Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000620-TA|BGIBMGA000620-PA|IPR005199|Glycoside hydrolase
family 79, N-terminal
(514 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC051321-1|AAH51321.1| 543|Homo sapiens heparanase protein. 243 1e-63
AY948074-1|AAX47106.1| 543|Homo sapiens heparanase protein. 243 1e-63
AF165154-1|AAD45379.1| 543|Homo sapiens heparanase protein. 243 1e-63
AF155510-1|AAD54941.1| 543|Homo sapiens heparanase precursor pr... 243 1e-63
AF152376-1|AAD45669.1| 543|Homo sapiens heparanase protein. 243 1e-63
AF144325-1|AAD41342.1| 543|Homo sapiens heparanase protein. 243 1e-63
AF084467-1|AAD54516.1| 545|Homo sapiens heparanase protein. 243 1e-63
AK222986-1|BAD96706.1| 543|Homo sapiens heparanase variant prot... 242 2e-63
BC112356-1|AAI12357.1| 592|Homo sapiens heparanase 2 protein. 222 3e-57
AL590036-2|CAH73137.1| 592|Homo sapiens heparanase 2 protein. 221 4e-57
AL445251-2|CAI16472.1| 592|Homo sapiens heparanase 2 protein. 221 4e-57
AL356268-1|CAH70448.1| 592|Homo sapiens heparanase 2 protein. 221 4e-57
AL356220-2|CAI17160.1| 592|Homo sapiens heparanase 2 protein. 221 4e-57
AL139243-1|CAI14146.1| 592|Homo sapiens heparanase 2 protein. 221 4e-57
AF282887-1|AAG23423.1| 592|Homo sapiens heparanase-like protein... 221 5e-57
AJ299719-1|CAC82491.1| 592|Homo sapiens heparanase 2 protein. 218 4e-56
AL590036-3|CAH73139.1| 548|Homo sapiens heparanase 2 protein. 189 2e-47
AL445251-3|CAI16474.1| 548|Homo sapiens heparanase 2 protein. 189 2e-47
AL356268-3|CAH70450.1| 548|Homo sapiens heparanase 2 protein. 189 2e-47
AL356220-3|CAI17162.1| 548|Homo sapiens heparanase 2 protein. 189 2e-47
AL139243-3|CAI14148.1| 548|Homo sapiens heparanase 2 protein. 189 2e-47
AJ299720-1|CAC82492.1| 548|Homo sapiens heparanase 3 protein. 186 2e-46
AL590036-1|CAH73138.1| 534|Homo sapiens heparanase 2 protein. 172 2e-42
AL445251-1|CAI16473.1| 534|Homo sapiens heparanase 2 protein. 172 2e-42
AL356268-2|CAH70449.1| 534|Homo sapiens heparanase 2 protein. 172 2e-42
AL356220-1|CAI17161.1| 534|Homo sapiens heparanase 2 protein. 172 2e-42
AL139243-2|CAI14147.1| 534|Homo sapiens heparanase 2 protein. 172 2e-42
AF282885-1|AAG23421.1| 480|Homo sapiens heparanase-like protein... 172 2e-42
AF282886-1|AAG23422.1| 534|Homo sapiens heparanase-like protein... 172 3e-42
AJ627581-1|CAF28887.1| 97|Homo sapiens heparanase protein. 67 2e-10
BC051718-1|AAH51718.1| 328|Homo sapiens UTY protein protein. 31 7.4
AF000995-1|AAC51842.1| 1240|Homo sapiens ubiquitous TPR motif, Y... 31 7.4
AF000994-1|AAC51841.1| 1347|Homo sapiens ubiquitous TPR motif, Y... 31 7.4
BC126394-1|AAI26395.1| 767|Homo sapiens chromosome 3 open readi... 31 9.7
BC035248-1|AAH35248.1| 600|Homo sapiens C3orf15 protein protein. 31 9.7
AL133066-1|CAB61389.1| 366|Homo sapiens hypothetical protein pr... 31 9.7
>BC051321-1|AAH51321.1| 543|Homo sapiens heparanase protein.
Length = 543
Score = 243 bits (594), Expect = 1e-63
Identities = 141/372 (37%), Positives = 203/372 (54%), Gaps = 13/372 (3%)
Query: 150 FCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLGNEPNSFQHVFNE 208
F + L L+F LNA+LR + WN NA+ L+++ K Y I W+LGNEPNSF +
Sbjct: 176 FANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADI 235
Query: 209 SVTPQILAKDFEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINV 268
+ L +DF +L KLL + ++++ + GPD +P+ + LK FL G I+
Sbjct: 236 FINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLK---SFLKAGGEVIDS 292
Query: 269 RSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMWLSETSSSYGGGA 327
+WH YYLN +TA EDF NP+ D+ ++ + + + +WL ETSS+YGGGA
Sbjct: 293 VTWHHYYLNGRTATREDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGA 352
Query: 328 PGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKPLPDWWISVLYKK 386
P LS+T+A +W+DKLGLSA+ I V+RQ F G G Y LVDEN PLPD+W+S+L+KK
Sbjct: 353 PLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKK 412
Query: 387 LVGNKVL--QVQCNCSRFQRLYIHCTNRKYTN-DTSAVTLYGVNLEMAKARFFLNGTALH 443
LVG KVL VQ + R R+Y+HCTN +TLY +NL +L
Sbjct: 413 LVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLH--NVTKYLRLPYPF 470
Query: 444 GDDLIIHEYIISAPSNNRKSKTILLNGWPLYY--ESNLHNLRPNIHRYGRYVSLPPYSIG 501
+ + + + SK++ LNG L + L L R G + LP +S
Sbjct: 471 SNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYS 530
Query: 502 FWVIKKTSITVC 513
F+VI+ + C
Sbjct: 531 FFVIRNAKVAAC 542
>AY948074-1|AAX47106.1| 543|Homo sapiens heparanase protein.
Length = 543
Score = 243 bits (594), Expect = 1e-63
Identities = 141/372 (37%), Positives = 203/372 (54%), Gaps = 13/372 (3%)
Query: 150 FCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLGNEPNSFQHVFNE 208
F + L L+F LNA+LR + WN NA+ L+++ K Y I W+LGNEPNSF +
Sbjct: 176 FANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADI 235
Query: 209 SVTPQILAKDFEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINV 268
+ L +DF +L KLL + ++++ + GPD +P+ + LK FL G I+
Sbjct: 236 FINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLK---SFLKAGGEVIDS 292
Query: 269 RSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMWLSETSSSYGGGA 327
+WH YYLN +TA EDF NP+ D+ ++ + + + +WL ETSS+YGGGA
Sbjct: 293 VTWHHYYLNGRTATREDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGA 352
Query: 328 PGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKPLPDWWISVLYKK 386
P LS+T+A +W+DKLGLSA+ I V+RQ F G G Y LVDEN PLPD+W+S+L+KK
Sbjct: 353 PLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKK 412
Query: 387 LVGNKVL--QVQCNCSRFQRLYIHCTNRKYTN-DTSAVTLYGVNLEMAKARFFLNGTALH 443
LVG KVL VQ + R R+Y+HCTN +TLY +NL +L
Sbjct: 413 LVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLH--NVTKYLRLPYPF 470
Query: 444 GDDLIIHEYIISAPSNNRKSKTILLNGWPLYY--ESNLHNLRPNIHRYGRYVSLPPYSIG 501
+ + + + SK++ LNG L + L L R G + LP +S
Sbjct: 471 SNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYS 530
Query: 502 FWVIKKTSITVC 513
F+VI+ + C
Sbjct: 531 FFVIRNAKVAAC 542
>AF165154-1|AAD45379.1| 543|Homo sapiens heparanase protein.
Length = 543
Score = 243 bits (594), Expect = 1e-63
Identities = 141/372 (37%), Positives = 203/372 (54%), Gaps = 13/372 (3%)
Query: 150 FCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLGNEPNSFQHVFNE 208
F + L L+F LNA+LR + WN NA+ L+++ K Y I W+LGNEPNSF +
Sbjct: 176 FANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADI 235
Query: 209 SVTPQILAKDFEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINV 268
+ L +DF +L KLL + ++++ + GPD +P+ + LK FL G I+
Sbjct: 236 FINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLK---SFLKAGGEVIDS 292
Query: 269 RSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMWLSETSSSYGGGA 327
+WH YYLN +TA EDF NP+ D+ ++ + + + +WL ETSS+YGGGA
Sbjct: 293 VTWHHYYLNGRTATREDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGA 352
Query: 328 PGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKPLPDWWISVLYKK 386
P LS+T+A +W+DKLGLSA+ I V+RQ F G G Y LVDEN PLPD+W+S+L+KK
Sbjct: 353 PLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKK 412
Query: 387 LVGNKVL--QVQCNCSRFQRLYIHCTNRKYTN-DTSAVTLYGVNLEMAKARFFLNGTALH 443
LVG KVL VQ + R R+Y+HCTN +TLY +NL +L
Sbjct: 413 LVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLH--NVTKYLRLPYPF 470
Query: 444 GDDLIIHEYIISAPSNNRKSKTILLNGWPLYY--ESNLHNLRPNIHRYGRYVSLPPYSIG 501
+ + + + SK++ LNG L + L L R G + LP +S
Sbjct: 471 SNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYS 530
Query: 502 FWVIKKTSITVC 513
F+VI+ + C
Sbjct: 531 FFVIRNAKVAAC 542
>AF155510-1|AAD54941.1| 543|Homo sapiens heparanase precursor
protein.
Length = 543
Score = 243 bits (594), Expect = 1e-63
Identities = 141/372 (37%), Positives = 203/372 (54%), Gaps = 13/372 (3%)
Query: 150 FCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLGNEPNSFQHVFNE 208
F + L L+F LNA+LR + WN NA+ L+++ K Y I W+LGNEPNSF +
Sbjct: 176 FANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADI 235
Query: 209 SVTPQILAKDFEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINV 268
+ L +DF +L KLL + ++++ + GPD +P+ + LK FL G I+
Sbjct: 236 FINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLK---SFLKAGGEVIDS 292
Query: 269 RSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMWLSETSSSYGGGA 327
+WH YYLN +TA EDF NP+ D+ ++ + + + +WL ETSS+YGGGA
Sbjct: 293 VTWHHYYLNGRTATREDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGA 352
Query: 328 PGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKPLPDWWISVLYKK 386
P LS+T+A +W+DKLGLSA+ I V+RQ F G G Y LVDEN PLPD+W+S+L+KK
Sbjct: 353 PLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKK 412
Query: 387 LVGNKVL--QVQCNCSRFQRLYIHCTNRKYTN-DTSAVTLYGVNLEMAKARFFLNGTALH 443
LVG KVL VQ + R R+Y+HCTN +TLY +NL +L
Sbjct: 413 LVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLH--NVTKYLRLPYPF 470
Query: 444 GDDLIIHEYIISAPSNNRKSKTILLNGWPLYY--ESNLHNLRPNIHRYGRYVSLPPYSIG 501
+ + + + SK++ LNG L + L L R G + LP +S
Sbjct: 471 SNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYS 530
Query: 502 FWVIKKTSITVC 513
F+VI+ + C
Sbjct: 531 FFVIRNAKVAAC 542
>AF152376-1|AAD45669.1| 543|Homo sapiens heparanase protein.
Length = 543
Score = 243 bits (594), Expect = 1e-63
Identities = 141/372 (37%), Positives = 203/372 (54%), Gaps = 13/372 (3%)
Query: 150 FCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLGNEPNSFQHVFNE 208
F + L L+F LNA+LR + WN NA+ L+++ K Y I W+LGNEPNSF +
Sbjct: 176 FANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADI 235
Query: 209 SVTPQILAKDFEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINV 268
+ L +DF +L KLL + ++++ + GPD +P+ + LK FL G I+
Sbjct: 236 FINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLK---SFLKAGGEVIDS 292
Query: 269 RSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMWLSETSSSYGGGA 327
+WH YYLN +TA EDF NP+ D+ ++ + + + +WL ETSS+YGGGA
Sbjct: 293 VTWHHYYLNGRTATREDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGA 352
Query: 328 PGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKPLPDWWISVLYKK 386
P LS+T+A +W+DKLGLSA+ I V+RQ F G G Y LVDEN PLPD+W+S+L+KK
Sbjct: 353 PLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKK 412
Query: 387 LVGNKVL--QVQCNCSRFQRLYIHCTNRKYTN-DTSAVTLYGVNLEMAKARFFLNGTALH 443
LVG KVL VQ + R R+Y+HCTN +TLY +NL +L
Sbjct: 413 LVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLH--NVTKYLRLPYPF 470
Query: 444 GDDLIIHEYIISAPSNNRKSKTILLNGWPLYY--ESNLHNLRPNIHRYGRYVSLPPYSIG 501
+ + + + SK++ LNG L + L L R G + LP +S
Sbjct: 471 SNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYS 530
Query: 502 FWVIKKTSITVC 513
F+VI+ + C
Sbjct: 531 FFVIRNAKVAAC 542
>AF144325-1|AAD41342.1| 543|Homo sapiens heparanase protein.
Length = 543
Score = 243 bits (594), Expect = 1e-63
Identities = 141/372 (37%), Positives = 203/372 (54%), Gaps = 13/372 (3%)
Query: 150 FCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLGNEPNSFQHVFNE 208
F + L L+F LNA+LR + WN NA+ L+++ K Y I W+LGNEPNSF +
Sbjct: 176 FANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADI 235
Query: 209 SVTPQILAKDFEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINV 268
+ L +DF +L KLL + ++++ + GPD +P+ + LK FL G I+
Sbjct: 236 FINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLK---SFLKAGGEVIDS 292
Query: 269 RSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMWLSETSSSYGGGA 327
+WH YYLN +TA EDF NP+ D+ ++ + + + +WL ETSS+YGGGA
Sbjct: 293 VTWHHYYLNGRTATREDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGA 352
Query: 328 PGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKPLPDWWISVLYKK 386
P LS+T+A +W+DKLGLSA+ I V+RQ F G G Y LVDEN PLPD+W+S+L+KK
Sbjct: 353 PLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKK 412
Query: 387 LVGNKVL--QVQCNCSRFQRLYIHCTNRKYTN-DTSAVTLYGVNLEMAKARFFLNGTALH 443
LVG KVL VQ + R R+Y+HCTN +TLY +NL +L
Sbjct: 413 LVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLH--NVTKYLRLPYPF 470
Query: 444 GDDLIIHEYIISAPSNNRKSKTILLNGWPLYY--ESNLHNLRPNIHRYGRYVSLPPYSIG 501
+ + + + SK++ LNG L + L L R G + LP +S
Sbjct: 471 SNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYS 530
Query: 502 FWVIKKTSITVC 513
F+VI+ + C
Sbjct: 531 FFVIRNAKVAAC 542
>AF084467-1|AAD54516.1| 545|Homo sapiens heparanase protein.
Length = 545
Score = 243 bits (594), Expect = 1e-63
Identities = 141/372 (37%), Positives = 203/372 (54%), Gaps = 13/372 (3%)
Query: 150 FCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLGNEPNSFQHVFNE 208
F + L L+F LNA+LR + WN NA+ L+++ K Y I W+LGNEPNSF +
Sbjct: 178 FANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADI 237
Query: 209 SVTPQILAKDFEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINV 268
+ L +DF +L KLL + ++++ + GPD +P+ + LK FL G I+
Sbjct: 238 FINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLK---SFLKAGGEVIDS 294
Query: 269 RSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMWLSETSSSYGGGA 327
+WH YYLN +TA EDF NP+ D+ ++ + + + +WL ETSS+YGGGA
Sbjct: 295 VTWHHYYLNGRTATREDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGA 354
Query: 328 PGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKPLPDWWISVLYKK 386
P LS+T+A +W+DKLGLSA+ I V+RQ F G G Y LVDEN PLPD+W+S+L+KK
Sbjct: 355 PLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKK 414
Query: 387 LVGNKVL--QVQCNCSRFQRLYIHCTNRKYTN-DTSAVTLYGVNLEMAKARFFLNGTALH 443
LVG KVL VQ + R R+Y+HCTN +TLY +NL +L
Sbjct: 415 LVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLH--NVTKYLRLPYPF 472
Query: 444 GDDLIIHEYIISAPSNNRKSKTILLNGWPLYY--ESNLHNLRPNIHRYGRYVSLPPYSIG 501
+ + + + SK++ LNG L + L L R G + LP +S
Sbjct: 473 SNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYS 532
Query: 502 FWVIKKTSITVC 513
F+VI+ + C
Sbjct: 533 FFVIRNAKVAAC 544
>AK222986-1|BAD96706.1| 543|Homo sapiens heparanase variant
protein.
Length = 543
Score = 242 bits (593), Expect = 2e-63
Identities = 141/372 (37%), Positives = 202/372 (54%), Gaps = 13/372 (3%)
Query: 150 FCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLGNEPNSFQHVFNE 208
F + L L+F LNA+LR + WN NA+ L+++ K Y I W+LGNEPNSF +
Sbjct: 176 FANCSGLDLIFGLNALLRTADLQWNSSNAQLLLDYCSSKGYNISWELGNEPNSFLKKADI 235
Query: 209 SVTPQILAKDFEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINV 268
+ L +DF +L KLL + ++++ + GPD +P+ + LK FL G I
Sbjct: 236 FINGSQLGEDFIQLHKLLRKSTFKNAKLYGPDVGQPRRKTAKMLK---SFLKAGGEVIGS 292
Query: 269 RSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMWLSETSSSYGGGA 327
+WH YYLN +TA EDF NP+ D+ ++ + + + +WL ETSS+YGGGA
Sbjct: 293 VTWHHYYLNGRTATREDFLNPDVLDIFISSVQKVFQVVESTRPGKKVWLGETSSAYGGGA 352
Query: 328 PGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKPLPDWWISVLYKK 386
P LS+T+A +W+DKLGLSA+ I V+RQ F G G Y LVDEN PLPD+W+S+L+KK
Sbjct: 353 PLLSDTFAAGFMWLDKLGLSARMGIEVVMRQVFFGAGNYHLVDENFDPLPDYWLSLLFKK 412
Query: 387 LVGNKVL--QVQCNCSRFQRLYIHCTNRKYTN-DTSAVTLYGVNLEMAKARFFLNGTALH 443
LVG KVL VQ + R R+Y+HCTN +TLY +NL +L
Sbjct: 413 LVGTKVLMASVQGSKRRKLRVYLHCTNTDNPRYKEGDLTLYAINLH--NVTKYLRLPYPF 470
Query: 444 GDDLIIHEYIISAPSNNRKSKTILLNGWPLYY--ESNLHNLRPNIHRYGRYVSLPPYSIG 501
+ + + + SK++ LNG L + L L R G + LP +S
Sbjct: 471 SNKQVDKYLLRPLGPHGLLSKSVQLNGLTLKMVDDQTLPPLMEKPLRPGSSLGLPAFSYS 530
Query: 502 FWVIKKTSITVC 513
F+VI+ + C
Sbjct: 531 FFVIRNAKVAAC 542
>BC112356-1|AAI12357.1| 592|Homo sapiens heparanase 2 protein.
Length = 592
Score = 222 bits (542), Expect = 3e-57
Identities = 129/395 (32%), Positives = 208/395 (52%), Gaps = 25/395 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESN 478
TL+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL +
Sbjct: 498 TLFIINLHRSRKKIKLTGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGT 554
Query: 479 LHNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L L+P R GR + +PP ++GF+V+K + C
Sbjct: 555 LPELKPRPLRAGRTLVIPPVTMGFFVVKNVNALAC 589
>AL590036-2|CAH73137.1| 592|Homo sapiens heparanase 2 protein.
Length = 592
Score = 221 bits (541), Expect = 4e-57
Identities = 129/395 (32%), Positives = 208/395 (52%), Gaps = 25/395 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESN 478
TL+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL +
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGT 554
Query: 479 LHNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L L+P R GR + +PP ++GF+V+K + C
Sbjct: 555 LPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 589
>AL445251-2|CAI16472.1| 592|Homo sapiens heparanase 2 protein.
Length = 592
Score = 221 bits (541), Expect = 4e-57
Identities = 129/395 (32%), Positives = 208/395 (52%), Gaps = 25/395 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESN 478
TL+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL +
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGT 554
Query: 479 LHNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L L+P R GR + +PP ++GF+V+K + C
Sbjct: 555 LPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 589
>AL356268-1|CAH70448.1| 592|Homo sapiens heparanase 2 protein.
Length = 592
Score = 221 bits (541), Expect = 4e-57
Identities = 129/395 (32%), Positives = 208/395 (52%), Gaps = 25/395 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESN 478
TL+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL +
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGT 554
Query: 479 LHNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L L+P R GR + +PP ++GF+V+K + C
Sbjct: 555 LPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 589
>AL356220-2|CAI17160.1| 592|Homo sapiens heparanase 2 protein.
Length = 592
Score = 221 bits (541), Expect = 4e-57
Identities = 129/395 (32%), Positives = 208/395 (52%), Gaps = 25/395 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESN 478
TL+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL +
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGT 554
Query: 479 LHNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L L+P R GR + +PP ++GF+V+K + C
Sbjct: 555 LPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 589
>AL139243-1|CAI14146.1| 592|Homo sapiens heparanase 2 protein.
Length = 592
Score = 221 bits (541), Expect = 4e-57
Identities = 129/395 (32%), Positives = 208/395 (52%), Gaps = 25/395 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESN 478
TL+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL +
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGT 554
Query: 479 LHNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L L+P R GR + +PP ++GF+V+K + C
Sbjct: 555 LPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 589
>AF282887-1|AAG23423.1| 592|Homo sapiens heparanase-like protein
HPA2c protein.
Length = 592
Score = 221 bits (540), Expect = 5e-57
Identities = 129/395 (32%), Positives = 208/395 (52%), Gaps = 25/395 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESN 478
TL+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL +
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGT 554
Query: 479 LHNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L L+P R GR + +PP ++GF+V+K + C
Sbjct: 555 LPELKPRPLRAGRTLVIPPVTMGFFVVKNVNALAC 589
>AJ299719-1|CAC82491.1| 592|Homo sapiens heparanase 2 protein.
Length = 592
Score = 218 bits (532), Expect = 4e-56
Identities = 128/395 (32%), Positives = 207/395 (52%), Gaps = 25/395 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ + + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNSADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESN 478
TL+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL +
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGT 554
Query: 479 LHNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L L+P R GR + +PP ++GF+V+K + C
Sbjct: 555 LPELKPRPLRAGRTLVIPPVTMGFFVVKNVNALAC 589
>AL590036-3|CAH73139.1| 548|Homo sapiens heparanase 2 protein.
Length = 548
Score = 189 bits (461), Expect = 2e-47
Identities = 112/345 (32%), Positives = 180/345 (52%), Gaps = 23/345 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKT 465
TL+ +NL ++ + L GT D ++H+Y++ KSKT
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKT 539
>AL445251-3|CAI16474.1| 548|Homo sapiens heparanase 2 protein.
Length = 548
Score = 189 bits (461), Expect = 2e-47
Identities = 112/345 (32%), Positives = 180/345 (52%), Gaps = 23/345 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKT 465
TL+ +NL ++ + L GT D ++H+Y++ KSKT
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKT 539
>AL356268-3|CAH70450.1| 548|Homo sapiens heparanase 2 protein.
Length = 548
Score = 189 bits (461), Expect = 2e-47
Identities = 112/345 (32%), Positives = 180/345 (52%), Gaps = 23/345 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKT 465
TL+ +NL ++ + L GT D ++H+Y++ KSKT
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKT 539
>AL356220-3|CAI17162.1| 548|Homo sapiens heparanase 2 protein.
Length = 548
Score = 189 bits (461), Expect = 2e-47
Identities = 112/345 (32%), Positives = 180/345 (52%), Gaps = 23/345 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKT 465
TL+ +NL ++ + L GT D ++H+Y++ KSKT
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKT 539
>AL139243-3|CAI14148.1| 548|Homo sapiens heparanase 2 protein.
Length = 548
Score = 189 bits (461), Expect = 2e-47
Identities = 112/345 (32%), Positives = 180/345 (52%), Gaps = 23/345 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ +F + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKT 465
TL+ +NL ++ + L GT D ++H+Y++ KSKT
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKT 539
>AJ299720-1|CAC82492.1| 548|Homo sapiens heparanase 3 protein.
Length = 548
Score = 186 bits (453), Expect = 2e-46
Identities = 111/345 (32%), Positives = 179/345 (51%), Gaps = 23/345 (6%)
Query: 138 IMTGNEWNQINDFCRKTNLKLLFSLNAMLRD-NHGWNEKNARELIEFSKHKQYAIDWQLG 196
I+T +++ + + L L+F+LNA+ R+ N+ WN +A L+++S K+Y I W+LG
Sbjct: 201 ILTARSLDKLYNSADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELG 260
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
NEPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 261 NEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 317
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKY-KNIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 318 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 377
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 378 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 437
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 438 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 497
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKT 465
TL+ +NL ++ + L GT D ++H+Y++ KSKT
Sbjct: 498 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKT 539
>AL590036-1|CAH73138.1| 534|Homo sapiens heparanase 2 protein.
Length = 534
Score = 172 bits (419), Expect = 2e-42
Identities = 106/334 (31%), Positives = 168/334 (50%), Gaps = 24/334 (7%)
Query: 198 EPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYMI 256
EPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 204 EPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALLD 260
Query: 257 EFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMW 315
F+ ++ +W Y++ + K+ DF D L QI +Q Y +W
Sbjct: 261 GFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIW 320
Query: 316 LSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKP 374
L ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N P
Sbjct: 321 LEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNP 380
Query: 375 LPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAVT 422
LPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++T
Sbjct: 381 LPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT 440
Query: 423 LYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESNL 479
L+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL + L
Sbjct: 441 LFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTL 497
Query: 480 HNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L+P R GR + +PP ++GF+V+K + C
Sbjct: 498 PELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 531
>AL445251-1|CAI16473.1| 534|Homo sapiens heparanase 2 protein.
Length = 534
Score = 172 bits (419), Expect = 2e-42
Identities = 106/334 (31%), Positives = 168/334 (50%), Gaps = 24/334 (7%)
Query: 198 EPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYMI 256
EPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 204 EPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALLD 260
Query: 257 EFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMW 315
F+ ++ +W Y++ + K+ DF D L QI +Q Y +W
Sbjct: 261 GFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIW 320
Query: 316 LSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKP 374
L ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N P
Sbjct: 321 LEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNP 380
Query: 375 LPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAVT 422
LPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++T
Sbjct: 381 LPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT 440
Query: 423 LYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESNL 479
L+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL + L
Sbjct: 441 LFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTL 497
Query: 480 HNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L+P R GR + +PP ++GF+V+K + C
Sbjct: 498 PELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 531
>AL356268-2|CAH70449.1| 534|Homo sapiens heparanase 2 protein.
Length = 534
Score = 172 bits (419), Expect = 2e-42
Identities = 106/334 (31%), Positives = 168/334 (50%), Gaps = 24/334 (7%)
Query: 198 EPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYMI 256
EPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 204 EPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALLD 260
Query: 257 EFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMW 315
F+ ++ +W Y++ + K+ DF D L QI +Q Y +W
Sbjct: 261 GFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIW 320
Query: 316 LSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKP 374
L ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N P
Sbjct: 321 LEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNP 380
Query: 375 LPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAVT 422
LPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++T
Sbjct: 381 LPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT 440
Query: 423 LYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESNL 479
L+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL + L
Sbjct: 441 LFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTL 497
Query: 480 HNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L+P R GR + +PP ++GF+V+K + C
Sbjct: 498 PELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 531
>AL356220-1|CAI17161.1| 534|Homo sapiens heparanase 2 protein.
Length = 534
Score = 172 bits (419), Expect = 2e-42
Identities = 106/334 (31%), Positives = 168/334 (50%), Gaps = 24/334 (7%)
Query: 198 EPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYMI 256
EPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 204 EPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALLD 260
Query: 257 EFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMW 315
F+ ++ +W Y++ + K+ DF D L QI +Q Y +W
Sbjct: 261 GFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIW 320
Query: 316 LSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKP 374
L ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N P
Sbjct: 321 LEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNP 380
Query: 375 LPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAVT 422
LPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++T
Sbjct: 381 LPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT 440
Query: 423 LYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESNL 479
L+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL + L
Sbjct: 441 LFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTL 497
Query: 480 HNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L+P R GR + +PP ++GF+V+K + C
Sbjct: 498 PELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 531
>AL139243-2|CAI14147.1| 534|Homo sapiens heparanase 2 protein.
Length = 534
Score = 172 bits (419), Expect = 2e-42
Identities = 106/334 (31%), Positives = 168/334 (50%), Gaps = 24/334 (7%)
Query: 198 EPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYMI 256
EPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 204 EPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALLD 260
Query: 257 EFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMW 315
F+ ++ +W Y++ + K+ DF D L QI +Q Y +W
Sbjct: 261 GFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIW 320
Query: 316 LSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKP 374
L ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N P
Sbjct: 321 LEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNP 380
Query: 375 LPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAVT 422
LPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++T
Sbjct: 381 LPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT 440
Query: 423 LYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESNL 479
L+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL + L
Sbjct: 441 LFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTL 497
Query: 480 HNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L+P R GR + +PP ++GF+V+K + C
Sbjct: 498 PELKPRPLRAGRTLVIPPVTMGFYVVKNVNALAC 531
>AF282885-1|AAG23421.1| 480|Homo sapiens heparanase-like protein
HPA2a protein.
Length = 480
Score = 172 bits (419), Expect = 2e-42
Identities = 106/335 (31%), Positives = 169/335 (50%), Gaps = 24/335 (7%)
Query: 197 NEPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYM 255
+EPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 149 DEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALL 205
Query: 256 IEFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPM 314
F+ ++ +W Y++ + K+ DF D L QI +Q Y +
Sbjct: 206 DGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKI 265
Query: 315 WLSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLK 373
WL ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N
Sbjct: 266 WLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFN 325
Query: 374 PLPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAV 421
PLPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++
Sbjct: 326 PLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSI 385
Query: 422 TLYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESN 478
TL+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL +
Sbjct: 386 TLFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGT 442
Query: 479 LHNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L L+P R GR + +PP ++GF+V+K + C
Sbjct: 443 LPELKPRPLRAGRTLVIPPVTMGFFVVKNVNALAC 477
>AF282886-1|AAG23422.1| 534|Homo sapiens heparanase-like protein
HPA2b protein.
Length = 534
Score = 172 bits (418), Expect = 3e-42
Identities = 106/334 (31%), Positives = 168/334 (50%), Gaps = 24/334 (7%)
Query: 198 EPNSFQHVFNESVTPQILAKDFEKLRKLLNH-NGYRHSLIVGPDTTRPQPHRPECLKYMI 256
EPN+++ + +V L KD+ +L+ LL Y + + GP+ RP R + +
Sbjct: 204 EPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRASLYGPNIGRP---RKNVIALLD 260
Query: 257 EFLGNGSHYINVRSWHQYYLNSKTAKLEDFWNPETFDLLRQQIETMQNQTKKYK-NIPMW 315
F+ ++ +W Y++ + K+ DF D L QI +Q Y +W
Sbjct: 261 GFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIW 320
Query: 316 LSETSSSYGGGAPGLSNTYAGSPLWIDKLGLSAKYNISTVIRQSFIG-GYYSLVDENLKP 374
L ++ GG LS++YA LW++ LG+ A I VIR SF GY LVD+N P
Sbjct: 321 LEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNP 380
Query: 375 LPDWWISVLYKKLVGNKVLQVQCNCSRFQ-----------RLYIHCTNRKYTNDT-SAVT 422
LPD+W+S+LYK+L+G KVL V + + R+Y HCTN N ++T
Sbjct: 381 LPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSIT 440
Query: 423 LYGVNLEMAKARFFLNGTALHGDDLIIHEYIISA-PSNNRKSKTILLNGWPLYY--ESNL 479
L+ +NL ++ + L GT D ++H+Y++ KSK++ LNG PL + L
Sbjct: 441 LFIINLHRSRKKIKLAGTL---RDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTL 497
Query: 480 HNLRPNIHRYGRYVSLPPYSIGFWVIKKTSITVC 513
L+P R GR + +PP ++GF+V+K + C
Sbjct: 498 PELKPRPLRAGRTLVIPPVTMGFFVVKNVNALAC 531
>AJ627581-1|CAF28887.1| 97|Homo sapiens heparanase protein.
Length = 97
Score = 66.9 bits (156), Expect = 2e-10
Identities = 34/74 (45%), Positives = 46/74 (62%), Gaps = 5/74 (6%)
Query: 285 DFWNPETFDLLRQQIETMQNQTKKYKNIPMWLSETSSSYGGGAPGLSNTYAGSPLWIDKL 344
DF+ E L+ ++ KK +WL ETSS+YGGGAP LS+T+A +W+DKL
Sbjct: 29 DFFTQEPLHLVSPSFLSVTRPGKK-----VWLGETSSAYGGGAPLLSDTFAAGFMWLDKL 83
Query: 345 GLSAKYNISTVIRQ 358
GLSA+ I V+RQ
Sbjct: 84 GLSARMGIEVVMRQ 97
>BC051718-1|AAH51718.1| 328|Homo sapiens UTY protein protein.
Length = 328
Score = 31.5 bits (68), Expect = 7.4
Identities = 11/26 (42%), Positives = 16/26 (61%)
Query: 136 FFIMTGNEWNQINDFCRKTNLKLLFS 161
+F++ + W +NDFC K NL L S
Sbjct: 94 WFVVPEDYWGVLNDFCEKNNLNFLMS 119
>AF000995-1|AAC51842.1| 1240|Homo sapiens ubiquitous TPR motif, Y
isoform protein.
Length = 1240
Score = 31.5 bits (68), Expect = 7.4
Identities = 11/26 (42%), Positives = 16/26 (61%)
Query: 136 FFIMTGNEWNQINDFCRKTNLKLLFS 161
+F++ + W +NDFC K NL L S
Sbjct: 1113 WFVVPEDYWGVLNDFCEKNNLNFLMS 1138
>AF000994-1|AAC51841.1| 1347|Homo sapiens ubiquitous TPR motif, Y
isoform protein.
Length = 1347
Score = 31.5 bits (68), Expect = 7.4
Identities = 11/26 (42%), Positives = 16/26 (61%)
Query: 136 FFIMTGNEWNQINDFCRKTNLKLLFS 161
+F++ + W +NDFC K NL L S
Sbjct: 1113 WFVVPEDYWGVLNDFCEKNNLNFLMS 1138
>BC126394-1|AAI26395.1| 767|Homo sapiens chromosome 3 open reading
frame 15 protein.
Length = 767
Score = 31.1 bits (67), Expect = 9.7
Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
Query: 219 FEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINVRSWHQYYLNS 278
FEK RK++N + + + Q R E LK ++ + +N++ +LN+
Sbjct: 263 FEKRRKMMNEMERKEWAFREQEIEKLQEIRLEVLKELLRKREENQNEVNMK-----HLNA 317
Query: 279 KTAKLEDFWNPETFDLLRQQIETMQNQTKKYKNI 312
+ +KL++ + + R + T++ K KNI
Sbjct: 318 RWSKLQEGKEAKMAKIQRTHVSTIRKLVGKRKNI 351
>BC035248-1|AAH35248.1| 600|Homo sapiens C3orf15 protein protein.
Length = 600
Score = 31.1 bits (67), Expect = 9.7
Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
Query: 219 FEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINVRSWHQYYLNS 278
FEK RK++N + + + Q R E LK ++ + +N++ +LN+
Sbjct: 263 FEKRRKMMNEMERKEWAFREQEIEKLQEIRLEVLKELLRKREENQNEVNMK-----HLNA 317
Query: 279 KTAKLEDFWNPETFDLLRQQIETMQNQTKKYKNI 312
+ +KL++ + + R + T++ K KNI
Sbjct: 318 RWSKLQEGKEAKMAKIQRTHVSTIRKLVGKRKNI 351
>AL133066-1|CAB61389.1| 366|Homo sapiens hypothetical protein
protein.
Length = 366
Score = 31.1 bits (67), Expect = 9.7
Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
Query: 219 FEKLRKLLNHNGYRHSLIVGPDTTRPQPHRPECLKYMIEFLGNGSHYINVRSWHQYYLNS 278
FEK RK++N + + + Q R E LK ++ + +N++ +LN+
Sbjct: 24 FEKRRKMMNEMERKEWAFREQEIEKLQEIRLEVLKELLRKREENQNEVNMK-----HLNA 78
Query: 279 KTAKLEDFWNPETFDLLRQQIETMQNQTKKYKNI 312
+ +KL++ + + R + T++ K KNI
Sbjct: 79 RWSKLQEGKEAKMAKIQRTHVSTIRKLVGKRKNI 112
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.137 0.431
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 78,838,595
Number of Sequences: 224733
Number of extensions: 3350126
Number of successful extensions: 6128
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 5913
Number of HSP's gapped (non-prelim): 44
length of query: 514
length of database: 73,234,838
effective HSP length: 93
effective length of query: 421
effective length of database: 52,334,669
effective search space: 22032895649
effective search space used: 22032895649
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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