G + +F  +    P P V+W +   PL    +Y +      G  SL IK     D G Y
Sbjct: 4114 EGMSVRFNCRTTSQPKPYVTWFKDGQPLASYGRYEV--TSVAGAQSLTIKDCKLADAGIY 4171

Query: 145  TCTARNQYGEAICSVYIQPE 164
             C   N  G+A  S ++  E
Sbjct: 4172 KCEVSNVGGKAGTSAHLTVE 4191



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+   PL+SV   EG     E  +   G P+  +EW K+   +  S R           L
Sbjct: 1094 PKITKPLESVEVNEGEDFDLECVVS--GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKL 1151

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
                   +D GEY C  ++  G A T   + V
Sbjct: 1152 VFKQARPEDIGEYKCTVINEHGKASTTGEVKV 1183



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAG 3628
            + E S+A+  C++         ++W  +G  +   SR+K + D     L I      D G
Sbjct: 1384 IDEGSTANLVCKVTAAKPEPS-IKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEG 1442

Query: 3629 LYTCKATNRHGEATVSCKLQV 3649
            +Y    TN +G A+ +C++ V
Sbjct: 1443 VYKVTLTNEYGTASSTCRVLV 1463



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 8/112 (7%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S R+ V  P  S P F  +LR    V EG  A F+ +++    P   +E+Y     +  +
Sbjct: 1752 SARLTVTVP--SKPEFKQKLR-PLEVVEGSEAKFDVRIKSYPKPE--VEWYRGTTKITDS 1806

Query: 2289 ARFHITFDF---GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             R  IT  +      SL I +   EDA  Y   A N  G  T    +TV  K
Sbjct: 1807 LRHQITEPYEGDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK 1858



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 20/89 (22%), Positives = 45/89 (50%), Gaps = 4/89 (4%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFGLVTLSINSLRND 2710
            ++ EG     E +V+    P  ++EW+     +    R  ++S  + G  +L++  +  +
Sbjct: 2362 EVTEGDRAKFEVRVKGYPYP--EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQE 2419

Query: 2711 DSGIYTCKATNLLGEAVSTASIKIEDRHW 2739
            D+G+Y C A N  G++   A +++ +R +
Sbjct: 2420 DAGMYKCIAVNKAGKSTCRADLEVNERQF 2448



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 47/231 (20%), Positives = 81/231 (35%), Gaps = 20/231 (8%)

Query: 3983 TSLVEMET-TKFECQLAPVGDPNM--KVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVY 4039
            T L  ME  +  +  L  +  P    K+EWF + + +  + RFT   +     +      
Sbjct: 4888 TPLANMEVFSGDDVMLEVISGPEQVKKIEWFKDNELIRDRPRFTVTSEDTRHTLTIATAT 4947

Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPE 4099
             +D G + C   N +G+    A I          +S   +      +I    +   +   
Sbjct: 4948 FDDEGIFKCVLLNDFGIASCSAEILVEEDEESYSESSADEATDRNARIERRRSRDSICAL 5007

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            +  +E K R             V +G+   F  R+TG P+P+V+W  +   +V   R   
Sbjct: 5008 EFQQELKDR------------EVLDGDTIHFDVRITGRPEPKVVWYKDDKELVESKRIIF 5055

Query: 4160 TYD---GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV--IPRHDD 4205
              +   G+Y   I K    D G    +             L V  +P  +D
Sbjct: 5056 VSEPETGLYSLLIKKATLDDEGDYRCVAANPAGTISCQAELLVEDVPEEED 5106



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 37/131 (28%), Positives = 49/131 (37%), Gaps = 5/131 (3%)

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739
            L IS A  EDEG+Y C A N AG  +  A+L V  P + D   A TP   +V   G    
Sbjct: 5930 LCISCATIEDEGEYTCRASNPAGSCSCTAELIVDAPAKVDQ--AATPGSGVV---GGKIT 5984

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
                I+    PT  W R    +       +    + + L I      D G +        
Sbjct: 5985 LTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVKNDG 6044

Query: 4800 GQVETSAKLVV 4810
            G+     KL V
Sbjct: 6045 GEDSCVVKLTV 6055



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 9/117 (7%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            ++W +DG  +  +SRI   F+    +LTI+  T+ D G Y     N  G A+++  + + 
Sbjct: 1405 IKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLV- 1463

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPR-FLGPLKGTNKIVEG 1058
               ++ +       L+ +  +E  S     T  EVK++  PR  +   K +++I +G
Sbjct: 1464 --NEVGSRPIFQQKLKAVSTIEGES-----TRFEVKLSAMPRPTVEWFKSSSQIYDG 1513



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 2/83 (2%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT 2567
            P F     GP E  EG       RV   G P    EW+     L   SR          T
Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFKSRDNKFT 1625

Query: 2568 LDINSVVANDAGLYMCKAINRAG 2590
            + ++ +  +D+G+Y C A N+AG
Sbjct: 1626 MTVSDLGLDDSGMYQCVARNKAG 1648



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 12/112 (10%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT--IGHRF-RP 1495
            +V  KP F  + + +E V+EG    F+ +++       +VEW++    +T  + H+   P
Sbjct: 1758 TVPSKPEFKQKLRPLE-VVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITEP 1814

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
                   +L I++   ED+ +Y C A N  G      + TCR+   ++   Q
Sbjct: 1815 YEGDDTYSLIILNTTMEDAAMYKCVAFNEAG------KTTCRADLTVIEKQQ 1860



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 36/127 (28%), Positives = 54/127 (42%), Gaps = 4/127 (3%)

Query: 1012 QHPGGLEKIQYLEDASRYSKRTEEEVKITQ-KPRF-LGPLKGTNKIVEGQSAHFEARVEP 1069
            Q   G+ K   +  A + + R + EV   Q  P F  G  +G   + EG       +V  
Sbjct: 2418 QEDAGMYKCIAVNKAGKSTCRADLEVNERQFAPEFETGEERGPIVVPEGGETTL--KVTL 2475

Query: 1070 QSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQL 1129
            +++    V WY +GK  +   R+          L I + + EDSG Y   ARN  G A  
Sbjct: 2476 RANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFADK 2535

Query: 1130 SASMTVE 1136
            S ++ VE
Sbjct: 2536 SFTIRVE 2542



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 5/105 (4%)

Query: 3680 HKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA 3739
            H   E+T+ + +  P R   +++D +D   G    F  RV   G P   + W+       
Sbjct: 2633 HSSAELTVLEREARP-RILEKLQD-VDSSVGERAMFKIRVS--GSPMPVVQWYRRDEEIT 2688

Query: 3740 T-GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
            T G  +      G+ +L I+YI   D G Y     N  G  ++TA
Sbjct: 2689 TKGHYIVRDEGRGYFSLTIEYIDYEDEGAYKAVVINDSGEVSSTA 2733



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            PE    +K    + EG  + F+ R    G  T  +EW K   P++ + R+          
Sbjct: 2847 PEIVQRLK-ACEVPEG--SSFKLRCRVTGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L        D G Y   A N +G  +TSA L I
Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAELII 2936



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   Q L+  + + EG +    CR+   G PT  +EW+++   ++ + R+   H      
Sbjct: 2847 PEIVQRLKACE-VPEGSSFKLRCRV--TGTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYF 2903

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            +        DEG YM  A N LG
Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLG 2926



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F  P     ELQEG     +A +    +P   + WYKD      S ++         S
Sbjct: 3040 PGFEGPDHGSYELQEGDTITLDAVVK--GNPYPEIRWYKDEFLAMESKKLMLSVRDRKNS 3097

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARST 867
            L + H+  +D+G Y     NK+G A  + ++ V A+ +
Sbjct: 3098 LTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKS 3135



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 18/63 (28%), Positives = 33/63 (52%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            ++WY +   ++  +  + ++     +L IM  +PED+G   C A+N  G A  S   ++ 
Sbjct: 3366 LQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIE 3425

Query: 1671 SKK 1673
            SKK
Sbjct: 3426 SKK 3428



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 4/83 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD-VS 130
            P+F     +    +G   + E ++R  P P+V W +      E   Y + Y E  G   +
Sbjct: 3431 PLFIAPLHDQEVVEGETIRLECRVRATPRPMVEWKKDGRTFKE--DYHI-YTEFDGQHCT 3487

Query: 131  LLIKQIGPGDEGEYTCTARNQYG 153
            L+IK     DEG Y C A+N+ G
Sbjct: 3488 LVIKGAQIEDEGAYECIAKNKEG 3510



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            +FI+ L++    EG+ I  EC V  +  P   +EW  + +         +  D  + +L 
Sbjct: 3432 LFIAPLHDQEVVEGETIRLECRVRATPRPM--VEWKKDGRTFKEDYHIYTEFDGQHCTLV 3489

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I     ED G Y C A N +G   +   L
Sbjct: 3490 IKGAQIEDEGAYECIAKNKEGRGRSVAQL 3518



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 20/88 (22%), Positives = 37/88 (42%), Gaps = 1/88 (1%)

Query: 1447 VTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDI 1506
            + R    + + EG   +  CK+         ++W ++G  +    R + + D    +L I
Sbjct: 1375 IIRKLQAQEIDEGSTANLVCKVTAAKPEP-SIKWTRDGVKIRENSRIKMVFDGETCSLTI 1433

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
             D   +D G+Y     N  GT   +CR+
Sbjct: 1434 RDATLDDEGVYKVTLTNEYGTASSTCRV 1461



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 5/102 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF- 1765
            +   P F   ++ + V E   A F+ R+     PK  VEW R    I  S R      + 
Sbjct: 1759 VPSKPEFKQKLRPLEVVEGSEAKFDVRIKSY--PKPEVEWYRGTTKITDSLRHQITEPYE 1816

Query: 1766 GYVALNMKYVNP--EDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            G    ++  +N   ED+  Y C A NE G+    + L V  K
Sbjct: 1817 GDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK 1858



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 5/95 (5%)

Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH--KN 4020
            DL  ++K+QPP F+    +QT +V+ E           G P+ +V W+ +G+ +L   K 
Sbjct: 1852 DLTVIEKQQPPTFLGDDGTQTIIVK-EGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQ 1910

Query: 4021 RFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
                  D  ++ + F     ED+G Y C A N  G
Sbjct: 1911 ETRKRGDESHLVV-FN-AKMEDAGSYKCEANNKLG 1943



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 11/163 (6%)

Query: 4087 IREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL 4146
            I+    S   T + +V +   R  P+F      V    GE  RF  +V G P P V +  
Sbjct: 2038 IQNQHGSTTTTVQVIVTQRSIR--PIFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHR 2095

Query: 4147 NGNTIVNGSRYKLTYD--GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV----- 4199
                I +G RY +  +  G++   I  TR  D G+ + I             L V     
Sbjct: 2096 ESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELT 2155

Query: 4200 IPRH-DDYRGVLKNAPRPWYDETTQYQRT-ETELEKTFEERQV 4240
            IP+   D  GV++      YD + + + T   E+E    ER +
Sbjct: 2156 IPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLI 2198



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 6/108 (5%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E I E +   P F   L  + E+ EG    F+ +L    +PT  VEWYK+ + I      
Sbjct: 2933 ELIIEPSVSPPSFRHRLTAV-EVDEGDETRFDVRLK--KEPTS-VEWYKEQQRIFTDGHF 2988

Query: 820  TSIFNFG--YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
              I        SL I + +  DAG Y   A+N+ G++ + A + V  R
Sbjct: 2989 EVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 46/165 (27%), Positives = 68/165 (41%), Gaps = 19/165 (11%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC--DFGF 3477
            P F   L+ +E + EG+   F+ RL    +P   VEWY   + +     F      +   
Sbjct: 2943 PSFRHRLTAVE-VDEGDETRFDVRLKK--EPT-SVEWYKEQQRIFTDGHFEVIEGEEECL 2998

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537
              L IS T   D+G Y C A N  G++ T A +       ++ E  +P G EG      +
Sbjct: 2999 YSLVISNTKVADAGGYKCTALNESGKSSTRAEL-------LVNERLIPPGFEG--PDHGS 3049

Query: 3538 LEGYSGTVDTLTPEA-ESGNP-PEFTTTPSDLILSENSSAHFECR 3580
             E   G  DT+T +A   GNP PE      + +  E+       R
Sbjct: 3050 YELQEG--DTITLDAVVKGNPYPEIRWYKDEFLAMESKKLMLSVR 3092



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 2/62 (3%)

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSD--FGFVTLDLVDVYERDSGIYTCKAYNKR 2992
            VE    P  K+EW    + L  G R  L  D       L + +    DSG YTC A NK 
Sbjct: 3548 VEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSGKYTCIARNKA 3607

Query: 2993 GE 2994
            GE
Sbjct: 3608 GE 3609



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            GG       + GNP P  +W R    L    +  +   +     SL I++I   DEGEY 
Sbjct: 5980 GGKITLTCLISGNPVPTATWFRGDEELKSGGRIHIETTDDRS--SLTIERIQFRDEGEYE 6037

Query: 146  CTARNQYGEAICSV 159
               +N  GE  C V
Sbjct: 6038 LVVKNDGGEDSCVV 6051



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 3/95 (3%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            KP+    +++     G  V  +  +     P  +VEW      ++ G RF    +   V 
Sbjct: 394  KPEIEDSLRDVSALPGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEVF 451

Query: 2037 LDILYAYAE-DTGTYMCKATNAVGEAVTTSSVKVD 2070
              I+    E D G Y C ATN  GEA + + + V+
Sbjct: 452  SLIIQDLEETDAGRYKCVATNEAGEAESMAQLTVN 486



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 3/85 (3%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SLDITHT 2838
            L ++    G+ + F+  +     P  K+EW      +  G R+    +   V SL I   
Sbjct: 401  LRDVSALPGERVKFKVRIGGKPKP--KVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDL 458

Query: 2839 YEEDSGIYTCKATNSKGSATTSGSL 2863
             E D+G Y C ATN  G A +   L
Sbjct: 459  EETDAGRYKCVATNEAGEAESMAQL 483



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            +VEG+ + L  +V  K  P+  IEW  +GK + + +            L + +    DSG
Sbjct: 503  VVEGESVELVARVTGKPAPE--IEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSG 560

Query: 2983 IYTCKAYNKRGEA 2995
            +Y C A NK G A
Sbjct: 561  LYRCTARNKSGTA 573



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 2/101 (1%)

Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
           EG +    A++T    P   +EW KDG+ +  ++ + +        L I     +D+G Y
Sbjct: 505 EGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLY 562

Query: 844 TVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKT 884
              A NK G A  T  + V  +        I  + R +E T
Sbjct: 563 RCTARNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEAT 603



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 50/207 (24%), Positives = 84/207 (40%), Gaps = 43/207 (20%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFGYVSMTISHVRDED 2445
            + EG       R+    +P   V+WF++ + I +S++  I +  +   +++ +S +  ED
Sbjct: 797  VTEGNEVSIQLRV--KANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSL--ED 852

Query: 2446 EGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREF 2505
             GVY C ASN LG+              ++++ + P+G                      
Sbjct: 853  TGVYKCEASNRLGK--------ASRSFDVKVQVKGPKG---------------------- 882

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS--RFRTTHDF 2563
            E PI    L  P E  EG+    + +    G P+   EW  +G+ ++     +  TT D 
Sbjct: 883  EAPIILSKLR-PVETEEGEET--KLKCTFTGKPAPTCEWTRDGIRIRSSRMVQIDTTEDS 939

Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590
               TL I     +D GLY C   N  G
Sbjct: 940  S--TLIIKETTLDDEGLYKCTIKNDLG 964



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            +AP     L  +ET EG    L+C     G      EW  +G  I++    +     D  
Sbjct: 883  EAPIILSKLRPVETEEGEETKLKCTF--TGKPAPTCEWTRDGIRIRSSRMVQIDTTEDSS 940

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             L +     +D G+Y C   N LG   TS  + V
Sbjct: 941  TLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLV 974



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 3/105 (2%)

Query: 631  DRVYPPPQFIVPLKS-VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
            + V   P+F+   +  +   EG  +    R+   G P  ++EW K  +++  SSR     
Sbjct: 1562 NEVLTVPEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFKS 1619

Query: 690  RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            R    ++ +  L + DSG Y C A +  G +     L V  +  I
Sbjct: 1620 RDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 3/90 (3%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR-PAYEFDY 1367
            QAP F+  +  +E  EG  V L   +      T  V+W  +G P+   +R    +     
Sbjct: 1961 QAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPT--VKWTRDGIPVFEDYRISMDSSRVQG 2018

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
            V L + +V   D GVY C   NQ G   T+
Sbjct: 2019 VTLIIRNVTRYDEGVYKCTIQNQHGSTTTT 2048



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 22/100 (22%), Positives = 39/100 (39%), Gaps = 2/100 (2%)

Query: 3550 PEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI 3609
            P+   G  P   +    + + E   A  E   +     +  +EW+ +G  +    RV++ 
Sbjct: 2249 PKRPEGTEPNIVSGLKSVEVKEGEQAELE--FVVSGTPTPTLEWYRDGLRVKESRRVRST 2306

Query: 3610 NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             + G   L I   +  D G Y C+  N  G  + S  L +
Sbjct: 2307 LENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSAHLNI 2346



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 6/105 (5%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            + P  + ++Q     +E E  K EC+++  G P   + W  +G   L  NR    +D   
Sbjct: 2549 EEPTILQRLQP-VDTIEGEAIKMECRVS--GKPEPTITWLKDGLVFLTDNRIKTYFDGDV 2605

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGIV 4072
              +    V   D G Y C A N  G   + A   V++   +P I+
Sbjct: 2606 CTLTIRDVKLGDEGIYRCNAKNSSGSAHSSAELTVLEREARPRIL 2650



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 13/118 (11%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGH-RYRTF 3334
            PS  PP F  ++  V ++ EG    F+ RL    +P   VEW+   +++   GH      
Sbjct: 2938 PSVSPPSFRHRLTAV-EVDEGDETRFDVRLKK--EPT-SVEWYKEQQRIFTDGHFEVIEG 2993

Query: 3335 HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392
             +  +  L I      ++G Y+C A N+ G+ ST+A L       L+ +  +P G EG
Sbjct: 2994 EEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL-------LVNERLIPPGFEG 3044



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 3/118 (2%)

Query: 3534 KIAALEGYSGTVDTLTPEAESGNP-PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVE 3592
            K  A+        + T   ES  P P F     D  + E  +   ECR +      M VE
Sbjct: 3406 KCVAMNPAGSASKSFTVVIESKKPAPLFIAPLHDQEVVEGETIRLECR-VRATPRPM-VE 3463

Query: 3593 WFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            W  +G+       + T  D     L I G    D G Y C A N+ G      +L VK
Sbjct: 3464 WKKDGRTFKEDYHIYTEFDGQHCTLVIKGAQIEDEGAYECIAKNKEGRGRSVAQLTVK 3521



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 11/127 (8%)

Query: 3391 EGGLEKLQTLEDSMVRRKDTSVE-EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDD 3449
            + G  K+    DS        ++ +E+   P     L ++  L  GE   F+ R+     
Sbjct: 365  DAGTYKVVARNDSGTAHSIAELQVQERSTKPEIEDSLRDVSAL-PGERVKFKVRIGGKPK 423

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCD----FGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505
            P  KVEW      ++ G RF    +    F  +I ++  T   D+G Y C A N  GEA 
Sbjct: 424  P--KVEWRKGKSVIEDGERFTIAEESDEVFSLIIQDLEET---DAGRYKCVATNEAGEAE 478

Query: 3506 TTASMKV 3512
            + A + V
Sbjct: 479  SMAQLTV 485



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 31/124 (25%), Positives = 48/124 (38%), Gaps = 6/124 (4%)

Query: 3976 VTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNF 4035
            +T+      + E E    EC ++  G P+  VEW  +   L    R     D     + F
Sbjct: 1096 ITKPLESVEVNEGEDFDLECVVS--GSPSPTVEWTKDLVKLRTSYRLKEKLDGNVAKLVF 1153

Query: 4036 GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQ 4095
                PED GEY C   N +G   T   +K      ++   +    M  +E     EA+++
Sbjct: 1154 KQARPEDIGEYKCTVINEHGKASTTGEVKV----NVLSRPEFKIKMSPVEVTEGSEAAFE 1209

Query: 4096 VTPE 4099
            V  E
Sbjct: 1210 VRVE 1213



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P F  ++ S   + E     FE ++   G P ++VEWF     +    R+T   D     
Sbjct: 1189 PEFKIKM-SPVEVTEGSEAAFEVRVE--GFPKLQVEWFKGMTKIEDSGRYTFTADKNRYT 1245

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
            M    V  ED+G Y C ATN  G   ++A
Sbjct: 1246 MVIANVTLEDAGGYRCVATNTAGKTTSRA 1274



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 27/102 (26%), Positives = 40/102 (39%), Gaps = 5/102 (4%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF- 2032
            V  KP+F + ++  EV EG     +  +     P   VEWY     +    R + T  + 
Sbjct: 1759 VPSKPEFKQKLRPLEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITEPYE 1816

Query: 2033 --GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
                 +L IL    ED   Y C A N  G+    + + V  K
Sbjct: 1817 GDDTYSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTVIEK 1858



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 3/99 (3%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD-FGY 2034
            + P F   +   EV EG  V L   ++    PT  V+W  +G PV + +R          
Sbjct: 1961 QAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPT--VKWTRDGIPVFEDYRISMDSSRVQG 2018

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
            V L I      D G Y C   N  G   TT  V V  +S
Sbjct: 2019 VTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS 2057



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 3/96 (3%)

Query: 1978 PQFGKPIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            PQF   +    E+ +G   + + +L     P   +EWY N R +    R + ++      
Sbjct: 2157 PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            + +     +D+G Y CKA N  G      ++ V  K
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK 2250



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            R ++ + + +  P   T E +  I VPEGG      +V    +P  ++ W+ +G+  +  
Sbjct: 2438 RADLEVNERQFAPEFETGEERGPIVVPEGGETTL--KVTLRANPKPQVIWYKDGKHTSEN 2495

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779
             R+   +      L I      D+G Y C A NK G A
Sbjct: 2496 IRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLGFA 2533



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +   EGG+   +  +    +P  ++ W K+G+    + R     R     L + +  I+D
Sbjct: 2461 IVVPEGGETTLKVTLR--ANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIED 2518

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751
            SG Y C A +  G A+    + V      + T + P  LQ +Q ++
Sbjct: 2519 SGSYKCEARNKLGFADKSFTIRV---EVPKPTGEEPTILQRLQPVD 2561



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 14/139 (10%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            +V  + +P  ++ WY +GK   +  R  + S      L + +    DSG Y C+A NK G
Sbjct: 2472 KVTLRANPKPQVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIEDSGSYKCEARNKLG 2531

Query: 2994 EAFTSSTVYCTSKDNLIERTQHPKGT-EGLEKIQNLE--DSLRKEPGQQPDDDTGRPPEF 3050
             A  S T+          R + PK T E    +Q L+  D++  E  +     +G+P   
Sbjct: 2532 FADKSFTI----------RVEVPKPTGEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPT 2581

Query: 3051 TTVFKD-IVDISEGQIAHY 3068
             T  KD +V +++ +I  Y
Sbjct: 2582 ITWLKDGLVFLTDNRIKTY 2600



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 14/124 (11%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E+ IE    +PP F   +   ++V EG    FD R++   +PT  ++W+   +   T   
Sbjct: 2933 ELIIEPSV-SPPSFRHRLTA-VEVDEGDETRFDVRLKK--EPTS-VEWYKEQQRIFTDGH 2987

Query: 3744 VHTLN--DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801
               +   +    +L I      DAG Y C A N+ G ++T A++       +V E  +P 
Sbjct: 2988 FEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAEL-------LVNERLIPP 3040

Query: 3802 GMSG 3805
            G  G
Sbjct: 3041 GFEG 3044



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 4/101 (3%)

Query: 1987 AEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAED 2046
            A + EG  + L  ++T   +P   ++WY +G  +++      +      +L I+    ED
Sbjct: 3344 ALLNEGDDLRLVVSVT--GNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPED 3401

Query: 2047 TGTYMCKATNAVGEAVTTSSVKVDAK--SGLYLDTLDEQRL 2085
            TG   C A N  G A  + +V +++K  + L++  L +Q +
Sbjct: 3402 TGVIKCVAMNPAGSASKSFTVVIESKKPAPLFIAPLHDQEV 3442



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 4122 VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD---GMYHFDIPKTRQYDTG 4178
            V EG+ A+F   V+G P  +V WL     + NG R  L  D    MY   I   +  D+G
Sbjct: 3538 VIEGDRAKFHVEVSGKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSG 3597

Query: 4179 KIEVI 4183
            K   I
Sbjct: 3598 KYTCI 3602



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 2/101 (1%)

Query: 62   TAGRPGEP-SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            T G P E  +PP F  + +N    +GG  KF  ++       V W  K   L+  +    
Sbjct: 3865 TEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVISKAPIKVEW-YKDDRLISSDWPRH 3923

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
             +       ++ I  +   D G YT    N+YG      Y+
Sbjct: 3924 TFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESKAYL 3964



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 3/146 (2%)

Query: 1019 KIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTV 1077
            K+    D  + + R +  VK  Q  P F+   +G      G        V  +   ++T 
Sbjct: 176  KVVATNDVGKVTSRADLRVKERQFAPEFIDEERGPIDATTGDEVTLTCSVSGKPKPSIT- 234

Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             WY NGK +T + ++          + + S + ED+ +Y   A N  G+A  +  + V+ 
Sbjct: 235  -WYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFDVKVKA 293

Query: 1138 RSSIDTSSIHRGLYEKTRHIEESKFV 1163
                  S      + +    EESK V
Sbjct: 294  PKGDAPSFTIDLTHVRAIEGEESKLV 319



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 17/56 (30%), Positives = 28/56 (50%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W++N KL+ DS ++          +T+   + ED  +Y C A N LG+
Sbjct: 227  GKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGK 282



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +API  + L+  +   EG+   L+     +  P    EW ++G+ + +   ++       
Sbjct: 883  EAPIILSKLRPVET-EEGEETKLKCTFTGKPAPTC--EWTRDGIRIRSSRMVQIDTTEDS 939

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             TL I     DD G+Y C   N LG   ++A + + +
Sbjct: 940  STLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNE 976



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 7/144 (4%)

Query: 2863 LRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGR-----RPSVPDTEYPKPEWIIPI 2917
            +R  GD +  F  +     AG+   +    A  A        + S P T   +P  I  +
Sbjct: 1320 VRAIGDSHTCFIVRAKLSDAGVYKCQATNAAGSASRSWEVKVKQSAPKTTGEEPIIIRKL 1379

Query: 2918 AAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVY 2977
             A+ ++ EG   +L  +V     P+  I+W  +G  + + SR K+  D    +L + D  
Sbjct: 1380 QAQ-EIDEGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDAT 1437

Query: 2978 ERDSGIYTCKAYNKRGEAFTSSTV 3001
              D G+Y     N+ G A ++  V
Sbjct: 1438 LDDEGVYKVTLTNEYGTASSTCRV 1461



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 2/95 (2%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            GN P+  T      + E  +   EC +      +  +EW+ +G       RV T  D   
Sbjct: 1665 GNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFDGSV 1722

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              +        D G Y C ATN  G A  S +L V
Sbjct: 1723 ASVTFTDAQGFDDGEYKCVATNPLGSAQSSARLTV 1757



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 3/97 (3%)

Query: 2639 QQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            QQ P F     +   +V EG  + + A +  +  P  ++ W+K+G  +    + ++    
Sbjct: 1859 QQPPTFLGDDGTQTIIVKEGDDLNISATIAGKPSP--EVSWYKDGRLVLDSIKQETRKRG 1916

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                L + + + +D+G Y C+A N LG    T ++K+
Sbjct: 1917 DESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKV 1953



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 4/72 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-MTISHVRDEDE 2446
            ++EG   +    +   G P+ +V W+++ +L+ DS +  +T   G  S + + + + ED 
Sbjct: 1875 VKEGDDLNISATI--AGKPSPEVSWYKDGRLVLDSIK-QETRKRGDESHLVVFNAKMEDA 1931

Query: 2447 GVYMCRASNLLG 2458
            G Y C A+N LG
Sbjct: 1932 GSYKCEANNKLG 1943



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK-STFDFG 2698
            QAP FT+ +   + + EG  V L   +     P +K  W ++G+ +    R+   +    
Sbjct: 1961 QAPSFTSEMSQVE-VDEGGEVKLYFLISGYPKPTVK--WTRDGIPVFEDYRISMDSSRVQ 2017

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             VTL I ++   D G+Y C   N  G   +T  + +  R
Sbjct: 2018 GVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQR 2056



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 36/117 (30%), Positives = 51/117 (43%), Gaps = 9/117 (7%)

Query: 1030 SKRTEEEVKITQKPRFLGPLKGTN-KIVEG---QSAHFEARVEPQSDLTMTVEWYFNGKQ 1085
            S  T  +V +TQ  R + P+ G   K VEG   +   FE +VE        V ++   +Q
Sbjct: 2044 STTTTVQVIVTQ--RSIRPIFGQKMKNVEGRIGEDVRFEIQVEGTP--VPAVTFHRESEQ 2099

Query: 1086 ITSANRIQTYHDF-GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
            I    R     +  G   L I + R ED+G Y  +A N AGE      + VE   +I
Sbjct: 2100 IYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTI 2156



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 6/102 (5%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            +  S   P F+  +   + + EG    F+ RL+    S   VEW K+ + +         
Sbjct: 2936 IEPSVSPPSFRHRLT-AVEVDEGDETRFDVRLKKEPTS---VEWYKEQQRIFTDGHFEVI 2991

Query: 962  FNFG--YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                    +L I +  V DAG Y C A N  G+++T A L +
Sbjct: 2992 EGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLV 3033



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 6/102 (5%)

Query: 2224 EAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGK 2283
            EA  H++ + + +P + P  F   L+    V EG  A F  +V+   +P  ++E++  GK
Sbjct: 3220 EASSHASLV-LSKPLVMP-EFKERLKNIK-VVEGDEAQFSVRVKG--EPEPKVEWFKTGK 3274

Query: 2284 ALQSAARFHITFDFGYV-SLDIQHCVPEDAGEYSVKAINALG 2324
             ++S ARF       +  +L I     ED G Y   A N  G
Sbjct: 3275 KIKSHARFSSKAGEKHTYTLTISDVAMEDFGTYKCVASNDAG 3316



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L ++   EG+     C V     PT  IEW     P+ +  R ++  + +  +L I
Sbjct: 301  FTIDLTHVRAIEGEESKLVCKVTGKPAPT--IEWLKGELPVTTSLRVRTDFEKNVATLVI 358

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLR 2864
              T   D+G Y   A N  G+A +   L+
Sbjct: 359  KDTRLGDAGTYKVVARNDSGTAHSIAELQ 387



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)

Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF--- 825
           RP+F   L+ +  + EG     + ++     P   +EWY+    I  S R   +      
Sbjct: 685 RPEFRTKLKPVKAV-EGEEVQLDVKVEGYPKPD--IEWYRGTTMIVESGRFKVMEEEEED 741

Query: 826 GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           G  SL I  L+ +D G+  V A N  G+A S A + V  R
Sbjct: 742 GLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEVKER 781



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 18/58 (31%), Positives = 27/58 (46%)

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            EW +DG  + +S  +          L IK  T+ D G Y C   N +G  +TSA + +
Sbjct: 917  EWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLV 974



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            ++ EG   +  C+V     P   I W  +G      SR+  + D    +L I      D 
Sbjct: 1383 EIDEGSTANLVCKVT-AAKPEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDE 1441

Query: 3766 GEYTCRATNKWGSATTTAKI 3785
            G Y    TN++G+A++T ++
Sbjct: 1442 GVYKVTLTNEYGTASSTCRV 1461



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/99 (24%), Positives = 43/99 (43%), Gaps = 2/99 (2%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P+F+   +   E  EG +     ++     P   +EW+K  R +  SSRI         +
Sbjct: 1568 PEFMDKAEGPIEKTEGDDLELTVRVR--GKPQPELEWFKYDRTLWKSSRINFKSRDNKFT 1625

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
            + +  L  +D+G Y   A NK G +  T ++ V  +  +
Sbjct: 1626 MTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVI 1664



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 3/119 (2%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P+F+  +     LV+ +   ++  L   G P  ++EW+ N + +   +R    +      
Sbjct: 2157 PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREME 4091
            +    V  +DSG Y C+A N  G    +  I    K     +  +   +KS+E ++E E
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPKRPEGTEPNIVSGLKSVE-VKEGE 2272



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 2/96 (2%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+FI  +  V +LV+G +  ++  L     P  ++EW++N + +    R +         
Sbjct: 2157 PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 2214

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
            + +     ++SG Y C A N  G  S + N+    K
Sbjct: 2215 IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQPK 2250



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 15/50 (30%), Positives = 27/50 (54%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            ++EWYHN + + + SR   +       + + +   +DSG Y C+A+N  G
Sbjct: 2188 EIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 2237



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 22/105 (20%), Positives = 49/105 (46%), Gaps = 2/105 (1%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDT 2047
            E+ EG  + L+A +    +P   + WY +     +  +   +      +L + +   +D+
Sbjct: 3051 ELQEGDTITLDAVVK--GNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDS 3108

Query: 2048 GTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092
            G Y C   N VG A  + +V V+AK    +     ++L++++ ++
Sbjct: 3109 GVYKCVLKNKVGTATKSFTVDVEAKKSKGIIPEFFRQLRRVEAVQ 3153



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 1/64 (1%)

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DT 1427
            +L L  V P+DSGVY C   N++G A  S  + V AKK   +  +    L +++ ++  T
Sbjct: 3097 SLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKKSKGIIPEFFRQLRRVEAVQGST 3156

Query: 1428 SRYK 1431
            +R++
Sbjct: 3157 ARFE 3160



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 28/110 (25%), Positives = 51/110 (46%), Gaps = 4/110 (3%)

Query: 2229 STRIEVEEPKISPPRFVTE-LRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287
            S R++V+E ++ PP   T+ L G   + EG        V     P+L  ++Y +G  ++ 
Sbjct: 3321 SGRLDVKE-RMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDL--QWYKDGVLIRR 3377

Query: 2288 AARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
            +    ++      SL I   VPED G     A+N  G  + + ++ + +K
Sbjct: 3378 STHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESK 3427



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 2643 IFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTL 2702
            I T  L+    L EG  + L   V     P+L  +W+K+GV +     +  +      +L
Sbjct: 3335 ISTDVLEGPALLNEGDDLRLVVSVTGNPIPDL--QWYKDGVLIRRSTHISLSSIGSRYSL 3392

Query: 2703 SINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            +I  +  +D+G+  C A N  G A  + ++ IE +
Sbjct: 3393 AIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESK 3427



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 14/94 (14%)

Query: 934  EPIGDSTLRVEWLKDG----RPVEASSRITTFFNFGYVA--------LTIKSVTVHDAGH 981
            +P+  S  R    ++G    RP E  SR    F F YV         L I   T+ D G 
Sbjct: 5884 DPLASSVSRGRRTRNGNRMARPPETRSRKDLLFRF-YVRKSPERCCHLCISCATIEDEGE 5942

Query: 982  YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPG 1015
            YTCRA N  G  + +A L IV     + ++  PG
Sbjct: 5943 YTCRASNPAGSCSCTAEL-IVDAPAKVDQAATPG 5975



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 6/124 (4%)

Query: 2235 EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT 2294
            + PK   P+ +  L G   V E + A   C +     PN   E+Y +   ++ + R    
Sbjct: 2    KRPKGDRPQILQPLEGVD-VKEDENAILSCTISGTPTPNA--EWYRDSIRVRESRRIKSE 58

Query: 2295 FDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTS--AISMTVTAKGSIISESQRPEGLEK 2352
               G  +L I+    ED GEY     N  G  TS   +++ V  K S  S+  +P   E+
Sbjct: 59   VVNGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVRVPVKPSFTSK-MKPVDAEE 117

Query: 2353 IREL 2356
             +E+
Sbjct: 118  GQEV 121



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSLD 2834
            F S +  +  +EG  + F+ +V+ S  P   + W+  +  + +  R++       +V+L 
Sbjct: 106  FTSKMKPVDAEEGQEVRFDVHVKGSPKPD--VVWYKGSTMIGTHERFQIVEAAEDHVTLV 163

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            I+    ED+  Y   ATN  G  T+   LR
Sbjct: 164  ISEVKLEDAETYKVVATNDVGKVTSRADLR 193



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            PE+I           G  + L   V  K  P   I WY NGK+L    +  + S      
Sbjct: 201  PEFIDEERGPIDATTGDEVTLTCSVSGKPKPS--ITWYKNGKLLTDSLKLDIRSSGERNW 258

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEA 2995
            + ++     D+ +Y C+A NK G+A
Sbjct: 259  VTMLSAKPEDTALYKCEAENKLGKA 283



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 19/57 (33%), Positives = 27/57 (47%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
            G PK  + W +NG  +  S +L          + M    PED+  Y C A N+LG+A
Sbjct: 227  GKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKA 283



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 24/74 (32%), Positives = 40/74 (54%), Gaps = 8/74 (10%)

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG---YVALDIIDLIAE 1512
            V EG  V  + +++   + N  V+WFK+G+P+    + R I   G    +A+ +  L  E
Sbjct: 797  VTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTK-RDIKRRGEEHTLAIHVSSL--E 851

Query: 1513 DSGIYTCRAVNLVG 1526
            D+G+Y C A N +G
Sbjct: 852  DTGVYKCEASNRLG 865



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 2/102 (1%)

Query: 3411 SVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            S  +  G+ P+    L   + + EG  A+   ++T    P   ++W  +G  ++  SR +
Sbjct: 1364 SAPKTTGEEPIIIRKLQ-AQEIDEGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIK 1421

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
               D     L I     +D G Y     N YG A +T  + V
Sbjct: 1422 MVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASSTCRVLV 1463



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 5/119 (4%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG   +  C V  ++ P   I+W  +   +   +R K   D    SL I     +D G+Y
Sbjct: 1386 EGSTANLVCKVTAAK-PEPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVY 1444

Query: 2847 TCKATNSKGSATTSGSLRC--TGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV 2903
                TN  G+A+++  +     G + I+   Q  +  + +E      E +L+   RP+V
Sbjct: 1445 KVTLTNEYGTASSTCRVLVNEVGSRPIF--QQKLKAVSTIEGESTRFEVKLSAMPRPTV 1501



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 25/97 (25%), Positives = 38/97 (39%), Gaps = 1/97 (1%)

Query: 3966 DVDKKQPPRFVTQIQSQTSLVEM-ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTP 4024
            +V  K+P      I S    VE+ E  + E +    G P   +EW+ +G  +    R   
Sbjct: 2246 NVQPKRPEGTEPNIVSGLKSVEVKEGEQAELEFVVSGTPTPTLEWYRDGLRVKESRRVRS 2305

Query: 4025 IYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
              + G   +     + ED G Y C+  N  G   T A
Sbjct: 2306 TLENGIARLVITETWAEDMGTYKCQVRNDLGRTSTSA 2342



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 2/104 (1%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    P F+ P      ++EG     +A ++  G+    + W KD      S ++   
Sbjct: 3033 VNERLIPPGFEGPDHGSYELQEGDTITLDAVVK--GNPYPEIRWYKDEFLAMESKKLMLS 3090

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
                  +LT+  V   D+G Y C   N +G AT S  + +  KK
Sbjct: 3091 VRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEAKK 3134



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 5/96 (5%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA-LDIMSC 1642
            L+ VE  +G  A FE ++    +   ++ W  + K L    R+ +    G V  L     
Sbjct: 3146 LRRVEAVQGSTARFECKVSGHPEP--QIAWLKDGKELAI-PRYIKPFYDGEVCKLTFYET 3202

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE 1678
             PED G YTC A N  GEA +S  ++V SK  +  E
Sbjct: 3203 QPEDEGDYTCVASNEAGEA-SSHASLVLSKPLVMPE 3237



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 23/96 (23%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P  + P+ +  ++ V  + E ++A     +     P+   EW+ +  ++    R ++   
Sbjct: 4    PKGDRPQILQPLEGVD-VKEDENAILSCTISGTPTPN--AEWYRDSIRVRESRRIKSEVV 60

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             G+  L I     E+ GEY+CV  N+ G  ++KA L
Sbjct: 61   NGMATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPL 96



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 2/98 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            + P F   + +    EG    L   +T    PT  +EW     PV    R +T ++    
Sbjct: 297  DAPSFTIDLTHVRAIEGEESKLVCKVTGKPAPT--IEWLKGELPVTTSLRVRTDFEKNVA 354

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
             L I      D GTY   A N  G A + + ++V  +S
Sbjct: 355  TLVIKDTRLGDAGTYKVVARNDSGTAHSIAELQVQERS 392



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            I PRF    +S   V+EG+ V    ++        ++EW K+G+ V   +          
Sbjct: 490  IGPRFEKMKESF-TVVEGESVELVARVTGKPAP--EIEWTKDGKTVRKTNNVDTKERDDQ 546

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
              L I +   +DSG+Y C A N  GT +++ +L
Sbjct: 547  AVLTIEESSRDDSGLYRCTARNKSGTADMTFQL 579



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 4/72 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTISHVRDEDE 2446
            + EG++     R+   G P  ++EW ++ K +  ++ + TK  D   V +TI     +D 
Sbjct: 503  VVEGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAV-LTIEESSRDDS 559

Query: 2447 GVYMCRASNLLG 2458
            G+Y C A N  G
Sbjct: 560  GLYRCTARNKSG 571



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 8/111 (7%)

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEG-----QVEPKNDPDLKIEWYFN 2950
            A G+  S  D E  + E+      +    EG ++  EG     Q+  K +P+  ++W+ +
Sbjct: 766  ASGKATSRADLEVKEREFAPEFEGDE---EGPIVVTEGNEVSIQLRVKANPNADVDWFKD 822

Query: 2951 GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            G+ + + ++  +       TL +      D+G+Y C+A N+ G+A  S  V
Sbjct: 823  GRPIYESTKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDV 873



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 3/109 (2%)

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            R D  V+E +  AP F         + EG     + R+    +PN  V+W+ +G+ +   
Sbjct: 773  RADLEVKEREF-APEFEGDEEGPIVVTEGNEVSIQLRVKA--NPNADVDWFKDGRPIYES 829

Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            ++           L I  +  ED+G Y C A N  G+A  +  +KVQ K
Sbjct: 830  TKRDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQVK 878



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 2/94 (2%)

Query: 2497 RSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSR 2556
            +   P    E+PI  + L    E+ EG  A+   +V     P    +W  +GV+++  SR
Sbjct: 1362 KQSAPKTTGEEPIIIRKLQA-QEIDEGSTANLVCKVT-AAKPEPSIKWTRDGVKIRENSR 1419

Query: 2557 FRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             +   D    +L I     +D G+Y     N  G
Sbjct: 1420 IKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYG 1453



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 2/77 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EGD++     V     P L  EWF  ++ L   +R       +  ++ ++    +DSG+Y
Sbjct: 1582 EGDDLELTVRVRGKPQPEL--EWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMY 1639

Query: 2847 TCKATNSKGSATTSGSL 2863
             C A N  GS++ + +L
Sbjct: 1640 QCVARNKAGSSSRTFNL 1656



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 3/98 (3%)

Query: 3280 EPPKFITQIQDVTKLV-EGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            +PP F+      T +V EG   +  A +     P+  V W+ +G+ +    +  T     
Sbjct: 1860 QPPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPE--VSWYKDGRLVLDSIKQETRKRGD 1917

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTS 3376
               L +     E++G Y+C A NKLG  +   N+K  S
Sbjct: 1918 ESHLVVFNAKMEDAGSYKCEANNKLGTVTKTYNVKVMS 1955



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 21/83 (25%), Positives = 32/83 (38%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP F+    + T+   EG            P   + WY++G+L+    +  T        
Sbjct: 1861 PPTFLGDDGTQTIIVKEGDDLNISATIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESH 1920

Query: 3889 LDILYVYAEDSGEYICRAVNDFG 3911
            L +     ED+G Y C A N  G
Sbjct: 1921 LVVFNAKMEDAGSYKCEANNKLG 1943



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 17/82 (20%), Positives = 42/82 (51%), Gaps = 2/82 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            I+ KEGD+++    +  +  P+ ++ W+ + + +    + ++        L + +   ED
Sbjct: 1873 IIVKEGDDLNISATI--AGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMED 1930

Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864
            +G Y C+A N  G+ T + +++
Sbjct: 1931 AGSYKCEANNKLGTVTKTYNVK 1952



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYIS 695
            P+ +  L+ V +  G +  F+ R+   G P   ++W +  + I     +       GY S
Sbjct: 2647 PRILEKLQDVDSSVGERAMFKIRVS--GSPMPVVQWYRRDEEITTKGHYIVRDEGRGYFS 2704

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            L +  ++ +D G Y    ++ +G   + AVL +
Sbjct: 2705 LTIEYIDYEDEGAYKAVVINDSGEVSSTAVLRL 2737



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 3/123 (2%)

Query: 1019 KIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTV 1077
            K   L ++ + S R E  V      P F GP  G+ ++ EG +   +A V+   +    +
Sbjct: 3015 KCTALNESGKSSTRAELLVNERLIPPGFEGPDHGSYELQEGDTITLDAVVK--GNPYPEI 3072

Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVET 1137
             WY +      + ++         +L +  V  +DSGVY  V +N  G A  S ++ VE 
Sbjct: 3073 RWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSGVYKCVLKNKVGTATKSFTVDVEA 3132

Query: 1138 RSS 1140
            + S
Sbjct: 3133 KKS 3135



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 35/126 (27%), Positives = 51/126 (40%), Gaps = 9/126 (7%)

Query: 2905 DTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRF 2960
            D E  K + IIP         + V+G     E +V     P+ +I W  +GK L      
Sbjct: 3129 DVEAKKSKGIIPEFFRQLRRVEAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYI 3186

Query: 2961 KLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTS---KDNLIERTQHPK 3017
            K   D     L   +    D G YTC A N+ GEA + +++  +         ER ++ K
Sbjct: 3187 KPFYDGEVCKLTFYETQPEDEGDYTCVASNEAGEASSHASLVLSKPLVMPEFKERLKNIK 3246

Query: 3018 GTEGLE 3023
              EG E
Sbjct: 3247 VVEGDE 3252



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 4/97 (4%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY-DFGFV 1235
            P F + L N   V EG       R++  G+P  +VEWF  G+ +   +RF +   +    
Sbjct: 3236 PEFKERLKNIKVV-EGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
             L I      D G Y   A N  G    S  + V ER
Sbjct: 3293 TLTISDVAMEDFGTYKCVASNDAGKVQCSGRLDVKER 3329



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/104 (25%), Positives = 42/104 (40%), Gaps = 1/104 (0%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    PE  T + +  ++   G       +   G+    ++W KDG  +  S+ I+  
Sbjct: 3326 VKERMVPPEISTDVLEGPALLNEG-DDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLS 3384

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
                  +L I  V   D G   C A N  G A+ S  + I +KK
Sbjct: 3385 SIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKK 3428



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 48/246 (19%), Positives = 92/246 (37%), Gaps = 12/246 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFT-PIYDFGYV 4031
            P F+ ++Q    +VE    +   ++  V +P  +++W+ + + +    R      + G  
Sbjct: 3735 PSFLQRMQD-LEIVEGSAARLCVRVQGVPEP--EIDWYKDNRVIREGGRVEFEFEEDGLC 3791

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKA--VIKTTGKPGIVYDSQLPKHMKSIEKIRE 4089
             +        D G Y C  +N  G  +  A   I+T G    V D+ L    +   +   
Sbjct: 3792 MLVIRDATKSDRGRYKCVVSNAAGKAQCSAELFIETHGFDSGVSDADLDFAARKEAREST 3851

Query: 4090 MEASWQVTPEQVVEESKAR---CPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL 4146
            +E     T ++   E   +    PP F  +     V+EG   +F  RV      +V W  
Sbjct: 3852 IELISDDTSDEEKTEGAPKEEGAPPEFTLVLRNREVKEGGVTKFASRVISKAPIKVEWYK 3911

Query: 4147 NGNTIVNG-SRYKLTYD-GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHD 4204
            +   I +   R+   +D  +Y  +I   +  D G    +             L V+P  +
Sbjct: 3912 DDRLISSDWPRHTFEHDEDLYAMNISNVKVADGGPYTFVVSNKYGTVESKAYLNVLPEME 3971

Query: 4205 -DYRGV 4209
             ++ G+
Sbjct: 3972 PEFEGI 3977



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 18/45 (40%), Positives = 25/45 (55%)

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
            D GEYTCRA+N  GS + TA++   A   +   +    G+ G KI
Sbjct: 5939 DEGEYTCRASNPAGSCSCTAELIVDAPAKVDQAATPGSGVVGGKI 5983



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/96 (23%), Positives = 37/96 (38%), Gaps = 2/96 (2%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G+ P+       + + E+ +A   C +      +   EW+ +   +    R+K+    G 
Sbjct: 6    GDRPQILQPLEGVDVKEDENAILSCTIS--GTPTPNAEWYRDSIRVRESRRIKSEVVNGM 63

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
              L I      D G Y C   N HG AT    L V+
Sbjct: 64   ATLTIKQTRAEDQGEYKCVLRNEHGTATSKAPLNVR 99



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 54/222 (24%), Positives = 90/222 (40%), Gaps = 38/222 (17%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            V +KP F ++ K ++   EGQ V F+  ++     +  V W+K    +    RF+ +   
Sbjct: 100  VPVKPSFTSKMKPVD-AEEGQEVRFDVHVKGSPKPD--VVWYKGSTMIGTHERFQIVE-- 154

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559
               A D + L+  +  +       +V T++V  ++T R+    +R  + +   E I   E
Sbjct: 155  --AAEDHVTLVISEVKLEDAETYKVVATNDVG-KVTSRAD---LRVKERQFAPEFID--E 206

Query: 1560 DRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKP 1619
            +R     T   DEVT     C+ S K                 P    T    WY N K 
Sbjct: 207  ERGPIDATTG-DEVTLT---CSVSGK-----------------PKPSIT----WYKNGKL 241

Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            L    +    ++     + ++S  PED+  Y C A N LG+A
Sbjct: 242  LTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKA 283



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 3/101 (2%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            V+  KG+AP+    L  +E   EGE    + + T T  P    EW  +G  +++    + 
Sbjct: 877  VKGPKGEAPIILSKLRPVET-EEGEET--KLKCTFTGKPAPTCEWTRDGIRIRSSRMVQI 933

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
                    L I  T  +D G Y C   N+ G   T+A + V
Sbjct: 934  DTTEDSSTLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLV 974



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/102 (25%), Positives = 42/102 (41%), Gaps = 3/102 (2%)

Query: 3552 AESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIND 3611
            A  G  P FT+  S + + E      +   +        V+W  +G P+    R+   + 
Sbjct: 1957 APEGQAPSFTSEMSQVEVDEGGEV--KLYFLISGYPKPTVKWTRDGIPVFEDYRISMDSS 2014

Query: 3612 -FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
                V L I  V + D G+Y C   N+HG  T + ++ V  R
Sbjct: 2015 RVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQR 2056



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV-A 1369
            P F + + N+E   G +V  E +++  G     V +    + I  G R+    E + +  
Sbjct: 2060 PIFGQKMKNVEGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFV 2117

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L + +  PED+G Y C A N  GE  +   L V
Sbjct: 2118 LTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHV 2150



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 7/115 (6%)

Query: 1310 APQFSRALHN--IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367
            AP+F        I   EG    L+  L+   +   +V W+ +GK      R       + 
Sbjct: 2449 APEFETGEERGPIVVPEGGETTLKVTLR--ANPKPQVIWYKDGKHTSENIRLDVRSRGNT 2506

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQ 1422
              L + +   EDSG Y C+A N+LG A  S  +RV   K      + P+ L+++Q
Sbjct: 2507 HYLKITNAKIEDSGSYKCEARNKLGFADKSFTIRVEVPKP---TGEEPTILQRLQ 2558



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 36/147 (24%), Positives = 58/147 (39%), Gaps = 4/147 (2%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P    P+ + +++   ++ EG S     R+     P   +EW+ +   L    R    H 
Sbjct: 2842 PGEAAPEIVQRLK-ACEVPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHT 2898

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK 3396
                 L+ L     + G Y  VA N LG  ST A L      +          +E   E 
Sbjct: 2899 GDQYFLNFLETEARDEGRYMLVAKNHLGSVSTSAELIIEPSVSPPSFRHRLTAVEVD-EG 2957

Query: 3397 LQTLEDSMVRRKDTSVEEEKGKAPVFT 3423
             +T  D  ++++ TSVE  K +  +FT
Sbjct: 2958 DETRFDVRLKKEPTSVEWYKEQQRIFT 2984



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 20/62 (32%), Positives = 31/62 (50%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            ++WY +G  I  +  I         +L I  V  ED+GV   VA N AG A  S ++ +E
Sbjct: 3366 LQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIE 3425

Query: 1137 TR 1138
            ++
Sbjct: 3426 SK 3427



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 8/135 (5%)

Query: 1007 IIAESQHPGGLEKIQYLEDASRYSKRTEEEVKIT------QKPRFLGPLKGTNKIVEGQS 1060
            I+       G+ K Q    A   S+  E +VK +      ++P  +  L+   +I EG +
Sbjct: 1331 IVRAKLSDAGVYKCQATNAAGSASRSWEVKVKQSAPKTTGEEPIIIRKLQA-QEIDEGST 1389

Query: 1061 AHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVA 1120
            A+   +V        +++W  +G +I   +RI+   D    +L I     +D GVY V  
Sbjct: 1390 ANLVCKVTAAKP-EPSIKWTRDGVKIRENSRIKMVFDGETCSLTIRDATLDDEGVYKVTL 1448

Query: 1121 RNAAGEAQLSASMTV 1135
             N  G A  +  + V
Sbjct: 1449 TNEYGTASSTCRVLV 1463



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 4/120 (3%)

Query: 2924 VEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSD--FGFVTLDLVDVYERDS 2981
            +EG+    E ++     P   +EW+ +   +  G RF +T +   G   L + D    D+
Sbjct: 1482 IEGESTRFEVKLSAMPRPT--VEWFKSSSQIYDGGRFTITEEENSGVYVLVIEDTNIEDA 1539

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD 3041
            G Y   AYN  G+  + + +       + E     +G     +  +LE ++R     QP+
Sbjct: 1540 GTYKVVAYNNLGKVTSQALLRVNEVLTVPEFMDKAEGPIEKTEGDDLELTVRVRGKPQPE 1599



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 9/131 (6%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V T P+F+ + +   +E++EG   E  V  +  P+  +EW++  + L    R        
Sbjct: 1564 VLTVPEFMDKAEG-PIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKSRDN 1622

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK------LPDIILQNQVPRGMKR 3939
              ++ +  +  +DSG Y C A N  G       +  +K       PDII  + + + +K 
Sbjct: 1623 KFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKKKVIGNAPDII-THLISKEVKE 1681

Query: 3940 SEALTQMEATI 3950
               +T +E T+
Sbjct: 1682 GGTVT-LECTV 1691



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 5/91 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS---YVS 2832
            F   L  +   EG    F+  ++    P  ++EW+     +    R++ T  +      S
Sbjct: 1765 FKQKLRPLEVVEGSEAKFDVRIKSYPKP--EVEWYRGTTKITDSLRHQITEPYEGDDTYS 1822

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I +T  ED+ +Y C A N  G  T    L
Sbjct: 1823 LIILNTTMEDAAMYKCVAFNEAGKTTCRADL 1853



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH--DFGY 2166
            P F   LT++E + EGD   F+ R++   +P  +++W+   Q+I     +      +   
Sbjct: 2943 PSFRHRLTAVE-VDEGDETRFDVRLK--KEP-TSVEWYKEQQRIFTDGHFEVIEGEEECL 2998

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             +L I  T   D+G Y C A N+ G++     L V
Sbjct: 2999 YSLVISNTKVADAGGYKCTALNESGKSSTRAELLV 3033



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 5/90 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSL 2833
            F   L  +   EGD   F+  ++  ++PT  +EW+   + + +   ++     +    SL
Sbjct: 2945 FRHRLTAVEVDEGDETRFDVRLK--KEPT-SVEWYKEQQRIFTDGHFEVIEGEEECLYSL 3001

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I++T   D+G Y C A N  G ++T   L
Sbjct: 3002 VISNTKVADAGGYKCTALNESGKSSTRAEL 3031



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 3/86 (3%)

Query: 2650 SYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRN 2709
            SY+ L EG  + L+A V  + +P  +I W+K+        +L  +      +L++  +  
Sbjct: 3049 SYE-LQEGDTITLDAVV--KGNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIP 3105

Query: 2710 DDSGIYTCKATNLLGEAVSTASIKIE 2735
             DSG+Y C   N +G A  + ++ +E
Sbjct: 3106 KDSGVYKCVLKNKVGTATKSFTVDVE 3131



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 6/114 (5%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            L+EGD    +  V+   +P+  I W+ +        +   +      +L + +   +DSG
Sbjct: 3052 LQEGDTITLDAVVK--GNPYPEIRWYKDEFLAMESKKLMLSVRDRKNSLTLYHVIPKDSG 3109

Query: 2181 TYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA-QGHSTRIE 2233
             Y C   NK+G A  + T+ V   ++  +    P    ++R++EA QG + R E
Sbjct: 3110 VYKCVLKNKVGTATKSFTVDVEAKKSKGI---IPEFFRQLRRVEAVQGSTARFE 3160



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 18/65 (27%), Positives = 32/65 (49%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P   + WYK+G+ +T S ++    +     + ++  + ED   Y   A NKLG+A     
Sbjct: 229 PKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFD 288

Query: 860 IRVAA 864
           ++V A
Sbjct: 289 VKVKA 293



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 40/155 (25%), Positives = 62/155 (40%), Gaps = 11/155 (7%)

Query: 3502 GEAVTTASMKVQG--KRNI--ILESQLPKGMEGTIDKIAALEGYSGTVDTLTP--EAESG 3555
            GE   T S++V+   ++N+  ++      G  GT   +A  +  SGT  ++      E  
Sbjct: 335  GELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARND--SGTAHSIAELQVQERS 392

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
              PE   +  D+         F+ R+        +VEW      +  G R     +   V
Sbjct: 393  TKPEIEDSLRDVSALPGERVKFKVRI--GGKPKPKVEWRKGKSVIEDGERFTIAEESDEV 450

Query: 3616 I-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
              L I  + + DAG Y C ATN  GEA    +L V
Sbjct: 451  FSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 2/69 (2%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLY 2581
            EG+     ARV   G P+   EW  +G  ++  +   T        L I     +D+GLY
Sbjct: 505  EGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLY 562

Query: 2582 MCKAINRAG 2590
             C A N++G
Sbjct: 563  RCTARNKSG 571



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 12/127 (9%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQ-------APICTTSLKNVEIKEGQR 1594
            I  S+++++GL +      R+K    DM  ++  Q       AP   + L+ VE  EG  
Sbjct: 551  IEESSRDDSGLYRCTA---RNKSGTADMTFQLDVQPKKPKGTAPEIVSELRPVEATEGDD 607

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
            A     +      T  +EW  N   +K   R       G V L I +   +D G YTC  
Sbjct: 608  AVLSCTISGKPVPT--IEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRADDQGDYTCIV 665

Query: 1655 INALGEA 1661
             N LG A
Sbjct: 666  RNELGSA 672



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 7/93 (7%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            P  V+  + +E   EG      C +  +PV      +EW KNG  V    R +     G 
Sbjct: 591  PEIVSELRPVE-ATEGDDAVLSCTISGKPVPT----IEWLKNGIRVKDSRRTKCDLVDGE 645

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            V L I    A+D G YTC   N +G+ E   +L
Sbjct: 646  VKLTIKTTRADDQGDYTCIVRNELGSAESKTKL 678



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 53/222 (23%), Positives = 85/222 (38%), Gaps = 45/222 (20%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF---G 3751
            P F  ++K  +   EG  V  D +VE  G P   I+W+          R   + +    G
Sbjct: 686  PEFRTKLKP-VKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVESGRFKVMEEEEEDG 742

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
              +L I  +   D G     ATN  G AT+ A +                     ++KE 
Sbjct: 743  LYSLVISKLQLDDTGTIKVVATNASGKATSRADL---------------------EVKER 781

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            E     +  +E PIV              V E   V  + RV  K +P   ++W+++G+ 
Sbjct: 782  EFAPEFEGDEEGPIV--------------VTEGNEVSIQLRV--KANPNADVDWFKDGRP 825

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYA-EDSGEYICRAVNDFGE 3912
            +    + R +   G      ++V + ED+G Y C A N  G+
Sbjct: 826  IYESTK-RDIKRRGEEHTLAIHVSSLEDTGVYKCEASNRLGK 866



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493
            EG++     R+     P L  EW+   ++L   SR           + +S    +DSG Y
Sbjct: 1582 EGDDLELTVRVRGKPQPEL--EWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMY 1639

Query: 3494 LCRAYNNYGEAVTTASMKVQGKRNI 3518
             C A N  G +  T ++ VQ K+ I
Sbjct: 1640 QCVARNKAGSSSRTFNLDVQKKKVI 1664



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/88 (28%), Positives = 40/88 (45%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   VE+L++ VP+  S+R     +     L +  +   DS TY   A N+ G A  S
Sbjct: 2770 GRPLPTVEFLKDEVPVFKSDRTELTSNGNRHTLYLSDLAVRDSATYKAVAKNKAGVARRS 2829

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLE 1825
              L V+ K  L+        +Q+++  E
Sbjct: 2830 VELLVKPKRGLKPGEAAPEIVQRLKACE 2857



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 5/101 (4%)

Query: 3554 SGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTIN--D 3611
            S +PP F    + + + E     F+ RL         VEW+   + + T    + I   +
Sbjct: 2939 SVSPPSFRHRLTAVEVDEGDETRFDVRL---KKEPTSVEWYKEQQRIFTDGHFEVIEGEE 2995

Query: 3612 FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
                 L I      DAG Y C A N  G+++   +L V  R
Sbjct: 2996 ECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 6/86 (6%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI--EDSSRITKTHDFGY 2433
            P F   L  ++ + EG    FD RL    +PT  VEW++ ++ I  +    + +  +   
Sbjct: 2943 PSFRHRLTAVE-VDEGDETRFDVRLKK--EPT-SVEWYKEQQRIFTDGHFEVIEGEEECL 2998

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             S+ IS+ +  D G Y C A N  G+
Sbjct: 2999 YSLVISNTKVADAGGYKCTALNESGK 3024



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 4/81 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV- 4031
            P F  ++++   +VE +  +F  ++   G+P  KVEWF  GK +    RF+      +  
Sbjct: 3236 PEFKERLKN-IKVVEGDEAQFSVRVK--GEPEPKVEWFKTGKKIKSHARFSSKAGEKHTY 3292

Query: 4032 AMNFGWVYPEDSGEYLCRATN 4052
             +    V  ED G Y C A+N
Sbjct: 3293 TLTISDVAMEDFGTYKCVASN 3313



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            L EG +      +T   +P   ++WYKDG  I  S+ I+        SL IM +  ED G
Sbjct: 3346 LNEGDDLRLVVSVT--GNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTG 3403

Query: 842  SYTVRAVNKLGEAISTASIRVAAR 865
                 A+N  G A  + ++ + ++
Sbjct: 3404 VIKCVAMNPAGSASKSFTVVIESK 3427



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 17/55 (30%), Positives = 24/55 (43%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P+   EWY + + ++   R ++    G  TL I    A D G Y C   N  G
Sbjct: 34   GTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTRAEDQGEYKCVLRNEHG 88



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 2/93 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+     P   + G  + L C +   G P   + W+ NG+ +T   +           
Sbjct: 201  PEFIDEERGPIDATTGDEVTLTCSVS--GKPKPSITWYKNGKLLTDSLKLDIRSSGERNW 258

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            + ++ A   DT  Y   A N LG A  +  V+V
Sbjct: 259  VTMLSAKPEDTALYKCEAENKLGKASRAFDVKV 291



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 2/74 (2%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576
            P E  EG  A     +   G P    EW  NG+ +K   R +     G V L I +  A+
Sbjct: 599  PVEATEGDDAVLSCTIS--GKPVPTIEWLKNGIRVKDSRRTKCDLVDGEVKLTIKTTRAD 656

Query: 2577 DAGLYMCKAINRAG 2590
            D G Y C   N  G
Sbjct: 657  DQGDYTCIVRNELG 670



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 3270 QQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329
            +Q  P T + E P  I ++Q   ++ EG +A+   + V    P+  ++W  +G K+    
Sbjct: 1362 KQSAPKT-TGEEPIIIRKLQ-AQEIDEGSTANLVCK-VTAAKPEPSIKWTRDGVKIRENS 1418

Query: 3330 RYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDST 3368
            R +   D     L I     ++ G Y+   TN+ G  S+
Sbjct: 1419 RIKMVFDGETCSLTIRDATLDDEGVYKVTLTNEYGTASS 1457



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 19/77 (24%), Positives = 37/77 (48%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            +EWF   + L   SR+   +      + +  +   D+G+Y C A N+ G ++ +  L V+
Sbjct: 1600 LEWFKYDRTLWKSSRINFKSRDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQ 1659

Query: 3651 GRQGIILEPQLPSHFKS 3667
             ++ I   P + +H  S
Sbjct: 1660 KKKVIGNAPDIITHLIS 1676



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 5/95 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR--FTSIFR-FGY 693
            P+F   L+ +  +EG +  F+ RI+    P  ++EW +    I  S R   T  +     
Sbjct: 1763 PEFKQKLRPLEVVEGSEAKFDVRIKSY--PKPEVEWYRGTTKITDSLRHQITEPYEGDDT 1820

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             SL +L+  ++D+  Y C A +  G    +A L V
Sbjct: 1821 YSLIILNTTMEDAAMYKCVAFNEAGKTTCRADLTV 1855



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHD--FGFVTLDINSVVANDAG 2579
            EG  A +   V   G P+ + EW     EL+ G R     D       L I +    D+G
Sbjct: 3540 EGDRAKFHVEVS--GKPAAKVEWLKGDQELRNGGRVSLEEDRETQMYFLTITNCKPTDSG 3597

Query: 2580 LYMCKAINRAG 2590
             Y C A N+AG
Sbjct: 3598 KYTCIARNKAG 3608



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVSLDITHTYEEDSGI 2845
            GD +   C+V  S  P   I W+ N K L    +   +S+ + ++V++       ED+ +
Sbjct: 216  GDEVTLTCSV--SGKPKPSITWYKNGKLLTDSLKLDIRSSGERNWVTM--LSAKPEDTAL 271

Query: 2846 YTCKATNSKGSATTSGSLRCTGDK 2869
            Y C+A N  G A+ +  ++    K
Sbjct: 272  YKCEAENKLGKASRAFDVKVKAPK 295



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG+++     V  +  P  +IEW  + K +       +        L I  +  +DSG+Y
Sbjct: 505  EGESVELVARV--TGKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSGLY 562

Query: 2847 TCKATNSKGSA 2857
             C A N  G+A
Sbjct: 563  RCTARNKSGTA 573



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 6/97 (6%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF--- 964
            +PEF+T +K  +   EG     + ++E  G     +EW +    +  S R          
Sbjct: 685  RPEFRTKLKP-VKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVESGRFKVMEEEEED 741

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            G  +L I  + + D G     A NA G+AT+ A+L +
Sbjct: 742  GLYSLVISKLQLDDTGTIKVVATNASGKATSRADLEV 778



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 5/95 (5%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD---Y 1367
            P+F   L  ++ VEG  V L+ +++  G     +EW+     I    RF+   E +    
Sbjct: 686  PEFRTKLKPVKAVEGEEVQLDVKVE--GYPKPDIEWYRGTTMIVESGRFKVMEEEEEDGL 743

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +L +  +  +D+G     ATN  G+A +   L V
Sbjct: 744  YSLVISKLQLDDTGTIKVVATNASGKATSRADLEV 778



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 18/75 (24%), Positives = 38/75 (50%), Gaps = 2/75 (2%)

Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
           +   EG ++  + R++   +P   ++W K+G+ I  S++     R    +L +   +++D
Sbjct: 795 IVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTKRDIKRRGEEHTLAIHVSSLED 852

Query: 706 SGEYTCRAVSATGVA 720
           +G Y C A +  G A
Sbjct: 853 TGVYKCEASNRLGKA 867



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 6/91 (6%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSG--TRYKSTHDFSYVS 2832
            + +S L  +  +EG+    +C       PT   EW  +   + S    +  +T D S  +
Sbjct: 886  IILSKLRPVETEEGEETKLKCTFTGKPAPTC--EWTRDGIRIRSSRMVQIDTTEDSS--T 941

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I  T  +D G+Y C   N  G+ +TS  +
Sbjct: 942  LIIKETTLDDEGLYKCTIKNDLGTVSTSAEV 972



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 17/55 (30%), Positives = 22/55 (40%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P+   EWY +G+      R  TT D    ++        D G Y C A N  G
Sbjct: 1693 GKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEYKCVATNPLG 1747



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++++   +   G P+  V W+ +GR V    + +T        L + +A   D G
Sbjct: 1875 VKEGDDLNISATIA--GKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932

Query: 1249 EYTVRAVNHLGSAHTSAIVRVI 1270
             Y   A N LG+   +  V+V+
Sbjct: 1933 SYKCEANNKLGTVTKTYNVKVM 1954



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 30/128 (23%), Positives = 49/128 (38%), Gaps = 4/128 (3%)

Query: 1149 GLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPT 1208
            G+Y+ T   +       +  I      +P+F Q + N      G+++  E ++E  G P 
Sbjct: 2032 GVYKCTIQNQHGSTTTTVQVIVTQRSIRPIFGQKMKNVEG-RIGEDVRFEIQVE--GTPV 2088

Query: 1209 MRVEWFHNGRSVTVGSRFKTYYDF-GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267
              V +      +  G R+    +  G   L I +    D GEY   AVN  G   +   +
Sbjct: 2089 PAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYL 2148

Query: 1268 RVIERSDI 1275
             V E   I
Sbjct: 2149 HVEEELTI 2156



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 6/94 (6%)

Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF- 1499
            +I+P F  + K++E  I G+ V FE ++E        V + +  + +  G R+  + +  
Sbjct: 2057 SIRPIFGQKMKNVEGRI-GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEEN 2113

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR 1533
            G   L I +   ED+G Y C AVN  G  EV+ +
Sbjct: 2114 GLFVLTIRNTRPEDAGEYQCIAVN--GAGEVTSK 2145



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GFI 3753
            P F  ++K N++   G  V F+ +VE  G P   + +         G R   + +  G  
Sbjct: 2060 PIFGQKMK-NVEGRIGEDVRFEIQVE--GTPVPAVTFHRESEQIYDGGRYSIVEEENGLF 2116

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATT 3781
             L I      DAGEY C A N  G  T+
Sbjct: 2117 VLTIRNTRPEDAGEYQCIAVNGAGEVTS 2144



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            E  V E +AR P +   L D V    GE A F  RV+G P P V W      I     Y 
Sbjct: 2637 ELTVLEREAR-PRILEKLQD-VDSSVGERAMFKIRVSGSPMPVVQWYRRDEEITTKGHYI 2694

Query: 4159 LTYDGMYHFDI 4169
            +  +G  +F +
Sbjct: 2695 VRDEGRGYFSL 2705



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 19/69 (27%), Positives = 33/69 (47%)

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
            G+    ++W+ +G  I+       +      +L ++ V PED+GV  C A N  G A  S
Sbjct: 3360 GNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKS 3419

Query: 1398 CALRVIAKK 1406
              + + +KK
Sbjct: 3420 FTVVIESKK 3428



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 2499 EEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR 2558
            E  +REF  P F     GP  + EG     + RV    +P+   +W+ +G  +   ++  
Sbjct: 777  EVKEREFA-PEFEGDEEGPIVVTEGNEVSIQLRVK--ANPNADVDWFKDGRPIYESTKRD 833

Query: 2559 TTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                    TL I+     D G+Y C+A NR G
Sbjct: 834  IKRRGEEHTLAIHVSSLEDTGVYKCEASNRLG 865



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 2/102 (1%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            +EV+T  P F M   +  + + +    E  +   G P+  +EW +    +  S+R+    
Sbjct: 1562 NEVLT-VPEF-MDKAEGPIEKTEGDDLELTVRVRGKPQPELEWFKYDRTLWKSSRINFKS 1619

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
                  + +  +  +DSG Y C A N+ G +  +  L VQ K
Sbjct: 1620 RDNKFTMTVSDLGLDDSGMYQCVARNKAGSSSRTFNLDVQKK 1661



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 2/93 (2%)

Query: 1572 EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNN 1631
            +V   AP   T L + E+KEG     E  +         +EWY +     +  R   T +
Sbjct: 1662 KVIGNAPDIITHLISKEVKEGGTVTLECTVS--GKPAPNIEWYKDGLRFTATRRVMTTFD 1719

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
                ++        D G Y C A N LG A +S
Sbjct: 1720 GSVASVTFTDAQGFDDGEYKCVATNPLGSAQSS 1752



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 768  QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRIT-SIFNFG 826
            Q P F   +  + E+ EG        ++    PT  V+W +DG P+    RI+       
Sbjct: 1961 QAPSFTSEMSQV-EVDEGGEVKLYFLISGYPKPT--VKWTRDGIPVFEDYRISMDSSRVQ 2017

Query: 827  YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
             V+L I ++   D G Y     N+ G   +T  + V  RS
Sbjct: 2018 GVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRS 2057



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 3/77 (3%)

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIVILDILYCYEENSGEY 3355
            G+   FE ++     P   V +    +++  G RY    +  G+ +L I     E++GEY
Sbjct: 2074 GEDVRFEIQVEGTPVP--AVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEY 2131

Query: 3356 ECVATNKLGRDSTKANL 3372
            +C+A N  G  ++K  L
Sbjct: 2132 QCIAVNGAGEVTSKGYL 2148



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 5/91 (5%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKV-EWYHNNKPLKS-GSRFTETNNFGFV 1635
            P     L++V+   G+RA F+ R   VS + + V +WY  ++ + + G         G+ 
Sbjct: 2647 PRILEKLQDVDSSVGERAMFKIR---VSGSPMPVVQWYRRDEEITTKGHYIVRDEGRGYF 2703

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666
            +L I     ED G Y    IN  GE  ++ +
Sbjct: 2704 SLTIEYIDYEDEGAYKAVVINDSGEVSSTAV 2734



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/91 (27%), Positives = 37/91 (40%), Gaps = 3/91 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P  V R K+ E V EG      C++         +EW+K+  P+    R    H      
Sbjct: 2847 PEIVQRLKACE-VPEGSSFKLRCRVTGTPTPT--IEWYKSNMPLKPNGRVIIGHTGDQYF 2903

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L+ ++  A D G Y   A N +G+   S  L
Sbjct: 2904 LNFLETEARDEGRYMLVAKNHLGSVSTSAEL 2934



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 35/150 (23%), Positives = 56/150 (37%), Gaps = 11/150 (7%)

Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578
            E+ EG       RV   G P+   EWY + + LK   R    H      L+     A D 
Sbjct: 2857 EVPEGSSFKLRCRVT--GTPTPTIEWYKSNMPLKPNGRVIIGHTGDQYFLNFLETEARDE 2914

Query: 2579 GLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGV 2638
            G YM  A N  G               II+ ++ P S+   +L    +++  E   D  +
Sbjct: 2915 GRYMLVAKNHLG-------SVSTSAELIIEPSVSPPSFRH-RLTAVEVDEGDETRFDVRL 2966

Query: 2639 QQAPIFTTHLKSYDKL-VEGQHVYLEAQVE 2667
            ++ P      K   ++  +G    +E + E
Sbjct: 2967 KKEPTSVEWYKEQQRIFTDGHFEVIEGEEE 2996



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 2/74 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EGD++    +V  + +P   ++W+ +   +   T    +   S  SL I     ED+G+ 
Sbjct: 3348 EGDDLRLVVSV--TGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVI 3405

Query: 2847 TCKATNSKGSATTS 2860
             C A N  GSA+ S
Sbjct: 3406 KCVAMNPAGSASKS 3419



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 2397 DCRLIP--VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRAS 2454
            D RL+    G+P   ++W+++  LI  S+ I+ +      S+ I  V  ED GV  C A 
Sbjct: 3351 DLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYSLAIMGVVPEDTGVIKCVAM 3410

Query: 2455 NLLG 2458
            N  G
Sbjct: 3411 NPAG 3414



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 7/133 (5%)

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLK--VTQPDQADNLPALTP-----LRDIVVYEGQPAQF 4740
            EDE D +      A       K++  V++P + +  PA  P     L D  V EG+    
Sbjct: 4611 EDELDAEPTEVEPAPAEPTPTKIQTEVSKPSKREPAPAPKPVFASELIDKQVKEGENLSL 4670

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
              ++  + K  + W R+   + +     +I  G+   L I     +D   +   AT A+G
Sbjct: 4671 DVKLPQEYKAEVAWYRDDKKLEDDHRITIIAAGDLHCLTIFGVSIKDEAVYKVVATNASG 4730

Query: 4801 QVETSAKLVVKSK 4813
                  +++V+ +
Sbjct: 4731 TTSCDCEVLVEER 4743



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 1/67 (1%)

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL-TYDGMYHFDIPKTRQYD 4176
            + V V+E E A   C ++G P P   W  +   +    R K    +GM    I +TR  D
Sbjct: 16   EGVDVKEDENAILSCTISGTPTPNAEWYRDSIRVRESRRIKSEVVNGMATLTIKQTRAED 75

Query: 4177 TGKIEVI 4183
             G+ + +
Sbjct: 76   QGEYKCV 82



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566
            KP     L   S L  G+   ++ R+   G P  + EW      ++ G RF    +   V
Sbjct: 394  KPEIEDSLRDVSAL-PGERVKFKVRIG--GKPKPKVEWRKGKSVIEDGERFTIAEESDEV 450

Query: 2567 -TLDINSVVANDAGLYMCKAINRAG 2590
             +L I  +   DAG Y C A N AG
Sbjct: 451  FSLIIQDLEETDAGRYKCVATNEAG 475



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 5/91 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK---STHDFSYVS 2832
            F + L  +   EG+ +  +  VE    P   IEW+     +    R+K      +    S
Sbjct: 688  FRTKLKPVKAVEGEEVQLDVKVEGYPKPD--IEWYRGTTMIVESGRFKVMEEEEEDGLYS 745

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            L I+    +D+G     ATN+ G AT+   L
Sbjct: 746  LVISKLQLDDTGTIKVVATNASGKATSRADL 776



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 4/133 (3%)

Query: 1139 SSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLE 1198
            SS++ + +++      R  + S+  +   Q++      P+ +  L  P    EG+   L+
Sbjct: 848  SSLEDTGVYK-CEASNRLGKASRSFDVKVQVKGPKGEAPIILSKL-RPVETEEGEETKLK 905

Query: 1199 CRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHL 1258
            C     G P    EW  +G  +      +         L I   T  D G Y     N L
Sbjct: 906  CTFT--GKPAPTCEWTRDGIRIRSSRMVQIDTTEDSSTLIIKETTLDDEGLYKCTIKNDL 963

Query: 1259 GSAHTSAIVRVIE 1271
            G+  TSA V V E
Sbjct: 964  GTVSTSAEVLVNE 976



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 5/94 (5%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD--FGY 4030
            P F  ++++  S +E E+T+FE +L+ +  P   VEWF +   +    RFT   +   G 
Sbjct: 1470 PIFQQKLKA-VSTIEGESTRFEVKLSAM--PRPTVEWFKSSSQIYDGGRFTITEEENSGV 1526

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064
              +       ED+G Y   A N  G   ++A+++
Sbjct: 1527 YVLVIEDTNIEDAGTYKVVAYNNLGKVTSQALLR 1560



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 5/80 (6%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF---GFVALDIM 1640
            L+ +E+ EG  A F+ R+   S    +VEWY     +    R   T  +      +L I+
Sbjct: 1769 LRPLEVVEGSEAKFDVRI--KSYPKPEVEWYRGTTKITDSLRHQITEPYEGDDTYSLIIL 1826

Query: 1641 SCLPEDSGTYTCRAINALGE 1660
            +   ED+  Y C A N  G+
Sbjct: 1827 NTTMEDAAMYKCVAFNEAGK 1846



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491
            ++EG++ +  A  T    P+ +V WY +G+ +    +  T        L +     ED+G
Sbjct: 1875 VKEGDDLNISA--TIAGKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAG 1932

Query: 3492 EYLCRAYNNYGEAVTTASMKV 3512
             Y C A N  G    T ++KV
Sbjct: 1933 SYKCEANNKLGTVTKTYNVKV 1953



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 3/88 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W ++G  +  S +  T        L +     ED+G+Y C A N+LG    +
Sbjct: 1889 GKPSPEVSWYKDGRLVLDSIKQETRKRGDESHLVVFNAKMEDAGSYKCEANNKLGTVTKT 1948

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLE 1825
              + V S A    E Q  S   ++ Q+E
Sbjct: 1949 YNVKVMSTAP---EGQAPSFTSEMSQVE 1973



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 5/94 (5%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYV 1368
            P F   L  +E  EG     + RL+    +   VEW+   + I T   F      E    
Sbjct: 2943 PSFRHRLTAVEVDEGDETRFDVRLKK---EPTSVEWYKEQQRIFTDGHFEVIEGEEECLY 2999

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +L + +    D+G Y C A N+ G++ T   L V
Sbjct: 3000 SLVISNTKVADAGGYKCTALNESGKSSTRAELLV 3033



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNN-KPLPSGTRYKSTHDFSYVSLDITHTYEEDSG 2844
            +EGD I  +  V+ +  P  +I W+ +    + S     S  D    SL + H   +DSG
Sbjct: 3053 QEGDTITLDAVVKGNPYP--EIRWYKDEFLAMESKKLMLSVRDRKN-SLTLYHVIPKDSG 3109

Query: 2845 IYTCKATNSKGSATTS 2860
            +Y C   N  G+AT S
Sbjct: 3110 VYKCVLKNKVGTATKS 3125



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 2/105 (1%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            V+E      + T  L     L EG++      +T    P+L  +WY +G  ++  +    
Sbjct: 3326 VKERMVPPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDL--QWYKDGVLIRRSTHISL 3383

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
                    L I    PED+G   C A N  G A  + ++ ++ K+
Sbjct: 3384 SSIGSRYSLAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKK 3428



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 5/109 (4%)

Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLR 2541
            E   K+ K  +  + + + P  + + P FT  LT    + EG+ +    +V   G P+  
Sbjct: 275  EAENKLGKASRAFDVKVKAP--KGDAPSFTIDLTHVRAI-EGEESKLVCKVT--GKPAPT 329

Query: 2542 FEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             EW    + +    R RT  +    TL I      DAG Y   A N +G
Sbjct: 330  IEWLKGELPVTTSLRVRTDFEKNVATLVIKDTRLGDAGTYKVVARNDSG 378



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 13/109 (11%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDF-GFVTLDLV--DVYE 2978
            ++VEG     + ++  K+ P  ++EWY     +    R ++T  + G  T  L+  +   
Sbjct: 1773 EVVEGSEAKFDVRI--KSYPKPEVEWYRGTTKITDSLRHQITEPYEGDDTYSLIILNTTM 1830

Query: 2979 RDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPK--GTEGLEKI 3025
             D+ +Y C A+N+ G+        C +   +IE+ Q P   G +G + I
Sbjct: 1831 EDAAMYKCVAFNEAGK------TTCRADLTVIEKQQPPTFLGDDGTQTI 1873



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/85 (23%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 636  PPQFIVP--LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
            PP F+     +++   EG  ++    I   G P+ ++ W K+G+ +  S +  +  R   
Sbjct: 1861 PPTFLGDDGTQTIIVKEGDDLNISATI--AGKPSPEVSWYKDGRLVLDSIKQETRKRGDE 1918

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATG 718
              L + +  ++D+G Y C A +  G
Sbjct: 1919 SHLVVFNAKMEDAGSYKCEANNKLG 1943



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 32/127 (25%), Positives = 48/127 (37%), Gaps = 8/127 (6%)

Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475
            +G+AP FT  +S +E + EG        ++    P +K    W    +     +R   D 
Sbjct: 1959 EGQAPSFTSEMSQVE-VDEGGEVKLYFLISGYPKPTVK----WTRDGIPVFEDYRISMDS 2013

Query: 3476 GFV---ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTI 3532
              V    L I      D G Y C   N +G   TT  + V  +    +  Q  K +EG I
Sbjct: 2014 SRVQGVTLIIRNVTRYDEGVYKCTIQNQHGSTTTTVQVIVTQRSIRPIFGQKMKNVEGRI 2073

Query: 3533 DKIAALE 3539
             +    E
Sbjct: 2074 GEDVRFE 2080



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 14/112 (12%)

Query: 1172 ISKSKPVFVQPLSNPPP---------VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            +S S  + ++P  +PP          V EG     + RL+   +PT  VEW+   + +  
Sbjct: 2928 VSTSAELIIEPSVSPPSFRHRLTAVEVDEGDETRFDVRLKK--EPTS-VEWYKEQQRIFT 2984

Query: 1223 GSRFKTYY--DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
               F+     +    +L I +   AD G Y   A+N  G + T A + V ER
Sbjct: 2985 DGHFEVIEGEEECLYSLVISNTKVADAGGYKCTALNESGKSSTRAELLVNER 3036



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 17/64 (26%), Positives = 28/64 (43%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T  W+   +++ S  RI         +L I  ++  D G Y +V +N  GE      +TV
Sbjct: 5996 TATWFRGDEELKSGGRIHIETTDDRSSLTIERIQFRDEGEYELVVKNDGGEDSCVVKLTV 6055

Query: 1136 ETRS 1139
            +  S
Sbjct: 6056 DDDS 6059



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 7/116 (6%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   + W+ NGK L    +           + +L    E++  Y+C A NKLG+ S   +
Sbjct: 229  PKPSITWYKNGKLLTDSLKLDIRSSGERNWVTMLSAKPEDTALYKCEAENKLGKASRAFD 288

Query: 3372 LKCTSKE----NLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFT 3423
            +K  + +    +  +D    R +EG   KL      +  +   ++E  KG+ PV T
Sbjct: 289  VKVKAPKGDAPSFTIDLTHVRAIEGEESKLVC---KVTGKPAPTIEWLKGELPVTT 341



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 4/95 (4%)

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            KP     L+  + +  G+   F+ R+  +      VEW      I    R     +   V
Sbjct: 394  KPEIEDSLRDVSAL-PGERVKFKVRIGGKPK--PKVEWRKGKSVIEDGERFTIAEESDEV 450

Query: 1102 -ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             +L I  +   D+G Y  VA N AGEA+  A +TV
Sbjct: 451  FSLIIQDLEETDAGRYKCVATNEAGEAESMAQLTV 485



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 2/96 (2%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+F    +    + EG     + R+    +P+  V+WF +G+ +    +           
Sbjct: 785  PEFEGDEEGPIVVTEGNEVSIQLRVKA--NPNADVDWFKDGRPIYESTKRDIKRRGEEHT 842

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
            L I     E++G Y+C A+N+LG+ S   ++K   K
Sbjct: 843  LAIHVSSLEDTGVYKCEASNRLGKASRSFDVKVQVK 878



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 5/114 (4%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P     ++  E  EG    L+ T T    PT   EW  +G  ++     +        
Sbjct: 883  EAPIILSKLRPVETEEGEETKLKCTFTGKPAPTC--EWTRDGIRIRSSRMVQIDTTEDSS 940

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDEQRLKKI 2088
             L I     +D G Y C   N +G   T++ V V + + G  +  + E++LK +
Sbjct: 941  TLIIKETTLDDEGLYKCTIKNDLGTVSTSAEVLVNEVEKG--VGPVIEEKLKDV 992



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/92 (21%), Positives = 36/92 (39%), Gaps = 2/92 (2%)

Query: 4122 VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTGKI 4180
            V+EG      C V+G P P + W  +G       R   T+DG +        + +D G+ 
Sbjct: 1679 VKEGGTVTLECTVSGKPAPNIEWYKDGLRFTATRRVMTTFDGSVASVTFTDAQGFDDGEY 1738

Query: 4181 EVIXXXXXXXXXXXXXLKV-IPRHDDYRGVLK 4211
            + +             L V +P   +++  L+
Sbjct: 1739 KCVATNPLGSAQSSARLTVTVPSKPEFKQKLR 1770



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/101 (24%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT-ETNNFGF 1634
            QAP  T+ +  VE+ EG        +      T+K  W  +  P+    R + +++    
Sbjct: 1961 QAPSFTSEMSQVEVDEGGEVKLYFLISGYPKPTVK--WTRDGIPVFEDYRISMDSSRVQG 2018

Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
            V L I +    D G Y C   N  G   T+ + ++ +++SI
Sbjct: 2019 VTLIIRNVTRYDEGVYKCTIQNQHGSTTTT-VQVIVTQRSI 2058



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            IV  EG     +  +  +  P  ++ W+ + K      R       +   L IT+   ED
Sbjct: 2461 IVVPEGGETTLKVTLRANPKP--QVIWYKDGKHTSENIRLDVRSRGNTHYLKITNAKIED 2518

Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864
            SG Y C+A N  G A  S ++R
Sbjct: 2519 SGSYKCEARNKLGFADKSFTIR 2540



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/100 (23%), Positives = 40/100 (40%), Gaps = 3/100 (3%)

Query: 65   RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
            R  + +P   EQ  K+    + G A  E +  G+    + W + +  +    +  M  + 
Sbjct: 4757 RLSQVAPEFMEQC-KSTTVQENGTAIMEVRATGSQPLSIRWFKNQQTIKYGGRIKMSSDG 4815

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            +    +L I  +   DEG Y C   N+ G A C   +  E
Sbjct: 4816 E--HCTLKISPVEKKDEGLYMCVISNKAGTADCEALLTVE 4853



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 2/73 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG+++ L  R+   G P   +EW  +G++V   +   T        L I  ++  D+G
Sbjct: 503  VVEGESVELVARVT--GKPAPEIEWTKDGKTVRKTNNVDTKERDDQAVLTIEESSRDDSG 560

Query: 1249 EYTVRAVNHLGSA 1261
             Y   A N  G+A
Sbjct: 561  LYRCTARNKSGTA 573



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 6/95 (6%)

Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH--KN 4020
            DL   +++  P F  +   +  +V  E  +   QL    +PN  V+WF +G+P+    K 
Sbjct: 775  DLEVKEREFAPEF--EGDEEGPIVVTEGNEVSIQLRVKANPNADVDWFKDGRPIYESTKR 832

Query: 4021 RFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
                  +   +A++   +  ED+G Y C A+N  G
Sbjct: 833  DIKRRGEEHTLAIHVSSL--EDTGVYKCEASNRLG 865



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 5/87 (5%)

Query: 1041 QKPRFLGPLKGTNKIV--EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF 1098
            Q P FLG   GT  I+  EG   +  A +  +   +  V WY +G+ +  + + +T    
Sbjct: 1860 QPPTFLGD-DGTQTIIVKEGDDLNISATIAGKP--SPEVSWYKDGRLVLDSIKQETRKRG 1916

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAG 1125
                L + + + ED+G Y   A N  G
Sbjct: 1917 DESHLVVFNAKMEDAGSYKCEANNKLG 1943



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 14/37 (37%), Positives = 19/37 (51%)

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            G   LTI++    DAG Y C A N  G+ T+   L +
Sbjct: 2114 GLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHV 2150



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 2/72 (2%)

Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578
            E  +G  A +E +V   G P  +  W  +G EL +    +  +D     L        D 
Sbjct: 3150 EAVQGSTARFECKVS--GHPEPQIAWLKDGKELAIPRYIKPFYDGEVCKLTFYETQPEDE 3207

Query: 2579 GLYMCKAINRAG 2590
            G Y C A N AG
Sbjct: 3208 GDYTCVASNEAG 3219



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 3/100 (3%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+  T +       +EG      V    +P   ++WY++G L+               S
Sbjct: 3332 PPEISTDVLEGPALLNEGDDLRLVVSVTGNPIPDLQWYKDGVLIRRSTHISLSSIGSRYS 3391

Query: 3889 LDILYVYAEDSGEYICRAVNDFG---EDFTKATISCKKLP 3925
            L I+ V  ED+G   C A+N  G   + FT    S K  P
Sbjct: 3392 LAIMGVVPEDTGVIKCVAMNPAGSASKSFTVVIESKKPAP 3431


>SB_8818| Best HMM Match : I-set (HMM E-Value=0)
          Length = 2787

 Score =  199 bits (486), Expect = 4e-50
 Identities = 166/603 (27%), Positives = 266/603 (44%), Gaps = 33/603 (5%)

Query: 4219 DETTQYQRTET-ELEKTFEERQVLQRQGVIDH--RPELKPKVIKEPETEWQQSVKRKKNE 4275
            D+   Y+   T EL  T    ++L  +  ++   +PE KPKV K PE E +  V++ + E
Sbjct: 988  DDEGDYKCVATNELGSTSATTELLVNEKPVEEEKQPE-KPKVEK-PEVE-EPEVEKPEVE 1044

Query: 4276 EYYNKLQELENEQ-VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTE--EV 4332
            E  +   E+E     + +  L   T +          +      A +  D L   E  E 
Sbjct: 1045 EPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKPTGEAPKVVDALQPLEALEG 1104

Query: 4333 TEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEI-TRKITSTETTEIE 4391
             E ++  K+T  P  P         K V V + K    + V    I T +       +  
Sbjct: 1105 DEAKLVCKITGSPT-PTVEWFKEKAKVVDVRRTKMEYTDDVATLTIPTTRPEDKGMYKCV 1163

Query: 4392 HKAQTQERVVEGP--VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENF 4449
             K    E        + P   P F  K++P  V E   A+FEV   G P P ++W+  + 
Sbjct: 1164 AKNDFGEASTSATLHINPVVKPDFKTKLKPMEVTEESVAKFEVRSTGFPQPEVEWFLGST 1223

Query: 4450 PIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRG 4509
             I++S  F++ +   +  LII  V V+D+  +     N+ GTA   A+L V+EK      
Sbjct: 1224 KIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK------ 1277

Query: 4510 GIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
               P      A  + V  G+ + +  ++T     +V W K+GK ++   R  I   D  Y
Sbjct: 1278 DCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVKWYKDGKPLRDGPRTTIRARDDLY 1337

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
               +L A P+D+G Y+C A N+ G+A    +  V +P    KP+       + P +   L
Sbjct: 1338 NCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVEVP----KPR------GSKPSLEAEL 1387

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
            K   V  G+  +  CKI GKP P + W K DK +KP K    +   +   L   +A  ED
Sbjct: 1388 KPVTVTAGEDTKLVCKISGKPQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLED 1447

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749
            E +YK VA N  G V+ +A+L V +   A  +    PL+D+ V  G+ A F TQ++    
Sbjct: 1448 EAEYKVVAKNELGSVSTSAELLVNEKGAAPKIE--KPLQDVKVDAGKKATFNTQVSGTPT 1505

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            P ++W +  +++ +   F +I +    V  L+I +   ED+G + C      G+ +T AK
Sbjct: 1506 PEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAK 1565

Query: 4808 LVV 4810
            L V
Sbjct: 1566 LQV 1568



 Score =  193 bits (471), Expect = 3e-48
 Identities = 122/449 (27%), Positives = 213/449 (47%), Gaps = 24/449 (5%)

Query: 4365 QKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFE 4424
            ++ T K +  +++   +     T E+     T E +V+  ++    P F +KMQP +V E
Sbjct: 80   ERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVKETLRK---PEFKQKMQPLQVLE 136

Query: 4425 HEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484
             ++ RF+V  DG+P P ++W++    I N   F+I        LII    + D+  +  +
Sbjct: 137  GDEVRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADTYKCI 196

Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
            A +  G + C   L V+EK         P  F  TA  +N+T G  + L  +V G    +
Sbjct: 197  ATSEAGKSTCIVELSVKEKTS------APEVFGDTAP-INITEGDELDLSVRVRGKPKPE 249

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            + W K+ K ++   R     +D    L++ +A P+DSG+Y+C A +  G A  + +  V 
Sbjct: 250  IKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVE 309

Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
                K KPK         P+  +PL+   + E +     C + G+P PT +W KGD+ +K
Sbjct: 310  ----KAKPK------GVAPKFTKPLETLEIMEKETARLECTVTGEPAPTTEWLKGDQPLK 359

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
             ++  ++ R  D   L +     +DE  YK VA N +G  T  A+L V +  +       
Sbjct: 360  ETQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKK- 418

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMI--HEGNNAVLLIGN 4782
            TP +++ V EG   +   ++  K +PT+ W +    + E   F ++   EG+   L+IGN
Sbjct: 419  TP-QNVTVLEGDEIRLDARVGGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGN 477

Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                D+G + C+AT   G+    A++ ++
Sbjct: 478  AKPLDSGVYICQATNDTGKATAEAEIQIE 506



 Score =  174 bits (423), Expect = 2e-42
 Identities = 109/412 (26%), Positives = 187/412 (45%), Gaps = 25/412 (6%)

Query: 4406 KPS-KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            KP+ + P  T+ +Q     E        +F G P P+ +W++ + P+++   ++I T   
Sbjct: 625  KPAGEAPEITESLQEMEELEGNPVTLTCKFTGTPAPVAEWFKASTPVRDGRRYKITTTDN 684

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
             + L I++  ++D+  +  V  N  G+ K    + +          +V P FT   + V 
Sbjct: 685  TTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRIT--------ALVRPDFTKKLKPVE 736

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V  GQ  RLD +V GT   +V W     K+    R + +EE  +YTL+I      D   Y
Sbjct: 737  VEEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTY 796

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIV-AEGQAIEF 4642
            +CVA N  G+  C  +  V+                 PPEI  P + +KIV  E + +  
Sbjct: 797  KCVASNQVGKVTCRGDLKVT-------------EKMFPPEITRPERTEKIVLLEKEELVI 843

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
            +  I+G P P V+W+K  K I+ S    +    D YTL I    PED G Y C A N  G
Sbjct: 844  NVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG 903

Query: 4703 RVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
              +    +++         P+L + L+   + EG+ A+ + +++ + +PTI+W ++   +
Sbjct: 904  TSSTTIDVQIEASKPKGEAPSLVSELQPQEISEGEDAKLECKVSGEPQPTIEWFKDDEPV 963

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                  +  ++G  + L I +   +D G + C AT   G    + +L+V  K
Sbjct: 964  TTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK 1015



 Score =  168 bits (409), Expect = 8e-41
 Identities = 109/405 (26%), Positives = 186/405 (45%), Gaps = 21/405 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FTKK+QP  V E E+   +    G+P P ++W  +   +++    +      +  L I
Sbjct: 27   PEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTLKI 86

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                 +D   +  VA N  G A  +  ++V+E  R+       P F    Q + V  G  
Sbjct: 87   MPSERDDEGEYKCVATNEVGQATITTEVLVKETLRK-------PEFKQKMQPLQVLEGDE 139

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            VR D ++ G     V W KN  K+  + R +I++E+  Y+L+I +    D+  Y+C+A +
Sbjct: 140  VRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADTYKCIATS 199

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
             AG++ C  E  V         K +T A    PE+        + EG  ++ S ++ GKP
Sbjct: 200  EAGKSTCIVELSV---------KEKTSA----PEVFGDTAPINITEGDELDLSVRVRGKP 246

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P ++W K DK IK +     +   DE  L +S+A PED G YKC A +  G  +    +
Sbjct: 247  KPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDV 306

Query: 4711 KVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
             V +       P  T PL  + + E + A+ +  +T +  PT +WL+    + ET   ++
Sbjct: 307  NVEKAKPKGVAPKFTKPLETLEIMEKETARLECTVTGEPAPTTEWLKGDQPLKETQRIKI 366

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
              + ++ VL + +   +D   +   A   +G   + A+L+V   T
Sbjct: 367  ERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEAT 411



 Score =  168 bits (408), Expect = 1e-40
 Identities = 175/743 (23%), Positives = 300/743 (40%), Gaps = 59/743 (7%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            +T E +V+E+  +  P F      + V EG+  RF  R+ G P P+V W  N   I N  
Sbjct: 110  ITTEVLVKETLRK--PEFKQKMQPLQVLEGDEVRFDVRIDGKPTPKVEWFKNRTKIDNEG 167

Query: 4156 RYK-LTYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAP 4214
            R++ +  + +Y   I  TR  D    + I             L V  +         +AP
Sbjct: 168  RFEIIDEEDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEK--------TSAP 219

Query: 4215 RPWYDETTQYQRTE-TELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKK 4273
               + +T     TE  EL+ +   R           +PE+K     +P  +  +     K
Sbjct: 220  EV-FGDTAPINITEGDELDLSVRVRG--------KPKPEIKWTKDDKPIKKTDRLTTTTK 270

Query: 4274 NEEYYNKLQELENEQVIKESRLRESTHQYAIPG-DKVTSNTVAKSMAQRYEDNLDQTEEV 4332
            ++E    L + + E   +     +S H  A    D        K +A ++   L +T E+
Sbjct: 271  DDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPL-ETLEI 329

Query: 4333 TEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQK-EVVGDKE-ITRKITSTE-TTE 4389
             E+   +        P P+   + G +      K+TQ+ ++  DK+ +  ++   E   E
Sbjct: 330  MEKETARLECTVTGEPAPTTEWLKGDQ----PLKETQRIKIERDKDSVVLEVRHVELDDE 385

Query: 4390 IEHK--AQTQERVVEGPV-----KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
              +K  A+ +  V          + ++ P F K  Q   V E ++ R +    G+P P +
Sbjct: 386  ALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLEGDEIRLDARVGGKPEPTV 445

Query: 4443 KWYRENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             W++ +  +     F I       +  LII      DS V+   A N  G A   A + +
Sbjct: 446  DWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 505

Query: 4501 EEKRRQGRGGIVPPSFT-LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIR 4559
            EE        +V P F    A  + +     + L+  VTG    +V+W K+ K +  D R
Sbjct: 506  EEL-------LVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDR 558

Query: 4560 NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE------ARCDAECVVSLPATKDKPK 4613
              I  +  +  + I+   P DSG Y+C A N AG          +   V  +       +
Sbjct: 559  IIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEVLFVAGISQVIGSIR 618

Query: 4614 ---PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
                  K A   PEI E L++    EG  +  +CK  G P P  +W+K    ++  + ++
Sbjct: 619  FIVLAKKPAGEAPEITESLQEMEELEGNPVTLTCKFTGTPAPVAEWFKASTPVRDGRRYK 678

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            ++ T +  TL I E   +D  +Y+ V  N  G V    ++++T   + D    L P   +
Sbjct: 679  ITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKP---V 735

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EGQ A+   ++     P ++W      + +T  ++ I EG++  L+I  T  +D  T
Sbjct: 736  EVEEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDT 795

Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813
            + C A+   G+V     L V  K
Sbjct: 796  YKCVASNQVGKVTCRGDLKVTEK 818



 Score =  168 bits (408), Expect = 1e-40
 Identities = 195/804 (24%), Positives = 331/804 (41%), Gaps = 89/804 (11%)

Query: 3947 EATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMK 4006
            EA  K  TS   +         K + P  V+++Q Q  + E E  K EC+++  G+P   
Sbjct: 897  EAQNKMGTSSTTIDVQIEASKPKGEAPSLVSELQPQ-EISEGEDAKLECKVS--GEPQPT 953

Query: 4007 VEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
            +EWF + +P+   NR    YD     +       +D G+Y C ATN  G       +   
Sbjct: 954  IEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVN 1013

Query: 4067 GKPGIVYDSQLPKHMK----SIEK--IREMEASWQVTPEQVVEESKARCP-----PVFVS 4115
             KP  V + + P+  K     +E+  + + E    V+ +  VE      P     PV V 
Sbjct: 1014 EKP--VEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVE 1071

Query: 4116 LPDA--VTVE---------------------EGEWARFCCRVTGHPKPRVMWLLNGNTIV 4152
            + +   +T+E                     EG+ A+  C++TG P P V W      +V
Sbjct: 1072 VVETAPITLEDMKPTGEAPKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVV 1131

Query: 4153 NGSRYKLTY-DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIP-RHDDYRGVL 4210
            +  R K+ Y D +    IP TR  D G  + +             L + P    D++  L
Sbjct: 1132 DVRRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHINPVVKPDFKTKL 1191

Query: 4211 KNAPRPWYDETTQYQRTETELEKT-FEERQVLQRQGVIDHRPELKPKVIKEPETEWQ--Q 4267
            K        E T+    + E+  T F + +V    G        + +V+ E +       
Sbjct: 1192 KPM------EVTEESVAKFEVRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIIS 1245

Query: 4268 SVKRKKNEEYYNKLQELENEQVIK-ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNL 4326
             VK K    Y   L         + + +++E        GD+      A  +  R  +++
Sbjct: 1246 DVKVKDAGTYKCTLANQAGTAYSRADLKVKEKDCAPEFVGDQ------AAPIVVRQGEDI 1299

Query: 4327 DQTEEVT---EQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKIT 4383
            D   ++T   +  V+     KP + D   +T+  ++          K +    E T    
Sbjct: 1300 DIGAQITAKPKPNVKWYKDGKP-LRDGPRTTIRARD-----DLYNCKVLSAKPEDTGMYK 1353

Query: 4384 STETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIK 4443
               T  +    +T +  VE P      P    +++P  V   E  +   +  G+P P I 
Sbjct: 1354 CEATNAVGKATRTFDVQVEVPKPRGSKPSLEAELKPVTVTAGEDTKLVCKISGKPQPKID 1413

Query: 4444 WYRENFPIKNSPDFQI-HTFSTKS-ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            W +++ P+K  PD ++  T+  ++ +L   +  +ED A +  VA+N  G+   SA L+V 
Sbjct: 1414 WMKDDKPLK--PDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVN 1471

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            EK          P      Q+V V +G+    +T+V+GT   +V W K    V+   R  
Sbjct: 1472 EKG-------AAPKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFM 1524

Query: 4562 ILEE--DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            I+++  +G + L+I +A P+DSG Y+CV  N  GE +  A+  + + A +  PK   K  
Sbjct: 1525 IIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAK--LQVDAVEVAPKTDKKL- 1581

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEY 4678
                E  EP+    V E Q ++ S K+ GK +P  V W+K D  +K +   ++      Y
Sbjct: 1582 ---DEKEEPI---TVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMY 1635

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAG 4702
             L +++A  +D G Y+C +    G
Sbjct: 1636 YLTLTDASLDDAGHYRCESTTKLG 1659



 Score =  168 bits (408), Expect = 1e-40
 Identities = 124/489 (25%), Positives = 218/489 (44%), Gaps = 34/489 (6%)

Query: 4332 VTEQRVQK-KVTQKPRI--PDPSESTVHGKEVHVAKQKQTQKEV-VGDKEITRKITSTET 4387
            V E+ V++ K  +KP++  P+  E  V   EV      + + E  VG  E+ +++ +  T
Sbjct: 1012 VNEKPVEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVG--EVPQEVLAPVT 1069

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
             E+    +T    +E      + P     +QP    E ++A+   +  G P P ++W++E
Sbjct: 1070 VEV---VETAPITLEDMKPTGEAPKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKE 1126

Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
               + +    ++      + L I     ED  ++  VA+N  G A  SA L +       
Sbjct: 1127 KAKVVDVRRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHINP----- 1181

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567
               +V P F    + + VT   + + + + TG    +V W     K++   R +++ E  
Sbjct: 1182 ---VVKPDFKTKLKPMEVTEESVAKFEVRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQD 1238

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
             + L+I +   +D+G Y+C   N AG A   A+  V     K+K         AP  + +
Sbjct: 1239 RHELIISDVKVKDAGTYKCTLANQAGTAYSRADLKV-----KEKD-------CAPEFVGD 1286

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
                 +V +G+ I+   +I  KP P V+WYK  K ++      +    D Y  ++  A P
Sbjct: 1287 QAAPIVVRQGEDIDIGAQITAKPKPNVKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKP 1346

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITS 4746
            ED G YKC A N+ G+ T    ++V  P    + P+L   L+ + V  G+  +   +I+ 
Sbjct: 1347 EDTGMYKCEATNAVGKATRTFDVQVEVPKPRGSKPSLEAELKPVTVTAGEDTKLVCKISG 1406

Query: 4747 KIKPTIQWLREGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
            K +P I W+++    P  PD +++  ++G   VL       ED   +   A    G V T
Sbjct: 1407 KPQPKIDWMKDDK--PLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVST 1464

Query: 4805 SAKLVVKSK 4813
            SA+L+V  K
Sbjct: 1465 SAELLVNEK 1473



 Score =  165 bits (400), Expect = 1e-39
 Identities = 110/375 (29%), Positives = 175/375 (46%), Gaps = 24/375 (6%)

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            ++W +++ PI      +    +    LI++ V  +D  V+     N+ G+A C ANL+V 
Sbjct: 1671 VEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLIVN 1730

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            EK        V P       N+ V    L R + ++ G     V W     K+      K
Sbjct: 1731 EKA-------VKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYK 1783

Query: 4562 ILEEDG--TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +LE+ G  T+TL++ ++   DSG Y+CVA+N AG+A   A   V            T   
Sbjct: 1784 MLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEV------------TGRP 1831

Query: 4620 NAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
             AP  + + +KD + V  GQ +     I G P P V WYK DK ++ S+  ++    + Y
Sbjct: 1832 CAPTFVEDEVKDAVYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMY 1891

Query: 4679 TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
             L I +A   D G Y+CVA N+ G V+    ++V    +A     ++ LR + V+EG   
Sbjct: 1892 YLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGKAPRF--VSELRPVEVFEGNEV 1949

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                +++++ KPT +W R G+ +      Q   +G  + L   N   ED GT++C A   
Sbjct: 1950 SLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNV 2009

Query: 4799 AGQVETSAKLVVKSK 4813
             G   + AKL+VK K
Sbjct: 2010 FGSASSQAKLLVKKK 2024



 Score =  150 bits (364), Expect = 2e-35
 Identities = 120/495 (24%), Positives = 208/495 (42%), Gaps = 33/495 (6%)

Query: 4331 EVTEQRVQKKVTQKPRIPDPSESTVHGK-------EVHVAKQKQTQKEVVGDKEITRKIT 4383
            EVTE+ V K   +    P P      G           V  ++   + ++ D ++  K  
Sbjct: 1195 EVTEESVAKFEVRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKV--KDA 1252

Query: 4384 STETTEIEHKAQTQERVVEGPVKPSK--PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
             T    + ++A T     +  VK     P     +  P  V + E      +   +P P 
Sbjct: 1253 GTYKCTLANQAGTAYSRADLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPN 1312

Query: 4442 IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVE 4501
            +KWY++  P+++ P   I          +     ED+ ++   A N  G A  + ++ VE
Sbjct: 1313 VKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372

Query: 4502 EKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
              + +G      PS     + V VT+G+  +L  K++G     + W+K+ K ++PD R  
Sbjct: 1373 VPKPRGS----KPSLEAELKPVTVTAGEDTKLVCKISGKPQPKIDWMKDDKPLKPDKRVL 1428

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANA 4621
               +  T  L   +A  +D  +Y+ VA N  G     AE +V+                A
Sbjct: 1429 PTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVN-------------EKGA 1475

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE--YT 4679
             P+I +PL+D  V  G+   F+ ++ G P P V+W+KG+ +++    F +   A E  + 
Sbjct: 1476 APKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQ 1535

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD--IVVYEGQP 4737
            L I +A PED G YKCV +N  G     AKL+V   + A         ++  I V E Q 
Sbjct: 1536 LVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQE 1595

Query: 4738 AQFKTQITSKIKPT-IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
                 ++  K  P  + W ++   +      ++  EG    L + +   +D G + C +T
Sbjct: 1596 VDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCEST 1655

Query: 4797 TAAGQVETSAKLVVK 4811
            T  G   ++  ++VK
Sbjct: 1656 TKLGTTISTFLIIVK 1670



 Score =  149 bits (360), Expect = 7e-35
 Identities = 94/316 (29%), Positives = 152/316 (48%), Gaps = 22/316 (6%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FTKK++P  V E ++AR +V   G P P ++W+     + ++  ++         LII
Sbjct: 726  PDFTKKLKPVEVEEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLII 785

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL---TAQNVNVTS 4527
            +    +D   +  VA N+ G   C  +L V EK       + PP  T    T + V +  
Sbjct: 786  KTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK-------MFPPEITRPERTEKIVLLEK 838

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
             +LV ++  + G    DV W K+GK ++   R  I     TYTL I    P+D+G Y C 
Sbjct: 839  EELV-INVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCE 897

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N  G +    +  V + A+K  PK +       P ++  L+ + ++EG+  +  CK+ 
Sbjct: 898  AQNKMGTSSTTID--VQIEASK--PKGEA------PSLVSELQPQEISEGEDAKLECKVS 947

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G+P PT++W+K D+ +      +        TL I +A  +DEGDYKCVA N  G  +  
Sbjct: 948  GEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSAT 1007

Query: 4708 AKLKVTQ-PDQADNLP 4722
             +L V + P + +  P
Sbjct: 1008 TELLVNEKPVEEEKQP 1023



 Score =  145 bits (351), Expect = 9e-34
 Identities = 107/408 (26%), Positives = 173/408 (42%), Gaps = 24/408 (5%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            K P F  +++P  VFE  +     +   E  P  +W R   P++     Q       S L
Sbjct: 1930 KAPRFVSELRPVEVFEGNEVSLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTL 1989

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
                  +ED   ++ +A+N  G+A   A L+V++K      G  P    +         G
Sbjct: 1990 KFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK------GNRPQPIGMIRDIEGYEGG 2043

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG--TYTLLILEAYPQDSGKYEC 4586
            Q  R D   TG   ++  WL   +++    + KI E  G   Y+L++ +   +D G+Y C
Sbjct: 2044 Q-ARFDVHFTGNPKVE--WLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTC 2100

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE-GQAIEFSCK 4645
            VA N +G+A   A   V     KDK         AP  + +   + I  E G+ +     
Sbjct: 2101 VASNESGDATLHANLNV-----KDK-------HIAPMFVEDDTGEPITVEAGKELNVIMN 2148

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            I G P P V WYK    ++ +    +S   D Y L + +A P+D G Y+C A N  G  +
Sbjct: 2149 IRGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTAS 2208

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
                +KV +         +T L  + + EG       +++ K KPTI W R+   +    
Sbjct: 2209 RTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHTDN 2268

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                 +EG+ + L +      D G + C AT + G   +SA++ +K K
Sbjct: 2269 RVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRK 2316



 Score =  142 bits (343), Expect = 8e-33
 Identities = 103/395 (26%), Positives = 171/395 (43%), Gaps = 18/395 (4%)

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477
            +P  V   ++    +   G P P + WY++   ++ +    I +      L + +   +D
Sbjct: 2133 EPITVEAGKELNVIMNIRGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDD 2192

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            + ++   A+N+ GTA  +  + VEE +  GRG    PSF      V +  G    L  +V
Sbjct: 2193 AGIYRCEAKNKLGTASRTVMVKVEELK--GRG---VPSFITGLFPVQIKEGDKYTLVCRV 2247

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
            +G     + W ++   V  D R     E     L + E    D+G Y+C A NS G    
Sbjct: 2248 SGKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSS 2307

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             AE  +             K  +A P  +  LK+    E   +    KI G P PTV++Y
Sbjct: 2308 SAEVTI-------------KRKDAIPTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFY 2354

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            K   LI  S+  ++    D  +L I+   PED G YKCV  N  G  T  A ++V + + 
Sbjct: 2355 KDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREH 2414

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777
            A         + +   EG        I  K +PT+ W+++G +I  +    +   G +  
Sbjct: 2415 APRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYS 2474

Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            L+I    +ED+G +TC+A ++ G+   S  L V++
Sbjct: 2475 LVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEA 2509



 Score =  140 bits (340), Expect = 2e-32
 Identities = 120/413 (29%), Positives = 172/413 (41%), Gaps = 38/413 (9%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR------ENFPIKNSPDFQIHTFST 4464
            P+  K +   +V E    RFEV+  G P P + WY       E    K   D   HTF+ 
Sbjct: 1736 PVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFT- 1794

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQN 4522
               LI+      DS V+  VA N  G A   A L V        G    P+F        
Sbjct: 1795 ---LIVNDSQRHDSGVYKCVAVNEAGKAISQATLEV-------TGRPCAPTFVEDEVKDA 1844

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            V V  GQ V L   + G    DV W K+ K++Q     KI+ +   Y L+I +A   DSG
Sbjct: 1845 VYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSG 1904

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y CVA N+ G          S+  T D    + +     P  +  L+   V EG  +  
Sbjct: 1905 IYRCVAKNTHG----------SVSRTFD---VRVEVDGKAPRFVSELRPVEVFEGNEVSL 1951

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
             CK+  +  PT +W +    ++     Q S      TL+   A  ED+G Y C+A N  G
Sbjct: 1952 VCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFG 2011

Query: 4703 RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
              +  AKL V +  + +    +  +RDI  YEG  A+F    T    P ++WL     I 
Sbjct: 2012 SASSQAKLLVKK--KGNRPQPIGMIRDIEGYEGGQARFDVHFTG--NPKVEWLHGEEQII 2067

Query: 4763 ETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                +++       +  L++G+   ED G +TC A+  +G     A L VK K
Sbjct: 2068 HGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120



 Score =  140 bits (340), Expect = 2e-32
 Identities = 107/431 (24%), Positives = 186/431 (43%), Gaps = 24/431 (5%)

Query: 4389 EIEHKAQTQERVVEGPVKPSKP---PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445
            E ++K  T  R V   V+  K    P F   + P ++ E ++        G+P P I W+
Sbjct: 2199 EAKNKLGTASRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVSGKPKPTITWF 2258

Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRR 4505
            R+N P+            + S L ++++ + D+ ++   A N  G+   SA + ++ K  
Sbjct: 2259 RDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKD- 2317

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
                    P+F +  +         +RLD K+ G     V + K+   +    R+KILE+
Sbjct: 2318 ------AIPTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILED 2371

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
                +L+I    P+D+G Y+CV  N  G     +E V+ +   +  P+            
Sbjct: 2372 GDRCSLIITNLRPEDAGTYKCVITNLLGVET--SEAVIRVQEREHAPRFDGT-------- 2421

Query: 4626 IEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
               L   + A EG  +  +  I GKP PTV W K   +I  S    + +  + Y+L I +
Sbjct: 2422 --DLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIK 2479

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQ 4743
               ED G+Y C A +S G+ + +  LKV  P   +  P+ L+ L  + V EG   +   +
Sbjct: 2480 VTKEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGFEFKLIFK 2539

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            + +     I+W ++G       + +   +G N  L   N   +D G + C  T   G+  
Sbjct: 2540 VVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESS 2599

Query: 4804 TSAKLVVKSKT 4814
            +SA + +  KT
Sbjct: 2600 SSADISITQKT 2610



 Score =  134 bits (323), Expect = 2e-30
 Identities = 97/356 (27%), Positives = 151/356 (42%), Gaps = 21/356 (5%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G+P P + W ++   I +S    +        L+I +V  EDS  +   A +  G A  S
Sbjct: 2443 GKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQS 2502

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
             +L VE  + +      PPSF      + V  G   +L  KV  TK   + W K+G+   
Sbjct: 2503 FDLKVEAPKVKEE----PPSFLSELPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFT 2558

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P   ++   +    TL    A  +D+G+Y+C+  N  GE+   A+  ++    K      
Sbjct: 2559 PGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQKTRK------ 2612

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675
                   PE I PLK     EG    F  ++   PLP V WY G   I     +++ ++ 
Sbjct: 2613 -------PEAIAPLKSIESVEGGQARFDVEMSAFPLPKVDWYHGGTKITHGGRYKIIQST 2665

Query: 4676 DE----YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
            D     YTL I      D G YKC+A N  G  T+ + LKV +P  A           +V
Sbjct: 2666 DGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVKEPFIAPEFEGKDITAPMV 2725

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
              +GQ  +   +I S+ KP I W ++G  +  +    +   G+   L+I    +ED
Sbjct: 2726 YKDGQDIKVSFKIKSRPKPIIAWYKDGKALTSSKRVTLTSRGDTYELIIKKATKED 2781



 Score =  128 bits (309), Expect = 1e-28
 Identities = 120/520 (23%), Positives = 212/520 (40%), Gaps = 52/520 (10%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G  AK   K+ G+PTP V W ++KA +V+  +  M Y +     +L I    P D+G Y
Sbjct: 1103 EGDEAKLVCKITGSPTPTVEWFKEKAKVVDVRRTKMEYTDDVA--TLTIPTTRPEDKGMY 1160

Query: 145  TCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR 202
             C A+N +GEA  S  ++I P                    E+V      + G+      
Sbjct: 1161 KCVAKNDFGEASTSATLHINP---VVKPDFKTKLKPMEVTEESVAKFEVRSTGFP----- 1212

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFEYR---LLREVSFRESITKR--YVGESDVQIS-TEI 256
            Q +   +   T    +  F+V + + R   ++ +V  +++ T +     ++    S  ++
Sbjct: 1213 QPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQAGTAYSRADL 1272

Query: 257  DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
                   +P  +  +     +++G D     Q++  P+P V W+K+G+ L +  +  I  
Sbjct: 1273 KVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVKWYKDGKPLRDGPRTTIRA 1332

Query: 317  THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
              +    +V + +  D+G Y   A N  G    +  + VE P                + 
Sbjct: 1333 RDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVEVP----------------KP 1376

Query: 377  RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            R ++  +E   K +            VT G+ T+  C+++G+P P++ W  +D+ ++ D 
Sbjct: 1377 RGSKPSLEAELKPVT-----------VTAGEDTKLVCKISGKPQPKIDWMKDDKPLKPD- 1424

Query: 437  NHKILVNESGNHALMITN-VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
              ++L    G   ++  +   L D      VA+N+ G  +    L V EK    APK  +
Sbjct: 1425 -KRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEKG--AAPKIEK 1481

Query: 496  RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG--GASTLDIPRA 553
                + V  G+    N +  GTPTP + W K    +       I  D   G   L I  A
Sbjct: 1482 PLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDA 1541

Query: 554  KASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRL 593
            K  D+  Y+C   N  G T T+A+L            K+L
Sbjct: 1542 KPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKL 1581



 Score =  128 bits (308), Expect = 1e-28
 Identities = 99/405 (24%), Positives = 170/405 (41%), Gaps = 21/405 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F   ++     E    R +V+  G P P +++Y++   I +S   +I     +  LII
Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLII 2379

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
              +  ED+  +  V  N  G     A + V+E+    R        T   Q+V    G  
Sbjct: 2380 TNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREHAPRF-----DGTDLGQSVTAQEGFE 2434

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            +     + G     V W+K+G  +       + +   +Y+L+I++   +DSG Y C A++
Sbjct: 2435 LNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVS 2494

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
            S G+A    +  V  P  K++P          P  +  L    V EG   +   K+V   
Sbjct: 2495 SLGKASQSFDLKVEAPKVKEEP----------PSFLSELPPLQVREGFEFKLIFKVVTTK 2544

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
               ++W K  +   P    + S      TL    A  +D G Y+C+  N  G  + +A +
Sbjct: 2545 DSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADI 2604

Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMI 4770
             +TQ  +     A+ PL+ I   EG  A+F  ++++   P + W   G  I     +++I
Sbjct: 2605 SITQKTRKPE--AIAPLKSIESVEGGQARFDVEMSAFPLPKVDWYHGGTKITHGGRYKII 2662

Query: 4771 H--EGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               +G+  V  L+I +    D+GT+ C AT   G     + L VK
Sbjct: 2663 QSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVK 2707



 Score =  119 bits (287), Expect = 5e-26
 Identities = 81/310 (26%), Positives = 143/310 (46%), Gaps = 37/310 (11%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN--HTTL 323
           P+  +K +   ++EG       ++ G P P V W  +G+++   + H I TT +    TL
Sbjct: 27  PEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKV--QDDHRIKTTFDGERCTL 84

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI 383
           ++  +++ D G Y         C+ T+                      +  Q      +
Sbjct: 85  KIMPSERDDEGEYK--------CVATN----------------------EVGQATITTEV 114

Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            + E    P+F +  Q   V EG   RFD R+ G+P P+V WF N  +I ++   +I ++
Sbjct: 115 LVKETLRKPEFKQKMQPLQVLEGDEVRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEI-ID 173

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
           E   ++L+I +  LSD+    C+A +++G++   C + +  KE+  AP+     + +N+ 
Sbjct: 174 EEDLYSLIIDDTRLSDADTYKCIATSEAGKST--CIVELSVKEKTSAPEVFGDTAPINIT 231

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
           EG+ + L+ R  G P P I W KD  PI     L   T      L +  AK  D+  Y+C
Sbjct: 232 EGDELDLSVRVRGKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKC 291

Query: 564 TAQNVAGSTA 573
           TA++  G+ +
Sbjct: 292 TAKSEHGTAS 301



 Score =  119 bits (286), Expect = 7e-26
 Identities = 83/314 (26%), Positives = 141/314 (44%), Gaps = 32/314 (10%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+  QK +  ++ EG + +F V++ G P P+V WFKN  ++ N  + EII   +  +L +
Sbjct: 123 PEFKQKMQPLQVLEGDEVRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLII 182

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
            +T+ SD+  Y         CI TS             +  +S  I +         + +
Sbjct: 183 DDTRLSDADTYK--------CIATS-------------EAGKSTCIVE---------LSV 212

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            EK  AP+        ++TEG       RV G+P PE+ W  +D+ I+   +      + 
Sbjct: 213 KEKTSAPEVFGDTAPINITEGDELDLSVRVRGKPKPEIKWTKDDKPIKKT-DRLTTTTKD 271

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVRE 504
               L++++    DSG   C A+++ G  + +  +NV + K + VAPKF +   TL + E
Sbjct: 272 DECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIME 331

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            E   L     G P P   W K   P+     ++I  D  +  L++   +  D A Y+  
Sbjct: 332 KETARLECTVTGEPAPTTEWLKGDQPLKETQRIKIERDKDSVVLEVRHVELDDEALYKVV 391

Query: 565 AQNVAGSTATRARL 578
           A+N +G   + A L
Sbjct: 392 AKNESGVATSEAEL 405



 Score =  113 bits (273), Expect = 2e-24
 Identities = 112/516 (21%), Positives = 193/516 (37%), Gaps = 29/516 (5%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F +  +     +   A+ E  + G P P   W +   PL E  +  +  ++ +  V L
Sbjct: 318 PKFTKPLETLEIMEKETARLECTVTGEPAPTTEWLKGDQPLKETQRIKIERDKDS--VVL 375

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAI--CSVYIQPEGXXXXXXXXXXXXXYRHVSET-VEH 188
            ++ +   DE  Y   A+N+ G A     + +                      E  ++ 
Sbjct: 376 EVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLEGDEIRLDA 435

Query: 189 KAYGTQGYTTEQSRQTQKVAYTNG---TDHSSTDDFKVDTFEYRLLREVSFRESITKRYV 245
           +  G    T +  +  QKVA        D    D F +     + L    +    T    
Sbjct: 436 RVGGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATND-T 494

Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
           G++  +   +I+  L  V+P    ++     L E  D   ++ ++G P+P V W K+ + 
Sbjct: 495 GKATAEAEIQIEELL--VAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKP 552

Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
           L   ++  I    +   + +     +DSG Y   A+N  G             T +++ +
Sbjct: 553 LTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGV-----------NTRTFIVN 601

Query: 366 QRSQYITDTQQRETEER-IEISEKAL--APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
               ++    Q     R I +++K    AP+  +  Q+ +  EG      C+ TG P P 
Sbjct: 602 VEVLFVAGISQVIGSIRFIVLAKKPAGEAPEITESLQEMEELEGNPVTLTCKFTGTPAPV 661

Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             WF     +RD   +KI   ++    L I    L D+     V RN  G    + R+ +
Sbjct: 662 AEWFKASTPVRDGRRYKITTTDN-TTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRI 720

Query: 483 IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542
                +V P F ++   + V EG+   L+ R VGTPTP + W      +          +
Sbjct: 721 ---TALVRPDFTKKLKPVEVEEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEE 777

Query: 543 GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           G + TL I      D   Y+C A N  G    R  L
Sbjct: 778 GDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDL 813



 Score =  113 bits (271), Expect = 4e-24
 Identities = 77/262 (29%), Positives = 114/262 (43%), Gaps = 15/262 (5%)

Query: 4543 IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
            + V WLK+ K +  D   K    +G  TL++     QD G Y+C   N  G A C A  +
Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG-DK 4661
            V+  A K             P I++PL +  V E     F  +I G P P V WY G  K
Sbjct: 1729 VNEKAVK-------------PVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTK 1775

Query: 4662 LIKPSKYFQMSRTADE-YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            LI+ + Y  +  + +  +TL ++++   D G YKCVA N AG+    A L+VT    A  
Sbjct: 1776 LIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPT 1835

Query: 4721 LPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLI 4780
                     + V  GQ       I     P + W ++   + E+   ++I +GN   L+I
Sbjct: 1836 FVEDEVKDAVYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLII 1895

Query: 4781 GNTYEEDTGTFTCRATTAAGQV 4802
                  D+G + C A    G V
Sbjct: 1896 YKASLNDSGIYRCVAKNTHGSV 1917



 Score =  112 bits (270), Expect = 6e-24
 Identities = 117/521 (22%), Positives = 205/521 (39%), Gaps = 45/521 (8%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F++  +N    +G   + + ++ G P P V W +    + E  ++ +  +E+    SL
Sbjct: 414 PFFKKTPQNVTVLEGDEIRLDARVGGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSL 473

Query: 132 LIKQIGP-----------GDEGEYTCTARNQYGEAICSV-YIQPEGXXXXXXXXXXXXXY 179
           +I    P            D G+ T  A  Q  E + +  + + E               
Sbjct: 474 IIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLE 533

Query: 180 RHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV---DTFEYRLLREVSF 236
            HV+   + + + T+    +   +  ++   +  D    D   V   D+  Y+   E   
Sbjct: 534 LHVTGKPKPEVHWTKD--NKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKC--EAKN 589

Query: 237 RESI-TKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRP 295
           +  + T+ ++   +V     I + +G +    +A+KP     +     Q   +L GNP  
Sbjct: 590 KAGVNTRTFIVNVEVLFVAGISQVIGSIRFIVLAKKPAGEAPEITESLQEMEELEGNPVT 649

Query: 296 RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
               F               T          +T   D   Y +   + N   +T     +
Sbjct: 650 LTCKFTG-------------TPAPVAEWFKASTPVRDGRRYKITTTD-NTTTLTIKETRL 695

Query: 356 ESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRV 415
           +  TE  V  +      D    ++E R+ I+   + P F K  +  +V EG+  R D RV
Sbjct: 696 DDNTEYQVVIRN-----DIGSVKSETRVRITA-LVRPDFTKKLKPVEVEEGQEARLDVRV 749

Query: 416 TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETA 475
            G P P V WF    ++ D   ++  + E  ++ L+I      D     CVA N+ G+  
Sbjct: 750 VGTPTPNVEWFCGTTKLTDTDRYE-FIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVT 808

Query: 476 FQCRLNVIEKEQVVAPKFV--ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
             CR ++   E++  P+    ER   + + E E +V+N   +G P P + W KDG PI  
Sbjct: 809 --CRGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQ 866

Query: 534 NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
           +  L I   G   TL+I   +  DA  Y C AQN  G+++T
Sbjct: 867 SSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSST 907



 Score =  112 bits (270), Expect = 6e-24
 Identities = 118/490 (24%), Positives = 191/490 (38%), Gaps = 44/490 (8%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            +RGNP P V+W +  + L +  +  M  + +     L + +  P D G Y C A+N+ G 
Sbjct: 2149 IRGNPRPDVNWYKDGSFLQQTGR--MGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGT 2206

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYR-HVSE----TVEHKAYGTQGYTTEQSRQTQKVAY 209
            A  +V ++ E              +   + E    T+  +  G    T    R    V  
Sbjct: 2207 ASRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHT 2266

Query: 210  TNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIA 269
             N    S          +   L +    +       G +       I R     + P   
Sbjct: 2267 DNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRK---DAIPTFV 2323

Query: 270  QKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQ 329
               + ++  E +D +  V++ G PRP V ++K+   +++S +H+I+   +  +L + N +
Sbjct: 2324 VGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLR 2383

Query: 330  KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKA 389
              D+G Y         C++T+  L VE+                     +E  I + E+ 
Sbjct: 2384 PEDAGTYK--------CVITN-LLGVET---------------------SEAVIRVQERE 2413

Query: 390  LAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447
             AP+F      + VT  EG        + G+P P VTW + D  +    N   L     +
Sbjct: 2414 HAPRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTW-MKDGNVISSSNGVSLRQRGES 2472

Query: 448  HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-IEKEQVVAPKFVERFSTLNVREGE 506
            ++L+I  VT  DSG  TC A +  G+ +    L V   K +   P F+     L VREG 
Sbjct: 2473 YSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGF 2532

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
               L  + V T   +I W+KDG    P        DG   TL    A   DA  YQC   
Sbjct: 2533 EFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVT 2592

Query: 567  NVAGSTATRA 576
            N  G +++ A
Sbjct: 2593 NKFGESSSSA 2602



 Score =  111 bits (266), Expect = 2e-23
 Identities = 85/318 (26%), Positives = 150/318 (47%), Gaps = 39/318 (12%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I +   N +++E +  +F+VQ++GNP+PRV W+    +LI    ++++          
Sbjct: 1736 PVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKML---------- 1785

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
                  DSG++T         ++ +     +S     V       + +  +  ++  +E+
Sbjct: 1786 -----EDSGNHTFT-------LIVNDSQRHDSGVYKCVA------VNEAGKAISQATLEV 1827

Query: 386  SEKALAPQFVK--VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
            + +  AP FV+  V     V  G+       + G P P+V W+ +D+++++    KI+  
Sbjct: 1828 TGRPCAPTFVEDEVKDAVYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKII-- 1885

Query: 444  ESGN-HALMITNVTLSDSGVVTCVARNKSGETA--FQCRLNVIEKEQVVAPKFVERFSTL 500
              GN + L+I   +L+DSG+  CVA+N  G  +  F  R+ V  K    AP+FV     +
Sbjct: 1886 PKGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGK----APRFVSELRPV 1941

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             V EG  V L  +      P   W ++G P+  +  ++   DG  STL    AK  D   
Sbjct: 1942 EVFEGNEVSLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGT 2001

Query: 561  YQCTAQNVAGSTATRARL 578
            Y C A+NV GS +++A+L
Sbjct: 2002 YSCLAKNVFGSASSQAKL 2019



 Score =  110 bits (265), Expect = 2e-23
 Identities = 97/389 (24%), Positives = 160/389 (41%), Gaps = 26/389 (6%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
            ++    +  +G P P + WY+++  ++ S   +I        LII +  + DS ++  VA
Sbjct: 1851 QEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVA 1910

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
            +N  G+   + ++ VE     G+     P F    + V V  G  V L  K++       
Sbjct: 1911 KNTHGSVSRTFDVRVEV---DGKA----PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF 1963

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTY-TLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
             W +NG  V+ D R +    DG Y TL  L A  +D G Y C+A N  G A   A+ +V 
Sbjct: 1964 EWSRNGSPVRLDNRVQ-ASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVK 2022

Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
                        K  N  P+ I  ++D    EG    F     G   P V+W  G++ I 
Sbjct: 2023 ------------KKGNR-PQPIGMIRDIEGYEGGQARFDVHFTGN--PKVEWLHGEEQII 2067

Query: 4665 PSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
              + +++S    E  Y+L + +   ED G Y CVA N +G  T+ A L V     A    
Sbjct: 2068 HGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDKHIAPMFV 2127

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782
                   I V  G+       I    +P + W ++G+ + +T    +    ++  L +  
Sbjct: 2128 EDDTGEPITVEAGKELNVIMNIRGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFK 2187

Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               +D G + C A    G    +  + V+
Sbjct: 2188 AVPDDAGIYRCEAKNKLGTASRTVMVKVE 2216



 Score =  106 bits (255), Expect = 4e-22
 Identities = 119/524 (22%), Positives = 214/524 (40%), Gaps = 52/524 (9%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           P + + P F +  +     +G     + +++G PTP V W      + + ++    ++ +
Sbjct: 21  PDKGTIPEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKVQDDHRIKTTFDGE 80

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET 185
              + ++  +    DEGEY C A N+ G+A  +  +  +               + V E 
Sbjct: 81  RCTLKIMPSE--RDDEGEYKCVATNEVGQATITTEVLVKETLRKPEFKQKMQPLQ-VLEG 137

Query: 186 VEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFE--YRLL-REVSFRESIT 241
            E      +       + T KV  + N T   +   F++   E  Y L+  +    ++ T
Sbjct: 138 DE-----VRFDVRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADT 192

Query: 242 KRYVGESDVQISTEI-DRSLGP-VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
            + +  S+   ST I + S+    S P++        + EG +    V++ G P+P + W
Sbjct: 193 YKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINITEGDELDLSVRVRGKPKPEIKW 252

Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
            K+ + +    K + +TT          T K D             C++    L+   P 
Sbjct: 253 TKDDKPI---KKTDRLTT----------TTKDDE------------CVLV---LSDAKPE 284

Query: 360 ES--YVQDQRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVT 416
           +S  Y    +S++   T  +E +  +E ++ K +AP+F K  +  ++ E +  R +C VT
Sbjct: 285 DSGRYKCTAKSEH--GTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKETARLECTVT 342

Query: 417 GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
           G P P   W   D+ +++    KI   +  +  L + +V L D  +   VA+N+SG    
Sbjct: 343 GEPAPTTEWLKGDQPLKETQRIKI-ERDKDSVVLEVRHVELDDEALYKVVAKNESGVATS 401

Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536
           +  L V   E    P F +    + V EG+ + L+AR  G P P + W K    +     
Sbjct: 402 EAELLV--NEATEKPFFKKTPQNVTVLEGDEIRLDARVGGKPEPTVDWFKGDQKVAEEGR 459

Query: 537 LRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I  D  G   +L I  AK  D+  Y C A N  G     A +
Sbjct: 460 FLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEI 503



 Score =  106 bits (255), Expect = 4e-22
 Identities = 141/651 (21%), Positives = 251/651 (38%), Gaps = 63/651 (9%)

Query: 231  LREVSFRESITKRYVGESDV-QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL 289
            ++E    ++   + V  +D+  + +E    +  +  P   +K +  +++EG +A+  V++
Sbjct: 690  IKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEVEEGQEARLDVRV 749

Query: 290  SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
             G P P V WF    +L +             T R    ++ DS  YTL+ +        
Sbjct: 750  VGTPTPNVEWFCGTTKLTD-------------TDRYEFIEEGDS--YTLIIKT------- 787

Query: 350  SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVT--EGK 407
                 V    ++Y     +Q    T + +    ++++EK   P+  +  +   +   E +
Sbjct: 788  ----TVRDDDDTYKCVASNQVGKVTCRGD----LKVTEKMFPPEITRPERTEKIVLLEKE 839

Query: 408  MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCV 466
                +  + G P P+V WF + + IR   + ++ +   G+ + L I      D+G  TC 
Sbjct: 840  ELVINVTILGNPRPDVKWFKDGKPIRQ--SSRLNIRPRGDTYTLNIHTTEPEDAGSYTCE 897

Query: 467  ARNKSGETAFQCRLNV-IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
            A+NK G ++    + +   K +  AP  V       + EGE   L  +  G P P I W 
Sbjct: 898  AQNKMGTSSTTIDVQIEASKPKGEAPSLVSELQPQEISEGEDAKLECKVSGEPQPTIEWF 957

Query: 526  KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXX 585
            KD  P+  +  +R   DG  STL I  A   D   Y+C A N  GST+    L       
Sbjct: 958  KDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPV 1017

Query: 586  XXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYI-PPGEEDRVYPPPQFIVPLK 644
                Q     P   KV             +   E   P    P  E  V   PQ ++   
Sbjct: 1018 EEEKQ-----PEKPKVEKPEVEEPE----VEKPEVEEPVSGKPEVETPVGEVPQEVLAPV 1068

Query: 645  SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704
            +V  +E   I  E  ++P G+    ++ L+  +++E               +  ++ +  
Sbjct: 1069 TVEVVETAPITLED-MKPTGEAPKVVDALQPLEALEGDEAKL---------VCKITGSPT 1118

Query: 705  DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPET--LQYIQQLEDYSKYQHQESI 762
             + E+         V  TK + +    AT+   +  PE   +       D+ +     ++
Sbjct: 1119 PTVEWFKEKAKVVDVRRTK-MEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATL 1177

Query: 763  EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822
                  +P F   L+ + E+ E   A FE + T    P   VEW+     I  S R   +
Sbjct: 1178 HINPVVKPDFKTKLKPM-EVTEESVAKFEVRSTGFPQP--EVEWFLGSTKIEDSGRFRVV 1234

Query: 823  FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLG 873
                   L I  ++ +DAG+Y     N+ G A S A ++V  +      +G
Sbjct: 1235 SEQDRHELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKDCAPEFVG 1285



 Score =  104 bits (250), Expect = 2e-21
 Identities = 126/517 (24%), Positives = 213/517 (41%), Gaps = 68/517 (13%)

Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            +IE  +PK   P  V+EL+    + EG+ A  EC+V    +P   IE++ + + + +  R
Sbjct: 912  QIEASKPKGEAPSLVSELQ-PQEISEGEDAKLECKVSG--EPQPTIEWFKDDEPVTTDNR 968

Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350
                +D    +L I+    +D G+Y   A N LG  ++   + V  K   + E ++PE  
Sbjct: 969  VRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKP--VEEEKQPEK- 1025

Query: 2351 EKIRELESAEP-FKRPEIPEPVTR----QRPVFTQPLQNID--NIQEGQTAHFDCR-LIP 2402
             K+ + E  EP  ++PE+ EPV+     + PV   P + +    ++  +TA      + P
Sbjct: 1026 PKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKP 1085

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXX 2462
             G+    V+  +  + +E           G  + T+   +++ + V + R          
Sbjct: 1086 TGEAPKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVVDVRRTK-------- 1137

Query: 2463 XXXXXXXXXXXIQLETQHPE--GMKKIQKLEQPHERRSEEP--DREFEKPIFTQVLTGPS 2518
                       + + T  PE  GM K        E  +          KP F   L  P 
Sbjct: 1138 --MEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHINPVVKPDFKTKLK-PM 1194

Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578
            E+ E   A +E R    G P    EW++   +++   RFR   +     L I+ V   DA
Sbjct: 1195 EVTEESVAKFEVR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDA 1252

Query: 2579 GLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGV 2638
            G Y C   N+AG                        ++ +  LK    +  PE FV  G 
Sbjct: 1253 GTYKCTLANQAGT-----------------------AYSRADLKVKEKDCAPE-FV--GD 1286

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            Q API            +G+ + + AQ+  +  PN+K  W+K+G  L  G R        
Sbjct: 1287 QAAPIVVR---------QGEDIDIGAQITAKPKPNVK--WYKDGKPLRDGPRTTIRARDD 1335

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L    + S + +D+G+Y C+ATN +G+A  T  +++E
Sbjct: 1336 LYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372



 Score =  103 bits (246), Expect = 5e-21
 Identities = 99/430 (23%), Positives = 171/430 (39%), Gaps = 40/430 (9%)

Query: 61   ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            + A +P   +P I E + +     +G       K  G P PV  W +   P+ +  +Y +
Sbjct: 621  VLAKKPAGEAPEITESL-QEMEELEGNPVTLTCKFTGTPAPVAEWFKASTPVRDGRRYKI 679

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYR 180
               + T   +L IK+    D  EY    RN  G       ++                  
Sbjct: 680  TTTDNT--TTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEV 737

Query: 181  HVSE--TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRE 238
               +   ++ +  GT     E    T K+  T+  +     D      +  +  +    +
Sbjct: 738  EEGQEARLDVRVVGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYK 797

Query: 239  SITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPR 296
             +    VG+   +   ++   +    PP+I +  R  K  L E  +    V + GNPRP 
Sbjct: 798  CVASNQVGKVTCRGDLKVTEKM---FPPEITRPERTEKIVLLEKEELVINVTILGNPRPD 854

Query: 297  VTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
            V WFK+G+ +  S++  I    +  TL +  T+  D+G YT  A+N  G   T+  + +E
Sbjct: 855  VKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIE 914

Query: 357  SPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT 416
            +                  + + E    +SE  L PQ        +++EG+  + +C+V+
Sbjct: 915  A-----------------SKPKGEAPSLVSE--LQPQ--------EISEGEDAKLECKVS 947

Query: 417  GRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVTCVARNKSGETA 475
            G P P + WF +D  +  D  +++  +  G    L I + TL D G   CVA N+ G T+
Sbjct: 948  GEPQPTIEWFKDDEPVTTD--NRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTS 1005

Query: 476  FQCRLNVIEK 485
                L V EK
Sbjct: 1006 ATTELLVNEK 1015



 Score =  103 bits (246), Expect = 5e-21
 Identities = 64/193 (33%), Positives = 99/193 (51%), Gaps = 7/193 (3%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            ++EKA+ P  VK   +  V E  +TRF+ ++ G P P V W+    ++ +   +K+L  +
Sbjct: 1729 VNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKML-ED 1787

Query: 445  SGNH--ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER--FSTL 500
            SGNH   L++ +    DSGV  CVA N++G+   Q  L V  +    AP FVE      +
Sbjct: 1788 SGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRP--CAPTFVEDEVKDAV 1845

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             VR G+ V L     G PTP + W KD   +  +  ++I   G    L I +A  +D+  
Sbjct: 1846 YVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGI 1905

Query: 561  YQCTAQNVAGSTA 573
            Y+C A+N  GS +
Sbjct: 1906 YRCVAKNTHGSVS 1918



 Score =  102 bits (244), Expect = 8e-21
 Identities = 84/328 (25%), Positives = 142/328 (43%), Gaps = 38/328 (11%)

Query: 249  DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
            DVQ+  E+ +  G  S P +  + +   +  G D +   ++SG P+P++ W K+ + L  
Sbjct: 1368 DVQV--EVPKPRG--SKPSLEAELKPVTVTAGEDTKLVCKISGKPQPKIDWMKDDKPLKP 1423

Query: 309  SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
              +  ++ T++  T                       C++T     +E   E  V  +  
Sbjct: 1424 DKR--VLPTYDGET-----------------------CVLTFHKAVLEDEAEYKVVAKN- 1457

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
                +     T   + ++EK  AP+  K  QD  V  GK   F+ +V+G P PEV WF  
Sbjct: 1458 ----ELGSVSTSAELLVNEKGAAPKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKG 1513

Query: 429  DRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV--IEK 485
            +  + D     I+ + + G   L+I +    DSGV  CV  N  GET  + +L V  +E 
Sbjct: 1514 ESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEV 1573

Query: 486  EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGG 544
                  K  E+   + V E + V ++ +  G   P ++ W KD  P+  N   +IH++G 
Sbjct: 1574 APKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGR 1633

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAGST 572
               L +  A   DA  Y+C +    G+T
Sbjct: 1634 MYYLTLTDASLDDAGHYRCESTTKLGTT 1661



 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 54/198 (27%), Positives = 90/198 (45%), Gaps = 3/198 (1%)

Query: 383  IEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            + + +K +AP FV+      +T   GK       + G P P+V W+  D           
Sbjct: 2115 LNVKDKHIAPMFVEDDTGEPITVEAGKELNVIMNIRGNPRPDVNWY-KDGSFLQQTGRMG 2173

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
            + +   ++ L +      D+G+  C A+NK G  +    + V E +    P F+     +
Sbjct: 2174 ISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVEELKGRGVPSFITGLFPV 2233

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
             ++EG+   L  R  G P P ITW +D  P+  +  +    +G  S L++   K SDA  
Sbjct: 2234 QIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGL 2293

Query: 561  YQCTAQNVAGSTATRARL 578
            Y+CTA N  GST++ A +
Sbjct: 2294 YKCTATNSQGSTSSSAEV 2311



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 111/462 (24%), Positives = 179/462 (38%), Gaps = 31/462 (6%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +S L      EG++   EC V     PT  IEWF +++P+ +  R ++ +D    +L I 
Sbjct: 926  VSELQPQEISEGEDAKLECKVSGEPQPT--IEWFKDDEPVTTDNRVRADYDGKTSTLTIR 983

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAE----E 2892
                +D G Y C ATN  GS + +  L    +K +  + Q  + K     VE+ E    E
Sbjct: 984  DATLDDEGDYKCVATNELGSTSATTEL-LVNEKPVEEEKQPEKPKVEKPEVEEPEVEKPE 1042

Query: 2893 ARLAKGRRPSV--PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFN 2950
                   +P V  P  E P+ E + P+  E  +VE   + LE  ++P  +    ++    
Sbjct: 1043 VEEPVSGKPEVETPVGEVPQ-EVLAPVTVE--VVETAPITLE-DMKPTGEAPKVVDALQP 1098

Query: 2951 GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLI 3010
             + LE G   KL           V+ ++  + +   +          +   Y      L 
Sbjct: 1099 LEALE-GDEAKLVCKITGSPTPTVEWFKEKAKVVDVRR---------TKMEYTDDVATLT 1148

Query: 3011 ERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEA 3070
              T  P+  +G+ K     D            +    P+F T  K + +++E  +A +E 
Sbjct: 1149 IPTTRPED-KGMYKCVAKNDFGEASTSATLHINPVVKPDFKTKLKPM-EVTEESVAKFEV 1206

Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
                TG     +EWF     IE S R R V       L I   K  D+GTY C   N+ G
Sbjct: 1207 R--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQAG 1264

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
             A     L+   K K   P F         ++ G+       +     P++K  WY +G+
Sbjct: 1265 TAYSRADLKV--KEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVK--WYKDGK 1320

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            P+R   R    +        +   +  D+G Y C A N  G+
Sbjct: 1321 PLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGK 1362



 Score = 95.1 bits (226), Expect = 1e-18
 Identities = 120/514 (23%), Positives = 198/514 (38%), Gaps = 71/514 (13%)

Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367
            M  P+ +R     + V      L   +  +G+    V+WF +GKPI+   R       D 
Sbjct: 819  MFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDT 878

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
              L++ +  PED+G YTC+A N++G + T+         D+ +E+  P G          
Sbjct: 879  YTLNIHTTEPEDAGSYTCEAQNKMGTSSTTI--------DVQIEASKPKG---------- 920

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
               +   ++ E   ++P         + + EG+    ECK+    +    +EWFK+ +PV
Sbjct: 921  ---EAPSLVSE---LQP---------QEISEGEDAKLECKVSG--EPQPTIEWFKDDEPV 963

Query: 1488 TIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQ 1547
            T  +R R  +D     L I D   +D G Y C A N +G+   +  L             
Sbjct: 964  TTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPVEEEKQP 1023

Query: 1548 NEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDA 1607
             +  +E+ +V E   +      V+E  +  P   T +   E+ +   A     ++  +  
Sbjct: 1024 EKPKVEKPEVEEPEVEKPE---VEEPVSGKPEVETPVG--EVPQEVLAPVTVEVVETAPI 1078

Query: 1608 TLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT---- 1663
            TL+     + KP     +  +       AL  +  L  D     C+   +    V     
Sbjct: 1079 TLE-----DMKPTGEAPKVVD-------ALQPLEALEGDEAKLVCKITGSPTPTVEWFKE 1126

Query: 1664 -SGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQD--EVITQA---------P 1711
             + +  V   K  Y +      +P     ED   Y+  +  D  E  T A         P
Sbjct: 1127 KAKVVDVRRTKMEYTDDVATLTIPTTRP-EDKGMYKCVAKNDFGEASTSATLHINPVVKP 1185

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
             F   +K + V E   A FE R    G P+  VEW      IE S R   + +     L 
Sbjct: 1186 DFKTKLKPMEVTEESVAKFEVR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELI 1243

Query: 1772 MKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            +  V  +D+GTY C   N+ G A + + L V+ K
Sbjct: 1244 ISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK 1277



 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 60/225 (26%), Positives = 103/225 (45%), Gaps = 7/225 (3%)

Query: 4410 PPIFTK--KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            PP  T+  + +   + E E+    V   G P P +KW+++  PI+ S    I        
Sbjct: 821  PPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYT 880

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I     ED+  +   A+N+ GT+  + ++ +E  + +G      PS     Q   ++ 
Sbjct: 881  LNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIEASKPKGEA----PSLVSELQPQEISE 936

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+  +L+ KV+G     + W K+ + V  D R +   +  T TL I +A   D G Y+CV
Sbjct: 937  GEDAKLECKVSGEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCV 996

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            A N  G      E +V+    +++ +P+ K     PE+ EP  +K
Sbjct: 997  ATNELGSTSATTELLVNEKPVEEEKQPE-KPKVEKPEVEEPEVEK 1040



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 75/318 (23%), Positives = 131/318 (41%), Gaps = 22/318 (6%)

Query: 4376 KEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFD 4435
            KE +   T    + +   +Q+ +  VE P    +PP F  ++ P +V E  + +   +  
Sbjct: 2482 KEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGFEFKLIFKVV 2541

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
                  I+W ++        + +         L  +   ++D+  +  +  N+ G +  S
Sbjct: 2542 TTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSS 2601

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            A++ + +K R+       P      +++    G   R D +++      V W   G K+ 
Sbjct: 2602 ADISITQKTRK-------PEAIAPLKSIESVEGGQARFDVEMSAFPLPKVDWYHGGTKIT 2654

Query: 4556 PDIRNKILEE-DG---TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
               R KI++  DG    YTL+I      DSG Y+C+A N  G     ++  V  P     
Sbjct: 2655 HGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVKEPFI--A 2712

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671
            P+ + K   AP          +  +GQ I+ S KI  +P P + WYK  K +  SK   +
Sbjct: 2713 PEFEGKDITAP---------MVYKDGQDIKVSFKIKSRPKPIIAWYKDGKALTSSKRVTL 2763

Query: 4672 SRTADEYTLRISEAFPED 4689
            +   D Y L I +A  ED
Sbjct: 2764 TSRGDTYELIIKKATKED 2781



 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 63/202 (31%), Positives = 101/202 (50%), Gaps = 12/202 (5%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            ++ ++ + +K   PQ + + +D +  EG   RFD   TG P  +V W   + QI     +
Sbjct: 2015 SQAKLLVKKKGNRPQPIGMIRDIEGYEGGQARFDVHFTGNP--KVEWLHGEEQIIHGEKY 2072

Query: 439  KILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE-- 495
            KI  N     ++L++ ++   D G  TCVA N+SG+      LNV  K++ +AP FVE  
Sbjct: 2073 KISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNV--KDKHIAPMFVEDD 2130

Query: 496  RFSTLNVREGEP--VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
                + V  G+   V++N R  G P P + W KDG  +     + I +   +  L + +A
Sbjct: 2131 TGEPITVEAGKELNVIMNIR--GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKA 2188

Query: 554  KASDAAWYQCTAQNVAGSTATR 575
               DA  Y+C A+N  G TA+R
Sbjct: 2189 VPDDAGIYRCEAKNKLG-TASR 2209



 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 73/300 (24%), Positives = 122/300 (40%), Gaps = 31/300 (10%)

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            ++ G +    + + GNPRP V W+K+G  L               T R+  + + DS   
Sbjct: 2137 VEAGKELNVIMNIRGNPRPDVNWYKDGSFL-------------QQTGRMGISSRWDSYRL 2183

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
            T+    P+     +G    E+  +             T  R    ++E  +    P F+ 
Sbjct: 2184 TVFKAVPDD----AGIYRCEAKNK-----------LGTASRTVMVKVEELKGRGVPSFIT 2228

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
                  + EG      CRV+G+P P +TWF ++  +  D N  +   E    AL +  + 
Sbjct: 2229 GLFPVQIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHTD-NRVVASYEGSVSALELKEMK 2287

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            LSD+G+  C A N  G T+    + +  K+ +  P FV         E   + L+ +  G
Sbjct: 2288 LSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI--PTFVVGLKETEGLESSDMRLDVKIGG 2345

Query: 517  TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
             P P + + KD   I+ +   +I  DG   +L I   +  DA  Y+C   N+ G   + A
Sbjct: 2346 FPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEA 2405



 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 95/382 (24%), Positives = 163/382 (42%), Gaps = 47/382 (12%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+FT   K  V++ EGQ A  +  ++ T   +  +EWF     +  + R   +       
Sbjct: 726  PDFTKKLKP-VEVEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRYEFIEEGDSYT 782

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I  T   D  TY C A+N+ G+      L+  +K     P   T  +  E +   +  
Sbjct: 783  LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK---MFPPEITRPERTEKIVLLEKE 839

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
                 V  + +P   ++W+ +G+P+R S+R+          L+I  T+  D+G Y C A 
Sbjct: 840  ELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQ 899

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287
            NK G   T  TI+      V +E+ +P               + + PS  S   P+ I+ 
Sbjct: 900  NKMGTSST--TID------VQIEASKP---------------KGEAPSLVSELQPQEIS- 935

Query: 3288 IQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYC 3347
                    EG+ A  E ++    +P   +EWF + + +   +R R  +D     L I   
Sbjct: 936  --------EGEDAKLECKV--SGEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDA 985

Query: 3348 YEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRR 3407
              ++ G+Y+CVATN+LG  ST A  +    E  + + + P   +  +EK + +E+  V +
Sbjct: 986  TLDDEGDYKCVATNELG--STSATTELLVNEKPVEEEKQPE--KPKVEKPE-VEEPEVEK 1040

Query: 3408 KDTSVEEEKGKAPVFTVPLSNI 3429
             +  VEE     P    P+  +
Sbjct: 1041 PE--VEEPVSGKPEVETPVGEV 1060



 Score = 89.0 bits (211), Expect = 8e-17
 Identities = 102/505 (20%), Positives = 195/505 (38%), Gaps = 51/505 (10%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD-VS 130
            P F    K     +  + + + K+ G P P V + +    +V+  ++ +    + GD  S
Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKIL---EDGDRCS 2376

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ-PEGXXXXXXXXXXXXXYRHVSETVE-H 188
            L+I  + P D G Y C   N  G       I+  E                   E  E +
Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREHAPRFDGTDLGQSVTAQEGFELN 2436

Query: 189  KAYGTQGY---TTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITK-RY 244
            K +  +G    T    +    ++ +NG       +        ++ +E S   +      
Sbjct: 2437 KTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGE-SYSLVIIKVTKEDSGNYTCQAVSS 2495

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            +G++      +++       PP    +    +++EG + +   ++      ++ W K+G+
Sbjct: 2496 LGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGR 2555

Query: 305  RLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
                    E      + TL  +N    D+G Y         CIVT+ +    S  +    
Sbjct: 2556 AFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQ--------CIVTNKFGESSSSAD---- 2603

Query: 365  DQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
                              I I++K   P+ +   +  +  EG   RFD  ++  P P+V 
Sbjct: 2604 ------------------ISITQKTRKPEAIAPLKSIESVEGGQARFDVEMSAFPLPKVD 2645

Query: 425  WFINDRQIRDDYNHKILVNESGN---HALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            W+    +I     +KI+ +  G+   + L+I ++  +DSG   C+A N+ G T  +  L 
Sbjct: 2646 WYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLK 2705

Query: 482  VIEKEQVVAPKFVERFST--LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539
            V  KE  +AP+F  +  T  +  ++G+ + ++ +    P P I W KDG  +  +  + +
Sbjct: 2706 V--KEPFIAPEFEGKDITAPMVYKDGQDIKVSFKIKSRPKPIIAWYKDGKALTSSKRVTL 2763

Query: 540  HTDGGASTLDIPRAKASDAAWYQCT 564
             + G    L I +A   D    +CT
Sbjct: 2764 TSRGDTYELIIKKATKEDV---ECT 2785



 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 81/335 (24%), Positives = 134/335 (40%), Gaps = 39/335 (11%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDF--GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P  ++EW+    ++E   RF +  D   G   L + D    DSG+Y C  +N  GE  T 
Sbjct: 1504 PTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTK 1563

Query: 2999 STVYCTS------KDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPD------DDTGR 3046
            + +   +       D  ++  + P     LE  Q ++ S++ +    PD      DDT  
Sbjct: 1564 AKLQVDAVEVAPKTDKKLDEKEEPITV--LEH-QEVDMSVKVKGKYVPDKVLWFKDDTPV 1620

Query: 3047 PPEFTT--------VFKDIVDISEGQIAHYEA-------SLIPTGDQSMVIEWFYNGKTI 3091
                T          +  + D S     HY         + I T    + +EW  + K I
Sbjct: 1621 KTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPI 1680

Query: 3092 EASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF 3151
                 ++  +  G+  L +      D G Y C+ TNK G A     L  +   K  KP  
Sbjct: 1681 AKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANL--IVNEKAVKPVI 1738

Query: 3152 TTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG--FVVL 3209
               + N++ +++     FE  +    +P  ++ WYH    +   T  K + D G     L
Sbjct: 1739 VKPLSNLQ-VEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTL 1795

Query: 3210 DIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244
             +  +Q HDSG Y C A N+ G+  ++AT+   G+
Sbjct: 1796 IVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830



 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 10/197 (5%)

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
            G +   D G  PEFT   + +  + EG+    +A +   G  +  +EW  +G+ ++  HR
Sbjct: 16   GFEASPDKGTIPEFTKKLQPVT-VREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHR 72

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ 3156
            I+T +      L+I+ ++  D G Y C ATN+ GQA I+   E + K   +KP F   +Q
Sbjct: 73   IKTTFDGERCTLKIMPSERDDEGEYKCVATNEVGQATITT--EVLVKETLRKPEFKQKMQ 130

Query: 3157 NIEGLKDGQSAHFECTVVPVD-DPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQ 3215
             ++ L +G    F+   V +D  P  K+EW+ N   + +  R + + +     L I  T+
Sbjct: 131  PLQVL-EGDEVRFD---VRIDGKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTR 186

Query: 3216 NHDSGEYVCRAYNKYGE 3232
              D+  Y C A ++ G+
Sbjct: 187  LSDADTYKCIATSEAGK 203



 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 59/202 (29%), Positives = 92/202 (45%), Gaps = 12/202 (5%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G+ P F +  +  V++ EG        L  + +     EW  NG  +   +R++  +   
Sbjct: 1929 GKAPRFVSELRP-VEVFEGNEVSLVCKL--SAEAKPTFEWSRNGSPVRLDNRVQASFDGR 1985

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L+ L  K  D GTYSC A N +G A    KL  + K KG +P+    I++IEG + G
Sbjct: 1986 YSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKL--LVKKKGNRPQPIGMIRDIEGYEGG 2043

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG--FVVLDIAYTQNHDSGEY 3222
            Q A F+  V    +P  K+EW H  + + H  + K   + G     L +   ++ D G Y
Sbjct: 2044 Q-ARFD--VHFTGNP--KVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRY 2098

Query: 3223 VCRAYNKYGEDFTRATINCYGK 3244
             C A N+ G+    A +N   K
Sbjct: 2099 TCVASNESGDATLHANLNVKDK 2120



 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 62/237 (26%), Positives = 104/237 (43%), Gaps = 10/237 (4%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            ++WF +GK I  S R+          L I  T+  D+G+Y+C A NK G +  ++ ++  
Sbjct: 855  VKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIE 914

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
              K KG+ P   + +Q  E + +G+ A  EC V    +P   IEW+ + +P+    R++ 
Sbjct: 915  ASKPKGEAPSLVSELQPQE-ISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTDNRVRA 971

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260
              D     L I      D G+Y C A N+ G   T AT           E  QP+   K+
Sbjct: 972  DYDGKTSTLTIRDATLDDEGDYKCVATNELGS--TSATTELLVNEKPVEEEKQPEK-PKV 1028

Query: 3261 RELESLQGAQQQTPST--PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLK 3315
             + E ++  + + P    P +  P+  T + +V + V            P+   D+K
Sbjct: 1029 EKPE-VEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMK 1084



 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 79/270 (29%), Positives = 112/270 (41%), Gaps = 42/270 (15%)

Query: 1171 EISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            E SK K   P  V  L  P  +SEG++  LEC++   G+P   +EWF +   VT  +R +
Sbjct: 914  EASKPKGEAPSLVSELQ-PQEISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTDNRVR 970

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQ 1287
              YD     L I  AT  D G+Y   A N LGS   +  + V E+  +  + Q E+   +
Sbjct: 971  ADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK-PVEEEKQPEKPKVE 1029

Query: 1288 IQLLEDAARRTKQVREDIT--------VMQAPQFSRALHNIETVEGTNVHLE-------- 1331
               +E+      +V E ++        V + PQ   A   +E VE   + LE        
Sbjct: 1030 KPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKPTGEA 1089

Query: 1332 ----CRLQPV---------------GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDL 1372
                  LQP+               G  T  VEWF     +    R +  Y  D   L +
Sbjct: 1090 PKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVVDVRRTKMEYTDDVATLTI 1149

Query: 1373 LSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +  PED G+Y C A N  GEA TS  L +
Sbjct: 1150 PTTRPEDKGMYKCVAKNDFGEASTSATLHI 1179



 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 86/325 (26%), Positives = 136/325 (41%), Gaps = 38/325 (11%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E +  +    P+  +PLQD+ ++  G+ A F  Q++    PT  VEW+K    +    R 
Sbjct: 1467 ELLVNEKGAAPKIEKPLQDV-KVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRF 1523

Query: 820  TSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV-AARSTVTADLGIPE 876
              I +   G   L I   + ED+G Y     N +GE  + A ++V A       D  + E
Sbjct: 1524 MIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDE 1583

Query: 877  QRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIK---EGGFAHF---E 930
            +   I  T                 VP+     +  TP+K   + K   EG   +    +
Sbjct: 1584 KEEPI--TVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTD 1641

Query: 931  ARLEPIG----DST-------------LRVEWLKDGRPVEASSRITTFFNFGYVALTIKS 973
            A L+  G    +ST             ++VEWLKD +P+     +   F+ G   L +K 
Sbjct: 1642 ASLDDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKH 1701

Query: 974  VTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRT 1033
            V   D G Y C+  N +G AT  ANL IV +K +      P  ++ +  L+   +   R 
Sbjct: 1702 VVQQDKGVYKCKVTNKLGSATCGANL-IVNEKAV-----KPVIVKPLSNLQVEEKSLTRF 1755

Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEG 1058
            E ++    KPR +    GT K++EG
Sbjct: 1756 EVQIAGNPKPR-VAWYHGTTKLIEG 1779



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 55/181 (30%), Positives = 85/181 (46%), Gaps = 6/181 (3%)

Query: 3053 VFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILG 3112
            VF D   I+  +    + S+   G     I+W  + K I+ + R+ T       VL +  
Sbjct: 221  VFGDTAPINITEGDELDLSVRVRGKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSD 280

Query: 3113 TKTTDSGTYSCRATNKWGQA--EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170
             K  DSG Y C A ++ G A  E  V +E   K KG  P+FT  ++ +E + + ++A  E
Sbjct: 281  AKPEDSGRYKCTAKSEHGTASKEFDVNVEKA-KPKGVAPKFTKPLETLE-IMEKETARLE 338

Query: 3171 CTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
            CTV    +P    EW    QP++ + RIK   D   VVL++ + +  D   Y   A N+ 
Sbjct: 339  CTVT--GEPAPTTEWLKGDQPLKETQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNES 396

Query: 3231 G 3231
            G
Sbjct: 397  G 397



 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 114/518 (22%), Positives = 199/518 (38%), Gaps = 65/518 (12%)

Query: 1437 DESVTIK--PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF- 1493
            D  VT K  P  +TRP+  E ++  +       +  + +    V+WFK+G+P+    R  
Sbjct: 812  DLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLN 871

Query: 1494 -RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGL 1552
             RP  D     L+I     ED+G YTC A N +GT          S+T I          
Sbjct: 872  IRPRGDT--YTLNIHTTEPEDAGSYTCEAQNKMGT----------SSTTI---------- 909

Query: 1553 EQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVE 1612
              +Q+   + K     +V E+  Q           EI EG+ A  E ++      T  +E
Sbjct: 910  -DVQIEASKPKGEAPSLVSELQPQ-----------EISEGEDAKLECKVSGEPQPT--IE 955

Query: 1613 WYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
            W+ +++P+ + +R     +     L I     +D G Y C A N LG    +   +V+ K
Sbjct: 956  WFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK 1015

Query: 1673 KSIYLESQHEGALPRLNQLE-DTSKYQRHSAQDEVI----TQAPVFTMPMK-----DIRV 1722
                +E + +   P++ + E +  + ++   ++ V      + PV  +P +      + V
Sbjct: 1016 P---VEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEV 1072

Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGT 1782
             E      E  + P G+    V+ L+    +E           G     +++   +    
Sbjct: 1073 VETAPITLE-DMKPTGEAPKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVV 1131

Query: 1783 YTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQ 1842
               R   E  + V + T        +      +  + K     D         + +    
Sbjct: 1132 DVRRTKMEYTDDVATLT--------IPTTRPEDKGMYKCVAKNDFGEASTSATLHINPVV 1183

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
             P F T+L  P +++E   A +E R   +P P   VEW+     ++   R+R  ++    
Sbjct: 1184 KPDFKTKLK-PMEVTEESVAKFEVRSTGFPQP--EVEWFLGSTKIEDSGRFRVVSEQDRH 1240

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             L I  V  +D+G Y C   N  G A S   L V+ K+
Sbjct: 1241 ELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKD 1278



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 74/286 (25%), Positives = 120/286 (41%), Gaps = 40/286 (13%)

Query: 1965 KRAVQDDSFVVEK---PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021
            K   + D  V EK   P+  +P +  ++       L   +T + +P   V+W+ +G+P++
Sbjct: 806  KVTCRGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIR 865

Query: 2022 QGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLD 2081
            Q  R           L+I     ED G+Y C+A N +G    TSS  +D +       ++
Sbjct: 866  QSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG----TSSTTIDVQ-------IE 914

Query: 2082 EQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHL 2141
              +        K E P  + E QP             + + EG+ A  EC+V    +P  
Sbjct: 915  ASK-------PKGEAPSLVSELQP-------------QEISEGEDAKLECKVS--GEPQP 952

Query: 2142 TIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            TI+WF + + +   +R R  +D     L I     +D G Y C ATN+LG    T  L V
Sbjct: 953  TIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLV 1012

Query: 2202 AGHRNIILDTQHPNGLEKIRQLEAQGHST-RIEVEEPKISPPRFVT 2246
              +   + + + P    K+ + E +     + EVEEP    P   T
Sbjct: 1013 --NEKPVEEEKQPE-KPKVEKPEVEEPEVEKPEVEEPVSGKPEVET 1055



 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 67/234 (28%), Positives = 102/234 (43%), Gaps = 24/234 (10%)

Query: 3044 TGRP--PEFTT-VFKDIVDISEGQIAHYEASLIPT--GDQSMVIEWFYNGKTIEASHRIR 3098
            TGRP  P F     KD V +  GQ    E SL+ T  G  +  + W+ + K ++ S  ++
Sbjct: 1828 TGRPCAPTFVEDEVKDAVYVRGGQ----EVSLMLTINGFPTPDVMWYKDDKELQESQLVK 1883

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQ 3156
             +    M  L I      DSG Y C A N  G       V++E VD   G+ PRF + ++
Sbjct: 1884 IIPKGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVE-VD---GKAPRFVSELR 1939

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
             +E + +G      C +     P    EW  NG P+R   R++   D  +  L     + 
Sbjct: 1940 PVE-VFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKI 1996

Query: 3217 HDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQ 3270
             D G Y C A N +G   ++A +    KG       +P  +  IR++E  +G Q
Sbjct: 1997 EDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGMIRDIEGYEGGQ 2044



 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 95/391 (24%), Positives = 150/391 (38%), Gaps = 78/391 (19%)

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            +G+    V+W KDG+P+  SSR+          L I +    DAG YTC A N +G ++T
Sbjct: 848  LGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSST 907

Query: 996  SANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKI 1055
            +         D+  E+  P G                        + P  +  L+   +I
Sbjct: 908  TI--------DVQIEASKPKG------------------------EAPSLVSELQ-PQEI 934

Query: 1056 VEGQSAHFEARV--EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
             EG+ A  E +V  EPQ     T+EW+ + + +T+ NR++  +D     L I     +D 
Sbjct: 935  SEGEDAKLECKVSGEPQP----TIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDE 990

Query: 1114 GVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTR----HIEESKFVEPMY-- 1167
            G Y  VA N  G    +  + V  +   +     +   EK       +E+ +  EP+   
Sbjct: 991  GDYKCVATNELGSTSATTELLVNEKPVEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGK 1050

Query: 1168 -QIE----------------EISKSKPVFVQ---PLSNPPPVS---------EGKNIHLE 1198
             ++E                E+ ++ P+ ++   P    P V          EG    L 
Sbjct: 1051 PEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKPTGEAPKVVDALQPLEALEGDEAKLV 1110

Query: 1199 CRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHL 1258
            C++   G PT  VEWF     V    R K  Y      L I      D G Y   A N  
Sbjct: 1111 CKIT--GSPTPTVEWFKEKAKVVDVRRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDF 1168

Query: 1259 GSAHTSAIVRV--IERSDIVTDTQNEQAIEQ 1287
            G A TSA + +  + + D  T  +  +  E+
Sbjct: 1169 GEASTSATLHINPVVKPDFKTKLKPMEVTEE 1199



 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 102/485 (21%), Positives = 182/485 (37%), Gaps = 49/485 (10%)

Query: 103  VSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC--SVY 160
            V W +   P+ +       ++   G  +L++K +   D+G Y C   N+ G A C  ++ 
Sbjct: 1671 VEWLKDDKPIAKDRHLKEAFHN--GVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728

Query: 161  IQPEGXXXXXXXXXXXXXYRHVSET-VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTD 219
            +  +                  S T  E +  G           T K+    GT +   +
Sbjct: 1729 VNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLI--EGTIYKMLE 1786

Query: 220  DFKVDTFEYRLLREVSFRESITKRY-VGESDVQISTEIDRSLG-PVSPPKIAQKPRNSK- 276
            D    TF   +         + K   V E+   IS       G P +P  +  + +++  
Sbjct: 1787 DSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDEVKDAVY 1846

Query: 277  LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
            ++ G +    + ++G P P V W+K+ + L  S   +II   N   L +     +DSG Y
Sbjct: 1847 VRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIY 1906

Query: 337  TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
                     C+  + + +V                     R  + R+E+  KA  P+FV 
Sbjct: 1907 R--------CVAKNTHGSVS--------------------RTFDVRVEVDGKA--PRFVS 1936

Query: 397  VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNV 455
              +  +V EG      C+++    P   W  N   +R D  +++  +  G ++ L   N 
Sbjct: 1937 ELRPVEVFEGNEVSLVCKLSAEAKPTFEWSRNGSPVRLD--NRVQASFDGRYSTLKFLNA 1994

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
             + D G  +C+A+N  G  + Q +L V  K++   P+ +     +   EG     +    
Sbjct: 1995 KIEDQGTYSCLAKNVFGSASSQAKLLV--KKKGNRPQPIGMIRDIEGYEGGQARFDVHFT 2052

Query: 516  GTPTPRITWQKDGVPIIPNPELRIHTDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
            G   P++ W      II   + +I  + G    +L +   K  D   Y C A N +G   
Sbjct: 2053 G--NPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDAT 2110

Query: 574  TRARL 578
              A L
Sbjct: 2111 LHANL 2115



 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 111/454 (24%), Positives = 177/454 (38%), Gaps = 72/454 (15%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSLDITHTY 2839
            N+   EGD I  +  V    +PT  ++WF  ++ +    R+    D      SL I +  
Sbjct: 422  NVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAK 479

Query: 2840 EEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGR 2899
              DSG+Y C+ATN                     DT    GKA  EA  Q EE  +A   
Sbjct: 480  PLDSGVYICQATN---------------------DT----GKATAEAEIQIEELLVA--- 511

Query: 2900 RPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSR 2959
                       PE+    A +  L+E   + LE  V  K  P+  + W  + K L +  R
Sbjct: 512  -----------PEFAEEEATQLTLIEDDDMTLELHVTGKPKPE--VHWTKDNKPLTEDDR 558

Query: 2960 FKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGT 3019
              +        +D++ V   DSG Y C+A NK G    ++  +  + + L         +
Sbjct: 559  IIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAG---VNTRTFIVNVEVLFVAGI----S 611

Query: 3020 EGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQS 3079
            + +  I+ +   L K+P        G  PE T   +++ ++ EG           TG  +
Sbjct: 612  QVIGSIRFI--VLAKKP-------AGEAPEITESLQEMEEL-EGNPVTLTCKF--TGTPA 659

Query: 3080 MVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
             V EWF     +    R +         L I  T+  D+  Y     N  G    SVK E
Sbjct: 660  PVAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG----SVKSE 715

Query: 3140 C-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI 3198
              V  +   +P FT  ++ +E +++GQ A  +  VV    P+  +EW+     +  + R 
Sbjct: 716  TRVRITALVRPDFTKKLKPVE-VEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRY 772

Query: 3199 KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            + + +     L I  T   D   Y C A N+ G+
Sbjct: 773  EFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGK 806



 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 100/418 (23%), Positives = 162/418 (38%), Gaps = 42/418 (10%)

Query: 3684 EITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            ++ IE  KP    P    E++   ++ EG     +C+V   G+P   I+WF +  P  T 
Sbjct: 910  DVQIEASKPKGEAPSLVSELQPQ-EISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTD 966

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801
            +RV    D     L I      D G+Y C ATN+ GS + T ++  + K   V E + P+
Sbjct: 967  NRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKP--VEEEKQPE 1024

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861
                EK  E+E   +     EEP+   P     ++++   E  + V     VE  E   +
Sbjct: 1025 KPKVEK-PEVEEPEVEKPEVEEPVSGKP-----EVETPVGEVPQEVLAPVTVEVVETAPI 1078

Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICR-------AVNDFGEDF 3914
             +E      + P+G   + V      +L  L     D  + +C+        V  F E  
Sbjct: 1079 TLE-----DMKPTGEAPKVV-----DALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKA 1128

Query: 3915 TKATISCKKL--PDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQP 3972
                +   K+   D +    +P    R E     +   K    E   T   L+ ++    
Sbjct: 1129 KVVDVRRTKMEYTDDVATLTIP--TTRPEDKGMYKCVAKNDFGEA-STSATLH-INPVVK 1184

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P F T+++    + E    KFE  +   G P  +VEWF     +    RF  + +     
Sbjct: 1185 PDFKTKLKPM-EVTEESVAKFE--VRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHE 1241

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK---PGIVYDSQLPKHMKSIEKI 4087
            +    V  +D+G Y C   N  G   ++A +K   K   P  V D   P  ++  E I
Sbjct: 1242 LIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKDCAPEFVGDQAAPIVVRQGEDI 1299



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 71/304 (23%), Positives = 129/304 (42%), Gaps = 37/304 (12%)

Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
            + I  G     + W  +G  I +S+ +          L I+     DSG Y+C+A +  G
Sbjct: 2438 TFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLG 2497

Query: 3131 QAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189
            +A  S  L+    K K + P F + +  ++ +++G    F+     V   D KIEW  +G
Sbjct: 2498 KASQSFDLKVEAPKVKEEPPSFLSELPPLQ-VREG--FEFKLIFKVVTTKDSKIEWRKDG 2554

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYL 3249
            +        +   D   + L        D+G Y C   NK+GE  + A I+      +  
Sbjct: 2555 RAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADIS------ITQ 2608

Query: 3250 ESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPV 3309
            ++ +P+++A ++ +ES++G Q +     SA P   +      TK+  G       +++  
Sbjct: 2609 KTRKPEAIAPLKSIESVEGGQARFDVEMSAFPLPKVDWYHGGTKITHGG----RYKIIQS 2664

Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTK 3369
             D D  V                    + ++I  + Y    +SG Y+C+ATN+ G  + K
Sbjct: 2665 TDGDRPV--------------------YTLIIESLKY---TDSGTYKCIATNEGGVTTIK 2701

Query: 3370 ANLK 3373
            ++LK
Sbjct: 2702 SDLK 2705



 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 37/197 (18%)

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
            +G+P   + WF +G+P    SR++         L+I      DAG YTC A NK G+++T
Sbjct: 848  LGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSST 907

Query: 3782 TAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841
            T         D+ +E+  P+G +   + EL+       P+E                  +
Sbjct: 908  TI--------DVQIEASKPKGEAPSLVSELQ-------PQE------------------I 934

Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGE 3901
             E E  + EC+V    +P+  IEW+++ + + + +R R  YD    +L I     +D G+
Sbjct: 935  SEGEDAKLECKV--SGEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGD 992

Query: 3902 YICRAVNDFGEDFTKAT 3918
            Y C A N+ G   T AT
Sbjct: 993  YKCVATNELGS--TSAT 1007



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 43/115 (37%), Positives = 61/115 (53%), Gaps = 5/115 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F K ++   V EG  + L+A +     PT  VEW  +G  VQ  HR KTT+D     L
Sbjct: 27   PEFTKKLQPVTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092
             I+ +  +D G Y C ATN VG+A  T+ V V  K  L      +Q+++ +Q LE
Sbjct: 85   KIMPSERDDEGEYKCVATNEVGQATITTEVLV--KETLRKPEF-KQKMQPLQVLE 136



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 46/159 (28%), Positives = 70/159 (44%), Gaps = 5/159 (3%)

Query: 422  EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLN 481
            +V W  +D+ I  D + K   + +G   L++ +V   D GV  C   NK G     C  N
Sbjct: 1670 KVEWLKDDKPIAKDRHLKEAFH-NGVCTLILKHVVQQDKGVYKCKVTNKLGSAT--CGAN 1726

Query: 482  VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            +I  E+ V P  V+  S L V E        +  G P PR+ W      +I     ++  
Sbjct: 1727 LIVNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKMLE 1786

Query: 542  DGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D G    TL +  ++  D+  Y+C A N AG   ++A L
Sbjct: 1787 DSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATL 1825



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 95/441 (21%), Positives = 170/441 (38%), Gaps = 70/441 (15%)

Query: 1803 QSKASLQLESQH----ESALQKIQQLEDSSRYQRREDVEVAVNQAPR--FITQLNGPTKL 1856
            + K S+ LE +H    + AL K+    +S       + E+ VN+A    F  +      +
Sbjct: 368  RDKDSVVLEVRHVELDDEALYKVVAKNESG--VATSEAELLVNEATEKPFFKKTPQNVTV 425

Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYRTSNDFG-FAALDILTVYGEDS 1914
             EG     + R+   P+P   V+W+    KV + G      ++ G   +L I      DS
Sbjct: 426  LEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDS 483

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G Y C+A N+ G+A +   + +            E  L   ++ E+++     ++DD   
Sbjct: 484  GVYICQATNDTGKATAEAEIQI------------EELLVAPEFAEEEATQLTLIEDDDMT 531

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            +E    GK                        P   V W  + +P+ +  R    +    
Sbjct: 532  LELHVTGK------------------------PKPEVHWTKDNKPLTEDDRIIIDHKGDS 567

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094
              +DI+     D+GTY C+A N  G    T  V V+    L++  +  Q +  I+ +   
Sbjct: 568  CIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEV---LFVAGI-SQVIGSIRFIVLA 623

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            ++P        G+ P    +L  +E L EG+     C+      P    +WF     +R 
Sbjct: 624  KKP-------AGEAPEITESLQEMEEL-EGNPVTLTCKF--TGTPAPVAEWFKASTPVRD 673

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
            G RY+ T       L I  T  +D+  Y     N +G   +   +++            P
Sbjct: 674  GRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITA-------LVRP 726

Query: 2215 NGLEKIRQLEA-QGHSTRIEV 2234
            +  +K++ +E  +G   R++V
Sbjct: 727  DFTKKLKPVEVEEGQEARLDV 747



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 83/366 (22%), Positives = 141/366 (38%), Gaps = 68/366 (18%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P+ +++W+++  P++   R+   +D     L       ED   Y   A NELG   TS
Sbjct: 1406 GKPQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTS 1465

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857
            + L V  K           A  KI+        +  +DV+V   +   F TQ++G     
Sbjct: 1466 AELLVNEK----------GAAPKIE--------KPLQDVKVDAGKKATFNTQVSG----- 1502

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF--GFAALDILTVYGEDSG 1915
                            P   VEW+    +++   R+   +D   G   L I     EDSG
Sbjct: 1503 ---------------TPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSG 1547

Query: 1916 EYTCKAINNLGQAVSSIRLNVQSKESIIR-DSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
             Y C   N++G+  +  +L V + E   + D + +   E I  LE             +V
Sbjct: 1548 VYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYV 1607

Query: 1975 VEKPQFGK---PIKNAEV----TEGHPVHLEATLTPVNDP-------------------- 2007
             +K  + K   P+K        +EG   +L  T   ++D                     
Sbjct: 1608 PDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLI 1667

Query: 2008 TMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067
             ++VEW  + +P+ +    K  +  G   L + +   +D G Y CK TN +G A   +++
Sbjct: 1668 IVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANL 1727

Query: 2068 KVDAKS 2073
             V+ K+
Sbjct: 1728 IVNEKA 1733



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 65/255 (25%), Positives = 104/255 (40%), Gaps = 31/255 (12%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI--FRFGYI 694
            P+   PL+ V    G K  F T++   G PT ++EW K    +E   RF  I   + G  
Sbjct: 1477 PKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVF 1534

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV----TPRATIERTSQHPETLQYIQQL 750
             L +     +DSG Y C   +  G  +TKA L V        T ++  +  E +  ++  
Sbjct: 1535 QLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQ 1594

Query: 751  E-DYS-----KYQHQESI--EEQTSQRPQFIRPLQDLGEL--------QEGRNAHFEAQL 794
            E D S     KY   + +  ++ T  +    R +   G +              H+  + 
Sbjct: 1595 EVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCES 1654

Query: 795  TPVSDPT-------MRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRA 847
            T     T       ++VEW KD +PI     +   F+ G  +L + H+  +D G Y  + 
Sbjct: 1655 TTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKV 1714

Query: 848  VNKLGEAISTASIRV 862
             NKLG A   A++ V
Sbjct: 1715 TNKLGSATCGANLIV 1729



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 56/261 (21%), Positives = 106/261 (40%), Gaps = 18/261 (6%)

Query: 4261 PETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGD----KVTSNTVAK 4316
            P  EW     +  + + Y  ++E ++  +I ++ +R+    Y         KVT     K
Sbjct: 755  PNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLK 814

Query: 4317 SMAQRYEDNL---DQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVV 4373
               + +   +   ++TE++     ++ V     + +P       K+    +Q        
Sbjct: 815  VTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRP 874

Query: 4374 GDKEITRKITSTE-------TTEIEHKAQTQERVVEGPVKPSKP----PIFTKKMQPCRV 4422
                 T  I +TE       T E ++K  T    ++  ++ SKP    P    ++QP  +
Sbjct: 875  RGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIEASKPKGEAPSLVSELQPQEI 934

Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFA 4482
             E E A+ E +  GEP P I+W++++ P+      +       S L IR   ++D   + 
Sbjct: 935  SEGEDAKLECKVSGEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTLTIRDATLDDEGDYK 994

Query: 4483 AVAENRGGTAKCSANLVVEEK 4503
             VA N  G+   +  L+V EK
Sbjct: 995  CVATNELGSTSATTELLVNEK 1015



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 52/196 (26%), Positives = 84/196 (42%), Gaps = 9/196 (4%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            TG  P+     + + +  EG  A     +  TG  +  +EWF     +    R +  Y  
Sbjct: 1086 TGEAPKVVDALQPL-EALEGDEAKLVCKI--TGSPTPTVEWFKEKAKVVDVRRTKMEYTD 1142

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
             +  L I  T+  D G Y C A N +G+A  S  L     +   KP F T ++ +E + +
Sbjct: 1143 DVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHI---NPVVKPDFKTKLKPME-VTE 1198

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
               A FE  V     P  ++EW+     +  S R + VS+     L I+  +  D+G Y 
Sbjct: 1199 ESVAKFE--VRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYK 1256

Query: 3224 CRAYNKYGEDFTRATI 3239
            C   N+ G  ++RA +
Sbjct: 1257 CTLANQAGTAYSRADL 1272



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 64/283 (22%), Positives = 125/283 (44%), Gaps = 47/283 (16%)

Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297
            K+ PP  +T    T  +   +       V  + +P   ++++ +GK ++ ++R +I    
Sbjct: 818  KMFPPE-ITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRG 876

Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELE 2357
               +L+I    PEDAG Y+ +A N +G  ++ I + +        E+ +P+G        
Sbjct: 877  DTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQI--------EASKPKG-------- 920

Query: 2358 SAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEK 2417
                    E P  V+  +P           I EG+ A  +C++   G+P   +EWF++++
Sbjct: 921  --------EAPSLVSELQP---------QEISEGEDAKLECKV--SGEPQPTIEWFKDDE 961

Query: 2418 LIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLE 2477
             +   +R+   +D    ++TI     +DEG Y C A+N LG                 L 
Sbjct: 962  PVTTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTEL---------LV 1012

Query: 2478 TQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSEL 2520
             + P  +++ ++ E+P   + E  + E EKP   + ++G  E+
Sbjct: 1013 NEKP--VEEEKQPEKPKVEKPEVEEPEVEKPEVEEPVSGKPEV 1053



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 80/377 (21%), Positives = 149/377 (39%), Gaps = 24/377 (6%)

Query: 1837 EVAVNQ---APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
            E+ VN+   AP+    L    K+  G+ A +  ++   P P   VEW+    +++   R+
Sbjct: 1467 ELLVNEKGAAPKIEKPLQD-VKVDAGKKATFNTQVSGTPTPE--VEWFKGESIVEDKGRF 1523

Query: 1894 RTSNDF--GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR-DSQHES 1950
               +D   G   L I     EDSG Y C   N++G+  +  +L V + E   + D + + 
Sbjct: 1524 MIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDE 1583

Query: 1951 ALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMR 2010
              E I  LE             +V +K  + K     +      +H E  +  +      
Sbjct: 1584 KEEPITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDAS 1643

Query: 2011 VEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK-- 2068
            ++   + R  +   +  TT     + + + +   +           A    V T  +K  
Sbjct: 1644 LDDAGHYR-CESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHV 1702

Query: 2069 VDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAH 2128
            V    G+Y       + K   +L        +   +   +PV +  L++L+ ++E     
Sbjct: 1703 VQQDKGVY-------KCKVTNKLGSATCGANLIVNEKAVKPVIVKPLSNLQ-VEEKSLTR 1754

Query: 2129 FECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE--DSGTYMCKA 2186
            FE ++    +P   + W+H   K+  G  Y+   D G     ++   ++  DSG Y C A
Sbjct: 1755 FEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVA 1812

Query: 2187 TNKLGEAVNTCTLKVAG 2203
             N+ G+A++  TL+V G
Sbjct: 1813 VNEAGKAISQATLEVTG 1829



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 51/189 (26%), Positives = 79/189 (41%), Gaps = 12/189 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP F +    +  + EG        ++ T D    IEW  +G+           +    +
Sbjct: 2516 PPSFLSELPPL-QVREGFEFKLIFKVVTTKDSK--IEWRKDGRAFTPGGNSEFSFDGRNI 2572

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L        D+G Y C  TNK+G++  S  +    K++  KP     +++IE ++ GQ 
Sbjct: 2573 TLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQKTR--KPEAIAPLKSIESVEGGQ- 2629

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK----TVSDFGFVVLDIAYTQNHDSGEY 3222
            A F+  +     P  K++WYH G  + H  R K    T  D     L I   +  DSG Y
Sbjct: 2630 ARFDVEMSAFPLP--KVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTY 2687

Query: 3223 VCRAYNKYG 3231
             C A N+ G
Sbjct: 2688 KCIATNEGG 2696



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 3/139 (2%)

Query: 1287 QIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEW 1346
            Q+ +  D      + R  IT +  P F++ L  +E  EG    L+ R+  VG  T  VEW
Sbjct: 702  QVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEVEEGQEARLDVRV--VGTPTPNVEW 759

Query: 1347 FCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
            FC    +    R+    E D   L + +   +D   Y C A+NQ+G+      L+V  +K
Sbjct: 760  FCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKV-TEK 818

Query: 1407 DLILESQHPSGLEKIQYLE 1425
                E   P   EKI  LE
Sbjct: 819  MFPPEITRPERTEKIVLLE 837



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 101/382 (26%), Positives = 153/382 (40%), Gaps = 39/382 (10%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF--GI 3339
            PK    +QDV K+  G+ A F  ++     P+  VEWF     +    R+    D   G+
Sbjct: 1477 PKIEKPLQDV-KVDAGKKATFNTQVSGTPTPE--VEWFKGESIVEDKGRFMIIDDAKEGV 1533

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQT 3399
              L I     E+SG Y+CV  N +G   TKA L+  + E      +     E  +  L+ 
Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEH 1593

Query: 3400 LE-DSMVRRKDTSVEEE----KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
             E D  V+ K   V ++    K   PV T     I +  EG   +    LT TD      
Sbjct: 1594 QEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHS--EGRMYY----LTLTDASLDDA 1647

Query: 3455 EWYWNGKSLKAGSRFRTFCDFGFVILE-ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
              Y    + K G+   TF     V +E +    P     +L  A++N    V T  +K  
Sbjct: 1648 GHYRCESTTKLGTTISTFLII--VKVEWLKDDKPIAKDRHLKEAFHN---GVCTLILK-- 1700

Query: 3514 GKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENS 3573
               +++   Q  KG+     K+    G S T        E    P      S+L + E S
Sbjct: 1701 ---HVV---QQDKGVYKC--KVTNKLG-SATCGANLIVNEKAVKPVIVKPLSNLQVEEKS 1751

Query: 3574 SAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG---FVILEIGGVYQRDAGLY 3630
               FE ++    +   RV W+H    L+ G+  K + D G   F ++ +    + D+G+Y
Sbjct: 1752 LTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLI-VNDSQRHDSGVY 1808

Query: 3631 TCKATNRHGEATVSCKLQVKGR 3652
             C A N  G+A     L+V GR
Sbjct: 1809 KCVAVNEAGKAISQATLEVTGR 1830



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 39/118 (33%), Positives = 61/118 (51%), Gaps = 6/118 (5%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F  +L  P  + EG+    + R++  P P   VEW  +G+ +Q  HR +T+ D     
Sbjct: 27   PEFTKKLQ-PVTVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCT 83

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
            L I+    +D GEY C A N +GQA  +I   V  KE+ +R  + +  ++ +Q LE D
Sbjct: 84   LKIMPSERDDEGEYKCVATNEVGQA--TITTEVLVKET-LRKPEFKQKMQPLQVLEGD 138



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 78/339 (23%), Positives = 136/339 (40%), Gaps = 25/339 (7%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDF--GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            +VEWFK    V    RF  I D   G   L I D   EDSG+Y C   N +G  +   +L
Sbjct: 1507 EVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKL 1566

Query: 1535 TCRSTTDIVRSTQN-EAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQ 1593
               +     ++ +  +   E I VLE +       +  +      +       V+    +
Sbjct: 1567 QVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTR 1626

Query: 1594 RAHFERRL--IPVSDATLK-VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTY 1650
            + H E R+  + ++DA+L     Y      K G+  +      F+ +  +  L +D    
Sbjct: 1627 KIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTIST-----FLIIVKVEWLKDDKPIA 1681

Query: 1651 TCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPR--LNQLEDTSKYQRHSAQDEVIT 1708
              R +    EA  +G+  +  K   ++  Q +G       N+L   +        ++ + 
Sbjct: 1682 KDRHLK---EAFHNGVCTLILK---HVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAVK 1735

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
              PV   P+ +++V E     FE ++   G+PK RV W      +        + D G  
Sbjct: 1736 --PVIVKPLSNLQVEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791

Query: 1769 ALNMKYVNPE--DSGTYTCRAINELGEAVTSSTLFVQSK 1805
               +   + +  DSG Y C A+NE G+A++ +TL V  +
Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830



 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 63/278 (22%), Positives = 119/278 (42%), Gaps = 14/278 (5%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            +T R PEF    + +  + EG    ++  +   G  +  +EWF N   I+   R   +  
Sbjct: 118  ETLRKPEFKQKMQPL-QVLEGDEVRFDVRI--DGKPTPKVEWFKNRTKIDNEGRFEIIDE 174

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
              +  L I  T+ +D+ TY C AT++ G++   V+L   +K+   +    T   NI    
Sbjct: 175  EDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINIT--- 231

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
              +    + +V     P  +I+W  + +P++ + R+ T +     VL ++  +  DSG Y
Sbjct: 232  --EGDELDLSVRVRGKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRY 289

Query: 3223 VCRAYNKYGEDFTRATINC--YGKGGVYLESLQPDSLAKIRELESLQ----GAQQQTPST 3276
             C A +++G       +N       GV  +  +P    +I E E+ +       +  P+T
Sbjct: 290  KCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKETARLECTVTGEPAPTT 349

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314
               +  + + + Q +    +  S   E R V +DD  L
Sbjct: 350  EWLKGDQPLKETQRIKIERDKDSVVLEVRHVELDDEAL 387



 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 74/277 (26%), Positives = 117/277 (42%), Gaps = 39/277 (14%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474
            EKG AP    PL +++ +  G+ A F  +++ T  P  +VEW+     ++   RF    D
Sbjct: 1472 EKGAAPKIEKPLQDVK-VDAGKKATFNTQVSGTPTP--EVEWFKGESIVEDKGRFMIIDD 1528

Query: 3475 F--GFVILEISPTYPEDSGEYLCRAYNNYG----------EAVTTA---SMKVQGKRN-- 3517
               G   L I    PEDSG Y C  +N+ G          +AV  A     K+  K    
Sbjct: 1529 AKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPI 1588

Query: 3518 IILESQ---LPKGMEGTI--DKIAALEGYSGTVDTLTPEAES-GNPPEFTTTPSDLILSE 3571
             +LE Q   +   ++G    DK+   +  +      T +  S G     T T + L    
Sbjct: 1589 TVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASL---- 1644

Query: 3572 NSSAHFECRLIPVNDSSM-------RVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQ 3624
            + + H+ C       +++       +VEW  + KP+     +K     G   L +  V Q
Sbjct: 1645 DDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQ 1704

Query: 3625 RDAGLYTCKATNRHGEATVSCKLQV--KGRQGIILEP 3659
            +D G+Y CK TN+ G AT    L V  K  + +I++P
Sbjct: 1705 QDKGVYKCKVTNKLGSATCGANLIVNEKAVKPVIVKP 1741



 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 70/305 (22%), Positives = 120/305 (39%), Gaps = 34/305 (11%)

Query: 278  QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337
            QEG +      + G PRP VTW K+G          +I++ N  +LR R   +S S    
Sbjct: 2430 QEGFELNKTFIIRGKPRPTVTWMKDGN---------VISSSNGVSLRQRG--ESYSLVII 2478

Query: 338  LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
             + +  +G        ++   ++S+          D +     E  ++ E+   P F+  
Sbjct: 2479 KVTKEDSGNYTCQAVSSLGKASQSF----------DLKV----EAPKVKEEP--PSFLSE 2522

Query: 398  CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457
                 V EG   +   +V      ++ W  + R      N +    +  N  L   N TL
Sbjct: 2523 LPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSF-DGRNITLAFKNATL 2581

Query: 458  SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
             D+G   C+  NK GE++    +++ +K +   P+ +    ++   EG     +      
Sbjct: 2582 KDAGRYQCIVTNKFGESSSSADISITQKTR--KPEAIAPLKSIESVEGGQARFDVEMSAF 2639

Query: 518  PTPRITWQKDGVPIIPNPELRI--HTDGG--ASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
            P P++ W   G  I      +I   TDG     TL I   K +D+  Y+C A N  G T 
Sbjct: 2640 PLPKVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTT 2699

Query: 574  TRARL 578
             ++ L
Sbjct: 2700 IKSDL 2704



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 62/259 (23%), Positives = 102/259 (39%), Gaps = 31/259 (11%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF--GY 1767
            AP    P++D++V   + A F  ++   G P   VEW +    +E   R   + D   G 
Sbjct: 1476 APKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-----KASLQLESQHES-ALQKI 1821
              L ++   PEDSG Y C   N++GE  T + L V +     K   +L+ + E   + + 
Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEH 1593

Query: 1822 QQLEDSSRYQR----------REDVEVAVNQAPRFITQ----LNGPTKLSEGQSAHYECR 1867
            Q+++ S + +           ++D  V  N   +  ++        T  S   + HY C 
Sbjct: 1594 QEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCE 1653

Query: 1868 IEPYPDPN-------MRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920
                           ++VEW  + K +      + +   G   L +  V  +D G Y CK
Sbjct: 1654 STTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCK 1713

Query: 1921 AINNLGQAVSSIRLNVQSK 1939
              N LG A     L V  K
Sbjct: 1714 VTNKLGSATCGANLIVNEK 1732



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 7/210 (3%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI--L 4468
            P   K +Q  +V   ++A F  +  G P P ++W++    +++   F I   + + +  L
Sbjct: 1477 PKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQL 1536

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            +I     EDS V+  V  N  G  +  A L V+      +            + + V   
Sbjct: 1537 VIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPK---TDKKLDEKEEPITVLEH 1593

Query: 4529 QLVRLDTKVTGTK-PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            Q V +  KV G   P  V W K+   V+ +   KI  E   Y L + +A   D+G Y C 
Sbjct: 1594 QEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCE 1653

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTK 4617
            +    G        +V +   KD  KP  K
Sbjct: 1654 STTKLGTTISTFLIIVKVEWLKD-DKPIAK 1682



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 3/109 (2%)

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            RT  VR ++   +AP+F   L  +E  EG  V L C+L      T   EW  NG P++  
Sbjct: 1919 RTFDVRVEVDG-KAPRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLD 1975

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            +R + +++  Y  L  L+   ED G Y+C A N  G A +   L V  K
Sbjct: 1976 NRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK 2024



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 87/360 (24%), Positives = 139/360 (38%), Gaps = 77/360 (21%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+ LQ +  ++EG+    D R+   G PT  VEW  + + ++D  RI  T D    +
Sbjct: 27   PEFTKKLQPV-TVREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHRIKTTFDGERCT 83

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495
            + I     +DEG Y C A+N +G+              ++   + PE  +K+Q L     
Sbjct: 84   LKIMPSERDDEGEYKCVATNEVGQ------ATITTEVLVKETLRKPEFKQKMQPL----- 132

Query: 2496 RRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555
                            QVL G           ++ R+   G P+ + EW+ N  ++    
Sbjct: 133  ----------------QVLEG-------DEVRFDVRI--DGKPTPKVEWFKNRTKIDNEG 167

Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPES 2615
            RF    +    +L I+    +DA  Y C A + AG                       +S
Sbjct: 168  RFEIIDEEDLYSLIIDDTRLSDADTYKCIATSEAG-----------------------KS 204

Query: 2616 WEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLK 2675
               ++L        PE+F DT    API          + EG    L+  V  R  P  +
Sbjct: 205  TCIVELSVKEKTSAPEVFGDT----API---------NITEGDE--LDLSVRVRGKPKPE 249

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            I+W K+   +    RL +T       L ++  + +DSG Y C A +  G A     + +E
Sbjct: 250  IKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVE 309



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 85/380 (22%), Positives = 141/380 (37%), Gaps = 26/380 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P  +  L+     EG     E ++   G+P   IEW K+ + +   +R  + +     +L
Sbjct: 923  PSLVSELQPQEISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTDNRVRADYDGKTSTL 980

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
             +    + D G+Y C A +  G       L V  +   E   + PE  + +++ E     
Sbjct: 981  TIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPVEEE--KQPEKPK-VEKPEVEEPE 1037

Query: 757  QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
              +  +EE  S +P+   P+   GE+ +   A    ++   +  T+     +D +P   +
Sbjct: 1038 VEKPEVEEPVSGKPEVETPV---GEVPQEVLAPVTVEVVETAPITL-----EDMKPTGEA 1089

Query: 817  SRITSIFN-FGYVSLNIMHLRAEDAGSYT--VRAVNKLGEAISTASIRVAARSTVTADLG 873
             ++         +  +   L  +  GS T  V    +  + +     ++     V A L 
Sbjct: 1090 PKVVDALQPLEALEGDEAKLVCKITGSPTPTVEWFKEKAKVVDVRRTKMEYTDDV-ATLT 1148

Query: 874  IPEQR---RYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFE 930
            IP  R   + + K                   P    KP+FKT +K  + + E   A FE
Sbjct: 1149 IPTTRPEDKGMYKCVAKNDFGEASTSATLHINP--VVKPDFKTKLKP-MEVTEESVAKFE 1205

Query: 931  ARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAI 990
             R    G     VEW      +E S R           L I  V V DAG Y C   N  
Sbjct: 1206 VR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQA 1263

Query: 991  GQATTSANLTIVTKKDIIAE 1010
            G A + A+L  V +KD   E
Sbjct: 1264 GTAYSRADLK-VKEKDCAPE 1282



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 42/150 (28%), Positives = 73/150 (48%), Gaps = 5/150 (3%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI+ L  +  KEGD     C V     PT  I WF +N P+ +  R  ++++ S  +L++
Sbjct: 2226 FITGLFPVQIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSALEL 2283

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
                  D+G+Y C ATNS+GS ++S  +       I       +   GLE+ +   + ++
Sbjct: 2284 KEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLESSDMRLDVKI 2343

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVE 2925
                RP+V   E+ K   +I  +  H+++E
Sbjct: 2344 GGFPRPTV---EFYKDYDLIVDSERHKILE 2370



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 43/161 (26%), Positives = 74/161 (45%), Gaps = 6/161 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP  +++L  P ++SEG+ A  EC++   P P   +EW+ + + + + +R R   D   
Sbjct: 921  EAPSLVSELQ-PQEISEGEDAKLECKVSGEPQPT--IEWFKDDEPVTTDNRVRADYDGKT 977

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
            + L I     +D G+Y C A N LG   ++  L V  K  +  + Q E    +   +E+ 
Sbjct: 978  STLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK-PVEEEKQPEKPKVEKPEVEEP 1036

Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLT 2002
               K  V++   V  KP+   P+         PV +E   T
Sbjct: 1037 EVEKPEVEEP--VSGKPEVETPVGEVPQEVLAPVTVEVVET 1075



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 38/146 (26%), Positives = 72/146 (49%), Gaps = 8/146 (5%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P+F++ L  +   EG  + L+ R++  G  T  VEW  +G+ ++  HR +  ++ +   L
Sbjct: 27   PEFTKKLQPVTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DTSR 1429
             ++    +D G Y C ATN++G+A  +  + V   K+ + + +    ++ +Q LE D  R
Sbjct: 85   KIMPSERDDEGEYKCVATNEVGQATITTEVLV---KETLRKPEFKQKMQPLQVLEGDEVR 141

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIEN 1455
            +     ID   T K  +      I+N
Sbjct: 142  FDVR--IDGKPTPKVEWFKNRTKIDN 165



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 130/630 (20%), Positives = 248/630 (39%), Gaps = 105/630 (16%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            PE++   AA   + +G+ + +  Q+  K  P++K  WY +GK L  G R  + +      
Sbjct: 1281 PEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVK--WYKDGKPLRDGPRTTIRA------ 1332

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLED 3030
                    RD  +Y CK  + + E    + +Y     N +      K T   +    ++ 
Sbjct: 1333 --------RDD-LYNCKVLSAKPE---DTGMYKCEATNAVG-----KATRTFD----VQV 1371

Query: 3031 SLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090
             + K  G +P  +    P         V ++ G+       +  +G     I+W  + K 
Sbjct: 1372 EVPKPRGSKPSLEAELKP---------VTVTAGEDTKLVCKI--SGKPQPKIDWMKDDKP 1420

Query: 3091 IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPR 3150
            ++   R+   Y     VL        D   Y   A N+ G   +S   E +   KG  P+
Sbjct: 1421 LKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGS--VSTSAELLVNEKGAAPK 1478

Query: 3151 FTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFG-FVVL 3209
                +Q+++ +  G+ A F   V     P+  +EW+  G+ +        V D G F+++
Sbjct: 1479 IEKPLQDVK-VDAGKKATFNTQVSGTPTPE--VEWF-KGESI--------VEDKGRFMII 1526

Query: 3210 DIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269
            D       D+ E V +   +  +        C     V+ +  +  + AK+ ++++++ A
Sbjct: 1527 D-------DAKEGVFQLVIEDAKPEDSGVYKCV----VFNDIGETQTKAKL-QVDAVEVA 1574

Query: 3270 QQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329
             +        E P  + + Q+V   V+ +  +          PD KV WF +   +    
Sbjct: 1575 PKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYV---------PD-KVLWFKDDTPVKTNT 1624

Query: 3330 RYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTK----ANLKCTSKENLIL-DS 3384
              +   +  +  L +     +++G Y C +T KLG   +       ++    +  I  D 
Sbjct: 1625 TRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDR 1684

Query: 3385 QLPRGMEGG-----LEKLQTLEDSMVRRKDTS-----------VEEEKGKAPVFTVPLSN 3428
             L      G     L+ +   +  + + K T+           +  EK   PV   PLSN
Sbjct: 1685 HLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAVKPVIVKPLSN 1744

Query: 3429 IENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFG---FVILEISPT 3485
            ++ + E     FE ++    +P  +V WY     L  G+ ++   D G   F ++ ++ +
Sbjct: 1745 LQ-VEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLI-VNDS 1800

Query: 3486 YPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
               DSG Y C A N  G+A++ A+++V G+
Sbjct: 1801 QRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 40/118 (33%), Positives = 57/118 (48%), Gaps = 8/118 (6%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F   ++  EV EG+ V L   L+    PT   EW  NG PV+  +R + ++D  Y  L
Sbjct: 1932 PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTL 1989

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
              L A  ED GTY C A N  G A + + + V  K          Q +  I+++E YE
Sbjct: 1990 KFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGMIRDIEGYE 2041



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 54/195 (27%), Positives = 77/195 (39%), Gaps = 9/195 (4%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G P   T +F   V I EG    Y      +G     I WF +   +   +R+   Y   
Sbjct: 2222 GVPSFITGLFP--VQIKEGD--KYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASYEGS 2277

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +  LE+   K +D+G Y C ATN  G    S   E   K K   P F   ++  EGL   
Sbjct: 2278 VSALELKEMKLSDAGLYKCTATNSQGSTSSSA--EVTIKRKDAIPTFVVGLKETEGL--- 2332

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +S+     V     P   +E+Y +   +  S R K + D     L I   +  D+G Y C
Sbjct: 2333 ESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKC 2392

Query: 3225 RAYNKYGEDFTRATI 3239
               N  G + + A I
Sbjct: 2393 VITNLLGVETSEAVI 2407



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 73/321 (22%), Positives = 125/321 (38%), Gaps = 23/321 (7%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY-AFGMVVLEILGT-KT 3115
            V + EG     +A +   G     ++WF   + +    R   V    G +   I+G  K 
Sbjct: 423  VTVLEGDEIRLDARV--GGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKP 480

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
             DSG Y C+ATN  G+A    +++  +      P F         L +      E  V  
Sbjct: 481  LDSGVYICQATNDTGKATAEAEIQIEELLVA--PEFAEEEATQLTLIEDDDMTLELHV-- 536

Query: 3176 VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
               P  ++ W  + +P+    RI         ++DI     +DSG Y C A NK G + T
Sbjct: 537  TGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVN-T 595

Query: 3236 RATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLV 3295
            R  I       V +E L    ++++  + S++         P+ E P+    +Q++ +L 
Sbjct: 596  RTFI-------VNVEVLFVAGISQV--IGSIRFI--VLAKKPAGEAPEITESLQEMEEL- 643

Query: 3296 EGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEY 3355
            EG       +      P    EWF     +  G RY+         L I     +++ EY
Sbjct: 644  EGNPVTLTCKFTGTPAP--VAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEY 701

Query: 3356 ECVATNKLGRDSTKANLKCTS 3376
            + V  N +G   ++  ++ T+
Sbjct: 702  QVVIRNDIGSVKSETRVRITA 722



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 61/225 (27%), Positives = 89/225 (39%), Gaps = 36/225 (16%)

Query: 1978 PQF-GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            P+F G       V +G  + + A +T    P   V+WY +G+P++ G R           
Sbjct: 1281 PEFVGDQAAPIVVRQGEDIDIGAQITA--KPKPNVKWYKDGKPLRDGPRTTIRARDDLYN 1338

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096
              +L A  EDTG Y C+ATNAVG+A  T  V+V                    E+ K   
Sbjct: 1339 CKVLSAKPEDTGMYKCEATNAVGKATRTFDVQV--------------------EVPKPRG 1378

Query: 2097 PKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156
             KP  E +   +PV +TA         G+     C++     P   IDW  + + ++   
Sbjct: 1379 SKPSLEAE--LKPVTVTA---------GEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDK 1425

Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            R   T+D     L       ED   Y   A N+LG    +  L V
Sbjct: 1426 RVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLV 1470



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 77/312 (24%), Positives = 126/312 (40%), Gaps = 41/312 (13%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF--GYV 2035
            P+  KP+++ +V  G        ++    PT  VEW+     V+   RF    D   G  
Sbjct: 1477 PKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVF 1534

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDA-----KSGLYLDTLDEQ-RLKKIQ 2089
             L I  A  ED+G Y C   N +GE  T + ++VDA     K+   LD  +E   + + Q
Sbjct: 1535 QLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQ 1594

Query: 2090 ELE-------KYERPKPI--EEEQPGQ----RPVFLTA---LTSLENLKEGDRAHFECRV 2133
            E++       KY   K +  +++ P +    R +         +L +    D  H+ C  
Sbjct: 1595 EVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCES 1654

Query: 2134 EPINDPHLT-------IDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186
                   ++       ++W  + + I      +     G   L + +   +D G Y CK 
Sbjct: 1655 TTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKV 1714

Query: 2187 TNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHS-TRIEVEEPKISPPRFV 2245
            TNKLG A  TC   +  +   +     P  ++ +  L+ +  S TR EV+      PR V
Sbjct: 1715 TNKLGSA--TCGANLIVNEKAV----KPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPR-V 1767

Query: 2246 TELRGTTHVFEG 2257
                GTT + EG
Sbjct: 1768 AWYHGTTKLIEG 1779



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 4/129 (3%)

Query: 1812 SQHESALQKIQQLEDSSRYQRREDVEVAVN-QAPRFITQLNGPTKLSEGQSAHYECRIEP 1870
            S ++S + +           R  DV V V+ +APRF+++L  P ++ EG      C++  
Sbjct: 1899 SLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGKAPRFVSELR-PVEVFEGNEVSLVCKLSA 1957

Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
               P    EW  NG  ++  +R + S D  ++ L  L    ED G Y+C A N  G A S
Sbjct: 1958 EAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASS 2015

Query: 1931 SIRLNVQSK 1939
              +L V+ K
Sbjct: 2016 QAKLLVKKK 2024



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 7/118 (5%)

Query: 1742 LRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
            ++VEWL++  PI     L      G   L +K+V  +D G Y C+  N+LG A   + L 
Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728

Query: 1802 VQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
            V  KA   +       ++ +  L+   +   R +V++A N  PR +   +G TKL EG
Sbjct: 1729 VNEKAVKPV------IVKPLSNLQVEEKSLTRFEVQIAGNPKPR-VAWYHGTTKLIEG 1779



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 71/315 (22%), Positives = 118/315 (37%), Gaps = 16/315 (5%)

Query: 67   GEPSPPIF-EQIFKNARFAQGGN-AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
            G P  P F E   K+A + +GG        + G PTP V W +    L E     ++   
Sbjct: 1829 GRPCAPTFVEDEVKDAVYVRGGQEVSLMLTINGFPTPDVMWYKDDKELQESQL--VKIIP 1886

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEA--ICSVYIQPEGXXXXXXXXXXXXXYRHV 182
            +     L+I +    D G Y C A+N +G       V ++ +G                 
Sbjct: 1887 KGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGKAPRFVSELRPVEVFEG 1946

Query: 183  SE-TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESIT 241
            +E ++  K       T E SR    V   N    S    +    F    + +      + 
Sbjct: 1947 NEVSLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLA 2006

Query: 242  KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFK 301
            K   G +  Q    + +     + P+     R+ +  EG  A+F V  +GN  P+V W  
Sbjct: 2007 KNVFGSASSQAKLLVKKK---GNRPQPIGMIRDIEGYEGGQARFDVHFTGN--PKVEWLH 2061

Query: 302  NGQRLINSNKHEIITTHNH--TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP- 358
              +++I+  K++I         +L V + +  D G YT +A N +G       L V+   
Sbjct: 2062 GEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDKH 2121

Query: 359  -TESYVQDQRSQYIT 372
                +V+D   + IT
Sbjct: 2122 IAPMFVEDDTGEPIT 2136



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 46/218 (21%), Positives = 90/218 (41%), Gaps = 11/218 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            + W+ +G  ++ + R+     +    L +      D+G Y C A NK G A  +V ++ V
Sbjct: 2157 VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVK-V 2215

Query: 3142 DKSKGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            ++ KG+  P F T +  ++ +K+G      C V     P   I W+ +  P+    R+  
Sbjct: 2216 EELKGRGVPSFITGLFPVQ-IKEGDKYTLVCRV--SGKPKPTITWFRDNTPVHTDNRVVA 2272

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260
              +     L++   +  D+G Y C A N  G   + A +    K  +      P  +  +
Sbjct: 2273 SYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI------PTFVVGL 2326

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQ 3298
            +E E L+ +  +        P   +   +D   +V+ +
Sbjct: 2327 KETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSE 2364



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G  P F   L  +  ++EG+R   + RV+    P  T++W  +G+K++  HR +TT D  
Sbjct: 24   GTIPEFTKKLQPV-TVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGE 80

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               L I+ +  +D G Y C ATN++G+A  T  + V
Sbjct: 81   RCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLV 116



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 80/319 (25%), Positives = 127/319 (39%), Gaps = 47/319 (14%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            + EG  L L  +V  K  P++K  W  + K +++  R   T+      L L D    DSG
Sbjct: 230  ITEGDELDLSVRVRGKPKPEIK--WTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSG 287

Query: 2983 IYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDD 3042
             Y                  CT+K      ++H  GT   E   N+E +  K        
Sbjct: 288  RYK-----------------CTAK------SEH--GTASKEFDVNVEKAKPK-------- 314

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
              G  P+FT   + + +I E + A  E ++  TG+ +   EW    + ++ + RI+    
Sbjct: 315  --GVAPKFTKPLETL-EIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERD 369

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
               VVLE+   +  D   Y   A N+ G A  + + E +     +KP F    QN+  L 
Sbjct: 370  KDSVVLEVRHVELDDEALYKVVAKNESGVA--TSEAELLVNEATEKPFFKKTPQNVTVL- 426

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--FGFVVLDIAYTQNHDSG 3220
            +G     +  V     P+  ++W+   Q +    R   V D       L I   +  DSG
Sbjct: 427  EGDEIRLDARV--GGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSG 484

Query: 3221 EYVCRAYNKYGEDFTRATI 3239
             Y+C+A N  G+    A I
Sbjct: 485  VYICQATNDTGKATAEAEI 503



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 3/98 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP   + L+  + + EG+   LE +V     P   IEWFK+   +TT  R+++ +D   
Sbjct: 921  EAPSLVSELQPQE-ISEGEDAKLECKVSGEPQPT--IEWFKDDEPVTTDNRVRADYDGKT 977

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             TL+I     DD G Y C ATN LG   +T  + + ++
Sbjct: 978  STLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEK 1015



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 44/156 (28%), Positives = 65/156 (41%), Gaps = 11/156 (7%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            EV  +AP F   ++ + V E        +L     P    EW RNG P+   NR+    D
Sbjct: 1926 EVDGKAPRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFD 1983

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824
              Y  L       ED GTY+C A N  G A + + L V+ K +          +  I+ +
Sbjct: 1984 GRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGMIRDI 2037

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQ 1860
            E     Q R DV    N  P+ +  L+G  ++  G+
Sbjct: 2038 EGYEGGQARFDVHFTGN--PK-VEWLHGEEQIIHGE 2070



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 7/133 (5%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            P+    PEF   ++  ++++EG     +AR++  G  T  VEW+ DG  V+   RI T F
Sbjct: 21   PDKGTIPEFTKKLQP-VTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTF 77

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            +     L I      D G Y C A N +GQAT +   T V  K+ + + +    ++ +Q 
Sbjct: 78   DGERCTLKIMPSERDDEGEYKCVATNEVGQATIT---TEVLVKETLRKPEFKQKMQPLQV 134

Query: 1023 LE-DASRYSKRTE 1034
            LE D  R+  R +
Sbjct: 135  LEGDEVRFDVRID 147



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 4/116 (3%)

Query: 1295 ARRTKQVR-EDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI 1353
            A RT  V+ E++     P F   L  ++  EG    L CR+   G     + WF +  P+
Sbjct: 2207 ASRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPV 2264

Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409
             T +R   +YE    AL+L  +   D+G+Y C ATN  G + +S A   I +KD I
Sbjct: 2265 HTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQG-STSSSAEVTIKRKDAI 2319



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 8/115 (6%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F   L+ VT  EG +I  + R++  G PT  +EW+ +G+ ++   R  + F     +L
Sbjct: 27  PEFTKKLQPVTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751
            ++     D GEY C A +  G A       +T    ++ T + PE  Q +Q L+
Sbjct: 85  KIMPSERDDEGEYKCVATNEVGQAT------ITTEVLVKETLRKPEFKQKMQPLQ 133



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 3/95 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  L+    + EG+ + L+A+V+ +  P   +EW  +G  +    R+K+TFD    T
Sbjct: 27   PEFTKKLQPVT-VREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCT 83

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            L I     DD G Y C ATN +G+A  T  + +++
Sbjct: 84   LKIMPSERDDEGEYKCVATNEVGQATITTEVLVKE 118



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474
            +KG  P FT  L  +  +REGE    +AR+     P   VEW  +G+ ++   R +T  D
Sbjct: 22   DKGTIPEFTKKLQPV-TVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFD 78

Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
                 L+I P+  +D GEY C A N  G+A  T  + V+
Sbjct: 79   GERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVK 117



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 56/241 (23%), Positives = 96/241 (39%), Gaps = 18/241 (7%)

Query: 1164 EPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG 1223
            E   QIEE+  + P F +  +    + E  ++ LE  L   G P   V W  + + +T  
Sbjct: 500  EAEIQIEELLVA-PEFAEEEATQLTLIEDDDMTLE--LHVTGKPKPEVHWTKDNKPLTED 556

Query: 1224 SRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
             R    +      +DI+  T  D+G Y   A N  G    + IV V    +++      Q
Sbjct: 557  DRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNV----EVLFVAGISQ 612

Query: 1284 AIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMR 1343
             I  I+ +  A +            +AP+ + +L  +E +EG  V L C+    G     
Sbjct: 613  VIGSIRFIVLAKK---------PAGEAPEITESLQEMEELEGNPVTLTCKF--TGTPAPV 661

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             EWF    P++ G R++     +   L +     +D+  Y     N +G   +   +R+ 
Sbjct: 662  AEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRIT 721

Query: 1404 A 1404
            A
Sbjct: 722  A 722



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 8/117 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+F+  L+ V   EG ++    ++     PT   EW +NG  +   +R  + F   Y +L
Sbjct: 1932 PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTL 1989

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753
              L+  I+D G Y+C A +  G A ++A L       +++    P+ +  I+ +E Y
Sbjct: 1990 KFLNAKIEDQGTYSCLAKNVFGSASSQAKL------LVKKKGNRPQPIGMIRDIEGY 2040



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PRFV+  + +E V EG  V   CKL    ++    EW +NG PV + +R +   D  Y  
Sbjct: 1932 PRFVSELRPVE-VFEGNEVSLVCKLS--AEAKPTFEWSRNGSPVRLDNRVQASFDGRYST 1988

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            L  ++   ED G Y+C A N+ G+     +L
Sbjct: 1989 LKFLNAKIEDQGTYSCLAKNVFGSASSQAKL 2019



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 102/439 (23%), Positives = 167/439 (38%), Gaps = 42/439 (9%)

Query: 3373 KCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENL 3432
            +CT K   I+ S+  R  EG  + + T E          + +E  + P F   +  ++ L
Sbjct: 81   RCTLK---IMPSE--RDDEGEYKCVATNEVGQATITTEVLVKETLRKPEFKQKMQPLQVL 135

Query: 3433 REGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGE 3492
             EG+   F+ R+     P  KVEW+ N   +    RF    +     L I  T   D+  
Sbjct: 136  -EGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADT 192

Query: 3493 YLCRAYNNYGEAVTTASMKVQGKRNI--ILESQLPKGM-EGT-IDKIAALEGYSGTVDTL 3548
            Y C A +  G++     + V+ K +   +     P  + EG  +D    + G        
Sbjct: 193  YKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINITEGDELDLSVRVRGKPKPEIKW 252

Query: 3549 TPEAESGNPPE-FTTTPSD----LILSE---NSSAHFECRLIPVNDSSMRVEWFHNGKPL 3600
            T + +     +  TTT  D    L+LS+     S  ++C     + ++ +    +  K  
Sbjct: 253  TKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAK 312

Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK--LQVKGRQGIILE 3658
              G   K         LE   + +++     C  T      T   K    +K  Q I +E
Sbjct: 313  PKGVAPKFTKP-----LETLEIMEKETARLECTVTGEPAPTTEWLKGDQPLKETQRIKIE 367

Query: 3659 PQLPS------HFKSGTESIQKL----EETLHKREEITIEDEKPNPPRFTVEIKDNIDVP 3708
                S      H +   E++ K+    E  +   E   + +E    P F  +   N+ V 
Sbjct: 368  RDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFK-KTPQNVTVL 426

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF--GFIALDIDYIYARDAG 3766
            EG  +  D RV    +PT  +DWF   +  A   R   ++D      +L I      D+G
Sbjct: 427  EGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSG 484

Query: 3767 EYTCRATNKWGSATTTAKI 3785
             Y C+ATN  G AT  A+I
Sbjct: 485  VYICQATNDTGKATAEAEI 503



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 76/349 (21%), Positives = 135/349 (38%), Gaps = 22/349 (6%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+F  +++   V E + VRF+ R++ K  PK  +EW++N   + +  R+  + +    SL
Sbjct: 123  PEFKQKMQPLQVLEGDEVRFDVRIDGKPTPK--VEWFKNRTKIDNEGRFEIIDEEDLYSL 180

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI--ILQNQVPRGMKRSEALTQME 3947
             I      D+  Y C A ++ G+      +S K+      +  +  P  +   + L    
Sbjct: 181  IIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINITEGDELDLSV 240

Query: 3948 ATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTK------FECQLAPVG 4001
                K   E+  T+D   D   K+  R  T  +    ++ +   K      ++C  A   
Sbjct: 241  RVRGKPKPEIKWTKD---DKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKC-TAKSE 296

Query: 4002 DPNMKVEWFFN---GKPLLHKNRFT-PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG-- 4055
                  E+  N    KP     +FT P+     +      +    +GE       L G  
Sbjct: 297  HGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKETARLECTVTGEPAPTTEWLKGDQ 356

Query: 4056 -MDETKAVIKTTGKPGIVYD-SQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVF 4113
             + ET+ +     K  +V +   +    +++ K+     S   T E  +  ++A   P F
Sbjct: 357  PLKETQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFF 416

Query: 4114 VSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
               P  VTV EG+  R   RV G P+P V W      +    R+ +  D
Sbjct: 417  KKTPQNVTVLEGDEIRLDARVGGKPEPTVDWFKGDQKVAEEGRFLIVDD 465



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 49/199 (24%), Positives = 78/199 (39%), Gaps = 16/199 (8%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK  V W ++  P+   +R+   H      +++  V P DSGTY C A N+ G  V +
Sbjct: 538  GKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAG--VNT 595

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857
             T  V  +            +  I Q+  S R+      +    +AP     L    +L 
Sbjct: 596  RTFIVNVEVLF---------VAGISQVIGSIRFIVL--AKKPAGEAPEITESLQEMEEL- 643

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG      C+    P P    EW+     ++ G RY+ +       L I     +D+ EY
Sbjct: 644  EGNPVTLTCKFTGTPAP--VAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEY 701

Query: 1918 TCKAINNLGQAVSSIRLNV 1936
                 N++G   S  R+ +
Sbjct: 702  QVVIRNDIGSVKSETRVRI 720



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 3/119 (2%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            +P F K +K  EV EG    L+  +  V  PT  VEW+C    +    R++   +     
Sbjct: 725  RPDFTKKLKPVEVEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYT 782

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
            L I     +D  TY C A+N VG+      +KV  K     +    +R +KI  LEK E
Sbjct: 783  LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKM-FPPEITRPERTEKIVLLEKEE 840



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 36/106 (33%), Positives = 50/106 (47%), Gaps = 4/106 (3%)

Query: 2097 PKPIEEEQP-GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            P  +E+ +P G+ P  + AL  LE L EGD A   C++     P  T++WF    K+   
Sbjct: 1077 PITLEDMKPTGEAPKVVDALQPLEAL-EGDEAKLVCKIT--GSPTPTVEWFKEKAKVVDV 1133

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             R +  +      L I  T  ED G Y C A N  GEA  + TL +
Sbjct: 1134 RRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHI 1179



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 70/294 (23%), Positives = 117/294 (39%), Gaps = 40/294 (13%)

Query: 2196 TCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVF 2255
            TC L    H+ ++ D      + K  +L +   S  + V E K + P+    L+    V 
Sbjct: 1435 TCVLTF--HKAVLEDEAEYKVVAK-NELGSVSTSAELLVNE-KGAAPKIEKPLQDVK-VD 1489

Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF--GYVSLDIQHCVPEDAG 2313
             GK A F  QV     P   +E++     ++   RF I  D   G   L I+   PED+G
Sbjct: 1490 AGKKATFNTQVSGTPTPE--VEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSG 1547

Query: 2314 EYSVKAINALGHCTSAISMTVTA------KGSIISESQRPEGLEKIRELESAEPFKRPEI 2367
             Y     N +G   +   + V A          + E + P  + + +E++ +   K   +
Sbjct: 1548 VYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYV 1607

Query: 2368 PEPVT---RQRPVFTQPLQNIDNIQEGQ-------------TAHFDCRLIPVGDPTL--- 2408
            P+ V       PV T   + I +  EG+               H+ C        T+   
Sbjct: 1608 PDKVLWFKDDTPVKTNTTRKIHS--EGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTF 1665

Query: 2409 ----KVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                KVEW +++K I     + +    G  ++ + HV  +D+GVY C+ +N LG
Sbjct: 1666 LIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLG 1719



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 58/243 (23%), Positives = 95/243 (39%), Gaps = 32/243 (13%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++E Q V +  +V+ +  P+ K+ WFK+   + T    K   +  +  L++     DD+G
Sbjct: 1590 VLEHQEVDMSVKVKGKYVPD-KVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAG 1648

Query: 2714 IYTCKATNLLGEAVST--ASIKIE----------DRHWLLGESLHPDSLDRI-------- 2753
             Y C++T  LG  +ST    +K+E          DRH  L E+ H      I        
Sbjct: 1649 HYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRH--LKEAFHNGVCTLILKHVVQQD 1706

Query: 2754 -GALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFE------CNVEPSRDPTLK 2806
             G                    V    +  ++ K   N+  E        V+ + +P  +
Sbjct: 1707 KGVYKCKVTNKLGSATCGANLIVNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPR 1766

Query: 2807 IEWFFNNKPLPSGTRYKSTHDFS--YVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            + W+     L  GT YK   D      +L +  +   DSG+Y C A N  G A +  +L 
Sbjct: 1767 VAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLE 1826

Query: 2865 CTG 2867
             TG
Sbjct: 1827 VTG 1829



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 42/130 (32%), Positives = 60/130 (46%), Gaps = 12/130 (9%)

Query: 2231 RIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAAR 2290
            R+EV+      PRFV+ELR    VFEG      C++     P    E+  NG  ++   R
Sbjct: 1924 RVEVDG---KAPRFVSELR-PVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNR 1977

Query: 2291 FHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350
               +FD  Y +L   +   ED G YS  A N  G  +S   + V  KG+      RP+ +
Sbjct: 1978 VQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPI 2031

Query: 2351 EKIRELESAE 2360
              IR++E  E
Sbjct: 2032 GMIRDIEGYE 2041



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 2/89 (2%)

Query: 3824 PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            P   T P+F  +++  TV E E +  + RV+ K  P   +EW  +G+ +   HR +T +D
Sbjct: 21   PDKGTIPEFTKKLQPVTVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFD 78

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
                +L I+    +D GEY C A N+ G+
Sbjct: 79   GERCTLKIMPSERDDEGEYKCVATNEVGQ 107



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 37/126 (29%), Positives = 64/126 (50%), Gaps = 6/126 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P FT  ++ + V E +    +AR+   G P   VEW+ +G  ++  +R+ T  D     L
Sbjct: 27   PEFTKKLQPVTVREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE-DSSR 1829
             +     +D G Y C A NE+G+A  ++ + V  K +L+ + + +  +Q +Q LE D  R
Sbjct: 85   KIMPSERDDEGEYKCVATNEVGQATITTEVLV--KETLR-KPEFKQKMQPLQVLEGDEVR 141

Query: 1830 YQRRED 1835
            +  R D
Sbjct: 142  FDVRID 147



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 40/136 (29%), Positives = 59/136 (43%), Gaps = 10/136 (7%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            +  E  G+ P F++ L  +E + EG+     C++     P  T +W  NG  +R  +R +
Sbjct: 1923 VRVEVDGKAPRFVSELRPVE-VFEGNEVSLVCKLSAEAKP--TFEWSRNGSPVRLDNRVQ 1979

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEK 2219
             + D  Y  L  L    ED GTY C A N  G A +   L V    N       P  +  
Sbjct: 1980 ASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGM 2033

Query: 2220 IRQLEA-QGHSTRIEV 2234
            IR +E  +G   R +V
Sbjct: 2034 IRDIEGYEGGQARFDV 2049



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 6/143 (4%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P   + ++ Q  I EG  A  E ++   G+    +EW KD  PV   +R+   ++   
Sbjct: 921  EAPSLVSELQPQ-EISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTDNRVRADYDGKT 977

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDA 1026
              LTI+  T+ D G Y C A N +G  +TSA   ++  +  + E + P    K++  E  
Sbjct: 978  STLTIRDATLDDEGDYKCVATNELG--STSATTELLVNEKPVEEEKQP-EKPKVEKPEVE 1034

Query: 1027 SRYSKRTEEEVKITQKPRFLGPL 1049
                ++ E E  ++ KP    P+
Sbjct: 1035 EPEVEKPEVEEPVSGKPEVETPV 1057



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 72/309 (23%), Positives = 115/309 (37%), Gaps = 47/309 (15%)

Query: 3409 DTSVE--EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            D  +E  + KG+AP     L   E + EGE+A  E +++   +P   +EW+ + + +   
Sbjct: 910  DVQIEASKPKGEAPSLVSELQPQE-ISEGEDAKLECKVS--GEPQPTIEWFKDDEPVTTD 966

Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV------QGKRNIIL 3520
            +R R   D     L I     +D G+Y C A N  G    T  + V      + K+    
Sbjct: 967  NRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPVEEEKQPEKP 1026

Query: 3521 ESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAE--------------------------S 3554
            + + P+  E  ++K    E  SG  +  TP  E                          +
Sbjct: 1027 KVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDMKPT 1086

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G  P+       L   E   A   C++      +  VEWF     ++   R K       
Sbjct: 1087 GEAPKVVDALQPLEALEGDEAKLVCKI--TGSPTPTVEWFKEKAKVVDVRRTKMEYTDDV 1144

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQK 3674
              L I      D G+Y C A N  GEA+ S  L +         P +   FK+  + ++ 
Sbjct: 1145 ATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHI--------NPVVKPDFKTKLKPMEV 1196

Query: 3675 LEETLHKRE 3683
             EE++ K E
Sbjct: 1197 TEESVAKFE 1205



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 91/415 (21%), Positives = 155/415 (37%), Gaps = 79/415 (19%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F+  L   T+  E      + +I  +P P   VE+Y +  ++    R++   D    +
Sbjct: 2320 PTFVVGLK-ETEGLESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSR 1963
            L I  +  ED+G Y C   N LG         V++ E++IR  + E A            
Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLG---------VETSEAVIRVQEREHA------------ 2415

Query: 1964 YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023
                          P+F        VT      L  T      P   V W  +G  +   
Sbjct: 2416 --------------PRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSS 2461

Query: 2024 HRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQ 2083
            +           +L I+    ED+G Y C+A +++G+A  +  +                
Sbjct: 2462 NGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDL---------------- 2505

Query: 2084 RLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTI 2143
                     K E PK ++EE P     FL+ L  L+ ++EG    F+   + +      I
Sbjct: 2506 ---------KVEAPK-VKEEPPS----FLSELPPLQ-VREG--FEFKLIFKVVTTKDSKI 2548

Query: 2144 DWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
            +W  +G+    G     + D   + L       +D+G Y C  TNK GE+ ++  +    
Sbjct: 2549 EWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADI---- 2604

Query: 2204 HRNIILDTQHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRFVTELRGTTHVFEG 2257
              +I   T+ P  +  ++ +E+ +G   R +VE      P+ V    G T +  G
Sbjct: 2605 --SITQKTRKPEAIAPLKSIESVEGGQARFDVEMSAFPLPK-VDWYHGGTKITHG 2656



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP FT P++ + + E + A  E  +   G+P    EWL+   P++ + R+    D   V 
Sbjct: 317  APKFTKPLETLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVV 374

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            L +++V  +D   Y   A NE G A + + L V
Sbjct: 375  LEVRHVELDDEALYKVVAKNESGVATSEAELLV 407



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 49/212 (23%), Positives = 86/212 (40%), Gaps = 20/212 (9%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P F  +  +Q +L+E +    E  +   G P  +V W  + KPL   +R    +      
Sbjct: 512  PEFAEEEATQLTLIEDDDMTLELHVT--GKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCI 569

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA 4092
            ++   V P DSG Y C A N  G++    ++       +++ + + + + SI  I     
Sbjct: 570  VDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVE----VLFVAGISQVIGSIRFI----- 620

Query: 4093 SWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIV 4152
                    + ++     P +  SL +   + EG      C+ TG P P   W      + 
Sbjct: 621  -------VLAKKPAGEAPEITESLQEMEEL-EGNPVTLTCKFTGTPAPVAEWFKASTPVR 672

Query: 4153 NGSRYKL-TYDGMYHFDIPKTRQYDTGKIEVI 4183
            +G RYK+ T D      I +TR  D  + +V+
Sbjct: 673  DGRRYKITTTDNTTTLTIKETRLDDNTEYQVV 704



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 58/247 (23%), Positives = 99/247 (40%), Gaps = 31/247 (12%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+  + L +++   G       ++   G  T  VEWF     ++   RF    +     
Sbjct: 1476 APKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533

Query: 1370 LDLL--SVYPEDSGVYTCQATNQLGEAVTSCALRVIA-----KKDLIL-ESQHPSGLEKI 1421
              L+     PEDSGVY C   N +GE  T   L+V A     K D  L E + P  + + 
Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEH 1593

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENV-IEGQHV-------------HFEC- 1466
            Q ++ + + K   + D+ +  K     +  +   +  EG+               H+ C 
Sbjct: 1594 QEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCE 1653

Query: 1467 ---KLEPVTDSNL---KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCR 1520
               KL     + L   KVEW K+ +P+      +     G   L +  ++ +D G+Y C+
Sbjct: 1654 STTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCK 1713

Query: 1521 AVNLVGT 1527
              N +G+
Sbjct: 1714 VTNKLGS 1720



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 5/86 (5%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF--GY 2433
            P   +PLQ++  +  G+ A F+ ++   G PT +VEWF+ E ++ED  R     D   G 
Sbjct: 1477 PKIEKPLQDV-KVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
              + I   + ED GVY C   N +GE
Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGE 1559



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 3/84 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+F  ++Q VT + EG+    +AR+     P   VEW  +G+K+   HR +T  D     
Sbjct: 27   PEFTKKLQPVT-VREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCT 83

Query: 3342 LDILYCYEENSGEYECVATNKLGR 3365
            L I+    ++ GEY+CVATN++G+
Sbjct: 84   LKIMPSERDDEGEYKCVATNEVGQ 107



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 7/137 (5%)

Query: 1138 RSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHL 1197
            ++S++ S I+R + + T H   S+  +      E+    P FV  L  P  V EG  + L
Sbjct: 1897 KASLNDSGIYRCVAKNT-HGSVSRTFDVRV---EVDGKAPRFVSEL-RPVEVFEGNEVSL 1951

Query: 1198 ECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNH 1257
             C+L     PT   EW  NG  V + +R +  +D  +  L  ++A   D G Y+  A N 
Sbjct: 1952 VCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNV 2009

Query: 1258 LGSAHTSAIVRVIERSD 1274
             GSA + A + V ++ +
Sbjct: 2010 FGSASSQAKLLVKKKGN 2026



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 3/111 (2%)

Query: 764  EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
            E   + P+F+  L+ + E+ EG       +L+  + PT   EW ++G P+   +R+ + F
Sbjct: 1926 EVDGKAPRFVSELRPV-EVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASF 1982

Query: 824  NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874
            +  Y +L  ++ + ED G+Y+  A N  G A S A + V  +      +G+
Sbjct: 1983 DGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGNRPQPIGM 2033



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 6/116 (5%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F + L  P  V EG+ I L+ R++  G PT  VEW  +G  V    R KT +D     
Sbjct: 27   PEFTKKLQ-PVTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCT 83

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLE 1292
            L I+ +   D GEY   A N +G A  +  V V    + +   + +Q ++ +Q+LE
Sbjct: 84   LKIMPSERDDEGEYKCVATNEVGQATITTEVLV---KETLRKPEFKQKMQPLQVLE 136



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            + + EG      CRV   G P   I WF +  P  T +RV    +    AL++  +   D
Sbjct: 2233 VQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSD 2290

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAK 3790
            AG Y C ATN  GS +++A++T   K
Sbjct: 2291 AGLYKCTATNSQGSTSSSAEVTIKRK 2316



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 35/107 (32%), Positives = 52/107 (48%), Gaps = 3/107 (2%)

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            R D  V+E K  AP F    +    +R+GE+    A++T    PN+K  WY +GK L+ G
Sbjct: 1269 RADLKVKE-KDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVK--WYKDGKPLRDG 1325

Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             R            ++    PED+G Y C A N  G+A  T  ++V+
Sbjct: 1326 PRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 87/388 (22%), Positives = 143/388 (36%), Gaps = 30/388 (7%)

Query: 1030 SKRTEEEVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
            S  T  E+ + +K   P+   PL+   K+  G+ A F  +V      T  VEW+     +
Sbjct: 1461 SVSTSAELLVNEKGAAPKIEKPLQDV-KVDAGKKATFNTQVSGTP--TPEVEWFKGESIV 1517

Query: 1087 TSANRIQTYHDF--GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTS 1144
                R     D   G   L I   + EDSGVY  V  N  GE Q  A + V+       +
Sbjct: 1518 EDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKT 1577

Query: 1145 SIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEG--KNIHLECRLE 1202
               + L EK   I   +  E    ++   K  P  V    +  PV     + IH E R+ 
Sbjct: 1578 D--KKLDEKEEPITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMY 1635

Query: 1203 --PMGDPTMRVEWFHNGRSVT-VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLG 1259
               + D ++     +   S T +G+   T+         II        +  +    HL 
Sbjct: 1636 YLTLTDASLDDAGHYRCESTTKLGTTISTFL--------IIVKVEWLKDDKPIAKDRHLK 1687

Query: 1260 SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHN 1319
             A  + +  +I +  +V   +     +    L  A      +  +  V   P   + L N
Sbjct: 1688 EAFHNGVCTLILK-HVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAV--KPVIVKPLSN 1744

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL--SVYP 1377
            ++  E +    E  +Q  G+   RV W+     +  G  ++   +       L+      
Sbjct: 1745 LQVEEKSLTRFE--VQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQR 1802

Query: 1378 EDSGVYTCQATNQLGEAVTSCALRVIAK 1405
             DSGVY C A N+ G+A++   L V  +
Sbjct: 1803 HDSGVYKCVAVNEAGKAISQATLEVTGR 1830



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 3/132 (2%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRT-DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERR 1600
            I +++ N++G+ +           RT D+  EV  +AP   + L+ VE+ EG       +
Sbjct: 1895 IYKASLNDSGIYRCVAKNTHGSVSRTFDVRVEVDGKAPRFVSELRPVEVFEGNEVSLVCK 1954

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            L   +  T   EW  N  P++  +R   + +  +  L  ++   ED GTY+C A N  G 
Sbjct: 1955 LSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGS 2012

Query: 1661 AVTSGIAIVHSK 1672
            A +    +V  K
Sbjct: 2013 ASSQAKLLVKKK 2024



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 15/152 (9%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+S L  +   EG+ +   C +     PT   EW  N  P+    R +++ D  Y +L  
Sbjct: 1934 FVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKF 1991

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
             +   ED G Y+C A N  GSA++   L      N       PQ    +  +E  E  + 
Sbjct: 1992 LNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN------RPQPIGMIRDIEGYEGGQ- 2044

Query: 2896 AKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQ 2927
                R  V  T  PK EW   +  E Q++ G+
Sbjct: 2045 ---ARFDVHFTGNPKVEW---LHGEEQIIHGE 2070



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 81/354 (22%), Positives = 137/354 (38%), Gaps = 58/354 (16%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPA--YEFD 1366
            + P F +   N+  +EG  + L+ R+    + T  V+WF   + +    RF      E D
Sbjct: 412  EKPFFKKTPQNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGD 469

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLED 1426
              +L + +  P DSGVY CQATN  G+A     +++   ++L++           ++ E+
Sbjct: 470  LFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI---EELLVAP---------EFAEE 517

Query: 1427 TSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP 1486
             +  + T I D+ +T++     +PK          VH+       T  N         +P
Sbjct: 518  EAT-QLTLIEDDDMTLELHVTGKPK--------PEVHW-------TKDN---------KP 552

Query: 1487 VTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVR-S 1545
            +T   R    H      +DI+ +   DSG Y C A N  G +         + T IV   
Sbjct: 553  LTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVN---------TRTFIVNVE 603

Query: 1546 TQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVS 1605
                AG+ Q+             +  +   +AP  T SL+ +E  EG       +     
Sbjct: 604  VLFVAGISQV-----IGSIRFIVLAKKPAGEAPEITESLQEMEELEGNPVTLTCKF--TG 656

Query: 1606 DATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
                  EW+  + P++ G R+  T       L I     +D+  Y     N +G
Sbjct: 657  TPAPVAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG 710



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 66/277 (23%), Positives = 104/277 (37%), Gaps = 38/277 (13%)

Query: 3542 SGTVDT-LTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL 3600
            S T+D  +      G  P   +      +SE   A  EC++    +    +EWF + +P+
Sbjct: 906  STTIDVQIEASKPKGEAPSLVSELQPQEISEGEDAKLECKVS--GEPQPTIEWFKDDEPV 963

Query: 3601 LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ-GIILEP 3659
             T +RV+   D     L I      D G Y C ATN  G  + + +L V  +      +P
Sbjct: 964  TTDNRVRADYDGKTSTLTIRDATLDDEGDYKCVATNELGSTSATTELLVNEKPVEEEKQP 1023

Query: 3660 QLPSHFKSGTE--SIQK--LEETLHKREE---------------ITIE----------DE 3690
            + P   K   E   ++K  +EE +  + E               +T+E          D 
Sbjct: 1024 EKPKVEKPEVEEPEVEKPEVEEPVSGKPEVETPVGEVPQEVLAPVTVEVVETAPITLEDM 1083

Query: 3691 KP--NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748
            KP    P+  V+    ++  EG      C++   G PT  ++WF          R     
Sbjct: 1084 KPTGEAPK-VVDALQPLEALEGDEAKLVCKI--TGSPTPTVEWFKEKAKVVDVRRTKMEY 1140

Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                  L I      D G Y C A N +G A+T+A +
Sbjct: 1141 TDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATL 1177



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            PRF  E++  ++V EG  V   C++     PT   +W  NG P    +RV    D  +  
Sbjct: 1932 PRFVSELRP-VEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYST 1988

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            L        D G Y+C A N +GSA++ AK+    K
Sbjct: 1989 LKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK 2024



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 2/82 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F   ++ +  +EG ++ F+ RI+  G PT K+EW KN   I+   RF  I      SL
Sbjct: 123 PEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSL 180

Query: 697 DMLSLNIQDSGEYTCRAVSATG 718
            +    + D+  Y C A S  G
Sbjct: 181 IIDDTRLSDADTYKCIATSEAG 202



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 55/212 (25%), Positives = 90/212 (42%), Gaps = 37/212 (17%)

Query: 1865 ECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFG--FAALDILTVYGEDSGEYTCKAI 1922
            + R + +   N +VEW    + +  G +Y+ S + G    +L +  +  ED G YTC A 
Sbjct: 2044 QARFDVHFTGNPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVAS 2103

Query: 1923 NNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGK 1982
            N  G A     LN       ++D +H + +    ++EDD+                  G+
Sbjct: 2104 NESGDATLHANLN-------VKD-KHIAPM----FVEDDT------------------GE 2133

Query: 1983 PIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYA 2042
            PI    V  G  +++   +    +P   V WY +G  +QQ  R   +  +    L +  A
Sbjct: 2134 PIT---VEAGKELNVIMNIR--GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKA 2188

Query: 2043 YAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074
              +D G Y C+A N +G A  T  VKV+   G
Sbjct: 2189 VPDDAGIYRCEAKNKLGTASRTVMVKVEELKG 2220



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 37/145 (25%), Positives = 69/145 (47%), Gaps = 11/145 (7%)

Query: 2218 EKIRQLEAQGHSTRIEVEEPKIS--PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLR 2275
            + +  L     S  ++VE PK+   PP F++EL     V EG    F+   + V   + +
Sbjct: 2491 QAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELP-PLQVREG--FEFKLIFKVVTTKDSK 2547

Query: 2276 IEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
            IE+  +G+A         +FD   ++L  ++   +DAG Y     N  G  +S+  +++T
Sbjct: 2548 IEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISIT 2607

Query: 2336 AKGSIISESQRPEGLEKIRELESAE 2360
             K      +++PE +  ++ +ES E
Sbjct: 2608 QK------TRKPEAIAPLKSIESVE 2626



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 12/161 (7%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            +K   P FT +++  + V EG  +  D RV+  G PT  ++W  +G       R+ T  D
Sbjct: 22   DKGTIPEFTKKLQP-VTVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFD 78

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809
                 L I      D GEY C ATN+ G AT T ++     ++ + + +  Q M   ++ 
Sbjct: 79   GERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLV---KETLRKPEFKQKMQPLQVL 135

Query: 3810 ELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850
            E +  R      +  I   P   +   K+ T  ++EG RFE
Sbjct: 136  EGDEVRF-----DVRIDGKPTPKVEWFKNRTKIDNEG-RFE 170



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 66/244 (27%), Positives = 98/244 (40%), Gaps = 44/244 (18%)

Query: 3409 DTSVEEEK--GKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            D +VE+ K  G AP FT PL  +E + E E A  E   T T +P    EW    + LK  
Sbjct: 305  DVNVEKAKPKGVAPKFTKPLETLE-IMEKETARLEC--TVTGEPAPTTEWLKGDQPLKET 361

Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPK 3526
             R +   D   V+LE+     +D   Y   A N  G A + A +       ++ E+    
Sbjct: 362  QRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAEL-------LVNEATEKP 414

Query: 3527 GMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVND 3586
              + T   +  LEG     D +  +A  G  PE T    D    +   A  E R + V+D
Sbjct: 415  FFKKTPQNVTVLEG-----DEIRLDARVGGKPEPTV---DWFKGDQKVAE-EGRFLIVDD 465

Query: 3587 SSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
                +                    F  +I   G     D+G+Y C+ATN  G+AT   +
Sbjct: 466  EEGDL--------------------FSLII---GNAKPLDSGVYICQATNDTGKATAEAE 502

Query: 3647 LQVK 3650
            +Q++
Sbjct: 503  IQIE 506



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            RP FT+ L+ ++ ++EGQ A  D R+  VG PT  VEWF     + D+ R     +    
Sbjct: 725  RPDFTKKLKPVE-VEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSY 781

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQ 2492
            ++ I     +D+  Y C ASN +G+                 E   PE  +KI  LE+
Sbjct: 782  TLIIKTTVRDDDDTYKCVASNQVGK-VTCRGDLKVTEKMFPPEITRPERTEKIVLLEK 838



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+F+++++   V E   V   C++  +  P    EW RNG  +   +R +  +D  + +L
Sbjct: 1932 PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTL 1989

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
              L    ED G Y C A N FG   ++A +  KK
Sbjct: 1990 KFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKK 2023



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 8/156 (5%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E+ +KPEFK  ++  + + EG    F+ R++  G  T +VEW K+   ++   R    
Sbjct: 116  VKETLRKPEFKQKMQP-LQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEII 172

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDI--IAESQHPGGLEK 1019
                  +L I    + DA  Y C A +  G++T    L++  K     +     P  + +
Sbjct: 173  DEEDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPINITE 232

Query: 1020 IQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKI 1055
               L+ + R   + + E+K T+  +   P+K T+++
Sbjct: 233  GDELDLSVRVRGKPKPEIKWTKDDK---PIKKTDRL 265



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT+PL+ ++ I E +TA  +C +   G+P    EW + ++ ++++ RI    D   V 
Sbjct: 318  PKFTKPLETLE-IMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVV 374

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + + HV  +DE +Y   A N  G
Sbjct: 375  LEVRHVELDDEALYKVVAKNESG 397



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 43/147 (29%), Positives = 68/147 (46%), Gaps = 6/147 (4%)

Query: 3395 EKLQTLEDSMVRRKDTSVEEEK--GKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNL 3452
            E L  +   +V     ++E+ K  G+AP     L  +E L EG+ A    ++T +  P  
Sbjct: 1063 EVLAPVTVEVVETAPITLEDMKPTGEAPKVVDALQPLEAL-EGDEAKLVCKITGSPTPT- 1120

Query: 3453 KVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
             VEW+     +    R +         L I  T PED G Y C A N++GEA T+A++ +
Sbjct: 1121 -VEWFKEKAKVVDVRRTKMEYTDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHI 1179

Query: 3513 QGKRNIILESQLPKGMEGTIDKIAALE 3539
                    +++L K ME T + +A  E
Sbjct: 1180 NPVVKPDFKTKL-KPMEVTEESVAKFE 1205



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 4/112 (3%)

Query: 1030 SKRTEEEVKITQK-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
            S+  +  V++  K PRF+  L+   ++ EG       ++  ++  T   EW  NG  +  
Sbjct: 1918 SRTFDVRVEVDGKAPRFVSELRPV-EVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRL 1974

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             NR+Q   D  Y  L   + + ED G Y+ +A+N  G A   A + V+ + +
Sbjct: 1975 DNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN 2026



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 3/102 (2%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            +EE +    P F+T L  ++ +KEGD+    CRV     P  TI WF +   +   +R  
Sbjct: 2215 VEELKGRGVPSFITGLFPVQ-IKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVV 2271

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             +++    AL++      D+G Y C ATN  G   ++  + +
Sbjct: 2272 ASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTI 2313



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 38/102 (37%), Positives = 50/102 (49%), Gaps = 7/102 (6%)

Query: 2104 QPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR---- 2159
            Q  ++P  +  L S+E++ EG +A F+  VE    P   +DW+H G KI  G RY+    
Sbjct: 2608 QKTRKPEAIAPLKSIESV-EGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQS 2664

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            T  D     L I      DSGTY C ATN+ G       LKV
Sbjct: 2665 TDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 53/193 (27%), Positives = 76/193 (39%), Gaps = 16/193 (8%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            V W  + K +T  +RI   H      +DI +V   DSG Y   A+N AG    +  + VE
Sbjct: 544  VHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVE 603

Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196
                   S +   +    R I  +K  +P  +  EI++S    +Q +       EG  + 
Sbjct: 604  VLFVAGISQVIGSI----RFIVLAK--KPAGEAPEITES----LQEMEE----LEGNPVT 649

Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256
            L C+    G P    EWF     V  G R+K         L I      D  EY V   N
Sbjct: 650  LTCKFT--GTPAPVAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRN 707

Query: 1257 HLGSAHTSAIVRV 1269
             +GS  +   VR+
Sbjct: 708  DIGSVKSETRVRI 720



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 3/106 (2%)

Query: 1833 REDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH 1891
            R D++V     AP F+     P  + +G+      +I   P PN  V+WY +GK L+ G 
Sbjct: 1269 RADLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPN--VKWYKDGKPLRDGP 1326

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            R             +L+   ED+G Y C+A N +G+A  +  + V+
Sbjct: 1327 RTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 83/381 (21%), Positives = 147/381 (38%), Gaps = 29/381 (7%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            E G  P+      D+ +     A F  ++      +  VEWF     +    R   I+D 
Sbjct: 1472 EKGAAPKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDA 1529

Query: 3613 --GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTE 3670
              G   L I      D+G+Y C   N  GE     KLQV     + + P+         E
Sbjct: 1530 KEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQV---DAVEVAPKTDKKLDEKEE 1586

Query: 3671 SIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEG--GPVHFDCRVEPVGDPTMR 3728
             I  LE   H+  +++++ +    P   +  KD+  V       +H + R+  +      
Sbjct: 1587 PITVLE---HQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDAS 1643

Query: 3729 IDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            +D   + R  +T     T++ F  I + ++++  +D  +           A      T  
Sbjct: 1644 LDDAGHYRCESTTKLGTTISTF-LIIVKVEWL--KD--DKPIAKDRHLKEAFHNGVCTLI 1698

Query: 3789 AKRDIVLESQLPQGMSGEKIKELERGR--ISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846
             K  +  +  + +     K+     G   I +    +P++  P      + +  VEE   
Sbjct: 1699 LKHVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAVKPVIVKP------LSNLQVEEKSL 1752

Query: 3847 VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAE--DSGEYIC 3904
             RFE  V+   +PK R+ WY     L  G  Y+ + D G  +  ++   ++  DSG Y C
Sbjct: 1753 TRFE--VQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKC 1810

Query: 3905 RAVNDFGEDFTKATISCKKLP 3925
             AVN+ G+  ++AT+     P
Sbjct: 1811 VAVNEAGKAISQATLEVTGRP 1831



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 3/98 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP F + L+  + + EG  V L  ++     P    EW +NG  +    R++++FD   
Sbjct: 1930 KAPRFVSELRPVE-VFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRY 1986

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             TL   + + +D G Y+C A N+ G A S A + ++ +
Sbjct: 1987 STLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK 2024



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 3/90 (3%)

Query: 919  ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
            + IKEG       R+   G     + W +D  PV   +R+   +     AL +K + + D
Sbjct: 2233 VQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSD 2290

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
            AG Y C A N+ G  ++SA +TI  +KD I
Sbjct: 2291 AGLYKCTATNSQGSTSSSAEVTI-KRKDAI 2319



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 36/128 (28%), Positives = 49/128 (38%), Gaps = 2/128 (1%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L  +   E +    EC V     PT   EW   ++PL    R K   D   V L++
Sbjct: 320  FTKPLETLEIMEKETARLECTVTGEPAPTT--EWLKGDQPLKETQRIKIERDKDSVVLEV 377

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARL 2895
             H   +D  +Y   A N  G AT+   L         F  + PQ    LE  E   +AR+
Sbjct: 378  RHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLEGDEIRLDARV 437

Query: 2896 AKGRRPSV 2903
                 P+V
Sbjct: 438  GGKPEPTV 445



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 1/97 (1%)

Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022
            DL   +K  PP  +T+ +    +V +E  +    +  +G+P   V+WF +GKP+   +R 
Sbjct: 812  DLKVTEKMFPPE-ITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRL 870

Query: 4023 TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDET 4059
                      +N     PED+G Y C A N  G   T
Sbjct: 871  NIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSST 907



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 3/88 (3%)

Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF 2431
            T ++P F Q +Q +  + EG    FD R+   G PT KVEWF+N   I++  R     + 
Sbjct: 119  TLRKPEFKQKMQPLQ-VLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEE 175

Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLGE 2459
               S+ I   R  D   Y C A++  G+
Sbjct: 176  DLYSLIIDDTRLSDADTYKCIATSEAGK 203



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 46/200 (23%), Positives = 81/200 (40%), Gaps = 36/200 (18%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595
            G+P     WY +G  L+   R   +  +    L +   V +DAG+Y C+A N+ G     
Sbjct: 2151 GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRT 2210

Query: 2596 XXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLV 2655
                                   ++++E     VP     TG     +F   +K  DK  
Sbjct: 2211 V---------------------MVKVEELKGRGVPSFI--TG-----LFPVQIKEGDKYT 2242

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
                  L  +V  +  P   I WF++   + T  R+ ++++  +  L +  ++  D+G+Y
Sbjct: 2243 ------LVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLY 2294

Query: 2716 TCKATNLLGEAVSTASIKIE 2735
             C ATN  G   S+A + I+
Sbjct: 2295 KCTATNSQGSTSSSAEVTIK 2314



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P+F + LQ +  ++EG     +A++     PT  VEW  DG  +    RI + F+    +
Sbjct: 27  PEFTKKLQPV-TVREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFDGERCT 83

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           L IM    +D G Y   A N++G+A  T  + V
Sbjct: 84  LKIMPSERDDEGEYKCVATNEVGQATITTEVLV 116



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 46/219 (21%), Positives = 84/219 (38%), Gaps = 18/219 (8%)

Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
           +T +E   +  E  +   G P  ++ W K+ + +    R     +     +D++++   D
Sbjct: 522 LTLIEDDDMTLELHV--TGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPND 579

Query: 706 SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQ 765
           SG Y C A +  GV     +++V     +   SQ   ++++I               ++ 
Sbjct: 580 SGTYKCEAKNKAGVNTRTFIVNVEV-LFVAGISQVIGSIRFI------------VLAKKP 626

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
             + P+    LQ++ EL EG       + T    P    EW+K   P+    R       
Sbjct: 627 AGEAPEITESLQEMEEL-EGNPVTLTCKFTGTPAPV--AEWFKASTPVRDGRRYKITTTD 683

Query: 826 GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
              +L I   R +D   Y V   N +G   S   +R+ A
Sbjct: 684 NTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITA 722



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 23/63 (36%), Positives = 37/63 (58%)

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            V+W+ +GKP++ G R       D     +LS  PED+G+Y C+ATN +G+A  +  ++V 
Sbjct: 1313 VKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372

Query: 1404 AKK 1406
              K
Sbjct: 1373 VPK 1375



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 59/289 (20%), Positives = 120/289 (41%), Gaps = 34/289 (11%)

Query: 1815 ESALQKIQQLEDSSRYQRREDVEV-AVNQAPRFITQLNG---PTKLSEGQSAHYECRIEP 1870
            +S + K     D    Q +  ++V AV  AP+   +L+    P  + E Q      +++ 
Sbjct: 1545 DSGVYKCVVFNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKG 1604

Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
               P+ +V W+ +   +++    +  ++     L +     +D+G Y C++   LG  +S
Sbjct: 1605 KYVPD-KVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTIS 1663

Query: 1931 SIRLNVQ----------SKESIIRDSQHESA---LEKIQYLEDDSRYKRAVQDD------ 1971
            +  + V+          +K+  ++++ H      + K    +D   YK  V +       
Sbjct: 1664 TFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATC 1723

Query: 1972 --SFVVE----KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR 2025
              + +V     KP   KP+ N +V E      E  +    +P  RV WY     + +G  
Sbjct: 1724 GANLIVNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTI 1781

Query: 2026 FKTTYDFGYVALDILY--AYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            +K   D G     ++   +   D+G Y C A N  G+A++ ++++V  +
Sbjct: 1782 YKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 3/99 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P FIT L  P ++ EG      CR+   P P   + W+ +   + + +R   S +   +A
Sbjct: 2224 PSFITGLF-PVQIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSA 2280

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            L++  +   D+G Y C A N+ G   SS  + ++ K++I
Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 10/152 (6%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P F + +   + ++EG    F+   + +     ++EW KDGR           F+   
Sbjct: 2515 EPPSFLSELPP-LQVREG--FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRN 2571

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDA 1026
            + L  K+ T+ DAG Y C   N  G++++SA+++I  K      ++ P  +  ++ +E  
Sbjct: 2572 ITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK------TRKPEAIAPLKSIESV 2625

Query: 1027 SRYSKRTEEEVKITQKPRFLGPLKGTNKIVEG 1058
                 R + E+     P+ +    G  KI  G
Sbjct: 2626 EGGQARFDVEMSAFPLPK-VDWYHGGTKITHG 2656



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 2/98 (2%)

Query: 4715 PDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG 4773
            PD+   +P  T  L+ + V EG+      ++  K  PT++W+ +G  + +    +   +G
Sbjct: 21   PDKG-TIPEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKVQDDHRIKTTFDG 79

Query: 4774 NNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                L I  +  +D G + C AT   GQ   + +++VK
Sbjct: 80   ERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVK 117



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L  +  +EG+ I  +  V+    PT  +EW  + + +    R K+T D    +L I
Sbjct: 29   FTKKLQPVTVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCTLKI 86

Query: 2836 THTYEEDSGIYTCKATNSKGSAT 2858
              +  +D G Y C ATN  G AT
Sbjct: 87   MPSERDDEGEYKCVATNEVGQAT 109



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F  +++  + V EG  V FD R++  G PT +++WF N        R   +++    +
Sbjct: 123  PEFKQKMQP-LQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYS 179

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            L ID     DA  Y C AT++ G +T   +++   K
Sbjct: 180  LIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEK 215



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F KP++  E+ E     LE T+T   +P    EW    +P+++  R K   D   V L
Sbjct: 318  PKFTKPLETLEIMEKETARLECTVT--GEPAPTTEWLKGDQPLKETQRIKIERDKDSVVL 375

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            ++ +   +D   Y   A N  G A + + + V+
Sbjct: 376  EVRHVELDDEALYKVVAKNESGVATSEAELLVN 408



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 58/260 (22%), Positives = 101/260 (38%), Gaps = 22/260 (8%)

Query: 1289 QLLEDAARRTKQVREDIT-VMQAPQFSRA-LHNIETVEGTNVHLECRLQPVGDQTMRVEW 1346
            Q   D  + T +    I  ++ AP+F+      +  +E  ++ LE  L   G     V W
Sbjct: 489  QATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLE--LHVTGKPKPEVHW 546

Query: 1347 FCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
              + KP+    R    ++ D   +D+++V P DSG Y C+A N+ G    +  + V    
Sbjct: 547  TKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNV---- 602

Query: 1407 DLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFEC 1466
                E    +G+ ++         +   +  +     P      + +E  +EG  V   C
Sbjct: 603  ----EVLFVAGISQV-----IGSIRFIVLAKKPAGEAPEITESLQEMEE-LEGNPVTLTC 652

Query: 1467 KLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            K    T + +  EWFK   PV  G R++         L I +   +D+  Y     N +G
Sbjct: 653  KFTG-TPAPV-AEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG 710

Query: 1527 T--DEVSCRLTCRSTTDIVR 1544
            +   E   R+T     D  +
Sbjct: 711  SVKSETRVRITALVRPDFTK 730



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 55/227 (24%), Positives = 91/227 (40%), Gaps = 38/227 (16%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            ++V+E K   P FV +      V +G+      Q+     PN  +++Y +GK L+   R 
Sbjct: 1272 LKVKE-KDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPN--VKWYKDGKPLRDGPRT 1328

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
             I       +  +    PED G Y  +A NA+G  T    + V        E  +P G  
Sbjct: 1329 TIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQV--------EVPKPRG-- 1378

Query: 2352 KIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVE 2411
                   ++P    E+ +PVT               +  G+     C++   G P  K++
Sbjct: 1379 -------SKPSLEAEL-KPVT---------------VTAGEDTKLVCKI--SGKPQPKID 1413

Query: 2412 WFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            W +++K ++   R+  T+D     +T      EDE  Y   A N LG
Sbjct: 1414 WMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELG 1460



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P+F+        +++G +    AQ+T  + P   V+WYKDG+P+    R T        +
Sbjct: 1281 PEFVGDQAAPIVVRQGEDIDIGAQIT--AKPKPNVKWYKDGKPLRDGPRTTIRARDDLYN 1338

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
              ++  + ED G Y   A N +G+A  T  ++V
Sbjct: 1339 CKVLSAKPEDTGMYKCEATNAVGKATRTFDVQV 1371



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 6/119 (5%)

Query: 3951 KKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWF 4010
            K     V  T D   +VD K P RFV++++    + E       C+L+    P    EW 
Sbjct: 1911 KNTHGSVSRTFDVRVEVDGKAP-RFVSELRP-VEVFEGNEVSLVCKLSAEAKPTF--EWS 1966

Query: 4011 FNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG--MDETKAVIKTTG 4067
             NG P+   NR    +D  Y  + F     ED G Y C A N++G    + K ++K  G
Sbjct: 1967 RNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKG 2025



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 38/203 (18%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK  + W R+  P+   NR+   ++    AL +K +   D+G Y C A N  G   +S
Sbjct: 2249 GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSS 2308

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857
            + + ++ K ++         L++ + LE S        ++V +   PR       PT   
Sbjct: 2309 AEVTIKRKDAI---PTFVVGLKETEGLESSDM-----RLDVKIGGFPR-------PT--- 2350

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
                      +E Y D ++ V+     K+L+ G R          +L I  +  ED+G Y
Sbjct: 2351 ----------VEFYKDYDLIVD-SERHKILEDGDR---------CSLIITNLRPEDAGTY 2390

Query: 1918 TCKAINNLGQAVSSIRLNVQSKE 1940
             C   N LG   S   + VQ +E
Sbjct: 2391 KCVITNLLGVETSEAVIRVQERE 2413



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 32/96 (33%), Positives = 46/96 (47%), Gaps = 6/96 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG---- 692
            P+ I PLKS+ ++EGG+  F+  +E    P  K++W   G  I    R+  I        
Sbjct: 2613 PEAIAPLKSIESVEGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGDRP 2670

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
              +L + SL   DSG Y C A +  GV   K+ L V
Sbjct: 2671 VYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+F++ L  +E +E     LEC +   G+     EW    +P+K   R +   + D V 
Sbjct: 317  APKFTKPLETLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVV 374

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L++  V  +D  +Y   A N+ G A +   L V
Sbjct: 375  LEVRHVELDDEALYKVVAKNESGVATSEAELLV 407



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 4/85 (4%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDD 2711
            ++EG  + L+A+V  + +P   ++WFK    +    R     D    L +L I + +  D
Sbjct: 425  VLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLD 482

Query: 2712 SGIYTCKATNLLGEAVSTASIKIED 2736
            SG+Y C+ATN  G+A + A I+IE+
Sbjct: 483  SGVYICQATNDTGKATAEAEIQIEE 507



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 8/129 (6%)

Query: 2216 GLEKIRQLEAQGHSTR-----IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVH 2270
            G+ K     A G +TR     +EV +P+ S P    EL+  T V  G+     C++    
Sbjct: 1350 GMYKCEATNAVGKATRTFDVQVEVPKPRGSKPSLEAELKPVT-VTAGEDTKLVCKISGKP 1408

Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330
             P  +I++  + K L+   R   T+D     L     V ED  EY V A N LG  +++ 
Sbjct: 1409 QP--KIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSA 1466

Query: 2331 SMTVTAKGS 2339
             + V  KG+
Sbjct: 1467 ELLVNEKGA 1475



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 5/112 (4%)

Query: 1166 MYQIEEIS-KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            M ++EE+  +  P F+  L  P  + EG    L CR+   G P   + WF +   V   +
Sbjct: 2212 MVKVEELKGRGVPSFITGLF-PVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDN 2268

Query: 1225 RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIV 1276
            R    Y+    AL++     +D G Y   A N  GS  +SA V  I+R D +
Sbjct: 2269 RVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEV-TIKRKDAI 2319



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 34/144 (23%), Positives = 66/144 (45%), Gaps = 6/144 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P FIT +    ++E +     CRV  K  PK  I W+R+   + + +R    Y+    +L
Sbjct: 2224 PSFITGLFPVQIKEGDKYTLVCRVSGK--PKPTITWFRDNTPVHTDNRVVASYEGSVSAL 2281

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPRGMKRSEALTQM 3946
            ++  +   D+G Y C A N  G   + A ++ K+   +P  ++  +   G++ S+    +
Sbjct: 2282 ELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLESSDMRLDV 2341

Query: 3947 E-ATIKKYTSEVYLTEDDLYDVDK 3969
            +     + T E Y   D + D ++
Sbjct: 2342 KIGGFPRPTVEFYKDYDLIVDSER 2365



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 25/68 (36%), Positives = 36/68 (52%)

Query: 2670 TDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729
            T  + KIEW K+G   T G   + +FD   +TL+  +    D+G Y C  TN  GE+ S+
Sbjct: 2542 TTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSS 2601

Query: 2730 ASIKIEDR 2737
            A I I  +
Sbjct: 2602 ADISITQK 2609



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 3/132 (2%)

Query: 1535 TCRSTTDIVRSTQNEAGLE-QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQ 1593
            T  +TT  ++ T+ +   E Q+ +  D         V       P  T  LK VE++EGQ
Sbjct: 682  TDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEVEEGQ 741

Query: 1594 RAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCR 1653
             A  + R+  V   T  VEW+     L    R+          L I + + +D  TY C 
Sbjct: 742  EARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCV 799

Query: 1654 AINALGEAVTSG 1665
            A N +G+    G
Sbjct: 800  ASNQVGKVTCRG 811



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 2/98 (2%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            V KP F   +K  EVTE      E   T    P   VEW+     ++   RF+   +   
Sbjct: 1182 VVKPDFKTKLKPMEVTEESVAKFEVRSTGFPQP--EVEWFLGSTKIEDSGRFRVVSEQDR 1239

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
              L I     +D GTY C   N  G A + + +KV  K
Sbjct: 1240 HELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK 1277



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 5/99 (5%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            KP  + P++   Q+ E  +   E Q+    +P  ++ WY     L +G+ +K+  D G  
Sbjct: 1735 KPVIVKPLS-NLQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791

Query: 2970 TLDLV--DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            T  L+  D    DSG+Y C A N+ G+A + +T+  T +
Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 36/115 (31%), Positives = 52/115 (45%), Gaps = 4/115 (3%)

Query: 3403 SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKS 3462
            S+ R  D  VE + GKAP F   L  +E + EG       +L+    P    EW  NG  
Sbjct: 1916 SVSRTFDVRVEVD-GKAPRFVSELRPVE-VFEGNEVSLVCKLSAEAKPTF--EWSRNGSP 1971

Query: 3463 LKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
            ++  +R +   D  +  L+      ED G Y C A N +G A + A + V+ K N
Sbjct: 1972 VRLDNRVQASFDGRYSTLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGN 2026



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 21/51 (41%), Positives = 29/51 (56%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            V+WY + KPL+ G R T           ++S  PED+G Y C A NA+G+A
Sbjct: 1313 VKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKA 1363



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 6/102 (5%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            + GN P+      D+   E   A F+         + +VEW H  + ++ G + K   + 
Sbjct: 2023 KKGNRPQPIGMIRDIEGYEGGQARFDVHFT----GNPKVEWLHGEEQIIHGEKYKISENP 2078

Query: 3613 GFVI--LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
            G  +  L +G +   D G YTC A+N  G+AT+   L VK +
Sbjct: 2079 GEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 6/138 (4%)

Query: 1023 LEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFN 1082
            L  ASR      EE+K    P F+  L    +I EG       RV  +   T+T  W+ +
Sbjct: 2204 LGTASRTVMVKVEELKGRGVPSFITGLFPV-QIKEGDKYTLVCRVSGKPKPTIT--WFRD 2260

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
               + + NR+   ++    AL++  ++  D+G+Y   A N+ G    SA +T++ + +I 
Sbjct: 2261 NTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIP 2320

Query: 1143 TSSIHRGLYEKTRHIEES 1160
            T  +  GL E T  +E S
Sbjct: 2321 TFVV--GLKE-TEGLESS 2335



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%)

Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367
            ++ P+F + +  ++ +EG  V  + R+   G  T +VEWF N   I    RF    E D 
Sbjct: 120  LRKPEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDL 177

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
             +L +      D+  Y C AT++ G++     L V  K
Sbjct: 178  YSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEK 215



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 51/200 (25%), Positives = 72/200 (36%), Gaps = 18/200 (9%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595
            G P     W  +   L    R    H      +DI +V  ND+G Y C+A N+AG     
Sbjct: 538  GKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRT 597

Query: 2596 XXXXXXXXXXI-IDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKL 2654
                        I Q +         ++   + K P         +AP  T  L+  ++L
Sbjct: 598  FIVNVEVLFVAGISQVIG-------SIRFIVLAKKP-------AGEAPEITESLQEMEEL 643

Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714
             EG  V L  +      P    EWFK    +  G R K T      TL+I   R DD+  
Sbjct: 644  -EGNPVTLTCKFTGTPAP--VAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTE 700

Query: 2715 YTCKATNLLGEAVSTASIKI 2734
            Y     N +G   S   ++I
Sbjct: 701  YQVVIRNDIGSVKSETRVRI 720



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 1/102 (0%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474
            EK   P  T P    E +   E       +T   +P   V+W+ +GK ++  SR      
Sbjct: 817  EKMFPPEITRP-ERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPR 875

Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
                 L I  T PED+G Y C A N  G + TT  ++++  +
Sbjct: 876  GDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIEASK 917



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 2/114 (1%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLL 3601
            S TV     E +    P F T    + + E       CR+         + WF +  P+ 
Sbjct: 2208 SRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVH 2265

Query: 3602 TGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI 3655
            T +RV    +     LE+  +   DAGLY C ATN  G  + S ++ +K +  I
Sbjct: 2266 TDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 2/85 (2%)

Query: 644  KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI 703
            +SVTA EG +++    I   G P   + W+K+G  I +S+  +   R    SL ++ +  
Sbjct: 2425 QSVTAQEGFELNKTFIIR--GKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTK 2482

Query: 704  QDSGEYTCRAVSATGVAETKAVLHV 728
            +DSG YTC+AVS+ G A     L V
Sbjct: 2483 EDSGNYTCQAVSSLGKASQSFDLKV 2507



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 11/142 (7%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            + G  PEFT     + + E      + R+      +  VEW  +G+ +    R+KT  D 
Sbjct: 22   DKGTIPEFTKKLQPVTVREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHRIKTTFDG 79

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
                L+I    + D G Y C ATN  G+AT++ ++ VK       E      FK   + +
Sbjct: 80   ERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVK-------ETLRKPEFKQKMQPL 132

Query: 3673 QKLEETLHKREEITIEDEKPNP 3694
            Q LE     R ++ I D KP P
Sbjct: 133  QVLEGD-EVRFDVRI-DGKPTP 152



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 3/94 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F   L+    + EG+    +ARV+ +   T TVEW  +G+++   +RI+T  D     
Sbjct: 27   PEFTKKLQPVT-VREGERISLDARVKGKP--TPTVEWMVDGEKVQDDHRIKTTFDGERCT 83

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            L I     +D G Y  VA N  G+A ++  + V+
Sbjct: 84   LKIMPSERDDEGEYKCVATNEVGQATITTEVLVK 117



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 41/158 (25%), Positives = 62/158 (39%), Gaps = 6/158 (3%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            T AP        I + E        R+   G PK  ++W ++  PI+ ++RLTT      
Sbjct: 216  TSAPEVFGDTAPINITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDE 273

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
              L +    PEDSG Y C A +E G A     + V+      +  +    L+ ++ +E  
Sbjct: 274  CVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKE 333

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYE 1865
            +    R +  V    AP     L G   L E Q    E
Sbjct: 334  T---ARLECTVTGEPAPT-TEWLKGDQPLKETQRIKIE 367



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 4/119 (3%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            RP F   L  +E ++EG  A  + RV  +  P   ++WF    K+    RY    +    
Sbjct: 725  RPDFTKKLKPVE-VEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSY 781

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ 2226
             L I  T  +D  TY C A+N++G+      LKV   +    +   P   EKI  LE +
Sbjct: 782  TLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVT-EKMFPPEITRPERTEKIVLLEKE 839



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 21/65 (32%), Positives = 38/65 (58%)

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            +P   ++WFK+G  +   +RL         TL+I++   +D+G YTC+A N +G + +T 
Sbjct: 850  NPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTI 909

Query: 2731 SIKIE 2735
             ++IE
Sbjct: 910  DVQIE 914



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 57/242 (23%), Positives = 85/242 (35%), Gaps = 38/242 (15%)

Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737
            T + R ++ ++ EK   P F  +    I V +G  +    ++     P   + W+ +G+P
Sbjct: 1265 TAYSRADLKVK-EKDCAPEFVGDQAAPIVVRQGEDIDIGAQI--TAKPKPNVKWYKDGKP 1321

Query: 3738 FATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLES 3797
               G R             +      D G Y C ATN  G AT T         D+ +E 
Sbjct: 1322 LRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTF--------DVQVEV 1373

Query: 3798 QLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKE 3857
              P+G       EL           +P+              TV   E  +  C++  K 
Sbjct: 1374 PKPRGSKPSLEAEL-----------KPV--------------TVTAGEDTKLVCKISGKP 1408

Query: 3858 DPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKA 3917
             PK  I+W ++ K L    R    YD     L       ED  EY   A N+ G   T A
Sbjct: 1409 QPK--IDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSA 1466

Query: 3918 TI 3919
             +
Sbjct: 1467 EL 1468



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F + ++  + + EG       +L      T   EW ++G PV   +R+   F+  Y  
Sbjct: 1932 PRFVSELRP-VEVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYST 1988

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            L   +  + D G Y+C A N  G A++ A L +  K
Sbjct: 1989 LKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKK 2024



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 7/100 (7%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLV--PVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            EPP F++++  + ++ EG    FE +L+   V   D K+EW  +G+    G       D 
Sbjct: 2515 EPPSFLSELPPL-QVREG----FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDG 2569

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
              + L       +++G Y+C+ TNK G  S+ A++  T K
Sbjct: 2570 RNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 7/101 (6%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ----TY 1095
            T+KP  + PLK     VEG  A F+  VE  +     V+WY  G +IT   R +    T 
Sbjct: 2610 TRKPEAIAPLKSIES-VEGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTD 2666

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             D     L I S++  DSG Y  +A N  G   + + + V+
Sbjct: 2667 GDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVK 2707



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 4/117 (3%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566
            +P FT+ L  P E+ EGQ A  + RVV  G P+   EW+    +L    R+    +    
Sbjct: 725  RPDFTKKLK-PVEVEEGQEARLDVRVV--GTPTPNVEWFCGTTKLTDTDRYEFIEEGDSY 781

Query: 2567 TLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKE 2623
            TL I + V +D   Y C A N+ G                  +  RPE  E+I L E
Sbjct: 782  TLIIKTTVRDDDDTYKCVASNQVG-KVTCRGDLKVTEKMFPPEITRPERTEKIVLLE 837



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 36/109 (33%), Positives = 50/109 (45%), Gaps = 5/109 (4%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            KPV V+PLSN   V E      E ++   G+P  RV W+H    +  G+ +K   D G  
Sbjct: 1735 KPVIVKPLSNLQ-VEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791

Query: 1236 ALDIIHATSA--DTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
               +I   S   D+G Y   AVN  G A + A + V  R    T  ++E
Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDE 1840



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 3/97 (3%)

Query: 1843 APRFI-TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            APRF  T L       EG   +    I   P P   V W  +G V+ S +          
Sbjct: 2415 APRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPT--VTWMKDGNVISSSNGVSLRQRGES 2472

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
             +L I+ V  EDSG YTC+A+++LG+A  S  L V++
Sbjct: 2473 YSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEA 2509



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 26/91 (28%), Positives = 41/91 (45%)

Query: 776  LQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHL 835
            L +L  LQ      F+     V+    ++EW KDGR  T        F+   ++L   + 
Sbjct: 2520 LSELPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNA 2579

Query: 836  RAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
              +DAG Y     NK GE+ S+A I +  ++
Sbjct: 2580 TLKDAGRYQCIVTNKFGESSSSADISITQKT 2610



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   M+ ++V E     F+ R+   G P  +VEW +N   I+   R   + +    +L
Sbjct: 123  PEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDLYSL 180

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
             +      D+ TY C A +E G++     L V+ K S
Sbjct: 181  IIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTS 217



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 50/204 (24%), Positives = 79/204 (38%), Gaps = 35/204 (17%)

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
            NI EG       R+   G P  +++W +++K I+ + R+T T       + +S  + ED 
Sbjct: 229  NITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDS 286

Query: 2447 GVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFE 2506
            G Y C A +  G               + +E   P+G+                   +F 
Sbjct: 287  GRYKCTAKSEHG--------TASKEFDVNVEKAKPKGVAP-----------------KFT 321

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566
            KP+ T       E+ E + A  E  V   G+P+   EW      LK   R +   D   V
Sbjct: 322  KPLETL------EIMEKETARLECTVT--GEPAPTTEWLKGDQPLKETQRIKIERDKDSV 373

Query: 2567 TLDINSVVANDAGLYMCKAINRAG 2590
             L++  V  +D  LY   A N +G
Sbjct: 374  VLEVRHVELDDEALYKVVAKNESG 397



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 66/273 (24%), Positives = 99/273 (36%), Gaps = 24/273 (8%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F     +   L+E   + LE  V  +  P  ++ W K+   LT   R+         
Sbjct: 511  APEFAEEEATQLTLIEDDDMTLELHVTGKPKP--EVHWTKDNKPLTEDDRIIIDHKGDSC 568

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXX 2760
             + I ++  +DSG Y C+A N  G    T  + +E   ++ G S        IG++    
Sbjct: 569  IVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEVL-FVAGIS------QVIGSIRFIV 621

Query: 2761 XXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGT 2820
                               L  +   EG+ +   C    +  P    EWF  + P+  G 
Sbjct: 622  LAKKPAGEAPE----ITESLQEMEELEGNPVTLTCKFTGTPAPV--AEWFKASTPVRDGR 675

Query: 2821 RYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQG 2880
            RYK T   +  +L I  T  +D+  Y     N  GS  +   +R T      F       
Sbjct: 676  RYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTK----- 730

Query: 2881 KAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEW 2913
            K     VE+ +EARL       V  T  P  EW
Sbjct: 731  KLKPVEVEEGQEARL----DVRVVGTPTPNVEW 759



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 56/250 (22%), Positives = 88/250 (35%), Gaps = 34/250 (13%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     + W  + K +    RI   +     +++I+     DSGTY C A NK G    
Sbjct: 537  TGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTR 596

Query: 3131 ----QAEI-----------SVK-LECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVV 3174
                  E+           S++ +    K  G+ P  T  +Q +E L +G      C   
Sbjct: 597  TFIVNVEVLFVAGISQVIGSIRFIVLAKKPAGEAPEITESLQEMEEL-EGNPVTLTCKFT 655

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--E 3232
                P    EW+    P+R   R K  +      L I  T+  D+ EY     N  G  +
Sbjct: 656  GTPAP--VAEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVK 713

Query: 3233 DFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVT 3292
              TR  I            ++PD   K++ +E  +G + +        P   +      T
Sbjct: 714  SETRVRITAL---------VRPDFTKKLKPVEVEEGQEARLDVRVVGTPTPNVEWFCGTT 764

Query: 3293 KLVEGQSAHF 3302
            KL +     F
Sbjct: 765  KLTDTDRYEF 774



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 7/107 (6%)

Query: 902  VPESTQKPEFK-TPIKDQISIKEGGFAHFEARLEPI--GDSTLRVEWLKDGRPVEASSRI 958
            V E    P F  T +   ++ +EG    FE     I  G     V W+KDG  + +S+ +
Sbjct: 2409 VQEREHAPRFDGTDLGQSVTAQEG----FELNKTFIIRGKPRPTVTWMKDGNVISSSNGV 2464

Query: 959  TTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
            +        +L I  VT  D+G+YTC+A +++G+A+ S +L +   K
Sbjct: 2465 SLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEAPK 2511



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 24/67 (35%), Positives = 39/67 (58%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P+  V W+++G  I +SN ++        +L +  V  EDSG YTC+A++ LG+A  S
Sbjct: 2443 GKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQS 2502

Query: 1798 STLFVQS 1804
              L V++
Sbjct: 2503 FDLKVEA 2509



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750
            K  PP F  E+   + V EG    F    + V     +I+W  +GR F  G       D 
Sbjct: 2513 KEEPPSFLSELPP-LQVREG--FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDG 2569

Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              I L       +DAG Y C  TNK+G ++++A I+ + K
Sbjct: 2570 RNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 7/93 (7%)

Query: 2648 LKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK----STFDFGLVTLS 2703
            LKS + +  GQ  +    VE    P  K++W+  G  +T G R K    +  D  + TL 
Sbjct: 2619 LKSIESVEGGQARF---DVEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLI 2675

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            I SL+  DSG Y C ATN  G     + +K+++
Sbjct: 2676 IESLKYTDSGTYKCIATNEGGVTTIKSDLKVKE 2708



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 62/276 (22%), Positives = 102/276 (36%), Gaps = 25/276 (9%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            + E    PEF      Q+++ E      E  L   G     V W KD +P+    RI   
Sbjct: 505  IEELLVAPEFAEEEATQLTLIEDDDMTLE--LHVTGKPKPEVHWTKDNKPLTEDDRIIID 562

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
                   + I +VT +D+G Y C A N  G  T     T +   +++  +     +  I+
Sbjct: 563  HKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTR----TFIVNVEVLFVAGISQVIGSIR 618

Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081
            ++  A    K   E  +IT+  + +  L+G N +    +  F     P        EW+ 
Sbjct: 619  FIVLA---KKPAGEAPEITESLQEMEELEG-NPVT--LTCKFTGTPAP------VAEWFK 666

Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
                +    R +         L I   R +D+  Y VV RN  G      S+  ETR  I
Sbjct: 667  ASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG------SVKSETRVRI 720

Query: 1142 DTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKP 1177
             T+ +     +K + +E  +  E    +  +    P
Sbjct: 721  -TALVRPDFTKKLKPVEVEEGQEARLDVRVVGTPTP 755



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 2/95 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P FT  +K + V E Q A  + R+  VG P   VEW      +  ++R   + +     L
Sbjct: 726  PDFTKKLKPVEVEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTL 783

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             +K    +D  TY C A N++G+      L V  K
Sbjct: 784  IIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK 818



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P+ E PK +  +Q +  L EG  A    ++     P   VEWF    K+    R +  + 
Sbjct: 1085 PTGEAPKVVDALQPLEAL-EGDEAKLVCKIT--GSPTPTVEWFKEKAKVVDVRRTKMEYT 1141

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              +  L I     E+ G Y+CVA N  G  ST A L
Sbjct: 1142 DDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATL 1177



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 2/78 (2%)

Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG--LVTLSINSLRNDDSGIYTCKAT 2720
            +A+ +     N K+EW      +  G + K + + G  L +L +  L+++D G YTC A+
Sbjct: 2044 QARFDVHFTGNPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVAS 2103

Query: 2721 NLLGEAVSTASIKIEDRH 2738
            N  G+A   A++ ++D+H
Sbjct: 2104 NESGDATLHANLNVKDKH 2121



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 22/68 (32%), Positives = 36/68 (52%)

Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
            R +P   + W+K+G  L    R+  +  +    L++     DD+GIY C+A N LG A  
Sbjct: 2150 RGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASR 2209

Query: 2729 TASIKIED 2736
            T  +K+E+
Sbjct: 2210 TVMVKVEE 2217



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 46/188 (24%), Positives = 78/188 (41%), Gaps = 36/188 (19%)

Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330
            +P   + +Y +G  LQ   R  I+  +    L +   VP+DAG Y  +A N LG      
Sbjct: 2152 NPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLG------ 2205

Query: 2331 SMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390
                TA  ++         + K+ EL      K   +P  +T   PV          I+E
Sbjct: 2206 ----TASRTV---------MVKVEEL------KGRGVPSFITGLFPV---------QIKE 2237

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G      CR+   G P   + WFR+   +   +R+  +++    ++ +  ++  D G+Y 
Sbjct: 2238 GDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYK 2295

Query: 2451 CRASNLLG 2458
            C A+N  G
Sbjct: 2296 CTATNSQG 2303



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 9/109 (8%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV----H 3745
            +K   P     +K +I+  EGG   FD  VE    P  ++DW+H G     G R      
Sbjct: 2608 QKTRKPEAIAPLK-SIESVEGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQS 2664

Query: 3746 TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            T  D     L I+ +   D+G Y C ATN+ G   TT K     K   +
Sbjct: 2665 TDGDRPVYTLIIESLKYTDSGTYKCIATNEGG--VTTIKSDLKVKEPFI 2711



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 6/97 (6%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK----TTYDF 2032
            KP+   P+K+ E  EG     +  ++    P  +V+WY  G  +  G R+K    T  D 
Sbjct: 2612 KPEAIAPLKSIESVEGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYKIIQSTDGDR 2669

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
                L I      D+GTY C ATN  G     S +KV
Sbjct: 2670 PVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 28/129 (21%), Positives = 56/129 (43%), Gaps = 5/129 (3%)

Query: 3678 TLHKREEITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            T  K  ++ +E  KP    P+FT  + + +++ E      +C V   G+P    +W    
Sbjct: 299  TASKEFDVNVEKAKPKGVAPKFTKPL-ETLEIMEKETARLECTV--TGEPAPTTEWLKGD 355

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795
            +P     R+    D   + L++ ++   D   Y   A N+ G AT+ A++  +   +   
Sbjct: 356  QPLKETQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPF 415

Query: 3796 ESQLPQGMS 3804
              + PQ ++
Sbjct: 416  FKKTPQNVT 424



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 6/115 (5%)

Query: 2348 EGLEKI-RELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDP 2406
            E L K+  + ES       E+      ++P F +  QN+  + EG     D R+    +P
Sbjct: 385  EALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNV-TVLEGDEIRLDARVGGKPEP 443

Query: 2407 TLKVEWFRNEKLIEDSSR--ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            T  V+WF+ ++ + +  R  I    +    S+ I + +  D GVY+C+A+N  G+
Sbjct: 444  T--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGK 496



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 37/126 (29%), Positives = 51/126 (40%), Gaps = 4/126 (3%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V +     P F  +L  P ++ EGQ A  + R+   P PN  VEW+     L    RY  
Sbjct: 718  VRITALVRPDFTKKLK-PVEVEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRYEF 774

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
              +     L I T   +D   Y C A N +G+      L V  K      ++ E   EKI
Sbjct: 775  IEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKMFPPEITRPERT-EKI 833

Query: 1956 QYLEDD 1961
              LE +
Sbjct: 834  VLLEKE 839



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P FT  LK  + + EGQ   L+ +V     PN  +EWF     LT   R +   +    T
Sbjct: 726  PDFTKKLKPVE-VEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRYEFIEEGDSYT 782

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            L I +   DD   Y C A+N +G+      +K+ ++
Sbjct: 783  LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK 818



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 23/91 (25%), Positives = 42/91 (46%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P  E+  ++ +   G  A F  ++ G PTP V W + ++ + +  ++ +  + + G   L
Sbjct: 1477 PKIEKPLQDVKVDAGKKATFNTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQL 1536

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            +I+   P D G Y C   N  GE      +Q
Sbjct: 1537 VIEDAKPEDSGVYKCVVFNDIGETQTKAKLQ 1567



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 21/62 (33%), Positives = 33/62 (53%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            VEE K R  P F++    V ++EG+     CRV+G PKP + W  +   +   +R   +Y
Sbjct: 2215 VEELKGRGVPSFITGLFPVQIKEGDKYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASY 2274

Query: 4162 DG 4163
            +G
Sbjct: 2275 EG 2276



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   LK  + L E   + L+ ++     P   +E++K+   +    R K   D    +
Sbjct: 2320 PTFVVGLKETEGL-ESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            L I +LR +D+G Y C  TNLLG   S A I++++R
Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 5/103 (4%)

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
            +APK   +   PP F++++    V E    +   +V   +D K  IEW ++G+    G  
Sbjct: 2508 EAPK---VKEEPPSFLSELPPLQVREGFEFKLIFKVVTTKDSK--IEWRKDGRAFTPGGN 2562

Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
                +D   ++L       +D+G Y C   N FGE  + A IS
Sbjct: 2563 SEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADIS 2605



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 9/155 (5%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            +V  + P F   +  ++V E        +++   D K  +EW ++G             D
Sbjct: 2511 KVKEEPPSFLSELPPLQVREGFEFKLIFKVVTTKDSK--IEWRKDGRAFTPGGNSEFSFD 2568

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824
               + L  K    +D+G Y C   N+ GE+ +S+ + +  K      ++   A+  ++ +
Sbjct: 2569 GRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK------TRKPEAIAPLKSI 2622

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
            E     Q R DVE++    P+ +   +G TK++ G
Sbjct: 2623 ESVEGGQARFDVEMSAFPLPK-VDWYHGGTKITHG 2656



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 4/113 (3%)

Query: 1295 ARRTKQVREDITVMQA--PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP 1352
            A RT  V+ ++   +   P     L  +    G +  L C++   G    +++W  + KP
Sbjct: 1363 ATRTFDVQVEVPKPRGSKPSLEAELKPVTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKP 1420

Query: 1353 IKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            +K   R  P Y+ +   L       ED   Y   A N+LG   TS  L V  K
Sbjct: 1421 LKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 57/297 (19%), Positives = 108/297 (36%), Gaps = 15/297 (5%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            S P  E   K      G + K   K+ G P P + W +   PL    +    Y+ +T   
Sbjct: 1379 SKPSLEAELKPVTVTAGEDTKLVCKISGKPQPKIDWMKDDKPLKPDKRVLPTYDGET--C 1436

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXY-RHVSETV 186
             L   +    DE EY   A+N+ G    S  + +  +G                    T 
Sbjct: 1437 VLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEKGAAPKIEKPLQDVKVDAGKKATF 1496

Query: 187  EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRES-----IT 241
              +  GT     E  +  + +    G      DD K   F+  ++ +    +S     + 
Sbjct: 1497 NTQVSGTPTPEVEWFK-GESIVEDKGR-FMIIDDAKEGVFQL-VIEDAKPEDSGVYKCVV 1553

Query: 242  KRYVGESDVQISTEIDR-SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRP-RVTW 299
               +GE+  +   ++D   + P +  K+ +K     + E  +    V++ G   P +V W
Sbjct: 1554 FNDIGETQTKAKLQVDAVEVAPKTDKKLDEKEEPITVLEHQEVDMSVKVKGKYVPDKVLW 1613

Query: 300  FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
            FK+   +  +   +I +      L + +    D+GHY   +    G  +++  + V+
Sbjct: 1614 FKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLIIVK 1670



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 2/75 (2%)

Query: 2665 QVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG--LVTLSINSLRNDDSGIYTCKATNL 2722
            +V+   +P  ++ W+     L  G   K   D G    TL +N  +  DSG+Y C A N 
Sbjct: 1756 EVQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNE 1815

Query: 2723 LGEAVSTASIKIEDR 2737
             G+A+S A++++  R
Sbjct: 1816 AGKAISQATLEVTGR 1830



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 46/163 (28%), Positives = 62/163 (38%), Gaps = 14/163 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAH-YEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            R PE     K I  +  GQ     E S  P       ++W++ G  I    R + + +  
Sbjct: 2611 RKPEAIAPLKSIESVEGGQARFDVEMSAFPLPK----VDWYHGGTKITHGGRYKIIQSTD 2666

Query: 3105 ----MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFT-THIQNIE 3159
                +  L I   K TDSGTY C ATN+ G   I   L+   K     P F    I    
Sbjct: 2667 GDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV--KEPFIAPEFEGKDITAPM 2724

Query: 3160 GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
              KDGQ       +     P   I WY +G+ +  S R+   S
Sbjct: 2725 VYKDGQDIKVSFKI--KSRPKPIIAWYKDGKALTSSKRVTLTS 2765



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 29/114 (25%), Positives = 54/114 (47%), Gaps = 3/114 (2%)

Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
           E + ++T ++P+F + +Q L ++ EG    F+ ++     PT +VEW+K+   I    R 
Sbjct: 113 EVLVKETLRKPEFKQKMQPL-QVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRF 169

Query: 820 TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLG 873
             I      SL I   R  DA +Y   A ++ G++     + V  +++     G
Sbjct: 170 EIIDEEDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFG 223



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 2/85 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            +++EG  V  + +++ +  P  K+EWFKN   +    R +   +  L +L I+  R  D+
Sbjct: 133  QVLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDA 190

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDR 2737
              Y C AT+  G++     + ++++
Sbjct: 191  DTYKCIATSEAGKSTCIVELSVKEK 215



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EGD + F+  ++    PT K+EWF N   + +  R++   +    SL I  T   D+  Y
Sbjct: 136  EGDEVRFDVRIDGK--PTPKVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDADTY 193

Query: 2847 TCKATNSKGSAT 2858
             C AT+  G +T
Sbjct: 194  KCIATSEAGKST 205



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 5/156 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E T  PE        I+I EG       R+   G     ++W KD +P++ + R+TT 
Sbjct: 212  VKEKTSAPEVFGDTAP-INITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTT 268

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
                   L +      D+G Y C A +  G A+   ++ +   K      +    LE ++
Sbjct: 269  TKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLE 328

Query: 1022 YLE-DASRYS-KRTEEEVKITQKPRFLGPLKGTNKI 1055
             +E + +R     T E    T+  +   PLK T +I
Sbjct: 329  IMEKETARLECTVTGEPAPTTEWLKGDQPLKETQRI 364



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 35/125 (28%), Positives = 54/125 (43%), Gaps = 3/125 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+       I   EG  + L  R++  G     ++W  + KPIK   R     + D   
Sbjct: 218  APEVFGDTAPINITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECV 275

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE-DTS 1428
            L L    PEDSG Y C A ++ G A     + V   K   +  +    LE ++ +E +T+
Sbjct: 276  LVLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKETA 335

Query: 1429 RYKKT 1433
            R + T
Sbjct: 336  RLECT 340



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L  +  +EG     +  V  +  PT  +EWF     L    RY+   +    +L I
Sbjct: 728  FTKKLKPVEVEEGQEARLDVRVVGT--PTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLII 785

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCT 2866
              T  +D   Y C A+N  G  T  G L+ T
Sbjct: 786  KTTVRDDDDTYKCVASNQVGKVTCRGDLKVT 816



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P+    ++  E  EG    L   +T    PT  VEW+     V    R K  Y     
Sbjct: 1088 EAPKVVDALQPLEALEGDEAKLVCKIT--GSPTPTVEWFKEKAKVVDVRRTKMEYTDDVA 1145

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             L I     ED G Y C A N  GEA T++++ ++
Sbjct: 1146 TLTIPTTRPEDKGMYKCVAKNDFGEASTSATLHIN 1180



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 3/97 (3%)

Query: 2105 PGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF 2164
            P  +P F T L  +E + E   A FE R      P   ++WF    KI    R+R   + 
Sbjct: 1181 PVVKPDFKTKLKPME-VTEESVAKFEVRSTGFPQPE--VEWFLGSTKIEDSGRFRVVSEQ 1237

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                L I     +D+GTY C   N+ G A +   LKV
Sbjct: 1238 DRHELIISDVKVKDAGTYKCTLANQAGTAYSRADLKV 1274



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 3/98 (3%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            SKP     L  P  V+ G++  L C++   G P  +++W  + + +    R    YD   
Sbjct: 1379 SKPSLEAELK-PVTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDKRVLPTYDGET 1435

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
              L    A   D  EY V A N LGS  TSA + V E+
Sbjct: 1436 CVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 3/88 (3%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V  + P F   L+ ++ + EG      C+L     PT   EW RN   +   +R+  + D
Sbjct: 1927 VDGKAPRFVSELRPVE-VFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFD 1983

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
              Y ++   + + ED+G Y C A N+ G
Sbjct: 1984 GRYSTLKFLNAKIEDQGTYSCLAKNVFG 2011



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 1843 APRFITQLNG-PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            AP F+    G P  +  G+  +    I   P P+  V WY +G  LQ   R   S+ +  
Sbjct: 2123 APMFVEDDTGEPITVEAGKELNVIMNIRGNPRPD--VNWYKDGSFLQQTGRMGISSRWDS 2180

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
              L +     +D+G Y C+A N LG A  ++ + V+
Sbjct: 2181 YRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVE 2216



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 5/137 (3%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMV--DEVTTQA-PICTTSLKNVEIKEGQRAHFE 1598
            + ++  ++AG+ + +         RT MV  +E+  +  P   T L  V+IKEG +    
Sbjct: 2185 VFKAVPDDAGIYRCEAKNKLGTASRTVMVKVEELKGRGVPSFITGLFPVQIKEGDKYTLV 2244

Query: 1599 RRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINAL 1658
             R+      T  + W+ +N P+ + +R   +      AL++      D+G Y C A N+ 
Sbjct: 2245 CRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQ 2302

Query: 1659 GEAVTSGIAIVHSKKSI 1675
            G   +S    +  K +I
Sbjct: 2303 GSTSSSAEVTIKRKDAI 2319



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 4/108 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P FI  L  + +++EG       +++    PT  + W++D  P+   +R+ + +     +
Sbjct: 2224 PSFITGLFPV-QIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSA 2280

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV-TADLGIPE 876
            L +  ++  DAG Y   A N  G   S+A + +  +  + T  +G+ E
Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKE 2328



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 21/53 (39%), Positives = 27/53 (50%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            P F      VTV EGE      RV G P P V W+++G  + +  R K T+DG
Sbjct: 27   PEFTKKLQPVTVREGERISLDARVKGKPTPTVEWMVDGEKVQDDHRIKTTFDG 79



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 3/108 (2%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T+++ +    KP F  + + ++ V+EG  V F+ +++       KVEWFKN   +    R
Sbjct: 112  TEVLVKETLRKPEFKQKMQPLQ-VLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGR 168

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTT 1540
            F  I +    +L I D    D+  Y C A +  G       L+ +  T
Sbjct: 169  FEIIDEEDLYSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKT 216



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 26/108 (24%), Positives = 50/108 (46%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            R D++V     P  IT+     K+   +       +    +P   V+W+ +GK ++   R
Sbjct: 810  RGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSR 869

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
                       L+I T   ED+G YTC+A N +G + ++I + +++ +
Sbjct: 870  LNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIEASK 917



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            IV ++G++I     +     P +K  W+ + KPL  G R          +  +     ED
Sbjct: 1291 IVVRQGEDIDIGAQITAKPKPNVK--WYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPED 1348

Query: 2843 SGIYTCKATNSKGSAT 2858
            +G+Y C+ATN+ G AT
Sbjct: 1349 TGMYKCEATNAVGKAT 1364



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 87/379 (22%), Positives = 141/379 (37%), Gaps = 67/379 (17%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF--GF 1234
            P   +PL +   V  GK      ++   G PT  VEWF     V    RF    D   G 
Sbjct: 1477 PKIEKPLQDVK-VDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533

Query: 1235 VALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDA 1294
              L I  A   D+G Y     N +G   T A ++V                + +++    
Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQV----------------DAVEVAPKT 1577

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
             ++  +  E ITV++  +   ++     V+G  V              +V WF +  P+K
Sbjct: 1578 DKKLDEKEEPITVLEHQEVDMSVK----VKGKYV------------PDKVLWFKDDTPVK 1621

Query: 1355 TGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV----------IA 1404
            T    +   E     L L     +D+G Y C++T +LG  +++  + V          IA
Sbjct: 1622 TNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIA 1681

Query: 1405 KKDLILESQHPSG---LEKIQYLEDTSRYK------------KTDIIDESVTIKPRFVTR 1449
            K   + E+ H      + K    +D   YK              ++I     +KP  + +
Sbjct: 1682 KDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLIVNEKAVKP-VIVK 1740

Query: 1450 PKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDII-- 1507
            P S   V E     FE ++    +   +V W+     +  G  ++ + D G     +I  
Sbjct: 1741 PLSNLQVEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTLIVN 1798

Query: 1508 DLIAEDSGIYTCRAVNLVG 1526
            D    DSG+Y C AVN  G
Sbjct: 1799 DSQRHDSGVYKCVAVNEAG 1817



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 2/99 (2%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            + KP+F + ++  +V EG  V  +  +     PT +VEW+ N   +    RF+   +   
Sbjct: 120  LRKPEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDL 177

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
             +L I      D  TY C AT+  G++     + V  K+
Sbjct: 178  YSLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKT 216



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 7/139 (5%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM--GFV 3887
            P F    ++ TV E + +R + RV  K +P   ++W++  + +    R+  V D      
Sbjct: 414  PFFKKTPQNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLF 471

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL---PDIILQNQVPRGMKRSEALT 3944
            SL I      DSG YIC+A ND G+   +A I  ++L   P+   +      +   + +T
Sbjct: 472  SLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMT 531

Query: 3945 QMEATIKKYTSEVYLTEDD 3963
                   K   EV+ T+D+
Sbjct: 532  LELHVTGKPKPEVHWTKDN 550



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 3/98 (3%)

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            K  G+ P+    +Q +E L +G  A   C +     P   +EW+     +    R K   
Sbjct: 1084 KPTGEAPKVVDALQPLEAL-EGDEAKLVCKIT--GSPTPTVEWFKEKAKVVDVRRTKMEY 1140

Query: 3203 DFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
                  L I  T+  D G Y C A N +GE  T AT++
Sbjct: 1141 TDDVATLTIPTTRPEDKGMYKCVAKNDFGEASTSATLH 1178



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 7/98 (7%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+ I  I+D+    EG  A F+       +P  KVEW +  +++ HG +Y+   + G  +
Sbjct: 2028 PQPIGMIRDIEGY-EGGQARFDVHFT--GNP--KVEWLHGEEQIIHGEKYKISENPGEYL 2082

Query: 3342 LDILY--CYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
              ++      E+ G Y CVA+N+ G  +  ANL    K
Sbjct: 2083 YSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 91/377 (24%), Positives = 140/377 (37%), Gaps = 74/377 (19%)

Query: 2216 GLEKIRQLEAQGH-STRIEVE-EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPN 2273
            GL K     +QG  S+  EV  + K + P FV  L+ T  +   +++     V+    P 
Sbjct: 2292 GLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGL---ESSDMRLDVKIGGFPR 2348

Query: 2274 LRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMT 2333
              +EFY +   +  + R  I  D    SL I +  PEDAG Y     N LG  TS     
Sbjct: 2349 PTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETS----- 2403

Query: 2334 VTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQT 2393
                          E + +++E E A  F   ++ + VT Q           +  +  +T
Sbjct: 2404 --------------EAVIRVQEREHAPRFDGTDLGQSVTAQ-----------EGFELNKT 2438

Query: 2394 AHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453
                   I  G P   V W ++  +I  S+ ++        S+ I  V  ED G Y C+A
Sbjct: 2439 ------FIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQA 2492

Query: 2454 SNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQV 2513
             + LG+                L+ + P    K++  E+P    SE P            
Sbjct: 2493 VSSLGK----------ASQSFDLKVEAP----KVK--EEPPSFLSELP------------ 2524

Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSV 2573
               P ++ EG       +VV   D   + EW  +G     G     + D   +TL   + 
Sbjct: 2525 ---PLQVREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNA 2579

Query: 2574 VANDAGLYMCKAINRAG 2590
               DAG Y C   N+ G
Sbjct: 2580 TLKDAGRYQCIVTNKFG 2596



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 3/89 (3%)

Query: 778  DLGELQEGRNAHFEAQLTPV--SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHL 835
            DLG+    +   FE   T +    P   V W KDG  I++S+ ++        SL I+ +
Sbjct: 2422 DLGQSVTAQEG-FELNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKV 2480

Query: 836  RAEDAGSYTVRAVNKLGEAISTASIRVAA 864
              ED+G+YT +AV+ LG+A  +  ++V A
Sbjct: 2481 TKEDSGNYTCQAVSSLGKASQSFDLKVEA 2509



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 7/103 (6%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR---- 3470
            +K + P    PL +IE++ EG  A F+  ++    P  KV+WY  G  +  G R++    
Sbjct: 2608 QKTRKPEAIAPLKSIESV-EGGQARFDVEMSAFPLP--KVDWYHGGTKITHGGRYKIIQS 2664

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            T  D     L I      DSG Y C A N  G     + +KV+
Sbjct: 2665 TDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVK 2707



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 5/96 (5%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            ++P F   +  L+ L EGD   F+ R++    P   ++WF N  KI    R+    +   
Sbjct: 121  RKPEFKQKMQPLQVL-EGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDL 177

Query: 2167 VALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
             +L I  T   D+ TY C AT++ G+  +TC ++++
Sbjct: 178  YSLIIDDTRLSDADTYKCIATSEAGK--STCIVELS 211



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 59/265 (22%), Positives = 98/265 (36%), Gaps = 25/265 (9%)

Query: 3667 SGTESIQKLEETLHKREEITIE-DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDP 3725
            SG    Q   +T     E  I+ +E    P F  E    + + E   +  +  V   G P
Sbjct: 483  SGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLELHV--TGKP 540

Query: 3726 TMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               + W  + +P     R+   +      +DI  +   D+G Y C A NK G  T T  +
Sbjct: 541  KPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIV 600

Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESE 3845
                  +++  + + Q +   +   L +    +AP+           IT+     +EE E
Sbjct: 601  NV----EVLFVAGISQVIGSIRFIVLAKKPAGEAPE-----------ITE-SLQEMEELE 644

Query: 3846 G--VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYI 3903
            G  V   C+      P    EW++    +  G RY+        +L I     +D+ EY 
Sbjct: 645  GNPVTLTCKFTGTPAPV--AEWFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQ 702

Query: 3904 CRAVNDFG--EDFTKATISCKKLPD 3926
                ND G  +  T+  I+    PD
Sbjct: 703  VVIRNDIGSVKSETRVRITALVRPD 727



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 3/96 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P FT  L  +E + EG+ A  + R+  T  PN  VEW+     L    R+    +     
Sbjct: 726  PDFTKKLKPVE-VEEGQEARLDVRVVGTPTPN--VEWFCGTTKLTDTDRYEFIEEGDSYT 782

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            L I  T  +D   Y C A N  G+      +KV  K
Sbjct: 783  LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK 818



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L  +E + E   A FE R T    P  +VEW+     ++   RFR   +     
Sbjct: 1185 PDFKTKLKPME-VTEESVAKFEVRSTGFPQP--EVEWFLGSTKIEDSGRFRVVSEQDRHE 1241

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            L IS    +D+G Y C   N  G A + A +KV+ K
Sbjct: 1242 LIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK 1277



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 54/231 (23%), Positives = 92/231 (39%), Gaps = 34/231 (14%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +V W KD  PV+ ++            LT+   ++ DAGHY C +   +G  TT +   I
Sbjct: 1610 KVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDDAGHYRCESTTKLG--TTISTFLI 1667

Query: 1002 VTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKI------ 1055
            + K + + + +    + K ++L++A      T     + Q+ + +   K TNK+      
Sbjct: 1668 IVKVEWLKDDKP---IAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCG 1724

Query: 1056 ---VEGQSAHFEARVEPQSDLTMT------------------VEWYFNGKQITSANRIQT 1094
               +  + A     V+P S+L +                   V WY    ++      + 
Sbjct: 1725 ANLIVNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKM 1784

Query: 1095 YHDFGY--VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDT 1143
              D G     L +   +  DSGVY  VA N AG+A   A++ V  R    T
Sbjct: 1785 LEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPT 1835



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G  P F +    + + E +     C+L    ++    EW  NG P+   +RV+   D  +
Sbjct: 1929 GKAPRFVSELRPVEVFEGNEVSLVCKLSA--EAKPTFEWSRNGSPVRLDNRVQASFDGRY 1986

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
              L+       D G Y+C A N  G A+   KL VK
Sbjct: 1987 STLKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVK 2022



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 3/149 (2%)

Query: 2875 TQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQ 2934
            T+   G    +AV    +A  +   +   P  +   P ++  +    Q+ EG    L  +
Sbjct: 2481 TKEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPL-QVREGFEFKLIFK 2539

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            V    D   KIEW  +G+    G   + + D   +TL   +   +D+G Y C   NK GE
Sbjct: 2540 VVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGE 2597

Query: 2995 AFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023
            + +S+ +  T K    E     K  E +E
Sbjct: 2598 SSSSADISITQKTRKPEAIAPLKSIESVE 2626



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 3/103 (2%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            +E  +PK   P+F   L  T  + E +TA  EC V    +P    E+    + L+   R 
Sbjct: 308  VEKAKPKGVAPKFTKPLE-TLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRI 364

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             I  D   V L+++H   +D   Y V A N  G  TS   + V
Sbjct: 365  KIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLV 407



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 37/120 (30%), Positives = 54/120 (45%), Gaps = 7/120 (5%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD--FG 1233
            KP F +   N   V EG  I L+ R+    +PT  V+WF   + V    RF    D    
Sbjct: 413  KPFFKKTPQNVT-VLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGD 469

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLED 1293
              +L I +A   D+G Y  +A N  G A   A +++ E   +V     E+   Q+ L+ED
Sbjct: 470  LFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEEL--LVAPEFAEEEATQLTLIED 527



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF--RFGYI 694
           P F    ++VT +EG +I  + R+    +PT  ++W K  Q +    RF  +        
Sbjct: 414 PFFKKTPQNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLF 471

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           SL + +    DSG Y C+A + TG A  +A + +
Sbjct: 472 SLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 505



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 22/74 (29%), Positives = 38/74 (51%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            NV    +P   ++WF + KP+   +R          +L+I  T  ED+G YTC+A N  G
Sbjct: 844  NVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG 903

Query: 2856 SATTSGSLRCTGDK 2869
            +++T+  ++    K
Sbjct: 904  TSSTTIDVQIEASK 917



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 3/95 (3%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH---F 4167
            PV V     + VEE    RF  ++ G+PKPRV W      ++ G+ YK+  D   H    
Sbjct: 1736 PVIVKPLSNLQVEEKSLTRFEVQIAGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTFTL 1795

Query: 4168 DIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
             +  ++++D+G  + +             L+V  R
Sbjct: 1796 IVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 48/194 (24%), Positives = 81/194 (41%), Gaps = 20/194 (10%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTV---- 3100
            G  P+   + +DI     GQ A ++     TG+    +EW +  + I    + +      
Sbjct: 2025 GNRPQPIGMIRDIEGYEGGQ-ARFDVHF--TGNPK--VEWLHGEEQIIHGEKYKISENPG 2079

Query: 3101 -YAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159
             Y + +VV ++   K  D G Y+C A+N+ G A +   L   DK     P F   +++  
Sbjct: 2080 EYLYSLVVGDL---KHEDGGRYTCVASNESGDATLHANLNVKDKHIA--PMF---VEDDT 2131

Query: 3160 GLKDGQSAHFECTVVPV--DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNH 3217
            G      A  E  V+     +P   + WY +G  ++ + R+   S +    L +      
Sbjct: 2132 GEPITVEAGKELNVIMNIRGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPD 2191

Query: 3218 DSGEYVCRAYNKYG 3231
            D+G Y C A NK G
Sbjct: 2192 DAGIYRCEAKNKLG 2205



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F   +   ++ EG    L   ++    PT  + W+ +  PV   +R   +Y+    AL
Sbjct: 2224 PSFITGLFPVQIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSAL 2281

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGL 2075
            ++      D G Y C ATN+ G   +++ V +  K  +
Sbjct: 2282 ELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            L+E + L +   +     PD+K  W+ +GK + Q SR  +       TL++      D+G
Sbjct: 835  LLEKEELVINVTILGNPRPDVK--WFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAG 892

Query: 2983 IYTCKAYNKRGEAFTSSTV 3001
             YTC+A NK G + T+  V
Sbjct: 893  SYTCEAQNKMGTSSTTIDV 911



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 8/154 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+F T    + ++E S A FE R          VEWF     +    R + +++     L
Sbjct: 1185 PDFKTKLKPMEVTEESVAKFEVR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHEL 1242

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ---GIILEPQLPSHFKSGTESIQK 3674
             I  V  +DAG Y C   N+ G A     L+VK +      + +   P   + G +    
Sbjct: 1243 IISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIG 1302

Query: 3675 LEETLHKREEIT-IEDEKP--NPPRFTVEIKDNI 3705
             + T   +  +   +D KP  + PR T+  +D++
Sbjct: 1303 AQITAKPKPNVKWYKDGKPLRDGPRTTIRARDDL 1336



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 5/109 (4%)

Query: 3684 EITIEDEKP--NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            ++ +E  KP  + P    E+K  + V  G      C++   G P  +IDW  + +P    
Sbjct: 1368 DVQVEVPKPRGSKPSLEAELKP-VTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPD 1424

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
             RV    D     L        D  EY   A N+ GS +T+A++  + K
Sbjct: 1425 KRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 5/106 (4%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            I  + + +P  ++PL +L +++E     FE Q+    +P  RV WY     +   +    
Sbjct: 1728 IVNEKAVKPVIVKPLSNL-QVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKM 1784

Query: 822  IFNFGY--VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            + + G    +L +   +  D+G Y   AVN+ G+AIS A++ V  R
Sbjct: 1785 LEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 53/222 (23%), Positives = 93/222 (41%), Gaps = 43/222 (19%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFG--FVALDIMS 1641
            ++++E  EG +A F+           KVEW H  + +  G ++  + N G    +L +  
Sbjct: 2034 IRDIEGYEGGQARFDVHFT----GNPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGD 2089

Query: 1642 CLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHS 1701
               ED G YTC A N       SG A +H+  ++  + +H   +                
Sbjct: 2090 LKHEDGGRYTCVASNE------SGDATLHANLNV--KDKHIAPM---------------F 2126

Query: 1702 AQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTT 1761
             +D+  T  P+     K++ V  N            G+P+  V W ++G  ++ + R+  
Sbjct: 2127 VEDD--TGEPITVEAGKELNVIMNIR----------GNPRPDVNWYKDGSFLQQTGRMGI 2174

Query: 1762 MHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
               +    L +    P+D+G Y C A N+LG A  S T+ V+
Sbjct: 2175 SSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTA--SRTVMVK 2214



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P FI  L  V   EG K     R+   G P   I W ++   +   +R  + +     +L
Sbjct: 2224 PSFITGLFPVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSAL 2281

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATI 734
            ++  + + D+G Y C A ++ G   + A + +  +  I
Sbjct: 2282 ELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 32/92 (34%), Positives = 41/92 (44%), Gaps = 6/92 (6%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK---STH-DFSYVS 2832
            I+ L +I   EG    F+  VE S  P  K++W+     +  G RYK   ST  D    +
Sbjct: 2616 IAPLKSIESVEGGQARFD--VEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGDRPVYT 2673

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            L I      DSG Y C ATN  G  T    L+
Sbjct: 2674 LIIESLKYTDSGTYKCIATNEGGVTTIKSDLK 2705



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 6/116 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F  + + +  V EG+ +  + +++        VEW  +G+ V   HR +   D     
Sbjct: 27   PEFTKKLQPV-TVREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCT 83

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559
            L I+    +D G Y C A N VG   ++  +  + T   +R  + +  ++ +QVLE
Sbjct: 84   LKIMPSERDDEGEYKCVATNEVGQATITTEVLVKET---LRKPEFKQKMQPLQVLE 136



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 2/104 (1%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    PEF       I +++G      A++         V+W KDG+P+    R T  
Sbjct: 1274 VKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQIT--AKPKPNVKWYKDGKPLRDGPRTTIR 1331

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
                     + S    D G Y C A NA+G+AT + ++ +   K
Sbjct: 1332 ARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVEVPK 1375



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF--GF 1634
            AP     L++V++  G++A F  ++      T +VEW+     ++   RF   ++   G 
Sbjct: 1476 APKIEKPLQDVKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIIDDAKEGV 1533

Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVT 1663
              L I    PEDSG Y C   N +GE  T
Sbjct: 1534 FQLVIEDAKPEDSGVYKCVVFNDIGETQT 1562



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 5/111 (4%)

Query: 4071 IVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVS--LPDAVTVEEGEWA 4128
            IV DSQ  +H   + K   +  + +   +  +E +   C P FV   + DAV V  G+  
Sbjct: 1796 IVNDSQ--RHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDEVKDAVYVRGGQEV 1853

Query: 4129 RFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTG 4178
                 + G P P VMW  +   +      K+   G MY+  I K    D+G
Sbjct: 1854 SLMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSG 1904



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 3/82 (3%)

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            V W  +G  I + +        +  +L ++ V  EDSG YTCQA + LG+A  S  L+V 
Sbjct: 2449 VTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKVE 2508

Query: 1404 AKKDLILESQHPSGLEKIQYLE 1425
            A K   ++ + PS L ++  L+
Sbjct: 2509 APK---VKEEPPSFLSELPPLQ 2527



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 8/90 (8%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR----TSNDFGFAALDILTVYGED 1913
            EG  A ++  +  +P P  +V+WY  G  +  G RY+    T  D     L I ++   D
Sbjct: 2626 EGGQARFDVEMSAFPLP--KVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTD 2683

Query: 1914 SGEYTCKAINNLGQAVSSIRLNVQSKESII 1943
            SG Y C A N  G  V++I+ +++ KE  I
Sbjct: 2684 SGTYKCIATNEGG--VTTIKSDLKVKEPFI 2711



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 2/77 (2%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984
            EG+ + L+ +V+ K  P   +EW  +G+ ++   R K T D    TL ++     D G Y
Sbjct: 40   EGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIKTTFDGERCTLKIMPSERDDEGEY 97

Query: 2985 TCKAYNKRGEAFTSSTV 3001
             C A N+ G+A  ++ V
Sbjct: 98   KCVATNEVGQATITTEV 114



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 5/116 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+       +   EG ++    R+   G P  +I+W K+ + I+ + R T+  +     L
Sbjct: 219 PEVFGDTAPINITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVL 276

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV---TPRATIERTSQHPETLQYIQQ 749
            +     +DSG Y C A S  G A  +  ++V    P+    + ++  ETL+ +++
Sbjct: 277 VLSDAKPEDSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEK 332



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 35/148 (23%), Positives = 66/148 (44%), Gaps = 9/148 (6%)

Query: 1663 TSGIAIVHSKKSIYLESQH-EGALPRLNQLEDTSKYQRHSAQDEVI----TQAPVFTMPM 1717
            T  I I   K S+ LE +H E     L ++   ++    +++ E++    T+ P F    
Sbjct: 361  TQRIKIERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTP 420

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF--GYVALNMKYV 1775
            +++ V E      +AR+   G P+  V+W +    +    R   + D      +L +   
Sbjct: 421  QNVTVLEGDEIRLDARV--GGKPEPTVDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNA 478

Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
             P DSG Y C+A N+ G+A   + + ++
Sbjct: 479  KPLDSGVYICQATNDTGKATAEAEIQIE 506



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 52/227 (22%), Positives = 83/227 (36%), Gaps = 19/227 (8%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            I++EE  ++P  F  E      + E      E  V     P   + +  + K L    R 
Sbjct: 503  IQIEELLVAP-EFAEEEATQLTLIEDDDMTLELHV--TGKPKPEVHWTKDNKPLTEDDRI 559

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
             I        +DI    P D+G Y  +A N  G  T    + V     ++  +   + + 
Sbjct: 560  IIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNV----EVLFVAGISQVIG 615

Query: 2352 KIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVE 2411
             IR +  A   K+P        + P  T+ LQ ++ + EG      C+    G P    E
Sbjct: 616  SIRFIVLA---KKP------AGEAPEITESLQEMEEL-EGNPVTLTCKF--TGTPAPVAE 663

Query: 2412 WFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            WF+    + D  R   T      ++TI   R +D   Y     N +G
Sbjct: 664  WFKASTPVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIG 710



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 9/126 (7%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            +K N P+    I+D I+  EGG   FD  V   G+P  +++W H       G +     +
Sbjct: 2023 KKGNRPQPIGMIRD-IEGYEGGQARFD--VHFTGNP--KVEWLHGEEQIIHGEKYKISEN 2077

Query: 3750 FG--FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR--DIVLESQLPQGMSG 3805
             G    +L +  +   D G YTC A+N+ G AT  A +    K    + +E    + ++ 
Sbjct: 2078 PGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDKHIAPMFVEDDTGEPITV 2137

Query: 3806 EKIKEL 3811
            E  KEL
Sbjct: 2138 EAGKEL 2143



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 38/216 (17%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F   L   E +E +++ L+ ++   G     VE++ +   I    R +   + D  +L
Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIG--GFPRPTVEFYKDYDLIVDSERHKILEDGDRCSL 2377

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRY 1430
             + ++ PED+G Y C  TN LG   +   +RV                   Q  E   R+
Sbjct: 2378 IITNLRPEDAGTYKCVITNLLGVETSEAVIRV-------------------QEREHAPRF 2418

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
              TD + +SVT +  F    K+   +I G       K  P       V W K+G  ++  
Sbjct: 2419 DGTD-LGQSVTAQEGFELN-KTF--IIRG-------KPRPT------VTWMKDGNVISSS 2461

Query: 1491 HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            +           +L II +  EDSG YTC+AV+ +G
Sbjct: 2462 NGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLG 2497



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 30/136 (22%), Positives = 57/136 (41%), Gaps = 8/136 (5%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP F+  L  +   EG    F+   + V     KIEW K+G++          F    I+
Sbjct: 2516 PPSFLSELPPLQVREG--FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNIT 2573

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L   +  ++D+G Y C   +  G + + A + +T +      ++ PE +  ++ +E    
Sbjct: 2574 LAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK------TRKPEAIAPLKSIESVEG 2627

Query: 756  YQHQESIEEQTSQRPQ 771
             Q +  +E      P+
Sbjct: 2628 GQARFDVEMSAFPLPK 2643



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 6/98 (6%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY----DMG 3885
            P+ I  +KS  +E  EG +    VE    P  +++WY  G  +  G RY+ +     D  
Sbjct: 2613 PEAIAPLKS--IESVEGGQARFDVEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGDRP 2670

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
              +L I  +   DSG Y C A N+ G    K+ +  K+
Sbjct: 2671 VYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVKE 2708



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 9/128 (7%)

Query: 2233 EVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292
            E    K + P F  +L+  T V EG+    + +V+    P   +E+  +G+ +Q   R  
Sbjct: 18   EASPDKGTIPEFTKKLQPVT-VREGERISLDARVKGKPTPT--VEWMVDGEKVQDDHRIK 74

Query: 2293 ITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEK 2352
             TFD    +L I     +D GEY   A N +G  T  I+  V  K ++    ++PE  +K
Sbjct: 75   TTFDGERCTLKIMPSERDDEGEYKCVATNEVGQAT--ITTEVLVKETL----RKPEFKQK 128

Query: 2353 IRELESAE 2360
            ++ L+  E
Sbjct: 129  MQPLQVLE 136



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F  ++  P ++ EG    ++ RI+  P P  +VEW+ N   + +  R+   ++    +
Sbjct: 123  PEFKQKMQ-PLQVLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYS 179

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            L I      D+  Y C A +  G++   + L+V+ K S
Sbjct: 180  LIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTS 217



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 3/97 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F T+++ + ++ E   A FE R      P+  VEWF    K+    R+R   +     
Sbjct: 1185 PDFKTKLKPM-EVTEESVAKFEVRSTGFPQPE--VEWFLGSTKIEDSGRFRVVSEQDRHE 1241

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            L I     +++G Y+C   N+ G   ++A+LK   K+
Sbjct: 1242 LIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEKD 1278



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 24/107 (22%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            KP  +  +K  +++  G       ++   G    +++W+KD +P++   R+   ++    
Sbjct: 1380 KPSLEAELKP-VTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDKRVLPTYDGETC 1436

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014
             LT     + D   Y   A N +G  +TSA L +V +K    + + P
Sbjct: 1437 VLTFHKAVLEDEAEYKVVAKNELGSVSTSAEL-LVNEKGAAPKIEKP 1482



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 5/86 (5%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG-- 2564
            KP+  + L+   ++ E     +E ++   G+P  R  WY    +L  G+ ++   D G  
Sbjct: 1735 KPVIVKPLSN-LQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAG 2590
              TL +N    +D+G+Y C A+N AG
Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAG 1817



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 3/111 (2%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+F+++++ V ++ EG       +L     P    EW  NG  +   +R +   D     
Sbjct: 1932 PRFVSELRPV-EVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYST 1988

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392
            L  L    E+ G Y C+A N  G  S++A L    K N      + R +EG
Sbjct: 1989 LKFLNAKIEDQGTYSCLAKNVFGSASSQAKLLVKKKGNRPQPIGMIRDIEG 2039



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F+  L++   L E  +   + ++     PT  VE+YKD   I  S R   + +    S
Sbjct: 2320 PTFVVGLKETEGL-ESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
            L I +LR EDAG+Y     N LG   S A IRV  R
Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 6/140 (4%)

Query: 3377 KENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSV-EEEKGKAPVFTVPLSNIENLREG 3435
            K++++L+ +     +  L K+    +S V   +  +   E  + P F     N+  L EG
Sbjct: 370  KDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVL-EG 428

Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF--GFVILEISPTYPEDSGEY 3493
            +    +AR+    +P   V+W+   + +    RF    D       L I    P DSG Y
Sbjct: 429  DEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVY 486

Query: 3494 LCRAYNNYGEAVTTASMKVQ 3513
            +C+A N+ G+A   A ++++
Sbjct: 487  ICQATNDTGKATAEAEIQIE 506



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 24/79 (30%), Positives = 38/79 (48%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V+W+ +GKPL  G R            ++      D G+Y C+ATN  G+AT +  +QV+
Sbjct: 1313 VKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372

Query: 3651 GRQGIILEPQLPSHFKSGT 3669
              +    +P L +  K  T
Sbjct: 1373 VPKPRGSKPSLEAELKPVT 1391



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 54/224 (24%), Positives = 89/224 (39%), Gaps = 41/224 (18%)

Query: 1051 GTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG-YV-ALDIASV 1108
            G  + +EG     +AR +        VEW    +QI    + +   + G Y+ +L +  +
Sbjct: 2032 GMIRDIEGYEGG-QARFDVHFTGNPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDL 2090

Query: 1109 RAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQ 1168
            + ED G YT VA N +G+A                 ++H  L  K +HI           
Sbjct: 2091 KHEDGGRYTCVASNESGDA-----------------TLHANLNVKDKHIA---------- 2123

Query: 1169 IEEISKSKPVFVQPLSNPP-PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
                    P+FV+  +  P  V  GK +++   +   G+P   V W+ +G  +    R  
Sbjct: 2124 --------PMFVEDDTGEPITVEAGKELNVIMNIR--GNPRPDVNWYKDGSFLQQTGRMG 2173

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
                +    L +  A   D G Y   A N LG+A  + +V+V E
Sbjct: 2174 ISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVEE 2217



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 3/68 (4%)

Query: 2806 KIEWFFNNKPLPSGTRYK-STHDFSYV-SLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            K+EW    + +  G +YK S +   Y+ SL +     ED G YTC A+N  G AT   +L
Sbjct: 2056 KVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANL 2115

Query: 2864 RCTGDKNI 2871
                DK+I
Sbjct: 2116 N-VKDKHI 2122



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F+V LK    +E   +  + +I   G P   +E+ K+   I  S R   +      SL
Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIG--GFPRPTVEFYKDYDLIVDSERHKILEDGDRCSL 2377

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
             + +L  +D+G Y C   +  GV  ++AV+ V  R
Sbjct: 2378 IITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 6/99 (6%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL--TYDG 4163
            K R P     L    +VE G+ ARF   ++  P P+V W   G  I +G RYK+  + DG
Sbjct: 2609 KTRKPEAIAPLKSIESVEGGQ-ARFDVEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDG 2667

Query: 4164 ---MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199
               +Y   I   +  D+G  + I             LKV
Sbjct: 2668 DRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 3590 RVEWFHNGKPLLTGSRVKTIN----DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSC 3645
            +V+W+H G  +  G R K I     D     L I  +   D+G Y C ATN  G  T+  
Sbjct: 2643 KVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKS 2702

Query: 3646 KLQVK 3650
             L+VK
Sbjct: 2703 DLKVK 2707



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+F  ++Q + +++EG    F+ R+     P  KVEWF N  K+ +  R+    +  +  
Sbjct: 123  PEFKQKMQPL-QVLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYS 179

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
            L I      ++  Y+C+AT++ G+ +    L    K
Sbjct: 180  LIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEK 215



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 5/112 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F  PL+++  ME      E  +   G+P    EWLK  Q ++ + R         + L
Sbjct: 318 PKFTKPLETLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVVL 375

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV---TPRATIERTSQHPETLQ 745
           ++  + + D   Y   A + +GVA ++A L V   T +   ++T Q+   L+
Sbjct: 376 EVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLE 427



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 7/131 (5%)

Query: 1432 KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH 1491
            + +++    T KP F   P+++  V+EG  +  + ++    +    V+WFK  Q V    
Sbjct: 402  EAELLVNEATEKPFFKKTPQNV-TVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEG 458

Query: 1492 RFRPIHD--FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE 1549
            RF  + D      +L I +    DSG+Y C+A N  G       +            + E
Sbjct: 459  RFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEE 518

Query: 1550 AGLEQIQVLED 1560
            A   Q+ ++ED
Sbjct: 519  A--TQLTLIED 527



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 7/103 (6%)

Query: 902  VPESTQKPEFK-TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--I 958
            V E+T+KP FK TP    +++ EG     +AR+    + T  V+W K  + V    R  I
Sbjct: 407  VNEATEKPFFKKTP--QNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLI 462

Query: 959  TTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                     +L I +    D+G Y C+A N  G+AT  A + I
Sbjct: 463  VDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 505



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 31/137 (22%), Positives = 57/137 (41%), Gaps = 3/137 (2%)

Query: 729 TPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNA 788
           T   TI+ T     T   +    D    + +  +      RP F + L+ + E++EG+ A
Sbjct: 685 TTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPV-EVEEGQEA 743

Query: 789 HFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAV 848
             + ++  V  PT  VEW+     +T + R   I      +L I     +D  +Y   A 
Sbjct: 744 RLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVAS 801

Query: 849 NKLGEAISTASIRVAAR 865
           N++G+      ++V  +
Sbjct: 802 NQVGKVTCRGDLKVTEK 818



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 16/126 (12%)

Query: 3830 PKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P+F+  Q     V + E +    ++  K  PK  ++WY++GK L  G R          +
Sbjct: 1281 PEFVGDQAAPIVVRQGEDIDIGAQITAK--PKPNVKWYKDGKPLRDGPRTTIRARDDLYN 1338

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEA 3948
              +L    ED+G Y C A N  G    KAT    +  D+ ++   PRG K S     +EA
Sbjct: 1339 CKVLSAKPEDTGMYKCEATNAVG----KAT----RTFDVQVEVPKPRGSKPS-----LEA 1385

Query: 3949 TIKKYT 3954
             +K  T
Sbjct: 1386 ELKPVT 1391



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 35/148 (23%), Positives = 57/148 (38%), Gaps = 5/148 (3%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            + L  +    G++    C +  S  P  KI+W  ++KPL    R   T+D     L    
Sbjct: 1385 AELKPVTVTAGEDTKLVCKI--SGKPQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHK 1442

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAK 2897
               ED   Y   A N  GS +TS  L    +K      + P     ++A ++A       
Sbjct: 1443 AVLEDEAEYKVVAKNELGSVSTSAEL-LVNEKGAAPKIEKPLQDVKVDAGKKATFNTQVS 1501

Query: 2898 GRRPSVPDTEYPKPEWIIPIAAEHQLVE 2925
            G     P+ E+ K E I+       +++
Sbjct: 1502 G--TPTPEVEWFKGESIVEDKGRFMIID 1527



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            V++K     + +  S   + E   T+FE Q+A  G+P  +V W+     L+    +  + 
Sbjct: 1729 VNEKAVKPVIVKPLSNLQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKMLE 1786

Query: 4027 DFGYVAMNF--GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            D G              DSG Y C A N  G   ++A ++ TG+P
Sbjct: 1787 DSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRP 1831



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            +E  +  NV +  R  P  D    V W+ +G  ++   R   +  +D   L +    P+D
Sbjct: 2137 VEAGKELNVIMNIRGNPRPD----VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDD 2192

Query: 1380 SGVYTCQATNQLGEAVTSCALRV 1402
            +G+Y C+A N+LG A  +  ++V
Sbjct: 2193 AGIYRCEAKNKLGTASRTVMVKV 2215



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 19/58 (32%), Positives = 30/58 (51%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            + +P   + WY +G  L+Q  R  ++S +    L +      D+GIY C+A NK G A
Sbjct: 2150 RGNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTA 2207



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 2/102 (1%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            Q+ EG    L  +V  K  P   I W+ +   +   +R   + +     L+L ++   D+
Sbjct: 2234 QIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLSDA 2291

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023
            G+Y C A N +G   +S+ V    KD +       K TEGLE
Sbjct: 2292 GLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLE 2333



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 29/129 (22%), Positives = 55/129 (42%), Gaps = 8/129 (6%)

Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242
            LS  PP+   +    +   + +     ++EW  +GR+ T G   +  +D   + L   +A
Sbjct: 2520 LSELPPLQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNA 2579

Query: 1243 TSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVR 1302
            T  D G Y     N  G + +SA + + ++      T+  +AI  ++ +E       Q R
Sbjct: 2580 TLKDAGRYQCIVTNKFGESSSSADISITQK------TRKPEAIAPLKSIESV--EGGQAR 2631

Query: 1303 EDITVMQAP 1311
             D+ +   P
Sbjct: 2632 FDVEMSAFP 2640



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           +P   E+        +  +   E  + G P P V WT+   PL E ++  +   +  GD 
Sbjct: 511 APEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIII---DHKGDS 567

Query: 130 SLL-IKQIGPGDEGEYTCTARNQYG 153
            ++ I  + P D G Y C A+N+ G
Sbjct: 568 CIVDIMAVTPNDSGTYKCEAKNKAG 592



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 6/119 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P FT ++K  ++V EG     D RV  VG PT  ++WF          R   + +     
Sbjct: 726  PDFTKKLKP-VEVEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSYT 782

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELER 3813
            L I      D   Y C A+N+ G  T    +  + K   +   ++ +    EKI  LE+
Sbjct: 783  LIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEK---MFPPEITRPERTEKIVLLEK 838



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            KP     +K   VT G    L   ++    P  +++W  + +P++   R   TYD     
Sbjct: 1380 KPSLEAELKPVTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDKRVLPTYDGETCV 1437

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
            L    A  ED   Y   A N +G   T++ + V+ K
Sbjct: 1438 LTFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 54/253 (21%), Positives = 95/253 (37%), Gaps = 34/253 (13%)

Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748
            +EK   P+    ++D + V  G    F+ +V   G PT  ++WF          R   ++
Sbjct: 1471 NEKGAAPKIEKPLQD-VKVDAGKKATFNTQVS--GTPTPEVEWFKGESIVEDKGRFMIID 1527

Query: 3749 DF--GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
            D   G   L I+     D+G Y C   N  G   T AK+   A  ++  ++        E
Sbjct: 1528 DAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTKAKLQVDAV-EVAPKTDKKLDEKEE 1586

Query: 3807 KIKELERGRISDAPK------EEPIV----STPPKFITQIKSH--------TVEES---E 3845
             I  LE   +  + K       + ++     TP K  T  K H        T+ ++   +
Sbjct: 1587 PITVLEHQEVDMSVKVKGKYVPDKVLWFKDDTPVKTNTTRKIHSEGRMYYLTLTDASLDD 1646

Query: 3846 GVRFECRVEPKEDPKL-------RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAED 3898
               + C    K    +       ++EW ++ K +      +  +  G  +L + +V  +D
Sbjct: 1647 AGHYRCESTTKLGTTISTFLIIVKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQD 1706

Query: 3899 SGEYICRAVNDFG 3911
             G Y C+  N  G
Sbjct: 1707 KGVYKCKVTNKLG 1719



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 34/105 (32%), Positives = 45/105 (42%), Gaps = 7/105 (6%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            DI     T KP  +   KSIE+V EG    F+ ++        KV+W+  G  +T G R+
Sbjct: 2603 DISITQKTRKPEAIAPLKSIESV-EGGQARFDVEMSAFPLP--KVDWYHGGTKITHGGRY 2659

Query: 1494 RPIH----DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            + I     D     L I  L   DSG Y C A N  G   +   L
Sbjct: 2660 KIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDL 2704



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 8/90 (8%)

Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSRF----TET 1629
            T+ P     LK++E  EG +A F+   + +S   L KV+WYH    +  G R+    +  
Sbjct: 2610 TRKPEAIAPLKSIESVEGGQARFD---VEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTD 2666

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
             +     L I S    DSGTY C A N  G
Sbjct: 2667 GDRPVYTLIIESLKYTDSGTYKCIATNEGG 2696



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P  T  L+ V ++EG+R   + R+      T  VEW  + + ++   R   T +     L
Sbjct: 27   PEFTKKLQPVTVREGERISLDARV--KGKPTPTVEWMVDGEKVQDDHRIKTTFDGERCTL 84

Query: 1638 DIMSCLPEDSGTYTCRAINALGEA-VTSGIAI 1668
             IM    +D G Y C A N +G+A +T+ + +
Sbjct: 85   KIMPSERDDEGEYKCVATNEVGQATITTEVLV 116



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 21/64 (32%), Positives = 30/64 (46%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   V WYKDG  +  + R+     +    L +     +DAG Y   A NKLG A  T 
Sbjct: 2152 NPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTV 2211

Query: 859  SIRV 862
             ++V
Sbjct: 2212 MVKV 2215



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 36/118 (30%), Positives = 50/118 (42%), Gaps = 10/118 (8%)

Query: 1694 TSKYQRHSAQDEV-ITQA---PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRN 1749
            T+K+   S+  ++ ITQ    P    P+K I   E   A F+  +     PK  V+W   
Sbjct: 2592 TNKFGESSSSADISITQKTRKPEAIAPLKSIESVEGGQARFDVEMSAFPLPK--VDWYHG 2649

Query: 1750 GVPIEASNRL----TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            G  I    R     +T  D     L ++ +   DSGTY C A NE G     S L V+
Sbjct: 2650 GTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVK 2707



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 7/88 (7%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL----TSD 2965
            KPE I P+ +   +  GQ       VE    P  K++WY  G  +  G R+K+      D
Sbjct: 2612 KPEAIAPLKSIESVEGGQARF---DVEMSAFPLPKVDWYHGGTKITHGGRYKIIQSTDGD 2668

Query: 2966 FGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
                TL +  +   DSG Y C A N+ G
Sbjct: 2669 RPVYTLIIESLKYTDSGTYKCIATNEGG 2696



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 1172 ISKSKPVFVQPLSNPP----PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            + K+KP  V P    P     + E +   LEC +   G+P    EW    + +    R K
Sbjct: 308  VEKAKPKGVAPKFTKPLETLEIMEKETARLECTVT--GEPAPTTEWLKGDQPLKETQRIK 365

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
               D   V L++ H    D   Y V A N  G A + A + V E ++
Sbjct: 366  IERDKDSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATE 412



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 7/125 (5%)

Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDL 1073
            G+ K     D    S      +    KP F   LK   ++ E   A FE R    PQ + 
Sbjct: 1158 GMYKCVAKNDFGEASTSATLHINPVVKPDFKTKLKPM-EVTEESVAKFEVRSTGFPQPE- 1215

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
               VEW+    +I  + R +   +     L I+ V+ +D+G Y     N AG A   A +
Sbjct: 1216 ---VEWFLGSTKIEDSGRFRVVSEQDRHELIISDVKVKDAGTYKCTLANQAGTAYSRADL 1272

Query: 1134 TVETR 1138
             V+ +
Sbjct: 1273 KVKEK 1277



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F T LK  +   E    +   +V     P  ++EWF     +    R +   +     
Sbjct: 1185 PDFKTKLKPMEVTEESVAKF---EVRSTGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRHE 1241

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            L I+ ++  D+G Y C   N  G A S A +K++++
Sbjct: 1242 LIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK 1277



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG-YI- 694
            PQ I  ++ +   EGG+  F+      G+P  K+EWL   + I    ++      G Y+ 
Sbjct: 2028 PQPIGMIRDIEGYEGGQARFDVHF--TGNP--KVEWLHGEEQIIHGEKYKISENPGEYLY 2083

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            SL +  L  +D G YTC A + +G A   A L+V
Sbjct: 2084 SLVVGDLKHEDGGRYTCVASNESGDATLHANLNV 2117



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 4/69 (5%)

Query: 94   KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQY 152
            ++ G P P ++W R   P+   N+    Y    G VS L +K++   D G Y CTA N  
Sbjct: 2246 RVSGKPKPTITWFRDNTPVHTDNRVVASYE---GSVSALELKEMKLSDAGLYKCTATNSQ 2302

Query: 153  GEAICSVYI 161
            G    S  +
Sbjct: 2303 GSTSSSAEV 2311



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F +    L + E        +++   DS  ++EW  +G+    G   +   D   + 
Sbjct: 2516 PPSFLSELPPLQVREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNIT 2573

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L       +DAG Y C  TN+ GE++ S  + +
Sbjct: 2574 LAFKNATLKDAGRYQCIVTNKFGESSSSADISI 2606



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 8/116 (6%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+S L  +  +EG        V  ++D   KIEW  + +    G   + + D   ++L  
Sbjct: 2519 FLSELPPLQVREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNITLAF 2576

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAE 2891
             +   +D+G Y C  TN  G +++S       D +I   T+ P+  A L+++E  E
Sbjct: 2577 KNATLKDAGRYQCIVTNKFGESSSS------ADISITQKTRKPEAIAPLKSIESVE 2626



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 3/98 (3%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            KP F Q +  P  V EG  +  + R++  G PT +VEWF N   +    RF+   +    
Sbjct: 122  KPEFKQKMQ-PLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRFEIIDEEDLY 178

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273
            +L I     +D   Y   A +  G +     + V E++
Sbjct: 179  SLIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKT 216



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 5/117 (4%)

Query: 3950 IKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEW 4009
            + K  S V  +E +L   +  + P F    Q+ T L E +  + + ++   G P   V+W
Sbjct: 391  VAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVL-EGDEIRLDARVG--GKPEPTVDW 447

Query: 4010 FFNGKPLLHKNRFTPIYDF--GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064
            F   + +  + RF  + D      ++  G   P DSG Y+C+ATN  G    +A I+
Sbjct: 448  FKGDQKVAEEGRFLIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQ 504



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 5/108 (4%)

Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485
            D    K    +  +  ++P F  + K +E V EGQ    + ++      N  VEWF    
Sbjct: 708  DIGSVKSETRVRITALVRPDFTKKLKPVE-VEEGQEARLDVRVVGTPTPN--VEWFCGTT 764

Query: 1486 PVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR 1533
             +T   R+  I +     L I   + +D   Y C A N VG  +V+CR
Sbjct: 765  KLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVG--KVTCR 810



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 34/117 (29%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P F + L  P  V EG+   L+ R+  +G PT  VEWF     +T   R++   +    
Sbjct: 725  RPDFTKKLK-PVEVEEGQEARLDVRV--VGTPTPNVEWFCGTTKLTDTDRYEFIEEGDSY 781

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLE 1292
             L I      D   Y   A N +G       ++V E+      T+ E+  E+I LLE
Sbjct: 782  TLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKMFPPEITRPERT-EKIVLLE 837



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 6/78 (7%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799
            PK  V+W ++G P+    R T           +    PED+G Y C A N +G+A  +  
Sbjct: 1309 PKPNVKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFD 1368

Query: 1800 LFVQ------SKASLQLE 1811
            + V+      SK SL+ E
Sbjct: 1369 VQVEVPKPRGSKPSLEAE 1386



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 7/101 (6%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            ++ G RP  +  +  +E   EG +A F+  V    +P   ++W H  ++I  G +Y+ + 
Sbjct: 2022 KKKGNRPQPIGMIRDIEGY-EGGQARFD--VHFTGNPK--VEWLHGEEQIIHGEKYKISE 2076

Query: 2163 DFGYVALDILY--TYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            + G     ++      ED G Y C A+N+ G+A     L V
Sbjct: 2077 NPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNV 2117



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 18/64 (28%), Positives = 32/64 (50%)

Query: 2138 DPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            +P   ++W+ +G  ++   R   +  +    L +     +D+G Y C+A NKLG A  T 
Sbjct: 2152 NPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTV 2211

Query: 2198 TLKV 2201
             +KV
Sbjct: 2212 MVKV 2215



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            V WY +   L+   R   ++ +    L +   +P+D+G Y C A N LG A  + +  V 
Sbjct: 2157 VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVE 2216

Query: 1671 SKKSIYLESQHEGALPRLNQLEDTSKY 1697
              K   + S   G  P   Q+++  KY
Sbjct: 2217 ELKGRGVPSFITGLFP--VQIKEGDKY 2241



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F + +K+    E+     + ++   G P+  VE+ ++   I  S R   + D    +L
Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKI--GGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSL 2377

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             +  + PED+GTY C   N LG   + + + VQ +
Sbjct: 2378 IITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 5/95 (5%)

Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-- 1626
            +V+E T + P    + +NV + EG     + R+    + T  V+W+  ++ +    RF  
Sbjct: 406  LVNEAT-EKPFFKKTPQNVTVLEGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLI 462

Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
             +       +L I +  P DSG Y C+A N  G+A
Sbjct: 463  VDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKA 497



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 1036 EVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRI 1092
            ++K+T+K   P    P + T KIV  +       V    +    V+W+ +GK I  ++R+
Sbjct: 812  DLKVTEKMFPPEITRPER-TEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRL 870

Query: 1093 QTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                      L+I +   ED+G YT  A+N  G +  +  + +E
Sbjct: 871  NIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQIE 914



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            ++KG  P     + +IE   EG  A F+   T     N KVEW    + +  G +++   
Sbjct: 2022 KKKGNRPQPIGMIRDIEGY-EGGQARFDVHFTG----NPKVEWLHGEEQIIHGEKYKISE 2076

Query: 3474 DFGFVI--LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            + G  +  L +     ED G Y C A N  G+A   A++ V+ K
Sbjct: 2077 NPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 6/128 (4%)

Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028
            K++PP F++++     L   E  +F+     V   + K+EW  +G+           +D 
Sbjct: 2513 KEEPPSFLSELPP---LQVREGFEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDG 2569

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIR 4088
              + + F     +D+G Y C  TN +G   + A I  T K       +    +KSIE + 
Sbjct: 2570 RNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK---TRKPEAIAPLKSIESVE 2626

Query: 4089 EMEASWQV 4096
              +A + V
Sbjct: 2627 GGQARFDV 2634



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 7/104 (6%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRI--- 958
            + + T+KPE   P+K   S+ EGG A F+  +        +V+W   G  +    R    
Sbjct: 2606 ITQKTRKPEAIAPLKSIESV-EGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYKII 2662

Query: 959  -TTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +T  +     L I+S+   D+G Y C A N  G  T  ++L +
Sbjct: 2663 QSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 25/110 (22%), Positives = 45/110 (40%), Gaps = 2/110 (1%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P  ++EG       R+   P P   ++W  + K ++   R  T+       L +     E
Sbjct: 227  PINITEGDELDLSVRVRGKPKPE--IKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPE 284

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
            DSG Y C A +  G A     +NV+  +      +    LE ++ +E ++
Sbjct: 285  DSGRYKCTAKSEHGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIMEKET 334



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP FT  L++ + ++E +   LE  V     P    EW K    L    R+K   D   V
Sbjct: 317  APKFTKPLETLE-IMEKETARLECTVTGEPAPTT--EWLKGDQPLKETQRIKIERDKDSV 373

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             L +  +  DD  +Y   A N  G A S A + + +
Sbjct: 374  VLEVRHVELDDEALYKVVAKNESGVATSEAELLVNE 409



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 53/233 (22%), Positives = 86/233 (36%), Gaps = 23/233 (9%)

Query: 3558 PEFTTTPS-DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PEF    +  L L E+     E  +         V W  + KPL    R+   +     I
Sbjct: 512  PEFAEEEATQLTLIEDDDMTLELHV--TGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCI 569

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            ++I  V   D+G Y C+A N+ G  T +  + V+     +L       F +G   I ++ 
Sbjct: 570  VDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVE-----VL-------FVAG---ISQVI 614

Query: 3677 ETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR 3736
             ++  R  +  +      P  T  +++ ++  EG PV   C+    G P    +WF    
Sbjct: 615  GSI--RFIVLAKKPAGEAPEITESLQE-MEELEGNPVTLTCKF--TGTPAPVAEWFKAST 669

Query: 3737 PFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
            P   G R           L I      D  EY     N  GS  +  ++  +A
Sbjct: 670  PVRDGRRYKITTTDNTTTLTIKETRLDDNTEYQVVIRNDIGSVKSETRVRITA 722



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+   K     +   AKFE +  G P P V W      + +  ++ +  +EQ     L
Sbjct: 1185 PDFKTKLKPMEVTEESVAKFEVRSTGFPQPEVEWFLGSTKIEDSGRFRV-VSEQDRH-EL 1242

Query: 132  LIKQIGPGDEGEYTCTARNQYGEA 155
            +I  +   D G Y CT  NQ G A
Sbjct: 1243 IISDVKVKDAGTYKCTLANQAGTA 1266



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 32/129 (24%), Positives = 50/129 (38%), Gaps = 7/129 (5%)

Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAV----NQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870
            ++ + K +      +  R  DV+V V       P    +L  P  ++ G+     C+I  
Sbjct: 1348 DTGMYKCEATNAVGKATRTFDVQVEVPKPRGSKPSLEAELK-PVTVTAGEDTKLVCKISG 1406

Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
             P P  +++W  + K L+   R   + D     L       ED  EY   A N LG   +
Sbjct: 1407 KPQP--KIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVST 1464

Query: 1931 SIRLNVQSK 1939
            S  L V  K
Sbjct: 1465 SAELLVNEK 1473



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F+T    ++ + EG      C++         + WF++  PV   +R    ++    A
Sbjct: 2224 PSFITGLFPVQ-IKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSA 2280

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            L++ ++   D+G+Y C A N  G+   S  +T +
Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIK 2314



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F+  +K     ES  +R + ++     P+  +E+Y++  L+    R++ + D    SL
Sbjct: 2320 PTFVVGLKETEGLESSDMRLDVKIGGF--PRPTVEFYKDYDLIVDSERHKILEDGDRCSL 2377

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             I  +  ED+G Y C   N  G + ++A I
Sbjct: 2378 IITNLRPEDAGTYKCVITNLLGVETSEAVI 2407



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 3/116 (2%)

Query: 748 QQLEDYSKYQHQESIE-EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
           Q   D  K   +  I+ E+    P+F         L E  +   E  +T    P   V W
Sbjct: 489 QATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLELHVT--GKPKPEVHW 546

Query: 807 YKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            KD +P+T   RI          ++IM +   D+G+Y   A NK G    T  + V
Sbjct: 547 TKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNV 602



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 24/97 (24%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTI 1489
            Y + D+  +     P FV    +   V +G+ +    ++      N+K  W+K+G+P+  
Sbjct: 1267 YSRADLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPKPNVK--WYKDGKPLRD 1324

Query: 1490 GHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            G R             ++    ED+G+Y C A N VG
Sbjct: 1325 GPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVG 1361



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 20/65 (30%), Positives = 29/65 (44%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            +P   V WY +G  L+   R      +    L +    P+D+G Y C A N  G A  T 
Sbjct: 2152 NPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTV 2211

Query: 3509 SMKVQ 3513
             +KV+
Sbjct: 2212 MVKVE 2216



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 3/99 (3%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P F+T +     + E +     C+++  G P   + WF +  P+   NR    Y+    A
Sbjct: 2224 PSFITGL-FPVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSA 2280

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
            +    +   D+G Y C ATN  G   + A +    K  I
Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAI 2319



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 6/70 (8%)

Query: 2669 RTDPNLKIEWFKNG--VTLTTGARLKSTFD-FGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            R  P   + W K+G  ++ + G  L+   + + LV + +     +DSG YTC+A + LG+
Sbjct: 2442 RGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTK---EDSGNYTCQAVSSLGK 2498

Query: 2726 AVSTASIKIE 2735
            A  +  +K+E
Sbjct: 2499 ASQSFDLKVE 2508



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 5/109 (4%)

Query: 3409 DTSVEEEKGKA--PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
            D  VE  K K   P F   L  ++ +REG       ++  T D   K+EW  +G++   G
Sbjct: 2504 DLKVEAPKVKEEPPSFLSELPPLQ-VREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPG 2560

Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
                   D   + L       +D+G Y C   N +GE+ ++A + +  K
Sbjct: 2561 GNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 5/101 (4%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            DK   P F  ++Q  T + E E    + ++   G P   VEW  +G+ +   +R    +D
Sbjct: 22   DKGTIPEFTKKLQPVT-VREGERISLDARVK--GKPTPTVEWMVDGEKVQDDHRIKTTFD 78

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMD--ETKAVIKTT 4066
                 +       +D GEY C ATN  G     T+ ++K T
Sbjct: 79   GERCTLKIMPSERDDEGEYKCVATNEVGQATITTEVLVKET 119



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 23/95 (24%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 1567 TDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF 1626
            T+++ + T + P     ++ +++ EG    F+ R+      T KVEW+ N   + +  RF
Sbjct: 112  TEVLVKETLRKPEFKQKMQPLQVLEGDEVRFDVRID--GKPTPKVEWFKNRTKIDNEGRF 169

Query: 1627 TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
               +     +L I      D+ TY C A +  G++
Sbjct: 170  EIIDEEDLYSLIIDDTRLSDADTYKCIATSEAGKS 204



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 49/215 (22%), Positives = 79/215 (36%), Gaps = 37/215 (17%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            I++ EG  +    RV   G P   I W  + +P     R+ T        L +      D
Sbjct: 228  INITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPED 285

Query: 3765 AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEP 3824
            +G Y C A ++ G        T S + D+ +E   P+G++ +  K LE   I +      
Sbjct: 286  SGRYKCTAKSEHG--------TASKEFDVNVEKAKPKGVAPKFTKPLETLEIME------ 331

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
                                E  R EC V    +P    EW +  + L    R +   D 
Sbjct: 332  -------------------KETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDK 370

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
              V L++ +V  +D   Y   A N+ G   ++A +
Sbjct: 371  DSVVLEVRHVELDDEALYKVVAKNESGVATSEAEL 405



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF- 1098
            T+KP F    +    ++EG     +ARV  + +   TV+W+   +++    R     D  
Sbjct: 411  TEKPFFKKTPQNVT-VLEGDEIRLDARVGGKPE--PTVDWFKGDQKVAEEGRFLIVDDEE 467

Query: 1099 -GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                +L I + +  DSGVY   A N  G+A   A + +E
Sbjct: 468  GDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIE 506



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P  + PL ++   E     FE +I   G+P  ++ W      +   + +  +   G  + 
Sbjct: 1736 PVIVKPLSNLQVEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNHTF 1793

Query: 697  DMLSLNIQ--DSGEYTCRAVSATGVAETKAVLHVTPR 731
             ++  + Q  DSG Y C AV+  G A ++A L VT R
Sbjct: 1794 TLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGR 1830



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 8/84 (9%)

Query: 2380 QPLQNIDNIQ--EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG-YV-S 2435
            QP+  I +I+  EG  A FD      G+P  KVEW   E+ I    +   + + G Y+ S
Sbjct: 2029 QPIGMIRDIEGYEGGQARFDVHF--TGNP--KVEWLHGEEQIIHGEKYKISENPGEYLYS 2084

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            + +  ++ ED G Y C ASN  G+
Sbjct: 2085 LVVGDLKHEDGGRYTCVASNESGD 2108



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG-YV-ALNMKY 1774
            ++DI   E   A F+      G+PK  VEWL     I    +     + G Y+ +L +  
Sbjct: 2034 IRDIEGYEGGQARFDVHF--TGNPK--VEWLHGEEQIIHGEKYKISENPGEYLYSLVVGD 2089

Query: 1775 VNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            +  ED G YTC A NE G+A   + L V+ K
Sbjct: 2090 LKHEDGGRYTCVASNESGDATLHANLNVKDK 2120



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 9/106 (8%)

Query: 1304 DITVMQA---PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
            DI++ Q    P+    L +IE+VEG     +  +        +V+W+  G  I  G R++
Sbjct: 2603 DISITQKTRKPEAIAPLKSIESVEGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYK 2660

Query: 1361 PAYEFD----YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                 D       L + S+   DSG Y C ATN+ G       L+V
Sbjct: 2661 IIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKV 2706



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729
            P  ++EWFK    +    R     D   G+  L I   + +DSG+Y C   N +GE  + 
Sbjct: 1504 PTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFNDIGETQTK 1563

Query: 2730 ASIKIE 2735
            A ++++
Sbjct: 1564 AKLQVD 1569



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/87 (25%), Positives = 41/87 (47%), Gaps = 5/87 (5%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            +PV  +PL N+  ++E     F+ ++   G+P  +V W+     + + +      D G  
Sbjct: 1735 KPVIVKPLSNLQ-VEEKSLTRFEVQI--AGNPKPRVAWYHGTTKLIEGTIYKMLEDSGNH 1791

Query: 2435 SMT--ISHVRDEDEGVYMCRASNLLGE 2459
            + T  ++  +  D GVY C A N  G+
Sbjct: 1792 TFTLIVNDSQRHDSGVYKCVAVNEAGK 1818



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576
            P E++EG       ++     P+  FEW  NG  +++ +R + + D  + TL   +    
Sbjct: 1940 PVEVFEGNEVSLVCKLSAEAKPT--FEWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIE 1997

Query: 2577 DAGLYMCKAINRAG 2590
            D G Y C A N  G
Sbjct: 1998 DQGTYSCLAKNVFG 2011



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 7/105 (6%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V +   +P+    I+D I   EGG A F+           +VEWL     +    +    
Sbjct: 2021 VKKKGNRPQPIGMIRD-IEGYEGGQARFDVHFT----GNPKVEWLHGEEQIIHGEKYKIS 2075

Query: 962  FNFG-YV-ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
             N G Y+ +L +  +   D G YTC A N  G AT  ANL +  K
Sbjct: 2076 ENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNVKDK 2120



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 7/101 (6%)

Query: 764  EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
            ++   RPQ I  ++D+ E  EG  A F+   T   +P  +VEW      I    +     
Sbjct: 2022 KKKGNRPQPIGMIRDI-EGYEGGQARFDVHFT--GNP--KVEWLHGEEQIIHGEKYKISE 2076

Query: 824  NFG-YV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            N G Y+ SL +  L+ ED G YT  A N+ G+A   A++ V
Sbjct: 2077 NPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHANLNV 2117



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 2/74 (2%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            Q++EG  +  + +++ K  P  K+EW+ N   ++   RF++  +    +L + D    D+
Sbjct: 133  QVLEGDEVRFDVRIDGKPTP--KVEWFKNRTKIDNEGRFEIIDEEDLYSLIIDDTRLSDA 190

Query: 2982 GIYTCKAYNKRGEA 2995
              Y C A ++ G++
Sbjct: 191  DTYKCIATSEAGKS 204



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 18/59 (30%), Positives = 30/59 (50%)

Query: 2532 VVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            V  +G+P    +W+ +G  ++  SR          TL+I++    DAG Y C+A N+ G
Sbjct: 845  VTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMG 903



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 1036 EVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRI 1092
            ++K+ +K   P F+G       + +G+     A++  +      V+WY +GK +    R 
Sbjct: 1271 DLKVKEKDCAPEFVGDQAAPIVVRQGEDIDIGAQITAKPK--PNVKWYKDGKPLRDGPRT 1328

Query: 1093 QTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                        + S + ED+G+Y   A NA G+A  +  + VE
Sbjct: 1329 TIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKATRTFDVQVE 1372



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 20/65 (30%), Positives = 30/65 (46%)

Query: 668  MKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLH 727
            +K+EWLK+ + I         F  G  +L +  +  QD G Y C+  +  G A   A L 
Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728

Query: 728  VTPRA 732
            V  +A
Sbjct: 1729 VNEKA 1733



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 2944 KIEWYFNGKVLEQGSRFKLTSDFGFVTLDLV--DVYERDSGIYTCKAYNKRGEA 2995
            K+EW    + +  G ++K++ + G     LV  D+   D G YTC A N+ G+A
Sbjct: 2056 KVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDA 2109



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 3/92 (3%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P FV  ++ +T  +E    + + ++   G P   VE++ +   ++   R   + D    +
Sbjct: 2320 PTFVVGLK-ETEGLESSDMRLDVKIG--GFPRPTVEFYKDYDLIVDSERHKILEDGDRCS 2376

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064
            +    + PED+G Y C  TNL G++ ++AVI+
Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIR 2408



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 22/83 (26%), Positives = 36/83 (43%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+F       +V   EG         +  P+  + W ++G ++ S +           SL
Sbjct: 2416 PRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSSNGVSLRQRGESYSL 2475

Query: 3890 DILYVYAEDSGEYICRAVNDFGE 3912
             I+ V  EDSG Y C+AV+  G+
Sbjct: 2476 VIIKVTKEDSGNYTCQAVSSLGK 2498



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 5/105 (4%)

Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
           E +  + +++P F +  Q++  L EG     +A++    +PT  V+W+K  + +    R 
Sbjct: 404 ELLVNEATEKPFFKKTPQNVTVL-EGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRF 460

Query: 820 TSIFNF--GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             + +      SL I + +  D+G Y  +A N  G+A + A I++
Sbjct: 461 LIVDDEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 505



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165
            P FVS    V V EG      C+++   KP   W  NG+ +   +R + ++DG Y
Sbjct: 1932 PRFVSELRPVEVFEGNEVSLVCKLSAEAKPTFEWSRNGSPVRLDNRVQASFDGRY 1986



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/61 (36%), Positives = 31/61 (50%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            TV W  +G  I+S+N +         +L I  V  EDSG YT  A ++ G+A  S  + V
Sbjct: 2448 TVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQSFDLKV 2507

Query: 1136 E 1136
            E
Sbjct: 2508 E 2508



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/119 (21%), Positives = 45/119 (37%), Gaps = 2/119 (1%)

Query: 3794 VLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRV 3853
            + E++L      + +   + G +    +        P F  ++K   VEE +  R + RV
Sbjct: 690  IKETRLDDNTEYQVVIRNDIGSVKSETRVRITALVRPDFTKKLKPVEVEEGQEARLDVRV 749

Query: 3854 EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
                 P   +EW+     L    RY  + +    +L I     +D   Y C A N  G+
Sbjct: 750  VGTPTPN--VEWFCGTTKLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGK 806



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 10/81 (12%)

Query: 2406 PTLKVEWFRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXX 2464
            P   V+W+++ K + D  R T +  D  Y    +S  + ED G+Y C A+N +G+     
Sbjct: 1309 PKPNVKWYKDGKPLRDGPRTTIRARDDLYNCKVLS-AKPEDTGMYKCEATNAVGK----- 1362

Query: 2465 XXXXXXXXXIQLETQHPEGMK 2485
                     +Q+E   P G K
Sbjct: 1363 ---ATRTFDVQVEVPKPRGSK 1380



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 4/132 (3%)

Query: 1942 IIRDSQ-HESALEK-IQYLEDDSRYKRAVQDDSFVVEKPQFGKP-IKNAEVTEGHPVHLE 1998
            I+ DSQ H+S + K +   E      +A  + +     P F +  +K+A    G    + 
Sbjct: 1796 IVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDEVKDAVYVRGGQ-EVS 1854

Query: 1999 ATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV 2058
              LT    PT  V WY + + +Q+    K         L I  A   D+G Y C A N  
Sbjct: 1855 LMLTINGFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVAKNTH 1914

Query: 2059 GEAVTTSSVKVD 2070
            G    T  V+V+
Sbjct: 1915 GSVSRTFDVRVE 1926



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 2/102 (1%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            ++ EG  + L  ++  +  P    EW  NG  +   +R + + D  + TL  ++    D 
Sbjct: 1942 EVFEGNEVSLVCKLSAEAKPTF--EWSRNGSPVRLDNRVQASFDGRYSTLKFLNAKIEDQ 1999

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023
            G Y+C A N  G A + + +    K N  +     +  EG E
Sbjct: 2000 GTYSCLAKNVFGSASSQAKLLVKKKGNRPQPIGMIRDIEGYE 2041



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 14/55 (25%), Positives = 28/55 (50%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            G+P   V W+++   ++ + R+  +  +    +T+     +D G+Y C A N LG
Sbjct: 2151 GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLG 2205



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 22/97 (22%), Positives = 43/97 (44%), Gaps = 2/97 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            + P F   L  ++  EG    L  ++    D   ++EW  +G+    G     +++   +
Sbjct: 2515 EPPSFLSELPPLQVREGFEFKLIFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNI 2572

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
             L   +   +D+G Y C  TN+ GE+ +S  + +  K
Sbjct: 2573 TLAFKNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 5/98 (5%)

Query: 1464 FECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
            FE KL  + VT  + K+EW K+G+  T G       D   + L   +   +D+G Y C  
Sbjct: 2532 FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIV 2591

Query: 1522 VNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLE 1559
             N  G    S  +   S T   R  +  A L+ I+ +E
Sbjct: 2592 TNKFGESSSSADI---SITQKTRKPEAIAPLKSIESVE 2626



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 2/72 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EGD +     V     P +K  W  ++KP+    R  +T       L ++    EDSG Y
Sbjct: 232  EGDELDLSVRVRGKPKPEIK--WTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRY 289

Query: 2847 TCKATNSKGSAT 2858
             C A +  G+A+
Sbjct: 290  KCTAKSEHGTAS 301



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 52/230 (22%), Positives = 84/230 (36%), Gaps = 24/230 (10%)

Query: 3379 NLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVE-EEKGKAPVFTVPLSNIENLREGEN 3437
            +LI+ +  P  ++ G+   Q   D+     +  ++ EE   AP F    +    L E ++
Sbjct: 472  SLIIGNAKP--LDSGVYICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDD 529

Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRA 3497
               E  +T    P  +V W  + K L    R          I++I    P DSG Y C A
Sbjct: 530  MTLELHVTGKPKP--EVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEA 587

Query: 3498 YNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP 3557
             N  G  V T +  V       +E     G+   I  I  +         +  +  +G  
Sbjct: 588  KNKAG--VNTRTFIVN------VEVLFVAGISQVIGSIRFI---------VLAKKPAGEA 630

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK 3607
            PE T +  ++   E +     C+       +   EWF    P+  G R K
Sbjct: 631  PEITESLQEMEELEGNPVTLTCKF--TGTPAPVAEWFKASTPVRDGRRYK 678



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 17/63 (26%), Positives = 29/63 (46%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P  +++W KD +P+    R+   ++     L       ED   Y V A N+LG   ++A 
Sbjct: 1408 PQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAE 1467

Query: 860  IRV 862
            + V
Sbjct: 1468 LLV 1470



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 4097 TPEQVVEESKARCPPVF--VSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154
            T E V+   +    P F    L  +VT +EG        + G P+P V W+ +GN I + 
Sbjct: 2402 TSEAVIRVQEREHAPRFDGTDLGQSVTAQEGFELNKTFIIRGKPRPTVTWMKDGNVISSS 2461

Query: 4155 SRYKLTYDG-MYHFDIPKTRQYDTG 4178
            +   L   G  Y   I K  + D+G
Sbjct: 2462 NGVSLRQRGESYSLVIIKVTKEDSG 2486



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            +TEG  + L   +     P   ++W  + +P+++  R  TT       L +  A  ED+G
Sbjct: 230  ITEGDELDLSVRVR--GKPKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSG 287

Query: 2049 TYMCKATNAVGEAVTTSSVKVD 2070
             Y C A +  G A     V V+
Sbjct: 288  RYKCTAKSEHGTASKEFDVNVE 309



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/96 (23%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P    PKF T+  +  +++E ++A  E  +    +P    EW    + L    R +   D
Sbjct: 313  PKGVAPKF-TKPLETLEIMEKETARLECTVT--GEPAPTTEWLKGDQPLKETQRIKIERD 369

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
               V+L++ +   ++   Y+ VA N+ G  +++A L
Sbjct: 370  KDSVVLEVRHVELDDEALYKVVAKNESGVATSEAEL 405



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 31/109 (28%), Positives = 43/109 (39%), Gaps = 4/109 (3%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            KP F   L  P  V+E      E R    G P   VEWF     +    RF+   +    
Sbjct: 1184 KPDFKTKLK-PMEVTEESVAKFEVR--STGFPQPEVEWFLGSTKIEDSGRFRVVSEQDRH 1240

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQA 1284
             L I      D G Y     N  G+A++ A ++V E+ D   +   +QA
Sbjct: 1241 ELIISDVKVKDAGTYKCTLANQAGTAYSRADLKVKEK-DCAPEFVGDQA 1288



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 17/55 (30%), Positives = 27/55 (49%)

Query: 666  PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            P   ++W K+G+ +    R T   R    +  +LS   +D+G Y C A +A G A
Sbjct: 1309 PKPNVKWYKDGKPLRDGPRTTIRARDDLYNCKVLSAKPEDTGMYKCEATNAVGKA 1363



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 17/59 (28%), Positives = 28/59 (47%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            V W KDG  ++ + R+     +    LT+      DAG Y C A N +G A+ +  + +
Sbjct: 2157 VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKV 2215



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 4/105 (3%)

Query: 3412 VEEEKGKA-PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            VEE KG+  P F   L  ++ ++EG+      R++    P   + W+ +   +   +R  
Sbjct: 2215 VEELKGRGVPSFITGLFPVQ-IKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVV 2271

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
               +     LE+      D+G Y C A N+ G   ++A + ++ K
Sbjct: 2272 ASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRK 2316



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 31/153 (20%), Positives = 63/153 (41%), Gaps = 8/153 (5%)

Query: 1787 AINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRF 1846
            ++ + GE+ +   + V  + S     Q  S+L K  Q      +  + +      + P F
Sbjct: 2465 SLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQ-----SFDLKVEAPKVKEEPPSF 2519

Query: 1847 ITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI 1906
            +++L  P ++ EG    ++   +     + ++EW  +G+    G     S D     L  
Sbjct: 2520 LSELP-PLQVREG--FEFKLIFKVVTTKDSKIEWRKDGRAFTPGGNSEFSFDGRNITLAF 2576

Query: 1907 LTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
                 +D+G Y C   N  G++ SS  +++  K
Sbjct: 2577 KNATLKDAGRYQCIVTNKFGESSSSADISITQK 2609



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 6/73 (8%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR----TTHDFGFVTLDINSVVAND 2577
            EG  A ++  +     P  + +WY  G ++  G R++    T  D    TL I S+   D
Sbjct: 2626 EGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYKIIQSTDGDRPVYTLIIESLKYTD 2683

Query: 2578 AGLYMCKAINRAG 2590
            +G Y C A N  G
Sbjct: 2684 SGTYKCIATNEGG 2696



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/71 (29%), Positives = 28/71 (39%), Gaps = 2/71 (2%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS--YVSLDITHTYEEDSGIYTCKATNS 2853
            N + S  PT ++EWF     +    R+    D       L I     EDSG+Y C   N 
Sbjct: 1497 NTQVSGTPTPEVEWFKGESIVEDKGRFMIIDDAKEGVFQLVIEDAKPEDSGVYKCVVFND 1556

Query: 2854 KGSATTSGSLR 2864
             G   T   L+
Sbjct: 1557 IGETQTKAKLQ 1567



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 17/64 (26%), Positives = 29/64 (45%)

Query: 2274 LRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMT 2333
            +++E+  + K +         F  G  +L ++H V +D G Y  K  N LG  T   ++ 
Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLGSATCGANLI 1728

Query: 2334 VTAK 2337
            V  K
Sbjct: 1729 VNEK 1732



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 6/115 (5%)

Query: 1027 SRYSKRTEEEVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNG 1083
            S+ S  +  EV I +K   P F+  LK T  +   +S+     V+       TVE+Y + 
Sbjct: 2301 SQGSTSSSAEVTIKRKDAIPTFVVGLKETEGL---ESSDMRLDVKIGGFPRPTVEFYKDY 2357

Query: 1084 KQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
              I  + R +   D    +L I ++R ED+G Y  V  N  G     A + V+ R
Sbjct: 2358 DLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQER 2412



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 38/221 (17%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P FV   K  E  +E   +  + K+         VE++K+   +    R + + D    +
Sbjct: 2320 PTFVVGLKETEG-LESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            L I +L  ED+G Y C   NL         L   ++  ++R          +Q  E   +
Sbjct: 2377 LIITNLRPEDAGTYKCVITNL---------LGVETSEAVIR----------VQEREHAPR 2417

Query: 1564 YHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSG 1623
            +  TD+   VT Q       L    I  G+         P       V W  +   + S 
Sbjct: 2418 FDGTDLGQSVTAQEGF---ELNKTFIIRGKPR-------PT------VTWMKDGNVISSS 2461

Query: 1624 SRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            +  +        +L I+    EDSG YTC+A+++LG+A  S
Sbjct: 2462 NGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQS 2502



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 30/124 (24%), Positives = 50/124 (40%), Gaps = 10/124 (8%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKL--EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            + P+F T+P     ++E +    EC +  EP   +    EW K  QP+    R +   D 
Sbjct: 316  VAPKF-TKPLETLEIMEKETARLECTVTGEPAPTT----EWLKGDQPLKETQRIKIERDK 370

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD---IVRSTQNEAGLEQIQ 1556
              V L++  +  +D  +Y   A N  G       L     T+     ++ QN   LE  +
Sbjct: 371  DSVVLEVRHVELDDEALYKVVAKNESGVATSEAELLVNEATEKPFFKKTPQNVTVLEGDE 430

Query: 1557 VLED 1560
            +  D
Sbjct: 431  IRLD 434



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 5/98 (5%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            + E P F    Q+VT L EG     +AR+    +P   V+WF   +K+    R+    D 
Sbjct: 410  ATEKPFFKKTPQNVTVL-EGDEIRLDARVGGKPEPT--VDWFKGDQKVAEEGRFLIVDDE 466

Query: 3338 GIVILDILYCYEE--NSGEYECVATNKLGRDSTKANLK 3373
               +  ++    +  +SG Y C ATN  G+ + +A ++
Sbjct: 467  EGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQ 504



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 2/82 (2%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA--TVSCKLQ 3648
            V W+ + K L     VK I       L I      D+G+Y C A N HG    T   +++
Sbjct: 1867 VMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFDVRVE 1926

Query: 3649 VKGRQGIILEPQLPSHFKSGTE 3670
            V G+    +    P     G E
Sbjct: 1927 VDGKAPRFVSELRPVEVFEGNE 1948



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 4/110 (3%)

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            + TLH    + ++D+   P     +  + I V  G  ++    +   G+P   ++W+ +G
Sbjct: 2108 DATLHAN--LNVKDKHIAPMFVEDDTGEPITVEAGKELNVIMNIR--GNPRPDVNWYKDG 2163

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
                   R+   + +    L +      DAG Y C A NK G+A+ T  +
Sbjct: 2164 SFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMV 2213



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/65 (30%), Positives = 30/65 (46%)

Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264
            G P   V W  +G  ++  +           +L II  T  D+G YT +AV+ LG A  S
Sbjct: 2443 GKPRPTVTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKEDSGNYTCQAVSSLGKASQS 2502

Query: 1265 AIVRV 1269
              ++V
Sbjct: 2503 FDLKV 2507



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022
            D+    K + P  +  ++S  S VE    +F+ +++    P  KV+W+  G  + H  R+
Sbjct: 2603 DISITQKTRKPEAIAPLKSIES-VEGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRY 2659

Query: 4023 TPIY----DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064
              I     D     +    +   DSG Y C ATN  G+   K+ +K
Sbjct: 2660 KIIQSTDGDRPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLK 2705



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 7/100 (7%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK----TYYD 1231
            KP  + PL +   V EG     +  +     P  +V+W+H G  +T G R+K    T  D
Sbjct: 2612 KPEAIAPLKSIESV-EGGQARFDVEMSAF--PLPKVDWYHGGTKITHGGRYKIIQSTDGD 2668

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
                 L I      D+G Y   A N  G     + ++V E
Sbjct: 2669 RPVYTLIIESLKYTDSGTYKCIATNEGGVTTIKSDLKVKE 2708



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 33/133 (24%), Positives = 54/133 (40%), Gaps = 5/133 (3%)

Query: 2606 IIDQAMRPES--WEQIQLKEAAMNKVPEMFVDTGVQQAPIFTT-HLKSYDKLVEGQHVYL 2662
            I++ + R +S  ++ + + EA           TG   AP F    +K    +  GQ V L
Sbjct: 1796 IVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFVEDEVKDAVYVRGGQEVSL 1855

Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNL 2722
               +     P+  + W+K+   L     +K      +  L I     +DSGIY C A N 
Sbjct: 1856 MLTINGFPTPD--VMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVAKNT 1913

Query: 2723 LGEAVSTASIKIE 2735
             G    T  +++E
Sbjct: 1914 HGSVSRTFDVRVE 1926



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 5/83 (6%)

Query: 4124 EGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY---DGMYHFDIPKTRQYDTGKI 4180
            EG  ARF    TG+PK  V WL     I++G +YK++    + +Y   +   +  D G+ 
Sbjct: 2041 EGGQARFDVHFTGNPK--VEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRY 2098

Query: 4181 EVIXXXXXXXXXXXXXLKVIPRH 4203
              +             L V  +H
Sbjct: 2099 TCVASNESGDATLHANLNVKDKH 2121



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/98 (22%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F+  +++ T+ +E      + ++     P   VE++ +   +    R++   D     
Sbjct: 2320 PTFVVGLKE-TEGLESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILEDGDRCS 2376

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKEN 3379
            L I     E++G Y+CV TN LG ++++A ++   +E+
Sbjct: 2377 LIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREH 2414



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 19/62 (30%), Positives = 29/62 (46%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P   +E++ +   +    R+K   D    SL IT+   ED+G Y C  TN  G  T+   
Sbjct: 2347 PRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAV 2406

Query: 2863 LR 2864
            +R
Sbjct: 2407 IR 2408



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 2/88 (2%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            ++  +EG  ++    +     PT  + W  +   + S             SL I    +E
Sbjct: 2426 SVTAQEGFELNKTFIIRGKPRPT--VTWMKDGNVISSSNGVSLRQRGESYSLVIIKVTKE 2483

Query: 2842 DSGIYTCKATNSKGSATTSGSLRCTGDK 2869
            DSG YTC+A +S G A+ S  L+    K
Sbjct: 2484 DSGNYTCQAVSSLGKASQSFDLKVEAPK 2511



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 26/127 (20%), Positives = 56/127 (44%), Gaps = 6/127 (4%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRT-DMVDE---VTTQAPICTTSLKNVEIKEGQRAHF 1597
            I++ T+ ++G    Q +    K  ++ D+  E   V  + P   + L  ++++EG     
Sbjct: 2477 IIKVTKEDSGNYTCQAVSSLGKASQSFDLKVEAPKVKEEPPSFLSELPPLQVREGFEFKL 2536

Query: 1598 ERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINA 1657
              +++   D+  K+EW  + +    G     + +   + L   +   +D+G Y C   N 
Sbjct: 2537 IFKVVTTKDS--KIEWRKDGRAFTPGGNSEFSFDGRNITLAFKNATLKDAGRYQCIVTNK 2594

Query: 1658 LGEAVTS 1664
             GE+ +S
Sbjct: 2595 FGESSSS 2601



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 17/63 (26%), Positives = 29/63 (46%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P   ++W KD +PI  + R+T+        L +   + ED+G Y   A ++ G A     
Sbjct: 246 PKPEIKWTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSEHGTASKEFD 305

Query: 860 IRV 862
           + V
Sbjct: 306 VNV 308



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 2/74 (2%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576
            P ++ EG       RV   G P     W+ +   +   +R   +++     L++  +  +
Sbjct: 2232 PVQIKEGDKYTLVCRVS--GKPKPTITWFRDNTPVHTDNRVVASYEGSVSALELKEMKLS 2289

Query: 2577 DAGLYMCKAINRAG 2590
            DAGLY C A N  G
Sbjct: 2290 DAGLYKCTATNSQG 2303



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 15/51 (29%), Positives = 22/51 (43%)

Query: 4005 MKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            +KVEW  + KP+         +  G   +    V  +D G Y C+ TN  G
Sbjct: 1669 VKVEWLKDDKPIAKDRHLKEAFHNGVCTLILKHVVQQDKGVYKCKVTNKLG 1719



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 46/197 (23%), Positives = 75/197 (38%), Gaps = 13/197 (6%)

Query: 1408 LILESQHPSGLEKIQYLEDTSRYKKTDIIDESV---TIKPRFVTRPKSIENVIEGQHVHF 1464
            LI++    S  +  + +  +   K T I++ SV   T  P        I N+ EG  +  
Sbjct: 180  LIIDDTRLSDADTYKCIATSEAGKSTCIVELSVKEKTSAPEVFGDTAPI-NITEGDELDL 238

Query: 1465 ECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNL 1524
              ++       +K  W K+ +P+    R           L + D   EDSG Y C A + 
Sbjct: 239  SVRVRGKPKPEIK--WTKDDKPIKKTDRLTTTTKDDECVLVLSDAKPEDSGRYKCTAKSE 296

Query: 1525 VGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTS- 1583
             GT      +          + +    LE ++++E       T  ++   T  P  TT  
Sbjct: 297  HGTASKEFDVNVEKAKPKGVAPKFTKPLETLEIME-----KETARLECTVTGEPAPTTEW 351

Query: 1584 LKNVE-IKEGQRAHFER 1599
            LK  + +KE QR   ER
Sbjct: 352  LKGDQPLKETQRIKIER 368



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDF-- 2563
            EKP F +     + L EG     +ARV   G P    +W+    ++    RF    D   
Sbjct: 412  EKPFFKKTPQNVTVL-EGDEIRLDARVG--GKPEPTVDWFKGDQKVAEEGRFLIVDDEEG 468

Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590
               +L I +    D+G+Y+C+A N  G
Sbjct: 469  DLFSLIIGNAKPLDSGVYICQATNDTG 495



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/87 (22%), Positives = 35/87 (40%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP+     ++  +   E       V    +P+  ++W+++GK +    R          +
Sbjct: 821  PPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYT 880

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFT 3915
            L+I     ED+G Y C A N  G   T
Sbjct: 881  LNIHTTEPEDAGSYTCEAQNKMGTSST 907



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 2/95 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P     LK VT   G       +I   G P  KI+W+K+ + ++   R    +      L
Sbjct: 1381 PSLEAELKPVTVTAGEDTKLVCKIS--GKPQPKIDWMKDDKPLKPDKRVLPTYDGETCVL 1438

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
                  ++D  EY   A +  G   T A L V  +
Sbjct: 1439 TFHKAVLEDEAEYKVVAKNELGSVSTSAELLVNEK 1473



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 17/66 (25%), Positives = 30/66 (45%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  KI+W K+   L    R+  T+D     L+ +    +D   Y   A N LG   ++A 
Sbjct: 1408 PQPKIDWMKDDKPLKPDKRVLPTYDGETCVLTFHKAVLEDEAEYKVVAKNELGSVSTSAE 1467

Query: 2732 IKIEDR 2737
            + + ++
Sbjct: 1468 LLVNEK 1473



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 35/145 (24%), Positives = 51/145 (35%), Gaps = 4/145 (2%)

Query: 3640 EATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE-DEKPNPPRFT 3698
            E T+   L+  G     L         SG      + E      + T+E   +P  P F 
Sbjct: 1778 EGTIYKMLEDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEVTGRPCAPTFV 1837

Query: 3699 V-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDI 3757
              E+KD + V  G  V     +   G PT  + W+ + +       V  +       L I
Sbjct: 1838 EDEVKDAVYVRGGQEVSLMLTIN--GFPTPDVMWYKDDKELQESQLVKIIPKGNMYYLII 1895

Query: 3758 DYIYARDAGEYTCRATNKWGSATTT 3782
                  D+G Y C A N  GS + T
Sbjct: 1896 YKASLNDSGIYRCVAKNTHGSVSRT 1920



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/66 (30%), Positives = 29/66 (43%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            PT  + W+ ++K L      K     +   L I      DSGIY C A N+ GS + +  
Sbjct: 1863 PTPDVMWYKDDKELQESQLVKIIPKGNMYYLIIYKASLNDSGIYRCVAKNTHGSVSRTFD 1922

Query: 2863 LRCTGD 2868
            +R   D
Sbjct: 1923 VRVEVD 1928



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            E+TI+  K   P F V +K+   + E   +  D ++   G P   ++++ +        R
Sbjct: 2310 EVTIK-RKDAIPTFVVGLKETEGL-ESSDMRLDVKIG--GFPRPTVEFYKDYDLIVDSER 2365

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               L D    +L I  +   DAG Y C  TN  G  T+ A I
Sbjct: 2366 HKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVI 2407



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 3/104 (2%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            + K   P F V L   E L E  +   + ++     P   VE+Y +   +    R +   
Sbjct: 2314 KRKDAIPTFVVGLKETEGL-ESSDMRLDVKIGGFPRPT--VEFYKDYDLIVDSERHKILE 2370

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
            D     L I+   PED+G Y C   N  G   + A ++VQ + +
Sbjct: 2371 DGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREH 2414



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP  T  L+ +EI E + A  E  +    +     EW   ++PLK   R     +   V 
Sbjct: 317  APKFTKPLETLEIMEKETARLECTV--TGEPAPTTEWLKGDQPLKETQRIKIERDKDSVV 374

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            L++     +D   Y   A N  G A +    +V+
Sbjct: 375  LEVRHVELDDEALYKVVAKNESGVATSEAELLVN 408



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 16/65 (24%), Positives = 28/65 (43%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P   + W K+G  ++ + R     R+    L +      D+G Y C A +  G A   
Sbjct: 2151 GNPRPDVNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRT 2210

Query: 724  AVLHV 728
             ++ V
Sbjct: 2211 VMVKV 2215



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 3/97 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P FIT +  V ++ EG       R+     P   + WF +   +   +R    ++  +  
Sbjct: 2224 PSFITGLFPV-QIKEGDKYTLVCRVSGKPKPT--ITWFRDNTPVHTDNRVVASYEGSVSA 2280

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            L++      ++G Y+C ATN  G  S+ A +    K+
Sbjct: 2281 LELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKD 2317



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 3/92 (3%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            KP      K +  V  G+     CK+        K++W K+ +P+    R  P +D    
Sbjct: 1380 KPSLEAELKPV-TVTAGEDTKLVCKISGKPQP--KIDWMKDDKPLKPDKRVLPTYDGETC 1436

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
             L     + ED   Y   A N +G+   S  L
Sbjct: 1437 VLTFHKAVLEDEAEYKVVAKNELGSVSTSAEL 1468



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E   KP    P+ + + ++E     FE ++   G+   RV W      +   +     
Sbjct: 1729 VNEKAVKPVIVKPLSN-LQVEEKSLTRFEVQIA--GNPKPRVAWYHGTTKLIEGTIYKML 1785

Query: 962  FNFGYVALT--IKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             + G    T  +     HD+G Y C A N  G+A + A L +
Sbjct: 1786 EDSGNHTFTLIVNDSQRHDSGVYKCVAVNEAGKAISQATLEV 1827



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 2/65 (3%)

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDII--DLIAEDSGIYTCRAVNLVGTDEVSC 1532
            N KVEW    + +  G +++   + G     ++  DL  ED G YTC A N  G   +  
Sbjct: 2054 NPKVEWLHGEEQIIHGEKYKISENPGEYLYSLVVGDLKHEDGGRYTCVASNESGDATLHA 2113

Query: 1533 RLTCR 1537
             L  +
Sbjct: 2114 NLNVK 2118



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/75 (24%), Positives = 30/75 (40%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            V WY +G  +    R+     +    L +     +D+G+Y   A+N  G A  +  + VE
Sbjct: 2157 VNWYKDGSFLQQTGRMGISSRWDSYRLTVFKAVPDDAGIYRCEAKNKLGTASRTVMVKVE 2216

Query: 1137 TRSSIDTSSIHRGLY 1151
                    S   GL+
Sbjct: 2217 ELKGRGVPSFITGLF 2231


>SB_8817| Best HMM Match : I-set (HMM E-Value=0)
          Length = 2526

 Score =  182 bits (442), Expect = 8e-45
 Identities = 125/422 (29%), Positives = 197/422 (46%), Gaps = 15/422 (3%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            E P +P+ P I TK++    V E        EF  E    + W ++   +       I T
Sbjct: 1886 EQPTEPAGPRI-TKELVDAEVEETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKT 1944

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
              T S L I +  V+D  ++     N+ G    SA ++VEE          PP F    +
Sbjct: 1945 DETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAV-ESEAEPPRFVTPLK 2003

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            +  +  G  V +  +  GT PI + W K+ K++ PD R+   ++   +T+ I     +D 
Sbjct: 2004 DQELEEGSTVDMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDE 2063

Query: 4582 GKY-ECVAINSAGEARCDAECVVSLP-ATKDKPKPQTKAANAP-PEIIEPLKDKI-VAEG 4637
              Y + VA N AGEA  DAE +V +  A +  P  +   A  P P II+PL D+I V EG
Sbjct: 2064 AMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEG 2123

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
             ++   C I G P   V WYK D L++  +        D++TL I  A  +DE +YKCV 
Sbjct: 2124 DSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVV 2183

Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
             N AG V V  +L V   ++  +LP +   L+D    EG   +F  ++  K +P ++W +
Sbjct: 2184 TNIAGSVDVKTELIV---EEGISLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPVVEWFK 2240

Query: 4757 EGALIPETPDFQMIHEGNNA-----VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               L+ ++  F +I + ++       L+I     ED   ++  A   AG+  +  KL+V 
Sbjct: 2241 NDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVN 2300

Query: 4812 SK 4813
            SK
Sbjct: 2301 SK 2302



 Score =  160 bits (389), Expect = 2e-38
 Identities = 116/416 (27%), Positives = 179/416 (43%), Gaps = 22/416 (5%)

Query: 4400 VVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI 4459
            +VE P      P F K ++   VFE +  R E    G P P I W +    +K       
Sbjct: 1153 IVEKP--EGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITT 1210

Query: 4460 HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT 4519
                   +L I    ++D   +  +A N  G A   A L+V E        +V P F  T
Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLVNE-------ALVKPKFIET 1263

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
              +  + +G+ V    K  G+   DV W      V    R  I  E+ T TL+I +  P 
Sbjct: 1264 THDTEIITGESVWFRVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPI 1323

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP---PEIIE-PLKDKIVA 4635
            D G Y+C+  N AGE     +  VS     +K KP T     P   P + E PLK   ++
Sbjct: 1324 DKGNYKCIISNDAGE-----DMTVSKLTVIEKKKPITDVGTPPEFSPHVGEGPLK---IS 1375

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            +G  +    KI G+P P +QW+K DK +KPS+  ++    D ++L I  A P+D   Y C
Sbjct: 1376 DGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTC 1435

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
             A N +G  T    + ++        P  + PL+   + E        + T    P +QW
Sbjct: 1436 KATNKSGTTTRNINVDISALMPEGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQW 1495

Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             +E   + E     +I E +++ L+I  T  +D G++    +   G+  + A+LVV
Sbjct: 1496 FKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVV 1551



 Score =  160 bits (388), Expect = 3e-38
 Identities = 106/394 (26%), Positives = 177/394 (44%), Gaps = 29/394 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E      E +  G     I WY+++ P+ +SP F+    +    L I  + ++D A +
Sbjct: 882  VVEGSSVTIECQSSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEY 941

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
                    G    +  L+VEE        ++ P      +++ +      R D +V G+ 
Sbjct: 942  RCDIATDRGVVSMTTELIVEE-------AVLMPVIIQPLKSLEIKEENAARFDVRVRGSP 994

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEE-----DGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
               V W K+G+++Q   R  I+++        Y+L+I +  P+D+G+YECVA+N AG+A 
Sbjct: 995  QPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKAT 1054

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
              A   V    TK     +T           P+      EG  I     + G P   V+W
Sbjct: 1055 STATLQV---LTKISELDKT-----------PVH---TVEGSDITMKVAVSGTPRTEVEW 1097

Query: 4657 YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
            YK D+ +   K + +  T D+Y L I+ A P D G YKCV  N +G  T    + + +  
Sbjct: 1098 YKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYKCVTKNDSGTFTQMFDITIVEKP 1157

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
            +      + PL+ + V+E QP + +  +T   +P I WL+ G ++ E      + +G   
Sbjct: 1158 EGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITTVFDGETC 1217

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            VL I  +  +D G + C A    G+  T A+L+V
Sbjct: 1218 VLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score =  151 bits (365), Expect = 2e-35
 Identities = 113/425 (26%), Positives = 181/425 (42%), Gaps = 32/425 (7%)

Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
            + T E +VE  V     P+  + ++   + E   ARF+V   G P PL++W+++   +++
Sbjct: 953  SMTTELIVEEAVLM---PVIIQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQD 1009

Query: 4454 SPDFQI---HTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGR 4508
               F I        K +  L+I  V  ED+  +  VA N  G A  +A L V  K  +  
Sbjct: 1010 LGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKISE-- 1067

Query: 4509 GGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568
                     L    V+   G  + +   V+GT   +V W K+ +K+       I      
Sbjct: 1068 ---------LDKTPVHTVEGSDITMKVAVSGTPRTEVEWYKDDRKLSNRKPYVIKTTVDD 1118

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            Y L I  A P D+G Y+CV  N +G      +  +      +KP+       A PE I+P
Sbjct: 1119 YELTITSASPSDAGTYKCVTKNDSGTFTQMFDITI-----VEKPE------GAAPEFIKP 1167

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            LK   V E Q +   C + G P P + W KG  ++K           +   L I+ +  +
Sbjct: 1168 LKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITTVFDGETCVLNITVSCLD 1227

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            DEG+YKC+A N  G+    A+L V +          T   D  +  G+   F+ +     
Sbjct: 1228 DEGEYKCLAMNDFGKAATVAELLVNEALVKPKFIETT--HDTEIITGESVWFRVKYEGSP 1285

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             P + W  E  L+ +T  F +  E + + L+I +    D G + C  +  AG+  T +KL
Sbjct: 1286 TPDVDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKL 1345

Query: 4809 VVKSK 4813
             V  K
Sbjct: 1346 TVIEK 1350



 Score =  149 bits (360), Expect = 7e-35
 Identities = 93/337 (27%), Positives = 158/337 (46%), Gaps = 17/337 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F +      +   E   F V+++G P P + WY E+  + ++  F I+T    S LII
Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTLII 1317

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSG 4528
              V   D   +  +  N  G     + L V EK++       PP F+  +    + ++ G
Sbjct: 1318 EDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTPPEFSPHVGEGPLKISDG 1377

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
              + L+ K+TG    ++ W K+ K V+P  + ++   D  ++L I+ A P D+ KY C A
Sbjct: 1378 GDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKA 1437

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N +G    +    +S         P+ +A    P+ +EPLK   + E  +   + K  G
Sbjct: 1438 TNKSGTTTRNINVDISALM------PEGEA----PKYVEPLKSDEIVEDSSFTMNVKFTG 1487

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
             P+P VQW+K +K ++      + R +D  TL I++  P+DEG YK V  N  G+    A
Sbjct: 1488 TPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEA 1547

Query: 4709 KLKVTQPDQADN---LPALTPL--RDIVVYEGQPAQF 4740
            +L V    +A++   +P +TP   +  +   GQ  +F
Sbjct: 1548 ELVVMTVSEAEDEGIIPKVTPTPGKTEITIPGQKPKF 1584



 Score =  148 bits (358), Expect = 1e-34
 Identities = 104/389 (26%), Positives = 169/389 (43%), Gaps = 25/389 (6%)

Query: 4419 PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDS 4478
            P    E      +V   G P   ++WY+++  + N   + I T      L I      D+
Sbjct: 1072 PVHTVEGSDITMKVAVSGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDA 1131

Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
              +  V +N  GT     ++ + EK  +G      P F    + + V   Q VRL+  VT
Sbjct: 1132 GTYKCVTKNDSGTFTQMFDITIVEKP-EGAA----PEFIKPLKVLEVFETQPVRLECSVT 1186

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
            GT    + WLK G  V+ D R   + +  T  L I  +   D G+Y+C+A+N  G+A   
Sbjct: 1187 GTPEPQITWLKGGDVVKEDDRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATV 1246

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            AE +V+    K             P+ IE   D  +  G+++ F  K  G P P V WY 
Sbjct: 1247 AELLVNEALVK-------------PKFIETTHDTEIITGESVWFRVKYEGSPTPDVDWYH 1293

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ- 4717
             D L+  +  F ++   D  TL I +  P D+G+YKC+  N AG     +KL V +  + 
Sbjct: 1294 EDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKP 1353

Query: 4718 ---ADNLPALTP---LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH 4771
                   P  +P      + + +G     + +IT + KP IQW ++   +  +   ++ +
Sbjct: 1354 ITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDY 1413

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
              +   L I     +DT  +TC+AT  +G
Sbjct: 1414 RDDIHSLTIVGASPDDTAKYTCKATNKSG 1442



 Score =  146 bits (353), Expect = 5e-34
 Identities = 160/710 (22%), Positives = 289/710 (40%), Gaps = 68/710 (9%)

Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTGK 4179
            + +EG+  R   +VTG P+P V W  +G  +      +L + +  Y   I +    D+G 
Sbjct: 187  STDEGD-VRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGS 245

Query: 4180 IEVIXXXXXXXXXXXXXLKV-----IPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKT 4234
                             + +      P+  + R +LK   RP +   +  +  E ++   
Sbjct: 246  YRCTLTSDVGKSTRTFSVDIESEGPAPKESEKRKLLKGEERPKFVSDSTVE--EFKITDE 303

Query: 4235 FEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESR 4294
             E R  ++  G        KP     PE EW +  K  K ++   ++   E +  I   R
Sbjct: 304  GELRLTVKVTG--------KPF----PEVEWTKDDKDLKEDD---RVIISEQDDGIVVLR 348

Query: 4295 LRE-STHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSES 4353
            +++   H   +   +V+S+    + +       D T E  E+R  KK+ +     D +E 
Sbjct: 349  IKDVGAHDSGVYKCQVSSDVGTSTKS------FDVTIE-GERRKAKKLIEV----DETE- 396

Query: 4354 TVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIF 4413
                   H+ K+ +  KE V ++++         T+++   Q +E  V+  +K     + 
Sbjct: 397  -------HLEKRIKHVKEPVPEEQVMPTKVKPVETKVDKPRQIEE--VDAMLKEEPTFLE 447

Query: 4414 TKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV 4473
            + +++P  V E    +   +  G+P P ++W++++ P+       I        L+I++ 
Sbjct: 448  SDEIKPFEVTEEGDIKMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEP 507

Query: 4474 FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV--NVTSGQLV 4531
              +D   +     N  G  + + ++ V++ R+      V P F      V    T    V
Sbjct: 508  TKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDV 567

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            RL  KVTG    +V W K+GK V      ++  ++  Y L I EA P DSG Y C   + 
Sbjct: 568  RLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSD 627

Query: 4592 AGEA-RCDAECVVSL-PATKDKPKPQTKAANAPPEII--EPLKD-KIVAEGQAIEFSCKI 4646
             G++ R  +  + S  PATK+  K + +     P+ +    L++ KI  EG+ +  + K+
Sbjct: 628  VGKSTRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGE-LRLTVKV 686

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-YTLRISEAFPEDEGDYKCVAYNSAGR-- 4703
             GKP P V+W K DK +K      +S   D    LRI +    D G YKC   +  G   
Sbjct: 687  TGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTST 746

Query: 4704 ----VTV------AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
                VT+      A KL       A +    T +    + +    +   ++  K +P  +
Sbjct: 747  KSFDVTIEGERRKAKKLIEVDDTVAPHFVEDTSIAPFELTDSGDVRLSVRVAGKPEPNFK 806

Query: 4754 WLREGALIP-ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            W ++   I   +  +      +   L++ +    D GT+ C AT   G V
Sbjct: 807  WTKDDEDIDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGGTV 856



 Score =  140 bits (340), Expect = 2e-32
 Identities = 134/466 (28%), Positives = 197/466 (42%), Gaps = 69/466 (14%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            +E     ++PP F   ++   + E       VE DG     IKW+++N  +   PD + H
Sbjct: 1986 LEAVESEAEPPRFVTPLKDQELEEGSTVDMLVETDGTSPIHIKWFKDNKELV--PD-ERH 2042

Query: 4461 TFS---TKSILIIRQVFVEDSAVF-AAVAENRGGTAKCSANLVVEEKR-------RQGRG 4509
            TF+    K  + I  V +ED A++   VAEN  G A   A ++VE K         +   
Sbjct: 2043 TFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTPVEEVVD 2102

Query: 4510 GIVPPSFTLTAQN--VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDG 4567
              VP    +   N  ++V  G  VRL+  ++G     V W K+   ++ D R     +  
Sbjct: 2103 AAVPAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGD 2162

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
             +TL+I  A   D  +Y+CV  N AG      E +V             +   + P I E
Sbjct: 2163 QHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIV-------------EEGISLPVIKE 2209

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE-----YTLRI 4682
             LKD    EG  + F  ++ GKP P V+W+K D+L+  S  F +    D+     ++L I
Sbjct: 2210 GLKDTEANEGDVVRFDIRVAGKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVI 2269

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ------PDQAD-NLPALTPL-------- 4727
                PED+  Y  VA N AG+ +   KL V        P QAD   P L PL        
Sbjct: 2270 EGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVP 2329

Query: 4728 ------------------RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
                              ++I V EG+ A+F   +    +P+I W R   LIP+   F  
Sbjct: 2330 EEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPSIDWYRGEELIPDEGRFVH 2389

Query: 4770 IHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            I      +  L+I NT   DTG +TC A     ++   A L VK K
Sbjct: 2390 IDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435



 Score =  136 bits (328), Expect = 5e-31
 Identities = 119/509 (23%), Positives = 208/509 (40%), Gaps = 30/509 (5%)

Query: 4331 EVTEQRVQKKVTQKPRIPDPS-----ESTVHGKEVHVAKQKQTQKEVVGDKEITRKITST 4385
            EVTE+   K   Q    P PS     +      + H+   ++     +  KE T+K   T
Sbjct: 455  EVTEEGDIKMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGT 514

Query: 4386 ETTEIEHKAQTQERVVEGPV--------KPSKPPIFTK--KMQPCRVFEHEQARFEVEFD 4435
             T E+ ++A    R  +  V        K +  P F +     P +  +    R  V+  
Sbjct: 515  YTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVT 574

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G+P P + W ++  P+   P+ ++     + IL IR+   +DS  +     +  G +  +
Sbjct: 575  GKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRT 634

Query: 4496 ANLVVEEK--------RRQGRGGIVPPSFTL--TAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
             ++ +E K        +++ R G   P F    T +   +T    +RL  KVTG    +V
Sbjct: 635  FSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGKPFPEV 694

Query: 4546 YWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
             W K+ K ++ D R  I E+D G   L I +    DSG Y+C   +  G +    +  + 
Sbjct: 695  EWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFDVTIE 754

Query: 4605 LPATKDKPKPQTKAANAPPEIIEP-LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
                K K   +     AP  + +  +    + +   +  S ++ GKP P  +W K D+ I
Sbjct: 755  GERRKAKKLIEVDDTVAPHFVEDTSIAPFELTDSGDVRLSVRVAGKPEPNFKWTKDDEDI 814

Query: 4664 K-PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
               S  +   R  D  TL +    P D+G YKC A N  G VT   ++ +   D    + 
Sbjct: 815  DFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQVNMEGIDTGPQIQ 874

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782
              +  ++I V EG     + Q +      I W ++   + ++P F+   +     L I +
Sbjct: 875  EYS--KEIEVVEGSSVTIECQSSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHD 932

Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               +D   + C   T  G V  + +L+V+
Sbjct: 933  IVIDDEAEYRCDIATDRGVVSMTTELIVE 961



 Score =  133 bits (321), Expect = 4e-30
 Identities = 99/336 (29%), Positives = 154/336 (45%), Gaps = 20/336 (5%)

Query: 250  VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
            V + TE+    G +S P I +  ++++  EG   +F ++++G P P V WFKN + L +S
Sbjct: 2190 VDVKTELIVEEG-ISLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPVVEWFKNDELLDDS 2248

Query: 310  NKHEIITTHNHT-----TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
             K  II   +       +L +      D   Y+++A N  G   + G L V S  E    
Sbjct: 2249 GKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAP 2308

Query: 365  DQRS------QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
             Q        + + +T     EE    S +  AP F++  ++ +V EG+  RFD  V G 
Sbjct: 2309 AQADAATPILEPLVETIPEVPEEEAA-SPETKAPVFIETMKNIEVMEGEEARFDVHVDGV 2367

Query: 419  PYPEVTWFINDRQIRDD--YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
            P P + W+  +  I D+  + H   V E     L+I N  L D+G  TC+A N   E   
Sbjct: 2368 PEPSIDWYRGEELIPDEGRFVHIDAVKEE-IFTLVIENTKLGDTGKYTCIAANDVDEITC 2426

Query: 477  QCRLNVIEKEQVVAPKFVER--FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534
            +  L V  KE  +AP+F +    ST +V  G+ V L+    G PTP++ W KD  P+   
Sbjct: 2427 EAVLTVKPKE--IAPEFQKEPEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGT 2484

Query: 535  PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              L +       +L I   K  D+  Y   A++ AG
Sbjct: 2485 RRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAG 2520



 Score =  128 bits (309), Expect = 1e-28
 Identities = 112/462 (24%), Positives = 189/462 (40%), Gaps = 39/462 (8%)

Query: 4371 EVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKP-PIFTKKMQP-CRVFEHEQA 4428
            +VV +      +T  E   +E K   +   VE  V  + P PI  K +     V E +  
Sbjct: 2068 KVVAENVAGEAVTDAEVI-VEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSV 2126

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
            R E    G P   + WY++++ ++        T   +  LII+   ++D A +  V  N 
Sbjct: 2127 RLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNI 2186

Query: 4489 GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
             G+      L+VEE       GI  P      ++     G +VR D +V G     V W 
Sbjct: 2187 AGSVDVKTELIVEE-------GISLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPVVEWF 2239

Query: 4549 KNGKKVQPDIRNKILEE-----DGTYTLLILEAYPQDSGKYECVAINSAGE--------- 4594
            KN + +    +  I+++        ++L+I    P+D   Y  VA+N AG+         
Sbjct: 2240 KNDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLV 2299

Query: 4595 ---------ARCDAECVVSLPATKDKPK-PQTKAANAP---PEIIEPLKDKIVAEGQAIE 4641
                     A+ DA   +  P  +  P+ P+ +AA+     P  IE +K+  V EG+   
Sbjct: 2300 NSKPEQEAPAQADAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEAR 2359

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPS-KYFQMSRTADE-YTLRISEAFPEDEGDYKCVAYN 4699
            F   + G P P++ WY+G++LI    ++  +    +E +TL I      D G Y C+A N
Sbjct: 2360 FDVHVDGVPEPSIDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAAN 2419

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
                +T  A L V   + A             V  G        +T K  P ++W ++  
Sbjct: 2420 DVDEITCEAVLTVKPKEIAPEFQKEPEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDK 2479

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +  T   ++  + +   L I     +D+G +T  A + AG+
Sbjct: 2480 PVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAGR 2521



 Score =  126 bits (305), Expect = 3e-28
 Identities = 119/504 (23%), Positives = 207/504 (41%), Gaps = 52/504 (10%)

Query: 252  ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311
            I  E++       PP+     ++ +L+EG+     V+  G     + WFK+ + L+   +
Sbjct: 1982 IVEELEAVESEAEPPRFVTPLKDQELEEGSTVDMLVETDGTSPIHIKWFKDNKELVPDER 2041

Query: 312  HEIITTHNHTTLRVRN-TQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
            H      N  T+ +   T + ++ +Y ++AEN  G  VT   + VE    + V       
Sbjct: 2042 HTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTP----- 2096

Query: 371  ITDTQQRETEERIEISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFIND 429
                     EE ++ +  A  P  +K   D  DV EG   R +C ++G P  +V W+ +D
Sbjct: 2097 --------VEEVVDAAVPA--PIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDD 2146

Query: 430  RQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
              + +D   +I+ +  G+ H L+I +  L D     CV  N +G  +   +  +I +E +
Sbjct: 2147 YLLEED--ERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG--SVDVKTELIVEEGI 2202

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-----HTDG 543
              P   E        EG+ V  + R  G P P + W K+   +  + +  I       D 
Sbjct: 2203 SLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDK 2262

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXX 603
               +L I      D A Y   A N AG  +++ +L              L   +P +   
Sbjct: 2263 ELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKL--------------LVNSKPEQ--E 2306

Query: 604  XXXXXXXXXXYLRHVERARPYIPPGEEDRVYP---PPQFIVPLKSVTAMEGGKIHFETRI 660
                       L  +    P +P  EE+   P    P FI  +K++  MEG +  F+  +
Sbjct: 2307 APAQADAATPILEPLVETIPEVP--EEEAASPETKAPVFIETMKNIEVMEGEEARFDVHV 2364

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSI--FRFGYISLDMLSLNIQDSGEYTCRAVSATG 718
            + V +P+  I+W +  + I    RF  I   +    +L + +  + D+G+YTC A +   
Sbjct: 2365 DGVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVD 2422

Query: 719  VAETKAVLHVTPRATIERTSQHPE 742
                +AVL V P+       + PE
Sbjct: 2423 EITCEAVLTVKPKEIAPEFQKEPE 2446



 Score =  126 bits (304), Expect = 4e-28
 Identities = 130/506 (25%), Positives = 211/506 (41%), Gaps = 59/506 (11%)

Query: 87   GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146
            G+ +   ++ G P P   WT+     ++       +      ++L++K   P D+G Y C
Sbjct: 789  GDVRLSVRVAGKPEPNFKWTKDDED-IDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKC 847

Query: 147  TARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHV---SETVEHKAYGTQGYTTEQSRQ 203
            TA N+ G    +  +  EG                V   S T+E ++ G +       + 
Sbjct: 848  TATNKGGTVTRTFQVNMEGIDTGPQIQEYSKEIEVVEGSSVTIECQSSGAEDARITWYKD 907

Query: 204  TQ--------KVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESI-TKRYVGESDVQIST 254
                      + A+ NG       D  +D        E  +R  I T R V    V ++T
Sbjct: 908  DVPLGDSPRFETAFDNGLCSLRIHDIVIDD-------EAEYRCDIATDRGV----VSMTT 956

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
            E+      V  P I Q  ++ +++E   A+F V++ G+P+P V WFK+G++L +  +  I
Sbjct: 957  ELIVEEA-VLMPVIIQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLGRFMI 1015

Query: 315  ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDT 374
                      + +    D   Y+L+ E+    ++       E      V +      T T
Sbjct: 1016 ----------IDDVDDQDKELYSLVIED----VIPEDAGEYECVA---VNEAGKATSTAT 1058

Query: 375  QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-- 432
             Q  T+    ISE    P  V   +  D+T          V+G P  EV W+ +DR++  
Sbjct: 1059 LQVLTK----ISELDKTP--VHTVEGSDIT------MKVAVSGTPRTEVEWYKDDRKLSN 1106

Query: 433  RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPK 492
            R  Y  K  V++   + L IT+ + SD+G   CV +N SG       + ++EK +  AP+
Sbjct: 1107 RKPYVIKTTVDD---YELTITSASPSDAGTYKCVTKNDSGTFTQMFDITIVEKPEGAAPE 1163

Query: 493  FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552
            F++    L V E +PV L     GTP P+ITW K G  +  +  +    DG    L+I  
Sbjct: 1164 FIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITTVFDGETCVLNITV 1223

Query: 553  AKASDAAWYQCTAQNVAGSTATRARL 578
            +   D   Y+C A N  G  AT A L
Sbjct: 1224 SCLDDEGEYKCLAMNDFGKAATVAEL 1249



 Score =  126 bits (303), Expect = 6e-28
 Identities = 106/451 (23%), Positives = 196/451 (43%), Gaps = 34/451 (7%)

Query: 4381 KITSTETTEIEHKAQ-TQERVVEGPVKPSKPPIFTKK--MQPCRVFEHEQARFEVEFDGE 4437
            K T T + +IE K   T+E   + P K  + P F     ++  ++ +  + R  V+  G+
Sbjct: 630  KSTRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGK 689

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILI-IRQVFVEDSAVFAAVAENRGGTAKCSA 4496
            P P ++W +++  +K      I       +++ I+ V   DS V+     +  GT+  S 
Sbjct: 690  PFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSF 749

Query: 4497 NLVVEEKRRQGRGGI-----VPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549
            ++ +E +RR+ +  I     V P F    +     +T    VRL  +V G    +  W K
Sbjct: 750  DVTIEGERRKAKKLIEVDDTVAPHFVEDTSIAPFELTDSGDVRLSVRVAGKPEPNFKWTK 809

Query: 4550 NGKKVQPDIRNKILEE-DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            + + +         E  D   TL++    P D G Y+C A N  G      +        
Sbjct: 810  DDEDIDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQV------- 862

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
                    +  +  P+I E  K+  V EG ++   C+  G     + WYK D  +  S  
Sbjct: 863  ------NMEGIDTGPQIQEYSKEIEVVEGSSVTIECQSSGAEDARITWYKDDVPLGDSPR 916

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPL 4727
            F+ +      +LRI +   +DE +Y+C      G V++  +L V   ++A  +P  + PL
Sbjct: 917  FETAFDNGLCSLRIHDIVIDDEAEYRCDIATDRGVVSMTTELIV---EEAVLMPVIIQPL 973

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA-----VLLIGN 4782
            + + + E   A+F  ++    +P ++W ++G  + +   F +I + ++       L+I +
Sbjct: 974  KSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIED 1033

Query: 4783 TYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               ED G + C A   AG+  ++A L V +K
Sbjct: 1034 VIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score =  116 bits (278), Expect = 6e-25
 Identities = 84/335 (25%), Positives = 143/335 (42%), Gaps = 10/335 (2%)

Query: 4379 TRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438
            +R+  +T + ++    +  E V +  +K     + + +++P  V E    +  V+  G+P
Sbjct: 40   SRRCKTTASAKLACLQRIPEEV-DAMLKEEPTFLESDEIKPFEVTEEGDIKLTVQVTGKP 98

Query: 4439 LPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL 4498
             P ++W +++ P+       I        L+I++   +D   +     N  G  + + ++
Sbjct: 99   QPSVEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDV 158

Query: 4499 VVEEKRRQGRGGIVPPSFTLTAQNV--NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             V++ R+      V P F      V    T    VRL  KVTG    +V W K+GK V  
Sbjct: 159  SVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDK 218

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA--RCDAECVVSLPATKDKPKP 4614
                ++  ++  Y L I EA P DSG Y C   +  G++      +     PA K+  K 
Sbjct: 219  LPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESEGPAPKESEKR 278

Query: 4615 QTKAANAPPEIIEPL---KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671
            +       P+ +      + KI  EG+ +  + K+ GKP P V+W K DK +K      +
Sbjct: 279  KLLKGEERPKFVSDSTVEEFKITDEGE-LRLTVKVTGKPFPEVEWTKDDKDLKEDDRVII 337

Query: 4672 SRTADE-YTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            S   D    LRI +    D G YKC   +  G  T
Sbjct: 338  SEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTST 372



 Score =  116 bits (278), Expect = 6e-25
 Identities = 121/551 (21%), Positives = 216/551 (39%), Gaps = 33/551 (5%)

Query: 4281 LQELENEQVIKESRLRESTHQYAIPGDKVTSNTVA---KSMAQRYEDNLDQTEEVTEQRV 4337
            + E E+E +I +        +  IPG K     V    K +  +  + L     +  ++ 
Sbjct: 1554 VSEAEDEGIIPKVTPTPGKTEITIPGQKPKFGPVEVDIKGLKDKERERLTSEASIAGRKP 1613

Query: 4338 QKKVTQKPRIP-DPSESTVHGKEVHVAKQKQTQKEV-VGDKEITRKITSTETTEIEHKAQ 4395
               V      P +  + TV   E      K  +  V +GD+     +   +  ++   A+
Sbjct: 1614 FGAVDMSITAPGEDKKPTVTEAEFTPVAFKPVEISVPIGDEAPFISLKGAKKPDLPVLAK 1673

Query: 4396 TQERVVEGPVKPSKP-PIFTKKMQP-CRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
              E ++     P++  P   K +     V E + AR E    G P   + WY++++ ++ 
Sbjct: 1674 PLEVIMPVSFTPAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEE 1733

Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513
                   T   +  LII+   ++D A +  V  N  G+      L+VEE       GI  
Sbjct: 1734 DERVSYETDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEE-------GISL 1786

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGK-----KVQPDIRNKILEEDGT 4568
            P      ++     G++VR D +V G KP    WL   +     K+   I + + ++D  
Sbjct: 1787 PVIKEGLKDTEANEGEIVRFDIRVAG-KPEP--WLNGSRMTSLWKILFIIIDDVDDKDKE 1843

Query: 4569 YTLLILE-AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
               L++E   P D   Y  VA+N AG+     + +V       +PK +     A P I +
Sbjct: 1844 LFSLVIEGCAPDDDAVYSVVAMNEAGKDTSKGKLLV-----HSRPKQEQPTEPAGPRITK 1898

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
             L D  V E   +    + V +   +V W K    +       +       TL IS++  
Sbjct: 1899 ELVDAEVEETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDV 1958

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQ----PDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
            +DEG Y C   N  G  + +A++ V +      +A+    +TPL+D  + EG       +
Sbjct: 1959 DDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPLKDQELEEGSTVDMLVE 2018

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN-TYEEDTGTFTCRATTAAGQV 4802
                    I+W ++   +          +GN   + I   T E++   +   A   AG+ 
Sbjct: 2019 TDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEA 2078

Query: 4803 ETSAKLVVKSK 4813
             T A+++V+ K
Sbjct: 2079 VTDAEVIVEVK 2089



 Score =  115 bits (276), Expect = 1e-24
 Identities = 87/300 (29%), Positives = 134/300 (44%), Gaps = 31/300 (10%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            EG+D   +V +SG PR  V W+K+ ++L N   + I TT +   L + +   SD+G Y  
Sbjct: 1077 EGSDITMKVAVSGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYK- 1135

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
                   C+  +     +S T + + D     IT  ++ E            AP+F+K  
Sbjct: 1136 -------CVTKN-----DSGTFTQMFD-----ITIVEKPE----------GAAPEFIKPL 1168

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +  +V E +  R +C VTG P P++TW      +++D +    V +     L IT   L 
Sbjct: 1169 KVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKED-DRITTVFDGETCVLNITVSCLD 1227

Query: 459  DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
            D G   C+A N  G+ A    L V   E +V PKF+E      +  GE V    +  G+P
Sbjct: 1228 DEGEYKCLAMNDFGKAATVAELLV--NEALVKPKFIETTHDTEIITGESVWFRVKYEGSP 1285

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            TP + W  +   +       I+T+   STL I   K  D   Y+C   N AG   T ++L
Sbjct: 1286 TPDVDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKL 1345



 Score =  113 bits (271), Expect = 4e-24
 Identities = 119/516 (23%), Positives = 211/516 (40%), Gaps = 53/516 (10%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM--RYNEQTGDV 129
            P+  Q  K+    +   A+F+ ++RG+P P+V W +    L +  ++ +    ++Q  ++
Sbjct: 967  PVIIQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKEL 1026

Query: 130  -SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH 188
             SL+I+ + P D GEY C            V +   G                + +T  H
Sbjct: 1027 YSLVIEDVIPEDAGEYEC------------VAVNEAGKATSTATLQVLTKISELDKTPVH 1074

Query: 189  KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES 248
                    T E S  T KVA  +GT  +  + +K D       R++S R    K YV ++
Sbjct: 1075 --------TVEGSDITMKVA-VSGTPRTEVEWYKDD-------RKLSNR----KPYVIKT 1114

Query: 249  DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQ-FQVQLSGNPRPRVTWFKNGQRLI 307
             V    + + ++   SP         +K   G   Q F + +   P      F    +++
Sbjct: 1115 TVD---DYELTITSASPSDAGTYKCVTKNDSGTFTQMFDITIVEKPEGAAPEFIKPLKVL 1171

Query: 308  NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ- 366
               + + +      T      Q +      ++ E+     V  G   V + T S + D+ 
Sbjct: 1172 EVFETQPVRLECSVT-GTPEPQITWLKGGDVVKEDDRITTVFDGETCVLNITVSCLDDEG 1230

Query: 367  --RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT 424
              +   + D  +  T   + ++E  + P+F++   D ++  G+   F  +  G P P+V 
Sbjct: 1231 EYKCLAMNDFGKAATVAELLVNEALVKPKFIETTHDTEIITGESVWFRVKYEGSPTPDVD 1290

Query: 425  WFINDRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            W+  D  + D    + L+N E     L+I +V   D G   C+  N +GE     +L VI
Sbjct: 1291 WYHEDTLVSD--TGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVI 1348

Query: 484  EKEQVVA-----PKFVERFST--LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536
            EK++ +      P+F        L + +G  + L  +  G P P I W KD  P+ P+ +
Sbjct: 1349 EKKKPITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQK 1408

Query: 537  LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            +R+       +L I  A   D A Y C A N +G+T
Sbjct: 1409 IRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTT 1444



 Score =  110 bits (264), Expect = 3e-23
 Identities = 132/550 (24%), Positives = 224/550 (40%), Gaps = 58/550 (10%)

Query: 46  RQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSW 105
           + + T+V+     + + A    EP+    ++I K     + G+ K   ++ G P P V W
Sbjct: 420 KPVETKVDKPRQIEEVDAMLKEEPTFLESDEI-KPFEVTEEGDIKMTAQVTGKPQPSVEW 478

Query: 106 TRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
            +   P+      ++   E+ G  SL+IK+    DEG YT    N+ G    +  +  + 
Sbjct: 479 FKDDVPVSPDEHITI--TEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDD 536

Query: 166 XXXXXXXXXXXXXYRHVSETVEHKAY--GTQGYTTEQSRQTQ-KVAYT-NGTDHSSTDDF 221
                        +      V  ++   G    T + + + + +V +T +G       + 
Sbjct: 537 TRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKLPNV 596

Query: 222 KVDTFEYRLL---REVSFRESITKRYVGESDVQISTE---ID-RSLGPVSPPKIAQKPRN 274
           ++D  E R +   RE S  +S + R    SDV  ST    +D  S GP +     +KPR 
Sbjct: 597 ELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESKGPATKESEKKKPRK 656

Query: 275 S---------------KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
                           K+ +  + +  V+++G P P V W K+ + L   N+  II+  +
Sbjct: 657 GEERPKFVSDSTLEEFKITDEGELRLTVKVTGKPFPEVEWTKDDKDLKEDNR-VIISEQD 715

Query: 320 H--TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR 377
                LR+++    DSG Y         C VTS    V + T+S+          + ++R
Sbjct: 716 DGIVVLRIKDVGAHDSGVYK--------CKVTSD---VGTSTKSF------DVTIEGERR 758

Query: 378 ETEERIEISEKALAPQFVKVCQDR--DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
           + ++ IE+ +  +AP FV+       ++T+    R   RV G+P P   W  +D  I   
Sbjct: 759 KAKKLIEVDD-TVAPHFVEDTSIAPFELTDSGDVRLSVRVAGKPEPNFKWTKDDEDIDFR 817

Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETA--FQCRLNVIEKEQVVAPKF 493
            +            L++ + + SD G   C A NK G     FQ  +  I+      P+ 
Sbjct: 818 SSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQVNMEGID----TGPQI 873

Query: 494 VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
            E    + V EG  V +  ++ G    RITW KD VP+  +P      D G  +L I   
Sbjct: 874 QEYSKEIEVVEGSSVTIECQSSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDI 933

Query: 554 KASDAAWYQC 563
              D A Y+C
Sbjct: 934 VIDDEAEYRC 943



 Score =  108 bits (259), Expect = 1e-22
 Identities = 79/315 (25%), Positives = 139/315 (44%), Gaps = 25/315 (7%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            PK  +   ++++  G    F+V+  G+P P V W+     + ++ +  I T  + +TL +
Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTLII 1317

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
             + +  D G+Y  +  N  G  +T   L V          ++ + ITD      E    +
Sbjct: 1318 EDVKPIDKGNYKCIISNDAGEDMTVSKLTVI---------EKKKPITDVGT-PPEFSPHV 1367

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
             E  L     K+    D+T       + ++TG P PE+ WF +D+ ++   + KI V+  
Sbjct: 1368 GEGPL-----KISDGGDLT------LEVKITGEPKPEIQWFKDDKPVKP--SQKIRVDYR 1414

Query: 446  GN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVR 503
             + H+L I   +  D+   TC A NKSG T     +++     +  APK+VE   +  + 
Sbjct: 1415 DDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGEAPKYVEPLKSDEIV 1474

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            E     +N +  GTP P + W K+  P+  +  + I  +  +STL I +    D   Y+ 
Sbjct: 1475 EDSSFTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKI 1534

Query: 564  TAQNVAGSTATRARL 578
               N  G   + A L
Sbjct: 1535 VLSNPFGKAVSEAEL 1549



 Score =  101 bits (241), Expect = 2e-20
 Identities = 77/305 (25%), Positives = 127/305 (41%), Gaps = 20/305 (6%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            VT    +++  +VTG     V W K+   V PD    I EEDGTY+L+I E   +D G Y
Sbjct: 456  VTEEGDIKMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTY 515

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
                 N AG  R   +  V     K  PK   K          P +     EG  +  + 
Sbjct: 516  TVEVSNEAGLGRRTFDVSVD-DTRKTIPKDAVKPKFIEDGSFVPFQS--TDEGD-VRLTV 571

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR- 4703
            K+ GKP P V W K  K +      ++    D Y L I EA P+D G Y+C   +  G+ 
Sbjct: 572  KVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKS 631

Query: 4704 -----VTVAAKLKVT------QPDQADNLPAL---TPLRDIVVYEGQPAQFKTQITSKIK 4749
                 V + +K   T      +P + +  P     + L +  + +    +   ++T K  
Sbjct: 632  TRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGKPF 691

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLL-IGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P ++W ++   + E     +  + +  V+L I +    D+G + C+ T+  G    S  +
Sbjct: 692  PEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFDV 751

Query: 4809 VVKSK 4813
             ++ +
Sbjct: 752  TIEGE 756



 Score = 99.5 bits (237), Expect = 6e-20
 Identities = 120/540 (22%), Positives = 200/540 (37%), Gaps = 55/540 (10%)

Query: 66   PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            P E +P I + +       +G +A+ E  + G P   V W +    L E  + S  Y   
Sbjct: 1685 PAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEEDERVS--YETD 1742

Query: 126  TGDVSLLIKQIGPGDEGEYTCTARNQYGEA-ICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184
                +L+I+     DE EY C   N  G   + +  I  EG               +  E
Sbjct: 1743 GDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISLPVIKEGLKDTEANEGE 1802

Query: 185  TVEH--KAYGTQGYTTEQSRQTQ--KVAYT--NGTDHSSTDDFKV-----DTFEYRLLRE 233
             V    +  G        SR T   K+ +   +  D    + F +        +  +   
Sbjct: 1803 IVRFDIRVAGKPEPWLNGSRMTSLWKILFIIIDDVDDKDKELFSLVIEGCAPDDDAVYSV 1862

Query: 234  VSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293
            V+  E+      G+  V    + ++   P  P +I ++  +++++E        +     
Sbjct: 1863 VAMNEAGKDTSKGKLLVHSRPKQEQPTEPAGP-RITKELVDAEVEETTPVTLVAEFVSEG 1921

Query: 294  RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
               VTW K+  R++  N+  I T    +TL +  +   D G YT    N  G   TS  +
Sbjct: 1922 ETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEV 1981

Query: 354  AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDC 413
             V                        EE   +  +A  P+FV   +D+++ EG       
Sbjct: 1982 IV------------------------EELEAVESEAEPPRFVTPLKDQELEEGSTVDMLV 2017

Query: 414  RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV-TCVARNKSG 472
               G     + WF +++++  D  H     +   H + I+ VTL D  +    VA N +G
Sbjct: 2018 ETDGTSPIHIKWFKDNKELVPDERHTF-TKDGNKHTMTISPVTLEDEAMYYKVVAENVAG 2076

Query: 473  ETAFQCRLNVIEKEQ-------------VVAPKFVERFST-LNVREGEPVVLNARAVGTP 518
            E      + V  KE              V AP  ++  +  ++V EG+ V L     G P
Sbjct: 2077 EAVTDAEVIVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRLECVISGGP 2136

Query: 519  TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              ++ W KD   +  +  +   TDG   TL I  A+  D A Y+C   N+AGS   +  L
Sbjct: 2137 DAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL 2196



 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 81/307 (26%), Positives = 131/307 (42%), Gaps = 27/307 (8%)

Query: 282 DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAE 341
           D +  V+++G P P VTW K+G+ +      E+    +   L +R     DSG Y     
Sbjct: 566 DVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLT 625

Query: 342 NPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDR 401
           +  G    +  + +ES   +  + ++ +       R+ EER +    +   +F      +
Sbjct: 626 SDVGKSTRTFSVDIESKGPATKESEKKK------PRKGEERPKFVSDSTLEEF------K 673

Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
              EG++ R   +VTG+P+PEV W  +D+ +++D    I   + G   L I +V   DSG
Sbjct: 674 ITDEGEL-RLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSG 732

Query: 462 VVTCVARNKSGET--AFQCRL--------NVIEKEQVVAPKFVE--RFSTLNVREGEPVV 509
           V  C   +  G +  +F   +         +IE +  VAP FVE    +   + +   V 
Sbjct: 733 VYKCKVTSDVGTSTKSFDVTIEGERRKAKKLIEVDDTVAPHFVEDTSIAPFELTDSGDVR 792

Query: 510 LNARAVGTPTPRITWQKDGVPI-IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
           L+ R  G P P   W KD   I   + +          TL +     SD   Y+CTA N 
Sbjct: 793 LSVRVAGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATN- 851

Query: 569 AGSTATR 575
            G T TR
Sbjct: 852 KGGTVTR 858



 Score = 98.3 bits (234), Expect = 1e-19
 Identities = 145/697 (20%), Positives = 276/697 (39%), Gaps = 102/697 (14%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFE--- 1598
            I   T+ + G   ++V  +     RT  V    T+  I   ++K   I++G    F+   
Sbjct: 130  IKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTD 189

Query: 1599 ----RRLIPVSDATL-KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCR 1653
                R  + V+     +V W  + KP+         +      L I    P+DSG+Y C 
Sbjct: 190  EGDVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCT 249

Query: 1654 AINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVF 1713
              + +G+          S ++  ++ + EG  P+ ++     K  +   + + ++ + V 
Sbjct: 250  LTSDVGK----------STRTFSVDIESEGPAPKESEKR---KLLKGEERPKFVSDSTV- 295

Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR-LTTMHDFGYVALNM 1772
                ++ ++ +        ++   G P   VEW ++   ++  +R + +  D G V L +
Sbjct: 296  ----EEFKITDEGELRLTVKV--TGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRI 349

Query: 1773 KYVNPEDSGTYTCRAINELGEAVTSSTLFVQS---KASLQLESQHESALQK--------- 1820
            K V   DSG Y C+  +++G +  S  + ++    KA   +E      L+K         
Sbjct: 350  KDVGAHDSGVYKCQVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPV 409

Query: 1821 ---------IQQLEDSSRYQRR-EDVEVAVNQAPRFITQLN-GPTKLSEGQSAHYECRIE 1869
                     ++ +E      R+ E+V+  + + P F+      P +++E        ++ 
Sbjct: 410  PEEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQVT 469

Query: 1870 PYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929
              P P+  VEW+ +   +        + + G  +L I     +D G YT +  N  G   
Sbjct: 470  GKPQPS--VEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGR 527

Query: 1930 SSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEV 1989
             +  ++V      I                 D+   + ++D SFV        P ++ + 
Sbjct: 528  RTFDVSVDDTRKTI---------------PKDAVKPKFIEDGSFV--------PFQSTD- 563

Query: 1990 TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGT 2049
             EG    +  T+     P   V W  +G+PV +    +  +      L I  A  +D+G+
Sbjct: 564  -EGD---VRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGS 619

Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRP 2109
            Y C  T+ VG++  T SV +++K                +E EK ++P+  EE     RP
Sbjct: 620  YRCTLTSDVGKSTRTFSVDIESKG------------PATKESEK-KKPRKGEE-----RP 661

Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH-DFGYVA 2168
             F++  T LE  K  D       V+    P   ++W  + + ++  +R   +  D G V 
Sbjct: 662  KFVSDST-LEEFKITDEGELRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVV 720

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR 2205
            L I    A DSG Y CK T+ +G +  +  + + G R
Sbjct: 721  LRIKDVGAHDSGVYKCKVTSDVGTSTKSFDVTIEGER 757



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 166/760 (21%), Positives = 294/760 (38%), Gaps = 121/760 (15%)

Query: 276  KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSG 334
            ++ E  D +  VQ++G P+P V W K+    ++ ++H  IT  + T +L ++   K D G
Sbjct: 81   EVTEEGDIKLTVQVTGKPQPSVEWLKDDVP-VSPDEHITITEEDDTYSLVIKEPTKKDEG 139

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQF 394
             YT+   N  G                    +R+  ++    R+T     I + A+ P+F
Sbjct: 140  TYTVEVSNEAGL------------------GRRTFDVSVDDTRKT-----IPKDAVKPKF 176

Query: 395  VK---VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            ++       +   EG + R   +VTG+P PEVTW  + + + D   +  L ++   + L 
Sbjct: 177  IEDGSFVPFQSTDEGDV-RLTVKVTGKPEPEVTWTKDGKPV-DKLPNVELDHQEDRYILT 234

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNV---------IEKEQVV----APKFVERFS 498
            I   +  DSG   C   +  G++     +++          EK +++     PKFV   +
Sbjct: 235  IREASPDDSGSYRCTLTSDVGKSTRTFSVDIESEGPAPKESEKRKLLKGEERPKFVSDST 294

Query: 499  TLNVR---EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI-HTDGGASTLDIPRAK 554
                +   EGE + L  +  G P P + W KD   +  +  + I   D G   L I    
Sbjct: 295  VEEFKITDEGE-LRLTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVG 353

Query: 555  ASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRL-------HLPRPTK-VXXXXX 606
            A D+  Y+C    V+    T  + +           K+L       HL +  K V     
Sbjct: 354  AHDSGVYKC---QVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVP 410

Query: 607  XXXXXXXYLRHVERA--RPYIPPGEEDRVYPPPQFIV--PLKSVTAMEGGKIHFETRIEP 662
                    ++ VE    +P      +  +   P F+    +K     E G I    ++  
Sbjct: 411  EEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQV-- 468

Query: 663  VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET 722
             G P   +EW K+   +      T     G  SL +     +D G YT    +  G+   
Sbjct: 469  TGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLG-- 526

Query: 723  KAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGEL 782
                    R T +              ++D  K   +++++ +  +   F+ P Q   E 
Sbjct: 527  --------RRTFD------------VSVDDTRKTIPKDAVKPKFIEDGSFV-PFQSTDE- 564

Query: 783  QEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGS 842
                +     ++T   +P   V W KDG+P+     +          L I     +D+GS
Sbjct: 565  ---GDVRLTVKVTGKPEP--EVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGS 619

Query: 843  YTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXV 902
            Y     + +G++  T S+ + ++   T +    + R+  E+                  V
Sbjct: 620  YRCTLTSDVGKSTRTFSVDIESKGPATKESEKKKPRKGEERP---------------KFV 664

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTF 961
             +ST + EFK  I D+              ++  G     VEW KD + ++  +R I + 
Sbjct: 665  SDSTLE-EFK--ITDE--------GELRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISE 713

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             + G V L IK V  HD+G Y C+  + +G +T S ++TI
Sbjct: 714  QDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFDVTI 753



 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 77/306 (25%), Positives = 128/306 (41%), Gaps = 22/306 (7%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            VT    ++L  +VTG     V WLK+   V PD    I EED TY+L+I E   +D G Y
Sbjct: 82   VTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTY 141

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
                 N AG  R   +  V     K  PK   K          P +     EG  +  + 
Sbjct: 142  TVEVSNEAGLGRRTFDVSVD-DTRKTIPKDAVKPKFIEDGSFVPFQS--TDEGD-VRLTV 197

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            K+ GKP P V W K  K +      ++    D Y L I EA P+D G Y+C   +  G+ 
Sbjct: 198  KVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKS 257

Query: 4705 T---------------VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749
            T                + K K+ + ++     + + + +  + +    +   ++T K  
Sbjct: 258  TRTFSVDIESEGPAPKESEKRKLLKGEERPKFVSDSTVEEFKITDEGELRLTVKVTGKPF 317

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNN--AVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            P ++W ++   + E  D  +I E ++   VL I +    D+G + C+ ++  G    S  
Sbjct: 318  PEVEWTKDDKDLKE-DDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTSTKSFD 376

Query: 4808 LVVKSK 4813
            + ++ +
Sbjct: 377  VTIEGE 382



 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 63/197 (31%), Positives = 92/197 (46%), Gaps = 19/197 (9%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT----Y 4569
            P F  T +N+ V  G+  R D  V G     + W + G+++ PD   + +  D      +
Sbjct: 2341 PVFIETMKNIEVMEGEEARFDVHVDGVPEPSIDWYR-GEELIPD-EGRFVHIDAVKEEIF 2398

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            TL+I      D+GKY C+A N   E  C+A   V       KPK       AP    EP 
Sbjct: 2399 TLVIENTKLGDTGKYTCIAANDVDEITCEAVLTV-------KPKEI-----APEFQKEPE 2446

Query: 4630 KDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            K    V  G  +     + GKP P V+W+K DK +K ++  ++    DE++L+I    P+
Sbjct: 2447 KSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPD 2506

Query: 4689 DEGDYKCVAYNSAGRVT 4705
            D G Y  VA + AGR T
Sbjct: 2507 DSGKYTVVAESPAGRDT 2523



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 184/918 (20%), Positives = 349/918 (38%), Gaps = 156/918 (16%)

Query: 1704 DEVITQAPVFTMPMKDIRVAE-NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM 1762
            D ++ + P F +   +I+  E  +    +  +   G P+  VEWL++ VP+     +T  
Sbjct: 62   DAMLKEEPTF-LESDEIKPFEVTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHITIT 120

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQ 1822
             +    +L +K    +D GTY               T+ V ++A L   +   S      
Sbjct: 121  EEDDTYSLVIKEPTKKDEGTY---------------TVEVSNEAGLGRRTFDVS------ 159

Query: 1823 QLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF 1882
             ++D+ +   ++ V+    +   F+     P + ++        ++   P+P   V W  
Sbjct: 160  -VDDTRKTIPKDAVKPKFIEDGSFV-----PFQSTDEGDVRLTVKVTGKPEPE--VTWTK 211

Query: 1883 NGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +GK +         +      L I     +DSG Y C   +++G++  +  ++++S+   
Sbjct: 212  DGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESEGPA 271

Query: 1943 IRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLT 2002
             ++S      EK + L+ + R K       FV +       ++  ++T+   + L   +T
Sbjct: 272  PKES------EKRKLLKGEERPK-------FVSDST-----VEEFKITDEGELRLTVKVT 313

Query: 2003 PVNDPTMRVEWYCNGRPVQQGHR-FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEA 2061
                P   VEW  + + +++  R   +  D G V L I    A D+G Y C+ ++ VG +
Sbjct: 314  --GKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTS 371

Query: 2062 VTTSSVKVD-----AKSGLYLDTLD--EQRLKKIQE--------------LE-KYERPKP 2099
              +  V ++     AK  + +D  +  E+R+K ++E              +E K ++P+ 
Sbjct: 372  TKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVPEEQVMPTKVKPVETKVDKPRQ 431

Query: 2100 IEEEQP--GQRPVFLTA--LTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            IEE      + P FL +  +   E  +EGD    +   +    P  +++WF +   +   
Sbjct: 432  IEEVDAMLKEEPTFLESDEIKPFEVTEEGD---IKMTAQVTGKPQPSVEWFKDDVPVSPD 488

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN 2215
                 T + G  +L I     +D GTY  + +N   EA                      
Sbjct: 489  EHITITEEDGTYSLVIKEPTKKDEGTYTVEVSN---EA---------------------- 523

Query: 2216 GLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKT-AHFECQVEPVHDPNL 2274
            GL + R  +     TR  + +  + P +F+ +  G+   F+          V+    P  
Sbjct: 524  GLGR-RTFDVSVDDTRKTIPKDAVKP-KFIED--GSFVPFQSTDEGDVRLTVKVTGKPEP 579

Query: 2275 RIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             + +  +GK +       +        L I+   P+D+G Y     + +G  T   S+ +
Sbjct: 580  EVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDI 639

Query: 2335 TAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTA 2394
             +KG    ES++                K+P   E    +RP F      ++  +     
Sbjct: 640  ESKGPATKESEK----------------KKPRKGE----ERPKFVSD-STLEEFKITDEG 678

Query: 2395 HFDCRLIPVGDPTLKVEWFRNEK-LIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRA 2453
                 +   G P  +VEW +++K L ED+  I    D G V + I  V   D GVY C+ 
Sbjct: 679  ELRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKV 738

Query: 2454 SNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQV 2513
            ++ +G               I+ E +  + + ++     PH                   
Sbjct: 739  TSDVG------TSTKSFDVTIEGERRKAKKLIEVDDTVAPH--------------FVEDT 778

Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM-GSRFRTTHDFGFVTLDINS 2572
               P EL +        RV   G P   F+W  +  ++    S++        +TL + S
Sbjct: 779  SIAPFELTDSGDVRLSVRV--AGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIVKS 836

Query: 2573 VVANDAGLYMCKAINRAG 2590
               +D G Y C A N+ G
Sbjct: 837  PSPSDQGTYKCTATNKGG 854



 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 66/247 (26%), Positives = 107/247 (43%), Gaps = 11/247 (4%)

Query: 1566 RTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSR 1625
            +T+++ E     P+    LK+ E  EG    F+ R+    +    VEW+ N++ L    +
Sbjct: 2193 KTELIVEEGISLPVIKEGLKDTEANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGK 2250

Query: 1626 F-----TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQ 1680
            F      +  +    +L I  C PED   Y+  A+N  G+  + G  +V+SK      +Q
Sbjct: 2251 FIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQ 2310

Query: 1681 HEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDP 1740
             + A P L  L +T             T+APVF   MK+I V E + A F+  +  V +P
Sbjct: 2311 ADAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEP 2370

Query: 1741 KLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPE--DSGTYTCRAINELGEAVTSS 1798
               ++W R    I    R   +         +   N +  D+G YTC A N++ E    +
Sbjct: 2371 S--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEA 2428

Query: 1799 TLFVQSK 1805
             L V+ K
Sbjct: 2429 VLTVKPK 2435



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 80/332 (24%), Positives = 145/332 (43%), Gaps = 41/332 (12%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            KP++I     + +++ G+ +    + E    PD  ++WY    ++    RF + ++    
Sbjct: 1257 KPKFI-ETTHDTEIITGESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRFLINTEEDTS 1313

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLE 3029
            TL + DV   D G Y C   N   +A    TV   SK  +IE+                 
Sbjct: 1314 TLIIEDVKPIDKGNYKCIISN---DAGEDMTV---SKLTVIEK----------------- 1350

Query: 3030 DSLRKEPGQQPDDDTGRPPEFTT-VFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG 3088
                    ++P  D G PPEF+  V +  + IS+G     E  +  TG+    I+WF + 
Sbjct: 1351 --------KKPITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDD 1400

Query: 3089 KTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE-CVDKSKGQ 3147
            K ++ S +IR  Y   +  L I+G    D+  Y+C+ATNK G    ++ ++      +G+
Sbjct: 1401 KPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGE 1460

Query: 3148 KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV 3207
             P++   +++ E ++D   + F   V     P  +++W+   +P+R   R+  + +    
Sbjct: 1461 APKYVEPLKSDEIVED---SSFTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDSS 1517

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
             L I  T   D G Y     N +G+  + A +
Sbjct: 1518 TLVITKTVPDDEGSYKIVLSNPFGKAVSEAEL 1549



 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 120/494 (24%), Positives = 198/494 (40%), Gaps = 74/494 (14%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P+F  P+K+ E+ EG  V +    T    P + ++W+ + + +    R   T D    
Sbjct: 1994 EPPRFVTPLKDQELEEGSTVDMLVE-TDGTSP-IHIKWFKDNKELVPDERHTFTKDGNKH 2051

Query: 2036 ALDILYAYAEDTGTYM-CKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094
             + I     ED   Y    A N  GEAVT + V V+              +K+  E+   
Sbjct: 2052 TMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVE--------------VKEAAEVTPV 2097

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            E  + ++   P   P+ +  L    ++ EGD    EC +     P   + W+ +   +  
Sbjct: 2098 E--EVVDAAVPA--PIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLLEE 2151

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL-KVAGHRNIILDTQH 2213
              R             I+Y    D  T + ++     EA   C +  +AG  ++      
Sbjct: 2152 DER-------------IMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDV------ 2192

Query: 2214 PNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPN 2273
                            T + VEE  IS P     L+ T    EG    F+ +V    +P 
Sbjct: 2193 ---------------KTELIVEEG-ISLPVIKEGLKDT-EANEGDVVRFDIRVAGKPEPV 2235

Query: 2274 LRIEFYHNGKALQSAARFHITFDFG-----YVSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
              +E++ N + L  + +F I  D         SL I+ C PED   YSV A+N  G  +S
Sbjct: 2236 --VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSS 2293

Query: 2329 AISMTVTAKGSIISESQRPEGLEKIREL-ESAEPFKRPEIPEPVTRQRPVFTQPLQNIDN 2387
               + V +K    + +Q       +  L E+       E   P T+  PVF + ++NI+ 
Sbjct: 2294 KGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVPEEEAASPETK-APVFIETMKNIE- 2351

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF--GYVSMTISHVRDED 2445
            + EG+ A FD  +  V +P+  ++W+R E+LI D  R            ++ I + +  D
Sbjct: 2352 VMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGD 2409

Query: 2446 EGVYMCRASNLLGE 2459
             G Y C A+N + E
Sbjct: 2410 TGKYTCIAANDVDE 2423



 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 86/337 (25%), Positives = 135/337 (40%), Gaps = 54/337 (16%)

Query: 259  SLGPVSPPKIAQKPRNSKLQ--EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
            S  P        KP N ++   EG  A+ +  +SG P   V W+K+   L    +    T
Sbjct: 1682 SFTPAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEEDERVSYET 1741

Query: 317  THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
              +  TL +++ +  D   Y         C+VT+   +V+  TE  V             
Sbjct: 1742 DGDQHTLIIQSAELDDEAEYK--------CVVTNIAGSVDVKTELIV------------- 1780

Query: 377  RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ----- 431
               EE I +      P   +  +D +  EG++ RFD RV G+P P   W    R      
Sbjct: 1781 ---EEGISL------PVIKEGLKDTEANEGEIVRFDIRVAGKPEP---WLNGSRMTSLWK 1828

Query: 432  ----IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK-- 485
                I DD + K    +    +L+I      D  V + VA N++G+   + +L V  +  
Sbjct: 1829 ILFIIIDDVDDK----DKELFSLVIEGCAPDDDAVYSVVAMNEAGKDTSKGKLLVHSRPK 1884

Query: 486  ----EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
                 +   P+  +      V E  PV L A  V      +TW KD   ++ +  + I T
Sbjct: 1885 QEQPTEPAGPRITKELVDAEVEETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKT 1944

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            D  +STL I ++   D   Y CT +N  G T+T A +
Sbjct: 1945 DETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEV 1981



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 205/965 (21%), Positives = 365/965 (37%), Gaps = 166/965 (17%)

Query: 1304 DITVMQAPQF--SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
            D  + + P F  S  +   E  E  ++ L   +Q  G     VEW  +  P+        
Sbjct: 62   DAMLKEEPTFLESDEIKPFEVTEEGDIKLT--VQVTGKPQPSVEWLKDDVPVSPDEHITI 119

Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
              E D  +L +     +D G YT + +N+ G    +  + V   +  I     P    K 
Sbjct: 120  TEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTI-----PKDAVKP 174

Query: 1422 QYLEDTS--RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVE 1479
            +++ED S   ++ TD  D  +T+K             + G       K EP      +V 
Sbjct: 175  KFIEDGSFVPFQSTDEGDVRLTVK-------------VTG-------KPEP------EVT 208

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W K+G+PV         H      L I +   +DSG Y C   + VG    +  +   S 
Sbjct: 209  WTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESE 268

Query: 1540 TDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599
                + ++    L+     E+R K+     V+E                  EG+     R
Sbjct: 269  GPAPKESEKRKLLKG----EERPKFVSDSTVEEFKIT-------------DEGEL----R 307

Query: 1600 RLIPVSDATL-KVEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPEDSGTYTCRAINA 1657
              + V+     +VEW  ++K LK   R      + G V L I      DSG Y C+  + 
Sbjct: 308  LTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSD 367

Query: 1658 LGEAVTSGIAIVH-----SKKSIYL-ESQH--------------EGALP-RLNQLED-TS 1695
            +G +  S    +      +KK I + E++H              E  +P ++  +E    
Sbjct: 368  VGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVPEEQVMPTKVKPVETKVD 427

Query: 1696 KYQRHSAQDEVITQAPVF--TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPI 1753
            K ++    D ++ + P F  +  +K   V E       A++   G P+  VEW ++ VP+
Sbjct: 428  KPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQV--TGKPQPSVEWFKDDVPV 485

Query: 1754 EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQ 1813
                 +T   + G  +L +K    +D GTY               T+ V ++A L   + 
Sbjct: 486  SPDEHITITEEDGTYSLVIKEPTKKDEGTY---------------TVEVSNEAGLGRRTF 530

Query: 1814 HESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPD 1873
              S       ++D+ +   ++ V+    +   F+     P + ++        ++   P+
Sbjct: 531  DVS-------VDDTRKTIPKDAVKPKFIEDGSFV-----PFQSTDEGDVRLTVKVTGKPE 578

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
            P   V W  +GK +         +      L I     +DSG Y C   +++G++  +  
Sbjct: 579  PE--VTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFS 636

Query: 1934 LNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGH 1993
            ++++SK    ++S      EK +  + + R K       FV +       ++  ++T+  
Sbjct: 637  VDIESKGPATKES------EKKKPRKGEERPK-------FVSDST-----LEEFKITDEG 678

Query: 1994 PVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR-FKTTYDFGYVALDILYAYAEDTGTYMC 2052
             + L   +T    P   VEW  + + +++ +R   +  D G V L I    A D+G Y C
Sbjct: 679  ELRLTVKVT--GKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKC 736

Query: 2053 KATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFL 2112
            K T+ VG +  +  V ++          + ++ KK+ E++    P  +E+          
Sbjct: 737  KVTSDVGTSTKSFDVTIEG---------ERRKAKKLIEVDDTVAPHFVED---------- 777

Query: 2113 TALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR-AGHRYRTTHDFGYVALDI 2171
            T++   E    GD       V     P     W  + + I     +Y        + L +
Sbjct: 778  TSIAPFELTDSGD---VRLSVRVAGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIV 834

Query: 2172 LYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE-AQGHST 2230
                  D GTY C ATNK G    T  + + G     +DT  P   E  +++E  +G S 
Sbjct: 835  KSPSPSDQGTYKCTATNKGGTVTRTFQVNMEG-----IDT-GPQIQEYSKEIEVVEGSSV 888

Query: 2231 RIEVE 2235
             IE +
Sbjct: 889  TIECQ 893



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 161/749 (21%), Positives = 284/749 (37%), Gaps = 110/749 (14%)

Query: 2797 VEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGS 2856
            V+ +  P  ++ W  + KP+      +  H      L I     +DSG Y C  T+  G 
Sbjct: 197  VKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGK 256

Query: 2857 ATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKPEWIIP 2916
            +T + S        +  +++ P       A +++E+ +L KG           +P+++  
Sbjct: 257  STRTFS--------VDIESEGP-------APKESEKRKLLKGEE---------RPKFVSD 292

Query: 2917 IAAEH-QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS-DFGFVTLDLV 2974
               E  ++ +   L L  +V  K  P+  +EW  + K L++  R  ++  D G V L + 
Sbjct: 293  STVEEFKITDEGELRLTVKVTGKPFPE--VEWTKDDKDLKEDDRVIISEQDDGIVVLRIK 350

Query: 2975 DVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEK-IQNLEDSLR 3033
            DV   DSG+Y C+  +  G +  S  V    +    ++      TE LEK I+++++ + 
Sbjct: 351  DVGAHDSGVYKCQVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVP 410

Query: 3034 KE--------PGQQPDDDTGRPPEFTTVFKDIVDISEG-QIAHYEA--------SLIPTG 3076
            +E        P +   D   +  E   + K+     E  +I  +E         +   TG
Sbjct: 411  EEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQVTG 470

Query: 3077 DQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISV 3136
                 +EWF +   +     I      G   L I      D GTY+   +N+ G    + 
Sbjct: 471  KPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTF 530

Query: 3137 KLECVDKSK-----GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
             +   D  K       KP+F     +    +         TV     P+ ++ W  +G+P
Sbjct: 531  DVSVDDTRKTIPKDAVKPKFIED-GSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKP 589

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251
            +     ++        +L I      DSG Y C   +  G+     +++   KG    ES
Sbjct: 590  VDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESKGPATKES 649

Query: 3252 LQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT-QIQDVTKLVEGQSAHFEARLVPVD 3310
                              +++ P     E PKF++    +  K+ +        ++    
Sbjct: 650  ------------------EKKKP-RKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGKP 690

Query: 3311 DPDLKVEWFYNGKKLPHGHR-YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTK 3369
             P+  VEW  + K L   +R   +  D GIV+L I      +SG Y+C  T+ +G  STK
Sbjct: 691  FPE--VEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVG-TSTK 747

Query: 3370 ANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRR--KDTSVEEEKGKAPVFTVPLS 3427
            +            D  +  G     +KL  ++D++     +DTS+      AP       
Sbjct: 748  S-----------FDVTI-EGERRKAKKLIEVDDTVAPHFVEDTSI------APF------ 783

Query: 3428 NIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF--CDFGFVILEISPT 3485
                L +  +     R+    +PN K  W  + + +   S   TF   D    ++  SP+
Sbjct: 784  ---ELTDSGDVRLSVRVAGKPEPNFK--WTKDDEDIDFRSSQYTFERVDDRLTLIVKSPS 838

Query: 3486 YPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
             P D G Y C A N  G    T  + ++G
Sbjct: 839  -PSDQGTYKCTATNKGGTVTRTFQVNMEG 866



 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 88/360 (24%), Positives = 152/360 (42%), Gaps = 42/360 (11%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G  PEF    K ++++ E Q    E S+  TG     I W   G  ++   RI TV+   
Sbjct: 1159 GAAPEFIKPLK-VLEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDRITTVFDGE 1215

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
              VL I  +   D G Y C A N +G+A    +L  V+++   KP+F     + E +  G
Sbjct: 1216 TCVLNITVSCLDDEGEYKCLAMNDFGKAATVAEL-LVNEAL-VKPKFIETTHDTE-IITG 1272

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +S  F         PD  ++WYH    +  + R    ++     L I   +  D G Y C
Sbjct: 1273 ESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYKC 1330

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
               N  GED T                     ++K+  +E      ++ P T    PP+F
Sbjct: 1331 IISNDAGEDMT---------------------VSKLTVIE------KKKPITDVGTPPEF 1363

Query: 3285 ITQI-QDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343
               + +   K+ +G     E ++    +P  +++WF + K +    + R  +   I  L 
Sbjct: 1364 SPHVGEGPLKISDGGDLTLEVKIT--GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLT 1421

Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDS 3403
            I+    +++ +Y C ATNK G  +   N+  ++   L+ + + P+ +E  L+  + +EDS
Sbjct: 1422 IVGASPDDTAKYTCKATNKSGTTTRNINVDISA---LMPEGEAPKYVE-PLKSDEIVEDS 1477



 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 138/607 (22%), Positives = 234/607 (38%), Gaps = 103/607 (16%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +V W  +  ++ + NR+    D     L I+    +D G+YT   RN  G          
Sbjct: 1924 SVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMG---------- 1973

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
                  DTS+    + E+   +E     EP           P FV PL +   + EG  +
Sbjct: 1974 ------DTSTSAEVIVEELEAVESE--AEP-----------PRFVTPLKDQE-LEEGSTV 2013

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY-TVRA 1254
             +   +E  G   + ++WF + + +    R     D     + I   T  D   Y  V A
Sbjct: 2014 DM--LVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVA 2071

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFS 1314
             N  G A T A        +++ + +    +  ++ + DAA            + AP   
Sbjct: 2072 ENVAGEAVTDA--------EVIVEVKEAAEVTPVEEVVDAA------------VPAPIII 2111

Query: 1315 RALHN-IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL 1373
            + L++ I+ +EG +V LEC +   G    +V W+ +   ++   R     + D   L + 
Sbjct: 2112 KPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQ 2169

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKT 1433
            S   +D   Y C  TN  G         V  K +LI+E      + K + L+DT    + 
Sbjct: 2170 SAELDDEAEYKCVVTNIAGS--------VDVKTELIVEEGISLPVIK-EGLKDTEA-NEG 2219

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            D++        RF  R       + G       K EPV      VEWFKN + +    +F
Sbjct: 2220 DVV--------RFDIR-------VAG-------KPEPV------VEWFKNDELLDDSGKF 2251

Query: 1494 RPIHDFGYVALDIIDLI-----AEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
              I D      ++  L+      ED  +Y+  A+N  G D    +L   S  +     Q 
Sbjct: 2252 IIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQA 2311

Query: 1549 EAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDAT 1608
            +A    ++ L +       +      T+AP+   ++KN+E+ EG+ A F+  +  V + +
Sbjct: 2312 DAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPS 2371

Query: 1609 LKVEWYHNNKPLKSGSRFTETN--NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGI 1666
              ++WY   + +    RF   +        L I +    D+G YTC A N + E     +
Sbjct: 2372 --IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAV 2429

Query: 1667 AIVHSKK 1673
              V  K+
Sbjct: 2430 LTVKPKE 2436



 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 204/918 (22%), Positives = 349/918 (38%), Gaps = 164/918 (17%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI- 1001
            VEWLKD  PV     IT        +L IK  T  D G YT    N  G    + ++++ 
Sbjct: 102  VEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVD 161

Query: 1002 VTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSA 1061
             T+K I      P    K +++ED S    ++ +E          G ++ T K+      
Sbjct: 162  DTRKTI------PKDAVKPKFIEDGSFVPFQSTDE----------GDVRLTVKVT----- 200

Query: 1062 HFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVAR 1121
                + EP+      V W  +GK +     ++  H      L I     +DSG Y     
Sbjct: 201  ---GKPEPE------VTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLT 251

Query: 1122 NAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQ 1181
            +  G++  + S+ +E+       S  R L +     E  KFV     +EE   +      
Sbjct: 252  SDVGKSTRTFSVDIESEGPAPKESEKRKLLKGE---ERPKFVSDS-TVEEFKIT------ 301

Query: 1182 PLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR-FKTYYDFGFVALDII 1240
                     EG+   L   ++  G P   VEW  + + +    R   +  D G V L I 
Sbjct: 302  --------DEGE---LRLTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIK 350

Query: 1241 HATSADTGEYTVRAVNHLGSAHTSAIV------RVIERSDIVTDTQN------------- 1281
               + D+G Y  +  + +G++  S  V      R  ++   V +T++             
Sbjct: 351  DVGAHDSGVYKCQVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVP 410

Query: 1282 -EQAI-EQIQLLEDAARRTKQVRE-DITVMQAPQF--SRALHNIETVEGTNVHLECRLQP 1336
             EQ +  +++ +E    + +Q+ E D  + + P F  S  +   E  E  ++ +    Q 
Sbjct: 411  EEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTA--QV 468

Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
             G     VEWF +  P+          E    +L +     +D G YT + +N+ G    
Sbjct: 469  TGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRR 528

Query: 1397 SCALRVIAKKDLILESQHPSGLEKIQYLEDTS--RYKKTDIIDESVTIKPRFVTRPKSIE 1454
            +  + V   +  I     P    K +++ED S   ++ TD  D  +T+K           
Sbjct: 529  TFDVSVDDTRKTI-----PKDAVKPKFIEDGSFVPFQSTDEGDVRLTVK----------- 572

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
              + G       K EP      +V W K+G+PV         H      L I +   +DS
Sbjct: 573  --VTG-------KPEP------EVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDS 617

Query: 1515 GIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVT 1574
            G Y C   + VG    +  +   S     + ++ +   +     E+R K+          
Sbjct: 618  GSYRCTLTSDVGKSTRTFSVDIESKGPATKESEKKKPRKG----EERPKF---------- 663

Query: 1575 TQAPICTTSLKNVEI-KEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSR-FTETNN 1631
                +  ++L+  +I  EG+     R  + V+     +VEW  ++K LK  +R      +
Sbjct: 664  ----VSDSTLEEFKITDEGEL----RLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQD 715

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691
             G V L I      DSG Y C+        VTS +        + +E +   A  +L ++
Sbjct: 716  DGIVVLRIKDVGAHDSGVYKCK--------VTSDVGTSTKSFDVTIEGERRKA-KKLIEV 766

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751
            +DT     H  +D  I  AP       D+R++   A          G P+   +W ++  
Sbjct: 767  DDT--VAPHFVEDTSI--APFELTDSGDVRLSVRVA----------GKPEPNFKWTKDDE 812

Query: 1752 PIE-ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
             I+  S++ T       + L +K  +P D GTY C A N+ G   T +  F  +   +  
Sbjct: 813  DIDFRSSQYTFERVDDRLTLIVKSPSPSDQGTYKCTATNKGG---TVTRTFQVNMEGIDT 869

Query: 1811 ESQHESALQKIQQLEDSS 1828
              Q +   ++I+ +E SS
Sbjct: 870  GPQIQEYSKEIEVVEGSS 887



 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 51/227 (22%), Positives = 100/227 (44%), Gaps = 9/227 (3%)

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEP--LKDKIVAEGQAIEFSCKIVGKPLPT 4653
            RC       L   +  P+         P  +E   +K   V E   I+ + ++ GKP P+
Sbjct: 42   RCKTTASAKLACLQRIPEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKLTVQVTGKPQPS 101

Query: 4654 VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT 4713
            V+W K D  + P ++  ++   D Y+L I E   +DEG Y     N AG       + V 
Sbjct: 102  VEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVD 161

Query: 4714 QPDQADNLPALTP--LRD--IVVYEGQ---PAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               +     A+ P  + D   V ++       +   ++T K +P + W ++G  + + P+
Sbjct: 162  DTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKLPN 221

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             ++ H+ +  +L I     +D+G++ C  T+  G+   +  + ++S+
Sbjct: 222  VELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESE 268



 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 112/446 (25%), Positives = 179/446 (40%), Gaps = 65/446 (14%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEAR--------LEPIGDSTLRVEWLKDGRPVEAS 955
            + T+K   K  +K +  I++G F  F++         ++  G     V W KDG+PV+  
Sbjct: 161  DDTRKTIPKDAVKPKF-IEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKL 219

Query: 956  SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPG 1015
              +          LTI+  +  D+G Y C   + +G++T + ++      DI +E   P 
Sbjct: 220  PNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSV------DIESEGPAPK 273

Query: 1016 GLEKIQYLEDASR---YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSD 1072
              EK + L+   R    S  T EE KIT +    G L+ T K+          +  P+  
Sbjct: 274  ESEKRKLLKGEERPKFVSDSTVEEFKITDE----GELRLTVKVT--------GKPFPE-- 319

Query: 1073 LTMTVEWYFNGKQITSANR-IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSA 1131
                VEW  + K +   +R I +  D G V L I  V A DSGVY     +  G +  S 
Sbjct: 320  ----VEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTSTKSF 375

Query: 1132 SMTVE-----TRSSIDTSSIHRGLYEKTRHIEE---------------SKFVEPMYQIEE 1171
             +T+E      +  I+       L ++ +H++E                  V+   QIEE
Sbjct: 376  DVTIEGERRKAKKLIEVDETEH-LEKRIKHVKEPVPEEQVMPTKVKPVETKVDKPRQIEE 434

Query: 1172 IS---KSKPVFVQPLS-NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            +    K +P F++     P  V+E  +I +  ++   G P   VEWF +   V+      
Sbjct: 435  VDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQV--TGKPQPSVEWFKDDVPVSPDEHIT 492

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAIE 1286
               + G  +L I   T  D G YTV   N  G    +  V V + R  I  D    + IE
Sbjct: 493  ITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIE 552

Query: 1287 QIQLLEDAARRTKQVREDITVMQAPQ 1312
                +   +     VR  + V   P+
Sbjct: 553  DGSFVPFQSTDEGDVRLTVKVTGKPE 578



 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 45/194 (23%), Positives = 92/194 (47%), Gaps = 7/194 (3%)

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
            + +K   V E   I+ + ++ GKP P+V+W+K D  + P ++  ++     Y+L I E  
Sbjct: 449  DEIKPFEVTEEGDIKMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPT 508

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP--LRD--IVVYEGQ---PAQ 4739
             +DEG Y     N AG       + V    +     A+ P  + D   V ++       +
Sbjct: 509  KKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVR 568

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
               ++T K +P + W ++G  + + P+ ++ H+ +  +L I     +D+G++ C  T+  
Sbjct: 569  LTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDV 628

Query: 4800 GQVETSAKLVVKSK 4813
            G+   +  + ++SK
Sbjct: 629  GKSTRTFSVDIESK 642



 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 101/455 (22%), Positives = 186/455 (40%), Gaps = 61/455 (13%)

Query: 65   RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
            +P EP+ P   +   +A   +        +        V+WT+    +V  N+ +++ +E
Sbjct: 1887 QPTEPAGPRITKELVDAEVEETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKTDE 1946

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184
             +   +L I +    DEG YTCT RN+ G+   S  +  E                 + +
Sbjct: 1947 TSS--TLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPLKD 2004

Query: 185  -------TVEH--KAYGTQGYTTEQSRQTQKV------AYT-NGTDHSSTDD---FKVDT 225
                   TV+   +  GT     +  +  +++       +T +G  H+ T      + + 
Sbjct: 2005 QELEEGSTVDMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEA 2064

Query: 226  FEYRLLREVSFRESIT--KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQ--EGA 281
              Y+++ E    E++T  +  V   +    T ++  +    P  I  KP N ++   EG 
Sbjct: 2065 MYYKVVAENVAGEAVTDAEVIVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGD 2124

Query: 282  DAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAE 341
              + +  +SG P  +V W+K+   L    +    T  +  TL +++ +  D   Y     
Sbjct: 2125 SVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYK---- 2180

Query: 342  NPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDR 401
                C+VT+   +V+  TE  V                EE I +      P   +  +D 
Sbjct: 2181 ----CVVTNIAGSVDVKTELIV----------------EEGISL------PVIKEGLKDT 2214

Query: 402  DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-----HALMITNVT 456
            +  EG + RFD RV G+P P V WF ND ++ DD    I++++  +      +L+I    
Sbjct: 2215 EANEGDVVRFDIRVAGKPEPVVEWFKND-ELLDDSGKFIIIDDVDDKDKELFSLVIEGCA 2273

Query: 457  LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
              D  V + VA N++G+ + + +L V  K +  AP
Sbjct: 2274 PEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAP 2308



 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 76/342 (22%), Positives = 135/342 (39%), Gaps = 14/342 (4%)

Query: 246  GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
            G +   I+ +I   +     PK  +  ++ ++ E +     V+ +G P P V WFK  + 
Sbjct: 1442 GTTTRNINVDISALMPEGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQWFKENKP 1501

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
            +   ++  II   + +TL +  T   D G Y ++  NP G  V+   L V + +E+  +D
Sbjct: 1502 VREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEA--ED 1559

Query: 366  QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR-PYPEVT 424
            +           +TE  I   +    P  V +   +D    ++T  +  + GR P+  V 
Sbjct: 1560 EGIIPKVTPTPGKTEITIPGQKPKFGPVEVDIKGLKDKERERLTS-EASIAGRKPFGAVD 1618

Query: 425  WFINDRQIRDDYNHKILVNESGNHALMITNVTL---SDSGVVTCVARNKSGETAFQCRLN 481
              I      +D    +   E    A     +++    ++  ++     K         L 
Sbjct: 1619 MSIT--APGEDKKPTVTEAEFTPVAFKPVEISVPIGDEAPFISLKGAKKPDLPVLAKPLE 1676

Query: 482  VIEKEQVV----APKFVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536
            VI          AP  ++  +  ++V EG+   L     G P   + W KD   +  +  
Sbjct: 1677 VIMPVSFTPAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEEDER 1736

Query: 537  LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +   TDG   TL I  A+  D A Y+C   N+AGS   +  L
Sbjct: 1737 VSYETDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL 1778



 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 101/484 (20%), Positives = 190/484 (39%), Gaps = 47/484 (9%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            ++E   P ++ P+  + +L EG  + +   VE      + I+W+ + K L    R   T 
Sbjct: 1990 ESEAEPPRFVTPLK-DQELEEGSTVDM--LVETDGTSPIHIKWFKDNKELVPDERHTFTK 2046

Query: 2965 DFGFVTLDLVDVYERDSGIY-TCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023
            D    T+ +  V   D  +Y    A N  GEA T + V                      
Sbjct: 2047 DGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEV---------------------- 2084

Query: 3024 KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIE 3083
             I  ++++    P ++  D     P       D +D+ EG     E  +I  G  + V+ 
Sbjct: 2085 -IVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRLEC-VISGGPDAQVL- 2141

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W+ +   +E   RI          L I   +  D   Y C  TN  G   + VK E + +
Sbjct: 2142 WYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGS--VDVKTELIVE 2199

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
                 P     +++ E   +G    F+  V     P+  +EW+ N + +  S +   + D
Sbjct: 2200 EGISLPVIKEGLKDTEA-NEGDVVRFDIRVA--GKPEPVVEWFKNDELLDDSGKFIIIDD 2256

Query: 3204 FG-----FVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLA 3258
                      L I      D   Y   A N+ G+D ++  +    K      + Q D+  
Sbjct: 2257 VDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPA-QADAAT 2315

Query: 3259 KIRE--LESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKV 3316
             I E  +E++    ++  ++P  + P FI  ++++ +++EG+ A F+  +  V +P   +
Sbjct: 2316 PILEPLVETIPEVPEEEAASPETKAPVFIETMKNI-EVMEGEEARFDVHVDGVPEPS--I 2372

Query: 3317 EWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEE--NSGEYECVATNKLGRDSTKANLKC 3374
            +W+   + +P   R+         I  ++    +  ++G+Y C+A N +   + +A L  
Sbjct: 2373 DWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTV 2432

Query: 3375 TSKE 3378
              KE
Sbjct: 2433 KPKE 2436



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 58/238 (24%), Positives = 108/238 (45%), Gaps = 14/238 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG---- 1766
            PV    +KD    E     F+ R+   G P+  VEW +N   ++ S +   + D      
Sbjct: 2205 PVIKEGLKDTEANEGDVVRFDIRV--AGKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDK 2262

Query: 1767 -YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
               +L ++   PED   Y+  A+NE G+  +   L V SK   +  +Q ++A   ++ L 
Sbjct: 2263 ELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLV 2322

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK 1885
            ++      E+      +AP FI  +    ++ EG+ A ++  ++  P+P+  ++WY   +
Sbjct: 2323 ETIPEVPEEEAASPETKAPVFIETMKN-IEVMEGEEARFDVHVDGVPEPS--IDWYRGEE 2379

Query: 1886 VLQSGHRY---RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            ++    R+       +  F  +   T  G D+G+YTC A N++ +      L V+ KE
Sbjct: 2380 LIPDEGRFVHIDAVKEEIFTLVIENTKLG-DTGKYTCIAANDVDEITCEAVLTVKPKE 2436



 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 89/383 (23%), Positives = 156/383 (40%), Gaps = 29/383 (7%)

Query: 2868 DKNIYFDTQHPQGKAGLEAVEQAEEAR---LAKGRRPSVP-DTEYPKPEWI-IPIAAEH- 2921
            D+ I +DT   Q    +++ E  +EA    +      SV   TE    E I +P+  E  
Sbjct: 2152 DERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISLPVIKEGL 2211

Query: 2922 ---QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVY- 2977
               +  EG V+  + +V  K +P   +EW+ N ++L+   +F +  D      +L  +  
Sbjct: 2212 KDTEANEGDVVRFDIRVAGKPEP--VVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVI 2269

Query: 2978 ----ERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLR 3033
                  D  +Y+  A N+ G+  +   +   SK       Q    T  LE +      + 
Sbjct: 2270 EGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVP 2329

Query: 3034 KEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA 3093
            +E    P+    + P F    K+I ++ EG+ A ++  +    + S  I+W+   + I  
Sbjct: 2330 EEEAASPET---KAPVFIETMKNI-EVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPD 2383

Query: 3094 SHRIRTVYAFG--MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF 3151
              R   + A    +  L I  TK  D+G Y+C A N     EI+ +     K K   P F
Sbjct: 2384 EGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVD--EITCEAVLTVKPKEIAPEF 2441

Query: 3152 TTHIQNIE-GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLD 3210
                +     +  G     + TV     P  K+EW+ + +P++ + R++  +      L 
Sbjct: 2442 QKEPEKSTFDVNTGDDVSLDLTVT--GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLK 2499

Query: 3211 IAYTQNHDSGEYVCRAYNKYGED 3233
            I   +  DSG+Y   A +  G D
Sbjct: 2500 IKGGKPDDSGKYTVVAESPAGRD 2522



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 62/231 (26%), Positives = 98/231 (42%), Gaps = 16/231 (6%)

Query: 3292 TKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG-----IVILDILY 3346
            T+  EG    F+ R+    +P   VEWF N + L    ++    D       +  L I  
Sbjct: 2214 TEANEGDVVRFDIRVAGKPEP--VVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEG 2271

Query: 3347 CYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVR 3406
            C  E+   Y  VA N+ G+DS+K  L   SK     + + P   +     L+ L +++  
Sbjct: 2272 CAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKP----EQEAPAQADAATPILEPLVETIPE 2327

Query: 3407 RKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAG 3466
              +      + KAPVF   + NIE + EGE A F+  +    +P+  ++WY   + +   
Sbjct: 2328 VPEEEAASPETKAPVFIETMKNIE-VMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDE 2384

Query: 3467 SRFRTF--CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
             RF            L I  T   D+G+Y C A N+  E    A + V+ K
Sbjct: 2385 GRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 164/744 (22%), Positives = 267/744 (35%), Gaps = 114/744 (15%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE- 3133
            TG     + W  +GK ++    +   +     +L I      DSG+Y C  T+  G++  
Sbjct: 200  TGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTR 259

Query: 3134 -ISVKLECVDKS----------KGQ-KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181
              SV +E    +          KG+ +P+F +    +E  K         TV     P  
Sbjct: 260  TFSVDIESEGPAPKESEKRKLLKGEERPKFVSD-STVEEFKITDEGELRLTVKVTGKPFP 318

Query: 3182 KIEWYHNGQPMRHSTR-IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
            ++EW  + + ++   R I +  D G VVL I     HDSG Y C+  +  G       + 
Sbjct: 319  EVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTSTKSFDVT 378

Query: 3241 CYG---KGGVYLESLQPDSLAK-IRELESLQGAQQQTPSTPSAEPPKFIT--QIQDVTKL 3294
              G   K    +E  + + L K I+ ++     +Q  P+       K     QI++V  +
Sbjct: 379  IEGERRKAKKLIEVDETEHLEKRIKHVKEPVPEEQVMPTKVKPVETKVDKPRQIEEVDAM 438

Query: 3295 VEGQSAHFEA-RLVP---VDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEE 3350
            ++ +    E+  + P    ++ D+K+     GK  P       F D   V  D      E
Sbjct: 439  LKEEPTFLESDEIKPFEVTEEGDIKMTAQVTGKPQPS---VEWFKDDVPVSPDEHITITE 495

Query: 3351 NSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDT 3410
              G Y  V      +D     ++ ++              E GL +         R  D 
Sbjct: 496  EDGTYSLVIKEPTKKDEGTYTVEVSN--------------EAGLGR---------RTFDV 532

Query: 3411 SVEEEKGKAPVFTVPLSNIEN-----LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKA 3465
            SV++ +   P   V    IE+      +  +       +  T  P  +V W  +GK +  
Sbjct: 533  SVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDK 592

Query: 3466 GSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLP 3525
                         IL I    P+DSG Y C   ++ G++  T S+         +ES+ P
Sbjct: 593  LPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVD--------IESKGP 644

Query: 3526 KGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRL-IPV 3584
               E    K    E     V   T E       EF  T              E RL + V
Sbjct: 645  ATKESEKKKPRKGEERPKFVSDSTLE-------EFKITDEG-----------ELRLTVKV 686

Query: 3585 NDSSM-RVEWFHNGKPLLTGSRVK-TINDFGFVILEIGGVYQRDAGLYTCKATNRHGEAT 3642
                   VEW  + K L   +RV  +  D G V+L I  V   D+G+Y CK T+  G +T
Sbjct: 687  TGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTST 746

Query: 3643 VSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIK 3702
             S  + ++G              +   + + ++++T+       +ED    P        
Sbjct: 747  KSFDVTIEGE-------------RRKAKKLIEVDDTVAPH---FVEDTSIAP-------- 782

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GFIALDIDYIY 3761
               ++ + G V    RV   G P     W  +       S  +T       + L +    
Sbjct: 783  --FELTDSGDVRLSVRV--AGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIVKSPS 838

Query: 3762 ARDAGEYTCRATNKWGSATTTAKI 3785
              D G Y C ATNK G+ T T ++
Sbjct: 839  PSDQGTYKCTATNKGGTVTRTFQV 862



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 58/245 (23%), Positives = 101/245 (41%), Gaps = 12/245 (4%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            LK   A EG  + F+ R+   G P   +EW KN + ++ S +F  I        ++ SL 
Sbjct: 2211 LKDTEANEGDVVRFDIRV--AGKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLV 2268

Query: 703  I-----QDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQ 757
            I     +D   Y+  A++  G   +K  L V  +   E  +Q       ++ L +     
Sbjct: 2269 IEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEV 2328

Query: 758  HQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASS 817
             +E      ++ P FI  ++++ E+ EG  A F+  +  V +P+  ++WY+    I    
Sbjct: 2329 PEEEAASPETKAPVFIETMKNI-EVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEG 2385

Query: 818  RITSI--FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
            R   I        +L I + +  D G YT  A N + E    A + V  +         P
Sbjct: 2386 RFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPKEIAPEFQKEP 2445

Query: 876  EQRRY 880
            E+  +
Sbjct: 2446 EKSTF 2450



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 3/165 (1%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            +G     +EW+ + + +                L I     +D+GTY C   N  G    
Sbjct: 1088 SGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYKCVTKNDSGTFTQ 1147

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
               +  V+K +G  P F   ++ +E + + Q    EC+V    +P  +I W   G  ++ 
Sbjct: 1148 MFDITIVEKPEGAAPEFIKPLKVLE-VFETQPVRLECSVTGTPEP--QITWLKGGDVVKE 1204

Query: 3195 STRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
              RI TV D    VL+I  +   D GEY C A N +G+  T A +
Sbjct: 1205 DDRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAEL 1249



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 66/246 (26%), Positives = 105/246 (42%), Gaps = 19/246 (7%)

Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746
            I +E  + P     +KD  +  EG  V FD RV   G P   ++WF N        +   
Sbjct: 2197 IVEEGISLPVIKEGLKDT-EANEGDVVRFDIRV--AGKPEPVVEWFKNDELLDDSGKFII 2253

Query: 3747 LNDFG-----FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP- 3800
            ++D         +L I+     D   Y+  A N+ G  ++  K+  ++K     E + P 
Sbjct: 2254 IDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKP----EQEAPA 2309

Query: 3801 QGMSGEKIKELERGRISDAPKEEPIV--STPPKFITQIKSHTVEESEGVRFECRVEPKED 3858
            Q  +   I E     I + P+EE     +  P FI  +K+  V E E  RF+  V+   +
Sbjct: 2310 QADAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPE 2369

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTV--YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTK 3916
            P   I+WYR  +L+P   R+  +        +L I      D+G+Y C A ND  E   +
Sbjct: 2370 PS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCE 2427

Query: 3917 ATISCK 3922
            A ++ K
Sbjct: 2428 AVLTVK 2433



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 71/278 (25%), Positives = 106/278 (38%), Gaps = 32/278 (11%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V    + P F TP+KDQ  ++EG     +  +E  G S + ++W KD + +    R T  
Sbjct: 1989 VESEAEPPRFVTPLKDQ-ELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFT 2045

Query: 962  FNFGYVALTIKSVTVHD-AGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020
             +     +TI  VT+ D A +Y   A N  G+A T A        ++I E +    +  +
Sbjct: 2046 KDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDA--------EVIVEVKEAAEVTPV 2097

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            + + DA+               P  + PL     ++EG S   E  +    D    V WY
Sbjct: 2098 EEVVDAA------------VPAPIIIKPLNDEIDVLEGDSVRLECVISGGPD--AQVLWY 2143

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             +   +    RI    D     L I S   +D   Y  V  N AG   +   + VE    
Sbjct: 2144 KDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVE--EG 2201

Query: 1141 IDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPV 1178
            I    I  GL  K     E   V   + I    K +PV
Sbjct: 2202 ISLPVIKEGL--KDTEANEGDVVR--FDIRVAGKPEPV 2235



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 94/395 (23%), Positives = 161/395 (40%), Gaps = 56/395 (14%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P   V W KDG+P+     +          L I     +D+GSY     + +G++  T S
Sbjct: 203  PEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFS 262

Query: 860  IRVAARSTVTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQI 919
            + + +      +    E+R+ ++                   V +ST + EFK  I D+ 
Sbjct: 263  VDIESEGPAPKE---SEKRKLLK------------GEERPKFVSDSTVE-EFK--ITDEG 304

Query: 920  SIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR-ITTFFNFGYVALTIKSVTVHD 978
             ++          ++  G     VEW KD + ++   R I +  + G V L IK V  HD
Sbjct: 305  ELR--------LTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHD 356

Query: 979  AGHYTCRAYNAIGQATTSANLTIV---TKKDIIAESQHPGGLEK-IQYLEDASRYSKRTE 1034
            +G Y C+  + +G +T S ++TI     K   + E      LEK I+++++     +   
Sbjct: 357  SGVYKCQVSSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEPVPEEQVMP 416

Query: 1035 EEVKITQ----KPRFL----GPLKGTNKIVEGQSAH-FEARVEPQSDLTM--------TV 1077
             +VK  +    KPR +      LK     +E      FE   E    +T         +V
Sbjct: 417  TKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQVTGKPQPSV 476

Query: 1078 EWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV-E 1136
            EW+ +   ++    I    + G  +L I     +D G YTV   N AG  + +  ++V +
Sbjct: 477  EWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDD 536

Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEE 1171
            TR +I   ++      K + IE+  FV P    +E
Sbjct: 537  TRKTIPKDAV------KPKFIEDGSFV-PFQSTDE 564



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 60/236 (25%), Positives = 98/236 (41%), Gaps = 40/236 (16%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F  P+K + V E Q    E  +   G P+ ++ WL+ G  ++  +R+TT+ D     
Sbjct: 1161 APEFIKPLKVLEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDRITTVFDGETCV 1218

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829
            LN+     +D G Y C A+N+ G+A T + L V              AL K + +E +  
Sbjct: 1219 LNITVSCLDDEGEYKCLAMNDFGKAATVAELLV------------NEALVKPKFIETT-- 1264

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
                 D E+   ++  F  +  G                 P PD    V+WY    ++  
Sbjct: 1265 ----HDTEIITGESVWFRVKYEG----------------SPTPD----VDWYHEDTLVSD 1300

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
              R+  + +   + L I  V   D G Y C   N+ G+ ++  +L V  K+  I D
Sbjct: 1301 TGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITD 1356



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 62/239 (25%), Positives = 108/239 (45%), Gaps = 40/239 (16%)

Query: 1837 EVAVNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY 1893
            E+ VN+A   P+FI +    T++  G+S  +  + E  P P+  V+WY    ++    R+
Sbjct: 1248 ELLVNEALVKPKFI-ETTHDTEIITGESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRF 1304

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
              + +   + L I  V   D G Y C   N+ G+ ++  +L V               +E
Sbjct: 1305 LINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTV---------------IE 1349

Query: 1954 KIQYLEDDSRYKRAVQDDSFVVE-KPQFGK-PIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
            K          K+ + D     E  P  G+ P+K   +++G  + LE  +T   +P   +
Sbjct: 1350 K----------KKPITDVGTPPEFSPHVGEGPLK---ISDGGDLTLEVKIT--GEPKPEI 1394

Query: 2012 EWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            +W+ + +PV+   + +  Y     +L I+ A  +DT  Y CKATN  G   TT ++ VD
Sbjct: 1395 QWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG--TTTRNINVD 1451



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 156/701 (22%), Positives = 268/701 (38%), Gaps = 96/701 (13%)

Query: 3662 PSHFKSGTESIQKLEET-LHKRE-EITIEDEKPNPPRFTVE---IKDNIDVPEGGPVHFD 3716
            P+    GT +++   E  L +R  +++++D +   P+  V+   I+D   VP       D
Sbjct: 133  PTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGD 192

Query: 3717 CR--VEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
             R  V+  G P   + W  +G+P      V   +      L I      D+G Y C  T+
Sbjct: 193  VRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTS 252

Query: 3775 KWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFIT 3834
              G +T T  +         +ES+ P     EK ++L +G       EE      PKF++
Sbjct: 253  DVGKSTRTFSVD--------IESEGPAPKESEK-RKLLKG-------EER-----PKFVS 291

Query: 3835 Q--IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR-TVYDMGFVSLDI 3891
               ++   + +   +R   +V  K  P+  +EW ++ K L    R   +  D G V L I
Sbjct: 292  DSTVEEFKITDEGELRLTVKVTGKPFPE--VEWTKDDKDLKEDDRVIISEQDDGIVVLRI 349

Query: 3892 LYVYAEDSGEYICRAVNDFGEDFTKA---TI-----SCKKLPDIILQNQVPRGMKRSEAL 3943
              V A DSG Y C+  +D G   TK+   TI       KKL ++     + + +K  +  
Sbjct: 350  KDVGAHDSGVYKCQVSSDVGTS-TKSFDVTIEGERRKAKKLIEVDETEHLEKRIKHVKEP 408

Query: 3944 TQMEATIKKYTSEVYLTED---DLYDVDK--KQPPRFVTQIQSQT-SLVEMETTKFECQL 3997
               E  +      V    D    + +VD   K+ P F+   + +   + E    K   Q+
Sbjct: 409  VPEEQVMPTKVKPVETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQV 468

Query: 3998 APVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057
               G P   VEWF +  P+      T   + G  ++       +D G Y    +N  G+ 
Sbjct: 469  --TGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLG 526

Query: 4058 ETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLP 4117
                           +D  +    K+I K    +A   V P+ + + S       FV   
Sbjct: 527  RR------------TFDVSVDDTRKTIPK----DA---VKPKFIEDGS-------FVPFQ 560

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYD 4176
               + +EG+  R   +VTG P+P V W  +G  +      +L + +  Y   I +    D
Sbjct: 561  ---STDEGD-VRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDD 616

Query: 4177 TGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFE 4236
            +G                  + +  +    +   K  PR         +R +   + T E
Sbjct: 617  SGSYRCTLTSDVGKSTRTFSVDIESKGPATKESEKKKPR------KGEERPKFVSDSTLE 670

Query: 4237 ERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLR 4296
            E ++   +G +  R  +K      PE EW +  K  K +   N++   E +  I   R++
Sbjct: 671  EFKITD-EGEL--RLTVKVTGKPFPEVEWTKDDKDLKED---NRVIISEQDDGIVVLRIK 724

Query: 4297 E-STHQYAIPGDKVTSN--TVAKSMAQRYEDNLDQTEEVTE 4334
            +   H   +   KVTS+  T  KS     E    + +++ E
Sbjct: 725  DVGAHDSGVYKCKVTSDVGTSTKSFDVTIEGERRKAKKLIE 765



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 66/243 (27%), Positives = 108/243 (44%), Gaps = 33/243 (13%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEAR--------LEPIGDSTLRVEWLKDGRPVEAS 955
            + T+K   K  +K +  I++G F  F++         ++  G     V W KDG+PV+  
Sbjct: 535  DDTRKTIPKDAVKPKF-IEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKL 593

Query: 956  SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPG 1015
              +          LTI+  +  D+G Y C   + +G++T + ++ I +K     ES+   
Sbjct: 594  PNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESKGPATKESEK-- 651

Query: 1016 GLEKIQYLEDASRY-SKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLT 1074
              +K +  E+  ++ S  T EE KIT +    G L+ T K+          +  P+    
Sbjct: 652  --KKPRKGEERPKFVSDSTLEEFKITDE----GELRLTVKVT--------GKPFPE---- 693

Query: 1075 MTVEWYFNGKQITSANR-IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASM 1133
              VEW  + K +   NR I +  D G V L I  V A DSGVY     +  G +  S  +
Sbjct: 694  --VEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFDV 751

Query: 1134 TVE 1136
            T+E
Sbjct: 752  TIE 754



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 7/102 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG---- 1766
            PV   P+K + + E  AA F+ R+   G P+  VEW ++G  ++   R   + D      
Sbjct: 967  PVIIQPLKSLEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDK 1024

Query: 1767 -YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
               +L ++ V PED+G Y C A+NE G+A +++TL V +K S
Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKIS 1066



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 58/207 (28%), Positives = 83/207 (40%), Gaps = 14/207 (6%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFG-----FVILEIGGVYQRDAGLYTCKATNRHGEATVSC 3645
            VEWF N + L    +   I+D          L I G    D  +Y+  A N  G+ +   
Sbjct: 2236 VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKG 2295

Query: 3646 KLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNI 3705
            KL V  +     E + P+   + T  ++ L ET+ +  E      +   P F +E   NI
Sbjct: 2296 KLLVNSKP----EQEAPAQADAATPILEPLVETIPEVPEEEAASPETKAPVF-IETMKNI 2350

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VH-TLNDFGFIALDIDYIYAR 3763
            +V EG    FD  V+ V +P+  IDW+          R VH          L I+     
Sbjct: 2351 EVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLG 2408

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAK 3790
            D G+YTC A N     T  A +T   K
Sbjct: 2409 DTGKYTCIAANDVDEITCEAVLTVKPK 2435



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 2/93 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F KP+K  EV E  PV LE ++T   +P  ++ W   G  V++  R  T +D     L
Sbjct: 1162 PEFIKPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITTVFDGETCVL 1219

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            +I  +  +D G Y C A N  G+A T + + V+
Sbjct: 1220 NITVSCLDDEGEYKCLAMNDFGKAATVAELLVN 1252



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 3410 TSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRF 3469
            T VE+ +G AP F  PL  +E + E +    E  +T T +P  ++ W   G  +K   R 
Sbjct: 1152 TIVEKPEGAAPEFIKPLKVLE-VFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRI 1208

Query: 3470 RTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
             T  D    +L I+ +  +D GEY C A N++G+A T A + V
Sbjct: 1209 TTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 2/90 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+FI  +K   V E++ VR EC V    +P+  I W + G ++    R  TV+D     L
Sbjct: 1162 PEFIKPLKVLEVFETQPVRLECSVTGTPEPQ--ITWLKGGDVVKEDDRITTVFDGETCVL 1219

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            +I     +D GEY C A+NDFG+  T A +
Sbjct: 1220 NITVSCLDDEGEYKCLAMNDFGKAATVAEL 1249



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 61/229 (26%), Positives = 90/229 (39%), Gaps = 16/229 (6%)

Query: 3983 TSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG-----YVAMNFGW 4037
            T   E +  +F+ ++A  G P   VEWF N + L    +F  I D         ++    
Sbjct: 2214 TEANEGDVVRFDIRVA--GKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEG 2271

Query: 4038 VYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVT 4097
              PED   Y   A N  G D +K  +    KP     +Q       +E +  +E   +V 
Sbjct: 2272 CAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPL--VETIPEVP 2329

Query: 4098 PEQVVE-ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
             E+    E+KA   PVF+     + V EGE ARF   V G P+P + W      I +  R
Sbjct: 2330 EEEAASPETKA---PVFIETMKNIEVMEGEEARFDVHVDGVPEPSIDWYRGEELIPDEGR 2386

Query: 4157 Y---KLTYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
            +       + ++   I  T+  DTGK   I             L V P+
Sbjct: 2387 FVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 57/228 (25%), Positives = 98/228 (42%), Gaps = 26/228 (11%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            +E  E +  PPRFVT L+    + EG T   +  VE      + I+++ + K L    R 
Sbjct: 1986 LEAVESEAEPPRFVTPLK-DQELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERH 2042

Query: 2292 HITFDFGYVSLDIQHCVPED-AGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGL 2350
              T D    ++ I     ED A  Y V A N  G   +   + V  K     E+     +
Sbjct: 2043 TFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK-----EAAEVTPV 2097

Query: 2351 EKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKV 2410
            E++  +++A P              P+  +PL +  ++ EG +   +C  +  G P  +V
Sbjct: 2098 EEV--VDAAVP-------------APIIIKPLNDEIDVLEGDSVRLEC--VISGGPDAQV 2140

Query: 2411 EWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             W++++ L+E+  RI    D    ++ I     +DE  Y C  +N+ G
Sbjct: 2141 LWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 57/258 (22%), Positives = 116/258 (44%), Gaps = 41/258 (15%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            KP F++  ++   +  G+++    + E  G PT  V+W+H    V+   RF         
Sbjct: 1257 KPKFIET-THDTEIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRF--------- 1304

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
               +I+ T  DT    +  V  +   +   I+          D   +  + ++ ++E   
Sbjct: 1305 ---LIN-TEEDTSTLIIEDVKPIDKGNYKCIIS--------NDAGEDMTVSKLTVIE--- 1349

Query: 1296 RRTKQVREDITVMQAPQFSRALHN--IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI 1353
             + K + +   V   P+FS  +    ++  +G ++ LE ++   G+    ++WF + KP+
Sbjct: 1350 -KKKPITD---VGTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPV 1403

Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQ 1413
            K   + R  Y  D  +L ++   P+D+  YTC+ATN+ G    +  + + A   L+ E +
Sbjct: 1404 KPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISA---LMPEGE 1460

Query: 1414 HPSGLEKI---QYLEDTS 1428
             P  +E +   + +ED+S
Sbjct: 1461 APKYVEPLKSDEIVEDSS 1478



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 73/332 (21%), Positives = 132/332 (39%), Gaps = 26/332 (7%)

Query: 61   ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
            IT     E + P F +  K     +    + E  + G P P ++W +    + E ++ + 
Sbjct: 1151 ITIVEKPEGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITT 1210

Query: 121  RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAIC-SVYIQPEGXXXXXXXXXXXXXY 179
             ++ +T  +++ +  +   DEGEY C A N +G+A   +  +  E               
Sbjct: 1211 VFDGETCVLNITVSCLD--DEGEYKCLAMNDFGKAATVAELLVNEALVKPKFIETTHDTE 1268

Query: 180  RHVSETV--EHKAYGTQGYTTEQSRQTQKVAYT-----NGTDHSST---DDFK-VDTFEY 228
                E+V    K  G+     +   +   V+ T     N  + +ST   +D K +D   Y
Sbjct: 1269 IITGESVWFRVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNY 1328

Query: 229  RLLREVSFRESIT--KRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQ 286
            + +      E +T  K  V E    I+   D    P   P + + P   K+ +G D   +
Sbjct: 1329 KCIISNDAGEDMTVSKLTVIEKKKPIT---DVGTPPEFSPHVGEGPL--KISDGGDLTLE 1383

Query: 287  VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC 346
            V+++G P+P + WFK+ + +  S K  +    +  +L +      D+  YT  A N +G 
Sbjct: 1384 VKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGT 1443

Query: 347  I-----VTSGYLAVESPTESYVQDQRSQYITD 373
                  V    L  E     YV+  +S  I +
Sbjct: 1444 TTRNINVDISALMPEGEAPKYVEPLKSDEIVE 1475



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 56/226 (24%), Positives = 94/226 (41%), Gaps = 11/226 (4%)

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI--LTVYG 1911
            T+ +EG    ++ R+   P+P   VEW+ N ++L    ++   +D      ++  L + G
Sbjct: 2214 TEANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEG 2271

Query: 1912 ---EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAV 1968
               ED   Y+  A+N  G+  S  +L V SK      +Q ++A   ++ L +        
Sbjct: 2272 CAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVPEE 2331

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK- 2027
            +  S   + P F + +KN EV EG     +  +  V +P+  ++WY     +    RF  
Sbjct: 2332 EAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRFVH 2389

Query: 2028 -TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
                      L I      DTG Y C A N V E    + + V  K
Sbjct: 2390 IDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 68/274 (24%), Positives = 108/274 (39%), Gaps = 41/274 (14%)

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            + L +     +D GTY C ATNK G       V +E +D      P+   + + IE + +
Sbjct: 830  LTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQVNMEGIDTG----PQIQEYSKEIE-VVE 884

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G S   EC     +D   +I WY +  P+  S R +T  D G   L I      D  EY 
Sbjct: 885  GSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEYR 942

Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPK 3283
            C      G      T     +  V    L P  +  ++ LE  +    +        P  
Sbjct: 943  CDIATDRG--VVSMTTELIVEEAV----LMPVIIQPLKSLEIKEENAARFDVRVRGSPQP 996

Query: 3284 FITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343
             +   +D      G+      R + +DD D + +  Y+                 +VI D
Sbjct: 997  LVEWFKD------GRQLQDLGRFMIIDDVDDQDKELYS-----------------LVIED 1033

Query: 3344 ILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
            ++    E++GEYECVA N+ G+ ++ A L+  +K
Sbjct: 1034 VI---PEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 102/437 (23%), Positives = 155/437 (35%), Gaps = 83/437 (18%)

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360
            SL I+ C P+D   YSV A+N  G  TS        KG ++  S                
Sbjct: 1846 SLVIEGCAPDDDAVYSVVAMNEAGKDTS--------KGKLLVHS---------------- 1881

Query: 2361 PFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIE 2420
               RP+  +P     P  T+ L + + ++E          +  G+ +  V W ++   + 
Sbjct: 1882 ---RPKQEQPTEPAGPRITKELVDAE-VEETTPVTLVAEFVSEGETS--VTWTKDAHRVV 1935

Query: 2421 DSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQH 2480
              +R+T   D    ++ IS    +DEG+Y C   N +G+              ++ E   
Sbjct: 1936 ADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEA-- 1993

Query: 2481 PEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSL 2540
                               EP R F  P+  Q      EL EG     +  V   G   +
Sbjct: 1994 -------------------EPPR-FVTPLKDQ------ELEEGSTV--DMLVETDGTSPI 2025

Query: 2541 RFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYM-CKAINRAGXXXXXXXXX 2599
              +W+ +  EL    R   T D    T+ I+ V   D  +Y    A N AG         
Sbjct: 2026 HIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVI 2085

Query: 2600 XXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQH 2659
                               +++KEAA     E  VD  V  API    L     ++EG  
Sbjct: 2086 -------------------VEVKEAAEVTPVEEVVDAAVP-APIIIKPLNDEIDVLEGDS 2125

Query: 2660 VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKA 2719
            V LE  +     P+ ++ W+K+   L    R+    D    TL I S   DD   Y C  
Sbjct: 2126 VRLECVISG--GPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVV 2183

Query: 2720 TNLLGEAVSTASIKIED 2736
            TN+ G       + +E+
Sbjct: 2184 TNIAGSVDVKTELIVEE 2200



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 72/282 (25%), Positives = 117/282 (41%), Gaps = 48/282 (17%)

Query: 1401 RVIAKKDLILESQHPS--GLEKIQYLEDTSRYKKTDIID-ESVTIKPRFVTRPKSIENVI 1457
            RV  +  LI++S  PS  G  K           +T  ++ E +   P+     K IE V+
Sbjct: 825  RVDDRLTLIVKSPSPSDQGTYKCTATNKGGTVTRTFQVNMEGIDTGPQIQEYSKEIE-VV 883

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EG  V  EC+     D+  ++ W+K+  P+    RF                 A D+G+ 
Sbjct: 884  EGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFET---------------AFDNGLC 926

Query: 1518 TCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA 1577
            + R  ++V  DE   R    +   +V  T                    T+++ E     
Sbjct: 927  SLRIHDIVIDDEAEYRCDIATDRGVVSMT--------------------TELIVEEAVLM 966

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF-----TETNNF 1632
            P+    LK++EIKE   A F+ R +  S   L VEW+ + + L+   RF      +  + 
Sbjct: 967  PVIIQPLKSLEIKEENAARFDVR-VRGSPQPL-VEWFKDGRQLQDLGRFMIIDDVDDQDK 1024

Query: 1633 GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674
               +L I   +PED+G Y C A+N  G+A ++    V +K S
Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKIS 1066



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 63/288 (21%), Positives = 112/288 (38%), Gaps = 36/288 (12%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F     D  +   ++  F  +    G P   V+W      +  + R     +     L
Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKY--EGSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTL 1315

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRY 1830
             ++ V P D G Y C   N+ GE +T S L V               ++K + + D    
Sbjct: 1316 IIEDVKPIDKGNYKCIISNDAGEDMTVSKLTV---------------IEKKKPITD---- 1356

Query: 1831 QRREDVEVAVNQAPRFITQLN-GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
                     V   P F   +  GP K+S+G     E +I   P P   ++W+ + K ++ 
Sbjct: 1357 ---------VGTPPEFSPHVGEGPLKISDGGDLTLEVKITGEPKPE--IQWFKDDKPVKP 1405

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHE 1949
              + R        +L I+    +D+ +YTCKA N  G    +I +++ +        ++ 
Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGEAPKYV 1465

Query: 1950 SALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHL 1997
              L+  + +ED S +   V+     + + Q+ K  +N  V E   VH+
Sbjct: 1466 EPLKSDEIVEDSS-FTMNVKFTGTPIPEVQWFK--ENKPVREDDRVHI 1510



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 61/266 (22%), Positives = 107/266 (40%), Gaps = 32/266 (12%)

Query: 1566 RTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNN-KPLKSGS 1624
            +T+++ E     P+    LK+ E  EG+   F+ R+    +  L      +  K L    
Sbjct: 1775 KTELIVEEGISLPVIKEGLKDTEANEGEIVRFDIRVAGKPEPWLNGSRMTSLWKILFIII 1834

Query: 1625 RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGA 1684
               +  +    +L I  C P+D   Y+  A+N  G+  + G  +VHS+     E   E A
Sbjct: 1835 DDVDDKDKELFSLVIEGCAPDDDAVYSVVAMNEAGKDTSKGKLLVHSRPK--QEQPTEPA 1892

Query: 1685 LPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRV 1744
             PR+                         T  + D  V E       A  +  G+    V
Sbjct: 1893 GPRI-------------------------TKELVDAEVEETTPVTLVAEFVSEGETS--V 1925

Query: 1745 EWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             W ++   + A NR+T   D     L +   + +D G YTC   N++G+  TS+ + V+ 
Sbjct: 1926 TWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEE 1985

Query: 1805 KASLQLESQHESALQ--KIQQLEDSS 1828
              +++ E++    +   K Q+LE+ S
Sbjct: 1986 LEAVESEAEPPRFVTPLKDQELEEGS 2011



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 8/109 (7%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            + EE    PV   PL ++E ++E   A F+ R+  +  P   VEW+ +G+ L+   RF  
Sbjct: 959  IVEEAVLMPVIIQPLKSLE-IKEENAARFDVRVRGSPQP--LVEWFKDGRQLQDLGRFMI 1015

Query: 3472 FCDFG-----FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
              D          L I    PED+GEY C A N  G+A +TA+++V  K
Sbjct: 1016 IDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 37/108 (34%), Positives = 52/108 (48%), Gaps = 8/108 (7%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E+   P    P+K  + IKE   A F+ R+   G     VEW KDGR ++   R    
Sbjct: 960  VEEAVLMPVIIQPLKS-LEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMII 1016

Query: 962  FNFG-----YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
             +         +L I+ V   DAG Y C A N  G+AT++A L ++TK
Sbjct: 1017 DDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 89/390 (22%), Positives = 138/390 (35%), Gaps = 63/390 (16%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            KP+F +   + E+  G  V           PT  V+WY     V    RF    +     
Sbjct: 1257 KPKFIETTHDTEIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRFLINTEEDTST 1314

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096
            L I      D G Y C  +N  GE +T S + V                         E+
Sbjct: 1315 LIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTV------------------------IEK 1350

Query: 2097 PKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156
             KPI +   G  P F   +     LK  D       V+   +P   I WF + + ++   
Sbjct: 1351 KKPITDV--GTPPEFSPHVGE-GPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQ 1407

Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNG 2216
            + R  +     +L I+    +D+  Y CKATNK G    T T      RNI +D      
Sbjct: 1408 KIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG----TTT------RNINVD------ 1451

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276
               I  L  +G +            P++V  L+    V   + + F   V+    P   +
Sbjct: 1452 ---ISALMPEGEA------------PKYVEPLKSDEIV---EDSSFTMNVKFTGTPIPEV 1493

Query: 2277 EFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
            +++   K ++   R HI  +    +L I   VP+D G Y +   N  G   S   + V  
Sbjct: 1494 QWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMT 1553

Query: 2337 KGSIISESQRPEGLEKIRELESAEPFKRPE 2366
                  E   P+      + E   P ++P+
Sbjct: 1554 VSEAEDEGIIPKVTPTPGKTEITIPGQKPK 1583



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 80/360 (22%), Positives = 139/360 (38%), Gaps = 70/360 (19%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F +PL+ ++ + E Q    +C +   G P  ++ W +   ++++  RIT   D     
Sbjct: 1162 PEFIKPLKVLE-VFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDRITTVFDGETCV 1218

Query: 2436 MTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE 2495
            + I+    +DEG Y C A N  G+                 E    E + K + +E  H+
Sbjct: 1219 LNITVSCLDDEGEYKCLAMNDFGKAATVA------------ELLVNEALVKPKFIETTHD 1266

Query: 2496 RRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGS 2555
                           T+++TG S +W         RV   G P+   +WY     +    
Sbjct: 1267 ---------------TEIITGES-VW--------FRVKYEGSPTPDVDWYHEDTLVSDTG 1302

Query: 2556 RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPES 2615
            RF    +    TL I  V   D G Y C   N AG                         
Sbjct: 1303 RFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAG------------------------- 1337

Query: 2616 WEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHL-KSYDKLVEGQHVYLEAQVEPRTDPNL 2674
             E + + +  + +  +   D G    P F+ H+ +   K+ +G  + LE ++    +P  
Sbjct: 1338 -EDMTVSKLTVIEKKKPITDVGT--PPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKP 1392

Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +I+WFK+   +    +++  +   + +L+I     DD+  YTCKATN  G      ++ I
Sbjct: 1393 EIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDI 1452



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 8/111 (7%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E I E+    P  I+PL+ L E++E   A F+ ++     P   VEW+KDGR +    R 
Sbjct: 957  ELIVEEAVLMPVIIQPLKSL-EIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRF 1013

Query: 820  TSIFNFG-----YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
              I +         SL I  +  EDAG Y   AVN+ G+A STA+++V  +
Sbjct: 1014 MIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 54/220 (24%), Positives = 93/220 (42%), Gaps = 34/220 (15%)

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            KP+F+     T +I+ G+S  F  RV+ +   T  V+WY     ++   R     +    
Sbjct: 1257 KPKFIETTHDT-EIITGESVWF--RVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTS 1313

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161
             L I  V+  D G Y  +  N AGE    + +TV                     IE+ K
Sbjct: 1314 TLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTV---------------------IEKKK 1352

Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPP-PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSV 1220
               P+  +     + P F   +   P  +S+G ++ LE ++   G+P   ++WF + + V
Sbjct: 1353 ---PITDV----GTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPV 1403

Query: 1221 TVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
                + +  Y     +L I+ A+  DT +YT +A N  G+
Sbjct: 1404 KPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGT 1443



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 8/110 (7%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P  I PLKS+   E     F+ R+   G P   +EW K+G+ ++   RF  I        
Sbjct: 967  PVIIQPLKSLEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDK 1024

Query: 697  DMLSLNIQD-----SGEYTCRAVSATGVAETKAVLHV-TPRATIERTSQH 740
            ++ SL I+D     +GEY C AV+  G A + A L V T  + +++T  H
Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKISELDKTPVH 1074



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+FI PLK +   E   +  E  +   G P  +I WLK G  ++   R T++F      L
Sbjct: 1162 PEFIKPLKVLEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDRITTVFDGETCVL 1219

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            ++    + D GEY C A++  G A T A L V
Sbjct: 1220 NITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 9/123 (7%)

Query: 909  PEFKTPIKD-QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            PEF   + +  + I +GG    E ++   G+    ++W KD +PV+ S +I   +     
Sbjct: 1361 PEFSPHVGEGPLKISDGGDLTLEVKIT--GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIH 1418

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI---QYLE 1024
            +LTI   +  D   YTC+A N  G  T + N+ I     ++ E + P  +E +   + +E
Sbjct: 1419 SLTIVGASPDDTAKYTCKATNKSGTTTRNINVDI---SALMPEGEAPKYVEPLKSDEIVE 1475

Query: 1025 DAS 1027
            D+S
Sbjct: 1476 DSS 1478



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 3/101 (2%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            +E+     P+FI+PL+ L E+ E +    E  +T   +P  ++ W K G  +    RIT+
Sbjct: 1154 VEKPEGAAPEFIKPLKVL-EVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITT 1210

Query: 822  IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            +F+     LNI     +D G Y   A+N  G+A + A + V
Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 65/289 (22%), Positives = 109/289 (37%), Gaps = 34/289 (11%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P+F    H+ E + G +V    + +  G  T  V+W+     +    RF    E D   L
Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRFLINTEEDTSTL 1315

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRY 1430
             +  V P D G Y C  +N  GE +T         K  ++E + P               
Sbjct: 1316 IIEDVKPIDKGNYKCIISNDAGEDMT-------VSKLTVIEKKKPI-------------- 1354

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
              TD+        P     P  I    +G  +  E K+    +   +++WFK+ +PV   
Sbjct: 1355 --TDV-GTPPEFSPHVGEGPLKIS---DGGDLTLEVKI--TGEPKPEIQWFKDDKPVKPS 1406

Query: 1491 HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             + R  +     +L I+    +D+  YTC+A N  GT   +  +   +      + +   
Sbjct: 1407 QKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGEAPKYVE 1466

Query: 1551 GLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFER 1599
             L+  +++ED S    T  V    T  P      +N  ++E  R H  R
Sbjct: 1467 PLKSDEIVEDSS---FTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIR 1512



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 58/252 (23%), Positives = 100/252 (39%), Gaps = 13/252 (5%)

Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228
            I E   S PV  + L +    +EG  +  + R+   G P   VEWF N   +    +F  
Sbjct: 2197 IVEEGISLPVIKEGLKDTE-ANEGDVVRFDIRVA--GKPEPVVEWFKNDELLDDSGKFII 2253

Query: 1229 YYDFG-----FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQ 1283
              D         +L I      D   Y+V A+N  G   +   + V  + +     Q + 
Sbjct: 2254 IDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADA 2313

Query: 1284 AIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMR 1343
            A   ++ L +      +        +AP F   + NIE +EG     +  +  V + +  
Sbjct: 2314 ATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPS-- 2371

Query: 1344 VEWFCNGKPIKTGHRF--RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
            ++W+   + I    RF    A + +   L + +    D+G YTC A N + E +T  A+ 
Sbjct: 2372 IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDE-ITCEAVL 2430

Query: 1402 VIAKKDLILESQ 1413
             +  K++  E Q
Sbjct: 2431 TVKPKEIAPEFQ 2442



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 32/95 (33%), Positives = 51/95 (53%), Gaps = 7/95 (7%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG---- 3885
            P  I  +KS  ++E    RF+ RV  +  P+  +EW+++G+ L    R+  + D+     
Sbjct: 967  PVIIQPLKSLEIKEENAARFDVRV--RGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDK 1024

Query: 3886 -FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               SL I  V  ED+GEY C AVN+ G+  + AT+
Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATL 1059



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 58/243 (23%), Positives = 97/243 (39%), Gaps = 32/243 (13%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E++E + ++ P+F+ PL+D  EL+EG       + T  + P + ++W+KD + +    R 
Sbjct: 1987 EAVESE-AEPPRFVTPLKDQ-ELEEGSTVDMLVE-TDGTSP-IHIKWFKDNKELVPDERH 2042

Query: 820  TSIFNFGYVSLNIMHLRAED-AGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQR 878
            T   +    ++ I  +  ED A  Y V A N  GEA++ A + V  +    A++   E+ 
Sbjct: 2043 TFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKE--AAEVTPVEE- 2099

Query: 879  RYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGD 938
                                   V  +   P    P+ D+I + EG     E  +   G 
Sbjct: 2100 ----------------------VVDAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS--GG 2135

Query: 939  STLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSAN 998
               +V W KD   +E   RI    +     L I+S  + D   Y C   N  G       
Sbjct: 2136 PDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTE 2195

Query: 999  LTI 1001
            L +
Sbjct: 2196 LIV 2198



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 61/235 (25%), Positives = 91/235 (38%), Gaps = 25/235 (10%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P F  P+KD  + E      +  +   G   + ++W ++   +    R T   D    
Sbjct: 1994 EPPRFVTPLKDQELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKH 2051

Query: 1769 ALNMKYVNPEDSGTY-TCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDS 1827
             + +  V  ED   Y    A N  GEAVT + + V+ K         E+A  ++  +E  
Sbjct: 2052 TMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK---------EAA--EVTPVE-- 2098

Query: 1828 SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887
                  E V+ AV  AP  I  LN    + EG S   EC I   PD   +V WY +  +L
Sbjct: 2099 ------EVVDAAV-PAPIIIKPLNDEIDVLEGDSVRLECVISGGPD--AQVLWYKDDYLL 2149

Query: 1888 QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            +   R     D     L I +   +D  EY C   N  G       L V+   S+
Sbjct: 2150 EEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISL 2204



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 41/153 (26%), Positives = 71/153 (46%), Gaps = 12/153 (7%)

Query: 2197 CTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256
            C+L++    +I++D +     +          +T + VEE  + P   +  L+ +  + E
Sbjct: 926  CSLRI---HDIVIDDEAEYRCDIATDRGVVSMTTELIVEEAVLMPV-IIQPLK-SLEIKE 980

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG-----YVSLDIQHCVPED 2311
               A F+ +V     P   +E++ +G+ LQ   RF I  D         SL I+  +PED
Sbjct: 981  ENAARFDVRVRG--SPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPED 1038

Query: 2312 AGEYSVKAINALGHCTSAISMTVTAKGSIISES 2344
            AGEY   A+N  G  TS  ++ V  K S + ++
Sbjct: 1039 AGEYECVAVNEAGKATSTATLQVLTKISELDKT 1071



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 53/217 (24%), Positives = 89/217 (41%), Gaps = 32/217 (14%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+F +E   + ++  G  V F  RV+  G PT  +DW+H     +   R     +     
Sbjct: 1258 PKF-IETTHDTEIITGESVWF--RVKYEGSPTPDVDWYHEDTLVSDTGRFLINTEEDTST 1314

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L I+ +   D G Y C  +N  G   T +K+T       V+E + P       I +    
Sbjct: 1315 LIIEDVKPIDKGNYKCIISNDAGEDMTVSKLT-------VIEKKKP-------ITD---- 1356

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
             +   P+  P V   P          ++ S+G      V+   +PK  I+W+++ K +  
Sbjct: 1357 -VGTPPEFSPHVGEGP----------LKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKP 1405

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
              + R  Y     SL I+    +D+ +Y C+A N  G
Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG 1442



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 58   RQPIT-AGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECN 116
            ++PIT  G P E SP + E   K    + GG+   E K+ G P P + W +   P+    
Sbjct: 1351 KKPITDVGTPPEFSPHVGEGPLK---ISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQ 1407

Query: 117  KYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
            K  + Y +     SL I    P D  +YTC A N+ G
Sbjct: 1408 KIRVDYRDDIH--SLTIVGASPDDTAKYTCKATNKSG 1442



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 78/344 (22%), Positives = 123/344 (35%), Gaps = 59/344 (17%)

Query: 1469 EPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
            E V++    V W K+   V   +R     D     L I     +D G+YTC   N +G  
Sbjct: 1916 EFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDT 1975

Query: 1529 EVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVE 1588
                            ST  E  +E+++ +E  +             + P   T LK+ E
Sbjct: 1976 ----------------STSAEVIVEELEAVESEA-------------EPPRFVTPLKDQE 2006

Query: 1589 IKEGQRAHFERRLIPVSDAT--LKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPED 1646
            ++EG        ++  +D T  + ++W+ +NK L    R T T +     + I     ED
Sbjct: 2007 LEEGSTVD----MLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLED 2062

Query: 1647 SGT-YTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDE 1705
                Y   A N  GEAVT    IV  K++  +    E                      +
Sbjct: 2063 EAMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTPVEEVV--------------------D 2102

Query: 1706 VITQAPVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
                AP+   P+ D I V E  +   E   +  G P  +V W ++   +E   R+    D
Sbjct: 2103 AAVPAPIIIKPLNDEIDVLEGDSVRLEC--VISGGPDAQVLWYKDDYLLEEDERIMYDTD 2160

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
                 L ++    +D   Y C   N  G     + L V+   SL
Sbjct: 2161 GDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISL 2204



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG--- 2165
            PV +  L SLE +KE + A F+ RV     P   ++WF +G++++   R+    D     
Sbjct: 967  PVIIQPLKSLE-IKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023

Query: 2166 --YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                +L I     ED+G Y C A N+ G+A +T TL+V
Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQV 1061



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 73/342 (21%), Positives = 130/342 (38%), Gaps = 40/342 (11%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  ++ W K+G  +     ++         L+I     DDSG Y C  T+ +G++  T S
Sbjct: 203  PEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFS 262

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            + IE       E   P   ++   L                   F+S       K  D  
Sbjct: 263  VDIE------SEGPAPKESEKRKLLKGEERPK------------FVSDSTVEEFKITDEG 304

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTR-YKSTHDFSYVSLDITHTYEEDSGIYTCKA 2850
                 V+ +  P  ++EW  ++K L    R   S  D   V L I      DSG+Y C+ 
Sbjct: 305  ELRLTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQV 364

Query: 2851 TNSKGSATTSGSLRCTGD-----KNIYFD-TQHPQGKAGLEAVEQAEEARLAKGRRPSVP 2904
            ++  G++T S  +   G+     K I  D T+H + +  ++ V++          +    
Sbjct: 365  SSDVGTSTKSFDVTIEGERRKAKKLIEVDETEHLEKR--IKHVKEPVPEEQVMPTKVKPV 422

Query: 2905 DTEYPKPEWIIPIAA----EHQLVEGQVLH-----LEGQV----EPKNDPDLKIEWYFNG 2951
            +T+  KP  I  + A    E   +E   +       EG +    +    P   +EW+ + 
Sbjct: 423  ETKVDKPRQIEEVDAMLKEEPTFLESDEIKPFEVTEEGDIKMTAQVTGKPQPSVEWFKDD 482

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
              +       +T + G  +L + +  ++D G YT +  N+ G
Sbjct: 483  VPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAG 524



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 56/259 (21%), Positives = 100/259 (38%), Gaps = 43/259 (16%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSD--LILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT 3602
            ++   P  + G PPEF+    +  L +S+      E ++    +    ++WF + KP+  
Sbjct: 1348 IEKKKPITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPVKP 1405

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662
              +++         L I G    D   YTCKATN+ G  T +  + +     ++ E + P
Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDI---SALMPEGEAP 1462

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
             +       ++ L     K +EI +ED       FT+ +K       G P+         
Sbjct: 1463 KY-------VEPL-----KSDEI-VEDSS-----FTMNVKFT-----GTPI--------- 1490

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
                  + WF   +P     RVH + +     L I      D G Y    +N +G A + 
Sbjct: 1491 ----PEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSE 1546

Query: 3783 AKITCSAKRDIVLESQLPQ 3801
            A++      +   E  +P+
Sbjct: 1547 AELVVMTVSEAEDEGIIPK 1565



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 49/210 (23%), Positives = 87/210 (41%), Gaps = 21/210 (10%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            DTG  P+     K+I ++ EG     E     +G +   I W+ +   +  S R  T + 
Sbjct: 868  DTG--PQIQEYSKEI-EVVEGSSVTIECQ--SSGAEDARITWYKDDVPLGDSPRFETAFD 922

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
             G+  L I      D   Y C      G   +S+  E + +     P     ++++E +K
Sbjct: 923  NGLCSLRIHDIVIDDEAEYRCDIATDRGV--VSMTTELIVEEAVLMPVIIQPLKSLE-IK 979

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD--------FGFVVLDIAYT 3214
            +  +A F+  V     P   +EW+ +G+ ++   R   + D        +  V+ D+   
Sbjct: 980  EENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVI-- 1035

Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATINCYGK 3244
               D+GEY C A N+ G+  + AT+    K
Sbjct: 1036 -PEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 7/92 (7%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFG-----FAALDILTV 1909
            ++ E  +A ++ R+   P P   VEW+ +G+ LQ   R+   +D         +L I  V
Sbjct: 977  EIKEENAARFDVRVRGSPQP--LVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDV 1034

Query: 1910 YGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
              ED+GEY C A+N  G+A S+  L V +K S
Sbjct: 1035 IPEDAGEYECVAVNEAGKATSTATLQVLTKIS 1066



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 53/239 (22%), Positives = 97/239 (40%), Gaps = 43/239 (17%)

Query: 3687 IEDEKP-----NPPRFTVEIKDN-IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            IE +KP      PP F+  + +  + + +GG +  + ++   G+P   I WF + +P   
Sbjct: 1348 IEKKKPITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPVKP 1405

Query: 3741 GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800
              ++         +L I      D  +YTC+ATNK  S TTT  I      ++ + + +P
Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNK--SGTTTRNI------NVDISALMP 1457

Query: 3801 QGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPK 3860
            +G               +APK          ++  +KS  + E     F   V+    P 
Sbjct: 1458 EG---------------EAPK----------YVEPLKSDEIVEDSS--FTMNVKFTGTPI 1490

Query: 3861 LRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
              ++W++  K +    R   + +    +L I     +D G Y     N FG+  ++A +
Sbjct: 1491 PEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAEL 1549



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 86/362 (23%), Positives = 131/362 (36%), Gaps = 54/362 (14%)

Query: 1964 YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023
            + R  Q+       P+  K + +AEV E  PV L A    V++    V W  +   V   
Sbjct: 1880 HSRPKQEQPTEPAGPRITKELVDAEVEETTPVTLVAEF--VSEGETSVTWTKDAHRVVAD 1937

Query: 2024 HRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQ 2083
            +R     D     L I  +  +D G Y C   N +G+  T++ V V              
Sbjct: 1938 NRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIV-------------- 1983

Query: 2084 RLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTI 2143
                 +ELE  E      E +P   P F+T L   E L+EG     +  VE      + I
Sbjct: 1984 -----EELEAVE-----SEAEP---PRFVTPLKDQE-LEEGSTV--DMLVETDGTSPIHI 2027

Query: 2144 DWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGT-YMCKATNKLGEAVNTCTLKVA 2202
             WF + +++    R+  T D     + I     ED    Y   A N  GEAV        
Sbjct: 2028 KWFKDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDA----- 2082

Query: 2203 GHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHF 2262
                +I++ +           EA   +   EV +  +  P  +  L     V EG +   
Sbjct: 2083 ---EVIVEVK-----------EAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRL 2128

Query: 2263 ECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINA 2322
            EC +     P+ ++ +Y +   L+   R     D    +L IQ    +D  EY     N 
Sbjct: 2129 ECVIS--GGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNI 2186

Query: 2323 LG 2324
             G
Sbjct: 2187 AG 2188



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 58/249 (23%), Positives = 93/249 (37%), Gaps = 24/249 (9%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY-----KSTHDFSYVSLD 2834
            L +    EGD + F+  V    +P   +EWF N++ L    ++         D    SL 
Sbjct: 2211 LKDTEANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLV 2268

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I     ED  +Y+  A N  G  ++ G L               Q  A    +E   E  
Sbjct: 2269 IEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPE---QEAPAQADAATPILEPLVET- 2324

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEH----QLVEGQVLHLEGQVEPKNDPDLKIEWYFN 2950
                  P VP+ E   PE   P+  E     +++EG+    +  V+    P+  I+WY  
Sbjct: 2325 -----IPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVD--GVPEPSIDWYRG 2377

Query: 2951 GKVLEQGSRFKLTSDF--GFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDN 3008
             +++    RF           TL + +    D+G YTC A N   E    + +    K+ 
Sbjct: 2378 EELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPKEI 2437

Query: 3009 LIERTQHPK 3017
              E  + P+
Sbjct: 2438 APEFQKEPE 2446



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 50/234 (21%), Positives = 93/234 (39%), Gaps = 15/234 (6%)

Query: 1057 EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG-----YVALDIASVRAE 1111
            EG    F+ RV  + +    VEW+ N + +  + +     D         +L I     E
Sbjct: 2218 EGDVVRFDIRVAGKPE--PVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEGCAPE 2275

Query: 1112 DSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEE 1171
            D  VY+VVA N AG+      + V ++   +  +           + E+    P  +   
Sbjct: 2276 DDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVPEEEAAS 2335

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
                 PVF++ + N   V EG+    +  ++ + +P+  ++W+     +    RF  + D
Sbjct: 2336 PETKAPVFIETMKN-IEVMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRF-VHID 2391

Query: 1232 F---GFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNE 1282
                    L I +    DTG+YT  A N +      A++  ++  +I  + Q E
Sbjct: 2392 AVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVL-TVKPKEIAPEFQKE 2444



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 68/291 (23%), Positives = 120/291 (41%), Gaps = 32/291 (10%)

Query: 1796 TSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQA--PRFITQLNGP 1853
            TSSTL + SK+ +  E  +   ++       +S     E++E   ++A  PRF+T L   
Sbjct: 1947 TSSTLAI-SKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPLKDQ 2005

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED 1913
             +L EG +   +  +E      + ++W+ + K L    R+  + D     + I  V  ED
Sbjct: 2006 -ELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTISPVTLED 2062

Query: 1914 SGEYTCKAINNL-GQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDS 1972
               Y      N+ G+AV+   + V+ KE+        + +  ++ + D +          
Sbjct: 2063 EAMYYKVVAENVAGEAVTDAEVIVEVKEA--------AEVTPVEEVVDAA---------- 2104

Query: 1973 FVVEKPQFGKPIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031
              V  P   KP+ +  +V EG  V LE  ++    P  +V WY +   +++  R     D
Sbjct: 2105 --VPAPIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLLEEDERIMYDTD 2160

Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082
                 L I  A  +D   Y C  TN  G     + + V+   G+ L  + E
Sbjct: 2161 GDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVE--EGISLPVIKE 2209



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 58/230 (25%), Positives = 84/230 (36%), Gaps = 26/230 (11%)

Query: 3683 EEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742
            EE+   + +  PPRF   +KD  ++ EG  V  D  VE  G   + I WF + +      
Sbjct: 1984 EELEAVESEAEPPRFVTPLKDQ-ELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDE 2040

Query: 3743 RVHTLNDFGFIALDIDYIYARD-AGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801
            R     D     + I  +   D A  Y   A N  G A T A++    K           
Sbjct: 2041 RHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK----------- 2089

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861
                 ++  +E   + DA    PI+  P           V E + VR EC +     P  
Sbjct: 2090 --EAAEVTPVE--EVVDAAVPAPIIIKPLN-----DEIDVLEGDSVRLECVI--SGGPDA 2138

Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            ++ WY++  LL    R     D    +L I     +D  EY C   N  G
Sbjct: 2139 QVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 35/148 (23%), Positives = 57/148 (38%), Gaps = 5/148 (3%)

Query: 45  TRQMTTQVESSGDRQPITAGRP---GEPSPP-IFEQIFKNARFAQGGNAKFEGKLRGNPT 100
           TR  +  +ES G     +  R    GE  P  + +   +  +    G  +   K+ G P 
Sbjct: 258 TRTFSVDIESEGPAPKESEKRKLLKGEERPKFVSDSTVEEFKITDEGELRLTVKVTGKPF 317

Query: 101 PVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVY 160
           P V WT+    L E ++  +   +  G V L IK +G  D G Y C   +  G +  S  
Sbjct: 318 PEVEWTKDDKDLKEDDRVIIS-EQDDGIVVLRIKDVGAHDSGVYKCQVSSDVGTSTKSFD 376

Query: 161 IQPEGXXXXXXXXXXXXXYRHVSETVEH 188
           +  EG               H+ + ++H
Sbjct: 377 VTIEGERRKAKKLIEVDETEHLEKRIKH 404



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 38/137 (27%), Positives = 64/137 (46%), Gaps = 9/137 (6%)

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
            DIV D + E   +        +  T+ + E+  +M  P   + L ++E  E      + R
Sbjct: 932  DIVIDDEAEYRCDIATDRGVVSMTTELIVEEAVLM--PVIIQPLKSLEIKEENAARFDVR 989

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS-----VYPEDSGVYTCQAT 1388
            ++  G     VEWF +G+ ++   RF    + D    +L S     V PED+G Y C A 
Sbjct: 990  VR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAV 1047

Query: 1389 NQLGEAVTSCALRVIAK 1405
            N+ G+A ++  L+V+ K
Sbjct: 1048 NEAGKATSTATLQVLTK 1064



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 7/92 (7%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG-----FIALDID 3758
            ++++ E     FD RV   G P   ++WF +GR      R   ++D         +L I+
Sbjct: 975  SLEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIE 1032

Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
             +   DAGEY C A N+ G AT+TA +    K
Sbjct: 1033 DVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 6/128 (4%)

Query: 1812 SQHESALQKIQQLEDSSRYQRRED---VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRI 1868
            S  ++   K     DS  + +  D   VE     AP FI  L    ++ E Q    EC +
Sbjct: 1127 SPSDAGTYKCVTKNDSGTFTQMFDITIVEKPEGAAPEFIKPLK-VLEVFETQPVRLECSV 1185

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
               P+P  ++ W   G V++   R  T  D     L+I     +D GEY C A+N+ G+A
Sbjct: 1186 TGTPEP--QITWLKGGDVVKEDDRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKA 1243

Query: 1929 VSSIRLNV 1936
             +   L V
Sbjct: 1244 ATVAELLV 1251



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 36/104 (34%), Positives = 48/104 (46%), Gaps = 6/104 (5%)

Query: 3684 EITIEDEKPN--PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            +ITI  EKP    P F   +K  ++V E  PV  +C V   G P  +I W   G      
Sbjct: 1150 DITIV-EKPEGAAPEFIKPLKV-LEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKED 1205

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             R+ T+ D     L+I      D GEY C A N +G A T A++
Sbjct: 1206 DRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAEL 1249



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 52/223 (23%), Positives = 92/223 (41%), Gaps = 26/223 (11%)

Query: 3954 TSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNG 4013
            ++EV + E +  +  + +PPRFVT ++ Q  L E  T   +  +   G   + ++WF + 
Sbjct: 1978 SAEVIVEELEAVE-SEAEPPRFVTPLKDQ-ELEEGSTV--DMLVETDGTSPIHIKWFKDN 2033

Query: 4014 KPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVY 4073
            K L+   R T   D     M    V  ED   Y                        +V 
Sbjct: 2034 KELVPDERHTFTKDGNKHTMTISPVTLEDEAMYY----------------------KVVA 2071

Query: 4074 DSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCR 4133
            ++   + +   E I E++ + +VTP + V ++    P +   L D + V EG+  R  C 
Sbjct: 2072 ENVAGEAVTDAEVIVEVKEAAEVTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRLECV 2131

Query: 4134 VTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYD 4176
            ++G P  +V+W  +   +    R     DG  H  I ++ + D
Sbjct: 2132 ISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELD 2174



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 80/316 (25%), Positives = 120/316 (37%), Gaps = 33/316 (10%)

Query: 3408 KDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
            K   + EE    PV    L + E   EG+   F+ R+    +P   VEW+ N + L    
Sbjct: 2193 KTELIVEEGISLPVIKEGLKDTE-ANEGDVVRFDIRVAGKPEP--VVEWFKNDELLDDSG 2249

Query: 3468 RFRTFCDFG-----FVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILES 3522
            +F    D          L I    PED   Y   A N  G+  +   + V  K     E 
Sbjct: 2250 KFIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKP----EQ 2305

Query: 3523 QLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNP----PEFTTTPSDLILSENSSAHFE 3578
            + P   +        LE    T+  + PE E+ +P    P F  T  ++ + E   A F+
Sbjct: 2306 EAPAQADAATP---ILEPLVETIPEV-PEEEAASPETKAPVFIETMKNIEVMEGEEARFD 2361

Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI--LEIGGVYQRDAGLYTCKATN 3636
              +  V + S  ++W+   + +    R   I+     I  L I      D G YTC A N
Sbjct: 2362 VHVDGVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAAN 2419

Query: 3637 RHGEATVSCKLQVKGRQ---GIILEPQLPSHFKSGTESIQKLEETLHKREEITIE---DE 3690
               E T    L VK ++       EP+  S F   T     L+ T+  +    +E   D+
Sbjct: 2420 DVDEITCEAVLTVKPKEIAPEFQKEPE-KSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDD 2478

Query: 3691 KP--NPPRFTVEIKDN 3704
            KP     R  V+ KD+
Sbjct: 2479 KPVKGTRRLEVKAKDD 2494



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 25/94 (26%), Positives = 43/94 (45%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            E   P+F +  KN    +G  A+F+  + G P P + W R +  + +  ++      +  
Sbjct: 2337 ETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEPSIDWYRGEELIPDEGRFVHIDAVKEE 2396

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
              +L+I+    GD G+YTC A N   E  C   +
Sbjct: 2397 IFTLVIENTKLGDTGKYTCIAANDVDEITCEAVL 2430



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 5/125 (4%)

Query: 45  TRQMTTQVESSGDRQPITAG---RPGEPSPP-IFEQIFKNARFAQGGNAKFEGKLRGNPT 100
           TR  +  +ES G     +     R GE  P  + +   +  +    G  +   K+ G P 
Sbjct: 632 TRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEEFKITDEGELRLTVKVTGKPF 691

Query: 101 PVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVY 160
           P V WT+    L E N+  +   +  G V L IK +G  D G Y C   +  G +  S  
Sbjct: 692 PEVEWTKDDKDLKEDNRVIIS-EQDDGIVVLRIKDVGAHDSGVYKCKVTSDVGTSTKSFD 750

Query: 161 IQPEG 165
           +  EG
Sbjct: 751 VTIEG 755



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 11/151 (7%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P++ +P+K+ E+ E     +    T    P   V+W+   +PV++  R     +    
Sbjct: 1460 EAPKYVEPLKSDEIVEDSSFTMNVKFT--GTPIPEVQWFKENKPVREDDRVHIIRESDSS 1517

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L I     +D G+Y    +N  G+AV+ + + V   S    +  DE  + K+       
Sbjct: 1518 TLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVS----EAEDEGIIPKVT-----P 1568

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDR 2126
             P   E   PGQ+P F      ++ LK+ +R
Sbjct: 1569 TPGKTEITIPGQKPKFGPVEVDIKGLKDKER 1599



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 57/226 (25%), Positives = 92/226 (40%), Gaps = 25/226 (11%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            + P F T LK  + L EG  V +  + +  T P + I+WFK+   L    R   T D   
Sbjct: 1994 EPPRFVTPLKDQE-LEEGSTVDMLVETDG-TSP-IHIKWFKDNKELVPDERHTFTKDGNK 2050

Query: 2700 VTLSINSLRNDDSGIY-TCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXX 2758
             T++I+ +  +D  +Y    A N+ GEAV+ A + +E +     E+     ++ +     
Sbjct: 2051 HTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK-----EAAEVTPVEEV----- 2100

Query: 2759 XXXXXXXXXXXXXXXXVFISHLNN-IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLP 2817
                            + I  LN+ I   EGD++  EC +  S  P  ++ W+ ++  L 
Sbjct: 2101 --------VDAAVPAPIIIKPLNDEIDVLEGDSVRLECVI--SGGPDAQVLWYKDDYLLE 2150

Query: 2818 SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
               R     D    +L I     +D   Y C  TN  GS      L
Sbjct: 2151 EDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL 2196



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 2/86 (2%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            + T P+     K   V E   V  EC+    ED   RI WY++   L    R+ T +D G
Sbjct: 867  IDTGPQIQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNG 924

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFG 3911
              SL I  +  +D  EY C    D G
Sbjct: 925  LCSLRIHDIVIDDEAEYRCDIATDRG 950



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 9/111 (8%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG--- 1099
            P  + PLK   +I E  +A F+ RV         VEW+ +G+Q+    R     D     
Sbjct: 967  PVIIQPLKSL-EIKEENAARFDVRVRGSPQ--PLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023

Query: 1100 --YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR-SSIDTSSIH 1147
                +L I  V  ED+G Y  VA N AG+A  +A++ V T+ S +D + +H
Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTKISELDKTPVH 1074



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 63/260 (24%), Positives = 101/260 (38%), Gaps = 19/260 (7%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E I E+    P     L+D  E  EG    F+ ++    +P   VEW+K+   +  S + 
Sbjct: 2195 ELIVEEGISLPVIKEGLKDT-EANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGKF 2251

Query: 820  TSIFNFG-----YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGI 874
              I +         SL I     ED   Y+V A+N+ G+  S   + V ++    A    
Sbjct: 2252 IIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEA---- 2307

Query: 875  PEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLE 934
            P Q                         PE T+ P F   +K+ I + EG  A F+  ++
Sbjct: 2308 PAQADAATPILEPLVETIPEVPEEEAASPE-TKAPVFIETMKN-IEVMEGEEARFDVHVD 2365

Query: 935  PIGDSTLRVEWLKDGRPVEASSRITTF--FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ 992
             + + +  ++W +    +    R             L I++  + D G YTC A N + +
Sbjct: 2366 GVPEPS--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDE 2423

Query: 993  ATTSANLTIVTKKDIIAESQ 1012
             T  A LT V  K+I  E Q
Sbjct: 2424 ITCEAVLT-VKPKEIAPEFQ 2442



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 90/431 (20%), Positives = 167/431 (38%), Gaps = 55/431 (12%)

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            V+    P+ ++ W  +GK +++    +L        L + +    DSG Y C   +  G+
Sbjct: 571  VKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGK 630

Query: 2995 AFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVF 3054
            +  + +V   SK    + ++  K  +G E+ + + DS  +E                  F
Sbjct: 631  STRTFSVDIESKGPATKESEKKKPRKGEERPKFVSDSTLEE------------------F 672

Query: 3055 KDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR-IRTVYAFGMVVLEILGT 3113
            K I D  EG++     ++  TG     +EW  + K ++  +R I +    G+VVL I   
Sbjct: 673  K-ITD--EGEL---RLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDV 726

Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLECV-DKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172
               DSG Y C+ T+  G +  S  +    ++ K +K            ++D   A FE T
Sbjct: 727  GAHDSGVYKCKVTSDVGTSTKSFDVTIEGERRKAKKLIEVDDTVAPHFVEDTSIAPFELT 786

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
                D  D+++     G+P  +    K   D  F      + +  D    + ++ +   +
Sbjct: 787  ----DSGDVRLSVRVAGKPEPNFKWTKDDEDIDFRSSQYTFERVDDRLTLIVKSPSPSDQ 842

Query: 3233 DFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVT 3292
               + T     KGG    + Q +       +E +    Q             I +     
Sbjct: 843  GTYKCTAT--NKGGTVTRTFQVN-------MEGIDTGPQ-------------IQEYSKEI 880

Query: 3293 KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENS 3352
            ++VEG S   E +    +  D ++ W+ +   L    R+ T  D G+  L I     ++ 
Sbjct: 881  EVVEGSSVTIECQSSGAE--DARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDE 938

Query: 3353 GEYEC-VATNK 3362
             EY C +AT++
Sbjct: 939  AEYRCDIATDR 949



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 7/104 (6%)

Query: 1304 DITVMQ-----APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR 1358
            DIT+++     AP+F + L  +E  E   V LEC +   G    ++ W   G  +K   R
Sbjct: 1150 DITIVEKPEGAAPEFIKPLKVLEVFETQPVRLECSV--TGTPEPQITWLKGGDVVKEDDR 1207

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                ++ +   L++     +D G Y C A N  G+A T   L V
Sbjct: 1208 ITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 3/102 (2%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            I E+  G  P F+  L  LE + E      EC V    +P +T  W   G  ++   R  
Sbjct: 1153 IVEKPEGAAPEFIKPLKVLE-VFETQPVRLECSVTGTPEPQIT--WLKGGDVVKEDDRIT 1209

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            T  D     L+I  +  +D G Y C A N  G+A     L V
Sbjct: 1210 TVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 56/241 (23%), Positives = 103/241 (42%), Gaps = 24/241 (9%)

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG-----FVSLD 3890
            +K     E + VRF+ RV  K +P   +EW++N +LL    ++  + D+        SL 
Sbjct: 2211 LKDTEANEGDVVRFDIRVAGKPEPV--VEWFKNDELLDDSGKFIIIDDVDDKDKELFSLV 2268

Query: 3891 ILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATI 3950
            I     ED   Y   A+N+ G+D +K  +     P    + + P    +++A T +   +
Sbjct: 2269 IEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKP----EQEAP---AQADAATPILEPL 2321

Query: 3951 KKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWF 4010
             +   EV   E++    + K P  F+ +      ++E E  +F+  +  V +P+  ++W+
Sbjct: 2322 VETIPEV--PEEEAASPETKAPV-FI-ETMKNIEVMEGEEARFDVHVDGVPEPS--IDWY 2375

Query: 4011 FNGKPLLHKNRFTPI--YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
               + +  + RF  I         +        D+G+Y C A N   +DE       T K
Sbjct: 2376 RGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAAN--DVDEITCEAVLTVK 2433

Query: 4069 P 4069
            P
Sbjct: 2434 P 2434



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            G+   P    + K  + +VEG  V +E Q     D   +I W+K+ V L    R ++ FD
Sbjct: 866  GIDTGPQIQEYSKEIE-VVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFD 922

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             GL +L I+ +  DD   Y C      G    T  + +E+
Sbjct: 923  NGLCSLRIHDIVIDDEAEYRCDIATDRGVVSMTTELIVEE 962



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 5/114 (4%)

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            RT QV  +  +   PQ       IE VEG++V +EC  Q  G +  R+ W+ +  P+   
Sbjct: 858  RTFQVNME-GIDTGPQIQEYSKEIEVVEGSSVTIEC--QSSGAEDARITWYKDDVPLGDS 914

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLIL 1410
             RF  A++    +L +  +  +D   Y C      G  V S    +I ++ +++
Sbjct: 915  PRFETAFDNGLCSLRIHDIVIDDEAEYRCDIATDRG--VVSMTTELIVEEAVLM 966



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            PEF  P+K  + + E      E  +   G    ++ WLK G  V+   RITT F+     
Sbjct: 1162 PEFIKPLK-VLEVFETQPVRLECSVT--GTPEPQITWLKGGDVVKEDDRITTVFDGETCV 1218

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I    + D G Y C A N  G+A T A L +
Sbjct: 1219 LNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 48/212 (22%), Positives = 85/212 (40%), Gaps = 38/212 (17%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            +++W+ ++KP+K   +          +L I+   P+D+  YTC+A N  G   T  I + 
Sbjct: 1393 EIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG-TTTRNINVD 1451

Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729
             S          EG  P         KY      DE++  +  FTM +K           
Sbjct: 1452 IS------ALMPEGEAP---------KYVEPLKSDEIVEDSS-FTMNVKF---------- 1485

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
                    G P   V+W +   P+   +R+  + +     L +    P+D G+Y     N
Sbjct: 1486 -------TGTPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSN 1538

Query: 1790 ELGEAVTSSTLFVQSKASLQLESQHESALQKI 1821
              G+AV+ + L V + +    E++ E  + K+
Sbjct: 1539 PFGKAVSEAELVVMTVS----EAEDEGIIPKV 1566



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 6/110 (5%)

Query: 1298 TKQVREDITVM----QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI 1353
            T+ +  DI+ +    +AP++   L + E VE ++  +  +    G     V+WF   KP+
Sbjct: 1445 TRNINVDISALMPEGEAPKYVEPLKSDEIVEDSSFTMNVKF--TGTPIPEVQWFKENKPV 1502

Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            +   R     E D   L +    P+D G Y    +N  G+AV+   L V+
Sbjct: 1503 REDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVM 1552



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 3/118 (2%)

Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468
            D S    +G+AP +  PL + E +   E++ F   +  T  P  +V+W+   K ++   R
Sbjct: 1451 DISALMPEGEAPKYVEPLKSDEIV---EDSSFTMNVKFTGTPIPEVQWFKENKPVREDDR 1507

Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPK 3526
                 +     L I+ T P+D G Y     N +G+AV+ A + V        E  +PK
Sbjct: 1508 VHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEAEDEGIIPK 1565



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            + P   +PL +  ++ EG +A  +C  +  G P   V W++++ L+E+  R++   D   
Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLEC--VISGGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
             ++ I     +DE  Y C  +N+ G
Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAG 1770



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 3/128 (2%)

Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750
            +P  PR T E+ D  +V E  PV         G+ +  + W  +       +RV    D 
Sbjct: 1890 EPAGPRITKELVD-AEVEETTPVTLVAEFVSEGETS--VTWTKDAHRVVADNRVTIKTDE 1946

Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810
                L I      D G YTC   NK G  +T+A++       +  E++ P+ ++  K +E
Sbjct: 1947 TSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPLKDQE 2006

Query: 3811 LERGRISD 3818
            LE G   D
Sbjct: 2007 LEEGSTVD 2014



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 54/242 (22%), Positives = 91/242 (37%), Gaps = 15/242 (6%)

Query: 2631 EMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR 2690
            E+ V+ G+   P+    LK  +   EG  V  + +V  + +P   +EWFKN   L    +
Sbjct: 2195 ELIVEEGIS-LPVIKEGLKDTEAN-EGDVVRFDIRVAGKPEP--VVEWFKNDELLDDSGK 2250

Query: 2691 LKSTFDFG-----LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESL 2745
                 D       L +L I     +D  +Y+  A N  G+  S   + +  +      + 
Sbjct: 2251 FIIIDDVDDKDKELFSLVIEGCAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQ 2310

Query: 2746 HPDSLDRIGALXXXXXXXXXXXXXX--XXXXVFISHLNNIVCKEGDNIHFECNVEPSRDP 2803
               +   +  L                    VFI  + NI   EG+   F+ +V+   +P
Sbjct: 2311 ADAATPILEPLVETIPEVPEEEAASPETKAPVFIETMKNIEVMEGEEARFDVHVDGVPEP 2370

Query: 2804 TLKIEWFFNNKPLPSGTRYKSTHDF--SYVSLDITHTYEEDSGIYTCKATNSKGSATTSG 2861
            +  I+W+   + +P   R+           +L I +T   D+G YTC A N     T   
Sbjct: 2371 S--IDWYRGEELIPDEGRFVHIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEA 2428

Query: 2862 SL 2863
             L
Sbjct: 2429 VL 2430



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 31/131 (23%), Positives = 62/131 (47%), Gaps = 7/131 (5%)

Query: 2608 DQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIF--TTHLKSYDKLVEGQHVYLEAQ 2665
            ++ + P   + ++ K     ++ E  VD  +++ P F  +  +K ++   EG  + + AQ
Sbjct: 411  EEQVMPTKVKPVETKVDKPRQIEE--VDAMLKEEPTFLESDEIKPFEVTEEGD-IKMTAQ 467

Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            V  +  P+  +EWFK+ V ++    +  T + G  +L I      D G YT + +N  G 
Sbjct: 468  VTGKPQPS--VEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGL 525

Query: 2726 AVSTASIKIED 2736
               T  + ++D
Sbjct: 526  GRRTFDVSVDD 536



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 49/199 (24%), Positives = 76/199 (38%), Gaps = 19/199 (9%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  ++ W K+G  +     ++         L+I     DDSG Y C  T+ +G++  T S
Sbjct: 577  PEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFS 636

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            + IE +     ES       R G                     F+S       K  D  
Sbjct: 637  VDIESKGPATKES--EKKKPRKGE----------------ERPKFVSDSTLEEFKITDEG 678

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLDITHTYEEDSGIYTCKA 2850
                 V+ +  P  ++EW  ++K L    R   S  D   V L I      DSG+Y CK 
Sbjct: 679  ELRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKV 738

Query: 2851 TNSKGSATTSGSLRCTGDK 2869
            T+  G++T S  +   G++
Sbjct: 739  TSDVGTSTKSFDVTIEGER 757



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 90/411 (21%), Positives = 152/411 (36%), Gaps = 63/411 (15%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I G    D   YS  A N+ G+     KL    + K ++P      +  + L D +  
Sbjct: 1847 LVIEGCAPDDDAVYSVVAMNEAGKDTSKGKLLVHSRPKQEQPTEPAGPRITKELVDAEVE 1906

Query: 3168 HFE-CTVVP--VDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
                 T+V   V + +  + W  +   +    R+   +D     L I+ +   D G Y C
Sbjct: 1907 ETTPVTLVAEFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTC 1966

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKF 3284
               NK G+  T A +                    + ELE+++           AEPP+F
Sbjct: 1967 TVRNKMGDTSTSAEV-------------------IVEELEAVES---------EAEPPRF 1998

Query: 3285 ITQIQDVTKLVEGQSAHFEARLVPVDDPD-LKVEWFYNGKKLPHGHRYRTFHDFGIVILD 3343
            +T ++D  +L EG +      LV  D    + ++WF + K+L    R+    D     + 
Sbjct: 1999 VTPLKD-QELEEGSTVDM---LVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMT 2054

Query: 3344 IL-YCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLED 3402
            I     E+ +  Y+ VA N  G   T A +    KE               +  ++ + D
Sbjct: 2055 ISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKE------------AAEVTPVEEVVD 2102

Query: 3403 SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKS 3462
            + V             AP+   PL++  ++ EG++   E  +  +  P+ +V WY +   
Sbjct: 2103 AAV------------PAPIIIKPLNDEIDVLEGDSVRLECVI--SGGPDAQVLWYKDDYL 2148

Query: 3463 LKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            L+   R     D     L I     +D  EY C   N  G       + V+
Sbjct: 2149 LEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVE 2199



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 2/84 (2%)

Query: 781  ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
            ++ +G +   E ++T   +P   ++W+KD +P+  S +I   +     SL I+    +D 
Sbjct: 1373 KISDGGDLTLEVKIT--GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDT 1430

Query: 841  GSYTVRAVNKLGEAISTASIRVAA 864
              YT +A NK G      ++ ++A
Sbjct: 1431 AKYTCKATNKSGTTTRNINVDISA 1454



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 75/308 (24%), Positives = 110/308 (35%), Gaps = 25/308 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG---- 3130
            TG     ++WF   K +    R+  +       L I  T   D G+Y    +N +G    
Sbjct: 1486 TGTPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVS 1545

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ 3190
            +AE+ V      + +G  P+ T      E    GQ   F    V VD   +K +     +
Sbjct: 1546 EAELVVMTVSEAEDEGIIPKVTPTPGKTEITIPGQKPKFG--PVEVDIKGLKDK---ERE 1600

Query: 3191 PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINC-YGKGGVYL 3249
             +     I     FG V + I      D    V  A       F    I+   G    ++
Sbjct: 1601 RLTSEASIAGRKPFGAVDMSIT-APGEDKKPTVTEA-EFTPVAFKPVEISVPIGDEAPFI 1658

Query: 3250 E---SLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARL 3306
                + +PD     + LE +         TP+ E P  I  + D   ++EG SA  E   
Sbjct: 1659 SLKGAKKPDLPVLAKPLEVIMPVS----FTPAEEAPFIIKPLNDEIDVLEGDSARLEC-- 1712

Query: 3307 VPVDDPDLKVEWFYNGKKLPHGHR--YRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            V    PD  V W+ +   L    R  Y T  D   +I+      +E   EY+CV TN  G
Sbjct: 1713 VISGGPDAHVFWYKDDYLLEEDERVSYETDGDQHTLIIQSAELDDE--AEYKCVVTNIAG 1770

Query: 3365 RDSTKANL 3372
                K  L
Sbjct: 1771 SVDVKTEL 1778



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 2/105 (1%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            E + +    V W KD   V A +R+T   +     L I    V D G YTC   N +G  
Sbjct: 1916 EFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDT 1975

Query: 994  TTSANLTIVTKKDIIAESQHPGGLE--KIQYLEDASRYSKRTEEE 1036
            +TSA + +   + + +E++ P  +   K Q LE+ S      E +
Sbjct: 1976 STSAEVIVEELEAVESEAEPPRFVTPLKDQELEEGSTVDMLVETD 2020



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 8/89 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI-----TKTHD 2430
            PV  QPL++++ I+E   A FD R+   G P   VEWF++ + ++D  R          D
Sbjct: 967  PVIIQPLKSLE-IKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
                S+ I  V  ED G Y C A N  G+
Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAGK 1052



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 3/103 (2%)

Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228
            +E+   + P F++PL     V E + + LEC +   G P  ++ W   G  V    R  T
Sbjct: 1154 VEKPEGAAPEFIKPLK-VLEVFETQPVRLECSVT--GTPEPQITWLKGGDVVKEDDRITT 1210

Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
             +D     L+I  +   D GEY   A+N  G A T A + V E
Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLVNE 1253



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 65/267 (24%), Positives = 107/267 (40%), Gaps = 30/267 (11%)

Query: 2904 PDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLT 2963
            P T+   P    P   E  L       L  +V+   +P  +I+W+ + K ++   + ++ 
Sbjct: 1353 PITDVGTPPEFSPHVGEGPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVD 1412

Query: 2964 SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLE 3023
                  +L +V     D+  YTCKA NK G    +  V  ++   L+   + PK  E L+
Sbjct: 1413 YRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISA---LMPEGEAPKYVEPLK 1469

Query: 3024 KIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIE 3083
              + +EDS            TG P      FK+   + E    H    +I   D S ++ 
Sbjct: 1470 SDEIVEDS----SFTMNVKFTGTPIPEVQWFKENKPVREDDRVH----IIRESDSSTLV- 1520

Query: 3084 WFYNGKTI---EASHRIRTVYAFGMVVLE----ILGTKTTDSGTYSCRATNKWGQAEISV 3136
                 KT+   E S++I     FG  V E    ++     +      + T   G+ EI++
Sbjct: 1521 ---ITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEAEDEGIIPKVTPTPGKTEITI 1577

Query: 3137 KLECVDKSKGQKPRFTTHIQNIEGLKD 3163
                     GQKP+F     +I+GLKD
Sbjct: 1578 --------PGQKPKFGPVEVDIKGLKD 1596



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 54/219 (24%), Positives = 87/219 (39%), Gaps = 29/219 (13%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F++ L +   +EG  +  +  VE      + I+WF +NK L    R+  T D +  ++ I
Sbjct: 1998 FVTPLKDQELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHTMTI 2055

Query: 2836 TH-TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            +  T E+++  Y   A N  G A T   +                    +E  E AE   
Sbjct: 2056 SPVTLEDEAMYYKVVAENVAGEAVTDAEVI-------------------VEVKEAAEVTP 2096

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
            + +     V D   P P  I P+  E  ++EG  + LE  +     PD ++ WY +  +L
Sbjct: 2097 VEE-----VVDAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLL 2149

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            E+  R    +D    TL +      D   Y C   N  G
Sbjct: 2150 EEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F   LK  + + E Q V LE  V    +P  +I W K G  +    R+ + FD    
Sbjct: 1161 APEFIKPLKVLE-VFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITTVFDGETC 1217

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             L+I     DD G Y C A N  G+A + A + + +
Sbjct: 1218 VLNITVSCLDDEGEYKCLAMNDFGKAATVAELLVNE 1253



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 28/121 (23%), Positives = 58/121 (47%), Gaps = 4/121 (3%)

Query: 636  PPQFI--VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
            PP+F   V    +   +GG +  E +I   G+P  +I+W K+ + ++ S +    +R   
Sbjct: 1360 PPEFSPHVGEGPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPVKPSQKIRVDYRDDI 1417

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753
             SL ++  +  D+ +YTC+A + +G       + ++         ++ E L+  + +ED 
Sbjct: 1418 HSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALMPEGEAPKYVEPLKSDEIVEDS 1477

Query: 754  S 754
            S
Sbjct: 1478 S 1478



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/83 (28%), Positives = 39/83 (46%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F  H+     K  D       V+ + +P  +I+WF ++KP+    + +  +     SL I
Sbjct: 1363 FSPHVGEGPLKISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTI 1422

Query: 2836 THTYEEDSGIYTCKATNSKGSAT 2858
                 +D+  YTCKATN  G+ T
Sbjct: 1423 VGASPDDTAKYTCKATNKSGTTT 1445



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 48/227 (21%), Positives = 87/227 (38%), Gaps = 12/227 (5%)

Query: 2518 SELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG-----FVTLDINS 2572
            +E  EG    ++ RV   G P    EW+ N   L    +F    D         +L I  
Sbjct: 2214 TEANEGDVVRFDIRVA--GKPEPVVEWFKNDELLDDSGKFIIIDDVDDKDKELFSLVIEG 2271

Query: 2573 VVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEM 2632
                D  +Y   A+N AG                   A    +   ++     + +VPE 
Sbjct: 2272 CAPEDDAVYSVVAMNEAGKDSSKGKLLVNSKPEQEAPAQADAATPILEPLVETIPEVPEE 2331

Query: 2633 FVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK 2692
               +   +AP+F   +K+ + ++EG+    +  V+   +P+  I+W++    +    R  
Sbjct: 2332 EAASPETKAPVFIETMKNIE-VMEGEEARFDVHVDGVPEPS--IDWYRGEELIPDEGRFV 2388

Query: 2693 --STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
                    + TL I + +  D+G YTC A N + E    A + ++ +
Sbjct: 2389 HIDAVKEEIFTLVIENTKLGDTGKYTCIAANDVDEITCEAVLTVKPK 2435



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P    P+FI  ++ V ++ E Q    E  +    +P  ++ W   G  +    R  T  D
Sbjct: 1157 PEGAAPEFIKPLK-VLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITTVFD 1213

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
                +L+I     ++ GEY+C+A N  G+ +T A L
Sbjct: 1214 GETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAEL 1249



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 65/302 (21%), Positives = 108/302 (35%), Gaps = 28/302 (9%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     +EW  +   +     I          L I      D GTY+   +N+ G    
Sbjct: 95   TGKPQPSVEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRR 154

Query: 3135 SVKLECVDKSK-----GQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189
            +  +   D  K       KP+F      +   +         TV     P+ ++ W  +G
Sbjct: 155  TFDVSVDDTRKTIPKDAVKPKFIEDGSFVP-FQSTDEGDVRLTVKVTGKPEPEVTWTKDG 213

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYL 3249
            +P+     ++        +L I      DSG Y C   +  G+     +++   +G    
Sbjct: 214  KPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKSTRTFSVDIESEGPAPK 273

Query: 3250 ESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPV 3309
            ES       + R+L  L+G           E PKF++    V +            +   
Sbjct: 274  ES-------EKRKL--LKG----------EERPKFVSD-STVEEFKITDEGELRLTVKVT 313

Query: 3310 DDPDLKVEWFYNGKKLPHGHR-YRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDST 3368
              P  +VEW  + K L    R   +  D GIV+L I      +SG Y+C  ++ +G  ST
Sbjct: 314  GKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVSSDVG-TST 372

Query: 3369 KA 3370
            K+
Sbjct: 373  KS 374



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 42/146 (28%), Positives = 63/146 (43%), Gaps = 10/146 (6%)

Query: 3567 LILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG-----FVILEIGG 3621
            L + E ++A F+ R+         VEWF +G+ L    R   I+D          L I  
Sbjct: 976  LEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIED 1033

Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHK 3681
            V   DAG Y C A N  G+AT +  LQV  +  I    + P H   G++   K+  +   
Sbjct: 1034 VIPEDAGEYECVAVNEAGKATSTATLQVLTK--ISELDKTPVHTVEGSDITMKVAVSGTP 1091

Query: 3682 REEIT-IEDEKPNPPRFTVEIKDNID 3706
            R E+   +D++    R    IK  +D
Sbjct: 1092 RTEVEWYKDDRKLSNRKPYVIKTTVD 1117



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 3/109 (2%)

Query: 768  QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827
            + P+++ PL+   E+ E  +     + T    P   V+W+K+ +P+    R+  I     
Sbjct: 1460 EAPKYVEPLKS-DEIVEDSSFTMNVKFT--GTPIPEVQWFKENKPVREDDRVHIIRESDS 1516

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPE 876
             +L I     +D GSY +   N  G+A+S A + V   S    +  IP+
Sbjct: 1517 STLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEAEDEGIIPK 1565



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 66/285 (23%), Positives = 103/285 (36%), Gaps = 34/285 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSS-MRVEWFHNGKPLLTG 3603
            V+ L        PP F T   D  L E S+      L+  + +S + ++WF + K L+  
Sbjct: 1983 VEELEAVESEAEPPRFVTPLKDQELEEGSTVDM---LVETDGTSPIHIKWFKDNKELVPD 2039

Query: 3604 SRVKTINDFGFVILEIGGVYQRDAGLY-TCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662
             R     D     + I  V   D  +Y    A N  GEA    ++ V+ ++   + P   
Sbjct: 2040 ERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKEAAEVTP--- 2096

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
                        +EE +         D     P     + D IDV EG  V  +C +   
Sbjct: 2097 ------------VEEVV---------DAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS-- 2133

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G P  ++ W+ +        R+    D     L I      D  EY C  TN  GS    
Sbjct: 2134 GGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVK 2193

Query: 3783 AKITCSAKRDI-VLESQLPQGMSGEKIKELERGRISDAPKEEPIV 3826
             ++       + V++  L    + E   ++ R  I  A K EP+V
Sbjct: 2194 TELIVEEGISLPVIKEGLKDTEANE--GDVVRFDIRVAGKPEPVV 2236



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/117 (25%), Positives = 55/117 (47%), Gaps = 6/117 (5%)

Query: 2622 KEAAMNKVPEMFVDTGVQQAPIF--TTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWF 2679
            K A + ++PE  VD  +++ P F  +  +K ++   EG  + L  QV  +  P+  +EW 
Sbjct: 50   KLACLQRIPEE-VDAMLKEEPTFLESDEIKPFEVTEEGD-IKLTVQVTGKPQPS--VEWL 105

Query: 2680 KNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            K+ V ++    +  T +    +L I      D G YT + +N  G    T  + ++D
Sbjct: 106  KDDVPVSPDEHITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDD 162



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 2/93 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            PQ  +  K  EV EG  V +E   +   D   R+ WY +  P+    RF+T +D G  +L
Sbjct: 871  PQIQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSL 928

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             I     +D   Y C      G    T+ + V+
Sbjct: 929  RIHDIVIDDEAEYRCDIATDRGVVSMTTELIVE 961



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 5/84 (5%)

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFG-----FVTLDLVDVYERDSGIYTCKAY 2989
            V  +  P   +EW+ +G+ L+   RF +  D         +L + DV   D+G Y C A 
Sbjct: 988  VRVRGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAV 1047

Query: 2990 NKRGEAFTSSTVYCTSKDNLIERT 3013
            N+ G+A +++T+   +K + +++T
Sbjct: 1048 NEAGKATSTATLQVLTKISELDKT 1071



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 72/352 (20%), Positives = 127/352 (36%), Gaps = 66/352 (18%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            +P F+      E +  G+   F  + E    P   +DW+H    +    R+    +    
Sbjct: 1257 KPKFIETTHDTEIIT-GESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRFLINTEEDTS 1313

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQG 2227
             L I      D G Y C  +N  GE +    L V   +  I D   P             
Sbjct: 1314 TLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTP------------- 1360

Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287
                     P+ SP   V E  G   + +G     E ++    +P   I+++ + K ++ 
Sbjct: 1361 ---------PEFSP--HVGE--GPLKISDGGDLTLEVKI--TGEPKPEIQWFKDDKPVKP 1405

Query: 2288 AARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
            + +  + +     SL I    P+D  +Y+ KA N  G        T T   ++   +  P
Sbjct: 1406 SQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSG--------TTTRNINVDISALMP 1457

Query: 2348 EGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPT 2407
            EG                        + P + +PL++ D I E  +   + +    G P 
Sbjct: 1458 EG------------------------EAPKYVEPLKS-DEIVEDSSFTMNVKF--TGTPI 1490

Query: 2408 LKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             +V+WF+  K + +  R+    +    ++ I+    +DEG Y    SN  G+
Sbjct: 1491 PEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGK 1542



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 4/81 (4%)

Query: 87  GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146
           G+ +   K+ G P P V+WT+   P+ +     + + E      L I++  P D G Y C
Sbjct: 191 GDVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDR--YILTIREASPDDSGSYRC 248

Query: 147 TARNQYGEA--ICSVYIQPEG 165
           T  +  G++    SV I+ EG
Sbjct: 249 TLTSDVGKSTRTFSVDIESEG 269



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 38/149 (25%), Positives = 62/149 (41%), Gaps = 13/149 (8%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            PQ     K +  +EG  +  E +     D   +I W K+   +  S RF + F  G  SL
Sbjct: 871  PQIQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSL 928

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
             +  + I D  EY C       +A  + V+ +T    +E     P  +Q ++ LE   + 
Sbjct: 929  RIHDIVIDDEAEYRC------DIATDRGVVSMTTELIVEEAVLMPVIIQPLKSLEIKEEN 982

Query: 757  QHQESIEEQTSQRP-----QFIRPLQDLG 780
              +  +  + S +P     +  R LQDLG
Sbjct: 983  AARFDVRVRGSPQPLVEWFKDGRQLQDLG 1011



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 7/100 (7%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG---- 2033
            P   +P+K+ E+ E +    +  +     P   VEW+ +GR +Q   RF    D      
Sbjct: 967  PVIIQPLKSLEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDK 1024

Query: 2034 -YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
               +L I     ED G Y C A N  G+A +T++++V  K
Sbjct: 1025 ELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 2/101 (1%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP  I  LN    + EG SA  EC I   PD +  V WY +  +L+   R     D   
Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLECVISGGPDAH--VFWYKDDYLLEEDERVSYETDGDQ 1745

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
              L I +   +D  EY C   N  G       L V+   S+
Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISL 1786



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 47/217 (21%), Positives = 83/217 (38%), Gaps = 23/217 (10%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            PP+F+ PLK     EG  +  +  +E  G   + I+W K+ + +    R T        +
Sbjct: 1995 PPRFVTPLKDQELEEGSTV--DMLVETDGTSPIHIKWFKDNKELVPDERHTFTKDGNKHT 2052

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            + +  + ++D   Y         VAE  A   VT               + I ++++ ++
Sbjct: 2053 MTISPVTLEDEAMYY------KVVAENVAGEAVTDA-------------EVIVEVKEAAE 2093

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                E + +     P  I+PL D  ++ EG +   E  ++    P  +V WYKD   +  
Sbjct: 2094 VTPVEEVVDAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKDDYLLEE 2151

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852
              RI    +    +L I     +D   Y     N  G
Sbjct: 2152 DERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 33/125 (26%), Positives = 47/125 (37%), Gaps = 5/125 (4%)

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
            E    I+V EG  V  +C+     D   RI W+ +  P     R  T  D G  +L I  
Sbjct: 875  EYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHD 932

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
            I   D  EY C      G  + T ++      + VL   + Q +   +IKE    R    
Sbjct: 933  IVIDDEAEYRCDIATDRGVVSMTTELIV---EEAVLMPVIIQPLKSLEIKEENAARFDVR 989

Query: 3820 PKEEP 3824
             +  P
Sbjct: 990  VRGSP 994



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 28/114 (24%), Positives = 49/114 (42%), Gaps = 5/114 (4%)

Query: 3950 IKKYTSEVYLTEDDLYDVDKKQ--PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKV 4007
            + K  S  +    D+  V+K +   P F+  ++    + E +  + EC +   G P  ++
Sbjct: 1137 VTKNDSGTFTQMFDITIVEKPEGAAPEFIKPLKV-LEVFETQPVRLECSVT--GTPEPQI 1193

Query: 4008 EWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
             W   G  +   +R T ++D     +N      +D GEY C A N +G   T A
Sbjct: 1194 TWLKGGDVVKEDDRITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVA 1247



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 3/101 (2%)

Query: 2234 VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI 2293
            VE+P+ + P F+  L+    VFE +    EC V    +P  +I +   G  ++   R   
Sbjct: 1154 VEKPEGAAPEFIKPLK-VLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITT 1210

Query: 2294 TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             FD     L+I     +D GEY   A+N  G   +   + V
Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 8/119 (6%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            +PE  + P++  P+K    +++  F      ++  G     V+W K+ +PV    R+   
Sbjct: 1456 MPEG-EAPKYVEPLKSDEIVEDSSFT---MNVKFTGTPIPEVQWFKENKPVREDDRVHII 1511

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020
                   L I      D G Y     N  G+A + A L ++T    ++E++  G + K+
Sbjct: 1512 RESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMT----VSEAEDEGIIPKV 1566



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 7/95 (7%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-----STHDFS 2829
            V I  L ++  KE +   F+  V  S  P   +EWF + + L    R+         D  
Sbjct: 968  VIIQPLKSLEIKEENAARFDVRVRGSPQPL--VEWFKDGRQLQDLGRFMIIDDVDDQDKE 1025

Query: 2830 YVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
              SL I     ED+G Y C A N  G AT++ +L+
Sbjct: 1026 LYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQ 1060



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 3/106 (2%)

Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100
            + P+++ PLK +++IVE  S  F   V+        V+W+   K +   +R+    +   
Sbjct: 1460 EAPKYVEPLK-SDEIVEDSS--FTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDS 1516

Query: 1101 VALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSI 1146
              L I     +D G Y +V  N  G+A   A + V T S  +   I
Sbjct: 1517 STLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVSEAEDEGI 1562



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 2/82 (2%)

Query: 491 PKFVE--RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
           P F+E        V E   + L  +  G P P + W KD VP+ P+  + I  +    +L
Sbjct: 69  PTFLESDEIKPFEVTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHITITEEDDTYSL 128

Query: 549 DIPRAKASDAAWYQCTAQNVAG 570
            I      D   Y     N AG
Sbjct: 129 VIKEPTKKDEGTYTVEVSNEAG 150



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 9/121 (7%)

Query: 2619 IQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEW 2678
            I      ++   E+ V+  V   P+    LKS +   E    +    V  R  P   +EW
Sbjct: 945  IATDRGVVSMTTELIVEEAVLM-PVIIQPLKSLEIKEENAARF---DVRVRGSPQPLVEW 1000

Query: 2679 FKNGVTLTTGARLKSTFDFG-----LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733
            FK+G  L    R     D       L +L I  +  +D+G Y C A N  G+A STA+++
Sbjct: 1001 FKDGRQLQDLGRFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQ 1060

Query: 2734 I 2734
            +
Sbjct: 1061 V 1061



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 8/101 (7%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG--- 1233
            PV +QPL +   + E      + R+   G P   VEWF +GR +    RF    D     
Sbjct: 967  PVIIQPLKSLE-IKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023

Query: 1234 --FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
                +L I      D GEY   AVN  G A ++A ++V+ +
Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 31/98 (31%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PKFI       +   E V F  + E    P   ++WY    L+    R+    +    +L
Sbjct: 1258 PKFIETTHDTEIITGESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRFLINTEEDTSTL 1315

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFT--KATISCKKLP 3925
             I  V   D G Y C   ND GED T  K T+  KK P
Sbjct: 1316 IIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKP 1353



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 25/83 (30%), Positives = 36/83 (43%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+F +          T   +   L   G  T +VEWF + KP+K   R     + D  +
Sbjct: 2438 APEFQKEPEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHS 2497

Query: 1370 LDLLSVYPEDSGVYTCQATNQLG 1392
            L +    P+DSG YT  A +  G
Sbjct: 2498 LKIKGGKPDDSGKYTVVAESPAG 2520



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 21/59 (35%), Positives = 31/59 (52%)

Query: 794  LTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852
            LT    PT +VEW+KD +P+  + R+         SL I   + +D+G YTV A +  G
Sbjct: 2462 LTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAG 2520



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 29/113 (25%), Positives = 50/113 (44%), Gaps = 6/113 (5%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            +AP     LK+ EI E   + F   +        +V+W+  NKP++   R          
Sbjct: 1460 EAPKYVEPLKSDEIVED--SSFTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDSS 1517

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRL 1688
             L I   +P+D G+Y     N  G+AV+    +V +      E++ EG +P++
Sbjct: 1518 TLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMTVS----EAEDEGIIPKV 1566



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 909  PEF-KTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            PEF K P K    +  G     +  L   G  T +VEW KD +PV+ + R+         
Sbjct: 2439 PEFQKEPEKSTFDVNTGDDVSLD--LTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEH 2496

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQAT 994
            +L IK     D+G YT  A +  G+ T
Sbjct: 2497 SLKIKGGKPDDSGKYTVVAESPAGRDT 2523



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 33/140 (23%), Positives = 54/140 (38%), Gaps = 8/140 (5%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            E I   P      K+I V E  +   E +    G    R+ W ++ VP+  S R  T  D
Sbjct: 865  EGIDTGPQIQEYSKEIEVVEGSSVTIECQ--SSGAEDARITWYKDDVPLGDSPRFETAFD 922

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824
             G  +L +  +  +D   Y C    + G    ++ L V+    + +       +Q ++ L
Sbjct: 923  NGLCSLRIHDIVIDDEAEYRCDIATDRGVVSMTTELIVEEAVLMPV------IIQPLKSL 976

Query: 1825 EDSSRYQRREDVEVAVNQAP 1844
            E       R DV V  +  P
Sbjct: 977  EIKEENAARFDVRVRGSPQP 996



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 36/121 (29%), Positives = 48/121 (39%), Gaps = 5/121 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G     VEW KD R +                LTI S +  DAG Y C   N  G  T  
Sbjct: 1089 GTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYKCVTKNDSGTFTQM 1148

Query: 997  ANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIV 1056
             ++TIV K     E   P  ++ ++ LE       R E  V  T +P+    LKG + + 
Sbjct: 1149 FDITIVEK----PEGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEPQITW-LKGGDVVK 1203

Query: 1057 E 1057
            E
Sbjct: 1204 E 1204



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 2/101 (1%)

Query: 2636 TGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF 2695
            T  ++AP     L     ++EG    LE  +     P+  + W+K+   L    R+    
Sbjct: 1684 TPAEEAPFIIKPLNDEIDVLEGDSARLECVISG--GPDAHVFWYKDDYLLEEDERVSYET 1741

Query: 2696 DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            D    TL I S   DD   Y C  TN+ G       + +E+
Sbjct: 1742 DGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEE 1782



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 28/118 (23%), Positives = 45/118 (38%), Gaps = 2/118 (1%)

Query: 760 ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
           E ++    + P F+    ++   +       +  +     P   VEW KD  P++    I
Sbjct: 59  EEVDAMLKEEPTFLES-DEIKPFEVTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHI 117

Query: 820 TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV-AARSTVTADLGIPE 876
           T        SL I     +D G+YTV   N+ G    T  + V   R T+  D   P+
Sbjct: 118 TITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPK 175



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGAR-LKSTFDFGLVTLSINSLRNDDSGIYTCKAT 2720
            L   V+    P  ++EW K+   L    R + S  D G+V L I  +   DSG+Y CK T
Sbjct: 680  LRLTVKVTGKPFPEVEWTKDDKDLKEDNRVIISEQDDGIVVLRIKDVGAHDSGVYKCKVT 739

Query: 2721 NLLGEAVSTASIKIE 2735
            + +G +  +  + IE
Sbjct: 740  SDVGTSTKSFDVTIE 754



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 61/286 (21%), Positives = 108/286 (37%), Gaps = 43/286 (15%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E+  KP+F     D   I  G    F  + E  G  T  V+W  +   V  + R    
Sbjct: 1251 VNEALVKPKFIETTHDT-EIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRFLIN 1307

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
                   L I+ V   D G+Y C   N  G+  T + LT++ KK  I +   P       
Sbjct: 1308 TEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTP------- 1360

Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARV--EPQSDLTMTVEW 1079
                   +S    E           GPL    KI +G     E ++  EP+ +    ++W
Sbjct: 1361 -----PEFSPHVGE-----------GPL----KISDGGDLTLEVKITGEPKPE----IQW 1396

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139
            + + K +  + +I+  +     +L I     +D+  YT  A N +G    + ++ +    
Sbjct: 1397 FKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISALM 1456

Query: 1140 SIDTSSIHRGLYEKTRHIEESKFV-------EPMYQIEEISKSKPV 1178
                +  +    +    +E+S F         P+ +++   ++KPV
Sbjct: 1457 PEGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQWFKENKPV 1502



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 2/89 (2%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            E   P + +  K+    +  +     K  G P P V W ++  P+ E ++  +    ++ 
Sbjct: 1458 EGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQWFKENKPVREDDR--VHIIRESD 1515

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
              +L+I +  P DEG Y     N +G+A+
Sbjct: 1516 SSTLVITKTVPDDEGSYKIVLSNPFGKAV 1544



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 61/293 (20%), Positives = 103/293 (35%), Gaps = 23/293 (7%)

Query: 2939 NDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            ++ +  + W  +   +   +R  + +D    TL +      D G+YTC   NK G+  TS
Sbjct: 1919 SEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTS 1978

Query: 2999 STVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIV 3058
            + V     + +    + P+    L K Q LE+    +   + D   G  P     FKD  
Sbjct: 1979 AEVIVEELEAVESEAEPPRFVTPL-KDQELEEGSTVDMLVETD---GTSPIHIKWFKD-- 2032

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
                         L+P    +   +   +  TI           + +V   + G   TD+
Sbjct: 2033 ----------NKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDA 2082

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
                         AE++   E VD +    P     + +   + +G S   EC +     
Sbjct: 2083 EV----IVEVKEAAEVTPVEEVVDAAV-PAPIIIKPLNDEIDVLEGDSVRLECVI--SGG 2135

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            PD ++ WY +   +    RI   +D     L I   +  D  EY C   N  G
Sbjct: 2136 PDAQVLWYKDDYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG 2188



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 1435 IIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494
            I+++     P F+ +P  +  V E Q V  EC +    +   ++ W K G  V    R  
Sbjct: 1153 IVEKPEGAAPEFI-KPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRIT 1209

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
             + D     L+I     +D G Y C A+N  G
Sbjct: 1210 TVFDGETCVLNITVSCLDDEGEYKCLAMNDFG 1241



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 12/115 (10%)

Query: 1690 QLEDTSKYQRHSAQD-EVITQAPVFTMPMKDIRVA---ENQAAHFEAR--------LIPV 1737
            +L DT KY   +A D + IT   V T+  K+I      E + + F+          L   
Sbjct: 2406 KLGDTGKYTCIAANDVDEITCEAVLTVKPKEIAPEFQKEPEKSTFDVNTGDDVSLDLTVT 2465

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G P  +VEW ++  P++ + RL         +L +K   P+DSG YT  A +  G
Sbjct: 2466 GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAG 2520



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 8/113 (7%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            +T E +VEE  A   PV +    ++ ++E   ARF  RV G P+P V W  +G  + +  
Sbjct: 954  MTTELIVEE--AVLMPVIIQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLG 1011

Query: 4156 RYKLTYD------GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
            R+ +  D       +Y   I      D G+ E +             L+V+ +
Sbjct: 1012 RFMIIDDVDDQDKELYSLVIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 1/63 (1%)

Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            +VE+ +   P  F+     + V E +  R  C VTG P+P++ WL  G+ +    R    
Sbjct: 1153 IVEKPEGAAPE-FIKPLKVLEVFETQPVRLECSVTGTPEPQITWLKGGDVVKEDDRITTV 1211

Query: 4161 YDG 4163
            +DG
Sbjct: 1212 FDG 1214



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 21/71 (29%), Positives = 32/71 (45%)

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852
            F  NV+ +  P  +++WF  NKP+    R     +    +L IT T  +D G Y    +N
Sbjct: 1479 FTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSN 1538

Query: 2853 SKGSATTSGSL 2863
              G A +   L
Sbjct: 1539 PFGKAVSEAEL 1549



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 5/120 (4%)

Query: 758  HQESIEEQTSQR--PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
            H    +EQ ++   P+  + L D  E++E       A+   VS+    V W KD   + A
Sbjct: 1880 HSRPKQEQPTEPAGPRITKELVD-AEVEETTPVTLVAEF--VSEGETSVTWTKDAHRVVA 1936

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
             +R+T   +    +L I     +D G YT    NK+G+  ++A + V     V ++   P
Sbjct: 1937 DNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPP 1996



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 36/142 (25%), Positives = 59/142 (41%), Gaps = 7/142 (4%)

Query: 3511 KVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVD-TLTPEAES-GNPPEFTTTPSDLI 3568
            +V  +  +I++S  P   +GT    A  +G  GTV  T     E     P+      ++ 
Sbjct: 825  RVDDRLTLIVKSPSPSD-QGTYKCTATNKG--GTVTRTFQVNMEGIDTGPQIQEYSKEIE 881

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAG 3628
            + E SS   EC+     D+  R+ W+ +  PL    R +T  D G   L I  +   D  
Sbjct: 882  VVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEA 939

Query: 3629 LYTCKATNRHGEATVSCKLQVK 3650
             Y C      G  +++ +L V+
Sbjct: 940  EYRCDIATDRGVVSMTTELIVE 961



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 8/88 (9%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG--- 2564
            P+  Q L    E+ E   A ++ RV   G P    EW+ +G +L+   RF    D     
Sbjct: 967  PVIIQPLKS-LEIKEENAARFDVRVR--GSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQD 1023

Query: 2565 --FVTLDINSVVANDAGLYMCKAINRAG 2590
                +L I  V+  DAG Y C A+N AG
Sbjct: 1024 KELYSLVIEDVIPEDAGEYECVAVNEAG 1051



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 2245 VTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDI 2304
            + E      V EG +   ECQ     D   RI +Y +   L  + RF   FD G  SL I
Sbjct: 873  IQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRI 930

Query: 2305 QHCVPEDAGEY 2315
               V +D  EY
Sbjct: 931  HDIVIDDEAEY 941



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 2/84 (2%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            +I + EG     E +     D+  R+ W KD  P+  S R  T F+ G  +L I  + + 
Sbjct: 879  EIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVID 936

Query: 978  DAGHYTCRAYNAIGQATTSANLTI 1001
            D   Y C      G  + +  L +
Sbjct: 937  DEAEYRCDIATDRGVVSMTTELIV 960



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 2/82 (2%)

Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
           E+ EG +   E Q +   D   R+ WYKD  P+  S R  + F+ G  SL I  +  +D 
Sbjct: 881 EVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDE 938

Query: 841 GSYTVRAVNKLGEAISTASIRV 862
             Y        G    T  + V
Sbjct: 939 AEYRCDIATDRGVVSMTTELIV 960



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 6/117 (5%)

Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE 1628
            +V++    AP     LK +E+ E Q    E  +    +   ++ W      +K   R T 
Sbjct: 1153 IVEKPEGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITT 1210

Query: 1629 TNNFGFVALDI-MSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK--KSIYLESQHE 1682
              +     L+I +SCL +D G Y C A+N  G+A T    +V+    K  ++E+ H+
Sbjct: 1211 VFDGETCVLNITVSCL-DDEGEYKCLAMNDFGKAATVAELLVNEALVKPKFIETTHD 1266



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 4/108 (3%)

Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE 1628
            +V+E   +     T+  + EI  G+   F  R+      T  V+WYH +  +    RF  
Sbjct: 1250 LVNEALVKPKFIETT-HDTEIITGESVWF--RVKYEGSPTPDVDWYHEDTLVSDTGRFLI 1306

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT-SGIAIVHSKKSI 1675
                    L I    P D G Y C   N  GE +T S + ++  KK I
Sbjct: 1307 NTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPI 1354



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 29/167 (17%), Positives = 69/167 (41%), Gaps = 4/167 (2%)

Query: 3927 IILQNQVPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLV 3986
            +I+++  P      + +   +A      S++ + E      D   PP F   +  +  L 
Sbjct: 1315 LIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTPPEFSPHV-GEGPLK 1373

Query: 3987 EMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEY 4046
              +      ++   G+P  +++WF + KP+    +    Y     ++      P+D+ +Y
Sbjct: 1374 ISDGGDLTLEVKITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKY 1433

Query: 4047 LCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEAS 4093
             C+ATN  G       +  +    ++ + + PK+++ ++    +E S
Sbjct: 1434 TCKATNKSGTTTRNINVDIS---ALMPEGEAPKYVEPLKSDEIVEDS 1477



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 42/201 (20%), Positives = 81/201 (40%), Gaps = 15/201 (7%)

Query: 3402 DSMVRRKDTSVEEEK-----GKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456
            + M   K T +E++K     G  P F+ P      L+  +       +  T +P  +++W
Sbjct: 1338 EDMTVSKLTVIEKKKPITDVGTPPEFS-PHVGEGPLKISDGGDLTLEVKITGEPKPEIQW 1396

Query: 3457 YWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
            + + K +K   + R         L I    P+D+ +Y C+A N  G      ++ +    
Sbjct: 1397 FKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDISA-- 1454

Query: 3517 NIILESQLPKGMEG-TIDKIAALEGYSGTV---DTLTPEAE--SGNPPEFTTTPSDLILS 3570
             ++ E + PK +E    D+I     ++  V    T  PE +    N P        +I  
Sbjct: 1455 -LMPEGEAPKYVEPLKSDEIVEDSSFTMNVKFTGTPIPEVQWFKENKPVREDDRVHIIRE 1513

Query: 3571 ENSSAHFECRLIPVNDSSMRV 3591
             +SS     + +P ++ S ++
Sbjct: 1514 SDSSTLVITKTVPDDEGSYKI 1534



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 2/95 (2%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGY 966
            + P    P+ D+I + EG  A  E  +   G     V W KD   +E   R++   +   
Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745

Query: 967  VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
              L I+S  + D   Y C   N  G       L +
Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIV 1780



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 41/168 (24%), Positives = 71/168 (42%), Gaps = 9/168 (5%)

Query: 3897 EDSGEYICRAVNDFGEDFTK--ATISCKKLPDIILQNQVPRGMKRSEALTQMEATIK-KY 3953
            +D+ E +    + F +D  K   TIS   L D  +  +V       EA+T  E  ++ K 
Sbjct: 2031 KDNKELVPDERHTFTKDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVKE 2090

Query: 3954 TSEVYLTEDDLYDVDKKQP-PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFN 4012
             +EV   E+    VD   P P  +  +  +  ++E ++ + EC ++  G P+ +V W+ +
Sbjct: 2091 AAEVTPVEEV---VDAAVPAPIIIKPLNDEIDVLEGDSVRLECVIS--GGPDAQVLWYKD 2145

Query: 4013 GKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
               L    R     D     +       +D  EY C  TN+ G  + K
Sbjct: 2146 DYLLEEDERIMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVK 2193



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%)

Query: 1847 ITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI 1906
            I + +   ++ EG S   EC+     D   R+ WY +   L    R+ T+ D G  +L I
Sbjct: 873  IQEYSKEIEVVEGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRI 930

Query: 1907 LTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
              +  +D  EY C    + G    +  L V+
Sbjct: 931  HDIVIDDEAEYRCDIATDRGVVSMTTELIVE 961



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 5/95 (5%)

Query: 3979 IQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG-----YVAM 4033
            IQ   SL   E       +   G P   VEWF +G+ L    RF  I D         ++
Sbjct: 970  IQPLKSLEIKEENAARFDVRVRGSPQPLVEWFKDGRQLQDLGRFMIIDDVDDQDKELYSL 1029

Query: 4034 NFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
                V PED+GEY C A N  G   + A ++   K
Sbjct: 1030 VIEDVIPEDAGEYECVAVNEAGKATSTATLQVLTK 1064



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 19/72 (26%), Positives = 35/72 (48%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            + W K+   +    R+    D    TL+I+    DD G+YTC   N +G+  ++A + +E
Sbjct: 1925 VTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVE 1984

Query: 2736 DRHWLLGESLHP 2747
            +   +  E+  P
Sbjct: 1985 ELEAVESEAEPP 1996



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/94 (23%), Positives = 37/94 (39%), Gaps = 1/94 (1%)

Query: 2365 PEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR 2424
            PE  + + ++ P F +    I   +  +       +   G P   VEW +++  +     
Sbjct: 58   PEEVDAMLKEEPTFLES-DEIKPFEVTEEGDIKLTVQVTGKPQPSVEWLKDDVPVSPDEH 116

Query: 2425 ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            IT T +    S+ I     +DEG Y    SN  G
Sbjct: 117  ITITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAG 150



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/118 (22%), Positives = 49/118 (41%), Gaps = 3/118 (2%)

Query: 760  ESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRI 819
            E +  +   +P+FI    D  E+  G +  F  +      PT  V+WY +   ++ + R 
Sbjct: 1248 ELLVNEALVKPKFIETTHDT-EIITGESVWFRVKYE--GSPTPDVDWYHEDTLVSDTGRF 1304

Query: 820  TSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQ 877
                     +L I  ++  D G+Y     N  GE ++ + + V  +     D+G P +
Sbjct: 1305 LINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEKKKPITDVGTPPE 1362



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGAR-LKSTFDFGLVTLSINSLRNDDSGIYTCKAT 2720
            L   V+    P  ++EW K+   L    R + S  D G+V L I  +   DSG+Y C+ +
Sbjct: 306  LRLTVKVTGKPFPEVEWTKDDKDLKEDDRVIISEQDDGIVVLRIKDVGAHDSGVYKCQVS 365

Query: 2721 NLLGEAVSTASIKIE 2735
            + +G +  +  + IE
Sbjct: 366  SDVGTSTKSFDVTIE 380



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            FI  L  +   E   +  EC+V  + +P  +I W      +    R  +  D     L+I
Sbjct: 1164 FIKPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDRITTVFDGETCVLNI 1221

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            T +  +D G Y C A N  G A T   L
Sbjct: 1222 TVSCLDDEGEYKCLAMNDFGKAATVAEL 1249



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 27/104 (25%), Positives = 38/104 (36%), Gaps = 2/104 (1%)

Query: 3546 DTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR 3605
            D    E   G  PEF      L + E      EC +    +   ++ W   G  +    R
Sbjct: 1150 DITIVEKPEGAAPEFIKPLKVLEVFETQPVRLECSVTGTPEP--QITWLKGGDVVKEDDR 1207

Query: 3606 VKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + T+ D    +L I      D G Y C A N  G+A    +L V
Sbjct: 1208 ITTVFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 33/104 (31%), Positives = 45/104 (43%), Gaps = 6/104 (5%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPN-LKVEWYWNGKSLKAGSRFRTF 3472
            E + + P F  PL + E L EG        L  TD  + + ++W+ + K L    R    
Sbjct: 1990 ESEAEPPRFVTPLKDQE-LEEGSTVDM---LVETDGTSPIHIKWFKDNKELVPDERHTFT 2045

Query: 3473 CDFGFVILEISPTYPEDSGEYL-CRAYNNYGEAVTTASMKVQGK 3515
             D     + ISP   ED   Y    A N  GEAVT A + V+ K
Sbjct: 2046 KDGNKHTMTISPVTLEDEAMYYKVVAENVAGEAVTDAEVIVEVK 2089



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 1978 PQFGK-PIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            P+F K P K+  +V  G  V L+ T+T    PT +VEW+ + +PV+   R +        
Sbjct: 2439 PEFQKEPEKSTFDVNTGDDVSLDLTVT--GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEH 2496

Query: 2036 ALDILYAYAEDTGTYMCKATNAVG 2059
            +L I     +D+G Y   A +  G
Sbjct: 2497 SLKIKGGKPDDSGKYTVVAESPAG 2520



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 2/67 (2%)

Query: 87  GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146
           G+ K   ++ G P P V W +   P+      ++   + T   SL+IK+    DEG YT 
Sbjct: 86  GDIKLTVQVTGKPQPSVEWLKDDVPVSPDEHITITEEDDT--YSLVIKEPTKKDEGTYTV 143

Query: 147 TARNQYG 153
              N+ G
Sbjct: 144 EVSNEAG 150



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 5/124 (4%)

Query: 3947 EATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMK 4006
            +AT K  T+   +  D    + + + P++V  ++S   +   E + F   +   G P  +
Sbjct: 1436 KATNKSGTTTRNINVDISALMPEGEAPKYVEPLKSDEIV---EDSSFTMNVKFTGTPIPE 1492

Query: 4007 VEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG--MDETKAVIK 4064
            V+WF   KP+   +R   I +     +      P+D G Y    +N +G  + E + V+ 
Sbjct: 1493 VQWFKENKPVREDDRVHIIRESDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVM 1552

Query: 4065 TTGK 4068
            T  +
Sbjct: 1553 TVSE 1556



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 3/95 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP +   LKS D++VE     +  +      P  +++WFK    +    R+    +   
Sbjct: 1460 EAPKYVEPLKS-DEIVEDSSFTMNVKFTGTPIP--EVQWFKENKPVREDDRVHIIRESDS 1516

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             TL I     DD G Y    +N  G+AVS A + +
Sbjct: 1517 STLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVV 1551



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIAS 1107
            P K T  +  G     +  V  +   T  VEW+ + K +    R++        +L I  
Sbjct: 2445 PEKSTFDVNTGDDVSLDLTVTGKP--TPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKG 2502

Query: 1108 VRAEDSGVYTVVARNAAG 1125
             + +DSG YTVVA + AG
Sbjct: 2503 GKPDDSGKYTVVAESPAG 2520



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 2/71 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            GD++  +  V  +  PT K+EWF ++KP+    R +        SL I     +DSG YT
Sbjct: 2455 GDDVSLDLTV--TGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYT 2512

Query: 2848 CKATNSKGSAT 2858
              A +  G  T
Sbjct: 2513 VVAESPAGRDT 2523



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 19/77 (24%), Positives = 33/77 (42%), Gaps = 2/77 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG ++  EC    + D   +I W+ ++ PL    R+++  D    SL I     +D   Y
Sbjct: 884  EGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEY 941

Query: 2847 TCKATNSKGSATTSGSL 2863
             C     +G  + +  L
Sbjct: 942  RCDIATDRGVVSMTTEL 958



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 19/88 (21%), Positives = 37/88 (42%), Gaps = 2/88 (2%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            + TVEG+++ ++  +   G     VEW+ + + +     +      D   L + S  P D
Sbjct: 1073 VHTVEGSDITMKVAVS--GTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSD 1130

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKD 1407
            +G Y C   N  G       + ++ K +
Sbjct: 1131 AGTYKCVTKNDSGTFTQMFDITIVEKPE 1158



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 3/93 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F+ PLK   ++ E Q    E  V    +  +T  W   G  +   +RI T  D     
Sbjct: 1162 PEFIKPLK-VLEVFETQPVRLECSVTGTPEPQIT--WLKGGDVVKEDDRITTVFDGETCV 1218

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            L+I     +D G Y  +A N  G+A   A + V
Sbjct: 1219 LNITVSCLDDEGEYKCLAMNDFGKAATVAELLV 1251



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 3/101 (2%)

Query: 1709 QAPVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY 1767
            +AP    P+ D I V E  +A  E   +  G P   V W ++   +E   R++   D   
Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLEC--VISGGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
              L ++    +D   Y C   N  G     + L V+   SL
Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVEEGISL 1786



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 8/148 (5%)

Query: 1536 CRSTTDIVRST--QNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEG 1592
            C    D V S    NEAG +     + +   H     ++ T  A P  T  L + E++E 
Sbjct: 1852 CAPDDDAVYSVVAMNEAGKD---TSKGKLLVHSRPKQEQPTEPAGPRITKELVDAEVEET 1908

Query: 1593 QRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTC 1652
                       VS+    V W  +   + + +R T   +     L I     +D G YTC
Sbjct: 1909 TPVTLVAEF--VSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTC 1966

Query: 1653 RAINALGEAVTSGIAIVHSKKSIYLESQ 1680
               N +G+  TS   IV   +++  E++
Sbjct: 1967 TVRNKMGDTSTSAEVIVEELEAVESEAE 1994



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 2/91 (2%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            GE+  F  +   +  P+  V+WY     +    RF    +     L I    P D G Y 
Sbjct: 1272 GESVWFRVKYEGSPTPD--VDWYHEDTLVSDTGRFLINTEEDTSTLIIEDVKPIDKGNYK 1329

Query: 3495 CRAYNNYGEAVTTASMKVQGKRNIILESQLP 3525
            C   N+ GE +T + + V  K+  I +   P
Sbjct: 1330 CIISNDAGEDMTVSKLTVIEKKKPITDVGTP 1360



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/96 (22%), Positives = 40/96 (41%), Gaps = 3/96 (3%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P  E PK++  ++   ++VE  S     +      P+  V+WF   K +    R     +
Sbjct: 1457 PEGEAPKYVEPLKS-DEIVEDSSFTMNVKFTGTPIPE--VQWFKENKPVREDDRVHIIRE 1513

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
                 L I     ++ G Y+ V +N  G+  ++A L
Sbjct: 1514 SDSSTLVITKTVPDDEGSYKIVLSNPFGKAVSEAEL 1549



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643
            V++    V W  +   ++  +RV    D     L I      D GLYTC   N+ G+ + 
Sbjct: 1918 VSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTST 1977

Query: 3644 SCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEE 3677
            S ++ V+  + +  E + P  F +  +  Q+LEE
Sbjct: 1978 SAEVIVEELEAVESEAE-PPRFVTPLKD-QELEE 2009



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 4/80 (5%)

Query: 2380 QPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTI 2438
            +P ++  ++  G     D  L   G PT KVEWF+++K ++ + R+  K  D  + S+ I
Sbjct: 2444 EPEKSTFDVNTGDDVSLD--LTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEH-SLKI 2500

Query: 2439 SHVRDEDEGVYMCRASNLLG 2458
               + +D G Y   A +  G
Sbjct: 2501 KGGKPDDSGKYTVVAESPAG 2520



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 3441 EARLTP--TDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAY 3498
            + RLT   T  P  +V W  +GK +               IL I    P+DSG Y C   
Sbjct: 192  DVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLT 251

Query: 3499 NNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530
            ++ G++  T S+ ++ +     ES+  K ++G
Sbjct: 252  SDVGKSTRTFSVDIESEGPAPKESEKRKLLKG 283



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 8/125 (6%)

Query: 1180 VQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDI 1239
            +Q  S    V EG ++ +EC  +  G    R+ W+ +   +    RF+T +D G  +L I
Sbjct: 873  IQEYSKEIEVVEGSSVTIEC--QSSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRI 930

Query: 1240 IHATSADTGEYTVRAVNHLG--SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARR 1297
                  D  EY        G  S  T  IV       ++        I++    E+AAR 
Sbjct: 931  HDIVIDDEAEYRCDIATDRGVVSMTTELIVEEAVLMPVIIQPLKSLEIKE----ENAARF 986

Query: 1298 TKQVR 1302
              +VR
Sbjct: 987  DVRVR 991



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 3976 VTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNF 4035
            + +   +  +VE  +   ECQ +  G  + ++ W+ +  PL    RF   +D G  ++  
Sbjct: 873  IQEYSKEIEVVEGSSVTIECQSS--GAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRI 930

Query: 4036 GWVYPEDSGEYLC 4048
              +  +D  EY C
Sbjct: 931  HDIVIDDEAEYRC 943



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 2/74 (2%)

Query: 2920 EHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYER 2979
            E ++VEG  + +E Q       D +I WY +   L    RF+   D G  +L + D+   
Sbjct: 879  EIEVVEGSSVTIECQ--SSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVID 936

Query: 2980 DSGIYTCKAYNKRG 2993
            D   Y C     RG
Sbjct: 937  DEAEYRCDIATDRG 950



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 17/48 (35%), Positives = 22/48 (45%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583
            G    R  WY + V L    RF T  D G  +L I+ +V +D   Y C
Sbjct: 896  GAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEYRC 943



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 20/79 (25%), Positives = 32/79 (40%)

Query: 3833 ITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDIL 3892
            I+++    V   EG     +V     P+  +EWY++ + L +   Y     +    L I 
Sbjct: 1065 ISELDKTPVHTVEGSDITMKVAVSGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTIT 1124

Query: 3893 YVYAEDSGEYICRAVNDFG 3911
                 D+G Y C   ND G
Sbjct: 1125 SASPSDAGTYKCVTKNDSG 1143



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 11/139 (7%)

Query: 1991 EGHPVHLEATLTPVNDPTMRVEWYCNGRPV--QQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            EG  + ++  ++    P   VEWY + R +  ++ +  KTT D  Y  L I  A   D G
Sbjct: 1077 EGSDITMKVAVS--GTPRTEVEWYKDDRKLSNRKPYVIKTTVD-DY-ELTITSASPSDAG 1132

Query: 2049 TYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE-RPKPIEEEQPGQ 2107
            TY C   N  G       + +  K     +    + +K ++ LE +E +P  +E    G 
Sbjct: 1133 TYKCVTKNDSGTFTQMFDITIVEKP----EGAAPEFIKPLKVLEVFETQPVRLECSVTGT 1188

Query: 2108 RPVFLTALTSLENLKEGDR 2126
                +T L   + +KE DR
Sbjct: 1189 PEPQITWLKGGDVVKEDDR 1207



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 3/95 (3%)

Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            V   E   PE+I P+    ++ E Q + LE  V     P+ +I W   G V+++  R   
Sbjct: 1154 VEKPEGAAPEFIKPLKVL-EVFETQPVRLECSVT--GTPEPQITWLKGGDVVKEDDRITT 1210

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
              D     L++      D G Y C A N  G+A T
Sbjct: 1211 VFDGETCVLNITVSCLDDEGEYKCLAMNDFGKAAT 1245



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 5/108 (4%)

Query: 1976 EKPQFGKPIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGY 2034
            E P   KP+ +  +V EG    LE  ++    P   V WY +   +++  R     D   
Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDE 2082
              L I  A  +D   Y C  TN  G     + + V+   G+ L  + E
Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIVE--EGISLPVIKE 1791



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 5/125 (4%)

Query: 3701 IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYI 3760
            + D IDV EG     +C +   G P   + W+ +        RV    D     L I   
Sbjct: 1696 LNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDGDQHTLIIQSA 1753

Query: 3761 YARDAGEYTCRATNKWGSATTTAKITCSAKRDI-VLESQLPQGMSGEKIKELERGRISDA 3819
               D  EY C  TN  GS     ++       + V++  L    + E   E+ R  I  A
Sbjct: 1754 ELDDEAEYKCVVTNIAGSVDVKTELIVEEGISLPVIKEGLKDTEANE--GEIVRFDIRVA 1811

Query: 3820 PKEEP 3824
             K EP
Sbjct: 1812 GKPEP 1816



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
            G +   +  + G PTP V W +   P+    +  ++  +   + SL IK   P D G+YT
Sbjct: 2455 GDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDD--EHSLKIKGGKPDDSGKYT 2512

Query: 146  CTARNQYG 153
              A +  G
Sbjct: 2513 VVAESPAG 2520



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 35/147 (23%), Positives = 57/147 (38%), Gaps = 4/147 (2%)

Query: 1168 QIEEISKSKPVFVQPLSNPP-PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRF 1226
            +++ + K +P F++     P  V+E  +I L  ++   G P   VEW  +   V+     
Sbjct: 60   EVDAMLKEEPTFLESDEIKPFEVTEEGDIKLTVQVT--GKPQPSVEWLKDDVPVSPDEHI 117

Query: 1227 KTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE-RSDIVTDTQNEQAI 1285
                +    +L I   T  D G YTV   N  G    +  V V + R  I  D    + I
Sbjct: 118  TITEEDDTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFI 177

Query: 1286 EQIQLLEDAARRTKQVREDITVMQAPQ 1312
            E    +   +     VR  + V   P+
Sbjct: 178  EDGSFVPFQSTDEGDVRLTVKVTGKPE 204



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/130 (21%), Positives = 54/130 (41%), Gaps = 5/130 (3%)

Query: 3809 KELERGR--ISDAPKEE-PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            K+  +G+  +   PK+E P     P+   ++    VEE+  V      E   + +  + W
Sbjct: 1870 KDTSKGKLLVHSRPKQEQPTEPAGPRITKELVDAEVEETTPVTLVA--EFVSEGETSVTW 1927

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             ++   + + +R     D    +L I     +D G Y C   N  G+  T A +  ++L 
Sbjct: 1928 TKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELE 1987

Query: 3926 DIILQNQVPR 3935
             +  + + PR
Sbjct: 1988 AVESEAEPPR 1997



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 16/64 (25%), Positives = 30/64 (46%), Gaps = 2/64 (3%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + EG +   +C+    G    ++ W++++  + DS R     D G  S+ I  +  +DE 
Sbjct: 882  VVEGSSVTIECQ--SSGAEDARITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEA 939

Query: 2448 VYMC 2451
             Y C
Sbjct: 940  EYRC 943



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 19/67 (28%), Positives = 29/67 (43%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDI 4169
            P +   L D + V EG+ AR  C ++G P   V W  +   +    R     DG  H  I
Sbjct: 1690 PFIIKPLNDEIDVLEGDSARLECVISGGPDAHVFWYKDDYLLEEDERVSYETDGDQHTLI 1749

Query: 4170 PKTRQYD 4176
             ++ + D
Sbjct: 1750 IQSAELD 1756



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 2/80 (2%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493
            EG +   E + +  +D   ++ WY +   L    RF T  D G   L I     +D  EY
Sbjct: 884  EGSSVTIECQSSGAEDA--RITWYKDDVPLGDSPRFETAFDNGLCSLRIHDIVIDDEAEY 941

Query: 3494 LCRAYNNYGEAVTTASMKVQ 3513
             C    + G    T  + V+
Sbjct: 942  RCDIATDRGVVSMTTELIVE 961



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 2/72 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG +I  +  V  S  P  ++EW+ +++ L +   Y          L IT     D+G Y
Sbjct: 1077 EGSDITMKVAV--SGTPRTEVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTY 1134

Query: 2847 TCKATNSKGSAT 2858
             C   N  G+ T
Sbjct: 1135 KCVTKNDSGTFT 1146



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 16/50 (32%), Positives = 23/50 (46%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            +VEWY +++ L +   +          L I S  P D+GTY C   N  G
Sbjct: 1094 EVEWYKDDRKLSNRKPYVIKTTVDDYELTITSASPSDAGTYKCVTKNDSG 1143



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 4/129 (3%)

Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
            +E  T    P+ ++ L + E  E T V L       G+ +  V W  +   +   +R   
Sbjct: 1885 QEQPTEPAGPRITKELVDAEVEETTPVTLVAEFVSEGETS--VTWTKDAHRVVADNRVTI 1942

Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLE-- 1419
              +     L +     +D G+YTC   N++G+  TS  + V   + +  E++ P  +   
Sbjct: 1943 KTDETSSTLAISKSDVDDEGLYTCTVRNKMGDTSTSAEVIVEELEAVESEAEPPRFVTPL 2002

Query: 1420 KIQYLEDTS 1428
            K Q LE+ S
Sbjct: 2003 KDQELEEGS 2011



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 18/55 (32%), Positives = 27/55 (49%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718
            G PT K+EW K+ + ++ + R     +    SL +      DSG+YT  A S  G
Sbjct: 2466 GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAG 2520



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/110 (21%), Positives = 50/110 (45%), Gaps = 6/110 (5%)

Query: 2629 VPEMFVDTG-VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
            V E+ V+   V+   I TTH     +++ G+ V+   + E    P+  ++W+     ++ 
Sbjct: 1246 VAELLVNEALVKPKFIETTH---DTEIITGESVWFRVKYEGSPTPD--VDWYHEDTLVSD 1300

Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
              R     +    TL I  ++  D G Y C  +N  GE ++ + + + ++
Sbjct: 1301 TGRFLINTEEDTSTLIIEDVKPIDKGNYKCIISNDAGEDMTVSKLTVIEK 1350



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 7/114 (6%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+++  L    ++ E  S     +    P P   V+W+   K ++   R     +   
Sbjct: 1460 EAPKYVEPLKSD-EIVEDSSFTMNVKFTGTPIPE--VQWFKENKPVREDDRVHIIRESDS 1516

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKI 1955
            + L I     +D G Y     N  G+AVS   L V +    + +++ E  + K+
Sbjct: 1517 STLVITKTVPDDEGSYKIVLSNPFGKAVSEAELVVMT----VSEAEDEGIIPKV 1566



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/85 (25%), Positives = 35/85 (41%), Gaps = 2/85 (2%)

Query: 768  QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827
            + P  I+PL D  ++ EG +A  E  ++    P   V WYKD   +    R++   +   
Sbjct: 1688 EAPFIIKPLNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDGDQ 1745

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLG 852
             +L I     +D   Y     N  G
Sbjct: 1746 HTLIIQSAELDDEAEYKCVVTNIAG 1770



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 3/99 (3%)

Query: 3683 EEITIEDEKPNPPRFTVEI-KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            E +     K   P F  E  K   DV  G  V  D  V   G PT +++WF + +P    
Sbjct: 2427 EAVLTVKPKEIAPEFQKEPEKSTFDVNTGDDVSLDLTV--TGKPTPKVEWFKDDKPVKGT 2484

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
             R+         +L I      D+G+YT  A +  G  T
Sbjct: 2485 RRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAGRDT 2523



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 5/124 (4%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVA 720
            E V +    + W K+   + A +R T        +L +   ++ D G YTC   +  G  
Sbjct: 1916 EFVSEGETSVTWTKDAHRVVADNRVTIKTDETSSTLAISKSDVDDEGLYTCTVRNKMGDT 1975

Query: 721  ETKAVLHVTPRATIERTSQHPETLQYI--QQLEDYSKYQHQESIEEQTSQRPQFIRPLQD 778
             T A + V     +E  ++ P  +  +  Q+LE+ S     + + E     P  I+  +D
Sbjct: 1976 STSAEVIVEELEAVESEAEPPRFVTPLKDQELEEGSTV---DMLVETDGTSPIHIKWFKD 2032

Query: 779  LGEL 782
              EL
Sbjct: 2033 NKEL 2036



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 3/72 (4%)

Query: 2784 VCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDS 2843
            V +EGD    +  V+ +  P   +EW  ++ P+        T +    SL I    ++D 
Sbjct: 82   VTEEGD---IKLTVQVTGKPQPSVEWLKDDVPVSPDEHITITEEDDTYSLVIKEPTKKDE 138

Query: 2844 GIYTCKATNSKG 2855
            G YT + +N  G
Sbjct: 139  GTYTVEVSNEAG 150



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/93 (23%), Positives = 33/93 (35%), Gaps = 2/93 (2%)

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158
            P+      + P  +  L    ++ EGD A  EC +    D H  + W+ +   +    R 
Sbjct: 1680 PVSFTPAEEAPFIIKPLNDEIDVLEGDSARLECVISGGPDAH--VFWYKDDYLLEEDERV 1737

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
                D     L I     +D   Y C  TN  G
Sbjct: 1738 SYETDGDQHTLIIQSAELDDEAEYKCVVTNIAG 1770



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 2/88 (2%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDF 1232
            ++  P  ++PL++   V EG +  LEC +   G P   V W+ +   +    R     D 
Sbjct: 1686 AEEAPFIIKPLNDEIDVLEGDSARLECVIS--GGPDAHVFWYKDDYLLEEDERVSYETDG 1743

Query: 1233 GFVALDIIHATSADTGEYTVRAVNHLGS 1260
                L I  A   D  EY     N  GS
Sbjct: 1744 DQHTLIIQSAELDDEAEYKCVVTNIAGS 1771



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 27/124 (21%), Positives = 47/124 (37%), Gaps = 5/124 (4%)

Query: 3056 DIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKT 3115
            D +D+ EG  A  E  +  +G     + W+ +   +E   R+          L I   + 
Sbjct: 1698 DEIDVLEGDSARLECVI--SGGPDAHVFWYKDDYLLEEDERVSYETDGDQHTLIIQSAEL 1755

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
             D   Y C  TN  G   + VK E + +     P     +++ E   +G+   F+  V  
Sbjct: 1756 DDEAEYKCVVTNIAG--SVDVKTELIVEEGISLPVIKEGLKDTEA-NEGEIVRFDIRVAG 1812

Query: 3176 VDDP 3179
              +P
Sbjct: 1813 KPEP 1816



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/85 (27%), Positives = 33/85 (38%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            PEF   P       N+       L      + +VEWF + KP+    R++         L
Sbjct: 2439 PEFQKEPEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSL 2498

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEAT 3642
            +I G    D+G YT  A +  G  T
Sbjct: 2499 KIKGGKPDDSGKYTVVAESPAGRDT 2523


>SB_47305| Best HMM Match : I-set (HMM E-Value=0)
          Length = 5832

 Score =  180 bits (437), Expect = 3e-44
 Identities = 124/408 (30%), Positives = 190/408 (46%), Gaps = 24/408 (5%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            KP + T  M+ C   E E A F  EF G+P P I+W+    PI     F +        L
Sbjct: 825  KPEVITS-MRDCDCVEEETASFHCEFSGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSL 883

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I  + +ED+  +  VA N  G     A L V EK          P F      ++   G
Sbjct: 884  AISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEKH-------FAPEFEDWKDTIDALDG 936

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
            Q V + T V G    ++ WLK+G++++  +  +I      + L++ +  P+D+G Y C A
Sbjct: 937  QDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRA 996

Query: 4589 INSAGEARCDAECVV-SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
             N+AG    D    V +L    D P   +K        +EP++   + EG   + SC + 
Sbjct: 997  KNNAGIVSKDVTITVEALQKKGDTPTFMSK--------LEPIE---ITEGDDFQLSCNVT 1045

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G+P P VQW++ + LIKPS+ F+ S   +   L + EA  +D+G YKCV  N+ G  +V+
Sbjct: 1046 GRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFG--SVS 1103

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            +K  VT   +      L  + D+   EG  A F  +I +  KP I+W      I +   F
Sbjct: 1104 SKADVTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRF 1163

Query: 4768 QMIHEGNNA--VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            ++  +  N   +L I +   +D GT  C AT AAG+    A L V+ K
Sbjct: 1164 KIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211



 Score =  175 bits (426), Expect = 7e-43
 Identities = 116/403 (28%), Positives = 184/403 (45%), Gaps = 21/403 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F K+++P  V   E+A   +E  G+P P + WY++  P+  +   Q+ +   +  L I
Sbjct: 631  PEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDLVPLLETRSIQLKSVGDEHTLEI 690

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                 +D   +   A N+ GTA  S ++ V+    QG      P+ T    ++    G+ 
Sbjct: 691  INATPDDEGKYKCEATNKAGTAFRSFDIKVKVAEPQGE----TPTITTEMTDIQAIDGED 746

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
             +L   VTG    +V W K+GK ++ + R     E+    L       +D G+Y+CV  N
Sbjct: 747  CKLICHVTGEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISN 806

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
              G     AE  V   + K             PE+I  ++D    E +   F C+  GKP
Sbjct: 807  VFGSVSSAAEVKVEDRSLK-------------PEVITSMRDCDCVEEETASFHCEFSGKP 853

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             P ++W+ G   I P   F ++   +  +L IS+   ED G+YKCVA N+AG+ T  A+L
Sbjct: 854  EPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAEL 913

Query: 4711 KVTQPDQADNLPALTPLRDIV-VYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            KV +   A   P     +D +   +GQ     T +  K KP I WL++G  +  T   Q+
Sbjct: 914  KVNEKHFA---PEFEDWKDTIDALDGQDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQI 970

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
               G+   L++     ED G +TCRA   AG V     + V++
Sbjct: 971  KCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEA 1013



 Score =  171 bits (415), Expect = 2e-41
 Identities = 111/392 (28%), Positives = 181/392 (46%), Gaps = 20/392 (5%)

Query: 4419 PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDS 4478
            P R  E          +G+P P + WYR++  + +    ++          +  V   D+
Sbjct: 1812 PFRAKEKSDLEVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDA 1871

Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
              +   A+NR G+A  + N+ +E  + +       PSFT T + ++VT G+      +V 
Sbjct: 1872 GSYRCEAKNRVGSATRNFNVEIEVPKARDEA----PSFTTTLKPIDVTEGENHTFICRVH 1927

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
                  V W +N  ++ PD R++   +  TY L++ +   +D+G+YEC+A N  G+A C 
Sbjct: 1928 ARPEPSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCT 1987

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            AE  V+        K + K     P I E  K   V+EG       K+ G P+PTV+WY 
Sbjct: 1988 AEMTVN--------KREVK-----PVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYH 2034

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718
            G   +     FQ+++  D +TL I +   +    YKCVA+N+AGR T  A L +T+ + A
Sbjct: 2035 GSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREYA 2094

Query: 4719 DNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778
                     R I V EGQ A     I ++  P ++W +   L+       +   G    L
Sbjct: 2095 PEFEDFDEKR-IAVREGQNAITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYL 2153

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             I     +D GT+ C+AT + G   TS +++V
Sbjct: 2154 EIRKATLDDAGTYICKATNSIG--STSRRIIV 2183



 Score =  166 bits (403), Expect = 4e-40
 Identities = 120/410 (29%), Positives = 178/410 (43%), Gaps = 21/410 (5%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K    P F +K++     E EQ  FE+   G P P+++WYR    IK+   F I      
Sbjct: 528  KAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEEN 587

Query: 4466 SI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNV 4523
             +  L+I +   EDS  +  VA N  G      NL V EK       +V P F    + +
Sbjct: 588  DMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNEK-------VVQPEFDKEVKPI 640

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
             V  G+      ++ G     V W K+   +      ++      +TL I+ A P D GK
Sbjct: 641  EVKHGEEATTSLEIKGKPKPKVTWYKDLVPLLETRSIQLKSVGDEHTLEIINATPDDEGK 700

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y+C A N AG A    +  V +     +P+ +T      P I   + D    +G+  +  
Sbjct: 701  YKCEATNKAGTAFRSFDIKVKVA----EPQGET------PTITTEMTDIQAIDGEDCKLI 750

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C + G+P P V+W+K  K +K +     S       L       ED G YKCV  N  G 
Sbjct: 751  CHVTGEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGS 810

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
            V+ AA++KV   D++     +T +RD    E + A F  + + K +P I+W      I  
Sbjct: 811  VSSAAEVKV--EDRSLKPEVITSMRDCDCVEEETASFHCEFSGKPEPEIEWFCGPNPIVP 868

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               F +  EGN   L I +   ED G + C A+ AAG+  T A+L V  K
Sbjct: 869  GGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score =  165 bits (401), Expect = 8e-40
 Identities = 180/759 (23%), Positives = 309/759 (40%), Gaps = 95/759 (12%)

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYD 4176
            + + V+E +       VTG+PKP V W  +G  + +  + KL   G  H   IPK    D
Sbjct: 387  EPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTND 446

Query: 4177 TGKIEVIXXXXXXXXXXXXXLKVIPRHDD---YRGVL-----KNAPRPWYDETTQYQRTE 4228
             G+                 + V+P+        G++     K     W   TT     E
Sbjct: 447  EGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGE 506

Query: 4229 TELEKTFEERQVLQRQGVIDHRPELKPKVIKE-----------------------PETEW 4265
             +++ T E   V     +   + ++KP+ +++                       P  EW
Sbjct: 507  YKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEW 566

Query: 4266 QQSVKRKKNEEYYNKLQELENEQ---VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRY 4322
             +   R K+   +   +  EN+    VI E+R  +S      P   V SN   K+ A   
Sbjct: 567  YRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSG-----PYKCVASNDAGKTTALL- 620

Query: 4323 EDNLDQTEEVTEQRVQKKVTQKP-RIPDPSEST----VHGKE----------VHVAKQKQ 4367
              NLD  E+V +    K+V  KP  +    E+T    + GK           V + + + 
Sbjct: 621  --NLDVNEKVVQPEFDKEV--KPIEVKHGEEATTSLEIKGKPKPKVTWYKDLVPLLETRS 676

Query: 4368 TQKEVVGDKEITRKITSTE------TTEIEHKAQTQERVVEGPVKPSKP----PIFTKKM 4417
             Q + VGD+     I +T         E  +KA T  R  +  VK ++P    P  T +M
Sbjct: 677  IQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVKVAEPQGETPTITTEM 736

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI-LIIRQVFVE 4476
               +  + E  +      GEP P ++W+++  P+K +    + +F  + I L  R + +E
Sbjct: 737  TDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPLKANHRL-VPSFEERMIALSFRPIKLE 795

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D   +  V  N  G+   +A + VE++        + P    + ++ +    +      +
Sbjct: 796  DMGRYKCVISNVFGSVSSAAEVKVEDRS-------LKPEVITSMRDCDCVEEETASFHCE 848

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
             +G    ++ W      + P  R  + EE    +L I +   +D+G Y+CVA N+AG+  
Sbjct: 849  FSGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTT 908

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQ 4655
              AE  V+               +  PE  E  KD I A +GQ +  S  + GKP P + 
Sbjct: 909  TRAELKVN-------------EKHFAPE-FEDWKDTIDALDGQDVNISTWVRGKPKPEIV 954

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            W K  + ++ + + Q+    D + L + +  PED G Y C A N+AG V+    + V   
Sbjct: 955  WLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEAL 1014

Query: 4716 DQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
             +  + P  ++ L  I + EG   Q    +T + +P +QW R+  LI  +  F+  ++GN
Sbjct: 1015 QKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGN 1074

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             + L +     +D G + C  T   G V + A + V  K
Sbjct: 1075 VSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113



 Score =  163 bits (397), Expect = 2e-39
 Identities = 113/394 (28%), Positives = 175/394 (44%), Gaps = 18/394 (4%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSP-DFQIHTFSTKSILI 4469
            P F  +    RV E  +A    E  G+P P + WY+++  I +   +  I++  +     
Sbjct: 1215 PSFHGRQGRLRVKEGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFT 1274

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I+Q   ED   +   A N  GTA  +  + VE K+      ++ P      Q  +VT G 
Sbjct: 1275 IKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEV----MIAPEIRQQLQAEDVTEGD 1330

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
              RL  KV+G     + WLKN + +  + R K   +  T TL I      D+  Y+ V  
Sbjct: 1331 DCRLTCKVSGYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVR 1390

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N AGE    A+  V    TK             PE++E +KD    EG    F+ K+ G 
Sbjct: 1391 NDAGEVSSSAKLKVIRKCTK-------------PEVLEKMKDVKGVEGDEATFNVKLSGY 1437

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P P ++WY G   I+    ++ SR   +Y+L I +   +D G YKC+A N AG+VT  A+
Sbjct: 1438 PSPDIEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAE 1497

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            L+V + D A        L  + +   QP +    +  + KPT+ W + G  + +    ++
Sbjct: 1498 LEVKERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEI 1557

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
               G    L I  + EED G++ C A    G  E
Sbjct: 1558 RSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAE 1591



 Score =  159 bits (387), Expect = 4e-38
 Identities = 112/393 (28%), Positives = 178/393 (45%), Gaps = 24/393 (6%)

Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFA 4482
            E  +ARF+V  +G P P ++WY+    I +S   +I      K  LII+ +  +D+  + 
Sbjct: 4    ESGEARFDVTIEGYPKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYK 63

Query: 4483 AVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP 4542
             VA N  G      +L V+EK+      I P       + + V  G+ V LD  +TG   
Sbjct: 64   CVATNDAGQTSLRGDLSVKEKQ------IAPQIKEKEQEPIEVFEGESVNLDLTITGKPK 117

Query: 4543 IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             +V W K+GK ++      +   D +Y L I +A P DSGKY+C A N  G +  D +  
Sbjct: 118  PEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVN 177

Query: 4603 VSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
            V             K     P +   LK   V EG+  +F+C + GKP P + WYK  + 
Sbjct: 178  V-------------KVKGKAPTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQP 224

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
            IK  +  + S      TL I +   +D+G YK    N  G ++  A L+VT P  A    
Sbjct: 225  IKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVT-PKPA-KPE 282

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEG--NNAVLLI 4780
             +  + ++   EG  A F+ +      P  +W  +   I  +  F++  +     + L+I
Sbjct: 283  VVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVI 342

Query: 4781 GNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +   +D+G + C A+  AG+    A L VK+K
Sbjct: 343  SDLRLDDSGAYQCIASNEAGECNLRADLKVKNK 375



 Score =  155 bits (377), Expect = 6e-37
 Identities = 112/411 (27%), Positives = 181/411 (44%), Gaps = 25/411 (6%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K   P I  K+ +P  VFE E    ++   G+P P + WY++  P++ +    + +    
Sbjct: 84   KQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSIDLKSTDDS 143

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
              L I +    DS  +   A+N+ GT+    ++ V+ K +        P+ T   +   V
Sbjct: 144  YFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGK-------APTVTSELKPDKV 196

Query: 4526 TSGQLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
              G+  +    VTG  KP+ + W K+G+ ++ D R K   +  T TLLI +    D G Y
Sbjct: 197  QEGEQYKFTCAVTGKPKPV-ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTY 255

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
            +    N  G     A+  V+       PKP      A PE++  +++    EG    F  
Sbjct: 256  KVEITNDLGSISSTADLEVT-------PKP------AKPEVVRKMENVESVEGSDAFFEV 302

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT--LRISEAFPEDEGDYKCVAYNSAG 4702
            K  G P+P  +W+   K I+PS  F+++    E T  L IS+   +D G Y+C+A N AG
Sbjct: 303  KFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAG 362

Query: 4703 RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
               + A LKV     A    A   L  I V E Q    +  +T   KP + W ++G  + 
Sbjct: 363  ECNLRADLKVKNKPFAPEF-ADGDLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLH 421

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +T   ++   G+   L I      D G + C A+   G  + + K+ V  K
Sbjct: 422  DTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPK 472



 Score =  155 bits (375), Expect = 1e-36
 Identities = 106/379 (27%), Positives = 172/379 (45%), Gaps = 21/379 (5%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I WY++  P+ ++    I +      L I  +  ED+  +   A NR G A  S
Sbjct: 2861 GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              + V   + +G      PSF+L  + +        +L   V+G     + W KNGK V+
Sbjct: 2921 FEVDVTAPKVKGEA----PSFSLELRPIAAIEEFDSKLICHVSGKPKPQIKWTKNGKPVE 2976

Query: 4556 PDIRNKILEEDGTYTLL-ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
             D R +  + DG    L I +    D+G YEC+A N+AG     A   VS          
Sbjct: 2977 SDGRLRT-DYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVS---------- 3025

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
                 N  P I   L D    EG+   F  ++ G P PTV+W+KG   I   + +Q+   
Sbjct: 3026 ---RRNMRPLITHKLHDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGRRYQLMSN 3082

Query: 4675 ADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV 4732
             ++  ++L +S+   +D+G YKCVA N AG+ +  A L V   D           + ++V
Sbjct: 3083 EEQGKHSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIARDFGPEFDEEESPKPVIV 3142

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
             EG+ AQ    +  + K  ++W ++G  + ++    +   GN+  L+I +   ED G++ 
Sbjct: 3143 NEGEEAQMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYK 3202

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C A++  G+   +  L VK
Sbjct: 3203 CVASSTNGRSSRTFDLSVK 3221



 Score =  155 bits (375), Expect = 1e-36
 Identities = 116/413 (28%), Positives = 176/413 (42%), Gaps = 21/413 (5%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            ++ P    K P F K++ P    E +  +F  +  G P P I+W R+   +++       
Sbjct: 5239 IQAPEAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGYPEPEIEWTRDGVSMESDERVTTW 5298

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                 S L I      DS ++    +N  G A  SA LVV  K ++       P  +   
Sbjct: 5299 YDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKTQR-------PRLSDNM 5351

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580
            + +  T G   R +  +  T    + W K+   ++   R  + EEDG YTL+I E    D
Sbjct: 5352 KELFATVGGEARFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSD 5411

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
            SG Y+ VA N AG+        V           +T A   P    E L+  +  EG+ +
Sbjct: 5412 SGTYKFVASNKAGKTTFLGYLEV---------MEKTVAPEFPDR--ETLEQVVGVEGREV 5460

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            E S  + G P P+V+WYK  KL+  SK   +S + D + + I  A  E  G Y+C A NS
Sbjct: 5461 ELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEATNS 5520

Query: 4701 AGRV--TVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
             G         ++   P +    PA T PL+ I + EG   +F  +IT    P ++W R+
Sbjct: 5521 NGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVPVVEWYRD 5580

Query: 4758 GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
               +      +   +G   +LL+  T   D G F C      G V +SA L V
Sbjct: 5581 DRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633



 Score =  151 bits (367), Expect = 1e-35
 Identities = 108/406 (26%), Positives = 172/406 (42%), Gaps = 16/406 (3%)

Query: 4408 SKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSI 4467
            +KP +  +KM      E  + R EV   G P+P ++W+R+N  + N+  + I      S 
Sbjct: 4847 TKPEV-AEKMTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTST 4905

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L+IR     D+  +  +  N  G      NL++ E+         P       + V V  
Sbjct: 4906 LVIRNCTTNDTGPYKVIGTNECGIGGAVLNLIIHERE------FGPEFIDEEGEYVKVVR 4959

Query: 4528 GQ-LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             + +  +   V G    +V W K+G  +    R        T+ L I     +D+G Y C
Sbjct: 4960 SEGVANITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMC 5019

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAAN-APPEIIEPLKDKIVAEGQAIEFSCK 4645
             A +  G  +C   C++ + A    PK +        P I   ++D    EG  I F   
Sbjct: 5020 EARSKLG--KCFRSCILDVQAV---PKEEVDHGQIVKPVITRKIRDAQGEEGSNIRFEIH 5074

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            +   P P V+WY+G   +     +Q+S     Y+L I+    +D G YK VA N AG  T
Sbjct: 5075 VKSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSST 5134

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
              A++ V     A  +  +T    I +  G        I  K KP++ W ++G  I  + 
Sbjct: 5135 SRAEVVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIRGKPKPSVVWYKDGNKILTSR 5194

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + Q+   G+   L+I  T  E  GT++C AT+  G   TSAK  V+
Sbjct: 5195 NVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLG--NTSAKFDVQ 5238



 Score =  150 bits (363), Expect = 3e-35
 Identities = 117/406 (28%), Positives = 177/406 (43%), Gaps = 22/406 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS--IL 4468
            P   +KM   R  E  +A F V+ D  P P I+WY     I +   F+I T       IL
Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCSYIL 1176

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I  V ++D+      A N  G     A+L VEEK        V PSF      + V  G
Sbjct: 1177 FIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKN-------VAPSFHGRQGRLRVKEG 1229

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECV 4587
            +   +  +++G     V W K+   +  + RN  I     +Y   I +A P+D G Y+C 
Sbjct: 1230 REASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCE 1289

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N  G A        + P   +  K +   A   PEI + L+ + V EG     +CK+ 
Sbjct: 1290 ARNDVGTA------FETFPIDVE-VKQEVMIA---PEIRQQLQAEDVTEGDDCRLTCKVS 1339

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P PT++W K ++L+  +  F+        TL I      D   YK V  N AG V+ +
Sbjct: 1340 GYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSS 1399

Query: 4708 AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
            AKLKV +  +      L  ++D+   EG  A F  +++    P I+W      I +   +
Sbjct: 1400 AKLKVIR--KCTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRY 1457

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +   +     L I +   +D GT+ C A+  AG+V   A+L VK +
Sbjct: 1458 KFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKER 1503



 Score =  148 bits (359), Expect = 9e-35
 Identities = 107/380 (28%), Positives = 164/380 (43%), Gaps = 16/380 (4%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA--K 4493
            G P P + WYR+   + ++    I +      + I  + +ED+  +   A +R GTA   
Sbjct: 3408 GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRS 3467

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
            C+  + V          I          +V    G  V+  T++TG     V W +   K
Sbjct: 3468 CTLEIKVPSMGGPEEKKISKALIGQGDNDVQAVEGWKVQFQTRITGYPYPHVEWYRGTIK 3527

Query: 4554 VQPDIRNKILE--EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            +    + KI +  EDG Y+L++ +    D G Y+C+A NSAG + C     V     KDK
Sbjct: 3528 LHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDV-----KDK 3582

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671
                  A   P    E  ++  V EGQ I     I  KP   V WYK  +L++ +K   +
Sbjct: 3583 QY----APEIPGH--EDRQELNVPEGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDI 3636

Query: 4672 SRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLRDI 4730
                D Y L I  A PED G YKC   ++ G  +    +K   PD +   P  L+ L  +
Sbjct: 3637 RSRGDHYYLVIPSAAPEDSGLYKCEGVSTLGTSSKTFDVKAGVPDGSRVTPKFLSHLNSL 3696

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V EG  A+   ++  K +PT++W ++  LI      +    GN   L+      +D G 
Sbjct: 3697 DVDEGDSAKLTCKMFGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGA 3756

Query: 4791 FTCRATTAAGQVETSAKLVV 4810
            + C AT   G   +SA +VV
Sbjct: 3757 YRCTATNQEGSTSSSAVIVV 3776



 Score =  148 bits (358), Expect = 1e-34
 Identities = 106/388 (27%), Positives = 173/388 (44%), Gaps = 23/388 (5%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            V  P    + P F+ +++P    E   ++      G+P P IKW +   P+++    +  
Sbjct: 2925 VTAPKVKGEAPSFSLELRPIAAIEEFDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTD 2984

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                 + L I QV  +D+  +  +A N  GT   SA L V   RR  R     P  T   
Sbjct: 2985 YDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVS--RRNMR-----PLITHKL 3037

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL--EEDGTYTLLILEAYP 4578
             ++    G+  R D +VTG     V W K    +    R +++  EE G ++L++ +   
Sbjct: 3038 HDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNA 3097

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
             D G Y+CVA N AG+A   A   V     +D   P+     +P       K  IV EG+
Sbjct: 3098 DDDGIYKCVAQNLAGKASTRAMLDV---IARDFG-PEFDEEESP-------KPVIVNEGE 3146

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
              +    + G+P   V+W+K  K +  S+   +    + + L I    PEDEG YKCVA 
Sbjct: 3147 EAQMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVAS 3206

Query: 4699 NSAGRV--TVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            ++ GR   T    +KV +P    +LPA  + LR +   EG+  +F   ++ +  PT++W 
Sbjct: 3207 STNGRSSRTFDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWF 3266

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNT 4783
            ++   I     F+   +G   +L+   T
Sbjct: 3267 KDDTPIKHEDRFRTYFDGRVCMLVFRKT 3294



 Score =  147 bits (356), Expect = 2e-34
 Identities = 101/405 (24%), Positives = 174/405 (42%), Gaps = 19/405 (4%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P+ T+K++  +  E    RFE+     P P ++WYR +  + + P +QI        L I
Sbjct: 5052 PVITRKIRDAQGEEGSNIRFEIHVKSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTI 5111

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTSGQ 4529
              V  +D+  +  VA N+ G++   A +VV++K       + P    +TA   + +T G 
Sbjct: 5112 TGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDKP------LAPKVAEMTATGPITITRGN 5165

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             + L+  + G     V W K+G K+      +I      Y L+IL    + +G Y C A 
Sbjct: 5166 QLNLNVTIRGKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEAT 5225

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            +  G      +  +  P          +AA   P  ++ L  +   EG  ++FSCK+ G 
Sbjct: 5226 SKLGNTSAKFDVQIQAP----------EAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGY 5275

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P P ++W +    ++  +        +  TL I  A   D G YKC   N++G  + +A+
Sbjct: 5276 PEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAE 5335

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            L V    Q   L     ++++    G  A+F+  + +  KP I W ++   +     + M
Sbjct: 5336 LVVGGKTQRPRLS--DNMKELFATVGGEARFEVTMKATPKPKICWYKDEITLRSRDRYTM 5393

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
              E     L+I      D+GT+   A+  AG+      L V  KT
Sbjct: 5394 KEEDGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKT 5438



 Score =  147 bits (355), Expect = 3e-34
 Identities = 111/417 (26%), Positives = 182/417 (43%), Gaps = 29/417 (6%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            +E P    + P FT  ++P  V E E   F       P P + WYR    I   PD +  
Sbjct: 1893 IEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWYRNKNEIV--PDGRSR 1950

Query: 4461 T-FSTKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL 4518
            T F  ++  LI++ + ++D+  +  +A N  G A C+A + V ++        V P    
Sbjct: 1951 TTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKRE-------VKPVIKE 2003

Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP 4578
             ++   V+ G    ++ KV+G     V W     +V    R ++ +E   +TL I +   
Sbjct: 2004 VSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGD 2063

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA--E 4636
            Q +  Y+CVA N+AG     A+ V+            T+   AP    E   +K +A  E
Sbjct: 2064 QAAASYKCVAFNNAGRTTYRADLVI------------TEREYAPE--FEDFDEKRIAVRE 2109

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            GQ    +  I  +P P V+WYKGD L+   +   +      Y L I +A  +D G Y C 
Sbjct: 2110 GQNAITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICK 2169

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
            A NS G  +    + V    +A     ++ LR + V EG    +  ++    +PT++W R
Sbjct: 2170 ATNSIGSTSRRIIVDVEALKEAPVF--VSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYR 2227

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +   +     ++M  +G    L +     +D G + C  T +AG   +SA+L V  K
Sbjct: 2228 DNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKK 2284



 Score =  144 bits (348), Expect = 2e-33
 Identities = 126/538 (23%), Positives = 225/538 (41%), Gaps = 40/538 (7%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P      K  +  +G   KF   + G P PV+SW +   P+    +    ++  T   +L
Sbjct: 185 PTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDGTTS--TL 242

Query: 132 LIKQIGPGDEGEYTCTARNQYGE--AICSVYIQPEGXXXXXXXXXXXXXYRHVSETV-EH 188
           LIK +   D+G Y     N  G   +   + + P+                  S+   E 
Sbjct: 243 LIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAFFEV 302

Query: 189 KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLR--EVSFRESITKRYVG 246
           K  G      E    ++K+  ++    ++ D  +  +     LR  +    + I     G
Sbjct: 303 KFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAG 362

Query: 247 ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
           E +++   ++     P +P          +++E      ++ ++GNP+P VTW+K+G +L
Sbjct: 363 ECNLRADLKVKNK--PFAPEFADGDLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQL 420

Query: 307 INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGC----------------IVTS 350
            ++ K ++  T +   L +     +D G Y   A NP G                 ++ S
Sbjct: 421 HDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIES 480

Query: 351 GYLAVESPTESYVQ-------DQRSQY---ITDTQQRETE-ERIEISEKALAPQFVKVCQ 399
           G + ++   E+  +       D   +Y   +T+     T    I + +  + P+F++  +
Sbjct: 481 GLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVE 540

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLS 458
           D    E +   F+  + G P P V W+    +I+D     I  +E  + ++L+I      
Sbjct: 541 DVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTE 600

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           DSG   CVA N +G+T     L+V EK  VV P+F +    + V+ GE    +    G P
Sbjct: 601 DSGPYKCVASNDAGKTTALLNLDVNEK--VVQPEFDKEVKPIEVKHGEEATTSLEIKGKP 658

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
            P++TW KD VP++    +++ + G   TL+I  A   D   Y+C A N AG TA R+
Sbjct: 659 KPKVTWYKDLVPLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAG-TAFRS 715



 Score =  142 bits (343), Expect = 8e-33
 Identities = 151/643 (23%), Positives = 250/643 (38%), Gaps = 55/643 (8%)

Query: 95   LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
            + G P+P VSW R    L++  K+ +R    T      +  +  GD G Y C A+N+ G 
Sbjct: 1827 INGKPSPDVSWYRDDRLLLDGRKHELRKRGNT--YRFTVFNVSAGDAGSYRCEAKNRVGS 1884

Query: 155  AICSVYIQPEGXXXXXXXXXXXXXYR--HVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
            A  +  ++ E               +   V+E   H          E S    +      
Sbjct: 1885 ATRNFNVEIEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWYRNKNEIV 1944

Query: 213  TDHSSTDDFKVDTFEYRL----LREVSFRESITKRYVGESDVQISTEID-RSLGPVSPPK 267
             D  S   F  +T++  L    +++    E I    +G++       ++ R + PV    
Sbjct: 1945 PDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREVKPV---- 2000

Query: 268  IAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRN 327
            I +  +  ++ EG  A  +V++SG P P V W+    R+++ ++ ++             
Sbjct: 2001 IKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQV------------- 2047

Query: 328  TQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISE 387
            TQ+ D   Y  L+    G    + Y  V     ++    R+ Y  D         + I+E
Sbjct: 2048 TQEGD---YHTLSIRDVGDQAAASYKCV-----AFNNAGRTTYRAD---------LVITE 2090

Query: 388  KALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI-LVNES 445
            +  AP+F    + R  V EG+    +  +  RP P+V W+  D  +  D   KI L    
Sbjct: 2091 REYAPEFEDFDEKRIAVREGQNAITNMTIRARPSPDVEWYKGDTLLMSD--RKIDLKTIG 2148

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
            G + L I   TL D+G   C A N  G T+ +  ++V   ++  AP FV +   L V EG
Sbjct: 2149 GLYYLEIRKATLDDAGTYICKATNSIGSTSRRIIVDVEALKE--APVFVSKLRPLFVTEG 2206

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
            + V    +  G P P + W +D  P+  +   ++  DG   +L +  A   D   Y C  
Sbjct: 2207 DNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVI 2266

Query: 566  QNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLRHVERARPYI 625
             N AGS  + A L            ++++  +  +                 V   R  I
Sbjct: 2267 TNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSI 2326

Query: 626  PPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF 685
                E + Y   +   P   V   E   I+F+ R+   G P   I W K+G+ +    RF
Sbjct: 2327 KVRNE-KFYGDDELKEP---VVVQESDAINFKVRVR--GKPVPTIVWYKDGEMVRDVRRF 2380

Query: 686  TSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
                R    +    S + +D+G YTC A +  G       LHV
Sbjct: 2381 EIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHV 2423



 Score =  138 bits (334), Expect = 1e-31
 Identities = 97/395 (24%), Positives = 162/395 (41%), Gaps = 17/395 (4%)

Query: 4419 PCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDS 4478
            P  +    Q    V   G+P P + WY++   I  S + QI +      LII     E +
Sbjct: 5158 PITITRGNQLNLNVTIRGKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHA 5217

Query: 4479 AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT 4538
              ++  A ++ G      ++ ++      +     P+F       N   G +V+   KVT
Sbjct: 5218 GTYSCEATSKLGNTSAKFDVQIQAPEAAPKA----PAFLKQLLPQNAREGDVVKFSCKVT 5273

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
            G    ++ W ++G  ++ D R     +    TL I  A   DSG Y+C   N++G A   
Sbjct: 5274 GYPEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSS 5333

Query: 4599 AECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            AE VV         K Q       P + + +K+     G    F   +   P P + WYK
Sbjct: 5334 AELVVG-------GKTQR------PRLSDNMKELFATVGGEARFEVTMKATPKPKICWYK 5380

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718
             +  ++    + M      YTL I E    D G YK VA N AG+ T    L+V +   A
Sbjct: 5381 DEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKTVA 5440

Query: 4719 DNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778
               P    L  +V  EG+  +  T +    +P+++W +EG L+  +    +   G+   +
Sbjct: 5441 PEFPDRETLEQVVGVEGREVELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYV 5500

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             I +   E +G + C AT + G       L ++++
Sbjct: 5501 WIPSAKHEHSGRYRCEATNSNGTAHRDFVLNIQAQ 5535



 Score =  137 bits (331), Expect = 2e-31
 Identities = 94/368 (25%), Positives = 160/368 (43%), Gaps = 22/368 (5%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G+P P I W ++   ++N+   QI  +     L++ +V  ED+ ++   A+N  G     
Sbjct: 947  GKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKD 1006

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              + VE  +++G      P+F    + + +T G   +L   VTG    +V W ++   ++
Sbjct: 1007 VTITVEALQKKGD----TPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIK 1062

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            P  R K   +     L + EA   D G Y+CV  N+ G     A+  V     +      
Sbjct: 1063 PSRRFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLR------ 1116

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675
                   PE+++ + D    EG    F+ KI   P P ++WY G   I     F++    
Sbjct: 1117 -------PEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTDK 1169

Query: 4676 DE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
            +   Y L I +   +D G  KC A N+AG+  V A L+V + + A +         + V 
Sbjct: 1170 ENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKNVAPSFHGRQ--GRLRVK 1227

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALI-PETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
            EG+ A    +I+ K KP++ W ++  +I  E  +  +   G++    I     ED GT+ 
Sbjct: 1228 EGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYK 1287

Query: 4793 CRATTAAG 4800
            C A    G
Sbjct: 1288 CEARNDVG 1295



 Score =  134 bits (324), Expect = 2e-30
 Identities = 103/407 (25%), Positives = 170/407 (41%), Gaps = 22/407 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P   +++Q   V E +  R   +  G P P ++W + N  + ++  F+         L I
Sbjct: 1315 PEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTI 1374

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            R V + D+  +  V  N  G    SA L V  K          P      ++V    G  
Sbjct: 1375 RNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK-------CTKPEVLEKMKDVKGVEGDE 1427

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
               + K++G    D+ W     +++   R K   +D  Y+L I +   QD G Y+C+A N
Sbjct: 1428 ATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASN 1487

Query: 4591 SAGEARCDAECVVSLPATKD-KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
             AG+    AE  V     +D  P  + K      + +EPL+ ++    Q +E S  + G+
Sbjct: 1488 EAGKVTQRAELEVK---ERDYAPIFEEK------QFLEPLEIQV---RQPVEVSYHVRGR 1535

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P PTV W+K  K ++  K+ ++      +TL I  +  ED G YKC+A N  G      +
Sbjct: 1536 PKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFE 1595

Query: 4710 LKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ 4768
            ++V      +  P LT  LR   + E    +    +     P+ +WL++   +       
Sbjct: 1596 VQVEGVKPKEEAPKLTSQLRSARITESDDFELACDVKGTPDPSYEWLKDDKPVKFDRHLS 1655

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL-VVKSKT 4814
               +G    L        D G++T     A G   +SA L +VKSK+
Sbjct: 1656 SSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKS 1702



 Score =  134 bits (323), Expect = 2e-30
 Identities = 102/406 (25%), Positives = 167/406 (41%), Gaps = 21/406 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F   +    V E + A+   +  G+P P ++W++++  I N+   +         LI 
Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTLIF 3746

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
              V ++D   +   A N+ G+   SA +VV           + P      ++V+   G  
Sbjct: 3747 ETVNIQDRGAYRCTATNQEGSTSSSAVIVVNR-------ASITPRIIEKPRDVDAVDGTD 3799

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
             +   +V G     V W     K+    R +I      Y+L+I        G Y+C+A N
Sbjct: 3800 AKFTVRVEGFPQPKVTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTYKCIATN 3859

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
             AG  +  A C   L  TK    P    +  P    EP+   +V EG  +     + GKP
Sbjct: 3860 DAG--KVTAHC--HLDVTKQDFAPIVAGSEMP----EPI---VVREGCEVSMMANVRGKP 3908

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             PTV+W+K  +L+  +    +    + + L + +    D G YK VA N  G       L
Sbjct: 3909 APTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNL 3968

Query: 4711 KVT--QPDQADNLPA-LTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF 4767
             VT   P +  + P  +T L  + V EG   +F   ++    P+IQW ++   I      
Sbjct: 3969 NVTAIAPKEKWSSPIFVTELSPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRI 4028

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +   +G+   LLIG    ED G +       +G   +SAKL V+ +
Sbjct: 4029 RTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREE 4074



 Score =  133 bits (322), Expect = 3e-30
 Identities = 103/417 (24%), Positives = 167/417 (40%), Gaps = 24/417 (5%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            VE   K    P F  K++P  + E +  +      G P P ++W+R+   IK S  F+  
Sbjct: 1011 VEALQKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKAS 1070

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                 S L +++  ++D  V+  V  N  G+    A++ V +K        + P      
Sbjct: 1071 YDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH-------LRPEVLQKM 1123

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL--EEDGTYTLLILEAYP 4578
             +V    G       K+      ++ W     K+    R KI   +E+ +Y L I +   
Sbjct: 1124 DDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKL 1183

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
             D+G  +C A N+AG+    A+              + +  N  P          V EG+
Sbjct: 1184 DDAGTVKCSATNAAGKTVVRADL-------------EVEEKNVAPSFHGRQGRLRVKEGR 1230

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLI-KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
                  +I GKP P+V WYK D +I    +   +      Y   I +A PED+G YKC A
Sbjct: 1231 EASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEA 1290

Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
             N  G       + V    +    P +   L+   V EG   +   +++   +PT++WL+
Sbjct: 1291 RNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEWLK 1350

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               L+ +   F+   +G    L I N    D   +       AG+V +SAKL V  K
Sbjct: 1351 NNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK 1407



 Score =  133 bits (322), Expect = 3e-30
 Identities = 100/384 (26%), Positives = 163/384 (42%), Gaps = 19/384 (4%)

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477
            Q   V E ++   +V    +P   + WY++   ++++    I +      L+I     ED
Sbjct: 3595 QELNVPEGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPED 3654

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            S ++     +  GT+  + ++    K     G  V P F     +++V  G   +L  K+
Sbjct: 3655 SGLYKCEGVSTLGTSSKTFDV----KAGVPDGSRVTPKFLSHLNSLDVDEGDSAKLTCKM 3710

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
             G     V W K+ + +  + R +      T TL+      QD G Y C A N  G    
Sbjct: 3711 FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSS 3770

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             A  VV+              A+  P IIE  +D    +G   +F+ ++ G P P V W+
Sbjct: 3771 SAVIVVN-------------RASITPRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWF 3817

Query: 4658 -KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
             +  K++   +Y ++SR  D Y+L I        G YKC+A N AG+VT    L VT+ D
Sbjct: 3818 HESTKIVSRGRY-EISRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQD 3876

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
             A  +        IVV EG        +  K  PT++W ++G L+  T +  +   G   
Sbjct: 3877 FAPIVAGSEMPEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYF 3936

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAG 4800
             L +  T + D+GT+   AT   G
Sbjct: 3937 NLDLLKTTQADSGTYKFVATNDLG 3960



 Score =  133 bits (321), Expect = 4e-30
 Identities = 105/411 (25%), Positives = 177/411 (43%), Gaps = 22/411 (5%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K +KP +  +KM+  +  E ++A F V+  G P P I+WY     I++   ++      K
Sbjct: 1407 KCTKPEVL-EKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQK 1465

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNV 4525
              L I+ + ++D   +  +A N  G     A L V+E+       I      L    + V
Sbjct: 1466 YSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKER---DYAPIFEEKQFLEPLEIQV 1522

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY-TLLILEAYPQDSGKY 4584
               Q V +   V G     V W KNGK+++ D ++  +   GTY TL IL +  +D+G Y
Sbjct: 1523 R--QPVEVSYHVRGRPKPTVTWWKNGKELR-DGKHVEIRSGGTYHTLYILRSEEEDAGSY 1579

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
            +C+A N  G     AE +  +     KPK +       P++   L+   + E    E +C
Sbjct: 1580 KCLARNDVG----SAERLFEVQVEGVKPKEEA------PKLTSQLRSARITESDDFELAC 1629

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             + G P P+ +W K DK +K  ++   S    + TL        D+G Y     N+ G  
Sbjct: 1630 DVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGST 1689

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
              +A L + +      +  L  ++D    E   A+F  +I +  K  ++W    A I + 
Sbjct: 1690 YSSANLDIVKSKSKPEI--LETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDG 1747

Query: 4765 PDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
              + +  +  +    + I +   ED GT+   A    G+    A+L VK K
Sbjct: 1748 GRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798



 Score =  133 bits (321), Expect = 4e-30
 Identities = 111/431 (25%), Positives = 180/431 (41%), Gaps = 26/431 (6%)

Query: 4387 TTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYR 4446
            T+E E  +Q  +  +E   K +  P F   ++   V E E A F  E  G P P I+W+ 
Sbjct: 4431 TSEKETTSQLFDIHIEDVCKSALAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFM 4490

Query: 4447 ENFPIKNSPDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKR 4504
             + P+  S D +I T S   +  L I +  ++D+ V+  +A N  G+A  +A+L V   R
Sbjct: 4491 NDQPV--SRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCR 4548

Query: 4505 RQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE 4564
                   + P+F    + V    G       +V G     + W K+  ++    R  I E
Sbjct: 4549 -------MKPTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISE 4601

Query: 4565 EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-KPQTKAANAPP 4623
            E   Y L I      DSG Y C+  N+ G+  C ++ VV   A +  P  P+ +   A P
Sbjct: 4602 EGDLYNLTIENVGRDDSGTYMCILSNAVGKETCRSQLVVE--AEEFAPFFPEDEGQGAVP 4659

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK-LIKPSKYFQMSRTADEYTLRI 4682
                     +  +   +E    + G P P V WYK D+ +   +    +    + Y LR 
Sbjct: 4660 --------VVTRQDSEVELGAVVRGSPKPEVAWYKDDEDVATDADGLDVGSRDNVYFLRF 4711

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT--QPDQADNLPA-LTPLRDIVVYEGQPAQ 4739
            +    +D G YKCVA N  G  ++   L V    P++  + P+ +  L    V EG+   
Sbjct: 4712 ARPSVKDGGLYKCVATNEHGEASMLFNLDVEGHVPEEDWSAPSFVIELTPTTVTEGESTA 4771

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
             + +IT    P ++W +    +      +   +G    L++  T  ED G + C      
Sbjct: 4772 LEVEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDL 4831

Query: 4800 GQVETSAKLVV 4810
            G   + A L V
Sbjct: 4832 GTASSMADLSV 4842



 Score =  132 bits (320), Expect = 5e-30
 Identities = 90/382 (23%), Positives = 165/382 (43%), Gaps = 15/382 (3%)

Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFA 4482
            FE  +AR E    G P P ++W+  +  + +   +++        L+I  + +ED+  + 
Sbjct: 3297 FECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYK 3356

Query: 4483 AVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLT--AQNVNVTSGQLVRLDTKVTGT 4540
             +A N  G+     +L V+E+       +  P F       N    +G  V +   + G 
Sbjct: 3357 IIATNEHGSTGSVVDLTVKER-------LFGPEFLEEEGVWNKVAKAGGFVNISFTLKGN 3409

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
                V W ++G  +    R  I      + + I     +D+G Y C A +  G A     
Sbjct: 3410 PRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRSCT 3469

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
              + +P+     + +   A     I +   D    EG  ++F  +I G P P V+WY+G 
Sbjct: 3470 LEIKVPSMGGPEEKKISKAL----IGQGDNDVQAVEGWKVQFQTRITGYPYPHVEWYRGT 3525

Query: 4661 KLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718
              +  S  +++++T ++  Y+L +++   +D G YKC+A NSAG       L V     A
Sbjct: 3526 IKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDVKDKQYA 3585

Query: 4719 DNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778
              +P     +++ V EGQ       I SK +  + W ++G L+ +T    +   G++  L
Sbjct: 3586 PEIPGHEDRQELNVPEGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYL 3645

Query: 4779 LIGNTYEEDTGTFTCRATTAAG 4800
            +I +   ED+G + C   +  G
Sbjct: 3646 VIPSAAPEDSGLYKCEGVSTLG 3667



 Score =  132 bits (320), Expect = 5e-30
 Identities = 115/424 (27%), Positives = 188/424 (44%), Gaps = 31/424 (7%)

Query: 4401 VEG--PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ 4458
            VEG  P +    P F  ++ P  V E E    EVE  G PLP ++W++ + P+K+    +
Sbjct: 4741 VEGHVPEEDWSAPSFVIELTPTTVTEGESTALEVEITGTPLPKVEWFKNDKPVKHDHLVR 4800

Query: 4459 IHTFSTKSI-LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFT 4517
             + F  K I LI+R+  +ED+ ++     N  GTA   A+L V          +  P   
Sbjct: 4801 SY-FDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNR-------ALTKPEVA 4852

Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577
                +++   G  VRL+    G     V W ++  ++  + R  I E + T TL+I    
Sbjct: 4853 EKMTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCT 4912

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
              D+G Y+ +  N  G        V++L   + +  P+    +   E ++ ++ + VA  
Sbjct: 4913 TNDTGPYKVIGTNECG----IGGAVLNLIIHEREFGPE--FIDEEGEYVKVVRSEGVAN- 4965

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
              I F+ +  G P P V WYK   L+  +         D + L I     ED G Y C A
Sbjct: 4966 --ITFTVR--GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEA 5021

Query: 4698 YNSAGRVTVAAKLKV--TQPDQADN----LPALT-PLRDIVVYEGQPAQFKTQITSKIKP 4750
             +  G+   +  L V     ++ D+     P +T  +RD    EG   +F+  + S   P
Sbjct: 5022 RSKLGKCFRSCILDVQAVPKEEVDHGQIVKPVITRKIRDAQGEEGSNIRFEIHVKSHPPP 5081

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAV-LLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809
             ++W R    +   P +Q I EG+ A  L I    ++DTG++   AT  AG   + A++V
Sbjct: 5082 HVEWYRGSIKLAHGPKYQ-ISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVV 5140

Query: 4810 VKSK 4813
            VK K
Sbjct: 5141 VKDK 5144



 Score =  130 bits (315), Expect = 2e-29
 Identities = 102/344 (29%), Positives = 151/344 (43%), Gaps = 23/344 (6%)

Query: 4389 EIEHKAQTQERVVEGPVK-PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
            E ++K  T  R  +  VK   K P  T +++P +V E EQ +F     G+P P+I WY++
Sbjct: 162  EAKNKIGTSARDFDVNVKVKGKAPTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKD 221

Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQG 4507
              PIK     +     T S L+I+ V  +D   +     N  G+   +A+L V  K  + 
Sbjct: 222  GQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAK- 280

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED- 4566
                  P      +NV    G     + K  G       W  + KK++P  R KI  +D 
Sbjct: 281  ------PEVVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKKIEPSSRFKITTDDT 334

Query: 4567 -GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI 4625
              T +L+I +    DSG Y+C+A N AGE    A+  V     K+KP     A       
Sbjct: 335  EQTSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV-----KNKP----FAPEFADGD 385

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
            +EP++   V E QA+     + G P P V WYK    +  +K  ++  T D + L I +A
Sbjct: 386  LEPIE---VKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKA 442

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA-LTPLR 4728
               DEG Y C A N  G      K+ V     A  + + L PL+
Sbjct: 443  STNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQ 486



 Score =  130 bits (315), Expect = 2e-29
 Identities = 100/419 (23%), Positives = 180/419 (42%), Gaps = 27/419 (6%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            VEG     + P  T +++  R+ E +      +  G P P  +W +++ P+K        
Sbjct: 1598 VEGVKPKEEAPKLTSQLRSARITESDDFELACDVKGTPDPSYEWLKDDKPVKFDRHLSSS 1657

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRRQGRGGIVPPSFTLT 4519
                K  L  ++V + D   +    +N  G+   SANL +V+ K +        P    T
Sbjct: 1658 FDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSK--------PEILET 1709

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL--EEDGTYTLLILEAY 4577
             ++         + D K+      +V W     ++    R  +   EEDGTY++ I +  
Sbjct: 1710 MKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLR 1769

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDK-PKPQTKAANAPPEIIEPLKDKIVAE 4636
             +D G Y+ VA N  G+    AE  V     K+K   P+ +      E   P + K   E
Sbjct: 1770 LEDCGTYKIVAFNDIGKTSERAELTV-----KEKLIAPEFEGR----ETEVPFRAK---E 1817

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
               +E S  I GKP P V WY+ D+L+   +  ++ +  + Y   +      D G Y+C 
Sbjct: 1818 KSDLEVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCE 1877

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
            A N  G  T    +++  P   D  P+  T L+ I V EG+   F  ++ ++ +P++ W 
Sbjct: 1878 AKNRVGSATRNFNVEIEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWY 1937

Query: 4756 R-EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            R +  ++P+    +   +G    L++ +   +D G + C A+   G+   +A++ V  +
Sbjct: 1938 RNKNEIVPDGRS-RTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995



 Score =  130 bits (315), Expect = 2e-29
 Identities = 91/346 (26%), Positives = 151/346 (43%), Gaps = 21/346 (6%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P+  +  +   V E   A  EV+  G P+P ++WY  +  + +   FQ+        L I
Sbjct: 1999 PVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSI 2058

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            R V  + +A +  VA N  G     A+LV+ E+         P       + + V  GQ 
Sbjct: 2059 RDVGDQAAASYKCVAFNNAGRTTYRADLVITERE------YAPEFEDFDEKRIAVREGQN 2112

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
               +  +      DV W K    +  D +  +    G Y L I +A   D+G Y C A N
Sbjct: 2113 AITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATN 2172

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
            S G        +V + A K+ P             +  L+   V EG  + + CK+ G P
Sbjct: 2173 SIGST--SRRIIVDVEALKEAPV-----------FVSKLRPLFVTEGDNVSWMCKVAGMP 2219

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             PTV+WY+ ++ ++    ++M       +L +SEA  +D+G Y CV  NSAG    +A+L
Sbjct: 2220 RPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAEL 2279

Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
            +V +  +A+    +  + D+   EG  A+F  + +   +P + W R
Sbjct: 2280 QVDK--KANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYR 2323



 Score =  130 bits (315), Expect = 2e-29
 Identities = 106/414 (25%), Positives = 175/414 (42%), Gaps = 28/414 (6%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            V+  KP   T KM      E  + + +    G P+P+++W+R    I +   ++      
Sbjct: 4253 VQACKPQ--TSKMANVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMED 4310

Query: 4465 KSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK---RRQGRGGIVPPSFTLT 4519
            + +  LII  V +EDS  + AVA N  G A   A L V+ K   R    GG         
Sbjct: 4311 EGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTVKGKHFARELEEGG--------C 4362

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
               +    GQ+V +   +    P  V W K+G +++   R  +      Y +++  A  +
Sbjct: 4363 HSRLTFRKGQMVSVKA-IVPAHPKQVIWYKDGIRLEDSRRVNLRSVGERYYVVVPSASFE 4421

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            DSG Y+C    S  E       +      K    P  K+A         L+   V E ++
Sbjct: 4422 DSGIYKC-ETTSEKETTSQLFDIHIEDVCKSALAPGFKSA---------LRSLDVTEDES 4471

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
             EF C++ G P P +QW+  D+ +        S     + L I++A  +D G YKC+A N
Sbjct: 4472 AEFRCEVSGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVN 4531

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA 4759
              G  T  A L V+          +  LR++    G  A F  ++    +P I W ++  
Sbjct: 4532 DNGSATSTADLNVSHCRMKPTF--VERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDIT 4589

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +     F +  EG+   L I N   +D+GT+ C  + A G+    ++LVV+++
Sbjct: 4590 RLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAE 4643



 Score =  129 bits (311), Expect = 6e-29
 Identities = 112/486 (23%), Positives = 198/486 (40%), Gaps = 42/486 (8%)

Query: 91   FEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARN 150
            FE  ++G P P+V W R    + +  ++++  +E+    SL+I +    D G Y C A N
Sbjct: 552  FEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASN 611

Query: 151  QYGE--AICSVYIQPEGXXXXXXXXXXXXXYRHVSE-TVEHKAYGTQGYTTEQSRQTQKV 207
              G+  A+ ++ +  +               +H  E T   +  G         +    +
Sbjct: 612  DAGKTTALLNLDVNEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDLVPL 671

Query: 208  AYTNGTDHSST-DDFKVDTFEYRLLREVSFR-ESITKRYVGESDVQISTEIDRSLGPVSP 265
              T      S  D+  ++        E  ++ E+  K         I  ++    G    
Sbjct: 672  LETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVKVAEPQGET-- 729

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I  +  + +  +G D +    ++G P P V WFK+G+ L  +++           L  
Sbjct: 730  PTITTEMTDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSF 789

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
            R  +  D G Y         C++++ + +V S  E                      +++
Sbjct: 790  RPIKLEDMGRYK--------CVISNVFGSVSSAAE----------------------VKV 819

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
             +++L P+ +   +D D  E +   F C  +G+P PE+ WF     I      +  V E 
Sbjct: 820  EDRSLKPEVITSMRDCDCVEEETASFHCEFSGKPEPEIEWFCGPNPIVP--GGRFHVTEE 877

Query: 446  GN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
            GN  +L I+++ L D+G   CVA N +G+T  +  L V EK    AP+F +   T++  +
Sbjct: 878  GNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEKH--FAPEFEDWKDTIDALD 935

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            G+ V ++    G P P I W KDG  +     ++I   G    L + +    DA  Y C 
Sbjct: 936  GQDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCR 995

Query: 565  AQNVAG 570
            A+N AG
Sbjct: 996  AKNNAG 1001



 Score =  129 bits (311), Expect = 6e-29
 Identities = 114/503 (22%), Positives = 211/503 (41%), Gaps = 41/503 (8%)

Query: 76   QIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQ 135
            Q   + R  +GG A F  K+   P P + W      + +  ++ ++ +++     L I  
Sbjct: 1121 QKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDD 1180

Query: 136  IGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQG 195
            +   D G   C+A N  G+ +    ++ E               R V E  E   Y    
Sbjct: 1181 VKLDDAGTVKCSATNAAGKTVVRADLEVEEKNVAPSFHGRQGRLR-VKEGREASVYFEIS 1239

Query: 196  YTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTE 255
               + S    K     G +  + D +   +  Y  +++    +  T +    +DV  + E
Sbjct: 1240 GKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFE 1299

Query: 256  -----IDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
                 ++     +  P+I Q+ +   + EG D +   ++SG P P + W KN        
Sbjct: 1300 TFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEWLKN-------- 1351

Query: 311  KHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQY 370
             +E+++ ++    R       D    TL   N     VT   LA   P +  V++     
Sbjct: 1352 -NELLSDNDRFKTRF------DGQTGTLTIRN-----VT---LADAVPYKVVVRN----- 1391

Query: 371  ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430
              D  +  +  ++++  K   P+ ++  +D    EG    F+ +++G P P++ W+    
Sbjct: 1392 --DAGEVSSSAKLKVIRKCTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTT 1449

Query: 431  QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490
            +IRD   +K   ++   ++L I ++ L D G   C+A N++G+   +  L V  KE+  A
Sbjct: 1450 RIRDGGRYKFSRDDQ-KYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEV--KERDYA 1506

Query: 491  PKFVER--FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
            P F E+     L ++  +PV ++    G P P +TW K+G  +     + I + G   TL
Sbjct: 1507 PIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTL 1566

Query: 549  DIPRAKASDAAWYQCTAQNVAGS 571
             I R++  DA  Y+C A+N  GS
Sbjct: 1567 YILRSEEEDAGSYKCLARNDVGS 1589



 Score =  128 bits (309), Expect = 1e-28
 Identities = 107/390 (27%), Positives = 158/390 (40%), Gaps = 20/390 (5%)

Query: 4427 QARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAE 4486
            +ARFEV     P P I WY++   +++   + +        LII++V + DS  +  VA 
Sbjct: 5361 EARFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVAS 5420

Query: 4487 NRGGTAKCSANLVVEEKRRQGRGGIVPPSFT--LTAQNVNVTSGQLVRLDTKVTGTKPID 4544
            N+ G       L V EK        V P F    T + V    G+ V L T V G     
Sbjct: 5421 NKAGKTTFLGYLEVMEKT-------VAPEFPDRETLEQVVGVEGREVELSTVVKGLPRPS 5473

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS 4604
            V W K GK +       +     T+ + I  A  + SG+Y C A NS G A  D   V++
Sbjct: 5474 VKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEATNSNGTAHRD--FVLN 5531

Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
            + A    P  Q  A    P    PL+   + EG    F  +I G P+P V+WY+ D+ + 
Sbjct: 5532 IQA--QVPAEQWVA----PAFTAPLQHIDILEGDTTRFIGEITGVPVPVVEWYRDDRPVT 5585

Query: 4665 PSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
                 +         L + +    D G +KCV  N  G V  +A L V +      +   
Sbjct: 5586 RDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNEGYSKPEIN-- 5643

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDF-QMIHEGNNAVLLIGNT 4783
              L+ I  +EG  A+F   +T    P + W R    I +   +   +     A L I   
Sbjct: 5644 EKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKI 5703

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +ED G + C A    G+  +   L V  K
Sbjct: 5704 RQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733



 Score =  124 bits (300), Expect = 1e-27
 Identities = 121/505 (23%), Positives = 208/505 (41%), Gaps = 42/505 (8%)

Query: 82   RFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDE 141
            R  +G  A    ++ G P P V+W +    + + ++    Y+  +      IKQ  P D+
Sbjct: 1225 RVKEGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSS-YYFTIKQARPEDK 1283

Query: 142  GEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGT---QGYTT 198
            G Y C ARN  G A  +  I  E               +    T       T    GY  
Sbjct: 1284 GTYKCEARNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPE 1343

Query: 199  EQSRQTQKVAYTNGTDHSSTD-DFKVDTFEYRLLREVSFRESITKRYVGESDV-QISTEI 256
                  +     +  D   T  D +  T     +R V+  +++  + V  +D  ++S+  
Sbjct: 1344 PTLEWLKNNELLSDNDRFKTRFDGQTGTLT---IRNVTLADAVPYKVVVRNDAGEVSSSA 1400

Query: 257  D-RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEII 315
              + +   + P++ +K ++ K  EG +A F V+LSG P P + W+    R+ +  +++  
Sbjct: 1401 KLKVIRKCTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFS 1460

Query: 316  TTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQ 375
                  +L +++    D G Y  +A N  G +                  QR++   + +
Sbjct: 1461 RDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVT-----------------QRAEL--EVK 1501

Query: 376  QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
            +R+     E  ++ L P  ++V Q  +V+          V GRP P VTW+ N +++RD 
Sbjct: 1502 ERDYAPIFE-EKQFLEPLEIQVRQPVEVSY--------HVRGRPKPTVTWWKNGKELRDG 1552

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG--ETAFQCRLNVIEKEQVVAPKF 493
              H  + +    H L I      D+G   C+ARN  G  E  F+ ++  ++ ++  APK 
Sbjct: 1553 -KHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVEGVKPKEE-APKL 1610

Query: 494  VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRA 553
              +  +  + E +   L     GTP P   W KD  P+  +  L    DG   TL+  R 
Sbjct: 1611 TSQLRSARITESDDFELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRV 1670

Query: 554  KASDAAWYQCTAQNVAGSTATRARL 578
            + SD   Y  T +N  GST + A L
Sbjct: 1671 QLSDQGSYTVTFKNAHGSTYSSANL 1695



 Score =  124 bits (300), Expect = 1e-27
 Identities = 100/389 (25%), Positives = 166/389 (42%), Gaps = 26/389 (6%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + WY++   + ++    + +        I  V  ED+  +   A NR G++  S
Sbjct: 2654 GNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRS 2713

Query: 4496 ANLVVEEKRR------QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549
              + ++E +       +  G ++P       + V    G   R D  V  +  ID+ W +
Sbjct: 2714 CTIEIKEPKSVDSTDTRAPGQLIPVKHKFDFEGV---PGGKARCDVLVKKSDIIDIEWFR 2770

Query: 4550 NGKKVQPDIRNKILEEDGTYTL-LILE-AYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
                ++   + KIL+ D   TL LI+E    +D+G Y CV    AG+     E  +    
Sbjct: 2771 GTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHI---- 2826

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDK--IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
               K K Q     AP  + E +  +   + +GQ +  S  + G P P + WYK  + +  
Sbjct: 2827 ---KEKQQ-----APLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDD 2878

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            ++   +    + Y L I    PED G Y C A N  G    + ++ VT P      P+ +
Sbjct: 2879 TRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPKVKGEAPSFS 2938

Query: 4726 -PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
              LR I   E   ++    ++ K KP I+W + G  +      +  ++G  A L I    
Sbjct: 2939 LELRPIAAIEEFDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIVAYLSIWQVS 2998

Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +D GT+ C A+ AAG V +SA L V  +
Sbjct: 2999 HDDAGTYECIASNAAGTVSSSAALTVSRR 3027



 Score =  124 bits (300), Expect = 1e-27
 Identities = 121/497 (24%), Positives = 193/497 (38%), Gaps = 29/497 (5%)

Query: 4316 KSMAQRYEDNLDQTEEVT--EQR--VQKKVTQKPRIP-DPSESTVHGKEVHVAKQKQTQK 4370
            K+   R  DN+ +       E R  V  K T KP+I     E T+  ++ +  K++    
Sbjct: 5341 KTQRPRLSDNMKELFATVGGEARFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIY 5400

Query: 4371 EVVGDKEITRKITSTETTEIEHKAQTQE-----RVVEGPVKPSKPPIFTKKMQPCRVFEH 4425
             ++  KE+    + T      +KA          V+E  V P  P   T  ++     E 
Sbjct: 5401 TLI-IKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKTVAPEFPDRET--LEQVVGVEG 5457

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVA 4485
             +        G P P +KWY+E   +  S    + T      + I     E S  +   A
Sbjct: 5458 REVELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEA 5517

Query: 4486 ENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDV 4545
             N  GTA    + V+  + +      V P+FT   Q++++  G   R   ++TG     V
Sbjct: 5518 TNSNGTAH--RDFVLNIQAQVPAEQWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVPVV 5575

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W ++ + V  D R +   +     LL+ +    D+G ++CV  N  G     A   V+ 
Sbjct: 5576 EWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNE 5635

Query: 4606 PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
              +K             PEI E LK     EG    F   + G P P V WY+G   I  
Sbjct: 5636 GYSK-------------PEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITD 5682

Query: 4666 SKYFQMSRTADEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL 4724
               +  + T+D   +L I +   ED G Y CVA N  G  T    L V +          
Sbjct: 5683 CNRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEKHYGPEFAEE 5742

Query: 4725 TPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
                     +G+ A+    ++   +P + W ++G L+ +T    M   G+   L I    
Sbjct: 5743 ELDWSKTARKGENARITFTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLT 5802

Query: 4785 EEDTGTFTCRATTAAGQ 4801
             +DTGT+ C A +  G+
Sbjct: 5803 HDDTGTYVCEAQSRLGK 5819



 Score =  124 bits (298), Expect = 2e-27
 Identities = 124/506 (24%), Positives = 202/506 (39%), Gaps = 49/506 (9%)

Query: 87   GNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTC 146
            G A     + GNP P V W +    L E ++  MR  +    +++    + P D G Y C
Sbjct: 4168 GFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIF--GLTPDDAGTYVC 4225

Query: 147  TARNQYGEAI--CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204
             AR++ G     C++ ++                   ++     + +  Q  T       
Sbjct: 4226 EARSRLGTCFRSCTLDVKAVRPRRGNEVQACKPQTSKMANVTAVEGWKVQLDTRMTGYPV 4285

Query: 205  QKVAYTNGTDHSSTDD--FKVDTFE----YRLL-REVSFRESITKRYVGESDVQISTEID 257
              V +  G +   TD   +K    E    Y L+  +V   +S + R V  +++  +T + 
Sbjct: 4286 PIVEWFRG-EEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLA 4344

Query: 258  RSL--GPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE 313
                 G     ++ +   +S+L  ++G     +  +  +P+ +V W+K+G RL +S +  
Sbjct: 4345 ELTVKGKHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHPK-QVIWYKDGIRLEDSRRVN 4403

Query: 314  IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
            + +      + V +    DSG Y         C  TS     E  T S + D   +    
Sbjct: 4404 LRSVGERYYVVVPSASFEDSGIYK--------CETTS-----EKETTSQLFDIHIE---- 4446

Query: 374  TQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR 433
                      ++ + ALAP F    +  DVTE +   F C V+G P P + WF+ND+ + 
Sbjct: 4447 ----------DVCKSALAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFMNDQPVS 4496

Query: 434  DDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPK 492
             D   +I+ +  G  H L IT  TL D+GV  C+A N +G       LNV      + P 
Sbjct: 4497 RD--SRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCR--MKPT 4552

Query: 493  FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552
            FVER   +    G     + R  G P P+I W KD   +I      I  +G    L I  
Sbjct: 4553 FVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYNLTIEN 4612

Query: 553  AKASDAAWYQCTAQNVAGSTATRARL 578
                D+  Y C   N  G    R++L
Sbjct: 4613 VGRDDSGTYMCILSNAVGKETCRSQL 4638



 Score =  121 bits (292), Expect = 1e-26
 Identities = 116/510 (22%), Positives = 206/510 (40%), Gaps = 36/510 (7%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F+   +     +GG     G++ G P P + W +   P++  ++   +++ +T  V  
Sbjct: 2433 PSFKSQLQPVILEEGGTGVLVGEVAGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKV-- 2490

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
            + ++   GD G Y C  +NQ GEA     +                    V         
Sbjct: 2491 IFREALIGDGGMYECIIKNQCGEASSKALVGVNRGTVGPEIIEKPAGLVIVEGNDSRFDV 2550

Query: 192  GTQGYTTEQSRQTQ-KVAYTNGTDHSSTDDFKVDTFEYRL----LREVSFRESITKRYVG 246
              +G+ T +          T+G  +    + ++  +   +    L +      +     G
Sbjct: 2551 RIRGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTGHYRIVASNEHG 2610

Query: 247  ESDVQISTEIDRSLGPVSPPKIAQKPRNSKL-QEGADAQFQVQLSGNPRPRVTWFKNGQR 305
            ++   +   ++  L   +P  +      SK+ ++G        L GNPRP VTW+K+G  
Sbjct: 2611 KAQALLDLTVNERL--YAPEFLEDDGEWSKVVRKGGFVNITFTLMGNPRPFVTWYKDGIL 2668

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
            L ++++ ++ +  +     +      D+G Y   A N  G    S  + ++ P       
Sbjct: 2669 LYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEIKEP------- 2721

Query: 366  QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
             +S   TDT  R   + I +  K           D +   G   R D  V      ++ W
Sbjct: 2722 -KSVDSTDT--RAPGQLIPVKHKF----------DFEGVPGGKARCDVLVKKSDIIDIEW 2768

Query: 426  FINDRQIRDDYNHKILVNESGNH-ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
            F     +RD   +KIL ++ G   +L++ NV   D+G   CV    +G+T  +  L++ E
Sbjct: 2769 FRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHIKE 2828

Query: 485  KEQVVAPKFV-ERFS--TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
            K+Q  AP F+ E+ S    ++ +G+ +  +    G+PTP ITW KDG P+     + I +
Sbjct: 2829 KQQ--APLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRIDIRS 2886

Query: 542  DGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             G    L I   K  DA  Y C A N  G+
Sbjct: 2887 RGNVYYLGILNLKPEDAGTYTCEAGNRIGA 2916



 Score =  121 bits (292), Expect = 1e-26
 Identities = 132/531 (24%), Positives = 214/531 (40%), Gaps = 52/531 (9%)

Query: 61   ITAGRPGEPSPPIFEQIF-KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYS 119
            I A      +P   +Q+  +NAR  +G   KF  K+ G P P + WTR    +    + +
Sbjct: 5239 IQAPEAAPKAPAFLKQLLPQNAR--EGDVVKFSCKVTGYPEPEIEWTRDGVSMESDERVT 5296

Query: 120  MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXY 179
              Y+ +   +S  I      D G Y CT +N  G A  S  +   G              
Sbjct: 5297 TWYDGEHSTLS--IHNANHADSGMYKCTLKNNSGWASSSAELVVGGKTQRPRLSDNM--- 5351

Query: 180  RHVSETVEHKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKV---DTFEYRLLREVS 235
            + +  TV  +A   +   T ++    K+  Y +     S D + +   D     +++EV 
Sbjct: 5352 KELFATVGGEA---RFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQ 5408

Query: 236  FRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQ-----EGADAQFQVQLS 290
              +S T ++V  +    +T +   L  +      + P    L+     EG + +    + 
Sbjct: 5409 LSDSGTYKFVASNKAGKTTFLGY-LEVMEKTVAPEFPDRETLEQVVGVEGREVELSTVVK 5467

Query: 291  GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
            G PRP V W+K G +L++++K   ++T   T             HY  +   P+     S
Sbjct: 5468 GLPRPSVKWYKEG-KLLHTSKALTVSTSGDT-------------HYVWI---PSAKHEHS 5510

Query: 351  GYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410
            G    E+ T S     R  ++ + Q +        +E+ +AP F    Q  D+ EG  TR
Sbjct: 5511 GRYRCEA-TNSNGTAHRD-FVLNIQAQVP------AEQWVAPAFTAPLQHIDILEGDTTR 5562

Query: 411  FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT-LSDSGVVTCVARN 469
            F   +TG P P V W+ +DR +  D  H++     G   +++   T +SD+GV  CV RN
Sbjct: 5563 FIGEITGVPVPVVEWYRDDRPVTRD--HRLRTYSDGRVVILLLRQTNISDAGVFKCVLRN 5620

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
              G  A    LNV   E    P+  E+   +   EG     +    G P PR+ W +   
Sbjct: 5621 DLGTVASSASLNV--NEGYSKPEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTT 5678

Query: 530  PIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
             I   N      T  G ++L I + +  D   Y C A N  G T +   L+
Sbjct: 5679 KITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLH 5729



 Score =  121 bits (291), Expect = 2e-26
 Identities = 123/537 (22%), Positives = 211/537 (39%), Gaps = 49/537 (9%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-S 130
            P+ +++ K    ++GG A  E K+ G P P V W      +++ +++ +    Q GD  +
Sbjct: 1999 PVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVT---QEGDYHT 2055

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I+ +G      Y C A N  G       +                 +    E      
Sbjct: 2056 LSIRDVGDQAAASYKCVAFNNAGRTTYRADL-------VITEREYAPEFEDFDEKRIAVR 2108

Query: 191  YGTQGYT--TEQSRQTQKVAYTNGTDHSSTDDFKVDT-----FEYRLLREVSFRESITKR 243
             G    T  T ++R +  V +  G D     D K+D        Y  +R+ +  ++ T  
Sbjct: 2109 EGQNAITNMTIRARPSPDVEWYKG-DTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGT-- 2165

Query: 244  YVGESDVQISTEIDRSLGPVSP----PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
            Y+ ++   I +   R +  V      P    K R   + EG +  +  +++G PRP V W
Sbjct: 2166 YICKATNSIGSTSRRIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEW 2225

Query: 300  FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
            +++ Q L    + ++       +L +      D G Y  +  N  G   +S  L V+   
Sbjct: 2226 YRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKA 2285

Query: 360  ESYVQDQRSQYITDTQQRE-TEERIEISEKALA-PQF------VKVCQDRD--------- 402
                + +  + + D Q  E TE R ++    L  P+       +KV  ++          
Sbjct: 2286 N---KPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEP 2342

Query: 403  --VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
              V E     F  RV G+P P + W+ +   +RD    +I  +    +     + +  D+
Sbjct: 2343 VVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIR-SRGDIYTFATYSASAEDA 2401

Query: 461  GVVTCVARNKSGETAFQCRLNV-IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519
            G  TC A NK G+ +    L+V + KEQ  AP F  +   + + EG   VL     G P 
Sbjct: 2402 GTYTCEASNKLGKCSRDFNLHVDVPKEQWEAPSFKSQLQPVILEEGGTGVLVGEVAGKPL 2461

Query: 520  PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
            P I W KD  P++    +R   DG    +    A   D   Y+C  +N  G  +++A
Sbjct: 2462 PTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCGEASSKA 2518



 Score =  121 bits (291), Expect = 2e-26
 Identities = 84/316 (26%), Positives = 136/316 (43%), Gaps = 29/316 (9%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P   ++ R      G +A F V++ G PRP++ W+K+  RLIN  +  I    +   L +
Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYNLTI 4610

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
             N  + DSG Y  +  N  G       L VE+           ++     + E +  + +
Sbjct: 4611 ENVGRDDSGTYMCILSNAVGKETCRSQLVVEA----------EEFAPFFPEDEGQGAVPV 4660

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
              +          QD +V  G + R      G P PEV W+ +D  +  D +   + +  
Sbjct: 4661 VTR----------QDSEVELGAVVR------GSPKPEVAWYKDDEDVATDADGLDVGSRD 4704

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV---IEKEQVVAPKFVERFSTLNV 502
              + L     ++ D G+  CVA N+ GE +    L+V   + +E   AP FV   +   V
Sbjct: 4705 NVYFLRFARPSVKDGGLYKCVATNEHGEASMLFNLDVEGHVPEEDWSAPSFVIELTPTTV 4764

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             EGE   L     GTP P++ W K+  P+  +  +R + DG    L + R    DA  Y+
Sbjct: 4765 TEGESTALEVEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYR 4824

Query: 563  CTAQNVAGSTATRARL 578
            CT  N  G+ ++ A L
Sbjct: 4825 CTILNDLGTASSMADL 4840



 Score =  120 bits (289), Expect = 3e-26
 Identities = 91/345 (26%), Positives = 155/345 (44%), Gaps = 27/345 (7%)

Query: 4475 VEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLD 4534
            ++D+  +     N  G+    A++ V++ +       V P F    ++V     + V  +
Sbjct: 501  LDDAGEYKVKVTNEVGSVTSLADINVQKAK-------VKPEFLRKVEDVTALETEQVWFE 553

Query: 4535 TKVTG-TKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYPQDSGKYECVAINS 4591
              + G  +PI V W +   +++   R  I E  E+  Y+L+I EA  +DSG Y+CVA N 
Sbjct: 554  IPIQGYPRPI-VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASND 612

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
            AG+       +++L   +   +P+      P E         V  G+    S +I GKP 
Sbjct: 613  AGKTTA----LLNLDVNEKVVQPEFDKEVKPIE---------VKHGEEATTSLEIKGKPK 659

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV--TVAAK 4709
            P V WYK    +  ++  Q+    DE+TL I  A P+DEG YKC A N AG    +   K
Sbjct: 660  PKVTWYKDLVPLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIK 719

Query: 4710 LKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQM 4769
            +KV +P Q +     T + DI   +G+  +    +T +  P ++W ++G  +        
Sbjct: 720  VKVAEP-QGETPTITTEMTDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPLKANHRLVP 778

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
              E     L       ED G + C  +   G V ++A++ V+ ++
Sbjct: 779  SFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS 823



 Score =  120 bits (289), Expect = 3e-26
 Identities = 93/379 (24%), Positives = 152/379 (40%), Gaps = 18/379 (4%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIR--QVFVEDSAVFAAVAENRGGTAK 4493
            G P P + WY+++  +    D  +   S  ++  +R  +  V+D  ++  VA N  G A 
Sbjct: 4676 GSPKPEVAWYKDDEDVATDAD-GLDVGSRDNVYFLRFARPSVKDGGLYKCVATNEHGEAS 4734

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
               NL VE    +       PSF +      VT G+   L+ ++TGT    V W KN K 
Sbjct: 4735 MLFNLDVEGHVPEEDWSA--PSFVIELTPTTVTEGESTALEVEITGTPLPKVEWFKNDKP 4792

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            V+ D   +   +     L++     +D+G Y C  +N  G A   A+  V+   TK    
Sbjct: 4793 VKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTK---- 4848

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
                     PE+ E + D    EG  +       G P+P V+W++ +  +  +  + +S 
Sbjct: 4849 ---------PEVAEKMTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISE 4899

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
            T D  TL I      D G YK +  N  G       L + + +              VV 
Sbjct: 4900 TEDTSTLVIRNCTTNDTGPYKVIGTNECGIGGAVLNLIIHEREFGPEFIDEEGEYVKVVR 4959

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
                A     +    +P + W ++G L+ +T        G+   L I +   ED GT+ C
Sbjct: 4960 SEGVANITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMC 5019

Query: 4794 RATTAAGQVETSAKLVVKS 4812
             A +  G+   S  L V++
Sbjct: 5020 EARSKLGKCFRSCILDVQA 5038



 Score =  120 bits (288), Expect = 4e-26
 Identities = 101/421 (23%), Positives = 181/421 (42%), Gaps = 22/421 (5%)

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
           +E++ K   P+ V+  ++ +  EG    F+ +  G P P+  WF + ++I      KI  
Sbjct: 272 LEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKKIEPSSRFKITT 331

Query: 443 NESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER-FSTL 500
           +++    +L+I+++ L DSG   C+A N++GE   +  L V  K +  AP+F +     +
Sbjct: 332 DDTEQTSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV--KNKPFAPEFADGDLEPI 389

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
            V+E + V +     G P P +TW KDG  +    +L++   G    L IP+A  +D   
Sbjct: 390 EVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQ 449

Query: 561 YQCTAQNVAGS-------TATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXX 613
           Y C A N  GS       T     +           Q R        V            
Sbjct: 450 YFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKV 509

Query: 614 YLRHVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL 673
            + +   +   +      +    P+F+  ++ VTA+E  ++ FE  I+  G P   +EW 
Sbjct: 510 KVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPIQ--GYPRPIVEWY 567

Query: 674 KNGQSIEASSRFT--SIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
           +    I+   RFT          SL +     +DSG Y C  V++    +T A+L++   
Sbjct: 568 RGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKC--VASNDAGKTTALLNLDVN 625

Query: 732 ATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFE 791
              E+  Q PE  + ++ +E     +   S+E +   +P+ +   +DL  L E R+   +
Sbjct: 626 ---EKVVQ-PEFDKEVKPIEVKHGEEATTSLEIKGKPKPK-VTWYKDLVPLLETRSIQLK 680

Query: 792 A 792
           +
Sbjct: 681 S 681



 Score =  119 bits (286), Expect = 7e-26
 Identities = 98/428 (22%), Positives = 178/428 (41%), Gaps = 36/428 (8%)

Query: 4401 VEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            V+ P +  + P F  ++QP  + E        E  G+PLP I+W ++++P+      +  
Sbjct: 2423 VDVPKEQWEAPSFKSQLQPVILEEGGTGVLVGEVAGKPLPTIQWMKDDYPVLFGHRVRPQ 2482

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
                   +I R+  + D  ++  + +N+ G A   A + V         G V P      
Sbjct: 2483 FDGRTCKVIFREALIGDGGMYECIIKNQCGEASSKALVGVNR-------GTVGPEIIEKP 2535

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYP 4578
              + +  G   R D ++ G    +V W    +++   ++ +I    E G Y+L++ +   
Sbjct: 2536 AGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQL 2595

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD--KIVAE 4636
              +G Y  VA N  G+A+   +  V+                  PE +E   +  K+V +
Sbjct: 2596 DQTGHYRIVASNEHGKAQALLDLTVN-------------ERLYAPEFLEDDGEWSKVVRK 2642

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G  +  +  ++G P P V WYK   L+  +    M    D     I    PED G Y C 
Sbjct: 2643 GGFVNITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCE 2702

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPA-----LTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            A+N  G    +  +++ +P   D+        L P++    +EG P   K +    +K +
Sbjct: 2703 AHNRLGSSFRSCTIEIKEPKSVDSTDTRAPGQLIPVKHKFDFEGVPGG-KARCDVLVKKS 2761

Query: 4752 ----IQWLREGALIPETPDFQMI--HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
                I+W R   ++ +   ++++   +G    L++ N   ED GT+ C   T AGQ    
Sbjct: 2762 DIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIR 2821

Query: 4806 AKLVVKSK 4813
             +L +K K
Sbjct: 2822 GELHIKEK 2829



 Score =  119 bits (286), Expect = 7e-26
 Identities = 101/395 (25%), Positives = 152/395 (38%), Gaps = 22/395 (5%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F ++++        +A F V   G P P I WY++   + N   F I        L I
Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYNLTI 4610

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
              V  +DS  +  +  N  G   C + LVVE +         P      A  V       
Sbjct: 4611 ENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEE---FAPFFPEDEGQGAVPVVTRQDSE 4667

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRN-KILEEDGTYTLLILEAYPQDSGKYECVAI 4589
            V L   V G+   +V W K+ + V  D     +   D  Y L       +D G Y+CVA 
Sbjct: 4668 VELGAVVRGSPKPEVAWYKDDEDVATDADGLDVGSRDNVYFLRFARPSVKDGGLYKCVAT 4727

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            N  GE    A  + +L      P+      +AP  +IE L    V EG++     +I G 
Sbjct: 4728 NEHGE----ASMLFNLDVEGHVPEEDW---SAPSFVIE-LTPTTVTEGESTALEVEITGT 4779

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            PLP V+W+K DK +K     +         L +     ED G Y+C   N  G  +  A 
Sbjct: 4780 PLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMAD 4839

Query: 4710 LKV----TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
            L V    T+P+ A+       + DI   EG   + +        P ++W R+   +    
Sbjct: 4840 LSVNRALTKPEVAEK------MTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNND 4893

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             + +    + + L+I N    DTG +    T   G
Sbjct: 4894 RYTISETEDTSTLVIRNCTTNDTGPYKVIGTNECG 4928



 Score =  118 bits (284), Expect = 1e-25
 Identities = 89/325 (27%), Positives = 143/325 (44%), Gaps = 36/325 (11%)

Query: 249  DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
            DV I+ E  +  G    P    K    ++ EG D Q    ++G P+P V WF++   +  
Sbjct: 1006 DVTITVEALQKKGDT--PTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKP 1063

Query: 309  SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
            S + +     N + L V+  +  D G Y         C+VT+ + +V S  +        
Sbjct: 1064 SRRFKASYDGNVSALTVKEAELDDDGVYK--------CVVTNNFGSVSSKAD-------- 1107

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
                          + + +K L P+ ++   D    EG    F  ++   P PE+ W++ 
Sbjct: 1108 --------------VTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLG 1153

Query: 429  DRQIRDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
              +I D    KI  + E+ ++ L I +V L D+G V C A N +G+T  +  L V EK  
Sbjct: 1154 ATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKN- 1212

Query: 488  VVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI-IPNPELRIHTDGGAS 546
             VAP F  R   L V+EG    +     G P P +TW KD V I   +  + I++ G + 
Sbjct: 1213 -VAPSFHGRQGRLRVKEGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSY 1271

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGS 571
               I +A+  D   Y+C A+N  G+
Sbjct: 1272 YFTIKQARPEDKGTYKCEARNDVGT 1296



 Score =  118 bits (283), Expect = 2e-25
 Identities = 121/491 (24%), Positives = 191/491 (38%), Gaps = 49/491 (9%)

Query: 4250 RPELKPKVIKEPETEW-QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDK 4308
            R E+  K   +P+  W +  +  +  + Y  K ++     +IKE +L +S     +  +K
Sbjct: 5363 RFEVTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVASNK 5422

Query: 4309 VTSNT-------VAKSMAQRYEDN--LDQTEEVTEQRVQKKVTQKPRIPDPSESTV-HGK 4358
                T       + K++A  + D   L+Q   V  + V+     K  +P PS      GK
Sbjct: 5423 AGKTTFLGYLEVMEKTVAPEFPDRETLEQVVGVEGREVELSTVVKG-LPRPSVKWYKEGK 5481

Query: 4359 EVHVAKQKQTQKEVVGDKEIT------------RKITSTETTEIEHKAQTQERVVEGPVK 4406
             +H +K         GD                 +  +T +    H+        + P +
Sbjct: 5482 LLHTSKALTVSTS--GDTHYVWIPSAKHEHSGRYRCEATNSNGTAHRDFVLNIQAQVPAE 5539

Query: 4407 PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKS 4466
                P FT  +Q   + E +  RF  E  G P+P+++WYR++ P+      + ++     
Sbjct: 5540 QWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVV 5599

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
            IL++RQ  + D+ VF  V  N  GT   SA+L V E       G   P      + +   
Sbjct: 5600 ILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNE-------GYSKPEINEKLKKIEAF 5652

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIR-NKILEEDGTYTLLILEAYPQDSGKYE 4585
             G   R D  VTG  P  V W +   K+    R +  L  DG  +L I +   +D G Y 
Sbjct: 5653 EGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYG 5712

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD--KIVAEGQAIEFS 4643
            CVA+N  GE       +V L              +  PE  E   D  K   +G+    +
Sbjct: 5713 CVAVNEYGE----TTSIVDL---------HVGEKHYGPEFAEEELDWSKTARKGENARIT 5759

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
              + G P P V WYK   L+  + +  M    D   L I     +D G Y C A +  G+
Sbjct: 5760 FTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCEAQSRLGK 5819

Query: 4704 VTVAAKLKVTQ 4714
                  LKV +
Sbjct: 5820 SFRTYALKVEE 5830



 Score =  116 bits (279), Expect = 5e-25
 Identities = 99/396 (25%), Positives = 158/396 (39%), Gaps = 19/396 (4%)

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477
            +P  V E +   F+V   G+P+P I WY++   +++   F+I +              ED
Sbjct: 2341 EPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAED 2400

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            +  +   A N+ G      NL V+  + Q       PSF    Q V +  G    L  +V
Sbjct: 2401 AGTYTCEASNKLGKCSRDFNLHVDVPKEQWEA----PSFKSQLQPVILEEGGTGVLVGEV 2456

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
             G     + W+K+   V    R +   +  T  ++  EA   D G YEC+  N  GEA  
Sbjct: 2457 AGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCGEA-- 2514

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             ++ +V +                 PEIIE     ++ EG    F  +I G P P V+W+
Sbjct: 2515 SSKALVGV-----------NRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWF 2563

Query: 4658 KG-DKLIKPSKY-FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
             G ++L    KY  + +     Y+L +S+   +  G Y+ VA N  G+      L V + 
Sbjct: 2564 YGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER 2623

Query: 4716 DQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNN 4775
              A            VV +G        +    +P + W ++G L+ +T    M   G+ 
Sbjct: 2624 LYAPEFLEDDGEWSKVVRKGGFVNITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDI 2683

Query: 4776 AVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                I     EDTGT+ C A    G    S  + +K
Sbjct: 2684 QYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEIK 2719



 Score =  116 bits (279), Expect = 5e-25
 Identities = 117/514 (22%), Positives = 209/514 (40%), Gaps = 59/514 (11%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G   + E    G P P V W R    L   ++Y++   E T   +L+I+     D G Y
Sbjct: 4862 EGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTS--TLVIRNCTTNDTGPY 4919

Query: 145  TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204
                 N+ G     + +                 Y  V   V  +      +T   + + 
Sbjct: 4920 KVIGTNECGIGGAVLNLIIHEREFGPEFIDEEGEYVKV---VRSEGVANITFTVRGNPRP 4976

Query: 205  QKVAYTNGTDHSSTDDFKVDTF---EYRLLREVSFRESITKRYVGES------------- 248
            + + Y +GT  S T   ++DT    +   L   S        Y+ E+             
Sbjct: 4977 EVIWYKDGTLLSDTT--RMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCIL 5034

Query: 249  DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
            DVQ   + +   G +  P I +K R+++ +EG++ +F++ +  +P P V W++   +L +
Sbjct: 5035 DVQAVPKEEVDHGQIVKPVITRKIRDAQGEEGSNIRFEIHVKSHPPPHVEWYRGSIKLAH 5094

Query: 309  SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRS 368
              K++I       +L +   QK D                          T SY     +
Sbjct: 5095 GPKYQISEGDGAYSLTITGVQKDD--------------------------TGSYKVVATN 5128

Query: 369  QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWF 426
            Q  + T + E    + + +K LAP+  ++     +T   G     +  + G+P P V W+
Sbjct: 5129 QAGSSTSRAE----VVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIRGKPKPSVVWY 5184

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVVTCVARNKSGETAFQCRLNVIEK 485
             +  +I    N  + +   G+   +I   T S+ +G  +C A +K G T+ +  + +   
Sbjct: 5185 KDGNKILTSRN--VQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAKFDVQIQAP 5242

Query: 486  EQVV-APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            E    AP F+++    N REG+ V  + +  G P P I W +DGV +  +  +    DG 
Sbjct: 5243 EAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGYPEPEIEWTRDGVSMESDERVTTWYDGE 5302

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             STL I  A  +D+  Y+CT +N +G  ++ A L
Sbjct: 5303 HSTLSIHNANHADSGMYKCTLKNNSGWASSSAEL 5336



 Score =  115 bits (277), Expect = 8e-25
 Identities = 86/302 (28%), Positives = 135/302 (44%), Gaps = 35/302 (11%)

Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN-HTTLRVRNTQKSDSGHYT 337
           E  +A+F V + G P+P V W++   ++ +S KH+I+   +   +L +++  K D+G Y 
Sbjct: 4   ESGEARFDVTIEGYPKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYK 63

Query: 338 LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
                   C+ T+                      D  Q      + + EK +APQ  + 
Sbjct: 64  --------CVATN----------------------DAGQTSLRGDLSVKEKQIAPQIKEK 93

Query: 398 CQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
            Q+  +V EG+    D  +TG+P PEV W+ + + +R   +   L +   ++ L I   T
Sbjct: 94  EQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSID-LKSTDDSYFLSIPKAT 152

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
            +DSG   C A+NK G +A    +NV  K +  AP          V+EGE         G
Sbjct: 153 PNDSGKYKCEAKNKIGTSARDFDVNVKVKGK--APTVTSELKPDKVQEGEQYKFTCAVTG 210

Query: 517 TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
            P P I+W KDG PI  +  ++   DG  STL I   K  D   Y+    N  GS ++ A
Sbjct: 211 KPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTA 270

Query: 577 RL 578
            L
Sbjct: 271 DL 272



 Score =  113 bits (273), Expect = 2e-24
 Identities = 100/388 (25%), Positives = 161/388 (41%), Gaps = 24/388 (6%)

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
            T    +  T    V    + S  P   +K +     +   A+F V  +G P P + W+ E
Sbjct: 3760 TATNQEGSTSSSAVIVVNRASITPRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWFHE 3819

Query: 4448 NFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG--TAKCSANLVVEEKRR 4505
            +  I +   ++I        L+IR V       +  +A N  G  TA C  ++  ++   
Sbjct: 3820 STKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQDFAP 3879

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
               G  +P       + + V  G  V +   V G     V W K+G+ +  +  N  L  
Sbjct: 3880 IVAGSEMP-------EPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLS-NTNNLHLRA 3931

Query: 4566 DGTY-TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPE 4624
             G Y  L +L+    DSG Y+ VA N  G A      + +L  T   PK +  +    P 
Sbjct: 3932 RGEYFNLDLLKTTQADSGTYKFVATNDLGSAYR----IFNLNVTAIAPKEKWSS----PI 3983

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
             +  L    V EG   +F   + G PLP++QWYK D  I  +   +         L I +
Sbjct: 3984 FVTELSPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQ 4043

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQ 4743
               ED+G YK V  N +G  T +AKL V    +    PA+T L RD+  ++G  ++   Q
Sbjct: 4044 ITLEDQGQYKVVLKNESGSATSSAKLSVR---EEYGKPAITQLYRDVEGFDGSESELTVQ 4100

Query: 4744 ITSKIKPTIQWLR-EGALIPETPDFQMI 4770
            ++      ++W R +  L P    +++I
Sbjct: 4101 VSGVPAAEVEWFRGKTKLFPSERSYKII 4128



 Score =  113 bits (272), Expect = 3e-24
 Identities = 113/522 (21%), Positives = 212/522 (40%), Gaps = 45/522 (8%)

Query: 65   RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
            +P E +P +  Q+ ++AR  +  + +    ++G P P   W +   P+      S  ++ 
Sbjct: 1602 KPKEEAPKLTSQL-RSARITESDDFELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDG 1660

Query: 125  QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184
            +    +L  K++   D+G YT T +N +G    S  +                    +  
Sbjct: 1661 KK--CTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSKPEILETMKDAEGIET 1718

Query: 185  TVEHKAYGTQGYTTEQSRQTQKVAYT-NGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
                     + Y   +     + A   +G  +  T D +  T+   +  ++   +  T +
Sbjct: 1719 GKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTI-NDLRLEDCGTYK 1777

Query: 244  YVGESDVQISTEI------DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
             V  +D+  ++E       ++ + P    +  + P  +K  E +D +    ++G P P V
Sbjct: 1778 IVAFNDIGKTSERAELTVKEKLIAPEFEGRETEVPFRAK--EKSDLEVSYNINGKPSPDV 1835

Query: 298  TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            +W+++ + L++  K        H   +  NT +     +T+         V++G      
Sbjct: 1836 SWYRDDRLLLDGRK--------HELRKRGNTYR-----FTVFN-------VSAG------ 1869

Query: 358  PTESYVQDQRSQYITDTQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVT 416
               SY  + +++  + T+    E  IE+ + +  AP F    +  DVTEG+   F CRV 
Sbjct: 1870 DAGSYRCEAKNRVGSATRNFNVE--IEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVH 1927

Query: 417  GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
             RP P VTW+ N  +I  D   +    +   + L++ ++ + D+G   C+A N  G+   
Sbjct: 1928 ARPEPSVTWYRNKNEIVPDGRSRTTF-DGETYKLILQDIKIKDAGQYECIASNPIGKAFC 1986

Query: 477  QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE 536
               + V ++E  V P   E   T  V EG    +  +  G P P + W      ++    
Sbjct: 1987 TAEMTVNKRE--VKPVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDR 2044

Query: 537  LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             ++  +G   TL I       AA Y+C A N AG T  RA L
Sbjct: 2045 FQVTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADL 2086



 Score =  113 bits (272), Expect = 3e-24
 Identities = 81/303 (26%), Positives = 138/303 (45%), Gaps = 26/303 (8%)

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
            N   + G        L GNPRP V W+++G  L ++ + +I +  +   + +      D+
Sbjct: 3391 NKVAKAGGFVNISFTLKGNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDA 3450

Query: 334  GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393
            G+Y   A +  G  + S  L ++ P+    ++++                 IS KAL  Q
Sbjct: 3451 GNYVCEARSRIGTAIRSCTLEIKVPSMGGPEEKK-----------------IS-KALIGQ 3492

Query: 394  FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL-VNESGNHALMI 452
                  D    EG   +F  R+TG PYP V W+    ++ D   +KI    E G ++L++
Sbjct: 3493 GDN---DVQAVEGWKVQFQTRITGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIV 3549

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV--ERFSTLNVREGEPVVL 510
             +VT  D G   C+A N +G +A  CR+N+  K++  AP+    E    LNV EG+ + +
Sbjct: 3550 NDVTKDDIGTYKCLATNSAGSSA--CRINLDVKDKQYAPEIPGHEDRQELNVPEGQEINM 3607

Query: 511  NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            +      P   ++W KDG  +     + I + G    L IP A   D+  Y+C   +  G
Sbjct: 3608 DVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLYKCEGVSTLG 3667

Query: 571  STA 573
            +++
Sbjct: 3668 TSS 3670



 Score =  113 bits (271), Expect = 4e-24
 Identities = 127/516 (24%), Positives = 210/516 (40%), Gaps = 50/516 (9%)

Query: 61   ITAGRPGEP-SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYS 119
            +TA  P E  S PIF          +G   KF   + G P P + W +   P+   ++  
Sbjct: 3970 VTAIAPKEKWSSPIFVTELSPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRIR 4029

Query: 120  MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXY 179
              ++     V LLI QI   D+G+Y    +N+ G A  S  +                 Y
Sbjct: 4030 TFFDGHV--VKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVR---EEYGKPAITQLY 4084

Query: 180  RHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRES 239
            R V           +G+   +S  T +V+   G   +  + F+  T  +    E S++  
Sbjct: 4085 RDV-----------EGFDGSESELTVQVS---GVPAAEVEWFRGKTKLFP--SERSYKII 4128

Query: 240  ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL-QEGADAQFQVQLSGNPRPRVT 298
             T  Y G +   I   +   L    P  I +  + SK+ +E   A     + GNPRP V 
Sbjct: 4129 ATNEY-GRTGALIDLTVKERL--FGPEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVF 4185

Query: 299  WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            WFK+G +L  +++ ++ +  +   L +      D+G Y   A +  G    S  L V++ 
Sbjct: 4186 WFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKA- 4244

Query: 359  TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGR 418
                V+ +R   +                +A  PQ  K+     V EG   + D R+TG 
Sbjct: 4245 ----VRPRRGNEV----------------QACKPQTSKMANVTAV-EGWKVQLDTRMTGY 4283

Query: 419  PYPEVTWFINDRQIRDDYNHKIL-VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P P V WF  + +I D   +K   + + G ++L+I++V L DSG    VA N  GE    
Sbjct: 4284 PVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTL 4343

Query: 478  CRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
              L V  K      +     S L  R+G+ V + A     P  ++ W KDG+ +  +  +
Sbjct: 4344 AELTVKGKHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHP-KQVIWYKDGIRLEDSRRV 4402

Query: 538  RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
             + + G    + +P A   D+  Y+C   +   +T+
Sbjct: 4403 NLRSVGERYYVVVPSASFEDSGIYKCETTSEKETTS 4438



 Score =  112 bits (270), Expect = 6e-24
 Identities = 96/426 (22%), Positives = 176/426 (41%), Gaps = 23/426 (5%)

Query: 4395 QTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNS 4454
            +   + + G  + +  P   +K     + E   +RF+V   G P P ++W+  +  + + 
Sbjct: 2513 EASSKALVGVNRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLTDG 2572

Query: 4455 PDFQIHTFSTKSI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
              ++I +     +  L++ +V ++ +  +  VA N  G A+   +L V E+       + 
Sbjct: 2573 VKYRIESNPEIGLYSLVVSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER-------LY 2625

Query: 4513 PPSFTLTAQNVN--VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
             P F       +  V  G  V +   + G     V W K+G  +    R  +        
Sbjct: 2626 APEFLEDDGEWSKVVRKGGFVNITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQY 2685

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
              I    P+D+G Y C A N  G +     C + +   K      T+   AP ++I P+K
Sbjct: 2686 CNIFFVGPEDTGTYVCEAHNRLGSS--FRSCTIEIKEPKSVDSTDTR---APGQLI-PVK 2739

Query: 4631 DKIVAEG-QAIEFSCKIVGK--PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR--ISEA 4685
             K   EG    +  C ++ K   +  ++W++G  +++    +++ ++ D  TL   +   
Sbjct: 2740 HKFDFEGVPGGKARCDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENV 2799

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD-NLPALTPLRDIVVYEGQPAQFKTQI 4744
              ED G Y+CV +  AG+ T+  +L + +  QA   L          + +GQ       +
Sbjct: 2800 CGEDAGTYRCVVHTPAGQTTIRGELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTV 2859

Query: 4745 TSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET 4804
            T    P I W ++G  + +T    +   GN   L I N   ED GT+TC A    G    
Sbjct: 2860 TGSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYR 2919

Query: 4805 SAKLVV 4810
            S ++ V
Sbjct: 2920 SFEVDV 2925



 Score =  109 bits (261), Expect = 7e-23
 Identities = 111/515 (21%), Positives = 203/515 (39%), Gaps = 45/515 (8%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F    +     +G + +    + G P P V W R +  +    ++   Y+   G+VS 
Sbjct: 1021 PTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYD---GNVSA 1077

Query: 132  L-IKQIGPGDEGEYTCTARNQYGEA-------ICSVYIQPEGXXXXXXXXXXXXXYRHVS 183
            L +K+    D+G Y C   N +G         +   +++PE                + +
Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPEVLQKMDDVRTVEGGKANFA 1137

Query: 184  ETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKR 243
              ++        +    ++ T    +   TD  +   + +   + +L    + + S T  
Sbjct: 1138 VKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCS-YILFIDDVKLDDAGTVKCSATNA 1196

Query: 244  YVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
              G++ V+   E++     V+P    ++ R  +++EG +A    ++SG P+P VTW+   
Sbjct: 1197 -AGKTVVRADLEVEEK--NVAPSFHGRQGR-LRVKEGREASVYFEISGKPKPSVTWY--- 1249

Query: 304  QRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYV 363
                   K +++       + + +  +  S ++T+    P                 +Y 
Sbjct: 1250 -------KDDVVIGDEDRNVDIYS--RGSSYYFTIKQARPED-------------KGTYK 1287

Query: 364  QDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEV 423
             + R+   T  +    +  ++  E  +AP+  +  Q  DVTEG   R  C+V+G P P +
Sbjct: 1288 CEARNDVGTAFETFPIDVEVK-QEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTL 1346

Query: 424  TWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
             W  N+  + D+   K    +     L I NVTL+D+     V RN +GE +   +L VI
Sbjct: 1347 EWLKNNELLSDNDRFKTRF-DGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVI 1405

Query: 484  EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
             K     P+ +E+   +   EG+    N +  G P+P I W      I      +   D 
Sbjct: 1406 RK--CTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDD 1463

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               +L I      D   Y+C A N AG    RA L
Sbjct: 1464 QKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAEL 1498



 Score =  109 bits (261), Expect = 7e-23
 Identities = 96/384 (25%), Positives = 166/384 (43%), Gaps = 26/384 (6%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P + W+++   +  +    + +  +   L I  +  +D+  +   A +R GT   S
Sbjct: 4178 GNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRS 4237

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS--GQLVRLDTKVTGTKPIDVYWLKNGKK 4553
              L V+  R + RG  V      T++  NVT+  G  V+LDT++TG     V W +  +K
Sbjct: 4238 CTLDVKAVRPR-RGNEVQACKPQTSKMANVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEK 4296

Query: 4554 VQPDIRNKI--LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            +    R K   +E++G Y+L+I +   +DSG Y  VA N+ GEA   AE  V        
Sbjct: 4297 ITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTV-------- 4348

Query: 4612 PKPQTKAANAPPEIIE-PLKDKIV-AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYF 4669
                 K  +   E+ E     ++   +GQ +     +   P   + WYK    ++ S+  
Sbjct: 4349 -----KGKHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHPKQVI-WYKDGIRLEDSRRV 4402

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLR 4728
             +    + Y + +  A  ED G YKC   +     +    + +    ++   P   + LR
Sbjct: 4403 NLRSVGERYYVVVPSASFEDSGIYKCETTSEKETTSQLFDIHIEDVCKSALAPGFKSALR 4462

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEE 4786
             + V E + A+F+ +++    P IQW       P + D ++I   +  V  L I     +
Sbjct: 4463 SLDVTEDESAEFRCEVSGSPAPRIQWFMNDQ--PVSRDSRIITSSDGPVHKLAITKATLQ 4520

Query: 4787 DTGTFTCRATTAAGQVETSAKLVV 4810
            DTG + C A    G   ++A L V
Sbjct: 4521 DTGVYKCLAVNDNGSATSTADLNV 4544



 Score =  107 bits (258), Expect = 2e-22
 Identities = 113/517 (21%), Positives = 204/517 (39%), Gaps = 44/517 (8%)

Query: 70   SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
            S P F          +G +   E ++ G P P V W +   P+   +     ++ +   +
Sbjct: 4751 SAPSFVIELTPTTVTEGESTALEVEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKV--I 4808

Query: 130  SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET---V 186
             L++++    D G Y CT  N  G A     +                    V  T   +
Sbjct: 4809 RLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAVEGTEVRL 4868

Query: 187  EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG 246
            E   +G      E  R    V  TN   ++ ++     T    ++R  +  ++   + +G
Sbjct: 4869 EVIKFGCPMPKVEWFR--DNVQLTNNDRYTISETEDTSTL---VIRNCTTNDTGPYKVIG 4923

Query: 247  ESDVQISTEI------DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF 300
             ++  I   +      +R  GP    +  +  +  + +  A+  F V+  GNPRP V W+
Sbjct: 4924 TNECGIGGAVLNLIIHEREFGPEFIDEEGEYVKVVRSEGVANITFTVR--GNPRPEVIWY 4981

Query: 301  KNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
            K+G  L ++ + +  +  +   L + +    D+G Y   A +  G    S  L V     
Sbjct: 4982 KDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCILDV----- 5036

Query: 361  SYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPY 420
                           Q   +E ++  +  + P   +  +D    EG   RF+  V   P 
Sbjct: 5037 ---------------QAVPKEEVDHGQ-IVKPVITRKIRDAQGEEGSNIRFEIHVKSHPP 5080

Query: 421  PEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            P V W+    ++     ++I   + G ++L IT V   D+G    VA N++G +    R 
Sbjct: 5081 PHVEWYRGSIKLAHGPKYQISEGD-GAYSLTITGVQKDDTGSYKVVATNQAGSST--SRA 5137

Query: 481  NVIEKEQVVAPKFVERFST--LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR 538
             V+ K++ +APK  E  +T  + +  G  + LN    G P P + W KDG  I+ +  ++
Sbjct: 5138 EVVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIRGKPKPSVVWYKDGNKILTSRNVQ 5197

Query: 539  IHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
            I + G    L I   K+  A  Y C A +  G+T+ +
Sbjct: 5198 IRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAK 5234



 Score =  107 bits (256), Expect = 3e-22
 Identities = 138/683 (20%), Positives = 266/683 (38%), Gaps = 62/683 (9%)

Query: 68   EPSPPIFEQIFKNARFA--QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
            + +P   ++     +F+  QG        + G+PTP ++W +   PL +  +  +R    
Sbjct: 2830 QQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRIDIR---S 2886

Query: 126  TGDVSLL-IKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE 184
             G+V  L I  + P D G YTC A N+ G A  S  +                  R ++ 
Sbjct: 2887 RGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPKVKGEAPSFSLELRPIAA 2946

Query: 185  TVEHKAYGTQGYTTEQSRQTQKVAYT-NGTDHSSTDDFKVD---TFEYRLLREVSFRESI 240
              E   + ++       +   ++ +T NG    S    + D      Y  + +VS  ++ 
Sbjct: 2947 IEE---FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAG 3003

Query: 241  TKRYVGESDV-QISTEIDRSLGPVSP-PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT 298
            T   +  +    +S+    ++   +  P I  K  + K  EG +A+F ++++G+P P V 
Sbjct: 3004 TYECIASNAAGTVSSSAALTVSRRNMRPLITHKLHDMKAYEGKEARFDIEVTGHPSPTVE 3063

Query: 299  WFKNGQRLINSNKHEIITTHNH--TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
            WFK    +    ++++++       +L V +    D G Y  +A+N          LA +
Sbjct: 3064 WFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDGIYKCVAQN----------LAGK 3113

Query: 357  SPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT 416
            + T + +      +  +  + E+ + + ++E                  G+  +    V 
Sbjct: 3114 ASTRAMLDVIARDFGPEFDEEESPKPVIVNE------------------GEEAQMMVSVR 3155

Query: 417  GRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETA 475
            GRP   V WF + + + D  + ++ V   GN H L+I +VT  D G   CVA + +G ++
Sbjct: 3156 GRPKAVVEWFKDGKFLYD--SRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSS 3213

Query: 476  --FQCRLNVIE-KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
              F   + V + K++   P F  +   L   EGE         G P P + W KD  PI 
Sbjct: 3214 RTFDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIK 3273

Query: 533  PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKR 592
                 R + DG    L   +  + + +  +  A +VAG        +          + R
Sbjct: 3274 HEDRFRTYFDGRVCMLVFRKTDSFECSEARLEA-HVAGVPRPTVEWFLGSAKLCDGERYR 3332

Query: 593  LHLPRPTKVXXXXXXXXXXXXYLRHVE-----RARPYIPPGEEDRVYPPPQFIVP--LKS 645
            L                      + +           +    ++R++  P+F+    + +
Sbjct: 3333 LEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKERLF-GPEFLEEEGVWN 3391

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
              A  GG ++    ++  G+P   + W ++G  +  ++R     R     +++  L ++D
Sbjct: 3392 KVAKAGGFVNISFTLK--GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLED 3449

Query: 706  SGEYTCRAVSATGVAETKAVLHV 728
            +G Y C A S  G A     L +
Sbjct: 3450 AGNYVCEARSRIGTAIRSCTLEI 3472



 Score =  106 bits (255), Expect = 4e-22
 Identities = 118/522 (22%), Positives = 210/522 (40%), Gaps = 61/522 (11%)

Query: 77   IFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQ 135
            +F+     +   A+ E  + G P P V W    A L +  +Y +   EQT ++ +L+I  
Sbjct: 3290 VFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRL---EQTDNLYTLVISN 3346

Query: 136  IGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQG 195
            +   D G Y   A N++G     V +  +              +  V++      +    
Sbjct: 3347 LHMEDTGPYKIIATNEHGSTGSVVDLTVKERLFGPEFLEEEGVWNKVAKA---GGFVNIS 3403

Query: 196  YTTEQSRQTQKVAYTNGT---DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQI 252
            +T + + +   V Y +G    D +  D        Y  +  ++  ++    YV E+  +I
Sbjct: 3404 FTLKGNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDA--GNYVCEARSRI 3461

Query: 253  STEIDRSL---------GP----VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
             T I             GP    +S   I Q   + +  EG   QFQ +++G P P V W
Sbjct: 3462 GTAIRSCTLEIKVPSMGGPEEKKISKALIGQGDNDVQAVEGWKVQFQTRITGYPYPHVEW 3521

Query: 300  FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
            ++   +L +S+K++I              Q  + G Y+L+               V   T
Sbjct: 3522 YRGTIKLHDSDKYKI-------------AQTKEDGLYSLI---------------VNDVT 3553

Query: 360  ESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV--KVCQDRDVTEGKMTRFDCRVTG 417
            +  +   +               +++ +K  AP+    +  Q+ +V EG+    D  +  
Sbjct: 3554 KDDIGTYKCLATNSAGSSACRINLDVKDKQYAPEIPGHEDRQELNVPEGQEINMDVVIKS 3613

Query: 418  RPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGETA- 475
            +P  EV+W+ +   ++D    +I +   G+H  L+I +    DSG+  C   +  G ++ 
Sbjct: 3614 KPRLEVSWYKDGELLQD--TKRIDIRSRGDHYYLVIPSAAPEDSGLYKCEGVSTLGTSSK 3671

Query: 476  -FQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534
             F  +  V +  +V  PKF+   ++L+V EG+   L  +  G P P + W KD   I  N
Sbjct: 3672 TFDVKAGVPDGSRVT-PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQLITNN 3730

Query: 535  PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
              +R    G   TL        D   Y+CTA N  GST++ A
Sbjct: 3731 DRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSA 3772



 Score =  105 bits (251), Expect = 1e-21
 Identities = 82/372 (22%), Positives = 151/372 (40%), Gaps = 22/372 (5%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            WY++   +++S    + +   +  +++     EDS ++     +   T     ++ +E+ 
Sbjct: 4389 WYKDGIRLEDSRRVNLRSVGERYYVVVPSASFEDSGIYKCETTSEKETTSQLFDIHIEDV 4448

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL 4563
             +      + P F    ++++VT  +      +V+G+    + W  N + V  D R    
Sbjct: 4449 CKSA----LAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFMNDQPVSRDSRIITS 4504

Query: 4564 EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP 4623
             +   + L I +A  QD+G Y+C+A+N  G A   A+  VS    K             P
Sbjct: 4505 SDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMK-------------P 4551

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG-DKLIKPSKYFQMSRTADEYTLRI 4682
              +E L++     G    FS ++ G P P + WYK   +LI   + F +S   D Y L I
Sbjct: 4552 TFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGR-FHISEEGDLYNLTI 4610

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK- 4741
                 +D G Y C+  N+ G+ T  ++L V   + A   P       + V   Q ++ + 
Sbjct: 4611 ENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEEFAPFFPEDEGQGAVPVVTRQDSEVEL 4670

Query: 4742 -TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL-IGNTYEEDTGTFTCRATTAA 4799
               +    KP + W ++   +    D   +   +N   L       +D G + C AT   
Sbjct: 4671 GAVVRGSPKPEVAWYKDDEDVATDADGLDVGSRDNVYFLRFARPSVKDGGLYKCVATNEH 4730

Query: 4800 GQVETSAKLVVK 4811
            G+      L V+
Sbjct: 4731 GEASMLFNLDVE 4742



 Score =  103 bits (247), Expect = 4e-21
 Identities = 115/510 (22%), Positives = 200/510 (39%), Gaps = 53/510 (10%)

Query: 86   GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEY 144
            GG       L+GNP P V W R    L +  +  +R     GD+  + I  +   D G Y
Sbjct: 3397 GGFVNISFTLKGNPRPHVVWYRDGILLYDTTRMDIR---SRGDLHYVNIYGLTLEDAGNY 3453

Query: 145  TCTARNQYGEAI--CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEH-KAYGTQGYTTEQS 201
             C AR++ G AI  C++ I+                       V+  + +  Q  T    
Sbjct: 3454 VCEARSRIGTAIRSCTLEIKVPSMGGPEEKKISKALIGQGDNDVQAVEGWKVQFQTRITG 3513

Query: 202  RQTQKVAYTNGTDH-SSTDDFKV-DTFE---YRLL------REVSFRESITKRYVGESDV 250
                 V +  GT     +D +K+  T E   Y L+       ++   + +     G S  
Sbjct: 3514 YPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSAC 3573

Query: 251  QISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
            +I+ ++ D+   P  P    ++  N  + EG +    V +   PR  V+W+K+G+ L ++
Sbjct: 3574 RINLDVKDKQYAPEIPGHEDRQELN--VPEGQEINMDVVIKSKPRLEVSWYKDGELLQDT 3631

Query: 310  NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
             + +I               +S   HY L+   P+     SG    E           S 
Sbjct: 3632 KRIDI---------------RSRGDHYYLVI--PSAAPEDSGLYKCEGV---------ST 3665

Query: 370  YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIND 429
              T ++  + +  +    + + P+F+      DV EG   +  C++ G+P P V WF +D
Sbjct: 3666 LGTSSKTFDVKAGVPDGSR-VTPKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDD 3724

Query: 430  RQIRDDYNHKILVNESGNHALMI-TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV 488
            + I +  N ++  +  GN   +I   V + D G   C A N+ G T+    + V+ +  +
Sbjct: 3725 QLITN--NDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVI-VVNRASI 3781

Query: 489  VAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
              P+ +E+   ++  +G       R  G P P++TW  +   I+      I   G   +L
Sbjct: 3782 T-PRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWFHESTKIVSRGRYEISRVGDLYSL 3840

Query: 549  DIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             I   +      Y+C A N AG       L
Sbjct: 3841 VIRGVEYLHVGTYKCIATNDAGKVTAHCHL 3870



 Score =  103 bits (246), Expect = 5e-21
 Identities = 96/326 (29%), Positives = 145/326 (44%), Gaps = 41/326 (12%)

Query: 249  DVQISTEIDRSLGPVSPPKIAQK-PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI 307
            DVQI         P +P  + Q  P+N++  EG   +F  +++G P P + W ++G  + 
Sbjct: 5236 DVQIQAP---EAAPKAPAFLKQLLPQNAR--EGDVVKFSCKVTGYPEPEIEWTRDGVSME 5290

Query: 308  NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
            +  +        H+TL + N   +DSG Y    +N +G   +S  L V   T+       
Sbjct: 5291 SDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKTQRPRLSDN 5350

Query: 368  SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
             + +  T   E   R E++ KA  P+  K+C  +D                   E+T   
Sbjct: 5351 MKELFATVGGEA--RFEVTMKA-TPK-PKICWYKD-------------------EIT--- 5384

Query: 428  NDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
               + RD Y  K    E G + L+I  V LSDSG    VA NK+G+T F   L V+EK  
Sbjct: 5385 --LRSRDRYTMK---EEDGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK-- 5437

Query: 488  VVAPKFVERFSTLNV--REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545
             VAP+F +R +   V   EG  V L+    G P P + W K+G  +  +  L + T G  
Sbjct: 5438 TVAPEFPDRETLEQVVGVEGREVELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDT 5497

Query: 546  STLDIPRAKASDAAWYQCTAQNVAGS 571
              + IP AK   +  Y+C A N  G+
Sbjct: 5498 HYVWIPSAKHEHSGRYRCEATNSNGT 5523



 Score =  102 bits (244), Expect = 8e-21
 Identities = 80/303 (26%), Positives = 124/303 (40%), Gaps = 34/303 (11%)

Query: 279  EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
            +G D      + G P+P + W K+G+ L N+   +I    +   L +      D+G YT 
Sbjct: 935  DGQDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTC 994

Query: 339  LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
             A+N  G +                    S+ +T T +        + +K   P F+   
Sbjct: 995  RAKNNAGIV--------------------SKDVTITVEA-------LQKKGDTPTFMSKL 1027

Query: 399  QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTL 457
            +  ++TEG   +  C VTGRP PEV WF ++  I+     K   +  GN  AL +    L
Sbjct: 1028 EPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFK--ASYDGNVSALTVKEAEL 1085

Query: 458  SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
             D GV  CV  N  G  + +  + V++K   + P+ +++   +   EG       +    
Sbjct: 1086 DDDGVYKCVVTNNFGSVSSKADVTVLKKH--LRPEVLQKMDDVRTVEGGKANFAVKIDAF 1143

Query: 518  PTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
            P P I W      I      +I TD    +  L I   K  DA   +C+A N AG T  R
Sbjct: 1144 PKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVR 1203

Query: 576  ARL 578
            A L
Sbjct: 1204 ADL 1206



 Score = 98.3 bits (234), Expect = 1e-19
 Identities = 52/199 (26%), Positives = 95/199 (47%), Gaps = 2/199 (1%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            T   ++++EK  AP+F       D  +G+       V G+P PE+ W  +  ++R+  + 
Sbjct: 909  TRAELKVNEKHFAPEFEDWKDTIDALDGQDVNISTWVRGKPKPEIVWLKDGEELRNTMHV 968

Query: 439  KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERF 497
            +I       H L++  V+  D+G+ TC A+N +G  +    + V   +++   P F+ + 
Sbjct: 969  QIKCY-GDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEALQKKGDTPTFMSKL 1027

Query: 498  STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
              + + EG+   L+    G P P + W +D V I P+   +   DG  S L +  A+  D
Sbjct: 1028 EPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDD 1087

Query: 558  AAWYQCTAQNVAGSTATRA 576
               Y+C   N  GS +++A
Sbjct: 1088 DGVYKCVVTNNFGSVSSKA 1106



 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 68/274 (24%), Positives = 124/274 (45%), Gaps = 11/274 (4%)

Query: 4537 VTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            V G     V+W K+G ++    R  +   D    L I    P D+G Y C A +  G   
Sbjct: 4176 VLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGT-- 4233

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
            C   C + + A + +   + +A    P+  + + +    EG  ++   ++ G P+P V+W
Sbjct: 4234 CFRSCTLDVKAVRPRRGNEVQACK--PQTSK-MANVTAVEGWKVQLDTRMTGYPVPIVEW 4290

Query: 4657 YKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            ++G++ I     ++ +R  DE  Y+L IS+   ED G Y+ VA N+ G  T  A+L V  
Sbjct: 4291 FRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTVKG 4350

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
               A  L        +   +GQ    K  + +  K  I W ++G  + ++    +   G 
Sbjct: 4351 KHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHPKQVI-WYKDGIRLEDSRRVNLRSVGE 4409

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
               +++ +   ED+G + C  T+   + ET+++L
Sbjct: 4410 RYYVVVPSASFEDSGIYKCETTS---EKETTSQL 4440



 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 107/506 (21%), Positives = 184/506 (36%), Gaps = 39/506 (7%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-S 130
            P F+   ++    +  +A+F  ++ G+P P + W     P+   ++ S       G V  
Sbjct: 4455 PGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFMNDQPV---SRDSRIITSSDGPVHK 4511

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L I +    D G Y C A N  G A  +  +                    V       +
Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGEASFS 4571

Query: 191  YGTQGYTTEQSRQTQKVA--YTNGTDHSSTD-DFKVDTFEYRLLREVSFRESITKRYVGE 247
               +G+   +    + +      G  H S + D    T E     +      I    VG+
Sbjct: 4572 VRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGK 4631

Query: 248  SDVQISTEID-RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
               +    ++     P  P    Q       ++ ++ +    + G+P+P V W+K+ + +
Sbjct: 4632 ETCRSQLVVEAEEFAPFFPEDEGQGAVPVVTRQDSEVELGAVVRGSPKPEVAWYKDDEDV 4691

Query: 307  I-NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
              +++  ++ +  N   LR       D G Y  +A N +G       +      E +V +
Sbjct: 4692 ATDADGLDVGSRDNVYFLRFARPSVKDGGLYKCVATNEHG----EASMLFNLDVEGHVPE 4747

Query: 366  QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
                                 E   AP FV       VTEG+ T  +  +TG P P+V W
Sbjct: 4748 ---------------------EDWSAPSFVIELTPTTVTEGESTALEVEITGTPLPKVEW 4786

Query: 426  FINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
            F ND+ ++ D  H +     G    L++   TL D+G+  C   N  G  +    L+V  
Sbjct: 4787 FKNDKPVKHD--HLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV-- 4842

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
               +  P+  E+ + ++  EG  V L     G P P++ W +D V +  N    I     
Sbjct: 4843 NRALTKPEVAEKMTDIDAVEGTEVRLEVIKFGCPMPKVEWFRDNVQLTNNDRYTISETED 4902

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAG 570
             STL I     +D   Y+    N  G
Sbjct: 4903 TSTLVIRNCTTNDTGPYKVIGTNECG 4928



 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 109/480 (22%), Positives = 179/480 (37%), Gaps = 39/480 (8%)

Query: 61   ITAGRP-GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYS 119
            + AG P G    P F     +    +G +AK   K+ G P P V W +    +   N   
Sbjct: 3675 VKAGVPDGSRVTPKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQLIT--NNDR 3732

Query: 120  MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXY 179
            +R +      +L+ + +   D G Y CTA NQ G    S  I                  
Sbjct: 3733 VRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNRASITPRIIEKPRDV 3792

Query: 180  RHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRES 239
              V  T        +G+   Q + T     T        +  +V      ++R V +   
Sbjct: 3793 DAVDGTDAKFTVRVEGFP--QPKVTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHV 3850

Query: 240  ITKRYVGESD---VQISTEIDRSLGPVSPPKI-AQKPRNSKLQEGADAQFQVQLSGNPRP 295
             T + +  +D   V     +D +    +P    ++ P    ++EG +      + G P P
Sbjct: 3851 GTYKCIATNDAGKVTAHCHLDVTKQDFAPIVAGSEMPEPIVVREGCEVSMMANVRGKPAP 3910

Query: 296  RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
             V WFK+GQ         +++  N+  LR R    +     T  A++      T  ++A 
Sbjct: 3911 TVEWFKDGQ---------LLSNTNNLHLRARGEYFNLDLLKTTQADSG-----TYKFVAT 3956

Query: 356  ESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRV 415
                 +Y    R   +  T        I   EK  +P FV       VTEG  T+F   V
Sbjct: 3957 NDLGSAY----RIFNLNVTA-------IAPKEKWSSPIFVTELSPLSVTEGDYTKFVAHV 4005

Query: 416  TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMITNVTLSDSGVVTCVARNKSGET 474
            +G P P + W+ +D  I    NH+I     G+   L+I  +TL D G    V +N+SG  
Sbjct: 4006 SGVPLPSIQWYKDDNPISS--NHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSA 4063

Query: 475  AFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534
                +L+V  +E+   P   + +  +   +G    L  +  G P   + W +    + P+
Sbjct: 4064 TSSAKLSV--REEYGKPAITQLYRDVEGFDGSESELTVQVSGVPAAEVEWFRGKTKLFPS 4121



 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 55/193 (28%), Positives = 94/193 (48%), Gaps = 5/193 (2%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + ++   + P+ ++      + EG  +RFD R+ G P PEV WF    ++ D   ++I  
Sbjct: 2520 VGVNRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLTDGVKYRIES 2579

Query: 443  N-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
            N E G ++L+++ V L  +G    VA N+ G+   Q  L++   E++ AP+F+E     +
Sbjct: 2580 NPEIGLYSLVVSKVQLDQTGHYRIVASNEHGKA--QALLDLTVNERLYAPEFLEDDGEWS 2637

Query: 502  --VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
              VR+G  V +    +G P P +TW KDG+ +       + + G     +I      D  
Sbjct: 2638 KVVRKGGFVNITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTG 2697

Query: 560  WYQCTAQNVAGST 572
             Y C A N  GS+
Sbjct: 2698 TYVCEAHNRLGSS 2710



 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 81/310 (26%), Positives = 133/310 (42%), Gaps = 39/310 (12%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            PK      +  + EG  A+   ++ G P P V WFK+ Q LI +N             RV
Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQ-LITNND------------RV 3733

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER--- 382
            R++   ++   TL+ E  N                  +QD+ +   T T Q  +      
Sbjct: 3734 RSSVVGNT--CTLIFETVN------------------IQDRGAYRCTATNQEGSTSSSAV 3773

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            I ++  ++ P+ ++  +D D  +G   +F  RV G P P+VTWF    +I     ++I  
Sbjct: 3774 IVVNRASITPRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWFHESTKIVSRGRYEI-- 3831

Query: 443  NESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
            +  G+ ++L+I  V     G   C+A N +G+    C L+V +++        E    + 
Sbjct: 3832 SRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQDFAPIVAGSEMPEPIV 3891

Query: 502  VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            VREG  V + A   G P P + W KDG  +     L +   G    LD+ +   +D+  Y
Sbjct: 3892 VREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTY 3951

Query: 562  QCTAQNVAGS 571
            +  A N  GS
Sbjct: 3952 KFVATNDLGS 3961



 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 106/470 (22%), Positives = 179/470 (38%), Gaps = 49/470 (10%)

Query: 4102 VEESKARCP-PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            +E  KAR   P F +    + V EGE   F CRV   P+P V W  N N IV   R + T
Sbjct: 1893 IEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWYRNKNEIVPDGRSRTT 1952

Query: 4161 YDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKNAPRPWYD 4219
            +DG  Y   +   +  D G+ E I             + V  R  + + V+K        
Sbjct: 1953 FDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR--EVKPVIK-------- 2002

Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279
                      E+ KTFE    +   G      E+K   +  P  EW     R  + + + 
Sbjct: 2003 ----------EVSKTFE----VSEGGTASI--EVKVSGVPVPTVEWYHGSNRVLDGDRFQ 2046

Query: 4280 KLQELENEQV-IKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRV- 4337
              QE +   + I++   + +     +  +     T    +     +   + E+  E+R+ 
Sbjct: 2047 VTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIA 2106

Query: 4338 ----QKKVTQKP--RIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEIT-RKITSTETTEI 4390
                Q  +T       P P      G  + ++ +K   K + G   +  RK T  +    
Sbjct: 2107 VREGQNAITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTY 2166

Query: 4391 EHKA-----QTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY 4445
              KA      T  R++       + P+F  K++P  V E +   +  +  G P P ++WY
Sbjct: 2167 ICKATNSIGSTSRRIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWY 2226

Query: 4446 RENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRR 4505
            R+N P++    +++        L + +   +D  V+  V  N  G+A  SA L V++K  
Sbjct: 2227 RDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKAN 2286

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            +       P       +V    G   R D + +G    +V W +N  KV+
Sbjct: 2287 K-------PKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVR 2329



 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 57/207 (27%), Positives = 91/207 (43%), Gaps = 6/207 (2%)

Query: 374 TQQRETEERIEISE-KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
           T  R  + +++++E +   P       D    +G+  +  C VTG P PEV WF + + +
Sbjct: 711 TAFRSFDIKVKVAEPQGETPTITTEMTDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPL 770

Query: 433 RDDYNHKILVN-ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
           +   NH+++ + E    AL    + L D G   CV  N  G  +    + V  +++ + P
Sbjct: 771 KA--NHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKV--EDRSLKP 826

Query: 492 KFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551
           + +      +  E E    +    G P P I W     PI+P     +  +G   +L I 
Sbjct: 827 EVITSMRDCDCVEEETASFHCEFSGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAIS 886

Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578
             K  DA  Y+C A N AG T TRA L
Sbjct: 887 DLKLEDAGNYKCVASNAAGKTTTRAEL 913



 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 64/224 (28%), Positives = 99/224 (44%), Gaps = 6/224 (2%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VF+S L  +   EGDN+ + C V     PT  +EW+ +N+PL + TR+K   D    SL 
Sbjct: 2193 VFVSKLRPLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLF 2250

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            ++    +D G+Y C  TNS GSA +S  L+     N     +       +E  E   + R
Sbjct: 2251 LSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVR 2310

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLH----LEGQVEPKNDPDLKIEWYFN 2950
             +   RP V                + +L E  V+     +  +V  +  P   I WY +
Sbjct: 2311 FSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKD 2370

Query: 2951 GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            G+++    RF++ S     T         D+G YTC+A NK G+
Sbjct: 2371 GEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGK 2414



 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 145/604 (24%), Positives = 234/604 (38%), Gaps = 76/604 (12%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV--SLD 2834
            +  + N+   EG +  FE  V+    P  K EWF ++K +   +R+K T D +    SL 
Sbjct: 284  VRKMENVESVEGSDAFFE--VKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLV 341

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            I+    +DSG Y C A+N  G       L+    KN  F  +   G   LE +E  E+  
Sbjct: 342  ISDLRLDDSGAYQCIASNEAGECNLRADLKV---KNKPFAPEFADGD--LEPIEVKEDQ- 395

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIE---WYFNG 2951
             A   R +V     P+  W       H   + + L   G V   + P         YF  
Sbjct: 396  -AVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLK-LKATGDVHELSIPKASTNDEGQYFCE 453

Query: 2952 KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011
                 GS  K T     V   +  V E  SG+   +   + G  ++ +T    + +  ++
Sbjct: 454  ASNPLGSP-KRTFKVTVVPKGVAPVIE--SGLMPLQVRKETGAKWSVNTTLDDAGEYKVK 510

Query: 3012 RTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEAS 3071
             T        L  I N++ +  K             PEF    +D+  +   Q+  +E  
Sbjct: 511  VTNEVGSVTSLADI-NVQKAKVK-------------PEFLRKVEDVTALETEQV-WFEIP 555

Query: 3072 LIPTGDQSMVIEWFYNGKTIEASHR--IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKW 3129
            +   G    ++EW+     I+   R  I       M  L I   +T DSG Y C A+N  
Sbjct: 556  I--QGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDA 613

Query: 3130 GQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189
            G+    + L+  +K    +P F   ++ IE +K G+ A     +     P  K+ WY + 
Sbjct: 614  GKTTALLNLDVNEKVV--QPEFDKEVKPIE-VKHGEEATTSLEIK--GKPKPKVTWYKDL 668

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYL 3249
             P+  +  I+  S      L+I      D G+Y C A NK G  F    I          
Sbjct: 669  VPLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIK--------- 719

Query: 3250 ESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPV 3309
                     K+ E       Q +TP+          T++ D+ + ++G+       +   
Sbjct: 720  --------VKVAE------PQGETPT--------ITTEMTDI-QAIDGEDCKLICHV--T 754

Query: 3310 DDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTK 3369
             +P+ +VEWF +GK L   HR     +  ++ L       E+ G Y+CV +N  G  S+ 
Sbjct: 755  GEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSA 814

Query: 3370 ANLK 3373
            A +K
Sbjct: 815  AEVK 818



 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 66/212 (31%), Positives = 96/212 (45%), Gaps = 7/212 (3%)

Query: 372  TDTQQRETEERIEISEKALAPQFV--KVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFIN 428
            T   Q      + I EK  AP F+  KV Q++  + +G+       VTG P P +TW+  
Sbjct: 2813 TPAGQTTIRGELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWY-K 2871

Query: 429  DRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE-KE 486
            D +  DD   +I +   GN + L I N+   D+G  TC A N+ G       ++V   K 
Sbjct: 2872 DGEPLDD-TRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPKV 2930

Query: 487  QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
            +  AP F      +   E     L     G P P+I W K+G P+  +  LR   DG  +
Sbjct: 2931 KGEAPSFSLELRPIAAIEEFDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIVA 2990

Query: 547  TLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             L I +    DA  Y+C A N AG+ ++ A L
Sbjct: 2991 YLSIWQVSHDDAGTYECIASNAAGTVSSSAAL 3022



 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 174/745 (23%), Positives = 289/745 (38%), Gaps = 158/745 (21%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK  VEW ++G  +  S R+          L + +V PED G+Y C A +  G +  +
Sbjct: 3156 GRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRT 3215

Query: 1798 STLFVQSKASLQLES--QHESALQKIQQLE-DSSRY------QRREDVEVAVNQAP---- 1844
              L V+        S     S L+ ++ LE + +++      +    VE   +  P    
Sbjct: 3216 FDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHE 3275

Query: 1845 -RFITQLNGPT-KLSEGQSAHYEC---RIEPYPD--PNMRVEWYFNGKVLQSGHRYRTSN 1897
             RF T  +G    L   ++  +EC   R+E +    P   VEW+     L  G RYR   
Sbjct: 3276 DRFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQ 3335

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQY 1957
                  L I  ++ ED+G Y                        II  ++H S    +  
Sbjct: 3336 TDNLYTLVISNLHMEDTGPY-----------------------KIIATNEHGSTGSVV-- 3370

Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNG 2017
               D   K  +    F+ E+  + K  K      G  V++  TL    +P   V WY +G
Sbjct: 3371 ---DLTVKERLFGPEFLEEEGVWNKVAK-----AGGFVNISFTLK--GNPRPHVVWYRDG 3420

Query: 2018 RPVQQGHRF--KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGL 2075
              +    R   ++  D  YV  +I     ED G Y+C+A + +G A+ + ++++      
Sbjct: 3421 ILLYDTTRMDIRSRGDLHYV--NIYGLTLEDAGNYVCEARSRIGTAIRSCTLEI------ 3472

Query: 2076 YLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEP 2135
                       K+  +   E  K I +   GQ    + A+       EG +  F+ R+  
Sbjct: 3473 -----------KVPSMGGPEEKK-ISKALIGQGDNDVQAV-------EGWKVQFQTRITG 3513

Query: 2136 INDPHLTIDWFHNGQKIRAGHRYRT--THDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
               PH  ++W+    K+    +Y+   T + G  +L +     +D GTY C ATN  G +
Sbjct: 3514 YPYPH--VEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSS 3571

Query: 2194 VNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTH 2253
               C + +      + D Q+          E  GH  R E+  P                
Sbjct: 3572 A--CRINLD-----VKDKQYAP--------EIPGHEDRQELNVP---------------- 3600

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
              EG+  + +  ++    P L + +Y +G+ LQ   R  I     +  L I    PED+G
Sbjct: 3601 --EGQEINMDVVIKS--KPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSG 3656

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTR 2373
             Y  + ++ LG  TS  S T   K  +      P+G                      +R
Sbjct: 3657 LYKCEGVSTLG--TS--SKTFDVKAGV------PDG----------------------SR 3684

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
              P F   L ++D + EG +A   C++    +PT  VEWF++++LI ++ R+  +     
Sbjct: 3685 VTPKFLSHLNSLD-VDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNT 3741

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
             ++    V  +D G Y C A+N  G
Sbjct: 3742 CTLIFETVNIQDRGAYRCTATNQEG 3766



 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 71/293 (24%), Positives = 122/293 (41%), Gaps = 24/293 (8%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            RL+  V G     V W     K+    R ++ + D  YTL+I   + +D+G Y+ +A N 
Sbjct: 3303 RLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNE 3362

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP--LKDKIVAEGQAIEFSCKIVGK 4649
             G      +  V             K     PE +E   + +K+   G  +  S  + G 
Sbjct: 3363 HGSTGSVVDLTV-------------KERLFGPEFLEEEGVWNKVAKAGGFVNISFTLKGN 3409

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P P V WY+   L+  +    +    D + + I     ED G+Y C A +  G    +  
Sbjct: 3410 PRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRSCT 3469

Query: 4710 LKVTQP-----DQADNLPALTPL--RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
            L++  P     ++     AL      D+   EG   QF+T+IT    P ++W R    + 
Sbjct: 3470 LEIKVPSMGGPEEKKISKALIGQGDNDVQAVEGWKVQFQTRITGYPYPHVEWYRGTIKLH 3529

Query: 4763 ETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            ++  +++     + +  L++ +  ++D GT+ C AT +AG       L VK K
Sbjct: 3530 DSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDVKDK 3582



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 110/515 (21%), Positives = 187/515 (36%), Gaps = 44/515 (8%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P   Q  +     +G + +   K+ G P P + W +    L + +++  R++ QTG  +L
Sbjct: 1315 PEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEWLKNNELLSDNDRFKTRFDGQTG--TL 1372

Query: 132  LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVS---ETVEH 188
             I+ +   D   Y    RN  GE   S  ++                 + V     T   
Sbjct: 1373 TIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDVKGVEGDEATFNV 1432

Query: 189  KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVD-TFEYRLLREVSFRESITKRYVGE 247
            K  G      E    T ++    G    S DD K   T +   L+++   + I     G+
Sbjct: 1433 KLSGYPSPDIEWYYGTTRIR-DGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGK 1491

Query: 248  SDVQISTEI-DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
               +   E+ +R   P+   K   +P   ++++  +  + V+  G P+P VTW+KNG+ L
Sbjct: 1492 VTQRAELEVKERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVR--GRPKPTVTWWKNGKEL 1549

Query: 307  INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ 366
             +    EI +   + TL            Y L +E              E    SY    
Sbjct: 1550 RDGKHVEIRSGGTYHTL------------YILRSE--------------EEDAGSYKCLA 1583

Query: 367  RSQYITDTQQRETEERIE-ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
            R+     + +R  E ++E +  K  AP+     +   +TE       C V G P P   W
Sbjct: 1584 RND--VGSAERLFEVQVEGVKPKEEAPKLTSQLRSARITESDDFELACDVKGTPDPSYEW 1641

Query: 426  FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
              +D+ ++ D  H     +     L    V LSD G  T   +N  G T     L++++ 
Sbjct: 1642 LKDDKPVKFD-RHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKS 1700

Query: 486  EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD--G 543
            +    P+ +E        E      + +    P   + W      I       +  D   
Sbjct: 1701 KS--KPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEED 1758

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            G  ++ I   +  D   Y+  A N  G T+ RA L
Sbjct: 1759 GTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAEL 1793



 Score = 87.4 bits (207), Expect = 2e-16
 Identities = 114/462 (24%), Positives = 185/462 (40%), Gaps = 38/462 (8%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  +  +EWF +G+ +  ++ +          L++L T   DSGTY   ATN  G A   
Sbjct: 3906 GKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRI 3965

Query: 3136 VKLECV---DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
              L       K K   P F T +  +  + +G    F   V  V  P   I+WY +  P+
Sbjct: 3966 FNLNVTAIAPKEKWSSPIFVTELSPLS-VTEGDYTKFVAHVSGVPLPS--IQWYKDDNPI 4022

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESL 3252
              + RI+T  D   V L I      D G+Y     N+ G   + A ++   + G      
Sbjct: 4023 SSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYG------ 4076

Query: 3253 QPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQ------SAHFEARL 3306
            +P      R++E   G++ +     S  P   +   +  TKL   +      + +   R 
Sbjct: 4077 KPAITQLYRDVEGFDGSESELTVQVSGVPAAEVEWFRGKTKLFPSERSYKIIATNEYGRT 4136

Query: 3307 VPVDDPDLK-----VEWFYNGKKLPHGHRYRTFHDFGIVIL----DILYCYEENSGEYEC 3357
              + D  +K      E+     K     R R F +   ++L      ++ +++    YE 
Sbjct: 4137 GALIDLTVKERLFGPEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYET 4196

Query: 3358 VATNKLGRDSTK-ANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVR-RKDTSVEEE 3415
               +   RDS +  N+   + ++        R   G   +  TL+   VR R+   V+  
Sbjct: 4197 SRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKAVRPRRGNEVQAC 4256

Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT--FC 3473
            K +    T  ++N+  + EG     + R+T    P   VEW+   + +  G R++T    
Sbjct: 4257 KPQ----TSKMANVTAV-EGWKVQLDTRMTGYPVP--IVEWFRGEEKITDGGRYKTARME 4309

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            D G   L IS    EDSG Y   A NN GEA T A + V+GK
Sbjct: 4310 DEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTVKGK 4351



 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 50/192 (26%), Positives = 87/192 (45%), Gaps = 4/192 (2%)

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
            E+ EP+   +V E  AI F  ++ GKP+PT+ WYK  ++++  + F++    D YT    
Sbjct: 2338 ELKEPV---VVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATY 2394

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKT 4742
             A  ED G Y C A N  G+ +    L V  P +    P+  + L+ +++ EG       
Sbjct: 2395 SASAEDAGTYTCEASNKLGKCSRDFNLHVDVPKEQWEAPSFKSQLQPVILEEGGTGVLVG 2454

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            ++  K  PTIQW+++   +      +   +G    ++       D G + C      G+ 
Sbjct: 2455 EVAGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCGEA 2514

Query: 4803 ETSAKLVVKSKT 4814
             + A + V   T
Sbjct: 2515 SSKALVGVNRGT 2526



 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 124/481 (25%), Positives = 189/481 (39%), Gaps = 45/481 (9%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G+ P  T+  K    + EG+   Y+ +   TG    VI W+ +G+ I+A  R++  +   
Sbjct: 182  GKAPTVTSELKPD-KVQEGE--QYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDGT 238

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
               L I   K  D GTY    TN  G    +  LE   K    KP     ++N+E + +G
Sbjct: 239  TSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKP--AKPEVVRKMENVESV-EG 295

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV--LDIAYTQNHDSGEY 3222
              A FE        P  K EW+H+ + +  S+R K  +D       L I+  +  DSG Y
Sbjct: 296  SDAFFEVKFKGYPIP--KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAY 353

Query: 3223 VCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPP 3282
             C A N+ GE   RA +    K   +        L  I E++  Q    +   T + +P 
Sbjct: 354  QCIASNEAGECNLRADLKV--KNKPFAPEFADGDLEPI-EVKEDQAVNVRLTVTGNPKPE 410

Query: 3283 ----KFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
                K  TQ+ D  KL    +       +P    + + ++F      P G   RTF    
Sbjct: 411  VTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASN-PLGSPKRTF-KVT 468

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQ 3398
            +V   +    E  SG        + G    K ++      N  LD       + G  K++
Sbjct: 469  VVPKGVAPVIE--SGLMPLQVRKETG---AKWSV------NTTLD-------DAGEYKVK 510

Query: 3399 TLED--SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456
               +  S+    D +V++ K K P F   + ++  L E E   FE  +     P   VEW
Sbjct: 511  VTNEVGSVTSLADINVQKAKVK-PEFLRKVEDVTAL-ETEQVWFEIPI--QGYPRPIVEW 566

Query: 3457 YWNGKSLKAGSRF--RTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            Y     +K G RF      +     L I     EDSG Y C A N+ G+     ++ V  
Sbjct: 567  YRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNE 626

Query: 3515 K 3515
            K
Sbjct: 627  K 627



 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 131/617 (21%), Positives = 242/617 (39%), Gaps = 51/617 (8%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E S    G  S  + W+ + + +    +             +      D+G+Y C A N+
Sbjct: 1822 EVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNR 1881

Query: 3129 WGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187
             G A  +  +E  V K++ + P FTT ++ I+ + +G++  F C V    +P   + WY 
Sbjct: 1882 VGSATRNFNVEIEVPKARDEAPSFTTTLKPID-VTEGENHTFICRVHARPEPS--VTWYR 1938

Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGV 3247
            N   +    R +T  D     L +   +  D+G+Y C A N  G+ F      C  +  V
Sbjct: 1939 NKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAF------CTAEMTV 1992

Query: 3248 YLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHF--EAR 3305
                ++P      +  E  +G         S  P   +       ++++G       E  
Sbjct: 1993 NKREVKPVIKEVSKTFEVSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGD 2052

Query: 3306 LVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVA------ 3359
               +   D+  +   + K +   +  RT +   +VI +  Y  E    + + +A      
Sbjct: 2053 YHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQN 2112

Query: 3360 --TNKLGRDSTKANLKCTSKENLIL-DSQLPRGMEGGLEKLQ----TLED---------- 3402
              TN   R     +++    + L++ D ++     GGL  L+    TL+D          
Sbjct: 2113 AITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATN 2172

Query: 3403 ---SMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWN 3459
               S  RR    VE  K +APVF   L  +  + EG+N  +  ++     P   VEWY +
Sbjct: 2173 SIGSTSRRIIVDVEALK-EAPVFVSKLRPLF-VTEGDNVSWMCKVAGMPRPT--VEWYRD 2228

Query: 3460 GKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN-- 3517
             + L+A +R++   D     L +S    +D G Y C   N+ G A ++A ++V  K N  
Sbjct: 2229 NQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKP 2288

Query: 3518 IILES----QLPKGMEGTID-KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSEN 3572
             ++E     Q  +G E   D + + L     T    + +  +            +++ E+
Sbjct: 2289 KVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQES 2348

Query: 3573 SSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTC 3632
             + +F+ R+         + W+ +G+ +    R +  +               DAG YTC
Sbjct: 2349 DAINFKVRV--RGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTC 2406

Query: 3633 KATNRHGEATVSCKLQV 3649
            +A+N+ G+ +    L V
Sbjct: 2407 EASNKLGKCSRDFNLHV 2423



 Score = 82.6 bits (195), Expect = 7e-15
 Identities = 54/192 (28%), Positives = 82/192 (42%), Gaps = 4/192 (2%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + ++E    P+  +  +  +  EG   RFD  VTG P P V W+    +I D   +   +
Sbjct: 5631 LNVNEGYSKPEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSSTL 5690

Query: 443  NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS--TL 500
               G  +L I  +   D G+  CVA N+ GET     L+V EK     P+F E     + 
Sbjct: 5691 TSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEKH--YGPEFAEEELDWSK 5748

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
              R+GE   +     G P P + W KDG+ +     + + + G    L I      D   
Sbjct: 5749 TARKGENARITFTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGT 5808

Query: 561  YQCTAQNVAGST 572
            Y C AQ+  G +
Sbjct: 5809 YVCEAQSRLGKS 5820



 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 65/264 (24%), Positives = 110/264 (41%), Gaps = 20/264 (7%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E + A   +     P P ++WY+ +  + +     + T      L IR+  ++D+  +
Sbjct: 2107 VREGQNAITNMTIRARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTY 2166

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
               A N  G+   S  ++V+ +  +       P F    + + VT G  V    KV G  
Sbjct: 2167 ICKATNSIGST--SRRIIVDVEALKEA-----PVFVSKLRPLFVTEGDNVSWMCKVAGMP 2219

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
               V W ++ + ++ D R K+  +    +L + EA  +D G Y CV  NSAG A   AE 
Sbjct: 2220 RPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAEL 2279

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
             V   A K             P++IE + D    EG    F  +  G P P V WY+   
Sbjct: 2280 QVDKKANK-------------PKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSI 2326

Query: 4662 LIKPSKYFQMSRTADEYTLRISEA 4685
             ++  K++      +   ++ S+A
Sbjct: 2327 KVRNEKFYGDDELKEPVVVQESDA 2350



 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 84/341 (24%), Positives = 145/341 (42%), Gaps = 30/341 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            PEF    +  + + EGQ A    ++      S  +EW+     + +  +I      G+  
Sbjct: 2095 PEFEDFDEKRIAVREGQNAITNMTI--RARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYY 2152

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LEI      D+GTY C+ATN  G     + ++ V+  K + P F + ++ +  + +G + 
Sbjct: 2153 LEIRKATLDDAGTYICKATNSIGSTSRRIIVD-VEALK-EAPVFVSKLRPL-FVTEGDNV 2209

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             + C V  +  P   +EWY + QP+R  TR K   D     L ++     D G Y C   
Sbjct: 2210 SWMCKVAGMPRP--TVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVIT 2267

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287
            N  G  F+ A +    K        +P  + K+ ++++++G + +     S  P   +T 
Sbjct: 2268 NSAGSAFSSAELQVDKKAN------KPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTW 2321

Query: 3288 IQDVTKLVEGQSAHFEARL---VPVDDPD-LKVEWFYNGKKLP------HGHRYRTFHDF 3337
             ++  K V  +  + +  L   V V + D +  +    GK +P       G   R    F
Sbjct: 2322 YRNSIK-VRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRF 2380

Query: 3338 GIVILDILYCY------EENSGEYECVATNKLGRDSTKANL 3372
             I     +Y +       E++G Y C A+NKLG+ S   NL
Sbjct: 2381 EIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNL 2421



 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 59/179 (32%), Positives = 76/179 (42%), Gaps = 4/179 (2%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V EG        V G+P P V WF  D Q+  + N+  L        L +   T +DSG 
Sbjct: 3892 VREGCEVSMMANVRGKPAPTVEWF-KDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGT 3950

Query: 463  VTCVARNKSGETAFQCRLNVIE---KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519
               VA N  G       LNV     KE+  +P FV   S L+V EG+     A   G P 
Sbjct: 3951 YKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTELSPLSVTEGDYTKFVAHVSGVPL 4010

Query: 520  PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            P I W KD  PI  N  +R   DG    L I +    D   Y+   +N +GS  + A+L
Sbjct: 4011 PSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKL 4069



 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 112/456 (24%), Positives = 189/456 (41%), Gaps = 51/456 (11%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR--IRTVYAFGM 3105
            PE     +++  + EG  A +E      G      EWF++ K IE S R  I T      
Sbjct: 281  PEVVRKMENVESV-EGSDAFFEVKF--KGYPIPKREWFHDSKKIEPSSRFKITTDDTEQT 337

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTT-HIQNIEGLKDG 3164
              L I   +  DSG Y C A+N+ G+  +   L+   K+K   P F    ++ IE +K+ 
Sbjct: 338  SSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV--KNKPFAPEFADGDLEPIE-VKED 394

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            Q+ +   TV    +P  ++ WY +G  +  + ++K  +      L I     +D G+Y C
Sbjct: 395  QAVNVRLTVT--GNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFC 452

Query: 3225 RAYNKYGEDFTRATINCYGKG-------GVYLESLQPDSLAKIRELESLQGAQQ------ 3271
             A N  G       +    KG       G+    ++ ++ AK     +L  A +      
Sbjct: 453  EASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVT 512

Query: 3272 -QTPSTPSAEP---------PKFITQIQDVTKLVEGQSAHFEARLVPVDD-PDLKVEWFY 3320
             +  S  S            P+F+ +++DVT L E +   FE   +P+   P   VEW+ 
Sbjct: 513  NEVGSVTSLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFE---IPIQGYPRPIVEWYR 568

Query: 3321 NGKKLPHGHRYRTFH--DFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK- 3377
               ++  G R+      +  +  L I     E+SG Y+CVA+N  G+ +   NL    K 
Sbjct: 569  GTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNEKV 628

Query: 3378 ENLILDSQL-PRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGE 3436
                 D ++ P  ++ G E   +LE  +  +    V   K   P+       ++++ + E
Sbjct: 629  VQPEFDKEVKPIEVKHGEEATTSLE--IKGKPKPKVTWYKDLVPLLETRSIQLKSVGD-E 685

Query: 3437 NAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF 3472
            +       TP D+   K E      + KAG+ FR+F
Sbjct: 686  HTLEIINATPDDEGKYKCE-----ATNKAGTAFRSF 716



 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 68/295 (23%), Positives = 115/295 (38%), Gaps = 18/295 (6%)

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            V V     +    +V G     + W K+G+ V+   R +I      YT     A  +D+G
Sbjct: 2343 VVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAG 2402

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y C A N  G+   D    V      D PK Q +A    P     L+  I+ EG     
Sbjct: 2403 TYTCEASNKLGKCSRDFNLHV------DVPKEQWEA----PSFKSQLQPVILEEGGTGVL 2452

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
              ++ GKPLPT+QW K D  +      +         +   EA   D G Y+C+  N  G
Sbjct: 2453 VGEVAGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCG 2512

Query: 4703 RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
              +  A + V +      +  +     +V+ EG  ++F  +I     P ++W      + 
Sbjct: 2513 EASSKALVGVNRGTVGPEI--IEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLT 2570

Query: 4763 ETPDFQMIHEGNNAV----LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +   +++  E N  +    L++     + TG +   A+   G+ +    L V  +
Sbjct: 2571 DGVKYRI--ESNPEIGLYSLVVSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER 2623



 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 8/195 (4%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G  P  TT   DI  I +G+       +  TG+ +  +EWF +GK ++A+HR+   +   
Sbjct: 727  GETPTITTEMTDIQAI-DGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEER 783

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            M+ L     K  D G Y C  +N +G    + +++  D+S   KP   T +++ + +++ 
Sbjct: 784  MIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS--LKPEVITSMRDCDCVEE- 840

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            ++A F C       P+ +IEW+    P+    R     +     L I+  +  D+G Y C
Sbjct: 841  ETASFHCEF--SGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKC 898

Query: 3225 RAYNKYGEDFTRATI 3239
             A N  G+  TRA +
Sbjct: 899  VASNAAGKTTTRAEL 913



 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 87/339 (25%), Positives = 141/339 (41%), Gaps = 49/339 (14%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P+  VEWY     +    +       G   L+I  A  +D GTY+CKATN++G   T+  
Sbjct: 2123 PSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGS--TSRR 2180

Query: 2067 VKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDR 2126
            + VD ++           LK        E P  + +     RP+F+T         EGD 
Sbjct: 2181 IIVDVEA-----------LK--------EAPVFVSK----LRPLFVT---------EGDN 2208

Query: 2127 AHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186
              + C+V  +  P  T++W+ + Q +RA  R++   D    +L +     +D G Y C  
Sbjct: 2209 VSWMCKVAGM--PRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVI 2266

Query: 2187 TNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ-----GHSTRIEV----EEP 2237
            TN  G A ++  L+V    N     +  N ++ +   EA+         R EV       
Sbjct: 2267 TNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSI 2326

Query: 2238 KISPPRFV--TELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITF 2295
            K+   +F    EL+    V E    +F+ +V     P   I +Y +G+ ++   RF I  
Sbjct: 2327 KVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPT--IVWYKDGEMVRDVRRFEIRS 2384

Query: 2296 DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
                 +        EDAG Y+ +A N LG C+   ++ V
Sbjct: 2385 RGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHV 2423



 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 67/252 (26%), Positives = 110/252 (43%), Gaps = 16/252 (6%)

Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021
            S  +R + D   + E P F   ++   VTEG  V     +  +  PT  VEWY + +P++
Sbjct: 2176 STSRRIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLR 2233

Query: 2022 QGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG--LYLDT 2079
               R+K  +D    +L +  A  +D G Y C  TN+ G A +++ ++VD K+     ++ 
Sbjct: 2234 ADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEK 2293

Query: 2080 LDEQRLKKIQELEKYER----PKPIEEEQPGQRPVFLTALTSLENLK------EGDRAHF 2129
            +++ +  +  E     R    P+P          V        + LK      E D  +F
Sbjct: 2294 MNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINF 2353

Query: 2130 ECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNK 2189
            + RV     P  TI W+ +G+ +R   R+                 AED+GTY C+A+NK
Sbjct: 2354 KVRVR--GKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNK 2411

Query: 2190 LGEAVNTCTLKV 2201
            LG+      L V
Sbjct: 2412 LGKCSRDFNLHV 2423



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 62/258 (24%), Positives = 109/258 (42%), Gaps = 16/258 (6%)

Query: 1689 NQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLR 1748
            N +  TS+  R     E + +APVF   ++ + V E     +  ++   G P+  VEW R
Sbjct: 2172 NSIGSTSR--RIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMCKV--AGMPRPTVEWYR 2227

Query: 1749 NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
            +  P+ A  R     D    +L +   + +D G Y C   N  G A +S+ L V  KA+ 
Sbjct: 2228 DNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANK 2287

Query: 1809 QLESQHESALQKIQQLED--SSRYQRREDVEV--------AVNQAPRFITQLNGPTKLSE 1858
                +  + +Q ++  E     R+      EV          N+      +L  P  + E
Sbjct: 2288 PKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQE 2347

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
              + +++ R+   P P   + WY +G++++   R+   +          +   ED+G YT
Sbjct: 2348 SDAINFKVRVRGKPVPT--IVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYT 2405

Query: 1919 CKAINNLGQAVSSIRLNV 1936
            C+A N LG+      L+V
Sbjct: 2406 CEASNKLGKCSRDFNLHV 2423



 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 57/229 (24%), Positives = 105/229 (45%), Gaps = 10/229 (4%)

Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
            S   TG  +  I W+ +G+ ++ + RI       +  L IL  K  D+GTY+C A N+ G
Sbjct: 2856 SFTVTGSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIG 2915

Query: 3131 QAEISVKLE-CVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG 3189
             A  S +++    K KG+ P F+  ++ I  +++  S    C V     P  +I+W  NG
Sbjct: 2916 AAYRSFEVDVTAPKVKGEAPSFSLELRPIAAIEEFDS-KLICHV--SGKPKPQIKWTKNG 2972

Query: 3190 QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYL 3249
            +P+    R++T  D     L I    + D+G Y C A N  G   + A +       V  
Sbjct: 2973 KPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALT------VSR 3026

Query: 3250 ESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQ 3298
             +++P    K+ ++++ +G + +     +  P   +   +  + + EG+
Sbjct: 3027 RNMRPLITHKLHDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGR 3075



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 137/644 (21%), Positives = 238/644 (36%), Gaps = 82/644 (12%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
            P+  V WY+D R +    +             + ++ A DAGSY   A N++G A    +
Sbjct: 1831 PSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVGSATRNFN 1890

Query: 860  IRV--------AARSTVTA---DLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQK 908
            + +        A   T T    D+   E   +I +                  VP+   +
Sbjct: 1891 VEIEVPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPSVTWYRNKNEIVPDGRSR 1950

Query: 909  PEFKTP----IKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVE-ASSRITTFFN 963
              F       I   I IK+ G     A   PIG +    E   + R V+     ++  F 
Sbjct: 1951 TTFDGETYKLILQDIKIKDAGQYECIAS-NPIGKAFCTAEMTVNKREVKPVIKEVSKTFE 2009

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES-QHPGGLEKIQY 1022
                      V V      T   Y+   +        +  + D    S +  G      Y
Sbjct: 2010 VSEGGTASIEVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAASY 2069

Query: 1023 LEDASRYSKRT--EEEVKITQK---PRFLGPLKGTNKIVEGQSA--HFEARVEPQSDLTM 1075
               A   + RT    ++ IT++   P F    +    + EGQ+A  +   R  P  D   
Sbjct: 2070 KCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTIRARPSPD--- 2126

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             VEWY     + S  +I      G   L+I     +D+G Y   A N+ G        + 
Sbjct: 2127 -VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIG--------ST 2177

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
              R  +D  ++                  P++    +SK +P+F         V+EG N+
Sbjct: 2178 SRRIIVDVEALKEA---------------PVF----VSKLRPLF---------VTEGDNV 2209

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
               C++  M  PT  VEW+ + + +   +R+K  +D    +L +  A   D G Y     
Sbjct: 2210 SWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVIT 2267

Query: 1256 NHLGSAHTSAIVRVIERSD---IVTDTQNEQAIEQIQLLEDAARRTKQVREDIT------ 1306
            N  GSA +SA ++V ++++   ++    + Q +E  +   D  R +   R ++T      
Sbjct: 2268 NSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFD-VRFSGLPRPEVTWYRNSI 2326

Query: 1307 VMQAPQF---SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
             ++  +F         +   E   ++ + R++  G     + W+ +G+ ++   RF    
Sbjct: 2327 KVRNEKFYGDDELKEPVVVQESDAINFKVRVR--GKPVPTIVWYKDGEMVRDVRRFEIRS 2384

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407
              D       S   ED+G YTC+A+N+LG+      L V   K+
Sbjct: 2385 RGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHVDVPKE 2428



 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 56/187 (29%), Positives = 86/187 (45%), Gaps = 11/187 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P FT   + I DI EG    +   +  TG    V+EW+ + + +   HR+RT Y+ G VV
Sbjct: 5544 PAFTAPLQHI-DILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRT-YSDGRVV 5599

Query: 3108 LEILG-TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            + +L  T  +D+G + C   N  G    S  L  V++    KP     ++ IE  + G+ 
Sbjct: 5600 ILLLRQTNISDAGVFKCVLRNDLGTVASSASLN-VNEGY-SKPEINEKLKKIEAFEGGE- 5656

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI-KTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            A F+  V     P  +++WY     +    R   T++  G   L I   +  D G Y C 
Sbjct: 5657 ARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYGCV 5714

Query: 3226 AYNKYGE 3232
            A N+YGE
Sbjct: 5715 AVNEYGE 5721



 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 80/349 (22%), Positives = 140/349 (40%), Gaps = 15/349 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   +EWY + + L   +R+K+  D    +L L +   +D G+Y C   N  G AF+S+ 
Sbjct: 2219 PRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAE 2278

Query: 3001 VYCTSKDN---LIERTQHPKGTEGLEKIQNLEDS--LRKEPGQQPDDDTGRPPEF--TTV 3053
            +    K N   +IE+    +  EG E   ++  S   R E     +    R  +F     
Sbjct: 2279 LQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDE 2338

Query: 3054 FKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGT 3113
             K+ V + E    +++  +   G     I W+ +G+ +    R        +        
Sbjct: 2339 LKEPVVVQESDAINFKVRV--RGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSA 2396

Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172
               D+GTY+C A+NK G+      L   V K + + P F + +Q +  L++G +      
Sbjct: 2397 SAEDAGTYTCEASNKLGKCSRDFNLHVDVPKEQWEAPSFKSQLQPVI-LEEGGTGVLVGE 2455

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            V     P   I+W  +  P+    R++   D     +        D G Y C   N+ GE
Sbjct: 2456 V--AGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCGE 2513

Query: 3233 DFTRATINCYGKGGVYLESLQ-PDSLAKIRELESLQGAQQQTPSTPSAE 3280
              ++A +    +G V  E ++ P  L  +   +S    + +   TP  E
Sbjct: 2514 ASSKALVG-VNRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVE 2561



 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 58/252 (23%), Positives = 109/252 (43%), Gaps = 15/252 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            PEF   +KD +D  +GQ  +    +   G     I W  +G+ +  +  ++      +  
Sbjct: 922  PEFED-WKDTIDALDGQDVNISTWV--RGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHG 978

Query: 3108 LEILGTKTTDSGTYSCRATNKWG--QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            L +      D+G Y+CRA N  G    ++++ +E + K KG  P F + ++ IE + +G 
Sbjct: 979  LVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEALQK-KGDTPTFMSKLEPIE-ITEGD 1036

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                 C V     P+  ++W+ +   ++ S R K   D     L +   +  D G Y C 
Sbjct: 1037 DFQLSCNVTGRPQPE--VQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDDDGVYKCV 1094

Query: 3226 AYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFI 3285
              N +G   ++A +       V  + L+P+ L K+ ++ +++G +        A P   I
Sbjct: 1095 VTNNFGSVSSKADVT------VLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPEI 1148

Query: 3286 TQIQDVTKLVEG 3297
                  TK+ +G
Sbjct: 1149 EWYLGATKITDG 1160



 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 63/247 (25%), Positives = 111/247 (44%), Gaps = 17/247 (6%)

Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
            DVE A+ +AP F+++L  P  ++EG +  + C++   P P   VEWY + + L++  R++
Sbjct: 2184 DVE-ALKEAPVFVSKLR-PLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWK 2239

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
               D    +L +     +D G Y C   N+ G A SS  L V  K +  +  +  + ++ 
Sbjct: 2240 MDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQT 2299

Query: 1955 IQYLED--DSRYKRAVQDD------SFVVEKPQF--GKPIKN-AEVTEGHPVHLEATLTP 2003
            ++  E   D R+    + +      S  V   +F     +K    V E   ++ +  +  
Sbjct: 2300 VEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVR- 2358

Query: 2004 VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
               P   + WY +G  V+   RF+              A AED GTY C+A+N +G+   
Sbjct: 2359 -GKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSR 2417

Query: 2064 TSSVKVD 2070
              ++ VD
Sbjct: 2418 DFNLHVD 2424



 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 122/526 (23%), Positives = 202/526 (38%), Gaps = 46/526 (8%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            EI +   +   P FT  +K  IDV EG    F CRV    +P+  + W+ N        R
Sbjct: 1892 EIEVPKARDEAPSFTTTLKP-IDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGR 1948

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
              T  D     L +  I  +DAG+Y C A+N  G      K  C+A+  +      P   
Sbjct: 1949 SRTTFDGETYKLILQDIKIKDAGQYECIASNPIG------KAFCTAEMTVNKREVKPVIK 2002

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP---- 3859
               K  E+  G  +     E  VS  P    +    +    +G RF+   E         
Sbjct: 2003 EVSKTFEVSEGGTASI---EVKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIR 2059

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             +  +   + K +   +  RT Y    V  +  Y    +  +    AV +     T  TI
Sbjct: 2060 DVGDQAAASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTI 2119

Query: 3920 SCKKLPDI-------ILQNQVPRGMKRSEALTQME---ATIK-------KYTSEVYLTED 3962
              +  PD+       +L +     +K    L  +E   AT+        K T+ +  T  
Sbjct: 2120 RARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSR 2179

Query: 3963 DLY-DVDK-KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKN 4020
             +  DV+  K+ P FV++++    + E +   + C++A  G P   VEW+ + +PL    
Sbjct: 2180 RIIVDVEALKEAPVFVSKLRP-LFVTEGDNVSWMCKVA--GMPRPTVEWYRDNQPLRADT 2236

Query: 4021 RFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGIVYDSQL 4077
            R+   +D    ++       +D G Y C  TN  G   + A   V K   KP ++     
Sbjct: 2237 RWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMND 2296

Query: 4078 PKHMKSIEKIREMEASWQVTPEQVVEES--KARCPPVFVS--LPDAVTVEEGEWARFCCR 4133
             + ++  E   ++  S    PE     +  K R    +    L + V V+E +   F  R
Sbjct: 2297 VQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVR 2356

Query: 4134 VTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTG 4178
            V G P P ++W  +G  + +  R+++   G +Y F        D G
Sbjct: 2357 VRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAG 2402



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 83/395 (21%), Positives = 142/395 (35%), Gaps = 38/395 (9%)

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477
            +P  V E  +        G+P P ++W+++   + N+ +  +        L + +    D
Sbjct: 3888 EPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQAD 3947

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            S  +  VA N  G+A    NL V     + +     P F      ++VT G   +    V
Sbjct: 3948 SGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWS--SPIFVTELSPLSVTEGDYTKFVAHV 4005

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
            +G     + W K+   +  + R +   +     LLI +   +D G+Y+ V  N +G A  
Sbjct: 4006 SGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATS 4065

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             A+  V             +     P I +  +D    +G   E + ++ G P   V+W+
Sbjct: 4066 SAKLSV-------------REEYGKPAITQLYRDVEGFDGSESELTVQVSGVPAAEVEWF 4112

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            +G   + PS                       E  YK +A N  GR      L V +   
Sbjct: 4113 RGKTKLFPS-----------------------ERSYKIIATNEYGRTGALIDLTVKERLF 4149

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777
                         +V E   A     +    +P + W ++G  + ET    M    +   
Sbjct: 4150 GPEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQY 4209

Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
            L I     +D GT+ C A +  G    S  L VK+
Sbjct: 4210 LNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKA 4244



 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 60/233 (25%), Positives = 102/233 (43%), Gaps = 16/233 (6%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E S +  G     ++W+  GK +  S  +    +     + I   K   SG Y C ATN 
Sbjct: 5461 ELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEATNS 5520

Query: 3129 WGQAEISVKLEC---VDKSKGQKPRFTTHIQNIEGLKDGQSAHF--ECTVVPVDDPDMKI 3183
             G A     L     V   +   P FT  +Q+I+ L +G +  F  E T VPV      +
Sbjct: 5521 NGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDIL-EGDTTRFIGEITGVPVP----VV 5575

Query: 3184 EWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
            EWY + +P+    R++T SD   V+L +  T   D+G + C   N  G   + A++N   
Sbjct: 5576 EWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLN--- 5632

Query: 3244 KGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
               V     +P+   K++++E+ +G + +     +  PP  +   +  TK+ +
Sbjct: 5633 ---VNEGYSKPEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITD 5682



 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 60/242 (24%), Positives = 107/242 (44%), Gaps = 15/242 (6%)

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121
            +GQ+   +A ++P   + ++  W+ +G  +E S R+          + +      DSG Y
Sbjct: 4370 KGQMVSVKA-IVPAHPKQVI--WYKDGIRLEDSRRVNLRSVGERYYVVVPSASFEDSGIY 4426

Query: 3122 SCRATNKWGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             C  T++         + +E V KS    P F + +++++  +D +SA F C V     P
Sbjct: 4427 KCETTSEKETTSQLFDIHIEDVCKS-ALAPGFKSALRSLDVTED-ESAEFRCEVS--GSP 4482

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
              +I+W+ N QP+   +RI T SD     L I      D+G Y C A N  G   + A +
Sbjct: 4483 APRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADL 4542

Query: 3240 NCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQS 3299
            N      V    ++P  + ++RE+ ++ G +          P   I   +D+T+L+    
Sbjct: 4543 N------VSHCRMKPTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGR 4596

Query: 3300 AH 3301
             H
Sbjct: 4597 FH 4598



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 59/277 (21%), Positives = 110/277 (39%), Gaps = 12/277 (4%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           + G A+F+  + G P P V W + K  +    K+ +   +  G  SL+IK +   D G Y
Sbjct: 4   ESGEARFDVTIEGYPKPTVEWYQGKNKIGSSGKHKI-LEDDDGKCSLIIKDLTKDDAGAY 62

Query: 145 TCTARNQYGEAI----CSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQ 200
            C A N  G+       SV  +                +   S  ++    G        
Sbjct: 63  KCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVW 122

Query: 201 SRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES--DVQISTEIDR 258
            +  + +  T   D  STDD    +       +    +   K  +G S  D  ++ ++  
Sbjct: 123 YKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKG 182

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
                  P +  + +  K+QEG   +F   ++G P+P ++W+K+GQ +    + +     
Sbjct: 183 -----KAPTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDG 237

Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
             +TL +++ ++ D G Y +   N  G I ++  L V
Sbjct: 238 TTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEV 274



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 55/202 (27%), Positives = 92/202 (45%), Gaps = 12/202 (5%)

Query: 4623 PEIIEP--LKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYT 4679
            PE IE      KIV E      +  ++G P P V W+K G +L + S+    SR + +Y 
Sbjct: 4151 PEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQY- 4209

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRV--TVAAKLKVTQPDQADNLPALTP----LRDIVVY 4733
            L I    P+D G Y C A +  G    +    +K  +P + + + A  P    + ++   
Sbjct: 4210 LNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKAVRPRRGNEVQACKPQTSKMANVTAV 4269

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV--LLIGNTYEEDTGTF 4791
            EG   Q  T++T    P ++W R    I +   ++     +  +  L+I +   ED+G++
Sbjct: 4270 EGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSY 4329

Query: 4792 TCRATTAAGQVETSAKLVVKSK 4813
               A+   G+  T A+L VK K
Sbjct: 4330 RAVASNNLGEATTLAELTVKGK 4351



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 53/222 (23%), Positives = 96/222 (43%), Gaps = 13/222 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+     ++ +++ EG+  + + ++  TG     + W+ +GK +  +  I          
Sbjct: 88   PQIKEKEQEPIEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF 145

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I      DSG Y C A NK G +     +    K KG+ P  T+ ++  + +++G+  
Sbjct: 146  LSIPKATPNDSGKYKCEAKNKIGTSARDFDVNV--KVKGKAPTVTSELKP-DKVQEGEQY 202

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             F C V     P   I WY +GQP++   R+K   D     L I   +  D G Y     
Sbjct: 203  KFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEIT 260

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269
            N  G   + A +       V  +  +P+ + K+  +ES++G+
Sbjct: 261  NDLGSISSTADLE------VTPKPAKPEVVRKMENVESVEGS 296



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 65/282 (23%), Positives = 121/282 (42%), Gaps = 12/282 (4%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           +P I E+  +     +G +   +  + G P P V W +   PL +     ++  + +  +
Sbjct: 87  APQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYFL 146

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAI--CSVYIQPEGXXXXXXXXXXXXXYRHVSETVE 187
           S  I +  P D G+Y C A+N+ G +     V ++ +G                V E  +
Sbjct: 147 S--IPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPD---KVQEGEQ 201

Query: 188 HKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGE 247
           +K         +      K       D    D F   T    L+++V   +  T +    
Sbjct: 202 YKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFD-GTTSTLLIKDVKQDDKGTYKVEIT 260

Query: 248 SDV-QISTEIDRSLGP-VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
           +D+  IS+  D  + P  + P++ +K  N +  EG+DA F+V+  G P P+  WF + ++
Sbjct: 261 NDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKK 320

Query: 306 LINSNKHEIIT--THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           +  S++ +I T  T   ++L + + +  DSG Y  +A N  G
Sbjct: 321 IEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAG 362



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 57/248 (22%), Positives = 97/248 (39%), Gaps = 10/248 (4%)

Query: 764  EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
            E   + P F+  L+ L  + EG N  +  ++  +  PT  VEWY+D +P+ A +R    F
Sbjct: 2186 EALKEAPVFVSKLRPLF-VTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDF 2242

Query: 824  NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRRYIEK 883
            +    SL +     +D G Y     N  G A S+A ++V  ++     +      + +E 
Sbjct: 2243 DGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEG 2302

Query: 884  TXXXXXXXXX-----XXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGD 938
            T                      +    +K      +K+ + ++E    +F+ R+   G 
Sbjct: 2303 TEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVR--GK 2360

Query: 939  STLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSAN 998
                + W KDG  V    R               S +  DAG YTC A N +G+ +   N
Sbjct: 2361 PVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFN 2420

Query: 999  LTIVTKKD 1006
            L +   K+
Sbjct: 2421 LHVDVPKE 2428



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 66/286 (23%), Positives = 110/286 (38%), Gaps = 16/286 (5%)

Query: 80   NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPG 139
            N    +G   + + ++ G P P+V W R +  + +  +Y     E  G  SL+I  +   
Sbjct: 4265 NVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLE 4324

Query: 140  DEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTE 199
            D G Y   A N  GEA     +  +G                 S     K          
Sbjct: 4325 DSGSYRAVASNNLGEATTLAELTVKGKHFARELEEGGCH----SRLTFRKGQMVSVKAIV 4380

Query: 200  QSRQTQKVAYTNG---TDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEI 256
             +   Q + Y +G    D    +   V    Y ++   SF +S   +    S+ + ++++
Sbjct: 4381 PAHPKQVIWYKDGIRLEDSRRVNLRSVGERYYVVVPSASFEDSGIYKCETTSEKETTSQL 4440

Query: 257  -DRSLGPVS----PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311
             D  +  V      P      R+  + E   A+F+ ++SG+P PR+ WF N Q +  S  
Sbjct: 4441 FDIHIEDVCKSALAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWFMNDQPV--SRD 4498

Query: 312  HEIITTHNHTT--LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
              IIT+ +     L +      D+G Y  LA N NG   ++  L V
Sbjct: 4499 SRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 64/225 (28%), Positives = 93/225 (41%), Gaps = 10/225 (4%)

Query: 3009 LIERTQHPKGTEGLEKIQNLEDSLRKEPGQ-QPDDDTGRPPEFTTVFKDIVDISEGQIAH 3067
            L  +++H  GT   E    L ++  K   Q Q  +   + P F        +  EG +  
Sbjct: 5210 LFTKSEHA-GTYSCEATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLLP-QNAREGDVVK 5267

Query: 3068 YEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATN 3127
            +   +  TG     IEW  +G ++E+  R+ T Y      L I      DSG Y C   N
Sbjct: 5268 FSCKV--TGYPEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKN 5325

Query: 3128 KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187
              G A  S +L  V   K Q+PR + +++ +     G+ A FE T+     P  KI WY 
Sbjct: 5326 NSGWASSSAEL--VVGGKTQRPRLSDNMKELFATVGGE-ARFEVTMKATPKP--KICWYK 5380

Query: 3188 NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            +   +R   R     + G   L I   Q  DSG Y   A NK G+
Sbjct: 5381 DEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVASNKAGK 5425



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 49/155 (31%), Positives = 85/155 (54%), Gaps = 15/155 (9%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLI--PVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            +AP F++ ++ I   E     F+++LI    G PK +++W +NG P+E+  RL T +D G
Sbjct: 2933 EAPSFSLELRPIAAIEE----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYD-G 2987

Query: 1767 YVA-LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
             VA L++  V+ +D+GTY C A N  G  V+SS     S+ +++    H     K+  ++
Sbjct: 2988 IVAYLSIWQVSHDDAGTYECIASNAAG-TVSSSAALTVSRRNMRPLITH-----KLHDMK 3041

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQ 1860
                 + R D+EV  + +P  +    GP+ +SEG+
Sbjct: 3042 AYEGKEARFDIEVTGHPSPT-VEWFKGPSGISEGR 3075



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 145/628 (23%), Positives = 229/628 (36%), Gaps = 103/628 (16%)

Query: 2777 ISH-LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSL 2833
            I+H L+++   EG    F+  V     PT  +EWF     +  G RY+  S  +    SL
Sbjct: 3033 ITHKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEEQGKHSL 3090

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             ++    +D GIY C A                         Q+  GKA   A+      
Sbjct: 3091 IVSDLNADDDGIYKCVA-------------------------QNLAGKASTRAMLDV--- 3122

Query: 2894 RLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKV 2953
             +A+   P   + E PKP  I+    E Q++          V  +  P   +EW+ +GK 
Sbjct: 3123 -IARDFGPEFDEEESPKPV-IVNEGEEAQMM----------VSVRGRPKAVVEWFKDGKF 3170

Query: 2954 LEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK-DNLIER 3012
            L    R  + S      L +  V   D G Y C A +  G +  S T   + K     ++
Sbjct: 3171 LYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRS--SRTFDLSVKVPKPKDK 3228

Query: 3013 TQHPKGTEGLEKIQNLEDSLRK-------EPGQQPD---DDTGRPPE--FTTVFKDIV-- 3058
               P  +  L  ++ LE    K       EP    +   DDT    E  F T F   V  
Sbjct: 3229 WSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCM 3288

Query: 3059 ------DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILG 3112
                  D  E   A  EA +   G     +EWF     +    R R      +  L I  
Sbjct: 3289 LVFRKTDSFECSEARLEAHV--AGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISN 3346

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECT 3172
                D+G Y   ATN+ G     V L   ++  G +      + N +  K G   +   T
Sbjct: 3347 LHMEDTGPYKIIATNEHGSTGSVVDLTVKERLFGPEFLEEEGVWN-KVAKAGGFVNISFT 3405

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            +    +P   + WY +G  +  +TR+   S      ++I      D+G YVC A ++ G 
Sbjct: 3406 LK--GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGT 3463

Query: 3233 DFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVT 3292
                 T+                      ++ S+ G +++  S         I Q  +  
Sbjct: 3464 AIRSCTLEI--------------------KVPSMGGPEEKKIS------KALIGQGDNDV 3497

Query: 3293 KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH--DFGIVILDILYCYEE 3350
            + VEG    F+ R+     P   VEW+    KL    +Y+     + G+  L +    ++
Sbjct: 3498 QAVEGWKVQFQTRITGYPYP--HVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKD 3555

Query: 3351 NSGEYECVATNKLGRDSTKANLKCTSKE 3378
            + G Y+C+ATN  G  + + NL    K+
Sbjct: 3556 DIGTYKCLATNSAGSSACRINLDVKDKQ 3583



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 51/209 (24%), Positives = 87/209 (41%), Gaps = 10/209 (4%)

Query: 371  ITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR 430
            + D     +   + +S   + P FV+  ++     G    F  RV G P P++ W+ +  
Sbjct: 4530 VNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDIT 4589

Query: 431  QIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489
            ++ +    +  ++E G+ + L I NV   DSG   C+  N  G+    CR  ++ + +  
Sbjct: 4590 RLIN--RGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGKET--CRSQLVVEAEEF 4645

Query: 490  APKFVERFSTLNV----REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIHTDGG 544
            AP F E      V    R+   V L A   G+P P + W KD   +  + + L + +   
Sbjct: 4646 APFFPEDEGQGAVPVVTRQDSEVELGAVVRGSPKPEVAWYKDDEDVATDADGLDVGSRDN 4705

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
               L   R    D   Y+C A N  G  +
Sbjct: 4706 VYFLRFARPSVKDGGLYKCVATNEHGEAS 4734



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 57/214 (26%), Positives = 93/214 (43%), Gaps = 13/214 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG--QAEISVKLE 3139
            + W+ +G  I  S  ++      +  L IL TK+  +GTYSC AT+K G   A+  V+++
Sbjct: 5181 VVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAKFDVQIQ 5240

Query: 3140 CVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199
              + +  + P F   +   +  ++G    F C V    +P+  IEW  +G  M    R+ 
Sbjct: 5241 APEAAP-KAPAFLKQLLP-QNAREGDVVKFSCKVTGYPEPE--IEWTRDGVSMESDERVT 5296

Query: 3200 TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAK 3259
            T  D     L I    + DSG Y C   N  G   + A +   GK      + +P     
Sbjct: 5297 TWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK------TQRPRLSDN 5350

Query: 3260 IRELESLQGAQQQTPSTPSAEP-PKFITQIQDVT 3292
            ++EL +  G + +   T  A P PK      ++T
Sbjct: 5351 MKELFATVGGEARFEVTMKATPKPKICWYKDEIT 5384



 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 63/230 (27%), Positives = 98/230 (42%), Gaps = 12/230 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F +    L ++E  +  + C++  +   +  VEW+ + +PL   +R K   D     L
Sbjct: 2192 PVFVSKLRPLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSL 2249

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV--KGRQGIILEPQLPSHFKSGTESIQKL 3675
             +     +D G+Y C  TN  G A  S +LQV  K  +  ++E         GTE+   +
Sbjct: 2250 FLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDV 2309

Query: 3676 EETLHKREEIT--IEDEKPNPPRF--TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731
              +   R E+T      K    +F    E+K+ + V E   ++F  RV   G P   I W
Sbjct: 2310 RFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVR--GKPVPTIVW 2367

Query: 3732 FHNGRPFATGSRVHTLNDFGFIALDIDY-IYARDAGEYTCRATNKWGSAT 3780
            + +G       R   +   G I     Y   A DAG YTC A+NK G  +
Sbjct: 2368 YKDGE-MVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCS 2416



 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 88/346 (25%), Positives = 133/346 (38%), Gaps = 38/346 (10%)

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY--AFGMVVLEILGTKTTDSG 3119
            EG+ A ++  +  TG  S  +EWF     I    R + +     G   L +      D G
Sbjct: 3044 EGKEARFDIEV--TGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDG 3101

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL-KDGQSAHFECTVVPVDD 3178
             Y C A N  G+A     L+ + +  G  P F         +  +G+ A    +V     
Sbjct: 3102 IYKCVAQNLAGKASTRAMLDVIARDFG--PEFDEEESPKPVIVNEGEEAQMMVSVR--GR 3157

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRAT 3238
            P   +EW+ +G+ +  S R+   S      L I +    D G Y C A +  G       
Sbjct: 3158 PKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRTFD 3217

Query: 3239 INCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKL---- 3294
            ++          SL P   +K+R LE+L+G + +     S EP   +   +D T +    
Sbjct: 3218 LSVKVPKPKDKWSL-PAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHED 3276

Query: 3295 --------------------VEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334
                                 E   A  EA +  V  P   VEWF    KL  G RYR  
Sbjct: 3277 RFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRP--TVEWFLGSAKLCDGERYRLE 3334

Query: 3335 HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
                +  L I   + E++G Y+ +ATN+ G  ST + +  T KE L
Sbjct: 3335 QTDNLYTLVISNLHMEDTGPYKIIATNEHG--STGSVVDLTVKERL 3378



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 118/510 (23%), Positives = 196/510 (38%), Gaps = 108/510 (21%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR--TSNDFGFAALDILTVYGEDSG 1915
            EG  + ++ RI  +P P   VEW++  + L  G +YR  ++ + G  +L +  V  + +G
Sbjct: 2542 EGNDSRFDVRIRGHPTPE--VEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTG 2599

Query: 1916 EYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVV 1975
             Y   A N  G+A + + L V  +            L   ++LEDD  + + V+   FV 
Sbjct: 2600 HYRIVASNEHGKAQALLDLTVNER------------LYAPEFLEDDGEWSKVVRKGGFV- 2646

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR--FKTTYDFG 2033
                                    T T + +P   V WY +G  +    R   ++  D  
Sbjct: 2647 ----------------------NITFTLMGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQ 2684

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEK 2093
            Y   +I +   EDTGTY+C+A N +G +  + ++++  K    +D+ D +          
Sbjct: 2685 Y--CNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEI--KEPKSVDSTDTR---------- 2730

Query: 2094 YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR 2153
                       PGQ  + +      E +  G      C V       + I+WF     +R
Sbjct: 2731 ----------APGQL-IPVKHKFDFEGVPGGKA---RCDVLVKKSDIIDIEWFRGTNMLR 2776

Query: 2154 AGHRYR--TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
             G +Y+   + D   ++L +     ED+GTY C      G+        + G  +I    
Sbjct: 2777 DGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTT------IRGELHIKEKQ 2830

Query: 2212 QHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHD 2271
            Q P  L++             +V + K S P+   E+  +  V    T H          
Sbjct: 2831 QAPLFLDE-------------KVSQEKFSLPQ-GQEMNKSFTVTGSPTPH---------- 2866

Query: 2272 PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS 2331
                I +Y +G+ L    R  I        L I +  PEDAG Y+ +A N +G    +  
Sbjct: 2867 ----ITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFE 2922

Query: 2332 MTVTA---KGSIISESQRPEGLEKIRELES 2358
            + VTA   KG   S S     +  I E +S
Sbjct: 2923 VDVTAPKVKGEAPSFSLELRPIAAIEEFDS 2952



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 77/326 (23%), Positives = 138/326 (42%), Gaps = 40/326 (12%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P  +   K++     G+ A +E ++  T    +   W+ +  T+ +  R       G+  
Sbjct: 5345 PRLSDNMKELFATVGGE-ARFEVTMKATPKPKIC--WYKDEITLRSRDRYTMKEEDGIYT 5401

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   + +DSGTY   A+NK G+      LE ++K+    P F    + +E +   +  
Sbjct: 5402 LIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKTVA--PEFPDR-ETLEQVVGVEGR 5458

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV-VLDIAYTQNHDSGEYVCRA 3226
              E + V    P   ++WY  G+ + H+++  TVS  G    + I   ++  SG Y C A
Sbjct: 5459 EVELSTVVKGLPRPSVKWYKEGK-LLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEA 5517

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
             N  G       +N   +     + + P   A ++ ++ L+G           +  +FI 
Sbjct: 5518 TNSNGTAHRDFVLNIQAQVPAE-QWVAPAFTAPLQHIDILEG-----------DTTRFIG 5565

Query: 3287 QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILY 3346
            +I  V               VPV      VEW+ + + +   HR RT+ D  +VIL +  
Sbjct: 5566 EITGVP--------------VPV------VEWYRDDRPVTRDHRLRTYSDGRVVILLLRQ 5605

Query: 3347 CYEENSGEYECVATNKLGRDSTKANL 3372
                ++G ++CV  N LG  ++ A+L
Sbjct: 5606 TNISDAGVFKCVLRNDLGTVASSASL 5631



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 54/200 (27%), Positives = 87/200 (43%), Gaps = 14/200 (7%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLI--PTGDQSMVIEWFYNGKTIEASHRIRTVYA 3102
            G  P F+   + I  I E     +++ LI   +G     I+W  NGK +E+  R+RT Y 
Sbjct: 2932 GEAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYD 2986

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
              +  L I      D+GTY C A+N  G    S  L      +  +P  T  + +++   
Sbjct: 2987 GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTV--SRRNMRPLITHKLHDMKAY- 3043

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS--DFGFVVLDIAYTQNHDSG 3220
            +G+ A F+  V     P   +EW+     +    R + +S  + G   L ++     D G
Sbjct: 3044 EGKEARFDIEV--TGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDG 3101

Query: 3221 EYVCRAYNKYGEDFTRATIN 3240
             Y C A N  G+  TRA ++
Sbjct: 3102 IYKCVAQNLAGKASTRAMLD 3121



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 91/414 (21%), Positives = 166/414 (40%), Gaps = 51/414 (12%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G   +    ++G P P V W  K+  L+  +K ++  +       + I        G Y
Sbjct: 5456 EGREVELSTVVKGLPRPSVKWY-KEGKLLHTSK-ALTVSTSGDTHYVWIPSAKHEHSGRY 5513

Query: 145  TCTARNQYGEAICS--VYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSR 202
             C A N  G A     + IQ +               +H+ + +E     T  +  E + 
Sbjct: 5514 RCEATNSNGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHI-DILEGD---TTRFIGEITG 5569

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFE-----YRLLREVSFRESITKRYVGESD---VQIST 254
                V      D   T D ++ T+        LLR+ +  ++   + V  +D   V  S 
Sbjct: 5570 VPVPVVEWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSA 5629

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE- 313
             ++ + G  S P+I +K +  +  EG +A+F + ++G P PRV W++   ++ + N++  
Sbjct: 5630 SLNVNEG-YSKPEINEKLKKIEAFEGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSS 5688

Query: 314  IITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
             +T+    +L +R  ++ D G Y        GC+  + Y      T S V          
Sbjct: 5689 TLTSDGMASLTIRKIRQEDGGLY--------GCVAVNEY----GETTSIVD--------- 5727

Query: 374  TQQRETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQ 431
                     + + EK   P+F +   D   T  +G+  R    V+G P P+V W+  D  
Sbjct: 5728 ---------LHVGEKHYGPEFAEEELDWSKTARKGENARITFTVSGNPRPDVVWY-KDGM 5777

Query: 432  IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
            +  D  H  + +      L I  +T  D+G   C A+++ G++     L V E+
Sbjct: 5778 LLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKVEEQ 5831



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 65/247 (26%), Positives = 104/247 (42%), Gaps = 29/247 (11%)

Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVN 1776
            ++ I V E+QA +   RL   G+PK  V W ++G  +  + +L          L++   +
Sbjct: 386  LEPIEVKEDQAVN--VRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKAS 443

Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSKA----------SLQLESQHESALQKIQQLED 1826
              D G Y C A N LG    +  + V  K            LQ+  +  +       L+D
Sbjct: 444  TNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDD 503

Query: 1827 SSRYQRREDVEVA---------VNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874
            +  Y+ +   EV          V +A   P F+ ++   T L E +   +E  I+ YP P
Sbjct: 504  AGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQGYPRP 562

Query: 1875 NMRVEWYFNGKVLQSGHRYRTSN--DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
               VEWY     ++ G R+  S   +    +L I     EDSG Y C A N+ G+  + +
Sbjct: 563  I--VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALL 620

Query: 1933 RLNVQSK 1939
             L+V  K
Sbjct: 621  NLDVNEK 627



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 50/180 (27%), Positives = 76/180 (42%), Gaps = 9/180 (5%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAF-GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            +EW+     I +S + + +    G   L I      D+G Y C ATN  GQ  +   L  
Sbjct: 22   VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRGDLSV 81

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
              K K   P+     Q    + +G+S + + T+     P+  + WY +G+P+R +  I  
Sbjct: 82   --KEKQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPE--VVWYKDGKPLRKTKSIDL 137

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG---EDFTRATINCYGKGGVYLESLQPDSL 3257
             S      L I     +DSG+Y C A NK G    DF    +   GK       L+PD +
Sbjct: 138  KSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFD-VNVKVKGKAPTVTSELKPDKV 196



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 121/542 (22%), Positives = 203/542 (37%), Gaps = 104/542 (19%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F      P ++ E Q+ +    +   P P   V WY +G  L    + +        
Sbjct: 378  APEFADGDLEPIEVKEDQAVNVRLTVTGNPKPE--VTWYKDGTQLHDTKKLKLKATGDVH 435

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK------ESIIRDSQ---HESALE 1953
             L I      D G+Y C+A N LG    + ++ V  K      ES +   Q      A  
Sbjct: 436  ELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKW 495

Query: 1954 KIQY-LEDDSRYKRAVQDDSFVVE------------KPQFGKPIKNAEVTEGHPVHLEAT 2000
             +   L+D   YK  V ++   V             KP+F + +++    E   V  E  
Sbjct: 496  SVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIP 555

Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRF--KTTYDFGYVALDILYAYAEDTGTYMCKATNAV 2058
            +     P   VEWY     ++ G RF    + +    +L I  A  ED+G Y C A+N  
Sbjct: 556  IQGYPRPI--VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDA 613

Query: 2059 GEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSL 2118
            G+  TT+ + +D               +K+ + E  +  KPIE                 
Sbjct: 614  GK--TTALLNLDVN-------------EKVVQPEFDKEVKPIE----------------- 641

Query: 2119 ENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAED 2178
              +K G+ A     ++    P +T  W+ +   +      +         L+I+    +D
Sbjct: 642  --VKHGEEATTSLEIKGKPKPKVT--WYKDLVPLLETRSIQLKSVGDEHTLEIINATPDD 697

Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPK 2238
             G Y C+ATNK G A  +  +KV                   +  E QG +  I  E   
Sbjct: 698  EGKYKCEATNKAGTAFRSFDIKV-------------------KVAEPQGETPTITTE--- 735

Query: 2239 ISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFG 2298
                  +T+++      +G+     C V    +PN  +E++ +GK L++  R   +F+  
Sbjct: 736  ------MTDIQ----AIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEER 783

Query: 2299 YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELES 2358
             ++L  +    ED G Y     N  G  +SA      A+  +   S +PE +  +R+ + 
Sbjct: 784  MIALSFRPIKLEDMGRYKCVISNVFGSVSSA------AEVKVEDRSLKPEVITSMRDCDC 837

Query: 2359 AE 2360
             E
Sbjct: 838  VE 839



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 113/496 (22%), Positives = 189/496 (38%), Gaps = 90/496 (18%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            KPV ++ +S    VSEG    +E ++   G P   VEW+H    V  G RF+   +  + 
Sbjct: 1998 KPV-IKEVSKTFEVSEGGTASIEVKVS--GVPVPTVEWYHGSNRVLDGDRFQVTQEGDYH 2054

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAA 1295
             L I          Y   A N+ G        R   R+D+V  T+ E A E     ED  
Sbjct: 2055 TLSIRDVGDQAAASYKCVAFNNAG--------RTTYRADLVI-TEREYAPE----FEDFD 2101

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
             +   VRE    +                 TN+ +  R  P       VEW+     + +
Sbjct: 2102 EKRIAVREGQNAI-----------------TNMTIRARPSP------DVEWYKGDTLLMS 2138

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              +           L++     +D+G Y C+ATN +G    S + R+I   + + E+  P
Sbjct: 2139 DRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIG----STSRRIIVDVEALKEA--P 2192

Query: 1416 SGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSN 1475
              + K                     ++P FVT         EG +V + CK+  +    
Sbjct: 2193 VFVSK---------------------LRPLFVT---------EGDNVSWMCKVAGMPRPT 2222

Query: 1476 LKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
              VEW+++ QP+    R++   D    +L + +   +D G+Y C   N  G+   S  L 
Sbjct: 2223 --VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQ 2280

Query: 1536 CRSTTDIVRSTQNEAGLEQIQVLEDR-----SKYHRTDMV-----DEVTTQAPICTTSLK 1585
                 +  +  +    ++ ++  E R     S   R ++       +V  +       LK
Sbjct: 2281 VDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELK 2340

Query: 1586 N-VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLP 1644
              V ++E    +F+ R+      T  + WY + + ++   RF   +          S   
Sbjct: 2341 EPVVVQESDAINFKVRVRGKPVPT--IVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASA 2398

Query: 1645 EDSGTYTCRAINALGE 1660
            ED+GTYTC A N LG+
Sbjct: 2399 EDAGTYTCEASNKLGK 2414



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 78/331 (23%), Positives = 129/331 (38%), Gaps = 36/331 (10%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            PE      DI D  EG     E  +I  G     +EWF +   +  + R           
Sbjct: 4849 PEVAEKMTDI-DAVEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTST 4905

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHI-QNIEGLKDGQS 3166
            L I    T D+G Y    TN+ G     + L   ++  G  P F     + ++ ++    
Sbjct: 4906 LVIRNCTTNDTGPYKVIGTNECGIGGAVLNLIIHEREFG--PEFIDEEGEYVKVVRSEGV 4963

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A+   TV    +P  ++ WY +G  +  +TR+ T S      L+I    + D+G Y+C A
Sbjct: 4964 ANITFTVR--GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEA 5021

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
             +K G+ F    ++      V  E +    + K      ++ AQ +              
Sbjct: 5022 RSKLGKCFRSCILDVQA---VPKEEVDHGQIVKPVITRKIRDAQGE-------------- 5064

Query: 3287 QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILY 3346
                     EG +  FE  +     P   VEW+    KL HG +Y+     G   L I  
Sbjct: 5065 ---------EGSNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITG 5113

Query: 3347 CYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
              ++++G Y+ VATN+ G  +++A +    K
Sbjct: 5114 VQKDDTGSYKVVATNQAGSSTSRAEVVVKDK 5144



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 14/236 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F+  L+ +   EG  + +  ++  +  PT  +EW ++ Q + A +R+   F     SL
Sbjct: 2192 PVFVSKLRPLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSL 2249

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE----- 751
             +   + +D G Y C   ++ G A + A L V  +A   +  +    +Q ++  E     
Sbjct: 2250 FLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDV 2309

Query: 752  DYSKYQHQESIEEQTS---QRPQFI--RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
             +S     E    + S   +  +F     L++   +QE    +F+ ++     PT  + W
Sbjct: 2310 RFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPT--IVW 2367

Query: 807  YKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            YKDG  +    R          +       AEDAG+YT  A NKLG+     ++ V
Sbjct: 2368 YKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHV 2423



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 101/425 (23%), Positives = 162/425 (38%), Gaps = 83/425 (19%)

Query: 1019 KIQYLEDASRYSKRTEEEV-KITQKPRFLGPLKGTNKIVEGQSAHFEARVE--PQSDLTM 1075
            K+    DA   S   + +V +   KP  L  +K   K VEG  A F  ++   P  D   
Sbjct: 1386 KVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDV-KGVEGDEATFNVKLSGYPSPD--- 1441

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             +EWY+   +I    R +   D    +L I  +  +D G Y  +A N AG+    A + V
Sbjct: 1442 -IEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEV 1500

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
            + R   D + I           EE +F+EP+    EI   +PV V             + 
Sbjct: 1501 KER---DYAPI----------FEEKQFLEPL----EIQVRQPVEV-------------SY 1530

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
            H+       G P   V W+ NG+ +  G   +      +  L I+ +   D G Y   A 
Sbjct: 1531 HVR------GRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLAR 1584

Query: 1256 NHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSR 1315
            N +GSA      R+            E  +E ++  E+A + T Q+R             
Sbjct: 1585 NDVGSAE-----RLF-----------EVQVEGVKPKEEAPKLTSQLR------------- 1615

Query: 1316 ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSV 1375
               +    E  +  L C ++   D +   EW  + KP+K       +++     L+   V
Sbjct: 1616 ---SARITESDDFELACDVKGTPDPS--YEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRV 1670

Query: 1376 YPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL--ILES-QHPSGLE--KIQYLEDTSRY 1430
               D G YT    N  G   +S  L ++  K    ILE+ +   G+E  K ++      Y
Sbjct: 1671 QLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSKPEILETMKDAEGIETGKAKFDVKIKAY 1730

Query: 1431 KKTDI 1435
             K ++
Sbjct: 1731 PKAEV 1735



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 3/98 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            + P  TT +    + ++G+   L   V    +PN ++EWFK+G  L    RL  +F+  +
Sbjct: 728  ETPTITTEMTDI-QAIDGEDCKLICHVTG--EPNPEVEWFKDGKPLKANHRLVPSFEERM 784

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            + LS   ++ +D G Y C  +N+ G   S A +K+EDR
Sbjct: 785  IALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 66/293 (22%), Positives = 122/293 (41%), Gaps = 16/293 (5%)

Query: 1541 DIVRSTQNEAGLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFER 1599
            +I ++T ++AG    +         R  +VD E   +AP+  + L+ + + EG    +  
Sbjct: 2154 EIRKATLDDAGTYICKATNSIGSTSRRIIVDVEALKEAPVFVSKLRPLFVTEGDNVSWMC 2213

Query: 1600 RLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            ++  +   T  VEWY +N+PL++ +R+    +    +L +     +D G Y C   N+ G
Sbjct: 2214 KVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAG 2271

Query: 1660 EAVTSGIAIVHSK--KSIYLESQH-----EGALPRLN-QLEDTSKYQRHSAQDEVITQAP 1711
             A +S    V  K  K   +E  +     EG   R + +     + +    ++ +  +  
Sbjct: 2272 SAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNE 2331

Query: 1712 VF--TMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
             F     +K+ + V E+ A +F+ R+   G P   + W ++G  +    R          
Sbjct: 2332 KFYGDDELKEPVVVQESDAINFKVRV--RGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIY 2389

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKI 1821
                   + ED+GTYTC A N+LG+      L V            +S LQ +
Sbjct: 2390 TFATYSASAEDAGTYTCEASNKLGKCSRDFNLHVDVPKEQWEAPSFKSQLQPV 2442



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 5/134 (3%)

Query: 1675 IYLESQHEG--ALPRLNQLEDTS-KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFE 1731
            ++ +S+H G  +    ++L +TS K+       E   +AP F   +      E     F 
Sbjct: 5210 LFTKSEHAGTYSCEATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLLPQNAREGDVVKFS 5269

Query: 1732 ARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINEL 1791
             ++   G P+  +EW R+GV +E+  R+TT +D  +  L++   N  DSG Y C   N  
Sbjct: 5270 CKV--TGYPEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNS 5327

Query: 1792 GEAVTSSTLFVQSK 1805
            G A +S+ L V  K
Sbjct: 5328 GWASSSAELVVGGK 5341



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 9/189 (4%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR-TVYAFGMV 3106
            PE     K I +  EG  A ++  L+ TG     ++W+     I   +R   T+ + GM 
Sbjct: 5640 PEINEKLKKI-EAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMA 5696

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTH-IQNIEGLKDGQ 3165
             L I   +  D G Y C A N++G+    V L   +K  G  P F    +   +  + G+
Sbjct: 5697 SLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEKHYG--PEFAEEELDWSKTARKGE 5754

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +A    TV     PD  + WY +G  +  +T +   S      L I    + D+G YVC 
Sbjct: 5755 NARITFTVSGNPRPD--VVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCE 5812

Query: 3226 AYNKYGEDF 3234
            A ++ G+ F
Sbjct: 5813 AQSRLGKSF 5821



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 51/192 (26%), Positives = 82/192 (42%), Gaps = 8/192 (4%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P FTT  K I D++EG+   +   +    + S  + W+ N   I    R RT +      
Sbjct: 1903 PSFTTTLKPI-DVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETYK 1959

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L +   K  D+G Y C A+N  G+A  + ++  V+K +  KP      +  E + +G +A
Sbjct: 1960 LILQDIKIKDAGQYECIASNPIGKAFCTAEMT-VNKRE-VKPVIKEVSKTFE-VSEGGTA 2016

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
              E  V  V  P   +EWYH    +    R +   +  +  L I    +  +  Y C A+
Sbjct: 2017 SIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAASYKCVAF 2074

Query: 3228 NKYGEDFTRATI 3239
            N  G    RA +
Sbjct: 2075 NNAGRTTYRADL 2086



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 18/239 (7%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            ++VE  K +P  FV++LR    V EG    + C+V  +  P   +E+Y + + L++  R+
Sbjct: 2183 VDVEALKEAPV-FVSKLR-PLFVTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRW 2238

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
             + FD    SL +     +D G Y+    N+ G   S+  + V  K +     ++   ++
Sbjct: 2239 KMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQ 2298

Query: 2352 KIRELESAEPFKRPEIPEP-VTRQR---PVFTQPLQNIDN------IQEGQTAHFDCRLI 2401
             +   E+    +   +P P VT  R    V  +     D       +QE    +F  R+ 
Sbjct: 2299 TVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRV- 2357

Query: 2402 PVGDPTLKVEWFRNEKLIEDSSRI-TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
              G P   + W+++ +++ D  R   ++    Y   T S    ED G Y C ASN LG+
Sbjct: 2358 -RGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYS-ASAEDAGTYTCEASNKLGK 2414



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 59/218 (27%), Positives = 98/218 (44%), Gaps = 18/218 (8%)

Query: 3707 VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAG 3766
            V EG  V + C+V  +  PT  ++W+ + +P    +R     D    +L +     +D G
Sbjct: 2203 VTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKG 2260

Query: 3767 EYTCRATNKWGSATTTAKITC--SAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEE- 3823
             Y C  TN  GSA ++A++     A +  V+E ++    + E  +     R S  P+ E 
Sbjct: 2261 VYNCVITNSAGSAFSSAELQVDKKANKPKVIE-KMNDVQTVEGTEARFDVRFSGLPRPEV 2319

Query: 3824 -----PIVSTPPKFI--TQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875
                  I     KF    ++K    V+ES+ + F+ RV  K  P   I WY++G+++   
Sbjct: 2320 TWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVP--TIVWYKDGEMVRDV 2377

Query: 3876 HRYRTVYDMGFVSLDILY-VYAEDSGEYICRAVNDFGE 3912
             R+  +   G +     Y   AED+G Y C A N  G+
Sbjct: 2378 RRFE-IRSRGDIYTFATYSASAEDAGTYTCEASNKLGK 2414



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 69/256 (26%), Positives = 101/256 (39%), Gaps = 42/256 (16%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            +T G+ ++L  T+     P   V WY +G  +      +         L IL+  +E  G
Sbjct: 5161 ITRGNQLNLNVTIR--GKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAG 5218

Query: 2049 TYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQR 2108
            TY C+AT+ +G     +S K D +               IQ  E    PK          
Sbjct: 5219 TYSCEATSKLGN----TSAKFDVQ---------------IQAPEA--APKA--------- 5248

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P FL  L   +N +EGD   F C+V    +P   I+W  +G  + +  R  T +D  +  
Sbjct: 5249 PAFLKQLLP-QNAREGDVVKFSCKVTGYPEPE--IEWTRDGVSMESDERVTTWYDGEHST 5305

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQ-G 2227
            L I      DSG Y C   N  G A ++  L V G       TQ P   + +++L A  G
Sbjct: 5306 LSIHNANHADSGMYKCTLKNNSGWASSSAELVVGG------KTQRPRLSDNMKELFATVG 5359

Query: 2228 HSTRIEVEEPKISPPR 2243
               R EV       P+
Sbjct: 5360 GEARFEVTMKATPKPK 5375



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            + P  +  + +I+ ++G +  L C +   G+    VEWF +GKP+K  HR  P++E   +
Sbjct: 728  ETPTITTEMTDIQAIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMI 785

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            AL    +  ED G Y C  +N  G   ++  ++V
Sbjct: 786  ALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKV 819



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 46/207 (22%), Positives = 84/207 (40%), Gaps = 12/207 (5%)

Query: 383  IEISEKALAPQFVKV--CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            + + E+   P+F++     ++    G        + G P P V W+  D  +  D     
Sbjct: 3372 LTVKERLFGPEFLEEEGVWNKVAKAGGFVNISFTLKGNPRPHVVWY-RDGILLYDTTRMD 3430

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV-------IEKEQVVAPKF 493
            + +    H + I  +TL D+G   C AR++ G     C L +        E++++     
Sbjct: 3431 IRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRSCTLEIKVPSMGGPEEKKISKALI 3490

Query: 494  VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI--HTDGGASTLDIP 551
             +  + +   EG  V    R  G P P + W +  + +  + + +I    + G  +L + 
Sbjct: 3491 GQGDNDVQAVEGWKVQFQTRITGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVN 3550

Query: 552  RAKASDAAWYQCTAQNVAGSTATRARL 578
                 D   Y+C A N AGS+A R  L
Sbjct: 3551 DVTKDDIGTYKCLATNSAGSSACRINL 3577



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 52/198 (26%), Positives = 86/198 (43%), Gaps = 12/198 (6%)

Query: 3045 GRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFG 3104
            G  P F +  + I +I+EG    ++ S   TG     ++WF +   I+ S R +  Y   
Sbjct: 1018 GDTPTFMSKLEPI-EITEGD--DFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGN 1074

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            +  L +   +  D G Y C  TN +G   +S K +     K  +P     + ++  ++ G
Sbjct: 1075 VSALTVKEAELDDDGVYKCVVTNNFG--SVSSKADVTVLKKHLRPEVLQKMDDVRTVEGG 1132

Query: 3165 QSAHFECTVVPVDD-PDMKIEWYHNGQPMRHSTR--IKTVSDFGFVVLDIAYTQNHDSGE 3221
            + A+F    V +D  P  +IEWY     +    R  IKT  +    +L I   +  D+G 
Sbjct: 1133 K-ANF---AVKIDAFPKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGT 1188

Query: 3222 YVCRAYNKYGEDFTRATI 3239
              C A N  G+   RA +
Sbjct: 1189 VKCSATNAAGKTVVRADL 1206



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 68/263 (25%), Positives = 104/263 (39%), Gaps = 40/263 (15%)

Query: 1701 SAQDEVITQA--PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR 1758
            SA+ +VI +   P     MKD++  E   A F  +L   G P   +EW      I    R
Sbjct: 1399 SAKLKVIRKCTKPEVLEKMKDVKGVEGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGR 1456

Query: 1759 LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESAL 1818
                 D    +L +K +N +D GTY C A NE G+        V  +A L+++ +  + +
Sbjct: 1457 YKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGK--------VTQRAELEVKERDYAPI 1508

Query: 1819 QKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRV 1878
             + +Q  +    Q R+ VEV+                        Y  R  P P     V
Sbjct: 1509 FEEKQFLEPLEIQVRQPVEVS------------------------YHVRGRPKP----TV 1540

Query: 1879 EWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
             W+ NGK L+ G      +   +  L IL    ED+G Y C A N++G A     + V+ 
Sbjct: 1541 TWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVEG 1600

Query: 1939 KESIIRDSQHESALEKIQYLEDD 1961
             +      +  S L   +  E D
Sbjct: 1601 VKPKEEAPKLTSQLRSARITESD 1623



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 6/174 (3%)

Query: 3069 EASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            E S    G     + W+ NGK +     +          L IL ++  D+G+Y C A N 
Sbjct: 1527 EVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARND 1586

Query: 3129 WGQAE--ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWY 3186
             G AE    V++E V K K + P+ T+ +++    +  +S  FE        PD   EW 
Sbjct: 1587 VGSAERLFEVQVEGV-KPKEEAPKLTSQLRS---ARITESDDFELACDVKGTPDPSYEWL 1642

Query: 3187 HNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
             + +P++    + +  D     L+    Q  D G Y     N +G  ++ A ++
Sbjct: 1643 KDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLD 1696



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 57/203 (28%), Positives = 87/203 (42%), Gaps = 39/203 (19%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFG-FIALDIDYIYARDAGEYTCRATNKWGSATT 3781
            G P+  + W+ + R    G R H L   G      +  + A DAG Y C A N+ G    
Sbjct: 1829 GKPSPDVSWYRDDRLLLDG-RKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVG---- 1883

Query: 3782 TAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841
                  SA R+  +E ++P+                   ++E      P F T +K   V
Sbjct: 1884 ------SATRNFNVEIEVPKA------------------RDEA-----PSFTTTLKPIDV 1914

Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRN-GKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
             E E   F CRV  + +P   + WYRN  +++P G R RT +D     L +  +  +D+G
Sbjct: 1915 TEGENHTFICRVHARPEPS--VTWYRNKNEIVPDG-RSRTTFDGETYKLILQDIKIKDAG 1971

Query: 3901 EYICRAVNDFGEDFTKATISCKK 3923
            +Y C A N  G+ F  A ++  K
Sbjct: 1972 QYECIASNPIGKAFCTAEMTVNK 1994



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 41/115 (35%), Positives = 56/115 (48%), Gaps = 5/115 (4%)

Query: 3676 EETLHKREEITIED--EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH 3733
            +ET  +  +I IED  +    P F   ++ ++DV E     F C V   G P  RI WF 
Sbjct: 4434 KETTSQLFDIHIEDVCKSALAPGFKSALR-SLDVTEDESAEFRCEVS--GSPAPRIQWFM 4490

Query: 3734 NGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            N +P +  SR+ T +D     L I     +D G Y C A N  GSAT+TA +  S
Sbjct: 4491 NDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNVS 4545



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 44/149 (29%), Positives = 69/149 (46%), Gaps = 9/149 (6%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP FT P++ I + E     F   +   G P   VEW R+  P+   +RL T  D   V 
Sbjct: 5543 APAFTAPLQHIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829
            L ++  N  D+G + C   N+LG   +S++L V    S   + +    L+KI+  E    
Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNEGYS---KPEINEKLKKIEAFEGG-- 5655

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSE 1858
             + R D+ V     PR +    G TK+++
Sbjct: 5656 -EARFDLLVTGFPPPR-VDWYRGTTKITD 5682



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 65/254 (25%), Positives = 98/254 (38%), Gaps = 21/254 (8%)

Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY 3101
            +D    PE  T  +D  D  E + A +      +G     IEWF     I    R     
Sbjct: 820  EDRSLKPEVITSMRDC-DCVEEETASFHCEF--SGKPEPEIEWFCGPNPIVPGGRFHVTE 876

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
               +  L I   K  D+G Y C A+N  G+     +L+  +K     P F      I+ L
Sbjct: 877  EGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEKHFA--PEFEDWKDTIDAL 934

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS--TRIKTVSDFGFVVLDIAYTQNHDS 3219
             DGQ  +    V     P  +I W  +G+ +R++   +IK   D   +VL        D+
Sbjct: 935  -DGQDVNISTWV--RGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVL--YKVSPEDA 989

Query: 3220 GEYVCRAYNKYG---EDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPST 3276
            G Y CRA N  G   +D T  T+    K G       P  ++K+  +E  +G   Q    
Sbjct: 990  GMYTCRAKNNAGIVSKDVT-ITVEALQKKGD-----TPTFMSKLEPIEITEGDDFQLSCN 1043

Query: 3277 PSAEPPKFITQIQD 3290
             +  P   +   +D
Sbjct: 1044 VTGRPQPEVQWFRD 1057



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 42/183 (22%), Positives = 75/183 (40%), Gaps = 7/183 (3%)

Query: 391  APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
            AP F    Q   + EG        V G+P P + W  +D  +   + H++     G    
Sbjct: 2432 APSFKSQLQPVILEEGGTGVLVGEVAGKPLPTIQWMKDDYPVL--FGHRVRPQFDGRTCK 2489

Query: 451  MI-TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            +I     + D G+  C+ +N+ GE + +  + V      V P+ +E+ + L + EG    
Sbjct: 2490 VIFREALIGDGGMYECIIKNQCGEASSKALVGV--NRGTVGPEIIEKPAGLVIVEGNDSR 2547

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG--GASTLDIPRAKASDAAWYQCTAQN 567
             + R  G PTP + W      +    + RI ++   G  +L + + +      Y+  A N
Sbjct: 2548 FDVRIRGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTGHYRIVASN 2607

Query: 568  VAG 570
              G
Sbjct: 2608 EHG 2610



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 59/230 (25%), Positives = 92/230 (40%), Gaps = 37/230 (16%)

Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            R E+ ++D+   P    +     I +  G  ++ +  +   G P   + W+ +G    T 
Sbjct: 5136 RAEVVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIR--GKPKPSVVWYKDGNKILTS 5193

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801
              V   +      L I +  +  AG Y+C AT+K G+         SAK D+ +  Q P+
Sbjct: 5194 RNVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNT--------SAKFDVQI--QAPE 5243

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861
                             APK        P F+ Q+      E + V+F C+V    +P+ 
Sbjct: 5244 A----------------APKA-------PAFLKQLLPQNAREGDVVKFSCKVTGYPEPE- 5279

Query: 3862 RIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
             IEW R+G  + S  R  T YD    +L I      DSG Y C   N+ G
Sbjct: 5280 -IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSG 5328



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 122/559 (21%), Positives = 204/559 (36%), Gaps = 67/559 (11%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            PEF     + I  +   A    RL    +    V W+ +G  L    ++K         L
Sbjct: 379  PEFADGDLEPIEVKEDQA-VNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHEL 437

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV--KGRQGIILEPQLPSHFKSGTESIQKL 3675
             I      D G Y C+A+N  G    + K+ V  KG   +I    +P   +  T +   +
Sbjct: 438  SIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSV 497

Query: 3676 EETLHKREEITIE----------------DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRV 3719
              TL    E  ++                 +    P F  +++D +   E   V F+  +
Sbjct: 498  NTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVED-VTALETEQVWFEIPI 556

Query: 3720 EPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG 3777
            +  G P   ++W+        G R  +    +    +L ID     D+G Y C A+N  G
Sbjct: 557  Q--GYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAG 614

Query: 3778 SATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG----RISDAPKEE--------PI 3825
               TTA +        V++ +  + +   ++K  E       I   PK +        P+
Sbjct: 615  K--TTALLNLDVNEK-VVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDLVPL 671

Query: 3826 VSTPPKFITQI-KSHTVE------ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878
            + T    +  +   HT+E      + EG +++C    K     R    +     P G   
Sbjct: 672  LETRSIQLKSVGDEHTLEIINATPDDEG-KYKCEATNKAGTAFRSFDIKVKVAEPQGETP 730

Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938
                +M     DI  +  ED  + IC      GE   +        P       VP   +
Sbjct: 731  TITTEM----TDIQAIDGEDC-KLICHVT---GEPNPEVEWFKDGKPLKANHRLVPSFEE 782

Query: 3939 RSEALT----QME--ATIKKYTSEVYLTEDDLYDV---DKKQPPRFVTQIQSQTSLVEME 3989
            R  AL+    ++E     K   S V+ +     +V   D+   P  +T ++     VE E
Sbjct: 783  RMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRSLKPEVITSMRD-CDCVEEE 841

Query: 3990 TTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCR 4049
            T  F C+ +  G P  ++EWF    P++   RF    +    ++    +  ED+G Y C 
Sbjct: 842  TASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCV 899

Query: 4050 ATNLYGMDETKAVIKTTGK 4068
            A+N  G   T+A +K   K
Sbjct: 900  ASNAAGKTTTRAELKVNEK 918



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 66/269 (24%), Positives = 112/269 (41%), Gaps = 46/269 (17%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            + P F   ++  E+TEG    L   +T    P   V+W+ +   ++   RFK +YD    
Sbjct: 1019 DTPTFMSKLEPIEITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFKASYDGNVS 1076

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
            AL +  A  +D G Y C  TN  G   + + V V                     L+K+ 
Sbjct: 1077 ALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV---------------------LKKHL 1115

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
            RP+ +++            +  +  ++ G +A+F  +++    P   I+W+    KI  G
Sbjct: 1116 RPEVLQK------------MDDVRTVEGG-KANFAVKIDAFPKPE--IEWYLGATKITDG 1160

Query: 2156 HRYRTTHD---FGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQ 2212
             R++   D     Y+ L I     +D+GT  C ATN  G+ V    L+V   +N+     
Sbjct: 1161 GRFKIKTDKENCSYI-LFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVE-EKNVAPSFH 1218

Query: 2213 HPNGLEKIRQLEAQGHSTRIEVE-EPKIS 2240
               G  ++R  E +  S   E+  +PK S
Sbjct: 1219 GRQG--RLRVKEGREASVYFEISGKPKPS 1245



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 95/369 (25%), Positives = 148/369 (40%), Gaps = 46/369 (12%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G+    V W KDG  +  ++R+ T        L I S+T  DAG Y C A + +G+   S
Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031

Query: 997  ANLTI--VTKKDII-AESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPR---FLGPLK 1050
              L +  V K+++   +   P    KI+  +     + R E  VK    P    + G +K
Sbjct: 5032 CILDVQAVPKEEVDHGQIVKPVITRKIRDAQGEEGSNIRFEIHVKSHPPPHVEWYRGSIK 5091

Query: 1051 GTN----KIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIA 1106
              +    +I EG  A+       Q D T + +     +  +S +R +       +A  +A
Sbjct: 5092 LAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDKPLAPKVA 5151

Query: 1107 SVRAEDSGVYTVVARNAA-------GEAQLSA-----------SMTVETRSSID------ 1142
             + A  +G  T+   N         G+ + S            S  V+ RS  D      
Sbjct: 5152 EMTA--TGPITITRGNQLNLNVTIRGKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLII 5209

Query: 1143 --TSSIHRGLY--EKTRHI--EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196
              T S H G Y  E T  +    +KF +   Q  E +   P F++ L  P    EG  + 
Sbjct: 5210 LFTKSEHAGTYSCEATSKLGNTSAKF-DVQIQAPEAAPKAPAFLKQLL-PQNAREGDVVK 5267

Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256
              C++   G P   +EW  +G S+    R  T+YD     L I +A  AD+G Y     N
Sbjct: 5268 FSCKVT--GYPEPEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKN 5325

Query: 1257 HLGSAHTSA 1265
            + G A +SA
Sbjct: 5326 NSGWASSSA 5334



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 3/114 (2%)

Query: 2624 AAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGV 2683
            A  N   E+ V     +AP FTT LK  D + EG++     +V  R +P+  + W++N  
Sbjct: 1885 ATRNFNVEIEVPKARDEAPSFTTTLKPID-VTEGENHTFICRVHARPEPS--VTWYRNKN 1941

Query: 2684 TLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             +    R ++TFD     L +  ++  D+G Y C A+N +G+A  TA + +  R
Sbjct: 1942 EIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 3/98 (3%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN 963
            E    P F T +   +S+ EG +  F A +   G     ++W KD  P+ ++ RI TFF+
Sbjct: 3977 EKWSSPIFVTELSP-LSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFD 4033

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
               V L I  +T+ D G Y     N  G AT+SA L++
Sbjct: 4034 GHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 54/204 (26%), Positives = 89/204 (43%), Gaps = 31/204 (15%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G+P   + W+ +G   +  +R+ T +      L+I  + + DAG Y C A +K G     
Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCF-- 5029

Query: 3783 AKITCSAKRDIVLESQ-LPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841
                    R  +L+ Q +P+       +E++ G+I      +P+++       +I+    
Sbjct: 5030 --------RSCILDVQAVPK-------EEVDHGQIV-----KPVITR------KIRDAQG 5063

Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGE 3901
            EE   +RFE  V  K  P   +EWYR    L  G +Y+     G  SL I  V  +D+G 
Sbjct: 5064 EEGSNIRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGS 5121

Query: 3902 YICRAVNDFGEDFTKATISCKKLP 3925
            Y   A N  G   ++A +  K  P
Sbjct: 5122 YKVVATNQAGSSTSRAEVVVKDKP 5145



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 37/113 (32%), Positives = 52/113 (46%), Gaps = 3/113 (2%)

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
            S+++  +     A  +AP F+ QL  P    EG    + C++  YP+P   +EW  +G  
Sbjct: 5232 SAKFDVQIQAPEAAPKAPAFLKQLL-PQNAREGDVVKFSCKVTGYPEPE--IEWTRDGVS 5288

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            ++S  R  T  D   + L I      DSG Y C   NN G A SS  L V  K
Sbjct: 5289 MESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK 5341



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 48/160 (30%), Positives = 67/160 (41%), Gaps = 14/160 (8%)

Query: 3399 TLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYW 3458
            T     V      V  E+  AP FT PL +I+ L EG+   F   +T    P   VEWY 
Sbjct: 5523 TAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDIL-EGDTTRFIGEITGVPVP--VVEWYR 5579

Query: 3459 NGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
            + + +    R RT+ D   VIL +  T   D+G + C   N+ G   ++AS+ V      
Sbjct: 5580 DDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVN----- 5634

Query: 3519 ILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPP 3558
              E      +   + KI A EG     D L     +G PP
Sbjct: 5635 --EGYSKPEINEKLKKIEAFEGGEARFDLLV----TGFPP 5668



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 3/95 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP  T+ LK  DK+ EG+       V  +  P   I W+K+G  +    R+K +FD   
Sbjct: 183  KAPTVTSELKP-DKVQEGEQYKFTCAVTGKPKP--VISWYKDGQPIKADRRVKDSFDGTT 239

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             TL I  ++ DD G Y  + TN LG   STA +++
Sbjct: 240  STLLIKDVKQDDKGTYKVEITNDLGSISSTADLEV 274



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 3/104 (2%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            V E +G+ P  T  +++I+ + +GE+      +T   +PN +VEW+ +GK LKA  R   
Sbjct: 722  VAEPQGETPTITTEMTDIQAI-DGEDCKLICHVT--GEPNPEVEWFKDGKPLKANHRLVP 778

Query: 3472 FCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
              +   + L   P   ED G Y C   N +G   + A +KV+ +
Sbjct: 779  SFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F S L ++   E ++  F C V  S  P  +I+WF N++P+   +R  ++ D     L I
Sbjct: 4457 FKSALRSLDVTEDESAEFRCEVSGS--PAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAI 4514

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            T    +D+G+Y C A N  GSAT++  L
Sbjct: 4515 TKATLQDTGVYKCLAVNDNGSATSTADL 4542



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 85/401 (21%), Positives = 156/401 (38%), Gaps = 37/401 (9%)

Query: 1813 QHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
            Q +    K++   D        D+EV    A   + +     +  EG  A +E + + YP
Sbjct: 249  QDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFKGYP 308

Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSND--FGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
             P  + EW+ + K ++   R++ + D     ++L I  +  +DSG Y C A N  G+   
Sbjct: 309  IP--KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGEC-- 364

Query: 1931 SIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVT 1990
            ++R +++ K         +  LE I+  ED +   R     +    KP+        ++ 
Sbjct: 365  NLRADLKVKNKPFAPEFADGDLEPIEVKEDQAVNVRLTVTGN---PKPEVTWYKDGTQLH 421

Query: 1991 EGHPVHLEAT------LTPVNDPTMRVEWYCN-GRPVQQGHR-FKTTYDFGYVALDILYA 2042
            +   + L+AT        P        +++C    P+    R FK T     VA  I   
Sbjct: 422  DTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVI--- 478

Query: 2043 YAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEE 2102
               ++G    +     G   + ++   DA          E ++K   E+        I  
Sbjct: 479  ---ESGLMPLQVRKETGAKWSVNTTLDDA---------GEYKVKVTNEVGSVTSLADINV 526

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY--RT 2160
            ++   +P FL  +  +  L E ++  FE  ++    P   ++W+    +I+ G R+    
Sbjct: 527  QKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQ--GYPRPIVEWYRGTTRIKDGGRFTISE 583

Query: 2161 THDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            + +    +L I     EDSG Y C A+N  G+      L V
Sbjct: 584  SEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDV 624



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 50/184 (27%), Positives = 74/184 (40%), Gaps = 6/184 (3%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            PE     KD+  + EG  A +   L  +G  S  IEW+Y    I    R +         
Sbjct: 1411 PEVLEKMKDVKGV-EGDEATFNVKL--SGYPSPDIEWYYGTTRIRDGGRYKFSRDDQKYS 1467

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I      D GTY C A+N+ G+     +LE   K +   P F    Q +E L+     
Sbjct: 1468 LTIKDLNLQDIGTYKCIASNEAGKVTQRAELEV--KERDYAPIFEEK-QFLEPLEIQVRQ 1524

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
              E +      P   + W+ NG+ +R    ++  S   +  L I  ++  D+G Y C A 
Sbjct: 1525 PVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLAR 1584

Query: 3228 NKYG 3231
            N  G
Sbjct: 1585 NDVG 1588



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 53/207 (25%), Positives = 91/207 (43%), Gaps = 32/207 (15%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXX 2594
            +G+P     W+ +GV+L   SR           L+I  +  +DAG Y+C+A +R G    
Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236

Query: 2595 XXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKL 2654
                          +A+RP    ++Q  +   +K+  +                      
Sbjct: 4237 SCTLDV--------KAVRPRRGNEVQACKPQTSKMANVTA-------------------- 4268

Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTF--DFGLVTLSINSLRNDDS 2712
            VEG  V L+ ++     P   +EWF+    +T G R K+    D GL +L I+ ++ +DS
Sbjct: 4269 VEGWKVQLDTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDS 4326

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHW 2739
            G Y   A+N LGEA + A + ++ +H+
Sbjct: 4327 GSYRAVASNNLGEATTLAELTVKGKHF 4353



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 76/291 (26%), Positives = 123/291 (42%), Gaps = 31/291 (10%)

Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            R ++ +++ KP  P F     + I+V E   V+   R+   G+P   + W+ +G      
Sbjct: 367  RADLKVKN-KPFAPEFADGDLEPIEVKEDQAVNV--RLTVTGNPKPEVTWYKDGTQLHDT 423

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI-VLESQL- 3799
             ++          L I      D G+Y C A+N  GS   T K+T   K    V+ES L 
Sbjct: 424  KKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLM 483

Query: 3800 PQGM----------------SGE-KIKEL-ERGRISD-APKEEPIVSTPPKFITQIKSHT 3840
            P  +                +GE K+K   E G ++  A          P+F+ +++  T
Sbjct: 484  PLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVT 543

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY--RTVYDMGFVSLDILYVYAED 3898
              E+E V FE  ++    P+  +EWYR    +  G R+      +    SL I     ED
Sbjct: 544  ALETEQVWFEIPIQGY--PRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTED 601

Query: 3899 SGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949
            SG Y C A ND G+  T A ++   + + ++Q +  + +K  E     EAT
Sbjct: 602  SGPYKCVASNDAGK--TTALLNL-DVNEKVVQPEFDKEVKPIEVKHGEEAT 649



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 54/229 (23%), Positives = 97/229 (42%), Gaps = 10/229 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F+++++   V E + V + C+V     P+  +EWYR+ + L +  R++  +D    SL
Sbjct: 2192 PVFVSKLRPLFVTEGDNVSWMCKVAGM--PRPTVEWYRDNQPLRADTRWKMDFDGRVCSL 2249

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949
             +     +D G Y C   N  G  F+ A +   K  +   + +V   M   + +   EA 
Sbjct: 2250 FLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKAN---KPKVIEKMNDVQTVEGTEAR 2306

Query: 3950 IKKYTSEVYLTEDDLY-DVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
                 S +   E   Y +  K +  +F    + +  +V  E+     ++   G P   + 
Sbjct: 2307 FDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIV 2366

Query: 4009 WFFNGKPLLHKNRFTPIYDFG--YVAMNFGWVYPEDSGEYLCRATNLYG 4055
            W+ +G+ +    RF  I   G  Y    +     ED+G Y C A+N  G
Sbjct: 2367 WYKDGEMVRDVRRF-EIRSRGDIYTFATYS-ASAEDAGTYTCEASNKLG 2413



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 33/106 (31%), Positives = 56/106 (52%), Gaps = 3/106 (2%)

Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
            +V  A ++AP F T L  P  ++EG++  + CR+   P+P+  V WY N   +    R R
Sbjct: 1894 EVPKARDEAPSFTTTLK-PIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSR 1950

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
            T+ D     L +  +  +D+G+Y C A N +G+A  +  + V  +E
Sbjct: 1951 TTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKRE 1996



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 43/198 (21%), Positives = 78/198 (39%), Gaps = 8/198 (4%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            ++SEG  A  E  +  +G     +EW++    +    R +         L I       +
Sbjct: 2009 EVSEGGTASIEVKV--SGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAA 2066

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
             +Y C A N  G+   + + + V   +   P F    +    +++GQ+A    T+     
Sbjct: 2067 ASYKCVAFNNAGRT--TYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTIRARPS 2124

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR-- 3236
            PD  +EWY     +    +I   +  G   L+I      D+G Y+C+A N  G    R  
Sbjct: 2125 PD--VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRII 2182

Query: 3237 ATINCYGKGGVYLESLQP 3254
              +    +  V++  L+P
Sbjct: 2183 VDVEALKEAPVFVSKLRP 2200



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 65/250 (26%), Positives = 94/250 (37%), Gaps = 14/250 (5%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+F  +     V  +EG   +  V  +  PK  +EW+++GK L    R           L
Sbjct: 3129 PEFDEEESPKPVIVNEGEEAQMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYL 3188

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949
             I +V  ED G Y C A +  G       +S  K+P    +  +P    +   L  +E  
Sbjct: 3189 VIYHVTPEDEGSYKCVASSTNGRSSRTFDLSV-KVPKPKDKWSLPAFSSKLRPLETLEGE 3247

Query: 3950 IKKYTSEVY-----LTEDDLYDVDKKQPPRFVTQIQSQT-SLVEMETTKFECQLAPV--- 4000
              K+   V        E    D   K   RF T    +   LV  +T  FEC  A +   
Sbjct: 3248 KTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAH 3307

Query: 4001 --GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDE 4058
              G P   VEWF     L    R+          +    ++ ED+G Y   ATN +G   
Sbjct: 3308 VAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHG--S 3365

Query: 4059 TKAVIKTTGK 4068
            T +V+  T K
Sbjct: 3366 TGSVVDLTVK 3375



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 80/344 (23%), Positives = 132/344 (38%), Gaps = 41/344 (11%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC- 3140
            + WF+    I +  R        +  L I G +    GTY C ATN  G+    V   C 
Sbjct: 3814 VTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTYKCIATNDAGK----VTAHCH 3869

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            +D +K          +  E +   +             P   +EW+ +GQ + ++  +  
Sbjct: 3870 LDVTKQDFAPIVAGSEMPEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHL 3929

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260
             +   +  LD+  T   DSG Y   A N  G  +    +N        + ++ P      
Sbjct: 3930 RARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNLN--------VTAIAPKE---- 3977

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFY 3320
                     +  +P   +   P  +T+  D TK V    AH     +P       ++W+ 
Sbjct: 3978 ---------KWSSPIFVTELSPLSVTE-GDYTKFV----AHVSGVPLP------SIQWYK 4017

Query: 3321 NGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
            +   +   HR RTF D  +V L I     E+ G+Y+ V  N+ G  ++ A L    +   
Sbjct: 4018 DDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGK 4077

Query: 3381 ILDSQLPRGMEG--GLEKLQTLEDSMVRRKDTSVEEEKGKAPVF 3422
               +QL R +EG  G E   T++ S V   +  VE  +GK  +F
Sbjct: 4078 PAITQLYRDVEGFDGSESELTVQVSGVPAAE--VEWFRGKTKLF 4119



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 65/233 (27%), Positives = 95/233 (40%), Gaps = 36/233 (15%)

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
            QD + +V   +  +PI    V EG  V + A +     PT  VEW+ +G+ +   +    
Sbjct: 3875 QDFAPIVAGSEMPEPIV---VREGCEVSMMANVRGKPAPT--VEWFKDGQLLSNTNNLHL 3929

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKI 2088
                 Y  LD+L     D+GTY   ATN +G A    ++ V A                I
Sbjct: 3930 RARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTA----------------I 3973

Query: 2089 QELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHN 2148
               EK+  P            +F+T L+ L ++ EGD   F   V  +  P  +I W+ +
Sbjct: 3974 APKEKWSSP------------IFVTELSPL-SVTEGDYTKFVAHVSGV--PLPSIQWYKD 4018

Query: 2149 GQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               I + HR RT  D   V L I     ED G Y     N+ G A ++  L V
Sbjct: 4019 DNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 46/181 (25%), Positives = 73/181 (40%), Gaps = 7/181 (3%)

Query: 3059 DISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDS 3118
            D++EG        +  +G     +EW  N + +  + R +T +      L I      D+
Sbjct: 1325 DVTEGDDCRLTCKV--SGYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADA 1382

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
              Y     N  G+   S KL+ + K    KP     +++++G+ +G  A F   +     
Sbjct: 1383 VPYKVVVRNDAGEVSSSAKLKVIRKCT--KPEVLEKMKDVKGV-EGDEATFNVKLSGYPS 1439

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRAT 3238
            PD  IEWY+    +R   R K   D     L I      D G Y C A N+ G+   RA 
Sbjct: 1440 PD--IEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAE 1497

Query: 3239 I 3239
            +
Sbjct: 1498 L 1498



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 47/144 (32%), Positives = 67/144 (46%), Gaps = 10/144 (6%)

Query: 3376 SKENL-ILDSQLPRGMEGGLEKLQTL----EDSMVRRKDTS--VEEEKGKAPVFTVPLSN 3428
            S++N+  L    P   +GGL K        E SM+   D    V EE   AP F + L+ 
Sbjct: 4702 SRDNVYFLRFARPSVKDGGLYKCVATNEHGEASMLFNLDVEGHVPEEDWSAPSFVIELTP 4761

Query: 3429 IENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPE 3488
               + EGE+   E  +T T  P  KVEW+ N K +K     R++ D   + L +  T  E
Sbjct: 4762 T-TVTEGESTALEVEITGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLE 4818

Query: 3489 DSGEYLCRAYNNYGEAVTTASMKV 3512
            D+G Y C   N+ G A + A + V
Sbjct: 4819 DAGLYRCTILNDLGTASSMADLSV 4842



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 5/115 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F  P+++ ++ EG        +T V  P   VEWY + RPV + HR +T  D   V L
Sbjct: 5544 PAFTAPLQHIDILEGDTTRFIGEITGVPVPV--VEWYRDDRPVTRDHRLRTYSDGRVVIL 5601

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092
             +      D G + C   N +G   +++S+ V+   G     ++E +LKKI+  E
Sbjct: 5602 LLRQTNISDAGVFKCVLRNDLGTVASSASLNVN--EGYSKPEINE-KLKKIEAFE 5653



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 60/239 (25%), Positives = 88/239 (36%), Gaps = 12/239 (5%)

Query: 3034 KEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEA 3093
            KEP      DT  P +   V K   D            ++      + IEWF     +  
Sbjct: 2719 KEPKSVDSTDTRAPGQLIPV-KHKFDFEGVPGGKARCDVLVKKSDIIDIEWFRGTNMLRD 2777

Query: 3094 SHRIRTVYAFGMVVLEILGTKTT--DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF 3151
              + + + +     L ++       D+GTY C      GQ  I  +L    K K Q P F
Sbjct: 2778 GDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHI--KEKQQAPLF 2835

Query: 3152 TTHIQNIE--GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVL 3209
                 + E   L  GQ  +   TV     P   I WY +G+P+  + RI   S      L
Sbjct: 2836 LDEKVSQEKFSLPQGQEMNKSFTVT--GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYL 2893

Query: 3210 DIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG---KGGVYLESLQPDSLAKIRELES 3265
             I   +  D+G Y C A N+ G  +    ++      KG     SL+   +A I E +S
Sbjct: 2894 GILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPKVKGEAPSFSLELRPIAAIEEFDS 2952



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 70/354 (19%), Positives = 137/354 (38%), Gaps = 22/354 (6%)

Query: 46   RQMTTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSW 105
            R   T  E S     +        +P I E+  ++     G +AKF  ++ G P P V+W
Sbjct: 3758 RCTATNQEGSTSSSAVIVVNRASITPRIIEKP-RDVDAVDGTDAKFTVRVEGFPQPKVTW 3816

Query: 106  TRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEAICSVYI--- 161
              +   +V   +Y +    + GD+ SL+I+ +     G Y C A N  G+     ++   
Sbjct: 3817 FHESTKIVSRGRYEI---SRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVT 3873

Query: 162  -QPEGXXXXXXXXXXXXXYRHVSE-TVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTD 219
             Q                 R   E ++     G    T E  +  Q ++ TN     +  
Sbjct: 3874 KQDFAPIVAGSEMPEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARG 3933

Query: 220  DFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEI-DRSLGPVSP------PKIAQKP 272
            ++    F   LL+     +S T ++V  +D+  +  I + ++  ++P      P    + 
Sbjct: 3934 EY----FNLDLLKTTQ-ADSGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTEL 3988

Query: 273  RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
                + EG   +F   +SG P P + W+K+   + ++++       +   L +      D
Sbjct: 3989 SPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLED 4048

Query: 333  SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEIS 386
             G Y ++ +N +G   +S  L+V          Q  + +      E+E  +++S
Sbjct: 4049 QGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVEGFDGSESELTVQVS 4102



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
           ++QEG    F   +T    P   + WYKDG+PI A  R+   F+    +L I  ++ +D 
Sbjct: 195 KVQEGEQYKFTCAVTGKPKPV--ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDK 252

Query: 841 GSYTVRAVNKLGEAISTASIRVAAR 865
           G+Y V   N LG   STA + V  +
Sbjct: 253 GTYKVEITNDLGSISSTADLEVTPK 277



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 3/97 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F + L+  + + EG    L   V  R  P  +++WF++ V +    R K+++D  +  
Sbjct: 1021 PTFMSKLEPIE-ITEGDDFQLSCNVTGRPQP--EVQWFRDEVLIKPSRRFKASYDGNVSA 1077

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
            L++     DD G+Y C  TN  G   S A + +  +H
Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH 1114



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 4/103 (3%)

Query: 764  EQTSQRPQFI--RPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            ++  Q P F+  +  Q+   L +G+  +     T    PT  + WYKDG P+  + RI  
Sbjct: 2827 KEKQQAPLFLDEKVSQEKFSLPQGQEMN--KSFTVTGSPTPHITWYKDGEPLDDTRRIDI 2884

Query: 822  IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
                    L I++L+ EDAG+YT  A N++G A  +  + V A
Sbjct: 2885 RSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTA 2927



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            +AP FS  L  I  +E  +  L C +   G    +++W  NGKP+++  R R  Y+    
Sbjct: 2933 EAPSFSLELRPIAAIEEFDSKLICHVS--GKPKPQIKWTKNGKPVESDGRLRTDYDGIVA 2990

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             L +  V  +D+G Y C A+N  G   +S AL V
Sbjct: 2991 YLSIWQVSHDDAGTYECIASNAAGTVSSSAALTV 3024



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 48/192 (25%), Positives = 79/192 (41%), Gaps = 8/192 (4%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F +  + + D++E + A +   +  +G  +  I+WF N + +    RI T     +  
Sbjct: 4455 PGFKSALRSL-DVTEDESAEFRCEV--SGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I      D+G Y C A N  G A  +  L  V   +  KP F   ++ +  +  G+ A
Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLN-VSHCR-MKPTFVERLREVTTVFGGE-A 4568

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             F   V     P  KI WY +   + +  R     +     L I      DSG Y+C   
Sbjct: 4569 SFSVRVKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILS 4626

Query: 3228 NKYGEDFTRATI 3239
            N  G++  R+ +
Sbjct: 4627 NAVGKETCRSQL 4638



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 30/109 (27%), Positives = 55/109 (50%), Gaps = 3/109 (2%)

Query: 2629 VPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG 2688
            VP+  VD G    P+ T  ++      EG ++  E  V+    P+  +EW++  + L  G
Sbjct: 5039 VPKEEVDHGQIVKPVITRKIRDAQG-EEGSNIRFEIHVKSHPPPH--VEWYRGSIKLAHG 5095

Query: 2689 ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             + + +   G  +L+I  ++ DD+G Y   ATN  G + S A + ++D+
Sbjct: 5096 PKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDK 5144



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 68/253 (26%), Positives = 100/253 (39%), Gaps = 28/253 (11%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F      P  V E + +++  RL   G+P   V W+ +G  +    + K         
Sbjct: 379  PEFADGDLEPIEVKEDQAVNV--RLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHE 436

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTS--------AIVRVIERSDIVTDTQNEQAIEQI 1288
            L I  A++ D G+Y   A N LGS   +         +  VIE   +    + E   +  
Sbjct: 437  LSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWS 496

Query: 1289 --QLLEDAAR-RTKQVRE--------DITVMQA---PQFSRALHNIETVEGTNVHLECRL 1334
                L+DA   + K   E        DI V +A   P+F R + ++  +E   V  E  +
Sbjct: 497  VNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPI 556

Query: 1335 QPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            Q  G     VEW+     IK G RF    + E D  +L +     EDSG Y C A+N  G
Sbjct: 557  Q--GYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAG 614

Query: 1393 EAVTSCALRVIAK 1405
            +      L V  K
Sbjct: 615  KTTALLNLDVNEK 627



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 86/387 (22%), Positives = 156/387 (40%), Gaps = 76/387 (19%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            KP+  + +K+ +  EG        L+    P   +EWY     ++ G R+K + D    +
Sbjct: 1410 KPEVLEKMKDVKGVEGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKYS 1467

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYER 2096
            L I     +D GTY C A+N  G+   T   +++ K   Y    +E++  +  E++   +
Sbjct: 1468 LTIKDLNLQDIGTYKCIASNEAGK--VTQRAELEVKERDYAPIFEEKQFLEPLEIQ-VRQ 1524

Query: 2097 PKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156
            P  +     G+    +T   + + L++G   H E                     IR+G 
Sbjct: 1525 PVEVSYHVRGRPKPTVTWWKNGKELRDG--KHVE---------------------IRSGG 1561

Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNG 2216
             Y T        L IL +  ED+G+Y C A N +G A                       
Sbjct: 1562 TYHT--------LYILRSEEEDAGSYKCLARNDVGSA----------------------- 1590

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276
             E++ +++ +G   + + E PK++     ++LR +  + E       C V+   DP+   
Sbjct: 1591 -ERLFEVQVEG--VKPKEEAPKLT-----SQLR-SARITESDDFELACDVKGTPDPS--Y 1639

Query: 2277 EFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTA 2336
            E+  + K ++       +FD    +L+ +     D G Y+V   NA G   S+ ++    
Sbjct: 1640 EWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANL---- 1695

Query: 2337 KGSIISESQRPEGLEKIRELESAEPFK 2363
               I+    +PE LE +++ E  E  K
Sbjct: 1696 --DIVKSKSKPEILETMKDAEGIETGK 1720



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 82/367 (22%), Positives = 138/367 (37%), Gaps = 25/367 (6%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
            +   EG ++     +   G P   +EW K+GQ +  ++      R  Y +LD+L     D
Sbjct: 3890 IVVREGCEVSMMANVR--GKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQAD 3947

Query: 706  SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE----DYSKY-QHQE 760
            SG Y   A +  G A     L+VT  A  E+ S  P  +  +  L     DY+K+  H  
Sbjct: 3948 SGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSS-PIFVTELSPLSVTEGDYTKFVAHVS 4006

Query: 761  SIEEQTSQRPQFIRPLQDLGELQEGRNAH----FEAQLTPVSDPTMRVEWYKDGRPITAS 816
             +   + Q  +   P+     ++   + H       Q+T       +V    +    T+S
Sbjct: 4007 GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSS 4066

Query: 817  SRITSIFNFGYVSLNIMHLRAED-AGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIP 875
            ++++    +G  ++  ++   E   GS +   V   G  +  A +      T       P
Sbjct: 4067 AKLSVREEYGKPAITQLYRDVEGFDGSESELTVQVSG--VPAAEVEWFRGKTKL----FP 4120

Query: 876  EQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEF-KTPIKDQISIKEGGFAHFEARLE 934
             +R Y                     V E    PEF +   K    ++E GFA+    + 
Sbjct: 4121 SERSY---KIIATNEYGRTGALIDLTVKERLFGPEFIEEDGKWSKIVRERGFANITFMV- 4176

Query: 935  PIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQAT 994
             +G+    V W KDG  +  +SR+          L I  +T  DAG Y C A + +G   
Sbjct: 4177 -LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCF 4235

Query: 995  TSANLTI 1001
             S  L +
Sbjct: 4236 RSCTLDV 4242



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 71/297 (23%), Positives = 114/297 (38%), Gaps = 39/297 (13%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            K +P   + WY +G +L   +R  + S      +++  +   D+G Y C+A ++ G A  
Sbjct: 3407 KGNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIR 3466

Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI 3057
            S    CT    L  +     G E        E  + K    Q D+D              
Sbjct: 3467 S----CT----LEIKVPSMGGPE--------EKKISKALIGQGDND-------------- 3496

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEAS--HRIRTVYAFGMVVLEILGTKT 3115
            V   EG    ++  +  TG     +EW+     +  S  ++I      G+  L +     
Sbjct: 3497 VQAVEGWKVQFQTRI--TGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTK 3554

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQSAHFECTVV 3174
             D GTY C ATN  G +   + L+  DK     P    H    E  + +GQ  + +  VV
Sbjct: 3555 DDIGTYKCLATNSAGSSACRINLDVKDKQYA--PEIPGHEDRQELNVPEGQEINMD--VV 3610

Query: 3175 PVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                P +++ WY +G+ ++ + RI   S      L I      DSG Y C   +  G
Sbjct: 3611 IKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLYKCEGVSTLG 3667



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 46/195 (23%), Positives = 80/195 (41%), Gaps = 9/195 (4%)

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
            G  P++D   P  F         ++EG+    E  +  TG     +EWF N K ++  H 
Sbjct: 4743 GHVPEEDWSAP-SFVIELTPTT-VTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDHL 4798

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ 3156
            +R+ +   ++ L +  T   D+G Y C   N  G A     L  V+++   KP     + 
Sbjct: 4799 VRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLS-VNRAL-TKPEVAEKMT 4856

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
            +I+ + +G     E  V+    P  K+EW+ +   + ++ R           L I     
Sbjct: 4857 DIDAV-EGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCTT 4913

Query: 3217 HDSGEYVCRAYNKYG 3231
            +D+G Y     N+ G
Sbjct: 4914 NDTGPYKVIGTNECG 4928



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 52/204 (25%), Positives = 83/204 (40%), Gaps = 31/204 (15%)

Query: 2000 TLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            T T   +P   V WY +G  +    R  T        L+I    +ED GTYMC+A + +G
Sbjct: 4967 TFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLG 5026

Query: 2060 EAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQ--RPVFLTALTS 2117
            +   +               LD Q + K             EE   GQ  +PV    +  
Sbjct: 5027 KCFRSC-------------ILDVQAVPK-------------EEVDHGQIVKPVITRKIRD 5060

Query: 2118 LENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE 2177
             +  +EG    FE  V+    PH  ++W+    K+  G +Y+ +   G  +L I     +
Sbjct: 5061 AQG-EEGSNIRFEIHVKSHPPPH--VEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKD 5117

Query: 2178 DSGTYMCKATNKLGEAVNTCTLKV 2201
            D+G+Y   ATN+ G + +   + V
Sbjct: 5118 DTGSYKVVATNQAGSSTSRAEVVV 5141



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P F   L  IE  EG +  L C +   G     V+WF +   IK   RF+ +Y+ +  AL
Sbjct: 1021 PTFMSKLEPIEITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 1078

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
             +     +D GVY C  TN  G +V+S A   + KK L
Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFG-SVSSKADVTVLKKHL 1115



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 50/207 (24%), Positives = 81/207 (39%), Gaps = 13/207 (6%)

Query: 383  IEISEKALAPQFVKVCQ--DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            + + E+   P+F++      + V E         V G P P V WF +  Q+ +     +
Sbjct: 4142 LTVKERLFGPEFIEEDGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDM 4201

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI-------EKEQVVAPKF 493
               +S  + L I  +T  D+G   C AR++ G     C L+V         + Q   P+ 
Sbjct: 4202 RSRDSLQY-LNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVKAVRPRRGNEVQACKPQ- 4259

Query: 494  VERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI--HTDGGASTLDIP 551
              + + +   EG  V L+ R  G P P + W +    I      +     D G  +L I 
Sbjct: 4260 TSKMANVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIIS 4319

Query: 552  RAKASDAAWYQCTAQNVAGSTATRARL 578
              +  D+  Y+  A N  G   T A L
Sbjct: 4320 DVQLEDSGSYRAVASNNLGEATTLAEL 4346



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 12/157 (7%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLEC---VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173
            D G Y C ATN+ G+A +   L+    V +     P F   +     + +G+S   E  +
Sbjct: 4718 DGGLYKCVATNEHGEASMLFNLDVEGHVPEEDWSAPSFVIELTPTT-VTEGESTALEVEI 4776

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
                 P  K+EW+ N +P++H   +++  D   + L +  T   D+G Y C   N  G  
Sbjct: 4777 TGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTA 4834

Query: 3234 FTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQ 3270
             + A ++      V     +P+   K+ ++++++G +
Sbjct: 4835 SSMADLS------VNRALTKPEVAEKMTDIDAVEGTE 4865



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 3/94 (3%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F+ +L  PT ++EG+S   E  I   P P  +VEW+ N K ++  H  R+  D    
Sbjct: 4752 APSFVIELT-PTTVTEGESTALEVEITGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVI 4808

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             L +     ED+G Y C  +N+LG A S   L+V
Sbjct: 4809 RLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F+ ++   T + EG+S   E  +     P  KVEWF N K + H H  R++ D  ++ 
Sbjct: 4753 PSFVIELTPTT-VTEGESTALEVEITGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVIR 4809

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            L +     E++G Y C   N LG  S+ A+L
Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMADL 4840



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 11/147 (7%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F   L  ++ L EGD   F   +  +  P   ++W+ + + +   HR RT  D   V 
Sbjct: 5544 PAFTAPLQHIDIL-EGDTTRFIGEITGVPVP--VVEWYRDDRPVTRDHRLRTYSDGRVVI 5600

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA-QG 2227
            L +  T   D+G + C   N LG   ++ +L      N+      P   EK++++EA +G
Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASL------NVNEGYSKPEINEKLKKIEAFEG 5654

Query: 2228 HSTRIEVEEPKISPPRFVTELRGTTHV 2254
               R ++      PPR V   RGTT +
Sbjct: 5655 GEARFDLLVTGFPPPR-VDWYRGTTKI 5680



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F   ++ + V E+++A F   +   G P  R++W  N  P+   +R+ T  D     
Sbjct: 4454 APGFKSALRSLDVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            L +     +D+G Y C A+N+ G A +++ L V
Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 52/200 (26%), Positives = 84/200 (42%), Gaps = 28/200 (14%)

Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
            +P   V WY +G +L    R  T +      L+I ++  ED+G Y C+A + LG+     
Sbjct: 4973 NPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCF--- 5029

Query: 1933 RLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEG 1992
                    S I D Q   A+ K +              D   + KP   + I++A+  EG
Sbjct: 5030 -------RSCILDVQ---AVPKEEV-------------DHGQIVKPVITRKIRDAQGEEG 5066

Query: 1993 HPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMC 2052
              +  E  +   + P   VEWY     +  G +++ +   G  +L I     +DTG+Y  
Sbjct: 5067 SNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKV 5124

Query: 2053 KATNAVGEAVTTSSVKVDAK 2072
             ATN  G + + + V V  K
Sbjct: 5125 VATNQAGSSTSRAEVVVKDK 5144



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 66/247 (26%), Positives = 96/247 (38%), Gaps = 30/247 (12%)

Query: 1584 LKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCL 1643
            L+ +E+KE Q  +   RL    +   +V WY +   L    +           L I    
Sbjct: 386  LEPIEVKEDQAVNV--RLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKAS 443

Query: 1644 PEDSGTYTCRAINALGE--------AVTSGIAIVHSKKSIYLESQHE-GALPRLNQ-LED 1693
              D G Y C A N LG          V  G+A V     + L+ + E GA   +N  L+D
Sbjct: 444  TNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDD 503

Query: 1694 TSKYQRH---------SAQDEVITQA---PVFTMPMKDIRVAENQAAHFEARLIPV-GDP 1740
              +Y+           S  D  + +A   P F   ++D+   E +   FE   IP+ G P
Sbjct: 504  AGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFE---IPIQGYP 560

Query: 1741 KLRVEWLRNGVPIEASNRLTTMH--DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
            +  VEW R    I+   R T     +    +L +     EDSG Y C A N+ G+     
Sbjct: 561  RPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALL 620

Query: 1799 TLFVQSK 1805
             L V  K
Sbjct: 621  NLDVNEK 627



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 3/114 (2%)

Query: 753 YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRP 812
           +  +  +  + E   + P     + D+  + +G +      +T   +P   VEW+KDG+P
Sbjct: 713 FRSFDIKVKVAEPQGETPTITTEMTDIQAI-DGEDCKLICHVT--GEPNPEVEWFKDGKP 769

Query: 813 ITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           + A+ R+   F    ++L+   ++ ED G Y     N  G   S A ++V  RS
Sbjct: 770 LKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS 823



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 30/88 (34%), Positives = 44/88 (50%), Gaps = 2/88 (2%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            I+ + +  C E +   F C  E S  P  +IEWF    P+  G R+  T + +  SL I+
Sbjct: 829  ITSMRDCDCVEEETASFHC--EFSGKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAIS 886

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSLR 2864
                ED+G Y C A+N+ G  TT   L+
Sbjct: 887  DLKLEDAGNYKCVASNAAGKTTTRAELK 914



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F   L+ I+ I EG      C +   G P  +V+WFR+E LI+ S R   ++D    +
Sbjct: 1021 PTFMSKLEPIE-ITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 1077

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            +T+     +D+GVY C  +N  G
Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFG 1100



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 65/260 (25%), Positives = 113/260 (43%), Gaps = 27/260 (10%)

Query: 907  QKPEFKTPIKDQISIKEGGFAHFEARL--EPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            + P F   ++   +I+E     F+++L     G    +++W K+G+PVE+  R+ T ++ 
Sbjct: 2933 EAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYD- 2986

Query: 965  GYVA-LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYL 1023
            G VA L+I  V+  DAG Y C A NA G  ++SA LT V+++++     H         L
Sbjct: 2987 GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALT-VSRRNMRPLITHK--------L 3037

Query: 1024 EDASRY-SKRTEEEVKITQKPR-FLGPLKGTNKIVEGQSAHFEARVEP------QSDLTM 1075
             D   Y  K    ++++T  P   +   KG + I EG+     +  E        SDL  
Sbjct: 3038 HDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNA 3097

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
              +  +       A +  T      +A D      E+     V+  N   EAQ+  S+  
Sbjct: 3098 DDDGIYKCVAQNLAGKASTRAMLDVIARDFGPEFDEEESPKPVIV-NEGEEAQMMVSVRG 3156

Query: 1136 ETRSSIDTSSIHRGLYEKTR 1155
              ++ ++     + LY+  R
Sbjct: 3157 RPKAVVEWFKDGKFLYDSRR 3176



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 3/94 (3%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F + L     ++E +SA + C +   P P  R++W+ N + +    R  TS+D    
Sbjct: 4454 APGFKSALRS-LDVTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPVH 4510

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             L I     +D+G Y C A+N+ G A S+  LNV
Sbjct: 4511 KLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 29/199 (14%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G+P  ++ W K+G  +  ++R  +  R     L++ SL  +D+G Y C A S  G     
Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031

Query: 724  AVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQ 783
             +L V  +A  +    H + +                        +P   R ++D  + +
Sbjct: 5032 CILDV--QAVPKEEVDHGQIV------------------------KPVITRKIRD-AQGE 5064

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
            EG N  FE  +   S P   VEWY+    +    +       G  SL I  ++ +D GSY
Sbjct: 5065 EGSNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSY 5122

Query: 844  TVRAVNKLGEAISTASIRV 862
             V A N+ G + S A + V
Sbjct: 5123 KVVATNQAGSSTSRAEVVV 5141



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 56/200 (28%), Positives = 84/200 (42%), Gaps = 28/200 (14%)

Query: 2138 DPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
            +P   + W+ +G  +    R  T        L+I    +ED+GTYMC+A +KLG+   +C
Sbjct: 4973 NPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSC 5032

Query: 2198 TLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEG 2257
                      ILD Q    + K    E   H    ++ +P I+  R + + +G     EG
Sbjct: 5033 ----------ILDVQ---AVPK----EEVDHG---QIVKPVIT--RKIRDAQGE----EG 5066

Query: 2258 KTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSV 2317
                FE  V+  H P   +E+Y     L    ++ I+   G  SL I     +D G Y V
Sbjct: 5067 SNIRFEIHVKS-HPPP-HVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKV 5124

Query: 2318 KAINALGHCTSAISMTVTAK 2337
             A N  G  TS   + V  K
Sbjct: 5125 VATNQAGSSTSRAEVVVKDK 5144



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 3/93 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F  PLQ + ++ EG    F  ++T V  P   VEWY+D RP+T   R+ +  +   V 
Sbjct: 5544 PAFTAPLQHI-DILEGDTTRFIGEITGVPVPV--VEWYRDDRPVTRDHRLRTYSDGRVVI 5600

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            L +      DAG +     N LG   S+AS+ V
Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 24/66 (36%), Positives = 34/66 (51%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   +EW+C   P+  G RF  T +    +L I     ED G Y C A+NA G+  T + 
Sbjct: 853  PEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAE 912

Query: 2067 VKVDAK 2072
            +KV+ K
Sbjct: 913  LKVNEK 918



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 59/255 (23%), Positives = 108/255 (42%), Gaps = 41/255 (16%)

Query: 1276 VTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ---APQFSRALHNIETVEGTNVHLEC 1332
            ++D + E A     +  +AA +T   R ++ V +   AP+F      I+ ++G +V++  
Sbjct: 885  ISDLKLEDAGNYKCVASNAAGKTT-TRAELKVNEKHFAPEFEDWKDTIDALDGQDVNIST 943

Query: 1333 RLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
             ++  G     + W  +G+ ++     +     D   L L  V PED+G+YTC+A N  G
Sbjct: 944  WVR--GKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAG 1001

Query: 1393 EAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKS 1452
                      I  KD+ +       +E +Q   DT                P F+++ + 
Sbjct: 1002 ----------IVSKDVTIT------VEALQKKGDT----------------PTFMSKLEP 1029

Query: 1453 IENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE 1512
            IE + EG      C +        +V+WF++   +    RF+  +D    AL + +   +
Sbjct: 1030 IE-ITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELD 1086

Query: 1513 DSGIYTCRAVNLVGT 1527
            D G+Y C   N  G+
Sbjct: 1087 DDGVYKCVVTNNFGS 1101



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+S L  I   EGD+    CNV     P  +++WF +   +    R+K+++D +  +L +
Sbjct: 1023 FMSKLEPIEITEGDDFQLSCNVTGRPQP--EVQWFRDEVLIKPSRRFKASYDGNVSALTV 1080

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 +D G+Y C  TN+ GS ++   +
Sbjct: 1081 KEAELDDDGVYKCVVTNNFGSVSSKADV 1108



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 75/334 (22%), Positives = 131/334 (39%), Gaps = 40/334 (11%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIE--ASHRIRTVYAFGMVVLEILGTKTTD 3117
            I EG  + ++  +   G  +  +EWFY  + +     +RI +    G+  L +   +   
Sbjct: 2540 IVEGNDSRFDVRI--RGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597

Query: 3118 SGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHF-ECTVVPV 3176
            +G Y   A+N+ G+A+  + L   ++     P F     + E  K  +   F   T   +
Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTVNERLYA--PEFLE--DDGEWSKVVRKGGFVNITFTLM 2653

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
             +P   + WY +G  +  ++R    S       +I +    D+G YVC A+N+ G  F  
Sbjct: 2654 GNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRS 2713

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
             TI                   +I+E +S+     + P        KF     D  + V 
Sbjct: 2714 CTI-------------------EIKEPKSVDSTDTRAPGQLIPVKHKF-----DF-EGVP 2748

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF--HDFGIVILDILYCYEENSGE 3354
            G  A  +  LV   D  + +EWF     L  G +Y+     D   + L +     E++G 
Sbjct: 2749 GGKARCDV-LVKKSD-IIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGT 2806

Query: 3355 YECVATNKLGRDSTKANLKCTSKEN--LILDSQL 3386
            Y CV     G+ + +  L    K+   L LD ++
Sbjct: 2807 YRCVVHTPAGQTTIRGELHIKEKQQAPLFLDEKV 2840



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 64/265 (24%), Positives = 104/265 (39%), Gaps = 34/265 (12%)

Query: 3819 APKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878
            APKE+    + P F+T++   +V E +  +F   V     P   I+WY++   + S HR 
Sbjct: 3974 APKEK---WSSPIFVTELSPLSVTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRI 4028

Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPR 3935
            RT +D   V L I  +  ED G+Y     N+ G   + A +S ++    P I    +   
Sbjct: 4029 RTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVE 4088

Query: 3936 GMKRSEA----------------------LTQMEATIKKYTSEVYLTEDDLYDVDKKQ-- 3971
            G   SE+                      L   E + K   +  Y     L D+  K+  
Sbjct: 4089 GFDGSESELTVQVSGVPAAEVEWFRGKTKLFPSERSYKIIATNEYGRTGALIDLTVKERL 4148

Query: 3972 -PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
              P F+ +   + S +  E          +G+P   V WF +G  L   +R         
Sbjct: 4149 FGPEFIEE-DGKWSKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSL 4207

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYG 4055
              +N   + P+D+G Y+C A +  G
Sbjct: 4208 QYLNIFGLTPDDAGTYVCEARSRLG 4232



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 61/260 (23%), Positives = 106/260 (40%), Gaps = 35/260 (13%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            +F++ L+ +   EGD   F  +V  S  P   I+W+ ++ P+ S  R ++  D   V L 
Sbjct: 3983 IFVTELSPLSVTEGDYTKFVAHV--SGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLL 4040

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGD------KNIYFDTQHPQGKAGLEAVE 2888
            I     ED G Y     N  GSAT+S  L    +        +Y D +   G      V+
Sbjct: 4041 IGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVEGFDGSESELTVQ 4100

Query: 2889 ----QAEEARLAKGRR---PS------VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQ- 2934
                 A E    +G+    PS      +   EY +   +I +  + +L   + +  +G+ 
Sbjct: 4101 VSGVPAAEVEWFRGKTKLFPSERSYKIIATNEYGRTGALIDLTVKERLFGPEFIEEDGKW 4160

Query: 2935 ---VEPK----------NDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
               V  +           +P   + W+ +G  L + SR  + S      L++  +   D+
Sbjct: 4161 SKIVRERGFANITFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDA 4220

Query: 2982 GIYTCKAYNKRGEAFTSSTV 3001
            G Y C+A ++ G  F S T+
Sbjct: 4221 GTYVCEARSRLGTCFRSCTL 4240



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 3/100 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V +S   P FK+ ++  + + E   A F  R E  G    R++W  + +PV   SRI T 
Sbjct: 4448 VCKSALAPGFKSALRS-LDVTEDESAEF--RCEVSGSPAPRIQWFMNDQPVSRDSRIITS 4504

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             +     L I   T+ D G Y C A N  G AT++A+L +
Sbjct: 4505 SDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 48/156 (30%), Positives = 68/156 (43%), Gaps = 17/156 (10%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F +AL SL+ + E + A F C V     P   I WF N Q +    R  T+ D     
Sbjct: 4455 PGFKSALRSLD-VTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA--- 2225
            L I     +D+G Y C A N  G A +T  L V+  R        P  +E++R++     
Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCR------MKPTFVERLREVTTVFG 4565

Query: 2226 --QGHSTRIE-VEEPKISPPRFVTEL--RGTTHVFE 2256
                 S R++    PKI   + +T L  RG  H+ E
Sbjct: 4566 GEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISE 4601



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F   +++ +VTE         ++    P  R++W+ N +PV +  R  T+ D     L
Sbjct: 4455 PGFKSALRSLDVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKL 4512

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             I  A  +DTG Y C A N  G A +T+ + V
Sbjct: 4513 AITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 3/102 (2%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            E   KAP F   L   +N REG+   F  ++T   +P  ++EW  +G S+++  R  T+ 
Sbjct: 5243 EAAPKAPAFLKQLLP-QNAREGDVVKFSCKVTGYPEP--EIEWTRDGVSMESDERVTTWY 5299

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            D     L I      DSG Y C   NN G A ++A + V GK
Sbjct: 5300 DGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK 5341



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 50/196 (25%), Positives = 86/196 (43%), Gaps = 36/196 (18%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG+P++A  R+   F+     L IK V   D G Y     N +G  +++A+L + 
Sbjct: 216  ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVT 275

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062
             K    A+ +    +E ++ +E +  +      EVK    P           I + +  H
Sbjct: 276  PKP---AKPEVVRKMENVESVEGSDAFF-----EVKFKGYP-----------IPKREWFH 316

Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
               ++EP S   +T +   + +Q +S              L I+ +R +DSG Y  +A N
Sbjct: 317  DSKKIEPSSRFKITTD---DTEQTSS--------------LVISDLRLDDSGAYQCIASN 359

Query: 1123 AAGEAQLSASMTVETR 1138
             AGE  L A + V+ +
Sbjct: 360  EAGECNLRADLKVKNK 375



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 33/87 (37%), Positives = 47/87 (54%), Gaps = 5/87 (5%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            +P   + ++N++++ EG  A F+ +    G P  K EWF + K IE SSR   T D    
Sbjct: 280  KPEVVRKMENVESV-EGSDAFFEVKF--KGYPIPKREWFHDSKKIEPSSRFKITTDDTEQ 336

Query: 2435 --SMTISHVRDEDEGVYMCRASNLLGE 2459
              S+ IS +R +D G Y C ASN  GE
Sbjct: 337  TSSLVISDLRLDDSGAYQCIASNEAGE 363



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 68/267 (25%), Positives = 108/267 (40%), Gaps = 20/267 (7%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            +E  E      R+    +PK  + WY++G  L    + +         L I      D G
Sbjct: 389  IEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEG 448

Query: 3901 EYICRAVNDFG--EDFTKATISCKKLPDIILQNQVP-RGMKRSEALTQMEATIK------ 3951
            +Y C A N  G  +   K T+  K +  +I    +P +  K + A   +  T+       
Sbjct: 449  QYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYK 508

Query: 3952 -KYTSEV-YLTEDDLYDVDK-KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVE 4008
             K T+EV  +T     +V K K  P F+ +++  T+L E E   FE  +   G P   VE
Sbjct: 509  VKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQ--GYPRPIVE 565

Query: 4009 WFFNGKPLLHKNRFT--PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
            W+     +    RFT     +    ++       EDSG Y C A+N  G  +T A++   
Sbjct: 566  WYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAG--KTTALLNLD 623

Query: 4067 GKPGIVYDSQLPKHMKSIEKIREMEAS 4093
                +V   +  K +K IE     EA+
Sbjct: 624  VNEKVV-QPEFDKEVKPIEVKHGEEAT 649



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 27/85 (31%), Positives = 47/85 (55%), Gaps = 2/85 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+SHLN++   EGD+    C +    +PT  +EWF +++ + +  R +S+   +  +L  
Sbjct: 3689 FLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTLIF 3746

Query: 2836 THTYEEDSGIYTCKATNSKGSATTS 2860
                 +D G Y C ATN +GS ++S
Sbjct: 3747 ETVNIQDRGAYRCTATNQEGSTSSS 3771



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 13/162 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F T    +  ++EG    + A +  +G     I+W+ +   I ++HRIRT +  G VV
Sbjct: 3982 PIFVTELSPL-SVTEGDYTKFVAHV--SGVPLPSIQWYKDDNPISSNHRIRTFFD-GHVV 4037

Query: 3108 LEILGTKT-TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
              ++G  T  D G Y     N+ G A  S KL  V +  G KP  T   +++EG    +S
Sbjct: 4038 KLLIGQITLEDQGQYKVVLKNESGSATSSAKLS-VREEYG-KPAITQLYRDVEGFDGSES 4095

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQ---PMRHSTRIKTVSDFG 3205
               E TV     P  ++EW+       P   S +I   +++G
Sbjct: 4096 ---ELTVQVSGVPAAEVEWFRGKTKLFPSERSYKIIATNEYG 4134



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 80/359 (22%), Positives = 137/359 (38%), Gaps = 31/359 (8%)

Query: 1077 VEWYFNGKQITSANRIQT--YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            VEW+   ++IT   R +T    D G  +L I+ V+ EDSG Y  VA N  GEA   A +T
Sbjct: 4288 VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELT 4347

Query: 1135 VETR---SSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSE 1191
            V+ +     ++    H  L  +   +   K + P +  + I     + ++        S 
Sbjct: 4348 VKGKHFARELEEGGCHSRLTFRKGQMVSVKAIVPAHPKQVIWYKDGIRLEDSRRVNLRSV 4407

Query: 1192 GKNIHL---ECRLEPMG----DPTMRVEWFHNGRSVTVGSRFKTYYDFGFV----ALDII 1240
            G+  ++       E  G    + T   E       + +    K+    GF     +LD+ 
Sbjct: 4408 GERYYVVVPSASFEDSGIYKCETTSEKETTSQLFDIHIEDVCKSALAPGFKSALRSLDVT 4467

Query: 1241 HATSAD-----TGEYTVRAVNHLGSAHTSAIVRVIERSD-------IVTDTQNEQAIEQI 1288
               SA+     +G    R    +     S   R+I  SD       I   T  +  + + 
Sbjct: 4468 EDESAEFRCEVSGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKC 4527

Query: 1289 QLLEDAARRTKQVREDIT-VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWF 1347
              + D    T     +++     P F   L  + TV G       R++  G    ++ W+
Sbjct: 4528 LAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGEASFSVRVK--GFPRPKIVWY 4585

Query: 1348 CNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
             +   +    RF  + E D   L + +V  +DSG Y C  +N +G+      L V A++
Sbjct: 4586 KDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEE 4644



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDF 3612
            +S   P F +    L ++E+ SA F C +      + R++WF N +P+   SR+ T +D 
Sbjct: 4450 KSALAPGFKSALRSLDVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDG 4507

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                L I     +D G+Y C A N +G AT +  L V
Sbjct: 4508 PVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 7/151 (4%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVN-QAPRFITQLNGPTKLSEGQSAHYE 1865
            S+   + ++S   K +         R  DV V V  +AP   ++L  P K+ EG+   + 
Sbjct: 147  SIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELK-PDKVQEGEQYKFT 205

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C +   P P   + WY +G+ +++  R + S D   + L I  V  +D G Y  +  N+L
Sbjct: 206  CAVTGKPKPV--ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDL 263

Query: 1926 GQAVSSIRLNV---QSKESIIRDSQHESALE 1953
            G   S+  L V    +K  ++R  ++  ++E
Sbjct: 264  GSISSTADLEVTPKPAKPEVVRKMENVESVE 294



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 2/98 (2%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            + P  T  M DI+  + +       +   G+P   VEW ++G P++A++RL    +   +
Sbjct: 728  ETPTITTEMTDIQAIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMI 785

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
            AL+ + +  ED G Y C   N  G   +++ + V+ ++
Sbjct: 786  ALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS 823



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 3/97 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+ + +++DV K VEG  A F  +L     PD  +EW+Y   ++  G RY+   D     
Sbjct: 1411 PEVLEKMKDV-KGVEGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKYS 1467

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            L I     ++ G Y+C+A+N+ G+ + +A L+   ++
Sbjct: 1468 LTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKERD 1504



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 50/238 (21%), Positives = 96/238 (40%), Gaps = 11/238 (4%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P+F   L  P  + EG +  +  +V  +  P++  EWY +   L+  +R++   D   
Sbjct: 2190 EAPVFVSKLR-PLFVTEGDNVSWMCKVAGMPRPTV--EWYRDNQPLRADTRWKMDFDGRV 2246

Query: 2566 VTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXX---XIIDQAMRPESWEQIQLK 2622
             +L ++     D G+Y C   N AG                  +I++    ++ E  + +
Sbjct: 2247 CSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEAR 2306

Query: 2623 -EAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVY----LEAQVEPRTDPNLKIE 2677
             +   + +P   V        +        D+L E   V     +  +V  R  P   I 
Sbjct: 2307 FDVRFSGLPRPEVTWYRNSIKVRNEKFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIV 2366

Query: 2678 WFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            W+K+G  +    R +      + T +  S   +D+G YTC+A+N LG+     ++ ++
Sbjct: 2367 WYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLGKCSRDFNLHVD 2424



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 3/117 (2%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            +EK  +P+F   LS + ++ EG+   F A ++    P+  ++WY +   + +  R RTF 
Sbjct: 3976 KEKWSSPIFVTELSPL-SVTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFF 4032

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEG 3530
            D   V L I     ED G+Y     N  G A ++A + V+ +      +QL + +EG
Sbjct: 4033 DGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVEG 4089



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 1/116 (0%)

Query: 4085 EKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            E   E E + Q+    + +  K+   P F S   ++ V E E A F C V+G P PR+ W
Sbjct: 4429 ETTSEKETTSQLFDIHIEDVCKSALAPGFKSALRSLDVTEDESAEFRCEVSGSPAPRIQW 4488

Query: 4145 LLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199
             +N   +   SR   + DG  H   I K    DTG  + +             L V
Sbjct: 4489 FMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 36/121 (29%), Positives = 59/121 (48%), Gaps = 6/121 (4%)

Query: 1169 IEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228
            + E   S P FV  L+ P  V+EG++  LE  +E  G P  +VEWF N + V      ++
Sbjct: 4745 VPEEDWSAPSFVIELT-PTTVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRS 4801

Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA---IVRVIERSDIVTDTQNEQAI 1285
            Y+D   + L +   T  D G Y    +N LG+A + A   + R + + ++     +  A+
Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAV 4861

Query: 1286 E 1286
            E
Sbjct: 4862 E 4862



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 2/94 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F+ ++   TV E E    E  VE    P  ++EW++N K +   H  R+ +D   + L
Sbjct: 4753 PSFVIELTPTTVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRL 4810

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             +     ED+G Y C  +ND G   + A +S  +
Sbjct: 4811 IVRRTTLEDAGLYRCTILNDLGTASSMADLSVNR 4844



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F   +    VTEG    LE  +T    P  +VEW+ N +PV+  H  ++ +D   + L
Sbjct: 4753 PSFVIELTPTTVTEGESTALEVEIT--GTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRL 4810

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             +     ED G Y C   N +G A + + + V+
Sbjct: 4811 IVRRTTLEDAGLYRCTILNDLGTASSMADLSVN 4843



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 10/143 (6%)

Query: 903  PESTQK-PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            PE+  K P F   +  Q + +EG    F  ++   G     +EW +DG  +E+  R+TT+
Sbjct: 5242 PEAAPKAPAFLKQLLPQ-NAREGDVVKFSCKVT--GYPEPEIEWTRDGVSMESDERVTTW 5298

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            ++  +  L+I +    D+G Y C   N  G A++SA L +  K      +Q P   + ++
Sbjct: 5299 YDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK------TQRPRLSDNMK 5352

Query: 1022 YLEDASRYSKRTEEEVKITQKPR 1044
             L        R E  +K T KP+
Sbjct: 5353 ELFATVGGEARFEVTMKATPKPK 5375



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 14/122 (11%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF--KTTYDFGYVALDILYAYAE 2045
            EV EG  V+L+ T+T    P   V WY +G+P+++      K+T D  +  L I  A   
Sbjct: 99   EVFEGESVNLDLTIT--GKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF--LSIPKATPN 154

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE-------RPK 2098
            D+G Y C+A N +G +     V V  K G       E +  K+QE E+Y+       +PK
Sbjct: 155  DSGKYKCEAKNKIGTSARDFDVNVKVK-GKAPTVTSELKPDKVQEGEQYKFTCAVTGKPK 213

Query: 2099 PI 2100
            P+
Sbjct: 214  PV 215



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 2/105 (1%)

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            +V  E ++  P V  S+ D   VEE E A F C  +G P+P + W    N IV G R+ +
Sbjct: 816  EVKVEDRSLKPEVITSMRDCDCVEE-ETASFHCEFSGKPEPEIEWFCGPNPIVPGGRFHV 874

Query: 4160 TYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRH 4203
            T +G +    I   +  D G  + +             LKV  +H
Sbjct: 875  TEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEKH 919



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 35/201 (17%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            V W+ N K L+ G      +   +  L I+    ED+G+Y C A N +G           
Sbjct: 1540 VTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVG----------- 1588

Query: 1671 SKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHF 1730
            S + ++ E Q EG  P+                     +AP  T  ++  R+ E+    F
Sbjct: 1589 SAERLF-EVQVEGVKPK--------------------EEAPKLTSQLRSARITESD--DF 1625

Query: 1731 EARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINE 1790
            E      G P    EWL++  P++    L++  D     LN K V   D G+YT    N 
Sbjct: 1626 ELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNA 1685

Query: 1791 LGEAVTSSTL-FVQSKASLQL 1810
             G   +S+ L  V+SK+  ++
Sbjct: 1686 HGSTYSSANLDIVKSKSKPEI 1706



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 3/101 (2%)

Query: 2634 VDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            V  G +  P F +HL S D + EG    L  ++  + +P   +EWFK+   +T   R++S
Sbjct: 3679 VPDGSRVTPKFLSHLNSLD-VDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRS 3735

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +      TL   ++   D G Y C ATN  G   S+A I +
Sbjct: 3736 SVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVV 3776



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 48/188 (25%), Positives = 73/188 (38%), Gaps = 14/188 (7%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+F +    + D+ EG  A     +   G     +EWF + + I  + R+R+        
Sbjct: 3687 PKFLSHLNSL-DVDEGDSAKLTCKMF--GKPEPTVEWFKDDQLITNNDRVRSSVVGNTCT 3743

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L        D G Y C ATN+ G    S  +  V       PR     ++++ + DG  A
Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVI--VVNRASITPRIIEKPRDVDAV-DGTDA 3800

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPM--RHSTRIKTVSD-FGFVVLDIAYTQNHDSGEYVC 3224
             F  TV     P  K+ W+H    +  R    I  V D +  V+  + Y      G Y C
Sbjct: 3801 KF--TVRVEGFPQPKVTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLH---VGTYKC 3855

Query: 3225 RAYNKYGE 3232
             A N  G+
Sbjct: 3856 IATNDAGK 3863



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 62/228 (27%), Positives = 95/228 (41%), Gaps = 41/228 (17%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF-GYV 2035
            KP+  + +K  E  EG     +  +T    P  RV+WY     +   +R+ +T    G  
Sbjct: 5639 KPEINEKLKKIEAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMA 5696

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
            +L I     ED G Y C A N  GE   T+S+ VD   G                 EK+ 
Sbjct: 5697 SLTIRKIRQEDGGLYGCVAVNEYGE---TTSI-VDLHVG-----------------EKHY 5735

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI-RA 2154
             P+  EEE           L   +  ++G+ A     V    +P   + W+ +G  +   
Sbjct: 5736 GPEFAEEE-----------LDWSKTARKGENARITFTVS--GNPRPDVVWYKDGMLLFDT 5782

Query: 2155 GH-RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             H   R+  D  Y  L I     +D+GTY+C+A ++LG++  T  LKV
Sbjct: 5783 THVDMRSRGDIQY--LTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKV 5828



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 31/86 (36%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT-HDFGY 2433
            +P   + L+ I+  + G+ A FD  L+  G P  +V+W+R    I D +R + T    G 
Sbjct: 5639 KPEINEKLKKIEAFEGGE-ARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGM 5695

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             S+TI  +R ED G+Y C A N  GE
Sbjct: 5696 ASLTIRKIRQEDGGLYGCVAVNEYGE 5721



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT-TMHDFGYVA 1769
            P     +K I   E   A F+  L+  G P  RV+W R    I   NR + T+   G  +
Sbjct: 5640 PEINEKLKKIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMAS 5697

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            L ++ +  ED G Y C A+NE GE  +   L V  K
Sbjct: 5698 LTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 5/106 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFN-GKVLQSGHRYRTSNDFGFAALDILTVYGEDSGE 1916
            E   A ++  IE YP P   VEWY    K+  SG      +D G  +L I  +  +D+G 
Sbjct: 4    ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61

Query: 1917 YTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
            Y C A N+ GQ  +S+R ++  KE  I     E   E I+  E +S
Sbjct: 62   YKCVATNDAGQ--TSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGES 105



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 2/95 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P+   ++ + + VE       C     G     +EWFC   PI  G RF    E +  +L
Sbjct: 826  PEVITSMRDCDCVEEETASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSL 883

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
             +  +  ED+G Y C A+N  G+  T   L+V  K
Sbjct: 884  AISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 32/84 (38%), Positives = 43/84 (51%), Gaps = 4/84 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN--DFGFAALDILTVYGEDSG 1915
            EG     + R+  YP P   VEW+   + +  G RY+T+   D G  +L I  V  EDSG
Sbjct: 4270 EGWKVQLDTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSG 4327

Query: 1916 EYTCKAINNLGQAVSSIRLNVQSK 1939
             Y   A NNLG+A +   L V+ K
Sbjct: 4328 SYRAVASNNLGEATTLAELTVKGK 4351



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F   L      EG +  LE  +   G    +VEWF N KP+K  H  R  ++   + 
Sbjct: 4752 APSFVIELTPTTVTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIR 4809

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L +     ED+G+Y C   N LG A +   L V
Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 50/202 (24%), Positives = 84/202 (41%), Gaps = 29/202 (14%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G+P+  V W ++G  +  + R+ T        LN+  +  ED+GTY C            
Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMC------------ 5019

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857
                   +A  +L     S +  +Q +        +E+V+      P  IT+     +  
Sbjct: 5020 -------EARSKLGKCFRSCILDVQAVP-------KEEVDHGQIVKP-VITRKIRDAQGE 5064

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG +  +E  ++ +P P+  VEWY     L  G +Y+ S   G  +L I  V  +D+G Y
Sbjct: 5065 EGSNIRFEIHVKSHPPPH--VEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSY 5122

Query: 1918 TCKAINNLGQAVSSIRLNVQSK 1939
               A N  G + S   + V+ K
Sbjct: 5123 KVVATNQAGSSTSRAEVVVKDK 5144



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 20/65 (30%), Positives = 36/65 (55%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G+    VEW KDG+P++A+ R+   F    +AL+ + + + D G Y C   N  G  +++
Sbjct: 755  GEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSA 814

Query: 997  ANLTI 1001
            A + +
Sbjct: 815  AEVKV 819



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 2/94 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F+++++   + E +  +  C V  +  P+  ++W+R+  L+    R++  YD    +L
Sbjct: 1021 PTFMSKLEPIEITEGDDFQLSCNVTGRPQPE--VQWFRDEVLIKPSRRFKASYDGNVSAL 1078

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             +     +D G Y C   N+FG   +KA ++  K
Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLK 1112



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSA--NRIQTYHDFGYVALDIASVRAED 1112
            IVEG  + F+ R+      T  VEW++  +++T     RI++  + G  +L ++ V+ + 
Sbjct: 2540 IVEGNDSRFDVRIRGHP--TPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597

Query: 1113 SGVYTVVARNAAGEAQLSASMTVETR 1138
            +G Y +VA N  G+AQ    +TV  R
Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTVNER 2623



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 55/211 (26%), Positives = 87/211 (41%), Gaps = 33/211 (15%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            TVEW+ +G+ +++ N +       Y  LD+      DSG Y  VA N  G A    ++ V
Sbjct: 3911 TVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNLNV 3970

Query: 1136 ETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
                              T    + K+  P++ + E+S        PLS    V+EG   
Sbjct: 3971 ------------------TAIAPKEKWSSPIF-VTELS--------PLS----VTEGDYT 3999

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
                 +   G P   ++W+ +   ++   R +T++D   V L I   T  D G+Y V   
Sbjct: 4000 KFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLK 4057

Query: 1256 NHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286
            N  GSA +SA + V E       TQ  + +E
Sbjct: 4058 NESGSATSSAKLSVREEYGKPAITQLYRDVE 4088



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 7/135 (5%)

Query: 1006 DIIAESQHPGGLEKIQYLED-ASRYSKRTEEEVKITQKPRFLGPLKGTN----KIVEGQS 1060
            D++  +Q   G  K     D  S Y         I  K ++  P+  T      + EG  
Sbjct: 3939 DLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTELSPLSVTEGDY 3998

Query: 1061 AHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVA 1120
              F A V        +++WY +   I+S +RI+T+ D   V L I  +  ED G Y VV 
Sbjct: 3999 TKFVAHVSGVP--LPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVL 4056

Query: 1121 RNAAGEAQLSASMTV 1135
            +N +G A  SA ++V
Sbjct: 4057 KNESGSATSSAKLSV 4071



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            +P F+T+L+ P  ++EG    +   +   P P+  ++WY +   + S HR RT  D    
Sbjct: 3981 SPIFVTELS-PLSVTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFFDGHVV 4037

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
             L I  +  ED G+Y     N  G A SS +L+V+ +
Sbjct: 4038 KLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREE 4074



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 60/204 (29%), Positives = 83/204 (40%), Gaps = 31/204 (15%)

Query: 1204 MGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHT 1263
            +G+P   V WF +G  +   SR           L+I   T  D G Y   A + LG+   
Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236

Query: 1264 SAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETV 1323
            S  + V             +A+          RR  +V+        PQ S+ + N+  V
Sbjct: 4237 SCTLDV-------------KAVRP--------RRGNEVQAC-----KPQTSK-MANVTAV 4269

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD--YVALDLLSVYPEDSG 1381
            EG  V L+ R+   G     VEWF   + I  G R++ A   D    +L +  V  EDSG
Sbjct: 4270 EGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSG 4327

Query: 1382 VYTCQATNQLGEAVTSCALRVIAK 1405
             Y   A+N LGEA T   L V  K
Sbjct: 4328 SYRAVASNNLGEATTLAELTVKGK 4351



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 54/191 (28%), Positives = 81/191 (42%), Gaps = 32/191 (16%)

Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330
            +P   + ++ +G  L   +R  +        L+I    P+DAG Y  +A + LG C  + 
Sbjct: 4179 NPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSC 4238

Query: 2331 SMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQE 2390
            ++ V A         RP    +  E+++ +P                 T  + N+  + E
Sbjct: 4239 TLDVKAV--------RPR---RGNEVQACKPQ----------------TSKMANVTAV-E 4270

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI--TKTHDFGYVSMTISHVRDEDEGV 2448
            G     D R+   G P   VEWFR E+ I D  R    +  D G  S+ IS V+ ED G 
Sbjct: 4271 GWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGS 4328

Query: 2449 YMCRASNLLGE 2459
            Y   ASN LGE
Sbjct: 4329 YRAVASNNLGE 4339



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 4/123 (3%)

Query: 629  EEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI 688
            EED  +  P F++ L   T  EG     E  +E  G P  K+EW KN + ++      S 
Sbjct: 4747 EED--WSAPSFVIELTPTTVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSY 4802

Query: 689  FRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ 748
            F    I L +    ++D+G Y C  ++  G A + A L V    T    ++    +  ++
Sbjct: 4803 FDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAVE 4862

Query: 749  QLE 751
              E
Sbjct: 4863 GTE 4865



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 2/97 (2%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP  T  +K  +V E +   F   +   G PK  + W ++G PI+A  R+    D    
Sbjct: 183  KAPTVTSELKPDKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFDGTTS 240

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             L +K V  +D GTY     N+LG   +++ L V  K
Sbjct: 241  TLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPK 277



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+ IT ++D    VE ++A F        +P+  +EWF     +  G R+    +  I  
Sbjct: 826  PEVITSMRDCD-CVEEETASFHCEFSGKPEPE--IEWFCGPNPIVPGGRFHVTEEGNIQS 882

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
            L I     E++G Y+CVA+N  G+ +T+A LK   K
Sbjct: 883  LAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 67/326 (20%), Positives = 117/326 (35%), Gaps = 15/326 (4%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMR-YNEQTGDVS 130
            P FE          G +      +RG P P + W +    L       ++ Y +  G   
Sbjct: 922  PEFEDWKDTIDALDGQDVNISTWVRGKPKPEIVWLKDGEELRNTMHVQIKCYGDLHG--- 978

Query: 131  LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
            L++ ++ P D G YTC A+N  G     V I  E                 +  T     
Sbjct: 979  LVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEALQKKGDTPTFMSKLEPIEITEGDDF 1038

Query: 191  YGTQGYTTEQSRQTQ----KVAYTNGTDHSSTDDFKVDTFEYRLLREVSF-RESITKRYV 245
              +   T     + Q    +V         ++ D  V       ++E     + + K  V
Sbjct: 1039 QLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL---TVKEAELDDDGVYKCVV 1095

Query: 246  GESDVQISTEIDRS-LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
              +   +S++ D + L     P++ QK  + +  EG  A F V++   P+P + W+    
Sbjct: 1096 TNNFGSVSSKADVTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPEIEWYLGAT 1155

Query: 305  RLINSNKHEIITTHNHTT--LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
            ++ +  + +I T   + +  L + + +  D+G     A N  G  V    L VE    + 
Sbjct: 1156 KITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKNVAP 1215

Query: 363  VQDQRSQYITDTQQRETEERIEISEK 388
                R   +   + RE     EIS K
Sbjct: 1216 SFHGRQGRLRVKEGREASVYFEISGK 1241



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 36/149 (24%), Positives = 70/149 (46%), Gaps = 9/149 (6%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P F+++L  P +++EG      C +   P P   V+W+ +  +++   R++ S D   +A
Sbjct: 1021 PTFMSKLE-PIEITEGDDFQLSCNVTGRPQPE--VQWFRDEVLIKPSRRFKASYDGNVSA 1077

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSR 1963
            L +     +D G Y C   NN G   S   + V  K   +R    +  ++ ++ +E   +
Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH--LRPEVLQK-MDDVRTVE-GGK 1133

Query: 1964 YKRAVQDDSFVVEKPQFGKPIKNAEVTEG 1992
               AV+ D+F   KP+    +   ++T+G
Sbjct: 1134 ANFAVKIDAF--PKPEIEWYLGATKITDG 1160



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 57/254 (22%), Positives = 99/254 (38%), Gaps = 40/254 (15%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYV 1768
            P     MKD    E   A F+ ++     PK  VEW      I    R  LT   + G  
Sbjct: 1704 PEILETMKDAEGIETGKAKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDEEDGTY 1761

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
            ++ +  +  ED GTY   A N++G+    + L V+ K    +  + E      ++ E   
Sbjct: 1762 SVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEKL---IAPEFEG-----RETEVPF 1813

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
            R + + D+EV+ N        +NG                +P PD    V WY + ++L 
Sbjct: 1814 RAKEKSDLEVSYN--------ING----------------KPSPD----VSWYRDDRLLL 1845

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
             G ++            +  V   D+G Y C+A N +G A  +  + ++  ++       
Sbjct: 1846 DGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVGSATRNFNVEIEVPKARDEAPSF 1905

Query: 1949 ESALEKIQYLEDDS 1962
             + L+ I   E ++
Sbjct: 1906 TTTLKPIDVTEGEN 1919



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 5/98 (5%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY--DFGY 2034
            KPQ  K + N    EG  V L+  +T    P   VEW+     +  G R+KT    D G 
Sbjct: 4257 KPQTSK-MANVTAVEGWKVQLDTRMTGY--PVPIVEWFRGEEKITDGGRYKTARMEDEGL 4313

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             +L I     ED+G+Y   A+N +GEA T + + V  K
Sbjct: 4314 YSLIISDVQLEDSGSYRAVASNNLGEATTLAELTVKGK 4351



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L      EG++   E  VE +  P  K+EWF N+KP+      +S  D   + L +
Sbjct: 4755 FVIELTPTTVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIV 4812

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
              T  ED+G+Y C   N  G+A++   L
Sbjct: 4813 RRTTLEDAGLYRCTILNDLGTASSMADL 4840



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 2/108 (1%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F+  L    A EG  + F  ++   G P  +IEW ++G S+E+  R T+ +   + +L
Sbjct: 5249 PAFLKQLLPQNAREGDVVKFSCKV--TGYPEPEIEWTRDGVSMESDERVTTWYDGEHSTL 5306

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
             + + N  DSG Y C   + +G A + A L V  +    R S + + L
Sbjct: 5307 SIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKTQRPRLSDNMKEL 5354



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 100/410 (24%), Positives = 163/410 (39%), Gaps = 75/410 (18%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P     +K  +V EG        +T    P   + WY +G+P++   R K ++D      
Sbjct: 185  PTVTSELKPDKVQEGEQYKFTCAVTGKPKPV--ISWYKDGQPIKADRRVKDSFD------ 236

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLD-TLDEQRLKKIQELEKYER 2096
                     T T + K             VK D K    ++ T D   +    +LE    
Sbjct: 237  -------GTTSTLLIK------------DVKQDDKGTYKVEITNDLGSISSTADLEV--T 275

Query: 2097 PKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156
            PKP        +P  +  + ++E++ EG  A FE + +    P    +WFH+ +KI    
Sbjct: 276  PKPA-------KPEVVRKMENVESV-EGSDAFFEVKFKGYPIPKR--EWFHDSKKIEPSS 325

Query: 2157 RYR-TTHDFGYVA-LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
            R++ TT D    + L I     +DSG Y C A+N+ GE      LKV   +N     +  
Sbjct: 326  RFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV---KNKPFAPEFA 382

Query: 2215 NG-LEKIRQLEAQGHSTRIEV---EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVH 2270
            +G LE I   E Q  + R+ V    +P+++  +  T+L  T  +    T        P  
Sbjct: 383  DGDLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKA 442

Query: 2271 DPNLRIEFY-HNGKALQSAAR-FHIT---------FDFGYVSLDIQ---------HCVPE 2310
              N   +++      L S  R F +T          + G + L ++         +   +
Sbjct: 443  STNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLD 502

Query: 2311 DAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360
            DAGEY VK  N +G  TS   + V  K  +     +PE L K+ ++ + E
Sbjct: 503  DAGEYKVKVTNEVGSVTSLADINV-QKAKV-----KPEFLRKVEDVTALE 546



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 41/152 (26%), Positives = 72/152 (47%), Gaps = 11/152 (7%)

Query: 1280 QNEQAIEQIQLLEDAARRTKQVREDITVMQA-PQFSRALHNIETVEGTNVHLECRLQPVG 1338
            Q+++   ++++  D    +     ++T   A P+  R + N+E+VEG++   E + +  G
Sbjct: 249  QDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFK--G 306

Query: 1339 DQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL--SVYPEDSGVYTCQATNQLGEAVT 1396
                + EWF + K I+   RF+   +       L+   +  +DSG Y C A+N+ GE   
Sbjct: 307  YPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGE--- 363

Query: 1397 SCALRVIAK-KDLILESQHPSG-LEKIQYLED 1426
             C LR   K K+     +   G LE I+  ED
Sbjct: 364  -CNLRADLKVKNKPFAPEFADGDLEPIEVKED 394



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 90/388 (23%), Positives = 157/388 (40%), Gaps = 30/388 (7%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFFNFG 965
            KPE    +++  S+ EG  A FE + +  G    + EW  D + +E SSR  ITT     
Sbjct: 280  KPEVVRKMENVESV-EGSDAFFEVKFK--GYPIPKREWFHDSKKIEPSSRFKITTDDTEQ 336

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLED 1025
              +L I  + + D+G Y C A N  G+    A+L +  K    A     G LE I+  ED
Sbjct: 337  TSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKVKNKP--FAPEFADGDLEPIEVKED 394

Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQ 1085
             +   + T   V    KP       GT ++ + +    +A  +              G+ 
Sbjct: 395  QAVNVRLT---VTGNPKPEVTWYKDGT-QLHDTKKLKLKATGDVHELSIPKASTNDEGQY 450

Query: 1086 ITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSS 1145
               A+     +  G        V     GV  V+    +G   L        + S++T+ 
Sbjct: 451  FCEAS-----NPLGSPKRTF-KVTVVPKGVAPVI---ESGLMPLQVRKETGAKWSVNTTL 501

Query: 1146 IHRGLYEKTRHIEESKFVEPMYQIE-EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPM 1204
               G Y K +   E   V  +  I  + +K KP F++ + +   + E + +  E  ++  
Sbjct: 502  DDAGEY-KVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQ-- 557

Query: 1205 GDPTMRVEWFHNGRSVTVGSRF--KTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAH 1262
            G P   VEW+     +  G RF      +    +L I  A + D+G Y   A N  G   
Sbjct: 558  GYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGK-- 615

Query: 1263 TSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
            T+A++  ++ ++ V   + ++ ++ I++
Sbjct: 616  TTALLN-LDVNEKVVQPEFDKEVKPIEV 642



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 52/244 (21%), Positives = 94/244 (38%), Gaps = 27/244 (11%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576
            P E+ E Q  +   R+   G+P     WY +G +L    + +         L I     N
Sbjct: 388  PIEVKEDQAVN--VRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTN 445

Query: 2577 DAGLYMCKAINRAGXXXXXXXXXXX--XXXXIIDQAMRP--------ESWE-QIQLKEAA 2625
            D G Y C+A N  G                 +I+  + P          W     L +A 
Sbjct: 446  DEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAG 505

Query: 2626 MNKVP--------EMFVDTGVQQAPIFTTHLKSYDKL--VEGQHVYLEAQVEPRTDPNLK 2675
              KV             D  VQ+A +    L+  + +  +E + V+ E  ++    P   
Sbjct: 506  EYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPI-- 563

Query: 2676 IEWFKNGVTLTTGAR--LKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733
            +EW++    +  G R  +  + +  + +L I+  R +DSG Y C A+N  G+  +  ++ 
Sbjct: 564  VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLD 623

Query: 2734 IEDR 2737
            + ++
Sbjct: 624  VNEK 627



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+  L  P  ++EG +  L C +   G P   V+WF +   +    RFK  YD    A
Sbjct: 1021 PTFMSKLE-PIEITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 1077

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            L +  A   D G Y     N+ GS  + A V V+++
Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 3/100 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            +++AP+F + L+    + EG +V    +V     P   +EW+++   L    R K  FD 
Sbjct: 2188 LKEAPVFVSKLRPLF-VTEGDNVSWMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDG 2244

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             + +L ++     D G+Y C  TN  G A S+A ++++ +
Sbjct: 2245 RVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKK 2284



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 2/77 (2%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  +I+W KNG  + +  RL++ +D  +  LSI  + +DD+G Y C A+N  G   S+A+
Sbjct: 2962 PKPQIKWTKNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAA 3021

Query: 2732 IKIEDRHW--LLGESLH 2746
            + +  R+   L+   LH
Sbjct: 3022 LTVSRRNMRPLITHKLH 3038



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 89/382 (23%), Positives = 140/382 (36%), Gaps = 61/382 (15%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK--TTYDFGY 2034
            +P     + + +  EG     +  +T    PT  VEW+     + +G R++  +  + G 
Sbjct: 3030 RPLITHKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEEQGK 3087

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094
             +L +    A+D G Y C A N  G+A T + + V A+   +    DE+           
Sbjct: 3088 HSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIARD--FGPEFDEE----------- 3134

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
            E PKP+                    + EG+ A     V     P   ++WF +G+ +  
Sbjct: 3135 ESPKPV-------------------IVNEGEEAQMMVSVR--GRPKAVVEWFKDGKFLYD 3173

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
              R           L I +   ED G+Y C A++  G +  T  L V   +        P
Sbjct: 3174 SRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRTFDLSVKVPKPKD-KWSLP 3232

Query: 2215 NGLEKIRQLEA-QGHSTRIEVE---EP-------KISPP-----RFVTELRGTTHVFE-G 2257
                K+R LE  +G  T+  V    EP       K   P     RF T   G   +    
Sbjct: 3233 AFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFR 3292

Query: 2258 KTAHFEC-----QVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDA 2312
            KT  FEC     +      P   +E++     L    R+ +       +L I +   ED 
Sbjct: 3293 KTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDT 3352

Query: 2313 GEYSVKAINALGHCTSAISMTV 2334
            G Y + A N  G   S + +TV
Sbjct: 3353 GPYKIIATNEHGSTGSVVDLTV 3374



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F + +    V E ++   E  +   G P  +VEW +N  P++  + + +  D   + 
Sbjct: 4752 APSFVIELTPTTVTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIR 4809

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            L ++    ED+G Y C  +N+LG A + + L V
Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 4/98 (4%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS-IFNFGY 827
            +P+    L+ + E  EG  A F+  +T    P  RV+WY+    IT  +R +S + + G 
Sbjct: 5639 KPEINEKLKKI-EAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGM 5695

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
             SL I  +R ED G Y   AVN+ GE  S   + V  +
Sbjct: 5696 ASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 3/99 (3%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            ++ G  P F++ L  +E + EGD     C V     P   + WF +   I+   R++ ++
Sbjct: 1015 QKKGDTPTFMSKLEPIE-ITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFKASY 1071

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            D    AL +     +D G Y C  TN  G   +   + V
Sbjct: 1072 DGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV 1110



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 5/87 (5%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFG 2432
            RP+ T  L ++    EG+ A FD  +   G P+  VEWF+    I +  R  +    + G
Sbjct: 3030 RPLITHKLHDM-KAYEGKEARFDIEV--TGHPSPTVEWFKGPSGISEGRRYQLMSNEEQG 3086

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459
              S+ +S +  +D+G+Y C A NL G+
Sbjct: 3087 KHSLIVSDLNADDDGIYKCVAQNLAGK 3113



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F  P++  I I EG    F   +   G     VEW +D RPV    R+ T+ +   V 
Sbjct: 5544 PAFTAPLQ-HIDILEGDTTRFIGEIT--GVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L ++   + DAG + C   N +G   +SA+L +
Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 21/68 (30%), Positives = 39/68 (57%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  +IEWF     +  G R   T +  + +L+I+ L+ +D+G Y C A+N  G+  + A 
Sbjct: 853  PEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAE 912

Query: 2732 IKIEDRHW 2739
            +K+ ++H+
Sbjct: 913  LKVNEKHF 920



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 60/229 (26%), Positives = 90/229 (39%), Gaps = 39/229 (17%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            KPE    +KD   + EG  A F  +L   G  +  +EW      +    R     +    
Sbjct: 1410 KPEVLEKMKDVKGV-EGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGRYKFSRDDQKY 1466

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
            +LTIK + + D G Y C A N  G+ T  A L        + E  +    E+ Q+LE   
Sbjct: 1467 SLTIKDLNLQDIGTYKCIASNEAGKVTQRAELE-------VKERDYAPIFEEKQFLEPL- 1518

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT 1087
                    E+++ Q      P++         S H   R +P      TV W+ NGK++ 
Sbjct: 1519 --------EIQVRQ------PVE--------VSYHVRGRPKP------TVTWWKNGKELR 1550

Query: 1088 SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
                ++      Y  L I     ED+G Y  +ARN  G A+    + VE
Sbjct: 1551 DGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVE 1599



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 929  FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
            FE   +  G      EWLKD +PV+    +++ F+     L  K V + D G YT    N
Sbjct: 1625 FELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKN 1684

Query: 989  AIGQATTSANLTIV---TKKDIIAESQHPGGLE 1018
            A G   +SANL IV   +K +I+   +   G+E
Sbjct: 1685 AHGSTYSSANLDIVKSKSKPEILETMKDAEGIE 1717



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 14/162 (8%)

Query: 2100 IEEEQPGQR---PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGH 2156
            +E E P  R   P F T L  ++ + EG+   F CRV    +P +T  W+ N  +I    
Sbjct: 1891 VEIEVPKARDEAPSFTTTLKPID-VTEGENHTFICRVHARPEPSVT--WYRNKNEIVPDG 1947

Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNG 2216
            R RTT D     L +     +D+G Y C A+N +G+A   CT ++  ++  +     P  
Sbjct: 1948 RSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAF--CTAEMTVNKREV----KPVI 2001

Query: 2217 LEKIRQLE-AQGHSTRIEVEEPKISPPRFVTELRGTTHVFEG 2257
             E  +  E ++G +  IEV+   +  P  V    G+  V +G
Sbjct: 2002 KEVSKTFEVSEGGTASIEVKVSGVPVPT-VEWYHGSNRVLDG 2042



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 4/95 (4%)

Query: 2366 EIPEPVTR-QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR 2424
            EI  P  R + P FT  L+ ID + EG+   F CR+    +P+  V W+RN+  I    R
Sbjct: 1892 EIEVPKARDEAPSFTTTLKPID-VTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGR 1948

Query: 2425 ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
               T D     + +  ++ +D G Y C ASN +G+
Sbjct: 1949 SRTTFDGETYKLILQDIKIKDAGQYECIASNPIGK 1983



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 45/155 (29%), Positives = 71/155 (45%), Gaps = 13/155 (8%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G+ P F   L  +  ++E D +   C V     P   I W  NG+ + +  R RT +D G
Sbjct: 2932 GEAPSFSLELRPIAAIEEFD-SKLICHVS--GKPKPQIKWTKNGKPVESDGRLRTDYD-G 2987

Query: 2166 YVA-LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
             VA L I     +D+GTY C A+N  G   ++  L V+  RN+      P    K+  ++
Sbjct: 2988 IVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVS-RRNM-----RPLITHKLHDMK 3041

Query: 2225 A-QGHSTRIEVEEPKISPPRFVTELRGTTHVFEGK 2258
            A +G   R ++E     P   V   +G + + EG+
Sbjct: 3042 AYEGKEARFDIEVTG-HPSPTVEWFKGPSGISEGR 3075



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 31/128 (24%), Positives = 60/128 (46%), Gaps = 8/128 (6%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PKF++ + S  V+E +  +  C++  K +P   +EW+++ +L+ +  R R+       +L
Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTL 3744

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949
                V  +D G Y C A N  G   + A I   +       +  PR +++   +  ++ T
Sbjct: 3745 IFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNR------ASITPRIIEKPRDVDAVDGT 3798

Query: 3950 IKKYTSEV 3957
              K+T  V
Sbjct: 3799 DAKFTVRV 3806



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 4/135 (2%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            EK + P F  E+   + V EG    F   V   G P   I W+ +  P ++  R+ T  D
Sbjct: 3977 EKWSSPIFVTELSP-LSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFD 4033

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809
               + L I  I   D G+Y     N+ GSAT++AK++   +      +QL + + G    
Sbjct: 4034 GHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAITQLYRDVEGFDGS 4093

Query: 3810 ELE-RGRISDAPKEE 3823
            E E   ++S  P  E
Sbjct: 4094 ESELTVQVSGVPAAE 4108



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 4/89 (4%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT--LNDFGFIALDIDYIY 3761
            N+   EG  V  D R+   G P   ++WF        G R  T  + D G  +L I  + 
Sbjct: 4265 NVTAVEGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQ 4322

Query: 3762 ARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              D+G Y   A+N  G ATT A++T   K
Sbjct: 4323 LEDSGSYRAVASNNLGEATTLAELTVKGK 4351



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            + E+    P F+  L     + EG +   E ++T    P  +VEW+K+ +P+     + S
Sbjct: 4745 VPEEDWSAPSFVIELTPT-TVTEGESTALEVEIT--GTPLPKVEWFKNDKPVKHDHLVRS 4801

Query: 822  IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             F+   + L +     EDAG Y    +N LG A S A + V
Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 21/69 (30%), Positives = 40/69 (57%)

Query: 933  LEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ 992
            +E  G    +VEW K+ +PV+    + ++F+   + L ++  T+ DAG Y C   N +G 
Sbjct: 4774 VEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGT 4833

Query: 993  ATTSANLTI 1001
            A++ A+L++
Sbjct: 4834 ASSMADLSV 4842



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 3/93 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F  PL+  + I+EG +  F   +         VEWY + + +T  +R++TY D   V 
Sbjct: 5544 PAFTAPLQHID-ILEGDTTRFIGEITGVP--VPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            L +      D+GV+  V RN  G    SAS+ V
Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 92/392 (23%), Positives = 154/392 (39%), Gaps = 53/392 (13%)

Query: 3295 VEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIVILDILYCYEENSG 3353
            VE   A F+  +     P   VEW+    K+    +++   D  G   L I    ++++G
Sbjct: 3    VESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAG 60

Query: 3354 EYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVE 3413
             Y+CVATN  G+ S + +L    K+        P+  E   E ++  E   V    T   
Sbjct: 61   AYKCVATNDAGQTSLRGDLSVKEKQIA------PQIKEKEQEPIEVFEGESVNLDLTITG 114

Query: 3414 EEKGKAPVFT--VPLSNIEN--LREGENAHFEA--RLTPTDDPNLKVEWYWNGKSLKAGS 3467
            + K +   +    PL   ++  L+  ++++F +  + TP D    K E     K+ K G+
Sbjct: 115  KPKPEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCE----AKN-KIGT 169

Query: 3468 RFRTFCDFGFVILEISPTYPED-------SGE---YLCRAYNNYGEAVT--------TAS 3509
              R F D    +   +PT   +        GE   + C         ++         A 
Sbjct: 170  SARDF-DVNVKVKGKAPTVTSELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQPIKAD 228

Query: 3510 MKVQ----GKRNIILESQLPKGMEGT--IDKIAALEGYSGTVDT-LTPEAESGNPPEFTT 3562
             +V+    G  + +L   + +  +GT  ++    L   S T D  +TP+      PE   
Sbjct: 229  RRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAK---PEVVR 285

Query: 3563 TPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI--LEIG 3620
               ++   E S A FE +         + EWFH+ K +   SR K   D       L I 
Sbjct: 286  KMENVESVEGSDAFFEVKF--KGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVIS 343

Query: 3621 GVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             +   D+G Y C A+N  GE  +   L+VK +
Sbjct: 344  DLRLDDSGAYQCIASNEAGECNLRADLKVKNK 375



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 33/109 (30%), Positives = 50/109 (45%), Gaps = 4/109 (3%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            +  ++VE+  + P   +T +R    V E +TA F C+     +P   IE++     +   
Sbjct: 814  AAEVKVEDRSLKP-EVITSMRDCDCV-EEETASFHCEFSGKPEPE--IEWFCGPNPIVPG 869

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             RFH+T +    SL I     EDAG Y   A NA G  T+   + V  K
Sbjct: 870  GRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 39/156 (25%), Positives = 66/156 (42%), Gaps = 10/156 (6%)

Query: 3365 RDSTKANLKCTSK-ENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEE----KGKA 3419
            R++    +KC      L+L    P   + G+   +   ++ +  KD ++  E    KG  
Sbjct: 963  RNTMHVQIKCYGDLHGLVLYKVSPE--DAGMYTCRAKNNAGIVSKDVTITVEALQKKGDT 1020

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P F   L  IE + EG++  F+     T  P  +V+W+ +   +K   RF+   D     
Sbjct: 1021 PTFMSKLEPIE-ITEGDD--FQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 1077

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            L +     +D G Y C   NN+G   + A + V  K
Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 64/276 (23%), Positives = 107/276 (38%), Gaps = 42/276 (15%)

Query: 3681 KREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFAT 3740
            +R E+ +++    P     +  + +++    PV     V   G P   + W+ NG+    
Sbjct: 1494 QRAELEVKERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVR--GRPKPTVTWWKNGKELRD 1551

Query: 3741 GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800
            G  V   +   +  L I      DAG Y C A N  GS          A+R  + E Q+ 
Sbjct: 1552 GKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGS----------AER--LFEVQV- 1598

Query: 3801 QGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPK 3860
                 E +K          PKEE      PK  +Q++S  + ES+     C V+   DP 
Sbjct: 1599 -----EGVK----------PKEEA-----PKLTSQLRSARITESDDFELACDVKGTPDPS 1638

Query: 3861 LRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKAT-- 3918
               EW ++ K +       + +D    +L+   V   D G Y     N  G  ++ A   
Sbjct: 1639 Y--EWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLD 1696

Query: 3919 -ISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKY 3953
             +  K  P+I+   +   G++  +A  + +  IK Y
Sbjct: 1697 IVKSKSKPEILETMKDAEGIETGKA--KFDVKIKAY 1730



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 2/73 (2%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL-NMKYVNPEDSGTYTCRAINELGEAV 1795
            +G+P+  V W ++G+ +  ++R T M   G +   N+ +V PED+GTY C A N LG + 
Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSR-TDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSF 2711

Query: 1796 TSSTLFVQSKASL 1808
             S T+ ++   S+
Sbjct: 2712 RSCTIEIKEPKSV 2724



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 25/68 (36%), Positives = 40/68 (58%), Gaps = 2/68 (2%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVA-LDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            P  +++W  NG+PV+   R +T YD G VA L I     +D GTY C A+NA G   +++
Sbjct: 2962 PKPQIKWTKNGKPVESDGRLRTDYD-GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSA 3020

Query: 2066 SVKVDAKS 2073
            ++ V  ++
Sbjct: 3021 ALTVSRRN 3028



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 7/121 (5%)

Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAVNQA----PRFITQLNGPTKLSEGQSAHYECRIEP 1870
            +S L K + +       +  DV+  V       P+F++ LN    + EG SA   C++  
Sbjct: 3654 DSGLYKCEGVSTLGTSSKTFDVKAGVPDGSRVTPKFLSHLNS-LDVDEGDSAKLTCKMFG 3712

Query: 1871 YPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
             P+P   VEW+ + +++ +  R R+S       L   TV  +D G Y C A N  G   S
Sbjct: 3713 KPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSS 3770

Query: 1931 S 1931
            S
Sbjct: 3771 S 3771



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 53/206 (25%), Positives = 85/206 (41%), Gaps = 30/206 (14%)

Query: 2000 TLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            T   + +P   V W+ +G  + +  R           L+I     +D GTY+C+A + +G
Sbjct: 4173 TFMVLGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLG 4232

Query: 2060 EAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLE 2119
                + ++ V A        +  +R  ++Q        KP   +        +TA+    
Sbjct: 4233 TCFRSCTLDVKA--------VRPRRGNEVQAC------KPQTSKMAN-----VTAV---- 4269

Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH--DFGYVALDILYTYAE 2177
               EG +   + R+     P   ++WF   +KI  G RY+T    D G  +L I     E
Sbjct: 4270 ---EGWKVQLDTRMTGYPVP--IVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLE 4324

Query: 2178 DSGTYMCKATNKLGEAVNTCTLKVAG 2203
            DSG+Y   A+N LGEA     L V G
Sbjct: 4325 DSGSYRAVASNNLGEATTLAELTVKG 4350



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 10/133 (7%)

Query: 2103 EQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH 2162
            E+    P F+  LT    + EG+    E  VE    P   ++WF N + ++  H  R+  
Sbjct: 4747 EEDWSAPSFVIELTPT-TVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSYF 4803

Query: 2163 DFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQ 2222
            D   + L +  T  ED+G Y C   N LG A +   L V  +R +      P   EK+  
Sbjct: 4804 DGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV--NRAL----TKPEVAEKMTD 4857

Query: 2223 LEA-QGHSTRIEV 2234
            ++A +G   R+EV
Sbjct: 4858 IDAVEGTEVRLEV 4870



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGE 1916
            EG  A ++  +  +P P  RV+WY     +   +RY  T    G A+L I  +  ED G 
Sbjct: 5653 EGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGL 5710

Query: 1917 YTCKAINNLGQAVSSIRLNVQSK 1939
            Y C A+N  G+  S + L+V  K
Sbjct: 5711 YGCVAVNEYGETTSIVDLHVGEK 5733



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G+ P   + L   + ++EG++  F C V     P   I W+ +GQ I+A  R + + D  
Sbjct: 182  GKAPTVTSELKP-DKVQEGEQYKFTCAVT--GKPKPVISWYKDGQPIKADRRVKDSFDGT 238

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               L I     +D GTY  + TN LG   +T  L+V
Sbjct: 239  TSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEV 274



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 79/341 (23%), Positives = 124/341 (36%), Gaps = 57/341 (16%)

Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330
            +P   + +Y +G  L    +  +        L I      D G+Y  +A N LG      
Sbjct: 406  NPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTF 465

Query: 2331 SMTVTAKG--SIISESQRPEGLEKIR--------ELESAEPFKRPEIPE--PVTRQRPVF 2378
             +TV  KG   +I     P  + K           L+ A  +K     E   VT    + 
Sbjct: 466  KVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVTSLADIN 525

Query: 2379 TQP-------LQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT--KTH 2429
             Q        L+ ++++   +T      +   G P   VEW+R    I+D  R T  ++ 
Sbjct: 526  VQKAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESE 585

Query: 2430 DFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQK 2489
            +    S+ I   R ED G Y C ASN  G+              + L+          +K
Sbjct: 586  ENDMYSLVIDEARTEDSGPYKCVASNDAGK----------TTALLNLDVN--------EK 627

Query: 2490 LEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGV 2549
            + QP          EF+K +       P E+  G+ A     +   G P  +  WY + V
Sbjct: 628  VVQP----------EFDKEV------KPIEVKHGEEATTSLEI--KGKPKPKVTWYKDLV 669

Query: 2550 ELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             L      +        TL+I +   +D G Y C+A N+AG
Sbjct: 670  PLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAG 710



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP F  +L  P    E   +   C +   P P  +++W  NGK ++S  R RT  D   
Sbjct: 2933 EAPSFSLELR-PIAAIEEFDSKLICHVSGKPKP--QIKWTKNGKPVESDGRLRTDYDGIV 2989

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            A L I  V  +D+G Y C A N  G   SS  L V  +
Sbjct: 2990 AYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 3/124 (2%)

Query: 3531 TIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMR 3590
            T D  +A   ++  V  + P+ E  + P F T  S L ++E     F   +  V   S  
Sbjct: 3956 TNDLGSAYRIFNLNVTAIAPK-EKWSSPIFVTELSPLSVTEGDYTKFVAHVSGVPLPS-- 4012

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            ++W+ +  P+ +  R++T  D   V L IG +   D G Y     N  G AT S KL V+
Sbjct: 4013 IQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVR 4072

Query: 3651 GRQG 3654
               G
Sbjct: 4073 EEYG 4076



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 37/151 (24%), Positives = 70/151 (46%), Gaps = 8/151 (5%)

Query: 3366 DSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRK--DTSVEE--EKGKAPV 3421
            DS + NL+   +   ++        + G+ K +T  +     +  D  +E+  +   AP 
Sbjct: 4398 DSRRVNLRSVGERYYVVVPSASFE-DSGIYKCETTSEKETTSQLFDIHIEDVCKSALAPG 4456

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            F   L +++ + E E+A F   ++ +  P  +++W+ N + +   SR  T  D     L 
Sbjct: 4457 FKSALRSLD-VTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPVHKLA 4513

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            I+    +D+G Y C A N+ G A +TA + V
Sbjct: 4514 ITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 27/187 (14%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXX 2463
            G+P  +V W+++  L+ D++R+          + I  +  ED G YMC A + LG+    
Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031

Query: 2464 XXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523
                        L+ Q       + K E  H         +  KP+ T+ +   ++  EG
Sbjct: 5032 CI----------LDVQ------AVPKEEVDH--------GQIVKPVITRKIR-DAQGEEG 5066

Query: 2524 QHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583
             +  +E  V     P    EWY   ++L  G +++ +   G  +L I  V  +D G Y  
Sbjct: 5067 SNIRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKV 5124

Query: 2584 KAINRAG 2590
             A N+AG
Sbjct: 5125 VATNQAG 5131



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 2/74 (2%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845
            +EG NI FE +V+    P   +EW+  +  L  G +Y+ +      SL IT   ++D+G 
Sbjct: 5064 EEGSNIRFEIHVKSHPPP--HVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGS 5121

Query: 2846 YTCKATNSKGSATT 2859
            Y   ATN  GS+T+
Sbjct: 5122 YKVVATNQAGSSTS 5135



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 3/81 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P  +++W++    +T   R  ST    G+ +L+I  +R +D G+Y C A N  GE  S  
Sbjct: 5667 PPPRVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIV 5726

Query: 2731 SIKIEDRHWLLGESLHPDSLD 2751
             + + ++H+  G     + LD
Sbjct: 5727 DLHVGEKHY--GPEFAEEELD 5745



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 33/99 (33%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 4106 KARCPPVFVSL-PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM 4164
            K + P V   L PD V  +EGE  +F C VTG PKP + W  +G  I    R K ++DG 
Sbjct: 181  KGKAPTVTSELKPDKV--QEGEQYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDGT 238

Query: 4165 YH-FDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
                 I   +Q D G  +V              L+V P+
Sbjct: 239  TSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPK 277



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 9/159 (5%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P   +++K   V+E E  +F C V  K  PK  I WY++G+ + +  R +  +D    +L
Sbjct: 185  PTVTSELKPDKVQEGEQYKFTCAVTGK--PKPVISWYKDGQPIKADRRVKDSFDGTTSTL 242

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEAT 3949
             I  V  +D G Y     ND G   + A +     P    + +V R M+  E++   +A 
Sbjct: 243  LIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKP---AKPEVVRKMENVESVEGSDAF 299

Query: 3950 IK-KYTSEVYLTEDDLYDVDKKQPP---RFVTQIQSQTS 3984
             + K+        +  +D  K +P    +  T    QTS
Sbjct: 300  FEVKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTS 338



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 59/226 (26%), Positives = 89/226 (39%), Gaps = 38/226 (16%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+ +  +K V  +EG +  F  ++   G P+  IEW      I    R+         SL
Sbjct: 1411 PEVLEKMKDVKGVEGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGRYKFSRDDQKYSL 1468

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
             +  LN+QD G Y C A +  G         VT RA +E   +            DY+  
Sbjct: 1469 TIKDLNLQDIGTYKCIASNEAG--------KVTQRAELEVKER------------DYAPI 1508

Query: 757  QHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
                  EE+     QF+ PL    E+Q  +       +     PT  V W+K+G+ +   
Sbjct: 1509 -----FEEK-----QFLEPL----EIQVRQPVEVSYHVRGRPKPT--VTWWKNGKELRDG 1552

Query: 817  SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
              +       Y +L I+    EDAGSY   A N +G A     ++V
Sbjct: 1553 KHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQV 1598



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/69 (33%), Positives = 37/69 (53%)

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
            G  T  + W+ +G+P+    R       +   L +L++ PED+G YTC+A N++G A  S
Sbjct: 2861 GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920

Query: 1398 CALRVIAKK 1406
              + V A K
Sbjct: 2921 FEVDVTAPK 2929



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 2646 THLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR--LKSTFDFGLVTLS 2703
            TH     K  EG+    + +V     P   +EWFK    ++ G R  L S  + G  +L 
Sbjct: 3034 THKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEEQGKHSLI 3091

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            ++ L  DD GIY C A NL G+A + A + +
Sbjct: 3092 VSDLNADDDGIYKCVAQNLAGKASTRAMLDV 3122



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F   L     + EG+   LE ++     P  K+EWFKN   +     ++S FD  ++
Sbjct: 4752 APSFVIELTP-TTVTEGESTALEVEITGTPLP--KVEWFKNDKPVKHDHLVRSYFDGKVI 4808

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             L +     +D+G+Y C   N LG A S A + +
Sbjct: 4809 RLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 5/107 (4%)

Query: 1835 DVEVA--VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            DVEV   V  AP    QL     ++EG      C++  YP+P +  EW  N ++L    R
Sbjct: 1304 DVEVKQEVMIAPEIRQQLQAED-VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDR 1360

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            ++T  D     L I  V   D+  Y     N+ G+  SS +L V  K
Sbjct: 1361 FKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK 1407



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 2/84 (2%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V+EG +  L C++    +PT+  EW  N   ++   RFKT +D     L I + T AD  
Sbjct: 1326 VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAV 1383

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIER 1272
             Y V   N  G   +SA ++VI +
Sbjct: 1384 PYKVVVRNDAGEVSSSAKLKVIRK 1407



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 28/77 (36%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EGD   F  NV+ S  P+  IEW++    +  G RYK + D    SL I     +D G Y
Sbjct: 1424 EGDEATF--NVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTY 1481

Query: 2847 TCKATNSKGSATTSGSL 2863
             C A+N  G  T    L
Sbjct: 1482 KCIASNEAGKVTQRAEL 1498



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 7/159 (4%)

Query: 3083 EWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVD 3142
            EW  + K ++    + + +      L     + +D G+Y+    N  G    S  L+ V 
Sbjct: 1640 EWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIV- 1698

Query: 3143 KSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS 3202
            KSK  KP     +++ EG++ G+ A F+  +     P  ++EWYH    +    R     
Sbjct: 1699 KSK-SKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQ 1754

Query: 3203 D--FGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
            D   G   + I   +  D G Y   A+N  G+   RA +
Sbjct: 1755 DEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAEL 1793



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 33/108 (30%), Positives = 53/108 (49%), Gaps = 5/108 (4%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            ++T    K   P F++E++    + E       C V   G P  +I W  NG+P  +  R
Sbjct: 2924 DVTAPKVKGEAPSFSLELRPIAAIEEFDS-KLICHVS--GKPKPQIKWTKNGKPVESDGR 2980

Query: 3744 VHTLNDFGFIA-LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            + T  D G +A L I  +   DAG Y C A+N  G+ +++A +T S +
Sbjct: 2981 LRTDYD-GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 2/123 (1%)

Query: 625  IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
            +  G  D     P+F+  L S+   EG       ++   G P   +EW K+ Q I  + R
Sbjct: 3675 VKAGVPDGSRVTPKFLSHLNSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDR 3732

Query: 685  FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
              S       +L   ++NIQD G Y C A +  G   + AV+ V   +   R  + P  +
Sbjct: 3733 VRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNRASITPRIIEKPRDV 3792

Query: 745  QYI 747
              +
Sbjct: 3793 DAV 3795



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 3/80 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F   L+++D + E ++A F C +   G P  +++WF N++ +   SRI  + D     
Sbjct: 4455 PGFKSALRSLD-VTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511

Query: 2436 MTISHVRDEDEGVYMCRASN 2455
            + I+    +D GVY C A N
Sbjct: 4512 LAITKATLQDTGVYKCLAVN 4531



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT PLQ+ID I EG T  F   +   G P   VEW+R+++ +    R+    D   V 
Sbjct: 5544 PAFTAPLQHID-ILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + +      D GV+ C   N LG
Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLG 5623



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 87/368 (23%), Positives = 140/368 (38%), Gaps = 46/368 (12%)

Query: 3591 VEWFHNGKPLLTGSRVKTI-NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            VEW+     + +  + K + +D G   L I  + + DAG Y C ATN  G+ ++   L V
Sbjct: 22   VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRGDLSV 81

Query: 3650 KGRQGIILEPQLPSHFKSGTESIQ----KLEETLH---KREEITIEDEKPNPPRFTVEIK 3702
            K +Q   + PQ+    +   E  +     L+ T+    K E +  +D KP     ++++K
Sbjct: 82   KEKQ---IAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSIDLK 138

Query: 3703 DNID-----VPEGGPVH---FDCRVE-PVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
               D     +P+  P     + C  +  +G          + R F    +V         
Sbjct: 139  STDDSYFLSIPKATPNDSGKYKCEAKNKIGT---------SARDFDVNVKVKGKAPTVTS 189

Query: 3754 ALDIDYIYARDAGEYTCRATNK------WGS------ATTTAKITCSAKRDIVLESQLPQ 3801
             L  D +   +  ++TC  T K      W        A    K +       +L   + Q
Sbjct: 190  ELKPDKVQEGEQYKFTCAVTGKPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQ 249

Query: 3802 GMSGEKIKEL--ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859
               G    E+  + G IS     E +   P K     K   VE  EG      V+ K  P
Sbjct: 250  DDKGTYKVEITNDLGSISSTADLE-VTPKPAKPEVVRKMENVESVEGSDAFFEVKFKGYP 308

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYD--MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKA 3917
              + EW+ + K +    R++   D      SL I  +  +DSG Y C A N+ GE   +A
Sbjct: 309  IPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGECNLRA 368

Query: 3918 TISCKKLP 3925
             +  K  P
Sbjct: 369  DLKVKNKP 376



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 39/151 (25%), Positives = 61/151 (40%), Gaps = 13/151 (8%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   ++ I + E     F+      G P+  V+W R+ V I+ S R    +D    AL
Sbjct: 1021 PTFMSKLEPIEITEGD--DFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 1078

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQH--ESALQKIQQLEDSS 1828
             +K    +D G Y C   N  G         V SKA + +  +H     LQK+  +    
Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFGS--------VSSKADVTVLKKHLRPEVLQKMDDVRTVE 1130

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
              +    V++     P     L G TK+++G
Sbjct: 1131 GGKANFAVKIDAFPKPEIEWYL-GATKITDG 1160



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 75/331 (22%), Positives = 121/331 (36%), Gaps = 52/331 (15%)

Query: 2272 PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS 2331
            P+  +E+Y     L S  +  +    G   L+I+    +DAG Y  KA N++G  +  I 
Sbjct: 2123 PSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRII 2182

Query: 2332 MTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEG 2391
            + V A                   L+ A  F        V++ RP+F     N+      
Sbjct: 2183 VDVEA-------------------LKEAPVF--------VSKLRPLFVTEGDNVS----- 2210

Query: 2392 QTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMC 2451
                + C++  +  PT  VEW+R+ + +   +R     D    S+ +S    +D+GVY C
Sbjct: 2211 ----WMCKVAGMPRPT--VEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNC 2264

Query: 2452 RASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHE-RRSEEPDREF----- 2505
              +N  G                    +    ++ ++  E   + R S  P  E      
Sbjct: 2265 VITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRN 2324

Query: 2506 ------EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT 2559
                  EK      L  P  + E    +++ RV   G P     WY +G  ++   RF  
Sbjct: 2325 SIKVRNEKFYGDDELKEPVVVQESDAINFKVRV--RGKPVPTIVWYKDGEMVRDVRRFEI 2382

Query: 2560 THDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                   T    S  A DAG Y C+A N+ G
Sbjct: 2383 RSRGDIYTFATYSASAEDAGTYTCEASNKLG 2413



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 55/232 (23%), Positives = 92/232 (39%), Gaps = 39/232 (16%)

Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERR--LIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            VD   T+AP     +K+    EG      R   L+  SD  + +EW+     L+ G ++ 
Sbjct: 2724 VDSTDTRAPGQLIPVKHKFDFEGVPGGKARCDVLVKKSDI-IDIEWFRGTNMLRDGDKYK 2782

Query: 1628 --ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGAL 1685
              ++++   ++L + +   ED+GTY C               +VH+           G  
Sbjct: 2783 ILKSDDGQTLSLIVENVCGEDAGTYRC---------------VVHTPA---------GQT 2818

Query: 1686 PRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVE 1745
                +L    K Q     DE ++Q   F++P         Q           G P   + 
Sbjct: 2819 TIRGELHIKEKQQAPLFLDEKVSQEK-FSLP---------QGQEMNKSFTVTGSPTPHIT 2868

Query: 1746 WLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            W ++G P++ + R+          L +  + PED+GTYTC A N +G A  S
Sbjct: 2869 WYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 5/133 (3%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P FL+ L SL+ + EGD A   C++     P  T++WF + Q I    R R++       
Sbjct: 3687 PKFLSHLNSLD-VDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCT 3743

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGH 2228
            L       +D G Y C ATN+ G   ++  + V          + P  ++ +   +A+  
Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNRASITPRIIEKPRDVDAVDGTDAK-F 3802

Query: 2229 STRIE-VEEPKIS 2240
            + R+E   +PK++
Sbjct: 3803 TVRVEGFPQPKVT 3815



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 2/89 (2%)

Query: 67   GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
            G+   P+  +  ++A+  +G N +FE  ++ +P P V W R    L    KY +  +E  
Sbjct: 5047 GQIVKPVITRKIRDAQGEEGSNIRFEIHVKSHPPPHVEWYRGSIKLAHGPKYQI--SEGD 5104

Query: 127  GDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
            G  SL I  +   D G Y   A NQ G +
Sbjct: 5105 GAYSLTITGVQKDDTGSYKVVATNQAGSS 5133



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L     +EGD + F C V    +P  +IEW  +   + S  R  + +D  + +L I
Sbjct: 5251 FLKQLLPQNAREGDVVKFSCKVTGYPEP--EIEWTRDGVSMESDERVTTWYDGEHSTLSI 5308

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
             +    DSG+Y C   N+ G A++S  L
Sbjct: 5309 HNANHADSGMYKCTLKNNSGWASSSAEL 5336



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 47/210 (22%), Positives = 84/210 (40%), Gaps = 23/210 (10%)

Query: 3996 QLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV-AMNFGWVYPEDSGEYLCRATNLY 4054
            +L   G+P  +V W+ +G  L H  +   +   G V  ++       D G+Y C A+N  
Sbjct: 400  RLTVTGNPKPEVTWYKDGTQL-HDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPL 458

Query: 4055 GMDET--KAVIKTTGKPGIVYDSQLPKHMK-------SIE---------KIREMEASWQV 4096
            G  +   K  +   G   ++    +P  ++       S+          K++       V
Sbjct: 459  GSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSV 518

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            T    +   KA+  P F+   + VT  E E   F   + G+P+P V W      I +G R
Sbjct: 519  TSLADINVQKAKVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGR 578

Query: 4157 YKLT---YDGMYHFDIPKTRQYDTGKIEVI 4183
            + ++    + MY   I + R  D+G  + +
Sbjct: 579  FTISESEENDMYSLVIDEARTEDSGPYKCV 608



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 2/121 (1%)

Query: 2615 SWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNL 2674
            S++ +    A         V T  + AP F    +    + EGQ+      +  R  P+ 
Sbjct: 2068 SYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTIRARPSPD- 2126

Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +EW+K    L +  ++      GL  L I     DD+G Y CKATN +G       + +
Sbjct: 2127 -VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRIIVDV 2185

Query: 2735 E 2735
            E
Sbjct: 2186 E 2186



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 2/99 (2%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165
            K   P   + L     +EE + ++  C V+G PKP++ W  NG  + +  R +  YDG+ 
Sbjct: 2931 KGEAPSFSLELRPIAAIEEFD-SKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIV 2989

Query: 4166 -HFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRH 4203
             +  I +    D G  E I             L V  R+
Sbjct: 2990 AYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRRN 3028



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 35/122 (28%), Positives = 52/122 (42%), Gaps = 4/122 (3%)

Query: 3670 ESIQKLEETLHKRE-EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMR 3728
            E+  KL  T  K + +I   +  P  P F  ++    +  EG  V F C+V   G P   
Sbjct: 5223 EATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLLPQ-NAREGDVVKFSCKV--TGYPEPE 5279

Query: 3729 IDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCS 3788
            I+W  +G    +  RV T  D     L I      D+G Y C   N  G A+++A++   
Sbjct: 5280 IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVG 5339

Query: 3789 AK 3790
             K
Sbjct: 5340 GK 5341



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 634  YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-G 692
            Y  P+    LK + A EGG+  F+  +   G P  +++W +    I   +R++S     G
Sbjct: 5637 YSKPEINEKLKKIEAFEGGEARFDLLV--TGFPPPRVDWYRGTTKITDCNRYSSTLTSDG 5694

Query: 693  YISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
              SL +  +  +D G Y C AV+  G   +   LHV
Sbjct: 5695 MASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHV 5730



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 38/128 (29%), Positives = 58/128 (45%), Gaps = 9/128 (7%)

Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEGQRAH 1596
            ST  I    Q++ G  ++++  D      T  ++     A P     ++NVE  EG  A 
Sbjct: 240  STLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVEGSDAF 299

Query: 1597 FERRL--IPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTC 1652
            FE +    P+     K EW+H++K ++  SRF  T  +     +L I     +DSG Y C
Sbjct: 300  FEVKFKGYPIP----KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQC 355

Query: 1653 RAINALGE 1660
             A N  GE
Sbjct: 356  IASNEAGE 363



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 23/87 (26%), Positives = 40/87 (45%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           +P+ P   +  +N    +G +A FE K +G P P   W      +   +++ +  ++   
Sbjct: 277 KPAKPEVVRKMENVESVEGSDAFFEVKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQ 336

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGE 154
             SL+I  +   D G Y C A N+ GE
Sbjct: 337 TSSLVISDLRLDDSGAYQCIASNEAGE 363



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 34/114 (29%), Positives = 50/114 (43%), Gaps = 5/114 (4%)

Query: 1027 SRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
            S YS    + VK   KP  L  +K    I  G+ A F+ +++        VEWY    +I
Sbjct: 1688 STYSSANLDIVKSKSKPEILETMKDAEGIETGK-AKFDVKIKAYPKAE--VEWYHRSARI 1744

Query: 1087 TSANRIQTYHDF--GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
                R     D   G  ++ I  +R ED G Y +VA N  G+    A +TV+ +
Sbjct: 1745 YDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 36/116 (31%), Positives = 52/116 (44%), Gaps = 8/116 (6%)

Query: 2227 GHSTR---IEVEEPKI--SPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHN 2281
            G +TR   +E+E PK     P F T L+    V EG+   F C+V    +P+  + +Y N
Sbjct: 1883 GSATRNFNVEIEVPKARDEAPSFTTTLK-PIDVTEGENHTFICRVHARPEPS--VTWYRN 1939

Query: 2282 GKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
               +    R   TFD     L +Q    +DAG+Y   A N +G       MTV  +
Sbjct: 1940 KNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 21/92 (22%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 4095 QVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154
            + + + +V  ++    P  +  P  + + EG  +RF  R+ GHP P V W      + +G
Sbjct: 2513 EASSKALVGVNRGTVGPEIIEKPAGLVIVEGNDSRFDVRIRGHPTPEVEWFYGSERLTDG 2572

Query: 4155 SRYKLTYD---GMYHFDIPKTRQYDTGKIEVI 4183
             +Y++  +   G+Y   + K +   TG   ++
Sbjct: 2573 VKYRIESNPEIGLYSLVVSKVQLDQTGHYRIV 2604



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 4/97 (4%)

Query: 1842 QAPRFITQLNGPTKLS--EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            QAP F+ +     K S  +GQ  +    +   P P+  + WY +G+ L    R    +  
Sbjct: 2831 QAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPH--ITWYKDGEPLDDTRRIDIRSRG 2888

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
                L IL +  ED+G YTC+A N +G A  S  ++V
Sbjct: 2889 NVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 33/112 (29%), Positives = 57/112 (50%), Gaps = 8/112 (7%)

Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLT--PTDDPNLKVEWYWNGKSLKAG 3466
            D +  + KG+AP F++ L  I  + E     F+++L    +  P  +++W  NGK +++ 
Sbjct: 2924 DVTAPKVKGEAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESD 2978

Query: 3467 SRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNI 3518
             R RT  D     L I     +D+G Y C A N  G   ++A++ V  +RN+
Sbjct: 2979 GRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTV-SRRNM 3029



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 2/94 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F  +++     E    +  C V  K  PK +I+W +NGK + S  R RT YD     L
Sbjct: 2935 PSFSLELRPIAAIEEFDSKLICHVSGK--PKPQIKWTKNGKPVESDGRLRTDYDGIVAYL 2992

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             I  V  +D+G Y C A N  G   + A ++  +
Sbjct: 2993 SIWQVSHDDAGTYECIASNAAGTVSSSAALTVSR 3026



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFT--SIFRFGYISLDMLS 700
            L  + A EG +  F+  IE  G P+  +EW K    I    R+   S    G  SL +  
Sbjct: 3037 LHDMKAYEGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSD 3094

Query: 701  LNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            LN  D G Y C A +  G A T+A+L V  R
Sbjct: 3095 LNADDDGIYKCVAQNLAGKASTRAMLDVIAR 3125



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            +P+F   +  + V E     F A +   G P   ++W ++  PI +++R+ T  D   V 
Sbjct: 3981 SPIFVTELSPLSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVK 4038

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            L +  +  ED G Y     NE G A +S+ L V+ +
Sbjct: 4039 LLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREE 4074



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 5/102 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F + ++S  V E E   F C V     P  RI+W+ N + +    R  T  D     L
Sbjct: 4455 PGFKSALRSLDVTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPVHKL 4512

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATIS---CKKLPDII 3928
             I     +D+G Y C AVND G   + A ++   C+  P  +
Sbjct: 4513 AITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFV 4554



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 3/94 (3%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P F   L+ L ++ E  +A F  +++    P  R++W+ + +P++  SRI +  +     
Sbjct: 4455 PGFKSALRSL-DVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            L I     +D G Y   AVN  G A STA + V+
Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVS 4545



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 3/95 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP F   L   +   EG  V    +V    +P  +IEW ++GV++ +  R+ + +D   
Sbjct: 5247 KAPAFLKQLLPQNAR-EGDVVKFSCKVTGYPEP--EIEWTRDGVSMESDERVTTWYDGEH 5303

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             TLSI++  + DSG+Y C   N  G A S+A + +
Sbjct: 5304 STLSIHNANHADSGMYKCTLKNNSGWASSSAELVV 5338



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP F+  L +I+ +EG        +   G     VEW+ + +P+   HR R   +   V 
Sbjct: 5543 APAFTAPLQHIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L L      D+GV+ C   N LG   +S +L V
Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 5/87 (5%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            KPE ++      + VEG     E  V+ K  P  K EW+ + K +E  SRFK+T+D    
Sbjct: 280  KPE-VVRKMENVESVEGSDAFFE--VKFKGYPIPKREWFHDSKKIEPSSRFKITTDDTEQ 336

Query: 2970 TLDLV--DVYERDSGIYTCKAYNKRGE 2994
            T  LV  D+   DSG Y C A N+ GE
Sbjct: 337  TSSLVISDLRLDDSGAYQCIASNEAGE 363



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 4/85 (4%)

Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS--INSLRNDDS 2712
            VEG   + E + +    P  K EWF +   +   +R K T D    T S  I+ LR DDS
Sbjct: 293  VEGSDAFFEVKFKGYPIP--KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDS 350

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDR 2737
            G Y C A+N  GE    A +K++++
Sbjct: 351  GAYQCIASNEAGECNLRADLKVKNK 375



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 4/106 (3%)

Query: 1837 EVAVN--QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
            E+ VN  +    I +++   ++SEG +A  E ++   P P   VEWY     +  G R++
Sbjct: 1989 EMTVNKREVKPVIKEVSKTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQ 2046

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             + +  +  L I  V  + +  Y C A NN G+      L +  +E
Sbjct: 2047 VTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITERE 2092



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 3/124 (2%)

Query: 1816 SALQKIQQLEDSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874
            +A  K     ++ R   R D+ +   + AP F         + EGQ+A     I   P P
Sbjct: 2066 AASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRIAVREGQNAITNMTIRARPSP 2125

Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRL 1934
            +  VEWY    +L S  +       G   L+I     +D+G Y CKA N++G     I +
Sbjct: 2126 D--VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRIIV 2183

Query: 1935 NVQS 1938
            +V++
Sbjct: 2184 DVEA 2187



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 27/96 (28%), Positives = 43/96 (44%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            QQAP+F     S +K    Q   +         P   I W+K+G  L    R+       
Sbjct: 2830 QQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRIDIRSRGN 2889

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +  L I +L+ +D+G YTC+A N +G A  +  + +
Sbjct: 2890 VYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P+F   L++++  EG +  L C++   G     VEWF + + I    R R +   +   L
Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTL 3744

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
               +V  +D G Y C ATNQ G   +S  + V
Sbjct: 3745 IFETVNIQDRGAYRCTATNQEGSTSSSAVIVV 3776



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 33/94 (35%), Positives = 42/94 (44%), Gaps = 4/94 (4%)

Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTT--MHDFGYVALN 1771
            T  M ++   E      + R+   G P   VEW R    I    R  T  M D G  +L 
Sbjct: 4260 TSKMANVTAVEGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLI 4317

Query: 1772 MKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            +  V  EDSG+Y   A N LGEA T + L V+ K
Sbjct: 4318 ISDVQLEDSGSYRAVASNNLGEATTLAELTVKGK 4351



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 3/94 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP F + L+S D + E +      +V     P  +I+WF N   ++  +R+ ++ D  + 
Sbjct: 4454 APGFKSALRSLD-VTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPVH 4510

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             L+I      D+G+Y C A N  G A STA + +
Sbjct: 4511 KLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 2/90 (2%)

Query: 4095 QVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154
            Q  P++ V+  +   P +   + DA   EEG   RF   V  HP P V W      + +G
Sbjct: 5037 QAVPKEEVDHGQIVKPVITRKIRDAQG-EEGSNIRFEIHVKSHPPPHVEWYRGSIKLAHG 5095

Query: 4155 SRYKLTY-DGMYHFDIPKTRQYDTGKIEVI 4183
             +Y+++  DG Y   I   ++ DTG  +V+
Sbjct: 5096 PKYQISEGDGAYSLTITGVQKDDTGSYKVV 5125



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 4/104 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT-T 960
            V E   KPE    +K +I   EGG A F+  L   G    RV+W +    +   +R + T
Sbjct: 5633 VNEGYSKPEINEKLK-KIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSST 5689

Query: 961  FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
              + G  +LTI+ +   D G Y C A N  G+ T+  +L +  K
Sbjct: 5690 LTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 5/96 (5%)

Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSIFNFG 826
           +P+ +R ++++ E  EG +A FE +      P  + EW+ D + I  SSR  IT+     
Sbjct: 280 KPEVVRKMENV-ESVEGSDAFFEVKFKGY--PIPKREWFHDSKKIEPSSRFKITTDDTEQ 336

Query: 827 YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             SL I  LR +D+G+Y   A N+ GE    A ++V
Sbjct: 337 TSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKV 372



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 7/112 (6%)

Query: 1832 RREDVEVAV----NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL 1887
            R  D++V V     + P   T++     + +G+     C +   P+P   VEW+ +GK L
Sbjct: 714  RSFDIKVKVAEPQGETPTITTEMTDIQAI-DGEDCKLICHVTGEPNPE--VEWFKDGKPL 770

Query: 1888 QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            ++ HR   S +    AL    +  ED G Y C   N  G   S+  + V+ +
Sbjct: 771  KANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P   T    I+  I+G+     C +    + N +VEWFK+G+P+   HR  P  +   +A
Sbjct: 730  PTITTEMTDIQ-AIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMIA 786

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGT 1527
            L    +  ED G Y C   N+ G+
Sbjct: 787  LSFRPIKLEDMGRYKCVISNVFGS 810



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 3/102 (2%)

Query: 2100 IEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYR 2159
            ++ E    +P  +T++   + ++E + A F C      +P   I+WF     I  G R+ 
Sbjct: 817  VKVEDRSLKPEVITSMRDCDCVEE-ETASFHCEFSGKPEPE--IEWFCGPNPIVPGGRFH 873

Query: 2160 TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             T +    +L I     ED+G Y C A+N  G+      LKV
Sbjct: 874  VTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKV 915



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGY-V 1768
            AP F      +RV E + A     +   G PK  V W ++ V I   +R   ++  G   
Sbjct: 1214 APSFHGRQGRLRVKEGREASVYFEIS--GKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSY 1271

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
               +K   PED GTY C A N++G A  +  + V+ K  + +  +    LQ
Sbjct: 1272 YFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQ 1322



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 58/216 (26%), Positives = 87/216 (40%), Gaps = 37/216 (17%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            +P   + ++++  + EG  A F+ +L   G P+  +EW+     I D  R   + D    
Sbjct: 1410 KPEVLEKMKDVKGV-EGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGRYKFSRDDQKY 1466

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494
            S+TI  +  +D G Y C ASN  G+                  TQ  E    ++  E+ +
Sbjct: 1467 SLTIKDLNLQDIGTYKCIASNEAGKV-----------------TQRAE----LEVKERDY 1505

Query: 2495 ERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMG 2554
                EE  ++F +P+  QV   P E+       Y  R    G P     W+ NG EL+ G
Sbjct: 1506 APIFEE--KQFLEPLEIQV-RQPVEV------SYHVR----GRPKPTVTWWKNGKELRDG 1552

Query: 2555 SRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                      + TL I      DAG Y C A N  G
Sbjct: 1553 KHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVG 1588



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 8/103 (7%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLV--PVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            E P F  +++ +  + E     F+++L+      P  +++W  NGK +    R RT +D 
Sbjct: 2933 EAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDG 2987

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             +  L I     +++G YEC+A+N  G  S+ A L   S+ N+
Sbjct: 2988 IVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAAL-TVSRRNM 3029



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 6/97 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRI--EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI 694
            P F + L+ + A+E     F++++     G P  +I+W KNG+ +E+  R  + +     
Sbjct: 2935 PSFSLELRPIAAIE----EFDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTDYDGIVA 2990

Query: 695  SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
             L +  ++  D+G Y C A +A G   + A L V+ R
Sbjct: 2991 YLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 5/101 (4%)

Query: 767  SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF- 825
            + RP     L D+ +  EG+ A F+ ++T    PT  VEW+K    I+   R   + N  
Sbjct: 3028 NMRPLITHKLHDM-KAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEE 3084

Query: 826  -GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
             G  SL +  L A+D G Y   A N  G+A + A + V AR
Sbjct: 3085 QGKHSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIAR 3125



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 4/87 (4%)

Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK--STFDFGLVTLSINSLRNDDS 2712
            VEG  V  + ++     P+  +EW++  + L    + K   T + GL +L +N +  DD 
Sbjct: 3500 VEGWKVQFQTRITGYPYPH--VEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDI 3557

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHW 2739
            G Y C ATN  G +    ++ ++D+ +
Sbjct: 3558 GTYKCLATNSAGSSACRINLDVKDKQY 3584



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 4/100 (4%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P+F+  L  L ++ EG +A    ++    +PT  VEW+KD + IT + R+ S       +
Sbjct: 3687 PKFLSHLNSL-DVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCT 3743

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVT 869
            L    +  +D G+Y   A N+ G   S+A I V  R+++T
Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVI-VVNRASIT 3782



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 6/101 (5%)

Query: 1171 EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT-- 1228
            E+   KP     ++N   V EG  + L+ R+   G P   VEWF     +T G R+KT  
Sbjct: 4252 EVQACKPQ-TSKMANVTAV-EGWKVQLDTRMT--GYPVPIVEWFRGEEKITDGGRYKTAR 4307

Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
              D G  +L I      D+G Y   A N+LG A T A + V
Sbjct: 4308 MEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELTV 4348



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/64 (40%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 3591 VEWFHNGKPLLTGSRVKT--INDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ 3648
            VEWF   + +  G R KT  + D G   L I  V   D+G Y   A+N  GEAT   +L 
Sbjct: 4288 VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELT 4347

Query: 3649 VKGR 3652
            VKG+
Sbjct: 4348 VKGK 4351



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 35/150 (23%), Positives = 60/150 (40%), Gaps = 3/150 (2%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            +EW+     +    + +     G   L I G +  D+G+Y   ATN+ G +    ++   
Sbjct: 5083 VEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVVVK 5142

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            DK    K    T    I  +  G   +   T+     P   + WY +G  +  S  ++  
Sbjct: 5143 DKPLAPKVAEMTATGPIT-ITRGNQLNLNVTIR--GKPKPSVVWYKDGNKILTSRNVQIR 5199

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            S      L I +T++  +G Y C A +K G
Sbjct: 5200 SCGDVYHLIILFTKSEHAGTYSCEATSKLG 5229



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 4/93 (4%)

Query: 2366 EIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI 2425
            + PE   +  P F + L    N +EG    F C++   G P  ++EW R+   +E   R+
Sbjct: 5240 QAPEAAPKA-PAFLKQLLP-QNAREGDVVKFSCKV--TGYPEPEIEWTRDGVSMESDERV 5295

Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            T  +D  + +++I +    D G+Y C   N  G
Sbjct: 5296 TTWYDGEHSTLSIHNANHADSGMYKCTLKNNSG 5328



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 40/148 (27%), Positives = 66/148 (44%), Gaps = 5/148 (3%)

Query: 1660 EAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV--ITQAPVFTMPM 1717
            E VT+     HS  SI+  +  +  + +   L++ S +   SA+  V   TQ P  +  M
Sbjct: 5293 ERVTTWYDGEHSTLSIHNANHADSGMYKCT-LKNNSGWASSSAELVVGGKTQRPRLSDNM 5351

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            K++       A FE  +     PK ++ W ++ + + + +R T   + G   L +K V  
Sbjct: 5352 KELFATVGGEARFEVTM--KATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQL 5409

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             DSGTY   A N+ G+      L V  K
Sbjct: 5410 SDSGTYKFVASNKAGKTTFLGYLEVMEK 5437



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 5/100 (5%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET-NNFGFVA 1636
            P     LK +E  EG  A F+  L+       +V+WY     +   +R++ T  + G  +
Sbjct: 5640 PEINEKLKKIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMAS 5697

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIY 1676
            L I     ED G Y C A+N  GE  T+ I  +H  +  Y
Sbjct: 5698 LTIRKIRQEDGGLYGCVAVNEYGE--TTSIVDLHVGEKHY 5735



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 1/94 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P F+S  + + + EG+  +  C VTG P+P V W  +   I    R+K +YDG +    +
Sbjct: 1021 PTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTV 1080

Query: 4170 PKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRH 4203
             +    D G  + +             + V+ +H
Sbjct: 1081 KEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH 1114



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 84/362 (23%), Positives = 134/362 (37%), Gaps = 71/362 (19%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S  +++ + K S P  +  ++    +  GK A F+ +++    P   +E+YH    +   
Sbjct: 1692 SANLDIVKSK-SKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDG 1747

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPE 2348
             R+ +T D             E+ G YSV  IN L       +  + A   I   S+R E
Sbjct: 1748 GRYCLTQD-------------EEDGTYSV-TINDL-RLEDCGTYKIVAFNDIGKTSERAE 1792

Query: 2349 GLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTL 2408
                ++E   A  F+  E   P   +     +   NI+                 G P+ 
Sbjct: 1793 --LTVKEKLIAPEFEGRETEVPFRAKEKSDLEVSYNIN-----------------GKPSP 1833

Query: 2409 KVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXX 2468
             V W+R+++L+ D  +            T+ +V   D G Y C A N +G          
Sbjct: 1834 DVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVG---------- 1883

Query: 2469 XXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHY 2528
                   +E + P+              R E P        FT  L  P ++ EG++  +
Sbjct: 1884 SATRNFNVEIEVPKA-------------RDEAPS-------FTTTLK-PIDVTEGENHTF 1922

Query: 2529 EARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINR 2588
              RV    +PS+   WY N  E+    R RTT D     L +  +   DAG Y C A N 
Sbjct: 1923 ICRVHARPEPSV--TWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNP 1980

Query: 2589 AG 2590
             G
Sbjct: 1981 IG 1982



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 3/109 (2%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            V+   P+A     P FTTT   + ++E  +  F CR+    + S  V W+ N   ++   
Sbjct: 1891 VEIEVPKARD-EAPSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDG 1947

Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
            R +T  D     L +  +  +DAG Y C A+N  G+A  + ++ V  R+
Sbjct: 1948 RSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKRE 1996



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 3/110 (2%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            KP   +  K  EV+EG    +E  ++ V  PT  VEWY     V  G RF+ T +  Y  
Sbjct: 1998 KPVIKEVSKTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHT 2055

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDEQRL 2085
            L I     +   +Y C A N  G     + + + + +     +  DE+R+
Sbjct: 2056 LSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREYAPEFEDFDEKRI 2105



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 5/112 (4%)

Query: 3682 REEITIEDEKPNPPRFTVE--IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFA 3739
            R E+ I+ EK   P F  E   ++   +P+G  ++    V   G PT  I W+ +G P  
Sbjct: 2821 RGELHIK-EKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTV--TGSPTPHITWYKDGEPLD 2877

Query: 3740 TGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791
               R+   +      L I  +   DAG YTC A N+ G+A  + ++  +A +
Sbjct: 2878 DTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDVTAPK 2929



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/108 (28%), Positives = 46/108 (42%), Gaps = 3/108 (2%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            VD   P+ + G  P F+     +   E   +   C +        +++W  NGKP+ +  
Sbjct: 2923 VDVTAPKVK-GEAPSFSLELRPIAAIEEFDSKLICHVS--GKPKPQIKWTKNGKPVESDG 2979

Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
            R++T  D     L I  V   DAG Y C A+N  G  + S  L V  R
Sbjct: 2980 RLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            +PIF T L     + EG +    A V     P+  I+W+K+   +++  R+++ FD  +V
Sbjct: 3981 SPIFVTELSPLS-VTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFFDGHVV 4037

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
             L I  +  +D G Y     N  G A S+A + + + +
Sbjct: 4038 KLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEY 4075



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 22/68 (32%), Positives = 38/68 (55%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            +G+P+  V W ++GV +  ++R+          LN+  + P+D+GTY C A + LG    
Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236

Query: 1797 SSTLFVQS 1804
            S TL V++
Sbjct: 4237 SCTLDVKA 4244



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 2/93 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F   L+S+   E     F  R E  G P  +I+W  N Q +   SR  +        L
Sbjct: 4455 PGFKSALRSLDVTEDESAEF--RCEVSGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKL 4512

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
             +    +QD+G Y C AV+  G A + A L+V+
Sbjct: 4513 AITKATLQDTGVYKCLAVNDNGSATSTADLNVS 4545



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 5/106 (4%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           PQ     Q+  E+ EG + + +  LT    P   V WYKDG+P+  +  I          
Sbjct: 88  PQIKEKEQEPIEVFEGESVNLD--LTITGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF 145

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS---TVTADL 872
           L+I      D+G Y   A NK+G +     + V  +    TVT++L
Sbjct: 146 LSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSEL 191



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 59/242 (24%), Positives = 94/242 (38%), Gaps = 30/242 (12%)

Query: 1310 APQFSRA-LHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            AP+F+   L  IE  E   V++  RL   G+    V W+ +G  +    + +     D  
Sbjct: 378  APEFADGDLEPIEVKEDQAVNV--RLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVH 435

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK--KDLILESQHPSGLEK------ 1420
             L +      D G Y C+A+N LG    +  + V+ K    +I     P  + K      
Sbjct: 436  ELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKW 495

Query: 1421 --IQYLEDTSRYK------------KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFEC 1466
                 L+D   YK              DI  +   +KP F+ + + +   +E + V FE 
Sbjct: 496  SVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVEDV-TALETEQVWFEI 554

Query: 1467 KLEPVTDSNLKVEWFKNGQPVTIGHRF--RPIHDFGYVALDIIDLIAEDSGIYTCRAVNL 1524
             ++        VEW++    +  G RF      +    +L I +   EDSG Y C A N 
Sbjct: 555  PIQGY--PRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASND 612

Query: 1525 VG 1526
             G
Sbjct: 613  AG 614



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 1438 ESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH 1497
            E  ++KP  +T  +  +  +E +   F C+     +   ++EWF    P+  G RF    
Sbjct: 820  EDRSLKPEVITSMRDCD-CVEEETASFHCEFSGKPEP--EIEWFCGPNPIVPGGRFHVTE 876

Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            +    +L I DL  ED+G Y C A N  G
Sbjct: 877  EGNIQSLAISDLKLEDAGNYKCVASNAAG 905



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            +P     +++ D ++E +TA F C     G P  ++EWF     I    R   T +    
Sbjct: 825  KPEVITSMRDCDCVEE-ETASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQ 881

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
            S+ IS ++ ED G Y C ASN  G+
Sbjct: 882  SLAISDLKLEDAGNYKCVASNAAGK 906



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 48/227 (21%), Positives = 93/227 (40%), Gaps = 39/227 (17%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-S 695
            P+F     ++ A++G  ++  T +   G P  +I WLK+G+ +  ++    I  +G +  
Sbjct: 922  PEFEDWKDTIDALDGQDVNISTWVR--GKPKPEIVWLKDGEELR-NTMHVQIKCYGDLHG 978

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSK 755
            L +  ++ +D+G YTCRA +  G+      +      T+E   +  +T  ++ +LE    
Sbjct: 979  LVLYKVSPEDAGMYTCRAKNNAGIVSKDVTI------TVEALQKKGDTPTFMSKLE---- 1028

Query: 756  YQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
                               P++    + EG +      +T    P   V+W++D   I  
Sbjct: 1029 -------------------PIE----ITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKP 1063

Query: 816  SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            S R  + ++    +L +     +D G Y     N  G   S A + V
Sbjct: 1064 SRRFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV 1110



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/79 (26%), Positives = 38/79 (48%)

Query: 4085 EKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            E   ++  +++  P  V  + +    P       A  V EG+  R  C+V+G+P+P + W
Sbjct: 1289 EARNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTLEW 1348

Query: 4145 LLNGNTIVNGSRYKLTYDG 4163
            L N   + +  R+K  +DG
Sbjct: 1349 LKNNELLSDNDRFKTRFDG 1367



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 9/129 (6%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            +EV++  +  P    +L+    V EG      C+V    +P L  E+  N + L    RF
Sbjct: 1305 VEVKQEVMIAPEIRQQLQAED-VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRF 1361

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
               FD    +L I++    DA  Y V   N  G  +S      +AK  +I +  +PE LE
Sbjct: 1362 KTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSS------SAKLKVIRKCTKPEVLE 1415

Query: 2352 KIRELESAE 2360
            K+++++  E
Sbjct: 1416 KMKDVKGVE 1424



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 62/247 (25%), Positives = 100/247 (40%), Gaps = 29/247 (11%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P  ++EG+ A  +  +     P   VEW+ +GK L    R    +      L I  V  E
Sbjct: 3139 PVIVNEGEEA--QMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPE 3196

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDS--QHESALEKIQYLE-DDSRYKRAV- 1968
            D G Y C A +  G++  +  L+V+  +   + S     S L  ++ LE + +++   V 
Sbjct: 3197 DEGSYKCVASSTNGRSSRTFDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVS 3256

Query: 1969 ----------QDDSFVVEKPQF-----GK----PIKNAEVTEGHPVHLEATLTPVNDPTM 2009
                      +DD+ +  + +F     G+      +  +  E     LEA +  V  PT 
Sbjct: 3257 GEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPT- 3315

Query: 2010 RVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             VEW+     +  G R++         L I   + EDTG Y   ATN  G   T S V +
Sbjct: 3316 -VEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGS--TGSVVDL 3372

Query: 2070 DAKSGLY 2076
              K  L+
Sbjct: 3373 TVKERLF 3379



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 4/73 (5%)

Query: 1456 VIEGQHVHFECKLEPVTDSNL-KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            V EG+    E +   +T + L KVEWFKN +PV   H  R   D   + L +     ED+
Sbjct: 4764 VTEGESTALEVE---ITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDA 4820

Query: 1515 GIYTCRAVNLVGT 1527
            G+Y C  +N +GT
Sbjct: 4821 GLYRCTILNDLGT 4833



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 62/227 (27%), Positives = 90/227 (39%), Gaps = 37/227 (16%)

Query: 1310 APQFS--RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367
            AP+F     L  +  VEG  V L   ++  G     V+W+  GK + T      +   D 
Sbjct: 5440 APEFPDRETLEQVVGVEGREVELSTVVK--GLPRPSVKWYKEGKLLHTSKALTVSTSGDT 5497

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDT 1427
              + + S   E SG Y C+ATN  G           A +D +L  Q     E+      T
Sbjct: 5498 HYVWIPSAKHEHSGRYRCEATNSNGT----------AHRDFVLNIQAQVPAEQWVAPAFT 5547

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
            +  +  DI++   T   RF+         I G  V       PV      VEW+++ +PV
Sbjct: 5548 APLQHIDILEGDTT---RFIGE-------ITGVPV-------PV------VEWYRDDRPV 5584

Query: 1488 TIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            T  HR R   D   V L +      D+G++ C   N +GT   S  L
Sbjct: 5585 TRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASL 5631



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/103 (30%), Positives = 44/103 (42%), Gaps = 4/103 (3%)

Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH-TL 3747
            +E  + P    ++K  I+  EGG   FD  V   G P  R+DW+         +R   TL
Sbjct: 5634 NEGYSKPEINEKLK-KIEAFEGGEARFDLLV--TGFPPPRVDWYRGTTKITDCNRYSSTL 5690

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
               G  +L I  I   D G Y C A N++G  T+   +    K
Sbjct: 5691 TSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 6/109 (5%)

Query: 1301 VREDITVMQ---APQFS-RALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            +R D++V +   APQ   +    IE  EG +V+L+  +   G     V W+ +GKP++  
Sbjct: 75   LRGDLSVKEKQIAPQIKEKEQEPIEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKT 132

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                     D   L +    P DSG Y C+A N++G +     + V  K
Sbjct: 133  KSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVK 181



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 27/95 (28%), Positives = 52/95 (54%), Gaps = 8/95 (8%)

Query: 2366 EIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLI--PVGDPTLKVEWFRNEKLIEDSS 2423
            ++ EP   + P  T  + +I  I +G+    DC+LI    G+P  +VEWF++ K ++ + 
Sbjct: 721  KVAEP-QGETPTITTEMTDIQAI-DGE----DCKLICHVTGEPNPEVEWFKDGKPLKANH 774

Query: 2424 RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            R+  + +   ++++   ++ ED G Y C  SN+ G
Sbjct: 775  RLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFG 809



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 10/139 (7%)

Query: 3685 ITIE--DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742
            IT+E   +K + P F  +++  I++ EG      C V   G P   + WF +        
Sbjct: 1009 ITVEALQKKGDTPTFMSKLEP-IEITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSR 1065

Query: 3743 RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQG 3802
            R     D    AL +      D G Y C  TN +GS ++ A +T   K    L  ++ Q 
Sbjct: 1066 RFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKH---LRPEVLQK 1122

Query: 3803 MSGEKIKELERGRISDAPK 3821
            M  + ++ +E G+ + A K
Sbjct: 1123 M--DDVRTVEGGKANFAVK 1139



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 2/97 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P F   +K  +VTEG        +    +P+  V WY N   +    R +TT+D    
Sbjct: 1901 EAPSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETY 1958

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             L +     +D G Y C A+N +G+A  T+ + V+ +
Sbjct: 1959 KLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 4/109 (3%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            +  + V + ++ P   + E+  T  V EG TA  E +V  V  P   +E+YH    +   
Sbjct: 1987 TAEMTVNKREVKP--VIKEVSKTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDG 2042

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             RF +T +  Y +L I+    + A  Y   A N  G  T    + +T +
Sbjct: 2043 DRFQVTQEGDYHTLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITER 2091



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 83/352 (23%), Positives = 138/352 (39%), Gaps = 69/352 (19%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAG 980
            +++GGF +    L  +G+    V W KDG  +  +SR             I  V   D G
Sbjct: 2640 VRKGGFVNITFTL--MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTG 2697

Query: 981  HYTCRAYNAIGQATTSANLTIVTKKDIIA-ESQHPGGLEKIQYLEDASRYSKRTEEEVKI 1039
             Y C A+N +G +  S  + I   K + + +++ PG L                   + +
Sbjct: 2698 TYVCEAHNRLGSSFRSCTIEIKEPKSVDSTDTRAPGQL-------------------IPV 2738

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHD 1097
              K  F G        V G  A  +  V+ +SD+ + +EW+     +   ++  I    D
Sbjct: 2739 KHKFDFEG--------VPGGKARCDVLVK-KSDI-IDIEWFRGTNMLRDGDKYKILKSDD 2788

Query: 1098 FGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHI 1157
               ++L + +V  ED+G Y  V    AG+  +   + ++ +           L EK   +
Sbjct: 2789 GQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHIKEKQQAPLF-----LDEK---V 2840

Query: 1158 EESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNG 1217
             + KF  P  Q +E++KS  V   P  +     +G         EP+ D           
Sbjct: 2841 SQEKFSLP--QGQEMNKSFTVTGSPTPHITWYKDG---------EPLDDT---------- 2879

Query: 1218 RSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            R + + SR   YY      L I++    D G YT  A N +G+A+ S  V V
Sbjct: 2880 RRIDIRSRGNVYY------LGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 24/69 (34%), Positives = 32/69 (46%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W KDG P++ + RI          L I ++   DAG YTC A N IG A  S
Sbjct: 2861 GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920

Query: 997  ANLTIVTKK 1005
              + +   K
Sbjct: 2921 FEVDVTAPK 2929



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 2/113 (1%)

Query: 2751 DRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWF 2810
            +RIGA                    F   L  I   E  +    C+V  S  P  +I+W 
Sbjct: 2912 NRIGAAYRSFEVDVTAPKVKGEAPSFSLELRPIAAIEEFDSKLICHV--SGKPKPQIKWT 2969

Query: 2811 FNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             N KP+ S  R ++ +D     L I     +D+G Y C A+N+ G+ ++S +L
Sbjct: 2970 KNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAAL 3022



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 65/252 (25%), Positives = 100/252 (39%), Gaps = 19/252 (7%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            ++K   P F+  L  +E L EGE   F   ++   +P   VEW+ +   +K   RFRT+ 
Sbjct: 3226 KDKWSLPAFSSKLRPLETL-EGEKTKFVVNVS--GEPIPTVEWFKDDTPIKHEDRFRTYF 3282

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT----ASMKV-QGKR-------NI--I 3519
            D    +L    T   +  E    A+       T      S K+  G+R       N+  +
Sbjct: 3283 DGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTL 3342

Query: 3520 LESQLPKGMEGTIDKIAALE-GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFE 3578
            + S L     G    IA  E G +G+V  LT + E    PEF            +     
Sbjct: 3343 VISNLHMEDTGPYKIIATNEHGSTGSVVDLTVK-ERLFGPEFLEEEGVWNKVAKAGGFVN 3401

Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRH 3638
                   +    V W+ +G  L   +R+   +      + I G+   DAG Y C+A +R 
Sbjct: 3402 ISFTLKGNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRI 3461

Query: 3639 GEATVSCKLQVK 3650
            G A  SC L++K
Sbjct: 3462 GTAIRSCTLEIK 3473



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 3/91 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+F   + +++DV EG      C++   G P   ++WF + +      RV +        
Sbjct: 3687 PKFLSHL-NSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCT 3743

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L  + +  +D G Y C ATN+ GS +++A I
Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVI 3774



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 32/203 (15%)

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
            +G+P   + WF +G      SR+   +      L+I  +   DAG Y C A ++ G    
Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLG---- 4232

Query: 3782 TAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841
                TC     + +++  P+           RG    A K +          +++ + T 
Sbjct: 4233 ----TCFRSCTLDVKAVRPR-----------RGNEVQACKPQT---------SKMANVTA 4268

Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT--VYDMGFVSLDILYVYAEDS 3899
             E   V+ + R+     P   +EW+R  + +  G RY+T  + D G  SL I  V  EDS
Sbjct: 4269 VEGWKVQLDTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDS 4326

Query: 3900 GEYICRAVNDFGEDFTKATISCK 3922
            G Y   A N+ GE  T A ++ K
Sbjct: 4327 GSYRAVASNNLGEATTLAELTVK 4349



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH--DFSYVSLDI 2835
            S + N+   EG  +  +  +  +  P   +EWF   + +  G RYK+    D    SL I
Sbjct: 4261 SKMANVTAVEGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLII 4318

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            +    EDSG Y   A+N+ G ATT   L   G
Sbjct: 4319 SDVQLEDSGSYRAVASNNLGEATTLAELTVKG 4350



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 29/108 (26%), Positives = 57/108 (52%), Gaps = 4/108 (3%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP   ++L+++++ E + A F R  +  S A  +++W+ N++P+   SR   +++     
Sbjct: 4454 APGFKSALRSLDVTEDESAEF-RCEVSGSPAP-RIQWFMNDQPVSRDSRIITSSDGPVHK 4511

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAV-TSGIAIVHSK-KSIYLESQHE 1682
            L I     +D+G Y C A+N  G A  T+ + + H + K  ++E   E
Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLRE 4559



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 3/89 (3%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P FV ++ + T++ E E+T  E ++   G P  KVEWF N KP+ H +     +D   + 
Sbjct: 4753 PSFVIEL-TPTTVTEGESTALEVEIT--GTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIR 4809

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
            +       ED+G Y C   N  G   + A
Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMA 4838



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 28/196 (14%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            +V WY +   L   +R    +      L+I S   ED+GTY C A + LG+   S I  V
Sbjct: 4977 EVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCILDV 5036

Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729
                          A+P+    E+    Q            PV T  ++D +  E     
Sbjct: 5037 Q-------------AVPK----EEVDHGQ---------IVKPVITRKIRDAQGEEGSNIR 5070

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
            FE  +     P   VEW R  + +    +       G  +L +  V  +D+G+Y   A N
Sbjct: 5071 FEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATN 5128

Query: 1790 ELGEAVTSSTLFVQSK 1805
            + G + + + + V+ K
Sbjct: 5129 QAGSSTSRAEVVVKDK 5144



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 3/113 (2%)

Query: 754  SKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI 813
            +K+  Q    E   + P F++ L      +EG    F  ++T   +P   +EW +DG  +
Sbjct: 5233 AKFDVQIQAPEAAPKAPAFLKQLLPQNA-REGDVVKFSCKVTGYPEP--EIEWTRDGVSM 5289

Query: 814  TASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
             +  R+T+ ++  + +L+I +    D+G Y     N  G A S+A + V  ++
Sbjct: 5290 ESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKT 5342



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 23/69 (33%), Positives = 42/69 (60%), Gaps = 4/69 (5%)

Query: 2671 DPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
            +P   + W+K+G+ L  TT   ++S  D   +T  I  L +DD+G Y C+A + LG++  
Sbjct: 5765 NPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLT--IFGLTHDDTGTYVCEAQSRLGKSFR 5822

Query: 2729 TASIKIEDR 2737
            T ++K+E++
Sbjct: 5823 TYALKVEEQ 5831



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 2/103 (1%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    P+ K   ++ I + EG   + +  +   G     V W KDG+P+  +  I   
Sbjct: 81   VKEKQIAPQIKEKEQEPIEVFEGESVNLDLTIT--GKPKPEVVWYKDGKPLRKTKSIDLK 138

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                   L+I   T +D+G Y C A N IG +    ++ +  K
Sbjct: 139  STDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVK 181



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 10/154 (6%)

Query: 1413 QHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENV--IEGQHVHFECKLEP 1470
            Q   G  K++   D      T   D  VT KP      + +ENV  +EG    FE K + 
Sbjct: 249  QDDKGTYKVEITNDLGSISST--ADLEVTPKPAKPEVVRKMENVESVEGSDAFFEVKFKG 306

Query: 1471 VTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV--ALDIIDLIAEDSGIYTCRAVNLVGTD 1528
                  K EWF + + +    RF+   D      +L I DL  +DSG Y C A N  G  
Sbjct: 307  YPIP--KREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAG-- 362

Query: 1529 EVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
            E + R   +           +  LE I+V ED++
Sbjct: 363  ECNLRADLKVKNKPFAPEFADGDLEPIEVKEDQA 396



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 38/139 (27%), Positives = 56/139 (40%), Gaps = 11/139 (7%)

Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468
            +  VE+   K  V T  + + + + E E A F    +   +P  ++EW+     +  G R
Sbjct: 816  EVKVEDRSLKPEVIT-SMRDCDCVEE-ETASFHCEFSGKPEP--EIEWFCGPNPIVPGGR 871

Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGM 3528
            F    +     L IS    ED+G Y C A N  G+  T A +KV        E       
Sbjct: 872  FHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVN-------EKHFAPEF 924

Query: 3529 EGTIDKIAALEGYSGTVDT 3547
            E   D I AL+G    + T
Sbjct: 925  EDWKDTIDALDGQDVNIST 943



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 3/103 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V + + KPE  T ++D   ++E   A F       G     +EW     P+    R    
Sbjct: 819  VEDRSLKPEVITSMRDCDCVEEET-ASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVT 875

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                  +L I  + + DAG+Y C A NA G+ TT A L +  K
Sbjct: 876  EEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P  IT +     + E ++A + C     P+P   +EW+     +  G R+  + +    +
Sbjct: 826  PEVITSMRDCDCVEE-ETASFHCEFSGKPEPE--IEWFCGPNPIVPGGRFHVTEEGNIQS 882

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            L I  +  ED+G Y C A N  G+  +   L V  K
Sbjct: 883  LAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 55/234 (23%), Positives = 86/234 (36%), Gaps = 38/234 (16%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    PEF+   KD I   +G   +    +   G     + WLKDG  +  +  +   
Sbjct: 915  VNEKHFAPEFED-WKDTIDALDGQDVNISTWVR--GKPKPEIVWLKDGEELRNTMHVQIK 971

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
                   L +  V+  DAG YTCRA N  G  +    +T+                E +Q
Sbjct: 972  CYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITV----------------EALQ 1015

Query: 1022 YLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081
               D   +  +  E ++IT+   F              S +   R +P+      V+W+ 
Sbjct: 1016 KKGDTPTFMSKL-EPIEITEGDDF------------QLSCNVTGRPQPE------VQWFR 1056

Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            +   I  + R +  +D    AL +     +D GVY  V  N  G     A +TV
Sbjct: 1057 DEVLIKPSRRFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV 1110



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 2/99 (2%)

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD 1366
            VM AP+  + L   +  EG +  L C++    + T+  EW  N + +    RF+  ++  
Sbjct: 1311 VMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQ 1368

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
               L + +V   D+  Y     N  GE  +S  L+VI K
Sbjct: 1369 TGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK 1407



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 5/102 (4%)

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKT 2028
            +D + + E+ QF +P+   E+    PV +   +     PT  V W+ NG+ ++ G   + 
Sbjct: 1503 RDYAPIFEEKQFLEPL---EIQVRQPVEVSYHVRGRPKPT--VTWWKNGKELRDGKHVEI 1557

Query: 2029 TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
                 Y  L IL +  ED G+Y C A N VG A     V+V+
Sbjct: 1558 RSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVE 1599



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 2/97 (2%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP FT  +K I V E +   F  R+    +P   V W RN   I    R  T  D    
Sbjct: 1901 EAPSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETY 1958

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             L ++ +  +D+G Y C A N +G+A  ++ + V  +
Sbjct: 1959 KLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 91/388 (23%), Positives = 136/388 (35%), Gaps = 58/388 (14%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P    ++ D+ K  EG+ A F+  +     P   VEWF     +  G RY+   +     
Sbjct: 3031 PLITHKLHDM-KAYEGKEARFDIEVT--GHPSPTVEWFKGPSGISEGRRYQLMSN----- 3082

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401
                    E  G++  + ++    D      KC + +NL            G    + + 
Sbjct: 3083 --------EEQGKHSLIVSDLNADDD--GIYKCVA-QNL-----------AGKASTRAML 3120

Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461
            D + R      +EE+   PV          + EGE A  +  ++    P   VEW+ +GK
Sbjct: 3121 DVIARDFGPEFDEEESPKPVI---------VNEGEEA--QMMVSVRGRPKAVVEWFKDGK 3169

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ-----GKR 3516
             L    R           L I    PED G Y C A +  G +  T  + V+      K 
Sbjct: 3170 FLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRTFDLSVKVPKPKDKW 3229

Query: 3517 NIILESQLPKGMEGTI-DKIAALEGYSG----TVDTLTPEAESGNPPEFTTTPSDLI--L 3569
            ++   S   + +E    +K   +   SG    TV+    +    +   F T     +  L
Sbjct: 3230 SLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCML 3289

Query: 3570 SENSSAHFEC---RLIPVNDSSMR--VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQ 3624
                +  FEC   RL        R  VEWF     L  G R +         L I  ++ 
Sbjct: 3290 VFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHM 3349

Query: 3625 RDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             D G Y   ATN HG       L VK R
Sbjct: 3350 EDTGPYKIIATNEHGSTGSVVDLTVKER 3377



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 20/216 (9%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            VEW KDG+ +  S R+          L I  VT  D G Y C A +  G+++ + +L++ 
Sbjct: 3162 VEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRTFDLSVK 3221

Query: 1003 TKK-----DIIAESQHPGGLE-----KIQYLEDASRYSKRTEEEVK----ITQKPRFLGP 1048
              K      + A S     LE     K +++ + S     T E  K    I  + RF   
Sbjct: 3222 VPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTY 3281

Query: 1049 LKG-TNKIVEGQSAHFE---ARVEPQ--SDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
              G    +V  ++  FE   AR+E         TVEW+    ++    R +         
Sbjct: 3282 FDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYT 3341

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            L I+++  ED+G Y ++A N  G       +TV+ R
Sbjct: 3342 LVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKER 3377



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F   +    VTEG      A ++ V  P   ++WY +  P+   HR +T +D   V L
Sbjct: 3982 PIFVTELSPLSVTEGDYTKFVAHVSGV--PLPSIQWYKDDNPISSNHRIRTFFDGHVVKL 4039

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074
             I     ED G Y     N  G A +++ + V  + G
Sbjct: 4040 LIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYG 4076



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 4105 SKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG- 4163
            S  R  P FV     VT   G  A F  RV G P+P+++W  +   ++N  R+ ++ +G 
Sbjct: 4545 SHCRMKPTFVERLREVTTVFGGEASFSVRVKGFPRPKIVWYKDITRLINRGRFHISEEGD 4604

Query: 4164 MYHFDIPKTRQYDTG 4178
            +Y+  I    + D+G
Sbjct: 4605 LYNLTIENVGRDDSG 4619



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 3/87 (3%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            R +P F + L+ +  +  G+ A F  R+   G P  K+ W+++   + +  R   + +  
Sbjct: 4548 RMKPTFVERLREVTTVFGGE-ASFSVRV--KGFPRPKIVWYKDITRLINRGRFHISEEGD 4604

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGE 2459
              ++TI +V  +D G YMC  SN +G+
Sbjct: 4605 LYNLTIENVGRDDSGTYMCILSNAVGK 4631



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 2501 PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTT 2560
            P+ ++  P F   LT P+ + EG+    E  +   G P  + EW+ N   +K     R+ 
Sbjct: 4746 PEEDWSAPSFVIELT-PTTVTEGESTALEVEIT--GTPLPKVEWFKNDKPVKHDHLVRSY 4802

Query: 2561 HDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             D   + L +      DAGLY C  +N  G
Sbjct: 4803 FDGKVIRLIVRRTTLEDAGLYRCTILNDLG 4832



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 47/196 (23%), Positives = 78/196 (39%), Gaps = 29/196 (14%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            V WY +G  ++   R+ T        L+I S+ +ED+G Y   AR+  G+   S  +   
Sbjct: 4978 VIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCIL--- 5034

Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196
                 D  ++                  P  +++     KPV  + + +     EG NI 
Sbjct: 5035 -----DVQAV------------------PKEEVDHGQIVKPVITRKIRDAQG-EEGSNIR 5070

Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256
             E  ++    P   VEW+     +  G +++     G  +L I      DTG Y V A N
Sbjct: 5071 FEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATN 5128

Query: 1257 HLGSAHTSAIVRVIER 1272
              GS+ + A V V ++
Sbjct: 5129 QAGSSTSRAEVVVKDK 5144



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 22/96 (22%), Positives = 43/96 (44%), Gaps = 2/96 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P     +  + A++G        +   G+P  ++EW K+G+ ++A+ R    F    I+L
Sbjct: 730 PTITTEMTDIQAIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMIAL 787

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
               + ++D G Y C   +  G   + A + V  R+
Sbjct: 788 SFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDRS 823



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 2/69 (2%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVT--LSINSLRNDDSGIYTCKATNLLGEAVST 2729
            P  +IEW+     +T G R K   D    +  L I+ ++ DD+G   C ATN  G+ V  
Sbjct: 1144 PKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVR 1203

Query: 2730 ASIKIEDRH 2738
            A +++E+++
Sbjct: 1204 ADLEVEEKN 1212



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 6/113 (5%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            PE +  ++ +  + EG       ++    + TL  EWLK+   +  + R  T F+     
Sbjct: 1315 PEIRQQLQAE-DVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGT 1371

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV---TKKDIIAESQHPGGLE 1018
            LTI++VT+ DA  Y     N  G+ ++SA L ++   TK +++ + +   G+E
Sbjct: 1372 LTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDVKGVE 1424



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
            P + E++ K+ +  +G  A F  KL G P+P + W      + +  +Y    ++Q    S
Sbjct: 1411 PEVLEKM-KDVKGVEGDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQ--KYS 1467

Query: 131  LLIKQIGPGDEGEYTCTARNQYGE 154
            L IK +   D G Y C A N+ G+
Sbjct: 1468 LTIKDLNLQDIGTYKCIASNEAGK 1491



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 3/104 (2%)

Query: 762  IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
            + +   + P F   L+ + ++ EG N  F  ++    +P+  V WY++   I    R  +
Sbjct: 1895 VPKARDEAPSFTTTLKPI-DVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRT 1951

Query: 822  IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
             F+     L +  ++ +DAG Y   A N +G+A  TA + V  R
Sbjct: 1952 TFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 28/116 (24%), Positives = 60/116 (51%), Gaps = 7/116 (6%)

Query: 753  YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLT-PVSD-PTMRVEWYKDG 810
            Y  ++   +  +   + P F   L+ +  ++E     F+++L   VS  P  +++W K+G
Sbjct: 2918 YRSFEVDVTAPKVKGEAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNG 2972

Query: 811  RPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
            +P+ +  R+ + ++     L+I  +  +DAG+Y   A N  G   S+A++ V+ R+
Sbjct: 2973 KPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRRN 3028



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYV 1368
            P  +  LH+++  EG     +  ++  G  +  VEWF     I  G R++     E    
Sbjct: 3031 PLITHKLHDMKAYEGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKH 3088

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            +L +  +  +D G+Y C A N  G+A T   L VIA+
Sbjct: 3089 SLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIAR 3125



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 4/116 (3%)

Query: 1160 SKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS 1219
            SK  +    + + S+  P F+  L N   V EG +  L C++   G P   VEWF + + 
Sbjct: 3670 SKTFDVKAGVPDGSRVTPKFLSHL-NSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQL 3726

Query: 1220 VTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
            +T   R ++        L        D G Y   A N  GS  +SA++ V+ R+ I
Sbjct: 3727 ITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVI-VVNRASI 3781



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 57/223 (25%), Positives = 89/223 (39%), Gaps = 45/223 (20%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLND-FG 3751
            PR   + +D +D  +G    F  RVE  G P  ++ WFH      +  R  +  + D + 
Sbjct: 3783 PRIIEKPRD-VDAVDGTDAKFTVRVE--GFPQPKVTWFHESTKIVSRGRYEISRVGDLYS 3839

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
             +   ++Y++    G Y C ATN  G      K+T     D+  +   P  ++G      
Sbjct: 3840 LVIRGVEYLHV---GTYKCIATNDAG------KVTAHCHLDVTKQDFAPI-VAG------ 3883

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
                 S+ P  EPIV              V E   V     V  K  P   +EW+++G+L
Sbjct: 3884 -----SEMP--EPIV--------------VREGCEVSMMANVRGKPAPT--VEWFKDGQL 3920

Query: 3872 LPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDF 3914
            L + +         + +LD+L     DSG Y   A ND G  +
Sbjct: 3921 LSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAY 3963



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 3/100 (3%)

Query: 3687 IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHT 3746
            + +E  + P F +E+     V EG     +  VE  G P  +++WF N +P      V +
Sbjct: 4745 VPEEDWSAPSFVIELTPTT-VTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRS 4801

Query: 3747 LNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
              D   I L +      DAG Y C   N  G+A++ A ++
Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLS 4841



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 56/224 (25%), Positives = 91/224 (40%), Gaps = 43/224 (19%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P  T +I+D     EG  + F+  V+    P   ++W+      A G +       G  +
Sbjct: 5052 PVITRKIRD-AQGEEGSNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYS 5108

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L I  +   D G Y   ATN+ GS+T+ A++       +V +  L               
Sbjct: 5109 LTITGVQKDDTGSYKVVATNQAGSSTSRAEV-------VVKDKPL--------------- 5146

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG-KLLP 3873
                APK   + +T P  IT+          G +    V  +  PK  + WY++G K+L 
Sbjct: 5147 ----APKVAEMTATGPITITR----------GNQLNLNVTIRGKPKPSVVWYKDGNKILT 5192

Query: 3874 SGH-RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTK 3916
            S + + R+  D+    L IL+  +E +G Y C A +  G    K
Sbjct: 5193 SRNVQIRSCGDV--YHLIILFTKSEHAGTYSCEATSKLGNTSAK 5234



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 3/96 (3%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP FT  L+  D ++EG       ++     P   +EW+++   +T   RL++  D  +V
Sbjct: 5543 APAFTAPLQHID-ILEGDTTRFIGEITGVPVP--VVEWYRDDRPVTRDHRLRTYSDGRVV 5599

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             L +      D+G++ C   N LG   S+AS+ + +
Sbjct: 5600 ILLLRQTNISDAGVFKCVLRNDLGTVASSASLNVNE 5635



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR-TVYDMGFVS 3888
            P+   ++K     E    RF+  V     P  R++WYR    +   +RY  T+   G  S
Sbjct: 5640 PEINEKLKKIEAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMAS 5697

Query: 3889 LDILYVYAEDSGEYICRAVNDFGE 3912
            L I  +  ED G Y C AVN++GE
Sbjct: 5698 LTIRKIRQEDGGLYGCVAVNEYGE 5721



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 2/81 (2%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845
            +EG+   F C V     P   I W+ + +P+ +  R K + D +  +L I    ++D G 
Sbjct: 197  QEGEQYKFTCAVTGKPKPV--ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGT 254

Query: 2846 YTCKATNSKGSATTSGSLRCT 2866
            Y  + TN  GS +++  L  T
Sbjct: 255  YKVEITNDLGSISSTADLEVT 275



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 5/112 (4%)

Query: 1293 DAARRTKQVREDIT--VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            DA + T  +  D+   V+Q P+F + +  IE   G        ++  G    +V W+ + 
Sbjct: 612  DAGKTTALLNLDVNEKVVQ-PEFDKEVKPIEVKHGEEATTSLEIK--GKPKPKVTWYKDL 668

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             P+      +     D   L++++  P+D G Y C+ATN+ G A  S  ++V
Sbjct: 669  VPLLETRSIQLKSVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKV 720



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G  P  TT  +D+   +       C +    + +  VEWF +GKPL    R+    +   
Sbjct: 727  GETPTITTEMTDIQAIDGEDCKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERM 784

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
            + L    +   D G Y C  +N  G  + + +++V+ R
Sbjct: 785  IALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 5/100 (5%)

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
            +G++  L C +   G+P   VEWF +G+ +    R    ++   +AL        D G Y
Sbjct: 743  DGEDCKLICHVT--GEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRY 800

Query: 1251 TVRAVNHLGSAHTSAIVRVIERS---DIVTDTQNEQAIEQ 1287
                 N  GS  ++A V+V +RS   +++T  ++   +E+
Sbjct: 801  KCVISNVFGSVSSAAEVKVEDRSLKPEVITSMRDCDCVEE 840



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 3/99 (3%)

Query: 764 EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
           E  S +P+ I  ++D   ++E   A F  + +   +P   +EW+    PI    R     
Sbjct: 820 EDRSLKPEVITSMRDCDCVEE-ETASFHCEFSGKPEP--EIEWFCGPNPIVPGGRFHVTE 876

Query: 824 NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
                SL I  L+ EDAG+Y   A N  G+  + A ++V
Sbjct: 877 EGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKV 915



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 5/118 (4%)

Query: 2222 QLEAQGHSTRIEVEEPKIS--PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFY 2279
            ++ A   S  ++V  PK+    P F  ELR    + E   +   C V     P  +I++ 
Sbjct: 2913 RIGAAYRSFEVDVTAPKVKGEAPSFSLELRPIAAI-EEFDSKLICHVSG--KPKPQIKWT 2969

Query: 2280 HNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             NGK ++S  R    +D     L I     +DAG Y   A NA G  +S+ ++TV+ +
Sbjct: 2970 KNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALTVSRR 3027



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 5/96 (5%)

Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028
            K + P F  +++   ++ E ++ K  C ++  G P  +++W  NGKP+    R    YD 
Sbjct: 2931 KGEAPSFSLELRPIAAIEEFDS-KLICHVS--GKPKPQIKWTKNGKPVESDGRLRTDYD- 2986

Query: 4029 GYVAMNFGW-VYPEDSGEYLCRATNLYGMDETKAVI 4063
            G VA    W V  +D+G Y C A+N  G   + A +
Sbjct: 2987 GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAAL 3022



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 33/191 (17%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSR--ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXX 2461
            G+P   V W+R+  L+ D++R  I    D  YV+  I  +  ED G Y+C A + +G   
Sbjct: 3408 GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVN--IYGLTLEDAGNYVCEARSRIG--- 3462

Query: 2462 XXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELW 2521
                          LE        K+  +  P E++         K +  Q      +  
Sbjct: 3463 -------TAIRSCTLEI-------KVPSMGGPEEKK-------ISKALIGQG-DNDVQAV 3500

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT--THDFGFVTLDINSVVANDAG 2579
            EG    ++ R+   G P    EWY   ++L    +++   T + G  +L +N V  +D G
Sbjct: 3501 EGWKVQFQTRIT--GYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIG 3558

Query: 2580 LYMCKAINRAG 2590
             Y C A N AG
Sbjct: 3559 TYKCLATNSAG 3569



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 11/111 (9%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRY---RTFHDFG 3338
            P+ I + +DV   V+G  A F  R+     P  KV WF+   K+    RY   R    + 
Sbjct: 3783 PRIIEKPRDVDA-VDGTDAKFTVRVEGFPQP--KVTWFHESTKIVSRGRYEISRVGDLYS 3839

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE--NLILDSQLP 3387
            +VI  + Y +    G Y+C+ATN  G+ +   +L  T ++   ++  S++P
Sbjct: 3840 LVIRGVEYLHV---GTYKCIATNDAGKVTAHCHLDVTKQDFAPIVAGSEMP 3887



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 27/57 (47%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 4124 EGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK--LTYDGMYHFDIPKTRQYDTG 4178
            EG  ARF   VTG P PRV W      I + +RY   LT DGM    I K RQ D G
Sbjct: 5653 EGGEARFDLLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGG 5709



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 8/115 (6%)

Query: 3840 TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAED 3898
            TVE  E  RF+  +E    PK  +EWY+    + S  +++ + D  G  SL I  +  +D
Sbjct: 2    TVESGEA-RFDVTIEGY--PKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDD 58

Query: 3899 SGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPRGMKRSEALTQMEATI 3950
            +G Y C A ND G+   +  +S K+    P I  + Q P  +   E++  ++ TI
Sbjct: 59   AGAYKCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGESV-NLDLTI 112



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 5/116 (4%)

Query: 1174 KSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            K K   V     P  V EG+     C +   G P   + W+ +G+ +    R K  +D  
Sbjct: 181  KGKAPTVTSELKPDKVQEGEQYKFTCAVT--GKPKPVISWYKDGQPIKADRRVKDSFDGT 238

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI---ERSDIVTDTQNEQAIE 1286
               L I      D G Y V   N LGS  ++A + V     + ++V   +N +++E
Sbjct: 239  TSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVE 294



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F + + + I I EG    F+      G     V+W +D   ++ S R    ++    A
Sbjct: 1021 PTFMSKL-EPIEITEGD--DFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSA 1077

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            LT+K   + D G Y C   N  G  ++ A++T++ K
Sbjct: 1078 LTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 3/97 (3%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V  AP     L++ D + EG    L  +V    +P L  EW KN   L+   R K+ FD 
Sbjct: 1311 VMIAPEIRQQLQAED-VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDG 1367

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
               TL+I ++   D+  Y     N  GE  S+A +K+
Sbjct: 1368 QTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKV 1404



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            ++AP  T+ L+S  ++ E     L   V+   DP+   EW K+   +     L S+FD  
Sbjct: 1605 EEAPKLTSQLRSA-RITESDDFELACDVKGTPDPSY--EWLKDDKPVKFDRHLSSSFDGK 1661

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
              TL+   ++  D G YT    N  G   S+A++ I
Sbjct: 1662 KCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDI 1697



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 22/73 (30%), Positives = 34/73 (46%)

Query: 790  FEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVN 849
            FE        P    EW KD +P+     ++S F+    +LN   ++  D GSYTV   N
Sbjct: 1625 FELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKN 1684

Query: 850  KLGEAISTASIRV 862
              G   S+A++ +
Sbjct: 1685 AHGSTYSSANLDI 1697



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566
            KP+  +V +   E+ EG  A  E +V  V  P++  EWY     +  G RF+ T +  + 
Sbjct: 1998 KPVIKEV-SKTFEVSEGGTASIEVKVSGVPVPTV--EWYHGSNRVLDGDRFQVTQEGDYH 2054

Query: 2567 TLDINSVVANDAGLYMCKAINRAG 2590
            TL I  V    A  Y C A N AG
Sbjct: 2055 TLSIRDVGDQAAASYKCVAFNNAG 2078



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS--RVKTINDFGFV 3615
            PE    P+ L++ E + + F+ R+      +  VEWF+  + L  G   R+++  + G  
Sbjct: 2529 PEIIEKPAGLVIVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLY 2586

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             L +  V     G Y   A+N HG+A     L V  R
Sbjct: 2587 SLVVSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER 2623



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 2/91 (2%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
            G PT  I W K+G+ ++ + R     R     L +L+L  +D+G YTC A +  G A   
Sbjct: 2861 GSPTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRS 2920

Query: 724  AVLHVT-PRATIERTSQHPETLQYIQQLEDY 753
              + VT P+   E  S   E L+ I  +E++
Sbjct: 2921 FEVDVTAPKVKGEAPSFSLE-LRPIAAIEEF 2950



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 29/90 (32%), Positives = 44/90 (48%), Gaps = 7/90 (7%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLI--PVGDPTLKVEWFRNEKLIEDSSRITKT 2428
            V  + P F+  L+ I  I+E     FD +LI    G P  +++W +N K +E   R+   
Sbjct: 2930 VKGEAPSFSLELRPIAAIEE-----FDSKLICHVSGKPKPQIKWTKNGKPVESDGRLRTD 2984

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            +D     ++I  V  +D G Y C ASN  G
Sbjct: 2985 YDGIVAYLSIWQVSHDDAGTYECIASNAAG 3014



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 77/306 (25%), Positives = 119/306 (38%), Gaps = 27/306 (8%)

Query: 3502 GEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA-LEGYSGTVDTLTPEAESGNPP-E 3559
            G      S + QGK ++I+ S L    +G    +A  L G + T   L   A    P  +
Sbjct: 3074 GRRYQLMSNEEQGKHSLIV-SDLNADDDGIYKCVAQNLAGKASTRAMLDVIARDFGPEFD 3132

Query: 3560 FTTTPSDLILSENSSAHFECRLIPVNDSSMRV-EWFHNGKPLLTGSRVKTINDFGFVILE 3618
               +P  +I++E   A     ++ V      V EWF +GK L    R+   +      L 
Sbjct: 3133 EEESPKPVIVNEGEEAQM---MVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLV 3189

Query: 3619 IGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEET 3678
            I  V   D G Y C A++ +G ++ +  L VK  +    +  LP+ F S    ++ LE  
Sbjct: 3190 IYHVTPEDEGSYKCVASSTNGRSSRTFDLSVKVPKPKD-KWSLPA-FSSKLRPLETLEGE 3247

Query: 3679 LHK------REEI-TIE---DEKP--NPPRFTVEIKDNIDVPEGGPV-HFDC---RVEP- 3721
              K       E I T+E   D+ P  +  RF       + +        F+C   R+E  
Sbjct: 3248 KTKFVVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAH 3307

Query: 3722 -VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
              G P   ++WF        G R           L I  ++  D G Y   ATN+ GS  
Sbjct: 3308 VAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTG 3367

Query: 3781 TTAKIT 3786
            +   +T
Sbjct: 3368 SVVDLT 3373



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 55/220 (25%), Positives = 90/220 (40%), Gaps = 35/220 (15%)

Query: 922  KEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGH 981
            K GGF +    L+  G+    V W +DG  +  ++R+          + I  +T+ DAG+
Sbjct: 3395 KAGGFVNISFTLK--GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGN 3452

Query: 982  YTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQ 1041
            Y C A + IG A  S  L I        +    GG                  EE KI++
Sbjct: 3453 YVCEARSRIGTAIRSCTLEI--------KVPSMGG-----------------PEEKKISK 3487

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR---IQTYHDF 1098
                +G      + VEG    F+ R+         VEWY    ++  +++    QT  D 
Sbjct: 3488 --ALIGQGDNDVQAVEGWKVQFQTRITGYP--YPHVEWYRGTIKLHDSDKYKIAQTKED- 3542

Query: 1099 GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            G  +L +  V  +D G Y  +A N+AG +    ++ V+ +
Sbjct: 3543 GLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDVKDK 3582



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297
            K S P FVTEL   + V EG    F   V  V  P+  I++Y +   + S  R    FD 
Sbjct: 3978 KWSSPIFVTELSPLS-VTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFFDG 4034

Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              V L I     ED G+Y V   N  G  TS+  ++V
Sbjct: 4035 HVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 1/90 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P+FV+    ++V EG++ +F   V+G P P + W  + N I +  R +  +DG +    I
Sbjct: 3982 PIFVTELSPLSVTEGDYTKFVAHVSGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLI 4041

Query: 4170 PKTRQYDTGKIEVIXXXXXXXXXXXXXLKV 4199
             +    D G+ +V+             L V
Sbjct: 4042 GQITLEDQGQYKVVLKNESGSATSSAKLSV 4071



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 4/88 (4%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTS--IFRFGYISLDMLS 700
            + +VTA+EG K+  +TR+   G P   +EW +  + I    R+ +  +   G  SL +  
Sbjct: 4263 MANVTAVEGWKVQLDTRM--TGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISD 4320

Query: 701  LNIQDSGEYTCRAVSATGVAETKAVLHV 728
            + ++DSG Y   A +  G A T A L V
Sbjct: 4321 VQLEDSGSYRAVASNNLGEATTLAELTV 4348



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 3/102 (2%)

Query: 1034 EEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ 1093
            E+  K    P F   L+  + + E +SA F  R E        ++W+ N + ++  +RI 
Sbjct: 4446 EDVCKSALAPGFKSALRSLD-VTEDESAEF--RCEVSGSPAPRIQWFMNDQPVSRDSRII 4502

Query: 1094 TYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T  D     L I     +D+GVY  +A N  G A  +A + V
Sbjct: 4503 TSSDGPVHKLAITKATLQDTGVYKCLAVNDNGSATSTADLNV 4544



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 2932 EGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNK 2991
            E + E    P  +I+W+ N + + + SR   +SD     L +     +D+G+Y C A N 
Sbjct: 4473 EFRCEVSGSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAVND 4532

Query: 2992 RGEAFTSSTV---YCTSKDNLIER 3012
             G A +++ +   +C  K   +ER
Sbjct: 4533 NGSATSTADLNVSHCRMKPTFVER 4556



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 4/137 (2%)

Query: 1805 KASLQLESQHESALQKIQQLEDSSRYQRREDVEVA-VNQAPRFITQLNGPTKLSEGQSAH 1863
            K ++   +  ++ + K   + D+       D+ V+     P F+ +L   T +  G+ A 
Sbjct: 4511 KLAITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGE-AS 4569

Query: 1864 YECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923
            +  R++ +P P  ++ WY +   L +  R+  S +     L I  V  +DSG Y C   N
Sbjct: 4570 FSVRVKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSN 4627

Query: 1924 NLGQAVSSIRLNVQSKE 1940
             +G+     +L V+++E
Sbjct: 4628 AVGKETCRSQLVVEAEE 4644



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 25/75 (33%), Positives = 38/75 (50%)

Query: 799  DPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            +P   V WYKDG  ++ ++R+ +        LNI  L +EDAG+Y   A +KLG+   + 
Sbjct: 4973 NPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSC 5032

Query: 859  SIRVAARSTVTADLG 873
             + V A      D G
Sbjct: 5033 ILDVQAVPKEEVDHG 5047



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 3/88 (3%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V  + P  T  L+  D +QEG+   F C +   G P   + W+++ + I+   R+  + D
Sbjct: 180  VKGKAPTVTSELKP-DKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFD 236

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                ++ I  V+ +D+G Y    +N LG
Sbjct: 237  GTTSTLLIKDVKQDDKGTYKVEITNDLG 264



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            +AP  +  L   +  EG      C +   G     + W+ +G+PIK   R + +++    
Sbjct: 183  KAPTVTSELKPDKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFDGTTS 240

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
             L +  V  +D G Y  + TN LG   ++  L V  K
Sbjct: 241  TLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPK 277



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P   TS+++ +  E + A F        +   ++EW+    P+  G RF  T      +L
Sbjct: 826  PEVITSMRDCDCVEEETASFHCEFSGKPEP--EIEWFCGPNPIVPGGRFHVTEEGNIQSL 883

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
             I     ED+G Y C A NA G+  T     V+ K
Sbjct: 884  AISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            K VEG       ++     P+  IEW+     +  G R K + D    +L+I  L   D 
Sbjct: 1421 KGVEGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDI 1478

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRHW 2739
            G Y C A+N  G+    A +++++R +
Sbjct: 1479 GTYKCIASNEAGKVTQRAELEVKERDY 1505



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 5/102 (4%)

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR--TSND 1898
            N  P  IT      K  EG+ A ++  +  +P P   VEW+     +  G RY+  ++ +
Sbjct: 3028 NMRP-LITHKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEE 3084

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             G  +L +  +  +D G Y C A N  G+A +   L+V +++
Sbjct: 3085 QGKHSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIARD 3126



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 73/354 (20%), Positives = 136/354 (38%), Gaps = 26/354 (7%)

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI--HDFGYVALDIIDLIAEDSG 1515
            EG+   F+  +E     +  VEWFK    ++ G R++ +   + G  +L + DL A+D G
Sbjct: 3044 EGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDG 3101

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTT 1575
            IY C A NL G      + + R+  D++     + G E  +  E+  K    +  +E   
Sbjct: 3102 IYKCVAQNLAG------KASTRAMLDVI---ARDFGPEFDE--EESPKPVIVNEGEEAQM 3150

Query: 1576 QAPICTTSLKNVE-IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSR---FTETNN 1631
               +       VE  K+G+  +  RR+   S         ++  P   GS     + TN 
Sbjct: 3151 MVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNG 3210

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQL 1691
                  D+   +P+    ++  A +    +    +  +  +K+ ++ +     +P +   
Sbjct: 3211 RSSRTFDLSVKVPKPKDKWSLPAFS----SKLRPLETLEGEKTKFVVNVSGEPIPTVEWF 3266

Query: 1692 EDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGV 1751
            +D +   +H  +        V  +  +     E   A  EA +   G P+  VEW     
Sbjct: 3267 KDDTPI-KHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAHV--AGVPRPTVEWFLGSA 3323

Query: 1752 PIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             +    R           L +  ++ ED+G Y   A NE G   +   L V+ +
Sbjct: 3324 KLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKER 3377



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 2639 QQAPIFTTHLKSYDKLV-EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            Q AP    H    +  V EGQ + ++  ++ +  P L++ W+K+G  L    R+      
Sbjct: 3583 QYAPEIPGHEDRQELNVPEGQEINMDVVIKSK--PRLEVSWYKDGELLQDTKRIDIRSRG 3640

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733
                L I S   +DSG+Y C+  + LG +  T  +K
Sbjct: 3641 DHYYLVIPSAAPEDSGLYKCEGVSTLGTSSKTFDVK 3676



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            IV +EG  +    NV     PT  +EWF + + L +           Y +LD+  T + D
Sbjct: 3890 IVVREGCEVSMMANVRGKPAPT--VEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQAD 3947

Query: 2843 SGIYTCKATNSKGSATTSGSLRCT 2866
            SG Y   ATN  GSA    +L  T
Sbjct: 3948 SGTYKFVATNDLGSAYRIFNLNVT 3971



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 9/137 (6%)

Query: 1407 DLILESQHPSGLEKIQYLEDT-SRYK-----KTDIIDESVTIKPRFVTRPKSIENVIEGQ 1460
            DL+  +Q  SG  K     D  S Y+      T I  +     P FVT    + +V EG 
Sbjct: 3939 DLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTELSPL-SVTEGD 3997

Query: 1461 HVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCR 1520
            +  F   +  V   +  ++W+K+  P++  HR R   D   V L I  +  ED G Y   
Sbjct: 3998 YTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVV 4055

Query: 1521 AVNLVGTDEVSCRLTCR 1537
              N  G+   S +L+ R
Sbjct: 4056 LKNESGSATSSAKLSVR 4072



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 6/107 (5%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            +K   P FVT++ S  S+ E + TKF   ++  G P   ++W+ +  P+   +R    +D
Sbjct: 3977 EKWSSPIFVTEL-SPLSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFD 4033

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGI 4071
               V +  G +  ED G+Y     N  G   + A   V +  GKP I
Sbjct: 4034 GHVVKLLIGQITLEDQGQYKVVLKNESGSATSSAKLSVREEYGKPAI 4080



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 49/198 (24%), Positives = 79/198 (39%), Gaps = 32/198 (16%)

Query: 1477 KVEWFKNGQPVTIGHRF--RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            +V W+K+G  ++   R   R   D  Y  L+I  L +ED+G Y C A + +G    SC L
Sbjct: 4977 EVIWYKDGTLLSDTTRMDTRSRGDTHY--LNIFSLTSEDAGTYMCEARSKLGKCFRSCIL 5034

Query: 1535 TCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
                  D+    + E                    VD      P+ T  +++ + +EG  
Sbjct: 5035 ------DVQAVPKEE--------------------VDHGQIVKPVITRKIRDAQGEEGSN 5068

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
              FE  +   S     VEWY  +  L  G ++  +   G  +L I     +D+G+Y   A
Sbjct: 5069 IRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVA 5126

Query: 1655 INALGEAVTSGIAIVHSK 1672
             N  G + +    +V  K
Sbjct: 5127 TNQAGSSTSRAEVVVKDK 5144



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 3/109 (2%)

Query: 2482 EGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLR 2541
            E   K+       + + + P+   + P F + L  P    EG    +  +V   G P   
Sbjct: 5223 EATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLL-PQNAREGDVVKFSCKVT--GYPEPE 5279

Query: 2542 FEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             EW  +GV ++   R  T +D    TL I++    D+G+Y C   N +G
Sbjct: 5280 IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSG 5328



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 7/141 (4%)

Query: 1539 TTDIVRSTQNEAGLEQIQVLEDRSKYHRT-DM---VDEVTTQAPICTTSLKNVEIKEGQR 1594
            T +I+ +T ++ G  + +         R+ D+   V E   + P  TT + +++  +G+ 
Sbjct: 687  TLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVKVAEPQGETPTITTEMTDIQAIDGED 746

Query: 1595 AHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRA 1654
                  +    +   +VEW+ + KPLK+  R   +     +AL       ED G Y C  
Sbjct: 747  CKLICHV--TGEPNPEVEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVI 804

Query: 1655 INALGEAVTSGIAIVHSKKSI 1675
             N  G +V+S   +    +S+
Sbjct: 805  SNVFG-SVSSAAEVKVEDRSL 824



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 11/152 (7%)

Query: 992  QATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKG 1051
            +A+   N++ +T K+  AE    G  + +      S  SK     +K   +P  L  +  
Sbjct: 1068 KASYDGNVSALTVKE--AELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPEVLQKMDD 1125

Query: 1052 TNKIVEGQSAHFEARVE--PQSDLTMTVEWYFNGKQITSANR--IQTYHDFGYVALDIAS 1107
              + VEG  A+F  +++  P+ +    +EWY    +IT   R  I+T  +     L I  
Sbjct: 1126 V-RTVEGGKANFAVKIDAFPKPE----IEWYLGATKITDGGRFKIKTDKENCSYILFIDD 1180

Query: 1108 VRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139
            V+ +D+G     A NAAG+  + A + VE ++
Sbjct: 1181 VKLDDAGTVKCSATNAAGKTVVRADLEVEEKN 1212



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 4/109 (3%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            + DV V        + Q     +  EG  A++  +I+ +P P   +EWY     +  G R
Sbjct: 1105 KADVTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKPE--IEWYLGATKITDGGR 1162

Query: 1893 YRTSNDFGFAA--LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            ++   D    +  L I  V  +D+G   C A N  G+ V    L V+ K
Sbjct: 1163 FKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 6/107 (5%)

Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028
            K++ P+  +Q++S   + E +  +  C +   G P+   EW  + KP+      +  +D 
Sbjct: 1604 KEEAPKLTSQLRS-ARITESDDFELACDVK--GTPDPSYEWLKDDKPVKFDRHLSSSFDG 1660

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGIV 4072
                +NF  V   D G Y     N +G   + A   ++K+  KP I+
Sbjct: 1661 KKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSKPEIL 1707



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            + +SK++ P +  ++ DA  +E G+ A+F  ++  +PK  V W      I +G RY LT 
Sbjct: 1697 IVKSKSK-PEILETMKDAEGIETGK-AKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQ 1754

Query: 4162 ---DGMYHFDIPKTRQYDTGKIEVI 4183
               DG Y   I   R  D G  +++
Sbjct: 1755 DEEDGTYSVTINDLRLEDCGTYKIV 1779



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 765  QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSI 822
            ++  +P+ +  ++D   ++ G+ A F+ ++     P   VEWY     I    R  +T  
Sbjct: 1699 KSKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQD 1755

Query: 823  FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               G  S+ I  LR ED G+Y + A N +G+    A + V
Sbjct: 1756 EEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV 1795



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 3/94 (3%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            +PV      + E + EG  A  E +V  +  P  T++W+H   ++  G R++ T +  Y 
Sbjct: 1998 KPVIKEVSKTFE-VSEGGTASIEVKVSGVPVP--TVEWYHGSNRVLDGDRFQVTQEGDYH 2054

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             L I     + + +Y C A N  G       L +
Sbjct: 2055 TLSIRDVGDQAAASYKCVAFNNAGRTTYRADLVI 2088



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 1/48 (2%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
            K +KP +  +KM   +  E  +ARF+V F G P P + WYR +  ++N
Sbjct: 2284 KANKPKVI-EKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRN 2330



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 60/237 (25%), Positives = 89/237 (37%), Gaps = 24/237 (10%)

Query: 1057 EGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVY 1116
            EG+ A     V  +      VEW+ +GK +  + R+          L I  V  ED G Y
Sbjct: 3144 EGEEAQMMVSVRGRPKAV--VEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSY 3201

Query: 1117 TVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIE-----ESKFV-----EPM 1166
              VA +  G +  +  ++V+     D  S+      K R +E     ++KFV     EP+
Sbjct: 3202 KCVASSTNGRSSRTFDLSVKVPKPKDKWSLP-AFSSKLRPLETLEGEKTKFVVNVSGEPI 3260

Query: 1167 YQIEEISKSKPVFVQPL------SNPPPVSEGKNIHLEC---RLEP--MGDPTMRVEWFH 1215
              +E      P+  +             +   K    EC   RLE    G P   VEWF 
Sbjct: 3261 PTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFL 3320

Query: 1216 NGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
                +  G R++         L I +    DTG Y + A N  GS  +   + V ER
Sbjct: 3321 GSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKER 3377



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 31/197 (15%)

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR 1537
            V WFK+G  +    R           L+I  L  +D+G Y C A + +GT   SC L   
Sbjct: 4184 VFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSCTLD-- 4241

Query: 1538 STTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHF 1597
                 V++ +   G E +Q  + +                   T+ + NV   EG +   
Sbjct: 4242 -----VKAVRPRRGNE-VQACKPQ-------------------TSKMANVTAVEGWKVQL 4276

Query: 1598 ERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTCRAI 1655
            + R+         VEW+   + +  G R+      + G  +L I     EDSG+Y   A 
Sbjct: 4277 DTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVAS 4334

Query: 1656 NALGEAVTSGIAIVHSK 1672
            N LGEA T     V  K
Sbjct: 4335 NNLGEATTLAELTVKGK 4351



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 5/121 (4%)

Query: 3933 VPRGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQ-PPRFVTQIQSQTSLVEMETT 3991
            VP        + + E T +K T+   L +  + DV K    P F + ++S   + E E+ 
Sbjct: 4415 VPSASFEDSGIYKCETTSEKETTS-QLFDIHIEDVCKSALAPGFKSALRS-LDVTEDESA 4472

Query: 3992 KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRAT 4051
            +F C+++  G P  +++WF N +P+   +R     D     +       +D+G Y C A 
Sbjct: 4473 EFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDTGVYKCLAV 4530

Query: 4052 N 4052
            N
Sbjct: 4531 N 4531



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P FV  LR  T VF G+ A F  +V+    P  +I +Y +   L +  RFHI+ +    +
Sbjct: 4551 PTFVERLREVTTVFGGE-ASFSVRVKGF--PRPKIVWYKDITRLINRGRFHISEEGDLYN 4607

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
            L I++   +D+G Y     NA+G  T    + V A+
Sbjct: 4608 LTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAE 4643



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 50/204 (24%), Positives = 84/204 (41%), Gaps = 29/204 (14%)

Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264
            G+P   V W+ +G  ++  +R  T        L+I   TS D G Y   A + LG    S
Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031

Query: 1265 AIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVE 1324
             I+ V             QA+ + ++  D  +  K           P  +R + + +  E
Sbjct: 5032 CILDV-------------QAVPKEEV--DHGQIVK-----------PVITRKIRDAQGEE 5065

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G+N+  E  ++        VEW+     +  G +++ +      +L +  V  +D+G Y 
Sbjct: 5066 GSNIRFEIHVK--SHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYK 5123

Query: 1385 CQATNQLGEAVTSCALRVIAKKDL 1408
              ATNQ G + TS A  V+  K L
Sbjct: 5124 VVATNQAGSS-TSRAEVVVKDKPL 5146



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 6/132 (4%)

Query: 1007 IIAESQHPG--GLEKIQYLEDAS-RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHF 1063
            +  +S+H G    E    L + S ++  + +      + P FL  L   N   EG    F
Sbjct: 5210 LFTKSEHAGTYSCEATSKLGNTSAKFDVQIQAPEAAPKAPAFLKQLLPQNAR-EGDVVKF 5268

Query: 1064 EARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNA 1123
              +V    +    +EW  +G  + S  R+ T++D  +  L I +    DSG+Y    +N 
Sbjct: 5269 SCKVTGYPE--PEIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNN 5326

Query: 1124 AGEAQLSASMTV 1135
            +G A  SA + V
Sbjct: 5327 SGWASSSAELVV 5338



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            Q+     A   P F+         EG+  +F C+VTG+P+P + W  +G ++ +  R   
Sbjct: 5238 QIQAPEAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGYPEPEIEWTRDGVSMESDERVTT 5297

Query: 4160 TYDGMYH-FDIPKTRQYDTG 4178
             YDG +    I      D+G
Sbjct: 5298 WYDGEHSTLSIHNANHADSG 5317



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 6/125 (4%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P F+ Q+  Q +  E +  KF C++   G P  ++EW  +G  +    R T  YD  +  
Sbjct: 5249 PAFLKQLLPQNAR-EGDVVKFSCKVT--GYPEPEIEWTRDGVSMESDERVTTWYDGEHST 5305

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA 4092
            ++       DSG Y C   N  G   + A +   GK       +L  +MK +      EA
Sbjct: 5306 LSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK---TQRPRLSDNMKELFATVGGEA 5362

Query: 4093 SWQVT 4097
             ++VT
Sbjct: 5363 RFEVT 5367



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 5/121 (4%)

Query: 3976 VTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNF 4035
            VT       + E E  KF C  A  G P   + W+ +G+P+    R    +D     +  
Sbjct: 187  VTSELKPDKVQEGEQYKFTC--AVTGKPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLI 244

Query: 4036 GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQ 4095
              V  +D G Y    TN  G   + A ++ T KP      ++ + M+++E +   +A ++
Sbjct: 245  KDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPA---KPEVVRKMENVESVEGSDAFFE 301

Query: 4096 V 4096
            V
Sbjct: 302  V 302



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 29/229 (12%)

Query: 659 RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718
           R+   G+P  ++ W K+G  +  + +           L +   +  D G+Y C A +  G
Sbjct: 400 RLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLG 459

Query: 719 VAETKAVLHVTPRATIERTSQHPETLQYIQQ----------LEDYSKYQHQESIE----- 763
             +    + V P+            LQ  ++          L+D  +Y+ + + E     
Sbjct: 460 SPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVT 519

Query: 764 -------EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITAS 816
                  ++   +P+F+R ++D+  L E     FE  +     P   VEWY+    I   
Sbjct: 520 SLADINVQKAKVKPEFLRKVEDVTAL-ETEQVWFEIPIQGYPRPI--VEWYRGTTRIKDG 576

Query: 817 SRIT---SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            R T   S  N  Y SL I   R ED+G Y   A N  G+  +  ++ V
Sbjct: 577 GRFTISESEENDMY-SLVIDEARTEDSGPYKCVASNDAGKTTALLNLDV 624



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 54/209 (25%), Positives = 83/209 (39%), Gaps = 28/209 (13%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            +V W+K+G  +    + +         L I      D G Y C A N +G+ + + ++T 
Sbjct: 410  EVTWYKDGTQLHDTKKLKLKATGDVHELSIPKASTNDEGQYFCEASNPLGSPKRTFKVTV 469

Query: 1537 --RSTTDIVRS------TQNEAGLEQI--QVLEDRSKY--HRTDMVDEVTTQAPICTTSL 1584
              +    ++ S       + E G +      L+D  +Y    T+ V  VT+ A I     
Sbjct: 470  VPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDAGEYKVKVTNEVGSVTSLADINVQKA 529

Query: 1585 K----------NVEIKEGQRAHFERRLIPVSDATLK-VEWYHNNKPLKSGSRFT--ETNN 1631
            K          +V   E ++  FE   IP+       VEWY     +K G RFT  E+  
Sbjct: 530  KVKPEFLRKVEDVTALETEQVWFE---IPIQGYPRPIVEWYRGTTRIKDGGRFTISESEE 586

Query: 1632 FGFVALDIMSCLPEDSGTYTCRAINALGE 1660
                +L I     EDSG Y C A N  G+
Sbjct: 587  NDMYSLVIDEARTEDSGPYKCVASNDAGK 615



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 31/110 (28%), Positives = 44/110 (40%), Gaps = 9/110 (8%)

Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
            K +  S + EVIT        M+D    E + A F       G P+  +EW     PI  
Sbjct: 818  KVEDRSLKPEVITS-------MRDCDCVEEETASFHCEFS--GKPEPEIEWFCGPNPIVP 868

Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
              R     +    +L +  +  ED+G Y C A N  G+  T + L V  K
Sbjct: 869  GGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 3/88 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK  + WL++G  +  +  +          L +  V+PED+G YTCRA N  G     
Sbjct: 947  GKPKPEIVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKD 1006

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLE 1825
             T+ V+   +LQ +    + + K++ +E
Sbjct: 1007 VTITVE---ALQKKGDTPTFMSKLEPIE 1031



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 11/134 (8%)

Query: 1833 REDVEVAV-NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH 1891
            R D+EV   N AP F  +  G  ++ EG+ A     I   P P+  V WY +  V+    
Sbjct: 1203 RADLEVEEKNVAPSFHGR-QGRLRVKEGREASVYFEISGKPKPS--VTWYKDDVVIGDED 1259

Query: 1892 R----YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            R    Y   + + F    I     ED G Y C+A N++G A  +  ++V+ K+ ++   +
Sbjct: 1260 RNVDIYSRGSSYYFT---IKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPE 1316

Query: 1948 HESALEKIQYLEDD 1961
                L+     E D
Sbjct: 1317 IRQQLQAEDVTEGD 1330



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 45/244 (18%)

Query: 3684 EITIEDEKPNP--PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            E+ +E  KP    P+ T +++ +  + E       C V+   DP+   +W  + +P    
Sbjct: 1595 EVQVEGVKPKEEAPKLTSQLR-SARITESDDFELACDVKGTPDPSY--EWLKDDKPVKFD 1651

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801
              + +  D     L+   +   D G YT    N  GS  ++A +      DIV     P+
Sbjct: 1652 RHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANL------DIVKSKSKPE 1705

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861
             +  E +K+            E I +   KF  +IK++                   PK 
Sbjct: 1706 IL--ETMKD-----------AEGIETGKAKFDVKIKAY-------------------PKA 1733

Query: 3862 RIEWYRNGKLLPSGHRYRTVYDM--GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             +EWY     +  G RY    D   G  S+ I  +  ED G Y   A ND G+   +A +
Sbjct: 1734 EVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAEL 1793

Query: 3920 SCKK 3923
            + K+
Sbjct: 1794 TVKE 1797



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 25/93 (26%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            S L +    E D+    C+V+ + DP+   EW  ++KP+       S+ D    +L+   
Sbjct: 1612 SQLRSARITESDDFELACDVKGTPDPSY--EWLKDDKPVKFDRHLSSSFDGKKCTLNFKR 1669

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKN 2870
                D G YT    N+ GS  +S +L     K+
Sbjct: 1670 VQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKS 1702



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 5/96 (5%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FG 2165
            +P  L  +   E ++ G +A F+ +++    P   ++W+H   +I  G RY  T D   G
Sbjct: 1703 KPEILETMKDAEGIETG-KAKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDEEDG 1759

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              ++ I     ED GTY   A N +G+      L V
Sbjct: 1760 TYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV 1795



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 2/104 (1%)

Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629
            V +   +AP  TT+LK +++ EG+   F  R+    + +  V WY N   +    R   T
Sbjct: 1895 VPKARDEAPSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTT 1952

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
             +     L +     +D+G Y C A N +G+A  +    V+ ++
Sbjct: 1953 FDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKRE 1996



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA--RLKSTFDFGLVTLSINSLRNDD 2711
            +VEG     + ++  R  P  ++EWF     LT G   R++S  + GL +L ++ ++ D 
Sbjct: 2540 IVEGNDSRFDVRI--RGHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597

Query: 2712 SGIYTCKATNLLGEAVSTASIKIEDR 2737
            +G Y   A+N  G+A +   + + +R
Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTVNER 2623



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 3/67 (4%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVA-LDIMSCLPEDSGTYTCRAINALGEAVTSGIAI 1668
            +++W  N KP++S  R   T+  G VA L I     +D+GTY C A NA G  V+S  A+
Sbjct: 2965 QIKWTKNGKPVESDGRL-RTDYDGIVAYLSIWQVSHDDAGTYECIASNAAG-TVSSSAAL 3022

Query: 1669 VHSKKSI 1675
              S++++
Sbjct: 3023 TVSRRNM 3029



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 2/60 (3%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            +++W KNG+PV    R R  +D G VA L I  +  +D+G Y C A N  GT   S  LT
Sbjct: 2965 QIKWTKNGKPVESDGRLRTDYD-GIVAYLSIWQVSHDDAGTYECIASNAAGTVSSSAALT 3023



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 28/94 (29%), Positives = 43/94 (45%), Gaps = 4/94 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTM--HDFGYV 1768
            P+ T  + D++  E + A F+  +   G P   VEW +    I    R   M   + G  
Sbjct: 3031 PLITHKLHDMKAYEGKEARFDIEV--TGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKH 3088

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            +L +  +N +D G Y C A N  G+A T + L V
Sbjct: 3089 SLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDV 3122



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 60/231 (25%), Positives = 91/231 (39%), Gaps = 34/231 (14%)

Query: 3980 QSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG---YVAMNFG 4036
            +S   ++  E  + +  ++  G P   VEWF +GK  L+ +R   +   G   Y+ +   
Sbjct: 3135 ESPKPVIVNEGEEAQMMVSVRGRPKAVVEWFKDGK-FLYDSRRMGVRSCGNSHYLVIYH- 3192

Query: 4037 WVYPEDSGEYLCRATNLYG-----MDETKAVIKTTGKPGI-VYDSQL-PKHMKSIEKIRE 4089
             V PED G Y C A++  G      D +  V K   K  +  + S+L P      EK + 
Sbjct: 3193 -VTPEDEGSYKCVASSTNGRSSRTFDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKF 3251

Query: 4090 M---------EASWQVTPEQVVEESKAR-------CPPVFVSLPDAVTVEEGEWARFCCR 4133
            +            W      +  E + R       C  VF    D+    E   AR    
Sbjct: 3252 VVNVSGEPIPTVEWFKDDTPIKHEDRFRTYFDGRVCMLVFRKT-DSFECSE---ARLEAH 3307

Query: 4134 VTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTGKIEVI 4183
            V G P+P V W L    + +G RY+L   D +Y   I      DTG  ++I
Sbjct: 3308 VAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKII 3358



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   +  + V E  +A    ++   G P+  VEW ++   I  ++R+ +        L
Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMF--GKPEPTVEWFKDDQLITNNDRVRSSVVGNTCTL 3744

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
              + VN +D G Y C A N+ G + +SS + V ++AS+
Sbjct: 3745 IFETVNIQDRGAYRCTATNQEG-STSSSAVIVVNRASI 3781



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 2/79 (2%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            +G  A F  RVE    P +T  WFH   KI +  RY  +      +L I        GTY
Sbjct: 3796 DGTDAKFTVRVEGFPQPKVT--WFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTY 3853

Query: 2183 MCKATNKLGEAVNTCTLKV 2201
             C ATN  G+    C L V
Sbjct: 3854 KCIATNDAGKVTAHCHLDV 3872



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 22/77 (28%), Positives = 35/77 (45%)

Query: 1186 PPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSA 1245
            P P+   +   +       G P   VEWF +G+ ++  +         +  LD++  T A
Sbjct: 3887 PEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQA 3946

Query: 1246 DTGEYTVRAVNHLGSAH 1262
            D+G Y   A N LGSA+
Sbjct: 3947 DSGTYKFVATNDLGSAY 3963



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 7/132 (5%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P F+  L  T  + EG+S   E  VE        VEW+ N K +   + +++Y D   + 
Sbjct: 4753 PSFVIELTPTT-VTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIR 4809

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE---TRSSIDTSSIHRGLYEKTR-HIE 1158
            L +     ED+G+Y     N  G A   A ++V    T+  +          E T   +E
Sbjct: 4810 LIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAVEGTEVRLE 4869

Query: 1159 ESKFVEPMYQIE 1170
              KF  PM ++E
Sbjct: 4870 VIKFGCPMPKVE 4881



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 36/117 (30%), Positives = 51/117 (43%), Gaps = 6/117 (5%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F   L     + EG +  +   I   P P   VEWY + + +   HR RT +D    
Sbjct: 5543 APAFTAPLQH-IDILEGDTTRFIGEITGVPVPV--VEWYRDDRPVTRDHRLRTYSDGRVV 5599

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
             L +      D+G + C   N+LG   SS  LNV   E   +   +E  L+KI+  E
Sbjct: 5600 ILLLRQTNISDAGVFKCVLRNDLGTVASSASLNV--NEGYSKPEINEK-LKKIEAFE 5653



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 3/91 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P FT  ++ +ID+ EG    F   +   G P   ++W+ + RP     R+ T +D   + 
Sbjct: 5544 PAFTAPLQ-HIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVI 5600

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L +      DAG + C   N  G+  ++A +
Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASSASL 5631



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 55/246 (22%), Positives = 85/246 (34%), Gaps = 22/246 (8%)

Query: 778  DLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRA 837
            DL  ++   +     +LT   +P   V WYKDG  +  + ++          L+I     
Sbjct: 385  DLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKAST 444

Query: 838  EDAGSYTVRAVNKLGEAISTASIRVAARSTV-TADLGI-PEQRRYI-------------- 881
             D G Y   A N LG    T  + V  +      + G+ P Q R                
Sbjct: 445  NDEGQYFCEASNPLGSPKRTFKVTVVPKGVAPVIESGLMPLQVRKETGAKWSVNTTLDDA 504

Query: 882  -EKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDST 940
             E                   V ++  KPEF   ++D ++  E     FE  ++  G   
Sbjct: 505  GEYKVKVTNEVGSVTSLADINVQKAKVKPEFLRKVED-VTALETEQVWFEIPIQ--GYPR 561

Query: 941  LRVEWLKDGRPVEASSRITTFFN--FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSAN 998
              VEW +    ++   R T   +      +L I      D+G Y C A N  G+ T   N
Sbjct: 562  PIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLN 621

Query: 999  LTIVTK 1004
            L +  K
Sbjct: 622  LDVNEK 627



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 2666 VEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLL 2723
            +E +  P  K+ W+K+ V L  T   +LKS  D    TL I +   DD G Y C+ATN  
Sbjct: 652  LEIKGKPKPKVTWYKDLVPLLETRSIQLKSVGDEH--TLEIINATPDDEGKYKCEATNKA 709

Query: 2724 GEAVSTASIKIE 2735
            G A  +  IK++
Sbjct: 710  GTAFRSFDIKVK 721



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 1/53 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            P V   + D  TVE G+ A F  ++   PKP + W L    I +G R+K+  D
Sbjct: 1117 PEVLQKMDDVRTVEGGK-ANFAVKIDAFPKPEIEWYLGATKITDGGRFKIKTD 1168



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 43/158 (27%), Positives = 61/158 (38%), Gaps = 12/158 (7%)

Query: 3082 IEWFYNGKTIEASHR--IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLE 3139
            IEW+     I    R  I+T       +L I   K  D+GT  C ATN  G+  +   LE
Sbjct: 1148 IEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLE 1207

Query: 3140 CVDKSKGQKPRFTTHIQNIEGLKDGQ--SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR 3197
              +K+    P F    Q    +K+G+  S +FE +      P   + WY +   +    R
Sbjct: 1208 VEEKNVA--PSFHGR-QGRLRVKEGREASVYFEIS----GKPKPSVTWYKDDVVIGDEDR 1260

Query: 3198 -IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
             +   S        I   +  D G Y C A N  G  F
Sbjct: 1261 NVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAF 1298



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 35/140 (25%), Positives = 57/140 (40%), Gaps = 10/140 (7%)

Query: 2119 ENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAED 2178
            E++ EGD     C+V    +P  T++W  N + +    R++T  D     L I      D
Sbjct: 1324 EDVTEGDDCRLTCKVSGYPEP--TLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLAD 1381

Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE-AQGHSTRIEVEEP 2237
            +  Y     N  GE  ++  LKV      I     P  LEK++ ++  +G      V+  
Sbjct: 1382 AVPYKVVVRNDAGEVSSSAKLKV------IRKCTKPEVLEKMKDVKGVEGDEATFNVKLS 1435

Query: 2238 KISPPRFVTELRGTTHVFEG 2257
                P  +    GTT + +G
Sbjct: 1436 GYPSPD-IEWYYGTTRIRDG 1454



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 2/91 (2%)

Query: 2917 IAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDV 2976
            ++   ++ EG    +E  V+    P   +EWY     +  G RF++T +  + TL + DV
Sbjct: 2004 VSKTFEVSEGGTASIE--VKVSGVPVPTVEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDV 2061

Query: 2977 YERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
             ++ +  Y C A+N  G     + +  T ++
Sbjct: 2062 GDQAAASYKCVAFNNAGRTTYRADLVITERE 2092



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 41/149 (27%), Positives = 62/149 (41%), Gaps = 16/149 (10%)

Query: 2916 PIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVD 2975
            PIAA  +     + H+ G+ +P+      I+W  NGK +E   R +   D     L +  
Sbjct: 2943 PIAAIEEFDSKLICHVSGKPKPQ------IKWTKNGKPVESDGRLRTDYDGIVAYLSIWQ 2996

Query: 2976 VYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKE 3035
            V   D+G Y C A N  G   +SS     S+ N+     H        K+ +++    KE
Sbjct: 2997 VSHDDAGTYECIASNAAG-TVSSSAALTVSRRNMRPLITH--------KLHDMKAYEGKE 3047

Query: 3036 PGQQPDDDTGRPPEFTTVFKDIVDISEGQ 3064
              +   + TG P      FK    ISEG+
Sbjct: 3048 -ARFDIEVTGHPSPTVEWFKGPSGISEGR 3075



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 4/89 (4%)

Query: 1719 DIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYVALNMKYVN 1776
            D++  E     F+ R+   G P   VEW R  + +  S++  +    + G  +L +  V 
Sbjct: 3496 DVQAVEGWKVQFQTRI--TGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVT 3553

Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             +D GTY C A N  G +     L V+ K
Sbjct: 3554 KDDIGTYKCLATNSAGSSACRINLDVKDK 3582



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 36/115 (31%), Positives = 46/115 (40%), Gaps = 5/115 (4%)

Query: 1293 DAARRTKQVREDITVMQ-APQF--SRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCN 1349
            DA + T     D+T    AP    S     I   EG  V +   ++  G     VEWF +
Sbjct: 3860 DAGKVTAHCHLDVTKQDFAPIVAGSEMPEPIVVREGCEVSMMANVR--GKPAPTVEWFKD 3917

Query: 1350 GKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            G+ +   +        +Y  LDLL     DSG Y   ATN LG A     L V A
Sbjct: 3918 GQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTA 3972



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 2/71 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + EG++   +  +   G P  KVEWF+N+K ++    +    D   + + +     ED G
Sbjct: 4764 VTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIVRRTTLEDAG 4821

Query: 2448 VYMCRASNLLG 2458
            +Y C   N LG
Sbjct: 4822 LYRCTILNDLG 4832



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 33/133 (24%), Positives = 54/133 (40%), Gaps = 7/133 (5%)

Query: 1544 RSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA---PICTTSLKNVEIKEGQRAHFERR 1600
            R+T  +AGL +  +L D      + M D    +A   P     + +++  EG     E  
Sbjct: 4814 RTTLEDAGLYRCTILNDLGT--ASSMADLSVNRALTKPEVAEKMTDIDAVEGTEVRLE-- 4869

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            +I       KVEW+ +N  L +  R+T +       L I +C   D+G Y     N  G 
Sbjct: 4870 VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCTTNDTGPYKVIGTNECGI 4929

Query: 1661 AVTSGIAIVHSKK 1673
                   I+H ++
Sbjct: 4930 GGAVLNLIIHERE 4942



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 2/112 (1%)

Query: 1294 AARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPI 1353
            +A+   Q++      +AP F + L      EG  V   C++   G     +EW  +G  +
Sbjct: 5232 SAKFDVQIQAPEAAPKAPAFLKQLLPQNAREGDVVKFSCKV--TGYPEPEIEWTRDGVSM 5289

Query: 1354 KTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            ++  R    Y+ ++  L + +    DSG+Y C   N  G A +S  L V  K
Sbjct: 5290 ESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGK 5341



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 2/112 (1%)

Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021
            +++   +Q      + P F K +      EG  V     +T   +P   +EW  +G  ++
Sbjct: 5233 AKFDVQIQAPEAAPKAPAFLKQLLPQNAREGDVVKFSCKVTGYPEP--EIEWTRDGVSME 5290

Query: 2022 QGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
               R  T YD  +  L I  A   D+G Y C   N  G A +++ + V  K+
Sbjct: 5291 SDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAELVVGGKT 5342



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 3/101 (2%)

Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            G  Q P  + ++K     V G+  +   +V  +  P  KI W+K+ +TL +  R     +
Sbjct: 5340 GKTQRPRLSDNMKELFATVGGEARF---EVTMKATPKPKICWYKDEITLRSRDRYTMKEE 5396

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             G+ TL I  ++  DSG Y   A+N  G+      +++ ++
Sbjct: 5397 DGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK 5437



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 1056 VEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDF-GYVALDIASVRAEDSG 1114
            VE   A F+  +E       TVEWY    +I S+ + +   D  G  +L I  +  +D+G
Sbjct: 3    VESGEARFDVTIEGYPK--PTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAG 60

Query: 1115 VYTVVARNAAGEAQLSASMTVETR 1138
             Y  VA N AG+  L   ++V+ +
Sbjct: 61   AYKCVATNDAGQTSLRGDLSVKEK 84



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 2/99 (2%)

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            V+  P+  + ++  +VTEG    L   ++   +PT+  EW  N   +    RFKT +D  
Sbjct: 1311 VMIAPEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQ 1368

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
               L I      D   Y     N  GE  +++ +KV  K
Sbjct: 1369 TGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRK 1407



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 2/80 (2%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493
            EG+ A F  +L+    P+  +EWY+    ++ G R++   D     L I     +D G Y
Sbjct: 1424 EGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTY 1481

Query: 3494 LCRAYNNYGEAVTTASMKVQ 3513
             C A N  G+    A ++V+
Sbjct: 1482 KCIASNEAGKVTQRAELEVK 1501



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 6/91 (6%)

Query: 1585 KNVEIKEGQRA--HFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSC 1642
            K + ++EGQ A  +   R  P  D    VEWY  +  L S  +       G   L+I   
Sbjct: 2103 KRIAVREGQNAITNMTIRARPSPD----VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKA 2158

Query: 1643 LPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
              +D+GTY C+A N++G      I  V + K
Sbjct: 2159 TLDDAGTYICKATNSIGSTSRRIIVDVEALK 2189



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 4/72 (5%)

Query: 2388 IQEGQTAHFDCRLIPV-GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
            + EG+ A     ++ V G P   VEWF++ K + DS R+          + I HV  EDE
Sbjct: 3142 VNEGEEAQM---MVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDE 3198

Query: 2447 GVYMCRASNLLG 2458
            G Y C AS+  G
Sbjct: 3199 GSYKCVASSTNG 3210



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 18/57 (31%), Positives = 32/57 (56%)

Query: 4107 ARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            +R  P F+S  +++ V+EG+ A+  C++ G P+P V W  +   I N  R + +  G
Sbjct: 3683 SRVTPKFLSHLNSLDVDEGDSAKLTCKMFGKPEPTVEWFKDDQLITNNDRVRSSVVG 3739



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 20/63 (31%), Positives = 32/63 (50%)

Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            V+  ++A   P  +  P  V   +G  A+F  RV G P+P+V W      IV+  RY+++
Sbjct: 3773 VIVVNRASITPRIIEKPRDVDAVDGTDAKFTVRVEGFPQPKVTWFHESTKIVSRGRYEIS 3832

Query: 4161 YDG 4163
              G
Sbjct: 3833 RVG 3835



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 43/190 (22%), Positives = 75/190 (39%), Gaps = 29/190 (15%)

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
            G+    V W+ +G  +    R       D   L++ S+  ED+G Y C+A ++LG+   S
Sbjct: 4972 GNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRS 5031

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVI 1457
            C L                         D     K ++ D    +KP  +TR        
Sbjct: 5032 CIL-------------------------DVQAVPKEEV-DHGQIVKP-VITRKIRDAQGE 5064

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EG ++ FE  ++     +  VEW++    +  G +++     G  +L I  +  +D+G Y
Sbjct: 5065 EGSNIRFEIHVKSHPPPH--VEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSY 5122

Query: 1518 TCRAVNLVGT 1527
               A N  G+
Sbjct: 5123 KVVATNQAGS 5132



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA- 1369
            P+ +  L  IE  EG     +  L   G    RV+W+     I   +R+      D +A 
Sbjct: 5640 PEINEKLKKIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTSDGMAS 5697

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L +  +  ED G+Y C A N+ GE  +   L V
Sbjct: 5698 LTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHV 5730



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 8/102 (7%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDFGLVTLSINSLRND 2710
            ++ EG+ V L+  +  +  P  ++ W+K+G  L  T    LKST D     LSI     +
Sbjct: 99   EVFEGESVNLDLTITGKPKP--EVVWYKDGKPLRKTKSIDLKSTDDSYF--LSIPKATPN 154

Query: 2711 DSGIYTCKATNLLGEAVS--TASIKIEDRHWLLGESLHPDSL 2750
            DSG Y C+A N +G +      ++K++ +   +   L PD +
Sbjct: 155  DSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPDKV 196



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 4/97 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYV 1768
            P     M+++   E   A FE +    G P  + EW  +   IE S+R  +TT       
Sbjct: 281  PEVVRKMENVESVEGSDAFFEVKF--KGYPIPKREWFHDSKKIEPSSRFKITTDDTEQTS 338

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            +L +  +  +DSG Y C A NE GE    + L V++K
Sbjct: 339  SLVISDLRLDDSGAYQCIASNEAGECNLRADLKVKNK 375



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 20/63 (31%), Positives = 32/63 (50%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            VEW+ +GK + + +R+    +   +AL    ++ ED G Y  V  N  G    +A + VE
Sbjct: 761  VEWFKDGKPLKANHRLVPSFEERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVE 820

Query: 1137 TRS 1139
             RS
Sbjct: 821  DRS 823



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 5/106 (4%)

Query: 776  LQDLGELQE--GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSL-NI 832
            L+D GE  +   +        T + +P   V WYKDG  +  +SR T + + G +   NI
Sbjct: 2630 LEDDGEWSKVVRKGGFVNITFTLMGNPRPFVTWYKDGILLYDTSR-TDMRSRGDIQYCNI 2688

Query: 833  MHLRAEDAGSYTVRAVNKLGEAISTASIRV-AARSTVTADLGIPEQ 877
              +  ED G+Y   A N+LG +  + +I +   +S  + D   P Q
Sbjct: 2689 FFVGPEDTGTYVCEAHNRLGSSFRSCTIEIKEPKSVDSTDTRAPGQ 2734



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 21/65 (32%), Positives = 34/65 (52%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   I WY +G+ L+   R  + S      L ++++   D+G YTC+A N+ G A+ S  
Sbjct: 2863 PTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFE 2922

Query: 3001 VYCTS 3005
            V  T+
Sbjct: 2923 VDVTA 2927



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 2/70 (2%)

Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA-LDIIHATSADTGEYTVRAVNHLGSAHT 1263
            G P  +++W  NG+ V    R +T YD G VA L I   +  D G Y   A N  G+  +
Sbjct: 2960 GKPKPQIKWTKNGKPVESDGRLRTDYD-GIVAYLSIWQVSHDDAGTYECIASNAAGTVSS 3018

Query: 1264 SAIVRVIERS 1273
            SA + V  R+
Sbjct: 3019 SAALTVSRRN 3028



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 53/241 (21%), Positives = 92/241 (38%), Gaps = 33/241 (13%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            ++T+++    P     E   N     GG V+    ++  G+P   + W+ +G      +R
Sbjct: 3371 DLTVKERLFGPEFLEEEGVWNKVAKAGGFVNISFTLK--GNPRPHVVWYRDGILLYDTTR 3428

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
            +   +      ++I  +   DAG Y C A ++ G+A           R   LE ++P  M
Sbjct: 3429 MDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAI----------RSCTLEIKVPS-M 3477

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
             G + K++ +  I     +   V                E   V+F+ R+     P   +
Sbjct: 3478 GGPEEKKISKALIGQGDNDVQAV----------------EGWKVQFQTRITGYPYP--HV 3519

Query: 3864 EWYRNGKLLPSGHRYRTVY--DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISC 3921
            EWYR    L    +Y+     + G  SL +  V  +D G Y C A N  G    +  +  
Sbjct: 3520 EWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLDV 3579

Query: 3922 K 3922
            K
Sbjct: 3580 K 3580



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 2/75 (2%)

Query: 1585 KNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLP 1644
            + + + EGQ  + +  ++  S   L+V WY + + L+   R    +      L I S  P
Sbjct: 3595 QELNVPEGQEINMD--VVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAP 3652

Query: 1645 EDSGTYTCRAINALG 1659
            EDSG Y C  ++ LG
Sbjct: 3653 EDSGLYKCEGVSTLG 3667



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 4/101 (3%)

Query: 902  VPESTQ-KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITT 960
            VP+ ++  P+F + + + + + EG  A    ++   G     VEW KD + +  + R+ +
Sbjct: 3679 VPDGSRVTPKFLSHL-NSLDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRS 3735

Query: 961  FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                    L  ++V + D G Y C A N  G  ++SA + +
Sbjct: 3736 SVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVV 3776



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 3/91 (3%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P+F++ + S   + E ++ K  C++   G P   VEWF + + + + +R           
Sbjct: 3687 PKFLSHLNS-LDVDEGDSAKLTCKM--FGKPEPTVEWFKDDQLITNNDRVRSSVVGNTCT 3743

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
            + F  V  +D G Y C ATN  G   + AVI
Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVI 3774



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS--IFNFGYVSLNIMHLRAEDAG 841
            EG     + ++T    P   VEW++    IT   R  +  + + G  SL I  ++ ED+G
Sbjct: 4270 EGWKVQLDTRMTGYPVPI--VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSG 4327

Query: 842  SYTVRAVNKLGEAISTASIRVAAR 865
            SY   A N LGEA + A + V  +
Sbjct: 4328 SYRAVASNNLGEATTLAELTVKGK 4351



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 23/97 (23%), Positives = 51/97 (52%), Gaps = 3/97 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F+ ++++VT +  G+ A F  R+     P  K+ W+ +  +L +  R+    +  +  
Sbjct: 4551 PTFVERLREVTTVFGGE-ASFSVRVKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYN 4607

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            L I     ++SG Y C+ +N +G+++ ++ L   ++E
Sbjct: 4608 LTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEE 4644



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   L+    +  G+  +    V  +  P  KI W+K+   L    R   + +  L  
Sbjct: 4551 PTFVERLREVTTVFGGEASF---SVRVKGFPRPKIVWYKDITRLINRGRFHISEEGDLYN 4607

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L+I ++  DDSG Y C  +N +G+    + + +E
Sbjct: 4608 LTIENVGRDDSGTYMCILSNAVGKETCRSQLVVE 4641



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 2/97 (2%)

Query: 3830 PKFITQIKSHT-VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P+FI +   +  V  SEGV        + +P+  + WY++G LL    R  T        
Sbjct: 4945 PEFIDEEGEYVKVVRSEGVA-NITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHY 5003

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
            L+I  + +ED+G Y+C A +  G+ F    +  + +P
Sbjct: 5004 LNIFSLTSEDAGTYMCEARSKLGKCFRSCILDVQAVP 5040



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F + L +I   EGD   F   +  +  P   +EW+ +++P+    R ++  D   V L +
Sbjct: 5546 FTAPLQHIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVILLL 5603

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
              T   D+G++ C   N  G+  +S SL
Sbjct: 5604 RQTNISDAGVFKCVLRNDLGTVASSASL 5631



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 3553 ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK-TIND 3611
            E  + PE       +   E   A F+  L+       RV+W+     +   +R   T+  
Sbjct: 5635 EGYSKPEINEKLKKIEAFEGGEARFD--LLVTGFPPPRVDWYRGTTKITDCNRYSSTLTS 5692

Query: 3612 FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             G   L I  + Q D GLY C A N +GE T    L V
Sbjct: 5693 DGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHV 5730



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 1/77 (1%)

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL-TYD 4162
            + K   P +     + + V EGE       +TG PKP V+W  +G  +       L + D
Sbjct: 82   KEKQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPKPEVVWYKDGKPLRKTKSIDLKSTD 141

Query: 4163 GMYHFDIPKTRQYDTGK 4179
              Y   IPK    D+GK
Sbjct: 142  DSYFLSIPKATPNDSGK 158



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 2/86 (2%)

Query: 1720 IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPED 1779
            I V E ++ + +  +   G PK  V W ++G P+  +  +          L++    P D
Sbjct: 98   IEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPND 155

Query: 1780 SGTYTCRAINELGEAVTSSTLFVQSK 1805
            SG Y C A N++G +     + V+ K
Sbjct: 156  SGKYKCEAKNKIGTSARDFDVNVKVK 181



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 3/102 (2%)

Query: 630 EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
           EDR   P + I  ++    +E     F       G P  +IEW      I    RF    
Sbjct: 820 EDRSLKP-EVITSMRDCDCVEEETASFHCEFS--GKPEPEIEWFCGPNPIVPGGRFHVTE 876

Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
                SL +  L ++D+G Y C A +A G   T+A L V  +
Sbjct: 877 EGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            KPE +I    +   VE +      +   K +P+  IEW+     +  G RF +T +    
Sbjct: 825  KPE-VITSMRDCDCVEEETASFHCEFSGKPEPE--IEWFCGPNPIVPGGRFHVTEEGNIQ 881

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSK 3006
            +L + D+   D+G Y C A N  G+  T + +    K
Sbjct: 882  SLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 6/109 (5%)

Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            R E+ + +EK   P F  + KD ID  +G  V+    V   G P   I W  +G      
Sbjct: 910  RAELKV-NEKHFAPEFE-DWKDTIDALDGQDVNISTWVR--GKPKPEIVWLKDGEELRNT 965

Query: 3742 SRVHTLNDFGFI-ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
              V  +  +G +  L +  +   DAG YTCRA N  G  +    IT  A
Sbjct: 966  MHVQ-IKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVEA 1013



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EGD+    C V    +PTL  EW  NN+ L    R+K+  D    +L I +    D+  Y
Sbjct: 1328 EGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPY 1385

Query: 2847 TCKATNSKGSATTSGSLR 2864
                 N  G  ++S  L+
Sbjct: 1386 KVVVRNDAGEVSSSAKLK 1403



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 2916 PIAAEHQLVEGQVLHLEGQVEP----KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTL 2971
            PI  E Q +E   + +   VE     +  P   + W+ NGK L  G   ++ S   + TL
Sbjct: 1507 PIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTL 1566

Query: 2972 DLVDVYERDSGIYTCKAYNKRGEA 2995
             ++   E D+G Y C A N  G A
Sbjct: 1567 YILRSEEEDAGSYKCLARNDVGSA 1590



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 5/105 (4%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--IT 959
            + +S  KPE    +KD   I E G A F+ +++    +   VEW      +    R  +T
Sbjct: 1697 IVKSKSKPEILETMKDAEGI-ETGKAKFDVKIKAYPKA--EVEWYHRSARIYDGGRYCLT 1753

Query: 960  TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                 G  ++TI  + + D G Y   A+N IG+ +  A LT+  K
Sbjct: 1754 QDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F   LK +   EG    F  R+    +P+  + W +N   I    R  + F      L
Sbjct: 1903 PSFTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETYKL 1960

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
             +  + I+D+G+Y C A +  G A   A + V  R
Sbjct: 1961 ILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKR 1995



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFN 963
            E  + P FK+ ++  I ++EGG        E  G     ++W+KD  PV    R+   F+
Sbjct: 2428 EQWEAPSFKSQLQPVI-LEEGGTGVLVG--EVAGKPLPTIQWMKDDYPVLFGHRVRPQFD 2484

Query: 964  FGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997
                 +  +   + D G Y C   N  G+A++ A
Sbjct: 2485 GRTCKVIFREALIGDGGMYECIIKNQCGEASSKA 2518



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 4/74 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED--SSRITKTHDFGYVSMTISHVRDED 2445
            I EG  + FD R+   G PT +VEWF   + + D    RI    + G  S+ +S V+ + 
Sbjct: 2540 IVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597

Query: 2446 EGVYMCRASNLLGE 2459
             G Y   ASN  G+
Sbjct: 2598 TGHYRIVASNEHGK 2611



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 4/68 (5%)

Query: 3858 DPKLRIEWYRNGKLLPSGHR--YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT 3915
            +P+  + WY++G LL    R   R+  D+ + +  I +V  ED+G Y+C A N  G  F 
Sbjct: 2655 NPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCN--IFFVGPEDTGTYVCEAHNRLGSSFR 2712

Query: 3916 KATISCKK 3923
              TI  K+
Sbjct: 2713 SCTIEIKE 2720



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 4/108 (3%)

Query: 2795 CNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSLDITHTYEEDSGIYTCKATN 2852
            C+V   +   + IEWF     L  G +YK   + D   +SL + +   ED+G Y C    
Sbjct: 2754 CDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHT 2813

Query: 2853 SKGSATTSGSLRCTGDKN--IYFDTQHPQGKAGLEAVEQAEEARLAKG 2898
              G  T  G L     +   ++ D +  Q K  L   ++  ++    G
Sbjct: 2814 PAGQTTIRGELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTG 2861



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 27/99 (27%), Positives = 38/99 (38%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            +EK +AP+F     + E     +        T T  P   + WY +G+ L    R     
Sbjct: 2827 KEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRIDIRS 2886

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
                  L I    PED+G Y C A N  G A  +  + V
Sbjct: 2887 RGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 31/128 (24%), Positives = 48/128 (37%), Gaps = 3/128 (2%)

Query: 4092 ASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            A+  V+    +  S+    P+       +   EG+ ARF   VTGHP P V W    + I
Sbjct: 3012 AAGTVSSSAALTVSRRNMRPLITHKLHDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGI 3071

Query: 4152 VNGSRYKLTYD---GMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRG 4208
              G RY+L  +   G +   +      D G  + +             L VI R      
Sbjct: 3072 SEGRRYQLMSNEEQGKHSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIARDFGPEF 3131

Query: 4209 VLKNAPRP 4216
              + +P+P
Sbjct: 3132 DEEESPKP 3139



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 36/130 (27%), Positives = 56/130 (43%), Gaps = 9/130 (6%)

Query: 1408 LILESQHP--SGLEKIQYLEDTSRYKKT-DI---IDESVTIKPRFVTRPKSIENVIEGQH 1461
            L++ S  P  SGL K + +       KT D+   + +   + P+F++   S++ V EG  
Sbjct: 3645 LVIPSAAPEDSGLYKCEGVSTLGTSSKTFDVKAGVPDGSRVTPKFLSHLNSLD-VDEGDS 3703

Query: 1462 VHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
                CK+    +    VEWFK+ Q +T   R R         L    +  +D G Y C A
Sbjct: 3704 AKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTA 3761

Query: 1522 VNLVGTDEVS 1531
             N  G+   S
Sbjct: 3762 TNQEGSTSSS 3771



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 2/92 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P     P D+   + + A F  R+        +V WFH    +++  R +         L
Sbjct: 3783 PRIIEKPRDVDAVDGTDAKFTVRV--EGFPQPKVTWFHESTKIVSRGRYEISRVGDLYSL 3840

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I GV     G Y C ATN  G+ T  C L V
Sbjct: 3841 VIRGVEYLHVGTYKCIATNDAGKVTAHCHLDV 3872



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 20/70 (28%), Positives = 34/70 (48%)

Query: 2136 INDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVN 2195
            + +P   + WF +G ++    R           L+I     +D+GTY+C+A ++LG    
Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236

Query: 2196 TCTLKVAGHR 2205
            +CTL V   R
Sbjct: 4237 SCTLDVKAVR 4246



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATL-KVEWYHNNKPLKSGSRFTE 1628
            V E    AP     L    + EG+    E   + ++   L KVEW+ N+KP+K       
Sbjct: 4745 VPEEDWSAPSFVIELTPTTVTEGESTALE---VEITGTPLPKVEWFKNDKPVKHDHLVRS 4801

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
              +   + L +     ED+G Y C  +N LG A
Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTA 4834



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 1/94 (1%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F      Y K+V  + V        R +P  ++ W+K+G  L+   R+ +        
Sbjct: 4945 PEFIDEEGEYVKVVRSEGV-ANITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHY 5003

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            L+I SL ++D+G Y C+A + LG+   +  + ++
Sbjct: 5004 LNIFSLTSEDAGTYMCEARSKLGKCFRSCILDVQ 5037



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 2/86 (2%)

Query: 780  GELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAE 838
            G +   R       +T    P   V WYKDG  I  +SR   I + G V  L I+  ++E
Sbjct: 5157 GPITITRGNQLNLNVTIRGKPKPSVVWYKDGNKIL-TSRNVQIRSCGDVYHLIILFTKSE 5215

Query: 839  DAGSYTVRAVNKLGEAISTASIRVAA 864
             AG+Y+  A +KLG   +   +++ A
Sbjct: 5216 HAGTYSCEATSKLGNTSAKFDVQIQA 5241



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            + EG       +V    + T+  EW  N + ++  +R +T  D     L I +V   D+ 
Sbjct: 1326 VTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAV 1383

Query: 1115 VYTVVARNAAGEAQLSASMTV 1135
             Y VV RN AGE   SA + V
Sbjct: 1384 PYKVVVRNDAGEVSSSAKLKV 1404



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 3/113 (2%)

Query: 3812 ERGRISDAPKEEPIVS-TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK 3870
            + G +S + K + I   T P+ + ++K     E +   F  ++     P   IEWY    
Sbjct: 1392 DAGEVSSSAKLKVIRKCTKPEVLEKMKDVKGVEGDEATFNVKLSGYPSPD--IEWYYGTT 1449

Query: 3871 LLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             +  G RY+   D    SL I  +  +D G Y C A N+ G+   +A +  K+
Sbjct: 1450 RIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKE 1502



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 2910 KPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFV 2969
            KPE ++    + + VEG       ++     PD  IEWY+    +  G R+K + D    
Sbjct: 1410 KPE-VLEKMKDVKGVEGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDDQKY 1466

Query: 2970 TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKD 3007
            +L + D+  +D G Y C A N+ G+    + +    +D
Sbjct: 1467 SLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKERD 1504



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 22/95 (23%), Positives = 41/95 (43%)

Query: 2364 RPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS 2423
            R E+     +Q P+F     + +     Q    +      G PT  + W+++ + ++D+ 
Sbjct: 2821 RGELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTR 2880

Query: 2424 RITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            RI          + I +++ ED G Y C A N +G
Sbjct: 2881 RIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIG 2915



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 59/249 (23%), Positives = 102/249 (40%), Gaps = 27/249 (10%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            S P F   L  P    EG+       +   G+P   VEWF +   +    RF+TY+D G 
Sbjct: 3230 SLPAFSSKL-RPLETLEGEKTKFVVNVS--GEPIPTVEWFKDDTPIKHEDRFRTYFD-GR 3285

Query: 1235 VALDIIHAT-SADTGEYTVRA---------VN-HLGSAHTSAIVRV-IERSD----IVTD 1278
            V + +   T S +  E  + A         V   LGSA      R  +E++D    +V  
Sbjct: 3286 VCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVIS 3345

Query: 1279 TQNEQAIEQIQLLEDAARRTKQVREDITVMQ---APQF--SRALHNIETVEGTNVHLECR 1333
              + +     +++      +     D+TV +    P+F     + N     G  V++   
Sbjct: 3346 NLHMEDTGPYKIIATNEHGSTGSVVDLTVKERLFGPEFLEEEGVWNKVAKAGGFVNISFT 3405

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            L+  G+    V W+ +G  +    R       D   +++  +  ED+G Y C+A +++G 
Sbjct: 3406 LK--GNPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGT 3463

Query: 1394 AVTSCALRV 1402
            A+ SC L +
Sbjct: 3464 AIRSCTLEI 3472



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 20/81 (24%), Positives = 37/81 (45%)

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
            +E   A+ +  +    +PT++W    A + +   +++    N   L+I N + EDTG + 
Sbjct: 3297 FECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYK 3356

Query: 4793 CRATTAAGQVETSAKLVVKSK 4813
              AT   G   +   L VK +
Sbjct: 3357 IIATNEHGSTGSVVDLTVKER 3377



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 1/69 (1%)

Query: 4116 LPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY-HFDIPKTRQ 4174
            +P+ + V EG        V G P P V W  +G  + N +   L   G Y + D+ KT Q
Sbjct: 3886 MPEPIVVREGCEVSMMANVRGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQ 3945

Query: 4175 YDTGKIEVI 4183
             D+G  + +
Sbjct: 3946 ADSGTYKFV 3954



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 3/82 (3%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            + P F +  +S++ V E +   F C++        +++WF N QPV+   R     D   
Sbjct: 4453 LAPGFKSALRSLD-VTEDESAEFRCEVSGSPAP--RIQWFMNDQPVSRDSRIITSSDGPV 4509

Query: 1502 VALDIIDLIAEDSGIYTCRAVN 1523
              L I     +D+G+Y C AVN
Sbjct: 4510 HKLAITKATLQDTGVYKCLAVN 4531



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F+  L+ VT + GG+  F  R++  G P  KI W K+   +    RF         +L
Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRVK--GFPRPKIVWYKDITRLINRGRFHISEEGDLYNL 4608

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             + ++   DSG Y C   +A G    ++ L V
Sbjct: 4609 TIENVGRDDSGTYMCILSNAVGKETCRSQLVV 4640



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 3/105 (2%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            V+   PE E  + P F    +   ++E  S   E  +        +VEWF N KP+    
Sbjct: 4741 VEGHVPE-EDWSAPSFVIELTPTTVTEGESTALEVEI--TGTPLPKVEWFKNDKPVKHDH 4797

Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             V++  D   + L +      DAGLY C   N  G A+    L V
Sbjct: 4798 LVRSYFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSV 4842



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 54/204 (26%), Positives = 75/204 (36%), Gaps = 40/204 (19%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL-NDFGFIALDIDYIYARDAGE 3767
            E G   FD  +E    PT  ++W+       +  +   L +D G  +L I  +   DAG 
Sbjct: 4    ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61

Query: 3768 YTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVS 3827
            Y C ATN  G  +    ++       V E Q+       +IKE E         +EPI  
Sbjct: 62   YKCVATNDAGQTSLRGDLS-------VKEKQI-----APQIKEKE---------QEPI-- 98

Query: 3828 TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887
                         V E E V  +  +  K  PK  + WY++GK L               
Sbjct: 99   ------------EVFEGESVNLDLTITGK--PKPEVVWYKDGKPLRKTKSIDLKSTDDSY 144

Query: 3888 SLDILYVYAEDSGEYICRAVNDFG 3911
             L I      DSG+Y C A N  G
Sbjct: 145  FLSIPKATPNDSGKYKCEAKNKIG 168



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 26/123 (21%), Positives = 55/123 (44%), Gaps = 5/123 (4%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            + V+E +I+P +   + +    VFEG++ + +  +     P   + +Y +GK L+     
Sbjct: 79   LSVKEKQIAP-QIKEKEQEPIEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKTKSI 135

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGS--IISESQRPEG 2349
             +        L I    P D+G+Y  +A N +G       + V  KG    ++   +P+ 
Sbjct: 136  DLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPDK 195

Query: 2350 LEK 2352
            +++
Sbjct: 196  VQE 198



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRT-DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERR 1600
            I ++T N++G  + +         R  D+  +V  +AP  T+ LK  +++EG++  F   
Sbjct: 148  IPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPDKVQEGEQYKFTCA 207

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            +         + WY + +P+K+  R  ++ +     L I     +D GTY     N LG
Sbjct: 208  VTGKPKPV--ISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLG 264



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 3/88 (3%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG-YVSLNIMHLRAEDA 840
            ++EGR A    +++    P+  V WYKD   I    R   I++ G      I   R ED 
Sbjct: 1226 VKEGREASVYFEISGKPKPS--VTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDK 1283

Query: 841  GSYTVRAVNKLGEAISTASIRVAARSTV 868
            G+Y   A N +G A  T  I V  +  V
Sbjct: 1284 GTYKCEARNDVGTAFETFPIDVEVKQEV 1311



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V W+ NGK L  G  V+  +   +  L I    + DAG Y C A N  G A    ++QV+
Sbjct: 1540 VTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVE 1599

Query: 3651 GRQGIILEPQLPSHFKSG--TES 3671
            G +     P+L S  +S   TES
Sbjct: 1600 GVKPKEEAPKLTSQLRSARITES 1622



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            +PV  +  +  + + EG TA  + ++  V  PT  VEW+     + D  R   T +  Y 
Sbjct: 1998 KPVIKEVSKTFE-VSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYH 2054

Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458
            +++I  V D+    Y C A N  G
Sbjct: 2055 TLSIRDVGDQAAASYKCVAFNNAG 2078



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 49/225 (21%), Positives = 83/225 (36%), Gaps = 16/225 (7%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+    + W+ +G  +  + R        +    I      D+GTY C A N+ G +  S
Sbjct: 2654 GNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRS 2713

Query: 3136 VKLE-----CVDKSKGQKPRF---TTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYH 3187
              +E      VD +  + P       H  + EG+  G++    C V+      + IEW+ 
Sbjct: 2714 CTIEIKEPKSVDSTDTRAPGQLIPVKHKFDFEGVPGGKA---RCDVLVKKSDIIDIEWFR 2770

Query: 3188 NGQPMRHSTRIKTV-SDFGFVV-LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKG 3245
                +R   + K + SD G  + L +      D+G Y C  +   G+   R  ++   K 
Sbjct: 2771 GTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHTPAGQTTIRGELHIKEK- 2829

Query: 3246 GVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQD 3290
                  L  D      +    QG +     T +  P   IT  +D
Sbjct: 2830 --QQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKD 2872



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 9/83 (10%)

Query: 799  DPTMRVEWYKDGRPITASSR--ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
            +P   V WY+DG  +  ++R  I S  +  YV  NI  L  EDAG+Y   A +++G AI 
Sbjct: 3409 NPRPHVVWYRDGILLYDTTRMDIRSRGDLHYV--NIYGLTLEDAGNYVCEARSRIGTAIR 3466

Query: 857  TASIRVAARSTVTADLGIPEQRR 879
            + ++ +   S     +G PE+++
Sbjct: 3467 SCTLEIKVPS-----MGGPEEKK 3484



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 4/106 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVA 1102
            P+FL  L   + + EG SA    ++  + +   TVEW+ + + IT+ +R+++        
Sbjct: 3687 PKFLSHLNSLD-VDEGDSAKLTCKMFGKPE--PTVEWFKDDQLITNNDRVRSSVVGNTCT 3743

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHR 1148
            L   +V  +D G Y   A N  G    SA + V  R+SI    I +
Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSAVIVV-NRASITPRIIEK 3788



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 23/60 (38%), Positives = 29/60 (48%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V WF +G  L   SR+   +      L I G+   DAG Y C+A +R G    SC L VK
Sbjct: 4184 VFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSCTLDVK 4243



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 2/72 (2%)

Query: 2519 ELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDA 2578
            ++ E + A +   V   G P+ R +W++N   +   SR  T+ D     L I      D 
Sbjct: 4465 DVTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDGPVHKLAITKATLQDT 4522

Query: 2579 GLYMCKAINRAG 2590
            G+Y C A+N  G
Sbjct: 4523 GVYKCLAVNDNG 4534



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 57/234 (24%), Positives = 89/234 (38%), Gaps = 34/234 (14%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+FI +  +  K+V  +            +P  +V W+ +G  L    R  T        
Sbjct: 4945 PEFIDEEGEYVKVVRSEGVA-NITFTVRGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHY 5003

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLE 3401
            L+I     E++G Y C A +KLG        KC    + ILD Q        + K +   
Sbjct: 5004 LNIFSLTSEDAGTYMCEARSKLG--------KCF--RSCILDVQ-------AVPKEEVDH 5046

Query: 3402 DSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGK 3461
              +V+             PV T  + + +   EG N  FE  +     P   VEWY    
Sbjct: 5047 GQIVK-------------PVITRKIRDAQG-EEGSNIRFEIHVKSHPPP--HVEWYRGSI 5090

Query: 3462 SLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
             L  G +++     G   L I+    +D+G Y   A N  G + + A + V+ K
Sbjct: 5091 KLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDK 5144



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG+       ++  P P+  V+WY  GK+L +      S       + I +   E SG Y
Sbjct: 5456 EGREVELSTVVKGLPRPS--VKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRY 5513

Query: 1918 TCKAINNLGQAVSSIRLNVQSK 1939
             C+A N+ G A     LN+Q++
Sbjct: 5514 RCEATNSNGTAHRDFVLNIQAQ 5535



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 4/97 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR-TFCDFGFV 3478
            P     L  IE    GE A F+  +T    P  +V+WY     +   +R+  T    G  
Sbjct: 5640 PEINEKLKKIEAFEGGE-ARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMA 5696

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
             L I     ED G Y C A N YGE  +   + V  K
Sbjct: 5697 SLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 8/107 (7%)

Query: 1036 EVKITQ---KPRFLGPLKGTNKIVEGQSA-HFEARVEPQSDLTMTVEWYFNGKQITSANR 1091
            EVK+     KP  +  ++  + + E  ++ H E   +P+ +    +EW+     I    R
Sbjct: 816  EVKVEDRSLKPEVITSMRDCDCVEEETASFHCEFSGKPEPE----IEWFCGPNPIVPGGR 871

Query: 1092 IQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
                 +    +L I+ ++ ED+G Y  VA NAAG+    A + V  +
Sbjct: 872  FHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTRAELKVNEK 918



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 3/92 (3%)

Query: 2499 EEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR 2558
            E   ++ + P F   L  P E+ EG        V   G P    +W+ + V +K   RF+
Sbjct: 1012 EALQKKGDTPTFMSKLE-PIEITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFK 1068

Query: 2559 TTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             ++D     L +     +D G+Y C   N  G
Sbjct: 1069 ASYDGNVSALTVKEAELDDDGVYKCVVTNNFG 1100



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 1302 REDITVMQA---PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHR 1358
            + D+TV++    P+  + + ++ TVEG   +   ++         +EW+     I  G R
Sbjct: 1105 KADVTVLKKHLRPEVLQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGR 1162

Query: 1359 FRPAYEFDYVALDLL--SVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            F+   + +  +  L    V  +D+G   C ATN  G+ V    L V  K
Sbjct: 1163 FKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 6/98 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL---TTMHDFGY 1767
            P     M D+R  E   A+F  ++     PK  +EW      I    R    T   +  Y
Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAF--PKPEIEWYLGATKITDGGRFKIKTDKENCSY 1174

Query: 1768 VALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            + L +  V  +D+GT  C A N  G+ V  + L V+ K
Sbjct: 1175 I-LFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 6/95 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF---TSIFRFGY 693
            P+ +  +  V  +EGGK +F  +I+    P  +IEW      I    RF   T      Y
Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSY 1174

Query: 694  ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            I L +  + + D+G   C A +A G    +A L V
Sbjct: 1175 I-LFIDDVKLDDAGTVKCSATNAAGKTVVRADLEV 1208



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 6/125 (4%)

Query: 3409 DTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSR 3468
            D  V++E   AP     L   E++ EG++     +++   +P L  EW  N + L    R
Sbjct: 1304 DVEVKQEVMIAPEIRQQLQ-AEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDR 1360

Query: 3469 FRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK--RNIILESQLP- 3525
            F+T  D     L I      D+  Y     N+ GE  ++A +KV  K  +  +LE     
Sbjct: 1361 FKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDV 1420

Query: 3526 KGMEG 3530
            KG+EG
Sbjct: 1421 KGVEG 1425



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 29/107 (27%), Positives = 42/107 (39%), Gaps = 4/107 (3%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM- 4164
            K   P V   + D   VE G+ A F  +++G+P P + W      I +G RYK + D   
Sbjct: 1407 KCTKPEVLEKMKDVKGVE-GDEATFNVKLSGYPSPDIEWYYGTTRIRDGGRYKFSRDDQK 1465

Query: 4165 YHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLK 4211
            Y   I      D G  + I             L+V  R  DY  + +
Sbjct: 1466 YSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKER--DYAPIFE 1510



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            PE      D+   E   A F  +L      S  +EW++    +  G R K   D     L
Sbjct: 1411 PEVLEKMKDVKGVEGDEATFNVKLSGY--PSPDIEWYYGTTRIRDGGRYKFSRDDQKYSL 1468

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             I  +  +D G Y C A+N  G+ T   +L+VK R
Sbjct: 1469 TIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKER 1503



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP+  +QL    +++E       C ++  PDP+   EW  + K ++      +S D   
Sbjct: 1606 EAPKLTSQLRS-ARITESDDFELACDVKGTPDPSY--EWLKDDKPVKFDRHLSSSFDGKK 1662

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV---QSKESIIRDSQHESALE 1953
              L+   V   D G YT    N  G   SS  L++   +SK  I+   +    +E
Sbjct: 1663 CTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSKPEILETMKDAEGIE 1717



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFN-NKPLPSGTRYKSTHDFSYVSLD 2834
            F + L  I   EG+N  F C V    +P+  + W+ N N+ +P G R ++T D     L 
Sbjct: 1905 FTTTLKPIDVTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDG-RSRTTFDGETYKLI 1961

Query: 2835 ITHTYEEDSGIYTCKATNSKGSA 2857
            +     +D+G Y C A+N  G A
Sbjct: 1962 LQDIKIKDAGQYECIASNPIGKA 1984



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 3699 VEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS--RVHTLNDFGFIALD 3756
            +E    + + EG    FD R+   G PT  ++WF+       G   R+ +  + G  +L 
Sbjct: 2532 IEKPAGLVIVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLV 2589

Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            +  +     G Y   A+N+ G A     +T + +
Sbjct: 2590 VSKVQLDQTGHYRIVASNEHGKAQALLDLTVNER 2623



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 4/77 (5%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSLDITHTYE 2840
            +V  EG++  F+  +     PT ++EWF+ ++ L  G +Y+  S  +    SL ++    
Sbjct: 2538 LVIVEGNDSRFDVRIRGH--PTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQL 2595

Query: 2841 EDSGIYTCKATNSKGSA 2857
            + +G Y   A+N  G A
Sbjct: 2596 DQTGHYRIVASNEHGKA 2612



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 21/66 (31%), Positives = 31/66 (46%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   +EWF     L  G R +      L TL I++L  +D+G Y   ATN  G   S   
Sbjct: 3312 PRPTVEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVD 3371

Query: 2732 IKIEDR 2737
            + +++R
Sbjct: 3372 LTVKER 3377



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 5/84 (5%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +++ V E Q  + +  ++    P+L V W ++G  ++ + R+       +  L +    P
Sbjct: 3595 QELNVPEGQEINMD--VVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAP 3652

Query: 1778 EDSGTYTCRAINELGEAVTSSTLF 1801
            EDSG Y C  ++ LG   TSS  F
Sbjct: 3653 EDSGLYKCEGVSTLG---TSSKTF 3673



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 2920 EHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYER 2979
            E  + EGQ ++++  V  K+ P L++ WY +G++L+   R  + S      L +      
Sbjct: 3596 ELNVPEGQEINMD--VVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPE 3653

Query: 2980 DSGIYTCKAYNKRG 2993
            DSG+Y C+  +  G
Sbjct: 3654 DSGLYKCEGVSTLG 3667



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 2/92 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+F +  + L + E  SA   C++    + +  VEWF + + +    RV++        L
Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTL 3744

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
                V  +D G Y C ATN+ G  + S  + V
Sbjct: 3745 IFETVNIQDRGAYRCTATNQEGSTSSSAVIVV 3776



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 2/89 (2%)

Query: 1848 TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDIL 1907
            +++  P  + EG        +   P P   VEW+ +G++L + +         +  LD+L
Sbjct: 3884 SEMPEPIVVREGCEVSMMANVRGKPAPT--VEWFKDGQLLSNTNNLHLRARGEYFNLDLL 3941

Query: 1908 TVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
                 DSG Y   A N+LG A     LNV
Sbjct: 3942 KTTQADSGTYKFVATNDLGSAYRIFNLNV 3970



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 3/90 (3%)

Query: 2501 PDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTT 2560
            P  ++  PIF   L+ P  + EG +  + A V  V  PS   +WY +   +    R RT 
Sbjct: 3975 PKEKWSSPIFVTELS-PLSVTEGDYTKFVAHVSGVPLPS--IQWYKDDNPISSNHRIRTF 4031

Query: 2561 HDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             D   V L I  +   D G Y     N +G
Sbjct: 4032 FDGHVVKLLIGQITLEDQGQYKVVLKNESG 4061



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F+  L  ++  EG    F   +   G P   I+W K+   I ++ R  + F    + L
Sbjct: 3982 PIFVTELSPLSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKL 4039

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +  + ++D G+Y     + +G A + A L V
Sbjct: 4040 LIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 21/68 (30%), Positives = 34/68 (50%)

Query: 797  VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
            + +P   V W+KDG  +  +SR+          LNI  L  +DAG+Y   A ++LG    
Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236

Query: 857  TASIRVAA 864
            + ++ V A
Sbjct: 4237 SCTLDVKA 4244



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 3/87 (3%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK---LTYDGMYHFDIPKTRQYD 4176
            VT  EG   +   R+TG+P P V W      I +G RYK   +  +G+Y   I   +  D
Sbjct: 4266 VTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLED 4325

Query: 4177 TGKIEVIXXXXXXXXXXXXXLKVIPRH 4203
            +G    +             L V  +H
Sbjct: 4326 SGSYRAVASNNLGEATTLAELTVKGKH 4352



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 4/111 (3%)

Query: 643  LKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLN 702
            L+ V  +EG ++   T ++  G P   ++W K G+ +  S   T         + + S  
Sbjct: 5449 LEQVVGVEGREVELSTVVK--GLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAK 5506

Query: 703  IQDSGEYTCRAVSATGVAETKAVLHVTPRATIER--TSQHPETLQYIQQLE 751
             + SG Y C A ++ G A    VL++  +   E+         LQ+I  LE
Sbjct: 5507 HEHSGRYRCEATNSNGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDILE 5557



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 4/87 (4%)

Query: 2505 FEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTT-HDF 2563
            + KP   + L    E +EG  A ++  V   G P  R +WY    ++   +R+ +T    
Sbjct: 5637 YSKPEINEKLK-KIEAFEGGEARFDLLVT--GFPPPRVDWYRGTTKITDCNRYSSTLTSD 5693

Query: 2564 GFVTLDINSVVANDAGLYMCKAINRAG 2590
            G  +L I  +   D GLY C A+N  G
Sbjct: 5694 GMASLTIRKIRQEDGGLYGCVAVNEYG 5720



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 19/75 (25%), Positives = 36/75 (48%)

Query: 2384 NIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            +++ I+  +    + RL   G+P  +V W+++   + D+ ++          ++I     
Sbjct: 385  DLEPIEVKEDQAVNVRLTVTGNPKPEVTWYKDGTQLHDTKKLKLKATGDVHELSIPKAST 444

Query: 2444 EDEGVYMCRASNLLG 2458
             DEG Y C ASN LG
Sbjct: 445  NDEGQYFCEASNPLG 459



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 3/100 (3%)

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            +E + Q P F   +K I V   + A     +   G PK +V W ++ VP+  +  +    
Sbjct: 625  NEKVVQ-PEFDKEVKPIEVKHGEEATTSLEI--KGKPKPKVTWYKDLVPLLETRSIQLKS 681

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
                  L +    P+D G Y C A N+ G A  S  + V+
Sbjct: 682  VGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVK 721



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 19/55 (34%), Positives = 25/55 (45%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P    EW+     +  G RF  T +    +L I+ +   DAG Y C A N AG
Sbjct: 851  GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAG 905



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 3/100 (3%)

Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028
            K   P F+++++    + E +  +  C +   G P  +V+WF +   +    RF   YD 
Sbjct: 1017 KGDTPTFMSKLEP-IEITEGDDFQLSCNVT--GRPQPEVQWFRDEVLIKPSRRFKASYDG 1073

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
               A+       +D G Y C  TN +G   +KA +    K
Sbjct: 1074 NVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKK 1113



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P   Q LQ  +++ EG      C++    +PTL  EW +N +L+ D+ R     D    +
Sbjct: 1315 PEIRQQLQ-AEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGT 1371

Query: 2436 MTISHVRDEDEGVYMCRASNLLGE 2459
            +TI +V   D   Y     N  GE
Sbjct: 1372 LTIRNVTLADAVPYKVVVRNDAGE 1395



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 5/93 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P+  +EW  N ++L    RFK   D    TL + +V   D+  Y     N  GE  +S+ 
Sbjct: 1342 PEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAK 1401

Query: 3001 V----YCTSKDNLIERTQHPKGTEGLEKIQNLE 3029
            +     CT K  ++E+ +  KG EG E   N++
Sbjct: 1402 LKVIRKCT-KPEVLEKMKDVKGVEGDEATFNVK 1433



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 22/67 (32%), Positives = 31/67 (46%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P   + W+ N K L  G   +     +Y +L I  + EED+G Y C A N  GSA     
Sbjct: 1536 PKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFE 1595

Query: 2863 LRCTGDK 2869
            ++  G K
Sbjct: 1596 VQVEGVK 1602



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            +AP F   L  +   EG    L   +   G     ++W  +  P+  GHR RP ++    
Sbjct: 2431 EAPSFKSQLQPVILEEGGTGVLVGEV--AGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTC 2488

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +        D G+Y C   NQ GEA +   + V
Sbjct: 2489 KVIFREALIGDGGMYECIIKNQCGEASSKALVGV 2522



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 20/72 (27%), Positives = 34/72 (47%)

Query: 1337 VGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
            +G+    V W+ +G  +    R       D    ++  V PED+G Y C+A N+LG +  
Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFR 2712

Query: 1397 SCALRVIAKKDL 1408
            SC + +   K +
Sbjct: 2713 SCTIEIKEPKSV 2724



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 5/86 (5%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR--TTHDFG 2564
            +P+ T  L    + +EG+ A ++  V   G PS   EW+     +  G R++  +  + G
Sbjct: 3030 RPLITHKLHD-MKAYEGKEARFDIEVT--GHPSPTVEWFKGPSGISEGRRYQLMSNEEQG 3086

Query: 2565 FVTLDINSVVANDAGLYMCKAINRAG 2590
              +L ++ + A+D G+Y C A N AG
Sbjct: 3087 KHSLIVSDLNADDDGIYKCVAQNLAG 3112



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 10/131 (7%)

Query: 1541 DIVRSTQNEAGLEQIQVLEDRSKYHR------TDMVDEVTTQAPICTTSLKNVEIKEGQR 1594
            D++++TQ ++G  +     D    +R      T +  +    +PI  T L  + + EG  
Sbjct: 3939 DLLKTTQADSGTYKFVATNDLGSAYRIFNLNVTAIAPKEKWSSPIFVTELSPLSVTEGDY 3998

Query: 1595 AHFERRLIPVSDATL-KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCR 1653
              F   +  VS   L  ++WY ++ P+ S  R     +   V L I     ED G Y   
Sbjct: 3999 TKF---VAHVSGVPLPSIQWYKDDNPISSNHRIRTFFDGHVVKLLIGQITLEDQGQYKVV 4055

Query: 1654 AINALGEAVTS 1664
              N  G A +S
Sbjct: 4056 LKNESGSATSS 4066



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 2/90 (2%)

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
            GP  ++ G   +    I   P P+  V WY +G  + +    +  +      L IL    
Sbjct: 5157 GPITITRGNQLNLNVTIRGKPKPS--VVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKS 5214

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            E +G Y+C+A + LG   +   + +Q+ E+
Sbjct: 5215 EHAGTYSCEATSKLGNTSAKFDVQIQAPEA 5244



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 6/100 (6%)

Query: 3552 AESGNPPEFTTTPSDLILSENSSAHF--ECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI 3609
            AE    P FT     + + E  +  F  E   +PV      VEW+ + +P+    R++T 
Sbjct: 5538 AEQWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVPV----VEWYRDDRPVTRDHRLRTY 5593

Query: 3610 NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +D   VIL +      DAG++ C   N  G    S  L V
Sbjct: 5594 SDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/70 (34%), Positives = 33/70 (47%)

Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261
            E  G P   VEW+ + R VT   R +TY D   V L +     +D G +     N LG+ 
Sbjct: 5566 EITGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTV 5625

Query: 1262 HTSAIVRVIE 1271
             +SA + V E
Sbjct: 5626 ASSASLNVNE 5635



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF-GYVALTIKSVTVHDAGH 981
            E G A F+  +E     T  VEW +    + +S +     +  G  +L IK +T  DAG 
Sbjct: 4    ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61

Query: 982  YTCRAYNAIGQATTSANLTIVTKK 1005
            Y C A N  GQ +   +L++  K+
Sbjct: 62   YKCVATNDAGQTSLRGDLSVKEKQ 85



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 3/78 (3%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSLDITHTYEEDSGI 2845
            E     F+  +E    PT  +EW+     + S  ++K   D     SL I    ++D+G 
Sbjct: 4    ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61

Query: 2846 YTCKATNSKGSATTSGSL 2863
            Y C ATN  G  +  G L
Sbjct: 62   YKCVATNDAGQTSLRGDL 79



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 6/129 (4%)

Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLH-KNR 4021
            DL   +K+  P+   + Q    + E E+   +  L   G P  +V W+ +GKPL   K+ 
Sbjct: 78   DLSVKEKQIAPQIKEKEQEPIEVFEGESVNLD--LTITGKPKPEVVWYKDGKPLRKTKSI 135

Query: 4022 FTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD--ETKAVIKTTGKPGIVYDSQLPK 4079
                 D  Y  ++     P DSG+Y C A N  G    +    +K  GK   V     P 
Sbjct: 136  DLKSTDDSYF-LSIPKATPNDSGKYKCEAKNKIGTSARDFDVNVKVKGKAPTVTSELKPD 194

Query: 4080 HMKSIEKIR 4088
             ++  E+ +
Sbjct: 195  KVQEGEQYK 203



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 28/112 (25%), Positives = 43/112 (38%), Gaps = 2/112 (1%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P     LK     EG +  F   +   G P   I W K+GQ I+A  R    F     +L
Sbjct: 185 PTVTSELKPDKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVKDSFDGTTSTL 242

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQ 748
            +  +   D G Y     +  G   + A L VTP+       +  E ++ ++
Sbjct: 243 LIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVESVE 294



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 7/96 (7%)

Query: 769 RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI--TASSRITSIFNFG 826
           +P+F + ++ + E++ G  A    ++     P  +V WYKD  P+  T S ++ S+ +  
Sbjct: 630 QPEFDKEVKPI-EVKHGEEATTSLEIK--GKPKPKVTWYKDLVPLLETRSIQLKSVGDEH 686

Query: 827 YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             +L I++   +D G Y   A NK G A  +  I+V
Sbjct: 687 --TLEIINATPDDEGKYKCEATNKAGTAFRSFDIKV 720



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 6/94 (6%)

Query: 3426 LSNIENLR--EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFG--FVILE 3481
            L  ++++R  EG  A+F  ++     P  ++EWY     +  G RF+   D      IL 
Sbjct: 1120 LQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSYILF 1177

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
            I     +D+G   C A N  G+ V  A ++V+ K
Sbjct: 1178 IDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 52/225 (23%), Positives = 87/225 (38%), Gaps = 40/225 (17%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            + + V I P  + +    E+V EG      CK+    +  L  EW KN + ++   RF+ 
Sbjct: 1307 VKQEVMIAPE-IRQQLQAEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKT 1363

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555
              D               +G  T R V L   D V  ++  R+    V S+       ++
Sbjct: 1364 RFD-------------GQTGTLTIRNVTLA--DAVPYKVVVRNDAGEVSSSA------KL 1402

Query: 1556 QVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYH 1615
            +V+   +K              P     +K+V+  EG  A F  +L         +EWY+
Sbjct: 1403 KVIRKCTK--------------PEVLEKMKDVKGVEGDEATFNVKLSGYPSPD--IEWYY 1446

Query: 1616 NNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
                ++ G R+  + +    +L I     +D GTY C A N  G+
Sbjct: 1447 GTTRIRDGGRYKFSRDDQKYSLTIKDLNLQDIGTYKCIASNEAGK 1491



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 21/65 (32%), Positives = 30/65 (46%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   V W+ NGK L+ G          +  L I  +  ED+G Y C A N+ G A     
Sbjct: 1536 PKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFE 1595

Query: 3510 MKVQG 3514
            ++V+G
Sbjct: 1596 VQVEG 1600



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F T  K I+ V EG++  F C++    + +  V W++N   +    R R   D     
Sbjct: 1903 PSFTTTLKPID-VTEGENHTFICRVHARPEPS--VTWYRNKNEIVPDGRSRTTFDGETYK 1959

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            L + D+  +D+G Y C A N +G    +  +T
Sbjct: 1960 LILQDIKIKDAGQYECIASNPIGKAFCTAEMT 1991



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 52/221 (23%), Positives = 82/221 (37%), Gaps = 39/221 (17%)

Query: 644  KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI 703
            K+    EGG    E ++  V  PT  +EW      +    RF       Y +L +  +  
Sbjct: 2006 KTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGD 2063

Query: 704  QDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIE 763
            Q +  Y C A +  G          T RA +  T +     +Y  + ED+         E
Sbjct: 2064 QAAASYKCVAFNNAG--------RTTYRADLVITER-----EYAPEFEDFD--------E 2102

Query: 764  EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIF 823
            ++ + R              EG+NA     +T  + P+  VEWYK    + +  +I    
Sbjct: 2103 KRIAVR--------------EGQNAI--TNMTIRARPSPDVEWYKGDTLLMSDRKIDLKT 2146

Query: 824  NFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
              G   L I     +DAG+Y  +A N +G       + V A
Sbjct: 2147 IGGLYYLEIRKATLDDAGTYICKATNSIGSTSRRIIVDVEA 2187



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAG 3628
            +SE  +A  E ++  V   +  VEW+H    +L G R +   +  +  L I  V  + A 
Sbjct: 2010 VSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAA 2067

Query: 3629 LYTCKATNRHGEATVSCKLQVKGRQ 3653
             Y C A N  G  T    L +  R+
Sbjct: 2068 SYKCVAFNNAGRTTYRADLVITERE 2092



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK--TYYDFGFVALDIIHATSAD 1246
            + EG +   + R+   G PT  VEWF+    +T G +++  +  + G  +L +       
Sbjct: 2540 IVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597

Query: 1247 TGEYTVRAVNHLGSAHTSAIVRVIER 1272
            TG Y + A N  G A     + V ER
Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTVNER 2623



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 21/55 (38%), Positives = 27/55 (49%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P  + +W  NG  ++   R RT +D     L I  V  +DAG Y C A N AG
Sbjct: 2960 GKPKPQIKWTKNGKPVESDGRLRTDYDGIVAYLSIWQVSHDDAGTYECIASNAAG 3014



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN--DFGF 3752
            P  T ++ D +   EG    FD  +E  G P+  ++WF      + G R   ++  + G 
Sbjct: 3031 PLITHKLHD-MKAYEGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGK 3087

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
             +L +  + A D G Y C A N  G A+T A +   A+
Sbjct: 3088 HSLIVSDLNADDDGIYKCVAQNLAGKASTRAMLDVIAR 3125



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 3837 KSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV--YDMGFVSLDILYV 3894
            K H ++  EG      +E    P   +EW++    +  G RY+ +   + G  SL +  +
Sbjct: 3036 KLHDMKAYEGKEARFDIEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDL 3095

Query: 3895 YAEDSGEYICRAVNDFGEDFTKATI 3919
             A+D G Y C A N  G+  T+A +
Sbjct: 3096 NADDDGIYKCVAQNLAGKASTRAML 3120



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 52/252 (20%), Positives = 98/252 (38%), Gaps = 23/252 (9%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G P   ++WF +G+      R+   +      L I ++   D G Y C A++  G ++ T
Sbjct: 3156 GRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSYKCVASSTNGRSSRT 3215

Query: 3783 AKITCSAKRDI------VLESQLP--QGMSGEKIKELERGRISDAP-----KEEPIVSTP 3829
              ++    +           S+L   + + GEK K +        P     K++  +   
Sbjct: 3216 FDLSVKVPKPKDKWSLPAFSSKLRPLETLEGEKTKFVVNVSGEPIPTVEWFKDDTPIKHE 3275

Query: 3830 PKFITQIKSHT--VEESEGVRFEC---RVEPKED--PKLRIEWYRNGKLLPSGHRYRTVY 3882
             +F T        +   +   FEC   R+E      P+  +EW+     L  G RYR   
Sbjct: 3276 DRFRTYFDGRVCMLVFRKTDSFECSEARLEAHVAGVPRPTVEWFLGSAKLCDGERYRLEQ 3335

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKL---PDIILQNQVPRGMKR 3939
                 +L I  ++ ED+G Y   A N+ G   +   ++ K+    P+ + +  V   + +
Sbjct: 3336 TDNLYTLVISNLHMEDTGPYKIIATNEHGSTGSVVDLTVKERLFGPEFLEEEGVWNKVAK 3395

Query: 3940 SEALTQMEATIK 3951
            +     +  T+K
Sbjct: 3396 AGGFVNISFTLK 3407



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 23/85 (27%), Positives = 34/85 (40%)

Query: 777  QDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLR 836
            +D  EL           +   S P + V WYKDG  +  + RI       +  L I    
Sbjct: 3592 EDRQELNVPEGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAA 3651

Query: 837  AEDAGSYTVRAVNKLGEAISTASIR 861
             ED+G Y    V+ LG +  T  ++
Sbjct: 3652 PEDSGLYKCEGVSTLGTSSKTFDVK 3676



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 4/109 (3%)

Query: 1965 KRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGH 2024
            K  V D S V   P+F   + + +V EG    L   +    +PT  VEW+ + + +    
Sbjct: 3676 KAGVPDGSRVT--PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNND 3731

Query: 2025 RFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
            R +++       L       +D G Y C ATN  G   +++ + V+  S
Sbjct: 3732 RVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGSTSSSAVIVVNRAS 3780



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 6/106 (5%)

Query: 1838 VAVNQA---PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
            + VN+A   PR I +      + +G  A +  R+E +P P  +V W+     + S  RY 
Sbjct: 3774 IVVNRASITPRIIEKPRDVDAV-DGTDAKFTVRVEGFPQP--KVTWFHESTKIVSRGRYE 3830

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             S      +L I  V     G Y C A N+ G+  +   L+V  ++
Sbjct: 3831 ISRVGDLYSLVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQD 3876



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/93 (25%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            +P F   L  +   EG        +   G     ++W+ +  PI + HR R  ++   V 
Sbjct: 3981 SPIFVTELSPLSVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVK 4038

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L +  +  ED G Y     N+ G A +S  L V
Sbjct: 4039 LLIGQITLEDQGQYKVVLKNESGSATSSAKLSV 4071



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 5/148 (3%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRT-DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERR 1600
            I ++T  + G+ +   + D      T D+        P     L+ V    G  A F  R
Sbjct: 4514 ITKATLQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGEASFSVR 4573

Query: 1601 LIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            +        K+ WY +   L +  RF  +       L I +   +DSGTY C   NA+G+
Sbjct: 4574 VKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGK 4631

Query: 1661 AVTSGIAIVHSKK--SIYLESQHEGALP 1686
                   +V +++    + E + +GA+P
Sbjct: 4632 ETCRSQLVVEAEEFAPFFPEDEGQGAVP 4659



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 33/130 (25%), Positives = 58/130 (44%), Gaps = 11/130 (8%)

Query: 1266 IVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQA---PQFSRALHNIET 1322
            ++R+I R   + D      + +  +L D    T     D++V +A   P+ +  + +I+ 
Sbjct: 4807 VIRLIVRRTTLEDA----GLYRCTILNDLG--TASSMADLSVNRALTKPEVAEKMTDIDA 4860

Query: 1323 VEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGV 1382
            VEGT V LE  +   G    +VEWF +   +    R+  +   D   L + +    D+G 
Sbjct: 4861 VEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCTTNDTGP 4918

Query: 1383 YTCQATNQLG 1392
            Y    TN+ G
Sbjct: 4919 YKVIGTNECG 4928



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 3/100 (3%)

Query: 767  SQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG 826
            +QRP+    +++L     G  A FE  +T  + P  ++ WYKD   + +  R T     G
Sbjct: 5342 TQRPRLSDNMKELFATVGGE-ARFE--VTMKATPKPKICWYKDEITLRSRDRYTMKEEDG 5398

Query: 827  YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
              +L I  ++  D+G+Y   A NK G+      + V  ++
Sbjct: 5399 IYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKT 5438



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 3/99 (3%)

Query: 906  TQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
            TQ+P     +K+  +   GG A FE  ++       ++ W KD   + +  R T     G
Sbjct: 5342 TQRPRLSDNMKELFATV-GGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDG 5398

Query: 966  YVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
               L IK V + D+G Y   A N  G+ T    L ++ K
Sbjct: 5399 IYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK 5437



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 29/98 (29%), Positives = 39/98 (39%), Gaps = 2/98 (2%)

Query: 1575 TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGF 1634
            TQ P  + ++K +    G  A FE  +        K+ WY +   L+S  R+T     G 
Sbjct: 5342 TQRPRLSDNMKELFATVGGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGI 5399

Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSK 1672
              L I      DSGTY   A N  G+    G   V  K
Sbjct: 5400 YTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK 5437



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 5/110 (4%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S  + V E    P   + E       FEG  A F+  V     P  R+++Y     +   
Sbjct: 5628 SASLNVNEGYSKPE--INEKLKKIEAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDC 5683

Query: 2289 ARFHITFDF-GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             R+  T    G  SL I+    ED G Y   A+N  G  TS + + V  K
Sbjct: 5684 NRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEK 5733



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 1/51 (1%)

Query: 1077 VEWYFNGKQITSANRIQ-TYHDFGYVALDIASVRAEDSGVYTVVARNAAGE 1126
            V+WY    +IT  NR   T    G  +L I  +R ED G+Y  VA N  GE
Sbjct: 5671 VDWYRGTTKITDCNRYSSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGE 5721



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%)

Query: 1546 TQNEAGLEQIQVLEDRSKYH-RTDM-VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIP 1603
            T+++AG  +     D  +   R D+ V E      I     + +E+ EG+  + +  L  
Sbjct: 55   TKDDAGAYKCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGESVNLD--LTI 112

Query: 1604 VSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
                  +V WY + KPL+        +      L I    P DSG Y C A N +G
Sbjct: 113  TGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIG 168



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 9/98 (9%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL--TTGARLKSTFDF- 2697
            AP F     + D L +GQ V +   V  R  P  +I W K+G  L  T   ++K   D  
Sbjct: 921  APEFEDWKDTIDAL-DGQDVNISTWV--RGKPKPEIVWLKDGEELRNTMHVQIKCYGDLH 977

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            GLV   ++    +D+G+YTC+A N  G      +I +E
Sbjct: 978  GLVLYKVSP---EDAGMYTCRAKNNAGIVSKDVTITVE 1012



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +GQ  +    +   P P   + W  +G+ L++    +         L +  V  ED+G Y
Sbjct: 935  DGQDVNISTWVRGKPKPE--IVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGMY 992

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
            TC+A NN G     + + V++ +         S LE I+  E D
Sbjct: 993  TCRAKNNAGIVSKDVTITVEALQKKGDTPTFMSKLEPIEITEGD 1036



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 8/131 (6%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHD---FSYVSL 2833
            +  ++++   EG   +F   ++    P  +IEW+     +  G R+K   D    SY+ L
Sbjct: 1120 LQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSYI-L 1176

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
             I     +D+G   C ATN+ G       L    +KN+       QG+  ++   +A   
Sbjct: 1177 FIDDVKLDDAGTVKCSATNAAGKTVVRADLE-VEEKNVAPSFHGRQGRLRVKEGREASVY 1235

Query: 2894 RLAKGR-RPSV 2903
                G+ +PSV
Sbjct: 1236 FEISGKPKPSV 1246



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFV 1635
            P    ++K+ E  E  +A F+ ++     A  +VEWYH +  +  G R+  T+    G  
Sbjct: 1704 PEILETMKDAEGIETGKAKFDVKIKAYPKA--EVEWYHRSARIYDGGRYCLTQDEEDGTY 1761

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGE 1660
            ++ I     ED GTY   A N +G+
Sbjct: 1762 SVTINDLRLEDCGTYKIVAFNDIGK 1786



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)

Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDDSGIYTCKATNLL 2723
            V+ +  P  ++EW+     +  G R   T D   G  +++IN LR +D G Y   A N +
Sbjct: 1725 VKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDI 1784

Query: 2724 GEAVSTASIKIEDR 2737
            G+    A + ++++
Sbjct: 1785 GKTSERAELTVKEK 1798



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 36/143 (25%), Positives = 59/143 (41%), Gaps = 13/143 (9%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC--DFGFVILEISPTYPEDSG 3491
            EG ++ F+ R+     P  +VEW++  + L  G ++R     + G   L +S    + +G
Sbjct: 2542 EGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTG 2599

Query: 3492 EYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPE 3551
             Y   A N +G+A     + V     +     L    +G   K+    G+     TL   
Sbjct: 2600 HYRIVASNEHGKAQALLDLTV--NERLYAPEFLED--DGEWSKVVRKGGFVNITFTL--- 2652

Query: 3552 AESGNPPEFTTTPSDLILSENSS 3574
               GNP  F T   D IL  ++S
Sbjct: 2653 --MGNPRPFVTWYKDGILLYDTS 2673



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 45/204 (22%), Positives = 77/204 (37%), Gaps = 30/204 (14%)

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
            +G+P   + W+ +G      SR    +       +I ++   D G Y C A N+ GS+  
Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFR 2712

Query: 3782 TAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTV 3841
            +  I                     +IKE +    +D      ++    KF         
Sbjct: 2713 SCTI---------------------EIKEPKSVDSTDTRAPGQLIPVKHKF-------DF 2744

Query: 3842 EESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY--DMGFVSLDILYVYAEDS 3899
            E   G +  C V  K+   + IEW+R   +L  G +Y+ +   D   +SL +  V  ED+
Sbjct: 2745 EGVPGGKARCDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDA 2804

Query: 3900 GEYICRAVNDFGEDFTKATISCKK 3923
            G Y C      G+   +  +  K+
Sbjct: 2805 GTYRCVVHTPAGQTTIRGELHIKE 2828



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 18/57 (31%), Positives = 30/57 (52%)

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            + WY +G +L   SR  + S       ++  V   D+G Y C+A+N+ G +F S T+
Sbjct: 2660 VTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTI 2716



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 23/93 (24%), Positives = 38/93 (40%)

Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022
            +L+  +K+Q P F+ +  SQ      +  +        G P   + W+ +G+PL    R 
Sbjct: 2823 ELHIKEKQQAPLFLDEKVSQEKFSLPQGQEMNKSFTVTGSPTPHITWYKDGEPLDDTRRI 2882

Query: 4023 TPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
                      +    + PED+G Y C A N  G
Sbjct: 2883 DIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIG 2915



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 1455 NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDS 1514
            NV EGQ ++ +  ++  +   L+V W+K+G+ +    R        +  L I     EDS
Sbjct: 3598 NVPEGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDS 3655

Query: 1515 GIYTCRAVNLVGT 1527
            G+Y C  V+ +GT
Sbjct: 3656 GLYKCEGVSTLGT 3668



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F + LR +  V E ++A F C+V     P  RI+++ N + +   +R   + D     
Sbjct: 4455 PGFKSALR-SLDVTEDESAEFRCEVSG--SPAPRIQWFMNDQPVSRDSRIITSSDGPVHK 4511

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVT 2335
            L I     +D G Y   A+N  G  TS   + V+
Sbjct: 4512 LAITKATLQDTGVYKCLAVNDNGSATSTADLNVS 4545



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 20/67 (29%), Positives = 33/67 (49%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   V W+ +G K+      +      +  L IL+   E++G Y C AT+KLG  S K +
Sbjct: 5177 PKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAKFD 5236

Query: 3372 LKCTSKE 3378
            ++  + E
Sbjct: 5237 VQIQAPE 5243



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 2/95 (2%)

Query: 1454 ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAED 1513
            +N  EG  V F CK+    +   ++EW ++G  +    R    +D  +  L I +    D
Sbjct: 5258 QNAREGDVVKFSCKVTGYPEP--EIEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHAD 5315

Query: 1514 SGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
            SG+Y C   N  G    S  L     T   R + N
Sbjct: 5316 SGMYKCTLKNNSGWASSSAELVVGGKTQRPRLSDN 5350



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 3571 ENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLY 3630
            E     F C++    +    +EW  +G  + +  RV T  D     L I      D+G+Y
Sbjct: 5262 EGDVVKFSCKVTGYPEPE--IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMY 5319

Query: 3631 TCKATNRHGEATVSCKLQVKGR 3652
             C   N  G A+ S +L V G+
Sbjct: 5320 KCTLKNNSGWASSSAELVVGGK 5341



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714
            VEG+ V L   V+    P++K  W+K G  L T   L  +       + I S +++ SG 
Sbjct: 5455 VEGREVELSTVVKGLPRPSVK--WYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGR 5512

Query: 2715 YTCKATNLLGEA 2726
            Y C+ATN  G A
Sbjct: 5513 YRCEATNSNGTA 5524



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 12/127 (9%)

Query: 2907 EYPKPEWIIPIAA---EH-QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            + P  +W+ P      +H  ++EG      G++     P   +EWY + + + +  R + 
Sbjct: 5535 QVPAEQWVAPAFTAPLQHIDILEGDTTRFIGEITGVPVP--VVEWYRDDRPVTRDHRLRT 5592

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022
             SD   V L L      D+G++ C   N  G   +S+++      N+ E    P+  E L
Sbjct: 5593 YSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASL------NVNEGYSKPEINEKL 5646

Query: 3023 EKIQNLE 3029
            +KI+  E
Sbjct: 5647 KKIEAFE 5653



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 1577 APICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA 1636
            AP  T  L++++I EG    F   +  V      VEWY +++P+    R    ++   V 
Sbjct: 5543 APAFTAPLQHIDILEGDTTRFIGEITGVPVPV--VEWYRDDRPVTRDHRLRTYSDGRVVI 5600

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            L +      D+G + C   N LG   +S
Sbjct: 5601 LLLRQTNISDAGVFKCVLRNDLGTVASS 5628



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 23/92 (25%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F  PL+ +  +EG    F   I   G P   +EW ++ + +    R  +      + L
Sbjct: 5544 PAFTAPLQHIDILEGDTTRFIGEI--TGVPVPVVEWYRDDRPVTRDHRLRTYSDGRVVIL 5601

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +   NI D+G + C   +  G   + A L+V
Sbjct: 5602 LLRQTNISDAGVFKCVLRNDLGTVASSASLNV 5633



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 4/92 (4%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKST-HDFSYVSLDITHT 2838
            L  I   EG    F+  V     P  +++W+     +    RY ST       SL I   
Sbjct: 5646 LKKIEAFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGMASLTIRKI 5703

Query: 2839 YEEDSGIYTCKATNSKGSATTSGSLRCTGDKN 2870
             +ED G+Y C A N  G  T+   L   G+K+
Sbjct: 5704 RQEDGGLYGCVAVNEYGETTSIVDLH-VGEKH 5734



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 770  PQFIRPLQDLGEL-QEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
            P+F     D  +  ++G NA      T   +P   V WYKDG  +  ++ +         
Sbjct: 5737 PEFAEEELDWSKTARKGENARIT--FTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQ 5794

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             L I  L  +D G+Y   A ++LG++  T +++V
Sbjct: 5795 YLTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKV 5828



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 1724 ENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGT 1782
            E+  A F+  +   G PK  VEW +    I +S +   + D  G  +L +K +  +D+G 
Sbjct: 4    ESGEARFDVTI--EGYPKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61

Query: 1783 YTCRAINELGEAVTSSTLFVQSK 1805
            Y C A N+ G+      L V+ K
Sbjct: 62   YKCVATNDAGQTSLRGDLSVKEK 84



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 4/85 (4%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY--KSTHDFSYVSL 2833
            F+  + ++   E + + FE  ++    P   +EW+     +  G R+    + +    SL
Sbjct: 535  FLRKVEDVTALETEQVWFEIPIQGYPRPI--VEWYRGTTRIKDGGRFTISESEENDMYSL 592

Query: 2834 DITHTYEEDSGIYTCKATNSKGSAT 2858
             I     EDSG Y C A+N  G  T
Sbjct: 593  VIDEARTEDSGPYKCVASNDAGKTT 617



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 26/109 (23%), Positives = 45/109 (41%), Gaps = 8/109 (7%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F+  L+ +   EG    F+      G P  +++W ++   I+ S RF + +     +L
Sbjct: 1021 PTFMSKLEPIEITEGDD--FQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 1078

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745
             +    + D G Y C   +  G   +KA        T+ +    PE LQ
Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFGSVSSKA------DVTVLKKHLRPEVLQ 1121



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 5/126 (3%)

Query: 3405 VRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLK 3464
            V R D  VEE K  AP F      +  ++EG  A     ++    P+  V WY +   + 
Sbjct: 1201 VVRADLEVEE-KNVAPSFHGRQGRLR-VKEGREASVYFEISGKPKPS--VTWYKDDVVIG 1256

Query: 3465 AGSRFRTFCDFGF-VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQ 3523
               R       G      I    PED G Y C A N+ G A  T  + V+ K+ +++  +
Sbjct: 1257 DEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPE 1316

Query: 3524 LPKGME 3529
            + + ++
Sbjct: 1317 IRQQLQ 1322



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 1/56 (1%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGY-VSMTISHVRDEDEGVYMCRASNLLG 2458
            G P   V W++++ +I D  R    +  G     TI   R ED+G Y C A N +G
Sbjct: 1240 GKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVG 1295



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 4/88 (4%)

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSD--FGFVTLDLVDVYERDSGIYTCKAYNKR 2992
            V+ K  P  ++EWY     +  G R+ LT D   G  ++ + D+   D G Y   A+N  
Sbjct: 1725 VKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDI 1784

Query: 2993 GEAFTSSTVYCTSKDNLIERTQHPKGTE 3020
            G+  TS     T K+ LI      + TE
Sbjct: 1785 GK--TSERAELTVKEKLIAPEFEGRETE 1810



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/67 (32%), Positives = 31/67 (46%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            PT  I W+ + +PL    R       +   L I +   ED+G YTC+A N  G+A  S  
Sbjct: 2863 PTPHITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFE 2922

Query: 2863 LRCTGDK 2869
            +  T  K
Sbjct: 2923 VDVTAPK 2929



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 4/85 (4%)

Query: 646  VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF--TSIFRFGYISLDMLSLNI 703
            V A+EG K+ F+TRI   G P   +EW +    +  S ++        G  SL +  +  
Sbjct: 3497 VQAVEGWKVQFQTRI--TGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTK 3554

Query: 704  QDSGEYTCRAVSATGVAETKAVLHV 728
             D G Y C A ++ G +  +  L V
Sbjct: 3555 DDIGTYKCLATNSAGSSACRINLDV 3579



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 943  VEWLKDGRPVEASSRITT--FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000
            VEW +    +    R  T    + G  +L I  V + D+G Y   A N +G+ATT A LT
Sbjct: 4288 VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATTLAELT 4347

Query: 1001 IVTK 1004
            +  K
Sbjct: 4348 VKGK 4351



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 54/193 (27%), Positives = 87/193 (45%), Gaps = 25/193 (12%)

Query: 1900 GF-AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ--SKES-IIRDSQ---HESAL 1952
            GF +AL  L V  ++S E+ C+   +    +    +N Q  S++S II  S    H+ A+
Sbjct: 4456 GFKSALRSLDVTEDESAEFRCEVSGSPAPRIQWF-MNDQPVSRDSRIITSSDGPVHKLAI 4514

Query: 1953 EKIQYLEDDSRYK-RAVQDDSFVVE-----------KPQFGKPIKNAEVTEGHPVHLEAT 2000
             K   L+D   YK  AV D+                KP F + ++  EVT         +
Sbjct: 4515 TKAT-LQDTGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLR--EVTTVFGGEASFS 4571

Query: 2001 LTPVNDPTMRVEWYCN-GRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            +     P  ++ WY +  R + +G RF  + +     L I     +D+GTYMC  +NAVG
Sbjct: 4572 VRVKGFPRPKIVWYKDITRLINRG-RFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVG 4630

Query: 2060 EAVTTSSVKVDAK 2072
            +    S + V+A+
Sbjct: 4631 KETCRSQLVVEAE 4643



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 31/124 (25%), Positives = 52/124 (41%), Gaps = 6/124 (4%)

Query: 2903 VPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL 2962
            VP+ ++  P ++I +     + EG+   LE  VE    P  K+EW+ N K ++     + 
Sbjct: 4745 VPEEDWSAPSFVIELTPT-TVTEGESTALE--VEITGTPLPKVEWFKNDKPVKHDHLVRS 4801

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTS---STVYCTSKDNLIERTQHPKGT 3019
              D   + L +      D+G+Y C   N  G A +    S     +K  + E+       
Sbjct: 4802 YFDGKVIRLIVRRTTLEDAGLYRCTILNDLGTASSMADLSVNRALTKPEVAEKMTDIDAV 4861

Query: 3020 EGLE 3023
            EG E
Sbjct: 4862 EGTE 4865



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 18/73 (24%), Positives = 35/73 (47%)

Query: 2934 QVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            ++  K+ P   +EWY     L  G +++++   G  +L +  V + D+G Y   A N+ G
Sbjct: 5072 EIHVKSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSLTITGVQKDDTGSYKVVATNQAG 5131

Query: 2994 EAFTSSTVYCTSK 3006
             + + + V    K
Sbjct: 5132 SSTSRAEVVVKDK 5144



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 4/118 (3%)

Query: 3255 DSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDL 3314
            ++ +K+    +    Q Q P   + + P F+ Q+       EG    F  ++    +P+ 
Sbjct: 5223 EATSKLGNTSAKFDVQIQAPEA-APKAPAFLKQLLPQNAR-EGDVVKFSCKVTGYPEPE- 5279

Query: 3315 KVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +EW  +G  +    R  T++D     L I      +SG Y+C   N  G  S+ A L
Sbjct: 5280 -IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMYKCTLKNNSGWASSSAEL 5336



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 59/237 (24%), Positives = 90/237 (37%), Gaps = 46/237 (19%)

Query: 3690 EKPNPPRFTV-EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748
            EK   P F   E  + +   EG  V     V+  G P   + W+  G+   T S+  T++
Sbjct: 5436 EKTVAPEFPDRETLEQVVGVEGREVELSTVVK--GLPRPSVKWYKEGKLLHT-SKALTVS 5492

Query: 3749 DFGFIALDIDYIYARDA-----GEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGM 3803
              G    D  Y++   A     G Y C ATN  G+A           RD VL  Q     
Sbjct: 5493 TSG----DTHYVWIPSAKHEHSGRYRCEATNSNGTA----------HRDFVLNIQ----- 5533

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRI 3863
                         +  P E+ +    P F   ++   + E +  RF   +     P   +
Sbjct: 5534 -------------AQVPAEQWVA---PAFTAPLQHIDILEGDTTRFIGEITGVPVPV--V 5575

Query: 3864 EWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
            EWYR+ + +   HR RT  D   V L +      D+G + C   ND G   + A+++
Sbjct: 5576 EWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKCVLRNDLGTVASSASLN 5632



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 3/71 (4%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDF-GYVALDILYTYAEDSGT 2181
            E   A F+  +E    P  T++W+    KI +  +++   D  G  +L I     +D+G 
Sbjct: 4    ESGEARFDVTIEGYPKP--TVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61

Query: 2182 YMCKATNKLGE 2192
            Y C ATN  G+
Sbjct: 62   YKCVATNDAGQ 72



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            ++ EG+ ++L+  +  K  P+  + WY +GK L +     L S      L +      DS
Sbjct: 99   EVFEGESVNLDLTITGKPKPE--VVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDS 156

Query: 2982 GIYTCKAYNKRG 2993
            G Y C+A NK G
Sbjct: 157  GKYKCEAKNKIG 168



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 7/122 (5%)

Query: 1437 DESVTIKPRF--VTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494
            D +V +K +   VT     + V EG+   F C +         + W+K+GQP+    R +
Sbjct: 175  DVNVKVKGKAPTVTSELKPDKVQEGEQYKFTCAV--TGKPKPVISWYKDGQPIKADRRVK 232

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR---STTDIVRSTQNEAG 1551
               D     L I D+  +D G Y     N +G+   +  L      +  ++VR  +N   
Sbjct: 233  DSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEVTPKPAKPEVVRKMENVES 292

Query: 1552 LE 1553
            +E
Sbjct: 293  VE 294



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 10/100 (10%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +V +E D I+F+  V     PT  I W+ + + +    R++        +        ED
Sbjct: 2343 VVVQESDAINFKVRVRGKPVPT--IVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAED 2400

Query: 2843 SGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKA 2882
            +G YTC+A+N  G        +C+ D N++ D    Q +A
Sbjct: 2401 AGTYTCEASNKLG--------KCSRDFNLHVDVPKEQWEA 2432



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 2/50 (4%)

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDLIAEDSGIYTCRAVNLVG 1526
            + W+K+G+P+    R   I   G V  L I++L  ED+G YTC A N +G
Sbjct: 2867 ITWYKDGEPLDDTRRI-DIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIG 2915



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDS 3490
            N+ EG+  + +  +     P L+V WY +G+ L+   R           L I    PEDS
Sbjct: 3598 NVPEGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDS 3655

Query: 3491 GEYLCRAYNNYGEAVTTASMK 3511
            G Y C   +  G +  T  +K
Sbjct: 3656 GLYKCEGVSTLGTSSKTFDVK 3676



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 3/97 (3%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P+      +++ V+GT+     R++  G    +V WF     I +  R+  +   D  +L
Sbjct: 3783 PRIIEKPRDVDAVDGTDAKFTVRVE--GFPQPKVTWFHESTKIVSRGRYEISRVGDLYSL 3840

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407
             +  V     G Y C ATN  G+    C L V  K+D
Sbjct: 3841 VIRGVEYLHVGTYKCIATNDAGKVTAHCHLDV-TKQD 3876



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 2/95 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F   ++++       A F  R+   G P+ ++ W ++   +    R     +     L
Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRV--KGFPRPKIVWYKDITRLINRGRFHISEEGDLYNL 4608

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             ++ V  +DSGTY C   N +G+    S L V+++
Sbjct: 4609 TIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAE 4643



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 3/97 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+   ++ D+   VEG     E  ++    P  KVEWF +  +L +  RY          
Sbjct: 4849 PEVAEKMTDIDA-VEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTST 4905

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            L I  C   ++G Y+ + TN+ G      NL    +E
Sbjct: 4906 LVIRNCTTNDTGPYKVIGTNECGIGGAVLNLIIHERE 4942



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 2/95 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P  T    D    E S+  FE  +   +     VEW+     L  G + +     G   L
Sbjct: 5052 PVITRKIRDAQGEEGSNIRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAYSL 5109

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             I GV + D G Y   ATN+ G +T   ++ VK +
Sbjct: 5110 TITGVQKDDTGSYKVVATNQAGSSTSRAEVVVKDK 5144



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 3/87 (3%)

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            TQ+PR    +K     V G+ A FE  V  ++     + WY +   + S +R     + G
Sbjct: 5342 TQRPRLSDNMKELFATVGGE-ARFE--VTMKATPKPKICWYKDEITLRSRDRYTMKEEDG 5398

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGE 1126
               L I  V+  DSG Y  VA N AG+
Sbjct: 5399 IYTLIIKEVQLSDSGTYKFVASNKAGK 5425



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 29/115 (25%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+    +K + A  GG+  FE  ++    P  KI W K+  ++ +  R+T     G  +L
Sbjct: 5345 PRLSDNMKELFATVGGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIYTL 5402

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751
             +  + + DSG Y   A +  G       L V  + T+       ETL+ +  +E
Sbjct: 5403 IIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK-TVAPEFPDRETLEQVVGVE 5456



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 1037 VKITQK-PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTY 1095
            VK+  K P     LK  +K+ EG+   F   V  +      + WY +G+ I +  R++  
Sbjct: 178  VKVKGKAPTVTSELK-PDKVQEGEQYKFTCAVTGKPK--PVISWYKDGQPIKADRRVKDS 234

Query: 1096 HDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             D     L I  V+ +D G Y V   N  G    +A + V
Sbjct: 235  FDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTADLEV 274



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVT--LDINSVVANDAG 2579
            EG  A +E +    G P  + EW+ +  +++  SRF+ T D    T  L I+ +  +D+G
Sbjct: 294  EGSDAFFEVKFK--GYPIPKREWFHDSKKIEPSSRFKITTDDTEQTSSLVISDLRLDDSG 351

Query: 2580 LYMCKAINRAG 2590
             Y C A N AG
Sbjct: 352  AYQCIASNEAG 362



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 36/126 (28%), Positives = 49/126 (38%), Gaps = 6/126 (4%)

Query: 1965 KRAVQDDSFVVEK---PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021
            K  V+ D  V EK   P F        V EG    +   ++    P   V WY +   + 
Sbjct: 1199 KTVVRADLEVEEKNVAPSFHGRQGRLRVKEGREASVYFEIS--GKPKPSVTWYKDDVVIG 1256

Query: 2022 QGHRFKTTYDFGY-VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL 2080
               R    Y  G      I  A  ED GTY C+A N VG A  T  + V+ K  + +   
Sbjct: 1257 DEDRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPE 1316

Query: 2081 DEQRLK 2086
              Q+L+
Sbjct: 1317 IRQQLQ 1322



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 21/74 (28%), Positives = 32/74 (43%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            +E     R  P   + W+KNG  L  G  ++        TL I     +D+G Y C A N
Sbjct: 1526 VEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARN 1585

Query: 2722 LLGEAVSTASIKIE 2735
             +G A     +++E
Sbjct: 1586 DVGSAERLFEVQVE 1599



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 20/94 (21%), Positives = 41/94 (43%), Gaps = 2/94 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P+    +++A +TE     L   +    DP+   EW  + +PV+      +++D    
Sbjct: 1606 EAPKLTSQLRSARITESDDFELACDVKGTPDPSY--EWLKDDKPVKFDRHLSSSFDGKKC 1663

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             L+       D G+Y     NA G   +++++ +
Sbjct: 1664 TLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDI 1697



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 4/113 (3%)

Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021
            S Y  A  D      KP+  + +K+AE  E      +  +     P   VEWY     + 
Sbjct: 1688 STYSSANLDIVKSKSKPEILETMKDAEGIETGKAKFDVKIKAY--PKAEVEWYHRSARIY 1745

Query: 2022 QGHRFKTTYDF--GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             G R+  T D   G  ++ I     ED GTY   A N +G+    + + V  K
Sbjct: 1746 DGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 2/80 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG     E  V     PT  +EW+  +  +  G R++ T +  Y +L I    ++ +  Y
Sbjct: 2012 EGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSIRDVGDQAAASY 2069

Query: 2847 TCKATNSKGSATTSGSLRCT 2866
             C A N+ G  T    L  T
Sbjct: 2070 KCVAFNNAGRTTYRADLVIT 2089



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 4/88 (4%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNF--GFV 1635
            P+ T  L +++  EG+ A F+  +      T  VEW+     +  G R+   +N   G  
Sbjct: 3031 PLITHKLHDMKAYEGKEARFDIEVTGHPSPT--VEWFKGPSGISEGRRYQLMSNEEQGKH 3088

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVT 1663
            +L +     +D G Y C A N  G+A T
Sbjct: 3089 SLIVSDLNADDDGIYKCVAQNLAGKAST 3116



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK--TYYDFGFVALDIIHATSADTG 1248
            EGK    +  +E  G P+  VEWF     ++ G R++  +  + G  +L +    + D G
Sbjct: 3044 EGKEARFD--IEVTGHPSPTVEWFKGPSGISEGRRYQLMSNEEQGKHSLIVSDLNADDDG 3101

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIER 1272
             Y   A N  G A T A++ VI R
Sbjct: 3102 IYKCVAQNLAGKASTRAMLDVIAR 3125



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 3/95 (3%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            SA  P F + ++ +  + E +SA F   +     P  +++WF N + +    R  T  D 
Sbjct: 4451 SALAPGFKSALRSLD-VTEDESAEFRCEVS--GSPAPRIQWFMNDQPVSRDSRIITSSDG 4507

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
             +  L I     +++G Y+C+A N  G  ++ A+L
Sbjct: 4508 PVHKLAITKATLQDTGVYKCLAVNDNGSATSTADL 4542



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 2507 KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFV 2566
            KP F + L   + ++ G+ A +  RV   G P  +  WY +   L    RF  + +    
Sbjct: 4550 KPTFVERLREVTTVFGGE-ASFSVRVK--GFPRPKIVWYKDITRLINRGRFHISEEGDLY 4606

Query: 2567 TLDINSVVANDAGLYMCKAINRAG 2590
             L I +V  +D+G YMC   N  G
Sbjct: 4607 NLTIENVGRDDSGTYMCILSNAVG 4630



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 15/27 (55%), Positives = 19/27 (70%)

Query: 3625 RDAGLYTCKATNRHGEATVSCKLQVKG 3651
            +D GLY C ATN HGEA++   L V+G
Sbjct: 4717 KDGGLYKCVATNEHGEASMLFNLDVEG 4743



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714
            VEG  V LE  V     P  K+EWF++ V LT   R   +      TL I +   +D+G 
Sbjct: 4861 VEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTLVIRNCTTNDTGP 4918

Query: 2715 YTCKATNLLGEAVSTASIKIEDRHW 2739
            Y    TN  G   +  ++ I +R +
Sbjct: 4919 YKVIGTNECGIGGAVLNLIIHEREF 4943



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 4083 SIEKIREMEASWQVTPEQVVEESKARCPPVF-VSLPDAVTVEEGEWARFCCRVTGHPKPR 4141
            S + +   +A    +  +VV + K   P V  ++    +T+  G        + G PKP 
Sbjct: 5121 SYKVVATNQAGSSTSRAEVVVKDKPLAPKVAEMTATGPITITRGNQLNLNVTIRGKPKPS 5180

Query: 4142 VMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYDTG 4178
            V+W  +GN I+     ++   G +YH  I  T+    G
Sbjct: 5181 VVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAG 5218



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 8/101 (7%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984
            EG V+    +V    +P+  IEW  +G  +E   R     D    TL + +    DSG+Y
Sbjct: 5262 EGDVVKFSCKVTGYPEPE--IEWTRDGVSMESDERVTTWYDGEHSTLSIHNANHADSGMY 5319

Query: 2985 TCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKI 3025
             C   N  G A +S+ +    K      TQ P+ ++ ++++
Sbjct: 5320 KCTLKNNSGWASSSAELVVGGK------TQRPRLSDNMKEL 5354



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/112 (21%), Positives = 49/112 (43%), Gaps = 2/112 (1%)

Query: 4092 ASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            + W  +  ++V   K + P +  ++ +      GE ARF   +   PKP++ W  +  T+
Sbjct: 5327 SGWASSSAELVVGGKTQRPRLSDNMKELFATVGGE-ARFEVTMKATPKPKICWYKDEITL 5385

Query: 4152 VNGSRYKL-TYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
             +  RY +   DG+Y   I + +  D+G  + +             L+V+ +
Sbjct: 5386 RSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEK 5437



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 1/42 (2%)

Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            TVE GE ARF   + G+PKP V W    N I +  ++K+  D
Sbjct: 2    TVESGE-ARFDVTIEGYPKPTVEWYQGKNKIGSSGKHKILED 42



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 6/76 (7%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRF--RTTHDFGFVTLDINSVV 2574
            P E++EG+  + +  +   G P     WY +G  L+       ++T D  F  L I    
Sbjct: 97   PIEVFEGESVNLDLTIT--GKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF--LSIPKAT 152

Query: 2575 ANDAGLYMCKAINRAG 2590
             ND+G Y C+A N+ G
Sbjct: 153  PNDSGKYKCEAKNKIG 168



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR--VKTINDFGFV 3615
            PE      D+   E   A+F  ++         +EW+     +  G R  +KT  +    
Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAF--PKPEIEWYLGATKITDGGRFKIKTDKENCSY 1174

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            IL I  V   DAG   C ATN  G+  V   L+V+
Sbjct: 1175 ILFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVE 1209



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 8/100 (8%)

Query: 917  DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRI---TTFFNFGYVALTIKS 973
            D +   EGG A+F  +++        +EW      +    R    T   N  Y+ L I  
Sbjct: 1124 DDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSYI-LFIDD 1180

Query: 974  VTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQH 1013
            V + DAG   C A NA G+    A+L +  K   +A S H
Sbjct: 1181 VKLDDAGTVKCSATNAAGKTVVRADLEVEEKN--VAPSFH 1218



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRF--RTTHDFGFVTLDINSVVANDAG 2579
            EG  A++  ++     P +  EWY+   ++  G RF  +T  +     L I+ V  +DAG
Sbjct: 1130 EGGKANFAVKIDAFPKPEI--EWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAG 1187

Query: 2580 LYMCKAINRAG 2590
               C A N AG
Sbjct: 1188 TVKCSATNAAG 1198



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 3/95 (3%)

Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750
            K   P    ++KD   V EG    F+ ++   G P+  I+W++       G R     D 
Sbjct: 1407 KCTKPEVLEKMKDVKGV-EGDEATFNVKLS--GYPSPDIEWYYGTTRIRDGGRYKFSRDD 1463

Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
               +L I  +  +D G Y C A+N+ G  T  A++
Sbjct: 1464 QKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAEL 1498



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD- 1231
            SKSKP  ++ + +   +  GK    + +++    P   VEW+H    +  G R+    D 
Sbjct: 1700 SKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDE 1756

Query: 1232 -FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
              G  ++ I      D G Y + A N +G     A + V E+
Sbjct: 1757 EDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 19/67 (28%), Positives = 32/67 (47%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P+  + WY N   +    R + T D     L L D+  +D+G Y C A N  G+AF ++ 
Sbjct: 1930 PEPSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAE 1989

Query: 3001 VYCTSKD 3007
            +    ++
Sbjct: 1990 MTVNKRE 1996



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 20/59 (33%), Positives = 30/59 (50%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            + W+ +G+PL    R+   +      L I  +   DAG YTC+A NR G A  S ++ V
Sbjct: 2867 ITWYKDGEPLDDTRRIDIRSRGNVYYLGILNLKPEDAGTYTCEAGNRIGAAYRSFEVDV 2925



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 16/65 (24%), Positives = 36/65 (55%)

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            +P   + W+++G+ L    R+       L  ++I  L  +D+G Y C+A + +G A+ + 
Sbjct: 3409 NPRPHVVWYRDGILLYDTTRMDIRSRGDLHYVNIYGLTLEDAGNYVCEARSRIGTAIRSC 3468

Query: 2731 SIKIE 2735
            +++I+
Sbjct: 3469 TLEIK 3473



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 5/76 (6%)

Query: 3591 VEWFHNGKPLLTGSRVKTIN--DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ 3648
            VEW+     L    + K     + G   L +  V + D G Y C ATN  G +     L 
Sbjct: 3519 VEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIGTYKCLATNSAGSSACRINLD 3578

Query: 3649 VKGRQGIILEPQLPSH 3664
            VK +Q     P++P H
Sbjct: 3579 VKDKQ---YAPEIPGH 3591



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/67 (32%), Positives = 28/67 (41%)

Query: 3845 EGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYIC 3904
            EG      V  K  P+L + WY++G+LL    R           L I     EDSG Y C
Sbjct: 3601 EGQEINMDVVIKSKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLYKC 3660

Query: 3905 RAVNDFG 3911
              V+  G
Sbjct: 3661 EGVSTLG 3667



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 20/57 (35%), Positives = 27/57 (47%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEA 1794
            G P   VEW ++G  +  +N L       Y  L++      DSGTY   A N+LG A
Sbjct: 3906 GKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSA 3962



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 1/100 (1%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            +P   V W+ +G  L   SR           L I    P+D+G Y+C A +  G    + 
Sbjct: 4179 NPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSC 4238

Query: 3509 SMKVQGKR-NIILESQLPKGMEGTIDKIAALEGYSGTVDT 3547
            ++ V+  R     E Q  K     +  + A+EG+   +DT
Sbjct: 4239 TLDVKAVRPRRGNEVQACKPQTSKMANVTAVEGWKVQLDT 4278



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 3/101 (2%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G  A +E  ++  P P  ++ WY +   L+S  RY    + G   L I  V   DSG Y 
Sbjct: 5359 GGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYK 5416

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
              A N  G+      L V  K ++  +      LE++  +E
Sbjct: 5417 FVASNKAGKTTFLGYLEVMEK-TVAPEFPDRETLEQVVGVE 5456



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 3/100 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E   +PEF   +K  I +K G  A     LE  G    +V W KD  P+  +  I   
Sbjct: 624  VNEKVVQPEFDKEVKP-IEVKHGEEA--TTSLEIKGKPKPKVTWYKDLVPLLETRSIQLK 680

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                   L I + T  D G Y C A N  G A  S ++ +
Sbjct: 681  SVGDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKV 720



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 7/123 (5%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF---TETNNFGF 1634
            P     + +V   EG +A+F  ++        ++EWY     +  G RF   T+  N  +
Sbjct: 1117 PEVLQKMDDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSY 1174

Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDT 1694
            + L I     +D+GT  C A NA G+ V      V  K         +G L R+ +  + 
Sbjct: 1175 I-LFIDDVKLDDAGTVKCSATNAAGKTVVRADLEVEEKNVAPSFHGRQGRL-RVKEGREA 1232

Query: 1695 SKY 1697
            S Y
Sbjct: 1233 SVY 1235



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 19/74 (25%), Positives = 32/74 (43%)

Query: 1997 LEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
            LE +      P+  V WY + R +  G + +           +    A D G+Y C+A N
Sbjct: 1821 LEVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKN 1880

Query: 2057 AVGEAVTTSSVKVD 2070
             VG A    +V+++
Sbjct: 1881 RVGSATRNFNVEIE 1894



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%)

Query: 773  IRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNI 832
            I+ +    E+ EG  A  E +++ V  PT  VEWY     +    R        Y +L+I
Sbjct: 2001 IKEVSKTFEVSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHTLSI 2058

Query: 833  MHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
              +  + A SY   A N  G     A + +  R
Sbjct: 2059 RDVGDQAAASYKCVAFNNAGRTTYRADLVITER 2091



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 15/203 (7%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP F   ++ + + E         +   G P   ++W+++  P+   +R+    D    
Sbjct: 2431 EAPSFKSQLQPVILEEGGTGVLVGEV--AGKPLPTIQWMKDDYPVLFGHRVRPQFDGRTC 2488

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             +  +     D G Y C   N+ GEA +S  L   ++ ++  E   + A   I +  DS 
Sbjct: 2489 KVIFREALIGDGGMYECIIKNQCGEA-SSKALVGVNRGTVGPEIIEKPAGLVIVEGNDS- 2546

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
                R DV +  +  P  +    G  +L++G     + RIE  P+  +        ++ Q
Sbjct: 2547 ----RFDVRIRGHPTPE-VEWFYGSERLTDG----VKYRIESNPEIGLYSLVVSKVQLDQ 2597

Query: 1889 SGH-RYRTSNDFGFA-ALDILTV 1909
            +GH R   SN+ G A AL  LTV
Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTV 2620



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 650  EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEY 709
            EG +I+ +  I+    P +++ W K+G+ ++ + R     R  +  L + S   +DSG Y
Sbjct: 3601 EGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLY 3658

Query: 710  TCRAVSATGVA 720
             C  VS  G +
Sbjct: 3659 KCEGVSTLGTS 3669



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 4/102 (3%)

Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737
            T H   ++T +D  P       E+ + I V EG  V     V   G P   ++WF +G+ 
Sbjct: 3865 TAHCHLDVTKQDFAPIVAGS--EMPEPIVVREGCEVSMMANVR--GKPAPTVEWFKDGQL 3920

Query: 3738 FATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779
             +  + +H      +  LD+      D+G Y   ATN  GSA
Sbjct: 3921 LSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSA 3962



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 2/55 (3%)

Query: 2945 IEWYFNGKVLEQGSRFKLT--SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +EW+   + +  G R+K     D G  +L + DV   DSG Y   A N  GEA T
Sbjct: 4288 VEWFRGEEKITDGGRYKTARMEDEGLYSLIISDVQLEDSGSYRAVASNNLGEATT 4342



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 3/100 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V     KP F   +++  ++  GG A F  R++  G    ++ W KD   +    R    
Sbjct: 4544 VSHCRMKPTFVERLREVTTVF-GGEASFSVRVK--GFPRPKIVWYKDITRLINRGRFHIS 4600

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                   LTI++V   D+G Y C   NA+G+ T  + L +
Sbjct: 4601 EEGDLYNLTIENVGRDDSGTYMCILSNAVGKETCRSQLVV 4640



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            +PV T+ +++    +EG    F+  +     P   VEW+R    +    +   +   G  
Sbjct: 5051 KPVITRKIRDAQG-EEGSNIRFEIHV--KSHPPPHVEWYRGSIKLAHGPKYQISEGDGAY 5107

Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458
            S+TI+ V+ +D G Y   A+N  G
Sbjct: 5108 SLTITGVQKDDTGSYKVVATNQAG 5131



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS-LLIKQIG 137
            K AR  +G NA+    + GNP P V W +    L +     MR     GD+  L I  + 
Sbjct: 5748 KTAR--KGENARITFTVSGNPRPDVVWYKDGMLLFDTTHVDMR---SRGDIQYLTIFGLT 5802

Query: 138  PGDEGEYTCTARNQYGEAICSVYIQPE 164
              D G Y C A+++ G++  +  ++ E
Sbjct: 5803 HDDTGTYVCEAQSRLGKSFRTYALKVE 5829



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 22/102 (21%), Positives = 38/102 (37%), Gaps = 2/102 (1%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            V E +   P +   + D   ++ GE  +  C VTG P P V W  +G  +    R   ++
Sbjct: 722  VAEPQGETPTITTEMTDIQAID-GEDCKLICHVTGEPNPEVEWFKDGKPLKANHRLVPSF 780

Query: 4162 -DGMYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPR 4202
             + M        +  D G+ + +             +KV  R
Sbjct: 781  EERMIALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVEDR 822



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 10/109 (9%)

Query: 1033 TEEEVKITQK---PRFLGPLKGTNKIVEGQSAHFEA--RVEPQSDLTMTVEWYFNGKQIT 1087
            T  E+K+ +K   P F    K T   ++GQ  +     R +P+ ++     W  +G+++ 
Sbjct: 909  TRAELKVNEKHFAPEF-EDWKDTIDALDGQDVNISTWVRGKPKPEIV----WLKDGEELR 963

Query: 1088 SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            +   +Q         L +  V  ED+G+YT  A+N AG      ++TVE
Sbjct: 964  NTMHVQIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDVTITVE 1012



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 4/90 (4%)

Query: 3703 DNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGFIALDIDYI 3760
            D++   EGG  +F  +++    P   I+W+        G R  + T  +     L ID +
Sbjct: 1124 DDVRTVEGGKANFAVKIDAFPKP--EIEWYLGATKITDGGRFKIKTDKENCSYILFIDDV 1181

Query: 3761 YARDAGEYTCRATNKWGSATTTAKITCSAK 3790
               DAG   C ATN  G     A +    K
Sbjct: 1182 KLDDAGTVKCSATNAAGKTVVRADLEVEEK 1211



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/102 (24%), Positives = 42/102 (41%), Gaps = 2/102 (1%)

Query: 3845 EGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF-VSLDILYVYAEDSGEYI 3903
            EG       E    PK  + WY++  ++    R   +Y  G      I     ED G Y 
Sbjct: 1228 EGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPEDKGTYK 1287

Query: 3904 CRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945
            C A ND G  F    I  +   ++++  ++ R   ++E +T+
Sbjct: 1288 CEARNDVGTAFETFPIDVEVKQEVMIAPEI-RQQLQAEDVTE 1328



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 27/115 (23%), Positives = 47/115 (40%), Gaps = 8/115 (6%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+    L+S    E     FE   +  G P    EWLK+ + ++     +S F     +L
Sbjct: 1608 PKLTSQLRSARITESDD--FELACDVKGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTL 1665

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLE 751
            +   + + D G YT    +A G   + A L +       ++   PE L+ ++  E
Sbjct: 1666 NFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIV------KSKSKPEILETMKDAE 1714



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 3/95 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP F + L+    L EG    L  +V  +  P   I+W K+   +  G R++  FD   
Sbjct: 2431 EAPSFKSQLQPVI-LEEGGTGVLVGEVAGKPLPT--IQWMKDDYPVLFGHRVRPQFDGRT 2487

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
              +        D G+Y C   N  GEA S A + +
Sbjct: 2488 CKVIFREALIGDGGMYECIIKNQCGEASSKALVGV 2522



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 16/49 (32%), Positives = 23/49 (46%)

Query: 1478 VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            ++W K+  PV  GHR RP  D     +   + +  D G+Y C   N  G
Sbjct: 2464 IQWMKDDYPVLFGHRVRPQFDGRTCKVIFREALIGDGGMYECIIKNQCG 2512



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 17/66 (25%), Positives = 35/66 (53%)

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            +P   + W+K+G+ L   +R        +   +I  +  +D+G Y C+A N LG +  + 
Sbjct: 2655 NPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSC 2714

Query: 2731 SIKIED 2736
            +I+I++
Sbjct: 2715 TIEIKE 2720



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 2/77 (2%)

Query: 3579 CRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI-NDFGFVI-LEIGGVYQRDAGLYTCKATN 3636
            C ++      + +EWF     L  G + K + +D G  + L +  V   DAG Y C    
Sbjct: 2754 CDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRCVVHT 2813

Query: 3637 RHGEATVSCKLQVKGRQ 3653
              G+ T+  +L +K +Q
Sbjct: 2814 PAGQTTIRGELHIKEKQ 2830



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 16/56 (28%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 2398 CRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFGYVSMTISHVRDEDEGVYMC 2451
            C ++      + +EWFR   ++ D  +  I K+ D   +S+ + +V  ED G Y C
Sbjct: 2754 CDVLVKKSDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTYRC 2809



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 4/78 (5%)

Query: 1586 NVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFVALDIMSCL 1643
            +V+  EG +  F+ R+         VEWY     L    ++   +T   G  +L +    
Sbjct: 3496 DVQAVEGWKVQFQTRITGYPYP--HVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVT 3553

Query: 1644 PEDSGTYTCRAINALGEA 1661
             +D GTY C A N+ G +
Sbjct: 3554 KDDIGTYKCLATNSAGSS 3571



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/101 (20%), Positives = 44/101 (43%), Gaps = 2/101 (1%)

Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            R  + ++D++  P     E +  ++VPEG  ++ D  ++    P + + W+ +G      
Sbjct: 3574 RINLDVKDKQYAPEIPGHEDRQELNVPEGQEINMDVVIK--SKPRLEVSWYKDGELLQDT 3631

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
             R+   +      L I      D+G Y C   +  G+++ T
Sbjct: 3632 KRIDIRSRGDHYYLVIPSAAPEDSGLYKCEGVSTLGTSSKT 3672



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
            EG  ++++  ++      + V W+ +G+ ++   R       D+  L + S  PEDSG+Y
Sbjct: 3601 EGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAAPEDSGLY 3658

Query: 1384 TCQATNQLG 1392
             C+  + LG
Sbjct: 3659 KCEGVSTLG 3667



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            PKF++ +  +  + EG SA    ++    +P   VEWF + + + +  R R+        
Sbjct: 3687 PKFLSHLNSLD-VDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCT 3743

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKA 3370
            L       ++ G Y C ATN+ G  S+ A
Sbjct: 3744 LIFETVNIQDRGAYRCTATNQEGSTSSSA 3772



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 17/59 (28%), Positives = 29/59 (49%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAF 2996
            +  P   +EW+ +G++L   +   L +   +  LDL+   + DSG Y   A N  G A+
Sbjct: 3905 RGKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAY 3963



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 18/65 (27%), Positives = 30/65 (46%)

Query: 2272 PNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAIS 2331
            P   +E++ +G+ L +    H+     Y +LD+      D+G Y   A N LG      +
Sbjct: 3908 PAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTYKFVATNDLGSAYRIFN 3967

Query: 2332 MTVTA 2336
            + VTA
Sbjct: 3968 LNVTA 3972



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 663  VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET 722
            +G+P   + W K+G  +  +SR     R     L++  L   D+G Y C A S  G    
Sbjct: 4177 LGNPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFR 4236

Query: 723  KAVLH---VTPRATIERTSQHPET 743
               L    V PR   E  +  P+T
Sbjct: 4237 SCTLDVKAVRPRRGNEVQACKPQT 4260



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 1175 SKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF 1234
            +KP   + +++   V EG  + LE  +   G P  +VEWF +   +T   R+        
Sbjct: 4847 TKPEVAEKMTDIDAV-EGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDT 4903

Query: 1235 VALDIIHATSADTGEYTVRAVNHLG 1259
              L I + T+ DTG Y V   N  G
Sbjct: 4904 STLVIRNCTTNDTGPYKVIGTNECG 4928



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 17/61 (27%), Positives = 31/61 (50%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            + +P  ++ WY +G +L   +R    S      L++  +   D+G Y C+A +K G+ F 
Sbjct: 4971 RGNPRPEVIWYKDGTLLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFR 5030

Query: 2998 S 2998
            S
Sbjct: 5031 S 5031



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 7/79 (8%)

Query: 2119 ENLKE-----GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILY 2173
            +N+KE     G  A FE  ++    P +   W+ +   +R+  RY    + G   L I  
Sbjct: 5349 DNMKELFATVGGEARFEVTMKATPKPKIC--WYKDEITLRSRDRYTMKEEDGIYTLIIKE 5406

Query: 2174 TYAEDSGTYMCKATNKLGE 2192
                DSGTY   A+NK G+
Sbjct: 5407 VQLSDSGTYKFVASNKAGK 5425



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 7/128 (5%)

Query: 1708 TQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT--TMHDF 1765
            T AP F       +V   +    E   +  G P+  V+W + G  +  S  LT  T  D 
Sbjct: 5438 TVAPEFPDRETLEQVVGVEGREVELSTVVKGLPRPSVKWYKEGKLLHTSKALTVSTSGDT 5497

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK--ASLQLESQHESALQKIQQ 1823
             YV +       E SG Y C A N  G A     L +Q++  A   +     + LQ I  
Sbjct: 5498 HYVWIPS--AKHEHSGRYRCEATNSNGTAHRDFVLNIQAQVPAEQWVAPAFTAPLQHIDI 5555

Query: 1824 LE-DSSRY 1830
            LE D++R+
Sbjct: 5556 LEGDTTRF 5563



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 44/187 (23%), Positives = 70/187 (37%), Gaps = 31/187 (16%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXX 2463
            G P   V+W++  KL+  S  +T +       + I   + E  G Y C A+N  G     
Sbjct: 5468 GLPRPSVKWYKEGKLLHTSKALTVSTSGDTHYVWIPSAKHEHSGRYRCEATNSNG----- 5522

Query: 2464 XXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523
                          T H + +  IQ         ++ P  ++  P FT  L    ++ EG
Sbjct: 5523 --------------TAHRDFVLNIQ---------AQVPAEQWVAPAFTAPLQH-IDILEG 5558

Query: 2524 QHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583
                +   +  V  P +  EWY +   +    R RT  D   V L +     +DAG++ C
Sbjct: 5559 DTTRFIGEITGVPVPVV--EWYRDDRPVTRDHRLRTYSDGRVVILLLRQTNISDAGVFKC 5616

Query: 2584 KAINRAG 2590
               N  G
Sbjct: 5617 VLRNDLG 5623



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDF-GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P   +EW++    + +  + K   D  G  +L I  L  DD+G Y C ATN  G+     
Sbjct: 18   PKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRG 77

Query: 2731 SIKIEDR 2737
             + ++++
Sbjct: 78   DLSVKEK 84



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL-VTLSINSLRNDD 2711
            ++ EG+   +  ++  +  P+  + W+K+ V +    R    +  G     +I   R +D
Sbjct: 1225 RVKEGREASVYFEISGKPKPS--VTWYKDDVVIGDEDRNVDIYSRGSSYYFTIKQARPED 1282

Query: 2712 SGIYTCKATNLLGEAVSTASIKIE 2735
             G Y C+A N +G A  T  I +E
Sbjct: 1283 KGTYKCEARNDVGTAFETFPIDVE 1306



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 2/71 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            ++EGQ A  +  +     P+  VEW++ + L+    +I      G   + I     +D G
Sbjct: 2107 VREGQNAITNMTIR--ARPSPDVEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAG 2164

Query: 2448 VYMCRASNLLG 2458
             Y+C+A+N +G
Sbjct: 2165 TYICKATNSIG 2175



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR--TVYDMGFV 3887
            P+ I +     + E    RF+ R+     P+  +EW+   + L  G +YR  +  ++G  
Sbjct: 2529 PEIIEKPAGLVIVEGNDSRFDVRIRGHPTPE--VEWFYGSERLTDGVKYRIESNPEIGLY 2586

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGE 3912
            SL +  V  + +G Y   A N+ G+
Sbjct: 2587 SLVVSKVQLDQTGHYRIVASNEHGK 2611



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPIT--ASSRITSIFNFGYVSLNIMHLRAEDAG 841
            EG ++ F+ ++     PT  VEW+     +T     RI S    G  SL +  ++ +  G
Sbjct: 2542 EGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQTG 2599

Query: 842  SYTVRAVNKLGEAISTASIRVAAR 865
             Y + A N+ G+A +   + V  R
Sbjct: 2600 HYRIVASNEHGKAQALLDLTVNER 2623



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 19/56 (33%), Positives = 27/56 (48%)

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            +G+P   V W+++  L+ D+SR             I  V  ED G Y+C A N LG
Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLG 2708



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 21/65 (32%), Positives = 28/65 (43%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            V WY +   L   SR    +       +I    PED+GTY C A N LG +  S    + 
Sbjct: 2660 VTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEIK 2719

Query: 1671 SKKSI 1675
              KS+
Sbjct: 2720 EPKSV 2724



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 3/96 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F   +++ +    GG   F  RV+  G P  +I W+ +        R H   +     
Sbjct: 4551 PTFVERLRE-VTTVFGGEASFSVRVK--GFPRPKIVWYKDITRLINRGRFHISEEGDLYN 4607

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
            L I+ +   D+G Y C  +N  G  T  +++   A+
Sbjct: 4608 LTIENVGRDDSGTYMCILSNAVGKETCRSQLVVEAE 4643



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F+ +++  T        F  RV  K  P+ +I WY++   L +  R+    +    +L
Sbjct: 4551 PTFVERLREVTTVFGGEASFSVRV--KGFPRPKIVWYKDITRLINRGRFHISEEGDLYNL 4608

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             I  V  +DSG Y+C   N  G++  ++ +
Sbjct: 4609 TIENVGRDDSGTYMCILSNAVGKETCRSQL 4638



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 8/129 (6%)

Query: 2779 HLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHT 2838
            ++  +    G    FE  ++ +  P  KI W+ +   L S  RY    +    +L I   
Sbjct: 5350 NMKELFATVGGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIYTLIIKEV 5407

Query: 2839 YEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI---YFDTQHPQGKAGLEAVEQAEEARL 2895
               DSG Y   A+N  G  T  G L    +K +   + D +  +   G+E   + E + +
Sbjct: 5408 QLSDSGTYKFVASNKAGKTTFLGYLEVM-EKTVAPEFPDRETLEQVVGVEG-REVELSTV 5465

Query: 2896 AKG-RRPSV 2903
             KG  RPSV
Sbjct: 5466 VKGLPRPSV 5474



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 2523 GQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYM 2582
            G  A +E  V     P  +  WY + + L+   R+    + G  TL I  V  +D+G Y 
Sbjct: 5359 GGEARFE--VTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYK 5416

Query: 2583 CKAINRAG 2590
              A N+AG
Sbjct: 5417 FVASNKAG 5424



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 3/56 (5%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFK--LTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            P  +++WY     +   +R+   LTSD G  +L +  + + D G+Y C A N+ GE
Sbjct: 5667 PPPRVDWYRGTTKITDCNRYSSTLTSD-GMASLTIRKIRQEDGGLYGCVAVNEYGE 5721



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 37/149 (24%), Positives = 64/149 (42%), Gaps = 10/149 (6%)

Query: 1797 SSTLFVQSKASLQLES--QHESALQKIQQLEDSSRYQRREDVEVAVNQ-APRFITQ-LNG 1852
            SSTL     ASL +    Q +  L     + +        D+ V      P F  + L+ 
Sbjct: 5687 SSTLTSDGMASLTIRKIRQEDGGLYGCVAVNEYGETTSIVDLHVGEKHYGPEFAEEELDW 5746

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL-QSGH-RYRTSNDFGFAALDILTVY 1910
                 +G++A     +   P P+  V WY +G +L  + H   R+  D  +  L I  + 
Sbjct: 5747 SKTARKGENARITFTVSGNPRPD--VVWYKDGMLLFDTTHVDMRSRGDIQY--LTIFGLT 5802

Query: 1911 GEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
             +D+G Y C+A + LG++  +  L V+ +
Sbjct: 5803 HDDTGTYVCEAQSRLGKSFRTYALKVEEQ 5831



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 3/100 (3%)

Query: 3415 EKGKAPVFTVP-LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            EK   P F    L   +  R+GENA      T + +P   V WY +G  L   +      
Sbjct: 5732 EKHYGPEFAEEELDWSKTARKGENARIT--FTVSGNPRPDVVWYKDGMLLFDTTHVDMRS 5789

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
                  L I     +D+G Y+C A +  G++  T ++KV+
Sbjct: 5790 RGDIQYLTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKVE 5829



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 4/98 (4%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPV-QQGH-RFKTTYDFGYV 2035
            P+F +   +   T     +   T T   +P   V WY +G  +    H   ++  D  Y 
Sbjct: 5737 PEFAEEELDWSKTARKGENARITFTVSGNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQY- 5795

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
             L I     +DTGTY+C+A + +G++  T ++KV+ ++
Sbjct: 5796 -LTIFGLTHDDTGTYVCEAQSRLGKSFRTYALKVEEQA 5832



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 33/157 (21%), Positives = 60/157 (38%), Gaps = 8/157 (5%)

Query: 3243 GKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQI----QDVTKLVEGQ 3298
            GK  + ++ L  D     + + +    Q       S +  +   QI    Q+  ++ EG+
Sbjct: 45   GKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGE 104

Query: 3299 SAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECV 3358
            S + +  +     P+  V W+ +GK L                L I      +SG+Y+C 
Sbjct: 105  SVNLDLTITGKPKPE--VVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCE 162

Query: 3359 ATNKLGRDST--KANLKCTSKENLILDSQLPRGMEGG 3393
            A NK+G  +     N+K   K   +     P  ++ G
Sbjct: 163  AKNKIGTSARDFDVNVKVKGKAPTVTSELKPDKVQEG 199



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 1704 DEVITQ---APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            D VIT+   AP F     + R+A  +  +    +     P   VEW +    + +  ++ 
Sbjct: 2085 DLVITEREYAPEFE-DFDEKRIAVREGQNAITNMTIRARPSPDVEWYKGDTLLMSDRKID 2143

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
                 G   L ++    +D+GTY C+A N +G   TS  + V  +A
Sbjct: 2144 LKTIGGLYYLEIRKATLDDAGTYICKATNSIGS--TSRRIIVDVEA 2187



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 2518 SELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAND 2577
            ++ +E   A  EA V  V  P+   EW++   +L  G R+R        TL I+++   D
Sbjct: 3294 TDSFECSEARLEAHVAGVPRPT--VEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMED 3351

Query: 2578 AGLYMCKAINRAG 2590
             G Y   A N  G
Sbjct: 3352 TGPYKIIATNEHG 3364



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 31/108 (28%), Positives = 50/108 (46%), Gaps = 8/108 (7%)

Query: 1740 PKLRVEWLRNGVPIEASNR--LTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            PK +V W ++G+ +E S R  L ++ +  YV +     + EDSG Y C   +E       
Sbjct: 4384 PK-QVIWYKDGIRLEDSRRVNLRSVGERYYVVVPS--ASFEDSGIYKCETTSEKETTSQL 4440

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPR 1845
              + ++      L    +SAL+ +   ED S   R    EV+ + APR
Sbjct: 4441 FDIHIEDVCKSALAPGFKSALRSLDVTEDESAEFR---CEVSGSPAPR 4485



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 3/95 (3%)

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            KP F+  L+    +  G+ A F  RV+        + WY +  ++ +  R     +    
Sbjct: 4550 KPTFVERLREVTTVFGGE-ASFSVRVKGFP--RPKIVWYKDITRLINRGRFHISEEGDLY 4606

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             L I +V  +DSG Y  +  NA G+    + + VE
Sbjct: 4607 NLTIENVGRDDSGTYMCILSNAVGKETCRSQLVVE 4641



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 3/89 (3%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            +R   KP   + +T    + EG     E  V+  G P  + EW+ + V+L    R+  + 
Sbjct: 4843 NRALTKPEVAEKMTDIDAV-EGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISE 4899

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                 TL I +   ND G Y     N  G
Sbjct: 4900 TEDTSTLVIRNCTTNDTGPYKVIGTNECG 4928



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 18/74 (24%), Positives = 36/74 (48%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            L   V  R  P   + W+K+G  + T   ++      +  L I   +++ +G Y+C+AT+
Sbjct: 5167 LNLNVTIRGKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEATS 5226

Query: 2722 LLGEAVSTASIKIE 2735
             LG   +   ++I+
Sbjct: 5227 KLGNTSAKFDVQIQ 5240



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT-KTHDFGYV 2434
            P   +  Q    + EG++ + D  +   G P  +V W+++ K +  +  I  K+ D  Y 
Sbjct: 88   PQIKEKEQEPIEVFEGESVNLDLTI--TGKPKPEVVWYKDGKPLRKTKSIDLKSTDDSYF 145

Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458
             ++I      D G Y C A N +G
Sbjct: 146  -LSIPKATPNDSGKYKCEAKNKIG 168



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/68 (29%), Positives = 27/68 (39%)

Query: 1205 GDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264
            G P   +EWF     +  G RF    +    +L I      D G Y   A N  G   T 
Sbjct: 851  GKPEPEIEWFCGPNPIVPGGRFHVTEEGNIQSLAISDLKLEDAGNYKCVASNAAGKTTTR 910

Query: 1265 AIVRVIER 1272
            A ++V E+
Sbjct: 911  AELKVNEK 918



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 28/108 (25%), Positives = 43/108 (39%), Gaps = 4/108 (3%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    P F    + ++ +KEG  A      E  G     V W KD   +    R    
Sbjct: 1208 VEEKNVAPSFHGR-QGRLRVKEGREA--SVYFEISGKPKPSVTWYKDDVVIGDEDRNVDI 1264

Query: 962  FNFGY-VALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
            ++ G     TIK     D G Y C A N +G A  +  + +  K++++
Sbjct: 1265 YSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVM 1312



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 5/116 (4%)

Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297
            K + P  + +++    V EG  A F  ++     P+  IE+Y+    ++   R+  + D 
Sbjct: 1407 KCTKPEVLEKMKDVKGV-EGDEATFNVKLSGYPSPD--IEWYYGTTRIRDGGRYKFSRDD 1463

Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQRPEGLE 2351
               SL I+    +D G Y   A N  G  T    + V  +    I  E Q  E LE
Sbjct: 1464 QKYSLTIKDLNLQDIGTYKCIASNEAGKVTQRAELEVKERDYAPIFEEKQFLEPLE 1519



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 6/96 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV---KTINDFGF 3614
            PEF    +++       +  E         S  V W+ + + LL G +    K  N + F
Sbjct: 1802 PEFEGRETEVPFRAKEKSDLEVSYNINGKPSPDVSWYRDDRLLLDGRKHELRKRGNTYRF 1861

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             +  +      DAG Y C+A NR G AT +  ++++
Sbjct: 1862 TVFNVSA---GDAGSYRCEAKNRVGSATRNFNVEIE 1894



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 2/76 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            I  +EG N      +     P   +EW+  +  L S  +           L+I     +D
Sbjct: 2105 IAVREGQNAITNMTIRARPSPD--VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDD 2162

Query: 2843 SGIYTCKATNSKGSAT 2858
            +G Y CKATNS GS +
Sbjct: 2163 AGTYICKATNSIGSTS 2178



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVE--ASSRITTFFNFGYVALTIKSVTVHD 978
            I EG  + F+ R+   G  T  VEW      +      RI +    G  +L +  V +  
Sbjct: 2540 IVEGNDSRFDVRIR--GHPTPEVEWFYGSERLTDGVKYRIESNPEIGLYSLVVSKVQLDQ 2597

Query: 979  AGHYTCRAYNAIGQATTSANLTI 1001
             GHY   A N  G+A    +LT+
Sbjct: 2598 TGHYRIVASNEHGKAQALLDLTV 2620



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 5/90 (5%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            +P F+  L  +  +  G+ A F  RV+    P +   W+ +  ++    R+  + +    
Sbjct: 4550 KPTFVERLREVTTVFGGE-ASFSVRVKGFPRPKIV--WYKDITRLINRGRFHISEEGDLY 4606

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTC 2197
             L I     +DSGTYMC  +N +G+   TC
Sbjct: 4607 NLTIENVGRDDSGTYMCILSNAVGK--ETC 4634



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 30/138 (21%), Positives = 53/138 (38%), Gaps = 3/138 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F+  L  +    G    F   V+    P  KI W+ +   L +  R+  + +    +L I
Sbjct: 4553 FVERLREVTTVFGGEASFSVRVKGFPRP--KIVWYKDITRLINRGRFHISEEGDLYNLTI 4610

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI-YFDTQHPQGKAGLEAVEQAEEAR 2894
             +   +DSG Y C  +N+ G  T    L    ++   +F     QG   +   + +E   
Sbjct: 4611 ENVGRDDSGTYMCILSNAVGKETCRSQLVVEAEEFAPFFPEDEGQGAVPVVTRQDSEVEL 4670

Query: 2895 LAKGRRPSVPDTEYPKPE 2912
             A  R    P+  + K +
Sbjct: 4671 GAVVRGSPKPEVAWYKDD 4688



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 2/82 (2%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P     M DI   E      E  +I  G P  +VEW R+ V +  ++R T         L
Sbjct: 4849 PEVAEKMTDIDAVEGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTSTL 4906

Query: 1771 NMKYVNPEDSGTYTCRAINELG 1792
             ++     D+G Y     NE G
Sbjct: 4907 VIRNCTTNDTGPYKVIGTNECG 4928



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK  V W ++G  I  S  +          L + +   E +GTY+C A ++LG   TS
Sbjct: 5175 GKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEHAGTYSCEATSKLGN--TS 5232

Query: 1798 STLFVQSKA 1806
            +   VQ +A
Sbjct: 5233 AKFDVQIQA 5241



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
            RFE  V  K  PK +I WY++   L S  RY    + G  +L I  V   DSG Y   A 
Sbjct: 5363 RFE--VTMKATPKPKICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYKFVAS 5420

Query: 3908 NDFGE 3912
            N  G+
Sbjct: 5421 NKAGK 5425



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 6/73 (8%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPL--PSGTRYKSTHDFSYVSLDITHTYEEDSG 2844
            EG++++ +  +     P  ++ W+ + KPL        KST D SY  L I      DSG
Sbjct: 102  EGESVNLDLTITGKPKP--EVVWYKDGKPLRKTKSIDLKSTDD-SYF-LSIPKATPNDSG 157

Query: 2845 IYTCKATNSKGSA 2857
             Y C+A N  G++
Sbjct: 158  KYKCEAKNKIGTS 170



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 5/109 (4%)

Query: 3963 DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF 4022
            DL    K   P  V ++++  S VE     FE +    G P  K EWF + K +   +RF
Sbjct: 271  DLEVTPKPAKPEVVRKMENVES-VEGSDAFFEVKFK--GYPIPKREWFHDSKKIEPSSRF 327

Query: 4023 TPIYDFGYVAMNF--GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
                D      +     +  +DSG Y C A+N  G    +A +K   KP
Sbjct: 328  KITTDDTEQTSSLVISDLRLDDSGAYQCIASNEAGECNLRADLKVKNKP 376



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 9/91 (9%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC- 3473
            EK  AP F      I+ L +G++ +    +     P  ++ W  +G+ L+     +  C 
Sbjct: 917  EKHFAPEFEDWKDTIDAL-DGQDVNISTWVRGKPKP--EIVWLKDGEELRNTMHVQIKCY 973

Query: 3474 -DF-GFVILEISPTYPEDSGEYLCRAYNNYG 3502
             D  G V+ ++SP   ED+G Y CRA NN G
Sbjct: 974  GDLHGLVLYKVSP---EDAGMYTCRAKNNAG 1001



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 6/105 (5%)

Query: 3547 TLTPEA--ESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            T+T EA  + G+ P F +    + ++E       C +         V+WF +   +    
Sbjct: 1008 TITVEALQKKGDTPTFMSKLEPIEITEGDDFQLSCNV--TGRPQPEVQWFRDEVLIKPSR 1065

Query: 3605 RVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            R K   D     L +      D G+Y C  TN  G  +VS K  V
Sbjct: 1066 RFKASYDGNVSALTVKEAELDDDGVYKCVVTNNFG--SVSSKADV 1108



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 19/85 (22%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            ++ EG    L   V  +  P+  ++W+ +  +++   RFK + D     L + +    D 
Sbjct: 1031 EITEGDDFQLSCNVTGRPQPE--VQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDDD 1088

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSK 3006
            G+Y C   N  G   + + V    K
Sbjct: 1089 GVYKCVVTNNFGSVSSKADVTVLKK 1113



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 1043 PRFLGPLKGTNKIVEGQSA--HFEARVEPQSDLTMTVEWYFNGKQITSANR-IQTYHDFG 1099
            P F G  +G  ++ EG+ A  +FE   +P+  +T    WY +   I   +R +  Y    
Sbjct: 1215 PSFHGR-QGRLRVKEGREASVYFEISGKPKPSVT----WYKDDVVIGDEDRNVDIYSRGS 1269

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
                 I   R ED G Y   ARN  G A  +  + VE +  +
Sbjct: 1270 SYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEV 1311



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 6/127 (4%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            ++ ++ E    P    +++   DV EG      C+V    +PT  ++W  N    +   R
Sbjct: 1304 DVEVKQEVMIAPEIRQQLQAE-DVTEGDDCRLTCKVSGYPEPT--LEWLKNNELLSDNDR 1360

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK--RDIVLESQLP- 3800
              T  D     L I  +   DA  Y     N  G  +++AK+    K  +  VLE     
Sbjct: 1361 FKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCTKPEVLEKMKDV 1420

Query: 3801 QGMSGEK 3807
            +G+ G++
Sbjct: 1421 KGVEGDE 1427



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 1/51 (1%)

Query: 4134 VTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYH-FDIPKTRQYDTGKIEVI 4183
            V G PKP V W  NG  + +G   ++   G YH   I ++ + D G  + +
Sbjct: 1532 VRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCL 1582



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)

Query: 2890 AEEARLAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYF 2949
            +E A L    +   P+ E  + E  +P  A+    E   L +   +  K  PD  + WY 
Sbjct: 1788 SERAELTVKEKLIAPEFEGRETE--VPFRAK----EKSDLEVSYNINGKPSPD--VSWYR 1839

Query: 2950 NGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            + ++L  G + +L          + +V   D+G Y C+A N+ G A
Sbjct: 1840 DDRLLLDGRKHELRKRGNTYRFTVFNVSAGDAGSYRCEAKNRVGSA 1885



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 61/249 (24%), Positives = 93/249 (37%), Gaps = 39/249 (15%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            V W+ +G  L   SR    +        I  V   D G Y C+A NR G +  SC +++K
Sbjct: 2660 VTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSCTIEIK 2719

Query: 3651 GRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEG 3710
                   EP+  S   + T +  +L    HK               F  E      VP G
Sbjct: 2720 -------EPK--SVDSTDTRAPGQLIPVKHK---------------FDFE-----GVP-G 2749

Query: 3711 GPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL--NDFGFIALDIDYIYARDAGEY 3768
            G    D  V+      + I+WF        G +   L  +D   ++L ++ +   DAG Y
Sbjct: 2750 GKARCDVLVKK--SDIIDIEWFRGTNMLRDGDKYKILKSDDGQTLSLIVENVCGEDAGTY 2807

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVST 3828
             C      G  T   ++    K+   L   L + +S EK   L +G+  +  K   +  +
Sbjct: 2808 RCVVHTPAGQTTIRGELHIKEKQQAPL--FLDEKVSQEKF-SLPQGQ--EMNKSFTVTGS 2862

Query: 3829 PPKFITQIK 3837
            P   IT  K
Sbjct: 2863 PTPHITWYK 2871



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 800  PTMRVEWYKDGRPITASSR--ITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            P   VEW+KDG+ +  S R  + S  N  Y  L I H+  ED GSY   A +  G +  T
Sbjct: 3158 PKAVVEWFKDGKFLYDSRRMGVRSCGNSHY--LVIYHVTPEDEGSYKCVASSTNGRSSRT 3215

Query: 858  ASIRV 862
              + V
Sbjct: 3216 FDLSV 3220



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 18/79 (22%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 916  KDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVT 975
            + ++++ EG   + +  ++      L V W KDG  ++ + RI       +  L I S  
Sbjct: 3594 RQELNVPEGQEINMDVVIK--SKPRLEVSWYKDGELLQDTKRIDIRSRGDHYYLVIPSAA 3651

Query: 976  VHDAGHYTCRAYNAIGQAT 994
              D+G Y C   + +G ++
Sbjct: 3652 PEDSGLYKCEGVSTLGTSS 3670



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V + A V  +  P   +EWFK+G  L+    L          L +      DSG Y
Sbjct: 3894 EGCEVSMMANVRGKPAPT--VEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQADSGTY 3951

Query: 2716 TCKATNLLGEAVSTASIKI 2734
               ATN LG A    ++ +
Sbjct: 3952 KFVATNDLGSAYRIFNLNV 3970



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 3/112 (2%)

Query: 3540 GYSGTV-DTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGK 3598
            G  G V + +  E E G  PEF     + +    S            +    V W+ +G 
Sbjct: 4928 GIGGAVLNLIIHEREFG--PEFIDEEGEYVKVVRSEGVANITFTVRGNPRPEVIWYKDGT 4985

Query: 3599 PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             L   +R+ T +      L I  +   DAG Y C+A ++ G+   SC L V+
Sbjct: 4986 LLSDTTRMDTRSRGDTHYLNIFSLTSEDAGTYMCEARSKLGKCFRSCILDVQ 5037



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 3/86 (3%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            QRP  +  ++ +     G+ A F+  +     P  K+ W+++E  +    R T   + G 
Sbjct: 5343 QRPRLSDNMKELFATVGGE-ARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGI 5399

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             ++ I  V+  D G Y   ASN  G+
Sbjct: 5400 YTLIIKEVQLSDSGTYKFVASNKAGK 5425



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 7/92 (7%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            ++K   P F  + ++   +V +E  + E      G P   V+W+  GK LLH ++   + 
Sbjct: 5435 MEKTVAPEFPDR-ETLEQVVGVEGREVELSTVVKGLPRPSVKWYKEGK-LLHTSKALTVS 5492

Query: 4027 DFGYVAMNFGWVYP---EDSGEYLCRATNLYG 4055
              G    ++ W+     E SG Y C ATN  G
Sbjct: 5493 TSGDT--HYVWIPSAKHEHSGRYRCEATNSNG 5522



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 30/129 (23%), Positives = 48/129 (37%), Gaps = 3/129 (2%)

Query: 1016 GLEKIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLT 1074
            G  K     DA + S R +  VK  Q  P+     +   ++ EG+S + +  +  +    
Sbjct: 60   GAYKCVATNDAGQTSLRGDLSVKEKQIAPQIKEKEQEPIEVFEGESVNLDLTITGKPK-- 117

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
              V WY +GK +     I          L I      DSG Y   A+N  G +     + 
Sbjct: 118  PEVVWYKDGKPLRKTKSIDLKSTDDSYFLSIPKATPNDSGKYKCEAKNKIGTSARDFDVN 177

Query: 1135 VETRSSIDT 1143
            V+ +    T
Sbjct: 178  VKVKGKAPT 186



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 2/74 (2%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAN 2576
            P ++ EG+   +   V   G P     WY +G  +K   R + + D    TL I  V  +
Sbjct: 193  PDKVQEGEQYKFTCAVT--GKPKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQD 250

Query: 2577 DAGLYMCKAINRAG 2590
            D G Y  +  N  G
Sbjct: 251  DKGTYKVEITNDLG 264



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 3/99 (3%)

Query: 3415 EKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCD 3474
            EK   P F   +  IE ++ GE A     L     P  KV WY +   L      +    
Sbjct: 626  EKVVQPEFDKEVKPIE-VKHGEEA--TTSLEIKGKPKPKVTWYKDLVPLLETRSIQLKSV 682

Query: 3475 FGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
                 LEI    P+D G+Y C A N  G A  +  +KV+
Sbjct: 683  GDEHTLEIINATPDDEGKYKCEATNKAGTAFRSFDIKVK 721



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 2/66 (3%)

Query: 89  AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTA 148
           A F  +  G P P + W     P+V   ++ +   E+    SL I  +   D G Y C A
Sbjct: 843 ASFHCEFSGKPEPEIEWFCGPNPIVPGGRFHV--TEEGNIQSLAISDLKLEDAGNYKCVA 900

Query: 149 RNQYGE 154
            N  G+
Sbjct: 901 SNAAGK 906



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 9/135 (6%)

Query: 2924 VEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGI 2983
            ++GQ +++   V  K  P+  I W  +G+ L      ++        L L  V   D+G+
Sbjct: 934  LDGQDVNISTWVRGKPKPE--IVWLKDGEELRNTMHVQIKCYGDLHGLVLYKVSPEDAGM 991

Query: 2984 YTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDD 3043
            YTC+A N  G      T+   + + L ++   P     LE I+  E     +  Q   + 
Sbjct: 992  YTCRAKNNAGIVSKDVTI---TVEALQKKGDTPTFMSKLEPIEITEG----DDFQLSCNV 1044

Query: 3044 TGRPPEFTTVFKDIV 3058
            TGRP      F+D V
Sbjct: 1045 TGRPQPEVQWFRDEV 1059



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/106 (25%), Positives = 45/106 (42%), Gaps = 7/106 (6%)

Query: 1432 KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH 1491
            K D+      ++P  + +   +  V EG   +F  K++       ++EW+     +T G 
Sbjct: 1105 KADVTVLKKHLRPEVLQKMDDVRTV-EGGKANFAVKIDAFPKP--EIEWYLGATKITDGG 1161

Query: 1492 RFRPIHD---FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            RF+   D     Y+ L I D+  +D+G   C A N  G   V   L
Sbjct: 1162 RFKIKTDKENCSYI-LFIDDVKLDDAGTVKCSATNAAGKTVVRADL 1206



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 2/69 (2%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVT--LDLVDVYERDSGIYTCKAYNKRGEAFTS 2998
            P  +IEWY     +  G RFK+ +D    +  L + DV   D+G   C A N  G+    
Sbjct: 1144 PKPEIEWYLGATKITDGGRFKIKTDKENCSYILFIDDVKLDDAGTVKCSATNAAGKTVVR 1203

Query: 2999 STVYCTSKD 3007
            + +    K+
Sbjct: 1204 ADLEVEEKN 1212



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 7/115 (6%)

Query: 1566 RTDMVDEVTTQAPICTTSLKNVEIKEGQRA--HFERRLIPVSDATLKVEWYHNNKPLKSG 1623
            R D+  E    AP        + +KEG+ A  +FE    P    T    WY ++  +   
Sbjct: 1203 RADLEVEEKNVAPSFHGRQGRLRVKEGREASVYFEISGKPKPSVT----WYKDDVVIGDE 1258

Query: 1624 SRFTETNNFGF-VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYL 1677
             R  +  + G      I    PED GTY C A N +G A  +    V  K+ + +
Sbjct: 1259 DRNVDIYSRGSSYYFTIKQARPEDKGTYKCEARNDVGTAFETFPIDVEVKQEVMI 1313



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 5/103 (4%)

Query: 619  ERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQS 678
            +RA   +   +   ++   QF+ PL+ +   +  ++ +  R    G P   + W KNG+ 
Sbjct: 1494 QRAELEVKERDYAPIFEEKQFLEPLE-IQVRQPVEVSYHVR----GRPKPTVTWWKNGKE 1548

Query: 679  IEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAE 721
            +             Y +L +L    +D+G Y C A +  G AE
Sbjct: 1549 LRDGKHVEIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAE 1591



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 3/98 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P+     K+++ + EG    +E +V     P   +EW+     +  G R + T +    T
Sbjct: 1999 PVIKEVSKTFE-VSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDYHT 2055

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHW 2739
            LSI  + +  +  Y C A N  G     A + I +R +
Sbjct: 2056 LSIRDVGDQAAASYKCVAFNNAGRTTYRADLVITEREY 2093



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 2/95 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P F   ++   + EG    L   +     PT  ++W  +  PV  GHR +  +D    
Sbjct: 2431 EAPSFKSQLQPVILEEGGTGVLVGEVAGKPLPT--IQWMKDDYPVLFGHRVRPQFDGRTC 2488

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             +    A   D G Y C   N  GEA + + V V+
Sbjct: 2489 KVIFREALIGDGGMYECIIKNQCGEASSKALVGVN 2523



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 16/154 (10%)

Query: 4000 VGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAM-NFGWVYPEDSGEYLCRATNLYGMDE 4058
            +G+P   V W+ +G  LL+    T +   G +   N  +V PED+G Y+C A N  G   
Sbjct: 2653 MGNPRPFVTWYKDGI-LLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSF 2711

Query: 4059 TKAVIKTTGKPGI-VYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLP 4117
                I+      +   D++ P  +  ++   + E          V   KARC  V V   
Sbjct: 2712 RSCTIEIKEPKSVDSTDTRAPGQLIPVKHKFDFEG---------VPGGKARC-DVLVKKS 2761

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            D + +   EW R    +    K +++   +G T+
Sbjct: 2762 DIIDI---EWFRGTNMLRDGDKYKILKSDDGQTL 2792



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 3/83 (3%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P+F   L  + ++ EG    F   +   G P   ++W++++  I  + RI    D   V 
Sbjct: 3982 PIFVTELSPL-SVTEGDYTKFVAHVS--GVPLPSIQWYKDDNPISSNHRIRTFFDGHVVK 4038

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + I  +  ED+G Y     N  G
Sbjct: 4039 LLIGQITLEDQGQYKVVLKNESG 4061



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            +P   + + +ID + EG     +  +I  G P  KVEWFR+   + ++ R T +      
Sbjct: 4848 KPEVAEKMTDIDAV-EGTEVRLE--VIKFGCPMPKVEWFRDNVQLTNNDRYTISETEDTS 4904

Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458
            ++ I +    D G Y    +N  G
Sbjct: 4905 TLVIRNCTTNDTGPYKVIGTNECG 4928



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/120 (21%), Positives = 51/120 (42%), Gaps = 3/120 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            ++P+    +K    T G     E T+     P  ++ WY +   ++   R+    + G  
Sbjct: 5343 QRPRLSDNMKELFATVGGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIY 5400

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
             L I      D+GTY   A+N  G+      ++V  K+ +  +  D + L+++  +E  E
Sbjct: 5401 TLIIKEVQLSDSGTYKFVASNKAGKTTFLGYLEVMEKT-VAPEFPDRETLEQVVGVEGRE 5459



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 15/56 (26%), Positives = 29/56 (51%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G+P   V W+++  L+ D++ +          +TI  +  +D G Y+C A + LG+
Sbjct: 5764 GNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCEAQSRLGK 5819



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P   I WY +G+ ++   R K + D    TL + DV + D G Y  +  N  G   +++ 
Sbjct: 212  PKPVISWYKDGQPIKADRRVKDSFDGTTSTLLIKDVKQDDKGTYKVEITNDLGSISSTAD 271

Query: 3001 VYCT---SKDNLIERTQHPKGTEG 3021
            +  T   +K  ++ + ++ +  EG
Sbjct: 272  LEVTPKPAKPEVVRKMENVESVEG 295



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/104 (21%), Positives = 42/104 (40%), Gaps = 3/104 (2%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
           +    P   +P I  ++  + +   G + K    + G P P V W +   PL   ++   
Sbjct: 720 VKVAEPQGETPTITTEM-TDIQAIDGEDCKLICHVTGEPNPEVEWFKDGKPLKANHRLVP 778

Query: 121 RYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPE 164
            + E+   ++L  + I   D G Y C   N +G    +  ++ E
Sbjct: 779 SFEERM--IALSFRPIKLEDMGRYKCVISNVFGSVSSAAEVKVE 820



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 17/75 (22%), Positives = 32/75 (42%)

Query: 4092 ASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            A+ + T    ++ ++    P F    D +   +G+       V G PKP ++WL +G  +
Sbjct: 903  AAGKTTTRAELKVNEKHFAPEFEDWKDTIDALDGQDVNISTWVRGKPKPEIVWLKDGEEL 962

Query: 4152 VNGSRYKLTYDGMYH 4166
             N    ++   G  H
Sbjct: 963  RNTMHVQIKCYGDLH 977



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 3/98 (3%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P   + L+ +EI EG    F+           +V+W+ +   +K   RF  + +    AL
Sbjct: 1021 PTFMSKLEPIEITEGD--DFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 1078

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
             +     +D G Y C   N  G +V+S   +   KK +
Sbjct: 1079 TVKEAELDDDGVYKCVVTNNFG-SVSSKADVTVLKKHL 1115



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 15/54 (27%), Positives = 28/54 (51%)

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS 3817
            D G Y C A N  G+A  T  I    K+++++  ++ Q +  E + E +  R++
Sbjct: 1282 DKGTYKCEARNDVGTAFETFPIDVEVKQEVMIAPEIRQQLQAEDVTEGDDCRLT 1335



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/86 (25%), Positives = 34/86 (39%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            K  PD   EW  + K ++       + D    TL+   V   D G YT    N  G  ++
Sbjct: 1632 KGTPDPSYEWLKDDKPVKFDRHLSSSFDGKKCTLNFKRVQLSDQGSYTVTFKNAHGSTYS 1691

Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLE 3023
            S+ +      +  E  +  K  EG+E
Sbjct: 1692 SANLDIVKSKSKPEILETMKDAEGIE 1717



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 1/78 (1%)

Query: 1204 MGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHT 1263
            MG+P   V W+ +G  +   SR            +I      DTG Y   A N LGS+  
Sbjct: 2653 MGNPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFR 2712

Query: 1264 SAIVRVIERSDI-VTDTQ 1280
            S  + + E   +  TDT+
Sbjct: 2713 SCTIEIKEPKSVDSTDTR 2730



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 18/70 (25%), Positives = 33/70 (47%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            +P   V WY +G  L   SR             I    PED+G Y+C A+N  G +  + 
Sbjct: 2655 NPRPFVTWYKDGILLYDTSRTDMRSRGDIQYCNIFFVGPEDTGTYVCEAHNRLGSSFRSC 2714

Query: 3509 SMKVQGKRNI 3518
            +++++  +++
Sbjct: 2715 TIEIKEPKSV 2724



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 2/82 (2%)

Query: 784  EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
            E   A  EA +  V  PT  VEW+     +    R          +L I +L  ED G Y
Sbjct: 3298 ECSEARLEAHVAGVPRPT--VEWFLGSAKLCDGERYRLEQTDNLYTLVISNLHMEDTGPY 3355

Query: 844  TVRAVNKLGEAISTASIRVAAR 865
             + A N+ G   S   + V  R
Sbjct: 3356 KIIATNEHGSTGSVVDLTVKER 3377



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 5/109 (4%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            PR + + R    V +G  A F  +VE    P  ++ ++H    + S  R+ I+      S
Sbjct: 3783 PRIIEKPRDVDAV-DGTDAKFTVRVEGFPQP--KVTWFHESTKIVSRGRYEISRVGDLYS 3839

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK--GSIISESQRPE 2348
            L I+       G Y   A N  G  T+   + VT +    I++ S+ PE
Sbjct: 3840 LVIRGVEYLHVGTYKCIATNDAGKVTAHCHLDVTKQDFAPIVAGSEMPE 3888



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 6/119 (5%)

Query: 1416 SGLEKIQYLEDTSRYKKT-DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDS 1474
            +G+ K   + D      T D+      +KP FV R + +  V  G+   F  +++     
Sbjct: 4522 TGVYKCLAVNDNGSATSTADLNVSHCRMKPTFVERLREVTTVFGGE-ASFSVRVKGFPRP 4580

Query: 1475 NLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR 1533
              K+ W+K+   +    RF    +     L I ++  +DSG Y C   N VG +  +CR
Sbjct: 4581 --KIVWYKDITRLINRGRFHISEEGDLYNLTIENVGRDDSGTYMCILSNAVGKE--TCR 4635



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 7/114 (6%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL 3494
            G  A FE  +  T  P  K+ WY +  +L++  R+    + G   L I      DSG Y 
Sbjct: 5359 GGEARFEVTMKATPKP--KICWYKDEITLRSRDRYTMKEEDGIYTLIIKEVQLSDSGTYK 5416

Query: 3495 CRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTL 3548
              A N  G+      ++V  K    +  + P     T++++  +EG    + T+
Sbjct: 5417 FVASNKAGKTTFLGYLEVMEK---TVAPEFPD--RETLEQVVGVEGREVELSTV 5465



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP-IHDFGY 1501
            KP    + K IE   EG    F+  +        +V+W++    +T  +R+   +   G 
Sbjct: 5639 KPEINEKLKKIE-AFEGGEARFDLLVTGFPPP--RVDWYRGTTKITDCNRYSSTLTSDGM 5695

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVG 1526
             +L I  +  ED G+Y C AVN  G
Sbjct: 5696 ASLTIRKIRQEDGGLYGCVAVNEYG 5720



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 3/71 (4%)

Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGV 2448
            E   A FD  +     PT  VEW++ +  I  S +     D  G  S+ I  +  +D G 
Sbjct: 4    ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61

Query: 2449 YMCRASNLLGE 2459
            Y C A+N  G+
Sbjct: 62   YKCVATNDAGQ 72



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 2/97 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P+    L++    EG       ++    +PT+  EWLKN + +  + RF + F     +L
Sbjct: 1315 PEIRQQLQAEDVTEGDDCRLTCKVSGYPEPTL--EWLKNNELLSDNDRFKTRFDGQTGTL 1372

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRAT 733
             + ++ + D+  Y     +  G   + A L V  + T
Sbjct: 1373 TIRNVTLADAVPYKVVVRNDAGEVSSSAKLKVIRKCT 1409



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 1442 IKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGY 1501
            +KP      K+ E V EG     E K+  V      VEW+     V  G RF+   +  Y
Sbjct: 1997 VKPVIKEVSKTFE-VSEGGTASIEVKVSGVPVPT--VEWYHGSNRVLDGDRFQVTQEGDY 2053

Query: 1502 VALDIIDLIAEDSGIYTCRAVNLVG 1526
              L I D+  + +  Y C A N  G
Sbjct: 2054 HTLSIRDVGDQAAASYKCVAFNNAG 2078



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/91 (26%), Positives = 34/91 (37%), Gaps = 2/91 (2%)

Query: 4117 PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF-DIPKTRQY 4175
            P  V V EGE A+    V G PK  V W  +G  + +  R  +   G  H+  I      
Sbjct: 3137 PKPVIVNEGEEAQMMVSVRGRPKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPE 3196

Query: 4176 DTGKIEVIXXXXXXXXXXXXXLKV-IPRHDD 4205
            D G  + +             L V +P+  D
Sbjct: 3197 DEGSYKCVASSTNGRSSRTFDLSVKVPKPKD 3227



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 4/91 (4%)

Query: 917  DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--ITTFFNFGYVALTIKSV 974
            + +   EG    F+ R+   G     VEW +    +  S +  I      G  +L +  V
Sbjct: 3495 NDVQAVEGWKVQFQTRIT--GYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDV 3552

Query: 975  TVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
            T  D G Y C A N+ G +    NL +  K+
Sbjct: 3553 TKDDIGTYKCLATNSAGSSACRINLDVKDKQ 3583



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 4/91 (4%)

Query: 1318 HNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY--EFDYVALDLLSV 1375
            ++++ VEG  V  + R+   G     VEW+     +    +++ A   E    +L +  V
Sbjct: 3495 NDVQAVEGWKVQFQTRI--TGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDV 3552

Query: 1376 YPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
              +D G Y C ATN  G +     L V  K+
Sbjct: 3553 TKDDIGTYKCLATNSAGSSACRINLDVKDKQ 3583



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 14/143 (9%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY---DGMYHFDIPKTRQYD 4176
            V   EG   +F  R+TG+P P V W      + +  +YK+     DG+Y   +    + D
Sbjct: 3497 VQAVEGWKVQFQTRITGYPYPHVEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDD 3556

Query: 4177 TGKIEVIXXXXXXXXXXXXXLKV--------IPRHDDYRGVLKNAPRPWYDETTQYQRTE 4228
             G  + +             L V        IP H+D + +  N P           +++
Sbjct: 3557 IGTYKCLATNSAGSSACRINLDVKDKQYAPEIPGHEDRQEL--NVPEGQEINMDVVIKSK 3614

Query: 4229 TELEKT-FEERQVLQRQGVIDHR 4250
              LE + +++ ++LQ    ID R
Sbjct: 3615 PRLEVSWYKDGELLQDTKRIDIR 3637



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC--DFGFVILEISPTYPEDSG 3491
            EG    F+ R+T    P+  VEWY     L    +++     + G   L ++    +D G
Sbjct: 3501 EGWKVQFQTRITGYPYPH--VEWYRGTIKLHDSDKYKIAQTKEDGLYSLIVNDVTKDDIG 3558

Query: 3492 EYLCRAYNNYGEAVTTASMKVQGKR 3516
             Y C A N+ G +    ++ V+ K+
Sbjct: 3559 TYKCLATNSAGSSACRINLDVKDKQ 3583



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/93 (21%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P   + L ++++ EG  A    ++    + T  VEW+ +++ + +  R   +       L
Sbjct: 3687 PKFLSHLNSLDVDEGDSAKLTCKMFGKPEPT--VEWFKDDQLITNNDRVRSSVVGNTCTL 3744

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
               +   +D G Y C A N  G   +S + +V+
Sbjct: 3745 IFETVNIQDRGAYRCTATNQEGSTSSSAVIVVN 3777



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 2/84 (2%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P+  +EW+ + +++    R + +      TL    V  +D G Y C A N+ G   +SS 
Sbjct: 3714 PEPTVEWFKDDQLITNNDRVRSSVVGNTCTLIFETVNIQDRGAYRCTATNQEGST-SSSA 3772

Query: 3001 VYCTSKDNLIER-TQHPKGTEGLE 3023
            V   ++ ++  R  + P+  + ++
Sbjct: 3773 VIVVNRASITPRIIEKPRDVDAVD 3796



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 2/80 (2%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            +G +  F   VE    P  K+ WF  +  + S  RY+ +      SL I        G Y
Sbjct: 3796 DGTDAKFTVRVEGFPQP--KVTWFHESTKIVSRGRYEISRVGDLYSLVIRGVEYLHVGTY 3853

Query: 2847 TCKATNSKGSATTSGSLRCT 2866
             C ATN  G  T    L  T
Sbjct: 3854 KCIATNDAGKVTAHCHLDVT 3873



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 1/69 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDI 4169
            P FV      TV EGE       +TG P P+V W  N   + +    +  +DG +    +
Sbjct: 4753 PSFVIELTPTTVTEGESTALEVEITGTPLPKVEWFKNDKPVKHDHLVRSYFDGKVIRLIV 4812

Query: 4170 PKTRQYDTG 4178
             +T   D G
Sbjct: 4813 RRTTLEDAG 4821



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 3/71 (4%)

Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF-GYVSLNIMHLRAEDAGS 842
           E   A F+  +     PT  VEWY+    I +S +   + +  G  SL I  L  +DAG+
Sbjct: 4   ESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGA 61

Query: 843 YTVRAVNKLGE 853
           Y   A N  G+
Sbjct: 62  YKCVATNDAGQ 72



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 2941 PDLKIEWYFN-GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            P   +EWY    K+   G    L  D G  +L + D+ + D+G Y C A N  G+
Sbjct: 18   PKPTVEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQ 72



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 1/64 (1%)

Query: 1611 VEWYHN-NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            VEWY   NK   SG      ++ G  +L I     +D+G Y C A N  G+    G   V
Sbjct: 22   VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAGAYKCVATNDAGQTSLRGDLSV 81

Query: 1670 HSKK 1673
              K+
Sbjct: 82   KEKQ 85



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 2/79 (2%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            +E  +    P F      + V+EG  A     ++G PKP V W  +   I +  R    Y
Sbjct: 1206 LEVEEKNVAPSFHGRQGRLRVKEGREASVYFEISGKPKPSVTWYKDDVVIGDEDRNVDIY 1265

Query: 4162 D--GMYHFDIPKTRQYDTG 4178
                 Y+F I + R  D G
Sbjct: 1266 SRGSSYYFTIKQARPEDKG 1284



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/70 (28%), Positives = 33/70 (47%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P+  +EWL+N   +  ++R  T  D     L ++ V   D+  Y     N+ GE  +S
Sbjct: 1340 GYPEPTLEWLKNNELLSDNDRFKTRFDGQTGTLTIRNVTLADAVPYKVVVRNDAGEVSSS 1399

Query: 1798 STLFVQSKAS 1807
            + L V  K +
Sbjct: 1400 AKLKVIRKCT 1409



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            + + K K P     + + E +  G+ A F+ ++     P  +VEWY     +  G R+  
Sbjct: 1697 IVKSKSK-PEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCL 1752

Query: 3472 FCDF--GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
              D   G   + I+    ED G Y   A+N+ G+    A + V+ K
Sbjct: 1753 TQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 1798



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 3/91 (3%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            E P F +Q+Q V  L EG +      +     P   ++W  +   +  GHR R   D   
Sbjct: 2431 EAPSFKSQLQPVI-LEEGGTGVLVGEVAGKPLPT--IQWMKDDYPVLFGHRVRPQFDGRT 2487

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKA 3370
              +        + G YEC+  N+ G  S+KA
Sbjct: 2488 CKVIFREALIGDGGMYECIIKNQCGEASSKA 2518



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 2/80 (2%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG+   +   V  R  P   +EWFK+G  L    R+          L I  +  +D G Y
Sbjct: 3144 EGEEAQMMVSVRGR--PKAVVEWFKDGKFLYDSRRMGVRSCGNSHYLVIYHVTPEDEGSY 3201

Query: 2716 TCKATNLLGEAVSTASIKIE 2735
             C A++  G +  T  + ++
Sbjct: 3202 KCVASSTNGRSSRTFDLSVK 3221



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 917  DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTV 976
            + I ++EG      A +   G     VEW KDG+ +  ++ +       Y  L +   T 
Sbjct: 3888 EPIVVREGCEVSMMANVR--GKPAPTVEWFKDGQLLSNTNNLHLRARGEYFNLDLLKTTQ 3945

Query: 977  HDAGHYTCRAYNAIGQATTSANLTI 1001
             D+G Y   A N +G A    NL +
Sbjct: 3946 ADSGTYKFVATNDLGSAYRIFNLNV 3970



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 2/93 (2%)

Query: 3978 QIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTP--IYDFGYVAMNF 4035
            Q     ++  +E  K +      G P   VEWF   + +    R+    + D G  ++  
Sbjct: 4259 QTSKMANVTAVEGWKVQLDTRMTGYPVPIVEWFRGEEKITDGGRYKTARMEDEGLYSLII 4318

Query: 4036 GWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
              V  EDSG Y   A+N  G   T A +   GK
Sbjct: 4319 SDVQLEDSGSYRAVASNNLGEATTLAELTVKGK 4351



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 17/69 (24%), Positives = 35/69 (50%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G+P+  V W ++G+ +  +  +          L +  +  +D+GTY C A + LG++  +
Sbjct: 5764 GNPRPDVVWYKDGMLLFDTTHVDMRSRGDIQYLTIFGLTHDDTGTYVCEAQSRLGKSFRT 5823

Query: 1798 STLFVQSKA 1806
              L V+ +A
Sbjct: 5824 YALKVEEQA 5832



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 3/81 (3%)

Query: 649 MEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSG 707
           +E G+  F+  IE    PT  +EW +    I +S +   +    G  SL +  L   D+G
Sbjct: 3   VESGEARFDVTIEGYPKPT--VEWYQGKNKIGSSGKHKILEDDDGKCSLIIKDLTKDDAG 60

Query: 708 EYTCRAVSATGVAETKAVLHV 728
            Y C A +  G    +  L V
Sbjct: 61  AYKCVATNDAGQTSLRGDLSV 81



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 8/94 (8%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV--TIGHRF 1493
            ++E V ++P F    K IE V  G+       LE       KV W+K+  P+  T   + 
Sbjct: 624  VNEKV-VQPEFDKEVKPIE-VKHGEEA--TTSLEIKGKPKPKVTWYKDLVPLLETRSIQL 679

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527
            + + D     L+II+   +D G Y C A N  GT
Sbjct: 680  KSVGDEH--TLEIINATPDDEGKYKCEATNKAGT 711



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 2/66 (3%)

Query: 800  PTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            P   + W KDG  +  +  +  I  +G +  L +  +  EDAG YT RA N  G      
Sbjct: 949  PKPEIVWLKDGEELRNTMHV-QIKCYGDLHGLVLYKVSPEDAGMYTCRAKNNAGIVSKDV 1007

Query: 859  SIRVAA 864
            +I V A
Sbjct: 1008 TITVEA 1013



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 2/69 (2%)

Query: 2925 EGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIY 2984
            EGQ       +  +  PD  +EWY    +L    +  L +  G   L++      D+G Y
Sbjct: 2109 EGQNAITNMTIRARPSPD--VEWYKGDTLLMSDRKIDLKTIGGLYYLEIRKATLDDAGTY 2166

Query: 2985 TCKAYNKRG 2993
             CKA N  G
Sbjct: 2167 ICKATNSIG 2175



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 5/100 (5%)

Query: 3966 DVDKKQ--PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFT 4023
            DV K+Q   P F +Q+Q    L E  T     ++A  G P   ++W  +  P+L  +R  
Sbjct: 2424 DVPKEQWEAPSFKSQLQP-VILEEGGTGVLVGEVA--GKPLPTIQWMKDDYPVLFGHRVR 2480

Query: 4024 PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
            P +D     + F      D G Y C   N  G   +KA++
Sbjct: 2481 PQFDGRTCKVIFREALIGDGGMYECIIKNQCGEASSKALV 2520



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 16/53 (30%), Positives = 24/53 (45%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            P F S    V +EEG        V G P P + W+ +   ++ G R +  +DG
Sbjct: 2433 PSFKSQLQPVILEEGGTGVLVGEVAGKPLPTIQWMKDDYPVLFGHRVRPQFDG 2485



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/66 (27%), Positives = 31/66 (46%)

Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
            +P   V W+ +G  L    R    +      L+I  +  +D+G Y C+A + LG    S 
Sbjct: 4179 NPRPAVFWFKDGVQLYETSRMDMRSRDSLQYLNIFGLTPDDAGTYVCEARSRLGTCFRSC 4238

Query: 1933 RLNVQS 1938
             L+V++
Sbjct: 4239 TLDVKA 4244



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/92 (22%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            +  P FV +++  T++   E + F  ++   G P  K+ W+ +   L+++ RF    +  
Sbjct: 4548 RMKPTFVERLREVTTVFGGEAS-FSVRVK--GFPRPKIVWYKDITRLINRGRFHISEEGD 4604

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
               +    V  +DSG Y+C  +N  G +  ++
Sbjct: 4605 LYNLTIENVGRDDSGTYMCILSNAVGKETCRS 4636



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 2177 EDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPN-GLEKIRQLEAQGHSTRIEVE 2235
            +D G Y C ATN+ GEA     L V GH     D   P+  +E       +G ST +EVE
Sbjct: 4717 KDGGLYKCVATNEHGEASMLFNLDVEGHVP-EEDWSAPSFVIELTPTTVTEGESTALEVE 4775



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            I    G  ++L   ++  G     V W+ +G  I T    +     D   L +L    E 
Sbjct: 5159 ITITRGNQLNLNVTIR--GKPKPSVVWYKDGNKILTSRNVQIRSCGDVYHLIILFTKSEH 5216

Query: 1380 SGVYTCQATNQLG 1392
            +G Y+C+AT++LG
Sbjct: 5217 AGTYSCEATSKLG 5229



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            V W+ +G  +LT   V+ I   G V  L I       AG Y+C+AT++ G  +    +Q+
Sbjct: 5181 VVWYKDGNKILTSRNVQ-IRSCGDVYHLIILFTKSEHAGTYSCEATSKLGNTSAKFDVQI 5239

Query: 3650 KGRQGIILEPQLPSHFK 3666
            +  +     P+ P+  K
Sbjct: 5240 QAPEA---APKAPAFLK 5253


>SB_8819| Best HMM Match : I-set (HMM E-Value=0)
          Length = 1789

 Score =  161 bits (390), Expect = 2e-38
 Identities = 113/413 (27%), Positives = 188/413 (45%), Gaps = 21/413 (5%)

Query: 4404 PVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFS 4463
            P    +PP FT +++P +  E+EQ     E D  P   I++ ++  P K   +   ++F 
Sbjct: 641  PKDKQQPPTFTSEVKPVQANENEQVSVVFEADLTPDSKIEFLKDGKPFKGDENSD-YSFD 699

Query: 4464 TKSILI-IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
             ++IL+  +    +DS  +  V  N+ G +     + +E K+ + +  +     T   + 
Sbjct: 700  GRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEIT---KP 756

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            V V   + V+L  +   T    + WLK+GK   PD R+    +    TL++ +   +D+G
Sbjct: 757  VVVKEKEQVKLVFEADVTPDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTG 816

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             YECV  N  G  +C +   V     K +PK      +  PE + P+K+    E     F
Sbjct: 817  TYECVIANKYG--KCSSPVDV-----KVEPK------HLKPEAVTPMKNIDAVESGQARF 863

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE--YTLRISEAFPEDEGDYKCVAYNS 4700
              ++ G P P  +WY G   +  S   ++ +  D+  YTL I      D G YK +  N 
Sbjct: 864  EVEVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNL 923

Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
            AG  T  A+LKV + + A      T  + I V +GQ      +I SK KP + WL++G  
Sbjct: 924  AGTTTNKAELKVKEKEVAPEF-IQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKT 982

Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +  +        G+   L+I  +  EDTGT+TC AT   G+  +   + VK +
Sbjct: 983  LSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGE 1035



 Score =  161 bits (390), Expect = 2e-38
 Identities = 117/394 (29%), Positives = 177/394 (44%), Gaps = 28/394 (7%)

Query: 4411 PIFTK-KMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-STKSIL 4468
            P F K +++P  V + E+A   +   G+P P + W+++  P++ S + Q  +   T SI 
Sbjct: 1231 PEFDKDEVEPIEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIR 1290

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
            I+R    ED+  +   A N  G  K S N  +  K          P+F    Q + VT  
Sbjct: 1291 IVR-TSPEDAGTYMCEATNPSG--KASKNFDIGIKGE-------APTFASKLQPIQVTEE 1340

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVA 4588
               +L  KV+G     + W K+G+ V+ D+R K   +  T TL        D G+YE   
Sbjct: 1341 DECKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEV 1400

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
             N+ G  R  A+  V   + K             PEI+  + D    E +  +F   I G
Sbjct: 1401 TNNFGTVRTSADVDVQKRSVK-------------PEIMGKVDDIEAVETEQAQFDIPIKG 1447

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTA--DEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             P P V+WY G   I     F++S +   D Y+L IS    +D G YKCVA N AG+ T 
Sbjct: 1448 YPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKATA 1507

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPD 4766
               L V +            +  I V +G+ A    +I  K KP + W ++G ++ ET +
Sbjct: 1508 RVNLDVKEKMFQPEFDR-DEVEPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRN 1566

Query: 4767 FQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             Q++  GN   + I  T  +D GT+ C AT  AG
Sbjct: 1567 IQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAG 1600



 Score =  150 bits (364), Expect = 2e-35
 Identities = 172/732 (23%), Positives = 297/732 (40%), Gaps = 58/732 (7%)

Query: 4095 QVTPEQVVEESKARCPPVFV-SLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN 4153
            ++T E   E+ +A   PVF+  +   V V+E E  +        P  ++ WL +G     
Sbjct: 734  KITIEPKKEKKQA---PVFIHEITKPVVVKEKEQVKLVFEADVTPDSKIEWLKDGKPFTP 790

Query: 4154 GSRYKLTYDG-MYHFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVIPRHDDYRGVLKN 4212
              R   T+DG +    +  T   DTG  E +             +KV P+H     V   
Sbjct: 791  DQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPKHLKPEAV--- 847

Query: 4213 APRPWYDETTQYQ-RTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKR 4271
             P    D     Q R E E+  +  E +     G        K K+IK  E +   ++  
Sbjct: 848  TPMKNIDAVESGQARFEVEVSGS-PEPKFEWYHGSTKLNDSDKHKIIK-AEDKPLYTLII 905

Query: 4272 KKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLD--QT 4329
            +  +     L +L     I  +    +T++  +   KV    VA    Q     +D  Q 
Sbjct: 906  ENVDTTDGGLYKL-----ITSNLAGTTTNKAEL---KVKEKEVAPEFIQTDTKPIDVEQG 957

Query: 4330 EEVTEQRVQKKVTQKPRIP--DPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTET 4387
            ++VT    + K   KP++      ++    K +    +  T + V+  K+ T + T T T
Sbjct: 958  QDVTAS-FKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVI--KKSTPEDTGTYT 1014

Query: 4388 TEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRE 4447
                +            VK   P + + K+QP +V E +  +   +  G P P IKW+++
Sbjct: 1015 CTATNNIGKCSSDFTVNVKGEAPTL-SSKLQPVQVTEEDDCKLTCKVSGLPEPTIKWFKD 1073

Query: 4448 NFPIKNSPDFQIH-TFSTKS-ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRR 4505
              P+K+  D +I  T+  K+  L  + + ++D   +     N  GT + SA++ V+ +  
Sbjct: 1074 GEPVKS--DLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRN- 1130

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKI-- 4562
                  V P       ++     +  R D  + G  KP+ V W     ++    R K+  
Sbjct: 1131 ------VKPEIVGKVHDIEALETEQARFDIPIKGYPKPV-VEWFHGPTRILDGGRFKLSE 1183

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
             EE+  Y+L+I +    D G Y+CVA N AG+    A   V         K +       
Sbjct: 1184 SEENDMYSLVISDLVMDDLGTYKCVANNDAGKTTARANLDV---------KEKMFQPEFD 1234

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
             + +EP++   V +G+    S  I GKP P V W+K  K ++ SK  Q     D Y++RI
Sbjct: 1235 KDEVEPIE---VKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRI 1291

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                PED G Y C A N +G+ +    + +    + +     + L+ I V E    +   
Sbjct: 1292 VRTSPEDAGTYMCEATNPSGKASKNFDIGI----KGEAPTFASKLQPIQVTEEDECKLTC 1347

Query: 4743 QITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            +++   +PTI+W ++G  +      +  ++G    L       +D G +    T   G V
Sbjct: 1348 KVSGLPEPTIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTV 1407

Query: 4803 ETSAKLVVKSKT 4814
             TSA + V+ ++
Sbjct: 1408 RTSADVDVQKRS 1419



 Score =  144 bits (348), Expect = 2e-33
 Identities = 106/409 (25%), Positives = 187/409 (45%), Gaps = 32/409 (7%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-TFSTKSI-L 4468
            P F  K+QP +V E ++ +   +  G P P IKW+++  P+K+  D +I  T+  K+  L
Sbjct: 1326 PTFASKLQPIQVTEEDECKLTCKVSGLPEPTIKWFKDGEPVKS--DLRIKPTYDGKTCTL 1383

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
              + + ++D   +     N  GT + SA++ V+++        V P       ++     
Sbjct: 1384 TFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRS-------VKPEIMGKVDDIEAVET 1436

Query: 4529 QLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYPQDSGKYE 4585
            +  + D  + G  KP+ V W     ++    R KI E  E+  Y+L+I      D G Y+
Sbjct: 1437 EQAQFDIPIKGYPKPV-VEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYK 1495

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA N AG+A       V+L   +   +P+        + +EP++   V +G+    S +
Sbjct: 1496 CVASNDAGKATAR----VNLDVKEKMFQPEFDR-----DEVEPIE---VKQGEEASTSLE 1543

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            I GKP P V WYK  K+++ ++  Q+    + Y++ I    P+D G Y C A N AG  T
Sbjct: 1544 IQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAG--T 1601

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQIT-SKIKPTIQWLREGALIPET 4764
             + K  +    +   L   + L+ + V EG   +    +T    KP I+W ++G  +   
Sbjct: 1602 SSRKFDIKVSGEGPKL--ASELQPMQVTEGDDCKLSCNVTEGTTKPIIKWFKDGEPVKSD 1659

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
               +  + G   +L +      D G +    T   G V++SA + V+ +
Sbjct: 1660 HRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRR 1708



 Score =  136 bits (328), Expect = 5e-31
 Identities = 118/448 (26%), Positives = 199/448 (44%), Gaps = 36/448 (8%)

Query: 4376 KEITRKITSTETTEIEHKAQTQERVVEGPVKPSKP----PIFTKKM-QPCRVFEHEQARF 4430
            K  T+K + T    + +K       V+  ++P K     P+F  ++ +P  V E EQ + 
Sbjct: 708  KNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITKPVVVKEKEQVKL 767

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSI-LIIRQVFVEDSAVFAAVAENR 4488
              E D  P   I+W ++  P   +PD +  +TF  + I L+++   V+D+  +  V  N+
Sbjct: 768  VFEADVTPDSKIEWLKDGKPF--TPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANK 825

Query: 4489 GGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWL 4548
             G  KCS+ + V+ + +  +   V P   + A    V SGQ  R + +V+G+      W 
Sbjct: 826  YG--KCSSPVDVKVEPKHLKPEAVTPMKNIDA----VESGQ-ARFEVEVSGSPEPKFEWY 878

Query: 4549 KNGKKVQPDIRNKIL--EEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
                K+    ++KI+  E+   YTL+I      D G Y+ +  N AG             
Sbjct: 879  HGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAG------------- 925

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
             T +K + + K     PE I+     I V +GQ +  S KI  KP P V W K  K +  
Sbjct: 926  TTTNKAELKVKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSS 985

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            SK    +   D Y L I ++ PED G Y C A N+ G+   ++   V    +A  L   +
Sbjct: 986  SKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGK--CSSDFTVNVKGEAPTLS--S 1041

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
             L+ + V E    +   +++   +PTI+W ++G  +      +  ++G    L       
Sbjct: 1042 KLQPVQVTEEDDCKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITM 1101

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +D G +  + T   G V TSA + V+ +
Sbjct: 1102 DDGGEYEVQVTNNFGTVRTSADIAVQRR 1129



 Score =  120 bits (288), Expect = 4e-26
 Identities = 97/396 (24%), Positives = 161/396 (40%), Gaps = 30/396 (7%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K S  P    K+      E EQA+F++   G P P+++WY     I +   F+I      
Sbjct: 1417 KRSVKPEIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEWYHGPTRILDGGRFKISESEEN 1476

Query: 4466 SI--LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL-TAQN 4522
             +  L+I  + ++D   +  VA N  G A    NL V+EK  Q       P F     + 
Sbjct: 1477 DMYSLVISNLIMDDLGTYKCVASNDAGKATARVNLDVKEKMFQ-------PEFDRDEVEP 1529

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            + V  G+      ++ G     V W K+GK ++     +++    TY++ I+   P D G
Sbjct: 1530 IEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVG 1589

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y C A N AG +                 K   K +   P++   L+   V EG   + 
Sbjct: 1590 TYMCEATNKAGTS---------------SRKFDIKVSGEGPKLASELQPMQVTEGDDCKL 1634

Query: 4643 SCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            SC +  G   P ++W+K  + +K     + S       L +      D GDY+    N  
Sbjct: 1635 SCNVTEGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKF 1694

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            G V  +A + V + +    +  +  + DI   E + A+F   I    KP ++W      I
Sbjct: 1695 GTVKSSADIDVQRRNVKPEI--VGNVDDIEAVETEQARFDITIKGYPKPVVEWYHGPTRI 1752

Query: 4762 PETPDFQMIHEGNNAV--LLIGNTYEEDTGTFTCRA 4795
             +   F++     N +  L+I +   +D GT+ C A
Sbjct: 1753 LDGGRFKISESEENDMYSLVISDLAMDDLGTYKCVA 1788



 Score =  105 bits (251), Expect = 1e-21
 Identities = 82/331 (24%), Positives = 144/331 (43%), Gaps = 39/331 (11%)

Query: 248  SDVQISTEI--DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
            SDV+I+ E   ++   PV   +I  KP   K +E     F+  ++  P  ++ W K+G+ 
Sbjct: 731  SDVKITIEPKKEKKQAPVFIHEIT-KPVVVKEKEQVKLVFEADVT--PDSKIEWLKDGKP 787

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
                 + +        TL +++T   D+G Y         C++ + Y    SP +     
Sbjct: 788  FTPDQRSDYTFDGRIITLMLKDTSVKDTGTYE--------CVIANKYGKCSSPVD----- 834

Query: 366  QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
                             +++  K L P+ V   ++ D  E    RF+  V+G P P+  W
Sbjct: 835  -----------------VKVEPKHLKPEAVTPMKNIDAVESGQARFEVEVSGSPEPKFEW 877

Query: 426  FINDRQIRDDYNHKIL-VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
            +    ++ D   HKI+   +   + L+I NV  +D G+   +  N +G T  +  L V E
Sbjct: 878  YHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAELKVKE 937

Query: 485  KEQVVAPKFVER-FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            KE  VAP+F++     ++V +G+ V  + +    P P++TW KDG  +  +  +     G
Sbjct: 938  KE--VAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRG 995

Query: 544  GASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
                L I ++   D   Y CTA N  G  ++
Sbjct: 996  DTYELVIKKSTPEDTGTYTCTATNNIGKCSS 1026



 Score =  104 bits (250), Expect = 2e-21
 Identities = 107/467 (22%), Positives = 190/467 (40%), Gaps = 52/467 (11%)

Query: 122  YNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI--QPEGXXXXXXXXXXXXXY 179
            Y+    ++ L  K     D G Y C   N++G++   V I  +P+               
Sbjct: 696  YSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITK 755

Query: 180  RHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL----LREVS 235
              V +  E      +   T  S    K+ +       + D     TF+ R+    L++ S
Sbjct: 756  PVVVKEKEQVKLVFEADVTPDS----KIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTS 811

Query: 236  FRESITKRYVGESDV-QISTEIDRSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNP 293
             +++ T   V  +   + S+ +D  + P    P+     +N    E   A+F+V++SG+P
Sbjct: 812  VKDTGTYECVIANKYGKCSSPVDVKVEPKHLKPEAVTPMKNIDAVESGQARFEVEVSGSP 871

Query: 294  RPRVTWFKNGQRLINSNKHEIITTHNHT--TLRVRNTQKSDSGHYTLLAENPNGCIVTSG 351
             P+  W+    +L +S+KH+II   +    TL + N   +D G Y          ++TS 
Sbjct: 872  EPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYK---------LITSN 922

Query: 352  YLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKV-CQDRDVTEGKMTR 410
                                T T + E    +++ EK +AP+F++   +  DV +G+   
Sbjct: 923  LAG-----------------TTTNKAE----LKVKEKEVAPEFIQTDTKPIDVEQGQDVT 961

Query: 411  FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARN 469
               ++  +P P+VTW  + + +    + +I+    G+ + L+I   T  D+G  TC A N
Sbjct: 962  ASFKIKSKPKPQVTWLKDGKTLSS--SKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATN 1019

Query: 470  KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
              G+ +    +NV  +    AP    +   + V E +   L  +  G P P I W KDG 
Sbjct: 1020 NIGKCSSDFTVNVKGE----APTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIKWFKDGE 1075

Query: 530  PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
            P+  +  ++   DG   TL        D   Y+    N  G+  T A
Sbjct: 1076 PVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSA 1122



 Score =  103 bits (247), Expect = 4e-21
 Identities = 57/197 (28%), Positives = 97/197 (49%), Gaps = 4/197 (2%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            T   I +  + + P+ V    D +  E +  RFD  + G P P V WF    +I D    
Sbjct: 1120 TSADIAVQRRNVKPEIVGKVHDIEALETEQARFDIPIKGYPKPVVEWFHGPTRILDGGRF 1179

Query: 439  KILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VER 496
            K+  +E  + ++L+I+++ + D G   CVA N +G+T  +  L+V  KE++  P+F  + 
Sbjct: 1180 KLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGKTTARANLDV--KEKMFQPEFDKDE 1237

Query: 497  FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
               + V++GE    +    G P P +TW KDG P+  +  ++  + G   ++ I R    
Sbjct: 1238 VEPIEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPE 1297

Query: 557  DAAWYQCTAQNVAGSTA 573
            DA  Y C A N +G  +
Sbjct: 1298 DAGTYMCEATNPSGKAS 1314



 Score =  103 bits (246), Expect = 5e-21
 Identities = 112/512 (21%), Positives = 193/512 (37%), Gaps = 42/512 (8%)

Query: 68   EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
            E +P   +   K     QG +     K++  P P V+W +    L    +        T 
Sbjct: 939  EVAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTY 998

Query: 128  DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET-V 186
            +  L+IK+  P D G YTCTA N  G+      +  +G                  +  +
Sbjct: 999  E--LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEAPTLSSKLQPVQVTEEDDCKL 1056

Query: 187  EHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVG 246
              K  G    T +  +  + V   +      T D K  T  ++ +      E   +    
Sbjct: 1057 TCKVSGLPEPTIKWFKDGEPVK--SDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNN 1114

Query: 247  ESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL 306
               V+ S +I      V P +I  K  + +  E   A+F + + G P+P V WF    R+
Sbjct: 1115 FGTVRTSADIAVQRRNVKP-EIVGKVHDIEALETEQARFDIPIKGYPKPVVEWFHGPTRI 1173

Query: 307  INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ 366
            ++               R + ++  ++  Y+L         V S  +  +  T   V + 
Sbjct: 1174 LDGG-------------RFKLSESEENDMYSL---------VISDLVMDDLGTYKCVANN 1211

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
                  D  +      +++ EK   P+F K   +  +V +G+       + G+P PEVTW
Sbjct: 1212 ------DAGKTTARANLDVKEKMFQPEFDKDEVEPIEVKQGEEASTSLVIRGKPKPEVTW 1265

Query: 426  FINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
            F + + +R+  N  I     G+ +++ I   +  D+G   C A N SG+ +    + +  
Sbjct: 1266 FKDGKPLRESKN--IQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKG 1323

Query: 485  KEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG 544
            +    AP F  +   + V E +   L  +  G P P I W KDG P+  +  ++   DG 
Sbjct: 1324 E----APTFASKLQPIQVTEEDECKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPTYDGK 1379

Query: 545  ASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
              TL        D   Y+    N  G+  T A
Sbjct: 1380 TCTLTFKGITMDDGGEYEVEVTNNFGTVRTSA 1411



 Score =  102 bits (245), Expect = 6e-21
 Identities = 53/199 (26%), Positives = 101/199 (50%), Gaps = 4/199 (2%)

Query: 379  TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
            T   +++ ++++ P+ +    D +  E +  +FD  + G P P V W+    +I D    
Sbjct: 1409 TSADVDVQKRSVKPEIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEWYHGPTRILDGGRF 1468

Query: 439  KILVNESGN-HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV-ER 496
            KI  +E  + ++L+I+N+ + D G   CVA N +G+     R+N+  KE++  P+F  + 
Sbjct: 1469 KISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKAT--ARVNLDVKEKMFQPEFDRDE 1526

Query: 497  FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
               + V++GE    +    G P P++TW KDG  +     +++ + G   ++ I R    
Sbjct: 1527 VEPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPD 1586

Query: 557  DAAWYQCTAQNVAGSTATR 575
            D   Y C A N AG+++ +
Sbjct: 1587 DVGTYMCEATNKAGTSSRK 1605



 Score = 99.5 bits (237), Expect = 6e-20
 Identities = 112/496 (22%), Positives = 192/496 (38%), Gaps = 43/496 (8%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGE 143
            QG  A     +RG P P V+W +   PL E      +     GD  S+ I +  P D G 
Sbjct: 1245 QGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQK---SIGDTYSIRIVRTSPEDAGT 1301

Query: 144  YTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSET-VEHKAYGTQGYTTEQSR 202
            Y C A N  G+A  +  I  +G                  E  +  K  G    T +  +
Sbjct: 1302 YMCEATNPSGKASKNFDIGIKGEAPTFASKLQPIQVTEEDECKLTCKVSGLPEPTIKWFK 1361

Query: 203  QTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262
              + V   +      T D K  T  ++ +      E   +       V+ S ++D     
Sbjct: 1362 DGEPVK--SDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRS 1419

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            V P +I  K  + +  E   AQF + + G P+P V W+    R+++  + +I        
Sbjct: 1420 VKP-EIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEWYHGPTRILDGGRFKI-------- 1470

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
                    S+S       EN    +V S  +  +  T   V         D  +      
Sbjct: 1471 --------SES------EENDMYSLVISNLIMDDLGTYKCVASN------DAGKATARVN 1510

Query: 383  IEISEKALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +++ EK   P+F +   +  +V +G+       + G+P P+VTW+ + + +R+  N + L
Sbjct: 1511 LDVKEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQ-L 1569

Query: 442  VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
            ++    +++ I   T  D G   C A NK+G ++ +  + V  +     PK       + 
Sbjct: 1570 MSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGE----GPKLASELQPMQ 1625

Query: 502  VREGEPVVLNARAV-GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
            V EG+   L+     GT  P I W KDG P+  +  ++    G    L++     +DA  
Sbjct: 1626 VTEGDDCKLSCNVTEGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGD 1685

Query: 561  YQCTAQNVAGSTATRA 576
            Y+    N  G+  + A
Sbjct: 1686 YEVEITNKFGTVKSSA 1701



 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 62/250 (24%), Positives = 112/250 (44%), Gaps = 15/250 (6%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            PEF     + +++ +G+ A    SL+  G     + WF +GK +  S  I+         
Sbjct: 1231 PEFDKDEVEPIEVKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYS 1288

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            + I+ T   D+GTY C ATN  G+A  +  +      KG+ P F + +Q I+  ++ +  
Sbjct: 1289 IRIVRTSPEDAGTYMCEATNPSGKASKNFDIGI----KGEAPTFASKLQPIQVTEEDE-C 1343

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C V  + +P +K  W+ +G+P++   RIK   D     L        D GEY     
Sbjct: 1344 KLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVT 1401

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287
            N +G   T A ++      V   S++P+ + K+ ++E+++  Q Q        P   +  
Sbjct: 1402 NNFGTVRTSADVD------VQKRSVKPEIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEW 1455

Query: 3288 IQDVTKLVEG 3297
                T++++G
Sbjct: 1456 YHGPTRILDG 1465



 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 77/330 (23%), Positives = 137/330 (41%), Gaps = 44/330 (13%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            PEF       +D+ +GQ     AS          + W  +GKT+ +S RI          
Sbjct: 942  PEFIQTDTKPIDVEQGQ--DVTASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYE 999

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I  +   D+GTY+C ATN  G+      +      KG+ P  ++ +Q ++ + +    
Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNV----KGEAPTLSSKLQPVQ-VTEEDDC 1054

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C V  + +P +K  W+ +G+P++   RIK   D     L        D GEY  +  
Sbjct: 1055 KLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVT 1112

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287
            N +G   T A I       V   +++P+ + K+ ++E+L+  Q +        P   +  
Sbjct: 1113 NNFGTVRTSADI------AVQRRNVKPEIVGKVHDIEALETEQARFDIPIKGYPKPVVEW 1166

Query: 3288 IQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYC 3347
                T++++G    F  +L   ++ D+                      + +VI D++  
Sbjct: 1167 FHGPTRILDG--GRF--KLSESEENDM----------------------YSLVISDLVM- 1199

Query: 3348 YEENSGEYECVATNKLGRDSTKANLKCTSK 3377
              ++ G Y+CVA N  G+ + +ANL    K
Sbjct: 1200 --DDLGTYKCVANNDAGKTTARANLDVKEK 1227



 Score = 83.0 bits (196), Expect = 5e-15
 Identities = 68/247 (27%), Positives = 106/247 (42%), Gaps = 19/247 (7%)

Query: 3043 DTGRPPEFTTVFKDIVDISEGQIAH-YEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVY 3101
            D  +PP FT+  K +      Q++  +EA L P       IE+  +GK  +        +
Sbjct: 643  DKQQPPTFTSEVKPVQANENEQVSVVFEADLTPDSK----IEFLKDGKPFKGDENSDYSF 698

Query: 3102 AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKS-KGQKPRFTTHIQNIEG 3160
                ++L        DSGTY C  TNK GQ+   VK+    K  K Q P F   I     
Sbjct: 699  DGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITKPVV 758

Query: 3161 LKDGQSAH--FECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHD 3218
            +K+ +     FE  V P    D KIEW  +G+P     R     D   + L +  T   D
Sbjct: 759  VKEKEQVKLVFEADVTP----DSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKD 814

Query: 3219 SGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPS 3278
            +G Y C   NKYG+  +   +       V  + L+P+++  ++ +++++  Q +     S
Sbjct: 815  TGTYECVIANKYGKCSSPVDVK------VEPKHLKPEAVTPMKNIDAVESGQARFEVEVS 868

Query: 3279 AEP-PKF 3284
              P PKF
Sbjct: 869  GSPEPKF 875



 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 98/394 (24%), Positives = 167/394 (42%), Gaps = 78/394 (19%)

Query: 1812 SQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPY 1871
            S  ++     +    S +  +  D+ +   +AP F ++L  P +++E       C++   
Sbjct: 1295 SPEDAGTYMCEATNPSGKASKNFDIGIK-GEAPTFASKLQ-PIQVTEEDECKLTCKVSGL 1352

Query: 1872 PDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
            P+P   ++W+ +G+ ++S  R + + D     L    +  +D GEY  +  NN G   +S
Sbjct: 1353 PEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTS 1410

Query: 1932 IRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTE 1991
              ++VQ +      S     + K+  +E       AV+      E+ QF  PIK      
Sbjct: 1411 ADVDVQKR------SVKPEIMGKVDDIE-------AVE-----TEQAQFDIPIK------ 1446

Query: 1992 GHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFK--TTYDFGYVALDILYAYAEDTGT 2049
            G+P        PV      VEWY     +  G RFK   + +    +L I     +D GT
Sbjct: 1447 GYP-------KPV------VEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGT 1493

Query: 2050 YMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRP 2109
            Y C A+N  G+A  T+ V +D K  ++    D   +            +PIE +Q G+  
Sbjct: 1494 YKCVASNDAGKA--TARVNLDVKEKMFQPEFDRDEV------------EPIEVKQ-GEE- 1537

Query: 2110 VFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVAL 2169
                A TSLE             ++    P +T  W+ +G+ +R     +        ++
Sbjct: 1538 ----ASTSLE-------------IQGKPKPKVT--WYKDGKVLRETRNIQLMSIGNTYSV 1578

Query: 2170 DILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
             I+ T  +D GTYMC+ATNK G +     +KV+G
Sbjct: 1579 TIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSG 1612



 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 119/484 (24%), Positives = 190/484 (39%), Gaps = 94/484 (19%)

Query: 3039 QPDDDTGRPPEFT-TVFKDIVDISEGQIAH-YEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
            +P  +  + P F   + K +V   + Q+   +EA + P       IEW  +GK      R
Sbjct: 738  EPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTPDSK----IEWLKDGKPFTPDQR 793

Query: 3097 IRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQ 3156
                +   ++ L +  T   D+GTY C   NK+G+    V ++   + K  KP   T ++
Sbjct: 794  SDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKV--EPKHLKPEAVTPMK 851

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV--SDFGFVVLDIAYT 3214
            NI+ ++ GQ A FE  V     P+ K EWYH    +  S + K +   D     L I   
Sbjct: 852  NIDAVESGQ-ARFEVEVS--GSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENV 908

Query: 3215 QNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTP 3274
               D G Y     N  G    +A +    K  V  E +Q D+    + ++  QG Q  T 
Sbjct: 909  DTTDGGLYKLITSNLAGTTTNKAELKVKEK-EVAPEFIQTDT----KPIDVEQG-QDVTA 962

Query: 3275 STPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF 3334
            S      PK       VT L +G++     R+VP                   G  Y   
Sbjct: 963  SFKIKSKPK-----PQVTWLKDGKTLSSSKRIVPT----------------VRGDTYE-- 999

Query: 3335 HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGL 3394
                   L I     E++G Y C ATN +G        KC+S   + +  + P  +   L
Sbjct: 1000 -------LVIKKSTPEDTGTYTCTATNNIG--------KCSSDFTVNVKGEAPT-LSSKL 1043

Query: 3395 EKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKV 3454
            + +Q  E+          ++ K    V  +P   I+  ++GE    + R+ PT       
Sbjct: 1044 QPVQVTEE----------DDCKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPT------- 1086

Query: 3455 EWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
               ++GK+          C   F  + +     +D GEY  +  NN+G   T+A + VQ 
Sbjct: 1087 ---YDGKT----------CTLTFKGITM-----DDGGEYEVQVTNNFGTVRTSADIAVQ- 1127

Query: 3515 KRNI 3518
            +RN+
Sbjct: 1128 RRNV 1131



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 52/214 (24%), Positives = 87/214 (40%), Gaps = 4/214 (1%)

Query: 364 QDQRSQYITDTQQRETEERIEI-SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPE 422
           +D+ S +    +  E   +++I  +K   P F    +     E +           P  +
Sbjct: 619 KDEVSSFKLGAKPGEYTLQLDIPKDKQQPPTFTSEVKPVQANENEQVSVVFEADLTPDSK 678

Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           + +  + +  + D N      +  N  L   N T  DSG   CV  NK G+++   ++ +
Sbjct: 679 IEFLKDGKPFKGDENSDYSF-DGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITI 737

Query: 483 I-EKEQVVAPKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH 540
             +KE+  AP F+   +  + V+E E V L   A  TP  +I W KDG P  P+      
Sbjct: 738 EPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTPDSKIEWLKDGKPFTPDQRSDYT 797

Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            DG   TL +      D   Y+C   N  G  ++
Sbjct: 798 FDGRIITLMLKDTSVKDTGTYECVIANKYGKCSS 831



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 56/202 (27%), Positives = 87/202 (43%), Gaps = 10/202 (4%)

Query: 3056 DIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF--GMVVLEILGT 3113
            D ++  E + A ++  +   G    V+EW++    I    R +   +    M  L I   
Sbjct: 1429 DDIEAVETEQAQFDIPI--KGYPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNL 1486

Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTT-HIQNIEGLKDGQSAHFECT 3172
               D GTY C A+N  G+A   V L+   K K  +P F    ++ IE +K G+ A     
Sbjct: 1487 IMDDLGTYKCVASNDAGKATARVNLDV--KEKMFQPEFDRDEVEPIE-VKQGEEASTSLE 1543

Query: 3173 VVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
            +     P  K+ WY +G+ +R +  I+ +S      + I  T   D G Y+C A NK G 
Sbjct: 1544 IQ--GKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGT 1601

Query: 3233 DFTRATINCYGKGGVYLESLQP 3254
               +  I   G+G      LQP
Sbjct: 1602 SSRKFDIKVSGEGPKLASELQP 1623



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 15/188 (7%)

Query: 3044 TGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF 3103
            +G  P+  +  + +  ++EG       + +  G    +I+WF +G+ +++ HRI+  Y  
Sbjct: 1611 SGEGPKLASELQPM-QVTEGDDCKLSCN-VTEGTTKPIIKWFKDGEPVKSDHRIKPSYYG 1668

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
               +L + G    D+G Y    TNK+G  + S  ++   + +  KP    ++ +IE ++ 
Sbjct: 1669 KTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDV--QRRNVKPEIVGNVDDIEAVET 1726

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD-----FGFVVLDIAYTQNHD 3218
             Q A F+ T+     P   +EWYH    +    R K         +  V+ D+A     D
Sbjct: 1727 EQ-ARFDITIKGYPKP--VVEWYHGPTRILDGGRFKISESEENDMYSLVISDLAM---DD 1780

Query: 3219 SGEYVCRA 3226
             G Y C A
Sbjct: 1781 LGTYKCVA 1788



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 57/210 (27%), Positives = 88/210 (41%), Gaps = 11/210 (5%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAF--GM 3105
            PE      DI +  E + A ++  +   G    V+EWF+    I    R +   +    M
Sbjct: 1133 PEIVGKVHDI-EALETEQARFDIPI--KGYPKPVVEWFHGPTRILDGGRFKLSESEENDM 1189

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTT-HIQNIEGLKDG 3164
              L I      D GTY C A N  G+      L+   K K  +P F    ++ IE +K G
Sbjct: 1190 YSLVISDLVMDDLGTYKCVANNDAGKTTARANLDV--KEKMFQPEFDKDEVEPIE-VKQG 1246

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            + A    ++V    P  ++ W+ +G+P+R S  I+  S      + I  T   D+G Y+C
Sbjct: 1247 EEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMC 1304

Query: 3225 RAYNKYGEDFTRATINCYGKGGVYLESLQP 3254
             A N  G+      I   G+   +   LQP
Sbjct: 1305 EATNPSGKASKNFDIGIKGEAPTFASKLQP 1334



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 46/196 (23%), Positives = 71/196 (36%), Gaps = 5/196 (2%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            ++ K  AP      Q   VTE    +  C+V+G P P + WF +   ++ D   K    +
Sbjct: 1030 VNVKGEAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIKWFKDGEPVKSDLRIKPTY-D 1088

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
                 L    +T+ D G       N  G       + V  +   V P+ V +   +   E
Sbjct: 1089 GKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRN--VKPEIVGKVHDIEALE 1146

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT--DGGASTLDIPRAKASDAAWYQ 562
             E    +    G P P + W      I+     ++    +    +L I      D   Y+
Sbjct: 1147 TEQARFDIPIKGYPKPVVEWFHGPTRILDGGRFKLSESEENDMYSLVISDLVMDDLGTYK 1206

Query: 563  CTAQNVAGSTATRARL 578
            C A N AG T  RA L
Sbjct: 1207 CVANNDAGKTTARANL 1222



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 90/382 (23%), Positives = 150/382 (39%), Gaps = 30/382 (7%)

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
            D PK++     PP F +++K     E+E V      +   D K  IE+ ++GK       
Sbjct: 639  DIPKDK---QQPPTFTSEVKPVQANENEQVSVVFEADLTPDSK--IEFLKDGKPFKGDEN 693

Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFT--KATISCKK----LPDIILQN 3931
                +D   + L       +DSG Y C   N  G+  +  K TI  KK     P  I + 
Sbjct: 694  SDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEI 753

Query: 3932 QVPRGMKRSEALTQM-EATIKKYTSEVYLTEDDLYDVDKKQ----PPRFVTQIQSQTSLV 3986
              P  +K  E +  + EA +   +   +L +   +  D++       R +T +   TS+ 
Sbjct: 754  TKPVVVKEKEQVKLVFEADVTPDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSV- 812

Query: 3987 EMETTKFECQLA-PVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSG- 4044
              +T  +EC +A   G  +  V+     K  L     TP+ +   V         E SG 
Sbjct: 813  -KDTGTYECVIANKYGKCSSPVDVKVEPKH-LKPEAVTPMKNIDAVESGQARFEVEVSGS 870

Query: 4045 -----EYLCRATNLYGMDETKAVIKTTGKP-GIVYDSQLPKHMKSIEKIREMEASWQVTP 4098
                 E+   +T L   D+ K +IK   KP   +    +      + K+     +   T 
Sbjct: 871  PEPKFEWYHGSTKLNDSDKHK-IIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTN 929

Query: 4099 EQVVEESKARCPPVFVSL-PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY 4157
            +  ++  +    P F+      + VE+G+      ++   PKP+V WL +G T+ +  R 
Sbjct: 930  KAELKVKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSSSKRI 989

Query: 4158 KLTYDG-MYHFDIPKTRQYDTG 4178
              T  G  Y   I K+   DTG
Sbjct: 990  VPTVRGDTYELVIKKSTPEDTG 1011



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 62/236 (26%), Positives = 97/236 (41%), Gaps = 39/236 (16%)

Query: 904  ESTQKPEFKTPIKD-QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            +  Q P F + +K  Q +  E     FEA L P  DS  ++E+LKDG+P +        F
Sbjct: 643  DKQQPPTFTSEVKPVQANENEQVSVVFEADLTP--DS--KIEFLKDGKPFKGDENSDYSF 698

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQY 1022
            +   + L+ K+ T  D+G Y C   N  GQ+++   +TI  KK+   + Q P  + +I  
Sbjct: 699  DGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKE---KKQAPVFIHEI-- 753

Query: 1023 LEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFN 1082
                     + +E+VK+                       FEA V P S     +EW  +
Sbjct: 754  ---TKPVVVKEKEQVKLV----------------------FEADVTPDS----KIEWLKD 784

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            GK  T   R     D   + L +     +D+G Y  V  N  G+      + VE +
Sbjct: 785  GKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK 840



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 3/109 (2%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            +QAP+F   +     + E + V L  + +    P+ KIEW K+G   T   R   TFD  
Sbjct: 744  KQAPVFIHEITKPVVVKEKEQVKLVFEAD--VTPDSKIEWLKDGKPFTPDQRSDYTFDGR 801

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHP 2747
            ++TL +      D+G Y C   N  G+  S   +K+E +H L  E++ P
Sbjct: 802  IITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPKH-LKPEAVTP 849



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 69/335 (20%), Positives = 132/335 (39%), Gaps = 35/335 (10%)

Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
           GE  +Q+    D+   P    ++  KP  +   E     F+  L+  P  ++ + K+G+ 
Sbjct: 632 GEYTLQLDIPKDKQQPPTFTSEV--KPVQANENEQVSVVFEADLT--PDSKIEFLKDGKP 687

Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
                  +      +  L  +N  + DSG Y  +  N +G   +   + +E   E   + 
Sbjct: 688 FKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKE---KK 744

Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTW 425
           Q   +I      E  + + + EK    + VK+  + DVT    ++ +    G+P      
Sbjct: 745 QAPVFI-----HEITKPVVVKEK----EQVKLVFEADVTPD--SKIEWLKDGKP------ 787

Query: 426 FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
           F  D++    ++ +I+        LM+ + ++ D+G   CV  NK G+ +    + V  K
Sbjct: 788 FTPDQRSDYTFDGRIIT-------LMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK 840

Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI--HTDG 543
              + P+ V     ++  E           G+P P+  W      +  + + +I    D 
Sbjct: 841 H--LKPEAVTPMKNIDAVESGQARFEVEVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDK 898

Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              TL I     +D   Y+    N+AG+T  +A L
Sbjct: 899 PLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAEL 933



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 61/246 (24%), Positives = 105/246 (42%), Gaps = 39/246 (15%)

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ-SAHFECTVVPVDDPDMKIEWYHNGQP 3191
            E +++L+ + K K Q P FT+ ++ ++  ++ Q S  FE  +     PD KIE+  +G+P
Sbjct: 633  EYTLQLD-IPKDKQQPPTFTSEVKPVQANENEQVSVVFEADLT----PDSKIEFLKDGKP 687

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251
             +         D   ++L        DSG Y C   NK+G+  +   I           +
Sbjct: 688  FKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKI-----------T 736

Query: 3252 LQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDD 3311
            ++P            +  ++Q P          + + ++  KLV      FEA + P   
Sbjct: 737  IEP------------KKEKKQAPVFIHEITKPVVVKEKEQVKLV------FEADVTP--- 775

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
             D K+EW  +GK      R     D  I+ L +     +++G YECV  NK G+ S+  +
Sbjct: 776  -DSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVD 834

Query: 3372 LKCTSK 3377
            +K   K
Sbjct: 835  VKVEPK 840



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 67/274 (24%), Positives = 114/274 (41%), Gaps = 49/274 (17%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHL--EATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
            + P F   +K  +  E   V +  EA LTP +    ++E+  +G+P +       ++D  
Sbjct: 646  QPPTFTSEVKPVQANENEQVSVVFEADLTPDS----KIEFLKDGKPFKGDENSDYSFDGR 701

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEK 2093
             + L    A  +D+GTY C  TN  G++  +S VK+         T++ ++ KK      
Sbjct: 702  NILLSFKNATQKDSGTYECVLTNKHGQS--SSDVKI---------TIEPKKEKK------ 744

Query: 2094 YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAH--FECRVEPINDPHLTIDWFHNGQK 2151
                         Q PVF+  +T    +KE ++    FE  V P +     I+W  +G+ 
Sbjct: 745  -------------QAPVFIHEITKPVVVKEKEQVKLVFEADVTPDSK----IEWLKDGKP 787

Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDT 2211
                 R   T D   + L +  T  +D+GTY C   NK G+  +   +KV          
Sbjct: 788  FTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPKH------ 841

Query: 2212 QHPNGLEKIRQLEA-QGHSTRIEVEEPKISPPRF 2244
              P  +  ++ ++A +    R EVE      P+F
Sbjct: 842  LKPEAVTPMKNIDAVESGQARFEVEVSGSPEPKF 875



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 70/312 (22%), Positives = 133/312 (42%), Gaps = 26/312 (8%)

Query: 89   AKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTA 148
            A+F+  ++G P PVV W      +++  ++ +  +E+    SL+I  +   D G Y C A
Sbjct: 1439 AQFDIPIKGYPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVA 1498

Query: 149  RNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTE-QSRQTQKV 207
             N  G+A   V +  +               R   E +E K       + E Q +   KV
Sbjct: 1499 SNDAGKATARVNLDVKEKMFQPEFD------RDEVEPIEVKQGEEASTSLEIQGKPKPKV 1552

Query: 208  A-YTNGTDHSSTDDFKV----DTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGP 262
              Y +G     T + ++    +T+   ++R           Y+ E+  +  T   +    
Sbjct: 1553 TWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTP---DDVGTYMCEATNKAGTSSRKFDIK 1609

Query: 263  VSP--PKIAQKPRNSKLQEGADAQFQVQLS-GNPRPRVTWFKNGQRLINSNKHEIITTHN 319
            VS   PK+A + +  ++ EG D +    ++ G  +P + WFK+G+ +   + H I  ++ 
Sbjct: 1610 VSGEGPKLASELQPMQVTEGDDCKLSCNVTEGTTKPIIKWFKDGEPV--KSDHRIKPSYY 1667

Query: 320  HTT--LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQR 377
              T  L +     +D+G Y +   N  G + +S  + V+      V+ +    + D +  
Sbjct: 1668 GKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQ---RRNVKPEIVGNVDDIEAV 1724

Query: 378  ETEE-RIEISEK 388
            ETE+ R +I+ K
Sbjct: 1725 ETEQARFDITIK 1736



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            +AP  S  L  ++  E  +  L C++  + + T  ++WF +G+P+K+  R +P Y+    
Sbjct: 1035 EAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTC 1092

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             L    +  +D G Y  Q TN  G   TS  + V
Sbjct: 1093 TLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAV 1126



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 49/167 (29%), Positives = 80/167 (47%), Gaps = 15/167 (8%)

Query: 1709 QAPVFTMPM-KDIRVAENQAAH--FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            QAPVF   + K + V E +     FEA + P  D K  +EWL++G P     R     D 
Sbjct: 745  QAPVFIHEITKPVVVKEKEQVKLVFEADVTP--DSK--IEWLKDGKPFTPDQRSDYTFDG 800

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
              + L +K  + +D+GTY C   N+ G+  +   + V+ K    L+ +  + ++ I  +E
Sbjct: 801  RIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK---HLKPEAVTPMKNIDAVE 857

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYP 1872
                 Q R +VEV+ +  P+F    +G TKL++    H   + E  P
Sbjct: 858  SG---QARFEVEVSGSPEPKF-EWYHGSTKLNDSDK-HKIIKAEDKP 899



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 39/121 (32%), Positives = 55/121 (45%), Gaps = 6/121 (4%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I    P F   L  P  V+E     L C++  + +PT  ++WF +G  V    R K  YD
Sbjct: 1321 IKGEAPTFASKLQ-PIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYD 1377

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS---DIVTDTQNEQAIEQI 1288
                 L     T  D GEY V   N+ G+  TSA V V +RS   +I+    + +A+E  
Sbjct: 1378 GKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMGKVDDIEAVETE 1437

Query: 1289 Q 1289
            Q
Sbjct: 1438 Q 1438



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 2/106 (1%)

Query: 1298 TKQVREDITVM-QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
            T   + DI V  + P+ +  L  ++  EG +  L C +   G     ++WF +G+P+K+ 
Sbjct: 1601 TSSRKFDIKVSGEGPKLASELQPMQVTEGDDCKLSCNVTE-GTTKPIIKWFKDGEPVKSD 1659

Query: 1357 HRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            HR +P+Y      L+L  V   D+G Y  + TN+ G   +S  + V
Sbjct: 1660 HRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDV 1705



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            +AP F+  L  I+  E     L C++  + + T  ++WF +G+P+K+  R +P Y+    
Sbjct: 1324 EAPTFASKLQPIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTC 1381

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             L    +  +D G Y  + TN  G   TS  + V
Sbjct: 1382 TLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDV 1415



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 7/119 (5%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP FI     P  + +GQ      +I+  P P  +V W  +GK L S  R   +      
Sbjct: 941  APEFIQTDTKPIDVEQGQDVTASFKIKSKPKP--QVTWLKDGKTLSSSKRIVPTVRGDTY 998

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
             L I     ED+G YTC A NN+G+  S   +NV+ +   +      S L+ +Q  E+D
Sbjct: 999  ELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEAPTL-----SSKLQPVQVTEED 1052



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 10/127 (7%)

Query: 1186 PPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSA 1245
            P  V+E  +  L C++  + +PT  ++WF +G  V    R K  YD     L     T  
Sbjct: 1045 PVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMD 1102

Query: 1246 DTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDI 1305
            D GEY V+  N+ G+  TSA +  ++R ++  +   +  +  I+ LE     T+Q R DI
Sbjct: 1103 DGGEYEVQVTNNFGTVRTSADI-AVQRRNVKPEIVGK--VHDIEALE-----TEQARFDI 1154

Query: 1306 TVMQAPQ 1312
             +   P+
Sbjct: 1155 PIKGYPK 1161



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 9/151 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP F   ++ I+V E        ++   G P+  ++W ++G P+++  R+   +D    
Sbjct: 1324 EAPTFASKLQPIQVTEEDECKLTCKVS--GLPEPTIKWFKDGEPVKSDLRIKPTYDGKTC 1381

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L  K +  +D G Y     N  G   TS+ + VQ K S++ E      + K+  +E   
Sbjct: 1382 TLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQ-KRSVKPE-----IMGKVDDIEAVE 1435

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
              Q + D+ +     P  +   +GPT++ +G
Sbjct: 1436 TEQAQFDIPIKGYPKP-VVEWYHGPTRILDG 1465



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 59/250 (23%), Positives = 105/250 (42%), Gaps = 44/250 (17%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            +AP   ++L  P +++E       C++   P+P   ++W+ +G+ ++S  R + + D   
Sbjct: 1035 EAPTLSSKLQ-PVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1091

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
              L    +  +D GEY  +  NN G   +S  + VQ      R +     + K+  +E  
Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQ------RRNVKPEIVGKVHDIE-- 1143

Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021
                      +   E+ +F  PIK      G+P        PV      VEW+     + 
Sbjct: 1144 ----------ALETEQARFDIPIK------GYP-------KPV------VEWFHGPTRIL 1174

Query: 2022 QGHRFK--TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDT 2079
             G RFK   + +    +L I     +D GTY C A N  G+  TT+   +D K  ++   
Sbjct: 1175 DGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGK--TTARANLDVKEKMFQPE 1232

Query: 2080 LDEQRLKKIQ 2089
             D+  ++ I+
Sbjct: 1233 FDKDEVEPIE 1242



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 30/104 (28%), Positives = 53/104 (50%), Gaps = 4/104 (3%)

Query: 2635 DTGVQ-QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            D G++ +AP F + L+   ++ E     L  +V    +P +K  WFK+G  + +  R+K 
Sbjct: 1318 DIGIKGEAPTFASKLQPI-QVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKP 1374

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            T+D    TL+   +  DD G Y  + TN  G   ++A + ++ R
Sbjct: 1375 TYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKR 1418



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 32/151 (21%), Positives = 67/151 (44%), Gaps = 9/151 (5%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +AP  +  ++ ++V E        ++   G P+  ++W ++G P+++  R+   +D    
Sbjct: 1035 EAPTLSSKLQPVQVTEEDDCKLTCKVS--GLPEPTIKWFKDGEPVKSDLRIKPTYDGKTC 1092

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
             L  K +  +D G Y  +  N  G   TS+ + VQ +      +     + K+  +E   
Sbjct: 1093 TLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRR------NVKPEIVGKVHDIEALE 1146

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
              Q R D+ +     P  +   +GPT++ +G
Sbjct: 1147 TEQARFDIPIKGYPKP-VVEWFHGPTRILDG 1176



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 56/229 (24%), Positives = 91/229 (39%), Gaps = 39/229 (17%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY--DFGY 2034
            KP+    + + E  E      +  +     P   VEW+     +  G RFK +   +   
Sbjct: 1132 KPEIVGKVHDIEALETEQARFDIPIKGYPKPV--VEWFHGPTRILDGGRFKLSESEENDM 1189

Query: 2035 VALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKY 2094
             +L I     +D GTY C A N  G+  TT+   +D K  ++    D+       E+E  
Sbjct: 1190 YSLVISDLVMDDLGTYKCVANNDAGK--TTARANLDVKEKMFQPEFDKD------EVE-- 1239

Query: 2095 ERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRA 2154
                PIE                   +K+G+ A     +     P +T  WF +G+ +R 
Sbjct: 1240 ----PIE-------------------VKQGEEASTSLVIRGKPKPEVT--WFKDGKPLRE 1274

Query: 2155 GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                +        ++ I+ T  ED+GTYMC+ATN  G+A     + + G
Sbjct: 1275 SKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKG 1323



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 32/107 (29%), Positives = 53/107 (49%), Gaps = 6/107 (5%)

Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028
            K + P F +++Q    + E +  K  C+++ + +P +K  WF +G+P+    R  P YD 
Sbjct: 1322 KGEAPTFASKLQP-IQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDG 1378

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETKA---VIKTTGKPGIV 4072
                + F  +  +D GEY    TN +G   T A   V K + KP I+
Sbjct: 1379 KTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIM 1425



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 43/144 (29%), Positives = 66/144 (45%), Gaps = 12/144 (8%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAH--FEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            E  Q P F   I   + +KE       FEA + P  DS  ++EWLKDG+P     R    
Sbjct: 742  EKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTP--DS--KIEWLKDGKPFTPDQRSDYT 797

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQ 1021
            F+   + L +K  +V D G Y C   N  G+ ++  ++  V  K +  E+  P  ++ I 
Sbjct: 798  FDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVK-VEPKHLKPEAVTP--MKNID 854

Query: 1022 YLEDASRYSKRTEEEVKITQKPRF 1045
             +E       R E EV  + +P+F
Sbjct: 855  AVESG---QARFEVEVSGSPEPKF 875



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMK 1773
            T P+ D+   ++  A F+ +      PK +V WL++G  + +S R+          L +K
Sbjct: 949  TKPI-DVEQGQDVTASFKIK----SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIK 1003

Query: 1774 YVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
               PED+GTYTC A N +G+  +  T+ V+ +A
Sbjct: 1004 KSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEA 1036



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 40/198 (20%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            ++W KDG PV++  RI   ++     LT K +T+ D G Y     N  G   TSA++  V
Sbjct: 1357 IKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVD-V 1415

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062
             K+ +  E    G ++ I+ +E               T++ +F  P+KG  K V      
Sbjct: 1416 QKRSVKPEIM--GKVDDIEAVE---------------TEQAQFDIPIKGYPKPV------ 1452

Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANR--IQTYHDFGYVALDIASVRAEDSGVYTVVA 1120
                          VEWY    +I    R  I    +    +L I+++  +D G Y  VA
Sbjct: 1453 --------------VEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVA 1498

Query: 1121 RNAAGEAQLSASMTVETR 1138
             N AG+A    ++ V+ +
Sbjct: 1499 SNDAGKATARVNLDVKEK 1516



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 45/143 (31%), Positives = 64/143 (44%), Gaps = 20/143 (13%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F S L  I   E D     C V    +PT+K  WF + +P+ S  R K T+D    +L  
Sbjct: 1328 FASKLQPIQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTF 1385

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQ--GKA-GLEAVEQAEE 2892
                 +D G Y  + TN+ G+  TS       D ++   +  P+  GK   +EAVE  E+
Sbjct: 1386 KGITMDDGGEYEVEVTNNFGTVRTS------ADVDVQKRSVKPEIMGKVDDIEAVE-TEQ 1438

Query: 2893 ARLAKGRRPSVPDTEYPKP--EW 2913
            A+        +P   YPKP  EW
Sbjct: 1439 AQF------DIPIKGYPKPVVEW 1455



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            I++  + + P+ V    D +  E +  RFD  + G P P V W+    +I D    KI  
Sbjct: 1703 IDVQRRNVKPEIVGNVDDIEAVETEQARFDITIKGYPKPVVEWYHGPTRILDGGRFKISE 1762

Query: 443  NESGN-HALMITNVTLSDSGVVTCVA 467
            +E  + ++L+I+++ + D G   CVA
Sbjct: 1763 SEENDMYSLVISDLAMDDLGTYKCVA 1788



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 60/214 (28%), Positives = 90/214 (42%), Gaps = 26/214 (12%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGG--FAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT 959
            V E    PEF       I +++G    A F+ + +P      +V WLKDG+ + +S RI 
Sbjct: 935  VKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIKSKP----KPQVTWLKDGKTLSSSKRIV 990

Query: 960  TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEK 1019
                     L IK  T  D G YTC A N IG+   S++ T+  K +    S     L+ 
Sbjct: 991  PTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKC--SSDFTVNVKGEAPTLSSK---LQP 1045

Query: 1020 IQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEW 1079
            +Q  E         E++ K+T K   L P        +G+    + R++P  D   T   
Sbjct: 1046 VQVTE---------EDDCKLTCKVSGL-PEPTIKWFKDGEPVKSDLRIKPTYD-GKTCTL 1094

Query: 1080 YFNGKQITSAN--RIQTYHDFGYV--ALDIASVR 1109
             F G  +       +Q  ++FG V  + DIA  R
Sbjct: 1095 TFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQR 1128



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 4/108 (3%)

Query: 2641 APIFT-THLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            AP F  T  K  D + +GQ V    +++ +  P  ++ W K+G TL++  R+  T     
Sbjct: 941  APEFIQTDTKPID-VEQGQDVTASFKIKSKPKP--QVTWLKDGKTLSSSKRIVPTVRGDT 997

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHP 2747
              L I     +D+G YTC ATN +G+  S  ++ ++     L   L P
Sbjct: 998  YELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEAPTLSSKLQP 1045



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 3/99 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP  ++ L+   ++ E     L  +V    +P +K  WFK+G  + +  R+K T+D   
Sbjct: 1035 EAPTLSSKLQPV-QVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKT 1091

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRH 2738
             TL+   +  DD G Y  + TN  G   ++A I ++ R+
Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRN 1130



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 10/142 (7%)

Query: 1171 EISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYY 1230
            ++S   P     L  P  V+EG +  L C +   G     ++WF +G  V    R K  Y
Sbjct: 1609 KVSGEGPKLASELQ-PMQVTEGDDCKLSCNVTE-GTTKPIIKWFKDGEPVKSDHRIKPSY 1666

Query: 1231 DFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQL 1290
                  L++   T AD G+Y V   N  G+  +SA + V  R+       N   IE ++ 
Sbjct: 1667 YGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRNVKPEIVGNVDDIEAVE- 1725

Query: 1291 LEDAARRTKQVREDITVMQAPQ 1312
                   T+Q R DIT+   P+
Sbjct: 1726 -------TEQARFDITIKGYPK 1740



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 6/102 (5%)

Query: 763 EEQTSQRPQFIRPLQDLGELQEGRNAH--FEAQLTPVSDPTMRVEWYKDGRPITASSRIT 820
           +++  Q P FI  +     ++E       FEA +TP S    ++EW KDG+P T   R  
Sbjct: 740 KKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTPDS----KIEWLKDGKPFTPDQRSD 795

Query: 821 SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             F+   ++L +     +D G+Y     NK G+  S   ++V
Sbjct: 796 YTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKV 837



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 6/107 (5%)

Query: 3969 KKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028
            K + P   +++Q    + E +  K  C+++ + +P +K  WF +G+P+    R  P YD 
Sbjct: 1033 KGEAPTLSSKLQP-VQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDG 1089

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYGMDETK---AVIKTTGKPGIV 4072
                + F  +  +D GEY  + TN +G   T    AV +   KP IV
Sbjct: 1090 KTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRNVKPEIV 1136



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 42/139 (30%), Positives = 62/139 (44%), Gaps = 16/139 (11%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITH 2837
            S L  +   E D+    C V    +PT+K  WF + +P+ S  R K T+D    +L    
Sbjct: 1041 SKLQPVQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKG 1098

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKA-GLEAVEQAEEARLA 2896
               +D G Y  + TN+ G+  TS  +     +N+        GK   +EA+E  E+AR  
Sbjct: 1099 ITMDDGGEYEVQVTNNFGTVRTSADI-AVQRRNV---KPEIVGKVHDIEALE-TEQARF- 1152

Query: 2897 KGRRPSVPDTEYPKP--EW 2913
                  +P   YPKP  EW
Sbjct: 1153 -----DIPIKGYPKPVVEW 1166



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 6/99 (6%)

Query: 1709 QAPVFTMPMKDIRVAENQAAH--FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            Q P FT  +K ++  EN+     FEA L P  D K  +E+L++G P +         D  
Sbjct: 646  QPPTFTSEVKPVQANENEQVSVVFEADLTP--DSK--IEFLKDGKPFKGDENSDYSFDGR 701

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             + L+ K    +DSGTY C   N+ G++ +   + ++ K
Sbjct: 702  NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPK 740



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 4/104 (3%)

Query: 1293 DAARRTKQVREDITV-MQAPQFSR-ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            DA + T +   D+   M  P+F +  +  IE  +G        ++  G     V WF +G
Sbjct: 1212 DAGKTTARANLDVKEKMFQPEFDKDEVEPIEVKQGEEASTSLVIR--GKPKPEVTWFKDG 1269

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEA 1394
            KP++     +     D  ++ ++   PED+G Y C+ATN  G+A
Sbjct: 1270 KPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKA 1313



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 11/153 (7%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G+ P F + L  ++ + E D     C+V  + +P  TI WF +G+ +++  R + T+D  
Sbjct: 1323 GEAPTFASKLQPIQ-VTEEDECKLTCKVSGLPEP--TIKWFKDGEPVKSDLRIKPTYDGK 1379

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225
               L       +D G Y  + TN  G      T++ +   ++   +  P  + K+  +EA
Sbjct: 1380 TCTLTFKGITMDDGGEYEVEVTNNFG------TVRTSADVDVQKRSVKPEIMGKVDDIEA 1433

Query: 2226 QGHSTRIEVEEPKISPPRFVTE-LRGTTHVFEG 2257
               + + + + P    P+ V E   G T + +G
Sbjct: 1434 V-ETEQAQFDIPIKGYPKPVVEWYHGPTRILDG 1465



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 3/106 (2%)

Query: 768  QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827
            + P F   LQ + ++ E        +++ + +PT  ++W+KDG P+ +  RI   ++   
Sbjct: 1324 EAPTFASKLQPI-QVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1380

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLG 873
             +L    +  +D G Y V   N  G   ++A + V  RS     +G
Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMG 1426



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 9/132 (6%)

Query: 3525 PKGMEGTID-KIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENS--SAHFECRL 3581
            PKG +     K+ A  G   T+    P+ +   PP FT+    +  +EN   S  FE  L
Sbjct: 616  PKGKDEVSSFKLGAKPG-EYTLQLDIPK-DKQQPPTFTSEVKPVQANENEQVSVVFEADL 673

Query: 3582 IPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA 3641
             P  DS  ++E+  +GKP           D   ++L      Q+D+G Y C  TN+HG++
Sbjct: 674  TP--DS--KIEFLKDGKPFKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQS 729

Query: 3642 TVSCKLQVKGRQ 3653
            +   K+ ++ ++
Sbjct: 730  SSDVKITIEPKK 741



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 8/147 (5%)

Query: 1149 GLYE---KTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMG 1205
            G YE     +H + S  V+   + ++  K  PVF+  ++ P  V E + + L    E   
Sbjct: 716  GTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITKPVVVKEKEQVKLV--FEADV 773

Query: 1206 DPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSA 1265
             P  ++EW  +G+  T   R    +D   + L +   +  DTG Y     N  G   +  
Sbjct: 774  TPDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPV 833

Query: 1266 IVRVIE---RSDIVTDTQNEQAIEQIQ 1289
             V+V     + + VT  +N  A+E  Q
Sbjct: 834  DVKVEPKHLKPEAVTPMKNIDAVESGQ 860



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 58/227 (25%), Positives = 90/227 (39%), Gaps = 37/227 (16%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            D+  E   +KP  VT  K+I+ V  GQ   FE ++    +   K EW+     +    + 
Sbjct: 834  DVKVEPKHLKPEAVTPMKNIDAVESGQ-ARFEVEVSGSPEP--KFEWYHGSTKLNDSDKH 890

Query: 1494 RPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLE 1553
            + I              AED  +YT    N+  TD    +L    T+++  +T N+A L+
Sbjct: 891  KIIK-------------AEDKPLYTLIIENVDTTDGGLYKLI---TSNLAGTTTNKAELK 934

Query: 1554 QIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEW 1613
                            V E         T  K +++++GQ      ++   S    +V W
Sbjct: 935  ----------------VKEKEVAPEFIQTDTKPIDVEQGQDVTASFKI--KSKPKPQVTW 976

Query: 1614 YHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
              + K L S  R   T       L I    PED+GTYTC A N +G+
Sbjct: 977  LKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGK 1023



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 43/163 (26%), Positives = 75/163 (46%), Gaps = 12/163 (7%)

Query: 2216 GLEKIRQLEAQGHSTR---IEVEEPKISPPRFVTELRGTTHVFEGK--TAHFECQVEPVH 2270
            GL K+      G +T    ++V+E +++P    T+ +    V +G+  TA F+ + +P  
Sbjct: 914  GLYKLITSNLAGTTTNKAELKVKEKEVAPEFIQTDTK-PIDVEQGQDVTASFKIKSKP-- 970

Query: 2271 DPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAI 2330
                ++ +  +GK L S+ R   T       L I+   PED G Y+  A N +G C+S  
Sbjct: 971  --KPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKCSS-- 1026

Query: 2331 SMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTR 2373
              TV  KG   + S + + ++   E +     K   +PEP  +
Sbjct: 1027 DFTVNVKGEAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIK 1069



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 2/94 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F ++++   V E +  +  C+V    +P   I+W+++G+ + S  R +  YD    +L
Sbjct: 1326 PTFASKLQPIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTL 1383

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
                +  +D GEY     N+FG   T A +  +K
Sbjct: 1384 TFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQK 1417



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 43/223 (19%)

Query: 2373 RQRPVFTQPLQNIDNIQ--EGQTAHFDCRLIPV-GDPTLKVEWFRNEKLIEDSSR--ITK 2427
            ++R V  + +  +D+I+  E + A FD   IP+ G P   VEW+     I D  R  I++
Sbjct: 1416 QKRSVKPEIMGKVDDIEAVETEQAQFD---IPIKGYPKPVVEWYHGPTRILDGGRFKISE 1472

Query: 2428 THDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKI 2487
            + +    S+ IS++  +D G Y C ASN  G+              + L+ +        
Sbjct: 1473 SEENDMYSLVISNLIMDDLGTYKCVASNDAGK----------ATARVNLDVK-------- 1514

Query: 2488 QKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYIN 2547
            +K+ QP      E DR+  +PI         E+ +G+ A     +   G P  +  WY +
Sbjct: 1515 EKMFQP------EFDRDEVEPI---------EVKQGEEASTSLEI--QGKPKPKVTWYKD 1557

Query: 2548 GVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G  L+     +        ++ I     +D G YMC+A N+AG
Sbjct: 1558 GKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAG 1600



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 12/168 (7%)

Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750
            K   P F  +++  I V E       C+V  + +PT++  WF +G P  +  R+    D 
Sbjct: 1322 KGEAPTFASKLQP-IQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDG 1378

Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810
                L    I   D GEY    TN +G+  T+A +      D+   S  P+ M   K+ +
Sbjct: 1379 KTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADV------DVQKRSVKPEIMG--KVDD 1430

Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKED 3858
            +E      A  + PI   P   +      T    +G RF+     + D
Sbjct: 1431 IEAVETEQAQFDIPIKGYPKPVVEWYHGPT-RILDGGRFKISESEEND 1477



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 10/124 (8%)

Query: 3416 KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDF 3475
            KG+AP F   L  I+   E E      +++   +P +K  W+ +G+ +K+  R +   D 
Sbjct: 1322 KGEAPTFASKLQPIQVTEEDE-CKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDG 1378

Query: 3476 GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKI 3535
                L       +D GEY     NN+G   T+A + VQ KR++  E      + G +D I
Sbjct: 1379 KTCTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQ-KRSVKPE------IMGKVDDI 1431

Query: 3536 AALE 3539
             A+E
Sbjct: 1432 EAVE 1435



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 2/101 (1%)

Query: 766  TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
            + + P+    LQ + ++ EG +      +T  +   + ++W+KDG P+ +  RI   +  
Sbjct: 1611 SGEGPKLASELQPM-QVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYG 1668

Query: 826  GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
                LN+  +   DAG Y V   NK G   S+A I V  R+
Sbjct: 1669 KTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN 1709



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 3/109 (2%)

Query: 3684 EITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            ++ I  +K  PP FT E+K  +   E   V      +    P  +I++  +G+PF     
Sbjct: 637  QLDIPKDKQQPPTFTSEVKP-VQANENEQVSVVFEADLT--PDSKIEFLKDGKPFKGDEN 693

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRD 3792
                 D   I L       +D+G Y C  TNK G +++  KIT   K++
Sbjct: 694  SDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKE 742



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 68/268 (25%), Positives = 100/268 (37%), Gaps = 47/268 (17%)

Query: 3684 EITIED--EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            +ITIE   EK   P F  EI   + V E   V      +    P  +I+W  +G+PF   
Sbjct: 734  KITIEPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVT--PDSKIEWLKDGKPFTPD 791

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQ 3801
             R     D   I L +     +D G Y C   NK+G         CS+  D+ +E   P+
Sbjct: 792  QRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGK--------CSSPVDVKVE---PK 840

Query: 3802 GMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKL 3861
             +  E +                   TP K I  +      ES   RFE  V    +PK 
Sbjct: 841  HLKPEAV-------------------TPMKNIDAV------ESGQARFEVEVSGSPEPK- 874

Query: 3862 RIEWYRNGKLLPSGHRYRTV--YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
              EWY     L    +++ +   D    +L I  V   D G Y     N  G    KA +
Sbjct: 875  -FEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAEL 933

Query: 3920 SCKK---LPDIILQNQVPRGMKRSEALT 3944
              K+    P+ I  +  P  +++ + +T
Sbjct: 934  KVKEKEVAPEFIQTDTKPIDVEQGQDVT 961



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 51/218 (23%), Positives = 87/218 (39%), Gaps = 36/218 (16%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            Q P F+  +  ++  E   V +        D   ++E+  +GKP K       +++   +
Sbjct: 646  QPPTFTSEVKPVQANENEQVSVVFEADLTPDS--KIEFLKDGKPFKGDENSDYSFDGRNI 703

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
             L   +   +DSG Y C  TN+ G++ +   + +  KK+   + Q P  + +I       
Sbjct: 704  LLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKE---KKQAPVFIHEI------- 753

Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVT 1488
                          KP  V   + ++ V       FE  + P  DS  K+EW K+G+P T
Sbjct: 754  -------------TKPVVVKEKEQVKLV-------FEADVTP--DS--KIEWLKDGKPFT 789

Query: 1489 IGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
               R     D   + L + D   +D+G Y C   N  G
Sbjct: 790  PDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYG 827



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 5/86 (5%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTHDFG 2432
            +P    P++NID ++ GQ A F+  +   G P  K EW+     + DS +  I K  D  
Sbjct: 843  KPEAVTPMKNIDAVESGQ-ARFEVEVS--GSPEPKFEWYHGSTKLNDSDKHKIIKAEDKP 899

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
              ++ I +V   D G+Y    SNL G
Sbjct: 900  LYTLIIENVDTTDGGLYKLITSNLAG 925



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 13/154 (8%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G+ P   + L  ++  +E D     C+V  + +P  TI WF +G+ +++  R + T+D  
Sbjct: 1034 GEAPTLSSKLQPVQVTEEDD-CKLTCKVSGLPEP--TIKWFKDGEPVKSDLRIKPTYDGK 1090

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEA 2225
               L       +D G Y  + TN  G    +  + V   RN+      P  + K+  +EA
Sbjct: 1091 TCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQ-RRNV-----KPEIVGKVHDIEA 1144

Query: 2226 -QGHSTRIEVEEPKISPPRFVTE-LRGTTHVFEG 2257
             +    R ++  P    P+ V E   G T + +G
Sbjct: 1145 LETEQARFDI--PIKGYPKPVVEWFHGPTRILDG 1176



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 32/105 (30%), Positives = 53/105 (50%), Gaps = 6/105 (5%)

Query: 2632 MFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691
            + +   +++AP FT+ L+   K   G+ V L  +V   +D   KI+ +K+G    +  RL
Sbjct: 6    LIIAPAIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL 63

Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
                D   + L+  +    DSG Y C  TN  G++ S A+I IE+
Sbjct: 64   ----DGENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEE 104



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 770  PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
            P+FI+      ++++G++    A     S P  +V W KDG+ +++S RI          
Sbjct: 942  PEFIQTDTKPIDVEQGQDV--TASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYE 999

Query: 830  LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            L I     ED G+YT  A N +G+  S  ++ V
Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNV 1032



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 5/101 (4%)

Query: 1726 QAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785
            Q       L+  G PK  V W ++G P+  S  +         ++ +   +PED+GTY C
Sbjct: 1245 QGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMC 1304

Query: 1786 RAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLED 1826
             A N  G+A  +  + ++ +A         S LQ IQ  E+
Sbjct: 1305 EATNPSGKASKNFDIGIKGEA-----PTFASKLQPIQVTEE 1340



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 33/152 (21%), Positives = 68/152 (44%), Gaps = 12/152 (7%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            + P F   LQ I   +E +     C++  + +PT  ++WF++ + ++   RI  T+D   
Sbjct: 1324 EAPTFASKLQPIQVTEEDE-CKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1380

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLE-- 2491
             ++T   +  +D G Y    +N  G               +Q  +  PE M K+  +E  
Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFG------TVRTSADVDVQKRSVKPEIMGKVDDIEAV 1434

Query: 2492 QPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523
            +  + + + P + + KP+  +   GP+ + +G
Sbjct: 1435 ETEQAQFDIPIKGYPKPV-VEWYHGPTRILDG 1465



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 3280 EPPKFITQIQDVTKLVEGQ-SAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG 3338
            +PP F ++++ V      Q S  FEA L P    D K+E+  +GK            D  
Sbjct: 646  QPPTFTSEVKPVQANENEQVSVVFEADLTP----DSKIEFLKDGKPFKGDENSDYSFDGR 701

Query: 3339 IVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
             ++L      +++SG YECV TNK G+ S+   +    K+
Sbjct: 702  NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKK 741



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 56/249 (22%), Positives = 106/249 (42%), Gaps = 44/249 (17%)

Query: 1026 ASRYSKRTEE-EVKITQK---PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYF 1081
            A++Y K +   +VK+  K   P  + P+K  + +  GQ A FE  V    +     EWY 
Sbjct: 823  ANKYGKCSSPVDVKVEPKHLKPEAVTPMKNIDAVESGQ-ARFEVEVSGSPEPKF--EWYH 879

Query: 1082 NGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSI 1141
               ++  +++    H           ++AED  +YT++  N                  +
Sbjct: 880  GSTKLNDSDK----HKI---------IKAEDKPLYTLIIEN------------------V 908

Query: 1142 DTSSIHRGLYEK-TRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECR 1200
            DT+    GLY+  T ++  +   +   +++E  +  P F+Q  + P  V +G+++    +
Sbjct: 909  DTTD--GGLYKLITSNLAGTTTNKAELKVKE-KEVAPEFIQTDTKPIDVEQGQDVTASFK 965

Query: 1201 LEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGS 1260
            ++    P  +V W  +G++++   R           L I  +T  DTG YT  A N++G 
Sbjct: 966  IK--SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGK 1023

Query: 1261 AHTSAIVRV 1269
              +   V V
Sbjct: 1024 CSSDFTVNV 1032



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 2/94 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P   ++++   V E +  +  C+V    +P   I+W+++G+ + S  R +  YD    +L
Sbjct: 1037 PTLSSKLQPVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTL 1094

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
                +  +D GEY  +  N+FG   T A I+ ++
Sbjct: 1095 TFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQR 1128



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 3/105 (2%)

Query: 1977 KPQFGKP-IKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            +P+F K  ++  EV +G       +L     P   V W+ +G+P+++    +        
Sbjct: 1230 QPEFDKDEVEPIEVKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTY 1287

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTL 2080
            ++ I+    ED GTYMC+ATN  G+A     + +  ++  +   L
Sbjct: 1288 SIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKGEAPTFASKL 1332



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 3/99 (3%)

Query: 2639 QQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            QQ P FT+ +K        ++  +    E    P+ KIE+ K+G           +FD  
Sbjct: 645  QQPPTFTSEVKPVQA---NENEQVSVVFEADLTPDSKIEFLKDGKPFKGDENSDYSFDGR 701

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             + LS  +    DSG Y C  TN  G++ S   I IE +
Sbjct: 702  NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPK 740



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 24/99 (24%), Positives = 48/99 (48%), Gaps = 3/99 (3%)

Query: 768  QRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGY 827
            + P     LQ + ++ E  +     +++ + +PT  ++W+KDG P+ +  RI   ++   
Sbjct: 1035 EAPTLSSKLQPV-QVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1091

Query: 828  VSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
             +L    +  +D G Y V+  N  G   ++A I V  R+
Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRRN 1130



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 2/113 (1%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E   +PEF     + I +K+G  A     +   G     V W KDG+P+  S  I   
Sbjct: 1224 VKEKMFQPEFDKDEVEPIEVKQGEEASTSLVIR--GKPKPEVTWFKDGKPLRESKNIQQK 1281

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014
                  ++ I   +  DAG Y C A N  G+A+ + ++ I  +    A    P
Sbjct: 1282 SIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKGEAPTFASKLQP 1334



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629
            V E   Q       ++ +E+K+G+ A     L+       +V W+ + KPL+      + 
Sbjct: 1224 VKEKMFQPEFDKDEVEPIEVKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQK 1281

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            +     ++ I+   PED+GTY C A N  G+A
Sbjct: 1282 SIGDTYSIRIVRTSPEDAGTYMCEATNPSGKA 1313



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 1310 APQFSRA-LHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            AP+F +     I+  +G +V    +++       +V W  +GK + +  R  P    D  
Sbjct: 941  APEFIQTDTKPIDVEQGQDVTASFKIK--SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTY 998

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             L +    PED+G YTC ATN +G+  +   + V
Sbjct: 999  ELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNV 1032



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 3/94 (3%)

Query: 3830 PKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P+FI T  K   VE+ + V    +++ K  PK ++ W ++GK L S  R           
Sbjct: 942  PEFIQTDTKPIDVEQGQDVTASFKIKSK--PKPQVTWLKDGKTLSSSKRIVPTVRGDTYE 999

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            L I     ED+G Y C A N+ G+  +  T++ K
Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVK 1033



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 32/155 (20%), Positives = 68/155 (43%), Gaps = 12/155 (7%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V  + P  +  LQ +  + E       C++  + +PT  ++WF++ + ++   RI  T+D
Sbjct: 1032 VKGEAPTLSSKLQPVQ-VTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYD 1088

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKL 2490
                ++T   +  +D G Y  + +N  G               +Q     PE + K+  +
Sbjct: 1089 GKTCTLTFKGITMDDGGEYEVQVTNNFG------TVRTSADIAVQRRNVKPEIVGKVHDI 1142

Query: 2491 E--QPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523
            E  +  + R + P + + KP+  +   GP+ + +G
Sbjct: 1143 EALETEQARFDIPIKGYPKPV-VEWFHGPTRILDG 1176



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 2/102 (1%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
            +P+F +   +  E+++G  A     L     P   V W+KDG+P+  S  I         
Sbjct: 1230 QPEFDKDEVEPIEVKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTY 1287

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTA 870
            S+ I+    EDAG+Y   A N  G+A     I +   +   A
Sbjct: 1288 SIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKGEAPTFA 1329



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 9/135 (6%)

Query: 3554 SGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG 3613
            SG  P+  +    + ++E       C +       + ++WF +G+P+ +  R+K      
Sbjct: 1611 SGEGPKLASELQPMQVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYGK 1669

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ 3673
              IL + GV   DAG Y  + TN+ G    S  + V+ R    ++P++  +     + I+
Sbjct: 1670 TCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN---VKPEIVGN----VDDIE 1722

Query: 3674 KLEETLHKREEITIE 3688
             + ET   R +ITI+
Sbjct: 1723 AV-ETEQARFDITIK 1736



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 1/98 (1%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P+    ++  +VTEG    L   +T      + ++W+ +G PV+  HR K +Y     
Sbjct: 1613 EGPKLASELQPMQVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYGKTC 1671

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
             L++      D G Y  + TN  G   +++ + V  ++
Sbjct: 1672 ILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN 1709



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 4/112 (3%)

Query: 1293 DAARRTKQVREDITV-MQAPQFSR-ALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNG 1350
            DA + T +V  D+   M  P+F R  +  IE  +G        +Q  G    +V W+ +G
Sbjct: 1501 DAGKATARVNLDVKEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQ--GKPKPKVTWYKDG 1558

Query: 1351 KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            K ++     +     +  ++ ++   P+D G Y C+ATN+ G +     ++V
Sbjct: 1559 KVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKV 1610



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 28/86 (32%), Positives = 36/86 (41%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            PD KIEW  +GK      R   T D   +TL L D   +D+G Y C   NK G+  +   
Sbjct: 775  PDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVD 834

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQ 3026
            V    K    E     K  + +E  Q
Sbjct: 835  VKVEPKHLKPEAVTPMKNIDAVESGQ 860



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARD 3764
            + V E       C+V  + +PT++  WF +G P  +  R+    D     L    I   D
Sbjct: 1046 VQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDD 1103

Query: 3765 AGEYTCRATNKWGSATTTAKI 3785
             GEY  + TN +G+  T+A I
Sbjct: 1104 GGEYEVQVTNNFGTVRTSADI 1124



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 26/108 (24%), Positives = 55/108 (50%), Gaps = 3/108 (2%)

Query: 1832 RREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH 1891
            R+ D++V+  + P+  ++L  P +++EG      C +       + ++W+ +G+ ++S H
Sbjct: 1604 RKFDIKVS-GEGPKLASELQ-PMQVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDH 1660

Query: 1892 RYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            R + S       L++  V   D+G+Y  +  N  G   SS  ++VQ +
Sbjct: 1661 RIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRR 1708



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/98 (23%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G  P F +    + ++E       C++  + + +  ++WF +G+P+ +  R+K   D   
Sbjct: 1323 GEAPTFASKLQPIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1380

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
              L   G+   D G Y  + TN  G    S  + V+ R
Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFGTVRTSADVDVQKR 1418



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 2/113 (1%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E   +PEF     + I +K+G  A     LE  G    +V W KDG+ +  +  I   
Sbjct: 1513 VKEKMFQPEFDRDEVEPIEVKQGEEA--STSLEIQGKPKPKVTWYKDGKVLRETRNIQLM 1570

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014
                  ++TI   T  D G Y C A N  G ++   ++ +  +   +A    P
Sbjct: 1571 SIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGEGPKLASELQP 1623



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 769  RPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
            +P+F R   +  E+++G  A    ++     P  +V WYKDG+ +  +  I  +      
Sbjct: 1519 QPEFDRDEVEPIEVKQGEEASTSLEIQ--GKPKPKVTWYKDGKVLRETRNIQLMSIGNTY 1576

Query: 829  SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVA 863
            S+ I+    +D G+Y   A NK G +     I+V+
Sbjct: 1577 SVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVS 1611



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 60/236 (25%), Positives = 99/236 (41%), Gaps = 47/236 (19%)

Query: 2229 STRIEVE-EPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQS 2287
            S+ ++V+ EPK   P  VT ++    V  G+ A FE +V    +P  + E+YH    L  
Sbjct: 830  SSPVDVKVEPKHLKPEAVTPMKNIDAVESGQ-ARFEVEVSGSPEP--KFEWYHGSTKLND 886

Query: 2288 AARFHI--TFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQ 2345
            + +  I    D    +L I++    D G Y +         TS ++ T T K  +     
Sbjct: 887  SDKHKIIKAEDKPLYTLIIENVDTTDGGLYKL--------ITSNLAGTTTNKAEL----- 933

Query: 2346 RPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQ--TAHFDCRLIPV 2403
                  K++E E A  F + +            T+P+    ++++GQ  TA F  +    
Sbjct: 934  ------KVKEKEVAPEFIQTD------------TKPI----DVEQGQDVTASFKIK---- 967

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
              P  +V W ++ K +  S RI  T       + I     ED G Y C A+N +G+
Sbjct: 968  SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGK 1023



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 7/120 (5%)

Query: 1546 TQNEAGLEQIQVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPV 1604
            T ++ G  +++V  +      +  VD +  +  P     + ++E  E ++A F+   IP+
Sbjct: 1389 TMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMGKVDDIEAVETEQAQFD---IPI 1445

Query: 1605 SDATLKV-EWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
                  V EWYH    +  G RF  +E+      +L I + + +D GTY C A N  G+A
Sbjct: 1446 KGYPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKA 1505



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 55/263 (20%), Positives = 101/263 (38%), Gaps = 15/263 (5%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            QG  A    +++G P P V+W +    L E     +     T  V+++  +  P D G Y
Sbjct: 1534 QGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTII--RTTPDDVGTY 1591

Query: 145  TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204
             C A N+ G +     I+  G                  +  +     T+G TT+   + 
Sbjct: 1592 MCEATNKAGTSSRKFDIKVSGEGPKLASELQPMQVTE-GDDCKLSCNVTEG-TTKPIIKW 1649

Query: 205  QKVAYTNGTDHSSTDDFKVDTFEYRL----LREVS-FRESITKRYVGESDVQISTEIDRS 259
             K      +DH     +   T    L    + +   +   IT ++     V+ S +ID  
Sbjct: 1650 FKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKF---GTVKSSADIDVQ 1706

Query: 260  LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
               V P +I     + +  E   A+F + + G P+P V W+    R+++  + +I  +  
Sbjct: 1707 RRNVKP-EIVGNVDDIEAVETEQARFDITIKGYPKPVVEWYHGPTRILDGGRFKISESEE 1765

Query: 320  HT--TLRVRNTQKSDSGHYTLLA 340
            +   +L + +    D G Y  +A
Sbjct: 1766 NDMYSLVISDLAMDDLGTYKCVA 1788



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 9/111 (8%)

Query: 755 KYQHQESIEEQTSQRPQF---IRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGR 811
           +Y  Q  I +   Q P F   ++P+Q      E  +  FEA LTP S    ++E+ KDG+
Sbjct: 633 EYTLQLDIPKDKQQPPTFTSEVKPVQ--ANENEQVSVVFEADLTPDS----KIEFLKDGK 686

Query: 812 PITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           P          F+   + L+  +   +D+G+Y     NK G++ S   I +
Sbjct: 687 PFKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITI 737



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 5/98 (5%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLK--STFDFGL 2699
            P   T +K+ D +  GQ  +   +VE    P  K EW+     L    + K     D  L
Sbjct: 844  PEAVTPMKNIDAVESGQARF---EVEVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPL 900

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             TL I ++   D G+Y    +NL G   + A +K++++
Sbjct: 901  YTLIIENVDTTDGGLYKLITSNLAGTTTNKAELKVKEK 938



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 41/145 (28%), Positives = 56/145 (38%), Gaps = 16/145 (11%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV-EWFHNGKPLLTGSRVKTIN--DFGF 3614
            PE      D+   E   A F+   IP+      V EWFH    +L G R K     +   
Sbjct: 1133 PEIVGKVHDIEALETEQARFD---IPIKGYPKPVVEWFHGPTRILDGGRFKLSESEENDM 1189

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL------PSHFKSG 3668
              L I  +   D G Y C A N  G+ T    L VK +   + +P+       P   K G
Sbjct: 1190 YSLVISDLVMDDLGTYKCVANNDAGKTTARANLDVKEK---MFQPEFDKDEVEPIEVKQG 1246

Query: 3669 TESIQKLEETLHKREEIT-IEDEKP 3692
             E+   L      + E+T  +D KP
Sbjct: 1247 EEASTSLVIRGKPKPEVTWFKDGKP 1271



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 21/76 (27%), Positives = 33/76 (43%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  ++ WF + KPL      +        S+ I  T  ED+G Y C+ATN  G A+ +  
Sbjct: 1259 PKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFD 1318

Query: 2863 LRCTGDKNIYFDTQHP 2878
            +   G+   +     P
Sbjct: 1319 IGIKGEAPTFASKLQP 1334



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F ++ + I+ V E       CK+  + +  +K  WFK+G+PV    R +P +D     
Sbjct: 1326 PTFASKLQPIQ-VTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCT 1382

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            L    +  +D G Y     N  GT   S
Sbjct: 1383 LTFKGITMDDGGEYEVEVTNNFGTVRTS 1410



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 1826 DSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            D+ +   R +++V      P F      P ++ +G+ A     I+  P P  +V WY +G
Sbjct: 1501 DAGKATARVNLDVKEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQGKPKP--KVTWYKDG 1558

Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
            KVL+     +  +     ++ I+    +D G Y C+A N  G +     + V  +
Sbjct: 1559 KVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGE 1613



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 2/91 (2%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+   E++  + V EG      C V   G     I WF +G P  +  R+          
Sbjct: 1615 PKLASELQP-MQVTEGDDCKLSCNVTE-GTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCI 1672

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L++D +   DAG+Y    TNK+G+  ++A I
Sbjct: 1673 LNLDGVTMADAGDYEVEITNKFGTVKSSADI 1703



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 43/161 (26%), Positives = 70/161 (43%), Gaps = 9/161 (5%)

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +SV L      K + P FT+ +Q     K G+       VV   D   KI+ Y +G+  +
Sbjct: 2    VSVSLIIAPAIK-KAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFK 58

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQ 3253
             + R+    D   ++L        DSG Y C   NKYG+  ++ATI  + +     E + 
Sbjct: 59   SNYRL----DGENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATI--FIEEEKKKEMIV 112

Query: 3254 PDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKL 3294
             D+  K  EL    GA  ++  T + +  +   +  +VT L
Sbjct: 113  TDTTFKPIELSLPFGAPDESVQTVAVDVKQIEKKPVEVTML 153



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 5/106 (4%)

Query: 3412 VEEEKGKAPVFTVPLSNIE-NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFR 3470
            + ++K + P FT  +  ++ N  E  +  FEA LTP      K+E+  +GK  K      
Sbjct: 640  IPKDKQQPPTFTSEVKPVQANENEQVSVVFEADLTPDS----KIEFLKDGKPFKGDENSD 695

Query: 3471 TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
               D   ++L       +DSG Y C   N +G++ +   + ++ K+
Sbjct: 696  YSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKK 741



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 8/137 (5%)

Query: 1826 DSSRYQRREDVEVAVNQ-APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            D+ +   R +++V      P F      P ++ +G+ A     I   P P   V W+ +G
Sbjct: 1212 DAGKTTARANLDVKEKMFQPEFDKDEVEPIEVKQGEEASTSLVIRGKPKPE--VTWFKDG 1269

Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            K L+     +  +     ++ I+    ED+G Y C+A N  G+A  +  + ++ +     
Sbjct: 1270 KPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASKNFDIGIKGEAPTF- 1328

Query: 1945 DSQHESALEKIQYLEDD 1961
                 S L+ IQ  E+D
Sbjct: 1329 ----ASKLQPIQVTEED 1341



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 15/128 (11%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRV-EWFHNGKPLLTGSRVKTIN--DFGF 3614
            PE      D+   E   A F+   IP+      V EW+H    +L G R K     +   
Sbjct: 1422 PEIMGKVDDIEAVETEQAQFD---IPIKGYPKPVVEWYHGPTRILDGGRFKISESEENDM 1478

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL------PSHFKSG 3668
              L I  +   D G Y C A+N  G+AT    L VK +   + +P+       P   K G
Sbjct: 1479 YSLVISNLIMDDLGTYKCVASNDAGKATARVNLDVKEK---MFQPEFDRDEVEPIEVKQG 1535

Query: 3669 TESIQKLE 3676
             E+   LE
Sbjct: 1536 EEASTSLE 1543



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 30/155 (19%), Positives = 65/155 (41%), Gaps = 8/155 (5%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHD 1764
            +V  + P     ++ ++V E          +  G  K  ++W ++G P+++ +R+   + 
Sbjct: 1609 KVSGEGPKLASELQPMQVTEGDDCKLSCN-VTEGTTKPIIKWFKDGEPVKSDHRIKPSYY 1667

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824
                 LN+  V   D+G Y     N+ G   +S+ + VQ +      +     +  +  +
Sbjct: 1668 GKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRR------NVKPEIVGNVDDI 1721

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEG 1859
            E     Q R D+ +     P  +   +GPT++ +G
Sbjct: 1722 EAVETEQARFDITIKGYPKP-VVEWYHGPTRILDG 1755



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 32/131 (24%), Positives = 60/131 (45%), Gaps = 6/131 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            PK  ++++   V E +  +  C V  +   K  I+W+++G+ + S HR +  Y      L
Sbjct: 1615 PKLASELQPMQVTEGDDCKLSCNVT-EGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCIL 1673

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKK---LPDIILQNQVPRGMKRSEALTQM 3946
            ++  V   D+G+Y     N FG   + A I  ++    P+I+        ++  +A  + 
Sbjct: 1674 NLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRNVKPEIVGNVDDIEAVETEQA--RF 1731

Query: 3947 EATIKKYTSEV 3957
            + TIK Y   V
Sbjct: 1732 DITIKGYPKPV 1742



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 19/59 (32%), Positives = 30/59 (50%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            ++W KDG PV++  RI   +      L +  VT+ DAG Y     N  G   +SA++ +
Sbjct: 1647 IKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDV 1705



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 35/157 (22%), Positives = 63/157 (40%), Gaps = 13/157 (8%)

Query: 1839 AVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND 1898
            A+ +AP F + L    K   G+      ++    D   +++ Y +GK+ +S +R    N 
Sbjct: 11   AIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRLDGEN- 67

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ---SKESIIRDSQHESALEKI 1955
                 L       +DSG Y C   N  G++ S   + ++    KE I+ D+  +     +
Sbjct: 68   ---IMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEKKKEMIVTDTTFKPIELSL 124

Query: 1956 QYLEDDSRYKRAVQDDSFVVEKP----QFGKPIKNAE 1988
             +   D   +    D   + +KP      GK +K  E
Sbjct: 125  PFGAPDESVQTVAVDVKQIEKKPVEVTMLGKEMKPVE 161



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 5/111 (4%)

Query: 2228 HSTRIEVEEPKISPPRFVTELRGT-THVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQ 2286
            ++ ++++ + K  PP F +E++    +  E  +  FE  + P    + +IEF  +GK  +
Sbjct: 634  YTLQLDIPKDKQQPPTFTSEVKPVQANENEQVSVVFEADLTP----DSKIEFLKDGKPFK 689

Query: 2287 SAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
                   +FD   + L  ++   +D+G Y     N  G  +S + +T+  K
Sbjct: 690  GDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPK 740



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 29/119 (24%), Positives = 57/119 (47%), Gaps = 9/119 (7%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F ++L+    V E       C+V  + +P   I+++ +G+ ++S  R   T+D    +
Sbjct: 1326 PTFASKLQ-PIQVTEEDECKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCT 1382

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360
            L  +    +D GEY V+  N  G      ++  +A   +   S +PE + K+ ++E+ E
Sbjct: 1383 LTFKGITMDDGGEYEVEVTNNFG------TVRTSADVDVQKRSVKPEIMGKVDDIEAVE 1435



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 31/135 (22%), Positives = 60/135 (44%), Gaps = 9/135 (6%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P+  +++Q    + E +  K  C +   G     ++WF +G+P+   +R  P Y      
Sbjct: 1615 PKLASELQPM-QVTEGDDCKLSCNVTE-GTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCI 1672

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEA 4092
            +N   V   D+G+Y    TN +G  ++ A I    +       ++  ++  IE +   +A
Sbjct: 1673 LNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN---VKPEIVGNVDDIEAVETEQA 1729

Query: 4093 SWQVT----PEQVVE 4103
             + +T    P+ VVE
Sbjct: 1730 RFDITIKGYPKPVVE 1744



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 6/99 (6%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF 3477
            KAP FT  L      + GE+     ++  T D   K++ Y +GK  K+  R     D   
Sbjct: 14   KAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL----DGEN 67

Query: 3478 VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKR 3516
            ++L       +DSG Y C   N YG++ + A++ ++ ++
Sbjct: 68   IMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEK 106



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 30/129 (23%), Positives = 56/129 (43%), Gaps = 8/129 (6%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            IE ++ K   P F+ E+     V E +      + +    P+ +IE+  +GK      R 
Sbjct: 737  IEPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVT--PDSKIEWLKDGKPFTPDQRS 794

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
              TFD   ++L ++    +D G Y     N  G C+S + + V  K        +PE + 
Sbjct: 795  DYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK------HLKPEAVT 848

Query: 2352 KIRELESAE 2360
             ++ +++ E
Sbjct: 849  PMKNIDAVE 857



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 7/88 (7%)

Query: 2775 VFISHLNN-IVCKEGDNIH--FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYV 2831
            VFI  +   +V KE + +   FE +V P      KIEW  + KP     R   T D   +
Sbjct: 748  VFIHEITKPVVVKEKEQVKLVFEADVTPDS----KIEWLKDGKPFTPDQRSDYTFDGRII 803

Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSATT 2859
            +L +  T  +D+G Y C   N  G  ++
Sbjct: 804  TLMLKDTSVKDTGTYECVIANKYGKCSS 831



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G  P  ++    + ++E       C++  + + +  ++WF +G+P+ +  R+K   D   
Sbjct: 1034 GEAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKT 1091

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
              L   G+   D G Y  + TN  G    S  + V+ R
Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRR 1129



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 37/186 (19%), Positives = 81/186 (43%), Gaps = 10/186 (5%)

Query: 2074 GLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRV 2133
            G+ +D   E  ++             ++ ++   +P  +  +  +E + E ++A F+  +
Sbjct: 1387 GITMDDGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMGKVDDIEAV-ETEQAQFDIPI 1445

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTH--DFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            +    P   ++W+H   +I  G R++ +   +    +L I     +D GTY C A+N  G
Sbjct: 1446 KGYPKP--VVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAG 1503

Query: 2192 EAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVE---EPKISPPRFVTEL 2248
            +A     L V     +       + +E I   + +  ST +E++   +PK++  +    L
Sbjct: 1504 KATARVNLDV--KEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVL 1561

Query: 2249 RGTTHV 2254
            R T ++
Sbjct: 1562 RETRNI 1567



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 21/79 (26%), Positives = 36/79 (45%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            +E  +G      +E +  PK ++ WY++GK+L      + +      S+ I+    +D G
Sbjct: 1530 IEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVG 1589

Query: 3901 EYICRAVNDFGEDFTKATI 3919
             Y+C A N  G    K  I
Sbjct: 1590 TYMCEATNKAGTSSRKFDI 1608



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491
            +++GE A     L     P  KV WY +GK L+     +         + I  T P+D G
Sbjct: 1532 VKQGEEA--STSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVG 1589

Query: 3492 EYLCRAYNNYGEAVTTASMKVQGK 3515
             Y+C A N  G +     +KV G+
Sbjct: 1590 TYMCEATNKAGTSSRKFDIKVSGE 1613



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/107 (24%), Positives = 46/107 (42%), Gaps = 6/107 (5%)

Query: 666 PTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAV 725
           P  KIEWLK+G+      R    F    I+L +   +++D+G Y C   +  G   +   
Sbjct: 775 PDSKIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVD 834

Query: 726 LHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQF 772
           + V P+         PE +  ++ ++     Q +  +E   S  P+F
Sbjct: 835 VKVEPK------HLKPEAVTPMKNIDAVESGQARFEVEVSGSPEPKF 875



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 1985 KNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYA 2044
            K  +V +G  V   A+    + P  +V W  +G+ +    R   T       L I  +  
Sbjct: 950  KPIDVEQGQDV--TASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTP 1007

Query: 2045 EDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
            EDTGTY C ATN +G+  +  +V V  ++
Sbjct: 1008 EDTGTYTCTATNNIGKCSSDFTVNVKGEA 1036



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1437 DESVTIKPRFVTRPKSIE--NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR 1494
            D +V +K    T    ++   V E       CK+  + +  +K  WFK+G+PV    R +
Sbjct: 1027 DFTVNVKGEAPTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIK 1084

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            P +D     L    +  +D G Y  +  N  GT   S
Sbjct: 1085 PTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTS 1121



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 39/163 (23%), Positives = 73/163 (44%), Gaps = 12/163 (7%)

Query: 1833 REDVEVAV---NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            R   ++AV   N  P  + +++    L E + A ++  I+ YP P   VEW+     +  
Sbjct: 1119 RTSADIAVQRRNVKPEIVGKVHDIEAL-ETEQARFDIPIKGYPKPV--VEWFHGPTRILD 1175

Query: 1890 GHRYRTSN--DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            G R++ S   +    +L I  +  +D G Y C A N+ G+  ++ R N+  KE + +   
Sbjct: 1176 GGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGK--TTARANLDVKEKMFQPEF 1233

Query: 1948 HESALEKIQYLEDDSRYKRAVQDDSFVVEKPQF--GKPIKNAE 1988
             +  +E I+  + +      V       E   F  GKP++ ++
Sbjct: 1234 DKDEVEPIEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESK 1276



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV-AMNFGWVYPEDSGEYLCRATNLYGMDET 4059
            G P  KV W+ +GK +L + R   +   G   ++      P+D G Y+C ATN  G    
Sbjct: 1546 GKPKPKVTWYKDGK-VLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSR 1604

Query: 4060 KAVIKTTGK 4068
            K  IK +G+
Sbjct: 1605 KFDIKVSGE 1613



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 7/97 (7%)

Query: 3824 PIVSTPPKFITQIKSHTVEE-SEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            P +   P F + ++     +  E V    +V    D K+ I  Y++GK+  S +R     
Sbjct: 10   PAIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSKIDI--YKDGKIFKSNYRL---- 63

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            D   + L      A+DSG Y C   N +G+  +KATI
Sbjct: 64   DGENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATI 100



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+   T   ++++G       +++    P +T  W  +G+ + +  R   T       
Sbjct: 942  PEFIQTDTKPIDVEQGQDVTASFKIKSKPKPQVT--WLKDGKTLSSSKRIVPTVRGDTYE 999

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
            L I  +  ED+GTY C ATN +G+  +  T+ V G
Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKG 1034



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 22/75 (29%), Positives = 35/75 (46%)

Query: 2385 IDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDE 2444
            ++ I+  Q       L+  G P  +V WF++ K + +S  I +       S+ I     E
Sbjct: 1238 VEPIEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPE 1297

Query: 2445 DEGVYMCRASNLLGE 2459
            D G YMC A+N  G+
Sbjct: 1298 DAGTYMCEATNPSGK 1312



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 2/84 (2%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491
            +++GE A     L     P  +V W+ +GK L+     +         + I  T PED+G
Sbjct: 1243 VKQGEEA--STSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAG 1300

Query: 3492 EYLCRAYNNYGEAVTTASMKVQGK 3515
             Y+C A N  G+A     + ++G+
Sbjct: 1301 TYMCEATNPSGKASKNFDIGIKGE 1324



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 5/103 (4%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRV-EPINDPHLTIDWFHNGQKIRAGHRYRTTHDF 2164
            G+ P   + L  ++ + EGD     C V E    P   I WF +G+ +++ HR + ++  
Sbjct: 1612 GEGPKLASELQPMQ-VTEGDDCKLSCNVTEGTTKP--IIKWFKDGEPVKSDHRIKPSYYG 1668

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
                L++      D+G Y  + TNK G   ++  + V   RN+
Sbjct: 1669 KTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQ-RRNV 1710



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 1/86 (1%)

Query: 2653 KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDS 2712
            ++ EG    L   V   T   + I+WFK+G  + +  R+K ++      L+++ +   D+
Sbjct: 1625 QVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADA 1683

Query: 2713 GIYTCKATNLLGEAVSTASIKIEDRH 2738
            G Y  + TN  G   S+A I ++ R+
Sbjct: 1684 GDYEVEITNKFGTVKSSADIDVQRRN 1709



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%)

Query: 1465 ECKLE-PVTDSNLK--VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
            +CKL   VT+   K  ++WFK+G+PV   HR +P +      L++  +   D+G Y    
Sbjct: 1631 DCKLSCNVTEGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEI 1690

Query: 1522 VNLVGT 1527
             N  GT
Sbjct: 1691 TNKFGT 1696



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P F + +Q   K   G+      ++V   D   K++ + +GK     +R     D   ++
Sbjct: 16   PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL----DGENIM 69

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            L       ++SG YEC+ TNK G+ S+KA +
Sbjct: 70   LTFKNASAKDSGTYECMVTNKYGKSSSKATI 100



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 2/98 (2%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            QAP FI ++  P  + E +        +  PD   ++EW  +GK      R   + D   
Sbjct: 745  QAPVFIHEITKPVVVKEKEQVKLVFEADVTPDS--KIEWLKDGKPFTPDQRSDYTFDGRI 802

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
              L +     +D+G Y C   N  G+  S + + V+ K
Sbjct: 803  ITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPK 840



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 28/134 (20%), Positives = 54/134 (40%), Gaps = 8/134 (5%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P F   L+ +   E  +     ++  + +PT+K  W K+G+ +++  R    +     +L
Sbjct: 1326 PTFASKLQPIQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTL 1383

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKY 756
                + + D GEY     +  G   T A + V      ++ S  PE +  +  +E     
Sbjct: 1384 TFKGITMDDGGEYEVEVTNNFGTVRTSADVDV------QKRSVKPEIMGKVDDIEAVETE 1437

Query: 757  QHQESIEEQTSQRP 770
            Q Q  I  +   +P
Sbjct: 1438 QAQFDIPIKGYPKP 1451



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 1/88 (1%)

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGE 2994
            +E +  P  K+ WY +GKVL +    +L S     ++ ++     D G Y C+A NK G 
Sbjct: 1542 LEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGT 1601

Query: 2995 AFTSSTVYCTSK-DNLIERTQHPKGTEG 3021
            +     +  + +   L    Q  + TEG
Sbjct: 1602 SSRKFDIKVSGEGPKLASELQPMQVTEG 1629



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 23/105 (21%), Positives = 53/105 (50%), Gaps = 7/105 (6%)

Query: 1707 ITQAPVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            I +AP FT  ++  ++    +      +++   D K+ +   ++G   +++ RL    D 
Sbjct: 12   IKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSKIDI--YKDGKIFKSNYRL----DG 65

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL 1810
              + L  K  + +DSGTY C   N+ G++ + +T+F++ +   ++
Sbjct: 66   ENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEKKKEM 110



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 55/218 (25%), Positives = 86/218 (39%), Gaps = 38/218 (17%)

Query: 1444 PRFVTRPKSIE-NVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            P F +  K ++ N  E   V FE  L P  DS  K+E+ K+G+P           D   +
Sbjct: 648  PTFTSEVKPVQANENEQVSVVFEADLTP--DS--KIEFLKDGKPFKGDENSDYSFDGRNI 703

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRS 1562
             L   +   +DSG Y C   N  G          +S++D+           +I +   + 
Sbjct: 704  LLSFKNATQKDSGTYECVLTNKHG----------QSSSDV-----------KITIEPKKE 742

Query: 1563 KYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKS 1622
            K      + E+T   P+       V+ KE  +  FE  + P S    K+EW  + KP   
Sbjct: 743  KKQAPVFIHEITK--PVV------VKEKEQVKLVFEADVTPDS----KIEWLKDGKPFTP 790

Query: 1623 GSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
              R   T +   + L +     +D+GTY C   N  G+
Sbjct: 791  DQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGK 828



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 10/124 (8%)

Query: 3547 TLTPEAESGNPPEFT---TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTG 3603
            T+ P+ E    P F    T P  +   E     FE  + P  DS  ++EW  +GKP    
Sbjct: 736  TIEPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTP--DS--KIEWLKDGKPFTPD 791

Query: 3604 SRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663
             R     D   + L +     +D G Y C   N++G+ +    ++V+ +    L+P+  +
Sbjct: 792  QRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKVEPKH---LKPEAVT 848

Query: 3664 HFKS 3667
              K+
Sbjct: 849  PMKN 852



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 637  PQFI-VPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
            P+FI    K +   +G  +    +I+    P  ++ WLK+G+++ +S R     R     
Sbjct: 942  PEFIQTDTKPIDVEQGQDVTASFKIK--SKPKPQVTWLKDGKTLSSSKRIVPTVRGDTYE 999

Query: 696  LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRA 732
            L +     +D+G YTC A +  G   +   ++V   A
Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGEA 1036



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 2/91 (2%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            EK   P F  +  + I+V +G        +   G P   + WF +G+P      +   + 
Sbjct: 1226 EKMFQPEFDKDEVEPIEVKQGEEASTSLVIR--GKPKPEVTWFKDGKPLRESKNIQQKSI 1283

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
                ++ I      DAG Y C ATN  G A+
Sbjct: 1284 GDTYSIRIVRTSPEDAGTYMCEATNPSGKAS 1314



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 2778 SHLNNIVCKEGDNIHFECNV-EPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            S L  +   EGD+    CNV E +  P +K  WF + +P+ S  R K ++      L++ 
Sbjct: 1619 SELQPMQVTEGDDCKLSCNVTEGTTKPIIK--WFKDGEPVKSDHRIKPSYYGKTCILNLD 1676

Query: 2837 HTYEEDSGIYTCKATNSKGSATTSGSL 2863
                 D+G Y  + TN  G+  +S  +
Sbjct: 1677 GVTMADAGDYEVEITNKFGTVKSSADI 1703



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P FT +++  +    G  V    +V    D   +ID + +G+ F +  R+   N    I 
Sbjct: 16   PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRLDGEN----IM 69

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            L      A+D+G Y C  TNK+G +++ A I
Sbjct: 70   LTFKNASAKDSGTYECMVTNKYGKSSSKATI 100



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 9/134 (6%)

Query: 1015 GGLEKIQYLEDASRYSKRTEEEVKITQ-KPRFLGPLKGTNKIVEGQ--SAHFEARVEPQS 1071
            GGL K+     A   + + E +VK  +  P F+        + +GQ  +A F+ + +P+ 
Sbjct: 913  GGLYKLITSNLAGTTTNKAELKVKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIKSKPKP 972

Query: 1072 DLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSA 1131
             +T    W  +GK ++S+ RI          L I     ED+G YT  A N  G+   S+
Sbjct: 973  QVT----WLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKC--SS 1026

Query: 1132 SMTVETRSSIDTSS 1145
              TV  +    T S
Sbjct: 1027 DFTVNVKGEAPTLS 1040



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 7/119 (5%)

Query: 1546 TQNEAGLEQIQVLEDRSKYHRT-DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPV 1604
            T ++ G  ++QV  +      + D+  +     P     + ++E  E ++A F+   IP+
Sbjct: 1100 TMDDGGEYEVQVTNNFGTVRTSADIAVQRRNVKPEIVGKVHDIEALETEQARFD---IPI 1156

Query: 1605 SDATLKV-EWYHNNKPLKSGSRF--TETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
                  V EW+H    +  G RF  +E+      +L I   + +D GTY C A N  G+
Sbjct: 1157 KGYPKPVVEWFHGPTRILDGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGK 1215



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 4/134 (2%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
            IVR++  +AG    +      K  +   +  +  +AP   + L+ +++ E        ++
Sbjct: 1291 IVRTSPEDAGTYMCEATNPSGKASKNFDIG-IKGEAPTFASKLQPIQVTEEDECKLTCKV 1349

Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
              + + T+K  W+ + +P+KS  R   T +     L       +D G Y     N  G  
Sbjct: 1350 SGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGTV 1407

Query: 1662 VTSGIAIVHSKKSI 1675
             TS    V  K+S+
Sbjct: 1408 RTSADVDV-QKRSV 1420



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 30/133 (22%), Positives = 55/133 (41%), Gaps = 4/133 (3%)

Query: 1007 IIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEAR 1066
            I+  S    G    +    + + SK  +  +K  + P F   L+   ++ E        +
Sbjct: 1291 IVRTSPEDAGTYMCEATNPSGKASKNFDIGIK-GEAPTFASKLQPI-QVTEEDECKLTCK 1348

Query: 1067 VEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGE 1126
            V    +   T++W+ +G+ + S  RI+  +D     L    +  +D G Y V   N  G 
Sbjct: 1349 VSGLPE--PTIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVEVTNNFGT 1406

Query: 1127 AQLSASMTVETRS 1139
             + SA + V+ RS
Sbjct: 1407 VRTSADVDVQKRS 1419



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/102 (24%), Positives = 53/102 (51%), Gaps = 13/102 (12%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDD-PDLKVEWFYNGKKLPHGHRYRTFHD---- 3336
            P+ + ++ D+ + VE + A F+   +P+   P   VEW++   ++  G R++        
Sbjct: 1422 PEIMGKVDDI-EAVETEQAQFD---IPIKGYPKPVVEWYHGPTRILDGGRFKISESEEND 1477

Query: 3337 -FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSK 3377
             + +VI +++    ++ G Y+CVA+N  G+ + + NL    K
Sbjct: 1478 MYSLVISNLIM---DDLGTYKCVASNDAGKATARVNLDVKEK 1516



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 9/98 (9%)

Query: 3558 PEFTTT---PSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-VKTINDFG 3613
            PEF  T   P D+   ++ +A F+ +  P      +V W  +GK L +  R V T+    
Sbjct: 942  PEFIQTDTKPIDVEQGQDVTASFKIKSKP----KPQVTWLKDGKTLSSSKRIVPTVRGDT 997

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            + ++ I      D G YTC ATN  G+ +    + VKG
Sbjct: 998  YELV-IKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKG 1034



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 18/59 (30%), Positives = 29/59 (49%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            ++  +    P  V   D +   E E ARF   + G+PKP V W      I++G R+K++
Sbjct: 1703 IDVQRRNVKPEIVGNVDDIEAVETEQARFDITIKGYPKPVVEWYHGPTRILDGGRFKIS 1761



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 4/94 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG--YI 694
           P+ + P+K++ A+E G+  FE  +E  G P  K EW      +  S +   I        
Sbjct: 844 PEAVTPMKNIDAVESGQARFE--VEVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLY 901

Query: 695 SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           +L + +++  D G Y     +  G    KA L V
Sbjct: 902 TLIIENVDTTDGGLYKLITSNLAGTTTNKAELKV 935



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 28/123 (22%), Positives = 50/123 (40%), Gaps = 3/123 (2%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
            I +ST  + G        +  K   +D    V  +AP  ++ L+ V++ E        ++
Sbjct: 1002 IKKSTPEDTGTYTCTATNNIGKCS-SDFTVNVKGEAPTLSSKLQPVQVTEEDDCKLTCKV 1060

Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
              + + T+K  W+ + +P+KS  R   T +     L       +D G Y  +  N  G  
Sbjct: 1061 SGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTV 1118

Query: 1662 VTS 1664
             TS
Sbjct: 1119 RTS 1121



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 29/130 (22%), Positives = 54/130 (41%), Gaps = 5/130 (3%)

Query: 2074 GLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRV 2133
            G+ +D   E  ++             I  ++   +P  +  +  +E L E ++A F+  +
Sbjct: 1098 GITMDDGGEYEVQVTNNFGTVRTSADIAVQRRNVKPEIVGKVHDIEAL-ETEQARFDIPI 1156

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTH--DFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            +    P   ++WFH   +I  G R++ +   +    +L I     +D GTY C A N  G
Sbjct: 1157 KGYPKP--VVEWFHGPTRILDGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAG 1214

Query: 2192 EAVNTCTLKV 2201
            +      L V
Sbjct: 1215 KTTARANLDV 1224



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 28/121 (23%), Positives = 50/121 (41%), Gaps = 3/121 (2%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            EK   P F  +  + I+V +G        ++  G P  ++ W+ +G+       +  ++ 
Sbjct: 1515 EKMFQPEFDRDEVEPIEVKQGEEASTSLEIQ--GKPKPKVTWYKDGKVLRETRNIQLMSI 1572

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK-RDIVLESQLPQGMSGEKI 3808
                ++ I      D G Y C ATNK G+++    I  S +   +  E Q  Q   G+  
Sbjct: 1573 GNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGEGPKLASELQPMQVTEGDDC 1632

Query: 3809 K 3809
            K
Sbjct: 1633 K 1633



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 22/82 (26%), Positives = 35/82 (42%)

Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            +E +  P  K+ W+K+G  L     ++        +++I     DD G Y C+ATN  G 
Sbjct: 1542 LEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGT 1601

Query: 2726 AVSTASIKIEDRHWLLGESLHP 2747
            +     IK+      L   L P
Sbjct: 1602 SSRKFDIKVSGEGPKLASELQP 1623



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 24/103 (23%), Positives = 50/103 (48%), Gaps = 6/103 (5%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            P   + P F + ++ Q+  K G       ++    DS  +++  KDG+  +++ R+    
Sbjct: 10   PAIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL---- 63

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKK 1005
            +   + LT K+ +  D+G Y C   N  G++++ A + I  +K
Sbjct: 64   DGENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEK 106



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 7/99 (7%)

Query: 1576 QAPICTTSLKN-VEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGF 1634
            +AP  T+ L+  V+ K G+      +++  SD+  K++ Y + K  KS  R    N    
Sbjct: 14   KAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRLDGEN---- 67

Query: 1635 VALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
            + L   +   +DSGTY C   N  G++ +     +  +K
Sbjct: 68   IMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEK 106



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 6/100 (6%)

Query: 1576 QAPICTTSLKNVEIKEGQRAH--FERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFG 1633
            Q P  T+ +K V+  E ++    FE  L P S    K+E+  + KP K       + +  
Sbjct: 646  QPPTFTSEVKPVQANENEQVSVVFEADLTPDS----KIEFLKDGKPFKGDENSDYSFDGR 701

Query: 1634 FVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
             + L   +   +DSGTY C   N  G++ +     +  KK
Sbjct: 702  NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKK 741



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 47/196 (23%), Positives = 74/196 (37%), Gaps = 11/196 (5%)

Query: 1142 DTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRL 1201
            DTS    G YE     +  K   P+    E    KP  V P+ N   V  G+       +
Sbjct: 809  DTSVKDTGTYECVIANKYGKCSSPVDVKVEPKHLKPEAVTPMKNIDAVESGQ---ARFEV 865

Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTY--YDFGFVALDIIHATSADTGEYTVRAVNHLG 1259
            E  G P  + EW+H    +    + K     D     L I +  + D G Y +   N  G
Sbjct: 866  EVSGSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAG 925

Query: 1260 SAHTSAIVRVIER----SDIVTDTQNEQAIEQIQLLEDAARRTKQVREDIT-VMQAPQFS 1314
            +    A ++V E+      I TDT+    +EQ Q +  + +   + +  +T +      S
Sbjct: 926  TTTNKAELKVKEKEVAPEFIQTDTKPID-VEQGQDVTASFKIKSKPKPQVTWLKDGKTLS 984

Query: 1315 RALHNIETVEGTNVHL 1330
             +   + TV G    L
Sbjct: 985  SSKRIVPTVRGDTYEL 1000



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 20/66 (30%), Positives = 31/66 (46%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  ++ W  + K L S  R   T       L I  +  ED+G YTC ATN+ G  ++  +
Sbjct: 970  PKPQVTWLKDGKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKCSSDFT 1029

Query: 2863 LRCTGD 2868
            +   G+
Sbjct: 1030 VNVKGE 1035



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/107 (23%), Positives = 51/107 (47%), Gaps = 8/107 (7%)

Query: 2254 VFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAG 2313
            V E       C+V  + +P   I+++ +G+ ++S  R   T+D    +L  +    +D G
Sbjct: 1048 VTEEDDCKLTCKVSGLPEPT--IKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGG 1105

Query: 2314 EYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360
            EY V+  N  G   ++  + V  +      + +PE + K+ ++E+ E
Sbjct: 1106 EYEVQVTNNFGTVRTSADIAVQRR------NVKPEIVGKVHDIEALE 1146



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 18/64 (28%), Positives = 32/64 (50%)

Query: 1076 TVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
            T++W+ +G+ + S  RI+  +D     L    +  +D G Y V   N  G  + SA + V
Sbjct: 1067 TIKWFKDGEPVKSDLRIKPTYDGKTCTLTFKGITMDDGGEYEVQVTNNFGTVRTSADIAV 1126

Query: 1136 ETRS 1139
            + R+
Sbjct: 1127 QRRN 1130



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 7/113 (6%)

Query: 1298 TKQVREDITVMQA---PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK 1354
            T +   DI V +    P+    +H+IE +E      +  ++  G     VEWF     I 
Sbjct: 1117 TVRTSADIAVQRRNVKPEIVGKVHDIEALETEQARFDIPIK--GYPKPVVEWFHGPTRIL 1174

Query: 1355 TGHRFR--PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
             G RF+   + E D  +L +  +  +D G Y C A N  G+      L V  K
Sbjct: 1175 DGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGKTTARANLDVKEK 1227



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 54/219 (24%), Positives = 90/219 (41%), Gaps = 42/219 (19%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPV-GDPTLKVEWFRNEKLIEDSSR--ITKTHDF 2431
            +P     + +I+ ++  Q A FD   IP+ G P   VEWF     I D  R  ++++ + 
Sbjct: 1132 KPEIVGKVHDIEALETEQ-ARFD---IPIKGYPKPVVEWFHGPTRILDGGRFKLSESEEN 1187

Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLE 2491
               S+ IS +  +D G Y C A+N  G+                L+ +        +K+ 
Sbjct: 1188 DMYSLVISDLVMDDLGTYKCVANNDAGKTTARA----------NLDVK--------EKMF 1229

Query: 2492 QPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVEL 2551
            QP      E D++  +PI         E+ +G+ A     +V  G P     W+ +G  L
Sbjct: 1230 QP------EFDKDEVEPI---------EVKQGEEA--STSLVIRGKPKPEVTWFKDGKPL 1272

Query: 2552 KMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +     +        ++ I      DAG YMC+A N +G
Sbjct: 1273 RESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSG 1311



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 2/68 (2%)

Query: 2672 PNLKIEWFKNGVTLTTGARLK--STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729
            P   +EWF     +  G R K   + +  + +L I+ L  DD G Y C A N  G+  + 
Sbjct: 1160 PKPVVEWFHGPTRILDGGRFKLSESEENDMYSLVISDLVMDDLGTYKCVANNDAGKTTAR 1219

Query: 2730 ASIKIEDR 2737
            A++ ++++
Sbjct: 1220 ANLDVKEK 1227



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 19/55 (34%), Positives = 25/55 (45%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            G P  +V WF +GKPL               ++      PED+G Y+C ATN  G
Sbjct: 1257 GKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSG 1311



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 6/113 (5%)

Query: 1719 DIRVAENQAAHFEARLIPV-GDPKLRVEWLRNGVPIEASNR--LTTMHDFGYVALNMKYV 1775
            DI   E + A F+   IP+ G PK  VEW      I    R  ++   +    +L +  +
Sbjct: 1430 DIEAVETEQAQFD---IPIKGYPKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNL 1486

Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
              +D GTY C A N+ G+A     L V+ K       + E    +++Q E++S
Sbjct: 1487 IMDDLGTYKCVASNDAGKATARVNLDVKEKMFQPEFDRDEVEPIEVKQGEEAS 1539



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/116 (21%), Positives = 51/116 (43%), Gaps = 3/116 (2%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            ++V+E K+  P F  +      V +G+ A    +++    P  ++ +Y +GK L+     
Sbjct: 1511 LDVKE-KMFQPEFDRDEVEPIEVKQGEEASTSLEIQG--KPKPKVTWYKDGKVLRETRNI 1567

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRP 2347
             +       S+ I    P+D G Y  +A N  G  +    + V+ +G  ++   +P
Sbjct: 1568 QLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGEGPKLASELQP 1623



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK +V W ++G  +  +  +  M      ++ +    P+D GTY C A N+ G   TS
Sbjct: 1546 GKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAG---TS 1602

Query: 1798 STLF 1801
            S  F
Sbjct: 1603 SRKF 1606



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 3/111 (2%)

Query: 1830 YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            Y  + D+     Q P F +++  P + +E +        +  PD   ++E+  +GK  + 
Sbjct: 634  YTLQLDIPKDKQQPPTFTSEVK-PVQANENEQVSVVFEADLTPDS--KIEFLKDGKPFKG 690

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
                  S D     L       +DSG Y C   N  GQ+ S +++ ++ K+
Sbjct: 691  DENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKK 741



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 5/111 (4%)

Query: 2093 KYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
            K   P  ++ E    +P  +T + +++ ++ G +A FE  VE    P    +W+H   K+
Sbjct: 828  KCSSPVDVKVEPKHLKPEAVTPMKNIDAVESG-QARFE--VEVSGSPEPKFEWYHGSTKL 884

Query: 2153 RAG--HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 H+     D     L I      D G Y    +N  G   N   LKV
Sbjct: 885  NDSDKHKIIKAEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAELKV 935



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 3/107 (2%)

Query: 3675 LEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
            L  T   + E+ +++++  P     + K  IDV +G  V    +++    P  ++ W  +
Sbjct: 923  LAGTTTNKAELKVKEKEVAPEFIQTDTKP-IDVEQGQDVTASFKIK--SKPKPQVTWLKD 979

Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
            G+  ++  R+          L I      D G YTC ATN  G  ++
Sbjct: 980  GKTLSSSKRIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIGKCSS 1026



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 2/95 (2%)

Query: 1432 KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH 1491
            K ++  +   + P F+       +V +GQ V    K++  +    +V W K+G+ ++   
Sbjct: 930  KAELKVKEKEVAPEFIQTDTKPIDVEQGQDVTASFKIK--SKPKPQVTWLKDGKTLSSSK 987

Query: 1492 RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            R  P        L I     ED+G YTC A N +G
Sbjct: 988  RIVPTVRGDTYELVIKKSTPEDTGTYTCTATNNIG 1022



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 2/68 (2%)

Query: 2672 PNLKIEWFKNGVTLTTGARLK--STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVST 2729
            P   +EW+     +  G R K   + +  + +L I++L  DD G Y C A+N  G+A + 
Sbjct: 1449 PKPVVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKATAR 1508

Query: 2730 ASIKIEDR 2737
             ++ ++++
Sbjct: 1509 VNLDVKEK 1516



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 7/119 (5%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSLD 2834
            +  +++I   E +   F+  ++    P   +EWF     +  G R+K   + +    SL 
Sbjct: 1136 VGKVHDIEALETEQARFDIPIKGYPKPV--VEWFHGPTRILDGGRFKLSESEENDMYSLV 1193

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
            I+    +D G Y C A N  G  T   +L     K   F  +  + +     V+Q EEA
Sbjct: 1194 ISDLVMDDLGTYKCVANNDAGKTTARANLDV---KEKMFQPEFDKDEVEPIEVKQGEEA 1249



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 3837 KSHTVE--ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR--TVYDMGFVSLDIL 3892
            K H +E  E+E  RF+  +  K  PK  +EW+     +  G R++     +    SL I 
Sbjct: 1138 KVHDIEALETEQARFDIPI--KGYPKPVVEWFHGPTRILDGGRFKLSESEENDMYSLVIS 1195

Query: 3893 YVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
             +  +D G Y C A ND G+   +A +  K+
Sbjct: 1196 DLVMDDLGTYKCVANNDAGKTTARANLDVKE 1226



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 21/79 (26%), Positives = 33/79 (41%)

Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
            R  P  ++ WFK+G  L     ++        ++ I     +D+G Y C+ATN  G+A  
Sbjct: 1256 RGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASK 1315

Query: 2729 TASIKIEDRHWLLGESLHP 2747
               I I+         L P
Sbjct: 1316 NFDIGIKGEAPTFASKLQP 1334



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 18/59 (30%), Positives = 29/59 (49%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            V+  K    P  +   D +   E E A+F   + G+PKP V W      I++G R+K++
Sbjct: 1413 VDVQKRSVKPEIMGKVDDIEAVETEQAQFDIPIKGYPKPVVEWYHGPTRILDGGRFKIS 1471



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 3278 SAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF 3337
            S E PK  +++Q + ++ EG        +       + ++WF +G+ +   HR +  +  
Sbjct: 1611 SGEGPKLASELQPM-QVTEGDDCKLSCNVTEGTTKPI-IKWFKDGEPVKSDHRIKPSYYG 1668

Query: 3338 GIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
               IL++      ++G+YE   TNK G   + A++
Sbjct: 1669 KTCILNLDGVTMADAGDYEVEITNKFGTVKSSADI 1703



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            + P FT+  +  V    G+       ++ T D    I+ + +GK  ++++R+        
Sbjct: 14   KAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSK--IDIYKDGKIFKSNYRLDGEN---- 67

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159
            ++L        DSGTY C  TNK+G++     +   ++ K +     T  + IE
Sbjct: 68   IMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEKKKEMIVTDTTFKPIE 121



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/102 (25%), Positives = 40/102 (39%), Gaps = 4/102 (3%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTK-FECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            +K+  P F   IQ+ T  +++E  +           P  +V W  +GK L    R  P  
Sbjct: 937  EKEVAPEF---IQTDTKPIDVEQGQDVTASFKIKSKPKPQVTWLKDGKTLSSSKRIVPTV 993

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGK 4068
                  +      PED+G Y C ATN  G   +   +   G+
Sbjct: 994  RGDTYELVIKKSTPEDTGTYTCTATNNIGKCSSDFTVNVKGE 1035



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 7/116 (6%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK--STHDFSYVSLDITH 2837
            +++I   E +   F+  ++    P   +EW+     +  G R+K   + +    SL I++
Sbjct: 1428 VDDIEAVETEQAQFDIPIKGYPKPV--VEWYHGPTRILDGGRFKISESEENDMYSLVISN 1485

Query: 2838 TYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEA 2893
               +D G Y C A+N  G AT   +L     K   F  +  + +     V+Q EEA
Sbjct: 1486 LIMDDLGTYKCVASNDAGKATARVNLDV---KEKMFQPEFDRDEVEPIEVKQGEEA 1538



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/90 (25%), Positives = 37/90 (41%), Gaps = 2/90 (2%)

Query: 1570 VDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTET 1629
            V E   Q       ++ +E+K+G+ A     +        KV WY + K L+        
Sbjct: 1513 VKEKMFQPEFDRDEVEPIEVKQGEEASTSLEI--QGKPKPKVTWYKDGKVLRETRNIQLM 1570

Query: 1630 NNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            +     ++ I+   P+D GTY C A N  G
Sbjct: 1571 SIGNTYSVTIIRTTPDDVGTYMCEATNKAG 1600



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 20/86 (23%), Positives = 39/86 (45%), Gaps = 2/86 (2%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            I  K+G+       ++    P  K+ W+ + K L      +     +  S+ I  T  +D
Sbjct: 1530 IEVKQGEEASTSLEIQGKPKP--KVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDD 1587

Query: 2843 SGIYTCKATNSKGSATTSGSLRCTGD 2868
             G Y C+ATN  G+++    ++ +G+
Sbjct: 1588 VGTYMCEATNKAGTSSRKFDIKVSGE 1613



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 31/138 (22%), Positives = 54/138 (39%), Gaps = 5/138 (3%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL-- 2962
            + ++ KPE + P+     +  GQ      +VE    P+ K EWY     L    + K+  
Sbjct: 838  EPKHLKPEAVTPMKNIDAVESGQARF---EVEVSGSPEPKFEWYHGSTKLNDSDKHKIIK 894

Query: 2963 TSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGL 3022
              D    TL + +V   D G+Y     N  G     + +    K+   E  Q       +
Sbjct: 895  AEDKPLYTLIIENVDTTDGGLYKLITSNLAGTTTNKAELKVKEKEVAPEFIQTDTKPIDV 954

Query: 3023 EKIQNLEDSLRKEPGQQP 3040
            E+ Q++  S + +   +P
Sbjct: 955  EQGQDVTASFKIKSKPKP 972



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 4/97 (4%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR--PAYEFDYV 1368
            P+    + +IE VE      +  ++  G     VEW+     I  G RF+   + E D  
Sbjct: 1422 PEIMGKVDDIEAVETEQAQFDIPIK--GYPKPVVEWYHGPTRILDGGRFKISESEENDMY 1479

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
            +L + ++  +D G Y C A+N  G+A     L V  K
Sbjct: 1480 SLVISNLIMDDLGTYKCVASNDAGKATARVNLDVKEK 1516



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP F   +K V A E  ++      E    P  KIE+LK+G+  +        F    I 
Sbjct: 647 PPTFTSEVKPVQANENEQV--SVVFEADLTPDSKIEFLKDGKPFKGDENSDYSFDGRNIL 704

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
           L   +   +DSG Y C   +  G + +   + + P+
Sbjct: 705 LSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPK 740



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 1434 DIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF 1493
            DI  +   +KP  V +   IE  +E +   F+  ++        VEWF     +  G RF
Sbjct: 1123 DIAVQRRNVKPEIVGKVHDIE-ALETEQARFDIPIKGYPKP--VVEWFHGPTRILDGGRF 1179

Query: 1494 R--PIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI-VRSTQNEA 1550
            +     +    +L I DL+ +D G Y C A N  G      + T R+  D+  +  Q E 
Sbjct: 1180 KLSESEENDMYSLVISDLVMDDLGTYKCVANNDAG------KTTARANLDVKEKMFQPEF 1233

Query: 1551 GLEQIQVLE 1559
              ++++ +E
Sbjct: 1234 DKDEVEPIE 1242



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P  KV W+ +GK L      +         + I+    ++ G Y C ATNK G  S K +
Sbjct: 1548 PKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFD 1607

Query: 3372 LKCTSKENLILDSQL 3386
            +K  S E   L S+L
Sbjct: 1608 IK-VSGEGPKLASEL 1621



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 6/85 (7%)

Query: 2373 RQRPVFTQPLQNIDNIQ--EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKT 2428
            ++R V  + + N+D+I+  E + A FD  +   G P   VEW+     I D  R  I+++
Sbjct: 1706 QRRNVKPEIVGNVDDIEAVETEQARFDITI--KGYPKPVVEWYHGPTRILDGGRFKISES 1763

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRA 2453
             +    S+ IS +  +D G Y C A
Sbjct: 1764 EENDMYSLVISDLAMDDLGTYKCVA 1788



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 7/94 (7%)

Query: 2500 EPDREFEK-PIFTQVLTGPSELWEGQHAH--YEARVVPVGDPSLRFEWYINGVELKMGSR 2556
            EP +E ++ P+F   +T P  + E +     +EA V P      + EW  +G       R
Sbjct: 738  EPKKEKKQAPVFIHEITKPVVVKEKEQVKLVFEADVTP----DSKIEWLKDGKPFTPDQR 793

Query: 2557 FRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
               T D   +TL +      D G Y C   N+ G
Sbjct: 794  SDYTFDGRIITLMLKDTSVKDTGTYECVIANKYG 827



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 21/95 (22%), Positives = 39/95 (41%), Gaps = 2/95 (2%)

Query: 637  PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
            P     L+ V   E        ++  + +PT+K  W K+G+ +++  R    +     +L
Sbjct: 1037 PTLSSKLQPVQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKTCTL 1094

Query: 697  DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
                + + D GEY  +  +  G   T A + V  R
Sbjct: 1095 TFKGITMDDGGEYEVQVTNNFGTVRTSADIAVQRR 1129



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            E P F +++Q + ++ E        ++  + +P +K  WF +G+ +    R +  +D   
Sbjct: 1324 EAPTFASKLQPI-QVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKT 1380

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L       ++ GEYE   TN  G   T A++
Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFGTVRTSADV 1413



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 5/91 (5%)

Query: 490 APKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL 548
           AP F       +  + GE V L  + V T   +I   KDG     N  L    DG    L
Sbjct: 15  APTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSKIDIYKDGKIFKSNYRL----DGENIML 70

Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
               A A D+  Y+C   N  G ++++A ++
Sbjct: 71  TFKNASAKDSGTYECMVTNKYGKSSSKATIF 101



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 18/72 (25%), Positives = 32/72 (44%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            +E  +G      +  +  PK  + W+++GK L      +        S+ I+    ED+G
Sbjct: 1241 IEVKQGEEASTSLVIRGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAG 1300

Query: 3901 EYICRAVNDFGE 3912
             Y+C A N  G+
Sbjct: 1301 TYMCEATNPSGK 1312



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K+ P F + +Q Q      E      ++    D   K++ + +GK  + K+ +    D  
Sbjct: 13   KKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGK--IFKSNYR--LDGE 66

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
             + + F     +DSG Y C  TN YG   +KA I
Sbjct: 67   NIMLTFKNASAKDSGTYECMVTNKYGKSSSKATI 100



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 9/106 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F + L      K G+      +V   +D    ID + +G+  ++ +R     D   + 
Sbjct: 16   PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSK--IDIYKDGKIFKSNYRL----DGENIM 69

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRN---IILDT 2211
            L      A+DSGTY C  TNK G++ +  T+ +   +    I+ DT
Sbjct: 70   LTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEKKKEMIVTDT 115



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 3/76 (3%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            PD KIE+  +GK  +       + D   + L   +  ++DSG Y C   NK G+  +SS 
Sbjct: 675  PDSKIEFLKDGKPFKGDENSDYSFDGRNILLSFKNATQKDSGTYECVLTNKHGQ--SSSD 732

Query: 3001 VYCTSKDNLIERTQHP 3016
            V  T +    E+ Q P
Sbjct: 733  VKITIEPKK-EKKQAP 747



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P F   L  P ++ E        +V  + +P+++  W+ +G  +K   R + T+D   
Sbjct: 1324 EAPTFASKLQ-PIQVTEEDECKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKT 1380

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             TL    +  +D G Y  +  N  G
Sbjct: 1381 CTLTFKGITMDDGGEYEVEVTNNFG 1405



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 6/128 (4%)

Query: 3391 EGGLEKLQTLEDSMVRRKDTSVEEEKGKA-PVFTVPLSNIENLREGENAHFEARLTPTDD 3449
            +GG  +++   +    R    V+ +K    P     + +IE + E E A F+  +     
Sbjct: 1392 DGGEYEVEVTNNFGTVRTSADVDVQKRSVKPEIMGKVDDIEAV-ETEQAQFDIPIKGYPK 1450

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFC--DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT 3507
            P   VEWY     +  G RF+     +     L IS    +D G Y C A N+ G+A   
Sbjct: 1451 P--VVEWYHGPTRILDGGRFKISESEENDMYSLVISNLIMDDLGTYKCVASNDAGKATAR 1508

Query: 3508 ASMKVQGK 3515
             ++ V+ K
Sbjct: 1509 VNLDVKEK 1516



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 4/61 (6%)

Query: 2942 DLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            D KI+ Y +GK+ +  S ++L  +   + L   +   +DSG Y C   NK G++ + +T+
Sbjct: 45   DSKIDIYKDGKIFK--SNYRLDGEN--IMLTFKNASAKDSGTYECMVTNKYGKSSSKATI 100

Query: 3002 Y 3002
            +
Sbjct: 101  F 101



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 2/84 (2%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F S +  +   E + +      E    P  KIE+  + KP         + D   + L  
Sbjct: 650  FTSEVKPVQANENEQVSVV--FEADLTPDSKIEFLKDGKPFKGDENSDYSFDGRNILLSF 707

Query: 2836 THTYEEDSGIYTCKATNSKGSATT 2859
             +  ++DSG Y C  TN  G +++
Sbjct: 708  KNATQKDSGTYECVLTNKHGQSSS 731



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 16/63 (25%), Positives = 29/63 (46%)

Query: 1343 RVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            ++EW  +GKP     R    ++   + L L     +D+G Y C   N+ G+  +   ++V
Sbjct: 778  KIEWLKDGKPFTPDQRSDYTFDGRIITLMLKDTSVKDTGTYECVIANKYGKCSSPVDVKV 837

Query: 1403 IAK 1405
              K
Sbjct: 838  EPK 840



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 4/71 (5%)

Query: 2522 EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFR--TTHDFGFVTLDINSVVANDAG 2579
            E   A +E  V   G P  +FEWY    +L    + +     D    TL I +V   D G
Sbjct: 857  ESGQARFEVEVS--GSPEPKFEWYHGSTKLNDSDKHKIIKAEDKPLYTLIIENVDTTDGG 914

Query: 2580 LYMCKAINRAG 2590
            LY     N AG
Sbjct: 915  LYKLITSNLAG 925



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/105 (21%), Positives = 49/105 (46%), Gaps = 3/105 (2%)

Query: 1036 EVKIT-QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQT 1094
            ++K++ + P+    L+   ++ EG        V  +      ++W+ +G+ + S +RI+ 
Sbjct: 1607 DIKVSGEGPKLASELQPM-QVTEGDDCKLSCNVT-EGTTKPIIKWFKDGEPVKSDHRIKP 1664

Query: 1095 YHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139
             +      L++  V   D+G Y V   N  G  + SA + V+ R+
Sbjct: 1665 SYYGKTCILNLDGVTMADAGDYEVEITNKFGTVKSSADIDVQRRN 1709



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 13/119 (10%)

Query: 4514 PSFTLTAQN-VNVTSGQLVRLDTKV--TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            P+FT   Q  V    G+ V L  KV  T    ID+Y  K+GK  + + R      DG   
Sbjct: 16   PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDSKIDIY--KDGKIFKSNYRL-----DGENI 68

Query: 4571 LLILE-AYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            +L  + A  +DSG YEC+  N  G++   ++  + +   K K    T     P E+  P
Sbjct: 69   MLTFKNASAKDSGTYECMVTNKYGKS--SSKATIFIEEEKKKEMIVTDTTFKPIELSLP 125



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P F   LQ   + + G +     ++   SD   +++ YKDG+   ++ R+        + 
Sbjct: 16  PTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRLDG----ENIM 69

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASI 860
           L   +  A+D+G+Y     NK G++ S A+I
Sbjct: 70  LTFKNASAKDSGTYECMVTNKYGKSSSKATI 100



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 5/137 (3%)

Query: 1041 QKPRFLGPLKGTNKIVEGQ-SAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFG 1099
            Q P F   +K        Q S  FEA + P S     +E+  +GK            D  
Sbjct: 646  QPPTFTSEVKPVQANENEQVSVVFEADLTPDSK----IEFLKDGKPFKGDENSDYSFDGR 701

Query: 1100 YVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEE 1159
             + L   +   +DSG Y  V  N  G++     +T+E +     + +      K   ++E
Sbjct: 702  NILLSFKNATQKDSGTYECVLTNKHGQSSSDVKITIEPKKEKKQAPVFIHEITKPVVVKE 761

Query: 1160 SKFVEPMYQIEEISKSK 1176
             + V+ +++ +    SK
Sbjct: 762  KEQVKLVFEADVTPDSK 778



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 3/112 (2%)

Query: 1176 KPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFV 1235
            +P F +    P  V +G+       LE  G P  +V W+ +G+ +      +        
Sbjct: 1519 QPEFDRDEVEPIEVKQGEEASTS--LEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTY 1576

Query: 1236 ALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI-ERSDIVTDTQNEQAIE 1286
            ++ II  T  D G Y   A N  G++     ++V  E   + ++ Q  Q  E
Sbjct: 1577 SVTIIRTTPDDVGTYMCEATNKAGTSSRKFDIKVSGEGPKLASELQPMQVTE 1628



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 2/91 (2%)

Query: 2911 PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVT 2970
            PE+I        + +GQ +    +++ K  P  ++ W  +GK L    R   T       
Sbjct: 942  PEFIQTDTKPIDVEQGQDVTASFKIKSKPKP--QVTWLKDGKTLSSSKRIVPTVRGDTYE 999

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            L +      D+G YTC A N  G+  +  TV
Sbjct: 1000 LVIKKSTPEDTGTYTCTATNNIGKCSSDFTV 1030



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 15/58 (25%), Positives = 28/58 (48%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEA 2995
            +  P  ++ W+ +GK L +    +  S     ++ +V     D+G Y C+A N  G+A
Sbjct: 1256 RGKPKPEVTWFKDGKPLRESKNIQQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKA 1313



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 17/72 (23%), Positives = 31/72 (43%)

Query: 658  TRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSAT 717
            T +E  G P  K+ W K+G+ +  +     +      S+ ++     D G Y C A +  
Sbjct: 1540 TSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKA 1599

Query: 718  GVAETKAVLHVT 729
            G +  K  + V+
Sbjct: 1600 GTSSRKFDIKVS 1611



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/90 (21%), Positives = 41/90 (45%), Gaps = 6/90 (6%)

Query: 2370 PVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH 2429
            P  ++ P FT  LQ     + G+      +++   D   K++ +++ K+ + + R+    
Sbjct: 10   PAIKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL---- 63

Query: 2430 DFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            D   + +T  +   +D G Y C  +N  G+
Sbjct: 64   DGENIMLTFKNASAKDSGTYECMVTNKYGK 93



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/101 (21%), Positives = 49/101 (48%), Gaps = 7/101 (6%)

Query: 1307 VMQAPQFSRALHN-IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
            + +AP F+  L   ++   G +V L  ++    D   +++ + +GK  K+ +R     + 
Sbjct: 12   IKKAPTFTSDLQQQVKAKLGEDVTLLFKVVTTSDS--KIDIYKDGKIFKSNYRL----DG 65

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
            + + L   +   +DSG Y C  TN+ G++ +   + +  +K
Sbjct: 66   ENIMLTFKNASAKDSGTYECMVTNKYGKSSSKATIFIEEEK 106



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 6/94 (6%)

Query: 2368 PEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGD--PTLKVEWFRNEKLIEDSSRI 2425
            P+   +Q PVF   +     ++E +      +L+   D  P  K+EW ++ K      R 
Sbjct: 739  PKKEKKQAPVFIHEITKPVVVKEKEQV----KLVFEADVTPDSKIEWLKDGKPFTPDQRS 794

Query: 2426 TKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
              T D   +++ +     +D G Y C  +N  G+
Sbjct: 795  DYTFDGRIITLMLKDTSVKDTGTYECVIANKYGK 828



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 4/79 (5%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFV 1635
            P    ++ ++E  E ++A F+  +         VEWYH    +  G RF  +E+      
Sbjct: 1712 PEIVGNVDDIEAVETEQARFDITIKGYPKPV--VEWYHGPTRILDGGRFKISESEENDMY 1769

Query: 1636 ALDIMSCLPEDSGTYTCRA 1654
            +L I     +D GTY C A
Sbjct: 1770 SLVISDLAMDDLGTYKCVA 1788



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 28/132 (21%), Positives = 62/132 (46%), Gaps = 16/132 (12%)

Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643
            V  S  +++ + +GK   +  R+   N    ++L       +D+G Y C  TN++G+++ 
Sbjct: 41   VTTSDSKIDIYKDGKIFKSNYRLDGEN----IMLTFKNASAKDSGTYECMVTNKYGKSSS 96

Query: 3644 SCKL---QVKGRQGIILEP-----QLPSHFKSGTESIQ----KLEETLHKREEITIEDEK 3691
               +   + K ++ I+ +      +L   F +  ES+Q     +++   K  E+T+  ++
Sbjct: 97   KATIFIEEEKKKEMIVTDTTFKPIELSLPFGAPDESVQTVAVDVKQIEKKPVEVTMLGKE 156

Query: 3692 PNPPRFTVEIKD 3703
              P  F +E +D
Sbjct: 157  MKPVEFKMEAQD 168



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 5/98 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR--VHTLNDFGF 3752
            P    ++ D I+  E     FD  ++  G P   ++WFH       G R  +    +   
Sbjct: 1133 PEIVGKVHD-IEALETEQARFDIPIK--GYPKPVVEWFHGPTRILDGGRFKLSESEENDM 1189

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
             +L I  +   D G Y C A N  G  T  A +    K
Sbjct: 1190 YSLVISDLVMDDLGTYKCVANNDAGKTTARANLDVKEK 1227



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/125 (23%), Positives = 50/125 (40%), Gaps = 7/125 (5%)

Query: 3530 GTIDKIAALEGYSGTVDTLTPEAESGNPPEFT---TTPSDLILSENSSAHFECRLIPVND 3586
            GT   +A+ +    T        E    PEF      P ++   E +S   E +  P   
Sbjct: 1492 GTYKCVASNDAGKATARVNLDVKEKMFQPEFDRDEVEPIEVKQGEEASTSLEIQGKP--- 1548

Query: 3587 SSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCK 3646
               +V W+ +GK L     ++ ++      + I      D G Y C+ATN+ G ++    
Sbjct: 1549 -KPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDDVGTYMCEATNKAGTSSRKFD 1607

Query: 3647 LQVKG 3651
            ++V G
Sbjct: 1608 IKVSG 1612



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P  +  L  P ++ E        +V  + +P+++  W+ +G  +K   R + T+D   
Sbjct: 1035 EAPTLSSKLQ-PVQVTEEDDCKLTCKVSGLPEPTIK--WFKDGEPVKSDLRIKPTYDGKT 1091

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             TL    +  +D G Y  +  N  G
Sbjct: 1092 CTLTFKGITMDDGGEYEVQVTNNFG 1116



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 31/142 (21%), Positives = 58/142 (40%), Gaps = 5/142 (3%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            ++V+E K+  P F  +      V +G+ A     +     P   + ++ +GK L+ +   
Sbjct: 1222 LDVKE-KMFQPEFDKDEVEPIEVKQGEEASTSLVIRG--KPKPEVTWFKDGKPLRESKNI 1278

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
                     S+ I    PEDAG Y  +A N  G  +   +  +  KG   + + + + ++
Sbjct: 1279 QQKSIGDTYSIRIVRTSPEDAGTYMCEATNPSGKASK--NFDIGIKGEAPTFASKLQPIQ 1336

Query: 2352 KIRELESAEPFKRPEIPEPVTR 2373
               E E     K   +PEP  +
Sbjct: 1337 VTEEDECKLTCKVSGLPEPTIK 1358



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 4118 DAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG-MYHFDIPKTRQYD 4176
            + + V++GE A     + G PKP+V W  +G  +      +L   G  Y   I +T   D
Sbjct: 1528 EPIEVKQGEEASTSLEIQGKPKPKVTWYKDGKVLRETRNIQLMSIGNTYSVTIIRTTPDD 1587

Query: 4177 TG 4178
             G
Sbjct: 1588 VG 1589



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 25/125 (20%), Positives = 52/125 (41%), Gaps = 6/125 (4%)

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
            I+R+T ++ G    +         R   + +V+ + P   + L+ +++ EG         
Sbjct: 1580 IIRTTPDDVGTYMCEATNKAGTSSRKFDI-KVSGEGPKLASELQPMQVTEGDDCKLSCN- 1637

Query: 1602 IPVSDATLK--VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
              V++ T K  ++W+ + +P+KS  R   +       L++      D+G Y     N  G
Sbjct: 1638 --VTEGTTKPIIKWFKDGEPVKSDHRIKPSYYGKTCILNLDGVTMADAGDYEVEITNKFG 1695

Query: 1660 EAVTS 1664
               +S
Sbjct: 1696 TVKSS 1700


>SB_26711| Best HMM Match : I-set (HMM E-Value=0)
          Length = 327

 Score =  153 bits (370), Expect = 4e-36
 Identities = 96/328 (29%), Positives = 157/328 (47%), Gaps = 21/328 (6%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P+ T K+      E ++A   V F G P P ++W+++   +K +      T  +   LII
Sbjct: 9    PVITSKLTRVECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLII 68

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            ++  + D   +  V  N  G+A  +A ++V E R +G G    P F    ++V V  G+ 
Sbjct: 69   QEAIINDEGSYRCVVRNELGSALSTAEVLVNE-REKGEG----PRFEERLRDVRVEIGR- 122

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED---GTYTLLILEAYPQDSGKYECV 4587
                 KV  + P +V W K  + +    R  I+++D   G + L I +  P+D G Y+CV
Sbjct: 123  -EASFKVRVSLPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCV 181

Query: 4588 AINSAGEARCDAECVVS-----LPATKDKPK--PQT-KAANAPPEIIEPLKDKIVAEGQA 4639
            A N  GE+ C A  ++       P   D+ +  P++ K     PEI++PLK+  V E   
Sbjct: 182  AFNEVGESSCKANLLLKEEEIVAPQVLDEVEAAPESSKQRGFAPEILQPLKEVNVPENDT 241

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
              F C++   P PTV+W +    +   +        +  TL I++A   D G YKCVA N
Sbjct: 242  AIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARN 301

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            + G ++ +AKL+V    + D    +TPL
Sbjct: 302  NFGDISTSAKLRVVVNSKPD---IITPL 326



 Score =  125 bits (301), Expect = 1e-27
 Identities = 98/325 (30%), Positives = 146/325 (44%), Gaps = 39/325 (12%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P  T     V    G    L  + TG+    V W K+G  ++P+ R     ++ + TL+I
Sbjct: 9    PVITSKLTRVECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLII 68

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
             EA   D G Y CV  N  G A   AE +V+     ++ K +       P   E L+D  
Sbjct: 69   QEAIINDEGSYRCVVRNELGSALSTAEVLVN-----EREKGEG------PRFEERLRDVR 117

Query: 4634 VAEGQAIEFSCKIVGKPLPT-VQWYKGDKLIKPSKYFQM-SRTADE--YTLRISEAFPED 4689
            V  G+   F  ++    LP  V W+KG+++I  +  F +    AD+  + L I +  PED
Sbjct: 118  VEIGREASFKVRV---SLPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPED 174

Query: 4690 EGDYKCVAYNSAGRVTVAAKL-----KVTQPDQADNLPA--------------LTPLRDI 4730
             G YKCVA+N  G  +  A L     ++  P   D + A              L PL+++
Sbjct: 175  LGVYKCVAFNEVGESSCKANLLLKEEEIVAPQVLDEVEAAPESSKQRGFAPEILQPLKEV 234

Query: 4731 VVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
             V E   A FK ++T+   PT++WLR+G  + E       +    A L I    + D G+
Sbjct: 235  NVPENDTAIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGS 294

Query: 4791 FTCRATTAAGQVETSAKL--VVKSK 4813
            + C A    G + TSAKL  VV SK
Sbjct: 295  YKCVARNNFGDISTSAKLRVVVNSK 319



 Score = 95.5 bits (227), Expect = 9e-19
 Identities = 88/336 (26%), Positives = 142/336 (42%), Gaps = 55/336 (16%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P I  K    +  EG  A   V+ +G+P P V WFK+G  L  +N+    T  +  TL +
Sbjct: 9   PVITSKLTRVECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLII 68

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
           +    +D G Y         C+V +   +  S  E  V ++                   
Sbjct: 69  QEAIINDEGSYR--------CVVRNELGSALSTAEVLVNER------------------- 101

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            EK   P+F +  +D  V  G+   F  RV+  P  EV WF  +  I D     I+ +++
Sbjct: 102 -EKGEGPRFEERLRDVRVEIGREASFKVRVS-LP-AEVDWFKGEEMIDDTGRFMIIDDDA 158

Query: 446 --GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV-------------- 489
             G   L I +V   D GV  CVA N+ GE++  C+ N++ KE+ +              
Sbjct: 159 DKGLFQLSIDDVRPEDLGVYKCVAFNEVGESS--CKANLLLKEEEIVAPQVLDEVEAAPE 216

Query: 490 -------APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542
                  AP+ ++    +NV E +  +   R   +P P + W +DGV +     +     
Sbjct: 217 SSKQRGFAPEILQPLKEVNVPENDTAIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYL 276

Query: 543 GGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              +TL I +A+ +D   Y+C A+N  G  +T A+L
Sbjct: 277 DEVATLTINQARDTDMGSYKCVARNNFGDISTSAKL 312



 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 75/312 (24%), Positives = 142/312 (45%), Gaps = 26/312 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  +  +EWF +G  ++ ++R+          L I      D G+Y C   N+ G A  
Sbjct: 33   TGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEGSYRCVVRNELGSALS 92

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            + ++   ++ KG+ PRF   ++++  ++ G+ A F+   V V  P  +++W+   + +  
Sbjct: 93   TAEVLVNEREKGEGPRFEERLRDVR-VEIGREASFK---VRVSLP-AEVDWFKGEEMIDD 147

Query: 3195 STRIKTV---SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251
            + R   +   +D G   L I   +  D G Y C A+N+ GE   +A +            
Sbjct: 148  TGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANL-----------L 196

Query: 3252 LQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDD 3311
            L+ + +   + L+ ++ A + +     A  P+ +  +++V  + E  +A F+ R+     
Sbjct: 197  LKEEEIVAPQVLDEVEAAPESSKQRGFA--PEILQPLKEV-NVPENDTAIFKCRVTA--S 251

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   VEW  +G ++  G R    +   +  L I    + + G Y+CVA N  G  ST A 
Sbjct: 252  PAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAK 311

Query: 3372 LK--CTSKENLI 3381
            L+    SK ++I
Sbjct: 312  LRVVVNSKPDII 323



 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 63/230 (27%), Positives = 99/230 (43%), Gaps = 23/230 (10%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT---ETNNF 1632
            + P     L++V ++ G+ A F+ R+        +V+W+   + +    RF    +  + 
Sbjct: 105  EGPRFEERLRDVRVEIGREASFKVRV----SLPAEVDWFKGEEMIDDTGRFMIIDDDADK 160

Query: 1633 GFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLE 1692
            G   L I    PED G Y C A N +GE+         S K+  L  + E   P++  L+
Sbjct: 161  GLFQLSIDDVRPEDLGVYKCVAFNEVGES---------SCKANLLLKEEEIVAPQV--LD 209

Query: 1693 DTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVP 1752
            +       S Q      AP    P+K++ V EN  A F+ R+     P   VEWLR+GV 
Sbjct: 210  EVEAAPESSKQRGF---APEILQPLKEVNVPENDTAIFKCRV--TASPAPTVEWLRDGVR 264

Query: 1753 IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            +    R+   +      L +      D G+Y C A N  G+  TS+ L V
Sbjct: 265  VTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRV 314



 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 67/242 (27%), Positives = 110/242 (45%), Gaps = 25/242 (10%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR---ITT 960
            E  + P F+  ++D + ++ G  A F+ R+    +    V+W K    ++ + R   I  
Sbjct: 102  EKGEGPRFEERLRD-VRVEIGREASFKVRVSLPAE----VDWFKGEEMIDDTGRFMIIDD 156

Query: 961  FFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI 1020
              + G   L+I  V   D G Y C A+N +G+++  ANL ++ +++I+A    P  L+++
Sbjct: 157  DADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANL-LLKEEEIVA----PQVLDEV 211

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            +   ++S+              P  L PLK  N + E  +A F+ RV        TVEW 
Sbjct: 212  EAAPESSKQRGFA---------PEILQPLKEVN-VPENDTAIFKCRVTASP--APTVEWL 259

Query: 1081 FNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
             +G ++T   RI   +      L I   R  D G Y  VARN  G+   SA + V   S 
Sbjct: 260  RDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSK 319

Query: 1141 ID 1142
             D
Sbjct: 320  PD 321



 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 68/241 (28%), Positives = 105/241 (43%), Gaps = 28/241 (11%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARL-IPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-- 1765
            + P F   ++D+RV   + A F+ R+ +P       V+W +    I+ + R   + D   
Sbjct: 105  EGPRFEERLRDVRVEIGREASFKVRVSLPA-----EVDWFKGEEMIDDTGRFMIIDDDAD 159

Query: 1766 -GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQL 1824
             G   L++  V PED G Y C A NE+GE+          KA+L L+ +   A Q + ++
Sbjct: 160  KGLFQLSIDDVRPEDLGVYKCVAFNEVGES--------SCKANLLLKEEEIVAPQVLDEV 211

Query: 1825 EDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNG 1884
            E +    ++         AP  +  L     + E  +A ++CR+   P P   VEW  +G
Sbjct: 212  EAAPESSKQRGF------APEILQPLK-EVNVPENDTAIFKCRVTASPAPT--VEWLRDG 262

Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS--IRLNVQSKESI 1942
              +  G R         A L I      D G Y C A NN G   +S  +R+ V SK  I
Sbjct: 263  VRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSKPDI 322

Query: 1943 I 1943
            I
Sbjct: 323  I 323



 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 70/252 (27%), Positives = 116/252 (46%), Gaps = 31/252 (12%)

Query: 3265 SLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARL-VPVDDPDLKVEWFYNGK 3323
            +L  A+         E P+F  +++DV ++  G+ A F+ R+ +P +     V+WF   +
Sbjct: 90   ALSTAEVLVNEREKGEGPRFEERLRDV-RVEIGREASFKVRVSLPAE-----VDWFKGEE 143

Query: 3324 KLPHGHRYRTFHDF---GIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
             +    R+    D    G+  L I     E+ G Y+CVA N++G  S KANL    KE  
Sbjct: 144  MIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLL--KEEE 201

Query: 3381 ILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHF 3440
            I+  Q+       L++++   +S          +++G AP    PL  + N+ E + A F
Sbjct: 202  IVAPQV-------LDEVEAAPES---------SKQRGFAPEILQPLKEV-NVPENDTAIF 244

Query: 3441 EARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNN 3500
            + R+T +  P   VEW  +G  +  G R           L I+     D G Y C A NN
Sbjct: 245  KCRVTASPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNN 302

Query: 3501 YGEAVTTASMKV 3512
            +G+  T+A ++V
Sbjct: 303  FGDISTSAKLRV 314



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 82/298 (27%), Positives = 119/298 (39%), Gaps = 34/298 (11%)

Query: 988  NAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLG 1047
            N +   T  ++ T++ ++ II +      + + +     S       E  K  + PRF  
Sbjct: 53   NRVSAETDESSCTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNEREK-GEGPRFEE 111

Query: 1048 PLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANR---IQTYHDFGYVALD 1104
             L+   ++  G+ A F+ RV     L   V+W+   + I    R   I    D G   L 
Sbjct: 112  RLRDV-RVEIGREASFKVRVS----LPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQLS 166

Query: 1105 IASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVE 1164
            I  VR ED GVY  VA N  GE+   A++ +                 K   I   + ++
Sbjct: 167  IDDVRPEDLGVYKCVAFNEVGESSCKANLLL-----------------KEEEIVAPQVLD 209

Query: 1165 PMYQIEEISKSK---PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221
             +    E SK +   P  +QPL     V E      +CR+     PT  VEW  +G  VT
Sbjct: 210  EVEAAPESSKQRGFAPEILQPLKEVN-VPENDTAIFKCRVTASPAPT--VEWLRDGVRVT 266

Query: 1222 VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS--DIVT 1277
             G R    Y      L I  A   D G Y   A N+ G   TSA +RV+  S  DI+T
Sbjct: 267  EGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSKPDIIT 324



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 70/260 (26%), Positives = 107/260 (41%), Gaps = 27/260 (10%)

Query: 3674 KLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH 3733
            +L   L   E +  E EK   PRF   ++D + V  G    F  RV    +    +DWF 
Sbjct: 86   ELGSALSTAEVLVNEREKGEGPRFEERLRD-VRVEIGREASFKVRVSLPAE----VDWFK 140

Query: 3734 NGRPFATGSRVHTLNDF---GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
                     R   ++D    G   L ID +   D G Y C A N+ G +        S K
Sbjct: 141  GEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGES--------SCK 192

Query: 3791 RDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE 3850
             +++L+ +  + ++ + + E+E      AP+        P+ +  +K   V E++   F+
Sbjct: 193  ANLLLKEE--EIVAPQVLDEVEA-----APESSKQRGFAPEILQPLKEVNVPENDTAIFK 245

Query: 3851 CRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910
            CRV     P   +EW R+G  +  G R    Y     +L I      D G Y C A N+F
Sbjct: 246  CRVTASPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNF 303

Query: 3911 GEDFT--KATISCKKLPDII 3928
            G+  T  K  +     PDII
Sbjct: 304  GDISTSAKLRVVVNSKPDII 323



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 66/256 (25%), Positives = 102/256 (39%), Gaps = 30/256 (11%)

Query: 3544 TVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTG 3603
            T + L  E E G  P F     D+ +     A F+ R+         V+WF   + +   
Sbjct: 93   TAEVLVNEREKGEGPRFEERLRDVRVEIGREASFKVRV----SLPAEVDWFKGEEMIDDT 148

Query: 3604 SRVKTINDF---GFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             R   I+D    G   L I  V   D G+Y C A N  GE+  SCK  +  ++  I+ PQ
Sbjct: 149  GRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGES--SCKANLLLKEEEIVAPQ 206

Query: 3661 LPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVE 3720
            +    ++  ES                  ++   P     +K+ ++VPE     F CRV 
Sbjct: 207  VLDEVEAAPES----------------SKQRGFAPEILQPLKE-VNVPENDTAIFKCRV- 248

Query: 3721 PVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
                P   ++W  +G     G R+          L I+     D G Y C A N +G  +
Sbjct: 249  -TASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDIS 307

Query: 3781 TTAK--ITCSAKRDIV 3794
            T+AK  +  ++K DI+
Sbjct: 308  TSAKLRVVVNSKPDII 323



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 54/205 (26%), Positives = 85/205 (41%), Gaps = 17/205 (8%)

Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTGAR---LKSTFDFGLVTLSINSLRNDDSGIYTCKA 2719
            EA  + R     +++WFK    +    R   +    D GL  LSI+ +R +D G+Y C A
Sbjct: 123  EASFKVRVSLPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVA 182

Query: 2720 TNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISH 2779
             N +GE+   A++ +++      E + P  LD + A                     +  
Sbjct: 183  FNEVGESSCKANLLLKEE-----EIVAPQVLDEVEA-------APESSKQRGFAPEILQP 230

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L  +   E D   F+C V  S  PT  +EW  +   +  G R  + +     +L I    
Sbjct: 231  LKEVNVPENDTAIFKCRVTASPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQAR 288

Query: 2840 EEDSGIYTCKATNSKGSATTSGSLR 2864
            + D G Y C A N+ G  +TS  LR
Sbjct: 289  DTDMGSYKCVARNNFGDISTSAKLR 313



 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 51/205 (24%), Positives = 92/205 (44%), Gaps = 23/205 (11%)

Query: 2944 KIEWYFNGKVLEQGSRFKLT---SDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            +++W+   ++++   RF +    +D G   L + DV   D G+Y C A+N+ GE+     
Sbjct: 135  EVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGES----- 189

Query: 3001 VYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDI 3060
               + K NL+ + +     + L++++   +S ++          G  PE     K+ V++
Sbjct: 190  ---SCKANLLLKEEEIVAPQVLDEVEAAPESSKQR---------GFAPEILQPLKE-VNV 236

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
             E   A ++  +  T   +  +EW  +G  +    RI   Y   +  L I   + TD G+
Sbjct: 237  PENDTAIFKCRV--TASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGS 294

Query: 3121 YSCRATNKWGQAEISVKLECVDKSK 3145
            Y C A N +G    S KL  V  SK
Sbjct: 295  YKCVARNNFGDISTSAKLRVVVNSK 319



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 60/233 (25%), Positives = 101/233 (43%), Gaps = 24/233 (10%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSI---FRFGY 693
           P+F   L+ V    G +  F+ R+    +    ++W K  + I+ + RF  I      G 
Sbjct: 107 PRFEERLRDVRVEIGREASFKVRVSLPAE----VDWFKGEEMIDDTGRFMIIDDDADKGL 162

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753
             L +  +  +D G Y C A +  G +  KA L +     +      P+ L  ++   + 
Sbjct: 163 FQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLKEEEIVA-----PQVLDEVEAAPES 217

Query: 754 SKYQHQESIEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPI 813
           SK         Q    P+ ++PL+++  + E   A F+ ++T    PT  VEW +DG  +
Sbjct: 218 SK---------QRGFAPEILQPLKEVN-VPENDTAIFKCRVTASPAPT--VEWLRDGVRV 265

Query: 814 TASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARS 866
           T   RI + +     +L I   R  D GSY   A N  G+  ++A +RV   S
Sbjct: 266 TEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNS 318



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 52/194 (26%), Positives = 74/194 (38%), Gaps = 6/194 (3%)

Query: 388 KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447
           K  AP         +  EG       R TG P P V WF +   ++ +       +ES +
Sbjct: 5   KGEAPVITSKLTRVECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDES-S 63

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
             L+I    ++D G   CV RN+ G       + V E+E+   P+F ER   + V  G  
Sbjct: 64  CTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNEREKGEGPRFEERLRDVRVEIGRE 123

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRI---HTDGGASTLDIPRAKASDAAWYQCT 564
                R V  P   + W K    I       I     D G   L I   +  D   Y+C 
Sbjct: 124 ASFKVR-VSLPA-EVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCV 181

Query: 565 AQNVAGSTATRARL 578
           A N  G ++ +A L
Sbjct: 182 AFNEVGESSCKANL 195



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 74/255 (29%), Positives = 112/255 (43%), Gaps = 40/255 (15%)

Query: 763  EEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSI 822
            E +  + P+F   L+D+  ++ GR A F+ +   VS P   V+W+K    I  + R   I
Sbjct: 100  EREKGEGPRFEERLRDV-RVEIGREASFKVR---VSLPA-EVDWFKGEEMIDDTGRFMII 154

Query: 823  ---FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTVTADLGIPEQRR 879
                + G   L+I  +R ED G Y   A N++GE+   A++ +     V      P+   
Sbjct: 155  DDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLKEEEIVA-----PQVLD 209

Query: 880  YIEKTXXXXXXXXXXXXXXXXXVPESTQK----PEFKTPIKDQISIKEGGFAHFEARLEP 935
             +E                    PES+++    PE   P+K+ +++ E   A F+ R+  
Sbjct: 210  EVE------------------AAPESSKQRGFAPEILQPLKE-VNVPENDTAIFKCRVTA 250

Query: 936  IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
                T  VEWL+DG  V    RI   +      LTI      D G Y C A N  G  +T
Sbjct: 251  SPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDIST 308

Query: 996  SANLTIV--TKKDII 1008
            SA L +V  +K DII
Sbjct: 309  SAKLRVVVNSKPDII 323



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 73/278 (26%), Positives = 121/278 (43%), Gaps = 24/278 (8%)

Query: 2316 SVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQR 2375
            ++K  N +   T   S T+  + +II++      + +  EL SA       + E    + 
Sbjct: 48   NLKPNNRVSAETDESSCTLIIQEAIINDEGSYRCVVR-NELGSALSTAEVLVNEREKGEG 106

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR---ITKTHDFG 2432
            P F + L+++  ++ G+ A F  R   V  P  +V+WF+ E++I+D+ R   I    D G
Sbjct: 107  PRFEERLRDV-RVEIGREASFKVR---VSLPA-EVDWFKGEEMIDDTGRFMIIDDDADKG 161

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQ 2492
               ++I  VR ED GVY C A N +GE               + E   P+ + +++   +
Sbjct: 162  LFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLK-----EEEIVAPQVLDEVEAAPE 216

Query: 2493 PHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELK 2552
              ++R   P  E  +P+  + +  P    E   A ++ RV     P+   EW  +GV + 
Sbjct: 217  SSKQRGFAP--EILQPL--KEVNVP----ENDTAIFKCRVT--ASPAPTVEWLRDGVRVT 266

Query: 2553 MGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
             G R    +     TL IN     D G Y C A N  G
Sbjct: 267  EGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFG 304



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 65/231 (28%), Positives = 100/231 (43%), Gaps = 31/231 (13%)

Query: 2235 EEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHIT 2294
            E  K   PRF   LR    V  G+ A F+ +V    +    ++++   + +    RF I 
Sbjct: 100  EREKGEGPRFEERLRDV-RVEIGREASFKVRVSLPAE----VDWFKGEEMIDDTGRFMII 154

Query: 2295 ---FDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLE 2351
                D G   L I    PED G Y   A N +G  +         K +++ + +     +
Sbjct: 155  DDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESS--------CKANLLLKEEEIVAPQ 206

Query: 2352 KIRELESAEPFKRPEIPEPVTRQR---PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTL 2408
             + E+E+A        PE  ++QR   P   QPL+ + N+ E  TA F CR+     PT 
Sbjct: 207  VLDEVEAA--------PES-SKQRGFAPEILQPLKEV-NVPENDTAIFKCRVTASPAPT- 255

Query: 2409 KVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             VEW R+   + +  RI   +     ++TI+  RD D G Y C A N  G+
Sbjct: 256  -VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGD 305



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 64/229 (27%), Positives = 93/229 (40%), Gaps = 22/229 (9%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTT---YDF 2032
            E P+F + +++  V  G     +     V+ P   V+W+     +    RF       D 
Sbjct: 105  EGPRFEERLRDVRVEIGREASFKVR---VSLPA-EVDWFKGEEMIDDTGRFMIIDDDADK 160

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092
            G   L I     ED G Y C A N VGE    SS K +         L E+ +   Q L+
Sbjct: 161  GLFQLSIDDVRPEDLGVYKCVAFNEVGE----SSCKANL-------LLKEEEIVAPQVLD 209

Query: 2093 KYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKI 2152
            + E   P   +Q G  P  L  L  + N+ E D A F+CRV     P  T++W  +G ++
Sbjct: 210  EVEAA-PESSKQRGFAPEILQPLKEV-NVPENDTAIFKCRVTA--SPAPTVEWLRDGVRV 265

Query: 2153 RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              G R    +      L I      D G+Y C A N  G+   +  L+V
Sbjct: 266  TEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRV 314



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 63/235 (26%), Positives = 102/235 (43%), Gaps = 24/235 (10%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF-- 1899
            + PRF  +L    ++  G+ A ++ R+   P     V+W+   +++    R+   +D   
Sbjct: 105  EGPRFEERLRD-VRVEIGREASFKVRVS-LP---AEVDWFKGEEMIDDTGRFMIIDDDAD 159

Query: 1900 -GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYL 1958
             G   L I  V  ED G Y C A N +G+  SS + N+  KE  I   Q    L++++  
Sbjct: 160  KGLFQLSIDDVRPEDLGVYKCVAFNEVGE--SSCKANLLLKEEEIVAPQ---VLDEVEAA 214

Query: 1959 EDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGR 2018
             + S+ +       F    P+  +P+K   V E      +  +T    PT  VEW  +G 
Sbjct: 215  PESSKQR------GFA---PEILQPLKEVNVPENDTAIFKCRVTASPAPT--VEWLRDGV 263

Query: 2019 PVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
             V +G R    Y      L I  A   D G+Y C A N  G+  T++ ++V   S
Sbjct: 264  RVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNS 318



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 57/233 (24%), Positives = 102/233 (43%), Gaps = 21/233 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT---T 322
           P+  ++ R+ +++ G +A F+V++S      V WFK  + + ++ +  II          
Sbjct: 107 PRFEERLRDVRVEIGREASFKVRVS--LPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQ 164

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
           L + + +  D G Y  +A N  G          ES  ++ +  +  + +      E E  
Sbjct: 165 LSIDDVRPEDLGVYKCVAFNEVG----------ESSCKANLLLKEEEIVAPQVLDEVEAA 214

Query: 383 IEIS-EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            E S ++  AP+ ++  ++ +V E     F CRVT  P P V W + D  +R     +I+
Sbjct: 215 PESSKQRGFAPEILQPLKEVNVPENDTAIFKCRVTASPAPTVEW-LRD-GVRVTEGRRIV 272

Query: 442 VNESGNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI--EKEQVVAP 491
                  A L I     +D G   CVARN  G+ +   +L V+   K  ++ P
Sbjct: 273 AQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSKPDIITP 325



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 3/100 (3%)

Query: 3413 EEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTF 3472
            +  KG+APV T  L+ +E + EG+ A    R T +  P   VEW+ +G +LK  +R    
Sbjct: 2    QRPKGEAPVITSKLTRVECV-EGDKATLSVRFTGSPTPT--VEWFKDGMNLKPNNRVSAE 58

Query: 3473 CDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
             D     L I      D G Y C   N  G A++TA + V
Sbjct: 59   TDESSCTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLV 98



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 17/173 (9%)

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQL 2621
            D G   L I+ V   D G+Y C A N  G                 ++ + P+  +++  
Sbjct: 159  DKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLKE-----EEIVAPQVLDEV-- 211

Query: 2622 KEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKN 2681
             EAA    PE     G   AP     LK  + + E      + +V     P   +EW ++
Sbjct: 212  -EAA----PESSKQRGF--APEILQPLKEVN-VPENDTAIFKCRVTASPAPT--VEWLRD 261

Query: 2682 GVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            GV +T G R+ + +   + TL+IN  R+ D G Y C A N  G+  ++A +++
Sbjct: 262  GVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRV 314



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +AP+ T+ L   +  VEG    L  +      P   +EWFK+G+ L    R+ +  D   
Sbjct: 7    EAPVITSKLTRVE-CVEGDKATLSVRFTGSPTPT--VEWFKDGMNLKPNNRVSAETDESS 63

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
             TL I     +D G Y C   N LG A+STA + + +R
Sbjct: 64   CTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 62/240 (25%), Positives = 98/240 (40%), Gaps = 26/240 (10%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            + P+F   L ++    G     + R+    +    V+WF   + I    RF    +    
Sbjct: 105  EGPRFEERLRDVRVEIGREASFKVRVSLPAE----VDWFKGEEMIDDTGRFMIIDDDADK 160

Query: 1369 ALDLLS---VYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLE 1425
             L  LS   V PED GVY C A N++GE+  SC   ++ K++ I+    P  L++++   
Sbjct: 161  GLFQLSIDDVRPEDLGVYKCVAFNEVGES--SCKANLLLKEEEIVA---PQVLDEVEAAP 215

Query: 1426 DTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQ 1485
            ++S+ +            P  +   K + NV E     F+C++         VEW ++G 
Sbjct: 216  ESSKQRG---------FAPEILQPLKEV-NVPENDTAIFKCRV--TASPAPTVEWLRDGV 263

Query: 1486 PVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSC--RLTCRSTTDIV 1543
             VT G R    +      L I      D G Y C A N  G    S   R+   S  DI+
Sbjct: 264  RVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRVVVNSKPDII 323



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            G+ PV  + LT +E + EGD+A    R      P  T++WF +G  ++  +R     D  
Sbjct: 6    GEAPVITSKLTRVECV-EGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDES 62

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               L I      D G+Y C   N+LG A++T  + V
Sbjct: 63   SCTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLV 98



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 49/204 (24%), Positives = 81/204 (39%), Gaps = 21/204 (10%)

Query: 1211 VEWFHNGRSVTVGSRFKTY---YDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267
            V+WF     +    RF       D G   L I      D G Y   A N +G +   A +
Sbjct: 136  VDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANL 195

Query: 1268 RVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTN 1327
             +++  +IV      Q +++++   +++++            AP+  + L  +   E   
Sbjct: 196  -LLKEEEIVAP----QVLDEVEAAPESSKQRGF---------APEILQPLKEVNVPENDT 241

Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQA 1387
               +CR+      T  VEW  +G  +  G R    Y  +   L +      D G Y C A
Sbjct: 242  AIFKCRVTASPAPT--VEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVA 299

Query: 1388 TNQLGEAVTSCALRVI--AKKDLI 1409
             N  G+  TS  LRV+  +K D+I
Sbjct: 300  RNNFGDISTSAKLRVVVNSKPDII 323



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 2/97 (2%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            +APV T  +  +   E   A    R    G P   VEW ++G+ ++ +NR++   D    
Sbjct: 7    EAPVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESSC 64

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
             L ++     D G+Y C   NELG A++++ + V  +
Sbjct: 65   TLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 52/199 (26%), Positives = 82/199 (41%), Gaps = 22/199 (11%)

Query: 4006 KVEWFFNGKPLLHKNRFTPI---YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAV 4062
            +V+WF   + +    RF  I    D G   ++   V PED G Y C A N  G    KA 
Sbjct: 135  EVDWFKGEEMIDDTGRFMIIDDDADKGLFQLSIDDVRPEDLGVYKCVAFNEVGESSCKAN 194

Query: 4063 IKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTV 4122
            +       ++ + ++     + + + E+EA+    PE    + +   P +   L + V V
Sbjct: 195  L-------LLKEEEIV----APQVLDEVEAA----PES--SKQRGFAPEILQPLKE-VNV 236

Query: 4123 EEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY-DGMYHFDIPKTRQYDTGKIE 4181
             E + A F CRVT  P P V WL +G  +  G R    Y D +    I + R  D G  +
Sbjct: 237  PENDTAIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYK 296

Query: 4182 VIXXXXXXXXXXXXXLKVI 4200
             +             L+V+
Sbjct: 297  CVARNNFGDISTSAKLRVV 315



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%)

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFV 1635
            +AP+ T+ L  VE  EG +A    R       T  VEW+ +   LK  +R +   +    
Sbjct: 7    EAPVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESSC 64

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
             L I   +  D G+Y C   N LG A+++   +V+ ++
Sbjct: 65   TLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNERE 102



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 2/85 (2%)

Query: 781 ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDA 840
           E  EG  A    + T    PT  VEW+KDG  +  ++R+++  +    +L I      D 
Sbjct: 19  ECVEGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDE 76

Query: 841 GSYTVRAVNKLGEAISTASIRVAAR 865
           GSY     N+LG A+STA + V  R
Sbjct: 77  GSYRCVVRNELGSALSTAEVLVNER 101



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 59/249 (23%), Positives = 97/249 (38%), Gaps = 38/249 (15%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVE-PKEDPKLRIEWYRNGKLLPSGHRYRTV---YDMG 3885
            P+F  +++   VE      F+ RV  P E     ++W++  +++    R+  +    D G
Sbjct: 107  PRFEERLRDVRVEIGREASFKVRVSLPAE-----VDWFKGEEMIDDTGRFMIIDDDADKG 161

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQ 3945
               L I  V  ED G Y C A N+ GE   KA +  K+  + I+  QV         L +
Sbjct: 162  LFQLSIDDVRPEDLGVYKCVAFNEVGESSCKANLLLKE--EEIVAPQV---------LDE 210

Query: 3946 MEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNM 4005
            +EA  +      +  E              + Q   + ++ E +T  F+C++     P  
Sbjct: 211  VEAAPESSKQRGFAPE--------------ILQPLKEVNVPENDTAIFKCRVT--ASPAP 254

Query: 4006 KVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK- 4064
             VEW  +G  +    R    Y      +        D G Y C A N +G   T A ++ 
Sbjct: 255  TVEWLRDGVRVTEGRRIVAQYLDEVATLTINQARDTDMGSYKCVARNNFGDISTSAKLRV 314

Query: 4065 -TTGKPGIV 4072
                KP I+
Sbjct: 315  VVNSKPDII 323



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 3/97 (3%)

Query: 65  RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
           RP   +P I  ++ +     +G  A    +  G+PTP V W +    L   N+ S   +E
Sbjct: 3   RPKGEAPVITSKLTR-VECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDE 61

Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            +   +L+I++    DEG Y C  RN+ G A+ +  +
Sbjct: 62  SS--CTLIIQEAIINDEGSYRCVVRNELGSALSTAEV 96



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 2/97 (2%)

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
            E P     +   E  EG    L    T    PT  VEW+ +G  ++  +R     D    
Sbjct: 7    EAPVITSKLTRVECVEGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDESSC 64

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             L I  A   D G+Y C   N +G A++T+ V V+ +
Sbjct: 65   TLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 2/94 (2%)

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
            +AP  +  L  +E VEG    L  R    G  T  VEWF +G  +K  +R     +    
Sbjct: 7    EAPVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESSC 64

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             L +      D G Y C   N+LG A+++  + V
Sbjct: 65   TLIIQEAIINDEGSYRCVVRNELGSALSTAEVLV 98



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 29/85 (34%), Positives = 36/85 (42%), Gaps = 3/85 (3%)

Query: 2506 EKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGF 2565
            E P+ T  LT   E  EG  A    R    G P+   EW+ +G+ LK  +R     D   
Sbjct: 7    EAPVITSKLTRV-ECVEGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDESS 63

Query: 2566 VTLDINSVVANDAGLYMCKAINRAG 2590
             TL I   + ND G Y C   N  G
Sbjct: 64   CTLIIQEAIINDEGSYRCVVRNELG 88



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/99 (26%), Positives = 47/99 (47%), Gaps = 6/99 (6%)

Query: 907  QKPEFKTPI----KDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            Q+P+ + P+      ++   EG  A    R    G  T  VEW KDG  ++ ++R++   
Sbjct: 2    QRPKGEAPVITSKLTRVECVEGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAET 59

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +     L I+   ++D G Y C   N +G A ++A + +
Sbjct: 60   DESSCTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLV 98



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            + PV T  L  ++ + EG  A    R    G PT  VEWF++   ++ ++R++   D   
Sbjct: 7    EAPVITSKLTRVECV-EGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESS 63

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
             ++ I      DEG Y C   N LG
Sbjct: 64   CTLIIQEAIINDEGSYRCVVRNELG 88



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P   Q  K     +   A F+ ++  +P P V W R    + E  +   +Y ++    +L
Sbjct: 225 PEILQPLKEVNVPENDTAIFKCRVTASPAPTVEWLRDGVRVTEGRRIVAQYLDEVA--TL 282

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            I Q    D G Y C ARN +G+   S  ++
Sbjct: 283 TINQARDTDMGSYKCVARNNFGDISTSAKLR 313



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 2/89 (2%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            V  S L  + C EGD          S  PT  +EWF +   L    R  +  D S  +L 
Sbjct: 10   VITSKLTRVECVEGDKATLSVRFTGSPTPT--VEWFKDGMNLKPNNRVSAETDESSCTLI 67

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            I      D G Y C   N  GSA ++  +
Sbjct: 68   IQEAIINDEGSYRCVVRNELGSALSTAEV 96



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 21/63 (33%), Positives = 29/63 (46%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G PT  ++WF +G      +RV    D     L I      D G Y C   N+ GSA +T
Sbjct: 34   GSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEGSYRCVVRNELGSALST 93

Query: 3783 AKI 3785
            A++
Sbjct: 94   AEV 96



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 34/96 (35%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            PV    L+    V EG    L  R    G PT  VEWF +G ++   +R     D     
Sbjct: 9    PVITSKLTRVECV-EGDKATLSVRFT--GSPTPTVEWFKDGMNLKPNNRVSAETDESSCT 65

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
            L I  A   D G Y     N LGSA ++A V V ER
Sbjct: 66   LIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 2/83 (2%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG  A    R    P P   VEW+ +G  L+  +R     D     L I      D G Y
Sbjct: 22   EGDKATLSVRFTGSPTPT--VEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEGSY 79

Query: 1918 TCKAINNLGQAVSSIRLNVQSKE 1940
             C   N LG A+S+  + V  +E
Sbjct: 80   RCVVRNELGSALSTAEVLVNERE 102



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 2/83 (2%)

Query: 1056 VEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGV 1115
            VEG  A    R       T TVEW+ +G  +   NR+    D     L I      D G 
Sbjct: 21   VEGDKATLSVRFTGSP--TPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEGS 78

Query: 1116 YTVVARNAAGEAQLSASMTVETR 1138
            Y  V RN  G A  +A + V  R
Sbjct: 79   YRCVVRNELGSALSTAEVLVNER 101



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P     L  V  +EG K     R    G PT  +EW K+G +++ ++R ++       +L
Sbjct: 9   PVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTL 66

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            +    I D G Y C   +  G A + A + V  R
Sbjct: 67  IIQEAIINDEGSYRCVVRNELGSALSTAEVLVNER 101



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 11/134 (8%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            + VEG    L   V     P   +EW+ +G  L+  +R    +D    TL + +    D 
Sbjct: 19   ECVEGDKATLS--VRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDE 76

Query: 2982 GIYTCKAYNKRGEAFTSSTVYCTSKD-----NLIERTQHPKGTEGLEKIQNLEDSLRKE- 3035
            G Y C   N+ G A +++ V    ++        ER +  +   G E    +  SL  E 
Sbjct: 77   GSYRCVVRNELGSALSTAEVLVNEREKGEGPRFEERLRDVRVEIGREASFKVRVSLPAEV 136

Query: 3036 ---PGQQPDDDTGR 3046
                G++  DDTGR
Sbjct: 137  DWFKGEEMIDDTGR 150



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE-QTGDVS 130
           P FE+  ++ R   G  A F  K+R +    V W + +  + +  ++ +  ++   G   
Sbjct: 107 PRFEERLRDVRVEIGREASF--KVRVSLPAEVDWFKGEEMIDDTGRFMIIDDDADKGLFQ 164

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAIC 157
           L I  + P D G Y C A N+ GE+ C
Sbjct: 165 LSIDDVRPEDLGVYKCVAFNEVGESSC 191



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 26/99 (26%), Positives = 36/99 (36%), Gaps = 2/99 (2%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G  P  T+  + +   E   A    R       +  VEWF +G  L   +RV    D   
Sbjct: 6    GEAPVITSKLTRVECVEGDKATLSVRF--TGSPTPTVEWFKDGMNLKPNNRVSAETDESS 63

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQ 3653
              L I      D G Y C   N  G A  + ++ V  R+
Sbjct: 64   CTLIIQEAIINDEGSYRCVVRNELGSALSTAEVLVNERE 102



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/79 (26%), Positives = 31/79 (39%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            VE  EG +    V     P   +EW+++G  L   +R     D    +L I      D G
Sbjct: 18   VECVEGDKATLSVRFTGSPTPTVEWFKDGMNLKPNNRVSAETDESSCTLIIQEAIINDEG 77

Query: 3901 EYICRAVNDFGEDFTKATI 3919
             Y C   N+ G   + A +
Sbjct: 78   SYRCVVRNELGSALSTAEV 96


>SB_54054| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 4232

 Score =  116 bits (279), Expect = 5e-25
 Identities = 102/396 (25%), Positives = 147/396 (37%), Gaps = 43/396 (10%)

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477
            QP  VF  +   F         P I W ++   I         T S  S L +  V   D
Sbjct: 601  QPKSVFTGDDVTFTCNATALAAPSIWWQKDGVNI---------TISDGSTLNLVNVKEGD 651

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            S  +  VAE    T    A  +  +         +PP  T    N      + V +    
Sbjct: 652  SGNYTCVAEAGENTTTSDAAFLSVK---------LPPVITNHPANQTANKDENVTIACSA 702

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
             GT+P +V WLKN +       +++ E     TL I    P D G Y+C   N       
Sbjct: 703  NGTEPFNVIWLKNNEVYDFSSDSRVHESHNNLTLEIFGVLPNDHGSYQCDVSNGR----- 757

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
                        DK  P T      P+ I   K K   EGQ ++F C+  G P P V W 
Sbjct: 758  -----------TDKSYPGTLIVKYAPQFIVEPKGKTTTEGQVVKFECQTTGNPSPNVTWL 806

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            K    +  S        +++  L I+     D G Y C A N  G ++  A L V    +
Sbjct: 807  KSGSAVNTS--VDPRFYSNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPE 864

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAV 4777
              N+P     +D    EG    F+        PT+ WL+ G+ +  + D +    G +  
Sbjct: 865  FVNVP-----QDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALNTSVDPRFYSNGTH-- 917

Query: 4778 LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            L+I N    D+G + C A++  G + T A L V  K
Sbjct: 918  LMITNVNRTDSGAYRCNASSILGVITTKASLDVYFK 953



 Score =  114 bits (274), Expect = 2e-24
 Identities = 109/405 (26%), Positives = 167/405 (41%), Gaps = 49/405 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            KP I T    P  V E E        +G P P  +W++++ P     + +     ++  L
Sbjct: 1137 KPDISTHP-SPQTVTEGENVTLSCAAEGRPTPSYQWFKDDSPFDAGNNARASL--SEGNL 1193

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCS-ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            I  +V  +D   +  +A N       S   L V             PS T   QN     
Sbjct: 1194 IFTKVSRDDHGQYYCLANNSVSNVTSSKVQLTV----------FFAPSITTHPQNQTKVE 1243

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G++V L   VTG     VYW ++G  +   +R  +   + + TL I     +D G Y C 
Sbjct: 1244 GEIVTLSCTVTGDPVPTVYWSRDGSNLTA-LRYLV---EPSNTLKIENLTREDEGSYICH 1299

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKI 4646
            A N+      DA  +                 N PP+ +E LK K    E   +  +CK+
Sbjct: 1300 AFNNVSSTSSDAAVLT---------------VNYPPKFLESLKPKETRNETDNLTLTCKL 1344

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTAD----EYTLRISEAFPEDEGDYKCVAYNSAG 4702
             GKP  TV W K +  +KP     +++ +     E TL I      DE  YKC A N+ G
Sbjct: 1345 EGKPQATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINLDRSDEASYKCRANNTVG 1404

Query: 4703 RVTVA-AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
             VT +   + V  P +   +P      +++  EG       Q+  K K ++ WL  G+L+
Sbjct: 1405 IVTSSNTTVTVQYPPKFFKIPD-----NVIKTEGSSVNLTCQLECKPKCSVTWLIGGSLL 1459

Query: 4762 PETPD----FQMIHEGNN-AVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              + D     Q  ++GN  + L+I N    D  ++TCRA  AAG+
Sbjct: 1460 DTSSDRISVTQPENDGNETSFLMISNLNRTDEASYTCRAKNAAGE 1504



 Score =  101 bits (242), Expect = 1e-20
 Identities = 108/423 (25%), Positives = 171/423 (40%), Gaps = 55/423 (13%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            +G +  + PP F + ++P     E +      + +G+PL  + W ++N  +K  PD    
Sbjct: 1951 QGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELK--PD---- 2004

Query: 4461 TFSTKSILIIRQVFVEDS--AVFAAVAENRGGTA--KCSANLVVEEKRRQGRGGIV---P 4513
                 S LII Q    DS  +    +  NR   A  KC AN  V+         +V   P
Sbjct: 2005 -----SRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYP 2059

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY---- 4569
            P F  + +N  VT    V L  ++       V WLK+   +        +   G+Y    
Sbjct: 2060 PKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTT 2119

Query: 4570 -TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
             +L I      D  +Y C AIN+AGE   +   +                 N PP+ +E 
Sbjct: 2120 SSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLT---------------VNYPPKFLES 2164

Query: 4629 LK-DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR----TADEYTLRIS 4683
            LK ++   E   +  +CK+ GKPL TV W K +  +KP     +++     + E TL+I 
Sbjct: 2165 LKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKII 2224

Query: 4684 EAFPEDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKT 4742
                 DE  YKC A N+     +    + V  P +    P     +D  V E        
Sbjct: 2225 NVNRHDEAYYKCRANNTVNTTASTNTSVVVQYPPKFFQSP-----KDKTVTEKSDVTLTC 2279

Query: 4743 QITSKIKPTIQWLREGALIPETP-DFQMIHEGN----NAVLLIGNTYEEDTGTFTCRATT 4797
            Q+  K K ++ WL++   +  +P    + H G+     + L I N    D   ++C+A  
Sbjct: 2280 QLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAIN 2339

Query: 4798 AAG 4800
            AAG
Sbjct: 2340 AAG 2342



 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 102/391 (26%), Positives = 150/391 (38%), Gaps = 45/391 (11%)

Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            E +  +FE +  G P P + W +    +  S D +   +S  +IL+I  V   DS  ++ 
Sbjct: 785  EGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVDPRF--YSNDTILMITNVSRIDSGTYSC 842

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543
             A N  G     A L V    R G      P F    Q+     G  V  +    G  P 
Sbjct: 843  NASNELGIISAEAALDV----RYG------PEFVNVPQDKTPNEGWSVTFECHTKGNPPP 892

Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
             V WLKNG  +   +  +    +GT+ L+I      DSG Y C A +  G     A   V
Sbjct: 893  TVTWLKNGSALNTSVDPRFYS-NGTH-LMITNVNRTDSGAYRCNASSILGVITTKASLDV 950

Query: 4604 SL-PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
               P     P PQT                 V EGQ +   C   G+P P+ QW+K D  
Sbjct: 951  YFKPDISTHPSPQT-----------------VTEGQNVTLLCVAEGRPTPSYQWFKDDSP 993

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA-AKLKVTQPDQADNL 4721
                   + S    E  L  ++   +D G Y C+A NS   VT + A+L V         
Sbjct: 994  FDAENNTRAS--LSEGNLIFTKISRDDHGQYYCLANNSVSNVTSSIAQLNVFFKPDISTY 1051

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ-MIHEGNNAVLLI 4780
            P+        + EG+          +  P+ QW ++ +      + +  + EGN   L+ 
Sbjct: 1052 PS-----PQTITEGENVTLLCVAEGRPSPSYQWFKDDSPFDAKYNTRASLSEGN---LIF 1103

Query: 4781 GNTYEEDTGTFTCRATTAAGQVETS-AKLVV 4810
                 +D G + C A  +   V +S AKL V
Sbjct: 1104 TKVSRDDHGQYYCLANNSVSNVTSSIAKLTV 1134



 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 57/188 (30%), Positives = 93/188 (49%), Gaps = 10/188 (5%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           APQF+   + +  TEG++ +F+C+ TG P P VTW  +   +    + +   N++    L
Sbjct: 771 APQFIVEPKGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVDPRFYSNDT---IL 827

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           MITNV+  DSG  +C A N+ G  + +  L+V        P+FV         EG  V  
Sbjct: 828 MITNVSRIDSGTYSCNASNELGIISAEAALDV-----RYGPEFVNVPQDKTPNEGWSVTF 882

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P P +TW K+G  +  + + R +++G  + L I     +D+  Y+C A ++ G
Sbjct: 883 ECHTKGNPPPTVTWLKNGSALNTSVDPRFYSNG--THLMITNVNRTDSGAYRCNASSILG 940

Query: 571 STATRARL 578
              T+A L
Sbjct: 941 VITTKASL 948



 Score = 96.7 bits (230), Expect = 4e-19
 Identities = 107/416 (25%), Positives = 166/416 (39%), Gaps = 55/416 (13%)

Query: 4410 PPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI------HTF 4462
            PP F + ++P     E +      + +G+P   + W ++N  +K  PD ++         
Sbjct: 1319 PPKFLESLKPKETRNETDNLTLTCKLEGKPQATVVWLKDNTELK--PDSRLIITQPSSVD 1376

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            S +S L I  +   D A +   A N  G    S   V  +          PP F     N
Sbjct: 1377 SGESTLTIINLDRSDEASYKCRANNTVGIVTSSNTTVTVQ---------YPPKFFKIPDN 1427

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDI-RNKIL--EEDGTYT--LLILEAY 4577
            V  T G  V L  ++       V WL  G  +     R  +   E DG  T  L+I    
Sbjct: 1428 VIKTEGSSVNLTCQLECKPKCSVTWLIGGSLLDTSSDRISVTQPENDGNETSFLMISNLN 1487

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK-IVAE 4636
              D   Y C A N+AGE    +   V+L            A N PP+ ++ LKD+  + E
Sbjct: 1488 RTDEASYTCRAKNAAGEKTSGS---VNL------------AVNYPPKFLQSLKDEETLNE 1532

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD----EYTLRISEAFPEDEGD 4692
               +  +CK+ GKPL TV W K +  ++P     +++ +     E TL I      DE  
Sbjct: 1533 TDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAY 1592

Query: 4693 YKCVAYNSAGRVTVAAKLKVT--QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            YKC+A N+    T      V    P +    P     ++  V E        Q+  K K 
Sbjct: 1593 YKCLANNTVDTTTSTTNTSVVVQYPPKFFQSP-----KNETVTEKSNVTLTCQLECKPKC 1647

Query: 4751 TIQWLREGALIPETPD-FQMIHEGN----NAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
            ++ WL++   +  +PD   + H G+     + L I N    D   ++C+A  AAG+
Sbjct: 1648 SVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGE 1703



 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 63/188 (33%), Positives = 79/188 (42%), Gaps = 11/188 (5%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+FV V QD+   EG    F+C   G P P VTW  N   +    + +   N  G H LM
Sbjct: 863  PEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALNTSVDPRFYSN--GTH-LM 919

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
            ITNV  +DSG   C A +  G    +  L+V  K     P      S   V EG+ V L 
Sbjct: 920  ITNVNRTDSGAYRCNASSILGVITTKASLDVYFK-----PDISTHPSPQTVTEGQNVTLL 974

Query: 512  ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN-VAG 570
              A G PTP   W KD  P       R     G   L   +    D   Y C A N V+ 
Sbjct: 975  CVAEGRPTPSYQWFKDDSPFDAENNTRASLSEG--NLIFTKISRDDHGQYYCLANNSVSN 1032

Query: 571  STATRARL 578
             T++ A+L
Sbjct: 1033 VTSSIAQL 1040



 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 95/407 (23%), Positives = 153/407 (37%), Gaps = 51/407 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            KP I T    P  V E +        +G P P  +W++++ P     D + +T ++ S  
Sbjct: 953  KPDISTHP-SPQTVTEGQNVTLLCVAEGRPTPSYQWFKDDSPF----DAENNTRASLS-- 1005

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQ--GRGGIVPPSFTLTAQNVNVT 4526
                   E + +F  ++ +  G   C AN  V               P  +       +T
Sbjct: 1006 -------EGNLIFTKISRDDHGQYYCLANNSVSNVTSSIAQLNVFFKPDISTYPSPQTIT 1058

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             G+ V L     G       W K+          +    +G   L+  +    D G+Y C
Sbjct: 1059 EGENVTLLCVAEGRPSPSYQWFKDDSPFDAKYNTRASLSEGN--LIFTKVSRDDHGQYYC 1116

Query: 4587 VAINSAGEARCD-AECVVSL-PATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
            +A NS        A+  V   P     P PQT                 V EG+ +  SC
Sbjct: 1117 LANNSVSNVTSSIAKLTVFFKPDISTHPSPQT-----------------VTEGENVTLSC 1159

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
               G+P P+ QW+K D         + S    E  L  ++   +D G Y C+A NS   V
Sbjct: 1160 AAEGRPTPSYQWFKDDSPFDAGNNARAS--LSEGNLIFTKVSRDDHGQYYCLANNSVSNV 1217

Query: 4705 TVAAKLKVTQPDQADNLPALT--PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
            T ++K+++T        P++T  P     V EG+       +T    PT+ W R+G+ + 
Sbjct: 1218 T-SSKVQLT----VFFAPSITTHPQNQTKV-EGEIVTLSCTVTGDPVPTVYWSRDGSNLT 1271

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809
                 + + E +N  L I N   ED G++ C A        + A ++
Sbjct: 1272 A---LRYLVEPSN-TLKIENLTREDEGSYICHAFNNVSSTSSDAAVL 1314



 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 103/432 (23%), Positives = 167/432 (38%), Gaps = 71/432 (16%)

Query: 4410 PPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQI------HTF 4462
            PP F + ++      E +      + +G+PL  + W ++N  ++  PD ++         
Sbjct: 1517 PPKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVWLKDNTELE--PDSRLIITQPSSVD 1574

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            S +S L I  V   D A +  +A N   T   + N  V  +         PP F  + +N
Sbjct: 1575 SGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQ--------YPPKFFQSPKN 1626

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY-----TLLILEAY 4577
              VT    V L  ++       V WLK+   +        +   G+Y     +L I    
Sbjct: 1627 ETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLV 1686

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
              D  +Y C AIN+AGE   +   +                 N PP+I+ P K+  + EG
Sbjct: 1687 RTDEARYSCKAINAAGEKTSEQGLLT---------------VNYPPKILTPPKNVTITEG 1731

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA----DEYTLRISEAFPEDEGDY 4693
              +  SC++ GKP  TV W  G   I+ S   + +  A        L I       EG Y
Sbjct: 1732 NDVTLSCEVEGKPEVTVDWLNGSTPIELSSVIEKTGLAVTGIGLSNLTIKGVSRYYEGSY 1791

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ---ITSKI-- 4748
            KC A                 PD +++ PA   +  +   + +  + +T    +T K+  
Sbjct: 1792 KCRAKR--------------DPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTCKLEG 1837

Query: 4749 KP--TIQWLREGALIPETPDFQMI------HEGNNAVLLIGNTYEEDTGTFTCRA-TTAA 4799
            KP  T+ WL++   +   PD ++I       E   + L I N    D   + CRA  T  
Sbjct: 1838 KPLATVVWLKDNTEL--KPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVN 1895

Query: 4800 GQVETSAKLVVK 4811
                T+  +VV+
Sbjct: 1896 TTASTNTSVVVQ 1907



 Score = 76.2 bits (179), Expect = 6e-13
 Identities = 67/254 (26%), Positives = 105/254 (41%), Gaps = 32/254 (12%)

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            T +L I      D  +Y C AIN+AGE   +   +                 N PP+ +E
Sbjct: 1920 TSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLT---------------VNYPPKFLE 1964

Query: 4628 PLK-DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD----EYTLRI 4682
             LK ++   E   +  +CK+ GKPL TV W K +  +KP     +++ +     E TL I
Sbjct: 1965 SLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTI 2024

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVT--QPDQADNLPALTPLRDIVVYEGQPAQF 4740
                  DE  YKC A N+    T      V    P +    P     ++  V E      
Sbjct: 2025 INVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYPPKFFQSP-----KNETVTEKSNVTL 2079

Query: 4741 KTQITSKIKPTIQWLREGALIPETPD-FQMIHEGN----NAVLLIGNTYEEDTGTFTCRA 4795
              Q+  K K ++ WL++   +  +PD   + H G+     + L I N    D   ++C+A
Sbjct: 2080 TCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKA 2139

Query: 4796 TTAAGQVETSAKLV 4809
              AAG+  +   L+
Sbjct: 2140 INAAGEKSSEQGLL 2153



 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 81/322 (25%), Positives = 126/322 (39%), Gaps = 45/322 (13%)

Query: 265  PPKIAQ--KPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
            PPK  +  KP  ++  E  +     +L G P   V W K+   L   ++           
Sbjct: 1959 PPKFLESLKPEETR-NETDNLTLTCKLEGKPLATVVWLKDNTELKPDSR----------- 2006

Query: 323  LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEER 382
            L +      DSG  TL   N N               E+Y +  R+    DT    T   
Sbjct: 2007 LIITQPSSVDSGESTLTIINVN------------RHDEAYYKC-RANNTVDTTTSTTNTS 2053

Query: 383  IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
            + +      P+F +  ++  VTE       C++  +P   VTW + D    D    +I V
Sbjct: 2054 VVVQ---YPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTW-LKDNTPLDTSPDRITV 2109

Query: 443  NESGNH-----ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF 497
               G++     +L ITN+  +D    +C A N +GE + +  L  +       PKF+E  
Sbjct: 2110 THPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN----YPPKFLESL 2165

Query: 498  STLNVR-EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH----TDGGASTLDIPR 552
                 R E + + L  +  G P   + W KD   + P+  L I      + G STL I  
Sbjct: 2166 KPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIIN 2225

Query: 553  AKASDAAWYQCTAQNVAGSTAT 574
                D A+Y+C A N   +TA+
Sbjct: 2226 VNRHDEAYYKCRANNTVNTTAS 2247



 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 60/196 (30%), Positives = 88/196 (44%), Gaps = 21/196 (10%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE---SGNH 448
            P+F K+  +   TEG      C++  +P   VTW I    + D  + +I V +    GN 
Sbjct: 1419 PKFFKIPDNVIKTEGSSVNLTCQLECKPKCSVTWLIGG-SLLDTSSDRISVTQPENDGNE 1477

Query: 449  A--LMITNVTLSDSGVVTCVARNKSGE-TAFQCRLNVIEKEQVVAPKFVERFS---TLNV 502
               LMI+N+  +D    TC A+N +GE T+    L V        PKF++      TLN 
Sbjct: 1478 TSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVN-----YPPKFLQSLKDEETLN- 1531

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI----HTDGGASTLDIPRAKASDA 558
             E + + L  +  G P   + W KD   + P+  L I      D G STL I      D 
Sbjct: 1532 -ETDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDE 1590

Query: 559  AWYQCTAQNVAGSTAT 574
            A+Y+C A N   +T +
Sbjct: 1591 AYYKCLANNTVDTTTS 1606



 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 101/425 (23%), Positives = 154/425 (36%), Gaps = 56/425 (13%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-----ST 4464
            PP F +  +   V E        + + +P   + W ++N P+  SPD    T      +T
Sbjct: 2059 PPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNT 2118

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQN 4522
             S L I  +   D A ++  A N  G       L+             PP F  +L  + 
Sbjct: 2119 TSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN---------YPPKFLESLKPEE 2169

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI----LEEDGTYTLLILEAYP 4578
                +  L  L  K+ G     V WLK+  +++PD R  I    L E G  TL I+    
Sbjct: 2170 TRNETDNLT-LTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNR 2228

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
             D   Y+C A N+          VV                  PP+  +  KDK V E  
Sbjct: 2229 HDEAYYKCRANNTVNTTASTNTSVV---------------VQYPPKFFQSPKDKTVTEKS 2273

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY-----TLRISEAFPEDEGDY 4693
             +  +C++  KP  +V W K +  +  S           +     +L I+     DE  Y
Sbjct: 2274 DVTLTCQLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARY 2333

Query: 4694 KCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK---IK 4749
             C A N+AG + +    L V  P +     A    R+    EGQ   F   +  K     
Sbjct: 2334 SCKAINAAGDKTSEQGLLTVNFPPRIFKTSA-NQTRE----EGQQITFTCDVEGKEGTSP 2388

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNN------AVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            P + W ++GA +    +        N      A L I N   ED G + C A  +   V 
Sbjct: 2389 PNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSLKTVY 2448

Query: 4804 TSAKL 4808
            ++  +
Sbjct: 2449 STPSI 2453



 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 57/178 (32%), Positives = 75/178 (42%), Gaps = 12/178 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            +TEG+     C   GRP P   WF +D      YN +  ++E GN  L+ T V+  D G 
Sbjct: 1057 ITEGENVTLLCVAEGRPSPSYQWFKDDSPFDAKYNTRASLSE-GN--LIFTKVSRDDHGQ 1113

Query: 463  VTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
              C+A N  S  T+   +L V  K     P      S   V EGE V L+  A G PTP 
Sbjct: 1114 YYCLANNSVSNVTSSIAKLTVFFK-----PDISTHPSPQTVTEGENVTLSCAAEGRPTPS 1168

Query: 522  ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN-VAGSTATRARL 578
              W KD  P       R     G   L   +    D   Y C A N V+  T+++ +L
Sbjct: 1169 YQWFKDDSPFDAGNNARASLSEG--NLIFTKVSRDDHGQYYCLANNSVSNVTSSKVQL 1224



 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 60/215 (27%), Positives = 87/215 (40%), Gaps = 18/215 (8%)

Query: 364  QDQRSQYI---TDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPY 420
            +D   QY     ++    T  +++++    AP      Q++   EG++    C VTG P 
Sbjct: 1200 RDDHGQYYCLANNSVSNVTSSKVQLTV-FFAPSITTHPQNQTKVEGEIVTLSCTVTGDPV 1258

Query: 421  PEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRL 480
            P V W    R   +    + LV  S  + L I N+T  D G   C A N    T+    +
Sbjct: 1259 PTVYW---SRDGSNLTALRYLVEPS--NTLKIENLTREDEGSYICHAFNNVSSTSSDAAV 1313

Query: 481  NVIEKEQVVAPKFVERFSTLNVR-EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539
              +       PKF+E       R E + + L  +  G P   + W KD   + P+  L I
Sbjct: 1314 LTVN----YPPKFLESLKPKETRNETDNLTLTCKLEGKPQATVVWLKDNTELKPDSRLII 1369

Query: 540  ----HTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  D G STL I     SD A Y+C A N  G
Sbjct: 1370 TQPSSVDSGESTLTIINLDRSDEASYKCRANNTVG 1404



 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 109/497 (21%), Positives = 183/497 (36%), Gaps = 56/497 (11%)

Query: 97   GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
            G+P P V W+R  + L      ++RY  +  + +L I+ +   DEG Y C A N      
Sbjct: 1255 GDPVPTVYWSRDGSNLT-----ALRYLVEPSN-TLKIENLTREDEGSYICHAFNNVSSTS 1308

Query: 157  CSVYIQPEGXXXXXXXXXXXXXYRHVSE--TVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
                +                  R+ ++  T+  K  G    T    +   ++   +   
Sbjct: 1309 SDAAVLTVNYPPKFLESLKPKETRNETDNLTLTCKLEGKPQATVVWLKDNTELKPDSRL- 1367

Query: 215  HSSTDDFKVDTFEYRL-LREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPR 273
               T    VD+ E  L +  +   +  + +    + V I T  + ++    PPK  + P 
Sbjct: 1368 -IITQPSSVDSGESTLTIINLDRSDEASYKCRANNTVGIVTSSNTTVTVQYPPKFFKIPD 1426

Query: 274  NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
            N    EG+      QL   P+  VTW   G  L  S+             R+  TQ  + 
Sbjct: 1427 NVIKTEGSSVNLTCQLECKPKCSVTWLIGGSLLDTSSD------------RISVTQPEND 1474

Query: 334  GHYT--LLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALA 391
            G+ T  L+  N N            +   SY    ++         +T   + ++     
Sbjct: 1475 GNETSFLMISNLN-----------RTDEASYTCRAKN-----AAGEKTSGSVNLAVN-YP 1517

Query: 392  PQFVKVCQDRD-VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN----ESG 446
            P+F++  +D + + E       C++ G+P   V W  ++ ++  D +  I+      +SG
Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVWLKDNTELEPD-SRLIITQPSSVDSG 1576

Query: 447  NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
               L I NV   D     C+A N    T      +V+ +     PKF +      V E  
Sbjct: 1577 ESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQ---YPPKFFQSPKNETVTEKS 1633

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA-----STLDIPRAKASDAAWY 561
             V L  +    P   +TW KD  P+  +P+    T  G+     S+L I     +D A Y
Sbjct: 1634 NVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARY 1693

Query: 562  QCTAQNVAGSTATRARL 578
             C A N AG   +   L
Sbjct: 1694 SCKAINAAGEKTSEQGL 1710



 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 77/337 (22%), Positives = 131/337 (38%), Gaps = 39/337 (11%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-----ST 4464
            PP F +  +   V E        + + +P   + W ++N P+  SPD    T      +T
Sbjct: 1617 PPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNT 1676

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
             S L I  +   D A ++  A N  G       L+             PP      +NV 
Sbjct: 1677 TSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVN---------YPPKILTPPKNVT 1727

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            +T G  V L  +V G   + V WL     ++    + ++E+ G    L +      +   
Sbjct: 1728 ITEGNDVTLSCEVEGKPEVTVDWLNGSTPIE---LSSVIEKTG----LAVTGIGLSNLTI 1780

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIVAEGQAIEFS 4643
            + V+    G  +C A+        +D    ++  A      +  LK ++   E   +  +
Sbjct: 1781 KGVSRYYEGSYKCRAK--------RDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLT 1832

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSR----TADEYTLRISEAFPEDEGDYKCVAYN 4699
            CK+ GKPL TV W K +  +KP     +++     + E TL+I      DE  YKC A N
Sbjct: 1833 CKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANN 1892

Query: 4700 SAG-----RVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
            +         +V  ++ VT P    N  +   + ++V
Sbjct: 1893 TVNTTASTNTSVVVQITVTHPGSYGNTTSSLTITNLV 1929



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 88/375 (23%), Positives = 143/375 (38%), Gaps = 50/375 (13%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVF-EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH 4460
            +G +  + PP F + ++P     E +      + +G+PL  + W ++N  +K  PD    
Sbjct: 2150 QGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELK--PD---- 2203

Query: 4461 TFSTKSILIIRQVFVEDS--AVFAAVAENRGGTA--KCSANLVVEEKRRQGRGGIV--PP 4514
                 S LII Q  + +S  +    +  NR   A  KC AN  V          +V  PP
Sbjct: 2204 -----SRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQYPP 2258

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY----- 4569
             F  + ++  VT    V L  ++       V WLK+   +        +   G++     
Sbjct: 2259 KFFQSPKDKTVTEKSDVTLTCQLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTS 2318

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ-TKAANAPPEIIEP 4628
            +L I      D  +Y C AIN+AG                DK   Q     N PP I + 
Sbjct: 2319 SLTITNLVRTDEARYSCKAINAAG----------------DKTSEQGLLTVNFPPRIFKT 2362

Query: 4629 LKDKIVAEGQAIEFSCKIVGK---PLPTVQWYKGDKLIKPSKYFQMSRTADEY------T 4679
              ++   EGQ I F+C + GK     P V W K    +        +++   Y      +
Sbjct: 2363 SANQTREEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTAS 2422

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739
            L I     EDEG Y+C A NS   V     + +T    +  +   +  +++   +     
Sbjct: 2423 LTIKNVQREDEGFYQCFAENSLKTVYSTPSIHLTVHFNS-TIFECSGAQNVTERQNDDVI 2481

Query: 4740 FKTQITSKIKPTIQW 4754
               ++  K KP + W
Sbjct: 2482 IWCEVEGKPKPEVSW 2496



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 56/178 (31%), Positives = 75/178 (42%), Gaps = 12/178 (6%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            VTEG+     C   GRP P   WF +D     + N +  ++E GN  L+ T ++  D G 
Sbjct: 965  VTEGQNVTLLCVAEGRPTPSYQWFKDDSPFDAENNTRASLSE-GN--LIFTKISRDDHGQ 1021

Query: 463  VTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
              C+A N  S  T+   +LNV  K     P      S   + EGE V L   A G P+P 
Sbjct: 1022 YYCLANNSVSNVTSSIAQLNVFFK-----PDISTYPSPQTITEGENVTLLCVAEGRPSPS 1076

Query: 522  ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN-VAGSTATRARL 578
              W KD  P       R     G   L   +    D   Y C A N V+  T++ A+L
Sbjct: 1077 YQWFKDDSPFDAKYNTRASLSEG--NLIFTKVSRDDHGQYYCLANNSVSNVTSSIAKL 1132



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 82/341 (24%), Positives = 130/341 (38%), Gaps = 39/341 (11%)

Query: 271  KPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI----ITTHNHTTLRVR 326
            KP  ++  E  +     +L G P   V W K+   L   ++  I    +     +TL++ 
Sbjct: 1818 KPEETR-NETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKII 1876

Query: 327  NTQKSDSGHYTLLAENP-NGCIVTSGYLAVESPTE---SYVQDQRSQYITDTQQRETEER 382
            N  + D  +Y   A N  N    T+  + V+       SY     S  IT+   R  E R
Sbjct: 1877 NVNRHDEAYYKCRANNTVNTTASTNTSVVVQITVTHPGSYGNTTSSLTITNLV-RTDEAR 1935

Query: 383  IEI----------SEKALA-----PQFVKVCQDRDV-TEGKMTRFDCRVTGRPYPEVTWF 426
                         SE+ L      P+F++  +  +   E       C++ G+P   V W 
Sbjct: 1936 YSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWL 1995

Query: 427  INDRQIRDDYNHKILVN----ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             ++ +++ D +  I+      +SG   L I NV   D     C A N    T      +V
Sbjct: 1996 KDNTELKPD-SRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTSV 2054

Query: 483  IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD 542
            + +     PKF +      V E   V L  +    P   +TW KD  P+  +P+    T 
Sbjct: 2055 VVQ---YPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTH 2111

Query: 543  GGA-----STLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             G+     S+L I     +D A Y C A N AG  ++   L
Sbjct: 2112 PGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGL 2152



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 72/302 (23%), Positives = 116/302 (38%), Gaps = 41/302 (13%)

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
            S L+I  +   D A +   A+N  G     S NL V            PP F  + ++  
Sbjct: 1479 SFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVN----------YPPKFLQSLKDEE 1528

Query: 4525 -VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE----EDGTYTLLILEAYPQ 4579
             +     + L  K+ G     V WLK+  +++PD R  I +    + G  TL I+  +  
Sbjct: 1529 TLNETDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRH 1588

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D   Y+C+A N+           V                  PP+  +  K++ V E   
Sbjct: 1589 DEAYYKCLANNTVDTTTSTTNTSV--------------VVQYPPKFFQSPKNETVTEKSN 1634

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY-----TLRISEAFPEDEGDYK 4694
            +  +C++  KP  +V W K +  +  S           Y     +L I+     DE  Y 
Sbjct: 1635 VTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYS 1694

Query: 4695 CVAYNSAGRVTVA-AKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
            C A N+AG  T     L V  P +      LTP +++ + EG       ++  K + T+ 
Sbjct: 1695 CKAINAAGEKTSEQGLLTVNYPPKI-----LTPPKNVTITEGNDVTLSCEVEGKPEVTVD 1749

Query: 4754 WL 4755
            WL
Sbjct: 1750 WL 1751



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 75/344 (21%), Positives = 129/344 (37%), Gaps = 45/344 (13%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHE----IITTHNH 320
            PPKI   P+N  + EG D     ++ G P   V W      +  S+  E     +T    
Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCEVEGKPEVTVDWLNGSTPIELSSVIEKTGLAVTGIGL 1775

Query: 321  TTLRVRNTQKSDSGHYTLLAE-NPNGCIVTSGYLAVESPTESYVQDQRSQ---------- 369
            + L ++   +   G Y   A+ +P+       Y+ V        ++ R++          
Sbjct: 1776 SNLTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTCKL 1835

Query: 370  ---------YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPY 420
                     ++ D  + + + R+ I++ +L        +  +V       + CR      
Sbjct: 1836 EGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNT-- 1893

Query: 421  PEVTWFINDRQIRDDYNHKILVNESGNH-----ALMITNVTLSDSGVVTCVARNKSGETA 475
               T   N   +      +I V   G++     +L ITN+  +D    +C A N +GE +
Sbjct: 1894 VNTTASTNTSVV-----VQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKS 1948

Query: 476  FQCRLNVIEKEQVVAPKFVERFSTLNVR-EGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534
             +  L  +       PKF+E       R E + + L  +  G P   + W KD   + P+
Sbjct: 1949 SEQGLLTVN----YPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPD 2004

Query: 535  PELRI----HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
              L I      D G STL I      D A+Y+C A N   +T +
Sbjct: 2005 SRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANNTVDTTTS 2048



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 98/406 (24%), Positives = 156/406 (38%), Gaps = 58/406 (14%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I T      +V E E         G+P+P + W R+   +  +  + +   +T   L 
Sbjct: 1230 PSITTHPQNQTKV-EGEIVTLSCTVTGDPVPTVYWSRDGSNL-TALRYLVEPSNT---LK 1284

Query: 4470 IRQVFVEDSAVFAAVAENR-GGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNVT 4526
            I  +  ED   +   A N    T+  +A L V            PP F  +L  +     
Sbjct: 1285 IENLTREDEGSYICHAFNNVSSTSSDAAVLTVN----------YPPKFLESLKPKETRNE 1334

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE----EDGTYTLLILEAYPQDSG 4582
            +  L  L  K+ G     V WLK+  +++PD R  I +    + G  TL I+     D  
Sbjct: 1335 TDNLT-LTCKLEGKPQATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINLDRSDEA 1393

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y+C A N+ G        +V+   T       T     PP+  +   + I  EG ++  
Sbjct: 1394 SYKCRANNTVG--------IVTSSNT-------TVTVQYPPKFFKIPDNVIKTEGSSVNL 1438

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPS----KYFQMSRTADEYT-LRISEAFPEDEGDYKCVA 4697
            +C++  KP  +V W  G  L+  S       Q     +E + L IS     DE  Y C A
Sbjct: 1439 TCQLECKPKCSVTWLIGGSLLDTSSDRISVTQPENDGNETSFLMISNLNRTDEASYTCRA 1498

Query: 4698 YNSAGRVTV-AAKLKVTQPDQADNLPALTPLRD-IVVYEGQPAQFKTQITSKIKPTIQWL 4755
             N+AG  T  +  L V  P +      L  L+D   + E        ++  K   T+ WL
Sbjct: 1499 KNAAGEKTSGSVNLAVNYPPK-----FLQSLKDEETLNETDNLTLTCKLEGKPLATVVWL 1553

Query: 4756 REGALIPETPDFQMI------HEGNNAVLLIGNTYEEDTGTFTCRA 4795
            ++   +   PD ++I       +   + L I N +  D   + C A
Sbjct: 1554 KDNTEL--EPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYKCLA 1597



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 52/196 (26%), Positives = 77/196 (39%), Gaps = 13/196 (6%)

Query: 392  PQFVKVCQDRDV-TEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL---VNESGN 447
            P+F++  +  +   E       C++ G+P   V W  ++ +++ D    I    + ESG 
Sbjct: 2159 PKFLESLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGE 2218

Query: 448  HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
              L I NV   D     C A N    TA      V++      PKF +      V E   
Sbjct: 2219 STLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQ----YPPKFFQSPKDKTVTEKSD 2274

Query: 508  VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA-----STLDIPRAKASDAAWYQ 562
            V L  +    P   +TW KD  P+  +P     T  G+     S+L I     +D A Y 
Sbjct: 2275 VTLTCQLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYS 2334

Query: 563  CTAQNVAGSTATRARL 578
            C A N AG   +   L
Sbjct: 2335 CKAINAAGDKTSEQGL 2350



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 52/184 (28%), Positives = 78/184 (42%), Gaps = 14/184 (7%)

Query: 3061 SEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGT 3120
            +EGQ+  +E     TG+ S  + W  +G  +  S   R  +     +L I      DSGT
Sbjct: 784  TEGQVVKFECQT--TGNPSPNVTWLKSGSAVNTSVDPR--FYSNDTILMITNVSRIDSGT 839

Query: 3121 YSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPD 3180
            YSC A+N+ G       L   D   G  P F    Q+ +   +G S  FEC      +P 
Sbjct: 840  YSCNASNELGIISAEAAL---DVRYG--PEFVNVPQD-KTPNEGWSVTFECHTK--GNPP 891

Query: 3181 MKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATIN 3240
              + W  NG  +  S   +  S+   ++  I      DSG Y C A +  G   T+A+++
Sbjct: 892  PTVTWLKNGSALNTSVDPRFYSNGTHLM--ITNVNRTDSGAYRCNASSILGVITTKASLD 949

Query: 3241 CYGK 3244
             Y K
Sbjct: 950  VYFK 953



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 77/360 (21%), Positives = 133/360 (36%), Gaps = 35/360 (9%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+ +   ++  +TEG      C V G+P   V W      I        ++ ++G   L 
Sbjct: 1717 PKILTPPKNVTITEGNDVTLSCEVEGKPEVTVDWLNGSTPIE----LSSVIEKTG---LA 1769

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQCRL----NVIEKEQV-VAPKFVERFSTLNVR-EG 505
            +T + LS+   +T    ++  E +++CR     +  E +   +   F+        R E 
Sbjct: 1770 VTGIGLSN---LTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRNET 1826

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH----TDGGASTLDIPRAKASDAAWY 561
            + + L  +  G P   + W KD   + P+  L I      + G STL I      D A+Y
Sbjct: 1827 DNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYY 1886

Query: 562  QCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXY-LRHVER 620
            +C A N   +TA+                   +    + +            Y  + +  
Sbjct: 1887 KCRANNTVNTTAS---TNTSVVVQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINA 1943

Query: 621  ARPYIPPGEEDRVYPPPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSI 679
            A           V  PP+F+  LK   T  E   +    ++E  G P   + WLK+   +
Sbjct: 1944 AGEKSSEQGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTEL 2001

Query: 680  EASSRF----TSIFRFGYISLDMLSLNIQDSGEYTCRA----VSATGVAETKAVLHVTPR 731
            +  SR      S    G  +L ++++N  D   Y CRA     + T    T  V+   P+
Sbjct: 2002 KPDSRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYPPK 2061



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 76/326 (23%), Positives = 125/326 (38%), Gaps = 24/326 (7%)

Query: 699  LSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQH 758
            LS  ++   E T   ++ +   E  +V+  T  A +        T++ + +  + S Y+ 
Sbjct: 1736 LSCEVEGKPEVTVDWLNGSTPIELSSVIEKTGLA-VTGIGLSNLTIKGVSRYYEGS-YKC 1793

Query: 759  QESIEEQTSQRPQFIRPLQDLGEL--QEGRNAHFEAQLTPVSD--PTMRVEWYKDGRPIT 814
            +   +  TS+       +  LG L  +E RN      LT   +  P   V W KD   + 
Sbjct: 1794 RAKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELK 1853

Query: 815  ASSRIT----SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST-ASIRVAARST-- 867
              SR+     S+   G  +L I+++   D   Y  RA N +    ST  S+ V    T  
Sbjct: 1854 PDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQITVTHP 1913

Query: 868  -----VTADLGIPEQRRYIEKTXXXXXXXXXXXXXXXXXVPESTQKPEFKTPIKDQISIK 922
                  T+ L I    R  E                   +      P+F   +K + +  
Sbjct: 1914 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEETRN 1973

Query: 923  EGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT----TFFNFGYVALTIKSVTVHD 978
            E        +LE  G     V WLKD   ++  SR+     +  + G   LTI +V  HD
Sbjct: 1974 ETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINVNRHD 2031

Query: 979  AGHYTCRAYNAIGQATTSANLTIVTK 1004
              +Y CRA N +   T++ N ++V +
Sbjct: 2032 EAYYKCRANNTVDTTTSTTNTSVVVQ 2057



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+   +P+     EG   +F+ Q +GNP P VTW K+G  +  S      +  N T L +
Sbjct: 772 PQFIVEPKGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVDPRFYS--NDTILMI 829

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            N  + DSG Y+  A N  G I     L V
Sbjct: 830 TNVSRIDSGTYSCNASNELGIISAEAALDV 859



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 2/90 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+    P++    EG    F+    GNP P VTW KNG  L  S      +  N T L +
Sbjct: 863 PEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALNTSVDPRFYS--NGTHLMI 920

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            N  ++DSG Y   A +  G I T   L V
Sbjct: 921 TNVNRTDSGAYRCNASSILGVITTKASLDV 950



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 47/190 (24%), Positives = 77/190 (40%), Gaps = 19/190 (10%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH--- 448
            P+F +  +D+ VTE       C++  +P   VTW + D    D    +I V   G+    
Sbjct: 2258 PKFFQSPKDKTVTEKSDVTLTCQLECKPKCSVTW-LKDNTPLDTSPVRITVTHPGSFGNT 2316

Query: 449  --ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
              +L ITN+  +D    +C A N +G+   +  L  +       P+  +  +     EG+
Sbjct: 2317 TSSLTITNLVRTDEARYSCKAINAAGDKTSEQGLLTVN----FPPRIFKTSANQTREEGQ 2372

Query: 507  PVVLNARAVG---TPTPRITWQKDGVPIIPNPELRIHTDG----GAST--LDIPRAKASD 557
             +       G   T  P + W+KDG  +  +             G ST  L I   +  D
Sbjct: 2373 QITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQRED 2432

Query: 558  AAWYQCTAQN 567
              +YQC A+N
Sbjct: 2433 EGFYQCFAEN 2442



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 80/359 (22%), Positives = 140/359 (38%), Gaps = 40/359 (11%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP+  T P ++ ++E +     C +       + V+W +   P+   S    I   G  +
Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCEV--EGKPEVTVDWLNGSTPIELSS---VIEKTGLAV 1770

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
              IG          T K  +R+ E +  C+ +   R     E   P++         K E
Sbjct: 1771 TGIG------LSNLTIKGVSRYYEGSYKCRAK---RDPDTSESD-PAYITVNFLGSLKPE 1820

Query: 3677 ETLHKREEITIEDEKPNPPRFTVE-IKDNIDV-PEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
            ET ++ + +T+  +    P  TV  +KDN ++ P+   +     +   G+ T++I   + 
Sbjct: 1821 ETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKI--INV 1878

Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
             R      +    N     A     +      + T      +G+ T++  IT   + D  
Sbjct: 1879 NRHDEAYYKCRANNTVNTTASTNTSVVV----QITVTHPGSYGNTTSSLTITNLVRTDEA 1934

Query: 3795 LESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIK-SHTVEESEGVRFECRV 3853
              S      +GEK  E  +G ++        V+ PPKF+  +K   T  E++ +   C++
Sbjct: 1935 RYSCKAINAAGEKSSE--QGLLT--------VNYPPKFLESLKPEETRNETDNLTLTCKL 1984

Query: 3854 EPKEDPKLRIEWYR-NGKLLPSGHRYRTV---YDMGFVSLDILYVYAEDSGEYICRAVN 3908
            E K  P   + W + N +L P      T     D G  +L I+ V   D   Y CRA N
Sbjct: 1985 EGK--PLATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINVNRHDEAYYKCRANN 2041



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 90/413 (21%), Positives = 143/413 (34%), Gaps = 47/413 (11%)

Query: 4368 TQKEVVGDKEITRKITSTET-TEIEHKAQTQERV-----VEGPVKPSKPPIFTKKMQPCR 4421
            TQ  +V   E T KI +     E  +K +    V         V    PP F +  +   
Sbjct: 2209 TQPSLVESGESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQYPPKFFQSPKDKT 2268

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF-----STKSILIIRQVFVE 4476
            V E        + + +P   + W ++N P+  SP     T      +T S L I  +   
Sbjct: 2269 VTEKSDVTLTCQLECKPKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRT 2328

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTK 4536
            D A ++  A N  G       L+             PP    T+ N     GQ +     
Sbjct: 2329 DEARYSCKAINAAGDKTSEQGLLTVN---------FPPRIFKTSANQTREEGQQITFTCD 2379

Query: 4537 VTG---TKPIDVYWLKNGKKVQPDIRNKILEEDGTY------TLLILEAYPQDSGKYECV 4587
            V G   T P +VYW K+G  V  D      +    Y      +L I     +D G Y+C 
Sbjct: 2380 VEGKEGTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCF 2439

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A NS        + V S P+        T   N+        ++    +   +   C++ 
Sbjct: 2440 AENS-------LKTVYSTPSIH-----LTVHFNSTIFECSGAQNVTERQNDDVIIWCEVE 2487

Query: 4648 GKPLPTVQWY-KG-DKLIKPSKYFQMSRTADEYTLRISEAFPE-DEGDYKCVAYNSAGRV 4704
            GKP P V W+ +G  + ++P+    + + A+    ++     + + GD          R 
Sbjct: 2488 GKPKPEVSWHVRGRGQQVEPNARITIEQPANTSRQKVRLVIKQVERGDTGMYYIKIGARS 2547

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLRE 4757
                 L V  P +  NL       D  V  G+      +      PT  WL++
Sbjct: 2548 YEPRLLNVQYPAENINLKVSD---DGKVDVGKQISLVCEAGGNPIPTFSWLKD 2597



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 36/108 (33%), Positives = 51/108 (47%), Gaps = 5/108 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F+   +  T  EG  + FE   +  G+P   + WLKNG ++  S      F      L
Sbjct: 863 PEFVNVPQDKTPNEGWSVTFECHTK--GNPPPTVTWLKNGSALNTS--VDPRFYSNGTHL 918

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
            + ++N  DSG Y C A S  GV  TKA L V  +  I  T   P+T+
Sbjct: 919 MITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDIS-THPSPQTV 965



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 111/497 (22%), Positives = 174/497 (35%), Gaps = 56/497 (11%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL-VECNKYSMRYNEQTGDV 129
            PP F Q  KN    +  N     +L   P   V+W +   PL    ++ ++ +    G+ 
Sbjct: 2059 PPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNT 2118

Query: 130  --SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSE--T 185
              SL I  +   DE  Y+C A N  GE      +                  R+ ++  T
Sbjct: 2119 TSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEETRNETDNLT 2178

Query: 186  VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL-LREVSFRESITKRY 244
            +  K  G    T    +   ++   +      T    V++ E  L +  V+  +    + 
Sbjct: 2179 LTCKLEGKPLATVVWLKDNTELKPDSRL--IITQPSLVESGESTLKIINVNRHDEAYYKC 2236

Query: 245  VGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
               + V  +   + S+    PPK  Q P++  + E +D     QL   P+  VTW K+  
Sbjct: 2237 RANNTVNTTASTNTSVVVQYPPKFFQSPKDKTVTEKSDVTLTCQLECKPKCSVTWLKDNT 2296

Query: 305  RLINSNKHEIITTH----NHTT--LRVRNTQKSDSGHYTLLAENPNGCIVT-SGYLAVES 357
             L +++   I  TH     +TT  L + N  ++D   Y+  A N  G   +  G L V  
Sbjct: 2297 PL-DTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQGLLTVNF 2355

Query: 358  PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
            P            I  T   +T E           Q    C   DV EGK         G
Sbjct: 2356 PPR----------IFKTSANQTREE--------GQQITFTC---DV-EGK--------EG 2385

Query: 418  RPYPEVTWFINDRQIRDDYNHKIL---VNESG--NHALMITNVTLSDSGVVTCVARN--K 470
               P V W  +   +  D N        N  G    +L I NV   D G   C A N  K
Sbjct: 2386 TSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSLK 2445

Query: 471  SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530
            +  +     L V     +      +    +  R+ + V++     G P P ++W   G  
Sbjct: 2446 TVYSTPSIHLTVHFNSTIFECSGAQ---NVTERQNDDVIIWCEVEGKPKPEVSWHVRGRG 2502

Query: 531  IIPNPELRIHTDGGAST 547
                P  RI  +  A+T
Sbjct: 2503 QQVEPNARITIEQPANT 2519



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 11/108 (10%)

Query: 628 GEEDRVYP-------PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIE 680
           G  D+ YP        PQFIV  K  T  EG  + FE   +  G+P+  + WLK+G ++ 
Sbjct: 756 GRTDKSYPGTLIVKYAPQFIVEPKGKTTTEGQVVKFEC--QTTGNPSPNVTWLKSGSAVN 813

Query: 681 ASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            S      F      L + +++  DSG Y+C A +  G+   +A L V
Sbjct: 814 TS--VDPRFYSNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDV 859



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 70/301 (23%), Positives = 113/301 (37%), Gaps = 15/301 (4%)

Query: 71   PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL-VECNKYSMRYNEQTGDV 129
            PP F +I  N    +G +     +L   P   V+W    + L    ++ S+   E  G+ 
Sbjct: 1418 PPKFFKIPDNVIKTEGSSVNLTCQLECKPKCSVTWLIGGSLLDTSSDRISVTQPENDGNE 1477

Query: 130  S--LLIKQIGPGDEGEYTCTARNQYGEAIC-SVYIQPEGXXXXXXXXXXXXXYRHVSE-T 185
            +  L+I  +   DE  YTC A+N  GE    SV +                        T
Sbjct: 1478 TSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEETLNETDNLT 1537

Query: 186  VEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRL-LREVSFRESITKRY 244
            +  K  G    T    +   ++   +      T    VD+ E  L +  V   +    + 
Sbjct: 1538 LTCKLEGKPLATVVWLKDNTELEPDSRL--IITQPSSVDSGESTLTIINVHRHDEAYYKC 1595

Query: 245  VGESDVQISTEIDRSLGPVS-PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNG 303
            +  + V  +T    +   V  PPK  Q P+N  + E ++     QL   P+  VTW K+ 
Sbjct: 1596 LANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDN 1655

Query: 304  QRLINSNKHEIIT---THNHTT--LRVRNTQKSDSGHYTLLAENPNGCIVT-SGYLAVES 357
              L  S     +T   ++ +TT  L + N  ++D   Y+  A N  G   +  G L V  
Sbjct: 1656 TPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVNY 1715

Query: 358  P 358
            P
Sbjct: 1716 P 1716



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 38/115 (33%), Positives = 53/115 (46%), Gaps = 7/115 (6%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT-SND 1898
            V  AP+FI +  G T  +EGQ   +EC+    P PN  V W  +G  + +    R  SND
Sbjct: 768  VKYAPQFIVEPKGKTT-TEGQVVKFECQTTGNPSPN--VTWLKSGSAVNTSVDPRFYSND 824

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
                 L I  V   DSG Y+C A N LG   +   L+V+     +   Q ++  E
Sbjct: 825  ---TILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQDKTPNE 876



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 57/240 (23%), Positives = 97/240 (40%), Gaps = 25/240 (10%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLT----TMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P   V WL++   ++  +RL     ++ + G   L +  VN  D   Y CRA N +  
Sbjct: 1837 GKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVNT 1896

Query: 1794 -AVTSSTLFVQSKASLQLESQHESALQKIQQL--EDSSRYQRR----------EDVEVAV 1840
             A T++++ VQ   +      + ++   I  L   D +RY  +          E   + V
Sbjct: 1897 TASTNTSVVVQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTV 1956

Query: 1841 NQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR----YRTS 1896
            N  P+F+  L      +E  +    C++E    P   V W  +   L+   R      +S
Sbjct: 1957 NYPPKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSS 2014

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLN--VQSKESIIRDSQHESALEK 1954
             D G + L I+ V   D   Y C+A N +    S+   +  VQ      +  ++E+  EK
Sbjct: 2015 VDSGESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEK 2074



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 6/100 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT----TFFNF 964
            P+F   +KD+ ++ E        +LE  G     V WLKD   +E  SR+     +  + 
Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLIITQPSSVDS 1575

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            G   LTI +V  HD  +Y C A N +   T++ N ++V +
Sbjct: 1576 GESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQ 1615



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 10/156 (6%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G +   + W  N +  + S   R   +   + LEI G    D G+Y C  +N  G+ + S
Sbjct: 704  GTEPFNVIWLKNNEVYDFSSDSRVHESHNNLTLEIFGVLPNDHGSYQCDVSN--GRTDKS 761

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
                 + K     P+F    +  +   +GQ   FEC      +P   + W  +G  +  S
Sbjct: 762  YPGTLIVK---YAPQFIVEPKG-KTTTEGQVVKFECQT--TGNPSPNVTWLKSGSAVNTS 815

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               +  S+    +L I      DSG Y C A N+ G
Sbjct: 816  VDPRFYSN--DTILMITNVSRIDSGTYSCNASNELG 849



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 1296 RRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKT 1355
            R  K     + V  APQF        T EG  V  EC  Q  G+ +  V W  +G  + T
Sbjct: 757  RTDKSYPGTLIVKYAPQFIVEPKGKTTTEGQVVKFEC--QTTGNPSPNVTWLKSGSAVNT 814

Query: 1356 GHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                 P +  +   L + +V   DSG Y+C A+N+LG      AL V
Sbjct: 815  S--VDPRFYSNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDV 859



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 46/195 (23%), Positives = 74/195 (37%), Gaps = 15/195 (7%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++EG+  +   S    G  +   +WF +    +A +  R   + G ++   +     D G
Sbjct: 1149 VTEGE--NVTLSCAAEGRPTPSYQWFKDDSPFDAGNNARASLSEGNLIFTKVSRD--DHG 1204

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             Y C A N       S     V  +    P  TTH QN +   +G+     CTV    DP
Sbjct: 1205 QYYCLANNSVSNVTSSK----VQLTVFFAPSITTHPQN-QTKVEGEIVTLSCTVT--GDP 1257

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
               + W  +G  +     +   S+     L I      D G Y+C A+N      + A +
Sbjct: 1258 VPTVYWSRDGSNLTALRYLVEPSN----TLKIENLTREDEGSYICHAFNNVSSTSSDAAV 1313

Query: 3240 NCYGKGGVYLESLQP 3254
                    +LESL+P
Sbjct: 1314 LTVNYPPKFLESLKP 1328



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 7/115 (6%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV--- 3881
            +V  PPKF    K+ TV E   V   C++E K  PK  + W ++   L +     TV   
Sbjct: 2055 VVQYPPKFFQSPKNETVTEKSNVTLTCQLECK--PKCSVTWLKDNTPLDTSPDRITVTHP 2112

Query: 3882 --YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVP 3934
              Y     SL I  +   D   Y C+A+N  GE  ++  +     P   L++  P
Sbjct: 2113 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKP 2167



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 7/110 (6%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTV--- 3881
            +V  PPKF    K+ TV E   V   C++E K  PK  + W ++   L +     TV   
Sbjct: 1613 VVQYPPKFFQSPKNETVTEKSNVTLTCQLECK--PKCSVTWLKDNTPLDTSPDRITVTHP 1670

Query: 3882 --YDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIIL 3929
              Y     SL I  +   D   Y C+A+N  GE  ++  +     P  IL
Sbjct: 1671 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVNYPPKIL 1720



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 34/123 (27%), Positives = 51/123 (41%), Gaps = 12/123 (9%)

Query: 3810 ELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
            ++  GR   +     IV   P+FI + K  T  E + V+FEC+      P   + W    
Sbjct: 752  DVSNGRTDKSYPGTLIVKYAPQFIVEPKGKTTTEGQVVKFECQTTGNPSP--NVTW---- 805

Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAE----DSGEYICRAVNDFGEDFTKATISCKKLP 3925
              L SG    T  D  F S D + +       DSG Y C A N+ G    +A +  +  P
Sbjct: 806  --LKSGSAVNTSVDPRFYSNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGP 863

Query: 3926 DII 3928
            + +
Sbjct: 864  EFV 866



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 7/112 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V   P+F     +    EG +V  EC  +  G+    V W  NG  + T     P + 
Sbjct: 857  LDVRYGPEFVNVPQDKTPNEGWSVTFECHTK--GNPPPTVTWLKNGSALNTS--VDPRFY 912

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
             +   L + +V   DSG Y C A++ LG   T  +L V  K D+   S HPS
Sbjct: 913  SNGTHLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI---STHPS 961



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 80/353 (22%), Positives = 130/353 (36%), Gaps = 48/353 (13%)

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRF----KTYYDFGFVALDIIHATSA 1245
            +E  N+ L C+LE  G P   V W  +   +   SR      +  + G   L II+    
Sbjct: 1824 NETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRH 1881

Query: 1246 DTGEYTVRA---VNHLGSAHTSAIVRV-IERSDIVTDTQNEQAIEQIQLLEDAARRTKQV 1301
            D   Y  RA   VN   S +TS +V++ +       +T +   I  +        RT + 
Sbjct: 1882 DEAYYKCRANNTVNTTASTNTSVVVQITVTHPGSYGNTTSSLTITNLV-------RTDEA 1934

Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLEC-RLQPVGDQTMRVEWFCN--GKPIKTGHR 1358
            R     + A     +   + TV      LE  + +   ++T  +   C   GKP+ T   
Sbjct: 1935 RYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEETRNETDNLTLTCKLEGKPLATVVW 1994

Query: 1359 FRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGL 1418
             +          D   + P+   + T  ++   GE+  +          +I  ++H    
Sbjct: 1995 LK----------DNTELKPDSRLIITQPSSVDSGESTLT----------IINVNRHDEAY 2034

Query: 1419 EKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKV 1478
             K +          T      V   P+F   PK+ E V E  +V   C+LE        V
Sbjct: 2035 YKCRANNTVDTTTSTTNTSVVVQYPPKFFQSPKN-ETVTEKSNVTLTCQLE--CKPKCSV 2091

Query: 1479 EWFKNGQPV-TIGHRFRPIHDFGY----VALDIIDLIAEDSGIYTCRAVNLVG 1526
             W K+  P+ T   R    H   Y     +L I +L+  D   Y+C+A+N  G
Sbjct: 2092 TWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAG 2144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 7/125 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            +V  PPKF    K  TV E   V   C++E K  PK  + W ++   L +     TV   
Sbjct: 2253 VVQYPPKFFQSPKDKTVTEKSDVTLTCQLECK--PKCSVTWLKDNTPLDTSPVRITVTHP 2310

Query: 3885 GFV-----SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
            G       SL I  +   D   Y C+A+N  G+  ++  +     P  I +    +  + 
Sbjct: 2311 GSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQGLLTVNFPPRIFKTSANQTREE 2370

Query: 3940 SEALT 3944
             + +T
Sbjct: 2371 GQQIT 2375



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 4/98 (4%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            ++  AP F +  K     E Q   FE +    G+P   V WL++G  +  S  +      
Sbjct: 767  IVKYAPQFIVEPKGKTTTEGQVVKFECQT--TGNPSPNVTWLKSGSAVNTS--VDPRFYS 822

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
                L +  V+  DSGTY+C A NELG     + L V+
Sbjct: 823  NDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVR 860



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 38/112 (33%), Positives = 51/112 (45%), Gaps = 14/112 (12%)

Query: 903  PESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFF 962
            PE    P+ KTP        EG    FE   +  G+    V WLK+G  +  S     F+
Sbjct: 863  PEFVNVPQDKTP-------NEGWSVTFECHTK--GNPPPTVTWLKNGSALNTSVD-PRFY 912

Query: 963  NFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHP 1014
            + G   L I +V   D+G Y C A + +G  TT A+L +  K DI   S HP
Sbjct: 913  SNG-THLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI---STHP 960



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 56/272 (20%), Positives = 90/272 (33%), Gaps = 14/272 (5%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            K     +G   KFE +  GNP+P V+W +  + +      S+     + D  L+I  +  
Sbjct: 779  KGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAV----NTSVDPRFYSNDTILMITNVSR 834

Query: 139  GDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTT 198
             D G Y+C A N+ G       +                     S T E    G    T 
Sbjct: 835  IDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQDKTPNEGWSVTFECHTKGNPPPTV 894

Query: 199  EQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDR 258
               +    +       ++S D        + ++  V+  +S   R    S + + T    
Sbjct: 895  TWLKNGSAL-------NTSVDPRFYSNGTHLMITNVNRTDSGAYRCNASSILGVIT-TKA 946

Query: 259  SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
            SL     P I+  P    + EG +        G P P   WFK+       N      + 
Sbjct: 947  SLDVYFKPDISTHPSPQTVTEGQNVTLLCVAEGRPTPSYQWFKDDSPFDAENNTRASLSE 1006

Query: 319  NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
             +  L      + D G Y  LA N    + +S
Sbjct: 1007 GN--LIFTKISRDDHGQYYCLANNSVSNVTSS 1036



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+F+   +  T  E   V FEC    K +P   + W +NG  L +    R  Y  G   L
Sbjct: 863  PEFVNVPQDKTPNEGWSVTFECHT--KGNPPPTVTWLKNGSALNTSVDPR-FYSNG-THL 918

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
             I  V   DSG Y C A +  G   TKA++     PDI
Sbjct: 919  MITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 54/260 (20%), Positives = 91/260 (35%), Gaps = 18/260 (6%)

Query: 85   QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
            +G N        G P+P   W +  +P     KY+ R +   G+  L+  ++   D G+Y
Sbjct: 1059 EGENVTLLCVAEGRPSPSYQWFKDDSPFDA--KYNTRASLSEGN--LIFTKVSRDDHGQY 1114

Query: 145  TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVS-ETVEHKAYGTQGYTTEQSRQ 203
             C A N       S+                     H S +TV      T     E    
Sbjct: 1115 YCLANNSVSNVTSSI--------AKLTVFFKPDISTHPSPQTVTEGENVTLSCAAEGRPT 1166

Query: 204  TQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRY-VGESDVQISTEIDRSLGP 262
                 + + +   + ++ +    E  L+     R+   + Y +  + V   T     L  
Sbjct: 1167 PSYQWFKDDSPFDAGNNARASLSEGNLIFTKVSRDDHGQYYCLANNSVSNVTSSKVQLTV 1226

Query: 263  VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
               P I   P+N    EG        ++G+P P V W ++G  L  +    ++   N  T
Sbjct: 1227 FFAPSITTHPQNQTKVEGEIVTLSCTVTGDPVPTVYWSRDGSNL--TALRYLVEPSN--T 1282

Query: 323  LRVRNTQKSDSGHYTLLAEN 342
            L++ N  + D G Y   A N
Sbjct: 1283 LKIENLTREDEGSYICHAFN 1302



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 41/169 (24%), Positives = 58/169 (34%), Gaps = 14/169 (8%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
           Q + V  G    F C  T    P + W       +D  N  I    S    L + NV   
Sbjct: 601 QPKSVFTGDDVTFTCNATALAAPSIWWQ------KDGVNITI----SDGSTLNLVNVKEG 650

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           DSG  TCVA      T        ++    + P      +     + E V +   A GT 
Sbjct: 651 DSGNYTCVAEAGENTTTSDAAFLSVK----LPPVITNHPANQTANKDENVTIACSANGTE 706

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
              + W K+      + + R+H      TL+I     +D   YQC   N
Sbjct: 707 PFNVIWLKNNEVYDFSSDSRVHESHNNLTLEIFGVLPNDHGSYQCDVSN 755



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 5/110 (4%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            V   P+F+  PK  +   EGQ V FEC+       N  V W K+G  V       P    
Sbjct: 768  VKYAPQFIVEPKG-KTTTEGQVVKFECQTTGNPSPN--VTWLKSGSAVNTS--VDPRFYS 822

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE 1549
                L I ++   DSG Y+C A N +G       L  R   + V   Q++
Sbjct: 823  NDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQDK 872



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 41/142 (28%), Positives = 60/142 (42%), Gaps = 7/142 (4%)

Query: 2606 IIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQ 2665
            I  +  R +  +   L   +++ V    V   V  AP  TTH ++  K VEG+ V L   
Sbjct: 1194 IFTKVSRDDHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTK-VEGEIVTLSCT 1252

Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
            V    DP   + W ++G  LT    L    +    TL I +L  +D G Y C A N +  
Sbjct: 1253 VTG--DPVPTVYWSRDGSNLTALRYLVEPSN----TLKIENLTREDEGSYICHAFNNVSS 1306

Query: 2726 AVSTASIKIEDRHWLLGESLHP 2747
              S A++   +      ESL P
Sbjct: 1307 TSSDAAVLTVNYPPKFLESLKP 1328



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 56/237 (23%), Positives = 95/237 (40%), Gaps = 19/237 (8%)

Query: 636  PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF----TSIFRF 691
            PP+ + P K+VT  EG  +     +E  G P + ++WL     IE SS       ++   
Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCEVE--GKPEVTVDWLNGSTPIELSSVIEKTGLAVTGI 1773

Query: 692  GYISLDMLSLNIQDSGEYTCRAVSATGVAET-KAVLHVTPRATI--ERTSQHPETLQYIQ 748
            G  +L +  ++    G Y CRA      +E+  A + V    ++  E T    + L    
Sbjct: 1774 GLSNLTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTC 1833

Query: 749  QLED---YSKYQHQESIEEQTSQRPQFIRP-LQDLGELQ---EGRNAHFEAQLTPVSDPT 801
            +LE     +    +++ E +   R    +P L + GE        N H EA     ++ T
Sbjct: 1834 KLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNT 1893

Query: 802  MRVEWYKDGRPITASSRITSIFNFGYV--SLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
            +          +     +T   ++G    SL I +L   D   Y+ +A+N  GE  S
Sbjct: 1894 VNTT-ASTNTSVVVQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSS 1949



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 1/71 (1%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF 4167
            R  P FV++P   T  EG    F C   G+P P V WL NG+ + N S     Y    H 
Sbjct: 860  RYGPEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSAL-NTSVDPRFYSNGTHL 918

Query: 4168 DIPKTRQYDTG 4178
             I    + D+G
Sbjct: 919  MITNVNRTDSG 929



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 56/285 (19%), Positives = 97/285 (34%), Gaps = 25/285 (8%)

Query: 72   PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
            P F  + ++    +G +  FE   +GNP P V+W +  + L      S+     +    L
Sbjct: 863  PEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSAL----NTSVDPRFYSNGTHL 918

Query: 132  LIKQIGPGDEGEYTCTARNQYG----EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVE 187
            +I  +   D G Y C A +  G    +A   VY +P+                H S    
Sbjct: 919  MITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPD-------------ISTHPSPQTV 965

Query: 188  HKAYGTQGYTTEQSRQTQKVA-YTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRY-V 245
             +          + R T     + + +   + ++ +    E  L+     R+   + Y +
Sbjct: 966  TEGQNVTLLCVAEGRPTPSYQWFKDDSPFDAENNTRASLSEGNLIFTKISRDDHGQYYCL 1025

Query: 246  GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
              + V   T     L     P I+  P    + EG +        G P P   WFK+   
Sbjct: 1026 ANNSVSNVTSSIAQLNVFFKPDISTYPSPQTITEGENVTLLCVAEGRPSPSYQWFKDDSP 1085

Query: 306  LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
                 K+    + +   L      + D G Y  LA N    + +S
Sbjct: 1086 F--DAKYNTRASLSEGNLIFTKVSRDDHGQYYCLANNSVSNVTSS 1128



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 53/232 (22%), Positives = 87/232 (37%), Gaps = 41/232 (17%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+Q L +   ++E  N+ L C+LE  G P   V W  +   +   SR           
Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSR----------- 1564

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I   +S D+GE T+  +N     H  A  + +  + + T T                 
Sbjct: 1565 LIITQPSSVDSGESTLTIIN--VHRHDEAYYKCLANNTVDTTTST--------------- 1607

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
                    + V   P+F ++  N    E +NV L C+L+        V W  +  P+ T 
Sbjct: 1608 ----TNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLE--CKPKCSVTWLKDNTPLDTS 1661

Query: 1357 -HRFRPAYEFDY----VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
              R    +   Y     +L + ++   D   Y+C+A N  GE  +   L  +
Sbjct: 1662 PDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTV 1713



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 8/125 (6%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR--- 1892
            V +AVN  P+F+  L     L+E  +    C++E    P   V W  +   L+   R   
Sbjct: 1510 VNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLII 1567

Query: 1893 -YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLN--VQSKESIIRDSQHE 1949
               +S D G + L I+ V+  D   Y C A N +    S+   +  VQ      +  ++E
Sbjct: 1568 TQPSSVDSGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQYPPKFFQSPKNE 1627

Query: 1950 SALEK 1954
            +  EK
Sbjct: 1628 TVTEK 1632



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 6/84 (7%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH----DF 2431
            P F Q L++ + + E       C+L   G P   V W ++   +E  SR+  T     D 
Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKL--EGKPLATVVWLKDNTELEPDSRLIITQPSSVDS 1575

Query: 2432 GYVSMTISHVRDEDEGVYMCRASN 2455
            G  ++TI +V   DE  Y C A+N
Sbjct: 1576 GESTLTIINVHRHDEAYYKCLANN 1599



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 7/86 (8%)

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
            D  V  G+ I   C+  G P+PT  W K D+  +       S      TLR  + F    
Sbjct: 2569 DGKVDVGKQISLVCEAGGNPIPTFSWLKDDENFRIDIVATKSDDKRNMTLREVQRF--YG 2626

Query: 4691 GDYKCVAYNSAGR-----VTVAAKLK 4711
            GDY CVA N  G+     VTVA ++K
Sbjct: 2627 GDYTCVARNGIGQEQKKTVTVAVEVK 2652



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V+ AP F    K      EGQ V  E Q      PN  + W K+G  + T   +   F  
Sbjct: 768  VKYAPQFIVEPKG-KTTTEGQVVKFECQTTGNPSPN--VTWLKSGSAVNTS--VDPRFYS 822

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                L I ++   DSG Y+C A+N LG   + A++ +
Sbjct: 823  NDTILMITNVSRIDSGTYSCNASNELGIISAEAALDV 859



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 16/41 (39%), Positives = 24/41 (58%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F+  P   T  EG+  +F C+ TG+P P V WL +G+ +
Sbjct: 772  PQFIVEPKGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAV 812



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 12/102 (11%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG+N+   C  E    PT   +WF ++ P  +G   +++   S  +L  T    +D G Y
Sbjct: 1151 EGENVTLSCAAEGR--PTPSYQWFKDDSPFDAGNNARAS--LSEGNLIFTKVSRDDHGQY 1206

Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFD---TQHPQGKAGLE 2885
             C A NS  S  TS  ++ T    ++F    T HPQ +  +E
Sbjct: 1207 YCLANNSV-SNVTSSKVQLT----VFFAPSITTHPQNQTKVE 1243



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 47/157 (29%), Positives = 69/157 (43%), Gaps = 21/157 (13%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS-RVKTI---NDF 3612
            PP+F   P ++I +E SS +  C+L      S  V W   G  L T S R+      ND 
Sbjct: 1418 PPKFFKIPDNVIKTEGSSVNLTCQLECKPKCS--VTWLIGGSLLDTSSDRISVTQPENDG 1475

Query: 3613 GFV-ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES 3671
                 L I  + + D   YTC+A N  GE T            + L    P  F    +S
Sbjct: 1476 NETSFLMISNLNRTDEASYTCRAKNAAGEKTSG---------SVNLAVNYPPKF---LQS 1523

Query: 3672 IQKLEETLHKREEITIEDEKPNPPRFTVE-IKDNIDV 3707
            + K EETL++ + +T+  +    P  TV  +KDN ++
Sbjct: 1524 L-KDEETLNETDNLTLTCKLEGKPLATVVWLKDNTEL 1559



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 58/244 (23%), Positives = 91/244 (37%), Gaps = 41/244 (16%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++ L      +E  N+ L C+LE  G P   V W  +   +   SR           
Sbjct: 1960 PKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSR----------- 2006

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I   +S D+GE T+  +N   + H  A  +   R++   DT                 
Sbjct: 2007 LIITQPSSVDSGESTLTIINV--NRHDEAYYKC--RANNTVDTT---------------- 2046

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
             T      + V   P+F ++  N    E +NV L C+L+        V W  +  P+ T 
Sbjct: 2047 -TSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLE--CKPKCSVTWLKDNTPLDTS 2103

Query: 1357 -HRFRPAYEFDY----VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILE 1411
              R    +   Y     +L + ++   D   Y+C+A N  GE  +   L  +      LE
Sbjct: 2104 PDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLE 2163

Query: 1412 SQHP 1415
            S  P
Sbjct: 2164 SLKP 2167



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 10/101 (9%)

Query: 1433 TDIIDESVTIK--PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-TI 1489
            T   + SV ++  P+F   PK+ E V E  +V   C+LE        V W K+  P+ T 
Sbjct: 1605 TSTTNTSVVVQYPPKFFQSPKN-ETVTEKSNVTLTCQLE--CKPKCSVTWLKDNTPLDTS 1661

Query: 1490 GHRFRPIHDFGY----VALDIIDLIAEDSGIYTCRAVNLVG 1526
              R    H   Y     +L I +L+  D   Y+C+A+N  G
Sbjct: 1662 PDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAG 1702



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 53/199 (26%), Positives = 85/199 (42%), Gaps = 26/199 (13%)

Query: 3542 SGTVDTLTPEAESG----NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
            + TVDT T    +      PP+F  +P +  ++E S+    C+L      S  V W  + 
Sbjct: 2040 NNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCS--VTWLKDN 2097

Query: 3598 KPLLTGSRVKTINDFGFV-----ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             PL T     T+   G        L I  + + D   Y+CKA N  GE +          
Sbjct: 2098 TPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKS--------SE 2149

Query: 3653 QGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVE-IKDNIDV-PEG 3710
            QG +L    P  F    ES+ K EET ++ + +T+  +    P  TV  +KDN ++ P+ 
Sbjct: 2150 QG-LLTVNYPPKF---LESL-KPEETRNETDNLTLTCKLEGKPLATVVWLKDNTELKPDS 2204

Query: 3711 GPVHFDCRVEPVGDPTMRI 3729
              +     +   G+ T++I
Sbjct: 2205 RLIITQPSLVESGESTLKI 2223



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 13/121 (10%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-----LMITNVTLSDSGVVTCVA 467
            C V G+P PEV+W +  R  + + N +I + +  N +     L+I  V   D+G+     
Sbjct: 2484 CEVEGKPKPEVSWHVRGRGQQVEPNARITIEQPANTSRQKVRLVIKQVERGDTGMYYI-- 2541

Query: 468  RNKSGETAFQCR-LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
              K G  +++ R LNV    + +  K V     ++V  G+ + L   A G P P  +W K
Sbjct: 2542 --KIGARSYEPRLLNVQYPAENINLK-VSDDGKVDV--GKQISLVCEAGGNPIPTFSWLK 2596

Query: 527  D 527
            D
Sbjct: 2597 D 2597



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 5/102 (4%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P  ++EG++    C  E  P P+   +W+ +     +G+  R S   G   L    V  +
Sbjct: 1146 PQTVTEGENVTLSCAAEGRPTPSY--QWFKDDSPFDAGNNARASLSEG--NLIFTKVSRD 1201

Query: 1913 DSGEYTCKAINNLGQAVSS-IRLNVQSKESIIRDSQHESALE 1953
            D G+Y C A N++    SS ++L V    SI    Q+++ +E
Sbjct: 1202 DHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTKVE 1243



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 9/131 (6%)

Query: 1687 RLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEW 1746
            R N   DT+    +++   V+   P F    K+  V E        +L     PK  V W
Sbjct: 2038 RANNTVDTTTSTTNTSV--VVQYPPKFFQSPKNETVTEKSNVTLTCQL--ECKPKCSVTW 2093

Query: 1747 LRNGVPIEAS-NRLTTMH--DFGYVALNMKYVN--PEDSGTYTCRAINELGEAVTSSTLF 1801
            L++  P++ S +R+T  H   +G    ++   N    D   Y+C+AIN  GE  +   L 
Sbjct: 2094 LKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLL 2153

Query: 1802 VQSKASLQLES 1812
              +     LES
Sbjct: 2154 TVNYPPKFLES 2164



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 10/104 (9%)

Query: 636  PPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF----TSIFR 690
            PP+F+  LK   T  E   +    ++E  G P   + WLK+   ++  SR      S+  
Sbjct: 2158 PPKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSLVE 2215

Query: 691  FGYISLDMLSLNIQDSGEYTCRA---VSATGVAETKAVLHVTPR 731
             G  +L ++++N  D   Y CRA   V+ T    T  V+   P+
Sbjct: 2216 SGESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQYPPK 2259



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 7/100 (7%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT----TFFNF 964
            P+F   +K + +  E        +LE  G     V WLKD   ++  SR+     +    
Sbjct: 2159 PKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSLVES 2216

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            G   L I +V  HD  +Y CRA N +   T S N ++V +
Sbjct: 2217 GESTLKIINVNRHDEAYYKCRANNTV-NTTASTNTSVVVQ 2255



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 7/100 (7%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN-RLTTMH- 1763
            V+   P F    KD  V E        +L     PK  V WL++  P++ S  R+T  H 
Sbjct: 2253 VVQYPPKFFQSPKDKTVTEKSDVTLTCQL--ECKPKCSVTWLKDNTPLDTSPVRITVTHP 2310

Query: 1764 -DFGYVALNMKYVN--PEDSGTYTCRAINELGEAVTSSTL 1800
              FG    ++   N    D   Y+C+AIN  G+  +   L
Sbjct: 2311 GSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQGL 2350



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 7/91 (7%)

Query: 3826 VSTPPKFITQIK-SHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTV-- 3881
            V+ PPKF+  +K   T  E++ +   C++E K  P+  + W + N +L P      T   
Sbjct: 1316 VNYPPKFLESLKPKETRNETDNLTLTCKLEGK--PQATVVWLKDNTELKPDSRLIITQPS 1373

Query: 3882 -YDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
              D G  +L I+ +   D   Y CRA N  G
Sbjct: 1374 SVDSGESTLTIINLDRSDEASYKCRANNTVG 1404



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 8/126 (6%)

Query: 2339 SIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDC 2398
            +II+ ++  E   K R   + +          V +  P F Q  +N + + E       C
Sbjct: 2023 TIINVNRHDEAYYKCRANNTVDTTTSTTNTSVVVQYPPKFFQSPKN-ETVTEKSNVTLTC 2081

Query: 2399 RLIPVGDPTLKVEWFRNEKLIEDS-SRITKTHDFGY----VSMTISHVRDEDEGVYMCRA 2453
            +L     P   V W ++   ++ S  RIT TH   Y     S+TI+++   DE  Y C+A
Sbjct: 2082 QL--ECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKA 2139

Query: 2454 SNLLGE 2459
             N  GE
Sbjct: 2140 INAAGE 2145



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 5/77 (6%)

Query: 943  VEWLKDGRPVEAS-SRITTFFNFGY----VALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997
            V WLKD  P++ S  RIT      Y     +LTI ++   D   Y+C+A NA G+ ++  
Sbjct: 2091 VTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQ 2150

Query: 998  NLTIVTKKDIIAESQHP 1014
             L  V       ES  P
Sbjct: 2151 GLLTVNYPPKFLESLKP 2167



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K  P+F+ + + +T+  E +  KFECQ    G+P+  V W  +G  +       P +   
Sbjct: 769  KYAPQFIVEPKGKTT-TEGQVVKFECQTT--GNPSPNVTWLKSGSAV--NTSVDPRFYSN 823

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
               +    V   DSG Y C A+N  G+   +A +     P  V
Sbjct: 824  DTILMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFV 866



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%)

Query: 1185 NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244
            +P  V+EG+N+ L C  E  G PT   +WF +      G+  +     G   L     + 
Sbjct: 1145 SPQTVTEGENVTLSCAAE--GRPTPSYQWFKDDSPFDAGNNARASLSEG--NLIFTKVSR 1200

Query: 1245 ADTGEYTVRAVNHLGSAHTSAI-VRVIERSDIVTDTQNEQAIE 1286
             D G+Y   A N + +  +S + + V     I T  QN+  +E
Sbjct: 1201 DDHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTKVE 1243



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 7/100 (7%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS-NRLTTMH- 1763
            V+   P F    K+  V E        +L     PK  V WL++  P++ S +R+T  H 
Sbjct: 1613 VVQYPPKFFQSPKNETVTEKSNVTLTCQL--ECKPKCSVTWLKDNTPLDTSPDRITVTHP 1670

Query: 1764 -DFGYVALNMKYVN--PEDSGTYTCRAINELGEAVTSSTL 1800
              +G    ++   N    D   Y+C+AIN  GE  +   L
Sbjct: 1671 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGL 1710



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 5/65 (7%)

Query: 943  VEWLKDGRPVEAS-SRITTFFNFGY----VALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997
            V WLKD  P++ S  RIT      Y     +LTI ++   D   Y+C+A NA G+ T+  
Sbjct: 1649 VTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQ 1708

Query: 998  NLTIV 1002
             L  V
Sbjct: 1709 GLLTV 1713



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 5/105 (4%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            +D +  P FV   Q +T       T FEC     G+P   V W  NG  L       P +
Sbjct: 857  LDVRYGPEFVNVPQDKTPNEGWSVT-FECHTK--GNPPPTVTWLKNGSAL--NTSVDPRF 911

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
                  +    V   DSG Y C A+++ G+  TKA +    KP I
Sbjct: 912  YSNGTHLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 4/102 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            PEF   P D   +E  S  FEC      +    V W  NG  L T    +  ++   ++ 
Sbjct: 863  PEFVNVPQDKTPNEGWSVTFECHT--KGNPPPTVTWLKNGSALNTSVDPRFYSNGTHLM- 919

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
             I  V + D+G Y C A++  G  T    L V  +  I   P
Sbjct: 920  -ITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDISTHP 960



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 4/79 (5%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  V  E   +    P   + W KNG  L T   +   F      L I ++   DSG Y
Sbjct: 876  EGWSVTFECHTKGNPPPT--VTWLKNGSALNTS--VDPRFYSNGTHLMITNVNRTDSGAY 931

Query: 2716 TCKATNLLGEAVSTASIKI 2734
             C A+++LG   + AS+ +
Sbjct: 932  RCNASSILGVITTKASLDV 950



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 11/123 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I     TD   YSC+A N  G+      L  V+      P+  T  +N+  + +G   
Sbjct: 1680 LTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVN----YPPKILTPPKNVT-ITEGNDV 1734

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK----TVSDFGFVVLDIAYTQNHDSGEYV 3223
               C V     P++ ++W +   P+  S+ I+     V+  G   L I     +  G Y 
Sbjct: 1735 TLSCEV--EGKPEVTVDWLNGSTPIELSSVIEKTGLAVTGIGLSNLTIKGVSRYYEGSYK 1792

Query: 3224 CRA 3226
            CRA
Sbjct: 1793 CRA 1795



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 5/65 (7%)

Query: 943  VEWLKDGRPVEASS-RITTFF--NFGYV--ALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997
            V WLKD  P++ S  RIT     +FG    +LTI ++   D   Y+C+A NA G  T+  
Sbjct: 2289 VTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQ 2348

Query: 998  NLTIV 1002
             L  V
Sbjct: 2349 GLLTV 2353



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 4/103 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P+F   P     +E     FEC+     + S  V W  +G  + T    +  ++    IL
Sbjct: 772  PQFIVEPKGKTTTEGQVVKFECQT--TGNPSPNVTWLKSGSAVNTSVDPRFYSND--TIL 827

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
             I  V + D+G Y+C A+N  G  +    L V+     +  PQ
Sbjct: 828  MITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQ 870



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 32/103 (31%), Positives = 42/103 (40%), Gaps = 5/103 (4%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V   P F+      T  +EG S  +EC  +  P P   V W  NG  L +    R  ++ 
Sbjct: 859  VRYGPEFVNVPQDKTP-NEGWSVTFECHTKGNPPPT--VTWLKNGSALNTSVDPRFYSNG 915

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
                L I  V   DSG Y C A + LG   +   L+V  K  I
Sbjct: 916  --THLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 30/124 (24%), Positives = 49/124 (39%), Gaps = 5/124 (4%)

Query: 2606 IIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQ 2665
            I  +  R +  +   L   +++ V        V   P  +TH  S   + EG++V L   
Sbjct: 1102 IFTKVSRDDHGQYYCLANNSVSNVTSSIAKLTVFFKPDISTH-PSPQTVTEGENVTLSCA 1160

Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
             E R  P+   +WFK+      G   +++   G   L    +  DD G Y C A N +  
Sbjct: 1161 AEGRPTPSY--QWFKDDSPFDAGNNARASLSEG--NLIFTKVSRDDHGQYYCLANNSVSN 1216

Query: 2726 AVST 2729
              S+
Sbjct: 1217 VTSS 1220



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 54/222 (24%), Positives = 84/222 (37%), Gaps = 42/222 (18%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F++ L      +E  N+ L C+LE  G P   V W  +   +   SR           
Sbjct: 1320 PKFLESLKPKETRNETDNLTLTCKLE--GKPQATVVWLKDNTELKPDSR----------- 1366

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAAR 1296
            L I   +S D+GE T+  +N   S   S   R      IVT +                 
Sbjct: 1367 LIITQPSSVDSGESTLTIINLDRSDEASYKCRANNTVGIVTSSNTT-------------- 1412

Query: 1297 RTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG 1356
                    +TV   P+F +   N+   EG++V+L C+L+        V W   G  + T 
Sbjct: 1413 --------VTVQYPPKFFKIPDNVIKTEGSSVNLTCQLE--CKPKCSVTWLIGGSLLDTS 1462

Query: 1357 HR----FRPAYEFDYVALDLLS-VYPEDSGVYTCQATNQLGE 1393
                   +P  + +  +  ++S +   D   YTC+A N  GE
Sbjct: 1463 SDRISVTQPENDGNETSFLMISNLNRTDEASYTCRAKNAAGE 1504



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH----DF 2431
            P F + L+  +   E       C+L   G P   V W ++   ++  SR+  T     D 
Sbjct: 1320 PKFLESLKPKETRNETDNLTLTCKL--EGKPQATVVWLKDNTELKPDSRLIITQPSSVDS 1377

Query: 2432 GYVSMTISHVRDEDEGVYMCRASNLLG 2458
            G  ++TI ++   DE  Y CRA+N +G
Sbjct: 1378 GESTLTIINLDRSDEASYKCRANNTVG 1404



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 8/90 (8%)

Query: 634  YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFR--- 690
            YPP  F +P  +V   EG  ++   ++E    P   + WL  G  ++ SS   S+ +   
Sbjct: 1417 YPPKFFKIP-DNVIKTEGSSVNLTCQLEC--KPKCSVTWLIGGSLLDTSSDRISVTQPEN 1473

Query: 691  -FGYISLDMLS-LNIQDSGEYTCRAVSATG 718
                 S  M+S LN  D   YTCRA +A G
Sbjct: 1474 DGNETSFLMISNLNRTDEASYTCRAKNAAG 1503



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 16/138 (11%)

Query: 3776 WGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQ 3835
            +G+ T++  IT   + D    S      +GEK  E  +G ++        V+ PPK +T 
Sbjct: 1673 YGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSE--QGLLT--------VNYPPKILTP 1722

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP-SGHRYRT---VYDMGFVSLDI 3891
             K+ T+ E   V   C VE K  P++ ++W      +  S    +T   V  +G  +L I
Sbjct: 1723 PKNVTITEGNDVTLSCEVEGK--PEVTVDWLNGSTPIELSSVIEKTGLAVTGIGLSNLTI 1780

Query: 3892 LYVYAEDSGEYICRAVND 3909
              V     G Y CRA  D
Sbjct: 1781 KGVSRYYEGSYKCRAKRD 1798



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH----DF 2431
            P F + L+  +   E       C+L   G P   V W ++   ++  SR+  T     D 
Sbjct: 1960 PKFLESLKPEETRNETDNLTLTCKL--EGKPLATVVWLKDNTELKPDSRLIITQPSSVDS 2017

Query: 2432 GYVSMTISHVRDEDEGVYMCRASN 2455
            G  ++TI +V   DE  Y CRA+N
Sbjct: 2018 GESTLTIINVNRHDEAYYKCRANN 2041



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 3/79 (3%)

Query: 395  VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
            +KV  D  V  GK     C   G P P  +W  +D   R D    +         + +  
Sbjct: 2564 LKVSDDGKVDVGKQISLVCEAGGNPIPTFSWLKDDENFRIDI---VATKSDDKRNMTLRE 2620

Query: 455  VTLSDSGVVTCVARNKSGE 473
            V     G  TCVARN  G+
Sbjct: 2621 VQRFYGGDYTCVARNGIGQ 2639



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 6/72 (8%)

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS-ANLTIV 1002
            +W KD  P +A        + G +  T   V+  D G Y C A N++   T+S A LT+ 
Sbjct: 1078 QWFKDDSPFDAKYNTRASLSEGNLIFT--KVSRDDHGQYYCLANNSVSNVTSSIAKLTVF 1135

Query: 1003 TKKDIIAESQHP 1014
             K DI   S HP
Sbjct: 1136 FKPDI---STHP 1144



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 37/125 (29%), Positives = 55/125 (44%), Gaps = 11/125 (8%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-TIGHRFRPIH- 1497
            V   P+F   PK  + V E   V   C+LE        V W K+  P+ T   R    H 
Sbjct: 2254 VQYPPKFFQSPKD-KTVTEKSDVTLTCQLE--CKPKCSVTWLKDNTPLDTSPVRITVTHP 2310

Query: 1498 -DFGYV--ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCR--LTCRSTTDIVRSTQNEAGL 1552
              FG    +L I +L+  D   Y+C+A+N  G D+ S +  LT      I +++ N+   
Sbjct: 2311 GSFGNTTSSLTITNLVRTDEARYSCKAINAAG-DKTSEQGLLTVNFPPRIFKTSANQTRE 2369

Query: 1553 EQIQV 1557
            E  Q+
Sbjct: 2370 EGQQI 2374



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 44/160 (27%), Positives = 61/160 (38%), Gaps = 17/160 (10%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTI---NDFG 3613
            PP+F  +P D  ++E S     C+L      S  V W  +  PL T     T+     FG
Sbjct: 2257 PPKFFQSPKDKTVTEKSDVTLTCQLECKPKCS--VTWLKDNTPLDTSPVRITVTHPGSFG 2314

Query: 3614 FVI--LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES 3671
                 L I  + + D   Y+CKA N  G+ T          QG++     P  FK  T +
Sbjct: 2315 NTTSSLTITNLVRTDEARYSCKAINAAGDKT--------SEQGLLTVNFPPRIFK--TSA 2364

Query: 3672 IQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGG 3711
             Q  EE         +E ++   P      KD  DV   G
Sbjct: 2365 NQTREEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADG 2404



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 42/188 (22%), Positives = 63/188 (33%), Gaps = 15/188 (7%)

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
            I+   + K V  G  + F+C       P++ W K    I  S         D  TL +  
Sbjct: 596  IVTHPQPKSVFTGDDVTFTCNATALAAPSIWWQKDGVNITIS---------DGSTLNLVN 646

Query: 4685 AFPEDEGDYKCVAYNSAGRVTV-AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ 4743
                D G+Y CVA       T  AA L V  P    N PA     +    + +       
Sbjct: 647  VKEGDSGNYTCVAEAGENTTTSDAAFLSVKLPPVITNHPA-----NQTANKDENVTIACS 701

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
                    + WL+   +   + D ++    NN  L I      D G++ C  +       
Sbjct: 702  ANGTEPFNVIWLKNNEVYDFSSDSRVHESHNNLTLEIFGVLPNDHGSYQCDVSNGRTDKS 761

Query: 4804 TSAKLVVK 4811
                L+VK
Sbjct: 762  YPGTLIVK 769



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 4/77 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG ++ FEC+ + +  PT  + W  N   L +    +   + ++  L IT+    DSG Y
Sbjct: 876  EGWSVTFECHTKGNPPPT--VTWLKNGSALNTSVDPRFYSNGTH--LMITNVNRTDSGAY 931

Query: 2847 TCKATNSKGSATTSGSL 2863
             C A++  G  TT  SL
Sbjct: 932  RCNASSILGVITTKASL 948



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 7/100 (7%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT----TFFNF 964
            P+F   +K + +  E        +LE  G     V WLKD   ++  SR+     +  + 
Sbjct: 1320 PKFLESLKPKETRNETDNLTLTCKLE--GKPQATVVWLKDNTELKPDSRLIITQPSSVDS 1377

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            G   LTI ++   D   Y CRA N +G   TS+N T+  +
Sbjct: 1378 GESTLTIINLDRSDEASYKCRANNTVG-IVTSSNTTVTVQ 1416



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 7/88 (7%)

Query: 3826 VSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTV-- 3881
            V+ PPKF+  +K   T+ E++ +   C++E K  P   + W + N +L P      T   
Sbjct: 1514 VNYPPKFLQSLKDEETLNETDNLTLTCKLEGK--PLATVVWLKDNTELEPDSRLIITQPS 1571

Query: 3882 -YDMGFVSLDILYVYAEDSGEYICRAVN 3908
              D G  +L I+ V+  D   Y C A N
Sbjct: 1572 SVDSGESTLTIINVHRHDEAYYKCLANN 1599



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/97 (26%), Positives = 37/97 (38%), Gaps = 6/97 (6%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTH----DF 2164
            P FL +L   E L E D     C++E    P  T+ W  +  ++    R   T     D 
Sbjct: 1518 PKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLIITQPSSVDS 1575

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            G   L I+  +  D   Y C A N +    +T    V
Sbjct: 1576 GESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSV 1612



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG+N+   C  E    P+   +WF ++ P  +  +Y +    S  +L  T    +D G Y
Sbjct: 1059 EGENVTLLCVAEGRPSPSY--QWFKDDSPFDA--KYNTRASLSEGNLIFTKVSRDDHGQY 1114

Query: 2847 TCKATNSKGSATTS 2860
             C A NS  + T+S
Sbjct: 1115 YCLANNSVSNVTSS 1128



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 8/94 (8%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDS-SRITKTH 2429
            V +  P F Q  +N + + E       C+L     P   V W ++   ++ S  RIT TH
Sbjct: 1613 VVQYPPKFFQSPKN-ETVTEKSNVTLTCQL--ECKPKCSVTWLKDNTPLDTSPDRITVTH 1669

Query: 2430 DFGY----VSMTISHVRDEDEGVYMCRASNLLGE 2459
               Y     S+TI+++   DE  Y C+A N  GE
Sbjct: 1670 PGSYGNTTSSLTITNLVRTDEARYSCKAINAAGE 1703



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 47/212 (22%), Positives = 80/212 (37%), Gaps = 13/212 (6%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            +G +  + PP      +   + E        E +G+P   + W   + PI+ S   +   
Sbjct: 1708 QGLLTVNYPPKILTPPKNVTITEGNDVTLSCEVEGKPEVTVDWLNGSTPIELSSVIE--- 1764

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
               K+ L +  + + +  +   V+    G+ KC A    +          V    +L  +
Sbjct: 1765 ---KTGLAVTGIGLSNLTI-KGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPE 1820

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI----LEEDGTYTLLILEAY 4577
                 +  L  L  K+ G     V WLK+  +++PD R  I    L E G  TL I+   
Sbjct: 1821 ETRNETDNLT-LTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVN 1879

Query: 4578 PQDSGKYECVAINSAG-EARCDAECVVSLPAT 4608
              D   Y+C A N+    A  +   VV +  T
Sbjct: 1880 RHDEAYYKCRANNTVNTTASTNTSVVVQITVT 1911



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T   +W KD  P +A +      + G +  T   ++  D G Y C A N++   T+S
Sbjct: 979  GRPTPSYQWFKDDSPFDAENNTRASLSEGNLIFT--KISRDDHGQYYCLANNSVSNVTSS 1036

Query: 997  -ANLTIVTKKDI 1007
             A L +  K DI
Sbjct: 1037 IAQLNVFFKPDI 1048



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 7/89 (7%)

Query: 636  PPQFIVPLK-SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF----TSIFR 690
            PP+F+  LK   T  E   +    ++E  G P   + WLK+   ++  SR      S   
Sbjct: 1319 PPKFLESLKPKETRNETDNLTLTCKLE--GKPQATVVWLKDNTELKPDSRLIITQPSSVD 1376

Query: 691  FGYISLDMLSLNIQDSGEYTCRAVSATGV 719
             G  +L +++L+  D   Y CRA +  G+
Sbjct: 1377 SGESTLTIINLDRSDEASYKCRANNTVGI 1405



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 40/156 (25%), Positives = 60/156 (38%), Gaps = 13/156 (8%)

Query: 3542 SGTVDTLTPEAESG----NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
            + TVDT T    +      PP+F  +P +  ++E S+    C+L      S  V W  + 
Sbjct: 1598 NNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCS--VTWLKDN 1655

Query: 3598 KPLLTGSRVKTINDFGFV-----ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
             PL T     T+   G        L I  + + D   Y+CKA N  GE T    L     
Sbjct: 1656 TPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKTSEQGLLTVNY 1715

Query: 3653 QGIILEPQLPSHFKSGTESIQKLEETLHKREEITIE 3688
               IL P        G +     E  +  + E+T++
Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCE--VEGKPEVTVD 1749



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 43/155 (27%), Positives = 62/155 (40%), Gaps = 22/155 (14%)

Query: 1652 CRAINALGEAVTSG-IAIVHSKKSIY---LESQHEGALPRLNQLE----DTSKYQRHSAQ 1703
            C A  A GE +TSG I   H K  I+     +  + + P+++  +     T  Y R    
Sbjct: 528  CLATVAGGENITSGCIKTAHGKCCIFPFVYNATSQYSAPKVDHNKAWCGTTDNYDRDGLW 587

Query: 1704 DEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMH 1763
            D V+    + T P     V       F      +  P   + W ++GV I  S+  T   
Sbjct: 588  DSVLGTLSIVTHPQPK-SVFTGDDVTFTCNATALAAPS--IWWQKDGVNITISDGST--- 641

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
                  LN+  V   DSG YTC  + E GE  T+S
Sbjct: 642  ------LNLVNVKEGDSGNYTC--VAEAGENTTTS 668



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 5/93 (5%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+F    K + +  EG    FE   +  G+ +  V WLK G  V  S  +   F      
Sbjct: 772  PQFIVEPKGKTTT-EGQVVKFEC--QTTGNPSPNVTWLKSGSAVNTS--VDPRFYSNDTI 826

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L I +V+  D+G Y+C A N +G  +  A L +
Sbjct: 827  LMITNVSRIDSGTYSCNASNELGIISAEAALDV 859



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 9/93 (9%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG--SRVHTLNDFGF 3752
            P+F VE K      EG  V F+C+    G+P+  + W  +G    T    R ++ ND   
Sbjct: 772  PQFIVEPKGKTTT-EGQVVKFECQT--TGNPSPNVTWLKSGSAVNTSVDPRFYS-NDTIL 827

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +  ++  I   D+G Y+C A+N+ G  +  A +
Sbjct: 828  MITNVSRI---DSGTYSCNASNELGIISAEAAL 857



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 6/112 (5%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            KP+  T    Q ++ EG         E  G  T   +W KD  P +A +      + G +
Sbjct: 1137 KPDISTHPSPQ-TVTEGENVTLSCAAE--GRPTPSYQWFKDDSPFDAGNNARASLSEGNL 1193

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTS-ANLTIVTKKDIIAESQHPGGLE 1018
              T   V+  D G Y C A N++   T+S   LT+     I    Q+   +E
Sbjct: 1194 IFT--KVSRDDHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTKVE 1243



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 6/128 (4%)

Query: 3410 TSVEEEKGKAPVFTVP--LSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGS 3467
            ++V   K +  VF  P   ++ +N  + E        T T DP   V W  +G +L A  
Sbjct: 1215 SNVTSSKVQLTVFFAPSITTHPQNQTKVEGEIVTLSCTVTGDPVPTVYWSRDGSNLTA-- 1272

Query: 3468 RFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKG 3527
              R   +     L+I     ED G Y+C A+NN     + A++         LES  PK 
Sbjct: 1273 -LRYLVEPSNT-LKIENLTREDEGSYICHAFNNVSSTSSDAAVLTVNYPPKFLESLKPKE 1330

Query: 3528 MEGTIDKI 3535
                 D +
Sbjct: 1331 TRNETDNL 1338



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 8/93 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTL---ND 3749
            PP+F  +I DN+   EG  V+  C++E    P   + W   G    T S R+      ND
Sbjct: 1418 PPKF-FKIPDNVIKTEGSSVNLTCQLEC--KPKCSVTWLIGGSLLDTSSDRISVTQPEND 1474

Query: 3750 FGFIA-LDIDYIYARDAGEYTCRATNKWGSATT 3781
                + L I  +   D   YTCRA N  G  T+
Sbjct: 1475 GNETSFLMISNLNRTDEASYTCRAKNAAGEKTS 1507



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 52/246 (21%), Positives = 92/246 (37%), Gaps = 31/246 (12%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRL----TTM 1762
            +   P    P K++ + E         +   G P++ V+WL    PIE S+ +      +
Sbjct: 1713 VNYPPKILTPPKNVTITEGNDVTLSCEV--EGKPEVTVDWLNGSTPIELSSVIEKTGLAV 1770

Query: 1763 HDFGYVALNMKYVNPEDSGTYTCRA---------------INELGEAVTSSTLFVQSKAS 1807
               G   L +K V+    G+Y CRA               +N LG      T       +
Sbjct: 1771 TGIGLSNLTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLT 1830

Query: 1808 LQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL---SEGQSAHY 1864
            L  + + +  L  +  L+D++  + + D  + + Q P  +       K+   +    A+Y
Sbjct: 1831 LTCKLEGK-PLATVVWLKDNT--ELKPDSRLIITQ-PSLVESGESTLKIINVNRHDEAYY 1886

Query: 1865 ECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINN 1924
            +CR     +            V+Q    +  S     ++L I  +   D   Y+CKAIN 
Sbjct: 1887 KCRANNTVNTTASTN---TSVVVQITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINA 1943

Query: 1925 LGQAVS 1930
             G+  S
Sbjct: 1944 AGEKSS 1949



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 13/103 (12%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D  LG +S   I   P+   +  G D  F    +    P + W K+G   +N      IT
Sbjct: 588 DSVLGTLS---IVTHPQPKSVFTGDDVTFTCNATALAAPSIWWQKDG---VN------IT 635

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAE-NPNGCIVTSGYLAVESP 358
             + +TL + N ++ DSG+YT +AE   N     + +L+V+ P
Sbjct: 636 ISDGSTLNLVNVKEGDSGNYTCVAEAGENTTTSDAAFLSVKLP 678



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 770 PQFIRPLQDLGELQ-EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
           PQFI  ++  G+   EG+   FE Q T   +P+  V W K G  +  S  +   F     
Sbjct: 772 PQFI--VEPKGKTTTEGQVVKFECQTT--GNPSPNVTWLKSGSAVNTS--VDPRFYSNDT 825

Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
            L I ++   D+G+Y+  A N+LG   + A++ V
Sbjct: 826 ILMITNVSRIDSGTYSCNASNELGIISAEAALDV 859



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 6/106 (5%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P   T  ++ T  E E V   C V    DP   + W R+G  L +  RY         +L
Sbjct: 1230 PSITTHPQNQTKVEGEIVTLSCTVTG--DPVPTVYWSRDGSNL-TALRYLVEPSN---TL 1283

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
             I  +  ED G YIC A N+     + A +     P   L++  P+
Sbjct: 1284 KIENLTREDEGSYICHAFNNVSSTSSDAAVLTVNYPPKFLESLKPK 1329



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 4/66 (6%)

Query: 795  TPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEA 854
            T   DP   V W +DG  +TA   +    N    +L I +L  ED GSY   A N +   
Sbjct: 1252 TVTGDPVPTVYWSRDGSNLTALRYLVEPSN----TLKIENLTREDEGSYICHAFNNVSST 1307

Query: 855  ISTASI 860
             S A++
Sbjct: 1308 SSDAAV 1313



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 28/82 (34%), Positives = 35/82 (42%), Gaps = 7/82 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT----HDF 2431
            P    P +N+  I EG      C +   G P + V+W      IE SS I KT       
Sbjct: 1717 PKILTPPKNV-TITEGNDVTLSCEV--EGKPEVTVDWLNGSTPIELSSVIEKTGLAVTGI 1773

Query: 2432 GYVSMTISHVRDEDEGVYMCRA 2453
            G  ++TI  V    EG Y CRA
Sbjct: 1774 GLSNLTIKGVSRYYEGSYKCRA 1795



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 9/76 (11%)

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
           +V  G+ V     A     P I WQKDGV I         T    STL++   K  D+  
Sbjct: 604 SVFTGDDVTFTCNATALAAPSIWWQKDGVNI---------TISDGSTLNLVNVKEGDSGN 654

Query: 561 YQCTAQNVAGSTATRA 576
           Y C A+    +T + A
Sbjct: 655 YTCVAEAGENTTTSDA 670



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)

Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            EGQ   F+C+    G+P+  V W ++   +  S  +          + I++V   D G Y
Sbjct: 785  EGQVVKFECQT--TGNPSPNVTWLKSGSAVNTS--VDPRFYSNDTILMITNVSRIDSGTY 840

Query: 2450 MCRASNLLG 2458
             C ASN LG
Sbjct: 841  SCNASNELG 849



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            +   P F    +D    E  +  FE      G+P   V WL+NG  +  S      +  G
Sbjct: 859  VRYGPEFVNVPQDKTPNEGWSVTFECHT--KGNPPPTVTWLKNGSALNTSVD-PRFYSNG 915

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
               L +  VN  DSG Y C A + LG   T ++L V  K  +
Sbjct: 916  -THLMITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 5/91 (5%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P  ++EGQ+    C  E  P P+   +W+ +     + +  R S   G   L    +  +
Sbjct: 962  PQTVTEGQNVTLLCVAEGRPTPSY--QWFKDDSPFDAENNTRASLSEG--NLIFTKISRD 1017

Query: 1913 DSGEYTCKAINNLGQAVSSI-RLNVQSKESI 1942
            D G+Y C A N++    SSI +LNV  K  I
Sbjct: 1018 DHGQYYCLANNSVSNVTSSIAQLNVFFKPDI 1048



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 37/155 (23%), Positives = 58/155 (37%), Gaps = 6/155 (3%)

Query: 1261 AHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNI 1320
            A  +A   + E + I T    +   +   L  ++       +  +TV  AP  +    N 
Sbjct: 1180 AGNNARASLSEGNLIFTKVSRDDHGQYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQ 1239

Query: 1321 ETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
              VEG  V L C +   GD    V W  +G  + T  R+          L + ++  ED 
Sbjct: 1240 TKVEGEIVTLSCTV--TGDPVPTVYWSRDGSNL-TALRYLVEPSN---TLKIENLTREDE 1293

Query: 1381 GVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
            G Y C A N +    +  A+  +      LES  P
Sbjct: 1294 GSYICHAFNNVSSTSSDAAVLTVNYPPKFLESLKP 1328



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 6/98 (6%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR----Y 1893
            + VN  P+F+  L      +E  +    C++E    P   V W  +   L+   R     
Sbjct: 1314 LTVNYPPKFLESLKPKETRNETDNLTLTCKLE--GKPQATVVWLKDNTELKPDSRLIITQ 1371

Query: 1894 RTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
             +S D G + L I+ +   D   Y C+A N +G   SS
Sbjct: 1372 PSSVDSGESTLTIINLDRSDEASYKCRANNTVGIVTSS 1409



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 9/127 (7%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ-SGHRYRTS 1896
            V V   P+F    +   K +EG S +  C++E    P   V W   G +L  S  R   +
Sbjct: 1413 VTVQYPPKFFKIPDNVIK-TEGSSVNLTCQLEC--KPKCSVTWLIGGSLLDTSSDRISVT 1469

Query: 1897 ---NDFGFAA-LDILTVYGEDSGEYTCKAINNLGQAVS-SIRLNVQSKESIIRDSQHESA 1951
               ND    + L I  +   D   YTC+A N  G+  S S+ L V      ++  + E  
Sbjct: 1470 QPENDGNETSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEET 1529

Query: 1952 LEKIQYL 1958
            L +   L
Sbjct: 1530 LNETDNL 1536



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 16/46 (34%), Positives = 22/46 (47%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            PP F  +PD V   EG      C++   PK  V WL+ G+ +   S
Sbjct: 1418 PPKFFKIPDNVIKTEGSSVNLTCQLECKPKCSVTWLIGGSLLDTSS 1463



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 5/99 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F V +  +    EG  V F+C  +  G+P   + W  NG    T       ++   + 
Sbjct: 863  PEF-VNVPQDKTPNEGWSVTFECHTK--GNPPPTVTWLKNGSALNTSVDPRFYSNGTHLM 919

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDI 3793
              I  +   D+G Y C A++  G  TT A +    K DI
Sbjct: 920  --ITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 57/235 (24%), Positives = 94/235 (40%), Gaps = 41/235 (17%)

Query: 1431 KKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIG 1490
            K +  ++ +V   P+F+   K  E + E  ++   CKLE    +   V W K+   +   
Sbjct: 1505 KTSGSVNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLEGKPLAT--VVWLKDNTELEPD 1562

Query: 1491 HRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
             R           L I    + DSG  T   +N+   DE   +    +T D   ST N +
Sbjct: 1563 SR-----------LIITQPSSVDSGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTS 1611

Query: 1551 GLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLK 1610
                  V++   K+ ++   + VT ++ +  T    +E K                    
Sbjct: 1612 -----VVVQYPPKFFQSPKNETVTEKSNVTLTC--QLECKP----------------KCS 1648

Query: 1611 VEWYHNNKPLK-SGSRFTETN--NFGFV--ALDIMSCLPEDSGTYTCRAINALGE 1660
            V W  +N PL  S  R T T+  ++G    +L I + +  D   Y+C+AINA GE
Sbjct: 1649 VTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGE 1703



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 8/73 (10%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITT------FFNFGYVALTIKSVTVHDAGHYTCRAYNAI 990
            G S   V W KDG  V A    TT      +      +LTIK+V   D G Y C A N++
Sbjct: 2385 GTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSL 2444

Query: 991  G--QATTSANLTI 1001
                +T S +LT+
Sbjct: 2445 KTVYSTPSIHLTV 2457



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 5/97 (5%)

Query: 1847 ITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI 1906
            I+    P  ++EG++    C  E  P P+   +W+ +     +  +Y T        L  
Sbjct: 1048 ISTYPSPQTITEGENVTLLCVAEGRPSPSY--QWFKDDSPFDA--KYNTRASLSEGNLIF 1103

Query: 1907 LTVYGEDSGEYTCKAINNLGQAVSSI-RLNVQSKESI 1942
              V  +D G+Y C A N++    SSI +L V  K  I
Sbjct: 1104 TKVSRDDHGQYYCLANNSVSNVTSSIAKLTVFFKPDI 1140



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 33/137 (24%), Positives = 52/137 (37%), Gaps = 12/137 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I     TD  +Y+CRA N  G+         V+ +    P+F   +++ E L +  + 
Sbjct: 1481 LMISNLNRTDEASYTCRAKNAAGEKTSG----SVNLAVNYPPKFLQSLKDEETLNETDNL 1536

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRI----KTVSDFGFVVLDIAYTQNHDSGEYV 3223
               C +     P   + W  +   +   +R+     +  D G   L I     HD   Y 
Sbjct: 1537 TLTCKL--EGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYK 1594

Query: 3224 CRAYNKYGEDFTRATIN 3240
            C A N    D T +T N
Sbjct: 1595 CLANNTV--DTTTSTTN 1609



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 89/390 (22%), Positives = 144/390 (36%), Gaps = 63/390 (16%)

Query: 1295 ARRTKQVREDITVMQAPQFSRALHNIETVEGT-NVHLECRLQPVGDQTMRVEWFCNGKPI 1353
            A+R     E         F  +L   ET   T N+ L C+L+  G     V W  +   +
Sbjct: 1795 AKRDPDTSESDPAYITVNFLGSLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTEL 1852

Query: 1354 KTGHRF---RPAY-EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409
            K   R    +P+  E     L +++V   D   Y C+A N +     S    V+ +  + 
Sbjct: 1853 KPDSRLIITQPSLVESGESTLKIINVNRHDEAYYKCRANNTVN-TTASTNTSVVVQITVT 1911

Query: 1410 LESQHPSGLEKIQYLE----DTSRY--KKTDIIDE--------SVTIKPRFVTRPKSIEN 1455
                + +    +        D +RY  K  +   E        +V   P+F+   K  E 
Sbjct: 1912 HPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPEET 1971

Query: 1456 VIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSG 1515
              E  ++   CKLE    +   V W K+   +    R           L I    + DSG
Sbjct: 1972 RNETDNLTLTCKLEGKPLAT--VVWLKDNTELKPDSR-----------LIITQPSSVDSG 2018

Query: 1516 IYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTT 1575
              T   +N+   DE   +    +T D   ST N +      V++   K+ ++   + VT 
Sbjct: 2019 ESTLTIINVNRHDEAYYKCRANNTVDTTTSTTNTS-----VVVQYPPKFFQSPKNETVTE 2073

Query: 1576 QAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLK-SGSRFTETN--NF 1632
            ++ +  T    +E K                    V W  +N PL  S  R T T+  ++
Sbjct: 2074 KSNVTLTC--QLECKP----------------KCSVTWLKDNTPLDTSPDRITVTHPGSY 2115

Query: 1633 GFV--ALDIMSCLPEDSGTYTCRAINALGE 1660
            G    +L I + +  D   Y+C+AINA GE
Sbjct: 2116 GNTTSSLTITNLVRTDEARYSCKAINAAGE 2145



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 7/101 (6%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPK-LRIEWYRNG-KLLPSGHRYRTVYD 3883
            V+ PP+      + T EE + + F C VE KE      + W ++G  +   G+R      
Sbjct: 2353 VNFPPRIFKTSANQTREEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTAQSP 2412

Query: 3884 MGFV-----SLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
              ++     SL I  V  ED G Y C A N     ++  +I
Sbjct: 2413 TNYMGPSTASLTIKNVQREDEGFYQCFAENSLKTVYSTPSI 2453



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P+F+ E +G T   EG+   FECQ      PN  + +  +G A+ ++      F      
Sbjct: 772  PQFIVEPKGKTTT-EGQVVKFECQTTGNPSPN--VTWLKSGSAVNTSV--DPRFYSNDTI 826

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
            L I +    D+G YS  A N LG  ++  ++ V
Sbjct: 827  LMITNVSRIDSGTYSCNASNELGIISAEAALDV 859



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 5/88 (5%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P  +TH  S   + EGQ+V L    E R  P+   +WFK+          +++   G   
Sbjct: 954  PDISTH-PSPQTVTEGQNVTLLCVAEGRPTPSY--QWFKDDSPFDAENNTRASLSEG--N 1008

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVST 2729
            L    +  DD G Y C A N +    S+
Sbjct: 1009 LIFTKISRDDHGQYYCLANNSVSNVTSS 1036



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG N+   C  E    PT   +WF ++ P  +    +++   S  +L  T    +D G Y
Sbjct: 967  EGQNVTLLCVAEGR--PTPSYQWFKDDSPFDAENNTRAS--LSEGNLIFTKISRDDHGQY 1022

Query: 2847 TCKATNSKGSATTS 2860
             C A NS  + T+S
Sbjct: 1023 YCLANNSVSNVTSS 1036



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 34/137 (24%), Positives = 50/137 (36%), Gaps = 12/137 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I     TD   YSC+A N  G+      L  V+      P+F   ++  E   +  + 
Sbjct: 1923 LTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN----YPPKFLESLKPEETRNETDNL 1978

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVS----DFGFVVLDIAYTQNHDSGEYV 3223
               C +     P   + W  +   ++  +R+        D G   L I     HD   Y 
Sbjct: 1979 TLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINVNRHDEAYYK 2036

Query: 3224 CRAYNKYGEDFTRATIN 3240
            CRA N    D T +T N
Sbjct: 2037 CRANNTV--DTTTSTTN 2051



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 9/99 (9%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRF----KTYYDF 1232
            P F++ L      +E  N+ L C+LE  G P   V W  +   +   SR      +  + 
Sbjct: 2159 PKFLESLKPEETRNETDNLTLTCKLE--GKPLATVVWLKDNTELKPDSRLIITQPSLVES 2216

Query: 1233 GFVALDIIHATSADTGEYTVRA---VNHLGSAHTSAIVR 1268
            G   L II+    D   Y  RA   VN   S +TS +V+
Sbjct: 2217 GESTLKIINVNRHDEAYYKCRANNTVNTTASTNTSVVVQ 2255



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH----DF 2431
            P F + L+  +   E       C+L   G P   V W ++   ++  SR+  T     + 
Sbjct: 2159 PKFLESLKPEETRNETDNLTLTCKL--EGKPLATVVWLKDNTELKPDSRLIITQPSLVES 2216

Query: 2432 GYVSMTISHVRDEDEGVYMCRASN 2455
            G  ++ I +V   DE  Y CRA+N
Sbjct: 2217 GESTLKIINVNRHDEAYYKCRANN 2240



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 26/116 (22%), Positives = 41/116 (35%), Gaps = 5/116 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP       + T  + E V   C     E     + W +N ++       R      
Sbjct: 675  VKLPPVITNHPANQTANKDENVTIACSANGTEP--FNVIWLKNNEVYDFSSDSRVHESHN 732

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSE 3941
             ++L+I  V   D G Y C   N   +     T+  K  P  I++   P+G   +E
Sbjct: 733  NLTLEIFGVLPNDHGSYQCDVSNGRTDKSYPGTLIVKYAPQFIVE---PKGKTTTE 785



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+F+   QD T   EG S  FE       +P   V W  NG  L      R F+  G  +
Sbjct: 863  PEFVNVPQDKTPN-EGWSVTFECHTK--GNPPPTVTWLKNGSALNTSVDPR-FYSNGTHL 918

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
            + I      +SG Y C A++ LG  +TKA+L    K ++
Sbjct: 919  M-ITNVNRTDSGAYRCNASSILGVITTKASLDVYFKPDI 956



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 4/69 (5%)

Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            EG +  F+C     G+P   V W +N   + ++S   + +  G   + I++V   D G Y
Sbjct: 876  EGWSVTFECHT--KGNPPPTVTWLKNGSAL-NTSVDPRFYSNG-THLMITNVNRTDSGAY 931

Query: 2450 MCRASNLLG 2458
             C AS++LG
Sbjct: 932  RCNASSILG 940



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 28/101 (27%), Positives = 38/101 (37%), Gaps = 5/101 (4%)

Query: 3707 VPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAG 3766
            V EG  V   C  E  G PT    WF +  PF  G+        G   L    +   D G
Sbjct: 1149 VTEGENVTLSCAAE--GRPTPSYQWFKDDSPFDAGNNARASLSEG--NLIFTKVSRDDHG 1204

Query: 3767 EYTCRATNKWGSATTT-AKITCSAKRDIVLESQLPQGMSGE 3806
            +Y C A N   + T++  ++T      I    Q    + GE
Sbjct: 1205 QYYCLANNSVSNVTSSKVQLTVFFAPSITTHPQNQTKVEGE 1245



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 4/66 (6%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMH----DFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G P+  V WL++   ++  +RL        D G   L +  ++  D  +Y CRA N +G 
Sbjct: 1346 GKPQATVVWLKDNTELKPDSRLIITQPSSVDSGESTLTIINLDRSDEASYKCRANNTVGI 1405

Query: 1794 AVTSST 1799
              +S+T
Sbjct: 1406 VTSSNT 1411



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/93 (25%), Positives = 37/93 (39%), Gaps = 6/93 (6%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN----D 3749
            PP+F   +KD   + E   +   C++E  G P   + W  +       SR+        D
Sbjct: 1517 PPKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLIITQPSSVD 1574

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
             G   L I  ++  D   Y C A N   + T+T
Sbjct: 1575 SGESTLTIINVHRHDEAYYKCLANNTVDTTTST 1607



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT 4150
            PP  ++ P  VT+ EG      C V G P+  V W LNG+T
Sbjct: 1716 PPKILTPPKNVTITEGNDVTLSCEVEGKPEVTVDW-LNGST 1755



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 36/126 (28%), Positives = 51/126 (40%), Gaps = 10/126 (7%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNM-RVEWYFNGK-VLQSGHRYRT 1895
            + VN  PR        T+  EGQ   + C +E     +   V W  +G  V   G+R   
Sbjct: 2351 LTVNFPPRIFKTSANQTR-EEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTA 2409

Query: 1896 SNDFGF-----AALDILTVYGEDSGEYTCKAINNLGQAVS--SIRLNVQSKESIIRDSQH 1948
             +   +     A+L I  V  ED G Y C A N+L    S  SI L V    +I   S  
Sbjct: 2410 QSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSLKTVYSTPSIHLTVHFNSTIFECSGA 2469

Query: 1949 ESALEK 1954
            ++  E+
Sbjct: 2470 QNVTER 2475



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 4/78 (5%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD    V W +DG  + A   +    N     L I+++T  D G Y C A+N +   ++ 
Sbjct: 1255 GDPVPTVYWSRDGSNLTALRYLVEPSN----TLKIENLTREDEGSYICHAFNNVSSTSSD 1310

Query: 997  ANLTIVTKKDIIAESQHP 1014
            A +  V       ES  P
Sbjct: 1311 AAVLTVNYPPKFLESLKP 1328



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 9/81 (11%)

Query: 2386 DNI--QEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSS-RITKT---HDFGYVS-MTI 2438
            DN+   EG + +  C+L     P   V W     L++ SS RI+ T   +D    S + I
Sbjct: 1426 DNVIKTEGSSVNLTCQL--ECKPKCSVTWLIGGSLLDTSSDRISVTQPENDGNETSFLMI 1483

Query: 2439 SHVRDEDEGVYMCRASNLLGE 2459
            S++   DE  Y CRA N  GE
Sbjct: 1484 SNLNRTDEASYTCRAKNAAGE 1504



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/104 (24%), Positives = 39/104 (37%), Gaps = 2/104 (1%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP  T  P++   +++ +    C           V W  N +     S  +       + 
Sbjct: 678  PPVITNHPANQTANKDENVTIACSAN--GTEPFNVIWLKNNEVYDFSSDSRVHESHNNLT 735

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
            LEI GV   D G Y C  +N   + +    L VK     I+EP+
Sbjct: 736  LEIFGVLPNDHGSYQCDVSNGRTDKSYPGTLIVKYAPQFIVEPK 779



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGF- 3477
            AP F V     +   EG+   FE + T    PN  V W      LK+GS   T  D  F 
Sbjct: 771  APQFIVEPKG-KTTTEGQVVKFECQTTGNPSPN--VTW------LKSGSAVNTSVDPRFY 821

Query: 3478 ---VILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
                IL I+     DSG Y C A N  G     A++ V+
Sbjct: 822  SNDTILMITNVSRIDSGTYSCNASNELGIISAEAALDVR 860



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 6/97 (6%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            PQF    K    TEG  V  E   T   +P+  V W  +G  V         +      L
Sbjct: 772  PQFIVEPKGKTTTEGQVVKFECQTT--GNPSPNVTWLKSGSAVNTS--VDPRFYSNDTIL 827

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSG 2074
             I      D+GTY C A+N +G  + ++   +D + G
Sbjct: 828  MITNVSRIDSGTYSCNASNELG--IISAEAALDVRYG 862



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 12/81 (14%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD----ITHTYEED 2842
            EG  + FEC  + + +P+  + W      L SG+   ++ D  + S D    IT+    D
Sbjct: 785  EGQVVKFEC--QTTGNPSPNVTW------LKSGSAVNTSVDPRFYSNDTILMITNVSRID 836

Query: 2843 SGIYTCKATNSKGSATTSGSL 2863
            SG Y+C A+N  G  +   +L
Sbjct: 837  SGTYSCNASNELGIISAEAAL 857



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 34/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P   T     T+ E E V   C  E +  P    +W+++    P   +Y T   +   +L
Sbjct: 1046 PDISTYPSPQTITEGENVTLLCVAEGRPSPSY--QWFKDDS--PFDAKYNTRASLSEGNL 1101

Query: 3890 DILYVYAEDSGEYICRA---VNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQM 3946
                V  +D G+Y C A   V++      K T+  K  PD I  +  P+ +   E +T  
Sbjct: 1102 IFTKVSRDDHGQYYCLANNSVSNVTSSIAKLTVFFK--PD-ISTHPSPQTVTEGENVTLS 1158

Query: 3947 EATIKKYTSEVYLTEDD 3963
             A   + T      +DD
Sbjct: 1159 CAAEGRPTPSYQWFKDD 1175



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 6/78 (7%)

Query: 1611 VEWYHNNKPLKSGS-RFTETN--NFGFV--ALDIMSCLPEDSGTYTCRAINALGEAVT-S 1664
            V W  +N PL +   R T T+  +FG    +L I + +  D   Y+C+AINA G+  +  
Sbjct: 2289 VTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAINAAGDKTSEQ 2348

Query: 1665 GIAIVHSKKSIYLESQHE 1682
            G+  V+    I+  S ++
Sbjct: 2349 GLLTVNFPPRIFKTSANQ 2366



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 9/87 (10%)

Query: 2656 EGQHVYLEAQVEPR--TDPNLKIEWFKNGVTLTT-GARL--KSTFDF---GLVTLSINSL 2707
            EGQ +     VE +  T P   + W K+G  +T  G R   +S  ++      +L+I ++
Sbjct: 2370 EGQQITFTCDVEGKEGTSPP-NVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNV 2428

Query: 2708 RNDDSGIYTCKATNLLGEAVSTASIKI 2734
            + +D G Y C A N L    ST SI +
Sbjct: 2429 QREDEGFYQCFAENSLKTVYSTPSIHL 2455



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/124 (22%), Positives = 48/124 (38%), Gaps = 5/124 (4%)

Query: 2606 IIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQ 2665
            I  +  R +  +   L   +++ V        V   P  +T+  S   + EG++V L   
Sbjct: 1010 IFTKISRDDHGQYYCLANNSVSNVTSSIAQLNVFFKPDISTY-PSPQTITEGENVTLLCV 1068

Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE 2725
             E R  P+   +WFK+          +++   G   L    +  DD G Y C A N +  
Sbjct: 1069 AEGRPSPSY--QWFKDDSPFDAKYNTRASLSEG--NLIFTKVSRDDHGQYYCLANNSVSN 1124

Query: 2726 AVST 2729
              S+
Sbjct: 1125 VTSS 1128



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
            EG NV L C  +  G  +   +WF +  P    +  R +     +    +S   +D G Y
Sbjct: 1059 EGENVTLLCVAE--GRPSPSYQWFKDDSPFDAKYNTRASLSEGNLIFTKVS--RDDHGQY 1114

Query: 1384 TCQATNQLGEAVTSCA-LRVIAKKDLILESQHPS 1416
             C A N +    +S A L V  K D+   S HPS
Sbjct: 1115 YCLANNSVSNVTSSIAKLTVFFKPDI---STHPS 1145



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 29/111 (26%), Positives = 41/111 (36%), Gaps = 7/111 (6%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P   T  Q+QT  VE E     C +   GDP   V W  +G  L          +     
Sbjct: 1230 PSITTHPQNQTK-VEGEIVTLSCTVT--GDPVPTVYWSRDGSNLTALRYLVEPSN----T 1282

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKS 4083
            +    +  ED G Y+C A N      + A + T   P    +S  PK  ++
Sbjct: 1283 LKIENLTREDEGSYICHAFNNVSSTSSDAAVLTVNYPPKFLESLKPKETRN 1333



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%)

Query: 2406 PTLKVEWFRNEKLIEDSS-RITKTH--DFGYV--SMTISHVRDEDEGVYMCRASNLLGE 2459
            P   V W ++   ++ S  RIT TH   FG    S+TI+++   DE  Y C+A N  G+
Sbjct: 2285 PKCSVTWLKDNTPLDTSPVRITVTHPGSFGNTTSSLTITNLVRTDEARYSCKAINAAGD 2343



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 7/76 (9%)

Query: 2389 QEGQTAHFDCRLI-PVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYV-----SMTISHV 2441
            +EGQ   F C +    G     V W ++   +  D +R T      Y+     S+TI +V
Sbjct: 2369 EEGQQITFTCDVEGKEGTSPPNVYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNV 2428

Query: 2442 RDEDEGVYMCRASNLL 2457
            + EDEG Y C A N L
Sbjct: 2429 QREDEGFYQCFAENSL 2444



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 6/72 (8%)

Query: 804  VEWYKDGRPITA-SSRITSIFNFGYV-----SLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
            V W KDG  +TA  +R T+     Y+     SL I +++ ED G Y   A N L    ST
Sbjct: 2391 VYWKKDGADVTADGNRTTAQSPTNYMGPSTASLTIKNVQREDEGFYQCFAENSLKTVYST 2450

Query: 858  ASIRVAARSTVT 869
             SI +      T
Sbjct: 2451 PSIHLTVHFNST 2462



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
            EG NV L C  +  G  T   +WF +  P    +  R +     +    +S   +D G Y
Sbjct: 967  EGQNVTLLCVAE--GRPTPSYQWFKDDSPFDAENNTRASLSEGNLIFTKIS--RDDHGQY 1022

Query: 1384 TCQATNQLGEAVTSCA-LRVIAKKDLILESQHPS 1416
             C A N +    +S A L V  K D+   S +PS
Sbjct: 1023 YCLANNSVSNVTSSIAQLNVFFKPDI---STYPS 1053



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 5/93 (5%)

Query: 1977 KPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            KP          VTEG  V L         PT   +W+ +  P   G+  + +   G   
Sbjct: 1137 KPDISTHPSPQTVTEGENVTLSCAAE--GRPTPSYQWFKDDSPFDAGNNARASLSEGN-- 1192

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            L       +D G Y C A N+V   VT+S V++
Sbjct: 1193 LIFTKVSRDDHGQYYCLANNSVSN-VTSSKVQL 1224



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 10/97 (10%)

Query: 911  FKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASS---RITTFFNFGYV 967
            FK P  D +   EG   +   +LE        V WL  G  ++ SS    +T   N G  
Sbjct: 1422 FKIP--DNVIKTEGSSVNLTCQLEC--KPKCSVTWLIGGSLLDTSSDRISVTQPENDGNE 1477

Query: 968  A--LTIKSVTVHDAGHYTCRAYNAIGQATT-SANLTI 1001
               L I ++   D   YTCRA NA G+ T+ S NL +
Sbjct: 1478 TSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAV 1514



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 37/130 (28%), Positives = 51/130 (39%), Gaps = 9/130 (6%)

Query: 1937 QSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVE-KPQFGKPIKNAEVTEGHPV 1995
            +S  +II   +H+ A  K     +      +  + S VV+  P+F +  KN  VTE   V
Sbjct: 1577 ESTLTIINVHRHDEAYYKC-LANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNV 1635

Query: 1996 HLEATLTPVNDPTMRVEWYCNGRPVQQG-HRFKTTYDFGY----VALDILYAYAEDTGTY 2050
             L   L     P   V W  +  P+     R   T+   Y     +L I      D   Y
Sbjct: 1636 TLTCQLEC--KPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARY 1693

Query: 2051 MCKATNAVGE 2060
             CKA NA GE
Sbjct: 1694 SCKAINAAGE 1703



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 42/190 (22%), Positives = 67/190 (35%), Gaps = 21/190 (11%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR----TVYA 3102
            PP+  T  K++  I+EG        +   G   + ++W      IE S  I      V  
Sbjct: 1716 PPKILTPPKNVT-ITEGNDVTLSCEV--EGKPEVTVDWLNGSTPIELSSVIEKTGLAVTG 1772

Query: 3103 FGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLK 3162
             G+  L I G      G+Y CRA      +E       V+     KP  T +        
Sbjct: 1773 IGLSNLTIKGVSRYYEGSYKCRAKRDPDTSESDPAYITVNFLGSLKPEETRN-------- 1824

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI----KTVSDFGFVVLDIAYTQNHD 3218
              ++ +   T      P   + W  +   ++  +R+     ++ + G   L I     HD
Sbjct: 1825 --ETDNLTLTCKLEGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHD 1882

Query: 3219 SGEYVCRAYN 3228
               Y CRA N
Sbjct: 1883 EAYYKCRANN 1892



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 8/113 (7%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA-RFHITFDFGY 2299
            PP+F    +  T V E       CQ+E    P   + +  +   L ++  R  +T    Y
Sbjct: 2059 PPKFFQSPKNET-VTEKSNVTLTCQLEC--KPKCSVTWLKDNTPLDTSPDRITVTHPGSY 2115

Query: 2300 ----VSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPE 2348
                 SL I + V  D   YS KAINA G  +S   +          ES +PE
Sbjct: 2116 GNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLESLKPE 2168



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 29/125 (23%), Positives = 47/125 (37%), Gaps = 10/125 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I     TD   YSC+A N  G+      L  V+      P+F   ++  E   +  + 
Sbjct: 2122 LTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN----YPPKFLESLKPEETRNETDNL 2177

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRI----KTVSDFGFVVLDIAYTQNHDSGEYV 3223
               C +     P   + W  +   ++  +R+     ++ + G   L I     HD   Y 
Sbjct: 2178 TLTCKL--EGKPLATVVWLKDNTELKPDSRLIITQPSLVESGESTLKIINVNRHDEAYYK 2235

Query: 3224 CRAYN 3228
            CRA N
Sbjct: 2236 CRANN 2240



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/95 (30%), Positives = 38/95 (40%), Gaps = 7/95 (7%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            V++ V  AP   T     TK+ EG+     C +   P P   V W  +G  L +  RY  
Sbjct: 1222 VQLTVFFAPSITTHPQNQTKV-EGEIVTLSCTVTGDPVPT--VYWSRDGSNL-TALRYLV 1277

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
                    L I  +  ED G Y C A NN+    S
Sbjct: 1278 EPS---NTLKIENLTREDEGSYICHAFNNVSSTSS 1309



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 15/41 (36%), Positives = 19/41 (46%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P   + P   T  EGE     C VTG P P V W  +G+ +
Sbjct: 1230 PSITTHPQNQTKVEGEIVTLSCTVTGDPVPTVYWSRDGSNL 1270



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 11/105 (10%)

Query: 636  PPQFIVPLKSV-TAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF----TSIFR 690
            PP+F+  LK   T  E   +    ++E  G P   + WLK+   +E  SR      S   
Sbjct: 1517 PPKFLQSLKDEETLNETDNLTLTCKLE--GKPLATVVWLKDNTELEPDSRLIITQPSSVD 1574

Query: 691  FGYISLDMLSLNIQDSGEYTCRA----VSATGVAETKAVLHVTPR 731
             G  +L +++++  D   Y C A     + T    T  V+   P+
Sbjct: 1575 SGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSVVVQYPPK 1619



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 5/91 (5%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+FI + +  T   EGQ   FE +     +P   V W  +G  +      R + +    I
Sbjct: 772  PQFIVEPKGKTT-TEGQVVKFECQTT--GNPSPNVTWLKSGSAVNTSVDPRFYSND--TI 826

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            L I      +SG Y C A+N+LG  S +A L
Sbjct: 827  LMITNVSRIDSGTYSCNASNELGIISAEAAL 857



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 4/69 (5%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG    FEC+      P++T  W  +G  +      R   +     L I      DSGTY
Sbjct: 785  EGQVVKFECQTTGNPSPNVT--WLKSGSAVNTSVDPRFYSND--TILMITNVSRIDSGTY 840

Query: 2183 MCKATNKLG 2191
             C A+N+LG
Sbjct: 841  SCNASNELG 849



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/85 (23%), Positives = 29/85 (34%), Gaps = 2/85 (2%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P I+  P    + EG +        G P P   WFK+       N      +  +  L  
Sbjct: 1138 PDISTHPSPQTVTEGENVTLSCAAEGRPTPSYQWFKDDSPFDAGNNARASLSEGN--LIF 1195

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTS 350
                + D G Y  LA N    + +S
Sbjct: 1196 TKVSRDDHGQYYCLANNSVSNVTSS 1220



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 8/93 (8%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAA-RFHITFDFGY 2299
            PP+F    +  T V E       CQ+E    P   + +  +   L ++  R  +T    Y
Sbjct: 1617 PPKFFQSPKNET-VTEKSNVTLTCQLEC--KPKCSVTWLKDNTPLDTSPDRITVTHPGSY 1673

Query: 2300 ----VSLDIQHCVPEDAGEYSVKAINALGHCTS 2328
                 SL I + V  D   YS KAINA G  TS
Sbjct: 1674 GNTTSSLTITNLVRTDEARYSCKAINAAGEKTS 1706


>SB_23359| Best HMM Match : I-set (HMM E-Value=0)
          Length = 367

 Score =  100 bits (239), Expect = 3e-20
 Identities = 101/377 (26%), Positives = 164/377 (43%), Gaps = 45/377 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W R+  PI N+ D         ++L I   F  DS  +A  A N  GTA+  
Sbjct: 32   GMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAI 91

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVN-VTSGQLVRLDTKVTGTKPIDVYWL-KNGKK 4553
            A L V+ +          P  T++    + V +G+ V L   VTG     + W+  N   
Sbjct: 92   AVLNVKAE----------PQVTVSPSRQHYVATGRQVELLCTVTGYPVPSIEWIVPNRTG 141

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPK 4613
            + P +   +    G   ++I        G+Y C+A N+ G A    E VV L    +  +
Sbjct: 142  LSPSL---VKVAQGVLKIVIENVTSPYEGRYRCMAKNNLGTA----EEVVQLFVVPNVTR 194

Query: 4614 PQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR 4673
            P   +       ++P+  K+V +G    F+C   G P P + W   ++L   +K  + + 
Sbjct: 195  PNNVS-------VQPVNQKVV-KGNTATFNCTASGVPTPQLVW---ERL--GAKMPETAM 241

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
            T+D+  L I     +D G+Y+C+A NS G   V AKL+V  P       A++P + + + 
Sbjct: 242  TSDKGLLTIESVGADDSGEYECIATNSEGSERVLAKLEVIVPPDV----AVSP-QQVSIN 296

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
             G+P  F+    S     + W +    I  +    ++  G   VL++     +DTG + C
Sbjct: 297  LGRP--FRLFCVSNPPLPLTWSKVNGTISNS---SVVVGG---VLIVQEAIIQDTGKYRC 348

Query: 4794 RATTAAGQVETSAKLVV 4810
             A+  AG  E  A + V
Sbjct: 349  HASNIAGSDEGFAMVTV 365



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 56/202 (27%), Positives = 85/202 (42%), Gaps = 12/202 (5%)

Query: 379 TEERIEISEKALAPQF-VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYN 437
           T E I +      PQ  V   +   V  G+     C VTG P P + W + +   R   +
Sbjct: 87  TAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVELLCTVTGYPVPSIEWIVPN---RTGLS 143

Query: 438 HKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE-R 496
             ++    G   ++I NVT    G   C+A+N  G      +L V+    V  P  V  +
Sbjct: 144 PSLVKVAQGVLKIVIENVTSPYEGRYRCMAKNNLGTAEEVVQLFVV--PNVTRPNNVSVQ 201

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
                V +G     N  A G PTP++ W++ G  +   PE  + +D G  T++     A 
Sbjct: 202 PVNQKVVKGNTATFNCTASGVPTPQLVWERLGAKM---PETAMTSDKGLLTIE--SVGAD 256

Query: 557 DAAWYQCTAQNVAGSTATRARL 578
           D+  Y+C A N  GS    A+L
Sbjct: 257 DSGEYECIATNSEGSERVLAKL 278



 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 47/190 (24%), Positives = 78/190 (41%), Gaps = 7/190 (3%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKI-VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            P   I+P   + VA G+ + F C +  G P P + W +  + I  ++    +   +   L
Sbjct: 5    PVVSIQPSPQQTVAGGETVVFRCAVNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVL 64

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            +I+ AF  D G Y C A N  G     A L V    +A+    ++P R   V  G+  + 
Sbjct: 65   KIAHAFDSDSGRYACRATNLLGTAEAIAVLNV----KAEPQVTVSPSRQHYVATGRQVEL 120

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
               +T    P+I+W+        +P    + +G    ++I N      G + C A    G
Sbjct: 121  LCTVTGYPVPSIEWIVPNR-TGLSPSLVKVAQG-VLKIVIENVTSPYEGRYRCMAKNNLG 178

Query: 4801 QVETSAKLVV 4810
              E   +L V
Sbjct: 179  TAEEVVQLFV 188



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 54/220 (24%), Positives = 85/220 (38%), Gaps = 20/220 (9%)

Query: 353 LAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ-DRDVTEGKMTRF 411
           + +E+ T  Y    R     +    E   ++ +      P  V V   ++ V +G    F
Sbjct: 156 IVIENVTSPYEGRYRCMAKNNLGTAEEVVQLFVVPNVTRPNNVSVQPVNQKVVKGNTATF 215

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           +C  +G P P++ W     ++        + ++ G   L I +V   DSG   C+A N  
Sbjct: 216 NCTASGVPTPQLVW----ERLGAKMPETAMTSDKG--LLTIESVGADDSGEYECIATNSE 269

Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
           G      +L VI     V P        +++  G P  L    V  P   +TW K     
Sbjct: 270 GSERVLAKLEVI-----VPPDVAVSPQQVSINLGRPFRL--FCVSNPPLPLTWSKVN-GT 321

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
           I N  + +   GG   L +  A   D   Y+C A N+AGS
Sbjct: 322 ISNSSVVV---GG--VLIVQEAIIQDTGKYRCHASNIAGS 356



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPT-IQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
            ++ P     V  G+   F+  + + + P  I W R+G  I  T D    H     VL I 
Sbjct: 8    SIQPSPQQTVAGGETVVFRCAVNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIA 67

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            + ++ D+G + CRAT   G  E  A L VK++
Sbjct: 68   HAFDSDSGRYACRATNLLGTAEAIAVLNVKAE 99



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 1/116 (0%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PV     +  + +  G+   F C V     P   I W  +GQ I       T H      
Sbjct: 5    PVVSIQPSPQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNV 63

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLE 2224
            L I + +  DSG Y C+ATN LG A     L V     + +     + +   RQ+E
Sbjct: 64   LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVE 119



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 50/183 (27%), Positives = 70/183 (38%), Gaps = 18/183 (9%)

Query: 403 VTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           V  G+   F C V  G P P +TW  + + I +  ++       GN  L I +   SDSG
Sbjct: 17  VAGGETVVFRCAVNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGN-VLKIAHAFDSDSG 75

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
              C A N  G       LNV  + QV      + +    V  G  V L     G P P 
Sbjct: 76  RYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHY----VATGRQVELLCTVTGYPVPS 131

Query: 522 ITWQKDGVPIIPN-----PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           I W      I+PN     P L +    G   + I    +     Y+C A+N  G+     
Sbjct: 132 IEW------IVPNRTGLSPSL-VKVAQGVLKIVIENVTSPYEGRYRCMAKNNLGTAEEVV 184

Query: 577 RLY 579
           +L+
Sbjct: 185 QLF 187



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 19/133 (14%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+ + F C V     P   I W  + +P+ +     + H      L I H ++ DSG Y 
Sbjct: 20   GETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYA 78

Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSV--PD 2905
            C+ATN  G+A     L    +  +               V  + +  +A GR+  +    
Sbjct: 79   CRATNLLGTAEAIAVLNVKAEPQV--------------TVSPSRQHYVATGRQVELLCTV 124

Query: 2906 TEYPKP--EWIIP 2916
            T YP P  EWI+P
Sbjct: 125  TGYPVPSIEWIVP 137



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 4/120 (3%)

Query: 3978 QIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGW 4037
            Q   Q ++   ET  F C +   G P   + W  +G+P+ +    +  +      +    
Sbjct: 10   QPSPQQTVAGGETVVFRCAVN-AGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAH 68

Query: 4038 VYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVT 4097
             +  DSG Y CRATNL G  E  AV+    +P +      P     +   R++E    VT
Sbjct: 69   AFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVS---PSRQHYVATGRQVELLCTVT 125



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 31/103 (30%), Positives = 46/103 (44%), Gaps = 1/103 (0%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G++  F C V     P   I W  +GQP+ ++    T       VL IA+  + DSG Y 
Sbjct: 20   GETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYA 78

Query: 3224 CRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESL 3266
            CRA N  G     A +N   +  V +   +   +A  R++E L
Sbjct: 79   CRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVELL 121



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 1/114 (0%)

Query: 1712 VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALN 1771
            V   P     VA  +   F    +  G P   + W R+G PI  +   +T H      L 
Sbjct: 7    VSIQPSPQQTVAGGETVVFRCA-VNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLK 65

Query: 1772 MKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLE 1825
            + +    DSG Y CRA N LG A   + L V+++  + +    +  +   +Q+E
Sbjct: 66   IAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVE 119



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 40/150 (26%), Positives = 58/150 (38%), Gaps = 9/150 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W  +G+ I  +    T +     VL+I     +DSG Y+CRATN  G AE    L   
Sbjct: 38   ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVL--- 94

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
              +   +P+ T        +  G+     CTV     P   IEW    +     + +K  
Sbjct: 95   --NVKAEPQVTVSPSRQHYVATGRQVELLCTVTGYPVP--SIEWIVPNRTGLSPSLVKVA 150

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
               G + + I    +   G Y C A N  G
Sbjct: 151  Q--GVLKIVIENVTSPYEGRYRCMAKNNLG 178



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 24/89 (26%), Positives = 39/89 (43%)

Query: 290 SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
           +G P P +TW ++GQ + N+  +          L++ +   SDSG Y   A N  G    
Sbjct: 31  AGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEA 90

Query: 350 SGYLAVESPTESYVQDQRSQYITDTQQRE 378
              L V++  +  V   R  Y+   +Q E
Sbjct: 91  IAVLNVKAEPQVTVSPSRQHYVATGRQVE 119



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 3/107 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           P   I P    T   G  + F   +   G P   I W ++GQ I  +   ++        
Sbjct: 5   PVVSIQPSPQQTVAGGETVVFRCAVN-AGMPPPFITWSRDGQPINNTQDNSTAHVIEGNV 63

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV--TPRATIERTSQH 740
           L +      DSG Y CRA +  G AE  AVL+V   P+ T+  + QH
Sbjct: 64  LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQH 110



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 5/117 (4%)

Query: 1178 VFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVAL 1237
            V +QP S    V+ G+ +   C +   G P   + W  +G+ +       T +      L
Sbjct: 7    VSIQP-SPQQTVAGGETVVFRCAVNA-GMPPPFITWSRDGQPINNTQDNSTAHVIEGNVL 64

Query: 1238 DIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAI---EQIQLL 1291
             I HA  +D+G Y  RA N LG+A   A++ V     +      +  +    Q++LL
Sbjct: 65   KIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVELL 121



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 1/101 (0%)

Query: 1449 RPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIID 1508
            +P   + V  G+ V F C +         + W ++GQP+         H      L I  
Sbjct: 10   QPSPQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNVLKIAH 68

Query: 1509 LIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNE 1549
                DSG Y CRA NL+GT E    L  ++   +  S   +
Sbjct: 69   AFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQ 109



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 13/160 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     IEW    +T  +   ++   A G++ + I    +   G Y C A N  G AE 
Sbjct: 125  TGYPVPSIEWIVPNRTGLSPSLVKV--AQGVLKIVIENVTSPYEGRYRCMAKNNLGTAEE 182

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNI-EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
             V+L  V      +P     +Q + + +  G +A F CT   V  P  ++ W   G  M 
Sbjct: 183  VVQLFVVPNV--TRPN-NVSVQPVNQKVVKGNTATFNCTASGVPTP--QLVWERLGAKMP 237

Query: 3194 HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             +      SD G  +L I      DSGEY C A N  G +
Sbjct: 238  ETA---MTSDKG--LLTIESVGADDSGEYECIATNSEGSE 272



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 5/103 (4%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P  ++ +P N K+ +G  A F    SG P P++ W + G ++      E   T +   L 
Sbjct: 195 PNNVSVQPVNQKVVKGNTATFNCTASGVPTPQLVWERLGAKM-----PETAMTSDKGLLT 249

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
           + +    DSG Y  +A N  G       L V  P +  V  Q+
Sbjct: 250 IESVGADDSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQQ 292



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 1/101 (0%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P  +++      V  G  V F C V   G P   I W  +G+P        T +      
Sbjct: 5    PVVSIQPSPQQTVAGGETVVFRCAVN-AGMPPPFITWSRDGQPINNTQDNSTAHVIEGNV 63

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795
            L I + +  D+G Y CRATN  G+A   A +   A+  + +
Sbjct: 64   LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTV 104



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 6/104 (5%)

Query: 3824 PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            P+VS  P         TV   E V F C V     P   I W R+G+ + +     T + 
Sbjct: 5    PVVSIQPS-----PQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHV 58

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
            +    L I + +  DSG Y CRA N  G     A ++ K  P +
Sbjct: 59   IEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQV 102



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G+T  F C  +  G P   + W R+ + I ++   +  H      + I+H  D D G Y 
Sbjct: 20   GETVVFRCA-VNAGMPPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYA 78

Query: 2451 CRASNLLG 2458
            CRA+NLLG
Sbjct: 79   CRATNLLG 86



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P   + W +DG+PI  +   ++        L I H    D+G Y  RA N LG A + A 
Sbjct: 34  PPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAV 93

Query: 860 IRVAARSTVTADLGIPEQRRYI 881
           + V A   VT     P ++ Y+
Sbjct: 94  LNVKAEPQVTVS---PSRQHYV 112



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 20/80 (25%), Positives = 35/80 (43%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            + W  +G+P+       T +     +L+I   +  D+G Y C+ATN  G A     L VK
Sbjct: 38   ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVK 97

Query: 3651 GRQGIILEPQLPSHFKSGTE 3670
                + + P    +  +G +
Sbjct: 98   AEPQVTVSPSRQHYVATGRQ 117



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 9/75 (12%)

Query: 80  NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGP 138
           N +  +G  A F     G PTP + W R  A + E           T D  LL I+ +G 
Sbjct: 204 NQKVVKGNTATFNCTASGVPTPQLVWERLGAKMPE--------TAMTSDKGLLTIESVGA 255

Query: 139 GDEGEYTCTARNQYG 153
            D GEY C A N  G
Sbjct: 256 DDSGEYECIATNSEG 270



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG--EAVTT 2064
            P   + W  +G+P+       T +      L I +A+  D+G Y C+ATN +G  EA+  
Sbjct: 34   PPPFITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAV 93

Query: 2065 SSVKVD 2070
             +VK +
Sbjct: 94   LNVKAE 99



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 7/95 (7%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            N  V +G    F+C     G PT ++ W   G   A        +D G   L I+ + A 
Sbjct: 204  NQKVVKGNTATFNCTAS--GVPTPQLVWERLG---AKMPETAMTSDKGL--LTIESVGAD 256

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
            D+GEY C ATN  GS    AK+      D+ +  Q
Sbjct: 257  DSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQ 291



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G++  + C +     P   + W  +G+ + +     T++      L I   +  DSG Y 
Sbjct: 20   GETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYA 78

Query: 1919 CKAINNLGQAVSSIRLNVQSKESI 1942
            C+A N LG A +   LNV+++  +
Sbjct: 79   CRATNLLGTAEAIAVLNVKAEPQV 102



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 20/62 (32%), Positives = 29/62 (46%)

Query: 1344 VEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            + W  +G+PI        A+  +   L +   +  DSG Y C+ATN LG A     L V 
Sbjct: 38   ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVK 97

Query: 1404 AK 1405
            A+
Sbjct: 98   AE 99



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 9/98 (9%)

Query: 3277 PSAEPPKFITQIQDVT-KLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH 3335
            P+   P  ++ +Q V  K+V+G +A F      V  P L   W   G K+P         
Sbjct: 190  PNVTRPNNVS-VQPVNQKVVKGNTATFNCTASGVPTPQLV--WERLGAKMPET---AMTS 243

Query: 3336 DFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLK 3373
            D G++ ++ +    ++SGEYEC+ATN  G +   A L+
Sbjct: 244  DKGLLTIESVGA--DDSGEYECIATNSEGSERVLAKLE 279



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 7/109 (6%)

Query: 3824 PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            P V+ P     Q  +  V +     F C       P+L   W R G  +P         D
Sbjct: 190  PNVTRPNNVSVQPVNQKVVKGNTATFNCTASGVPTPQL--VWERLGAKMPET---AMTSD 244

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
             G ++++   V A+DSGEY C A N  G +   A +     PD+ +  Q
Sbjct: 245  KGLLTIES--VGADDSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQ 291



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 9/103 (8%)

Query: 2356 LESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRN 2415
            L +AE   +  +   VTR   V  QP+     + +G TA F+C     G PT ++ W   
Sbjct: 177  LGTAEEVVQLFVVPNVTRPNNVSVQPVNQ--KVVKGNTATFNCTAS--GVPTPQLVW--- 229

Query: 2416 EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            E+L         T D G   +TI  V  +D G Y C A+N  G
Sbjct: 230  ERLGAKMPETAMTSDKGL--LTIESVGADDSGEYECIATNSEG 270



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 35/165 (21%), Positives = 67/165 (40%), Gaps = 5/165 (3%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            PV ++  S  + +  GE   F   +     P   + W  +G+ +       T       +
Sbjct: 5    PVVSIQPSPQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNV 63

Query: 3480 LEISPTYPEDSGEYLCRAYNNYG--EAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAA 3537
            L+I+  +  DSG Y CRA N  G  EA+   ++K + +  +    Q        ++ +  
Sbjct: 64   LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAEPQVTVSPSRQHYVATGRQVELLCT 123

Query: 3538 LEGYS-GTVDTLTPEAESGNPPEFTTTPSDL-ILSENSSAHFECR 3580
            + GY   +++ + P     +P         L I+ EN ++ +E R
Sbjct: 124  VTGYPVPSIEWIVPNRTGLSPSLVKVAQGVLKIVIENVTSPYEGR 168



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 18/65 (27%), Positives = 29/65 (44%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W +DG+P+  +   +T        L I      D+G Y CRA N +G A   A L + 
Sbjct: 38   ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVK 97

Query: 1003 TKKDI 1007
             +  +
Sbjct: 98   AEPQV 102



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 18/130 (13%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G++ +E +G    DSG Y C ATN  G   +  KLE +       P      Q +  +  
Sbjct: 246  GLLTIESVGAD--DSGEYECIATNSEGSERVLAKLEVI-----VPPDVAVSPQQV-SINL 297

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+     C    V +P + + W      + +S    +V   G +++  A  Q  D+G+Y 
Sbjct: 298  GRPFRLFC----VSNPPLPLTWSKVNGTISNS----SVVVGGVLIVQEAIIQ--DTGKYR 347

Query: 3224 CRAYNKYGED 3233
            C A N  G D
Sbjct: 348  CHASNIAGSD 357



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 3/96 (3%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P+ +        +  G+ V     V     P   I W ++G  +       +        
Sbjct: 5    PVVSIQPSPQQTVAGGETVVFRCAVNAGMPPPF-ITWSRDGQPINNTQDNSTAHVIEGNV 63

Query: 2702 LSINSLRNDDSGIYTCKATNLLG--EAVSTASIKIE 2735
            L I    + DSG Y C+ATNLLG  EA++  ++K E
Sbjct: 64   LKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVKAE 99



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 16/44 (36%), Positives = 22/44 (50%)

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQ 1012
            LTI+SV   D+G Y C A N+ G     A L ++   D+    Q
Sbjct: 248  LTIESVGADDSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQ 291



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 18/82 (21%), Positives = 33/82 (40%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            + W  + +P+ +    +  +      L I      DSG Y CRA N LG A    +  V 
Sbjct: 38   ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLGTAEAIAVLNVK 97

Query: 1671 SKKSIYLESQHEGALPRLNQLE 1692
            ++  + +    +  +    Q+E
Sbjct: 98   AEPQVTVSPSRQHYVATGRQVE 119



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 15/49 (30%), Positives = 25/49 (51%)

Query: 3316 VEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG 3364
            + W  +G+ + +     T H     +L I + ++ +SG Y C ATN LG
Sbjct: 38   ITWSRDGQPINNTQDNSTAHVIEGNVLKIAHAFDSDSGRYACRATNLLG 86



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 9/118 (7%)

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            V  ++ +  +++   V VQP++    V +G      C     G PT ++ W   G  +  
Sbjct: 183  VVQLFVVPNVTRPNNVSVQPVNQK--VVKGNTATFNCTAS--GVPTPQLVWERLGAKMPE 238

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280
             +      D G + ++ + A   D+GEY   A N  GS    A + VI   D+    Q
Sbjct: 239  TAMTS---DKGLLTIESVGAD--DSGEYECIATNSEGSERVLAKLEVIVPPDVAVSPQ 291


>SB_10606| Best HMM Match : I-set (HMM E-Value=0)
          Length = 872

 Score =  100 bits (239), Expect = 3e-20
 Identities = 107/399 (26%), Positives = 164/399 (41%), Gaps = 45/399 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT--AK 4493
            G P P I W REN  +   PD  I      S L    +   DSA +A   E+  G   A 
Sbjct: 365  GVPRPKIIWLRENEVVY--PDDVIELGCNGS-LRFHGIRTRDSAEYACYVESYLGMDMAF 421

Query: 4494 CSANLVVEEKRRQGR-----GGIVPPSFT-----LTAQNVNVTSGQLVRLDTKVTGTKPI 4543
             S N+V+  + R+ +        +P S T     + + NV V     +R+    TG    
Sbjct: 422  TSVNVVLSLEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP 481

Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
             V W +NG  +    R ++   DG  T+LI  A   D+G + C A N AG+ +  +  +V
Sbjct: 482  RVTWRQNGNAISQGGRYRVTA-DGV-TMLIDGAVVSDTGSFTCEAENFAGKDKATSAVIV 539

Query: 4604 SLPA-----TKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWY 4657
             +PA       +KP+P +    +P  I   + D I A     + F C   G P+P+V W 
Sbjct: 540  KIPAKPSIERTNKPRPISPEDGSP--ITITIGDNITALTNTQVTFRCNATGTPMPSVIWT 597

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL------- 4710
            K  +++       +++   + ++ I +A P D G Y C A NS G   V++ L       
Sbjct: 598  KDGQVLVSGPRHVINK---DGSIVIQKASPVDRGRYTCTARNSHGEDRVSSTLNTMDPVV 654

Query: 4711 -KVTQPDQADNLPALTPLR-------DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
             K+  PD    +      R       +I             +T    PTI W R G  +P
Sbjct: 655  PKILSPDDPRTIHPDHRSRVHGTIGDNITALTDTLVTLHCPVTGVPAPTITWSRNGQEMP 714

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
               D  ++   NN  L++      D G +TC A  A G+
Sbjct: 715  ANGDGYLV--TNNGSLILEKVSSSDIGRYTCTARNAFGK 751



 Score = 86.6 bits (205), Expect = 4e-16
 Identities = 80/304 (26%), Positives = 128/304 (42%), Gaps = 43/304 (14%)

Query: 285 FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPN 344
           F+   +G P P V W K+GQ L++  +H I   +   ++ ++     D G YT  A N +
Sbjct: 582 FRCNATGTPMPSVIWTKDGQVLVSGPRHVI---NKDGSIVIQKASPVDRGRYTCTARNSH 638

Query: 345 GCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVT 404
           G    S  L    P    +         D +    + R  +         +    D  VT
Sbjct: 639 GEDRVSSTLNTMDPVVPKILSP-----DDPRTIHPDHRSRVH--GTIGDNITALTDTLVT 691

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
                   C VTG P P +TW  N +++  + +  ++ N   N +L++  V+ SD G  T
Sbjct: 692 ------LHCPVTGVPAPTITWSRNGQEMPANGDGYLVTN---NGSLILEKVSSSDIGRYT 742

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFV--ERFSTLNVREGEP--------------- 507
           C ARN  G+      +NV++    V+P+ V  +   T+   +G P               
Sbjct: 743 CTARNAFGKDNANSTVNVMDP---VSPEIVRSDEPRTIPPGDGSPLTATVGDNITALTNT 799

Query: 508 -VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            V L  +A GTP P + W KDG  ++  P   I+ +G   ++ I +A   D   Y CTA+
Sbjct: 800 QVTLRCQATGTPMPSVIWSKDGQVLVSGPRHVINKNG---SIVIQKASPVDRGRYTCTAR 856

Query: 567 NVAG 570
           N  G
Sbjct: 857 NSHG 860



 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 98/403 (24%), Positives = 157/403 (38%), Gaps = 41/403 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P PL+ W +   PI +    ++    T S++I+      DS  +   A N  G     
Sbjct: 256  GSPKPLVDWSKTGQPIISGD--RVSVTVTGSLVIVNSRS-SDSGEYVCTARNLLGEDSAV 312

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQN-VNVTSGQLVRL--DTKVTGTKPID------VY 4546
            + + +    R G          L   + VNVT+GQ V +  DT    + PI       + 
Sbjct: 313  STVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKGVPRPKII 372

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGE--ARCDAECVVS 4604
            WL+  + V PD    ++E     +L       +DS +Y C   +  G   A      V+S
Sbjct: 373  WLRENEVVYPD---DVIELGCNGSLRFHGIRTRDSAEYACYVESYLGMDMAFTSVNVVLS 429

Query: 4605 LPATKDK---PKPQTKAANAPPEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
            L   K K   P P T   +  P +   + D + V E   I   C   G P P V W +  
Sbjct: 430  LEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNG 489

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR--------VTVAAKLKV 4712
              I     +++  TAD  T+ I  A   D G + C A N AG+        V + AK  +
Sbjct: 490  NAISQGGRYRV--TADGVTMLIDGAVVSDTGSFTCEAENFAGKDKATSAVIVKIPAKPSI 547

Query: 4713 TQPDQA------DNLPALTPLRD-IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETP 4765
             + ++       D  P    + D I         F+   T    P++ W ++G ++   P
Sbjct: 548  ERTNKPRPISPEDGSPITITIGDNITALTNTQVTFRCNATGTPMPSVIWTKDGQVLVSGP 607

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
               +  +G+   ++I      D G +TC A  + G+   S+ L
Sbjct: 608  RHVINKDGS---IVIQKASPVDRGRYTCTARNSHGEDRVSSTL 647



 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 94/411 (22%), Positives = 165/411 (40%), Gaps = 43/411 (10%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E    R      G P P + W +    I     +++ T    ++LI   V V D+  F
Sbjct: 463  VLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRV-TADGVTMLIDGAV-VSDTGSF 520

Query: 4482 AAVAENRGGTAKCSANLVVE-----EKRRQGRGGIVPPS----FTLT-AQNVNVTSGQLV 4531
               AEN  G  K ++ ++V+        R  +   + P      T+T   N+   +   V
Sbjct: 521  TCEAENFAGKDKATSAVIVKIPAKPSIERTNKPRPISPEDGSPITITIGDNITALTNTQV 580

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
                  TGT    V W K+G+ +    R+ ++ +DG+  ++I +A P D G+Y C A NS
Sbjct: 581  TFRCNATGTPMPSVIWTKDGQVLVSGPRH-VINKDGS--IVIQKASPVDRGRYTCTARNS 637

Query: 4592 AGEARCDAECVVS---LPATKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIV 4647
             GE R  +        +P       P+T   +    +   + D I A     +   C + 
Sbjct: 638  HGEDRVSSTLNTMDPVVPKILSPDDPRTIHPDHRSRVHGTIGDNITALTDTLVTLHCPVT 697

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P PT+ W + G ++      + ++        ++S +   D G Y C A N+ G+   
Sbjct: 698  GVPAPTITWSRNGQEMPANGDGYLVTNNGSLILEKVSSS---DIGRYTCTARNAFGKDNA 754

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQP----------AQFKTQITSKIK------P 4750
             + + V  P   + + +  P R I   +G P          A   TQ+T + +      P
Sbjct: 755  NSTVNVMDPVSPEIVRSDEP-RTIPPGDGSPLTATVGDNITALTNTQVTLRCQATGTPMP 813

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
            ++ W ++G ++   P   +     N  ++I      D G +TC A  + G+
Sbjct: 814  SVIWSKDGQVLVSGPRHVI---NKNGSIVIQKASPVDRGRYTCTARNSHGE 861



 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 74/312 (23%), Positives = 132/312 (42%), Gaps = 36/312 (11%)

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
           N  + E +  +     +G P PRVTW +NG  +    ++ +  T +  T+ +     SD+
Sbjct: 460 NVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRV--TADGVTMLIDGAVVSDT 517

Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393
           G +T  AEN  G    +  + V+ P +  ++              T +   IS +  +P 
Sbjct: 518 GSFTCEAENFAGKDKATSAVIVKIPAKPSIE-------------RTNKPRPISPEDGSPI 564

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            + +  +          F C  TG P P V W  + + +     H  ++N+ G  +++I 
Sbjct: 565 TITIGDNITALTNTQVTFRCNATGTPMPSVIWTKDGQVLVSGPRH--VINKDG--SIVIQ 620

Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIEK--EQVVAPK-----FVERFSTLNVREGE 506
             +  D G  TC ARN  GE      LN ++    ++++P        +  S ++   G+
Sbjct: 621 KASPVDRGRYTCTARNSHGEDRVSSTLNTMDPVVPKILSPDDPRTIHPDHRSRVHGTIGD 680

Query: 507 P--------VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
                    V L+    G P P ITW ++G  +  N +  + T+ G+  L+  +  +SD 
Sbjct: 681 NITALTDTLVTLHCPVTGVPAPTITWSRNGQEMPANGDGYLVTNNGSLILE--KVSSSDI 738

Query: 559 AWYQCTAQNVAG 570
             Y CTA+N  G
Sbjct: 739 GRYTCTARNAFG 750



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 77/307 (25%), Positives = 124/307 (40%), Gaps = 48/307 (15%)

Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
           EG     +  + G P P +TW   G+ L  SN + I+         + NT+ SD+G Y  
Sbjct: 34  EGTSVSIKCPVQGIPAPAITWSNGGRFLPVSNGNSILV--------LSNTRVSDTGEYMC 85

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQ-RSQYITDTQQRETEERIEISEKALAPQFVKV 397
            A +P G    S  L V +P +  +      + I  T+ +     I  S  A        
Sbjct: 86  TAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTKAVSVNIRDSVTAFL------ 139

Query: 398 CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457
                   G   R  C   G P PEV W  + +++  D      V+E+G  ++++   T 
Sbjct: 140 --------GSTLRIRCSANGLPAPEVKWSKDGQRVVKD------VDENGTLSIVLRRTT- 184

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKE--QVVAPKFV------------ERFSTLNVR 503
            D+G   C A N  G    +  + V+E    ++VA K +            +   T+   
Sbjct: 185 -DAGRYVCTAVNAIGSDEAETFVYVVEPNYPRIVAKKGLATALDGRRPIAGQIGMTIRTL 243

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
               + L     G+P P + W K G PII    + +   G   +L I  +++SD+  Y C
Sbjct: 244 TSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTVTG---SLVIVNSRSSDSGEYVC 300

Query: 564 TAQNVAG 570
           TA+N+ G
Sbjct: 301 TARNLLG 307



 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 73/345 (21%), Positives = 133/345 (38%), Gaps = 23/345 (6%)

Query: 4381 KITSTETTEIEHKAQTQERVVEGPVKPSK-PPIFTKKMQPCRVFEHEQARFEVEFDGEPL 4439
            K TS    +I  K   +      P+ P    PI            + Q  F     G P+
Sbjct: 532  KATSAVIVKIPAKPSIERTNKPRPISPEDGSPITITIGDNITALTNTQVTFRCNATGTPM 591

Query: 4440 PLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANL- 4498
            P + W ++   + + P    H  +    ++I++    D   +   A N  G  + S+ L 
Sbjct: 592  PSVIWTKDGQVLVSGPR---HVINKDGSIVIQKASPVDRGRYTCTARNSHGEDRVSSTLN 648

Query: 4499 ----VVEEKRRQGRGGIVPPSFT-----LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549
                VV +         + P            N+   +  LV L   VTG     + W +
Sbjct: 649  TMDPVVPKILSPDDPRTIHPDHRSRVHGTIGDNITALTDTLVTLHCPVTGVPAPTITWSR 708

Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
            NG+++  +    ++  +G+  L++ +    D G+Y C A N+ G+   ++   V  P + 
Sbjct: 709  NGQEMPANGDGYLVTNNGS--LILEKVSSSDIGRYTCTARNAFGKDNANSTVNVMDPVSP 766

Query: 4610 D---KPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKP 4665
            +     +P+T        +   + D I A     +   C+  G P+P+V W K  +++  
Sbjct: 767  EIVRSDEPRTIPPGDGSPLTATVGDNITALTNTQVTLRCQATGTPMPSVIWSKDGQVLVS 826

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
                 +++     ++ I +A P D G Y C A NS G   V + L
Sbjct: 827  GPRHVINKNG---SIVIQKASPVDRGRYTCTARNSHGEDRVLSTL 868



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 126/502 (25%), Positives = 191/502 (38%), Gaps = 84/502 (16%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P  T+ +S  +N+   E++        T  P  +V W  NG ++  G R+R   D G  +
Sbjct: 451  PRVTIVIS--DNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTAD-GVTM 507

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            L I      D+G + C A N  G+   T+++ V                     KI A  
Sbjct: 508  L-IDGAVVSDTGSFTCEAENFAGKDKATSAVIV---------------------KIPAKP 545

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILS-ENSSAHFECRLIPVNDSSMRVEWFHNGK 3598
                T        E G+P   T T  D I +  N+   F C        S  V W  +G+
Sbjct: 546  SIERTNKPRPISPEDGSP--ITITIGDNITALTNTQVTFRCNATGTPMPS--VIWTKDGQ 601

Query: 3599 PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILE 3658
             L++G R   IN  G ++++      R  G YTC A N HGE  VS  L         ++
Sbjct: 602  VLVSGPR-HVINKDGSIVIQKASPVDR--GRYTCTARNSHGEDRVSSTLNT-------MD 651

Query: 3659 PQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCR 3718
            P +P              + L   +  TI  +  +  R    I DNI       V   C 
Sbjct: 652  PVVP--------------KILSPDDPRTIHPD--HRSRVHGTIGDNITALTDTLVTLHCP 695

Query: 3719 VEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
            V  V  PT  I W  NG+        + + + G  +L ++ + + D G YTC A N +G 
Sbjct: 696  VTGVPAPT--ITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGK 751

Query: 3779 ATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKS 3838
                + +        V++   P         E+ R   SD P+  P     P   T   +
Sbjct: 752  DNANSTVN-------VMDPVSP---------EIVR---SDEPRTIPPGDGSPLTATVGDN 792

Query: 3839 HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAED 3898
             T   +  V   C+      P   + W ++G++L SG R+  +   G  S+ I      D
Sbjct: 793  ITALTNTQVTLRCQATGTPMPS--VIWSKDGQVLVSGPRH-VINKNG--SIVIQKASPVD 847

Query: 3899 SGEYICRAVNDFGEDFTKATIS 3920
             G Y C A N  GED   +T++
Sbjct: 848  RGRYTCTARNSHGEDRVLSTLN 869



 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 100/422 (23%), Positives = 161/422 (38%), Gaps = 54/422 (12%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            + P+ T       V E      +    G P P I W        N   F +   +  SIL
Sbjct: 19   RKPVSTTIGSRVTVLEGTSVSIKCPVQGIPAPAITW-------SNGGRF-LPVSNGNSIL 70

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGG-IVPPSFTLT---AQNVN 4524
            ++    V D+  +   A +  G    S  L V   ++    G +V     LT   A +VN
Sbjct: 71   VLSNTRVSDTGEYMCTAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTKAVSVN 130

Query: 4525 VTS------GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP 4578
            +        G  +R+     G    +V W K+G++V  D+     +E+GT ++++     
Sbjct: 131  IRDSVTAFLGSTLRIRCSANGLPAPEVKWSKDGQRVVKDV-----DENGTLSIVLRRT-- 183

Query: 4579 QDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPP-EIIEPLKDKI---- 4633
             D+G+Y C A+N+ G    +    V  P   + P+   K   A   +   P+  +I    
Sbjct: 184  TDAGRYVCTAVNAIGSDEAETFVYVVEP---NYPRIVAKKGLATALDGRRPIAGQIGMTI 240

Query: 4634 -VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
                  +I   C + G P P V W K  + I       ++ T    +L I  +   D G+
Sbjct: 241  RTLTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTVTG---SLVIVNSRSSDSGE 297

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQA------DNLPALTPLRDIVVYEGQ----PAQFKT 4742
            Y C A N  G  +  + + +  P +        ++ AL     + V  GQ    PA   T
Sbjct: 298  YVCTARNLLGEDSAVSTVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTST 357

Query: 4743 QITSKIK----PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
             I+  IK    P I WLRE  ++   PD  +I  G N  L        D+  + C   + 
Sbjct: 358  VISCPIKGVPRPKIIWLRENEVV--YPD-DVIELGCNGSLRFHGIRTRDSAEYACYVESY 414

Query: 4799 AG 4800
             G
Sbjct: 415  LG 416



 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 161/715 (22%), Positives = 259/715 (36%), Gaps = 121/715 (16%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG    +++W   G+ I +  R+ +V   G +V  I+ ++++DSG Y C A N  G+   
Sbjct: 255  TGSPKPLVDWSKTGQPIISGDRV-SVTVTGSLV--IVNSRSSDSGEYVCTARNLLGEDSA 311

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD-----------PDMKI 3183
               +  ++  +        HI  + G         +   VP D            P  KI
Sbjct: 312  VSTVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKGVPRPKI 371

Query: 3184 EWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
             W    + +     I+   +       I   +  DS EY C   +  G D    ++N   
Sbjct: 372  IWLRENEVVYPDDVIELGCNGSLRFHGI---RTRDSAEYACYVESYLGMDMAFTSVNVV- 427

Query: 3244 KGGVYLESLQPDSLAKIRELESLQGAQQQTPST-PSAEPPKFITQIQDVTKLVEGQSAHF 3302
               + LE  +P  LA              +P T P +  P+    I D   ++E  +   
Sbjct: 428  ---LSLEPRKPKILAP-------------SPLTIPLSGTPRVTIVISDNVTVLEDSTIRI 471

Query: 3303 EARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNK 3362
                  +  P  +V W  NG  +  G RYR   D G+ +L I      ++G + C A N 
Sbjct: 472  VCNATGLPAP--RVTWRQNGNAISQGGRYRVTAD-GVTML-IDGAVVSDTGSFTCEAENF 527

Query: 3363 LGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVF 3422
             G+D      K TS   +I+  ++P   +  +E+           K   +  E G     
Sbjct: 528  AGKD------KATSA--VIV--KIP--AKPSIER---------TNKPRPISPEDGSPITI 566

Query: 3423 TVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI 3482
            T+     +N+    N     R   T  P   V W  +G+ L +G R     D   VI + 
Sbjct: 567  TIG----DNITALTNTQVTFRCNATGTPMPSVIWTKDGQVLVSGPRHVINKDGSIVIQKA 622

Query: 3483 SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYS 3542
            SP    D G Y C A N++GE   ++++                 M+  + KI + +   
Sbjct: 623  SPV---DRGRYTCTARNSHGEDRVSSTLNT---------------MDPVVPKILSPD--- 661

Query: 3543 GTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT 3602
                T+ P+  S       T   ++    ++     C +  V   +  + W  NG+ +  
Sbjct: 662  -DPRTIHPDHRS---RVHGTIGDNITALTDTLVTLHCPVTGV--PAPTITWSRNGQEMPA 715

Query: 3603 GSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLP 3662
                  + + G +ILE   V   D G YTC A N  G+   +  + V       ++P  P
Sbjct: 716  NGDGYLVTNNGSLILE--KVSSSDIGRYTCTARNAFGKDNANSTVNV-------MDPVSP 766

Query: 3663 SHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPV 3722
                          E +   E  TI     +P   T  + DNI       V   C  +  
Sbjct: 767  --------------EIVRSDEPRTIPPGDGSP--LTATVGDNITALTNTQVTLRC--QAT 808

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG 3777
            G P   + W  +G+   +G R H +N  G I   I      D G YTC A N  G
Sbjct: 809  GTPMPSVIWSKDGQVLVSGPR-HVINKNGSIV--IQKASPVDRGRYTCTARNSHG 860



 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 92/413 (22%), Positives = 153/413 (37%), Gaps = 46/413 (11%)

Query: 4429 RFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENR 4488
            R     +G P P +KW ++   +    D       T SI++ R     D+  +   A N 
Sbjct: 144  RIRCSANGLPAPEVKWSKDGQRVVKDVDEN----GTLSIVLRRTT---DAGRYVCTAVNA 196

Query: 4489 GGTAKCSANLVVEEK---RRQGRGGIVP------PSFTLTAQNVNVTSGQLVRLDTKVTG 4539
             G+ +    + V E    R   + G+        P        +   +   + L   VTG
Sbjct: 197  IGSDEAETFVYVVEPNYPRIVAKKGLATALDGRRPIAGQIGMTIRTLTSTSITLKCPVTG 256

Query: 4540 T-KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCD 4598
            + KP+ V W K G   QP I    +    T +L+I+ +   DSG+Y C A N  GE    
Sbjct: 257  SPKPL-VDWSKTG---QPIISGDRVSVTVTGSLVIVNSRSSDSGEYVCTARNLLGEDSAV 312

Query: 4599 AECVVSLPATKDKPKPQTKAANAP---PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
            +   +  P               P   P  +   +D  V    +   SC I G P P + 
Sbjct: 313  STVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKGVPRPKII 372

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR------VTVAAK 4709
            W + ++++ P    ++       +LR       D  +Y C   +  G       V V   
Sbjct: 373  WLRENEVVYPDDVIELGCNG---SLRFHGIRTRDSAEYACYVESYLGMDMAFTSVNVVLS 429

Query: 4710 LKVTQPDQADNLPALTPLR-----------DIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
            L+  +P      P   PL            ++ V E    +     T    P + W + G
Sbjct: 430  LEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNG 489

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              I +   +++  +G    +LI      DTG+FTC A   AG+ + ++ ++VK
Sbjct: 490  NAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGKDKATSAVIVK 540



 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 72/306 (23%), Positives = 120/306 (39%), Gaps = 37/306 (12%)

Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348
           + G PRP++ W +  + +      ++I    + +LR    +  DS  Y    E+  G  +
Sbjct: 363 IKGVPRPKIIWLRENEVVYPD---DVIELGCNGSLRFHGIRTRDSAEYACYVESYLG--M 417

Query: 349 TSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDR-DVTEGK 407
              + +V       ++ ++ + +  +        I +S     P+   V  D   V E  
Sbjct: 418 DMAFTSVNVVLS--LEPRKPKILAPSPLT-----IPLSG---TPRVTIVISDNVTVLEDS 467

Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467
             R  C  TG P P VTW  N   I     +++  +      ++I    +SD+G  TC A
Sbjct: 468 TIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTAD---GVTMLIDGAVVSDTGSFTCEA 524

Query: 468 RNKSGETAFQCRLNV-------IEKEQVVAPKFVERFSTLNVREGE--------PVVLNA 512
            N +G+      + V       IE+     P   E  S + +  G+         V    
Sbjct: 525 ENFAGKDKATSAVIVKIPAKPSIERTNKPRPISPEDGSPITITIGDNITALTNTQVTFRC 584

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
            A GTP P + W KDG  ++  P   I+ DG   ++ I +A   D   Y CTA+N  G  
Sbjct: 585 NATGTPMPSVIWTKDGQVLVSGPRHVINKDG---SIVIQKASPVDRGRYTCTARNSHGED 641

Query: 573 ATRARL 578
              + L
Sbjct: 642 RVSSTL 647



 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 115/490 (23%), Positives = 171/490 (34%), Gaps = 95/490 (19%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            PR T+ I DN+ V E   +   C     G P  R+ W  NG   + G R     D   + 
Sbjct: 451  PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYRVTADG--VT 506

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            + ID     D G +TC A N  G    T+ +       IV   ++P   S   I+   + 
Sbjct: 507  MLIDGAVVSDTGSFTCEAENFAGKDKATSAV-------IV---KIPAKPS---IERTNKP 553

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
            R        PI  T    IT + +  V       F C       P   + W ++G++L S
Sbjct: 554  RPISPEDGSPITITIGDNITALTNTQVT------FRCNATGTPMPS--VIWTKDGQVLVS 605

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVP 3934
            G R+    D   V   I      D G Y C A N  GED                     
Sbjct: 606  GPRHVINKDGSIV---IQKASPVDRGRYTCTARNSHGED--------------------- 641

Query: 3935 RGMKRSEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFE 3994
               + S  L  M+  + K      L+ DD   +      R    I    + +        
Sbjct: 642  ---RVSSTLNTMDPVVPKI-----LSPDDPRTIHPDHRSRVHGTIGDNITALTDTLVTLH 693

Query: 3995 CQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPE-----DSGEYLCR 4049
            C +  V  P   + W  NG+ +       P    GY+  N G +  E     D G Y C 
Sbjct: 694  CPVTGVPAPT--ITWSRNGQEM-------PANGDGYLVTNNGSLILEKVSSSDIGRYTCT 744

Query: 4050 ATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARC 4109
            A N +G D   + +        V D   P+ ++S E            P  +     +  
Sbjct: 745  ARNAFGKDNANSTVN-------VMDPVSPEIVRSDE------------PRTIPPGDGS-- 783

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDI 4169
             P+  ++ D +T          C+ TG P P V+W  +G  +V+G R+ +  +G     I
Sbjct: 784  -PLTATVGDNITALTNTQVTLRCQATGTPMPSVIWSKDGQVLVSGPRHVINKNG--SIVI 840

Query: 4170 PKTRQYDTGK 4179
             K    D G+
Sbjct: 841  QKASPVDRGR 850



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 174/723 (24%), Positives = 276/723 (38%), Gaps = 133/723 (18%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE-AVTSGIAIV 1669
            V+W    +P+ SG R + T     V ++  S    DSG Y C A N LGE +  S + I+
Sbjct: 262  VDWSKTGQPIISGDRVSVTVTGSLVIVNSRS---SDSGEYVCTARNLLGEDSAVSTVNIL 318

Query: 1670 HS-KKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAA 1728
            +  +  I+    H  ALP  + +  T+  Q  S   +  T   V + P+K          
Sbjct: 319  NPVRPGIFASYGHINALPGFSPVNVTAG-QDVSVPADTST---VISCPIK---------- 364

Query: 1729 HFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAI 1788
                     G P+ ++ WLR    +   + +  +   G  +L    +   DS  Y C   
Sbjct: 365  ---------GVPRPKIIWLRENEVVYPDD-VIELGCNG--SLRFHGIRTRDSAEYACYVE 412

Query: 1789 NELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFIT 1848
            + LG  +     F      L LE +    L                 + + ++  PR   
Sbjct: 413  SYLGMDMA----FTSVNVVLSLEPRKPKILAP-------------SPLTIPLSGTPRVTI 455

Query: 1849 QLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILT 1908
             ++    + E  +    C     P P  RV W  NG  +  G RYR + D     +D   
Sbjct: 456  VISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTADGVTMLIDGAV 513

Query: 1909 VYGEDSGEYTCKAINNLG--QAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKR 1966
            V   D+G +TC+A N  G  +A S++ + + +K SI R ++           ED S    
Sbjct: 514  V--SDTGSFTCEAENFAGKDKATSAVIVKIPAKPSIERTNKPRPISP-----EDGSPITI 566

Query: 1967 AVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRF 2026
             + D+            + N +VT        AT TP+  P+  V W  +G+ +  G R 
Sbjct: 567  TIGDNI---------TALTNTQVT----FRCNATGTPM--PS--VIWTKDGQVLVSGPRH 609

Query: 2027 KTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLK 2086
                D   V   I  A   D G Y C A N+ GE   +S+          L+T+D     
Sbjct: 610  VINKDGSIV---IQKASPVDRGRYTCTARNSHGEDRVSST----------LNTMD----P 652

Query: 2087 KIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWF 2146
             + ++   + P+ I  +   +  V  T   ++  L +       C V  +  P  TI W 
Sbjct: 653  VVPKILSPDDPRTIHPDHRSR--VHGTIGDNITALTD-TLVTLHCPVTGVPAP--TITWS 707

Query: 2147 HNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR 2205
             NGQ++ A G  Y  T++ G + L+     + D G Y C A N  G+           + 
Sbjct: 708  RNGQEMPANGDGYLVTNN-GSLILE--KVSSSDIGRYTCTARNAFGK----------DNA 754

Query: 2206 NIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQ 2265
            N  ++   P   E +R             +EP+  PP   + L  T  V +  TA    Q
Sbjct: 755  NSTVNVMDPVSPEIVRS------------DEPRTIPPGDGSPLTAT--VGDNITALTNTQ 800

Query: 2266 V----EPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAIN 2321
            V    +    P   + +  +G+ L S  R H+    G  S+ IQ   P D G Y+  A N
Sbjct: 801  VTLRCQATGTPMPSVIWSKDGQVLVSGPR-HVINKNG--SIVIQKASPVDRGRYTCTARN 857

Query: 2322 ALG 2324
            + G
Sbjct: 858  SHG 860



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 105/445 (23%), Positives = 173/445 (38%), Gaps = 68/445 (15%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG-EAFTSS 2999
            P  ++ W  NG  + QG R+++T+D   VT+ +      D+G +TC+A N  G +  TS+
Sbjct: 479  PAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGAVVSDTGSFTCEAENFAGKDKATSA 536

Query: 3000 TVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVD 3059
             +        IERT  P+                      P+D +   P   T+  +I  
Sbjct: 537  VIVKIPAKPSIERTNKPRPI-------------------SPEDGS---PITITIGDNITA 574

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            ++  Q+  +  +   TG     + W  +G+ + +  R   +   G +V++       D G
Sbjct: 575  LTNTQVT-FRCN--ATGTPMPSVIWTKDGQVLVSGPR-HVINKDGSIVIQ--KASPVDRG 628

Query: 3120 TYSCRATNKWGQAEISVKLECVDK-----SKGQKPR--FTTHIQNIEG-LKDGQSAHFEC 3171
             Y+C A N  G+  +S  L  +D           PR     H   + G + D  +A  + 
Sbjct: 629  RYTCTARNSHGEDRVSSTLNTMDPVVPKILSPDDPRTIHPDHRSRVHGTIGDNITALTDT 688

Query: 3172 TVV---PVDD-PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             V    PV   P   I W  NGQ M  +     V++ G ++L+     + D G Y C A 
Sbjct: 689  LVTLHCPVTGVPAPTITWSRNGQEMPANGDGYLVTNNGSLILE--KVSSSDIGRYTCTAR 746

Query: 3228 NKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQ 3287
            N +G+D   +T+N        ++ + P         E ++  + +T   P    P   T 
Sbjct: 747  NAFGKDNANSTVN-------VMDPVSP---------EIVRSDEPRT-IPPGDGSPLTATV 789

Query: 3288 IQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYC 3347
              ++T L   Q      R      P   V W  +G+ L  G R+    +  IVI      
Sbjct: 790  GDNITALTNTQ---VTLRCQATGTPMPSVIWSKDGQVLVSGPRHVINKNGSIVIQK---A 843

Query: 3348 YEENSGEYECVATNKLGRDSTKANL 3372
               + G Y C A N  G D   + L
Sbjct: 844  SPVDRGRYTCTARNSHGEDRVLSTL 868



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 71/305 (23%), Positives = 124/305 (40%), Gaps = 42/305 (13%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
           G+  + +   +G P P V W K+GQR++            + TL +   + +D+G Y   
Sbjct: 140 GSTLRIRCSANGLPAPEVKWSKDGQRVVKD-------VDENGTLSIVLRRTTDAGRYVCT 192

Query: 340 AENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ 399
           A N  G      ++ V  P    +  ++        +R    +I ++ + L         
Sbjct: 193 AVNAIGSDEAETFVYVVEPNYPRIVAKKGLATALDGRRPIAGQIGMTIRTL--------- 243

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
               T   +T   C VTG P P V W    + I      ++ V  +G+  L+I N   SD
Sbjct: 244 ----TSTSIT-LKCPVTGSPKPLVDWSKTGQPIIS--GDRVSVTVTGS--LVIVNSRSSD 294

Query: 460 SGVVTCVARNKSGETAFQCRLNVIE--KEQVVAP----KFVERFSTLNVREGEPV----- 508
           SG   C ARN  GE +    +N++   +  + A       +  FS +NV  G+ V     
Sbjct: 295 SGEYVCTARNLLGEDSAVSTVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPAD 354

Query: 509 ---VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
              V++    G P P+I W ++   + P+  + +  +G   +L     +  D+A Y C  
Sbjct: 355 TSTVISCPIKGVPRPKIIWLRENEVVYPDDVIELGCNG---SLRFHGIRTRDSAEYACYV 411

Query: 566 QNVAG 570
           ++  G
Sbjct: 412 ESYLG 416



 Score = 62.5 bits (145), Expect = 8e-09
 Identities = 53/192 (27%), Positives = 80/192 (41%), Gaps = 31/192 (16%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V EG      C V G P P +TW    R          L   +GN  L+++N  +SD+G 
Sbjct: 32  VLEGTSVSIKCPVQGIPAPAITWSNGGR---------FLPVSNGNSILVLSNTRVSDTGE 82

Query: 463 VTCVARNKSGETAFQCRLNVI--EKEQV-------VAPKFVERFSTLNVRE------GEP 507
             C A +  G  A    L V+  +K  +       V P    +  ++N+R+      G  
Sbjct: 83  YMCTAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTKAVSVNIRDSVTAFLGST 142

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           + +   A G P P + W KDG  ++ +    +  +G   TL I   + +DA  Y CTA N
Sbjct: 143 LRIRCSANGLPAPEVKWSKDGQRVVKD----VDENG---TLSIVLRRTTDAGRYVCTAVN 195

Query: 568 VAGSTATRARLY 579
             GS      +Y
Sbjct: 196 AIGSDEAETFVY 207



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 117/472 (24%), Positives = 177/472 (37%), Gaps = 77/472 (16%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P  T V  D V + E        +   TG  +  + W  NG  I    R R V A G+ +
Sbjct: 451  PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYR-VTADGVTM 507

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQ----AEISVKLECVDK-SKGQKPR---------FTT 3153
            L I G   +D+G+++C A N  G+    + + VK+       +  KPR          T 
Sbjct: 508  L-IDGAVVSDTGSFTCEAENFAGKDKATSAVIVKIPAKPSIERTNKPRPISPEDGSPITI 566

Query: 3154 HI-QNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIA 3212
             I  NI  L + Q   F C       P   + W  +GQ +    R   ++  G +V+  A
Sbjct: 567  TIGDNITALTNTQVT-FRCNATGTPMPS--VIWTKDGQVLVSGPR-HVINKDGSIVIQKA 622

Query: 3213 YTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQ 3272
                 D G Y C A N +GED   +T+N      V  + L PD    I         + +
Sbjct: 623  SPV--DRGRYTCTARNSHGEDRVSSTLNTMDP--VVPKILSPDDPRTIH-----PDHRSR 673

Query: 3273 TPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLP-HGHRY 3331
               T        IT + D   LV   + H     VP       + W  NG+++P +G  Y
Sbjct: 674  VHGTIGDN----ITALTDT--LV---TLHCPVTGVPAP----TITWSRNGQEMPANGDGY 720

Query: 3332 RTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGME 3391
               ++ G +IL+ +     + G Y C A N  G+D+  + +        ++D   P    
Sbjct: 721  LVTNN-GSLILEKV--SSSDIGRYTCTARNAFGKDNANSTVN-------VMDPVSPE--- 767

Query: 3392 GGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPN 3451
                         + R D       G     T  +   +N+    N     R   T  P 
Sbjct: 768  -------------IVRSDEPRTIPPGDGSPLTATVG--DNITALTNTQVTLRCQATGTPM 812

Query: 3452 LKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGE 3503
              V W  +G+ L +G R     +   VI + SP    D G Y C A N++GE
Sbjct: 813  PSVIWSKDGQVLVSGPRHVINKNGSIVIQKASPV---DRGRYTCTARNSHGE 861



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 19/195 (9%)

Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348
           ++G P P +TW +NGQ +  +    ++T  N+ +L +     SD G YT  A N  G   
Sbjct: 696 VTGVPAPTITWSRNGQEMPANGDGYLVT--NNGSLILEKVSSSDIGRYTCTARNAFGKDN 753

Query: 349 TSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKM 408
            +  + V  P    +             R  E R  I     +P    V  +        
Sbjct: 754 ANSTVNVMDPVSPEIV------------RSDEPRT-IPPGDGSPLTATVGDNITALTNTQ 800

Query: 409 TRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
               C+ TG P P V W  + + +     H  ++N++G+  ++I   +  D G  TC AR
Sbjct: 801 VTLRCQATGTPMPSVIWSKDGQVLVSGPRH--VINKNGS--IVIQKASPVDRGRYTCTAR 856

Query: 469 NKSGETAFQCRLNVI 483
           N  GE      LN +
Sbjct: 857 NSHGEDRVLSTLNTM 871



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 113/479 (23%), Positives = 173/479 (36%), Gaps = 75/479 (15%)

Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242
            +S+   V E   I + C     G P  RV W  NG +++ G R++   D   V + I  A
Sbjct: 457  ISDNVTVLEDSTIRIVCNAT--GLPAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGA 512

Query: 1243 TSADTGEYTVRAVNHLG-SAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQV 1301
              +DTG +T  A N  G    TSA++  I     +  T   + I      ED +  T  +
Sbjct: 513  VVSDTGSFTCEAENFAGKDKATSAVIVKIPAKPSIERTNKPRPISP----EDGSPITITI 568

Query: 1302 REDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRP 1361
             ++IT +                 TN  +  R    G     V W  +G+ + +G R   
Sbjct: 569  GDNITAL-----------------TNTQVTFRCNATGTPMPSVIWTKDGQVLVSGPRHVI 611

Query: 1362 AYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKI 1421
              +   V   +    P D G YTC A N  GE   S  L  +    ++ +   P     I
Sbjct: 612  NKDGSIV---IQKASPVDRGRYTCTARNSHGEDRVSSTLNTM--DPVVPKILSPDDPRTI 666

Query: 1422 QYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF 1481
             + +  SR   T  I +++T               +    V   C +  V      + W 
Sbjct: 667  -HPDHRSRVHGT--IGDNIT--------------ALTDTLVTLHCPVTGVPAPT--ITWS 707

Query: 1482 KNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541
            +NGQ +        + + G + L+ +   + D G YTC A N  G D  +      ST +
Sbjct: 708  RNGQEMPANGDGYLVTNNGSLILEKVS--SSDIGRYTCTARNAFGKDNAN------STVN 759

Query: 1542 IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRL 1601
            ++     E       V  D  +         +T       T+L N ++    R       
Sbjct: 760  VMDPVSPEI------VRSDEPRTIPPGDGSPLTATVGDNITALTNTQVT--LRCQATGTP 811

Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            +P       V W  + + L SG R     N   V   I    P D G YTC A N+ GE
Sbjct: 812  MP------SVIWSKDGQVLVSGPRHVINKNGSIV---IQKASPVDRGRYTCTARNSHGE 861



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 14/144 (9%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQ---KPRFTTHIQN---IEG- 3160
            L I+  +TTD+G Y C A N  G  E    +  V+ +  +   K    T +     I G 
Sbjct: 176  LSIVLRRTTDAGRYVCTAVNAIGSDEAETFVYVVEPNYPRIVAKKGLATALDGRRPIAGQ 235

Query: 3161 ----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
                ++   S            P   ++W   GQP+    R+        V+++   +++
Sbjct: 236  IGMTIRTLTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTVTGSLVIVN---SRS 292

Query: 3217 HDSGEYVCRAYNKYGEDFTRATIN 3240
             DSGEYVC A N  GED   +T+N
Sbjct: 293  SDSGEYVCTARNLLGEDSAVSTVN 316



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 5/87 (5%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E   PI   I  N          F     G P P V WT+    LV   ++ +       
Sbjct: 559 EDGSPITITIGDNITALTNTQVTFRCNATGTPMPSVIWTKDGQVLVSGPRHVINK----- 613

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGE 154
           D S++I++  P D G YTCTARN +GE
Sbjct: 614 DGSIVIQKASPVDRGRYTCTARNSHGE 640



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 49/191 (25%), Positives = 76/191 (39%), Gaps = 25/191 (13%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            +V W  N   +  G R+  T +   + +D    +  D+G++TC A N  G+   +   IV
Sbjct: 482  RVTWRQNGNAISQGGRYRVTADGVTMLID--GAVVSDTGSFTCEAENFAGKDKATSAVIV 539

Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729
                           +P    +E T+K +  S +D     +P+      +I    N    
Sbjct: 540  --------------KIPAKPSIERTNKPRPISPED----GSPITITIGDNITALTNTQVT 581

Query: 1730 FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAIN 1789
            F  R    G P   V W ++G  + +  R     D   V   ++  +P D G YTC A N
Sbjct: 582  F--RCNATGTPMPSVIWTKDGQVLVSGPRHVINKDGSIV---IQKASPVDRGRYTCTARN 636

Query: 1790 ELGEAVTSSTL 1800
              GE   SSTL
Sbjct: 637  SHGEDRVSSTL 647



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 5/83 (6%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           PI  QI    R     +   +  + G+P P+V W++   P++  ++ S+     TG  SL
Sbjct: 231 PIAGQIGMTIRTLTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTV---TG--SL 285

Query: 132 LIKQIGPGDEGEYTCTARNQYGE 154
           +I      D GEY CTARN  GE
Sbjct: 286 VIVNSRSSDSGEYVCTARNLLGE 308



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 65/255 (25%), Positives = 100/255 (39%), Gaps = 38/255 (14%)

Query: 1976 EKPQFGKPIKNAEV----TEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQ------GHR 2025
            +KP    P+    +    T+   V++  ++T     T+R+    NG P  +      G R
Sbjct: 106  QKPSISGPVVGRVIPLTKTKAVSVNIRDSVTAFLGSTLRIRCSANGLPAPEVKWSKDGQR 165

Query: 2026 FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL 2085
                 D     L I+     D G Y+C A NA+G          +A++ +Y+   +  R+
Sbjct: 166  VVKDVDENGT-LSIVLRRTTDAGRYVCTAVNAIGSD--------EAETFVYVVEPNYPRI 216

Query: 2086 KKIQELEK-YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTID 2144
               + L    +  +PI     GQ  + +  LTS            +C V     P   +D
Sbjct: 217  VAKKGLATALDGRRPIA----GQIGMTIRTLTSTS-------ITLKCPVT--GSPKPLVD 263

Query: 2145 WFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE--AVNTCTLKVA 2202
            W   GQ I +G R   T     V   I+ + + DSG Y+C A N LGE  AV+T  +   
Sbjct: 264  WSKTGQPIISGDRVSVTVTGSLV---IVNSRSSDSGEYVCTARNLLGEDSAVSTVNILNP 320

Query: 2203 GHRNIILDTQHPNGL 2217
                I     H N L
Sbjct: 321  VRPGIFASYGHINAL 335



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 3816 ISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875
            ++ +P   P+  TP   I    + TV E   +R  C       P  R+ W +NG  +  G
Sbjct: 438  LAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQG 495

Query: 3876 HRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
             RYR   D   + +D   V   D+G + C A N  G+D   + +  K
Sbjct: 496  GRYRVTADGVTMLIDGAVV--SDTGSFTCEAENFAGKDKATSAVIVK 540



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 40/233 (17%)

Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704
           SVTA  G  +    R    G P  +++W K+GQ +        +   G +S+ +      
Sbjct: 134 SVTAFLGSTLRI--RCSANGLPAPEVKWSKDGQRV-----VKDVDENGTLSIVLRRTT-- 184

Query: 705 DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEE 764
           D+G Y C AV+A G                   S   ET  Y+ +  +Y +   ++ +  
Sbjct: 185 DAGRYVCTAVNAIG-------------------SDEAETFVYVVE-PNYPRIVAKKGLAT 224

Query: 765 QTSQRPQFIRPLQ-DLGELQEGRNAHFEAQLTPVS-DPTMRVEWYKDGRPITASSRITSI 822
               R    RP+   +G       +       PV+  P   V+W K G+PI +  R+ S+
Sbjct: 225 ALDGR----RPIAGQIGMTIRTLTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRV-SV 279

Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE--AISTASIRVAARSTVTADLG 873
              G  SL I++ R+ D+G Y   A N LGE  A+ST +I    R  + A  G
Sbjct: 280 TVTG--SLVIVNSRSSDSGEYVCTARNLLGEDSAVSTVNILNPVRPGIFASYG 330



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/63 (44%), Positives = 36/63 (57%), Gaps = 5/63 (7%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGE--AVST 2729
            P   ++W K G  + +G R+  T    LV   +NS R+ DSG Y C A NLLGE  AVST
Sbjct: 258  PKPLVDWSKTGQPIISGDRVSVTVTGSLVI--VNS-RSSDSGEYVCTARNLLGEDSAVST 314

Query: 2730 ASI 2732
             +I
Sbjct: 315  VNI 317



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQ 125
           PG+ SP +   +  N             +  G P P V W++    LV   ++ +  N  
Sbjct: 779 PGDGSP-LTATVGDNITALTNTQVTLRCQATGTPMPSVIWSKDGQVLVSGPRHVINKNG- 836

Query: 126 TGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
               S++I++  P D G YTCTARN +GE
Sbjct: 837 ----SIVIQKASPVDRGRYTCTARNSHGE 861



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 81/329 (24%), Positives = 123/329 (37%), Gaps = 48/329 (14%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595
            G P+ R  W  NG  +  G R+R T D   VT+ I+  V +D G + C+A N AG     
Sbjct: 477  GLPAPRVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAG----- 529

Query: 2596 XXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLV 2655
                      I+    +P S E+        NK   +  + G   +PI  T   +   L 
Sbjct: 530  --KDKATSAVIVKIPAKP-SIER-------TNKPRPISPEDG---SPITITIGDNITALT 576

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
              Q  +   +      P   + W K+G  L +G R     D  +V   I      D G Y
Sbjct: 577  NTQVTF---RCNATGTPMPSVIWTKDGQVLVSGPRHVINKDGSIV---IQKASPVDRGRY 630

Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXV 2775
            TC A N  GE   ++++   D   ++ + L PD    I                     V
Sbjct: 631  TCTARNSHGEDRVSSTLNTMDP--VVPKILSPDDPRTI--------------HPDHRSRV 674

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLD 2834
              +  +NI       +   C V     PT  I W  N + +P +G  Y  T++ S +   
Sbjct: 675  HGTIGDNITALTDTLVTLHCPVTGVPAPT--ITWSRNGQEMPANGDGYLVTNNGSLI--- 729

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            +      D G YTC A N+ G    + ++
Sbjct: 730  LEKVSSSDIGRYTCTARNAFGKDNANSTV 758



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 57/222 (25%), Positives = 86/222 (38%), Gaps = 34/222 (15%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            ++K+K V V  + +      G  + + C     G P   V+W  +G+ V      K   +
Sbjct: 121  LTKTKAVSVN-IRDSVTAFLGSTLRIRCSAN--GLPAPEVKWSKDGQRVV-----KDVDE 172

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL 1291
             G   L I+   + D G Y   AVN +GS      V V+E         N   I   + L
Sbjct: 173  NG--TLSIVLRRTTDAGRYVCTAVNAIGSDEAETFVYVVE--------PNYPRIVAKKGL 222

Query: 1292 EDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK 1351
              A    + +   I +            I T+  T++ L+C +   G     V+W   G+
Sbjct: 223  ATALDGRRPIAGQIGM-----------TIRTLTSTSITLKCPV--TGSPKPLVDWSKTGQ 269

Query: 1352 PIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            PI +G R         V ++  S    DSG Y C A N LGE
Sbjct: 270  PIISGDRVSVTVTGSLVIVNSRS---SDSGEYVCTARNLLGE 308



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 58/223 (26%), Positives = 93/223 (41%), Gaps = 34/223 (15%)

Query: 3698 TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDI 3757
            +V I+D++    G  +   C     G P   + W  +G+       V  +++ G   L I
Sbjct: 128  SVNIRDSVTAFLGSTLRIRCSAN--GLPAPEVKWSKDGQRV-----VKDVDENG--TLSI 178

Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRIS 3817
                  DAG Y C A N  GS      +        V+E   P+ ++ + +     GR  
Sbjct: 179  VLRRTTDAGRYVCTAVNAIGSDEAETFV-------YVVEPNYPRIVAKKGLATALDGR-- 229

Query: 3818 DAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR 3877
                  PI     +    I++ T   S  +  +C V     PK  ++W + G+ + SG R
Sbjct: 230  -----RPIAG---QIGMTIRTLT---STSITLKCPVTGS--PKPLVDWSKTGQPIISGDR 276

Query: 3878 YRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              +V   G  SL I+   + DSGEY+C A N  GED   +T++
Sbjct: 277  V-SVTVTG--SLVIVNSRSSDSGEYVCTARNLLGEDSAVSTVN 316



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 59/231 (25%), Positives = 91/231 (39%), Gaps = 46/231 (19%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGR--PFATGS 3742
            I  ED KP     +  I   + V EG  V   C V+  G P   I W + GR  P + G+
Sbjct: 14   IRTEDRKP----VSTTIGSRVTVLEGTSVSIKCPVQ--GIPAPAITWSNGGRFLPVSNGN 67

Query: 3743 RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQG 3802
             +  L++              D GEY C A +  G+   +  +T       VL  Q P  
Sbjct: 68   SILVLSN----------TRVSDTGEYMCTAMSPIGADAASTLLT-------VLAPQKPS- 109

Query: 3803 MSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLR 3862
            +SG  +     GR+       P+  T    +    S T      +R  C       P+  
Sbjct: 110  ISGPVV-----GRVI------PLTKTKAVSVNIRDSVTAFLGSTLRIRCSANGLPAPE-- 156

Query: 3863 IEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            ++W ++G+ +      + V + G  +L I+     D+G Y+C AVN  G D
Sbjct: 157  VKWSKDGQRV-----VKDVDENG--TLSIVLRRTTDAGRYVCTAVNAIGSD 200



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 41/185 (22%), Positives = 67/185 (36%), Gaps = 16/185 (8%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V EG ++   C + G P P + W  G + +  S             L +S     D G+Y
Sbjct: 32   VLEGTSVSIKCPVQGIPAPAITWSNGGRFLPVSN--------GNSILVLSNTRVSDTGEY 83

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQAD-NLPALTPLRDIVVYEGQPAQFKTQITSKIKPT- 4751
             C A +  G    +  L V  P +   + P +  +  +   +      +  +T+ +  T 
Sbjct: 84   MCTAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTKAVSVNIRDSVTAFLGSTL 143

Query: 4752 -IQWLREGALIPE---TPDFQMIHE--GNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             I+    G   PE   + D Q + +    N  L I      D G + C A  A G  E  
Sbjct: 144  RIRCSANGLPAPEVKWSKDGQRVVKDVDENGTLSIVLRRTTDAGRYVCTAVNAIGSDEAE 203

Query: 4806 AKLVV 4810
              + V
Sbjct: 204  TFVYV 208



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 9/100 (9%)

Query: 252 ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADA------QFQVQLSGNPRPRVTWFKNGQR 305
           +S EI RS  P + P     P  + + +   A        + Q +G P P V W K+GQ 
Sbjct: 764 VSPEIVRSDEPRTIPPGDGSPLTATVGDNITALTNTQVTLRCQATGTPMPSVIWSKDGQV 823

Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           L++  +H I   + + ++ ++     D G YT  A N +G
Sbjct: 824 LVSGPRHVI---NKNGSIVIQKASPVDRGRYTCTARNSHG 860



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 5/86 (5%)

Query: 3988 METTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYL 4047
            + +T    +    G P   V+W   G+P++  +R +       V +N       DSGEY+
Sbjct: 243  LTSTSITLKCPVTGSPKPLVDWSKTGQPIISGDRVSVTVTGSLVIVNSR---SSDSGEYV 299

Query: 4048 CRATNLYGMDETKAVIKTTG--KPGI 4071
            C A NL G D   + +      +PGI
Sbjct: 300  CTARNLLGEDSAVSTVNILNPVRPGI 325



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G PK  V+W + G PI + +R++       V +N +     DSG Y C A N LGE    
Sbjct: 256  GSPKPLVDWSKTGQPIISGDRVSVTVTGSLVIVNSR---SSDSGEYVCTARNLLGEDSAV 312

Query: 1798 STL 1800
            ST+
Sbjct: 313  STV 315



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 6/128 (4%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG--SAT 3780
            G P   +DW   G+P  +G RV ++   G  +L I    + D+GEY C A N  G  SA 
Sbjct: 256  GSPKPLVDWSKTGQPIISGDRV-SVTVTG--SLVIVNSRSSDSGEYVCTARNLLGEDSAV 312

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKE-EPIVSTPPKFITQIKSH 3839
            +T  I    +  I         + G     +  G+    P +   ++S P K + + K  
Sbjct: 313  STVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKGVPRPKII 372

Query: 3840 TVEESEGV 3847
             + E+E V
Sbjct: 373  WLRENEVV 380



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 6/59 (10%)

Query: 97  GNPTPVVSWTRKKAPL-VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
           G P P ++W+R    +    + Y +     T + SL+++++   D G YTCTARN +G+
Sbjct: 698 GVPAPTITWSRNGQEMPANGDGYLV-----TNNGSLILEKVSSSDIGRYTCTARNAFGK 751



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 66/278 (23%), Positives = 103/278 (37%), Gaps = 47/278 (16%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSK--------GQKPRFTTHI 3155
            G  +L +  T+ +D+G Y C A +  G    S  L  +   K        G+    T   
Sbjct: 66   GNSILVLSNTRVSDTGEYMCTAMSPIGADAASTLLTVLAPQKPSISGPVVGRVIPLTKTK 125

Query: 3156 QNIEGLKD------GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVL 3209
                 ++D      G +    C+   +  P++K  W  +GQ +     +K V + G   L
Sbjct: 126  AVSVNIRDSVTAFLGSTLRIRCSANGLPAPEVK--WSKDGQRV-----VKDVDENG--TL 176

Query: 3210 DIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGA 3269
             I   +  D+G YVC A N  G D     +         +E   P  +AK     +L G 
Sbjct: 177  SIVLRRTTDAGRYVCTAVNAIGSDEAETFV-------YVVEPNYPRIVAKKGLATALDGR 229

Query: 3270 QQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329
            +      P A       QI    + +   S   +  +     P   V+W   G+ +  G 
Sbjct: 230  R------PIA------GQIGMTIRTLTSTSITLKCPV--TGSPKPLVDWSKTGQPIISGD 275

Query: 3330 RYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDS 3367
            R        +VI++       +SGEY C A N LG DS
Sbjct: 276  RVSVTVTGSLVIVN---SRSSDSGEYVCTARNLLGEDS 310



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 4/60 (6%)

Query: 1470 PVTDSNLK-VEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
            PVT S    V+W K GQP+  G R   +   G  +L I++  + DSG Y C A NL+G D
Sbjct: 253  PVTGSPKPLVDWSKTGQPIISGDRVS-VTVTG--SLVIVNSRSSDSGEYVCTARNLLGED 309



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 8/81 (9%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S + V EG  V +     G P P ITW   G   +P          G S L +   + SD
Sbjct: 28  SRVTVLEGTSVSIKCPVQGIPAPAITWSNGG-RFLP-------VSNGNSILVLSNTRVSD 79

Query: 558 AAWYQCTAQNVAGSTATRARL 578
              Y CTA +  G+ A    L
Sbjct: 80  TGEYMCTAMSPIGADAASTLL 100



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 2/48 (4%)

Query: 4132 CRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGK 4179
            C VTG PKP V W   G  I++G R  +T  G     I  +R  D+G+
Sbjct: 252  CPVTGSPKPLVDWSKTGQPIISGDRVSVTVTG--SLVIVNSRSSDSGE 297



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 5/77 (6%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ--ATTSANLT 1000
            V+W K G+P+ +  R++       V +  +S    D+G Y C A N +G+  A ++ N+ 
Sbjct: 262  VDWSKTGQPIISGDRVSVTVTGSLVIVNSRS---SDSGEYVCTARNLLGEDSAVSTVNIL 318

Query: 1001 IVTKKDIIAESQHPGGL 1017
               +  I A   H   L
Sbjct: 319  NPVRPGIFASYGHINAL 335



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 1865 ECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINN 1924
            +C +   P P   V+W   G+ + SG R   +      +L I+     DSGEY C A N 
Sbjct: 251  KCPVTGSPKP--LVDWSKTGQPIISGDRVSVTVT---GSLVIVNSRSSDSGEYVCTARNL 305

Query: 1925 LGQ--AVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAV-QDDSFVVEKPQFG 1981
            LG+  AVS++ +    +  I     H +AL     +   +    +V  D S V+  P  G
Sbjct: 306  LGEDSAVSTVNILNPVRPGIFASYGHINALPGFSPVNVTAGQDVSVPADTSTVISCPIKG 365

Query: 1982 KP 1983
             P
Sbjct: 366  VP 367



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 6/106 (5%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           P   IV   +VT +E   I         G P  ++ W +NG +I    R+  +   G ++
Sbjct: 451 PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRY-RVTADG-VT 506

Query: 696 LDMLSLNIQDSGEYTCRAVSATG--VAETKAVLHVTPRATIERTSQ 739
           + +    + D+G +TC A +  G   A +  ++ +  + +IERT++
Sbjct: 507 MLIDGAVVSDTGSFTCEAENFAGKDKATSAVIVKIPAKPSIERTNK 552



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 4/75 (5%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +N+   E   I   CN      P  ++ W  N   +  G RY+ T D   V++ I     
Sbjct: 459  DNVTVLEDSTIRIVCNATGL--PAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGAVV 514

Query: 2841 EDSGIYTCKATNSKG 2855
             D+G +TC+A N  G
Sbjct: 515  SDTGSFTCEAENFAG 529



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 55/210 (26%), Positives = 84/210 (40%), Gaps = 38/210 (18%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            +  +EGT+V ++C +Q  G     + W         G RF P    + + L L +    D
Sbjct: 30   VTVLEGTSVSIKCPVQ--GIPAPAITW-------SNGGRFLPVSNGNSI-LVLSNTRVSD 79

Query: 1380 SGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDES 1439
            +G Y C A + +G    S  L V+A        Q PS    +  +       KT  +  S
Sbjct: 80   TGEYMCTAMSPIGADAASTLLTVLAP-------QKPSISGPV--VGRVIPLTKTKAV--S 128

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            V I+   VT          G  +   C    +    +K  W K+GQ V      + + + 
Sbjct: 129  VNIRDS-VT-------AFLGSTLRIRCSANGLPAPEVK--WSKDGQRVV-----KDVDEN 173

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
            G   L I+     D+G Y C AVN +G+DE
Sbjct: 174  G--TLSIVLRRTTDAGRYVCTAVNAIGSDE 201



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 3/82 (3%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   I W +NGQ + A+     +   G + L+ +S +  D G YTC A +A G     
Sbjct: 698 GVPAPTITWSRNGQEMPANGDGYLVTNNGSLILEKVSSS--DIGRYTCTARNAFGKDNAN 755

Query: 724 AVLHVTPRATIERT-SQHPETL 744
           + ++V    + E   S  P T+
Sbjct: 756 STVNVMDPVSPEIVRSDEPRTI 777



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   V+W +  + I    R++ T      S+ I + R  D G Y+C A NLLGE
Sbjct: 256  GSPKPLVDWSKTGQPIISGDRVSVTVTG---SLVIVNSRSSDSGEYVCTARNLLGE 308



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 5/77 (6%)

Query: 1194 NIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVR 1253
            +I L+C +   G P   V+W   G+ +  G R         V   I+++ S+D+GEY   
Sbjct: 247  SITLKCPVT--GSPKPLVDWSKTGQPIISGDRVSVTVTGSLV---IVNSRSSDSGEYVCT 301

Query: 1254 AVNHLGSAHTSAIVRVI 1270
            A N LG     + V ++
Sbjct: 302  ARNLLGEDSAVSTVNIL 318



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 16/60 (26%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W ++G+ + A+       N G  +L ++ V+  D G YTC A NA G+   ++ + ++
Sbjct: 704  ITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGKDNANSTVNVM 761



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 11/96 (11%)

Query: 3138 LECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTR 3197
            ++ + +++ +KP  TT    +  L +G S   +C V  +  P   I W + G       R
Sbjct: 10   MDVIIRTEDRKPVSTTIGSRVTVL-EGTSVSIKCPVQGIPAP--AITWSNGG-------R 59

Query: 3198 IKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
               VS+ G  +L ++ T+  D+GEY+C A +  G D
Sbjct: 60   FLPVSN-GNSILVLSNTRVSDTGEYMCTAMSPIGAD 94



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 10/107 (9%)

Query: 2358 SAEPFKRPEIPEPVTRQRPVFTQPLQNI---DNIQ--EGQTAHFDCRLIPVGDPTLKVEW 2412
            S EP ++P+I  P     P+   P   I   DN+   E  T    C     G P  +V W
Sbjct: 429  SLEP-RKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTW 485

Query: 2413 FRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             +N   I    R   T D   V+M I      D G + C A N  G+
Sbjct: 486  RQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGK 530



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 3/74 (4%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQ-ATTSANLT 1000
            RV W ++G  +    R     +   V + I    V D G +TC A N  G+   TSA + 
Sbjct: 482  RVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGKDKATSAVIV 539

Query: 1001 IVTKKDIIAESQHP 1014
             +  K  I  +  P
Sbjct: 540  KIPAKPSIERTNKP 553



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 7/69 (10%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIP 4170
            PV  ++   VTV EG      C V G P P + W        NG R+    +G     + 
Sbjct: 21   PVSTTIGSRVTVLEGTSVSIKCPVQGIPAPAITW-------SNGGRFLPVSNGNSILVLS 73

Query: 4171 KTRQYDTGK 4179
             TR  DTG+
Sbjct: 74   NTRVSDTGE 82



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 10/83 (12%)

Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
           VT +EG  +  +  ++  G P   I W   G+ +  S+        G   L + +  + D
Sbjct: 30  VTVLEGTSVSIKCPVQ--GIPAPAITWSNGGRFLPVSN--------GNSILVLSNTRVSD 79

Query: 706 SGEYTCRAVSATGVAETKAVLHV 728
           +GEY C A+S  G      +L V
Sbjct: 80  TGEYMCTAMSPIGADAASTLLTV 102



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 10/82 (12%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V EG ++ ++C ++  G P   + W + GR + V +        G   L + +   +DTG
Sbjct: 32   VLEGTSVSIKCPVQ--GIPAPAITWSNGGRFLPVSN--------GNSILVLSNTRVSDTG 81

Query: 1249 EYTVRAVNHLGSAHTSAIVRVI 1270
            EY   A++ +G+   S ++ V+
Sbjct: 82   EYMCTAMSPIGADAASTLLTVL 103


>SB_59380| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1226

 Score = 99.1 bits (236), Expect = 8e-20
 Identities = 106/411 (25%), Positives = 160/411 (38%), Gaps = 42/411 (10%)

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            +PP F ++            +        P+    W ++   IK  PD + H   T   L
Sbjct: 85   QPPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGARIK--PDDR-HVVLTSGAL 141

Query: 4469 IIRQV------FVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
             I+ V      F  D  V+  +A NR GT        V  ++      ++   F    Q+
Sbjct: 142  RIQSVQGRRKGFGNDEGVYQCLASNRAGT--------VASRKVTLHIAVLSRKFEEQPQS 193

Query: 4523 VNVTSGQLVRLDTKVTGTKPI-DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            +N   G   R   KV    P   + W  NG+ + P  R+ +L       L I      D 
Sbjct: 194  INAWEGTTARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGA---LQIHNVQQVDQ 250

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G Y+CVA N A   R +         T      Q K++  P     P    +++  +A+ 
Sbjct: 251  GTYQCVASNIARIRRSN---------TATLTVQQAKSSKQPNFTTIPSNTSVISGEEAV- 300

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
              C   G P+PTVQW K     +   Y  +++      LRI  A P+D G+Y C+   S 
Sbjct: 301  LECIATGVPVPTVQWKKVGGADRAYDY-SLAKPGG-CNLRIRSASPKDGGEYMCIVSASG 358

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTP-LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
              +T +  L V +P    N P L   L DI    G     +   T    P I WL+ G  
Sbjct: 359  RSMTHSTFLSVQEPPHFINTPKLPKGLLDI----GATLTLQCSATGVPPPRITWLKNG-- 412

Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
              E    Q    G N  L+I +   +D+G + C A    G V+TS +++V+
Sbjct: 413  -KELVGNQR-QSGINNDLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVR 461



 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 78/315 (24%), Positives = 127/315 (40%), Gaps = 45/315 (14%)

Query: 267 KIAQKPRNSKLQEGADAQFQVQLS-GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           K  ++P++    EG  A+F  ++    P P ++W  NGQ ++ S +H ++    +  L++
Sbjct: 186 KFEEQPQSINAWEGTTARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLP---NGALQI 242

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
            N Q+ D G Y  +A N                     + +RS   T T Q+        
Sbjct: 243 HNVQQVDQGTYQCVASN-------------------IARIRRSNTATLTVQQ-------- 275

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNE 444
           ++ +  P F  +  +  V  G+    +C  TG P P V W  +       DY+    + +
Sbjct: 276 AKSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVGGADRAYDYS----LAK 331

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV-APKFVERFSTLNVR 503
            G   L I + +  D G   C+             L+V E    +  PK  +    L++ 
Sbjct: 332 PGGCNLRIRSASPKDGGEYMCIVSASGRSMTHSTFLSVQEPPHFINTPKLPK--GLLDI- 388

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            G  + L   A G P PRITW K+G  ++ N        G  + L I      D+  YQC
Sbjct: 389 -GATLTLQCSATGVPPPRITWLKNGKELVGNQ----RQSGINNDLVIQSLSTKDSGVYQC 443

Query: 564 TAQNVAGSTATRARL 578
            A+N  GS  T  R+
Sbjct: 444 FAENDIGSVQTSTRV 458



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 82/333 (24%), Positives = 127/333 (38%), Gaps = 37/333 (11%)

Query: 246 GESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQR 305
           G+S + I  ++  S   + PP+  ++P        +  Q        P  R  W K+G R
Sbjct: 67  GKSSIDIYFDLGGSSNLLQPPRFVEEPSAVIALRKSTVQINCSTIATPVARTIWLKDGAR 126

Query: 306 LINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQD 365
           +   ++H ++T+     LR+++ Q    G       N  G      Y  + S     V  
Sbjct: 127 IKPDDRHVVLTSG---ALRIQSVQGRRKGF-----GNDEGV-----YQCLASNRAGTVAS 173

Query: 366 QRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVT 424
           ++         R+ EE+         PQ +      +  EG   RF C+V    P P ++
Sbjct: 174 RKVTLHIAVLSRKFEEQ---------PQSI------NAWEGTTARFSCKVKKAYPAPSIS 218

Query: 425 WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVI 483
           W  N + I     H +L N     AL I NV   D G   CVA N +    +    L V 
Sbjct: 219 WEHNGQVIVPSKRHVVLPNG----ALQIHNVQQVDQGTYQCVASNIARIRRSNTATLTVQ 274

Query: 484 EKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
           + +    P F    S  +V  GE  VL   A G P P + W+K G       +  +   G
Sbjct: 275 QAKSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVG-GADRAYDYSLAKPG 333

Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
           G + L I  A   D   Y C   + +G + T +
Sbjct: 334 GCN-LRIRSASPKDGGEYMCIV-SASGRSMTHS 364



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 6/100 (6%)

Query: 265 PPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           PP     P+  K  L  GA    Q   +G P PR+TW KNG+ L+ + +   I    +  
Sbjct: 372 PPHFINTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGI----NND 427

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
           L +++    DSG Y   AEN  G + TS  + V     +Y
Sbjct: 428 LVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVRRSVNTY 467



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 52/200 (26%), Positives = 79/200 (39%), Gaps = 18/200 (9%)

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
            K SK P FT       V   E+A  E    G P+P ++W +       + D+ +      
Sbjct: 277  KSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVG-GADRAYDYSLAKPGGC 335

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN- 4524
            + L IR    +D   +  +    G +   S  L V+E          PP F  T +    
Sbjct: 336  N-LRIRSASPKDGGEYMCIVSASGRSMTHSTFLSVQE----------PPHFINTPKLPKG 384

Query: 4525 -VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
             +  G  + L    TG  P  + WLKNGK++  + R   +  D    L+I     +DSG 
Sbjct: 385  LLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGINND----LVIQSLSTKDSGV 440

Query: 4584 YECVAINSAGEARCDAECVV 4603
            Y+C A N  G  +     +V
Sbjct: 441  YQCFAENDIGSVQTSTRVLV 460



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 46/158 (29%), Positives = 65/158 (41%), Gaps = 10/158 (6%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W +NG+ I  S R   V   G   L+I   +  D GTY C A+N       +     V
Sbjct: 217  ISWEHNGQVIVPSKR-HVVLPNG--ALQIHNVQQVDQGTYQCVASNIARIRRSNTATLTV 273

Query: 3142 DKSKGQK-PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
             ++K  K P FTT I +   +  G+ A  EC    V  P   ++W   G   R      +
Sbjct: 274  QQAKSSKQPNFTT-IPSNTSVISGEEAVLECIATGVPVP--TVQWKKVGGADR--AYDYS 328

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRAT 3238
            ++  G   L I      D GEY+C   +  G   T +T
Sbjct: 329  LAKPGGCNLRIRSASPKDGGEYMC-IVSASGRSMTHST 365



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 50/187 (26%), Positives = 73/187 (39%), Gaps = 16/187 (8%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            +PP F      ++ + +  +     S I T     +  W  +G  I+   R   + +  +
Sbjct: 85   QPPRFVEEPSAVIALRKSTV-QINCSTIATPVARTI--WLKDGARIKPDDRHVVLTSGAL 141

Query: 3106 VVLEILGTKT---TDSGTYSCRATNKWGQ-AEISVKLECVDKSKGQKPRFTTHIQNIEGL 3161
             +  + G +     D G Y C A+N+ G  A   V L     S+    +F    Q+I   
Sbjct: 142  RIQSVQGRRKGFGNDEGVYQCLASNRAGTVASRKVTLHIAVLSR----KFEEQPQSINAW 197

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
             +G +A F C V     P   I W HNGQ +  S R   V   G   L I   Q  D G 
Sbjct: 198  -EGTTARFSCKVKKAY-PAPSISWEHNGQVIVPSKR-HVVLPNG--ALQIHNVQQVDQGT 252

Query: 3222 YVCRAYN 3228
            Y C A N
Sbjct: 253  YQCVASN 259



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 7/104 (6%)

Query: 1439 SVTIKPRFVTRPKSIENVIE-GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH 1497
            SV   P F+  PK  + +++ G  +  +C    V     ++ W KNG+ +    R   I+
Sbjct: 368  SVQEPPHFINTPKLPKGLLDIGATLTLQCSATGVPPP--RITWLKNGKELVGNQRQSGIN 425

Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTD 1541
            +     L I  L  +DSG+Y C A N +G+ + S R+  R + +
Sbjct: 426  N----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVRRSVN 465



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 41/144 (28%), Positives = 59/144 (40%), Gaps = 12/144 (8%)

Query: 3509 SMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPS--D 3566
            S+   G  N+ + S  PK   G    I +  G S T  T     E   PP F  TP    
Sbjct: 328  SLAKPGGCNLRIRSASPKD-GGEYMCIVSASGRSMTHSTFLSVQE---PPHFINTPKLPK 383

Query: 3567 LILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRD 3626
             +L   ++   +C    V     R+ W  NGK L+   R   IN+     L I  +  +D
Sbjct: 384  GLLDIGATLTLQCSATGVPPP--RITWLKNGKELVGNQRQSGINND----LVIQSLSTKD 437

Query: 3627 AGLYTCKATNRHGEATVSCKLQVK 3650
            +G+Y C A N  G    S ++ V+
Sbjct: 438  SGVYQCFAENDIGSVQTSTRVLVR 461



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 7/101 (6%)

Query: 1838 VAVNQAPRFITQLNGPTKLSE-GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++V + P FI     P  L + G +   +C     P P  R+ W  NGK L    R    
Sbjct: 367  LSVQEPPHFINTPKLPKGLLDIGATLTLQCSATGVPPP--RITWLKNGKELVGNQRQSGI 424

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            N+     L I ++  +DSG Y C A N++G   +S R+ V+
Sbjct: 425  NN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVR 461



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 31/83 (37%), Positives = 37/83 (44%), Gaps = 5/83 (6%)

Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDS 2179
            N  EG  A F C+V+    P  +I W HNGQ I    R+    +    AL I      D 
Sbjct: 195  NAWEGTTARFSCKVKKAY-PAPSISWEHNGQVIVPSKRHVVLPNG---ALQIHNVQQVDQ 250

Query: 2180 GTYMCKATNKLG-EAVNTCTLKV 2201
            GTY C A+N       NT TL V
Sbjct: 251  GTYQCVASNIARIRRSNTATLTV 273



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 4113 FVSLPDAVTVEEGEWARFCCRVT-GHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPK 4171
            F   P ++   EG  ARF C+V   +P P + W  NG  IV   R+ +  +G     I  
Sbjct: 187  FEEQPQSINAWEGTTARFSCKVKKAYPAPSISWEHNGQVIVPSKRHVVLPNGA--LQIHN 244

Query: 4172 TRQYDTGKIEVI 4183
             +Q D G  + +
Sbjct: 245  VQQVDQGTYQCV 256



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 7/78 (8%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG-NHALMITNVTLSDSGVVT 464
           G      C  TG P P +TW  N +++  +        +SG N+ L+I +++  DSGV  
Sbjct: 389 GATLTLQCSATGVPPPRITWLKNGKELVGNQR------QSGINNDLVIQSLSTKDSGVYQ 442

Query: 465 CVARNKSGETAFQCRLNV 482
           C A N  G      R+ V
Sbjct: 443 CFAENDIGSVQTSTRVLV 460



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 20/66 (30%), Positives = 38/66 (57%), Gaps = 4/66 (6%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P  R+ WL+NG  +  + R + +++     L ++ ++ +DSG Y C A N++G   TS
Sbjct: 400  GVPPPRITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTS 455

Query: 1798 STLFVQ 1803
            + + V+
Sbjct: 456  TRVLVR 461



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 5/79 (6%)

Query: 2378 FTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMT 2437
            F +  Q+I N  EG TA F C+ +    P   + W  N ++I  S R     +    ++ 
Sbjct: 187  FEEQPQSI-NAWEGTTARFSCK-VKKAYPAPSISWEHNGQVIVPSKRHVVLPNG---ALQ 241

Query: 2438 ISHVRDEDEGVYMCRASNL 2456
            I +V+  D+G Y C ASN+
Sbjct: 242  IHNVQQVDQGTYQCVASNI 260



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 12/108 (11%)

Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
            V+E    +  P+  + L +I    G  + L+C     G    R+ W  NGK +  G++ +
Sbjct: 369  VQEPPHFINTPKLPKGLLDI----GATLTLQC--SATGVPPPRITWLKNGKEL-VGNQRQ 421

Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDL 1408
                 D V   + S+  +DSGVY C A N +G   TS   RV+ ++ +
Sbjct: 422  SGINNDLV---IQSLSTKDSGVYQCFAENDIGSVQTS--TRVLVRRSV 464



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
           V  PP FI   K    +         +    G P  +I WLKNG+ +  + R + I    
Sbjct: 369 VQEPPHFINTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGINN-- 426

Query: 693 YISLDMLSLNIQDSGEYTCRAVSATGVAET 722
              L + SL+ +DSG Y C A +  G  +T
Sbjct: 427 --DLVIQSLSTKDSGVYQCFAENDIGSVQT 454



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 4/60 (6%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            R+ WLK+G+ +  + R +   N     L I+S++  D+G Y C A N IG   TS  + +
Sbjct: 405  RITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLV 460



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 9/100 (9%)

Query: 770 PQFIR-PLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYV 828
           P FI  P    G L  G     +   T V  P  R+ W K+G+ +  + R + I N    
Sbjct: 373 PHFINTPKLPKGLLDIGATLTLQCSATGVPPP--RITWLKNGKELVGNQRQSGINN---- 426

Query: 829 SLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARSTV 868
            L I  L  +D+G Y   A N +G ++ T S RV  R +V
Sbjct: 427 DLVIQSLSTKDSGVYQCFAENDIG-SVQT-STRVLVRRSV 464



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 11/123 (8%)

Query: 3525 PKGMEGTIDKI--AALEGYSGTVDTLTPEAESGN---PPEFTTTPSDLILSENSSAHFEC 3579
            P+  E T+ ++  A L+G S ++D       S N   PP F   PS +I    S+    C
Sbjct: 50   PRDPERTLVRLDYAKLQGKS-SIDIYFDLGGSSNLLQPPRFVEEPSAVIALRKSTVQINC 108

Query: 3580 RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGV---YQRDAGLYTCKATN 3636
              I    +  R  W  +G  +    R   +      I  + G    +  D G+Y C A+N
Sbjct: 109  STIATPVA--RTIWLKDGARIKPDDRHVVLTSGALRIQSVQGRRKGFGNDEGVYQCLASN 166

Query: 3637 RHG 3639
            R G
Sbjct: 167  RAG 169



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 11/129 (8%)

Query: 3405 VRRKDTS---VEEEKG-KAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
            +RR +T+   V++ K  K P FT   SN   +  GE A  E   T    P   V+W   G
Sbjct: 263  IRRSNTATLTVQQAKSSKQPNFTTIPSNTSVI-SGEEAVLECIATGVPVPT--VQWKKVG 319

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS-MKVQGKRNII 3519
             + +A     +    G   L I    P+D GEY+C   +  G ++T ++ + VQ   + I
Sbjct: 320  GADRAYDY--SLAKPGGCNLRIRSASPKDGGEYMC-IVSASGRSMTHSTFLSVQEPPHFI 376

Query: 3520 LESQLPKGM 3528
               +LPKG+
Sbjct: 377  NTPKLPKGL 385



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G P  RI W  NG+      R   +N+     L I  +  +D+G Y C A N  GS  T+
Sbjct: 400  GVPPPRITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTS 455

Query: 3783 AKI 3785
             ++
Sbjct: 456  TRV 458



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 4/78 (5%)

Query: 3559 EFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILE 3618
            +F   P  +   E ++A F C++     +   + W HNG+ ++   R   + +     L+
Sbjct: 186  KFEEQPQSINAWEGTTARFSCKVKKAYPAPS-ISWEHNGQVIVPSKRHVVLPNGA---LQ 241

Query: 3619 IGGVYQRDAGLYTCKATN 3636
            I  V Q D G Y C A+N
Sbjct: 242  IHNVQQVDQGTYQCVASN 259



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 28/98 (28%), Positives = 37/98 (37%), Gaps = 4/98 (4%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP FI   K        G     +      P  RI W +NGK L    R   + +  
Sbjct: 369  VQEPPHFINTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQRQSGINN-- 426

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
               L I  +  +DSG Y C A ND G   T   +  ++
Sbjct: 427  --DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLVRR 462



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 2/49 (4%)

Query: 4110 PPVFVSLPDAVT--VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            PP F++ P      ++ G      C  TG P PR+ WL NG  +V   R
Sbjct: 372  PPHFINTPKLPKGLLDIGATLTLQCSATGVPPPRITWLKNGKELVGNQR 420



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  +I W KNG  L  G + +S  +  LV   I SL   DSG+Y C A N +G   ++  
Sbjct: 402  PPPRITWLKNGKELV-GNQRQSGINNDLV---IQSLSTKDSGVYQCFAENDIGSVQTSTR 457

Query: 2732 IKI 2734
            + +
Sbjct: 458  VLV 460



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 4/67 (5%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            ++ W  N K L    R +  NN     L I S   +DSG Y C A N +G   TS   +V
Sbjct: 405  RITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLV 460

Query: 1670 HSKKSIY 1676
                + Y
Sbjct: 461  RRSVNTY 467



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 2253 HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDA 2312
            + +EG TA F C+V+  + P   I + HNG+ +  + R H+    G  +L I +    D 
Sbjct: 195  NAWEGTTARFSCKVKKAY-PAPSISWEHNGQVIVPSKR-HVVLPNG--ALQIHNVQQVDQ 250

Query: 2313 GEYSVKAIN 2321
            G Y   A N
Sbjct: 251  GTYQCVASN 259



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 17/48 (35%), Positives = 24/48 (50%)

Query: 4097 TPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            T    V+++K+   P F ++P   +V  GE A   C  TG P P V W
Sbjct: 268  TATLTVQQAKSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQW 315



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/86 (29%), Positives = 32/86 (37%), Gaps = 4/86 (4%)

Query: 61  ITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSM 120
           +T  +      P F  I  N     G  A  E    G P P V W +K         YS+
Sbjct: 271 LTVQQAKSSKQPNFTTIPSNTSVISGEEAVLECIATGVPVPTVQW-KKVGGADRAYDYSL 329

Query: 121 RYNEQTGDVSLLIKQIGPGDEGEYTC 146
               + G  +L I+   P D GEY C
Sbjct: 330 ---AKPGGCNLRIRSASPKDGGEYMC 352



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 2/93 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P     P N+ +  G +A  +   +G P P V W K G    +      +       LR+
Sbjct: 282 PNFTTIPSNTSVISGEEAVLECIATGVPVPTVQWKKVGG--ADRAYDYSLAKPGGCNLRI 339

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           R+    D G Y  +       +  S +L+V+ P
Sbjct: 340 RSASPKDGGEYMCIVSASGRSMTHSTFLSVQEP 372



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 5/90 (5%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            ++PP F+   +    L+++  T    Q +  G P  ++ W  NGK L+   R + I +  
Sbjct: 370  QEPPHFINTPKLPKGLLDIGAT-LTLQCSATGVPPPRITWLKNGKELVGNQRQSGINN-D 427

Query: 4030 YVAMNFGWVYPEDSGEYLCRATNLYGMDET 4059
             V  +      +DSG Y C A N  G  +T
Sbjct: 428  LVIQSLS---TKDSGVYQCFAENDIGSVQT 454



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G  + L+C     G P  R+ W  NG+ + VG++ ++  +   V   +   ++ D+G Y 
Sbjct: 389  GATLTLQC--SATGVPPPRITWLKNGKEL-VGNQRQSGINNDLVIQSL---STKDSGVYQ 442

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVT 1277
              A N +GS  TS   RV+ R  + T
Sbjct: 443  CFAENDIGSVQTS--TRVLVRRSVNT 466



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 4/70 (5%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P  +I W  N K L    R    ++     L I     +DSG+Y C A N  GS  TS  
Sbjct: 402  PPPRITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTR 457

Query: 2863 LRCTGDKNIY 2872
            +      N Y
Sbjct: 458  VLVRRSVNTY 467



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 11/123 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG     I W  NGK +  + R   +     +V++ L TK  DSG Y C A N  G  + 
Sbjct: 399  TGVPPPRITWLKNGKELVGNQRQSGIN--NDLVIQSLSTK--DSGVYQCFAENDIGSVQT 454

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRH 3194
            S ++  V +S    P       N+ G+    S     + +P   P+  + +  N QP   
Sbjct: 455  STRV-LVRRSVNTYPPL-----NVTGV-GISSEEVNISWLPPRGPEQVLAYSINYQPADK 507

Query: 3195 STR 3197
            S++
Sbjct: 508  SSK 510



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 6/67 (8%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W  NGK++    R    ++     L I S+  +DSGVY   A N  G  Q S  + V 
Sbjct: 406  ITWLKNGKELVGNQRQSGINN----DLVIQSLSTKDSGVYQCFAENDIGSVQTSTRVLV- 460

Query: 1137 TRSSIDT 1143
             R S++T
Sbjct: 461  -RRSVNT 466


>SB_57926| Best HMM Match : I-set (HMM E-Value=3.5e-39)
          Length = 788

 Score = 97.1 bits (231), Expect = 3e-19
 Identities = 80/296 (27%), Positives = 126/296 (42%), Gaps = 28/296 (9%)

Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577
            ++ +   VT    V    +  GT    + W  NG++V  + R  +    G YT+L  +A 
Sbjct: 238  VSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESV-SSSGDYTILQTKA- 295

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEG 4637
             +DSG  +C+A N AG     A                 K    P  I  P +D  V  G
Sbjct: 296  -EDSGVIQCLASNDAGHVMGRA---------------LLKILGIPIWITLPPRDTSVTIG 339

Query: 4638 QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
            + + F C+  G P PTV W+KG  +I  S          +  L+I+     D G Y C+A
Sbjct: 340  ETVVFDCQTRGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYTCLA 399

Query: 4698 YNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQIT--SKIKPTIQWL 4755
             NS G    +A+LKV       N+    P R I + +G        +   S I     W 
Sbjct: 400  RNSLGVKNASAELKVL---AQTNITTPLPPRTIAI-KGYSITLAVGVNKDSLISLRFTWT 455

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            ++G+ + + P  Q++  G+ A+  +   ++ D GT+ C  ++  G   TS  LVV+
Sbjct: 456  KDGSSVTD-PRMQILANGSLAITAV---HDSDAGTYKCVVSSDVGNASTSTVLVVQ 507



 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 52/172 (30%), Positives = 79/172 (45%), Gaps = 7/172 (4%)

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
            SC+  G P PT+ WY   + +  +    +S + D YT+  ++A  ED G  +C+A N AG
Sbjct: 254  SCRARGTPTPTITWYNNGRRVFANSRESVSSSGD-YTILQTKA--EDSGVIQCLASNDAG 310

Query: 4703 RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
             V   A LK+        LP     RD  V  G+   F  Q      PT+ W +  ++I 
Sbjct: 311  HVMGRALLKILGIPIWITLPP----RDTSVTIGETVVFDCQTRGNPTPTVTWWKGSSVID 366

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             +      H+ ++  L I  T   D G +TC A  + G    SA+L V ++T
Sbjct: 367  ISSPSTRFHQKSDGALQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQT 418



 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 50/167 (29%), Positives = 78/167 (46%), Gaps = 10/167 (5%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           CR  G P P +TW+ N R++    N +  V+ SG++ ++ T     DSGV+ C+A N +G
Sbjct: 255 CRARGTPTPTITWYNNGRRV--FANSRESVSSSGDYTILQTKA--EDSGVIQCLASNDAG 310

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI- 531
               +  L ++     +      R +++ +  GE VV + +  G PTP +TW K    I 
Sbjct: 311 HVMGRALLKILGIPIWIT--LPPRDTSVTI--GETVVFDCQTRGNPTPTVTWWKGSSVID 366

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           I +P  R H     + L I   +  D   Y C A+N  G     A L
Sbjct: 367 ISSPSTRFHQKSDGA-LQITGTQRVDNGVYTCLARNSLGVKNASAEL 412



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 51/176 (28%), Positives = 79/176 (44%), Gaps = 7/176 (3%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
           +D  VT G+   FDC+  G P P VTW+     I D  +     ++  + AL IT     
Sbjct: 332 RDTSVTIGETVVFDCQTRGNPTPTVTWWKGSSVI-DISSPSTRFHQKSDGALQITGTQRV 390

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           D+GV TC+ARN  G       L V+ +  +  P      +         V +N  ++   
Sbjct: 391 DNGVYTCLARNSLGVKNASAELKVLAQTNITTPLPPRTIAIKGYSITLAVGVNKDSL--I 448

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
           + R TW KDG   + +P ++I  +G   +L I     SDA  Y+C   +  G+ +T
Sbjct: 449 SLRFTWTKDG-SSVTDPRMQILANG---SLAITAVHDSDAGTYKCVVSSDVGNAST 500



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 71/287 (24%), Positives = 106/287 (36%), Gaps = 39/287 (13%)

Query: 4436 GEPLPLIKWYRENFPI-KNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            G P P I WY     +  NS +    + S+     I Q   EDS V   +A N  G    
Sbjct: 259  GTPTPTITWYNNGRRVFANSRE----SVSSSGDYTILQTKAEDSGVIQCLASNDAGHVMG 314

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
             A L +           +P   TL  ++ +VT G+ V  D +  G     V W K    +
Sbjct: 315  RALLKILG---------IPIWITLPPRDTSVTIGETVVFDCQTRGNPTPTVTWWKGSSVI 365

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                 +    +     L I      D+G Y C+A NS G     AE  V           
Sbjct: 366  DISSPSTRFHQKSDGALQITGTQRVDNGVYTCLARNSLGVKNASAELKVL---------- 415

Query: 4615 QTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQ--WYK-GDKLIKPSKYFQ 4670
                  A   I  PL  + +A +G +I  +  +    L +++  W K G  +  P    +
Sbjct: 416  ------AQTNITTPLPPRTIAIKGYSITLAVGVNKDSLISLRFTWTKDGSSVTDP----R 465

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
            M   A+  +L I+     D G YKCV  +  G  + +  L V   +Q
Sbjct: 466  MQILANG-SLAITAVHDSDAGTYKCVVSSDVGNASTSTVLVVQDANQ 511



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 31/95 (32%), Positives = 43/95 (45%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P  I   PR++ +  G    F  Q  GNP P VTW+K    +  S+        +   L+
Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTRGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQ 383

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           +  TQ+ D+G YT LA N  G    S  L V + T
Sbjct: 384 ITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQT 418



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 47/179 (26%), Positives = 77/179 (43%), Gaps = 13/179 (7%)

Query: 4426 EQARFEVEFDGEPLPLIKWYRENFPIK-NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484
            E   F+ +  G P P + W++ +  I  +SP  + H  S  ++ I     V D+ V+  +
Sbjct: 340  ETVVFDCQTRGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRV-DNGVYTCL 398

Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID 4544
            A N  G    SA L V  +        +PP  T+  +  ++T    V  D+ ++    + 
Sbjct: 399  ARNSLGVKNASAELKVLAQTNITTP--LPPR-TIAIKGYSITLAVGVNKDSLIS----LR 451

Query: 4545 VYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
              W K+G  V  D R +IL      +L I   +  D+G Y+CV  +  G A      VV
Sbjct: 452  FTWTKDGSSVT-DPRMQILANG---SLAITAVHDSDAGTYKCVVSSDVGNASTSTVLVV 506



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 7/85 (8%)

Query: 2123 EGDRAHFECRV----EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAED 2178
            +G    FEC V         P  TI W++NG+++ A  R   +    Y    IL T AED
Sbjct: 241  KGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYT---ILQTKAED 297

Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAG 2203
            SG   C A+N  G  +    LK+ G
Sbjct: 298  SGVIQCLASNDAGHVMGRALLKILG 322



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 2/68 (2%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYM 2450
            G+T  FDC+    G+PT  V W++   +I+ SS  T+ H     ++ I+  +  D GVY 
Sbjct: 339  GETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396

Query: 2451 CRASNLLG 2458
            C A N LG
Sbjct: 397  CLARNSLG 404



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 2/68 (2%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G    F+ + RGNPTP V+W  K + +++ +  S R++ Q  D +L I      D G YT
Sbjct: 339 GETVVFDCQTRGNPTPTVTWW-KGSSVIDISSPSTRFH-QKSDGALQITGTQRVDNGVYT 396

Query: 146 CTARNQYG 153
           C ARN  G
Sbjct: 397 CLARNSLG 404



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           + RA GTPTP ITW  +G  +  N    + + G  + L   + KA D+   QC A N AG
Sbjct: 254 SCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYTIL---QTKAEDSGVIQCLASNDAG 310

Query: 571 STATRARL 578
               RA L
Sbjct: 311 HVMGRALL 318



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G+ + F+C    +  PT  + W+  +  +   +     H  S  +L IT T   D+G+YT
Sbjct: 339  GETVVFDCQTRGNPTPT--VTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396

Query: 2848 CKATNSKGSATTSGSLRCTGDKNI 2871
            C A NS G    S  L+     NI
Sbjct: 397  CLARNSLGVKNASAELKVLAQTNI 420



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 2/101 (1%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P+++        V+ G+ +  +C+    G+PT  V W+     + + S    ++     A
Sbjct: 324  PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT 1277
            L I      D G YT  A N LG  + SA ++V+ +++I T
Sbjct: 382  LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNITT 422



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 2/99 (2%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P ++T P    +V  G+ V F+C+     +    V W+K    + I       H     A
Sbjct: 324  PIWITLPPRDTSVTIGETVVFDCQTRG--NPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDI 1542
            L I      D+G+YTC A N +G    S  L   + T+I
Sbjct: 382  LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%)

Query: 1058 GQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYT 1117
            G++  F+ +   + + T TV W+     I  ++    +H     AL I   +  D+GVYT
Sbjct: 339  GETVVFDCQT--RGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396

Query: 1118 VVARNAAGEAQLSASMTVETRSSIDT 1143
             +ARN+ G    SA + V  +++I T
Sbjct: 397  CLARNSLGVKNASAELKVLAQTNITT 422



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 44/159 (27%), Positives = 64/159 (40%), Gaps = 16/159 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G  +  I W+ NG+ + A+ R  +V + G     IL TK  DSG   C A+N  G     
Sbjct: 259  GTPTPTITWYNNGRRVFANSR-ESVSSSGDYT--ILQTKAEDSGVIQCLASNDAGHVMGR 315

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM--- 3192
              L+ +       P + T       +  G++  F+C      +P   + W+     +   
Sbjct: 316  ALLKILG-----IPIWITLPPRDTSVTIGETVVFDCQT--RGNPTPTVTWWKGSSVIDIS 368

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              STR    SD     L I  TQ  D+G Y C A N  G
Sbjct: 369  SPSTRFHQKSD---GALQITGTQRVDNGVYTCLARNSLG 404



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 3/65 (4%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
           G P P +TW+ NG+R+  +++  + ++ ++T L+   T+  DSG    LA N  G ++  
Sbjct: 259 GTPTPTITWYNNGRRVFANSRESVSSSGDYTILQ---TKAEDSGVIQCLASNDAGHVMGR 315

Query: 351 GYLAV 355
             L +
Sbjct: 316 ALLKI 320



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMK 1773
            T+P +D  V   +   F+ +    G+P   V W +    I+ S+  T  H     AL + 
Sbjct: 328  TLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQIT 385

Query: 1774 YVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
                 D+G YTC A N LG    S+ L V ++ ++
Sbjct: 386  GTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 2/99 (2%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P+++T      ++  G+   F+C+     +P  T+ W+     I         H     A
Sbjct: 324  PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
            L I  T   D+G Y C A N LG    +  LKV    NI
Sbjct: 382  LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 24/71 (33%), Positives = 33/71 (46%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G+ T  V W K    ++ SS  T F      AL I      D G YTC A N++G    S
Sbjct: 350  GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYTCLARNSLGVKNAS 409

Query: 997  ANLTIVTKKDI 1007
            A L ++ + +I
Sbjct: 410  AELKVLAQTNI 420



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 3/109 (2%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           P    +P +  +   G  + F+ +    G+PT  + W K    I+ SS  T   +    +
Sbjct: 324 PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETL 744
           L +      D+G YTC A ++ GV    A L V  +  I  T   P T+
Sbjct: 382 LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI-TTPLPPRTI 429



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P +IT     T ++ G++  ++C+    P P   V W+    V+         +     A
Sbjct: 324  PIWITLPPRDTSVTIGETVVFDCQTRGNPTPT--VTWWKGSSVIDISSPSTRFHQKSDGA 381

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            L I      D+G YTC A N+LG   +S  L V ++ +I
Sbjct: 382  LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 785 GRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYT 844
           G    F+ Q     +PT  V W+K    I  SS  T        +L I   +  D G YT
Sbjct: 339 GETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396

Query: 845 VRAVNKLGEAISTASIRVAARSTVTADL 872
             A N LG   ++A ++V A++ +T  L
Sbjct: 397 CLARNSLGVKNASAELKVLAQTNITTPL 424



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G  V  +C+ +  G+ T  V W+     I         ++    AL +      D+GVYT
Sbjct: 339  GETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396

Query: 1385 CQATNQLGEAVTSCALRVIAKKDL 1408
            C A N LG    S  L+V+A+ ++
Sbjct: 397  CLARNSLGVKNASAELKVLAQTNI 420



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 7/101 (6%)

Query: 3418 KAPVFTVPLSNIENLREGENAHFEARLTPT----DDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            ++ +   P   I    +G+   FE  +T +      P   + WY NG+ + A SR     
Sbjct: 225  RSSILLGPSHQIAVSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSS 284

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
               + IL+   T  EDSG   C A N+ G  +  A +K+ G
Sbjct: 285  SGDYTILQ---TKAEDSGVIQCLASNDAGHVMGRALLKILG 322



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 5/115 (4%)

Query: 1289 QLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFC 1348
            Q+L   +     VR  I +  + Q + +    E      V   CR +  G  T  + W+ 
Sbjct: 212  QILSVQSSSYSSVRSSILLGPSHQIAVSGKGQEVTFECFVTGSCRAR--GTPTPTITWYN 269

Query: 1349 NGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            NG+ +    R   +   DY    +L    EDSGV  C A+N  G  +    L+++
Sbjct: 270  NGRRVFANSRESVSSSGDYT---ILQTKAEDSGVIQCLASNDAGHVMGRALLKIL 321



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 3/63 (4%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            PT  + WY NGR V    R   +    Y    IL   AED+G   C A+N  G  +  + 
Sbjct: 261  PTPTITWYNNGRRVFANSRESVSSSGDYT---ILQTKAEDSGVIQCLASNDAGHVMGRAL 317

Query: 2067 VKV 2069
            +K+
Sbjct: 318  LKI 320



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 7/94 (7%)

Query: 1046 LGPLKGTNKIVEGQSAHFEARV----EPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            LGP        +GQ   FE  V      +   T T+ WY NG+++ + +R        Y 
Sbjct: 230  LGPSHQIAVSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYT 289

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
             L     +AEDSGV   +A N AG     A + +
Sbjct: 290  ILQ---TKAEDSGVIQCLASNDAGHVMGRALLKI 320



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 7/88 (7%)

Query: 2784 VCKEGDNIHFECNVEPS----RDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            V  +G  + FEC V  S      PT  I W+ N + + + +R   +    Y    I  T 
Sbjct: 238  VSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYT---ILQTK 294

Query: 2840 EEDSGIYTCKATNSKGSATTSGSLRCTG 2867
             EDSG+  C A+N  G       L+  G
Sbjct: 295  AEDSGVIQCLASNDAGHVMGRALLKILG 322



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 2/69 (2%)

Query: 4132 CRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGKIEVIXXXXXXXX 4191
            CR  G P P + W  NG  +   SR  ++  G Y   I +T+  D+G I+ +        
Sbjct: 255  CRARGTPTPTITWYNNGRRVFANSRESVSSSGDY--TILQTKAEDSGVIQCLASNDAGHV 312

Query: 4192 XXXXXLKVI 4200
                 LK++
Sbjct: 313  MGRALLKIL 321



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 3/63 (4%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           PT  + WY +GR + A+SR  S+ + G     I+  +AED+G     A N  G  +  A 
Sbjct: 261 PTPTITWYNNGRRVFANSR-ESVSSSG--DYTILQTKAEDSGVIQCLASNDAGHVMGRAL 317

Query: 860 IRV 862
           +++
Sbjct: 318 LKI 320



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 7/87 (8%)

Query: 3843 ESEGVRFECRV----EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAED 3898
            + + V FEC V      +  P   I WY NG+ + +  R  +V   G     IL   AED
Sbjct: 241  KGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSR-ESVSSSG--DYTILQTKAED 297

Query: 3899 SGEYICRAVNDFGEDFTKATISCKKLP 3925
            SG   C A ND G    +A +    +P
Sbjct: 298  SGVIQCLASNDAGHVMGRALLKILGIP 324



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 7/84 (8%)

Query: 3164 GQSAHFECTVVPV----DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
            GQ   FEC V         P   I WY+NG+ +  ++R    S   + +L    T+  DS
Sbjct: 242  GQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDYTILQ---TKAEDS 298

Query: 3220 GEYVCRAYNKYGEDFTRATINCYG 3243
            G   C A N  G    RA +   G
Sbjct: 299  GVIQCLASNDAGHVMGRALLKILG 322



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 2/99 (2%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P ++T     TS+   ET  F+CQ    G+P   V W+     +   +  T  +     A
Sbjct: 324  PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGI 4071
            +        D+G Y C A N  G+    A +K   +  I
Sbjct: 382  LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            PI+ T       +  G+ V  + Q   R +P   + W+K    +   +            
Sbjct: 324  PIWITLPPRDTSVTIGETVVFDCQT--RGNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            L I   +  D+G+YTC A N LG   ++A +K+
Sbjct: 382  LQITGTQRVDNGVYTCLARNSLGVKNASAELKV 414



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 18/74 (24%), Positives = 33/74 (44%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G+ +  + W+     I+ S      +      L+I GT+  D+G Y+C A N  G    S
Sbjct: 350  GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYTCLARNSLGVKNAS 409

Query: 3136 VKLECVDKSKGQKP 3149
             +L+ + ++    P
Sbjct: 410  AELKVLAQTNITTP 423



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 7/73 (9%)

Query: 2390 EGQTAHFDCRLIPV----GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDED 2445
            +GQ   F+C +       G PT  + W+ N + +  +SR + +    Y   TI   + ED
Sbjct: 241  KGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSRESVSSSGDY---TILQTKAED 297

Query: 2446 EGVYMCRASNLLG 2458
             GV  C ASN  G
Sbjct: 298  SGVIQCLASNDAG 310



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 2/84 (2%)

Query: 3710 GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYT 3769
            G  V FDC+    G+PT  + W+         S     +     AL I      D G YT
Sbjct: 339  GETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVYT 396

Query: 3770 CRATNKWGSATTTAKITCSAKRDI 3793
            C A N  G    +A++   A+ +I
Sbjct: 397  CLARNSLGVKNASAELKVLAQTNI 420



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/101 (24%), Positives = 41/101 (40%), Gaps = 2/101 (1%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G P   T  P D  ++   +  F+C+     + +  V W+     +   S     +    
Sbjct: 322  GIPIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSD 379

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI 3655
              L+I G  + D G+YTC A N  G    S +L+V  +  I
Sbjct: 380  GALQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 8/95 (8%)

Query: 4111 PVFVSLPDAVT-VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN----GSRYKLTYDGMY 4165
            P++++LP   T V  GE   F C+  G+P P V W   G+++++     +R+    DG  
Sbjct: 324  PIWITLPPRDTSVTIGETVVFDCQTRGNPTPTVTW-WKGSSVIDISSPSTRFHQKSDGA- 381

Query: 4166 HFDIPKTRQYDTGKIEVIXXXXXXXXXXXXXLKVI 4200
               I  T++ D G    +             LKV+
Sbjct: 382  -LQITGTQRVDNGVYTCLARNSLGVKNASAELKVL 415



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 3435 GENAHFEARLTPTDDPNLKVEWYWNGKS-LKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493
            GE   F+ +      P   V W W G S +   S    F       L+I+ T   D+G Y
Sbjct: 339  GETVVFDCQTRGNPTPT--VTW-WKGSSVIDISSPSTRFHQKSDGALQITGTQRVDNGVY 395

Query: 3494 LCRAYNNYGEAVTTASMKVQGKRNI 3518
             C A N+ G    +A +KV  + NI
Sbjct: 396  TCLARNSLGVKNASAELKVLAQTNI 420



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 4/62 (6%)

Query: 940  TLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            +LR  W KDG  V    R+    N G +A+T  +V   DAG Y C   + +G A+TS  L
Sbjct: 449  SLRFTWTKDGSSV-TDPRMQILAN-GSLAIT--AVHDSDAGTYKCVVSSDVGNASTSTVL 504

Query: 1000 TI 1001
             +
Sbjct: 505  VV 506



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 44/187 (23%), Positives = 70/187 (37%), Gaps = 15/187 (8%)

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA--DEYTLRISEA-FPED 4689
            ++ EG A+ F C   G       W   D           SR    ++  L IS     +D
Sbjct: 34   VIPEGNAVTFYCTASGDLPIQYSWTSADLQNNIRDLTMDSRYTQHNDGRLTISNVQHAKD 93

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT---PLRDIVVYEGQPAQFKTQITS 4746
            +G Y CVA N+ G  T  ++  + +      +PA +   P     +Y           T 
Sbjct: 94   DGYYHCVAKNNEG--TALSRRAIFRVAYL-TIPASSSSPPTASCYMYSHYKYTLGITDTF 150

Query: 4747 KIKPTIQ--WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT-TAAGQVE 4803
             + P  Q  W + GAL+ ET +     +GN   L +     +D G +    T T  G   
Sbjct: 151  PLFPKTQYTWRKSGALLRETDEVSFSSQGN---LYLSRLGFDDIGEYGSEVTNTVTGTSY 207

Query: 4804 TSAKLVV 4810
            +  K ++
Sbjct: 208  SRPKQIL 214



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 5/71 (7%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            CR    P P   + WY NG+ + +  R   S+   +    IL    EDSG   C A N+ 
Sbjct: 255  CRARGTPTPT--ITWYNNGRRVFANSRESVSSSGDYT---ILQTKAEDSGVIQCLASNDA 309

Query: 1926 GQAVSSIRLNV 1936
            G  +    L +
Sbjct: 310  GHVMGRALLKI 320



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 10/99 (10%)

Query: 2902 SVPDTEYPKPEWIIPIAAEHQLV---EGQVLHLE----GQVEPKNDPDLKIEWYFNGKVL 2954
            SV  + Y      I +   HQ+    +GQ +  E    G    +  P   I WY NG+ +
Sbjct: 215  SVQSSSYSSVRSSILLGPSHQIAVSGKGQEVTFECFVTGSCRARGTPTPTITWYNNGRRV 274

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
               SR  ++S   +    ++     DSG+  C A N  G
Sbjct: 275  FANSRESVSSSGDYT---ILQTKAEDSGVIQCLASNDAG 310



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 7/83 (8%)

Query: 2656 EGQHVYLEAQV----EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDD 2711
            +GQ V  E  V      R  P   I W+ NG  +   +R +S    G  T  I   + +D
Sbjct: 241  KGQEVTFECFVTGSCRARGTPTPTITWYNNGRRVFANSR-ESVSSSGDYT--ILQTKAED 297

Query: 2712 SGIYTCKATNLLGEAVSTASIKI 2734
            SG+  C A+N  G  +  A +KI
Sbjct: 298  SGVIQCLASNDAGHVMGRALLKI 320



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G PT  I W  NG+ + A+SR  S+   G     +L    +DSG   C A +  G    +
Sbjct: 259 GTPTPTITWYNNGRRVFANSR-ESVSSSG--DYTILQTKAEDSGVIQCLASNDAGHVMGR 315

Query: 724 AVLHV 728
           A+L +
Sbjct: 316 ALLKI 320



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 4/62 (6%)

Query: 1742 LRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLF 1801
            LR  W ++G  +    R+  + + G +A+    V+  D+GTY C   +++G A TS+ L 
Sbjct: 450  LRFTWTKDGSSV-TDPRMQILAN-GSLAITA--VHDSDAGTYKCVVSSDVGNASTSTVLV 505

Query: 1802 VQ 1803
            VQ
Sbjct: 506  VQ 507



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 10/109 (9%)

Query: 3698 TVEIKDNIDV-PEGGPVHFDCRVEPVGDPTMRIDWF-----HNGRPFATGSRVHTLNDFG 3751
            T   +D++ V PEG  V F C     GD  ++  W      +N R     SR    ND  
Sbjct: 25   TSRARDSVGVIPEGNAVTFYCTAS--GDLPIQYSWTSADLQNNIRDLTMDSRYTQHNDGR 82

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800
                ++ +  A+D G Y C A N  G+A +   I   A   I   S  P
Sbjct: 83   LTISNVQH--AKDDGYYHCVAKNNEGTALSRRAIFRVAYLTIPASSSSP 129



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 3/63 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W  NG  + A++R +      Y  L  K    EDSG   C A N+ G  +  
Sbjct: 259  GTPTPTITWYNNGRRVFANSRESVSSSGDYTILQTK---AEDSGVIQCLASNDAGHVMGR 315

Query: 1798 STL 1800
            + L
Sbjct: 316  ALL 318



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 24/99 (24%), Positives = 40/99 (40%), Gaps = 2/99 (2%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P +IT     T +  G++  F+ +     +P   V W+     +        FH      
Sbjct: 324  PIWITLPPRDTSVTIGETVVFDCQTR--GNPTPTVTWWKGSSVIDISSPSTRFHQKSDGA 381

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENL 3380
            L I      ++G Y C+A N LG  +  A LK  ++ N+
Sbjct: 382  LQITGTQRVDNGVYTCLARNSLGVKNASAELKVLAQTNI 420


>SB_24472| Best HMM Match : I-set (HMM E-Value=0)
          Length = 473

 Score = 96.7 bits (230), Expect = 4e-19
 Identities = 81/303 (26%), Positives = 130/303 (42%), Gaps = 28/303 (9%)

Query: 4513 PPSFTLTAQNVNVT-SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            PP       ++ V+ S ++V    K  GT    + W K+ + +  D R+ ++  DGT  L
Sbjct: 99   PPKIVKFPSSIEVSVSSEVVSFKCKAVGTPAPQISWRKDRQPLPSDGRH-VVRPDGT--L 155

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             IL    +D G YEC+A N AGE   +A    SL        PQ      P   ++ L  
Sbjct: 156  DILRPQVEDEGNYECLARNDAGEQVTEA----SLRYYGRDAVPQ--LTRYPRAQVDTL-- 207

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
                EG ++   C+  G+P PT+ W K G  L     + + +   D Y + ++     D+
Sbjct: 208  ----EGNSVTLQCRAQGRPNPTIAWAKGGTPLDVHDPHMRATSAGDLYIVGVTS---RDD 260

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G Y+C A N AG V+ + +L VT        P  T     V  EG  A  + +      P
Sbjct: 261  GTYRCTASNKAGSVSASTRLVVTAAPYFITRPENT-----VELEGSTASLQCRAGGHPAP 315

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             I W + GA +P      ++  G   +L + ++   D G + C+A    G     + L V
Sbjct: 316  AIAWTKNGARLPSQDRHIVLPSGTLRILYLKHS---DQGQYECQAINVIGVKLARSFLAV 372

Query: 4811 KSK 4813
            +++
Sbjct: 373  RAR 375



 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 78/279 (27%), Positives = 110/279 (39%), Gaps = 32/279 (11%)

Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            E      +    G P P I W +   P+ +  D  +   S   + I+  V   D   +  
Sbjct: 208  EGNSVTLQCRAQGRPNPTIAWAKGGTPL-DVHDPHMRATSAGDLYIVG-VTSRDDGTYRC 265

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543
             A N+ G+   S  LVV             P F    +N     G    L  +  G    
Sbjct: 266  TASNKAGSVSASTRLVVT----------AAPYFITRPENTVELEGSTASLQCRAGGHPAP 315

Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
             + W KNG ++    R+ +L   GT  +L L+    D G+YEC AIN  G      +   
Sbjct: 316  AIAWTKNGARLPSQDRHIVLPS-GTLRILYLKH--SDQGQYECQAINVIG-----VKLAR 367

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
            S  A +         A  PP I +  +D+ V  GQ +   C  VG P P + W K +  +
Sbjct: 368  SFLAVR---------ARVPPSITDKPRDQNVRAGQTVNIFCVAVGAPDPVITWIKDNVQV 418

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
                 F +   AD+ TL I EA   DEG Y+C A NS G
Sbjct: 419  TEGNRFSI---ADDGTLTIREANKGDEGRYQCAARNSVG 454



 Score = 90.6 bits (215), Expect = 3e-17
 Identities = 107/445 (24%), Positives = 160/445 (35%), Gaps = 45/445 (10%)

Query: 4377 EITRKITSTETTEIEHK-AQTQERVVEGPVKPS---KPPIFTKKMQPCRV-FEHEQARFE 4431
            ++ R+  +TET    H+ A+   R +           PP   K      V    E   F+
Sbjct: 62   KLLRRTPNTETAATCHEPAELSGRAIVRLTPRELRCSPPKIVKFPSSIEVSVSSEVVSFK 121

Query: 4432 VEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
             +  G P P I W ++  P+   P    H       L I +  VED   +  +A N  G 
Sbjct: 122  CKAVGTPAPQISWRKDRQPL---PSDGRHVVRPDGTLDILRPQVEDEGNYECLARNDAGE 178

Query: 4492 AKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
                A+L     R  GR   VP         V+   G  V L  +  G     + W K G
Sbjct: 179  QVTEASL-----RYYGRDA-VPQLTRYPRAQVDTLEGNSVTLQCRAQGRPNPTIAWAKGG 232

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
              +  D+ +  +       L I+    +D G Y C A N AG        VV+       
Sbjct: 233  TPL--DVHDPHMRATSAGDLYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVT------- 283

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQ 4670
                     A P  I   ++ +  EG      C+  G P P + W K G +L    ++  
Sbjct: 284  ---------AAPYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIV 334

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RD 4729
            +       TLRI      D+G Y+C A N  G     + L V    +A   P++T   RD
Sbjct: 335  LPSG----TLRILYLKHSDQGQYECQAINVIGVKLARSFLAV----RARVPPSITDKPRD 386

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
              V  GQ             P I W+++   + E   F +  +G    L I    + D G
Sbjct: 387  QNVRAGQTVNIFCVAVGAPDPVITWIKDNVQVTEGNRFSIADDG---TLTIREANKGDEG 443

Query: 4790 TFTCRATTAAGQVETSAKLVVKSKT 4814
             + C A  + G   +   L V+ K+
Sbjct: 444  RYQCAARNSVGVAMSDMILFVQGKS 468



 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 64/207 (30%), Positives = 87/207 (42%), Gaps = 12/207 (5%)

Query: 373 DTQQRETEERIEISEKALAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQ 431
           D  ++ TE  +    +   PQ  +  + + D  EG      CR  GRP P + W      
Sbjct: 175 DAGEQVTEASLRYYGRDAVPQLTRYPRAQVDTLEGNSVTLQCRAQGRPNPTIAWAKGGTP 234

Query: 432 IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
           + D ++  +    +G+  L I  VT  D G   C A NK+G  +   RL V       AP
Sbjct: 235 L-DVHDPHMRATSAGD--LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVV-----TAAP 286

Query: 492 KFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551
            F+ R       EG    L  RA G P P I W K+G   +P+ +  I    G  TL I 
Sbjct: 287 YFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGAR-LPSQDRHIVLPSG--TLRIL 343

Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578
             K SD   Y+C A NV G    R+ L
Sbjct: 344 YLKHSDQGQYECQAINVIGVKLARSFL 370



 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 57/189 (30%), Positives = 87/189 (46%), Gaps = 10/189 (5%)

Query: 392 PQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           P+ VK     +V+   ++  F C+  G P P+++W  + + +  D  H  +V   G   L
Sbjct: 100 PKIVKFPSSIEVSVSSEVVSFKCKAVGTPAPQISWRKDRQPLPSDGRH--VVRPDGT--L 155

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I    + D G   C+ARN +GE   +  L    ++ V       R + ++  EG  V L
Sbjct: 156 DILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYPR-AQVDTLEGNSVTL 214

Query: 511 NARAVGTPTPRITWQKDGVPI-IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
             RA G P P I W K G P+ + +P +R  +   A  L I    + D   Y+CTA N A
Sbjct: 215 QCRAQGRPNPTIAWAKGGTPLDVHDPHMRATS---AGDLYIVGVTSRDDGTYRCTASNKA 271

Query: 570 GSTATRARL 578
           GS +   RL
Sbjct: 272 GSVSASTRL 280



 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 70/278 (25%), Positives = 115/278 (41%), Gaps = 16/278 (5%)

Query: 91  FEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARN 150
           F+ K  G P P +SW + + PL    ++ +R +   G + +L  Q+   DEG Y C ARN
Sbjct: 120 FKCKAVGTPAPQISWRKDRQPLPSDGRHVVRPD---GTLDILRPQVE--DEGNYECLARN 174

Query: 151 QYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYT 210
             GE +    ++  G              R   +T+E  +   Q     Q R    +A+ 
Sbjct: 175 DAGEQVTEASLRYYGRDAVPQLTRYP---RAQVDTLEGNSVTLQ--CRAQGRPNPTIAWA 229

Query: 211 NGTDHSSTDD--FKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKI 268
            G       D   +  +     +  V+ R+  T R    +    S      L   + P  
Sbjct: 230 KGGTPLDVHDPHMRATSAGDLYIVGVTSRDDGTYRCTASNKAG-SVSASTRLVVTAAPYF 288

Query: 269 AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNT 328
             +P N+   EG+ A  Q +  G+P P + W KNG RL + ++H ++ +    TLR+   
Sbjct: 289 ITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIVLPS---GTLRILYL 345

Query: 329 QKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQ 366
           + SD G Y   A N  G  +   +LAV +     + D+
Sbjct: 346 KHSDQGQYECQAINVIGVKLARSFLAVRARVPPSITDK 383



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 59/180 (32%), Positives = 75/180 (41%), Gaps = 10/180 (5%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP F+   ++    EG      CR  G P P + W  N  ++     H +L   SG   L
Sbjct: 285 APYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIVL--PSGT--L 340

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I  +  SD G   C A N  G    +  L V  +   V P   ++    NVR G+ V +
Sbjct: 341 RILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR---VPPSITDKPRDQNVRAGQTVNI 397

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              AVG P P ITW KD V +       I  DG   TL I  A   D   YQC A+N  G
Sbjct: 398 FCVAVGAPDPVITWIKDNVQVTEGNRFSIADDG---TLTIREANKGDEGRYQCAARNSVG 454



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 66/276 (23%), Positives = 107/276 (38%), Gaps = 22/276 (7%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           +G +   + + +G P P ++W +   PL + +   MR     GD  L I  +   D+G Y
Sbjct: 208 EGNSVTLQCRAQGRPNPTIAWAKGGTPL-DVHDPHMRATS-AGD--LYIVGVTSRDDGTY 263

Query: 145 TCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQT 204
            CTA N+ G    S  +                     + +++ +A G            
Sbjct: 264 RCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASLQCRAGG---------HPA 314

Query: 205 QKVAYT-NGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPV 263
             +A+T NG    S D   V       LR +  + S   +Y  ++   I  ++ RS   V
Sbjct: 315 PAIAWTKNGARLPSQDRHIV--LPSGTLRILYLKHSDQGQYECQAINVIGVKLARSFLAV 372

Query: 264 S---PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNH 320
               PP I  KPR+  ++ G          G P P +TW K+  ++   N+  I    + 
Sbjct: 373 RARVPPSITDKPRDQNVRAGQTVNIFCVAVGAPDPVITWIKDNVQVTEGNRFSIA---DD 429

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
            TL +R   K D G Y   A N  G  ++   L V+
Sbjct: 430 GTLTIREANKGDEGRYQCAARNSVGVAMSDMILFVQ 465



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 54/200 (27%), Positives = 78/200 (39%), Gaps = 14/200 (7%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F  + +     E   A  +    G P P I W +    + +     +    T  IL +
Sbjct: 286  PYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIVLPSGTLRILYL 345

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
            +     D   +   A N  G     + L V  +        VPPS T   ++ NV +GQ 
Sbjct: 346  KH---SDQGQYECQAINVIGVKLARSFLAVRAR--------VPPSITDKPRDQNVRAGQT 394

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            V +     G     + W+K+  +V    R  I + DGT T  I EA   D G+Y+C A N
Sbjct: 395  VNIFCVAVGAPDPVITWIKDNVQVTEGNRFSIAD-DGTLT--IREANKGDEGRYQCAARN 451

Query: 4591 SAGEARCDAECVVSLPATKD 4610
            S G A  D    V   +T D
Sbjct: 452  SVGVAMSDMILFVQGKSTTD 471



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 70/277 (25%), Positives = 102/277 (36%), Gaps = 28/277 (10%)

Query: 3027 NLEDSLRKEPGQQPDDDT----GRP--PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSM 3080
            N E   R + G+Q  + +    GR   P+ T   +  VD  EG     +      G  + 
Sbjct: 167  NYECLARNDAGEQVTEASLRYYGRDAVPQLTRYPRAQVDTLEGNSVTLQCRA--QGRPNP 224

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
             I W   G  ++         + G   L I+G  + D GTY C A+NK G    S +L  
Sbjct: 225  TIAWAKGGTPLDVHDPHMRATSAGD--LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVV 282

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
                    P F T  +N   L +G +A  +C       P   I W  NG  +    R   
Sbjct: 283  T-----AAPYFITRPENTVEL-EGSTASLQCRA--GGHPAPAIAWTKNGARLPSQDR-HI 333

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260
            V   G   L I Y ++ D G+Y C+A N  G    R+ +    +       + P    K 
Sbjct: 334  VLPSG--TLRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR-------VPPSITDKP 384

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEG 3297
            R+     G            P   IT I+D  ++ EG
Sbjct: 385  RDQNVRAGQTVNIFCVAVGAPDPVITWIKDNVQVTEG 421



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 87/391 (22%), Positives = 146/391 (37%), Gaps = 25/391 (6%)

Query: 3273 TPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR 3332
            TP      PPK +     +   V  +   F+ + V    P  ++ W  + + LP   R+ 
Sbjct: 91   TPRELRCSPPKIVKFPSSIEVSVSSEVVSFKCKAVGTPAP--QISWRKDRQPLPSDGRHV 148

Query: 3333 TFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEG 3392
               D     LDIL    E+ G YEC+A N  G   T+A+L+   ++ +   ++ PR    
Sbjct: 149  VRPDG---TLDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYPRAQVD 205

Query: 3393 GLE-KLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPN 3451
             LE    TL+     R + ++   KG  P+  V   ++     G+   +   +T  DD  
Sbjct: 206  TLEGNSVTLQCRAQGRPNPTIAWAKGGTPL-DVHDPHMRATSAGD--LYIVGVTSRDDGT 262

Query: 3452 LKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYL-CRAYNNYGEAV--TTA 3508
             +        S+ A +R        F+    +    E S   L CRA  +   A+  T  
Sbjct: 263  YRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKN 322

Query: 3509 SMKVQGK-RNIILES------QLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFT 3561
              ++  + R+I+L S       L    +G  +   A+      +        +  PP  T
Sbjct: 323  GARLPSQDRHIVLPSGTLRILYLKHSDQGQYE-CQAINVIGVKLARSFLAVRARVPPSIT 381

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
              P D  +    + +  C  + V      + W  +   +  G+R    +D    I E   
Sbjct: 382  DKPRDQNVRAGQTVNIFC--VAVGAPDPVITWIKDNVQVTEGNRFSIADDGTLTIREAN- 438

Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
              + D G Y C A N  G A     L V+G+
Sbjct: 439  --KGDEGRYQCAARNSVGVAMSDMILFVQGK 467



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 5/69 (7%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P PV++W +    + E N++S+       D +L I++   GDEG Y C ARN  G A+
Sbjct: 403 GAPDPVITWIKDNVQVTEGNRFSI-----ADDGTLTIREANKGDEGRYQCAARNSVGVAM 457

Query: 157 CSVYIQPEG 165
             + +  +G
Sbjct: 458 SDMILFVQG 466



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 35/93 (37%), Positives = 48/93 (51%), Gaps = 6/93 (6%)

Query: 3828 TPPKFITQIKSHTVE-ESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGF 3886
            +PPK +    S  V   SE V F+C+      P+  I W ++ + LPS  R+  V   G 
Sbjct: 98   SPPKIVKFPSSIEVSVSSEVVSFKCKAVGTPAPQ--ISWRKDRQPLPSDGRH-VVRPDG- 153

Query: 3887 VSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
             +LDIL    ED G Y C A ND GE  T+A++
Sbjct: 154  -TLDILRPQVEDEGNYECLARNDAGEQVTEASL 185



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 5/98 (5%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            +V+  P FIT+ ++    E      +CR      P   I W +NG  LPS  R+  V   
Sbjct: 281  VVTAAPYFITRPENTVELEGSTASLQCRAGGHPAPA--IAWTKNGARLPSQDRH-IVLPS 337

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
            G  +L ILY+   D G+Y C+A+N  G    ++ ++ +
Sbjct: 338  G--TLRILYLKHSDQGQYECQAINVIGVKLARSFLAVR 373



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 52/197 (26%), Positives = 79/197 (40%), Gaps = 15/197 (7%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P F T  ++ V++ EG  A  +      G  +  I W  NG  + +  R   V   G   
Sbjct: 286  PYFITRPENTVEL-EGSTASLQCRA--GGHPAPAIAWTKNGARLPSQDR-HIVLPSG--T 339

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L IL  K +D G Y C+A N  G  +++     V   + + P   T     + ++ GQ+ 
Sbjct: 340  LRILYLKHSDQGQYECQAINVIG-VKLARSFLAV---RARVPPSITDKPRDQNVRAGQTV 395

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
            +  C  V V  PD  I W  +   +    R  +++D G   L I      D G Y C A 
Sbjct: 396  NIFC--VAVGAPDPVITWIKDNVQVTEGNRF-SIADDG--TLTIREANKGDEGRYQCAAR 450

Query: 3228 NKYGEDFTRATINCYGK 3244
            N  G   +   +   GK
Sbjct: 451  NSVGVAMSDMILFVQGK 467



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 6/102 (5%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            + V  AP FIT+     +L EG +A  +CR   +P P   + W  NG  L S  R+    
Sbjct: 280  LVVTAAPYFITRPENTVEL-EGSTASLQCRAGGHPAP--AIAWTKNGARLPSQDRHIVLP 336

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK 1939
                  L IL +   D G+Y C+AIN +G  ++   L V+++
Sbjct: 337  S---GTLRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P  T   +D  V   Q  +     + VG P   + W+++ V +   NR +   D     L
Sbjct: 378  PSITDKPRDQNVRAGQTVNIFC--VAVGAPDPVITWIKDNVQVTEGNRFSIADDG---TL 432

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
             ++  N  D G Y C A N +G A++   LFVQ K++
Sbjct: 433  TIREANKGDEGRYQCAARNSVGVAMSDMILFVQGKST 469



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 80/353 (22%), Positives = 138/353 (39%), Gaps = 35/353 (9%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            ++ W  + +PL S  R     +     LDI+    ED G Y C A N  GE VT      
Sbjct: 131  QISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAGEQVTEASLRY 187

Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQ---DEVITQAPVFT-MPMKDIRVAEN 1725
            + + ++   +++  A  +++ LE  S   +  AQ   +  I  A   T + + D  +   
Sbjct: 188  YGRDAVPQLTRYPRA--QVDTLEGNSVTLQCRAQGRPNPTIAWAKGGTPLDVHDPHMRAT 245

Query: 1726 QAAH-FEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDS-GTY 1783
             A   +   +    D   R         + AS RL       ++      V  E S  + 
Sbjct: 246  SAGDLYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASL 305

Query: 1784 TCRAINELGEAVTSSTLFVQSKASLQLESQH---ESALQKIQQLE--DSSRYQRREDVEV 1838
             CRA      A+     + ++ A L  + +H    S   +I  L+  D  +Y+ +    +
Sbjct: 306  QCRAGGHPAPAIA----WTKNGARLPSQDRHIVLPSGTLRILYLKHSDQGQYECQAINVI 361

Query: 1839 AVNQAPRFIT-QLNGPTKLSE---------GQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
             V  A  F+  +   P  +++         GQ+ +  C     PDP   + W  +   + 
Sbjct: 362  GVKLARSFLAVRARVPPSITDKPRDQNVRAGQTVNIFCVAVGAPDPV--ITWIKDNVQVT 419

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
             G+R+  ++D     L I      D G Y C A N++G A+S + L VQ K +
Sbjct: 420  EGNRFSIADD---GTLTIREANKGDEGRYQCAARNSVGVAMSDMILFVQGKST 469



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 7/110 (6%)

Query: 2791 IHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKA 2850
            + F+C    +  P  +I W  + +PLPS  R+    D +   LDI     ED G Y C A
Sbjct: 118  VSFKCKAVGT--PAPQISWRKDRQPLPSDGRHVVRPDGT---LDILRPQVEDEGNYECLA 172

Query: 2851 TNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAG-LEAVEQAEEARLAKGR 2899
             N  G   T  SLR  G   +   T++P+ +   LE      + R A+GR
Sbjct: 173  RNDAGEQVTEASLRYYGRDAVPQLTRYPRAQVDTLEGNSVTLQCR-AQGR 221



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 5/99 (5%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            P+      +IE     +   F+C  V    P  +I W  + QP+    R   V   G   
Sbjct: 100  PKIVKFPSSIEVSVSSEVVSFKCKAVGTPAP--QISWRKDRQPLPSDGR-HVVRPDG--T 154

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGV 3247
            LDI   Q  D G Y C A N  GE  T A++  YG+  V
Sbjct: 155  LDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAV 193



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 13/138 (9%)

Query: 2885 EAVEQAEEARLAKGRRPSVPD-TEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDL 2943
            +A EQ  EA L    R +VP  T YP+        A+   +EG  + L+ + + + +P  
Sbjct: 175  DAGEQVTEASLRYYGRDAVPQLTRYPR--------AQVDTLEGNSVTLQCRAQGRPNPT- 225

Query: 2944 KIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYC 3003
             I W   G  L+        +  G   L +V V  RD G Y C A NK G    S+ +  
Sbjct: 226  -IAWAKGGTPLDVHDPHMRATSAG--DLYIVGVTSRDDGTYRCTASNKAGSVSASTRLVV 282

Query: 3004 TSKDNLIERTQHPKGTEG 3021
            T+    I R ++    EG
Sbjct: 283  TAAPYFITRPENTVELEG 300



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 39/148 (26%), Positives = 65/148 (43%), Gaps = 14/148 (9%)

Query: 3548 LTPEAESGNPPEFTTTPSDLILSENSSA-HFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            LTP     +PP+    PS + +S +S    F+C+   V   + ++ W  + +PL +  R 
Sbjct: 90   LTPRELRCSPPKIVKFPSSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGR- 146

Query: 3607 KTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFK 3666
              +   G   L+I      D G Y C A N  GE      L+  GR  +   PQL  + +
Sbjct: 147  HVVRPDG--TLDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAV---PQLTRYPR 201

Query: 3667 SGTESIQKLEETLHKREEITIEDEKPNP 3694
            +  ++++    TL  R +      +PNP
Sbjct: 202  AQVDTLEGNSVTLQCRAQ-----GRPNP 224



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 6/113 (5%)

Query: 1307 VMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD 1366
            V Q  ++ RA   ++T+EG +V L+CR Q  G     + W   G P+        A    
Sbjct: 193  VPQLTRYPRA--QVDTLEGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG 248

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLE 1419
               L ++ V   D G Y C A+N+ G    S  L V A    I   ++   LE
Sbjct: 249  --DLYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 5/95 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P FI   ++   +EG     + R    G P   I W KNG  + +  R   +   G  +L
Sbjct: 286 PYFITRPENTVELEGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDRHI-VLPSG--TL 340

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
            +L L   D G+Y C+A++  GV   ++ L V  R
Sbjct: 341 RILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/110 (24%), Positives = 45/110 (40%), Gaps = 4/110 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+    P++  + +EG  V  +C+ +     N  + W K G P+ +          G   
Sbjct: 194  PQLTRYPRAQVDTLEGNSVTLQCRAQG--RPNPTIAWAKGGTPLDVHDPHMRATSAG--D 249

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLE 1553
            L I+ + + D G Y C A N  G+   S RL   +    +   +N   LE
Sbjct: 250  LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 4/95 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+ T   +  +D  EG  V   CR +  G P   I W   G P             G   
Sbjct: 194  PQLTRYPRAQVDTLEGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--D 249

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSA 3789
            L I  + +RD G Y C A+NK GS + + ++  +A
Sbjct: 250  LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTA 284



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 31/125 (24%), Positives = 48/125 (38%), Gaps = 8/125 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L+IL  +  D G Y C A N  G+      L      +   P+ T + +      +G S 
Sbjct: 155  LDILRPQVEDEGNYECLARNDAGEQVTEASLRYY--GRDAVPQLTRYPRAQVDTLEGNSV 212

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMR-HSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
              +C       P+  I W   G P+  H   ++  S     ++ +    + D G Y C A
Sbjct: 213  TLQCRA--QGRPNPTIAWAKGGTPLDVHDPHMRATSAGDLYIVGVT---SRDDGTYRCTA 267

Query: 3227 YNKYG 3231
             NK G
Sbjct: 268  SNKAG 272



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 5/99 (5%)

Query: 2116 TSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
            +S+E     +   F+C+   +  P   I W  + Q + +  R+    D     LDIL   
Sbjct: 107  SSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQ 161

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHP 2214
             ED G Y C A N  GE V   +L+  G   +   T++P
Sbjct: 162  VEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYP 200



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 32/117 (27%), Positives = 46/117 (39%), Gaps = 5/117 (4%)

Query: 3558 PEFTTTP-SDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            P+ T  P + +   E +S   +CR       +  + W   G PL            G   
Sbjct: 194  PQLTRYPRAQVDTLEGNSVTLQCRA--QGRPNPTIAWAKGGTPLDVHDPHMRATSAGD-- 249

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQ 3673
            L I GV  RD G Y C A+N+ G  + S +L V      I  P+     +  T S+Q
Sbjct: 250  LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASLQ 306



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 4/106 (3%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP+ +    S+      ++    + + VG P  +I W K+ Q + +  R   +   G  +
Sbjct: 99  PPKIVKFPSSIEVSVSSEV-VSFKCKAVGTPAPQISWRKDRQPLPSDGRHV-VRPDG--T 154

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHP 741
           LD+L   ++D G Y C A +  G   T+A L    R  + + +++P
Sbjct: 155 LDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYP 200



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 797 VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
           V  P  ++ W KD +P+ +  R   +   G  +L+I+  + ED G+Y   A N  GE ++
Sbjct: 125 VGTPAPQISWRKDRQPLPSDGRHV-VRPDG--TLDILRPQVEDEGNYECLARNDAGEQVT 181

Query: 857 TASIRVAARSTV 868
            AS+R   R  V
Sbjct: 182 EASLRYYGRDAV 193



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 16/47 (34%), Positives = 23/47 (48%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRY 4157
            P F++ P+     EG  A   CR  GHP P + W  NG  + +  R+
Sbjct: 286  PYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRH 332



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 5/72 (6%)

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
            N++ GQT +  C  + VG P   + W ++   + + +R +   D    ++TI      DE
Sbjct: 388  NVRAGQTVNIFC--VAVGAPDPVITWIKDNVQVTEGNRFSIADDG---TLTIREANKGDE 442

Query: 2447 GVYMCRASNLLG 2458
            G Y C A N +G
Sbjct: 443  GRYQCAARNSVG 454



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 16/58 (27%), Positives = 25/58 (43%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDG 4163
            +AR PP     P    V  G+     C   G P P + W+ +   +  G+R+ +  DG
Sbjct: 373  RARVPPSITDKPRDQNVRAGQTVNIFCVAVGAPDPVITWIKDNVQVTEGNRFSIADDG 430



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAET 722
           VG P   I W+K+   +   +RF SI   G  +L +   N  D G Y C A ++ GVA +
Sbjct: 402 VGAPDPVITWIKDNVQVTEGNRF-SIADDG--TLTIREANKGDEGRYQCAARNSVGVAMS 458

Query: 723 KAVLHVTPRATIERT 737
             +L V  ++T + T
Sbjct: 459 DMILFVQGKSTTDFT 473



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 7/102 (6%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPV-HFDCRVEPVGDPTMRIDWFHNGRPFATGSR 3743
            +T  + + +PP+  V+   +I+V     V  F C+   VG P  +I W  + +P  +  R
Sbjct: 90   LTPRELRCSPPKI-VKFPSSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGR 146

Query: 3744 VHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
             H +   G   LDI      D G Y C A N  G   T A +
Sbjct: 147  -HVVRPDG--TLDILRPQVEDEGNYECLARNDAGEQVTEASL 185



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 4/96 (4%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            EG S   +CR +  P+P   + W   G  L     +  +   G   L I+ V   D G Y
Sbjct: 208  EGNSVTLQCRAQGRPNPT--IAWAKGGTPLDVHDPHMRATSAG--DLYIVGVTSRDDGTY 263

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
             C A N  G   +S RL V +    I   ++   LE
Sbjct: 264  RCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 4108 RC-PPVFVSLPDAVTVE-EGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMY 4165
            RC PP  V  P ++ V    E   F C+  G P P++ W  +   + +  R+ +  DG  
Sbjct: 96   RCSPPKIVKFPSSIEVSVSSEVVSFKCKAVGTPAPQISWRKDRQPLPSDGRHVVRPDGT- 154

Query: 4166 HFDIPKTRQYDTGKIEVI 4183
              DI + +  D G  E +
Sbjct: 155  -LDILRPQVEDEGNYECL 171



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 2004 VNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVT 2063
            V  P  ++ W  + +P+    R     D     LDIL    ED G Y C A N  GE VT
Sbjct: 125  VGTPAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAGEQVT 181

Query: 2064 TSSVK 2068
             +S++
Sbjct: 182  EASLR 186



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 3/66 (4%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P+  I W K+ V +T G R  S  D G  TL+I      D G Y C A N +G A+S   
Sbjct: 405  PDPVITWIKDNVQVTEGNRF-SIADDG--TLTIREANKGDEGRYQCAARNSVGVAMSDMI 461

Query: 2732 IKIEDR 2737
            + ++ +
Sbjct: 462  LFVQGK 467



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 5/83 (6%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P+ V  P SIE  +  + V F+CK   V     ++ W K+ QP+    R   +   G   
Sbjct: 100  PKIVKFPSSIEVSVSSEVVSFKCK--AVGTPAPQISWRKDRQPLPSDGR-HVVRPDG--T 154

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVG 1526
            LDI+    ED G Y C A N  G
Sbjct: 155  LDILRPQVEDEGNYECLARNDAG 177



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 7/99 (7%)

Query: 1864 YECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923
            ++C+    P P  ++ W  + + L S  R+    D     LDIL    ED G Y C A N
Sbjct: 120  FKCKAVGTPAP--QISWRKDRQPLPSDGRHVVRPD---GTLDILRPQVEDEGNYECLARN 174

Query: 1924 NLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDS 1962
            + G+ V+   L    ++++ + +++  A  ++  LE +S
Sbjct: 175  DAGEQVTEASLRYYGRDAVPQLTRYPRA--QVDTLEGNS 211



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            VG P  ++ W ++  P+ +  R     D     L++     ED G Y C A N+ GE VT
Sbjct: 125  VGTPAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAGEQVT 181

Query: 1797 SSTL 1800
             ++L
Sbjct: 182  EASL 185



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 8/115 (6%)

Query: 2625 AMNKVPEMFVDTG--VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNG 2682
            A NK   +   T   V  AP F T  ++  +L EG    L+ +      P   I W KNG
Sbjct: 267  ASNKAGSVSASTRLVVTAAPYFITRPENTVEL-EGSTASLQCRAGGHPAP--AIAWTKNG 323

Query: 2683 VTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
              L +  R       G  TL I  L++ D G Y C+A N++G  ++ + + +  R
Sbjct: 324  ARLPSQDR-HIVLPSG--TLRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 9/103 (8%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGK--PIKTGHRFRPA 1362
            + V  AP F     N   +EG+   L+CR    G     + W  NG   P +  H   P+
Sbjct: 280  LVVTAAPYFITRPENTVELEGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDRHIVLPS 337

Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
                   L +L +   D G Y CQA N +G  +    L V A+
Sbjct: 338  G-----TLRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 10/108 (9%)

Query: 1311 PQFSRALHNIE-TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTG--HRFRPAYEFDY 1367
            P+  +   +IE +V    V  +C+   VG    ++ W  + +P+ +   H  RP      
Sbjct: 100  PKIVKFPSSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGRHVVRPDG---- 153

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHP 1415
              LD+L    ED G Y C A N  GE VT  +LR   +  +   +++P
Sbjct: 154  -TLDILRPQVEDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYP 200



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 4/96 (4%)

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
            EG ++ L+CR +  G P   + W   G  + V          G   L I+  TS D G Y
Sbjct: 208  EGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--DLYIVGVTSRDDGTY 263

Query: 1251 TVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286
               A N  GS   S  + V      +T  +N   +E
Sbjct: 264  RCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 6/83 (7%)

Query: 2242 PRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            P F+T    T  + EG TA  +C+      P   I +  NG  L S  R HI    G  +
Sbjct: 286  PYFITRPENTVEL-EGSTASLQCRAGG--HPAPAIAWTKNGARLPSQDR-HIVLPSG--T 339

Query: 2302 LDIQHCVPEDAGEYSVKAINALG 2324
            L I +    D G+Y  +AIN +G
Sbjct: 340  LRILYLKHSDQGQYECQAINVIG 362



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 6/92 (6%)

Query: 1982 KPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILY 2041
            KP ++  V  G  V++        DP   + W  +   V +G+RF    D     L I  
Sbjct: 383  KP-RDQNVRAGQTVNIFCVAVGAPDPV--ITWIKDNVQVTEGNRFSIADDG---TLTIRE 436

Query: 2042 AYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
            A   D G Y C A N+VG A++   + V  KS
Sbjct: 437  ANKGDEGRYQCAARNSVGVAMSDMILFVQGKS 468



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 7/121 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG+++  +C  +   +PT  I W     PL     +      S   L I      D G Y
Sbjct: 208  EGNSVTLQCRAQGRPNPT--IAWAKGGTPLDVHDPHMRAT--SAGDLYIVGVTSRDDGTY 263

Query: 2847 TCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDT 2906
             C A+N  GS + S  L  T     YF T+ P+    LE    + + R      P++  T
Sbjct: 264  RCTASNKAGSVSASTRLVVTAAP--YFITR-PENTVELEGSTASLQCRAGGHPAPAIAWT 320

Query: 2907 E 2907
            +
Sbjct: 321  K 321



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 6/96 (6%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P FI   ++  EL EG  A  + +      P   + W K+G  + +  R   +   G  +
Sbjct: 286 PYFITRPENTVEL-EGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDRHI-VLPSG--T 339

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           L I++L+  D G Y  +A+N +G  ++ + + V AR
Sbjct: 340 LRILYLKHSDQGQYECQAINVIGVKLARSFLAVRAR 375



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 5/85 (5%)

Query: 2119 ENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAED 2178
            +N++ G   +  C      DP +T  W  +  ++  G+R+    D     L I      D
Sbjct: 387  QNVRAGQTVNIFCVAVGAPDPVIT--WIKDNVQVTEGNRFSIADDG---TLTIREANKGD 441

Query: 2179 SGTYMCKATNKLGEAVNTCTLKVAG 2203
             G Y C A N +G A++   L V G
Sbjct: 442  EGRYQCAARNSVGVAMSDMILFVQG 466



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 5/108 (4%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP+ V    S    V  E   F+C+   VG P  ++ W  + +PL    R     D G +
Sbjct: 99   PPKIVKFPSSIEVSVSSEVVSFKCKA--VGTPAPQISWRKDRQPLPSDGRHVVRPD-GTL 155

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPK 4079
             +    V  ED G Y C A N  G   T+A ++  G+  +   ++ P+
Sbjct: 156  DILRPQV--EDEGNYECLARNDAGEQVTEASLRYYGRDAVPQLTRYPR 201



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 4/110 (3%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+     + Q+   EG     + R +  G     + W K G P++         + G   
Sbjct: 194  PQLTRYPRAQVDTLEGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--D 249

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLE 1018
            L I  VT  D G Y C A N  G  + S  L +      I   ++   LE
Sbjct: 250  LYIVGVTSRDDGTYRCTASNKAGSVSASTRLVVTAAPYFITRPENTVELE 299



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+T   +   L EG  A  +CR      P   I W  NG ++ +  R+          
Sbjct: 286  PYFITRPENTVEL-EGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDRHIVLPSG---T 339

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            L ILY    D G Y C+A N +G
Sbjct: 340  LRILYLKHSDQGQYECQAINVIG 362



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 6/87 (6%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            VT  P F+TRP++    +EG     +C+          + W KNG  +    R   +   
Sbjct: 282  VTAAPYFITRPENTVE-LEGSTASLQCRAGGHPAP--AIAWTKNGARLPSQDRHIVLPSG 338

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVG 1526
                L I+ L   D G Y C+A+N++G
Sbjct: 339  ---TLRILYLKHSDQGQYECQAINVIG 362



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 5/90 (5%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F    +N    +G  A  + +  G+P P ++WT+  A L   +++ +     +G  +L
Sbjct: 286 PYFITRPENTVELEGSTASLQCRAGGHPAPAIAWTKNGARLPSQDRHIVL---PSG--TL 340

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
            I  +   D+G+Y C A N  G  +   ++
Sbjct: 341 RILYLKHSDQGQYECQAINVIGVKLARSFL 370



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 6/99 (6%)

Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT-GARLKSTF 2695
            G    P  T + ++    +EG  V L+ + + R  PN  I W K G  L      +++T 
Sbjct: 189  GRDAVPQLTRYPRAQVDTLEGNSVTLQCRAQGR--PNPTIAWAKGGTPLDVHDPHMRATS 246

Query: 2696 DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
               L  + + S    D G Y C A+N  G   ++  + +
Sbjct: 247  AGDLYIVGVTSR---DDGTYRCTASNKAGSVSASTRLVV 282



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 30/109 (27%), Positives = 41/109 (37%), Gaps = 7/109 (6%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG+    +CR +    P+ TI W   G  +     +      G   L I+   + D GTY
Sbjct: 208  EGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--DLYIVGVTSRDDGTY 263

Query: 2183 MCKATNKLGEAVNTCTLKVAGHRNIIL---DTQHPNGLEKIRQLEAQGH 2228
             C A+NK G    +  L V      I    +T    G     Q  A GH
Sbjct: 264  RCTASNKAGSVSASTRLVVTAAPYFITRPENTVELEGSTASLQCRAGGH 312



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 3/77 (3%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  +I W  + + L    R  +  D    TLD++     D G Y C A N  GE  T ++
Sbjct: 128  PAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAGEQVTEAS 184

Query: 3001 VYCTSKDNLIERTQHPK 3017
            +    +D + + T++P+
Sbjct: 185  LRYYGRDAVPQLTRYPR 201



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            PD  I W  +   + +G+RF +  D    TL + +  + D G Y C A N  G A +   
Sbjct: 405  PDPVITWIKDNVQVTEGNRFSIADDG---TLTIREANKGDEGRYQCAARNSVGVAMSDMI 461

Query: 3001 VYCTSK 3006
            ++   K
Sbjct: 462  LFVQGK 467



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F    ++ +++ EG      CR    G P   I W  NG    +  R H +   G   
Sbjct: 286  PYFITRPENTVEL-EGSTASLQCRAG--GHPAPAIAWTKNGARLPSQDR-HIVLPSG--T 339

Query: 3755 LDIDYIYARDAGEYTCRATNKWG 3777
            L I Y+   D G+Y C+A N  G
Sbjct: 340  LRILYLKHSDQGQYECQAINVIG 362



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVAL 1637
            P  T   ++  ++ GQ  +     +   D    + W  +N  +  G+RF+  ++     L
Sbjct: 378  PSITDKPRDQNVRAGQTVNIFCVAVGAPDPV--ITWIKDNVQVTEGNRFSIADDG---TL 432

Query: 1638 DIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKS 1674
             I      D G Y C A N++G A++  I  V  K +
Sbjct: 433  TIREANKGDEGRYQCAARNSVGVAMSDMILFVQGKST 469



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V  G+ +++ C    +G P   + W  +   VT G+RF +  D G   L I  A   D G
Sbjct: 389  VRAGQTVNIFC--VAVGAPDPVITWIKDNVQVTEGNRF-SIADDG--TLTIREANKGDEG 443

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERS 1273
             Y   A N +G A +  I+ V  +S
Sbjct: 444  RYQCAARNSVGVAMSDMILFVQGKS 468



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 932  RLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            + + +G    ++ W KD +P+ +  R     +     L I    V D G+Y C A N  G
Sbjct: 121  KCKAVGTPAPQISWRKDRQPLPSDGRHVVRPDG---TLDILRPQVEDEGNYECLARNDAG 177

Query: 992  QATTSANLTIVTKKDIIAESQHP 1014
            +  T A+L    +  +   +++P
Sbjct: 178  EQVTEASLRYYGRDAVPQLTRYP 200



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 4/88 (4%)

Query: 642 PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSL 701
           P   V  +EG  +  + R +  G P   I W K G  ++           G   L ++ +
Sbjct: 200 PRAQVDTLEGNSVTLQCRAQ--GRPNPTIAWAKGGTPLDVHDPHMRATSAG--DLYIVGV 255

Query: 702 NIQDSGEYTCRAVSATGVAETKAVLHVT 729
             +D G Y C A +  G       L VT
Sbjct: 256 TSRDDGTYRCTASNKAGSVSASTRLVVT 283



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 8/89 (8%)

Query: 2371 VTRQRPVF-TQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTH 2429
            V    P F T+P   ++   EG TA   CR    G P   + W +N   +    R     
Sbjct: 281  VVTAAPYFITRPENTVE--LEGSTASLQCRA--GGHPAPAIAWTKNGARLPSQDRHIVLP 336

Query: 2430 DFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
                 ++ I +++  D+G Y C+A N++G
Sbjct: 337  SG---TLRILYLKHSDQGQYECQAINVIG 362



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 24/88 (27%), Positives = 34/88 (38%), Gaps = 5/88 (5%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845
            + G  ++  C    + DP   I W  +N  +  G R+    D +   L I    + D G 
Sbjct: 390  RAGQTVNIFCVAVGAPDPV--ITWIKDNVQVTEGNRFSIADDGT---LTIREANKGDEGR 444

Query: 2846 YTCKATNSKGSATTSGSLRCTGDKNIYF 2873
            Y C A NS G A +   L   G     F
Sbjct: 445  YQCAARNSVGVAMSDMILFVQGKSTTDF 472



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 3/58 (5%)

Query: 2533 VPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            V VG P     W  + V++  G+RF    D    TL I      D G Y C A N  G
Sbjct: 400  VAVGAPDPVITWIKDNVQVTEGNRFSIADD---GTLTIREANKGDEGRYQCAARNSVG 454


>SB_33342| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1189

 Score = 96.3 bits (229), Expect = 5e-19
 Identities = 100/408 (24%), Positives = 159/408 (38%), Gaps = 30/408 (7%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F ++     V ++ QA  +    G P P I W      +  + D +       S+L I
Sbjct: 84   PFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKILPDGSLLFI 143

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSAN-LVVEEKRRQGRGGIVPPSFTLTAQNVN--VTS 4527
                +E +        N    A    N L  E + R  +  +   S  +T + V   V  
Sbjct: 144  T---IEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGLSSKITIEPVTSQVIF 200

Query: 4528 GQLVRLDTKVTGTKPIDVY-WL---KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
            G + RL  KV  + P  +  W    K+G ++     +K+    G   + I      D G+
Sbjct: 201  GDVARLFCKVRHSLPDSIIQWKFKQKDGSEIALTPSSKVTLLPGG-VIQIRNVQLDDGGE 259

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y+C A N   + R  +    +L    D+  P+         ++ P    +  +G+     
Sbjct: 260  YKCTAENPVTK-RTHSSAYATLTVIPDRGNPRRADF-----VVTPPSRVVAIKGKHTVLE 313

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C + G P P V+WYK  +++    Y        E  L I +  P D G YKC A +S  +
Sbjct: 314  CAVKGSPKPVVKWYKNGQIVT---YDSRVTIIGESNLEIMQVVPSDAGTYKCEATSSGSQ 370

Query: 4704 -VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
             V+   +LKV  P        +  LRD   Y G    F        KP + W + G  I 
Sbjct: 371  PVSAETRLKVNYPPVF-----IKRLRDHNAYTGSVVTFNCTADGNPKPNVYWSKNGYKIG 425

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             T DF  + +G    L + +    D G + C AT + G ++ SA+L V
Sbjct: 426  ST-DFTKVGDG---FLKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469



 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 53/175 (30%), Positives = 71/175 (40%), Gaps = 14/175 (8%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +GK T  +C V G P P V W+ N + +  D    I+    G   L I  V  SD+G   
Sbjct: 306 KGKHTVLECAVKGSPKPVVKWYKNGQIVTYDSRVTII----GESNLEIMQVVPSDAGTYK 361

Query: 465 CVARNKSGE-TAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
           C A +   +  + + RL V        P F++R    N   G  V  N  A G P P + 
Sbjct: 362 CEATSSGSQPVSAETRLKVN-----YPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVY 416

Query: 524 WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           W K+G  I      ++    G   L +     SD   YQC A N  GS    A L
Sbjct: 417 WSKNGYKIGSTDFTKV----GDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAEL 467



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 50/192 (26%), Positives = 79/192 (41%), Gaps = 9/192 (4%)

Query: 384 EISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI--NDRQIRDDYNHKIL 441
           EI+   LAP F++   D  V + +     CR  G P P ++W    ND  +  D   KIL
Sbjct: 76  EITSSQLAPFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKIL 135

Query: 442 VNESGNH-ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV-VAPKFVERFST 499
            + S     +  T  +  D G   CVA ++     ++ R  +++ +   ++ K      T
Sbjct: 136 PDGSLLFITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGLSSKITIEPVT 195

Query: 500 LNVREGEPVVLNARA-VGTPTPRITW---QKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
             V  G+   L  +     P   I W   QKDG  I   P  ++    G   + I   + 
Sbjct: 196 SQVIFGDVARLFCKVRHSLPDSIIQWKFKQKDGSEIALTPSSKVTLLPG-GVIQIRNVQL 254

Query: 556 SDAAWYQCTAQN 567
            D   Y+CTA+N
Sbjct: 255 DDGGEYKCTAEN 266



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 62/244 (25%), Positives = 95/244 (38%), Gaps = 18/244 (7%)

Query: 3040 PDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRT 3099
            PD    R  +F       V   +G+    E ++   G    V++W+ NG+ +    R+  
Sbjct: 284  PDRGNPRRADFVVTPPSRVVAIKGKHTVLECAV--KGSPKPVVKWYKNGQIVTYDSRVTI 341

Query: 3100 VYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE 3159
            +   G   LEI+    +D+GTY C AT+  G   +S +           P F   +++  
Sbjct: 342  I---GESNLEIMQVVPSDAGTYKCEATSS-GSQPVSAETRL---KVNYPPVFIKRLRD-H 393

Query: 3160 GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
                G    F CT     +P   + W  NG  +  ST    V D GF  L +      D 
Sbjct: 394  NAYTGSVVTFNCTA--DGNPKPNVYWSKNGYKI-GSTDFTKVGD-GF--LKVEDLLPSDM 447

Query: 3220 GEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA 3279
            G Y C A N  G     A ++ Y K GV L + +  + A+      L      TP   + 
Sbjct: 448  GMYQCFATNSLGSIQASAELSVY-KTGVPLPTTRLPTTAQ-TPTTILPPTTTPTPPPTTT 505

Query: 3280 EPPK 3283
            EP +
Sbjct: 506  EPQR 509



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 57/243 (23%), Positives = 92/243 (37%), Gaps = 41/243 (16%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           +TKR    +   ++   DR   P     +   P      +G     +  + G+P+P V W
Sbjct: 268 VTKRTHSSAYATLTVIPDRG-NPRRADFVVTPPSRVVAIKGKHTVLECAVKGSPKPVVKW 326

Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPT 359
           +KNGQ +   ++  II   N   L +     SD+G Y         C  TS         
Sbjct: 327 YKNGQIVTYDSRVTIIGESN---LEIMQVVPSDAGTYK--------CEATS--------- 366

Query: 360 ESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRP 419
                       + +Q    E R++++     P F+K  +D +   G +  F+C   G P
Sbjct: 367 ------------SGSQPVSAETRLKVN---YPPVFIKRLRDHNAYTGSVVTFNCTADGNP 411

Query: 420 YPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCR 479
            P V W  N  +I      K+     G+  L + ++  SD G+  C A N  G       
Sbjct: 412 KPNVYWSKNGYKIGSTDFTKV-----GDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAE 466

Query: 480 LNV 482
           L+V
Sbjct: 467 LSV 469



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 6/103 (5%)

Query: 470 KSGETAFQCR-LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
           + GE + + + +N I   Q+ AP F+E  S + V++    +L  RA G P+PRI+W+ +G
Sbjct: 63  EKGEISLRGKYVNEITSSQL-APFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNG 121

Query: 529 --VPIIPNPELRIHTDGGASTLDIPRAKAS--DAAWYQCTAQN 567
             + +  +   +I  DG    + I   K+S  D   YQC A +
Sbjct: 122 NDLNLAGDKRRKILPDGSLLFITIEHTKSSKPDEGNYQCVASS 164



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 13/112 (11%)

Query: 3820 PKEEPIVSTPPKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRY 3878
            P+    V TPP  +  IK  HTV        EC V  K  PK  ++WY+NG+++    R 
Sbjct: 289  PRRADFVVTPPSRVVAIKGKHTV-------LECAV--KGSPKPVVKWYKNGQIVTYDSR- 338

Query: 3879 RTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
              V  +G  +L+I+ V   D+G Y C A +   +  +  T      P + ++
Sbjct: 339  --VTIIGESNLEIMQVVPSDAGTYKCEATSSGSQPVSAETRLKVNYPPVFIK 388



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 6/99 (6%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            T I D     +  FV  P S    I+G+H   EC ++        V+W+KNGQ VT   R
Sbjct: 281  TVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAVKG--SPKPVVKWYKNGQIVTYDSR 338

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
               I   G   L+I+ ++  D+G Y C A +  G+  VS
Sbjct: 339  VTII---GESNLEIMQVVPSDAGTYKCEATS-SGSQPVS 373



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 38/127 (29%), Positives = 57/127 (44%), Gaps = 9/127 (7%)

Query: 3541 YSGTVDTLTPEAESGNP--PEFTTTP-SDLILSENSSAHFECRLIPVNDSSMRVEWFHNG 3597
            +S    TLT   + GNP   +F  TP S ++  +      EC +         V+W+ NG
Sbjct: 273  HSSAYATLTVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAV--KGSPKPVVKWYKNG 330

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
            + +   SRV  I +     LEI  V   DAG Y C+AT+  G   VS + ++K     + 
Sbjct: 331  QIVTYDSRVTIIGESN---LEIMQVVPSDAGTYKCEATS-SGSQPVSAETRLKVNYPPVF 386

Query: 3658 EPQLPSH 3664
              +L  H
Sbjct: 387  IKRLRDH 393



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 6/144 (4%)

Query: 3780 TTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSH 3839
            T  +++T   + ++ +   +P      K +    G    + +    V+ PP FI +++ H
Sbjct: 334  TYDSRVTIIGESNLEIMQVVPSDAGTYKCEATSSGSQPVSAETRLKVNYPPVFIKRLRDH 393

Query: 3840 TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899
                   V F C  +   +PK  + W +NG  + S   +  V D GF+ ++ L     D 
Sbjct: 394  NAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKIGSTD-FTKVGD-GFLKVEDL--LPSDM 447

Query: 3900 GEYICRAVNDFGEDFTKATISCKK 3923
            G Y C A N  G     A +S  K
Sbjct: 448  GMYQCFATNSLGSIQASAELSVYK 471



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 31/104 (29%), Positives = 50/104 (48%), Gaps = 9/104 (8%)

Query: 640 IVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDML 699
           + P   V A++G     E  ++  G P   ++W KNGQ +   SR T I   G  +L+++
Sbjct: 296 VTPPSRVVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTII---GESNLEIM 350

Query: 700 SLNIQDSGEYTCRAVSATG---VAETKAVLHVTPRATIERTSQH 740
            +   D+G Y C A S+      AET+  ++  P   I+R   H
Sbjct: 351 QVVPSDAGTYKCEATSSGSQPVSAETRLKVNYPP-VFIKRLRDH 393



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 41/147 (27%), Positives = 67/147 (45%), Gaps = 14/147 (9%)

Query: 3642 TVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDE-KPN-PPRFTV 3699
            T   ++ + G   + +   +PS   +GT    K E T    + ++ E   K N PP F  
Sbjct: 334  TYDSRVTIIGESNLEIMQVVPSD--AGT---YKCEATSSGSQPVSAETRLKVNYPPVFIK 388

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
             ++D+ +   G  V F+C  +  G+P   + W  NG  +  GS   T    GF  L ++ 
Sbjct: 389  RLRDH-NAYTGSVVTFNCTAD--GNPKPNVYWSKNG--YKIGSTDFTKVGDGF--LKVED 441

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKIT 3786
            +   D G Y C ATN  GS   +A+++
Sbjct: 442  LLPSDMGMYQCFATNSLGSIQASAELS 468



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 34/114 (29%), Positives = 51/114 (44%), Gaps = 6/114 (5%)

Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
           +V  PP FI  L+   A  G  + F    +  G+P   + W KNG  I  S+ FT +   
Sbjct: 379 KVNYPPVFIKRLRDHNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI-GSTDFTKVGD- 434

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQ 745
           G++ ++   L   D G Y C A ++ G  +  A L V        T++ P T Q
Sbjct: 435 GFLKVE--DLLPSDMGMYQCFATNSLGSIQASAELSVYKTGVPLPTTRLPTTAQ 486



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 5/102 (4%)

Query: 3951 KKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWF 4010
            K+  S  Y T   + D    +   FV    S+   ++ + T  EC  A  G P   V+W+
Sbjct: 270  KRTHSSAYATLTVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLEC--AVKGSPKPVVKWY 327

Query: 4011 FNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATN 4052
             NG+ + + +R T I +     M    V P D+G Y C AT+
Sbjct: 328  KNGQIVTYDSRVTIIGESNLEIMQ---VVPSDAGTYKCEATS 366



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 2/69 (2%)

Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN--TIVNGSRYK 4158
            V E + ++  P F+  P  + V++   A   CR  G P PR+ W  NGN   +    R K
Sbjct: 74   VNEITSSQLAPFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRK 133

Query: 4159 LTYDGMYHF 4167
            +  DG   F
Sbjct: 134  ILPDGSLLF 142



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 12/112 (10%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPL-LTGSRVKTINDFG--- 3613
            P F   PSD+++ +N  A  +CR   +   S R+ W HNG  L L G + + I   G   
Sbjct: 84   PFFLEEPSDIVVKKNRQALLKCRAGGL--PSPRISWRHNGNDLNLAGDKRRKILPDGSLL 141

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVS-----CKLQVKGRQG-IILEP 3659
            F+ +E     + D G Y C A+++             KLQV G    I +EP
Sbjct: 142  FITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVKLQVAGLSSKITIEP 193



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 11/125 (8%)

Query: 3107 VLEILGTKTTDSGTYSCRATN---KWGQAEISVKLECV-DKSKGQKPRF-TTHIQNIEGL 3161
            V++I   +  D G Y C A N   K   +     L  + D+   ++  F  T    +  +
Sbjct: 246  VIQIRNVQLDDGGEYKCTAENPVTKRTHSSAYATLTVIPDRGNPRRADFVVTPPSRVVAI 305

Query: 3162 KDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGE 3221
            K G+    EC V     P   ++WY NGQ + + +R+  + +    ++ +  +   D+G 
Sbjct: 306  K-GKHTVLECAV--KGSPKPVVKWYKNGQIVTYDSRVTIIGESNLEIMQVVPS---DAGT 359

Query: 3222 YVCRA 3226
            Y C A
Sbjct: 360  YKCEA 364



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 3/79 (3%)

Query: 1721 RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDS 1780
            RV   +  H        G PK  V+W +NG  +   +R+T +   G   L +  V P D+
Sbjct: 301  RVVAIKGKHTVLECAVKGSPKPVVKWYKNGQIVTYDSRVTII---GESNLEIMQVVPSDA 357

Query: 1781 GTYTCRAINELGEAVTSST 1799
            GTY C A +   + V++ T
Sbjct: 358  GTYKCEATSSGSQPVSAET 376



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 4/99 (4%)

Query: 4402 EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            E  +K + PP+F K+++    +      F    DG P P + W +  + I  S DF   T
Sbjct: 375  ETRLKVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYWSKNGYKI-GSTDF---T 430

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
                  L +  +   D  ++   A N  G+ + SA L V
Sbjct: 431  KVGDGFLKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 6/95 (6%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            +G+    EC ++  P P   V+WY NG+++    R       G + L+I+ V   D+G Y
Sbjct: 306  KGKHTVLECAVKGSPKPV--VKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTY 360

Query: 1918 TCKAINNLGQAVSS-IRLNVQSKESIIRDSQHESA 1951
             C+A ++  Q VS+  RL V      I+  +  +A
Sbjct: 361  KCEATSSGSQPVSAETRLKVNYPPVFIKRLRDHNA 395



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 8/102 (7%)

Query: 3685 ITIEDEKPNPPR--FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS 3742
            +T+  ++ NP R  F V     +   +G     +C V+  G P   + W+ NG+     S
Sbjct: 280  LTVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDS 337

Query: 3743 RVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            RV  + +     L+I  +   DAG Y C AT+  GS   +A+
Sbjct: 338  RVTIIGESN---LEIMQVVPSDAGTYKCEATSS-GSQPVSAE 375



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 3/71 (4%)

Query: 786 RNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTV 845
           +  H   +      P   V+WYK+G+ +T  SR+T I   G  +L IM +   DAG+Y  
Sbjct: 306 KGKHTVLECAVKGSPKPVVKWYKNGQIVTYDSRVTII---GESNLEIMQVVPSDAGTYKC 362

Query: 846 RAVNKLGEAIS 856
            A +   + +S
Sbjct: 363 EATSSGSQPVS 373



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 39/150 (26%), Positives = 60/150 (40%), Gaps = 8/150 (5%)

Query: 2053 KATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFL 2112
            K T   G  +   +V++D   G Y  T +    K+      Y     I +    +R  F+
Sbjct: 238  KVTLLPGGVIQIRNVQLD-DGGEYKCTAENPVTKRTHS-SAYATLTVIPDRGNPRRADFV 295

Query: 2113 TALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDIL 2172
                S     +G     EC V+    P   + W+ NGQ +    R       G   L+I+
Sbjct: 296  VTPPSRVVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTI---IGESNLEIM 350

Query: 2173 YTYAEDSGTYMCKATNKLGEAVNTCT-LKV 2201
                 D+GTY C+AT+   + V+  T LKV
Sbjct: 351  QVVPSDAGTYKCEATSSGSQPVSAETRLKV 380



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 7/100 (7%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            V   P F+ R +   N   G  V F C  +     N  V W KNG  +     F  + D 
Sbjct: 380  VNYPPVFIKRLRD-HNAYTGSVVTFNCTADGNPKPN--VYWSKNGYKIG-STDFTKVGD- 434

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            G++ ++  DL+  D G+Y C A N +G+ + S  L+   T
Sbjct: 435  GFLKVE--DLLPSDMGMYQCFATNSLGSIQASAELSVYKT 472



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 6/96 (6%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            +   PVF   ++D          F       G+PK  V W +NG  I  S   T + D G
Sbjct: 380  VNYPPVFIKRLRDHNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI-GSTDFTKVGD-G 435

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            +  L ++ + P D G Y C A N LG    S+ L V
Sbjct: 436  F--LKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 6/99 (6%)

Query: 2903 VPDTEYPK-PEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK 2961
            +PD   P+  ++++   +    ++G+   LE  V  K  P   ++WY NG+++   SR  
Sbjct: 283  IPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAV--KGSPKPVVKWYKNGQIVTYDSRVT 340

Query: 2962 LTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            +    G   L+++ V   D+G Y C+A +   +  ++ T
Sbjct: 341  I---IGESNLEIMQVVPSDAGTYKCEATSSGSQPVSAET 376



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 5/74 (6%)

Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714
            ++G+H  LE  V+    P +K  W+KNG  +T  +R+      G   L I  +   D+G 
Sbjct: 305  IKGKHTVLECAVKGSPKPVVK--WYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGT 359

Query: 2715 YTCKATNLLGEAVS 2728
            Y C+AT+   + VS
Sbjct: 360  YKCEATSSGSQPVS 373



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 53/196 (27%), Positives = 78/196 (39%), Gaps = 29/196 (14%)

Query: 3429 IENLREGENAHFEARLT--PTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTY 3486
            I+ LR+  NA+  + +T   T D N K   YW+    K GS   T    GF  L++    
Sbjct: 387  IKRLRD-HNAYTGSVVTFNCTADGNPKPNVYWSKNGYKIGSTDFTKVGDGF--LKVEDLL 443

Query: 3487 PEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVD 3546
            P D G Y C A N+ G    +A + V      +  ++LP   +              T  
Sbjct: 444  PSDMGMYQCFATNSLGSIQASAELSVYKTGVPLPTTRLPTTAQ--------------TPT 489

Query: 3547 TLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
            T+ P   +  PP  TT P       +   + + R I  +DS + V W     P  T  +V
Sbjct: 490  TILPPTTTPTPPPTTTEPQ---RPPDPPRNVQARTI--SDSEIEVTWI---PPKNTYGKV 541

Query: 3607 KTINDFGFVILEIGGV 3622
             + N   F  L  GG+
Sbjct: 542  LSYN--MFFTLSKGGI 555



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 6/79 (7%)

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
            +GK+  LEC ++  G P   V+W+ NG+ VT  SR       G   L+I+    +D G Y
Sbjct: 306  KGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTY 360

Query: 1251 TVRAVNHLGSAHTSAIVRV 1269
               A +  GS   SA  R+
Sbjct: 361  KCEATSS-GSQPVSAETRL 378



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 5/78 (6%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPED 1379
            +  ++G +  LEC ++  G     V+W+ NG+ +    R     E +   L+++ V P D
Sbjct: 302  VVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTIIGESN---LEIMQVVPSD 356

Query: 1380 SGVYTCQATNQLGEAVTS 1397
            +G Y C+AT+   + V++
Sbjct: 357  AGTYKCEATSSGSQPVSA 374



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 12/106 (11%)

Query: 51  QVESSGDRQPITAG-RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKK 109
           +  SSG  QP++A  R     PP+F +  ++     G    F     GNP P V W++  
Sbjct: 363 EATSSGS-QPVSAETRLKVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYWSK-- 419

Query: 110 APLVECNKYSMRYNEQT--GDVSLLIKQIGPGDEGEYTCTARNQYG 153
                 N Y +   + T  GD  L ++ + P D G Y C A N  G
Sbjct: 420 ------NGYKIGSTDFTKVGDGFLKVEDLLPSDMGMYQCFATNSLG 459



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 7/102 (6%)

Query: 1835 DVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
            +  + VN  P FI +L      + G    + C  +  P PN  V W  NG  + S    +
Sbjct: 375  ETRLKVNYPPVFIKRLRDHNAYT-GSVVTFNCTADGNPKPN--VYWSKNGYKIGSTDFTK 431

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
              + F    L +  +   D G Y C A N+LG   +S  L+V
Sbjct: 432  VGDGF----LKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 15/127 (11%)

Query: 1940 ESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEA 1999
            E+ +    H SA   +  + D    +RA     FVV  P     IK       H V LE 
Sbjct: 265  ENPVTKRTHSSAYATLTVIPDRGNPRRA----DFVVTPPSRVVAIKGK-----HTV-LEC 314

Query: 2000 TLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
             +     P   V+WY NG+ V    R       G   L+I+     D GTY C+AT++  
Sbjct: 315  AVK--GSPKPVVKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTYKCEATSSGS 369

Query: 2060 EAVTTSS 2066
            + V+  +
Sbjct: 370  QPVSAET 376



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 3/54 (5%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            V+WY N + +   SR T     G   L+IM  +P D+GTY C A ++  + V++
Sbjct: 324  VKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTYKCEATSSGSQPVSA 374



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 7/97 (7%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            V   P+F   L+ ++    G  V      +    PN  + W KNG  + +    K    F
Sbjct: 380  VNYPPVFIKRLRDHNAYT-GSVVTFNCTADGNPKPN--VYWSKNGYKIGSTDFTKVGDGF 436

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                L +  L   D G+Y C ATN LG   ++A + +
Sbjct: 437  ----LKVEDLLPSDMGMYQCFATNSLGSIQASAELSV 469



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 7/75 (9%)

Query: 2513 VLTGPSELW--EGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDI 2570
            V+T PS +   +G+H   E  V   G P    +WY NG  +   SR       G   L+I
Sbjct: 295  VVTPPSRVVAIKGKHTVLECAVK--GSPKPVVKWYKNGQIVTYDSRVTI---IGESNLEI 349

Query: 2571 NSVVANDAGLYMCKA 2585
              VV +DAG Y C+A
Sbjct: 350  MQVVPSDAGTYKCEA 364



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 7/93 (7%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            PVF+  L    N   G    F C  +   +P   + W  NG KI  G    T    G++ 
Sbjct: 384  PVFIKRLRD-HNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI--GSTDFTKVGDGFLK 438

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            ++ L     D G Y C ATN LG    +  L V
Sbjct: 439  VEDLLP--SDMGMYQCFATNSLGSIQASAELSV 469



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 14/146 (9%)

Query: 1169 IEEISKSK--PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVG--S 1224
            + EI+ S+  P F++  S+   V + +   L+CR    G P+ R+ W HNG  + +    
Sbjct: 74   VNEITSSQLAPFFLEEPSDIV-VKKNRQALLKCRAG--GLPSPRISWRHNGNDLNLAGDK 130

Query: 1225 RFKTYYDFGFVALDIIHATSA--DTGEYTVRA---VNHLGSAHTSAIVRVIERSDIVTDT 1279
            R K   D   + + I H  S+  D G Y   A   VN+L     S IV+ ++ + + +  
Sbjct: 131  RRKILPDGSLLFITIEHTKSSKPDEGNYQCVASSQVNNLDYEIRSRIVK-LQVAGLSSKI 189

Query: 1280 QNEQAIEQIQLLEDAARRTKQVREDI 1305
              E    Q+ +  D AR   +VR  +
Sbjct: 190  TIEPVTSQV-IFGDVARLFCKVRHSL 214



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 17/46 (36%), Positives = 19/46 (41%)

Query: 4106 KARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            K   PPVF+          G    F C   G+PKP V W  NG  I
Sbjct: 379  KVNYPPVFIKRLRDHNAYTGSVVTFNCTADGNPKPNVYWSKNGYKI 424



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 2/91 (2%)

Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
            +   +S   T   + +    R     V+ P  V   +G+     C V G PKP V W  N
Sbjct: 270  KRTHSSAYATLTVIPDRGNPRRADFVVTPPSRVVAIKGKHTVLECAVKGSPKPVVKWYKN 329

Query: 4148 GNTIVNGSRYKLTYDGMYHFDIPKTRQYDTG 4178
            G  +   SR  +T  G  + +I +    D G
Sbjct: 330  GQIVTYDSR--VTIIGESNLEIMQVVPSDAG 358



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            + +V  +G +   EC V+ S  P +K  W+ N + +   +R     + +   L+I     
Sbjct: 300  SRVVAIKGKHTVLECAVKGSPKPVVK--WYKNGQIVTYDSRVTIIGESN---LEIMQVVP 354

Query: 2841 EDSGIYTCKATNSKGSATTSGSLR 2864
             D+G Y C+AT+S GS   S   R
Sbjct: 355  SDAGTYKCEATSS-GSQPVSAETR 377



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 5/72 (6%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           +G +   E  ++G+P PVV W  K   +V    Y  R     G+ +L I Q+ P D G Y
Sbjct: 306 KGKHTVLECAVKGSPKPVVKWY-KNGQIVT---YDSRVTI-IGESNLEIMQVVPSDAGTY 360

Query: 145 TCTARNQYGEAI 156
            C A +   + +
Sbjct: 361 KCEATSSGSQPV 372



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 6/98 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            + V   P F + L +     G+ V   C     G+    V W  NG  I +    +    
Sbjct: 378  LKVNYPPVFIKRLRDHNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKIGSTDFTKVGDG 435

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            F  V  DLL   P D G+Y C ATN LG    S  L V
Sbjct: 436  FLKVE-DLL---PSDMGMYQCFATNSLGSIQASAELSV 469



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 10/137 (7%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            PP F+  LR   + + G    F C  +    PN  + +  NG  + S     +   F   
Sbjct: 383  PPVFIKRLRDH-NAYTGSVVTFNCTADGNPKPN--VYWSKNGYKIGSTDFTKVGDGF--- 436

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAE 2360
             L ++  +P D G Y   A N+LG   ++  ++V   G  +  ++ P   +    +    
Sbjct: 437  -LKVEDLLPSDMGMYQCFATNSLGSIQASAELSVYKTGVPLPTTRLPTTAQTPTTI--LP 493

Query: 2361 PFKRPEIPEPVTR-QRP 2376
            P   P  P   T  QRP
Sbjct: 494  PTTTPTPPPTTTEPQRP 510



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 9/100 (9%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            PP F+ +++   +      T F C     G+P   V W  NG  +     FT + D G++
Sbjct: 383  PPVFIKRLRDHNAYTGSVVT-FNCTAD--GNPKPNVYWSKNGYKI-GSTDFTKVGD-GFL 437

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKT--TGKP 4069
             +    + P D G Y C ATN  G  +  A +    TG P
Sbjct: 438  KVED--LLPSDMGMYQCFATNSLGSIQASAELSVYKTGVP 475



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            PVF + L++  N   G    F+C     G+P   V W +N   I  S+  TK  D G++ 
Sbjct: 384  PVFIKRLRD-HNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI-GSTDFTKVGD-GFLK 438

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
              +  +   D G+Y C A+N LG
Sbjct: 439  --VEDLLPSDMGMYQCFATNSLG 459



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 56/201 (27%), Positives = 79/201 (39%), Gaps = 14/201 (6%)

Query: 3498 YNNYGEAVTTAS-MKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGN 3556
            Y N G+ VT  S + + G+ N+ +   +P    GT  K  A    S  V   T   +   
Sbjct: 327  YKN-GQIVTYDSRVTIIGESNLEIMQVVPSDA-GTY-KCEATSSGSQPVSAET-RLKVNY 382

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP F     D      S   F C      +    V W  NG  +  GS   T    GF  
Sbjct: 383  PPVFIKRLRDHNAYTGSVVTFNCTAD--GNPKPNVYWSKNGYKI--GSTDFTKVGDGF-- 436

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIIL-EPQLPSHFKSGTESIQKL 3675
            L++  +   D G+Y C ATN  G    S +L V  + G+ L   +LP+  ++ T +I   
Sbjct: 437  LKVEDLLPSDMGMYQCFATNSLGSIQASAELSVY-KTGVPLPTTRLPTTAQTPT-TILPP 494

Query: 3676 EETLHKREEITIEDEKPNPPR 3696
              T       T     P+PPR
Sbjct: 495  TTTPTPPPTTTEPQRPPDPPR 515



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 18/81 (22%), Positives = 39/81 (48%), Gaps = 4/81 (4%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ--RLINSNKHEIITTHNHTTL 323
           P   ++P +  +++   A  + +  G P PR++W  NG    L    + +I+   +   +
Sbjct: 84  PFFLEEPSDIVVKKNRQALLKCRAGGLPSPRISWRHNGNDLNLAGDKRRKILPDGSLLFI 143

Query: 324 RVRNTQ--KSDSGHYTLLAEN 342
            + +T+  K D G+Y  +A +
Sbjct: 144 TIEHTKSSKPDEGNYQCVASS 164



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%)

Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEY 2315
            +GK    EC V+    P   +++Y NG+ +   +R  I    G  +L+I   VP DAG Y
Sbjct: 306  KGKHTVLECAVKG--SPKPVVKWYKNGQIVTYDSRVTI---IGESNLEIMQVVPSDAGTY 360

Query: 2316 SVKAINALGHCTSA 2329
              +A ++     SA
Sbjct: 361  KCEATSSGSQPVSA 374



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 26/89 (29%), Positives = 34/89 (38%), Gaps = 6/89 (6%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            VFI  L +     G  + F C  + +  P   + W  N   + S    K    F    L 
Sbjct: 385  VFIKRLRDHNAYTGSVVTFNCTADGNPKPN--VYWSKNGYKIGSTDFTKVGDGF----LK 438

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
            +      D G+Y C ATNS GS   S  L
Sbjct: 439  VEDLLPSDMGMYQCFATNSLGSIQASAEL 467



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 3/52 (5%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
            G P   V+W++N +++   SR+T     G  ++ I  V   D G Y C A++
Sbjct: 318  GSPKPVVKWYKNGQIVTYDSRVT---IIGESNLEIMQVVPSDAGTYKCEATS 366



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 7/93 (7%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            PVF++ L +    + G  +   C  +  G+P   V W  NG  +  GS   T    GF+ 
Sbjct: 384  PVFIKRLRDHNAYT-GSVVTFNCTAD--GNPKPNVYWSKNGYKI--GSTDFTKVGDGFLK 438

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
            ++ +    +D G Y   A N LGS   SA + V
Sbjct: 439  VEDL--LPSDMGMYQCFATNSLGSIQASAELSV 469


>SB_37927| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1032

 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 86/318 (27%), Positives = 130/318 (40%), Gaps = 27/318 (8%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW-FKN--GQRLINSNKHEIITTHNHT 321
           PP ++ +P N+    G       Q  G+P P VTW FKN    + + S  + II   N  
Sbjct: 513 PPTVSGRPTNATRIVGESHTVTCQFQGSPAPLVTWFFKNDTADQTVPSTLNYII---NGG 569

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
            L ++   KSD G +     NP G    S  L V+       +    + +   Q R++ +
Sbjct: 570 ILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLRPLQTRDS-K 622

Query: 382 RIEISEKALAPQFVKVCQ-DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
            +++   A  P F+     +  V E     F+C+ +G P P VTW+     +     + I
Sbjct: 623 LVKLDVSASVPVFLDAGPVNVTVNETSTASFECQASGDPTPTVTWYRGQTALTHGGRYVI 682

Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
                G   L I     SD+G   C   N          L  ++    +      RF+ L
Sbjct: 683 -----GQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHL-FVQVPAAITSFTAPRFAQL 736

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
           N   G   ++     G P+PRITW +D   + P+   R+  +GG  +L I R   SD   
Sbjct: 737 N---GSTTLI-CLTRGIPSPRITWYRDRRVVTPDGS-RVTINGG--SLSIARVTRSDGGT 789

Query: 561 YQCTAQNVAGSTATRARL 578
           Y C A N AG T+  A L
Sbjct: 790 YACAASNAAGMTSRTANL 807



 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 104/416 (25%), Positives = 157/416 (37%), Gaps = 45/416 (10%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F+ K Q   V EH+         G P+P + W ++N  +    D    T  +   L I
Sbjct: 425  PTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQAV----DTNHVTLHSNGSLSI 480

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
             +V   D   ++ VA N  G+A   A L V+          VPP+ +    N     G+ 
Sbjct: 481  TRVLFSDRGSYSCVATNVAGSASSVATLTVQ----------VPPTVSGRPTNATRIVGES 530

Query: 4531 VRLDTKVTGTK-PIDVYWLKNGKKVQ--PDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
              +  +  G+  P+  ++ KN    Q  P   N I+       L I      D G + C 
Sbjct: 531  HTVTCQFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGG---ILTIKAVTKSDEGTFVCK 587

Query: 4588 AINSAGEARCDAECVVSLPAT--KDKPKPQTK---------AANAPPEIIEPLKDKIVAE 4636
              N AG A   A   V   +   +D    QT+         +A+ P  +     +  V E
Sbjct: 588  GTNPAGAAEASANLYVKGESMTPRDLRPLQTRDSKLVKLDVSASVPVFLDAGPVNVTVNE 647

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
                 F C+  G P PTV WY+G   +     + +     + TL I  + P D G+Y+C 
Sbjct: 648  TSTASFECQASGDPTPTVTWYRGQTALTHGGRYVIG----QGTLTILRSNPSDTGEYRCN 703

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI-KPTIQWL 4755
              N        A L V  P       A+T        +   +     +T  I  P I W 
Sbjct: 704  VTNGLATHVGVAHLFVQVP------AAITSFTAPRFAQLNGSTTLICLTRGIPSPRITWY 757

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            R+  ++  TPD   +   N   L I      D GT+ C A+ AAG    +A L ++
Sbjct: 758  RDRRVV--TPDGSRV-TINGGSLSIARVTRSDGGTYACAASNAAGMTSRTANLTIQ 810



 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 80/293 (27%), Positives = 114/293 (38%), Gaps = 27/293 (9%)

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVY--WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            NVT G  V L+     + PI V   W +N + VQ       +    + TL    A   D 
Sbjct: 340  NVTEGAPVSLECDPPNSYPIGVAITWFRNYQVVQ---LGSGITVSSSGTLTFATAKKADE 396

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G+Y C  +NS   A   +   ++L     +P   TK  N             V E Q++ 
Sbjct: 397  GEYFCSVVNSYLHASRSSS--IALLTVWVRPTFSTKPQNTT-----------VIEHQSLL 443

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
              C   G P+P+V W K ++ +  +     S  +    L I+     D G Y CVA N A
Sbjct: 444  LICAATGYPMPSVLWLKDNQAVDTNHVTLHSNGS----LSITRVLFSDRGSYSCVATNVA 499

Query: 4702 GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
            G  +  A L V  P      P  T    IV   G+      Q      P + W  +    
Sbjct: 500  GSASSVATLTVQVPPTVSGRP--TNATRIV---GESHTVTCQFQGSPAPLVTWFFKNDTA 554

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             +T    + +  N  +L I    + D GTF C+ T  AG  E SA L VK ++
Sbjct: 555  DQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKGES 607



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 76/307 (24%), Positives = 115/307 (37%), Gaps = 46/307 (14%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTL 4571
            V P+F+   QN  V   Q + L    TG     V WLK+ + V  D  +  L  +G  +L
Sbjct: 423  VRPTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQAV--DTNHVTLHSNG--SL 478

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
             I      D G Y CVA N AG A   A   V +P     P    +  NA          
Sbjct: 479  SITRVLFSDRGSYSCVATNVAGSASSVATLTVQVP-----PTVSGRPTNA---------T 524

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            +IV E   +  +C+  G P P V W+  +     +    ++   +   L I      DEG
Sbjct: 525  RIVGESHTV--TCQFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEG 582

Query: 4692 DYKCVAYNSAGRVTVAAKL--------------------KVTQPDQADNLPALTPLR--D 4729
             + C   N AG    +A L                    K+ + D + ++P        +
Sbjct: 583  TFVCKGTNPAGAAEASANLYVKGESMTPRDLRPLQTRDSKLVKLDVSASVPVFLDAGPVN 642

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            + V E   A F+ Q +    PT+ W R    +     + +I +G   +L    +   DTG
Sbjct: 643  VTVNETSTASFECQASGDPTPTVTWYRGQTALTHGGRY-VIGQGTLTIL---RSNPSDTG 698

Query: 4790 TFTCRAT 4796
             + C  T
Sbjct: 699  EYRCNVT 705



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 78/326 (23%), Positives = 115/326 (35%), Gaps = 45/326 (13%)

Query: 4433 EFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTA 4492
            +F G P PL+ W+ +N     +    ++      IL I+ V   D   F     N  G A
Sbjct: 536  QFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAA 595

Query: 4493 KCSANLVVEEKRRQGR-----------------GGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            + SANL V+ +    R                    VP        NV V        + 
Sbjct: 596  EASANLYVKGESMTPRDLRPLQTRDSKLVKLDVSASVPVFLDAGPVNVTVNETSTASFEC 655

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            + +G     V W +    +    R  I    G  TL IL + P D+G+Y C   N     
Sbjct: 656  QASGDPTPTVTWYRGQTALTHGGRYVI----GQGTLTILRSNPSDTGEYRCNVTNGLATH 711

Query: 4596 RCDAECVVSLPATKDK-PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV 4654
               A   V +PA       P+    N    +I                 C   G P P +
Sbjct: 712  VGVAHLFVQVPAAITSFTAPRFAQLNGSTTLI-----------------CLTRGIPSPRI 754

Query: 4655 QWYKGDKLIKPSKYFQMSR-TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV- 4712
             WY+  +++ P      SR T +  +L I+     D G Y C A N+AG  +  A L + 
Sbjct: 755  TWYRDRRVVTPDG----SRVTINGGSLSIARVTRSDGGTYACAASNAAGMTSRTANLTIQ 810

Query: 4713 TQPDQADNLPALTPLRDIVVYEGQPA 4738
              PD   ++ AL      +    +PA
Sbjct: 811  VPPDPPTDVSALPLTSTSIKLSWKPA 836



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 56/190 (29%), Positives = 75/190 (39%), Gaps = 14/190 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F    Q+  V E +     C  TG P P V W  +++ +  D NH  L     N +L 
Sbjct: 425 PTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQAV--DTNHVTL---HSNGSLS 479

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           IT V  SD G  +CVA N +G  +    L V      V P    R +      GE   + 
Sbjct: 480 ITRVLFSDRGSYSCVATNVAGSASSVATLTV-----QVPPTVSGRPTNATRIVGESHTVT 534

Query: 512 ARAVGTPTPRITW--QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +  G+P P +TW  + D         L    +GG   L I     SD   + C   N A
Sbjct: 535 CQFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGG--ILTIKAVTKSDEGTFVCKGTNPA 592

Query: 570 GSTATRARLY 579
           G+    A LY
Sbjct: 593 GAAEASANLY 602



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 16/195 (8%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P   V W+       Q       Y      L I      D GT++CK TN  G A  +++
Sbjct: 541  PAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEASAN 600

Query: 2067 VKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDR 2126
            + V  +S      +  + L+ +Q  +     K ++ +     PVFL A      + E   
Sbjct: 601  LYVKGES------MTPRDLRPLQTRDS----KLVKLDVSASVPVFLDAGPVNVTVNETST 650

Query: 2127 AHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKA 2186
            A FEC+     DP  T+ W+     +  G RY      G   L IL +   D+G Y C  
Sbjct: 651  ASFECQAS--GDPTPTVTWYRGQTALTHGGRY----VIGQGTLTILRSNPSDTGEYRCNV 704

Query: 2187 TNKLGEAVNTCTLKV 2201
            TN L   V    L V
Sbjct: 705  TNGLATHVGVAHLFV 719



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 53/188 (28%), Positives = 79/188 (42%), Gaps = 14/188 (7%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYP---EVTWFINDRQIRDDYNHKILVNESGNHAL 450
           F K    ++VTEG     +C      YP    +TWF N + ++      I V+ SG   L
Sbjct: 332 FHKHPSSQNVTEGAPVSLECDPPNS-YPIGVAITWFRNYQVVQ--LGSGITVSSSGT--L 386

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
                  +D G   C   N     +    + ++     V P F  +     V E + ++L
Sbjct: 387 TFATAKKADEGEYFCSVVNSYLHASRSSSIALLTVW--VRPTFSTKPQNTTVIEHQSLLL 444

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              A G P P + W KD   +  N  + +H++G   +L I R   SD   Y C A NVAG
Sbjct: 445 ICAATGYPMPSVLWLKDNQAVDTN-HVTLHSNG---SLSITRVLFSDRGSYSCVATNVAG 500

Query: 571 STATRARL 578
           S ++ A L
Sbjct: 501 SASSVATL 508



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 58/205 (28%), Positives = 79/205 (38%), Gaps = 18/205 (8%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   V W       + +   T  +      L +K V   D GT+ C+  N  G A  S
Sbjct: 539  GSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEAS 598

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857
            + L+V+       ES     L+ + Q  DS     + DV  +V   P F+        ++
Sbjct: 599  ANLYVKG------ESMTPRDLRPL-QTRDSKLV--KLDVSASV---PVFLDAGPVNVTVN 646

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
            E  +A +EC+     DP   V WY     L  G RY      G   L IL     D+GEY
Sbjct: 647  ETSTASFECQAS--GDPTPTVTWYRGQTALTHGGRY----VIGQGTLTILRSNPSDTGEY 700

Query: 1918 TCKAINNLGQAVSSIRLNVQSKESI 1942
             C   N L   V    L VQ   +I
Sbjct: 701  RCNVTNGLATHVGVAHLFVQVPAAI 725



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 62/245 (25%), Positives = 97/245 (39%), Gaps = 41/245 (16%)

Query: 238 ESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
           ES+T R +     + S  +   +    P  +   P N  + E + A F+ Q SG+P P V
Sbjct: 606 ESMTPRDLRPLQTRDSKLVKLDVSASVPVFLDAGPVNVTVNETSTASFECQASGDPTPTV 665

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
           TW++    L +  ++ I       TL +  +  SD+G Y         C VT+G      
Sbjct: 666 TWYRGQTALTHGGRYVI----GQGTLTILRSNPSDTGEYR--------CNVTNGLATHVG 713

Query: 358 PTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTG 417
               +VQ   +  IT                  AP+F ++        G  T   C   G
Sbjct: 714 VAHLFVQVPAA--ITSFT---------------APRFAQL-------NGSTTLI-CLTRG 748

Query: 418 RPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQ 477
            P P +TW+  DR++      ++ +N     +L I  VT SD G   C A N +G T+  
Sbjct: 749 IPSPRITWY-RDRRVVTPDGSRVTINGG---SLSIARVTRSDGGTYACAASNAAGMTSRT 804

Query: 478 CRLNV 482
             L +
Sbjct: 805 ANLTI 809



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 79/311 (25%), Positives = 117/311 (37%), Gaps = 33/311 (10%)

Query: 3065 IAHYEASLI--PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYS 3122
            I H    LI   TG     + W  + + ++ +H   T+++ G   L I     +D G+YS
Sbjct: 437  IEHQSLLLICAATGYPMPSVLWLKDNQAVDTNHV--TLHSNGS--LSITRVLFSDRGSYS 492

Query: 3123 CRATNKWGQAEISVKLEC-VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDM 3181
            C ATN  G A     L   V  +   +P   T+   I G     +  F+ +  P+     
Sbjct: 493  CVATNVAGSASSVATLTVQVPPTVSGRP---TNATRIVGESHTVTCQFQGSPAPL----- 544

Query: 3182 KIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINC 3241
             + W+        +            +L I      D G +VC+  N  G     A+ N 
Sbjct: 545  -VTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGA--AEASANL 601

Query: 3242 YGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAH 3301
            Y KG    ES+ P  L  ++  +S     +      SA  P F+        + E  +A 
Sbjct: 602  YVKG----ESMTPRDLRPLQTRDS-----KLVKLDVSASVPVFLDAGPVNVTVNETSTAS 652

Query: 3302 FEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATN 3361
            FE +     DP   V W+     L HG RY      G   L IL     ++GEY C  TN
Sbjct: 653  FECQ--ASGDPTPTVTWYRGQTALTHGGRY----VIGQGTLTILRSNPSDTGEYRCNVTN 706

Query: 3362 KLGRDSTKANL 3372
             L      A+L
Sbjct: 707  GLATHVGVAHL 717



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 53/164 (32%), Positives = 74/164 (45%), Gaps = 22/164 (13%)

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L I +V   D G +     N AG A+ SA++ V+  S   T    R L  +TR   +SK 
Sbjct: 571  LTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKGESM--TPRDLRPL--QTR---DSKL 623

Query: 1163 VEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTV 1222
            V+      ++S S PVF+        V+E      EC+    GDPT  V W+    ++T 
Sbjct: 624  VKL-----DVSASVPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTH 676

Query: 1223 GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN----HLGSAH 1262
            G R    Y  G   L I+ +  +DTGEY     N    H+G AH
Sbjct: 677  GGR----YVIGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAH 716



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 49/179 (27%), Positives = 80/179 (44%), Gaps = 22/179 (12%)

Query: 409 TRFDCRVTG--RPYPEVTWFINDRQIRDDYNHKILV---NESGNHA-LMITNVTLSDSGV 462
           T F C VTG  +P+  V W  +  ++ +     +L+   N S   A + + N+TL  +G 
Sbjct: 149 THFAC-VTGISKPFASVYWEKDGVKLTEYPTTSMLIPTDNPSWTSASISVRNITLKSAGF 207

Query: 463 VTCVARN-------KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
             CVA N       K  + A+   L  I+     AP F    S+  + E +   L    +
Sbjct: 208 YRCVAVNPMLPNLPKKSQPAYLQVLPAID-----APHFQVHPSSTTIAELQSAALQCHIL 262

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
           G PTP +TW+ +   ++ +P+ R     G  +L    A  + A  Y+CT  N  GS ++
Sbjct: 263 GVPTPSVTWEFNSNGLLDSPD-RYQLSNG--SLYFKSANRTMAGVYKCTGTNSVGSVSS 318



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 52/210 (24%), Positives = 80/210 (38%), Gaps = 22/210 (10%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            Q P  V+   +  + +  E+    CQ    G P   V WFF           T  Y    
Sbjct: 511  QVPPTVSGRPTNATRIVGESHTVTCQFQ--GSPAPLVTWFFKNDTADQTVPSTLNYIING 568

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREM 4090
              +    V   D G ++C+ TN  G  E  A +   G      +S  P+ ++ +      
Sbjct: 569  GILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLRPL------ 616

Query: 4091 EASWQVTPEQVVEESKARCPPVFVSL-PDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
                Q    ++V+   +   PVF+   P  VTV E   A F C+ +G P P V W     
Sbjct: 617  ----QTRDSKLVKLDVSASVPVFLDAGPVNVTVNETSTASFECQASGDPTPTVTWYRGQT 672

Query: 4150 TIVNGSRYKLTYDGMYHFDIPKTRQYDTGK 4179
             + +G RY +   G     I ++   DTG+
Sbjct: 673  ALTHGGRYVI---GQGTLTILRSNPSDTGE 699



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 57/217 (26%), Positives = 78/217 (35%), Gaps = 19/217 (8%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            G+S    C+ +  P P   V W+F             +       L I  V   D G + 
Sbjct: 528  GESHTVTCQFQGSPAP--LVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFV 585

Query: 1919 CKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKP 1978
            CK  N  G A +S  L V+ +    RD      L  +Q    DS+  +   D S  V   
Sbjct: 586  CKGTNPAGAAEASANLYVKGESMTPRD------LRPLQ--TRDSKLVKL--DVSASVPVF 635

Query: 1979 QFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
                P+ N  V E      E   +   DPT  V WY     +  G R    Y  G   L 
Sbjct: 636  LDAGPV-NVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTHGGR----YVIGQGTLT 688

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGL 2075
            IL +   DTG Y C  TN +   V  + + V   + +
Sbjct: 689  ILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQVPAAI 725



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 72/298 (24%), Positives = 109/298 (36%), Gaps = 40/298 (13%)

Query: 2938 KNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            +  P   + W+F     +Q     L        L +  V + D G + CK  N  G A  
Sbjct: 538  QGSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEA 597

Query: 2998 SSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDI 3057
            S+ +Y    +++  R   P        +Q  +  L K       D +   P F       
Sbjct: 598  SANLYVKG-ESMTPRDLRP--------LQTRDSKLVKL------DVSASVPVFLDAGPVN 642

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTD 3117
            V ++E   A +E     +GD +  + W Y G+T   +H  R  Y  G   L IL +  +D
Sbjct: 643  VTVNETSTASFECQA--SGDPTPTVTW-YRGQTA-LTHGGR--YVIGQGTLTILRSNPSD 696

Query: 3118 SGTYSCRATN----KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173
            +G Y C  TN      G A + V++     S    PRF      + G     S    C  
Sbjct: 697  TGEYRCNVTNGLATHVGVAHLFVQVPAAITS-FTAPRFA----QLNG-----STTLICLT 746

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              +  P  +I WY + + +       T++      L IA     D G Y C A N  G
Sbjct: 747  RGIPSP--RITWYRDRRVVTPDGSRVTINGGS---LSIARVTRSDGGTYACAASNAAG 799



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 46/165 (27%), Positives = 63/165 (38%), Gaps = 17/165 (10%)

Query: 2178 DSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEP 2237
            D GT++CK TN  G A  +  L V G      ++  P  L  +     Q   +++   + 
Sbjct: 580  DEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLRPL-----QTRDSKLVKLDV 628

Query: 2238 KISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDF 2297
              S P F+        V E  TA FECQ     DP   + +Y    AL    R+ I    
Sbjct: 629  SASVPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTHGGRYVI---- 682

Query: 2298 GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIIS 2342
            G  +L I    P D GEY     N L        + V    +I S
Sbjct: 683  GQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQVPAAITS 727



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 51/189 (26%), Positives = 76/189 (40%), Gaps = 23/189 (12%)

Query: 2676 IEWF-KNGVT-LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733
            + WF KN     T  + L    + G++T  I ++   D G + CK TN  G A ++A++ 
Sbjct: 545  VTWFFKNDTADQTVPSTLNYIINGGILT--IKAVTKSDEGTFVCKGTNPAGAAEASANLY 602

Query: 2734 IEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFI-SHLNNIVCKEGDNIH 2792
            ++      GES+ P  L  +                     VF+ +   N+   E     
Sbjct: 603  VK------GESMTPRDLRPL----QTRDSKLVKLDVSASVPVFLDAGPVNVTVNETSTAS 652

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852
            FEC  + S DPT  + W+     L  G RY         +L I  +   D+G Y C  TN
Sbjct: 653  FEC--QASGDPTPTVTWYRGQTALTHGGRYV----IGQGTLTILRSNPSDTGEYRCNVTN 706

Query: 2853 SKGSATTSG 2861
              G AT  G
Sbjct: 707  --GLATHVG 713



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 47/173 (27%), Positives = 66/173 (38%), Gaps = 19/173 (10%)

Query: 1637 LDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSK 1696
            L I +    D GT+ C+  N  G A  S         ++Y++   E   PR   L     
Sbjct: 571  LTIKAVTKSDEGTFVCKGTNPAGAAEASA--------NLYVKG--ESMTPR--DLRPLQT 618

Query: 1697 YQRHSAQDEVITQAPVF-TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
                  + +V    PVF      ++ V E   A FE +    GDP   V W R    +  
Sbjct: 619  RDSKLVKLDVSASVPVFLDAGPVNVTVNETSTASFECQ--ASGDPTPTVTWYRGQTALTH 676

Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
              R    +  G   L +   NP D+G Y C   N L   V  + LFVQ  A++
Sbjct: 677  GGR----YVIGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQVPAAI 725



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 55/188 (29%), Positives = 74/188 (39%), Gaps = 22/188 (11%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDF--GFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
            G P   + WF      A  +   TLN    G I L I  +   D G + C+ TN  G+A 
Sbjct: 539  GSPAPLVTWFFKNDT-ADQTVPSTLNYIINGGI-LTIKAVTKSDEGTFVCKGTNPAGAAE 596

Query: 3781 TTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHT 3840
             +A +          ES  P+      ++ L+  R S   K +   S P        + T
Sbjct: 597  ASANLYVKG------ESMTPR-----DLRPLQT-RDSKLVKLDVSASVPVFLDAGPVNVT 644

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E+    FEC  +   DP   + WYR    L  G RY  V   G  +L IL     D+G
Sbjct: 645  VNETSTASFEC--QASGDPTPTVTWYRGQTALTHGGRY--VIGQG--TLTILRSNPSDTG 698

Query: 3901 EYICRAVN 3908
            EY C   N
Sbjct: 699  EYRCNVTN 706



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 54/182 (29%), Positives = 75/182 (41%), Gaps = 22/182 (12%)

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            LTIK+VT  D G + C+  N  G A  SANL +        ES  P  L  +Q     +R
Sbjct: 571  LTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVK------GESMTPRDLRPLQ-----TR 619

Query: 1029 YSKRTEEEVKITQKPRFL--GPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
             SK  + +V     P FL  GP+  T  + E  +A FE   +   D T TV WY     +
Sbjct: 620  DSKLVKLDVS-ASVPVFLDAGPVNVT--VNETSTASFEC--QASGDPTPTVTWYRGQTAL 674

Query: 1087 TSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSI 1146
            T   R    +  G   L I      D+G Y     N        A + V+  ++I + + 
Sbjct: 675  THGGR----YVIGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQVPAAITSFTA 730

Query: 1147 HR 1148
             R
Sbjct: 731  PR 732



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 47/159 (29%), Positives = 58/159 (36%), Gaps = 22/159 (13%)

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKL 3675
            IL I  V + D G + CK TN  G A  S  L VKG      E   P   +     +Q  
Sbjct: 570  ILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLR----PLQTR 619

Query: 3676 EETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNG 3735
            +  L K       D   + P F      N+ V E     F+C+    GDPT  + W+   
Sbjct: 620  DSKLVKL------DVSASVPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQ 671

Query: 3736 RPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
                 G R       G   L I      D GEY C  TN
Sbjct: 672  TALTHGGRY----VIGQGTLTILRSNPSDTGEYRCNVTN 706



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 50/178 (28%), Positives = 77/178 (43%), Gaps = 23/178 (12%)

Query: 4537 VTG-TKPI-DVYWLKNGKKVQ--PDIRNKILEEDGTYT---LLILEAYPQDSGKYECVAI 4589
            VTG +KP   VYW K+G K+   P     I  ++ ++T   + +     + +G Y CVA+
Sbjct: 154  VTGISKPFASVYWEKDGVKLTEYPTTSMLIPTDNPSWTSASISVRNITLKSAGFYRCVAV 213

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQT-KAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N           + +LP        Q   A +AP   + P     +AE Q+    C I+G
Sbjct: 214  NPM---------LPNLPKKSQPAYLQVLPAIDAPHFQVHP-SSTTIAELQSAALQCHILG 263

Query: 4649 KPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
             P P+V W +  + L+     +Q+S      +L    A     G YKC   NS G V+
Sbjct: 264  VPTPSVTWEFNSNGLLDSPDRYQLSNG----SLYFKSANRTMAGVYKCTGTNSVGSVS 317



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 51/206 (24%), Positives = 77/206 (37%), Gaps = 23/206 (11%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSV--TVGSRFKTYYDFGFVALDIIHATSADTGE 1249
            G++  + C+ +  G P   V WF    +   TV S      + G + +  +  T +D G 
Sbjct: 528  GESHTVTCQFQ--GSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAV--TKSDEGT 583

Query: 1250 YTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQ 1309
            +  +  N  G+A  SA + V   S    D +  Q            R +K V+ D++   
Sbjct: 584  FVCKGTNPAGAAEASANLYVKGESMTPRDLRPLQT-----------RDSKLVKLDVSASV 632

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
                     N+   E +    EC  Q  GD T  V W+     +  G R    Y      
Sbjct: 633  PVFLDAGPVNVTVNETSTASFEC--QASGDPTPTVTWYRGQTALTHGGR----YVIGQGT 686

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAV 1395
            L +L   P D+G Y C  TN L   V
Sbjct: 687  LTILRSNPSDTGEYRCNVTNGLATHV 712



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 39/168 (23%), Positives = 64/168 (38%), Gaps = 18/168 (10%)

Query: 2568 LDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRPESWEQIQLKEAAMN 2627
            L I +V  +D G ++CK  N AG               +  + +RP      +L +  ++
Sbjct: 571  LTIKAVTKSDEGTFVCKGTNPAG-AAEASANLYVKGESMTPRDLRPLQTRDSKLVKLDVS 629

Query: 2628 KVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTT 2687
                +F+D G     +  T   S++    G             DP   + W++    LT 
Sbjct: 630  ASVPVFLDAGPVNVTVNETSTASFECQASG-------------DPTPTVTWYRGQTALTH 676

Query: 2688 GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            G R    +  G  TL+I      D+G Y C  TN L   V  A + ++
Sbjct: 677  GGR----YVIGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQ 720



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 56/223 (25%), Positives = 80/223 (35%), Gaps = 20/223 (8%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV   P  S    N   + G +  + C+ Q  G     V WF               Y 
Sbjct: 508  LTVQVPPTVSGRPTNATRIVGESHTVTCQFQ--GSPAPLVTWFFKNDTADQTVPSTLNYI 565

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYL 1424
             +   L + +V   D G + C+ TN  G A  S  L V        ES  P  L  +Q  
Sbjct: 566  INGGILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRDLRPLQ-- 617

Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG 1484
               +R  K   +D S ++ P F+        V E     FEC+     D    V W++  
Sbjct: 618  ---TRDSKLVKLDVSASV-PVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQ 671

Query: 1485 QPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527
              +T G R+      G   L I+     D+G Y C   N + T
Sbjct: 672  TALTHGGRY----VIGQGTLTILRSNPSDTGEYRCNVTNGLAT 710



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 46/207 (22%), Positives = 78/207 (37%), Gaps = 18/207 (8%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   + W     + + +   T  +      L + ++   D G + C+  +  G AE  
Sbjct: 539 GSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAGAAEAS 598

Query: 724 AVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGELQ 783
           A L+V      +  S  P  L+ +Q  +  SK    +     ++  P F+        + 
Sbjct: 599 ANLYV------KGESMTPRDLRPLQTRD--SKLVKLDV----SASVPVFLDAGPVNVTVN 646

Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
           E   A FE Q +   DPT  V WY+    +T   R    +  G  +L I+     D G Y
Sbjct: 647 ETSTASFECQAS--GDPTPTVTWYRGQTALTHGGR----YVIGQGTLTILRSNPSDTGEY 700

Query: 844 TVRAVNKLGEAISTASIRVAARSTVTA 870
                N L   +  A + V   + +T+
Sbjct: 701 RCNVTNGLATHVGVAHLFVQVPAAITS 727



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 54/226 (23%), Positives = 83/226 (36%), Gaps = 24/226 (10%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQP-VTIGHRFRPIH 1497
            +V + P    RP +   ++   H    C+ +  + + L   +FKN     T+      I 
Sbjct: 509  TVQVPPTVSGRPTNATRIVGESHT-VTCQFQG-SPAPLVTWFFKNDTADQTVPSTLNYII 566

Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQV 1557
            + G + +  +     D G + C+  N  G  E S  L  +  +   R       L  +Q 
Sbjct: 567  NGGILTIKAVT--KSDEGTFVCKGTNPAGAAEASANLYVKGESMTPRD------LRPLQT 618

Query: 1558 LEDRSKYHRTDMVDEVTTQAPI-CTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHN 1616
             +  SK  + D    V+   P+       NV + E   A FE +     D T  V WY  
Sbjct: 619  RD--SKLVKLD----VSASVPVFLDAGPVNVTVNETSTASFECQ--ASGDPTPTVTWYRG 670

Query: 1617 NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAV 1662
               L  G R+      G   L I+   P D+G Y C   N L   V
Sbjct: 671  QTALTHGGRYV----IGQGTLTILRSNPSDTGEYRCNVTNGLATHV 712



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 51/173 (29%), Positives = 65/173 (37%), Gaps = 22/173 (12%)

Query: 3341 ILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQTL 3400
            IL I    + + G + C  TN  G     ANL          +S  PR     L  LQT 
Sbjct: 570  ILTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKG------ESMTPRD----LRPLQT- 618

Query: 3401 EDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNG 3460
             DS + + D S        PVF         + E   A FE + +   DP   V WY   
Sbjct: 619  RDSKLVKLDVSAS-----VPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQ 671

Query: 3461 KSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
             +L  G R+      G   L I  + P D+GEY C   N     V  A + VQ
Sbjct: 672  TALTHGGRYV----IGQGTLTILRSNPSDTGEYRCNVTNGLATHVGVAHLFVQ 720



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 4/93 (4%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P  + KP+N+ + E          +G P P V W K+ Q  +++N    +T H++ +L +
Sbjct: 425 PTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQ-AVDTNH---VTLHSNGSLSI 480

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
                SD G Y+ +A N  G   +   L V+ P
Sbjct: 481 TRVLFSDRGSYSCVATNVAGSASSVATLTVQVP 513



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/66 (42%), Positives = 35/66 (53%), Gaps = 5/66 (7%)

Query: 942  RVEWLKDGRPVEAS-SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000
            R+ W +D R V    SR+T   N G  +L+I  VT  D G Y C A NA G  + +ANLT
Sbjct: 753  RITWYRDRRVVTPDGSRVT--INGG--SLSIARVTRSDGGTYACAASNAAGMTSRTANLT 808

Query: 1001 IVTKKD 1006
            I    D
Sbjct: 809  IQVPPD 814



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 46/182 (25%), Positives = 68/182 (37%), Gaps = 18/182 (9%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP F        + E +     C + G P P VTW  N   + D  +   L N S    L
Sbjct: 237 APHFQVHPSSTTIAELQSAALQCHILGVPTPSVTWEFNSNGLLDSPDRYQLSNGS----L 292

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
              +   + +GV  C   N  G  +       +     V   F +  S+ NV EG PV L
Sbjct: 293 YFKSANRTMAGVYKCTGTNSVGSVSSSPVFVGVAYFDFV---FHKHPSSQNVTEGAPVSL 349

Query: 511 -----NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
                N+  +G     ITW ++   +     + + + G   TL    AK +D   Y C+ 
Sbjct: 350 ECDPPNSYPIGV---AITWFRNYQVVQLGSGITVSSSG---TLTFATAKKADEGEYFCSV 403

Query: 566 QN 567
            N
Sbjct: 404 VN 405



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 18/154 (11%)

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L I+     D G +  K  N  G   ++ ++ V  KG    ES  P  L  ++  +S   
Sbjct: 571  LTIKAVTKSDEGTFVCKGTNPAGAAEASANLYV--KG----ESMTPRDLRPLQTRDSKL- 623

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
                 +   V+   PVF         + E  TA F+C+    GDPT  V W+R +  +  
Sbjct: 624  -----VKLDVSASVPVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTH 676

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASN 2455
              R    +  G  ++TI      D G Y C  +N
Sbjct: 677  GGR----YVIGQGTLTILRSNPSDTGEYRCNVTN 706



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 6/71 (8%)

Query: 80  NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPG 139
           N    +   A FE +  G+PTP V+W R +  L    +Y +      G  +L I +  P 
Sbjct: 642 NVTVNETSTASFECQASGDPTPTVTWYRGQTALTHGGRYVI------GQGTLTILRSNPS 695

Query: 140 DEGEYTCTARN 150
           D GEY C   N
Sbjct: 696 DTGEYRCNVTN 706



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 26/80 (32%), Positives = 33/80 (41%), Gaps = 6/80 (7%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P F+       ++ E  T  FECQ +  GDP   V W+     L H  R    Y  G   
Sbjct: 633  PVFLDAGPVNVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTHGGR----YVIGQGT 686

Query: 4033 MNFGWVYPEDSGEYLCRATN 4052
            +      P D+GEY C  TN
Sbjct: 687  LTILRSNPSDTGEYRCNVTN 706



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 40/184 (21%), Positives = 64/184 (34%), Gaps = 16/184 (8%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGEXXXX 2463
            G P   V WF      + +   T  +      +TI  V   DEG ++C+ +N  G     
Sbjct: 539  GSPAPLVTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFVCKGTNPAG----- 593

Query: 2464 XXXXXXXXXXIQLETQHPEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEG 2523
                      ++ E+  P  ++ +    Q  + +  + D     P+F     GP  +   
Sbjct: 594  -AAEASANLYVKGESMTPRDLRPL----QTRDSKLVKLDVSASVPVFLD--AGPVNVTVN 646

Query: 2524 QHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMC 2583
            + +         GDP+    WY     L  G R+      G  TL I     +D G Y C
Sbjct: 647  ETSTASFECQASGDPTPTVTWYRGQTALTHGGRY----VIGQGTLTILRSNPSDTGEYRC 702

Query: 2584 KAIN 2587
               N
Sbjct: 703  NVTN 706



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 9/148 (6%)

Query: 1790 ELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQ 1849
            +LG  +T S+    + A+ +   + E     +     +SR      + V V   P F T+
Sbjct: 373  QLGSGITVSSSGTLTFATAKKADEGEYFCSVVNSYLHASRSSSIALLTVWVR--PTFSTK 430

Query: 1850 LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTV 1909
                T + E QS    C    YP P+  V W  + + + + H    SN     +L I  V
Sbjct: 431  PQNTTVI-EHQSLLLICAATGYPMPS--VLWLKDNQAVDTNHVTLHSN----GSLSITRV 483

Query: 1910 YGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
               D G Y+C A N  G A S   L VQ
Sbjct: 484  LFSDRGSYSCVATNVAGSASSVATLTVQ 511



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 5/64 (7%)

Query: 800 PTMRVEWYKDGRPITA-SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
           P+ R+ WY+D R +T   SR+T   N G  SL+I  +   D G+Y   A N  G    TA
Sbjct: 750 PSPRITWYRDRRVVTPDGSRVT--INGG--SLSIARVTRSDGGTYACAASNAAGMTSRTA 805

Query: 859 SIRV 862
           ++ +
Sbjct: 806 NLTI 809



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 6/89 (6%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F    +  T ++E QSA  +C I   P P++  E+  NG +L S  RY+ SN     
Sbjct: 237  APHFQVHPSSTT-IAELQSAALQCHILGVPTPSVTWEFNSNG-LLDSPDRYQLSN----G 290

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSS 1931
            +L   +     +G Y C   N++G   SS
Sbjct: 291  SLYFKSANRTMAGVYKCTGTNSVGSVSSS 319



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 3/70 (4%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
           G P PR+TW+++ +R++  +   +  T N  +L +    +SD G Y   A N  G    +
Sbjct: 748 GIPSPRITWYRD-RRVVTPDGSRV--TINGGSLSIARVTRSDGGTYACAASNAAGMTSRT 804

Query: 351 GYLAVESPTE 360
             L ++ P +
Sbjct: 805 ANLTIQVPPD 814



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V ++P F T+P++   VIE Q +   C        +  V W K+ Q V   H    +H 
Sbjct: 420  TVWVRPTFSTKPQNT-TVIEHQSLLLICAATGYPMPS--VLWLKDNQAVDTNHV--TLHS 474

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
             G  +L I  ++  D G Y+C A N+ G+      LT
Sbjct: 475  NG--SLSITRVLFSDRGSYSCVATNVAGSASSVATLT 509



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG-SRYKLTYDGMY 4165
            P F   P + T+ E + A   C + G P P V W  N N +++   RY+L+   +Y
Sbjct: 238  PHFQVHPSSTTIAELQSAALQCHILGVPTPSVTWEFNSNGLLDSPDRYQLSNGSLY 293



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 4/59 (6%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            V WLKD + V+ ++ +T   N    +L+I  V   D G Y+C A N  G A++ A LT+
Sbjct: 456  VLWLKDNQAVD-TNHVTLHSNG---SLSITRVLFSDRGSYSCVATNVAGSASSVATLTV 510



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 3723 GDPTMRIDWFHNGRPFAT-GSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
            G P+ RI W+ + R     GSRV T+N     +L I  +   D G Y C A+N  G  + 
Sbjct: 748  GIPSPRITWYRDRRVVTPDGSRV-TINGG---SLSIARVTRSDGGTYACAASNAAGMTSR 803

Query: 3782 TAKITCSAKRD 3792
            TA +T     D
Sbjct: 804  TANLTIQVPPD 814



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 46/203 (22%), Positives = 71/203 (34%), Gaps = 24/203 (11%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G++    C  + S  P   + WFF N            +  +   L I    + D G + 
Sbjct: 528  GESHTVTCQFQGSPAPL--VTWFFKNDTADQTVPSTLNYIINGGILTIKAVTKSDEGTFV 585

Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTE 2907
            CK TN  G+A  S +L   G      ++  P+    L    Q  +++L K       D  
Sbjct: 586  CKGTNPAGAAEASANLYVKG------ESMTPRDLRPL----QTRDSKLVK------LDVS 629

Query: 2908 YPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFG 2967
               P ++        + E      E Q     DP   + WY     L  G R+ +    G
Sbjct: 630  ASVPVFLDAGPVNVTVNETSTASFECQA--SGDPTPTVTWYRGQTALTHGGRYVI----G 683

Query: 2968 FVTLDLVDVYERDSGIYTCKAYN 2990
              TL ++     D+G Y C   N
Sbjct: 684  QGTLTILRSNPSDTGEYRCNVTN 706



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 5/56 (8%)

Query: 2404 GDPTLKVEWFRNEKLIE-DSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            G P+ ++ W+R+ +++  D SR+T        S++I+ V   D G Y C ASN  G
Sbjct: 748  GIPSPRITWYRDRRVVTPDGSRVTINGG----SLSIARVTRSDGGTYACAASNAAG 799



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 6/93 (6%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F +      +AE Q+A  +  ++ V  P +  E+  NG+ +++ +R    +     +
Sbjct: 237  APHFQVHPSSTTIAELQSAALQCHILGVPTPSVTWEFNSNGL-LDSPDR----YQLSNGS 291

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
            L  K  N   +G Y C   N +G +V+SS +FV
Sbjct: 292  LYFKSANRTMAGVYKCTGTNSVG-SVSSSPVFV 323



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 6/93 (6%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F+   ++  V E+Q+          G P   V WL++   ++ ++   T+H  G  +L
Sbjct: 425  PTFSTKPQNTTVIEHQSLLLICAA--TGYPMPSVLWLKDNQAVDTNH--VTLHSNG--SL 478

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            ++  V   D G+Y+C A N  G A + +TL VQ
Sbjct: 479  SITRVLFSDRGSYSCVATNVAGSASSVATLTVQ 511



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 5/96 (5%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            Q P  IT    P       S    C     P P  R+ WY + +V+       T N    
Sbjct: 720  QVPAAITSFTAPRFAQLNGSTTLICLTRGIPSP--RITWYRDRRVVTPDGSRVTING--- 774

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
             +L I  V   D G Y C A N  G    +  L +Q
Sbjct: 775  GSLSIARVTRSDGGTYACAASNAAGMTSRTANLTIQ 810



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP       NA    G +     + +G+P P+V+W  K     +    ++ Y    G   
Sbjct: 513 PPTVSGRPTNATRIVGESHTVTCQFQGSPAPLVTWFFKNDTADQTVPSTLNYIINGG--I 570

Query: 131 LLIKQIGPGDEGEYTCTARNQYG--EAICSVYIQPE 164
           L IK +   DEG + C   N  G  EA  ++Y++ E
Sbjct: 571 LTIKAVTKSDEGTFVCKGTNPAGAAEASANLYVKGE 606



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704
           +VT  E     FE +    GDPT  + W +   ++    R+      G  +L +L  N  
Sbjct: 642 NVTVNETSTASFECQAS--GDPTPTVTWYRGQTALTHGGRYV----IGQGTLTILRSNPS 695

Query: 705 DSGEYTCRAVSATGVAETKAVLHV 728
           D+GEY C   +  G+A    V H+
Sbjct: 696 DTGEYRCNVTN--GLATHVGVAHL 717



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 43/171 (25%), Positives = 63/171 (36%), Gaps = 12/171 (7%)

Query: 3060 ISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSG 3119
            I+E Q A  +  ++     S+  E+  NG  +++  R    Y      L       T +G
Sbjct: 249  IAELQSAALQCHILGVPTPSVTWEFNSNG-LLDSPDR----YQLSNGSLYFKSANRTMAG 303

Query: 3120 TYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDP 3179
             Y C  TN  G    S     V         F  H  + + + +G     EC        
Sbjct: 304  VYKCTGTNSVGSVSSSPVFVGVAYFDFV---FHKHPSS-QNVTEGAPVSLECDPPNSYPI 359

Query: 3180 DMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
             + I W+ N Q ++  + I TVS  G   L  A  +  D GEY C   N Y
Sbjct: 360  GVAITWFRNYQVVQLGSGI-TVSSSG--TLTFATAKKADEGEYFCSVVNSY 407



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 14/41 (34%), Positives = 20/41 (48%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P F + P   TV E +     C  TG+P P V+WL +   +
Sbjct: 425  PTFSTKPQNTTVIEHQSLLLICAATGYPMPSVLWLKDNQAV 465



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 5/65 (7%)

Query: 2672 PNLKIEWFKNGVTLTT-GARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P+ +I W+++   +T  G+R+  T + G  +LSI  +   D G Y C A+N  G    TA
Sbjct: 750  PSPRITWYRDRRVVTPDGSRV--TINGG--SLSIARVTRSDGGTYACAASNAAGMTSRTA 805

Query: 2731 SIKIE 2735
            ++ I+
Sbjct: 806  NLTIQ 810



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 5/89 (5%)

Query: 1980 FGKPIKNAEVTEGHPVHLEATLTPVNDPT-MRVEWYCNGRPVQQGHRFKTTYDFGYVALD 2038
            F K   +  VTEG PV LE    P + P  + + W+ N + VQ G    T    G   L 
Sbjct: 332  FHKHPSSQNVTEGAPVSLECD-PPNSYPIGVAITWFRNYQVVQLGSGI-TVSSSG--TLT 387

Query: 2039 ILYAYAEDTGTYMCKATNAVGEAVTTSSV 2067
               A   D G Y C   N+   A  +SS+
Sbjct: 388  FATAKKADEGEYFCSVVNSYLHASRSSSI 416



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 7/84 (8%)

Query: 2375 RPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYV 2434
            RP F+   QN   I E Q+    C     G P   V W ++ + + D++ +T  H  G  
Sbjct: 424  RPTFSTKPQNTTVI-EHQSLLLICAA--TGYPMPSVLWLKDNQAV-DTNHVT-LHSNG-- 476

Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458
            S++I+ V   D G Y C A+N+ G
Sbjct: 477  SLSITRVLFSDRGSYSCVATNVAG 500



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 5/69 (7%)

Query: 3859 PKLRIEWYRNGKLL-PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKA 3917
            P  RI WYR+ +++ P G R     + G  SL I  V   D G Y C A N  G     A
Sbjct: 750  PSPRITWYRDRRVVTPDGSR--VTINGG--SLSIARVTRSDGGTYACAASNAAGMTSRTA 805

Query: 3918 TISCKKLPD 3926
             ++ +  PD
Sbjct: 806  NLTIQVPPD 814



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 9/72 (12%)

Query: 2387 NIQEGQTAHFDC---RLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRD 2443
            N+ EG     +C      P+G   + + WFRN ++++  S IT +      ++T +  + 
Sbjct: 340  NVTEGAPVSLECDPPNSYPIG---VAITWFRNYQVVQLGSGITVSSS---GTLTFATAKK 393

Query: 2444 EDEGVYMCRASN 2455
             DEG Y C   N
Sbjct: 394  ADEGEYFCSVVN 405



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F T+ ++ TV E + +   C       P   + W ++ + + + H   T++  G  SL
Sbjct: 425  PTFSTKPQNTTVIEHQSLLLICAATGYPMPS--VLWLKDNQAVDTNHV--TLHSNG--SL 478

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDI 3927
             I  V   D G Y C A N  G   + AT++ +  P +
Sbjct: 479  SITRVLFSDRGSYSCVATNVAGSASSVATLTVQVPPTV 516



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 4/63 (6%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCT 2198
            P  ++ W  + Q +   H   T H  G  +L I      D G+Y C ATN  G A +  T
Sbjct: 452  PMPSVLWLKDNQAVDTNHV--TLHSNG--SLSITRVLFSDRGSYSCVATNVAGSASSVAT 507

Query: 2199 LKV 2201
            L V
Sbjct: 508  LTV 510



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P   + W  +N+ +   T + + H  S  SL IT     D G Y+C ATN  GSA++  +
Sbjct: 452  PMPSVLWLKDNQAVD--TNHVTLH--SNGSLSITRVLFSDRGSYSCVATNVAGSASSVAT 507

Query: 2863 L 2863
            L
Sbjct: 508  L 508



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            P+ R+ WY + R V      + T + G  +L I      D GTY C A+NA G    T++
Sbjct: 750  PSPRITWYRDRRVVTPDGS-RVTINGG--SLSIARVTRSDGGTYACAASNAAGMTSRTAN 806

Query: 2067 VKV 2069
            + +
Sbjct: 807  LTI 809



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 3/80 (3%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            +V EG PV  +C         + I WF N +    GS + T++  G   L        D 
Sbjct: 340  NVTEGAPVSLECDPPNSYPIGVAITWFRNYQVVQLGSGI-TVSSSG--TLTFATAKKADE 396

Query: 3766 GEYTCRATNKWGSATTTAKI 3785
            GEY C   N +  A+ ++ I
Sbjct: 397  GEYFCSVVNSYLHASRSSSI 416



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   + WLK+ Q+++ +    ++   G  SL +  +   D G Y+C A +  G A + 
Sbjct: 450 GYPMPSVLWLKDNQAVDTNH--VTLHSNG--SLSITRVLFSDRGSYSCVATNVAGSASSV 505

Query: 724 AVLHVTPRATI 734
           A L V    T+
Sbjct: 506 ATLTVQVPPTV 516



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 1080 YFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRS 1139
            +    Q    N + T H  G  +L I  V   D G Y+ VA N AG A   A++TV+   
Sbjct: 458  WLKDNQAVDTNHV-TLHSNG--SLSITRVLFSDRGSYSCVATNVAGSASSVATLTVQVPP 514

Query: 1140 SI 1141
            ++
Sbjct: 515  TV 516



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/92 (22%), Positives = 43/92 (46%), Gaps = 5/92 (5%)

Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS-NKHEIITTH 318
           L  +  P     P ++ + E   A  Q  + G P P VTW  N   L++S +++++    
Sbjct: 232 LPAIDAPHFQVHPSSTTIAELQSAALQCHILGVPTPSVTWEFNSNGLLDSPDRYQL---- 287

Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
           ++ +L  ++  ++ +G Y     N  G + +S
Sbjct: 288 SNGSLYFKSANRTMAGVYKCTGTNSVGSVSSS 319



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 5/59 (8%)

Query: 2803 PTLKIEWFFN-NKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
            PT  + W FN N  L S  RY+ ++     SL         +G+Y C  TNS GS ++S
Sbjct: 265  PTPSVTWEFNSNGLLDSPDRYQLSNG----SLYFKSANRTMAGVYKCTGTNSVGSVSSS 319



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 3/97 (3%)

Query: 3814 GRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLP 3873
            G +S +P    +      F     S  V E   V  EC         + I W+RN +++ 
Sbjct: 314  GSVSSSPVFVGVAYFDFVFHKHPSSQNVTEGAPVSLECDPPNSYPIGVAITWFRNYQVVQ 373

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDF 3910
             G    TV   G  +L        D GEY C  VN +
Sbjct: 374  LGSGI-TVSSSG--TLTFATAKKADEGEYFCSVVNSY 407



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 6/98 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV   P FS    N   +E  ++ L C     G     V W  + + + T H       
Sbjct: 419  LTVWVRPTFSTKPQNTTVIEHQSLLLICAA--TGYPMPSVLWLKDNQAVDTNH----VTL 472

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                +L +  V   D G Y+C ATN  G A +   L V
Sbjct: 473  HSNGSLSITRVLFSDRGSYSCVATNVAGSASSVATLTV 510



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 4/70 (5%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P   V W KD + +  +    ++ + G  SL+I  +   D GSY+  A N  G A S A+
Sbjct: 452 PMPSVLWLKDNQAVDTNH--VTLHSNG--SLSITRVLFSDRGSYSCVATNVAGSASSVAT 507

Query: 860 IRVAARSTVT 869
           + V    TV+
Sbjct: 508 LTVQVPPTVS 517



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 14/35 (40%), Positives = 22/35 (62%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            +LSI  +   D G Y+C ATN+ G A S A++ ++
Sbjct: 477  SLSITRVLFSDRGSYSCVATNVAGSASSVATLTVQ 511



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 3/60 (5%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + WY + + +T      T +     +L IA V   D G Y   A NAAG    +A++T++
Sbjct: 754  ITWYRDRRVVTPDGSRVTINGG---SLSIARVTRSDGGTYACAASNAAGMTSRTANLTIQ 810


>SB_19226| Best HMM Match : I-set (HMM E-Value=0)
          Length = 1500

 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 106/429 (24%), Positives = 158/429 (36%), Gaps = 52/429 (12%)

Query: 4383 TSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI 4442
            T+  T   E  A    ++V  P      P  T  +    +   E A  +    G P P  
Sbjct: 446  TAVNTLTGETHASNPAKLVVVPSSSPFAPRMTSLVHNLTLIAGETAVLQCTAAGSPTPYF 505

Query: 4443 KWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
            +W +    +       +    +   L+I      D A +   A N  G+   +  L V  
Sbjct: 506  RWLKSGKSLTMGGRMSVIAGGS---LMIESTMASDEANYTCQAVNNVGSVHMAIYLEV-- 560

Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSG-QLVRLDTKVTGTKPIDVYWLKNGKKV-QPDIRN 4560
                    IVP +F    +      G     ++  VTG     + W +N + + QP  R 
Sbjct: 561  --------IVPITFKERPKPQAAQVGFPRKNMECDVTGEPEPKITWYQNAQSLGQPKGRI 612

Query: 4561 KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAAN 4620
             I + D    L+I   Y QD+G Y+CVA N     +  AE           P        
Sbjct: 613  SIRDND----LVIATVYGQDNGVYQCVADNGRELVQSSAEFYAGFSVPTFNP-------- 660

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGD-KLIKPSKYFQMSRTADEY 4678
              P+I       I+  G  ++ +C++   P P  VQWY  D  L     Y   +    + 
Sbjct: 661  GTPDI-------ILYPGTPLQITCEVSAIPYPRDVQWYHDDIPLTGGHDYIITAMPGTKR 713

Query: 4679 TLRISE-----AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVV- 4732
            + R+S+         D G+YKCVA N+AG      K+ V  P      P +T  R  V  
Sbjct: 714  SSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVYVRGP------PNITSFRSSVTG 767

Query: 4733 YEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
             +G       +      P I W R G  IP    +      +N  LLIGN  + D+G +T
Sbjct: 768  VQGDTISLPCRAKGFPPPVITWSRSGQTIP----YDRRQSIDNGTLLIGNVQKSDSGKYT 823

Query: 4793 CRATTAAGQ 4801
            C A   AG+
Sbjct: 824  CTAVNTAGE 832



 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 98/389 (25%), Positives = 148/389 (38%), Gaps = 46/389 (11%)

Query: 4431 EVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG 4490
            E +  GEP P I WY +N      P  +I        L+I  V+ +D+ V+  VA+N   
Sbjct: 585  ECDVTGEPEPKITWY-QNAQSLGQPKGRISIRDND--LVIATVYGQDNGVYQCVADNGRE 641

Query: 4491 TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLK 4549
              + SA             G   P+F     ++ +  G  +++  +V+    P DV W  
Sbjct: 642  LVQSSAEFYA---------GFSVPTFNPGTPDIILYPGTPLQITCEVSAIPYPRDVQWYH 692

Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQ------DSGKYECVAINSAGEARCDAECVV 4603
            +   +       I    GT     L    +      DSG+Y+CVA N+AG A    E V+
Sbjct: 693  DDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSA----EQVI 748

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
             +                PP I          +G  I   C+  G P P + W +  + I
Sbjct: 749  KV------------YVRGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTI 796

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPA 4723
                 +   ++ D  TL I      D G Y C A N+AG      +  VT        P 
Sbjct: 797  P----YDRRQSIDNGTLLIGNVQKSDSGKYTCTAVNTAGE-----RDSVTMTVSIVVSPR 847

Query: 4724 LTPLRDIVVYEGQPAQFKTQITSKIKP-TIQWLREGALIPETP-DFQMIHEGNNAVLLIG 4781
            +TP     V EGQ   +   +     P  I WLR+G  +   P D +++     + L I 
Sbjct: 848  ITPFMWAPVDEGQREHYTCVVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIP 907

Query: 4782 NTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
               +   G +TC     AG    SA+L+V
Sbjct: 908  QVMQRHQGVYTCIVGNRAGIARHSAQLIV 936



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 74/306 (24%), Positives = 125/306 (40%), Gaps = 34/306 (11%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P  T    N+ + +G+   L     G+      WLK+GK +    R  ++      +L+I
Sbjct: 474  PRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIAGG---SLMI 530

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT-KDKPKPQTKAANAPPEIIEPLKDK 4632
                  D   Y C A+N+ G         V +P T K++PKPQ      P + +E     
Sbjct: 531  ESTMASDEANYTCQAVNNVGSVHMAIYLEVIVPITFKERPKPQAAQVGFPRKNME----- 585

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
                       C + G+P P + WY+  + +   K     R  D   L I+  + +D G 
Sbjct: 586  -----------CDVTGEPEPKITWYQNAQSLGQPKGRISIRDND---LVIATVYGQDNGV 631

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT- 4751
            Y+CVA N  GR  V +  +             TP  DI++Y G P Q   ++++   P  
Sbjct: 632  YQCVADN--GRELVQSSAEFYAGFSVPTFNPGTP--DIILYPGTPLQITCEVSAIPYPRD 687

Query: 4752 IQWLREGALIPETPDFQMIH----EGNNAVLLIGNTYEE--DTGTFTCRATTAAGQVETS 4805
            +QW  +   +    D+ +      + ++ +  +  T     D+G + C A+ AAG  E  
Sbjct: 688  VQWYHDDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQV 747

Query: 4806 AKLVVK 4811
             K+ V+
Sbjct: 748  IKVYVR 753



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 63/209 (30%), Positives = 90/209 (43%), Gaps = 17/209 (8%)

Query: 369 QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFI 427
           Q + D  +   +   E       P F     D  +  G   +  C V+  PYP +V W+ 
Sbjct: 633 QCVADNGRELVQSSAEFYAGFSVPTFNPGTPDIILYPGTPLQITCEVSAIPYPRDVQWYH 692

Query: 428 NDRQIRDDYNHKILV-----NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           +D  +   +++ I         S    L  T V+++DSG   CVA N +G         V
Sbjct: 693 DDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSAE-----QV 747

Query: 483 IEKEQVVAPKFVERF-STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT 541
           I K  V  P  +  F S++   +G+ + L  RA G P P ITW + G   IP  + R   
Sbjct: 748 I-KVYVRGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSG-QTIPY-DRRQSI 804

Query: 542 DGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           D G  TL I   + SD+  Y CTA N AG
Sbjct: 805 DNG--TLLIGNVQKSDSGKYTCTAVNTAG 831



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 56/176 (31%), Positives = 72/176 (40%), Gaps = 12/176 (6%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           +G      CR  G P P +TW  + + I  D    I      N  L+I NV  SDSG  T
Sbjct: 769 QGDTISLPCRAKGFPPPVITWSRSGQTIPYDRRQSI-----DNGTLLIGNVQKSDSGKYT 823

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN-ARAVGTPTPRIT 523
           C A N +GE     R +V     +V    +  F    V EG+        A G     IT
Sbjct: 824 CTAVNTAGE-----RDSVTMTVSIVVSPRITPFMWAPVDEGQREHYTCVVAEGDMPCNIT 878

Query: 524 WQKDGVPIIPNP-ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           W +DG P+   P +L I T    S+L IP+        Y C   N AG     A+L
Sbjct: 879 WLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQL 934



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 46/175 (26%), Positives = 71/175 (40%), Gaps = 15/175 (8%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           +C VTG P P++TW+ N + +      +I + ++    L+I  V   D+GV  CVA N  
Sbjct: 585 ECDVTGEPEPKITWYQNAQSLGQP-KGRISIRDND---LVIATVYGQDNGVYQCVADN-- 638

Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR-ITWQKDGVP 530
           G    Q          V  P F      + +  G P+ +       P PR + W  D +P
Sbjct: 639 GRELVQSSAEFYAGFSV--PTFNPGTPDIILYPGTPLQITCEVSAIPYPRDVQWYHDDIP 696

Query: 531 IIPNPELRIHTDGGA------STLDIPRAKASDAAWYQCTAQNVAGSTATRARLY 579
           +    +  I    G       S L       +D+  Y+C A N AGS     ++Y
Sbjct: 697 LTGGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVY 751



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 7/126 (5%)

Query: 450 LMITNVTLSDSGVVT--CVARNKSGET--AFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
           L+ITN    D   +         +GET  +   +L V+      AP+       L +  G
Sbjct: 429 LVITNAHAEDENSMYHWTAVNTLTGETHASNPAKLVVVPSSSPFAPRMTSLVHNLTLIAG 488

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           E  VL   A G+PTP   W K G  +     + +   G   +L I    ASD A Y C A
Sbjct: 489 ETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIAGG---SLMIESTMASDEANYTCQA 545

Query: 566 QNVAGS 571
            N  GS
Sbjct: 546 VNNVGS 551



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 58/248 (23%), Positives = 88/248 (35%), Gaps = 18/248 (7%)

Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI-SEKALAP 392
           G YT++   P+G +V +   A E     Y     +    +T      + + + S    AP
Sbjct: 419 GRYTIM---PSGDLVITNAHA-EDENSMYHWTAVNTLTGETHASNPAKLVVVPSSSPFAP 474

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           +   +  +  +  G+     C   G P P   W  + + +       ++   S    LMI
Sbjct: 475 RMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIAGGS----LMI 530

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP-VVLN 511
            +   SD    TC A N  G       L VI     V   F ER      + G P   + 
Sbjct: 531 ESTMASDEANYTCQAVNNVGSVHMAIYLEVI-----VPITFKERPKPQAAQVGFPRKNME 585

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               G P P+ITW ++    +  P+ RI      + L I      D   YQC A N    
Sbjct: 586 CDVTGEPEPKITWYQN-AQSLGQPKGRISIRD--NDLVIATVYGQDNGVYQCVADNGREL 642

Query: 572 TATRARLY 579
             + A  Y
Sbjct: 643 VQSSAEFY 650



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 58/231 (25%), Positives = 89/231 (38%), Gaps = 17/231 (7%)

Query: 3569 LSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDA 3627
            + E    H+ C ++   D    + W  +GKPL +      I    F+  L I  V QR  
Sbjct: 856  VDEGQREHYTC-VVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914

Query: 3628 GLYTCKATNRHGEATVSCKLQV--KGRQGIILEPQL----PSHFKSGTESIQKLEETLHK 3681
            G+YTC   NR G A  S +L V    R   +L   L     S    G  S       +  
Sbjct: 915  GVYTCIVGNRAGIARHSAQLIVYDNHRFQQLLNGTLVIRNASKRDEGRYSCHAYNGVVGT 974

Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
                 +     + P   V    +  V   G + F C    +G+  + + WF+  +     
Sbjct: 975  PVSRQV-SLVVHVPAVIVSPPSDRSVEVFGEMAFSC--VAIGNLPIMLSWFNGSKQMVDS 1031

Query: 3742 SRV----HTLNDFGFI--ALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            SRV    +T ++   +   L +  +   D  EY+CR  N++G    T KIT
Sbjct: 1032 SRVQIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKIT 1082



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 42/164 (25%), Positives = 67/164 (40%), Gaps = 20/164 (12%)

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            TL+I  A  +D G+Y C A N           VV  P ++      +   + P  I+ P 
Sbjct: 949  TLVIRNASKRDEGRYSCHAYNG----------VVGTPVSRQV----SLVVHVPAVIVSPP 994

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR-TADEY-----TLRIS 4683
             D+ V     + FSC  +G     + W+ G K +  S   Q+ R T D       TL +S
Sbjct: 995  SDRSVEVFGEMAFSCVAIGNLPIMLSWFNGSKQMVDSSRVQIMRYTKDNAHLVNGTLHVS 1054

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            +    D  +Y C   N  GR     K+ V +     ++P ++ +
Sbjct: 1055 DLRLWDTKEYSCRVGNQFGRDEKTFKITVQESPSNPSVPRVSDI 1098



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 42/152 (27%), Positives = 61/152 (40%), Gaps = 12/152 (7%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            VI W  +G+TI    R     +     L I   + +DSG Y+C A N  G+ + SV +  
Sbjct: 786  VITWSRSGQTIPYDRR----QSIDNGTLLIGNVQKSDSGKYTCTAVNTAGERD-SVTMTV 840

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
               S    PR T  +     + +GQ  H+ C V   D P   I W  +G+P+        
Sbjct: 841  ---SIVVSPRITPFMW--APVDEGQREHYTCVVAEGDMP-CNITWLRDGKPLYSIPGDLE 894

Query: 3201 VSDFGFV-VLDIAYTQNHDSGEYVCRAYNKYG 3231
            +    F+  L I        G Y C   N+ G
Sbjct: 895  IMTSQFISSLSIPQVMQRHQGVYTCIVGNRAG 926



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP       +    QG       + +G P PV++W+R    +     Y  R +   G  +
Sbjct: 755 PPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTI----PYDRRQSIDNG--T 808

Query: 131 LLIKQIGPGDEGEYTCTARNQYGE 154
           LLI  +   D G+YTCTA N  GE
Sbjct: 809 LLIGNVQKSDSGKYTCTAVNTAGE 832



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P++     N  L  G  A  Q   +G+P P   W K+G+ L    +  +I      +L +
Sbjct: 474 PRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVIA---GGSLMI 530

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            +T  SD  +YT  A N  G +  + YL V  P
Sbjct: 531 ESTMASDEANYTCQAVNNVGSVHMAIYLEVIVP 563



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 36/116 (31%), Positives = 52/116 (44%), Gaps = 12/116 (10%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            DSG Y C A+N  G AE  +K+      +G  P  T+   ++ G++ G +    C     
Sbjct: 729  DSGEYKCVASNAAGSAEQVIKVYV----RGP-PNITSFRSSVTGVQ-GDTISLPCRAKGF 782

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
              P   I W  +GQ + +  R     D G ++  I   Q  DSG+Y C A N  GE
Sbjct: 783  PPP--VITWSRSGQTIPYDRRQSI--DNGTLL--IGNVQKSDSGKYTCTAVNTAGE 832



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP I     +    +G       +  G P P +TW ++GQ +    +  I    ++ TL 
Sbjct: 755 PPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTIPYDRRQSI----DNGTLL 810

Query: 325 VRNTQKSDSGHYTLLAENPNG 345
           + N QKSDSG YT  A N  G
Sbjct: 811 IGNVQKSDSGKYTCTAVNTAG 831



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 6/94 (6%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            APR  + ++  T ++ G++A  +C     P P  R  W  +GK L  G R          
Sbjct: 473  APRMTSLVHNLTLIA-GETAVLQCTAAGSPTPYFR--WLKSGKSLTMGGRMSV---IAGG 526

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            +L I +    D   YTC+A+NN+G    +I L V
Sbjct: 527  SLMIESTMASDEANYTCQAVNNVGSVHMAIYLEV 560



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 5/79 (6%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G+   L+C     G PT    W  +G+S+T+G R          +L I    ++D   YT
Sbjct: 488  GETAVLQCTAA--GSPTPYFRWLKSGKSLTMGGRMSV---IAGGSLMIESTMASDEANYT 542

Query: 1252 VRAVNHLGSAHTSAIVRVI 1270
             +AVN++GS H +  + VI
Sbjct: 543  CQAVNNVGSVHMAIYLEVI 561



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 61/267 (22%), Positives = 100/267 (37%), Gaps = 27/267 (10%)

Query: 3678 TLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRP 3737
            T  +R+ +T+       PR T  +   +D  EG   H+ C V   GD    I W  +G+P
Sbjct: 829  TAGERDSVTMTVSIVVSPRITPFMWAPVD--EGQREHYTCVVAE-GDMPCNITWLRDGKP 885

Query: 3738 -FATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
             ++    +  +      +L I  +  R  G YTC   N+ G A  +A++           
Sbjct: 886  LYSIPGDLEIMTSQFISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQLIVYDNHRF--- 942

Query: 3797 SQLPQG-MSGEKIKELERGRIS--------DAPKEEP---IVSTPPKFITQIKSHTVEES 3844
             QL  G +      + + GR S          P       +V  P   ++     +VE  
Sbjct: 943  QQLLNGTLVIRNASKRDEGRYSCHAYNGVVGTPVSRQVSLVVHVPAVIVSPPSDRSVEVF 1002

Query: 3845 EGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHR---YRTVYDMGFV---SLDILYVYAED 3898
              + F C V     P + + W+   K +    R    R   D   +   +L +  +   D
Sbjct: 1003 GEMAFSC-VAIGNLP-IMLSWFNGSKQMVDSSRVQIMRYTKDNAHLVNGTLHVSDLRLWD 1060

Query: 3899 SGEYICRAVNDFGEDFTKATISCKKLP 3925
            + EY CR  N FG D     I+ ++ P
Sbjct: 1061 TKEYSCRVGNQFGRDEKTFKITVQESP 1087



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 5/94 (5%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+ +  +HN+  + G    L+C     G  T    W  +GK +  G R          +
Sbjct: 473  APRMTSLVHNLTLIAGETAVLQC--TAAGSPTPYFRWLKSGKSLTMGGRMS---VIAGGS 527

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            L + S    D   YTCQA N +G    +  L VI
Sbjct: 528  LMIESTMASDEANYTCQAVNNVGSVHMAIYLEVI 561



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 53/237 (22%), Positives = 88/237 (37%), Gaps = 22/237 (9%)

Query: 1589 IKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVA-LDIMSCLPEDS 1647
            + EGQR H+   ++   D    + W  + KPL S     E     F++ L I   +    
Sbjct: 856  VDEGQREHYTC-VVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914

Query: 1648 GTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRH------- 1700
            G YTC   N  G A  S   IV+     + +  +   + R     D  +Y  H       
Sbjct: 915  GVYTCIVGNRAGIARHSAQLIVYDNHR-FQQLLNGTLVIRNASKRDEGRYSCHAYNGVVG 973

Query: 1701 ---SAQDEVITQAP-VFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEAS 1756
               S Q  ++   P V   P  D  V       F    + +G+  + + W      +  S
Sbjct: 974  TPVSRQVSLVVHVPAVIVSPPSDRSVEVFGEMAFSC--VAIGNLPIMLSWFNGSKQMVDS 1031

Query: 1757 NRLTTMH---DFGYV---ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
            +R+  M    D  ++    L++  +   D+  Y+CR  N+ G    +  + VQ   S
Sbjct: 1032 SRVQIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQESPS 1088



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 4442 IKWYRENFPIKNSP-DFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
            I W R+  P+ + P D +I T    S L I QV      V+  +  NR G A+ SA L+V
Sbjct: 877  ITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQLIV 936

Query: 4501 EEKRR 4505
             +  R
Sbjct: 937  YDNHR 941



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 35/103 (33%), Positives = 45/103 (43%), Gaps = 7/103 (6%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP   +   S T  + + +   CR   K  P   I W R+G+ +P   R     D G
Sbjct: 752  VRGPPNITSFRSSVTGVQGDTISLPCRA--KGFPPPVITWSRSGQTIPYDRRQSI--DNG 807

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGE-DFTKATISCKKLPDI 3927
              +L I  V   DSG+Y C AVN  GE D    T+S    P I
Sbjct: 808  --TLLIGNVQKSDSGKYTCTAVNTAGERDSVTMTVSIVVSPRI 848



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 5/94 (5%)

Query: 69  PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
           P  P    +  N     G  A  +    G+PTP   W +    L    + S+        
Sbjct: 471 PFAPRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSV-----IAG 525

Query: 129 VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
            SL+I+     DE  YTC A N  G    ++Y++
Sbjct: 526 GSLMIESTMASDEANYTCQAVNNVGSVHMAIYLE 559



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 6/94 (6%)

Query: 3685 ITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV 3744
            + +    P  PR T  +  N+ +  G      C     G PT    W  +G+    G R+
Sbjct: 464  VVVPSSSPFAPRMT-SLVHNLTLIAGETAVLQCTA--AGSPTPYFRWLKSGKSLTMGGRM 520

Query: 3745 HTLNDFGFIALDIDYIYARDAGEYTCRATNKWGS 3778
              +      +L I+   A D   YTC+A N  GS
Sbjct: 521  SVIAGG---SLMIESTMASDEANYTCQAVNNVGS 551



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 7/93 (7%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRY------RTSNDFGFAALDILTV 1909
            L  G      C +   P P   V+WY +   L  GH Y       T      + L    V
Sbjct: 667  LYPGTPLQITCEVSAIPYPR-DVQWYHDDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAV 725

Query: 1910 YGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
               DSGEY C A N  G A   I++ V+   +I
Sbjct: 726  SMADSGEYKCVASNAAGSAEQVIKVYVRGPPNI 758



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 6/86 (6%)

Query: 1842 QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            + P  IT         +G +    CR + +P P   + W  +G+ +    R    N    
Sbjct: 753  RGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPV--ITWSRSGQTIPYDRRQSIDN---- 806

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQ 1927
              L I  V   DSG+YTC A+N  G+
Sbjct: 807  GTLLIGNVQKSDSGKYTCTAVNTAGE 832



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 9/101 (8%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP       SVT ++G  I    R +  G P   I W ++GQ+I    R  SI   G + 
Sbjct: 755 PPNITSFRSSVTGVQGDTISLPCRAK--GFPPPVITWSRSGQTIPYDRR-QSIDN-GTLL 810

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAV---LHVTPRAT 733
           +   ++   DSG+YTC AV+  G  ++  +   + V+PR T
Sbjct: 811 IG--NVQKSDSGKYTCTAVNTAGERDSVTMTVSIVVSPRIT 849



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 4/82 (4%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G PT    WLK+G+S+    R  S+   G  SL + S    D   YTC+AV+  G     
Sbjct: 499 GSPTPYFRWLKSGKSLTMGGRM-SVIAGG--SLMIESTMASDEANYTCQAVNNVGSVHMA 555

Query: 724 AVLHVTPRATIERTSQHPETLQ 745
             L V    T +   + P+  Q
Sbjct: 556 IYLEVIVPITFKERPK-PQAAQ 576



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 3/60 (5%)

Query: 793 QLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852
           Q T    PT    W K G+ +T   R+ S+   G  SL I    A D  +YT +AVN +G
Sbjct: 494 QCTAAGSPTPYFRWLKSGKSLTMGGRM-SVIAGG--SLMIESTMASDEANYTCQAVNNVG 550



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 6/100 (6%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQ-FQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           + P    ++P+    Q G   +  +  ++G P P++TW++N Q L    K  I    N  
Sbjct: 561 IVPITFKERPKPQAAQVGFPRKNMECDVTGEPEPKITWYQNAQSL-GQPKGRISIRDN-- 617

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSG--YLAVESPT 359
            L +      D+G Y  +A+N    + +S   Y     PT
Sbjct: 618 DLVIATVYGQDNGVYQCVADNGRELVQSSAEFYAGFSVPT 657



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 9/101 (8%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            + P   T  +S    V+G  + L  + +    P   I W ++G T+    R   + D G 
Sbjct: 753  RGPPNITSFRSSVTGVQGDTISLPCRAKGFPPP--VITWSRSGQTIPYDRR--QSIDNG- 807

Query: 2700 VTLSINSLRNDDSGIYTCKATNLLGEAVS---TASIKIEDR 2737
             TL I +++  DSG YTC A N  GE  S   T SI +  R
Sbjct: 808  -TLLIGNVQKSDSGKYTCTAVNTAGERDSVTMTVSIVVSPR 847



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 49/235 (20%), Positives = 90/235 (38%), Gaps = 17/235 (7%)

Query: 921  IKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV-ALTIKSVTVHDA 979
            + EG   H+   +   GD    + WL+DG+P+ +           ++ +L+I  V     
Sbjct: 856  VDEGQREHYTCVVAE-GDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914

Query: 980  GHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKI 1039
            G YTC   N  G A  SA L IV       +  +   + +     D  RYS      V  
Sbjct: 915  GVYTCIVGNRAGIARHSAQL-IVYDNHRFQQLLNGTLVIRNASKRDEGRYSCHAYNGVVG 973

Query: 1040 TQKPRFLGPLKGTNKIVEGQSAHFEARVEPQ--------SDLTMTVEWYFNGKQITSANR 1091
            T   R +  +     ++    +     V  +         +L + + W+   KQ+  ++R
Sbjct: 974  TPVSRQVSLVVHVPAVIVSPPSDRSVEVFGEMAFSCVAIGNLPIMLSWFNGSKQMVDSSR 1033

Query: 1092 IQTYH---DFGYV---ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
            +Q      D  ++    L ++ +R  D+  Y+    N  G  + +  +TV+   S
Sbjct: 1034 VQIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQESPS 1088



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 49/233 (21%), Positives = 89/233 (38%), Gaps = 21/233 (9%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA-LDLLSVYPEDSGV 1382
            EG   H  C +   GD    + W  +GKP+ +           +++ L +  V     GV
Sbjct: 858  EGQREHYTCVVAE-GDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQGV 916

Query: 1383 YTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYK---KTDIIDES 1439
            YTC   N+ G A  S  L ++       +  + + + +     D  RY       ++   
Sbjct: 917  YTCIVGNRAGIARHSAQL-IVYDNHRFQQLLNGTLVIRNASKRDEGRYSCHAYNGVVGTP 975

Query: 1440 VTIK-------PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            V+ +       P  +  P S  +V     + F C    + +  + + WF   + +    R
Sbjct: 976  VSRQVSLVVHVPAVIVSPPSDRSVEVFGEMAFSC--VAIGNLPIMLSWFNGSKQMVDSSR 1033

Query: 1493 ---FRPIHDFGYV---ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
                R   D  ++    L + DL   D+  Y+CR  N  G DE + ++T + +
Sbjct: 1034 VQIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQES 1086



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 8/120 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG------SRVHTLN 3748
            P F     D I  P G P+   C V  +  P   + W+H+  P   G      +   T  
Sbjct: 656  PTFNPGTPDIILYP-GTPLQITCEVSAIPYPR-DVQWYHDDIPLTGGHDYIITAMPGTKR 713

Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
                  L    +   D+GEY C A+N  GSA    K+      +I        G+ G+ I
Sbjct: 714  SSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVYVRGPPNITSFRSSVTGVQGDTI 773



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYK 4158
            EQV++    R PP   S   +VT  +G+     CR  G P P + W  +G TI    R  
Sbjct: 745  EQVIKVY-VRGPPNITSFRSSVTGVQGDTISLPCRAKGFPPPVITWSRSGQTIPYDRRQS 803

Query: 4159 LTYDGMYHFDIPKTRQYDTGK 4179
            +    +   ++ K+   D+GK
Sbjct: 804  IDNGTLLIGNVQKS---DSGK 821



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 2/89 (2%)

Query: 1722 VAENQAAHFEARLIPVGDPKLRVEWLRNGVPI-EASNRLTTMHDFGYVALNMKYVNPEDS 1780
            V E Q  H+   ++  GD    + WLR+G P+      L  M      +L++  V     
Sbjct: 856  VDEGQREHYTC-VVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914

Query: 1781 GTYTCRAINELGEAVTSSTLFVQSKASLQ 1809
            G YTC   N  G A  S+ L V      Q
Sbjct: 915  GVYTCIVGNRAGIARHSAQLIVYDNHRFQ 943



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 49/230 (21%), Positives = 84/230 (36%), Gaps = 16/230 (6%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPEDSGE 3492
            EG+  H+   +   D P   + W  +GK L +           F+  L I        G 
Sbjct: 858  EGQREHYTCVVAEGDMP-CNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQGV 916

Query: 3493 YLCRAYNNYGEAVTTASMKVQGKRNI--ILESQLPKGMEGTIDKIA-ALEGYSGTVDTLT 3549
            Y C   N  G A  +A + V        +L   L        D+   +   Y+G V T  
Sbjct: 917  YTCIVGNRAGIARHSAQLIVYDNHRFQQLLNGTLVIRNASKRDEGRYSCHAYNGVVGTPV 976

Query: 3550 PEAES---GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRV 3606
                S     P    + PSD  +       F C  + + +  + + WF+  K ++  SRV
Sbjct: 977  SRQVSLVVHVPAVIVSPPSDRSVEVFGEMAFSC--VAIGNLPIMLSWFNGSKQMVDSSRV 1034

Query: 3607 KTI---NDFGFVI---LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            + +    D   ++   L +  +   D   Y+C+  N+ G    + K+ V+
Sbjct: 1035 QIMRYTKDNAHLVNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQ 1084



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 4/79 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPS--GTRYKSTHDFSYVSLDITHTYEEDSG 2844
            EG   H+ C V    D    I W  + KPL S  G     T  F   SL I    +   G
Sbjct: 858  EGQREHYTCVVAEG-DMPCNITWLRDGKPLYSIPGDLEIMTSQF-ISSLSIPQVMQRHQG 915

Query: 2845 IYTCKATNSKGSATTSGSL 2863
            +YTC   N  G A  S  L
Sbjct: 916  VYTCIVGNRAGIARHSAQL 934



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 20/63 (31%), Positives = 27/63 (42%)

Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            VV  S +   P   SL   +T+  GE A   C   G P P   WL +G ++  G R  + 
Sbjct: 464  VVVPSSSPFAPRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFRWLKSGKSLTMGGRMSVI 523

Query: 4161 YDG 4163
              G
Sbjct: 524  AGG 526



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 6/84 (7%)

Query: 3419 APVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV 3478
            AP  T  + N+  L  GE A  +   T    P     W  +GKSL  G R       G +
Sbjct: 473  APRMTSLVHNL-TLIAGETAVLQC--TAAGSPTPYFRWLKSGKSLTMGGRMSVIAG-GSL 528

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYG 3502
            ++E   T   D   Y C+A NN G
Sbjct: 529  MIE--STMASDEANYTCQAVNNVG 550



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P+  F W  +G  L MG R          +L I S +A+D   Y C+A+N  G
Sbjct: 499  GSPTPYFRWLKSGKSLTMGGRMSV---IAGGSLMIESTMASDEANYTCQAVNNVG 550



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 7/101 (6%)

Query: 1293 DAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKP 1352
            +AA   +QV + + V   P  +    ++  V+G  + L CR +  G     + W  +G+ 
Sbjct: 739  NAAGSAEQVIK-VYVRGPPNITSFRSSVTGVQGDTISLPCRAK--GFPPPVITWSRSGQT 795

Query: 1353 IKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
            I    R       D   L + +V   DSG YTC A N  GE
Sbjct: 796  IPYDRR----QSIDNGTLLIGNVQKSDSGKYTCTAVNTAGE 832



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 2/72 (2%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS-MTISHVRDEDE 2446
            + EGQ  H+ C ++  GD    + W R+ K +       +     ++S ++I  V    +
Sbjct: 856  VDEGQREHYTC-VVAEGDMPCNITWLRDGKPLYSIPGDLEIMTSQFISSLSIPQVMQRHQ 914

Query: 2447 GVYMCRASNLLG 2458
            GVY C   N  G
Sbjct: 915  GVYTCIVGNRAG 926



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 18/118 (15%)

Query: 3545 VDTLTPEAESGNPPEFTTTPS-------------DLILSENSSAHFECRLIPVNDSSMRV 3591
            V+TLT E  + NP +    PS             +L L    +A  +C        +   
Sbjct: 448  VNTLTGETHASNPAKLVVVPSSSPFAPRMTSLVHNLTLIAGETAVLQC--TAAGSPTPYF 505

Query: 3592 EWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             W  +GK L  G R+  I   G +++E       D   YTC+A N  G   ++  L+V
Sbjct: 506  RWLKSGKSLTMGGRMSVIAG-GSLMIE--STMASDEANYTCQAVNNVGSVHMAIYLEV 560



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)

Query: 2625 AMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVT 2684
            A N    + V +    AP  T+ + +   L+ G+   L+        P  +  W K+G +
Sbjct: 457  ASNPAKLVVVPSSSPFAPRMTSLVHNLT-LIAGETAVLQCTAAGSPTPYFR--WLKSGKS 513

Query: 2685 LTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724
            LT G R+ S    G  +L I S    D   YTC+A N +G
Sbjct: 514  LTMGGRM-SVIAGG--SLMIESTMASDEANYTCQAVNNVG 550



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T    WLK G+ +    R++        +L I+S    D  +YTC+A N +G    +
Sbjct: 499  GSPTPYFRWLKSGKSLTMGGRMSVIAGG---SLMIESTMASDEANYTCQAVNNVGSVHMA 555

Query: 997  ANLTIV 1002
              L ++
Sbjct: 556  IYLEVI 561



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/61 (37%), Positives = 30/61 (49%), Gaps = 9/61 (14%)

Query: 1865 ECRIEPYPDPNMRVEWYFNGKVL--QSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAI 1922
            EC +   P+P  ++ WY N + L    G      ND     L I TVYG+D+G Y C A 
Sbjct: 585  ECDVTGEPEP--KITWYQNAQSLGQPKGRISIRDND-----LVIATVYGQDNGVYQCVAD 637

Query: 1923 N 1923
            N
Sbjct: 638  N 638



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 40/178 (22%), Positives = 74/178 (41%), Gaps = 18/178 (10%)

Query: 3850 ECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN- 3908
            EC V  + +PK  I WY+N + L       ++ D   V   I  VY +D+G Y C A N 
Sbjct: 585  ECDVTGEPEPK--ITWYQNAQSLGQPKGRISIRDNDLV---IATVYGQDNGVYQCVADNG 639

Query: 3909 --------DFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQMEATIKKYTSEVYLT 3960
                    +F   F+  T +    PDIIL    P  +    +       ++ Y  ++ LT
Sbjct: 640  RELVQSSAEFYAGFSVPTFN-PGTPDIILYPGTPLQITCEVSAIPYPRDVQWYHDDIPLT 698

Query: 3961 EDDLYDVDKKQPPRFVTQIQ--SQTSLVEMETTKFECQLA-PVGDPNMKVEWFFNGKP 4015
                Y +      +  +++   S+T++   ++ +++C  +   G     ++ +  G P
Sbjct: 699  GGHDYIITAMPGTKRSSRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVYVRGPP 756



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 6/101 (5%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS--GHRYRT 1895
            V++  +PR    +  P  + EGQ  HY C +     P   + W  +GK L S  G     
Sbjct: 840  VSIVVSPRITPFMWAP--VDEGQREHYTCVVAEGDMP-CNITWLRDGKPLYSIPGDLEIM 896

Query: 1896 SNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            ++ F  ++L I  V     G YTC   N  G A  S +L V
Sbjct: 897  TSQF-ISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQLIV 936



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-TIGHRFRPIH 1497
            S+ + PR    P     V EGQ  H+ C +    D    + W ++G+P+ +I      + 
Sbjct: 841  SIVVSPRIT--PFMWAPVDEGQREHYTCVVAE-GDMPCNITWLRDGKPLYSIPGDLEIMT 897

Query: 1498 DFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
                 +L I  ++    G+YTC   N  G    S +L
Sbjct: 898  SQFISSLSIPQVMQRHQGVYTCIVGNRAGIARHSAQL 934



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 6/96 (6%)

Query: 1432 KTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGH 1491
            K  ++  S    PR  +   ++  +I G+    +C          +  W K+G+ +T+G 
Sbjct: 462  KLVVVPSSSPFAPRMTSLVHNL-TLIAGETAVLQCTAAGSPTPYFR--WLKSGKSLTMGG 518

Query: 1492 RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527
            R   I      +L I   +A D   YTC+AVN VG+
Sbjct: 519  RMSVIAGG---SLMIESTMASDEANYTCQAVNNVGS 551



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 7/93 (7%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAE--- 2177
            L  G      C V  I  P   + W+H+   +  GH Y  T   G      L   +    
Sbjct: 667  LYPGTPLQITCEVSAIPYPR-DVQWYHDDIPLTGGHDYIITAMPGTKRSSRLSKLSRTAV 725

Query: 2178 ---DSGTYMCKATNKLGEAVNTCTLKVAGHRNI 2207
               DSG Y C A+N  G A     + V G  NI
Sbjct: 726  SMADSGEYKCVASNAAGSAEQVIKVYVRGPPNI 758



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 5/82 (6%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P+  + + + T+   E    +C       P  R  W ++GK L  G R   +      SL
Sbjct: 474  PRMTSLVHNLTLIAGETAVLQCTAAGSPTPYFR--WLKSGKSLTMGGRMSVIAGG---SL 528

Query: 3890 DILYVYAEDSGEYICRAVNDFG 3911
             I    A D   Y C+AVN+ G
Sbjct: 529  MIESTMASDEANYTCQAVNNVG 550



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 3/63 (4%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            +P+ KI WY N + L Q        D   V   +  VY +D+G+Y C A N R    +S+
Sbjct: 591  EPEPKITWYQNAQSLGQPKGRISIRDNDLV---IATVYGQDNGVYQCVADNGRELVQSSA 647

Query: 3000 TVY 3002
              Y
Sbjct: 648  EFY 650



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 10/100 (10%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  T   + ++   +G  +   CR +  G P   I W  +G+      R    N     
Sbjct: 755  PPNIT-SFRSSVTGVQGDTISLPCRAK--GFPPPVITWSRSGQTIPYDRRQSIDNG---- 807

Query: 3754 ALDIDYIYARDAGEYTCRATNKWG---SATTTAKITCSAK 3790
             L I  +   D+G+YTC A N  G   S T T  I  S +
Sbjct: 808  TLLIGNVQKSDSGKYTCTAVNTAGERDSVTMTVSIVVSPR 847



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 7/96 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRY-----KSTHDFSYVS-LDI 2835
            +I+   G  +   C V     P   ++W+ ++ PL  G  Y       T   S +S L  
Sbjct: 664  DIILYPGTPLQITCEVSAIPYPR-DVQWYHDDIPLTGGHDYIITAMPGTKRSSRLSKLSR 722

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNI 2871
            T     DSG Y C A+N+ GSA     +   G  NI
Sbjct: 723  TAVSMADSGEYKCVASNAAGSAEQVIKVYVRGPPNI 758



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 5/61 (8%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
            +P+ K+ W+ N + L       +  D  +VI  +   Y +++G Y+CVA N  GR+  ++
Sbjct: 591  EPEPKITWYQNAQSLGQPKGRISIRDNDLVIATV---YGQDNGVYQCVADN--GRELVQS 645

Query: 3371 N 3371
            +
Sbjct: 646  S 646



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 5/81 (6%)

Query: 3972 PPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV 4031
            P  F  + + Q + V       EC +   G+P  K+ W+ N + L        I D   V
Sbjct: 563  PITFKERPKPQAAQVGFPRKNMECDVT--GEPEPKITWYQNAQSLGQPKGRISIRDNDLV 620

Query: 4032 AMNFGWVYPEDSGEYLCRATN 4052
                  VY +D+G Y C A N
Sbjct: 621  IAT---VYGQDNGVYQCVADN 638



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 27/104 (25%), Positives = 39/104 (37%), Gaps = 7/104 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTG------SRVKTIND 3611
            P F     D+IL   +     C +  +      V+W+H+  PL  G      +   T   
Sbjct: 656  PTFNPGTPDIILYPGTPLQITCEVSAI-PYPRDVQWYHDDIPLTGGHDYIITAMPGTKRS 714

Query: 3612 FGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGI 3655
                 L    V   D+G Y C A+N  G A    K+ V+G   I
Sbjct: 715  SRLSKLSRTAVSMADSGEYKCVASNAAGSAEQVIKVYVRGPPNI 758



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 6/84 (7%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P  +T+  S     +GD     CR +    P +T  W  +GQ I   +  R + D G   
Sbjct: 755  PPNITSFRSSVTGVQGDTISLPCRAKGFPPPVIT--WSRSGQTIP--YDRRQSIDNG--T 808

Query: 2169 LDILYTYAEDSGTYMCKATNKLGE 2192
            L I      DSG Y C A N  GE
Sbjct: 809  LLIGNVQKSDSGKYTCTAVNTAGE 832


>SB_40832| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1496

 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 85/361 (23%), Positives = 144/361 (39%), Gaps = 33/361 (9%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L++R V   DS  +  +A N  G A  S  + V +                  ++ N   
Sbjct: 352  LVLRNVMSSDSGNYTCIASNVVGRASASTMVNVTDPIMPSIARATSDHIATQPESANQDI 411

Query: 4528 GQLVRLDT--------KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQ 4579
            G+ + L T          TG     V W +  + +     + ++   GT +L IL   P 
Sbjct: 412  GKSIVLLTGSSLVLHCNATGHPQPVVTWRRGSQPISGLADHTLI---GT-SLRILNLEPA 467

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVA-EGQ 4638
            D  +Y C A N  G+A    E  V   +  +    +T+  N   ++  P+   +   +  
Sbjct: 468  DMEEYTCTASNVGGKAAASTELTVKALSKPNIKTVRTRINNVRRDVTVPIGTTLTTIQNS 527

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
             +  +C   G P P + W+K  + I P   ++ + T+    L I +  P DEG Y C A 
Sbjct: 528  TVVITCPTEGFPKPIISWFKDGEPITPDLKYEANCTS----LIIRDIQPGDEGSYTCTAV 583

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPA---LTPLRD---------IVVYEGQPAQFKTQITS 4746
            N  G       + VT+P    N+     +T +R+         + +  G     + ++T 
Sbjct: 584  NPMGTDVNNMSITVTKPPVIINVKGSFEVTDIRELLSITTGAIVTIPRGVTITIRCEVTG 643

Query: 4747 KIKPTIQWLR--EGALIPE--TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
            K +P I W R  EG+   +  TP  + +H  ++  L I  T + D   + C AT  AG+ 
Sbjct: 644  KPEPNITWYRIPEGSQRWQLITPLDRYMHLRSDMSLAIDRTAQVDAAQYVCVATNIAGRD 703

Query: 4803 E 4803
            E
Sbjct: 704  E 704



 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 72/264 (27%), Positives = 107/264 (40%), Gaps = 36/264 (13%)

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
           TL +R  + +DSG YT  A N  G    S  + V  P++             T +R    
Sbjct: 12  TLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKP------------TIERPVAP 59

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
           R +I     +P   ++  +  V  G     DC  TG P P + W  + R++    ++   
Sbjct: 60  R-DIPLGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMA- 117

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK--EQVVAPKFVERFST 499
               GN +L+I  V  S  GV TC A N  GE +    + V++    ++  P      ST
Sbjct: 118 ---PGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRISRPTIGSTKST 174

Query: 500 LNVR-------------EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
            N+              EG  V +   A G P P + W KDG+ + P     +       
Sbjct: 175 DNMNPVSISVGSDVTAIEGVTVSIECNATGVPRPEVFWSKDGLRLYPGEYPVLEN----K 230

Query: 547 TLDIPRAKASDAAWYQCTAQNVAG 570
           TL I  AK  D+ +Y CTAQ+  G
Sbjct: 231 TLIITNAKVDDSGYYTCTAQSSIG 254



 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 82/319 (25%), Positives = 132/319 (41%), Gaps = 40/319 (12%)

Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
           EG     +   +G PRP V W K+G RL    ++ ++    + TL + N +  DSG+YT 
Sbjct: 192 EGVTVSIECNATGVPRPEVFWSKDGLRLY-PGEYPVL---ENKTLIITNAKVDDSGYYTC 247

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQD--QRSQYITDTQQ----RETEERIEISEKALAP 392
            A++  G    S  + +    +S +       +Y     +    + T +++E S+  + P
Sbjct: 248 TAQSSIGKDSQSSVVEILRDKQSRLVFGVMSLKYSFSAAEVPIIQRTTDKVEKSD--MKP 305

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
             V++        G     +C   G P P++ W           N   ++   G   L++
Sbjct: 306 VDVRIGGQVTSLSGVDITLNCSARGLPPPDIEWM----------NGGKMITVQGPR-LVL 354

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK-EQVVAPKFVERFST------------ 499
            NV  SDSG  TC+A N  G  +    +NV +     +A    +  +T            
Sbjct: 355 RNVMSSDSGNYTCIASNVVGRASASTMVNVTDPIMPSIARATSDHIATQPESANQDIGKS 414

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
           + +  G  +VL+  A G P P +TW++   PI     L  HT  G S L I   + +D  
Sbjct: 415 IVLLTGSSLVLHCNATGHPQPVVTWRRGSQPI---SGLADHTLIGTS-LRILNLEPADME 470

Query: 560 WYQCTAQNVAGSTATRARL 578
            Y CTA NV G  A    L
Sbjct: 471 EYTCTASNVGGKAAASTEL 489



 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 77/284 (27%), Positives = 114/284 (40%), Gaps = 28/284 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P++ W R + PI    D   HT    S+ I+  +   D   +   A N GG A  S
Sbjct: 431  GHPQPVVTWRRGSQPISGLAD---HTLIGTSLRIL-NLEPADMEEYTCTASNVGGKAAAS 486

Query: 4496 ANLVVEE------KRRQGRGGIVPPSFTL-TAQNVNVTSGQLVRLDTKVTG-TKPIDVYW 4547
              L V+       K  + R   V    T+     +       V +     G  KPI + W
Sbjct: 487  TELTVKALSKPNIKTVRTRINNVRRDVTVPIGTTLTTIQNSTVVITCPTEGFPKPI-ISW 545

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             K+G+ + PD++     E    +L+I +  P D G Y C A+N  G    +    V+ P 
Sbjct: 546  FKDGEPITPDLK----YEANCTSLIIRDIQPGDEGSYTCTAVNPMGTDVNNMSITVTKPP 601

Query: 4608 TKDKPKPQTKAANAPPEIIEPLKDKIVA--EGQAIEFSCKIVGKPLPTVQWYK---GD-- 4660
                 K   +  +   E++      IV    G  I   C++ GKP P + WY+   G   
Sbjct: 602  VIINVKGSFEVTDI-RELLSITTGAIVTIPRGVTITIRCEVTGKPEPNITWYRIPEGSQR 660

Query: 4661 -KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
             +LI P   +   R+  + +L I      D   Y CVA N AGR
Sbjct: 661  WQLITPLDRYMHLRS--DMSLAIDRTAQVDAAQYVCVATNIAGR 702



 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 65/265 (24%), Positives = 105/265 (39%), Gaps = 21/265 (7%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANL-VVEEKRRQGRGGIVP---------PSFT 4517
            L++R+    DS  +   A N  G    S+ + V+E  +      + P         P+  
Sbjct: 13   LVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAPRDIPLGDGSPTIA 72

Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577
              A N  V +G  + +D   TG     + W K+G+++   I        G  +LLI +  
Sbjct: 73   RIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGREL---IGAGSYMAPGNGSLLIQQVA 129

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP---QTKAA-NAPPEIIEPLKDKI 4633
                G + C A N  GE    +   V  P      +P    TK+  N  P  I    D  
Sbjct: 130  ASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRISRPTIGSTKSTDNMNPVSISVGSDVT 189

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
              EG  +   C   G P P V W K    + P +Y       +  TL I+ A  +D G Y
Sbjct: 190  AIEGVTVSIECNATGVPRPEVFWSKDGLRLYPGEY----PVLENKTLIITNAKVDDSGYY 245

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQA 4718
             C A +S G+ + ++ +++ +  Q+
Sbjct: 246  TCTAQSSIGKDSQSSVVEILRDKQS 270



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 62/257 (24%), Positives = 104/257 (40%), Gaps = 28/257 (10%)

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP----QTKAANAPPEI 4625
            TL++  A P DSG+Y C A NS G+    ++  V  P+     +P         +  P I
Sbjct: 12   TLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAPRDIPLGDGSPTI 71

Query: 4626 IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISE 4684
                 +  V  G  +   C   G P P++ W K G +LI    Y      +    L I +
Sbjct: 72   ARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMAPGNGS----LLIQQ 127

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP-------------DQADNLP--ALTPLRD 4729
                  G + C A N  G  +V++ ++V  P                DN+   +++   D
Sbjct: 128  VAASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRISRPTIGSTKSTDNMNPVSISVGSD 187

Query: 4730 IVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            +   EG     +   T   +P + W ++G  +   P    + E  N  L+I N   +D+G
Sbjct: 188  VTAIEGVTVSIECNATGVPRPEVFWSKDGLRL--YPGEYPVLE--NKTLIITNAKVDDSG 243

Query: 4790 TFTCRATTAAGQVETSA 4806
             +TC A ++ G+   S+
Sbjct: 244  YYTCTAQSSIGKDSQSS 260



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 112/476 (23%), Positives = 170/476 (35%), Gaps = 69/476 (14%)

Query: 4384 STETTEIEHKAQTQERVV---EGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLP 4440
            S++   IE    T ER V   + P+    P I  +      V    +   +    G P P
Sbjct: 40   SSQVKVIEPSKPTIERPVAPRDIPLGDGSPTI-ARIADNATVLTGSRLTIDCVATGVPKP 98

Query: 4441 LIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             I W ++   +  +  +          L+I+QV      VF   A N  G    S+N+ V
Sbjct: 99   SIIWRKDGRELIGAGSYMA---PGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRV 155

Query: 4501 EEK--RRQGRGGI--------VPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKN 4550
             +    R  R  I        + P       +V    G  V ++   TG    +V+W K+
Sbjct: 156  VDPVLPRISRPTIGSTKSTDNMNPVSISVGSDVTAIEGVTVSIECNATGVPRPEVFWSKD 215

Query: 4551 GKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG--------EARCDAEC- 4601
            G ++ P     +LE     TL+I  A   DSG Y C A +S G        E   D +  
Sbjct: 216  GLRLYPG-EYPVLENK---TLIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDKQSR 271

Query: 4602 ----VVSLP---ATKDKPKPQTKAANAPPEIIEPLKDKIVAE-----GQAIEFSCKIVGK 4649
                V+SL    +  + P  Q          ++P+  +I  +     G  I  +C   G 
Sbjct: 272  LVFGVMSLKYSFSAAEVPIIQRTTDKVEKSDMKPVDVRIGGQVTSLSGVDITLNCSARGL 331

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P P ++W  G K+I          T     L +      D G+Y C+A N  GR + +  
Sbjct: 332  PPPDIEWMNGGKMI----------TVQGPRLVLRNVMSSDSGNYTCIASNVVGRASASTM 381

Query: 4710 LKVTQP----------DQADNLPALTPL---RDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
            + VT P          D     P        + IV+  G         T   +P + W R
Sbjct: 382  VNVTDPIMPSIARATSDHIATQPESANQDIGKSIVLLTGSSLVLHCNATGHPQPVVTWRR 441

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
                I    D  +I       L I N    D   +TC A+   G+   S +L VK+
Sbjct: 442  GSQPISGLADHTLI----GTSLRILNLEPADMEEYTCTASNVGGKAAASTELTVKA 493



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 79/304 (25%), Positives = 113/304 (37%), Gaps = 46/304 (15%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
           G D        G P P + W  NG ++I      ++         +RN   SDSG+YT +
Sbjct: 319 GVDITLNCSARGLPPPDIEWM-NGGKMITVQGPRLV---------LRNVMSSDSGNYTCI 368

Query: 340 AENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQ 399
           A N  G    S  + V  P    +    S +I  TQ     + I  S   L         
Sbjct: 369 ASNVVGRASASTMVNVTDPIMPSIARATSDHIA-TQPESANQDIGKSIVLLT-------- 419

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
                 G      C  TG P P VTW    + I    +H ++       +L I N+  +D
Sbjct: 420 ------GSSLVLHCNATGHPQPVVTWRRGSQPISGLADHTLI-----GTSLRILNLEPAD 468

Query: 460 SGVVTCVARNKSGETAFQCRLNV--IEKEQVVAPKF----------VERFSTLNVREGEP 507
               TC A N  G+ A    L V  + K  +   +           V   +TL   +   
Sbjct: 469 MEEYTCTASNVGGKAAASTELTVKALSKPNIKTVRTRINNVRRDVTVPIGTTLTTIQNST 528

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           VV+     G P P I+W KDG PI P+    +  +   ++L I   +  D   Y CTA N
Sbjct: 529 VVITCPTEGFPKPIISWFKDGEPITPD----LKYEANCTSLIIRDIQPGDEGSYTCTAVN 584

Query: 568 VAGS 571
             G+
Sbjct: 585 PMGT 588



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 138/573 (24%), Positives = 228/573 (39%), Gaps = 112/573 (19%)

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L I +  V D+G+YTC A ++IG+ + S+ + I+  K    +S+   G+  ++Y   A+ 
Sbjct: 232  LIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDK----QSRLVFGVMSLKYSFSAAE 287

Query: 1029 YS--KRTEEEV-KITQKP---RFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFN 1082
                +RT ++V K   KP   R  G +   + +    + +  AR  P  D    +EW   
Sbjct: 288  VPIIQRTTDKVEKSDMKPVDVRIGGQVTSLSGV--DITLNCSARGLPPPD----IEWMNG 341

Query: 1083 GKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSID 1142
            GK IT               L + +V + DSG YT +A N  G A  SAS  V     I 
Sbjct: 342  GKMITVQG----------PRLVLRNVMSSDSGNYTCIASNVVGRA--SASTMVNVTDPI- 388

Query: 1143 TSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLE 1202
              SI R   +   HI      +P    ++I KS  +             G ++ L C   
Sbjct: 389  MPSIARATSD---HIA----TQPESANQDIGKSIVLLT-----------GSSLVLHC--N 428

Query: 1203 PMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLG--S 1260
              G P   V W    + ++ G    T       +L I++   AD  EYT  A N  G  +
Sbjct: 429  ATGHPQPVVTWRRGSQPIS-GLADHTLIG---TSLRILNLEPADMEEYTCTASNVGGKAA 484

Query: 1261 AHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNI 1320
            A T   V+ + + +I T                   R   VR D+TV            +
Sbjct: 485  ASTELTVKALSKPNIKT----------------VRTRINNVRRDVTVPIGT-------TL 521

Query: 1321 ETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDS 1380
             T++ + V + C  +  G     + WF +G+PI    +    YE +  +L +  + P D 
Sbjct: 522  TTIQNSTVVITCPTE--GFPKPIISWFKDGEPITPDLK----YEANCTSLIIRDIQPGDE 575

Query: 1381 GVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESV 1440
            G YTC A N +G  V + ++  + K  +I+  +                ++ TDI +   
Sbjct: 576  GSYTCTAVNPMGTDVNNMSI-TVTKPPVIINVK--------------GSFEVTDIRELLS 620

Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG 1500
                  VT P+       G  +   C++    + N  + W++  +         P+  + 
Sbjct: 621  ITTGAIVTIPR-------GVTITIRCEVTGKPEPN--ITWYRIPEGSQRWQLITPLDRYM 671

Query: 1501 YVALDI---IDLIAE-DSGIYTCRAVNLVGTDE 1529
            ++  D+   ID  A+ D+  Y C A N+ G DE
Sbjct: 672  HLRSDMSLAIDRTAQVDAAQYVCVATNIAGRDE 704



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 74/313 (23%), Positives = 121/313 (38%), Gaps = 47/313 (15%)

Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
           L  G+        +G+P+P VTW +  Q +     H +I T    +LR+ N + +D   Y
Sbjct: 417 LLTGSSLVLHCNATGHPQPVVTWRRGSQPISGLADHTLIGT----SLRILNLEPADMEEY 472

Query: 337 TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
           T  A N  G    S  L V++ ++  ++  R++ I + ++  T               V 
Sbjct: 473 TCTASNVGGKAAASTELTVKALSKPNIKTVRTR-INNVRRDVT---------------VP 516

Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
           +       +       C   G P P ++WF +   I  D  +     E+   +L+I ++ 
Sbjct: 517 IGTTLTTIQNSTVVITCPTEGFPKPIISWFKDGEPITPDLKY-----EANCTSLIIRDIQ 571

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE------------ 504
             D G  TC A N  G       + V +   ++  K    F   ++RE            
Sbjct: 572 PGDEGSYTCTAVNPMGTDVNNMSITVTKPPVIINVK--GSFEVTDIRELLSITTGAIVTI 629

Query: 505 --GEPVVLNARAVGTPTPRITWQK--DGVP---IIPNPELRIHTDGGASTLDIPRAKASD 557
             G  + +     G P P ITW +  +G     +I   +  +H     S L I R    D
Sbjct: 630 PRGVTITIRCEVTGKPEPNITWYRIPEGSQRWQLITPLDRYMHLRSDMS-LAIDRTAQVD 688

Query: 558 AAWYQCTAQNVAG 570
           AA Y C A N+AG
Sbjct: 689 AAQYVCVATNIAG 701



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 60/231 (25%), Positives = 96/231 (41%), Gaps = 22/231 (9%)

Query: 257 DRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIIT 316
           D  LG  SP  IA+   N+ +  G+        +G P+P + W K+G+ LI +  +    
Sbjct: 61  DIPLGDGSPT-IARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSY---M 116

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQ 376
              + +L ++    S  G +T  A NP G    S  + V  P    +       I  T+ 
Sbjct: 117 APGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRIS---RPTIGSTKS 173

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDY 436
            +    + IS          V  D    EG     +C  TG P PEV W  +  ++   Y
Sbjct: 174 TDNMNPVSIS----------VGSDVTAIEGVTVSIECNATGVPRPEVFWSKDGLRL---Y 220

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
             +  V E  N  L+ITN  + DSG  TC A++  G+ +    + ++  +Q
Sbjct: 221 PGEYPVLE--NKTLIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDKQ 269



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 144/607 (23%), Positives = 222/607 (36%), Gaps = 93/607 (15%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I W K+G  L       +    G  +L I  +     G++TC ATN +GE   +++
Sbjct: 96   PKPSIIWRKDGRELIGAGSYMAP---GNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSN 152

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            I++ D   +L     P     IG+                   V IS  +++   EG  +
Sbjct: 153  IRVVDP--VLPRISRPT----IGS----------TKSTDNMNPVSISVGSDVTAIEGVTV 196

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851
              ECN   +  P  ++ W  +   L  G  Y    + + +   IT+   +DSG YTC A 
Sbjct: 197  SIECNA--TGVPRPEVFWSKDGLRLYPG-EYPVLENKTLI---ITNAKVDDSGYYTCTAQ 250

Query: 2852 NSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEARLAKGRRPSVPDTEYPKP 2911
            +S G  + S  +    DK     ++   G   L+    A E  + +     V  ++    
Sbjct: 251  SSIGKDSQSSVVEILRDKQ----SRLVFGVMSLKYSFSAAEVPIIQRTTDKVEKSDMKPV 306

Query: 2912 EWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLE-QGSRFKLTSDFGFVT 2970
            +  + I  +   + G  + L         PD  IEW   GK++  QG R           
Sbjct: 307  D--VRIGGQVTSLSGVDITLNCSARGLPPPD--IEWMNGGKMITVQGPR----------- 351

Query: 2971 LDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLED 3030
            L L +V   DSG YTC A N  G A  S+ V  T  D ++                   D
Sbjct: 352  LVLRNVMSSDSGNYTCIASNVVGRASASTMVNVT--DPIMPSIARATS-----------D 398

Query: 3031 SLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKT 3090
             +  +P +  + D G+     T            + H  A    TG    V+ W    + 
Sbjct: 399  HIATQP-ESANQDIGKSIVLLT--------GSSLVLHCNA----TGHPQPVVTWRRGSQP 445

Query: 3091 IE--ASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK 3148
            I   A H +      G   L IL  +  D   Y+C A+N  G+A  S +L     SK   
Sbjct: 446  ISGLADHTL-----IG-TSLRILNLEPADMEEYTCTASNVGGKAAASTELTVKALSKPNI 499

Query: 3149 PRFTTHIQNIE---------GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIK 3199
                T I N+           L   Q++    T      P   I W+ +G+P+    + +
Sbjct: 500  KTVRTRINNVRRDVTVPIGTTLTTIQNSTVVITCPTEGFPKPIISWFKDGEPITPDLKYE 559

Query: 3200 TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAK 3259
              +    ++ DI   Q  D G Y C A N  G D    +I    K  V +       +  
Sbjct: 560  -ANCTSLIIRDI---QPGDEGSYTCTAVNPMGTDVNNMSIT-VTKPPVIINVKGSFEVTD 614

Query: 3260 IRELESL 3266
            IREL S+
Sbjct: 615  IRELLSI 621



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 52/221 (23%), Positives = 97/221 (43%), Gaps = 15/221 (6%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
            P++ +    + +  G+  + +    G+P+P VTW+     ++ S +   +T     TL +
Sbjct: 1158 PRVDKLDSLATVVRGSTLRIRCAAYGSPKPSVTWY-----VVGSERKADLTVLPDGTLEL 1212

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE- 384
             N    D G+YT +A N  G    S  + V  P  S + +  +  I     +   +R   
Sbjct: 1213 ENVDFMDEGNYTCVARNAYGVTSRSTNVTVLVPP-SILDNFFADAILVQHSKLLHKRYSS 1271

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
            I+  ++  Q ++      V  G      C V+GRP P + W  N  +I +D + +++V  
Sbjct: 1272 ITRLSIRRQQIRQAA---VERGANLIIGCPVSGRPLPAIQWLRNGLKISND-SRQVIV-- 1325

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
                 +MI ++ L  +G   C  +N +GE      L+V E+
Sbjct: 1326 --GGVIMIRDIQLQHAGEYFCYVKNTAGEDGGGVDLSVRER 1364



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 145/656 (22%), Positives = 255/656 (38%), Gaps = 118/656 (17%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P  +    I +I D   ++ G     +     V  P   + W  +G++L     Y    +
Sbjct: 63   PLGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPS--IIWRKDGRELIGAGSYMAPGN 120

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEK 3396
              ++I  +   +    G + C ATN +G DS  +N++       ++D  LPR        
Sbjct: 121  GSLLIQQVAASHH---GVFTCTATNPVGEDSVSSNIR-------VVDPVLPR-------- 162

Query: 3397 LQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456
                   + R    S +      PV     S++  + EG     E   T    P  +V W
Sbjct: 163  -------ISRPTIGSTKSTDNMNPVSISVGSDVTAI-EGVTVSIECNATGVPRP--EVFW 212

Query: 3457 YWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV-QGK 3515
              +G  L  G     +       L I+    +DSG Y C A ++ G+   ++ +++ + K
Sbjct: 213  SKDGLRLYPGE----YPVLENKTLIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDK 268

Query: 3516 RNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSA 3575
            ++ ++   +      +  ++  ++  +  V+    +          T+ S + ++ N SA
Sbjct: 269  QSRLVFGVMSLKYSFSAAEVPIIQRTTDKVEKSDMKPVDVRIGGQVTSLSGVDITLNCSA 328

Query: 3576 HFECRLIPVNDSSMRVEWFHNGKPL-LTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKA 3634
                R +P  D    +EW + GK + + G R           L +  V   D+G YTC A
Sbjct: 329  ----RGLPPPD----IEWMNGGKMITVQGPR-----------LVLRNVMSSDSGNYTCIA 369

Query: 3635 TNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNP 3694
            +N  G A+ S  + V        +P +PS  ++ ++ I    E+ ++             
Sbjct: 370  SNVVGRASASTMVNVT-------DPIMPSIARATSDHIATQPESANQ------------- 409

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
                 +I  +I +  G  +   C     G P   + W    +P + G   HTL       
Sbjct: 410  -----DIGKSIVLLTGSSLVLHCNA--TGHPQPVVTWRRGSQPIS-GLADHTLIGTSLRI 461

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L+++     D  EYTC A+N  G A  + ++T  A             +S   IK + R 
Sbjct: 462  LNLE---PADMEEYTCTASNVGGKAAASTELTVKA-------------LSKPNIKTV-RT 504

Query: 3815 RISDAPKEE--PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
            RI++  ++   PI +T    +T I++ TV         C  E    PK  I W+++G+ +
Sbjct: 505  RINNVRRDVTVPIGTT----LTTIQNSTVV------ITCPTEGF--PKPIISWFKDGEPI 552

Query: 3873 PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
                +Y    +    SL I  +   D G Y C AVN  G D    +I+  K P II
Sbjct: 553  TPDLKY----EANCTSLIIRDIQPGDEGSYTCTAVNPMGTDVNNMSITVTKPPVII 604



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 104/435 (23%), Positives = 174/435 (40%), Gaps = 72/435 (16%)

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEK-TRHIEESK 1161
            L I + + +DSG YT  A+++ G+   S S  VE      +  +   +  K +    E  
Sbjct: 232  LIITNAKVDDSGYYTCTAQSSIGKD--SQSSVVEILRDKQSRLVFGVMSLKYSFSAAEVP 289

Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221
             ++      E S  KPV V+       +S G +I L C     G P   +EW + G+ +T
Sbjct: 290  IIQRTTDKVEKSDMKPVDVRIGGQVTSLS-GVDITLNCSAR--GLPPPDIEWMNGGKMIT 346

Query: 1222 V-GSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280
            V G R           L + +  S+D+G YT  A N +G A  S +V V   +D +  + 
Sbjct: 347  VQGPR-----------LVLRNVMSSDSGNYTCIASNVVGRASASTMVNV---TDPIMPSI 392

Query: 1281 NEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQ 1340
                 + I      A + +   +DI             +I  + G+++ L C     G  
Sbjct: 393  ARATSDHI------ATQPESANQDIG-----------KSIVLLTGSSLVLHCNA--TGHP 433

Query: 1341 TMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCAL 1400
               V W    +PI         +     +L +L++ P D   YTC A+N  G+A  S   
Sbjct: 434  QPVVTWRRGSQPISG----LADHTLIGTSLRILNLEPADMEEYTCTASNVGGKAAAST-- 487

Query: 1401 RVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQ 1460
                  +L +++     ++ ++   +  R   T  I  ++T               I+  
Sbjct: 488  ------ELTVKALSKPNIKTVRTRINNVRRDVTVPIGTTLT--------------TIQNS 527

Query: 1461 HVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCR 1520
             V   C  E        + WFK+G+P+T   ++    +    +L I D+   D G YTC 
Sbjct: 528  TVVITCPTEGFPKPI--ISWFKDGEPITPDLKY----EANCTSLIIRDIQPGDEGSYTCT 581

Query: 1521 AVNLVGTDEVSCRLT 1535
            AVN +GTD  +  +T
Sbjct: 582  AVNPMGTDVNNMSIT 596



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 162/689 (23%), Positives = 251/689 (36%), Gaps = 127/689 (18%)

Query: 3114 KTTDSGTYSCRATNKWGQAEISVKLECVDKSKG--QKPRFTTHIQNIEG----------- 3160
            +  DSG Y+C A N  G+  IS +++ ++ SK   ++P     I   +G           
Sbjct: 19   RPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAPRDIPLGDGSPTIARIADNA 78

Query: 3161 -LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDS 3219
             +  G     +C    V  P   I W  +G+ +  +       +   ++  +A + +   
Sbjct: 79   TVLTGSRLTIDCVATGVPKPS--IIWRKDGRELIGAGSYMAPGNGSLLIQQVAASHH--- 133

Query: 3220 GEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSA 3279
            G + C A N  GED   + I         ++ + P      R      G+   T ST + 
Sbjct: 134  GVFTCTATNPVGEDSVSSNIRV-------VDPVLP------RISRPTIGS---TKSTDNM 177

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
             P   I+   DVT  +EG +   E     V  P+  V W  +G +L  G  Y    +  +
Sbjct: 178  NPVS-ISVGSDVTA-IEGVTVSIECNATGVPRPE--VFWSKDGLRLYPGE-YPVLENKTL 232

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQT 3399
            +I +      ++SG Y C A + +G+DS  + ++    +     S+L  G+         
Sbjct: 233  IITNAKV---DDSGYYTCTAQSSIGKDSQSSVVEILRDK----QSRLVFGVMSLKYSFSA 285

Query: 3400 LEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGE-NAHFEARLTPTDDPNLKVEWYW 3458
             E  +++R    VE+   K PV       + +L   +   +  AR  P  D    +EW  
Sbjct: 286  AEVPIIQRTTDKVEKSDMK-PVDVRIGGQVTSLSGVDITLNCSARGLPPPD----IEWMN 340

Query: 3459 NGKSLKA-GSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRN 3517
             GK +   G R           L +      DSG Y C A N  G A  +AS  V     
Sbjct: 341  GGKMITVQGPR-----------LVLRNVMSSDSGNYTCIASNVVGRA--SASTMVN---- 383

Query: 3518 IILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHF 3577
             + +  +P     T D IA  +  S   D                T S L+L  N++ H 
Sbjct: 384  -VTDPIMPSIARATSDHIAT-QPESANQDI--------GKSIVLLTGSSLVLHCNATGHP 433

Query: 3578 ECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNR 3637
            +    PV      V W    +P ++G    T+      IL +      D   YTC A+N 
Sbjct: 434  Q----PV------VTWRRGSQP-ISGLADHTLIGTSLRILNL---EPADMEEYTCTASNV 479

Query: 3638 HGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRF 3697
             G+A  S +L VK     + +P +               +T+  R      D        
Sbjct: 480  GGKAAASTELTVKA----LSKPNI---------------KTVRTRINNVRRD-------V 513

Query: 3698 TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDI 3757
            TV I   +   +   V   C  E  G P   I WF +G P  T    +  N    I  DI
Sbjct: 514  TVPIGTTLTTIQNSTVVITCPTE--GFPKPIISWFKDGEPI-TPDLKYEANCTSLIIRDI 570

Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKIT 3786
                  D G YTC A N  G+      IT
Sbjct: 571  Q---PGDEGSYTCTAVNPMGTDVNNMSIT 596



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 133/578 (23%), Positives = 212/578 (36%), Gaps = 95/578 (16%)

Query: 1648 GTYTCRAINALGE-AVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEV 1706
            G +TC A N +GE +V+S I +V            +  LPR+++    S     +     
Sbjct: 134  GVFTCTATNPVGEDSVSSNIRVV------------DPVLPRISRPTIGSTKSTDNMN--- 178

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
                PV      D+   E      E      G P+  V W ++G+ +        + +  
Sbjct: 179  ----PVSISVGSDVTAIEGVTVSIECNA--TGVPRPEVFWSKDGLRLYPGE-YPVLENKT 231

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLED 1826
             +  N K    +DSG YTC A + +G+   SS + +      +L     S        E 
Sbjct: 232  LIITNAKV---DDSGYYTCTAQSSIGKDSQSSVVEILRDKQSRLVFGVMSLKYSFSAAEV 288

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
                +  + VE + +  P  + ++ G      G      C     P P+  +EW   GK+
Sbjct: 289  PIIQRTTDKVEKS-DMKPVDV-RIGGQVTSLSGVDITLNCSARGLPPPD--IEWMNGGKM 344

Query: 1887 LQ-SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
            +   G R           L +  V   DSG YTC A N +G+A +S  +NV      I  
Sbjct: 345  ITVQGPR-----------LVLRNVMSSDSGNYTCIASNVVGRASASTMVNVTDP---IMP 390

Query: 1946 SQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVN 2005
            S   +  + I           A Q +S        GK I    +  G  + L    T   
Sbjct: 391  SIARATSDHI-----------ATQPES---ANQDIGKSI---VLLTGSSLVLHCNAT--G 431

Query: 2006 DPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
             P   V W    +P+  G    T       +L IL     D   Y C A+N  G+A  ++
Sbjct: 432  HPQPVVTWRRGSQPI-SGLADHTLIG---TSLRILNLEPADMEEYTCTASNVGGKAAAST 487

Query: 2066 SVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGD 2125
             + V A S   + T+   R+  ++     +   PI            T LT+++N     
Sbjct: 488  ELTVKALSKPNIKTV-RTRINNVRR----DVTVPIG-----------TTLTTIQN----S 527

Query: 2126 RAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCK 2185
                 C  E    P   I WF +G+ I    +Y    +    +L I      D G+Y C 
Sbjct: 528  TVVITCPTEGFPKP--IISWFKDGEPITPDLKY----EANCTSLIIRDIQPGDEGSYTCT 581

Query: 2186 ATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQL 2223
            A N +G  VN  ++ V     +I++ +    +  IR+L
Sbjct: 582  AVNPMGTDVNNMSITVT-KPPVIINVKGSFEVTDIREL 618



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 117/461 (25%), Positives = 179/461 (38%), Gaps = 86/461 (18%)

Query: 3613 GFVILEIGGVYQR-----DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKS 3667
            G+VI + G +  R     D+G YTC A N  G+  +S   QVK     ++EP  P+    
Sbjct: 4    GYVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISS--QVK-----VIEPSKPT---- 52

Query: 3668 GTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTM 3727
                   +E  +  R +I + D  P   R    I DN  V  G  +  DC     G P  
Sbjct: 53   -------IERPVAPR-DIPLGDGSPTIAR----IADNATVLTGSRLTIDC--VATGVPKP 98

Query: 3728 RIDWFHNGRP-FATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
             I W  +GR     GS +   N     +L I  + A   G +TC ATN  G  + ++ I 
Sbjct: 99   SIIWRKDGRELIGAGSYMAPGNG----SLLIQQVAASHHGVFTCTATNPVGEDSVSSNIR 154

Query: 3787 CSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846
                   V++  LP      +I     G         P+  +    +T I+  TV     
Sbjct: 155  -------VVDPVLP------RISRPTIGSTKSTDNMNPVSISVGSDVTAIEGVTVS---- 197

Query: 3847 VRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRA 3906
               EC       P+  + W ++G  L  G  Y  + +    +L I     +DSG Y C A
Sbjct: 198  --IECNATGV--PRPEVFWSKDGLRLYPG-EYPVLENK---TLIITNAKVDDSGYYTCTA 249

Query: 3907 VNDFGEDFTKATISCKKLPDIILQNQVPRG-MKRSEALTQMEATIKKYTSEVYLTEDDLY 3965
             +  G+D   + +    L D   Q+++  G M    + +  E  I + T++  + + D+ 
Sbjct: 250  QSSIGKDSQSSVVEI--LRD--KQSRLVFGVMSLKYSFSAAEVPIIQRTTD-KVEKSDMK 304

Query: 3966 DVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPI 4025
             VD     R   Q+   TSL  ++ T   C     G P   +EW   GK +        +
Sbjct: 305  PVD----VRIGGQV---TSLSGVDIT-LNCSAR--GLPPPDIEWMNGGKMI-------TV 347

Query: 4026 YDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTT 4066
                 V  N   V   DSG Y C A+N+ G      ++  T
Sbjct: 348  QGPRLVLRN---VMSSDSGNYTCIASNVVGRASASTMVNVT 385



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 45/151 (29%), Positives = 70/151 (46%), Gaps = 20/151 (13%)

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEG 4735
            D  TL +  A P D G Y C A NS G+  +++++KV +P +      + P RDI + +G
Sbjct: 9    DNGTLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAP-RDIPLGDG 67

Query: 4736 QP-----AQFKTQIT-SKI----------KPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
             P     A   T +T S++          KP+I W ++G  +     +  +  GN + LL
Sbjct: 68   SPTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSY--MAPGNGS-LL 124

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            I        G FTC AT   G+   S+ + V
Sbjct: 125  IQQVAASHHGVFTCTATNPVGEDSVSSNIRV 155



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 107/473 (22%), Positives = 179/473 (37%), Gaps = 71/473 (15%)

Query: 1099 GYVALD-----IASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEK 1153
            GYV  D     +   R  DSG YT  A N+ G+  +S+ + V   S     +I R +   
Sbjct: 4    GYVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSK---PTIERPV--A 58

Query: 1154 TRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEW 1213
             R I              +    P   +   N   V  G  + ++C     G P   + W
Sbjct: 59   PRDIP-------------LGDGSPTIARIADNAT-VLTGSRLTIDC--VATGVPKPSIIW 102

Query: 1214 FHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERS 1273
              +GR + +G+   +Y   G  +L I    ++  G +T  A N +G    S+ +RV+   
Sbjct: 103  RKDGREL-IGAG--SYMAPGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVV--- 156

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECR 1333
            D V    +   I   +  ++    +  V  D+T                +EG  V +EC 
Sbjct: 157  DPVLPRISRPTIGSTKSTDNMNPVSISVGSDVTA---------------IEGVTVSIECN 201

Query: 1334 LQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE 1393
                G     V W  +G  +  G    P  E   + +    V  +DSG YTC A + +G+
Sbjct: 202  A--TGVPRPEVFWSKDGLRLYPGEY--PVLENKTLIITNAKV--DDSGYYTCTAQSSIGK 255

Query: 1394 AVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSI 1453
               S  + ++  K   L     S        E     + TD +++S  +KP  V     +
Sbjct: 256  DSQSSVVEILRDKQSRLVFGVMSLKYSFSAAEVPIIQRTTDKVEKS-DMKPVDVRIGGQV 314

Query: 1454 ENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTI-GHRFRPIHDFGYVALDIIDLIAE 1512
             + + G  +   C    +   +  +EW   G+ +T+ G R           L + ++++ 
Sbjct: 315  TS-LSGVDITLNCSARGLPPPD--IEWMNGGKMITVQGPR-----------LVLRNVMSS 360

Query: 1513 DSGIYTCRAVNLVGTDEVS--CRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSK 1563
            DSG YTC A N+VG    S    +T      I R+T +    +     +D  K
Sbjct: 361  DSGNYTCIASNVVGRASASTMVNVTDPIMPSIARATSDHIATQPESANQDIGK 413



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 52/210 (24%), Positives = 80/210 (38%), Gaps = 35/210 (16%)

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            + K   P+  K+     V  G   R  C   G P P VTW++   + + D    + V   
Sbjct: 1152 ANKFTRPRVDKLDSLATVVRGSTLRIRCAAYGSPKPSVTWYVVGSERKAD----LTVLPD 1207

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE---------- 495
            G   L + NV   D G  TCVARN  G T+    + V+    ++   F +          
Sbjct: 1208 G--TLELENVDFMDEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKLL 1265

Query: 496  --RFSTLN-------------VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIH 540
              R+S++              V  G  +++     G P P I W ++G+  I N   ++ 
Sbjct: 1266 HKRYSSITRLSIRRQQIRQAAVERGANLIIGCPVSGRPLPAIQWLRNGLK-ISNDSRQVI 1324

Query: 541  TDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              G     DI    A +   Y C  +N AG
Sbjct: 1325 VGGVIMIRDIQLQHAGE---YFCYVKNTAG 1351



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 6/65 (9%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P++SW +   P+    KY      +    SL+I+ I PGDEG YTCTA N  G  +
Sbjct: 537 GFPKPIISWFKDGEPITPDLKY------EANCTSLIIRDIQPGDEGSYTCTAVNPMGTDV 590

Query: 157 CSVYI 161
            ++ I
Sbjct: 591 NNMSI 595



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 18/147 (12%)

Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK-----EQVVAPK--------- 492
           N  L++     +DSG  TC A N  G+     ++ VIE      E+ VAP+         
Sbjct: 10  NGTLVLRRARPADSGRYTCTANNSRGKDHISSQVKVIEPSKPTIERPVAPRDIPLGDGSP 69

Query: 493 FVERFS-TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIP 551
            + R +    V  G  + ++  A G P P I W+KDG  +I       +   G  +L I 
Sbjct: 70  TIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGS---YMAPGNGSLLIQ 126

Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578
           +  AS    + CTA N  G  +  + +
Sbjct: 127 QVAASHHGVFTCTATNPVGEDSVSSNI 153



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 49/188 (26%), Positives = 70/188 (37%), Gaps = 28/188 (14%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            PR V ++ S  ++V   T +  C  A  G P   V W+  G     K   T + D     
Sbjct: 1158 PR-VDKLDSLATVVRGSTLRIRC--AAYGSPKPSVTWYVVGSE--RKADLTVLPDGTLEL 1212

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV----YDSQLPKHMKSIEKIR 4088
             N  ++   D G Y C A N YG+      +     P I+     D+ L +H K + K  
Sbjct: 1213 ENVDFM---DEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKLLHKRY 1269

Query: 4089 EMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNG 4148
                   +  +Q+ +                  VE G      C V+G P P + WL NG
Sbjct: 1270 SSITRLSIRRQQIRQ----------------AAVERGANLIIGCPVSGRPLPAIQWLRNG 1313

Query: 4149 NTIVNGSR 4156
              I N SR
Sbjct: 1314 LKISNDSR 1321



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 6/88 (6%)

Query: 67  GEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQT 126
           G+ SP I  +I  NA    G     +    G P P + W +    L+    Y        
Sbjct: 65  GDGSPTI-ARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMA-----P 118

Query: 127 GDVSLLIKQIGPGDEGEYTCTARNQYGE 154
           G+ SLLI+Q+     G +TCTA N  GE
Sbjct: 119 GNGSLLIQQVAASHHGVFTCTATNPVGE 146



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P   + W+KDG PIT   +    +     SL I  ++  D GSYT  AVN +G  ++  S
Sbjct: 539 PKPIISWFKDGEPITPDLK----YEANCTSLIIRDIQPGDEGSYTCTAVNPMGTDVNNMS 594

Query: 860 IRV 862
           I V
Sbjct: 595 ITV 597



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 45/170 (26%), Positives = 74/170 (43%), Gaps = 15/170 (8%)

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASR 1028
            L +++V   D G+YTC A NA G  + S N+T++    I+        L +   L    R
Sbjct: 1210 LELENVDFMDEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKLLH-KR 1268

Query: 1029 YSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITS 1088
            YS  T   ++  Q+ R     +G N I+         R  P       ++W  NG +I++
Sbjct: 1269 YSSITRLSIR-RQQIRQAAVERGANLII---GCPVSGRPLP------AIQWLRNGLKISN 1318

Query: 1089 ANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
             +R Q     G V + I  ++ + +G Y    +N AGE      ++V  R
Sbjct: 1319 DSR-QVI--VGGVIM-IRDIQLQHAGEYFCYVKNTAGEDGGGVDLSVRER 1364



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 75  EQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIK 134
           + I K+     G +        G+P PVV+W R   P+     +++         SL I 
Sbjct: 409 QDIGKSIVLLTGSSLVLHCNATGHPQPVVTWRRGSQPISGLADHTLI------GTSLRIL 462

Query: 135 QIGPGDEGEYTCTARNQYGEAICS 158
            + P D  EYTCTA N  G+A  S
Sbjct: 463 NLEPADMEEYTCTASNVGGKAAAS 486



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 37/162 (22%), Positives = 62/162 (38%), Gaps = 29/162 (17%)

Query: 3983 TSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPED 4042
            T+L  ++ +         G P   + WF +G+P+    +    Y+    ++    + P D
Sbjct: 519  TTLTTIQNSTVVITCPTEGFPKPIISWFKDGEPITPDLK----YEANCTSLIIRDIQPGD 574

Query: 4043 SGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVV 4102
             G Y C A N  G D     I  T  P I+                 ++ S++VT    +
Sbjct: 575  EGSYTCTAVNPMGTDVNNMSITVTKPPVII----------------NVKGSFEVTD---I 615

Query: 4103 EESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
             E  +      V++P  VT+         C VTG P+P + W
Sbjct: 616  RELLSITTGAIVTIPRGVTI------TIRCEVTGKPEPNITW 651



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 48/205 (23%), Positives = 77/205 (37%), Gaps = 34/205 (16%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V  G  +   C   G P P+V WY    ++   +   ++   D  TL +      DEG+Y
Sbjct: 1169 VVRGSTLRIRCAAYGSPKPSVTWY----VVGSERKADLTVLPDG-TLELENVDFMDEGNY 1223

Query: 4694 KCVAYNSAGRVTVAAKLKV-TQPDQADNL-----------------PALTPL-------R 4728
             CVA N+ G  + +  + V   P   DN                   ++T L       R
Sbjct: 1224 TCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKLLHKRYSSITRLSIRRQQIR 1283

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
               V  G        ++ +  P IQWLR G  I  + D + +  G   V++I +   +  
Sbjct: 1284 QAAVERGANLIIGCPVSGRPLPAIQWLRNGLKI--SNDSRQVIVG--GVIMIRDIQLQHA 1339

Query: 4789 GTFTCRATTAAGQVETSAKLVVKSK 4813
            G + C     AG+      L V+ +
Sbjct: 1340 GEYFCYVKNTAGEDGGGVDLSVRER 1364



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 5/66 (7%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KDG P+    +    +     +L I+ +   D G YTC A N +G    + ++T V
Sbjct: 543  ISWFKDGEPITPDLK----YEANCTSLIIRDIQPGDEGSYTCTAVNPMGTDVNNMSIT-V 597

Query: 1003 TKKDII 1008
            TK  +I
Sbjct: 598  TKPPVI 603



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 42/159 (26%), Positives = 68/159 (42%), Gaps = 15/159 (9%)

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L+++ +   D G YTC A N +G  + +  +T      I L++     +  +  K L + 
Sbjct: 1210 LELENVDFMDEGNYTCVARNAYGVTSRSTNVTVLVPPSI-LDNFFADAILVQHSKLLHK- 1267

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
            R S   +    +S   +   QI+   VE    +   C V  +  P   I+W RNG  + +
Sbjct: 1268 RYSSITR----LSIRRQ---QIRQAAVERGANLIIGCPVSGR--PLPAIQWLRNGLKISN 1318

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
              R   V   G V + I  +  + +GEY C   N  GED
Sbjct: 1319 DSRQVIV---GGVIM-IRDIQLQHAGEYFCYVKNTAGED 1353



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 44/172 (25%), Positives = 71/172 (41%), Gaps = 19/172 (11%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P P+I W+++  PI  +PD +     T   LIIR +   D   +   A N  GT   
Sbjct: 536  EGFPKPIISWFKDGEPI--TPDLKYEANCTS--LIIRDIQPGDEGSYTCTAVNPMGTDVN 591

Query: 4495 SANLVVEEK----RRQGRGGIVPPSFTL---TAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
            + ++ V +       +G   +      L   T   V +  G  + +  +VTG    ++ W
Sbjct: 592  NMSITVTKPPVIINVKGSFEVTDIRELLSITTGAIVTIPRGVTITIRCEVTGKPEPNITW 651

Query: 4548 --LKNGKK----VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
              +  G +    + P  R   L  D   +L I      D+ +Y CVA N AG
Sbjct: 652  YRIPEGSQRWQLITPLDRYMHLRSD--MSLAIDRTAQVDAAQYVCVATNIAG 701



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 13/124 (10%)

Query: 1103 LDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKF 1162
            L++ +V   D G YT VARNA G    S ++TV     +   SI    +     ++ SK 
Sbjct: 1210 LELENVDFMDEGNYTCVARNAYGVTSRSTNVTV-----LVPPSILDNFFADAILVQHSKL 1264

Query: 1163 VEPMY-QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221
            +   Y  I  +S  +    Q       V  G N+ + C +   G P   ++W  NG  ++
Sbjct: 1265 LHKRYSSITRLSIRRQQIRQ-----AAVERGANLIIGCPVS--GRPLPAIQWLRNGLKIS 1317

Query: 1222 VGSR 1225
              SR
Sbjct: 1318 NDSR 1321



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 47/217 (21%), Positives = 84/217 (38%), Gaps = 20/217 (9%)

Query: 646 VTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQD 705
           VTA+EG  +  E      G P  ++ W K+G  +          +    +L + +  + D
Sbjct: 188 VTAIEGVTVSIECNA--TGVPRPEVFWSKDGLRLYPGEYPVLENK----TLIITNAKVDD 241

Query: 706 SGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQ 765
           SG YTC A S+ G     +V+ +  R    R      +L+Y     +    Q      E+
Sbjct: 242 SGYYTCTAQSSIGKDSQSSVVEIL-RDKQSRLVFGVMSLKYSFSAAEVPIIQRTTDKVEK 300

Query: 766 TSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNF 825
           +  +P  +R     G++            +    P   +EW   G+ IT           
Sbjct: 301 SDMKPVDVR---IGGQVTSLSGVDITLNCSARGLPPPDIEWMNGGKMITVQG-------- 349

Query: 826 GYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
               L + ++ + D+G+YT  A N +G A ++  + V
Sbjct: 350 --PRLVLRNVMSSDSGNYTCIASNVVGRASASTMVNV 384



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 44/182 (24%), Positives = 68/182 (37%), Gaps = 12/182 (6%)

Query: 3979 IQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWV 4038
            + S  + +E  T   EC     G P  +V W  +G  L +   +  + +   +  N    
Sbjct: 184  VGSDVTAIEGVTVSIECNAT--GVPRPEVFWSKDGLRL-YPGEYPVLENKTLIITN---A 237

Query: 4039 YPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTP 4098
              +DSG Y C A +  G D   +V++          S+L   + S+ K     A   +  
Sbjct: 238  KVDDSGYYTCTAQSSIGKDSQSSVVEILRDK----QSRLVFGVMSL-KYSFSAAEVPIIQ 292

Query: 4099 EQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI-VNGSRY 4157
                +  K+   PV V +   VT   G      C   G P P + W+  G  I V G R 
Sbjct: 293  RTTDKVEKSDMKPVDVRIGGQVTSLSGVDITLNCSARGLPPPDIEWMNGGKMITVQGPRL 352

Query: 4158 KL 4159
             L
Sbjct: 353  VL 354



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 46/212 (21%), Positives = 77/212 (36%), Gaps = 25/212 (11%)

Query: 4506 QGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEE 4565
            QG      P          V  G  +R+     G+    V W   G + + D+    +  
Sbjct: 1150 QGANKFTRPRVDKLDSLATVVRGSTLRIRCAAYGSPKPSVTWYVVGSERKADLT---VLP 1206

Query: 4566 DGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT-----------KDKPKP 4614
            DGT  L  ++    D G Y CVA N+ G         V +P +               K 
Sbjct: 1207 DGTLELENVDF--MDEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKL 1264

Query: 4615 QTKAANAPPEII---EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQ 4670
              K  ++   +    + ++   V  G  +   C + G+PLP +QW + G K+   S+   
Sbjct: 1265 LHKRYSSITRLSIRRQQIRQAAVERGANLIIGCPVSGRPLPAIQWLRNGLKISNDSRQVI 1324

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
            +        + I +   +  G+Y C   N+AG
Sbjct: 1325 VGG-----VIMIRDIQLQHAGEYFCYVKNTAG 1351



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 22/124 (17%)

Query: 4040 PEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPE 4099
            P DSG Y C A N  G D   + +K       V +   P    +IE+         V P 
Sbjct: 20   PADSGRYTCTANNSRGKDHISSQVK-------VIEPSKP----TIER--------PVAPR 60

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
             +     +   P    + D  TV  G      C  TG PKP ++W  +G  ++    Y  
Sbjct: 61   DIPLGDGS---PTIARIADNATVLTGSRLTIDCVATGVPKPSIIWRKDGRELIGAGSYMA 117

Query: 4160 TYDG 4163
              +G
Sbjct: 118  PGNG 121



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 38/131 (29%), Positives = 56/131 (42%), Gaps = 8/131 (6%)

Query: 2243 RFVTELRGTT-HVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVS 2301
            R VT   GTT    +  T    C  E    P   I ++ +G+ +       + ++    S
Sbjct: 511  RDVTVPIGTTLTTIQNSTVVITCPTEGFPKPI--ISWFKDGEPITP----DLKYEANCTS 564

Query: 2302 LDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEP 2361
            L I+   P D G Y+  A+N +G   + +S+TVT    II+     E +  IREL S   
Sbjct: 565  LIIRDIQPGDEGSYTCTAVNPMGTDVNNMSITVTKPPVIINVKGSFE-VTDIRELLSITT 623

Query: 2362 FKRPEIPEPVT 2372
                 IP  VT
Sbjct: 624  GAIVTIPRGVT 634



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 64/290 (22%), Positives = 112/290 (38%), Gaps = 48/290 (16%)

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDS 1972
            DSG YTC A N+ G+       ++ S+  +I  S+    +E+            A +D  
Sbjct: 22   DSGRYTCTANNSRGKD------HISSQVKVIEPSK--PTIER----------PVAPRDIP 63

Query: 1973 FVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDF 2032
                 P   +   NA V  G  + ++   T V  P+  + W  +GR +     +      
Sbjct: 64   LGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPS--IIWRKDGRELIGAGSYMAP--- 118

Query: 2033 GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELE 2092
            G  +L I    A   G + C ATN VGE   +S+++V       +D +          L 
Sbjct: 119  GNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRV-------VDPV----------LP 161

Query: 2093 KYERPK-PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
            +  RP     +      PV ++  + +  + EG     EC    +  P   + W  +G +
Sbjct: 162  RISRPTIGSTKSTDNMNPVSISVGSDVTAI-EGVTVSIECNATGV--PRPEVFWSKDGLR 218

Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            +  G  Y    +     L I     +DSG Y C A + +G+   +  +++
Sbjct: 219  LYPG-EYPVLEN---KTLIITNAKVDDSGYYTCTAQSSIGKDSQSSVVEI 264



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            W KDGR +  +    ++   G  +L I+ V     G +TC A N +G+ + S+N+ +V
Sbjct: 102  WRKDGRELIGAG---SYMAPGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVV 156



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 4/54 (7%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            + W+ + +P+    ++ E N    +  DI    P D G+YTC A+N +G  V +
Sbjct: 543  ISWFKDGEPITPDLKY-EANCTSLIIRDIQ---PGDEGSYTCTAVNPMGTDVNN 592



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 49/202 (24%), Positives = 81/202 (40%), Gaps = 16/202 (7%)

Query: 1646 DSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDE 1705
            D G YTC A NA G    S    V    SI      +  L + ++L     ++R+S+   
Sbjct: 1219 DEGNYTCVARNAYGVTSRSTNVTVLVPPSILDNFFADAILVQHSKL----LHKRYSS--- 1271

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
             IT+  +    ++  + A  + A+        G P   ++WLRNG+ I   +R   +   
Sbjct: 1272 -ITRLSIRRQQIR--QAAVERGANLIIGCPVSGRPLPAIQWLRNGLKISNDSRQVIV--- 1325

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQ--LESQHESALQKIQQ 1823
            G V + ++ +  + +G Y C   N  GE      L V+ +   Q  +    E    +  Q
Sbjct: 1326 GGVIM-IRDIQLQHAGEYFCYVKNTAGEDGGGVDLSVRERIVGQWYISPWTEYLATRFVQ 1384

Query: 1824 LEDSSRYQRREDVEVAVNQAPR 1845
            L+      R + VE      PR
Sbjct: 1385 LKSGFTQIRAQTVEPGFYDVPR 1406



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 5/83 (6%)

Query: 491  PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
            P+  +  S   V  G  + +   A G+P P +TW   G       +L +  DG   TL++
Sbjct: 1158 PRVDKLDSLATVVRGSTLRIRCAAYGSPKPSVTWYVVGSE--RKADLTVLPDG---TLEL 1212

Query: 551  PRAKASDAAWYQCTAQNVAGSTA 573
                  D   Y C A+N  G T+
Sbjct: 1213 ENVDFMDEGNYTCVARNAYGVTS 1235



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 47/163 (28%), Positives = 66/163 (40%), Gaps = 23/163 (14%)

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            LE+  V   D G YTC A N +G  + S  + V      ++ P +  +F +    +Q   
Sbjct: 1210 LELENVDFMDEGNYTCVARNAYGVTSRSTNVTV------LVPPSILDNFFADAILVQH-S 1262

Query: 3677 ETLHKR-EEIT-IEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHN 3734
            + LHKR   IT +   +    +  VE   N+ +  G PV         G P   I W  N
Sbjct: 1263 KLLHKRYSSITRLSIRRQQIRQAAVERGANLII--GCPVS--------GRPLPAIQWLRN 1312

Query: 3735 GRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG 3777
            G   +  SR   +   G I   I  I  + AGEY C   N  G
Sbjct: 1313 GLKISNDSRQVIVG--GVIM--IRDIQLQHAGEYFCYVKNTAG 1351



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 4/70 (5%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V  G  + +   V+G     + WL+NG K+  D R  I+       ++I +   Q +G+Y
Sbjct: 1287 VERGANLIIGCPVSGRPLPAIQWLRNGLKISNDSRQVIVGG----VIMIRDIQLQHAGEY 1342

Query: 4585 ECVAINSAGE 4594
             C   N+AGE
Sbjct: 1343 FCYVKNTAGE 1352



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 16/44 (36%), Positives = 21/44 (47%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154
            PV +S+   VT  EG      C  TG P+P V W  +G  +  G
Sbjct: 179  PVSISVGSDVTAIEGVTVSIECNATGVPRPEVFWSKDGLRLYPG 222



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 71/339 (20%), Positives = 126/339 (37%), Gaps = 31/339 (9%)

Query: 3580 RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDA-GLYTCKATNRH 3638
            R IP+ D S  +    +   +LTGSR+ TI+     + +   ++++D   L    +    
Sbjct: 60   RDIPLGDGSPTIARIADNATVLTGSRL-TIDCVATGVPKPSIIWRKDGRELIGAGSYMAP 118

Query: 3639 GEATVSCKLQVKGRQGII-LEPQLPSHFKSGTESIQKLEETLHKREEITIEDEK--PNPP 3695
            G  ++  +       G+       P    S + +I+ ++  L +    TI   K   N  
Sbjct: 119  GNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVVDPVLPRISRPTIGSTKSTDNMN 178

Query: 3696 RFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIAL 3755
              ++ +  ++   EG  V  +C     G P   + W  +G     G      N      L
Sbjct: 179  PVSISVGSDVTAIEGVTVSIECNA--TGVPRPEVFWSKDGLRLYPGEYPVLENK----TL 232

Query: 3756 DIDYIYARDAGEYTCRATNKWG--SATTTAKITCSAKRDIVL-ESQLPQGMSGEKIKELE 3812
             I      D+G YTC A +  G  S ++  +I    +  +V     L    S  ++  ++
Sbjct: 233  IITNAKVDDSGYYTCTAQSSIGKDSQSSVVEILRDKQSRLVFGVMSLKYSFSAAEVPIIQ 292

Query: 3813 RGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL 3872
              R +D  ++  +     +   Q+ S       GV        +  P   IEW   GK++
Sbjct: 293  --RTTDKVEKSDMKPVDVRIGGQVTS-----LSGVDITLNCSARGLPPPDIEWMNGGKMI 345

Query: 3873 PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                   TV     V  +++   + DSG Y C A N  G
Sbjct: 346  -------TVQGPRLVLRNVM---SSDSGNYTCIASNVVG 374



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 44/195 (22%), Positives = 73/195 (37%), Gaps = 20/195 (10%)

Query: 659  RIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718
            R    G P   + W   G   +A     ++   G + L+  +++  D G YTC A +A G
Sbjct: 1178 RCAAYGSPKPSVTWYVVGSERKAD---LTVLPDGTLELE--NVDFMDEGNYTCVARNAYG 1232

Query: 719  VAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQD 778
                     VT R+T       P  L       D    QH + + ++ S   +     Q 
Sbjct: 1233 ---------VTSRSTNVTVLVPPSILDNF--FADAILVQHSKLLHKRYSSITRLSIRRQQ 1281

Query: 779  LGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAE 838
            + +    R A+          P   ++W ++G  I+  SR   +   G V + I  ++ +
Sbjct: 1282 IRQAAVERGANLIIGCPVSGRPLPAIQWLRNGLKISNDSRQVIV---GGV-IMIRDIQLQ 1337

Query: 839  DAGSYTVRAVNKLGE 853
             AG Y     N  GE
Sbjct: 1338 HAGEYFCYVKNTAGE 1352


>SB_45852| Best HMM Match : I-set (HMM E-Value=0)
          Length = 1122

 Score = 87.0 bits (206), Expect = 3e-16
 Identities = 187/849 (22%), Positives = 312/849 (36%), Gaps = 161/849 (18%)

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161
            A  ++S  + DSG Y  VA N  G A  S+++T+  +  I+     + L  K   I    
Sbjct: 294  AFTLSSTESADSGRYDCVATNLKGTAMASSAITIHDK--IEKRVAPKILSSKKNLIA--- 348

Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221
                       S++K +F   +     + EGK++ L+C    +G P   V WF NG +VT
Sbjct: 349  -----------SENKRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVT 395

Query: 1222 VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQN 1281
                 K   + G  AL II  T+ + G+Y  ++ N  G    ++   V+           
Sbjct: 396  ESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVV----------- 442

Query: 1282 EQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQT 1341
                 +IQL          +++ +T++           + T+ GT   + C     G   
Sbjct: 443  GPVAPKIQLSNKVYSVVDPLKKPLTLLVG-------DTLTTLSGTRTSISC--PATGFPN 493

Query: 1342 MRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALR 1401
              + W  NG+ +  G   +     D   L L +   ED+GVY C A+N  G+A  +  + 
Sbjct: 494  PLIRWSRNGESVVPGGHLK----IDGSKLLLTNPQKEDNGVYKCLASNPGGDATATSNMT 549

Query: 1402 VIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQH 1461
             I       +  +P+       ++ T R   + II   VT              VI+G  
Sbjct: 550  FI-------DPSNPNITLSRDVVKSTIREAVSVIIGSDVT--------------VIDGST 588

Query: 1462 VHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
            +  +C    V        W +NG  ++               L + +L     G   C A
Sbjct: 589  ILIQCSAVGVPKPTF--SWIRNGVNLSNSEE----------VLKLSNLRVGGDGSIKCVA 636

Query: 1522 VNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVLEDRSKY--HRTDMVDEVTTQAPI 1579
             N  GTD     LT                     +LE R  +    +  +  + +  P+
Sbjct: 637  SNFYGTDSAETTLT---------------------ILEPRGPFIESSSQSLSSINSTDPV 675

Query: 1580 CTTSLKNVEIKEGQRAHFERRLIPVSDATLKV-EWYHNNKPLKSGSRFTETNNFGFVALD 1638
                  N+ +  G    F   +   +   + V  W +N+  + SG    + +     AL 
Sbjct: 676  RALIGSNLTVLAGA---FVTLVCNATGLPMPVASWKYNSGDITSGHVTIQGS-----ALR 727

Query: 1639 IMSCLPEDSGTYTCRAINALGE-AVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKY 1697
            I      DSG Y C A +  GE  VTS + ++             G++P + +  D  + 
Sbjct: 728  ITKTSNADSGVYACLARSPAGEVTVTSHLILI------------AGSIPVITRSADVIED 775

Query: 1698 QRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN 1757
            Q   +   V     V  +    I++              +G PK  V W   G P+  S+
Sbjct: 776  QSKFSNLTVTIGTKVTLLASSSIKIT----------CKAIGIPKPVVTWTMRGRPVVPSD 825

Query: 1758 RLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESA 1817
            R+    +    AL    +   D+G   C A N  G  V SS + V       L  Q++  
Sbjct: 826  RVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLITV---LGTYLRPQNQHC 878

Query: 1818 LQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMR 1877
             + I QL+    +Q     +V  +     +T L+G T           C+    P P   
Sbjct: 879  GKVITQLD----HQNPVTSKVGAS-----VTALSGVT-------VTLVCQAIGLPVPT-- 920

Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            + W FNGK L S  +   +N     ++ I+    EDSG+Y C A +  GQ  +   + ++
Sbjct: 921  ITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSVIKIE 976

Query: 1938 SKESIIRDS 1946
               S  ++S
Sbjct: 977  GLLSYKKNS 985



 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 121/468 (25%), Positives = 170/468 (36%), Gaps = 80/468 (17%)

Query: 1734 LIPV-GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            + PV G P  +V W +NG PI + ++ T       V  N    +  DSG Y+CRA+N LG
Sbjct: 159  ICPVEGLPPPKVTWAKNG-PIASGDKFTIARSTDLV-FNSGKASVFDSGRYSCRAVNNLG 216

Query: 1793 -EAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLN 1851
             +   S   F + KA              I  L+D          E  VN    F   + 
Sbjct: 217  QDTAYSEVTFREPKA------------PTIMTLDDK--------FEFIVNAT--FTVTIG 254

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
                   G S    C  E  P P   V W   G  LQ G R          A  + +   
Sbjct: 255  ANVSALRGSSITLTCTAEGLPVP--FVVWKKGGATLQQGGR----------AFTLSSTES 302

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDD 1971
             DSG Y C A N  G A++S  + +  K            +EK    +  S  K  +  +
Sbjct: 303  ADSGRYDCVATNLKGTAMASSAITIHDK------------IEKRVAPKILSSKKNLIASE 350

Query: 1972 SFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYD 2031
            +  +     G    N  + EG  + L+     +  P   V W+ NG  V +    K   +
Sbjct: 351  NKRLFYHIIG---GNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLKVDPN 405

Query: 2032 FGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQEL 2091
             G  AL I+   AE+ G YMCK+ N  GE + TS   V                 KIQ  
Sbjct: 406  TG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVVGPVA-----------PKIQLS 452

Query: 2092 EKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK 2151
             K           P ++P+ L    +L  L  G R    C      +P   I W  NG+ 
Sbjct: 453  NKV-----YSVVDPLKKPLTLLVGDTLTTL-SGTRTSISCPATGFPNP--LIRWSRNGES 504

Query: 2152 IRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
            +  G   +         L +     ED+G Y C A+N  G+A  T  +
Sbjct: 505  VVPGGHLKIDGS----KLLLTNPQKEDNGVYKCLASNPGGDATATSNM 548



 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 117/468 (25%), Positives = 181/468 (38%), Gaps = 73/468 (15%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P+  V+W RN V +    R    +   Y  +     N E SG Y C A N+ G A  +
Sbjct: 47   GFPQPIVQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGELSGEYACLATNKGGFAAVT 106

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857
            + L +++     + S   +      +L  S     R+ V V +      +T         
Sbjct: 107  TDLQIKAPFKPFIRSTWVTGSVGTHKLLKS-----RDPVIVTIGDKVETLT--------- 152

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT--SNDFGFAALDILTVYGEDSG 1915
             G      C +E  P P  +V W  NG +  SG ++    S D  F +    +V+  DSG
Sbjct: 153  -GTEVSIICPVEGLPPP--KVTWAKNGPIA-SGDKFTIARSTDLVFNS-GKASVF--DSG 205

Query: 1916 EYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVV 1975
             Y+C+A+NNLGQ  +   +  +           E     I  L+D   +   + + +F V
Sbjct: 206  RYSCRAVNNLGQDTAYSEVTFR-----------EPKAPTIMTLDDKFEF---IVNATFTV 251

Query: 1976 EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYV 2035
                 G    N     G  + L  T T    P   V W   G  +QQG R          
Sbjct: 252  T---IGA---NVSALRGSSITL--TCTAEGLPVPFVVWKKGGATLQQGGR---------- 293

Query: 2036 ALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYE 2095
            A  +    + D+G Y C ATN  G A+ +S++ +        D ++++   KI   +K  
Sbjct: 294  AFTLSSTESADSGRYDCVATNLKGTAMASSAITIH-------DKIEKRVAPKILSSKK-- 344

Query: 2096 RPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAG 2155
                I  E    + +F   +     + EG     +C    I  P   + WF NG  +   
Sbjct: 345  --NLIASEN---KRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTES 397

Query: 2156 HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
               +   + G  AL I+   AE+ G YMCK+ N  GE + T    V G
Sbjct: 398  DTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVVG 443



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 76/307 (24%), Positives = 118/307 (38%), Gaps = 48/307 (15%)

Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
           +G+    Q    G P+P  +W +NG  L NS +           L++ N +    G    
Sbjct: 585 DGSTILIQCSAVGVPKPTFSWIRNGVNLSNSEE----------VLKLSNLRVGGDGSIKC 634

Query: 339 LAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVC 398
           +A N  G       L +  P   +++   SQ ++     +             P    + 
Sbjct: 635 VASNFYGTDSAETTLTILEPRGPFIESS-SQSLSSINSTD-------------PVRALIG 680

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
            +  V  G      C  TG P P  +W  N   I   +     V   G+ AL IT  + +
Sbjct: 681 SNLTVLAGAFVTLVCNATGLPMPVASWKYNSGDITSGH-----VTIQGS-ALRITKTSNA 734

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE------RFSTLNVREGEPVVLNA 512
           DSGV  C+AR+ +GE      L +I     V  +  +      +FS L V  G  V L A
Sbjct: 735 DSGVYACLARSPAGEVTVTSHLILIAGSIPVITRSADVIEDQSKFSNLTVTIGTKVTLLA 794

Query: 513 --------RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
                   +A+G P P +TW   G P++P+  + +      + L   +  A+D     CT
Sbjct: 795 SSSIKITCKAIGIPKPVVTWTMRGRPVVPSDRVMVE----KNALVFLKILATDTGNVVCT 850

Query: 565 AQNVAGS 571
           A N  GS
Sbjct: 851 ANNARGS 857



 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 98/404 (24%), Positives = 151/404 (37%), Gaps = 48/404 (11%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P P + W + N PI +   F I   ST  +    +  V DS  ++  A N  G    
Sbjct: 163  EGLPPPKVTWAK-NGPIASGDKFTIAR-STDLVFNSGKASVFDSGRYSCRAVNNLGQDTA 220

Query: 4495 SANLVVEEKRR-------QGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
             + +   E +             IV  +FT+T   NV+   G  + L     G     V 
Sbjct: 221  YSEVTFREPKAPTIMTLDDKFEFIVNATFTVTIGANVSALRGSSITLTCTAEGLPVPFVV 280

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W K G  +Q   R         +TL   E+   DSG+Y+CVA N  G A   +   +   
Sbjct: 281  WKKGGATLQQGGR--------AFTLSSTES--ADSGRYDCVATNLKGTAMASSAITIHDK 330

Query: 4607 ATKD-KPKPQTKAANAPPEIIEPLKDKIVA------EGQAIEFSCKIVGKPLPTVQWYKG 4659
              K   PK  +   N      + L   I+       EG+ +E  C  +G P P V W+  
Sbjct: 331  IEKRVAPKILSSKKNLIASENKRLFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFIN 390

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR----------VTVAAK 4709
               +  S   ++        L I E   E++G Y C + N AG             VA K
Sbjct: 391  GSAVTESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVVGPVAPK 448

Query: 4710 LKVTQPDQADNLPALTPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
            ++++    +   P   PL  +V        G         T    P I+W R G  +   
Sbjct: 449  IQLSNKVYSVVDPLKKPLTLLVGDTLTTLSGTRTSISCPATGFPNPLIRWSRNGESV--V 506

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P   +  +G+   LL+ N  +ED G + C A+   G    ++ +
Sbjct: 507  PGGHLKIDGSK--LLLTNPQKEDNGVYKCLASNPGGDATATSNM 548



 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 65/277 (23%), Positives = 103/277 (37%), Gaps = 33/277 (11%)

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
           N  + EG D + Q    G P+P VTWF NG  +  S+  ++    N   L +      + 
Sbjct: 362 NITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV--DPNTGALSIIEITAEEQ 419

Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393
           G Y   ++N  G  + + Y  V  P    +Q     Y              + +    P 
Sbjct: 420 GQYMCKSKNIAGEDLETSYTTVVGPVAPKIQLSNKVY-------------SVVDPLKKPL 466

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            + V        G  T   C  TG P P + W  N   +    + KI         L++T
Sbjct: 467 TLLVGDTLTTLSGTRTSISCPATGFPNPLIRWSRNGESVVPGGHLKI-----DGSKLLLT 521

Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIE--------KEQVVAPKFVERFSTL----- 500
           N    D+GV  C+A N  G+      +  I+           VV     E  S +     
Sbjct: 522 NPQKEDNGVYKCLASNPGGDATATSNMTFIDPSNPNITLSRDVVKSTIREAVSVIIGSDV 581

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
            V +G  +++   AVG P P  +W ++GV +  + E+
Sbjct: 582 TVIDGSTILIQCSAVGVPKPTFSWIRNGVNLSNSEEV 618



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 85/415 (20%), Positives = 149/415 (35%), Gaps = 47/415 (11%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            + E +    +    G P P + W+     +  S   ++   +T ++ II ++  E+   +
Sbjct: 365  ILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDP-NTGALSII-EITAEEQGQY 422

Query: 4482 AAVAENRGG----------TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLV 4531
               ++N  G              +  + +  K       +  P   L    +   SG   
Sbjct: 423  MCKSKNIAGEDLETSYTTVVGPVAPKIQLSNKVYSVVDPLKKPLTLLVGDTLTTLSGTRT 482

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
             +    TG     + W +NG+ V P    KI   DG+  LL+     +D+G Y+C+A N 
Sbjct: 483  SISCPATGFPNPLIRWSRNGESVVPGGHLKI---DGS-KLLLTNPQKEDNGVYKCLASNP 538

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL--KDKIVAEGQAIEFSCKIVGK 4649
             G+A   +      P+  +    +    +   E +  +   D  V +G  I   C  VG 
Sbjct: 539  GGDATATSNMTFIDPSNPNITLSRDVVKSTIREAVSVIIGSDVTVIDGSTILIQCSAVGV 598

Query: 4650 PLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAK 4709
            P PT  W +    +  S          E  L++S      +G  KCVA N  G  +    
Sbjct: 599  PKPTFSWIRNGVNLSNS----------EEVLKLSNLRVGGDGSIKCVASNFYGTDSAETT 648

Query: 4710 LKVTQP---------DQADNLPALTPLRDIV-----VYEGQPAQFKTQITSKIKPTIQWL 4755
            L + +P             ++ +  P+R ++     V  G         T    P   W 
Sbjct: 649  LTILEPRGPFIESSSQSLSSINSTDPVRALIGSNLTVLAGAFVTLVCNATGLPMPVASWK 708

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                 I  T     I     + L I  T   D+G + C A + AG+V  ++ L++
Sbjct: 709  YNSGDI--TSGHVTIQ---GSALRITKTSNADSGVYACLARSPAGEVTVTSHLIL 758



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 69/320 (21%), Positives = 131/320 (40%), Gaps = 47/320 (14%)

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
           N  +  GA        +G P P  +W  N   + + +      T   + LR+  T  +DS
Sbjct: 682 NLTVLAGAFVTLVCNATGLPMPVASWKYNSGDITSGH-----VTIQGSALRITKTSNADS 736

Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKA--LA 391
           G Y  LA +P G +  + +L + + +   +   RS  + + Q + +   + I  K   LA
Sbjct: 737 GVYACLARSPAGEVTVTSHLILIAGSIPVIT--RSADVIEDQSKFSNLTVTIGTKVTLLA 794

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
              +K+               C+  G P P VTW +  R +    + +++V ++   AL+
Sbjct: 795 SSSIKIT--------------CKAIGIPKPVVTWTMRGRPVVP--SDRVMVEKN---ALV 835

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVI----EKEQVVAPKFVERF---------- 497
              +  +D+G V C A N  G       + V+      +     K + +           
Sbjct: 836 FLKILATDTGNVVCTANNARGSDVASSLITVLGTYLRPQNQHCGKVITQLDHQNPVTSKV 895

Query: 498 -STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
            +++    G  V L  +A+G P P ITW  +G P+  + ++ +       ++ I +A++ 
Sbjct: 896 GASVTALSGVTVTLVCQAIGLPVPTITWTFNGKPLTSHGQVTVTN----QSVTIIKARSE 951

Query: 557 DAAWYQCTAQNVAGSTATRA 576
           D+  Y C A +  G  + R+
Sbjct: 952 DSGDYVCNATSANGQGSARS 971



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 97/411 (23%), Positives = 153/411 (37%), Gaps = 51/411 (12%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P+++W R    +        +  +   ++I  +   E S  +A +A N+GG A  +
Sbjct: 47   GFPQPIVQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGELSGEYACLATNKGGFAAVT 106

Query: 4496 ANLVVEEK-----RRQGRGGIV---------PPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
             +L ++       R     G V          P        V   +G  V +   V G  
Sbjct: 107  TDLQIKAPFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKVETLTGTEVSIICPVEGLP 166

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
            P  V W KNG     D        D  +       +  DSG+Y C A+N+ G+    +E 
Sbjct: 167  PPKVTWAKNGPIASGDKFTIARSTDLVFNSGKASVF--DSGRYSCRAVNNLGQDTAYSEV 224

Query: 4602 VVSLPATKDKPKPQTK---AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
                P          K     NA   +        +  G +I  +C   G P+P V W K
Sbjct: 225  TFREPKAPTIMTLDDKFEFIVNATFTVTIGANVSAL-RGSSITLTCTAEGLPVPFVVWKK 283

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG------RVTVAAKL-K 4711
            G   ++     Q  R    +TL  +E+   D G Y CVA N  G       +T+  K+ K
Sbjct: 284  GGATLQ-----QGGRA---FTLSSTES--ADSGRYDCVATNLKGTAMASSAITIHDKIEK 333

Query: 4712 VTQP---DQADNLPALTPLR--------DIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
               P       NL A    R        +I + EG+  + +       KP + W   G+ 
Sbjct: 334  RVAPKILSSKKNLIASENKRLFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFINGSA 393

Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVV 4810
            + E+   ++  + N   L I     E+ G + C++   AG+ +ETS   VV
Sbjct: 394  VTESDTLKV--DPNTGALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVV 442



 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 120/536 (22%), Positives = 198/536 (36%), Gaps = 84/536 (15%)

Query: 3400 LEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWN 3459
            +ED ++  +  ++     K    T  + N   L +G         T    P   V+W  N
Sbjct: 2    VEDPVIHAEKATIRAVD-KVTSLTSSIGNAITLLKGSRVTLVCHATGFPQPI--VQWTRN 58

Query: 3460 GKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNII 3519
               L    R   +    + ++  +    E SGEY C A N  G A  T  ++++      
Sbjct: 59   KVDLTGRMRQLRYNVTHYGVIIDTRFNGELSGEYACLATNKGGFAAVTTDLQIKAPFKPF 118

Query: 3520 LESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFEC 3579
            + S    G  GT  K+  L+     + T+  + E+      T T   +I           
Sbjct: 119  IRSTWVTGSVGT-HKL--LKSRDPVIVTIGDKVET-----LTGTEVSIICPVEG------ 164

Query: 3580 RLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHG 3639
              +P      +V W  NG P+ +G +  TI     ++   G     D+G Y+C+A N  G
Sbjct: 165  --LP----PPKVTWAKNG-PIASGDKF-TIARSTDLVFNSGKASVFDSGRYSCRAVNNLG 216

Query: 3640 EATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTV 3699
            + T   ++  +       EP+ P+              TL  + E  +         FTV
Sbjct: 217  QDTAYSEVTFR-------EPKAPTIM------------TLDDKFEFIVN------ATFTV 251

Query: 3700 EIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDY 3759
             I  N+    G  +   C  E  G P   + W   G     G R  TL+           
Sbjct: 252  TIGANVSALRGSSITLTCTAE--GLPVPFVVWKKGGATLQQGGRAFTLSS---------- 299

Query: 3760 IYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDA 3819
              + D+G Y C ATN  G+A  ++ IT                   +KI++    +I  +
Sbjct: 300  TESADSGRYDCVATNLKGTAMASSAITIH-----------------DKIEKRVAPKILSS 342

Query: 3820 PKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR 3879
             K+  I S   +    I    +   EG   E +      PK  + W+ NG  +      +
Sbjct: 343  -KKNLIASENKRLFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLK 401

Query: 3880 TVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDF--TKATISCKKLPDIILQNQV 3933
               + G  +L I+ + AE+ G+Y+C++ N  GED   +  T+     P I L N+V
Sbjct: 402  VDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVVGPVAPKIQLSNKV 455



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 104/495 (21%), Positives = 171/495 (34%), Gaps = 64/495 (12%)

Query: 4349 DPSESTVHGKEVHVAKQKQ---TQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPV 4405
            DP+   +   E+   +Q Q     K + G+ ++    T T    +  K Q   +V    V
Sbjct: 403  DPNTGALSIIEITAEEQGQYMCKSKNIAGE-DLETSYT-TVVGPVAPKIQLSNKVYS-VV 459

Query: 4406 KPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTK 4465
             P K P+              +        G P PLI+W R    +      +I      
Sbjct: 460  DPLKKPLTLLVGDTLTTLSGTRTSISCPATGFPNPLIRWSRNGESVVPGGHLKIDG---- 515

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLV--------VEEKRRQGRGGIVPPSFT 4517
            S L++     ED+ V+  +A N GG A  ++N+         +   R   +  I      
Sbjct: 516  SKLLLTNPQKEDNGVYKCLASNPGGDATATSNMTFIDPSNPNITLSRDVVKSTIREAVSV 575

Query: 4518 LTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY 4577
            +   +V V  G  + +     G       W++NG  +         EE     L +    
Sbjct: 576  IIGSDVTVIDGSTILIQCSAVGVPKPTFSWIRNGVNLSNS------EE----VLKLSNLR 625

Query: 4578 PQDSGKYECVAINSAGEARCDAECVVSLPATK--DKPKPQTKAANAPPEIIEPLKDKI-V 4634
                G  +CVA N  G    +    +  P     +       + N+   +   +   + V
Sbjct: 626  VGGDGSIKCVASNFYGTDSAETTLTILEPRGPFIESSSQSLSSINSTDPVRALIGSNLTV 685

Query: 4635 AEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
              G  +   C   G P+P   W Y    +       Q S       LRI++    D G Y
Sbjct: 686  LAGAFVTLVCNATGLPMPVASWKYNSGDITSGHVTIQGS------ALRITKTSNADSGVY 739

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI----- 4748
             C+A + AG VTV + L +     A ++P +T   D++  + + +     I +K+     
Sbjct: 740  ACLARSPAGEVTVTSHLILI----AGSIPVITRSADVIEDQSKFSNLTVTIGTKVTLLAS 795

Query: 4749 -------------KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA 4795
                         KP + W   G   P  P  +++ E N  V L       DTG   C A
Sbjct: 796  SSIKITCKAIGIPKPVVTWTMRGR--PVVPSDRVMVEKNALVFL--KILATDTGNVVCTA 851

Query: 4796 TTAAGQVETSAKLVV 4810
              A G    S+ + V
Sbjct: 852  NNARGSDVASSLITV 866



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 75/343 (21%), Positives = 123/343 (35%), Gaps = 49/343 (14%)

Query: 250 VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS 309
           +Q+S ++   + P+  P             G         +G P P + W +NG+ ++  
Sbjct: 449 IQLSNKVYSVVDPLKKPLTLLVGDTLTTLSGTRTSISCPATGFPNPLIRWSRNGESVVPG 508

Query: 310 NKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQ 369
              +I    + + L + N QK D+G Y  LA NP G    +  +    P+   +   R  
Sbjct: 509 GHLKI----DGSKLLLTNPQKEDNGVYKCLASNPGGDATATSNMTFIDPSNPNITLSR-- 562

Query: 370 YITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIND 429
              D  +    E +           V +  D  V +G      C   G P P  +W    
Sbjct: 563 ---DVVKSTIREAVS----------VIIGSDVTVIDGSTILIQCSAVGVPKPTFSW---- 605

Query: 430 RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489
             IR+  N   L N      L ++N+ +   G + CVA N  G  + +  L ++E     
Sbjct: 606 --IRNGVN---LSN--SEEVLKLSNLRVGGDGSIKCVASNFYGTDSAETTLTILEPRGPF 658

Query: 490 APKFVERFSTLN--------------VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP 535
                +  S++N              V  G  V L   A G P P  +W+ +   I    
Sbjct: 659 IESSSQSLSSINSTDPVRALIGSNLTVLAGAFVTLVCNATGLPMPVASWKYNSGDITSG- 717

Query: 536 ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
               H     S L I +   +D+  Y C A++ AG     + L
Sbjct: 718 ----HVTIQGSALRITKTSNADSGVYACLARSPAGEVTVTSHL 756



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 106/452 (23%), Positives = 166/452 (36%), Gaps = 71/452 (15%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            V+W  N   +T   R   Y+   Y  +       E SG Y  +A N  G A ++  + ++
Sbjct: 53   VQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGELSGEYACLATNKGGFAAVTTDLQIK 112

Query: 1137 TRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIH 1196
                              +    S +V       ++ KS+   +  + +      G  + 
Sbjct: 113  A---------------PFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKVETLTGTEVS 157

Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256
            + C +E  G P  +V W  NG  +  G +F        V  +   A+  D+G Y+ RAVN
Sbjct: 158  IICPVE--GLPPPKVTWAKNG-PIASGDKFTIARSTDLV-FNSGKASVFDSGRYSCRAVN 213

Query: 1257 HLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRA 1316
            +LG     + V           T  E     I  L+D           +T+         
Sbjct: 214  NLGQDTAYSEV-----------TFREPKAPTIMTLDDKFEFIVNATFTVTIGA------- 255

Query: 1317 LHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVY 1376
              N+  + G+++ L C  +  G     V W   G  ++ G R          A  L S  
Sbjct: 256  --NVSALRGSSITLTCTAE--GLPVPFVVWKKGGATLQQGGR----------AFTLSSTE 301

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDII 1436
              DSG Y C ATN  G A+ S A+ +    D I +   P  L            KK  I 
Sbjct: 302  SADSGRYDCVATNLKGTAMASSAITI---HDKIEKRVAPKILSS----------KKNLIA 348

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
             E+   K  F         ++EG+ +  +C    +      V WF NG  VT     +  
Sbjct: 349  SEN---KRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLKVD 403

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             + G  AL II++ AE+ G Y C++ N+ G D
Sbjct: 404  PNTG--ALSIIEITAEEQGQYMCKSKNIAGED 433



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 72/311 (23%), Positives = 110/311 (35%), Gaps = 52/311 (16%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
           G +      + G P P+VTW KNG   I S     I                DSG Y+  
Sbjct: 153 GTEVSIICPVEGLPPPKVTWAKNGP--IASGDKFTIARSTDLVFNSGKASVFDSGRYSCR 210

Query: 340 AENPNGCIVTSGYLAVESPTESYVQ--DQRSQYITDTQQRETEERIEISEKALAPQFVKV 397
           A N  G       +    P    +   D + ++I +     T   I  +  AL       
Sbjct: 211 AVNNLGQDTAYSEVTFREPKAPTIMTLDDKFEFIVNATFTVT---IGANVSAL------- 260

Query: 398 CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTL 457
                   G      C   G P P V W      +           + G  A  +++   
Sbjct: 261 -------RGSSITLTCTAEGLPVPFVVWKKGGATL-----------QQGGRAFTLSSTES 302

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEK-EQVVAPKFVERFSTL---------------- 500
           +DSG   CVA N  G       + + +K E+ VAPK +     L                
Sbjct: 303 ADSGRYDCVATNLKGTAMASSAITIHDKIEKRVAPKILSSKKNLIASENKRLFYHIIGGN 362

Query: 501 -NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
             + EG+ + L   ++GTP P +TW  +G  +  +  L++  + GA  L I    A +  
Sbjct: 363 ITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTGA--LSIIEITAEEQG 420

Query: 560 WYQCTAQNVAG 570
            Y C ++N+AG
Sbjct: 421 QYMCKSKNIAG 431



 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 146/614 (23%), Positives = 235/614 (38%), Gaps = 101/614 (16%)

Query: 1320 IETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYP-E 1378
            I  ++G+ V L C     G     V+W  N K   TG   +  Y   +  + + + +  E
Sbjct: 31   ITLLKGSRVTLVCHA--TGFPQPIVQWTRN-KVDLTGRMRQLRYNVTHYGVIIDTRFNGE 87

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDE 1438
             SG Y C ATN+ G A  +  L++ A     + S   +G      L      K  D    
Sbjct: 88   LSGEYACLATNKGGFAAVTTDLQIKAPFKPFIRSTWVTGSVGTHKL-----LKSRD---- 138

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
                 P  VT    +E  + G  V   C +E +     KV W KNG P+  G +F     
Sbjct: 139  -----PVIVTIGDKVET-LTGTEVSIICPVEGLPPP--KVTWAKNG-PIASGDKFTIARS 189

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQIQVL 1558
               V  +       DSG Y+CRAVN +G D     +T R           E     I  L
Sbjct: 190  TDLV-FNSGKASVFDSGRYSCRAVNNLGQDTAYSEVTFR-----------EPKAPTIMTL 237

Query: 1559 EDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNK 1618
            +D+ ++   +    VT  A +  ++L+   I     A  E   +P       V W     
Sbjct: 238  DDKFEF-IVNATFTVTIGANV--SALRGSSITLTCTA--EGLPVPF------VVWKKGGA 286

Query: 1619 PLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLE 1678
             L+ G R          A  + S    DSG Y C A N  G A+ S    +H K    +E
Sbjct: 287  TLQQGGR----------AFTLSSTESADSGRYDCVATNLKGTAMASSAITIHDK----IE 332

Query: 1679 SQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVG 1738
             +     P++     +SK    +++++ +     + +   +I + E +    E +   +G
Sbjct: 333  KR---VAPKIL----SSKKNLIASENKRL----FYHIIGGNITILEGK--DLELQCPSIG 379

Query: 1739 DPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
             PK  V W  NG  +  S+ L    + G  AL++  +  E+ G Y C++ N  GE     
Sbjct: 380  TPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGE----- 432

Query: 1799 TLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS- 1857
                       LE+ + + +  +     + + Q    V   V+   + +T L G T  + 
Sbjct: 433  ----------DLETSYTTVVGPV-----APKIQLSNKVYSVVDPLKKPLTLLVGDTLTTL 477

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEY 1917
             G      C    +P+P +R  W  NG+ +  G   +       + L +     ED+G Y
Sbjct: 478  SGTRTSISCPATGFPNPLIR--WSRNGESVVPGGHLKIDG----SKLLLTNPQKEDNGVY 531

Query: 1918 TCKAINNLGQAVSS 1931
             C A N  G A ++
Sbjct: 532  KCLASNPGGDATAT 545



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 180/848 (21%), Positives = 296/848 (34%), Gaps = 159/848 (18%)

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDAS 1027
            A T+ S    D+G Y C A N  G A  S+ +TI  K            +EK      A 
Sbjct: 294  AFTLSSTESADSGRYDCVATNLKGTAMASSAITIHDK------------IEK----RVAP 337

Query: 1028 RYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQIT 1087
            +     +  +    K  F   + G   I+EG+    E +          V W+ NG  +T
Sbjct: 338  KILSSKKNLIASENKRLFYHIIGGNITILEGKD--LELQCPSIGTPKPAVTWFINGSAVT 395

Query: 1088 SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIH 1147
             ++ ++   + G  AL I  + AE+ G Y   ++N AGE  L  S T           + 
Sbjct: 396  ESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGE-DLETSYTTVVGPVAPKIQLS 452

Query: 1148 RGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDP 1207
              +Y           V+P+         KP+ +  + +      G    + C     G P
Sbjct: 453  NKVY---------SVVDPL--------KKPLTLL-VGDTLTTLSGTRTSISC--PATGFP 492

Query: 1208 TMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIV 1267
               + W  NG SV  G   K         L + +    D G Y   A N  G A  ++ +
Sbjct: 493  NPLIRWSRNGESVVPGGHLK----IDGSKLLLTNPQKEDNGVYKCLASNPGGDATATSNM 548

Query: 1268 RVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTN 1327
              I+ S+             I L  D  + T  +RE ++V+          ++  ++G+ 
Sbjct: 549  TFIDPSN-----------PNITLSRDVVKST--IREAVSVIIG-------SDVTVIDGST 588

Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQA 1387
            + ++C    VG       W  NG  +                L L ++     G   C A
Sbjct: 589  ILIQC--SAVGVPKPTFSWIRNGVNLSNSEE----------VLKLSNLRVGGDGSIKCVA 636

Query: 1388 TNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPRFV 1447
            +N  G       L ++  +   +ES   S    +  +  T   +   +I  ++T      
Sbjct: 637  SNFYGTDSAETTLTILEPRGPFIESSSQS----LSSINSTDPVRA--LIGSNLT------ 684

Query: 1448 TRPKSIENVIEGQHVHFECKLEPVTDSNLKV-EWFKNGQPVTIGHRFRPIHDFGYVALDI 1506
                    V+ G  V   C     T   + V  W  N   +T GH    +   G  AL I
Sbjct: 685  --------VLAGAFVTLVCN---ATGLPMPVASWKYNSGDITSGH----VTIQG-SALRI 728

Query: 1507 IDLIAEDSGIYTCRAVNLVGTDEVSCR--LTCRSTTDIVRSTQNEAGLEQIQVLEDRSKY 1564
                  DSG+Y C A +  G   V+    L   S   I RS           V+ED+SK+
Sbjct: 729  TKTSNADSGVYACLARSPAGEVTVTSHLILIAGSIPVITRSA---------DVIEDQSKF 779

Query: 1565 HRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGS 1624
              +++   + T+  +  +S   +  K             +      V W    +P+    
Sbjct: 780  --SNLTVTIGTKVTLLASSSIKITCK------------AIGIPKPVVTWTMRGRPVVPSD 825

Query: 1625 RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGA 1684
            R     N    AL  +  L  D+G   C A NA G  V S +  V      YL  Q++  
Sbjct: 826  RVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLITV---LGTYLRPQNQHC 878

Query: 1685 LPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRV 1744
               + QL+          Q+ V ++       +  + V     A        +G P   +
Sbjct: 879  GKVITQLDH---------QNPVTSKVGASVTALSGVTVTLVCQA--------IGLPVPTI 921

Query: 1745 EWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
             W  NG P+ +  ++T  +     ++ +     EDSG Y C A +  G+    S + ++ 
Sbjct: 922  TWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSVIKIEG 977

Query: 1805 KASLQLES 1812
              S +  S
Sbjct: 978  LLSYKKNS 985



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 70/306 (22%), Positives = 119/306 (38%), Gaps = 21/306 (6%)

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAY--PQD 4580
            + +  G  V L    TG     V W +N  KV    R + L  + T+  +I++     + 
Sbjct: 31   ITLLKGSRVTLVCHATGFPQPIVQWTRN--KVDLTGRMRQLRYNVTHYGVIIDTRFNGEL 88

Query: 4581 SGKYECVAINSAGEARCDAECVVSLP------ATKDKPKPQT-KAANAPPEIIEPLKDKI 4633
            SG+Y C+A N  G A    +  +  P      +T       T K   +   +I  + DK+
Sbjct: 89   SGEYACLATNKGGFAAVTTDLQIKAPFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKV 148

Query: 4634 -VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
                G  +   C + G P P V W K   +    K F ++R+ D       +A   D G 
Sbjct: 149  ETLTGTEVSIICPVEGLPPPKVTWAKNGPIASGDK-FTIARSTD-LVFNSGKASVFDSGR 206

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS--KIKP 4750
            Y C A N+ G+ T  +++   +P +A  +  L    + +V           +++      
Sbjct: 207  YSCRAVNNLGQDTAYSEVTFREP-KAPTIMTLDDKFEFIVNATFTVTIGANVSALRGSSI 265

Query: 4751 TIQWLREGALIPET---PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
            T+    EG  +P          + +G  A  L  +T   D+G + C AT   G    S+ 
Sbjct: 266  TLTCTAEGLPVPFVVWKKGGATLQQGGRAFTL-SSTESADSGRYDCVATNLKGTAMASSA 324

Query: 4808 LVVKSK 4813
            + +  K
Sbjct: 325  ITIHDK 330



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 69/309 (22%), Positives = 116/309 (37%), Gaps = 37/309 (11%)

Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH-EIITTHNHTTLRVRNTQKSDSGH 335
           L +G+        +G P+P V W +N   L    +      TH    +  R   +  SG 
Sbjct: 33  LLKGSRVTLVCHATGFPQPIVQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGEL-SGE 91

Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395
           Y  LA N  G    +  L +++P + ++   RS ++T +    T + +    K+  P  V
Sbjct: 92  YACLATNKGGFAAVTTDLQIKAPFKPFI---RSTWVTGSVG--THKLL----KSRDPVIV 142

Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
            +    +   G      C V G P P+VTW  N      D   K  +  S +        
Sbjct: 143 TIGDKVETLTGTEVSIICPVEGLPPPKVTWAKNGPIASGD---KFTIARSTDLVFNSGKA 199

Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-------------STLNV 502
           ++ DSG  +C A N  G+      +   E +        ++F             + ++ 
Sbjct: 200 SVFDSGRYSCRAVNNLGQDTAYSEVTFREPKAPTIMTLDDKFEFIVNATFTVTIGANVSA 259

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             G  + L   A G P P + W+K G          +   G A TL     +++D+  Y 
Sbjct: 260 LRGSSITLTCTAEGLPVPFVVWKKGGA--------TLQQGGRAFTLS--STESADSGRYD 309

Query: 563 CTAQNVAGS 571
           C A N+ G+
Sbjct: 310 CVATNLKGT 318



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 92/436 (21%), Positives = 166/436 (38%), Gaps = 59/436 (13%)

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            ++ T   DSG Y C ATN KG+A  S ++           T H       + +E+    +
Sbjct: 297  LSSTESADSGRYDCVATNLKGTAMASSAI-----------TIH-------DKIEKRVAPK 338

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
            +   ++  +      K  +   I     ++EG+ L L  Q      P   + W+ NG  +
Sbjct: 339  ILSSKKNLIASEN--KRLFYHIIGGNITILEGKDLEL--QCPSIGTPKPAVTWFINGSAV 394

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQ 3014
             +    K+  + G   L ++++   + G Y CK+ N  GE   +S  Y T    +  + Q
Sbjct: 395  TESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETS--YTTVVGPVAPKIQ 450

Query: 3015 HPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIP 3074
                     K+ ++ D L+K                T +  D +    G       S   
Sbjct: 451  LSN------KVYSVVDPLKKP--------------LTLLVGDTLTTLSG--TRTSISCPA 488

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG  + +I W  NG+++     ++     G  +L +   +  D+G Y C A+N  G A  
Sbjct: 489  TGFPNPLIRWSRNGESVVPGGHLKID---GSKLL-LTNPQKEDNGVYKCLASNPGGDATA 544

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEG-LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
            +  +  +D S    P  T     ++  +++  S      V  +D   + I+    G P  
Sbjct: 545  TSNMTFIDPS---NPNITLSRDVVKSTIREAVSVIIGSDVTVIDGSTILIQCSAVGVPKP 601

Query: 3194 HSTRIKTVSDF--GFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251
              + I+   +      VL ++  +    G   C A N YG D    T+      G ++ES
Sbjct: 602  TFSWIRNGVNLSNSEEVLKLSNLRVGGDGSIKCVASNFYGTDSAETTLTILEPRGPFIES 661

Query: 3252 LQPDSLAKIRELESLQ 3267
                SL+ I   + ++
Sbjct: 662  -SSQSLSSINSTDPVR 676



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 67/293 (22%), Positives = 124/293 (42%), Gaps = 32/293 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P+P+  W   +  I +      H     S L I +    DS V+A +A +  G    +
Sbjct: 699  GLPMPVASWKYNSGDITSG-----HVTIQGSALRITKTSNADSGVYACLARSPAGEVTVT 753

Query: 4496 ANLVVEEKR----RQGRGGIVPPS----FTLT-AQNVNVTSGQLVRLDTKVTGT-KPIDV 4545
            ++L++         +    I   S     T+T    V + +   +++  K  G  KP+ V
Sbjct: 754  SHLILIAGSIPVITRSADVIEDQSKFSNLTVTIGTKVTLLASSSIKITCKAIGIPKPV-V 812

Query: 4546 YWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSL 4605
             W   G+ V P   ++++ E     L+ L+    D+G   C A N+ G     A  ++++
Sbjct: 813  TWTMRGRPVVPS--DRVMVEKNA--LVFLKILATDTGNVVCTANNARGSDV--ASSLITV 866

Query: 4606 PATKDKPKPQ------TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
              T  +P+ Q      T+  +  P   +         G  +   C+ +G P+PT+ W   
Sbjct: 867  LGTYLRPQNQHCGKVITQLDHQNPVTSKVGASVTALSGVTVTLVCQAIGLPVPTITWTFN 926

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             K +  + + Q++ T    T  I +A  ED GDY C A ++ G+ +  + +K+
Sbjct: 927  GKPL--TSHGQVTVTNQSVT--IIKARSEDSGDYVCNATSANGQGSARSVIKI 975



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 57/207 (27%), Positives = 84/207 (40%), Gaps = 27/207 (13%)

Query: 1997 LEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
            ++ T   +  P   V W   GRPV    R     +    AL  L   A DTG  +C A N
Sbjct: 798  IKITCKAIGIPKPVVTWTMRGRPVVPSDRVMVEKN----ALVFLKILATDTGNVVCTANN 853

Query: 2057 AVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALT 2116
            A G  V +S + V    G YL   ++   K I +L+              Q PV      
Sbjct: 854  ARGSDVASSLITV---LGTYLRPQNQHCGKVITQLDH-------------QNPVTSKVGA 897

Query: 2117 SLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA 2176
            S+  L  G      C  + I  P  TI W  NG+ + +  +   T+     ++ I+   +
Sbjct: 898  SVTAL-SGVTVTLVC--QAIGLPVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARS 950

Query: 2177 EDSGTYMCKATNKLGEAVNTCTLKVAG 2203
            EDSG Y+C AT+  G+      +K+ G
Sbjct: 951  EDSGDYVCNATSANGQGSARSVIKIEG 977



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 128/623 (20%), Positives = 212/623 (34%), Gaps = 99/623 (15%)

Query: 1839 AVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSND 1898
            AV++     + +     L +G      C    +P P   V+W  N   L    R    N 
Sbjct: 16   AVDKVTSLTSSIGNAITLLKGSRVTLVCHATGFPQPI--VQWTRNKVDLTGRMRQLRYNV 73

Query: 1899 FGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSK-ESIIRDSQHESALEKIQY 1957
              +  +      GE SGEY C A N  G A  +  L +++  +  IR +    ++     
Sbjct: 74   THYGVIIDTRFNGELSGEYACLATNKGGFAAVTTDLQIKAPFKPFIRSTWVTGSV----- 128

Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND-PTMRVEWYCN 2016
                  +K     D  +V     G  ++    TE       + + PV   P  +V W  N
Sbjct: 129  ----GTHKLLKSRDPVIV---TIGDKVETLTGTE------VSIICPVEGLPPPKVTWAKN 175

Query: 2017 GRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLY 2076
            G P+  G +F        V  +   A   D+G Y C+A N +G+    S V         
Sbjct: 176  G-PIASGDKFTIARSTDLV-FNSGKASVFDSGRYSCRAVNNLGQDTAYSEVTFREPKAPT 233

Query: 2077 LDTLDEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPI 2136
            + TLD          +K+E               F   + +  +   G      C  E +
Sbjct: 234  IMTLD----------DKFEFI---------VNATFTVTIGANVSALRGSSITLTCTAEGL 274

Query: 2137 NDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNT 2196
              P +   W   G  ++ G R          A  +  T + DSG Y C ATN  G A+ +
Sbjct: 275  PVPFVV--WKKGGATLQQGGR----------AFTLSSTESADSGRYDCVATNLKGTAMAS 322

Query: 2197 CTLKVAGHRNIILDTQHPNGLEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFE 2256
              +           T H    +++           I  E  ++    F   + G   + E
Sbjct: 323  SAI-----------TIHDKIEKRVAPKILSSKKNLIASENKRL----FYHIIGGNITILE 367

Query: 2257 GKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYS 2316
            GK    +C    +  P   + ++ NG A+  +    +  + G  +L I     E+ G+Y 
Sbjct: 368  GKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEITAEEQGQYM 423

Query: 2317 VKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPEIPEPVTRQRP 2376
             K+ N  G        TV   G +  + Q    +  +      +P K+P           
Sbjct: 424  CKSKNIAGEDLETSYTTVV--GPVAPKIQLSNKVYSV-----VDPLKKP----------- 465

Query: 2377 VFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSM 2436
              T  + +      G      C     G P   + W RN + +     +          +
Sbjct: 466  -LTLLVGDTLTTLSGTRTSISCP--ATGFPNPLIRWSRNGESVVPGGHL----KIDGSKL 518

Query: 2437 TISHVRDEDEGVYMCRASNLLGE 2459
             +++ + ED GVY C ASN  G+
Sbjct: 519  LLTNPQKEDNGVYKCLASNPGGD 541



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 49/220 (22%), Positives = 89/220 (40%), Gaps = 28/220 (12%)

Query: 3940 SEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAP 3999
            S A+T  +   K+   ++  ++ +L   + K+   F   I    +++E +  + +C    
Sbjct: 322  SSAITIHDKIEKRVAPKILSSKKNLIASENKR--LFYHIIGGNITILEGKDLELQCP--S 377

Query: 4000 VGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDET 4059
            +G P   V WF NG  +   +  T   D    A++   +  E+ G+Y+C++ N+ G D  
Sbjct: 378  IGTPKPAVTWFINGSAVTESD--TLKVDPNTGALSIIEITAEEQGQYMCKSKNIAGEDLE 435

Query: 4060 KAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDA 4119
             +     G   +    QL   + S                 VV+  K    P+ + + D 
Sbjct: 436  TSYTTVVGP--VAPKIQLSNKVYS-----------------VVDPLK---KPLTLLVGDT 473

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            +T   G      C  TG P P + W  NG ++V G   K+
Sbjct: 474  LTTLSGTRTSISCPATGFPNPLIRWSRNGESVVPGGHLKI 513



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 65/244 (26%), Positives = 94/244 (38%), Gaps = 34/244 (13%)

Query: 3682 REEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG 3741
            R    IED+       TV I   + +     +   C+   +G P   + W   GRP    
Sbjct: 768  RSADVIEDQSKFS-NLTVTIGTKVTLLASSSIKITCKA--IGIPKPVVTWTMRGRPVVPS 824

Query: 3742 SRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQL-P 3800
             RV    +    AL    I A D G   C A N  GS   ++ IT       VL + L P
Sbjct: 825  DRVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLIT-------VLGTYLRP 873

Query: 3801 QGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPK 3860
            Q     K+       I+    + P+ S     +T +   TV         C+      P 
Sbjct: 874  QNQHCGKV-------ITQLDHQNPVTSKVGASVTALSGVTVT------LVCQAIGLPVPT 920

Query: 3861 LRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATIS 3920
              I W  NGK L S H   TV +    S+ I+   +EDSG+Y+C A +  G+   ++ I 
Sbjct: 921  --ITWTFNGKPLTS-HGQVTVTNQ---SVTIIKARSEDSGDYVCNATSANGQGSARSVIK 974

Query: 3921 CKKL 3924
             + L
Sbjct: 975  IEGL 978



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 68/303 (22%), Positives = 114/303 (37%), Gaps = 45/303 (14%)

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494
            + T+S     D G Y C A+NL G                   T H     KI+K   P 
Sbjct: 294  AFTLSSTESADSGRYDCVATNLKGTAMASSAI-----------TIHD----KIEKRVAPK 338

Query: 2495 ERRSEEPDREFE-KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
               S++     E K +F  ++ G   + EG+    E +   +G P     W+ING  +  
Sbjct: 339  ILSSKKNLIASENKRLFYHIIGGNITILEGKDL--ELQCPSIGTPKPAVTWFINGSAVTE 396

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXXXXXXXXXXXXIIDQAMRP 2613
                +   + G   L I  + A + G YMCK+ N AG                    + P
Sbjct: 397  SDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTT----------VVGP 444

Query: 2614 ESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPN 2673
             +  +IQL     + V  +     +      TT        + G    +        +P 
Sbjct: 445  VA-PKIQLSNKVYSVVDPLKKPLTLLVGDTLTT--------LSGTRTSISCPATGFPNPL 495

Query: 2674 LKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIK 2733
            ++  W +NG ++  G  LK         L + + + +D+G+Y C A+N  G+A +T+++ 
Sbjct: 496  IR--WSRNGESVVPGGHLKIDGS----KLLLTNPQKEDNGVYKCLASNPGGDATATSNMT 549

Query: 2734 IED 2736
              D
Sbjct: 550  FID 552



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 53/213 (24%), Positives = 80/213 (37%), Gaps = 31/213 (14%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            FT  + +    + G  + L    E    P   + W K G TL  G R            +
Sbjct: 249  FTVTIGANVSALRGSSITLTCTAEGLPVPF--VVWKKGGATLQQGGR----------AFT 296

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXX 2763
            ++S  + DSG Y C ATNL G A+++++I I D+   + + + P  L     L       
Sbjct: 297  LSSTESADSGRYDCVATNLKGTAMASSAITIHDK---IEKRVAPKILSSKKNLIASENKR 353

Query: 2764 XXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPS-RDPTLKIEWFFNNKPLPSGTRY 2822
                              NI   EG ++  +C   PS   P   + WF N   +      
Sbjct: 354  LFYHIIG----------GNITILEGKDLELQC---PSIGTPKPAVTWFINGSAVTESDTL 400

Query: 2823 KSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            K   D +  +L I     E+ G Y CK+ N  G
Sbjct: 401  KV--DPNTGALSIIEITAEEQGQYMCKSKNIAG 431



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 29/204 (14%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W   GRPV  S R+    N    AL    +   D G+  C A NA G    S+ +T++
Sbjct: 812  VTWTMRGRPVVPSDRVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLITVL 867

Query: 1003 TKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAH 1062
                +  ++QH G +  I  L+  +  + +    V           L G    +  Q+  
Sbjct: 868  GTY-LRPQNQHCGKV--ITQLDHQNPVTSKVGASVTA---------LSGVTVTLVCQAIG 915

Query: 1063 FEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
                         T+ W FNGK +TS  ++   +     ++ I   R+EDSG Y   A +
Sbjct: 916  LPVP---------TITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATS 962

Query: 1123 AAGEAQLSASMTVETRSSIDTSSI 1146
            A G+    + + +E   S   +S+
Sbjct: 963  ANGQGSARSVIKIEGLLSYKKNSV 986



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 77/308 (25%), Positives = 117/308 (37%), Gaps = 60/308 (19%)

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALE 3539
            L I+ T   DSG Y C A +  GE   T+ +       I++   +P      I + A   
Sbjct: 726  LRITKTSNADSGVYACLARSPAGEVTVTSHL-------ILIAGSIP-----VITRSA--- 770

Query: 3540 GYSGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKP 3599
                  D +  +++  N     T  + + L  +SS    C+ I +      V W   G+P
Sbjct: 771  ------DVIEDQSKFSNLT--VTIGTKVTLLASSSIKITCKAIGIPKPV--VTWTMRGRP 820

Query: 3600 LLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            ++   RV  +     V L+I      D G   C A N  G    S  + V G     L P
Sbjct: 821  VVPSDRVM-VEKNALVFLKI---LATDTGNVVCTANNARGSDVASSLITVLGTY---LRP 873

Query: 3660 QLPSHFKSGTESIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRV 3719
            Q                   H  + IT  D + NP   T ++  ++    G  V   C+ 
Sbjct: 874  Q-----------------NQHCGKVITQLDHQ-NP--VTSKVGASVTALSGVTVTLVCQA 913

Query: 3720 EPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT--NKWG 3777
              +G P   I W  NG+P  +  +V   N     ++ I    + D+G+Y C AT  N  G
Sbjct: 914  --IGLPVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQG 967

Query: 3778 SATTTAKI 3785
            SA +  KI
Sbjct: 968  SARSVIKI 975



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 6/78 (7%)

Query: 3990 TTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCR 4049
            T    CQ   +G P   + W FNGKPL    + T        ++       EDSG+Y+C 
Sbjct: 906  TVTLVCQA--IGLPVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCN 959

Query: 4050 ATNLYGMDETKAVIKTTG 4067
            AT+  G    ++VIK  G
Sbjct: 960  ATSANGQGSARSVIKIEG 977



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 41/139 (29%), Positives = 59/139 (42%), Gaps = 19/139 (13%)

Query: 4041 EDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKIREMEASWQVTPEQ 4100
            E SGEY C ATN  G     A + T        D Q+    K    IR    +  V   +
Sbjct: 87   ELSGEYACLATNKGGF----AAVTT--------DLQIKAPFKPF--IRSTWVTGSVGTHK 132

Query: 4101 VVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            ++   K+R  PV V++ D V    G      C V G P P+V W  NG  I +G ++ + 
Sbjct: 133  LL---KSR-DPVIVTIGDKVETLTGTEVSIICPVEGLPPPKVTWAKNG-PIASGDKFTIA 187

Query: 4161 YDGMYHFDIPKTRQYDTGK 4179
                  F+  K   +D+G+
Sbjct: 188  RSTDLVFNSGKASVFDSGR 206



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 67/302 (22%), Positives = 117/302 (38%), Gaps = 50/302 (16%)

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSS 1828
            AL +   +  DSG Y C A +  GE   +S L + +  S+ + ++    +      ED S
Sbjct: 725  ALRITKTSNADSGVYACLARSPAGEVTVTSHLILIA-GSIPVITRSADVI------EDQS 777

Query: 1829 RYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ 1888
            ++    ++ V +       T++     L    S    C+    P P   V W   G+ + 
Sbjct: 778  KFS---NLTVTIG------TKVT----LLASSSIKITCKAIGIPKPV--VTWTMRGRPVV 822

Query: 1889 SGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
               R     +    AL  L +   D+G   C A N  G  V+S  + V    + +R  Q+
Sbjct: 823  PSDRVMVEKN----ALVFLKILATDTGNVVCTANNARGSDVASSLITVLG--TYLRP-QN 875

Query: 1949 ESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPT 2008
            +   + I  L+  +     V                  A VT    V +      +  P 
Sbjct: 876  QHCGKVITQLDHQNPVTSKV-----------------GASVTALSGVTVTLVCQAIGLPV 918

Query: 2009 MRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVK 2068
              + W  NG+P+    +   T      ++ I+ A +ED+G Y+C AT+A G+    S +K
Sbjct: 919  PTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSVIK 974

Query: 2069 VD 2070
            ++
Sbjct: 975  IE 976



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 6/94 (6%)

Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704
           SVTA+ G  +      + +G P   I W  NG+ + +  + T   +    S+ ++    +
Sbjct: 898 SVTALSGVTVTLVC--QAIGLPVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSE 951

Query: 705 DSGEYTCRAVSATGVAETKAVLHVTPRATIERTS 738
           DSG+Y C A SA G    ++V+ +    + ++ S
Sbjct: 952 DSGDYVCNATSANGQGSARSVIKIEGLLSYKKNS 985



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P   I W FN KPL S  +   T+     S+ I     EDSG Y C AT++ G  +    
Sbjct: 917  PVPTITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSV 972

Query: 2863 LRCTG 2867
            ++  G
Sbjct: 973  IKIEG 977



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 20/175 (11%)

Query: 3081 VIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLEC 3140
            V+ W   G+ +  S R+  V    +V L+IL T   D+G   C A N  G    S  +  
Sbjct: 811  VVTWTMRGRPVVPSDRVM-VEKNALVFLKILAT---DTGNVVCTANNARGSDVASSLITV 866

Query: 3141 VD---KSKGQK-PRFTTHI--QNIEGLKDGQS----AHFECTVV--PVDDPDMKIEWYHN 3188
            +    + + Q   +  T +  QN    K G S    +    T+V   +  P   I W  N
Sbjct: 867  LGTYLRPQNQHCGKVITQLDHQNPVTSKVGASVTALSGVTVTLVCQAIGLPVPTITWTFN 926

Query: 3189 GQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYG 3243
            G+P+    ++ TV++    ++     ++ DSG+YVC A +  G+   R+ I   G
Sbjct: 927  GKPLTSHGQV-TVTNQSVTIIK---ARSEDSGDYVCNATSANGQGSARSVIKIEG 977



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704
           +V+A+ G  I      E  G P   + W K G +++   R          +  + S    
Sbjct: 256 NVSALRGSSITLTCTAE--GLPVPFVVWKKGGATLQQGGR----------AFTLSSTESA 303

Query: 705 DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEE 764
           DSG Y C A +  G A   + + +  +  IE+    P+ L   + L              
Sbjct: 304 DSGRYDCVATNLKGTAMASSAITIHDK--IEKRVA-PKILSSKKNLI------------- 347

Query: 765 QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824
            +  +  F   +     + EG++   E Q   +  P   V W+ +G  +T S  +    N
Sbjct: 348 ASENKRLFYHIIGGNITILEGKD--LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPN 405

Query: 825 FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            G  +L+I+ + AE+ G Y  ++ N  GE + T+
Sbjct: 406 TG--ALSIIEITAEEQGQYMCKSKNIAGEDLETS 437



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 44/211 (20%), Positives = 79/211 (37%), Gaps = 31/211 (14%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            D+ +       I ++ +L+   + K  C+   +G P   V W   G+P++  +R     +
Sbjct: 775  DQSKFSNLTVTIGTKVTLLASSSIKITCKA--IGIPKPVVTWTMRGRPVVPSDRVMVEKN 832

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIVYDSQLPKHMKSIEKI 4087
                A+ F  +   D+G  +C A N  G D   ++I   G     Y     +H   +  I
Sbjct: 833  ----ALVFLKILATDTGNVVCTANNARGSDVASSLITVLG----TYLRPQNQHCGKV--I 882

Query: 4088 REMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLN 4147
             +++                   PV   +  +VT   G      C+  G P P + W  N
Sbjct: 883  TQLDHQ----------------NPVTSKVGASVTALSGVTVTLVCQAIGLPVPTITWTFN 926

Query: 4148 GNTIVNGSRYKLTYDGMYHFDIPKTRQYDTG 4178
            G  + +  +  +T   +    I K R  D+G
Sbjct: 927  GKPLTSHGQVTVTNQSV---TIIKARSEDSG 954



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 4/98 (4%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            S  K  F   I   I+I EG     E +   IG     V W  +G  V  S  +    N 
Sbjct: 349  SENKRLFYHIIGGNITILEG--KDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNT 406

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            G  AL+I  +T  + G Y C++ N  G+   ++  T+V
Sbjct: 407  G--ALSIIEITAEEQGQYMCKSKNIAGEDLETSYTTVV 442



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 2/59 (3%)

Query: 942  RVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLT 1000
            +V W K+G P+ +  + T   +   V  + K+ +V D+G Y+CRA N +GQ T  + +T
Sbjct: 169  KVTWAKNG-PIASGDKFTIARSTDLVFNSGKA-SVFDSGRYSCRAVNNLGQDTAYSEVT 225



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 47/180 (26%), Positives = 72/180 (40%), Gaps = 28/180 (15%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHR-IR-TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            TG    +++W  N   +    R +R  V  +G+++      +   SG Y+C ATNK G A
Sbjct: 46   TGFPQPIVQWTRNKVDLTGRMRQLRYNVTHYGVIIDTRFNGEL--SGEYACLATNKGGFA 103

Query: 3133 EISVKLEC------------VDKS-------KGQKPRFTTHIQNIEGLKDGQSAHFECTV 3173
             ++  L+             V  S       K + P   T    +E L  G      C V
Sbjct: 104  AVTTDLQIKAPFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKVETLT-GTEVSIICPV 162

Query: 3174 VPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
              +  P  K+ W  NG P+    +  T++    +V +       DSG Y CRA N  G+D
Sbjct: 163  EGLPPP--KVTWAKNG-PIASGDKF-TIARSTDLVFNSGKASVFDSGRYSCRAVNNLGQD 218



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 6/72 (8%)

Query: 90  KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149
           K   K  G P PVV+WT +  P+V  ++  +  N      +L+  +I   D G   CTA 
Sbjct: 799 KITCKAIGIPKPVVTWTMRGRPVVPSDRVMVEKN------ALVFLKILATDTGNVVCTAN 852

Query: 150 NQYGEAICSVYI 161
           N  G  + S  I
Sbjct: 853 NARGSDVASSLI 864



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 2/55 (3%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718
           G P  K+ W KNG  I +  +FT I R   +  +    ++ DSG Y+CRAV+  G
Sbjct: 164 GLPPPKVTWAKNGP-IASGDKFT-IARSTDLVFNSGKASVFDSGRYSCRAVNNLG 216



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 8/115 (6%)

Query: 3945 QMEATIKKYTSEVYLTED-DLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPV-GD 4002
            Q++A  K +    ++T     + + K + P  VT      +L   E +     + PV G 
Sbjct: 110  QIKAPFKPFIRSTWVTGSVGTHKLLKSRDPVIVTIGDKVETLTGTEVSI----ICPVEGL 165

Query: 4003 PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMD 4057
            P  KV W  NG P+   ++FT       V  N G     DSG Y CRA N  G D
Sbjct: 166  PPPKVTWAKNG-PIASGDKFTIARSTDLV-FNSGKASVFDSGRYSCRAVNNLGQD 218



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 4/60 (6%)

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            I W  NG  LT+  ++  T      +++I   R++DSG Y C AT+  G+  + + IKIE
Sbjct: 921  ITWTFNGKPLTSHGQVTVTNQ----SVTIIKARSEDSGDYVCNATSANGQGSARSVIKIE 976



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 7/86 (8%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            Q PV ++   ++  +  G T    C+ I +  PT  + W  N K +    ++T T+    
Sbjct: 888  QNPVTSKVGASVTALS-GVTVTLVCQAIGLPVPT--ITWTFNGKPLTSHGQVTVTNQ--- 941

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLGE 2459
             S+TI   R ED G Y+C A++  G+
Sbjct: 942  -SVTIIKARSEDSGDYVCNATSANGQ 966



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 4/61 (6%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            + W  NGKPL +  +V T+ +    I++       D+G Y C AT+ +G+ +    ++++
Sbjct: 921  ITWTFNGKPLTSHGQV-TVTNQSVTIIK---ARSEDSGDYVCNATSANGQGSARSVIKIE 976

Query: 3651 G 3651
            G
Sbjct: 977  G 977



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 4096 VTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            +T    V E +++   + V++   VT+      +  C+  G PKP V W + G  +V   
Sbjct: 766  ITRSADVIEDQSKFSNLTVTIGTKVTLLASSSIKITCKAIGIPKPVVTWTMRGRPVVPSD 825

Query: 4156 RYKLTYDGMYHFDIPKTRQYDTGKI 4180
            R  +  + +    I  T   DTG +
Sbjct: 826  RVMVEKNALVFLKILAT---DTGNV 847



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 2/66 (3%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P+V WTR K  L       +RYN     V ++  +      GEY C A N+ G A 
Sbjct: 47  GFPQPIVQWTRNKVDLTG-RMRQLRYNVTHYGV-IIDTRFNGELSGEYACLATNKGGFAA 104

Query: 157 CSVYIQ 162
            +  +Q
Sbjct: 105 VTTDLQ 110



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 4/64 (6%)

Query: 3447 TDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVT 3506
            T  PN  + W  NG+S+  G   +     G  +L  +P   ED+G Y C A N  G+A  
Sbjct: 489  TGFPNPLIRWSRNGESVVPGGHLKID---GSKLLLTNPQ-KEDNGVYKCLASNPGGDATA 544

Query: 3507 TASM 3510
            T++M
Sbjct: 545  TSNM 548



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 17/63 (26%), Positives = 35/63 (55%), Gaps = 4/63 (6%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P   + W  +G+P+T+  ++T + N    S+ I+  R+ED+G Y   A +  G+  + + 
Sbjct: 917 PVPTITWTFNGKPLTSHGQVT-VTN---QSVTIIKARSEDSGDYVCNATSANGQGSARSV 972

Query: 860 IRV 862
           I++
Sbjct: 973 IKI 975



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 4115 SLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTR 4173
            S+ +A+T+ +G      C  TG P+P V W  N    + G   +L Y+  ++  I  TR
Sbjct: 26   SIGNAITLLKGSRVTLVCHATGFPQPIVQWTRN-KVDLTGRMRQLRYNVTHYGVIIDTR 83



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTSGS 2862
            P   I W  N + +  G   K   D S   L +T+  +ED+G+Y C A+N  G AT + +
Sbjct: 492  PNPLIRWSRNGESVVPGGHLKI--DGS--KLLLTNPQKEDNGVYKCLASNPGGDATATSN 547

Query: 2863 L 2863
            +
Sbjct: 548  M 548


>SB_29237| Best HMM Match : I-set (HMM E-Value=0)
          Length = 869

 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 83/285 (29%), Positives = 114/285 (40%), Gaps = 30/285 (10%)

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
            +G L++L  K  G   + V W K+G  + P   N  +   G   L        DSG Y C
Sbjct: 148  AGILIQLRCKCNGMPKVTVEWKKDGVTIIP---NSEIVASGN-RLNFENPKVADSGNYTC 203

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
            +A N  G        V   PA K         A+ P   + P  D I   G  I   C  
Sbjct: 204  IAQNFLG--------VRESPAFK----MSVIVASVPVFQVRP-SDTIAVVGDTITLYCSA 250

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G P P + WY            ++S  AD  +L+IS     D G YKCVA N      V
Sbjct: 251  TGTPKPDISWYLETSTDPLKNSSKISANADG-SLKISNIEKSDFGTYKCVASNIMANYAV 309

Query: 4707 AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW-LREGALIPETP 4765
             A++      +    P   P R I+  E QP  F   +    KPTI W L +G  +P   
Sbjct: 310  EAEVGEAFIGEMVLAP---PTRYIL--EKQPFTFACDVKGLPKPTISWSLADGKSLPAKY 364

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            D +     NN       T  ED+G FTC A+  AG+   + ++++
Sbjct: 365  DMKGTALRNN------KTAMEDSGNFTCTASNTAGKKSQTVQIII 403



 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 82/329 (24%), Positives = 137/329 (41%), Gaps = 54/329 (16%)

Query: 250 VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF--KNGQRLI 307
           V+ S     S+   S P    +P ++    G         +G P+P ++W+   +   L 
Sbjct: 211 VRESPAFKMSVIVASVPVFQVRPSDTIAVVGDTITLYCSATGTPKPDISWYLETSTDPLK 270

Query: 308 NSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQR 367
           NS+K   I+ +   +L++ N +KSD G Y  +A N     + + Y AVE+          
Sbjct: 271 NSSK---ISANADGSLKISNIEKSDFGTYKCVASN-----IMANY-AVEA---------- 311

Query: 368 SQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFI 427
                     E  E   I E  LAP        R + E +   F C V G P P ++W +
Sbjct: 312 ----------EVGEAF-IGEMVLAPP------TRYILEKQPFTFACDVKGLPKPTISWSL 354

Query: 428 ND-RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKE 486
            D + +   Y+ K         AL      + DSG  TC A N +G+ +   ++ + +  
Sbjct: 355 ADGKSLPAKYDMK-------GTALRNNKTAMEDSGNFTCTASNTAGKKSQTVQIIISQP- 406

Query: 487 QVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
               P   E    +   EG  VVL   A G P P++ WQ++ + ++ +    I++ G   
Sbjct: 407 ----PVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKLIWQRNQIDVVQDGNHEINSRG--- 459

Query: 547 TLDIPRAKASDAAWYQCTAQNVAGSTATR 575
            L I +    D   Y+C A+++ G  AT+
Sbjct: 460 YLVIRKVAPRDGGLYECIARHLGGWEATK 488



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 70/288 (24%), Positives = 109/288 (37%), Gaps = 32/288 (11%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P F +   +     G  + L    TGT   D+ W        P   +  +  +   +L I
Sbjct: 227  PVFQVRPSDTIAVVGDTITLYCSATGTPKPDISWYLE-TSTDPLKNSSKISANADGSLKI 285

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
                  D G Y+CVA N       +AE   +            +   APP        + 
Sbjct: 286  SNIEKSDFGTYKCVASNIMANYAVEAEVGEAFIG---------EMVLAPPT-------RY 329

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            + E Q   F+C + G P PT+ W   D    P+KY  M  TA    LR ++   ED G++
Sbjct: 330  ILEKQPFTFACDVKGLPKPTISWSLADGKSLPAKY-DMKGTA----LRNNKTAMEDSGNF 384

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTI 4752
             C A N+AG+ +   ++ ++QP      P LT   +D+   EG     K        P +
Sbjct: 385  TCTASNTAGKKSQTVQIIISQP------PVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKL 438

Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             W R    + +  + ++   G    L+I      D G + C A    G
Sbjct: 439  IWQRNQIDVVQDGNHEINSRG---YLVIRKVAPRDGGLYECIARHLGG 483



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 76/297 (25%), Positives = 113/297 (38%), Gaps = 23/297 (7%)

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVT-GTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            +F    Q+  V  GQ V L      G + I   W  +G K++P  R  I+ +DG+  L I
Sbjct: 37   TFLAQPQDTAVVLGQAVTLKCVAQFGDRRIRYSWTLDGNKIRPTDR-VIVNQDGS--LSI 93

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
            +    +D+G+Y CVA  +    R   E   +            K A++P + + P     
Sbjct: 94   IATQKEDAGEYICVA-KARMNKRNYVESSRAAALEVQSICEAAKIASSPSQSLFP----- 147

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
               G  I+  CK  G P  TV+W K    I P+        A    L        D G+Y
Sbjct: 148  --AGILIQLRCKCNGMPKVTVEWKKDGVTIIPNSEI----VASGNRLNFENPKVADSGNY 201

Query: 4694 KCVAYNSAG-RVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQITSKIKPT 4751
             C+A N  G R + A K+ V       ++P       D +   G         T   KP 
Sbjct: 202  TCIAQNFLGVRESPAFKMSVI----VASVPVFQVRPSDTIAVVGDTITLYCSATGTPKPD 257

Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            I W  E +  P   +   I    +  L I N  + D GT+ C A+         A++
Sbjct: 258  ISWYLETSTDP-LKNSSKISANADGSLKISNIEKSDFGTYKCVASNIMANYAVEAEV 313



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 86/350 (24%), Positives = 139/350 (39%), Gaps = 49/350 (14%)

Query: 4377 EITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDG 4436
            E +   T T +     K+QT + ++      S+PP+ T++ +  +  E  +   +    G
Sbjct: 379  EDSGNFTCTASNTAGKKSQTVQIII------SQPPVLTEEPKDMQAMEGLKVVLKCAAKG 432

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGG-TAKCS 4495
             P P + W R    +    +   H  +++  L+IR+V   D  ++  +A + GG  A  +
Sbjct: 433  VPPPKLIWQRNQIDVVQDGN---HEINSRGYLVIRKVAPRDGGLYECIARHLGGWEATKT 489

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            AN+ V    +      V   F L         G   ++     G  P+ + W K G    
Sbjct: 490  ANVSVMAAVKLADYHQVHHKFDL---------GSKGKIYCTFKGHPPVKIVWAKVGGAE- 539

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
                +K  E DG  TL+I +    D+G Y C  +N  G +   A   VS+      PK +
Sbjct: 540  ---LSKKTEIDGD-TLIIKDLQMSDAGMYSCTGMN--GFSNYTAYVNVSVFV---YPKFE 590

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK----GDKLIKPSKYFQM 4671
             K  N     ++           +I   C   G P P + W K    GD L K  ++ Q 
Sbjct: 591  LKPKNTTAMAMD-----------SIWLHCNASGYPKPKISWGKEQQGGDNLDK-ERFIQF 638

Query: 4672 SRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
                +  +L I     EDEG Y C+A N A    +   LKV +   A+ L
Sbjct: 639  ----ENGSLLIKNIKLEDEGRYYCIAGNLADFKQITISLKVVRNSPAEAL 684



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 47/181 (25%), Positives = 78/181 (43%), Gaps = 12/181 (6%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVT-GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
           F+   QD  V  G+     C    G      +W ++  +IR     +++VN+ G+ +++ 
Sbjct: 38  FLAQPQDTAVVLGQAVTLKCVAQFGDRRIRYSWTLDGNKIRP--TDRVIVNQDGSLSIIA 95

Query: 453 TNVTLSDSGVVTCVARNKSGETAF--QCRLNVIEKEQVV-APKFVERFSTLNVREGEPVV 509
           T     D+G   CVA+ +  +  +    R   +E + +  A K     S      G  + 
Sbjct: 96  TQK--EDAGEYICVAKARMNKRNYVESSRAAALEVQSICEAAKIASSPSQSLFPAGILIQ 153

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L  +  G P   + W+KDGV IIPN E+        + L+    K +D+  Y C AQN  
Sbjct: 154 LRCKCNGMPKVTVEWKKDGVTIIPNSEI----VASGNRLNFENPKVADSGNYTCIAQNFL 209

Query: 570 G 570
           G
Sbjct: 210 G 210



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 48/191 (25%), Positives = 71/191 (37%), Gaps = 14/191 (7%)

Query: 389 ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           A  P F     D     G      C  TG P P+++W++         + KI  N  G  
Sbjct: 224 ASVPVFQVRPSDTIAVVGDTITLYCSATGTPKPDISWYLETSTDPLKNSSKISANADG-- 281

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRL-NVIEKEQVVAPKFVERFSTLNVREGEP 507
           +L I+N+  SD G   CVA N     A +  +      E V+AP       T  + E +P
Sbjct: 282 SLKISNIEKSDFGTYKCVASNIMANYAVEAEVGEAFIGEMVLAP------PTRYILEKQP 335

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
                   G P P I+W      +     L    D   + L   +    D+  + CTA N
Sbjct: 336 FTFACDVKGLPKPTISWS-----LADGKSLPAKYDMKGTALRNNKTAMEDSGNFTCTASN 390

Query: 568 VAGSTATRARL 578
            AG  +   ++
Sbjct: 391 TAGKKSQTVQI 401



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 49/176 (27%), Positives = 68/176 (38%), Gaps = 12/176 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P   +  +D    EG      C   G P P++ W  N   +  D NH+I  N  G   L+
Sbjct: 407 PVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKLIWQRNQIDVVQDGNHEI--NSRGY--LV 462

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           I  V   D G+  C+AR+  G  A +   NV     V    + +     ++  G    + 
Sbjct: 463 IRKVAPRDGGLYECIARHLGGWEATKTA-NVSVMAAVKLADYHQVHHKFDL--GSKGKIY 519

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
               G P  +I W K G       EL   T+    TL I   + SDA  Y CT  N
Sbjct: 520 CTFKGHPPVKIVWAKVG-----GAELSKKTEIDGDTLIIKDLQMSDAGMYSCTGMN 570



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 55/274 (20%), Positives = 105/274 (38%), Gaps = 19/274 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+  +  K+ +  +G     +   +G P P + W R +  +V+   + +          
Sbjct: 406 PPVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKLIWQRNQIDVVQDGNHEINSRGY----- 460

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
           L+I+++ P D G Y C AR+  G      +   +              Y  V    +  +
Sbjct: 461 LVIRKVAPRDGGLYECIARHLGG------WEATKTANVSVMAAVKLADYHQVHHKFDLGS 514

Query: 191 YGTQGYTTEQSRQTQKVAYTN--GTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES 248
            G + Y T +     K+ +    G + S   +   DT    +++++   ++      G +
Sbjct: 515 KG-KIYCTFKGHPPVKIVWAKVGGAELSKKTEIDGDTL---IIKDLQMSDAGMYSCTGMN 570

Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
                T    ++     PK   KP+N+              SG P+P+++W K  Q   N
Sbjct: 571 GFSNYTAYV-NVSVFVYPKFELKPKNTTAMAMDSIWLHCNASGYPKPKISWGKEQQGGDN 629

Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            +K   I   N + L ++N +  D G Y  +A N
Sbjct: 630 LDKERFIQFENGSLL-IKNIKLEDEGRYYCIAGN 662



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 267 KIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVR 326
           KIA  P  S    G   Q + + +G P+  V W K+G  +I ++  EI+ + N   L   
Sbjct: 136 KIASSPSQSLFPAGILIQLRCKCNGMPKVTVEWKKDGVTIIPNS--EIVASGNR--LNFE 191

Query: 327 NTQKSDSGHYTLLAEN 342
           N + +DSG+YT +A+N
Sbjct: 192 NPKVADSGNYTCIAQN 207



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 10/128 (7%)

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
           E     L+I ++ +SD+G+ +C   N  G + +   +NV      V PKF  +       
Sbjct: 545 EIDGDTLIIKDLQMSDAGMYSCTGMN--GFSNYTAYVNV---SVFVYPKFELKPKNTTAM 599

Query: 504 EGEPVVLNARAVGTPTPRITWQKD--GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
             + + L+  A G P P+I+W K+  G   + + E  I  + G  +L I   K  D   Y
Sbjct: 600 AMDSIWLHCNASGYPKPKISWGKEQQGGDNL-DKERFIQFENG--SLLIKNIKLEDEGRY 656

Query: 562 QCTAQNVA 569
            C A N+A
Sbjct: 657 YCIAGNLA 664



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            +I+Q PV T   KD++  E      +     V  PKL   W RN + +        ++  
Sbjct: 402  IISQPPVLTEEPKDMQAMEGLKVVLKCAAKGVPPPKL--IWQRNQIDVVQDGN-HEINSR 458

Query: 1766 GYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHE 1815
            GY+ +  + V P D G Y C A   LG    + T  V   A+++L   H+
Sbjct: 459  GYLVI--RKVAPRDGGLYECIA-RHLGGWEATKTANVSVMAAVKLADYHQ 505



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 16/156 (10%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI- 3134
            G   + +EW  +G TI  +  I    A G   L     K  DSG Y+C A N  G  E  
Sbjct: 160  GMPKVTVEWKKDGVTIIPNSEI---VASGNR-LNFENPKVADSGNYTCIAQNFLGVRESP 215

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWY--HNGQPM 3192
            + K+  +  S    P F     +   +  G +    C+      PD  I WY   +  P+
Sbjct: 216  AFKMSVIVAS---VPVFQVRPSDTIAVV-GDTITLYCSATGTPKPD--ISWYLETSTDPL 269

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
            ++S++I   +D     L I+  +  D G Y C A N
Sbjct: 270  KNSSKISANADGS---LKISNIEKSDFGTYKCVASN 302



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 4/55 (7%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            G PK+ VEW ++GV I  ++ +    +     LN +     DSG YTC A N LG
Sbjct: 160  GMPKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIAQNFLG 210



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 4/59 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P + +EW K+GVT+   + + ++ +     L+  + +  DSG YTC A N LG   S A
Sbjct: 162  PKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIAQNFLGVRESPA 216



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 2/78 (2%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  +G P P+++W   ++Q  D+ + +  + +  N +L+I N+ L D G   C+A N + 
Sbjct: 608 CNASGYPKPKISWG-KEQQGGDNLDKERFI-QFENGSLLIKNIKLEDEGRYYCIAGNLAD 665

Query: 473 ETAFQCRLNVIEKEQVVA 490
                  L V+      A
Sbjct: 666 FKQITISLKVVRNSPAEA 683



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 23/59 (38%), Positives = 30/59 (50%), Gaps = 4/59 (6%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
           P + VEW KDG  I  +S I +  N     LN  + +  D+G+YT  A N LG   S A
Sbjct: 162 PKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIAQNFLGVRESPA 216



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/100 (29%), Positives = 41/100 (41%), Gaps = 7/100 (7%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            E  P  F C V+ +  PT  I W       A G  +    D    AL  +     D+G +
Sbjct: 332  EKQPFTFACDVKGLPKPT--ISW-----SLADGKSLPAKYDMKGTALRNNKTAMEDSGNF 384

Query: 3769 TCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKI 3808
            TC A+N  G  + T +I  S    +  E +  Q M G K+
Sbjct: 385  TCTASNTAGKKSQTVQIIISQPPVLTEEPKDMQAMEGLKV 424



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 6/86 (6%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYT 1918
            GQ+   +C +  + D  +R  W  +G  ++   R   + D    +L I+    ED+GEY 
Sbjct: 50   GQAVTLKC-VAQFGDRRIRYSWTLDGNKIRPTDRVIVNQD---GSLSIIATQKEDAGEYI 105

Query: 1919 C--KAINNLGQAVSSIRLNVQSKESI 1942
            C  KA  N    V S R      +SI
Sbjct: 106  CVAKARMNKRNYVESSRAAALEVQSI 131



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 654 IHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRA 713
           I  + R +  G P + +EW K+G +I  +S   +        L+  +  + DSG YTC A
Sbjct: 150 ILIQLRCKCNGMPKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIA 205

Query: 714 VSATGVAETKA 724
            +  GV E+ A
Sbjct: 206 QNFLGVRESPA 216



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 4/55 (7%)

Query: 937 GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
           G   + VEW KDG  +  +S I    N     L  ++  V D+G+YTC A N +G
Sbjct: 160 GMPKVTVEWKKDGVTIIPNSEIVASGN----RLNFENPKVADSGNYTCIAQNFLG 210



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 2/55 (3%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNT--IVNGSRYKLTYDG 4163
            PVF   P       G+     C  TG PKP + W L  +T  + N S+     DG
Sbjct: 227  PVFQVRPSDTIAVVGDTITLYCSATGTPKPDISWYLETSTDPLKNSSKISANADG 281



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            GQ+   +C V    D  ++  W  +G  +R + R+    D     L I  TQ  D+GEY+
Sbjct: 50   GQAVTLKC-VAQFGDRRIRYSWTLDGNKIRPTDRVIVNQDGS---LSIIATQKEDAGEYI 105

Query: 3224 CRA 3226
            C A
Sbjct: 106  CVA 108



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 5/90 (5%)

Query: 3276 TPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFH 3335
            T S     F+ Q QD T +V GQ+   +  +    D  ++  W  +G K+    R     
Sbjct: 30   TESQSKITFLAQPQD-TAVVLGQAVTLKC-VAQFGDRRIRYSWTLDGNKIRPTDRVIVNQ 87

Query: 3336 DFGIVILDILYCYEENSGEYECVATNKLGR 3365
            D     L I+   +E++GEY CVA  ++ +
Sbjct: 88   DGS---LSIIATQKEDAGEYICVAKARMNK 114



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/122 (23%), Positives = 49/122 (40%), Gaps = 8/122 (6%)

Query: 1836 VEVAVNQAPRFITQLNGPTK-LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYR 1894
            VE  V +A      L  PT+ + E Q   + C ++  P P   + W      L  G    
Sbjct: 309  VEAEVGEAFIGEMVLAPPTRYILEKQPFTFACDVKGLPKPT--ISWS-----LADGKSLP 361

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
               D    AL       EDSG +TC A N  G+   ++++ +     +  + +   A+E 
Sbjct: 362  AKYDMKGTALRNNKTAMEDSGNFTCTASNTAGKKSQTVQIIISQPPVLTEEPKDMQAMEG 421

Query: 1955 IQ 1956
            ++
Sbjct: 422  LK 423



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 7/95 (7%)

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852
            F C+V+    PT  I W      L  G    + +D    +L    T  EDSG +TC A+N
Sbjct: 338  FACDVKGLPKPT--ISW-----SLADGKSLPAKYDMKGTALRNNKTAMEDSGNFTCTASN 390

Query: 2853 SKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAV 2887
            + G  + +  +  +    +  + +  Q   GL+ V
Sbjct: 391  TAGKKSQTVQIIISQPPVLTEEPKDMQAMEGLKVV 425



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 4/69 (5%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G     +C V    D  +   W  +G KIR   R     D    +L I+ T  ED+G Y+
Sbjct: 50   GQAVTLKC-VAQFGDRRIRYSWTLDGNKIRPTDRVIVNQDG---SLSIIATQKEDAGEYI 105

Query: 2184 CKATNKLGE 2192
            C A  ++ +
Sbjct: 106  CVAKARMNK 114



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 17/51 (33%), Positives = 24/51 (47%)

Query: 2684 TLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +L  G  L + +D     L  N    +DSG +TC A+N  G+   T  I I
Sbjct: 353  SLADGKSLPAKYDMKGTALRNNKTAMEDSGNFTCTASNTAGKKSQTVQIII 403


>SB_1528| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2409

 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 83/306 (27%), Positives = 125/306 (40%), Gaps = 29/306 (9%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN----KILEEDGTY 4569
            P  TL   ++  +  Q   L  + TG+    +YWLK+G+ V  D  +    + +  +G  
Sbjct: 792  PVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDL 851

Query: 4570 TLL--ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            T L  I +    DSG Y+CVA NSAG+A        S  AT +    ++K    P     
Sbjct: 852  TFLRVINKKRKSDSGVYQCVAENSAGKA-------FSKNATLEVGVLRSKFRAEP----- 899

Query: 4628 PLKDKIVAEGQAIEFSCKIV-GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
              KD  +  G      C    G+P PTV W K  K   P       +      L IS A 
Sbjct: 900  --KDLSITIGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDGV--RIQKVSPGNLVISIAQ 955

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
              D G Y+CVA N+ GR   +    VT  +      ++ P + I V  GQ   F  Q   
Sbjct: 956  KADMGTYQCVAANAVGR-RKSRVATVTIKESPTTALSIDP-KQITVISGQSTSFSCQYRD 1013

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSA 4806
              +  ++W ++G  +P            +  L + +    D G + C     +G +  SA
Sbjct: 1014 GPQAAVRWQKKGGDLP----LNRYVTTQSGELQLSSIQPGDAGEYVCSVPLESGVLSVSA 1069

Query: 4807 KLVVKS 4812
            KL V++
Sbjct: 1070 KLEVQN 1075



 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 76/284 (26%), Positives = 118/284 (41%), Gaps = 34/284 (11%)

Query: 4436 GEPLPLIKWYRENFPIK-NSPDFQIHTFSTKS-----ILIIRQVFVEDSAVFAAVAENRG 4489
            G P P I W ++   +  +  D +   F   +     + +I +    DS V+  VAEN  
Sbjct: 817  GSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSA 876

Query: 4490 GTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID-VYWL 4548
            G A  S N  +E        G++   F    +++++T G    L       +P   V WL
Sbjct: 877  GKA-FSKNATLEV-------GVLRSKFRAEPKDLSITIGNRAILKCNPPKGRPAPTVTWL 928

Query: 4549 KNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPAT 4608
            KN K   PD     +++     L+I  A   D G Y+CVA N+ G  +     V      
Sbjct: 929  KNTKAYVPD--GVRIQKVSPGNLVISIAQKADMGTYQCVAANAVGRRKSRVATVTI---- 982

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKY 4668
              K  P T  +  P +I        V  GQ+  FSC+    P   V+W K    +  ++Y
Sbjct: 983  --KESPTTALSIDPKQIT-------VISGQSTSFSCQYRDGPQAAVRWQKKGGDLPLNRY 1033

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 T     L++S   P D G+Y C     +G ++V+AKL+V
Sbjct: 1034 V----TTQSGELQLSSIQPGDAGEYVCSVPLESGVLSVSAKLEV 1073



 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 11/173 (6%)

Query: 409 TRFDCRVTGRPYPEVTWFINDRQI----RDDYNHK-ILVNESGNHALMITNVTLSDSGVV 463
           T   CR TG P P++ W  + R +     D  N + I+ N       +I     SDSGV 
Sbjct: 809 TDLRCRATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVY 868

Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR-AVGTPTPRI 522
            CVA N +G+ AF    N   +  V+  KF      L++  G   +L      G P P +
Sbjct: 869 QCVAENSAGK-AFS--KNATLEVGVLRSKFRAEPKDLSITIGNRAILKCNPPKGRPAPTV 925

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           TW K+    +P+  +RI        L I  A+ +D   YQC A N  G   +R
Sbjct: 926 TWLKNTKAYVPD-GVRIQ-KVSPGNLVISIAQKADMGTYQCVAANAVGRRKSR 976



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 48/190 (25%), Positives = 79/190 (41%), Gaps = 14/190 (7%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLI------KPSKYFQMSR 4673
            N  P I     D + +  Q  +  C+  G P P + W K  +++        ++ F M  
Sbjct: 789  NTKPVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPN 848

Query: 4674 TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY 4733
                +   I++    D G Y+CVA NSAG+    +K    +     +     P +D+ + 
Sbjct: 849  GDLTFLRVINKKRKSDSGVYQCVAENSAGK--AFSKNATLEVGVLRSKFRAEP-KDLSIT 905

Query: 4734 EGQPAQFK-TQITSKIKPTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
             G  A  K      +  PT+ WL+   A +P+    Q +  GN   L+I    + D GT+
Sbjct: 906  IGNRAILKCNPPKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGN---LVISIAQKADMGTY 962

Query: 4792 TCRATTAAGQ 4801
             C A  A G+
Sbjct: 963  QCVAANAVGR 972



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 9/110 (8%)

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
           ET FQ RL +   +    P      S +     +P  L  RA G+P P+I W KDG  I+
Sbjct: 775 ETCFQ-RLEIFGDDWNTKPVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDG-RIV 832

Query: 533 P----NPELR--IHTDGGASTLD-IPRAKASDAAWYQCTAQNVAGSTATR 575
           P    + E R  I  +G  + L  I + + SD+  YQC A+N AG   ++
Sbjct: 833 PTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSAGKAFSK 882



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 46/180 (25%), Positives = 70/180 (38%), Gaps = 15/180 (8%)

Query: 3074 PTGDQSMVIEWFYNGKT-IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            P G  +  + W  N K  +    RI+ V   G +V+ I   +  D GTY C A N  G+ 
Sbjct: 917  PKGRPAPTVTWLKNTKAYVPDGVRIQKVSP-GNLVISI--AQKADMGTYQCVAANAVGRR 973

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
            +  V    + +S    P     I   +  +  GQS  F C     D P   + W   G  
Sbjct: 974  KSRVATVTIKES----PTTALSIDPKQITVISGQSTSFSCQY--RDGPQAAVRWQKKGGD 1027

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251
            +  +  + T S      L ++  Q  D+GEYVC    + G     A +     G  ++ S
Sbjct: 1028 LPLNRYVTTQSG----ELQLSSIQPGDAGEYVCSVPLESGVLSVSAKLEVQNYGRFFVSS 1083



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 8/87 (9%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLI------NSNKHEIITTHN 319
           P I   P +           + + +G+P+P++ W K+G R++      + N+  I+   +
Sbjct: 792 PVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDG-RIVPTDGEDSENRRFIMPNGD 850

Query: 320 HTTLRVRN-TQKSDSGHYTLLAENPNG 345
            T LRV N  +KSDSG Y  +AEN  G
Sbjct: 851 LTFLRVINKKRKSDSGVYQCVAENSAG 877



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 68/293 (23%), Positives = 109/293 (37%), Gaps = 49/293 (16%)

Query: 291  GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
            G P P VTW KN +  +       I   +   L +   QK+D G Y  +A N  G     
Sbjct: 919  GRPAPTVTWLKNTKAYVPDGVR--IQKVSPGNLVISIAQKADMGTYQCVAANAVG----- 971

Query: 351  GYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410
                           ++S+  T T +      + I  K +            V  G+ T 
Sbjct: 972  --------------RRKSRVATVTIKESPTTALSIDPKQIT-----------VISGQSTS 1006

Query: 411  FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470
            F C+    P   V W    ++  D   ++ +  +SG   L ++++   D+G   C    +
Sbjct: 1007 FSCQYRDGPQAAVRW---QKKGGDLPLNRYVTTQSGE--LQLSSIQPGDAGEYVCSVPLE 1061

Query: 471  SGETAFQCRLNVIEKEQVVAPKFVE-RFSTLNVR-EGEPV--VLNARAVGTPTPR----- 521
            SG  +   +L V    +       E R S++    EGE V   L+   +G  + R     
Sbjct: 1062 SGVLSVSAKLEVQNYGRFFVSSNGELRISSVKKEDEGEYVCSALSPAGLGASSARAMLTV 1121

Query: 522  -ITWQK--DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             + W K  D + ++ N    I T G  + L I +    DA  Y+C   N  GS
Sbjct: 1122 WLQWIKRDDSMRVLRNSSRVIITTGTLARLRISQLTLGDAGEYRCVVSNQLGS 1174



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 54/210 (25%), Positives = 82/210 (39%), Gaps = 22/210 (10%)

Query: 1736 PVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P G P   V WL+N                G + +++      D GTY C A N +G   
Sbjct: 917  PKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNLVISI--AQKADMGTYQCVAANAVGRRK 974

Query: 1796 TS-STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVN------QAP--RF 1846
            +  +T+ ++   +  L S     +  I     S   Q R+  + AV         P  R+
Sbjct: 975  SRVATVTIKESPTTAL-SIDPKQITVISGQSTSFSCQYRDGPQAAVRWQKKGGDLPLNRY 1033

Query: 1847 ITQLNGPTKLSE---GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            +T  +G  +LS    G +  Y C + P     + V      +V   G  + +SN      
Sbjct: 1034 VTTQSGELQLSSIQPGDAGEYVCSV-PLESGVLSVSAKL--EVQNYGRFFVSSN----GE 1086

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIR 1933
            L I +V  ED GEY C A++  G   SS R
Sbjct: 1087 LRISSVKKEDEGEYVCSALSPAGLGASSAR 1116



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 96/452 (21%), Positives = 164/452 (36%), Gaps = 47/452 (10%)

Query: 97   GNPTPVVSWTR--KKAPLVECNKYSMRYNEQTGDVSLL--IKQIGPGDEGEYTCTARNQY 152
            G+P P + W +  +  P    +  + R+    GD++ L  I +    D G Y C A N  
Sbjct: 817  GSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSA 876

Query: 153  GEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNG 212
            G+A         G              + +S T+ ++A         + R    V +   
Sbjct: 877  GKAFSKNATLEVGVLRSKFRAEP----KDLSITIGNRAI--LKCNPPKGRPAPTVTWLKN 930

Query: 213  TDHSSTDDFKVDTFEYRLL-------REVSFRESITKRYVGESDVQISTEIDRSLGPVSP 265
            T     D  ++       L        ++   + +    VG    +++T   +   P + 
Sbjct: 931  TKAYVPDGVRIQKVSPGNLVISIAQKADMGTYQCVAANAVGRRKSRVATVTIKE-SPTTA 989

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
              I   P+   +  G    F  Q    P+  V W K G  L   N++  +TT +   L++
Sbjct: 990  LSI--DPKQITVISGQSTSFSCQYRDGPQAAVRWQKKGGDL-PLNRY--VTTQS-GELQL 1043

Query: 326  RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
             + Q  D+G Y       +G +  S  L V++    +V       I+  ++   E+  E 
Sbjct: 1044 SSIQPGDAGEYVCSVPLESGVLSVSAKLEVQNYGRFFVSSNGELRISSVKK---EDEGEY 1100

Query: 386  SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
               AL+P  +     R      +T +           + W   D  +R   N   ++  +
Sbjct: 1101 VCSALSPAGLGASSAR----AMLTVW-----------LQWIKRDDSMRVLRNSSRVIITT 1145

Query: 446  GNHA-LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVR 503
            G  A L I+ +TL D+G   CV  N+ G       L VI      A +  +  S T+++ 
Sbjct: 1146 GTLARLRISQLTLGDAGEYRCVVSNQLGSVFAASFLTVIGIADFQALRIAKIVSLTIDLP 1205

Query: 504  EGEPVVLNARAVGTPTPRITWQKDGVPIIPNP 535
             G P    AR V T     T  K     IP+P
Sbjct: 1206 VGIPT--TAR-VTTRRSTSTKPKTSSIFIPDP 1234



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 8/94 (8%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG--VPIE---ASNRLTTMHDF 1765
            PV T+   DI  + NQ      R    G PK ++ WL++G  VP +   + NR   M + 
Sbjct: 792  PVITLDPSDIVASRNQPTDLRCRA--TGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNG 849

Query: 1766 GYVALNM-KYVNPEDSGTYTCRAINELGEAVTSS 1798
                L +       DSG Y C A N  G+A + +
Sbjct: 850  DLTFLRVINKKRKSDSGVYQCVAENSAGKAFSKN 883



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 61/208 (29%), Positives = 85/208 (40%), Gaps = 23/208 (11%)

Query: 3042 DDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI----EASHRI 3097
            DD    P  T    DIV  S  Q          TG     I W  +G+ +    E S   
Sbjct: 786  DDWNTKPVITLDPSDIV-ASRNQPTDLRCRA--TGSPKPKIYWLKDGRIVPTDGEDSENR 842

Query: 3098 RTVYAFG-MVVLEILGTKT-TDSGTYSCRATNKWGQA-EISVKLEC-VDKSKGQKPRFTT 3153
            R +   G +  L ++  K  +DSG Y C A N  G+A   +  LE  V +SK     F  
Sbjct: 843  RFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSAGKAFSKNATLEVGVLRSK-----FRA 897

Query: 3154 HIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP-MRHSTRIKTVSDFGFVVLDIA 3212
              +++  +  G  A  +C   P   P   + W  N +  +    RI+ VS  G +V+ IA
Sbjct: 898  EPKDL-SITIGNRAILKCN-PPKGRPAPTVTWLKNTKAYVPDGVRIQKVSP-GNLVISIA 954

Query: 3213 YTQNHDSGEYVCRAYNKYGEDFTR-ATI 3239
              Q  D G Y C A N  G   +R AT+
Sbjct: 955  --QKADMGTYQCVAANAVGRRKSRVATV 980



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 6/75 (8%)

Query: 79   KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
            K      G +  F  + R  P   V W +K   L   N+Y      Q+G++ L    I P
Sbjct: 995  KQITVISGQSTSFSCQYRDGPQAAVRWQKKGGDL-PLNRY---VTTQSGELQL--SSIQP 1048

Query: 139  GDEGEYTCTARNQYG 153
            GD GEY C+   + G
Sbjct: 1049 GDAGEYVCSVPLESG 1063



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 56/232 (24%), Positives = 93/232 (40%), Gaps = 16/232 (6%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            + +F+   KD +SI  G  A  +    P G     V WLK+ +            + G +
Sbjct: 892  RSKFRAEPKD-LSITIGNRAILKCN-PPKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNL 949

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKI--QYLED 1025
             ++I      D G Y C A NA+G+  +      + +    A S  P  +  I  Q    
Sbjct: 950  VISIAQKA--DMGTYQCVAANAVGRRKSRVATVTIKESPTTALSIDPKQITVISGQSTSF 1007

Query: 1026 ASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFE-ARVEP--QSDLTMTVEWYFN 1082
            + +Y    +  V+  +K   L PL   N+ V  QS   + + ++P    +   +V     
Sbjct: 1008 SCQYRDGPQAAVRWQKKGGDL-PL---NRYVTTQSGELQLSSIQPGDAGEYVCSVPLESG 1063

Query: 1083 GKQITSANRIQTYHDFGYVA---LDIASVRAEDSGVYTVVARNAAGEAQLSA 1131
               +++   +Q Y  F   +   L I+SV+ ED G Y   A + AG    SA
Sbjct: 1064 VLSVSAKLEVQNYGRFFVSSNGELRISSVKKEDEGEYVCSALSPAGLGASSA 1115



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 12/130 (9%)

Query: 1838 VAVNQAPRFITQLNGPTKLS--EGQSAHYECRIEPYPD-PNMRVEWYFNGKVLQSGHRYR 1894
            V + ++P     ++ P +++   GQS  + C+   Y D P   V W   G  L   +RY 
Sbjct: 980  VTIKESPTTALSID-PKQITVISGQSTSFSCQ---YRDGPQAAVRWQKKGGDLPL-NRYV 1034

Query: 1895 TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
            T+       L + ++   D+GEY C      G    S +L VQ+       S  E  +  
Sbjct: 1035 TTQS---GELQLSSIQPGDAGEYVCSVPLESGVLSVSAKLEVQNYGRFFVSSNGELRISS 1091

Query: 1955 IQYLEDDSRY 1964
            ++  ED+  Y
Sbjct: 1092 VK-KEDEGEY 1100



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 13/41 (31%), Positives = 19/41 (46%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PV    P  +     +     CR TG PKP++ WL +G  +
Sbjct: 792  PVITLDPSDIVASRNQPTDLRCRATGSPKPKIYWLKDGRIV 832



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 8/108 (7%)

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRP-VQQGHRFKTTYDFG 2033
            V + +F    K+  +T G+   L+    P   P   V W  N +  V  G R +     G
Sbjct: 890  VLRSKFRAEPKDLSITIGNRAILKCN-PPKGRPAPTVTWLKNTKAYVPDGVRIQKVSP-G 947

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVG---EAVTTSSVKVDAKSGLYLD 2078
             + + I  A   D GTY C A NAVG     V T ++K    + L +D
Sbjct: 948  NLVISI--AQKADMGTYQCVAANAVGRRKSRVATVTIKESPTTALSID 993



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%)

Query: 657 ETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI------QDSGEYT 710
           + R    G P  KI WLK+G+ +      +   RF   + D+  L +       DSG Y 
Sbjct: 810 DLRCRATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQ 869

Query: 711 CRAVSATGVAETK-AVLHV 728
           C A ++ G A +K A L V
Sbjct: 870 CVAENSAGKAFSKNATLEV 888



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 17/120 (14%)

Query: 2356 LESAEPFK--RPEIPEPVTRQRPVF-----TQPLQNID--NIQEGQTAHFDCRLIPVGDP 2406
            +  AE FK  R  + E   ++  +F     T+P+  +D  +I   +    D R    G P
Sbjct: 760  ISQAERFKLRRESVCETCFQRLEIFGDDWNTKPVITLDPSDIVASRNQPTDLRCRATGSP 819

Query: 2407 TLKVEWFRNEKLI----EDSSR---ITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
              K+ W ++ +++    EDS     I    D  ++ + I+  R  D GVY C A N  G+
Sbjct: 820  KPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRV-INKKRKSDSGVYQCVAENSAGK 878



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 5/73 (6%)

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKL-IEDSSRITKTHDFGYVSMTISHVRDED 2445
            +I  G  A   C   P G P   V W +N K  + D  RI K      V   IS  +  D
Sbjct: 903  SITIGNRAILKCNP-PKGRPAPTVTWLKNTKAYVPDGVRIQKVSPGNLV---ISIAQKAD 958

Query: 2446 EGVYMCRASNLLG 2458
             G Y C A+N +G
Sbjct: 959  MGTYQCVAANAVG 971



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 6/63 (9%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDF----GLVTLS--INSLRNDDSGIYTCKATNLLGE 2725
            P  KI W K+G  + T         F    G +T    IN  R  DSG+Y C A N  G+
Sbjct: 819  PKPKIYWLKDGRIVPTDGEDSENRRFIMPNGDLTFLRVINKKRKSDSGVYQCVAENSAGK 878

Query: 2726 AVS 2728
            A S
Sbjct: 879  AFS 881



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 6/74 (8%)

Query: 940  TLRVEWLKDG---RPVEASSRITTFFNFGYVA-LTIKSVTVHDAGHYTCRAYNAIGQATT 995
            T+ ++W+K     R +  SSR+      G +A L I  +T+ DAG Y C   N +G    
Sbjct: 1120 TVWLQWIKRDDSMRVLRNSSRV--IITTGTLARLRISQLTLGDAGEYRCVVSNQLGSVFA 1177

Query: 996  SANLTIVTKKDIIA 1009
            ++ LT++   D  A
Sbjct: 1178 ASFLTVIGIADFQA 1191



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 10/91 (10%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSR-------VKTIN 3610
            P  T  PSD++ S N      CR         ++ W  +G+ + T          +    
Sbjct: 792  PVITLDPSDIVASRNQPTDLRCR--ATGSPKPKIYWLKDGRIVPTDGEDSENRRFIMPNG 849

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEA 3641
            D  F+ + I    + D+G+Y C A N  G+A
Sbjct: 850  DLTFLRV-INKKRKSDSGVYQCVAENSAGKA 879


>SB_8553| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 982

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 80/311 (25%), Positives = 127/311 (40%), Gaps = 40/311 (12%)

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
            TS + + LD K   T   D  W K+GKK+     +++  +   Y L I     +DSG+Y 
Sbjct: 68   TSREALVLDQKDVFT---DYIWYKDGKKMSVSHSSRMRIKRLRY-LKIKNLDKEDSGRYT 123

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCK 4645
            CVA    GE   +    V  P T    K + +       I  P+       G +++  C 
Sbjct: 124  CVAKRPCGEISANITLTVDSPPTFTVSKLKREKTL----IAMPV-------GNSLKLDCS 172

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
              GKP PTV W K  K        ++S    +Y L + +A P D+G Y C   N+ G + 
Sbjct: 173  ADGKPRPTVVWLKNGKPFLKRDGVELSLRPYQYVLSMRDAVPSDDGRYTCNVSNALGWIN 232

Query: 4706 VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR------EGA 4759
                + V +  +A   P L P+ ++ V  G+ A  + +  S   P  QW+R       G+
Sbjct: 233  HTYTVDVRERVRAK--PVLQPIANVTVLSGENATLECKAMSDSMPHFQWIRWFTARVNGS 290

Query: 4760 LIPETPDFQMIHEG-----------------NNAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
                T  F+++ +                  +   L + N  +ED G +TC    A G  
Sbjct: 291  SNETTLRFEVVKQTPHSDHILRPKSEHRFAFHGVKLTLFNVSKEDEGKYTCLVGNAVGYN 350

Query: 4803 ETSAKLVVKSK 4813
              +  L+VK +
Sbjct: 351  AENGYLIVKDQ 361



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 34/151 (22%), Positives = 60/151 (39%), Gaps = 2/151 (1%)

Query: 420 YPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCR 479
           + +  W+ + +++   ++ ++ +       L I N+   DSG  TCVA+   GE +    
Sbjct: 81  FTDYIWYKDGKKMSVSHSSRMRIKRL--RYLKIKNLDKEDSGRYTCVAKRPCGEISANIT 138

Query: 480 LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539
           L V         K     + + +  G  + L+  A G P P + W K+G P +    + +
Sbjct: 139 LTVDSPPTFTVSKLKREKTLIAMPVGNSLKLDCSADGKPRPTVVWLKNGKPFLKRDGVEL 198

Query: 540 HTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                   L +  A  SD   Y C   N  G
Sbjct: 199 SLRPYQYVLSMRDAVPSDDGRYTCNVSNALG 229



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 82/332 (24%), Positives = 127/332 (38%), Gaps = 57/332 (17%)

Query: 1064 EARVEPQSDLTMTVEWYFNGKQIT-SANRIQTYHDFGYVALDIASVRAEDSGVYTVVARN 1122
            EA V  Q D+     WY +GK+++ S +         Y  L I ++  EDSG YT VA+ 
Sbjct: 71   EALVLDQKDVFTDYIWYKDGKKMSVSHSSRMRIKRLRY--LKIKNLDKEDSGRYTCVAKR 128

Query: 1123 AAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQP 1182
              GE   + ++TV++                           P + + ++ + K +   P
Sbjct: 129  PCGEISANITLTVDS--------------------------PPTFTVSKLKREKTLIAMP 162

Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242
            + N        ++ L+C  +  G P   V W  NG+        +         L +  A
Sbjct: 163  VGN--------SLKLDCSAD--GKPRPTVVWLKNGKPFLKRDGVELSLRPYQYVLSMRDA 212

Query: 1243 TSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLL--EDAARRTKQ 1300
              +D G YT    N LG  + +  V V ER   V      Q I  + +L  E+A    K 
Sbjct: 213  VPSDDGRYTCNVSNALGWINHTYTVDVRER---VRAKPVLQPIANVTVLSGENATLECKA 269

Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
            + + +   Q  ++  A  N  + E T      +  P  D  +R          K+ HRF 
Sbjct: 270  MSDSMPHFQWIRWFTARVNGSSNETTLRFEVVKQTPHSDHILRP---------KSEHRFA 320

Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
                F  V L L +V  ED G YTC   N +G
Sbjct: 321  ----FHGVKLTLFNVSKEDEGKYTCLVGNAVG 348



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 1/108 (0%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW 299
           + KR  GE    I+  +D S    +  K+ ++     +  G   +      G PRP V W
Sbjct: 125 VAKRPCGEISANITLTVD-SPPTFTVSKLKREKTLIAMPVGNSLKLDCSADGKPRPTVVW 183

Query: 300 FKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
            KNG+  +  +  E+        L +R+   SD G YT    N  G I
Sbjct: 184 LKNGKPFLKRDGVELSLRPYQYVLSMRDAVPSDDGRYTCNVSNALGWI 231



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 58/221 (26%), Positives = 89/221 (40%), Gaps = 30/221 (13%)

Query: 1738 GDPKLRVEWLRNGVP-IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P+  V WL+NG P ++      ++  + YV L+M+   P D G YTC   N LG    
Sbjct: 175  GKPRPTVVWLKNGKPFLKRDGVELSLRPYQYV-LSMRDAVPSDDGRYTCNVSNALGWINH 233

Query: 1797 SSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856
            + T+ V+ +       + +  LQ I  +   S      + +   +  P F   +   T  
Sbjct: 234  TYTVDVRERV------RAKPVLQPIANVTVLSGENATLECKAMSDSMPHF-QWIRWFTAR 286

Query: 1857 SEGQSAHYECRIE-----PYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYG 1911
              G S     R E     P+ D  +R          +S HR+     F    L +  V  
Sbjct: 287  VNGSSNETTLRFEVVKQTPHSDHILRP---------KSEHRFA----FHGVKLTLFNVSK 333

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ---SKESIIRDSQHE 1949
            ED G+YTC   N +G    +  L V+   S  S + D+Q E
Sbjct: 334  EDEGKYTCLVGNAVGYNAENGYLIVKDQFSTTSTVIDTQAE 374



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/119 (23%), Positives = 47/119 (39%), Gaps = 3/119 (2%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G   + DC   G+P P V W  N +        ++ +     + L + +   SD G  TC
Sbjct: 164 GNSLKLDCSADGKPRPTVVWLKNGKPFLKRDGVELSLRPY-QYVLSMRDAVPSDDGRYTC 222

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
              N  G       ++V  +E+V A   ++  + + V  GE   L  +A+    P   W
Sbjct: 223 NVSNALGWINHTYTVDV--RERVRAKPVLQPIANVTVLSGENATLECKAMSDSMPHFQW 279



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 59/227 (25%), Positives = 89/227 (39%), Gaps = 29/227 (12%)

Query: 3693 NPPRFTVEI----KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH-TL 3747
            +PP FTV      K  I +P G  +  DC  +  G P   + W  NG+PF     V  +L
Sbjct: 143  SPPTFTVSKLKREKTLIAMPVGNSLKLDCSAD--GKPRPTVVWLKNGKPFLKRDGVELSL 200

Query: 3748 NDFGFIALDIDYIYARDAGEYTCRATNK--WGSATTTAKITCSAKRDIVLESQLPQGMSG 3805
              + ++ L +      D G YTC  +N   W + T T  +    +   VL+      +  
Sbjct: 201  RPYQYV-LSMRDAVPSDDGRYTCNVSNALGWINHTYTVDVRERVRAKPVLQPIANVTVLS 259

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFE-CRVEPKEDPKLRIE 3864
             +   LE   +SD+    P       F  ++   + E +  +RFE  +  P  D  LR +
Sbjct: 260  GENATLECKAMSDS---MPHFQWIRWFTARVNGSSNETT--LRFEVVKQTPHSDHILRPK 314

Query: 3865 WYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                     S HR+        V L +  V  ED G+Y C   N  G
Sbjct: 315  ---------SEHRFA----FHGVKLTLFNVSKEDEGKYTCLVGNAVG 348



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 34/148 (22%), Positives = 54/148 (36%), Gaps = 4/148 (2%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W+ +GK +  SH  R +    +  L+I      DSG Y+C A    G+   ++ L  VD 
Sbjct: 86   WYKDGKKMSVSHSSR-MRIKRLRYLKIKNLDKEDSGRYTCVAKRPCGEISANITL-TVDS 143

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
                        + +  +  G S   +C+      P   + W  NG+P      ++    
Sbjct: 144  PPTFTVSKLKREKTLIAMPVGNSLKLDCSA--DGKPRPTVVWLKNGKPFLKRDGVELSLR 201

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
                VL +      D G Y C   N  G
Sbjct: 202  PYQYVLSMRDAVPSDDGRYTCNVSNALG 229



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)

Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           W+K+G+++  S+   +        L+++N  K DSG YT +A+ P G I  +  L V+SP
Sbjct: 86  WYKDGKKMSVSHSSRM-RIKRLRYLKIKNLDKEDSGRYTCVAKRPCGEISANITLTVDSP 144



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 8/89 (8%)

Query: 3972 PPRF-VTQIQSQTSLVEM---ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRF-TPIY 4026
            PP F V++++ + +L+ M    + K +C     G P   V W  NGKP L ++     + 
Sbjct: 144  PPTFTVSKLKREKTLIAMPVGNSLKLDCSAD--GKPRPTVVWLKNGKPFLKRDGVELSLR 201

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
             + YV ++     P D G Y C  +N  G
Sbjct: 202  PYQYV-LSMRDAVPSDDGRYTCNVSNALG 229



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 17/68 (25%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G + K +    G P P V W +   P ++  +  +  + +     L ++   P D+G YT
Sbjct: 164 GNSLKLDCSADGKPRPTVVWLKNGKPFLK--RDGVELSLRPYQYVLSMRDAVPSDDGRYT 221

Query: 146 CTARNQYG 153
           C   N  G
Sbjct: 222 CNVSNALG 229



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 3/65 (4%)

Query: 806 WYKDGRPITAS-SRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
           WYKDG+ ++ S S    I    Y  L I +L  ED+G YT  A    GE  +  ++ V +
Sbjct: 86  WYKDGKKMSVSHSSRMRIKRLRY--LKIKNLDKEDSGRYTCVAKRPCGEISANITLTVDS 143

Query: 865 RSTVT 869
             T T
Sbjct: 144 PPTFT 148



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
            WY +GK +   H  R         L I  +  EDSG YTC A    G+  ++I L V S
Sbjct: 86   WYKDGKKMSVSHSSRMRIK-RLRYLKIKNLDKEDSGRYTCVAKRPCGEISANITLTVDS 143



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 61/241 (25%), Positives = 88/241 (36%), Gaps = 22/241 (9%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLK--VEWFKNGQPVTIGHRFR-P 1495
            +V   P F       E  +    V    KL+   D   +  V W KNG+P          
Sbjct: 140  TVDSPPTFTVSKLKREKTLIAMPVGNSLKLDCSADGKPRPTVVWLKNGKPFLKRDGVELS 199

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQI 1555
            +  + YV L + D +  D G YTC   N +G    +  +  R   + VR+      +  +
Sbjct: 200  LRPYQYV-LSMRDAVPSDDGRYTCNVSNALGWINHTYTVDVR---ERVRAKPVLQPIANV 255

Query: 1556 QVLE-DRSKYHRTDMVDEVT-TQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEW 1613
             VL  + +      M D +   Q     T+  N    E        +  P SD       
Sbjct: 256  TVLSGENATLECKAMSDSMPHFQWIRWFTARVNGSSNETTLRFEVVKQTPHSD------- 308

Query: 1614 YHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
             H  +P KS  RF     F  V L + +   ED G YTC   NA+G    +G  IV  + 
Sbjct: 309  -HILRP-KSEHRFA----FHGVKLTLFNVSKEDEGKYTCLVGNAVGYNAENGYLIVKDQF 362

Query: 1674 S 1674
            S
Sbjct: 363  S 363



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 5/57 (8%)

Query: 1480 WFKNGQPVTIGHRFRP-IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            W+K+G+ +++ H  R  I    Y+ +  +D   EDSG YTC A    G  E+S  +T
Sbjct: 86   WYKDGKKMSVSHSSRMRIKRLRYLKIKNLD--KEDSGRYTCVAKRPCG--EISANIT 138



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 2/102 (1%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTD--PNLKIEWFKNGVTLTTGARLKSTF 2695
            V   P FT      +K +    V    +++   D  P   + W KNG        ++ + 
Sbjct: 141  VDSPPTFTVSKLKREKTLIAMPVGNSLKLDCSADGKPRPTVVWLKNGKPFLKRDGVELSL 200

Query: 2696 DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
                  LS+      D G YTC  +N LG    T ++ + +R
Sbjct: 201  RPYQYVLSMRDAVPSDDGRYTCNVSNALGWINHTYTVDVRER 242



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 4/69 (5%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYK-STHDFSYVSLDITHTYEEDSGIY 2846
            G+++  +C+ +    PT  + W  N KP       + S   + YV L +      D G Y
Sbjct: 164  GNSLKLDCSADGKPRPT--VVWLKNGKPFLKRDGVELSLRPYQYV-LSMRDAVPSDDGRY 220

Query: 2847 TCKATNSKG 2855
            TC  +N+ G
Sbjct: 221  TCNVSNALG 229



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 15/49 (30%), Positives = 22/49 (44%)

Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
           V WLK+G+P      +          L+++     D G YTC   NA+G
Sbjct: 181 VVWLKNGKPFLKRDGVELSLRPYQYVLSMRDAVPSDDGRYTCNVSNALG 229



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 3/58 (5%)

Query: 945  WLKDGRPVEAS-SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            W KDG+ +  S S         Y  L IK++   D+G YTC A    G+ + +  LT+
Sbjct: 86   WYKDGKKMSVSHSSRMRIKRLRY--LKIKNLDKEDSGRYTCVAKRPCGEISANITLTV 141


>SB_5639| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1384

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 79/310 (25%), Positives = 123/310 (39%), Gaps = 37/310 (11%)

Query: 276  KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335
            ++ E  + +    + G P+P VTW +N Q  + SN   +    N   L + N   SD+G 
Sbjct: 974  RVVEKMNVRIHCPIVGFPKPVVTWTRNNQD-VRSNAR-LFVDPNTNDLLINNILTSDTGQ 1031

Query: 336  YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395
            Y   A NP G    S ++++ S   + +    +  +T + ++              P  V
Sbjct: 1032 YICSAVNPIGEDEKSSFISIISEASAEIIRGNASLVTSSNRK--------------PVTV 1077

Query: 396  KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH-KILVNE--SGNHALMI 452
             +    +V  G      C V G P P + W  +  +I       + L+ +  SG   L+I
Sbjct: 1078 VIGNSLEVLSGTDVTIVCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILII 1137

Query: 453  TNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--------------S 498
              VT   SG   CVA N  G       + VIE +Q V     +R               +
Sbjct: 1138 AQVTKDVSGSYECVASNVGGADRVATSIQVIEAQQPVIEFISKRLQSLKDLSAVTATIGT 1197

Query: 499  TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
            T+ +  G  +VL   + G P P  +W  +G P+    E     D   + L IP     D+
Sbjct: 1198 TITLLAGAKLVLQCPSTGVPLPSTSWSLNGEPL----EKGGRADLRGTELVIPAVAGVDS 1253

Query: 559  AWYQCTAQNV 568
              YQCTA NV
Sbjct: 1254 GKYQCTASNV 1263



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 54/195 (27%), Positives = 86/195 (44%), Gaps = 21/195 (10%)

Query: 395  VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITN 454
            + + QD  V E    R  C + G P P VTW  N++ +R   N ++ V+ + N  L+I N
Sbjct: 967  ITIGQDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQDVRS--NARLFVDPNTND-LLINN 1023

Query: 455  VTLSDSGVVTCVARNKSGETAFQCRLNVIEK--EQVV------------APKFVERFSTL 500
            +  SD+G   C A N  GE      +++I +   +++             P  V   ++L
Sbjct: 1024 ILTSDTGQYICSAVNPIGEDEKSSFISIISEASAEIIRGNASLVTSSNRKPVTVVIGNSL 1083

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP---ELRIHTD-GGASTLDIPRAKAS 556
             V  G  V +     GTP+P I W+ DG+ I       +  +  D  G   L I +    
Sbjct: 1084 EVLSGTDVTIVCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKD 1143

Query: 557  DAAWYQCTAQNVAGS 571
             +  Y+C A NV G+
Sbjct: 1144 VSGSYECVASNVGGA 1158



 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 72/290 (24%), Positives = 115/290 (39%), Gaps = 24/290 (8%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G+P P + WY +  PI       I   +   I  I +++  +   +   A NR    K S
Sbjct: 494  GKPTPTVYWYSQGRPIAVGKAVTIG--NNLRIENIDKIYALE---YTCHAYNRRARTKES 548

Query: 4496 ANL--------VVEEKRRQGRGGIVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVY 4546
            + +        ++  +R+        PS  +T   N+ V +G  V +   V       + 
Sbjct: 549  SVVNVLDLAPPIIAAERKVISVDKTTPSMDITIGTNLTVMAGTDVVVRCPVKTRPEPGLS 608

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W   G    P      L+ D + TLL+      D+G Y C+A N+AG+ +      V+ P
Sbjct: 609  WRIRGLAFDPKTSRAKLQNDNS-TLLLSGLTKDDAGSYTCIARNNAGKDQKVTNIQVADP 667

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLK----DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
              K     Q+   ++    IE          V  G  +   C   G P P V W   +  
Sbjct: 668  Q-KPTIISQSGFKSSHESDIEMTVTIGIQTTVLSGITLTIICPTRGLPAPDVTWEMNNTN 726

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            ++P   F       E TL I     +D+G+ +CVA N+AG+ T  +KL V
Sbjct: 727  VRPGGRF----VVQEGTLTIRNLVKQDQGNIRCVARNAAGQDTATSKLNV 772



 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 74/298 (24%), Positives = 119/298 (39%), Gaps = 43/298 (14%)

Query: 4436 GEPLPLIKWYRENFPIKNSP---DFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
            G P P I W  +   I +      F +    S + ILII QV  + S  +  VA N GG 
Sbjct: 1099 GTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGSYECVASNVGGA 1158

Query: 4492 AKCSANLVVEE----------KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
             + + ++ V E          KR Q    +   + T+    + + +G  + L    TG  
Sbjct: 1159 DRVATSIQVIEAQQPVIEFISKRLQSLKDLSAVTATI-GTTITLLAGAKLVLQCPSTGVP 1217

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
                 W  NG+ ++   R  +    GT  L+I      DSGKY+C A N        ++ 
Sbjct: 1218 LPSTSWSLNGEPLEKGGRADLR---GT-ELVIPAVAGVDSGKYQCTASNVIALDSRASDV 1273

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-------VAEGQAIEFSCKIVGKPLPTV 4654
             V     +D  KP+ + A    ++ E +K  +          G ++E  C   G P PT+
Sbjct: 1274 TV-----RDPTKPKIRGAPKDMDLFEIMKLSVDVGSTITTIPGVSLELKCSAQGLPAPTI 1328

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            +W  G+ ++            D  TL++ +    D   Y CVA N AG  + +  L +
Sbjct: 1329 RWRLGEIVV------------DSDTLKLPQLKVGDSRTYTCVASNVAGNDSKSTVLNI 1374



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 53/211 (25%), Positives = 82/211 (38%), Gaps = 20/211 (9%)

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
           N  +  G D   +  +   P P ++W   G           +   N +TL +    K D+
Sbjct: 584 NLTVMAGTDVVVRCPVKTRPEPGLSWRIRGLAFDPKTSRAKLQNDN-STLLLSGLTKDDA 642

Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393
           G YT +A N  G       + V  P +  +  Q         +   E  IE++       
Sbjct: 643 GSYTCIARNNAGKDQKVTNIQVADPQKPTIISQSGF------KSSHESDIEMT------- 689

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            V +     V  G      C   G P P+VTW +N+  +R     + +V E     L I 
Sbjct: 690 -VTIGIQTTVLSGITLTIICPTRGLPAPDVTWEMNNTNVRP--GGRFVVQEG---TLTIR 743

Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
           N+   D G + CVARN +G+     +LNVI+
Sbjct: 744 NLVKQDQGNIRCVARNAAGQDTATSKLNVID 774



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 93/423 (21%), Positives = 156/423 (36%), Gaps = 47/423 (11%)

Query: 4418 QPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVED 4477
            Q  RV E    R      G P P++ W R N  ++++   ++      + L+I  +   D
Sbjct: 971  QDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQDVRSNA--RLFVDPNTNDLLINNILTSD 1028

Query: 4478 SAVFAAVAENR-GGTAKCSANLVVEEKRRQ---GRGGIV-----PPSFTLTAQNVNVTSG 4528
            +  +   A N  G   K S   ++ E   +   G   +V      P   +   ++ V SG
Sbjct: 1029 TGQYICSAVNPIGEDEKSSFISIISEASAEIIRGNASLVTSSNRKPVTVVIGNSLEVLSG 1088

Query: 4529 QLVRLDTKVTGTKPIDVYWLKNGKKV-QPDIRNKIL---EEDGTYTLLILEAYPQDSGKY 4584
              V +   V GT    ++W  +G ++     + + L   +  G   L+I +     SG Y
Sbjct: 1089 TDVTIVCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGSY 1148

Query: 4585 ECVAINSAGEAR--CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI-VAEGQAIE 4641
            ECVA N  G  R     + + +     +    + ++      +   +   I +  G  + 
Sbjct: 1149 ECVASNVGGADRVATSIQVIEAQQPVIEFISKRLQSLKDLSAVTATIGTTITLLAGAKLV 1208

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN-- 4699
              C   G PLP+  W    + ++      +  T     L I      D G Y+C A N  
Sbjct: 1209 LQCPSTGVPLPSTSWSLNGEPLEKGGRADLRGT----ELVIPAVAGVDSGKYQCTASNVI 1264

Query: 4700 ----SAGRVTV--AAKLKVT-QPDQADNLPALTPLRD----IVVYEGQPAQFKTQITSKI 4748
                 A  VTV    K K+   P   D    +    D    I    G   + K       
Sbjct: 1265 ALDSRASDVTVRDPTKPKIRGAPKDMDLFEIMKLSVDVGSTITTIPGVSLELKCSAQGLP 1324

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             PTI+W R G ++ ++   ++        L +G     D+ T+TC A+  AG    S  L
Sbjct: 1325 APTIRW-RLGEIVVDSDTLKL------PQLKVG-----DSRTYTCVASNVAGNDSKSTVL 1372

Query: 4809 VVK 4811
             +K
Sbjct: 1373 NIK 1375



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 58/241 (24%), Positives = 98/241 (40%), Gaps = 26/241 (10%)

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPA-TKDKPKPQTKAANAPPEI---IEPLKDKIVA 4635
            + G Y+C A   AG +   A  +  L   T      + KA+  P +    I       + 
Sbjct: 422  NEGTYQCKATRLAGASSTAAFTLKILALNTPTILSAKGKASFGPRDADVTITVGTTVTLY 481

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            +G  +   C ++GKP PTV WY   + I   K   +        LRI         +Y C
Sbjct: 482  KGTTLTIKCPVMGKPTPTVYWYSQGRPIAVGKAVTIGN-----NLRIENIDKIYALEYTC 536

Query: 4696 VAYNSAGRV--------------TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
             AYN   R                +AA+ KV   D+      +T   ++ V  G     +
Sbjct: 537  HAYNRRARTKESSVVNVLDLAPPIIAAERKVISVDKTTPSMDITIGTNLTVMAGTDVVVR 596

Query: 4742 TQITSKIKPTIQW-LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
              + ++ +P + W +R  A  P+T   ++  + +N+ LL+    ++D G++TC A   AG
Sbjct: 597  CPVKTRPEPGLSWRIRGLAFDPKTSRAKL--QNDNSTLLLSGLTKDDAGSYTCIARNNAG 654

Query: 4801 Q 4801
            +
Sbjct: 655  K 655



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 92/376 (24%), Positives = 159/376 (42%), Gaps = 58/376 (15%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            V E  N+ + C +  +G P   V W  N + V   +R   + D     L I +  ++DTG
Sbjct: 975  VVEKMNVRIHCPI--VGFPKPVVTWTRNNQDVRSNARL--FVDPNTNDLLINNILTSDTG 1030

Query: 1249 EYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVM 1308
            +Y   AVN +G    S+ + +I          +E + E I+   +A+  T   R+ +TV+
Sbjct: 1031 QYICSAVNPIGEDEKSSFISII----------SEASAEIIR--GNASLVTSSNRKPVTVV 1078

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH-RFRPAYEFDY 1367
                     +++E + GT+V + C ++  G  +  + W  +G  I +G  + +     D 
Sbjct: 1079 IG-------NSLEVLSGTDVTIVCPVR--GTPSPFIFWRHDGLRIASGQGKGQFLLGKDN 1129

Query: 1368 VALDLL---SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYL 1424
               D+L    V  + SG Y C A+N  G    + +++VI  +  ++E       +++Q L
Sbjct: 1130 SGRDILIIAQVTKDVSGSYECVASNVGGADRVATSIQVIEAQQPVIEFIS----KRLQSL 1185

Query: 1425 EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNL-KVEWFKN 1483
            +D S    T  I  ++T+              + G  +  +C   P T   L    W  N
Sbjct: 1186 KDLSAVTAT--IGTTITL--------------LAGAKLVLQC---PSTGVPLPSTSWSLN 1226

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS-TTDI 1542
            G+P+  G R     D     L I  +   DSG Y C A N++  D  +  +T R  T   
Sbjct: 1227 GEPLEKGGR----ADLRGTELVIPAVAGVDSGKYQCTASNVIALDSRASDVTVRDPTKPK 1282

Query: 1543 VRSTQNEAGLEQIQVL 1558
            +R    +  L +I  L
Sbjct: 1283 IRGAPKDMDLFEIMKL 1298



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 67/316 (21%), Positives = 119/316 (37%), Gaps = 39/316 (12%)

Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
           L +G     +  + G P P V W+  G+ +      + +T  N+  LR+ N  K  +  Y
Sbjct: 480 LYKGTTLTIKCPVMGKPTPTVYWYSQGRPIAVG---KAVTIGNN--LRIENIDKIYALEY 534

Query: 337 TLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVK 396
           T  A N       S  + V       +  +R     D    +T   ++I+          
Sbjct: 535 TCHAYNRRARTKESSVVNVLDLAPPIIAAERKVISVD----KTTPSMDIT---------- 580

Query: 397 VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT 456
           +  +  V  G      C V  RP P ++W I         +   L N+  N  L+++ +T
Sbjct: 581 IGTNLTVMAGTDVVVRCPVKTRPEPGLSWRIRGLAFDPKTSRAKLQND--NSTLLLSGLT 638

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVI--EKEQVVA--------PKFVERFSTLNVR--- 503
             D+G  TC+ARN +G+      + V   +K  +++           +E   T+ ++   
Sbjct: 639 KDDAGSYTCIARNNAGKDQKVTNIQVADPQKPTIISQSGFKSSHESDIEMTVTIGIQTTV 698

Query: 504 -EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             G  + +     G P P +TW+ +   + P     +       TL I      D    +
Sbjct: 699 LSGITLTIICPTRGLPAPDVTWEMNNTNVRPGGRFVVQ----EGTLTIRNLVKQDQGNIR 754

Query: 563 CTAQNVAGSTATRARL 578
           C A+N AG     ++L
Sbjct: 755 CVARNAAGQDTATSKL 770



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 88/358 (24%), Positives = 143/358 (39%), Gaps = 59/358 (16%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNP 1777
            +D+RV E         +  VG PK  V W RN   + ++ RL    +   + +N   +  
Sbjct: 971  QDLRVVEKMNVRIHCPI--VGFPKPVVTWTRNNQDVRSNARLFVDPNTNDLLINN--ILT 1026

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVE 1837
             D+G Y C A+N +GE   SS + + S+AS ++   + S       L  SS    R+ V 
Sbjct: 1027 SDTGQYICSAVNPIGEDEKSSFISIISEASAEIIRGNAS-------LVTSS---NRKPVT 1076

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH---RYR 1894
            V +  +           ++  G      C +   P P   + W  +G  + SG    ++ 
Sbjct: 1077 VVIGNS----------LEVLSGTDVTIVCPVRGTPSP--FIFWRHDGLRIASGQGKGQFL 1124

Query: 1895 TSND-FGFAALDILTVYGEDSGEYTCKAINNLG--QAVSSIRLNVQSKESIIRDSQHESA 1951
               D  G   L I  V  + SG Y C A N  G  +  +SI++ +++++ +I     E  
Sbjct: 1125 LGKDNSGRDILIIAQVTKDVSGSYECVASNVGGADRVATSIQV-IEAQQPVI-----EFI 1178

Query: 1952 LEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRV 2011
             +++Q L+D S     +            G  I    +  G  + L+   T V  P    
Sbjct: 1179 SKRLQSLKDLSAVTATI------------GTTI---TLLAGAKLVLQCPSTGV--PLPST 1221

Query: 2012 EWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             W  NG P+++G R     D     L I      D+G Y C A+N +      S V V
Sbjct: 1222 SWSLNGEPLEKGGR----ADLRGTELVIPAVAGVDSGKYQCTASNVIALDSRASDVTV 1275



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 69/263 (26%), Positives = 107/263 (40%), Gaps = 39/263 (14%)

Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG 3751
            P     T+ +   + + +G  +   C V  +G PT  + W+  GRP A G  V   N+  
Sbjct: 465  PRDADVTITVGTTVTLYKGTTLTIKCPV--MGKPTPTVYWYSQGRPIAVGKAVTIGNNLR 522

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
                +ID IYA    EYTC A N+      ++ +        VL+   P   +  K+  +
Sbjct: 523  I--ENIDKIYAL---EYTCHAYNRRARTKESSVVN-------VLDLAPPIIAAERKVISV 570

Query: 3812 ERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKL 3871
            ++             +TP   IT   + TV     V   C V+ + +P L   W   G  
Sbjct: 571  DK-------------TTPSMDITIGTNLTVMAGTDVVVRCPVKTRPEPGL--SWRIRGLA 615

Query: 3872 L-PSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED--FTKATISCKKLPDII 3928
              P   R +   D   + L  L    +D+G Y C A N+ G+D   T   ++  + P II
Sbjct: 616  FDPKTSRAKLQNDNSTLLLSGL--TKDDAGSYTCIARNNAGKDQKVTNIQVADPQKPTII 673

Query: 3929 LQNQVPRGMKRS-EALTQMEATI 3950
             Q+    G K S E+  +M  TI
Sbjct: 674  SQS----GFKSSHESDIEMTVTI 692



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 71/309 (22%), Positives = 115/309 (37%), Gaps = 48/309 (15%)

Query: 280  GADAQFQVQLSGNPRPRVTWFKNGQRLINSN-KHEIITTHNHT---TLRVRNTQKSDSGH 335
            G D      + G P P + W  +G R+ +   K + +   +++    L +    K  SG 
Sbjct: 1088 GTDVTIVCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGS 1147

Query: 336  YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395
            Y  +A N  G    +  + V    +  ++     +I+   Q         S K L+    
Sbjct: 1148 YECVASNVGGADRVATSIQVIEAQQPVIE-----FISKRLQ---------SLKDLSAVTA 1193

Query: 396  KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
             +     +  G      C  TG P P  +W +N   +       +   E     L+I  V
Sbjct: 1194 TIGTTITLLAGAKLVLQCPSTGVPLPSTSWSLNGEPLEKGGRADLRGTE-----LVIPAV 1248

Query: 456  TLSDSGVVTCVARNKSGETAFQCRLNVIE--KEQVV-APKFVERF----------STLNV 502
               DSG   C A N     +    + V +  K ++  APK ++ F          ST+  
Sbjct: 1249 AGVDSGKYQCTASNVIALDSRASDVTVRDPTKPKIRGAPKDMDLFEIMKLSVDVGSTITT 1308

Query: 503  REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
              G  + L   A G P P I W+          E+ + +D    TL +P+ K  D+  Y 
Sbjct: 1309 IPGVSLELKCSAQGLPAPTIRWRLG--------EIVVDSD----TLKLPQLKVGDSRTYT 1356

Query: 563  CTAQNVAGS 571
            C A NVAG+
Sbjct: 1357 CVASNVAGN 1365



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 45/187 (24%), Positives = 70/187 (37%), Gaps = 11/187 (5%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V  G  +   C +  +P P + W        P K  +     D  TL +S    +D G Y
Sbjct: 587  VMAGTDVVVRCPVKTRPEPGLSWRIRGLAFDP-KTSRAKLQNDNSTLLLSGLTKDDAGSY 645

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQAD--NLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
             C+A N+AG+      ++V  P +    +        +  +        +T + S I  T
Sbjct: 646  TCIARNNAGKDQKVTNIQVADPQKPTIISQSGFKSSHESDIEMTVTIGIQTTVLSGITLT 705

Query: 4752 IQWLREGALIPETP---DFQMIHEGNNAV-----LLIGNTYEEDTGTFTCRATTAAGQVE 4803
            I     G   P+     +   +  G   V     L I N  ++D G   C A  AAGQ  
Sbjct: 706  IICPTRGLPAPDVTWEMNNTNVRPGGRFVVQEGTLTIRNLVKQDQGNIRCVARNAAGQDT 765

Query: 4804 TSAKLVV 4810
             ++KL V
Sbjct: 766  ATSKLNV 772



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 78/347 (22%), Positives = 129/347 (37%), Gaps = 51/347 (14%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV---LEILGTKTTDSGTYSCRATNKWG 3130
            P  D++M I+WF  G   E     R     G+     L I      + GTY C+AT   G
Sbjct: 377  PDEDKAM-IQWFTEGGFYEIKRFQRYEDDVGIDDEGNLHIRSVGRFNEGTYQCKATRLAG 435

Query: 3131 Q---AEISVKLECVD-----KSKGQK---PR---FTTHIQNIEGLKDGQSAHFECTVVPV 3176
                A  ++K+  ++      +KG+    PR    T  +     L  G +   +C V+  
Sbjct: 436  ASSTAAFTLKILALNTPTILSAKGKASFGPRDADVTITVGTTVTLYKGTTLTIKCPVM-- 493

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
              P   + WY  G+P+     +   ++     +D  Y       EY C AYN+       
Sbjct: 494  GKPTPTVYWYSQGRPIAVGKAVTIGNNLRIENIDKIYAL-----EYTCHAYNRRARTKES 548

Query: 3237 ATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVE 3296
            + +N        +  L P  +A  R++ S+        +TPS +       I   T L  
Sbjct: 549  SVVN--------VLDLAPPIIAAERKVISVD------KTTPSMD-------ITIGTNLTV 587

Query: 3297 GQSAHFEARLVPVDDPDLKVEWFYNGKKL-PHGHRYRTFHDFGIVILDILYCYEENSGEY 3355
                    R      P+  + W   G    P   R +  +D   ++L  L   ++++G Y
Sbjct: 588  MAGTDVVVRCPVKTRPEPGLSWRIRGLAFDPKTSRAKLQNDNSTLLLSGL--TKDDAGSY 645

Query: 3356 ECVATNKLGRDSTKANLKCT--SKENLILDSQLPRGMEGGLEKLQTL 3400
             C+A N  G+D    N++     K  +I  S      E  +E   T+
Sbjct: 646  TCIARNNAGKDQKVTNIQVADPQKPTIISQSGFKSSHESDIEMTVTI 692



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 111/493 (22%), Positives = 181/493 (36%), Gaps = 83/493 (16%)

Query: 1191 EGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEY 1250
            +G  I ++CR  P  D  M ++WF  G    +  RF+ Y D   V +D       D G  
Sbjct: 366  KGSEITVKCRT-PDEDKAM-IQWFTEGGFYEI-KRFQRYEDD--VGID-------DEGNL 413

Query: 1251 TVRAVNHLGSA-HTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVRE-DITVM 1308
             +R+V       +     R+   S     T    A+    +L    + +   R+ D+T+ 
Sbjct: 414  HIRSVGRFNEGTYQCKATRLAGASSTAAFTLKILALNTPTILSAKGKASFGPRDADVTIT 473

Query: 1309 QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYV 1368
                       +   +GT + ++C +  +G  T  V W+  G+PI  G            
Sbjct: 474  VGT-------TVTLYKGTTLTIKCPV--MGKPTPTVYWYSQGRPIAVGKAVTIGNNLRIE 524

Query: 1369 ALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTS 1428
             +D   +Y  +   YTC A N+      S  + V+     I+ ++      K+  ++   
Sbjct: 525  NID--KIYALE---YTCHAYNRRARTKESSVVNVLDLAPPIIAAE-----RKVISVD--- 571

Query: 1429 RYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNG---Q 1485
              K T  +D  +TI             V+ G  V   C ++   +  L   W   G    
Sbjct: 572  --KTTPSMD--ITIGTNL--------TVMAGTDVVVRCPVKTRPEPGL--SWRIRGLAFD 617

Query: 1486 PVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRS 1545
            P T   R +  +D   + L    L  +D+G YTC A N  G D+       + T   V  
Sbjct: 618  PKT--SRAKLQNDNSTLLLS--GLTKDDAGSYTCIARNNAGKDQ-------KVTNIQVAD 666

Query: 1546 TQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVS 1605
             Q    + Q          H +D+  E+T    I TT L  + +          R +P  
Sbjct: 667  PQKPTIISQ----SGFKSSHESDI--EMTVTIGIQTTVLSGITL----TIICPTRGLPAP 716

Query: 1606 DATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG-EAVTS 1664
            D T    W  NN  ++ G RF          L I + + +D G   C A NA G +  TS
Sbjct: 717  DVT----WEMNNTNVRPGGRFVVQEG----TLTIRNLVKQDQGNIRCVARNAAGQDTATS 768

Query: 1665 GIAIVHSKKSIYL 1677
             + ++     + L
Sbjct: 769  KLNVIDCYSEVSL 781



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 81/364 (22%), Positives = 140/364 (38%), Gaps = 63/364 (17%)

Query: 3141 VDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKT 3200
            ++   G++ R T   Q++  + +  +    C +V    P   + W  N Q +R + R+  
Sbjct: 957  IEDGDGEEARITIG-QDLR-VVEKMNVRIHCPIVGFPKP--VVTWTRNNQDVRSNARLFV 1012

Query: 3201 VSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLESLQPDSLAKI 3260
              +   ++++   T   D+G+Y+C A N  GED          +   ++  +   S   I
Sbjct: 1013 DPNTNDLLINNILTS--DTGQYICSAVNPIGED----------EKSSFISIISEASAEII 1060

Query: 3261 RELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPV-DDPDLKVEWF 3319
            R   SL  +  + P T           I +  +++ G        + PV   P   + W 
Sbjct: 1061 RGNASLVTSSNRKPVT---------VVIGNSLEVLSGTDVTI---VCPVRGTPSPFIFWR 1108

Query: 3320 YNGKKLPHGHRYRTF----HDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCT 3375
            ++G ++  G     F     + G  IL I    ++ SG YECVA+N  G D    +++  
Sbjct: 1109 HDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGSYECVASNVGGADRVATSIQ-- 1166

Query: 3376 SKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTSVEEEKGKAPVFTVPLSNIENLREG 3435
                 ++++Q P  +E   ++LQ+L+D                    T  +     L  G
Sbjct: 1167 -----VIEAQQP-VIEFISKRLQSLKD----------------LSAVTATIGTTITLLAG 1204

Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLC 3495
              A    +   T  P     W  NG+ L+ G R     D     L I      DSG+Y C
Sbjct: 1205 --AKLVLQCPSTGVPLPSTSWSLNGEPLEKGGR----ADLRGTELVIPAVAGVDSGKYQC 1258

Query: 3496 RAYN 3499
             A N
Sbjct: 1259 TASN 1262



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 88/359 (24%), Positives = 138/359 (38%), Gaps = 60/359 (16%)

Query: 1611 VEWYHNNKPLKSGSR-FTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
            V W  NN+ ++S +R F + N    +   I + L  D+G Y C A+N +GE   S    +
Sbjct: 995  VTWTRNNQDVRSNARLFVDPNTNDLL---INNILTSDTGQYICSAVNPIGEDEKSSFISI 1051

Query: 1670 HSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAH 1729
             S+ S  +   +   +   N+   T           V+    +  +   D+ +       
Sbjct: 1052 ISEASAEIIRGNASLVTSSNRKPVT-----------VVIGNSLEVLSGTDVTI------- 1093

Query: 1730 FEARLIPV-GDPKLRVEWLRNGVPIEASNR----LTTMHDFGYVALNMKYVNPEDSGTYT 1784
                + PV G P   + W  +G+ I +       L    + G   L +  V  + SG+Y 
Sbjct: 1094 ----VCPVRGTPSPFIFWRHDGLRIASGQGKGQFLLGKDNSGRDILIIAQVTKDVSGSYE 1149

Query: 1785 CRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAP 1844
            C A N +G A   +T       S+Q+    +  ++ I     S R Q  +D+        
Sbjct: 1150 CVASN-VGGADRVAT-------SIQVIEAQQPVIEFI-----SKRLQSLKDLSAVTATIG 1196

Query: 1845 RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAAL 1904
              IT L G  KL        +C     P P+    W  NG+ L+ G R     D     L
Sbjct: 1197 TTITLLAG-AKLV------LQCPSTGVPLPS--TSWSLNGEPLEKGGR----ADLRGTEL 1243

Query: 1905 DILTVYGEDSGEYTCKAIN--NLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDD 1961
             I  V G DSG+Y C A N   L    S + +   +K   IR +  +  L +I  L  D
Sbjct: 1244 VIPAVAGVDSGKYQCTASNVIALDSRASDVTVRDPTKPK-IRGAPKDMDLFEIMKLSVD 1301



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 77   IFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQI 136
            I ++ R  +  N +    + G P PVV+WTR     V  N   +  +  T D  LLI  I
Sbjct: 969  IGQDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQD-VRSNA-RLFVDPNTND--LLINNI 1024

Query: 137  GPGDEGEYTCTARNQYGEAICSVYI 161
               D G+Y C+A N  GE   S +I
Sbjct: 1025 LTSDTGQYICSAVNPIGEDEKSSFI 1049



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 53/220 (24%), Positives = 87/220 (39%), Gaps = 32/220 (14%)

Query: 1737 VGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            +G P   V W   G PI     +T  ++     L ++ ++   +  YTC A N       
Sbjct: 493  MGKPTPTVYWYSQGRPIAVGKAVTIGNN-----LRIENIDKIYALEYTCHAYNRRARTKE 547

Query: 1797 SSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKL 1856
            SS + V     L L     +A +K+  ++ ++      D+ +  N              +
Sbjct: 548  SSVVNV-----LDLAPPIIAAERKVISVDKTTPSM---DITIGTNLT------------V 587

Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQ-SGHRYRTSNDFGFAALDILTVYGEDSG 1915
              G      C ++  P+P +   W   G        R +  ND     L  LT   +D+G
Sbjct: 588  MAGTDVVVRCPVKTRPEPGL--SWRIRGLAFDPKTSRAKLQNDNSTLLLSGLTK--DDAG 643

Query: 1916 EYTCKAINNLG--QAVSSIRLNVQSKESIIRDSQHESALE 1953
             YTC A NN G  Q V++I++    K +II  S  +S+ E
Sbjct: 644  SYTCIARNNAGKDQKVTNIQVADPQKPTIISQSGFKSSHE 683



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            V E   VR  C +     PK  + W RN + + S  R     D     L I  +   D+G
Sbjct: 975  VVEKMNVRIHCPIVGF--PKPVVTWTRNNQDVRSNARL--FVDPNTNDLLINNILTSDTG 1030

Query: 3901 EYICRAVNDFGEDFTKATIS 3920
            +YIC AVN  GED   + IS
Sbjct: 1031 QYICSAVNPIGEDEKSSFIS 1050



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 48/214 (22%), Positives = 78/214 (36%), Gaps = 34/214 (15%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTL---TTGARLKSTFDFGLVTLSINSLRND 2710
            ++ G  V +   V+ R +P L   W   G+     T+ A+L++       TL ++ L  D
Sbjct: 587  VMAGTDVVVRCPVKTRPEPGLS--WRIRGLAFDPKTSRAKLQNDNS----TLLLSGLTKD 640

Query: 2711 DSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXX 2770
            D+G YTC A N  G+     +I++ D          P  + + G                
Sbjct: 641  DAGSYTCIARNNAGKDQKVTNIQVADPQ-------KPTIISQSGFKSSHESDIEMTVTIG 693

Query: 2771 XXXXVFISHLNNIVCKEGDNIHFECNVEPSRD-PTLKIEWFFNNKPLPSGTRYKSTHDFS 2829
                V       I+C             P+R  P   + W  NN  +  G R+       
Sbjct: 694  IQTTVLSGITLTIIC-------------PTRGLPAPDVTWEMNNTNVRPGGRFVVQEG-- 738

Query: 2830 YVSLDITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
              +L I +  ++D G   C A N+ G  T +  L
Sbjct: 739  --TLTIRNLVKQDQGNIRCVARNAAGQDTATSKL 770



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
            +D+ V E    +    I    KP + W R    +      ++  + N   LLI N    D
Sbjct: 971  QDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQDVRSNA--RLFVDPNTNDLLINNILTSD 1028

Query: 4788 TGTFTCRATTAAGQVETSAKLVVKSK 4813
            TG + C A    G+ E S+ + + S+
Sbjct: 1029 TGQYICSAVNPIGEDEKSSFISIISE 1054



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 17/62 (27%), Positives = 34/62 (54%), Gaps = 2/62 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            V W ++ + V +++R+  F +     L I ++   D G Y C A N IG+   S+ ++I+
Sbjct: 995  VTWTRNNQDVRSNARL--FVDPNTNDLLINNILTSDTGQYICSAVNPIGEDEKSSFISII 1052

Query: 1003 TK 1004
            ++
Sbjct: 1053 SE 1054



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 2/63 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   + W +N   + + ARL    D     L IN++   D+G Y C A N +GE   ++ 
Sbjct: 991  PKPVVTWTRNNQDVRSNARL--FVDPNTNDLLINNILTSDTGQYICSAVNPIGEDEKSSF 1048

Query: 2732 IKI 2734
            I I
Sbjct: 1049 ISI 1051



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 36/223 (16%)

Query: 3694 PPRFTVEIKDN-----IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLN 3748
            PP   V+ KD+     +   +G  +   CR  P  D  M I WF  G  +         +
Sbjct: 346  PPAIMVKCKDSDCGSSVWSVKGSEITVKCRT-PDEDKAM-IQWFTEGGFYEIKRFQRYED 403

Query: 3749 DFGFIA---LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSG 3805
            D G      L I  +   + G Y C+AT   G A++TA  T       +L    P  +S 
Sbjct: 404  DVGIDDEGNLHIRSVGRFNEGTYQCKATRLAG-ASSTAAFTLK-----ILALNTPTILSA 457

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
                   +G+ S  P++  +  T    +T  K  T      +  +C V  K  P   + W
Sbjct: 458  -------KGKASFGPRDADVTITVGTTVTLYKGTT------LTIKCPVMGKPTP--TVYW 502

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
            Y  G+ +  G       ++   ++D +Y       EY C A N
Sbjct: 503  YSQGRPIAVGKAVTIGNNLRIENIDKIYAL-----EYTCHAYN 540



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 3604 SRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPS 3663
            SR K  ND   ++L   G+ + DAG YTC A N  G+      +QV   Q   +  Q  S
Sbjct: 621  SRAKLQNDNSTLLLS--GLTKDDAGSYTCIARNNAGKDQKVTNIQVADPQKPTIISQ--S 676

Query: 3664 HFKSGTESIQKLEETL 3679
             FKS  ES  ++  T+
Sbjct: 677  GFKSSHESDIEMTVTI 692



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 8/89 (8%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLL--SVY 1376
            ++  VE  NV + C +  VG     V W  N + +++  R       D    DLL  ++ 
Sbjct: 972  DLRVVEKMNVRIHCPI--VGFPKPVVTWTRNNQDVRSNARLF----VDPNTNDLLINNIL 1025

Query: 1377 PEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
              D+G Y C A N +GE   S  + +I++
Sbjct: 1026 TSDTGQYICSAVNPIGEDEKSSFISIISE 1054



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 6/75 (8%)

Query: 663  VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI--QDSGEYTCRAVSATGVA 720
            VG P   + W +N Q + +++R   +F     + D+L  NI   D+G+Y C AV+  G  
Sbjct: 988  VGFPKPVVTWTRNNQDVRSNAR---LFVDPNTN-DLLINNILTSDTGQYICSAVNPIGED 1043

Query: 721  ETKAVLHVTPRATIE 735
            E  + + +   A+ E
Sbjct: 1044 EKSSFISIISEASAE 1058



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 7/87 (8%)

Query: 2915 IPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLV 2974
            I +     L +G  L ++  V  K  P   + WY  G+ +  G    + ++     +D +
Sbjct: 472  ITVGTTVTLYKGTTLTIKCPVMGKPTPT--VYWYSQGRPIAVGKAVTIGNNLRIENIDKI 529

Query: 2975 DVYERDSGIYTCKAYNKRGEAFTSSTV 3001
               E     YTC AYN+R     SS V
Sbjct: 530  YALE-----YTCHAYNRRARTKESSVV 551



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 17/78 (21%), Positives = 36/78 (46%), Gaps = 2/78 (2%)

Query: 2115 LTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYT 2174
            +T  ++L+  ++ +       +  P   + W  N Q +R+  R     +   + ++ + T
Sbjct: 967  ITIGQDLRVVEKMNVRIHCPIVGFPKPVVTWTRNNQDVRSNARLFVDPNTNDLLINNILT 1026

Query: 2175 YAEDSGTYMCKATNKLGE 2192
               D+G Y+C A N +GE
Sbjct: 1027 --SDTGQYICSAVNPIGE 1042



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            VG P   V W RN + +  ++R+    D     + I+++   D G Y+C A N +GE
Sbjct: 988  VGFPKPVVTWTRNNQDVRSNARLFV--DPNTNDLLINNILTSDTGQYICSAVNPIGE 1042


>SB_10900| Best HMM Match : I-set (HMM E-Value=0)
          Length = 1642

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 97/393 (24%), Positives = 145/393 (36%), Gaps = 43/393 (10%)

Query: 4413 FTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPI-KNSPDFQIHTFSTKSILIIR 4471
            FTK+      F+  Q  FE +  G   P   W ++   + K + D +    ++ S L I 
Sbjct: 29   FTKQPSSQLGFKGLQVEFECQVSGIANPSYYWIKDGTNVTKGTQDVK----NSISSLTIS 84

Query: 4472 QVFVEDSAVFAAVAENRGG-TAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
             +   D+  +  VA      T   +A L V     QG      P  T      +   GQ 
Sbjct: 85   GLKFTDAGQYVCVATGIATLTTSTAATLTV-----QGS-----PDITQGPTGTSPHVGQE 134

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
                   T      V W       QP  R+      G  +L+I +    D+G Y C+  N
Sbjct: 135  AIFHCIATANPSPSVSWTNPFD--QPINRSGRFTVYGNGSLVISDVKKADTGYYTCIVSN 192

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
            S G A+  A+  V      D P        A P       ++   EG  I F C   G P
Sbjct: 193  SFGSAKAFAQLTVL-----DAP--------AAPSFTTTPTNQTAREGSDITFYCMASGVP 239

Query: 4651 LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
             PT+ W+K   +I  ++  +    A    +RI    P D+G Y C A NS G       L
Sbjct: 240  TPTITWHKVGGVILSNRTDKPRPGA----IRIQSVIPSDDGSYVCEAINSEGTKRADVYL 295

Query: 4711 KVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKPTIQW-LREGALIPETPDFQ 4768
            ++      +  P  T    D+V  E    +    +     P++ W L  GA+   T    
Sbjct: 296  RI------EGFPRFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWILPSGAIATVTSPAS 349

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             +    N  L+IGN  E + G + C A  + G+
Sbjct: 350  RVQVLANHTLVIGNATESEYGEYVCVAKNSVGE 382



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 79/321 (24%), Positives = 123/321 (38%), Gaps = 48/321 (14%)

Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
           L P       ++P +    +G   +F+ Q+SG   P   W K+G  +    +      ++
Sbjct: 21  LAPCLSQSFTKQPSSQLGFKGLQVEFECQVSGIANPSYYWIKDGTNVTKGTQD---VKNS 77

Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRET 379
            ++L +   + +D+G Y         C+ T G   + + T + +  Q S  IT   Q  T
Sbjct: 78  ISSLTISGLKFTDAGQYV--------CVAT-GIATLTTSTAATLTVQGSPDIT---QGPT 125

Query: 380 EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
                + ++A+                    F C  T  P P V+W           N  
Sbjct: 126 GTSPHVGQEAI--------------------FHCIATANPSPSVSW---TNPFDQPINRS 162

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
                 GN +L+I++V  +D+G  TC+  N  G      +L V++     AP F    + 
Sbjct: 163 GRFTVYGNGSLVISDVKKADTGYYTCIVSNSFGSAKAFAQLTVLDAP--AAPSFTTTPTN 220

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTD-GGASTLDIPRAKASDA 558
              REG  +     A G PTP ITW K G  I+ N      TD      + I     SD 
Sbjct: 221 QTAREGSDITFYCMASGVPTPTITWHKVGGVILSN-----RTDKPRPGAIRIQSVIPSDD 275

Query: 559 AWYQCTAQNVAGSTATRARLY 579
             Y C A N  G+   RA +Y
Sbjct: 276 GSYVCEAINSEGT--KRADVY 294



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 58/197 (29%), Positives = 82/197 (41%), Gaps = 19/197 (9%)

Query: 388 KALAPQFVKVCQ-DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
           + + P  +KV   ++ V  G   R DC+  G P P +TW  +   +     H +    + 
Sbjct: 472 RVIVPPSIKVPPTNQSVALGATARLDCQADGDPPPLMTWETSQGSVIGQARHTV----AA 527

Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
           N  L+IT  T  D+G +TC A N +G T  +  L + +      P FV+  S   + +G 
Sbjct: 528 NGTLIITMATAGDTGWLTCTATNAAGSTVKKAYLTISD-----VPVFVQLPSHQTLVKGN 582

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS----TLDIPRAKASDAAWYQ 562
            + L  RA     P ITW K       +  L+  T  G S     L        D   Y 
Sbjct: 583 AITLPCRATAADAPVITWFKAD----QSGALQQLTSSGVSQANGDLSFASVTRQDRGMYA 638

Query: 563 CTAQNVAGSTAT-RARL 578
           C A N AG T T RA L
Sbjct: 639 CQACNAAGCTMTPRASL 655



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 70/263 (26%), Positives = 101/263 (38%), Gaps = 28/263 (10%)

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            IVPPS  +   N +V  G   RLD +  G  P  + W  +   V    R+ +       T
Sbjct: 474  IVPPSIKVPPTNQSVALGATARLDCQADGDPPPLMTWETSQGSVIGQARHTVAANG---T 530

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVS-LPATKDKPKPQTKAANAPPEIIEPL 4629
            L+I  A   D+G   C A N+AG     A   +S +P     P  QT             
Sbjct: 531  LIITMATAGDTGWLTCTATNAAGSTVKKAYLTISDVPVFVQLPSHQT------------- 577

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
                + +G AI   C+      P + W+K D+     +      +     L  +    +D
Sbjct: 578  ----LVKGNAITLPCRATAADAPVITWFKADQSGALQQLTSSGVSQANGDLSFASVTRQD 633

Query: 4690 EGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
             G Y C A N+AG  +T  A L V       N     P  D+ V +G+ A+      S  
Sbjct: 634  RGMYACQACNAAGCTMTPRASLNVLY-----NPLFPVPPPDVGVIQGEDAKLMCAPDSNP 688

Query: 4749 KPTIQWLR-EGALIPETPDFQMI 4770
              TI W R +G  +P T   Q+I
Sbjct: 689  PATISWSRPDGTALPGTGYEQVI 711



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 76/321 (23%), Positives = 122/321 (38%), Gaps = 45/321 (14%)

Query: 252 ISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311
           ++T    +L     P I Q P  +    G +A F    + NP P V+W     + IN + 
Sbjct: 104 LTTSTAATLTVQGSPDITQGPTGTSPHVGQEAIFHCIATANPSPSVSWTNPFDQPINRSG 163

Query: 312 HEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYI 371
               T + + +L + + +K+D+G+YT        CIV++ +       +++ Q       
Sbjct: 164 R--FTVYGNGSLVISDVKKADTGYYT--------CIVSNSF----GSAKAFAQ------- 202

Query: 372 TDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ 431
                      + + +   AP F     ++   EG    F C  +G P P +TW      
Sbjct: 203 -----------LTVLDAPAAPSFTTTPTNQTAREGSDITFYCMASGVPTPTITWHKVGGV 251

Query: 432 IRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
           I  +   K      G  A+ I +V  SD G   C A N  G       L +        P
Sbjct: 252 ILSNRTDK---PRPG--AIRIQSVIPSDDGSYVCEAINSEGTKRADVYLRI-----EGFP 301

Query: 492 KFVERFSTLNVREGEPVVLNARAVGTPTPRITW--QKDGVPIIPNPELRIHTDGGASTLD 549
           +F    S +   E   V L+    G PTP ++W      +  + +P  R+       TL 
Sbjct: 302 RFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWILPSGAIATVTSPASRVQVLAN-HTLV 360

Query: 550 IPRAKASDAAWYQCTAQNVAG 570
           I  A  S+   Y C A+N  G
Sbjct: 361 IGNATESEYGEYVCVAKNSVG 381



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 106/423 (25%), Positives = 155/423 (36%), Gaps = 62/423 (14%)

Query: 4393 KAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIK 4452
            KA  Q  V++ P  PS    FT         E     F     G P P I W++    I 
Sbjct: 198  KAFAQLTVLDAPAAPS----FTTTPTNQTAREGSDITFYCMASGVPTPTITWHKVGGVIL 253

Query: 4453 NSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV 4512
            ++   +    + +    I+ V   D   +   A N  GT +    L +E        G  
Sbjct: 254  SNRTDKPRPGAIR----IQSVIPSDDGSYVCEAINSEGTKRADVYLRIE--------GF- 300

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV----QPDIRNKILEEDGT 4568
             P FTL+  +V       V+LD  V G     V W+     +     P  R ++L     
Sbjct: 301  -PRFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWILPSGAIATVTSPASRVQVL---AN 356

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
            +TL+I  A   + G+Y CVA NS GE     +  VS+      P   ++  N    I  P
Sbjct: 357  HTLVIGNATESEYGEYVCVAKNSVGEKT--RKVTVSILTV---PSFNSQLLN----ISRP 407

Query: 4629 LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            ++D +          C   G P P   W  G K++        SRT    +L ++     
Sbjct: 408  IRDNVT-------IMCPSRGNPSPHHLWTFGGKILS------QSRTLSLVSLNVT----- 449

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            + G Y C   NS G   ++  L+V  P          P  +  V  G  A+   Q     
Sbjct: 450  NRGYYTCHLNNSMGSAELSFFLRVIVPPSIK-----VPPTNQSVALGATARLDCQADGDP 504

Query: 4749 KPTIQW-LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             P + W   +G++I +           N  L+I      DTG  TC AT AAG     A 
Sbjct: 505  PPLMTWETSQGSVIGQARHTVAA----NGTLIITMATAGDTGWLTCTATNAAGSTVKKAY 560

Query: 4808 LVV 4810
            L +
Sbjct: 561  LTI 563



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 8/134 (5%)

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
           S +  L + ++ +++ G  TC   N  G       L VI    +  P      +  +V  
Sbjct: 436 SQSRTLSLVSLNVTNRGYYTCHLNNSMGSAELSFFLRVIVPPSIKVPP-----TNQSVAL 490

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           G    L+ +A G P P +TW+     +I       HT     TL I  A A D  W  CT
Sbjct: 491 GATARLDCQADGDPPPLMTWETSQGSVIGQAR---HTVAANGTLIITMATAGDTGWLTCT 547

Query: 565 AQNVAGSTATRARL 578
           A N AGST  +A L
Sbjct: 548 ATNAAGSTVKKAYL 561



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 6/170 (3%)

Query: 360 ESYVQDQRSQYITDTQQRETEERIEISEKALA-PQFVKVCQDRDVTEGKMTRFDCRVTGR 418
           +S +      Y+ +    E  +R ++  +    P+F     D    E    + DC V G 
Sbjct: 268 QSVIPSDDGSYVCEAINSEGTKRADVYLRIEGFPRFTLSPSDVVAPEFSEVKLDCLVAGD 327

Query: 419 PYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQC 478
           P P V+W +    I    +    V    NH L+I N T S+ G   CVA+N  GE   + 
Sbjct: 328 PTPSVSWILPSGAIATVTSPASRVQVLANHTLVIGNATESEYGEYVCVAKNSVGEKTRKV 387

Query: 479 RLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
            ++++       P F  +   ++    + V +   + G P+P   W   G
Sbjct: 388 TVSIL-----TVPSFNSQLLNISRPIRDNVTIMCPSRGNPSPHHLWTFGG 432



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 93/395 (23%), Positives = 136/395 (34%), Gaps = 54/395 (13%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT         E  + + +    G+P P + W          P   I T ++ +  + 
Sbjct: 301  PRFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWIL--------PSGAIATVTSPASRV- 351

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP-PSFTLTAQNVNVTSGQ 4529
             QV    + V     E+  G   C A   V EK R+    I+  PSF     N++     
Sbjct: 352  -QVLANHTLVIGNATESEYGEYVCVAKNSVGEKTRKVTVSILTVPSFNSQLLNISRPIRD 410

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             V +     G       W   GK         IL +  T +L+ L     + G Y C   
Sbjct: 411  NVTIMCPSRGNPSPHHLWTFGGK---------ILSQSRTLSLVSLNV--TNRGYYTCHLN 459

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            NS G A       V +P                P I  P  ++ VA G      C+  G 
Sbjct: 460  NSMGSAELSFFLRVIVP----------------PSIKVPPTNQSVALGATARLDCQADGD 503

Query: 4650 PLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            P P + W      +I  +++      A   TL I+ A   D G   C A N+AG     A
Sbjct: 504  PPPLMTWETSQGSVIGQARH----TVAANGTLIITMATAGDTGWLTCTATNAAGSTVKKA 559

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR---EGALIPETP 4765
             L ++       LP+   L      +G       + T+   P I W +    GAL   T 
Sbjct: 560  YLTISDVPVFVQLPSHQTL-----VKGNAITLPCRATAADAPVITWFKADQSGALQQLTS 614

Query: 4766 DFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
                   G+   L   +   +D G + C+A  AAG
Sbjct: 615  SGVSQANGD---LSFASVTRQDRGMYACQACNAAG 646



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 4/112 (3%)

Query: 253 STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
           S E+   L  + PP I   P N  +  GA A+   Q  G+P P +TW  +   +I   +H
Sbjct: 464 SAELSFFLRVIVPPSIKVPPTNQSVALGATARLDCQADGDPPPLMTWETSQGSVIGQARH 523

Query: 313 EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
              T   + TL +      D+G  T  A N  G  V   YL + S    +VQ
Sbjct: 524 ---TVAANGTLIITMATAGDTGWLTCTATNAAGSTVKKAYLTI-SDVPVFVQ 571



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 50/178 (28%), Positives = 76/178 (42%), Gaps = 15/178 (8%)

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694
            +G  +EF C++ G   P+  W K G  + K ++  + S ++    L IS     D G Y 
Sbjct: 40   KGLQVEFECQVSGIANPSYYWIKDGTNVTKGTQDVKNSISS----LTISGLKFTDAGQYV 95

Query: 4695 CVAYNSAGRVT-VAAKLKVT-QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI 4752
            CVA   A   T  AA L V   PD        +P      + GQ A F    T+   P++
Sbjct: 96   CVATGIATLTTSTAATLTVQGSPDITQGPTGTSP------HVGQEAIFHCIATANPSPSV 149

Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             W       P     +    GN + L+I +  + DTG +TC  + + G  +  A+L V
Sbjct: 150  SWTNPFDQ-PINRSGRFTVYGNGS-LVISDVKKADTGYYTCIVSNSFGSAKAFAQLTV 205



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 45/160 (28%), Positives = 64/160 (40%), Gaps = 13/160 (8%)

Query: 3073 IPTGDQSMVIEWFYN-GKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            I T + S  + W     + I  S R  TVY  G +V+     K  D+G Y+C  +N +G 
Sbjct: 140  IATANPSPSVSWTNPFDQPINRSGRF-TVYGNGSLVIS--DVKKADTGYYTCIVSNSFGS 196

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
            A+   +L  +D      P FTT   N +  ++G    F C    V  P   I W+  G  
Sbjct: 197  AKAFAQLTVLDAPAA--PSFTTTPTN-QTAREGSDITFYCMASGVPTP--TITWHKVGGV 251

Query: 3192 MRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +  +   K         + I      D G YVC A N  G
Sbjct: 252  ILSNRTDKPRPG----AIRIQSVIPSDDGSYVCEAINSEG 287



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 58/265 (21%), Positives = 96/265 (36%), Gaps = 20/265 (7%)

Query: 86  GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYT 145
           G  A F      NP+P VSWT    P  +    S R+    G+ SL+I  +   D G YT
Sbjct: 132 GQEAIFHCIATANPSPSVSWTN---PFDQPINRSGRFTVY-GNGSLVISDVKKADTGYYT 187

Query: 146 CTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQ 203
           C   N +G  +A   + +                  R  S+   +         T    +
Sbjct: 188 CIVSNSFGSAKAFAQLTVLDAPAAPSFTTTPTNQTAREGSDITFYCMASGVPTPTITWHK 247

Query: 204 TQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSF-RESITKRYVGESDVQISTEIDRSLGP 262
              V  +N TD       ++ +       + S+  E+I       +DV +  E       
Sbjct: 248 VGGVILSNRTDKPRPGAIRIQSVIPS--DDGSYVCEAINSEGTKRADVYLRIE------- 298

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF--KNGQRLINSNKHEIITTHNH 320
              P+    P +    E ++ +    ++G+P P V+W         + S    +    NH
Sbjct: 299 -GFPRFTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWILPSGAIATVTSPASRVQVLANH 357

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNG 345
            TL + N  +S+ G Y  +A+N  G
Sbjct: 358 -TLVIGNATESEYGEYVCVAKNSVG 381



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 6/97 (6%)

Query: 69  PSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
           P+ P F     N    +G +  F     G PTP ++W  K   ++  N+      ++   
Sbjct: 209 PAAPSFTTTPTNQTAREGSDITFYCMASGVPTPTITW-HKVGGVILSNR-----TDKPRP 262

Query: 129 VSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEG 165
            ++ I+ + P D+G Y C A N  G     VY++ EG
Sbjct: 263 GAIRIQSVIPSDDGSYVCEAINSEGTKRADVYLRIEG 299



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 5/91 (5%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP  +    N   A G  A+ + +  G+P P+++W   +  ++   ++++  N      +
Sbjct: 476 PPSIKVPPTNQSVALGATARLDCQADGDPPPLMTWETSQGSVIGQARHTVAANG-----T 530

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L+I     GD G  TCTA N  G  +   Y+
Sbjct: 531 LIITMATAGDTGWLTCTATNAAGSTVKKAYL 561



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 45/156 (28%), Positives = 60/156 (38%), Gaps = 12/156 (7%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP   V    N  V  G     DC+ +  GDP   + W    +    G   HT+   G  
Sbjct: 476  PPSIKVP-PTNQSVALGATARLDCQAD--GDPPPLMTW-ETSQGSVIGQARHTVAANG-- 529

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQG---MSGEKIKE 3810
             L I    A D G  TC ATN  GS    A +T S   D+ +  QLP     + G  I  
Sbjct: 530  TLIITMATAGDTGWLTCTATNAAGSTVKKAYLTIS---DVPVFVQLPSHQTLVKGNAITL 586

Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846
              R   +DAP      +     + Q+ S  V ++ G
Sbjct: 587  PCRATAADAPVITWFKADQSGALQQLTSSGVSQANG 622



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 15/127 (11%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD--GQ 3165
            L I G K TD+G Y C AT   G A ++         +G  P  T   Q   G     GQ
Sbjct: 81   LTISGLKFTDAGQYVCVAT---GIATLTTSTAATLTVQG-SPDIT---QGPTGTSPHVGQ 133

Query: 3166 SAHFECTVVPVDDPDMKIEWYHN-GQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
             A F C  +   +P   + W +   QP+  S R     +   V+ D+   +  D+G Y C
Sbjct: 134  EAIFHC--IATANPSPSVSWTNPFDQPINRSGRFTVYGNGSLVISDV---KKADTGYYTC 188

Query: 3225 RAYNKYG 3231
               N +G
Sbjct: 189  IVSNSFG 195



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 3/86 (3%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEW-FHNGKPLLTGSRVKTINDFGFVI 3616
            P FT +PSD++  E S    +C  +   D +  V W   +G      S    +       
Sbjct: 301  PRFTLSPSDVVAPEFSEVKLDC--LVAGDPTPSVSWILPSGAIATVTSPASRVQVLANHT 358

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEAT 3642
            L IG   + + G Y C A N  GE T
Sbjct: 359  LVIGNATESEYGEYVCVAKNSVGEKT 384



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 69/332 (20%), Positives = 124/332 (37%), Gaps = 35/332 (10%)

Query: 1090 NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV------ETRSSIDT 1143
            NR   +  +G  +L I+ V+  D+G YT +  N+ G A+  A +TV       + ++  T
Sbjct: 160  NRSGRFTVYGNGSLVISDVKKADTGYYTCIVSNSFGSAKAFAQLTVLDAPAAPSFTTTPT 219

Query: 1144 SSIHRGLYEKTRHIEESKFVEPMYQIEEIS---------KSKPVFVQPLSNPPPVSEGKN 1194
            +   R   + T +   S    P     ++          K +P  ++ + +  P  +G  
Sbjct: 220  NQTAREGSDITFYCMASGVPTPTITWHKVGGVILSNRTDKPRPGAIR-IQSVIPSDDGSY 278

Query: 1195 IHLECRLE--PMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTV 1252
            +      E     D  +R+E F      T+        +F  V LD + A         +
Sbjct: 279  VCEAINSEGTKRADVYLRIEGFPR---FTLSPSDVVAPEFSEVKLDCLVAGDPTPSVSWI 335

Query: 1253 RAVNHLGSAHTSAI-VRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP 1311
                 + +  + A  V+V+    +V     E    +   +   +   K  +  ++++  P
Sbjct: 336  LPSGAIATVTSPASRVQVLANHTLVIGNATESEYGEYVCVAKNSVGEKTRKVTVSILTVP 395

Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371
             F+  L NI      NV + C  +  G+ +    W   GK +                L 
Sbjct: 396  SFNSQLLNISRPIRDNVTIMCPSR--GNPSPHHLWTFGGKILSQSR-----------TLS 442

Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            L+S+   + G YTC   N +G A  S  LRVI
Sbjct: 443  LVSLNVTNRGYYTCHLNNSMGSAELSFFLRVI 474



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 4/61 (6%)

Query: 943  VEWLKD-GRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            V W     +P+  S R T +   G  +L I  V   D G+YTC   N+ G A   A LT+
Sbjct: 149  VSWTNPFDQPINRSGRFTVY---GNGSLVISDVKKADTGYYTCIVSNSFGSAKAFAQLTV 205

Query: 1002 V 1002
            +
Sbjct: 206  L 206



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 6/102 (5%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P FTTTP++    E S   F C    V   +  + W   G  +L+    K         +
Sbjct: 212  PSFTTTPTNQTAREGSDITFYCMASGVPTPT--ITWHKVGGVILSNRTDKPRPG----AI 265

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
             I  V   D G Y C+A N  G       L+++G     L P
Sbjct: 266  RIQSVIPSDDGSYVCEAINSEGTKRADVYLRIEGFPRFTLSP 307



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 7/77 (9%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGAR-LKSTFDFGLVTLSINSLRNDDSGI 2714
            +G  V  E QV    +P+    W K+G  +T G + +K++      +L+I+ L+  D+G 
Sbjct: 40   KGLQVEFECQVSGIANPSYY--WIKDGTNVTKGTQDVKNSIS----SLTISGLKFTDAGQ 93

Query: 2715 YTCKATNLLGEAVSTAS 2731
            Y C AT +     STA+
Sbjct: 94   YVCVATGIATLTTSTAA 110



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 7/95 (7%)

Query: 1843 APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFA 1902
            AP F T     T   EG    + C     P P   + W+  G V+ S    RT       
Sbjct: 211  APSFTTTPTNQTA-REGSDITFYCMASGVPTPT--ITWHKVGGVILSN---RTDKPRP-G 263

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            A+ I +V   D G Y C+AIN+ G   + + L ++
Sbjct: 264  AIRIQSVIPSDDGSYVCEAINSEGTKRADVYLRIE 298



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 9/126 (7%)

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
            +D G+Y C A N  G     V L    + +G  PRFT    ++    +      +C V  
Sbjct: 273  SDDGSYVCEAINSEGTKRADVYL----RIEG-FPRFTLSPSDVVA-PEFSEVKLDCLV-- 324

Query: 3176 VDDPDMKIEW-YHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDF 3234
              DP   + W   +G     ++    V       L I      + GEYVC A N  GE  
Sbjct: 325  AGDPTPSVSWILPSGAIATVTSPASRVQVLANHTLVIGNATESEYGEYVCVAKNSVGEKT 384

Query: 3235 TRATIN 3240
             + T++
Sbjct: 385  RKVTVS 390



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 90  KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149
           K +  + G+PTP VSW      +      + R  +   + +L+I      + GEY C A+
Sbjct: 319 KLDCLVAGDPTPSVSWILPSGAIATVTSPASRV-QVLANHTLVIGNATESEYGEYVCVAK 377

Query: 150 NQYGE 154
           N  GE
Sbjct: 378 NSVGE 382



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 8/92 (8%)

Query: 1847 ITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAAL 1904
            ITQ  GPT  S   GQ A + C     P P++     F+  + +SG R+     +G  +L
Sbjct: 120  ITQ--GPTGTSPHVGQEAIFHCIATANPSPSVSWTNPFDQPINRSG-RFTV---YGNGSL 173

Query: 1905 DILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             I  V   D+G YTC   N+ G A +  +L V
Sbjct: 174  VISDVKKADTGYYTCIVSNSFGSAKAFAQLTV 205



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 9/128 (7%)

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +I  V  S  G   C ARN+ G T  Q     IE   VV    +E  ST         ++
Sbjct: 710 VIVGVQPSHVGDYKCSARNEYGSTGEQTIRLTIETRAVVTDFTMETSST--------DLV 761

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                GTP P +TW    V +  N +   ++      L +P     +  +Y C A N   
Sbjct: 762 TCDVTGTPAPTVTWYLGNVKLPQNAKYPGYSVTRDDKLRLPIGTLKNNTFY-CNASNPHA 820

Query: 571 STATRARL 578
           S    A++
Sbjct: 821 SMRFLAKV 828



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 6/69 (8%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRN-EKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            GQ A F C  I   +P+  V W    ++ I  S R T    +G  S+ IS V+  D G Y
Sbjct: 132  GQEAIFHC--IATANPSPSVSWTNPFDQPINRSGRFTV---YGNGSLVISDVKKADTGYY 186

Query: 2450 MCRASNLLG 2458
             C  SN  G
Sbjct: 187  TCIVSNSFG 195



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 8/104 (7%)

Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704
           S    +G ++ FE ++  + +P+    W+K+G ++   ++ T   +    SL +  L   
Sbjct: 35  SQLGFKGLQVEFECQVSGIANPSYY--WIKDGTNV---TKGTQDVKNSISSLTISGLKFT 89

Query: 705 DSGEYTCRAVS-ATGVAETKAVLHV--TPRATIERTSQHPETLQ 745
           D+G+Y C A   AT    T A L V  +P  T   T   P   Q
Sbjct: 90  DAGQYVCVATGIATLTTSTAATLTVQGSPDITQGPTGTSPHVGQ 133



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 33/100 (33%), Positives = 42/100 (42%), Gaps = 8/100 (8%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P F     + TA EG  I F       G PT  I W K G  I  S+R T   R G I +
Sbjct: 212 PSFTTTPTNQTAREGSDITFYCMAS--GVPTPTITWHKVGGVI-LSNR-TDKPRPGAIRI 267

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT--PRATI 734
              S+   D G Y C A+++ G       L +   PR T+
Sbjct: 268 Q--SVIPSDDGSYVCEAINSEGTKRADVYLRIEGFPRFTL 305



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 4643 SCKIVGKPLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            +C + G P PTV WY G+ KL + +KY   S T D+  LR+     ++   Y C A N  
Sbjct: 762  TCDVTGTPAPTVTWYLGNVKLPQNAKYPGYSVTRDD-KLRLPIGTLKNNTFY-CNASNPH 819

Query: 4702 GRVTVAAKL 4710
              +   AK+
Sbjct: 820  ASMRFLAKV 828



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 15/90 (16%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSR-DPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            F S L NI     DN+   C   PSR +P+    W F  K L        +   S VSL+
Sbjct: 397  FNSQLLNISRPIRDNVTIMC---PSRGNPSPHHLWTFGGKIL------SQSRTLSLVSLN 447

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLR 2864
            +T+      G YTC   NS GSA  S  LR
Sbjct: 448  VTNR-----GYYTCHLNNSMGSAELSFFLR 472



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 5/98 (5%)

Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
           RV  PP   VP  + +   G     + + +  GDP   + W  +  S+   +R T +   
Sbjct: 472 RVIVPPSIKVPPTNQSVALGATARLDCQAD--GDPPPLMTWETSQGSVIGQARHT-VAAN 528

Query: 692 GYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
           G + + M +    D+G  TC A +A G    KA L ++
Sbjct: 529 GTLIITMATAG--DTGWLTCTATNAAGSTVKKAYLTIS 564



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P  K P  +Q S+  G  A  + + +  GD    + W      V   +R T   N G + 
Sbjct: 477  PSIKVPPTNQ-SVALGATARLDCQAD--GDPPPLMTWETSQGSVIGQARHTVAAN-GTLI 532

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            +T+   T  D G  TC A NA G     A LTI
Sbjct: 533  ITM--ATAGDTGWLTCTATNAAGSTVKKAYLTI 563



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 5/109 (4%)

Query: 2616 WEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLK 2675
            W       AA + V + ++   +   P+F   L S+  LV+G  + L  +      P   
Sbjct: 543  WLTCTATNAAGSTVKKAYLT--ISDVPVFV-QLPSHQTLVKGNAITLPCRATAADAP--V 597

Query: 2676 IEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724
            I WFK   +        S        LS  S+   D G+Y C+A N  G
Sbjct: 598  ITWFKADQSGALQQLTSSGVSQANGDLSFASVTRQDRGMYACQACNAAG 646



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 937  GDSTLRVEW-LKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
            GD T  V W L  G     +S  +         L I + T  + G Y C A N++G+ T 
Sbjct: 326  GDPTPSVSWILPSGAIATVTSPASRVQVLANHTLVIGNATESEYGEYVCVAKNSVGEKTR 385

Query: 996  SANLTIVT 1003
               ++I+T
Sbjct: 386  KVTVSILT 393



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 9/97 (9%)

Query: 3709 EGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEY 3768
            +G  V F+C+V  + +P+    W  +G     G++    N     +L I  +   DAG+Y
Sbjct: 40   KGLQVEFECQVSGIANPSYY--WIKDGTNVTKGTQ-DVKNSIS--SLTISGLKFTDAGQY 94

Query: 3769 TCRATNKWGSATTT-AKITCSAKRDIVLESQLPQGMS 3804
             C AT      T+T A +T     DI   +Q P G S
Sbjct: 95   VCVATGIATLTTSTAATLTVQGSPDI---TQGPTGTS 128



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 7/84 (8%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            P F T P + +   EG  + F C    V      + W K G  +      +P       A
Sbjct: 212  PSFTTTPTN-QTAREGSDITFYCMASGVPTPT--ITWHKVGGVILSNRTDKPRPG----A 264

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGT 1527
            + I  +I  D G Y C A+N  GT
Sbjct: 265  IRIQSVIPSDDGSYVCEAINSEGT 288



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 11/82 (13%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P+F     +    QG +AK       NP   +SW+R     +    Y     EQ      
Sbjct: 661 PLFPVPPPDVGVIQGEDAKLMCAPDSNPPATISWSRPDGTALPGTGY-----EQ------ 709

Query: 132 LIKQIGPGDEGEYTCTARNQYG 153
           +I  + P   G+Y C+ARN+YG
Sbjct: 710 VIVGVQPSHVGDYKCSARNEYG 731



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/103 (26%), Positives = 38/103 (36%), Gaps = 7/103 (6%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            +D    P F T   +QT+    + T F C  +  G P   + W   G  +L      P  
Sbjct: 206  LDAPAAPSFTTTPTNQTAREGSDIT-FYCMAS--GVPTPTITWHKVGGVILSNRTDKPRP 262

Query: 4027 DFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
                 A+    V P D G Y+C A N  G       ++  G P
Sbjct: 263  G----AIRIQSVIPSDDGSYVCEAINSEGTKRADVYLRIEGFP 301



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 6/71 (8%)

Query: 1592 GQRAHFERRLIPVSDATLKVEWYHN-NKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTY 1650
            GQ A F    I  ++ +  V W +  ++P+    RFT   N   V  D+      D+G Y
Sbjct: 132  GQEAIFH--CIATANPSPSVSWTNPFDQPINRSGRFTVYGNGSLVISDVKKA---DTGYY 186

Query: 1651 TCRAINALGEA 1661
            TC   N+ G A
Sbjct: 187  TCIVSNSFGSA 197


>SB_43700| Best HMM Match : SRCR (HMM E-Value=0)
          Length = 967

 Score = 79.0 bits (186), Expect = 9e-14
 Identities = 86/343 (25%), Positives = 139/343 (40%), Gaps = 38/343 (11%)

Query: 4480 VFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV--PPSFTLTAQNVNVTSGQLVRLDTKV 4537
            VFA V     G   C+A+     K   G    +  PP  T +    N  +   +R  T V
Sbjct: 462  VFAPVKRTDQGFYTCTASQNAVTKISPGVSLTINFPPDTTFSPVMANQGNSATLRC-TVV 520

Query: 4538 TGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            +G  P   + W+K+G       R  +   +G   L+       D G Y CVA+NS G  R
Sbjct: 521  SGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMGIGR 580

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK--PLPTV 4654
                   S+ A K          N PPE+   L+  + +EG      C ++    P+ + 
Sbjct: 581  -------SIAAAK-------MTVNYPPEV--SLQSIVASEGGLATLRCSVIRSQPPVLSY 624

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR-VTVAAKLKVT 4713
             W K      P+ +  +S T     L  +  +  D+G Y C A NS G  +++A+++ + 
Sbjct: 625  TWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSYTCEASNSVGNGISLASRMTI- 683

Query: 4714 QPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP---TIQWLREG-ALIPET-PDFQ 4768
                  + P +T +  +   EG  A  K  +    +P   +  W++E  +  P T P   
Sbjct: 684  ------HYPPVTSVSPLEAKEGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVS 737

Query: 4769 MIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVET-SAKLVV 4810
              + G +  L+       D G ++C A  +AG     SAKL+V
Sbjct: 738  TANGGRD--LVFSPVDRRDQGMYSCVALGSAGIGRAPSAKLIV 778



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 80/305 (26%), Positives = 117/305 (38%), Gaps = 33/305 (10%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKP--IDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            PP  +L  Q++  + G L  L   V  ++P  +   W K+G    P     +    G   
Sbjct: 592  PPEVSL--QSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRD 649

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            LL    Y  D G Y C A NS G         +SL +      P       P   + PL+
Sbjct: 650  LLFAPVYRTDQGSYTCEASNSVGNG-------ISLASRMTIHYP-------PVTSVSPLE 695

Query: 4631 DKIVAEGQAIEFSCKIV--GKPLPT-VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
             K   EG      C ++  G+P  T   W K  +   P+    +S       L  S    
Sbjct: 696  AK---EGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVSTANGGRDLVFSPVDR 752

Query: 4688 EDEGDYKCVAYNSAGRVTV-AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
             D+G Y CVA  SAG     +AKL V           +TPL    V EG       +  S
Sbjct: 753  RDQGMYSCVALGSAGIGRAPSAKLIVNFEPSV----TVTPL---TVTEGSNVTLVCRTVS 805

Query: 4747 KIK-PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
            + +     WL++G++   +   Q+  E N  +L        D G +TC A  A G   ++
Sbjct: 806  QPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSST 865

Query: 4806 AKLVV 4810
            A L++
Sbjct: 866  AALII 870



 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 79/340 (23%), Positives = 129/340 (37%), Gaps = 34/340 (10%)

Query: 4480 VFAAVAENRGGTAKCSA-NLVVEEKRRQGRGGI-VPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            +FA V     G+  C A N V        R  I  PP  +++           ++    V
Sbjct: 651  LFAPVYRTDQGSYTCEASNSVGNGISLASRMTIHYPPVTSVSPLEAKEGDNATLKCSVLV 710

Query: 4538 TGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEAR 4596
            +G  P   + W+K  +   P  R  +   +G   L+      +D G Y CVA+ SAG  R
Sbjct: 711  SGRPPATSFTWIKESQSFDPATRPSVSTANGGRDLVFSPVDRRDQGMYSCVALGSAGIGR 770

Query: 4597 CDAECVVSLPATKDKPKPQTKAANAPPEI-IEPLKDKIVAEGQAIEFSCKIVGKP-LPTV 4654
                     P+ K          N  P + + PL    V EG  +   C+ V +P +   
Sbjct: 771  A--------PSAK-------LIVNFEPSVTVTPLT---VTEGSNVTLVCRTVSQPEIDRY 812

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
             W K   +   S   Q+++  +   L        D+G+Y C+A+N+ G  +  A L +  
Sbjct: 813  NWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSSTAALIINY 872

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI---QWLREGALIPETPDFQMIH 4771
                   P +         EG     +  + S  +P++    WL++GA I      ++  
Sbjct: 873  R------PTVMVTAQASANEGDGLTLRCTVESS-QPSVGSYTWLKDGAEINLATHPRVRA 925

Query: 4772 EGNNAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVV 4810
            E     L+       D G +TC AT + G      A+L+V
Sbjct: 926  ERGGRDLVFAPVGRADQGNYTCEATNSVGSGTSPPAQLIV 965



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 9/180 (5%)

Query: 402 DVTEGKMTRFDCRV--TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
           +  EG      C V  +GRP      +I + Q  D      +   +G   L+ + V   D
Sbjct: 695 EAKEGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVSTANGGRDLVFSPVDRRD 754

Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP- 518
            G+ +CVA   +G         ++  E  V        + L V EG  V L  R V  P 
Sbjct: 755 QGMYSCVALGSAGIGRAPSAKLIVNFEPSVT------VTPLTVTEGSNVTLVCRTVSQPE 808

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             R  W KDG     +   ++  +     L     + SD   Y C A N  G  ++ A L
Sbjct: 809 IDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSSTAAL 868



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 11/180 (6%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           VTEG      CR   +P  +   ++ D  I +      +  E     L    V  SD G 
Sbjct: 791 VTEGSNVTLVCRTVSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGN 850

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
            TC+A N  G  +    L +  +  V+        +  +  EG+ + L    V +  P +
Sbjct: 851 YTCIAHNAIGGGSSTAALIINYRPTVMVT------AQASANEGDGLTLRC-TVESSQPSV 903

Query: 523 ---TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS-TATRARL 578
              TW KDG  I      R+  + G   L       +D   Y C A N  GS T+  A+L
Sbjct: 904 GSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGNYTCEATNSVGSGTSPPAQL 963



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 43/192 (22%), Positives = 70/192 (36%), Gaps = 9/192 (4%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMV 3106
            PP+  T F  ++  ++G  A    +++     +    W  +G   +++ R       G  
Sbjct: 497  PPD--TTFSPVM-ANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGR 553

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
             L     + TD G YSC A N  G   I   +     +    P  +  +Q+I    +G  
Sbjct: 554  YLVFSSLRRTDQGMYSCVALNSMG---IGRSIAAAKMTVNYPPEVS--LQSIVA-SEGGL 607

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A   C+V+    P +   W  +G     +T        G   L  A     D G Y C A
Sbjct: 608  ATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSYTCEA 667

Query: 3227 YNKYGEDFTRAT 3238
             N  G   + A+
Sbjct: 668  SNSVGNGISLAS 679



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 45/202 (22%), Positives = 77/202 (38%), Gaps = 15/202 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEP-LPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            PP+ +      +  ++   +  V   G P      W +E+     +    + T +    L
Sbjct: 686  PPVTSVSPLEAKEGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVSTANGGRDL 745

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            +   V   D  +++ VA    G  +  SA L+V  +          PS T+T   + VT 
Sbjct: 746  VFSPVDRRDQGMYSCVALGSAGIGRAPSAKLIVNFE----------PSVTVTP--LTVTE 793

Query: 4528 GQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
            G  V L  +      ID Y WLK+G        +++ +E     L  +     D G Y C
Sbjct: 794  GSNVTLVCRTVSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTC 853

Query: 4587 VAINSAGEARCDAECVVSLPAT 4608
            +A N+ G     A  +++   T
Sbjct: 854  IAHNAIGGGSSTAALIINYRPT 875



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 44/172 (25%), Positives = 69/172 (40%), Gaps = 12/172 (6%)

Query: 405 EGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV 463
           +G      C V +GRP      ++ D    D      +   +G   L+ +++  +D G+ 
Sbjct: 509 QGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMY 568

Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI- 522
           +CVA N  G      R     K  V  P  V    ++   EG    L    + +  P + 
Sbjct: 569 SCVALNSMGIG----RSIAAAKMTVNYPPEVS-LQSIVASEGGLATLRCSVIRSQPPVLS 623

Query: 523 -TWQKDGVPIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            TW+KDG+   P  +P + + T GG   L  P    +D   Y C A N  G+
Sbjct: 624 YTWRKDGLTFNPATHPNVSV-THGGRDLLFAP-VYRTDQGSYTCEASNSVGN 673



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 4/73 (5%)

Query: 942  RVEWLKDGR--PVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            R  WLKDG      A S++T   N   +A     V   D G+YTC A+NAIG  +++A L
Sbjct: 811  RYNWLKDGSIFNTSAGSQVTQERNGKLLAFI--GVQRSDQGNYTCIAHNAIGGGSSTAAL 868

Query: 1000 TIVTKKDIIAESQ 1012
             I  +  ++  +Q
Sbjct: 869  IINYRPTVMVTAQ 881



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/83 (28%), Positives = 33/83 (39%)

Query: 2780 LNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY 2839
            L +IV  EG      C+V  S+ P L   W  +       T    +       L     Y
Sbjct: 597  LQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVY 656

Query: 2840 EEDSGIYTCKATNSKGSATTSGS 2862
              D G YTC+A+NS G+  +  S
Sbjct: 657  RTDQGSYTCEASNSVGNGISLAS 679



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 3/111 (2%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P  T TP  L ++E S+    CR +   +   R  W  +G    T +  +   +    +L
Sbjct: 782  PSVTVTP--LTVTEGSNVTLVCRTVSQPEID-RYNWLKDGSIFNTSAGSQVTQERNGKLL 838

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSG 3668
               GV + D G YTC A N  G  + +  L +  R  +++  Q  ++   G
Sbjct: 839  AFIGVQRSDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQASANEGDG 889



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 22/73 (30%), Positives = 30/73 (41%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EGD +   C VE S+       W  +   +   T  +   +     L        D G Y
Sbjct: 886  EGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGNY 945

Query: 2847 TCKATNSKGSATT 2859
            TC+ATNS GS T+
Sbjct: 946  TCEATNSVGSGTS 958



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 23/79 (29%), Positives = 34/79 (43%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            +G    L   V     P     W K+G+   +  R   +   G   L  +SLR  D G+Y
Sbjct: 509  QGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMY 568

Query: 2716 TCKATNLLGEAVSTASIKI 2734
            +C A N +G   S A+ K+
Sbjct: 569  SCVALNSMGIGRSIAAAKM 587



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 1/95 (1%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P  ++EG +    CR    P+ + R  W  +G +  +    + + +     L  + V   
Sbjct: 788  PLTVTEGSNVTLVCRTVSQPEID-RYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRS 846

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQ 1947
            D G YTC A N +G   S+  L +  + +++  +Q
Sbjct: 847  DQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 5/96 (5%)

Query: 1320 IETVEGTNVHLECRL--QPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYP 1377
            +   EG+NV L CR   QP  D   R  W  +G    T    +   E +   L  + V  
Sbjct: 789  LTVTEGSNVTLVCRTVSQPEID---RYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQR 845

Query: 1378 EDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQ 1413
             D G YTC A N +G   ++ AL +  +  +++ +Q
Sbjct: 846  SDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 35/152 (23%), Positives = 58/152 (38%), Gaps = 13/152 (8%)

Query: 4444 WYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
            W ++      S   Q+       +L    V   D   +  +A N  G    +A L++  +
Sbjct: 814  WLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSSTAALIINYR 873

Query: 4504 RRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKP-IDVY-WLKNGKKVQPDIRNK 4561
                      P+  +TAQ  +   G  + L   V  ++P +  Y WLK+G ++      +
Sbjct: 874  ----------PTVMVTAQ-ASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPR 922

Query: 4562 ILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +  E G   L+       D G Y C A NS G
Sbjct: 923  VRAERGGRDLVFAPVGRADQGNYTCEATNSVG 954



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 23/76 (30%), Positives = 31/76 (40%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG    L   V     P L   W K+G+T         +   G   L    +   D G Y
Sbjct: 604  EGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSY 663

Query: 2716 TCKATNLLGEAVSTAS 2731
            TC+A+N +G  +S AS
Sbjct: 664  TCEASNSVGNGISLAS 679



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/74 (29%), Positives = 29/74 (39%)

Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGE 1916
            SEG  A   C +     P +   W  +G           S   G   L    VY  D G 
Sbjct: 603  SEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGS 662

Query: 1917 YTCKAINNLGQAVS 1930
            YTC+A N++G  +S
Sbjct: 663  YTCEASNSVGNGIS 676



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 36/164 (21%), Positives = 60/164 (36%), Gaps = 7/164 (4%)

Query: 3771 RATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPP 3830
            + +  +  AT  +  T +  RD+V      +         L    I  AP  + IV+  P
Sbjct: 723  KESQSFDPATRPSVSTANGGRDLVFSPVDRRDQGMYSCVALGSAGIGRAPSAKLIVNFEP 782

Query: 3831 KFITQIKSHTVEESEGVRFECRV--EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
                 +   TV E   V   CR   +P+ D   R  W ++G +  +    +   +     
Sbjct: 783  S--VTVTPLTVTEGSNVTLVCRTVSQPEID---RYNWLKDGSIFNTSAGSQVTQERNGKL 837

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQ 3932
            L  + V   D G Y C A N  G   + A +     P +++  Q
Sbjct: 838  LAFIGVQRSDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 1/84 (1%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            + EG +V L  +   + + + +  W K+G    T A  + T +     L+   ++  D G
Sbjct: 791  VTEGSNVTLVCRTVSQPEID-RYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQG 849

Query: 2714 IYTCKATNLLGEAVSTASIKIEDR 2737
             YTC A N +G   STA++ I  R
Sbjct: 850  NYTCIAHNAIGGGSSTAALIINYR 873



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/85 (29%), Positives = 33/85 (38%)

Query: 918  QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVH 977
            Q S  EG        +E    S     WLKDG  +  ++        G   L    V   
Sbjct: 881  QASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRA 940

Query: 978  DAGHYTCRAYNAIGQATTSANLTIV 1002
            D G+YTC A N++G  T+     IV
Sbjct: 941  DQGNYTCEATNSVGSGTSPPAQLIV 965



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 42/147 (28%), Positives = 61/147 (41%), Gaps = 13/147 (8%)

Query: 3778 SATTTAKITCSAKRDIVLES--QLPQGM-SGEKIKELERGRISDAPKEEPIVSTPPKFIT 3834
            SAT  +  T +  R +V  S  +  QGM S   +  +  GR   A K    V+ PP+   
Sbjct: 540  SATRPSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMGIGRSIAAAKMT--VNYPPE--V 595

Query: 3835 QIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLL-PSGHRYRTVYDMGFVSLDILY 3893
             ++S    E       C V   + P L   W ++G    P+ H   +V   G    D+L+
Sbjct: 596  SLQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGG---RDLLF 652

Query: 3894 --VYAEDSGEYICRAVNDFGEDFTKAT 3918
              VY  D G Y C A N  G   + A+
Sbjct: 653  APVYRTDQGSYTCEASNSVGNGISLAS 679



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 39/171 (22%), Positives = 61/171 (35%), Gaps = 12/171 (7%)

Query: 403 VTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           + E   T F C VTG+      +W  +        N  +   ++G   L+   V  +D G
Sbjct: 416 LNESTSTTFTCTVTGQSGAFSYSWARDGSPFSLPANIHL---QNGGRDLVFAPVKRTDQG 472

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG--TPT 519
             TC A +++  T     +++     +  P     FS +   +G    L    V    P 
Sbjct: 473 FYTCTA-SQNAVTKISPGVSLT----INFPPDTT-FSPVMANQGNSATLRCTVVSGRPPA 526

Query: 520 PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              TW KDG+         + T  G   L     + +D   Y C A N  G
Sbjct: 527 SSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMG 577



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 7/102 (6%)

Query: 641 VPLKSVTAMEGGKIHFETRIEPVGDPTM-KIEWLKNGQ--SIEASSRFTSIFRFGYISLD 697
           V +  +T  EG  +    R   V  P + +  WLK+G   +  A S+ T   R G + L 
Sbjct: 784 VTVTPLTVTEGSNVTLVCRT--VSQPEIDRYNWLKDGSIFNTSAGSQVTQE-RNGKL-LA 839

Query: 698 MLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQ 739
            + +   D G YTC A +A G   + A L +  R T+  T+Q
Sbjct: 840 FIGVQRSDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 3/95 (3%)

Query: 3705 IDVPEGGPVHFDCRVEPVGDPTM-RIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            + V EG  V   CR   V  P + R +W  +G  F T +      +     L    +   
Sbjct: 789  LTVTEGSNVTLVCRT--VSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRS 846

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
            D G YTC A N  G  ++TA +  + +  +++ +Q
Sbjct: 847  DQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 32/148 (21%), Positives = 49/148 (33%), Gaps = 7/148 (4%)

Query: 3084 WFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDK 3143
            W  +G     S   +        +L  +G + +D G Y+C A N  G    +  L     
Sbjct: 814  WLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGSSTAALII--- 870

Query: 3144 SKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD 3203
                +P  T  +       +G      CTV           W  +G  +  +T  +  ++
Sbjct: 871  --NYRP--TVMVTAQASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAE 926

Query: 3204 FGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
             G   L  A     D G Y C A N  G
Sbjct: 927  RGGRDLVFAPVGRADQGNYTCEATNSVG 954



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 2/86 (2%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P   ++G SA   C +     P     W  +G    S  R   S   G   L   ++   
Sbjct: 504  PVMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRT 563

Query: 1913 DSGEYTCKAINN--LGQAVSSIRLNV 1936
            D G Y+C A+N+  +G+++++ ++ V
Sbjct: 564  DQGMYSCVALNSMGIGRSIAAAKMTV 589



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 3/85 (3%)

Query: 634 YPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY 693
           YPP    V L+S+ A EGG       +     P +   W K+G +   ++        G 
Sbjct: 591 YPPE---VSLQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGG 647

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATG 718
             L    +   D G YTC A ++ G
Sbjct: 648 RDLLFAPVYRTDQGSYTCEASNSVG 672



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 3/90 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP  +++   +I   EGG     C V     P +   W  +G  F   +  +     G  
Sbjct: 592  PPEVSLQ---SIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGR 648

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
             L    +Y  D G YTC A+N  G+  + A
Sbjct: 649  DLLFAPVYRTDQGSYTCEASNSVGNGISLA 678



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPS-RDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            ++ ++ +  KEGDN   +C+V  S R P     W   ++     TR   +       L  
Sbjct: 688  VTSVSPLEAKEGDNATLKCSVLVSGRPPATSFTWIKESQSFDPATRPSVSTANGGRDLVF 747

Query: 2836 THTYEEDSGIYTCKATNSKG 2855
            +     D G+Y+C A  S G
Sbjct: 748  SPVDRRDQGMYSCVALGSAG 767



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/81 (25%), Positives = 31/81 (38%)

Query: 2115 LTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYT 2174
            +T+  +  EGD     C VE       +  W  +G +I      R   + G   L     
Sbjct: 878  VTAQASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPV 937

Query: 2175 YAEDSGTYMCKATNKLGEAVN 2195
               D G Y C+ATN +G   +
Sbjct: 938  GRADQGNYTCEATNSVGSGTS 958



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 2/105 (1%)

Query: 625 IPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSR 684
           I PG    +  PP        V A +G        +     P     W+K+G   ++++R
Sbjct: 486 ISPGVSLTINFPPD--TTFSPVMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATR 543

Query: 685 FTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT 729
            +     G   L   SL   D G Y+C A+++ G+  + A   +T
Sbjct: 544 PSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMGIGRSIAAAKMT 588



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/76 (26%), Positives = 29/76 (38%)

Query: 3434 EGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEY 3493
            EG  A     +  +  P L   W  +G +    +        G   L  +P Y  D G Y
Sbjct: 604  EGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSY 663

Query: 3494 LCRAYNNYGEAVTTAS 3509
             C A N+ G  ++ AS
Sbjct: 664  TCEASNSVGNGISLAS 679



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 3/96 (3%)

Query: 1186 PPPVSEGKNIHLECRLEPMGDPTM-RVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244
            P  V+EG N+ L CR   +  P + R  W  +G      +  +   +     L  I    
Sbjct: 788  PLTVTEGSNVTLVCRT--VSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQR 845

Query: 1245 ADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280
            +D G YT  A N +G   ++A + +  R  ++   Q
Sbjct: 846  SDQGNYTCIAHNAIGGGSSTAALIINYRPTVMVTAQ 881



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 5/75 (6%)

Query: 797 VSDPTM-RVEWYKDGRPI--TASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGE 853
           VS P + R  W KDG     +A S++T   N G + L  + ++  D G+YT  A N +G 
Sbjct: 804 VSQPEIDRYNWLKDGSIFNTSAGSQVTQERN-GKL-LAFIGVQRSDQGNYTCIAHNAIGG 861

Query: 854 AISTASIRVAARSTV 868
             STA++ +  R TV
Sbjct: 862 GSSTAALIINYRPTV 876



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/76 (28%), Positives = 28/76 (36%)

Query: 784 EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSY 843
           EG  A     +     P +   W KDG     ++        G   L    +   D GSY
Sbjct: 604 EGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSY 663

Query: 844 TVRAVNKLGEAISTAS 859
           T  A N +G  IS AS
Sbjct: 664 TCEASNSVGNGISLAS 679



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 16/69 (23%), Positives = 32/69 (46%)

Query: 2390 EGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVY 2449
            +G +A   C ++    P     W ++    + ++R + +   G   +  S +R  D+G+Y
Sbjct: 509  QGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMY 568

Query: 2450 MCRASNLLG 2458
             C A N +G
Sbjct: 569  SCVALNSMG 577



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 2/105 (1%)

Query: 52  VESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAP 111
           + S G  + I A +     PP  E   ++   ++GG A     +  +  PV+S+T +K  
Sbjct: 573 LNSMGIGRSIAAAKMTVNYPP--EVSLQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDG 630

Query: 112 LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           L          +   G   LL   +   D+G YTC A N  G  I
Sbjct: 631 LTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSYTCEASNSVGNGI 675



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/80 (27%), Positives = 29/80 (36%)

Query: 919 ISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHD 978
           I   EGG A     +       L   W KDG     ++        G   L    V   D
Sbjct: 600 IVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTD 659

Query: 979 AGHYTCRAYNAIGQATTSAN 998
            G YTC A N++G   + A+
Sbjct: 660 QGSYTCEASNSVGNGISLAS 679



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 19/68 (27%), Positives = 28/68 (41%), Gaps = 1/68 (1%)

Query: 279 EGADAQFQVQLSGNPR-PRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337
           EG++     +    P   R  W K+G     S   ++    N   L     Q+SD G+YT
Sbjct: 793 EGSNVTLVCRTVSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYT 852

Query: 338 LLAENPNG 345
            +A N  G
Sbjct: 853 CIAHNAIG 860



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNA--IGQATTSANLTIV 1002
            W+KDG   ++++R +     G   L   S+   D G Y+C A N+  IG++  +A +T+ 
Sbjct: 531  WMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTDQGMYSCVALNSMGIGRSIAAAKMTVN 590

Query: 1003 TKKDIIAES--QHPGGLEKIQ 1021
               ++  +S     GGL  ++
Sbjct: 591  YPPEVSLQSIVASEGGLATLR 611



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PP+ T +P  ++ ++ +SA   C ++     +    W  +G    + +R       G   
Sbjct: 497  PPDTTFSP--VMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRY 554

Query: 3617 LEIGGVYQRDAGLYTCKATNRHG 3639
            L    + + D G+Y+C A N  G
Sbjct: 555  LVFSSLRRTDQGMYSCVALNSMG 577



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/84 (22%), Positives = 32/84 (38%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            ++  +G++    C V   R P     W  +     S TR   +       L  +     D
Sbjct: 505  VMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLVFSSLRRTD 564

Query: 2843 SGIYTCKATNSKGSATTSGSLRCT 2866
             G+Y+C A NS G   +  + + T
Sbjct: 565  QGMYSCVALNSMGIGRSIAAAKMT 588



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 2/83 (2%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            PPE +     ++ SE   A   C +I      +   W  +G      +        G   
Sbjct: 592  PPEVSL--QSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRD 649

Query: 3617 LEIGGVYQRDAGLYTCKATNRHG 3639
            L    VY+ D G YTC+A+N  G
Sbjct: 650  LLFAPVYRTDQGSYTCEASNSVG 672



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/85 (23%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 1984 IKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYA- 2042
            +++   +EG    L  ++     P +   W  +G           +   G    D+L+A 
Sbjct: 597  LQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHG--GRDLLFAP 654

Query: 2043 -YAEDTGTYMCKATNAVGEAVTTSS 2066
             Y  D G+Y C+A+N+VG  ++ +S
Sbjct: 655  VYRTDQGSYTCEASNSVGNGISLAS 679



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/73 (26%), Positives = 28/73 (38%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            EG  A   C V     P L+  W  +G           +   G   L     Y  D G+Y
Sbjct: 604  EGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATHPNVSVTHGGRDLLFAPVYRTDQGSY 663

Query: 2183 MCKATNKLGEAVN 2195
             C+A+N +G  ++
Sbjct: 664  TCEASNSVGNGIS 676



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/86 (26%), Positives = 30/86 (34%)

Query: 3696 RFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIAL 3755
            R TV +       EG  +   C VE          W  +G      +      + G   L
Sbjct: 873  RPTVMVTAQASANEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDL 932

Query: 3756 DIDYIYARDAGEYTCRATNKWGSATT 3781
                +   D G YTC ATN  GS T+
Sbjct: 933  VFAPVGRADQGNYTCEATNSVGSGTS 958



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/73 (27%), Positives = 28/73 (38%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  + L   VE          W K+G  +      +   + G   L    +   D G Y
Sbjct: 886  EGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGNY 945

Query: 2716 TCKATNLLGEAVS 2728
            TC+ATN +G   S
Sbjct: 946  TCEATNSVGSGTS 958



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/102 (22%), Positives = 41/102 (40%), Gaps = 2/102 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP     P  +     A  +  V     P    TW K+G    ++ +  + TT+    L 
Sbjct: 497 PPDTTFSPVMANQGNSATLRCTVVSGRPPASSFTWMKDGLFFDSATRPSVSTTNGGRYLV 556

Query: 325 VRNTQKSDSGHYTLLAENPNGC--IVTSGYLAVESPTESYVQ 364
             + +++D G Y+ +A N  G    + +  + V  P E  +Q
Sbjct: 557 FSSLRRTDQGMYSCVALNSMGIGRSIAAAKMTVNYPPEVSLQ 598



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 6/94 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV   P+ S  L +I   EG    L C +       +   W  +G          P   
Sbjct: 587  MTVNYPPEVS--LQSIVASEGGLATLRCSVIRSQPPVLSYTWRKDGLTFNPATH--PNVS 642

Query: 1365 FDYVALDLL--SVYPEDSGVYTCQATNQLGEAVT 1396
              +   DLL   VY  D G YTC+A+N +G  ++
Sbjct: 643  VTHGGRDLLFAPVYRTDQGSYTCEASNSVGNGIS 676



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/78 (24%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 1737 VGDPKL-RVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            V  P++ R  WL++G     S       +     L    V   D G YTC A N +G   
Sbjct: 804  VSQPEIDRYNWLKDGSIFNTSAGSQVTQERNGKLLAFIGVQRSDQGNYTCIAHNAIGGGS 863

Query: 1796 TSSTLFVQSKASLQLESQ 1813
            +++ L +  + ++ + +Q
Sbjct: 864  STAALIINYRPTVMVTAQ 881



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/71 (25%), Positives = 28/71 (39%)

Query: 1190 SEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGE 1249
            +EG  + L C +E          W  +G  + + +  +   + G   L       AD G 
Sbjct: 885  NEGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGN 944

Query: 1250 YTVRAVNHLGS 1260
            YT  A N +GS
Sbjct: 945  YTCEATNSVGS 955



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/70 (28%), Positives = 28/70 (40%)

Query: 1458 EGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIY 1517
            EG  +   C +E    S     W K+G  + +    R   + G   L    +   D G Y
Sbjct: 886  EGDGLTLRCTVESSQPSVGSYTWLKDGAEINLATHPRVRAERGGRDLVFAPVGRADQGNY 945

Query: 1518 TCRAVNLVGT 1527
            TC A N VG+
Sbjct: 946  TCEATNSVGS 955


>SB_41825| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 825

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 13/204 (6%)

Query: 376 QRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIR-D 434
           Q   + R+E+ E    P   +   D  V  G + +  C  TG P P ++W + D + +  
Sbjct: 389 QFSKKARLEVLE---FPVLTRKPHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFP 445

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
               K + +    H  +I N    D+G  TC A N +G       + V+E      P+F+
Sbjct: 446 AAEEKRIEHLPSEHLFIIRNARGVDTGAYTCTATNGAGSINATAYVTVLE-----VPRFM 500

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
           +   +  VR GE  VL  +A G+P PR TW KD   +  +  +  H       L      
Sbjct: 501 QSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVTLSARVVAH----GQLLVFVTVL 556

Query: 555 ASDAAWYQCTAQNVAGSTATRARL 578
             D   Y C   N  G+     RL
Sbjct: 557 PGDEGTYTCQVSNSLGTARQNTRL 580



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 55/203 (27%), Positives = 75/203 (36%), Gaps = 22/203 (10%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW-LKNGKKVQPDIRNKILEE-DGTYTL 4571
            P  T    +V+V  G L++L    TG     + W + +GK   P    K +E     +  
Sbjct: 402  PVLTRKPHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLF 461

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
            +I  A   D+G Y C A N AG     A   V                   P  ++ +  
Sbjct: 462  IIRNARGVDTGAYTCTATNGAGSINATAYVTVL----------------EVPRFMQSMVS 505

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            K V  G++    CK  G P+P   WYK DK +  S        A    L      P DEG
Sbjct: 506  KRVRTGESAVLECKASGSPMPRFTWYKDDKKVTLSARV----VAHGQLLVFVTVLPGDEG 561

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQ 4714
             Y C   NS G      +L V +
Sbjct: 562  TYTCQVSNSLGTARQNTRLTVVE 584



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 53/242 (21%), Positives = 96/242 (39%), Gaps = 26/242 (10%)

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L ++     D+G Y+C+A N  G              ++   K + +    P    +P  
Sbjct: 365  LFLISVDFSDAGLYQCIASNKYG--------------SQFSKKARLEVLEFPVLTRKP-H 409

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK--PSKYFQMSRTADEYTLRISEAFPE 4688
            D  V  G  I+  C   G P+P + W  GD   K   ++  ++     E+   I  A   
Sbjct: 410  DVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNARGV 469

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            D G Y C A N AG +   A + V +  +   + ++   R   V  G+ A  + + +   
Sbjct: 470  DTGAYTCTATNGAGSINATAYVTVLEVPRF--MQSMVSKR---VRTGESAVLECKASGSP 524

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
             P   W ++   +  T   +++  G   +L+       D GT+TC+ + + G    + +L
Sbjct: 525  MPRFTWYKDDKKV--TLSARVVAHGQ--LLVFVTVLPGDEGTYTCQVSNSLGTARQNTRL 580

Query: 4809 VV 4810
             V
Sbjct: 581  TV 582



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 42/128 (32%), Positives = 58/128 (45%), Gaps = 8/128 (6%)

Query: 447 NHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
           N  L + +V  SD+G+  C+A NK G + + + RL V+E      P    +   ++V  G
Sbjct: 362 NSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLE-----FPVLTRKPHDVSVHVG 416

Query: 506 EPVVLNARAVGTPTPRITWQK-DGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQC 563
             + L   A G P P I+W+  DG    P   E RI          I  A+  D   Y C
Sbjct: 417 GLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNARGVDTGAYTC 476

Query: 564 TAQNVAGS 571
           TA N AGS
Sbjct: 477 TATNGAGS 484



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 48/197 (24%), Positives = 77/197 (39%), Gaps = 20/197 (10%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWY----RENFPIKNSPDFQIHTFSTKS 4466
            P+ T+K     V      +      G P+P+I W     +  FP   + + +I    ++ 
Sbjct: 402  PVLTRKPHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPA--AEEKRIEHLPSEH 459

Query: 4467 ILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVT 4526
            + IIR     D+  +   A N  G+   +A + V E           P F  +  +  V 
Sbjct: 460  LFIIRNARGVDTGAYTCTATNGAGSINATAYVTVLEV----------PRFMQSMVSKRVR 509

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
            +G+   L+ K +G+      W K+ KKV    R   +   G   L+ +   P D G Y C
Sbjct: 510  TGESAVLECKASGSPMPRFTWYKDDKKVTLSAR---VVAHGQL-LVFVTVLPGDEGTYTC 565

Query: 4587 VAINSAGEARCDAECVV 4603
               NS G AR +    V
Sbjct: 566  QVSNSLGTARQNTRLTV 582



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 54/207 (26%), Positives = 91/207 (43%), Gaps = 22/207 (10%)

Query: 4619 ANAPPEI-IEPLKDKIVAEGQAIEFSCKI--VGKPLPTV--QWYKGDKLIKPSKYFQMSR 4673
            +N  P+I + P   K +  G  +   C++  V +   +V  QW  G ++I         R
Sbjct: 294  SNPIPQISVHPPSQKAM-RGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITDFVR 352

Query: 4674 TADEYTLRI-SEAFP-----EDEGDYKCVAYNSAG-RVTVAAKLKVTQPDQADNLPALTP 4726
            T D+  +   S+ F       D G Y+C+A N  G + +  A+L+V +       P LT 
Sbjct: 353  TDDDDIVTYNSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLE------FPVLTR 406

Query: 4727 L-RDIVVYEGQPAQFKTQITSKIKPTIQW-LREG-ALIPETPDFQMIHEGNNAVLLIGNT 4783
               D+ V+ G   +     T    P I W + +G +  P   + ++ H  +  + +I N 
Sbjct: 407  KPHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNA 466

Query: 4784 YEEDTGTFTCRATTAAGQVETSAKLVV 4810
               DTG +TC AT  AG +  +A + V
Sbjct: 467  RGVDTGAYTCTATNGAGSINATAYVTV 493



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 6/99 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV++ P+F +++ +     G +  LEC+    G    R  W+ + K +    R     +
Sbjct: 491  VTVLEVPRFMQSMVSKRVRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVVAHGQ 548

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
                 L  ++V P D G YTCQ +N LG A  +  L V+
Sbjct: 549  L----LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTVV 583



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+F++    + V  G+    +C+ +G P P  TW+ +D+++    + +++ +      L+
Sbjct: 497 PRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVT--LSARVVAH---GQLLV 551

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE 484
              V   D G  TC   N  G      RL V+E
Sbjct: 552 FVTVLPGDEGTYTCQVSNSLGTARQNTRLTVVE 584



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 7/99 (7%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V V + PRF+  +    ++  G+SA  EC+    P P  R  WY + K +    R     
Sbjct: 491  VTVLEVPRFMQSMVSK-RVRTGESAVLECKASGSPMP--RFTWYKDDKKVTLSARVVAHG 547

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
                  L  +TV   D G YTC+  N+LG A  + RL V
Sbjct: 548  QL----LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTV 582



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 7/95 (7%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+Q + +   V  G++  LEC+    G P  R  W+ + + VT+ +R   +       
Sbjct: 497  PRFMQSMVSKR-VRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVVAHGQL---- 549

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIE 1271
            L  +     D G YT +  N LG+A  +  + V+E
Sbjct: 550  LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTVVE 584



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 6/96 (6%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P F   M   RV   ++A  E +    G P  R  W ++   +  S R+       
Sbjct: 493  VLEVPRFMQSMVSKRVRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVVAHGQL- 549

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
               L    V P D GTYTC+  N LG A  ++ L V
Sbjct: 550  ---LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTV 582



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 6/84 (7%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P F Q   + R   G +A  E K  G+P P  +W +      +  K ++          L
Sbjct: 497 PRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYK------DDKKVTLSARVVAHGQLL 550

Query: 132 LIKQIGPGDEGEYTCTARNQYGEA 155
           +   + PGDEG YTC   N  G A
Sbjct: 551 VFVTVLPGDEGTYTCQVSNSLGTA 574



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 4/80 (5%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+  Q   + +++ G  A  + + SG+P PR TW+K+ +++  S +   +  H    + V
Sbjct: 497 PRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVTLSAR---VVAHGQLLVFV 553

Query: 326 RNTQKSDSGHYTLLAENPNG 345
                 D G YT    N  G
Sbjct: 554 -TVLPGDEGTYTCQVSNSLG 572



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 7/83 (8%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F Q + +   ++ G++A  +C+    G P  +  W++++K +  S+R+   H    V 
Sbjct: 497  PRFMQSMVS-KRVRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVV-AHGQLLVF 552

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            +T   V   DEG Y C+ SN LG
Sbjct: 553  VT---VLPGDEGTYTCQVSNSLG 572



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 16/169 (9%)

Query: 3075 TGDQSMVIEW-FYNGKT-IEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQA 3132
            TG    VI W   +GK+   A+   R  +     +  I   +  D+G Y+C ATN  G  
Sbjct: 426  TGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNARGVDTGAYTCTATNGAGSI 485

Query: 3133 EISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM 3192
              +  +  +     + PRF   + + + ++ G+SA  EC       P  +  WY + + +
Sbjct: 486  NATAYVTVL-----EVPRFMQSMVS-KRVRTGESAVLECKA--SGSPMPRFTWYKDDKKV 537

Query: 3193 RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG--EDFTRATI 3239
              S R+      G +++ +      D G Y C+  N  G     TR T+
Sbjct: 538  TLSARVVA---HGQLLVFVTVLPG-DEGTYTCQVSNSLGTARQNTRLTV 582



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 7/102 (6%)

Query: 2903 VPDTEYPKPEWII-PIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQG--SR 2959
            V DT  P P+  + P + +    +   L    QV  +N   ++++W    +V+ +   + 
Sbjct: 290  VCDTSNPIPQISVHPPSQKAMRGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITD 349

Query: 2960 FKLTSDFGFVT----LDLVDVYERDSGIYTCKAYNKRGEAFT 2997
            F  T D   VT    L L+ V   D+G+Y C A NK G  F+
Sbjct: 350  FVRTDDDDIVTYNSDLFLISVDFSDAGLYQCIASNKYGSQFS 391



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 4/92 (4%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P F + M   RV   E A  E +  G P+P   WY+++  +  S     H      +L+ 
Sbjct: 497  PRFMQSMVSKRVRTGESAVLECKASGSPMPRFTWYKDDKKVTLSARVVAH----GQLLVF 552

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
              V   D   +     N  GTA+ +  L V E
Sbjct: 553  VTVLPGDEGTYTCQVSNSLGTARQNTRLTVVE 584



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 4/66 (6%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G    R  W KD + V  S+R+          L   +V   D G YTC+  N++G A  +
Sbjct: 522  GSPMPRFTWYKDDKKVTLSARVVAHGQL----LVFVTVLPGDEGTYTCQVSNSLGTARQN 577

Query: 997  ANLTIV 1002
              LT+V
Sbjct: 578  TRLTVV 583



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 3/146 (2%)

Query: 213 TDHSSTDDFKVDTFEYRL-LREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQK 271
           TD   TDD  + T+   L L  V F ++   + +  +           L  +  P + +K
Sbjct: 348 TDFVRTDDDDIVTYNSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTRK 407

Query: 272 PRNSKLQEGADAQFQVQLSGNPRPRVTW-FKNGQ-RLINSNKHEIITTHNHTTLRVRNTQ 329
           P +  +  G   +     +G P P ++W   +G+ +   + +  I    +     +RN +
Sbjct: 408 PHDVSVHVGGLIKLPCAATGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNAR 467

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAV 355
             D+G YT  A N  G I  + Y+ V
Sbjct: 468 GVDTGAYTCTATNGAGSINATAYVTV 493



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 7/93 (7%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+ ++ S + ++ G+ A  EC+      P  T  W+ + +K+    R    H    V 
Sbjct: 497  PRFMQSMVS-KRVRTGESAVLECKASGSPMPRFT--WYKDDKKVTLSARV-VAHGQLLVF 552

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            + +L     D GTY C+ +N LG A     L V
Sbjct: 553  VTVL---PGDEGTYTCQVSNSLGTARQNTRLTV 582



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 7/93 (7%)

Query: 770 PQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVS 829
           P+F++ +     ++ G +A  E + +    P  R  WYKD + +T S+R+ +    G + 
Sbjct: 497 PRFMQSMVSK-RVRTGESAVLECKAS--GSPMPRFTWYKDDKKVTLSARVVA---HGQLL 550

Query: 830 LNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
           + +  L   D G+YT +  N LG A     + V
Sbjct: 551 VFVTVLPG-DEGTYTCQVSNSLGTARQNTRLTV 582



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 8/80 (10%)

Query: 86  GGNAKFEGKLRGNPTPVVSWT----RKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDE 141
           GG  K      G P PV+SW     + K P  E      R      +   +I+     D 
Sbjct: 416 GGLIKLPCAATGYPVPVISWRMGDGKSKFPAAE----EKRIEHLPSEHLFIIRNARGVDT 471

Query: 142 GEYTCTARNQYGEAICSVYI 161
           G YTCTA N  G    + Y+
Sbjct: 472 GAYTCTATNGAGSINATAYV 491



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 7/92 (7%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PRF+    S + V  G+    ECK         +  W+K+ + VT+  R   +   G + 
Sbjct: 497  PRFMQSMVS-KRVRTGESAVLECKASG--SPMPRFTWYKDDKKVTLSAR---VVAHGQL- 549

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            L  + ++  D G YTC+  N +GT   + RLT
Sbjct: 550  LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLT 581



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 7/99 (7%)

Query: 1037 VKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYH 1096
            V + + PRF+  +  + ++  G+SA  E +         T  WY + K++T + R+  + 
Sbjct: 491  VTVLEVPRFMQSMV-SKRVRTGESAVLECKASGSPMPRFT--WYKDDKKVTLSARVVAHG 547

Query: 1097 DFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV 1135
                  L   +V   D G YT    N+ G A+ +  +TV
Sbjct: 548  QL----LVFVTVLPGDEGTYTCQVSNSLGTARQNTRLTV 582



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 4/49 (8%)

Query: 1613 WYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            WY ++K +   +R           L  ++ LP D GTYTC+  N+LG A
Sbjct: 530  WYKDDKKVTLSARVVAHGQL----LVFVTVLPGDEGTYTCQVSNSLGTA 574



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 8/112 (7%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPV--GDQTMRVEWFCNGKPIKTGH--RFRPAYEFD 1366
            PQ S    + + + G NV L CR+Q V     ++R++W    + I       F    + D
Sbjct: 298  PQISVHPPSQKAMRGDNVTLRCRVQVVQRNSSSVRLQWRLGYEVISERDITDFVRTDDDD 357

Query: 1367 YVA----LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQH 1414
             V     L L+SV   D+G+Y C A+N+ G   +  A   + +  ++    H
Sbjct: 358  IVTYNSDLFLISVDFSDAGLYQCIASNKYGSQFSKKARLEVLEFPVLTRKPH 409



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 10/88 (11%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDW-FHNGR---PFATGSRV-HTLNDFGFIALDID 3758
            ++ V  GG +   C     G P   I W   +G+   P A   R+ H  ++  FI  +  
Sbjct: 410  DVSVHVGGLIKLPCAA--TGYPVPVISWRMGDGKSKFPAAEEKRIEHLPSEHLFIIRNAR 467

Query: 3759 YIYARDAGEYTCRATNKWGSATTTAKIT 3786
             +   D G YTC ATN  GS   TA +T
Sbjct: 468  GV---DTGAYTCTATNGAGSINATAYVT 492


>SB_40708| Best HMM Match : SRCR (HMM E-Value=0)
          Length = 1976

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 80/321 (24%), Positives = 122/321 (38%), Gaps = 41/321 (12%)

Query: 4440 PLIK-WYRENFPIKNSPDFQIH-TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P+I  W ++  PI  +    +  T  T   L++  V   D   +  V +N  G+   S  
Sbjct: 1672 PIISDWLKDGKPIDENDVKSLRITTDTSGQLVVNNVQRSDFGNYTCVLKNSAGSISASTI 1731

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V E  R     +V  S +L A+      GQ   +   ++     ++ W +NG  ++  
Sbjct: 1732 VTVNEAPR-----VVDFSPSLLAK------GQTAYIYCNISSYPTANITWKRNGAVLKGP 1780

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
              N        +TL I  A  +DSG+YEC A N  G A  +    V +P++         
Sbjct: 1781 RYNVFTNN---FTLAIYNAVFEDSGQYECTAQNWLGTASANVSVSVGMPSS--------- 1828

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
             A AP +        +V   Q +   C   G+P P V W K    IK       +R  + 
Sbjct: 1829 IATAPSK-------TVVNPSQRVTLKCNATGQPQPVVTWKKDGVTIKTGP----NRVVEP 1877

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
             TL I      D G Y C+A N     TV + + V+ P   +      P ++I V  G  
Sbjct: 1878 GTLTIGVVSRADTGMYACIAQNPQNIATVFSSVIVSGPPIINR-----PPQNISVLTGAN 1932

Query: 4738 AQFKTQITSKIKPTIQWLREG 4758
              F  Q      P   W   G
Sbjct: 1933 VSFLCQAMGSPPPVFTWYHNG 1953



 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 53/188 (28%), Positives = 90/188 (47%), Gaps = 12/188 (6%)

Query: 389  ALAPQF-VKVCQDRDVTEGKMTRFDCR-VTGRPYPEVTWFINDRQIRDDYNHKIL-VNES 445
            ++AP+F V+   +   T     R  CR V     P ++ ++ D +  D+ + K L +   
Sbjct: 1638 SIAPEFQVQPANNITTTTESAFRIGCRSVPPVVTPIISDWLKDGKPIDENDVKSLRITTD 1697

Query: 446  GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
             +  L++ NV  SD G  TCV +N +G  +    + V E     AP+ V+ FS   + +G
Sbjct: 1698 TSGQLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTVNE-----APRVVD-FSPSLLAKG 1751

Query: 506  EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
            +   +       PT  ITW+++G  ++  P   + T+    TL I  A   D+  Y+CTA
Sbjct: 1752 QTAYIYCNISSYPTANITWKRNGA-VLKGPRYNVFTNN--FTLAIYNAVFEDSGQYECTA 1808

Query: 566  QNVAGSTA 573
            QN  G+ +
Sbjct: 1809 QNWLGTAS 1816



 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 42/106 (39%), Positives = 59/106 (55%), Gaps = 9/106 (8%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT-S 1896
            V VN+APR +     P+ L++GQ+A+  C I  YP  N  + W  NG VL+ G RY   +
Sbjct: 1732 VTVNEAPRVVDF--SPSLLAKGQTAYIYCNISSYPTAN--ITWKRNGAVLK-GPRYNVFT 1786

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESI 1942
            N+F  A   I     EDSG+Y C A N LG A +++ ++V    SI
Sbjct: 1787 NNFTLA---IYNAVFEDSGQYECTAQNWLGTASANVSVSVGMPSSI 1829



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 48/166 (28%), Positives = 68/166 (40%), Gaps = 15/166 (9%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            + +G+     C ++  P   +TW  N   ++    + +  N   N  L I N    DSG 
Sbjct: 1748 LAKGQTAYIYCNISSYPTANITWKRNGAVLKGP-RYNVFTN---NFTLAIYNAVFEDSGQ 1803

Query: 463  VTCVARNKSGETAFQCRLNV-IEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
              C A+N  G  +    ++V +      AP      S   V   + V L   A G P P 
Sbjct: 1804 YECTAQNWLGTASANVSVSVGMPSSIATAP------SKTVVNPSQRVTLKCNATGQPQPV 1857

Query: 522  ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
            +TW+KDGV I   P  R+   G   TL I     +D   Y C AQN
Sbjct: 1858 VTWKKDGVTIKTGPN-RVVEPG---TLTIGVVSRADTGMYACIAQN 1899



 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 63/224 (28%), Positives = 90/224 (40%), Gaps = 33/224 (14%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P   I W R    +K  P + + T +  ++ I   VF EDS  +   A+N  GTA  SAN
Sbjct: 1764 PTANITWKRNGAVLKG-PRYNVFT-NNFTLAIYNAVF-EDSGQYECTAQNWLGTA--SAN 1818

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD 4557
            + V           +P S         V   Q V L    TG     V W K+G  ++  
Sbjct: 1819 VSVSVG--------MPSSIATAPSKTVVNPSQRVTLKCNATGQPQPVVTWKKDGVTIKTG 1870

Query: 4558 IRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
              N+++E  GT T+ ++     D+G Y C+A N    A   +  +VS P           
Sbjct: 1871 -PNRVVEP-GTLTIGVVSR--ADTGMYACIAQNPQNIATVFSSVIVSGPPI--------- 1917

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
              N PP+ I       V  G  + F C+ +G P P   WY   K
Sbjct: 1918 -INRPPQNIS------VLTGANVSFLCQAMGSPPPVFTWYHNGK 1954



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 14/197 (7%)

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV--QWYKGDKLIKPSKYFQMSRTA 4675
            A+ AP   ++P  +       A    C+ V   +  +   W K  K I  +    +  T 
Sbjct: 1637 ASIAPEFQVQPANNITTTTESAFRIGCRSVPPVVTPIISDWLKDGKPIDENDVKSLRITT 1696

Query: 4676 DEY-TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ-PDQADNLPALTPLRDIVVY 4733
            D    L ++     D G+Y CV  NSAG ++ +  + V + P   D  P+L       + 
Sbjct: 1697 DTSGQLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTVNEAPRVVDFSPSL-------LA 1749

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +GQ A     I+S     I W R GA++ + P + +    NN  L I N   ED+G + C
Sbjct: 1750 KGQTAYIYCNISSYPTANITWKRNGAVL-KGPRYNVFT--NNFTLAIYNAVFEDSGQYEC 1806

Query: 4794 RATTAAGQVETSAKLVV 4810
             A    G    +  + V
Sbjct: 1807 TAQNWLGTASANVSVSV 1823



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 52/261 (19%), Positives = 97/261 (37%), Gaps = 18/261 (6%)

Query: 100  TPVVS-WTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
            TP++S W +   P+ E +  S+R    T    L++  +   D G YTC  +N  G    S
Sbjct: 1671 TPIISDWLKDGKPIDENDVKSLRITTDTSG-QLVVNNVQRSDFGNYTCVLKNSAGSISAS 1729

Query: 159  VYIQP-EGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSS 217
              +   E               +         +Y T   T +++    K    N      
Sbjct: 1730 TIVTVNEAPRVVDFSPSLLAKGQTAYIYCNISSYPTANITWKRNGAVLKGPRYN----VF 1785

Query: 218  TDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL 277
            T++F +  +   +  +    E   + ++G +   +S  +        P  IA  P  + +
Sbjct: 1786 TNNFTLAIYN-AVFEDSGQYECTAQNWLGTASANVSVSVGM------PSSIATAPSKTVV 1838

Query: 278  QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYT 337
                    +   +G P+P VTW K+G   I +  + ++      TL +    ++D+G Y 
Sbjct: 1839 NPSQRVTLKCNATGQPQPVVTWKKDGV-TIKTGPNRVV---EPGTLTIGVVSRADTGMYA 1894

Query: 338  LLAENPNGCIVTSGYLAVESP 358
             +A+NP         + V  P
Sbjct: 1895 CIAQNPQNIATVFSSVIVSGP 1915



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 54/227 (23%), Positives = 86/227 (37%), Gaps = 15/227 (6%)

Query: 78   FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIG 137
            F  +  A+G  A     +   PT  ++W R  A L        RYN  T + +L I    
Sbjct: 1743 FSPSLLAKGQTAYIYCNISSYPTANITWKRNGAVLK-----GPRYNVFTNNFTLAIYNAV 1797

Query: 138  PGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYT 197
              D G+Y CTA+N  G A  S  +                   + S+ V  K   T    
Sbjct: 1798 FEDSGQYECTAQNWLGTA--SANVSVSVGMPSSIATAPSKTVVNPSQRVTLKCNATGQPQ 1855

Query: 198  TEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEID 257
               + +   V    G +       +V       +  VS  ++     + ++   I+T + 
Sbjct: 1856 PVVTWKKDGVTIKTGPN-------RVVEPGTLTIGVVSRADTGMYACIAQNPQNIAT-VF 1907

Query: 258  RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
             S+    PP I + P+N  +  GA+  F  Q  G+P P  TW+ NG+
Sbjct: 1908 SSVIVSGPPIINRPPQNISVLTGANVSFLCQAMGSPPPVFTWYHNGK 1954



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 14/128 (10%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V   +     C  TG+P P VTW  +   I+   N  +   E G   L I  V+ +D+G+
Sbjct: 1838 VNPSQRVTLKCNATGQPQPVVTWKKDGVTIKTGPNRVV---EPGT--LTIGVVSRADTGM 1892

Query: 463  VTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEPVVLNARAVGTPTP 520
              C+A+N     T F    +VI    V  P  + R    ++V  G  V    +A+G+P P
Sbjct: 1893 YACIAQNPQNIATVFS---SVI----VSGPPIINRPPQNISVLTGANVSFLCQAMGSPPP 1945

Query: 521  RITWQKDG 528
              TW  +G
Sbjct: 1946 VFTWYHNG 1953



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/123 (24%), Positives = 56/123 (45%), Gaps = 14/123 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G+P P++ W ++   IK  P+  +    T +I ++ +    D+ ++A +A+N    A   
Sbjct: 1852 GQPQPVVTWKKDGVTIKTGPNRVVEP-GTLTIGVVSRA---DTGMYACIAQNPQNIATVF 1907

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
            ++++V            PP      QN++V +G  V    +  G+ P    W  NGK+  
Sbjct: 1908 SSVIVSG----------PPIINRPPQNISVLTGANVSFLCQAMGSPPPVFTWYHNGKEKN 1957

Query: 4556 PDI 4558
             DI
Sbjct: 1958 KDI 1960



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 5/105 (4%)

Query: 275  SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSG 334
            S L +G  A     +S  P   +TW +NG  ++   ++ + T  N+ TL + N    DSG
Sbjct: 1746 SLLAKGQTAYIYCNISSYPTANITWKRNG-AVLKGPRYNVFT--NNFTLAIYNAVFEDSG 1802

Query: 335  HYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRET 379
             Y   A+N  G    S  ++V     S +    S+ + +  QR T
Sbjct: 1803 QYECTAQNWLG--TASANVSVSVGMPSSIATAPSKTVVNPSQRVT 1845



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 1185 NPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATS 1244
            +P  +++G+  ++ C +     PT  + W  NG +V  G R+  + +  F  L I +A  
Sbjct: 1744 SPSLLAKGQTAYIYCNISSY--PTANITWKRNG-AVLKGPRYNVFTN-NFT-LAIYNAVF 1798

Query: 1245 ADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVT 1277
             D+G+Y   A N LG+A  +  V V   S I T
Sbjct: 1799 EDSGQYECTAQNWLGTASANVSVSVGMPSSIAT 1831



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 19/163 (11%)

Query: 3073 IPTGDQSMVIEWFYNGKTIEA----SHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNK 3128
            +P     ++ +W  +GK I+     S RI T  +  +VV  +   + +D G Y+C   N 
Sbjct: 1666 VPPVVTPIISDWLKDGKPIDENDVKSLRITTDTSGQLVVNNV---QRSDFGNYTCVLKNS 1722

Query: 3129 WGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHN 3188
             G    S  +     +  + PR      ++  L  GQ+A+  C +     P   I W  N
Sbjct: 1723 AGSISASTIV-----TVNEAPRVVDFSPSL--LAKGQTAYIYCNISSY--PTANITWKRN 1773

Query: 3189 GQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            G  ++        ++F   + +  +    DSG+Y C A N  G
Sbjct: 1774 GAVLKGPRYNVFTNNFTLAIYNAVF---EDSGQYECTAQNWLG 1813



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 7/80 (8%)

Query: 3294 LVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTF-HDFGIVILDILYCYEENS 3352
            L +GQ+A+    +     P   + W  NG  L  G RY  F ++F + I + ++   E+S
Sbjct: 1748 LAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYNVFTNNFTLAIYNAVF---EDS 1801

Query: 3353 GEYECVATNKLGRDSTKANL 3372
            G+YEC A N LG  S   ++
Sbjct: 1802 GQYECTAQNWLGTASANVSV 1821



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 7/140 (5%)

Query: 3508 ASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTPSDL 3567
            +S+   G   + LE    K +EG+I  +   +GY G  +     A     PEF   P++ 
Sbjct: 1594 SSLCYNGVTCVDLELLTNKQIEGSIC-LQCPDGYMGDGELCRVIASIA--PEFQVQPANN 1650

Query: 3568 ILSENSSA-HFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKT--INDFGFVILEIGGVYQ 3624
            I +   SA    CR +P   + +  +W  +GKP +  + VK+  I       L +  V +
Sbjct: 1651 ITTTTESAFRIGCRSVPPVVTPIISDWLKDGKP-IDENDVKSLRITTDTSGQLVVNNVQR 1709

Query: 3625 RDAGLYTCKATNRHGEATVS 3644
             D G YTC   N  G  + S
Sbjct: 1710 SDFGNYTCVLKNSAGSISAS 1729



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 7/97 (7%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEA----SSRITTFFNF 964
            PEF+    + I+           R  P   + +  +WLKDG+P++     S RITT  + 
Sbjct: 1641 PEFQVQPANNITTTTESAFRIGCRSVPPVVTPIISDWLKDGKPIDENDVKSLRITTDTSG 1700

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
                L + +V   D G+YTC   N+ G  + S  +T+
Sbjct: 1701 ---QLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTV 1734



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            L +GQ  Y+   +   + P   I W +NG  L        T +F   TL+I +   +DSG
Sbjct: 1748 LAKGQTAYIYCNIS--SYPTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSG 1802

Query: 2714 IYTCKATNLLGEAVSTASIKI 2734
             Y C A N LG A +  S+ +
Sbjct: 1803 QYECTAQNWLGTASANVSVSV 1823



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 10/111 (9%)

Query: 255  EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVT-----WFKNGQRLINS 309
            E+ R +  ++P +   +P N+ +    ++ F++     P P VT     W K+G+ +  +
Sbjct: 1631 ELCRVIASIAP-EFQVQPANN-ITTTTESAFRIGCRSVP-PVVTPIISDWLKDGKPIDEN 1687

Query: 310  NKHEI-ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV-ESP 358
            +   + ITT     L V N Q+SD G+YT + +N  G I  S  + V E+P
Sbjct: 1688 DVKSLRITTDTSGQLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTVNEAP 1738



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 28/82 (34%), Positives = 37/82 (45%), Gaps = 7/82 (8%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT-THDFGYVALDILYTYAEDS 2179
            L +G  A+  C +     P   I W  NG  ++ G RY   T++F    L I     EDS
Sbjct: 1748 LAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYNVFTNNF---TLAIYNAVFEDS 1801

Query: 2180 GTYMCKATNKLGEAVNTCTLKV 2201
            G Y C A N LG A    ++ V
Sbjct: 1802 GQYECTAQNWLGTASANVSVSV 1823



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 5/85 (5%)

Query: 2256 EGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEY 2315
            +G+TA+  C +     P   I +  NG  L+       T +F   +L I + V ED+G+Y
Sbjct: 1750 KGQTAYIYCNISSY--PTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSGQY 1804

Query: 2316 SVKAINALGHCTSAISMTVTAKGSI 2340
               A N LG  ++ +S++V    SI
Sbjct: 1805 ECTAQNWLGTASANVSVSVGMPSSI 1829



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 3432 LREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSG 3491
            L +G+ A+    ++    P   + W  NG  LK G R+  F +  F +   +  + EDSG
Sbjct: 1748 LAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYNVFTN-NFTLAIYNAVF-EDSG 1802

Query: 3492 EYLCRAYNNYGEAVTTASMKV 3512
            +Y C A N  G A    S+ V
Sbjct: 1803 QYECTAQNWLGTASANVSVSV 1823



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 5/71 (7%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + +GQTA+  C +     PT  + W RN  +++       T++F   ++ I +   ED G
Sbjct: 1748 LAKGQTAYIYCNISSY--PTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSG 1802

Query: 2448 VYMCRASNLLG 2458
             Y C A N LG
Sbjct: 1803 QYECTAQNWLG 1813



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 7/78 (8%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKS-THDFSYVSLDITHTYEEDSGI 2845
            +G   +  CN+  S  PT  I W  N   L  G RY   T++F+   L I +   EDSG 
Sbjct: 1750 KGQTAYIYCNI--SSYPTANITWKRNGAVL-KGPRYNVFTNNFT---LAIYNAVFEDSGQ 1803

Query: 2846 YTCKATNSKGSATTSGSL 2863
            Y C A N  G+A+ + S+
Sbjct: 1804 YECTAQNWLGTASANVSV 1821



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 9/102 (8%)

Query: 1710 APVFTM-PMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN----RLTTMHD 1764
            AP F + P  +I      A     R +P     +  +WL++G PI+ ++    R+TT   
Sbjct: 1640 APEFQVQPANNITTTTESAFRIGCRSVPPVVTPIISDWLKDGKPIDENDVKSLRITT-DT 1698

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKA 1806
             G + +N   V   D G YTC   N  G ++++ST+   ++A
Sbjct: 1699 SGQLVVN--NVQRSDFGNYTCVLKNSAG-SISASTIVTVNEA 1737



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 24/62 (38%), Positives = 30/62 (48%), Gaps = 3/62 (4%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKAT 3918
            P   I W RNG +L  G RY  V+   F +L I     EDSG+Y C A N  G      +
Sbjct: 1764 PTANITWKRNGAVL-KGPRYN-VFTNNF-TLAIYNAVFEDSGQYECTAQNWLGTASANVS 1820

Query: 3919 IS 3920
            +S
Sbjct: 1821 VS 1822



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 30/106 (28%), Positives = 42/106 (39%), Gaps = 6/106 (5%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGF 3614
            G P    T PS  +++ +     +C           V W  +G  + TG     + + G 
Sbjct: 1824 GMPSSIATAPSKTVVNPSQRVTLKCNA--TGQPQPVVTWKKDGVTIKTGPN--RVVEPG- 1878

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQ 3660
              L IG V + D G+Y C A N    ATV   + V G   I   PQ
Sbjct: 1879 -TLTIGVVSRADTGMYACIAQNPQNIATVFSSVIVSGPPIINRPPQ 1923



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 5/70 (7%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKT-TYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTS 2065
            PT  + W  NG  V +G R+   T +F    L I  A  ED+G Y C A N +G A    
Sbjct: 1764 PTANITWKRNGA-VLKGPRYNVFTNNF---TLAIYNAVFEDSGQYECTAQNWLGTASANV 1819

Query: 2066 SVKVDAKSGL 2075
            SV V   S +
Sbjct: 1820 SVSVGMPSSI 1829



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 7/104 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCR-VEPVGDPTMRIDWFHNGRPFATG---SRVHTLNDF 3750
            P F V+  +NI           CR V PV  P +  DW  +G+P       S   T +  
Sbjct: 1641 PEFQVQPANNITTTTESAFRIGCRSVPPVVTPIIS-DWLKDGKPIDENDVKSLRITTDTS 1699

Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            G   L ++ +   D G YTC   N  GS + +  +T +    +V
Sbjct: 1700 G--QLVVNNVQRSDFGNYTCVLKNSAGSISASTIVTVNEAPRVV 1741



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 3/54 (5%)

Query: 1608 TLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEA 1661
            T  + W  N   LK       TNNF    L I + + EDSG Y C A N LG A
Sbjct: 1765 TANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSGQYECTAQNWLGTA 1815



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 7/89 (7%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V   PR V    S+  + +GQ  +  C +     +N  + W +NG  V  G R+    +
Sbjct: 1733 TVNEAPRVVDFSPSL--LAKGQTAYIYCNISSYPTAN--ITWKRNGA-VLKGPRYNVFTN 1787

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527
                 L I + + EDSG Y C A N +GT
Sbjct: 1788 --NFTLAIYNAVFEDSGQYECTAQNWLGT 1814



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 782  LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
            L +G+ A+    ++  S PT  + W ++G  +          NF   +L I +   ED+G
Sbjct: 1748 LAKGQTAYIYCNIS--SYPTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSG 1802

Query: 842  SYTVRAVNKLGEAISTASIRVAARSTV 868
             Y   A N LG A +  S+ V   S++
Sbjct: 1803 QYECTAQNWLGTASANVSVSVGMPSSI 1829



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799
            P   + W RNG  ++        ++F     N  +   EDSG Y C A N LG A  + +
Sbjct: 1764 PTANITWKRNGAVLKGPRYNVFTNNFTLAIYNAVF---EDSGQYECTAQNWLGTASANVS 1820

Query: 1800 LFVQSKASL 1808
            + V   +S+
Sbjct: 1821 VSVGMPSSI 1829



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 7/75 (9%)

Query: 2517 PSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRT-THDFGFVTLDINSVVA 2575
            PS L +GQ A+    +     P+    W  NG  LK G R+   T++F   TL I + V 
Sbjct: 1745 PSLLAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYNVFTNNF---TLAIYNAVF 1798

Query: 2576 NDAGLYMCKAINRAG 2590
             D+G Y C A N  G
Sbjct: 1799 EDSGQYECTAQNWLG 1813



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 7/80 (8%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKL-TSDFGFVTLDLVDVYERDS 2981
            L +GQ  ++   +   + P   I W  NG VL+ G R+ + T++F   TL + +    DS
Sbjct: 1748 LAKGQTAYIYCNIS--SYPTANITWKRNGAVLK-GPRYNVFTNNF---TLAIYNAVFEDS 1801

Query: 2982 GIYTCKAYNKRGEAFTSSTV 3001
            G Y C A N  G A  + +V
Sbjct: 1802 GQYECTAQNWLGTASANVSV 1821



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 6/98 (6%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            +TV +AP+      ++   +G   ++ C +      T  + W  NG  +K G R+   + 
Sbjct: 1732 VTVNEAPRVVDFSPSL-LAKGQTAYIYCNISSY--PTANITWKRNGAVLK-GPRYN-VFT 1786

Query: 1365 FDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             ++      +V+ EDSG Y C A N LG A  + ++ V
Sbjct: 1787 NNFTLAIYNAVF-EDSGQYECTAQNWLGTASANVSVSV 1823



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 5/90 (5%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            + +GQ+A+    +   S  T  + W  NG  +         ++F    L I +   EDSG
Sbjct: 1748 LAKGQTAYIYCNIS--SYPTANITWKRNGAVLKGPRYNVFTNNF---TLAIYNAVFEDSG 1802

Query: 1115 VYTVVARNAAGEAQLSASMTVETRSSIDTS 1144
             Y   A+N  G A  + S++V   SSI T+
Sbjct: 1803 QYECTAQNWLGTASANVSVSVGMPSSIATA 1832


>SB_50799| Best HMM Match : I-set (HMM E-Value=0)
          Length = 1195

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 98/399 (24%), Positives = 151/399 (37%), Gaps = 61/399 (15%)

Query: 4430 FEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489
            F     G P P + W   +F   N P++ I       + +      E +  +   A++R 
Sbjct: 662  FTCSASGIPTPQLTW---SFSGGNLPNYDIDGNKLSIVNVQNNASYEGN--YTCTADSRA 716

Query: 4490 GTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549
            G    +A L V           +P    L  + +    G  V+L  + +G       W  
Sbjct: 717  GRTSFTAMLTVHA---------LPKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTY 767

Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             G  + P  R  +  ED    L++ +  P  +G Y C+A N+ G    + + +V +    
Sbjct: 768  KGVPISP--RENVQLEDDNRLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVG- 824

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIV-AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKP--- 4665
                           I+ PL +K++  EGQ +  +C   G PLP V WY  DK+I     
Sbjct: 825  ---------------IVVPLPEKVIFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDG 869

Query: 4666 SKYF---QMSRTADEYTLRISEAFPEDEGDYKCVAYN-----SAGRVTVAAKLKVTQPDQ 4717
            S+Y     +S    E TLR++     D G+Y CV  N     S+G+VTV     VT   Q
Sbjct: 870  SRYSITNNVSGVRLESTLRLNNTRFGDRGNYSCVFKNHGVNKSSGQVTV----HVTPNVQ 925

Query: 4718 ADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQ--MIHEGNN 4775
                P    L D +        F          ++ W ++G  +   PD +   I    N
Sbjct: 926  NITAPVSPRLGDNITLVCVVRGFPDL-------SVNWTKDGRKLVTRPDRKELSITPQEN 978

Query: 4776 AV----LLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            AV    L I      DTG + C A     + E S  + V
Sbjct: 979  AVKFAYLKIWKAKRSDTGGYQCVAYIKQSKDERSTSVTV 1017



 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 54/194 (27%), Positives = 84/194 (43%), Gaps = 16/194 (8%)

Query: 387 EKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESG 446
           E    P+   + + + V   +   F C  +G P P++TW  +   +    N+ I     G
Sbjct: 638 EVLFKPELELLPKSQTVLVNRTVVFTCSASGIPTPQLTWSFSGGNLP---NYDI----DG 690

Query: 447 NHALMITNV--TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
           N  L I NV    S  G  TC A +++G T+F   L V    ++   K + +  TL    
Sbjct: 691 NK-LSIVNVQNNASYEGNYTCTADSRAGRTSFTAMLTVHALPKIT--KLLNK--TLVAER 745

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
           G  V L+ +A G PTP+  W   GVPI P   +++  D     L + +        Y+C 
Sbjct: 746 GSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDDN--RLLILKKVSPVSNGVYRCI 803

Query: 565 AQNVAGSTATRARL 578
           A N  G+  T  +L
Sbjct: 804 AYNAEGNDTTETKL 817



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 91/354 (25%), Positives = 142/354 (40%), Gaps = 43/354 (12%)

Query: 234 VSFRESITKRYVGESDVQISTEIDR-----SLGPVSPPKIAQKPRNSKLQEGADAQFQVQ 288
           V F    T RY G  + + S+         SL    PPKIA    ++ LQ          
Sbjct: 406 VVFNVQNTDRYEGSYECEASSRAGNASSSASLTVYDPPKIANVLGDTTLQVRGTLNLTCV 465

Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348
             G+P PRV W + G     S++ ++  T+++ TL +  T+  DSG+YT +A N  G   
Sbjct: 466 ALGDPAPRVYWVREGA---GSSRFKL--TNDNKTLVIFQTEYRDSGNYTCIASNRAGNTS 520

Query: 349 TSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDV----T 404
            +  + ++ P   +V ++   Y  +            +   L   +VK  +  ++     
Sbjct: 521 LAKQVDIQVPASVFVDNKTRVYSRNETNATIGCHGNGNPVPLLFWWVKGNKIPEIEALRP 580

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
             K           P   VT ++  R     Y       E+GN+    TN+ L   GV  
Sbjct: 581 ADKSNVVQVTSVAGPMENVTSYLYLRIAGITY------EEAGNYTCNSTNIVL---GVTR 631

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
            V+R  + E  F+  L ++ K Q V    V R           VV    A G PTP++TW
Sbjct: 632 SVSR--TVEVLFKPELELLPKSQTV---LVNR----------TVVFTCSASGIPTPQLTW 676

Query: 525 QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
              G   +PN ++    DG   ++   +  AS    Y CTA + AG T+  A L
Sbjct: 677 SFSG-GNLPNYDI----DGNKLSIVNVQNNASYEGNYTCTADSRAGRTSFTAML 725



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 88/385 (22%), Positives = 147/385 (38%), Gaps = 43/385 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G+P P + W RE      S  F++ T   K+ L+I Q    DS  +  +A NR G    +
Sbjct: 468  GDPAPRVYWVREG---AGSSRFKL-TNDNKT-LVIFQTEYRDSGNYTCIASNRAGNTSLA 522

Query: 4496 ANLVVEEKRRQGRGGIVPPS-FTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
              + ++          VP S F      V   +     +     G     ++W   G K+
Sbjct: 523  KQVDIQ----------VPASVFVDNKTRVYSRNETNATIGCHGNGNPVPLLFWWVKGNKI 572

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSG------KYECVAINSAGEARCDAECVVSLPAT 4608
             P+I      +      +   A P ++       +   +    AG   C++  +V L  T
Sbjct: 573  -PEIEALRPADKSNVVQVTSVAGPMENVTSYLYLRIAGITYEEAGNYTCNSTNIV-LGVT 630

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSK 4667
            +   +  T      PE+    K + V   + + F+C   G P P + W + G  L     
Sbjct: 631  RSVSR--TVEVLFKPELELLPKSQTVLVNRTVVFTCSASGIPTPQLTWSFSGGNL---PN 685

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
            Y           ++ + ++   EG+Y C A + AGR +  A L V        LP +T L
Sbjct: 686  YDIDGNKLSIVNVQNNASY---EGNYTCTADSRAGRTSFTAMLTVHA------LPKITKL 736

Query: 4728 --RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
              + +V   G   Q   Q +    P  +W  +G  +P +P   +  E +N +L++     
Sbjct: 737  LNKTLVAERGSNVQLSCQASGDPTPKYKWTYKG--VPISPRENVQLEDDNRLLILKKVSP 794

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
               G + C A  A G   T  KL+V
Sbjct: 795  VSNGVYRCIAYNAEGNDTTETKLIV 819



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 47/191 (24%), Positives = 87/191 (45%), Gaps = 17/191 (8%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTL 4680
            P   +EP+    V  G+   F+C++ G P P ++W Y G  L     +  ++ T   + +
Sbjct: 354  PECAVEPISGDTVV-GKNFTFTCRVEGIPKPDIKWKYNGGPL--NLAHSTINNTLVVFNV 410

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            + ++ +   EG Y+C A + AG  + +A L V  P +  N+     L D  +        
Sbjct: 411  QNTDRY---EGSYECEASSRAGNASSSASLTVYDPPKIANV-----LGDTTLQVRGTLNL 462

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
                     P + W+REGA    +  F++ ++  N  L+I  T   D+G +TC A+  AG
Sbjct: 463  TCVALGDPAPRVYWVREGA---GSSRFKLTND--NKTLVIFQTEYRDSGNYTCIASNRAG 517

Query: 4801 QVETSAKLVVK 4811
                + ++ ++
Sbjct: 518  NTSLAKQVDIQ 528



 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 19/174 (10%)

Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-- 459
           D   GK   F CRV G P P++ W  N   +        L + + N+ L++ NV  +D  
Sbjct: 364 DTVVGKNFTFTCRVEGIPKPDIKWKYNGGPLN-------LAHSTINNTLVVFNVQNTDRY 416

Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519
            G   C A +++G  +    L V +  ++     V   +TL VR    + L   A+G P 
Sbjct: 417 EGSYECEASSRAGNASSSASLTVYDPPKIAN---VLGDTTLQVR--GTLNLTCVALGDPA 471

Query: 520 PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
           PR+ W ++G     +   ++  D    TL I + +  D+  Y C A N AG+T+
Sbjct: 472 PRVYWVREGA---GSSRFKLTNDN--KTLVIFQTEYRDSGNYTCIASNRAGNTS 520



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 52/174 (29%), Positives = 74/174 (42%), Gaps = 21/174 (12%)

Query: 405  EGKMTRFDCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESG---NHALMITNVTLSD 459
            EG+     C   G P P VTW+  D+ I   D   + I  N SG      L + N    D
Sbjct: 837  EGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRFGD 896

Query: 460  SGVVTCVARNKS-GETAFQCRLNVIEKEQ-VVAPKFVERFSTLNVREGEPVVLNARAVGT 517
             G  +CV +N    +++ Q  ++V    Q + AP        ++ R G+ + L     G 
Sbjct: 897  RGNYSCVFKNHGVNKSSGQVTVHVTPNVQNITAP--------VSPRLGDNITLVCVVRGF 948

Query: 518  PTPRITWQKDGVPIIPNP---ELRIHTDGGA---STLDIPRAKASDAAWYQCTA 565
            P   + W KDG  ++  P   EL I     A   + L I +AK SD   YQC A
Sbjct: 949  PDLSVNWTKDGRKLVTRPDRKELSITPQENAVKFAYLKIWKAKRSDTGGYQCVA 1002



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 96/423 (22%), Positives = 155/423 (36%), Gaps = 73/423 (17%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+  +   + +     F     G P P I W             Q+   S     + 
Sbjct: 67   PEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDALPQGSHQLSNGSLNVAAVY 126

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
              V  E   ++  +A +  G A+ +A+L+V+          VPPS      +  V   Q 
Sbjct: 127  NNVSYE--GLYTCLASSEAGMAQANASLIVD----------VPPSVLSLRGDSTVILEQT 174

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            + L   V       VYW K+G+     I           TL+   +     G+Y C A N
Sbjct: 175  INLTCVVRA-----VYWKKDGQ-----IITTATLSGNNRTLITQASRVALKGRYACFATN 224

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE-FSCKIVGK 4649
             AG    D++ ++                  PP++       I + G       C   GK
Sbjct: 225  RAGN---DSKSILI-------------TVTVPPKVYVAETVAIFSRGDVNRTLHCHGNGK 268

Query: 4650 PLPTVQWYK--GDKL-----IKPSKYFQMSRTADEYT------------LRISEAFPEDE 4690
            P P V W K  G  +     +  +  F++ +  D  T            LR +    ++ 
Sbjct: 269  PPPRVTWSKVGGASIPFVQSLSVNDNFRVVQIQDNRTTSVLQNVTGILYLRTAGITYKEA 328

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR-DIVVYEGQPAQFKTQITSKIK 4749
            G+Y CVA N  G  +V++ ++V    +     A+ P+  D VV  G+   F  ++    K
Sbjct: 329  GNYTCVAENGIGIGSVSSTIEVIFKPEC----AVEPISGDTVV--GKNFTFTCRVEGIPK 382

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED--TGTFTCRATTAAGQVETSAK 4807
            P I+W   G          + H   N  L++ N    D   G++ C A++ AG   +SA 
Sbjct: 383  PDIKWKYNGG------PLNLAHSTINNTLVVFNVQNTDRYEGSYECEASSRAGNASSSAS 436

Query: 4808 LVV 4810
            L V
Sbjct: 437  LTV 439



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 52/181 (28%), Positives = 80/181 (44%), Gaps = 20/181 (11%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+F +  + + + +G    F C  +GRP P +TW  N        +H+ L N S N A +
Sbjct: 67  PEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDALPQGSHQ-LSNGSLNVAAV 125

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
             NV  S  G+ TC+A +++G       L +++    V P      S L++R    V+L 
Sbjct: 126 YNNV--SYEGLYTCLASSEAGMAQANASL-IVD----VPP------SVLSLRGDSTVILE 172

Query: 512 ARAVGTPTPR-ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                T   R + W+KDG  II    L     G   TL    ++ +    Y C A N AG
Sbjct: 173 QTINLTCVVRAVYWKKDG-QIITTATL----SGNNRTLITQASRVALKGRYACFATNRAG 227

Query: 571 S 571
           +
Sbjct: 228 N 228



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 8/134 (5%)

Query: 392 PQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           P+  K+     V E G   +  C+ +G P P+  W      I    N ++   E  N  L
Sbjct: 731 PKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQL---EDDNRLL 787

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           ++  V+   +GV  C+A N  G    + +L V     +V P   E+   +   EG+P+ L
Sbjct: 788 ILKKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIVVP-LPEKVIFM---EGQPLNL 843

Query: 511 NARAVGTPTPRITW 524
              A G P P +TW
Sbjct: 844 TCAAEGIPLPNVTW 857



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 80/323 (24%), Positives = 118/323 (36%), Gaps = 42/323 (13%)

Query: 4411 PIFTKKMQPCRVFEH-EQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P  TK +    V E     +   +  G+P P  KW  +  PI  SP   +       +LI
Sbjct: 731  PKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPI--SPRENVQLEDDNRLLI 788

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            +++V    + V+  +A N  G       L+V         GIV P      + V    GQ
Sbjct: 789  LKKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSV-----GIVVP----LPEKVIFMEGQ 839

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKV-QPD-----IRNKILEEDGTYTLLILEAYPQDSGK 4583
             + L     G    +V W    K + Q D     I N +       TL +      D G 
Sbjct: 840  PLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRFGDRGN 899

Query: 4584 YECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFS 4643
            Y CV  N  G  +   +  V +      P  Q   A   P +           G  I   
Sbjct: 900  YSCVFKNH-GVNKSSGQVTVHVT-----PNVQNITAPVSPRL-----------GDNITLV 942

Query: 4644 CKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYT-----LRISEAFPEDEGDYKCVA 4697
            C + G P  +V W K G KL+      ++S T  E       L+I +A   D G Y+CVA
Sbjct: 943  CVVRGFPDLSVNWTKDGRKLVTRPDRKELSITPQENAVKFAYLKIWKAKRSDTGGYQCVA 1002

Query: 4698 YNSAGRVTVAAKLKVTQ-PDQAD 4719
            Y    +   +  + V + PD+ +
Sbjct: 1003 YIKQSKDERSTSVTVLERPDRPE 1025



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 87/400 (21%), Positives = 151/400 (37%), Gaps = 64/400 (16%)

Query: 4430 FEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRG 4489
            F    +G P P IKW     P+  +      T +   ++   Q        +   A +R 
Sbjct: 373  FTCRVEGIPKPDIKWKYNGGPLNLAHS----TINNTLVVFNVQNTDRYEGSYECEASSRA 428

Query: 4490 GTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549
            G A  SA+L V +          PP       +  +     + L     G     VYW++
Sbjct: 429  GNASSSASLTVYD----------PPKIANVLGDTTLQVRGTLNLTCVALGDPAPRVYWVR 478

Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK 4609
             G       R K+  ++ T  L+I +   +DSG Y C+A N AG      +  + +PA+ 
Sbjct: 479  EGAGSS---RFKLTNDNKT--LVIFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPAS- 532

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQA-IEFSCKIVGKPLPTVQWY-KGDKL----- 4662
                           +    K ++ +  +      C   G P+P + W+ KG+K+     
Sbjct: 533  ---------------VFVDNKTRVYSRNETNATIGCHGNGNPVPLLFWWVKGNKIPEIEA 577

Query: 4663 IKP---SKYFQMSRTA---DEYT----LRISEAFPEDEGDYKCVAYNSAGRVT--VAAKL 4710
            ++P   S   Q++  A   +  T    LRI+    E+ G+Y C + N    VT  V+  +
Sbjct: 578  LRPADKSNVVQVTSVAGPMENVTSYLYLRIAGITYEEAGNYTCNSTNIVLGVTRSVSRTV 637

Query: 4711 KVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMI 4770
            +V    + + LP     +   V   +   F    +    P + W   G      P++ + 
Sbjct: 638  EVLFKPELELLP-----KSQTVLVNRTVVFTCSASGIPTPQLTWSFSGG---NLPNYDI- 688

Query: 4771 HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             +GN   ++         G +TC A + AG+   +A L V
Sbjct: 689  -DGNKLSIVNVQNNASYEGNYTCTADSRAGRTSFTAMLTV 727



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 55/240 (22%), Positives = 94/240 (39%), Gaps = 35/240 (14%)

Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            +++  +  VAEN  G    S+ + V          I  P   +   + +   G+      
Sbjct: 326  KEAGNYTCVAENGIGIGSVSSTIEV----------IFKPECAVEPISGDTVVGKNFTFTC 375

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            +V G    D+ W  NG  +  ++ +  +  + T  +  ++   +  G YEC A + AG A
Sbjct: 376  RVEGIPKPDIKWKYNGGPL--NLAHSTI--NNTLVVFNVQNTDRYEGSYECEASSRAGNA 431

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
               A   V                  PP+I   L D  +     +  +C  +G P P V 
Sbjct: 432  SSSASLTVY----------------DPPKIANVLGDTTLQVRGTLNLTCVALGDPAPRVY 475

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
            W +       S  F++  T D  TL I +    D G+Y C+A N AG  ++A ++ +  P
Sbjct: 476  WVREGA---GSSRFKL--TNDNKTLVIFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVP 530



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 44/170 (25%), Positives = 71/170 (41%), Gaps = 17/170 (10%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I+W YNG  +  +H   +     +VV  +  T   + G+Y C A+++ G A  S  L   
Sbjct: 385  IKWKYNGGPLNLAH---STINNTLVVFNVQNTDRYE-GSYECEASSRAGNASSSASLTVY 440

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            D  K       T +Q + G           T V + DP  ++ W   G     S+R K  
Sbjct: 441  DPPKIANVLGDTTLQ-VRGT-------LNLTCVALGDPAPRVYWVREGAG---SSRFKLT 489

Query: 3202 SDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGKGGVYLES 3251
            +D   +V  I  T+  DSG Y C A N+ G       ++      V++++
Sbjct: 490  NDNKTLV--IFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPASVFVDN 537



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+  + PR+  +++G    F    SG P+PR+TW  NG   +    H++     +     
Sbjct: 67  PEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDALPQGSHQLSNGSLNVAAVY 126

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            N   S  G YT LA +  G    +  L V+ P
Sbjct: 127 NNV--SYEGLYTCLASSEAGMAQANASLIVDVP 157



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 18/142 (12%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEG-LK 3162
            G++ L   G    ++G Y+C A N  G   +S  +E + K +         ++ I G   
Sbjct: 314  GILYLRTAGITYKEAGNYTCVAENGIGIGSVSSTIEVIFKPE-------CAVEPISGDTV 366

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMR--HSTRIKTVSDFGFVVLDIAYTQNHDSG 3220
             G++  F C V  +  PD+K  W +NG P+   HST   T+     VV ++  T  ++ G
Sbjct: 367  VGKNFTFTCRVEGIPKPDIK--WKYNGGPLNLAHSTINNTL-----VVFNVQNTDRYE-G 418

Query: 3221 EYVCRAYNKYGEDFTRATINCY 3242
             Y C A ++ G   + A++  Y
Sbjct: 419  SYECEASSRAGNASSSASLTVY 440



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 64/271 (23%), Positives = 104/271 (38%), Gaps = 43/271 (15%)

Query: 4547 WLKNGKKVQPD-IRNKILEEDGTYTLLILEAYPQ--DSGKYECVAINSAGEARCDAECVV 4603
            W K+G  V PD  +N  + E    ++    +     D+G Y C A+N+A +    +  + 
Sbjct: 3    WSKDGSAVAPDRYQNTEVSETNISSVFEFSSGTTYADAGNYTCHAVNNADDKGTVSAVIQ 62

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKL 4662
             L                 PE     + + + +G  + F C   G+P P + W Y G   
Sbjct: 63   VL---------------FEPEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDA 107

Query: 4663 IKPSKYFQMSRTADEYTLRISEAF--PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            + P    Q+S      +L ++  +     EG Y C+A + AG     A L V  P     
Sbjct: 108  L-PQGSHQLSNG----SLNVAAVYNNVSYEGLYTCLASSEAGMAQANASLIVDVP----- 157

Query: 4721 LPALTPLR-DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLL 4779
             P++  LR D  V   Q       +T  ++  + W ++G +I           GNN  L+
Sbjct: 158  -PSVLSLRGDSTVILEQ----TINLTCVVR-AVYWKKDGQIITTA-----TLSGNNRTLI 206

Query: 4780 IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
               +     G + C AT  AG    S  + V
Sbjct: 207  TQASRVALKGRYACFATNRAGNDSKSILITV 237



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 51/186 (27%), Positives = 76/186 (40%), Gaps = 31/186 (16%)

Query: 413 CRVTGRPYPEVTWF--------------INDR----QIRDDYNHKILVNESGNHALMITN 454
           C   G+P P VTW               +ND     QI+D+    +L N +G   L    
Sbjct: 263 CHGNGKPPPRVTWSKVGGASIPFVQSLSVNDNFRVVQIQDNRTTSVLQNVTGILYLRTAG 322

Query: 455 VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARA 514
           +T  ++G  TCVA N  G  +    + VI K +      VE  S   V  G+      R 
Sbjct: 323 ITYKEAGNYTCVAENGIGIGSVSSTIEVIFKPECA----VEPISGDTV-VGKNFTFTCRV 377

Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD--AAWYQCTAQNVAGST 572
            G P P I W+ +G P      L +      +TL +   + +D     Y+C A + AG+ 
Sbjct: 378 EGIPKPDIKWKYNGGP------LNLAHSTINNTLVVFNVQNTDRYEGSYECEASSRAGNA 431

Query: 573 ATRARL 578
           ++ A L
Sbjct: 432 SSSASL 437



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 35/99 (35%), Positives = 44/99 (44%), Gaps = 5/99 (5%)

Query: 1305 ITVMQAPQFSRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY 1363
            +TV   P+ ++ L+     E G+NV L C  Q  GD T + +W   G PI    R     
Sbjct: 725  LTVHALPKITKLLNKTLVAERGSNVQLSC--QASGDPTPKYKWTYKGVPISP--RENVQL 780

Query: 1364 EFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            E D   L L  V P  +GVY C A N  G   T   L V
Sbjct: 781  EDDNRLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIV 819



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 8/107 (7%)

Query: 49  TTQVESSGDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRK 108
           T   +S   R   TA       P I + + K     +G N +   +  G+PTP   WT K
Sbjct: 709 TCTADSRAGRTSFTAMLTVHALPKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYK 768

Query: 109 KAPLVECNKYSMRYNEQTGDVS--LLIKQIGPGDEGEYTCTARNQYG 153
             P+      S R N Q  D +  L++K++ P   G Y C A N  G
Sbjct: 769 GVPI------SPRENVQLEDDNRLLILKKVSPVSNGVYRCIAYNAEG 809



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 10/91 (10%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN-KPLPSGTRYKSTHDFSYVSLD 2834
            F  H  +   K+G+++ F C    S  P  +I W +N    LP G+     H  S  SL+
Sbjct: 69   FTRHPRSQTIKQGNHVTFGCAA--SGRPQPRITWLYNGGDALPQGS-----HQLSNGSLN 121

Query: 2835 ITHTYEEDS--GIYTCKATNSKGSATTSGSL 2863
            +   Y   S  G+YTC A++  G A  + SL
Sbjct: 122  VAAVYNNVSYEGLYTCLASSEAGMAQANASL 152



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 16/50 (32%), Positives = 27/50 (54%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            P F   P + T+++G    F C  +G P+PR+ WL NG   +    ++L+
Sbjct: 67   PEFTRHPRSQTIKQGNHVTFGCAASGRPQPRITWLYNGGDALPQGSHQLS 116



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 54/280 (19%), Positives = 94/280 (33%), Gaps = 24/280 (8%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    +  +      G         G+P P V W R+ A        S R+     + +
Sbjct: 442 PPKIANVLGDTTLQVRGTLNLTCVALGDPAPRVYWVREGAG-------SSRFKLTNDNKT 494

Query: 131 LLIKQIGPGDEGEYTCTARNQYG----------EAICSVYIQPEGXXXXXXXXXXXXXYR 180
           L+I Q    D G YTC A N+ G          +   SV++  +                
Sbjct: 495 LVIFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPASVFVDNKTRVYSRNETNATIGCH 554

Query: 181 HVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESI 240
                V    +  +G    +    +    +N    +S      +   Y  LR        
Sbjct: 555 GNGNPVPLLFWWVKGNKIPEIEALRPADKSNVVQVTSVAGPMENVTSYLYLRIAGITYEE 614

Query: 241 TKRYVGESD---VQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRV 297
              Y   S    + ++  + R++  +  P++   P++  +       F    SG P P++
Sbjct: 615 AGNYTCNSTNIVLGVTRSVSRTVEVLFKPELELLPKSQTVLVNRTVVFTCSASGIPTPQL 674

Query: 298 TWFKNGQRL----INSNKHEIITTHNHTTLRVRNTQKSDS 333
           TW  +G  L    I+ NK  I+   N+ +     T  +DS
Sbjct: 675 TWSFSGGNLPNYDIDGNKLSIVNVQNNASYEGNYTCTADS 714



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 7/116 (6%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +PP+      D  L    + +  C  + + D + RV W   G      SR K  ND   +
Sbjct: 441  DPPKIANVLGDTTLQVRGTLNLTC--VALGDPAPRVYWVREGAG---SSRFKLTNDNKTL 495

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTES 3671
            +  I     RD+G YTC A+NR G  +++ ++ ++    + ++ +   + ++ T +
Sbjct: 496  V--IFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPASVFVDNKTRVYSRNETNA 549



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 5/90 (5%)

Query: 445 SGNHALMITNVT-LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR 503
           SGN+  +IT  + ++  G   C A N++G  +    + V    +V   + V  FS  +V 
Sbjct: 199 SGNNRTLITQASRVALKGRYACFATNRAGNDSKSILITVTVPPKVYVAETVAIFSRGDVN 258

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIP 533
                 L+    G P PR+TW K G   IP
Sbjct: 259 R----TLHCHGNGKPPPRVTWSKVGGASIP 284



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 60/291 (20%), Positives = 105/291 (36%), Gaps = 22/291 (7%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P  E + K+          F     G PTP ++W+     L         Y+     +S+
Sbjct: 643 PELELLPKSQTVLVNRTVVFTCSASGIPTPQLTWSFSGGNLPN-------YDIDGNKLSI 695

Query: 132 LIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAY 191
           +  Q     EG YTCTA ++ G    +  +                     S      + 
Sbjct: 696 VNVQNNASYEGNYTCTADSRAGRTSFTAMLTVHALPKITKLLNKTLVAERGSNV--QLSC 753

Query: 192 GTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKV-DTFEYRLLREVSFRESITKRYVGESDV 250
              G  T + + T K     G   S  ++ ++ D     +L++VS   +   R +  +  
Sbjct: 754 QASGDPTPKYKWTYK-----GVPISPRENVQLEDDNRLLILKKVSPVSNGVYRCIAYNAE 808

Query: 251 QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
              T   + +  VS   +   P      EG          G P P VTW+   + +  ++
Sbjct: 809 GNDTTETKLIVHVSVGIVVPLPEKVIFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTD 868

Query: 311 KHEIITTHN------HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
                 T+N       +TLR+ NT+  D G+Y+ + +N +G   +SG + V
Sbjct: 869 GSRYSITNNVSGVRLESTLRLNNTRFGDRGNYSCVFKN-HGVNKSSGQVTV 918



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P  T  +    VAE + ++ +      GDP  + +W   GVPI     +    D   + L
Sbjct: 731  PKITKLLNKTLVAE-RGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDDNRLLIL 789

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFV 1802
              K V+P  +G Y C A N  G   T + L V
Sbjct: 790  --KKVSPVSNGVYRCIAYNAEGNDTTETKLIV 819



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 10/86 (11%)

Query: 1859 GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGED--SGE 1916
            G++  + CR+E  P P+  ++W +NG  L   H   T N+     L +  V   D   G 
Sbjct: 368  GKNFTFTCRVEGIPKPD--IKWKYNGGPLNLAHS--TINN----TLVVFNVQNTDRYEGS 419

Query: 1917 YTCKAINNLGQAVSSIRLNVQSKESI 1942
            Y C+A +  G A SS  L V     I
Sbjct: 420  YECEASSRAGNASSSASLTVYDPPKI 445



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            +V + G N+   C  + S DPT K +W +   P+      +   D     L +       
Sbjct: 741  LVAERGSNVQLSC--QASGDPTPKYKWTYKGVPISPRENVQLEDDNRL--LILKKVSPVS 796

Query: 2843 SGIYTCKATNSKGSATTSGSL 2863
            +G+Y C A N++G+ TT   L
Sbjct: 797  NGVYRCIAYNAEGNDTTETKL 817



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 5/73 (6%)

Query: 938  DSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997
            +   RV  ++D R       +T     G + L    +T  +AG+YTC A N IG  + S+
Sbjct: 292  NDNFRVVQIQDNRTTSVLQNVT-----GILYLRTAGITYKEAGNYTCVAENGIGIGSVSS 346

Query: 998  NLTIVTKKDIIAE 1010
             + ++ K +   E
Sbjct: 347  TIEVIFKPECAVE 359



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 6/76 (7%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G N  F C VE    P +K  W +N  PL       ST + + V  ++ +T +   G Y 
Sbjct: 368  GKNFTFTCRVEGIPKPDIK--WKYNGGPLNLA---HSTINNTLVVFNVQNT-DRYEGSYE 421

Query: 2848 CKATNSKGSATTSGSL 2863
            C+A++  G+A++S SL
Sbjct: 422  CEASSRAGNASSSASL 437



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 7/80 (8%)

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG-YVALNMKYVNPEDSGTYTCRAINELGE 1793
            + +GDP  RV W+R G     S+R    +D    V    +Y    DSG YTC A N  G 
Sbjct: 465  VALGDPAPRVYWVREGA---GSSRFKLTNDNKTLVIFQTEY---RDSGNYTCIASNRAGN 518

Query: 1794 AVTSSTLFVQSKASLQLESQ 1813
               +  + +Q  AS+ ++++
Sbjct: 519  TSLAKQVDIQVPASVFVDNK 538



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/101 (25%), Positives = 39/101 (38%), Gaps = 4/101 (3%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+ T  +   +    G  V   C+    GDPT +  W + G P +    V   +D   + 
Sbjct: 731  PKITKLLNKTLVAERGSNVQLSCQAS--GDPTPKYKWTYKGVPISPRENVQLEDDNRLLI 788

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVL 3795
            L    +     G Y C A N  G+ TT  K+       IV+
Sbjct: 789  L--KKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIVV 827



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP+    + D   +   G ++  C    +GDP  R+ W   G   A  SR    ND   
Sbjct: 441  DPPKIANVLGDTT-LQVRGTLNLTCVA--LGDPAPRVYWVREG---AGSSRFKLTNDNKT 494

Query: 3753 IAL-DIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQ 3798
            + +   +Y   RD+G YTC A+N+ G+ +   ++       + ++++
Sbjct: 495  LVIFQTEY---RDSGNYTCIASNRAGNTSLAKQVDIQVPASVFVDNK 538



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 9/127 (7%)

Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNP 293
           ++++E+     V E+ + I + +  ++  +  P+ A +P +     G +  F  ++ G P
Sbjct: 323 ITYKEAGNYTCVAENGIGIGS-VSSTIEVIFKPECAVEPISGDTVVGKNFTFTCRVEGIP 381

Query: 294 RPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD--SGHYTLLAENPNGCIVTSG 351
           +P + W  NG  L  +  H  I    + TL V N Q +D   G Y   A +  G   +S 
Sbjct: 382 KPDIKWKYNGGPL--NLAHSTI----NNTLVVFNVQNTDRYEGSYECEASSRAGNASSSA 435

Query: 352 YLAVESP 358
            L V  P
Sbjct: 436 SLTVYDP 442



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 29/124 (23%), Positives = 49/124 (39%), Gaps = 8/124 (6%)

Query: 3262 ELESLQGAQQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYN 3321
            E  S  G    + S    +PPK    + D T  V G         V + DP  +V W   
Sbjct: 423  EASSRAGNASSSASLTVYDPPKIANVLGDTTLQVRGT---LNLTCVALGDPAPRVYWVRE 479

Query: 3322 GKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLI 3381
            G       R++  +D   ++  I      +SG Y C+A+N+ G  S    +      ++ 
Sbjct: 480  GAG---SSRFKLTNDNKTLV--IFQTEYRDSGNYTCIASNRAGNTSLAKQVDIQVPASVF 534

Query: 3382 LDSQ 3385
            +D++
Sbjct: 535  VDNK 538



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 5/82 (6%)

Query: 1997 LEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
            L  T   + DP  RV W   G       RFK T D     L I      D+G Y C A+N
Sbjct: 460  LNLTCVALGDPAPRVYWVREGAG---SSRFKLTND--NKTLVIFQTEYRDSGNYTCIASN 514

Query: 2057 AVGEAVTTSSVKVDAKSGLYLD 2078
              G       V +   + +++D
Sbjct: 515  RAGNTSLAKQVDIQVPASVFVD 536



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 28/129 (21%), Positives = 50/129 (38%), Gaps = 9/129 (6%)

Query: 3119 GTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD 3178
            G Y+C A ++ G+   +  L     +    P+ T  +      + G +    C      D
Sbjct: 706  GNYTCTADSRAGRTSFTAML-----TVHALPKITKLLNKTLVAERGSNVQLSCQAS--GD 758

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRAT 3238
            P  K +W + G P+     ++   D   ++L      ++  G Y C AYN  G D T   
Sbjct: 759  PTPKYKWTYKGVPISPRENVQLEDDNRLLILKKVSPVSN--GVYRCIAYNAEGNDTTETK 816

Query: 3239 INCYGKGGV 3247
            +  +   G+
Sbjct: 817  LIVHVSVGI 825



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 6/100 (6%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW-YRNGKLLPSGHRYRTVYDMGFVS 3888
            P+F    +S T+++   V F C    +  P  RI W Y  G  LP G         G ++
Sbjct: 67   PEFTRHPRSQTIKQGNHVTFGCAASGRPQP--RITWLYNGGDALPQGSHQ---LSNGSLN 121

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDII 3928
            +  +Y      G Y C A ++ G     A++     P ++
Sbjct: 122  VAAVYNNVSYEGLYTCLASSEAGMAQANASLIVDVPPSVL 161



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F    +S T  +G  + F       G P  +I WL NG   +A  + +     G +++
Sbjct: 67  PEFTRHPRSQTIKQGNHVTFGCAAS--GRPQPRITWLYNGG--DALPQGSHQLSNGSLNV 122

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +  N+   G YTC A S  G+A+  A L V
Sbjct: 123 AAVYNNVSYEGLYTCLASSEAGMAQANASLIV 154



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 3706 DVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDA 3765
            D   G    F CRVE  G P   I W +NG P    +  H+  +   +  ++     R  
Sbjct: 364  DTVVGKNFTFTCRVE--GIPKPDIKWKYNGGPL---NLAHSTINNTLVVFNVQNT-DRYE 417

Query: 3766 GEYTCRATNKWGSATTTAKIT 3786
            G Y C A+++ G+A+++A +T
Sbjct: 418  GSYECEASSRAGNASSSASLT 438



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 6/78 (7%)

Query: 3295 VEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGE 3354
            V G++  F  R+  +  PD+K  W YNG  L   H   T ++  +V+ ++    +   G 
Sbjct: 366  VVGKNFTFTCRVEGIPKPDIK--WKYNGGPLNLAHS--TINNT-LVVFNVQNT-DRYEGS 419

Query: 3355 YECVATNKLGRDSTKANL 3372
            YEC A+++ G  S+ A+L
Sbjct: 420  YECEASSRAGNASSSASL 437



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/62 (38%), Positives = 30/62 (48%), Gaps = 5/62 (8%)

Query: 2940 DPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
            DP  ++ W   G      SRFKLT+D    TL +     RDSG YTC A N+ G    + 
Sbjct: 469  DPAPRVYWVREGA---GSSRFKLTNDNK--TLVIFQTEYRDSGNYTCIASNRAGNTSLAK 523

Query: 3000 TV 3001
             V
Sbjct: 524  QV 525



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 31/126 (24%), Positives = 47/126 (37%), Gaps = 2/126 (1%)

Query: 1545 STQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPV 1604
            + QN A  E        S+  RT     +T  A    T L N  +   + ++ +      
Sbjct: 697  NVQNNASYEGNYTCTADSRAGRTSFTAMLTVHALPKITKLLNKTLVAERGSNVQLSCQAS 756

Query: 1605 SDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
             D T K +W +   P+         ++   + L  +S  P  +G Y C A NA G   T 
Sbjct: 757  GDPTPKYKWTYKGVPISPRENVQLEDDNRLLILKKVS--PVSNGVYRCIAYNAEGNDTTE 814

Query: 1665 GIAIVH 1670
               IVH
Sbjct: 815  TKLIVH 820



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 913  TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIK 972
            T + ++  + E G ++ +   +  GD T + +W   G P+  S R           L +K
Sbjct: 734  TKLLNKTLVAERG-SNVQLSCQASGDPTPKYKWTYKGVPI--SPRENVQLEDDNRLLILK 790

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
             V+    G Y C AYNA G  TT   L +     I+
Sbjct: 791  KVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIV 826



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 5/58 (8%)

Query: 2533 VPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            V +GDP+ R  W   G      SRF+ T+D    TL I      D+G Y C A NRAG
Sbjct: 465  VALGDPAPRVYWVREGAG---SSRFKLTNDNK--TLVIFQTEYRDSGNYTCIASNRAG 517



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 5/98 (5%)

Query: 3976 VTQIQSQTSLVEM-ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMN 4034
            +T++ ++T + E     +  CQ +  GDP  K +W + G P+  +       D   + + 
Sbjct: 733  ITKLLNKTLVAERGSNVQLSCQAS--GDPTPKYKWTYKGVPISPRENVQLEDDNRLLILK 790

Query: 4035 FGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKPGIV 4072
               V P  +G Y C A N  G D T+  +      GIV
Sbjct: 791  --KVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIV 826



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 6/78 (7%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G    F CRVE I  P   I W +NG  +   H   +T +   V  ++  T   + G+Y 
Sbjct: 368  GKNFTFTCRVEGIPKPD--IKWKYNGGPLNLAH---STINNTLVVFNVQNTDRYE-GSYE 421

Query: 2184 CKATNKLGEAVNTCTLKV 2201
            C+A+++ G A ++ +L V
Sbjct: 422  CEASSRAGNASSSASLTV 439



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%)

Query: 1873 DPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSI 1932
            DP  RV W   G       R++ +ND     L I      DSG YTC A N  G    + 
Sbjct: 469  DPAPRVYWVREGA---GSSRFKLTNDN--KTLVIFQTEYRDSGNYTCIASNRAGNTSLAK 523

Query: 1933 RLNVQSKESIIRDSQ 1947
            ++++Q   S+  D++
Sbjct: 524  QVDIQVPASVFVDNK 538



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 8/94 (8%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYV 2300
            P   V  + G T V  GK   F C+VE +  P+  I++ +NG  L  A   H T +   V
Sbjct: 354  PECAVEPISGDTVV--GKNFTFTCRVEGIPKPD--IKWKYNGGPLNLA---HSTINNTLV 406

Query: 2301 SLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              ++Q+      G Y  +A +  G+ +S+ S+TV
Sbjct: 407  VFNVQN-TDRYEGSYECEASSRAGNASSSASLTV 439



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 14/96 (14%)

Query: 3558 PEFTTTP--SDLILSENSSAHFECRL--IPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG 3613
            PE    P   D ++ +N +  F CR+  IP  D    ++W +NG PL       TIN+  
Sbjct: 354  PECAVEPISGDTVVGKNFT--FTCRVEGIPKPD----IKWKYNGGPLNLAH--STINNT- 404

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             V+  +     R  G Y C+A++R G A+ S  L V
Sbjct: 405  LVVFNVQNT-DRYEGSYECEASSRAGNASSSASLTV 439



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 7/86 (8%)

Query: 633 VYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFG 692
           VY PP+    L   T    G ++       +GDP  ++ W++ G     SSRF       
Sbjct: 439 VYDPPKIANVLGDTTLQVRGTLNLTC--VALGDPAPRVYWVREGAG---SSRFK--LTND 491

Query: 693 YISLDMLSLNIQDSGEYTCRAVSATG 718
             +L +     +DSG YTC A +  G
Sbjct: 492 NKTLVIFQTEYRDSGNYTCIASNRAG 517



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 3567 LILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRD 3626
            L+    S+    C+     D + + +W + G P+     V+  +D   +IL+   V    
Sbjct: 741  LVAERGSNVQLSCQAS--GDPTPKYKWTYKGVPISPRENVQLEDDNRLLILK--KVSPVS 796

Query: 3627 AGLYTCKATNRHGEATVSCKLQVKGRQGIIL 3657
             G+Y C A N  G  T   KL V    GI++
Sbjct: 797  NGVYRCIAYNAEGNDTTETKLIVHVSVGIVV 827



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 7/95 (7%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGV-TLTTGARLKSTFDFGLV 2700
            P FT H +S   + +G HV        R  P  +I W  NG   L  G+   S     + 
Sbjct: 67   PEFTRHPRS-QTIKQGNHVTFGCAASGRPQP--RITWLYNGGDALPQGSHQLSNGSLNVA 123

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
             +  N++  +  G+YTC A++  G A + AS+ ++
Sbjct: 124  AV-YNNVSYE--GLYTCLASSEAGMAQANASLIVD 155



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 8/94 (8%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            PEFT  P    + + +   F C          R+ W +NG   L     +  N      L
Sbjct: 67   PEFTRHPRSQTIKQGNHVTFGCAAS--GRPQPRITWLYNGGDALPQGSHQLSNGS----L 120

Query: 3618 EIGGVYQRDA--GLYTCKATNRHGEATVSCKLQV 3649
             +  VY   +  GLYTC A++  G A  +  L V
Sbjct: 121  NVAAVYNNVSYEGLYTCLASSEAGMAQANASLIV 154



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 5/91 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P FT   +    + +G  V F C     G P  RI W +NG   A     H L++ G + 
Sbjct: 67   PEFTRHPRSQT-IKQGNHVTFGCAAS--GRPQPRITWLYNGGD-ALPQGSHQLSN-GSLN 121

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +   Y      G YTC A+++ G A   A +
Sbjct: 122  VAAVYNNVSYEGLYTCLASSEAGMAQANASL 152



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 9/79 (11%)

Query: 3112 GTKTTDSGTYSCRATNKW-GQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            GT   D+G Y+C A N    +  +S  ++ +      +P FT H ++ + +K G    F 
Sbjct: 34   GTTYADAGNYTCHAVNNADDKGTVSAVIQVL-----FEPEFTRHPRS-QTIKQGNHVTFG 87

Query: 3171 CTVVPVDDPDMKIEWYHNG 3189
            C       P  +I W +NG
Sbjct: 88   CAA--SGRPQPRITWLYNG 104



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 4112 VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI--VNGSRYKLT 4160
            + V LP+ V   EG+     C   G P P V W      I   +GSRY +T
Sbjct: 825  IVVPLPEKVIFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSIT 875



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 6/73 (8%)

Query: 1738 GDPKLRVEWLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G P+ R+ WL NG     + S++L+     G + +   Y N    G YTC A +E G A 
Sbjct: 92   GRPQPRITWLYNGGDALPQGSHQLSN----GSLNVAAVYNNVSYEGLYTCLASSEAGMAQ 147

Query: 1796 TSSTLFVQSKASL 1808
             +++L V    S+
Sbjct: 148  ANASLIVDVPPSV 160



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 17/50 (34%), Positives = 26/50 (52%)

Query: 3610 NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            N  G + L   G+  ++AG YTC A N  G  +VS  ++V  +    +EP
Sbjct: 311  NVTGILYLRTAGITYKEAGNYTCVAENGIGIGSVSSTIEVIFKPECAVEP 360



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 4/91 (4%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            PK IT++ + T LV  + ++ +       DP  K +W Y G  +      +   D  ++I
Sbjct: 731  PK-ITKLLNKT-LVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDDNRLLI 788

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            L  +     ++G Y C+A N  G D+T+  L
Sbjct: 789  LKKVS--PVSNGVYRCIAYNAEGNDTTETKL 817



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 8/100 (8%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V+  P+F+R   +    +G +V   C     G    R+ W  NG         + +++
Sbjct: 61   IQVLFEPEFTRHPRSQTIKQGNHVTFGCAAS--GRPQPRITWLYNGGDALP----QGSHQ 114

Query: 1365 FDYVALDLLSVYPEDS--GVYTCQATNQLGEAVTSCALRV 1402
                +L++ +VY   S  G+YTC A+++ G A  + +L V
Sbjct: 115  LSNGSLNVAAVYNNVSYEGLYTCLASSEAGMAQANASLIV 154



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 6/102 (5%)

Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
            V   I V+  P+ +    + +TV G N    CR++  G     ++W  NG P+   H   
Sbjct: 344  VSSTIEVIFKPECAVEPISGDTVVGKNFTFTCRVE--GIPKPDIKWKYNGGPLNLAHS-- 399

Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
                   V  ++ +      G Y C+A+++ G A +S +L V
Sbjct: 400  -TINNTLVVFNVQNT-DRYEGSYECEASSRAGNASSSASLTV 439



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 11/86 (12%)

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVL--QSGHRYRTSNDFGFAALDIL-----TVY 1910
            EGQ  +  C  E  P PN  V WY   K++    G RY  +N+     L+       T +
Sbjct: 837  EGQPLNLTCAAEGIPLPN--VTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRF 894

Query: 1911 GEDSGEYTCKAINNLGQAVSSIRLNV 1936
            G D G Y+C    N G   SS ++ V
Sbjct: 895  G-DRGNYSC-VFKNHGVNKSSGQVTV 918


>SB_40971| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 828

 Score = 75.8 bits (178), Expect = 8e-13
 Identities = 56/169 (33%), Positives = 80/169 (47%), Gaps = 15/169 (8%)

Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470
           F C  +G P P + W   D     + ++K+L    GN  L++ N TL D+G+  C A N 
Sbjct: 228 FHCAASGVPKPVLIWSKVDGAPLMESSYKML----GNGRLVLENTTLEDAGLYECKAINL 283

Query: 471 SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL-NARAVGTPTPRITWQKDGV 529
            GE++   RL V      V P          V+EG+ V+L      G P P I W +   
Sbjct: 284 LGESSATMRLVV-----TVPPSVSIDIGPTYVQEGDNVMLPKCHVTGFPLPEINWTRSAG 338

Query: 530 PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +   P  R+ T GG   L I  A+A+D+  Y C+A+N  GST  R +L
Sbjct: 339 QL---PRRRVMTSGG--QLSILAARANDSGDYFCSARNHIGSTIARTQL 382



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 50/155 (32%), Positives = 68/155 (43%), Gaps = 18/155 (11%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C VTG P PE+ W  +  Q+      +  V  SG   L I     +DSG   C ARN  G
Sbjct: 321 CHVTGFPLPEINWTRSAGQLP-----RRRVMTSGGQ-LSILAARANDSGDYFCSARNHIG 374

Query: 473 ETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREGEPVVLNARAVGTPTPR-ITWQKDGVP 530
            T  + +L V        P+F +    +L    G  V+L  +A G+P P  ITW + G  
Sbjct: 375 STIARTQLVVF-----ALPRFIISPPKSLKAEVGSDVILPCKAYGSPPPLVITWHRHG-K 428

Query: 531 IIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
            IP     +  DG    +D+  A   D+  Y CTA
Sbjct: 429 SIPQERSGV-IDGVLRLIDVTTA---DSGVYVCTA 459



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 69/278 (24%), Positives = 104/278 (37%), Gaps = 42/278 (15%)

Query: 4426 EQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAV 4484
            + A F     G P P++ W + +  P+  S     +       L++    +ED+ ++   
Sbjct: 224  DTAVFHCAASGVPKPVLIWSKVDGAPLMESS----YKMLGNGRLVLENTTLEDAGLYECK 279

Query: 4485 AENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT-KVTGTKPI 4543
            A N  G +  +  LVV           VPPS ++      V  G  V L    VTG    
Sbjct: 280  AINLLGESSATMRLVVT----------VPPSVSIDIGPTYVQEGDNVMLPKCHVTGFPLP 329

Query: 4544 DVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            ++ W ++  ++    R +++   G   L IL A   DSG Y C A N  G      + VV
Sbjct: 330  EINWTRSAGQLP---RRRVMTSGGQ--LSILAARANDSGDYFCSARNHIGSTIARTQLVV 384

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKL 4662
                              P  II P K      G  +   CK  G P P  + W++  K 
Sbjct: 385  FA---------------LPRFIISPPKSLKAEVGSDVILPCKAYGSPPPLVITWHRHGKS 429

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            I   +    S   D   LR+ +    D G Y C A +S
Sbjct: 430  IPQER----SGVIDG-VLRLIDVTTADSGVYVCTATSS 462



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 49/192 (25%), Positives = 69/192 (35%), Gaps = 15/192 (7%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            +AP  I+ P    I A   A+ F C   G P P + W K D        ++M        
Sbjct: 207  SAPNAIVSPALITINASDTAV-FHCAASGVPKPVLIWSKVDGAPLMESSYKMLGNG---R 262

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739
            L +     ED G Y+C A N  G  +   +L VT P           +    V EG    
Sbjct: 263  LVLENTTLEDAGLYECKAINLLGESSATMRLVVTVPPSVS-----IDIGPTYVQEGDNVM 317

Query: 4740 F-KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
              K  +T    P I W R    +P     +++  G    +L       D+G + C A   
Sbjct: 318  LPKCHVTGFPLPEINWTRSAGQLPRR---RVMTSGGQLSILAARA--NDSGDYFCSARNH 372

Query: 4799 AGQVETSAKLVV 4810
             G      +LVV
Sbjct: 373  IGSTIARTQLVV 384



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 10/115 (8%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRF-ECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            +V+ PP     I    V+E + V   +C V     P+  I W R+   LP   R R +  
Sbjct: 294  VVTVPPSVSIDIGPTYVQEGDNVMLPKCHVTGFPLPE--INWTRSAGQLP---RRRVMTS 348

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938
             G   L IL   A DSG+Y C A N  G    +  +    LP  I+    P+ +K
Sbjct: 349  GG--QLSILAARANDSGDYFCSARNHIGSTIARTQLVVFALPRFII--SPPKSLK 399



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTL 548
           AP  +   + + +   +  V +  A G P P + W K DG P++ +    +    G   L
Sbjct: 208 APNAIVSPALITINASDTAVFHCAASGVPKPVLIWSKVDGAPLMESSYKML----GNGRL 263

Query: 549 DIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +      DA  Y+C A N+ G ++   RL
Sbjct: 264 VLENTTLEDAGLYECKAINLLGESSATMRL 293



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 8/86 (9%)

Query: 1852 GPTKLSEGQSAHY-ECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVY 1910
            GPT + EG +    +C +  +P P   + W  +   L    R  TS       L IL   
Sbjct: 306  GPTYVQEGDNVMLPKCHVTGFPLPE--INWTRSAGQLPR-RRVMTSG----GQLSILAAR 358

Query: 1911 GEDSGEYTCKAINNLGQAVSSIRLNV 1936
              DSG+Y C A N++G  ++  +L V
Sbjct: 359  ANDSGDYFCSARNHIGSTIARTQLVV 384



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 945  WLK-DGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003
            W K DG P+  SS    +   G   L +++ T+ DAG Y C+A N +G+++ +  L +  
Sbjct: 242  WSKVDGAPLMESS----YKMLGNGRLVLENTTLEDAGLYECKAINLLGESSATMRLVVTV 297

Query: 1004 KKDI 1007
               +
Sbjct: 298  PPSV 301



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 5/69 (7%)

Query: 806 WYK-DGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAA 864
           W K DG P+  SS        G   L + +   EDAG Y  +A+N LGE+ +T  + V  
Sbjct: 242 WSKVDGAPLMESSYKM----LGNGRLVLENTTLEDAGLYECKAINLLGESSATMRLVVTV 297

Query: 865 RSTVTADLG 873
             +V+ D+G
Sbjct: 298 PPSVSIDIG 306



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 14/159 (8%)

Query: 633 VYPPPQFIV-PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
           V+  P+FI+ P KS+ A  G  +    +      P + I W ++G+SI          R 
Sbjct: 384 VFALPRFIISPPKSLKAEVGSDVILPCKAYG-SPPPLVITWHRHGKSIPQE-------RS 435

Query: 692 GYIS--LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQ 749
           G I   L ++ +   DSG Y C A S +G+ + +A+  +        ++      Q  + 
Sbjct: 436 GVIDGVLRLIDVTTADSGVYVCTATS-SGIFDAQAMTRLEVLENTAASANAAPAKQDGRS 494

Query: 750 LED--YSKYQHQESIEEQTSQRPQFIRPLQDLGELQEGR 786
           L +  ++K   +   E + S++ +    L D    + GR
Sbjct: 495 LTNSTHAKLDMKNGFEGKVSEKGKMTLKLDDKTSSKNGR 533



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 9/128 (7%)

Query: 2087 KIQELEKYERPKPIEEEQ--PGQRPVFLTALTS--LENLKEGDRAHFECRVEPINDPHLT 2142
            K Q+ EK ER   +  E+  PG       A+ S  L  +   D A F C    +  P L 
Sbjct: 182  KGQKGEKGERGIGVRGEKGAPGDTLSAPNAIVSPALITINASDTAVFHCAASGVPKPVLI 241

Query: 2143 IDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
                     + + ++       G   L +  T  ED+G Y CKA N LGE+  T  L V 
Sbjct: 242  WSKVDGAPLMESSYKM-----LGNGRLVLENTTLEDAGLYECKAINLLGESSATMRLVVT 296

Query: 2203 GHRNIILD 2210
               ++ +D
Sbjct: 297  VPPSVSID 304



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 7/93 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFH-NGKPLLTGSRVKTINDFGFVI 3616
            P    +P+ + ++ + +A F C    V    +   W   +G PL+  S  K + + G ++
Sbjct: 209  PNAIVSPALITINASDTAVFHCAASGVPKPVLI--WSKVDGAPLMESS-YKMLGN-GRLV 264

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            LE       DAGLY CKA N  GE++ + +L V
Sbjct: 265  LE--NTTLEDAGLYECKAINLLGESSATMRLVV 295



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 5/82 (6%)

Query: 2259 TAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVK 2318
            TA F C    V  P L          ++S+ +       G   L +++   EDAG Y  K
Sbjct: 225  TAVFHCAASGVPKPVLIWSKVDGAPLMESSYKM-----LGNGRLVLENTTLEDAGLYECK 279

Query: 2319 AINALGHCTSAISMTVTAKGSI 2340
            AIN LG  ++ + + VT   S+
Sbjct: 280  AINLLGESSATMRLVVTVPPSV 301



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 7/76 (9%)

Query: 1738 GDPKLRVEWLR-NGVPI-EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G PK  + W + +G P+ E+S ++      G   L ++    ED+G Y C+AIN LGE+ 
Sbjct: 234  GVPKPVLIWSKVDGAPLMESSYKM-----LGNGRLVLENTTLEDAGLYECKAINLLGESS 288

Query: 1796 TSSTLFVQSKASLQLE 1811
             +  L V    S+ ++
Sbjct: 289  ATMRLVVTVPPSVSID 304



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 16/34 (47%), Positives = 23/34 (67%)

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
            ED+G Y CKAIN LG++ +++RL V    S+  D
Sbjct: 271  EDAGLYECKAINLLGESSATMRLVVTVPPSVSID 304



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 7/60 (11%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P ++WTR    L        R     G +S+L  +    D G+Y C+ARN  G  I
Sbjct: 325 GFPLPEINWTRSAGQLPR-----RRVMTSGGQLSILAARAN--DSGDYFCSARNHIGSTI 377



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 5/72 (6%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            I    TA F C    V  P L         L+E S ++      G   + + +   ED G
Sbjct: 220  INASDTAVFHCAASGVPKPVLIWSKVDGAPLMESSYKM-----LGNGRLVLENTTLEDAG 274

Query: 2448 VYMCRASNLLGE 2459
            +Y C+A NLLGE
Sbjct: 275  LYECKAINLLGE 286



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 12/25 (48%), Positives = 19/25 (76%)

Query: 2710 DDSGIYTCKATNLLGEAVSTASIKI 2734
            +D+G+Y CKA NLLGE+ +T  + +
Sbjct: 271  EDAGLYECKAINLLGESSATMRLVV 295



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP   + +      EG  +    +    G P  +I W ++   +      TS    G +S
Sbjct: 298 PPSVSIDIGPTYVQEGDNVMLP-KCHVTGFPLPEINWTRSAGQLPRRRVMTS---GGQLS 353

Query: 696 LDMLSLNIQDSGEYTCRAVSATG--VAETKAVLHVTPRATI 734
           +  L+    DSG+Y C A +  G  +A T+ V+   PR  I
Sbjct: 354 I--LAARANDSGDYFCSARNHIGSTIARTQLVVFALPRFII 392



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 7/93 (7%)

Query: 3817 SDAPKEEPIVSTPPKFI-TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875
            S   + + +V   P+FI +  KS   E    V   C+      P L I W+R+GK +P  
Sbjct: 375  STIARTQLVVFALPRFIISPPKSLKAEVGSDVILPCKAYGSPPP-LVITWHRHGKSIPQ- 432

Query: 3876 HRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
             R   +  +    L ++ V   DSG Y+C A +
Sbjct: 433  ERSGVIDGV----LRLIDVTTADSGVYVCTATS 461


>SB_8388| Best HMM Match : ig (HMM E-Value=8.80001e-41)
          Length = 666

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 87/344 (25%), Positives = 138/344 (40%), Gaps = 33/344 (9%)

Query: 140 DEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTE 199
           DEG YTC A N  G AI    +  +                   +T+  +        +E
Sbjct: 353 DEGSYTCFASNAGGTAIAVTRLVVKVPVPVLIQRDDGTLTVKTGDTIVLRCL------SE 406

Query: 200 QSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRS 259
            S  +Q   Y NG    +  D K+    Y  +R  S  ++ T R VG  D    T   ++
Sbjct: 407 NSSPSQVTWYKNGRVLGNQGDAKL----YLTIR--SREDAGTYRCVGR-DGDRRTSKTKT 459

Query: 260 LGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
           +    PP I         Q+G D Q   Q+SG P+P V W K+GQ+L +  +   +T   
Sbjct: 460 IIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVR---MTVDV 516

Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRET 379
           + TL +R  + SDSG      +  +  +++   +      E  V D+R    T ++    
Sbjct: 517 NNTLTIRQAESSDSGR-----DLQSRVLLSHTQIQWYKGRELVVPDRR--IATSSRGHLV 569

Query: 380 EERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI-RDDYNH 438
              I+ S+      +  V  +   ++     F   V G P P+VTWF N  ++  DD  +
Sbjct: 570 INAIQQSDTG---YYTCVAVNTAGSDSVSVSFS--VQGNPKPKVTWFKNGYRVPLDDIKY 624

Query: 439 KILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           K    ++    L I  +   D+G+ TC A N  G   +   L V
Sbjct: 625 K----QTSADTLEIAGLVPQDTGIYTCRAENARGHDTWNITLVV 664



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 90/360 (25%), Positives = 128/360 (35%), Gaps = 58/360 (16%)

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            IR     D   +   A N GGTA     LVV+          VP         + V +G 
Sbjct: 346  IRVTTDRDEGSYTCFASNAGGTAIAVTRLVVKVP--------VPVLIQRDDGTLTVKTGD 397

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             + L      + P  V W KNG+         +L   G   L +     +D+G Y CV  
Sbjct: 398  TIVLRCLSENSSPSQVTWYKNGR---------VLGNQGDAKLYLTIRSREDAGTYRCVGR 448

Query: 4590 NSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGK 4649
            +  G+ R                K +T   N PP II     K   +G+ I+ +C++ G 
Sbjct: 449  D--GDRRTS--------------KTKTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGF 492

Query: 4650 PLPTVQWYK-GDKLIKPSKYFQMSRTAD-EYTLRISEAFPEDEG-DYKCVAYNS------ 4700
            P PTVQW K G +L       Q+  T D   TL I +A   D G D +     S      
Sbjct: 493  PKPTVQWTKDGQQLTS-----QVRMTVDVNNTLTIRQAESSDSGRDLQSRVLLSHTQIQW 547

Query: 4701 -AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE--------GQPAQFKTQITSKIKPT 4751
              GR  V    ++    +   +       D   Y                  +    KP 
Sbjct: 548  YKGRELVVPDRRIATSSRGHLVINAIQQSDTGYYTCVAVNTAGSDSVSVSFSVQGNPKPK 607

Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + W + G  +P   D     + +   L I     +DTG +TCRA  A G    +  LVV+
Sbjct: 608  VTWFKNGYRVP--LDDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARGHDTWNITLVVQ 665



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 64/281 (22%), Positives = 110/281 (39%), Gaps = 37/281 (13%)

Query: 4511 IVPPSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
            ++P S  ++A + V V  G  V L   V    P  V W K    + P +  ++ + + T+
Sbjct: 286  VLPDSPKVSADSLVEVLRGSPVTLTCMVDSVTPFRVQWTKGRDALGP-VLTRVGQVNVTH 344

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL 4629
            ++ +     +D G Y C A N+ G A      VV +P                P +I+  
Sbjct: 345  SIRVTT--DRDEGSYTCFASNAGGTAIAVTRLVVKVPV---------------PVLIQRD 387

Query: 4630 KDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
               + V  G  I   C         V WYK  +++             +  L ++    E
Sbjct: 388  DGTLTVKTGDTIVLRCLSENSSPSQVTWYKNGRVL---------GNQGDAKLYLTIRSRE 438

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            D G Y+CV  +   R +    + V +P     +   T  ++    +G+  Q   Q++   
Sbjct: 439  DAGTYRCVGRDGDRRTSKTKTIIVNEPPV---IIVDTSTKNF--QQGEDIQCACQVSGFP 493

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
            KPT+QW ++G  +  T   +M  + NN  L I      D+G
Sbjct: 494  KPTVQWTKDGQQL--TSQVRMTVDVNN-TLTIRQAESSDSG 531



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 9/122 (7%)

Query: 437 NHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER 496
           N ++L N+ G+  L +T  +  D+G   CV R+    T+    + V E      P  +  
Sbjct: 418 NGRVLGNQ-GDAKLYLTIRSREDAGTYRCVGRDGDRRTSKTKTIIVNE-----PPVIIVD 471

Query: 497 FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKAS 556
            ST N ++GE +    +  G P P + W KDG  +     + +  +   +TL I +A++S
Sbjct: 472 TSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMTVDVN---NTLTIRQAESS 528

Query: 557 DA 558
           D+
Sbjct: 529 DS 530



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 54/207 (26%), Positives = 91/207 (43%), Gaps = 23/207 (11%)

Query: 939  STLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSAN 998
            S  +V W K+GR +        +       LTI+S    DAG Y C   +  G   TS  
Sbjct: 409  SPSQVTWYKNGRVLGNQGDAKLY-------LTIRSR--EDAGTYRCVGRD--GDRRTSKT 457

Query: 999  LTIVTKKD--IIAESQHPGGL--EKIQYLEDASRYSKRTEEEVK----ITQKPRFLGPLK 1050
             TI+  +   II ++        E IQ     S + K T +  K    +T + R    + 
Sbjct: 458  KTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMTVDVN 517

Query: 1051 GTNKIVEGQSAHFEARVEPQSDLTMT-VEWYFNGKQITSANRIQTYHDFGYVALDIASVR 1109
             T  I + +S+     ++ +  L+ T ++WY   + +    RI T    G++ ++  +++
Sbjct: 518  NTLTIRQAESSDSGRDLQSRVLLSHTQIQWYKGRELVVPDRRIAT-SSRGHLVIN--AIQ 574

Query: 1110 AEDSGVYTVVARNAAGEAQLSASMTVE 1136
              D+G YT VA N AG   +S S +V+
Sbjct: 575  QSDTGYYTCVAVNTAGSDSVSVSFSVQ 601



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 6/68 (8%)

Query: 1738 GDPKLRVEWLRNG--VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G+PK +V W +NG  VP++      T  D     L +  + P+D+G YTCRA N  G   
Sbjct: 602  GNPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDT 657

Query: 1796 TSSTLFVQ 1803
             + TL VQ
Sbjct: 658  WNITLVVQ 665



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 4/58 (6%)

Query: 2802 DPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSAT 2858
            +P  K+ WF N   +P    +YK T   S  +L+I     +D+GIYTC+A N++G  T
Sbjct: 603  NPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAENARGHDT 657



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 16/121 (13%)

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS-TLNVREGE 506
           H++ +T  T  D G  TC A N  G      RL V    +V  P  ++R   TL V+ G+
Sbjct: 344 HSIRVT--TDRDEGSYTCFASNAGGTAIAVTRLVV----KVPVPVLIQRDDGTLTVKTGD 397

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            +VL   +  +   ++TW K+G         R+  + G + L +      DA  Y+C  +
Sbjct: 398 TIVLRCLSENSSPSQVTWYKNG---------RVLGNQGDAKLYLTIRSREDAGTYRCVGR 448

Query: 567 N 567
           +
Sbjct: 449 D 449



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 44/195 (22%), Positives = 77/195 (39%), Gaps = 22/195 (11%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  +     ++  +G+  +  C+V+G P P V W  + +Q+       + VN +    L 
Sbjct: 466 PVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMTVDVNNT----LT 521

Query: 452 ITNVTLSDSG------VV---TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST--- 499
           I     SDSG      V+   T +   K  E     R         +    +++  T   
Sbjct: 522 IRQAESSDSGRDLQSRVLLSHTQIQWYKGRELVVPDRRIATSSRGHLVINAIQQSDTGYY 581

Query: 500 ----LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
               +N    + V ++    G P P++TW K+G   +P  +++ +    A TL+I     
Sbjct: 582 TCVAVNTAGSDSVSVSFSVQGNPKPKVTWFKNGYR-VPLDDIK-YKQTSADTLEIAGLVP 639

Query: 556 SDAAWYQCTAQNVAG 570
            D   Y C A+N  G
Sbjct: 640 QDTGIYTCRAENARG 654



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/57 (43%), Positives = 30/57 (52%), Gaps = 12/57 (21%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYV-----ALDIIDLIAEDSGIYTCRAVNLVGTD 1528
            KV WFKNG  V       P+ D  Y       L+I  L+ +D+GIYTCRA N  G D
Sbjct: 607  KVTWFKNGYRV-------PLDDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARGHD 656



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDI 4169
            PPV +        ++GE  +  C+V+G PKP V W  +G  +   S+ ++T D      I
Sbjct: 465  PPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLT--SQVRMTVDVNNTLTI 522

Query: 4170 PKTRQYDTGK 4179
             +    D+G+
Sbjct: 523  RQAESSDSGR 532



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 4/57 (7%)

Query: 2938 KNDPDLKIEWYFNG-KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            + +P  K+ W+ NG +V     ++K TS     TL++  +  +D+GIYTC+A N RG
Sbjct: 601  QGNPKPKVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTCRAENARG 654



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 48/212 (22%), Positives = 86/212 (40%), Gaps = 17/212 (8%)

Query: 3444 LTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGE 3503
            L+    P+ +V WY NG+ L  G++       G   L ++    ED+G Y C   +    
Sbjct: 404  LSENSSPS-QVTWYKNGRVL--GNQ-------GDAKLYLTIRSREDAGTYRCVGRDGDRR 453

Query: 3504 AVTTASMKVQGKRNIILESQLPKGMEGT-IDKIAALEGY-SGTVDTLTPEAESGNPPEFT 3561
               T ++ V     II+++      +G  I     + G+   TV       +  +    T
Sbjct: 454  TSKTKTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMT 513

Query: 3562 TTPSDLILSENSSAHFECRLIP--VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEI 3619
               ++ +    + +    R +   V  S  +++W+  G+ L+   R    +  G ++  I
Sbjct: 514  VDVNNTLTIRQAESSDSGRDLQSRVLLSHTQIQWY-KGRELVVPDRRIATSSRGHLV--I 570

Query: 3620 GGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
              + Q D G YTC A N  G  +VS    V+G
Sbjct: 571  NAIQQSDTGYYTCVAVNTAGSDSVSVSFSVQG 602



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 4/55 (7%)

Query: 2671 DPNLKIEWFKNGVTLTTG-ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724
            +P  K+ WFKNG  +     + K T      TL I  L   D+GIYTC+A N  G
Sbjct: 603  NPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAENARG 654



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 1474 SNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
            S+ +++W+K G+ + +  R       G++ ++ I     D+G YTC AVN  G+D VS
Sbjct: 541  SHTQIQWYK-GRELVVPDRRIATSSRGHLVINAIQ--QSDTGYYTCVAVNTAGSDSVS 595



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 6/63 (9%)

Query: 3590 RVEWFHNGK--PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
            +V WF NG   PL      +T  D     LEI G+  +D G+YTC+A N  G  T +  L
Sbjct: 607  KVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTWNITL 662

Query: 3648 QVK 3650
             V+
Sbjct: 663  VVQ 665



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 36/162 (22%), Positives = 60/162 (37%), Gaps = 19/162 (11%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V  G  +  +C +       VQW KG   + P    ++ +    +++R++     DEG Y
Sbjct: 301  VLRGSPVTLTCMVDSVTPFRVQWTKGRDALGPV-LTRVGQVNVTHSIRVTT--DRDEGSY 357

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD--IVVYEGQPAQFKTQITSKIKPT 4751
             C A N+ G      +L V  P     +P L    D  + V  G     +    +     
Sbjct: 358  TCFASNAGGTAIAVTRLVVKVP-----VPVLIQRDDGTLTVKTGDTIVLRCLSENSSPSQ 412

Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            + W + G ++    D         A L +     ED GT+ C
Sbjct: 413  VTWYKNGRVLGNQGD---------AKLYLTIRSREDAGTYRC 445



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 45/246 (18%), Positives = 90/246 (36%), Gaps = 17/246 (6%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            +V  P   + Q    T+    G     R   +     ++ WY+NG++L +          
Sbjct: 375  VVKVPVPVLIQRDDGTLTVKTGDTIVLRCLSENSSPSQVTWYKNGRVLGN---------Q 425

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALT 3944
            G   L +     ED+G Y C    D     +K        P +I+ +   +  ++ E + 
Sbjct: 426  GDAKLYLTIRSREDAGTYRCVG-RDGDRRTSKTKTIIVNEPPVIIVDTSTKNFQQGEDI- 483

Query: 3945 QMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQL-APVGDP 4003
            Q    +  +         D   +  +   R    + +  ++ + E++     L + V   
Sbjct: 484  QCACQVSGFPKPTVQWTKDGQQLTSQV--RMTVDVNNTLTIRQAESSDSGRDLQSRVLLS 541

Query: 4004 NMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
            + +++W+  G+ L+  +R       G++ +N   +   D+G Y C A N  G D      
Sbjct: 542  HTQIQWY-KGRELVVPDRRIATSSRGHLVINA--IQQSDTGYYTCVAVNTAGSDSVSVSF 598

Query: 4064 KTTGKP 4069
               G P
Sbjct: 599  SVQGNP 604



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718
           G+P  K+ W KNG  +          +    +L++  L  QD+G YTCRA +A G
Sbjct: 602 GNPKPKVTWFKNGYRVPLDD--IKYKQTSADTLEIAGLVPQDTGIYTCRAENARG 654



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 13/108 (12%)

Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATG---SRVHTLN 3748
            P+ P+ + +    ++V  G PV   C V+ V     R+ W   GR  A G   +RV  +N
Sbjct: 288  PDSPKVSAD--SLVEVLRGSPVTLTCMVDSV--TPFRVQWT-KGRD-ALGPVLTRVGQVN 341

Query: 3749 DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLE 3796
                I +  D    RD G YTC A+N  G+A    ++       ++++
Sbjct: 342  VTHSIRVTTD----RDEGSYTCFASNAGGTAIAVTRLVVKVPVPVLIQ 385



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 8/61 (13%)

Query: 95  LRGNPTPVVSWTRK--KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQY 152
           ++GNP P V+W +   + PL +     ++Y + + D +L I  + P D G YTC A N  
Sbjct: 600 VQGNPKPKVTWFKNGYRVPLDD-----IKYKQTSAD-TLEIAGLVPQDTGIYTCRAENAR 653

Query: 153 G 153
           G
Sbjct: 654 G 654



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 4/63 (6%)

Query: 3858 DPKLRIEWYRNGKLLPSGH-RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTK 3916
            +PK ++ W++NG  +P    +Y+        +L+I  +  +D+G Y CRA N  G D   
Sbjct: 603  NPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAENARGHDTWN 659

Query: 3917 ATI 3919
             T+
Sbjct: 660  ITL 662



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 12/167 (7%)

Query: 704 QDSGEYTCRAVSATG-VAETKAVLHVTPRATIERTS----QHPETLQYIQQLEDYSK--Y 756
           +D+G Y C         ++TK ++   P   I  TS    Q  E +Q   Q+  + K   
Sbjct: 438 EDAGTYRCVGRDGDRRTSKTKTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTV 497

Query: 757 QHQESIEEQTSQRPQFIRPLQDLGELQ-EGRNAHFEAQLTPVSDPTMRVEWYKDGRPITA 815
           Q  +  ++ TSQ    +     L   Q E  ++  + Q   +   T +++WYK GR +  
Sbjct: 498 QWTKDGQQLTSQVRMTVDVNNTLTIRQAESSDSGRDLQSRVLLSHT-QIQWYK-GRELVV 555

Query: 816 SSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
             R  +  + G++ +N   ++  D G YT  AVN  G    + S  V
Sbjct: 556 PDRRIATSSRGHLVINA--IQQSDTGYYTCVAVNTAGSDSVSVSFSV 600



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 2/65 (3%)

Query: 1338 GDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
            G+   +V WF NG  +            D   L++  + P+D+G+YTC+A N  G    +
Sbjct: 602  GNPKPKVTWFKNGYRVPLDDIKYKQTSAD--TLEIAGLVPQDTGIYTCRAENARGHDTWN 659

Query: 1398 CALRV 1402
              L V
Sbjct: 660  ITLVV 664



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 17/61 (27%), Positives = 31/61 (50%), Gaps = 3/61 (4%)

Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +I+W+K    +    R+ ++    LV   IN+++  D+G YTC A N  G    + S  +
Sbjct: 544  QIQWYKGRELVVPDRRIATSSRGHLV---INAIQQSDTGYYTCVAVNTAGSDSVSVSFSV 600

Query: 2735 E 2735
            +
Sbjct: 601  Q 601



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 6/67 (8%)

Query: 1873 DPNMRVEWYFNG-KVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVS 1930
            +P  +V W+ NG +V     +Y+ TS D     L+I  +  +D+G YTC+A N  G    
Sbjct: 603  NPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTW 658

Query: 1931 SIRLNVQ 1937
            +I L VQ
Sbjct: 659  NITLVVQ 665



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 46/209 (22%), Positives = 87/209 (41%), Gaps = 21/209 (10%)

Query: 2005 NDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            N    +V WY NGR +  G++       G   L +     ED GTY C   +       T
Sbjct: 407  NSSPSQVTWYKNGRVL--GNQ-------GDAKLYLTIRSREDAGTYRCVGRDGDRRTSKT 457

Query: 2065 SSVKVDAKSGLYLDTLDE--QRLKKIQ-ELEKYERPKP-IEEEQPGQRPVFLTALTSLEN 2120
             ++ V+    + +DT  +  Q+ + IQ   +    PKP ++  + GQ+      +T   N
Sbjct: 458  KTIIVNEPPVIIVDTSTKNFQQGEDIQCACQVSGFPKPTVQWTKDGQQLTSQVRMTVDVN 517

Query: 2121 ----LKEGDRAHFECRVEP-INDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTY 2175
                +++ + +     ++  +   H  I W+  G+++    R   T   G++ ++ +   
Sbjct: 518  NTLTIRQAESSDSGRDLQSRVLLSHTQIQWY-KGRELVVPDRRIATSSRGHLVINAIQQ- 575

Query: 2176 AEDSGTYMCKATNKLGEAVNTCTLKVAGH 2204
              D+G Y C A N  G    + +  V G+
Sbjct: 576  -SDTGYYTCVAVNTAGSDSVSVSFSVQGN 603



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 4/56 (7%)

Query: 2536 GDPSLRFEWYINGVELKMGS-RFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G+P  +  W+ NG  + +   +++ T      TL+I  +V  D G+Y C+A N  G
Sbjct: 602  GNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAENARG 654



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 3/61 (4%)

Query: 1877 RVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
            +++WY   +++    R  TS+      L I  +   D+G YTC A+N  G    S+  +V
Sbjct: 544  QIQWYKGRELVVPDRRIATSSR---GHLVINAIQQSDTGYYTCVAVNTAGSDSVSVSFSV 600

Query: 1937 Q 1937
            Q
Sbjct: 601  Q 601



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 4/51 (7%)

Query: 1610 KVEWYHNNKPLKSGS-RFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            KV W+ N   +     ++ +T+      L+I   +P+D+G YTCRA NA G
Sbjct: 607  KVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTCRAENARG 654



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 12/62 (19%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYV-----AMNFGWVYPEDSGEYLCRATNLYG 4055
            G+P  KV WF NG  +       P+ D  Y       +    + P+D+G Y CRA N  G
Sbjct: 602  GNPKPKVTWFKNGYRV-------PLDDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARG 654

Query: 4056 MD 4057
             D
Sbjct: 655  HD 656



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 6/67 (8%)

Query: 3449 DPNLKVEWYWNGKSLKAGS-RFR-TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVT 3506
            +P  KV W+ NG  +     +++ T  D     LEI+   P+D+G Y CRA N  G    
Sbjct: 603  NPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTW 658

Query: 3507 TASMKVQ 3513
              ++ VQ
Sbjct: 659  NITLVVQ 665



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 3178 DPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
            +P  K+ W+ NG   P+      +T +D     L+IA     D+G Y CRA N  G D  
Sbjct: 603  NPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTW 658

Query: 3236 RATI 3239
              T+
Sbjct: 659  NITL 662



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 2541 RFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            + +WY  G EL +  R   T   G +   IN++  +D G Y C A+N AG
Sbjct: 544  QIQWY-KGRELVVPDRRIATSSRGHLV--INAIQQSDTGYYTCVAVNTAG 590


>SB_51089| Best HMM Match : I-set (HMM E-Value=1.4e-38)
          Length = 1334

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 66/200 (33%), Positives = 88/200 (44%), Gaps = 20/200 (10%)

Query: 382  RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            R+EI    +AP        R +  G+    DC   G P PEV W +N   I      K+L
Sbjct: 1064 RVEILVDLIAPVIQTKSLPRTLVFGQTLLLDCEAKGSPQPEVKWMLNGNDI---IFGKVL 1120

Query: 442  VNESGNHALMITNVTLSDS--GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
             N S    L +  V   D+  G  TC A N+        ++ + E  Q++ P  + R ST
Sbjct: 1121 ANGS----LKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTP--LTR-ST 1173

Query: 500  LNVREGEPVVLNARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
              +R G+  VL   A G P PRI W +KDG   IP PE RI ++     L IP A + DA
Sbjct: 1174 AVLR-GKSAVLTCYATGDPMPRIAWSKKDGT--IP-PE-RIRSNN--HVLLIPHATSRDA 1226

Query: 559  AWYQCTAQNVAGSTATRARL 578
              Y C A N      +   L
Sbjct: 1227 GTYSCIATNYIKEVTSETNL 1246



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 48/186 (25%), Positives = 76/186 (40%), Gaps = 26/186 (13%)

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            GQ + LD +  G+   +V W+ NG  +   I  K+L  +G+  +  +E      G Y C 
Sbjct: 1088 GQTLLLDCEAKGSPQPEVKWMLNGNDI---IFGKVLA-NGSLKVEKVENDDNFEGTYTCR 1143

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPL-KDKIVAEGQAIEFSCKI 4646
            A N    AR   +  +                +  P+I+ PL +   V  G++   +C  
Sbjct: 1144 ASNRVSTARSSTQVTI----------------HEGPQILTPLTRSTAVLRGKSAVLTCYA 1187

Query: 4647 VGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
             G P+P + W K D  I P +       ++ + L I  A   D G Y C+A N    VT 
Sbjct: 1188 TGDPMPRIAWSKKDGTIPPERI-----RSNNHVLLIPHATSRDAGTYSCIATNYIKEVTS 1242

Query: 4707 AAKLKV 4712
               L +
Sbjct: 1243 ETNLTI 1248



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 49/181 (27%), Positives = 75/181 (41%), Gaps = 21/181 (11%)

Query: 4637 GQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKYFQMSRTADEYTLRISEAFPED--EGDY 4693
            GQ +   C+  G P P V+W   G+ +I         +     +L++ +   +D  EG Y
Sbjct: 1088 GQTLLLDCEAKGSPQPEVKWMLNGNDII-------FGKVLANGSLKVEKVENDDNFEGTY 1140

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL-RDIVVYEGQPAQFKTQITSKIKPTI 4752
             C A N       + ++ + +  Q      LTPL R   V  G+ A      T    P I
Sbjct: 1141 TCRASNRVSTARSSTQVTIHEGPQI-----LTPLTRSTAVLRGKSAVLTCYATGDPMPRI 1195

Query: 4753 QWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKS 4812
             W ++   IP     + I   NN VLLI +    D GT++C AT    +V +   L +  
Sbjct: 1196 AWSKKDGTIPP----ERIRS-NNHVLLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIG 1250

Query: 4813 K 4813
            K
Sbjct: 1251 K 1251



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 10/119 (8%)

Query: 367  RSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWF 426
            R+     T +  T+  I    + L P    + +   V  GK     C  TG P P + W 
Sbjct: 1143 RASNRVSTARSSTQVTIHEGPQILTP----LTRSTAVLRGKSAVLTCYATGDPMPRIAWS 1198

Query: 427  INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEK 485
              D  I  +   +I    S NH L+I + T  D+G  +C+A N   E   +  L +I K
Sbjct: 1199 KKDGTIPPE---RI---RSNNHVLLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGK 1251



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 49/192 (25%), Positives = 78/192 (40%), Gaps = 19/192 (9%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEIS 3135
            G     ++W  NG  I        V A G + +E +       GTY+CRA+N+   A  S
Sbjct: 1099 GSPQPEVKWMLNGNDIIFGK----VLANGSLKVEKVENDDNFEGTYTCRASNRVSTARSS 1154

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
             ++     +  + P+  T +     +  G+SA   C      DP  +I W      +   
Sbjct: 1155 TQV-----TIHEGPQILTPLTRSTAVLRGKSAVLTC--YATGDPMPRIAWSKKDGTI-PP 1206

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTRATINCYGK---GGVYLESL 3252
             RI++ +     VL I +  + D+G Y C A N   E  +   +   GK   GG     +
Sbjct: 1207 ERIRSNNH----VLLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKMEGGGSCSVPV 1262

Query: 3253 QPDSLAKIRELE 3264
            +  SL +  ELE
Sbjct: 1263 RMSSLPEHGELE 1274



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 6/121 (4%)

Query: 1165 PMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGS 1224
            P  ++E +       +Q  S P  +  G+ + L+C  E  G P   V+W  NG  +  G 
Sbjct: 1061 PCLRVEILVDLIAPVIQTKSLPRTLVFGQTLLLDC--EAKGSPQPEVKWMLNGNDIIFGK 1118

Query: 1225 RFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQA 1284
                    G + ++ +       G YT RA N + +A +S  V + E   I+T      A
Sbjct: 1119 VLAN----GSLKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTPLTRSTA 1174

Query: 1285 I 1285
            +
Sbjct: 1175 V 1175



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 46/196 (23%), Positives = 72/196 (36%), Gaps = 23/196 (11%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I TK +    VF  +    + E  G P P +KW      + N  D           L 
Sbjct: 1074 PVIQTKSLPRTLVFG-QTLLLDCEAKGSPQPEVKW------MLNGNDIIFGKVLANGSLK 1126

Query: 4470 IRQVFVEDS--AVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            + +V  +D+    +   A NR  TA+ S  + + E          P   T   ++  V  
Sbjct: 1127 VEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEG---------PQILTPLTRSTAVLR 1177

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G+   L    TG     + W K    + P+   +I      + LLI  A  +D+G Y C+
Sbjct: 1178 GKSAVLTCYATGDPMPRIAWSKKDGTIPPE---RI--RSNNHVLLIPHATSRDAGTYSCI 1232

Query: 4588 AINSAGEARCDAECVV 4603
            A N   E   +    +
Sbjct: 1233 ATNYIKEVTSETNLTI 1248



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 13/99 (13%)

Query: 2641 APIFTTHLKSYDK-LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            AP+  T  KS  + LV GQ + L+   E +  P  +++W  NG  +  G  L +      
Sbjct: 1073 APVIQT--KSLPRTLVFGQTLLLDC--EAKGSPQPEVKWMLNGNDIIFGKVLANG----- 1123

Query: 2700 VTLSINSLRNDDS--GIYTCKATNLLGEAVSTASIKIED 2736
             +L +  + NDD+  G YTC+A+N +  A S+  + I +
Sbjct: 1124 -SLKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHE 1161



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 9/140 (6%)

Query: 1802 VQSKASLQLES-QHESALQKIQQLEDSSRYQR-REDVEVAVNQAPRFITQLNGPTKLSEG 1859
            V +  SL++E  +++   +       S+R    R   +V +++ P+ +T L   T +  G
Sbjct: 1119 VLANGSLKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTPLTRSTAVLRG 1178

Query: 1860 QSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTC 1919
            +SA   C      DP  R+ W      +    R R++N      L I      D+G Y+C
Sbjct: 1179 KSAVLTCYAT--GDPMPRIAWSKKDGTIPP-ERIRSNNH----VLLIPHATSRDAGTYSC 1231

Query: 1920 KAINNLGQAVSSIRLNVQSK 1939
             A N + +  S   L +  K
Sbjct: 1232 IATNYIKEVTSETNLTIIGK 1251



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 7/98 (7%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P+  TP+    ++  G  A         GD   R+ W K    +    RI +  +     
Sbjct: 1163 PQILTPLTRSTAVLRGKSAVLTCYAT--GDPMPRIAWSKKDGTIPPE-RIRSNNH----V 1215

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
            L I   T  DAG Y+C A N I + T+  NLTI+ K +
Sbjct: 1216 LLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKME 1253



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 10/119 (8%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            VE+ V+     I   + P  L  GQ+   +C  +  P P   V+W  NG  +  G     
Sbjct: 1065 VEILVDLIAPVIQTKSLPRTLVFGQTLLLDCEAKGSPQPE--VKWMLNGNDIIFGKVLAN 1122

Query: 1896 SNDFGFAALDILTVYGEDS--GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952
             +      L +  V  +D+  G YTC+A N +  A SS ++ +     I+      +A+
Sbjct: 1123 GS------LKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTPLTRSTAV 1175



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 6/79 (7%)

Query: 2923 LVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSG 2982
            LV GQ L L+   E K  P  +++W  NG  +  G   K+ ++ G + ++ V+  +   G
Sbjct: 1085 LVFGQTLLLD--CEAKGSPQPEVKWMLNGNDIIFG---KVLAN-GSLKVEKVENDDNFEG 1138

Query: 2983 IYTCKAYNKRGEAFTSSTV 3001
             YTC+A N+   A +S+ V
Sbjct: 1139 TYTCRASNRVSTARSSTQV 1157



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 14/34 (41%), Positives = 19/34 (55%)

Query: 4121 TVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154
            T+  G+     C   G P+P V W+LNGN I+ G
Sbjct: 1084 TLVFGQTLLLDCEAKGSPQPEVKWMLNGNDIIFG 1117



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 39/132 (29%), Positives = 54/132 (40%), Gaps = 14/132 (10%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            ST++ + E     P+ +T L  +T V  GK+A   C      DP  RI +      +   
Sbjct: 1154 STQVTIHEG----PQILTPLTRSTAVLRGKSAVLTCYA--TGDPMPRIAWSKKDGTIPPE 1207

Query: 2289 ARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK---GSIISESQ 2345
             R        +V L I H    DAG YS  A N +   TS  ++T+  K   G   S   
Sbjct: 1208 -RIRSN---NHVLL-IPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKMEGGGSCSVPV 1262

Query: 2346 RPEGLEKIRELE 2357
            R   L +  ELE
Sbjct: 1263 RMSSLPEHGELE 1274



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 7/98 (7%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P  + PL+    V  GK+  L C     GDP  R+ W     ++    R ++        
Sbjct: 1163 PQILTPLTRSTAVLRGKSAVLTCYAT--GDPMPRIAWSKKDGTIPP-ERIRSNNH----V 1215

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSD 1274
            L I HATS D G Y+  A N++    +   + +I + +
Sbjct: 1216 LLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKME 1253



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 6/73 (8%)

Query: 661  EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVS--ATG 718
            E  G P  +++W+ NG  I     F  +   G + ++ +  +    G YTCRA +  +T 
Sbjct: 1096 EAKGSPQPEVKWMLNGNDI----IFGKVLANGSLKVEKVENDDNFEGTYTCRASNRVSTA 1151

Query: 719  VAETKAVLHVTPR 731
             + T+  +H  P+
Sbjct: 1152 RSSTQVTIHEGPQ 1164



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/128 (21%), Positives = 47/128 (36%), Gaps = 9/128 (7%)

Query: 2334 VTAKGSI-ISESQRPEGLEKIRELESAEPFKRPEIPEPVT-RQRPVFTQPLQNIDNIQEG 2391
            V A GS+ + + +  +  E      ++           VT  + P    PL     +  G
Sbjct: 1119 VLANGSLKVEKVENDDNFEGTYTCRASNRVSTARSSTQVTIHEGPQILTPLTRSTAVLRG 1178

Query: 2392 QTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMC 2451
            ++A   C     GDP  ++ W + +  I      +  H      + I H    D G Y C
Sbjct: 1179 KSAVLTC--YATGDPMPRIAWSKKDGTIPPERIRSNNH-----VLLIPHATSRDAGTYSC 1231

Query: 2452 RASNLLGE 2459
             A+N + E
Sbjct: 1232 IATNYIKE 1239



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 5/78 (6%)

Query: 265  PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
            P  +    R++ +  G  A      +G+P PR+ W K    +      E I ++NH  L 
Sbjct: 1163 PQILTPLTRSTAVLRGKSAVLTCYATGDPMPRIAWSKKDGTI----PPERIRSNNHVLL- 1217

Query: 325  VRNTQKSDSGHYTLLAEN 342
            + +    D+G Y+ +A N
Sbjct: 1218 IPHATSRDAGTYSCIATN 1235



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 8/133 (6%)

Query: 3280 EPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGI 3339
            E P+ +T +   T ++ G+SA          DP  ++ W      +P   R R+ +    
Sbjct: 1161 EGPQILTPLTRSTAVLRGKSAVLTC--YATGDPMPRIAWSKKDGTIPP-ERIRSNNH--- 1214

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKENLILDSQLPRGMEGGLEKLQT 3399
             +L I +    ++G Y C+ATN +   +++ NL    K        +P  M   L +   
Sbjct: 1215 -VLLIPHATSRDAGTYSCIATNYIKEVTSETNLTIIGKMEGGGSCSVPVRM-SSLPEHGE 1272

Query: 3400 LEDSMVRRKDTSV 3412
            LE      KDT +
Sbjct: 1273 LEPGSHTAKDTDI 1285



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            GDP  RI W           R+ + N      L I +  +RDAG Y+C ATN     T+ 
Sbjct: 1189 GDPMPRIAWSKKDGTIPP-ERIRSNNH----VLLIPHATSRDAGTYSCIATNYIKEVTSE 1243

Query: 3783 AKITCSAKRDIVLESQLPQGMSG-EKIKELERG 3814
              +T   K +      +P  MS   +  ELE G
Sbjct: 1244 TNLTIIGKMEGGGSCSVPVRMSSLPEHGELEPG 1276


>SB_31697| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 518

 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 42/116 (36%), Positives = 59/116 (50%), Gaps = 1/116 (0%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ-MSRTADEYTL 4680
            PP   + LKD  + EG A  F C+I G P P V+WY+  +L+K  K    +    D   L
Sbjct: 26   PPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKL 85

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
             I+E    D G+YK VA N  G+V+ +AKL +  P  +D+  A     DI   E +
Sbjct: 86   IITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPSDDESASDAESDISEEESE 141



 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 2/121 (1%)

Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN-H 320
           P  PP   QK ++ K+ EG+ A+F+ Q++GNP P V W++NG+ L    +   +   N +
Sbjct: 23  PKGPPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDN 82

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETE 380
             L +   + +D+G Y ++AEN +G +  S  L +  P  S   +  S   +D  + E+E
Sbjct: 83  CKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPS-DDESASDAESDISEEESE 141

Query: 381 E 381
           +
Sbjct: 142 D 142



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 1/97 (1%)

Query: 4407 PSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQ-IHTFSTK 4465
            P  PP+F +K++ C++ E   ARFE +  G P P ++WYR    +K       ++  +  
Sbjct: 23   PKGPPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDN 82

Query: 4466 SILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEE 4502
              LII +    D+  +  VAENR G   CSA L++ +
Sbjct: 83   CKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIIND 119



 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 32/88 (36%), Positives = 49/88 (55%), Gaps = 1/88 (1%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP+F+Q  K+ +  +G  A+FE ++ GNP P V W R    L EC + +  Y+E   +  
Sbjct: 26  PPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDE-NDNCK 84

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICS 158
           L+I +    D GEY   A N++G+  CS
Sbjct: 85  LIITEGKHADAGEYKVVAENRHGKVSCS 112



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 29/89 (32%), Positives = 48/89 (53%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F +  +D  + EG   RF+C++TG P PEV W+ N   +++      L +E+ N  L+
Sbjct: 27  PVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKLI 86

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRL 480
           IT    +D+G    VA N+ G+ +   +L
Sbjct: 87  ITEGKHADAGEYKVVAENRHGKVSCSAKL 115



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 1/129 (0%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL-EEDGTYTL 4571
            PP F    ++  +  G   R + ++TG    +V W +NG+ ++   +   L +E+    L
Sbjct: 26   PPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKL 85

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
            +I E    D+G+Y+ VA N  G+  C A+ +++ P   D        ++   E  E    
Sbjct: 86   IITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPSDDESASDAESDISEEESEDEDK 145

Query: 4632 KIVAEGQAI 4640
             +V +  AI
Sbjct: 146  DVVLKSDAI 154



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 4727 LRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYE 4785
            L+D  + EG  A+F+ QIT   +P ++W R G L+ E      ++ E +N  L+I     
Sbjct: 33   LKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKLIITEGKH 92

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
             D G +   A    G+V  SAKL++
Sbjct: 93   ADAGEYKVVAENRHGKVSCSAKLII 117



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 7/149 (4%)

Query: 1701 SAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            ++ D+V    PVF   +KD ++ E  AA FE ++   G+P+  VEW RNG  ++   +LT
Sbjct: 17   NSTDDVPKGPPVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLT 74

Query: 1761 TMHDFG-YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQ 1819
             ++D      L +      D+G Y   A N  G+   S+ L +       + S  ESA  
Sbjct: 75   FLYDENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIIND----PVPSDDESASD 130

Query: 1820 KIQQLEDSSRYQRREDVEVAVNQAPRFIT 1848
                + +       +DV +  +   ++ T
Sbjct: 131  AESDISEEESEDEDKDVVLKSDAITKYYT 159



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 14/129 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG-FV 3887
            PP F  ++K   + E    RFEC++    +P+  +EWYRNG+LL    +   +YD     
Sbjct: 26   PPVFKQKLKDCKIIEGSAARFECQITGNPEPE--VEWYRNGELLKECKQLTFLYDENDNC 83

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKRSEALTQME 3947
             L I      D+GEY   A N  G+      +SC     +I+ + VP      E+ +  E
Sbjct: 84   KLIITEGKHADAGEYKVVAENRHGK------VSCS--AKLIINDPVP---SDDESASDAE 132

Query: 3948 ATIKKYTSE 3956
            + I +  SE
Sbjct: 133  SDISEEESE 141



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 4/92 (4%)

Query: 2369 EPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428
            + V +  PVF Q L++   I EG  A F+C++   G+P  +VEW+RN +L+++  ++T  
Sbjct: 20   DDVPKGPPVFKQKLKDC-KIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFL 76

Query: 2429 HDFG-YVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +D      + I+  +  D G Y   A N  G+
Sbjct: 77   YDENDNCKLIITEGKHADAGEYKVVAENRHGK 108



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 6/133 (4%)

Query: 1170 EEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTY 1229
            +++ K  PVF Q L +   + EG     EC++   G+P   VEW+ NG  +    +    
Sbjct: 20   DDVPKGPPVFKQKLKDCK-IIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFL 76

Query: 1230 YDFG-FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQI 1288
            YD      L I     AD GEY V A N  G    SA  ++I    + +D ++    E  
Sbjct: 77   YDENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSA--KLIINDPVPSDDESASDAESD 134

Query: 1289 QLLEDAARRTKQV 1301
               E++    K V
Sbjct: 135  ISEEESEDEDKDV 147



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 43/143 (30%), Positives = 67/143 (46%), Gaps = 16/143 (11%)

Query: 3545 VDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGS 3604
            V   T +   G PP F     D  + E S+A FEC++    +    VEW+ NG+ L    
Sbjct: 15   VGNSTDDVPKG-PPVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECK 71

Query: 3605 RVKTI---NDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL 3661
            ++  +   ND   +I+  G     DAG Y   A NRHG+ + S KL       II +P +
Sbjct: 72   QLTFLYDENDNCKLIITEGK--HADAGEYKVVAENRHGKVSCSAKL-------IINDP-V 121

Query: 3662 PSHFKSGTESIQKLEETLHKREE 3684
            PS  +S +++   + E   + E+
Sbjct: 122  PSDDESASDAESDISEEESEDED 144



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 4/103 (3%)

Query: 3037 GQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHR 3096
            G   DD    PP F    KD   I EG  A +E  +  TG+    +EW+ NG+ ++   +
Sbjct: 16   GNSTDDVPKGPPVFKQKLKDC-KIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQ 72

Query: 3097 IRTVY-AFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKL 3138
            +  +Y       L I   K  D+G Y   A N+ G+   S KL
Sbjct: 73   LTFLYDENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKL 115



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 4/93 (4%)

Query: 3281 PPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFG-I 3339
            PP F  +++D  K++EG +A FE ++    +P+ +VEW+ NG+ L    +    +D    
Sbjct: 26   PPVFKQKLKDC-KIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFLYDENDN 82

Query: 3340 VILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              L I      ++GEY+ VA N+ G+ S  A L
Sbjct: 83   CKLIITEGKHADAGEYKVVAENRHGKVSCSAKL 115



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 1043 PRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQ-TYHDFGYV 1101
            P F   LK   KI+EG +A FE ++    +    VEWY NG+ +    ++   Y +    
Sbjct: 27   PVFKQKLKDC-KIIEGSAARFECQITGNPE--PEVEWYRNGELLKECKQLTFLYDENDNC 83

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSS 1145
             L I   +  D+G Y VVA N  G+   SA + +      D  S
Sbjct: 84   KLIITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPSDDES 127



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 5/99 (5%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            PK  PP F  +L+    + EG  A FECQ+    +P   +E+Y NG+ L+   +    +D
Sbjct: 23   PK-GPPVFKQKLKDCK-IIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFLYD 78

Query: 2297 FG-YVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
                  L I      DAGEY V A N  G  + +  + +
Sbjct: 79   ENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKLII 117



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 42/178 (23%), Positives = 77/178 (43%), Gaps = 12/178 (6%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAY-EFDYVA 1369
            P F + L + + +EG+    EC++   G+    VEW+ NG+ +K   +    Y E D   
Sbjct: 27   PVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFLYDENDNCK 84

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSR 1429
            L +      D+G Y   A N+ G+   SC+ +      LI+    PS  E     E    
Sbjct: 85   LIITEGKHADAGEYKVVAENRHGK--VSCSAK------LIINDPVPSDDESASDAESDIS 136

Query: 1430 YKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECK-LEPVTDSNLKVEWFKNGQP 1486
             ++++  D+ V +K   +T+  +I++ +        CK +   T      ++ K  +P
Sbjct: 137  EEESEDEDKDVVLKSDAITKYYTIKDELGKGRFGVVCKCVNKKTGKQFAAKFIKCSKP 194



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 15/160 (9%)

Query: 3688 EDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTL 3747
            +D    PP F  ++KD   + EG    F+C++   G+P   ++W+ NG       ++  L
Sbjct: 20   DDVPKGPPVFKQKLKD-CKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFL 76

Query: 3748 NDFGF-IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGE 3806
             D      L I      DAGEY   A N+ G      K++CSAK  +++   +P     E
Sbjct: 77   YDENDNCKLIITEGKHADAGEYKVVAENRHG------KVSCSAK--LIINDPVPS--DDE 126

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEG 3846
               + E   IS+   E+       K     K +T+++  G
Sbjct: 127  SASDAE-SDISEEESEDEDKDVVLKSDAITKYYTIKDELG 165



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 20/53 (37%), Positives = 27/53 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            PPVF        + EG  ARF C++TG+P+P V W  NG  +    +    YD
Sbjct: 26   PPVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYD 78



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            V + P    Q     K+ EG +A +EC+I   P+P   VEWY NG++L+   +     D 
Sbjct: 22   VPKGPPVFKQKLKDCKIIEGSAARFECQITGNPEP--EVEWYRNGELLKECKQLTFLYDE 79

Query: 1900 GFAALDILTV-YGEDSGEYTCKAINNLGQAVSSIRL 1934
                  I+T     D+GEY   A N  G+   S +L
Sbjct: 80   NDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKL 115



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 26/92 (28%), Positives = 50/92 (54%), Gaps = 5/92 (5%)

Query: 3142 DKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTV 3201
            D  KG  P F   +++ + + +G +A FEC +    +P+ ++EWY NG+ ++   ++  +
Sbjct: 21   DVPKGP-PVFKQKLKDCK-IIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFL 76

Query: 3202 SDFG-FVVLDIAYTQNHDSGEYVCRAYNKYGE 3232
             D      L I   ++ D+GEY   A N++G+
Sbjct: 77   YDENDNCKLIITEGKHADAGEYKVVAENRHGK 108



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 4/87 (4%)

Query: 3970 KQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFG 4029
            K PP F  +++    ++E    +FECQ+   G+P  +VEW+ NG+ L    + T +YD  
Sbjct: 24   KGPPVFKQKLKD-CKIIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFLYDEN 80

Query: 4030 -YVAMNFGWVYPEDSGEYLCRATNLYG 4055
                +        D+GEY   A N +G
Sbjct: 81   DNCKLIITEGKHADAGEYKVVAENRHG 107



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 4/96 (4%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG-LV 2700
            P+F   LK   K++EG     E Q+    +P  ++EW++NG  L    +L   +D     
Sbjct: 27   PVFKQKLKDC-KIIEGSAARFECQITGNPEP--EVEWYRNGELLKECKQLTFLYDENDNC 83

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
             L I   ++ D+G Y   A N  G+   +A + I D
Sbjct: 84   KLIITEGKHADAGEYKVVAENRHGKVSCSAKLIIND 119



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 5/137 (3%)

Query: 622 RPYIPPGEEDRVYP-PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIE 680
           RP +     D V   PP F   LK    +EG    FE +I   G+P  ++EW +NG+ ++
Sbjct: 11  RPNVVGNSTDDVPKGPPVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLK 68

Query: 681 ASSRFTSIF-RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT-PRATIERTS 738
              + T ++       L +      D+GEY   A +  G     A L +  P  + + ++
Sbjct: 69  ECKQLTFLYDENDNCKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIINDPVPSDDESA 128

Query: 739 QHPETLQYIQQLEDYSK 755
              E+    ++ ED  K
Sbjct: 129 SDAESDISEEESEDEDK 145



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 4/92 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFG-FV 3478
            PVF   L + + + EG  A FE ++T   +P  +VEWY NG+ LK   +     D     
Sbjct: 27   PVFKQKLKDCKII-EGSAARFECQITGNPEP--EVEWYRNGELLKECKQLTFLYDENDNC 83

Query: 3479 ILEISPTYPEDSGEYLCRAYNNYGEAVTTASM 3510
             L I+     D+GEY   A N +G+   +A +
Sbjct: 84   KLIITEGKHADAGEYKVVAENRHGKVSCSAKL 115



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 21/89 (23%), Positives = 38/89 (42%), Gaps = 1/89 (1%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELR-IHTDGGASTLD 549
           P F ++     + EG       +  G P P + W ++G  +    +L  ++ +     L 
Sbjct: 27  PVFKQKLKDCKIIEGSAARFECQITGNPEPEVEWYRNGELLKECKQLTFLYDENDNCKLI 86

Query: 550 IPRAKASDAAWYQCTAQNVAGSTATRARL 578
           I   K +DA  Y+  A+N  G  +  A+L
Sbjct: 87  ITEGKHADAGEYKVVAENRHGKVSCSAKL 115



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 3/94 (3%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG-YVA 2036
            P F + +K+ ++ EG     E  +T   +P   VEWY NG  +++  +    YD      
Sbjct: 27   PVFKQKLKDCKIIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFLYDENDNCK 84

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            L I      D G Y   A N  G+   ++ + ++
Sbjct: 85   LIITEGKHADAGEYKVVAENRHGKVSCSAKLIIN 118



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 31/104 (29%), Positives = 46/104 (44%), Gaps = 9/104 (8%)

Query: 1571 DEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT--- 1627
            D+V    P+    LK+ +I EG  A FE ++    +   +VEWY N + LK   + T   
Sbjct: 20   DDVPKGPPVFKQKLKDCKIIEGSAARFECQI--TGNPEPEVEWYRNGELLKECKQLTFLY 77

Query: 1628 -ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
             E +N     L I      D+G Y   A N  G+   S   I++
Sbjct: 78   DENDN---CKLIITEGKHADAGEYKVVAENRHGKVSCSAKLIIN 118



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 33/139 (23%), Positives = 60/139 (43%), Gaps = 14/139 (10%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK-LTSDFGFVTLDLVDVYERD 2980
            +++EG     E Q+    +P+ ++EWY NG++L++  +   L  +     L + +    D
Sbjct: 37   KIIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFLYDENDNCKLIITEGKHAD 94

Query: 2981 SGIYTCKAYNKRGEAFTSSTVYCTSKDNLIERTQHPKGTEGLEKIQNLEDSLRKEPGQQP 3040
            +G Y   A N+ G+      V C++K  LI     P      E   + E  + +E  +  
Sbjct: 95   AGEYKVVAENRHGK------VSCSAK--LIINDPVPSDD---ESASDAESDISEEESEDE 143

Query: 3041 DDDTGRPPEFTTVFKDIVD 3059
            D D     +  T +  I D
Sbjct: 144  DKDVVLKSDAITKYYTIKD 162



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 3/90 (3%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFS-YVSL 2833
            VF   L +    EG    FEC +  + +P  ++EW+ N + L    +    +D +    L
Sbjct: 28   VFKQKLKDCKIIEGSAARFECQITGNPEP--EVEWYRNGELLKECKQLTFLYDENDNCKL 85

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             IT     D+G Y   A N  G  + S  L
Sbjct: 86   IITEGKHADAGEYKVVAENRHGKVSCSAKL 115



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 2508 PIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFG-FV 2566
            P+F Q L    ++ EG  A +E ++   G+P    EWY NG  LK   +    +D     
Sbjct: 27   PVFKQKLKD-CKIIEGSAARFECQIT--GNPEPEVEWYRNGELLKECKQLTFLYDENDNC 83

Query: 2567 TLDINSVVANDAGLYMCKAINRAG 2590
             L I      DAG Y   A NR G
Sbjct: 84   KLIITEGKHADAGEYKVVAENRHG 107


>SB_26454| Best HMM Match : I-set (HMM E-Value=7e-12)
          Length = 136

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 42/125 (33%), Positives = 68/125 (54%), Gaps = 4/125 (3%)

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE--RFSTLNVREG 505
           ++L + ++   DSG    VA+N  G+   Q  L V  KE++ AP+F E  R + L   E 
Sbjct: 2   YSLTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVV--KEKLFAPEFDEAQRSAPLVFEEE 59

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           + ++LN + +GTP P + W K+G  +  + +L I + G    L + +A A DA  Y+C A
Sbjct: 60  DEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEA 119

Query: 566 QNVAG 570
           +N  G
Sbjct: 120 KNKMG 124



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 42/135 (31%), Positives = 67/135 (49%), Gaps = 13/135 (9%)

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-KPQTKAANAPPEIIE 4627
            Y+L + +    DSG Y+ VA N+ G+ +  A  VV     K+K   P+   A     ++ 
Sbjct: 2    YSLTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVV-----KEKLFAPEFDEAQRSAPLVF 56

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
              +D+I+        + KI+G P P V WYK  + +  S   +++   D Y LR+ +A  
Sbjct: 57   EEEDEIM-------LNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAA 109

Query: 4688 EDEGDYKCVAYNSAG 4702
            +D G+YKC A N  G
Sbjct: 110  DDAGEYKCEAKNKMG 124



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 9/128 (7%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L +R +  +DS  +  VA+N  G  +  A LVV+EK       +  P F    ++  +  
Sbjct: 4    LTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVVKEK-------LFAPEFDEAQRSAPLVF 56

Query: 4528 GQL--VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
             +   + L+ K+ GT   +V W KNG+++    + +I      Y L + +A   D+G+Y+
Sbjct: 57   EEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYK 116

Query: 4586 CVAINSAG 4593
            C A N  G
Sbjct: 117  CEAKNKMG 124



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 34/119 (28%), Positives = 60/119 (50%), Gaps = 5/119 (4%)

Query: 240 ITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKL--QEGADAQFQVQLSGNPRPRV 297
           + +  VG+  VQ +  +   L     P+  +  R++ L  +E  +    +++ G P+P V
Sbjct: 20  VAQNTVGKCQVQAALVVKEKL---FAPEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEV 76

Query: 298 TWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
            W+KNG+RL +SN+ EI +  +   LRV      D+G Y   A+N  G  + +  + VE
Sbjct: 77  LWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 29/123 (23%), Positives = 49/123 (39%)

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
            Y+L + +   +D G YK VA N+ G+  V A L V +   A           +V  E   
Sbjct: 2    YSLTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVVKEKLFAPEFDEAQRSAPLVFEEEDE 61

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
                 +I    KP + W + G  + ++   ++   G+   L +     +D G + C A  
Sbjct: 62   IMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKN 121

Query: 4798 AAG 4800
              G
Sbjct: 122  KMG 124



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 3/127 (2%)

Query: 3105 MVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDG 3164
            M  L +   K  DSGTY   A N  G+ ++   L  V K K   P F    Q    L   
Sbjct: 1    MYSLTVRDLKRDDSGTYKLVAQNTVGKCQVQAAL--VVKEKLFAPEFD-EAQRSAPLVFE 57

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +       +  +  P  ++ WY NG+ +  S +++  S      L +      D+GEY C
Sbjct: 58   EEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKC 117

Query: 3225 RAYNKYG 3231
             A NK G
Sbjct: 118  EAKNKMG 124



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/93 (25%), Positives = 44/93 (47%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P+F +  ++A +       +   L  +  P   V WY NGR +   ++ + T       L
Sbjct: 43   PEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRL 102

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
             +  A A+D G Y C+A N +G ++ T  ++V+
Sbjct: 103  RVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 378 ETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDD 435
           + +  + + EK  AP+F +  +   +   E      + ++ G P PEV W+ N R++ D 
Sbjct: 29  QVQAALVVKEKLFAPEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDS 88

Query: 436 YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            N   + +    + L +      D+G   C A+NK G
Sbjct: 89  -NQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 24/64 (37%), Positives = 37/64 (57%), Gaps = 2/64 (3%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYV-SLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
           P   V WYK+GR +  S+++  I ++G V  L +    A+DAG Y   A NK+G ++ T 
Sbjct: 72  PKPEVLWYKNGRRLFDSNQL-EITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTF 130

Query: 859 SIRV 862
            I+V
Sbjct: 131 DIQV 134



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 20/64 (31%), Positives = 34/64 (53%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  ++ W+KNG  L    +L+ T    +  L +     DD+G Y C+A N +G ++ T  
Sbjct: 72   PKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTFD 131

Query: 2732 IKIE 2735
            I++E
Sbjct: 132  IQVE 135



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 17/66 (25%), Positives = 34/66 (51%)

Query: 2136 INDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVN 2195
            +  P   + W+ NG+++   ++   T       L +    A+D+G Y C+A NK+G ++ 
Sbjct: 69   LGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLR 128

Query: 2196 TCTLKV 2201
            T  ++V
Sbjct: 129  TFDIQV 134



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 1843 APRFI-TQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGF 1901
            AP F   Q + P    E        +I   P P   V WY NG+ L   ++   ++    
Sbjct: 42   APEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPE--VLWYKNGRRLFDSNQLEITSYGDV 99

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
              L +     +D+GEY C+A N +G ++ +  + V+
Sbjct: 100  YRLRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 21/93 (22%), Positives = 42/93 (45%)

Query: 1310 APQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
            AP+F  A  +   V      +   L+ +G     V W+ NG+ +   ++       D   
Sbjct: 42   APEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYR 101

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            L +     +D+G Y C+A N++G ++ +  ++V
Sbjct: 102  LRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQV 134



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 3968 DKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            +K   P F  + Q    LV  E  +    L  +G P  +V W+ NG+ L   N+   I  
Sbjct: 38   EKLFAPEF-DEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQL-EITS 95

Query: 4028 FGYV-AMNFGWVYPEDSGEYLCRATNLYGM 4056
            +G V  +       +D+GEY C A N  G+
Sbjct: 96   YGDVYRLRVFKAAADDAGEYKCEAKNKMGV 125



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 20/64 (31%), Positives = 29/64 (45%)

Query: 3722 VGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
            +G P   + W+ NGR     +++   +      L +    A DAGEY C A NK G +  
Sbjct: 69   LGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLR 128

Query: 3782 TAKI 3785
            T  I
Sbjct: 129  TFDI 132



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 4/72 (5%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQY 152
           K+ G P P V W +    L + N+  +      GDV  L + +    D GEY C A+N+ 
Sbjct: 67  KILGTPKPEVLWYKNGRRLFDSNQLEIT---SYGDVYRLRVFKAAADDAGEYKCEAKNKM 123

Query: 153 GEAICSVYIQPE 164
           G ++ +  IQ E
Sbjct: 124 GVSLRTFDIQVE 135



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            PK  + WY+NG+ L   ++           L +    A+D+GEY C A N  G
Sbjct: 72   PKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/94 (24%), Positives = 40/94 (42%)

Query: 1710 APVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            AP F    +   +   +       L  +G PK  V W +NG  +  SN+L          
Sbjct: 42   APEFDEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYR 101

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            L +     +D+G Y C A N++G ++ +  + V+
Sbjct: 102  LRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            P  +V WY NG+ L   ++      +G V  L +     +D+GEY C A N  G ++ T 
Sbjct: 72   PKPEVLWYKNGRRLFDSNQLE-ITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTF 130

Query: 3509 SMKVQ 3513
             ++V+
Sbjct: 131  DIQVE 135



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F +   + P V E ++  +   L+ +G P   V W+ NGR +   ++ +         
Sbjct: 43   PEFDEAQRSAPLVFEEED-EIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYR 101

Query: 1237 LDIIHATSADTGEYTVRAVNHLG 1259
            L +  A + D GEY   A N +G
Sbjct: 102  LRVFKAAADDAGEYKCEAKNKMG 124



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 4123 EEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT-YDGMYHFDIPKTRQYDTGK 4179
            EE +      ++ G PKP V+W  NG  + + ++ ++T Y  +Y   + K    D G+
Sbjct: 57   EEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGE 114



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 1/91 (1%)

Query: 2234 VEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI 2293
            V + K+  P F    R    VFE +       ++ +  P   + +Y NG+ L  + +  I
Sbjct: 35   VVKEKLFAPEFDEAQRSAPLVFEEED-EIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEI 93

Query: 2294 TFDFGYVSLDIQHCVPEDAGEYSVKAINALG 2324
            T       L +     +DAGEY  +A N +G
Sbjct: 94   TSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 17/53 (32%), Positives = 27/53 (50%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            P  ++ WY NG+ L   ++ ++TS      L +      D+G Y C+A NK G
Sbjct: 72   PKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 12/37 (32%), Positives = 25/37 (67%)

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
            +L +  ++ +DSG Y +VA+N  G+ Q+ A++ V+ +
Sbjct: 3    SLTVRDLKRDDSGTYKLVAQNTVGKCQVQAALVVKEK 39



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+F  + Q    LV  +       L  +  P  +V W+ NG++L   ++        +  
Sbjct: 43   PEF-DEAQRSAPLVFEEEDEIMLNLKILGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYR 101

Query: 3342 LDILYCYEENSGEYECVATNKLG 3364
            L +     +++GEY+C A NK+G
Sbjct: 102  LRVFKAAADDAGEYKCEAKNKMG 124



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 15/56 (26%), Positives = 28/56 (50%)

Query: 2403 VGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            +G P  +V W++N + + DS+++  T       + +     +D G Y C A N +G
Sbjct: 69   LGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 18/56 (32%), Positives = 25/56 (44%)

Query: 2535 VGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            +G P     WY NG  L   ++   T       L +    A+DAG Y C+A N+ G
Sbjct: 69   LGTPKPEVLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMG 124



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-SLDMLSLNIQDSGEYTCRAVSATGVA 720
           +G P  ++ W KNG+ +  S++   I  +G +  L +      D+GEY C A +  GV+
Sbjct: 69  LGTPKPEVLWYKNGRRLFDSNQL-EITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVS 126



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 16/60 (26%), Positives = 30/60 (50%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            V WY NG+++  +N+++         L +    A+D+G Y   A+N  G +  +  + VE
Sbjct: 76   VLWYKNGRRLFDSNQLEITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQVE 135



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 2/61 (3%)

Query: 3591 VEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            V W+ NG+ L   ++++ I  +G V  L +      DAG Y C+A N+ G +  +  +QV
Sbjct: 76   VLWYKNGRRLFDSNQLE-ITSYGDVYRLRVFKAAADDAGEYKCEAKNKMGVSLRTFDIQV 134

Query: 3650 K 3650
            +
Sbjct: 135  E 135


>SB_12405| Best HMM Match : I-set (HMM E-Value=8.8e-21)
          Length = 198

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 13/165 (7%)

Query: 4539 GTKPIDVYWLKNGKKVQPDIRNKILEED-GTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
            GT    V + +  +++    R  I+EE+ G + L I    P+D+G+Y+C+A+N AGE   
Sbjct: 13   GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTS 72

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
                   L   ++   PQ       P ++E      + +G   + S ++ G P P ++WY
Sbjct: 73   KGY----LHVEEELTIPQF--IGDVPGVVE------LVQGDNYDLSLEVRGTPRPEIEWY 120

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
              ++LI  +   Q+S  + + T+ +     +D G Y+C A N+AG
Sbjct: 121  HNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165



 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 3/156 (1%)

Query: 417 GRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAF 476
           G P P VT+     QI D   + I+  E+G   L I N    D+G   C+A N +GE   
Sbjct: 13  GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTS 72

Query: 477 QCRLNVIEKEQVVAPKFV-ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP 535
           +  L+V  +E++  P+F+ +    + + +G+   L+    GTP P I W  +   I    
Sbjct: 73  KGYLHV--EEELTIPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATS 130

Query: 536 ELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            +++      +T+ +      D+  Y+C A N AG+
Sbjct: 131 RVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGT 166



 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 10/158 (6%)

Query: 4648 GKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
            G P+P V +++  +++    +Y  +      + L I    PED G+Y+C+A N AG VT 
Sbjct: 13   GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTS 72

Query: 4707 AAKLKV----TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP 4762
               L V    T P    ++P +  L      +G       ++    +P I+W     LI 
Sbjct: 73   KGYLHVEEELTIPQFIGDVPGVVEL-----VQGDNYDLSLEVRGTPRPEIEWYHNERLIY 127

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             T   Q+    + A + + N   +D+G + C+A   AG
Sbjct: 128  ATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 2/98 (2%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+FI  + G  +L +G +  Y+  +E    P   +EWY N +++ +  R + S     A 
Sbjct: 85   PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            + +  V  +DSG Y CKA+N  G       +NVQ   S
Sbjct: 143  IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGSS 180



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 33/194 (17%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHT-TLRVRNTQKSDSGHYTLLAENPNGCIVT 349
           G P P VT+ +  +++ +  ++ I+   N    L +RNT+  D+G Y         CI  
Sbjct: 13  GTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQ--------CIAV 64

Query: 350 SGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV-KVCQDRDVTEGKM 408
           +G  A E  ++ Y                    + + E+   PQF+  V    ++ +G  
Sbjct: 65  NG--AGEVTSKGY--------------------LHVEEELTIPQFIGDVPGVVELVQGDN 102

Query: 409 TRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVAR 468
                 V G P PE+ W+ N+R I      ++    S    + + NVTL DSG+  C A 
Sbjct: 103 YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISS-KATIALYNVTLDDSGLYRCKAV 161

Query: 469 NKSGETAFQCRLNV 482
           N +G  + Q  +NV
Sbjct: 162 NTAGTGSKQFNINV 175



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 36/137 (26%), Positives = 62/137 (45%), Gaps = 4/137 (2%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G+ VL I  T+  D+G Y C A N  G  E++ K     + +   P+F   +  +  L  
Sbjct: 42   GLFVLTIRNTRPEDAGEYQCIAVN--GAGEVTSKGYLHVEEELTIPQFIGDVPGVVELVQ 99

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G   +++ ++     P  +IEWYHN + +  ++R++         + +      DSG Y 
Sbjct: 100  GD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYR 157

Query: 3224 CRAYNKYGEDFTRATIN 3240
            C+A N  G    +  IN
Sbjct: 158  CKAVNTAGTGSKQFNIN 174



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 7/160 (4%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQI-HTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAK 4493
            +G P+P + ++RE+  I +   + I    +   +L IR    ED+  +  +A N  G   
Sbjct: 12   EGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVT 71

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
                L VEE+        +P         V +  G    L  +V GT   ++ W  N + 
Sbjct: 72   SKGYLHVEEELT------IPQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERL 125

Query: 4554 VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAG 4593
            +    R ++       T+ +      DSG Y C A+N+AG
Sbjct: 126  IYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 5/117 (4%)

Query: 1024 EDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNG 1083
            E  S+     EEE+ I   P+F+G + G  ++V+G +  ++  +E +      +EWY N 
Sbjct: 69   EVTSKGYLHVEEELTI---PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNE 123

Query: 1084 KQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSS 1140
            + I + +R+Q         + + +V  +DSG+Y   A N AG      ++ V+  SS
Sbjct: 124  RLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGSS 180



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 27/94 (28%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P F   +    +LV+G +  L  +V  R  P  +IEW+ N   +   +R++ +F     T
Sbjct: 85   PQFIGDVPGVVELVQGDNYDLSLEV--RGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            +++ ++  DDSG+Y CKA N  G      +I ++
Sbjct: 143  IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQ 176



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 3/106 (2%)

Query: 762 IEEQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITS 821
           +EE+ +  PQFI  +  + EL +G N  ++  L     P   +EWY + R I A+SR+  
Sbjct: 78  VEEELTI-PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQL 134

Query: 822 IFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAARST 867
            F     ++ + ++  +D+G Y  +AVN  G      +I V   S+
Sbjct: 135 SFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGSS 180



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 1/96 (1%)

Query: 3828 TPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFV 3887
            T P+FI  +    VE  +G  ++  +E +  P+  IEWY N +L+ +  R +  +     
Sbjct: 83   TIPQFIGDVPG-VVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKA 141

Query: 3888 SLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKK 3923
            ++ +  V  +DSG Y C+AVN  G    +  I+ ++
Sbjct: 142  TIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQR 177



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 1/92 (1%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           PQFI  +  V  +  G  +++  +E  G P  +IEW  N + I A+SR    F     ++
Sbjct: 85  PQFIGDVPGVVELVQGD-NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATI 143

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
            + ++ + DSG Y C+AV+  G    +  ++V
Sbjct: 144 ALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV 175



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 2/89 (2%)

Query: 2905 DTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS 2964
            + E   P++I  +    +LV+G    L   +E +  P  +IEWY N +++   SR +L+ 
Sbjct: 79   EEELTIPQFIGDVPGVVELVQGDNYDLS--LEVRGTPRPEIEWYHNERLIYATSRVQLSF 136

Query: 2965 DFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
                 T+ L +V   DSG+Y CKA N  G
Sbjct: 137  ISSKATIALYNVTLDDSGLYRCKAVNTAG 165



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 24/103 (23%), Positives = 55/103 (53%), Gaps = 3/103 (2%)

Query: 2232 IEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARF 2291
            + VEE +++ P+F+ ++ G   + +G   +++  +E    P   IE+YHN + + + +R 
Sbjct: 76   LHVEE-ELTIPQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRV 132

Query: 2292 HITFDFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
             ++F     ++ + +   +D+G Y  KA+N  G  +   ++ V
Sbjct: 133  QLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV 175



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 2/100 (2%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTF 961
            V E    P+F   +   + + +G   +++  LE  G     +EW  + R + A+SR+   
Sbjct: 78   VEEELTIPQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLS 135

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            F      + + +VT+ D+G Y C+A N  G  +   N+ +
Sbjct: 136  FISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV 175



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 2/89 (2%)

Query: 2502 DREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTH 2561
            + E   P F   + G  EL +G +  Y+  +   G P    EWY N   +   SR + + 
Sbjct: 79   EEELTIPQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSF 136

Query: 2562 DFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                 T+ + +V  +D+GLY CKA+N AG
Sbjct: 137  ISSKATIALYNVTLDDSGLYRCKAVNTAG 165



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+F      +V++ +G   +Y+ SL   G     IEW++N + I A+ R++  +      
Sbjct: 85   PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142

Query: 3108 LEILGTKTTDSGTYSCRATNKWG 3130
            + +      DSG Y C+A N  G
Sbjct: 143  IALYNVTLDDSGLYRCKAVNTAG 165



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P F   +  +  + +G   ++D  L   G P  ++EW+ NE+LI  +SR+  +      +
Sbjct: 85   PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + + +V  +D G+Y C+A N  G
Sbjct: 143  IALYNVTLDDSGLYRCKAVNTAG 165



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G P P V++ R+   + +  +YS+   E+ G   L I+   P D GEY C A N  GE  
Sbjct: 13  GTPVPAVTFHRESEQIYDGGRYSI-VEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVT 71

Query: 157 CSVYIQPE 164
              Y+  E
Sbjct: 72  SKGYLHVE 79



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 3679 LHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPF 3738
            LH  EE+TI       P+F  ++   +++ +G   ++D  +E  G P   I+W+HN R  
Sbjct: 76   LHVEEELTI-------PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLI 126

Query: 3739 ATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSAT 3780
               SRV          + +  +   D+G Y C+A N  G+ +
Sbjct: 127  YATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGTGS 168



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 3/104 (2%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F+  +     + +G N  L   LE  G P   +EW+HN R +   SR +  +      
Sbjct: 85   PQFIGDVPGVVELVQGDNYDLS--LEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQ 1280
            + + + T  D+G Y  +AVN  G+      + V +R     D Q
Sbjct: 143  IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINV-QRGSSRVDLQ 185



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/84 (27%), Positives = 47/84 (55%), Gaps = 3/84 (3%)

Query: 2776 FISHLNNIV-CKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            FI  +  +V   +GDN  ++ ++E    P  +IEW+ N + + + +R + +   S  ++ 
Sbjct: 87   FIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIA 144

Query: 2835 ITHTYEEDSGIYTCKATNSKGSAT 2858
            + +   +DSG+Y CKA N+ G+ +
Sbjct: 145  LYNVTLDDSGLYRCKAVNTAGTGS 168



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 3/92 (3%)

Query: 1436 IDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRP 1495
            ++E +TI P+F+     +  +++G +  ++  LE       ++EW+ N + +    R + 
Sbjct: 78   VEEELTI-PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQL 134

Query: 1496 IHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527
                    + + ++  +DSG+Y C+AVN  GT
Sbjct: 135  SFISSKATIALYNVTLDDSGLYRCKAVNTAGT 166



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F+  +  +  L +GD  +++  +E    P   I+W+HN + I A  R + +       
Sbjct: 85   PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142

Query: 2169 LDILYTYAEDSGTYMCKATNKLG 2191
            + +     +DSG Y CKA N  G
Sbjct: 143  IALYNVTLDDSGLYRCKAVNTAG 165



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 6/93 (6%)

Query: 1301 VREDITVMQAPQFSRALHNI-ETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRF 1359
            V E++T+   PQF   +  + E V+G N  L   ++  G     +EW+ N + I    R 
Sbjct: 78   VEEELTI---PQFIGDVPGVVELVQGDNYDLSLEVR--GTPRPEIEWYHNERLIYATSRV 132

Query: 1360 RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG 1392
            + ++      + L +V  +DSG+Y C+A N  G
Sbjct: 133  QLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 20/81 (24%), Positives = 38/81 (46%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P  I   P   +L +G +    +++ G PRP + W+ N + +  +++ ++    +  T+ 
Sbjct: 85  PQFIGDVPGVVELVQGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIA 144

Query: 325 VRNTQKSDSGHYTLLAENPNG 345
           + N    DSG Y   A N  G
Sbjct: 145 LYNVTLDDSGLYRCKAVNTAG 165



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 1602 IPVSDATLKVEWYHNNKPLKSGSRFT--ETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            +P       V ++  ++ +  G R++  E  N G   L I +  PED+G Y C A+N  G
Sbjct: 10   VPEGTPVPAVTFHRESEQIYDGGRYSIVEEEN-GLFVLTIRNTRPEDAGEYQCIAVNGAG 68

Query: 1660 EAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTSKY 1697
            E  + G   V  + +I    Q  G +P + +L     Y
Sbjct: 69   EVTSKGYLHVEEELTI---PQFIGDVPGVVELVQGDNY 103



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 3/110 (2%)

Query: 3414 EEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFC 3473
            EE+   P F   +  +  L +G+N  ++  L     P  ++EWY N + + A SR +   
Sbjct: 79   EEELTIPQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSF 136

Query: 3474 DFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ-GKRNIILES 3522
                  + +     +DSG Y C+A N  G      ++ VQ G   + L++
Sbjct: 137  ISSKATIALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGSSRVDLQA 186



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 1735 IPVGDPKLRVEWLRNGVPIEASNRLTTMHDF-GYVALNMKYVNPEDSGTYTCRAINELGE 1793
            +P G P   V + R    I    R + + +  G   L ++   PED+G Y C A+N  GE
Sbjct: 10   VPEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGE 69

Query: 1794 AVTSSTLFVQSKASL 1808
              +   L V+ + ++
Sbjct: 70   VTSKGYLHVEEELTI 84



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 22/82 (26%), Positives = 37/82 (45%)

Query: 1726 QAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTC 1785
            Q  +++  L   G P+  +EW  N   I A++R+          + +  V  +DSG Y C
Sbjct: 99   QGDNYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRC 158

Query: 1786 RAINELGEAVTSSTLFVQSKAS 1807
            +A+N  G       + VQ  +S
Sbjct: 159  KAVNTAGTGSKQFNINVQRGSS 180



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 20/70 (28%), Positives = 34/70 (48%)

Query: 4432 VEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGT 4491
            +E  G P P I+WY     I  +   Q+   S+K+ + +  V ++DS ++   A N  GT
Sbjct: 107  LEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAGT 166

Query: 4492 AKCSANLVVE 4501
                 N+ V+
Sbjct: 167  GSKQFNINVQ 176



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 662 PVGDPTMKIEWLKNGQSIEASSRFTSIFRF-GYISLDMLSLNIQDSGEYTCRAVSATGVA 720
           P G P   + + +  + I    R++ +    G   L + +   +D+GEY C AV+  G  
Sbjct: 11  PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70

Query: 721 ETKAVLHVTPRATI 734
            +K  LHV    TI
Sbjct: 71  TSKGYLHVEEELTI 84



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 3566 DLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQR 3625
            +L+  +N     E R  P  +    +EW+HN + +   SRV+         + +  V   
Sbjct: 96   ELVQGDNYDLSLEVRGTPRPE----IEWYHNERLIYATSRVQLSFISSKATIALYNVTLD 151

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVK 3650
            D+GLY CKA N  G  +    + V+
Sbjct: 152  DSGLYRCKAVNTAGTGSKQFNINVQ 176



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 15/50 (30%), Positives = 27/50 (54%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            ++EWYHN + + + SR   +       + + +   +DSG Y C+A+N  G
Sbjct: 116  EIEWYHNERLIYATSRVQLSFISSKATIALYNVTLDDSGLYRCKAVNTAG 165



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 1870 PYPDPNMRVEWYFNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            P   P   V ++   + +  G RY     + G   L I     ED+GEY C A+N  G+ 
Sbjct: 11   PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70

Query: 1929 VSSIRLNVQSKESI 1942
             S   L+V+ + +I
Sbjct: 71   TSKGYLHVEEELTI 84



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 3446 PTDDPNLKVEWYWNGKSLKAGSRFRTFCDF-GFVILEISPTYPEDSGEYLCRAYNNYGEA 3504
            P   P   V ++   + +  G R+    +  G  +L I  T PED+GEY C A N  GE 
Sbjct: 11   PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70

Query: 3505 VTTASMKVQGKRNI 3518
             +   + V+ +  I
Sbjct: 71   TSKGYLHVEEELTI 84



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNA-VLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P + + RE   I +   + ++ E N   VL I NT  ED G + C A   AG+V +   L
Sbjct: 17   PAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYL 76

Query: 4809 VVKSK 4813
             V+ +
Sbjct: 77   HVEEE 81



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 3/97 (3%)

Query: 1978 PQFGKPIKNA-EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA 2036
            PQF   +    E+ +G   + + +L     P   +EWY N R +    R + ++      
Sbjct: 85   PQFIGDVPGVVELVQGD--NYDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKS 2073
            + +     +D+G Y CKA N  G      ++ V   S
Sbjct: 143  IALYNVTLDDSGLYRCKAVNTAGTGSKQFNINVQRGS 179



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 2/91 (2%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVI 3341
            P+FI  +  V +LV+G +  ++  L     P  ++EW++N + +    R +         
Sbjct: 85   PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142

Query: 3342 LDILYCYEENSGEYECVATNKLGRDSTKANL 3372
            + +     ++SG Y C A N  G  S + N+
Sbjct: 143  IALYNVTLDDSGLYRCKAVNTAGTGSKQFNI 173



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%)

Query: 2401 IPVGDPTLKVEWFRNEKLIEDSSRITKTHDF-GYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            +P G P   V + R  + I D  R +   +  G   +TI + R ED G Y C A N  GE
Sbjct: 10   VPEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGE 69



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 1/63 (1%)

Query: 3855 PKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-GFVSLDILYVYAEDSGEYICRAVNDFGED 3913
            P+  P   + ++R  + +  G RY  V +  G   L I     ED+GEY C AVN  GE 
Sbjct: 11   PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70

Query: 3914 FTK 3916
             +K
Sbjct: 71   TSK 73



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 2268 PVHDPNLRIEFYHNGKALQSAARFHITFDF-GYVSLDIQHCVPEDAGEYSVKAINALGHC 2326
            P   P   + F+   + +    R+ I  +  G   L I++  PEDAGEY   A+N  G  
Sbjct: 11   PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70

Query: 2327 TS 2328
            TS
Sbjct: 71   TS 72



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 1/79 (1%)

Query: 796 PVSDPTMRVEWYKDGRPITASSRITSIFNF-GYVSLNIMHLRAEDAGSYTVRAVNKLGEA 854
           P   P   V ++++   I    R + +    G   L I + R EDAG Y   AVN  GE 
Sbjct: 11  PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70

Query: 855 ISTASIRVAARSTVTADLG 873
            S   + V    T+   +G
Sbjct: 71  TSKGYLHVEEELTIPQFIG 89



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 1/67 (1%)

Query: 3307 VPVDDPDLKVEWFYNGKKLPHGHRYRTFHDF-GIVILDILYCYEENSGEYECVATNKLGR 3365
            VP   P   V +    +++  G RY    +  G+ +L I     E++GEY+C+A N  G 
Sbjct: 10   VPEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGE 69

Query: 3366 DSTKANL 3372
             ++K  L
Sbjct: 70   VTSKGYL 76



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P+F+  +     LV+ +   ++  L   G P  ++EW+ N + +   +R    +      
Sbjct: 85   PQFIGDVPGVVELVQGDN--YDLSLEVRGTPRPEIEWYHNERLIYATSRVQLSFISSKAT 142

Query: 4033 MNFGWVYPEDSGEYLCRATNLYG 4055
            +    V  +DSG Y C+A N  G
Sbjct: 143  IALYNVTLDDSGLYRCKAVNTAG 165



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            GL  L+I + R +D+G Y C A N  GE  S   + +E+
Sbjct: 42   GLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEE 80



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 1/74 (1%)

Query: 1069 PQSDLTMTVEWYFNGKQITSANRIQTYHDF-GYVALDIASVRAEDSGVYTVVARNAAGEA 1127
            P+      V ++   +QI    R     +  G   L I + R ED+G Y  +A N AGE 
Sbjct: 11   PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70

Query: 1128 QLSASMTVETRSSI 1141
                 + VE   +I
Sbjct: 71   TSKGYLHVEEELTI 84



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 1/68 (1%)

Query: 2135 PINDPHLTIDWFHNGQKIRAGHRYRTTHDF-GYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            P   P   + +    ++I  G RY    +  G   L I  T  ED+G Y C A N  GE 
Sbjct: 11   PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70

Query: 2194 VNTCTLKV 2201
             +   L V
Sbjct: 71   TSKGYLHV 78



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 2799 PSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LDITHTYEEDSGIYTCKATNSKGSA 2857
            P   P   + +   ++ +  G RY    + + +  L I +T  ED+G Y C A N  G  
Sbjct: 11   PEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLTIRNTRPEDAGEYQCIAVNGAGEV 70

Query: 2858 TTSGSL 2863
            T+ G L
Sbjct: 71   TSKGYL 76



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 14/37 (37%), Positives = 19/37 (51%)

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            G   LTI++    DAG Y C A N  G+ T+   L +
Sbjct: 42   GLFVLTIRNTRPEDAGEYQCIAVNGAGEVTSKGYLHV 78


>SB_11883| Best HMM Match : I-set (HMM E-Value=0)
          Length = 616

 Score = 69.7 bits (163), Expect = 5e-11
 Identities = 78/289 (26%), Positives = 115/289 (39%), Gaps = 33/289 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G PLP+I W R    I N+     +         I    V+D+ ++  VA N  G    S
Sbjct: 347  GFPLPVISWRRGGQAINNTQSALRYR--------IENARVKDTGIYTCVARNLVGYDYSS 398

Query: 4496 ANLVVEEKR----RQGRGGIV----PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW 4547
            +N+ +   +    R     +         T   +NV   SG  V L    TG     + W
Sbjct: 399  SNISIVAAKPPIIRTSTHHLTVLRRDKISTDLGKNVTTLSGNTVSLLCNATGVPSPKLSW 458

Query: 4548 LKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVV---S 4604
             K+G+ +  ++ + +L      TL  L   P DSG Y C A N  G    D+   V   S
Sbjct: 459  YKDGETL--NVSHAVL------TLPTLS--PSDSGLYRCEARNLKGVDDADSYLTVLVGS 508

Query: 4605 LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
             P+ +   +  T+  N    +     D I      +E +C + G PLP++ W K  + +K
Sbjct: 509  PPSIRTTSENITETENIAYIVTGIGSDVITLLSSNVEVTCPVRGFPLPSITWLKDGQPLK 568

Query: 4665 PSKYFQMSR-TADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
             S   +++  T   Y L I E      G Y CVA NS G  T    L V
Sbjct: 569  QSMTVKVNNLTGTLYLLSILE---RRAGLYMCVATNSLGAATATTTLNV 614



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 73/296 (24%), Positives = 112/296 (37%), Gaps = 51/296 (17%)

Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
           +  G P P +TW KNG  L    +   +    H  L +  +   DSG Y   A N  G  
Sbjct: 237 ETEGLPAPNITWKKNGVALPVDGR---MYARGHI-LFIAESLTRDSGVYICEATNIAGSK 292

Query: 348 VTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407
                L V +P E          IT T QR  EE   +S       +++  +  ++T   
Sbjct: 293 QAKSELKVIAPVEPV--------ITATVQR-LEELRPVSITTEVGSYIRTLETSNLT--- 340

Query: 408 MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVA 467
                C V G P P ++W    + I          N        I N  + D+G+ TCVA
Sbjct: 341 ---LVCTVRGFPLPVISWRRGGQAIN---------NTQSALRYRIENARVKDTGIYTCVA 388

Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL-----------NVR--EGEPVVLNARA 514
           RN  G       ++++  +  +        + L           NV    G  V L   A
Sbjct: 389 RNLVGYDYSSSNISIVAAKPPIIRTSTHHLTVLRRDKISTDLGKNVTTLSGNTVSLLCNA 448

Query: 515 VGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            G P+P+++W KDG  +          +   + L +P    SD+  Y+C A+N+ G
Sbjct: 449 TGVPSPKLSWYKDGETL----------NVSHAVLTLPTLSPSDSGLYRCEARNLKG 494



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 75/313 (23%), Positives = 116/313 (37%), Gaps = 39/313 (12%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P   +  Q     +  +  +  +  G    ++ W KNG  +  D R   +   G + L I
Sbjct: 215  PLGLVIGQTARTLTRIIFNITCETEGLPAPNITWKKNGVALPVDGR---MYARG-HILFI 270

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATK-DKPKPQTKAANAPPEIIEPLKDK 4632
             E+  +DSG Y C A N AG  +  +E  V  P         Q      P  I   +   
Sbjct: 271  AESLTRDSGVYICEATNIAGSKQAKSELKVIAPVEPVITATVQRLEELRPVSITTEVGSY 330

Query: 4633 I-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            I   E   +   C + G PLP + W +G + I        + T      RI  A  +D G
Sbjct: 331  IRTLETSNLTLVCTVRGFPLPVISWRRGGQAI--------NNTQSALRYRIENARVKDTG 382

Query: 4692 DYKCVA-------YNSAGRVTVAAKLKVTQPDQADNLPAL------TPL-RDIVVYEGQP 4737
             Y CVA       Y+S+    VAAK  + +     +L  L      T L +++    G  
Sbjct: 383  IYTCVARNLVGYDYSSSNISIVAAKPPIIR-TSTHHLTVLRRDKISTDLGKNVTTLSGNT 441

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
                   T    P + W ++G    ET +       ++AVL +      D+G + C A  
Sbjct: 442  VSLLCNATGVPSPKLSWYKDG----ETLNV------SHAVLTLPTLSPSDSGLYRCEARN 491

Query: 4798 AAGQVETSAKLVV 4810
              G  +  + L V
Sbjct: 492  LKGVDDADSYLTV 504



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 112/468 (23%), Positives = 166/468 (35%), Gaps = 97/468 (20%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W +NGV +    R+       ++A ++      DSG Y C A N  G     
Sbjct: 240  GLPAPNITWKKNGVALPVDGRMYARGHILFIAESLT----RDSGVYICEATNIAGSKQAK 295

Query: 1798 STLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLS 1857
            S L    K    +E    + +Q++++L   S                   T++    +  
Sbjct: 296  SEL----KVIAPVEPVITATVQRLEELRPVS-----------------ITTEVGSYIRTL 334

Query: 1858 EGQSAHYECRIEPYPDPNMRVEWYFNGKVL---QSGHRYRTSNDFGFAALDILTVYGEDS 1914
            E  +    C +  +P P   + W   G+ +   QS  RYR  N              +D+
Sbjct: 335  ETSNLTLVCTVRGFPLPV--ISWRRGGQAINNTQSALRYRIEN-----------ARVKDT 381

Query: 1915 GEYTCKAINNLGQAVSSIRLN-VQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSF 1973
            G YTC A N +G   SS  ++ V +K  IIR S H   + +   +  D            
Sbjct: 382  GIYTCVARNLVGYDYSSSNISIVAAKPPIIRTSTHHLTVLRRDKISTD------------ 429

Query: 1974 VVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFG 2033
                   GK   N     G+ V L    T V  P+ ++ WY +G  +   H         
Sbjct: 430  ------LGK---NVTTLSGNTVSLLCNATGV--PSPKLSWYKDGETLNVSH--------- 469

Query: 2034 YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEK 2093
               L +      D+G Y C+A N  G     S + V   S   + T  E     I E E 
Sbjct: 470  -AVLTLPTLSPSDSGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTTSEN----ITETEN 524

Query: 2094 YERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIR 2153
                  I     G     +T L+S             C V     P +T  W  +GQ ++
Sbjct: 525  ------IAYIVTGIGSDVITLLSS--------NVEVTCPVRGFPLPSIT--WLKDGQPLK 568

Query: 2154 AGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                 +  +  G   L +L      +G YMC ATN LG A  T TL V
Sbjct: 569  QSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATATTTLNV 614



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 110/465 (23%), Positives = 177/465 (38%), Gaps = 94/465 (20%)

Query: 1202 EPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSA 1261
            E  G P   + W  NG ++ V  R    Y  G + L I  + + D+G Y   A N  GS 
Sbjct: 237  ETEGLPAPNITWKKNGVALPVDGRM---YARGHI-LFIAESLTRDSGVYICEATNIAGSK 292

Query: 1262 HTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSRALHNIE 1321
               + ++VI   + V  T   Q +E+++ +         +R                   
Sbjct: 293  QAKSELKVIAPVEPVI-TATVQRLEELRPVSITTEVGSYIR------------------- 332

Query: 1322 TVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIK-TGHRFRPAYEFDYVALDLLSVYPEDS 1380
            T+E +N+ L C ++  G     + W   G+ I  T    R  Y  +   +       +D+
Sbjct: 333  TLETSNLTLVCTVR--GFPLPVISWRRGGQAINNTQSALR--YRIENARV-------KDT 381

Query: 1381 GVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESV 1440
            G+YTC A N +G   +S  + ++A K  I+ +          +L    R K +  + ++V
Sbjct: 382  GIYTCVARNLVGYDYSSSNISIVAAKPPIIRTS-------THHLTVLRRDKISTDLGKNV 434

Query: 1441 TIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFG 1500
            T               + G  V   C    V     K+ W+K+G+ + + H         
Sbjct: 435  T--------------TLSGNTVSLLCNATGVPSP--KLSWYKDGETLNVSH--------- 469

Query: 1501 YVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCR-STTDIVRSTQNEAGLEQIQVLE 1559
               L +  L   DSG+Y C A NL G D+    LT    +   +R+T      E I   E
Sbjct: 470  -AVLTLPTLSPSDSGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTTS-----ENITETE 523

Query: 1560 DRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKP 1619
            + + Y  T +  +V T          NVE+    R        P+   T    W  + +P
Sbjct: 524  NIA-YIVTGIGSDVITLLS------SNVEVTCPVRG------FPLPSIT----WLKDGQP 566

Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTS 1664
            LK        N  G   L ++S L   +G Y C A N+LG A  +
Sbjct: 567  LKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATAT 609



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 71/304 (23%), Positives = 121/304 (39%), Gaps = 61/304 (20%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
           G P P ++W + GQ + N        T +    R+ N +  D+G YT +A N  G   +S
Sbjct: 347 GFPLPVISWRRGGQAINN--------TQSALRYRIENARVKDTGIYTCVARNLVGYDYSS 398

Query: 351 GYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410
             +++ +     ++       T T       R +IS          + ++     G    
Sbjct: 399 SNISIVAAKPPIIR-------TSTHHLTVLRRDKIS--------TDLGKNVTTLSGNTVS 443

Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470
             C  TG P P+++W+ +   +  + +H +L          +  ++ SDSG+  C ARN 
Sbjct: 444 LLCNATGVPSPKLSWYKDGETL--NVSHAVLT---------LPTLSPSDSGLYRCEARNL 492

Query: 471 SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT------------- 517
            G       L V+    V +P  + R ++ N+ E E +      +G+             
Sbjct: 493 KGVDDADSYLTVL----VGSPPSI-RTTSENITETENIAYIVTGIGSDVITLLSSNVEVT 547

Query: 518 ------PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG- 570
                 P P ITW KDG P+  +  ++++   G  TL +       A  Y C A N  G 
Sbjct: 548 CPVRGFPLPSITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGA 605

Query: 571 STAT 574
           +TAT
Sbjct: 606 ATAT 609



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 49/211 (23%), Positives = 79/211 (37%), Gaps = 27/211 (12%)

Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
           +N     G         +G P P+++W+K+G+ L  S          H  L +     SD
Sbjct: 432 KNVTTLSGNTVSLLCNATGVPSPKLSWYKDGETLNVS----------HAVLTLPTLSPSD 481

Query: 333 SGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAP 392
           SG Y   A N  G      YL V   +   ++   S+ IT+T      E I      +  
Sbjct: 482 SGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTT-SENITET------ENIAYIVTGIGS 534

Query: 393 QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMI 452
             + +               C V G P P +TW  + + ++     K+  N +G   L +
Sbjct: 535 DVITLLSSN-------VEVTCPVRGFPLPSITWLKDGQPLKQSMTVKVN-NLTGT--LYL 584

Query: 453 TNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            ++    +G+  CVA N  G       LNV+
Sbjct: 585 LSILERRAGLYMCVATNSLGAATATTTLNVL 615



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 4/80 (5%)

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            E   +  +CK  G PLPTV+W KG + +  SK  ++        L + +A   D G+Y+C
Sbjct: 20   EKAPVTLTCKATGLPLPTVRWIKGGRQL-VSKGHEIVAGG---RLFLGKATLGDSGEYEC 75

Query: 4696 VAYNSAGRVTVAAKLKVTQP 4715
             A +  G V+  + L++  P
Sbjct: 76   TATSPLGYVSAKSNLEIKVP 95



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 8/132 (6%)

Query: 3521 ESQLPKGMEGTIDKIAALEGYSGTVDTLTPE-AESGNPPEFTT-TPSDLILSENSSAHFE 3578
            E++  KG++     +  L G   ++ T +    E+ N     T   SD+I   +S+    
Sbjct: 488  EARNLKGVDDADSYLTVLVGSPPSIRTTSENITETENIAYIVTGIGSDVITLLSSNVEVT 547

Query: 3579 CRLIPVNDSSM-RVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNR 3637
            C   PV    +  + W  +G+PL     VK  N  G + L    + +R AGLY C ATN 
Sbjct: 548  C---PVRGFPLPSITWLKDGQPLKQSMTVKVNNLTGTLYLL--SILERRAGLYMCVATNS 602

Query: 3638 HGEATVSCKLQV 3649
             G AT +  L V
Sbjct: 603  LGAATATTTLNV 614



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 44/171 (25%), Positives = 60/171 (35%), Gaps = 26/171 (15%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C   G P P +TW  N   +  D         +  H L I      DSGV  C A N +G
Sbjct: 236 CETEGLPAPNITWKKNGVALPVDGRMY-----ARGHILFIAESLTRDSGVYICEATNIAG 290

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERF-------------STLNVREGEPVVLNARAVGTPT 519
               +  L VI   + V    V+R              S +   E   + L     G P 
Sbjct: 291 SKQAKSELKVIAPVEPVITATVQRLEELRPVSITTEVGSYIRTLETSNLTLVCTVRGFPL 350

Query: 520 PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           P I+W++ G          I+    A    I  A+  D   Y C A+N+ G
Sbjct: 351 PVISWRRGG--------QAINNTQSALRYRIENARVKDTGIYTCVARNLVG 393



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 101/476 (21%), Positives = 176/476 (36%), Gaps = 93/476 (19%)

Query: 929  FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
            F    E  G     + W K+G  +    R+   +  G++    +S+T  D+G Y C A N
Sbjct: 232  FNITCETEGLPAPNITWKKNGVALPVDGRM---YARGHILFIAESLT-RDSGVYICEATN 287

Query: 989  AIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGP 1048
              G     + L ++   + +  +        +Q LE+    S  TE          ++  
Sbjct: 288  IAGSKQAKSELKVIAPVEPVITAT-------VQRLEELRPVSITTEVG-------SYIRT 333

Query: 1049 LKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASV 1108
            L+ +N  +      F   V         + W   G+ I +      Y         I + 
Sbjct: 334  LETSNLTLVCTVRGFPLPV---------ISWRRGGQAINNTQSALRYR--------IENA 376

Query: 1109 RAEDSGVYTVVARNAAGEAQLSASMT-VETRSSIDTSSIHRGLYEKTRHIEESKFVEPMY 1167
            R +D+G+YT VARN  G    S++++ V  +  I  +S H        H+        + 
Sbjct: 377  RVKDTGIYTCVARNLVGYDYSSSNISIVAAKPPIIRTSTH--------HLT-------VL 421

Query: 1168 QIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFK 1227
            + ++IS      V  LS       G  + L C     G P+ ++ W+ +G ++ V     
Sbjct: 422  RRDKISTDLGKNVTTLS-------GNTVSLLCNAT--GVPSPKLSWYKDGETLNVSH--- 469

Query: 1228 TYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQ 1287
                     L +   + +D+G Y   A N  G     + + V+  S     T +E   E 
Sbjct: 470  -------AVLTLPTLSPSDSGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTTSENITET 522

Query: 1288 IQLLEDAARRTKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWF 1347
                E+ A     +  D+                T+  +NV + C ++  G     + W 
Sbjct: 523  ----ENIAYIVTGIGSDVI---------------TLLSSNVEVTCPVR--GFPLPSITWL 561

Query: 1348 CNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
             +G+P+K     +         L LLS+    +G+Y C ATN LG A  +  L V+
Sbjct: 562  KDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATATTTLNVL 615



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I W KNGV L    R+ +    G +     SL  D SG+Y C+ATN+ G   + + 
Sbjct: 242  PAPNITWKKNGVALPVDGRMYAR---GHILFIAESLTRD-SGVYICEATNIAGSKQAKSE 297

Query: 2732 IKI 2734
            +K+
Sbjct: 298  LKV 300



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 4/81 (4%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           + L   E  PV L  +A G P P + W K G  ++     + H       L + +A   D
Sbjct: 14  ANLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLVS----KGHEIVAGGRLFLGKATLGD 69

Query: 558 AAWYQCTAQNVAGSTATRARL 578
           +  Y+CTA +  G  + ++ L
Sbjct: 70  SGEYECTATSPLGYVSAKSNL 90



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 6/112 (5%)

Query: 647 TAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDS 706
           TA    +I F    E  G P   I W KNG ++    R   ++  G+I     SL  +DS
Sbjct: 223 TARTLTRIIFNITCETEGLPAPNITWKKNGVALPVDGR---MYARGHILFIAESLT-RDS 278

Query: 707 GEYTCRAVSATGVAETKAVLHVTP--RATIERTSQHPETLQYIQQLEDYSKY 756
           G Y C A +  G  + K+ L V       I  T Q  E L+ +    +   Y
Sbjct: 279 GVYICEATNIAGSKQAKSELKVIAPVEPVITATVQRLEELRPVSITTEVGSY 330



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 31/192 (16%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P+ K+ W+K+G TL     +          L++ +L   DSG+Y C+A NL G   + + 
Sbjct: 452  PSPKLSWYKDGETLNVSHAV----------LTLPTLSPSDSGLYRCEARNLKGVDDADSY 501

Query: 2732 IKIEDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXXXVFISHLNNIVCKEGDNI 2791
            + +     L+G    P S+                        +     ++++     N+
Sbjct: 502  LTV-----LVGS---PPSI---------RTTSENITETENIAYIVTGIGSDVITLLSSNV 544

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851
               C V     P   I W  + +PL      K  +     +L +    E  +G+Y C AT
Sbjct: 545  EVTCPVRGF--PLPSITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVAT 600

Query: 2852 NSKGSATTSGSL 2863
            NS G+AT + +L
Sbjct: 601  NSLGAATATTTL 612



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 78/352 (22%), Positives = 137/352 (38%), Gaps = 73/352 (20%)

Query: 1077 VEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            + W  NG  +    R+      G++ L IA     DSGVY   A N AG  Q  + + V 
Sbjct: 246  ITWKKNGVALPVDGRMYAR---GHI-LFIAESLTRDSGVYICEATNIAGSKQAKSELKVI 301

Query: 1137 TR-SSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNI 1195
                 + T+++ R        +EE   + P+    E+      +++ L       E  N+
Sbjct: 302  APVEPVITATVQR--------LEE---LRPVSITTEVGS----YIRTL-------ETSNL 339

Query: 1196 HLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAV 1255
             L C +   G P   + W   G+++        Y         I +A   DTG YT  A 
Sbjct: 340  TLVCTVR--GFPLPVISWRRGGQAINNTQSALRYR--------IENARVKDTGIYTCVAR 389

Query: 1256 NHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAPQFSR 1315
            N +G  ++S+ + ++     +  T                         +TV++  + S 
Sbjct: 390  NLVGYDYSSSNISIVAAKPPIIRTSTHH---------------------LTVLRRDKIST 428

Query: 1316 AL-HNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLS 1374
             L  N+ T+ G  V L C     G  + ++ W+ +G+ +   H            L L +
Sbjct: 429  DLGKNVTTLSGNTVSLLCNA--TGVPSPKLSWYKDGETLNVSH----------AVLTLPT 476

Query: 1375 VYPEDSGVYTCQATNQLG--EAVTSCALRVIAKKDLILESQHPSGLEKIQYL 1424
            + P DSG+Y C+A N  G  +A +   + V +   +   S++ +  E I Y+
Sbjct: 477  LSPSDSGLYRCEARNLKGVDDADSYLTVLVGSPPSIRTTSENITETENIAYI 528



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 30/132 (22%), Positives = 56/132 (42%), Gaps = 8/132 (6%)

Query: 1466 CKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLV 1525
            C+ E +   N  + W KNG  + +  R   ++  G++ L I + +  DSG+Y C A N+ 
Sbjct: 236  CETEGLPAPN--ITWKKNGVALPVDGR---MYARGHI-LFIAESLTRDSGVYICEATNIA 289

Query: 1526 GTDEVSCRLTCRSTTD--IVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTS 1583
            G+ +    L   +  +  I  + Q    L  + +  +   Y RT     +T    +    
Sbjct: 290  GSKQAKSELKVIAPVEPVITATVQRLEELRPVSITTEVGSYIRTLETSNLTLVCTVRGFP 349

Query: 1584 LKNVEIKEGQRA 1595
            L  +  + G +A
Sbjct: 350  LPVISWRRGGQA 361



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 279 EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTL 338
           E A      + +G P P V W K G++L+ S  HEI+       L +      DSG Y  
Sbjct: 20  EKAPVTLTCKATGLPLPTVRWIKGGRQLV-SKGHEIVAGGR---LFLGKATLGDSGEYEC 75

Query: 339 LAENPNGCIVTSGYLAVESP 358
            A +P G +     L ++ P
Sbjct: 76  TATSPLGYVSAKSNLEIKVP 95



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 4/63 (6%)

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           G P P ITW+K+GV +  +   R++  G    L I  +   D+  Y C A N+AGS   +
Sbjct: 240 GLPAPNITWKKNGVALPVDG--RMYARG--HILFIAESLTRDSGVYICEATNIAGSKQAK 295

Query: 576 ARL 578
           + L
Sbjct: 296 SEL 298



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 5/95 (5%)

Query: 388 KALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447
           K L P  V +  +    E       C+ TG P P V W    RQ+     H+I+   +G 
Sbjct: 3   KNLEPVSVLIGANLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLVSK-GHEIV---AGG 58

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
             L +   TL DSG   C A +  G  + +  L +
Sbjct: 59  R-LFLGKATLGDSGEYECTATSPLGYVSAKSNLEI 92



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 2945 IEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            I W  +G+ L+Q    K+ +  G  TL L+ + ER +G+Y C A N  G A  ++T+
Sbjct: 558  ITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATATTTL 612



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 2/73 (2%)

Query: 2662 LEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            +E     R  P   I W K+G  L     +K     G  TL + S+    +G+Y C ATN
Sbjct: 544  VEVTCPVRGFPLPSITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATN 601

Query: 2722 LLGEAVSTASIKI 2734
             LG A +T ++ +
Sbjct: 602  SLGAATATTTLNV 614



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 2/63 (3%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            G P   I W  +G+P      V   N  G   L +  I  R AG Y C ATN  G+AT T
Sbjct: 552  GFPLPSITWLKDGQPLKQSMTVKVNNLTG--TLYLLSILERRAGLYMCVATNSLGAATAT 609

Query: 3783 AKI 3785
              +
Sbjct: 610  TTL 612



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 4/81 (4%)

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
            F+   E  G P   I W  NG       R++      FIA  +     RD+G Y C ATN
Sbjct: 232  FNITCETEGLPAPNITWKKNGVALPVDGRMYARGHILFIAESL----TRDSGVYICEATN 287

Query: 3775 KWGSATTTAKITCSAKRDIVL 3795
              GS    +++   A  + V+
Sbjct: 288  IAGSKQAKSELKVIAPVEPVI 308



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 4/83 (4%)

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
            ++  +E  P     + T    PT++W++ G  +  +   +++  G    L +G     D+
Sbjct: 15   NLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLV-SKGHEIVAGGR---LFLGKATLGDS 70

Query: 4789 GTFTCRATTAAGQVETSAKLVVK 4811
            G + C AT+  G V   + L +K
Sbjct: 71   GEYECTATSPLGYVSAKSNLEIK 93



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 6/75 (8%)

Query: 2791 IHFECNVEPSRDPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCK 2849
            I F    E    P   I W  N   LP  G  Y   H      L I  +   DSG+Y C+
Sbjct: 230  IIFNITCETEGLPAPNITWKKNGVALPVDGRMYARGH-----ILFIAESLTRDSGVYICE 284

Query: 2850 ATNSKGSATTSGSLR 2864
            ATN  GS      L+
Sbjct: 285  ATNIAGSKQAKSELK 299



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 71/322 (22%), Positives = 122/322 (37%), Gaps = 69/322 (21%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595
            G P+    W  NGV L +  R        F+   +      D+G+Y+C+A N AG     
Sbjct: 240  GLPAPNITWKKNGVALPVDGRMYARGHILFIAESLT----RDSGVYICEATNIAGSKQAK 295

Query: 2596 XXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPI-FTTHLKSYDKL 2654
                       +   + P       +  A + ++ E+         P+  TT + SY + 
Sbjct: 296  SELK-------VIAPVEP-------VITATVQRLEEL--------RPVSITTEVGSYIRT 333

Query: 2655 VEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714
            +E  ++ L   V  R  P   I W + G  +      +S   +      I + R  D+GI
Sbjct: 334  LETSNLTLVCTV--RGFPLPVISWRRGGQAINN---TQSALRY-----RIENARVKDTGI 383

Query: 2715 YTCKATNLLGEAVSTASIKI-EDRHWLLGESLHPDSLDRIGALXXXXXXXXXXXXXXXXX 2773
            YTC A NL+G   S+++I I   +  ++  S H  ++ R   +                 
Sbjct: 384  YTCVARNLVGYDYSSSNISIVAAKPPIIRTSTHHLTVLRRDKISTDLG------------ 431

Query: 2774 XVFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSL 2833
                    N+    G+ +   CN   +  P+ K+ W+ + + L          + S+  L
Sbjct: 432  -------KNVTTLSGNTVSLLCNA--TGVPSPKLSWYKDGETL----------NVSHAVL 472

Query: 2834 DITHTYEEDSGIYTCKATNSKG 2855
             +      DSG+Y C+A N KG
Sbjct: 473  TLPTLSPSDSGLYRCEARNLKG 494



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 35/132 (26%), Positives = 49/132 (37%), Gaps = 4/132 (3%)

Query: 3788 SAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGV 3847
            SA+R + L   LP  +   +         S    +E I S     +  +   T      +
Sbjct: 171  SAERSLHLPDILPNALLSARHSAEPPIPPSIKTSDEIIESLKRDPLGLVIGQTARTLTRI 230

Query: 3848 RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAV 3907
             F    E +  P   I W +NG  LP   R   +Y  G + L I      DSG YIC A 
Sbjct: 231  IFNITCETEGLPAPNITWKKNGVALPVDGR---MYARGHI-LFIAESLTRDSGVYICEAT 286

Query: 3908 NDFGEDFTKATI 3919
            N  G    K+ +
Sbjct: 287  NIAGSKQAKSEL 298



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 6/101 (5%)

Query: 3312 PDLKVEWFYNGKKLP-HGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
            P   + W  NG  LP  G  Y   H     IL I      +SG Y C ATN  G    K+
Sbjct: 242  PAPNITWKKNGVALPVDGRMYARGH-----ILFIAESLTRDSGVYICEATNIAGSKQAKS 296

Query: 3371 NLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMVRRKDTS 3411
             LK  +    ++ + + R  E     + T   S +R  +TS
Sbjct: 297  ELKVIAPVEPVITATVQRLEELRPVSITTEVGSYIRTLETS 337



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 7/81 (8%)

Query: 3082 IEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            I W  NG  +    R+   YA G ++  I  + T DSG Y C ATN  G  +   +L+ +
Sbjct: 246  ITWKKNGVALPVDGRM---YARGHILF-IAESLTRDSGVYICEATNIAGSKQAKSELKVI 301

Query: 3142 DKSKGQKPRFTTHIQNIEGLK 3162
                  +P  T  +Q +E L+
Sbjct: 302  ---APVEPVITATVQRLEELR 319



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 4/65 (6%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   + W+K G+ + +      I   G + L   +L   DSGEY C A S  G    K
Sbjct: 32  GLPLPTVRWIKGGRQLVSKGH--EIVAGGRLFLGKATLG--DSGEYECTATSPLGYVSAK 87

Query: 724 AVLHV 728
           + L +
Sbjct: 88  SNLEI 92



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 2/63 (3%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P   + W KDG+P+  S  +T   N    +L ++ +    AG Y   A N LG A +T +
Sbjct: 554 PLPSITWLKDGQPLKQS--MTVKVNNLTGTLYLLSILERRAGLYMCVATNSLGAATATTT 611

Query: 860 IRV 862
           + V
Sbjct: 612 LNV 614



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 14/23 (60%), Positives = 18/23 (78%)

Query: 3351 NSGEYECVATNKLGRDSTKANLK 3373
            +SGEYEC AT+ LG  S K+NL+
Sbjct: 69   DSGEYECTATSPLGYVSAKSNLE 91



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 12/85 (14%)

Query: 644 KSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNI 703
           K+VT + G  +         G P+ K+ W K+G+++  S          +  L + +L+ 
Sbjct: 432 KNVTTLSGNTVSL--LCNATGVPSPKLSWYKDGETLNVS----------HAVLTLPTLSP 479

Query: 704 QDSGEYTCRAVSATGVAETKAVLHV 728
            DSG Y C A +  GV +  + L V
Sbjct: 480 SDSGLYRCEARNLKGVDDADSYLTV 504



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 4/99 (4%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P   L   N+       V L  K TG     V W+K G+++     +K  E      L +
Sbjct: 7    PVSVLIGANLTAFEKAPVTLTCKATGLPLPTVRWIKGGRQLV----SKGHEIVAGGRLFL 62

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
             +A   DSG+YEC A +  G     +   + +P +   P
Sbjct: 63   GKATLGDSGEYECTATSPLGYVSAKSNLEIKVPFSFHHP 101



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 8/72 (11%)

Query: 2131 CRVEPINDPHLTIDWFHNGQKIRA-GHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNK 2189
            C  E +  P++T  W  NG  +   G  Y   H      L I  +   DSG Y+C+ATN 
Sbjct: 236  CETEGLPAPNIT--WKKNGVALPVDGRMYARGH-----ILFIAESLTRDSGVYICEATNI 288

Query: 2190 LGEAVNTCTLKV 2201
             G       LKV
Sbjct: 289  AGSKQAKSELKV 300



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 10/59 (16%)

Query: 95  LRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           +RG P PV+SW R+    +   + ++RY  +   V          D G YTC ARN  G
Sbjct: 345 VRGFPLPVISW-RRGGQAINNTQSALRYRIENARVK---------DTGIYTCVARNLVG 393



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            T D++ +  K+ P   V   Q+  +L  +      C+   +  PN  + W  NG  L   
Sbjct: 203  TSDEIIESLKRDPLGLVIG-QTARTLTRI-IFNITCETEGLPAPN--ITWKKNGVALPVD 258

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIK 4064
             R   +Y  G++          DSG Y+C ATN+ G  + K+ +K
Sbjct: 259  GR---MYARGHILF-IAESLTRDSGVYICEATNIAGSKQAKSELK 299



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 4/68 (5%)

Query: 88  NAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCT 147
           N +    +RG P P ++W +   PL +    +++ N  TG + LL   I     G Y C 
Sbjct: 543 NVEVTCPVRGFPLPSITWLKDGQPLKQ--SMTVKVNNLTGTLYLL--SILERRAGLYMCV 598

Query: 148 ARNQYGEA 155
           A N  G A
Sbjct: 599 ATNSLGAA 606


>SB_52575| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1267

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 79/316 (25%), Positives = 134/316 (42%), Gaps = 42/316 (13%)

Query: 4503 KRRQGRGGIV--PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN 4560
            K  +G  GI    P+ T   +++   +G+ + L     G     + W +    + P  R+
Sbjct: 247  KGEKGDAGISVRAPTITQPPKSLITIAGETIFLTCSSEGLPSPKIDWGRVSGTL-PSGRH 305

Query: 4561 KILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAAN 4620
             ++  +GT  L  L +   D G Y CVA N  G+AR  A   V +P          + A+
Sbjct: 306  -VVHSNGTLALTQLRS--GDEGLYACVAKNVLGKARAFASVGVLVPI---------QMAH 353

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
             P       +D++V +   +  +C+  G P P   WY+ ++++        + T+D  + 
Sbjct: 354  KP-------EDQVVQDNSTVMLNCQATGFPDPNYTWYRNNQVL-------TTLTSDNGSF 399

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             I++A  +D G Y C A N    V   AKL V +         LTP   +  + G     
Sbjct: 400  IITKATADDSGVYVCAAKNMLNEVRATAKLIVARLLSF----TLTPPAVLQAHAGAKVIL 455

Query: 4741 KTQITS-KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
              Q  S  + P I+WLR G  + +      +H  +N  L +  T   D GT+ C A    
Sbjct: 456  NCQADSGLLVPRIKWLRAGKHVTDG-----VH--SNGSLEVNVTSLADEGTYACVAENDV 508

Query: 4800 G-QVETSAKLVVKSKT 4814
            G ++ +S ++ V  +T
Sbjct: 509  GAKINSSCEVKVYFRT 524



 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
           +D+ V +      +C+ TG P P  TW+ N        N  +    S N + +IT  T  
Sbjct: 356 EDQVVQDNSTVMLNCQATGFPDPNYTWYRN--------NQVLTTLTSDNGSFIITKATAD 407

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIE-KEQVVAPKFVERFSTLNVREGEPVVLNARA-VG 516
           DSGV  C A+N   E     +L V       + P  V     L    G  V+LN +A  G
Sbjct: 408 DSGVYVCAAKNMLNEVRATAKLIVARLLSFTLTPPAV-----LQAHAGAKVILNCQADSG 462

Query: 517 TPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
              PRI W + G  +       +H++G   +L++     +D   Y C A+N  G+
Sbjct: 463 LLVPRIKWLRAGKHVTDG----VHSNG---SLEVNVTSLADEGTYACVAENDVGA 510



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 64/279 (22%), Positives = 113/279 (40%), Gaps = 43/279 (15%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            +G P P I W R +  + +      H   +   L + Q+   D  ++A VA+N  G A+ 
Sbjct: 284  EGLPSPKIDWGRVSGTLPSGR----HVVHSNGTLALTQLRSGDEGLYACVAKNVLGKARA 339

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
             A++          G +VP       ++  V     V L+ + TG    +  W +N +  
Sbjct: 340  FASV----------GVLVPIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYTWYRNNQ-- 387

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
               +   +  ++G++  +I +A   DSG Y C A N   E R  A+ +V+   +     P
Sbjct: 388  ---VLTTLTSDNGSF--IITKATADDSGVYVCAAKNMLNEVRATAKLIVARLLSFTLTPP 442

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
                A+A          K++   QA        G  +P ++W +  K +    +   S  
Sbjct: 443  AVLQAHAGA--------KVILNCQADS------GLLVPRIKWLRAGKHVTDGVHSNGS-- 486

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAG-RVTVAAKLKV 4712
                 L ++     DEG Y CVA N  G ++  + ++KV
Sbjct: 487  -----LEVNVTSLADEGTYACVAENDVGAKINSSCEVKV 520



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 47/173 (27%), Positives = 76/173 (43%), Gaps = 17/173 (9%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G+     C   G P P++ W    R      + + +V+ +G  AL  T +   D G+  C
Sbjct: 274 GETIFLTCSSEGLPSPKIDW---GRVSGTLPSGRHVVHSNGTLAL--TQLRSGDEGLYAC 328

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
           VA+N  G+      + V+   Q +A K  ++     V++   V+LN +A G P P  TW 
Sbjct: 329 VAKNVLGKARAFASVGVLVPIQ-MAHKPEDQV----VQDNSTVMLNCQATGFPDPNYTWY 383

Query: 526 KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           ++      N  L   T    S + I +A A D+  Y C A+N+       A+L
Sbjct: 384 RN------NQVLTTLTSDNGSFI-ITKATADDSGVYVCAAKNMLNEVRATAKL 429



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 8/101 (7%)

Query: 2635 DTGVQ-QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKS 2693
            D G+  +AP  T   KS   +  G+ ++L    E    P  KI+W +   TL +G  +  
Sbjct: 252  DAGISVRAPTITQPPKSLITIA-GETIFLTCSSEGLPSP--KIDWGRVSGTLPSGRHVVH 308

Query: 2694 TFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +      TL++  LR+ D G+Y C A N+LG+A + AS+ +
Sbjct: 309  SNG----TLALTQLRSGDEGLYACVAKNVLGKARAFASVGV 345



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 12/101 (11%)

Query: 2633 FVDTGVQQAPIFTTHLKSYDKLVEGQH-VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARL 2691
            F   GV   PI   H K  D++V+    V L  Q     DPN    W++N   LTT    
Sbjct: 340  FASVGVL-VPIQMAH-KPEDQVVQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT---- 391

Query: 2692 KSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
              T D G  +  I     DDSG+Y C A N+L E  +TA +
Sbjct: 392  -LTSDNG--SFIITKATADDSGVYVCAAKNMLNEVRATAKL 429



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 7/84 (8%)

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
           S+G + P ++A KP +  +Q+ +      Q +G P P  TW++N Q L        +T+ 
Sbjct: 342 SVGVLVPIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYTWYRNNQVLTT------LTSD 395

Query: 319 NHTTLRVRNTQKSDSGHYTLLAEN 342
           N + +  + T   DSG Y   A+N
Sbjct: 396 NGSFIITKAT-ADDSGVYVCAAKN 418



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 5/103 (4%)

Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKD 527
           R + GET F+          V AP   +   +L    GE + L   + G P+P+I W + 
Sbjct: 238 RGERGETGFKGEKGDAGIS-VRAPTITQPPKSLITIAGETIFLTCSSEGLPSPKIDWGRV 296

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
               +P+    +H++G   TL + + ++ D   Y C A+NV G
Sbjct: 297 S-GTLPSGRHVVHSNG---TLALTQLRSGDEGLYACVAKNVLG 335



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 7/98 (7%)

Query: 2362 FKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIED 2421
            FK  +    ++ + P  TQP +++  I  G+T    C     G P+ K++W R    +  
Sbjct: 246  FKGEKGDAGISVRAPTITQPPKSLITIA-GETIFLTCS--SEGLPSPKIDWGRVSGTLPS 302

Query: 2422 SSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
               +   H  G +++T   +R  DEG+Y C A N+LG+
Sbjct: 303  GRHVV--HSNGTLALT--QLRSGDEGLYACVAKNVLGK 336



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 51/193 (26%), Positives = 76/193 (39%), Gaps = 24/193 (12%)

Query: 3046 RPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGM 3105
            R P  T   K ++ I+ G+      S    G  S  I+W     T+ +   +  V++ G 
Sbjct: 258  RAPTITQPPKSLITIA-GETIFLTCS--SEGLPSPKIDWGRVSGTLPSGRHV--VHSNGT 312

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            + L  L  ++ D G Y+C A N  G+A     +  +       P    H    + ++D  
Sbjct: 313  LALTQL--RSGDEGLYACVAKNVLGKARAFASVGVL------VPIQMAHKPEDQVVQDNS 364

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            +    C      DP+    WY N Q +   T     SD G  ++  A     DSG YVC 
Sbjct: 365  TVMLNCQATGFPDPNYT--WYRNNQVLTTLT-----SDNGSFIITKATAD--DSGVYVCA 415

Query: 3226 AYNKYGEDFTRAT 3238
            A N   E   RAT
Sbjct: 416  AKNMLNE--VRAT 426



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 9/72 (12%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            +Q+  T   +C+     DP     W+RN +++      T T D G  S  I+    +D G
Sbjct: 360  VQDNSTVMLNCQATGFPDPNYT--WYRNNQVLT-----TLTSDNG--SFIITKATADDSG 410

Query: 2448 VYMCRASNLLGE 2459
            VY+C A N+L E
Sbjct: 411  VYVCAAKNMLNE 422



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 57/257 (22%), Positives = 90/257 (35%), Gaps = 30/257 (11%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA- 155
           G P+P + W R    L    ++ +  N      +L + Q+  GDEG Y C A+N  G+A 
Sbjct: 285 GLPSPKIDWGRVSGTLPS-GRHVVHSNG-----TLALTQLRSGDEGLYACVAKNVLGKAR 338

Query: 156 -ICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGTD 214
              SV +                    V    +   +    YT  ++ Q      ++   
Sbjct: 339 AFASVGVLVPIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYTWYRNNQVLTTLTSDNGS 398

Query: 215 HSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLG-PVSPPKIAQKPR 273
              T     D+  Y             K  + E        + R L   ++PP + Q   
Sbjct: 399 FIITKATADDSGVY---------VCAAKNMLNEVRATAKLIVARLLSFTLTPPAVLQAHA 449

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
            +K+     A      SG   PR+ W + G       KH     H++ +L V  T  +D 
Sbjct: 450 GAKVILNCQAD-----SGLLVPRIKWLRAG-------KHVTDGVHSNGSLEVNVTSLADE 497

Query: 334 GHYTLLAENPNGCIVTS 350
           G Y  +AEN  G  + S
Sbjct: 498 GTYACVAENDVGAKINS 514



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 9/116 (7%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            P +    P D ++ +NS+    C+     D +    W+ N + L T     T ++  F+I
Sbjct: 348  PIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT----LTSDNGSFII 401

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESI 3672
             +       D+G+Y C A N   E   + KL V       L P       +G + I
Sbjct: 402  TKATA---DDSGVYVCAAKNMLNEVRATAKLIVARLLSFTLTPPAVLQAHAGAKVI 454



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 9/81 (11%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSG 1915
            + +  +    C+   +PDPN    WY N +VL +     TS++  F    I     +DSG
Sbjct: 360  VQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT----LTSDNGSFI---ITKATADDSG 410

Query: 1916 EYTCKAINNLGQAVSSIRLNV 1936
             Y C A N L +  ++ +L V
Sbjct: 411  VYVCAAKNMLNEVRATAKLIV 431



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 6/90 (6%)

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            D  ++++   +T+P      I G+ +   C  E +     K++W +    +  G     +
Sbjct: 252  DAGISVRAPTITQPPKSLITIAGETIFLTCSSEGLPSP--KIDWGRVSGTLPSGRHV--V 307

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVG 1526
            H  G +AL    L + D G+Y C A N++G
Sbjct: 308  HSNGTLALT--QLRSGDEGLYACVAKNVLG 335



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 9/82 (10%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSG 2180
            +++       C+     DP+ T  W+ N Q +        T D G  +  I    A+DSG
Sbjct: 360  VQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT-----LTSDNG--SFIITKATADDSG 410

Query: 2181 TYMCKATNKLGEAVNTCTLKVA 2202
             Y+C A N L E   T  L VA
Sbjct: 411  VYVCAAKNMLNEVRATAKLIVA 432



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 6/82 (7%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEE 2841
            +++   G+ I   C+ E    P  KI+W   +  LPSG     ++     +L +T     
Sbjct: 268  SLITIAGETIFLTCSSEGLPSP--KIDWGRVSGTLPSGRHVVHSNG----TLALTQLRSG 321

Query: 2842 DSGIYTCKATNSKGSATTSGSL 2863
            D G+Y C A N  G A    S+
Sbjct: 322  DEGLYACVAKNVLGKARAFASV 343



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 9/87 (10%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  P +   + +   V+++  V   C+     DP     WYRN ++L +        D G
Sbjct: 345  VLVPIQMAHKPEDQVVQDNSTVMLNCQATGFPDPNYT--WYRNNQVLTT-----LTSDNG 397

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGE 3912
              S  I    A+DSG Y+C A N   E
Sbjct: 398  --SFIITKATADDSGVYVCAAKNMLNE 422



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 4/83 (4%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           V  P I Q P++     G          G P P++ W +    L  S +H +   H++ T
Sbjct: 257 VRAPTITQPPKSLITIAGETIFLTCSSEGLPSPKIDWGRVSGTL-PSGRHVV---HSNGT 312

Query: 323 LRVRNTQKSDSGHYTLLAENPNG 345
           L +   +  D G Y  +A+N  G
Sbjct: 313 LALTQLRSGDEGLYACVAKNVLG 335



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 4/52 (7%)

Query: 2152 IRAG-HRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVN-TCTLKV 2201
            +RAG H     H  G  +L++  T   D GTY C A N +G  +N +C +KV
Sbjct: 471  LRAGKHVTDGVHSNG--SLEVNVTSLADEGTYACVAENDVGAKINSSCEVKV 520


>SB_41626| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 753

 Score = 69.3 bits (162), Expect = 7e-11
 Identities = 77/320 (24%), Positives = 124/320 (38%), Gaps = 46/320 (14%)

Query: 4520 AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI-LEEDGTYTLL----IL 4574
            +  V +  G  + L+ K      +D+ W +  ++  P  R  + +E+D  Y ++    I+
Sbjct: 9    SNKVTLDEGSTLTLECKANIDDFLDIGWERKDQRTLPSNRTVLDVEDDDGYFIIKRLSIV 68

Query: 4575 EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV 4634
            +  P D+G Y C        A  D E  V+     +   PQ   AN            ++
Sbjct: 69   DMLPSDAGVYTCQGWTYNSSAPSDVEVKVN-----EFVSPQVSLANL----------SVI 113

Query: 4635 AEGQAIEFSCKIV-GKPLPTVQWYK-GDKLIK------------PSKYFQMSRTADEYT- 4679
            +  + +E  C+I+ G P P V WYK G  L              P+  +     A  YT 
Sbjct: 114  SSQKQVELKCQILAGYPTPQVSWYKDGTPLTPKPLGPRRNCTSFPTGVYYYDEYAPPYTR 173

Query: 4680 --LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
              +  +  F +  G Y C A N   R      L V +         + P  DI++  G+ 
Sbjct: 174  VLVLCNPRFLQSTGWYTCGAENVRNRTRDTKYLNVFESPTV----TIDPNHDIIINIGES 229

Query: 4738 AQFKTQITSKIKPTIQWLRE---GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
             + +   T    P + WL E   G ++P  P      EG + V++     E D G +TC 
Sbjct: 230  LELRCFATGNPTPEVIWLHELENGEVVPVDPGHVFSVEG-SLVVIKPRIEENDYGPYTCH 288

Query: 4795 ATTAAGQVETSAKLVVKSKT 4814
            A+   G    SA LV+   T
Sbjct: 289  ASNRHGNTTKSA-LVLSGTT 307



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 35/141 (24%), Positives = 55/141 (39%), Gaps = 6/141 (4%)

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
           L  +G  TC A N    T     LNV E   V     ++    + +  GE + L   A G
Sbjct: 183 LQSTGWYTCGAENVRNRTRDTKYLNVFESPTVT----IDPNHDIIINIGESLELRCFATG 238

Query: 517 TPTPRITW--QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
            PTP + W  + +   ++P     + +  G+  +  PR + +D   Y C A N  G+T  
Sbjct: 239 NPTPEVIWLHELENGEVVPVDPGHVFSVEGSLVVIKPRIEENDYGPYTCHASNRHGNTTK 298

Query: 575 RARLYXXXXXXXXXXQKRLHL 595
            A +             + HL
Sbjct: 299 SALVLSGTTLAKKKVPDKPHL 319



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 13/148 (8%)

Query: 396 KVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH----A 449
           K+     VT  EG     +C+     + ++ W   D++        + V +   +     
Sbjct: 5   KITPSNKVTLDEGSTLTLECKANIDDFLDIGWERKDQRTLPSNRTVLDVEDDDGYFIIKR 64

Query: 450 LMITNVTLSDSGVVTCVA--RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
           L I ++  SD+GV TC     N S  +  + ++N     QV     +   S ++ ++   
Sbjct: 65  LSIVDMLPSDAGVYTCQGWTYNSSAPSDVEVKVNEFVSPQVS----LANLSVISSQKQVE 120

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNP 535
           +     A G PTP+++W KDG P+ P P
Sbjct: 121 LKCQILA-GYPTPQVSWYKDGTPLTPKP 147



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 4/91 (4%)

Query: 3698 TVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH---NGRPFATGSRVHTLNDFGFIA 3754
            TV I  N D+        + R    G+PT  + W H   NG         H  +  G + 
Sbjct: 213  TVTIDPNHDIIINIGESLELRCFATGNPTPEVIWLHELENGEVVPVDPG-HVFSVEGSLV 271

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +    I   D G YTC A+N+ G+ T +A +
Sbjct: 272  VIKPRIEENDYGPYTCHASNRHGNTTKSALV 302



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 9/92 (9%)

Query: 3558 PEFTTTPS-DLILSENSSAHFECRLIPVNDSSMRVEWFH---NGKPL-LTGSRVKTINDF 3612
            P  T  P+ D+I++   S    C      + +  V W H   NG+ + +    V ++   
Sbjct: 212  PTVTIDPNHDIIINIGESLELRC--FATGNPTPEVIWLHELENGEVVPVDPGHVFSVE-- 267

Query: 3613 GFVILEIGGVYQRDAGLYTCKATNRHGEATVS 3644
            G +++    + + D G YTC A+NRHG  T S
Sbjct: 268  GSLVVIKPRIEENDYGPYTCHASNRHGNTTKS 299



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 5/72 (6%)

Query: 406 GKMTRFDCRVTGRPYPEVTW---FINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           G+     C  TG P PEV W     N   +  D  H   V   G+  ++   +  +D G 
Sbjct: 227 GESLELRCFATGNPTPEVIWLHELENGEVVPVDPGHVFSV--EGSLVVIKPRIEENDYGP 284

Query: 463 VTCVARNKSGET 474
            TC A N+ G T
Sbjct: 285 YTCHASNRHGNT 296



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 9/83 (10%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR--FRPIHDFG 1500
            KP+    P +   + EG  +  ECK     D  L + W +  Q     +R       D G
Sbjct: 3    KPKIT--PSNKVTLDEGSTLTLECKAN--IDDFLDIGWERKDQRTLPSNRTVLDVEDDDG 58

Query: 1501 YVA---LDIIDLIAEDSGIYTCR 1520
            Y     L I+D++  D+G+YTC+
Sbjct: 59   YFIIKRLSIVDMLPSDAGVYTCQ 81


>SB_53570| Best HMM Match : Y_phosphatase (HMM E-Value=0)
          Length = 2064

 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 53/175 (30%), Positives = 73/175 (41%), Gaps = 11/175 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C VTG P P +TW+ N   IR+       +   G   +      +  +    C A N  G
Sbjct: 91  CNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRIGPLRAKIHKA-TYECEADNGVG 149

Query: 473 ETAFQCRLNVIEKEQVVA---PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
                    ++          P+  +  S    R G+ V     AVGTPTP ITW KD +
Sbjct: 150 PPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRL 209

Query: 530 PIIPN-PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG----STATRARLY 579
           PI+ N P + + +DG    L I   + SD   Y C A+N  G    S A  ARL+
Sbjct: 210 PIVLNDPRVSVLSDG--RKLRITDLRESDNGKYSCVARNALGMVFSSQAMPARLF 262



 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 81/304 (26%), Positives = 127/304 (41%), Gaps = 31/304 (10%)

Query: 4514 PSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPD-IRNKILEEDGTYTL 4571
            P+ TLT ++   VT G  V +   VTG+    + W KNG  ++   I+   +   G   +
Sbjct: 70   PTVTLTPKDFAGVTRG-FVYMICNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRI 128

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKD 4631
              L A    +  YEC A N  G    D+  ++   A+       TK A  P  I +    
Sbjct: 129  GPLRAKIHKA-TYECEADNGVGPPLRDSSTLIVHTAS-------TKPAGFP-RIAKHPSF 179

Query: 4632 KIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            K    G  + F+C  VG P P + W+K D+L       ++S  +D   LRI++    D G
Sbjct: 180  KQRRSGDDVTFTCAAVGTPTPNITWFK-DRLPIVLNDPRVSVLSDGRKLRITDLRESDNG 238

Query: 4692 DYKCVAYNSAGRV----TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
             Y CVA N+ G V     + A+L +           L P +D  V      + K      
Sbjct: 239  KYSCVARNALGMVFSSQAMPARLFIVVVRSKPEF-TLRP-QDKTVDPDTDVELKCSARGS 296

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAK 4807
              P+I W  +G+ I           G N  L+I     + +G ++C A +  G+V+  A 
Sbjct: 297  PTPSIVWEVDGSRI----------SGQNGELIIRGI--QRSGNYSCIADSNMGRVQAYAY 344

Query: 4808 LVVK 4811
            + V+
Sbjct: 345  VTVR 348



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 74/273 (27%), Positives = 110/273 (40%), Gaps = 37/273 (13%)

Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           P   P +   P++              ++G+P P +TW+KNG  +I +++ +I T     
Sbjct: 66  PYQTPTVTLTPKDFAGVTRGFVYMICNVTGSPMPTLTWYKNGS-VIRNSRIQIFTMPYGG 124

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
            +R+    ++     T   E  NG         V  P    ++D  S  I  T   +   
Sbjct: 125 LIRI-GPLRAKIHKATYECEADNG---------VGPP----LRDS-STLIVHTASTKPAG 169

Query: 382 RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQ--IRDDYNHK 439
              I++    P F +     DVT      F C   G P P +TWF  DR   + +D    
Sbjct: 170 FPRIAKH---PSFKQRRSGDDVT------FTCAAVGTPTPNITWF-KDRLPIVLNDPRVS 219

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSG----ETAFQCRLNVIEKEQVVAPKFVE 495
           +L   S    L IT++  SD+G  +CVARN  G      A   RL ++       P+F  
Sbjct: 220 VL---SDGRKLRITDLRESDNGKYSCVARNALGMVFSSQAMPARLFIVVVRS--KPEFTL 274

Query: 496 RFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
           R     V     V L   A G+PTP I W+ DG
Sbjct: 275 RPQDKTVDPDTDVELKCSARGSPTPSIVWEVDG 307



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 45/193 (23%), Positives = 78/193 (40%), Gaps = 29/193 (15%)

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTH 318
           S  P   P+IA+ P   + + G D  F     G P P +TWFK+   ++  N   +    
Sbjct: 164 STKPAGFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIV-LNDPRVSVLS 222

Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRE 378
           +   LR+ + ++SD+G Y+ +A N  G + +S  +    P   ++   RS+         
Sbjct: 223 DGRKLRITDLRESDNGKYSCVARNALGMVFSSQAM----PARLFIVVVRSK--------- 269

Query: 379 TEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
                        P+F    QD+ V         C   G P P + W ++  +I      
Sbjct: 270 -------------PEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRISGQNGE 316

Query: 439 KIL--VNESGNHA 449
            I+  +  SGN++
Sbjct: 317 LIIRGIQRSGNYS 329



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 70/280 (25%), Positives = 108/280 (38%), Gaps = 30/280 (10%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVE-DSAVFAAVAENR-GGTAK 4493
            G P+P + WY+    I+NS   QI T     ++ I  +  +   A +   A+N  G   +
Sbjct: 95   GSPMPTLTWYKNGSVIRNS-RIQIFTMPYGGLIRIGPLRAKIHKATYECEADNGVGPPLR 153

Query: 4494 CSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKK 4553
             S+ L+V     +  G    P            SG  V       GT   ++ W K+   
Sbjct: 154  DSSTLIVHTASTKPAGF---PRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLP 210

Query: 4554 -VQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
             V  D R  +L  DG   L I +    D+GKY CVA N+ G          ++PA     
Sbjct: 211  IVLNDPRVSVL-SDGR-KLRITDLRESDNGKYSCVARNALGMVFSSQ----AMPA----- 259

Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672
            +       + PE     +DK V     +E  C   G P P++ W             ++S
Sbjct: 260  RLFIVVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGS--------RIS 311

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                E  +R  +      G+Y C+A ++ GRV   A + V
Sbjct: 312  GQNGELIIRGIQR----SGNYSCIADSNMGRVQAYAYVTV 347



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 48/193 (24%), Positives = 77/193 (39%), Gaps = 14/193 (7%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASH-RIRTVYAFGMV 3106
            P  T   KD   ++ G +  Y    + TG     + W+ NG  I  S  +I T+   G++
Sbjct: 70   PTVTLTPKDFAGVTRGFV--YMICNV-TGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLI 126

Query: 3107 VLEILGTKTTDSGTYSCRATNKWG---QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
             +  L  K     TY C A N  G   +   ++ +          PR   H  + +  + 
Sbjct: 127  RIGPLRAKI-HKATYECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKH-PSFKQRRS 184

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPM-RHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            G    F C  V    P+  I W+ +  P+  +  R+  +SD     L I   +  D+G+Y
Sbjct: 185  GDDVTFTCAAVGTPTPN--ITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNGKY 240

Query: 3223 VCRAYNKYGEDFT 3235
             C A N  G  F+
Sbjct: 241  SCVARNALGMVFS 253



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 6/91 (6%)

Query: 71  PPIFEQIFKNARFAQ---GGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           P  F +I K+  F Q   G +  F     G PTP ++W + + P+V  +    R +  + 
Sbjct: 167 PAGFPRIAKHPSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIVLNDP---RVSVLSD 223

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
              L I  +   D G+Y+C ARN  G    S
Sbjct: 224 GRKLRITDLRESDNGKYSCVARNALGMVFSS 254



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 797 VSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIS 856
           V  PT  + W+KD  PI  +    S+ + G   L I  LR  D G Y+  A N LG   S
Sbjct: 195 VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR-KLRITDLRESDNGKYSCVARNALGMVFS 253

Query: 857 TASI 860
           + ++
Sbjct: 254 SQAM 257



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 45/187 (24%), Positives = 71/187 (37%), Gaps = 17/187 (9%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W+++  PI  + D ++   S    L I  +   D+  ++ VA N  G    S
Sbjct: 196  GTPTPNITWFKDRLPIVLN-DPRVSVLSDGRKLRITDLRESDNGKYSCVARNALGMVFSS 254

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQ 4555
              +         R     P FTL  Q+  V     V L     G+    + W  +G ++ 
Sbjct: 255  QAMPARLFIVVVRS---KPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRIS 311

Query: 4556 PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVS-LPATKDKPKP 4614
                       G    LI+    Q SG Y C+A ++ G  +  A   V  LP    +P  
Sbjct: 312  -----------GQNGELIIRGI-QRSGNYSCIADSNMGRVQAYAYVTVRLLPFAPSRPNA 359

Query: 4615 QTKAANA 4621
             +  ++A
Sbjct: 360  ASITSDA 366



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 4/65 (6%)

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT--DGGASTLDIPRAKASDAAWYQCTA 565
           V +     G+P P +TW K+G  +I N  ++I T   GG   +   RAK   A  Y+C A
Sbjct: 87  VYMICNVTGSPMPTLTWYKNG-SVIRNSRIQIFTMPYGGLIRIGPLRAKIHKAT-YECEA 144

Query: 566 QNVAG 570
            N  G
Sbjct: 145 DNGVG 149



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 2389 QEGQTAHFDCRLIPVGDPTLKVEWFRNE-KLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + G    F C    VG PT  + WF++   ++ +  R++   D     + I+ +R+ D G
Sbjct: 183  RSGDDVTFTCAA--VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNG 238

Query: 2448 VYMCRASNLLG 2458
             Y C A N LG
Sbjct: 239  KYSCVARNALG 249



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 12/92 (13%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           S P+   +P++  +    D + +    G+P P + W  +G R+   N  E+I        
Sbjct: 268 SKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRISGQN-GELI-------- 318

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
            +R  Q+  SG+Y+ +A++  G +    Y+ V
Sbjct: 319 -IRGIQR--SGNYSCIADSNMGRVQAYAYVTV 347



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 30/102 (29%), Positives = 41/102 (40%), Gaps = 4/102 (3%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVA 1503
            PR    P S +    G  V F C        N  + WFK+  P+ +      +   G   
Sbjct: 171  PRIAKHP-SFKQRRSGDDVTFTCAAVGTPTPN--ITWFKDRLPIVLNDPRVSVLSDGR-K 226

Query: 1504 LDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRS 1545
            L I DL   D+G Y+C A N +G    S  +  R    +VRS
Sbjct: 227  LRITDLRESDNGKYSCVARNALGMVFSSQAMPARLFIVVVRS 268



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 1/61 (1%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I WFK+ + +       S    G   L I  LR  D+G Y+C A N LG   S+ +
Sbjct: 198  PTPNITWFKDRLPIVLNDPRVSVLSDGR-KLRITDLRESDNGKYSCVARNALGMVFSSQA 256

Query: 2732 I 2732
            +
Sbjct: 257  M 257



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 5/79 (6%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLDITHTYEEDSG 2844
            + GD++ F C    +  PT  I WF +  P+  +  R     D     L IT   E D+G
Sbjct: 183  RSGDDVTFTCAAVGT--PTPNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNG 238

Query: 2845 IYTCKATNSKGSATTSGSL 2863
             Y+C A N+ G   +S ++
Sbjct: 239  KYSCVARNALGMVFSSQAM 257



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 25/69 (36%), Positives = 30/69 (43%), Gaps = 5/69 (7%)

Query: 3710 GGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGS-RVHTLNDFGFIALDIDYIYARDAGEY 3768
            G  V F C    VG PT  I WF +  P      RV  L+D     L I  +   D G+Y
Sbjct: 185  GDDVTFTCAA--VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNGKY 240

Query: 3769 TCRATNKWG 3777
            +C A N  G
Sbjct: 241  SCVARNALG 249



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 1/61 (1%)

Query: 936 IGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATT 995
           +G  T  + W KD  P+  +    +  + G   L I  +   D G Y+C A NA+G   +
Sbjct: 195 VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR-KLRITDLRESDNGKYSCVARNALGMVFS 253

Query: 996 S 996
           S
Sbjct: 254 S 254



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%)

Query: 663 VGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGV 719
           VG PT  I W K+   I  +    S+   G   L +  L   D+G+Y+C A +A G+
Sbjct: 195 VGTPTPNITWFKDRLPIVLNDPRVSVLSDGR-KLRITDLRESDNGKYSCVARNALGM 250


>SB_41623| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1604

 Score = 68.9 bits (161), Expect = 9e-11
 Identities = 60/205 (29%), Positives = 87/205 (42%), Gaps = 30/205 (14%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP--------DIRNKILE- 4564
            P+  L     N TS   V L   VTG  P  V W K+G+ + P        D +N+I E 
Sbjct: 1014 PTVRLDDLTTNETSS--VALQCHVTGNPPPTVRWYKDGRVLSPRLTLSSLKDCKNRINEL 1071

Query: 4565 -------EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTK 4617
                    + +YTL++ +A   DSG YEC A+NS G+ +      V +P +  + +P   
Sbjct: 1072 YHLDKRDNEESYTLVVCKASYNDSGSYECQAVNSLGQDKDQGYLDVQVPPSILRIEPDN- 1130

Query: 4618 AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE 4677
                   I +P+K      G+     C   G P P VQW K  +    +     S     
Sbjct: 1131 ------FIADPIK-----FGEVFYADCFATGNPTPKVQWKKETENGTFTAVVNSSAQNGH 1179

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAG 4702
              L  +    +D G+Y+CVA NS G
Sbjct: 1180 SRLYFASLREDDLGNYECVAVNSLG 1204



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 64/286 (22%), Positives = 113/286 (39%), Gaps = 38/286 (13%)

Query: 4538 TGTKPIDV--YWL-KNGKKVQPD----IRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            TG    D   YW+ K  ++++      +R+ +     T  L ++ A P D+G Y C A  
Sbjct: 934  TGHSAFDAPPYWVDKENRRIESSGRVSVRSIVRPLQNTTILEVVNASPNDTGHYTCAA-- 991

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
                 + +   +VS     +       A +AP   ++ L      E  ++   C + G P
Sbjct: 992  ----KKKNNRDIVSTSIFME-----VVAVSAPTVRLDDLTTN---ETSSVALQCHVTGNP 1039

Query: 4651 LPTVQWYKGDKLIKP--------------SKYFQMSRTADE--YTLRISEAFPEDEGDYK 4694
             PTV+WYK  +++ P              ++ + + +  +E  YTL + +A   D G Y+
Sbjct: 1040 PPTVRWYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDNEESYTLVVCKASYNDSGSYE 1099

Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
            C A NS G+      L V  P     +     + D + + G+        T    P +QW
Sbjct: 1100 CQAVNSLGQDKDQGYLDVQVPPSILRIEPDNFIADPIKF-GEVFYADCFATGNPTPKVQW 1158

Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             +E      T       +  ++ L   +  E+D G + C A  + G
Sbjct: 1159 KKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVNSLG 1204



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 46/194 (23%), Positives = 74/194 (38%), Gaps = 16/194 (8%)

Query: 400  DRDVTEGKMTRFDCRVTGRPYPEVTWFINDR---------QIRDDYN------HKILVNE 444
            D    E       C VTG P P V W+ + R          ++D  N      H    + 
Sbjct: 1020 DLTTNETSSVALQCHVTGNPPPTVRWYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDN 1079

Query: 445  SGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE 504
              ++ L++   + +DSG   C A N  G+   Q  L+V     ++  +  + F    ++ 
Sbjct: 1080 EESYTLVVCKASYNDSGSYECQAVNSLGQDKDQGYLDVQVPPSILRIE-PDNFIADPIKF 1138

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            GE    +  A G PTP++ W+K+         +      G S L     +  D   Y+C 
Sbjct: 1139 GEVFYADCFATGNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECV 1198

Query: 565  AQNVAGSTATRARL 578
            A N  G+     RL
Sbjct: 1199 AVNSLGTKKKIYRL 1212



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 52/183 (28%), Positives = 79/183 (43%), Gaps = 32/183 (17%)

Query: 422 EVTWFINDRQIRDDYNHKIL-------VNESG----NHALMITNVTLSDSGVVTCVARNK 470
           +VTW+    ++R D + KI         N +G     + L +TNVT  D+G   C  +N+
Sbjct: 601 DVTWY----RVRGDKSEKITKGVQQSETNSNGYLIITNELSLTNVTKEDAGSYMCEKKNR 656

Query: 471 SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVP 530
            G TA Q  + V   +       +E+ +  +  E E   +     G+P P+I+W + G+P
Sbjct: 657 IGATA-QASIYVPVLDTTKPSVNIEK-NNYSAEENEVSRIRCVVSGSPWPKISWYRGGIP 714

Query: 531 II-----PNPELRIHTDGG---------ASTLDIPRA-KASDAAWYQCTAQNVAGSTATR 575
           I+       PE       G          S L+I  +    D A + C A NVAGST   
Sbjct: 715 IVTCEGGQFPECPSRFSNGYRASVVKYSYSELEIKNSLYPRDNAMFACVATNVAGSTRDT 774

Query: 576 ARL 578
           A L
Sbjct: 775 AAL 777



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 39/137 (28%), Positives = 55/137 (40%), Gaps = 19/137 (13%)

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L + N + +D+G  TC A+ K+        +  +E   V AP    R   L   E   V 
Sbjct: 974  LEVVNASPNDTGHYTCAAKKKNNRDIVSTSI-FMEVVAVSAPTV--RLDDLTTNETSSVA 1030

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPEL--------RI----HTD----GGASTLDIPRA 553
            L     G P P + W KDG  + P   L        RI    H D      + TL + +A
Sbjct: 1031 LQCHVTGNPPPTVRWYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDNEESYTLVVCKA 1090

Query: 554  KASDAAWYQCTAQNVAG 570
              +D+  Y+C A N  G
Sbjct: 1091 SYNDSGSYECQAVNSLG 1107



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 70/321 (21%), Positives = 126/321 (39%), Gaps = 40/321 (12%)

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPID-VYWLKNGKKVQPDIRNKILEED-GT 4568
            +V P   +T   ++V  G  V L   V  +  +  V W K+  ++   +++   ++    
Sbjct: 118  LVKPRILVTPSQLSVVEGASVTLTCTVQASSQVGAVTWYKDATQLADGVQDYTSDDSLHK 177

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
             TL +      + G YEC   NS               +   +P   T+      +I+  
Sbjct: 178  NTLRLTNVGKDEGGMYECRVKNSFSYVN----------SYNAEP---TRLIVKEFKILSK 224

Query: 4629 LKDKIVA-EGQAIEFSCKIVGKPLPTVQ-W---YKG--DKLIKPSKYFQMSRTADEYTLR 4681
             +D ++A  G +++ +C I   P  TV  W   Y G   +L+       +  T  ++ L+
Sbjct: 225  SQDYLMAIVGDSLKVNC-ITSDPNATVSLWVKKYDGVPTRLVPDDDKLILKGT--KFVLQ 281

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVT--VAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739
              +    DEG Y C   N  G+V      +   +Q    D    + P   I+        
Sbjct: 282  --KVTLSDEGLYSCEGRNQRGKVVRKTMGQFIPSQGGYKDPKAHIYPSAKILPITNSSNF 339

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQM---IHEG---NNAVLLIGNTYEEDTGTFTC 4793
                +   I  T  WL+ G  +P      +   +H+G   N A+L+I +  ++D G +TC
Sbjct: 340  SCVALGDMI--TFSWLKNGTAVPANHVMILSPRVHQGHILNEALLMIRDARKDDAGIYTC 397

Query: 4794 RATTA---AGQVETSAKLVVK 4811
            R T+          +AKLV++
Sbjct: 398  RVTSGLQPGYSHSANAKLVIE 418



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 21/63 (33%), Positives = 31/63 (49%)

Query: 790  FEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVN 849
            F A      +PT +V+W K+    T ++ + S    G+  L    LR +D G+Y   AVN
Sbjct: 1142 FYADCFATGNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVN 1201

Query: 850  KLG 852
             LG
Sbjct: 1202 SLG 1204



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%)

Query: 2386 DNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDED 2445
            D I+ G+  + DC     G+PT KV+W +  +    ++ +  +   G+  +  + +R++D
Sbjct: 1134 DPIKFGEVFYADC--FATGNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDD 1191

Query: 2446 EGVYMCRASNLLG 2458
             G Y C A N LG
Sbjct: 1192 LGNYECVAVNSLG 1204



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 35/139 (25%), Positives = 55/139 (39%), Gaps = 27/139 (19%)

Query: 1857 SEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG-----------------HRYRTSNDF 1899
            +E  S   +C +   P P +R  WY +G+VL                    H  +  N+ 
Sbjct: 1024 NETSSVALQCHVTGNPPPTVR--WYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDNEE 1081

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
             +  +     Y  DSG Y C+A+N+LGQ      L+VQ   SI+R       +E   ++ 
Sbjct: 1082 SYTLVVCKASYN-DSGSYECQAVNSLGQDKDQGYLDVQVPPSILR-------IEPDNFIA 1133

Query: 1960 DDSRYKRAVQDDSFVVEKP 1978
            D  ++      D F    P
Sbjct: 1134 DPIKFGEVFYADCFATGNP 1152



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 58/258 (22%), Positives = 98/258 (37%), Gaps = 26/258 (10%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +LE++     D+G Y+C A  K  +  +S  +  ++      P  T  + ++    +  S
Sbjct: 973  ILEVVNASPNDTGHYTCAAKKKNNRDIVSTSI-FMEVVAVSAP--TVRLDDLT-TNETSS 1028

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
               +C V    +P   + WY +G+ +     + ++ D    + ++ +    D+ E     
Sbjct: 1029 VALQCHVT--GNPPPTVRWYKDGRVLSPRLTLSSLKDCKNRINELYHLDKRDNEE----- 1081

Query: 3227 YNKYGEDFTRATINCYGKGGVYLESLQPDSLAKIRELESLQGAQQQTPSTPSAEPPKFIT 3286
               Y     +A+   Y   G Y E    +SL + ++   L    Q  PS    EP  FI 
Sbjct: 1082 --SYTLVVCKAS---YNDSGSY-ECQAVNSLGQDKDQGYLD--VQVPPSILRIEPDNFIA 1133

Query: 3287 QIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILY 3346
               D  K  E     F A      +P  KV+W    +         +    G   L    
Sbjct: 1134 ---DPIKFGEV----FYADCFATGNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFAS 1186

Query: 3347 CYEENSGEYECVATNKLG 3364
              E++ G YECVA N LG
Sbjct: 1187 LREDDLGNYECVAVNSLG 1204



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 21/54 (38%), Positives = 26/54 (48%)

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLG 2724
            +P  K++W K     T  A + S+   G   L   SLR DD G Y C A N LG
Sbjct: 1151 NPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVNSLG 1204



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 18/55 (32%), Positives = 29/55 (52%)

Query: 664  GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718
            G+PT K++W K  ++   ++   S  + G+  L   SL   D G Y C AV++ G
Sbjct: 1150 GNPTPKVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVNSLG 1204



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 31/120 (25%), Positives = 43/120 (35%), Gaps = 4/120 (3%)

Query: 3113 TKTTDSGTYSCRATNKWGQAEI-SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFEC 3171
            T  TD G Y CR T   G+  + SV    V  S   KPR       +  + +G S    C
Sbjct: 84   TSNTDRGYYQCRTTLPDGRGRLESVGYITVFLSNLVKPRILVTPSQL-SVVEGASVTLTC 142

Query: 3172 TVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSD-FGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
            T V        + WY +   +    +  T  D      L +      + G Y CR  N +
Sbjct: 143  T-VQASSQVGAVTWYKDATQLADGVQDYTSDDSLHKNTLRLTNVGKDEGGMYECRVKNSF 201



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 41/160 (25%), Positives = 60/160 (37%), Gaps = 28/160 (17%)

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE 4627
            T  L +     +D+G Y C   N  G     A+  + +P   D  KP           IE
Sbjct: 633  TNELSLTNVTKEDAGSYMCEKKNRIGAT---AQASIYVPVL-DTTKPSVN--------IE 680

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK----------PSKY---FQMSRT 4674
               +    E +     C + G P P + WY+G   I           PS++   ++ S  
Sbjct: 681  K-NNYSAEENEVSRIRCVVSGSPWPKISWYRGGIPIVTCEGGQFPECPSRFSNGYRASVV 739

Query: 4675 ADEYT-LRISEA-FPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
               Y+ L I  + +P D   + CVA N AG     A L V
Sbjct: 740  KYSYSELEIKNSLYPRDNAMFACVATNVAGSTRDTAALNV 779



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 1/42 (2%)

Query: 1364 EFDYVALDLL-SVYPEDSGVYTCQATNQLGEAVTSCALRVIA 1404
            ++ Y  L++  S+YP D+ ++ C ATN  G    + AL V+A
Sbjct: 740  KYSYSELEIKNSLYPRDNAMFACVATNVAGSTRDTAALNVLA 781



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 41/192 (21%), Positives = 72/192 (37%), Gaps = 15/192 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           P+ +       V EG      C V        VTW+ +  Q+ D        +    + L
Sbjct: 121 PRILVTPSQLSVVEGASVTLTCTVQASSQVGAVTWYKDATQLADGVQDYTSDDSLHKNTL 180

Query: 451 MITNVTLSDSGVVTCVARNK-SGETAFQCR-LNVIEKEQVVAPKFVERFSTLNVREGEPV 508
            +TNV   + G+  C  +N  S   ++      +I KE  +  K  +    +    G+ +
Sbjct: 181 RLTNVGKDEGGMYECRVKNSFSYVNSYNAEPTRLIVKEFKILSKSQDYLMAI---VGDSL 237

Query: 509 VLNARAVGTPTPRIT-WQK--DGVP--IIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
            +N      P   ++ W K  DGVP  ++P+ + ++   G    L   +   SD   Y C
Sbjct: 238 KVNC-ITSDPNATVSLWVKKYDGVPTRLVPDDD-KLILKGTKFVLQ--KVTLSDEGLYSC 293

Query: 564 TAQNVAGSTATR 575
             +N  G    +
Sbjct: 294 EGRNQRGKVVRK 305



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/78 (29%), Positives = 31/78 (39%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTC 1536
            KV+W K  +  T           G+  L    L  +D G Y C AVN +GT +   RL  
Sbjct: 1155 KVQWKKETENGTFTAVVNSSAQNGHSRLYFASLREDDLGNYECVAVNSLGTKKKIYRLMS 1214

Query: 1537 RSTTDIVRSTQNEAGLEQ 1554
              T     S  N  G+ +
Sbjct: 1215 PPTAGKQLSRDNNVGISK 1232



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 16/79 (20%)

Query: 1461 HVHFECKLEPVTDSN----------LKVEWFKNGQPVTIGH------RFRPIHDFGYVAL 1504
            H++   K+ P+T+S+          +   W KNG  V   H      R    H      L
Sbjct: 323  HIYPSAKILPITNSSNFSCVALGDMITFSWLKNGTAVPANHVMILSPRVHQGHILNEALL 382

Query: 1505 DIIDLIAEDSGIYTCRAVN 1523
             I D   +D+GIYTCR  +
Sbjct: 383  MIRDARKDDAGIYTCRVTS 401


>SB_14313| Best HMM Match : I-set (HMM E-Value=1.8e-21)
          Length = 221

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 55/187 (29%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           AP F + + + RDV E K     C  +GRP P VTW +N        +   + + +GN  
Sbjct: 35  APAFNQPLDRSRDVAEDKDFSITCSASGRPAPNVTW-VNKT------SGSPVAHGTGNAT 87

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L +  +    +GV  C A N  G  A    + +     V  P  +       VR GE + 
Sbjct: 88  LSLLKIQRHQAGVYQCQAINNVGRGAITQDITI----NVQYPPEITPIQNTTVRAGETIT 143

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN-V 568
           L     G PTP ++W K G           H+ GG +      A  +D   Y CTA N V
Sbjct: 144 LTCAVAGNPTPSVSWSKAGSG---------HSTGG-NVFTRAGATKADTGQYVCTAVNTV 193

Query: 569 AGSTATR 575
            G+T T+
Sbjct: 194 TGNTQTK 200



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 49/215 (22%), Positives = 84/215 (39%), Gaps = 25/215 (11%)

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPL-KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKL 4662
            S P  +   +P+T      P   +PL + + VAE +    +C   G+P P V W      
Sbjct: 17   SEPFPEKFDEPKTAKNTKAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPNVTW------ 70

Query: 4663 IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
            +  +    ++      TL + +      G Y+C A N+ GR  +   + +         P
Sbjct: 71   VNKTSGSPVAHGTGNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITI----NVQYPP 126

Query: 4723 ALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGN 4782
             +TP+++  V  G+       +     P++ W + G+             G N     G 
Sbjct: 127  EITPIQNTTVRAGETITLTCAVAGNPTPSVSWSKAGS---------GHSTGGNVFTRAGA 177

Query: 4783 TYEEDTGTFTCRA-TTAAGQVET---SAKLVVKSK 4813
            T + DTG + C A  T  G  +T   S  ++VK K
Sbjct: 178  T-KADTGQYVCTAVNTVTGNTQTKTASTYVMVKCK 211



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 13/114 (11%)

Query: 2349 GLEKI-RELESAEPFKRPEIPEPVTRQR---PVFTQPLQNIDNIQEGQTAHFDCRLIPVG 2404
            G E I R   S+EPF   +  EP T +    P F QPL    ++ E +     C     G
Sbjct: 6    GYELITRTTASSEPFPE-KFDEPKTAKNTKAPAFNQPLDRSRDVAEDKDFSITCSAS--G 62

Query: 2405 DPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             P   V W      +  +S     H  G  ++++  ++    GVY C+A N +G
Sbjct: 63   RPAPNVTW------VNKTSGSPVAHGTGNATLSLLKIQRHQAGVYQCQAINNVG 110



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 11/110 (10%)

Query: 1831 QRREDVEVAVN-QAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQS 1889
            ++ ++ + A N +AP F   L+    ++E +     C     P PN  V W    K   S
Sbjct: 22   EKFDEPKTAKNTKAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPN--VTWV--NKTSGS 77

Query: 1890 GHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQ 1937
               + T N    A L +L +    +G Y C+AINN+G+      I +NVQ
Sbjct: 78   PVAHGTGN----ATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITINVQ 123



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 17/139 (12%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G   L +L  +   +G Y C+A N  G+  I+  +        Q P   T IQN   ++ 
Sbjct: 84   GNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITI----NVQYPPEITPIQNTT-VRA 138

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G++    C V    +P   + W   G    HST        G  V   A     D+G+YV
Sbjct: 139  GETITLTCAV--AGNPTPSVSWSKAGS--GHST--------GGNVFTRAGATKADTGQYV 186

Query: 3224 CRAYNKYGEDFTRATINCY 3242
            C A N    +    T + Y
Sbjct: 187  CTAVNTVTGNTQTKTASTY 205



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 15/101 (14%)

Query: 1708 TQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR--NGVPIEASNRLTTMHD 1764
            T+AP F  P+   R VAE++   F       G P   V W+   +G P+         H 
Sbjct: 33   TKAPAFNQPLDRSRDVAEDK--DFSITCSASGRPAPNVTWVNKTSGSPVA--------HG 82

Query: 1765 FGYVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQ 1803
             G   L++  +    +G Y C+AIN +G  A+T   T+ VQ
Sbjct: 83   TGNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITINVQ 123



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 43/187 (22%), Positives = 67/187 (35%), Gaps = 26/187 (13%)

Query: 4406 KPSKPPIFTKKMQPCR-VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            K +K P F + +   R V E +         G P P + W  +      SP       +T
Sbjct: 31   KNTKAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPNVTWVNKT---SGSPVAHGTGNAT 87

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
             S+L I++     + V+   A N  G    + ++ +  +         PP  T   QN  
Sbjct: 88   LSLLKIQR---HQAGVYQCQAINNVGRGAITQDITINVQ--------YPPEIT-PIQNTT 135

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V +G+ + L   V G     V W K G               G        A   D+G+Y
Sbjct: 136  VRAGETITLTCAVAGNPTPSVSWSKAGSG----------HSTGGNVFTRAGATKADTGQY 185

Query: 4585 ECVAINS 4591
             C A+N+
Sbjct: 186  VCTAVNT 192



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 11/122 (9%)

Query: 2616 WEQIQLKEAAMNKVPEMFVDTGVQQ---APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP 2672
            +E I    A+    PE F +    +   AP F   L     + E +   +      R  P
Sbjct: 7    YELITRTTASSEPFPEKFDEPKTAKNTKAPAFNQPLDRSRDVAEDKDFSITCSASGRPAP 66

Query: 2673 NLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
            N  + W    V  T+G+ +      G  TLS+  ++   +G+Y C+A N +G    T  I
Sbjct: 67   N--VTW----VNKTSGSPV--AHGTGNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDI 118

Query: 2733 KI 2734
             I
Sbjct: 119  TI 120



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 9/106 (8%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P F QPL     V+E K+  + C     G P   V W +     T GS     +  G   
Sbjct: 36   PAFNQPLDRSRDVAEDKDFSITC--SASGRPAPNVTWVNK----TSGS--PVAHGTGNAT 87

Query: 1237 LDIIHATSADTGEYTVRAVNHLG-SAHTSAIVRVIERSDIVTDTQN 1281
            L ++       G Y  +A+N++G  A T  I   ++    +T  QN
Sbjct: 88   LSLLKIQRHQAGVYQCQAINNVGRGAITQDITINVQYPPEITPIQN 133



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 38/134 (28%), Positives = 55/134 (41%), Gaps = 15/134 (11%)

Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEAT 2000
            S+++  +H++ + + Q + +  R     QD +  V+ P    PI+N  V  G  + L  T
Sbjct: 89   SLLKIQRHQAGVYQCQAINNVGR-GAITQDITINVQYPPEITPIQNTTVRAGETITL--T 145

Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV-G 2059
                 +PT  V W   G     GH        G        A   DTG Y+C A N V G
Sbjct: 146  CAVAGNPTPSVSWSKAG----SGH------STGGNVFTRAGATKADTGQYVCTAVNTVTG 195

Query: 2060 EAVT-TSSVKVDAK 2072
               T T+S  V  K
Sbjct: 196  NTQTKTASTYVMVK 209



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 12/100 (12%)

Query: 904  ESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLK--DGRPVEASSRITTF 961
            ++T+ P F  P+     + E     F       G     V W+    G PV   +     
Sbjct: 31   KNTKAPAFNQPLDRSRDVAED--KDFSITCSASGRPAPNVTWVNKTSGSPVAHGT----- 83

Query: 962  FNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
               G   L++  +  H AG Y C+A N +G+   + ++TI
Sbjct: 84   ---GNATLSLLKIQRHQAGVYQCQAINNVGRGAITQDITI 120


>SB_30290| Best HMM Match : I-set (HMM E-Value=1.4e-21)
          Length = 250

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 54/188 (28%), Positives = 76/188 (40%), Gaps = 23/188 (12%)

Query: 390 LAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           +AP F   +   RDV E       C  +GRP P VTW +N        +   + + +G+ 
Sbjct: 74  VAPAFTSSLSSSRDVAENGDVTVTCSASGRPAPNVTW-VNKT------SGSPVAHGTGSA 126

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508
            L +  +    +GV  C A N  G  A    + +     V  P  +       VR GE +
Sbjct: 127 TLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTI----NVQYPPEITPIQNTTVRAGETI 182

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN- 567
            L     G PTP ++W K G           H+ GG +      A  +D   Y CTA N 
Sbjct: 183 TLTCAVAGNPTPSVSWSKTGSG---------HSTGG-NVFTKAGATKADTGQYVCTAVNT 232

Query: 568 VAGSTATR 575
           V G+T TR
Sbjct: 233 VTGNTQTR 240



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 39/172 (22%), Positives = 65/172 (37%), Gaps = 21/172 (12%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            VAE   +  +C   G+P P V W      +  +    ++      TL + +      G Y
Sbjct: 88   VAENGDVTVTCSASGRPAPNVTW------VNKTSGSPVAHGTGSATLSLLKIQRHQAGVY 141

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
            +C A N  GRV +   + +         P +TP+++  V  G+       +     P++ 
Sbjct: 142  QCQAINDVGRVAITQDVTIN----VQYPPEITPIQNTTVRAGETITLTCAVAGNPTPSVS 197

Query: 4754 WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA-TTAAGQVET 4804
            W + G+             G N     G T + DTG + C A  T  G  +T
Sbjct: 198  WSKTGS---------GHSTGGNVFTKAGAT-KADTGQYVCTAVNTVTGNTQT 239



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 22/148 (14%)

Query: 4512 VPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            V P+FT + + + +V     V +    +G    +V W+ N     P     +    G+ T
Sbjct: 74   VAPAFTSSLSSSRDVAENGDVTVTCSASGRPAPNVTWV-NKTSGSP-----VAHGTGSAT 127

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L +L+     +G Y+C AIN  G      +  +++                PPEI  P++
Sbjct: 128  LSLLKIQRHQAGVYQCQAINDVGRVAITQDVTINV--------------QYPPEIT-PIQ 172

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            +  V  G+ I  +C + G P P+V W K
Sbjct: 173  NTTVRAGETITLTCAVAGNPTPSVSWSK 200



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 8/116 (6%)

Query: 2619 IQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEW 2678
            ++++ ++    P    +  ++ AP FT+ L S   + E   V +      R  PN  + W
Sbjct: 53   VKIRTSSSPLSPSASWELNIKVAPAFTSSLSSSRDVAENGDVTVTCSASGRPAPN--VTW 110

Query: 2679 FKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                V  T+G+ +      G  TLS+  ++   +G+Y C+A N +G    T  + I
Sbjct: 111  ----VNKTSGSPV--AHGTGSATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTI 160



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            E+ +  AP F + L+    ++E       C     P PN  V W    K   S   + T 
Sbjct: 69   ELNIKVAPAFTSSLSSSRDVAENGDVTVTCSASGRPAPN--VTWV--NKTSGSPVAHGT- 123

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQ 1937
               G A L +L +    +G Y C+AIN++G+      + +NVQ
Sbjct: 124  ---GSATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTINVQ 163



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 12/98 (12%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRPFATGSRVHTLNDFGF 3752
            P FT  +  + DV E G V   C     G P   + W +  +G P A G+        G 
Sbjct: 76   PAFTSSLSSSRDVAENGDVTVTCSAS--GRPAPNVTWVNKTSGSPVAHGT--------GS 125

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L +  I    AG Y C+A N  G    T  +T + +
Sbjct: 126  ATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTINVQ 163



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 15/134 (11%)

Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEAT 2000
            S+++  +H++ + + Q + D  R     QD +  V+ P    PI+N  V  G  + L  T
Sbjct: 129  SLLKIQRHQAGVYQCQAINDVGRVA-ITQDVTINVQYPPEITPIQNTTVRAGETITL--T 185

Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV-G 2059
                 +PT  V W   G     GH        G        A   DTG Y+C A N V G
Sbjct: 186  CAVAGNPTPSVSWSKTG----SGH------STGGNVFTKAGATKADTGQYVCTAVNTVTG 235

Query: 2060 EAVT-TSSVKVDAK 2072
               T T+S  V  K
Sbjct: 236  NTQTRTASTYVIVK 249



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 17/139 (12%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G   L +L  +   +G Y C+A N  G+  I+  +        Q P   T IQN   ++ 
Sbjct: 124  GSATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTI----NVQYPPEITPIQNTT-VRA 178

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G++    C V    +P   + W   G    HST        G  V   A     D+G+YV
Sbjct: 179  GETITLTCAV--AGNPTPSVSWSKTGS--GHST--------GGNVFTKAGATKADTGQYV 226

Query: 3224 CRAYNKYGEDFTRATINCY 3242
            C A N    +    T + Y
Sbjct: 227  CTAVNTVTGNTQTRTASTY 245



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 14/119 (11%)

Query: 1807 SLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYEC 1866
            SL    +H++ + + Q + D  R    +DV + V Q P  IT +   T +  G++    C
Sbjct: 129  SLLKIQRHQAGVYQCQAINDVGRVAITQDVTINV-QYPPEITPIQN-TTVRAGETITLTC 186

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
             +   P P+  V W   G    SGH     N F  A          D+G+Y C A+N +
Sbjct: 187  AVAGNPTPS--VSWSKTG----SGHS-TGGNVFTKAG-----ATKADTGQYVCTAVNTV 233



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 42/182 (23%), Positives = 64/182 (35%), Gaps = 26/182 (14%)

Query: 4411 PIFTKKMQPCR-VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P FT  +   R V E+          G P P + W  +      SP       +T S+L 
Sbjct: 76   PAFTSSLSSSRDVAENGDVTVTCSASGRPAPNVTWVNKT---SGSPVAHGTGSATLSLLK 132

Query: 4470 IRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQ 4529
            I++     + V+   A N  G    + ++ +  +         PP  T   QN  V +G+
Sbjct: 133  IQR---HQAGVYQCQAINDVGRVAITQDVTINVQ--------YPPEIT-PIQNTTVRAGE 180

Query: 4530 LVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
             + L   V G     V W K G               G        A   D+G+Y C A+
Sbjct: 181  TITLTCAVAGNPTPSVSWSKTGSG----------HSTGGNVFTKAGATKADTGQYVCTAV 230

Query: 4590 NS 4591
            N+
Sbjct: 231  NT 232



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 32/122 (26%), Positives = 51/122 (41%), Gaps = 21/122 (17%)

Query: 1304 DITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGDQTMRVEWF--CNGKPIKTGHRFR 1360
            ++ +  AP F+ +L +   V E  +V + C     G     V W    +G P+       
Sbjct: 69   ELNIKVAPAFTSSLSSSRDVAENGDVTVTCSAS--GRPAPNVTWVNKTSGSPV------- 119

Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK 1420
             A+      L LL +    +GVY CQA N +G        RV   +D+ +  Q+P  +  
Sbjct: 120  -AHGTGSATLSLLKIQRHQAGVYQCQAINDVG--------RVAITQDVTINVQYPPEITP 170

Query: 1421 IQ 1422
            IQ
Sbjct: 171  IQ 172



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 15/102 (14%)

Query: 1707 ITQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR--NGVPIEASNRLTTMH 1763
            I  AP FT  +   R VAEN            G P   V W+   +G P+         H
Sbjct: 72   IKVAPAFTSSLSSSRDVAEN--GDVTVTCSASGRPAPNVTWVNKTSGSPVA--------H 121

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQ 1803
              G   L++  +    +G Y C+AIN++G  A+T   T+ VQ
Sbjct: 122  GTGSATLSLLKIQRHQAGVYQCQAINDVGRVAITQDVTINVQ 163



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/85 (31%), Positives = 35/85 (41%), Gaps = 13/85 (15%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I+   P  + P+ N   V  G+ I L C +   G+PT  V W   G   + G    T   
Sbjct: 160  INVQYPPEITPIQNTT-VRAGETITLTCAVA--GNPTPSVSWSKTGSGHSTGGNVFTKAG 216

Query: 1232 FGFVALDIIHATSADTGEYTVRAVN 1256
                      AT ADTG+Y   AVN
Sbjct: 217  ----------ATKADTGQYVCTAVN 231


>SB_24384| Best HMM Match : I-set (HMM E-Value=4.3e-31)
          Length = 1399

 Score = 66.5 bits (155), Expect = 5e-10
 Identities = 64/217 (29%), Positives = 86/217 (39%), Gaps = 28/217 (12%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKN--GKKVQPDIRN---KILEED 4566
            PP FT+T +N N T  +  +L   V       V  W     G  V   +     K     
Sbjct: 537  PPQFTMTPRNSNATLNRTTQLHCAVASANLRTVITWHMRPVGSSVLTPVDTLDPKRFLVL 596

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
               TL+I      D   Y C A N  G    +A   + +P + D               +
Sbjct: 597  ANMTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIFVPPSFD---------------V 641

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY-KGDKLIKPSKYFQMSRTADEYTLRISEA 4685
             P KD  V +G +    CK VG P PT+ WY KG K     K+F++  +   Y   I E 
Sbjct: 642  LP-KDLEVPQGGSPTLQCKGVGDPRPTITWYRKGSKTFP--KHFKVRPSGSLY---IREI 695

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLP 4722
              ED+G Y C A NS G  T    +KV    + DN+P
Sbjct: 696  TKEDQGTYVCQADNSVGTATAQVIIKVFTACRIDNIP 732



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 71/288 (24%), Positives = 111/288 (38%), Gaps = 37/288 (12%)

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILE--EDGTYTLLILEAYPQDSGKYECVAIN 4590
            +D KV       V+W K+        +   LE  E    +L +  A    +G+Y C A N
Sbjct: 462  IDCKVIADPRAKVFWTKSRPWPNEQGQLSRLEFLEFSNGSLYVRRARMSYTGQYYCTAAN 521

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP 4650
            SA       E  V                 APP+     ++      +  +  C +    
Sbjct: 522  SAAFDIGSFEIKVG----------------APPQFTMTPRNSNATLNRTTQLHCAVASAN 565

Query: 4651 LPTV-QWYK---GDKLIKPSKYFQMSR--TADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            L TV  W+    G  ++ P       R       TL I      DE  Y C A N  G  
Sbjct: 566  LRTVITWHMRPVGSSVLTPVDTLDPKRFLVLANMTLMIKNLKKSDEAAYVCTANNPVGTK 625

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGA-LIPE 4763
            +  A LK+  P   D LP     +D+ V +G     + +     +PTI W R+G+   P+
Sbjct: 626  SSEAFLKIFVPPSFDVLP-----KDLEVPQGGSPTLQCKGVGDPRPTITWYRKGSKTFPK 680

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
               F++   G+   L I    +ED GT+ C+A  + G    +A++++K
Sbjct: 681  --HFKVRPSGS---LYIREITKEDQGTYVCQADNSVG--TATAQVIIK 721



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 52/189 (27%), Positives = 70/189 (37%), Gaps = 17/189 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEV-TWFINDRQIR-----DDYNHKILVNES 445
           PQF    ++ + T  + T+  C V       V TW +           D  + K  +   
Sbjct: 538 PQFTMTPRNSNATLNRTTQLHCAVASANLRTVITWHMRPVGSSVLTPVDTLDPKRFL-VL 596

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
            N  LMI N+  SD     C A N  G  + +  L +      V P F      L V +G
Sbjct: 597 ANMTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIF-----VPPSFDVLPKDLEVPQG 651

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
               L  + VG P P ITW + G    P    ++   G   +L I      D   Y C A
Sbjct: 652 GSPTLQCKGVGDPRPTITWYRKGSKTFPK-HFKVRPSG---SLYIREITKEDQGTYVCQA 707

Query: 566 QNVAGSTAT 574
            N  G TAT
Sbjct: 708 DNSVG-TAT 715



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 54/253 (21%), Positives = 95/253 (37%), Gaps = 6/253 (2%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           K+  +P   V WT+ +    E  + S     +  + SL +++      G+Y CTA N   
Sbjct: 465 KVIADPRAKVFWTKSRPWPNEQGQLSRLEFLEFSNGSLYVRRARMSYTGQYYCTAANSAA 524

Query: 154 EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQGYTTEQSRQTQKVAYTNGT 213
             I S  I+  G                   T  H A  +    T  +   + V  +  T
Sbjct: 525 FDIGSFEIKV-GAPPQFTMTPRNSNATLNRTTQLHCAVASANLRTVITWHMRPVGSSVLT 583

Query: 214 DHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQISTEIDRSLGPVS-PPKIAQKP 272
              + D  +        L   + ++S    YV  ++  + T+   +   +  PP     P
Sbjct: 584 PVDTLDPKRFLVLANMTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIFVPPSFDVLP 643

Query: 273 RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSD 332
           ++ ++ +G     Q +  G+PRP +TW++ G +     KH         +L +R   K D
Sbjct: 644 KDLEVPQGGSPTLQCKGVGDPRPTITWYRKGSKTF--PKH--FKVRPSGSLYIREITKED 699

Query: 333 SGHYTLLAENPNG 345
            G Y   A+N  G
Sbjct: 700 QGTYVCQADNSVG 712



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 6/92 (6%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP F+ + K+    QGG+   + K  G+P P ++W RK       +K   ++ +     S
Sbjct: 636 PPSFDVLPKDLEVPQGGSPTLQCKGVGDPRPTITWYRKG------SKTFPKHFKVRPSGS 689

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           L I++I   D+G Y C A N  G A   V I+
Sbjct: 690 LYIREITKEDQGTYVCQADNSVGTATAQVIIK 721



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFI 3753
            PP F V  KD ++VP+GG     C+   VGDP   I W+  G    T  +   +   G  
Sbjct: 636  PPSFDVLPKD-LEVPQGGSPTLQCK--GVGDPRPTITWYRKGSK--TFPKHFKVRPSG-- 688

Query: 3754 ALDIDYIYARDAGEYTCRATNKWGSAT 3780
            +L I  I   D G Y C+A N  G+AT
Sbjct: 689  SLYIREITKEDQGTYVCQADNSVGTAT 715



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 14/128 (10%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L+I+ +   D A +   A N  GT    A L +           VPPSF +  +++ V  
Sbjct: 601  LMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKI----------FVPPSFDVLPKDLEVPQ 650

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G    L  K  G     + W + G K  P    K  +   + +L I E   +D G Y C 
Sbjct: 651  GGSPTLQCKGVGDPRPTITWYRKGSKTFP----KHFKVRPSGSLYIREITKEDQGTYVCQ 706

Query: 4588 AINSAGEA 4595
            A NS G A
Sbjct: 707  ADNSVGTA 714



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 8/106 (7%)

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            TK     + +   P F     ++E  +G +  L+C+   VGD    + W+  G      H
Sbjct: 624  TKSSEAFLKIFVPPSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKH 681

Query: 1358 -RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             + RP+      +L +  +  ED G Y CQA N +G A     ++V
Sbjct: 682  FKVRPSG-----SLYIREITKEDQGTYVCQADNSVGTATAQVIIKV 722



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 10/120 (8%)

Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRF 691
           +++ PP F V  K +   +GG    + +   VGDP   I W + G     S  F   F+ 
Sbjct: 632 KIFVPPSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKG-----SKTFPKHFKV 684

Query: 692 GYI-SLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERT--SQHPETLQYIQ 748
               SL +  +  +D G Y C+A ++ G A  + ++ V     I+      H   LQ+ +
Sbjct: 685 RPSGSLYIREITKEDQGTYVCQADNSVGTATAQVIIKVFTACRIDNIPFGSHEPKLQFFR 744



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 5/91 (5%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P F  + +D +V +G      C+  G P P +TW+   R+    +     V  SG+  L 
Sbjct: 637 PSFDVLPKDLEVPQGGSPTLQCKGVGDPRPTITWY---RKGSKTFPKHFKVRPSGS--LY 691

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           I  +T  D G   C A N  G    Q  + V
Sbjct: 692 IREITKEDQGTYVCQADNSVGTATAQVIIKV 722



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 6/92 (6%)

Query: 1978 PQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVAL 2037
            P F    K+ EV +G    L+     V DP   + WY  G      H FK          
Sbjct: 637  PSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKH-FKVRPSGSLYIR 693

Query: 2038 DILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +I     ED GTY+C+A N+VG A     +KV
Sbjct: 694  EIT---KEDQGTYVCQADNSVGTATAQVIIKV 722



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 39/152 (25%), Positives = 66/152 (43%), Gaps = 11/152 (7%)

Query: 3502 GEAVTTASMKVQGKRNIILESQ--LPKGMEGTIDKIAALEGYSGTVDTLTPEA--ESGNP 3557
            G +V T    +  KR ++L +   + K ++ + D+ A +   +  V T + EA  +   P
Sbjct: 578  GSSVLTPVDTLDPKRFLVLANMTLMIKNLKKS-DEAAYVCTANNPVGTKSSEAFLKIFVP 636

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F   P DL + +  S   +C+   V D    + W+  G    T  +   +   G   L
Sbjct: 637  PSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGSK--TFPKHFKVRPSGS--L 690

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
             I  + + D G Y C+A N  G AT    ++V
Sbjct: 691  YIREITKEDQGTYVCQADNSVGTATAQVIIKV 722



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 7/88 (7%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF 1499
            + + P F   PK +E V +G     +CK   V D    + W++ G   T    F+ +   
Sbjct: 633  IFVPPSFDVLPKDLE-VPQGGSPTLQCK--GVGDPRPTITWYRKGSK-TFPKHFK-VRPS 687

Query: 1500 GYVALDIIDLIAEDSGIYTCRAVNLVGT 1527
            G  +L I ++  ED G Y C+A N VGT
Sbjct: 688  G--SLYIREITKEDQGTYVCQADNSVGT 713



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 2123 EGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTY 2182
            +G     +C+   + DP  TI W+  G K    H ++          +I     ED GTY
Sbjct: 650  QGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKH-FKVRPSGSLYIREIT---KEDQGTY 703

Query: 2183 MCKATNKLGEAVNTCTLKV 2201
            +C+A N +G A     +KV
Sbjct: 704  VCQADNSVGTATAQVIIKV 722



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 9/126 (7%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNG-KTIEASHRIRTVYAFGM 3105
            PP F  + KD+ ++ +G     +   +  GD    I W+  G KT     ++R   +  +
Sbjct: 636  PPSFDVLPKDL-EVPQGGSPTLQCKGV--GDPRPTITWYRKGSKTFPKHFKVRP--SGSL 690

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
             + EI  TK  D GTY C+A N  G A   V ++     +     F +H   ++  + G 
Sbjct: 691  YIREI--TKE-DQGTYVCQADNSVGTATAQVIIKVFTACRIDNIPFGSHEPKLQFFRVGS 747

Query: 3166 SAHFEC 3171
                +C
Sbjct: 748  VVQVQC 753



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 6/84 (7%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P F +  KD+ V +  +   + +   VGDP+  + W R G   +   +   +   G  +L
Sbjct: 637  PSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGS--KTFPKHFKVRPSG--SL 690

Query: 1771 NMKYVNPEDSGTYTCRAINELGEA 1794
             ++ +  ED GTY C+A N +G A
Sbjct: 691  YIREITKEDQGTYVCQADNSVGTA 714



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 8/87 (9%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG-KLLPSGHRYRTVYDM 3884
            +  PP F    K   V +      +C+     DP+  I WYR G K  P   + R     
Sbjct: 633  IFVPPSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKHFKVRP---S 687

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911
            G  SL I  +  ED G Y+C+A N  G
Sbjct: 688  G--SLYIREITKEDQGTYVCQADNSVG 712



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 8/102 (7%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQL-SGNPRPRVTWFKN--GQRLINS----NKHEIIT 316
           +PP+    PRNS        Q    + S N R  +TW     G  ++      +    + 
Sbjct: 536 APPQFTMTPRNSNATLNRTTQLHCAVASANLRTVITWHMRPVGSSVLTPVDTLDPKRFLV 595

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
             N  TL ++N +KSD   Y   A NP G   +  +L +  P
Sbjct: 596 LAN-MTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIFVP 636



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 10/96 (10%)

Query: 1178 VFVQPLSNPPP----VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFG 1233
            +FV P  +  P    V +G +  L+C+   +GDP   + W+  G S T    FK      
Sbjct: 633  IFVPPSFDVLPKDLEVPQGGSPTLQCK--GVGDPRPTITWYRKG-SKTFPKHFKVRPSGS 689

Query: 1234 FVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRV 1269
                +I   T  D G Y  +A N +G+A    I++V
Sbjct: 690  LYIREI---TKEDQGTYVCQADNSVGTATAQVIIKV 722



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 6/84 (7%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIH-TFSTKSIL 4468
            PP F    +   V +      + +  G+P P I WYR     K S  F  H        L
Sbjct: 636  PPSFDVLPKDLEVPQGGSPTLQCKGVGDPRPTITWYR-----KGSKTFPKHFKVRPSGSL 690

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTA 4492
             IR++  ED   +   A+N  GTA
Sbjct: 691  YIREITKEDQGTYVCQADNSVGTA 714



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 6/71 (8%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + +G +    C+   VGDP   + W+R  K  +   +  K    G  S+ I  +  ED+G
Sbjct: 648  VPQGGSPTLQCK--GVGDPRPTITWYR--KGSKTFPKHFKVRPSG--SLYIREITKEDQG 701

Query: 2448 VYMCRASNLLG 2458
             Y+C+A N +G
Sbjct: 702  TYVCQADNSVG 712



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 9/96 (9%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV- 967
            P F    KD + + +GG    + +   +GD    + W + G     S      F      
Sbjct: 637  PSFDVLPKD-LEVPQGGSPTLQCK--GVGDPRPTITWYRKG-----SKTFPKHFKVRPSG 688

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003
            +L I+ +T  D G Y C+A N++G AT    + + T
Sbjct: 689  SLYIREITKEDQGTYVCQADNSVGTATAQVIIKVFT 724



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYRTSNDFGFAALDILTVYGED 1913
            ++ +G S   +C+     DP   + WY  G K      + R S      +L I  +  ED
Sbjct: 647  EVPQGGSPTLQCK--GVGDPRPTITWYRKGSKTFPKHFKVRPSG-----SLYIREITKED 699

Query: 1914 SGEYTCKAINNLGQAVSSIRLNV 1936
             G Y C+A N++G A + + + V
Sbjct: 700  QGTYVCQADNSVGTATAQVIIKV 722



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 19/155 (12%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DP   + WY  G S      F+        I EI+    ED G Y+C+A N+ G A    
Sbjct: 663  DPRPTITWYRKG-SKTFPKHFKVRPSGSLYIREITK---EDQGTYVCQADNSVGTATAQV 718

Query: 3509 SMKVQGK---RNIILESQLPK---GMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFT- 3561
             +KV       NI   S  PK      G++ ++    GYS T +  T     G+  EF  
Sbjct: 719  IIKVFTACRIDNIPFGSHEPKLQFFRVGSVVQVQCYPGYS-TSEGPTTNLTCGDDGEFNE 777

Query: 3562 TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN 3596
            + P    L        ECR+ P + +   V+ +H+
Sbjct: 778  SMPKCKDLD-------ECRVSPSSVNDHDVKTYHD 805



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 34/137 (24%), Positives = 47/137 (34%), Gaps = 12/137 (8%)

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            + L I   K +D   Y C A N  G       L+         P F    +++E +  G 
Sbjct: 599  MTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKIF-----VPPSFDVLPKDLE-VPQGG 652

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            S   +C    V DP   I WY  G         K        + +I      D G YVC+
Sbjct: 653  SPTLQCK--GVGDPRPTITWYRKGSKT-FPKHFKVRPSGSLYIREIT---KEDQGTYVCQ 706

Query: 3226 AYNKYGEDFTRATINCY 3242
            A N  G    +  I  +
Sbjct: 707  ADNSVGTATAQVIIKVF 723



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 10/115 (8%)

Query: 3542 SGTVDTLTPEAESGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHN--GKP 3599
            S   D  + E + G PP+FT TP +   + N +    C +   N  ++ + W     G  
Sbjct: 522  SAAFDIGSFEIKVGAPPQFTMTPRNSNATLNRTTQLHCAVASANLRTV-ITWHMRPVGSS 580

Query: 3600 LLTGSRVKTINDFGFVILE-----IGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +LT   V T++   F++L      I  + + D   Y C A N  G  +    L++
Sbjct: 581  VLT--PVDTLDPKRFLVLANMTLMIKNLKKSDEAAYVCTANNPVGTKSSEAFLKI 633


>SB_14894| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1052

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 82/323 (25%), Positives = 119/323 (36%), Gaps = 35/323 (10%)

Query: 4508 RGGIVPPSFTLTAQN-VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEED 4566
            R  +  P FT   ++   V  G+  RL  + +G  P   YWLKNG  V P  R +I++  
Sbjct: 243  RPSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRIVKN- 301

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
              Y L I      D+G+Y CV  N+ GE        V  P          +A  A P   
Sbjct: 302  -RY-LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMKRAFIAWPA-- 357

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF 4686
                        ++   C+  G P     W K  K IK  +      T   +  R+ +  
Sbjct: 358  ----------SHSMRLRCQATGTPPLRYHWLKDGKEIKGRRLDPYMNTT-LWFFRLKDLV 406

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKV-----TQPDQADNLPALTPLR--------DIVVY 4733
            P D G Y C+  N+ G +     L+V     ++P    NLP  T +          IVV 
Sbjct: 407  PTDTGKYTCIVSNAYGSINHTYTLRVIAKPRSRPILQRNLPRNTSIELGGNATLDCIVVV 466

Query: 4734 EGQPAQFKTQITSKIKPTIQWL--REGALIPETPDFQMIHEGNNAV---LLIGNTYEEDT 4788
             G    F+     K+  T   L    G+     P +    E        L + N  ++D 
Sbjct: 467  SGTLPDFRWLKWDKVPSTYPELDLNNGSYTLIDPVYYRTIEAGETYGVQLTVVNVTKKDL 526

Query: 4789 GTFTCRATTAAGQVETSAKLVVK 4811
            G +TC  +   G+   SA L  K
Sbjct: 527  GLYTCYVSNHIGKDYVSAFLSEK 549



 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 68/278 (24%), Positives = 112/278 (40%), Gaps = 24/278 (8%)

Query: 4405 VKPS-KPPIFTKKMQPC-RVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTF 4462
            ++PS   P FTK ++   +V   E AR +    G P P   W +   P+   P  +I   
Sbjct: 242  LRPSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVV--PSHRIRIV 299

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
              +  L I+   + D+  +  V  N  G    S +L V+E  R      +  +F      
Sbjct: 300  KNR-YLKIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMKRAF------ 352

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            +   +   +RL  + TGT P+  +WLK+GK+++    +  +     +   + +  P D+G
Sbjct: 353  IAWPASHSMRLRCQATGTPPLRYHWLKDGKEIKGRRLDPYMNTT-LWFFRLKDLVPTDTG 411

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
            KY C+  N+ G         V +   + +P  Q            P    I   G A   
Sbjct: 412  KYTCIVSNAYGSINHTYTLRV-IAKPRSRPILQRNL---------PRNTSIELGGNATLD 461

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
               +V   LP  +W K DK+  PS Y ++      YTL
Sbjct: 462  CIVVVSGTLPDFRWLKWDKV--PSTYPELDLNNGSYTL 497



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 48/181 (26%), Positives = 72/181 (39%), Gaps = 7/181 (3%)

Query: 392 PQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           P+F K  +    V  G+  R  CR +G P P   W  N   +    +H+I + +  N  L
Sbjct: 249 PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVP--SHRIRIVK--NRYL 304

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
            I +  L D+G   CV  N  GE      L+V E  + +    ++R + +       + L
Sbjct: 305 KIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMKR-AFIAWPASHSMRL 363

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             +A GTP  R  W KDG   I    L  + +       +     +D   Y C   N  G
Sbjct: 364 RCQATGTPPLRYHWLKDGKE-IKGRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422

Query: 571 S 571
           S
Sbjct: 423 S 423



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 28/97 (28%), Positives = 52/97 (53%), Gaps = 4/97 (4%)

Query: 263 VSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           +S PK  +  ++S +++ G  A+ + + SG P P   W KNG  ++ S++  I+    + 
Sbjct: 246 LSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRIV---KNR 302

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
            L++++T   D+G Y  +  N  G I  S +L V+ P
Sbjct: 303 YLKIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEP 339



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 3148 KPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFV 3207
            +P+FT  +++   +K G+SA  +C    V  P     W  NG P+  S RI+ V +    
Sbjct: 248  QPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKNR--- 302

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGE 3232
             L I  T   D+GEY+C   N YGE
Sbjct: 303  YLKIKSTVLGDAGEYICVFNNTYGE 327



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 33/97 (34%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            S  +P+F   +K    +K G  A  + R    G       WLK+G PV  S RI    N 
Sbjct: 245  SLSQPKFTKAVKSSYQVKLGESARLKCRAS--GVPPPYSYWLKNGLPVVPSHRIRIVKN- 301

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
             Y  L IKS  + DAG Y C   N  G+   S +L +
Sbjct: 302  RY--LKIKSTVLGDAGEYICVFNNTYGEINASIHLDV 336



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 27/76 (35%), Positives = 34/76 (44%), Gaps = 1/76 (1%)

Query: 1330 LECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN 1389
            +  R Q  G   +R  W  +GK IK G R  P          L  + P D+G YTC  +N
Sbjct: 361  MRLRCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSN 419

Query: 1390 QLGEAVTSCALRVIAK 1405
              G    +  LRVIAK
Sbjct: 420  AYGSINHTYTLRVIAK 435



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 59/235 (25%), Positives = 94/235 (40%), Gaps = 30/235 (12%)

Query: 3443 RLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYG 3502
            R   T  P L+  W  +GK +K G R   + +       +    P D+G+Y C   N YG
Sbjct: 364  RCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422

Query: 3503 EAVTTASMKVQGK--RNIILESQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEF 3560
                T +++V  K     IL+  LP+     +       G + T+D +     SG  P+F
Sbjct: 423  SINHTYTLRVIAKPRSRPILQRNLPRNTSIEL-------GGNATLDCIV--VVSGTLPDF 473

Query: 3561 TTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIG 3620
                 D + S           + +N+ S  +       P+   + ++    +G V L + 
Sbjct: 474  RWLKWDKVPSTYPE-------LDLNNGSYTLI-----DPVYYRT-IEAGETYG-VQLTVV 519

Query: 3621 GVYQRDAGLYTCKATNRHGEATVSCKLQVK----GRQGIILEPQLPSHFKSGTES 3671
             V ++D GLYTC  +N  G+  VS  L  K      + +IL P   S     T S
Sbjct: 520  NVTKKDLGLYTCYVSNHIGKDYVSAFLSEKIIPTTTRPVILVPTKKSKLNVNTSS 574



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 45/187 (24%), Positives = 72/187 (38%), Gaps = 16/187 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P+FT   K    +  G+ A  +     +G       W  NG  +  SHRIR V       
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRA--SGVPPPYSYWLKNGLPVVPSHRIRIVKNR---Y 303

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L+I  T   D+G Y C   N +G+   S+ L+       + PRF    +         ++
Sbjct: 304  LKIKSTVLGDAGEYICVFNNTYGEINASIHLDV-----KEPPRFLDWNKMKRAFIAWPAS 358

Query: 3168 H-FECTVVPVDDPDMKIEWYHNGQPM--RHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            H           P ++  W  +G+ +  R        + + F + D+  T   D+G+Y C
Sbjct: 359  HSMRLRCQATGTPPLRYHWLKDGKEIKGRRLDPYMNTTLWFFRLKDLVPT---DTGKYTC 415

Query: 3225 RAYNKYG 3231
               N YG
Sbjct: 416  IVSNAYG 422



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 33/107 (30%), Positives = 47/107 (43%), Gaps = 6/107 (5%)

Query: 3830 PKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PKF   +KS + V+  E  R +CR      P     W +NG  +   HR R V +     
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKNR---Y 303

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
            L I      D+GEYIC   N +GE      +  K+ P  +  N++ R
Sbjct: 304  LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMKR 350



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 26/97 (26%), Positives = 42/97 (43%), Gaps = 5/97 (5%)

Query: 65  RPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
           RP    P   + +  + +   G +A+ + +  G P P   W +   P+V  ++  +  N 
Sbjct: 243 RPSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRIVKNR 302

Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
                 L IK    GD GEY C   N YGE   S+++
Sbjct: 303 Y-----LKIKSTVLGDAGEYICVFNNTYGEINASIHL 334



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 42/193 (21%), Positives = 77/193 (39%), Gaps = 8/193 (4%)

Query: 4623 PEIIEPLKDKI-VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P+  + +K    V  G++    C+  G P P   W K    + PS   ++ +  + Y L+
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRIVK--NRY-LK 305

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA-QF 4740
            I      D G+Y CV  N+ G +  +  L V +P +  +   +   R  + +    + + 
Sbjct: 306  IKSTVLGDAGEYICVFNNTYGEINASIHLDVKEPPRFLDWNKMK--RAFIAWPASHSMRL 363

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + Q T        WL++G  I +                + +    DTG +TC  + A G
Sbjct: 364  RCQATGTPPLRYHWLKDGKEI-KGRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422

Query: 4801 QVETSAKLVVKSK 4813
             +  +  L V +K
Sbjct: 423  SINHTYTLRVIAK 435



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 1/73 (1%)

Query: 932  RLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIG 991
            R +  G   LR  WLKDG+ ++   R+  + N       +K +   D G YTC   NA G
Sbjct: 364  RCQATGTPPLRYHWLKDGKEIKGR-RLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422

Query: 992  QATTSANLTIVTK 1004
                +  L ++ K
Sbjct: 423  SINHTYTLRVIAK 435



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 5/94 (5%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P+F   +    ++  G+SA  +CR    P P     W  NG  +   HR R   +     
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN---RY 303

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            L I +    D+GEY C   N  G+  +SI L+V+
Sbjct: 304  LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVK 337



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETT---KFECQLAPVGDPNMKVEWFFNGKPLLHKNRFT 4023
            +D K+PPRF+   + + + +    +   +  CQ    G P ++  W  +GK +  + R  
Sbjct: 334  LDVKEPPRFLDWNKMKRAFIAWPASHSMRLRCQAT--GTPPLRYHWLKDGKEIKGR-RLD 390

Query: 4024 PIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTGKP 4069
            P  +          + P D+G+Y C  +N YG       ++   KP
Sbjct: 391  PYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYGSINHTYTLRVIAKP 436



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 5/85 (5%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV 2167
            +P F  A+ S   +K G+ A  +CR   +  P+    W  NG  +   HR R   +  Y 
Sbjct: 248  QPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN-RY- 303

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGE 2192
             L I  T   D+G Y+C   N  GE
Sbjct: 304  -LKIKSTVLGDAGEYICVFNNTYGE 327



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 48/210 (22%), Positives = 81/210 (38%), Gaps = 23/210 (10%)

Query: 3718 RVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWG 3777
            R +  G P +R  W  +G+    G R+    +       +  +   D G+YTC  +N +G
Sbjct: 364  RCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYG 422

Query: 3778 SA--TTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQ 3835
            S   T T ++    +   +L+  LP+  S      +E G  +       +  T P F   
Sbjct: 423  SINHTYTLRVIAKPRSRPILQRNLPRNTS------IELGGNATLDCIVVVSGTLPDF-RW 475

Query: 3836 IKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVY 3895
            +K   V             P   P+L +       + P  +R     +   V L ++ V 
Sbjct: 476  LKWDKV-------------PSTYPELDLNNGSYTLIDPVYYRTIEAGETYGVQLTVVNVT 522

Query: 3896 AEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
             +D G Y C   N  G+D+  A +S K +P
Sbjct: 523  KKDLGLYTCYVSNHIGKDYVSAFLSEKIIP 552



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 5/83 (6%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P+FT  +K +  V  G      CR   V  P     W  NG P     R+  + +     
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN---RY 303

Query: 3755 LDIDYIYARDAGEYTCRATNKWG 3777
            L I      DAGEY C   N +G
Sbjct: 304  LKIKSTVLGDAGEYICVFNNTYG 326



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 6/94 (6%)

Query: 3558 PEFT-TTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVI 3616
            P+FT    S   +    SA  +CR   V        W  NG P++   R++ + +     
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKNR---Y 303

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            L+I      DAG Y C   N +GE   S  L VK
Sbjct: 304  LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVK 337



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 41/184 (22%), Positives = 74/184 (40%), Gaps = 22/184 (11%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEI 3134
            TG   +   W  +GK I+   R+       +    +     TD+G Y+C  +N +G    
Sbjct: 368  TGTPPLRYHWLKDGKEIKG-RRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYGSINH 426

Query: 3135 SVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDD-PDMK-IEW------- 3185
            +  L  + K +  +P    ++     ++ G +A  +C VV     PD + ++W       
Sbjct: 427  TYTLRVIAKPR-SRPILQRNLPRNTSIELGGNATLDCIVVVSGTLPDFRWLKWDKVPSTY 485

Query: 3186 ----YHNG-----QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
                 +NG      P+ + T I+    +G V L +      D G Y C   N  G+D+  
Sbjct: 486  PELDLNNGSYTLIDPVYYRT-IEAGETYG-VQLTVVNVTKKDLGLYTCYVSNHIGKDYVS 543

Query: 3237 ATIN 3240
            A ++
Sbjct: 544  AFLS 547



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 1/89 (1%)

Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVN 1776
            MK   +A   +     R    G P LR  WL++G  I+   RL    +       +K + 
Sbjct: 348  MKRAFIAWPASHSMRLRCQATGTPPLRYHWLKDGKEIKG-RRLDPYMNTTLWFFRLKDLV 406

Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            P D+G YTC   N  G    + TL V +K
Sbjct: 407  PTDTGKYTCIVSNAYGSINHTYTLRVIAK 435



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 50/194 (25%), Positives = 81/194 (41%), Gaps = 20/194 (10%)

Query: 284 QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL---RVRNTQKSDSGHYTLLA 340
           + + Q +G P  R  W K+G+ +    K   +  + +TTL   R+++   +D+G YT + 
Sbjct: 362 RLRCQATGTPPLRYHWLKDGKEI----KGRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIV 417

Query: 341 ENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQD 400
            N  G I  +  L V +   S    QR+        R T   IE+   A     V V   
Sbjct: 418 SNAYGSINHTYTLRVIAKPRSRPILQRNL------PRNTS--IELGGNATLDCIVVV--S 467

Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESGNHALMITNVTLSD 459
             + + +  ++D +V    YPE+        + D  Y   I   E+    L + NVT  D
Sbjct: 468 GTLPDFRWLKWD-KVPST-YPELDLNNGSYTLIDPVYYRTIEAGETYGVQLTVVNVTKKD 525

Query: 460 SGVVTCVARNKSGE 473
            G+ TC   N  G+
Sbjct: 526 LGLYTCYVSNHIGK 539



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 1197 LECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256
            +  R +  G P +R  W  +G+ +  G R   Y +       +      DTG+YT    N
Sbjct: 361  MRLRCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSN 419

Query: 1257 HLGSAHTSAIVRVIER 1272
              GS + +  +RVI +
Sbjct: 420  AYGSINHTYTLRVIAK 435



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 5/92 (5%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            +P+F    KS   V  G+    +C+   V        W KNG PV   HR R + +  Y 
Sbjct: 248  QPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN-RY- 303

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
             L I   +  D+G Y C   N  G    S  L
Sbjct: 304  -LKIKSTVLGDAGEYICVFNNTYGEINASIHL 334



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P FT  + +   ++ GE+A  + R +    P     W  NG  +    R R   +     
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKNR---Y 303

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            L+I  T   D+GEY+C   N YGE   +  + V+
Sbjct: 304  LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVK 337



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 6/96 (6%)

Query: 1308 MQAPQFSRALHNIETVE-GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFD 1366
            +  P+F++A+ +   V+ G +  L+CR   V        W  NG P+   HR R   +  
Sbjct: 246  LSQPKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIR-IVKNR 302

Query: 1367 YVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            Y  L + S    D+G Y C   N  GE   S  L V
Sbjct: 303  Y--LKIKSTVLGDAGEYICVFNNTYGEINASIHLDV 336



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 5/96 (5%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            PS   PKF   ++   ++  G+SA  + R   V  P     W  NG  +   HR R   +
Sbjct: 244  PSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPP--YSYWLKNGLPVVPSHRIRIVKN 301

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRDSTKANL 3372
              + I   +     ++GEY CV  N  G  +   +L
Sbjct: 302  RYLKIKSTVL---GDAGEYICVFNNTYGEINASIHL 334



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 17/50 (34%), Positives = 25/50 (50%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            P    ++  +  V+ GE AR  CR +G P P   WL NG  +V   R ++
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSYWLKNGLPVVPSHRIRI 298



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 1/66 (1%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           P +R  W KDG+ I    R+    N       +  L   D G YT    N  G    T +
Sbjct: 371 PPLRYHWLKDGKEI-KGRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYGSINHTYT 429

Query: 860 IRVAAR 865
           +RV A+
Sbjct: 430 LRVIAK 435



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 5/98 (5%)

Query: 2237 PKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHITFD 2296
            P +S P+F   ++ +  V  G++A  +C+   V  P     +  NG  +  + R  I  +
Sbjct: 244  PSLSQPKFTKAVKSSYQVKLGESARLKCRASGVPPP--YSYWLKNGLPVVPSHRIRIVKN 301

Query: 2297 FGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTV 2334
              Y  L I+  V  DAGEY     N  G   ++I + V
Sbjct: 302  -RY--LKIKSTVLGDAGEYICVFNNTYGEINASIHLDV 336



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 6/94 (6%)

Query: 1711 PVFTMPMKD-IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA 1769
            P FT  +K   +V   ++A  + R   V  P     WL+NG+P+  S+R+  + +  Y  
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN-RY-- 303

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            L +K     D+G Y C   N  GE   S  L V+
Sbjct: 304  LKIKSTVLGDAGEYICVFNNTYGEINASIHLDVK 337



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            P+F   ++S   +   E+ + +C+ + V  P     W  NG P++  +R   + +  Y+ 
Sbjct: 249  PKFTKAVKSSYQVKLGESARLKCRASGVPPPYSY--WLKNGLPVVPSHRIRIVKN-RYLK 305

Query: 4033 MNFGWVYPEDSGEYLCRATNLYG 4055
            +    +   D+GEY+C   N YG
Sbjct: 306  IKSTVL--GDAGEYICVFNNTYG 326



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 2/70 (2%)

Query: 2521 WEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGL 2580
            W   H+    R    G P LR+ W  +G E+K G R     +       +  +V  D G 
Sbjct: 355  WPASHS-MRLRCQATGTPPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGK 412

Query: 2581 YMCKAINRAG 2590
            Y C   N  G
Sbjct: 413  YTCIVSNAYG 422



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 1/63 (1%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P L+  W K+G  +  G RL    +  L    +  L   D+G YTC  +N  G    T +
Sbjct: 371  PPLRYHWLKDGKEIK-GRRLDPYMNTTLWFFRLKDLVPTDTGKYTCIVSNAYGSINHTYT 429

Query: 2732 IKI 2734
            +++
Sbjct: 430  LRV 432


>SB_31893| Best HMM Match : I-set (HMM E-Value=2e-22)
          Length = 767

 Score = 65.7 bits (153), Expect = 9e-10
 Identities = 50/182 (27%), Positives = 86/182 (47%), Gaps = 15/182 (8%)

Query: 389 ALAPQFVKVCQDRDVT-EGKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESG 446
           A  P+F++    +    +   T+ +C+V G P P VTW    D+++ ++  HK++     
Sbjct: 406 ATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEPVVTWRRTRDKKLSEE-RHKVVQG--- 461

Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVRE- 504
              L + +    D G+  C A +  G       + V   E+  A KF++   +TL ++  
Sbjct: 462 --VLYLNDPNKEDEGLYICRASSPMGSVIAAIDVTV---ERFSAVKFLKVAPATLKIKNV 516

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             P++LN  A GTP+P +TW KD V  +P   L+   D   +   I R  ++D   Y C 
Sbjct: 517 NTPIILNCTAKGTPSPTLTWYKDDV-ALPTKILK-DEDEFTAVYTIQRPSSADQGKYFCA 574

Query: 565 AQ 566
           A+
Sbjct: 575 AK 576



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 69/290 (23%), Positives = 107/290 (36%), Gaps = 35/290 (12%)

Query: 4510 GIVPPSFTLTAQ-NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT 4568
            G V P+ T+     + + +G       K +G    D YW K G +          E   +
Sbjct: 321  GFVAPNITVKPPPKITLKAGSPFTFTAKASGFPVPDTYWTKEGSR----------EAIFS 370

Query: 4569 YTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEP 4628
             TL   +A P+DSG +   A N+ G AR   + +V   ATK             P+ IE 
Sbjct: 371  STLGFSKAQPEDSGTWVFNAKNAMGSARAATDIIV---ATK-------------PKFIEK 414

Query: 4629 LKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
               K+ A +  + +  CK+ G P P V W    +  +  K  +      +  L +++   
Sbjct: 415  PPSKVTAFQSTSTKLECKVEGYPEPVVTW----RRTRDKKLSEERHKVVQGVLYLNDPNK 470

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK 4747
            EDEG Y C A +  G V  A  + V +   A     + P    +     P          
Sbjct: 471  EDEGLYICRASSPMGSVIAAIDVTV-ERFSAVKFLKVAPATLKIKNVNTPIILNCTAKGT 529

Query: 4748 IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
              PT+ W ++   +P         +   AV  I      D G + C A T
Sbjct: 530  PSPTLTWYKDDVALP--TKILKDEDEFTAVYTIQRPSSADQGKYFCAAKT 577



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 31/224 (13%)

Query: 4476 EDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDT 4535
            EDS  +   A+N  G+A+ + +++V  K +       PPS     Q+ +       +L+ 
Sbjct: 381  EDSGTWVFNAKNAMGSARAATDIIVATKPKFIE---KPPSKVTAFQSTS------TKLEC 431

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            KV G     V W +   K   + R+K+++      L + +   +D G Y C A +  G  
Sbjct: 432  KVEGYPEPVVTWRRTRDKKLSEERHKVVQG----VLYLNDPNKEDEGLYICRASSPMGSV 487

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
                  + ++  T ++         AP  +      KI      I  +C   G P PT+ 
Sbjct: 488  ------IAAIDVTVERFSAVKFLKVAPATL------KIKNVNTPIILNCTAKGTPSPTLT 535

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYT--LRISEAFPEDEGDYKCVA 4697
            WYK D  + P+K   + +  DE+T    I      D+G Y C A
Sbjct: 536  WYKDDVAL-PTK---ILKDEDEFTAVYTIQRPSSADQGKYFCAA 575



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 45/193 (23%), Positives = 79/193 (40%), Gaps = 22/193 (11%)

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTAD-EYT 4679
            AP   ++P     +  G    F+ K  G P+P   W K           + SR A    T
Sbjct: 324  APNITVKPPPKITLKAGSPFTFTAKASGFPVPDTYWTK-----------EGSREAIFSST 372

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPA 4738
            L  S+A PED G +   A N+ G    A  + V T+P   +  P+      +  ++    
Sbjct: 373  LGFSKAQPEDSGTWVFNAKNAMGSARAATDIIVATKPKFIEKPPS-----KVTAFQSTST 427

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
            + + ++    +P + W R      +    +  H+    VL + +  +ED G + CRA++ 
Sbjct: 428  KLECKVEGYPEPVVTWRRTR----DKKLSEERHKVVQGVLYLNDPNKEDEGLYICRASSP 483

Query: 4799 AGQVETSAKLVVK 4811
             G V  +  + V+
Sbjct: 484  MGSVIAAIDVTVE 496



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 48/223 (21%), Positives = 84/223 (37%), Gaps = 17/223 (7%)

Query: 4394 AQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKN 4453
            A    R     +  +KP    K       F+    + E + +G P P++ W R      +
Sbjct: 393  AMGSARAATDIIVATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEPVVTWRRTRDKKLS 452

Query: 4454 SPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP 4513
                ++     + +L +     ED  ++   A +  G+   + ++ VE         + P
Sbjct: 453  EERHKV----VQGVLYLNDPNKEDEGLYICRASSPMGSVIAAIDVTVERFSAVKFLKVAP 508

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
               TL  +NVN      + L+    GT    + W K+       +  KIL+++  +T + 
Sbjct: 509  A--TLKIKNVNTP----IILNCTAKGTPSPTLTWYKD----DVALPTKILKDEDEFTAVY 558

Query: 4574 LEAYPQ--DSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
                P   D GKY C A     E        +SL A K+ P+P
Sbjct: 559  TIQRPSSADQGKYFCAAKTKFLEKPIGYFTQLSLAACKE-PEP 600



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 7/115 (6%)

Query: 3825 IVSTPPKFITQIKSH-TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            IV+T PKFI +  S  T  +S   + EC+VE   +P   + W R      S  R++ V  
Sbjct: 404  IVATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEPV--VTWRRTRDKKLSEERHKVVQG 461

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMK 3938
            + +++        ED G YICRA +  G       ++ ++   +      P  +K
Sbjct: 462  VLYLNDP----NKEDEGLYICRASSPMGSVIAAIDVTVERFSAVKFLKVAPATLK 512



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 21/92 (22%), Positives = 43/92 (46%), Gaps = 5/92 (5%)

Query: 266 PKIAQKPRNSKLQ-EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PK  +KP +     +    + + ++ G P P VTW +   + ++  +H+++       L 
Sbjct: 409 PKFIEKPPSKVTAFQSTSTKLECKVEGYPEPVVTWRRTRDKKLSEERHKVV----QGVLY 464

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE 356
           + +  K D G Y   A +P G ++ +  + VE
Sbjct: 465 LNDPNKEDEGLYICRASSPMGSVIAAIDVTVE 496



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 6/105 (5%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            R   ++ V   P+FI +        +  S   EC++E YP+P   V W        S  R
Sbjct: 398  RAATDIIVATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEP--VVTWRRTRDKKLSEER 455

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            ++         L +     ED G Y C+A + +G  +++I + V+
Sbjct: 456  HKVVQ----GVLYLNDPNKEDEGLYICRASSPMGSVIAAIDVTVE 496



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 9/95 (9%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHR 1492
            TDII   V  KP+F+ +P S     +      ECK+E   +    V W +         R
Sbjct: 401  TDII---VATKPKFIEKPPSKVTAFQSTSTKLECKVEGYPEP--VVTWRRTRDKKLSEER 455

Query: 1493 FRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527
             + +    Y    + D   ED G+Y CRA + +G+
Sbjct: 456  HKVVQGVLY----LNDPNKEDEGLYICRASSPMGS 486



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 6/80 (7%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           Q  + K E K+ G P PVV+W R +       K S   ++    V L +      DEG Y
Sbjct: 423 QSTSTKLECKVEGYPEPVVTWRRTRD-----KKLSEERHKVVQGV-LYLNDPNKEDEGLY 476

Query: 145 TCTARNQYGEAICSVYIQPE 164
            C A +  G  I ++ +  E
Sbjct: 477 ICRASSPMGSVIAAIDVTVE 496



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 6/90 (6%)

Query: 3966 DVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPI 4025
            D+     P+F+ +  S+ +  +  +TK EC++   G P   V W       L + R   +
Sbjct: 402  DIIVATKPKFIEKPPSKVTAFQSTSTKLECKVE--GYPEPVVTWRRTRDKKLSEERHKVV 459

Query: 4026 YDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
               G + +N      ED G Y+CRA++  G
Sbjct: 460  Q--GVLYLND--PNKEDEGLYICRASSPMG 485


>SB_34975| Best HMM Match : F5_F8_type_C (HMM E-Value=0)
          Length = 909

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 50/205 (24%), Positives = 84/205 (40%), Gaps = 23/205 (11%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P FT   ++  +  G  V      +G     + WL NG    P   +++   +G+  +  
Sbjct: 584  PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQL--SNGSLNVAA 641

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKI 4633
            +       G Y C+A + AG A+ +A  +V +P                P ++    +  
Sbjct: 642  VYNNGSYEGLYTCLASSEAGMAQSNASLIVDVP----------------PSVLSLRGNST 685

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V   Q I  +C + G P P V W K  ++I  +   + +RT      R++     DEG Y
Sbjct: 686  VILEQTINLTCLVRGDPTPAVYWKKDGQIITTATLSENNRTLTTQAFRVA-----DEGRY 740

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQA 4718
             C A N AG  + +  + VT+  QA
Sbjct: 741  ACFATNRAGNDSKSILITVTECQQA 765



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 50/180 (27%), Positives = 78/180 (43%), Gaps = 13/180 (7%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+F +  + + + +G    F C  +GRP P +TW  N        +H+ L N S N A +
Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQ-LSNGSLNVAAV 642

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
             N   S  G+ TC+A +++G       L +++    V P  +       V   + + L 
Sbjct: 643 YNNG--SYEGLYTCLASSEAGMAQSNASL-IVD----VPPSVLSLRGNSTVILEQTINLT 695

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
               G PTP + W+KDG  II    L  +      TL     + +D   Y C A N AG+
Sbjct: 696 CLVRGDPTPAVYWKKDG-QIITTATLSENN----RTLTTQAFRVADEGRYACFATNRAGN 750



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+  + PR+  +++G    F    SG P+PR+TW  NG   +    H++  ++    +  
Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQL--SNGSLNVAA 641

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
                S  G YT LA +  G   ++  L V+ P
Sbjct: 642 VYNNGSYEGLYTCLASSEAGMAQSNASLIVDVP 674



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 48/192 (25%), Positives = 74/192 (38%), Gaps = 20/192 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLR 4681
            PE     + + + +G  + F C   G+P P + W Y G   + P    Q+S      +L 
Sbjct: 584  PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDAL-PQGSHQLSNG----SLN 638

Query: 4682 ISEAFPED--EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR-DIVVYEGQPA 4738
            ++  +     EG Y C+A + AG     A L V  P      P++  LR +  V   Q  
Sbjct: 639  VAAVYNNGSYEGLYTCLASSEAGMAQSNASLIVDVP------PSVLSLRGNSTVILEQTI 692

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
                 +     P + W ++G +I        + E NN  L        D G + C AT  
Sbjct: 693  NLTCLVRGDPTPAVYWKKDGQIITTA----TLSE-NNRTLTTQAFRVADEGRYACFATNR 747

Query: 4799 AGQVETSAKLVV 4810
            AG    S  + V
Sbjct: 748  AGNDSKSILITV 759



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 46/183 (25%), Positives = 66/183 (36%), Gaps = 17/183 (9%)

Query: 4411 PIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            P FT+  +   + +     F     G P P I W             Q+   S     + 
Sbjct: 584  PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQLSNGSLNVAAVY 643

Query: 4471 RQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQL 4530
                 E   ++  +A +  G A+ +A+L+V+          VPPS      N  V   Q 
Sbjct: 644  NNGSYE--GLYTCLASSEAGMAQSNASLIVD----------VPPSVLSLRGNSTVILEQT 691

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            + L   V G     VYW K+G+     I    L E+   TL        D G+Y C A N
Sbjct: 692  INLTCLVRGDPTPAVYWKKDGQ----IITTATLSENNR-TLTTQAFRVADEGRYACFATN 746

Query: 4591 SAG 4593
             AG
Sbjct: 747  RAG 749



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 10/91 (10%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKP-LPSGTRYKSTHDFSYVSLD 2834
            F  H  +   K+G+++ F C    S  P  +I W +N    LP G+     H  S  SL+
Sbjct: 586  FTRHPRSQTIKQGNHVAFGCAA--SGRPQPRITWLYNGSDALPQGS-----HQLSNGSLN 638

Query: 2835 ITHTYEEDS--GIYTCKATNSKGSATTSGSL 2863
            +   Y   S  G+YTC A++  G A ++ SL
Sbjct: 639  VAAVYNNGSYEGLYTCLASSEAGMAQSNASL 669



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 16/50 (32%), Positives = 28/50 (56%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            P F   P + T+++G    F C  +G P+PR+ WL NG+  +    ++L+
Sbjct: 584  PEFTRHPRSQTIKQGNHVAFGCAASGRPQPRITWLYNGSDALPQGSHQLS 633



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 12/116 (10%)

Query: 2625 AMNKVPEMFVDTGVQQA---PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKN 2681
            A+N V +    + V Q    P FT H +S   + +G HV        R  P  +I W  N
Sbjct: 564  AVNNVDDKGAVSAVIQVLFEPEFTRHPRS-QTIKQGNHVAFGCAASGRPQP--RITWLYN 620

Query: 2682 GVTLTTGARLKSTFDFGLVTLSINSLRNDDS--GIYTCKATNLLGEAVSTASIKIE 2735
            G    + A  + +      +L++ ++ N+ S  G+YTC A++  G A S AS+ ++
Sbjct: 621  G----SDALPQGSHQLSNGSLNVAAVYNNGSYEGLYTCLASSEAGMAQSNASLIVD 672



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGK-LLPSGHRYRTVYDMGFVS 3888
            P+F    +S T+++   V F C    +  P  RI W  NG   LP G      + +   S
Sbjct: 584  PEFTRHPRSQTIKQGNHVAFGCAASGRPQP--RITWLYNGSDALPQGS-----HQLSNGS 636

Query: 3889 LDILYVYAEDS--GEYICRAVNDFGEDFTKATISCKKLPDII 3928
            L++  VY   S  G Y C A ++ G   + A++     P ++
Sbjct: 637  LNVAAVYNNGSYEGLYTCLASSEAGMAQSNASLIVDVPPSVL 678



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 6/93 (6%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLT-GSRVKTINDFGFVI 3616
            PEFT  P    + + +   F C          R+ W +NG   L  GS   +        
Sbjct: 584  PEFTRHPRSQTIKQGNHVAFGCAAS--GRPQPRITWLYNGSDALPQGSHQLSNGSLNVAA 641

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            +   G Y+   GLYTC A++  G A  +  L V
Sbjct: 642  VYNNGSYE---GLYTCLASSEAGMAQSNASLIV 671



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 30/129 (23%), Positives = 53/129 (41%), Gaps = 11/129 (8%)

Query: 3112 GTKTTDSGTYSCRATNKW-GQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFE 3170
            GT   D+G Y+C A N    +  +S  ++ +      +P FT H ++ + +K G    F 
Sbjct: 551  GTTYADAGNYTCHAVNNVDDKGAVSAVIQVL-----FEPEFTRHPRS-QTIKQGNHVAFG 604

Query: 3171 CTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKY 3230
            C       P  +I W +NG         +  +  G + +   Y      G Y C A ++ 
Sbjct: 605  CAA--SGRPQPRITWLYNGSDALPQGSHQLSN--GSLNVAAVYNNGSYEGLYTCLASSEA 660

Query: 3231 GEDFTRATI 3239
            G   + A++
Sbjct: 661  GMAQSNASL 669



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 8/100 (8%)

Query: 1305 ITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYE 1364
            I V+  P+F+R   +    +G +V   C     G    R+ W  NG         + +++
Sbjct: 578  IQVLFEPEFTRHPRSQTIKQGNHVAFGCAAS--GRPQPRITWLYNGSDALP----QGSHQ 631

Query: 1365 FDYVALDLLSVYPEDS--GVYTCQATNQLGEAVTSCALRV 1402
                +L++ +VY   S  G+YTC A+++ G A ++ +L V
Sbjct: 632  LSNGSLNVAAVYNNGSYEGLYTCLASSEAGMAQSNASLIV 671



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F    +S T  +G  + F       G P  +I WL NG   +A  + +     G +++
Sbjct: 584 PEFTRHPRSQTIKQGNHVAFGCAAS--GRPQPRITWLYNGS--DALPQGSHQLSNGSLNV 639

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             +  N    G YTC A S  G+A++ A L V
Sbjct: 640 AAVYNNGSYEGLYTCLASSEAGMAQSNASLIV 671



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 5/91 (5%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P FT   +    + +G  V F C     G P  RI W +NG   A     H L++ G + 
Sbjct: 584  PEFTRHPRSQT-IKQGNHVAFGCAAS--GRPQPRITWLYNGSD-ALPQGSHQLSN-GSLN 638

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            +   Y      G YTC A+++ G A + A +
Sbjct: 639  VAAVYNNGSYEGLYTCLASSEAGMAQSNASL 669



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 5/74 (6%)

Query: 2669 RTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVS 2728
            R DP   + W K+G  +TT     +T      TL+  + R  D G Y C ATN  G    
Sbjct: 699  RGDPTPAVYWKKDGQIITT-----ATLSENNRTLTTQAFRVADEGRYACFATNRAGNDSK 753

Query: 2729 TASIKIEDRHWLLG 2742
            +  I + +    LG
Sbjct: 754  SILITVTECQQALG 767



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 6/73 (8%)

Query: 1738 GDPKLRVEWLRNGVPI--EASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            G P+ R+ WL NG     + S++L+     G + +   Y N    G YTC A +E G A 
Sbjct: 609  GRPQPRITWLYNGSDALPQGSHQLSN----GSLNVAAVYNNGSYEGLYTCLASSEAGMAQ 664

Query: 1796 TSSTLFVQSKASL 1808
            ++++L V    S+
Sbjct: 665  SNASLIVDVPPSV 677



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 5/81 (6%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP +     NS +           + G+P P V W K+GQ +  +   E     N+ TL 
Sbjct: 674 PPSVLSLRGNSTVILEQTINLTCLVRGDPTPAVYWKKDGQIITTATLSE-----NNRTLT 728

Query: 325 VRNTQKSDSGHYTLLAENPNG 345
            +  + +D G Y   A N  G
Sbjct: 729 TQAFRVADEGRYACFATNRAG 749



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 5/65 (7%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            GD T  V W KDG+ +      T   +     LT ++  V D G Y C A N  G  + S
Sbjct: 700  GDPTPAVYWKKDGQIIT-----TATLSENNRTLTTQAFRVADEGRYACFATNRAGNDSKS 754

Query: 997  ANLTI 1001
              +T+
Sbjct: 755  ILITV 759



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 44/188 (23%), Positives = 72/188 (38%), Gaps = 22/188 (11%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTI--EASHRIRTVYAFGM 3105
            PEFT   +    I +G   H       +G     I W YNG     + SH++      G 
Sbjct: 584  PEFTRHPRSQT-IKQGN--HVAFGCAASGRPQPRITWLYNGSDALPQGSHQLSN----GS 636

Query: 3106 VVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQ 3165
            + +  +    +  G Y+C A+++ G A+ +  L  VD      P     ++    +   Q
Sbjct: 637  LNVAAVYNNGSYEGLYTCLASSEAGMAQSNASL-IVDV-----PPSVLSLRGNSTVILEQ 690

Query: 3166 SAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            + +  C V    DP   + W  +GQ +  +T  +           +A     D G Y C 
Sbjct: 691  TINLTCLVR--GDPTPAVYWKKDGQIITTATLSENNRTLTTQAFRVA-----DEGRYACF 743

Query: 3226 AYNKYGED 3233
            A N+ G D
Sbjct: 744  ATNRAGND 751


>SB_17403| Best HMM Match : I-set (HMM E-Value=0)
          Length = 671

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 79/349 (22%), Positives = 125/349 (35%), Gaps = 54/349 (15%)

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTA 4520
            T +T   L+I  +   +S  +   A N G      AN  +  +         PP   + +
Sbjct: 285  TIATGEHLVINNINRSESGDYLCTASN-GVLGSALANATINVQ--------YPPFIEVIS 335

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580
            +   +T  Q + L    TG     + W K       D+   +L      T+  ++    D
Sbjct: 336  RIPPITENQTLELYCNATGNPAPAIRWSKGS-----DVT--VLSSGNPLTIRRVQGV--D 386

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
             G Y C A N  G    DA    ++              +   ++I+P + + V EGQ  
Sbjct: 387  QGVYVCTASNGIG---LDASSTTTVEVL----------VSPVIDVIQP-RSQTVIEGQPA 432

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
               C   G PLP + W +G+           S      TL+I+ A   + G ++C A N 
Sbjct: 433  SMYCNATGNPLPNITWTRGNG----------SLVTSGMTLQITAAHRRETGTFRCTADNG 482

Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
              R   A   KVT   Q   +  + P +D  + E  P       T    P I W++ G+ 
Sbjct: 483  VIRTAXA---KVTLDVQYPPMIHIGP-KDQTLNESNPLSLYCNATGNPSPNITWIKTGS- 537

Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809
                   Q +  G+   L I  T   D G + C A    G    +  +V
Sbjct: 538  -------QNVTVGHGHTLSINKTMTSDEGVYACVAENGVGLPSNATAMV 579



 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 68/308 (22%), Positives = 105/308 (34%), Gaps = 36/308 (11%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP  E I +     +    +      GNP P + W++     V            +G+  
Sbjct: 328 PPFIEVISRIPPITENQTLELYCNATGNPAPAIRWSKGSDVTVL----------SSGN-P 376

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKA 190
           L I+++   D+G Y CTA N  G    S                     +  S+TV    
Sbjct: 377 LTIRRVQGVDQGVYVCTASNGIGLDASST------TTVEVLVSPVIDVIQPRSQTVIEGQ 430

Query: 191 YGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDV 250
             +  Y          + +T G     T    +       +     RE+ T R   ++ V
Sbjct: 431 PASM-YCNATGNPLPNITWTRGNGSLVTSGMTLQ------ITAAHRRETGTFRCTADNGV 483

Query: 251 QISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
             +     +L    PP I   P++  L E          +GNP P +TW K G +     
Sbjct: 484 IRTAXAKVTLDVQYPPMIHIGPKDQTLNESNPLSLYCNATGNPSPNITWIKTGSQ----- 538

Query: 311 KHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN----PNGCIVTSGYLAVESPTESYVQDQ 366
              +   H H TL +  T  SD G Y  +AEN    P+        +A  +P    +Q  
Sbjct: 539 --NVTVGHGH-TLSINKTMTSDEGVYACVAENGVGLPSNATAMVTIIAFTAPVFDVIQPN 595

Query: 367 RSQYITDT 374
            +   TDT
Sbjct: 596 TTTNETDT 603



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 54/187 (28%), Positives = 72/187 (38%), Gaps = 29/187 (15%)

Query: 388 KALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
           + L    + V Q R  T  EG+     C  TG P P +TW   +  +            +
Sbjct: 409 EVLVSPVIDVIQPRSQTVIEGQPASMYCNATGNPLPNITWTRGNGSL-----------VT 457

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAF-QCRLNVIEKEQV-VAPKFVERFSTLNVR 503
               L IT     ++G   C A N    TA  +  L+V     + + PK      TLN  
Sbjct: 458 SGMTLQITAAHRRETGTFRCTADNGVIRTAXAKVTLDVQYPPMIHIGPKD----QTLN-- 511

Query: 504 EGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQC 563
           E  P+ L   A G P+P ITW K G   +        T G   TL I +   SD   Y C
Sbjct: 512 ESNPLSLYCNATGNPSPNITWIKTGSQNV--------TVGHGHTLSINKTMTSDEGVYAC 563

Query: 564 TAQNVAG 570
            A+N  G
Sbjct: 564 VAENGVG 570



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 53/184 (28%), Positives = 72/184 (39%), Gaps = 26/184 (14%)

Query: 392 PQFVKVCQD-RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           P F++V      +TE +     C  TG P P + W              + V  SGN  L
Sbjct: 328 PPFIEVISRIPPITENQTLELYCNATGNPAPAIRW---------SKGSDVTVLSSGN-PL 377

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREGEPVV 509
            I  V   D GV  C A N  G  A     +    E +V+P   V +  +  V EG+P  
Sbjct: 378 TIRRVQGVDQGVYVCTASNGIGLDAS----STTTVEVLVSPVIDVIQPRSQTVIEGQPAS 433

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           +   A G P P ITW +    ++        T G   TL I  A   +   ++CTA N  
Sbjct: 434 MYCNATGNPLPNITWTRGNGSLV--------TSG--MTLQITAAHRRETGTFRCTADNGV 483

Query: 570 GSTA 573
             TA
Sbjct: 484 IRTA 487



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 11/126 (8%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
           +D+ + E       C  TG P P +TW     Q          V     H L I     S
Sbjct: 506 KDQTLNESNPLSLYCNATGNPSPNITWIKTGSQN---------VTVGHGHTLSINKTMTS 556

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           D GV  CVA N  G  +    +  I      AP F          E + +VL+  A G P
Sbjct: 557 DEGVYACVAENGVGLPSNATAMVTIIA--FTAPVFDVIQPNTTTNETDTIVLHCNATGNP 614

Query: 519 TPRITW 524
            PRI+W
Sbjct: 615 PPRISW 620



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 83/379 (21%), Positives = 128/379 (33%), Gaps = 60/379 (15%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            + E++         G P P I+W         S    +   S+ + L IR+V   D  V+
Sbjct: 340  ITENQTLELYCNATGNPAPAIRW---------SKGSDVTVLSSGNPLTIRRVQGVDQGVY 390

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
               A N  G    S+   VE         + P    +  ++  V  GQ   +    TG  
Sbjct: 391  VCTASNGIGL-DASSTTTVEVL-------VSPVIDVIQPRSQTVIEGQPASMYCNATGNP 442

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
              ++ W +          N  L   G  TL I  A+ +++G + C A N           
Sbjct: 443  LPNITWTRG---------NGSLVTSGM-TLQITAAHRRETGTFRCTADNG---------- 482

Query: 4602 VVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDK 4661
            V+     K      T     PP I    KD+ + E   +   C   G P P + W K   
Sbjct: 483  VIRTAXAK-----VTLDVQYPPMIHIGPKDQTLNESNPLSLYCNATGNPSPNITWIKTGS 537

Query: 4662 LIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL 4721
                    Q       +TL I++    DEG Y CVA N  G  + A  +       A   
Sbjct: 538  --------QNVTVGHGHTLSINKTMTSDEGVYACVAENGVGLPSNATAMVTIIAFTAPVF 589

Query: 4722 PALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIG 4781
              + P  +    E          T    P I W    ++  ++   Q+  E     ++I 
Sbjct: 590  DVIQP--NTTTNETDTIVLHCNATGNPPPRISW----SISEQSGQRQLTGE----KVIIQ 639

Query: 4782 NTYEEDTGTFTCRATTAAG 4800
            N    +TG + C A+   G
Sbjct: 640  NILRNNTGIYRCTASNGVG 658



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 53/220 (24%), Positives = 83/220 (37%), Gaps = 29/220 (13%)

Query: 364 QDQRSQYITDTQQRETEERIEISEKALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPE 422
           +   ++Y    + + +     +    L P  V  + ++    EG      C V G P P 
Sbjct: 128 ESDHARYRCSIESKMSLSPASVKLNVLVPATVVWISENESFIEGASVTLSCWVKGNPVPY 187

Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           VTW+  +  +  +         S N++  IT + L   G   C  +N  G      ++  
Sbjct: 188 VTWYSPNGTLLHN------ATNSNNNSYTITGLRLDHVGAYRCFTKNVHGT---DDKITY 238

Query: 483 IEKEQVVAPKFVERFSTL-NVREGEPVVLNARAVGTPTPRITWQK--DGVPIIPNPELRI 539
           I     + P       TL  V E +   +   A G P P I+W K   GV I     L I
Sbjct: 239 I----YLPPSITTITPTLQTVNESDITSIYCNASGLPAPSISWSKMSSGVTIATGEHLVI 294

Query: 540 HTDGGASTLDIPRAKASDAAWYQCTAQN-VAGSTATRARL 578
           +        +I R+++ D   Y CTA N V GS    A +
Sbjct: 295 N--------NINRSESGD---YLCTASNGVLGSALANATI 323



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 11/137 (8%)

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
           D  H +LV+       +I NV  SD     C   +K   +    +LNV+    VV     
Sbjct: 107 DEGH-VLVDADAEATFIIMNVRESDHARYRCSIESKMSLSPASVKLNVLVPATVVWISEN 165

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
           E F      EG  V L+    G P P +TW      ++ N      T+   ++  I   +
Sbjct: 166 ESFI-----EGASVTLSCWVKGNPVPYVTWYSPNGTLLHNA-----TNSNNNSYTITGLR 215

Query: 555 ASDAAWYQCTAQNVAGS 571
                 Y+C  +NV G+
Sbjct: 216 LDHVGAYRCFTKNVHGT 232



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 63/304 (20%), Positives = 105/304 (34%), Gaps = 40/304 (13%)

Query: 77  IFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQI 136
           I +N  F +G +      ++GNP P V+W      L+  N  +   N  T      I  +
Sbjct: 162 ISENESFIEGASVTLSCWVKGNPVPYVTWYSPNGTLLH-NATNSNNNSYT------ITGL 214

Query: 137 GPGDEGEYTCTARNQYG--EAICSVYIQPEGXXXXXXXXXXXXXYRHVSETVEHKAYGTQ 194
                G Y C  +N +G  + I  +Y+ P                    +TV      T 
Sbjct: 215 RLDHVGAYRCFTKNVHGTDDKITYIYLPP-----------SITTITPTLQTVNESDI-TS 262

Query: 195 GYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGESDVQIST 254
            Y          ++++       +    + T E+ ++  ++  ES        + V  S 
Sbjct: 263 IYCNASGLPAPSISWS-----KMSSGVTIATGEHLVINNINRSESGDYLCTASNGVLGSA 317

Query: 255 EIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
             + ++    PP I    R   + E    +     +GNP P + W K           ++
Sbjct: 318 LANATINVQYPPFIEVISRIPPITENQTLELYCNATGNPAPAIRWSKGS---------DV 368

Query: 315 ITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVE---SPTESYVQDQRSQYI 371
               +   L +R  Q  D G Y   A N  G +  S    VE   SP    +Q  RSQ +
Sbjct: 369 TVLSSGNPLTIRRVQGVDQGVYVCTASNGIG-LDASSTTTVEVLVSPVIDVIQ-PRSQTV 426

Query: 372 TDTQ 375
            + Q
Sbjct: 427 IEGQ 430



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 1/52 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSRYKLT 4160
            P + V  P + TV EG+ A   C  TG+P P + W   NG+ + +G   ++T
Sbjct: 414  PVIDVIQPRSQTVIEGQPASMYCNATGNPLPNITWTRGNGSLVTSGMTLQIT 465



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 11/85 (12%)

Query: 2374 QRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGY 2433
            Q P F + +  I  I E QT    C     G+P   + W +   +   SS          
Sbjct: 326  QYPPFIEVISRIPPITENQTLELYCNA--TGNPAPAIRWSKGSDVTVLSSGNP------- 376

Query: 2434 VSMTISHVRDEDEGVYMCRASNLLG 2458
              +TI  V+  D+GVY+C ASN +G
Sbjct: 377  --LTIRRVQGVDQGVYVCTASNGIG 399



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 29/114 (25%), Positives = 46/114 (40%), Gaps = 8/114 (7%)

Query: 234 VSFRESITKRYVGESDVQIS-TEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGN 292
           ++ RES   RY    + ++S +     L  + P  +     N    EGA       + GN
Sbjct: 124 MNVRESDHARYRCSIESKMSLSPASVKLNVLVPATVVWISENESFIEGASVTLSCWVKGN 183

Query: 293 PRPRVTWFK-NGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           P P VTW+  NG  L N+      T  N+ +  +   +    G Y    +N +G
Sbjct: 184 PVPYVTWYSPNGTLLHNA------TNSNNNSYTITGLRLDHVGAYRCFTKNVHG 231



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 46/191 (24%), Positives = 64/191 (33%), Gaps = 27/191 (14%)

Query: 4622 PPEI--IEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            PP I  I P   + V E       C   G P P++ W         SK       A    
Sbjct: 242  PPSITTITPTL-QTVNESDITSIYCNASGLPAPSISW---------SKMSSGVTIATGEH 291

Query: 4680 LRISEAFPEDEGDYKCVAYNSA-GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPA 4738
            L I+     + GDY C A N   G     A + V  P   + +  + P     + E Q  
Sbjct: 292  LVINNINRSESGDYLCTASNGVLGSALANATINVQYPPFIEVISRIPP-----ITENQTL 346

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
            +     T    P I+W +         D  ++  GN   L I      D G + C A+  
Sbjct: 347  ELYCNATGNPAPAIRWSKGS-------DVTVLSSGN--PLTIRRVQGVDQGVYVCTASNG 397

Query: 4799 AGQVETSAKLV 4809
             G   +S   V
Sbjct: 398  IGLDASSTTTV 408



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 63/287 (21%), Positives = 103/287 (35%), Gaps = 50/287 (17%)

Query: 4422 VFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            V E + A       G PLP I W R N  +  S             L I      ++  F
Sbjct: 426  VIEGQPASMYCNATGNPLPNITWTRGNGSLVTSG----------MTLQITAAHRRETGTF 475

Query: 4482 AAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTK 4541
               A+N G      A + ++ +         PP   +  ++  +     + L    TG  
Sbjct: 476  RCTADN-GVIRTAXAKVTLDVQ--------YPPMIHIGPKDQTLNESNPLSLYCNATGNP 526

Query: 4542 PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAEC 4601
              ++ W+K G +        +    G +TL I +    D G Y CVA N  G    +A  
Sbjct: 527  SPNITWIKTGSQ-------NVTVGHG-HTLSINKTMTSDEGVYACVAENGVG-LPSNATA 577

Query: 4602 VVSLPATKDKPKPQTKAANAPP-EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD 4660
            +V++            A  AP  ++I+P  +    E   I   C   G P P + W    
Sbjct: 578  MVTI-----------IAFTAPVFDVIQP--NTTTNETDTIVLHCNATGNPPPRISW---- 620

Query: 4661 KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
             + + S   Q+  T ++  + I      + G Y+C A N  G   ++
Sbjct: 621  SISEQSGQRQL--TGEK--VIIQNILRNNTGIYRCTASNGVGNDVIS 663



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 12/100 (12%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I+   P F++ +S  PP++E + + L C     G+P   + W   G  VTV S       
Sbjct: 323  INVQYPPFIEVISRIPPITENQTLELYC--NATGNPAPAIRW-SKGSDVTVLSSGN---- 375

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHLG-SAHTSAIVRVI 1270
                 L I      D G Y   A N +G  A ++  V V+
Sbjct: 376  ----PLTIRRVQGVDQGVYVCTASNGIGLDASSTTTVEVL 411



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/93 (24%), Positives = 40/93 (43%), Gaps = 10/93 (10%)

Query: 391 APQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           AP F  +  +    E       C  TG P P ++W I+++        + L  E     +
Sbjct: 586 APVFDVIQPNTTTNETDTIVLHCNATGNPPPRISWSISEQS-----GQRQLTGEK----V 636

Query: 451 MITNVTLSDSGVVTCVARNKSG-ETAFQCRLNV 482
           +I N+  +++G+  C A N  G +   Q  +NV
Sbjct: 637 IIQNILRNNTGIYRCTASNGVGNDVISQAHINV 669



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 14/67 (20%)

Query: 2672 PNLKIEWFK--NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN-LLGEAVS 2728
            P   I W K  +GVT+ TG  L            IN++   +SG Y C A+N +LG A++
Sbjct: 271  PAPSISWSKMSSGVTIATGEHLV-----------INNINRSESGDYLCTASNGVLGSALA 319

Query: 2729 TASIKIE 2735
             A+I ++
Sbjct: 320  NATINVQ 326



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 11/98 (11%)

Query: 1981 GKPIKNAEVTEGHPVHLE--ATLTPVNDPTMRVEWYCN--GRPVQQGHRFKTTYDFGYVA 2036
            G  + NA +   +P  +E  + + P+ +    +E YCN  G P     R+    D   ++
Sbjct: 315  GSALANATINVQYPPFIEVISRIPPITE-NQTLELYCNATGNPAP-AIRWSKGSDVTVLS 372

Query: 2037 ----LDILYAYAEDTGTYMCKATNAVG-EAVTTSSVKV 2069
                L I      D G Y+C A+N +G +A +T++V+V
Sbjct: 373  SGNPLTIRRVQGVDQGVYVCTASNGIGLDASSTTTVEV 410


>SB_57324| Best HMM Match : ig (HMM E-Value=1e-26)
          Length = 947

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 52/196 (26%), Positives = 83/196 (42%), Gaps = 16/196 (8%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF--TLTAQNVNV 4525
            L I+   V+DS  +   A N  G    S  L+V  K       +  P F   + A  + +
Sbjct: 477  LRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLK-------VQAPVFRRNIKALRIRL 529

Query: 4526 TSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYE 4585
              G  ++L     G+    + W  NGKK++   RN ++     + L I      DSG+Y 
Sbjct: 530  EEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILRG--WVLNIRSLRQSDSGRYT 587

Query: 4586 CVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEI---IEPLKDKIVAEGQAIEF 4642
            C+  N  G  R     +VS   ++   +P  + +NAP  I      LK+K   EG  + F
Sbjct: 588  CIVKNKHGTIR--RTYIVSPLKSRSTGEPALEPSNAPNGIDINTHLLKNKTAVEGTDVTF 645

Query: 4643 SCKIVGKPLPTVQWYK 4658
            +CK V +   +  W +
Sbjct: 646  TCKAVSEVPLSFIWLR 661



 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 43/125 (34%), Positives = 61/125 (48%), Gaps = 7/125 (5%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQS 3166
            L I   +  DSG Y C+A N +G    S+ L  +   K Q P F  +I+ +   L++G  
Sbjct: 477  LRIKNARVKDSGKYLCQAHNSFGMINASITL--IVHLKVQAPVFRRNIKALRIRLEEGSQ 534

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C       P  KI+W+HNG+ +R S R   V   G+ VL+I   +  DSG Y C  
Sbjct: 535  LKLRCHA--NGSPQPKIQWHHNGKKLR-SRRRNHVILRGW-VLNIRSLRQSDSGRYTCIV 590

Query: 3227 YNKYG 3231
             NK+G
Sbjct: 591  KNKHG 595



 Score = 56.0 bits (129), Expect = 7e-07
 Identities = 59/260 (22%), Positives = 111/260 (42%), Gaps = 26/260 (10%)

Query: 276 KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGH 335
           +L+EG+  + +   +G+P+P++ W  NG++L +  ++ +I       L +R+ ++SDSG 
Sbjct: 528 RLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVIL--RGWVLNIRSLRQSDSGR 585

Query: 336 YTLLAENPNGCIVTS---GYLAVESPTESYVQDQRSQYITD--TQQRETEERIE------ 384
           YT + +N +G I  +     L   S  E  ++   +    D  T   + +  +E      
Sbjct: 586 YTCIVKNKHGTIRRTYIVSPLKSRSTGEPALEPSNAPNGIDINTHLLKNKTAVEGTDVTF 645

Query: 385 ----ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
               +SE  L+  +++     + T+G   +   R+     P V      R IR+   +  
Sbjct: 646 TCKAVSEVPLSFIWLRWTPLTNATDGTADQ-PVRILNASDPRV------RLIRESAAYWS 698

Query: 441 LVNESGN--HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFS 498
           L ++  +  H LM+ NVT  D G  +CV        ++   L V  KE        +  S
Sbjct: 699 LADKRASYCHKLMLLNVTKRDQGQYSCVVGGGKEMVSYNVFLTVKPKELRAQDSMYKNTS 758

Query: 499 TLNVREGEPVVLNARAVGTP 518
           +     GE  +  A  +  P
Sbjct: 759 SHGKSYGEFEIPLAALIAVP 778



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 38/126 (30%), Positives = 53/126 (42%), Gaps = 6/126 (4%)

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVR--EG 505
           H L I N  + DSG   C A N  G       + +I   +V AP F      L +R  EG
Sbjct: 475 HHLRIKNARVKDSGKYLCQAHNSFG--MINASITLIVHLKVQAPVFRRNIKALRIRLEEG 532

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
             + L   A G+P P+I W  +G  +      R H       L+I   + SD+  Y C  
Sbjct: 533 SQLKLRCHANGSPQPKIQWHHNGKKL--RSRRRNHVILRGWVLNIRSLRQSDSGRYTCIV 590

Query: 566 QNVAGS 571
           +N  G+
Sbjct: 591 KNKHGT 596



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 49/193 (25%), Positives = 79/193 (40%), Gaps = 8/193 (4%)

Query: 3404 MVRRKDTSVEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSL 3463
            M+    T +   K +APVF   +  +  +R  E +  + R      P  K++W+ NGK L
Sbjct: 500  MINASITLIVHLKVQAPVFRRNIKALR-IRLEEGSQLKLRCHANGSPQPKIQWHHNGKKL 558

Query: 3464 KAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTT---ASMKVQGKRNIIL 3520
            +  SR R        +L I      DSG Y C   N +G    T   + +K +      L
Sbjct: 559  R--SRRRNHVILRGWVLNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPAL 616

Query: 3521 E-SQLPKGMEGTIDKIAALEGYSGTVDTLTPEAESGNPPEFTTTP-SDLILSENSSAHFE 3578
            E S  P G++     +       GT  T T +A S  P  F     + L  + + +A   
Sbjct: 617  EPSNAPNGIDINTHLLKNKTAVEGTDVTFTCKAVSEVPLSFIWLRWTPLTNATDGTADQP 676

Query: 3579 CRLIPVNDSSMRV 3591
             R++  +D  +R+
Sbjct: 677  VRILNASDPRVRL 689



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 10/134 (7%)

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAYNSAG----RVTVAAKLKVTQPDQADNLPALTPLR 4728
            R+ + + LRI  A  +D G Y C A+NS G     +T+   LKV  P    N+ AL    
Sbjct: 470  RSMNGHHLRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLKVQAPVFRRNIKALR--- 526

Query: 4729 DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDT 4788
             I + EG   + +       +P IQW   G  +       +I  G   VL I +  + D+
Sbjct: 527  -IRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILRG--WVLNIRSLRQSDS 583

Query: 4789 GTFTCRATTAAGQV 4802
            G +TC      G +
Sbjct: 584  GRYTCIVKNKHGTI 597



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 48/198 (24%), Positives = 71/198 (35%), Gaps = 25/198 (12%)

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L I  A  +DSGKY C A NS G        +V L       +   KA     E      
Sbjct: 477  LRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLKVQAPVFRRNIKALRIRLE------ 530

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
                 EG  ++  C   G P P +QW+   K ++  +   +      + L I      D 
Sbjct: 531  -----EGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILRG--WVLNIRSLRQSDS 583

Query: 4691 GDYKCVAYNSAG---RVTVAAKLKVTQPDQADNLPALTP---------LRDIVVYEGQPA 4738
            G Y C+  N  G   R  + + LK     +    P+  P         L++    EG   
Sbjct: 584  GRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPALEPSNAPNGIDINTHLLKNKTAVEGTDV 643

Query: 4739 QFKTQITSKIKPTIQWLR 4756
             F  +  S++  +  WLR
Sbjct: 644  TFTCKAVSEVPLSFIWLR 661



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 62/252 (24%), Positives = 104/252 (41%), Gaps = 19/252 (7%)

Query: 1709 QAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            QAPVF   +K +R+   + +  + R    G P+ +++W  NG  +  S R   +   G+V
Sbjct: 514  QAPVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLR-SRRRNHVILRGWV 572

Query: 1769 ALNMKYVNPEDSGTYTCRAINELG---EAVTSSTLFVQSKASLQLE-SQHESALQKIQQL 1824
             LN++ +   DSG YTC   N+ G        S L  +S     LE S   + +     L
Sbjct: 573  -LNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPALEPSNAPNGIDINTHL 631

Query: 1825 EDSSRYQRREDVEV---AVNQAP-RFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEW 1880
              +       DV     AV++ P  FI     P   +   +A    RI    DP +R+  
Sbjct: 632  LKNKTAVEGTDVTFTCKAVSEVPLSFIWLRWTPLTNATDGTADQPVRILNASDPRVRL-- 689

Query: 1881 YFNGKVLQSGHRYRTSNDFGFAA--LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQS 1938
                 + +S   +  ++        L +L V   D G+Y+C           ++ L V+ 
Sbjct: 690  -----IRESAAYWSLADKRASYCHKLMLLNVTKRDQGQYSCVVGGGKEMVSYNVFLTVKP 744

Query: 1939 KESIIRDSQHES 1950
            KE   +DS +++
Sbjct: 745  KELRAQDSMYKN 756



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 7/88 (7%)

Query: 388 KALAPQF---VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE 444
           K  AP F   +K  + R + EG   +  C   G P P++ W  N +++R    + +++  
Sbjct: 512 KVQAPVFRRNIKALRIR-LEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILR- 569

Query: 445 SGNHALMITNVTLSDSGVVTCVARNKSG 472
                L I ++  SDSG  TC+ +NK G
Sbjct: 570 --GWVLNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P F   IK+  +   EG + + R      P+ +I+W+ NGK L S  R   +   G+V L
Sbjct: 516  PVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVIL-RGWV-L 573

Query: 3890 DILYVYAEDSGEYICRAVNDFG 3911
            +I  +   DSG Y C   N  G
Sbjct: 574  NIRSLRQSDSGRYTCIVKNKHG 595



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 5/93 (5%)

Query: 3691 KPNPPRFTVEIKD-NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            K   P F   IK   I + EG  +   C     G P  +I W HNG+   +  R H +  
Sbjct: 512  KVQAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR 569

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
             G++ L+I  +   D+G YTC   NK G+   T
Sbjct: 570  -GWV-LNIRSLRQSDSGRYTCIVKNKHGTIRRT 600



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 5/86 (5%)

Query: 2107 QRPVFLTALTSLE-NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
            Q PVF   + +L   L+EG +    C       P   I W HNG+K+R+  R       G
Sbjct: 514  QAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR-G 570

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLG 2191
            +V L+I      DSG Y C   NK G
Sbjct: 571  WV-LNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 2640 QAPIFTTHLKSYD-KLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFG 2698
            QAP+F  ++K+   +L EG  + L         P  KI+W  NG  L +  R       G
Sbjct: 514  QAPVFRRNIKALRIRLEEGSQLKLRCHANGSPQP--KIQWHHNGKKLRSRRR-NHVILRG 570

Query: 2699 LVTLSINSLRNDDSGIYTCKATNLLG 2724
             V L+I SLR  DSG YTC   N  G
Sbjct: 571  WV-LNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 2/91 (2%)

Query: 1569 MVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTE 1628
            ++  +  QAP+   ++K + I+  + +  + R         K++W+HN K L+S  R   
Sbjct: 507  LIVHLKVQAPVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRR-NH 565

Query: 1629 TNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
                G+V L+I S    DSG YTC   N  G
Sbjct: 566  VILRGWV-LNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 6/72 (8%)

Query: 3569 LSENSSAHFECRLIPVNDSSM-RVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDA 3627
            L E S     C     N S   +++W HNGK L +  R   I   G+V L I  + Q D+
Sbjct: 529  LEEGSQLKLRCH---ANGSPQPKIQWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDS 583

Query: 3628 GLYTCKATNRHG 3639
            G YTC   N+HG
Sbjct: 584  GRYTCIVKNKHG 595



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 32/109 (29%), Positives = 48/109 (44%), Gaps = 10/109 (9%)

Query: 3969 KKQPPRFVTQIQS-QTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYD 4027
            K Q P F   I++ +  L E    K  C     G P  K++W  NGK L  + R   I  
Sbjct: 512  KVQAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR 569

Query: 4028 FGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI-----KTTGKPGI 4071
             G+V +N   +   DSG Y C   N +G      ++     ++TG+P +
Sbjct: 570  -GWV-LNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPAL 616



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 29/87 (33%), Positives = 44/87 (50%), Gaps = 5/87 (5%)

Query: 650 EGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEY 709
           EG ++  + R    G P  KI+W  NG+ + +  R   I R G++ L++ SL   DSG Y
Sbjct: 531 EGSQL--KLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDSGRY 586

Query: 710 TCRAVSATG-VAETKAVLHVTPRATIE 735
           TC   +  G +  T  V  +  R+T E
Sbjct: 587 TCIVKNKHGTIRRTYIVSPLKSRSTGE 613



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 6/87 (6%)

Query: 1308 MQAPQFSRALH--NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEF 1365
            +QAP F R +    I   EG+ + L C     G    +++W  NGK +++  R       
Sbjct: 513  VQAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR- 569

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLG 1392
             +V L++ S+   DSG YTC   N+ G
Sbjct: 570  GWV-LNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 65/228 (28%), Positives = 89/228 (39%), Gaps = 48/228 (21%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDP--HLTID-WF--HNGQ-----KIRAGH 2156
            Q+P FL           GD    +C V  +NDP  + T   WF   NG+     K R G 
Sbjct: 406  QKPKFLKKPKLRYEATVGDSVKLKCLVTGVNDPLFNRTYSVWFSYRNGKTKIVGKPRRGE 465

Query: 2157 RYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNG 2216
            + R     G+  L I     +DSG Y+C+A N  G    + TL V  H    L  Q P  
Sbjct: 466  KSRFRSMNGH-HLRIKNARVKDSGKYLCQAHNSFGMINASITLIV--H----LKVQAPVF 518

Query: 2217 LEKIRQLEAQGHSTRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRI 2276
               I+ L       RI +EE                    G      C       P  +I
Sbjct: 519  RRNIKAL-------RIRLEE--------------------GSQLKLRCHANGSPQP--KI 549

Query: 2277 EFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINALG 2324
            +++HNGK L+S  R H+    G+V L+I+     D+G Y+    N  G
Sbjct: 550  QWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 30/148 (20%), Positives = 58/148 (39%), Gaps = 11/148 (7%)

Query: 4411 PIFTKKMQPCRVF--EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSIL 4468
            P+F + ++  R+   E  Q +     +G P P I+W+     +++    + H      +L
Sbjct: 516  PVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRR--RNHVILRGWVL 573

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSF-------TLTAQ 4521
             IR +   DS  +  + +N+ GT + +  +   + R  G   + P +        T   +
Sbjct: 574  NIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRSTGEPALEPSNAPNGIDINTHLLK 633

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLK 4549
            N     G  V    K     P+   WL+
Sbjct: 634  NKTAVEGTDVTFTCKAVSEVPLSFIWLR 661



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 4/72 (5%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDS 2981
            +L EG  L L  +      P  KI+W+ NGK L    R  +    G+V L++  + + DS
Sbjct: 528  RLEEGSQLKL--RCHANGSPQPKIQWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDS 583

Query: 2982 GIYTCKAYNKRG 2993
            G YTC   NK G
Sbjct: 584  GRYTCIVKNKHG 595



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 6/102 (5%)

Query: 768 QRPQFIRPLQDLG-ELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFG 826
           Q P F R ++ L   L+EG              P  +++W+ +G+ + +  R   I   G
Sbjct: 514 QAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLRSRRRNHVILR-G 570

Query: 827 YVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIR-VAARST 867
           +V LNI  LR  D+G YT    NK G    T  +  + +RST
Sbjct: 571 WV-LNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSPLKSRST 611



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTG 1248
            + EG  + L C     G P  +++W HNG+ +   SR + +       L+I     +D+G
Sbjct: 529  LEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLR--SRRRNHVILRGWVLNIRSLRQSDSG 584

Query: 1249 EYTVRAVNHLGSAHTSAIV 1267
             YT    N  G+   + IV
Sbjct: 585  RYTCIVKNKHGTIRRTYIV 603



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 1041 QKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGY 1100
            Q P F   +K     +E + +  + R          ++W+ NGK++ S  R       G+
Sbjct: 514  QAPVFRRNIKALRIRLE-EGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILR-GW 571

Query: 1101 VALDIASVRAEDSGVYTVVARNAAG 1125
            V L+I S+R  DSG YT + +N  G
Sbjct: 572  V-LNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFDIPKTRQYDTGK 4179
            + +EEG   +  C   G P+P++ W  NG  + +  R  +   G +  +I   RQ D+G+
Sbjct: 527  IRLEEGSQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILRG-WVLNIRSLRQSDSGR 585

Query: 4180 IEVI 4183
               I
Sbjct: 586  YTCI 589



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 6/84 (7%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLG---RDST 3368
            P  K++W +NGKKL    R R        +L+I    + +SG Y C+  NK G   R   
Sbjct: 545  PQPKIQWHHNGKKL--RSRRRNHVILRGWVLNIRSLRQSDSGRYTCIVKNKHGTIRRTYI 602

Query: 3369 KANLKCTSK-ENLILDSQLPRGME 3391
             + LK  S  E  +  S  P G++
Sbjct: 603  VSPLKSRSTGEPALEPSNAPNGID 626



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 12/95 (12%)

Query: 1976 EKPQF-GKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEW-----YCNGRPV-----QQGH 2024
            +KP+F  KP    E T G  V L+  +T VNDP     +     Y NG+       ++G 
Sbjct: 406  QKPKFLKKPKLRYEATVGDSVKLKCLVTGVNDPLFNRTYSVWFSYRNGKTKIVGKPRRGE 465

Query: 2025 RFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            + +     G+  L I  A  +D+G Y+C+A N+ G
Sbjct: 466  KSRFRSMNGH-HLRIKNARVKDSGKYLCQAHNSFG 499



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 5/86 (5%)

Query: 907 QKPEFKTPIKD-QISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFG 965
           Q P F+  IK  +I ++EG  +  + R    G    +++W  +G+ + +  R       G
Sbjct: 514 QAPVFRRNIKALRIRLEEG--SQLKLRCHANGSPQPKIQWHHNGKKLRSRRRNHVILR-G 570

Query: 966 YVALTIKSVTVHDAGHYTCRAYNAIG 991
           +V L I+S+   D+G YTC   N  G
Sbjct: 571 WV-LNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 4/71 (5%)

Query: 2786 KEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGI 2845
            +EG  +   C+   S  P  KI+W  N K L S  R ++        L+I    + DSG 
Sbjct: 530  EEGSQLKLRCHANGSPQP--KIQWHHNGKKLRS--RRRNHVILRGWVLNIRSLRQSDSGR 585

Query: 2846 YTCKATNSKGS 2856
            YTC   N  G+
Sbjct: 586  YTCIVKNKHGT 596



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 2/55 (3%)

Query: 3076 GDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
            G     I+W +NGK + +  R   +   G V L I   + +DSG Y+C   NK G
Sbjct: 543  GSPQPKIQWHHNGKKLRSRRRNHVILR-GWV-LNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 10/95 (10%)

Query: 3827 STPPKFITQIK-SHTVEESEGVRFECRVEPKEDP---KLRIEW--YRNGKLLPSGHRYR- 3879
            S  PKF+ + K  +     + V+ +C V    DP   +    W  YRNGK    G   R 
Sbjct: 405  SQKPKFLKKPKLRYEATVGDSVKLKCLVTGVNDPLFNRTYSVWFSYRNGKTKIVGKPRRG 464

Query: 3880 ---TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
                   M    L I     +DSG+Y+C+A N FG
Sbjct: 465  EKSRFRSMNGHHLRIKNARVKDSGKYLCQAHNSFG 499



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/94 (23%), Positives = 36/94 (38%), Gaps = 6/94 (6%)

Query: 72  PIFEQIFK--NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           P+F +  K    R  +G   K      G+P P + W      L    +   R +      
Sbjct: 516 PVFRRNIKALRIRLEEGSQLKLRCHANGSPQPKIQWHHNGKKL----RSRRRNHVILRGW 571

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQP 163
            L I+ +   D G YTC  +N++G    +  + P
Sbjct: 572 VLNIRSLRQSDSGRYTCIVKNKHGTIRRTYIVSP 605



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 15/105 (14%)

Query: 3964 LYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDP--NMKVE-WFF--NGKPLL- 4017
            ++ V+  Q P+F+ + + +      ++ K +C +  V DP  N     WF   NGK  + 
Sbjct: 399  VFGVNYSQKPKFLKKPKLRYEATVGDSVKLKCLVTGVNDPLFNRTYSVWFSYRNGKTKIV 458

Query: 4018 ------HKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGM 4056
                   K+RF  +        N      +DSG+YLC+A N +GM
Sbjct: 459  GKPRRGEKSRFRSMNGHHLRIKN---ARVKDSGKYLCQAHNSFGM 500



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 14/36 (38%), Positives = 20/36 (55%)

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            L IK+  V D+G Y C+A+N+ G    S  L +  K
Sbjct: 477  LRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLK 512



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 5/86 (5%)

Query: 2374 QRPVFTQPLQNID-NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            Q PVF + ++ +   ++EG      C     G P  K++W  N K +  S R       G
Sbjct: 514  QAPVFRRNIKALRIRLEEGSQLKLRCHAN--GSPQPKIQWHHNGKKLR-SRRRNHVILRG 570

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
            +V + I  +R  D G Y C   N  G
Sbjct: 571  WV-LNIRSLRQSDSGRYTCIVKNKHG 595



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSR 1829
            L +K    +DSG Y C+A N  G    S TL V  K    +  ++  AL+   +LE+ S+
Sbjct: 477  LRIKNARVKDSGKYLCQAHNSFGMINASITLIVHLKVQAPVFRRNIKALR--IRLEEGSQ 534

Query: 1830 YQRR 1833
             + R
Sbjct: 535  LKLR 538


>SB_2157| Best HMM Match : ig (HMM E-Value=9e-19)
          Length = 603

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 65/299 (21%), Positives = 124/299 (41%), Gaps = 38/299 (12%)

Query: 4544 DVYWLKNGKKVQPDIRNK------ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
            ++ W+K+GK + P  R+       +L +  T  L++     + +G Y C+   +      
Sbjct: 87   EIRWMKDGKLLDPRRRSTEYRDYAVLRDGNTSILMLRNVSTRHTGGYRCITSRAGKHPLS 146

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
              +C +++  + ++P+   K  +       PL+  I+   Q   F C   G+P P + W 
Sbjct: 147  FTQCFLNVTLS-ERPRILRKPLHL---FTPPLQ--ILTRDQPQTFHCYADGQPAPRLAWL 200

Query: 4658 KGDKLI-KPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR------VTVAAKL 4710
            K D +I +  K +++++ A    L I  A     G+Y C+A N  GR        ++ ++
Sbjct: 201  KDDHVIGENQKGYRLAKRARGLDLTIMLAQANSGGNYTCLAVNRLGRAEYHIWAVLSGEI 260

Query: 4711 KVTQPDQADNLPALTP--------LRDIVVYEGQPAQFKTQIT--SKIKPTIQWLREGAL 4760
             V        +  ++P        L  ++V  G PA    + T   K+     W+  G +
Sbjct: 261  NVKHIANIVEVEHISPEKPEVTAELPVVLVRFGHPANLTCRSTHAPKVYTISYWMYGGKV 320

Query: 4761 IPETPDFQMI------HEGNNAVLL---IGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
            +    D   I       +G N+++L   + N  EE  G ++C   T  G      +LV+
Sbjct: 321  VENMGDEYSITRTWGKGKGANSLMLNLQVRNVTEETAGNYSCIVQTHIGPGSADTRLVI 379



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 40/150 (26%), Positives = 65/150 (43%), Gaps = 6/150 (4%)

Query: 427 INDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCV-ARNKSGETAF-QCRLNVIE 484
           ++ R+   +Y    ++ +     LM+ NV+   +G   C+ +R      +F QC LNV  
Sbjct: 97  LDPRRRSTEYRDYAVLRDGNTSILMLRNVSTRHTGGYRCITSRAGKHPLSFTQCFLNVTL 156

Query: 485 KEQV-VAPKFVERFST-LNV-REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPE-LRIH 540
            E+  +  K +  F+  L +    +P   +  A G P PR+ W KD   I  N +  R+ 
Sbjct: 157 SERPRILRKPLHLFTPPLQILTRDQPQTFHCYADGQPAPRLAWLKDDHVIGENQKGYRLA 216

Query: 541 TDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                  L I  A+A+    Y C A N  G
Sbjct: 217 KRARGLDLTIMLAQANSGGNYTCLAVNRLG 246



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 31/130 (23%), Positives = 49/130 (37%), Gaps = 14/130 (10%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           +T  +   F C   G+P P + W  +D  I ++     L   +    L I     +  G 
Sbjct: 177 LTRDQPQTFHCYADGQPAPRLAWLKDDHVIGENQKGYRLAKRARGLDLTIMLAQANSGGN 236

Query: 463 VTCVARNK------------SGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPV 508
            TC+A N+            SGE   +   N++E E +    P+       + VR G P 
Sbjct: 237 YTCLAVNRLGRAEYHIWAVLSGEINVKHIANIVEVEHISPEKPEVTAELPVVLVRFGHPA 296

Query: 509 VLNARAVGTP 518
            L  R+   P
Sbjct: 297 NLTCRSTHAP 306



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 45/225 (20%), Positives = 81/225 (36%), Gaps = 31/225 (13%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR-YRTSNDFGFAALDILTVYGEDS 1914
            L+  Q   + C  +  P P  R+ W  +  V+    + YR +       L I+       
Sbjct: 177  LTRDQPQTFHCYADGQPAP--RLAWLKDDHVIGENQKGYRLAKRARGLDLTIMLAQANSG 234

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFV 1974
            G YTC A+N LG+A   I   +  + ++    +H + + +++++                
Sbjct: 235  GNYTCLAVNRLGRAEYHIWAVLSGEINV----KHIANIVEVEHISP-------------- 276

Query: 1975 VEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ-QGHRFKTTYDFG 2033
             EKP+    +    V  GHP +L    T          W   G+ V+  G  +  T  +G
Sbjct: 277  -EKPEVTAELPVVLVRFGHPANLTCRSTHAPKVYTISYWMYGGKVVENMGDEYSITRTWG 335

Query: 2034 --------YVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
                     + L +     E  G Y C     +G     + + +D
Sbjct: 336  KGKGANSLMLNLQVRNVTEETAGNYSCIVQTHIGPGSADTRLVID 380



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 3/60 (5%)

Query: 97  GNPTPVVSWTRKKAPLVECNK-YSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           G P P ++W +    + E  K Y +    +  D+++++ Q   G  G YTC A N+ G A
Sbjct: 191 GQPAPRLAWLKDDHVIGENQKGYRLAKRARGLDLTIMLAQANSG--GNYTCLAVNRLGRA 248



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 1/56 (1%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGY-VSLNIMHLRAEDAGSYTVRAVNKLGEA 854
           P  R+ W KD   I  + +   +      + L IM  +A   G+YT  AVN+LG A
Sbjct: 193 PAPRLAWLKDDHVIGENQKGYRLAKRARGLDLTIMLAQANSGGNYTCLAVNRLGRA 248


>SB_20844| Best HMM Match : Ion_trans (HMM E-Value=0)
          Length = 2675

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 49/170 (28%), Positives = 73/170 (42%), Gaps = 10/170 (5%)

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
            +C+  G P P+V W KG  L+  S         ++ TLRI +A  EDEG Y C A N  G
Sbjct: 707  TCRAEGNPEPSVGWKKG--LLPVSSLGPRYEILEDGTLRIEQAMIEDEGTYSCYATNFKG 764

Query: 4703 RV-TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALI 4761
             + T  A L+V  P       ++ P  +  V  G+P     Q + K  P  +W ++  LI
Sbjct: 765  PLQTRTANLRVVVPVTV----SMIPRDEHEVSVGEPLTIYCQFSGKPTPFNRWYKDSQLI 820

Query: 4762 PETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                +   I  G    + I +    D G + C+A    G+      + VK
Sbjct: 821  LNGNERISISPGQ---ISIKSVLPSDAGLYECQAIHDYGRAADFVTIKVK 867



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 57/192 (29%), Positives = 79/192 (41%), Gaps = 25/192 (13%)

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQP-DIRNKILEEDGTYTLLILEAYPQDSGKYECVAI 4589
            V L  +  G     V W K    V     R +ILE DGT  L I +A  +D G Y C A 
Sbjct: 704  VLLTCRAEGNPEPSVGWKKGLLPVSSLGPRYEILE-DGT--LRIEQAMIEDEGTYSCYAT 760

Query: 4590 NSAGEARC-DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVG 4648
            N  G  +   A   V +P T                 + P  +  V+ G+ +   C+  G
Sbjct: 761  NFKGPLQTRTANLRVVVPVTVS---------------MIPRDEHEVSVGEPLTIYCQFSG 805

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT--V 4706
            KP P  +WYK  +LI      ++S +  +  + I    P D G Y+C A +  GR    V
Sbjct: 806  KPTPFNRWYKDSQLILNGNE-RISISPGQ--ISIKSVLPSDAGLYECQAIHDYGRAADFV 862

Query: 4707 AAKLKVTQPDQA 4718
              K+K  QP  A
Sbjct: 863  TIKVKGDQPSLA 874



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 59/236 (25%), Positives = 87/236 (36%), Gaps = 16/236 (6%)

Query: 349 TSGYLAVESP-TESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGK 407
           TS Y   ++   ++Y  D ++     T  R +++     E+A   +      D D T  +
Sbjct: 541 TSDYRPTDNKEADNYTPDNQTTNNRATDNRASDDYTTNDEEANNYKTNNNAPDDDTTNHE 600

Query: 408 MTRFDCRVTGRPYPEVT--WFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
            T  D       Y +    +  ND +  D+Y      N++ NH     N T  DS     
Sbjct: 601 ATDNDAPDHNTTYYDTPDDYTTNDEEA-DNYKTN---NDTTNHEAPHHNTTDDDSPDHNT 656

Query: 466 VARNKSGETA---FQCRLNVIEKEQVVAPKFVE--RFSTLNVREGEPVVLNARAVGTPTP 520
              +   +     F C L   +K   V  +  E  R           V+L  RA G P P
Sbjct: 657 TGNDAPDDYTTNDFPCNLREADKASDVTDREAEANRAGEDPTFVRSQVLLTCRAEGNPEP 716

Query: 521 RITWQKDGVPIIP-NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
            + W+K  +P+    P   I  DG   TL I +A   D   Y C A N  G   TR
Sbjct: 717 SVGWKKGLLPVSSLGPRYEILEDG---TLRIEQAMIEDEGTYSCYATNFKGPLQTR 769



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 46/161 (28%), Positives = 60/161 (37%), Gaps = 9/161 (5%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           CR  G P P V W      +      +  + E G   L I    + D G  +C A N  G
Sbjct: 708 CRAEGNPEPSVGWKKGLLPV-SSLGPRYEILEDGT--LRIEQAMIEDEGTYSCYATNFKG 764

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
               Q R   +     V    + R     V  GEP+ +  +  G PTP   W KD   +I
Sbjct: 765 P--LQTRTANLRVVVPVTVSMIPR-DEHEVSVGEPLTIYCQFSGKPTPFNRWYKDS-QLI 820

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
            N   RI    G   + I     SDA  Y+C A +  G  A
Sbjct: 821 LNGNERISISPG--QISIKSVLPSDAGLYECQAIHDYGRAA 859



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 42/176 (23%), Positives = 74/176 (42%), Gaps = 19/176 (10%)

Query: 4423 FEHEQARFEVEFDGEPLPLIKWYRENFPIKN-SPDFQIHTFSTKSILIIRQVFVEDSAVF 4481
            F   Q       +G P P + W +   P+ +  P ++I    T   L I Q  +ED   +
Sbjct: 699  FVRSQVLLTCRAEGNPEPSVGWKKGLLPVSSLGPRYEILEDGT---LRIEQAMIEDEGTY 755

Query: 4482 AAVAEN-RGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN-VTSGQLVRLDTKVTG 4539
            +  A N +G     +ANL V          +VP + ++  ++ + V+ G+ + +  + +G
Sbjct: 756  SCYATNFKGPLQTRTANLRV----------VVPVTVSMIPRDEHEVSVGEPLTIYCQFSG 805

Query: 4540 TKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
                   W K+ + +      +I    G  +  I    P D+G YEC AI+  G A
Sbjct: 806  KPTPFNRWYKDSQLILNG-NERISISPGQIS--IKSVLPSDAGLYECQAIHDYGRA 858



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 5/84 (5%)

Query: 3839 HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAED 3898
            H V   E +   C+   K  P  R  WY++ +L+ +G+  R     G +S  I  V   D
Sbjct: 789  HEVSVGEPLTIYCQFSGKPTPFNR--WYKDSQLILNGNE-RISISPGQIS--IKSVLPSD 843

Query: 3899 SGEYICRAVNDFGEDFTKATISCK 3922
            +G Y C+A++D+G      TI  K
Sbjct: 844  AGLYECQAIHDYGRAADFVTIKVK 867



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G PTP   W +    ++  N+   R +   G +S  IK + P D G Y C A + YG A 
Sbjct: 805 GKPTPFNRWYKDSQLILNGNE---RISISPGQIS--IKSVLPSDAGLYECQAIHDYGRAA 859

Query: 157 CSVYIQPEG 165
             V I+ +G
Sbjct: 860 DFVTIKVKG 868



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 4/88 (4%)

Query: 259 SLGPVSPPKIAQKPRNS-KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
           +L  V P  ++  PR+  ++  G       Q SG P P   W+K+ Q ++N N+   I+ 
Sbjct: 772 NLRVVVPVTVSMIPRDEHEVSVGEPLTIYCQFSGKPTPFNRWYKDSQLILNGNERISISP 831

Query: 318 HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
                + +++   SD+G Y   A +  G
Sbjct: 832 GQ---ISIKSVLPSDAGLYECQAIHDYG 856



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 5/86 (5%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            ++S G+     C+    P P  R  WY + +++ +G+  R S   G   + I +V   D+
Sbjct: 790  EVSVGEPLTIYCQFSGKPTPFNR--WYKDSQLILNGNE-RISISPG--QISIKSVLPSDA 844

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKE 1940
            G Y C+AI++ G+A   + + V+  +
Sbjct: 845  GLYECQAIHDYGRAADFVTIKVKGDQ 870



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           +  GNP P V W   K  L+  +    RY E   D +L I+Q    DEG Y+C A N  G
Sbjct: 709 RAEGNPEPSVGW---KKGLLPVSSLGPRY-EILEDGTLRIEQAMIEDEGTYSCYATNFKG 764



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 4/92 (4%)

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
           + +V+ G+     C+ +G+P P   W+  D Q+  + N +I ++      + I +V  SD
Sbjct: 788 EHEVSVGEPLTIYCQFSGKPTPFNRWY-KDSQLILNGNERISISPG---QISIKSVLPSD 843

Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAP 491
           +G+  C A +  G  A    + V   +  +AP
Sbjct: 844 AGLYECQAIHDYGRAADFVTIKVKGDQPSLAP 875



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 3/61 (4%)

Query: 3593 WFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGR 3652
            W+ + + +L G+   +I+      + I  V   DAGLY C+A + +G A     ++VKG 
Sbjct: 813  WYKDSQLILNGNERISISPGQ---ISIKSVLPSDAGLYECQAIHDYGRAADFVTIKVKGD 869

Query: 3653 Q 3653
            Q
Sbjct: 870  Q 870



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 13/35 (37%), Positives = 21/35 (60%)

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            + I    P D+G Y C+A ++YG A    ++KV+G
Sbjct: 834  ISIKSVLPSDAGLYECQAIHDYGRAADFVTIKVKG 868



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 6/66 (9%)

Query: 2795 CNVEPSRDPTLKIEWFFNNKPLPS-GTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNS 2853
            C  E + +P+  + W     P+ S G RY+   D +   L I     ED G Y+C ATN 
Sbjct: 708  CRAEGNPEPS--VGWKKGLLPVSSLGPRYEILEDGT---LRIEQAMIEDEGTYSCYATNF 762

Query: 2854 KGSATT 2859
            KG   T
Sbjct: 763  KGPLQT 768


>SB_27122| Best HMM Match : I-set (HMM E-Value=1.9e-39)
          Length = 378

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 60/254 (23%), Positives = 96/254 (37%), Gaps = 30/254 (11%)

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAG------EARCDAECVVSLPATKDKPKPQTKAAN 4620
            G+ TL +L+     +G Y+C A N         +   + +C  ++    D     T    
Sbjct: 58   GSATLSLLKIQQHQAGVYQCQATNDVRRGPITHDITINVQCEYNVICYPDIFSVSTLTEQ 117

Query: 4621 APPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
             PPEI  P+++  +  G+ I  +C + G P P+V W K              ++      
Sbjct: 118  DPPEIT-PIQNTTIRAGETITLTCAVAGNPTPSVSWSKAGS----------GQSTGGNVF 166

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
              + A   D G Y C A N     T   K   T          L+   D  V E   +  
Sbjct: 167  NEAGATKADTGQYVCTAVNIVSGNT-QTKTASTYVIVKYKPSILSKSPDQTVNETTGSLK 225

Query: 4741 KTQITSKI-KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
             T I+     PT+ W R+G ++  T     ++  N+           + GT+TC AT A 
Sbjct: 226  LTCISDGYPSPTVTWSRDGVVVSRT----SVYHSNSVT-------RSEAGTYTCTATNAM 274

Query: 4800 GQVETSAKLVVKSK 4813
            G   T+ ++ V  K
Sbjct: 275  GSDTTTVQVTVNYK 288



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 50/194 (25%), Positives = 75/194 (38%), Gaps = 34/194 (17%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
           + RDV E K     C  +G P P VTW +N        +   + + +G+  L +  +   
Sbjct: 18  RSRDVAEDKDFSITCSASGHPAPNVTW-VNKT------SGSPVAHGTGSATLSLLKIQQH 70

Query: 459 DSGVVTCVARN--KSGETAF------QCRLNVIEKEQVVA--------PKFVERFSTLNV 502
            +GV  C A N  + G          QC  NVI    + +        P  +       +
Sbjct: 71  QAGVYQCQATNDVRRGPITHDITINVQCEYNVICYPDIFSVSTLTEQDPPEITPIQNTTI 130

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
           R GE + L     G PTP ++W K G               G +  +   A  +D   Y 
Sbjct: 131 RAGETITLTCAVAGNPTPSVSWSKAG----------SGQSTGGNVFNEAGATKADTGQYV 180

Query: 563 CTAQN-VAGSTATR 575
           CTA N V+G+T T+
Sbjct: 181 CTAVNIVSGNTQTK 194



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 60/223 (26%), Positives = 92/223 (41%), Gaps = 31/223 (13%)

Query: 354 AVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMT-RFD 412
           A ++ T  YV    +    +TQ +     + +  K   P  +    D+ V E   + +  
Sbjct: 171 ATKADTGQYVCTAVNIVSGNTQTKTASTYVIVKYK---PSILSKSPDQTVNETTGSLKLT 227

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C   G P P VTW       RD     ++   S  H+    +VT S++G  TC A N  G
Sbjct: 228 CISDGYPSPTVTWS------RDGV---VVSRTSVYHS---NSVTRSEAGTYTCTATNAMG 275

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN--ARAVGTPTPRITWQKDG-V 529
                 ++ V  K ++V+       ST N    +  VL+   +  G P+P+ITW K G  
Sbjct: 276 SDTTTVQVTVNYKPEMVS-------STTNTSSWDRNVLSLQCKVRGVPSPQITWYKPGDQ 328

Query: 530 PIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQNVAGS 571
           PI       +    G S L +   + A D   Y+C A N+ GS
Sbjct: 329 PITAG----VSPISGGSQLQVTTTQDAGDYGQYKCWASNLLGS 367



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 67/293 (22%), Positives = 112/293 (38%), Gaps = 44/293 (15%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP  T   QN  + +G+ + L   V G     V W K G          +  E G     
Sbjct: 119  PPEIT-PIQNTTIRAGETITLTCAVAGNPTPSVSWSKAGS--GQSTGGNVFNEAG----- 170

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
               A   D+G+Y C A+N           +VS   T+ K           P I+    D+
Sbjct: 171  ---ATKADTGQYVCTAVN-----------IVS-GNTQTKTASTYVIVKYKPSILSKSPDQ 215

Query: 4633 IVAEGQ-AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
             V E   +++ +C   G P PTV W + D ++       +SRT+  ++  ++ +   + G
Sbjct: 216  TVNETTGSLKLTCISDGYPSPTVTWSR-DGVV-------VSRTSVYHSNSVTRS---EAG 264

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
             Y C A N+ G  T   ++ V    +      ++   +   ++      + ++     P 
Sbjct: 265  TYTCTATNAMGSDTTTVQVTVNYKPE-----MVSSTTNTSSWDRNVLSLQCKVRGVPSPQ 319

Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE-DTGTFTCRATTAAGQVE 4803
            I W + G   P T     I  G+   L +  T +  D G + C A+   G VE
Sbjct: 320  ITWYKPGDQ-PITAGVSPISGGSQ--LQVTTTQDAGDYGQYKCWASNLLGSVE 369



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 46/190 (24%), Positives = 74/190 (38%), Gaps = 28/190 (14%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  +   Q+  +  G+     C V G P P V+W    +          + NE+G     
Sbjct: 119 PPEITPIQNTTIRAGETITLTCAVAGNPTPSVSW---SKAGSGQSTGGNVFNEAG----- 170

Query: 452 ITNVTLSDSGVVTCVARN-KSGETAFQCRLN--VIEKEQVVAPKFVERFSTLNVREGEPV 508
               T +D+G   C A N  SG T  +      +++ +  +  K  ++  T+N   G  +
Sbjct: 171 ---ATKADTGQYVCTAVNIVSGNTQTKTASTYVIVKYKPSILSKSPDQ--TVNETTGS-L 224

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
            L   + G P+P +TW +DGV +              S         S+A  Y CTA N 
Sbjct: 225 KLTCISDGYPSPTVTWSRDGVVV-----------SRTSVYHSNSVTRSEAGTYTCTATNA 273

Query: 569 AGSTATRARL 578
            GS  T  ++
Sbjct: 274 MGSDTTTVQV 283



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 14/118 (11%)

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
            +++GTY+C ATN  G    +V++     +   KP   +   N     D      +C V  
Sbjct: 261  SEAGTYTCTATNAMGSDTTTVQV-----TVNYKPEMVSSTTNTSSW-DRNVLSLQCKVRG 314

Query: 3176 VDDPDMKIEWYHNG-QPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231
            V  P  +I WY  G QP+  +  +  +S  G   L +  TQ+  D G+Y C A N  G
Sbjct: 315  VPSP--QITWYKPGDQPI--TAGVSPIS--GGSQLQVTTTQDAGDYGQYKCWASNLLG 366



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 16/47 (34%), Positives = 29/47 (61%)

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEK 1019
            SVT  +AG YTC A NA+G  TT+  +T+  K ++++ + +    ++
Sbjct: 257  SVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 16/31 (51%), Positives = 22/31 (70%)

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            +AG YTC ATN  GS TTT ++T + K ++V
Sbjct: 262  EAGTYTCTATNAMGSDTTTVQVTVNYKPEMV 292



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 10/108 (9%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            +   +AP F   L+    ++E +     C    +P PN  V W    K   S   + T  
Sbjct: 4    IVSTEAPAFNPPLDRSRDVAEDKDFSITCSASGHPAPN--VTWV--NKTSGSPVAHGT-- 57

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNL--GQAVSSIRLNVQSKESII 1943
              G A L +L +    +G Y C+A N++  G     I +NVQ + ++I
Sbjct: 58   --GSATLSLLKIQQHQAGVYQCQATNDVRRGPITHDITINVQCEYNVI 103



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 13/91 (14%)

Query: 1166 MYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSR 1225
            ++ +  +++  P  + P+ N   +  G+ I L C +   G+PT  V W   G   + G  
Sbjct: 108  IFSVSTLTEQDPPEITPIQNTT-IRAGETITLTCAVA--GNPTPSVSWSKAGSGQSTGGN 164

Query: 1226 FKTYYDFGFVALDIIHATSADTGEYTVRAVN 1256
               + + G        AT ADTG+Y   AVN
Sbjct: 165  --VFNEAG--------ATKADTGQYVCTAVN 185



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 14/48 (29%), Positives = 26/48 (54%)

Query: 2705 NSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDR 2752
            NS+   ++G YTC ATN +G   +T  + +  +  ++  + +  S DR
Sbjct: 256  NSVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL-KKIQELEKYER--PKP-IE 2101
            + GTY C ATNA+G   TT  V V+ K  +   T +     + +  L+   R  P P I 
Sbjct: 262  EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDRNVLSLQCKVRGVPSPQIT 321

Query: 2102 EEQPGQRPV 2110
              +PG +P+
Sbjct: 322  WYKPGDQPI 330



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 8/85 (9%)

Query: 2371 VTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHD 2430
            V+ + P F  PL    ++ E +     C     G P   V W      +  +S     H 
Sbjct: 5    VSTEAPAFNPPLDRSRDVAEDKDFSITCSAS--GHPAPNVTW------VNKTSGSPVAHG 56

Query: 2431 FGYVSMTISHVRDEDEGVYMCRASN 2455
             G  ++++  ++    GVY C+A+N
Sbjct: 57   TGSATLSLLKIQQHQAGVYQCQATN 81



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 4/83 (4%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P++     N+   +      Q ++ G P P++TW+K G + I +    I      + L+V
Sbjct: 289 PEMVSSTTNTSSWDRNVLSLQCKVRGVPSPQITWYKPGDQPITAGVSPI---SGGSQLQV 345

Query: 326 RNTQKS-DSGHYTLLAENPNGCI 347
             TQ + D G Y   A N  G +
Sbjct: 346 TTTQDAGDYGQYKCWASNLLGSV 368



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 13/42 (30%), Positives = 25/42 (59%)

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQ 1554
            ++G YTC A N +G+D  + ++T     ++V ST N +  ++
Sbjct: 262  EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/117 (21%), Positives = 49/117 (41%), Gaps = 13/117 (11%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            V V   P  +++    T      S    C  + YP P   V W  +G V+     Y +++
Sbjct: 200  VIVKYKPSILSKSPDQTVNETTGSLKLTCISDGYPSPT--VTWSRDGVVVSRTSVYHSNS 257

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEK 1954
                       V   ++G YTC A N +G   +++++ V  K  ++  + + S+ ++
Sbjct: 258  -----------VTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 14/47 (29%), Positives = 26/47 (55%)

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEK 1420
            SV   ++G YTC ATN +G   T+  + V  K +++  + + S  ++
Sbjct: 257  SVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTTNTSSWDR 303


>SB_33752| Best HMM Match : I-set (HMM E-Value=3.7e-15)
          Length = 783

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 38/119 (31%), Positives = 52/119 (43%), Gaps = 1/119 (0%)

Query: 369 QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN 428
           Q + D  + E EE  E   +   P FV    D +V EG+    D  V    Y E+ W+ N
Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKAEHY-ELEWYKN 365

Query: 429 DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
              + +    +    E G HAL+I  V   D G   CVA N +G T     L V E+E+
Sbjct: 366 AVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEE 424



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 45/149 (30%), Positives = 65/149 (43%), Gaps = 7/149 (4%)

Query: 3673 QKLEETLHKREEITIEDE-KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDW 3731
            Q LE+   + EE   E E + +PP F  E  D I+V EG  V  D  V+        ++W
Sbjct: 307  QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTD-IEVKEGENVTLDVEVKA---EHYELEW 362

Query: 3732 FHNGRPFATGSRVH-TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT-CSA 3789
            + N      G RV  T  + G  AL I+ +   D GEY C A N  G  T    +T    
Sbjct: 363  YKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEE 422

Query: 3790 KRDIVLESQLPQGMSGEKIKELERGRISD 3818
            + +   E +  +    EK+ +L +  I D
Sbjct: 423  EEESESEDETDEEFYEEKVVKLRKEHIED 451



 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 40/157 (25%), Positives = 71/157 (45%), Gaps = 7/157 (4%)

Query: 1822 QQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWY 1881
            Q LED +  +  E+ E      P          ++ EG++   +  ++     +  +EWY
Sbjct: 307  QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKA---EHYELEWY 363

Query: 1882 FNGKVLQSGHRYR-TSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
             N   +  G R R TS + G  AL I  V  +D GEY C A+N+ G+   +  L V  +E
Sbjct: 364  KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423

Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEK 1977
                +S+ E   ++  Y E   + ++   +D + +E+
Sbjct: 424  ---EESESEDETDEEFYEEKVVKLRKEHIEDFYALEE 457



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 4/134 (2%)

Query: 4501 EEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRN 4560
            EE+  +  G   PP F     ++ V  G+ V LD +V   +  ++ W KN   V    R 
Sbjct: 319  EEEESEPEGD--PPVFVHEFTDIEVKEGENVTLDVEVK-AEHYELEWYKNAVDVVEGGRV 375

Query: 4561 KILE-EDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +    E G + L+I E    D G+Y CVA+N AG   C     V+    + + + +T   
Sbjct: 376  RFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEEESESEDETDEE 435

Query: 4620 NAPPEIIEPLKDKI 4633
                ++++  K+ I
Sbjct: 436  FYEEKVVKLRKEHI 449



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 8/123 (6%)

Query: 2081 DEQRLKKIQELEKYERPKPIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPH 2140
            ++Q L+ I E E+ E     E E  G  PVF+   T +E +KEG+    +  V+     H
Sbjct: 305  EQQDLEDIAEEEEEEEE---ESEPEGDPPVFVHEFTDIE-VKEGENVTLDVEVKA---EH 357

Query: 2141 LTIDWFHNGQKIRAGHRYR-TTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTL 2199
              ++W+ N   +  G R R T+ + G  AL I     +D G Y C A N  G       L
Sbjct: 358  YELEWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNL 417

Query: 2200 KVA 2202
             VA
Sbjct: 418  TVA 420



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 36/117 (30%), Positives = 54/117 (46%), Gaps = 6/117 (5%)

Query: 3398 QTLEDSMVRRKDTSVEEE-KGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEW 3456
            Q LED     ++   E E +G  PVF    ++IE ++EGEN   +  +      + ++EW
Sbjct: 307  QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIE-VKEGENVTLDVEVKAE---HYELEW 362

Query: 3457 YWNGKSLKAGSRFR-TFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            Y N   +  G R R T  + G   L I     +D GEY C A N+ G      ++ V
Sbjct: 363  YKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV 419



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 27/110 (24%), Positives = 54/110 (49%), Gaps = 2/110 (1%)

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD-KLIKPSK 4667
            +++ + +++    PP  +    D  V EG+ +    ++  +    ++WYK    +++  +
Sbjct: 316  EEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKAEHYE-LEWYKNAVDVVEGGR 374

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
                S    ++ L I E   +D+G+Y CVA N AGR T A  L V + ++
Sbjct: 375  VRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEE 424



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 5/110 (4%)

Query: 3270 QQQTPSTPSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGH 3329
            +++  S P  +PP F+ +  D+ ++ EG++   +   V V     ++EW+ N   +  G 
Sbjct: 318  EEEEESEPEGDPPVFVHEFTDI-EVKEGENVTLD---VEVKAEHYELEWYKNAVDVVEGG 373

Query: 3330 RYR-TFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKANLKCTSKE 3378
            R R T  + G   L I    +++ GEY CVA N  GR +   NL    +E
Sbjct: 374  RVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 5/111 (4%)

Query: 2481 PEGMKKIQKLEQPHERRSEEPDREFEKPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSL 2540
            P   + ++ + +  E   EE + E + P+F    T   E+ EG++   +   V V     
Sbjct: 303  PGEQQDLEDIAEEEEEEEEESEPEGDPPVFVHEFTD-IEVKEGENVTLD---VEVKAEHY 358

Query: 2541 RFEWYINGVELKMGSRFR-TTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
              EWY N V++  G R R T+ + G   L I  V  +D G Y C A+N AG
Sbjct: 359  ELEWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAG 409



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 40/154 (25%), Positives = 63/154 (40%), Gaps = 6/154 (3%)

Query: 1021 QYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWY 1080
            Q LED +   +  EEE +    P          ++ EG++   +  V+ +      +EWY
Sbjct: 307  QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKAEH---YELEWY 363

Query: 1081 FNGKQITSANRIQ-TYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTV--ET 1137
             N   +    R++ T  + G  AL I  V  +D G Y  VA N AG    + ++TV  E 
Sbjct: 364  KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423

Query: 1138 RSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEE 1171
              S          YE+       + +E  Y +EE
Sbjct: 424  EESESEDETDEEFYEEKVVKLRKEHIEDFYALEE 457



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/126 (25%), Positives = 51/126 (40%), Gaps = 2/126 (1%)

Query: 4382 ITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPL 4441
            I   E  ++E  A+ +E   E       PP+F  +     V E E    +VE   E   L
Sbjct: 301  IVPGEQQDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKAEHYEL 360

Query: 4442 IKWYRENFPIKNSPDFQIHT-FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVV 4500
             +WY+    +      +  +    K  L+I +V  +D   +  VA N  G   C+ NL V
Sbjct: 361  -EWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV 419

Query: 4501 EEKRRQ 4506
             E+  +
Sbjct: 420  AEEEEE 425



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 5/121 (4%)

Query: 2617 EQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKI 2676
            EQ  L++ A  +  E          P+F       + + EG++V L+ +V+     + ++
Sbjct: 305  EQQDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIE-VKEGENVTLDVEVKAE---HYEL 360

Query: 2677 EWFKNGVTLTTGARLKSTF-DFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
            EW+KN V +  G R++ T  + G   L I  + +DD G Y C A N  G      ++ + 
Sbjct: 361  EWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVA 420

Query: 2736 D 2736
            +
Sbjct: 421  E 421



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 2/89 (2%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHT-DGGASTLD 549
           P FV  F+ + V+EGE V L+   V      + W K+ V ++    +R  + +GG   L 
Sbjct: 330 PVFVHEFTDIEVKEGENVTLDVE-VKAEHYELEWYKNAVDVVEGGRVRFTSGEGGKHALV 388

Query: 550 IPRAKASDAAWYQCTAQNVAGSTATRARL 578
           I   +  D   Y C A N AG T     L
Sbjct: 389 IEEVEDDDQGEYCCVAMNDAGRTTCAGNL 417



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 5/107 (4%)

Query: 3806 EKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEW 3865
            + ++++      +  + EP    PP F+ +     V+E E V  +  V+ +      +EW
Sbjct: 307  QDLEDIAEEEEEEEEESEP-EGDPPVFVHEFTDIEVKEGENVTLDVEVKAEH---YELEW 362

Query: 3866 YRNGKLLPSGHRYR-TVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            Y+N   +  G R R T  + G  +L I  V  +D GEY C A+ND G
Sbjct: 363  YKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAG 409



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 37/147 (25%), Positives = 64/147 (43%), Gaps = 6/147 (4%)

Query: 1691 LEDTSKYQRHSAQD-EVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRN 1749
            LED ++ +    ++ E     PVF     DI V E +    +   + V      +EW +N
Sbjct: 309  LEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLD---VEVKAEHYELEWYKN 365

Query: 1750 GVPIEASNRLT-TMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
             V +    R+  T  + G  AL ++ V  +D G Y C A+N+ G    +  L V  +   
Sbjct: 366  AVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEE- 424

Query: 1809 QLESQHESALQKIQQLEDSSRYQRRED 1835
            + ES+ E+  +  ++     R +  ED
Sbjct: 425  ESESEDETDEEFYEEKVVKLRKEHIED 451



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 6/138 (4%)

Query: 748 QQLEDYSKYQHQESIE-EQTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEW 806
           Q LED ++ + +E  E E     P F+    D+ E++EG N   + +   V      +EW
Sbjct: 307 QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDI-EVKEGENVTLDVE---VKAEHYELEW 362

Query: 807 YKDGRPITASSRIT-SIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRVAAR 865
           YK+   +    R+  +    G  +L I  +  +D G Y   A+N  G      ++ VA  
Sbjct: 363 YKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEE 422

Query: 866 STVTADLGIPEQRRYIEK 883
              +      ++  Y EK
Sbjct: 423 EEESESEDETDEEFYEEK 440



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 4/90 (4%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTH-DFSYVSL 2833
            VF+    +I  KEG+N+  +  V+       ++EW+ N   +  G R + T  +    +L
Sbjct: 331  VFVHEFTDIEVKEGENVTLDVEVKAEH---YELEWYKNAVDVVEGGRVRFTSGEGGKHAL 387

Query: 2834 DITHTYEEDSGIYTCKATNSKGSATTSGSL 2863
             I    ++D G Y C A N  G  T +G+L
Sbjct: 388  VIEEVEDDDQGEYCCVAMNDAGRTTCAGNL 417



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 8/151 (5%)

Query: 1289 QLLEDAARRTKQVREDITVM-QAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWF 1347
            Q LED A   ++  E+       P F     +IE  EG NV L+  ++    +   +EW+
Sbjct: 307  QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKA---EHYELEWY 363

Query: 1348 CNGKPIKTGHRFR-PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKK 1406
             N   +  G R R  + E    AL +  V  +D G Y C A N  G    +  L V  ++
Sbjct: 364  KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423

Query: 1407 DLILESQHPSGLEKIQYLEDTSRYKKTDIID 1437
            +   ES+     ++  Y E   + +K  I D
Sbjct: 424  E---ESESEDETDEEFYEEKVVKLRKEHIED 451



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 2/91 (2%)

Query: 68  EPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTG 127
           E  PP+F   F +    +G N   + +++     +  W +    +VE  +      E  G
Sbjct: 326 EGDPPVFVHEFTDIEVKEGENVTLDVEVKAEHYEL-EWYKNAVDVVEGGRVRFTSGEG-G 383

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICS 158
             +L+I+++   D+GEY C A N  G   C+
Sbjct: 384 KHALVIEEVEDDDQGEYCCVAMNDAGRTTCA 414



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 6/114 (5%)

Query: 2233 EVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFH 2292
            E  EP+  PP FV E      V EG+    + +V+  H     +E+Y N   +    R  
Sbjct: 321  EESEPEGDPPVFVHEFTDI-EVKEGENVTLDVEVKAEH---YELEWYKNAVDVVEGGRVR 376

Query: 2293 ITF-DFGYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQ 2345
             T  + G  +L I+    +D GEY   A+N  G  T A ++TV A+    SES+
Sbjct: 377  FTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV-AEEEEESESE 429



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 43/169 (25%), Positives = 69/169 (40%), Gaps = 12/169 (7%)

Query: 904  ESTQKPEFKTPIK----DQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRIT 959
            E   +PE   P+       I +KEG     +  ++        +EW K+   V    R+ 
Sbjct: 320  EEESEPEGDPPVFVHEFTDIEVKEGENVTLDVEVKA---EHYELEWYKNAVDVVEGGRVR 376

Query: 960  -TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLE 1018
             T    G  AL I+ V   D G Y C A N  G+ T + NLT+  +++   ES+     +
Sbjct: 377  FTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEEE---ESESEDETD 433

Query: 1019 KIQYLEDASRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSA-HFEAR 1066
            +  Y E   +  K   E+    ++    G      K V  ++A HF A+
Sbjct: 434  EEFYEEKVVKLRKEHIEDFYALEEEVGRGRFGVVRKCVHLKTAVHFVAK 482



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 45/184 (24%), Positives = 72/184 (39%), Gaps = 10/184 (5%)

Query: 1556 QVLEDRSKYHRTDMVD-EVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWY 1614
            Q LED ++    +  + E     P+      ++E+KEG+    +   + V     ++EWY
Sbjct: 307  QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLD---VEVKAEHYELEWY 363

Query: 1615 HNNKPLKSGSRFTETNNFGFV-ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKK 1673
             N   +  G R   T+  G   AL I     +D G Y C A+N  G    +G   V  ++
Sbjct: 364  KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTVAEEE 423

Query: 1674 SIYLESQHEGALPRLNQLEDTSKYQRHSAQDEVITQAPVFTMPMKDIR--VAENQAAHFE 1731
                ES+ E         E   K ++   +D    +  V       +R  V    A HF 
Sbjct: 424  E---ESESEDETDEEFYEEKVVKLRKEHIEDFYALEEEVGRGRFGVVRKCVHLKTAVHFV 480

Query: 1732 ARLI 1735
            A+ I
Sbjct: 481  AKSI 484



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 10/112 (8%)

Query: 2348 EGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPT 2407
            + LE I E E  E  +     +P     PVF     +I+ ++EG+    D   + V    
Sbjct: 307  QDLEDIAEEEEEEEEESEPEGDP-----PVFVHEFTDIE-VKEGENVTLD---VEVKAEH 357

Query: 2408 LKVEWFRNEKLIEDSSRITKTH-DFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
             ++EW++N   + +  R+  T  + G  ++ I  V D+D+G Y C A N  G
Sbjct: 358  YELEWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAG 409



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 3555 GNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVK-TINDFG 3613
            G+PP F    +D+ + E  +   +   + V      +EW+ N   ++ G RV+ T  + G
Sbjct: 327  GDPPVFVHEFTDIEVKEGENVTLD---VEVKAEHYELEWYKNAVDVVEGGRVRFTSGEGG 383

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
               L I  V   D G Y C A N  G  T +  L V
Sbjct: 384  KHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV 419



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 34/116 (29%), Positives = 50/116 (43%), Gaps = 5/116 (4%)

Query: 1956 QYLEDDSRYKRAVQDDSFVV-EKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWY 2014
            Q LED +  +   +++S    + P F     + EV EG  V L+     V      +EWY
Sbjct: 307  QDLEDIAEEEEEEEEESEPEGDPPVFVHEFTDIEVKEGENVTLDVE---VKAEHYELEWY 363

Query: 2015 CNGRPVQQGHRFK-TTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             N   V +G R + T+ + G  AL I     +D G Y C A N  G      ++ V
Sbjct: 364  KNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLTV 419



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 5/101 (4%)

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
            AE   + E   + +G  P F     +IE +K+G++   +   V V     ++EWY N   
Sbjct: 313  AEEEEEEEEESEPEGDPPVFVHEFTDIE-VKEGENVTLD---VEVKAEHYELEWYKNAVD 368

Query: 3192 MRHSTRIK-TVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
            +    R++ T  + G   L I   ++ D GEY C A N  G
Sbjct: 369  VVEGGRVRFTSGEGGKHALVIEEVEDDDQGEYCCVAMNDAG 409



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFR-PIHDFGYV 1502
            P FV     IE V EG++V  + +++     + ++EW+KN   V  G R R    + G  
Sbjct: 330  PVFVHEFTDIE-VKEGENVTLDVEVKA---EHYELEWYKNAVDVVEGGRVRFTSGEGGKH 385

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
            AL I ++  +D G Y C A+N  G    +  LT
Sbjct: 386  ALVIEEVEDDDQGEYCCVAMNDAGRTTCAGNLT 418



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 2922 QLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFKLTS-DFGFVTLDLVDVYERD 2980
            ++ EG+ + L+ +V+ ++    ++EWY N   + +G R + TS + G   L + +V + D
Sbjct: 340  EVKEGENVTLDVEVKAEH---YELEWYKNAVDVVEGGRVRFTSGEGGKHALVIEEVEDDD 396

Query: 2981 SGIYTCKAYNKRG 2993
             G Y C A N  G
Sbjct: 397  QGEYCCVAMNDAG 409


>SB_9092| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 662

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 50/174 (28%), Positives = 73/174 (41%), Gaps = 7/174 (4%)

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            +G AI     + G P PTV W KG+  + P    + S   ++++LRIS   P+DEG+Y  
Sbjct: 123  DGDAI-IKVDVDGFPKPTVVWKKGNGELIPIVNDRYS-VLEDFSLRISGMTPKDEGNYIF 180

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
                +A       K     P +    P   P++  V   G    F   +T   KPT+QW+
Sbjct: 181  EVTQAALFRPFTIKAIAFSPPEIIQQP--VPIKRYVTV-GYNTSFTCIVTGFPKPTVQWI 237

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809
              G    E   F   +E       I N    D G +TCR T     +E  A ++
Sbjct: 238  NPGG--REVDTFDPRYEIIGDTFYIYNIESNDKGNWTCRVTGGDVTIEAVATII 289



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 44/187 (23%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            +  G  P  V  LK G+ + P  R K+     +    +L  +  D G Y C A   A ++
Sbjct: 319  RANGKPPPTVVILKAGR-IHP--RMKMRPGAASIEFYLLREH--DLGNYTCEAWGPARDS 373

Query: 4596 RCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQ 4655
            +     V    A   + KP      +P EI        V   Q +  +C  +  PL  V 
Sbjct: 374  QGMPVVVNQSVALYTRDKPVINPGGSPKEIFS-----YVGNTQPVRINCDFISWPLANVT 428

Query: 4656 WYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK-VTQ 4714
             ++G        +++++   D+ TL +     ED G Y C+  N  G V     ++  T 
Sbjct: 429  IWRG--------FYELTNGTDQATLYVWTYAWEDFGPYSCIGSNMFGEVNYTVWIRHATP 480

Query: 4715 PDQADNL 4721
            P + +N+
Sbjct: 481  PSKPENI 487



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 75/301 (24%), Positives = 115/301 (38%), Gaps = 44/301 (14%)

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLD------TKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            RG      F L   ++ V + Q +R+D        V G     V W K   ++ P + ++
Sbjct: 97   RGNTGNKIFLLWVTHIKVNTTQYLRIDGDAIIKVDVDGFPKPTVVWKKGNGELIPIVNDR 156

Query: 4562 --ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
              +LE+   ++L I    P+D G Y    +  A   R               P      A
Sbjct: 157  YSVLED---FSLRISGMTPKDEGNY-IFEVTQAALFR---------------PFTIKAIA 197

Query: 4620 NAPPEIIE---PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTA 4675
             +PPEII+   P+K + V  G    F+C + G P PTVQW   G + +     F      
Sbjct: 198  FSPPEIIQQPVPIK-RYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDT---FDPRYEI 253

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE- 4734
               T  I      D+G++ C    + G VT+ A   +     A  L A      +  +E 
Sbjct: 254  IGDTFYIYNIESNDKGNWTCRV--TGGDVTIEAVATIIDVYTAP-LVAEPSFPWVYWFEL 310

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
             +PA    +   K  PT+  L+ G + P     +M      A +      E D G +TC 
Sbjct: 311  YRPASITCRANGKPPPTVVILKAGRIHP-----RMKMRPGAASIEFYLLREHDLGNYTCE 365

Query: 4795 A 4795
            A
Sbjct: 366  A 366



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 47/167 (28%), Positives = 67/167 (40%), Gaps = 14/167 (8%)

Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
           R VT G  T F C VTG P P V W     +  D ++ +    E       I N+  +D 
Sbjct: 212 RYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRY---EIIGDTFYIYNIESNDK 268

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE-RFSTLNVRE-GEPVVLNARAVGTP 518
           G  TC  R   G+   +    +I  +   AP   E  F  +   E   P  +  RA G P
Sbjct: 269 GNWTC--RVTGGDVTIEAVATII--DVYTAPLVAEPSFPWVYWFELYRPASITCRANGKP 324

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
            P +   K G  I P  ++R     GA++++    +  D   Y C A
Sbjct: 325 PPTVVILKAG-RIHPRMKMR----PGAASIEFYLLREHDLGNYTCEA 366



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 16/98 (16%)

Query: 264 SPPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS--NKHEIITTHN 319
           SPP+I Q+P   K  +  G +  F   ++G P+P V W   G R +++   ++EII    
Sbjct: 199 SPPEIIQQPVPIKRYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEII---- 254

Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
             T  + N + +D G++T        C VT G + +E+
Sbjct: 255 GDTFYIYNIESNDKGNWT--------CRVTGGDVTIEA 284



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 4110 PPVFVSLPDAVT--VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN--GSRYKLTYDGMY 4165
            PP  +  P  +   V  G    F C VTG PKP V W+  G   V+    RY++  D  Y
Sbjct: 200  PPEIIQQPVPIKRYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEIIGDTFY 259

Query: 4166 HFDI 4169
             ++I
Sbjct: 260  IYNI 263



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 14/129 (10%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVT 464
           G   R DC V+G    E  +     ++ D    +I  + +G+ + L + N+T+ D G  T
Sbjct: 36  GASLRVDCTVSGGETFEGWFSPGGARVSDQEIERIHSDRNGDRYTLHVNNITVQDGGQYT 95

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C  R  +G   F   +  I+             +T  +R     ++     G P P + W
Sbjct: 96  C--RGNTGNKIFLLWVTHIKVN-----------TTQYLRIDGDAIIKVDVDGFPKPTVVW 142

Query: 525 QKDGVPIIP 533
           +K    +IP
Sbjct: 143 KKGNGELIP 151


>SB_3191| Best HMM Match : ig (HMM E-Value=3.5e-16)
          Length = 326

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 49/174 (28%), Positives = 73/174 (41%), Gaps = 7/174 (4%)

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            +G AI     + G P PTV W KG+  + P    + +   ++++LRIS   P+DEG+Y  
Sbjct: 103  DGDAI-IKVDVDGFPKPTVVWKKGNGELIPIVNDRYT-VLEDFSLRISGMTPKDEGNYIF 160

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL 4755
                +A       K     P +    P   P++  V   G    F   +T   KPT+QW+
Sbjct: 161  EVTQAALFRPFTIKAIAFSPPEIIQQP--VPIKRYVTL-GYNTSFTCIVTGFPKPTVQWI 217

Query: 4756 REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809
              G    E   F   +E       I N    D G +TCR T     +E  A ++
Sbjct: 218  NPGG--REVDTFDPRYEIIGDTFYIYNIESNDKGNWTCRVTGGDVTIEAVATII 269



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 16/98 (16%)

Query: 264 SPPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS--NKHEIITTHN 319
           SPP+I Q+P   K  +  G +  F   ++G P+P V W   G R +++   ++EII    
Sbjct: 179 SPPEIIQQPVPIKRYVTLGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEII---- 234

Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
             T  + N + +D G++T        C VT G + +E+
Sbjct: 235 GDTFYIYNIESNDKGNWT--------CRVTGGDVTIEA 264



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 44/160 (27%), Positives = 66/160 (41%), Gaps = 31/160 (19%)

Query: 4508 RGGIVPPSFTLTAQNVNVTSGQLVRLD------TKVTGTKPIDVYWLKNGKKVQPDIRNK 4561
            RG      F L   ++ V + Q +R+D        V G     V W K   ++ P + ++
Sbjct: 77   RGNTGNKIFLLWVTHIKVNTTQYLRIDGDAIIKVDVDGFPKPTVVWKKGNGELIPIVNDR 136

Query: 4562 --ILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
              +LE+   ++L I    P+D G Y    +  A   R               P      A
Sbjct: 137  YTVLED---FSLRISGMTPKDEGNY-IFEVTQAALFR---------------PFTIKAIA 177

Query: 4620 NAPPEIIE---PLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
             +PPEII+   P+K + V  G    F+C + G P PTVQW
Sbjct: 178  FSPPEIIQQPVPIK-RYVTLGYNTSFTCIVTGFPKPTVQW 216



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 4110 PPVFVSLPDAVT--VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN--GSRYKLTYDGMY 4165
            PP  +  P  +   V  G    F C VTG PKP V W+  G   V+    RY++  D  Y
Sbjct: 180  PPEIIQQPVPIKRYVTLGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEIIGDTFY 239

Query: 4166 HFDI 4169
             ++I
Sbjct: 240  IYNI 243



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 30/129 (23%), Positives = 51/129 (39%), Gaps = 14/129 (10%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVT 464
           G   R DC V+G    E  +     ++ D    +I  + +G+ + L + N+T  D G  T
Sbjct: 16  GASLRVDCTVSGGETFEGWFSPGGARVSDQEIERIHSDRNGDRYTLHVNNITAQDGGQYT 75

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C  R  +G   F   +  I+             +T  +R     ++     G P P + W
Sbjct: 76  C--RGNTGNKIFLLWVTHIKVN-----------TTQYLRIDGDAIIKVDVDGFPKPTVVW 122

Query: 525 QKDGVPIIP 533
           +K    +IP
Sbjct: 123 KKGNGELIP 131



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 5/84 (5%)

Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
           R VT G  T F C VTG P P V W     +  D ++ +    E       I N+  +D 
Sbjct: 192 RYVTLGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRY---EIIGDTFYIYNIESNDK 248

Query: 461 GVVTCVARNKSGETAFQCRLNVIE 484
           G  TC  R   G+   +    +I+
Sbjct: 249 GNWTC--RVTGGDVTIEAVATIID 270


>SB_41624| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 917

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 59/209 (28%), Positives = 88/209 (42%), Gaps = 25/209 (11%)

Query: 4553 KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP 4612
            +VQ  I   I+E      L I +A   D+G Y C        A  +A  VV +   KD  
Sbjct: 538  RVQQSIDGNIIET----VLKIRDATTSDAGNYTCTLEGPGPSALDNATAVVDV---KDLS 590

Query: 4613 KPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMS 4672
             P   A + P ++        V E  + E +C +   P PTV W K  +   P +Y  +S
Sbjct: 591  HPLI-AMSTPTKLT-------VNETSSFELTCVVTASPGPTVTWTKSAE--DPKRY-SVS 639

Query: 4673 RTADEYTLRI-SEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNL--PALTPLRD 4729
             +   YTLR+ S  +P+D G + C A N+ G  T +  + V +      L  P +    D
Sbjct: 640  HSNGRYTLRVTSSVYPDDAGKFICRAENAEGFSTKSVIVNVHECLSLSRLAKPIIEKKED 699

Query: 4730 IVVYEGQPAQFKTQI----TSKIKPTIQW 4754
              V   +P++F        +S   P IQW
Sbjct: 700  TRVIVAKPSEFVRMACPIKSSNPPPMIQW 728



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/125 (24%), Positives = 49/125 (39%), Gaps = 4/125 (3%)

Query: 4677 EYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQ 4736
            E  L+I +A   D G+Y C            A   V   D +  L A++    + V E  
Sbjct: 549  ETVLKIRDATTSDAGNYTCTLEGPGPSALDNATAVVDVKDLSHPLIAMSTPTKLTVNETS 608

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRA 4795
              +    +T+   PT+ W +      +   + + H  G   + +  + Y +D G F CRA
Sbjct: 609  SFELTCVVTASPGPTVTWTKSA---EDPKRYSVSHSNGRYTLRVTSSVYPDDAGKFICRA 665

Query: 4796 TTAAG 4800
              A G
Sbjct: 666  ENAEG 670



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 5/98 (5%)

Query: 3967 VDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIY 4026
            VD K     +  + + T L   ET+ FE        P   V W    K      R++  +
Sbjct: 584  VDVKDLSHPLIAMSTPTKLTVNETSSFELTCVVTASPGPTVTWT---KSAEDPKRYSVSH 640

Query: 4027 DFG-YVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
              G Y       VYP+D+G+++CRA N  G   TK+VI
Sbjct: 641  SNGRYTLRVTSSVYPDDAGKFICRAENAEGF-STKSVI 677



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 4/96 (4%)

Query: 1850 LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILT- 1908
            ++ PTKL+  +++ +E        P   V W    K  +   RY  S+  G   L + + 
Sbjct: 596  MSTPTKLTVNETSSFELTCVVTASPGPTVTWT---KSAEDPKRYSVSHSNGRYTLRVTSS 652

Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIR 1944
            VY +D+G++ C+A N  G +  S+ +NV    S+ R
Sbjct: 653  VYPDDAGKFICRAENAEGFSTKSVIVNVHECLSLSR 688



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 37/136 (27%), Positives = 54/136 (39%), Gaps = 7/136 (5%)

Query: 3424 VPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEI- 3482
            + +S    L   E + FE     T  P   V W    KS +   R+      G   L + 
Sbjct: 594  IAMSTPTKLTVNETSSFELTCVVTASPGPTVTWT---KSAEDPKRYSVSHSNGRYTLRVT 650

Query: 3483 SPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYS 3542
            S  YP+D+G+++CRA N   E  +T S+ V     + L       +E   D    +   S
Sbjct: 651  SSVYPDDAGKFICRAEN--AEGFSTKSVIVNVHECLSLSRLAKPIIEKKEDTRVIVAKPS 708

Query: 3543 GTVDTLTPEAESGNPP 3558
              V    P  +S NPP
Sbjct: 709  EFVRMACP-IKSSNPP 723



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 38/153 (24%), Positives = 55/153 (35%), Gaps = 9/153 (5%)

Query: 424 TWFINDR--QIRDDYNHKILVNESGN---HALMITNVTLSDSGVVTCVARNKSGETAFQC 478
           TW   D     R   N ++  +  GN     L I + T SD+G  TC      G +A   
Sbjct: 521 TWTQTDHTGHTRTVSNDRVQQSIDGNIIETVLKIRDATTSDAGNYTCTLEGP-GPSALDN 579

Query: 479 RLNVIEKEQVVAPKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
              V++ + +  P       T L V E     L      +P P +TW K      P    
Sbjct: 580 ATAVVDVKDLSHPLIAMSTPTKLTVNETSSFELTCVVTASPGPTVTWTKSAED--PKRYS 637

Query: 538 RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             H++G  +          DA  + C A+N  G
Sbjct: 638 VSHSNGRYTLRVTSSVYPDDAGKFICRAENAEG 670



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 7/137 (5%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            VL+I    T+D+G Y+C      G + +      VD      P     +     L   ++
Sbjct: 551  VLKIRDATTSDAGNYTCTLEGP-GPSALDNATAVVDVKDLSHPLIA--MSTPTKLTVNET 607

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQ-PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
            + FE T V    P   + W  + + P R+S    + S+  + +   +     D+G+++CR
Sbjct: 608  SSFELTCVVTASPGPTVTWTKSAEDPKRYSV---SHSNGRYTLRVTSSVYPDDAGKFICR 664

Query: 3226 AYNKYGEDFTRATINCY 3242
            A N  G       +N +
Sbjct: 665  AENAEGFSTKSVIVNVH 681



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 6/87 (6%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            + +S    +   E  +    C V  S  PT  + W    K      RY  +H     +L 
Sbjct: 594  IAMSTPTKLTVNETSSFELTCVVTASPGPT--VTW---TKSAEDPKRYSVSHSNGRYTLR 648

Query: 2835 ITHT-YEEDSGIYTCKATNSKGSATTS 2860
            +T + Y +D+G + C+A N++G +T S
Sbjct: 649  VTSSVYPDDAGKFICRAENAEGFSTKS 675



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 4/89 (4%)

Query: 1721 RVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNM-KYVNPED 1779
            ++  N+ + FE   +    P   V W ++    E   R +  H  G   L +   V P+D
Sbjct: 601  KLTVNETSSFELTCVVTASPGPTVTWTKSA---EDPKRYSVSHSNGRYTLRVTSSVYPDD 657

Query: 1780 SGTYTCRAINELGEAVTSSTLFVQSKASL 1808
            +G + CRA N  G +  S  + V    SL
Sbjct: 658  AGKFICRAENAEGFSTKSVIVNVHECLSL 686



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 5/110 (4%)

Query: 1567 TDMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF 1626
            T +VD      P+   S    ++   + + FE   +  +     V W    K  +   R+
Sbjct: 581  TAVVDVKDLSHPLIAMSTPT-KLTVNETSSFELTCVVTASPGPTVTW---TKSAEDPKRY 636

Query: 1627 TETNNFGFVALDIMSCL-PEDSGTYTCRAINALGEAVTSGIAIVHSKKSI 1675
            + +++ G   L + S + P+D+G + CRA NA G +  S I  VH   S+
Sbjct: 637  SVSHSNGRYTLRVTSSVYPDDAGKFICRAENAEGFSTKSVIVNVHECLSL 686



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 2392 QTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG-YVSMTISHVRDEDEGVYM 2450
            +T+ F+   +    P   V W    K  ED  R + +H  G Y     S V  +D G ++
Sbjct: 606  ETSSFELTCVVTASPGPTVTW---TKSAEDPKRYSVSHSNGRYTLRVTSSVYPDDAGKFI 662

Query: 2451 CRASNLLG 2458
            CRA N  G
Sbjct: 663  CRAENAEG 670



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 5/85 (5%)

Query: 263 VSPPKIAQK-PRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           +S P IA   P    + E +  +    ++ +P P VTW K+ +   +  ++ +  ++   
Sbjct: 589 LSHPLIAMSTPTKLTVNETSSFELTCVVTASPGPTVTWTKSAE---DPKRYSVSHSNGRY 645

Query: 322 TLRVRNT-QKSDSGHYTLLAENPNG 345
           TLRV ++    D+G +   AEN  G
Sbjct: 646 TLRVTSSVYPDDAGKFICRAENAEG 670



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 2514 LTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDI-NS 2572
            ++ P++L   + + +E   V    P     W  +  + K   R+  +H  G  TL + +S
Sbjct: 596  MSTPTKLTVNETSSFELTCVVTASPGPTVTWTKSAEDPK---RYSVSHSNGRYTLRVTSS 652

Query: 2573 VVANDAGLYMCKAINRAG 2590
            V  +DAG ++C+A N  G
Sbjct: 653  VYPDDAGKFICRAENAEG 670



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/91 (23%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 2112 LTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDI 2171
            L A+++   L   + + FE        P  T+ W  + +  +   RY  +H  G   L +
Sbjct: 593  LIAMSTPTKLTVNETSSFELTCVVTASPGPTVTWTKSAEDPK---RYSVSHSNGRYTLRV 649

Query: 2172 LYT-YAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              + Y +D+G ++C+A N  G +  +  + V
Sbjct: 650  TSSVYPDDAGKFICRAENAEGFSTKSVIVNV 680



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 5/83 (6%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT-NVTLSDSG 461
           V E       C VT  P P VTW     +  +D     + + +G + L +T +V   D+G
Sbjct: 604 VNETSSFELTCVVTASPGPTVTW----TKSAEDPKRYSVSHSNGRYTLRVTSSVYPDDAG 659

Query: 462 VVTCVARNKSGETAFQCRLNVIE 484
              C A N  G +     +NV E
Sbjct: 660 KFICRAENAEGFSTKSVIVNVHE 682



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 25/104 (24%), Positives = 45/104 (43%), Gaps = 6/104 (5%)

Query: 1988 EVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYA-YAED 2046
            ++T       E T      P   V W    +  +   R+  ++  G   L +  + Y +D
Sbjct: 601  KLTVNETSSFELTCVVTASPGPTVTWT---KSAEDPKRYSVSHSNGRYTLRVTSSVYPDD 657

Query: 2047 TGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQE 2090
             G ++C+A NA  E  +T SV V+    L L  L +  ++K ++
Sbjct: 658  AGKFICRAENA--EGFSTKSVIVNVHECLSLSRLAKPIIEKKED 699


>SB_13651| Best HMM Match : I-set (HMM E-Value=4e-17)
          Length = 333

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 23/188 (12%)

Query: 390 LAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           +AP F   +    DV E       C  +GRP P VTW +N        +   + + +G+ 
Sbjct: 157 VAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPNVTW-VNKT------SGSPVAHGTGSA 209

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508
            L +  +    +G+  C A N  G  A    + +I    V  P  +       VR GE +
Sbjct: 210 TLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTII----VQYPPEITPIQNTTVRAGETI 265

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN- 567
            L     G PTP ++W K G           H+ GG         KA     Y CTA N 
Sbjct: 266 TLTCAVAGNPTPSVSWSKAGSG---------HSTGGNVFTKAGATKAV-TGQYVCTAVNT 315

Query: 568 VAGSTATR 575
           V G+T TR
Sbjct: 316 VTGNTQTR 323



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 40/148 (27%), Positives = 63/148 (42%), Gaps = 22/148 (14%)

Query: 4512 VPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            V P+FT + + +++V     V      +G    +V W+ N     P     +    G+ T
Sbjct: 157  VAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPNVTWV-NKTSGSP-----VAHGTGSAT 210

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L +L+     +G Y+C AIN  G              T+D     T     PPEI  P++
Sbjct: 211  LSLLKIQRHQAGLYQCQAINDVGRGAI----------TQDV----TIIVQYPPEIT-PIQ 255

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            +  V  G+ I  +C + G P P+V W K
Sbjct: 256  NTTVRAGETITLTCAVAGNPTPSVSWSK 283



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 26/126 (20%), Positives = 49/126 (38%), Gaps = 10/126 (7%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            VAE   +  +C   G+P P V W      +  +    ++      TL + +      G Y
Sbjct: 171  VAENDDVTNTCSASGRPAPNVTW------VNKTSGSPVAHGTGSATLSLLKIQRHQAGLY 224

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
            +C A N  GR  +   + +         P +TP+++  V  G+       +     P++ 
Sbjct: 225  QCQAINDVGRGAITQDVTII----VQYPPEITPIQNTTVRAGETITLTCAVAGNPTPSVS 280

Query: 4754 WLREGA 4759
            W + G+
Sbjct: 281  WSKAGS 286



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 8/105 (7%)

Query: 2630 PEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA 2689
            P    D  V+ AP FT+ L S   + E   V        R  PN  + W    V  T+G+
Sbjct: 147  PSASWDLNVKVAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPN--VTW----VNKTSGS 200

Query: 2690 RLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +      G  TLS+  ++   +G+Y C+A N +G    T  + I
Sbjct: 201  PV--AHGTGSATLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTI 243



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 39/151 (25%), Positives = 61/151 (40%), Gaps = 12/151 (7%)

Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDV 1836
            P D+ T     +   G+  + S +     AS+  E  +   L KI+    SS        
Sbjct: 96   PNDTDTIYKGRVYFYGDFTSCSGVVEIRNASVVHEKPY---LVKIRT-SSSSPLSPSASW 151

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V  AP F + L+    ++E       C     P PN  V W    K   S   + T 
Sbjct: 152  DLNVKVAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPN--VTWV--NKTSGSPVAHGT- 206

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
               G A L +L +    +G Y C+AIN++G+
Sbjct: 207  ---GSATLSLLKIQRHQAGLYQCQAINDVGR 234



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 15/134 (11%)

Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEAT 2000
            S+++  +H++ L + Q + D  R     QD + +V+ P    PI+N  V  G  + L  T
Sbjct: 212  SLLKIQRHQAGLYQCQAINDVGR-GAITQDVTIIVQYPPEITPIQNTTVRAGETITL--T 268

Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV-G 2059
                 +PT  V W   G     GH        G        A    TG Y+C A N V G
Sbjct: 269  CAVAGNPTPSVSWSKAG----SGH------STGGNVFTKAGATKAVTGQYVCTAVNTVTG 318

Query: 2060 EAVT-TSSVKVDAK 2072
               T T+S  V  K
Sbjct: 319  NTQTRTASTYVMVK 332



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 45/195 (23%), Positives = 71/195 (36%), Gaps = 25/195 (12%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P FT+     +D++E        S   +G  +  + W         +H        G   
Sbjct: 159  PAFTSSLSSSLDVAENDDVTNTCSA--SGRPAPNVTWVNKTSGSPVAH------GTGSAT 210

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L +L  +   +G Y C+A N  G+  I+  +  +     Q P   T IQN   ++ G++ 
Sbjct: 211  LSLLKIQRHQAGLYQCQAINDVGRGAITQDVTII----VQYPPEITPIQNTT-VRAGETI 265

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C V    +P   + W   G    HST        G  V   A      +G+YVC A 
Sbjct: 266  TLTCAV--AGNPTPSVSWSKAGS--GHST--------GGNVFTKAGATKAVTGQYVCTAV 313

Query: 3228 NKYGEDFTRATINCY 3242
            N    +    T + Y
Sbjct: 314  NTVTGNTQTRTASTY 328



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 33/133 (24%), Positives = 53/133 (39%), Gaps = 12/133 (9%)

Query: 3807 KIKELERGRISDAPKEEPIVSTPPKFITQIKSHT-VEESEGVRFECRVEPKEDPKLRIEW 3865
            KI+      +S +   +  V   P F + + S   V E++ V   C    +  P   + W
Sbjct: 136  KIRTSSSSPLSPSASWDLNVKVAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPN--VTW 193

Query: 3866 YRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED-FTK-ATISCKK 3923
                   P  H        G  +L +L +    +G Y C+A+ND G    T+  TI  + 
Sbjct: 194  VNKTSGSPVAH------GTGSATLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTIIVQY 247

Query: 3924 LPDII-LQNQVPR 3935
             P+I  +QN   R
Sbjct: 248  PPEITPIQNTTVR 260



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 13/105 (12%)

Query: 1304 DITVMQAPQFSRALHN-IETVEGTNVHLECRLQPVGDQTMRVEWF--CNGKPIKTGHRFR 1360
            D+ V  AP F+ +L + ++  E  +V   C     G     V W    +G P+       
Sbjct: 152  DLNVKVAPAFTSSLSSSLDVAENDDVTNTCSAS--GRPAPNVTWVNKTSGSPV------- 202

Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAK 1405
             A+      L LL +    +G+Y CQA N +G    +  + +I +
Sbjct: 203  -AHGTGSATLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTIIVQ 246



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 12/40 (30%), Positives = 23/40 (57%)

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            G   L++  +  H AG Y C+A N +G+   + ++TI+ +
Sbjct: 207  GSATLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTIIVQ 246


>SB_59628| Best HMM Match : I-set (HMM E-Value=5e-21)
          Length = 209

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 55/200 (27%), Positives = 80/200 (40%), Gaps = 20/200 (10%)

Query: 4511 IVPPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTY 4569
            IV  +FT+T   NV+   G  + L     G     V W K G  +Q   R         +
Sbjct: 10   IVNATFTVTIGANVSALRGSSITLTCTAEGLPVPAVVWKKGGATLQQGGR--------AF 61

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKD-KPKPQTKAANAPPEIIEP 4628
            TL   E+   DSG+Y+CVA N  G A   +   +     K   PK  +   N      + 
Sbjct: 62   TLSSTES--ADSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKR 119

Query: 4629 LKDKIVA------EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            L   I+       EG+ +E  C  +G P P V W+     +  S   ++        L I
Sbjct: 120  LFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSI 177

Query: 4683 SEAFPEDEGDYKCVAYNSAG 4702
             E   E++G Y C + N+AG
Sbjct: 178  IEITAEEQGQYMCKSKNTAG 197



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 53/217 (24%), Positives = 85/217 (39%), Gaps = 32/217 (14%)

Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALD 3756
            FTV I  N+    G  +   C  E  G P   + W   G     G R  TL+        
Sbjct: 15   FTVTIGANVSALRGSSITLTCTAE--GLPVPAVVWKKGGATLQQGGRAFTLSS------- 65

Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERGRI 3816
                 + D+G Y C ATN  G+A  ++ +T                   +KI++    +I
Sbjct: 66   ---TESADSGRYDCVATNLKGTAMASSAVTIH-----------------DKIEKRVAPKI 105

Query: 3817 SDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGH 3876
              + K+  I S   +    I    +   EG   E +      PK  + W+ NG  +    
Sbjct: 106  LSS-KKNLIASENKRLFYHIIGGNITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESD 164

Query: 3877 RYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGED 3913
              +   + G  +L I+ + AE+ G+Y+C++ N  GED
Sbjct: 165  TLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGED 199



 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 59/224 (26%), Positives = 83/224 (37%), Gaps = 31/224 (13%)

Query: 1846 FITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALD 1905
            F   +        G S    C  E  P P   V W   G  LQ G R          A  
Sbjct: 15   FTVTIGANVSALRGSSITLTCTAEGLPVP--AVVWKKGGATLQQGGR----------AFT 62

Query: 1906 ILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLEDDSRYK 1965
            + +    DSG Y C A N  G A++S  + +  K            +EK    +  S  K
Sbjct: 63   LSSTESADSGRYDCVATNLKGTAMASSAVTIHDK------------IEKRVAPKILSSKK 110

Query: 1966 RAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHR 2025
              +  ++  +     G    N  + EG  + L+     +  P   V W+ NG  V +   
Sbjct: 111  NLIASENKRLFYHIIGG---NITILEGKDLELQCP--SIGTPKPAVTWFINGSAVTESDT 165

Query: 2026 FKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             K   + G  AL I+   AE+ G YMCK+ N  GE + TS   V
Sbjct: 166  LKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETSYTTV 207



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 56/211 (26%), Positives = 83/211 (39%), Gaps = 30/211 (14%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N     G  + L  T T    P   V W   G  +QQG R          A  +    + 
Sbjct: 22   NVSALRGSSITL--TCTAEGLPVPAVVWKKGGATLQQGGR----------AFTLSSTESA 69

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQP 2105
            D+G Y C ATN  G A+ +S+V +        D ++++   KI   +K      I  E  
Sbjct: 70   DSGRYDCVATNLKGTAMASSAVTIH-------DKIEKRVAPKILSSKK----NLIASEN- 117

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
              + +F   +     + EG     +C    I  P   + WF NG  +      +   + G
Sbjct: 118  --KRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLKVDPNTG 173

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNT 2196
              AL I+   AE+ G YMCK+ N  GE + T
Sbjct: 174  --ALSIIEITAEEQGQYMCKSKNTAGEDLET 202



 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 46/169 (27%), Positives = 75/169 (44%), Gaps = 20/169 (11%)

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESK 1161
            A  ++S  + DSG Y  VA N  G A  S+++T+  +  I+     + L  K   I    
Sbjct: 60   AFTLSSTESADSGRYDCVATNLKGTAMASSAVTIHDK--IEKRVAPKILSSKKNLIA--- 114

Query: 1162 FVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVT 1221
                       S++K +F   +     + EGK++ L+C    +G P   V WF NG +VT
Sbjct: 115  -----------SENKRLFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVT 161

Query: 1222 VGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVI 1270
                 K   + G  AL II  T+ + G+Y  ++ N  G    ++   V+
Sbjct: 162  ESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETSYTTVV 208



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 48/200 (24%), Positives = 74/200 (37%), Gaps = 23/200 (11%)

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
           N     G+         G P P V W K G  L    +             + +T+ +DS
Sbjct: 22  NVSALRGSSITLTCTAEGLPVPAVVWKKGGATLQQGGR----------AFTLSSTESADS 71

Query: 334 GHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQ 393
           G Y  +A N  G  + S  + +    E  V  +    I  +++      I    K L   
Sbjct: 72  GRYDCVATNLKGTAMASSAVTIHDKIEKRVAPK----ILSSKKN----LIASENKRLFYH 123

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
            +    +  + EGK     C   G P P VTWFIN   + +    K+   +    AL I 
Sbjct: 124 IIG--GNITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV---DPNTGALSII 178

Query: 454 NVTLSDSGVVTCVARNKSGE 473
            +T  + G   C ++N +GE
Sbjct: 179 EITAEEQGQYMCKSKNTAGE 198



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 45/183 (24%), Positives = 71/183 (38%), Gaps = 31/183 (16%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G      C   G P P V W      +           + G  A  +++   +DSG   C
Sbjct: 28  GSSITLTCTAEGLPVPAVVWKKGGATL-----------QQGGRAFTLSSTESADSGRYDC 76

Query: 466 VARNKSGETAFQCRLNVIEK-EQVVAPKFVERFSTL-----------------NVREGEP 507
           VA N  G       + + +K E+ VAPK +     L                  + EG+ 
Sbjct: 77  VATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYHIIGGNITILEGKD 136

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           + L   ++GTP P +TW  +G  +  +  L++  + GA  L I    A +   Y C ++N
Sbjct: 137 LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTGA--LSIIEITAEEQGQYMCKSKN 194

Query: 568 VAG 570
            AG
Sbjct: 195 TAG 197



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 55/210 (26%), Positives = 87/210 (41%), Gaps = 32/210 (15%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            N+  + G+++ L C  +  G     V W   G  ++ G R          A  L S    
Sbjct: 22   NVSALRGSSITLTCTAE--GLPVPAVVWKKGGATLQQGGR----------AFTLSSTESA 69

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDE 1438
            DSG Y C ATN  G A+ S A+ +  K +  +  +  S  + +   E+   +    II  
Sbjct: 70   DSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYH--IIGG 127

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            ++TI              +EG+ +  +C    +      V WF NG  VT     +   +
Sbjct: 128  NITI--------------LEGKDLELQCP--SIGTPKPAVTWFINGSAVTESDTLKVDPN 171

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTD 1528
             G  AL II++ AE+ G Y C++ N  G D
Sbjct: 172  TG--ALSIIEITAEEQGQYMCKSKNTAGED 199



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 53/193 (27%), Positives = 81/193 (41%), Gaps = 31/193 (16%)

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G +I  +C   G P+P V W KG   ++     Q  R    +TL  +E+   D G Y CV
Sbjct: 28   GSSITLTCTAEGLPVPAVVWKKGGATLQ-----QGGRA---FTLSSTES--ADSGRYDCV 77

Query: 4697 AYNSAGR------VTVAAKL-KVTQP---DQADNLPALTPLR--------DIVVYEGQPA 4738
            A N  G       VT+  K+ K   P       NL A    R        +I + EG+  
Sbjct: 78   ATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYHIIGGNITILEGKDL 137

Query: 4739 QFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTA 4798
            + +       KP + W   G+ + E+   ++  + N   L I     E+ G + C++   
Sbjct: 138  ELQCPSIGTPKPAVTWFINGSAVTESDTLKV--DPNTGALSIIEITAEEQGQYMCKSKNT 195

Query: 4799 AGQ-VETSAKLVV 4810
            AG+ +ETS   VV
Sbjct: 196  AGEDLETSYTTVV 208



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 52/213 (24%), Positives = 81/213 (38%), Gaps = 31/213 (14%)

Query: 2644 FTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLS 2703
            FT  + +    + G  + L    E    P   + W K G TL  G R            +
Sbjct: 15   FTVTIGANVSALRGSSITLTCTAEGLPVP--AVVWKKGGATLQQGGR----------AFT 62

Query: 2704 INSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDRIGALXXXXXXX 2763
            ++S  + DSG Y C ATNL G A++++++ I D+   + + + P  L     L       
Sbjct: 63   LSSTESADSGRYDCVATNLKGTAMASSAVTIHDK---IEKRVAPKILSSKKNLIASENKR 119

Query: 2764 XXXXXXXXXXXVFISHLNNIVCKEGDNIHFECNVEPS-RDPTLKIEWFFNNKPLPSGTRY 2822
                              NI   EG ++  +C   PS   P   + WF N   +      
Sbjct: 120  LFYHIIG----------GNITILEGKDLELQC---PSIGTPKPAVTWFINGSAVTESDTL 166

Query: 2823 KSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            K   D +  +L I     E+ G Y CK+ N+ G
Sbjct: 167  KV--DPNTGALSIIEITAEEQGQYMCKSKNTAG 197



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 23/206 (11%)

Query: 931  ARLEPIGDSTLRVEWLKDGRPVEAS--SRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
            A +  +  S++ +    +G PV A    +       G  A T+ S    D+G Y C A N
Sbjct: 21   ANVSALRGSSITLTCTAEGLPVPAVVWKKGGATLQQGGRAFTLSSTESADSGRYDCVATN 80

Query: 989  AIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYSKRTEEEVKITQKPRFLGP 1048
              G A  S+ +TI  K            +EK      A +     +  +    K  F   
Sbjct: 81   LKGTAMASSAVTIHDK------------IEK----RVAPKILSSKKNLIASENKRLFYHI 124

Query: 1049 LKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASV 1108
            + G   I+EG+    E +          V W+ NG  +T ++ ++   + G  AL I  +
Sbjct: 125  IGGNITILEGKD--LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEI 180

Query: 1109 RAEDSGVYTVVARNAAGEAQLSASMT 1134
             AE+ G Y   ++N AGE  L  S T
Sbjct: 181  TAEEQGQYMCKSKNTAGE-DLETSYT 205



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 42/157 (26%), Positives = 62/157 (39%), Gaps = 20/157 (12%)

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGEXXXXXXXXXXXXXXIQLETQHPEGMKKIQKLEQPH 2494
            + T+S     D G Y C A+NL G                   T H     KI+K   P 
Sbjct: 60   AFTLSSTESADSGRYDCVATNLKGTAMASSAV-----------TIHD----KIEKRVAPK 104

Query: 2495 ERRSEEPDREFE-KPIFTQVLTGPSELWEGQHAHYEARVVPVGDPSLRFEWYINGVELKM 2553
               S++     E K +F  ++ G   + EG+    E +   +G P     W+ING  +  
Sbjct: 105  ILSSKKNLIASENKRLFYHIIGGNITILEGKDL--ELQCPSIGTPKPAVTWFINGSAVTE 162

Query: 2554 GSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
                +   + G   L I  + A + G YMCK+ N AG
Sbjct: 163  SDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAG 197



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 35/138 (25%), Positives = 57/138 (41%), Gaps = 21/138 (15%)

Query: 3113 TKTTDSGTYSCRATNKWGQAEISVKLECVDK-SKGQKPRFTTHIQNIEG----------- 3160
            T++ DSG Y C ATN  G A  S  +   DK  K   P+  +  +N+             
Sbjct: 66   TESADSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYHII 125

Query: 3161 -----LKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQ 3215
                 + +G+    +C  +    P   + W+ NG  +  S  +K   + G   L I    
Sbjct: 126  GGNITILEGKDLELQCPSIGTPKP--AVTWFINGSAVTESDTLKVDPNTG--ALSIIEIT 181

Query: 3216 NHDSGEYVCRAYNKYGED 3233
              + G+Y+C++ N  GED
Sbjct: 182  AEEQGQYMCKSKNTAGED 199



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 41/163 (25%), Positives = 73/163 (44%), Gaps = 19/163 (11%)

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLNQLEDTS 1695
            A  + S    DSG Y C A N  G A+ S    +H K    +E +     P++     +S
Sbjct: 60   AFTLSSTESADSGRYDCVATNLKGTAMASSAVTIHDK----IEKR---VAPKIL----SS 108

Query: 1696 KYQRHSAQDEVITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
            K    +++++ +     + +   +I + E +    E +   +G PK  V W  NG  +  
Sbjct: 109  KKNLIASENKRL----FYHIIGGNITILEGK--DLELQCPSIGTPKPAVTWFINGSAVTE 162

Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
            S+ L    + G  AL++  +  E+ G Y C++ N  GE + +S
Sbjct: 163  SDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETS 203



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 38/165 (23%), Positives = 68/165 (41%), Gaps = 24/165 (14%)

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGKAGLEAVEQAEEAR 2894
            ++ T   DSG Y C ATN KG+A  S ++           T H       + +E+    +
Sbjct: 63   LSSTESADSGRYDCVATNLKGTAMASSAV-----------TIH-------DKIEKRVAPK 104

Query: 2895 LAKGRRPSVPDTEYPKPEWIIPIAAEHQLVEGQVLHLEGQVEPKNDPDLKIEWYFNGKVL 2954
            +   ++  +      K  +   I     ++EG+ L L  Q      P   + W+ NG  +
Sbjct: 105  ILSSKKNLIASEN--KRLFYHIIGGNITILEGKDLEL--QCPSIGTPKPAVTWFINGSAV 160

Query: 2955 EQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSS 2999
             +    K+  + G   L ++++   + G Y CK+ N  GE   +S
Sbjct: 161  TESDTLKVDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETS 203



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 48/212 (22%), Positives = 85/212 (40%), Gaps = 31/212 (14%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G +I L C  E  G P   V W   G ++  G R          A  +    SAD+G Y 
Sbjct: 28   GSSITLTCTAE--GLPVPAVVWKKGGATLQQGGR----------AFTLSSTESADSGRYD 75

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP 1311
              A N  G+A  S+ V + ++ +       ++   +I   +     ++  R    ++   
Sbjct: 76   CVATNLKGTAMASSAVTIHDKIE-------KRVAPKILSSKKNLIASENKRLFYHIIGG- 127

Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALD 1371
                   NI  +EG ++ L+C    +G     V WF NG  +      +   + +  AL 
Sbjct: 128  -------NITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLK--VDPNTGALS 176

Query: 1372 LLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            ++ +  E+ G Y C++ N  GE + +    V+
Sbjct: 177  IIEITAEEQGQYMCKSKNTAGEDLETSYTTVV 208



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
           N  + EG D + Q    G P+P VTWF NG  +  S+  ++    N   L +      + 
Sbjct: 128 NITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV--DPNTGALSIIEITAEEQ 185

Query: 334 GHYTLLAENPNGCIVTSGYLAV 355
           G Y   ++N  G  + + Y  V
Sbjct: 186 GQYMCKSKNTAGEDLETSYTTV 207



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 50/214 (23%), Positives = 84/214 (39%), Gaps = 32/214 (14%)

Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704
           +V+A+ G  I      E  G P   + W K G +++   R          +  + S    
Sbjct: 22  NVSALRGSSITLTCTAE--GLPVPAVVWKKGGATLQQGGR----------AFTLSSTESA 69

Query: 705 DSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEE 764
           DSG Y C A +  G A   +   VT    IE+    P+ L   + L              
Sbjct: 70  DSGRYDCVATNLKGTAMASSA--VTIHDKIEKRVA-PKILSSKKNLI------------- 113

Query: 765 QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFN 824
            +  +  F   +     + EG++   E Q   +  P   V W+ +G  +T S  +    N
Sbjct: 114 ASENKRLFYHIIGGNITILEGKD--LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPN 171

Query: 825 FGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
            G  +L+I+ + AE+ G Y  ++ N  GE + T+
Sbjct: 172 TG--ALSIIEITAEEQGQYMCKSKNTAGEDLETS 203



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 4/72 (5%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            I EG+     C  I  G P   V WF N   + +S  +    + G  +++I  +  E++G
Sbjct: 131  ILEGKDLELQCPSI--GTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEITAEEQG 186

Query: 2448 VYMCRASNLLGE 2459
             YMC++ N  GE
Sbjct: 187  QYMCKSKNTAGE 198



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 15/131 (11%)

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEK-RRQGRGGIVPPSFTLTAQ------------NV 4523
            DS  +  VA N  GTA  S+ + + +K  ++    I+     L A             N+
Sbjct: 70   DSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSSKKNLIASENKRLFYHIIGGNI 129

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGK 4583
             +  G+ + L     GT    V W  NG  V      K+  +  T  L I+E   ++ G+
Sbjct: 130  TILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV--DPNTGALSIIEITAEEQGQ 187

Query: 4584 YECVAINSAGE 4594
            Y C + N+AGE
Sbjct: 188  YMCKSKNTAGE 198



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 41/161 (25%), Positives = 63/161 (39%), Gaps = 24/161 (14%)

Query: 3626 DAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLEETLHKREEI 3685
            D+G Y C ATN  G A  S  + +  +    + P++ S                 K+  I
Sbjct: 70   DSGRYDCVATNLKGTAMASSAVTIHDKIEKRVAPKILSS----------------KKNLI 113

Query: 3686 TIEDEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH 3745
              E+++     F   I  NI + EG  +   C    +G P   + WF NG        + 
Sbjct: 114  ASENKR----LFYHIIGGNITILEGKDLELQC--PSIGTPKPAVTWFINGSAVTESDTLK 167

Query: 3746 TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
               + G  AL I  I A + G+Y C++ N  G    T+  T
Sbjct: 168  VDPNTG--ALSIIEITAEEQGQYMCKSKNTAGEDLETSYTT 206



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG+   LE Q      P   + WF NG  +T    LK   + G   LSI  +  ++ G
Sbjct: 131  ILEGKD--LELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTG--ALSIIEITAEEQG 186

Query: 2714 IYTCKATNLLGEAVSTA 2730
             Y CK+ N  GE + T+
Sbjct: 187  QYMCKSKNTAGEDLETS 203



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 4/98 (4%)

Query: 905  STQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNF 964
            S  K  F   I   I+I EG     E +   IG     V W  +G  V  S  +    N 
Sbjct: 115  SENKRLFYHIIGGNITILEG--KDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNT 172

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            G  AL+I  +T  + G Y C++ N  G+   ++  T+V
Sbjct: 173  G--ALSIIEITAEEQGQYMCKSKNTAGEDLETSYTTVV 208



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 2/70 (2%)

Query: 3988 METTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYL 4047
            +E    E Q   +G P   V WF NG  +   +  T   D    A++   +  E+ G+Y+
Sbjct: 132  LEGKDLELQCPSIGTPKPAVTWFINGSAVTESD--TLKVDPNTGALSIIEITAEEQGQYM 189

Query: 4048 CRATNLYGMD 4057
            C++ N  G D
Sbjct: 190  CKSKNTAGED 199



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 13/40 (32%), Positives = 20/40 (50%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            +T+ EG+     C   G PKP V W +NG+ +      K+
Sbjct: 129  ITILEGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKV 168



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 3436 ENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFV-ILEISPTYPEDSGEYL 3494
            E    E +      P   V W+ NG ++      +   + G + I+EI+    E+ G+Y+
Sbjct: 133  EGKDLELQCPSIGTPKPAVTWFINGSAVTESDTLKVDPNTGALSIIEITA---EEQGQYM 189

Query: 3495 CRAYNNYGEAVTTA 3508
            C++ N  GE + T+
Sbjct: 190  CKSKNTAGEDLETS 203



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 10/74 (13%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           + ++   G  + L   A G P P + W+K G          +   G A TL     +++D
Sbjct: 21  ANVSALRGSSITLTCTAEGLPVPAVVWKKGGA--------TLQQGGRAFTLS--STESAD 70

Query: 558 AAWYQCTAQNVAGS 571
           +  Y C A N+ G+
Sbjct: 71  SGRYDCVATNLKGT 84


>SB_36553| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 684

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 23/189 (12%)

Query: 389 ALAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN 447
           ++AP F   +    +V+E       C  +G P P VTW        +  +   + + +G+
Sbjct: 3   SVAPTFTSSLSSSHEVSENDDFNVTCSASGHPDPNVTWV-------NKLSGSAVAHGTGS 55

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
             L +  +    +GV  C A N     A    + +     V  P  +       VR GE 
Sbjct: 56  ATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTI----NVQYPPKITPIQNTTVRAGET 111

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           + L     G PTP ++W K G           H+ GG +      A  +D   Y CTA N
Sbjct: 112 ITLTCAVAGNPTPSVSWSKAGSG---------HSTGG-NVFTKAGATKADTGQYVCTAVN 161

Query: 568 -VAGSTATR 575
            V G+T TR
Sbjct: 162 TVTGNTQTR 170



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 66/245 (26%), Positives = 98/245 (40%), Gaps = 34/245 (13%)

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKA 389
           K+ SGH T       G + T    A ++ T  YV    +    +TQ R     + +  K 
Sbjct: 130 KAGSGHST------GGNVFTKAG-ATKADTGQYVCTAVNTVTGNTQTRTASTYVMVKYK- 181

Query: 390 LAPQFVKVCQDRDVTEGK-MTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
             P  +    D+ V E     +  C   G P P  TWF      RD     ++V+ +  +
Sbjct: 182 --PSILSKSPDQTVNETTGFLKLTCISDGYPTPTFTWF------RDG----LVVSRTSVY 229

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508
                +VT S++G  TC A N+    A   ++ V  K ++V+       ST N    +  
Sbjct: 230 --YSNSVTRSEAGTYTCTATNEMMSDATTVQVTVNYKPEMVS-------STTNTSSWDRK 280

Query: 509 VLN--ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
           VL+   +A G P P+ITW   G   I      I   GG+         A D   Y+C A 
Sbjct: 281 VLSLQCKARGVPLPQITWYNPGGQPITAGVSPI--SGGSQNQVATTRDAGDYGPYKCRAF 338

Query: 567 NVAGS 571
           N+ GS
Sbjct: 339 NLLGS 343



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 10/100 (10%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            ++ AP F + L+   ++SE    +  C    +PDPN  V W    K+  S   + T    
Sbjct: 2    ISVAPTFTSSLSSSHEVSENDDFNVTCSASGHPDPN--VTWV--NKLSGSAVAHGT---- 53

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNL--GQAVSSIRLNVQ 1937
            G A L +L +    +G Y C+A N++  G     + +NVQ
Sbjct: 54   GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTINVQ 93



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 45/186 (24%), Positives = 71/186 (38%), Gaps = 28/186 (15%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V+E      +C   G P P V W   +KL   +    ++      TL + +      G Y
Sbjct: 18   VSENDDFNVTCSASGHPDPNVTWV--NKLSGSA----VAHGTGSATLSLLKIQRHQAGVY 71

Query: 4694 KCVAYNSA--GRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            +C A N    G +T    + V  P      P +TP+++  V  G+       +     P+
Sbjct: 72   QCQATNDVRRGAITQDVTINVQYP------PKITPIQNTTVRAGETITLTCAVAGNPTPS 125

Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRA-TTAAGQVET---SAK 4807
            + W + G+             G N     G T + DTG + C A  T  G  +T   S  
Sbjct: 126  VSWSKAGS---------GHSTGGNVFTKAGAT-KADTGQYVCTAVNTVTGNTQTRTASTY 175

Query: 4808 LVVKSK 4813
            ++VK K
Sbjct: 176  VMVKYK 181



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 67/293 (22%), Positives = 108/293 (36%), Gaps = 44/293 (15%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP  T   QN  V +G+ + L   V G     V W K G               G     
Sbjct: 95   PPKIT-PIQNTTVRAGETITLTCAVAGNPTPSVSWSKAGSG----------HSTGGNVFT 143

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
               A   D+G+Y C A+N+                T+ +           P I+    D+
Sbjct: 144  KAGATKADTGQYVCTAVNTV------------TGNTQTRTASTYVMVKYKPSILSKSPDQ 191

Query: 4633 IVAEGQA-IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
             V E    ++ +C   G P PT  W++ D L+       +SRT+  Y+  ++ +   + G
Sbjct: 192  TVNETTGFLKLTCISDGYPTPTFTWFR-DGLV-------VSRTSVYYSNSVTRS---EAG 240

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
             Y C A N    ++ A  ++VT   + + + + T   +   ++ +    + +      P 
Sbjct: 241  TYTCTATNE--MMSDATTVQVTVNYKPEMVSSTT---NTSSWDRKVLSLQCKARGVPLPQ 295

Query: 4752 IQWLREGALIPETPDFQMIHEGN-NAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
            I W   G   P T     I  G+ N V    +    D G + CRA    G VE
Sbjct: 296  ITWYNPGGQ-PITAGVSPISGGSQNQVATTRDA--GDYGPYKCRAFNLLGSVE 345



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 47/177 (26%), Positives = 75/177 (42%), Gaps = 21/177 (11%)

Query: 1788 INEL-GEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRF 1846
            +N+L G AV   T    +  SL    +H++ + + Q   D  R    +DV + V   P+ 
Sbjct: 41   VNKLSGSAVAHGT--GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTINVQYPPK- 97

Query: 1847 ITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDI 1906
            IT +   T +  G++    C +   P P+  V W   G    SGH     N F  A    
Sbjct: 98   ITPIQNTT-VRAGETITLTCAVAGNPTPS--VSWSKAG----SGHS-TGGNVFTKAGAT- 148

Query: 1907 LTVYGEDSGEYTCKAIN----NLGQAVSSIRLNVQSKESIIRDSQHESALEKIQYLE 1959
                  D+G+Y C A+N    N     +S  + V+ K SI+  S  ++  E   +L+
Sbjct: 149  ----KADTGQYVCTAVNTVTGNTQTRTASTYVMVKYKPSILSKSPDQTVNETTGFLK 201



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 8/97 (8%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            +  AP FT+ L S  ++ E     +        DPN  + W      L+  A    T   
Sbjct: 2    ISVAPTFTSSLSSSHEVSENDDFNVTCSASGHPDPN--VTWVNK---LSGSAVAHGT--- 53

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  TLS+  ++   +G+Y C+ATN +     T  + I
Sbjct: 54   GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTI 90



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 14/118 (11%)

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
            +++GTY+C ATN     E+      V  +   KP   +   N     D +    +C    
Sbjct: 237  SEAGTYTCTATN-----EMMSDATTVQVTVNYKPEMVSSTTNTSSW-DRKVLSLQCKARG 290

Query: 3176 VDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231
            V  P  +I WY+  GQP+  +  +  +S  G     +A T++  D G Y CRA+N  G
Sbjct: 291  VPLP--QITWYNPGGQPI--TAGVSPIS--GGSQNQVATTRDAGDYGPYKCRAFNLLG 342



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 17/139 (12%)

Query: 3104 GMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD 3163
            G   L +L  +   +G Y C+ATN   +  I+  +        Q P   T IQN   ++ 
Sbjct: 54   GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTI----NVQYPPKITPIQNTT-VRA 108

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G++    C V    +P   + W   G    HST        G  V   A     D+G+YV
Sbjct: 109  GETITLTCAV--AGNPTPSVSWSKAGS--GHST--------GGNVFTKAGATKADTGQYV 156

Query: 3224 CRAYNKYGEDFTRATINCY 3242
            C A N    +    T + Y
Sbjct: 157  CTAVNTVTGNTQTRTASTY 175



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 39/134 (29%), Positives = 55/134 (41%), Gaps = 15/134 (11%)

Query: 1941 SIIRDSQHESALEKIQYLEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEAT 2000
            S+++  +H++ + + Q   +D R     QD +  V+ P    PI+N  V  G  + L  T
Sbjct: 59   SLLKIQRHQAGVYQCQ-ATNDVRRGAITQDVTINVQYPPKITPIQNTTVRAGETITL--T 115

Query: 2001 LTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAV-G 2059
                 +PT  V W   G     GH        G        A   DTG Y+C A N V G
Sbjct: 116  CAVAGNPTPSVSWSKAG----SGH------STGGNVFTKAGATKADTGQYVCTAVNTVTG 165

Query: 2060 EAVT-TSSVKVDAK 2072
               T T+S  V  K
Sbjct: 166  NTQTRTASTYVMVK 179



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 12/115 (10%)

Query: 3825 IVSTPPKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            ++S  P F + + S H V E++     C      DP   + W    KL  S   + T   
Sbjct: 1    MISVAPTFTSSLSSSHEVSENDDFNVTCSASGHPDPN--VTWVN--KLSGSAVAHGT--- 53

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDF--GEDFTKATISCKKLPDII-LQNQVPR 3935
             G  +L +L +    +G Y C+A ND   G      TI+ +  P I  +QN   R
Sbjct: 54   -GSATLSLLKIQRHQAGVYQCQATNDVRRGAITQDVTINVQYPPKITPIQNTTVR 107



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 8/80 (10%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F ++L+S   + E D  +  C      DP++T  W +   K+         H  G   
Sbjct: 6    PTFTSSLSSSHEVSENDDFNVTCSASGHPDPNVT--WVN---KLSGS---AVAHGTGSAT 57

Query: 2169 LDILYTYAEDSGTYMCKATN 2188
            L +L      +G Y C+ATN
Sbjct: 58   LSLLKIQRHQAGVYQCQATN 77



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 14/31 (45%), Positives = 21/31 (67%)

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            +AG YTC ATN+  S  TT ++T + K ++V
Sbjct: 238  EAGTYTCTATNEMMSDATTVQVTVNYKPEMV 268



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 3/48 (6%)

Query: 4111 PVFVS-LPDAVTVEEGEWARFCCRVTGHPKPRVMWL--LNGNTIVNGS 4155
            P F S L  +  V E +     C  +GHP P V W+  L+G+ + +G+
Sbjct: 6    PTFTSSLSSSHEVSENDDFNVTCSASGHPDPNVTWVNKLSGSAVAHGT 53



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 35/125 (28%), Positives = 52/125 (41%), Gaps = 17/125 (13%)

Query: 1172 ISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD 1231
            I+   P  + P+ N   V  G+ I L C +   G+PT  V W   G   + G    T   
Sbjct: 90   INVQYPPKITPIQNTT-VRAGETITLTCAVA--GNPTPSVSWSKAGSGHSTGGNVFTKAG 146

Query: 1232 FGFVALDIIHATSADTGEYTVRAVNHL-GSAHT---SAIVRVIERSDIVTDTQNEQAIEQ 1287
                      AT ADTG+Y   AVN + G+  T   S  V V  +  I++ + ++   E 
Sbjct: 147  ----------ATKADTGQYVCTAVNTVTGNTQTRTASTYVMVKYKPSILSKSPDQTVNET 196

Query: 1288 IQLLE 1292
               L+
Sbjct: 197  TGFLK 201



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 13/112 (11%)

Query: 908  KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
            KP   +   DQ   +  GF       +  G  T    W +DG  V   SR + +++    
Sbjct: 181  KPSILSKSPDQTVNETTGFLKLTCISD--GYPTPTFTWFRDGLVV---SRTSVYYS---- 231

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEK 1019
                 SVT  +AG YTC A N +    T+  +T+  K ++++ + +    ++
Sbjct: 232  ----NSVTRSEAGTYTCTATNEMMSDATTVQVTVNYKPEMVSSTTNTSSWDR 279


>SB_37863| Best HMM Match : I-set (HMM E-Value=3.1e-14)
          Length = 188

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 35/145 (24%), Positives = 73/145 (50%), Gaps = 5/145 (3%)

Query: 383 IEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILV 442
           ++I +    P+ ++  +D +  E    +FD ++   P  EV W+    +I D   + +  
Sbjct: 39  LDIVKSKSKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQ 98

Query: 443 NES-GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL- 500
           +E  G +++ I ++ L D G    VA N  G+T+ +  L V  KE+++AP+F  R + + 
Sbjct: 99  DEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV--KEKLIAPEFEGRETEVP 156

Query: 501 -NVREGEPVVLNARAVGTPTPRITW 524
              +E   + ++    G P+P +++
Sbjct: 157 FRAKEKSDLEVSYNINGKPSPDVSY 181



 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 2/98 (2%)

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADE- 4677
            + + PEI+E +KD    E    +F  KI   P   V+WY     I     + +++  ++ 
Sbjct: 44   SKSKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDG 103

Query: 4678 -YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
             Y++ I++   ED G YK VA+N  G+ +  A+L V +
Sbjct: 104  TYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKE 141



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 34/114 (29%), Positives = 50/114 (43%), Gaps = 5/114 (4%)

Query: 1027 SRYSKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQI 1086
            S YS    + VK   KP  L  +K    I  G+ A F+ +++        VEWY    +I
Sbjct: 32   STYSSANLDIVKSKSKPEILETMKDAEGIETGK-AKFDVKIKAYPKAE--VEWYHRSARI 88

Query: 1087 TSANRIQTYHDF--GYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVETR 1138
                R     D   G  ++ I  +R ED G Y +VA N  G+    A +TV+ +
Sbjct: 89   YDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 24/85 (28%), Positives = 40/85 (47%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           S P   +  K+A   + G AKF+ K++  P   V W  + A + +  +Y +  +E+ G  
Sbjct: 46  SKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTY 105

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGE 154
           S+ I  +   D G Y   A N  G+
Sbjct: 106 SVTINDLRLEDCGTYKIVAFNDIGK 130



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 49/195 (25%), Positives = 79/195 (40%), Gaps = 22/195 (11%)

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVN 4524
            K  L  ++V + D   +    +N  G+   SANL + + + +       P    T ++  
Sbjct: 6    KCTLNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKSK-------PEILETMKDAE 58

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKIL--EEDGTYTLLILEAYPQDSG 4582
                   + D K+      +V W     ++    R  +   EEDGTY++ I +   +D G
Sbjct: 59   GIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCG 118

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDK-PKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
             Y+ VA N  G+    AE  V     K+K   P+ +      E   P + K   E   +E
Sbjct: 119  TYKIVAFNDIGKTSERAELTV-----KEKLIAPEFEGR----ETEVPFRAK---EKSDLE 166

Query: 4642 FSCKIVGKPLPTVQW 4656
             S  I GKP P V +
Sbjct: 167  VSYNINGKPSPDVSY 181



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 4102 VEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            + +SK++ P +  ++ DA  +E G+ A+F  ++  +PK  V W      I +G RY LT 
Sbjct: 41   IVKSKSK-PEILETMKDAEGIETGK-AKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQ 98

Query: 4162 ---DGMYHFDIPKTRQYDTGKIEVI 4183
               DG Y   I   R  D G  +++
Sbjct: 99   DEEDGTYSVTINDLRLEDCGTYKIV 123



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 765 QTSQRPQFIRPLQDLGELQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSR--ITSI 822
           ++  +P+ +  ++D   ++ G+ A F+ ++     P   VEWY     I    R  +T  
Sbjct: 43  KSKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQD 99

Query: 823 FNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTASIRV 862
              G  S+ I  LR ED G+Y + A N +G+    A + V
Sbjct: 100 EEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV 139



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 26/90 (28%), Positives = 48/90 (53%), Gaps = 5/90 (5%)

Query: 2372 TRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSR--ITKTH 2429
            ++ +P   + +++ + I+ G+ A FD ++     P  +VEW+     I D  R  +T+  
Sbjct: 44   SKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDE 100

Query: 2430 DFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            + G  S+TI+ +R ED G Y   A N +G+
Sbjct: 101  EDGTYSVTINDLRLEDCGTYKIVAFNDIGK 130



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 5/96 (5%)

Query: 2108 RPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD--FG 2165
            +P  L  +   E ++ G +A F+ +++    P   ++W+H   +I  G RY  T D   G
Sbjct: 47   KPEILETMKDAEGIETG-KAKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDEEDG 103

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
              ++ I     ED GTY   A N +G+      L V
Sbjct: 104  TYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTV 139



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 6/111 (5%)

Query: 2229 STRIEVEEPKISPPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSA 2288
            S  +++ + K S P  +  ++    +  GK A F+ +++    P   +E+YH    +   
Sbjct: 36   SANLDIVKSK-SKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDG 91

Query: 2289 ARFHITFDF--GYVSLDIQHCVPEDAGEYSVKAINALGHCTSAISMTVTAK 2337
             R+ +T D   G  S+ I     ED G Y + A N +G  +    +TV  K
Sbjct: 92   GRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 5/89 (5%)

Query: 3840 TVEESEGV---RFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM--GFVSLDILYV 3894
            T++++EG+   + +  V+ K  PK  +EWY     +  G RY    D   G  S+ I  +
Sbjct: 53   TMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDL 112

Query: 3895 YAEDSGEYICRAVNDFGEDFTKATISCKK 3923
              ED G Y   A ND G+   +A ++ K+
Sbjct: 113  RLEDCGTYKIVAFNDIGKTSERAELTVKE 141



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 5/105 (4%)

Query: 902  VPESTQKPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSR--IT 959
            + +S  KPE    +KD   I E G A F+ +++    +   VEW      +    R  +T
Sbjct: 41   IVKSKSKPEILETMKDAEGI-ETGKAKFDVKIKAYPKA--EVEWYHRSARIYDGGRYCLT 97

Query: 960  TFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
                 G  ++TI  + + D G Y   A+N IG+ +  A LT+  K
Sbjct: 98   QDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNR--LTTMHDFGYV 1768
            P     MKD    E   A F+ ++     PK  VEW      I    R  LT   + G  
Sbjct: 48   PEILETMKDAEGIETGKAKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDEEDGTY 105

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSK 1805
            ++ +  +  ED GTY   A N++G+    + L V+ K
Sbjct: 106  SVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 1578 PICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRF--TETNNFGFV 1635
            P    ++K+ E  E  +A F+ ++     A  +VEWYH +  +  G R+  T+    G  
Sbjct: 48   PEILETMKDAEGIETGKAKFDVKIKAYPKA--EVEWYHRSARIYDGGRYCLTQDEEDGTY 105

Query: 1636 ALDIMSCLPEDSGTYTCRAINALGE 1660
            ++ I     ED GTY   A N +G+
Sbjct: 106  SVTINDLRLEDCGTYKIVAFNDIGK 130



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%)

Query: 2666 VEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF--GLVTLSINSLRNDDSGIYTCKATNLL 2723
            V+ +  P  ++EW+     +  G R   T D   G  +++IN LR +D G Y   A N +
Sbjct: 69   VKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDI 128

Query: 2724 GEAVSTASIKIEDR 2737
            G+    A + ++++
Sbjct: 129  GKTSERAELTVKEK 142



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 4/88 (4%)

Query: 2935 VEPKNDPDLKIEWYFNGKVLEQGSRFKLTSD--FGFVTLDLVDVYERDSGIYTCKAYNKR 2992
            V+ K  P  ++EWY     +  G R+ LT D   G  ++ + D+   D G Y   A+N  
Sbjct: 69   VKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDI 128

Query: 2993 GEAFTSSTVYCTSKDNLIERTQHPKGTE 3020
            G+  TS     T K+ LI      + TE
Sbjct: 129  GK--TSERAELTVKEKLIAPEFEGRETE 154



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 4/113 (3%)

Query: 1962 SRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQ 2021
            S Y  A  D      KP+  + +K+AE  E      +  +     P   VEWY     + 
Sbjct: 32   STYSSANLDIVKSKSKPEILETMKDAEGIETGKAKFDVKIKAY--PKAEVEWYHRSARIY 89

Query: 2022 QGHRFKTTYDF--GYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
             G R+  T D   G  ++ I     ED GTY   A N +G+    + + V  K
Sbjct: 90   DGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 1173 SKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYD- 1231
            SKSKP  ++ + +   +  GK    + +++    P   VEW+H    +  G R+    D 
Sbjct: 44   SKSKPEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCLTQDE 100

Query: 1232 -FGFVALDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIER 1272
              G  ++ I      D G Y + A N +G     A + V E+
Sbjct: 101  EDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 29/131 (22%), Positives = 46/131 (35%), Gaps = 4/131 (3%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L    V LSD G  T   +N  G T     L++++ +    P+ +E        E     
Sbjct: 9   LNFKRVQLSDQGSYTVTFKNAHGSTYSSANLDIVKSKS--KPEILETMKDAEGIETGKAK 66

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTD--GGASTLDIPRAKASDAAWYQCTAQN 567
            + +    P   + W      I       +  D   G  ++ I   +  D   Y+  A N
Sbjct: 67  FDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTYSVTINDLRLEDCGTYKIVAFN 126

Query: 568 VAGSTATRARL 578
             G T+ RA L
Sbjct: 127 DIGKTSERAEL 137



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 18/84 (21%), Positives = 40/84 (47%), Gaps = 2/84 (2%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT- 322
           S P+I +  ++++  E   A+F V++   P+  V W+    R+ +  ++ +       T 
Sbjct: 46  SKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEEDGTY 105

Query: 323 -LRVRNTQKSDSGHYTLLAENPNG 345
            + + + +  D G Y ++A N  G
Sbjct: 106 SVTINDLRLEDCGTYKIVAFNDIG 129



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 4/102 (3%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDF---QIHT 4461
            VK    P   + M+     E  +A+F+V+    P   ++WY  +  I +   +   Q   
Sbjct: 42   VKSKSKPEILETMKDAEGIETGKAKFDVKIKAYPKAEVEWYHRSARIYDGGRYCLTQDEE 101

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
              T S+  I  + +ED   +  VA N  G     A L V+EK
Sbjct: 102  DGTYSV-TINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 3412 VEEEKGKAPVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRT 3471
            + + K K P     + + E +  G+ A F+ ++     P  +VEWY     +  G R+  
Sbjct: 41   IVKSKSK-PEILETMKDAEGIETGK-AKFDVKIKAY--PKAEVEWYHRSARIYDGGRYCL 96

Query: 3472 FCDF--GFVILEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQGK 3515
              D   G   + I+    ED G Y   A+N+ G+    A + V+ K
Sbjct: 97   TQDEEDGTYSVTINDLRLEDCGTYKIVAFNDIGKTSERAELTVKEK 142


>SB_51604| Best HMM Match : I-set (HMM E-Value=2.3e-21)
          Length = 152

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 5/127 (3%)

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKD--KPKPQTKAANAPPEIIEPLKDKI-VAE 4636
            + G Y CVA N  G+ R  +   V  P       P P T   +  P +   + D + V E
Sbjct: 17   EGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLE 76

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
               I   C   G P P V W +    I     +++  TAD  T+ I  A   D G + C 
Sbjct: 77   DSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRV--TADGVTMLIDGAVVSDTGSFTCE 134

Query: 4697 AYNSAGR 4703
            A N AG+
Sbjct: 135  AENFAGK 141



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 26/55 (47%), Positives = 31/55 (56%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM 4164
            P V + + D VTV E    R  C  TG P PRV W  NGN I  G RY++T DG+
Sbjct: 62   PRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTADGV 116



 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 45/144 (31%), Positives = 66/144 (45%), Gaps = 20/144 (13%)

Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIE--KEQVVAPK------ 492
           L++ SG+  L I   T  + GV TCVA N  G+      L+VIE  K +++AP       
Sbjct: 3   LIDNSGS--LTIRGAT--EGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPL 58

Query: 493 ------FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGAS 546
                  +     + V E   + +   A G P PR+TW+++G  I      R+  DG   
Sbjct: 59  SGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTADG--V 116

Query: 547 TLDIPRAKASDAAWYQCTAQNVAG 570
           T+ I  A  SD   + C A+N AG
Sbjct: 117 TMLIDGAVVSDTGSFTCEAENFAG 140



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 4/91 (4%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            PR T+ I DN+ V E   +   C     G P  R+ W  NG   + G R     D   + 
Sbjct: 62   PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYRVTAD--GVT 117

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKI 3785
            + ID     D G +TC A N  G    T+ +
Sbjct: 118  MLIDGAVVSDTGSFTCEAENFAGKDKATSAV 148



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAE 2045
            N  V E   + +    T +  P  RV W  NG  + QG R++ T D   + +D   A   
Sbjct: 71   NVTVLEDSTIRIVCNATGL--PAPRVTWRQNGNAISQGGRYRVTADGVTMLID--GAVVS 126

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKV 2069
            DTG++ C+A N  G+   TS+V V
Sbjct: 127  DTGSFTCEAENFAGKDKATSAVIV 150



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 3816 ISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSG 3875
            ++ +P   P+  TP   I    + TV E   +R  C       P  R+ W +NG  +  G
Sbjct: 49   LAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQG 106

Query: 3876 HRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCK 3922
             RYR   D   + +D   V   D+G + C A N  G+D   + +  K
Sbjct: 107  GRYRVTADGVTMLIDGAVV--SDTGSFTCEAENFAGKDKATSAVIVK 151



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 16/135 (11%)

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNL---PALTPLR-----------DIVVYEGQ 4736
            G Y CVA N  G+    + L V +P +   L   P   PL            ++ V E  
Sbjct: 19   GVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDS 78

Query: 4737 PAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
              +     T    P + W + G  I +   +++  +G    +LI      DTG+FTC A 
Sbjct: 79   TIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAE 136

Query: 4797 TAAGQVETSAKLVVK 4811
              AG+ + ++ ++VK
Sbjct: 137  NFAGKDKATSAVIVK 151



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 11/136 (8%)

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVP--------PSFTLT-AQNVNVTS 4527
            +  V+  VA N  G  + ++ L V E R+       P        P  T+  + NV V  
Sbjct: 17   EGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVLE 76

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
               +R+    TG     V W +NG  +    R ++   DG  T+LI  A   D+G + C 
Sbjct: 77   DSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTA-DGV-TMLIDGAVVSDTGSFTCE 134

Query: 4588 AINSAGEARCDAECVV 4603
            A N AG+ +  +  +V
Sbjct: 135  AENFAGKDKATSAVIV 150



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 4/83 (4%)

Query: 392 PQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           P+   V  D   V E    R  C  TG P P VTW  N   I     +++  +      +
Sbjct: 62  PRVTIVISDNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTAD---GVTM 118

Query: 451 MITNVTLSDSGVVTCVARNKSGE 473
           +I    +SD+G  TC A N +G+
Sbjct: 119 LIDGAVVSDTGSFTCEAENFAGK 141



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 1183 LSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHA 1242
            +S+   V E   I + C     G P  RV W  NG +++ G R++   D   V + I  A
Sbjct: 68   ISDNVTVLEDSTIRIVCNAT--GLPAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGA 123

Query: 1243 TSADTGEYTVRAVNHLG-SAHTSAIV 1267
              +DTG +T  A N  G    TSA++
Sbjct: 124  VVSDTGSFTCEAENFAGKDKATSAVI 149



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 2/55 (3%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P+ R  W  NG  +  G R+R T D   VT+ I+  V +D G + C+A N AG
Sbjct: 88   GLPAPRVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAG 140



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 24/153 (15%)

Query: 1379 DSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDE 1438
            + GVYTC A N  G+   +  L VI  +   + +  P  +     L  T R   T +I +
Sbjct: 17   EGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIP----LSGTPRV--TIVISD 70

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +VT              V+E   +   C    +     +V W +NG  ++ G R+R   D
Sbjct: 71   NVT--------------VLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTAD 114

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVS 1531
               + +D    +  D+G +TC A N  G D+ +
Sbjct: 115  GVTMLID--GAVVSDTGSFTCEAENFAGKDKAT 145



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            + ++  PR    ++    + E  +    C     P P  RV W  NG  +  G RYR + 
Sbjct: 56   IPLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTA 113

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
            D     +D   V   D+G +TC+A N  G+
Sbjct: 114  DGVTMLIDGAVV--SDTGSFTCEAENFAGK 141



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 2/61 (3%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSST 3000
            P  ++ W  NG  + QG R+++T+D   VT+ +      D+G +TC+A N  G+   +S 
Sbjct: 90   PAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGAVVSDTGSFTCEAENFAGKDKATSA 147

Query: 3001 V 3001
            V
Sbjct: 148  V 148



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 19/64 (29%), Positives = 37/64 (57%), Gaps = 2/64 (3%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P  ++ W +NG  ++ G R + T D   VT+ I+     D+G +TC+A N  G+  +T++
Sbjct: 90   PAPRVTWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGKDKATSA 147

Query: 2732 IKIE 2735
            + ++
Sbjct: 148  VIVK 151



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
           N  + E +  +     +G P PRVTW +NG  +    ++ +  T +  T+ +     SD+
Sbjct: 71  NVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRV--TADGVTMLIDGAVVSDT 128

Query: 334 GHYTLLAEN 342
           G +T  AEN
Sbjct: 129 GSFTCEAEN 137



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 30/131 (22%), Positives = 53/131 (40%), Gaps = 17/131 (12%)

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQ-------------KPRFTTHIQNIEGLK 3162
            T+ G Y+C A N  GQ   +  L+ ++  K +              PR T  I +   + 
Sbjct: 16   TEGGVYTCVAANDQGQDRATSILDVIEPRKPKILAPSPLTIPLSGTPRVTIVISDNVTVL 75

Query: 3163 DGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEY 3222
            +  +    C    +  P  ++ W  NG  +    R +  +D   +++D A     D+G +
Sbjct: 76   EDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTADGVTMLIDGAVVS--DTGSF 131

Query: 3223 VCRAYNKYGED 3233
             C A N  G+D
Sbjct: 132  TCEAENFAGKD 142



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 3554 SGNPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFG 3613
            SG P        ++ + E+S+    C    +   + RV W  NG  +  G R +   D G
Sbjct: 59   SGTPRVTIVISDNVTVLEDSTIRIVCNATGL--PAPRVTWRQNGNAISQGGRYRVTAD-G 115

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
              +L I G    D G +TC+A N  G+   +  + VK
Sbjct: 116  VTML-IDGAVVSDTGSFTCEAENFAGKDKATSAVIVK 151



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            N+  +E + + + C     G    RV W  NG  I  G R+R     D V + +      
Sbjct: 71   NVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYR--VTADGVTMLIDGAVVS 126

Query: 1379 DSGVYTCQATNQLGEAVTSCALRV 1402
            D+G +TC+A N  G+   + A+ V
Sbjct: 127  DTGSFTCEAENFAGKDKATSAVIV 150



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 4/94 (4%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P  T+ +S  +N+   E++        T  P  +V W  NG ++  G R+R   D G  +
Sbjct: 62   PRVTIVIS--DNVTVLEDSTIRIVCNATGLPAPRVTWRQNGNAISQGGRYRVTAD-GVTM 118

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQ 3513
            L I      D+G + C A N  G+   T+++ V+
Sbjct: 119  L-IDGAVVSDTGSFTCEAENFAGKDKATSAVIVK 151



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 5/92 (5%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA 4032
            PR    I    +++E  T +  C     G P  +V W  NG  +    R+    D   V 
Sbjct: 62   PRVTIVISDNVTVLEDSTIRIVCNAT--GLPAPRVTWRQNGNAISQGGRYRVTADG--VT 117

Query: 4033 MNFGWVYPEDSGEYLCRATNLYGMDE-TKAVI 4063
            M        D+G + C A N  G D+ T AVI
Sbjct: 118  MLIDGAVVSDTGSFTCEAENFAGKDKATSAVI 149



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 4/75 (5%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            +N+   E   I   CN      P  ++ W  N   +  G RY+ T D   V++ I     
Sbjct: 70   DNVTVLEDSTIRIVCNATGL--PAPRVTWRQNGNAISQGGRYRVTAD--GVTMLIDGAVV 125

Query: 2841 EDSGIYTCKATNSKG 2855
             D+G +TC+A N  G
Sbjct: 126  SDTGSFTCEAENFAG 140



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 22/149 (14%)

Query: 2044 AEDTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEE 2103
            A + G Y C A N  G+   TS           LD ++ ++ K +        P P+   
Sbjct: 15   ATEGGVYTCVAANDQGQDRATS----------ILDVIEPRKPKILA-------PSPLTIP 57

Query: 2104 QPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHD 2163
              G   V +    ++  L E       C    +  P +T  W  NG  I  G RYR T D
Sbjct: 58   LSGTPRVTIVISDNVTVL-EDSTIRIVCNATGLPAPRVT--WRQNGNAISQGGRYRVTAD 114

Query: 2164 FGYVALDILYTYAEDSGTYMCKATNKLGE 2192
               + +D       D+G++ C+A N  G+
Sbjct: 115  GVTMLID--GAVVSDTGSFTCEAENFAGK 141



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 4/90 (4%)

Query: 3277 PSAEPPKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYRTFHD 3336
            P +  P+    I D   ++E  +         +  P  +V W  NG  +  G RYR   D
Sbjct: 57   PLSGTPRVTIVISDNVTVLEDSTIRIVCNATGLPAP--RVTWRQNGNAISQGGRYRVTAD 114

Query: 3337 FGIVILDILYCYEENSGEYECVATNKLGRD 3366
             G+ +L I      ++G + C A N  G+D
Sbjct: 115  -GVTML-IDGAVVSDTGSFTCEAENFAGKD 142



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P  T V  D V + E        +   TG  +  + W  NG  I    R R V A G+ +
Sbjct: 62   PRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRVTWRQNGNAISQGGRYR-VTADGVTM 118

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQ 3131
            L I G   +D+G+++C A N  G+
Sbjct: 119  L-IDGAVVSDTGSFTCEAENFAGK 141



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 10/109 (9%)

Query: 2356 LESAEPFKRPEIPEPVTRQRPVFTQPLQNI---DNIQ--EGQTAHFDCRLIPVGDPTLKV 2410
            L+  EP ++P+I  P     P+   P   I   DN+   E  T    C     G P  +V
Sbjct: 38   LDVIEP-RKPKILAPSPLTIPLSGTPRVTIVISDNVTVLEDSTIRIVCNA--TGLPAPRV 94

Query: 2411 EWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
             W +N   I    R   T D   V+M I      D G + C A N  G+
Sbjct: 95   TWRQNGNAISQGGRYRVTADG--VTMLIDGAVVSDTGSFTCEAENFAGK 141



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P  RV W +NG  I    R     D   + ++   V+  D+G++TC A N  G+   +
Sbjct: 88   GLPAPRVTWRQNGNAISQGGRYRVTADGVTMLIDGAVVS--DTGSFTCEAENFAGKDKAT 145

Query: 1798 STLFVQ 1803
            S + V+
Sbjct: 146  SAVIVK 151


>SB_39029| Best HMM Match : ig (HMM E-Value=6e-10)
          Length = 439

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 47/178 (26%), Positives = 70/178 (39%), Gaps = 12/178 (6%)

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            GQ+    C + G P P++ W K D L+   + +++        L+ S     D G+Y C+
Sbjct: 20   GQSRRLLCCMGGSPRPSITWLKDDSLLDIKENYKLEVFEQGQILQNSNVLKSDAGNYTCI 79

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD---IVVYEGQPAQFKTQITSKIKPTIQ 4753
              N  G  + +    V Q  Q D  P +    D     ++         QITS  KP + 
Sbjct: 80   GSNPLGNASHSFYFTV-QERQWDFNPIIQMHADQWNATIFSN--ITLTCQITSSKKPFVS 136

Query: 4754 WLR-EGALIPETPDFQMIHEGN-----NAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
            W+  +    P  P  + I   N        L I N   ED G + CR+T A G    S
Sbjct: 137  WIHIKNFTTPSFPRVRHILTNNGGDKWTTSLPIVNVSYEDGGKYICRSTNAIGHKNVS 194



 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 42/171 (24%), Positives = 66/171 (38%), Gaps = 7/171 (4%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G+  R  C + G P P +TW  +D  +    N+K+ V E G   L  +NV  SD+G  TC
Sbjct: 20  GQSRRLLCCMGGSPRPSITWLKDDSLLDIKENYKLEVFEQG-QILQNSNVLKSDAGNYTC 78

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW- 524
           +  N  G  +      V E++    P         N      + L  +   +  P ++W 
Sbjct: 79  IGSNPLGNASHSFYFTVQERQWDFNPIIQMHADQWNATIFSNITLTCQITSSKKPFVSWI 138

Query: 525 --QKDGVPIIPNPELRIHTDGG---ASTLDIPRAKASDAAWYQCTAQNVAG 570
             +    P  P     +  +GG    ++L I      D   Y C + N  G
Sbjct: 139 HIKNFTTPSFPRVRHILTNNGGDKWTTSLPIVNVSYEDGGKYICRSTNAIG 189



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 40/164 (24%), Positives = 68/164 (41%), Gaps = 11/164 (6%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P I W +++  +    ++++  F    IL    V   D+  +  +  N  G A  S
Sbjct: 31   GSPRPSITWLKDDSLLDIKENYKLEVFEQGQILQNSNVLKSDAGNYTCIGSNPLGNASHS 90

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYW--LKNGKK 4553
                V+E++         P   + A   N T    + L  ++T +K   V W  +KN   
Sbjct: 91   FYFTVQERQWD-----FNPIIQMHADQWNATIFSNITLTCQITSSKKPFVSWIHIKNFTT 145

Query: 4554 VQ-PDIRNKILEEDG---TYTLLILEAYPQDSGKYECVAINSAG 4593
               P +R+ +    G   T +L I+    +D GKY C + N+ G
Sbjct: 146  PSFPRVRHILTNNGGDKWTTSLPIVNVSYEDGGKYICRSTNAIG 189



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 22/68 (32%), Positives = 34/68 (50%)

Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348
           + G+PRP +TW K+   L     +++        L+  N  KSD+G+YT +  NP G   
Sbjct: 29  MGGSPRPSITWLKDDSLLDIKENYKLEVFEQGQILQNSNVLKSDAGNYTCIGSNPLGNAS 88

Query: 349 TSGYLAVE 356
            S Y  V+
Sbjct: 89  HSFYFTVQ 96



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 2672 PNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P   I W K+   L      K   F+ G +  + N L++D +G YTC  +N LG A  + 
Sbjct: 33   PRPSITWLKDDSLLDIKENYKLEVFEQGQILQNSNVLKSD-AGNYTCIGSNPLGNASHSF 91

Query: 2731 SIKIEDRHW 2739
               +++R W
Sbjct: 92   YFTVQERQW 100



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 5/101 (4%)

Query: 1842 QAPRFITQLNGPTKLSE--GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            QAP F+T LN    +    GQS    C +   P P+  + W  +  +L     Y+     
Sbjct: 2    QAP-FVTILNSTELILALTGQSRRLLCCMGGSPRPS--ITWLKDDSLLDIKENYKLEVFE 58

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKE 1940
                L    V   D+G YTC   N LG A  S    VQ ++
Sbjct: 59   QGQILQNSNVLKSDAGNYTCIGSNPLGNASHSFYFTVQERQ 99



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/97 (20%), Positives = 40/97 (41%)

Query: 4717 QADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNA 4776
            QA  +  L     I+   GQ  +    +    +P+I WL++ +L+    ++++       
Sbjct: 2    QAPFVTILNSTELILALTGQSRRLLCCMGGSPRPSITWLKDDSLLDIKENYKLEVFEQGQ 61

Query: 4777 VLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            +L   N  + D G +TC  +   G    S    V+ +
Sbjct: 62   ILQNSNVLKSDAGNYTCIGSNPLGNASHSFYFTVQER 98



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 2/64 (3%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAI 156
           G+P P ++W +  + L     Y +   EQ G + L    +   D G YTC   N  G A 
Sbjct: 31  GSPRPSITWLKDDSLLDIKENYKLEVFEQ-GQI-LQNSNVLKSDAGNYTCIGSNPLGNAS 88

Query: 157 CSVY 160
            S Y
Sbjct: 89  HSFY 92


>SB_58150| Best HMM Match : ig (HMM E-Value=3.7e-24)
          Length = 456

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 49/199 (24%), Positives = 79/199 (39%), Gaps = 9/199 (4%)

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            N+ + +G  ++L     G     V W + G +   + R ++++ D   TL ++E  P DS
Sbjct: 30   NITLLAGSTLKLRCPSDGLPKPFVKWTRYGVRAMSNER-QLIDSDSD-TLTMVEVLPYDS 87

Query: 4582 GKYECVAINSAGEARCDAECVV---SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
            G+  C   N  G  +  +   V     P+     +     +N  P  +            
Sbjct: 88   GEVSCTVTNLRGSDKKTSSITVLEPFAPSINTSDETVVSLSNLDPVTVRAGALLTTFLTT 147

Query: 4639 AIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSR-TADEYTLRISEAFPEDEGDYKCV 4696
             I   CK  G P P+V W + GDKL        M R +     + I++A P D G Y C 
Sbjct: 148  NITLVCKARGLPKPSVSWTRAGDKL--SHWLASMGRVSTSNGNVTITQAEPNDAGMYLCT 205

Query: 4697 AYNSAGRVTVAAKLKVTQP 4715
            A N  G  +  + L   +P
Sbjct: 206  ARNLLGVASARSTLYFKEP 224



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 52/190 (27%), Positives = 78/190 (41%), Gaps = 21/190 (11%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G   +  C   G P P V W      +R   N + L+ +S +  L +  V   DSG V+C
Sbjct: 36  GSTLKLRCPSDGLPKPFVKW--TRYGVRAMSNERQLI-DSDSDTLTMVEVLPYDSGEVSC 92

Query: 466 VARNKSGETAFQCRLNVIEK---------EQVVA-----PKFVERFSTLNVREGEPVVLN 511
              N  G       + V+E          E VV+     P  V   + L       + L 
Sbjct: 93  TVTNLRGSDKKTSSITVLEPFAPSINTSDETVVSLSNLDPVTVRAGALLTTFLTTNITLV 152

Query: 512 ARAVGTPTPRITWQKDGVPIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            +A G P P ++W + G  +        R+ T  G  T  I +A+ +DA  Y CTA+N+ 
Sbjct: 153 CKARGLPKPSVSWTRAGDKLSHWLASMGRVSTSNGNVT--ITQAEPNDAGMYLCTARNLL 210

Query: 570 GSTATRARLY 579
           G  + R+ LY
Sbjct: 211 GVASARSTLY 220



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 27/62 (43%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 94  KLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           K RG P P VSWTR    L        R +   G+V+  I Q  P D G Y CTARN  G
Sbjct: 154 KARGLPKPSVSWTRAGDKLSHWLASMGRVSTSNGNVT--ITQAEPNDAGMYLCTARNLLG 211

Query: 154 EA 155
            A
Sbjct: 212 VA 213



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 62/295 (21%), Positives = 114/295 (38%), Gaps = 22/295 (7%)

Query: 291 GNPRPRVTWFKNGQRLIN--SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIV 348
           G P+P V+W + G +L +  ++   + T++ + T  +   + +D+G Y   A N  G   
Sbjct: 157 GLPKPSVSWTRAGDKLSHWLASMGRVSTSNGNVT--ITQAEPNDAGMYLCTARNLLGVAS 214

Query: 349 TSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKM 408
               L  + P   ++  Q+         R  +  I  +   L    + +           
Sbjct: 215 ARSTLYFKEPRGPFIVTQKKSLTIFNATRPIDMTIGTNLTTLVNTTITIRCQASGDPAPD 274

Query: 409 TRFDCRVTGRPYPE-VTWFINDRQI--RDDYNHKILVNESGNHALM-ITNVTLSDSGVVT 464
           T +  R   +P+P+ VT    D  I        KI  ++    +L   TN+T++    ++
Sbjct: 275 TAWQ-RPGNKPFPKHVTIDREDLTIDMAPGLPPKITRSQEVITSLTRFTNLTVTIGSTIS 333

Query: 465 CVARNKSG-----ETAFQCRLN----VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV 515
            +A ++          F  ++N    VI +    AP      +TL    G  + +N +A 
Sbjct: 334 VLAGSRLKLLCPVTEPFGPKINSTRSVIIQLDSQAPITTMAGATLTTISGVDLTINCQAT 393

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           G P P + W  +G  +I    + +        L I  A  +D   Y CTA +  G
Sbjct: 394 GLPVPDVAWFLEGERVISQGGISVEN----GKLRIRNAGNADGGRYVCTANSSVG 444



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 4/66 (6%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
           G D     Q +G P P V WF  G+R+I+      I+  N   LR+RN   +D G Y   
Sbjct: 383 GVDLTINCQATGLPVPDVAWFLEGERVISQGG---ISVEN-GKLRIRNAGNADGGRYVCT 438

Query: 340 AENPNG 345
           A +  G
Sbjct: 439 ANSSVG 444



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 83/404 (20%), Positives = 134/404 (33%), Gaps = 41/404 (10%)

Query: 4435 DGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKC 4494
            DG P P +KW R       S + Q+    + ++ ++  +  +   V   V   RG   K 
Sbjct: 46   DGLPKPFVKWTRYGVRAM-SNERQLIDSDSDTLTMVEVLPYDSGEVSCTVTNLRGSDKKT 104

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR--LDTKVT------GTKPIDVY 4546
            S+  V+E                     V V +G L+   L T +T      G     V 
Sbjct: 105  SSITVLEPFAPSINTSDETVVSLSNLDPVTVRAGALLTTFLTTNITLVCKARGLPKPSVS 164

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W + G K+   + +          + I +A P D+G Y C A N  G A   +      P
Sbjct: 165  WTRAGDKLSHWLASMGRVSTSNGNVTITQAEPNDAGMYLCTARNLLGVASARSTLYFKEP 224

Query: 4607 ATK--DKPKPQTKAANAPPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLI 4663
                    K      NA   I   +   +       I   C+  G P P   W +     
Sbjct: 225  RGPFIVTQKKSLTIFNATRPIDMTIGTNLTTLVNTTITIRCQASGDPAPDTAWQRPGNKP 284

Query: 4664 KPSKYFQMSRTADEYTLRISEAFPE------------DEGDYKCVAYNSAGRVTVAAKLK 4711
             P K+  + R  ++ T+ ++   P                    V   S   V   ++LK
Sbjct: 285  FP-KHVTIDR--EDLTIDMAPGLPPKITRSQEVITSLTRFTNLTVTIGSTISVLAGSRLK 341

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQ------ITSKIKPTIQWLREGALIPETP 4765
            +  P      P +   R +++     A   T         S +  TI     G  +P+  
Sbjct: 342  LLCPVTEPFGPKINSTRSVIIQLDSQAPITTMAGATLTTISGVDLTINCQATGLPVPDVA 401

Query: 4766 DF----QMIHEG----NNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             F    ++I +G     N  L I N    D G + C A ++ G+
Sbjct: 402  WFLEGERVISQGGISVENGKLRIRNAGNADGGRYVCTANSSVGE 445



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 5/62 (8%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           +C+ TG P P+V WF+   ++       +   E+G   L I N   +D G   C A +  
Sbjct: 389 NCQATGLPVPDVAWFLEGERVISQGGISV---ENGK--LRIRNAGNADGGRYVCTANSSV 443

Query: 472 GE 473
           GE
Sbjct: 444 GE 445



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 1738 GDPKLRVEWLRNGVPIE----ASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            G PK  V W R G  +     +  R++T +  G V +      P D+G Y C A N LG 
Sbjct: 157  GLPKPSVSWTRAGDKLSHWLASMGRVSTSN--GNVTITQ--AEPNDAGMYLCTARNLLGV 212

Query: 1794 AVTSSTLFVQSKASLQLESQHES 1816
            A   STL+ +      + +Q +S
Sbjct: 213  ASARSTLYFKEPRGPFIVTQKKS 235


>SB_32327| Best HMM Match : ig (HMM E-Value=7.9e-23)
          Length = 932

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 46/138 (33%), Positives = 65/138 (47%), Gaps = 17/138 (12%)

Query: 431 QIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA 490
           ++  D+   I  N SG H   +  V   D+G  TCVA N+ G+      L+V  K   VA
Sbjct: 571 RVSGDHAKLIKKNRSGYHR--VCRVRREDAGNYTCVAENEFGKNTASVYLDV--KYPPVA 626

Query: 491 PKFVERFSTLNVREGEPVV-LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
                R +TL+V+EG  VV L+  A G P+PR+ W+K G   + + +           L 
Sbjct: 627 HV---RPATLSVQEGASVVSLSCDATGNPSPRVQWRKSGSDAVISSQ---------KVLV 674

Query: 550 IPRAKASDAAWYQCTAQN 567
           +      DA  YQCTA N
Sbjct: 675 LQNLTRLDAGVYQCTASN 692



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 18/168 (10%)

Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG- 472
           R +   YP VTW+         Y H  L   + N    I  VT +  GV  C   N  G 
Sbjct: 730 RCSTEAYPPVTWY-------KIYFHGQLQEVNDNGVYYIRKVTKAHEGVYHCEVSNLIGS 782

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
           +T+    ++V +K     P  V R +    + G+   L  +A G P P+ITW     P +
Sbjct: 783 DTSDLLFVDVKDK-----PAIVSRTTVFLSKVGKAAKLTCQADGYPLPQITWNPS--PPM 835

Query: 533 PNPELRI--HTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            N    +   T   A+ + +PR  A+D   Y+C+A+N  G++    +L
Sbjct: 836 GNTSYDVIGRTTVRATLIFVPR-NATDFGKYKCSARNENGNSTAIMQL 882



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 1/75 (1%)

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G+A + +C+  G PLP + W     +   S Y  + RT    TL        D G YKC 
Sbjct: 810  GKAAKLTCQADGYPLPQITWNPSPPMGNTS-YDVIGRTTVRATLIFVPRNATDFGKYKCS 868

Query: 4697 AYNSAGRVTVAAKLK 4711
            A N  G  T   +L+
Sbjct: 869  ARNENGNSTAIMQLR 883



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 15/117 (12%)

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEG-QPAQ 4739
            R+     ED G+Y CVA N  G+ T +  L V  P  A   PA      + V EG     
Sbjct: 589  RVCRVRREDAGNYTCVAENEFGKNTASVYLDVKYPPVAHVRPA-----TLSVQEGASVVS 643

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
                 T    P +QW + G+      D  +    +  VL++ N    D G + C A+
Sbjct: 644  LSCDATGNPSPRVQWRKSGS------DAVI---SSQKVLVLQNLTRLDAGVYQCTAS 691



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 1/60 (1%)

Query: 4110 PPVFVSLPDAVTVEEG-EWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHFD 4168
            PPV    P  ++V+EG       C  TG+P PRV W  +G+  V  S+  L    +   D
Sbjct: 623  PPVAHVRPATLSVQEGASVVSLSCDATGNPSPRVQWRKSGSDAVISSQKVLVLQNLTRLD 682



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 2/60 (3%)

Query: 265 PPKIAQKPRNSKLQEGADA-QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           PP    +P    +QEGA         +GNP PRV W K+G   + S++ +++   N T L
Sbjct: 623 PPVAHVRPATLSVQEGASVVSLSCDATGNPSPRVQWRKSGSDAVISSQ-KVLVLQNLTRL 681



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 2/69 (2%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           GK  +  C+  G P P++TW  N      + ++ ++   +    L+      +D G   C
Sbjct: 810 GKAAKLTCQADGYPLPQITW--NPSPPMGNTSYDVIGRTTVRATLIFVPRNATDFGKYKC 867

Query: 466 VARNKSGET 474
            ARN++G +
Sbjct: 868 SARNENGNS 876



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/53 (35%), Positives = 25/53 (47%)

Query: 3598 KPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            +P ++G   K I         +  V + DAG YTC A N  G+ T S  L VK
Sbjct: 569  EPRVSGDHAKLIKKNRSGYHRVCRVRREDAGNYTCVAENEFGKNTASVYLDVK 621



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 16/41 (39%), Positives = 25/41 (60%)

Query: 324 RVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
           RV   ++ D+G+YT +AEN  G    S YL V+ P  ++V+
Sbjct: 589 RVCRVRREDAGNYTCVAENEFGKNTASVYLDVKYPPVAHVR 629



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 9/91 (9%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            P + T T  N+      +V+L   V       + W+K+G     D+ N +  +     L 
Sbjct: 461  PGTITPTG-NITANQTDVVKLACHVNANPTPAIAWIKDG-----DVTNVLANQS---RLD 511

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            ++    Q  GKYEC ++N  G+   +   +V
Sbjct: 512  VVVEGKQTEGKYECYSLNLIGQGVAETNLIV 542



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 41/173 (23%), Positives = 68/173 (39%), Gaps = 29/173 (16%)

Query: 403 VTEG-KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           V EG  +    C  TG P P V W       R   +  ++   S    L++ N+T  D+G
Sbjct: 635 VQEGASVVSLSCDATGNPSPRVQW-------RKSGSDAVI---SSQKVLVLQNLTRLDAG 684

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT-- 519
           V  C A N         ++ V     V      +  +T+ +R G+ ++  + ++   T  
Sbjct: 685 VYQCTASN-------GVKIPVTNTSSVTV--IYKPSNTVLLRSGDVILTRSASLRCSTEA 735

Query: 520 -PRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            P +TW K    I  + +L+   D G     I +   +    Y C   N+ GS
Sbjct: 736 YPPVTWYK----IYFHGQLQEVNDNG--VYYIRKVTKAHEGVYHCEVSNLIGS 782


>SB_14261| Best HMM Match : ig (HMM E-Value=0)
          Length = 1337

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 68/266 (25%), Positives = 119/266 (44%), Gaps = 59/266 (22%)

Query: 4438 PLPL-IKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
            P+PL I WY++N  I                L I +V V+D   +     +  GT   ++
Sbjct: 555  PVPLQISWYKDNIFI-----------GLGKTLTISKVTVQDEGNYTCNVSSSCGTTLNTS 603

Query: 4497 NLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP 4556
             ++V+ K         P + TL+A   N   G++V+L+    G KP ++ ++        
Sbjct: 604  FIIVDYK---------PENTTLSANTTNACVGEMVQLNCSAVG-KPAEITYILK------ 647

Query: 4557 DIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT 4616
             +  K++ + G  +L+ L +   ++  + C+  N+AG  +   E  +++P ++       
Sbjct: 648  -MNGKLMSQTGV-SLVRLNSPVVNT--FACIPNNTAGSGQ---EATLNIPVSE------- 693

Query: 4617 KAANAPPEIIE-PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675
                 PP I++ P K+ I+ EG + E  C   G P P V WYK   L     Y  +S+ A
Sbjct: 694  -----PPSIVQFPSKNIILTEGDSKELMCNASGSPSPAVTWYK---LGIDWVYQNVSKLA 745

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSA 4701
                  +S    ED G Y+C+A N+A
Sbjct: 746  ------LSTR--EDTGSYRCMATNAA 763



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 64/285 (22%), Positives = 108/285 (37%), Gaps = 53/285 (18%)

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            N  +  G  V L    TG  P+ + W K+           I    G  TL I +   QD 
Sbjct: 537  NGRMVKGSSVTLTCDGTGPVPLQISWYKDN----------IFIGLGK-TLTISKVTVQDE 585

Query: 4582 GKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIE 4641
            G Y C   +S G     +  +V       KP+  T +AN     +          G+ ++
Sbjct: 586  GNYTCNVSSSCGTTLNTSFIIVDY-----KPENTTLSANTTNACV----------GEMVQ 630

Query: 4642 FSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
             +C  VGKP       K +  +       MS+T     +R++         + C+  N+A
Sbjct: 631  LNCSAVGKPAEITYILKMNGKL-------MSQTGVSL-VRLNSPVVNT---FACIPNNTA 679

Query: 4702 GRVTVAA-KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGAL 4760
            G    A   + V++P      P+    ++I++ EG   +     +    P + W + G  
Sbjct: 680  GSGQEATLNIPVSEPPSIVQFPS----KNIILTEGDSKELMCNASGSPSPAVTWYKLG-- 733

Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
                     +++  + + L   +  EDTG++ C AT AA    TS
Sbjct: 734  ------IDWVYQNVSKLAL---STREDTGSYRCMATNAAPCKNTS 769



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 13/91 (14%)

Query: 262 PVS-PPKIAQKP-RNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
           PVS PP I Q P +N  L EG   +     SG+P P VTW+K G   +  N  ++     
Sbjct: 690 PVSEPPSIVQFPSKNIILTEGDSKELMCNASGSPSPAVTWYKLGIDWVYQNVSKLAL--- 746

Query: 320 HTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
                   + + D+G Y  +A N   C  TS
Sbjct: 747 --------STREDTGSYRCMATNAAPCKNTS 769



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 31/126 (24%), Positives = 61/126 (48%), Gaps = 19/126 (15%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G+M + +C   G+P  E+T+ +         N K L++++G   + + +  ++      C
Sbjct: 626 GEMVQLNCSAVGKP-AEITYILK-------MNGK-LMSQTGVSLVRLNSPVVN---TFAC 673

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV--REGEPVVLNARAVGTPTPRIT 523
           +  N +G +  +  LN+   E    P  + +F + N+   EG+   L   A G+P+P +T
Sbjct: 674 IPNNTAG-SGQEATLNIPVSE----PPSIVQFPSKNIILTEGDSKELMCNASGSPSPAVT 728

Query: 524 WQKDGV 529
           W K G+
Sbjct: 729 WYKLGI 734



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 19/138 (13%)

Query: 437 NHKILVNESGNHALMITNVTLSDSG--VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
           N  I  N +G    +++N+ L+ SG  V TCV  N+ GE     +  ++   +V+    V
Sbjct: 479 NQTIKTNTNG----VLSNIKLNTSGEHVFTCVPTNEIGEGLN--KTVIVNASEVLPVVSV 532

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
           +      + +G  V L     G    +I+W KD + I           G   TL I +  
Sbjct: 533 DIPPNGRMVKGSSVTLTCDGTGPVPLQISWYKDNIFI-----------GLGKTLTISKVT 581

Query: 555 ASDAAWYQCTAQNVAGST 572
             D   Y C   +  G+T
Sbjct: 582 VQDEGNYTCNVSSSCGTT 599



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 15/82 (18%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD-ITHTYE 2840
            NI+  EGD+    CN   S              P P+ T YK   D+ Y ++  +  +  
Sbjct: 704  NIILTEGDSKELMCNASGS--------------PSPAVTWYKLGIDWVYQNVSKLALSTR 749

Query: 2841 EDSGIYTCKATNSKGSATTSGS 2862
            ED+G Y C ATN+     TS S
Sbjct: 750  EDTGSYRCMATNAAPCKNTSFS 771



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 4110 PPVFVSL-PDAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSRYKL 4159
            PP  V++ P + TV E +     C   G P P   W+   G+T+ +G  Y +
Sbjct: 2    PPSSVNITPPSPTVTERDQVNLTCSADGTPPPTFTWIRPQGHTVAHGPSYTI 53



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 15/95 (15%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDP-NLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            P+ +  + S  ++++G +V L       T P  L+I W+K+ +   +G  L         
Sbjct: 178  PVVSVDIPSNSRMIKGSNVTLTCD---GTGPVPLQISWYKDNIFKASGKNL--------- 225

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
              +I+ +   D G YTC  ++  G  ++T+ I ++
Sbjct: 226  --TISKVTVQDEGNYTCNVSSSCGTTLNTSFIGVD 258


>SB_15392| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 212

 Score = 56.4 bits (130), Expect = 5e-07
 Identities = 48/199 (24%), Positives = 91/199 (45%), Gaps = 7/199 (3%)

Query: 4223 QYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQ 4282
            Q Q  E E ++  E++Q +Q +     + E K +V +E + E Q+  K++  EE   K+Q
Sbjct: 12   QQQNQELEEQQQKEQKQEVQEE---QKQEEQKQEVQEEQKQEVQEEQKQEVQEEQKQKVQ 68

Query: 4283 ELENEQVIKESRLRESTHQYAIPGD--KVTSNTVAKSMAQRYEDNLDQT-EEVTEQRVQK 4339
            E + ++V KE +  E   Q     +  K       K   Q+ E   +Q  EE  EQ+ + 
Sbjct: 69   EEQKQEVQKEQKQEEQEEQKQEVQEEQKQEEQEEQKQEEQKQEVQEEQKQEEQEEQKQEV 128

Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQER 4399
            +  QK  + +  +  V  ++    +++Q Q+E    K+  ++    E  E E K + QE 
Sbjct: 129  QEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEEQEEQKQEEQEEQKQEVQE-EQKQEVQEE 187

Query: 4400 VVEGPVKPSKPPIFTKKMQ 4418
              +   +  K  +  +++Q
Sbjct: 188  QKQEVQEEQKQEVQKQEVQ 206



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 39/178 (21%), Positives = 81/178 (45%), Gaps = 6/178 (3%)

Query: 4231 LEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVI 4290
            + +T EE+Q  Q+Q       + K +  +  E + Q+  K++  EE   ++QE + ++V 
Sbjct: 1    MTRTKEEKQEEQQQNQELEEQQQKEQKQEVQEEQKQEEQKQEVQEEQKQEVQEEQKQEVQ 60

Query: 4291 KE--SRLRESTHQYAIPGDKVTSNTVAKSMA---QRYEDNLDQTEEVTEQRVQKKVTQKP 4345
            +E   +++E   Q      K       K      Q+ E+  +Q +E  +Q VQ++  Q+ 
Sbjct: 61   EEQKQKVQEEQKQEVQKEQKQEEQEEQKQEVQEEQKQEEQEEQKQEEQKQEVQEEQKQEE 120

Query: 4346 RIPDPSESTVHGK-EVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE 4402
            +     E     K EV   ++++ Q+E   + +  +K    E  + E + + ++ V E
Sbjct: 121  QEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEEQEEQKQEEQEEQKQEVQE 178



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/157 (19%), Positives = 75/157 (47%), Gaps = 5/157 (3%)

Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYY 4278
            +E  Q  + E + +   E++Q +Q++   + + E K +V +E + E Q+  K+++ ++  
Sbjct: 53   EEQKQEVQEEQKQKVQEEQKQEVQKEQKQEEQEEQKQEVQEEQKQEEQEEQKQEEQKQEV 112

Query: 4279 NKLQELENE----QVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTE 4334
             + Q+ E +    Q ++E + +E   +      +     V +   Q  ++   Q EE  E
Sbjct: 113  QEEQKQEEQEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEVQEEQKQEEQEEQKQ-EEQEE 171

Query: 4335 QRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKE 4371
            Q+ + +  QK  + +  +  V  ++    ++++ Q+E
Sbjct: 172  QKQEVQEEQKQEVQEEQKQEVQEEQKQEVQKQEVQEE 208


>SB_38293| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1732

 Score = 55.6 bits (128), Expect = 9e-07
 Identities = 80/344 (23%), Positives = 125/344 (36%), Gaps = 47/344 (13%)

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            S  F  V EN  GT K +A + +  K          PS T    N+ VT G LV L    
Sbjct: 461  SVQFTCVPENDVGTGK-NATVTINVK--------AAPSITFITANMTVTEGSLVNLQCNT 511

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
            +G+ P++V W K G          +L   G+     +    QD G Y+C+ +++  E R 
Sbjct: 512  SGSLPLNVSWSKVGAA-------GVLASSGSQEFSSI-TRAQD-GTYDCM-VHNGDECRA 561

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             ++ V        KP+  +   N               +G  + FSC    KP       
Sbjct: 562  ASQRVTI--TVNYKPENCSLTTNT--------SSNTYLKGDDVMFSCHAHSKPSTCNATL 611

Query: 4658 KGDKLIKPSKYFQ-MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPD 4716
              D     S   Q  S     + +   +    +   Y C   N AG+   +  L +  P 
Sbjct: 612  LHDGTSVTSLTDQTCSGLVTSHVMHNIQGCNAER--YSCRMSNVAGQCEESITLTINDPA 669

Query: 4717 QADNLPALTPLRD-----IVVYEGQPAQFKTQITSKIKPTIQWLREG--ALIPETPDFQM 4769
               ++ + TP  D     I + EG+        T    P I W ++G  A +      ++
Sbjct: 670  SV-HVTSTTPSGDTFASNITIIEGESLTLNCTATGCPTPNITWTKQGVSAALRSNITTEI 728

Query: 4770 IHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
            IH+       I +  + D G +TC A    G V  +  + V  K
Sbjct: 729  IHQ-------IASVQKSDAGRYTCAANNEIGAVSRTLSVTVHYK 765



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 38/125 (30%), Positives = 54/125 (43%), Gaps = 12/125 (9%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I +V   D+GV      N  G+T F+     ++   V+ P  V   + + V + +   
Sbjct: 108 LTIKDVQPQDAGVYAMRLANDDGKTTFEASKFTLD---VLVPPGVTPGANVTVNKTDKAE 164

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L+  A G PTP +TW + G   +          G   TL I   K SD   Y CTA N  
Sbjct: 165 LSCSATGNPTPNVTWTRSGGADVL---------GTGETLTISDVKISDGGCYVCTAYNNI 215

Query: 570 GSTAT 574
           GS A+
Sbjct: 216 GSEAS 220



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 5/76 (6%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S + + EGE + LN  A G PTP ITW K GV       +            I   + SD
Sbjct: 685 SNITIIEGESLTLNCTATGCPTPNITWTKQGVSAALRSNITTEI-----IHQIASVQKSD 739

Query: 558 AAWYQCTAQNVAGSTA 573
           A  Y C A N  G+ +
Sbjct: 740 AGRYTCAANNEIGAVS 755



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 35/115 (30%), Positives = 47/115 (40%), Gaps = 12/115 (10%)

Query: 3121 YSCRATNKWGQAEISVKLECVDKSK----GQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            YSCR +N  GQ E S+ L   D +        P   T   NI  + +G+S    CT    
Sbjct: 646  YSCRMSNVAGQCEESITLTINDPASVHVTSTTPSGDTFASNIT-IIEGESLTLNCTATGC 704

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              P+  I W   G      + I T      ++  IA  Q  D+G Y C A N+ G
Sbjct: 705  PTPN--ITWTKQGVSAALRSNITTE-----IIHQIASVQKSDAGRYTCAANNEIG 752



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 67/286 (23%), Positives = 98/286 (34%), Gaps = 44/286 (15%)

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP----DIRNKILEEDGTY---TLLILEA 4576
            N+T    + +       K +++ +L +G    P    D +++      T+   TL I + 
Sbjct: 54   NITPPATISVRVANIDVKGVNIGFLADGSPPMPIVYTDFKSRYSLSTATFNPITLTIKDV 113

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
             PQD+G Y     N  G+   +A                T     PP +  P  +  V +
Sbjct: 114  QPQDAGVYAMRLANDDGKTTFEASKF-------------TLDVLVPPGVT-PGANVTVNK 159

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
                E SC   G P P V W +       S    +  T +  TL IS+    D G Y C 
Sbjct: 160  TDKAELSCSATGNPTPNVTWTR-------SGGADVLGTGE--TLTISDVKISDGGCYVCT 210

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTI--QW 4754
            AYN+ G           Q   A N  A   +   +V +G              P I   +
Sbjct: 211  AYNNIGSEASGTVCLTVQ--YAPN--ATISVNTTLVCQGDHVALTCTAGDSFPPVIGYHF 266

Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
             R G LI        +   NN      +T   +   FTC A   AG
Sbjct: 267  YRGGTLI--------VTSSNNEYTAAASTGLPEFNEFTCAAYNLAG 304



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 7/87 (8%)

Query: 3704 NIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYAR 3763
            NI + EG  +  +C     G PT  I W   G   A  S + T      I   I  +   
Sbjct: 686  NITIIEGESLTLNCTA--TGCPTPNITWTKQGVSAALRSNITTE-----IIHQIASVQKS 738

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAK 3790
            DAG YTC A N+ G+ + T  +T   K
Sbjct: 739  DAGRYTCAANNEIGAVSRTLSVTVHYK 765



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 274 NSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDS 333
           N  + EG         +G P P +TW K G   +++     ITT      ++ + QKSD+
Sbjct: 686 NITIIEGESLTLNCTATGCPTPNITWTKQG---VSAALRSNITTE--IIHQIASVQKSDA 740

Query: 334 GHYTLLAENPNGCI 347
           G YT  A N  G +
Sbjct: 741 GRYTCAANNEIGAV 754



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 7/81 (8%)

Query: 2654 LVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSG 2713
            ++EG+ + L         PN  I W K GV+    A L+S     ++   I S++  D+G
Sbjct: 689  IIEGESLTLNCTATGCPTPN--ITWTKQGVS----AALRSNITTEIIH-QIASVQKSDAG 741

Query: 2714 IYTCKATNLLGEAVSTASIKI 2734
             YTC A N +G    T S+ +
Sbjct: 742  RYTCAANNEIGAVSRTLSVTV 762



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 5/65 (7%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W K G      S ITT      +   I SV   DAG YTC A N IG  + +
Sbjct: 703  GCPTPNITWTKQGVSAALRSNITT-----EIIHQIASVQKSDAGRYTCAANNEIGAVSRT 757

Query: 997  ANLTI 1001
             ++T+
Sbjct: 758  LSVTV 762



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 16/38 (42%), Positives = 21/38 (55%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
            PS T    N+ VT G LV L    +G+ P++V W K G
Sbjct: 1024 PSITFITANMTVTEGSLVNLQCNTSGSPPLNVSWSKVG 1061



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 34/132 (25%), Positives = 52/132 (39%), Gaps = 15/132 (11%)

Query: 436  YNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE 495
            Y +  +V+ES    + + + TL+     TCV  N  G T     +++        P+   
Sbjct: 1577 YRNDDVVDESAT-GMFVISPTLAGDNAYTCVPNNTLG-TGQNSSVHITT---TAPPRIHG 1631

Query: 496  RFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKA 555
              S L V EG  V L   A G+    +TW+       PN            TL++     
Sbjct: 1632 ITSDLTVTEGSDVALQCNATGSEPLNVTWRS------PNGAFL----SSGVTLNLNILSR 1681

Query: 556  SDAAWYQCTAQN 567
            +D   YQC+A N
Sbjct: 1682 NDEGSYQCSASN 1693



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 11/151 (7%)

Query: 382  RIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKIL 441
            +I + +K  A QF     D    +G+     C  + +P      F  +  I  +Y     
Sbjct: 1189 QIAVKDKPEATQFSLNTSDGAYLKGEPVSLYCNSSAKPALCHVVFRKNDVIIKNYTSDTC 1248

Query: 442  VNESGNHALMITNVTLSDSGVVTCVARNKSG---ETAFQCRLN---VIEKEQVVAPKFVE 495
               S +H  +I++V   D    +C A N +G   E  +   +     I       P+  +
Sbjct: 1249 ---SASH--LISSVEGCDRESFSCQAFNIAGTGDEVFYNATIQDAPAIISVMSQTPQGPK 1303

Query: 496  RFSTLNVREGEPVVLNARAVGTPTPRITWQK 526
              S++ + EGE + LN  A G P P ITW K
Sbjct: 1304 AASSIALLEGETLTLNCTASGCPAPNITWYK 1334



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 16/38 (42%), Positives = 21/38 (55%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
            PS T    N+ VT G LV L    +G+ P++V W K G
Sbjct: 852  PSITFINANMTVTEGSLVNLQCNTSGSLPLNVSWSKVG 889



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           + EG+    +C  TG P P +TW       +   +  +  N +      I +V  SD+G 
Sbjct: 689 IIEGESLTLNCTATGCPTPNITW------TKQGVSAALRSNITTEIIHQIASVQKSDAGR 742

Query: 463 VTCVARNKSG 472
            TC A N+ G
Sbjct: 743 YTCAANNEIG 752



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 6/81 (7%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W + GV     + +TT      +   +  V   D+G YTC A NE+G    +
Sbjct: 703  GCPTPNITWTKQGVSAALRSNITTE-----IIHQIASVQKSDAGRYTCAANNEIGAVSRT 757

Query: 1798 STLFVQSK-ASLQLESQHESA 1817
             ++ V  K  + QL S   SA
Sbjct: 758  LSVTVHYKPINTQLTSTKTSA 778



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 16/41 (39%), Positives = 21/41 (51%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            VTV + + A   C  TG+P P V W  +G   V G+   LT
Sbjct: 155  VTVNKTDKAELSCSATGNPTPNVTWTRSGGADVLGTGETLT 195



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 7/82 (8%)

Query: 72  PIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSL 131
           P  +    N    +G +        G PTP ++WT++          ++R N  T ++  
Sbjct: 678 PSGDTFASNITIIEGESLTLNCTATGCPTPNITWTKQGVSA------ALRSNITT-EIIH 730

Query: 132 LIKQIGPGDEGEYTCTARNQYG 153
            I  +   D G YTC A N+ G
Sbjct: 731 QIASVQKSDAGRYTCAANNEIG 752



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query: 969  LTIKSVTVHDAGHYTCRAYNAIG-QATTSANLTI 1001
            LTI  V + D G Y C AYN IG +A+ +  LT+
Sbjct: 194  LTISDVKISDGGCYVCTAYNNIGSEASGTVCLTV 227



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 9/88 (10%)

Query: 645 SVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQ 704
           ++T +EG  +         G PT  I W K G S    S  T+      I   + S+   
Sbjct: 686 NITIIEGESLTLNCTA--TGCPTPNITWTKQGVSAALRSNITT-----EIIHQIASVQKS 738

Query: 705 DSGEYTCRAVSATG-VAETKAV-LHVTP 730
           D+G YTC A +  G V+ T +V +H  P
Sbjct: 739 DAGRYTCAANNEIGAVSRTLSVTVHYKP 766



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 5/68 (7%)

Query: 795 TPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEA 854
           T    PT  + W K G      S IT+      +   I  ++  DAG YT  A N++G  
Sbjct: 700 TATGCPTPNITWTKQGVSAALRSNITT-----EIIHQIASVQKSDAGRYTCAANNEIGAV 754

Query: 855 ISTASIRV 862
             T S+ V
Sbjct: 755 SRTLSVTV 762



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 14/45 (31%), Positives = 22/45 (48%)

Query: 385  ISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIND 429
            IS  +  PQ  K      + EG+    +C  +G P P +TW+ +D
Sbjct: 1292 ISVMSQTPQGPKAASSIALLEGETLTLNCTASGCPAPNITWYKHD 1336



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 30/111 (27%), Positives = 44/111 (39%), Gaps = 12/111 (10%)

Query: 4616 TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTA 4675
            T  A  PP I      + VAEG  +   C   G   P +        I+ +   Q+S T 
Sbjct: 312  TVQAKVPPAITGFSPPQNVAEGSEVMLECNATGSS-PNIT-------IERNGEAQLSTTG 363

Query: 4676 DEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP 4726
                  IS     +EG Y+C+ +N     TV +   +T   + +N   LTP
Sbjct: 364  KHTFAAISR---REEGSYRCIVHNGGECPTVYSTTNITVNYKPEN-TTLTP 410



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 7/84 (8%)

Query: 1319 NIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPE 1378
            NI  +EG ++ L C     G  T  + W   G  +    R     E  +    + SV   
Sbjct: 686  NITIIEGESLTLNCTA--TGCPTPNITWTKQG--VSAALRSNITTEIIH---QIASVQKS 738

Query: 1379 DSGVYTCQATNQLGEAVTSCALRV 1402
            D+G YTC A N++G    + ++ V
Sbjct: 739  DAGRYTCAANNEIGAVSRTLSVTV 762


>SB_29770| Best HMM Match : ig (HMM E-Value=3.4e-05)
          Length = 454

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 10/167 (5%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           EG  T   C+VTG+ +   T  +      D  N   + +    H ++I +V  +D+G+  
Sbjct: 250 EGSRTNISCQVTGQAFIMWTTPLGHSVPYDRTNRLYVFSNGFRHDVIIESVNRTDAGLYR 309

Query: 465 CVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           C     S       RL V    +++  +   + +  N  + +P+ LN    G P P +  
Sbjct: 310 CYGNTDSKAV----RLEVEYAPELIQSESTTQVTWSNYADRDPIELNCTFDGFPVPTVEL 365

Query: 525 QKDGVPIIPNPELRIHTDGGASTLDIPRAKASD-AAWYQCTAQNVAG 570
            KD   I  +      T G  S +   RAK+ +   +YQCTA+N  G
Sbjct: 366 YKDSKVITSHV-----TKGRGSLVYKARAKSIEYYGFYQCTARNTQG 407



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694
            A+   IE +C   G P+PTV+ YK  K+I  + +    R +  Y  R      E  G Y+
Sbjct: 344  ADRDPIELNCTFDGFPVPTVELYKDSKVI--TSHVTKGRGSLVYKARAKSI--EYYGFYQ 399

Query: 4695 CVAYNSAGRVT 4705
            C A N+ G VT
Sbjct: 400  CTARNTQGEVT 410


>SB_54662| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 673

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 47/168 (27%), Positives = 63/168 (37%), Gaps = 8/168 (4%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
           G  T   C + G P P + W    +QI     H     ++G   L+I      D G   C
Sbjct: 112 GWETTLTCDIFGFPPPHIEWTRALQQI-----HSGRTRQAGRR-LIIKKTEQQDRGPYMC 165

Query: 466 VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ 525
              NK G       L V         K      T+  R G  + L   A G+PTP I W 
Sbjct: 166 TGTNKLGSVFALIVLTVYPVVPPTITKSPPPVVTVQ-RRGATLQLTCAAQGSPTPTIEWS 224

Query: 526 KDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
           KDG  +I   + R   +    +L +P  +  D   YQC  +N    TA
Sbjct: 225 KDG-RLISTNDSRSEANTREGSLVMPYFQPEDQGDYQCFFRNFDNGTA 271



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 13/129 (10%)

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L+I +   QD G Y C   N  G        ++ L      P   TK+   PP ++    
Sbjct: 150  LIIKKTEQQDRGPYMCTGTNKLGSVFA----LIVLTVYPVVPPTITKS---PPPVVT--- 199

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
              +   G  ++ +C   G P PT++W K  +LI  +     + T  E +L +    PED+
Sbjct: 200  --VQRRGATLQLTCAAQGSPTPTIEWSKDGRLISTNDSRSEANTR-EGSLVMPYFQPEDQ 256

Query: 4691 GDYKCVAYN 4699
            GDY+C   N
Sbjct: 257  GDYQCFFRN 265



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 40/157 (25%), Positives = 56/157 (35%), Gaps = 7/157 (4%)

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G     +C I G P P ++W +  + I   +  Q  R      L I +   +D G Y C 
Sbjct: 112  GWETTLTCDIFGFPPPHIEWTRALQQIHSGRTRQAGR-----RLIIKKTEQQDRGPYMCT 166

Query: 4697 AYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR 4756
              N  G V     L V  P     +    P    V   G   Q          PTI+W +
Sbjct: 167  GTNKLGSVFALIVLTV-YPVVPPTITKSPPPVVTVQRRGATLQLTCAAQGSPTPTIEWSK 225

Query: 4757 EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTC 4793
            +G LI  T D +         L++     ED G + C
Sbjct: 226  DGRLI-STNDSRSEANTREGSLVMPYFQPEDQGDYQC 261



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 3/83 (3%)

Query: 262 PVSPPKIAQKPRN--SKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN 319
           PV PP I + P    +  + GA  Q      G+P P + W K+G RLI++N         
Sbjct: 184 PVVPPTITKSPPPVVTVQRRGATLQLTCAAQGSPTPTIEWSKDG-RLISTNDSRSEANTR 242

Query: 320 HTTLRVRNTQKSDSGHYTLLAEN 342
             +L +   Q  D G Y     N
Sbjct: 243 EGSLVMPYFQPEDQGDYQCFFRN 265



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 3/66 (4%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           +G   +     +G+PTP + W+ K   L+  N      N + G  SL++    P D+G+Y
Sbjct: 203 RGATLQLTCAAQGSPTPTIEWS-KDGRLISTNDSRSEANTREG--SLVMPYFQPEDQGDY 259

Query: 145 TCTARN 150
            C  RN
Sbjct: 260 QCFFRN 265



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 54/216 (25%), Positives = 74/216 (34%), Gaps = 27/216 (12%)

Query: 499 TLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTL--DIPRAKAS 556
           TL  ++G+ + +   A G P P I W  DG P  P P       G  +TL  DI      
Sbjct: 70  TLVAKQGQNLKIPCIATGFPEPVIAWSHDGKP--PPPVYLPGYIGWETTLTCDIFGFPPP 127

Query: 557 DAAWYQCTAQNVAGSTATRARLYXXXXXXXXXXQKRLHLPRPTKVXXXXXXXXXXXXYLR 616
              W +   Q  +G T    R             +  ++   T              Y  
Sbjct: 128 HIEWTRALQQIHSGRTRQAGR--RLIIKKTEQQDRGPYMCTGTNKLGSVFALIVLTVY-- 183

Query: 617 HVERARPYIPPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNG 676
                 P +PP       PPP   V  +  T         +      G PT  IEW K+G
Sbjct: 184 ------PVVPPTITKS--PPPVVTVQRRGAT--------LQLTCAAQGSPTPTIEWSKDG 227

Query: 677 QSIEAS-SRFTSIFRFGYISLDMLSLNIQDSGEYTC 711
           + I  + SR  +  R G  SL M     +D G+Y C
Sbjct: 228 RLISTNDSRSEANTREG--SLVMPYFQPEDQGDYQC 261



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/71 (35%), Positives = 30/71 (42%), Gaps = 7/71 (9%)

Query: 2131 CRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKL 2190
            C +     PH  I+W    Q+I +G     T   G   L I  T  +D G YMC  TNKL
Sbjct: 119  CDIFGFPPPH--IEWTRALQQIHSGR----TRQAGR-RLIIKKTEQQDRGPYMCTGTNKL 171

Query: 2191 GEAVNTCTLKV 2201
            G       L V
Sbjct: 172  GSVFALIVLTV 182



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 14/109 (12%)

Query: 54  SSGDRQPITA-GRPGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPL 112
           ++G  +P+ A    G+P PP++   +       G        + G P P + WTR    +
Sbjct: 85  ATGFPEPVIAWSHDGKPPPPVYLPGYI------GWETTLTCDIFGFPPPHIEWTRALQQI 138

Query: 113 VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
                +S R   Q G   L+IK+    D G Y CT  N+ G     + +
Sbjct: 139 -----HSGR-TRQAGR-RLIIKKTEQQDRGPYMCTGTNKLGSVFALIVL 180



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 13/89 (14%)

Query: 2365 PEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLI--EDS 2422
            P +P  +T+  P    P+  +   + G T    C     G PT  +EW ++ +LI   DS
Sbjct: 184  PVVPPTITKSPP----PVVTVQ--RRGATLQLTCAA--QGSPTPTIEWSKDGRLISTNDS 235

Query: 2423 SRITKTHDFGYVSMTISHVRDEDEGVYMC 2451
                 T +    S+ + + + ED+G Y C
Sbjct: 236  RSEANTRE---GSLVMPYFQPEDQGDYQC 261


>SB_29852| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 836

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 54/230 (23%), Positives = 92/230 (40%), Gaps = 21/230 (9%)

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
            +GKY+C A +++G  R D     ++   ++ P    + + AP    E  K+ +V     +
Sbjct: 311  AGKYKCKATDTSG--RTDTS--TTIVRMEETPAGFGQGSRAP----EASKNALV--DSTV 360

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
               C+  G P P V+W KG   +     +Q   + D   L+IS     D G Y C   N 
Sbjct: 361  TLHCQPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNR 417

Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSK--IKPTIQWLREG 4758
             G  +   +L V      D +    P  + +   G   +F   +T+    +   QW R  
Sbjct: 418  LGSASRTGRLNV-----QDKIAVTHPPDNKIATVGGTVRFTCGVTTSGVTEVVFQWRRFV 472

Query: 4759 ALIPETPDFQMIHEGNNAVLL-IGNTYEEDTGTFTCRATTAAGQVETSAK 4807
             L+  +    M   G     L I      D G + C+AT +  + + S++
Sbjct: 473  FLLQPSSRISMGKIGEQTGFLEIRGVEFSDQGLYACKATGSIQKDDASSE 522



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 57/229 (24%), Positives = 89/229 (38%), Gaps = 17/229 (7%)

Query: 356 ESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTE----GKMTRF 411
           +S +  YV    +  I   Q R     + +  + L PQ  KV  +  VT+    G+    
Sbjct: 210 QSDSGDYVCTVTNNNINKQQVRTVVLNV-MPVRPLIPQPPKVSTEFSVTKIALKGERFVL 268

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGN-HALMITNVTLSDSGVVTCVARNK 470
           +C V G P P++T       +R    H IL   +GN     I   T + +G   C A + 
Sbjct: 269 ECIVYGMPVPKIT-------LRKKGVHMILGQVTGNARRHYIPKFTANHAGKYKCKATDT 321

Query: 471 SGETAFQCRLNVIEKEQVVAPKFVER-FSTLNVREGEPVVLNARAVGTPTPRITWQKDGV 529
           SG T     +  +E+      +      ++ N      V L+ +  G P P + W+K  V
Sbjct: 322 SGRTDTSTTIVRMEETPAGFGQGSRAPEASKNALVDSTVTLHCQPSGNPKPMVRWRKGSV 381

Query: 530 PIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +   P  +  T G    L I    + D+  Y C   N  GS +   RL
Sbjct: 382 YLSSGPRYQFLTSG---DLKISNVTSLDSGRYTCEVSNRLGSASRTGRL 427



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 54/239 (22%), Positives = 93/239 (38%), Gaps = 23/239 (9%)

Query: 4580 DSGKYEC-VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQ 4638
            DSG Y C V  N+  + +     +  +P     P+P       P    E    KI  +G+
Sbjct: 212  DSGDYVCTVTNNNINKQQVRTVVLNVMPVRPLIPQP-------PKVSTEFSVTKIALKGE 264

Query: 4639 AIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA 4697
                 C + G P+P +   K G  +I      Q++  A  +   I +      G YKC A
Sbjct: 265  RFVLECIVYGMPVPKITLRKKGVHMILG----QVTGNARRHY--IPKFTANHAGKYKCKA 318

Query: 4698 YNSAGRV---TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
             +++GR    T   +++ T         A    ++ +V          Q +   KP ++W
Sbjct: 319  TDTSGRTDTSTTIVRMEETPAGFGQGSRAPEASKNALV--DSTVTLHCQPSGNPKPMVRW 376

Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
             +    +   P +Q +  G+   L I N    D+G +TC  +   G    + +L V+ K
Sbjct: 377  RKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSASRTGRLNVQDK 432



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYR--TSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
            +P  +P   V W      L SG RY+  TS D     L I  V   DSG YTC+  N LG
Sbjct: 365  QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD-----LKISNVTSLDSGRYTCEVSNRLG 419

Query: 1927 QAVSSIRLNVQSKESIIRDSQHESA 1951
             A  + RLNVQ K ++     ++ A
Sbjct: 420  SASRTGRLNVQDKIAVTHPPDNKIA 444



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 2667 EPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA 2726
            +P  +P   + W K  V L++G R +      L   ++ SL   DSG YTC+ +N LG A
Sbjct: 365  QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGDLKISNVTSL---DSGRYTCEVSNRLGSA 421

Query: 2727 VSTASIKIEDR 2737
              T  + ++D+
Sbjct: 422  SRTGRLNVQDK 432



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 50/192 (26%), Positives = 77/192 (40%), Gaps = 22/192 (11%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCS 4495
            G P P+++W + +  + + P +Q   F T   L I  V   DS  +     NR G+A  +
Sbjct: 368  GNPKPMVRWRKGSVYLSSGPRYQ---FLTSGDLKISNVTSLDSGRYTCEVSNRLGSASRT 424

Query: 4496 ANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVT--GTKPIDVYWLKNGKK 4553
              L V++K           + T    N   T G  VR    VT  G   +   W +    
Sbjct: 425  GRLNVQDK----------IAVTHPPDNKIATVGGTVRFTCGVTTSGVTEVVFQWRRFVFL 474

Query: 4554 VQPDIR---NKILEEDGTYTLLILEAYPQDSGKYECVAINS--AGEARCDAECVVSLPAT 4608
            +QP  R    KI E+ G   +  +E    D G Y C A  S    +A  +A  ++++   
Sbjct: 475  LQPSSRISMGKIGEQTGFLEIRGVEF--SDQGLYACKATGSIQKDDASSEAFALLNVQGA 532

Query: 4609 KDKPKPQTKAAN 4620
             +KP   T   N
Sbjct: 533  PEKPHGVTILPN 544



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 4/79 (5%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C+ +G P P V W      +     ++ L   SG+  L I+NVT  DSG  TC   N+ G
Sbjct: 364 CQPSGNPKPMVRWRKGSVYLSSGPRYQFLT--SGD--LKISNVTSLDSGRYTCEVSNRLG 419

Query: 473 ETAFQCRLNVIEKEQVVAP 491
             +   RLNV +K  V  P
Sbjct: 420 SASRTGRLNVQDKIAVTHP 438



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 288 QLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
           Q SGNP+P V W K    L +  +++ +T+ +   L++ N    DSG YT    N  G  
Sbjct: 365 QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSA 421

Query: 348 VTSGYLAVE 356
             +G L V+
Sbjct: 422 SRTGRLNVQ 430



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 14/163 (8%)

Query: 3074 PTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAE 3133
            P+G+   ++ W      + +  R + + +     L+I    + DSG Y+C  +N+ G A 
Sbjct: 366  PSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSAS 422

Query: 3134 ISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMR 3193
             + +L   DK         TH  + +    G +  F C V      ++  +W      ++
Sbjct: 423  RTGRLNVQDKIA------VTHPPDNKIATVGGTVRFTCGVTTSGVTEVVFQWRRFVFLLQ 476

Query: 3194 HSTRI---KTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
             S+RI   K     GF  L+I   +  D G Y C+A     +D
Sbjct: 477  PSSRISMGKIGEQTGF--LEIRGVEFSDQGLYACKATGSIQKD 517



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 3/66 (4%)

Query: 2798 EPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSA 2857
            +PS +P   + W   +  L SG RY+     +   L I++    DSG YTC+ +N  GSA
Sbjct: 365  QPSGNPKPMVRWRKGSVYLSSGPRYQF---LTSGDLKISNVTSLDSGRYTCEVSNRLGSA 421

Query: 2858 TTSGSL 2863
            + +G L
Sbjct: 422  SRTGRL 427



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 1736 PVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAV 1795
            P G+PK  V W +  V + +  R   +       L +  V   DSG YTC   N LG A 
Sbjct: 366  PSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSAS 422

Query: 1796 TSSTLFVQSKASL 1808
             +  L VQ K ++
Sbjct: 423  RTGRLNVQDKIAV 435



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 3/71 (4%)

Query: 3720 EPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSA 3779
            +P G+P   + W       ++G R   L       L I  + + D+G YTC  +N+ GSA
Sbjct: 365  QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTCEVSNRLGSA 421

Query: 3780 TTTAKITCSAK 3790
            + T ++    K
Sbjct: 422  SRTGRLNVQDK 432



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 5/90 (5%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            + L C  +P G+P   V W      ++ G R++ +   G   L I + TS D+G YT   
Sbjct: 360  VTLHC--QPSGNPKPMVRWRKGSVYLSSGPRYQ-FLTSG--DLKISNVTSLDSGRYTCEV 414

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTDTQNEQA 1284
             N LGSA  +  + V ++  +     N+ A
Sbjct: 415  SNRLGSASRTGRLNVQDKIAVTHPPDNKIA 444



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 3/70 (4%)

Query: 3446 PTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAV 3505
            P+ +P   V W      L +G R++ F   G   L+IS     DSG Y C   N  G A 
Sbjct: 366  PSGNPKPMVRWRKGSVYLSSGPRYQ-FLTSGD--LKISNVTSLDSGRYTCEVSNRLGSAS 422

Query: 3506 TTASMKVQGK 3515
             T  + VQ K
Sbjct: 423  RTGRLNVQDK 432



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 5/87 (5%)

Query: 4619 ANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
            + + P+II   KD +V  G +    C  +     TV WY     I       M ++ D  
Sbjct: 46   STSKPQIIVGPKDTLV-HGTSFTLMC--IATKDSTVTWYHDGNRIDFQWQTNMQQSKDG- 101

Query: 4679 TLRISEAFPE-DEGDYKCVAYNSAGRV 4704
            +L +S A    D+G Y+CV  NS G +
Sbjct: 102  SLHVSNAISSRDKGPYRCVVSNSRGTI 128



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 39/165 (23%), Positives = 66/165 (40%), Gaps = 16/165 (9%)

Query: 3071 SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
            +L+    +   + W+++G  I+   +     +    +       + D G Y C  +N  G
Sbjct: 67   TLMCIATKDSTVTWYHDGNRIDFQWQTNMQQSKDGSLHVSNAISSRDKGPYRCVVSNSRG 126

Query: 3131 QAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNG- 3189
               IS +     K     P   T+   + G ++  SA   C   P   PD +I+W     
Sbjct: 127  TI-ISRRANV--KFPYLMPFAVTNF--VIGKEESHSAVLHCQA-PDSYPDRQIQWSKQDP 180

Query: 3190 ------QPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYN 3228
                  +P+  S++  T+S  G   L  AY +  DSG+YVC   N
Sbjct: 181  NFPGRRRPLPQSSKY-TISSEGD--LHFAYLEQSDSGDYVCTVTN 222



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 10/82 (12%)

Query: 2916 PIAAEHQLVEGQV-LHLEGQVEPKNDPDLKIEWYFNGKVLEQGSRFK-LTSDFGFVTLDL 2973
            P A+++ LV+  V LH +    P  +P   + W      L  G R++ LTS      L +
Sbjct: 348  PEASKNALVDSTVTLHCQ----PSGNPKPMVRWRKGSVYLSSGPRYQFLTSG----DLKI 399

Query: 2974 VDVYERDSGIYTCKAYNKRGEA 2995
             +V   DSG YTC+  N+ G A
Sbjct: 400  SNVTSLDSGRYTCEVSNRLGSA 421



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 1326 TNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTC 1385
            + V L C  QP G+    V W      + +G R++     D   L + +V   DSG YTC
Sbjct: 358  STVTLHC--QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYTC 412

Query: 1386 QATNQLGEAVTSCALRV 1402
            + +N+LG A  +  L V
Sbjct: 413  EVSNRLGSASRTGRLNV 429



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 3/71 (4%)

Query: 934  EPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA 993
            +P G+    V W K    + +  R   F   G   L I +VT  D+G YTC   N +G A
Sbjct: 365  QPSGNPKPMVRWRKGSVYLSSGPRYQ-FLTSG--DLKISNVTSLDSGRYTCEVSNRLGSA 421

Query: 994  TTSANLTIVTK 1004
            + +  L +  K
Sbjct: 422  SRTGRLNVQDK 432



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%)

Query: 3572 NSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYT 3631
            +S+    C+  P  +    V W      L +G R + +       L+I  V   D+G YT
Sbjct: 357  DSTVTLHCQ--PSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD---LKISNVTSLDSGRYT 411

Query: 3632 CKATNRHGEATVSCKLQVKGRQGIILEP 3659
            C+ +NR G A+ + +L V+ +  +   P
Sbjct: 412  CEVSNRLGSASRTGRLNVQDKIAVTHPP 439



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 5/59 (8%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           GNP P+V W +    L    +Y       +GD  L I  +   D G YTC   N+ G A
Sbjct: 368 GNPKPMVRWRKGSVYLSSGPRYQFL---TSGD--LKISNVTSLDSGRYTCEVSNRLGSA 421



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 3/58 (5%)

Query: 3854 EPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            +P  +PK  + W +    L SG RY+ +       L I  V + DSG Y C   N  G
Sbjct: 365  QPSGNPKPMVRWRKGSVYLSSGPRYQFLTS---GDLKISNVTSLDSGRYTCEVSNRLG 419



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 7/70 (10%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYR--TTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            +P  +P   + W      + +G RY+  T+ D     L I    + DSG Y C+ +N+LG
Sbjct: 365  QPSGNPKPMVRWRKGSVYLSSGPRYQFLTSGD-----LKISNVTSLDSGRYTCEVSNRLG 419

Query: 2192 EAVNTCTLKV 2201
             A  T  L V
Sbjct: 420  SASRTGRLNV 429


>SB_16673| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 529

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 53/202 (26%), Positives = 81/202 (40%), Gaps = 26/202 (12%)

Query: 389 ALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           +L  Q+V V   + +   K    +CR TG P P++ W   + ++  D   K+      N 
Sbjct: 129 SLQKQYVLV---QSIKSPKDLIINCRATGYPTPQIIWTRYNGKLSADRTRKM-----PNG 180

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508
            L+I+  T  D G  +C+  N+ G       ++V+E      PK + + +  +   GE  
Sbjct: 181 TLVISKATRGDGGAYSCLVTNELGRDLKNFTVSVLEP-----PKILGK-TEFHFNVGETA 234

Query: 509 VLNARAVGTPTPRITWQ-----------KDGVPIIPNPELRIHTDGGA-STLDIPRAKAS 556
            L  ++ G P P +TW            KDG            TD    STL I    A 
Sbjct: 235 KLFCKSRGNPPPAVTWSWKDIDNKTVILKDGEDDSRRRVAITDTDDFVVSTLTIDSVTAD 294

Query: 557 DAAWYQCTAQNVAGSTATRARL 578
           D   Y+C A+N  G  A    L
Sbjct: 295 DWKTYRCIAKNKFGDDAENIAL 316



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 9/81 (11%)

Query: 2778 SHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNN------KPLP-SGTRY--KSTHDF 2828
            S L N+  KEG++    C + P  +P   I WF  N      + +P S T+Y  ++    
Sbjct: 21   SELQNVTVKEGEDAILPCALPPRVEPKYLITWFMGNAKYLTKRMMPTSTTKYIDRAMEID 80

Query: 2829 SYVSLDITHTYEEDSGIYTCK 2849
            S  +L +  T  ED+G Y+CK
Sbjct: 81   SQDALVLRKTVREDTGTYSCK 101



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 38/185 (20%), Positives = 78/185 (42%), Gaps = 17/185 (9%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPE--VTWFIND-----RQIRDDYNHKIL---VNESGNH 448
           Q+  V EG+     C +  R  P+  +TWF+ +     +++      K +   +      
Sbjct: 24  QNVTVKEGEDAILPCALPPRVEPKYLITWFMGNAKYLTKRMMPTSTTKYIDRAMEIDSQD 83

Query: 449 ALMITNVTLSDSGVVTC--VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL-NVREG 505
           AL++      D+G  +C  +    S +TA    +  ++   V+     +++  + +++  
Sbjct: 84  ALVLRKTVREDTGTYSCKVLYYGPSMQTAAAQIMLFVKGPPVITSSLQKQYVLVQSIKSP 143

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
           + +++N RA G PTP+I W +    +  +   ++       TL I +A   D   Y C  
Sbjct: 144 KDLIINCRATGYPTPQIIWTRYNGKLSADRTRKMPN----GTLVISKATRGDGGAYSCLV 199

Query: 566 QNVAG 570
            N  G
Sbjct: 200 TNELG 204



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 68/288 (23%), Positives = 108/288 (37%), Gaps = 46/288 (15%)

Query: 4437 EPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSA 4496
            EP  LI W+  N   K      + T +TK I    ++  +D+ V         GT  C  
Sbjct: 45   EPKYLITWFMGN--AKYLTKRMMPTSTTKYIDRAMEIDSQDALVLRKTVREDTGTYSCKV 102

Query: 4497 NLVVEEKRRQGRGGIV-----PPSFTLTAQNV-----NVTSGQLVRLDTKVTGTKPIDVY 4546
             L      +     I+     PP  T + Q       ++ S + + ++ + TG     + 
Sbjct: 103  -LYYGPSMQTAAAQIMLFVKGPPVITSSLQKQYVLVQSIKSPKDLIINCRATGYPTPQII 161

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W +   K+  D   K+   +GT  L+I +A   D G Y C+  N  G             
Sbjct: 162  WTRYNGKLSADRTRKM--PNGT--LVISKATRGDGGAYSCLVTNELG------------- 204

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD-----K 4661
              +D  K  T +   PP+I+   +      G+  +  CK  G P P V W   D      
Sbjct: 205  --RDL-KNFTVSVLEPPKILGKTEFHFNV-GETAKLFCKSRGNPPPAVTWSWKDIDNKTV 260

Query: 4662 LIKPSKYFQMSRTA----DEY---TLRISEAFPEDEGDYKCVAYNSAG 4702
            ++K  +     R A    D++   TL I     +D   Y+C+A N  G
Sbjct: 261  ILKDGEDDSRRRVAITDTDDFVVSTLTIDSVTADDWKTYRCIAKNKFG 308



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 46/196 (23%), Positives = 75/196 (38%), Gaps = 21/196 (10%)

Query: 3058 VDISEGQIAHYEASLIPTGDQSMVIEWFY-NGK--------TIEASHRIRTVYAFGMVVL 3108
            V + EG+ A    +L P  +   +I WF  N K        T    +  R +       L
Sbjct: 26   VTVKEGEDAILPCALPPRVEPKYLITWFMGNAKYLTKRMMPTSTTKYIDRAMEIDSQDAL 85

Query: 3109 EILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQN----IEGLKDG 3164
             +  T   D+GTYSC+    +G +  +   + +   KG  P  T+ +Q     ++ +K  
Sbjct: 86   VLRKTVREDTGTYSCKVLY-YGPSMQTAAAQIMLFVKGP-PVITSSLQKQYVLVQSIKSP 143

Query: 3165 QSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            +     C       P + I   +NG+     TR K  +      L I+     D G Y C
Sbjct: 144  KDLIINCRATGYPTPQI-IWTRYNGKLSADRTR-KMPNG----TLVISKATRGDGGAYSC 197

Query: 3225 RAYNKYGEDFTRATIN 3240
               N+ G D    T++
Sbjct: 198  LVTNELGRDLKNFTVS 213



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 10/82 (12%)

Query: 83  FAQGGNAKFEGKLRGNPTPVVSWTRK----KAPLVECNKYSMRYNEQTGDV------SLL 132
           F  G  AK   K RGNP P V+W+ K    K  +++  +   R      D       +L 
Sbjct: 228 FNVGETAKLFCKSRGNPPPAVTWSWKDIDNKTVILKDGEDDSRRRVAITDTDDFVVSTLT 287

Query: 133 IKQIGPGDEGEYTCTARNQYGE 154
           I  +   D   Y C A+N++G+
Sbjct: 288 IDSVTADDWKTYRCIAKNKFGD 309



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 9/84 (10%)

Query: 1581 TTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNN-KPLKSGSRFTETNNFGFVALDI 1639
            ++ L+NV +KEG+ A     L P  +    + W+  N K L      T T  +   A++I
Sbjct: 20   SSELQNVTVKEGEDAILPCALPPRVEPKYLITWFMGNAKYLTKRMMPTSTTKYIDRAMEI 79

Query: 1640 MS--------CLPEDSGTYTCRAI 1655
             S         + ED+GTY+C+ +
Sbjct: 80   DSQDALVLRKTVREDTGTYSCKVL 103



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 11/75 (14%)

Query: 2121 LKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYV----------ALD 2170
            +KEG+ A   C + P  +P   I WF    K     R   T    Y+          AL 
Sbjct: 28   VKEGEDAILPCALPPRVEPKYLITWFMGNAKYLT-KRMMPTSTTKYIDRAMEIDSQDALV 86

Query: 2171 ILYTYAEDSGTYMCK 2185
            +  T  ED+GTY CK
Sbjct: 87   LRKTVREDTGTYSCK 101


>SB_55336| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 771

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 30/74 (40%), Positives = 37/74 (50%), Gaps = 9/74 (12%)

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           VREG P++L+  A G P P   W KDG          + TD   STL+I  A   DA  Y
Sbjct: 75  VREGNPLILSCAADGRPIPSYEWLKDG---------HVITDSSNSTLEIESASREDAGRY 125

Query: 562 QCTAQNVAGSTATR 575
           QC A N  G+  +R
Sbjct: 126 QCVASNRIGNETSR 139



 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 55/178 (30%), Positives = 77/178 (43%), Gaps = 30/178 (16%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTL 4571
            PP  TL  +   V  G  + L     G +PI  Y WLK+G          ++ +    TL
Sbjct: 63   PPVITLQPEPTVVREGNPLILSCAADG-RPIPSYEWLKDGH---------VITDSSNSTL 112

Query: 4572 LILEAYPQDSGKYECVAINSAG-EARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PL 4629
             I  A  +D+G+Y+CVA N  G E    A+  V  P T +  + +T        I++ PL
Sbjct: 113  EIESASREDAGRYQCVASNRIGNETSRYADVTVYYPPTVNLTEKRT--------IVKLPL 164

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKG-DKLIKPSKYFQMS-RTADEYTLRISEA 4685
                   G +   SC  VG P P  QWYKG D  I    +  ++  T  EY   + EA
Sbjct: 165  -------GASETLSCPAVGNPSPIYQWYKGIDHYISNGHHISVTVATEAEYVTYLCEA 215



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 9/84 (10%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP I    +  +V EG  +  SC   G+P+P+ +W K   +I  S            TL 
Sbjct: 63   PPVITLQPEPTVVREGNPLILSCAADGRPIPSYEWLKDGHVITDS---------SNSTLE 113

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVT 4705
            I  A  ED G Y+CVA N  G  T
Sbjct: 114  IESASREDAGRYQCVASNRIGNET 137



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 24/170 (14%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V EG      C   GRP P   W      ++D +    ++ +S N  L I + +  D+G 
Sbjct: 75  VREGNPLILSCAADGRPIPSYEW------LKDGH----VITDSSNSTLEIESASREDAGR 124

Query: 463 VTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
             CVA N+ G ET+    + V     V      E+ + + +  G    L+  AVG P+P 
Sbjct: 125 YQCVASNRIGNETSRYADVTVYYPPTV---NLTEKRTIVKLPLGASETLSCPAVGNPSPI 181

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             W K G+          H       + +  A  ++   Y C A+N  G+
Sbjct: 182 YQWYK-GID---------HYISNGHHISVTVATEAEYVTYLCEAENELGT 221



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 9/81 (11%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP I  +P  + ++EG          G P P   W K+G          +IT  +++TL 
Sbjct: 63  PPVITLQPEPTVVREGNPLILSCAADGRPIPSYEWLKDG---------HVITDSSNSTLE 113

Query: 325 VRNTQKSDSGHYTLLAENPNG 345
           + +  + D+G Y  +A N  G
Sbjct: 114 IESASREDAGRYQCVASNRIG 134



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 12/89 (13%)

Query: 3693 NPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGF 3752
            +PP  T++ +  + V EG P+   C  +  G P    +W  +G         H + D   
Sbjct: 62   DPPVITLQPEPTV-VREGNPLILSCAAD--GRPIPSYEWLKDG---------HVITDSSN 109

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATT 3781
              L+I+     DAG Y C A+N+ G+ T+
Sbjct: 110  STLEIESASREDAGRYQCVASNRIGNETS 138



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 15/117 (12%)

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            DEG+Y+     +A  +     L VT P      P  T     VV EG P         + 
Sbjct: 37   DEGEYQLRLRGTAKPLDSVIALFVTDPPVITLQPEPT-----VVREGNPLILSCAADGRP 91

Query: 4749 KPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
             P+ +WL++G          +I + +N+ L I +   ED G + C A+   G  ETS
Sbjct: 92   IPSYEWLKDG---------HVITDSSNSTLEIESASREDAGRYQCVASNRIGN-ETS 138



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 10/59 (16%)

Query: 944  EWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS-ANLTI 1001
            EWLKDG  +  SS  T         L I+S +  DAG Y C A N IG  T+  A++T+
Sbjct: 96   EWLKDGHVITDSSNST---------LEIESASREDAGRYQCVASNRIGNETSRYADVTV 145



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 17/50 (34%), Positives = 21/50 (42%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            PPV    P+   V EG      C   G P P   WL +G+ I + S   L
Sbjct: 63   PPVITLQPEPTVVREGNPLILSCAADGRPIPSYEWLKDGHVITDSSNSTL 112



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 11/87 (12%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAA 1903
            P  IT    PT + EG      C  +  P P+   EW      L+ GH    S++   + 
Sbjct: 63   PPVITLQPEPTVVREGNPLILSCAADGRPIPSY--EW------LKDGHVITDSSN---ST 111

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVS 1930
            L+I +   ED+G Y C A N +G   S
Sbjct: 112  LEIESASREDAGRYQCVASNRIGNETS 138



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 9/81 (11%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            PP+ T + +P  V E          DG P+P  +W +         D  + T S+ S L 
Sbjct: 63   PPVITLQPEPTVVREGNPLILSCAADGRPIPSYEWLK---------DGHVITDSSNSTLE 113

Query: 4470 IRQVFVEDSAVFAAVAENRGG 4490
            I     ED+  +  VA NR G
Sbjct: 114  IESASREDAGRYQCVASNRIG 134



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 40/138 (28%), Positives = 56/138 (40%), Gaps = 19/138 (13%)

Query: 2326 CTSAISMTV---TAKGSIISESQRP--EGLEKIRELESAEPFKRPEIPEPVTRQRPVFTQ 2380
            C+S  S  +   T+K S I    R   EG  ++R   +A+P     I   VT    +  Q
Sbjct: 11   CSSGKSSEIIQPTSKASFILNDIRDSDEGEYQLRLRGTAKPLDSV-IALFVTDPPVITLQ 69

Query: 2381 PLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISH 2440
            P   +  ++EG      C     G P    EW ++  +I DSS  T         + I  
Sbjct: 70   PEPTV--VREGNPLILSCAAD--GRPIPSYEWLKDGHVITDSSNST---------LEIES 116

Query: 2441 VRDEDEGVYMCRASNLLG 2458
               ED G Y C ASN +G
Sbjct: 117  ASREDAGRYQCVASNRIG 134



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 11/73 (15%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG  + L    + R  P+   EW K+G  +T         D    TL I S   +D+G Y
Sbjct: 77   EGNPLILSCAADGRPIPSY--EWLKDGHVIT---------DSSNSTLEIESASREDAGRY 125

Query: 2716 TCKATNLLGEAVS 2728
             C A+N +G   S
Sbjct: 126  QCVASNRIGNETS 138


>SB_55607| Best HMM Match : ig (HMM E-Value=4.6e-17)
          Length = 274

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 20/209 (9%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFP-IKNSPDFQIHTFSTKSIL 4468
            PPI T +                   G P P ++W  +  P  ++    +I    + +IL
Sbjct: 5    PPIITSRSNVHEAKVGSDVAVACVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAIL 64

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSG 4528
             I  V  ED  ++  VA N  G +K   ++V+       R  I+PP  +  +Q V  T+ 
Sbjct: 65   TIESVTKEDEGIYCCVARNSNGQSK--PHIVILSVSYHKR--ILPPHVSPFSQVVVSTTD 120

Query: 4529 QLVRLDTKVTGT--KPIDVYWLKNGKKVQPDIRNK-------------ILEEDGTYTLLI 4573
                L   V     K   V+W  N K++    R K             +L E  T TL+I
Sbjct: 121  STTTLICAVENAPQKYTTVFWTLNSKQLTDGGRYKMATTFSTEVEYKRLLLERATMTLII 180

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECV 4602
                 QDSG+Y+C  +   G    + + V
Sbjct: 181  KHVTTQDSGEYQCGVVTHIGSGHAEIQLV 209



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 26/90 (28%), Positives = 39/90 (43%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  TG P P V W           +   +VN+     L I +VT  D G+  CVARN +G
Sbjct: 27  CVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNG 86

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
           ++     +  +   + + P  V  FS + V
Sbjct: 87  QSKPHIVILSVSYHKRILPPHVSPFSQVVV 116



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 3/60 (5%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLL-IKQIGPGDEGEYTCTARNQYGEA 155
           G+P P V W+ +  PL +C   S       G  ++L I+ +   DEG Y C ARN  G++
Sbjct: 31  GSPKPTVEWSSQ--PLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQS 88



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 7/86 (8%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLP---SGTRYKSTHDFSYV 2831
            +  S  N    K G ++   C    S  PT  +EW  +++PLP   S +R K  +  S  
Sbjct: 7    IITSRSNVHEAKVGSDVAVACVATGSPKPT--VEW--SSQPLPQCRSLSRAKIVNQGSTA 62

Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSA 2857
             L I    +ED GIY C A NS G +
Sbjct: 63   ILTIESVTKEDEGIYCCVARNSNGQS 88



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS-NKHEIITTHNHTTL 323
           PP I  +    + + G+D       +G+P+P V W         S ++ +I+   +   L
Sbjct: 5   PPIITSRSNVHEAKVGSDVAVACVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAIL 64

Query: 324 RVRNTQKSDSGHYTLLAENPNG 345
            + +  K D G Y  +A N NG
Sbjct: 65  TIESVTKEDEGIYCCVARNSNG 86



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 45/195 (23%), Positives = 74/195 (37%), Gaps = 23/195 (11%)

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGD----KLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            G  +  +C   G P PTV+W        + +  +K      TA    L I     EDEG 
Sbjct: 20   GSDVAVACVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTA---ILTIESVTKEDEGI 76

Query: 4693 YKCVAYNSAGR-------VTVAAKLKVTQPDQADNLPALTPLRD-----IVVYEGQPAQF 4740
            Y CVA NS G+       ++V+   ++  P  +     +    D     I   E  P ++
Sbjct: 77   YCCVARNSNGQSKPHIVILSVSYHKRILPPHVSPFSQVVVSTTDSTTTLICAVENAPQKY 136

Query: 4741 KT---QITSK-IKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRAT 4796
             T    + SK +    ++        E    +++ E     L+I +   +D+G + C   
Sbjct: 137  TTVFWTLNSKQLTDGGRYKMATTFSTEVEYKRLLLERATMTLIIKHVTTQDSGEYQCGVV 196

Query: 4797 TAAGQVETSAKLVVK 4811
            T  G      +LV K
Sbjct: 197  THIGSGHAEIQLVTK 211



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 28/99 (28%), Positives = 37/99 (37%), Gaps = 13/99 (13%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGF-- 1234
            P  V P S     +      L C +E        V W  N + +T G R+K    F    
Sbjct: 105  PPHVSPFSQVVVSTTDSTTTLICAVENAPQKYTTVFWTLNSKQLTDGGRYKMATTFSTEV 164

Query: 1235 -----------VALDIIHATSADTGEYTVRAVNHLGSAH 1262
                       + L I H T+ D+GEY    V H+GS H
Sbjct: 165  EYKRLLLERATMTLIIKHVTTQDSGEYQCGVVTHIGSGH 203



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 1/52 (1%)

Query: 3591 VEWFHNGKPLLTG-SRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA 3641
            VEW     P     SR K +N     IL I  V + D G+Y C A N +G++
Sbjct: 37   VEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQS 88



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 1076 TVEWYFNG-KQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQ 1128
            TVEW      Q  S +R +  +      L I SV  ED G+Y  VARN+ G+++
Sbjct: 36   TVEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQSK 89



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/85 (28%), Positives = 30/85 (35%), Gaps = 3/85 (3%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPM-RHSTRIKTVSDFGFV 3207
            P   T   N+   K G      C  V    P   +EW     P  R  +R K V+     
Sbjct: 5    PPIITSRSNVHEAKVGSDVAVAC--VATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTA 62

Query: 3208 VLDIAYTQNHDSGEYVCRAYNKYGE 3232
            +L I      D G Y C A N  G+
Sbjct: 63   ILTIESVTKEDEGIYCCVARNSNGQ 87



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/83 (24%), Positives = 31/83 (37%), Gaps = 1/83 (1%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN-PELRIHTDGGASTLD 549
           P    R +    + G  V +   A G+P P + W    +P   +    +I   G  + L 
Sbjct: 6   PIITSRSNVHEAKVGSDVAVACVATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAILT 65

Query: 550 IPRAKASDAAWYQCTAQNVAGST 572
           I      D   Y C A+N  G +
Sbjct: 66  IESVTKEDEGIYCCVARNSNGQS 88



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 1/61 (1%)

Query: 1735 IPVGDPKLRVEWLRNGVP-IEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE 1793
            +  G PK  VEW    +P   + +R   ++      L ++ V  ED G Y C A N  G+
Sbjct: 28   VATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQ 87

Query: 1794 A 1794
            +
Sbjct: 88   S 88



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 1/52 (1%)

Query: 943 VEWLKDGRPVEASSRITTFFNFGYVA-LTIKSVTVHDAGHYTCRAYNAIGQA 993
           VEW     P   S       N G  A LTI+SVT  D G Y C A N+ GQ+
Sbjct: 37  VEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQS 88



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/85 (28%), Positives = 32/85 (37%), Gaps = 4/85 (4%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNE-KLIEDSSRITKTHDFGYV 2434
            P+ T    N+   + G      C  +  G P   VEW           SR    +     
Sbjct: 6    PIITSR-SNVHEAKVGSDVAVAC--VATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTA 62

Query: 2435 SMTISHVRDEDEGVYMCRASNLLGE 2459
             +TI  V  EDEG+Y C A N  G+
Sbjct: 63   ILTIESVTKEDEGIYCCVARNSNGQ 87



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 36/173 (20%), Positives = 53/173 (30%), Gaps = 14/173 (8%)

Query: 3073 IPTGDQSMVIEWFYNG-KTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQ 3131
            + TG     +EW         +  R + V      +L I      D G Y C A N  GQ
Sbjct: 28   VATGSPKPTVEWSSQPLPQCRSLSRAKIVNQGSTAILTIESVTKEDEGIYCCVARNSNGQ 87

Query: 3132 AEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQP 3191
            ++  + +  V   K   P   +    +       +    C V         + W  N + 
Sbjct: 88   SKPHIVILSVSYHKRILPPHVSPFSQVVVSTTDSTTTLICAVENAPQKYTTVFWTLNSKQ 147

Query: 3192 MRHSTRIKTVSDFGFVV-------------LDIAYTQNHDSGEYVCRAYNKYG 3231
            +    R K  + F   V             L I +    DSGEY C      G
Sbjct: 148  LTDGGRYKMATTFSTEVEYKRLLLERATMTLIIKHVTTQDSGEYQCGVVTHIG 200


>SB_37708| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1926

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 49/192 (25%), Positives = 72/192 (37%), Gaps = 26/192 (13%)

Query: 390  LAPQFVKVCQDRDVTE-GKMTRFDCRVTGRPYPEVTWF-INDRQIRDDYNHKILVNESGN 447
            + P+ +    +  +T+ G      C V G P P +TW  + D ++R           S  
Sbjct: 1689 MRPKLLSYPSNYTITQIGSRVTLTCEVRGIPTPNITWSKLGDPRLR-----------STG 1737

Query: 448  HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GE 506
                I+  T+ D G+  C A N  G       L    +   + PK +   S   + + G 
Sbjct: 1738 STFTISGFTVEDRGIYVCTASNGIGTNVTAVSL---VQYIGLRPKLLSYPSNHTITQIGN 1794

Query: 507  PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
             + L     G PTP ITW K G P++ +           ST  I      D   Y CTA 
Sbjct: 1795 RLTLTCEVQGIPTPNITWSKLGDPLLRSK---------GSTFTISGFTVEDRGIYVCTAS 1845

Query: 567  NVAGSTATRARL 578
            N  G+  T   L
Sbjct: 1846 NGIGTNVTAVSL 1857



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 9/75 (12%)

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           VREG+P++L   A G P+P  TW  DG         ++  D    T+ + RA+  DA  Y
Sbjct: 627 VREGKPLILTCVADGRPSPSYTWILDG---------QVIQDSFNGTVKVERARREDAGSY 677

Query: 562 QCTAQNVAGSTATRA 576
           +C A N  GS  +R+
Sbjct: 678 RCVANNSIGSQTSRS 692



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 39/169 (23%), Positives = 63/169 (37%), Gaps = 22/169 (13%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V EGK     C   GRP P  TW ++ + I+D +N  + V  +             D+G 
Sbjct: 627 VREGKPLILTCVADGRPSPSYTWILDGQVIQDSFNGTVKVERARR----------EDAGS 676

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
             CVA N  G    +     ++   +V      + + + +  G    L+  A G P P  
Sbjct: 677 YRCVANNSIGSQTSRSADVTVQFPPIV--NLTRKLTIVKLPLGASDTLSCPAEGNPAPYF 734

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
            W +D    + +  L          + +  A  +D   Y C A N  G+
Sbjct: 735 RWYRDATHYVRDGHL----------VSVTVATEADYVTYMCEAVNEIGA 773



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 23/189 (12%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP+I    +  +V EG+ +  +C   G+P P+  W    ++I+ S            T++
Sbjct: 615  PPKITLHPEPTVVREGKPLILTCVADGRPSPSYTWILDGQVIQDSF---------NGTVK 665

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTV-AAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
            +  A  ED G Y+CVA NS G  T  +A + V  P   +    LT ++   +  G     
Sbjct: 666  VERARREDAGSYRCVANNSIGSQTSRSADVTVQFPPIVNLTRKLTIVK---LPLGASDTL 722

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
                     P  +W R+            + +G+   + +    E D  T+ C A    G
Sbjct: 723  SCPAEGNPAPYFRWYRDAT--------HYVRDGHLVSVTVAT--EADYVTYMCEAVNEIG 772

Query: 4801 QVETSAKLV 4809
                + KLV
Sbjct: 773  ADNATFKLV 781



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 38/125 (30%), Positives = 46/125 (36%), Gaps = 17/125 (13%)

Query: 460  SGVV-TCVARNKSGETAF-----QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
            SGV+ TC +RN S           CR++      +  P  +   S   VR G  V L   
Sbjct: 1321 SGVIKTCSSRNSSSVQRVTWVFPSCRID--RYFFLGKPTLLSYPSNHTVRNGTSVRLECH 1378

Query: 514  AVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
              G PTP ITW K G P               S  +I      D   Y CTA N  G+  
Sbjct: 1379 VKGKPTPIITWTKFGSP---------QWLSSGSVANISNVTTEDRGIYVCTASNGIGTNV 1429

Query: 574  TRARL 578
            T   L
Sbjct: 1430 TAVSL 1434



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 9/81 (11%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PPKI   P  + ++EG          G P P  TW  +GQ         +I    + T++
Sbjct: 615 PPKITLHPEPTVVREGKPLILTCVADGRPSPSYTWILDGQ---------VIQDSFNGTVK 665

Query: 325 VRNTQKSDSGHYTLLAENPNG 345
           V   ++ D+G Y  +A N  G
Sbjct: 666 VERARREDAGSYRCVANNSIG 686



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 49/205 (23%), Positives = 75/205 (36%), Gaps = 36/205 (17%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP  TL  +   V  G+ + L     G       W+ +G+ +Q              T+ 
Sbjct: 615  PPKITLHPEPTVVREGKPLILTCVADGRPSPSYTWILDGQVIQDSFNG---------TVK 665

Query: 4573 ILEAYPQDSGKYECVAINSAG-EARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLK 4630
            +  A  +D+G Y CVA NS G +    A+  V  P   +  +  T        I++ PL 
Sbjct: 666  VERARREDAGSYRCVANNSIGSQTSRSADVTVQFPPIVNLTRKLT--------IVKLPL- 716

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
                  G +   SC   G P P  +WY+       + Y +     D + + ++ A   D 
Sbjct: 717  ------GASDTLSCPAEGNPAPYFRWYR-----DATHYVR-----DGHLVSVTVATEADY 760

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQP 4715
              Y C A N  G      KL    P
Sbjct: 761  VTYMCEAVNEIGADNATFKLVQVGP 785



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 37/133 (27%), Positives = 53/133 (39%), Gaps = 14/133 (10%)

Query: 3110 ILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHF 3169
            I G    D G Y C A+N  G    +V L    +  G +P+  ++  N    + G     
Sbjct: 1742 ISGFTVEDRGIYVCTASNGIGTNVTAVSLV---QYIGLRPKLLSYPSNHTITQIGNRLTL 1798

Query: 3170 ECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNK 3229
             C V  +  P+  I W   G P+  S +  T +  GF V         D G YVC A N 
Sbjct: 1799 TCEVQGIPTPN--ITWSKLGDPLLRS-KGSTFTISGFTV--------EDRGIYVCTASNG 1847

Query: 3230 YGEDFTRATINCY 3242
             G + T  ++  Y
Sbjct: 1848 IGTNVTAVSLVQY 1860



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 21/188 (11%)

Query: 4623 PEIIE-PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P+++  P    I   G  +  +C++ G P P + W    KL  P    ++  T   +T  
Sbjct: 1691 PKLLSYPSNYTITQIGSRVTLTCEVRGIPTPNITW---SKLGDP----RLRSTGSTFT-- 1741

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            IS    ED G Y C A N  G    A  L V        L +  P    +   G      
Sbjct: 1742 ISGFTVEDRGIYVCTASNGIGTNVTAVSL-VQYIGLRPKLLSY-PSNHTITQIGNRLTLT 1799

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
             ++     P I W + G          ++    +   + G T  ED G + C A+   G 
Sbjct: 1800 CEVQGIPTPNITWSKLGD--------PLLRSKGSTFTISGFTV-EDRGIYVCTASNGIGT 1850

Query: 4802 VETSAKLV 4809
              T+  LV
Sbjct: 1851 NVTAVSLV 1858



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 11/90 (12%)

Query: 3830 PKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSL 3889
            P  ++   +HTV     VR EC V+ K  P +    + + + L SG              
Sbjct: 1356 PTLLSYPSNHTVRNGTSVRLECHVKGKPTPIITWTKFGSPQWLSSGS-----------VA 1404

Query: 3890 DILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
            +I  V  ED G Y+C A N  G + T  ++
Sbjct: 1405 NISNVTTEDRGIYVCTASNGIGTNVTAVSL 1434



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 22/88 (25%), Positives = 32/88 (36%), Gaps = 9/88 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P ++    +  V  G ++   C + GKP P + W         +K+      +      I
Sbjct: 1356 PTLLSYPSNHTVRNGTSVRLECHVKGKPTPIITW---------TKFGSPQWLSSGSVANI 1406

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVAAKL 4710
            S    ED G Y C A N  G    A  L
Sbjct: 1407 SNVTTEDRGIYVCTASNGIGTNVTAVSL 1434



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 13/88 (14%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSL-DI 2835
            +S+ +N   + G ++  EC+V+    PT  I W          T++ S    S  S+ +I
Sbjct: 1359 LSYPSNHTVRNGTSVRLECHVKGK--PTPIITW----------TKFGSPQWLSSGSVANI 1406

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSL 2863
            ++   ED GIY C A+N  G+  T+ SL
Sbjct: 1407 SNVTTEDRGIYVCTASNGIGTNVTAVSL 1434



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 1341 TMRVEWFCNGKP--IKTGHRF-RPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTS 1397
            ++R+E    GKP  I T  +F  P +       ++ +V  ED G+Y C A+N +G  VT+
Sbjct: 1372 SVRLECHVKGKPTPIITWTKFGSPQWLSSGSVANISNVTTEDRGIYVCTASNGIGTNVTA 1431

Query: 1398 CAL 1400
             +L
Sbjct: 1432 VSL 1434



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 11/84 (13%)

Query: 920  SIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDA 979
            +++ G     E  ++  G  T  + W K G P   SS        G VA  I +VT  D 
Sbjct: 1366 TVRNGTSVRLECHVK--GKPTPIITWTKFGSPQWLSS--------GSVA-NISNVTTEDR 1414

Query: 980  GHYTCRAYNAIGQATTSANLTIVT 1003
            G Y C A N IG   T+ +L   T
Sbjct: 1415 GIYVCTASNGIGTNVTAVSLVQYT 1438



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 14/42 (33%), Positives = 18/42 (42%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            PP     P+   V EG+     C   G P P   W+L+G  I
Sbjct: 615  PPKITLHPEPTVVREGKPLILTCVADGRPSPSYTWILDGQVI 656



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 11/91 (12%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P   ++  +Y     G  V L  +V     PN  I W K G       RL+ST      T
Sbjct: 1691 PKLLSYPSNYTITQIGSRVTLTCEVRGIPTPN--ITWSKLG-----DPRLRSTGS----T 1739

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVSTASI 2732
             +I+    +D GIY C A+N +G  V+  S+
Sbjct: 1740 FTISGFTVEDRGIYVCTASNGIGTNVTAVSL 1770



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 15/97 (15%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G  T  + W K G P+   S+ +TF        TI   TV D G Y C A N IG   T+
Sbjct: 1804 GIPTPNITWSKLGDPL-LRSKGSTF--------TISGFTVEDRGIYVCTASNGIGTNVTA 1854

Query: 997  ANLTIVT--KKDIIAESQHPGGLEKIQYLEDASRYSK 1031
             +L   T   KD  A+ + P  +  + + E   RYSK
Sbjct: 1855 VSLVQYTGCTKD-CAKKEVPVHVISLLWTE---RYSK 1887



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 10/98 (10%)

Query: 253  STEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKH 312
            S  IDR    +  P +   P N  ++ G   + +  + G P P +TW K G     S   
Sbjct: 1344 SCRIDRYFF-LGKPTLLSYPSNHTVRNGTSVRLECHVKGKPTPIITWTKFGSPQWLS--- 1399

Query: 313  EIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
                  + +   + N    D G Y   A N  G  VT+
Sbjct: 1400 ------SGSVANISNVTTEDRGIYVCTASNGIGTNVTA 1431



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 13/111 (11%)

Query: 1443 KPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYV 1502
            KP  ++ P +   V  G  V  EC ++        + W K G P  +          G V
Sbjct: 1355 KPTLLSYPSN-HTVRNGTSVRLECHVKGKPTPI--ITWTKFGSPQWLSS--------GSV 1403

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLE 1553
            A +I ++  ED GIY C A N +GT+  +  L  + T   V   + E G++
Sbjct: 1404 A-NISNVTTEDRGIYVCTASNGIGTNVTAVSLV-QYTGCTVGCVKKEVGIQ 1452



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 39/153 (25%), Positives = 57/153 (37%), Gaps = 16/153 (10%)

Query: 4463 STKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQN 4522
            ST S   I    VED  ++   A N  GT   + +LV          G+ P   +  + +
Sbjct: 1735 STGSTFTISGFTVEDRGIYVCTASNGIGTNVTAVSLVQYI-------GLRPKLLSYPSNH 1787

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
                 G  + L  +V G    ++ W K G    P +R+K      T+T+       +D G
Sbjct: 1788 TITQIGNRLTLTCEVQGIPTPNITWSKLG---DPLLRSK----GSTFTISGFTV--EDRG 1838

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
             Y C A N  G        V     TKD  K +
Sbjct: 1839 IYVCTASNGIGTNVTAVSLVQYTGCTKDCAKKE 1871


>SB_16652| Best HMM Match : I-set (HMM E-Value=1.2e-37)
          Length = 552

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 78/331 (23%), Positives = 116/331 (35%), Gaps = 48/331 (14%)

Query: 4481 FAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGT 4540
            +A VA N  GT   S+ ++  +          PP+ T    +V V  G    L    +GT
Sbjct: 150  YACVASNTAGTGDNSSVVITVQD---------PPTITHPPSDVTVARGSAASLSCNASGT 200

Query: 4541 KPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAE 4600
             P+++ W + G              +G   L I  A  QD G Y CV  N A  A   A 
Sbjct: 201  PPLNISWSRPG---------SAFYYEGA-VLTIDSAATQDDGVYRCVVHNGAHCASRSAS 250

Query: 4601 CVVSLPATKDKPKPQTKAANAPPEIIEPL--KDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
              +++ ++  K +      NA   ++  L   + +    + I   C   GKP   + W  
Sbjct: 251  ATLNVNSSTLKHR-NLPDENAVGLVLNKLLCLNTVSTRIKGIILYCNTSGKPQANITW-S 308

Query: 4659 GDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718
            G     PS             L ++    E  G Y C A NS G    +A + V  P   
Sbjct: 309  G-----PS---GAGNLPSGNPLVLTSVIKEHAGKYLCNASNSMGWAVESAHVDVQYPPTI 360

Query: 4719 DNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVL 4778
               P     ++   Y G         +S   P I W + G           IH     VL
Sbjct: 361  VTTP-----KNTTAYLGGNVTLYCNASSHPAPQIYWAKNG-----------IHIAMGEVL 404

Query: 4779 LIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809
             +        GT+TC A+   G   T++  V
Sbjct: 405  RVA-VSSSTAGTYTCTASNGDGANATASASV 434



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 78/306 (25%), Positives = 112/306 (36%), Gaps = 52/306 (16%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP       N+ VT G  V L    TG++P++V W        P+     L    T  L 
Sbjct: 2    PPRIHGITSNLTVTEGSNVALQCNATGSEPLNVTWR------SPN--GAFLSSGVTLNLN 53

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            IL     D G Y+C A N   E     E V          KP+  +  A          +
Sbjct: 54   ILSR--NDEGSYQCSASN-GNECPVAEESVFVTVIY----KPENTSITA--------SKR 98

Query: 4633 IVAEGQAIEFSCKIVGKP-LPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            +     ++  +C    KP      +Y+GD LI        + T+  +T+ +S        
Sbjct: 99   MACVNDSVTLACASTAKPAADRYIYYRGDSLIH-------NGTSGTHTITLS---AHGTH 148

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT-PLRDIVVYEGQPAQFKTQITSKIKP 4750
            +Y CVA N+AG     + + +T  D     P +T P  D+ V  G  A      +     
Sbjct: 149  EYACVASNTAG-TGDNSSVVITVQDP----PTITHPPSDVTVARGSAASLSCNASGTPPL 203

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA--GQVETSAKL 4808
             I W R G+           +EG  AVL I +   +D G + C     A       SA L
Sbjct: 204  NISWSRPGS--------AFYYEG--AVLTIDSAATQDDGVYRCVVHNGAHCASRSASATL 253

Query: 4809 VVKSKT 4814
             V S T
Sbjct: 254  NVNSST 259



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 66/312 (21%), Positives = 104/312 (33%), Gaps = 57/312 (18%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP I   P +  +  G+ A      SG P   ++W + G              +    L 
Sbjct: 173 PPTITHPPSDVTVARGSAASLSCNASGTPPLNISWSRPGSAFY----------YEGAVLT 222

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIE 384
           + +    D G Y         C+V +G         ++   + +    +      + R  
Sbjct: 223 IDSAATQDDGVYR--------CVVHNG---------AHCASRSASATLNVNSSTLKHRNL 265

Query: 385 ISEKALAPQFVKV-CQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVN 443
             E A+     K+ C +   T  K     C  +G+P   +TW                 N
Sbjct: 266 PDENAVGLVLNKLLCLNTVSTRIKGIILYCNTSGKPQANITWS----------GPSGAGN 315

Query: 444 ESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVA-PKFVERFSTLNV 502
               + L++T+V    +G   C A N  G       ++V     +V  PK    +     
Sbjct: 316 LPSGNPLVLTSVIKEHAGKYLCNASNSMGWAVESAHVDVQYPPTIVTTPKNTTAYL---- 371

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             G  V L   A   P P+I W K+G+ I     LR+               +S A  Y 
Sbjct: 372 --GGNVTLYCNASSHPAPQIYWAKNGIHIAMGEVLRV------------AVSSSTAGTYT 417

Query: 563 CTAQNVAGSTAT 574
           CTA N  G+ AT
Sbjct: 418 CTASNGDGANAT 429



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 14/133 (10%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP I   P+N+    G +       S +P P++ W KNG   I+    E+        LR
Sbjct: 357 PPTIVTTPKNTTAYLGGNVTLYCNASSHPAPQIYWAKNG---IHIAMGEV--------LR 405

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVT-SGYLAVE-SPTESYVQDQRSQYITDTQQRETEER 382
           V     S +G YT  A N +G   T S  + VE    E  V+ +   Y+ + + +++ + 
Sbjct: 406 VA-VSSSTAGTYTCTASNGDGANATASASVTVELYEAEVSVRCKDELYVAELKNKDSPQF 464

Query: 383 IEISEKALAPQFV 395
            ++ ++ L  + V
Sbjct: 465 KDLEKRFLEQKCV 477



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 15/45 (33%), Positives = 19/45 (42%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNG 4154
            PP  V+ P   T   G      C  + HP P++ W  NG  I  G
Sbjct: 357  PPTIVTTPKNTTAYLGGNVTLYCNASSHPAPQIYWAKNGIHIAMG 401



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 16/48 (33%), Positives = 29/48 (60%)

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESA 1951
            L + +V  E +G+Y C A N++G AV S  ++VQ   +I+   ++ +A
Sbjct: 322  LVLTSVIKEHAGKYLCNASNSMGWAVESAHVDVQYPPTIVTTPKNTTA 369


>SB_5575| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 234

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 51/158 (32%), Positives = 71/158 (44%), Gaps = 15/158 (9%)

Query: 414 RVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
           RV G P P +TW  +   +R   + K  VN+S   +LMI      DSG    + +N  G+
Sbjct: 72  RVFGFPPPNITW--SGPALR---HSKSRVNQSDG-SLMIMRTEFRDSGEYQAIVKNVVGQ 125

Query: 474 TAFQCRLNVIEKEQVVAPKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
              +  L V    Q VAP  +   +T L + E    V+   + G P P I W K    + 
Sbjct: 126 AVIRTFLVV---NQGVAPLLMSFPTTPLTIVENSTAVVPCISTGFPAPVINWTKIENSMD 182

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           P+   R+  D  A T  I   + SD   Y C+A NVAG
Sbjct: 183 PS---RMSYDSRALT--IKDVRLSDVGTYVCSATNVAG 215



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 42/172 (24%), Positives = 69/172 (40%), Gaps = 14/172 (8%)

Query: 4641 EFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNS 4700
            E   ++ G P P + W  G  L    ++ +      + +L I      D G+Y+ +  N 
Sbjct: 68   ELQLRVFGFPPPNITW-SGPAL----RHSKSRVNQSDGSLMIMRTEFRDSGEYQAIVKNV 122

Query: 4701 AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGA 4759
             G+  +   L V Q   A  L +  P   + + E   A      T    P I W + E +
Sbjct: 123  VGQAVIRTFLVVNQ-GVAPLLMSF-PTTPLTIVENSTAVVPCISTGFPAPVINWTKIENS 180

Query: 4760 LIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            + P    +      ++  L I +    D GT+ C AT  AGQV  +  ++VK
Sbjct: 181  MDPSRMSY------DSRALTIKDVRLSDVGTYVCSATNVAGQVNGNVTVIVK 226



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 44/172 (25%), Positives = 73/172 (42%), Gaps = 23/172 (13%)

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
            L  +V G  P ++ W  +G  ++   ++++ + DG+  L+I+    +DSG+Y+ +  N  
Sbjct: 69   LQLRVFGFPPPNITW--SGPALRHS-KSRVNQSDGS--LMIMRTEFRDSGEYQAIVKNVV 123

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLP 4652
            G+A      VV+                AP  +  P     + E       C   G P P
Sbjct: 124  GQAVIRTFLVVNQGV-------------APLLMSFPTTPLTIVENSTAVVPCISTGFPAP 170

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
             + W K +  + PS+    SR      +R+S     D G Y C A N AG+V
Sbjct: 171  VINWTKIENSMDPSRMSYDSRALTIKDVRLS-----DVGTYVCSATNVAGQV 217



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 11/133 (8%)

Query: 447 NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNV-REG 505
           + AL+I +V  SD G   C A N+ G       + VI +   VAP+  ++   +      
Sbjct: 10  SQALIIKDVRYSDRGTYVCSATNEEGRV--NGTVTVIVQ---VAPRVHQQPKAIEFGYRP 64

Query: 506 EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTA 565
               L  R  G P P ITW     P + + + R++   G  +L I R +  D+  YQ   
Sbjct: 65  ASKELQLRVFGFPPPNITWSG---PALRHSKSRVNQSDG--SLMIMRTEFRDSGEYQAIV 119

Query: 566 QNVAGSTATRARL 578
           +NV G    R  L
Sbjct: 120 KNVVGQAVIRTFL 132



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 2/37 (5%)

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            ALTIK V + D G Y C A N  GQ   + N+T++ K
Sbjct: 192  ALTIKDVRLSDVGTYVCSATNVAGQ--VNGNVTVIVK 226



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 7/72 (9%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            I E  TA   C  I  G P   + W + E  + D SR++    +   ++TI  VR  D G
Sbjct: 152  IVENSTAVVPC--ISTGFPAPVINWTKIENSM-DPSRMS----YDSRALTIKDVRLSDVG 204

Query: 2448 VYMCRASNLLGE 2459
             Y+C A+N+ G+
Sbjct: 205  TYVCSATNVAGQ 216



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 43/217 (19%), Positives = 85/217 (39%), Gaps = 14/217 (6%)

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSV-YIQPEGXXXXXXXXXXXXXYRHVSETVEH 188
           +L+IK +   D G Y C+A N+ G    +V  I                 YR  S+ ++ 
Sbjct: 12  ALIIKDVRYSDRGTYVCSATNEEGRVNGTVTVIVQVAPRVHQQPKAIEFGYRPASKELQL 71

Query: 189 KAYGTQGYTTEQSRQTQKVAYTNGTDHSSTDDFKVDTFEYRLLREVSFRESITKRYVGES 248
           + +G        S     + ++    + S     +   E+R   E    ++I K  VG++
Sbjct: 72  RVFGFPPPNITWSGPA--LRHSKSRVNQSDGSLMIMRTEFRDSGEY---QAIVKNVVGQA 126

Query: 249 DVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLIN 308
            ++    +++    V+P  ++       + E + A      +G P P + W K     I 
Sbjct: 127 VIRTFLVVNQG---VAPLLMSFPTTPLTIVENSTAVVPCISTGFPAPVINWTK-----IE 178

Query: 309 SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           ++      +++   L +++ + SD G Y   A N  G
Sbjct: 179 NSMDPSRMSYDSRALTIKDVRLSDVGTYVCSATNVAG 215



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 13/148 (8%)

Query: 1664 SGIAIVHSKKSIYLESQHEGALPRLN-QLEDTSKYQRHSAQDEVITQAPVFTMPMKDIRV 1722
            SG A+ HSK  +   +Q +G+L  +  +  D+ +YQ  +    V+ QA + T  + +  V
Sbjct: 84   SGPALRHSKSRV---NQSDGSLMIMRTEFRDSGEYQ--AIVKNVVGQAVIRTFLVVNQGV 138

Query: 1723 AENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASN--RLTTMHD-----FGYVALNMKYV 1775
            A    +     L  V +    V  +  G P    N  ++    D     +   AL +K V
Sbjct: 139  APLLMSFPTTPLTIVENSTAVVPCISTGFPAPVINWTKIENSMDPSRMSYDSRALTIKDV 198

Query: 1776 NPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
               D GTY C A N  G+   + T+ V+
Sbjct: 199  RLSDVGTYVCSATNVAGQVNGNVTVIVK 226



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 12/129 (9%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   + +D GTY C ATN+ G+   +V +  V  +    PR     + IE      S 
Sbjct: 13   LIIKDVRYSDRGTYVCSATNEEGRVNGTVTV-IVQVA----PRVHQQPKAIEFGYRPASK 67

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
              +  V     P+  I W  +G  +RHS      SD   +++    T+  DSGEY     
Sbjct: 68   ELQLRVFGFPPPN--ITW--SGPALRHSKSRVNQSDGSLMIM---RTEFRDSGEYQAIVK 120

Query: 3228 NKYGEDFTR 3236
            N  G+   R
Sbjct: 121  NVVGQAVIR 129


>SB_30961| Best HMM Match : I-set (HMM E-Value=0)
          Length = 1018

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 48/171 (28%), Positives = 69/171 (40%), Gaps = 21/171 (12%)

Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           DV E       C  +G P P +TW  ++  I            S    L+   +    SG
Sbjct: 422 DVIENSTLIISCTASGFPEPSITWTGSNGSI-----------VSRTSLLIKKGIQREGSG 470

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
             TC A+N  G   F  RL  I      + +++    T+N  E + ++L   A G P P 
Sbjct: 471 DYTCEAQNVVG---FARRLVTINVHYPPSIEWITPHQTIN--ETDIILLYCNATGNPRPN 525

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
           ITW    V  I   ++ +   GG S   + +   SDA  Y C+A N  G T
Sbjct: 526 ITW----VKTINQGKVLLRNIGG-SVFQVGKNNRSDAGTYTCSATNYLGQT 571



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 14/127 (11%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTL 500
           V ES N   +I  VT +D G   C A N  G   A Q  + V E+ ++ A   +    ++
Sbjct: 624 VTESSNATRVIHRVTKADQGSHECAAYNIMGWGKAAQLYVRVYERPRITA---ISPDVSV 680

Query: 501 NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
            +   + V L   A G P P ITW  +G P+  N           S + +      +A  
Sbjct: 681 TINRTDSVTLKCHASGDPAPNITWSHEGAPLEHN----------GSMITLYNVTRREAGS 730

Query: 561 YQCTAQN 567
           Y+C A N
Sbjct: 731 YECKADN 737



 Score = 45.2 bits (102), Expect = 0.001
 Identities = 43/189 (22%), Positives = 74/189 (39%), Gaps = 22/189 (11%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P    +   + + E  +    C  TG P P +TW      ++     K+L+   G     
Sbjct: 495 PSIEWITPHQTINETDIILLYCNATGNPRPNITW------VKTINQGKVLLRNIGGSVFQ 548

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           +     SD+G  TC A N  G+T     +++  K    +   +   + +N    E +VL 
Sbjct: 549 VGKNNRSDAGTYTCSATNYLGQTHGNTTVDIQYKPD-DSRLSIHDIAVIN----ETLVLK 603

Query: 512 ARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
             A   P P R  ++ +G  +         T+   +T  I R   +D   ++C A N+ G
Sbjct: 604 CLADAVPQPSRYKFKVNGTTV---------TESSNATRVIHRVTKADQGSHECAAYNIMG 654

Query: 571 STATRARLY 579
                A+LY
Sbjct: 655 -WGKAAQLY 662



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 65/291 (22%), Positives = 106/291 (36%), Gaps = 55/291 (18%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            PS   + +N ++  G  + L    TG    ++ W           +N      G    L 
Sbjct: 242  PSIVTSPRNHSILEGTRLSLYCNATGFPEPEILW-----------QNSAYRTIGKGNFLT 290

Query: 4574 LEAYPQD-SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            L    +  SG Y C+A+N  G  + +A   +  P                PEII P   +
Sbjct: 291  LNKTDRVVSGTYTCLAVNLLGSYKANATVNILYP----------------PEIIHPPSRQ 334

Query: 4633 IVAEGQ--AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
             V      A+  +C  +  P+ TV  Y+G  ++  S   +   T ++ TL       +D 
Sbjct: 335  SVTVNVTGALRLNCYAMANPIATVLIYRGLNVLN-SSLGEAQYTKNDVTL-------DDG 386

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
            G+Y CVA N  G  T    + V  P     +PA      + V E          +   +P
Sbjct: 387  GEYACVAKNGHGNTTRTMVVLVRYPPLNMTVPA-----RVDVIENSTLIISCTASGFPEP 441

Query: 4751 TIQWL-REGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            +I W    G+++  T           ++L+      E +G +TC A    G
Sbjct: 442  SITWTGSNGSIVSRT-----------SLLIKKGIQREGSGDYTCEAQNVVG 481



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 54/235 (22%), Positives = 85/235 (36%), Gaps = 38/235 (16%)

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D G+Y CVA N  G        +V  P               P  +  P +  ++ E   
Sbjct: 385  DGGEYACVAKNGHGNTTRTMVVLVRYP---------------PLNMTVPARVDVI-ENST 428

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP-EDEGDYKCVAY 4698
            +  SC   G P P++ W   +  I       +SRT    +L I +    E  GDY C A 
Sbjct: 429  LIISCTASGFPEPSITWTGSNGSI-------VSRT----SLLIKKGIQREGSGDYTCEAQ 477

Query: 4699 NSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
            N  G       + V  P    ++  +TP +   + E          T   +P I W++  
Sbjct: 478  NVVGFARRLVTINVHYP---PSIEWITPHQ--TINETDIILLYCNATGNPRPNITWVK-- 530

Query: 4759 ALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSK 4813
                      ++     +V  +G     D GT+TC AT   GQ   +  + ++ K
Sbjct: 531  ---TINQGKVLLRNIGGSVFQVGKNNRSDAGTYTCSATNYLGQTHGNTTVDIQYK 582



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 40/131 (30%), Positives = 54/131 (41%), Gaps = 16/131 (12%)

Query: 441 LVNESGNHALMITN-VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           ++N S   A    N VTL D G   CVA+N  G T    R  V+       P  +   + 
Sbjct: 366 VLNSSLGEAQYTKNDVTLDDGGEYACVAKNGHGNTT---RTMVVLVRY--PPLNMTVPAR 420

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
           ++V E   ++++  A G P P ITW      I+    L I          I R  + D  
Sbjct: 421 VDVIENSTLIISCTASGFPEPSITWTGSNGSIVSRTSLLIKK-------GIQREGSGD-- 471

Query: 560 WYQCTAQNVAG 570
            Y C AQNV G
Sbjct: 472 -YTCEAQNVVG 481



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 39/159 (24%), Positives = 69/159 (43%), Gaps = 18/159 (11%)

Query: 4660 DKLIKPSKY-FQMSRT----ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            D + +PS+Y F+++ T    +   T  I      D+G ++C AYN  G    AA+L V +
Sbjct: 607  DAVPQPSRYKFKVNGTTVTESSNATRVIHRVTKADQGSHECAAYNIMG-WGKAAQLYV-R 664

Query: 4715 PDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN 4774
              +   + A++P   + +        K   +    P I W  EGA +          E N
Sbjct: 665  VYERPRITAISPDVSVTINRTDSVTLKCHASGDPAPNITWSHEGAPL----------EHN 714

Query: 4775 NAVLLIGNTYEEDTGTFTCRATTAAGQ-VETSAKLVVKS 4812
             +++ + N    + G++ C+A     +  + SA L V S
Sbjct: 715  GSMITLYNVTRREAGSYECKADNGIRKPAKASAVLSVNS 753



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 21/42 (50%), Positives = 26/42 (61%), Gaps = 1/42 (2%)

Query: 1913 DSGEYTCKAINNLGQAVS-SIRLNVQSKESIIRDSQHESALE 1953
            D GEYTC A N+ G+ VS S  L VQ K SI+   ++ S LE
Sbjct: 214  DGGEYTCTANNSFGKPVSASFFLTVQYKPSIVTSPRNHSILE 255



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 4/113 (3%)

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
            I +P K   V    +I  +C + G PLP+V W +  K  + S  F   R      L +  
Sbjct: 739  IRKPAKASAVLSVNSINLTCDVEGGPLPSVTWSR--KRSQFSIIFSPVRMRS--VLEVIP 794

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQP 4737
                D GDY C+A N  G  +    L    P  A    A+T     V    QP
Sbjct: 795  KQSRDFGDYICMARNIMGWNSHTLTLTRVDPPGAPKELAVTSFHHRVTIRWQP 847



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 40/164 (24%), Positives = 57/164 (34%), Gaps = 25/164 (15%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  +GRP P +TW           +H    + S    L  T +   D G  TC A N  G
Sbjct: 179 CTASGRPKPLITW-----------SHAPKGHVSMTQWLNKTLIDRHDGGEYTCTANNSFG 227

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
           +         ++ +    P  V      ++ EG  + L   A G P P I WQ       
Sbjct: 228 KPVSASFFLTVQYK----PSIVTSPRNHSILEGTRLSLYCNATGFPEPEILWQNSA---- 279

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
                   T G  + L + +     +  Y C A N+ GS    A
Sbjct: 280 ------YRTIGKGNFLTLNKTDRVVSGTYTCLAVNLLGSYKANA 317



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 40/185 (21%), Positives = 67/185 (36%), Gaps = 24/185 (12%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP +     +        I   C   G+P P + W        P  +  M++  ++  + 
Sbjct: 157  PPVMTSSPSNTTANVSDVISLQCTASGRPKPLITWSHA-----PKGHVSMTQWLNKTLID 211

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
                   D G+Y C A NS G+   A+     Q   +     +T  R+  + EG      
Sbjct: 212  -----RHDGGEYTCTANNSFGKPVSASFFLTVQYKPS----IVTSPRNHSILEGTRLSLY 262

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
               T   +P I W        +   ++ I +GN   L +  T    +GT+TC A    G 
Sbjct: 263  CNATGFPEPEILW--------QNSAYRTIGKGN--FLTLNKTDRVVSGTYTCLAVNLLGS 312

Query: 4802 VETSA 4806
             + +A
Sbjct: 313  YKANA 317



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 5/78 (6%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP I     +  + E          +GNPRP +TW K     IN  K  ++     +  +
Sbjct: 494 PPSIEWITPHQTINETDIILLYCNATGNPRPNITWVKT----INQGK-VLLRNIGGSVFQ 548

Query: 325 VRNTQKSDSGHYTLLAEN 342
           V    +SD+G YT  A N
Sbjct: 549 VGKNNRSDAGTYTCSATN 566



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 10/95 (10%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P I   PRN  + EG         +G P P + W  +  R I           N  TL  
Sbjct: 242 PSIVTSPRNHSILEGTRLSLYCNATGFPEPEILWQNSAYRTIGKG--------NFLTL-- 291

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTE 360
             T +  SG YT LA N  G    +  + +  P E
Sbjct: 292 NKTDRVVSGTYTCLAVNLLGSYKANATVNILYPPE 326



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G+P+  + W++       +     + + G     +   N  D+GTYTC A N LG+   +
Sbjct: 520  GNPRPNITWVKT-----INQGKVLLRNIGGSVFQVGKNNRSDAGTYTCSATNYLGQTHGN 574

Query: 1798 STLFVQSKASLQLESQHESAL 1818
            +T+ +Q K      S H+ A+
Sbjct: 575  TTVDIQYKPDDSRLSIHDIAV 595



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 42/181 (23%), Positives = 66/181 (36%), Gaps = 22/181 (12%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P  V   ++  + EG      C  TG P PE+ W           N        GN  L 
Sbjct: 242 PSIVTSPRNHSILEGTRLSLYCNATGFPEPEILW----------QNSAYRTIGKGNF-LT 290

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLN 511
           +       SG  TC+A N  G       +N++   +++ P    +  T+NV     + LN
Sbjct: 291 LNKTDRVVSGTYTCLAVNLLGSYKANATVNILYPPEIIHPP-SRQSVTVNVTGA--LRLN 347

Query: 512 ARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             A+  P   +   + G+ ++ +            TLD       D   Y C A+N  G+
Sbjct: 348 CYAMANPIATVLIYR-GLNVLNSSLGEAQYTKNDVTLD-------DGGEYACVAKNGHGN 399

Query: 572 T 572
           T
Sbjct: 400 T 400



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/99 (24%), Positives = 43/99 (43%), Gaps = 11/99 (11%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            + + P  T    D+ V  N+      +    GDP   + W   G P+E +  + T+++  
Sbjct: 665  VYERPRITAISPDVSVTINRTDSVTLKCHASGDPAPNITWSHEGAPLEHNGSMITLYN-- 722

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGE-AVTSSTLFVQS 1804
                    V   ++G+Y C+A N + + A  S+ L V S
Sbjct: 723  --------VTRREAGSYECKADNGIRKPAKASAVLSVNS 753



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 1/51 (1%)

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSS-TLFVQSKASLQLESQHESALQ 1819
            LN   ++  D G YTC A N  G+ V++S  L VQ K S+    ++ S L+
Sbjct: 205  LNKTLIDRHDGGEYTCTANNSFGKPVSASFFLTVQYKPSIVTSPRNHSILE 255



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/111 (25%), Positives = 40/111 (36%), Gaps = 10/111 (9%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           V PP +   P N+          Q   SG P+P +TW            H  +T   + T
Sbjct: 155 VDPPVMTSSPSNTTANVSDVISLQCTASGRPKPLITWSH------APKGHVSMTQWLNKT 208

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITD 373
           L      + D G YT  A N  G  V++ +        S V   R+  I +
Sbjct: 209 L----IDRHDGGEYTCTANNSFGKPVSASFFLTVQYKPSIVTSPRNHSILE 255



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 16/40 (40%), Positives = 23/40 (57%)

Query: 1913 DSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952
            D+G YTC A N LGQ   +  +++Q K    R S H+ A+
Sbjct: 556  DAGTYTCSATNYLGQTHGNTTVDIQYKPDDSRLSIHDIAV 595



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 25/118 (21%), Positives = 48/118 (40%), Gaps = 11/118 (9%)

Query: 913  TPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIK 972
            T I   +S+          +    GD    + W  +G P+E +  + T +N         
Sbjct: 672  TAISPDVSVTINRTDSVTLKCHASGDPAPNITWSHEGAPLEHNGSMITLYN--------- 722

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLEDASRYS 1030
             VT  +AG Y C+A N I +   ++ +  V   ++  + +  G L  + +    S++S
Sbjct: 723  -VTRREAGSYECKADNGIRKPAKASAVLSVNSINLTCDVE-GGPLPSVTWSRKRSQFS 778



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/58 (43%), Positives = 29/58 (50%), Gaps = 11/58 (18%)

Query: 3597 GKPLLTGSRVKTINDFGFVILEIGG-VYQ------RDAGLYTCKATN----RHGEATV 3643
            G P    + VKTIN    ++  IGG V+Q       DAG YTC ATN     HG  TV
Sbjct: 520  GNPRPNITWVKTINQGKVLLRNIGGSVFQVGKNNRSDAGTYTCSATNYLGQTHGNTTV 577



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/112 (22%), Positives = 50/112 (44%), Gaps = 13/112 (11%)

Query: 1439 SVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHD 1498
            +V  KP  VT P++  +++EG  +   C      +   ++ W  +         +R I  
Sbjct: 237  TVQYKPSIVTSPRN-HSILEGTRLSLYCNATGFPEP--EILWQNSA--------YRTIGK 285

Query: 1499 FGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEA 1550
              ++ L+  D +   SG YTC AVNL+G+ + +  +      +I+     ++
Sbjct: 286  GNFLTLNKTDRVV--SGTYTCLAVNLLGSYKANATVNILYPPEIIHPPSRQS 335



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 14/46 (30%), Positives = 24/46 (52%)

Query: 4108 RCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN 4153
            R PP+ +++P  V V E       C  +G P+P + W  +  +IV+
Sbjct: 409  RYPPLNMTVPARVDVIENSTLIISCTASGFPEPSITWTGSNGSIVS 454



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 9/76 (11%)

Query: 2660 VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKA 2719
            +Y  A   PR  PN  I W K   T+  G  L    + G     +      D+G YTC A
Sbjct: 514  LYCNATGNPR--PN--ITWVK---TINQGKVLLR--NIGGSVFQVGKNNRSDAGTYTCSA 564

Query: 2720 TNLLGEAVSTASIKIE 2735
            TN LG+     ++ I+
Sbjct: 565  TNYLGQTHGNTTVDIQ 580


>SB_10041| Best HMM Match : ig (HMM E-Value=3.5e-06)
          Length = 333

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 38/154 (24%), Positives = 60/154 (38%), Gaps = 11/154 (7%)

Query: 375 QQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRD 434
           Q   +E+ I ++ +             DV E       C  +GRP P VTW +N      
Sbjct: 184 QALPSEKAIPVTSRQRKRLNNNTATSHDVAEHDDFNVTCSASGRPAPNVTW-VNKT---- 238

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
             +   + + +G+  L +  +    +GV  C A N  G+ A    + +     V  P  +
Sbjct: 239 --SGSPVAHGTGSATLSLLKIQRHQAGVYQCQATNDVGKGAITQDVTI----NVQYPPEI 292

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
                  VR GE + L     G PTP ++W K G
Sbjct: 293 TPMHNTTVRAGETITLTCTVAGNPTPSVSWSKAG 326



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 15/92 (16%)

Query: 4567 GTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEII 4626
            G+ TL +L+     +G Y+C A N  G+     +  +++                PPEI 
Sbjct: 248  GSATLSLLKIQRHQAGVYQCQATNDVGKGAITQDVTINV--------------QYPPEIT 293

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
             P+ +  V  G+ I  +C + G P P+V W K
Sbjct: 294  -PMHNTTVRAGETITLTCTVAGNPTPSVSWSK 324



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 28/128 (21%), Positives = 49/128 (38%), Gaps = 14/128 (10%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            VAE      +C   G+P P V W      +  +    ++      TL + +      G Y
Sbjct: 212  VAEHDDFNVTCSASGRPAPNVTW------VNKTSGSPVAHGTGSATLSLLKIQRHQAGVY 265

Query: 4694 KCVAYNSAGR--VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPT 4751
            +C A N  G+  +T    + V  P      P +TP+ +  V  G+       +     P+
Sbjct: 266  QCQATNDVGKGAITQDVTINVQYP------PEITPMHNTTVRAGETITLTCTVAGNPTPS 319

Query: 4752 IQWLREGA 4759
            + W + G+
Sbjct: 320  VSWSKAGS 327



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 13/37 (35%), Positives = 22/37 (59%)

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  TLS+  ++   +G+Y C+ATN +G+   T  + I
Sbjct: 248  GSATLSLLKIQRHQAGVYQCQATNDVGKGAITQDVTI 284


>SB_46550| Best HMM Match : Asn_synthase (HMM E-Value=0)
          Length = 1663

 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 1/87 (1%)

Query: 4627 EPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEA 4685
            EPL+D  V   +  E +CKI     P  V W   D  +  +  +++SRT D +TL++   
Sbjct: 880  EPLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPL 939

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
               D G Y C+A + AG     AK+ V
Sbjct: 940  AVADTGYYTCIASSPAGSARSTAKVTV 966



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYP-EVTWFINDRQIRDDYNHKILVNESGN-HALM 451
           F +  QD  V   + T   C+++   +P +V+W  ND  + D  N K  ++ +G+ H L 
Sbjct: 878 FTEPLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCD--NDKYRISRTGDTHTLK 935

Query: 452 ITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
           +  + ++D+G  TC+A + +G      ++ V+
Sbjct: 936 LGPLAVADTGYYTCIASSPAGSARSTAKVTVL 967



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 2/100 (2%)

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            +FT   Q++ V + +   L  K++    P  V W  N   +  + + +I     T+TL +
Sbjct: 877  TFTEPLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKL 936

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAE-CVVSLPATKDKP 4612
                  D+G Y C+A + AG AR  A+  V+ +P    KP
Sbjct: 937  GPLAVADTGYYTCIASSPAGSARSTAKVTVLGVPEPPYKP 976



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 3422 FTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILE 3481
            FT PL +I  +   E      +++  D P  KV W WN   L    ++R         L+
Sbjct: 878  FTEPLQDIA-VNNTEYTELTCKISSPDFP-YKVSWAWNDTPLCDNDKYRISRTGDTHTLK 935

Query: 3482 ISPTYPEDSGEYLCRAYNNYGEAVTTASMKVQG 3514
            + P    D+G Y C A +  G A +TA + V G
Sbjct: 936  LGPLAVADTGYYTCIASSPAGSARSTAKVTVLG 968



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKP-TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTY 4784
            PL+DI V   +  +   +I+S   P  + W      + +   +++   G+   L +G   
Sbjct: 881  PLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLA 940

Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVV 4810
              DTG +TC A++ AG   ++AK+ V
Sbjct: 941  VADTGYYTCIASSPAGSARSTAKVTV 966



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 1/92 (1%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDI 2835
            F   L +I     +     C +  S D   K+ W +N+ PL    +Y+ +      +L +
Sbjct: 878  FTEPLQDIAVNNTEYTELTCKIS-SPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKL 936

Query: 2836 THTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
                  D+G YTC A++  GSA ++  +   G
Sbjct: 937  GPLAVADTGYYTCIASSPAGSARSTAKVTVLG 968



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 1/87 (1%)

Query: 493 FVERFSTLNVREGEPVVLNARAVGTPTP-RITWQKDGVPIIPNPELRIHTDGGASTLDIP 551
           F E    + V   E   L  +      P +++W  +  P+  N + RI   G   TL + 
Sbjct: 878 FTEPLQDIAVNNTEYTELTCKISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKLG 937

Query: 552 RAKASDAAWYQCTAQNVAGSTATRARL 578
               +D  +Y C A + AGS  + A++
Sbjct: 938 PLAVADTGYYTCIASSPAGSARSTAKV 964



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 22/74 (29%), Positives = 41/74 (55%), Gaps = 4/74 (5%)

Query: 296 RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           +V+W  N   L +++K+ I  T +  TL++     +D+G+YT +A +P G   ++  + V
Sbjct: 907 KVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLAVADTGYYTCIASSPAGSARSTAKVTV 966

Query: 356 ----ESPTESYVQD 365
               E P + YV+D
Sbjct: 967 LGVPEPPYKPYVKD 980



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 1/92 (1%)

Query: 3560 FTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEI 3619
            FT    D+ ++        C+ I   D   +V W  N  PL    + +         L++
Sbjct: 878  FTEPLQDIAVNNTEYTELTCK-ISSPDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKL 936

Query: 3620 GGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            G +   D G YTC A++  G A  + K+ V G
Sbjct: 937  GPLAVADTGYYTCIASSPAGSARSTAKVTVLG 968



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 1298 TKQVREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGH 1357
            TK   E +    +  F+  L +I         L C++    D   +V W  N  P+    
Sbjct: 863  TKNFEEPLEDDGSITFTEPLQDIAVNNTEYTELTCKISSP-DFPYKVSWAWNDTPLCDND 921

Query: 1358 RFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            ++R +   D   L L  +   D+G YTC A++  G A ++  + V+
Sbjct: 922  KYRISRTGDTHTLKLGPLAVADTGYYTCIASSPAGSARSTAKVTVL 967



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 2/90 (2%)

Query: 3697 FTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALD 3756
            FT  ++D I V         C++     P  ++ W  N  P     +           L 
Sbjct: 878  FTEPLQD-IAVNNTEYTELTCKISSPDFP-YKVSWAWNDTPLCDNDKYRISRTGDTHTLK 935

Query: 3757 IDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            +  +   D G YTC A++  GSA +TAK+T
Sbjct: 936  LGPLAVADTGYYTCIASSPAGSARSTAKVT 965



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 1/71 (1%)

Query: 1866 CRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL 1925
            C+I   PD   +V W +N   L    +YR S       L +  +   D+G YTC A +  
Sbjct: 897  CKISS-PDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLAVADTGYYTCIASSPA 955

Query: 1926 GQAVSSIRLNV 1936
            G A S+ ++ V
Sbjct: 956  GSARSTAKVTV 966



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/106 (21%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 1964 YKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQG 2023
            ++  ++DD  +     F +P+++  V       L   ++  + P  +V W  N  P+   
Sbjct: 866  FEEPLEDDGSIT----FTEPLQDIAVNNTEYTELTCKISSPDFP-YKVSWAWNDTPLCDN 920

Query: 2024 HRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
             +++ +       L +      DTG Y C A++  G A +T+ V V
Sbjct: 921  DKYRISRTGDTHTLKLGPLAVADTGYYTCIASSPAGSARSTAKVTV 966



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 18/60 (30%), Positives = 28/60 (46%)

Query: 2675 KIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            K+ W  N   L    + + +      TL +  L   D+G YTC A++  G A STA + +
Sbjct: 907  KVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLAVADTGYYTCIASSPAGSARSTAKVTV 966



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 4/54 (7%)

Query: 103 VSWTRKKAPLVECNKYSMRYNEQTGDV-SLLIKQIGPGDEGEYTCTARNQYGEA 155
           VSW     PL + +KY +    +TGD  +L +  +   D G YTC A +  G A
Sbjct: 908 VSWAWNDTPLCDNDKYRI---SRTGDTHTLKLGPLAVADTGYYTCIASSPAGSA 958



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 911  FKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALT 970
            F  P++D I++    +     ++    D   +V W  +  P+  + +           L 
Sbjct: 878  FTEPLQD-IAVNNTEYTELTCKISS-PDFPYKVSWAWNDTPLCDNDKYRISRTGDTHTLK 935

Query: 971  IKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            +  + V D G+YTC A +  G A ++A +T++
Sbjct: 936  LGPLAVADTGYYTCIASSPAGSARSTAKVTVL 967



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 1/81 (1%)

Query: 3989 ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLC 4048
            E T+  C+++    P  KV W +N  PL   +++          +  G +   D+G Y C
Sbjct: 891  EYTELTCKISSPDFP-YKVSWAWNDTPLCDNDKYRISRTGDTHTLKLGPLAVADTGYYTC 949

Query: 4049 RATNLYGMDETKAVIKTTGKP 4069
             A++  G   + A +   G P
Sbjct: 950  IASSPAGSARSTAKVTVLGVP 970


>SB_9202| Best HMM Match : ig (HMM E-Value=5e-40)
          Length = 1604

 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 53/199 (26%), Positives = 87/199 (43%), Gaps = 19/199 (9%)

Query: 4623 PEIIEPLKDKIVAEGQA-IEFSCKIVGKP-LPTVQWYKGDKL-IKP-----SKYFQMSRT 4674
            P +IE   ++ VA+  + +EF CK  G+P + +  W+KG    + P     SKYF    +
Sbjct: 333  PVVIELTANQSVAKSASFVEFFCKAEGEPAVSSYSWFKGQTTAVSPIANDNSKYFISDGS 392

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYE 4734
              E  LR++    +D G Y C A NS G + + +   +T    A  +  +T +  + V E
Sbjct: 393  NGEKRLRVNTLLKDDAGWYTCAARNSRG-LGLGSSTYLTVL-YAPEVMDITFIPSVTVDE 450

Query: 4735 GQPAQFKTQITSKIKPTIQW--LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFT 4792
                  +        P   W    E  +I  + D      G +  L++    ++D G +T
Sbjct: 451  YDDVTLRCISDGGPIPFFTWRFKNENKVIQGSGD-----RGRD--LVVSRAKKDDAGNYT 503

Query: 4793 CRATTAAGQVETSAKLVVK 4811
            C AT + G  + S  L VK
Sbjct: 504  CVATNSQGVNQHSELLYVK 522



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 51/197 (25%), Positives = 79/197 (40%), Gaps = 18/197 (9%)

Query: 392 PQFVKVCQDRDVTEG-KMTRFDCRVTGRP-YPEVTWFINDRQ----IRDDYNHKILVNE- 444
           P  +++  ++ V +      F C+  G P     +WF         I +D N K  +++ 
Sbjct: 333 PVVIELTANQSVAKSASFVEFFCKAEGEPAVSSYSWFKGQTTAVSPIAND-NSKYFISDG 391

Query: 445 -SGNHALMITNVTLSDSGVVTCVARNKSG-ETAFQCRLNVIEKEQVVAPKFVERFSTLNV 502
            +G   L +  +   D+G  TC ARN  G        L V+   +V+   F+    ++ V
Sbjct: 392 SNGEKRLRVNTLLKDDAGWYTCAARNSRGLGLGSSTYLTVLYAPEVMDITFI---PSVTV 448

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
            E + V L   + G P P  TW+        N  ++   D G   L + RAK  DA  Y 
Sbjct: 449 DEYDDVTLRCISDGGPIPFFTWRFKN----ENKVIQGSGDRGRD-LVVSRAKKDDAGNYT 503

Query: 563 CTAQNVAGSTATRARLY 579
           C A N  G       LY
Sbjct: 504 CVATNSQGVNQHSELLY 520



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 43/165 (26%), Positives = 70/165 (42%), Gaps = 17/165 (10%)

Query: 381 ERIEISEKALAPQFVKVCQDRD--VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNH 438
           +RI I+ + + P FV      D   TE + + + C   G+P P++ WF+N R +  D   
Sbjct: 605 KRIRITVQ-VGPAFVTSLPPNDGIKTENETSNYTCTADGKPAPDILWFVNGRNVTVDSPE 663

Query: 439 KILVNESG-----NHALM----ITNVTLS--DSGVVTCVARNKSGETAFQCRLNVIEKEQ 487
              V   G     N  L+    + +V  S    G ++CVARN +G       L V  +  
Sbjct: 664 LGRVTAQGSVSPANVKLIRVESVLHVMYSWLHDGNISCVARNPAGSVQQTTLLQV--RYC 721

Query: 488 VVAPKFVERFSTLNVREGEPVVLNARAVGTP-TPRITWQKDGVPI 531
            V   + +    + + EG     + R +G P T  + W  + V I
Sbjct: 722 PVVKTYADHPKNVTLDEGGDATFSCRTIGNPVTDYVEWYFNEVKI 766



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 43/186 (23%), Positives = 76/186 (40%), Gaps = 27/186 (14%)

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPT-VQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            K+  + EG    FSC+ +G P+   V+WY  +  I  S+        + +T R       
Sbjct: 732  KNVTLDEGGDATFSCRTIGNPVTDYVEWYFNEVKIPDSR-------GNSFTRR--NVGGR 782

Query: 4689 DEGDYKCVAYNS---AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQIT 4745
            D G Y C  +++    G     A L +    +    P +T        E   A    ++T
Sbjct: 783  DAGLYSCRGFSTLCDRGGPLFGAHLFIKTGPRITFYPKVTRAN-----ETGSALLYCRVT 837

Query: 4746 SKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
               +P + W +EG       +  ++H G     L+GN   +D+G + C+A  +      +
Sbjct: 838  GVPEPVVTWYKEG-------NATLLHTGKE--FLVGNLTYQDSGNYICQAVNSEATDRAT 888

Query: 4806 AKLVVK 4811
             +LVV+
Sbjct: 889  LELVVQ 894



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 18/162 (11%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           CRVTG P P VTW+        + N  +L   +G    ++ N+T  DSG   C A N   
Sbjct: 834 CRVTGVPEPVVTWY-------KEGNATLL--HTGKE-FLVGNLTYQDSGNYICQAVN--S 881

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQK--DGVP 530
           E   +  L ++ +   V        + +    G+   +   A   P     W +  D +P
Sbjct: 882 EATDRATLELVVQVVPVITTDKPTDTDIAGEAGKVSSIRCSARSEPPAEYWWTRGSDRIP 941

Query: 531 II-PNPELR-IHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           +   +P +R I+ +G + TL I  A   +   Y C A+N+ G
Sbjct: 942 LTGSSPRVRSINDEGNSRTLMIEVASFGET--YYCHARNIMG 981



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 24/183 (13%)

Query: 4637 GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCV 4696
            G A+ + C++ G P P V WYK            +  T  E+   +     +D G+Y C 
Sbjct: 828  GSALLY-CRVTGVPEPVVTWYKEGNA-------TLLHTGKEFL--VGNLTYQDSGNYICQ 877

Query: 4697 AYNS--AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
            A NS    R T+   ++V  P    + P  T   DI    G+ +  +    S+      W
Sbjct: 878  AVNSEATDRATLELVVQVV-PVITTDKPTDT---DIAGEAGKVSSIRCSARSEPPAEYWW 933

Query: 4755 LREGALIPET---PDFQMIH-EGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             R    IP T   P  + I+ EGN+  L+I         T+ C A    G+     K V+
Sbjct: 934  TRGSDRIPLTGSSPRVRSINDEGNSRTLMI--EVASFGETYYCHARNIMGR--DIQKYVI 989

Query: 4811 KSK 4813
            + K
Sbjct: 990  REK 992



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 5/127 (3%)

Query: 3804 SGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHT-VEESEGVRFECRVEPKEDPKLR 3862
            SG  I +      +D    E +V   P   T   + T +    G     R   + +P   
Sbjct: 871  SGNYICQAVNSEATDRATLELVVQVVPVITTDKPTDTDIAGEAGKVSSIRCSARSEPPAE 930

Query: 3863 IEWYRNGKLLP---SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
              W R    +P   S  R R++ D G  S  ++   A     Y C A N  G D  K  I
Sbjct: 931  YWWTRGSDRIPLTGSSPRVRSINDEGN-SRTLMIEVASFGETYYCHARNIMGRDIQKYVI 989

Query: 3920 SCKKLPD 3926
              K  PD
Sbjct: 990  REKGPPD 996



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 14/72 (19%)

Query: 3564 PSDLILSENSSAHFECRLI--PVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGG 3621
            P ++ L E   A F CR I  PV D    VEW+ N +  +  SR  +     F    +GG
Sbjct: 731  PKNVTLDEGGDATFSCRTIGNPVTDY---VEWYFN-EVKIPDSRGNS-----FTRRNVGG 781

Query: 3622 VYQRDAGLYTCK 3633
               RDAGLY+C+
Sbjct: 782  ---RDAGLYSCR 790



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 16/108 (14%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK--VLQSGHRYRTSN 1897
            +   PR IT     T+ +E  SA   CR+   P+P   V WY  G   +L +G  +   N
Sbjct: 809  IKTGPR-ITFYPKVTRANETGSALLYCRVTGVPEPV--VTWYKEGNATLLHTGKEFLVGN 865

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRD 1945
                     LT   +DSG Y C+A+N+     +++ L VQ    I  D
Sbjct: 866  ---------LTY--QDSGNYICQAVNSEATDRATLELVVQVVPVITTD 902



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 9/77 (11%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P+I   P+ ++  E   A    +++G P P VTW+K G   +          H      V
Sbjct: 813 PRITFYPKVTRANETGSALLYCRVTGVPEPVVTWYKEGNATL---------LHTGKEFLV 863

Query: 326 RNTQKSDSGHYTLLAEN 342
            N    DSG+Y   A N
Sbjct: 864 GNLTYQDSGNYICQAVN 880



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 35/157 (22%), Positives = 58/157 (36%), Gaps = 9/157 (5%)

Query: 1067 VEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGE 1126
            V  Q   + T +W F+     S ++ Q      YVA +IA+   E+  V    A N  G 
Sbjct: 228  VYAQEGTSYTFDWRFSSTSTRSFSQWQVTKPPNYVATNIATKTGENGPVQVASAYN--GR 285

Query: 1127 AQLSASMTVETRSSIDTSSIHRGLYEKTRHIEESKFVEPMYQIEEISKSKPVFVQPLSNP 1186
                +   V  R      +   G Y    H  +  F+     +  +   KPV ++  +N 
Sbjct: 286  VTFESGNQVGFRLD-SLQAADNGRYMCNLHFADGGFLTDTANL--VVVDKPVVIELTANQ 342

Query: 1187 PPVSEGKNIHLECRLEPMGDPTM-RVEWFHNGRSVTV 1222
                    +   C+ E  G+P +    WF  G++  V
Sbjct: 343  SVAKSASFVEFFCKAE--GEPAVSSYSWF-KGQTTAV 376



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 19/128 (14%)

Query: 405 EGKMTRFDCRVTGRPYPE-VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVV 463
           EG    F CR  G P  + V W+ N+ +I D          S  ++    NV   D+G+ 
Sbjct: 738 EGGDATFSCRTIGNPVTDYVEWYFNEVKIPD----------SRGNSFTRRNVGGRDAGLY 787

Query: 464 TCVARNK---SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
           +C   +     G   F   L +    ++    F  + +  N  E    +L  R  G P P
Sbjct: 788 SCRGFSTLCDRGGPLFGAHLFIKTGPRIT---FYPKVTRAN--ETGSALLYCRVTGVPEP 842

Query: 521 RITWQKDG 528
            +TW K+G
Sbjct: 843 VVTWYKEG 850



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 11/88 (12%)

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
            +VTG     V W K G         + L  + TY         QDSG Y C A+NS    
Sbjct: 835  RVTGVPEPVVTWYKEGNATLLHTGKEFLVGNLTY---------QDSGNYICQAVNSEATD 885

Query: 4596 RCDAECVVS-LPA-TKDKPKPQTKAANA 4621
            R   E VV  +P  T DKP     A  A
Sbjct: 886  RATLELVVQVVPVITTDKPTDTDIAGEA 913



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 2/43 (4%)

Query: 4111 PVFV-SLPDAVTVE-EGEWARFCCRVTGHPKPRVMWLLNGNTI 4151
            P FV SLP    ++ E E + + C   G P P ++W +NG  +
Sbjct: 615  PAFVTSLPPNDGIKTENETSNYTCTADGKPAPDILWFVNGRNV 657



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 12/71 (16%)

Query: 2388 IQEGQTAHFDCRLIPVGDP-TLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
            + EG  A F CR I  G+P T  VEW+ NE  I DS            S T  +V   D 
Sbjct: 736  LDEGGDATFSCRTI--GNPVTDYVEWYFNEVKIPDSRGN---------SFTRRNVGGRDA 784

Query: 2447 GVYMCRASNLL 2457
            G+Y CR  + L
Sbjct: 785  GLYSCRGFSTL 795



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 9/102 (8%)

Query: 263 VSPPKIAQKPRNSKLQEGAD-AQFQVQLSGNPR-PRVTWFKNGQRLI----NSNKHEIIT 316
           V  P + +   N  + + A   +F  +  G P     +WFK     +    N N    I+
Sbjct: 330 VDKPVVIELTANQSVAKSASFVEFFCKAEGEPAVSSYSWFKGQTTAVSPIANDNSKYFIS 389

Query: 317 --THNHTTLRVRNTQKSDSGHYTLLAENPNGC-IVTSGYLAV 355
             ++    LRV    K D+G YT  A N  G  + +S YL V
Sbjct: 390 DGSNGEKRLRVNTLLKDDAGWYTCAARNSRGLGLGSSTYLTV 431



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 14/91 (15%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            PR T + +     + G SA   C V  V +P   + WY  G    ++T + T  +F  +V
Sbjct: 813  PRITFYPKVTRANETG-SALLYCRVTGVPEP--VVTWYKEG----NATLLHTGKEF--LV 863

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYGEDFTRATI 3239
             ++ Y    DSG Y+C+A N    D  RAT+
Sbjct: 864  GNLTY---QDSGNYICQAVNSEATD--RATL 889


>SB_45516| Best HMM Match : I-set (HMM E-Value=1.1e-26)
          Length = 939

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)

Query: 392 PQFVKVCQDRDVTEG-KMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           PQ ++  +D +V EG + T   C+  G P P++TW    +  R D   +IL   S     
Sbjct: 329 PQIIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWL---KLSRPD---QIL---SKGETF 379

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQ-CRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            IT+VT  D G+  C+ARN  G  A +   +NV  +   VAP+  E     N  EGE
Sbjct: 380 FITSVTREDHGLYRCMARNNVGAAAIKDFTINVRYRFHDVAPQIGETQLFNNADEGE 436



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 72/280 (25%), Positives = 99/280 (35%), Gaps = 36/280 (12%)

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            V    G++ +L  K TG     V W K+GK+V    R K  E      +        D  
Sbjct: 156  VQYKEGEVKKLVCKATGKPNPWVIWYKDGKEVMK--RKKRAE------IAFDPVTDADMA 207

Query: 4583 KYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF 4642
             Y+CVA NS G+        V       KPK  T   +A            V+ G  + F
Sbjct: 208  SYKCVAQNSGGKEERVTNVTVMF-----KPKETTLRTDA--------NGNTVSVGSTVSF 254

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
             C   G P PT ++Y   +   P +          +   +        G Y C+  NS G
Sbjct: 255  FCAARGYPKPTYKFYIKARGQPPRRLDYRDAELTGHIKNLGVVDSRWHGTYICIPSNSVG 314

Query: 4703 R-VTVAAKLKVTQPDQADNLPALTPLRDIVVYEG-QPAQFKTQITSKIKPTIQWLREGAL 4760
                    L V  P Q      + P RD+ V EG Q    + Q      P I WL+    
Sbjct: 315  EGPRQELLLYVRYPPQ-----IIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWLK---- 365

Query: 4761 IPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
                PD Q++ +G      I +   ED G + C A    G
Sbjct: 366  -LSRPD-QILSKGE--TFFITSVTREDHGLYRCMARNNVG 401



 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 16/123 (13%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERF--STLNVREGEP 507
           L ITNV LSD G   C  R        + ++N+I    V+AP  ++    +T+  +EGE 
Sbjct: 110 LEITNVQLSDEGNYVCELRTLF--MMIKAKINLI----VIAPAKIKSSPPATVQYKEGEV 163

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
             L  +A G P P + W KDG  ++   +         + +       +D A Y+C AQN
Sbjct: 164 KKLVCKATGKPNPWVIWYKDGKEVMKRKK--------RAEIAFDPVTDADMASYKCVAQN 215

Query: 568 VAG 570
             G
Sbjct: 216 SGG 218



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 67/287 (23%), Positives = 106/287 (36%), Gaps = 45/287 (15%)

Query: 4424 EHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            E E  +   +  G+P P + WY++   +             ++ +    V   D A +  
Sbjct: 160  EGEVKKLVCKATGKPNPWVIWYKDGKEVMKR--------KKRAEIAFDPVTDADMASYKC 211

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTG-TKP 4542
            VA+N GG  +   N+ V  K ++        +    A    V+ G  V       G  KP
Sbjct: 212  VAQNSGGKEERVTNVTVMFKPKE-------TTLRTDANGNTVSVGSTVSFFCAARGYPKP 264

Query: 4543 IDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD-SGKYECVAINSAGEARCDAEC 4601
               +++K   + QP  R    + + T  +  L        G Y C+  NS GE       
Sbjct: 265  TYKFYIK--ARGQPPRRLDYRDAELTGHIKNLGVVDSRWHGTYICIPSNSVGEG------ 316

Query: 4602 VVSLPATKDKPKPQTKA-ANAPPEIIEPLKDKIVAEG-QAIEFSCKIVGKPLPTVQWYKG 4659
                      P+ +       PP+II P +D  V EG Q     C+  G P P + W K 
Sbjct: 317  ----------PRQELLLYVRYPPQIIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWLK- 365

Query: 4660 DKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTV 4706
              L +P +      T       I+    ED G Y+C+A N+ G   +
Sbjct: 366  --LSRPDQILSKGET-----FFITSVTREDHGLYRCMARNNVGAAAI 405



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 60/251 (23%), Positives = 91/251 (36%), Gaps = 28/251 (11%)

Query: 4552 KKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDK 4611
            K V P    +I  +D   TL I      D G Y C         +     +V  PA    
Sbjct: 92   KSVPPSFLGRIRIKDRA-TLEITNVQLSDEGNYVCELRTLFMMIKAKINLIVIAPA---- 146

Query: 4612 PKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQM 4671
                 K  ++PP  ++        EG+  +  CK  GKP P V WYK  K +   K    
Sbjct: 147  -----KIKSSPPATVQ------YKEGEVKKLVCKATGKPNPWVIWYKDGKEVMKRK---- 191

Query: 4672 SRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
             + A+     +++A   D   YKCVA NS G+      + V    +   L   T      
Sbjct: 192  -KRAEIAFDPVTDA---DMASYKCVAQNSGGKEERVTNVTVMFKPKETTL--RTDANGNT 245

Query: 4732 VYEGQPAQFKTQITSKIKPTIQ-WLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
            V  G    F        KPT + +++     P   D++   E    +  +G       GT
Sbjct: 246  VSVGSTVSFFCAARGYPKPTYKFYIKARGQPPRRLDYRDA-ELTGHIKNLGVVDSRWHGT 304

Query: 4791 FTCRATTAAGQ 4801
            + C  + + G+
Sbjct: 305  YICIPSNSVGE 315



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 49/180 (27%), Positives = 73/180 (40%), Gaps = 26/180 (14%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDR---QIRDDYNHKILVNESGNHALMITNVTLSD 459
           V+ G    F C   G P P   ++I  R     R DY    L          I N+ + D
Sbjct: 246 VSVGSTVSFFCAARGYPKPTYKFYIKARGQPPRRLDYRDAELTGH-------IKNLGVVD 298

Query: 460 S---GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP-VVLNARAV 515
           S   G   C+  N  GE   Q  L  +       P+ +     +NV EG+   ++  +A 
Sbjct: 299 SRWHGTYICIPSNSVGEGPRQELLLYVR----YPPQIIRPPRDMNVDEGDQKTIVQCQAD 354

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
           G P+P+ITW K     +  P+ +I + G   T  I      D   Y+C A+N  G+ A +
Sbjct: 355 GYPSPQITWLK-----LSRPD-QILSKG--ETFFITSVTREDHGLYRCMARNNVGAAAIK 406



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 43/194 (22%), Positives = 73/194 (37%), Gaps = 19/194 (9%)

Query: 382 RIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
           + +I+   +AP  +K      V   EG++ +  C+ TG+P P V W+ + +++       
Sbjct: 135 KAKINLIVIAPAKIKSSPPATVQYKEGEVKKLVCKATGKPNPWVIWYKDGKEV------- 187

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
             +       +    VT +D     CVA+N  G+      + V+ K +    +     +T
Sbjct: 188 --MKRKKRAEIAFDPVTDADMASYKCVAQNSGGKEERVTNVTVMFKPKETTLRTDANGNT 245

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
           ++V  G  V     A G P P     K  +     P  R+       T  I      D+ 
Sbjct: 246 VSV--GSTVSFFCAARGYPKPT---YKFYIKARGQPPRRLDYRDAELTGHIKNLGVVDSR 300

Query: 560 W---YQCTAQNVAG 570
           W   Y C   N  G
Sbjct: 301 WHGTYICIPSNSVG 314



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 1/56 (1%)

Query: 4115 SLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIV-NGSRYKLTYDGMYHFDI 4169
            S P  V  +EGE  +  C+ TG P P V+W  +G  ++    R ++ +D +   D+
Sbjct: 151  SPPATVQYKEGEVKKLVCKATGKPNPWVIWYKDGKEVMKRKKRAEIAFDPVTDADM 206



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 9/82 (10%)

Query: 265 PPKIAQKPRNSKLQEGADAQF-QVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           PP+I + PR+  + EG      Q Q  G P P++TW K       S   +I++     T 
Sbjct: 328 PPQIIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWLK------LSRPDQILS--KGETF 379

Query: 324 RVRNTQKSDSGHYTLLAENPNG 345
            + +  + D G Y  +A N  G
Sbjct: 380 FITSVTREDHGLYRCMARNNVG 401



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 13/112 (11%)

Query: 4046 YLCRATNLYGMDETKAVIKTTGKPG--IVY-DSQLPKHMKSIEKI-REMEASWQVTPEQV 4101
            + C A   Y     K  IK  G+P   + Y D++L  H+K++  +      ++   P   
Sbjct: 254  FFCAARG-YPKPTYKFYIKARGQPPRRLDYRDAELTGHIKNLGVVDSRWHGTYICIPSNS 312

Query: 4102 VEESK-------ARCPPVFVSLPDAVTVEEGEWARFC-CRVTGHPKPRVMWL 4145
            V E          R PP  +  P  + V+EG+      C+  G+P P++ WL
Sbjct: 313  VGEGPRQELLLYVRYPPQIIRPPRDMNVDEGDQKTIVQCQADGYPSPQITWL 364



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 10/85 (11%)

Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
           P+   P +D +++ EG       + +  G  + ++ WLK  RP +  S+  TFF      
Sbjct: 329 PQIIRPPRD-MNVDEGDQKTI-VQCQADGYPSPQITWLKLSRPDQILSKGETFF------ 380

Query: 969 LTIKSVTVHDAGHYTCRAYNAIGQA 993
             I SVT  D G Y C A N +G A
Sbjct: 381 --ITSVTREDHGLYRCMARNNVGAA 403



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 14/50 (28%), Positives = 27/50 (54%), Gaps = 1/50 (2%)

Query: 263 VSPPKI-AQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNK 311
           ++P KI +  P   + +EG   +   + +G P P V W+K+G+ ++   K
Sbjct: 143 IAPAKIKSSPPATVQYKEGEVKKLVCKATGKPNPWVIWYKDGKEVMKRKK 192


>SB_43869| Best HMM Match : ig (HMM E-Value=2.7e-06)
          Length = 399

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 9/148 (6%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            I   C   GKP PTV W K  K        ++S    +Y LR+      D G Y C   N
Sbjct: 135  INLDCSADGKPRPTVVWLKNGKPFFKRDGVELSLRPYQYVLRLRGVVSSDNGQYTCNVSN 194

Query: 4700 SAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL---- 4755
            S   ++    + V + + +  L  + P  ++    G     K    S   P  +WL    
Sbjct: 195  SCDWISRTFTVHVKKREPSKPLIQIIP--NVTARNGDNVTLKCNAMSDSMPRFRWLILTS 252

Query: 4756 --REGALIPETPD-FQMIHEGNNAVLLI 4780
                  LI ETP+ +++I +  +A  ++
Sbjct: 253  PQNASTLINETPNHYKVIKQSRHADYIV 280



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 29/115 (25%), Positives = 45/115 (39%), Gaps = 7/115 (6%)

Query: 412 DCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
           DC   G+P P V W  N +    RD      L      + L +  V  SD+G  TC   N
Sbjct: 138 DCSADGKPRPTVVWLKNGKPFFKRDGVE---LSLRPYQYVLRLRGVVSSDNGQYTCNVSN 194

Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
                +    ++V ++E   +   ++    +  R G+ V L   A+    PR  W
Sbjct: 195 SCDWISRTFTVHVKKREP--SKPLIQIIPNVTARNGDNVTLKCNAMSDSMPRFRW 247



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 19/52 (36%), Positives = 24/52 (46%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
           G PRP V W KNG+     +  E+        LR+R    SD+G YT    N
Sbjct: 143 GKPRPTVVWLKNGKPFFKRDGVELSLRPYQYVLRLRGVVSSDNGQYTCNVSN 194



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 3708 PEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVH-TLNDFGFIALDIDYIYARDAG 3766
            P+   ++ DC  +  G P   + W  NG+PF     V  +L  + ++ L +  + + D G
Sbjct: 130  PDRAIINLDCSAD--GKPRPTVVWLKNGKPFFKRDGVELSLRPYQYV-LRLRGVVSSDNG 186

Query: 3767 EYTCRATNK--WGSATTTAKI 3785
            +YTC  +N   W S T T  +
Sbjct: 187  QYTCNVSNSCDWISRTFTVHV 207



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRL-TTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P+  V WL+NG P    + +  ++  + YV L ++ V   D+G YTC   N       
Sbjct: 143  GKPRPTVVWLKNGKPFFKRDGVELSLRPYQYV-LRLRGVVSSDNGQYTCNVSNSCDWISR 201

Query: 1797 SSTLFVQSK 1805
            + T+ V+ +
Sbjct: 202  TFTVHVKKR 210



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 3591 VEWFHNGKPLLTGSRVK-TINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            V W  NGKP      V+ ++  + +V L + GV   D G YTC  +N     + +  + V
Sbjct: 149  VVWLKNGKPFFKRDGVELSLRPYQYV-LRLRGVVSSDNGQYTCNVSNSCDWISRTFTVHV 207

Query: 3650 KGRQ 3653
            K R+
Sbjct: 208  KKRE 211


>SB_9034| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1756

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 35/138 (25%), Positives = 58/138 (42%), Gaps = 13/138 (9%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   I P  ++ +  G  ++ +C   G P+PT+ W KG ++I   + F +        + 
Sbjct: 769  PTTAINPDAERTLNIGDNLQLNCSATGCPIPTLTWLKGSQIIDRGRGFAL-------PIN 821

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVY-EGQPAQF 4740
            I  A   DEG+Y+C+A N         +++V        +P +T  +    + EG  A  
Sbjct: 822  ILNAQLSDEGEYRCIADNGVSGGHPRQQIRVVV-----RIPVITSEQSSHSFNEGDQASL 876

Query: 4741 KTQITSKIKPTIQWLREG 4758
                T    P I W R G
Sbjct: 877  YCNATGYPTPNINWTRLG 894



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 12/129 (9%)

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
           +R +  G   + +C  TG P P +TW    + I       + +N        I N  LSD
Sbjct: 778 ERTLNIGDNLQLNCSATGCPIPTLTWLKGSQIIDRGRGFALPIN--------ILNAQLSD 829

Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPT 519
            G   C+A N       + ++ V+    V  P      S+ +  EG+   L   A G PT
Sbjct: 830 EGEYRCIADNGVSGGHPRQQIRVV----VRIPVITSEQSSHSFNEGDQASLYCNATGYPT 885

Query: 520 PRITWQKDG 528
           P I W + G
Sbjct: 886 PNINWTRLG 894



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           S S V+ C A+NK+G       +N IE E +  P    + S+L    G    L+  A G 
Sbjct: 44  SGSNVLRCDAQNKAGSDTET--INSIEIEGI--PVITSKQSSLTFNNGGQAFLHCNATGY 99

Query: 518 PTPRITWQKDG 528
           PTP +TW + G
Sbjct: 100 PTPNVTWIRLG 110



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 39/116 (33%), Positives = 48/116 (41%), Gaps = 18/116 (15%)

Query: 410 RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV--VTCVA 467
           R  C  T +P      F  D       N +I    SGN    IT VTLS  G    TCV 
Sbjct: 353 RLSCISTSKPAATKFTFYKD-------NVEIANTSSGN----IT-VTLSTQGTHQFTCVP 400

Query: 468 RNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
            N +G T     + V+ K     P    + ++L   EGE   LN  A G PTP +T
Sbjct: 401 ENVAG-TGENATVTVLVKG---VPVITSKKTSLTFNEGESATLNCNATGYPTPEVT 452



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 1/67 (1%)

Query: 4083 SIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRV 4142
            SIE I   E   +V  E   +  K    PV  S   ++T  EG+ A F C  TG P P V
Sbjct: 221  SIE-IEGKERKSKVRKENRRQGKKIEGIPVITSKLSSLTFNEGDQASFHCNATGFPTPNV 279

Query: 4143 MWLLNGN 4149
             W+  G+
Sbjct: 280  TWIRLGD 286



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 9/96 (9%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G N+ L C     G P   + W    + +  G  F        + ++I++A  +D GEY 
Sbjct: 784  GDNLQLNC--SATGCPIPTLTWLKGSQIIDRGRGFA-------LPINILNAQLSDEGEYR 834

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQ 1287
              A N +   H    +RV+ R  ++T  Q+  +  +
Sbjct: 835  CIADNGVSGGHPRQQIRVVVRIPVITSEQSSHSFNE 870



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 8/79 (10%)

Query: 265 PPKIAQKPRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           PP  A  P   + L  G + Q     +G P P +TW K G ++I+  +   +       +
Sbjct: 768 PPTTAINPDAERTLNIGDNLQLNCSATGCPIPTLTWLK-GSQIIDRGRGFAL------PI 820

Query: 324 RVRNTQKSDSGHYTLLAEN 342
            + N Q SD G Y  +A+N
Sbjct: 821 NILNAQLSDEGEYRCIADN 839



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 10/84 (11%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            + T   +   P    +   N+ + F       G P + + W R+G P+            
Sbjct: 581  IATVTVLVKAPFTASQFTVNETSDFSLHCDVTGSPPVSITWSRHGEPLLVQGAW------ 634

Query: 1766 GYVALNMKYVNPEDSGTYTCRAIN 1789
                LNM  V P   G YTCRA N
Sbjct: 635  ----LNMTSVTPVHEGVYTCRADN 654



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 23/140 (16%)

Query: 4511 IVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            +V   FT +   VN TS   +  D  VTG+ P+ + W ++G+          L   G + 
Sbjct: 587  LVKAPFTASQFTVNETSDFSLHCD--VTGSPPVSITWSRHGEP---------LLVQGAW- 634

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L +    P   G Y C A N  G+     E  V + A   KP+  T   NA         
Sbjct: 635  LNMTSVTPVHEGVYTCRADN--GDECASHERSVQI-AVNFKPRNTTLLTNA--------S 683

Query: 4631 DKIVAEGQAIEFSCKIVGKP 4650
            D  V +G+++  SC+   KP
Sbjct: 684  DVTVLQGKSLALSCESRAKP 703



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 13/38 (34%), Positives = 19/38 (50%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
           P    + S+L   EG+    +  A G PTP +TW + G
Sbjct: 248 PVITSKLSSLTFNEGDQASFHCNATGFPTPNVTWIRLG 285



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            PV  S   ++T   G  A   C  TG+P P V W+  G+
Sbjct: 73   PVITSKQSSLTFNNGGQAFLHCNATGYPTPNVTWIRLGD 111



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 13/83 (15%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V + +    +C +T  P P VTWF        D    ++    GN + ++   T + SGV
Sbjct: 995  VRKNETVTLEC-ITSLPSPHVTWF--------DVQGVVI----GNQSSLVFVATNTSSGV 1041

Query: 463  VTCVARNKSGETAFQCRLNVIEK 485
             TC  R+ +G T     + ++++
Sbjct: 1042 YTCAVRSTAGRTVNSSAVVLVQR 1064


>SB_3465| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 477

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 53/185 (28%), Positives = 78/185 (42%), Gaps = 28/185 (15%)

Query: 392 PQFVKVCQDRDVTEGKMT-RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHAL 450
           P  +    D+ V E   + +  C   G P P VTW       RD     ++   S  H+ 
Sbjct: 3   PSILSKSPDQTVNETTGSLKLTCISDGYPSPTVTWS------RDGV---VVSRTSVYHS- 52

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
              +VT S++G  TC A N  G      ++ V  K ++V+       ST+N    +  VL
Sbjct: 53  --NSVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVS-------STINTSSWDRKVL 103

Query: 511 N--ARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQ 566
           +   +A G P P+ITW    G PI       +    G S L +   + A D   Y+C A 
Sbjct: 104 SLQCKARGVPLPQITWYNPGGQPITAG----VSPISGGSQLQVTTTQDAGDYGQYKCRAS 159

Query: 567 NVAGS 571
           N+ GS
Sbjct: 160 NLLGS 164



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 14/118 (11%)

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
            +++GTY+C ATN  G    +V++     +   KP   +   N     D +    +C    
Sbjct: 58   SEAGTYTCTATNAMGSDTTTVQV-----TVNYKPEMVSSTINTSSW-DRKVLSLQCKARG 111

Query: 3176 VDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231
            V  P  +I WY+  GQP+  +  +  +S  G   L +  TQ+  D G+Y CRA N  G
Sbjct: 112  VPLP--QITWYNPGGQPI--TAGVSPIS--GGSQLQVTTTQDAGDYGQYKCRASNLLG 163



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 16/31 (51%), Positives = 22/31 (70%)

Query: 3764 DAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            +AG YTC ATN  GS TTT ++T + K ++V
Sbjct: 59   EAGTYTCTATNAMGSDTTTVQVTVNYKPEMV 89



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 16/39 (41%), Positives = 26/39 (66%)

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011
            SVT  +AG YTC A NA+G  TT+  +T+  K ++++ +
Sbjct: 54   SVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSST 92



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 4/69 (5%)

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL-KKIQELEKYERPKPIEE-- 2102
            + GTY C ATNA+G   TT  V V+ K  +   T++     +K+  L+   R  P+ +  
Sbjct: 59   EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTINTSSWDRKVLSLQCKARGVPLPQIT 118

Query: 2103 -EQPGQRPV 2110
               PG +P+
Sbjct: 119  WYNPGGQPI 127



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 14/48 (29%), Positives = 27/48 (56%)

Query: 2705 NSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGESLHPDSLDR 2752
            NS+   ++G YTC ATN +G   +T  + +  +  ++  +++  S DR
Sbjct: 53   NSVTRSEAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTINTSSWDR 100



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 21/183 (11%)

Query: 4623 PEIIEPLKDKIVAEGQ-AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P I+    D+ V E   +++ +C   G P PTV W + D ++       +SRT+  ++  
Sbjct: 3    PSILSKSPDQTVNETTGSLKLTCISDGYPSPTVTWSR-DGVV-------VSRTSVYHSNS 54

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            ++ +   + G Y C A N+ G  T   ++ V    +  +    T   D  V        +
Sbjct: 55   VTRS---EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTINTSSWDRKV-----LSLQ 106

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEE-DTGTFTCRATTAAG 4800
             +      P I W   G   P T     I  G+   L +  T +  D G + CRA+   G
Sbjct: 107  CKARGVPLPQITWYNPGGQ-PITAGVSPISGGSQ--LQVTTTQDAGDYGQYKCRASNLLG 163

Query: 4801 QVE 4803
             VE
Sbjct: 164  SVE 166



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 11/64 (17%)

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLV 4809
            PT+ W R+G ++  T     ++  N+           + GT+TC AT A G   T+ ++ 
Sbjct: 33   PTVTWSRDGVVVSRTS----VYHSNSVT-------RSEAGTYTCTATNAMGSDTTTVQVT 81

Query: 4810 VKSK 4813
            V  K
Sbjct: 82   VNYK 85



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 13/42 (30%), Positives = 25/42 (59%)

Query: 1513 DSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRSTQNEAGLEQ 1554
            ++G YTC A N +G+D  + ++T     ++V ST N +  ++
Sbjct: 59   EAGTYTCTATNAMGSDTTTVQVTVNYKPEMVSSTINTSSWDR 100



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/85 (25%), Positives = 33/85 (38%), Gaps = 2/85 (2%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            N  PE++    +    + + +   CK  G PLP + WY        +    +S  +    
Sbjct: 83   NYKPEMVSSTINTSSWDRKVLSLQCKARGVPLPQITWYNPGGQPITAGVSPISGGSQLQV 142

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRV 4704
                +A   D G YKC A N  G V
Sbjct: 143  TTTQDA--GDYGQYKCRASNLLGSV 165


>SB_22798| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 3255

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 49/199 (24%), Positives = 78/199 (39%), Gaps = 28/199 (14%)

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLIL 4574
            SF +  ++  V +G    L     G       W++NG  +              Y  +I 
Sbjct: 2323 SFDVPPRSGTVVAGNPWTLKCSAKGNTSPQYRWMRNGLYLNS------FSNQSDY--VIA 2374

Query: 4575 EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV 4634
            +A  +D+G Y C+A + AG  +  A  ++                N  PEI    +D  V
Sbjct: 2375 KATREDAGVYACLATSEAGLIQSSAATLI---------------VNVKPEITHHPEDSSV 2419

Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694
              G      C+  G P P+ +W+K +++I      Q    +D   L + +   +DE  Y 
Sbjct: 2420 ELGGTATLECRASGVPEPSYRWFKNNEVIPSVGGIQ----SDRPVLVLRDVIAQDESPYY 2475

Query: 4695 CVAYNSAGRV-TVAAKLKV 4712
            C A N AG   +  A LKV
Sbjct: 2476 CQASNDAGTAKSNIATLKV 2494



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 13/138 (9%)

Query: 4459 IHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTL 4518
            +++FS +S  +I +   ED+ V+A +A +  G  + SA  ++           V P  T 
Sbjct: 2362 LNSFSNQSDYVIAKATREDAGVYACLATSEAGLIQSSAATLIVN---------VKPEITH 2412

Query: 4519 TAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP 4578
              ++ +V  G    L+ + +G       W KN  +V P +    ++ D    L++ +   
Sbjct: 2413 HPEDSSVELGGTATLECRASGVPEPSYRWFKN-NEVIPSVGG--IQSDRP-VLVLRDVIA 2468

Query: 4579 QDSGKYECVAINSAGEAR 4596
            QD   Y C A N AG A+
Sbjct: 2469 QDESPYYCQASNDAGTAK 2486



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 40/179 (22%), Positives = 71/179 (39%), Gaps = 18/179 (10%)

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
            P +   V  G      C   G   P  +W +         Y        +Y   I++A  
Sbjct: 2327 PPRSGTVVAGNPWTLKCSAKGNTSPQYRWMRN------GLYLNSFSNQSDYV--IAKATR 2378

Query: 4688 EDEGDYKCVAYNSAGRV-TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
            ED G Y C+A + AG + + AA L V    +  + P      D  V  G  A  + + + 
Sbjct: 2379 EDAGVYACLATSEAGLIQSSAATLIVNVKPEITHHP-----EDSSVELGGTATLECRASG 2433

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETS 4805
              +P+ +W +   +IP     Q     +  VL++ +   +D   + C+A+  AG  +++
Sbjct: 2434 VPEPSYRWFKNNEVIPSVGGIQ----SDRPVLVLRDVIAQDESPYYCQASNDAGTAKSN 2488



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 42/169 (24%), Positives = 60/169 (35%), Gaps = 17/169 (10%)

Query: 403  VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
            V  G      C   G   P+  W  N   +    N    V         I   T  D+GV
Sbjct: 2333 VVAGNPWTLKCSAKGNTSPQYRWMRNGLYLNSFSNQSDYV---------IAKATREDAGV 2383

Query: 463  VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
              C+A +++G         ++     V P+        +V  G    L  RA G P P  
Sbjct: 2384 YACLATSEAGLIQSSAATLIVN----VKPEITHHPEDSSVELGGTATLECRASGVPEPSY 2439

Query: 523  TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             W K+   +IP+    I +D     L +    A D + Y C A N AG+
Sbjct: 2440 RWFKNN-EVIPSVG-GIQSD--RPVLVLRDVIAQDESPYYCQASNDAGT 2484



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 8/105 (7%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            VN  P  IT     + +  G +A  ECR    P+P+ R  W+ N +V+ S    ++    
Sbjct: 2404 VNVKPE-ITHHPEDSSVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDR-- 2458

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQAVSSI-RLNVQSKESII 1943
                L +  V  +D   Y C+A N+ G A S+I  L V   ES++
Sbjct: 2459 --PVLVLRDVIAQDESPYYCQASNDAGTAKSNIATLKVYGGESLV 2501



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 12/128 (9%)

Query: 3117 DSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            D+G Y+C AT++ G  + S     V+     KP  T H ++   ++ G +A  EC    V
Sbjct: 2380 DAGVYACLATSEAGLIQSSAATLIVN----VKPEITHHPED-SSVELGGTATLECRASGV 2434

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFTR 3236
             +P  +  W+ N + +     I+  SD   +VL     Q  D   Y C+A N  G   + 
Sbjct: 2435 PEPSYR--WFKNNEVIPSVGGIQ--SDRPVLVLRDVIAQ--DESPYYCQASNDAGTAKSN 2488

Query: 3237 -ATINCYG 3243
             AT+  YG
Sbjct: 2489 IATLKVYG 2496



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 8/85 (9%)

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
            P R   V  G P   K        P  +W+R G  +            N +  +I     
Sbjct: 2327 PPRSGTVVAGNPWTLKCSAKGNTSPQYRWMRNGLYLNSF--------SNQSDYVIAKATR 2378

Query: 4786 EDTGTFTCRATTAAGQVETSAKLVV 4810
            ED G + C AT+ AG +++SA  ++
Sbjct: 2379 EDAGVYACLATSEAGLIQSSAATLI 2403



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 11/129 (8%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYM 2183
            G  A  ECR   + +P  +  WF N + I +    ++      V  D++   A+D   Y 
Sbjct: 2422 GGTATLECRASGVPEP--SYRWFKNNEVIPSVGGIQSDRPV-LVLRDVI---AQDESPYY 2475

Query: 2184 CKATNKLGEA-VNTCTLKVAGHRNII---LDTQHPNGLEKIRQLEAQG-HSTRIEVEEPK 2238
            C+A+N  G A  N  TLKV G  +++   +   + N  +K    + Q   +  ++  E K
Sbjct: 2476 CQASNDAGTAKSNIATLKVYGGESLVALEVSVSNSNRAKKCNIFDIQAFKAALVKAIEAK 2535

Query: 2239 ISPPRFVTE 2247
            ++   +  E
Sbjct: 2536 VTIANYTAE 2544



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            IV+  P+     +  +VE       ECR     +P  R  W++N +++PS    ++   +
Sbjct: 2403 IVNVKPEITHHPEDSSVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDRPV 2460

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911
              V  D++   A+D   Y C+A ND G
Sbjct: 2461 -LVLRDVI---AQDESPYYCQASNDAG 2483



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 4/66 (6%)

Query: 4428 ARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAEN 4487
            A  E    G P P  +W++ N  I +    Q    S + +L++R V  +D + +   A N
Sbjct: 2425 ATLECRASGVPEPSYRWFKNNEVIPSVGGIQ----SDRPVLVLRDVIAQDESPYYCQASN 2480

Query: 4488 RGGTAK 4493
              GTAK
Sbjct: 2481 DAGTAK 2486



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 14/39 (35%), Positives = 21/39 (53%)

Query: 266  PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQ 304
            P+I   P +S ++ G  A  + + SG P P   WFKN +
Sbjct: 2408 PEITHHPEDSSVELGGTATLECRASGVPEPSYRWFKNNE 2446



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 7/100 (7%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            PE T  P D  +    +A  ECR   V + S R  WF N + + +   +++       +L
Sbjct: 2408 PEITHHPEDSSVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDRP----VL 2461

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVS-CKLQVKGRQGII 3656
             +  V  +D   Y C+A+N  G A  +   L+V G + ++
Sbjct: 2462 VLRDVIAQDESPYYCQASNDAGTAKSNIATLKVYGGESLV 2501



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 6/72 (8%)

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
            +++ G TA  +CR   V +P+ +  WF+N ++I     I          + +  V  +DE
Sbjct: 2418 SVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDRPV----LVLRDVIAQDE 2471

Query: 2447 GVYMCRASNLLG 2458
              Y C+ASN  G
Sbjct: 2472 SPYYCQASNDAG 2483



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 7/86 (8%)

Query: 1325 GTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYT 1384
            G    LECR   V + + R  WF N + I +        + D   L L  V  +D   Y 
Sbjct: 2422 GGTATLECRASGVPEPSYR--WFKNNEVIPSVG----GIQSDRPVLVLRDVIAQDESPYY 2475

Query: 1385 CQATNQLGEAVTSCA-LRVIAKKDLI 1409
            CQA+N  G A ++ A L+V   + L+
Sbjct: 2476 CQASNDAGTAKSNIATLKVYGGESLV 2501



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 13/91 (14%)

Query: 1440 VTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV-TIG--HRFRPI 1496
            V +KP     P+   +V  G     EC+   V + + +  WFKN + + ++G     RP+
Sbjct: 2404 VNVKPEITHHPED-SSVELGGTATLECRASGVPEPSYR--WFKNNEVIPSVGGIQSDRPV 2460

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGT 1527
                   L + D+IA+D   Y C+A N  GT
Sbjct: 2461 -------LVLRDVIAQDESPYYCQASNDAGT 2484



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 26/100 (26%), Positives = 38/100 (38%), Gaps = 6/100 (6%)

Query: 392  PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
            P+     +D  V  G     +CR +G P P   WF N+  I       +   +S    L+
Sbjct: 2408 PEITHHPEDSSVELGGTATLECRASGVPEPSYRWFKNNEVI-----PSVGGIQSDRPVLV 2462

Query: 452  ITNVTLSDSGVVTCVARNKSGETAFQ-CRLNVIEKEQVVA 490
            + +V   D     C A N +G        L V   E +VA
Sbjct: 2463 LRDVIAQDESPYYCQASNDAGTAKSNIATLKVYGGESLVA 2502


>SB_56900| Best HMM Match : I-set (HMM E-Value=8e-10)
          Length = 968

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 11/120 (9%)

Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
           +VT S++G  TC A N+ G      ++ V  K ++V+      F    +     + L  +
Sbjct: 54  SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKI-----LSLQCK 108

Query: 514 AVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQNVAGS 571
           A G P+P+ITW K  G PI       +    G S L +   + A D   Y+C A N+ GS
Sbjct: 109 ARGVPSPQITWYKPGGQPITAG----VSPISGGSQLQVTTTREAGDFGQYKCQASNLLGS 164



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 18/37 (48%), Positives = 25/37 (67%)

Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            D +   +AG YTC ATN+ GS TTT ++T + K +IV
Sbjct: 53   DSVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIV 89



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 16/39 (41%), Positives = 25/39 (64%)

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011
            SVT  +AG YTC A N +G  TT+  +T+  K +I++ +
Sbjct: 54   SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSST 92



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 14/118 (11%)

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
            +++GTY+C ATN+ G    +V++     +   KP   +   N     + +    +C    
Sbjct: 58   SEAGTYTCTATNEMGSDTTTVQV-----TVNYKPEIVSSTTN-TSFWNKKILSLQCKARG 111

Query: 3176 VDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231
            V  P  +I WY   GQP+  +  +  +S  G   L +  T+   D G+Y C+A N  G
Sbjct: 112  VPSP--QITWYKPGGQPI--TAGVSPIS--GGSQLQVTTTREAGDFGQYKCQASNLLG 163



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL-KKIQELEKYER--PKP-IE 2101
            + GTY C ATN +G   TT  V V+ K  +   T +     KKI  L+   R  P P I 
Sbjct: 59   EAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKILSLQCKARGVPSPQIT 118

Query: 2102 EEQPGQRPV 2110
              +PG +P+
Sbjct: 119  WYKPGGQPI 127



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 1476 LKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE-DSGIYTCRAVNLVGTDEVSCRL 1534
            LK+    +G P       R   +    ++   D +   ++G YTC A N +G+D  + ++
Sbjct: 21   LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEMGSDTTTVQV 80

Query: 1535 TCRSTTDIVRSTQN 1548
            T     +IV ST N
Sbjct: 81   TVNYKPEIVSSTTN 94



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY-EEDSGIYTCKATNSKGSATTS 2860
            LK+    +  P P+ T  +   + S  S+  + +    ++G YTC ATN  GS TT+
Sbjct: 21   LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEMGSDTTT 77



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/85 (28%), Positives = 32/85 (37%), Gaps = 2/85 (2%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            N  PEI+    +      + +   CK  G P P + WYK       +    +S  +    
Sbjct: 83   NYKPEIVSSTTNTSFWNKKILSLQCKARGVPSPQITWYKPGGQPITAGVSPISGGSQLQV 142

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRV 4704
                EA   D G YKC A N  G V
Sbjct: 143  TTTREA--GDFGQYKCQASNLLGSV 165



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 9/120 (7%)

Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVS-----PPKIAQKPRNSKLQEGADAQFQVQ 288
           V + +S+T+   G      + E+      V       P+I     N+          Q +
Sbjct: 49  VYYSDSVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKILSLQCK 108

Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS-DSGHYTLLAENPNGCI 347
             G P P++TW+K G + I +    I      + L+V  T+++ D G Y   A N  G +
Sbjct: 109 ARGVPSPQITWYKPGGQPITAGVSPI---SGGSQLQVTTTREAGDFGQYKCQASNLLGSV 165



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 14/43 (32%), Positives = 25/43 (58%)

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
            SV   ++G YTC ATN++G   T+  + V  K +++  + + S
Sbjct: 54   SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTS 96


>SB_54071| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 266

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 7/78 (8%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P   I P  D+ +  G  ++ +C   G P+PT+ W KG ++I   + F +        + 
Sbjct: 180  PTTAISPDADRTLNIGDNLQLNCSATGCPIPTLTWLKGSQIIARGRGFAL-------PIN 232

Query: 4682 ISEAFPEDEGDYKCVAYN 4699
            IS A   DEG+Y+C+A N
Sbjct: 233  ISNAQLSDEGEYRCIADN 250



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 49/213 (23%), Positives = 83/213 (38%), Gaps = 16/213 (7%)

Query: 357 SPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVT 416
           +P    V   R+    +    E   +I ++ K      +    D    +GK     C   
Sbjct: 52  TPVREGVYTCRADNGDECASHERSVQIAVNFKPRNTTLLTNASDVTALQGKSLALSCESR 111

Query: 417 GRPYP-EVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK-SGET 474
            +P   + T++ +D  +        +  E    +L+I +V    +    C+++N  SG +
Sbjct: 112 AKPSSCDFTFYQDDVAL---VTLPGICEEGSVTSLVINSVRGCGNTTFACLSKNMISGGS 168

Query: 475 AFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPN 534
                L + +          +R  TLN+  G+ + LN  A G P P +TW K G  II  
Sbjct: 169 WSNITLEIQDPPTTAISPDADR--TLNI--GDNLQLNCSATGCPIPTLTWLK-GSQIIAR 223

Query: 535 PELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
                   G A  ++I  A+ SD   Y+C A N
Sbjct: 224 GR------GFALPINISNAQLSDEGEYRCIADN 250



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 8/79 (10%)

Query: 265 PPKIAQKPRNSK-LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
           PP  A  P   + L  G + Q     +G P P +TW K  Q +       +        +
Sbjct: 179 PPTTAISPDADRTLNIGDNLQLNCSATGCPIPTLTWLKGSQIIARGRGFAL-------PI 231

Query: 324 RVRNTQKSDSGHYTLLAEN 342
            + N Q SD G Y  +A+N
Sbjct: 232 NISNAQLSDEGEYRCIADN 250



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/65 (30%), Positives = 26/65 (40%), Gaps = 10/65 (15%)

Query: 1725 NQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYT 1784
            N+ + F       G P + + W R+G P+                LNM  V P   G YT
Sbjct: 11   NETSDFSLHCDVTGSPPVSITWSRHGEPLLVQGAW----------LNMTSVTPVREGVYT 60

Query: 1785 CRAIN 1789
            CRA N
Sbjct: 61   CRADN 65


>SB_33923| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 221

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 34/105 (32%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 4513 PPSFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYT 4570
            PP  ++T A   N+  G         TG  P   Y WL NGK +    R  I   DG  +
Sbjct: 2    PPEVSVTPAITTNIAIGSTYYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSS 61

Query: 4571 LLILEAYPQDSGKYECVAINSAGEAR-CDAECVVSLPATKDKPKP 4614
            L ++ A  +DSG Y CVA N  G     +  C + + A  +  KP
Sbjct: 62   LEVINATREDSGSYACVAENIKGTGNPSEPSCQLQVRAPGEACKP 106



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 7/112 (6%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVND-SSMRVEWFHNGKPLLTGSRVKTINDF-GF 3614
            PPE + TP+        S ++ C  +      +    W HNGKPL    R+ TI  F G 
Sbjct: 2    PPEVSVTPAITTNIAIGSTYY-CTCVATGIYPTQSYAWLHNGKPLNASGRI-TIETFDGK 59

Query: 3615 VILEIGGVYQRDAGLYTCKATNRHG---EATVSCKLQVKGRQGIILEPQLPS 3663
              LE+    + D+G Y C A N  G    +  SC+LQV+        PQ  S
Sbjct: 60   SSLEVINATREDSGSYACVAENIKGTGNPSEPSCQLQVRAPGEACKPPQFNS 111



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 26/83 (31%), Positives = 39/83 (46%)

Query: 636 PPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYIS 695
           PP+  V     T +  G  ++ T +     PT    WL NG+ + AS R T     G  S
Sbjct: 2   PPEVSVTPAITTNIAIGSTYYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSS 61

Query: 696 LDMLSLNIQDSGEYTCRAVSATG 718
           L++++   +DSG Y C A +  G
Sbjct: 62  LEVINATREDSGSYACVAENIKG 84



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 31/108 (28%), Positives = 46/108 (42%), Gaps = 6/108 (5%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDF-GYV 1502
            P     P    N+  G   +  C    +  +     W  NG+P+    R   I  F G  
Sbjct: 3    PEVSVTPAITTNIAIGSTYYCTCVATGIYPTQ-SYAWLHNGKPLNASGRIT-IETFDGKS 60

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGT---DEVSCRLTCRSTTDIVRSTQ 1547
            +L++I+   EDSG Y C A N+ GT    E SC+L  R+  +  +  Q
Sbjct: 61   SLEVINATREDSGSYACVAENIKGTGNPSEPSCQLQVRAPGEACKPPQ 108



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 20/52 (38%), Positives = 27/52 (51%)

Query: 1608 TLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALG 1659
            T    W HN KPL +  R T     G  +L++++   EDSG+Y C A N  G
Sbjct: 33   TQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 499 TLNVREGEPVVLNARAVGT-PTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           T N+  G        A G  PT    W  +G P+  +  + I T  G S+L++  A   D
Sbjct: 12  TTNIAIGSTYYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATRED 71

Query: 558 AAWYQCTAQNVAGS 571
           +  Y C A+N+ G+
Sbjct: 72  SGSYACVAENIKGT 85



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 2241 PPRFVTELRGTTHVFEGKTAHFECQVEPVHDPNLRIEFYHNGKALQSAARFHI-TFDFGY 2299
            PP        TT++  G T +  C    ++ P     + HNGK L ++ R  I TFD G 
Sbjct: 2    PPEVSVTPAITTNIAIGSTYYCTCVATGIY-PTQSYAWLHNGKPLNASGRITIETFD-GK 59

Query: 2300 VSLDIQHCVPEDAGEYSVKAINALG 2324
             SL++ +   ED+G Y+  A N  G
Sbjct: 60   SSLEVINATREDSGSYACVAENIKG 84



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 5/83 (6%)

Query: 3047 PPEFTTVFKDIVDISEGQIAHYEASLIPTGDQ-SMVIEWFYNGKTIEASHRIRTVYAF-G 3104
            PPE +       +I+ G    Y  + + TG   +    W +NGK + AS RI T+  F G
Sbjct: 2    PPEVSVTPAITTNIAIGST--YYCTCVATGIYPTQSYAWLHNGKPLNASGRI-TIETFDG 58

Query: 3105 MVVLEILGTKTTDSGTYSCRATN 3127
               LE++     DSG+Y+C A N
Sbjct: 59   KSSLEVINATREDSGSYACVAEN 81



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 21/58 (36%), Positives = 26/58 (44%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGSATTS 2860
            PT    W  N KPL +  R          SL++ +   EDSG Y C A N KG+   S
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPS 89



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 21/53 (39%), Positives = 28/53 (52%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLG 852
           PT    W  +G+P+ AS RIT     G  SL +++   ED+GSY   A N  G
Sbjct: 32  PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 1/64 (1%)

Query: 3169 FECTVVPVDD-PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
            + CT V     P     W HNG+P+  S RI   +  G   L++      DSG Y C A 
Sbjct: 21   YYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAE 80

Query: 3228 NKYG 3231
            N  G
Sbjct: 81   NIKG 84



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 19/58 (32%), Positives = 28/58 (48%)

Query: 1207 PTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHTS 1264
            PT    W HNG+ +    R       G  +L++I+AT  D+G Y   A N  G+ + S
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPS 89



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 21/53 (39%), Positives = 26/53 (49%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELG 1792
            P     WL NG P+ AS R+T     G  +L +     EDSG+Y C A N  G
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKT-TYDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
            PT    W  NG+P+    R    T+D G  +L+++ A  ED+G+Y C A N  G
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFD-GKSSLEVINATREDSGSYACVAENIKG 84



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 20/52 (38%), Positives = 27/52 (51%)

Query: 945 WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
           WL +G+P+ AS RIT     G  +L + + T  D+G Y C A N  G    S
Sbjct: 38  WLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPS 89



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 3/86 (3%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF-GF 3752
            PP  +V      ++  G   +  C    +  PT    W HNG+P     R+ T+  F G 
Sbjct: 2    PPEVSVTPAITTNIAIGSTYYCTCVATGIY-PTQSYAWLHNGKPLNASGRI-TIETFDGK 59

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGS 3778
             +L++      D+G Y C A N  G+
Sbjct: 60   SSLEVINATREDSGSYACVAENIKGT 85



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 3/73 (4%)

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT-KTHDFGYVSMTISHVRDED 2445
            NI  G T +  C    +  PT    W  N K +  S RIT +T D G  S+ + +   ED
Sbjct: 14   NIAIGSTYYCTCVATGIY-PTQSYAWLHNGKPLNASGRITIETFD-GKSSLEVINATRED 71

Query: 2446 EGVYMCRASNLLG 2458
             G Y C A N+ G
Sbjct: 72   SGSYACVAENIKG 84



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 18/53 (33%), Positives = 26/53 (49%)

Query: 2139 PHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLG 2191
            P  +  W HNG+ + A  R       G  +L+++    EDSG+Y C A N  G
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 18/52 (34%), Positives = 26/52 (50%)

Query: 1074 TMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAG 1125
            T +  W  NGK + ++ RI      G  +L++ +   EDSG Y  VA N  G
Sbjct: 33   TQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 18/53 (33%), Positives = 24/53 (45%)

Query: 1874 PNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
            P     W  NGK L +  R       G ++L+++    EDSG Y C A N  G
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 27/83 (32%), Positives = 31/83 (37%), Gaps = 1/83 (1%)

Query: 4438 PLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSAN 4497
            P     W     P+  S    I TF  KS L +     EDS  +A VAEN  GT   S  
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPSEP 91

Query: 4498 LVVEEKRRQGRGGIVPPSFTLTA 4520
                + R  G     PP F   A
Sbjct: 92   SCQLQVRAPGE-ACKPPQFNSIA 113



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 19/53 (35%), Positives = 25/53 (47%)

Query: 293 PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           P     W  NG+ L  S +  I T    ++L V N  + DSG Y  +AEN  G
Sbjct: 32  PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 17/53 (32%), Positives = 25/53 (47%)

Query: 2941 PDLKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRG 2993
            P     W  NGK L    R  + +  G  +L++++    DSG Y C A N +G
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 5/84 (5%)

Query: 2672 PNLKIEWFKNGVTLTTGARLK-STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEA-VST 2729
            P     W  NG  L    R+   TFD G  +L + +   +DSG Y C A N+ G    S 
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFD-GKSSLEVINATREDSGSYACVAENIKGTGNPSE 90

Query: 2730 ASIKIEDRHWLLGESLHPDSLDRI 2753
             S +++ R    GE+  P   + I
Sbjct: 91   PSCQLQVR--APGEACKPPQFNSI 112



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 5/106 (4%)

Query: 4622 PPEI-IEPLKDKIVAEGQAIEFSCKIVG-KPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            PPE+ + P     +A G     +C   G  P  +  W    K +  S    +     + +
Sbjct: 2    PPEVSVTPAITTNIAIGSTYYCTCVATGIYPTQSYAWLHNGKPLNASGRITIETFDGKSS 61

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGR---VTVAAKLKVTQPDQADNLP 4722
            L +  A  ED G Y CVA N  G       + +L+V  P +A   P
Sbjct: 62   LEVINATREDSGSYACVAENIKGTGNPSEPSCQLQVRAPGEACKPP 107



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 3/108 (2%)

Query: 1341 TMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLG---EAVTS 1397
            T    W  NGKP+    R          +L++++   EDSG Y C A N  G    +  S
Sbjct: 33   TQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKGTGNPSEPS 92

Query: 1398 CALRVIAKKDLILESQHPSGLEKIQYLEDTSRYKKTDIIDESVTIKPR 1445
            C L+V A  +     Q  S         D     +TD  + S   K R
Sbjct: 93   CQLQVRAPGEACKPPQFNSIAISESECHDCFCMGRTDQCNSSTLYKDR 140



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 19/53 (35%), Positives = 22/53 (41%)

Query: 4003 PNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            P     W  NGKPL    R T     G  ++       EDSG Y C A N+ G
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 20/53 (37%), Positives = 21/53 (39%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYG 3502
            P     W  NGK L A  R       G   LE+     EDSG Y C A N  G
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 2/54 (3%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDF-GIVILDILYCYEENSGEYECVATNKLG 3364
            P     W +NGK L    R  T   F G   L+++    E+SG Y CVA N  G
Sbjct: 32   PTQSYAWLHNGKPLNASGRI-TIETFDGKSSLEVINATREDSGSYACVAENIKG 84



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/50 (36%), Positives = 22/50 (44%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
            P     W  NGK L +  R       G  SL+++    EDSG Y C A N
Sbjct: 32   PTQSYAWLHNGKPLNASGRITIETFDGKSSLEVINATREDSGSYACVAEN 81


>SB_2143| Best HMM Match : ig (HMM E-Value=1.9e-09)
          Length = 306

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 13/125 (10%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L+I NV   D+G       +  GET F+     ++   V+ P  V   + + V +     
Sbjct: 83  LIIKNVQPKDAGEYAMTLVDDGGETTFEASKFTLD---VLVPPSVTH-ANITVNKTNTAE 138

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L   A G PTP +TW + G         + +  G   TL     K SD   Y CTA N  
Sbjct: 139 LTCSATGNPTPNVTWTRSG---------KENVLGTGETLTFSDVKISDGGCYVCTATNNI 189

Query: 570 GSTAT 574
           GS A+
Sbjct: 190 GSGAS 194



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 52/199 (26%), Positives = 76/199 (38%), Gaps = 33/199 (16%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            LII+ V  +D+  +A    + GG     A+    +        +VPPS  +T  N+ V  
Sbjct: 83   LIIKNVQPKDAGEYAMTLVDDGGETTFEASKFTLDV-------LVPPS--VTHANITVNK 133

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLILEAYPQDSGKYEC 4586
                 L    TG    +V W ++GK+        +L   GT  TL   +    D G Y C
Sbjct: 134  TNTAELTCSATGNPTPNVTWTRSGKE-------NVL---GTGETLTFSDVKISDGGCYVC 183

Query: 4587 VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKI 4646
             A N+ G       C+      + KP   T  A      +          G AI  +C  
Sbjct: 184  TATNNIGSGASGTVCL----TVQYKP-VHTNIAGVESYNVRQC-------GAAISLTCSA 231

Query: 4647 VGKP-LPTVQWYKGDKLIK 4664
            VG+P L T   Y  + LI+
Sbjct: 232  VGEPQLITYHLYMDNLLIR 250



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 13/117 (11%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V +       C  TG P P VTW  + ++        +L        L  ++V +SD G 
Sbjct: 131 VNKTNTAELTCSATGNPTPNVTWTRSGKE-------NVL---GTGETLTFSDVKISDGGC 180

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTP 518
             C A N  G  A       ++ + V     +    + NVR+ G  + L   AVG P
Sbjct: 181 YVCTATNNIGSGASGTVCLTVQYKPVHTN--IAGVESYNVRQCGAAISLTCSAVGEP 235



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 15/42 (35%), Positives = 21/42 (50%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            +TV +   A   C  TG+P P V W  +G   V G+   LT+
Sbjct: 129  ITVNKTNTAELTCSATGNPTPNVTWTRSGKENVLGTGETLTF 170



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+Y   + T +  TL I    P+D G+Y     +  G  T  A  K T        P++T
Sbjct: 69   SRYSLSTATFNPITLIIKNVQPKDAGEYAMTLVDDGGETTFEAS-KFTLDVLVP--PSVT 125

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREG 4758
               +I V +   A+     T    P + W R G
Sbjct: 126  H-ANITVNKTNTAELTCSATGNPTPNVTWTRSG 157


>SB_30548| Best HMM Match : I-set (HMM E-Value=2.1e-11)
          Length = 203

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 5/72 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C   G P P+VTW +N+  +R     + +V E     L I N+   D G + CVARN +G
Sbjct: 21  CPTRGLPAPDVTWEMNNTNVRP--GGRFVVQEG---TLTIRNLVKQDQGNIRCVARNAAG 75

Query: 473 ETAFQCRLNVIE 484
           +     +LNVIE
Sbjct: 76  QDTATSKLNVIE 87



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V  G  +   C   G P P V W   +  ++P   F       E TL I     +D+G+ 
Sbjct: 11   VLSGITLTIICPTRGLPAPDVTWEMNNTNVRPGGRF----VVQEGTLTIRNLVKQDQGNI 66

Query: 4694 KCVAYNSAGRVTVAAKLKVTQ 4714
            +CVA N+AG+ T  +KL V +
Sbjct: 67   RCVARNAAGQDTATSKLNVIE 87



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 4525 VTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKY 4584
            V SG  + +     G    DV W  N   V+P    + + ++GT T+  L    QD G  
Sbjct: 11   VLSGITLTIICPTRGLPAPDVTWEMNNTNVRPG--GRFVVQEGTLTIRNL--VKQDQGNI 66

Query: 4585 ECVAINSAGE 4594
             CVA N+AG+
Sbjct: 67   RCVARNAAGQ 76


>SB_45888| Best HMM Match : Pkinase_Tyr (HMM E-Value=1.4e-25)
          Length = 561

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 5/86 (5%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V EG+ +  +C+    P PTV WYK DK    S  +    +    +L IS A  +D+G+Y
Sbjct: 198  VTEGEPVNITCQSNDLPRPTVTWYKDDKPANQSVLWYRGSS----SLVISAASIKDQGEY 253

Query: 4694 KCVAYNSAGRV-TVAAKLKVTQPDQA 4718
             C A N+ G   +    L+VT P  A
Sbjct: 254  FCTAENTYGHAQSNKTNLEVTDPPSA 279



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 36/107 (33%), Positives = 48/107 (44%), Gaps = 6/107 (5%)

Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
           TC      G T+ Q  + VI+     A         LNV EGEPV +  ++   P P +T
Sbjct: 162 TCRTSTDFGCTSGQVYIRVIDPSP--ASLIATPPLYLNVTEGEPVNITCQSNDLPRPTVT 219

Query: 524 WQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           W KD  P   N  +  +   G+S+L I  A   D   Y CTA+N  G
Sbjct: 220 WYKDDKP--ANQSVLWYR--GSSSLVISAASIKDQGEYFCTAENTYG 262



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 14/122 (11%)

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPS 3874
            R+ D P    +++TPP ++       V E E V   C  +  + P+  + WY++ K  P+
Sbjct: 179  RVID-PSPASLIATPPLYLN------VTEGEPVNITC--QSNDLPRPTVTWYKDDK--PA 227

Query: 3875 GHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE-DFTKATISCKKLPDIILQNQV 3933
                  ++  G  SL I     +D GEY C A N +G     K  +     P  + ++Q 
Sbjct: 228  NQS--VLWYRGSSSLVISAASIKDQGEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQA 285

Query: 3934 PR 3935
             R
Sbjct: 286  VR 287



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 5/71 (7%)

Query: 402 DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           +VTEG+     C+    P P VTW+ +D+      N  +L    G+ +L+I+  ++ D G
Sbjct: 197 NVTEGEPVNITCQSNDLPRPTVTWYKDDKPA----NQSVLWYR-GSSSLVISAASIKDQG 251

Query: 462 VVTCVARNKSG 472
              C A N  G
Sbjct: 252 EYFCTAENTYG 262



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 6/57 (10%)

Query: 99  PTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           P P V+W +   P    N+  + Y    G  SL+I      D+GEY CTA N YG A
Sbjct: 214 PRPTVTWYKDDKP---ANQSVLWYR---GSSSLVISAASIKDQGEYFCTAENTYGHA 264



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 12/103 (11%)

Query: 1856 LSEGQSAHYECRIEPYPDPNMRVEWYFNGKVL-QSGHRYRTSNDFGFAALDILTVYGEDS 1914
            ++EG+  +  C+    P P   V WY + K   QS   YR S+    +A  I     +D 
Sbjct: 198  VTEGEPVNITCQSNDLPRPT--VTWYKDDKPANQSVLWYRGSSSLVISAASI-----KDQ 250

Query: 1915 GEYTCKAINNLGQAVSS-IRLNVQSKESIIRDSQ---HESALE 1953
            GEY C A N  G A S+   L V    S +  SQ    ES LE
Sbjct: 251  GEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESGLE 293



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 6/73 (8%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTG 2048
            VTEG PV++      +  PT  V WY + +P  Q       +  G  +L I  A  +D G
Sbjct: 198  VTEGEPVNITCQSNDLPRPT--VTWYKDDKPANQS----VLWYRGSSSLVISAASIKDQG 251

Query: 2049 TYMCKATNAVGEA 2061
             Y C A N  G A
Sbjct: 252  EYFCTAENTYGHA 264



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 7/115 (6%)

Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFG 3751
            P+P          ++V EG PV+  C+   +  PT  + W+ + +P    +    L   G
Sbjct: 183  PSPASLIATPPLYLNVTEGEPVNITCQSNDLPRPT--VTWYKDDKP----ANQSVLWYRG 236

Query: 3752 FIALDIDYIYARDAGEYTCRATNKWGSA-TTTAKITCSAKRDIVLESQLPQGMSG 3805
              +L I     +D GEY C A N +G A +    +  +     V +SQ  +  SG
Sbjct: 237  SSSLVISAASIKDQGEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESG 291



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 7/103 (6%)

Query: 3984 SLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDS 4043
            ++ E E     CQ   +  P   V W+ + KP    N+    Y  G  ++       +D 
Sbjct: 197  NVTEGEPVNITCQSNDL--PRPTVTWYKDDKPA---NQSVLWYR-GSSSLVISAASIKDQ 250

Query: 4044 GEYLCRATNLYG-MDETKAVIKTTGKPGIVYDSQLPKHMKSIE 4085
            GEY C A N YG     K  ++ T  P  V+ SQ  +    +E
Sbjct: 251  GEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESGLE 293



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 4/88 (4%)

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
           R + P     IA  P    + EG       Q +  PRP VTW+K+ +    S    ++  
Sbjct: 179 RVIDPSPASLIATPPLYLNVTEGEPVNITCQSNDLPRPTVTWYKDDKPANQS----VLWY 234

Query: 318 HNHTTLRVRNTQKSDSGHYTLLAENPNG 345
              ++L +      D G Y   AEN  G
Sbjct: 235 RGSSSLVISAASIKDQGEYFCTAENTYG 262



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 5/71 (7%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQA-TTSANLTI 1001
            V W KD +P   S      +  G  +L I + ++ D G Y C A N  G A +   NL +
Sbjct: 218  VTWYKDDKPANQS----VLWYRGSSSLVISAASIKDQGEYFCTAENTYGHAQSNKTNLEV 273

Query: 1002 VTKKDIIAESQ 1012
                  + +SQ
Sbjct: 274  TDPPSAVFKSQ 284



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 7/101 (6%)

Query: 3431 NLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDS 3490
            N+ EGE  +   +    D P   V WY + K       +      G   L IS    +D 
Sbjct: 197  NVTEGEPVNITCQ--SNDLPRPTVTWYKDDKPANQSVLWYR----GSSSLVISAASIKDQ 250

Query: 3491 GEYLCRAYNNYGEAVTT-ASMKVQGKRNIILESQLPKGMEG 3530
            GEY C A N YG A +   +++V    + + +SQ  +   G
Sbjct: 251  GEYFCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESG 291



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 6/72 (8%)

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
            N+ EG+  +  C+   +  PT  V W++++K    S    +    G  S+ IS    +D+
Sbjct: 197  NVTEGEPVNITCQSNDLPRPT--VTWYKDDKPANQSVLWYR----GSSSLVISAASIKDQ 250

Query: 2447 GVYMCRASNLLG 2458
            G Y C A N  G
Sbjct: 251  GEYFCTAENTYG 262



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            +NVT G+ V +  +        V W K+ K         +L   G+ +L+I  A  +D G
Sbjct: 196  LNVTEGEPVNITCQSNDLPRPTVTWYKDDKPAN----QSVLWYRGSSSLVISAASIKDQG 251

Query: 4583 KYECVAINSAGEAR 4596
            +Y C A N+ G A+
Sbjct: 252  EYFCTAENTYGHAQ 265



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 7/100 (7%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG+ ++  C       PT  + W+ ++KP      +         SL I+    +D G Y
Sbjct: 200  EGEPVNITCQSNDLPRPT--VTWYKDDKPANQSVLWYRGSS----SLVISAASIKDQGEY 253

Query: 2847 TCKATNSKGSA-TTSGSLRCTGDKNIYFDTQHPQGKAGLE 2885
             C A N+ G A +   +L  T   +  F +Q  + ++GLE
Sbjct: 254  FCTAENTYGHAQSNKTNLEVTDPPSAVFKSQAVRRESGLE 293



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 5/99 (5%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            + PS   +         V E E      + +  P P + WY+++ P   S    +  +  
Sbjct: 181  IDPSPASLIATPPLYLNVTEGEPVNITCQSNDLPRPTVTWYKDDKPANQS----VLWYRG 236

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAKCS-ANLVVEE 4502
             S L+I    ++D   +   AEN  G A+ +  NL V +
Sbjct: 237  SSSLVISAASIKDQGEYFCTAENTYGHAQSNKTNLEVTD 275


>SB_6364| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 357

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 53/203 (26%), Positives = 76/203 (37%), Gaps = 34/203 (16%)

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT------------- 4679
            I  EG + E +C     P   + WY+ D ++  SK +Q+S++  E               
Sbjct: 9    ISREGVSPEMTCNTTANPSADITWYRDDVMLT-SKRYQISQSVTESQIPRRIQMLCPSKV 67

Query: 4680 --------LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIV 4731
                    L I EA   D G Y C A N  G       L+V  P     +  L P ++  
Sbjct: 68   PHPITQSILVIMEARGSDTGTYTCRARNMMGARDRHVVLRVQVP-----VAILIPHKNQT 122

Query: 4732 VYEGQPAQFKTQITSKIKPTIQWLR-EGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGT 4790
            V EG         +    P I W R +G+ +P        H   N VL + N  +   GT
Sbjct: 123  VLEGNNVTLSCNASGIPAPVITWYRKDGSYMPVN------HRVVNGVLTVFNITKAHEGT 176

Query: 4791 FTCRATTAAGQVETSAKLVVKSK 4813
            + C+A    G   T A L   +K
Sbjct: 177  YVCKAKNVLGAKTTEATLNCNNK 199



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 21/140 (15%)

Query: 4571 LLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK 4630
            L+I+EA   D+G Y C A N  G AR D   V+ +                P  I+ P K
Sbjct: 76   LVIMEARGSDTGTYTCRARNMMG-AR-DRHVVLRV--------------QVPVAILIPHK 119

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
            ++ V EG  +  SC   G P P + WY+     K   Y  ++       L +       E
Sbjct: 120  NQTVLEGNNVTLSCNASGIPAPVITWYR-----KDGSYMPVNHRVVNGVLTVFNITKAHE 174

Query: 4691 GDYKCVAYNSAGRVTVAAKL 4710
            G Y C A N  G  T  A L
Sbjct: 175  GTYVCKAKNVLGAKTTEATL 194



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 54/194 (27%), Positives = 73/194 (37%), Gaps = 31/194 (15%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDD-YNHKILVNESG----------------- 446
           EG      C  T  P  ++TW+ +D  +    Y     V ES                  
Sbjct: 12  EGVSPEMTCNTTANPSADITWYRDDVMLTSKRYQISQSVTESQIPRRIQMLCPSKVPHPI 71

Query: 447 -NHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREG 505
               L+I     SD+G  TC ARN  G       L V     ++ P          V EG
Sbjct: 72  TQSILVIMEARGSDTGTYTCRARNMMGARDRHVVLRVQVPVAILIPH-----KNQTVLEG 126

Query: 506 EPVVLNARAVGTPTPRITW-QKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
             V L+  A G P P ITW +KDG  +  N  +    +G  +  +I +A       Y C 
Sbjct: 127 NNVTLSCNASGIPAPVITWYRKDGSYMPVNHRV---VNGVLTVFNITKAHEGT---YVCK 180

Query: 565 AQNVAGSTATRARL 578
           A+NV G+  T A L
Sbjct: 181 AKNVLGAKTTEATL 194



 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 15/140 (10%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQS 3166
            +L I+  + +D+GTY+CRA N  G  +  V L        Q P         + + +G +
Sbjct: 75   ILVIMEARGSDTGTYTCRARNMMGARDRHVVLRV------QVPVAILIPHKNQTVLEGNN 128

Query: 3167 AHFECTVVPVDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
                C    +  P   I WY  +G  M  + R+        V+     T+ H+ G YVC+
Sbjct: 129  VTLSCNASGIPAP--VITWYRKDGSYMPVNHRV-----VNGVLTVFNITKAHE-GTYVCK 180

Query: 3226 AYNKYGEDFTRATINCYGKG 3245
            A N  G   T AT+NC  KG
Sbjct: 181  AKNVLGAKTTEATLNCNNKG 200



 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 47/214 (21%), Positives = 85/214 (39%), Gaps = 23/214 (10%)

Query: 278 QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEII--TTHNHTTLRVRNTQKSDSGH 335
           +EG   +     + NP   +TW+++   ++ S +++I    T +    R++    S   H
Sbjct: 11  REGVSPEMTCNTTANPSADITWYRDDV-MLTSKRYQISQSVTESQIPRRIQMLCPSKVPH 69

Query: 336 YTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEISEKALAPQFV 395
                  P    +     A  S T +Y    R++ +   + R    R+++    L P   
Sbjct: 70  -------PITQSILVIMEARGSDTGTYTC--RARNMMGARDRHVVLRVQVPVAILIPH-- 118

Query: 396 KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNV 455
              +++ V EG      C  +G P P +TW+  D       NH+++     N  L + N+
Sbjct: 119 ---KNQTVLEGNNVTLSCNASGIPAPVITWYRKDGSYM-PVNHRVV-----NGVLTVFNI 169

Query: 456 TLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489
           T +  G   C A+N  G    +  LN   K   V
Sbjct: 170 TKAHEGTYVCKAKNVLGAKTTEATLNCNNKGPTV 203



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 9/97 (9%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLPSGHRYRTVYDM 3884
            V  P   +   K+ TV E   V   C       P   I WYR +G  +P  HR   V  +
Sbjct: 108  VQVPVAILIPHKNQTVLEGNNVTLSCNASGIPAPV--ITWYRKDGSYMPVNHR--VVNGV 163

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISC 3921
                L +  +     G Y+C+A N  G   T+AT++C
Sbjct: 164  ----LTVFNITKAHEGTYVCKAKNVLGAKTTEATLNC 196



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 8/91 (8%)

Query: 2775 VFISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLD 2834
            + I H N  V  EG+N+   CN   S  P   I W+  +     G+     H      L 
Sbjct: 114  ILIPHKNQTVL-EGNNVTLSCNA--SGIPAPVITWYRKD-----GSYMPVNHRVVNGVLT 165

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRC 2865
            + +  +   G Y CKA N  G+ TT  +L C
Sbjct: 166  VFNITKAHEGTYVCKAKNVLGAKTTEATLNC 196



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 7/75 (9%)

Query: 79  KNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGP 138
           KN    +G N        G P PV++W RK           M  N +  +  L +  I  
Sbjct: 119 KNQTVLEGNNVTLSCNASGIPAPVITWYRKDGSY-------MPVNHRVVNGVLTVFNITK 171

Query: 139 GDEGEYTCTARNQYG 153
             EG Y C A+N  G
Sbjct: 172 AHEGTYVCKAKNVLG 186



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 17/50 (34%), Positives = 28/50 (56%)

Query: 1904 LDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            L I+   G D+G YTC+A N +G     + L VQ   +I+   ++++ LE
Sbjct: 76   LVIMEARGSDTGTYTCRARNMMGARDRHVVLRVQVPVAILIPHKNQTVLE 125



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 12/105 (11%)

Query: 1444 PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWF-KNGQPVTIGHRFRPIHDFGYV 1502
            P  +  P   + V+EG +V   C    +      + W+ K+G  + + HR   ++     
Sbjct: 111  PVAILIPHKNQTVLEGNNVTLSCNASGIPAP--VITWYRKDGSYMPVNHRV--VNG---- 162

Query: 1503 ALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS---TTDIVR 1544
             L + ++     G Y C+A N++G       L C +   T  IVR
Sbjct: 163  VLTVFNITKAHEGTYVCKAKNVLGAKTTEATLNCNNKGPTVTIVR 207



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 5/89 (5%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P  I    +N  + EG +       SG P P +TW++     +  N H ++    +  L 
Sbjct: 111 PVAILIPHKNQTVLEGNNVTLSCNASGIPAPVITWYRKDGSYMPVN-HRVV----NGVLT 165

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYL 353
           V N  K+  G Y   A+N  G   T   L
Sbjct: 166 VFNITKAHEGTYVCKAKNVLGAKTTEATL 194



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 28/113 (24%), Positives = 47/113 (41%), Gaps = 12/113 (10%)

Query: 632 RVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL-KNGQSIEASSRFTSIFR 690
           RV  P   ++P K+ T +EG  +         G P   I W  K+G  +  + R  +   
Sbjct: 107 RVQVPVAILIPHKNQTVLEGNNVTLSCNAS--GIPAPVITWYRKDGSYMPVNHRVVN--- 161

Query: 691 FGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVT---PRATIERTSQH 740
            G +++   ++     G Y C+A +  G   T+A L+     P  TI R   +
Sbjct: 162 -GVLTV--FNITKAHEGTYVCKAKNVLGAKTTEATLNCNNKGPTVTIVRVGTY 211



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 9/91 (9%)

Query: 1983 PIKNAEVTEGHPVHLEATLTPVNDPTMRVEWYC-NGRPVQQGHRFKTTYDFGYVALDILY 2041
            P KN  V EG+ V L    + +  P   + WY  +G  +   HR           L +  
Sbjct: 117  PHKNQTVLEGNNVTLSCNASGIPAPV--ITWYRKDGSYMPVNHRVVNG------VLTVFN 168

Query: 2042 AYAEDTGTYMCKATNAVGEAVTTSSVKVDAK 2072
                  GTY+CKA N +G   T +++  + K
Sbjct: 169  ITKAHEGTYVCKAKNVLGAKTTEATLNCNNK 199



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 2388 IQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEG 2447
            + EG      C     G P   + W+R     +D S +   H      +T+ ++    EG
Sbjct: 123  VLEGNNVTLSCNAS--GIPAPVITWYR-----KDGSYMPVNHRVVNGVLTVFNITKAHEG 175

Query: 2448 VYMCRASNLLG 2458
             Y+C+A N+LG
Sbjct: 176  TYVCKAKNVLG 186



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 17/50 (34%), Positives = 27/50 (54%)

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIE 1286
            L I+ A  +DTG YT RA N +G+     ++RV     I+   +N+  +E
Sbjct: 76   LVIMEARGSDTGTYTCRARNMMGARDRHVVLRVQVPVAILIPHKNQTVLE 125


>SB_39808| Best HMM Match : EGF_CA (HMM E-Value=6.3e-35)
          Length = 850

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 31/98 (31%), Positives = 42/98 (42%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P  II+  KD  + +G    F+CK  G P P + W  G     P              L 
Sbjct: 153  PTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLLPSGALV 212

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
            +      DEG Y+CVA N AG  T +A LKV   ++ +
Sbjct: 213  VKGVNLTDEGMYRCVASNPAGAATRSAVLKVQDLNECE 250



 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 8/95 (8%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSW---TRKKAPLVECNKYSMRYNEQTG 127
           P    Q  K+    QGG A F  K RG+P P ++W       APL   ++Y +     +G
Sbjct: 153 PTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLL---PSG 209

Query: 128 DVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
             +L++K +   DEG Y C A N  G A  S  ++
Sbjct: 210 --ALVVKGVNLTDEGMYRCVASNPAGAATRSAVLK 242



 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 262 PVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWF--KNGQR-LINSNKHEIITTH 318
           P  P  I Q P++  +++G  A F  +  G+P P + W    NG   L   ++++++ + 
Sbjct: 150 PYLPTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLLPS- 208

Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQ 364
               L V+    +D G Y  +A NP G    S  L V+   E  ++
Sbjct: 209 --GALVVKGVNLTDEGMYRCVASNPAGAATRSAVLKVQDLNECEIR 252



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 9/108 (8%)

Query: 380 EERIEISEKA-LAPQFV-KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFIN---DRQIRD 434
           E R++  E     P F+ +  +D  + +G    F+C+  G P P + W I    D  +  
Sbjct: 140 ESRLKYVENTPYLPTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPT 199

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV 482
           D  + +L   SG  AL++  V L+D G+  CVA N +G       L V
Sbjct: 200 DDRYDLL--PSG--ALVVKGVNLTDEGMYRCVASNPAGAATRSAVLKV 243



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%)

Query: 477 QCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQ--KDGVPIIPN 534
           + RL  +E    +    ++    + +R+G   V N +A G P P I W    +G   +P 
Sbjct: 140 ESRLKYVENTPYLPTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPT 199

Query: 535 PELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRA 576
            +       GA  L +     +D   Y+C A N AG+ ATR+
Sbjct: 200 DDRYDLLPSGA--LVVKGVNLTDEGMYRCVASNPAGA-ATRS 238



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 15/46 (32%), Positives = 22/46 (47%)

Query: 4104 ESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            E+    P   +  P  VT+ +G  A F C+  GHP P + W +  N
Sbjct: 147  ENTPYLPTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGAN 192



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 3689 DEKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWF--HNG-RPFATGSRVH 3745
            +  P  P F ++   ++ + +GG   F+C+    G P   I W    NG  P  T  R  
Sbjct: 147  ENTPYLPTFIIQTPKDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYD 204

Query: 3746 TLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTA 3783
             L      AL +  +   D G Y C A+N  G+AT +A
Sbjct: 205  LLPSG---ALVVKGVNLTDEGMYRCVASNPAGAATRSA 239



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 8/97 (8%)

Query: 3557 PPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWF--HNGK-PLLTGSRVKTINDFG 3613
            P     TP D+ + +  +A F C+       +  + W    NG  PL T  R   +    
Sbjct: 153  PTFIIQTPKDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYDLLPSGA 210

Query: 3614 FVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             V+    GV   D G+Y C A+N  G AT S  L+V+
Sbjct: 211  LVVK---GVNLTDEGMYRCVASNPAGAATRSAVLKVQ 244



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 1844 PRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV-LQSGHRYRTSNDFGFA 1902
            P FI Q      + +G +A + C+   +P P++      NG   L +  RY         
Sbjct: 153  PTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLLPS---G 209

Query: 1903 ALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            AL +  V   D G Y C A N  G A  S  L VQ
Sbjct: 210  ALVVKGVNLTDEGMYRCVASNPAGAATRSAVLKVQ 244



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 6/101 (5%)

Query: 630 EDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWL--KNGQSIEASSRFTS 687
           E+  Y P   I   K VT  +GG   F  +    G P   I W    NG +   +     
Sbjct: 147 ENTPYLPTFIIQTPKDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYD 204

Query: 688 IFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           +   G  +L +  +N+ D G Y C A +  G A   AVL V
Sbjct: 205 LLPSG--ALVVKGVNLTDEGMYRCVASNPAGAATRSAVLKV 243



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/93 (26%), Positives = 35/93 (37%), Gaps = 2/93 (2%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P F       ++I++GG A F  +    G     + W               +      A
Sbjct: 153  PTFIIQTPKDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYDLLPSGA 210

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            L +K V + D G Y C A N  G AT SA L +
Sbjct: 211  LVVKGVNLTDEGMYRCVASNPAGAATRSAVLKV 243



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQK-IRAGHRYRTTHDFGYV 2167
            P F+        +++G  A F C+      PH+      NG   +    RY        V
Sbjct: 153  PTFIIQTPKDVTIRQGGTAVFNCKARGHPAPHIAWAIGANGDAPLPTDDRYDLLPSGALV 212

Query: 2168 ALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
               +  T   D G Y C A+N  G A  +  LKV
Sbjct: 213  VKGVNLT---DEGMYRCVASNPAGAATRSAVLKV 243



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 8/86 (9%)

Query: 2782 NIVCKEGDNIHFECNVEPSRDPTLKIEWFFN---NKPLPSGTRYKSTHDFSYVSLDITHT 2838
            ++  ++G    F C       P   I W      + PLP+  RY      + V   +  T
Sbjct: 162  DVTIRQGGTAVFNCKARGH--PAPHIAWAIGANGDAPLPTDDRYDLLPSGALVVKGVNLT 219

Query: 2839 YEEDSGIYTCKATNSKGSATTSGSLR 2864
               D G+Y C A+N  G+AT S  L+
Sbjct: 220  ---DEGMYRCVASNPAGAATRSAVLK 242



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 8/89 (8%)

Query: 1718 KDIRVAENQAAHFEARLIPVGDPKLRVEWL--RNG-VPIEASNRLTTMHDFGYVALNMKY 1774
            KD+ + +   A F  +    G P   + W    NG  P+   +R   +      AL +K 
Sbjct: 161  KDVTIRQGGTAVFNCKAR--GHPAPHIAWAIGANGDAPLPTDDRYDLLPSG---ALVVKG 215

Query: 1775 VNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
            VN  D G Y C A N  G A  S+ L VQ
Sbjct: 216  VNLTDEGMYRCVASNPAGAATRSAVLKVQ 244


>SB_28651| Best HMM Match : ig (HMM E-Value=1.4e-09)
          Length = 221

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 36/120 (30%), Positives = 55/120 (45%), Gaps = 11/120 (9%)

Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNAR 513
           +VT S++G  TC A N+ G      ++ V  K ++V+      F    +     + L  +
Sbjct: 54  SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKI-----LSLQCK 108

Query: 514 AVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQNVAGS 571
           A G P+P+ITW K  G PI       +    G S L +   + A D   Y+C A N+ GS
Sbjct: 109 ARGVPSPQITWYKPGGQPITAG----VSPISGGSQLQVTTTREAGDYGQYKCRAFNLLGS 164



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 18/37 (48%), Positives = 25/37 (67%)

Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIV 3794
            D +   +AG YTC ATN+ GS TTT ++T + K +IV
Sbjct: 53   DSVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIV 89



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 14/118 (11%)

Query: 3116 TDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVP 3175
            +++GTY+C ATN+ G    +V++     +   KP   +   N     + +    +C    
Sbjct: 58   SEAGTYTCTATNEMGSDTTTVQV-----TVNYKPEIVSSTTN-TSFWNKKILSLQCKARG 111

Query: 3176 VDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQN-HDSGEYVCRAYNKYG 3231
            V  P  +I WY   GQP+  +  +  +S  G   L +  T+   D G+Y CRA+N  G
Sbjct: 112  VPSP--QITWYKPGGQPI--TAGVSPIS--GGSQLQVTTTREAGDYGQYKCRAFNLLG 163



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 16/39 (41%), Positives = 25/39 (64%)

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAES 1011
            SVT  +AG YTC A N +G  TT+  +T+  K +I++ +
Sbjct: 54   SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSST 92



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 2/85 (2%)

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            N  PEI+    +      + +   CK  G P P + WYK       +    +S  +    
Sbjct: 83   NYKPEIVSSTTNTSFWNKKILSLQCKARGVPSPQITWYKPGGQPITAGVSPISGGSQLQV 142

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRV 4704
                EA   D G YKC A+N  G V
Sbjct: 143  TTTREA--GDYGQYKCRAFNLLGSV 165



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRL-KKIQELEKYER--PKP-IE 2101
            + GTY C ATN +G   TT  V V+ K  +   T +     KKI  L+   R  P P I 
Sbjct: 59   EAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKILSLQCKARGVPSPQIT 118

Query: 2102 EEQPGQRPV 2110
              +PG +P+
Sbjct: 119  WYKPGGQPI 127



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 1476 LKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE-DSGIYTCRAVNLVGTDEVSCRL 1534
            LK+    +G P       R   +    ++   D +   ++G YTC A N +G+D  + ++
Sbjct: 21   LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEMGSDTTTVQV 80

Query: 1535 TCRSTTDIVRSTQN 1548
            T     +IV ST N
Sbjct: 81   TVNYKPEIVSSTTN 94



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY-EEDSGIYTCKATNSKGSATTS 2860
            LK+    +  P P+ T  +   + S  S+  + +    ++G YTC ATN  GS TT+
Sbjct: 21   LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEMGSDTTT 77



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 14/43 (32%), Positives = 25/43 (58%)

Query: 1374 SVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLILESQHPS 1416
            SV   ++G YTC ATN++G   T+  + V  K +++  + + S
Sbjct: 54   SVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTS 96



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 7/98 (7%)

Query: 1433 TDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK-NGQPVTIGH 1491
            T  +  +V  KP  V+   +  +    + +  +CK   V     ++ W+K  GQP+T G 
Sbjct: 75   TTTVQVTVNYKPEIVSSTTNT-SFWNKKILSLQCKARGVPSP--QITWYKPGGQPITAG- 130

Query: 1492 RFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDE 1529
               PI     + +      A D G Y CRA NL+G+ E
Sbjct: 131  -VSPISGGSQLQVTTTRE-AGDYGQYKCRAFNLLGSVE 166



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 9/120 (7%)

Query: 234 VSFRESITKRYVGESDVQISTEIDRSLGPVS-----PPKIAQKPRNSKLQEGADAQFQVQ 288
           V + +S+T+   G      + E+      V       P+I     N+          Q +
Sbjct: 49  VYYSDSVTRSEAGTYTCTATNEMGSDTTTVQVTVNYKPEIVSSTTNTSFWNKKILSLQCK 108

Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKS-DSGHYTLLAENPNGCI 347
             G P P++TW+K G + I +    I      + L+V  T+++ D G Y   A N  G +
Sbjct: 109 ARGVPSPQITWYKPGGQPITAGVSPI---SGGSQLQVTTTREAGDYGQYKCRAFNLLGSV 165


>SB_56353| Best HMM Match : I-set (HMM E-Value=6.3e-15)
          Length = 157

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 42/133 (31%), Positives = 57/133 (42%), Gaps = 12/133 (9%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNV---IEKEQVVAPKFVERFSTLNVREGE 506
           L I   T   +G+ TC   N+        +L V   IE +  + P+F      + V EGE
Sbjct: 31  LTIPYATRIHTGIYTCTGSNQYSYDQNSVQLRVAAPIEPQVSILPRF------MTVDEGE 84

Query: 507 PVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQ 566
            V     A G P+P I W   G P    P+  + +D     L IP+AK +    Y CTA+
Sbjct: 85  VVQFRCTASGFPSPVIQWL--GGPGGQLPKESVISDENR-VLTIPQAKKAHEGEYFCTAR 141

Query: 567 NVAGSTATRARLY 579
           N  G    R  LY
Sbjct: 142 NEGGVGTMRTMLY 154



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 4601 CVVSLPATKDKPKPQTK-AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKG 4659
            C  S   + D+   Q + AA   P++    +   V EG+ ++F C   G P P +QW  G
Sbjct: 46   CTGSNQYSYDQNSVQLRVAAPIEPQVSILPRFMTVDEGEVVQFRCTASGFPSPVIQWLGG 105

Query: 4660 DKLIKPSKYFQMSRTADE-YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                 P +    S  +DE   L I +A    EG+Y C A N  G  T+   L V
Sbjct: 106  PGGQLPKE----SVISDENRVLTIPQAKKAHEGEYFCTARNEGGVGTMRTMLYV 155



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 13/153 (8%)

Query: 4649 KPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAA 4708
            K   TV+W KG K   PS       T  +  L I  A     G Y C   N       + 
Sbjct: 5    KTYATVKWSKGLKGTLPS-----GATDKDGVLTIPYATRIHTGIYTCTGSNQYSYDQNSV 59

Query: 4709 KLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWL-REGALIPETPDF 4767
            +L+V  P +     ++ P R + V EG+  QF+   +    P IQWL   G  +P+    
Sbjct: 60   QLRVAAPIEPQ--VSILP-RFMTVDEGEVVQFRCTASGFPSPVIQWLGGPGGQLPK---- 112

Query: 4768 QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            + +    N VL I    +   G + C A    G
Sbjct: 113  ESVISDENRVLTIPQAKKAHEGEYFCTARNEGG 145



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 6/89 (6%)

Query: 258 RSLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKN-GQRLINSNKHEIIT 316
           R   P+ P +++  PR   + EG   QF+   SG P P + W    G +L    K  +I+
Sbjct: 62  RVAAPIEP-QVSILPRFMTVDEGEVVQFRCTASGFPSPVIQWLGGPGGQL---PKESVIS 117

Query: 317 THNHTTLRVRNTQKSDSGHYTLLAENPNG 345
             N   L +   +K+  G Y   A N  G
Sbjct: 118 DENR-VLTIPQAKKAHEGEYFCTARNEGG 145



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 15/128 (11%)

Query: 3107 VLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQK---PRFTTHIQNIEGLKD 3163
            VL I       +G Y+C  +N++   + SV+L      + Q    PRF T       + +
Sbjct: 30   VLTIPYATRIHTGIYTCTGSNQYSYDQNSVQLRVAAPIEPQVSILPRFMT-------VDE 82

Query: 3164 GQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
            G+   F CT      P   I+W   G P     +   +SD   V L I   +    GEY 
Sbjct: 83   GEVVQFRCTASGFPSP--VIQWL--GGPGGQLPKESVISDENRV-LTIPQAKKAHEGEYF 137

Query: 3224 CRAYNKYG 3231
            C A N+ G
Sbjct: 138  CTARNEGG 145



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 4116 LPDAVTVEEGEWARFCCRVTGHPKPRVMWL 4145
            LP  +TV+EGE  +F C  +G P P + WL
Sbjct: 74   LPRFMTVDEGEVVQFRCTASGFPSPVIQWL 103



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 8/85 (9%)

Query: 72  PIFEQIFKNARFA---QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGD 128
           PI  Q+    RF    +G   +F     G P+PV+ W     P  +  K S+  +E    
Sbjct: 66  PIEPQVSILPRFMTVDEGEVVQFRCTASGFPSPVIQWLG--GPGGQLPKESVISDENR-- 121

Query: 129 VSLLIKQIGPGDEGEYTCTARNQYG 153
             L I Q     EGEY CTARN+ G
Sbjct: 122 -VLTIPQAKKAHEGEYFCTARNEGG 145


>SB_24015| Best HMM Match : I-set (HMM E-Value=2.7e-21)
          Length = 609

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 31/196 (15%)

Query: 403 VTEGKMTRFDCRV-TGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVT-LSDS 460
           V E +     C V TG  Y   TW +N   +  D  H I  N  G   L I +V+ L D 
Sbjct: 65  VREWESVELYCNVNTGAVY---TWTVNGSAVVLDDLHTI--NPLGT--LQIASVSKLRDV 117

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTPT 519
           G   C+ARN +G  A    L +      V PKF      +   E G+PV+    A G P 
Sbjct: 118 GEYVCIARNAAGFGAASLELYI-----GVRPKFKTLPVPVEADEPGKPVLFKCSADGYPN 172

Query: 520 PRITWQKDGVPI----IPNPELRIHTDGG------------ASTLDIPRAKASDAAWYQC 563
           P I+W++DG+ I      N + ++  +G               +L I      D   Y C
Sbjct: 173 PTISWKRDGLLITSSSTSNSQYQVTNEGALLYHGKKHFITKEGSLIIFDPSEDDEGSYTC 232

Query: 564 TAQNVAGSTATRARLY 579
            A N  G    R  LY
Sbjct: 233 EAANEVGKAIHRITLY 248



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 24/188 (12%)

Query: 4630 KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED 4689
            K K+V E +++E  C +    + T  W      +       ++         +S+    D
Sbjct: 61   KKKLVREWESVELYCNVNTGAVYT--WTVNGSAVVLDDLHTINPLGTLQIASVSKL--RD 116

Query: 4690 EGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749
             G+Y C+A N+AG    + +L +    +   LP      +     G+P  FK        
Sbjct: 117  VGEYVCIARNAAGFGAASLELYIGVRPKFKTLPVPVEADE----PGKPVLFKCSADGYPN 172

Query: 4750 PTIQWLREGALIPET----PDFQMIHEG------------NNAVLLIGNTYEEDTGTFTC 4793
            PTI W R+G LI  +      +Q+ +EG                L+I +  E+D G++TC
Sbjct: 173  PTISWKRDGLLITSSSTSNSQYQVTNEGALLYHGKKHFITKEGSLIIFDPSEDDEGSYTC 232

Query: 4794 RATTAAGQ 4801
             A    G+
Sbjct: 233  EAANEVGK 240



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 46/173 (26%), Positives = 68/173 (39%), Gaps = 33/173 (19%)

Query: 4547 WLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP 4606
            W  NG  V  D  + I    GT  +  +    +D G+Y C+A N+AG      E  + + 
Sbjct: 85   WTVNGSAVVLDDLHTI-NPLGTLQIASVSKL-RDVGEYVCIARNAAGFGAASLELYIGV- 141

Query: 4607 ATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPS 4666
                  +P+ K    P E  EP        G+ + F C   G P PT+ W +   LI  S
Sbjct: 142  ------RPKFKTLPVPVEADEP--------GKPVLFKCSADGYPNPTISWKRDGLLITSS 187

Query: 4667 ----KYFQMSR------------TADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
                  +Q++                E +L I +   +DEG Y C A N  G+
Sbjct: 188  STSNSQYQVTNEGALLYHGKKHFITKEGSLIIFDPSEDDEGSYTCEAANEVGK 240



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 20/118 (16%)

Query: 1836 VEVAVNQAPRFITQLNGPTKLSE-GQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGH--- 1891
            +E+ +   P+F T L  P +  E G+   ++C  + YP+P   + W  +G ++ S     
Sbjct: 135  LELYIGVRPKFKT-LPVPVEADEPGKPVLFKCSADGYPNPT--ISWKRDGLLITSSSTSN 191

Query: 1892 -RYRTSNDFGF------------AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
             +Y+ +N+                +L I     +D G YTC+A N +G+A+  I L V
Sbjct: 192  SQYQVTNEGALLYHGKKHFITKEGSLIIFDPSEDDEGSYTCEAANEVGKAIHRITLYV 249



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 7/63 (11%)

Query: 4111 PVFVSLPDAVTVEE-GEWARFCCRVTGHPKPRVMW----LLNGNTIVNGSRYKLTYDG-- 4163
            P F +LP  V  +E G+   F C   G+P P + W    LL  ++  + S+Y++T +G  
Sbjct: 143  PKFKTLPVPVEADEPGKPVLFKCSADGYPNPTISWKRDGLLITSSSTSNSQYQVTNEGAL 202

Query: 4164 MYH 4166
            +YH
Sbjct: 203  LYH 205



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 13/25 (52%), Positives = 19/25 (76%)

Query: 1778 EDSGTYTCRAINELGEAVTSSTLFV 1802
            +D G+YTC A NE+G+A+   TL+V
Sbjct: 225  DDEGSYTCEAANEVGKAIHRITLYV 249



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 14/80 (17%)

Query: 91  FEGKLRGNPTPVVSWTRKKAPLVECNKYSMRY---NEQ-----------TGDVSLLIKQI 136
           F+    G P P +SW R    +   +  + +Y   NE            T + SL+I   
Sbjct: 163 FKCSADGYPNPTISWKRDGLLITSSSTSNSQYQVTNEGALLYHGKKHFITKEGSLIIFDP 222

Query: 137 GPGDEGEYTCTARNQYGEAI 156
              DEG YTC A N+ G+AI
Sbjct: 223 SEDDEGSYTCEAANEVGKAI 242



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 4/66 (6%)

Query: 1079 WYFNGKQITSANRIQTYHDFGYVALDIASV-RAEDSGVYTVVARNAAGEAQLSASMTVET 1137
            W  NG  +   + + T +  G   L IASV +  D G Y  +ARNAAG    S  + +  
Sbjct: 85   WTVNGSAVV-LDDLHTINPLG--TLQIASVSKLRDVGEYVCIARNAAGFGAASLELYIGV 141

Query: 1138 RSSIDT 1143
            R    T
Sbjct: 142  RPKFKT 147



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 6/71 (8%)

Query: 2951 GKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLI 3010
            G +L  G +  +T +   +   + D  E D G YTC+A N+ G+A    T+Y    D  +
Sbjct: 200  GALLYHGKKHFITKEGSLI---IFDPSEDDEGSYTCEAANEVGKAIHRITLYV---DITL 253

Query: 3011 ERTQHPKGTEG 3021
                H KG  G
Sbjct: 254  NTHAHYKGGGG 264



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 8/95 (8%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +P   T +P   ++ E  S    C    VN  ++   W  NG  ++    + TIN  G  
Sbjct: 52   DPVVVTVSPKKKLVREWESVELYCN---VNTGAVYT-WTVNGSAVVLDD-LHTINPLG-- 104

Query: 3616 ILEIGGVYQ-RDAGLYTCKATNRHGEATVSCKLQV 3649
             L+I  V + RD G Y C A N  G    S +L +
Sbjct: 105  TLQIASVSKLRDVGEYVCIARNAAGFGAASLELYI 139


>SB_52866| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1376

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 43/166 (25%), Positives = 67/166 (40%), Gaps = 17/166 (10%)

Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNE--SGNHALMITNVTLS 458
           R ++ GK     C ++G  +    W+    +I  D +    V+   SG + L + N+ ++
Sbjct: 230 RVISAGKNLVIKCTISGEQFQG--WYRGGSKIPTDSSQTKYVSNPTSGAYQLHLNNIVVA 287

Query: 459 DSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTP 518
           D G   C  R   G   FQ  ++            VE    L +   + + ++    G P
Sbjct: 288 DGGEYIC--RGNRGSKTFQLYVDFTTTH-------VELIQYLRISNADMIDIDV--YGYP 336

Query: 519 TPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            P   W K+G P  PN E R  T  G S +   R + SD   Y CT
Sbjct: 337 KPTFVWTKNGQPWNPN-EGRFSTQDGGS-VKFSRVEISDQGNYTCT 380



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 11/159 (6%)

Query: 4646 IVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC-VAYNSAGRV 4704
            + G P PT  W K  +   P++      T D  +++ S     D+G+Y C +A ++ G  
Sbjct: 332  VYGYPKPTFVWTKNGQPWNPNE--GRFSTQDGGSVKFSRVEISDQGNYTCTIAVDTLGLS 389

Query: 4705 TVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET 4764
            +V  K++V    +    P++ P+ D VV   + A           P ++W+R+G      
Sbjct: 390  SVK-KIEVITFVR----PSIKPMYDEVVEIDEQAYLDCVGEGNPLPEVRWIRDGRYERRQ 444

Query: 4765 PDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVE 4803
               Q+   G  + + I +   ED G +TC A   A   E
Sbjct: 445  ---QITLGGRRSRIYIQDVRLEDEGRYTCEARNNARDQE 480



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 42/182 (23%), Positives = 76/182 (41%), Gaps = 24/182 (13%)

Query: 4521 QNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580
            Q + +++  ++ +D  V G       W KNG+   P+      ++ G+     +E    D
Sbjct: 318  QYLRISNADMIDID--VYGYPKPTFVWTKNGQPWNPNEGRFSTQDGGSVKFSRVEI--SD 373

Query: 4581 SGKYEC-VAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
             G Y C +A+++ G +      V++        +P           I+P+ D++V   + 
Sbjct: 374  QGNYTCTIAVDTLGLSSVKKIEVITFV------RPS----------IKPMYDEVVEIDEQ 417

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
                C   G PLP V+W +  +  +  +     R +  Y   I +   EDEG Y C A N
Sbjct: 418  AYLDCVGEGNPLPEVRWIRDGRYERRQQITLGGRRSRIY---IQDVRLEDEGRYTCEARN 474

Query: 4700 SA 4701
            +A
Sbjct: 475  NA 476



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 6/78 (7%)

Query: 395 VKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LMIT 453
           +K   D  V   +    DC   G P PEV W  + R     Y  +  +   G  + + I 
Sbjct: 404 IKPMYDEVVEIDEQAYLDCVGEGNPLPEVRWIRDGR-----YERRQQITLGGRRSRIYIQ 458

Query: 454 NVTLSDSGVVTCVARNKS 471
           +V L D G  TC ARN +
Sbjct: 459 DVRLEDEGRYTCEARNNA 476



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 38/158 (24%), Positives = 58/158 (36%), Gaps = 10/158 (6%)

Query: 412 DCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKS 471
           D  V G P P   W  N +    +   +    + G+  +  + V +SD G  TC     +
Sbjct: 329 DIDVYGYPKPTFVWTKNGQPWNPNEG-RFSTQDGGS--VKFSRVEISDQGNYTCTI---A 382

Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            +T     +  IE    V P     +  + V   E   L+    G P P + W +DG   
Sbjct: 383 VDTLGLSSVKKIEVITFVRPSIKPMYDEV-VEIDEQAYLDCVGEGNPLPEVRWIRDG--- 438

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
                 +I   G  S + I   +  D   Y C A+N A
Sbjct: 439 RYERRQQITLGGRRSRIYIQDVRLEDEGRYTCEARNNA 476



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 7/87 (8%)

Query: 2369 EPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKT 2428
            E +T  RP        +  I E   A+ DC  +  G+P  +V W R+ +  E   +IT  
Sbjct: 395  EVITFVRPSIKPMYDEVVEIDE--QAYLDC--VGEGNPLPEVRWIRDGRY-ERRQQITLG 449

Query: 2429 HDFGYVSMTISHVRDEDEGVYMCRASN 2455
                 +   I  VR EDEG Y C A N
Sbjct: 450  GRRSRIY--IQDVRLEDEGRYTCEARN 474


>SB_8401| Best HMM Match : ig (HMM E-Value=8.1e-22)
          Length = 965

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 13/125 (10%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I +V   D+G    +  +  GET F+     ++   V+ P  V   + + V +    V
Sbjct: 675 LTIKDVQPQDAGEYAMILSDNGGETTFEASKFTLD---VLVPPSVTH-ANITVNKTNTAV 730

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L   A G PTP +TW + G         +    G   TL       SD   Y CTA N  
Sbjct: 731 LMCSATGNPTPNVTWTRSG---------KEDVLGTGETLTFSDVNISDGGCYVCTATNNI 781

Query: 570 GSTAT 574
           GS A+
Sbjct: 782 GSGAS 786



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 39/146 (26%), Positives = 62/146 (42%), Gaps = 20/146 (13%)

Query: 436 YNHKILVNESGNHALMITNVTLSDSGV--VTCVARNKSGETAFQC-RLNVIEKEQVVAPK 492
           Y   +L+ ++ N   M  N+ L   G+  +TCV  N +G    +   +NV EK   ++  
Sbjct: 807 YMDNLLIKKNING--MFHNILLDSVGIHLLTCVPINDAGVGENRSVSMNVTEKLPTIS-- 862

Query: 493 FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552
                +T+N  EG  VV    A+G  + +  W+KDGV             G  S+L +  
Sbjct: 863 ITPLRATVN--EGSVVVFTCLAIGFQSFKNFWKKDGV-----------FKGDGSSLMLSS 909

Query: 553 AKASDAAWYQCTAQNVAGSTATRARL 578
               D+  Y C   +  G+T   A L
Sbjct: 910 VGRDDSGNYTCNVTSTCGTTMKTASL 935



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 14/34 (41%), Positives = 22/34 (64%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +L ++S+  DDSG YTC  T+  G  + TAS+ +
Sbjct: 904  SLMLSSVGRDDSGNYTCNVTSTCGTTMKTASLDV 937



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 35/136 (25%), Positives = 54/136 (39%), Gaps = 20/136 (14%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L I+ V  +D+  +A +  + GG     A+    +        +VPPS  +T  N+ V  
Sbjct: 675  LTIKDVQPQDAGEYAMILSDNGGETTFEASKFTLDV-------LVPPS--VTHANITVNK 725

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGT-YTLLILEAYPQDSGKYEC 4586
                 L    TG    +V W ++GK+   D+        GT  TL   +    D G Y C
Sbjct: 726  TNTAVLMCSATGNPTPNVTWTRSGKE---DVL-------GTGETLTFSDVNISDGGCYVC 775

Query: 4587 VAINSAGEARCDAECV 4602
             A N+ G       C+
Sbjct: 776  TATNNIGSGASGTVCL 791



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 34/135 (25%), Positives = 50/135 (37%), Gaps = 13/135 (9%)

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+Y   + T +  TL I +  P+D G+Y  +  ++ G  T  A  K T        P++T
Sbjct: 661  SRYSLSTATFNPITLTIKDVQPQDAGEYAMILSDNGGETTFEAS-KFTLDVLVP--PSVT 717

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
               +I V +   A      T    P + W R G       D      G    L   +   
Sbjct: 718  H-ANITVNKTNTAVLMCSATGNPTPNVTWTRSG-----KEDVL----GTGETLTFSDVNI 767

Query: 4786 EDTGTFTCRATTAAG 4800
             D G + C AT   G
Sbjct: 768  SDGGCYVCTATNNIG 782



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 15/42 (35%), Positives = 21/42 (50%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTY 4161
            +TV +   A   C  TG+P P V W  +G   V G+   LT+
Sbjct: 721  ITVNKTNTAVLMCSATGNPTPNVTWTRSGKEDVLGTGETLTF 762


>SB_21597| Best HMM Match : ig (HMM E-Value=2.9e-14)
          Length = 1931

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 51/191 (26%), Positives = 70/191 (36%), Gaps = 20/191 (10%)

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRT 4674
            QT  A+AP     P      A G+ +  SC  V  P+P   W K D    P +       
Sbjct: 1390 QTYCASAPAITTHPQPLTETAAGKPLRLSCAAVATPMPAYYWVK-DGARLPGQ------- 1441

Query: 4675 ADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRD--IVV 4732
             +   L I E  PED G Y CVAYN      V +    +      ++P LT      + V
Sbjct: 1442 -NGSELIIIELKPEDNGTYICVAYNH-----VTSSKSASGHVIVHSVPVLTKQSSDHVTV 1495

Query: 4733 YEGQPAQFKTQITSKIKP-TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTF 4791
              G         T    P T QW R     P TP +  +      +L I +   +  G +
Sbjct: 1496 PVGGDVSLSVWATGTDLPLTYQWYRRD---PITPQYTPLSNEIYPMLTIHSARAQHQGGY 1552

Query: 4792 TCRATTAAGQV 4802
             C+ +   G V
Sbjct: 1553 RCQVSNRYGDV 1563



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 51/194 (26%), Positives = 83/194 (42%), Gaps = 30/194 (15%)

Query: 4514 PSFTLTAQNVNVTS-GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            P+ T   Q +  T+ G+ +RL      T     YW+K+G ++          ++G+  L+
Sbjct: 1397 PAITTHPQPLTETAAGKPLRLSCAAVATPMPAYYWVKDGARLPG--------QNGS-ELI 1447

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
            I+E  P+D+G Y CVA N    ++  +  V+                ++ P + +   D 
Sbjct: 1448 IIELKPEDNGTYICVAYNHVTSSKSASGHVI---------------VHSVPVLTKQSSDH 1492

Query: 4633 I-VAEGQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
            + V  G  +  S    G  LP T QWY+ D  I P +Y  +S       L I  A  + +
Sbjct: 1493 VTVPVGGDVSLSVWATGTDLPLTYQWYRRDP-ITP-QYTPLSNEIYP-MLTIHSARAQHQ 1549

Query: 4691 GDYKCVAYNSAGRV 4704
            G Y+C   N  G V
Sbjct: 1550 GGYRCQVSNRYGDV 1563



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%)

Query: 1620 LKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVT-SGIAIVHSKKSIYLE 1678
            +K G+R    N    + +++    PED+GTY C A N +  + + SG  IVHS   +  +
Sbjct: 1432 VKDGARLPGQNGSELIIIELK---PEDNGTYICVAYNHVTSSKSASGHVIVHSVPVLTKQ 1488

Query: 1679 SQHEGALP 1686
            S     +P
Sbjct: 1489 SSDHVTVP 1496


>SB_52846| Best HMM Match : ig (HMM E-Value=9e-12)
          Length = 330

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 54/240 (22%), Positives = 97/240 (40%), Gaps = 15/240 (6%)

Query: 4578 PQD-SGKYECVAINSAGEARCDAECVVSLPATKDKPK-PQTKAANAPPEIIEPL-KDKIV 4634
            P+D SG+   ++  S  +     +C+V     K + +  Q K    P  I++P  K  I 
Sbjct: 33   PEDKSGRNLIISQVSKEQHEGVYQCIVENNQGKTESQLSQLKVFVPPGWIVKPPPKMNIP 92

Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694
              G A+   C+  G P P   WY     I  S++  +  T ++ T +  E + E  G Y+
Sbjct: 93   MYGGAV-LLCEAFGDPTPAYGWYVNGSKIVNSQHLIV--TNNKLTFKAVELY-EHAGIYQ 148

Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
            CVA N  G V     +++         P +       +++    + K    +       W
Sbjct: 149  CVAENDYGMVVSTTVVEIDA-----RKPGIIGFGPFYIFKDTKGEIKCDSNAAPAANHVW 203

Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             ++  ++  +  + +   GN+  L+I    + D G +TC+AT   G    S    V  +T
Sbjct: 204  SKDDQVLSISGRYSL-GPGNS--LVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYERT 260



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 34/131 (25%), Positives = 58/131 (44%), Gaps = 9/131 (6%)

Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870
            + QHE   Q I +        +   ++V V   P +I +   P K++           E 
Sbjct: 48   KEQHEGVYQCIVENNQGKTESQLSQLKVFV--PPGWIVK--PPPKMNIPMYGGAVLLCEA 103

Query: 1871 YPDPNMRVEWYFNG-KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929
            + DP     WY NG K++ S H   T+N   F A+++     E +G Y C A N+ G  V
Sbjct: 104  FGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVELY----EHAGIYQCVAENDYGMVV 159

Query: 1930 SSIRLNVQSKE 1940
            S+  + + +++
Sbjct: 160  STTVVEIDARK 170



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           V P  I + P    +     A    +  G+P P   W+ NG +++NS    +I T+N  T
Sbjct: 77  VPPGWIVKPPPKMNIPMYGGAVLLCEAFGDPTPAYGWYVNGSKIVNS--QHLIVTNNKLT 134

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            +     +  +G Y  +AEN  G +V++  + +++
Sbjct: 135 FKAVELYE-HAGIYQCVAENDYGMVVSTTVVEIDA 168



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 5/68 (7%)

Query: 2006 DPTMRVEWYCNG-RPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            DPT    WY NG + V   H   T     + A++ LY +A   G Y C A N  G  V+T
Sbjct: 106  DPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVE-LYEHA---GIYQCVAENDYGMVVST 161

Query: 2065 SSVKVDAK 2072
            + V++DA+
Sbjct: 162  TVVEIDAR 169



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 7/99 (7%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGF 3752
            PP + V+    +++P  G     C  E  GDPT    W+ NG         + T N   F
Sbjct: 78   PPGWIVKPPPKMNIPMYGGAVLLC--EAFGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTF 135

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791
             A+++       AG Y C A N +G   +T  +   A++
Sbjct: 136  KAVEL----YEHAGIYQCVAENDYGMVVSTTVVEIDARK 170



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 39/147 (26%), Positives = 61/147 (41%), Gaps = 12/147 (8%)

Query: 428 NDR-QIRDDYNHKILVNESGNHALMITNVTLSD-SGVVTCVARNKSGETAFQCRLNVIEK 485
           ND+  I D  N   +  +     L+I+ V+     GV  C+  N  G+T  Q     + +
Sbjct: 18  NDKLPIVDGKNGFSIPEDKSGRNLIISQVSKEQHEGVYQCIVENNQGKTESQ-----LSQ 72

Query: 486 EQVVAPK--FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG 543
            +V  P    V+    +N+      VL   A G PTP   W  +G  I+ N +  I T+ 
Sbjct: 73  LKVFVPPGWIVKPPPKMNIPMYGGAVLLCEAFGDPTPAYGWYVNGSKIV-NSQHLIVTNN 131

Query: 544 GASTLDIPRAKASDAAWYQCTAQNVAG 570
             +   +   +   A  YQC A+N  G
Sbjct: 132 KLTFKAVELYE--HAGIYQCVAENDYG 156



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 2134 EPINDPHLTIDWFHNGQKI-RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE 2192
            E   DP     W+ NG KI  + H   T +   + A++ LY +A   G Y C A N  G 
Sbjct: 102  EAFGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVE-LYEHA---GIYQCVAENDYGM 157

Query: 2193 AVNTCTLKV 2201
             V+T  +++
Sbjct: 158  VVSTTVVEI 166



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 5/74 (6%)

Query: 1338 GDQTMRVEWFCNG-KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
            GD T    W+ NG K + + H      +  + A++L     E +G+Y C A N  G  V+
Sbjct: 105  GDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVELY----EHAGIYQCVAENDYGMVVS 160

Query: 1397 SCALRVIAKKDLIL 1410
            +  + + A+K  I+
Sbjct: 161  TTVVEIDARKPGII 174



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 15/37 (40%), Positives = 22/37 (59%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            +L I  ++ +D G YTCKATNLLG    +    + +R
Sbjct: 223  SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 259



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 6/114 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            TE  L  +    PP ++ +   + ++         C+    GDP     W+ NG  +++ 
Sbjct: 66   TESQLSQLKVFVPPGWIVKPPPKMNIPMYGGAVLLCEA--FGDPTPAYGWYVNGSKIVNS 123

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG-KPGIV 4072
                 I     +      +Y E +G Y C A N YGM  +  V++    KPGI+
Sbjct: 124  QHL--IVTNNKLTFKAVELY-EHAGIYQCVAENDYGMVVSTTVVEIDARKPGII 174



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            W KD + +  S R +     G  +L I  V  +D G YTC+A N +G  T S + T+  +
Sbjct: 203  WSKDDQVLSISGRYS--LGPGN-SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 259

Query: 1005 KDI 1007
              I
Sbjct: 260  TKI 262



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/66 (34%), Positives = 27/66 (40%)

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V Q D G YTCKATN  G  T S    V  R  I + P        G  +  + +
Sbjct: 224  LVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYERTKITVRPDASVELIKGKPTDFRCQ 283

Query: 3677 ETLHKR 3682
             T   R
Sbjct: 284  ATADPR 289



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W K+ Q ++I  R+        V   I  +   D G YTC+A NL+GTD  S   T    
Sbjct: 203  WSKDDQVLSISGRYSLGPGNSLV---ITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 259

Query: 1540 TDIVRSTQNEAGLEQIQ 1556
            T I  + + +A +E I+
Sbjct: 260  TKI--TVRPDASVELIK 274



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 16/29 (55%), Positives = 18/29 (62%)

Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSATTS 2860
            SL IT   + D G YTCKATN  G+ T S
Sbjct: 223  SLVITPVQQNDEGKYTCKATNLLGTDTKS 251



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 8/102 (7%)

Query: 632 RVYPPPQFIV--PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
           +V+ PP +IV  P K    M GG +      E  GDPT    W  NG  I  S     I 
Sbjct: 74  KVFVPPGWIVKPPPKMNIPMYGGAVLL---CEAFGDPTPAYGWYVNGSKIVNSQHL--IV 128

Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
               ++   + L  + +G Y C A +  G+  +  V+ +  R
Sbjct: 129 TNNKLTFKAVEL-YEHAGIYQCVAENDYGMVVSTTVVEIDAR 169



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 13/24 (54%), Positives = 18/24 (75%)

Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458
            S+ I+ V+  DEG Y C+A+NLLG
Sbjct: 223  SLVITPVQQNDEGKYTCKATNLLG 246



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 36/160 (22%), Positives = 61/160 (38%), Gaps = 14/160 (8%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD-SGVVTCVARNKS 471
           C   G P P   W++N  +I +   H I+     N+ L    V L + +G+  CVA N  
Sbjct: 101 CEAFGDPTPAYGWYVNGSKIVNS-QHLIVT----NNKLTFKAVELYEHAGIYQCVAENDY 155

Query: 472 GETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
           G         V+E +    P  +  F    + +     +   +   P     W KD   +
Sbjct: 156 GMVV---STTVVEID-ARKPGII-GFGPFYIFKDTKGEIKCDSNAAPAANHVWSKDDQVL 210

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGS 571
             +    +   G  ++L I   + +D   Y C A N+ G+
Sbjct: 211 SISGRYSL---GPGNSLVITPVQQNDEGKYTCKATNLLGT 247


>SB_12096| Best HMM Match : ig (HMM E-Value=9.4e-33)
          Length = 942

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 54/240 (22%), Positives = 97/240 (40%), Gaps = 15/240 (6%)

Query: 4578 PQD-SGKYECVAINSAGEARCDAECVVSLPATKDKPK-PQTKAANAPPEIIEPL-KDKIV 4634
            P+D SG+   ++  S  +     +C+V     K + +  Q K    P  I++P  K  I 
Sbjct: 617  PEDKSGRNLIISQVSKEQHEGVYQCIVENNQGKTESQLSQLKVFVPPGWIVKPPPKMNIP 676

Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694
              G A+   C+  G P P   WY     I  S++  +  T ++ T +  E + E  G Y+
Sbjct: 677  MYGGAV-LLCEAFGDPTPAYGWYVNGSKIVNSQHLIV--TNNKLTFKAVELY-EHAGIYQ 732

Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
            CVA N  G V     +++         P +       +++    + K    +       W
Sbjct: 733  CVAENDYGMVVSTTVVEIDA-----RKPGIIGFGPFYIFKDTKGEIKCDSNAAPAANHVW 787

Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
             ++  ++  +  + +   GN+  L+I    + D G +TC+AT   G    S    V  +T
Sbjct: 788  SKDDQVLSISGRYSL-GPGNS--LVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYERT 844



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 34/131 (25%), Positives = 58/131 (44%), Gaps = 9/131 (6%)

Query: 1811 ESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEP 1870
            + QHE   Q I +        +   ++V V   P +I +   P K++           E 
Sbjct: 632  KEQHEGVYQCIVENNQGKTESQLSQLKVFV--PPGWIVK--PPPKMNIPMYGGAVLLCEA 687

Query: 1871 YPDPNMRVEWYFNG-KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAV 1929
            + DP     WY NG K++ S H   T+N   F A+++     E +G Y C A N+ G  V
Sbjct: 688  FGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVELY----EHAGIYQCVAENDYGMVV 743

Query: 1930 SSIRLNVQSKE 1940
            S+  + + +++
Sbjct: 744  STTVVEIDARK 754



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           V P  I + P    +     A    +  G+P P   W+ NG +++NS    +I T+N  T
Sbjct: 661 VPPGWIVKPPPKMNIPMYGGAVLLCEAFGDPTPAYGWYVNGSKIVNS--QHLIVTNNKLT 718

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            +     +  +G Y  +AEN  G +V++  + +++
Sbjct: 719 FKAVELYE-HAGIYQCVAENDYGMVVSTTVVEIDA 752



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 67/266 (25%), Positives = 105/266 (39%), Gaps = 35/266 (13%)

Query: 4436 GEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILIIRQV-FVEDSAVFAAVAENRGGTAKC 4494
            G+P P   WY     I NS     H   T + L  + V   E + ++  VAEN  G    
Sbjct: 689  GDPTPAYGWYVNGSKIVNSQ----HLIVTNNKLTFKAVELYEHAGIYQCVAENDYGMV-V 743

Query: 4495 SANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKV 4554
            S  +V  + R+ G  G  P  F +       T G+ ++ D+        +  W K+ + +
Sbjct: 744  STTVVEIDARKPGIIGFGP--FYIFKD----TKGE-IKCDSNAAPAA--NHVWSKDDQVL 794

Query: 4555 QPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKP 4614
               I  +     G  +L+I      D GKY C A N  G      +  V           
Sbjct: 795  S--ISGRYSLGPGN-SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVY---------E 842

Query: 4615 QTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKP-LPTVQWYKGDKLIKPSKYFQ-MS 4672
            +TK    P   +E +K      G+  +F C+    P L  +  YK  K     +Y + ++
Sbjct: 843  RTKITVRPDASVELIK------GKPTDFRCQATADPRLMNILKYKWLKDGTELQYTENIN 896

Query: 4673 RTADEYTLRISEAFPEDEGDYKCVAY 4698
               ++  L++SEA  +D   Y CVAY
Sbjct: 897  WIPNQLRLKLSEADIDDGAVYTCVAY 922



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 5/68 (7%)

Query: 2006 DPTMRVEWYCNG-RPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            DPT    WY NG + V   H   T     + A++ LY +A   G Y C A N  G  V+T
Sbjct: 690  DPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVE-LYEHA---GIYQCVAENDYGMVVST 745

Query: 2065 SSVKVDAK 2072
            + V++DA+
Sbjct: 746  TVVEIDAR 753



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 7/99 (7%)

Query: 3694 PPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR-VHTLNDFGF 3752
            PP + V+    +++P  G     C  E  GDPT    W+ NG         + T N   F
Sbjct: 662  PPGWIVKPPPKMNIPMYGGAVLLC--EAFGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTF 719

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKR 3791
             A+++       AG Y C A N +G   +T  +   A++
Sbjct: 720  KAVEL----YEHAGIYQCVAENDYGMVVSTTVVEIDARK 754



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 20/66 (30%), Positives = 39/66 (59%), Gaps = 4/66 (6%)

Query: 4533 LDTKVTGTKPIDVYWLKNGKKV-QPDIRNKIL--EEDGTYTLLILEAYP-QDSGKYECVA 4588
            L+ + +G  PI +YW K+GK + + + + +I+  ++ G   L +    P QD+G ++C A
Sbjct: 354  LECRASGKTPITMYWEKDGKLLAELEFKYEIITDKQKGVSKLKVQIPRPSQDNGNFQCFA 413

Query: 4589 INSAGE 4594
             N+ G+
Sbjct: 414  ENAEGK 419



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 51/213 (23%), Positives = 83/213 (38%), Gaps = 22/213 (10%)

Query: 372 TDTQQRETEERIEISEKALAPQFVKVCQDRDVT---EGKMTRFDCRVTGRPYPE--VTWF 426
           T T  +   +++      L P FV+  + + +    +GK     C     P P   + W 
Sbjct: 536 TYTSHKFLLKQVGTDNSPLKPVFVQDGEPKTLESAIQGKSKALFCVAQMSPAPNNAIRWV 595

Query: 427 -----INDR-QIRDDYNHKILVNESGNHALMITNVTLSD-SGVVTCVARNKSGETAFQCR 479
                 ND+  I D  N   +  +     L+I+ V+     GV  C+  N  G+T  Q  
Sbjct: 596 RVDSVTNDKLPIVDGKNGFSIPEDKSGRNLIISQVSKEQHEGVYQCIVENNQGKTESQ-- 653

Query: 480 LNVIEKEQVVAPK--FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
              + + +V  P    V+    +N+      VL   A G PTP   W  +G  I+ N + 
Sbjct: 654 ---LSQLKVFVPPGWIVKPPPKMNIPMYGGAVLLCEAFGDPTPAYGWYVNGSKIV-NSQH 709

Query: 538 RIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
            I T+   +   +   +   A  YQC A+N  G
Sbjct: 710 LIVTNNKLTFKAVELYE--HAGIYQCVAENDYG 740



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 2134 EPINDPHLTIDWFHNGQKI-RAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGE 2192
            E   DP     W+ NG KI  + H   T +   + A++ LY +A   G Y C A N  G 
Sbjct: 686  EAFGDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVE-LYEHA---GIYQCVAENDYGM 741

Query: 2193 AVNTCTLKV 2201
             V+T  +++
Sbjct: 742  VVSTTVVEI 750



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 5/74 (6%)

Query: 1338 GDQTMRVEWFCNG-KPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVT 1396
            GD T    W+ NG K + + H      +  + A++L     E +G+Y C A N  G  V+
Sbjct: 689  GDPTPAYGWYVNGSKIVNSQHLIVTNNKLTFKAVELY----EHAGIYQCVAENDYGMVVS 744

Query: 1397 SCALRVIAKKDLIL 1410
            +  + + A+K  I+
Sbjct: 745  TTVVEIDARKPGII 758



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 15/37 (40%), Positives = 22/37 (59%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDR 2737
            +L I  ++ +D G YTCKATNLLG    +    + +R
Sbjct: 807  SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 843



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 33/139 (23%), Positives = 55/139 (39%), Gaps = 13/139 (9%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   +  D G Y+C+ATN  G        +  D +  ++ + T        L  G+  
Sbjct: 808  LVITPVQQNDEGKYTCKATNLLG-----TDTKSNDATVYERTKITVRPDASVELIKGKPT 862

Query: 3168 HFEC--TVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCR 3225
             F C  T  P     +K +W  +G  ++++  I  + +   + L ++     D   Y C 
Sbjct: 863  DFRCQATADPRLMNILKYKWLKDGTELQYTENINWIPN--QLRLKLSEADIDDGAVYTCV 920

Query: 3226 AYN----KYGEDFTRATIN 3240
            AY     KY ED   +  N
Sbjct: 921  AYTDDKLKYSEDRASSIAN 939



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 6/114 (5%)

Query: 3960 TEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHK 4019
            TE  L  +    PP ++ +   + ++         C+    GDP     W+ NG  +++ 
Sbjct: 650  TESQLSQLKVFVPPGWIVKPPPKMNIPMYGGAVLLCEA--FGDPTPAYGWYVNGSKIVNS 707

Query: 4020 NRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVIKTTG-KPGIV 4072
                 I     +      +Y E +G Y C A N YGM  +  V++    KPGI+
Sbjct: 708  QHL--IVTNNKLTFKAVELY-EHAGIYQCVAENDYGMVVSTTVVEIDARKPGII 758



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 945  WLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTK 1004
            W KD + +  S R +     G  +L I  V  +D G YTC+A N +G  T S + T+  +
Sbjct: 787  WSKDDQVLSISGRYS--LGPGN-SLVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 843

Query: 1005 KDI 1007
              I
Sbjct: 844  TKI 846



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/66 (34%), Positives = 27/66 (40%)

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTESIQKLE 3676
            L I  V Q D G YTCKATN  G  T S    V  R  I + P        G  +  + +
Sbjct: 808  LVITPVQQNDEGKYTCKATNLLGTDTKSNDATVYERTKITVRPDASVELIKGKPTDFRCQ 867

Query: 3677 ETLHKR 3682
             T   R
Sbjct: 868  ATADPR 873



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 4/87 (4%)

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECK--LEPVTDSNLKVEWFKNGQPVTIGHRFR 1494
            D +V  + +   RP +   +I+G+   F C+   +P   + LK +W K+G  +       
Sbjct: 837  DATVYERTKITVRPDASVELIKGKPTDFRCQATADPRLMNILKYKWLKDGTELQYTENIN 896

Query: 1495 PIHDFGYVALDIIDLIAEDSGIYTCRA 1521
             I +   + L + +   +D  +YTC A
Sbjct: 897  WIPN--QLRLKLSEADIDDGAVYTCVA 921



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRST 1539
            W K+ Q ++I  R+        V   I  +   D G YTC+A NL+GTD  S   T    
Sbjct: 787  WSKDDQVLSISGRYSLGPGNSLV---ITPVQQNDEGKYTCKATNLLGTDTKSNDATVYER 843

Query: 1540 TDIVRSTQNEAGLEQIQ 1556
            T I  + + +A +E I+
Sbjct: 844  TKI--TVRPDASVELIK 858



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 16/29 (55%), Positives = 18/29 (62%)

Query: 2832 SLDITHTYEEDSGIYTCKATNSKGSATTS 2860
            SL IT   + D G YTCKATN  G+ T S
Sbjct: 807  SLVITPVQQNDEGKYTCKATNLLGTDTKS 835



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 8/102 (7%)

Query: 632 RVYPPPQFIV--PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIF 689
           +V+ PP +IV  P K    M GG +      E  GDPT    W  NG  I  S     I 
Sbjct: 658 KVFVPPGWIVKPPPKMNIPMYGGAVLL---CEAFGDPTPAYGWYVNGSKIVNSQHL--IV 712

Query: 690 RFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPR 731
               ++   + L  + +G Y C A +  G+  +  V+ +  R
Sbjct: 713 TNNKLTFKAVEL-YEHAGIYQCVAENDYGMVVSTTVVEIDAR 753



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 13/24 (54%), Positives = 18/24 (75%)

Query: 2435 SMTISHVRDEDEGVYMCRASNLLG 2458
            S+ I+ V+  DEG Y C+A+NLLG
Sbjct: 807  SLVITPVQQNDEGKYTCKATNLLG 830


>SB_26137| Best HMM Match : Plasmodium_HRP (HMM E-Value=0.27)
          Length = 271

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 35/182 (19%), Positives = 82/182 (45%), Gaps = 5/182 (2%)

Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279
            +T +  +TE E E+  E+    +++   +   + + +  +E E E ++  +R+K  E   
Sbjct: 77   QTEKEAQTEKEAER--EKEAETEKEAQTEKEAQTEKEAEREKEAETEKEAEREKEAEREI 134

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339
            + +  +  +  KE++  +        G +  + T  ++  ++  +   + +   E + +K
Sbjct: 135  EAETEKEAETEKEAQTEKEAQTEKEAGTEKEAQTEKEAQMEKEAETEKEAQTEKEAQTEK 194

Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITR-KITSTE-TTEIEHKAQTQ 4397
            +  ++       E+    KE    K+ QT+KE    KE  + K   TE   E E +A+T+
Sbjct: 195  EAEREKEAETEKEAKTE-KEAETEKEAQTEKEAETQKEAEKQKEAETEKEAETEKEAETE 253

Query: 4398 ER 4399
            ++
Sbjct: 254  KK 255



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 37/179 (20%), Positives = 70/179 (39%), Gaps = 3/179 (1%)

Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279
            E  + +  ETE E   E+    +++   +   E + +  +E E E +   + +K  E   
Sbjct: 87   EAEREKEAETEKEAQTEKEAQTEKEAEREKEAETEKEAEREKEAEREIEAETEKEAETEK 146

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339
            + Q  +  Q  KE+   +          +  + T  ++  ++      + E   E   +K
Sbjct: 147  EAQTEKEAQTEKEAGTEKEAQTEKEAQMEKEAETEKEAQTEKEAQTEKEAEREKEAETEK 206

Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEI-TRKITSTET-TEIEHKAQT 4396
            +   +       E+    KE    K+ + QKE   +KE  T K   TE   E E +A+T
Sbjct: 207  EAKTEKEAETEKEAQTE-KEAETQKEAEKQKEAETEKEAETEKEAETEKKAETEKEAET 264



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 4305 PGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAK 4364
            PG++V+ N   + M    E   ++  +  ++  ++K  +  +     +     KE    K
Sbjct: 58   PGNQVSRNG-REGMGTEKEAQTEKEAQTEKEAEREKEAETEKEAQTEKEAQTEKEAEREK 116

Query: 4365 QKQTQKEVVGDKEITRKI-TSTE-TTEIEHKAQTQE 4398
            + +T+KE   +KE  R+I   TE   E E +AQT++
Sbjct: 117  EAETEKEAEREKEAEREIEAETEKEAETEKEAQTEK 152


>SB_2034| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1003

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 9/118 (7%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L+I N+  SD     C+A+N  GE + +  +  I ++ V+     +    +    G+   
Sbjct: 122 LVIKNLQTSDVASYKCLAKNNIGEISAEVEVTRISEQAVITSDIKDATKVV----GDAFE 177

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           +   A G     + W+++G P +   +       G S + I   K SDAA + CTA N
Sbjct: 178 VACEATGASPLSVEWKRNGSPYLGQEK-----SNGKSVIKIQSLKLSDAAQFTCTASN 230



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 58/249 (23%), Positives = 90/249 (36%), Gaps = 39/249 (15%)

Query: 4560 NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +K +  DG   L+I      D   Y+C+A N+ GE   + E                   
Sbjct: 113  SKYVMNDGC--LVIKNLQTSDVASYKCLAKNNIGEISAEVEVT---------------RI 155

Query: 4620 NAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYT 4679
            +    I   +KD     G A E +C+  G    +V+W +       S Y    ++  +  
Sbjct: 156  SEQAVITSDIKDATKVVGDAFEVACEATGASPLSVEWKRNG-----SPYLGQEKSNGKSV 210

Query: 4680 LRISEAFPEDEGDYKCVAYNSA---GRVTVAA---KLKVTQPDQADNLPALTPLRDIVVY 4733
            ++I      D   + C A N     G+  V+    KL V  P       + TPL    V 
Sbjct: 211  IKIQSLKLSDAAQFTCTASNGLQFNGKDVVSTKSFKLTVEAPPTVVLEGSKTPLHSF-VG 269

Query: 4734 EGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIGNTYEEDTGTFT 4792
               P   K Q T    PT+   ++G         + + +GN  A L +  +   D GTF 
Sbjct: 270  NTIPVTIKCQFTGLPMPTVVMTKDG---------KEVAKGNGTAQLDVVTSVTSDFGTFI 320

Query: 4793 CRATTAAGQ 4801
            C A    G+
Sbjct: 321  CEANNKRGR 329



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 52/248 (20%), Positives = 87/248 (35%), Gaps = 28/248 (11%)

Query: 4468 LIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTS 4527
            L+I+ +   D A +  +A+N  G  + SA + V     Q          T   ++     
Sbjct: 122  LVIKNLQTSDVASYKCLAKNNIG--EISAEVEVTRISEQA-------VITSDIKDATKVV 172

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECV 4587
            G    +  + TG  P+ V W +NG    P +  +  + +G   + I      D+ ++ C 
Sbjct: 173  GDAFEVACEATGASPLSVEWKRNG---SPYLGQE--KSNGKSVIKIQSLKLSDAAQFTCT 227

Query: 4588 AINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIV 4647
            A N       D     S   T + P       +  P          V     +   C+  
Sbjct: 228  ASNGLQFNGKDVVSTKSFKLTVEAPPTVVLEGSKTP------LHSFVGNTIPVTIKCQFT 281

Query: 4648 GKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVA 4707
            G P+PTV   K  K        ++++      L +  +   D G + C A N  GR    
Sbjct: 282  GLPMPTVVMTKDGK--------EVAKGNGTAQLDVVTSVTSDFGTFICEANNKRGRKLNN 333

Query: 4708 AKLKVTQP 4715
              LK+  P
Sbjct: 334  IMLKMAVP 341



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 55/235 (23%), Positives = 82/235 (34%), Gaps = 23/235 (9%)

Query: 342 NPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERI-EISEKALAPQFVKVCQD 400
           NP+  ++  G L +++   S V   +     +  +   E  +  ISE+A+    +K   D
Sbjct: 111 NPSKYVMNDGCLVIKNLQTSDVASYKCLAKNNIGEISAEVEVTRISEQAVITSDIK---D 167

Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
                G      C  TG     V W  N                +G   + I ++ LSD+
Sbjct: 168 ATKVVGDAFEVACEATGASPLSVEWKRNGSPYLGQEK------SNGKSVIKIQSLKLSDA 221

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV--ERFST-LNVREGE--PVVLNARAV 515
              TC A N               K  V AP  V  E   T L+   G   PV +  +  
Sbjct: 222 AQFTCTASNGLQFNGKDVVSTKSFKLTVEAPPTVVLEGSKTPLHSFVGNTIPVTIKCQFT 281

Query: 516 GTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           G P P +   KDG  +            G + LD+  +  SD   + C A N  G
Sbjct: 282 GLPMPTVVMTKDGKEVAKG--------NGTAQLDVVTSVTSDFGTFICEANNKRG 328



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 71/319 (22%), Positives = 127/319 (39%), Gaps = 31/319 (9%)

Query: 3715 FDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATN 3774
            F+   E  G   + ++W  NG P+    + +     G   + I  +   DA ++TC A+N
Sbjct: 176  FEVACEATGASPLSVEWKRNGSPYLGQEKSN-----GKSVIKIQSLKLSDAAQFTCTASN 230

Query: 3775 ------KWGSATTTAKITCSAKRDIVLE-SQLP-QGMSGEKIKELERGRISDAPKEEPIV 3826
                  K   +T + K+T  A   +VLE S+ P     G  I    + + +  P    ++
Sbjct: 231  GLQFNGKDVVSTKSFKLTVEAPPTVVLEGSKTPLHSFVGNTIPVTIKCQFTGLPMPTVVM 290

Query: 3827 STPPKFI------TQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRT 3880
            +   K +       Q+   T   S+   F C    K   KL     +    +P G     
Sbjct: 291  TKDGKEVAKGNGTAQLDVVTSVTSDFGTFICEANNKRGRKLNNIMLK--MAVPPGKPLDV 348

Query: 3881 VYDMGFVSLDILYVY-AEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRGMKR 3939
              +    ++ + + + A D G YI   +   G    +ATI  KK     L+++  R  K 
Sbjct: 349  KANKTCDTITLSWKHPASDGGMYIEDYIISVGSR-KEATIDDKK-QMFKLESKFQRNTKY 406

Query: 3940 SEALTQMEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAP 3999
            + ++             +Y+T D  Y +    PP+ +T  Q++++  E   T +E     
Sbjct: 407  NVSIQARNKAGPGERETLYITTDK-YCI--PSPPK-ITSKQTESNGPEYMVT-WEAPDFD 461

Query: 4000 VGDPNMK--VEWFFNGKPL 4016
              DP++K  VEW    +P+
Sbjct: 462  GHDPDLKYRVEWTRTSEPV 480



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 11/88 (12%)

Query: 929  FEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYN 988
            FE   E  G S L VEW ++G P     +     + G   + I+S+ + DA  +TC A N
Sbjct: 176  FEVACEATGASPLSVEWKRNGSPYLGQEK-----SNGKSVIKIQSLKLSDAAQFTCTASN 230

Query: 989  AI---GQ---ATTSANLTIVTKKDIIAE 1010
             +   G+   +T S  LT+     ++ E
Sbjct: 231  GLQFNGKDVVSTKSFKLTVEAPPTVVLE 258



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 15/38 (39%), Positives = 23/38 (60%)

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVA 2202
            G   LD++ +   D GT++C+A NK G  +N   LK+A
Sbjct: 302  GTAQLDVVTSVTSDFGTFICEANNKRGRKLNNIMLKMA 339



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)

Query: 1647 SGTYTCRAINALGEAVTSGIAIVHSKKSIYLESQHEGALPRLN-QLEDTSKYQ------- 1698
            +G Y CR   ++ +A     A  +   S Y+   ++G L   N Q  D + Y+       
Sbjct: 88   AGKYECRG--SINKATVELEATCNPNPSKYV--MNDGCLVIKNLQTSDVASYKCLAKNNI 143

Query: 1699 -RHSAQDEV--ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEA 1755
               SA+ EV  I++  V T  +KD       A  FE      G   L VEW RNG P   
Sbjct: 144  GEISAEVEVTRISEQAVITSDIKDATKVVGDA--FEVACEATGASPLSVEWKRNGSPYLG 201

Query: 1756 SNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINEL---GEAVTSSTLF 1801
              +       G   + ++ +   D+  +TC A N L   G+ V S+  F
Sbjct: 202  QEKSN-----GKSVIKIQSLKLSDAAQFTCTASNGLQFNGKDVVSTKSF 245


>SB_43033| Best HMM Match : I-set (HMM E-Value=3.3e-18)
          Length = 93

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 3/91 (3%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P+I      + V EG+ +  SC   G+P P+ QW+K D         + S    +  L  
Sbjct: 3    PDISTHPSPQTVTEGENVTLSCVAEGRPTPSYQWFKDDSPFDAENNTRAS--LSQGNLIF 60

Query: 4683 SEAFPEDEGDYKCVAYNSAGRVTVA-AKLKV 4712
            ++   +D G Y C+A NS   VT + A+L V
Sbjct: 61   TKISRDDHGQYYCLANNSVSNVTSSIAQLNV 91



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 4/81 (4%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           VTEG+     C   GRP P   WF +D     + N +  +++ GN  L+ T ++  D G 
Sbjct: 14  VTEGENVTLSCVAEGRPTPSYQWFKDDSPFDAENNTRASLSQ-GN--LIFTKISRDDHGQ 70

Query: 463 VTCVARNK-SGETAFQCRLNV 482
             C+A N  S  T+   +LNV
Sbjct: 71  YYCLANNSVSNVTSSIAQLNV 91



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 3/82 (3%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASD 557
           S   V EGE V L+  A G PTP   W KD  P       R     G   L   +    D
Sbjct: 10  SPQTVTEGENVTLSCVAEGRPTPSYQWFKDDSPFDAENNTRASLSQG--NLIFTKISRDD 67

Query: 558 AAWYQCTAQN-VAGSTATRARL 578
              Y C A N V+  T++ A+L
Sbjct: 68  HGQYYCLANNSVSNVTSSIAQL 89



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 2787 EGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIY 2846
            EG+N+   C  E    PT   +WF ++ P  +    +++   S  +L  T    +D G Y
Sbjct: 16   EGENVTLSCVAEGR--PTPSYQWFKDDSPFDAENNTRAS--LSQGNLIFTKISRDDHGQY 71

Query: 2847 TCKATNSKGSATTS 2860
             C A NS  + T+S
Sbjct: 72   YCLANNSVSNVTSS 85



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 5/88 (5%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVT 2701
            P  +TH  S   + EG++V L    E R  P+   +WFK+          +++   G   
Sbjct: 3    PDISTH-PSPQTVTEGENVTLSCVAEGRPTPSY--QWFKDDSPFDAENNTRASLSQG--N 57

Query: 2702 LSINSLRNDDSGIYTCKATNLLGEAVST 2729
            L    +  DD G Y C A N +    S+
Sbjct: 58   LIFTKISRDDHGQYYCLANNSVSNVTSS 85



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%)

Query: 1853 PTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGE 1912
            P  ++EG++    C  E  P P+   +W+ +     + +  R S   G   L    +  +
Sbjct: 11   PQTVTEGENVTLSCVAEGRPTPSY--QWFKDDSPFDAENNTRASLSQG--NLIFTKISRD 66

Query: 1913 DSGEYTCKAINNLGQAVSSI-RLNV 1936
            D G+Y C A N++    SSI +LNV
Sbjct: 67   DHGQYYCLANNSVSNVTSSIAQLNV 91



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 908 KPEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYV 967
           KP+  T    Q ++ EG         E  G  T   +W KD  P +A +      + G +
Sbjct: 2   KPDISTHPSPQ-TVTEGENVTLSCVAE--GRPTPSYQWFKDDSPFDAENNTRASLSQGNL 58

Query: 968 ALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
             T   ++  D G Y C A N++   T+S
Sbjct: 59  IFT--KISRDDHGQYYCLANNSVSNVTSS 85



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 4/75 (5%)

Query: 85  QGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEY 144
           +G N        G PTP   W +  +P    N  + R +   G+  L+  +I   D G+Y
Sbjct: 16  EGENVTLSCVAEGRPTPSYQWFKDDSPFDAEN--NTRASLSQGN--LIFTKISRDDHGQY 71

Query: 145 TCTARNQYGEAICSV 159
            C A N       S+
Sbjct: 72  YCLANNSVSNVTSSI 86


>SB_15415| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1390

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 5/74 (6%)

Query: 4643 SCKIVGKPLPTVQWY-KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSA 4701
            +C+  G P PT+ WY +G  L   +KY   +  +    L+I     ED G Y C A N+ 
Sbjct: 729  NCEAYGSPQPTMFWYSRGKDLTNRNKYTHFNNGS----LKIMNLEKEDTGKYMCTASNTL 784

Query: 4702 GRVTVAAKLKVTQP 4715
            G+ TV  +L+V  P
Sbjct: 785  GKQTVMRRLRVQIP 798



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 3/77 (3%)

Query: 1869 EPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA 1928
            E Y  P   + WY  GK L + ++Y   N+    +L I+ +  ED+G+Y C A N LG+ 
Sbjct: 731  EAYGSPQPTMFWYSRGKDLTNRNKYTHFNN---GSLKIMNLEKEDTGKYMCTASNTLGKQ 787

Query: 1929 VSSIRLNVQSKESIIRD 1945
                RL VQ   S  +D
Sbjct: 788  TVMRRLRVQIPPSPPQD 804



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 291 GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTS 350
           G+P+P + W+  G+ L N NK+   T  N+ +L++ N +K D+G Y   A N  G     
Sbjct: 734 GSPQPTMFWYSRGKDLTNRNKY---THFNNGSLKIMNLEKEDTGKYMCTASNTLGKQTVM 790

Query: 351 GYLAVESP 358
             L V+ P
Sbjct: 791 RRLRVQIP 798



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 13/132 (9%)

Query: 737 TSQHPETLQY--IQQLEDYSKYQHQESIEEQTSQRPQ---FIRPLQD-LGELQEGRNAHF 790
           T    +TL Y  ++ +         E + ++T +R +   F R L D L + +     + 
Sbjct: 671 TDMESDTLYYFWVRAITAVGIGNASEVVSKRTMERIKASIFDRTLPDTLSKWKTFAILNC 730

Query: 791 EAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNK 850
           EA  +P   PTM   WY  G+ +T  ++ T  FN G  SL IM+L  ED G Y   A N 
Sbjct: 731 EAYGSP--QPTMF--WYSRGKDLTNRNKYTH-FNNG--SLKIMNLEKEDTGKYMCTASNT 783

Query: 851 LGEAISTASIRV 862
           LG+      +RV
Sbjct: 784 LGKQTVMRRLRV 795



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 6/112 (5%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSR-TADEY-- 4678
            P  I+ P  D+ V     + FSC  +G     + W+ G K +  S   Q+ R T D    
Sbjct: 2    PAVIVSPPSDRSVEVFGEMAFSCVAIGNLPIMLSWFNGSKQMVDSSRVQIMRYTKDNAHL 61

Query: 4679 ---TLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
               TL +S+    D  +Y C   N  GR     K+ V +     ++P ++ +
Sbjct: 62   VNGTLHVSDLRLWDTKEYSCRVGNQFGRDEKTFKITVQESPSNPSVPRVSDI 113



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 3/68 (4%)

Query: 2134 EPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEA 2193
            E    P  T+ W+  G+ +   ++Y  TH F   +L I+    ED+G YMC A+N LG+ 
Sbjct: 731  EAYGSPQPTMFWYSRGKDLTNRNKY--TH-FNNGSLKIMNLEKEDTGKYMCTASNTLGKQ 787

Query: 2194 VNTCTLKV 2201
                 L+V
Sbjct: 788  TVMRRLRV 795



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 3/55 (5%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYG 4055
            G P   + W+  GK L ++N++T   +     MN   +  ED+G+Y+C A+N  G
Sbjct: 734  GSPQPTMFWYSRGKDLTNRNKYTHFNNGSLKIMN---LEKEDTGKYMCTASNTLG 785



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 3/69 (4%)

Query: 2796 NVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKG 2855
            N E    P   + W+   K L +  +Y  TH F+  SL I +  +ED+G Y C A+N+ G
Sbjct: 729  NCEAYGSPQPTMFWYSRGKDLTNRNKY--TH-FNNGSLKIMNLEKEDTGKYMCTASNTLG 785

Query: 2856 SATTSGSLR 2864
              T    LR
Sbjct: 786  KQTVMRRLR 794



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 17/62 (27%), Positives = 36/62 (58%), Gaps = 3/62 (4%)

Query: 3312 PDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKAN 3371
            P   + W+  GK L + ++Y  F++  + I+++    +E++G+Y C A+N LG+ +    
Sbjct: 736  PQPTMFWYSRGKDLTNRNKYTHFNNGSLKIMNL---EKEDTGKYMCTASNTLGKQTVMRR 792

Query: 3372 LK 3373
            L+
Sbjct: 793  LR 794



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 3/48 (6%)

Query: 1613 WYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGE 1660
            WY   K L + +++T  NN    +L IM+   ED+G Y C A N LG+
Sbjct: 742  WYSRGKDLTNRNKYTHFNNG---SLKIMNLEKEDTGKYMCTASNTLGK 786



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 9/107 (8%)

Query: 1030 SKRTEEEVKITQKPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSA 1089
            SKRT E +K +   R L       K       + EA   PQ     T+ WY  GK +T+ 
Sbjct: 699  SKRTMERIKASIFDRTLPDTLSKWKTFA--ILNCEAYGSPQP----TMFWYSRGKDLTNR 752

Query: 1090 NRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
            N+   Y  F   +L I ++  ED+G Y   A N  G+  +   + V+
Sbjct: 753  NK---YTHFNNGSLKIMNLEKEDTGKYMCTASNTLGKQTVMRRLRVQ 796



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%)

Query: 509 VLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
           +LN  A G+P P + W   G   + N     H + G  +L I   +  D   Y CTA N 
Sbjct: 727 ILNCEAYGSPQPTMFWYSRGKD-LTNRNKYTHFNNG--SLKIMNLEKEDTGKYMCTASNT 783

Query: 569 AGSTATRARL 578
            G      RL
Sbjct: 784 LGKQTVMRRL 793



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 5/95 (5%)

Query: 1308 MQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDY 1367
            ++A  F R L +  +   T   L C  +  G     + W+  GK +   +++     F+ 
Sbjct: 706  IKASIFDRTLPDTLSKWKTFAILNC--EAYGSPQPTMFWYSRGKDLTNRNKYT---HFNN 760

Query: 1368 VALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             +L ++++  ED+G Y C A+N LG+      LRV
Sbjct: 761  GSLKIMNLEKEDTGKYMCTASNTLGKQTVMRRLRV 795



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 20/54 (37%), Positives = 33/54 (61%), Gaps = 3/54 (5%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGE 3912
            P+  + WY  GK L + ++Y T ++ G  SL I+ +  ED+G+Y+C A N  G+
Sbjct: 736  PQPTMFWYSRGKDLTNRNKY-THFNNG--SLKIMNLEKEDTGKYMCTASNTLGK 786



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 5/63 (7%)

Query: 2007 PTMRVEWYCNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSS 2066
            PTM   WY  G+ +   +++ T ++ G  +L I+    EDTG YMC A+N +G+      
Sbjct: 738  PTMF--WYSRGKDLTNRNKY-THFNNG--SLKIMNLEKEDTGKYMCTASNTLGKQTVMRR 792

Query: 2067 VKV 2069
            ++V
Sbjct: 793  LRV 795



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 3450 PNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTAS 3509
            P   + WY  GK L   +++  F +    I+ +     ED+G+Y+C A N  G+      
Sbjct: 736  PQPTMFWYSRGKDLTNRNKYTHFNNGSLKIMNLEK---EDTGKYMCTASNTLGKQTVMRR 792

Query: 3510 MKVQ 3513
            ++VQ
Sbjct: 793  LRVQ 796



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLGE 2459
            G P   + W+   K + + ++ T    F   S+ I ++  ED G YMC ASN LG+
Sbjct: 734  GSPQPTMFWYSRGKDLTNRNKYTH---FNNGSLKIMNLEKEDTGKYMCTASNTLGK 786



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 8/73 (10%)

Query: 412 DCRVTGRPYPEVTWFINDRQI--RDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
           +C   G P P + W+   + +  R+ Y H        N +L I N+   D+G   C A N
Sbjct: 729 NCEAYGSPQPTMFWYSRGKDLTNRNKYTH------FNNGSLKIMNLEKEDTGKYMCTASN 782

Query: 470 KSGETAFQCRLNV 482
             G+     RL V
Sbjct: 783 TLGKQTVMRRLRV 795



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 5/58 (8%)

Query: 97  GNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
           G+P P + W  +   L   NKY+  +N      SL I  +   D G+Y CTA N  G+
Sbjct: 734 GSPQPTMFWYSRGKDLTNRNKYT-HFNNG----SLKIMNLEKEDTGKYMCTASNTLGK 786



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 3/64 (4%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   + W+  G  LT   R K T  F   +L I +L  +D+G Y C A+N LG+      
Sbjct: 736  PQPTMFWYSRGKDLTN--RNKYTH-FNNGSLKIMNLEKEDTGKYMCTASNTLGKQTVMRR 792

Query: 2732 IKIE 2735
            ++++
Sbjct: 793  LRVQ 796



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P+  + W   G  +   N+ T  ++     +N++    ED+G Y C A N LG+    
Sbjct: 734  GSPQPTMFWYSRGKDLTNRNKYTHFNNGSLKIMNLE---KEDTGKYMCTASNTLGKQTVM 790

Query: 1798 STLFVQ 1803
              L VQ
Sbjct: 791  RRLRVQ 796



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 8/82 (9%)

Query: 3711 GPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRV----HTLNDFGFI--ALDIDYIYARD 3764
            G + F C    +G+  + + WF+  +     SRV    +T ++   +   L +  +   D
Sbjct: 18   GEMAFSCVA--IGNLPIMLSWFNGSKQMVDSSRVQIMRYTKDNAHLVNGTLHVSDLRLWD 75

Query: 3765 AGEYTCRATNKWGSATTTAKIT 3786
              EY+CR  N++G    T KIT
Sbjct: 76   TKEYSCRVGNQFGRDEKTFKIT 97



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 3593 WFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
            W+  GK L   ++    N+     L+I  + + D G Y C A+N  G+ TV  +L+V+
Sbjct: 742  WYSRGKDLTNRNKYTHFNNGS---LKIMNLEKEDTGKYMCTASNTLGKQTVMRRLRVQ 796



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 3/55 (5%)

Query: 1480 WFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRL 1534
            W+  G+ +T  +R +  H F   +L I++L  ED+G Y C A N +G   V  RL
Sbjct: 742  WYSRGKDLT--NRNKYTH-FNNGSLKIMNLEKEDTGKYMCTASNTLGKQTVMRRL 793



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 3/58 (5%)

Query: 661 EPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATG 718
           E  G P   + W   G+ +   +++T    F   SL +++L  +D+G+Y C A +  G
Sbjct: 731 EAYGSPQPTMFWYSRGKDLTNRNKYT---HFNNGSLKIMNLEKEDTGKYMCTASNTLG 785



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAG 2590
            G P     WY  G +L   +R + TH F   +L I ++   D G YMC A N  G
Sbjct: 734  GSPQPTMFWYSRGKDLT--NRNKYTH-FNNGSLKIMNLEKEDTGKYMCTASNTLG 785


>SB_42486| Best HMM Match : Pkinase_Tyr (HMM E-Value=0)
          Length = 1554

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 44/291 (15%)

Query: 4550 NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLP-AT 4608
            N K +QP    K+++ D  YT+L   AY QD+G+Y+C A N       D E + + P A 
Sbjct: 71   NEKPLQP---GKVIKTDDVYTILNF-AY-QDAGQYQCKATN------LDGETIFTDPNAC 119

Query: 4609 KDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK----GDKLIK 4664
            K   +P       P   ++PL    +++G +  F+C        T++W K    G +   
Sbjct: 120  KVFGRPNV----IPDVTVDPLYAVQLSQGDSFNFTCS--SATHTTLKWTKRPKTGSESDV 173

Query: 4665 PSKYFQM----SRTADEYTLRISEAFPEDEGDYKCV-AYNSAGRVTVAAKLKVTQPDQAD 4719
            PS    +    S+      L I  A P D   YKC+  YN      +A+ L V + ++  
Sbjct: 174  PSSQTVLIKDTSKNQQRLILMIRNAQPSDTATYKCILTYNGQEHYKLAS-LIVYKNEKPV 232

Query: 4720 NLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIP----------ETPDF-- 4767
                 +    + + E    +         +P   W ++G  I           ET  +  
Sbjct: 233  ITSHSSTTGPVTMQEPSDVEIFCSFQGYPQPKNTWSKDGTEITFGGCIAGQPCETKKYIL 292

Query: 4768 ----QMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
                ++  E  + + + G  Y +D G +TC A  + G  +    L V+  T
Sbjct: 293  KTKRKLSTEYISHLTIKGARYPDDHGIYTCSAANSLGVAKADITLNVEVPT 343



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 48/212 (22%), Positives = 81/212 (38%), Gaps = 29/212 (13%)

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVTEGK--MTRFDCRVTGRPYPEVTWFIND----- 429
           R   + I++   A+ P  +    D+ V + K  +   +C+V+G P P V W+ +      
Sbjct: 482 RIVNDSIKVEVLAVTPPIISEMPDQTVKKEKTDIVEVNCKVSGYPKPTVIWYKHSPGETE 541

Query: 430 ----RQIRDDYNHKILVNESGNHALMITNVTLS----------DSGVVTCVARNKSGETA 475
                QI D             +   + ++              SG   C+A N+ GE  
Sbjct: 542 WRRLSQIPDLVRSNGCTQSRSGYYFYLDSIGSPLVICQPRHELHSGKYKCIATNELGEDQ 601

Query: 476 FQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNP 535
               LNV E  +++ PK       L+V        + +A G P P + W +       + 
Sbjct: 602 RIASLNVEEGARILKPK----SKLLSVALDTNFNQSCQASGNPVPTVQWMRHE----KSG 653

Query: 536 ELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           +  + T  G++ L IP+    D   Y CTA N
Sbjct: 654 DKLLSTGLGSALLVIPKVMTKDLTNYTCTAAN 685



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 46/210 (21%), Positives = 80/210 (38%), Gaps = 22/210 (10%)

Query: 263 VSPPKIAQKPRNSKLQEGAD-AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHT 321
           V+PP I++ P  +  +E  D  +   ++SG P+P V W+K+        +   I      
Sbjct: 495 VTPPIISEMPDQTVKKEKTDIVEVNCKVSGYPKPTVIWYKHSPGETEWRRLSQIP----D 550

Query: 322 TLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEE 381
            +R     +S SG+Y  L    +  ++      + S     +            QR    
Sbjct: 551 LVRSNGCTQSRSGYYFYLDSIGSPLVICQPRHELHSGKYKCIATNE----LGEDQRIASL 606

Query: 382 RIEISEKALAP--QFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
            +E   + L P  + + V  D +  +       C+ +G P P V W  +++        K
Sbjct: 607 NVEEGARILKPKSKLLSVALDTNFNQ------SCQASGNPVPTVQWMRHEKS-----GDK 655

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARN 469
           +L    G+  L+I  V   D    TC A N
Sbjct: 656 LLSTGLGSALLVIPKVMTKDLTNYTCTAAN 685



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 56/230 (24%), Positives = 88/230 (38%), Gaps = 32/230 (13%)

Query: 4589 INSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA--IEFSCKI 4646
            +N +G   CDA  +            + +     P II  + D+ V + +   +E +CK+
Sbjct: 463  VNDSGVYSCDALALRPQLNRIVNDSIKVEVLAVTPPIISEMPDQTVKKEKTDIVEVNCKV 522

Query: 4647 VGKPLPTVQWYK---GD----------KLIKPSKYFQMSRTADEYTLRISEAF----PED 4689
             G P PTV WYK   G+           L++ +   Q       Y   I        P  
Sbjct: 523  SGYPKPTVIWYKHSPGETEWRRLSQIPDLVRSNGCTQSRSGYYFYLDSIGSPLVICQPRH 582

Query: 4690 E---GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITS 4746
            E   G YKC+A N  G     A L V   + A  L   + L  + +          Q + 
Sbjct: 583  ELHSGKYKCIATNELGEDQRIASLNV--EEGARILKPKSKLLSVAL--DTNFNQSCQASG 638

Query: 4747 KIKPTIQWLREGALIPETPDFQMIHEG-NNAVLLIGNTYEEDTGTFTCRA 4795
               PT+QW+R      E    +++  G  +A+L+I     +D   +TC A
Sbjct: 639  NPVPTVQWMRH-----EKSGDKLLSTGLGSALLVIPKVMTKDLTNYTCTA 683



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 19/137 (13%)

Query: 4563 LEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAP 4622
            L+  G+  ++    +   SGKY+C+A N  GE +  A   V   A   KPK +  +    
Sbjct: 568  LDSIGSPLVICQPRHELHSGKYKCIATNELGEDQRIASLNVEEGARILKPKSKLLS---- 623

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
                       VA       SC+  G P+PTVQW + +K    S    +S       L I
Sbjct: 624  -----------VALDTNFNQSCQASGNPVPTVQWMRHEK----SGDKLLSTGLGSALLVI 668

Query: 4683 SEAFPEDEGDYKCVAYN 4699
             +   +D  +Y C A N
Sbjct: 669  PKVMTKDLTNYTCTAAN 685



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 21/49 (42%), Positives = 26/49 (53%), Gaps = 5/49 (10%)

Query: 2016 NGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTT 2064
            N +P+Q G   KT  D  Y  L+  Y   +D G Y CKATN  GE + T
Sbjct: 71   NEKPLQPGKVIKT--DDVYTILNFAY---QDAGQYQCKATNLDGETIFT 114



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/82 (28%), Positives = 32/82 (39%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           LMI N   SD+    C+      E      L V + E+ V          + ++E   V 
Sbjct: 193 LMIRNAQPSDTATYKCILTYNGQEHYKLASLIVYKNEKPVITSHSSTTGPVTMQEPSDVE 252

Query: 510 LNARAVGTPTPRITWQKDGVPI 531
           +     G P P+ TW KDG  I
Sbjct: 253 IFCSFQGYPQPKNTWSKDGTEI 274



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)

Query: 4095 QVTPEQVVEESKARCPPVFVSLPD-AVTVEEGEWARFCCRVTGHPKPRVMW 4144
            ++  + +  E  A  PP+   +PD  V  E+ +     C+V+G+PKP V+W
Sbjct: 482  RIVNDSIKVEVLAVTPPIISEMPDQTVKKEKTDIVEVNCKVSGYPKPTVIW 532



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/64 (43%), Positives = 33/64 (51%), Gaps = 7/64 (10%)

Query: 3595 HNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEA--TVSCKLQVKGR 3652
            +N KPL  G  +KT  D  + IL     YQ DAG Y CKATN  GE   T     +V GR
Sbjct: 70   YNEKPLQPGKVIKT--DDVYTILNFA--YQ-DAGQYQCKATNLDGETIFTDPNACKVFGR 124

Query: 3653 QGII 3656
              +I
Sbjct: 125  PNVI 128



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 7/80 (8%)

Query: 2137 NDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYA----EDSGTYMCKATNKLGE 2192
            ND + T    +  QK   G+  +       +  D +YT      +D+G Y CKATN  GE
Sbjct: 52   NDENATTTLLYR-QKFMGGYNEKPLQPGKVIKTDDVYTILNFAYQDAGQYQCKATNLDGE 110

Query: 2193 AVNT--CTLKVAGHRNIILD 2210
             + T     KV G  N+I D
Sbjct: 111  TIFTDPNACKVFGRPNVIPD 130



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 18/102 (17%)

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSG----------HRY--RTSNDF 1899
            GP  + E       C  + YP P  +  W  +G  +  G           +Y  +T    
Sbjct: 241  GPVTMQEPSDVEIFCSFQGYPQP--KNTWSKDGTEITFGGCIAGQPCETKKYILKTKRKL 298

Query: 1900 GFAALDILTV----YGEDSGEYTCKAINNLGQAVSSIRLNVQ 1937
                +  LT+    Y +D G YTC A N+LG A + I LNV+
Sbjct: 299  STEYISHLTIKGARYPDDHGIYTCSAANSLGVAKADITLNVE 340



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 14/27 (51%), Positives = 16/27 (59%)

Query: 1376 YPEDSGVYTCQATNQLGEAVTSCALRV 1402
            YP+D G+YTC A N LG A     L V
Sbjct: 313  YPDDHGIYTCSAANSLGVAKADITLNV 339



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 39/166 (23%), Positives = 68/166 (40%), Gaps = 14/166 (8%)

Query: 4655 QWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQ 4714
            Q + G    KP +  ++ +T D YT+ ++ A+ +D G Y+C A N  G            
Sbjct: 64   QKFMGGYNEKPLQPGKVIKTDDVYTI-LNFAY-QDAGQYQCKATNLDGETIFTDPNACKV 121

Query: 4715 PDQADNLPALT--PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPET--PDFQMI 4770
              + + +P +T  PL  + + +G    F    +S    T++W +      E+  P  Q +
Sbjct: 122  FGRPNVIPDVTVDPLYAVQLSQGD--SFNFTCSSATHTTLKWTKRPKTGSESDVPSSQTV 179

Query: 4771 ------HEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
                        +L+I N    DT T+ C  T    +    A L+V
Sbjct: 180  LIKDTSKNQQRLILMIRNAQPSDTATYKCILTYNGQEHYKLASLIV 225



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 13/25 (52%), Positives = 20/25 (80%)

Query: 3348 YEENSGEYECVATNKLGRDSTKANL 3372
            +E +SG+Y+C+ATN+LG D   A+L
Sbjct: 582  HELHSGKYKCIATNELGEDQRIASL 606



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 13/26 (50%), Positives = 17/26 (65%)

Query: 2710 DDSGIYTCKATNLLGEAVSTASIKIE 2735
            DD GIYTC A N LG A +  ++ +E
Sbjct: 315  DDHGIYTCSAANSLGVAKADITLNVE 340


>SB_12208| Best HMM Match : ig (HMM E-Value=6.9e-30)
          Length = 474

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 54/201 (26%), Positives = 79/201 (39%), Gaps = 19/201 (9%)

Query: 666 PTMKIEWLKNGQSIEASSRFTSIF--RFGYISLDMLSLNIQ--DSGEYTCRAVSATGVAE 721
           P  K  W KNG  +  S+     +  + GY   D++  N+Q  D G Y+C A+      E
Sbjct: 37  PAEKFIWRKNGHLLSNSTIVYPSYTPQLGYWE-DLVISNVQLKDEGSYSCTAIQGNSQDE 95

Query: 722 TKAVLHVTPRATIERTSQHPETLQYIQQLEDYSKYQHQESIEEQTSQRPQFIRPLQDLGE 781
               ++V        T      L +   L  +      E+IEE  +  P          E
Sbjct: 96  DWYTVNVYGNG--HNTETLKNILGHSHALTGHFLII-LENIEEHVTPPPA---TALFYVE 149

Query: 782 LQEGRNAHFEAQLTPVSDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAG 841
           L  G  A    +      P +R  WYK+G P++  S+I        VSL+I   R  D G
Sbjct: 150 LSRGDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQSDQG 201

Query: 842 SYTVRAVNKLGEAISTASIRV 862
            Y  RA N +G  I    I++
Sbjct: 202 MYYCRANNTVGSEIRPILIKM 222



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 486 EQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGA 545
           E+ V P        + +  G+  V+  +A G P P + W K+G+P+ P+ ++        
Sbjct: 134 EEHVTPPPATALFYVELSRGDRAVVRCKADGWPPPYLRWYKEGMPLSPHSKIE------E 187

Query: 546 STLDIPRAKASDAAWYQCTAQNVAGS 571
            +L I  A+ SD   Y C A N  GS
Sbjct: 188 VSLHITFARQSDQGMYYCRANNTVGS 213



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 52/216 (24%), Positives = 84/216 (38%), Gaps = 16/216 (7%)

Query: 1989 VTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTY--DFGYVA-LDILYAYAE 2045
            V  G+ + L  ++  +N P  +  W  NG  +        +Y    GY   L I     +
Sbjct: 20   VWPGNNITLNCSVI-LNGPAEKFIWRKNGHLLSNSTIVYPSYTPQLGYWEDLVISNVQLK 78

Query: 2046 DTGTYMCKATNAVGEAVTTSSVKVDAKSGLYLDTLDEQRLKKIQELEKYERPKPIEEEQP 2105
            D G+Y C A     +     +V V   +G   +TL +  L     L  +     +E  + 
Sbjct: 79   DEGSYSCTAIQGNSQDEDWYTVNVYG-NGHNTETL-KNILGHSHALTGHFLII-LENIEE 135

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFG 2165
               P   TAL  +E L  GDRA   C+ +    P+L   W+  G  +    +        
Sbjct: 136  HVTPPPATALFYVE-LSRGDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE----- 187

Query: 2166 YVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
             V+L I +    D G Y C+A N +G  +    +K+
Sbjct: 188  -VSLHITFARQSDQGMYYCRANNTVGSEIRPILIKM 222



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRI--KTVSDFGFVV-LDIAYTQ 3215
            +G+  G +    C+V+ ++ P  K  W  NG  + +ST +        G+   L I+  Q
Sbjct: 18   QGVWPGNNITLNCSVI-LNGPAEKFIWRKNGHLLSNSTIVYPSYTPQLGYWEDLVISNVQ 76

Query: 3216 NHDSGEYVCRAYNKYGEDFTRATINCYGKG 3245
              D G Y C A     +D    T+N YG G
Sbjct: 77   LKDEGSYSCTAIQGNSQDEDWYTVNVYGNG 106



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 8/85 (9%)

Query: 2651 YDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRND 2710
            Y +L  G    +  + +    P L+  W+K G+ L+  ++++       V+L I   R  
Sbjct: 147  YVELSRGDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQS 198

Query: 2711 DSGIYTCKATNLLGEAVSTASIKIE 2735
            D G+Y C+A N +G  +    IK++
Sbjct: 199  DQGMYYCRANNTVGSEIRPILIKMK 223



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 44/177 (24%), Positives = 71/177 (40%), Gaps = 21/177 (11%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            ++ G      CK  G P P ++WYK    + P          +E +L I+ A   D+G Y
Sbjct: 150  LSRGDRAVVRCKADGWPPPYLRWYKEGMPLSPHS------KIEEVSLHITFARQSDQGMY 203

Query: 4694 KCVAYNSAGRV--TVAAKLK-VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKP 4750
             C A N+ G     +  K+K VT   +A +    T L   V      +    +       
Sbjct: 204  YCRANNTVGSEIRPILIKMKQVTPRVKAKDHYVATRLGSTVSISCTASNVNLEF-----D 258

Query: 4751 TIQWLREG--ALIPETPDFQ----MIHEGN-NAVLLIGNTYEEDTGTFTCRATTAAG 4800
            T +W R G  A + ++  F       +EG+  + L+I     +D G + C   T+ G
Sbjct: 259  TTKWTRNGTEASVQQSQRFHTRDLYSYEGSMESTLIIKGVRIQDFGCYKCTVATSNG 315



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 48/190 (25%), Positives = 72/190 (37%), Gaps = 18/190 (9%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIH--DFGYVA-LDIIDLIAEDSGIYTCRAVNLVGTDEVSCR 1533
            K  W KNG  ++      P +    GY   L I ++  +D G Y+C A+     DE    
Sbjct: 40   KFIWRKNGHLLSNSTIVYPSYTPQLGYWEDLVISNVQLKDEGSYSCTAIQGNSQDEDWY- 98

Query: 1534 LTCRSTTDIVRSTQNEAGLEQIQVLEDRSKYHRTDMVDEVTTQA-PICTTSLKNVEIKEG 1592
                 T ++  +  N   L+ I         H   +++ +     P   T+L  VE+  G
Sbjct: 99   -----TVNVYGNGHNTETLKNILGHSHALTGHFLIILENIEEHVTPPPATALFYVELSRG 153

Query: 1593 QRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTC 1652
             RA    +        L+  WY    PL   S+  E      V+L I      D G Y C
Sbjct: 154  DRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQSDQGMYYC 205

Query: 1653 RAINALGEAV 1662
            RA N +G  +
Sbjct: 206  RANNTVGSEI 215



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 6/55 (10%)

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
            P   + WY  G P+   ++I+ VS      L I + +  D G Y CRA N  G +
Sbjct: 166  PPPYLRWYKEGMPLSPHSKIEEVS------LHITFARQSDQGMYYCRANNTVGSE 214



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 8/94 (8%)

Query: 1855 KLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDS 1914
            +LS G  A   C+ + +P P +R  WY  G  L    +          +L I      D 
Sbjct: 149  ELSRGDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQSDQ 200

Query: 1915 GEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQH 1948
            G Y C+A N +G  +  I + ++     ++   H
Sbjct: 201  GMYYCRANNTVGSEIRPILIKMKQVTPRVKAKDH 234



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 6/84 (7%)

Query: 3841 VEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSG 3900
            VE S G R   R +    P   + WY+ G  L    +   V      SL I +    D G
Sbjct: 148  VELSRGDRAVVRCKADGWPPPYLRWYKEGMPLSPHSKIEEV------SLHITFARQSDQG 201

Query: 3901 EYICRAVNDFGEDFTKATISCKKL 3924
             Y CRA N  G +     I  K++
Sbjct: 202  MYYCRANNTVGSEIRPILIKMKQV 225



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 8/69 (11%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            GD     C  +    P L+  W+    PL   ++ +       VSL IT   + D G+Y 
Sbjct: 153  GDRAVVRCKADGWPPPYLR--WYKEGMPLSPHSKIEE------VSLHITFARQSDQGMYY 204

Query: 2848 CKATNSKGS 2856
            C+A N+ GS
Sbjct: 205  CRANNTVGS 213



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/102 (21%), Positives = 42/102 (41%), Gaps = 8/102 (7%)

Query: 1301 VREDITVMQAPQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFR 1360
            + E+I     P  + AL  +E   G    + C+    G     + W+  G P+       
Sbjct: 129  ILENIEEHVTPPPATALFYVELSRGDRAVVRCKAD--GWPPPYLRWYKEGMPLS------ 180

Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            P  + + V+L +      D G+Y C+A N +G  +    +++
Sbjct: 181  PHSKIEEVSLHITFARQSDQGMYYCRANNTVGSEIRPILIKM 222



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 6/55 (10%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            G P   + W++    +   S+I +      VS+ I+  R  D+G+Y CRA+N +G
Sbjct: 164  GWPPPYLRWYKEGMPLSPHSKIEE------VSLHITFARQSDQGMYYCRANNTVG 212



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 4/66 (6%)

Query: 2391 GQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRI--TKTHDFGY-VSMTISHVRDEDEG 2447
            G     +C +I  G P  K  W +N  L+ +S+ +  + T   GY   + IS+V+ +DEG
Sbjct: 23   GNNITLNCSVILNG-PAEKFIWRKNGHLLSNSTIVYPSYTPQLGYWEDLVISNVQLKDEG 81

Query: 2448 VYMCRA 2453
             Y C A
Sbjct: 82   SYSCTA 87



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 9/93 (9%)

Query: 70  SPPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           +PP    +F     ++G  A    K  G P P + W ++  PL   +K          +V
Sbjct: 138 TPPPATALFY-VELSRGDRAVVRCKADGWPPPYLRWYKEGMPLSPHSKIE--------EV 188

Query: 130 SLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
           SL I      D+G Y C A N  G  I  + I+
Sbjct: 189 SLHITFARQSDQGMYYCRANNTVGSEIRPILIK 221


>SB_5499| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 183

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 25/66 (37%), Positives = 37/66 (56%), Gaps = 4/66 (6%)

Query: 281 ADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEIITTHNHTTLRVRNTQKSDSGHYTLL 339
           A A+  V +  NP+P+VTWFKNG R+ ++  K++  +     TL +      D+G YT  
Sbjct: 109 ASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSA---DTLEIAGLVPQDTGIYTCR 165

Query: 340 AENPNG 345
           AEN  G
Sbjct: 166 AENARG 171



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 43/190 (22%), Positives = 66/190 (34%), Gaps = 9/190 (4%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PP I+    D++    Q I F C   G P P V W       +P+             L 
Sbjct: 2    PPRIVSEPTDQVATIHQNITFVCDTQGVPKPRVSWQNSQG--RPADRDPRITVLQSGALH 59

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK 4741
            I    P     ++   +N      +  +L +      D    L       +     A+  
Sbjct: 60   IRGGVPTPRVTWQ---HNGRNLQYMTPRLVIRDARPQD--AGLYRCTGTNLAGRASAETS 114

Query: 4742 TQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
              + S  KP + W + G  +P   D     + +   L I     +DTG +TCRA  A G 
Sbjct: 115  VTVRSNPKPKVTWFKNGYRVPL--DDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARGH 172

Query: 4802 VETSAKLVVK 4811
               +  LVV+
Sbjct: 173  DTWNITLVVQ 182



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 4/66 (6%)

Query: 2794 ECNVEPSRDPTLKIEWFFNNKPLP-SGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852
            E +V    +P  K+ WF N   +P    +YK T   S  +L+I     +D+GIYTC+A N
Sbjct: 112  ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAEN 168

Query: 2853 SKGSAT 2858
            ++G  T
Sbjct: 169  ARGHDT 174



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 2663 EAQVEPRTDPNLKIEWFKNGVTLTTG-ARLKSTFDFGLVTLSINSLRNDDSGIYTCKATN 2721
            E  V  R++P  K+ WFKNG  +     + K T      TL I  L   D+GIYTC+A N
Sbjct: 112  ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAEN 168

Query: 2722 LLG 2724
              G
Sbjct: 169  ARG 171



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 23/63 (36%), Positives = 37/63 (58%), Gaps = 4/63 (6%)

Query: 2932 EGQVEPKNDPDLKIEWYFNG-KVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYN 2990
            E  V  +++P  K+ W+ NG +V     ++K TS     TL++  +  +D+GIYTC+A N
Sbjct: 112  ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTCRAEN 168

Query: 2991 KRG 2993
             RG
Sbjct: 169  ARG 171



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 6/67 (8%)

Query: 1739 DPKLRVEWLRNG--VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVT 1796
            +PK +V W +NG  VP++      T  D     L +  + P+D+G YTCRA N  G    
Sbjct: 120  NPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTW 175

Query: 1797 SSTLFVQ 1803
            + TL VQ
Sbjct: 176  NITLVVQ 182



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/57 (43%), Positives = 30/57 (52%), Gaps = 12/57 (21%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYV-----ALDIIDLIAEDSGIYTCRAVNLVGTD 1528
            KV WFKNG  V       P+ D  Y       L+I  L+ +D+GIYTCRA N  G D
Sbjct: 124  KVTWFKNGYRV-------PLDDIKYKQTSADTLEIAGLVPQDTGIYTCRAENARGHD 173



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 12/180 (6%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+ V    D+  T  +   F C   G P P V+W  N +    D + +I V +SG  AL 
Sbjct: 3   PRIVSEPTDQVATIHQNITFVCDTQGVPKPRVSWQ-NSQGRPADRDPRITVLQSG--ALH 59

Query: 452 ITNVTLSDSGVVTC-VARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           I        GV T  V    +G         ++ ++       + R +  N+        
Sbjct: 60  IRG------GVPTPRVTWQHNGRNLQYMTPRLVIRDARPQDAGLYRCTGTNLAGRASAET 113

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           +      P P++TW K+G  + P  +++ +    A TL+I      D   Y C A+N  G
Sbjct: 114 SVTVRSNPKPKVTWFKNGYRV-PLDDIK-YKQTSADTLEIAGLVPQDTGIYTCRAENARG 171



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 652 GKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTC 711
           G+   ET +    +P  K+ W KNG  +          +    +L++  L  QD+G YTC
Sbjct: 107 GRASAETSVTVRSNPKPKVTWFKNGYRVPLDD--IKYKQTSADTLEIAGLVPQDTGIYTC 164

Query: 712 RAVSATG 718
           RA +A G
Sbjct: 165 RAENARG 171



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 4/71 (5%)

Query: 3850 ECRVEPKEDPKLRIEWYRNGKLLPSGH-RYRTVYDMGFVSLDILYVYAEDSGEYICRAVN 3908
            E  V  + +PK ++ W++NG  +P    +Y+        +L+I  +  +D+G Y CRA N
Sbjct: 112  ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAEN 168

Query: 3909 DFGEDFTKATI 3919
              G D    T+
Sbjct: 169  ARGHDTWNITL 179



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 6/63 (9%)

Query: 3590 RVEWFHNGK--PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
            +V WF NG   PL      +T  D     LEI G+  +D G+YTC+A N  G  T +  L
Sbjct: 124  KVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTCRAENARGHDTWNITL 179

Query: 3648 QVK 3650
             V+
Sbjct: 180  VVQ 182



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 5/69 (7%)

Query: 415 VTGRPYPEVTWFINDRQIR-DDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGE 473
           V   P P+VTWF N  ++  DD  +K    ++    L I  +   D+G+ TC A N  G 
Sbjct: 117 VRSNPKPKVTWFKNGYRVPLDDIKYK----QTSADTLEIAGLVPQDTGIYTCRAENARGH 172

Query: 474 TAFQCRLNV 482
             +   L V
Sbjct: 173 DTWNITLVV 181



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 6/78 (7%)

Query: 3438 AHFEARLTPTDDPNLKVEWYWNGKSLKAGS-RFR-TFCDFGFVILEISPTYPEDSGEYLC 3495
            A  E  +T   +P  KV W+ NG  +     +++ T  D     LEI+   P+D+G Y C
Sbjct: 109  ASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTC 164

Query: 3496 RAYNNYGEAVTTASMKVQ 3513
            RA N  G      ++ VQ
Sbjct: 165  RAENARGHDTWNITLVVQ 182



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 1854 TKLSEGQSAHYECRIEPYPDPNMRVEWYFNG-KVLQSGHRYR-TSNDFGFAALDILTVYG 1911
            T L+   SA     +   P P  +V W+ NG +V     +Y+ TS D     L+I  +  
Sbjct: 103  TNLAGRASAETSVTVRSNPKP--KVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVP 156

Query: 1912 EDSGEYTCKAINNLGQAVSSIRLNVQ 1937
            +D+G YTC+A N  G    +I L VQ
Sbjct: 157  QDTGIYTCRAENARGHDTWNITLVVQ 182



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 48/181 (26%), Positives = 66/181 (36%), Gaps = 18/181 (9%)

Query: 4425 HEQARFEVEFDGEPLPLIKWYR-ENFPIKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAA 4483
            H+   F  +  G P P + W   +  P    P     T      L IR         +  
Sbjct: 17   HQNITFVCDTQGVPKPRVSWQNSQGRPADRDPRI---TVLQSGALHIRGGVPTPRVTWQ- 72

Query: 4484 VAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPI 4543
               N       +  LV+ + R Q   G+   + T  A   +  +   VR     +  KP 
Sbjct: 73   --HNGRNLQYMTPRLVIRDARPQD-AGLYRCTGTNLAGRASAETSVTVR-----SNPKP- 123

Query: 4544 DVYWLKNGKKVQ-PDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECV 4602
             V W KNG +V   DI+ K    D   TL I    PQD+G Y C A N+ G    +   V
Sbjct: 124  KVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTCRAENARGHDTWNITLV 180

Query: 4603 V 4603
            V
Sbjct: 181  V 181



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 3/95 (3%)

Query: 1042 KPRFLGPLKGTNKIVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYV 1101
            +P+  G  + T   + G+ A  E  V  +S+    V W+ NG ++   + I+ Y      
Sbjct: 91   RPQDAGLYRCTGTNLAGR-ASAETSVTVRSNPKPKVTWFKNGYRVP-LDDIK-YKQTSAD 147

Query: 1102 ALDIASVRAEDSGVYTVVARNAAGEAQLSASMTVE 1136
             L+IA +  +D+G+YT  A NA G    + ++ V+
Sbjct: 148  TLEIAGLVPQDTGIYTCRAENARGHDTWNITLVVQ 182



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 4/67 (5%)

Query: 1594 RAHFERRLIPVSDATLKVEWYHNNKPLKSGS-RFTETNNFGFVALDIMSCLPEDSGTYTC 1652
            RA  E  +   S+   KV W+ N   +     ++ +T+      L+I   +P+D+G YTC
Sbjct: 108  RASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSAD---TLEIAGLVPQDTGIYTC 164

Query: 1653 RAINALG 1659
            RA NA G
Sbjct: 165  RAENARG 171



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 6/75 (8%)

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQ--PMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVC 3224
            A  E +V    +P  K+ W+ NG   P+      +T +D     L+IA     D+G Y C
Sbjct: 109  ASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQTSAD----TLEIAGLVPQDTGIYTC 164

Query: 3225 RAYNKYGEDFTRATI 3239
            RA N  G D    T+
Sbjct: 165  RAENARGHDTWNITL 179



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 5/48 (10%)

Query: 4568 TYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQ 4615
            T  L+I +A PQD+G Y C   N AG A  +    V     +  PKP+
Sbjct: 82   TPRLVIRDARPQDAGLYRCTGTNLAGRASAETSVTV-----RSNPKPK 124



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 19/110 (17%)

Query: 1969 QDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVND---------PTMRVEWYCNGRP 2019
            Q+ +FV +     KP  + + ++G P   +  +T +           PT RV W  NGR 
Sbjct: 18   QNITFVCDTQGVPKPRVSWQNSQGRPADRDPRITVLQSGALHIRGGVPTPRVTWQHNGRN 77

Query: 2020 VQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV 2069
            +Q    + T        L I  A  +D G Y C  TN  G A   +SV V
Sbjct: 78   LQ----YMTP------RLVIRDARPQDAGLYRCTGTNLAGRASAETSVTV 117



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 4/77 (5%)

Query: 2126 RAHFECRVEPINDPHLTIDWFHNGQKIRAGH-RYRTTHDFGYVALDILYTYAEDSGTYMC 2184
            RA  E  V   ++P   + WF NG ++     +Y+ T       L+I     +D+G Y C
Sbjct: 108  RASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTC 164

Query: 2185 KATNKLGEAVNTCTLKV 2201
            +A N  G      TL V
Sbjct: 165  RAENARGHDTWNITLVV 181



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 8/61 (13%)

Query: 95  LRGNPTPVVSWTRK--KAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQY 152
           +R NP P V+W +   + PL +     ++Y + + D +L I  + P D G YTC A N  
Sbjct: 117 VRSNPKPKVTWFKNGYRVPLDD-----IKYKQTSAD-TLEIAGLVPQDTGIYTCRAENAR 170

Query: 153 G 153
           G
Sbjct: 171 G 171



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 4/63 (6%)

Query: 1998 EATLTPVNDPTMRVEWYCNGRPVQQGH-RFKTTYDFGYVALDILYAYAEDTGTYMCKATN 2056
            E ++T  ++P  +V W+ NG  V     ++K T       L+I     +DTG Y C+A N
Sbjct: 112  ETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCRAEN 168

Query: 2057 AVG 2059
            A G
Sbjct: 169  ARG 171



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 2/60 (3%)

Query: 1343 RVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            +V WF NG  +            D   L++  + P+D+G+YTC+A N  G    +  L V
Sbjct: 124  KVTWFKNGYRVPLDDIKYKQTSAD--TLEIAGLVPQDTGIYTCRAENARGHDTWNITLVV 181



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 4/66 (6%)

Query: 2526 AHYEARVVPVGDPSLRFEWYINGVELKMGS-RFRTTHDFGFVTLDINSVVANDAGLYMCK 2584
            A  E  V    +P  +  W+ NG  + +   +++ T      TL+I  +V  D G+Y C+
Sbjct: 109  ASAETSVTVRSNPKPKVTWFKNGYRVPLDDIKYKQT---SADTLEIAGLVPQDTGIYTCR 165

Query: 2585 AINRAG 2590
            A N  G
Sbjct: 166  AENARG 171


>SB_26664| Best HMM Match : I-set (HMM E-Value=7.6e-06)
          Length = 434

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 49/187 (26%), Positives = 74/187 (39%), Gaps = 19/187 (10%)

Query: 3039 QPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIR 3098
            +P +    PP    +F   + I E ++A        TG  + V++W     T+       
Sbjct: 211  KPGETGSAPPRMKPIFAGPIFIKERRLARLP-KCEATGFPTPVLKWLKVYGTLPQGRAFV 269

Query: 3099 TVYAFGMVVLEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNI 3158
               +     L I  T+  DSG Y CRA+N  G  E+  +L          P F    Q+ 
Sbjct: 270  RDDS-----LLISSTRKADSGMYICRASNDLGVTEVFTQLVV-----AALPEFDIRPQDN 319

Query: 3159 EGLKDGQSAHFECTVVPVDDPDMKIEWYH-NGQPMRHSTRIKTVSDFGFVVLDIAYTQNH 3217
              L  G      C+   V DP +++ W   +G+  R      TV D+G +V  I    + 
Sbjct: 320  TTLYTGDIFRANCS--GVGDPTLRVTWKKIDGKLPRFRA---TVRDWGELV--ITQVTSE 372

Query: 3218 DSGEYVC 3224
            DSG Y C
Sbjct: 373  DSGRYAC 379



 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/85 (35%), Positives = 40/85 (47%), Gaps = 8/85 (9%)

Query: 1705 EVITQAPVFTMPMKDIRVAENQAAH----FEARLIPVGDPKLRVEWLRNGVPIEASNRLT 1760
            EV TQ  V  +P  DIR  +N   +    F A    VGDP LRV W +  +  +      
Sbjct: 299  EVFTQLVVAALPEFDIRPQDNTTLYTGDIFRANCSGVGDPTLRVTWKK--IDGKLPRFRA 356

Query: 1761 TMHDFGYVALNMKYVNPEDSGTYTC 1785
            T+ D+G + +    V  EDSG Y C
Sbjct: 357  TVRDWGELVITQ--VTSEDSGRYAC 379



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 56/240 (23%), Positives = 93/240 (38%), Gaps = 24/240 (10%)

Query: 4403 GPVKPSKPPIFTKKMQPCRVFEHEQARF-EVEFDGEPLPLIKWYRENFPIKNSPDFQIHT 4461
            G   P   PIF     P  + E   AR  + E  G P P++KW +    +      Q   
Sbjct: 216  GSAPPRMKPIFAG---PIFIKERRLARLPKCEATGFPTPVLKWLKVYGTLP-----QGRA 267

Query: 4462 FSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQ 4521
            F     L+I      DS ++   A N  G  +    LVV             P F +  Q
Sbjct: 268  FVRDDSLLISSTRKADSGMYICRASNDLGVTEVFTQLVVAAL----------PEFDIRPQ 317

Query: 4522 -NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQD 4580
             N  + +G + R +    G   + V W K   K+ P  R  + +      L+I +   +D
Sbjct: 318  DNTTLYTGDIFRANCSGVGDPTLRVTWKKIDGKL-PRFRATVRDWG---ELVITQVTSED 373

Query: 4581 SGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAI 4640
            SG+Y C+     G  + +A   +++  ++   K    A   PP  I+ +     ++G+A+
Sbjct: 374  SGRYACLLSTDGGIFKNEAFTTLNVINSEYNYKSHIIATITPPLSIQSVHCFRRSQGRAV 433



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 43/171 (25%), Positives = 68/171 (39%), Gaps = 19/171 (11%)

Query: 403 VTEGKMTRFD-CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSG 461
           + E ++ R   C  TG P P + W      +      +  V +    +L+I++   +DSG
Sbjct: 232 IKERRLARLPKCEATGFPTPVLKWLKVYGTLPQG---RAFVRDD---SLLISSTRKADSG 285

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKF-VERFSTLNVREGEPVVLNARAVGTPTP 520
           +  C A N  G T    +L V        P+F +       +  G+    N   VG PT 
Sbjct: 286 MYICRASNDLGVTEVFTQLVV-----AALPEFDIRPQDNTTLYTGDIFRANCSGVGDPTL 340

Query: 521 RITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           R+TW+K DG   +P     +   G    L I +  + D+  Y C      G
Sbjct: 341 RVTWKKIDGK--LPRFRATVRDWG---ELVITQVTSEDSGRYACLLSTDGG 386



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 39/135 (28%), Positives = 57/135 (42%), Gaps = 18/135 (13%)

Query: 3800 PQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            P+G  G+K    + G    AP     +   P FI + +   + + E   F   V      
Sbjct: 199  PRGAKGDKGDRGKPGETGSAPPRMKPIFAGPIFIKERRLARLPKCEATGFPTPV------ 252

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG--EDFTKA 3917
               ++W +    LP G  +  V D    SL I      DSG YICRA ND G  E FT+ 
Sbjct: 253  ---LKWLKVYGTLPQGRAF--VRDD---SLLISSTRKADSGMYICRASNDLGVTEVFTQL 304

Query: 3918 TISCKKLPDIILQNQ 3932
             ++   LP+  ++ Q
Sbjct: 305  VVAA--LPEFDIRPQ 317



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 8/84 (9%)

Query: 3282 PKFITQIQDVTKLVEGQSAHFEARLVPVDDPDLKVEWFYNGKKLPHGHRYR-TFHDFGIV 3340
            P+F  + QD T L  G    F A    V DP L+V W     KLP   R+R T  D+G +
Sbjct: 310  PEFDIRPQDNTTLYTGDI--FRANCSGVGDPTLRVTWKKIDGKLP---RFRATVRDWGEL 364

Query: 3341 ILDILYCYEENSGEYECVATNKLG 3364
            +  I     E+SG Y C+ +   G
Sbjct: 365  V--ITQVTSEDSGRYACLLSTDGG 386



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 8/77 (10%)

Query: 909 PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLK-DGRPVEASSRITTFFNFGYV 967
           PEF    +D  ++  G    F A    +GD TLRV W K DG+     +   T  ++G  
Sbjct: 310 PEFDIRPQDNTTLYTGDI--FRANCSGVGDPTLRVTWKKIDGKLPRFRA---TVRDWG-- 362

Query: 968 ALTIKSVTVHDAGHYTC 984
            L I  VT  D+G Y C
Sbjct: 363 ELVITQVTSEDSGRYAC 379



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 3825 IVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYR-TVYD 3883
            +V+  P+F  + + +T   +  + F        DP LR+ W +    LP   R+R TV D
Sbjct: 305  VVAALPEFDIRPQDNTTLYTGDI-FRANCSGVGDPTLRVTWKKIDGKLP---RFRATVRD 360

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFG 3911
             G   L I  V +EDSG Y C    D G
Sbjct: 361  WG--ELVITQVTSEDSGRYACLLSTDGG 386



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 5/88 (5%)

Query: 637 PQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGYISL 696
           P+F +  +  T +  G I F      VGDPT+++ W K    +    RF +  R  +  L
Sbjct: 310 PEFDIRPQDNTTLYTGDI-FRANCSGVGDPTLRVTWKKIDGKL---PRFRATVR-DWGEL 364

Query: 697 DMLSLNIQDSGEYTCRAVSATGVAETKA 724
            +  +  +DSG Y C   +  G+ + +A
Sbjct: 365 VITQVTSEDSGRYACLLSTDGGIFKNEA 392



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 49/202 (24%), Positives = 81/202 (40%), Gaps = 22/202 (10%)

Query: 4610 DKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEF--SCKIVGKPLPTVQWYKGDKLIKPSK 4667
            D+ KP  +  +APP +       I  + + +     C+  G P P ++W K    +   +
Sbjct: 208  DRGKPG-ETGSAPPRMKPIFAGPIFIKERRLARLPKCEATGFPTPVLKWLKVYGTLPQGR 266

Query: 4668 YFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPL 4727
             F      D+ +L IS     D G Y C A N  G   V  +L V    + D    + P 
Sbjct: 267  AF----VRDD-SLLISSTRKADSGMYICRASNDLGVTEVFTQLVVAALPEFD----IRPQ 317

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQ--WLR-EGALIPETPDFQMIHEGNNAVLLIGNTY 4784
             +  +Y G    F+   +    PT++  W + +G L    P F+     +   L+I    
Sbjct: 318  DNTTLYTGD--IFRANCSGVGDPTLRVTWKKIDGKL----PRFRATVR-DWGELVITQVT 370

Query: 4785 EEDTGTFTCRATTAAGQVETSA 4806
             ED+G + C  +T  G  +  A
Sbjct: 371  SEDSGRYACLLSTDGGIFKNEA 392



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 5/70 (7%)

Query: 4741 KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAG 4800
            K + T    P ++WL+    +P+   F  + + +   LLI +T + D+G + CRA+   G
Sbjct: 242  KCEATGFPTPVLKWLKVYGTLPQGRAF--VRDDS---LLISSTRKADSGMYICRASNDLG 296

Query: 4801 QVETSAKLVV 4810
              E   +LVV
Sbjct: 297  VTEVFTQLVV 306



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 11/94 (11%)

Query: 64  GRPGEP--SPPIFEQIFKNARFAQGGNAKFEGKLR--GNPTPVVSWTRKKAPLVECNKYS 119
           G+PGE   +PP  + IF    F +        K    G PTPV+ W +    L +   + 
Sbjct: 210 GKPGETGSAPPRMKPIFAGPIFIKERRLARLPKCEATGFPTPVLKWLKVYGTLPQGRAF- 268

Query: 120 MRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
                   D SLLI      D G Y C A N  G
Sbjct: 269 ------VRDDSLLISSTRKADSGMYICRASNDLG 296



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            R +P+F  P+     I+E + A    +    G PT  ++W +    +       +     
Sbjct: 221  RMKPIFAGPIF----IKERRLARLP-KCEATGFPTPVLKWLKVYGTLPQGRAFVRDD--- 272

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
              S+ IS  R  D G+Y+CRASN LG
Sbjct: 273  --SLLISSTRKADSGMYICRASNDLG 296



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 8/90 (8%)

Query: 3973 PRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEW-FFNGKPLLHKNRFTPIYDFGYV 4031
            P F  + Q  T+L   +  +  C  + VGDP ++V W   +GK  L + R T + D+G +
Sbjct: 310  PEFDIRPQDNTTLYTGDIFRANC--SGVGDPTLRVTWKKIDGK--LPRFRAT-VRDWGEL 364

Query: 4032 AMNFGWVYPEDSGEYLCRATNLYGMDETKA 4061
             +    V  EDSG Y C  +   G+ + +A
Sbjct: 365  VIT--QVTSEDSGRYACLLSTDGGIFKNEA 392



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F +  +DN  +  G     +C    VGDPT+R+ W              T+ D+G   
Sbjct: 310  PEFDIRPQDNTTLYTGDIFRANC--SGVGDPTLRVTWKKIDGKLPRFRA--TVRDWG--E 363

Query: 3755 LDIDYIYARDAGEYTCRATNKWG 3777
            L I  + + D+G Y C  +   G
Sbjct: 364  LVITQVTSEDSGRYACLLSTDGG 386



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 4/63 (6%)

Query: 2793 FECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATN 2852
            F  N     DPTL++ W   +  LP   R+++T    +  L IT    EDSG Y C  + 
Sbjct: 328  FRANCSGVGDPTLRVTWKKIDGKLP---RFRATVR-DWGELVITQVTSEDSGRYACLLST 383

Query: 2853 SKG 2855
              G
Sbjct: 384  DGG 386



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 2528 YEARVVPVGDPSLRFEWYINGVELKMGSRFR-TTHDFGFVTLDINSVVANDAGLYMC 2583
            + A    VGDP+LR  W    ++ K+  RFR T  D+G   L I  V + D+G Y C
Sbjct: 328  FRANCSGVGDPTLRVTW--KKIDGKL-PRFRATVRDWG--ELVITQVTSEDSGRYAC 379


>SB_24434| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1194

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 11/175 (6%)

Query: 4538 TGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC 4597
            TG    ++ W  N      D  N    +     L+I  A    +G Y C     A  AR 
Sbjct: 205  TGNPVPEIVWFDNHNNEIADGTNGYRFQSHGRVLVIDRADESSAGAYTC-----ACRART 259

Query: 4598 DAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWY 4657
             ++ V         P   T  A   PE+     D +    QA + S  I  + L T +WY
Sbjct: 260  SSKAVAHTKVVIKGPPVLT--ATPKPEVKLMRGDDLALVCQAKQTSEDISHQSLITFEWY 317

Query: 4658 KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            + ++ +  S    +    D+  LR+      D G Y+CVA ++ G  T A+++ +
Sbjct: 318  RNNQQLADSDKIAI----DDGNLRVKNVSDRDNGVYQCVARDNMGMSTAASRVMI 368



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 47/231 (20%), Positives = 92/231 (39%), Gaps = 15/231 (6%)

Query: 4591 SAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLKDKIVAEGQAIEFSCKIVGK 4649
            S G+   D+  +++        K Q+   +A  E++E P   ++   G   E  C   G 
Sbjct: 150  SVGDEYFDSHTMLTSDHGSKTTKEQSVLRDA--ELMEKPATLEVALRGARKELRCIPTGN 207

Query: 4650 PLPTVQWY--KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVA-YNSAGRVTV 4706
            P+P + W+    +++   +  ++    +    L I  A     G Y C     ++ +   
Sbjct: 208  PVPEIVWFDNHNNEIADGTNGYRFQ--SHGRVLVIDRADESSAGAYTCACRARTSSKAVA 265

Query: 4707 AAKLKVTQPD--QADNLPALTPLR-DIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPE 4763
              K+ +  P    A   P +  +R D +    Q  Q    I+ +   T +W R    + +
Sbjct: 266  HTKVVIKGPPVLTATPKPEVKLMRGDDLALVCQAKQTSEDISHQSLITFEWYRNNQQLAD 325

Query: 4764 TPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVKSKT 4814
            + D   I +GN   L + N  + D G + C A    G    ++++++K  T
Sbjct: 326  S-DKIAIDDGN---LRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIKGVT 372



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 52/229 (22%), Positives = 98/229 (42%), Gaps = 32/229 (13%)

Query: 267 KIAQKPRNSKLQ-EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           ++ +KP   ++   GA  + +   +GNP P + WF N    I    +      +   L +
Sbjct: 181 ELMEKPATLEVALRGARKELRCIPTGNPVPEIVWFDNHNNEIADGTNGYRFQSHGRVLVI 240

Query: 326 RNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYVQDQRSQYITDTQQRETEERIEI 385
               +S +G YT        C   +   AV     + V  +    +T T + E +  +  
Sbjct: 241 DRADESSAGAYTC------ACRARTSSKAV---AHTKVVIKGPPVLTATPKPEVK-LMRG 290

Query: 386 SEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNES 445
            + AL      VCQ +  +E         ++ +      W+ N++Q+ D  + KI +++ 
Sbjct: 291 DDLAL------VCQAKQTSED--------ISHQSLITFEWYRNNQQLAD--SDKIAIDD- 333

Query: 446 GNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNV--IEKEQVVAPK 492
           GN  L + NV+  D+GV  CVAR+  G +    R+ +  +    ++AP+
Sbjct: 334 GN--LRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIKGVTCSAILAPR 380



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 43/183 (23%), Positives = 70/183 (38%), Gaps = 21/183 (11%)

Query: 406 GKMTRFDCRVTGRPYPEVTWFIN-DRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           G      C  TG P PE+ WF N + +I D  N      +S    L+I     S +G  T
Sbjct: 195 GARKELRCIPTGNPVPEIVWFDNHNNEIADGTNGYRF--QSHGRVLVIDRADESSAGAYT 252

Query: 465 CVARNKSGETAFQCRLNVIEKEQVV--APKFVERFSTLNVREGEPVVLNARAVGTPTP-- 520
           C  R ++   A      VI+   V+   PK       + +  G+ + L  +A  T     
Sbjct: 253 CACRARTSSKAVAHTKVVIKGPPVLTATPK-----PEVKLMRGDDLALVCQAKQTSEDIS 307

Query: 521 -----RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATR 575
                   W ++   +  + ++ I  DG    L +      D   YQC A++  G +   
Sbjct: 308 HQSLITFEWYRNNQQLADSDKIAI-DDG---NLRVKNVSDRDNGVYQCVARDNMGMSTAA 363

Query: 576 ARL 578
           +R+
Sbjct: 364 SRV 366



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 10/101 (9%)

Query: 3557 PPEFTTTPS-DLILSENSSAHFECRLIPVND-----SSMRVEWFHNGKPLLTGSRVKTIN 3610
            PP  T TP  ++ L         C+    ++     S +  EW+ N + L    ++  I+
Sbjct: 274  PPVLTATPKPEVKLMRGDDLALVCQAKQTSEDISHQSLITFEWYRNNQQLADSDKI-AID 332

Query: 3611 DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            D     L +  V  RD G+Y C A +  G +T + ++ +KG
Sbjct: 333  DGN---LRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIKG 370



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 4/48 (8%)

Query: 2411 EWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
            EW+RN + + DS +I    D G  ++ + +V D D GVY C A + +G
Sbjct: 315  EWYRNNQQLADSDKIAI--DDG--NLRVKNVSDRDNGVYQCVARDNMG 358



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/103 (21%), Positives = 48/103 (46%), Gaps = 9/103 (8%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPN-----LKIEWFKNGVTLTTGARLK 2692
            ++  P+ T   K   KL+ G  + L  Q +  ++       +  EW++N   L    ++ 
Sbjct: 271  IKGPPVLTATPKPEVKLMRGDDLALVCQAKQTSEDISHQSLITFEWYRNNQQLADSDKI- 329

Query: 2693 STFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
               D G   L + ++ + D+G+Y C A + +G + + + + I+
Sbjct: 330  -AIDDG--NLRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIK 369



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 4/62 (6%)

Query: 1075 MTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSGVYTVVARNAAGEAQLSASMT 1134
            +T EWY N +Q+  +++I    D G   L + +V   D+GVY  VAR+  G +  ++ + 
Sbjct: 312  ITFEWYRNNQQLADSDKIAI--DDGN--LRVKNVSDRDNGVYQCVARDNMGMSTAASRVM 367

Query: 1135 VE 1136
            ++
Sbjct: 368  IK 369



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 4/59 (6%)

Query: 2943 LKIEWYFNGKVLEQGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            +  EWY N + L      K+  D G   L + +V +RD+G+Y C A +  G +  +S V
Sbjct: 312  ITFEWYRNNQQLADSD--KIAIDDG--NLRVKNVSDRDNGVYQCVARDNMGMSTAASRV 366



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 299 WFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESP 358
           W++N Q+L +S+K  I    +   LRV+N    D+G Y  +A +  G    +  + ++  
Sbjct: 316 WYRNNQQLADSDKIAI----DDGNLRVKNVSDRDNGVYQCVARDNMGMSTAASRVMIKGV 371

Query: 359 TESYVQDQR-SQY 370
           T S +   R SQ+
Sbjct: 372 TCSAILAPRDSQF 384


>SB_59087| Best HMM Match : ig (HMM E-Value=1.5e-27)
          Length = 955

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 9/99 (9%)

Query: 4623 PEIIEPLKDKIVA--EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            P I  P K +I+    G  +  +C   G P P +QWYK    I+ +    +     E  L
Sbjct: 658  PRISTP-KSQILRLYRGTTLNQTCVSQGNPAPVIQWYK----IEMNGSVSLQTRVKEGRL 712

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
             I E   ED G+Y CVA NS G  + A  L +T+ + A+
Sbjct: 713  LIDEMREEDFGNYSCVATNSRG--SDAVYLSITELESAE 749



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 43/171 (25%), Positives = 61/171 (35%), Gaps = 18/171 (10%)

Query: 413 CRVTGRPYPEVTWFIND---------RQIRDDYNHKILVNESGNHALMITNVTL-SDSGV 462
           C V   P   VTW+            R  R+      L+   G   L+I +    + SG 
Sbjct: 575 CLVNAHPEATVTWWAGSLKLNAITEQRTCRNSLRGYYLLRGRGGDTLVICDALHEAHSGW 634

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
           +TC A N  G       L+++   ++  PK       L +  G  +     + G P P I
Sbjct: 635 LTCTAENHKGTDQRSAYLDILVSPRISTPK----SQILRLYRGTTLNQTCVSQGNPAPVI 690

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
            W K    I  N  + + T      L I   +  D   Y C A N  GS A
Sbjct: 691 QWYK----IEMNGSVSLQTRVKEGRLLIDEMREEDFGNYSCVATNSRGSDA 737



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 36/128 (28%), Positives = 54/128 (42%), Gaps = 18/128 (14%)

Query: 411 FDCRVTGRPYPEVTWFINDRQIRDD---YN---------HKILVNESGNHALMITNVTL- 457
           F C  TG P PE+ WF + +++  D   +N         HK  V++  N  L + +V   
Sbjct: 247 FHCAATGFPLPEIRWFKDGKELLTDNCLWNCKHRRVYEKHKAGVHDV-NECLRVNDVKFP 305

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAV-G 516
            D+GV TC A N     A       +    +V P   +R  ++ V+      L    + G
Sbjct: 306 DDAGVYTCQATN---GVAVLPSTRSVRAVFLVPPVLDKRIGSIVVQSDTTPTLTCTILSG 362

Query: 517 TPTPRITW 524
            P PR TW
Sbjct: 363 YPLPRFTW 370



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 45/214 (21%), Positives = 86/214 (40%), Gaps = 23/214 (10%)

Query: 1192 GKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYT 1251
            G++ ++ C +   G  T+ +EW       ++GS         FV +   H T A      
Sbjct: 139  GESFNITCEVTSAGVSTLNIEW-----QKSIGS--------AFVRIPADH-TFAKKNALV 184

Query: 1252 VRAVNHLGSAHTSAIVRVIERSDIVTDTQNEQAIEQIQLLEDAARRTKQVREDITVMQAP 1311
            +   N    A      + + +  +  D + EQ    + +L+           D  ++ AP
Sbjct: 185  LMFKN--APAMNQTYFKCVAKLSVPKDYKKEQGT-YVHILDPVPATISHFTTDDEIVLAP 241

Query: 1312 QFSRALHNIETVEGTNVHLECRLQPVGDQ--TMRVEWFCNGKPIKTGHRFRPAYEFDYVA 1369
              S+  H   T  G  +  E R    G +  T    W C  + +   H+       + + 
Sbjct: 242  DTSQDFHCAAT--GFPLP-EIRWFKDGKELLTDNCLWNCKHRRVYEKHKAGVHDVNECLR 298

Query: 1370 LDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVI 1403
            ++ +  +P+D+GVYTCQATN +    ++ ++R +
Sbjct: 299  VNDVK-FPDDAGVYTCQATNGVAVLPSTRSVRAV 331



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 13/105 (12%)

Query: 2642 PIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG--------ARLKS 2693
            P   +H  + D++V       +        P  +I WFK+G  L T          R+  
Sbjct: 225  PATISHFTTDDEIVLAPDTSQDFHCAATGFPLPEIRWFKDGKELLTDNCLWNCKHRRVYE 284

Query: 2694 TFDFGL----VTLSINSLR-NDDSGIYTCKATNLLGEAVSTASIK 2733
                G+      L +N ++  DD+G+YTC+ATN +    ST S++
Sbjct: 285  KHKAGVHDVNECLRVNDVKFPDDAGVYTCQATNGVAVLPSTRSVR 329



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 6/58 (10%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           +GNP PV+ W +     +E N  S+    +  +  LLI ++   D G Y+C A N  G
Sbjct: 683 QGNPAPVIQWYK-----IEMNG-SVSLQTRVKEGRLLIDEMREEDFGNYSCVATNSRG 734



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 4/82 (4%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I T K Q  R++            G P P+I+WY+    I+ +    + T   +  L+
Sbjct: 658  PRISTPKSQILRLYRGTTLNQTCVSQGNPAPVIQWYK----IEMNGSVSLQTRVKEGRLL 713

Query: 4470 IRQVFVEDSAVFAAVAENRGGT 4491
            I ++  ED   ++ VA N  G+
Sbjct: 714  IDEMREEDFGNYSCVATNSRGS 735



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 7/53 (13%)

Query: 2678 WFKNGVTLTTGARLKSTFDFGL-------VTLSINSLRNDDSGIYTCKATNLL 2723
            W ++GVTLT     + + DF L       V+LS+ +   +DSG+Y+C A  ++
Sbjct: 479  WRRDGVTLTPTEDPRISIDFVLSNALSQEVSLSVANATVNDSGVYSCHADQMI 531


>SB_50854| Best HMM Match : ig (HMM E-Value=6.1e-27)
          Length = 770

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 39/171 (22%), Positives = 69/171 (40%), Gaps = 15/171 (8%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGM-------VVLEILGTKTTDSGTYSCRATN 3127
            TG  +  I W YN  T+          A+ +       + L +      + G Y CRA+N
Sbjct: 247  TGYPAPNITWLYNNMTVRPGRHDMWHGAYYLNALDHRRLTLNLFAVTRDNQGIYMCRASN 306

Query: 3128 KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKD-GQSAHFECTVVPVDDPD-MKIEW 3185
             WG+ E+ + +  +     + P+   +  +   +   G+++   CTV  + + + +   W
Sbjct: 307  GWGKEELVLNVTVI-----ELPKLAVNSDSQFYVSHRGENSTLTCTVTGIRNGETITAHW 361

Query: 3186 YHNGQPMRHSTRIKTVS-DFGFVVLDIAYTQNHDSGEYVCRAYNKYGEDFT 3235
             H     R  TR +T+S     +VL +      D G Y C   +K G   T
Sbjct: 362  RHGSSASRGRTRTQTLSGGRARLVLFLEDVTASDGGSYSCGISSKEGTHAT 412



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 41/172 (23%), Positives = 62/172 (36%), Gaps = 13/172 (7%)

Query: 413 CRVTGRPYPEVTWFINDRQI---RDDYNHKILVNESGNHALMITN---VTLSDSGVVTCV 466
           C VTG P P +TW  N+  +   R D  H      + +H  +  N   VT  + G+  C 
Sbjct: 244 CEVTGYPAPNITWLYNNMTVRPGRHDMWHGAYYLNALDHRRLTLNLFAVTRDNQGIYMCR 303

Query: 467 ARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT---PTPRIT 523
           A N  G+      + VIE  ++      + + +     GE   L     G     T    
Sbjct: 304 ASNGWGKEELVLNVTVIELPKLAVNSDSQFYVS---HRGENSTLTCTVTGIRNGETITAH 360

Query: 524 WQKDGVPIIPNPELRIHTDGGAS-TLDIPRAKASDAAWYQCTAQNVAGSTAT 574
           W+            +  + G A   L +    ASD   Y C   +  G+ AT
Sbjct: 361 WRHGSSASRGRTRTQTLSGGRARLVLFLEDVTASDGGSYSCGISSKEGTHAT 412



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 11/105 (10%)

Query: 1852 GPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR-------YRTSNDFGFAAL 1904
            GP +   G   +  C +  YP PN  + W +N   ++ G         Y  + D     L
Sbjct: 230  GPLRWPLGSRQYLACEVTGYPAPN--ITWLYNNMTVRPGRHDMWHGAYYLNALDHRRLTL 287

Query: 1905 DILTVYGEDSGEYTCKAINNLG--QAVSSIRLNVQSKESIIRDSQ 1947
            ++  V  ++ G Y C+A N  G  + V ++ +    K ++  DSQ
Sbjct: 288  NLFAVTRDNQGIYMCRASNGWGKEELVLNVTVIELPKLAVNSDSQ 332



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 41/206 (19%), Positives = 76/206 (36%), Gaps = 17/206 (8%)

Query: 4619 ANAPPEIIEPLKDKIVAE---GQAIEFSCKIVGKPLPTVQWYKGDKLIKPSK-------Y 4668
            A  PP I  PL          G     +C++ G P P + W   +  ++P +       Y
Sbjct: 216  ARGPPRINIPLTQPGPLRWPLGSRQYLACEVTGYPAPNITWLYNNMTVRPGRHDMWHGAY 275

Query: 4669 FQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLR 4728
            +  +      TL +     +++G Y C A N  G+  +   + V    +   L   +  +
Sbjct: 276  YLNALDHRRLTLNLFAVTRDNQGIYMCRASNGWGKEELVLNVTVI---ELPKLAVNSDSQ 332

Query: 4729 DIVVYEGQPAQFK---TQITSKIKPTIQWLREGALIPETPDFQMIHEGN-NAVLLIGNTY 4784
              V + G+ +      T I +    T  W    +        Q +  G    VL + +  
Sbjct: 333  FYVSHRGENSTLTCTVTGIRNGETITAHWRHGSSASRGRTRTQTLSGGRARLVLFLEDVT 392

Query: 4785 EEDTGTFTCRATTAAGQVETSAKLVV 4810
              D G+++C  ++  G   T+  +VV
Sbjct: 393  ASDGGSYSCGISSKEGTHATTFLVVV 418



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 9/76 (11%)

Query: 2124 GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHR-------YRTTHDFGYVALDILYTYA 2176
            G R +  C V     P++T  W +N   +R G         Y    D   + L++     
Sbjct: 237  GSRQYLACEVTGYPAPNIT--WLYNNMTVRPGRHDMWHGAYYLNALDHRRLTLNLFAVTR 294

Query: 2177 EDSGTYMCKATNKLGE 2192
            ++ G YMC+A+N  G+
Sbjct: 295  DNQGIYMCRASNGWGK 310



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 9/76 (11%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTG-------ARLKSTFDFGLVTLSINSLRN 2709
            G   YL  +V     PN  I W  N +T+  G       A   +  D   +TL++ ++  
Sbjct: 237  GSRQYLACEVTGYPAPN--ITWLYNNMTVRPGRHDMWHGAYYLNALDHRRLTLNLFAVTR 294

Query: 2710 DDSGIYTCKATNLLGE 2725
            D+ GIY C+A+N  G+
Sbjct: 295  DNQGIYMCRASNGWGK 310



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 27/106 (25%), Positives = 40/106 (37%), Gaps = 11/106 (10%)

Query: 3690 EKPNPPRFTVEIKDN--IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSR---- 3743
            E   PPR  + +     +  P G   +  C V   G P   I W +N      G      
Sbjct: 215  EARGPPRINIPLTQPGPLRWPLGSRQYLACEV--TGYPAPNITWLYNNMTVRPGRHDMWH 272

Query: 3744 -VHTLN--DFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKIT 3786
              + LN  D   + L++  +   + G Y CRA+N WG       +T
Sbjct: 273  GAYYLNALDHRRLTLNLFAVTRDNQGIYMCRASNGWGKEELVLNVT 318



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)

Query: 4106 KARCPP---VFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYD 4162
            +AR PP   + ++ P  +    G      C VTG+P P + WL N  T+  G R+ + + 
Sbjct: 215  EARGPPRINIPLTQPGPLRWPLGSRQYLACEVTGYPAPNITWLYNNMTVRPG-RHDMWHG 273

Query: 4163 GMY 4165
              Y
Sbjct: 274  AYY 276



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 4/66 (6%)

Query: 1459 GQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRF-RPIHDFGYVA--LDIIDLIAEDSG 1515
            GQ+V   C +     ++ +++W K+GQ VT G  +       G     L I++  A+D+G
Sbjct: 152  GQNVVLNCTVAAGRRAS-RMDWLKHGQGVTEGVTYCLDARGAGLTCAVLQIVNASAKDAG 210

Query: 1516 IYTCRA 1521
            +Y C A
Sbjct: 211  VYVCEA 216


>SB_33962| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 823

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 9/99 (9%)

Query: 4623 PEIIEPLKDKIVA--EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            P I  P K +I+    G  +  +C   G P P +QWYK    I+ +    +     E  L
Sbjct: 134  PRISTP-KSQILRLYRGTTLNQTCVSQGNPAPVIQWYK----IEMNGSVSLQTRVKEGRL 188

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQAD 4719
             I E   ED G+Y CVA NS G  + A  L +T+ + A+
Sbjct: 189  LIDEMREEDFGNYSCVATNSRG--SDAVYLSITELESAE 225



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 43/171 (25%), Positives = 61/171 (35%), Gaps = 18/171 (10%)

Query: 413 CRVTGRPYPEVTWFIND---------RQIRDDYNHKILVNESGNHALMITNVTL-SDSGV 462
           C V   P   VTW+            R  R+      L+   G   L+I +    + SG 
Sbjct: 51  CLVNAHPEATVTWWAGSLKLNAITEQRTCRNSLRGYYLLRGRGGDTLVICDALHEAHSGW 110

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
           +TC A N  G       L+++   ++  PK       L +  G  +     + G P P I
Sbjct: 111 LTCTAENHKGTDQRSAYLDILVSPRISTPK----SQILRLYRGTTLNQTCVSQGNPAPVI 166

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTA 573
            W K    I  N  + + T      L I   +  D   Y C A N  GS A
Sbjct: 167 QWYK----IEMNGSVSLQTRVKEGRLLIDEMREEDFGNYSCVATNSRGSDA 213



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 6/58 (10%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           +GNP PV+ W +     +E N  S+    +  +  LLI ++   D G Y+C A N  G
Sbjct: 159 QGNPAPVIQWYK-----IEMNG-SVSLQTRVKEGRLLIDEMREEDFGNYSCVATNSRG 210



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 4/82 (4%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFSTKSILI 4469
            P I T K Q  R++            G P P+I+WY+    I+ +    + T   +  L+
Sbjct: 134  PRISTPKSQILRLYRGTTLNQTCVSQGNPAPVIQWYK----IEMNGSVSLQTRVKEGRLL 189

Query: 4470 IRQVFVEDSAVFAAVAENRGGT 4491
            I ++  ED   ++ VA N  G+
Sbjct: 190  IDEMREEDFGNYSCVATNSRGS 211


>SB_27603| Best HMM Match : ig (HMM E-Value=2.9e-10)
          Length = 135

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 5/99 (5%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP I   P N    EG++A       G P P V W K  +   +  +HE+   +    L 
Sbjct: 2   PPTILPLPNNVTYFEGSEAVLTCSAEGTPFPIVYWSKQAK---SHGRHEL--ANRSMNLH 56

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESYV 363
           + N  +   GHYT  A N  G +  + YL V    +S V
Sbjct: 57  LFNISRDHQGHYTCTAYNRAGTVNATLYLYVAPVDQSAV 95



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 7/98 (7%)

Query: 4622 PPEIIEPLKDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            PP I+ PL + +   EG     +C   G P P V W K  K     ++   +R+ + +  
Sbjct: 2    PPTIL-PLPNNVTYFEGSEAVLTCSAEGTPFPIVYWSKQAK--SHGRHELANRSMNLHLF 58

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQA 4718
             IS    + +G Y C AYN AG V     L V   DQ+
Sbjct: 59   NISR---DHQGHYTCTAYNRAGTVNATLYLYVAPVDQS 93



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 23/91 (25%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVS 130
           PP    +  N  + +G  A       G P P+V W+++        K   R+      ++
Sbjct: 2   PPTILPLPNNVTYFEGSEAVLTCSAEGTPFPIVYWSKQA-------KSHGRHELANRSMN 54

Query: 131 LLIKQIGPGDEGEYTCTARNQYGEAICSVYI 161
           L +  I    +G YTCTA N+ G    ++Y+
Sbjct: 55  LHLFNISRDHQGHYTCTAYNRAGTVNATLYL 85



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 6/68 (8%)

Query: 405 EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVT 464
           EG      C   G P+P V W    +Q +    H+ L N S N  L + N++    G  T
Sbjct: 16  EGSEAVLTCSAEGTPFPIVYW---SKQAKSHGRHE-LANRSMN--LHLFNISRDHQGHYT 69

Query: 465 CVARNKSG 472
           C A N++G
Sbjct: 70  CTAYNRAG 77



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 15/35 (42%), Positives = 17/35 (48%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMW 4144
            PP  + LP+ VT  EG  A   C   G P P V W
Sbjct: 2    PPTILPLPNNVTYFEGSEAVLTCSAEGTPFPIVYW 36


>SB_53873| Best HMM Match : Fibrinogen_C (HMM E-Value=0)
          Length = 660

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 48/169 (28%), Positives = 69/169 (40%), Gaps = 19/169 (11%)

Query: 4644 CKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGR 4703
            C+  G P P V W K    +   +      T+D+ TL I +    D G Y C A +  G 
Sbjct: 294  CRATGYPNPVVSWQKVFDKMPEGRTI----TSDQ-TLSILKTRRSDSGLYLCTATSPLGS 348

Query: 4704 VTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQWLR-EGALIP 4762
                  L V    +      + P R I  Y G   +     +++  P I W R +G    
Sbjct: 349  SKSTTHLVVAVRPKF----TVRPPRKIKQYAGATVRVNCSASAEPPPKITWERCQGGT-- 402

Query: 4763 ETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
                 ++I  G + VL   N   EDTGT+TC AT+     +TS  + VK
Sbjct: 403  -----RVIASGESLVLR--NLRYEDTGTYTCTATSRPLLAKTSFVIRVK 444



 Score = 43.6 bits (98), Expect = 0.004
 Identities = 40/130 (30%), Positives = 53/130 (40%), Gaps = 11/130 (8%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I+ V L D G   C   + SG       L V       AP+       +    GE + 
Sbjct: 236 LKISRVRLRDRGTYMCTVDSVSGMARALVTLKVRG-----APRINLDSGPVFAVRGENIT 290

Query: 510 L-NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
           L   RA G P P ++WQK        PE R  T     TL I + + SD+  Y CTA + 
Sbjct: 291 LPRCRATGYPNPVVSWQK---VFDKMPEGRTITSD--QTLSILKTRRSDSGLYLCTATSP 345

Query: 569 AGSTATRARL 578
            GS+ +   L
Sbjct: 346 LGSSKSTTHL 355



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 17/201 (8%)

Query: 4612 PKPQ-TKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
            PK + T + NAP   +EP     V E  A  F+C        T+ W + D  +   K  +
Sbjct: 172  PKEERTGSINAPGIRVEP-SSLTVNENAAATFTCSSTTPGKATIMWSRVDGNMLGRKSIK 230

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDI 4730
            + +      L+IS     D G Y C   + +G       LKV    +  NL +      +
Sbjct: 231  VRQGK----LKISRVRLRDRGTYMCTVDSVSGMARALVTLKVRGAPRI-NLDS----GPV 281

Query: 4731 VVYEGQPAQF-KTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTG 4789
                G+     + + T    P + W +   +  + P+ + I   ++  L I  T   D+G
Sbjct: 282  FAVRGENITLPRCRATGYPNPVVSWQK---VFDKMPEGRTI--TSDQTLSILKTRRSDSG 336

Query: 4790 TFTCRATTAAGQVETSAKLVV 4810
             + C AT+  G  +++  LVV
Sbjct: 337  LYLCTATSPLGSSKSTTHLVV 357



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 34/115 (29%), Positives = 49/115 (42%), Gaps = 12/115 (10%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           CR TG P P V+W    +++ D       +  + +  L I     SDSG+  C A +  G
Sbjct: 294 CRATGYPNPVVSW----QKVFDKMPEGRTI--TSDQTLSILKTRRSDSGLYLCTATSPLG 347

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFST-LNVREGEPVVLNARAVGTPTPRITWQK 526
            +     L V      V PKF  R    +    G  V +N  A   P P+ITW++
Sbjct: 348 SSKSTTHLVV-----AVRPKFTVRPPRKIKQYAGATVRVNCSASAEPPPKITWER 397



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 35/135 (25%), Positives = 53/135 (39%), Gaps = 9/135 (6%)

Query: 3527 GMEGTIDKIAALEGYSGTVDTLTPEAE---SGNPPEFTTTPSDLILSENSSAHFECRLIP 3583
            G+ G++    +  G  G    + P+ E   S N P     PS L ++EN++A F C    
Sbjct: 149  GVGGSVIAQKSDTGDDGKEPIVYPKEERTGSINAPGIRVEPSSLTVNENAAATFTCS--S 206

Query: 3584 VNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATV 3643
                   + W      +L    +K         L+I  V  RD G Y C   +  G A  
Sbjct: 207  TTPGKATIMWSRVDGNMLGRKSIKVRQGK----LKISRVRLRDRGTYMCTVDSVSGMARA 262

Query: 3644 SCKLQVKGRQGIILE 3658
               L+V+G   I L+
Sbjct: 263  LVTLKVRGAPRINLD 277



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 5/66 (7%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            PN  + W K    +  G  + S       TLSI   R  DSG+Y C AT+ LG + ST  
Sbjct: 300  PNPVVSWQKVFDKMPEGRTITSD-----QTLSILKTRRSDSGLYLCTATSPLGSSKSTTH 354

Query: 2732 IKIEDR 2737
            + +  R
Sbjct: 355  LVVAVR 360



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 15/122 (12%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L IL T+ +DSG Y C AT+  G ++ +  L         +P+FT           G + 
Sbjct: 325  LSILKTRRSDSGLYLCTATSPLGSSKSTTHLVV-----AVRPKFTVRPPRKIKQYAGATV 379

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
               C+     +P  KI W    +  +  TR+   S    V+ ++ Y    D+G Y C A 
Sbjct: 380  RVNCSASA--EPPPKITW----ERCQGGTRV-IASGESLVLRNLRY---EDTGTYTCTAT 429

Query: 3228 NK 3229
            ++
Sbjct: 430  SR 431



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 30/87 (34%), Positives = 39/87 (44%), Gaps = 8/87 (9%)

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLEKIRQLEAQGH 2228
            L IL T   DSG Y+C AT+ LG + +T  L VA        T  P    KI+Q    G 
Sbjct: 325  LSILKTRRSDSGLYLCTATSPLGSSKSTTHLVVAVRPKF---TVRPP--RKIKQY--AGA 377

Query: 2229 STRIEVEEPKISPPRFVTE-LRGTTHV 2254
            + R+        PP+   E  +G T V
Sbjct: 378  TVRVNCSASAEPPPKITWERCQGGTRV 404



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 37/112 (33%), Positives = 47/112 (41%), Gaps = 9/112 (8%)

Query: 1826 DSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHY-ECRIEPYPDPNMRVEWYFNG 1884
            DS     R  V + V  APR I   +GP     G++     CR   YP+P   V W    
Sbjct: 254  DSVSGMARALVTLKVRGAPR-INLDSGPVFAVRGENITLPRCRATGYPNPV--VSWQKVF 310

Query: 1885 KVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNV 1936
              +  G R  TS+      L IL     DSG Y C A + LG + S+  L V
Sbjct: 311  DKMPEG-RTITSDQ----TLSILKTRRSDSGLYLCTATSPLGSSKSTTHLVV 357



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 12/80 (15%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTW--FKNGQRLINSNKHEIITTHNH 320
           V P    + PR  K   GA  +     S  P P++TW   + G R+I S +         
Sbjct: 359 VRPKFTVRPPRKIKQYAGATVRVNCSASAEPPPKITWERCQGGTRVIASGE--------- 409

Query: 321 TTLRVRNTQKSDSGHYTLLA 340
            +L +RN +  D+G YT  A
Sbjct: 410 -SLVLRNLRYEDTGTYTCTA 428


>SB_50833| Best HMM Match : Thyroglobulin_1 (HMM E-Value=1.1e-08)
          Length = 280

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 29/87 (33%), Positives = 42/87 (48%), Gaps = 5/87 (5%)

Query: 264 SPPKIAQKPRNSKLQEGADAQFQVQL--SGNPRPRVTWFKNGQRLI---NSNKHEIITTH 318
           +P KI ++   S +   A  Q  ++    G PRP+  W + G++L+   N   H   T H
Sbjct: 17  TPAKINKQKTASTVHTSAGQQAMLKCFYDGIPRPQAIWMREGKQLLECKNCVTHIDNTKH 76

Query: 319 NHTTLRVRNTQKSDSGHYTLLAENPNG 345
             TTLRV   ++SD G Y     N NG
Sbjct: 77  GVTTLRVTPYRESDYGDYICKVRNENG 103



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 5/107 (4%)

Query: 3827 STPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM-- 3884
            +TP K   Q  + TV  S G +   +      P+ +  W R GK L       T  D   
Sbjct: 16   NTPAKINKQKTASTVHTSAGQQAMLKCFYDGIPRPQAIWMREGKQLLECKNCVTHIDNTK 75

Query: 3885 -GFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQ 3930
             G  +L +      D G+YIC+  N+ G  F   TI+  + P ++ Q
Sbjct: 76   HGVTTLRVTPYRESDYGDYICKVRNENG--FDSVTITLVEQPAVMSQ 120



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 3/76 (3%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDG---GASTLDIPRAK 554
           ST++   G+  +L     G P P+  W ++G  ++       H D    G +TL +   +
Sbjct: 28  STVHTSAGQQAMLKCFYDGIPRPQAIWMREGKQLLECKNCVTHIDNTKHGVTTLRVTPYR 87

Query: 555 ASDAAWYQCTAQNVAG 570
            SD   Y C  +N  G
Sbjct: 88  ESDYGDYICKVRNENG 103



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 1/58 (1%)

Query: 97  GNPTPVVSWTRKKAPLVEC-NKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           G P P   W R+   L+EC N  +   N + G  +L +      D G+Y C  RN+ G
Sbjct: 46  GIPRPQAIWMREGKQLLECKNCVTHIDNTKHGVTTLRVTPYRESDYGDYICKVRNENG 103


>SB_48846| Best HMM Match : Pkinase_Tyr (HMM E-Value=8.1e-16)
          Length = 523

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 1/88 (1%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDK-LIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            VA G  +  +C   G PLP V W K  + LI+  +  + S T+   +L +     +D+G 
Sbjct: 7    VARGLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGL 66

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADN 4720
            Y C  +N AG  +    L V   +   N
Sbjct: 67   YVCRGWNLAGMASGNITLMVRVVEAGTN 94



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 1/64 (1%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLV-TLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            P  ++ W KN   L    R++ T +  LV +L +  + +DD G+Y C+  NL G A    
Sbjct: 23   PLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASGNI 82

Query: 2731 SIKI 2734
            ++ +
Sbjct: 83   TLMV 86



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 1/56 (1%)

Query: 2404 GDPTLKVEWFRNEKLIEDSSRITKTHDFGYV-SMTISHVRDEDEGVYMCRASNLLG 2458
            G P  +V W +N + +    R+ +T +   V S+ +  V  +D+G+Y+CR  NL G
Sbjct: 21   GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAG 76



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 3590 RVEWFHNGKPLLTGSRVKTINDFGFVI-LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQ 3648
            RV W  N + L+   RV+  ++   V  LE+ GV   D GLY C+  N  G A+ +  L 
Sbjct: 26   RVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASGNITLM 85

Query: 3649 VK 3650
            V+
Sbjct: 86   VR 87



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 1/74 (1%)

Query: 498 STLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGG-ASTLDIPRAKAS 556
           S + V  G  V L     G+P PR+TW K+   +I    +R  ++    ++L++    + 
Sbjct: 3   SLMTVARGLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSD 62

Query: 557 DAAWYQCTAQNVAG 570
           D   Y C   N+AG
Sbjct: 63  DDGLYVCRGWNLAG 76



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 4/97 (4%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFV-TLDINSVVANDAGLYMCKAINRAGXXXX 2594
            G P  R  W  N  EL    R R T +   V +L++  V ++D GLY+C+  N AG    
Sbjct: 21   GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASG 80

Query: 2595 XXXXXXXXXXXIIDQAM---RPESWEQIQLKEAAMNK 2628
                         +  +   R + W  +  +  AMNK
Sbjct: 81   NITLMVRVVEAGTNTTLVLTRKQGWGSVVFRVWAMNK 117



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)

Query: 280 GADAQFQVQLSGNPRPRVTWFKNGQRLINSNK-HEIITTHNHTTLRVRNTQKSDSGHYTL 338
           G D       +G+P PRVTW KN + LI   +  E   T    +L ++     D G Y  
Sbjct: 10  GLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVC 69

Query: 339 LAENPNG 345
              N  G
Sbjct: 70  RGWNLAG 76



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 4/88 (4%)

Query: 1317 LHNIETV-EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVA-LDLLS 1374
            ++++ TV  G +V L C     G    RV W  N + +    R R   E   VA L+L  
Sbjct: 1    MNSLMTVARGLDVSLTCLF--TGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQG 58

Query: 1375 VYPEDSGVYTCQATNQLGEAVTSCALRV 1402
            V  +D G+Y C+  N  G A  +  L V
Sbjct: 59   VSSDDDGLYVCRGWNLAGMASGNITLMV 86



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVA-LNMKYVNPEDSGTYTCRAINELGEAVT 1796
            G P  RV W +N   +    R+    +   VA L ++ V+ +D G Y CR  N  G A  
Sbjct: 21   GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASG 80

Query: 1797 SSTLFVQ 1803
            + TL V+
Sbjct: 81   NITLMVR 87



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 1850 LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGK-VLQSGHRYRTSNDFGFAALDILT 1908
            +N    ++ G      C     P P  RV W  N + +++ G    TS     A+L++  
Sbjct: 1    MNSLMTVARGLDVSLTCLFTGSPLP--RVTWSKNSRELIRQGRVRETSETSLVASLELQG 58

Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            V  +D G Y C+  N  G A  +I L V+  E+
Sbjct: 59   VSSDDDGLYVCRGWNLAGMASGNITLMVRVVEA 91



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 5/86 (5%)

Query: 1189 VSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA-LDIIHATSADT 1247
            V+ G ++ L C     G P  RV W  N R +    R +   +   VA L++   +S D 
Sbjct: 7    VARGLDVSLTCLFT--GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDD 64

Query: 1248 GEYTVRAVNHLG--SAHTSAIVRVIE 1271
            G Y  R  N  G  S + + +VRV+E
Sbjct: 65   GLYVCRGWNLAGMASGNITLMVRVVE 90



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%)

Query: 1452 SIENVIEGQHVHFECKLEPVTDSNL-KVEWFKNGQPVTIGHRFRPIHDFGYVA-LDIIDL 1509
            S+  V  G  V   C     T S L +V W KN + +    R R   +   VA L++  +
Sbjct: 3    SLMTVARGLDVSLTCLF---TGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGV 59

Query: 1510 IAEDSGIYTCRAVNLVG 1526
             ++D G+Y CR  NL G
Sbjct: 60   SSDDDGLYVCRGWNLAG 76



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA-LDIDYIYARDAGEYTCRATNKWGSAT 3780
            G P  R+ W  N R      RV   ++   +A L++  + + D G Y CR  N  G A+
Sbjct: 21   GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMAS 79



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVA-MNFGWVYPEDSGEYLCRATNLYGM 4056
            G P  +V W  N + L+ + R     +   VA +    V  +D G Y+CR  NL GM
Sbjct: 21   GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGM 77



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 1986 NAEVTEGHPVHLEATLTPVNDPTMRVEWYCNGRPVQQGHRFKTTYDFGYVA-LDILYAYA 2044
            N+ +T    + +  T      P  RV W  N R + +  R + T +   VA L++    +
Sbjct: 2    NSLMTVARGLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSS 61

Query: 2045 EDTGTYMCKATNAVGEA 2061
            +D G Y+C+  N  G A
Sbjct: 62   DDDGLYVCRGWNLAGMA 78



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 4/102 (3%)

Query: 3447 TDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI-LEISPTYPEDSGEYLCRAYNNYGEA- 3504
            T  P  +V W  N + L    R R   +   V  LE+     +D G Y+CR +N  G A 
Sbjct: 20   TGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMAS 79

Query: 3505 --VTTASMKVQGKRNIILESQLPKGMEGTIDKIAALEGYSGT 3544
              +T     V+   N  L     +G    + ++ A+  Y  +
Sbjct: 80   GNITLMVRVVEAGTNTTLVLTRKQGWGSVVFRVWAMNKYGSS 121



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 2803 PTLKIEWFFNNKPLPSGTRYKSTHDFSYV-SLDITHTYEEDSGIYTCKATNSKGSAT 2858
            P  ++ W  N++ L    R + T + S V SL++     +D G+Y C+  N  G A+
Sbjct: 23   PLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMAS 79



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 1/59 (1%)

Query: 2944 KIEWYFNGKVLEQGSRFKLTSDFGFV-TLDLVDVYERDSGIYTCKAYNKRGEAFTSSTV 3001
            ++ W  N + L +  R + TS+   V +L+L  V   D G+Y C+ +N  G A  + T+
Sbjct: 26   RVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASGNITL 84



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 1/53 (1%)

Query: 1610 KVEWYHNNKPLKSGSRFTETNNFGFVA-LDIMSCLPEDSGTYTCRAINALGEA 1661
            +V W  N++ L    R  ET+    VA L++     +D G Y CR  N  G A
Sbjct: 26   RVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMA 78



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 20/70 (28%), Positives = 28/70 (40%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V  G      C  TG P P VTW  N R++      +     S   +L +  V+  D G+
Sbjct: 7   VARGLDVSLTCLFTGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGL 66

Query: 463 VTCVARNKSG 472
             C   N +G
Sbjct: 67  YVCRGWNLAG 76



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 1/65 (1%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV-LEILGTKTTDSGTYSCRATNKWGQAE 3133
            TG     + W  N + +    R+R      +V  LE+ G  + D G Y CR  N  G A 
Sbjct: 20   TGSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMAS 79

Query: 3134 ISVKL 3138
             ++ L
Sbjct: 80   GNITL 84



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 17/66 (25%), Positives = 28/66 (42%), Gaps = 1/66 (1%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYI-SLDMLSLNIQDSGEYTCRAVSATGVAET 722
           G P  ++ W KN + +    R         + SL++  ++  D G Y CR  +  G+A  
Sbjct: 21  GSPLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASG 80

Query: 723 KAVLHV 728
              L V
Sbjct: 81  NITLMV 86



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 2143 IDWFHNGQKIRAGHRYRTTHDFGYVA-LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            + W  N +++    R R T +   VA L++    ++D G Y+C+  N  G A    TL V
Sbjct: 27   VTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAGMASGNITLMV 86



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 3179 PDMKIEWYHNGQPMRHSTRIKTVSDFGFVV-LDIAYTQNHDSGEYVCRAYNKYG 3231
            P  ++ W  N + +    R++  S+   V  L++    + D G YVCR +N  G
Sbjct: 23   PLPRVTWSKNSRELIRQGRVRETSETSLVASLELQGVSSDDDGLYVCRGWNLAG 76


>SB_994| Best HMM Match : I-set (HMM E-Value=6e-15)
          Length = 189

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 3/97 (3%)

Query: 2106 GQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFH-NGQKIRAGHRYRTTHDF 2164
            G   V L     + N    DR   EC+V    + HL   W   NGQ I +  R+  ++  
Sbjct: 76   GSPKVVLVNTPRVRNAVVDDRVEIECQVTSNPEAHLY--WISDNGQVITSSGRFLVSNRN 133

Query: 2165 GYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
                L I Y  A DSG Y C A N +G +  T  + V
Sbjct: 134  CNPTLTISYLLASDSGNYSCVANNSVGSSRQTVKIIV 170



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 1/81 (1%)

Query: 4524 NVTSGQLVRLDTKVTGTKPIDVYWLK-NGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            N      V ++ +VT      +YW+  NG+ +    R  +   +   TL I      DSG
Sbjct: 90   NAVVDDRVEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSG 149

Query: 4583 KYECVAINSAGEARCDAECVV 4603
             Y CVA NS G +R   + +V
Sbjct: 150  NYSCVANNSVGSSRQTVKIIV 170



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            +E  C++   P   + W   + ++I  S  F +S      TL IS     D G+Y CVA 
Sbjct: 97   VEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVAN 156

Query: 4699 NSAG--RVTVAAKLKVTQPDQADN 4720
            NS G  R TV   +K  + D   N
Sbjct: 157  NSVGSSRQTVKIIVKAVKFDHPPN 180



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 20/74 (27%), Positives = 34/74 (45%)

Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
           R+         +C+VT  P   + W  ++ Q+       ++ N + N  L I+ +  SDS
Sbjct: 89  RNAVVDDRVEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDS 148

Query: 461 GVVTCVARNKSGET 474
           G  +CVA N  G +
Sbjct: 149 GNYSCVANNSVGSS 162



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)

Query: 3713 VHFDCRVEPVGDPTMRIDWFH-NGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCR 3771
            V  +C+V    +P   + W   NG+   +  R    N      L I Y+ A D+G Y+C 
Sbjct: 97   VEIECQV--TSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCV 154

Query: 3772 ATNKWGSATTTAKITCSA 3789
            A N  GS+  T KI   A
Sbjct: 155  ANNSVGSSRQTVKIIVKA 172



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 3/75 (4%)

Query: 1865 ECRIEPYPDPNMRVEWYF-NGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAIN 1923
            EC++   P+ ++   W   NG+V+ S  R+  SN      L I  +   DSG Y+C A N
Sbjct: 100  ECQVTSNPEAHLY--WISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANN 157

Query: 1924 NLGQAVSSIRLNVQS 1938
            ++G +  ++++ V++
Sbjct: 158  SVGSSRQTVKIIVKA 172



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 4/93 (4%)

Query: 1447 VTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFK-NGQPVTIGHRFRPIHDFGYVALD 1505
            V  P+ + N +    V  EC++    +++L   W   NGQ +T   RF   +      L 
Sbjct: 83   VNTPR-VRNAVVDDRVEIECQVTSNPEAHLY--WISDNGQVITSSGRFLVSNRNCNPTLT 139

Query: 1506 IIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRS 1538
            I  L+A DSG Y+C A N VG+   + ++  ++
Sbjct: 140  ISYLLASDSGNYSCVANNSVGSSRQTVKIIVKA 172



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 5/89 (5%)

Query: 1984 IKNAEVTEGHPVHLEATLTPVNDPTMRVEWYC-NGRPVQQGHRFKTTYDFGYVALDILYA 2042
            ++NA V +   V +E  +T  ++P   + W   NG+ +    RF  +       L I Y 
Sbjct: 88   VRNAVVDDR--VEIECQVT--SNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYL 143

Query: 2043 YAEDTGTYMCKATNAVGEAVTTSSVKVDA 2071
             A D+G Y C A N+VG +  T  + V A
Sbjct: 144  LASDSGNYSCVANNSVGSSRQTVKIIVKA 172



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 4739 QFKTQITSKIKPTIQWLRE-GALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
            + + Q+TS  +  + W+ + G +I  +  F + +   N  L I      D+G ++C A  
Sbjct: 98   EIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANN 157

Query: 4798 AAGQVETSAKLVVKS 4812
            + G    + K++VK+
Sbjct: 158  SVGSSRQTVKIIVKA 172



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 17/63 (26%), Positives = 34/63 (53%), Gaps = 1/63 (1%)

Query: 284 QFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHN-HTTLRVRNTQKSDSGHYTLLAEN 342
           + + Q++ NP   + W  +  ++I S+   +++  N + TL +     SDSG+Y+ +A N
Sbjct: 98  EIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANN 157

Query: 343 PNG 345
             G
Sbjct: 158 SVG 160



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 10/102 (9%)

Query: 3811 LERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NG 3869
            L++ +I     +  +V+TP     ++++  V++   V  EC+V    +P+  + W   NG
Sbjct: 68   LQKSKIFAGSPKVVLVNTP-----RVRNAVVDDR--VEIECQVT--SNPEAHLYWISDNG 118

Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
            +++ S  R+         +L I Y+ A DSG Y C A N  G
Sbjct: 119  QVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANNSVG 160



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)

Query: 2789 DNIHFECNVEPSRDPTLKIEWFFNN-KPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            D +  EC V  + +P   + W  +N + + S  R+  ++     +L I++    DSG Y+
Sbjct: 95   DRVEIECQV--TSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYS 152

Query: 2848 CKATNSKGSA 2857
            C A NS GS+
Sbjct: 153  CVANNSVGSS 162



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 1/75 (1%)

Query: 2662 LEAQVEPRTDPNLKIEWFK-NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKAT 2720
            +E + +  ++P   + W   NG  +T+  R   +      TL+I+ L   DSG Y+C A 
Sbjct: 97   VEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVAN 156

Query: 2721 NLLGEAVSTASIKIE 2735
            N +G +  T  I ++
Sbjct: 157  NSVGSSRQTVKIIVK 171



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 5/83 (6%)

Query: 1059 QSAHFEARVEPQSDLTMTVEWYF-----NGKQITSANRIQTYHDFGYVALDIASVRAEDS 1113
            ++A  + RVE +  +T   E +      NG+ ITS+ R    +      L I+ + A DS
Sbjct: 89   RNAVVDDRVEIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDS 148

Query: 1114 GVYTVVARNAAGEAQLSASMTVE 1136
            G Y+ VA N+ G ++ +  + V+
Sbjct: 149  GNYSCVANNSVGSSRQTVKIIVK 171



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 1/74 (1%)

Query: 2263 ECQVEPVHDPNLRIEFYHNGKALQSAARFHITFDFGYVSLDIQHCVPEDAGEYSVKAINA 2322
            ECQV    + +L      NG+ + S+ RF ++      +L I + +  D+G YS  A N+
Sbjct: 100  ECQVTSNPEAHL-YWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANNS 158

Query: 2323 LGHCTSAISMTVTA 2336
            +G     + + V A
Sbjct: 159  VGSSRQTVKIIVKA 172



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 1/67 (1%)

Query: 1739 DPKLRVEWLR-NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            +P+  + W+  NG  I +S R    +      L + Y+   DSG Y+C A N +G +  +
Sbjct: 106  NPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANNSVGSSRQT 165

Query: 1798 STLFVQS 1804
              + V++
Sbjct: 166  VKIIVKA 172



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/130 (22%), Positives = 47/130 (36%), Gaps = 6/130 (4%)

Query: 3239 INCYGKGGVYLESLQPDSLAKIRELESLQGAQQ---QTPSTPSAEPPKFITQIQDVTKLV 3295
            + CYG    +L S+   S   ++   S  G      Q     +  P   +     V   V
Sbjct: 33   LRCYGMNTCFLPSITAQSSYFLQAQCSYLGLYSGSLQKSKIFAGSPKVVLVNTPRVRNAV 92

Query: 3296 EGQSAHFEARLVPVDDPDLKVEWFY-NGKKLPHGHRYRTFHDFGIVILDILYCYEENSGE 3354
                   E ++    +P+  + W   NG+ +    R+   +      L I Y    +SG 
Sbjct: 93   VDDRVEIECQVT--SNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGN 150

Query: 3355 YECVATNKLG 3364
            Y CVA N +G
Sbjct: 151  YSCVANNSVG 160



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%)

Query: 657 ETRIEPVGDPTMKIEWLK-NGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVS 715
           E   +   +P   + W+  NGQ I +S RF    R    +L +  L   DSG Y+C A +
Sbjct: 98  EIECQVTSNPEAHLYWISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANN 157

Query: 716 ATG 718
           + G
Sbjct: 158 SVG 160



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 16/62 (25%), Positives = 30/62 (48%), Gaps = 1/62 (1%)

Query: 945  WLKD-GRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVT 1003
            W+ D G+ + +S R           LTI  +   D+G+Y+C A N++G +  +  + +  
Sbjct: 113  WISDNGQVITSSGRFLVSNRNCNPTLTISYLLASDSGNYSCVANNSVGSSRQTVKIIVKA 172

Query: 1004 KK 1005
             K
Sbjct: 173  VK 174


>SB_56444| Best HMM Match : fn3 (HMM E-Value=1.2e-21)
          Length = 651

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 55/225 (24%), Positives = 91/225 (40%), Gaps = 25/225 (11%)

Query: 1840 VNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDF 1899
            +  AP FI+ L     ++E  +    C     P PN  V WY          RY+ +N  
Sbjct: 222  IRGAPSFISSLRSFYHVTENTNISVTCLASGRPAPN--VTWYTKTS------RYQLANGI 273

Query: 1900 GFAALDILTVYGEDSGEYTCKAINNLGQ--AVSSIRLNVQSKESIIRDSQHESALEKIQY 1957
            G A L +  +    SG Y C+AIN++ +    + I +NVQ    ++R       + K + 
Sbjct: 274  GSATLSLSKIQRNQSGVYECRAINDVRRPPITTKITINVQ----LVRHLGF--VVLKPKA 327

Query: 1958 LEDDSRYKRAVQDDSFVVEKPQFGKPIKNAEVTEGHPVHLEATLTPVNDPTMRVEWY-CN 2016
              + S     +   S   +KP+     +N     G  + L+ T      P   + WY  +
Sbjct: 328  PANLSPCCLVLFRSS---DKPEMLDSTQNTSSWNGRLLSLQCTAR--GSPYPYITWYKPD 382

Query: 2017 GRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEA 2061
            G+ ++ G     +   G +       Y  D G Y C+A+N +G A
Sbjct: 383  GQLIKVG---ACSIKDGSLLQIRTTQYTGDYGEYKCRASNLIGSA 424



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 51/207 (24%), Positives = 84/207 (40%), Gaps = 28/207 (13%)

Query: 4514 PSFTLTAQNV-NVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PSF  + ++  +VT    + +    +G    +V W     + Q  + N I    G+ TL 
Sbjct: 226  PSFISSLRSFYHVTENTNISVTCLASGRPAPNVTWYTKTSRYQ--LANGI----GSATLS 279

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP----KPQTKAANAP------ 4622
            + +     SG YEC AIN         +  +++   +       KP+  A  +P      
Sbjct: 280  LSKIQRNQSGVYECRAINDVRRPPITTKITINVQLVRHLGFVVLKPKAPANLSPCCLVLF 339

Query: 4623 -----PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGD-KLIKPSKYFQMSRTAD 4676
                 PE+++  ++     G+ +   C   G P P + WYK D +LIK           D
Sbjct: 340  RSSDKPEMLDSTQNTSSWNGRLLSLQCTARGSPYPYITWYKPDGQLIKVG----ACSIKD 395

Query: 4677 EYTLRI-SEAFPEDEGDYKCVAYNSAG 4702
               L+I +  +  D G+YKC A N  G
Sbjct: 396  GSLLQIRTTQYTGDYGEYKCRASNLIG 422



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 8/97 (8%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++ AP F + L+S+  + E  ++ +      R  PN  + W+      T  +R +     
Sbjct: 222  IRGAPSFISSLRSFYHVTENTNISVTCLASGRPAPN--VTWY------TKTSRYQLANGI 273

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            G  TLS++ ++ + SG+Y C+A N +     T  I I
Sbjct: 274  GSATLSLSKIQRNQSGVYECRAINDVRRPPITTKITI 310



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%)

Query: 391 APQFVKVCQD-RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           AP F+   +    VTE       C  +GRP P VTW+    + +       L N  G+  
Sbjct: 225 APSFISSLRSFYHVTENTNISVTCLASGRPAPNVTWYTKTSRYQ-------LANGIGSAT 277

Query: 450 LMITNVTLSDSGVVTCVARN 469
           L ++ +  + SGV  C A N
Sbjct: 278 LSLSKIQRNQSGVYECRAIN 297



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 49/218 (22%), Positives = 77/218 (35%), Gaps = 22/218 (10%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIA 3754
            P F   ++    V E   +   C     G P   + W+         SR    N  G   
Sbjct: 226  PSFISSLRSFYHVTENTNISVTCLAS--GRPAPNVTWY------TKTSRYQLANGIGSAT 277

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKELERG 3814
            L +  I    +G Y CRA N       T KIT +         QL + +    +K     
Sbjct: 278  LSLSKIQRNQSGVYECRAINDVRRPPITTKITINV--------QLVRHLGFVVLKPKAPA 329

Query: 3815 RISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYR-NGKLLP 3873
             +S         S  P+ +   ++ +      +  +C    +  P   I WY+ +G+L+ 
Sbjct: 330  NLSPCCLVLFRSSDKPEMLDSTQNTSSWNGRLLSLQCTA--RGSPYPYITWYKPDGQLIK 387

Query: 3874 SGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
             G    ++ D   + +     Y  D GEY CRA N  G
Sbjct: 388  VGAC--SIKDGSLLQIRTTQ-YTGDYGEYKCRASNLIG 422



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 14/114 (12%)

Query: 3830 PKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            P FI+ ++S + V E+  +   C    +  P   + WY          RY+    +G  +
Sbjct: 226  PSFISSLRSFYHVTENTNISVTCLASGRPAPN--VTWYTKTS------RYQLANGIGSAT 277

Query: 3889 LDILYVYAEDSGEYICRAVNDFGED--FTKATIS---CKKLPDIILQNQVPRGM 3937
            L +  +    SG Y CRA+ND       TK TI+    + L  ++L+ + P  +
Sbjct: 278  LSLSKIQRNQSGVYECRAINDVRRPPITTKITINVQLVRHLGFVVLKPKAPANL 331



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 49/192 (25%), Positives = 71/192 (36%), Gaps = 20/192 (10%)

Query: 2536 GDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVANDAGLYMCKAINRAGXXXXX 2595
            G P+    WY         SR++  +  G  TL ++ +  N +G+Y C+AIN        
Sbjct: 252  GRPAPNVTWYTKT------SRYQLANGIGSATLSLSKIQRNQSGVYECRAIN------DV 299

Query: 2596 XXXXXXXXXXIIDQAMRPESWEQIQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLV 2655
                      I  Q +R   +  ++ K A  N  P   V       P     L S     
Sbjct: 300  RRPPITTKITINVQLVRHLGFVVLKPK-APANLSPCCLVLFRSSDKP---EMLDSTQNTS 355

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFK-NGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGI 2714
                  L  Q   R  P   I W+K +G  +  GA   S  D  L+ +        D G 
Sbjct: 356  SWNGRLLSLQCTARGSPYPYITWYKPDGQLIKVGA--CSIKDGSLLQIRTTQY-TGDYGE 412

Query: 2715 YTCKATNLLGEA 2726
            Y C+A+NL+G A
Sbjct: 413  YKCRASNLIGSA 424



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P++    +N+    G     Q    G+P P +TW+K   +LI   K    +  + + L++
Sbjct: 345 PEMLDSTQNTSSWNGRLLSLQCTARGSPYPYITWYKPDGQLI---KVGACSIKDGSLLQI 401

Query: 326 RNTQ-KSDSGHYTLLAEN 342
           R TQ   D G Y   A N
Sbjct: 402 RTTQYTGDYGEYKCRASN 419



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 4/66 (6%)

Query: 96  RGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGEA 155
           RG+P P ++W +    L++    S++     G +  +      GD GEY C A N  G A
Sbjct: 369 RGSPYPYITWYKPDGQLIKVGACSIK----DGSLLQIRTTQYTGDYGEYKCRASNLIGSA 424

Query: 156 ICSVYI 161
              +++
Sbjct: 425 EAVIHV 430



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 26/112 (23%), Positives = 50/112 (44%), Gaps = 10/112 (8%)

Query: 1426 DTSRYKKTDIIDESVTIK--PRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKN 1483
            D + Y+ T +   ++ I+  P F++  +S  +V E  ++   C        N  V W+  
Sbjct: 206  DPTSYRFTALRVWNLKIRGAPSFISSLRSFYHVTENTNISVTCLASGRPAPN--VTWY-- 261

Query: 1484 GQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLT 1535
                T   R++  +  G   L +  +    SG+Y CRA+N V    ++ ++T
Sbjct: 262  ----TKTSRYQLANGIGSATLSLSKIQRNQSGVYECRAINDVRRPPITTKIT 309



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 12/41 (29%), Positives = 20/41 (48%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQI 432
           P+ +   Q+     G++    C   G PYP +TW+  D Q+
Sbjct: 345 PEMLDSTQNTSSWNGRLLSLQCTARGSPYPYITWYKPDGQL 385



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 8/83 (9%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            R  P F   L++  ++ E       C  +  G P   V W+        +SR    +  G
Sbjct: 223  RGAPSFISSLRSFYHVTENTNISVTC--LASGRPAPNVTWYTK------TSRYQLANGIG 274

Query: 2433 YVSMTISHVRDEDEGVYMCRASN 2455
              ++++S ++    GVY CRA N
Sbjct: 275  SATLSLSKIQRNQSGVYECRAIN 297



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 2958 SRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYN 2990
            SR++L +  G  TL L  +    SG+Y C+A N
Sbjct: 265  SRYQLANGIGSATLSLSKIQRNQSGVYECRAIN 297



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 10/112 (8%)

Query: 1282 EQAIEQIQLLEDAARRTKQVRE-DITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGD 1339
            ++ +  + +++  + R   +R  ++ +  AP F  +L +   V E TN+ + C     G 
Sbjct: 196  DEKVYLVAIMDPTSYRFTALRVWNLKIRGAPSFISSLRSFYHVTENTNISVTCLAS--GR 253

Query: 1340 QTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQL 1391
                V W+      KT  R++ A       L L  +    SGVY C+A N +
Sbjct: 254  PAPNVTWYT-----KTS-RYQLANGIGSATLSLSKIQRNQSGVYECRAINDV 299


>SB_29125| Best HMM Match : I-set (HMM E-Value=1.8e-09)
          Length = 108

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 4639 AIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAY 4698
            ++   C   G P+P++ W +   LI+PSK  ++  +    TL I      D G Y+CVA 
Sbjct: 37   SVSIHCNATGNPVPSITWSRSGALIEPSKRIKIMGS----TLVIVGTLWSDTGSYECVAS 92

Query: 4699 NSAGRVTVAAKLK 4711
            N AG    ++ LK
Sbjct: 93   NGAGTDRKSSFLK 105



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 5/83 (6%)

Query: 4515 SFTLT-AQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            S  LT   N+N      V +    TG     + W ++G  ++P  R KI+      TL+I
Sbjct: 21   SHALTIGDNLNTLISTSVSIHCNATGNPVPSITWSRSGALIEPSKRIKIMGS----TLVI 76

Query: 4574 LEAYPQDSGKYECVAINSAGEAR 4596
            +     D+G YECVA N AG  R
Sbjct: 77   VGTLWSDTGSYECVASNGAGTDR 99



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 4/72 (5%)

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
           LN      V ++  A G P P ITW + G  I P+  ++I      STL I     SD  
Sbjct: 30  LNTLISTSVSIHCNATGNPVPSITWSRSGALIEPSKRIKIM----GSTLVIVGTLWSDTG 85

Query: 560 WYQCTAQNVAGS 571
            Y+C A N AG+
Sbjct: 86  SYECVASNGAGT 97



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 5/60 (8%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  TG P P +TW  +   I      KI+        L+I     SD+G   CVA N +G
Sbjct: 42  CNATGNPVPSITWSRSGALIEPSKRIKIM-----GSTLVIVGTLWSDTGSYECVASNGAG 96



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 4/64 (6%)

Query: 290 SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
           +GNP P +TW ++G  +  S + +I+     +TL +  T  SD+G Y  +A N  G    
Sbjct: 45  TGNPVPSITWSRSGALIEPSKRIKIM----GSTLVIVGTLWSDTGSYECVASNGAGTDRK 100

Query: 350 SGYL 353
           S +L
Sbjct: 101 SSFL 104



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 3075 TGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTYSCRATNKWG 3130
            TG+    I W  +G  IE S RI+ + +     L I+GT  +D+G+Y C A+N  G
Sbjct: 45   TGNPVPSITWSRSGALIEPSKRIKIMGS----TLVIVGTLWSDTGSYECVASNGAG 96



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 4/59 (6%)

Query: 4750 PTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKL 4808
            P+I W R GALI  +   +++     + L+I  T   DTG++ C A+  AG    S+ L
Sbjct: 50   PSITWSRSGALIEPSKRIKIM----GSTLVIVGTLWSDTGSYECVASNGAGTDRKSSFL 104


>SB_53160| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 292

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 8/116 (6%)

Query: 2619 IQLKEAAMNKVPEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEW 2678
            ++++ ++    P    D  V+ AP FT+ L S   + E   V +      R  PN  I W
Sbjct: 146  VKIRTSSSPLSPSASWDLNVKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPN--ITW 203

Query: 2679 FKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
                V  T+G+ +      G  TLS+  ++   +G+Y C+A N +G    T +I I
Sbjct: 204  ----VNKTSGSPV--AHGTGSATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITI 253



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 10/104 (9%)

Query: 1837 EVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTS 1896
            ++ V  AP F + L+    ++E       C     P PN  + W    K   S   + T 
Sbjct: 162  DLNVKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPN--ITWV--NKTSGSPVAHGT- 216

Query: 1897 NDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQS 1938
               G A L +L +    +G Y C+AIN++G+     +I +NVQS
Sbjct: 217  ---GSATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITINVQS 257



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 11/88 (12%)

Query: 489 VAPKFVERFSTL-NVREGEPVVLNARAVGTPTPRITW--QKDGVPIIPNPELRIHTDGGA 545
           VAP F    S+  +V E + V +   A G P P ITW  +  G P+        H  G A
Sbjct: 167 VAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNITWVNKTSGSPV-------AHGTGSA 219

Query: 546 STLDIPRAKASDAAWYQCTAQNVAGSTA 573
            TL + + +   A  YQC A N  G  A
Sbjct: 220 -TLSLLKIQRHQAGVYQCQAINDVGRGA 246



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 31/108 (28%), Positives = 41/108 (37%), Gaps = 12/108 (11%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRPFATGSRVHTLNDFGF 3752
            P FT  +  + DV E   V   C     G P   I W +  +G P A G+        G 
Sbjct: 169  PAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNITWVNKTSGSPVAHGT--------GS 218

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLP 3800
              L +  I    AG Y C+A N  G    T  IT + +       +LP
Sbjct: 219  ATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITINVQSIFRSSCKLP 266



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 27/110 (24%), Positives = 45/110 (40%), Gaps = 9/110 (8%)

Query: 1437 DESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPI 1496
            D +V + P F +   S  +V E   V   C        N+      +G PV         
Sbjct: 162  DLNVKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNITWVNKTSGSPVA-------- 213

Query: 1497 HDFGYVALDIIDLIAEDSGIYTCRAVNLVGTDEVSCRLTCRSTTDIVRST 1546
            H  G   L ++ +    +G+Y C+A+N VG   ++  +T  +   I RS+
Sbjct: 214  HGTGSATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITI-NVQSIFRSS 262



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 8/87 (9%)

Query: 390 LAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           +AP F   +   RDV E       C  +GRP P +TW +N        +   + + +G+ 
Sbjct: 167 VAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNITW-VNKT------SGSPVAHGTGSA 219

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETA 475
            L +  +    +GV  C A N  G  A
Sbjct: 220 TLSLLKIQRHQAGVYQCQAINDVGRGA 246



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 33/152 (21%), Positives = 54/152 (35%), Gaps = 13/152 (8%)

Query: 2307 CVPEDAGEYSVKAINALGHCTSAISMTVTAKGSIISESQRPEGLEKIRELESAEPFKRPE 2366
            C P D        +   G  TS   +      S++ E      L KIR   S+ P     
Sbjct: 105  CAPNDTDTIYKGRLYFYGDFTSCSGVVEIRNASVVDEKSY---LVKIRT--SSSPLSPSA 159

Query: 2367 IPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRIT 2426
              +   +  P FT  L +  ++ E       C     G P   + W      +  +S   
Sbjct: 160  SWDLNVKVAPAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNITW------VNKTSGSP 211

Query: 2427 KTHDFGYVSMTISHVRDEDEGVYMCRASNLLG 2458
              H  G  ++++  ++    GVY C+A N +G
Sbjct: 212  VAHGTGSATLSLLKIQRHQAGVYQCQAINDVG 243



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 13/102 (12%)

Query: 1304 DITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGDQTMRVEWF--CNGKPIKTGHRFR 1360
            D+ V  AP F+ +L +   V E  +V + C     G     + W    +G P+       
Sbjct: 162  DLNVKVAPAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNITWVNKTSGSPV------- 212

Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRV 1402
             A+      L LL +    +GVY CQA N +G    + A+ +
Sbjct: 213  -AHGTGSATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITI 253



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 15/100 (15%)

Query: 1710 APVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR--NGVPIEASNRLTTMHDFG 1766
            AP FT  +   R VAEN            G P   + W+   +G P+         H  G
Sbjct: 168  APAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNITWVNKTSGSPVA--------HGTG 217

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQS 1804
               L++  +    +G Y C+AIN++G  A+T + T+ VQS
Sbjct: 218  SATLSLLKIQRHQAGVYQCQAINDVGRGAITQAITINVQS 257



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 9/87 (10%)

Query: 3826 VSTPPKFITQIKS-HTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDM 3884
            V   P F + + S   V E++ V   C    +  P   I W       P  H        
Sbjct: 165  VKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPN--ITWVNKTSGSPVAH------GT 216

Query: 3885 GFVSLDILYVYAEDSGEYICRAVNDFG 3911
            G  +L +L +    +G Y C+A+ND G
Sbjct: 217  GSATLSLLKIQRHQAGVYQCQAINDVG 243


>SB_51910| Best HMM Match : ig (HMM E-Value=4.9e-05)
          Length = 562

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 40/129 (31%), Positives = 54/129 (41%), Gaps = 6/129 (4%)

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK-GDKLIKPSKYFQMSRTADEYTLRISEAF 4686
            P+K  I     A+   C   G P P V W K G  L + S    +   + +Y  +I E  
Sbjct: 419  PMKQYIQYNTTALVQGCNAQGTPSPVVTWTKNGVPLDRYSVMVPVRPHSTQY--QIPEVQ 476

Query: 4687 PEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPAL-TPLRDIVVYEGQPAQFKTQIT 4745
              DEG+Y C  Y   G V +  K+  TQ    D LP+      D    EG+ A F    T
Sbjct: 477  KSDEGNYTCSVYQHMGYVDMVFKVS-TQLVVYD-LPSFRREPSDQTRREGEDAVFNCVAT 534

Query: 4746 SKIKPTIQW 4754
               KP ++W
Sbjct: 535  GIPKPHLEW 543



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 34/114 (29%), Positives = 43/114 (37%), Gaps = 7/114 (6%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C   G P P VTW  N   + D Y+  + V         I  V  SD G  TC      G
Sbjct: 435 CNAQGTPSPVVTWTKNGVPL-DRYSVMVPVRPHSTQ-YQIPEVQKSDEGNYTCSVYQHMG 492

Query: 473 --ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
             +  F+    ++  +    P F    S    REGE  V N  A G P P + W
Sbjct: 493 YVDMVFKVSTQLVVYD---LPSFRREPSDQTRREGEDAVFNCVATGIPKPHLEW 543



 Score = 42.7 bits (96), Expect = 0.007
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 10/89 (11%)

Query: 66  PGEPSPPIFEQI-FKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNE 124
           P   S P+ + I +      QG NA+      G P+PVV+WT+   PL   ++YS+    
Sbjct: 413 PHSGSLPMKQYIQYNTTALVQGCNAQ------GTPSPVVTWTKNGVPL---DRYSVMVPV 463

Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           +       I ++   DEG YTC+     G
Sbjct: 464 RPHSTQYQIPEVQKSDEGNYTCSVYQHMG 492



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/129 (23%), Positives = 53/129 (41%), Gaps = 7/129 (5%)

Query: 442 VNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLN 501
           V  S +H+L +    +SD+G+         G      +  V      +  K   +++T  
Sbjct: 371 VRISADHSLEMNAAKISDAGIYMFHGSQNVGYFTVYIKALVFPHSGSLPMKQYIQYNTTA 430

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           + +G        A GTP+P +TW K+GVP +    + +     ++   IP  + SD   Y
Sbjct: 431 LVQG------CNAQGTPSPVVTWTKNGVP-LDRYSVMVPVRPHSTQYQIPEVQKSDEGNY 483

Query: 562 QCTAQNVAG 570
            C+     G
Sbjct: 484 TCSVYQHMG 492



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 2/73 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQ-VQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P     P    +Q    A  Q     G P P VTW KNG  L   +    +  H+ T  +
Sbjct: 413 PHSGSLPMKQYIQYNTTALVQGCNAQGTPSPVVTWTKNGVPLDRYSVMVPVRPHS-TQYQ 471

Query: 325 VRNTQKSDSGHYT 337
           +   QKSD G+YT
Sbjct: 472 IPEVQKSDEGNYT 484



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 12/133 (9%)

Query: 1668 IVHSKKSIYLESQHEGALPRLNQLEDTSKYQRHSAQD----EVITQAPVF----TMPMKD 1719
            IV   K + + + H   +    ++ D   Y  H +Q+     V  +A VF    ++PMK 
Sbjct: 364  IVEKDKEVRISADHSLEM-NAAKISDAGIYMFHGSQNVGYFTVYIKALVFPHSGSLPMKQ 422

Query: 1720 IRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPED 1779
              +  N  A  +      G P   V W +NGVP++  + +  +         +  V   D
Sbjct: 423  Y-IQYNTTALVQG-CNAQGTPSPVVTWTKNGVPLDRYSVMVPVRPHS-TQYQIPEVQKSD 479

Query: 1780 SGTYTCRAINELG 1792
             G YTC     +G
Sbjct: 480  EGNYTCSVYQHMG 492


>SB_39770| Best HMM Match : TolA (HMM E-Value=0.33)
          Length = 732

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 41/170 (24%), Positives = 80/170 (47%), Gaps = 12/170 (7%)

Query: 4232 EKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKL-QELENEQVI 4290
            E T EE  +LQ +G  D   +L+  + +E E E  ++  RK+ EE  + + +ELE EQ  
Sbjct: 277  EDTLEEEAMLQ-EGKQDALRKLRQTIQREREEE--EAALRKEKEEALDAVREELEEEQEE 333

Query: 4291 KESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDP 4350
            KESRLR+   Q        +   + +S+A+ +E    + EE     + ++  +  +  D 
Sbjct: 334  KESRLRDEKEQ--------SLRKLRESLAREHEKEKRKIEEEYHAALDEQREKLDKEKDA 385

Query: 4351 SESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERV 4400
                +  K  +  +QK+T+     +K +   +T  +  +     +T+ ++
Sbjct: 386  EIEKLQQKNQYELQQKKTELIEKHEKAMEDVLTELDQVQNAELGETKRKM 435


>SB_13504| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 4924

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 52/196 (26%), Positives = 76/196 (38%), Gaps = 34/196 (17%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            P  F  T     V  G+ V L  +      +   W +  + VQ         + GT  L 
Sbjct: 4229 PRLFNQTISRWTVEEGEHVVLGCEAQSVTKVIYTWRRGDEVVQK-------ADHGTLELP 4281

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDK 4632
             ++    ++G Y C A N  G A    E ++         KP+         + EP+  K
Sbjct: 4282 SIKR--SEAGMYTCEAANHKGSAEYHYEIIIEY-------KPEL--------LEEPISFK 4324

Query: 4633 IVAEG-QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPED-- 4689
            +   G +   FSC   G P P V+WY      +P  Y ++S    +   R+    P+D  
Sbjct: 4325 LALYGGKGATFSCLATGNPQPRVEWY-----YRP-LYSKLSFKLPDNDSRLVYIEPDDVM 4378

Query: 4690 -EGDYKCVAYNSAGRV 4704
              G Y CVA NS GRV
Sbjct: 4379 RSGFYYCVASNSRGRV 4394



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 25/130 (19%), Positives = 53/130 (40%), Gaps = 6/130 (4%)

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
            +V ++ +  L + ++  S++G+ TC A N  G   +   + +  K +++      + +  
Sbjct: 4269 VVQKADHGTLELPSIKRSEAGMYTCEAANHKGSAEYHYEIIIEYKPELLEEPISFKLALY 4328

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
                G+    +  A G P PR+ W     P+      ++  D  +  + I       + +
Sbjct: 4329 G---GKGATFSCLATGNPQPRVEWYYR--PLYSKLSFKL-PDNDSRLVYIEPDDVMRSGF 4382

Query: 561  YQCTAQNVAG 570
            Y C A N  G
Sbjct: 4383 YYCVASNSRG 4392



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 9/124 (7%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            LE+   K +++G Y+C A N  G AE   ++    K +  +   +  +     L  G+ A
Sbjct: 4278 LELPSIKRSEAGMYTCEAANHKGSAEYHYEIIIEYKPELLEEPISFKL----ALYGGKGA 4333

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             F C  +   +P  ++EWY+  +P+      K + D    ++ I       SG Y C A 
Sbjct: 4334 TFSC--LATGNPQPRVEWYY--RPLYSKLSFK-LPDNDSRLVYIEPDDVMRSGFYYCVAS 4388

Query: 3228 NKYG 3231
            N  G
Sbjct: 4389 NSRG 4392



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 9/79 (11%)

Query: 493  FVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPR 552
            F +  S   V EGE VVL   A        TW++         E+    D G  TL++P 
Sbjct: 4232 FNQTISRWTVEEGEHVVLGCEAQSVTKVIYTWRR-------GDEVVQKADHG--TLELPS 4282

Query: 553  AKASDAAWYQCTAQNVAGS 571
             K S+A  Y C A N  GS
Sbjct: 4283 IKRSEAGMYTCEAANHKGS 4301



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 6/102 (5%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
            GK   F C  TG P P V W+   R +    + K+  N+S    + I    +  SG   C
Sbjct: 4330 GKGATFSCLATGNPQPRVEWYY--RPLYSKLSFKLPDNDS--RLVYIEPDDVMRSGFYYC 4385

Query: 466  VARNKSGE-TAFQCRLNVIEKEQVVAPKFVERFSTLNVREGE 506
            VA N  G   + + RL+++     V P+    F+     + E
Sbjct: 4386 VASNSRGRVVSEEGRLDILRSRGAV-PRMAVVFNVTACAQDE 4426



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 5/86 (5%)

Query: 266  PKIAQKPRNSKLQ--EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            P++ ++P + KL    G  A F    +GNP+PRV W+    R + S     +  ++   +
Sbjct: 4314 PELLEEPISFKLALYGGKGATFSCLATGNPQPRVEWY---YRPLYSKLSFKLPDNDSRLV 4370

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVT 349
             +       SG Y  +A N  G +V+
Sbjct: 4371 YIEPDDVMRSGFYYCVASNSRGRVVS 4396



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 11/90 (12%)

Query: 2656 EGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIY 2715
            EG+HV L  + +  T    K+ +     T   G  +    D G  TL + S++  ++G+Y
Sbjct: 4243 EGEHVVLGCEAQSVT----KVIY-----TWRRGDEVVQKADHG--TLELPSIKRSEAGMY 4291

Query: 2716 TCKATNLLGEAVSTASIKIEDRHWLLGESL 2745
            TC+A N  G A     I IE +  LL E +
Sbjct: 4292 TCEAANHKGSAEYHYEIIIEYKPELLEEPI 4321



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 13/43 (30%), Positives = 26/43 (60%)

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            LE+  + + +AG+YTC+A N  G A    ++ ++ +  ++ EP
Sbjct: 4278 LELPSIKRSEAGMYTCEAANHKGSAEYHYEIIIEYKPELLEEP 4320



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 26/121 (21%), Positives = 45/121 (37%), Gaps = 12/121 (9%)

Query: 4634 VAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDY 4693
            V EG+ +   C+          W +GD++++          AD  TL +      + G Y
Sbjct: 4241 VEEGEHVVLGCEAQSVTKVIYTWRRGDEVVQK---------ADHGTLELPSIKRSEAGMY 4291

Query: 4694 KCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ 4753
             C A N  G      ++ +    +    P    L    +Y G+ A F    T   +P ++
Sbjct: 4292 TCEAANHKGSAEYHYEIIIEYKPELLEEPISFKL---ALYGGKGATFSCLATGNPQPRVE 4348

Query: 4754 W 4754
            W
Sbjct: 4349 W 4349


>SB_31858| Best HMM Match : I-set (HMM E-Value=3.7e-08)
          Length = 229

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 14/121 (11%)

Query: 455 VTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQV--VAPKFVERFSTLNVREGEPVVLNA 512
           VTL+D G+  CV  +     A   +   I+   +  V P     F  +  +E   V L  
Sbjct: 112 VTLADGGLYHCVTEHARECAALATKTVNIQVNSIGSVPPNITTSFKNMIFKENATVRLTC 171

Query: 513 RAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
           +A G P P + W  D          RI   GG++TL++ +A A +   Y+C A N A   
Sbjct: 172 QATGNPAPDVYWTMD--------RRRI---GGSNTLEL-KASADNMGVYECVAANGAAPD 219

Query: 573 A 573
           A
Sbjct: 220 A 220



 Score = 43.2 bits (97), Expect = 0.005
 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 18/133 (13%)

Query: 4473 VFVEDSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVR 4532
            V + D  ++  V E+     +C+A        +    G VPP+ T + +N+       VR
Sbjct: 112  VTLADGGLYHCVTEH---ARECAALATKTVNIQVNSIGSVPPNITTSFKNMIFKENATVR 168

Query: 4533 LDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
            L  + TG    DVYW  + +++            G    L L+A   + G YECVA N A
Sbjct: 169  LTCQATGNPAPDVYWTMDRRRI------------GGSNTLELKASADNMGVYECVAANGA 216

Query: 4593 GEARCDAECVVSL 4605
                 DA+  V+L
Sbjct: 217  AP---DAKASVTL 226



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 33/122 (27%), Positives = 46/122 (37%), Gaps = 21/122 (17%)

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D G Y CV  ++        EC     ATK          + PP I    K+ I  E   
Sbjct: 116  DGGLYHCVTEHAR-------ECAAL--ATKTVNIQVNSIGSVPPNITTSFKNMIFKENAT 166

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            +  +C+  G P P V W    + I  S   ++  +AD            + G Y+CVA N
Sbjct: 167  VRLTCQATGNPAPDVYWTMDRRRIGGSNTLELKASAD------------NMGVYECVAAN 214

Query: 4700 SA 4701
             A
Sbjct: 215  GA 216



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 1/56 (1%)

Query: 259 SLGPVSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEI 314
           S+G V PP I    +N   +E A  +   Q +GNP P V W  + +R+  SN  E+
Sbjct: 144 SIGSV-PPNITTSFKNMIFKENATVRLTCQATGNPAPDVYWTMDRRRIGGSNTLEL 198


>SB_19207| Best HMM Match : ig (HMM E-Value=1.2e-11)
          Length = 418

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 6/118 (5%)

Query: 4515 SFTLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            SFT   +N+ + +G  V L  +++  K P ++ WLKNG+ +    + KI        L I
Sbjct: 131  SFTAKVENITMIAGMQVTLKCRLSRKKIPFNITWLKNGQPMTS--KYKIRRFKWGSRLRI 188

Query: 4574 LEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKP-KPQTKAANAPPEIIEPLK 4630
              A  +D+G Y CV   +  E R  A   +S+  T  +P   +   A  P    +P K
Sbjct: 189  KRARQEDAGNYTCVVRANGQEVR--AAGWLSILGTSSRPTMKKVYTAKPPTSTTKPTK 244



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 11/135 (8%)

Query: 271 KPRNSKLQEGADAQFQVQLSGNPRP-RVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQ 329
           K  N  +  G     + +LS    P  +TW KNGQ +  ++K++I      + LR++  +
Sbjct: 135 KVENITMIAGMQVTLKCRLSRKKIPFNITWLKNGQPM--TSKYKIRRFKWGSRLRIKRAR 192

Query: 330 KSDSGHYTLLAENPNGCIVTSGYLAV----ESPTESYVQDQRSQYITDTQQRETEERIEI 385
           + D+G+YT +       +  +G+L++      PT   V   +    T    ++ +E+   
Sbjct: 193 QEDAGNYTCVVRANGQEVRAAGWLSILGTSSRPTMKKVYTAKPPTSTTKPTKKVKEKFPR 252

Query: 386 SEKALAPQFVKVCQD 400
            E    P   KVC +
Sbjct: 253 CE----PYRGKVCAE 263



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 40/165 (24%), Positives = 67/165 (40%), Gaps = 14/165 (8%)

Query: 1440 VTIKPRFVTRPKSIENV--IEGQHVHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIH 1497
            + +  + V+    +EN+  I G  V  +C+L         + W KNGQP+T  ++ R   
Sbjct: 123  IRVTMKAVSFTAKVENITMIAGMQVTLKCRLSR-KKIPFNITWLKNGQPMTSKYKIRRF- 180

Query: 1498 DFGYVALDIIDLIAEDSGIYTC---------RAVNLVGTDEVSCRLTCRSTTDIVRSTQN 1548
             +G   L I     ED+G YTC         RA   +     S R T +        T  
Sbjct: 181  KWG-SRLRIKRARQEDAGNYTCVVRANGQEVRAAGWLSILGTSSRPTMKKVYTAKPPTST 239

Query: 1549 EAGLEQIQVLEDRSKYHRTDMVDEVTTQAPICTTSLKNVEIKEGQ 1593
                ++++    R + +R  +  E    +P+  TS  +  I EG+
Sbjct: 240  TKPTKKVKEKFPRCEPYRGKVCAEFMYGSPVYATSRHHQRIIEGK 284



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 4/78 (5%)

Query: 2640 QAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL 2699
            +A  FT  +++   ++ G  V L+ ++  +  P   I W KNG  +T+  +++  F +G 
Sbjct: 128  KAVSFTAKVENIT-MIAGMQVTLKCRLSRKKIP-FNITWLKNGQPMTSKYKIRR-FKWGS 184

Query: 2700 VTLSINSLRNDDSGIYTC 2717
              L I   R +D+G YTC
Sbjct: 185  -RLRIKRARQEDAGNYTC 201



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 11/114 (9%)

Query: 4637 GQAIEFSCKIVGKPLP-TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            G  +   C++  K +P  + W K  + +  SKY ++ R      LRI  A  ED G+Y C
Sbjct: 144  GMQVTLKCRLSRKKIPFNITWLKNGQPMT-SKY-KIRRFKWGSRLRIKRARQEDAGNYTC 201

Query: 4696 VAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIK 4749
            V   +   V  A  L +        +          VY  +P    T+ T K+K
Sbjct: 202  VVRANGQEVRAAGWLSILGTSSRPTMKK--------VYTAKPPTSTTKPTKKVK 247



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 5/93 (5%)

Query: 2776 FISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVS-LD 2834
            F + + NI    G  +  +C +   + P   I W  N +P+ S  +YK    F + S L 
Sbjct: 132  FTAKVENITMIAGMQVTLKCRLSRKKIP-FNITWLKNGQPMTS--KYKIRR-FKWGSRLR 187

Query: 2835 ITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            I    +ED+G YTC    +      +G L   G
Sbjct: 188  IKRARQEDAGNYTCVVRANGQEVRAAGWLSILG 220



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 3/55 (5%)

Query: 943 VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSA 997
           + WLK+G+P+ +  +I   F +G   L IK     DAG+YTC    A GQ   +A
Sbjct: 162 ITWLKNGQPMTSKYKIRR-FKWG-SRLRIKRARQEDAGNYTC-VVRANGQEVRAA 213



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 3/55 (5%)

Query: 804 VEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTA 858
           + W K+G+P+T+  +I   F +G   L I   R EDAG+YT   V   G+ +  A
Sbjct: 162 ITWLKNGQPMTSKYKIRR-FKWGS-RLRIKRARQEDAGNYTC-VVRANGQEVRAA 213



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 1706 VITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDF 1765
            V  +A  FT  +++I +        + RL     P   + WL+NG P+ +  ++     +
Sbjct: 125  VTMKAVSFTAKVENITMIAGMQVTLKCRLSRKKIP-FNITWLKNGQPMTSKYKIRRFK-W 182

Query: 1766 GYVALNMKYVNPEDSGTYTC 1785
            G   L +K    ED+G YTC
Sbjct: 183  GS-RLRIKRARQEDAGNYTC 201



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 3/89 (3%)

Query: 1055 IVEGQSAHFEARVEPQSDLTMTVEWYFNGKQITSANRIQTYHDFGYVALDIASVRAEDSG 1114
            ++ G     + R+  +  +   + W  NG+ +TS  +I+ +  +G   L I   R ED+G
Sbjct: 141  MIAGMQVTLKCRLS-RKKIPFNITWLKNGQPMTSKYKIRRFK-WGS-RLRIKRARQEDAG 197

Query: 1115 VYTVVARNAAGEAQLSASMTVETRSSIDT 1143
             YT V R    E + +  +++   SS  T
Sbjct: 198  NYTCVVRANGQEVRAAGWLSILGTSSRPT 226


>SB_18521| Best HMM Match : ig (HMM E-Value=7.5e-11)
          Length = 1033

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 40/158 (25%), Positives = 64/158 (40%), Gaps = 16/158 (10%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  TGRP P VTWF++D+++        + N      +   N  +    V+ C ARN  G
Sbjct: 293 CFPTGRPTPNVTWFVDDKELVTSTKQYNISNYGRVLKVAFGNAVM----VIKCTARNTVG 348

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG-TPTPRITWQKDGVPI 531
             +   R        V +P    R + + V+ GE + L         +P + W  +G  I
Sbjct: 349 SKSAITR--------VYSPTGSVRPTKIFVKSGESLTLTVGIADLLASPHVAWLFNGKTI 400

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            P   + +  +    +L I   + SD+  YQ     VA
Sbjct: 401 SPASRISLSIN---KSLVIKFLQVSDSGIYQSLLNGVA 435



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 14/131 (10%)

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDK-LIKPSKYFQMSRTADEYTLRISEAFPEDEG 4691
            I+   + +E  C   G+P P V W+  DK L+  +K + +S     Y   +  AF     
Sbjct: 282  ILKPEENVELHCFPTGRPTPNVTWFVDDKELVTSTKQYNIS----NYGRVLKVAFGNAVM 337

Query: 4692 DYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI-KP 4750
              KC A N+ G  + +A  +V  P       ++ P + I V  G+       I   +  P
Sbjct: 338  VIKCTARNTVG--SKSAITRVYSP-----TGSVRPTK-IFVKSGESLTLTVGIADLLASP 389

Query: 4751 TIQWLREGALI 4761
             + WL  G  I
Sbjct: 390  HVAWLFNGKTI 400



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
           L ++  E V L+    G PTP +TW  D   ++ + + + +       L +  A  +   
Sbjct: 281 LILKPEENVELHCFPTGRPTPNVTWFVDDKELVTSTK-QYNISNYGRVLKV--AFGNAVM 337

Query: 560 WYQCTAQNVAGSTATRARLY 579
             +CTA+N  GS +   R+Y
Sbjct: 338 VIKCTARNTVGSKSAITRVY 357


>SB_44830| Best HMM Match : I-set (HMM E-Value=1.1e-08)
          Length = 480

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 1/73 (1%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            I+  CK  G P  T  W K  K I   +  Q     +++ LR+ +  P D GDY CV  N
Sbjct: 231  IKLKCKAEGTPPLTFTWLKNGKPITHRR-LQPGLKTNQWYLRLRDLVPADTGDYTCVVSN 289

Query: 4700 SAGRVTVAAKLKV 4712
              G++     L+V
Sbjct: 290  PYGQINHTYTLQV 302



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 3/76 (3%)

Query: 1328 VHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQA 1387
            + L+C+ +  G   +   W  NGKPI T  R +P  + +   L L  + P D+G YTC  
Sbjct: 231  IKLKCKAE--GTPPLTFTWLKNGKPI-THRRLQPGLKTNQWYLRLRDLVPADTGDYTCVV 287

Query: 1388 TNQLGEAVTSCALRVI 1403
            +N  G+   +  L+V+
Sbjct: 288  SNPYGQINHTYTLQVV 303



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 4531 VRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAIN 4590
            ++L  K  GT P+   WLKNGK +        L+ +  Y L + +  P D+G Y CV  N
Sbjct: 231  IKLKCKAEGTPPLTFTWLKNGKPITHRRLQPGLKTNQWY-LRLRDLVPADTGDYTCVVSN 289

Query: 4591 SAGE 4594
              G+
Sbjct: 290  PYGQ 293



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 6/87 (6%)

Query: 3972 PPRFVTQIQSQTSLVEM---ETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDF 4028
            PP F  Q + + + +      T K +C+    G P +   W  NGKP+ H+ R  P    
Sbjct: 209  PPYFAQQQKMKGTFIAWPAWHTIKLKCKAE--GTPPLTFTWLKNGKPITHR-RLQPGLKT 265

Query: 4029 GYVAMNFGWVYPEDSGEYLCRATNLYG 4055
                +    + P D+G+Y C  +N YG
Sbjct: 266  NQWYLRLRDLVPADTGDYTCVVSNPYG 292



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 10/120 (8%)

Query: 237 RESITKRYVGESDVQISTEIDRSLGPVS-----PPKIAQKPRNSKLQEGADAQFQVQLS- 290
           RE++ +  +  +DV +   + R +  ++     PP  AQ+ +         A   ++L  
Sbjct: 176 RETLNENAMHATDVSLVLLLLRGIAALATSSRGPPYFAQQQKMKGTFIAWPAWHTIKLKC 235

Query: 291 ---GNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
              G P    TW KNG+ + +      + T N   LR+R+   +D+G YT +  NP G I
Sbjct: 236 KAEGTPPLTFTWLKNGKPITHRRLQPGLKT-NQWYLRLRDLVPADTGDYTCVVSNPYGQI 294



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P L   WL+NG PI    RL          L ++ + P D+G YTC   N  G+   +
Sbjct: 239  GTPPLTFTWLKNGKPI-THRRLQPGLKTNQWYLRLRDLVPADTGDYTCVVSNPYGQINHT 297

Query: 1798 STLFV 1802
             TL V
Sbjct: 298  YTLQV 302



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%)

Query: 937  GDSTLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTS 996
            G   L   WLK+G+P+    R+          L ++ +   D G YTC   N  GQ   +
Sbjct: 239  GTPPLTFTWLKNGKPI-THRRLQPGLKTNQWYLRLRDLVPADTGDYTCVVSNPYGQINHT 297

Query: 997  ANLTIVT 1003
              L +VT
Sbjct: 298  YTLQVVT 304



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 1462 VHFECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRA 1521
            +  +CK E      L   W KNG+P+T   R +P        L + DL+  D+G YTC  
Sbjct: 231  IKLKCKAEGTPP--LTFTWLKNGKPIT-HRRLQPGLKTNQWYLRLRDLVPADTGDYTCVV 287

Query: 1522 VNLVG 1526
             N  G
Sbjct: 288  SNPYG 292



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 3/65 (4%)

Query: 90  KFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTAR 149
           K + K  G P    +W +   P+       ++   +T    L ++ + P D G+YTC   
Sbjct: 232 KLKCKAEGTPPLTFTWLKNGKPITHRR---LQPGLKTNQWYLRLRDLVPADTGDYTCVVS 288

Query: 150 NQYGE 154
           N YG+
Sbjct: 289 NPYGQ 293



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/92 (27%), Positives = 36/92 (39%), Gaps = 6/92 (6%)

Query: 3694 PPRFTVEIKDN---IDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750
            PP F  + K     I  P    +   C+ E  G P +   W  NG+P  T  R+      
Sbjct: 209  PPYFAQQQKMKGTFIAWPAWHTIKLKCKAE--GTPPLTFTWLKNGKPI-THRRLQPGLKT 265

Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
                L +  +   D G+YTC  +N +G    T
Sbjct: 266  NQWYLRLRDLVPADTGDYTCVVSNPYGQINHT 297



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 1195 IHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVALDIIHATSADTGEYTVRA 1254
            I L+C+ E  G P +   W  NG+ +T   R +         L +     ADTG+YT   
Sbjct: 231  IKLKCKAE--GTPPLTFTWLKNGKPIT-HRRLQPGLKTNQWYLRLRDLVPADTGDYTCVV 287

Query: 1255 VNHLGSAHTSAIVRVIERSDIVTD 1278
             N  G  + +  ++V+  S  + D
Sbjct: 288  SNPYGQINHTYTLQVVTVSGTLPD 311


>SB_37776| Best HMM Match : fn3 (HMM E-Value=1.4e-22)
          Length = 1296

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 51/215 (23%), Positives = 73/215 (33%), Gaps = 26/215 (12%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVY-WLKNGKKVQPDIRNKILEEDGTYTL 4571
            PPS  + +  V V      RL     G    +V  W + G ++ P  +  +LE     +L
Sbjct: 37   PPSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPPDKFVVLERG---SL 93

Query: 4572 LILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIE-PLK 4630
            LI +    D G Y C   N  G                 KP          P   E P  
Sbjct: 94   LIRKVKRSDMGTYVCTPSNYIGAG---------------KPGTTNLVVQVVPTFTEVPSS 138

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDE 4690
               V  G+ I F C  V + +P+V W       +  K F       +  L I      D 
Sbjct: 139  VVSVRVGEEIRFKCSAVSETVPSVSWR------RVGKAFSNRTQTSKGLLTILGVQTVDH 192

Query: 4691 GDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            G+Y+CVA    G+      L V        + A++
Sbjct: 193  GEYECVAETDKGKAVHTTTLNVISVPSRPTITAVS 227



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 49/181 (27%), Positives = 68/181 (37%), Gaps = 16/181 (8%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVT-WFINDRQIRDDYNHKILVNESGNHAL 450
           P  + +     V E    R  C   G P  EVT W     ++      K +V E G+  L
Sbjct: 38  PSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPP--DKFVVLERGS--L 93

Query: 451 MITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVE-RFSTLNVREGEPVV 509
           +I  V  SD G   C   N  G         V++    V P F E   S ++VR GE + 
Sbjct: 94  LIRKVKRSDMGTYVCTPSNYIGAGKPGTTNLVVQ----VVPTFTEVPSSVVSVRVGEEIR 149

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
               AV    P ++W++ G         R  T  G   L I   +  D   Y+C A+   
Sbjct: 150 FKCSAVSETVPSVSWRRVGKAF----SNRTQTSKG--LLTILGVQTVDHGEYECVAETDK 203

Query: 570 G 570
           G
Sbjct: 204 G 204



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 52/202 (25%), Positives = 79/202 (39%), Gaps = 23/202 (11%)

Query: 4410 PPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLI-KWYRENFPIKNSPDFQIHTFSTKSIL 4468
            PP          V E+  AR     +G P   + KW R    +     F +     +  L
Sbjct: 37   PPSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPPDKFVV---LERGSL 93

Query: 4469 IIRQVFVEDSAVFAAVAENRGGTAKC-SANLVVEEKRRQGRGGIVPPSFT-LTAQNVNVT 4526
            +IR+V   D   +     N  G  K  + NLVV+          V P+FT + +  V+V 
Sbjct: 94   LIRKVKRSDMGTYVCTPSNYIGAGKPGTTNLVVQ----------VVPTFTEVPSSVVSVR 143

Query: 4527 SGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYEC 4586
             G+ +R            V W + GK       N+     G  T+L ++    D G+YEC
Sbjct: 144  VGEEIRFKCSAVSETVPSVSWRRVGKAFS----NRTQTSKGLLTILGVQTV--DHGEYEC 197

Query: 4587 VAINSAGEA-RCDAECVVSLPA 4607
            VA    G+A       V+S+P+
Sbjct: 198  VAETDKGKAVHTTTLNVISVPS 219



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 50/195 (25%), Positives = 70/195 (35%), Gaps = 19/195 (9%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTV-QWYK-GDKLIKPSKYFQMSRTADEYT 4679
            PP II       V E       C   G P   V +W + G +L  P K+  + R +    
Sbjct: 37   PPSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPPDKFVVLERGS---- 92

Query: 4680 LRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT--PLRDIVVYEGQP 4737
            L I +    D G Y C   N  G         V Q      +P  T  P   + V  G+ 
Sbjct: 93   LLIRKVKRSDMGTYVCTPSNYIGAGKPGTTNLVVQV-----VPTFTEVPSSVVSVRVGEE 147

Query: 4738 AQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATT 4797
             +FK    S+  P++ W R G        F    + +  +L I      D G + C A T
Sbjct: 148  IRFKCSAVSETVPSVSWRRVGKA------FSNRTQTSKGLLTILGVQTVDHGEYECVAET 201

Query: 4798 AAGQVETSAKLVVKS 4812
              G+   +  L V S
Sbjct: 202  DKGKAVHTTTLNVIS 216



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 36/133 (27%), Positives = 52/133 (39%), Gaps = 12/133 (9%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I   K +D GTY C  +N  G  +       V       P FT    ++  ++ G+  
Sbjct: 93   LLIRKVKRSDMGTYVCTPSNYIGAGKPGTTNLVVQVV----PTFTEVPSSVVSVRVGEEI 148

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAY 3227
             F+C+ V    P   + W   G+    S R +T       +L I   Q  D GEY C A 
Sbjct: 149  RFKCSAVSETVPS--VSWRRVGKAF--SNRTQTSKG----LLTILGVQTVDHGEYECVAE 200

Query: 3228 NKYGEDFTRATIN 3240
               G+     T+N
Sbjct: 201  TDKGKAVHTTTLN 213



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 11/103 (10%)

Query: 3825 IVSTPPKFITQIKSH--TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVY 3882
            +V   P F T++ S   +V   E +RF+C    +  P   + W R GK   +    RT  
Sbjct: 125  VVQVVPTF-TEVPSSVVSVRVGEEIRFKCSAVSETVPS--VSWRRVGKAFSN----RTQT 177

Query: 3883 DMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLP 3925
              G   L IL V   D GEY C A  D G+     T++   +P
Sbjct: 178  SKGL--LTILGVQTVDHGEYECVAETDKGKAVHTTTLNVISVP 218



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 31/104 (29%), Positives = 42/104 (40%), Gaps = 8/104 (7%)

Query: 1838 VAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSN 1897
            + V   P F    +    +  G+   ++C       P+  V W   GK   +    RT  
Sbjct: 124  LVVQVVPTFTEVPSSVVSVRVGEEIRFKCSAVSETVPS--VSWRRVGKAFSN----RTQT 177

Query: 1898 DFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
              G   L IL V   D GEY C A  + G+AV +  LNV S  S
Sbjct: 178  SKGL--LTILGVQTVDHGEYECVAETDKGKAVHTTTLNVISVPS 219



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 8/94 (8%)

Query: 3048 PEFTTVFKDIVDISEGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVV 3107
            P FT V   +V +  G+   ++ S +     S  + W   GK    S+R +T       +
Sbjct: 130  PTFTEVPSSVVSVRVGEEIRFKCSAVSETVPS--VSWRRVGKAF--SNRTQTSKG----L 181

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECV 3141
            L ILG +T D G Y C A    G+A  +  L  +
Sbjct: 182  LTILGVQTVDHGEYECVAETDKGKAVHTTTLNVI 215



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 8/93 (8%)

Query: 2109 PVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVA 2168
            P F    +S+ +++ G+   F+C    +++   ++ W   G+     +R +T+       
Sbjct: 130  PTFTEVPSSVVSVRVGEEIRFKCSA--VSETVPSVSWRRVGKAF--SNRTQTSKGL---- 181

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L IL     D G Y C A    G+AV+T TL V
Sbjct: 182  LTILGVQTVDHGEYECVAETDKGKAVHTTTLNV 214



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 8/93 (8%)

Query: 3420 PVFTVPLSNIENLREGENAHFEARLTPTDDPNLKVEWYWNGKSLKAGSRFRTFCDFGFVI 3479
            P FT   S++ ++R GE   F+        P+  V W   GK+       RT    G  +
Sbjct: 130  PTFTEVPSSVVSVRVGEEIRFKCSAVSETVPS--VSWRRVGKAFSN----RTQTSKG--L 181

Query: 3480 LEISPTYPEDSGEYLCRAYNNYGEAVTTASMKV 3512
            L I      D GEY C A  + G+AV T ++ V
Sbjct: 182  LTILGVQTVDHGEYECVAETDKGKAVHTTTLNV 214



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 8/95 (8%)

Query: 390 LAPQFVKVCQDR-DVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           + P F +V      V  G+  RF C       P V+W    R++   ++++    ++   
Sbjct: 128 VVPTFTEVPSSVVSVRVGEEIRFKCSAVSETVPSVSW----RRVGKAFSNR---TQTSKG 180

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVI 483
            L I  V   D G   CVA    G+      LNVI
Sbjct: 181 LLTILGVQTVDHGEYECVAETDKGKAVHTTTLNVI 215



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 6/84 (7%)

Query: 71  PPIFEQIFKNARFAQGGNAKFEGKLRGNP-TPVVSWTRKKAPLVECNKYSMRYNEQTGDV 129
           PP    I       +  +A+      GNP T V  WTR    L   +K+ +    + G  
Sbjct: 37  PPSIIVISSVVTVGENTDARLPCVSEGNPATEVTKWTRVGGELGPPDKFVVL---ERG-- 91

Query: 130 SLLIKQIGPGDEGEYTCTARNQYG 153
           SLLI+++   D G Y CT  N  G
Sbjct: 92  SLLIRKVKRSDMGTYVCTPSNYIG 115


>SB_25692| Best HMM Match : I-set (HMM E-Value=2e-20)
          Length = 104

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C VTG P P +TW  N +++  + +  ++ N   N +L++  V+ SD G  TC ARN  G
Sbjct: 36  CPVTGVPAPTITWSRNGQEMPANGDGYLVTN---NGSLILEKVSSSDIGRYTCTARNAFG 92

Query: 473 ETAFQCRLNVI 483
           +      +NV+
Sbjct: 93  KDNANSTVNVM 103



 Score = 42.3 bits (95), Expect = 0.009
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           V L+    G P P ITW ++G  +  N +  + T+ G+  L+  +  +SD   Y CTA+N
Sbjct: 32  VTLHCPVTGVPAPTITWSRNGQEMPANGDGYLVTNNGSLILE--KVSSSDIGRYTCTARN 89

Query: 568 VAG 570
             G
Sbjct: 90  AFG 92



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 3157 NIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQN 3216
            NI  L D       C V  V  P   I W  NGQ M  +     V++ G ++L+     +
Sbjct: 23   NITALTD-TLVTLHCPVTGVPAPT--ITWSRNGQEMPANGDGYLVTNNGSLILE--KVSS 77

Query: 3217 HDSGEYVCRAYNKYGEDFTRATIN 3240
             D G Y C A N +G+D   +T+N
Sbjct: 78   SDIGRYTCTARNAFGKDNANSTVN 101



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 2/57 (3%)

Query: 289 LSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           ++G P P +TW +NGQ +  +    ++T  N+ +L +     SD G YT  A N  G
Sbjct: 38  VTGVPAPTITWSRNGQEMPANGDGYLVT--NNGSLILEKVSSSDIGRYTCTARNAFG 92



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 6/59 (10%)

Query: 97  GNPTPVVSWTRKKAPL-VECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYGE 154
           G P P ++W+R    +    + Y +     T + SL+++++   D G YTCTARN +G+
Sbjct: 40  GVPAPTITWSRNGQEMPANGDGYLV-----TNNGSLILEKVSSSDIGRYTCTARNAFGK 93



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 2/62 (3%)

Query: 3859 PKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKAT 3918
            P   I W RNG+ +P+      V + G  SL +  V + D G Y C A N FG+D   +T
Sbjct: 42   PAPTITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGKDNANST 99

Query: 3919 IS 3920
            ++
Sbjct: 100  VN 101



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 4522 NVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDS 4581
            N+   +  LV L   VTG     + W +NG+++  +    ++  +G  +L++ +    D 
Sbjct: 23   NITALTDTLVTLHCPVTGVPAPTITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDI 80

Query: 4582 GKYECVAINSAGE 4594
            G+Y C A N+ G+
Sbjct: 81   GRYTCTARNAFGK 93



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 2/58 (3%)

Query: 4744 ITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQ 4801
            +T    PTI W R G  +P   D  ++   NN  L++      D G +TC A  A G+
Sbjct: 38   VTGVPAPTITWSRNGQEMPANGDGYLVT--NNGSLILEKVSSSDIGRYTCTARNAFGK 93



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 3701 IKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYI 3760
            I DNI       V   C V  V  PT  I W  NG+        + + + G  +L ++ +
Sbjct: 20   IGDNITALTDTLVTLHCPVTGVPAPT--ITWSRNGQEMPANGDGYLVTNNG--SLILEKV 75

Query: 3761 YARDAGEYTCRATNKWGSATTTAKI 3785
             + D G YTC A N +G     + +
Sbjct: 76   SSSDIGRYTCTARNAFGKDNANSTV 100



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 664 GDPTMKIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETK 723
           G P   I W +NGQ + A+     +   G + L+ +S +  D G YTC A +A G     
Sbjct: 40  GVPAPTITWSRNGQEMPANGDGYLVTNNGSLILEKVSSS--DIGRYTCTARNAFGKDNAN 97

Query: 724 AVLHV 728
           + ++V
Sbjct: 98  STVNV 102



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 16/60 (26%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W ++G+ + A+       N G  +L ++ V+  D G YTC A NA G+   ++ + ++
Sbjct: 46   ITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGKDNANSTVNVM 103



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 1738 GDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTS 1797
            G P   + W RNG  + A+     + + G  +L ++ V+  D G YTC A N  G+   +
Sbjct: 40   GVPAPTITWSRNGQEMPANGDGYLVTNNG--SLILEKVSSSDIGRYTCTARNAFGKDNAN 97

Query: 1798 STLFV 1802
            ST+ V
Sbjct: 98   STVNV 102


>SB_19559| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 771

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 9/120 (7%)

Query: 230 LLREVSFRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEGADAQFQVQL 289
           LL+++  +    K+ V   ++   +E    L P  PP I ++P +  +QEG   +   + 
Sbjct: 100 LLQDMRTKCRTVKQLVSYLELMEHSEALELLKPDEPPVITEQPMSLPVQEGLKLELTCRA 159

Query: 290 SGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVT 349
           +G P P+  W KNG  L              +TL +    + D G Y  +  N  G + T
Sbjct: 160 TGFPPPQYQWVKNGAEL---------PYGCDSTLTIDRVSRQDQGKYFCIISNRIGSVKT 210



 Score = 44.0 bits (99), Expect = 0.003
 Identities = 22/63 (34%), Positives = 30/63 (47%)

Query: 4100 QVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKL 4159
            + +E  K   PPV    P ++ V+EG      CR TG P P+  W+ NG  +  G    L
Sbjct: 125  EALELLKPDEPPVITEQPMSLPVQEGLKLELTCRATGFPPPQYQWVKNGAELPYGCDSTL 184

Query: 4160 TYD 4162
            T D
Sbjct: 185  TID 187



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 34/138 (24%), Positives = 56/138 (40%), Gaps = 17/138 (12%)

Query: 357 SPTESYVQDQRS------QYITDTQQRETEERIEISEKALAPQFVKVCQDRDVTEGKMTR 410
           SPTE  +QD R+      Q ++  +  E  E +E+ +    P   +      V EG    
Sbjct: 95  SPTECLLQDMRTKCRTVKQLVSYLELMEHSEALELLKPDEPPVITEQPMSLPVQEGLKLE 154

Query: 411 FDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNK 470
             CR TG P P+  W  N  ++   Y          +  L I  V+  D G   C+  N+
Sbjct: 155 LTCRATGFPPPQYQWVKNGAEL--PY--------GCDSTLTIDRVSRQDQGKYFCIISNR 204

Query: 471 SGET-AFQCRLNVIEKEQ 487
            G    ++  +NV+  ++
Sbjct: 205 IGSVKTYEVEVNVLRVQR 222



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 13/148 (8%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP  T    ++ V  G  + L  + TG  P    W+KNG +         L      TL 
Sbjct: 135  PPVITEQPMSLPVQEGLKLELTCRATGFPPPQYQWVKNGAE---------LPYGCDSTLT 185

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQT--KAANAPPEIIEPLK 4630
            I     QD GKY C+  N  G  +     V  L   + + + +T    +++ P I +  +
Sbjct: 186  IDRVSRQDQGKYFCIISNRIGSVKTYEVEVNVLRVQRHEQEEETPLPESSSLPYITQQPQ 245

Query: 4631 DKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
              ++  G     +C   G P+   QW+K
Sbjct: 246  SALIPIGHRYHLTCGTKG-PV-KFQWFK 271



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 30/84 (35%), Positives = 36/84 (42%), Gaps = 9/84 (10%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P   E+  +L V+EG  + L  RA G P P+  W K+G       EL    D   STL I
Sbjct: 136 PVITEQPMSLPVQEGLKLELTCRATGFPPPQYQWVKNGA------ELPYGCD---STLTI 186

Query: 551 PRAKASDAAWYQCTAQNVAGSTAT 574
            R    D   Y C   N  GS  T
Sbjct: 187 DRVSRQDQGKYFCIISNRIGSVKT 210



 Score = 40.3 bits (90), Expect = 0.037
 Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 9/120 (7%)

Query: 4585 ECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSC 4644
            EC+  +   + R   + V  L   +     +    + PP I E      V EG  +E +C
Sbjct: 98   ECLLQDMRTKCRTVKQLVSYLELMEHSEALELLKPDEPPVITEQPMSLPVQEGLKLELTC 157

Query: 4645 KIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRV 4704
            +  G P P  QW K           ++    D  TL I     +D+G Y C+  N  G V
Sbjct: 158  RATGFPPPQYQWVKNGA--------ELPYGCDS-TLTIDRVSRQDQGKYFCIISNRIGSV 208



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 37/156 (23%), Positives = 61/156 (39%), Gaps = 21/156 (13%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEPLPLIKWYRENFPIKNSPDFQIHTFST 4464
            +KP +PP+ T++     V E  +        G P P  +W      +KN  +     +  
Sbjct: 130  LKPDEPPVITEQPMSLPVQEGLKLELTCRATGFPPPQYQW------VKNGAEL---PYGC 180

Query: 4465 KSILIIRQVFVEDSAVFAAVAENRGGTAK---CSANLVVEEKRRQGRGGIVP-----PSF 4516
             S L I +V  +D   +  +  NR G+ K      N++  ++  Q     +P     P  
Sbjct: 181  DSTLTIDRVSRQDQGKYFCIISNRIGSVKTYEVEVNVLRVQRHEQEEETPLPESSSLPYI 240

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLKNG 4551
            T   Q+  +  G    L     GTK P+   W K+G
Sbjct: 241  TQQPQSALIPIGHRYHL---TCGTKGPVKFQWFKDG 273



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 11/91 (12%)

Query: 3691 KPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDF 3750
            KP+ P    E   ++ V EG  +   CR    G P  +  W  NG     G         
Sbjct: 131  KPDEPPVITEQPMSLPVQEGLKLELTCRA--TGFPPPQYQWVKNGAELPYGCDS------ 182

Query: 3751 GFIALDIDYIYARDAGEYTCRATNKWGSATT 3781
                L ID +  +D G+Y C  +N+ GS  T
Sbjct: 183  ---TLTIDRVSRQDQGKYFCIISNRIGSVKT 210



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 35/155 (22%), Positives = 60/155 (38%), Gaps = 16/155 (10%)

Query: 1114 GVYTVVARNAAGEAQLSA-SMTVETRSSIDTSSIHRGLYEKTRHIEES-KFVEPMYQIEE 1171
            G+ +V+   +  + Q+S   +         T  + + +  K R +++   ++E M   E 
Sbjct: 67   GLISVMPEGSYSQLQVSQFGLAAMRMGGSPTECLLQDMRTKCRTVKQLVSYLELMEHSEA 126

Query: 1172 ISKSKPVFVQPLSNPP---PVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKT 1228
            +   KP     ++  P   PV EG  + L CR    G P  + +W  NG  +  G     
Sbjct: 127  LELLKPDEPPVITEQPMSLPVQEGLKLELTCR--ATGFPPPQYQWVKNGAELPYGCD--- 181

Query: 1229 YYDFGFVALDIIHATSADTGEYTVRAVNHLGSAHT 1263
                    L I   +  D G+Y     N +GS  T
Sbjct: 182  ------STLTIDRVSRQDQGKYFCIISNRIGSVKT 210



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 50/225 (22%), Positives = 88/225 (39%), Gaps = 25/225 (11%)

Query: 1735 IPVGDPKLRVEWLRNG----VPIEASNRLTTMHDFGYV-ALNMK-YVNPEDSGTYTCRAI 1788
            +PV  PK   +   N     +P    ++L+ M D  Y   LN +  ++    G+Y+   +
Sbjct: 23   VPVMAPKYDKQKYYNAQIRELPYSIIHKLSAMLDDPYNRTLNWQGLISVMPEGSYSQLQV 82

Query: 1789 NELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDVEVAVNQAPRFIT 1848
            ++ G A               + ++  +  Q +  LE     +  E +E+     P  IT
Sbjct: 83   SQFGLAAMRMGGSPTECLLQDMRTKCRTVKQLVSYLE---LMEHSEALELLKPDEPPVIT 139

Query: 1849 QLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILT 1908
            +      + EG      CR   +P P  + +W  NG  L  G           + L I  
Sbjct: 140  EQPMSLPVQEGLKLELTCRATGFPPP--QYQWVKNGAELPYGCD---------STLTIDR 188

Query: 1909 VYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESALE 1953
            V  +D G+Y C   N +G +V +  + V    +++R  +HE   E
Sbjct: 189  VSRQDQGKYFCIISNRIG-SVKTYEVEV----NVLRVQRHEQEEE 228


>SB_16914| Best HMM Match : I-set (HMM E-Value=2.3e-10)
          Length = 94

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 29/86 (33%), Positives = 37/86 (43%), Gaps = 11/86 (12%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P  +       VR GE + L     G PTP ++W K G           H+ GG +    
Sbjct: 2   PPEITPIQNTTVRAGETITLTCAVAGYPTPSVSWSKAGSG---------HSTGG-NVFTK 51

Query: 551 PRAKASDAAWYQCTAQN-VAGSTATR 575
           P A   D   Y CTA N V+G+T TR
Sbjct: 52  PGATKEDTGQYVCTAVNTVSGNTQTR 77



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 11/79 (13%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PPEI  P+++  V  G+ I  +C + G P P+V W K             S   + +T  
Sbjct: 2    PPEIT-PIQNTTVRAGETITLTCAVAGYPTPSVSWSKAGS--------GHSTGGNVFTK- 51

Query: 4682 ISEAFPEDEGDYKCVAYNS 4700
               A  ED G Y C A N+
Sbjct: 52   -PGATKEDTGQYVCTAVNT 69


>SB_13005| Best HMM Match : PSI (HMM E-Value=2.9e-11)
          Length = 829

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 30/98 (30%), Positives = 41/98 (41%), Gaps = 5/98 (5%)

Query: 66  PGEPSPPIFEQIFKNARFAQGGNAKFEGKLRGNPTP-VVSWTRKKAPLVECNKYSMRYNE 124
           P EP     E I +N     G     E K  G P P VV+W +    L    KY ++   
Sbjct: 399 PSEPPSCAIEVIKENP----GQETILECKAEGIPVPEVVAWEKDSVKLAYDGKYRIQKTG 454

Query: 125 QTGDVSLLIKQIGPGDEGEYTCTARNQYGEAICSVYIQ 162
             G   L I   G    G YTC  ++  G+A CS+ ++
Sbjct: 455 SQGSQRLSISPFGVKHLGTYTCQVQSTMGKADCSLEVK 492



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 7/91 (7%)

Query: 2117 SLENLKE--GDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRT--THDFGYVALDIL 2172
            ++E +KE  G     EC+ E I  P + + W  +  K+    +YR   T   G   L I 
Sbjct: 406  AIEVIKENPGQETILECKAEGIPVPEV-VAWEKDSVKLAYDGKYRIQKTGSQGSQRLSIS 464

Query: 2173 YTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
                +  GTY C+  + +G+A   C+L+V G
Sbjct: 465  PFGVKHLGTYTCQVQSTMGKA--DCSLEVKG 493



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 36/144 (25%), Positives = 56/144 (38%), Gaps = 15/144 (10%)

Query: 406 GKMTRFDCRVTGRPYPE-VTWFINDRQIRDDYNHKI-LVNESGNHALMITNVTLSDSGVV 463
           G+ T  +C+  G P PE V W  +  ++  D  ++I      G+  L I+   +   G  
Sbjct: 415 GQETILECKAEGIPVPEVVAWEKDSVKLAYDGKYRIQKTGSQGSQRLSISPFGVKHLGTY 474

Query: 464 TCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRIT 523
           TC  ++  G+    C L V      V   F         +       +  A GTP P I+
Sbjct: 475 TCQVQSTMGKA--DCSLEVKGSLPAVTSGF--------TKHALKTYFSCTAKGTPLPSIS 524

Query: 524 WQK--DGV-PIIPNPELRIHTDGG 544
             K   GV  ++P   + I  D G
Sbjct: 525 MYKVSGGVSQLLPGNNVSIEQDMG 548



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 2657 GQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA--RLKSTFDFGLVTLSINSLRNDDSGI 2714
            GQ   LE + E    P + + W K+ V L      R++ T   G   LSI+       G 
Sbjct: 415  GQETILECKAEGIPVPEV-VAWEKDSVKLAYDGKYRIQKTGSQGSQRLSISPFGVKHLGT 473

Query: 2715 YTCKATNLLGEAVSTASIK 2733
            YTC+  + +G+A  +  +K
Sbjct: 474  YTCQVQSTMGKADCSLEVK 492



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 5/98 (5%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTK-PIDVYWLKNGKKVQPDIRNKILE--EDGTY 4569
            PPS  +     N   GQ   L+ K  G   P  V W K+  K+  D + +I +    G+ 
Sbjct: 402  PPSCAIEVIKEN--PGQETILECKAEGIPVPEVVAWEKDSVKLAYDGKYRIQKTGSQGSQ 459

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPA 4607
             L I     +  G Y C   ++ G+A C  E   SLPA
Sbjct: 460  RLSISPFGVKHLGTYTCQVQSTMGKADCSLEVKGSLPA 497



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 7/98 (7%)

Query: 4622 PPEI-IEPLKDKIVAEGQAIEFSCKIVGKPLP-TVQWYKGD-KLIKPSKY-FQMSRTADE 4677
            PP   IE +K+     GQ     CK  G P+P  V W K   KL    KY  Q + +   
Sbjct: 402  PPSCAIEVIKEN---PGQETILECKAEGIPVPEVVAWEKDSVKLAYDGKYRIQKTGSQGS 458

Query: 4678 YTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQP 4715
              L IS    +  G Y C   ++ G+   + ++K + P
Sbjct: 459  QRLSISPFGVKHLGTYTCQVQSTMGKADCSLEVKGSLP 496


>SB_43138| Best HMM Match : Pox_A_type_inc (HMM E-Value=1.3e-14)
          Length = 1709

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 36/155 (23%), Positives = 70/155 (45%), Gaps = 6/155 (3%)

Query: 4250 RPELKPKVIKEPETEWQQS-VKRKK-NEEYYNKLQELENEQVIKESRLRESTHQYAIPGD 4307
            + EL+ ++ K+ E   +++  KR+K  EEY  KL+ +  E V + S+ +E  +Q      
Sbjct: 1210 KEELEEQIAKKREQLAKEAGAKRQKLKEEYEGKLRVIYEELVSERSKNKELMNQNNQLSQ 1269

Query: 4308 KVTS----NTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVA 4363
            KV       T  K   +R +   ++ +E+  Q  Q + T  P++ +  E  +   E  ++
Sbjct: 1270 KVKLLEGVTTKQKKDIERVKQMEEKLKELERQSKQSEETDNPKVIESYEDKIKALEKEIS 1329

Query: 4364 KQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE 4398
              K         +E+  K+T  E    E   +T++
Sbjct: 1330 NLKDRNNNGEKVQELLHKVTYLEGELKERSVETEK 1364


>SB_33085| Best HMM Match : Trypsin (HMM E-Value=0)
          Length = 537

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 45/163 (27%), Positives = 62/163 (38%), Gaps = 24/163 (14%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           CR TG P PE  W  N R I               H + I     +D GV TCVA+N  G
Sbjct: 118 CRSTGNPIPEFKWTKNGRVIH------------VGHVINIARSFKTDEGVYTCVAQNGRG 165

Query: 473 ET-AFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPI 531
            T +    ++++     +           +V     +  N  A G P P I+W+K   P 
Sbjct: 166 FTNSVSSTVSIVYYSPRIQQPLQNDTFVEDVSRNFRLYCN--ATGNPRPMISWRKREDP- 222

Query: 532 IPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
                 R   +G   TL + R    +   Y CTA N  GS  +
Sbjct: 223 -----GRDFVNGPELTLRMSRDSKGN---YTCTATNDRGSVTS 257



 Score = 41.9 bits (94), Expect = 0.012
 Identities = 45/183 (24%), Positives = 72/183 (39%), Gaps = 26/183 (14%)

Query: 4633 IVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGD 4692
            ++ E   I  +C+  G P+P  +W K  ++I              + + I+ +F  DEG 
Sbjct: 107  VINETDPILLTCRSTGNPIPEFKWTKNGRVIHVG-----------HVINIARSFKTDEGV 155

Query: 4693 YKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFK--TQITSKIKP 4750
            Y CVA N  G  T +    V+    +  +    PL++    E     F+     T   +P
Sbjct: 156  YTCVAQNGRG-FTNSVSSTVSIVYYSPRIQ--QPLQNDTFVEDVSRNFRLYCNATGNPRP 212

Query: 4751 TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             I W +      E P    ++ G    L +     +  G +TC AT   G V TS   V+
Sbjct: 213  MISWRKR-----EDPGRDFVN-GPELTLRMS---RDSKGNYTCTATNDRGSV-TSIVGVI 262

Query: 4811 KSK 4813
              K
Sbjct: 263  DMK 265



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 12/105 (11%)

Query: 469 NKSGETAFQCRLNVIEKEQVVAPKFVERF-STLNVREGEPVVLNARAVGTPTPRITWQKD 527
           +K+   A    L V  KE  ++P       ++L + E +P++L  R+ G P P   W K+
Sbjct: 74  SKAKSLAHNDLLPVYRKELRLSPHNTTATPASLVINETDPILLTCRSTGNPIPEFKWTKN 133

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGST 572
           G          IH       ++I R+  +D   Y C AQN  G T
Sbjct: 134 G--------RVIHV---GHVINIARSFKTDEGVYTCVAQNGRGFT 167



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 13/84 (15%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            +P   T TP+ L+++E       CR     +     +W  NG+ +  G            
Sbjct: 95   SPHNTTATPASLVINETDPILLTCR--STGNPIPEFKWTKNGRVIHVGH----------- 141

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHG 3639
            ++ I   ++ D G+YTC A N  G
Sbjct: 142  VINIARSFKTDEGVYTCVAQNGRG 165



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 11/83 (13%)

Query: 263 VSPPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTT 322
           +SP      P +  + E        + +GNP P   W KNG R+I          H    
Sbjct: 94  LSPHNTTATPASLVINETDPILLTCRSTGNPIPEFKWTKNG-RVI----------HVGHV 142

Query: 323 LRVRNTQKSDSGHYTLLAENPNG 345
           + +  + K+D G YT +A+N  G
Sbjct: 143 INIARSFKTDEGVYTCVAQNGRG 165


>SB_35648| Best HMM Match : I-set (HMM E-Value=8.5e-05)
          Length = 181

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 45/174 (25%), Positives = 76/174 (43%), Gaps = 23/174 (13%)

Query: 4532 RLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINS 4591
            +L  +V G  P +V W  +G  +    + ++ + DG+  L+I+    +DSG+Y+ +  N+
Sbjct: 22   KLQLRVFGFPPPNVTW--SGPALSHS-KPRVNQSDGS--LVIMRTEFRDSGEYKAIVKNA 76

Query: 4592 AGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPL 4651
             GE       VVS        KP   A    P +        +   + +  +C  +G P 
Sbjct: 77   VGEVVVRTFLVVSQGV-----KPMFYATPDRPWLA-------IERSKTLPLTCGAMGVPS 124

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVT 4705
            P V+WY     IK      +  T +  T+ +S  +   EG+Y C A N  G V+
Sbjct: 125  PIVEWYHNGSPIKSG----VGGTKNNKTVTLS--WGSLEGNYLCRARNIFGVVS 172



 Score = 41.5 bits (93), Expect = 0.016
 Identities = 43/163 (26%), Positives = 66/163 (40%), Gaps = 17/163 (10%)

Query: 410 RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
           +   RV G P P VTW  +   +    + K  VN+S   +L+I      DSG    + +N
Sbjct: 22  KLQLRVFGFPPPNVTW--SGPALS---HSKPRVNQSDG-SLVIMRTEFRDSGEYKAIVKN 75

Query: 470 KSGETAFQCRLNVIEKEQVVAPKFVERFST--LNVREGEPVVLNARAVGTPTPRITWQKD 527
             GE   +  L V    Q V P F        L +   + + L   A+G P+P + W  +
Sbjct: 76  AVGEVVVRTFLVV---SQGVKPMFYATPDRPWLAIERSKTLPLTCGAMGVPSPIVEWYHN 132

Query: 528 GVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
           G PI      +    G  +   +  +  S    Y C A+N+ G
Sbjct: 133 GSPI------KSGVGGTKNNKTVTLSWGSLEGNYLCRARNIFG 169



 Score = 40.7 bits (91), Expect = 0.028
 Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 12/125 (9%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRF-TTHIQNIEGLKDGQS 3166
            L I+ T+  DSG Y     N  G+  +   L     S+G KP F  T  +    ++  ++
Sbjct: 56   LVIMRTEFRDSGEYKAIVKNAVGEVVVRTFLVV---SQGVKPMFYATPDRPWLAIERSKT 112

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
                C  + V  P   +EWYHNG P++  + +    +   V L     +    G Y+CRA
Sbjct: 113  LPLTCGAMGVPSPI--VEWYHNGSPIK--SGVGGTKNNKTVTLSWGSLE----GNYLCRA 164

Query: 3227 YNKYG 3231
             N +G
Sbjct: 165  RNIFG 169



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/61 (42%), Positives = 29/61 (47%), Gaps = 7/61 (11%)

Query: 1611 VEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIVH 1670
            VEWYHN  P+KSG   T+ N    V L   S      G Y CRA N  G  V+  I I  
Sbjct: 127  VEWYHNGSPIKSGVGGTKNNK--TVTLSWGSL----EGNYLCRARNIFG-VVSKSIFIEQ 179

Query: 1671 S 1671
            S
Sbjct: 180  S 180



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 6/91 (6%)

Query: 266 PKIAQKPRNSKL-QEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           P+I  +P+  +     A  + Q+++ G P P VTW  +G  L +S         +  +L 
Sbjct: 3   PRIKDQPKAIEFGYHPAAKKLQLRVFGFPPPNVTW--SGPALSHSKPR---VNQSDGSLV 57

Query: 325 VRNTQKSDSGHYTLLAENPNGCIVTSGYLAV 355
           +  T+  DSG Y  + +N  G +V   +L V
Sbjct: 58  IMRTEFRDSGEYKAIVKNAVGEVVVRTFLVV 88



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 3971 QPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFTPIYDFGY 4030
            +P  + T  +   ++   +T    C    +G P+  VEW+ NG P+  K+      +   
Sbjct: 93   KPMFYATPDRPWLAIERSKTLPLTC--GAMGVPSPIVEWYHNGSPI--KSGVGGTKNNKT 148

Query: 4031 VAMNFGWVYPEDSGEYLCRATNLYGM 4056
            V +++G +     G YLCRA N++G+
Sbjct: 149  VTLSWGSL----EGNYLCRARNIFGV 170


>SB_23794| Best HMM Match : ig (HMM E-Value=3.1e-07)
          Length = 175

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 13/130 (10%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P F    +D++ ++N      C      D  +   W HNG+ + T S    +     V+ 
Sbjct: 6    PAFMDITADIVANKNEDVSLPCT--STGDLPITTTWSHNGQVVQTSSSHSNL-----VLS 58

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQL-PSHFKSGTESIQKLE 3676
             + G     AG Y C  TN  G  + +  L+VKG   + +  Q+ P   ++ T+ I  +E
Sbjct: 59   HVNG---SQAGSYNCTVTNSRGSNSRTTYLRVKGGGSVKVFSQVSPGQGETRTQQIMHIE 115

Query: 3677 ETLHKREEIT 3686
               H   E T
Sbjct: 116  --YHVTSEFT 123



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 8/89 (8%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTT 3782
            GD  +   W HNG+   T S  H+        L + ++    AG Y C  TN  GS + T
Sbjct: 31   GDLPITTTWSHNGQVVQTSSS-HS-------NLVLSHVNGSQAGSYNCTVTNSRGSNSRT 82

Query: 3783 AKITCSAKRDIVLESQLPQGMSGEKIKEL 3811
              +       + + SQ+  G    + +++
Sbjct: 83   TYLRVKGGGSVKVFSQVSPGQGETRTQQI 111



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 16/53 (30%), Positives = 28/53 (52%)

Query: 2829 SYVSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDKNIYFDTQHPQGK 2881
            S+ +L ++H     +G Y C  TNS+GS + +  LR  G  ++   +Q   G+
Sbjct: 51   SHSNLVLSHVNGSQAGSYNCTVTNSRGSNSRTTYLRVKGGGSVKVFSQVSPGQ 103


>SB_2033| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 995

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 18/70 (25%), Positives = 35/70 (50%)

Query: 268 IAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRN 327
           + + P++ +L+ G     +    G P P   W+K+    +     + +T   + +L + N
Sbjct: 161 VLEFPKSQRLERGQSQVIRCSAEGYPTPHYQWYKDWNPTVLDYSDDRLTLLPNGSLLISN 220

Query: 328 TQKSDSGHYT 337
            Q+SDSG+YT
Sbjct: 221 VQESDSGNYT 230



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 40/175 (22%), Positives = 73/175 (41%), Gaps = 18/175 (10%)

Query: 3062 EGQIAHYEASLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGTY 3121
            + Q+    A   PT       +W  N   ++ S    T+   G +++     + +DSG Y
Sbjct: 174  QSQVIRCSAEGYPTPHYQWYKDW--NPTVLDYSDDRLTLLPNGSLLIS--NVQESDSGNY 229

Query: 3122 SCRATN-----KWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPV 3176
            +CR T      +  + + ++++      +    R +T + +  G   G    FECT    
Sbjct: 230  TCRITQLDEVGRPREEQKNIEVLVYGPPRVDLSRSSTVVYSYIGNLRGDK--FECTFWGY 287

Query: 3177 DDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYG 3231
              P M +   H    +  +T++K  +  G V +    T + D G+Y CRA N+ G
Sbjct: 288  PIPKMSM---HRSGAVLKNTKVKDRTITGHVTV----TSDEDFGDYECRASNELG 335



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 19/159 (11%)

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSST--LFVQSKASLQLESQHESALQ-KIQQLED 1826
            L +K +  +D G Y C+       A TS    LFV+   SL+ + +HE+ ++  I+ +  
Sbjct: 85   LVIKSIEVKDGGYYKCKG------AKTSKLFHLFVECFQSLR-DVRHENGIKDNIKSVHK 137

Query: 1827 SSRYQRREDVEVA-VNQAPRFITQLNGPT--KLSEGQSAHYECRIEPYPDPNMRVEWY-- 1881
             + +   + +  + +++    +  L  P   +L  GQS    C  E YP P+   +WY  
Sbjct: 138  HNLHLALKRIHKSNLSKLFHAVVVLEFPKSQRLERGQSQVIRCSAEGYPTPH--YQWYKD 195

Query: 1882 FNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920
            +N  VL       T    G  +L I  V   DSG YTC+
Sbjct: 196  WNPTVLDYSDDRLTLLPNG--SLLISNVQESDSGNYTCR 232



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 11/128 (8%)

Query: 1811 ESQHESALQKIQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLS---EGQSAHYEC 1866
            ES   +   +I QL++  R  + ++++EV V   PR     +     S     +   +EC
Sbjct: 223  ESDSGNYTCRITQLDEVGRPREEQKNIEVLVYGPPRVDLSRSSTVVYSYIGNLRGDKFEC 282

Query: 1867 RIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLG 1926
                YP P M +  + +G VL++  + +     G     +     ED G+Y C+A N LG
Sbjct: 283  TFWGYPIPKMSM--HRSGAVLKNT-KVKDRTITGH----VTVTSDEDFGDYECRASNELG 335

Query: 1927 QAVSSIRL 1934
             A   ++L
Sbjct: 336  NATHIVQL 343



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 15/33 (45%), Positives = 20/33 (60%)

Query: 2171 ILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAG 2203
            +  T  ED G Y C+A+N+LG A +   LK AG
Sbjct: 315  VTVTSDEDFGDYECRASNELGNATHIVQLKQAG 347



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 42/181 (23%), Positives = 65/181 (35%), Gaps = 11/181 (6%)

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
            ++E  K + +  GQ+    C   G P P  QWYK                    +L IS 
Sbjct: 161  VLEFPKSQRLERGQSQVIRCSAEGYPTPHYQWYKDWNPTVLDYSDDRLTLLPNGSLLISN 220

Query: 4685 AFPEDEGDYKC--VAYNSAGRVTVAAK---LKVTQPDQADNLPALTPLRDIVVYEGQPAQ 4739
                D G+Y C     +  GR     K   + V  P + D   + T +    +   +  +
Sbjct: 221  VQESDSGNYTCRITQLDEVGRPREEQKNIEVLVYGPPRVDLSRSSTVVYS-YIGNLRGDK 279

Query: 4740 FKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAA 4799
            F+        P +   R GA++  T        G+  V     T +ED G + CRA+   
Sbjct: 280  FECTFWGYPIPKMSMHRSGAVLKNTKVKDRTITGHVTV-----TSDEDFGDYECRASNEL 334

Query: 4800 G 4800
            G
Sbjct: 335  G 335


>SB_43971| Best HMM Match : I-set (HMM E-Value=1.7e-09)
          Length = 240

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 8/105 (7%)

Query: 2630 PEMFVDTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGA 2689
            P    D  ++ AP FT+ L S   + E   V +      R  PN  + W    V  T+G+
Sbjct: 140  PSTSWDLNIKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPN--VTW----VNKTSGS 193

Query: 2690 RLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             +      G  TLS+  ++   +G+Y C+A N +G    T  I I
Sbjct: 194  PV--AHGTGNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDITI 236



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 11/125 (8%)

Query: 1815 ESALQKIQQLEDSSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDP 1874
            +S L KI+    SS        ++ +  AP F + L+    ++E       C     P P
Sbjct: 124  KSYLVKIRT-SSSSPLSPSTSWDLNIKVAPAFTSSLSSSRDVAENDDVTVTCSASGRPAP 182

Query: 1875 NMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSI 1932
            N  V W    K   S   + T N    A L +L +    +G Y C+AIN++G+      I
Sbjct: 183  N--VTWV--NKTSGSPVAHGTGN----ATLSLLKIQRHQAGVYQCQAINDVGRGAITQDI 234

Query: 1933 RLNVQ 1937
             +NVQ
Sbjct: 235  TINVQ 239



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 11/88 (12%)

Query: 489 VAPKFVERFSTL-NVREGEPVVLNARAVGTPTPRITW--QKDGVPIIPNPELRIHTDGGA 545
           VAP F    S+  +V E + V +   A G P P +TW  +  G P+        H  G A
Sbjct: 150 VAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNVTWVNKTSGSPV-------AHGTGNA 202

Query: 546 STLDIPRAKASDAAWYQCTAQNVAGSTA 573
            TL + + +   A  YQC A N  G  A
Sbjct: 203 -TLSLLKIQRHQAGVYQCQAINDVGRGA 229



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 8/87 (9%)

Query: 390 LAPQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           +AP F   +   RDV E       C  +GRP P VTW +N        +   + + +GN 
Sbjct: 150 VAPAFTSSLSSSRDVAENDDVTVTCSASGRPAPNVTW-VNKT------SGSPVAHGTGNA 202

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETA 475
            L +  +    +GV  C A N  G  A
Sbjct: 203 TLSLLKIQRHQAGVYQCQAINDVGRGA 229



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 12/98 (12%)

Query: 3695 PRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRPFATGSRVHTLNDFGF 3752
            P FT  +  + DV E   V   C     G P   + W +  +G P A G+        G 
Sbjct: 152  PAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNVTWVNKTSGSPVAHGT--------GN 201

Query: 3753 IALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAK 3790
              L +  I    AG Y C+A N  G    T  IT + +
Sbjct: 202  ATLSLLKIQRHQAGVYQCQAINDVGRGAITQDITINVQ 239



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/132 (21%), Positives = 54/132 (40%), Gaps = 13/132 (9%)

Query: 1409 ILESQHPSGLEKIQYL-----EDTSRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVH 1463
            ++E ++ S +++  YL       +S    +   D ++ + P F +   S  +V E   V 
Sbjct: 112  VVEIRNASAVDEKSYLVKIRTSSSSPLSPSTSWDLNIKVAPAFTSSLSSSRDVAENDDVT 171

Query: 1464 FECKLEPVTDSNLKVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAEDSGIYTCRAVN 1523
              C        N+      +G PV         H  G   L ++ +    +G+Y C+A+N
Sbjct: 172  VTCSASGRPAPNVTWVNKTSGSPVA--------HGTGNATLSLLKIQRHQAGVYQCQAIN 223

Query: 1524 LVGTDEVSCRLT 1535
             VG   ++  +T
Sbjct: 224  DVGRGAITQDIT 235



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/127 (22%), Positives = 49/127 (38%), Gaps = 9/127 (7%)

Query: 3786 TCSAKRDIVLESQLPQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKS-HTVEES 3844
            +CS   +I   S + +     KI+      +S +   +  +   P F + + S   V E+
Sbjct: 108  SCSGVVEIRNASAVDEKSYLVKIRTSSSSPLSPSTSWDLNIKVAPAFTSSLSSSRDVAEN 167

Query: 3845 EGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYIC 3904
            + V   C    +  P   + W       P  H        G  +L +L +    +G Y C
Sbjct: 168  DDVTVTCSASGRPAPN--VTWVNKTSGSPVAH------GTGNATLSLLKIQRHQAGVYQC 219

Query: 3905 RAVNDFG 3911
            +A+ND G
Sbjct: 220  QAINDVG 226



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 14/97 (14%)

Query: 1304 DITVMQAPQFSRALHNIETV-EGTNVHLECRLQPVGDQTMRVEWF--CNGKPIKTGHRFR 1360
            D+ +  AP F+ +L +   V E  +V + C     G     V W    +G P+       
Sbjct: 145  DLNIKVAPAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNVTWVNKTSGSPV------- 195

Query: 1361 PAYEFDYVALDLLSVYPEDSGVYTCQATNQLGE-AVT 1396
             A+      L LL +    +GVY CQA N +G  A+T
Sbjct: 196  -AHGTGNATLSLLKIQRHQAGVYQCQAINDVGRGAIT 231



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 15/102 (14%)

Query: 1707 ITQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR--NGVPIEASNRLTTMH 1763
            I  AP FT  +   R VAEN            G P   V W+   +G P+         H
Sbjct: 148  IKVAPAFTSSLSSSRDVAENDDVTVTCSAS--GRPAPNVTWVNKTSGSPVA--------H 197

Query: 1764 DFGYVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQ 1803
              G   L++  +    +G Y C+AIN++G  A+T   T+ VQ
Sbjct: 198  GTGNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDITINVQ 239


>SB_29801| Best HMM Match : Collagen (HMM E-Value=3.2e-12)
          Length = 182

 Score = 42.3 bits (95), Expect = 0.009
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
           AP+ +     LN+     VVLN    G P+  +TW K G   +P    R   D G   L 
Sbjct: 94  APRVIIAPQKLNIDSSATVVLNCSVSGNPSAPVTWSKIG-GSLPRNRSR---DDGRGGLV 149

Query: 550 IPRAKASDAAWYQCTA 565
           I  A++SDA  Y+C +
Sbjct: 150 IRDARSSDAGLYECAS 165



 Score = 41.1 bits (92), Expect = 0.021
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 4/83 (4%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P   +  Q +N+ S   V L+  V+G     V W K G  +    RN+   +DG   L+I
Sbjct: 95   PRVIIAPQKLNIDSSATVVLNCSVSGNPSAPVTWSKIGGSLP---RNRS-RDDGRGGLVI 150

Query: 4574 LEAYPQDSGKYECVAINSAGEAR 4596
             +A   D+G YEC ++    ++R
Sbjct: 151  RDARSSDAGLYECASVGGLYKSR 173



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 4/71 (5%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRV 325
           P++   P+   +   A       +SGNP   VTW K G  L  +   +         L +
Sbjct: 95  PRVIIAPQKLNIDSSATVVLNCSVSGNPSAPVTWSKIGGSLPRNRSRD----DGRGGLVI 150

Query: 326 RNTQKSDSGHY 336
           R+ + SD+G Y
Sbjct: 151 RDARSSDAGLY 161


>SB_3251| Best HMM Match : I-set (HMM E-Value=1.8e-07)
          Length = 147

 Score = 42.3 bits (95), Expect = 0.009
 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 13/123 (10%)

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D G Y C   NS G+        +SL    +  +       + PE   P    ++  G  
Sbjct: 16   DEGHYICRVANSNGDYVFTEWAKLSLQNPSETHQFSRPIITSQPEY--PEVHTVL--GGT 71

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            +   C  +G P PT QWYK D L  P           EY  R  +   +D+G Y CVA N
Sbjct: 72   LRLYCDALGDPAPTFQWYKND-LPLP------DGDQREYCKR--DICADDQGRYMCVASN 122

Query: 4700 SAG 4702
            S+G
Sbjct: 123  SSG 125



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 41/154 (26%), Positives = 61/154 (39%), Gaps = 35/154 (22%)

Query: 323 LRVRNTQKSDSGHYTLLAENPNGCIVTSGY--LAVESPTESYVQDQRSQYITDTQQRETE 380
           LRV+N  K D GHY     N NG  V + +  L++++P+E++   Q S+ I  +Q     
Sbjct: 7   LRVKNVSKLDEGHYICRVANSNGDYVFTEWAKLSLQNPSETH---QFSRPIITSQ----- 58

Query: 381 ERIEISEKALAPQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
                      P++ +V        G   R  C   G P P   W+ ND  + D    + 
Sbjct: 59  -----------PEYPEV----HTVLGGTLRLYCDALGDPAPTFQWYKNDLPLPDGDQREY 103

Query: 441 LVNESGNHALMITNVTLSDSGVVTCVARNKSGET 474
              +          +   D G   CVA N SG T
Sbjct: 104 CKRD----------ICADDQGRYMCVASNSSGST 127



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 16/133 (12%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQ--CRL---NVIEKEQVVAPKFVER--FSTLNV 502
           L + NV+  D G   C   N +G+  F    +L   N  E  Q   P    +  +  ++ 
Sbjct: 7   LRVKNVSKLDEGHYICRVANSNGDYVFTEWAKLSLQNPSETHQFSRPIITSQPEYPEVHT 66

Query: 503 REGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQ 562
             G  + L   A+G P P   W K+ +P+ P+ + R +        DI    A D   Y 
Sbjct: 67  VLGGTLRLYCDALGDPAPTFQWYKNDLPL-PDGDQREYCKR-----DIC---ADDQGRYM 117

Query: 563 CTAQNVAGSTATR 575
           C A N +GST +R
Sbjct: 118 CVASNSSGSTESR 130



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 16/90 (17%)

Query: 1976 EKPQFGKPI--KNAEVTEGHPVHLEATLT----PVNDPTMRVEWYCNGRPVQQGHRFKTT 2029
            E  QF +PI     E  E H V L  TL      + DP    +WY N  P+  G + +  
Sbjct: 46   ETHQFSRPIITSQPEYPEVHTV-LGGTLRLYCDALGDPAPTFQWYKNDLPLPDGDQRE-- 102

Query: 2030 YDFGYVALDILYAYAEDTGTYMCKATNAVG 2059
                Y   DI    A+D G YMC A+N+ G
Sbjct: 103  ----YCKRDIC---ADDQGRYMCVASNSSG 125



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 22/113 (19%)

Query: 3824 PIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD 3883
            PI+++ P++    + HTV     +R  C  +   DP    +WY+N   LP G +      
Sbjct: 53   PIITSQPEYP---EVHTVLGGT-LRLYC--DALGDPAPTFQWYKNDLPLPDGDQRE---- 102

Query: 3884 MGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPRG 3936
              +   DI    A+D G Y+C A N  G   ++ T        + +++QVPRG
Sbjct: 103  --YCKRDIC---ADDQGRYMCVASNSSGSTESRPT-------RVFVRHQVPRG 143



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 9/55 (16%)

Query: 2802 DPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKATNSKGS 2856
            DP    +W+ N+ PLP G + +      Y   DI     +D G Y C A+NS GS
Sbjct: 81   DPAPTFQWYKNDLPLPDGDQRE------YCKRDIC---ADDQGRYMCVASNSSGS 126


>SB_56336| Best HMM Match : Ag332 (HMM E-Value=5.1)
          Length = 366

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 55/227 (24%), Positives = 96/227 (42%), Gaps = 21/227 (9%)

Query: 4216 PWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNE 4275
            P  +E  Q +  E E ++    ++  +++G ++  P+L+  V +EP+ E     + K+ E
Sbjct: 90   PVEEEPKQEEPVEEEQKQEEPVKEEPKQEGQVEEEPKLEEPVEEEPKQEEPVEEEPKQEE 149

Query: 4276 EYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK-SMAQRYEDNLDQTEEVTE 4334
             +     E + E V +ES++       AI     TS    K    Q  E+   Q E V E
Sbjct: 150  PF-----EEQKEAVAEESKVDAPV---AID----TSGVYEKPKQEQPVEEKSKQEEPVEE 197

Query: 4335 QRVQKK-VTQKPRIPDPSESTVHGKEV--HVAKQKQTQKEVVGDKEITRKITSTETTEIE 4391
            +  QK+ V ++P+    S      +E+     KQ+   +E    +E   K    E  E+ 
Sbjct: 198  EPKQKELVGEEPKTRRTSRRRTKQEEIVEEEPKQEGPVEEETRQEEPDEK--EREQEELV 255

Query: 4392 HKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFDGEP 4438
             +   +E  VE   K  +P     K +       E+ + E + DGEP
Sbjct: 256  EEEPKKEEPVEEETKQEEPVEEEPKQEEA---VDEEPKKEEQVDGEP 299


>SB_49916| Best HMM Match : ig (HMM E-Value=8.5e-06)
          Length = 465

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 11/79 (13%)

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAA 559
           + ++EG+ + L+  A GTP P++TW+K+G+ I+ N    I+T        I         
Sbjct: 14  IKLKEGDSISLDCTASGTPAPKVTWRKNGL-ILSNQS--IYT--------ITITTRYQYG 62

Query: 560 WYQCTAQNVAGSTATRARL 578
            Y C A N+AG TA + ++
Sbjct: 63  NYTCEASNIAGKTAWQGQI 81



 Score = 39.9 bits (89), Expect = 0.049
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 266 PKIAQKPRNS--KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITT 317
           PK+ + P +   KL+EG         SG P P+VTW KNG  L N + + I  T
Sbjct: 3   PKLNKSPPDKIIKLKEGDSISLDCTASGTPAPKVTWRKNGLILSNQSIYTITIT 56



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 19/132 (14%)

Query: 391 APQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNH 448
           AP+  K   D+ +   EG     DC  +G P P+VTW    R+     N  IL N+S   
Sbjct: 2   APKLNKSPPDKIIKLKEGDSISLDCTASGTPAPKVTW----RK-----NGLILSNQS--- 49

Query: 449 ALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPV 508
              IT  T    G  TC A N +G+TA+Q ++    + QV   + V   +T++       
Sbjct: 50  IYTITITTRYQYGNYTCEASNIAGKTAWQGQI----QSQVFPEENVTTITTVSPPSAGST 105

Query: 509 VLNARAVGTPTP 520
           V + R V  P P
Sbjct: 106 V-STRQVKQPPP 116



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 4110 PPVFVSLPDAVT-VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGMYHF 4167
            P +  S PD +  ++EG+     C  +G P P+V W  NG  + N S Y +T    Y +
Sbjct: 3    PKLNKSPPDKIIKLKEGDSISLDCTASGTPAPKVTWRKNGLILSNQSIYTITITTRYQY 61



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 14/105 (13%)

Query: 4623 PEIIEPLKDKIVA--EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTL 4680
            P++ +   DKI+   EG +I   C   G P P V W K   ++              YT+
Sbjct: 3    PKLNKSPPDKIIKLKEGDSISLDCTASGTPAPKVTWRKNGLILSNQSI---------YTI 53

Query: 4681 RISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
             I+  +    G+Y C A N AG+     +++ +Q    +N+  +T
Sbjct: 54   TITTRY--QYGNYTCEASNIAGKTAWQGQIQ-SQVFPEENVTTIT 95



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 13/82 (15%)

Query: 2783 IVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEED 2842
            I  KEGD+I  +C    S  P  K+ W  N   L + + Y  T         IT  Y+  
Sbjct: 14   IKLKEGDSISLDCTA--SGTPAPKVTWRKNGLILSNQSIYTIT---------ITTRYQY- 61

Query: 2843 SGIYTCKATNSKGSATTSGSLR 2864
             G YTC+A+N  G     G ++
Sbjct: 62   -GNYTCEASNIAGKTAWQGQIQ 82



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 11/72 (15%)

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSG 4582
            + +  G  + LD   +GT    V W KNG          IL     YT+ I   Y    G
Sbjct: 14   IKLKEGDSISLDCTASGTPAPKVTWRKNG---------LILSNQSIYTITITTRY--QYG 62

Query: 4583 KYECVAINSAGE 4594
             Y C A N AG+
Sbjct: 63   NYTCEASNIAGK 74


>SB_25723| Best HMM Match : Vicilin_N (HMM E-Value=0.0045)
          Length = 2506

 Score = 41.9 bits (94), Expect = 0.012
 Identities = 31/170 (18%), Positives = 81/170 (47%), Gaps = 3/170 (1%)

Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDN 4325
            +Q    K+ E++  ++++ ++EQV +  + RE   Q  I  ++++     + + +R ED 
Sbjct: 140  KQESDLKRREQWQKEMKQKKDEQVDEREKQREKQRQEKIMREQMSRKIKLRIVQKRSED- 198

Query: 4326 LDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITST 4385
             D+ +E    + +KK  +K R     +       + +A  ++ Q + +   E  R+    
Sbjct: 199  -DKRQESNHNK-RKKSMKKIREEKMKDQWKRRCSISLAHLERKQMKEMQRLERRRQNIER 256

Query: 4386 ETTEIEHKAQTQERVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFD 4435
             T+ ++  ++ Q+ V+E  +K  +  ++ + ++     +H + + E E +
Sbjct: 257  RTSTVQEHSEKQQAVLEQCLKTRRNTLYQEFLKAEEFMQHLREKKERELN 306


>SB_43939| Best HMM Match : I-set (HMM E-Value=1.3e-14)
          Length = 84

 Score = 41.5 bits (93), Expect = 0.016
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 11/91 (12%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQW-YKGDKLIKPSKYFQMSRTADEYTLR 4681
            P+II+P  D+ + EG+ +  SC   G P+P V W + G +L   S   ++S         
Sbjct: 3    PKIIQPPTDRTLNEGETLILSCYPGGFPVPYVTWRFNGTRLAANSSVLEIS--------D 54

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            +  A     G Y CVA N AG  T  A + +
Sbjct: 55   VKRAM--HHGTYTCVATNLAGSDTADAFITI 83



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 11/87 (12%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           PK ++  +   + EGE ++L+    G P P +TW+ +G  +  N          +S L+I
Sbjct: 3   PKIIQPPTDRTLNEGETLILSCYPGGFPVPYVTWRFNGTRLAAN----------SSVLEI 52

Query: 551 PRAK-ASDAAWYQCTAQNVAGSTATRA 576
              K A     Y C A N+AGS    A
Sbjct: 53  SDVKRAMHHGTYTCVATNLAGSDTADA 79



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 1/50 (2%)

Query: 266 PKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRL-INSNKHEI 314
           PKI Q P +  L EG          G P P VTW  NG RL  NS+  EI
Sbjct: 3   PKIIQPPTDRTLNEGETLILSCYPGGFPVPYVTWRFNGTRLAANSSVLEI 52


>SB_1939| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1646

 Score = 41.5 bits (93), Expect = 0.016
 Identities = 36/175 (20%), Positives = 80/175 (45%), Gaps = 10/175 (5%)

Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYY 4278
            ++  Q ++ E E +K  EE ++  +      R   + +  K+ + + ++  +R++ +E  
Sbjct: 155  EKEKQRKQLEVEKQKRLEEERIRSQNEERKRREREQKEREKQQKLDMEKEERRRRQQEEE 214

Query: 4279 NKLQELENEQ--VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQR 4336
             K +E E ++  V KE + RE   +  I   +    T      Q+Y   +    +  +++
Sbjct: 215  KKRREEEEKRKKVEKEKQEREKAAKKNIKRQQQQQRTDQ----QQYPREIPPRFQKMKRQ 270

Query: 4337 VQKKVTQKPRIPDPSESTVHGKEVHVAK-QKQTQKEVVGDKEITRKITSTETTEI 4390
             Q++  Q P +P P+ +   G    + K Q + Q++ VG K+   +  S E  ++
Sbjct: 271  QQQQQLQTPNLPPPAPT---GSPAQLNKFQSKPQQQPVGKKKDPNRFASKEYADL 322



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 36/187 (19%), Positives = 82/187 (43%), Gaps = 7/187 (3%)

Query: 4235 FEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESR 4294
            FE++ V + + V     + KPK  K+   E  Q  + K+ E+   +L+E   E+  KE +
Sbjct: 102  FEQQAVKKGKAVSVPVAKPKPKSKKQLLAE--QRRRAKEMEQIAMELEEKRKEEEEKEKQ 159

Query: 4295 LR--ESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSE 4352
             +  E   Q  +  +++ S    +   +R +   ++ +++  ++ +++  Q+       E
Sbjct: 160  RKQLEVEKQKRLEEERIRSQNEERKRREREQKEREKQQKLDMEKEERRRRQQEEEKKRRE 219

Query: 4353 STVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSKPPI 4412
                 K+V   K+KQ ++E    K I R+     T + ++  +   R  +   +  +  +
Sbjct: 220  EEEKRKKVE--KEKQ-EREKAAKKNIKRQQQQQRTDQQQYPREIPPRFQKMKRQQQQQQL 276

Query: 4413 FTKKMQP 4419
             T  + P
Sbjct: 277  QTPNLPP 283


>SB_49663| Best HMM Match : TolA (HMM E-Value=0.059)
          Length = 591

 Score = 41.5 bits (93), Expect = 0.016
 Identities = 40/205 (19%), Positives = 94/205 (45%), Gaps = 13/205 (6%)

Query: 4232 EKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIK 4291
            E+   +++ ++ Q  +  + + + + +KE   E ++   ++  E++  +L ELE E+  +
Sbjct: 196  ERERRQQEFIKEQKDVAVQQKAQQESLKETLQEQEKETIQQLEEDFKAQLNELEVEKAKE 255

Query: 4292 ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPS 4351
            ++ L E      +    V S  +   +  +Y+D L+      ++  ++++ +  R+ +  
Sbjct: 256  QTALEE------MKSFTVKSIILFSRVYSKYKDILEARNRQRKREREEELERIERVEEMQ 309

Query: 4352 ESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQ---TQERVVEGPVKPS 4408
              T   K +   +QK+ + E    KEI ++    E  + E K +    ++RV E  ++  
Sbjct: 310  RKTQEKKRIEEEEQKRKEAEEKKAKEIEQRRMEEEIKKEEEKKRKEAEEKRVKEEQIRLE 369

Query: 4409 KPPIFTKKMQPCRVFEHEQARFEVE 4433
            K     +K +     + E+AR E E
Sbjct: 370  K----ERKRKEADDRQREEARKEEE 390



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 43/192 (22%), Positives = 82/192 (42%), Gaps = 10/192 (5%)

Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIK----EPETEWQQSVKRKKN 4274
            +E  + +R E    KT E++++ + +       E K K I+    E E + ++  KRK+ 
Sbjct: 297  EELERIERVEEMQRKTQEKKRIEEEEQKRKEAEEKKAKEIEQRRMEEEIKKEEEKKRKEA 356

Query: 4275 EEYYNKLQE--LENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEV 4332
            EE   K ++  LE E+  KE+  R+         +K       K   +  E+ L +    
Sbjct: 357  EEKRVKEEQIRLEKERKRKEADDRQREEARKEEEEKRKREGEVKKRKEE-EERLVEARR- 414

Query: 4333 TEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEV--VGDKEITRKITSTETTEI 4390
             EQ  ++K+ ++ R  +        +E  + +++   KE     D+E  R+    E    
Sbjct: 415  KEQEEKRKLEEQKRKEEEDRRRKEAEEKRIKEEEARLKEERRSKDEEENRRKADEERKRK 474

Query: 4391 EHKAQTQERVVE 4402
            E +   + RVV+
Sbjct: 475  EQEEAERNRVVQ 486


>SB_41418| Best HMM Match : EGF_CA (HMM E-Value=0)
          Length = 3312

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 25/149 (16%)

Query: 4560 NKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAA 4619
            +++++     TL +      ++G Y C A N  G A    E +V         KP+    
Sbjct: 2870 DEVVQTADNGTLELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEY-------KPEL--- 2919

Query: 4620 NAPPEIIEPLKDKIVAEG-QAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEY 4678
                 + EP+  K+   G +   F C   G P P V+WY      +P  Y ++S    + 
Sbjct: 2920 -----LEEPISVKLALYGGKGARFPCLATGNPQPRVEWY-----YRP-LYSKLSFKLPDD 2968

Query: 4679 TLRISEAFPED---EGDYKCVAYNSAGRV 4704
              ++    P+D    G Y CVA NS GRV
Sbjct: 2969 DSQLVYIEPDDVMRSGFYYCVASNSRGRV 2997



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 11/125 (8%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIE-GLKDGQS 3166
            LE+   K +++G Y+C A N  G AE   ++  V+     KP       +++  L  G+ 
Sbjct: 2881 LELPSIKKSEAGMYTCEAANHKGSAESHYEV-IVE----YKPELLEEPISVKLALYGGKG 2935

Query: 3167 AHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVVLDIAYTQNHDSGEYVCRA 3226
            A F C  +   +P  ++EWY+  +P+      K   D   +V  I       SG Y C A
Sbjct: 2936 ARFPC--LATGNPQPRVEWYY--RPLYSKLSFKLPDDDSQLVY-IEPDDVMRSGFYYCVA 2990

Query: 3227 YNKYG 3231
             N  G
Sbjct: 2991 SNSRG 2995



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 406  GKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTC 465
            GK  RF C  TG P P V W+   R +    + K+  ++S    + I    +  SG   C
Sbjct: 2933 GKGARFPCLATGNPQPRVEWYY--RPLYSKLSFKLPDDDS--QLVYIEPDDVMRSGFYYC 2988

Query: 466  VARNKSGE-TAFQCRLNVIEKEQVV 489
            VA N  G   + + RL++++    V
Sbjct: 2989 VASNSRGRVVSEEGRLDILQSRGAV 3013



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 2/62 (3%)

Query: 2684 TLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWLLGE 2743
            T   G  +  T D G  TL + S++  ++G+YTC+A N  G A S   + +E +  LL E
Sbjct: 2865 TWRRGDEVVQTADNG--TLELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEYKPELLEE 2922

Query: 2744 SL 2745
             +
Sbjct: 2923 PI 2924



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 2/56 (3%)

Query: 2956 QGSRFKLTSDFGFVTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIE 3011
            +G     T+D G  TL+L  + + ++G+YTC+A N +G A +   V    K  L+E
Sbjct: 2868 RGDEVVQTADNG--TLELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEYKPELLE 2921



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/130 (20%), Positives = 50/130 (38%), Gaps = 6/130 (4%)

Query: 441  LVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
            +V  + N  L + ++  S++G+ TC A N  G       + V  K +++      + +  
Sbjct: 2872 VVQTADNGTLELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEYKPELLEEPISVKLALY 2931

Query: 501  NVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAW 560
                G+       A G P PR+ W     P+      ++  D  +  + I       + +
Sbjct: 2932 G---GKGARFPCLATGNPQPRVEWYYR--PLYSKLSFKL-PDDDSQLVYIEPDDVMRSGF 2985

Query: 561  YQCTAQNVAG 570
            Y C A N  G
Sbjct: 2986 YYCVASNSRG 2995



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 5/86 (5%)

Query: 266  PKIAQKPRNSKLQ--EGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTL 323
            P++ ++P + KL    G  A+F    +GNP+PRV W+    R + S     +   +   +
Sbjct: 2917 PELLEEPISVKLALYGGKGARFPCLATGNPQPRVEWY---YRPLYSKLSFKLPDDDSQLV 2973

Query: 324  RVRNTQKSDSGHYTLLAENPNGCIVT 349
             +       SG Y  +A N  G +V+
Sbjct: 2974 YIEPDDVMRSGFYYCVASNSRGRVVS 2999



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 14/43 (32%), Positives = 26/43 (60%)

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEP 3659
            LE+  + + +AG+YTC+A N  G A    ++ V+ +  ++ EP
Sbjct: 2881 LELPSIKKSEAGMYTCEAANHKGSAESHYEVIVEYKPELLEEP 2923



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 14/114 (12%)

Query: 1837 EVAVNQAPRFITQ-LNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRT 1895
            EV V   P  + + ++    L  G+ A + C     P P  RVEWY+  + L S   ++ 
Sbjct: 2910 EVIVEYKPELLEEPISVKLALYGGKGARFPCLATGNPQP--RVEWYY--RPLYSKLSFKL 2965

Query: 1896 SNDFGFAALDILTVYGED---SGEYTCKAINNLGQAVSSI-RLNV-QSKESIIR 1944
             +D       ++ +  +D   SG Y C A N+ G+ VS   RL++ QS+ ++ R
Sbjct: 2966 PDDDS----QLVYIEPDDVMRSGFYYCVASNSRGRVVSEEGRLDILQSRGAVPR 3015


>SB_24813| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1218

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 40/180 (22%), Positives = 77/180 (42%), Gaps = 10/180 (5%)

Query: 4224 YQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE 4283
            Y++   EL+K F +    ++Q + D     K  +  E E E+ + +K  +NE     ++ 
Sbjct: 327  YKQKIKELQKNFAK----EKQEIEDEYAHEKENIRAELENEFSEKIK-SENEALEETVKH 381

Query: 4284 LENE-QVIKESRLRESTHQYAIPGDKVTSNT----VAKSMAQRYEDNLDQTEEVTEQRVQ 4338
            L+ E   +KE +    T   ++    ++SN+    VAK      E  ++Q E    + ++
Sbjct: 382  LQGEINYLKEQKKELETKVQSLELKSLSSNSLDFRVAKEKISDLEQKVNQLEREKSRLLE 441

Query: 4339 KKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE 4398
            +    K R+ +         +  + KQ+Q  K     KE+T K    + T     A+ Q+
Sbjct: 442  ENAEFKVRMDELESEKSELSDSVLNKQRQLLKAEEDIKELTLKDQELDVTVELRGAEKQQ 501


>SB_1718| Best HMM Match : I-set (HMM E-Value=3.8e-07)
          Length = 1017

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 13/126 (10%)

Query: 3692 PNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH--NGRPFATGSRVHTLND 3749
            P  P FT  +  + DV E    +  C     G P+  + W +  +G P A G+       
Sbjct: 355  PIAPAFTPSLSRSHDVAENDDFNVTCSAS--GRPSPNVTWVNKTSGSPVAHGT------- 405

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIK 3809
             G   L +  I    AG Y CRATN  G  T T  +T + +     E  L     G  +K
Sbjct: 406  -GSAILSLLKIQRHQAGVYQCRATNDVGRGTITQDVTINVQYSSDEEYVLRTEAVG-AVK 463

Query: 3810 ELERGR 3815
              ER R
Sbjct: 464  HTERKR 469



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 8/94 (8%)

Query: 2641 APIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGLV 2700
            AP FT  L     + E     +      R  PN  + W    V  T+G+ +      G  
Sbjct: 357  APAFTPSLSRSHDVAENDDFNVTCSASGRPSPN--VTW----VNKTSGSPV--AHGTGSA 408

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
             LS+  ++   +G+Y C+ATN +G    T  + I
Sbjct: 409  ILSLLKIQRHQAGVYQCRATNDVGRGTITQDVTI 442



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 15/122 (12%)

Query: 1823 QLEDSSRYQRREDVEVAVNQ-----APRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMR 1877
            QL  S     R+   + VNQ     AP F   L+    ++E    +  C     P PN  
Sbjct: 332  QLAHSLHLHSRKLALLPVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPN-- 389

Query: 1878 VEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLN 1935
            V W    K   S   + T    G A L +L +    +G Y C+A N++G+      + +N
Sbjct: 390  VTWV--NKTSGSPVAHGT----GSAILSLLKIQRHQAGVYQCRATNDVGRGTITQDVTIN 443

Query: 1936 VQ 1937
            VQ
Sbjct: 444  VQ 445



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/102 (23%), Positives = 38/102 (37%), Gaps = 9/102 (8%)

Query: 3811 LERGRISDAPKEEPIVSTPPKFITQI-KSHTVEESEGVRFECRVEPKEDPKLRIEWYRNG 3869
            L   +++  P  +  +   P F   + +SH V E++     C    +  P   + W    
Sbjct: 339  LHSRKLALLPVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPN--VTWVNKT 396

Query: 3870 KLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFG 3911
               P  H        G   L +L +    +G Y CRA ND G
Sbjct: 397  SGSPVAH------GTGSAILSLLKIQRHQAGVYQCRATNDVG 432



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 20/92 (21%)

Query: 965  GYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDIIAESQHPGGLEKIQYLE 1024
            G   L++  +  H AG Y CRA N +G+ T + ++TI                  +QY  
Sbjct: 406  GSAILSLLKIQRHQAGVYQCRATNDVGRGTITQDVTI-----------------NVQYSS 448

Query: 1025 DASRYSKRTEE--EVKITQKPRFLGPLKGTNK 1054
            D   Y  RTE    VK T++ R+  PL+  +K
Sbjct: 449  D-EEYVLRTEAVGAVKHTERKRYFVPLRFMDK 479



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 10/93 (10%)

Query: 383 IEISEKAL--APQFV-KVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHK 439
           + ++++AL  AP F   + +  DV E       C  +GRP P VTW +N        +  
Sbjct: 347 LPVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPNVTW-VNKT------SGS 399

Query: 440 ILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            + + +G+  L +  +    +GV  C A N  G
Sbjct: 400 PVAHGTGSAILSLLKIQRHQAGVYQCRATNDVG 432



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 28/129 (21%), Positives = 53/129 (41%), Gaps = 16/129 (12%)

Query: 2099 PIEEEQPGQRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRY 2158
            P+ ++     P F  +L+   ++ E D  +  C       P++T  W +      +G   
Sbjct: 348  PVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPNVT--WVNK----TSGSP- 400

Query: 2159 RTTHDFGYVALDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRNIILDTQHPNGLE 2218
               H  G   L +L      +G Y C+ATN +G    T        +++ ++ Q+ +  E
Sbjct: 401  -VAHGTGSAILSLLKIQRHQAGVYQCRATNDVGRGTIT--------QDVTINVQYSSDEE 451

Query: 2219 KIRQLEAQG 2227
             + + EA G
Sbjct: 452  YVLRTEAVG 460



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 11/94 (11%)

Query: 480 LNVIEKEQVVAPKFVERFS-TLNVREGEPVVLNARAVGTPTPRITW--QKDGVPIIPNPE 536
           L V ++   +AP F    S + +V E +   +   A G P+P +TW  +  G P+     
Sbjct: 347 LPVNQQALPIAPAFTPSLSRSHDVAENDDFNVTCSASGRPSPNVTWVNKTSGSPV----- 401

Query: 537 LRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
              H  G A  L + + +   A  YQC A N  G
Sbjct: 402 --AHGTGSA-ILSLLKIQRHQAGVYQCRATNDVG 432



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 8/83 (9%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            P FT  L    ++ E    +  C     G P+  V W      +  +S     H  G   
Sbjct: 358  PAFTPSLSRSHDVAENDDFNVTCSAS--GRPSPNVTW------VNKTSGSPVAHGTGSAI 409

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            +++  ++    GVY CRA+N +G
Sbjct: 410  LSLLKIQRHQAGVYQCRATNDVG 432



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/83 (24%), Positives = 32/83 (38%), Gaps = 8/83 (9%)

Query: 3149 PRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHSTRIKTVSDFGFVV 3208
            P FT  +     + +    +  C+      P++      +G P+ H T        G  +
Sbjct: 358  PAFTPSLSRSHDVAENDDFNVTCSASGRPSPNVTWVNKTSGSPVAHGT--------GSAI 409

Query: 3209 LDIAYTQNHDSGEYVCRAYNKYG 3231
            L +   Q H +G Y CRA N  G
Sbjct: 410  LSLLKIQRHQAGVYQCRATNDVG 432


>SB_44749| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2250

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 10/103 (9%)

Query: 4405 VKPSKPPIFTKKMQPCRVFEHEQARFEVEFD----GEPLPLIKWYRENFPIKNSPDFQIH 4460
            ++  KPP+ T     C   +HE A  +V  D    G PLP+++W R    + N       
Sbjct: 1266 IRDRKPPVITCLGPDCNKTQHEIAESDVRLDCVAEGYPLPIVEWSRVGGVMPN-----YR 1320

Query: 4461 TFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEEK 4503
              S  S+ +++QV + D+ V+   A N  G      +L V EK
Sbjct: 1321 QLSNGSV-VLKQVKMTDTGVYQCQANNSQGGDIDRLSLHVAEK 1362



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 30/99 (30%), Positives = 43/99 (43%), Gaps = 8/99 (8%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARL--IPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYV 1768
            PV T    D    +++ A  + RL  +  G P   VEW R G  +    +L+     G V
Sbjct: 1272 PVITCLGPDCNKTQHEIAESDVRLDCVAEGYPLPIVEWSRVGGVMPNYRQLSN----GSV 1327

Query: 1769 ALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKAS 1807
             L  K V   D+G Y C+A N  G  +   +L V  K +
Sbjct: 1328 VL--KQVKMTDTGVYQCQANNSQGGDIDRLSLHVAEKCT 1364



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 7/76 (9%)

Query: 410  RFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARN 469
            R DC   G P P V W      +  +Y       +  N ++++  V ++D+GV  C A N
Sbjct: 1294 RLDCVAEGYPLPIVEWS-RVGGVMPNYR------QLSNGSVVLKQVKMTDTGVYQCQANN 1346

Query: 470  KSGETAFQCRLNVIEK 485
              G    +  L+V EK
Sbjct: 1347 SQGGDIDRLSLHVAEK 1362


>SB_26428| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 931

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 27/105 (25%), Positives = 53/105 (50%), Gaps = 6/105 (5%)

Query: 435 DYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
           D  +K  V    N+ ++I++    D+   T       G+   +   +++  +  VAPK  
Sbjct: 827 DNQYKGRVTLLENNTMVISSFKPVDAVTYTSKLLTHDGKNIQE---SLVAVKVAVAPKLK 883

Query: 495 ER--FSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPEL 537
           +      + ++EGE + L+  A GTP P++TW+K+G+ I+ N  +
Sbjct: 884 KSPPDKIIKLKEGESISLDCTASGTPAPKVTWRKNGL-ILSNQSI 927



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 2/47 (4%)

Query: 266 PKIAQKPRNS--KLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSN 310
           PK+ + P +   KL+EG         SG P P+VTW KNG  L N +
Sbjct: 880 PKLKKSPPDKIIKLKEGESISLDCTASGTPAPKVTWRKNGLILSNQS 926



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 6/64 (9%)

Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567
           L  +A G P+P+ITW K  G PI       +    G S L +   + A D   Y+C A N
Sbjct: 18  LQCKARGVPSPQITWYKPGGQPITAG----VSPISGGSQLQVTTTQDAGDYGQYKCRASN 73

Query: 568 VAGS 571
           + GS
Sbjct: 74  LLGS 77



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 1/58 (1%)

Query: 4099 EQVVEESKARCPPVFVSLPDAVT-VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGS 4155
            E +V    A  P +  S PD +  ++EGE     C  +G P P+V W  NG  + N S
Sbjct: 869  ESLVAVKVAVAPKLKKSPPDKIIKLKEGESISLDCTASGTPAPKVTWRKNGLILSNQS 926



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 29/113 (25%), Positives = 43/113 (38%), Gaps = 10/113 (8%)

Query: 236 FRESITKRYVGESDVQISTEIDRSLGPVSPPKIAQKPRNSKLQEG---ADAQFQVQLSGN 292
           F+++    Y      Q    ID+    +  P    K ++S+  EG    D   +    G 
Sbjct: 266 FQKAEDPTYANVPGQQEVIPIDQETTIIPDPAFIDKTKSSERTEGWVGYDVSLKCVTGGY 325

Query: 293 PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNG 345
           P P VTW        N+  H +    N T+  V   +  D G+YT  A N  G
Sbjct: 326 PTPTVTW-------SNATGHVLHEEVNLTSKYVFKVKDGDFGNYTCKATNKMG 371



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 377 RETEERIEISEKALAPQFVKVCQDRDVT--EGKMTRFDCRVTGRPYPEVTW 425
           +  +E +   + A+AP+  K   D+ +   EG+    DC  +G P P+VTW
Sbjct: 865 KNIQESLVAVKVAVAPKLKKSPPDKIIKLKEGESISLDCTASGTPAPKVTW 915


>SB_10779| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 897

 Score = 41.1 bits (92), Expect = 0.021
 Identities = 32/110 (29%), Positives = 45/110 (40%), Gaps = 8/110 (7%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  PP  +       V   + V   C V    DP L+I+WY NG  + S      +  MG
Sbjct: 308  VKDPPIIVLGPADQNVVTGDHVTMTCTVGG--DPPLKIKWYING--IDSSD----LATMG 359

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGEDFTKATISCKKLPDIILQNQVPR 3935
                  +   AE + +  C   ND G    KAT S ++   +  +N VPR
Sbjct: 360  QSRTSKITFRAEQTVKVECLVYNDLGRSSAKATASVQRRMPVTTRNMVPR 409



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 36/136 (26%), Positives = 51/136 (37%), Gaps = 14/136 (10%)

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
           D++V  G      C V G P  ++ W+IN     D      L     +    IT      
Sbjct: 320 DQNVVTGDHVTMTCTVGGDPPLKIKWYINGIDSSD------LATMGQSRTSKIT-FRAEQ 372

Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVER-----FSTLNVRE--GEPVVLNA 512
           +  V C+  N  G ++ +   +V  +  V     V R      +TLN     G  V L  
Sbjct: 373 TVKVECLVYNDLGRSSAKATASVQRRMPVTTRNMVPRKALITIATLNQTAGIGANVTLRC 432

Query: 513 RAVGTPTPRITWQKDG 528
            A GTP  +I W  DG
Sbjct: 433 SATGTPPMKIRWFIDG 448



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 77/350 (22%), Positives = 121/350 (34%), Gaps = 39/350 (11%)

Query: 4366 KQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVEGPVK-----PSKPPIFTKKMQPC 4420
            KQ+         +   IT+T    +  K +T       P K     P     FT  +   
Sbjct: 164  KQSLTSTAPTDSLPTHITATGM-HLSQKPETTATATASPTKVVANVPKTVLSFTNPLGNH 222

Query: 4421 RVFEHEQARFEVEFDGEPLPL-IKWYRENFPIKNSPDFQIHTFST---KSILIIRQVFVE 4476
             V      RF     G    + IKW      I + PD QI  ++    KS L +++   E
Sbjct: 223  TVAVGSSQRFVCHVKGTRKRVPIKWTWNGRIISDDPD-QIDIWNRPKRKSTLTLKKTKKE 281

Query: 4477 DSAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIV-PPSFTLTAQNVNVTSGQLVRLDT 4535
            DS ++   A    G         V+  +  G   +  PP   L   + NV +G  V +  
Sbjct: 282  DSGMYGCHA----GIGMIG----VDSIQMYGFLSVKDPPIIVLGPADQNVVTGDHVTMTC 333

Query: 4536 KVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEA 4595
             V G  P+ + W  NG      I +  L   G      +    + + K EC+  N  G +
Sbjct: 334  TVGGDPPLKIKWYING------IDSSDLATMGQSRTSKITFRAEQTVKVECLVYNDLGRS 387

Query: 4596 RCDAECVVS--LPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPT 4653
               A   V   +P T     P+ KA      I     ++    G  +   C   G P   
Sbjct: 388  SAKATASVQRRMPVTTRNMVPR-KAL-----ITIATLNQTAGIGANVTLRCSATGTPPMK 441

Query: 4654 VQWY-KGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
            ++W+  G          + S     +T  +++ + E     KC+A N  G
Sbjct: 442  IRWFIDGRYYDGEQNRGRESMYTSSFTFTVNKEYTE----VKCLAQNPYG 487



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 10/117 (8%)

Query: 2788 GDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYT 2847
            G N+   C+   +  P +KI WF + +    G + +      Y S   T T  ++     
Sbjct: 425  GANVTLRCSATGT--PPMKIRWFIDGRYY-DGEQNRGRESM-YTS-SFTFTVNKEYTEVK 479

Query: 2848 CKATNSKGSATTSGSLRCTGDKNIYFDTQHPQG-----KAGLEAVEQAEEARLAKGR 2899
            C A N  G    SG +R + +  +Y   ++PQG      A +EAV Q+   +   G+
Sbjct: 480  CLAQNPYGIDNRSGVIRPSEEGGLYGVWRNPQGDTVLFHADMEAVSQSPWDQFMPGK 536



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 37/157 (23%), Positives = 62/157 (39%), Gaps = 7/157 (4%)

Query: 3779 ATTTAKITCSAKRDIVLESQLPQGMS-GEKIKELERGRISDAPKEEPIVSTPPKFITQIK 3837
            +TT   +T +A  D +       GM   +K +       S       +  T   F   + 
Sbjct: 161  STTKQSLTSTAPTDSLPTHITATGMHLSQKPETTATATASPTKVVANVPKTVLSFTNPLG 220

Query: 3838 SHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYD--MGFVSLDILYVY 3895
            +HTV      RF C V+     ++ I+W  NG+++        +++      +L +    
Sbjct: 221  NHTVAVGSSQRFVCHVKGTR-KRVPIKWTWNGRIISDDPDQIDIWNRPKRKSTLTLKKTK 279

Query: 3896 AEDSGEYICRA-VNDFGEDFTK--ATISCKKLPDIIL 3929
             EDSG Y C A +   G D  +    +S K  P I+L
Sbjct: 280  KEDSGMYGCHAGIGMIGVDSIQMYGFLSVKDPPIIVL 316



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 47/186 (25%), Positives = 70/186 (37%), Gaps = 12/186 (6%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTG-RPYPEVTWFINDRQIRDDYNHKILVNESGNHA-LM 451
           F     +  V  G   RF C V G R    + W  N R I DD +   + N     + L 
Sbjct: 215 FTNPLGNHTVAVGSSQRFVCHVKGTRKRVPIKWTWNGRIISDDPDQIDIWNRPKRKSTLT 274

Query: 452 ITNVTLSDSGVVTCVAR-NKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
           +      DSG+  C A     G  + Q    +  K+    P  V   +  NV  G+ V +
Sbjct: 275 LKKTKKEDSGMYGCHAGIGMIGVDSIQMYGFLSVKDP---PIIVLGPADQNVVTGDHVTM 331

Query: 511 NARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAG 570
                G P  +I W  +G   I + +L   T G + T  I   +A      +C   N  G
Sbjct: 332 TCTVGGDPPLKIKWYING---IDSSDLA--TMGQSRTSKI-TFRAEQTVKVECLVYNDLG 385

Query: 571 STATRA 576
            ++ +A
Sbjct: 386 RSSAKA 391



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 3/71 (4%)

Query: 4001 GDPNMKVEWFFNGKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETK 4060
            G P MK+ WF +G+   +        +  Y + +F +   ++  E  C A N YG+D   
Sbjct: 436  GTPPMKIRWFIDGR--YYDGEQNRGRESMYTS-SFTFTVNKEYTEVKCLAQNPYGIDNRS 492

Query: 4061 AVIKTTGKPGI 4071
             VI+ + + G+
Sbjct: 493  GVIRPSEEGGL 503


>SB_50998| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 156

 Score = 40.7 bits (91), Expect = 0.028
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 11/86 (12%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P  +       VR GE + L     G PTP ++W K G           H+ GG +    
Sbjct: 71  PPEITPIQNTTVRAGETITLTCVLAGNPTPSVSWSKAGSG---------HSTGG-NVFTK 120

Query: 551 PRAKASDAAWYQCTAQN-VAGSTATR 575
             A  +D   Y CTA N V G+T TR
Sbjct: 121 AGATKADTGQYVCTAVNTVTGNTQTR 146



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 4604 SLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            SL   K+  +  T+    PPEI  P+++  V  G+ I  +C + G P P+V W K
Sbjct: 54   SLKRAKNS-RHHTQYNTDPPEIT-PIQNTTVRAGETITLTCVLAGNPTPSVSWSK 106


>SB_42485| Best HMM Match : Pkinase_Tyr (HMM E-Value=0)
          Length = 1565

 Score = 40.7 bits (91), Expect = 0.028
 Identities = 44/183 (24%), Positives = 80/183 (43%), Gaps = 22/183 (12%)

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G+Y+CVAINS G+        V + +++ K             ++ PL    VA G  
Sbjct: 336  DAGEYKCVAINSQGQGSATISLHVKVSSSEFK------------FLVTPLPFATVAFGAN 383

Query: 4640 IEFSCKIVGKPLPTVQWY-KGDKLIKPSKYFQ---MSRTADEYTLRISEAFPEDEGDYKC 4695
             E  C+   K   T  ++ K        KY +   + +  D Y++        D G Y+C
Sbjct: 384  YEMDCRTNDKNATTSLFFRKNPTFPSKEKYTEPKKLIKVGDIYSIIYFGV--NDFGAYQC 441

Query: 4696 VAYNSAGRVTVAAKLKV-TQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
             A N++G V    ++ +  +PD   ++  + P + +V+  GQ         S  + T++W
Sbjct: 442  RATNASGFVIQNVEVNLYGRPDVTPDV-KIVPDQAVVLTIGQ--HVNLTCISATQTTLKW 498

Query: 4755 LRE 4757
            L++
Sbjct: 499  LKQ 501



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 9/119 (7%)

Query: 4689 DEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKI 4748
            D G+YKCVA NS G+ +    L V +   ++    +TPL    V  G   +   +   K 
Sbjct: 336  DAGEYKCVAINSQGQGSATISLHV-KVSSSEFKFLVTPLPFATVAFGANYEMDCRTNDKN 394

Query: 4749 KPTIQWLREGALIPETPDF----QMIHEGN-NAVLLIGNTYEEDTGTFTCRATTAAGQV 4802
              T  + R+    P    +    ++I  G+  +++  G     D G + CRAT A+G V
Sbjct: 395  ATTSLFFRKNPTFPSKEKYTEPKKLIKVGDIYSIIYFG---VNDFGAYQCRATNASGFV 450



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 8/88 (9%)

Query: 480 LNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRI 539
           LNV EK ++V+PK      T+ VR  E    +  A G P P++ W + G          +
Sbjct: 907 LNVPEKAKIVSPKS----KTVLVRPEEHFNQSCHASGNPVPKVMWMRPG----KAGTKVL 958

Query: 540 HTDGGASTLDIPRAKASDAAWYQCTAQN 567
            T  G++ L I +    D A Y C A N
Sbjct: 959 STGQGSALLVIDKMSKDDIANYTCNATN 986



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 36/144 (25%), Positives = 53/144 (36%), Gaps = 10/144 (6%)

Query: 3108 LEILGTKTTDSGTYSCRATNKWGQAEISVKLECVDKSKGQKPRFTTHIQNIEGLKDGQSA 3167
            L I G +  D+G Y C A N  GQ   ++ L    K    + +F         +  G + 
Sbjct: 327  LVIRGVEGADAGEYKCVAINSQGQGSATISLHV--KVSSSEFKFLVTPLPFATVAFGANY 384

Query: 3168 HFECTVVPVDDPDMKIEWYHNGQPMRHS----TRIKTVSDFGFVVLDIAYTQNHDSGEYV 3223
              +C     +D +     +    P   S    T  K +   G  +  I Y   +D G Y 
Sbjct: 385  EMDCR---TNDKNATTSLFFRKNPTFPSKEKYTEPKKLIKVG-DIYSIIYFGVNDFGAYQ 440

Query: 3224 CRAYNKYGEDFTRATINCYGKGGV 3247
            CRA N  G       +N YG+  V
Sbjct: 441  CRATNASGFVIQNVEVNLYGRPDV 464



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 19/40 (47%), Positives = 25/40 (62%)

Query: 1902 AALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKES 1941
            A L I  V G D+GEY C AIN+ GQ  ++I L+V+   S
Sbjct: 325  AQLVIRGVEGADAGEYKCVAINSQGQGSATISLHVKVSSS 364



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)

Query: 2792 HFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYEEDSGIYTCKAT 2851
            HF  +   S +P  K+ W    +P  +GT+  ST   S + L I    ++D   YTC AT
Sbjct: 930  HFNQSCHASGNPVPKVMWM---RPGKAGTKVLSTGQGSAL-LVIDKMSKDDIANYTCNAT 985

Query: 2852 NSK 2854
            N K
Sbjct: 986  NYK 988



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 4/61 (6%)

Query: 3714 HFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRAT 3773
            HF+      G+P  ++ W    RP   G++V +    G   L ID +   D   YTC AT
Sbjct: 930  HFNQSCHASGNPVPKVMWM---RPGKAGTKVLSTGQ-GSALLVIDKMSKDDIANYTCNAT 985

Query: 3774 N 3774
            N
Sbjct: 986  N 986


>SB_10883| Best HMM Match : ig (HMM E-Value=7.00649e-43)
          Length = 1280

 Score = 40.7 bits (91), Expect = 0.028
 Identities = 35/125 (28%), Positives = 48/125 (38%), Gaps = 13/125 (10%)

Query: 450  LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
            L I +V   D G       +  GET F+     ++   V+A   V   + + V +     
Sbjct: 941  LTIKDVQPQDVGEYAMHLADDEGETTFEASKFTLD---VLAHPSVTH-ANITVNKTNTAE 996

Query: 510  LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
            L   A G P P +TW + G         +    G   TL     K SD   Y CTA N  
Sbjct: 997  LMCSATGNPKPNVTWTRSG---------KKDVLGTGETLTFSNVKISDGGCYVCTATNNI 1047

Query: 570  GSTAT 574
            GS A+
Sbjct: 1048 GSGAS 1052



 Score = 39.5 bits (88), Expect = 0.065
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 11/112 (9%)

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRI 522
           +T + +N   + A +  + + +    V P      + + V +    VL   A G PTP +
Sbjct: 254 ITLIIKNVQPQDAGEYAMRLSDDFGDVPPSVTH--ANITVNKTNTAVLMCSATGNPTPNV 311

Query: 523 TWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTAT 574
           TW + G       E  + T     TL     K SD   Y CTA N  GS A+
Sbjct: 312 TWTRSG------KEDVLWT---GETLTFRDVKISDGGCYVCTATNNIGSGAS 354



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 66/296 (22%), Positives = 105/296 (35%), Gaps = 47/296 (15%)

Query: 4517 TLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEA 4576
            ++T  N+ V       L    TG    +V W ++GKK        +L    T T   ++ 
Sbjct: 981  SVTHANITVNKTNTAELMCSATGNPKPNVTWTRSGKK-------DVLGTGETLTFSNVKI 1033

Query: 4577 YPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAE 4636
               D G Y C A N+ G       C+      + KP   T        I+          
Sbjct: 1034 --SDGGCYVCTATNNIGSGASGTVCL----TVRYKP-VHTNITGVESYIVRQC------- 1079

Query: 4637 GQAIEFSCKIVGKP-LPTVQWYKGDKLIKPSKYFQMSR-TADEYTLRISEAFPEDEGDYK 4694
            G AI  +C  VG+P L T   Y  + LI+ +          D   + +    P ++    
Sbjct: 1080 GAAISLTCSAVGEPQLITYHLYMDNLLIRKNINGMFHNILLDSVGIHLLTCVPINDAG-- 1137

Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
             V  N +  + V  KL            ++TPLR   V EG    F             W
Sbjct: 1138 -VGENRSVSMNVTEKLPTI---------SITPLR-ATVNEGSVVVFTCLAIGFQSFKNFW 1186

Query: 4755 LREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVV 4810
             ++G           + +G+ + L + +   +D+G +TC  T+  G    +A L V
Sbjct: 1187 KKDG-----------VFKGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDV 1231



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 33/178 (18%)

Query: 406 GKMTRFDCRVTGRPYPEVTW--FINDRQIRDDYN---HKILVNESGNHALMITNVTLSDS 460
           G      C   G P   +T+  ++++  IR + N   H IL++  G H  ++T V ++D+
Sbjct: 382 GAAISLTCSAVGEPQL-ITYHLYMDNLLIRKNINGMFHNILLDSVGIH--LLTCVPINDA 438

Query: 461 GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
           GV      N+S        +NV EK   ++   +   +T+N  EG  VV    A+G  + 
Sbjct: 439 GV----GENRS------VSINVTEKLPTISITHLR--ATVN--EGSVVVFTCLAIGFQSF 484

Query: 521 RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
           +  W+KDGV             G  S+L +      D+  Y C   +  G+T   A L
Sbjct: 485 KNFWKKDGV-----------FRGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASL 531



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%)

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+Y   + T +  TL I +  P+D G+Y     +  G  T  A  K T    A   P++T
Sbjct: 927  SRYSISTATFNPITLTIKDVQPQDVGEYAMHLADDEGETTFEAS-KFTLDVLAH--PSVT 983

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
               +I V +   A+     T   KP + W R G       D      G    L   N   
Sbjct: 984  H-ANITVNKTNTAELMCSATGNPKPNVTWTRSG-----KKDVL----GTGETLTFSNVKI 1033

Query: 4786 EDTGTFTCRATTAAG 4800
             D G + C AT   G
Sbjct: 1034 SDGGCYVCTATNNIG 1048



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 47/178 (26%), Positives = 76/178 (42%), Gaps = 33/178 (18%)

Query: 406  GKMTRFDCRVTGRPYPEVTW--FINDRQIRDDYN---HKILVNESGNHALMITNVTLSDS 460
            G      C   G P   +T+  ++++  IR + N   H IL++  G H  ++T V ++D+
Sbjct: 1080 GAAISLTCSAVGEPQL-ITYHLYMDNLLIRKNINGMFHNILLDSVGIH--LLTCVPINDA 1136

Query: 461  GVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTP 520
            GV      N+S        +NV EK   ++       +T+N  EG  VV    A+G  + 
Sbjct: 1137 GV----GENRS------VSMNVTEKLPTIS--ITPLRATVN--EGSVVVFTCLAIGFQSF 1182

Query: 521  RITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
            +  W+KDGV             G  S+L +      D+  Y C   +  G+T   A L
Sbjct: 1183 KNFWKKDGV-----------FKGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASL 1229



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 16/45 (35%), Positives = 23/45 (51%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM 4164
            +TV +   A   C  TG+PKP V W  +G   V G+   LT+  +
Sbjct: 987  ITVNKTNTAELMCSATGNPKPNVTWTRSGKKDVLGTGETLTFSNV 1031



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 14/34 (41%), Positives = 23/34 (67%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +L+++S+  DDSG YTC  T+  G  + TAS+ +
Sbjct: 500  SLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDV 533



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 14/34 (41%), Positives = 23/34 (67%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +L+++S+  DDSG YTC  T+  G  + TAS+ +
Sbjct: 1198 SLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDV 1231



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 13/107 (12%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  TG P P VTW    R  ++D      V  +G   L   +V +SD G   C A N  G
Sbjct: 301 CSATGNPTPNVTW---TRSGKED------VLWTG-ETLTFRDVKISDGGCYVCTATNNIG 350

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTP 518
             A       ++ + V     +    + NVR+ G  + L   AVG P
Sbjct: 351 SGASGIVCLTVQYKPVHTN--ITGVESYNVRQCGAAISLTCSAVGEP 395



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 9/63 (14%)

Query: 283  AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
            A+     +GNP+P VTW ++G       K +++ T    TL   N + SD G Y   A N
Sbjct: 995  AELMCSATGNPKPNVTWTRSG-------KKDVLGTGE--TLTFSNVKISDGGCYVCTATN 1045

Query: 343  PNG 345
              G
Sbjct: 1046 NIG 1048



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 11/81 (13%)

Query: 265 PPKIAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLR 324
           PP +     N  + +   A      +GNP P VTW ++G       K +++ T    TL 
Sbjct: 281 PPSVTHA--NITVNKTNTAVLMCSATGNPTPNVTWTRSG-------KEDVLWTGE--TLT 329

Query: 325 VRNTQKSDSGHYTLLAENPNG 345
            R+ + SD G Y   A N  G
Sbjct: 330 FRDVKISDGGCYVCTATNNIG 350



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 17/45 (37%), Positives = 26/45 (57%)

Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407
            ++ D  +L L SV  +DSG YTC  T+  G  + + +L VI K +
Sbjct: 1192 FKGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDVIYKPE 1236



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 17/42 (40%), Positives = 24/42 (57%)

Query: 1366 DYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407
            D  +L L SV  +DSG YTC  T+  G  + + +L VI K +
Sbjct: 497  DGSSLTLSSVGRDDSGNYTCNVTSTCGTTMKTASLDVIYKPE 538



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 17/117 (14%)

Query: 1690 QLEDTSKYQRHSAQDEVIT--QAPVFTMPM------KDIRVAENQAAHFEARLIPVGDPK 1741
            Q +D  +Y  H A DE  T  +A  FT+ +          +  N+    E      G+PK
Sbjct: 947  QPQDVGEYAMHLADDEGETTFEASKFTLDVLAHPSVTHANITVNKTNTAELMCSATGNPK 1006

Query: 1742 LRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
              V W R+G      + L T        L    V   D G Y C A N +G   + +
Sbjct: 1007 PNVTWTRSG----KKDVLGTGE-----TLTFSNVKISDGGCYVCTATNNIGSGASGT 1054



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 10/63 (15%)

Query: 413  CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
            C  TG P P VTW    R  + D      V  +G   L  +NV +SD G   C A N  G
Sbjct: 999  CSATGNPKPNVTW---TRSGKKD------VLGTG-ETLTFSNVKISDGGCYVCTATNNIG 1048

Query: 473  ETA 475
              A
Sbjct: 1049 SGA 1051


>SB_43084| Best HMM Match : ig (HMM E-Value=9.7e-23)
          Length = 960

 Score = 40.7 bits (91), Expect = 0.028
 Identities = 35/125 (28%), Positives = 48/125 (38%), Gaps = 13/125 (10%)

Query: 450 LMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVV 509
           L I +V   D G       +  GET F+     ++   V+A   V   + + V +     
Sbjct: 83  LTIKDVQPQDVGEYAMHLADDEGETTFEASKFTLD---VLAHPSVTH-ANITVNKTNTAE 138

Query: 510 LNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVA 569
           L   A G P P +TW + G         +    G   TL     K SD   Y CTA N  
Sbjct: 139 LMCSATGNPKPNVTWTRSG---------KKDVLGTGETLTFSNVKISDGGCYVCTATNNI 189

Query: 570 GSTAT 574
           GS A+
Sbjct: 190 GSGAS 194



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%)

Query: 4666 SKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALT 4725
            S+Y   + T +  TL I +  P+D G+Y     +  G  T  A  K T    A   P++T
Sbjct: 69   SRYSISTATFNPITLTIKDVQPQDVGEYAMHLADDEGETTFEAS-KFTLDVLAH--PSVT 125

Query: 4726 PLRDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYE 4785
               +I V +   A+     T   KP + W R G       D      G    L   N   
Sbjct: 126  H-ANITVNKTNTAELMCSATGNPKPNVTWTRSG-----KKDVL----GTGETLTFSNVKI 175

Query: 4786 EDTGTFTCRATTAAG 4800
             D G + C AT   G
Sbjct: 176  SDGGCYVCTATNNIG 190



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 16/45 (35%), Positives = 23/45 (51%)

Query: 4120 VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLTYDGM 4164
            +TV +   A   C  TG+PKP V W  +G   V G+   LT+  +
Sbjct: 129  ITVNKTNTAELMCSATGNPKPNVTWTRSGKKDVLGTGETLTFSNV 173



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 14/34 (41%), Positives = 23/34 (67%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +L+++S+  DDSG YTC  T+  G  + TAS+ +
Sbjct: 340  SLTLSSVGRDDSGNYTCNVTSTCGTTIKTASLDV 373



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 33/107 (30%), Positives = 43/107 (40%), Gaps = 13/107 (12%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  TG P P VTW    R  + D      V  +G   L  +NV +SD G   C A N  G
Sbjct: 141 CSATGNPKPNVTW---TRSGKKD------VLGTG-ETLTFSNVKISDGGCYVCTATNNIG 190

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVRE-GEPVVLNARAVGTP 518
             A       +  + V     +    + NVR+ G  + L   AVG P
Sbjct: 191 SGASGTVCLTVRYKPVHTN--ITGVESYNVRQCGAAISLTCSAVGEP 235



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 39/149 (26%), Positives = 64/149 (42%), Gaps = 27/149 (18%)

Query: 430 RQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVV 489
           R+  D   H I+++    H  ++T V ++D+GV      N+S        +NV EK   +
Sbjct: 250 RKNNDGVFHNIILDAVERH--LLTCVPINDAGV----GENRS------VSVNVTEKLPTI 297

Query: 490 APKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLD 549
           +   +   +T+N  EG  VV    A+G  + +  W+KDGV             G  S+L 
Sbjct: 298 SITHLR--ATVN--EGSVVVFTCLAIGFQSLKNFWKKDGV-----------FKGDGSSLT 342

Query: 550 IPRAKASDAAWYQCTAQNVAGSTATRARL 578
           +      D+  Y C   +  G+T   A L
Sbjct: 343 LSSVGRDDSGNYTCNVTSTCGTTIKTASL 371



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 9/63 (14%)

Query: 283 AQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAEN 342
           A+     +GNP+P VTW ++G       K +++ T    TL   N + SD G Y   A N
Sbjct: 137 AELMCSATGNPKPNVTWTRSG-------KKDVLGTGE--TLTFSNVKISDGGCYVCTATN 187

Query: 343 PNG 345
             G
Sbjct: 188 NIG 190



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 17/45 (37%), Positives = 26/45 (57%)

Query: 1363 YEFDYVALDLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKD 1407
            ++ D  +L L SV  +DSG YTC  T+  G  + + +L VI K +
Sbjct: 334  FKGDGSSLTLSSVGRDDSGNYTCNVTSTCGTTIKTASLDVIYKPE 378



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 17/117 (14%)

Query: 1690 QLEDTSKYQRHSAQDEVIT--QAPVFTMPM------KDIRVAENQAAHFEARLIPVGDPK 1741
            Q +D  +Y  H A DE  T  +A  FT+ +          +  N+    E      G+PK
Sbjct: 89   QPQDVGEYAMHLADDEGETTFEASKFTLDVLAHPSVTHANITVNKTNTAELMCSATGNPK 148

Query: 1742 LRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSS 1798
              V W R+G      + L T        L    V   D G Y C A N +G   + +
Sbjct: 149  PNVTWTRSG----KKDVLGTGE-----TLTFSNVKISDGGCYVCTATNNIGSGASGT 196


>SB_37145| Best HMM Match : ig (HMM E-Value=8e-07)
          Length = 323

 Score = 40.3 bits (90), Expect = 0.037
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 9/74 (12%)

Query: 4478 SAVFAAVAENRGGTAKCSANLVVEEKRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKV 4537
            S  F  V EN  GT K +A + +  K          PS T    N+ VT G LV L    
Sbjct: 212  SVQFTCVPENDVGTGK-NATVTINVK--------AAPSITFITANMTVTEGSLVNLQCNT 262

Query: 4538 TGTKPIDVYWLKNG 4551
            +G+ P++V W K G
Sbjct: 263  SGSLPLNVSWSKVG 276



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 18/163 (11%)

Query: 4570 TLLILEAYPQDSGKYECVAINSAGEARCDAECVV------SLPATKDKPKPQTKAANAPP 4623
            TL+I +  PQD+G+Y     +  GE   +A            P  +      T   N P 
Sbjct: 11   TLIIKDVQPQDAGEYAMTLADDGGETTSEASKFTLDVLGGDFPCRRFIDLRITARCNVPV 70

Query: 4624 EIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRIS 4683
                      VAEG  +   C   G   P +        I  +   Q+S T       IS
Sbjct: 71   TSHYQGSVMNVAEGSEVMLECNATGSS-PNI-------TIGRNGEAQLSTTGKHTFAAIS 122

Query: 4684 EAFPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTP 4726
                 +EG Y+C+ +N     TV +   +T   + +N   LTP
Sbjct: 123  R---REEGSYRCIVHNGGECPTVYSTTNITVNYKPEN-TTLTP 161


>SB_28081| Best HMM Match : ig (HMM E-Value=2e-08)
          Length = 293

 Score = 40.3 bits (90), Expect = 0.037
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           S S V  C A+NK+G       ++ IE E +  P    + S+L    G+   L+  A G 
Sbjct: 91  SGSNVFRCDAQNKAGSDTET--IDSIEIEGI--PVITSKQSSLTFNNGDQAFLHCNATGY 146

Query: 518 PTPRITWQKDG 528
           PTP +TW + G
Sbjct: 147 PTPNVTWIRLG 157



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 14/39 (35%), Positives = 20/39 (51%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            PV  S   ++T   G+ A   C  TG+P P V W+  G+
Sbjct: 120  PVITSKQSSLTFNNGDQAFLHCNATGYPTPNVTWIRLGD 158


>SB_21023| Best HMM Match : I-set (HMM E-Value=2e-07)
          Length = 175

 Score = 40.3 bits (90), Expect = 0.037
 Identities = 34/144 (23%), Positives = 56/144 (38%), Gaps = 13/144 (9%)

Query: 4622 PPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            PPEII P+++  V  G+ I  +C + G P P+V W K             S + + +T  
Sbjct: 34   PPEII-PIQNTTVRAGETITLTCAVAGNPTPSVFWSKAGS--------GHSTSGNVFTK- 83

Query: 4682 ISEAFPEDEGDYKCVAYNS-AGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQF 4740
             + A   D G Y C A N+  G                 ++ + +P + +    G   + 
Sbjct: 84   -ASATKADTGQYVCTAVNTVTGNTQTRTASTYVMVKYKPSILSKSPDQTVNETTGS-LKL 141

Query: 4741 KTQITSKIKPTIQWLREGALIPET 4764
                     PT  W R+G ++  T
Sbjct: 142  TCNSDGYPAPTSTWSRDGVVVSRT 165



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 11/75 (14%)

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           VR GE + L     G PTP + W K G           H+  G +      A  +D   Y
Sbjct: 45  VRAGETITLTCAVAGNPTPSVFWSKAGSG---------HSTSG-NVFTKASATKADTGQY 94

Query: 562 QCTAQN-VAGSTATR 575
            CTA N V G+T TR
Sbjct: 95  VCTAVNTVTGNTQTR 109



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 35/141 (24%), Positives = 55/141 (39%), Gaps = 14/141 (9%)

Query: 392 PQFVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALM 451
           P+ + + Q+  V  G+     C V G P P V W       +    H    + SGN    
Sbjct: 35  PEIIPI-QNTTVRAGETITLTCAVAGNPTPSVFW------SKAGSGH----STSGN-VFT 82

Query: 452 ITNVTLSDSGVVTCVARNK-SGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVL 510
             + T +D+G   C A N  +G T  +     +  +   +        T+N   G  + L
Sbjct: 83  KASATKADTGQYVCTAVNTVTGNTQTRTASTYVMVKYKPSILSKSPDQTVNETTGS-LKL 141

Query: 511 NARAVGTPTPRITWQKDGVPI 531
              + G P P  TW +DGV +
Sbjct: 142 TCNSDGYPAPTSTWSRDGVVV 162


>SB_42222| Best HMM Match : ig (HMM E-Value=2.1e-17)
          Length = 364

 Score = 40.3 bits (90), Expect = 0.037
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 458 SDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGT 517
           S S V  C A+NK+G       ++ IE E +  P    + S+L    G+   L+  A G 
Sbjct: 77  SGSNVFRCDAQNKAGSDTET--IDSIEIEGI--PVITSKQSSLTFNNGDQAFLHCNATGY 132

Query: 518 PTPRITWQKDG 528
           PTP +TW + G
Sbjct: 133 PTPNVTWIRLG 143



 Score = 38.7 bits (86), Expect = 0.11
 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 1/67 (1%)

Query: 4083 SIEKIREMEASWQVTPEQVVEESKARCPPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRV 4142
            SIE I   E    V  E   +  K    PV  S   ++T  EG+ A F C  TG P P V
Sbjct: 254  SIE-IEGKERKSNVRKENRRQGKKIEGIPVITSKLSSLTFNEGDQASFHCNATGFPTPNV 312

Query: 4143 MWLLNGN 4149
             W+  G+
Sbjct: 313  TWIRLGD 319



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 14/39 (35%), Positives = 20/39 (51%)

Query: 4111 PVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGN 4149
            PV  S   ++T   G+ A   C  TG+P P V W+  G+
Sbjct: 106  PVITSKQSSLTFNNGDQAFLHCNATGYPTPNVTWIRLGD 144



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 13/38 (34%), Positives = 19/38 (50%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDG 528
           P    + S+L   EG+    +  A G PTP +TW + G
Sbjct: 281 PVITSKLSSLTFNEGDQASFHCNATGFPTPNVTWIRLG 318


>SB_37828| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 358

 Score = 40.3 bits (90), Expect = 0.037
 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 4/75 (5%)

Query: 3840 TVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDS 3899
            T  E   V  EC      +P+  I+W R   +LPS     T+      SL I  V A D+
Sbjct: 279  TAVEGTSVSLECHFATSTNPE--IDWERLNGVLPSERA--TLSREPHSSLVIARVEASDA 334

Query: 3900 GEYICRAVNDFGEDF 3914
            G Y C A ND+G  F
Sbjct: 335  GRYKCYAANDYGSIF 349



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 39/133 (29%), Positives = 64/133 (48%), Gaps = 16/133 (12%)

Query: 441 LVNESGNHALMITNVTLSDSGVVTC-VARNKSGETAFQCRLNVIEKEQVVAPKFVERFST 499
           +VN S   A+++++VT  D+G   C      +G+TA   +L        +   F +R + 
Sbjct: 229 MVNSS---AILVSSVTGQDAGRYRCKTMATSTGDTAGLFKLGT-----PMNCVFKDRITA 280

Query: 500 LNVREGEPVVLNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDA 558
           +   EG  V L      +  P I W++ +GV  +P+    +  +  +S L I R +ASDA
Sbjct: 281 V---EGTSVSLECHFATSTNPEIDWERLNGV--LPSERATLSREPHSS-LVIARVEASDA 334

Query: 559 AWYQCTAQNVAGS 571
             Y+C A N  GS
Sbjct: 335 GRYKCYAANDYGS 347



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 3/76 (3%)

Query: 4630 KDKIVA-EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPE 4688
            KD+I A EG ++   C       P + W + + ++ PS+   +SR     +L I+     
Sbjct: 275  KDRITAVEGTSVSLECHFATSTNPEIDWERLNGVL-PSERATLSREPHS-SLVIARVEAS 332

Query: 4689 DEGDYKCVAYNSAGRV 4704
            D G YKC A N  G +
Sbjct: 333  DAGRYKCYAANDYGSI 348



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 4/76 (5%)

Query: 2781 NNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTYE 2840
            + I   EG ++  EC+   S +P  +I+W   N  LPS     S    S  SL I     
Sbjct: 276  DRITAVEGTSVSLECHFATSTNP--EIDWERLNGVLPSERATLSREPHS--SLVIARVEA 331

Query: 2841 EDSGIYTCKATNSKGS 2856
             D+G Y C A N  GS
Sbjct: 332  SDAGRYKCYAANDYGS 347



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 3702 KDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFH-NGRPFATGSRVHTLNDFGFIALDIDYI 3760
            KD I   EG  V  +C      +P   IDW   NG      S   TL+     +L I  +
Sbjct: 275  KDRITAVEGTSVSLECHFATSTNP--EIDWERLNG---VLPSERATLSREPHSSLVIARV 329

Query: 3761 YARDAGEYTCRATNKWGS 3778
             A DAG Y C A N +GS
Sbjct: 330  EASDAGRYKCYAANDYGS 347


>SB_26678| Best HMM Match : I-set (HMM E-Value=1e-07)
          Length = 563

 Score = 40.3 bits (90), Expect = 0.037
 Identities = 36/143 (25%), Positives = 55/143 (38%), Gaps = 10/143 (6%)

Query: 4575 EAYPQDSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIV 4634
            +  PQ+   +E  A N+ GE   D  C           KP T      P I  PL D   
Sbjct: 121  DGQPQER-VHEICARNNIGEIH-DHYCSDRYTTAAICKKPATGGFFGTPVIFSPLPDVDA 178

Query: 4635 AEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYK 4694
             E + I   C+ +G  +  + W   D L++       +R+ +   L IS       G ++
Sbjct: 179  YENETITLQCQAIGDAVIIIAWLHNDTLVQ-------NRSVNT-ALVISNIPLNMSGSWR 230

Query: 4695 CVAYNSAGRVTVAAKLKVTQPDQ 4717
            CVA N  G       + V +P +
Sbjct: 231  CVASNHLGSQNKTFYVDVKKPSE 253



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 11/83 (13%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            PV   PL ++D   E +T    C+ I  GD  + + W  N+ L+++ S  T        +
Sbjct: 167  PVIFSPLPDVD-AYENETITLQCQAI--GDAVIIIAWLHNDTLVQNRSVNT--------A 215

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + IS++     G + C ASN LG
Sbjct: 216  LVISNIPLNMSGSWRCVASNHLG 238



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 9/73 (12%)

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
           D D  E +     C+  G     + W  ND  ++         N S N AL+I+N+ L+ 
Sbjct: 175 DVDAYENETITLQCQAIGDAVIIIAWLHNDTLVQ---------NRSVNTALVISNIPLNM 225

Query: 460 SGVVTCVARNKSG 472
           SG   CVA N  G
Sbjct: 226 SGSWRCVASNHLG 238


>SB_10221| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 766

 Score = 40.3 bits (90), Expect = 0.037
 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 10/96 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I+  L D  V +G++I   C+  G  +  + W   + L++       +RT D  T  +
Sbjct: 589  PIILPSLPDVEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQ-------NRTKD--TALV 639

Query: 4683 SEAFP-EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
             +  P   +G +KCVA N  G+ T +  L VT P Q
Sbjct: 640  FDKVPLTAKGSWKCVASNHLGQDTKSFYLHVTNPVQ 675



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 10/93 (10%)

Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
            KR+   G    P    +  +V V  G+ +RL  + TG   I + WL N   VQ   ++  
Sbjct: 578  KRKADGGYFGTPIILPSLPDVEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQNRTKD-- 635

Query: 4563 LEEDGTYTLLILEAYPQDS-GKYECVAINSAGE 4594
                   T L+ +  P  + G ++CVA N  G+
Sbjct: 636  -------TALVFDKVPLTAKGSWKCVASNHLGQ 661



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 9/88 (10%)

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
           D +V +GK  R  C  TG     + W          +N+ ++ N + + AL+   V L+ 
Sbjct: 597 DVEVEKGKSIRLQCEATGDAVIYIAWL---------HNNTLVQNRTKDTALVFDKVPLTA 647

Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQ 487
            G   CVA N  G+      L+V    Q
Sbjct: 648 KGSWKCVASNHLGQDTKSFYLHVTNPVQ 675



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 1/47 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            P +  SLPD V VE+G+  R  C  TG     + WL N   + N ++
Sbjct: 589  PIILPSLPD-VEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQNRTK 634


>SB_10219| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 929

 Score = 40.3 bits (90), Expect = 0.037
 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 10/96 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I+  L D  V +G++I   C+  G  +  + W   + L++       +RT D  T  +
Sbjct: 752  PIILPSLPDVEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQ-------NRTKD--TALV 802

Query: 4683 SEAFP-EDEGDYKCVAYNSAGRVTVAAKLKVTQPDQ 4717
             +  P   +G +KCVA N  G+ T +  L VT P Q
Sbjct: 803  FDKVPLTAKGSWKCVASNHLGQDTKSFYLHVTDPVQ 838



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 10/93 (10%)

Query: 4503 KRRQGRGGIVPPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKI 4562
            KR+   G    P    +  +V V  G+ +RL  + TG   I + WL N   VQ   ++  
Sbjct: 741  KRKADGGYFGTPIILPSLPDVEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQNRTKD-- 798

Query: 4563 LEEDGTYTLLILEAYPQDS-GKYECVAINSAGE 4594
                   T L+ +  P  + G ++CVA N  G+
Sbjct: 799  -------TALVFDKVPLTAKGSWKCVASNHLGQ 824



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 9/88 (10%)

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
           D +V +GK  R  C  TG     + W          +N+ ++ N + + AL+   V L+ 
Sbjct: 760 DVEVEKGKSIRLQCEATGDAVIYIAWL---------HNNTLVQNRTKDTALVFDKVPLTA 810

Query: 460 SGVVTCVARNKSGETAFQCRLNVIEKEQ 487
            G   CVA N  G+      L+V +  Q
Sbjct: 811 KGSWKCVASNHLGQDTKSFYLHVTDPVQ 838



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 1/47 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSR 4156
            P +  SLPD V VE+G+  R  C  TG     + WL N   + N ++
Sbjct: 752  PIILPSLPD-VEVEKGKSIRLQCEATGDAVIYIAWLHNNTLVQNRTK 797


>SB_29692| Best HMM Match : ig (HMM E-Value=5.4e-12)
          Length = 567

 Score = 39.9 bits (89), Expect = 0.049
 Identities = 31/102 (30%), Positives = 43/102 (42%), Gaps = 13/102 (12%)

Query: 56  GDRQPITAGRPGEPSPPIFEQIFKNARFAQGGNAKFEGKL----RGNPTPVVSWTRKKAP 111
           G + PI  G  GEP PP+ +            N   +  L     GNP PVV+W R+   
Sbjct: 263 GPKGPI--GPKGEPGPPLTKPKITTGSPKSRANVSTKAWLPCVASGNPHPVVTWQRRNGS 320

Query: 112 LVECNKYSMRYNEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
           L +         E +G   L +  +   D+GEY C AR+  G
Sbjct: 321 LPQRRSKV----EMSG---LSVSHVTTADQGEYGCEARSIMG 355



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 17/156 (10%)

Query: 413 CRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSG 472
           C  +G P+P VTW    R+       +  V  SG   L +++VT +D G   C AR+  G
Sbjct: 302 CVASGNPHPVVTW---QRRNGSLPQRRSKVEMSG---LSVSHVTTADQGEYGCEARSIMG 355

Query: 473 ETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPII 532
                  L  I ++++     + +  T  +   EP+V+  +A G       WQ+    ++
Sbjct: 356 VEVVWTEL--IVQDRLRFTMKMPKQQTFYM--FEPIVVPCQAKG--AVGTIWQRKN-RMM 408

Query: 533 PNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
           P  + R   +G   TL +PRA   D+  Y C   N+
Sbjct: 409 PE-KARTLING---TLFLPRASPRDSGTYTCIVTNL 440



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 1/58 (1%)

Query: 4670 QMSRTADEYTLRISEAFPEDEGDYKCVAYN-SAGRVTVAAKLKVTQPDQADNLPALTP 4726
            + +RT    TL +  A P D G Y C+  N    R+T + ++ V  P    ++  L P
Sbjct: 410  EKARTLINGTLFLPRASPRDSGTYTCIVTNLLQRRITESVEISVLYPKSCHHIKQLRP 467


>SB_21223| Best HMM Match : I-set (HMM E-Value=2.8e-11)
          Length = 90

 Score = 39.9 bits (89), Expect = 0.049
 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 5/76 (6%)

Query: 505 GEPVVLNARAVGTPTPRITWQKDGVPIIP--NPELRIHTDGGASTLDIPRAKASDAAWYQ 562
           G  ++ +  A G PTP +TWQK+G    P   P +RI  +   ++L I   K  DA  YQ
Sbjct: 14  GSVLLWHCTATGYPTPVLTWQKNGQGFNPWWPPHIRILAN---NSLLINGVKREDAGSYQ 70

Query: 563 CTAQNVAGSTATRARL 578
           C A   + S A +A L
Sbjct: 71  CRATINSLSNAIQAVL 86



 Score = 38.3 bits (85), Expect = 0.15
 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 394 FVKVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMIT 453
           F +  QD  +  G +  + C  TG P P +TW  N +     +   I +    N++L+I 
Sbjct: 2   FTRTPQDTAIDLGSVLLWHCTATGYPTPVLTWQKNGQGFNPWWPPHIRI--LANNSLLIN 59

Query: 454 NVTLSDSGVVTCVARNKSGETAFQCRLNV 482
            V   D+G   C A   S   A Q  L V
Sbjct: 60  GVKREDAGSYQCRATINSLSNAIQAVLIV 88


>SB_33134| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2208

 Score = 39.9 bits (89), Expect = 0.049
 Identities = 46/184 (25%), Positives = 88/184 (47%), Gaps = 21/184 (11%)

Query: 4228 ETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQ-----SVKRKKNEEYYNKLQ 4282
            ET+L+K   E +  +         +LK +V KE ET+  Q     S+  K  +E   K+ 
Sbjct: 994  ETKLKKAVNETKRYESSS-----SQLKQQV-KELETDNLQRKQKLSLTEKDRDELERKIA 1047

Query: 4283 ELENEQVIKESRLRESTHQYAIP-----GDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRV 4337
            EL+   +  E R R++TH+ A        +++T+N  AK+     +  + Q  +   Q  
Sbjct: 1048 ELQ--AITSELRKRQATHEAANSKLSEDNERLTNNAAAKAQNIERDAIIQQLMDEKSQMS 1105

Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEV-VGDKEITRKITS-TETTEIEHKAQ 4395
            +K  +++  +     ++    E  ++ Q+  +KE+    KE+  KIT+ TE ++ + KA 
Sbjct: 1106 KKLQSKEDELATEKANSQKHTET-LSSQRAKEKELHTNIKELEAKITTLTEESQAKLKAS 1164

Query: 4396 TQER 4399
            + E+
Sbjct: 1165 SYEK 1168


>SB_20290| Best HMM Match : ig (HMM E-Value=2.9e-15)
          Length = 978

 Score = 39.9 bits (89), Expect = 0.049
 Identities = 38/149 (25%), Positives = 67/149 (44%), Gaps = 13/149 (8%)

Query: 1810 LESQHESALQKIQQLEDSSRYQRRED-VEVAVN-QAPRFITQLNGPTKLSEGQSAHYECR 1867
            ++S+      KIQ    ++ +Q  +  +E  +N QAP     +  P+ ++E  S    C+
Sbjct: 103  IKSKDGFGAHKIQCRVTANSFQTGQPPLETLLNVQAPISKLSVIVPSAVNESDSVRMTCQ 162

Query: 1868 IEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ 1927
             E  PDP     W FN K  + G      ND  +    +L+V+ +  G YTC A +  G 
Sbjct: 163  AEGSPDPKPTFRW-FNAKGEEIG------NDTFYT---VLSVHRDRPGPYTCLATDACGH 212

Query: 1928 A-VSSIRLNVQSKESIIRDSQHESALEKI 1955
               +++ L VQ K    + ++   A + +
Sbjct: 213  IHRANVTLTVQYKPDFTKLTKKSPAQDTV 241



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 11/102 (10%)

Query: 3826 VSTPPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMG 3885
            V  P   ++ I    V ES+ VR  C+ E   DPK    W+ N K    G+   T Y   
Sbjct: 136  VQAPISKLSVIVPSAVNESDSVRMTCQAEGSPDPKPTFRWF-NAKGEEIGN--DTFY--- 189

Query: 3886 FVSLDILYVYAEDSGEYICRAVNDFGE-DFTKATISCKKLPD 3926
                 +L V+ +  G Y C A +  G       T++ +  PD
Sbjct: 190  ----TVLSVHRDRPGPYTCLATDACGHIHRANVTLTVQYKPD 227


>SB_24046| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2848

 Score = 39.5 bits (88), Expect = 0.065
 Identities = 43/217 (19%), Positives = 92/217 (42%), Gaps = 6/217 (2%)

Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYY 4278
            DE  +    + E E+  +E + LQR+     R E   K ++  + E +Q ++R+K  E  
Sbjct: 1478 DEERRLIMEQQERERR-QEMEYLQREKEERLRVEEALKKLEREKEEERQRLEREKELEIE 1536

Query: 4279 NKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQ 4338
             +L +++ ++VI+  R R+   +     +K       + + +   +  ++ E    ++ +
Sbjct: 1537 RQL-KIKEKEVIRLQRERDEERRRREDEEKRIQMEKVEELKRIEREKEEELERQMREKEE 1595

Query: 4339 KKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE 4398
            +   QK    D  E     +    A++ + + E     E   +    E  E E + + +E
Sbjct: 1596 EMERQKQVFQDTLEQERRLRNDREAEEARRRLEEASRSEEYERQRQLELQEKERRNKEEE 1655

Query: 4399 RVVEGPVKPSKPPIFTKKMQPCRVFEHEQARFEVEFD 4435
              +    +  +  +  K+    R+FE E AR E E +
Sbjct: 1656 DNLLDAYRRKQEQLLEKE----RIFEEEMARRERELE 1688


>SB_33855| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 879

 Score = 39.1 bits (87), Expect = 0.086
 Identities = 30/132 (22%), Positives = 47/132 (35%), Gaps = 13/132 (9%)

Query: 448 HALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEP 507
           H L +  +      + TCV  N++G+     ++  +  ++  +   +    T+   EG  
Sbjct: 144 HGLFVLRLNTPGVTIFTCVPSNEAGDGLN--KIVTVTVKEFHSSVSIAPARTITTSEGSY 201

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           V +   A       I W KDGVP    P           TL  P         Y CT   
Sbjct: 202 VQMTCSASAVDLSSINWVKDGVPQAKGP-----------TLTFPSISRDQGGVYNCTVIE 250

Query: 568 VAGSTATRARLY 579
             GS +T   +Y
Sbjct: 251 GCGSASTDIAVY 262



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 1/51 (1%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSRYKL 4159
            P   V  P  +TV E +     C   G P P   W+   G+T+ +G  Y +
Sbjct: 12   PSSVVISPSCLTVTERDQVNLTCSADGTPPPTFTWISPQGHTVAHGPSYTI 62


>SB_18843| Best HMM Match : I-set (HMM E-Value=1e-07)
          Length = 339

 Score = 39.1 bits (87), Expect = 0.086
 Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 11/120 (9%)

Query: 1821 IQQLEDSSR-YQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVE 1879
            ++ ++ +SR Y   +  ++ + +AP F   L+    ++E +     C     P PN  V 
Sbjct: 227  VKIMDPTSRVYTALKAWDLTIREAPAFNPPLDRSRDVAEDKDFSITCSASGRPAPN--VT 284

Query: 1880 WYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQA--VSSIRLNVQ 1937
            W    K   S   + T N    A L +L +    +G Y C+AIN++G+      + +NVQ
Sbjct: 285  WV--NKTSGSPVAHGTGN----ATLSLLKIQRHQAGVYQCQAINDVGRGAITQDVTINVQ 338



 Score = 39.1 bits (87), Expect = 0.086
 Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 1691 LEDTSK-YQRHSAQDEVITQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR 1748
            ++ TS+ Y    A D  I +AP F  P+   R VAE++   F       G P   V W+ 
Sbjct: 230  MDPTSRVYTALKAWDLTIREAPAFNPPLDRSRDVAEDK--DFSITCSASGRPAPNVTWVN 287

Query: 1749 --NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGE-AVTSS-TLFVQ 1803
              +G P+         H  G   L++  +    +G Y C+AIN++G  A+T   T+ VQ
Sbjct: 288  KTSGSPVA--------HGTGNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDVTINVQ 338



 Score = 37.5 bits (83), Expect = 0.26
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 7/77 (9%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
           + RDV E K     C  +GRP P VTW +N        +   + + +GN  L +  +   
Sbjct: 259 RSRDVAEDKDFSITCSASGRPAPNVTW-VNKT------SGSPVAHGTGNATLSLLKIQRH 311

Query: 459 DSGVVTCVARNKSGETA 475
            +GV  C A N  G  A
Sbjct: 312 QAGVYQCQAINDVGRGA 328



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 15/128 (11%)

Query: 1274 DIVTDTQNEQAIEQIQLLEDAARRTKQVRE-DITVMQAPQFSRALHNIETV-EGTNVHLE 1331
            DI   T  ++ +  +++++  +R    ++  D+T+ +AP F+  L     V E  +  + 
Sbjct: 213  DIKRVTVQDERVYLVKIMDPTSRVYTALKAWDLTIREAPAFNPPLDRSRDVAEDKDFSIT 272

Query: 1332 CRLQPVGDQTMRVEWF--CNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATN 1389
            C     G     V W    +G P+        A+      L LL +    +GVY CQA N
Sbjct: 273  CSAS--GRPAPNVTWVNKTSGSPV--------AHGTGNATLSLLKIQRHQAGVYQCQAIN 322

Query: 1390 QLGE-AVT 1396
             +G  A+T
Sbjct: 323  DVGRGAIT 330



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 8/100 (8%)

Query: 2635 DTGVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKST 2694
            D  +++AP F   L     + E +   +      R  PN  + W    V  T+G+ +   
Sbjct: 244  DLTIREAPAFNPPLDRSRDVAEDKDFSITCSASGRPAPN--VTW----VNKTSGSPV--A 295

Query: 2695 FDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
               G  TLS+  ++   +G+Y C+A N +G    T  + I
Sbjct: 296  HGTGNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDVTI 335



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 14/122 (11%)

Query: 1955 IQYLEDDSRYKRAVQD-DSFVVEKPQFGKPI-KNAEVTEGHPVHLEATLTPVNDPTMRVE 2012
            ++ ++  SR   A++  D  + E P F  P+ ++ +V E     +  T +    P   V 
Sbjct: 227  VKIMDPTSRVYTALKAWDLTIREAPAFNPPLDRSRDVAEDKDFSI--TCSASGRPAPNVT 284

Query: 2013 WY--CNGRPVQQGHRFKTTYDFGYVALDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            W    +G PV  G         G   L +L       G Y C+A N VG    T  V ++
Sbjct: 285  WVNKTSGSPVAHGT--------GNATLSLLKIQRHQAGVYQCQAINDVGRGAITQDVTIN 336

Query: 2071 AK 2072
             +
Sbjct: 337  VQ 338



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 21/86 (24%), Positives = 35/86 (40%), Gaps = 8/86 (9%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            R+ P F  PL    ++ E +     C     G P   V W      +  +S     H  G
Sbjct: 248  REAPAFNPPLDRSRDVAEDKDFSITCSAS--GRPAPNVTW------VNKTSGSPVAHGTG 299

Query: 2433 YVSMTISHVRDEDEGVYMCRASNLLG 2458
              ++++  ++    GVY C+A N +G
Sbjct: 300  NATLSLLKIQRHQAGVYQCQAINDVG 325



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/91 (23%), Positives = 36/91 (39%), Gaps = 7/91 (7%)

Query: 4623 PEIIEPL-KDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLR 4681
            P    PL + + VAE +    +C   G+P P V W      +  +    ++      TL 
Sbjct: 251  PAFNPPLDRSRDVAEDKDFSITCSASGRPAPNVTW------VNKTSGSPVAHGTGNATLS 304

Query: 4682 ISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            + +      G Y+C A N  GR  +   + +
Sbjct: 305  LLKIQRHQAGVYQCQAINDVGRGAITQDVTI 335


>SB_11246| Best HMM Match : ig (HMM E-Value=7.5e-07)
          Length = 80

 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 11/75 (14%)

Query: 502 VREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
           VR GE + L     G PTP ++W K G           H+ GG +      A  +D   Y
Sbjct: 6   VRAGETITLTCAVAGNPTPSVSWSKAGSG---------HSTGG-NVFTKAGATKADTGQY 55

Query: 562 QCTAQN-VAGSTATR 575
            CTA N V G+  TR
Sbjct: 56  VCTAVNIVTGNIQTR 70


>SB_1675| Best HMM Match : ig (HMM E-Value=5.6e-05)
          Length = 964

 Score = 38.7 bits (86), Expect = 0.11
 Identities = 26/62 (41%), Positives = 32/62 (51%), Gaps = 9/62 (14%)

Query: 2672 PNLKIEWFKN-GVTL--TTGARLKSTFDFGL----VT--LSINSLRNDDSGIYTCKATNL 2722
            P LKI W+KN G+ +  T G   K TFD       VT  L+I  L N DSG+Y C  +  
Sbjct: 239  PGLKINWYKNTGLLIPGTEGVSWKITFDTDFDENRVTSKLNIAKLNNTDSGLYQCNVSTK 298

Query: 2723 LG 2724
             G
Sbjct: 299  FG 300



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 9/62 (14%)

Query: 2941 PDLKIEWYFNGKVL---EQGSRFKLTSDFGF----VT--LDLVDVYERDSGIYTCKAYNK 2991
            P LKI WY N  +L    +G  +K+T D  F    VT  L++  +   DSG+Y C    K
Sbjct: 239  PGLKINWYKNTGLLIPGTEGVSWKITFDTDFDENRVTSKLNIAKLNNTDSGLYQCNVSTK 298

Query: 2992 RG 2993
             G
Sbjct: 299  FG 300


>SB_43870| Best HMM Match : Pkinase_Tyr (HMM E-Value=0)
          Length = 869

 Score = 38.7 bits (86), Expect = 0.11
 Identities = 25/77 (32%), Positives = 31/77 (40%), Gaps = 4/77 (5%)

Query: 4636 EGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKC 4695
            EG   E  C   G P P + WYK D L  P    Q      +Y L I    P+  G Y C
Sbjct: 47   EGSKAELICDATGYPQPVIAWYK-DGLHYPG---QPKLGPFDYRLTIQGLNPDSAGKYMC 102

Query: 4696 VAYNSAGRVTVAAKLKV 4712
               N+ G  +    +KV
Sbjct: 103  NVTNAFGWESYTYSIKV 119



 Score = 37.9 bits (84), Expect = 0.20
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 4/64 (6%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I W+K+G+      +L   FD+    L+I  L  D +G Y C  TN  G    T S
Sbjct: 61   PQPVIAWYKDGLHYPGQPKL-GPFDY---RLTIQGLNPDSAGKYMCNVTNAFGWESYTYS 116

Query: 2732 IKIE 2735
            IK+E
Sbjct: 117  IKVE 120



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 4/56 (7%)

Query: 252 ISTEIDRSLGPVSPPKIAQKPRNS----KLQEGADAQFQVQLSGNPRPRVTWFKNG 303
           ++  +  +LG   PP+     + +    K QEG+ A+     +G P+P + W+K+G
Sbjct: 16  LTLSVGLTLGNTEPPQFKDLSKMNDIQRKYQEGSKAELICDATGYPQPVIAWYKDG 71



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 10/91 (10%)

Query: 67  GEPSPPIFEQIFK----NARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRY 122
           G   PP F+ + K      ++ +G  A+      G P PV++W +      +   Y  + 
Sbjct: 25  GNTEPPQFKDLSKMNDIQRKYQEGSKAELICDATGYPQPVIAWYK------DGLHYPGQP 78

Query: 123 NEQTGDVSLLIKQIGPGDEGEYTCTARNQYG 153
                D  L I+ + P   G+Y C   N +G
Sbjct: 79  KLGPFDYRLTIQGLNPDSAGKYMCNVTNAFG 109


>SB_35812| Best HMM Match : Atrophin-1 (HMM E-Value=0.23)
          Length = 4240

 Score = 38.7 bits (86), Expect = 0.11
 Identities = 36/156 (23%), Positives = 71/156 (45%), Gaps = 13/156 (8%)

Query: 4259 KEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSM 4318
            K P+ + Q+ +  K + +   K +E++   ++  S   +   +  +P DK T++T+A+  
Sbjct: 2568 KPPQEKTQERLNSKADTKKGLK-EEIKTTPIVSSSGQAKKNERKVLPKDKPTNDTLAEKK 2626

Query: 4319 AQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHV-AKQKQTQ----KEVV 4373
              + ED +++  E  E R  + ++     PDP+     GK+     K   TQ    + VV
Sbjct: 2627 VSKPEDTVEKKSE--EGRFSRFISSMLSEPDPAHP---GKDKEQDKKDDSTQVLPARMVV 2681

Query: 4374 GDKEITRKITSTETTEIEHKAQTQERVVEGPVKPSK 4409
             D++   K T+  T   +      + + EG  KP +
Sbjct: 2682 QDEKKEAKKTAENTW--KKNVSNPKTIPEGEHKPEE 2715


>SB_23775| Best HMM Match : Tropomyosin (HMM E-Value=0)
          Length = 442

 Score = 38.7 bits (86), Expect = 0.11
 Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 8/125 (6%)

Query: 4222 TQYQRTETELEKTFEER--QVLQRQGVIDHRP------ELKPKVIKEPETEWQQSVKRKK 4273
            TQ Q TE E +    ER  +VL+ +G  D         +    + +  E E Q     ++
Sbjct: 67   TQGQLTEAEKQADESERARKVLENRGASDEERLASLERQYNDALERTEEAEKQYEEISER 126

Query: 4274 NEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVT 4333
             +E  N+L+E E +    E+R++E   +  + G+ + S  +++  A   ED  +      
Sbjct: 127  LQELENELEEAEQKADAAEARVKELEEEVTLVGNNLRSLEISEGKASEREDTYENQIREL 186

Query: 4334 EQRVQ 4338
            E ++Q
Sbjct: 187  ETKLQ 191



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 33/148 (22%), Positives = 67/148 (45%), Gaps = 9/148 (6%)

Query: 4259 KEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSM 4318
            K  +T+ Q +   K+ +E     + LEN     E RL     QY    D +     A+  
Sbjct: 63   KLADTQGQLTEAEKQADESERARKVLENRGASDEERLASLERQY---NDALERTEEAEKQ 119

Query: 4319 AQRYEDNLDQTEEVTEQRVQKKVTQKPRIPD-PSESTVHG---KEVHVAKQKQTQKEVVG 4374
             +   + L + E   E+  QK    + R+ +   E T+ G   + + +++ K +++E   
Sbjct: 120  YEEISERLQELENELEEAEQKADAAEARVKELEEEVTLVGNNLRSLEISEGKASEREDTY 179

Query: 4375 DKEITRKITSTETTEIEHKAQTQERVVE 4402
            + +I R++  T+  + E +A+  E+ V+
Sbjct: 180  ENQI-REL-ETKLQDAEERAEKAEQKVQ 205


>SB_23345| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 903

 Score = 38.3 bits (85), Expect = 0.15
 Identities = 38/131 (29%), Positives = 68/131 (51%), Gaps = 17/131 (12%)

Query: 4218 YDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELK----PKVIKEPETEWQQSVK--- 4270
            YD++ + +R   + E+  +ER+  +R       PE K    PKV+ EP  E + +VK   
Sbjct: 519  YDDSWRGRRARRKAEEERKERERRERLEKKHSEPEKKTEEPPKVVVEPTVEKEPAVKVES 578

Query: 4271 RKKNEEYYN---KLQELENEQVIK----ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYE 4323
             K  EE  +   K ++   E+  K     +RLRE+T + +  GDK  S++  +S ++R+E
Sbjct: 579  EKTEEEPLDDEAKREKARQERAAKRAERRARLREATSEES--GDKGQSDSSDRS-SRRHE 635

Query: 4324 DNLDQTEEVTE 4334
            ++   + + TE
Sbjct: 636  ESDTSSSKDTE 646



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 29/126 (23%), Positives = 55/126 (43%), Gaps = 4/126 (3%)

Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYY 4278
            +E  + QR E E ++  +E +  +++    H+ E + K  +  +  W+    R+K EE  
Sbjct: 477  EEEERKQREEEERKQKEKEEEKKRKEEERKHKEEEEKKTEESYDDSWRGRRARRKAEE-E 535

Query: 4279 NKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQ 4338
             K +E       K S   + T +   P   V   TV K  A + E    + E + ++  +
Sbjct: 536  RKERERRERLEKKHSEPEKKTEE---PPKVVVEPTVEKEPAVKVESEKTEEEPLDDEAKR 592

Query: 4339 KKVTQK 4344
            +K  Q+
Sbjct: 593  EKARQE 598


>SB_50677| Best HMM Match : I-set (HMM E-Value=6.7e-11)
          Length = 87

 Score = 38.3 bits (85), Expect = 0.15
 Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 11/86 (12%)

Query: 491 PKFVERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDI 550
           P  +       +R GE + L     G PTP ++W K G               G +  + 
Sbjct: 2   PPGITPIQNTTIRAGETITLTCAVAGNPTPSVSWSKAG----------SGQSTGGNVFNE 51

Query: 551 PRAKASDAAWYQCTAQN-VAGSTATR 575
             A  +D   Y CTA N V+G+T T+
Sbjct: 52  AGATKADTGQYVCTAVNIVSGNTQTK 77



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYK 4658
            P  I P+++  +  G+ I  +C + G P P+V W K
Sbjct: 2    PPGITPIQNTTIRAGETITLTCAVAGNPTPSVSWSK 37



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 13/80 (16%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            P  + P+ N   +  G+ I L C +   G+PT  V W   G   + G     + + G   
Sbjct: 2    PPGITPIQNTT-IRAGETITLTCAVA--GNPTPSVSWSKAGSGQSTGGN--VFNEAG--- 53

Query: 1237 LDIIHATSADTGEYTVRAVN 1256
                 AT ADTG+Y   AVN
Sbjct: 54   -----ATKADTGQYVCTAVN 68


>SB_40656| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 492

 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 4528 GQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLILEAYP-QDSGKYEC 4586
            G+ V    +V+G +P + ++   G KV   + +  +E  G Y +LI++    +D GKY C
Sbjct: 217  GERVTRVCQVSG-EPFEGWYDPQGNKVTAQVDHVYVERRGPYHVLIIDGVTAEDGGKYTC 275

Query: 4587 VAINSAGEARCDAECVVSLPAT 4608
                 + +   +  CV   P T
Sbjct: 276  RGSFDSAQVGINVNCVSGTPKT 297



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 277 LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHY 336
           + EG        + G+P P+  W KNGQ +  ++    ++     +L ++    SDSG Y
Sbjct: 12  MAEGTTGIIFTTVRGHPPPKYIWTKNGQPINLADDRYTVSPSG--SLSIKGVTSSDSGEY 69

Query: 337 TL 338
           +L
Sbjct: 70  SL 71



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 4/76 (5%)

Query: 84  AQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMRYNEQTGDVSLLIKQIGPGDEGE 143
           A+G        +RG+P P   WT+   P+   N    RY       SL IK +   D GE
Sbjct: 13  AEGTTGIIFTTVRGHPPPKYIWTKNGQPI---NLADDRYTVSPSG-SLSIKGVTSSDSGE 68

Query: 144 YTCTARNQYGEAICSV 159
           Y+   R Q       +
Sbjct: 69  YSLNVRQQLASGFMKI 84


>SB_26233| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 463

 Score = 37.9 bits (84), Expect = 0.20
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 4323 EDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI 4382
            E + D+ EE  E++ +KK+TQK +   P +    G +   +KQ+    E   D +   K+
Sbjct: 205  ESDDDEEEEEEEEKEEKKLTQKKKGKTPEQKKTPGTKKAASKQRHPTDEKRKDGQ--EKV 262

Query: 4383 TSTETTEIEHKAQTQE 4398
               E  E+E    T+E
Sbjct: 263  EEKEKGEVEDAQTTEE 278


>SB_16822| Best HMM Match : I-set (HMM E-Value=1.3e-07)
          Length = 259

 Score = 37.9 bits (84), Expect = 0.20
 Identities = 37/120 (30%), Positives = 55/120 (45%), Gaps = 16/120 (13%)

Query: 1691 LEDTS-KYQRHSAQDEVITQAPVFTMPMKDIR-VAENQAAHFEARLIPVGDPKLRVEWLR 1748
            ++ TS KY    A +  I  AP F  P+   R VAE++   F       G P   V W+ 
Sbjct: 104  MDPTSYKYTALRAWNLTIRAAPAFNQPLDRSRDVAEDK--DFSITCSASGRPAPNVTWVN 161

Query: 1749 --NGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINEL-GEAVTSS-TLFVQS 1804
              +G P+         H  G   L++  +    +G Y C+AIN++  EA+T   T+ VQS
Sbjct: 162  KTSGSPVA--------HGTGSATLSLLKIQRHQAGVYQCQAINDVRREAITQDVTINVQS 213



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 10/114 (8%)

Query: 1827 SSRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKV 1886
            S +Y       + +  AP F   L+    ++E +     C     P PN  V W    K 
Sbjct: 108  SYKYTALRAWNLTIRAAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPN--VTWV--NKT 163

Query: 1887 LQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCKAINNL-GQAVS-SIRLNVQS 1938
              S   + T    G A L +L +    +G Y C+AIN++  +A++  + +NVQS
Sbjct: 164  SGSPVAHGT----GSATLSLLKIQRHQAGVYQCQAINDVRREAITQDVTINVQS 213



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/103 (24%), Positives = 43/103 (41%), Gaps = 8/103 (7%)

Query: 2638 VQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDF 2697
            ++ AP F   L     + E +   +      R  PN  + W    V  T+G+ +      
Sbjct: 121  IRAAPAFNQPLDRSRDVAEDKDFSITCSASGRPAPN--VTW----VNKTSGSPV--AHGT 172

Query: 2698 GLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIEDRHWL 2740
            G  TLS+  ++   +G+Y C+A N +     T  + I  + WL
Sbjct: 173  GSATLSLLKIQRHQAGVYQCQAINDVRREAITQDVTINVQSWL 215



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%)

Query: 391 APQFVK-VCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHA 449
           AP F + + + RDV E K     C  +GRP P VTW +N        +   + + +G+  
Sbjct: 124 APAFNQPLDRSRDVAEDKDFSITCSASGRPAPNVTW-VNKT------SGSPVAHGTGSAT 176

Query: 450 LMITNVTLSDSGVVTCVARN 469
           L +  +    +GV  C A N
Sbjct: 177 LSLLKIQRHQAGVYQCQAIN 196



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 21/83 (25%), Positives = 33/83 (39%), Gaps = 8/83 (9%)

Query: 2373 RQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFG 2432
            R  P F QPL    ++ E +     C     G P   V W      +  +S     H  G
Sbjct: 122  RAAPAFNQPLDRSRDVAEDKDFSITCSAS--GRPAPNVTW------VNKTSGSPVAHGTG 173

Query: 2433 YVSMTISHVRDEDEGVYMCRASN 2455
              ++++  ++    GVY C+A N
Sbjct: 174  SATLSLLKIQRHQAGVYQCQAIN 196


>SB_1246| Best HMM Match : Mito_carr (HMM E-Value=1.4013e-45)
          Length = 773

 Score = 37.9 bits (84), Expect = 0.20
 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 4224 YQRTETELEKTFEERQVLQRQGVIDHRPE-LKPKVIKEPET--EWQQSVKRKKNEEYYNK 4280
            Y+R    L KT E+ Q  Q++ +  H P   +P     P T  + QQ  ++++ ++   +
Sbjct: 363  YRRNRRHLRKTREQMQPPQKEDIEMHCPSPSRPAKPAMPTTHKQQQQQQQQQQQQQQQQQ 422

Query: 4281 LQELENEQVIKESRLRESTHQYAIPGDKVTSNTV 4314
             Q+ + +Q  ++ + ++   Q   P +K   NTV
Sbjct: 423  QQQQQQQQQQQQQQQQQQQQQEKQPSEKAPENTV 456


>SB_38167| Best HMM Match : Collagen (HMM E-Value=7e-12)
          Length = 299

 Score = 37.9 bits (84), Expect = 0.20
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 5/101 (4%)

Query: 3556 NPPEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFV 3615
            N P    +P +L ++ ++SA   C +I   D +  V W   G  L  G+R +     G V
Sbjct: 204  NAPRAEISPRELNVNASASAQLNCSIIS-GDPNAVVSWKRIGGDL-PGNRSRDDGRGGLV 261

Query: 3616 ILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGII 3656
            I +   V   DAG+Y C +    G +     + V G++ I+
Sbjct: 262  IRD---VRSSDAGMYECASAGGLGRSRDVALVSVNGKRQIM 299



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 5/72 (6%)

Query: 2387 NIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVSMTISHVRDEDE 2446
            N+    +A  +C +I  GDP   V W    K I       ++ D G   + I  VR  D 
Sbjct: 216  NVNASASAQLNCSIIS-GDPNAVVSW----KRIGGDLPGNRSRDDGRGGLVIRDVRSSDA 270

Query: 2447 GVYMCRASNLLG 2458
            G+Y C ++  LG
Sbjct: 271  GMYECASAGGLG 282



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 3311 DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECVATNKLGRDSTKA 3370
            DP+  V W   G  LP G+R R     G+VI D+      ++G YEC +   LGR    A
Sbjct: 233  DPNAVVSWKRIGGDLP-GNRSRDDGRGGLVIRDVR---SSDAGMYECASAGGLGRSRDVA 288

Query: 3371 NLKCTSKENLI 3381
             +    K  ++
Sbjct: 289  LVSVNGKRQIM 299



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 3449 DPNLKVEWYWNGKSLKAGSRFRTFCDFGFVILEISPTYPEDSGEYLCRAYNNYGEAVTTA 3508
            DPN  V W   G  L  G+R R     G VI ++  +   D+G Y C +    G +   A
Sbjct: 233  DPNAVVSWKRIGGDLP-GNRSRDDGRGGLVIRDVRSS---DAGMYECASAGGLGRSRDVA 288

Query: 3509 SMKVQGKRNII 3519
             + V GKR I+
Sbjct: 289  LVSVNGKRQIM 299



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 36/121 (29%), Positives = 51/121 (42%), Gaps = 15/121 (12%)

Query: 3800 PQGMSGEKIKELERGRISDAPKEEPIVSTPPKFITQIKSHTVEESEGVRFECRVEPKEDP 3859
            P+G  G +  + E GRI +AP+ E      P+ +       V  S   +  C +    DP
Sbjct: 186  PKGDVGPRGLKGEPGRIRNAPRAE----ISPREL------NVNASASAQLNCSI-ISGDP 234

Query: 3860 KLRIEWYRNGKLLPSGHRYRTVYDMGFVSLDILYVYAEDSGEYICRAVNDFGEDFTKATI 3919
               + W R G  LP G+R R   D G   L I  V + D+G Y C +    G     A +
Sbjct: 235  NAVVSWKRIGGDLP-GNRSR---DDGRGGLVIRDVRSSDAGMYECASAGGLGRSRDVALV 290

Query: 3920 S 3920
            S
Sbjct: 291  S 291



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 5/102 (4%)

Query: 1707 ITQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFG 1766
            I  AP   +  +++ V  + +A     +I  GDP   V W R G  +   NR     D G
Sbjct: 202  IRNAPRAEISPRELNVNASASAQLNCSIIS-GDPNAVVSWKRIGGDLPG-NR---SRDDG 256

Query: 1767 YVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASL 1808
               L ++ V   D+G Y C +   LG +   + + V  K  +
Sbjct: 257  RGGLVIRDVRSSDAGMYECASAGGLGRSRDVALVSVNGKRQI 298



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 2671 DPNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTA 2730
            DPN  + W + G  L  G R +     GLV   I  +R+ D+G+Y C +   LG +   A
Sbjct: 233  DPNAVVSWKRIGGDLP-GNRSRDDGRGGLV---IRDVRSSDAGMYECASAGGLGRSRDVA 288

Query: 2731 SIKIEDRHWLL 2741
             + +  +  ++
Sbjct: 289  LVSVNGKRQIM 299



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 19/83 (22%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLLI 4573
            P   ++ + +NV +    +L+  +    P  V    + K++  D+      +DG   L+I
Sbjct: 206  PRAEISPRELNVNASASAQLNCSIISGDPNAVV---SWKRIGGDLPGNRSRDDGRGGLVI 262

Query: 4574 LEAYPQDSGKYECVAINSAGEAR 4596
             +    D+G YEC +    G +R
Sbjct: 263  RDVRSSDAGMYECASAGGLGRSR 285



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 5/83 (6%)

Query: 1861 SAHYECRIEPYPDPNMRVEWYFNGKVLQSGHRYRTSNDFGFAALDILTVYGEDSGEYTCK 1920
            SA   C I    DPN  V W   G  L  G+R   S D G   L I  V   D+G Y C 
Sbjct: 222  SAQLNCSIIS-GDPNAVVSWKRIGGDLP-GNR---SRDDGRGGLVIRDVRSSDAGMYECA 276

Query: 1921 AINNLGQAVSSIRLNVQSKESII 1943
            +   LG++     ++V  K  I+
Sbjct: 277  SAGGLGRSRDVALVSVNGKRQIM 299



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 2120 NLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGYVALDILYTYAEDS 2179
            N+     A   C +    DP+  + W   G  +  G+R R     G V  D+    + D+
Sbjct: 216  NVNASASAQLNCSIIS-GDPNAVVSWKRIGGDL-PGNRSRDDGRGGLVIRDVR---SSDA 270

Query: 2180 GTYMCKATNKLGEAVNTCTLKVAGHRNII 2208
            G Y C +   LG + +   + V G R I+
Sbjct: 271  GMYECASAGGLGRSRDVALVSVNGKRQIM 299


>SB_47033| Best HMM Match : WAP (HMM E-Value=1.8e-38)
          Length = 667

 Score = 37.5 bits (83), Expect = 0.26
 Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 2/95 (2%)

Query: 268 IAQKPRNSKLQEGADAQFQVQLSGNPRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRN 327
           + +K     L+ G     +V + G P P+  W K+ Q L        +       L ++N
Sbjct: 391 VEKKKSFQYLRPGEVGLIEVSIRGYPLPKSKWIKDNQPLNYRTGRYAVGKMGF--LGIKN 448

Query: 328 TQKSDSGHYTLLAENPNGCIVTSGYLAVESPTESY 362
            Q+SD G Y+L+ +N     V    +    PT +Y
Sbjct: 449 VQRSDKGMYSLVLDNALEADVEVQVVQESCPTPTY 483



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 392 PQFVKVCQDRD-VTEGKMTRFDCRVTGRPYPEVTWFI-NDRQIRDDYNHKILVNESGNH- 448
           PQ       RD +  G+  R  C V  +P+  V WF  N ++I    + ++ V + G + 
Sbjct: 578 PQVKAFSPGRDRLNTGEAVRRVCLVYRQPF--VGWFASNGQKIMSSRDERMFVEDHGIYK 635

Query: 449 ALMITNVTLSDSGVVTC 465
            L+I NVT+ D+G   C
Sbjct: 636 VLVIRNVTVEDAGTYEC 652


>SB_57573| Best HMM Match : 7tm_2 (HMM E-Value=3.7e-40)
          Length = 956

 Score = 37.5 bits (83), Expect = 0.26
 Identities = 32/143 (22%), Positives = 62/143 (43%), Gaps = 7/143 (4%)

Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRL-RESTHQYAIPGDKVTSNTVAKSMAQRYED 4324
            ++ +KR K+++YY K +  +  QVI+  ++ RE T   + P  ++       S  +R E 
Sbjct: 701  KKEIKRAKDKDYYEKNRNKKIAQVIERRKVCREETIGKSRPRTEIRK---VASTKRRKEQ 757

Query: 4325 NLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITRK 4381
                 EE+  +R   ++K  ++ R          G+E  + +   +  K     K +T K
Sbjct: 758  RATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKILQNTGERFKNRTSKKRVTDK 817

Query: 4382 ITSTETTEIEHKAQTQERVVEGP 4404
            +        E KA+  E ++  P
Sbjct: 818  VKDKLPQTPEKKAEVLETLINSP 840


>SB_50620| Best HMM Match : Lectin_C (HMM E-Value=2.1e-14)
          Length = 620

 Score = 37.5 bits (83), Expect = 0.26
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 4/54 (7%)

Query: 4110 PPVFVSLPDA---VTVEEGEWARFCCRVTGHPKPRVMWLLNGNTIVNGSRYKLT 4160
            PP  VS P+    +TV  G      C  TG P+P + WL NG  + +G+  K+T
Sbjct: 136  PPDIVS-PNGLVYITVAYGTMVNQSCVTTGLPRPEIQWLANGKQLRDGNDVKVT 188



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKI 440
           V  G M    C  TG P PE+ W  N +Q+RD  + K+
Sbjct: 150 VAYGTMVNQSCVTTGLPRPEIQWLANGKQLRDGNDVKV 187



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 4523 VNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQP--DIRNKILEEDGTYTLLILEAYPQD 4580
            + V  G +V      TG    ++ WL NGK+++   D++  +L      TL +L+     
Sbjct: 148  ITVAYGTMVNQSCVTTGLPRPEIQWLANGKQLRDGNDVKVTLLPYMANVTLKVLK----- 202

Query: 4581 SGKYECVAINSAGEARCDAECVV 4603
            + + +C +IN  G A+     +V
Sbjct: 203  NTELQCQSINRGGVAKASVMYIV 225



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 2/45 (4%)

Query: 4622 PPEIIEP--LKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK 4664
            PP+I+ P  L    VA G  +  SC   G P P +QW    K ++
Sbjct: 136  PPDIVSPNGLVYITVAYGTMVNQSCVTTGLPRPEIQWLANGKQLR 180


>SB_44087| Best HMM Match : I-set (HMM E-Value=1.5e-05)
          Length = 267

 Score = 37.5 bits (83), Expect = 0.26
 Identities = 24/83 (28%), Positives = 31/83 (37%), Gaps = 9/83 (10%)

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
            P    I   G ++   C + GKP P + W         SK       +    +RI     
Sbjct: 188  PTNHTIAKIGSSVSLECDVKGKPPPNITW---------SKLGDNQWRSKGSVIRIFNFTV 238

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKL 4710
            ED G Y+C AYN  G    A  L
Sbjct: 239  EDRGIYECSAYNGIGPNVTAVSL 261


>SB_12530| Best HMM Match : I-set (HMM E-Value=3e-05)
          Length = 127

 Score = 37.5 bits (83), Expect = 0.26
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 8/88 (9%)

Query: 4625 IIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISE 4684
            II   +D+   EG  +   C + G P+P+V W K    +      Q+  T+ +Y  R+S 
Sbjct: 5    IINASRDQNAIEGDPLTPICDVDGYPVPSVVWSKTPDSV------QLPATSPQY--RVSA 56

Query: 4685 AFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                D   Y C A N  G  + + K+ V
Sbjct: 57   VRSADARIYTCFASNEMGNASASMKVVV 84


>SB_11355| Best HMM Match : I-set (HMM E-Value=1.5e-05)
          Length = 288

 Score = 37.5 bits (83), Expect = 0.26
 Identities = 24/83 (28%), Positives = 31/83 (37%), Gaps = 9/83 (10%)

Query: 4628 PLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFP 4687
            P    I   G ++   C + GKP P + W         SK       +    +RI     
Sbjct: 144  PTNHTIAKIGSSVSLECDVKGKPPPNITW---------SKLGDNQWRSKGSVIRIFNFTV 194

Query: 4688 EDEGDYKCVAYNSAGRVTVAAKL 4710
            ED G Y+C AYN  G    A  L
Sbjct: 195  EDRGIYECSAYNGIGPNVTAVSL 217



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 12/121 (9%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            + DV     + P  ++     T    G S   EC ++  P PN  + W   G      ++
Sbjct: 127  QNDVSFRSFRKPNLLSYPTNHTIAKIGSSVSLECDVKGKPPPN--ITWSKLGD-----NQ 179

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQAVSSIRLNVQSKESIIRDSQHESAL 1952
            +R+      + + I     ED G Y C A N +G  V+++ L VQ      R ++ E  +
Sbjct: 180  WRSKG----SVIRIFNFTVEDRGIYECSAYNGIGPNVTAVSL-VQYTGCTSRCAKKEVGV 234

Query: 1953 E 1953
            E
Sbjct: 235  E 235


>SB_7591| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 3261

 Score = 37.5 bits (83), Expect = 0.26
 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 6/74 (8%)

Query: 505  GEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCT 564
            G+P +L     G+P   I W KD  P +P+     H     +TL I   +A D   Y+C 
Sbjct: 3073 GKPGLLTCLFDGSPRS-IVWSKDDSPSLPS-----HMTANGNTLTISSVQAQDQGSYECM 3126

Query: 565  AQNVAGSTATRARL 578
            A +   S A +  L
Sbjct: 3127 ATDEFNSVAAKVSL 3140



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 7/87 (8%)

Query: 4643 SCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAG 4702
            +C   G P   V W K D    PS       TA+  TL IS    +D+G Y+C+A +   
Sbjct: 3079 TCLFDGSPRSIV-WSKDDSPSLPSHM-----TANGNTLTISSVQAQDQGSYECMATDEFN 3132

Query: 4703 RVTVAAKLKVTQ-PDQADNLPALTPLR 4728
             V     L++   P     LPA   LR
Sbjct: 3133 SVAAKVSLRILGIPVLGRGLPARCLLR 3159


>SB_48288| Best HMM Match : ig (HMM E-Value=6.9e-08)
          Length = 234

 Score = 37.1 bits (82), Expect = 0.35
 Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 5/62 (8%)

Query: 940  TLRVEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANL 999
            T  + W K G      S ITT      +   I SV   DAG YTC A N IG  + + ++
Sbjct: 4    TPNITWTKQGVSAALRSNITT-----EIIHQIASVQKSDAGRYTCAANNEIGAVSRTLSV 58

Query: 1000 TI 1001
            T+
Sbjct: 59   TV 60



 Score = 37.1 bits (82), Expect = 0.35
 Identities = 16/38 (42%), Positives = 21/38 (55%)

Query: 4514 PSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNG 4551
            PS T    N+ VT G LV L    +G+ P++V W K G
Sbjct: 150  PSITFITANMTVTEGSLVNLQCNTSGSLPLNVSWSKVG 187



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%)

Query: 2672 PNLKIEWFKNGVTLTTGARLKSTFDFGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTAS 2731
            P   I W K GV+    A L+S     ++   I S++  D+G YTC A N +G    T S
Sbjct: 3    PTPNITWTKQGVS----AALRSNITTEIIH-QIASVQKSDAGRYTCAANNEIGAVSRTLS 57

Query: 2732 IKI 2734
            + +
Sbjct: 58   VTV 60



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 5/55 (9%)

Query: 293 PRPRVTWFKNGQRLINSNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCI 347
           P P +TW K G   +++     ITT      ++ + QKSD+G YT  A N  G +
Sbjct: 3   PTPNITWTKQG---VSAALRSNITTE--IIHQIASVQKSDAGRYTCAANNEIGAV 52



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 5/66 (7%)

Query: 3725 PTMRIDWFHNGRPFATGSRVHTLNDFGFIALDIDYIYARDAGEYTCRATNKWGSATTTAK 3784
            PT  I W   G   A  S + T      I   I  +   DAG YTC A N+ G+ + T  
Sbjct: 3    PTPNITWTKQGVSAALRSNITTE-----IIHQIASVQKSDAGRYTCAANNEIGAVSRTLS 57

Query: 3785 ITCSAK 3790
            +T   K
Sbjct: 58   VTVHYK 63



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 6/79 (7%)

Query: 1740 PKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSST 1799
            P   + W + GV     + +TT      +   +  V   D+G YTC A NE+G    + +
Sbjct: 3    PTPNITWTKQGVSAALRSNITTE-----IIHQIASVQKSDAGRYTCAANNEIGAVSRTLS 57

Query: 1800 LFVQSK-ASLQLESQHESA 1817
            + V  K  + QL +   SA
Sbjct: 58   VTVHYKPINTQLATTKTSA 76



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 5/63 (7%)

Query: 800 PTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAISTAS 859
           PT  + W K G      S IT+      +   I  ++  DAG YT  A N++G    T S
Sbjct: 3   PTPNITWTKQGVSAALRSNITT-----EIIHQIASVQKSDAGRYTCAANNEIGAVSRTLS 57

Query: 860 IRV 862
           + V
Sbjct: 58  VTV 60


>SB_50351| Best HMM Match : I-set (HMM E-Value=0.00016)
          Length = 419

 Score = 37.1 bits (82), Expect = 0.35
 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 3/72 (4%)

Query: 1603 PVSDATLKVEWYHNNKPLKSGSRFTETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAV 1662
            P +   L   WYHN  P+    R + T+N   +  D+M     D+G Y   A N+ G++ 
Sbjct: 14   PRARGALTYTWYHNAVPVSPDHRVSVTSNGSLLIKDVMR---PDNGIYQVFAENSFGKSS 70

Query: 1663 TSGIAIVHSKKS 1674
               + ++ S+K+
Sbjct: 71   AEPVYLLVSEKT 82


>SB_24929| Best HMM Match : ig (HMM E-Value=8.2e-06)
          Length = 186

 Score = 37.1 bits (82), Expect = 0.35
 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 10/107 (9%)

Query: 1833 REDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYFNGKVLQSGHR 1892
            +E + V   +AP     LNG   ++E       C     P PN  V W    K   S   
Sbjct: 87   KEILRVVSTEAPALNPPLNGSHDVAEDTDFSITCSASGRPAPN--VTWV--NKTSGSPVA 142

Query: 1893 YRTSNDFGFAALDILTVYGEDSGEYTCKAINNLGQ--AVSSIRLNVQ 1937
            + T    G A L +L +    +G Y C+AIN++ +   +  + +NVQ
Sbjct: 143  HGT----GSATLSLLKIQRHQAGVYQCQAINDVRREAIIQDVTINVQ 185


>SB_21954| Best HMM Match : V-set (HMM E-Value=0.011)
          Length = 291

 Score = 37.1 bits (82), Expect = 0.35
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 11/91 (12%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP  T+  Q+ N+T      +  +V G +P+ V WLK   +V    R   + E     L+
Sbjct: 157  PPLITIPIQSPNLTV-----IGIEVKGLRPVQVRWLKGDMEVDGQQRRFYINE--AMDLV 209

Query: 4573 ILEAYP-QDSGKYECVAINSAGEARCDAECV 4602
            +   Y   DSG YE +A N      C   C+
Sbjct: 210  LSPPYSLSDSGSYEVMACNLVA---CVVRCI 237



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 19/154 (12%)

Query: 4553 KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSAGEARC--DAECVVSLPATKD 4610
            +V PD + +I +  G + +L L   P DSG Y C  ++  G  +    AE VV   A  D
Sbjct: 87   EVLPD-KTRIAKIGGVFHILDLS--PLDSGTYSCKGLDEKGVQKTIEIAELVVKRHAA-D 142

Query: 4611 KPKPQTK---AANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIK-PS 4666
            K  P +K       PP I  P++              ++ G     V+W KGD  +    
Sbjct: 143  KIPPGSKPYIKFKTPPLITIPIQSP-----NLTVIGIEVKGLRPVQVRWLKGDMEVDGQQ 197

Query: 4667 KYFQMSRTADEYTLRISEAFP-EDEGDYKCVAYN 4699
            + F ++   D   L +S  +   D G Y+ +A N
Sbjct: 198  RRFYINEAMD---LVLSPPYSLSDSGSYEVMACN 228


>SB_11731| Best HMM Match : ig (HMM E-Value=1e-06)
          Length = 220

 Score = 37.1 bits (82), Expect = 0.35
 Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 31/177 (17%)

Query: 406 GKMTRFDCRVTGRPYPEVTW-FINDRQIRDDYN---HKILVNESGNHALMITNVTLSDSG 461
           G      C   G P   +   ++++  IR + N   H IL++  G H  ++T V ++D+G
Sbjct: 20  GAAISLTCSAVGEPQLIIYHLYMDNLLIRKNINGMFHNILLDSVGIH--LLTCVPINDAG 77

Query: 462 VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPR 521
           V      N+S        +NV EK   ++       +T+N  EG  VV    A+G  + +
Sbjct: 78  V----GENRS------VSMNVTEKLPTIS--ITPLRATVN--EGSVVVFTCLAIGFQSFK 123

Query: 522 ITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNVAGSTATRARL 578
             W+KDGV             G  S+L +      D   Y C   +  G+T   A L
Sbjct: 124 NFWKKDGV-----------FKGDGSSLTLSSVGTDDRGNYTCNVTSTCGTTMKTASL 169



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 13/34 (38%), Positives = 22/34 (64%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +L+++S+  DD G YTC  T+  G  + TAS+ +
Sbjct: 138  SLTLSSVGTDDRGNYTCNVTSTCGTTMKTASLDV 171



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 13/39 (33%), Positives = 22/39 (56%)

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
            +LT+ SV   D G+YTC   +  G    +A+L ++ K +
Sbjct: 138  SLTLSSVGTDDRGNYTCNVTSTCGTTMKTASLDVIYKPE 176


>SB_43527| Best HMM Match : Trypsin (HMM E-Value=0)
          Length = 366

 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 296 RVTWFKNGQRLIN-SNKHEIITTHNHTTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLA 354
           RV WFKNG  + + S  H    +  H    V +   SD G YT  A  P   I  S YL+
Sbjct: 6   RVKWFKNGIEIPSLSEGHYFTASEGHLVFLVAHY--SDRGMYTCKATTPAATIEASAYLS 63

Query: 355 V 355
           V
Sbjct: 64  V 64



 Score = 36.7 bits (81), Expect = 0.46
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 4752 IQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQVETSAKLVVK 4811
            ++W + G  IP   +          ++ +   Y  D G +TC+ATT A  +E SA L V+
Sbjct: 7    VKWFKNGIEIPSLSEGHYFTASEGHLVFLVAHYS-DRGMYTCKATTPAATIEASAYLSVR 65



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 3590 RVEWFHNGK--PLLTGSRVKTINDFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKL 3647
            RV+WF NG   P L+     T ++   V L     +  D G+YTCKAT        S  L
Sbjct: 6    RVKWFKNGIEIPSLSEGHYFTASEGHLVFLV---AHYSDRGMYTCKATTPAATIEASAYL 62

Query: 3648 QVKG 3651
             V+G
Sbjct: 63   SVRG 66



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 5/63 (7%)

Query: 1477 KVEWFKNGQPVTIGHRFRPIHDFGYVALDIIDLIAE--DSGIYTCRAVNLVGTDEVSCRL 1534
            +V+WFKNG  +         H F      ++ L+A   D G+YTC+A     T E S  L
Sbjct: 6    RVKWFKNGIEIP---SLSEGHYFTASEGHLVFLVAHYSDRGMYTCKATTPAATIEASAYL 62

Query: 1535 TCR 1537
            + R
Sbjct: 63   SVR 65



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 1/60 (1%)

Query: 669 KIEWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
           +++W KNG  I + S     F      L  L  +  D G YTC+A +     E  A L V
Sbjct: 6   RVKWFKNGIEIPSLSE-GHYFTASEGHLVFLVAHYSDRGMYTCKATTPAATIEASAYLSV 64


>SB_30644| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1887

 Score = 36.7 bits (81), Expect = 0.46
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 2/66 (3%)

Query: 798 SDPTMRVEWYKDGRPITASSRITSIFNFGYVSLNIMHLRAEDAGSYTVRAVNKLGEAIST 857
           S P  +  WYK GRP+   S   S+   G  SL I  +R+ D G YT++A       +  
Sbjct: 16  SYPLSKFVWYKRGRPLDMDSGRFSVSPSG--SLGIRRVRSVDVGIYTLKAQGGDEGVVQD 73

Query: 858 ASIRVA 863
             I VA
Sbjct: 74  TGISVA 79


>SB_29861| Best HMM Match : RRM_1 (HMM E-Value=1.10002e-42)
          Length = 1531

 Score = 36.7 bits (81), Expect = 0.46
 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 15/164 (9%)

Query: 4248 DHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTH-----QY 4302
            DH+P       ++PE    ++  R++     NK  EL  E+  K+ + ++S       + 
Sbjct: 580  DHKPSQHQDYPEKPEHSIPKAENRERMPSVENK-SELAEERKGKKKKEKKSKRPLQPGEG 638

Query: 4303 AIPGDKVTSNTVAKSMAQRYEDNL----DQTEEVTEQRVQKKVTQKPRIPDPSESTVHGK 4358
               G       VAK   +  E+      D+T E+TE   +      P  P+PS  T   K
Sbjct: 639  GSRGSDTEEEVVAKRRKKVKEEERVTQPDKTSELTESTKRPAADAPPPTPEPSLPTEKKK 698

Query: 4359 EVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERVVE 4402
                 K+K+ +KE   +K+  R  T  E  E   K     RV E
Sbjct: 699  -----KEKREKKERKREKKTRRARTPVEEPENFEKDVPLPRVHE 737


>SB_17408| Best HMM Match : I-set (HMM E-Value=7.4e-06)
          Length = 136

 Score = 36.7 bits (81), Expect = 0.46
 Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 2/75 (2%)

Query: 4735 GQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCR 4794
            G    F   +T   KPT+QW+  G    E   F   +E       I N    D G +TCR
Sbjct: 19   GYNTSFTCIVTGFPKPTVQWINPGG--REVDTFDPRYEIIGDTFYIYNIESNDKGNWTCR 76

Query: 4795 ATTAAGQVETSAKLV 4809
             T     +E  A ++
Sbjct: 77   VTGGDVTIEAVATII 91



 Score = 36.3 bits (80), Expect = 0.61
 Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 16/97 (16%)

Query: 265 PPKIAQKPRNSK--LQEGADAQFQVQLSGNPRPRVTWFKNGQRLINS--NKHEIITTHNH 320
           PP+I Q+P   K  +  G +  F   ++G P+P V W   G R +++   ++EII     
Sbjct: 2   PPEIIQQPVPIKRYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEII----G 57

Query: 321 TTLRVRNTQKSDSGHYTLLAENPNGCIVTSGYLAVES 357
            T  + N + +D G++T        C VT G + +E+
Sbjct: 58  DTFYIYNIESNDKGNWT--------CRVTGGDVTIEA 86



 Score = 35.9 bits (79), Expect = 0.80
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 4110 PPVFVSLPDAVT--VEEGEWARFCCRVTGHPKPRVMWLLNGNTIVN--GSRYKLTYDGMY 4165
            PP  +  P  +   V  G    F C VTG PKP V W+  G   V+    RY++  D  Y
Sbjct: 2    PPEIIQQPVPIKRYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRYEIIGDTFY 61

Query: 4166 HFDI 4169
             ++I
Sbjct: 62   IYNI 65



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 4/38 (10%)

Query: 4622 PPEIIE---PLKDKIVAEGQAIEFSCKIVGKPLPTVQW 4656
            PPEII+   P+K + V  G    F+C + G P PTVQW
Sbjct: 2    PPEIIQQPVPIK-RYVTVGYNTSFTCIVTGFPKPTVQW 38



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 5/84 (5%)

Query: 401 RDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDS 460
           R VT G  T F C VTG P P V W     +  D ++ +    E       I N+  +D 
Sbjct: 14  RYVTVGYNTSFTCIVTGFPKPTVQWINPGGREVDTFDPRY---EIIGDTFYIYNIESNDK 70

Query: 461 GVVTCVARNKSGETAFQCRLNVIE 484
           G  TC  R   G+   +    +I+
Sbjct: 71  GNWTC--RVTGGDVTIEAVATIID 92


>SB_53466| Best HMM Match : SCP (HMM E-Value=2.4e-27)
          Length = 5087

 Score = 36.7 bits (81), Expect = 0.46
 Identities = 33/162 (20%), Positives = 69/162 (42%), Gaps = 6/162 (3%)

Query: 4219 DETTQ-YQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEY 4277
            +ET + ++R   EL    +E + L++Q  +D++ +    +  E E   Q   ++ K +E+
Sbjct: 4504 EETKESFERKSEELSAVTKECEALKKQ--LDNKSDQLSSLHDERELSLQNLQEQLKQKEF 4561

Query: 4278 Y--NKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQ 4335
               +  +E++  +   E    +   Q     D++    +     QR ED + Q  E  E 
Sbjct: 4562 ELSSLKEEVDTTKQFAEQAANQMNEQQQEYEDQLRKMEMLYGELQRSEDTIHQLVEENEH 4621

Query: 4336 RVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKE 4377
                  + +  + +  E++   +EVH    +   KE   D+E
Sbjct: 4622 LRTVLDSHEDTVSEEGEASTSSEEVHY-HDESPAKEEASDEE 4662


>SB_48507| Best HMM Match : TolA (HMM E-Value=1)
          Length = 649

 Score = 36.7 bits (81), Expect = 0.46
 Identities = 53/236 (22%), Positives = 96/236 (40%), Gaps = 18/236 (7%)

Query: 4198 KVIPRHDDYRGVLKNAPRPWYDETTQYQRTE------TELEKTFEERQVLQRQG------ 4245
            K++   +  RG     P+    E T+++ TE      TE     +E++V++ +G      
Sbjct: 318  KIVDVEEGNRGGSVLEPKTKPTEATRHKPTEGVQPQPTEQGMVEDEKKVVEVEGGKGGGP 377

Query: 4246 VIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQE--LENEQVIKESRLRESTHQYA 4303
            + DH+ E   +   +P TE +  V R   ++     +   +E+E+ + +           
Sbjct: 378  LPDHKTEPTDRTRPKP-TEPEAGVARDDIDDMKAAKRSGIVEDEKKVVDVEKGNRGGSLL 436

Query: 4304 IPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVA 4363
             P  + T  T  K     +    +Q     E     KV    +I D  E     KE+ V 
Sbjct: 437  EPKTEPTEATRPKHSEGVHPQPTEQGVAEDENE-DLKVAVSGKIVDVEEGNEGNKELVVP 495

Query: 4364 KQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERV-VEGPVKPSKPPIFTKKMQ 4418
            K + T++ V    E T  I +  TT  EH+ +T+E+  ++    P + P  T  +Q
Sbjct: 496  KSR-TEELVYTTHEPTAPIETVTTTIKEHRLRTEEKTHLKSTTSPGQEPSTTSSVQ 550


>SB_11578| Best HMM Match : ig (HMM E-Value=3.3e-23)
          Length = 259

 Score = 36.7 bits (81), Expect = 0.46
 Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 19/138 (13%)

Query: 437 NHKILVNESGNHALMITNVTLSDSG--VVTCVARNKSGETAFQCRLNVIEKEQVVAPKFV 494
           N  +  N +G    ++ N+ L+ SG  V TCV  N+ GE     +  ++   +V+    V
Sbjct: 129 NQAVKTNTNG----VLNNIKLNTSGEHVFTCVPTNEIGEGLN--KTVIVNASEVLPVVSV 182

Query: 495 ERFSTLNVREGEPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAK 554
           +      + +G  V L     G    +I+W KD + I           G   TL I +  
Sbjct: 183 DIPPNGRMVKGSSVTLTCNGTGPVPLQISWYKDNIFI-----------GSGKTLTISKVT 231

Query: 555 ASDAAWYQCTAQNVAGST 572
             D   Y C   +  G+T
Sbjct: 232 VQDEGNYTCNVSSSCGTT 249



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 1/49 (2%)

Query: 4110 PPVFVSLPDAVTVEEGEWARFCCRVTGHPKPRVMWLL-NGNTIVNGSRY 4157
            P   V  P + TV E +     C   G P P   W+   G+T+V+G  Y
Sbjct: 3    PSSVVISPPSPTVTERDQVNLTCSADGTPPPTFTWISPQGHTVVHGPSY 51


>SB_3034| Best HMM Match : I-set (HMM E-Value=5e-09)
          Length = 84

 Score = 36.7 bits (81), Expect = 0.46
 Identities = 15/29 (51%), Positives = 20/29 (68%)

Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            D +   +AG YTC ATN+ GS TTT ++T
Sbjct: 53   DSVTRSEAGTYTCTATNEMGSDTTTVQVT 81



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 14/29 (48%), Positives = 19/29 (65%)

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            SVT  +AG YTC A N +G  TT+  +T+
Sbjct: 54   SVTRSEAGTYTCTATNEMGSDTTTVQVTV 82


>SB_56618| Best HMM Match : DUF1213 (HMM E-Value=0.022)
          Length = 1421

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 20/112 (17%), Positives = 56/112 (50%), Gaps = 2/112 (1%)

Query: 4262 ETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRE--STHQYAIPGDKVTSNTVAKSMA 4319
            E + ++  K+K+ EE   K +E+E  ++ +E R +E   + ++    D++      +   
Sbjct: 1182 EVQKKREEKKKREEEMREKEKEMEQNKIDQEKRKQELMESRRFQEEQDRLEEERRLEEER 1241

Query: 4320 QRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKE 4371
             R  +  D+   + E+++++   +  R+ +  E     +++  A++++ Q+E
Sbjct: 1242 LRQLEEEDEQRRLEEEQIREAEEELRRLQEEREYREQMRKIAEARERKLQEE 1293


>SB_55200| Best HMM Match : E-MAP-115 (HMM E-Value=0.85)
          Length = 929

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 9/144 (6%)

Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK--SMAQRYE 4323
            ++ +KR K+++YY K +  +  QVI+  + R    +    G   T   + K  S  +R E
Sbjct: 15   KKEIKRAKDKDYYEKNRNKKIAQVIERRKARREETK----GKSRTRTEIKKAASKKRRKE 70

Query: 4324 DNLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITR 4380
                  EE+  +R   ++K  ++ R          G+E  + +   +  K     K +T 
Sbjct: 71   QRATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKILQNTGERFKNRTSKKRVTD 130

Query: 4381 KITSTETTEIEHKAQTQERVVEGP 4404
            K+        E KA+  E ++  P
Sbjct: 131  KVKDKLPQTPEKKAEVLETLINSP 154


>SB_49614| Best HMM Match : E-MAP-115 (HMM E-Value=0.85)
          Length = 838

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 9/144 (6%)

Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK--SMAQRYE 4323
            ++ +KR K+++YY K +  +  QVI+  + R    +    G   T   + K  S  +R E
Sbjct: 15   KKEIKRAKDKDYYEKNRNKKIAQVIERRKARREETK----GKSRTRTEIKKAASKKRRKE 70

Query: 4324 DNLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITR 4380
                  EE+  +R   ++K  ++ R          G+E  + +   +  K     K +T 
Sbjct: 71   QRATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKILQNTGERFKNRTSKKRVTD 130

Query: 4381 KITSTETTEIEHKAQTQERVVEGP 4404
            K+        E KA+  E ++  P
Sbjct: 131  KVKDKLPQTPEKKAEVLETLINSP 154


>SB_40579| Best HMM Match : E-MAP-115 (HMM E-Value=0.85)
          Length = 929

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 9/144 (6%)

Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK--SMAQRYE 4323
            ++ +KR K+++YY K +  +  QVI+  + R    +    G   T   + K  S  +R E
Sbjct: 15   KKEIKRAKDKDYYEKNRNKKIAQVIERRKARREETK----GKSRTRTEIKKAASKKRRKE 70

Query: 4324 DNLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITR 4380
                  EE+  +R   ++K  ++ R          G+E  + +   +  K     K +T 
Sbjct: 71   QRATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKILQNTGERFKNRTSKKRVTD 130

Query: 4381 KITSTETTEIEHKAQTQERVVEGP 4404
            K+        E KA+  E ++  P
Sbjct: 131  KVKDKLPQTPEKKAEVLETLINSP 154


>SB_33143| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 234

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 4328 QTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTET 4387
            +TE +TE +   + T+  +  + S+      E     +  T+K    +K+ + KI + + 
Sbjct: 53   KTETITETKRSDEETKSDQETNRSDEVTKRSEPETTDR--TEKVEESEKQNSDKINNNDE 110

Query: 4388 TEIEHKAQTQ-ERVVEGPVKPSKPPIFTKKMQP 4419
            T+IE  A+   E  ++GP  P+ P   T    P
Sbjct: 111  TQIESNAEAPIEAKLDGPTSPTSPTTPTSPRTP 143


>SB_54309| Best HMM Match : SH2 (HMM E-Value=5.1e-17)
          Length = 1249

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 39/186 (20%), Positives = 82/186 (44%), Gaps = 10/186 (5%)

Query: 4220 ETTQYQRTETELEKTFEERQVLQR--QGVIDHRPELKPKVIKEPETEWQQ-SVKRKKNEE 4276
            E  + QR E E ++  +ERQ ++   Q + D R   +   I   E E ++   +R+K  +
Sbjct: 432  EEDERQRAEDERQRAEDERQRVKHEMQRLKDERRRAEEDEIARQEEELRRLQEQREKELK 491

Query: 4277 YYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQR 4336
             Y +LQ  E E+  KE+  RE   Q     D++      +  A+R     +Q E++    
Sbjct: 492  RYKELQMAEEEKRRKETEERE--RQAREEEDRIRRE---REEAERLRREKEQREQLVPHS 546

Query: 4337 VQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQT 4396
               +   KP   +  E+ +  +++   +++  + +   + +  +++        E KAQ 
Sbjct: 547  DALECAIKPL--NLLEARIKAQKLEEEQRELERLQAEAELKRKQELERLREKRKEEKAQR 604

Query: 4397 QERVVE 4402
            +  ++E
Sbjct: 605  ERELIE 610



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 34/175 (19%), Positives = 78/175 (44%), Gaps = 13/175 (7%)

Query: 4228 ETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENE 4287
            E + E   +E ++++ +   +   EL  + +   E E Q+  +R+  EE        E +
Sbjct: 141  EVDAEAKQKEAELIEDKLAEEKARELAHQEMLRKEQEQQEEEERRIREEE-------ERQ 193

Query: 4288 QVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTE--EVTEQRVQKKVTQKP 4345
            + +KE R+R+   +  +   +       K   +R E    + E  E+ ++R +++  Q+ 
Sbjct: 194  KALKEERMRKLQEEARLAAQRALEEK-RKLEEERKEQERKEKELAELEKKRQEERRRQEE 252

Query: 4346 RIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQERV 4400
            +     E+    +E   A++K   +E +   ++  K    E  ++E + + +ERV
Sbjct: 253  KRRAEEEAKRKAEEEKAAREKAEMEEKLRRLKLQEK---EEKRKLEAEKKEKERV 304


>SB_26345| Best HMM Match : DUF1531 (HMM E-Value=2.4)
          Length = 169

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 6/130 (4%)

Query: 4270 KRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQT 4329
            + K NEE    L E E ++  K+   ++ T +  +P    T    A+   ++ ++  +  
Sbjct: 44   QEKSNEE----LPESEKKKKKKKKDKKKKTEEETVPETVQTETPSARKKKKKEKEQEETM 99

Query: 4330 EEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKI-TSTETT 4388
            EE   +       +K R  +  E      E    K+K+ + E   D EI   I TS +  
Sbjct: 100  EEQQTEATSSAKKKKKRKVEDVEDVEEKVEAETPKKKKKKSETTED-EIEESINTSEKKK 158

Query: 4389 EIEHKAQTQE 4398
            + + K QT+E
Sbjct: 159  KKKKKKQTEE 168


>SB_23339| Best HMM Match : I-set (HMM E-Value=1.3e-07)
          Length = 423

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 11/83 (13%)

Query: 2376 PVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKVEWFRNEKLIEDSSRITKTHDFGYVS 2435
            PV   PL ++D   E +T    C+ I  GD  + + W  N+ L+++ S  T        +
Sbjct: 122  PVIFSPLPDVD-AYENKTITLQCQAI--GDAVISIAWLHNDTLVQNRSVNT--------A 170

Query: 2436 MTISHVRDEDEGVYMCRASNLLG 2458
            + IS +     G + C ASN LG
Sbjct: 171  LVISKIPLNMSGSWRCVASNHLG 193



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 9/73 (12%)

Query: 400 DRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSD 459
           D D  E K     C+  G     + W  ND  ++         N S N AL+I+ + L+ 
Sbjct: 130 DVDAYENKTITLQCQAIGDAVISIAWLHNDTLVQ---------NRSVNTALVISKIPLNM 180

Query: 460 SGVVTCVARNKSG 472
           SG   CVA N  G
Sbjct: 181 SGSWRCVASNHLG 193



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 8/80 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I  PL D    E + I   C+ +G  + ++ W   D L++       +R+ +   L I
Sbjct: 122  PVIFSPLPDVDAYENKTITLQCQAIGDAVISIAWLHNDTLVQ-------NRSVNT-ALVI 173

Query: 4683 SEAFPEDEGDYKCVAYNSAG 4702
            S+      G ++CVA N  G
Sbjct: 174  SKIPLNMSGSWRCVASNHLG 193



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 11/99 (11%)

Query: 1177 PVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRSVTVGSRFKTYYDFGFVA 1236
            PV   PL +     E K I L+C  + +GD  + + W HN   V   S   T      + 
Sbjct: 122  PVIFSPLPDVDAY-ENKTITLQC--QAIGDAVISIAWLHNDTLVQNRS-VNTALVISKIP 177

Query: 1237 LDIIHATSADTGEYTVRAVNHLGSAHTSAIVRVIERSDI 1275
            L++       +G +   A NHLGS + +  V V + SD+
Sbjct: 178  LNM-------SGSWRCVASNHLGSQNKTFFVGVKKPSDL 209


>SB_18255| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1457

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 41/179 (22%), Positives = 81/179 (45%), Gaps = 21/179 (11%)

Query: 4220 ETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYN 4279
            ET +Y   + + EK  E+R    R+       ELK K + E  +     + +  +E+   
Sbjct: 98   ETERYSAIQ-QAEKALEDRNFAIRES------ELKSKQLMEKYS----LLSKTASEDANA 146

Query: 4280 KLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQK 4339
            K +EL+ +  + E  L +   + A   +++  + +A + AQR   +L++    TE++  +
Sbjct: 147  KCRELKEKLSLAEKSLSDRDAELAQLRNEINQSVMAFNNAQRESIDLEKQLAATERKHNE 206

Query: 4340 KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQE 4398
             +++     D   + +  +E H+A+Q       V   E   +I+S E  E E K +  E
Sbjct: 207  LISEY----DSLNAKLQAREQHIAEQ------AVSIVEYKHRISSLEQNESECKERLFE 255


>SB_15709| Best HMM Match : CAP_GLY (HMM E-Value=0)
          Length = 729

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 35/165 (21%), Positives = 71/165 (43%), Gaps = 4/165 (2%)

Query: 4232 EKTFEERQ--VLQRQGVIDHRPELKPKVIKEPETEWQQSVKRK-KNEEYYNKLQELENEQ 4288
            EK  +E Q  + Q+Q  ++ + E+   V  + E + ++  + K +NE    K++++E++ 
Sbjct: 492  EKQIQELQSKIRQQQEQLEQQREITDTVSTDLEEKAKELEEAKSENEAISGKMKDMESQL 551

Query: 4289 VIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIP 4348
                  L  +     +   KVT    + S+AQ  + N D       Q  Q ++++  +  
Sbjct: 552  TSIADELASTKEALKLSQHKVTELESSLSVAQLTQSNNDSNTLQQLQEKQSRISELEQEL 611

Query: 4349 DPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHK 4393
              ++ +    +  +   K   +  V D E  +K    E TE  HK
Sbjct: 612  ASNQLSYEELQTDLEFTKAELQSTVEDNEALKKQVE-ELTETIHK 655


>SB_6057| Best HMM Match : ig (HMM E-Value=7.3e-06)
          Length = 814

 Score = 36.3 bits (80), Expect = 0.61
 Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 22/154 (14%)

Query: 4653 TVQWYKGDKL-IKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLK 4711
            ++ WYK  +  + P KY  M       T+   E +  + G Y C A N       +  LK
Sbjct: 631  SITWYKDHRSRVVPDKYIDMLTCQRSLTIGSVEVY--EAGRYTCQARNIYASANDSCVLK 688

Query: 4712 VTQPDQADNLPALTPLRDIVVYEGQPAQFKTQITSKIKPTIQ--------WLREGALIPE 4763
            V     A N+  +   RD+V+ +G     K  + + +  T +        W + G L+P 
Sbjct: 689  VAP---AVNIMWM---RDLVI-DGVQIDHKVVLGTALNITCEVIHARGAWWQKNGLLLPH 741

Query: 4764 TPDFQMIHEGNNAVLLI----GNTYEEDTGTFTC 4793
                 M    NNA L++        + D G +TC
Sbjct: 742  NVTHFMRRADNNARLILHIWFNRVQKNDEGNYTC 775



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 943  VEWLKDGRPVEASSRITTFFNFGYVALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIV 1002
            + W KD R      +          +LTI SV V++AG YTC+A N    A  S  L + 
Sbjct: 632  ITWYKDHRSRVVPDKYIDMLTCQR-SLTIGSVEVYEAGRYTCQARNIYASANDSCVLKVA 690

Query: 1003 TKKDII 1008
               +I+
Sbjct: 691  PAVNIM 696



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 41/174 (23%), Positives = 74/174 (42%), Gaps = 22/174 (12%)

Query: 4534 DTKVTGTKPIDVYWLKNGK-KVQPDIRNKILEEDGTYTLLILEAYPQDSGKYECVAINSA 4592
            D+  T T+ + + W K+ + +V PD    +L    + T+  +E Y  ++G+Y C A N  
Sbjct: 622  DSTSTQTQ-VSITWYKDHRSRVVPDKYIDMLTCQRSLTIGSVEVY--EAGRYTCQARNIY 678

Query: 4593 GEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLK-DKIVAEGQAIEFSCKIVGKPL 4651
              A  +  CV+       K  P          +I+ ++ D  V  G A+  +C+++    
Sbjct: 679  ASA--NDSCVL-------KVAPAVNIMWMRDLVIDGVQIDHKVVLGTALNITCEVIHA-- 727

Query: 4652 PTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAF-----PEDEGDYKCVAYNS 4700
                W++ + L+ P       R AD     I   +       DEG+Y C+ Y +
Sbjct: 728  -RGAWWQKNGLLLPHNVTHFMRRADNNARLILHIWFNRVQKNDEGNYTCLGYRA 780



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 16/33 (48%), Positives = 20/33 (60%)

Query: 3617 LEIGGVYQRDAGLYTCKATNRHGEATVSCKLQV 3649
            L IG V   +AG YTC+A N +  A  SC L+V
Sbjct: 657  LTIGSVEVYEAGRYTCQARNIYASANDSCVLKV 689


>SB_43663| Best HMM Match : F-box (HMM E-Value=4e-07)
          Length = 717

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%)

Query: 3023 EKIQNL-EDSL-RKEPGQQPDDDTGRPPEFTTVFKDIVDISEGQIAHYEASLIPTGDQSM 3080
            E++ +L EDSL R+E    P++D+    E +++ KD+  I E  +   E S IP  D S+
Sbjct: 177  EQVSSLREDSLIREENSSIPEEDSSIKEEVSSIHKDVSTIREDSLIREENSSIPEEDSSI 236


>SB_42146| Best HMM Match : GYF (HMM E-Value=5.7e-15)
          Length = 924

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 43/200 (21%), Positives = 93/200 (46%), Gaps = 21/200 (10%)

Query: 4219 DETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSV--KRKKNEE 4276
            +E    ++ E  L++  EE +  ++Q   + +   + +V K+ E + QQ    KR++ ++
Sbjct: 617  EEEEMRRQQEQMLQRQREEEERRRQQEEAERQRREQEEVFKQQEQQRQQLELQKRQQEQQ 676

Query: 4277 YYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQ- 4335
               +LQ+ + E+  + + +R+   Q             A    Q+ +  + + +E+ +Q 
Sbjct: 677  RQQELQKRQQEEKQRMAEMRQQQQQ-------------ALLRLQQQQQEVQRRKEIQKQM 723

Query: 4336 RVQKKVTQKPRIPDPS--ESTVHGKEVHVAKQKQTQKEVVG-DKEITRKITSTETTEIEH 4392
             +Q+K+ QK ++ + S   ST     + +A+ +Q Q+E     +E  R I   +  E ++
Sbjct: 724  ELQQKLQQKRQVSNGSLWGSTSSPAALSLAEIQQQQEERERLQRERQRLILEQQEREQQN 783

Query: 4393 KAQTQERVVEGPVKPSKPPI 4412
            +A         PV P  PP+
Sbjct: 784  RAAAAGWGEHAPVGP--PPV 801


>SB_36901| Best HMM Match : I-set (HMM E-Value=7.3e-09)
          Length = 84

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 15/29 (51%), Positives = 20/29 (68%)

Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            D +   +AG YTC ATN+ GS TTT ++T
Sbjct: 53   DSVTRSEAGTYTCTATNEIGSDTTTVQVT 81



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 15/29 (51%), Positives = 19/29 (65%)

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            SVT  +AG YTC A N IG  TT+  +T+
Sbjct: 54   SVTRSEAGTYTCTATNEIGSDTTTVQVTV 82



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 2805 LKIEWFFNNKPLPSGTRYKSTHDFSYVSLDITHTY-EEDSGIYTCKATNSKGSATTS 2860
            LK+    +  P P+ T  +   + S  S+  + +    ++G YTC ATN  GS TT+
Sbjct: 21   LKLTCISDGYPAPTSTWSRDGEEVSQTSVYYSDSVTRSEAGTYTCTATNEIGSDTTT 77


>SB_28769| Best HMM Match : ig (HMM E-Value=1e-06)
          Length = 213

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 18/131 (13%)

Query: 451 MITNVTLSDSGV--VTCVARNKSGETAFQC-RLNVIEKEQVVAPKFVERFSTLNVREGEP 507
           M  N+ L   G+  +TCV  N +G    +   +NV EK   ++       +T+N  EG  
Sbjct: 37  MFHNILLDSVGIHLLTCVPINDAGVGENRSVSMNVTEKLPTIS--ITPLRATVN--EGSV 92

Query: 508 VVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQN 567
           VV    A+G  + +  W+KDGV             G  S+L +      D   Y C   +
Sbjct: 93  VVFTCLAIGFQSFKNFWKKDGV-----------FKGDGSSLTLSSVGTDDRGNYTCNVTS 141

Query: 568 VAGSTATRARL 578
             G+T   A L
Sbjct: 142 TCGTTMKTASL 152



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 13/34 (38%), Positives = 22/34 (64%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            +L+++S+  DD G YTC  T+  G  + TAS+ +
Sbjct: 121  SLTLSSVGTDDRGNYTCNVTSTCGTTMKTASLDV 154



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 13/39 (33%), Positives = 22/39 (56%)

Query: 968  ALTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKD 1006
            +LT+ SV   D G+YTC   +  G    +A+L ++ K +
Sbjct: 121  SLTLSSVGTDDRGNYTCNVTSTCGTTMKTASLDVIYKPE 159


>SB_25318| Best HMM Match : fn3 (HMM E-Value=2e-15)
          Length = 911

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 1825 EDS--SRYQRREDVEVAVNQAPRFITQLNGPTKLSEGQSAHYECRIEPYPDPNMRVEWYF 1882
            EDS  S+Y R   ++V V   P F+   +    + EGQ  +  C     P+PN+   W+ 
Sbjct: 368  EDSYISKYVR-STIQVVVTDRPEFVAVPSRVYTIPEGQDLNVPCSARGSPNPNITWLWWT 426

Query: 1883 NGKVL 1887
             GK +
Sbjct: 427  EGKAV 431



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 443 NESGNHALMITNVTLSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTL-N 501
           N   N  L++ N++  D GV  C    +      +   + I+      P+FV   S +  
Sbjct: 340 NNGFNTTLVVGNMSREDEGVFGCQVLVREDSYISKYVRSTIQVVVTDRPEFVAVPSRVYT 399

Query: 502 VREGEPVVLNARAVGTPTPRITW 524
           + EG+ + +   A G+P P ITW
Sbjct: 400 IPEGQDLNVPCSARGSPNPNITW 422



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 1/62 (1%)

Query: 1428 SRYKKTDIIDESVTIKPRFVTRPKSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGQPV 1487
            S+Y ++ I    VT +P FV  P  +  + EGQ ++  C      + N+   W+  G+ V
Sbjct: 373  SKYVRSTI-QVVVTDRPEFVAVPSRVYTIPEGQDLNVPCSARGSPNPNITWLWWTEGKAV 431

Query: 1488 TI 1489
             +
Sbjct: 432  VV 433



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 1160 SKFVEPMYQIEEISKSKPVFVQPLSNPPPVSEGKNIHLECRLEPMGDPTMRVEWFHNGRS 1219
            SK+V    Q+  +   +P FV   S    + EG+++++ C      +P +   W+  G++
Sbjct: 373  SKYVRSTIQV--VVTDRPEFVAVPSRVYTIPEGQDLNVPCSARGSPNPNITWLWWTEGKA 430

Query: 1220 VTVGS 1224
            V V S
Sbjct: 431  VVVAS 435



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query: 4111 PVFVSLPDAV-TVEEGEWARFCCRVTGHPKPRVMWL 4145
            P FV++P  V T+ EG+     C   G P P + WL
Sbjct: 388  PEFVAVPSRVYTIPEGQDLNVPCSARGSPNPNITWL 423


>SB_18127| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 963

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 15/36 (41%), Positives = 22/36 (61%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIED 2736
            TLS   + + D G YTC  TN LG A++T  + I++
Sbjct: 396  TLSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIDN 431



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 14/35 (40%), Positives = 19/35 (54%)

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS 1804
            L+  YV   D GTYTC   N LG A+ +  L + +
Sbjct: 397  LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIDN 431



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 13/34 (38%), Positives = 18/34 (52%)

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKVD 2070
            L   Y  + D GTY C  TN +G A+ T  + +D
Sbjct: 397  LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLID 430



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 14/33 (42%), Positives = 18/33 (54%)

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKV 2201
            L   Y  + D GTY C  TN+LG A+ T  L +
Sbjct: 397  LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLI 429



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 13/28 (46%), Positives = 16/28 (57%)

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTT 3782
            L   Y+ + D G YTC  TN+ GSA  T
Sbjct: 397  LSFTYVVSGDKGTYTCNVTNRLGSAIAT 424


>SB_58320| Best HMM Match : I-set (HMM E-Value=0.0099)
          Length = 88

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 510 LNARAVGTPTPRITWQKDG-VPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567
           L  +A G P P+ITW K G  PI       +    G S L +   + A D   Y+C A N
Sbjct: 18  LQCKARGVPLPQITWDKPGDQPITAG----VSPISGGSQLQVTTTQDAGDYEQYKCRASN 73

Query: 568 VAGS 571
           + GS
Sbjct: 74  LLGS 77


>SB_47230| Best HMM Match : I-set (HMM E-Value=0.0028)
          Length = 88

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567
           L  +A G P P+ITW K  G PI       +    G S L +   + A D   Y+C A N
Sbjct: 18  LQCKAGGVPLPQITWYKPGGQPITAG----VSPISGGSQLQVTTTQDAGDYGQYKCRASN 73

Query: 568 VAGS 571
           + GS
Sbjct: 74  LLGS 77


>SB_46724| Best HMM Match : I-set (HMM E-Value=6.1e-11)
          Length = 133

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 18/137 (13%)

Query: 445 SGNHALMITNVTLSDSGVVTCVARNK-SGETAFQCRLN-VIEKEQVVAPKFVERFSTLNV 502
           SGN        T +D+G   C A N  +G T  +     VI K +   P F+       V
Sbjct: 8   SGN-VFTKAGATKADTGQYVCTAVNTVTGNTQTRTASTYVIVKYK---PSFISNSPYQTV 63

Query: 503 REG-EPVVLNARAVGTPTPRITWQKDGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWY 561
            E  + + L   + G P P +TW +DGV +    +  ++     +         S+A  Y
Sbjct: 64  NETIDFLKLTCESDGYPAPTVTWSRDGVVV---SQTSVYYSNSVT--------RSEAGTY 112

Query: 562 QCTAQNVAGSTATRARL 578
            CTA N  GS  T  ++
Sbjct: 113 TCTATNEMGSDTTTVQV 129



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 14/23 (60%), Positives = 18/23 (78%)

Query: 3764 DAGEYTCRATNKWGSATTTAKIT 3786
            +AG YTC ATN+ GS TTT ++T
Sbjct: 108  EAGTYTCTATNEMGSDTTTVQVT 130



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 31/133 (23%), Positives = 58/133 (43%), Gaps = 22/133 (16%)

Query: 4580 DSGKYECVAINSAGEARCDAECVVSLPATKDKPKPQTKAANAPPEIIEPLKDKIVAEGQA 4639
            D+G+Y C A+N+            +    K KP   +  +N+P + +    D        
Sbjct: 21   DTGQYVCTAVNTV-TGNTQTRTASTYVIVKYKP---SFISNSPYQTVNETID-------F 69

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            ++ +C+  G P PTV W + D ++       +S+T+  Y+  ++ +   + G Y C A N
Sbjct: 70   LKLTCESDGYPAPTVTWSR-DGVV-------VSQTSVYYSNSVTRS---EAGTYTCTATN 118

Query: 4700 SAGRVTVAAKLKV 4712
              G  T   ++ V
Sbjct: 119  EMGSDTTTVQVTV 131



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 14/29 (48%), Positives = 19/29 (65%)

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            SVT  +AG YTC A N +G  TT+  +T+
Sbjct: 103  SVTRSEAGTYTCTATNEMGSDTTTVQVTV 131


>SB_41408| Best HMM Match : I-set (HMM E-Value=0.0042)
          Length = 88

 Score = 35.9 bits (79), Expect = 0.80
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567
           L  +A G P P+ITW K  G PI       +    G S L +   + A D   Y+C A N
Sbjct: 18  LQCKARGVPLPQITWYKPGGQPITAG----VSPISGGSQLQVTTTQDAGDFGQYKCRASN 73

Query: 568 VAGS 571
           + GS
Sbjct: 74  LLGS 77


>SB_53713| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 903

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 17/129 (13%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGD-KLIKPSKYFQMSRTADEYTLR-------------ISEA 4685
            I  +C  VG P P + W   D   +  + Y   +   D+  LR             I+++
Sbjct: 264  ITLTCTSVGTPTPLITWVLPDGSQVNSTHYITETEVLDDLELRTRLKRPQPGGSLLITDS 323

Query: 4686 FPEDEGDYKCVAYNSAGRVTVAAKLKVTQPDQADNLPALTPLRDIVVYEGQPAQFKTQIT 4745
               D G Y C+A N  G  TV+A + V + D  D + A   L D  V++      +++  
Sbjct: 324  REVDTGVYVCIARNVLGNDTVSANVTV-RKDLVD-VDASITLPD-EVFDDDLLDTESERY 380

Query: 4746 SKIKPTIQW 4754
             ++K T +W
Sbjct: 381  VELKTTFEW 389



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 23/136 (16%)

Query: 457 LSDSGVVTCVARNKSGETAFQCRLNVIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVG 516
           L D G VT VA  +  +    C +NV   +Q +  +        N  + E + L   +VG
Sbjct: 222 LKDCGYVTPVAVTRMWKVTDVC-MNVTNHKQTIYFQ--------NQGQEENITLTCTSVG 272

Query: 517 TPTPRITW-QKDG-----------VPIIPNPEL--RIHTDGGASTLDIPRAKASDAAWYQ 562
           TPTP ITW   DG             ++ + EL  R+       +L I  ++  D   Y 
Sbjct: 273 TPTPLITWVLPDGSQVNSTHYITETEVLDDLELRTRLKRPQPGGSLLITDSREVDTGVYV 332

Query: 563 CTAQNVAGSTATRARL 578
           C A+NV G+    A +
Sbjct: 333 CIARNVLGNDTVSANV 348


>SB_53232| Best HMM Match : OAR (HMM E-Value=0.92)
          Length = 806

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 9/144 (6%)

Query: 4266 QQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAK--SMAQRYE 4323
            ++ +KR K+++YY K +  +  QVI+  + R    +    G   T   + K  S  +R E
Sbjct: 37   KKEIKRAKDKDYYEKNRNKKIAQVIERRKARREETK----GKSRTRTEIKKAASKKRRKE 92

Query: 4324 DNLDQTEEVTEQR--VQKKVTQKPRIPDPSESTVHGKEVHVAKQK-QTQKEVVGDKEITR 4380
                  EE+  +R   ++K  ++ R          G+E    K   +  K     K +T 
Sbjct: 93   QRATAREELERKRQIAREKTRERVRRYRQKNKEEQGQEKKNLKNTGERFKNRTSKKRVTD 152

Query: 4381 KITSTETTEIEHKAQTQERVVEGP 4404
            K+        E KA+  E ++  P
Sbjct: 153  KVKDKLPQTPEKKAEVLETLINSP 176


>SB_39065| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 207

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 28/140 (20%), Positives = 63/140 (45%), Gaps = 2/140 (1%)

Query: 4232 EKTFEERQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQVIK 4291
            E+  E++Q  Q+Q   +   E + +  +E E E +Q  ++++ +E   + QE E EQ  +
Sbjct: 19   EQEQEQQQQQQQQEEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQE-QEQEQEQEQE 77

Query: 4292 ESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPS 4351
            + + +E   +     ++       +   Q  E   +Q +E  EQ  +++  Q+       
Sbjct: 78   QEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQE-QEQEQEQEQEQEQEQEQEQ 136

Query: 4352 ESTVHGKEVHVAKQKQTQKE 4371
            E     ++    +Q+Q Q++
Sbjct: 137  EQEQEQEQEQEQEQEQEQEQ 156



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 22/141 (15%), Positives = 65/141 (46%), Gaps = 1/141 (0%)

Query: 4259 KEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSM 4318
            ++ + + QQ  + ++ E+   + QE E EQ  ++ + +E   +     ++       +  
Sbjct: 23   EQQQQQQQQEEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQ 82

Query: 4319 AQRYEDNLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEI 4378
             Q  E   +Q +E  +++ Q++  ++ +  +  +     +E    ++++ ++E   ++E 
Sbjct: 83   EQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQEQ 142

Query: 4379 TRKITSTETTEIEHKAQTQER 4399
             ++    +  E E + Q Q+R
Sbjct: 143  EQEQEQEQEQEQEQQ-QQQQR 162


>SB_31717| Best HMM Match : I-set (HMM E-Value=2.9e-10)
          Length = 84

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 14/23 (60%), Positives = 18/23 (78%)

Query: 3764 DAGEYTCRATNKWGSATTTAKIT 3786
            +AG YTC ATN+ GS TTT ++T
Sbjct: 59   EAGTYTCTATNEMGSDTTTVQVT 81



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 14/29 (48%), Positives = 19/29 (65%)

Query: 973  SVTVHDAGHYTCRAYNAIGQATTSANLTI 1001
            SVT  +AG YTC A N +G  TT+  +T+
Sbjct: 54   SVTRSEAGTYTCTATNEMGSDTTTVQVTV 82


>SB_20109| Best HMM Match : I-set (HMM E-Value=2e-05)
          Length = 122

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 29/120 (24%), Positives = 49/120 (40%), Gaps = 10/120 (8%)

Query: 1717 MKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVALNMKYVN 1776
            MK +R+ E ++      +     P+ RV W R+G+ ++   R    H     AL+++ V 
Sbjct: 12   MKQVRLPEGESVDILCDVKSC--PRARVMWSRDGLVLQNQTR---RH-----ALSLRRVE 61

Query: 1777 PEDSGTYTCRAINELGEAVTSSTLFVQSKASLQLESQHESALQKIQQLEDSSRYQRREDV 1836
               +G Y C A NELG       + V S      +  H  + + +Q  +      R   V
Sbjct: 62   LSHTGIYECDAANELGSVRNKVLVIVTSCPEPASQPSHVESRRLMQSYQGQRAGNRASQV 121



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 10/80 (12%)

Query: 2777 ISHLNNIVCKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGTRYKSTHDFSYVSLDIT 2836
            +S +  +   EG+++   C+V+    P  ++ W  +   L + TR    H  S   ++++
Sbjct: 9    LSSMKQVRLPEGESVDILCDVKSC--PRARVMWSRDGLVLQNQTR---RHALSLRRVELS 63

Query: 2837 HTYEEDSGIYTCKATNSKGS 2856
            HT     GIY C A N  GS
Sbjct: 64   HT-----GIYECDAANELGS 78


>SB_52206| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 786

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 10/111 (9%)

Query: 3953 YTSEVYLTEDDLYDVDKKQPPRFVTQIQSQTSLVEMETTKFECQLAPVGDPNMKVEWFFN 4012
            +TS++ +  DDL     + PP  ++ I     + E +     CQ+ P    + +V W  N
Sbjct: 256  FTSDIAI--DDLRSSCTQVPPE-ISYISPSAKVREGQRFVLRCQVIPKNSSS-EVYWTRN 311

Query: 4013 GKPLLHKNRFTPIYDFGYVAMNFGWVYPEDSGEYLCRATNLYGMDETKAVI 4063
            G+ L +  R      +  +A       P  +G Y+C A+++YG D    ++
Sbjct: 312  GERLDNLTRTNDSVIYTQIAE------PSMAGTYVCVASSIYGEDRNSTIL 356



 Score = 35.1 bits (77), Expect = 1.4
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 7/86 (8%)

Query: 4512 VPPSFTLTAQNVNVTSGQLVRLDTKVTG-TKPIDVYWLKNGKKVQPDIRNKILEEDGTYT 4570
            VPP  +  + +  V  GQ   L  +V       +VYW +NG+++    R     +   YT
Sbjct: 272  VPPEISYISPSAKVREGQRFVLRCQVIPKNSSSEVYWTRNGERLDNLTRTN---DSVIYT 328

Query: 4571 LLILEAYPQDSGKYECVAINSAGEAR 4596
             +   A P  +G Y CVA +  GE R
Sbjct: 329  QI---AEPSMAGTYVCVASSIYGEDR 351



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 7/98 (7%)

Query: 3136 VKLECVDKSKGQKPRFTTHIQNIEGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQPMRHS 3195
            + ++ +  S  Q P   ++I     +++GQ     C V+P +    ++ W  NG+ + + 
Sbjct: 260  IAIDDLRSSCTQVPPEISYISPSAKVREGQRFVLRCQVIPKNSSS-EVYWTRNGERLDNL 318

Query: 3196 TRIKTVSDFGFVVLDIAYTQNHDSGEYVCRAYNKYGED 3233
            TR    ++   +   IA  +   +G YVC A + YGED
Sbjct: 319  TR----TNDSVIYTQIA--EPSMAGTYVCVASSIYGED 350



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 7/102 (6%)

Query: 1568 DMVDEVTTQAPICTTSLKNVEIKEGQRAHFERRLIPVSDATLKVEWYHNNKPLKSGSRFT 1627
            D+    T   P  +    + +++EGQR     ++IP + ++ +V W  N + L +    T
Sbjct: 264  DLRSSCTQVPPEISYISPSAKVREGQRFVLRCQVIPKNSSS-EVYWTRNGERLDN---LT 319

Query: 1628 ETNNFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAIV 1669
             TN+   +   I    P  +GTY C A +  GE   S I IV
Sbjct: 320  RTND-SVIYTQIAE--PSMAGTYVCVASSIYGEDRNSTILIV 358



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 13/98 (13%)

Query: 2107 QRPVFLTALTSLENLKEGDRAHFECRVEPINDPHLTIDWFHNGQKIRAGHRYRTTHDFGY 2166
            Q P  ++ ++    ++EG R    C+V P N     + W  NG+++        T+D   
Sbjct: 271  QVPPEISYISPSAKVREGQRFVLRCQVIPKNSSS-EVYWTRNGERL---DNLTRTND--- 323

Query: 2167 VALDILYTY-AEDS--GTYMCKATNKLGEAVNTCTLKV 2201
                ++YT  AE S  GTY+C A++  GE  N+  L V
Sbjct: 324  ---SVIYTQIAEPSMAGTYVCVASSIYGEDRNSTILIV 358


>SB_46304| Best HMM Match : Laminin_G_2 (HMM E-Value=0)
          Length = 645

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 14/27 (51%), Positives = 19/27 (70%)

Query: 2177 EDSGTYMCKATNKLGEAVNTCTLKVAG 2203
            ED+G Y+C+ATNK G A    T+K+ G
Sbjct: 6    EDAGMYICRATNKEGTAEGFATIKIKG 32



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 13/30 (43%), Positives = 19/30 (63%)

Query: 3622 VYQRDAGLYTCKATNRHGEATVSCKLQVKG 3651
            V   DAG+Y C+ATN+ G A     +++KG
Sbjct: 3    VTHEDAGMYICRATNKEGTAEGFATIKIKG 32



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 13/35 (37%), Positives = 24/35 (68%), Gaps = 3/35 (8%)

Query: 2833 LDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTG 2867
            +++TH   ED+G+Y C+ATN +G+A    +++  G
Sbjct: 1    MNVTH---EDAGMYICRATNKEGTAEGFATIKIKG 32



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 15/27 (55%), Positives = 17/27 (62%)

Query: 4041 EDSGEYLCRATNLYGMDETKAVIKTTG 4067
            ED+G Y+CRATN  G  E  A IK  G
Sbjct: 6    EDAGMYICRATNKEGTAEGFATIKIKG 32


>SB_27034| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 629

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 49/213 (23%), Positives = 90/213 (42%), Gaps = 14/213 (6%)

Query: 4262 ETEWQQSVKRKKNEEYYNKLQELENEQVIKES-RLRESTHQYAIPGDKVTSNTVAKSMAQ 4320
            E+E   S   K+ ++   K+QELE E + K+  ++   T   A P + +    +      
Sbjct: 298  ESEGHLSTHEKRQKKLKQKIQELEKENLSKKPWQMSGETGSKARPINSLLEEDL------ 351

Query: 4321 RYEDNLDQTEEVTEQRVQK-KVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEIT 4379
             ++        +TE+  Q  +   K RI D +   V  K   V +  + +K++  D+E  
Sbjct: 352  NFDHTAVAAPPITEETTQNLEDIIKQRIKDEAWDDVERKAKPVLQPYEYKKKMPLDQE-K 410

Query: 4380 RKITSTETTEIEHKAQTQERVVEGPVKPSKPPIFTK-KMQPCRVFEHEQARFEVEFDGEP 4438
             K++ ++  E E+  QT E   +   +  + P   + K    ++F    A     F  +P
Sbjct: 411  SKLSLSQIYEQEYLKQTSEPESKKAAEDEENPAHAEIKTMMTKLFTKLDALSNFHFTPKP 470

Query: 4439 L-PLIKWYRENFPIKNSPDFQIHTFSTKSILII 4470
            L P IK    N P+ N    +I   ST   +++
Sbjct: 471  LKPEIK-IVTNTPVINME--EIAPVSTSDAMLL 500


>SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 933

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 8/81 (9%)

Query: 2660 VYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFDFGL------VTLSINSLRNDDSG 2713
            + LE   + R  P  K+ W K G +    +R+KS   + L      +  SI S ++ D+G
Sbjct: 854  IRLECFTDGRPAP--KVTWSKVGDSQPDSSRVKSEILYDLDMRQIGLEYSIISAQSYDAG 911

Query: 2714 IYTCKATNLLGEAVSTASIKI 2734
             Y CKATN L  A     I +
Sbjct: 912  TYECKATNKLATASHRVQITV 932



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 8/87 (9%)

Query: 1714 TMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTT--MHDFGYVALN 1771
            T PM  +  A N     E      G P  +V W + G     S+R+ +  ++D     + 
Sbjct: 840  TFPMSSLTAAYNSTIRLEC--FTDGRPAPKVTWSKVGDSQPDSSRVKSEILYDLDMRQIG 897

Query: 1772 MKY----VNPEDSGTYTCRAINELGEA 1794
            ++Y        D+GTY C+A N+L  A
Sbjct: 898  LEYSIISAQSYDAGTYECKATNKLATA 924



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 8/93 (8%)

Query: 642 PLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRFTSIFRFGY------IS 695
           P+ S+TA     I  E   +  G P  K+ W K G S   SSR  S   +        + 
Sbjct: 842 PMSSLTAAYNSTIRLECFTD--GRPAPKVTWSKVGDSQPDSSRVKSEILYDLDMRQIGLE 899

Query: 696 LDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
             ++S    D+G Y C+A +    A  +  + V
Sbjct: 900 YSIISAQSYDAGTYECKATNKLATASHRVQITV 932



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 6/70 (8%)

Query: 3723 GDPTMRIDWFHNGRPFATGSRVHT--LNDFGFIALDIDY--IYAR--DAGEYTCRATNKW 3776
            G P  ++ W   G      SRV +  L D     + ++Y  I A+  DAG Y C+ATNK 
Sbjct: 862  GRPAPKVTWSKVGDSQPDSSRVKSEILYDLDMRQIGLEYSIISAQSYDAGTYECKATNKL 921

Query: 3777 GSATTTAKIT 3786
             +A+   +IT
Sbjct: 922  ATASHRVQIT 931



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 10/91 (10%)

Query: 3565 SDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVILEIGGVYQ 3624
            S L  + NS+   EC        + +V W   G      SRVK+   +   + +IG  Y 
Sbjct: 844  SSLTAAYNSTIRLEC--FTDGRPAPKVTWSKVGDSQPDSSRVKSEILYDLDMRQIGLEYS 901

Query: 3625 ------RDAGLYTCKATNRHGEATVSCKLQV 3649
                   DAG Y CKATN+   AT S ++Q+
Sbjct: 902  IISAQSYDAGTYECKATNK--LATASHRVQI 930


>SB_13773| Best HMM Match : TolA (HMM E-Value=0.042)
          Length = 1558

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 21/229 (9%)

Query: 4227 TETELEKTFEERQVLQRQGVIDHRP----ELKPKV--IKEPETEWQQSVKRKKNEEYYNK 4280
            TE EL  ++ E      +   ++R     E+  K+  IKE   +  ++ K+K +EE    
Sbjct: 1142 TEEELIASYAEDAERAAEAAKEYRERTMFEIAEKINSIKEQRRQQTEAQKKKMDEEIRRL 1201

Query: 4281 LQELENEQVIKESRLRE-STHQYAIPGDKVTSNTVAKSM--AQRYEDNLDQTEEVTEQRV 4337
              ELE E+  +E RL E  T + A    K+     A+ +  AQR      + E++ ++  
Sbjct: 1202 EAELEEERSREELRLAERETERVAKKMKKLQEEEAARQLNAAQRGMSE-QEREKLLKEHD 1260

Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQTQ 4397
            +        +    E T       +  +++ +K+    KEIT K    E   +E + + +
Sbjct: 1261 ENMAKFSENLKKEQERTKAALRERLEARRKKKKD-AAMKEIT-KAAKEEKEALEQQQREK 1318

Query: 4398 ERVV--EGPVK-----PSKP--PIFTKKMQPCRVFEHEQARFEVEFDGE 4437
               V  EG  +     PS+P  P  TK  +P R  +   A   V F  E
Sbjct: 1319 LTAVQKEGAYRMAATTPSRPRTPPTTKAGEPQRAVQGTMAEPFVPFSLE 1367


>SB_8750| Best HMM Match : Neuromodulin (HMM E-Value=5.7)
          Length = 247

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 3009 LIERTQHPKGTEGLEKIQNLEDSLRKEPGQQPDDDTGRPPEFTTVFKDIVDISE 3062
            L++  QHPK     ++ +N ED    E  +QPD D  + PE   V+K   +IS+
Sbjct: 170  LLDTKQHPKDVSEDKEEKNDEDQPETEESEQPDADEDK-PEMDEVYKPQDEISQ 222


>SB_5736| Best HMM Match : I-set (HMM E-Value=0.0048)
          Length = 449

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 10/91 (10%)

Query: 403 VTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGV 462
           V E +     C+ TGR    + W +N+  I+         N S + AL +   TL+ +G 
Sbjct: 3   VYENETVALKCKATGRAPLYIAWLLNNLVIK---------NNSLDTALALNVTTLNMTGT 53

Query: 463 VTCVARNKSGETAFQCRLNVIEKEQVVAPKF 493
           V CVA N  G  +      V +K   +  KF
Sbjct: 54  VNCVATNSLGSDSKSFHFRV-KKPYEMCAKF 83


>SB_47260| Best HMM Match : ig (HMM E-Value=4.3e-13)
          Length = 402

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 3/62 (4%)

Query: 694 ISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHVTPRATIERTSQHPETLQYIQQLEDY 753
           I L ++++  +DSG Y+CR     G A  +  L +TP  T+   SQ    LQY ++  D 
Sbjct: 205 ILLRVVNVTYRDSGWYSCRVFDKYGKAFKQGFLAITPAPTL---SQQDLQLQYTRRYADN 261

Query: 754 SK 755
            K
Sbjct: 262 PK 263



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 2969 VTLDLVDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKDNLIER 3012
            + L +V+V  RDSG Y+C+ ++K G+AF    +  T    L ++
Sbjct: 205  ILLRVVNVTYRDSGWYSCRVFDKYGKAFKQGFLAITPAPTLSQQ 248



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 22/103 (21%), Positives = 42/103 (40%), Gaps = 5/103 (4%)

Query: 423 VTWFINDRQIRDDYNHKILVNESGNHALMITNVTLSDSGVVTCVARNKSGETA-FQCRLN 481
           +TW+  +  +++   ++  +N      L+++N+ L+D G  TCV + +S  T      L 
Sbjct: 59  ITWYKYNEPLQE-VTYRDAIN---TRMLILSNLLLADGGRYTCVLKTESNRTLNTSYMLT 114

Query: 482 VIEKEQVVAPKFVERFSTLNVREGEPVVLNARAVGTPTPRITW 524
           + +  Q   P  +       V  G+            TP I W
Sbjct: 115 INDHSQNKKPSIITHSINQTVIIGKTATFTCTITSFSTPYIEW 157



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 6/104 (5%)

Query: 4653 TVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
            ++ WYK ++ ++   Y     T     L +S     D G Y CV    + R T+     +
Sbjct: 58   SITWYKYNEPLQEVTYRDAINTR---MLILSNLLLADGGRYTCVLKTESNR-TLNTSYML 113

Query: 4713 TQPDQADNL-PAL-TPLRDIVVYEGQPAQFKTQITSKIKPTIQW 4754
            T  D + N  P++ T   +  V  G+ A F   ITS   P I+W
Sbjct: 114  TINDHSQNKKPSIITHSINQTVIIGKTATFTCTITSFSTPYIEW 157


>SB_6962| Best HMM Match : I-set (HMM E-Value=0.0042)
          Length = 88

 Score = 35.1 bits (77), Expect = 1.4
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 510 LNARAVGTPTPRITWQKDG-VPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567
           L  +A G P+P+ITW K G  PI       +    G S L +   + A D   Y+C A N
Sbjct: 18  LQCKARGVPSPQITWYKPGDQPITAG----VSPISGGSQLQVTTTQDAGDYGQYKCRASN 73

Query: 568 VAGS 571
             GS
Sbjct: 74  RLGS 77


>SB_53159| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1540

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 4/63 (6%)

Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAKASDAAWYQCTAQNV 568
           L  +A G P+  ITW K  G PI    +L     GG+         A D   Y+C A N+
Sbjct: 18  LQCKARGVPSAHITWYKPGGQPITAEVKL---ISGGSQLQVTTTQDAGDYGQYKCRASNL 74

Query: 569 AGS 571
            GS
Sbjct: 75  LGS 77


>SB_44172| Best HMM Match : Pkinase_Tyr (HMM E-Value=6.3e-20)
          Length = 637

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 2701 TLSINSLRNDDSGIYTCKATNLLGEAVSTASIKI 2734
            TLS   + + D G YTC  TN LG A++T  + I
Sbjct: 120  TLSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLI 153



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 1770 LNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQS-KASLQLESQHESALQKIQQ 1823
            L+  YV   D GTYTC   N LG A+ +  L + + + +  L+   E+   K+++
Sbjct: 121  LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIGNVRITFLLKITSETYSSKLKE 175



 Score = 34.7 bits (76), Expect = 1.9
 Identities = 15/37 (40%), Positives = 19/37 (51%)

Query: 2169 LDILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHR 2205
            L   Y  + D GTY C  TN+LG A+ T  L +   R
Sbjct: 121  LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIGNVR 157



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 1/56 (1%)

Query: 3755 LDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEKIKE 3810
            L   Y+ + D G YTC  TN+ GSA  T  +     R I    ++       K+KE
Sbjct: 121  LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIGNVR-ITFLLKITSETYSSKLKE 175



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 1/55 (1%)

Query: 2037 LDILYAYAEDTGTYMCKATNAVGEAVTTSSVKV-DAKSGLYLDTLDEQRLKKIQE 2090
            L   Y  + D GTY C  TN +G A+ T  + + + +    L    E    K++E
Sbjct: 121  LSFTYVVSGDKGTYTCNVTNRLGSAIATRDLLIGNVRITFLLKITSETYSSKLKE 175


>SB_30807| Best HMM Match : I-set (HMM E-Value=7.8e-08)
          Length = 148

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 9/104 (8%)

Query: 399 QDRDVTEGKMTRFDCRVTGRPYPEVTWFINDRQIRDDYNHKILVNESGNHALMITNVTLS 458
           + RDV E K     C  +GRP P VTW +N        +   + + +G+  L +  +   
Sbjct: 18  RSRDVAEDKDFSITCSASGRPAPNVTW-VNKT------SGSPVAHGTGSAILSLLKIQRH 70

Query: 459 DSGVVTCVARN--KSGETAFQCRLNVIEKEQVVAPKFVERFSTL 500
            +GV  C A N  K G       +NV  +  V+    +   STL
Sbjct: 71  QAGVYQCQATNDVKRGAITQDFTINVQCEYNVMCYPDIFSVSTL 114


>SB_22350| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1967

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 31/154 (20%), Positives = 75/154 (48%), Gaps = 5/154 (3%)

Query: 4219 DETTQYQRTETELEKTFEE-RQVLQRQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEY 4277
            D+  ++ R +  LE+T  + ++V++R+G   ++   +   +++   E  +S ++   E  
Sbjct: 1806 DQEAKHNRQKNTLEQTVAKMKEVMERKGGDANKVNARVAELEKELKEKTKSAEKLVKEGT 1865

Query: 4278 YNKLQELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRV 4337
             +   E E +Q+ +E      T +  I   K+T+ +    +++ YE  ++++E + +   
Sbjct: 1866 LSVYIE-EKDQLQRELDALRKT-EAGIEVSKLTTTSSQVEISRDYE--IEKSEILVKLEQ 1921

Query: 4338 QKKVTQKPRIPDPSESTVHGKEVHVAKQKQTQKE 4371
            ++ V  K +    S  +   KE  + KQ+  +KE
Sbjct: 1922 KEGVIAKMKTQQKSSDSAAAKEKRLLKQQLKEKE 1955


>SB_21400| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1531

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 47/200 (23%), Positives = 90/200 (45%), Gaps = 13/200 (6%)

Query: 4230 ELEKTFEERQV-LQRQG-----VIDHRPELKPKV-IKEPETEWQQSVKRKKNEEYYNKLQ 4282
            +LE+   ERQ  LQ++      + D R  L+ +V + E E + +++  + +  E + KLQ
Sbjct: 770  KLEQALSERQTALQKEQERAREMQDSRLHLQQQVTLIEQEIDRERNASQLETNEMHQKLQ 829

Query: 4283 ELENEQVIKESRLRE-STHQYAIPGDKVTSNTVAKSMAQRYEDNLDQTEEVTEQRVQKKV 4341
            E   E   K S L+E S+    +  D  TS+     + Q  ++   Q +  + Q      
Sbjct: 830  EARAELEKKTSELKELSSTMREMHQDMKTSSASIVELEQLLQEARTQNDRHSVQLQTTDH 889

Query: 4342 TQKPRIPDPSESTVHGKEVHVAKQKQTQKEVVGDKEITRKITSTETTEIEHKAQ---TQE 4398
              K      S+ T    E+   K ++T++E + D++        E T++++  Q   TQ 
Sbjct: 890  AYKETKASLSQQTKRNGELE-EKLRRTEEE-LKDRDGQVAKLDNELTKLQNDFQDTITQL 947

Query: 4399 RVVEGPVKPSKPPIFTKKMQ 4418
            + +E  +  SK  +  K+ +
Sbjct: 948  KTLEDLLDTSKRVVEEKEQK 967


>SB_20351| Best HMM Match : I-set (HMM E-Value=1.9e-13)
          Length = 142

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 8/80 (10%)

Query: 4623 PEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRI 4682
            P I    KD I  E + ++ SC+  G     + W +GD +++       +R++D   L +
Sbjct: 59   PMIYPKPKDVIAYENEDVKLSCQATGDTPFHIAWLRGDVILQ-------NRSSDT-DLVL 110

Query: 4683 SEAFPEDEGDYKCVAYNSAG 4702
            S     D G Y C   NS G
Sbjct: 111  SAVKANDSGIYTCCTTNSLG 130



 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 8/84 (9%)

Query: 4728 RDIVVYEGQPAQFKTQITSKIKPTIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEED 4787
            +D++ YE +  +   Q T      I WLR   ++         +  ++  L++      D
Sbjct: 66   KDVIAYENEDVKLSCQATGDTPFHIAWLRGDVILQ--------NRSSDTDLVLSAVKAND 117

Query: 4788 TGTFTCRATTAAGQVETSAKLVVK 4811
            +G +TC  T + G    S  L+VK
Sbjct: 118  SGIYTCCTTNSLGSDSKSLVLLVK 141



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 10/93 (10%)

Query: 1711 PVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNGVPIEASNRLTTMHDFGYVAL 1770
            P+     KD+   EN+      +    GD    + WLR  V ++  NR +         L
Sbjct: 59   PMIYPKPKDVIAYENEDVKLSCQA--TGDTPFHIAWLRGDVILQ--NRSSDTD------L 108

Query: 1771 NMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQ 1803
             +  V   DSG YTC   N LG    S  L V+
Sbjct: 109  VLSAVKANDSGIYTCCTTNSLGSDSKSLVLLVK 141



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 26/93 (27%), Positives = 35/93 (37%), Gaps = 10/93 (10%)

Query: 3558 PEFTTTPSDLILSENSSAHFECRLIPVNDSSMRVEWFHNGKPLLTGSRVKTINDFGFVIL 3617
            P     P D+I  EN      C+     D+   + W   G  +L      T        L
Sbjct: 59   PMIYPKPKDVIAYENEDVKLSCQA--TGDTPFHIAWLR-GDVILQNRSSDTD-------L 108

Query: 3618 EIGGVYQRDAGLYTCKATNRHGEATVSCKLQVK 3650
             +  V   D+G+YTC  TN  G  + S  L VK
Sbjct: 109  VLSAVKANDSGIYTCCTTNSLGSDSKSLVLLVK 141



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 10/79 (12%)

Query: 1324 EGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVY 1383
            E  +V L C  Q  GD    + W   G  I        + + D V   L +V   DSG+Y
Sbjct: 72   ENEDVKLSC--QATGDTPFHIAWL-RGDVILQNR----SSDTDLV---LSAVKANDSGIY 121

Query: 1384 TCQATNQLGEAVTSCALRV 1402
            TC  TN LG    S  L V
Sbjct: 122  TCCTTNSLGSDSKSLVLLV 140


>SB_11517| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 240

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 3/72 (4%)

Query: 4225 QRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEW--QQSVKRKKNEEYYNKLQ 4282
            Q    ++E+  E  +VLQ Q   + +   + + +KE E EW  +Q+  R + EE+  K +
Sbjct: 159  QEAMEQMERNRETLRVLQLQSEANAKQREEERRLKELEAEWLKEQNAMRAQEEEFL-KQE 217

Query: 4283 ELENEQVIKESR 4294
            +L  ++  K +R
Sbjct: 218  KLRKQEAAKRAR 229


>SB_3226| Best HMM Match : RNA_pol_Rpb2_1 (HMM E-Value=0.021)
          Length = 1217

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 27/106 (25%), Positives = 54/106 (50%), Gaps = 8/106 (7%)

Query: 4198 KVIPRHDDYRGVLKNAPRPWYDETTQYQRTETELEKTFEERQVLQRQGVIDHRPELKPKV 4257
            ++IP  D +   L+ +    Y    ++Q  + +LE+  +ER  ++R+  I  R E K   
Sbjct: 699  RMIPDKDAFINTLRESRTEEYQ--AKFQAFQAKLEQVRKERLEVRRKRRIKDRKERKKIE 756

Query: 4258 IKEPETEWQQSVKRKKNEEYYNKLQELENEQVIKESRLRESTHQYA 4303
            ++E +   Q+  +RK+ EE     + +E E+  +E++ RE   + A
Sbjct: 757  MEEAKKREQEEKERKEKEE----KERIEREE--REAKEREYAERIA 796



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 6/100 (6%)

Query: 4225 QRTETELEKTFEERQVLQ---RQGVIDHRPELKPKVIKEPETEWQQSVKRKKNEEYYNKL 4281
            Q    + +K  E+ Q+ Q   R    +H+  L+ K + E   E+ +SV +++    Y K+
Sbjct: 485  QHDHIKAKKREEQEQMAQNYLRTARKEHKLMLERKTVIEARKEYLESVMQERERREYEKI 544

Query: 4282 --QELENEQVIKESRLRESTHQYAIPGDKVTSNTVAKSMA 4319
              Q++EN++  ++ RL E   Q  I   +     + K  A
Sbjct: 545  KKQKVENQEA-EQKRLDEERRQREIQRRRQELQDIEKRQA 583


>SB_26427| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 323

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 14/29 (48%), Positives = 19/29 (65%)

Query: 3758 DYIYARDAGEYTCRATNKWGSATTTAKIT 3786
            D +   +AG YTC ATN+ GS  TT ++T
Sbjct: 222  DSVTRSEAGTYTCTATNEMGSDATTVQVT 250


>SB_20144| Best HMM Match : E-MAP-115 (HMM E-Value=0.41)
          Length = 416

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 3/72 (4%)

Query: 4225 QRTETELEKTFEERQVLQRQGVIDHRPELKPKVIKEPETEW--QQSVKRKKNEEYYNKLQ 4282
            Q    ++E+  E  +VLQ Q   + +   + + +KE E EW  +Q+  R + EE+  K +
Sbjct: 119  QEAMEQMERNRETLRVLQLQSEANAKQREEERRLKELEAEWLKEQNAMRAQEEEFL-KQE 177

Query: 4283 ELENEQVIKESR 4294
            +L  ++  K +R
Sbjct: 178  KLRKQEAAKRAR 189


>SB_16370| Best HMM Match : I-set (HMM E-Value=0.0024)
          Length = 82

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 510 LNARAVGTPTPRITWQK-DGVPIIPNPELRIHTDGGASTLDIPRAK-ASDAAWYQCTAQN 567
           L  +A G P P+ITW K  G PI       +    G+S L +   + A D   Y+C A N
Sbjct: 11  LQCKARGVPLPQITWYKPGGQPITAG----VSPISGSSQLQVTTTQDAGDYGQYKCRASN 66

Query: 568 VAGS 571
             GS
Sbjct: 67  RLGS 70



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 2/65 (3%)

Query: 4640 IEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQMSRTADEYTLRISEAFPEDEGDYKCVAYN 4699
            +   CK  G PLP + WYK       +    +S ++        +A   D G YKC A N
Sbjct: 9    LSLQCKARGVPLPQITWYKPGGQPITAGVSPISGSSQLQVTTTQDA--GDYGQYKCRASN 66

Query: 4700 SAGRV 4704
              G V
Sbjct: 67   RLGSV 71


>SB_15350| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1126

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 11/130 (8%)

Query: 4253 LKPKVIKEPETEWQQSVKRKKNEEYYNKLQELENEQV--IKESRLRE--STHQYAIPGDK 4308
            ++ K  KE E   Q  ++R+K  E   K +E + ++V  ++  R RE     +  +  DK
Sbjct: 761  IEEKAKKERERMEQLEIQRQKKVEEQKKKREEKEKRVAELRAERQRELMEKKKQLLEKDK 820

Query: 4309 VTSNTV--AKSMAQRYED-----NLDQTEEVTEQRVQKKVTQKPRIPDPSESTVHGKEVH 4361
            + S     AK   +R ED      L +  ++  +R Q++ T+K R  +  E     +E+ 
Sbjct: 821  LISTLTEKAKKKKEREEDAKRRLRLQKKADLDARRKQEEETRKQRQLEQEEEAKRHQELL 880

Query: 4362 VAKQKQTQKE 4371
            + KQ+  ++E
Sbjct: 881  LRKQEFEEQE 890


>SB_50666| Best HMM Match : ig (HMM E-Value=2.8e-20)
          Length = 293

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 13/103 (12%)

Query: 626 PPGEEDRVYPPPQFIVPLKSVTAMEGGKIHFETRIEPVGDPTMKIEWLKNGQSIEASSRF 685
           P G     + PP    P  S TA+EG  +      +  G   +   WL++G+ + +    
Sbjct: 98  PRGTWGERHAPPMITRPTPSQTAVEGANVTLVC--DATGSSPLNTTWLRDGRIVASGE-- 153

Query: 686 TSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKAVLHV 728
                    +L + S+   + GEY C+A ++   A++ A + V
Sbjct: 154 ---------NLLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQV 187



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 14/118 (11%)

Query: 3690 EKPNPPRFTVEIKDNIDVPEGGPVHFDCRVEPVGDPTMRIDWFHNGRPFATGSRVHTLND 3749
            E+  PP  T        V EG  V   C  +  G   +   W  +GR  A+G        
Sbjct: 104  ERHAPPMITRPTPSQTAV-EGANVTLVC--DATGSSPLNTTWLRDGRIVASGEN------ 154

Query: 3750 FGFIALDIDYIYARDAGEYTCRATNKWGSATTTAKITCSAKRDIVLESQLPQGMSGEK 3807
                 L I  I   + GEY C+A N   +A +TA+I     + +V  + + +   GE+
Sbjct: 155  -----LLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQVDFGKPVVPAALMNRPTRGER 207



 Score = 33.9 bits (74), Expect = 3.2
 Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 16/154 (10%)

Query: 3829 PPKFITQIKSHTVEESEGVRFECRVEPKEDPKLRIEWYRNGKLLPSGHRYRTVYDMGFVS 3888
            PP       S T  E   V   C  +      L   W R+G+++ SG            +
Sbjct: 108  PPMITRPTPSQTAVEGANVTLVC--DATGSSPLNTTWLRDGRIVASGE-----------N 154

Query: 3889 LDILYVYAEDSGEYICRAVNDFGEDFTKATISC---KKLPDIILQNQVPRGMKRSEALTQ 3945
            L I  +  ++ GEY+C+A N      + A I     K +    L N+  RG +R      
Sbjct: 155  LLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQVDFGKPVVPAALMNRPTRGERRFAYWAL 214

Query: 3946 MEATIKKYTSEVYLTEDDLYDVDKKQPPRFVTQI 3979
             E  +  Y        + L+   +K+  R V++I
Sbjct: 215  AECILAYYVGTDEGVSEVLHVAGEKRLHRCVSRI 248



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 23/102 (22%), Positives = 38/102 (37%), Gaps = 11/102 (10%)

Query: 4611 KPKPQTKAANAPPEIIEPLKDKIVAEGQAIEFSCKIVGKPLPTVQWYKGDKLIKPSKYFQ 4670
            +P+      +APP I  P   +   EG  +   C   G       W +  +++       
Sbjct: 97   EPRGTWGERHAPPMITRPTPSQTAVEGANVTLVCDATGSSPLNTTWLRDGRIV------- 149

Query: 4671 MSRTADEYTLRISEAFPEDEGDYKCVAYNSAGRVTVAAKLKV 4712
                A    L I     ++EG+Y C A NS       A+++V
Sbjct: 150  ----ASGENLLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQV 187



 Score = 33.5 bits (73), Expect = 4.3
 Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 11/91 (12%)

Query: 4513 PPSFTLTAQNVNVTSGQLVRLDTKVTGTKPIDVYWLKNGKKVQPDIRNKILEEDGTYTLL 4572
            PP  T    +     G  V L    TG+ P++  WL++G+ V                LL
Sbjct: 108  PPMITRPTPSQTAVEGANVTLVCDATGSSPLNTTWLRDGRIVA-----------SGENLL 156

Query: 4573 ILEAYPQDSGKYECVAINSAGEARCDAECVV 4603
            I      + G+Y C A NS   A+  A+  V
Sbjct: 157  IPSIGRDEEGEYVCQAENSCSAAKSTAQIQV 187



 Score = 33.1 bits (72), Expect = 5.7
 Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 1311 PQFSRALHNIETVEGTNVHLECRLQPVGDQTMRVEWFCNGKPIKTGHRFRPAYEFDYVAL 1370
            P  +R   +   VEG NV L C     G   +   W  +G+ + +G             L
Sbjct: 109  PMITRPTPSQTAVEGANVTLVC--DATGSSPLNTTWLRDGRIVASGEN-----------L 155

Query: 1371 DLLSVYPEDSGVYTCQATNQLGEAVTSCALRVIAKKDLI 1409
             + S+  ++ G Y CQA N    A ++  ++V   K ++
Sbjct: 156  LIPSIGRDEEGEYVCQAENSCSAAKSTAQIQVDFGKPVV 194



 Score = 32.7 bits (71), Expect = 7.5
 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 14/100 (14%)

Query: 909  PEFKTPIKDQISIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVA 968
            P    P   Q ++ EG  A+     +  G S L   WL+DGR V +              
Sbjct: 109  PMITRPTPSQTAV-EG--ANVTLVCDATGSSPLNTTWLRDGRIVASGEN----------- 154

Query: 969  LTIKSVTVHDAGHYTCRAYNAIGQATTSANLTIVTKKDII 1008
            L I S+   + G Y C+A N+   A ++A + +   K ++
Sbjct: 155  LLIPSIGRDEEGEYVCQAENSCSAAKSTAQIQVDFGKPVV 194



 Score = 32.3 bits (70), Expect = 9.9
 Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 13/99 (13%)

Query: 2637 GVQQAPIFTTHLKSYDKLVEGQHVYLEAQVEPRTDPNLKIEWFKNGVTLTTGARLKSTFD 2696
            G + AP   T        VEG +V L       +   L   W ++G  + +G  L     
Sbjct: 103  GERHAPPMITRPTPSQTAVEGANVTLVCDATGSSP--LNTTWLRDGRIVASGENLL---- 156

Query: 2697 FGLVTLSINSLRNDDSGIYTCKATNLLGEAVSTASIKIE 2735
                   I S+  D+ G Y C+A N    A STA I+++
Sbjct: 157  -------IPSIGRDEEGEYVCQAENSCSAAKSTAQIQVD 188


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.316    0.133    0.391 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 164,020,062
Number of Sequences: 59808
Number of extensions: 7382525
Number of successful extensions: 40849
Number of sequences better than 10.0: 319
Number of HSP's better than 10.0 without gapping: 174
Number of HSP's successfully gapped in prelim test: 145
Number of HSP's that attempted gapping in prelim test: 19149
Number of HSP's gapped (non-prelim): 17308
length of query: 4814
length of database: 16,821,457
effective HSP length: 98
effective length of query: 4716
effective length of database: 10,960,273
effective search space: 51688647468
effective search space used: 51688647468
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 70 (32.3 bits)

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