Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000613-TA|BGIBMGA000613-PA|IPR002928|Myosin tail,
IPR009053|Prefoldin
(664 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 239 2e-62
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 239 2e-62
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 239 2e-62
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 239 2e-62
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 239 2e-62
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 238 4e-62
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 238 4e-62
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 238 4e-62
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 238 4e-62
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 238 5e-62
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 238 5e-62
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 238 5e-62
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 238 5e-62
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 238 5e-62
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 234 6e-61
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 234 6e-61
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 234 8e-61
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 233 2e-60
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 233 2e-60
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 233 2e-60
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 233 2e-60
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 233 2e-60
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 233 2e-60
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 233 2e-60
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 233 2e-60
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 233 2e-60
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 233 2e-60
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 233 2e-60
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 232 3e-60
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 231 6e-60
M25142-1|AAA60387.1| 389|Homo sapiens myosin heavy chain alpha-... 231 6e-60
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 230 1e-59
X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (... 230 1e-59
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 230 1e-59
M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac m... 230 1e-59
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 229 2e-59
M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myo... 229 2e-59
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 228 6e-59
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 225 4e-58
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 210 1e-53
S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy cha... 177 1e-43
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 151 1e-35
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 151 1e-35
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 151 1e-35
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 150 2e-35
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 149 2e-35
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 144 7e-34
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 144 7e-34
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 144 7e-34
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 144 7e-34
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 144 9e-34
BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein. 144 1e-33
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot... 144 1e-33
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 144 1e-33
AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens ... 142 3e-33
BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein. 142 5e-33
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 132 5e-30
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 132 5e-30
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 132 5e-30
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 132 5e-30
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 132 5e-30
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 131 9e-30
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 131 9e-30
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 128 8e-29
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 128 8e-29
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 128 8e-29
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 128 8e-29
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 126 3e-28
Z32858-1|CAA83687.1| 119|Homo sapiens fast 2a myosin heavy chai... 108 7e-23
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 108 7e-23
BC007877-1|AAH07877.2| 256|Homo sapiens MYH14 protein protein. 106 3e-22
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 104 1e-21
AL132825-5|CAI43044.1| 149|Homo sapiens myosin, heavy chain 7B,... 103 2e-21
AL132825-4|CAI43043.1| 122|Homo sapiens myosin, heavy chain 7B,... 103 2e-21
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 97 2e-19
AF149209-1|AAF73155.1| 167|Homo sapiens extraocular myosin heav... 97 2e-19
X04627-1|CAA28300.1| 258|Homo sapiens beta-myosin heavy chain p... 95 9e-19
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 89 4e-17
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 89 5e-17
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 89 5e-17
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 89 5e-17
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 89 5e-17
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 88 1e-16
S67247-1|AAB28952.1| 226|Homo sapiens smooth muscle myosin heav... 87 1e-16
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 87 2e-16
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 85 6e-16
AL132825-2|CAI43041.1| 144|Homo sapiens myosin, heavy chain 7B,... 85 8e-16
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 85 1e-15
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 85 1e-15
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 85 1e-15
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 85 1e-15
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 84 2e-15
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 81 1e-14
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 79 4e-14
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 79 5e-14
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 79 5e-14
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 79 5e-14
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 79 5e-14
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 79 5e-14
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 79 7e-14
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 78 9e-14
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 77 2e-13
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 77 2e-13
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 77 3e-13
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 77 3e-13
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 75 1e-12
AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein. 74 2e-12
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 74 2e-12
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 74 2e-12
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 74 2e-12
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 73 4e-12
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 73 4e-12
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 73 4e-12
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 72 6e-12
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 72 6e-12
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 71 2e-11
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 71 2e-11
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 70 2e-11
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 70 2e-11
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 70 2e-11
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 70 3e-11
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 70 3e-11
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 70 3e-11
AL590431-12|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein. 70 3e-11
AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens ... 70 3e-11
BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosoph... 69 4e-11
AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosoph... 69 4e-11
AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein. 69 4e-11
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 69 5e-11
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 69 7e-11
AL132825-3|CAI43040.1| 149|Homo sapiens myosin, heavy chain 7B,... 69 7e-11
AL132825-1|CAI43042.1| 143|Homo sapiens myosin, heavy chain 7B,... 69 7e-11
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 69 7e-11
X05631-1|CAA29119.1| 82|Homo sapiens myosin heavy chain protein. 68 9e-11
AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein pr... 68 9e-11
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 68 1e-10
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 68 1e-10
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 68 1e-10
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 68 1e-10
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 68 1e-10
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 67 2e-10
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 67 2e-10
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 67 2e-10
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 67 2e-10
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 67 2e-10
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 67 2e-10
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 67 2e-10
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 67 2e-10
Y09631-1|CAA70844.1| 758|Homo sapiens PIBF1 protein protein. 66 3e-10
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 66 3e-10
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 66 3e-10
BC051911-1|AAH51911.1| 757|Homo sapiens chromosome 13 open read... 66 3e-10
BC041806-1|AAH41806.1| 698|Homo sapiens C13orf24 protein protein. 66 3e-10
AL391384-3|CAI15673.1| 757|Homo sapiens RP11-505F3.1 protein. 66 3e-10
AL354720-1|CAI14869.1| 757|Homo sapiens RP11-505F3.1 protein. 66 3e-10
AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens ... 66 3e-10
AF330046-1|AAL37481.1| 757|Homo sapiens progesterone-induced bl... 66 3e-10
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 66 3e-10
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 66 3e-10
X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal ... 66 4e-10
L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory f... 66 4e-10
D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein. 66 4e-10
BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory... 66 4e-10
BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory... 66 4e-10
BC060037-1|AAH60037.1| 622|Homo sapiens KIAA1212 protein protein. 66 4e-10
BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-co... 66 4e-10
BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein. 66 4e-10
BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein. 66 4e-10
AL590431-11|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein. 66 4e-10
AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory... 66 4e-10
M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein. 65 7e-10
AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein. 65 7e-10
AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled co... 65 7e-10
M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein. 65 9e-10
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 64 1e-09
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 64 1e-09
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 64 1e-09
AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha stria... 64 1e-09
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 64 1e-09
X65873-1|CAA46703.1| 963|Homo sapiens kinesin heavy chain protein. 64 2e-09
BC126281-1|AAI26282.1| 963|Homo sapiens kinesin family member 5... 64 2e-09
BC126279-1|AAI26280.1| 963|Homo sapiens kinesin family member 5... 64 2e-09
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 64 2e-09
AL161932-2|CAH71618.1| 963|Homo sapiens kinesin family member 5... 64 2e-09
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 64 2e-09
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 63 3e-09
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 63 3e-09
AF223939-1|AAK00630.1| 2073|Homo sapiens ninein isotype 3 protein. 63 3e-09
AF223938-1|AAK00629.1| 2069|Homo sapiens ninein isotype 2 protein. 63 3e-09
AF223937-1|AAK00628.1| 2029|Homo sapiens ninein isotype 1 protein. 63 3e-09
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 63 3e-09
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 63 3e-09
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 63 3e-09
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 63 3e-09
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 63 3e-09
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 62 5e-09
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 62 5e-09
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 62 5e-09
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 62 5e-09
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 62 5e-09
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 62 5e-09
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 62 5e-09
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 62 6e-09
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 62 6e-09
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 62 6e-09
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 62 6e-09
AB209992-1|BAE06074.1| 2319|Homo sapiens DSP variant protein pro... 62 6e-09
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 62 6e-09
AL451082-2|CAH72276.1| 1194|Homo sapiens protein tyrosine phosph... 62 8e-09
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 62 8e-09
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 62 8e-09
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 61 1e-08
BC014109-1|AAH14109.1| 670|Homo sapiens leucine rich repeat con... 61 1e-08
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 61 1e-08
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 61 1e-08
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 61 1e-08
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 61 1e-08
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 61 1e-08
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein. 61 1e-08
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein. 61 1e-08
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 61 1e-08
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 61 1e-08
AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein pr... 61 1e-08
AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein. 61 1e-08
AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens ... 61 1e-08
BC009941-1|AAH09941.1| 550|Homo sapiens coiled-coil domain cont... 60 2e-08
BC008285-1|AAH08285.1| 550|Homo sapiens coiled-coil domain cont... 60 2e-08
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 60 2e-08
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 60 2e-08
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 60 2e-08
AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AB046860-1|BAB13466.1| 940|Homo sapiens KIAA1640 protein protein. 60 2e-08
X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for ... 60 3e-08
D86326-1|BAA25300.1| 962|Homo sapiens p115 protein. 60 3e-08
BC032654-1|AAH32654.1| 961|Homo sapiens vesicle docking protein... 60 3e-08
AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting p... 60 3e-08
AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting p... 60 3e-08
AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting p... 60 3e-08
AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting p... 60 3e-08
AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 60 3e-08
AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 60 3e-08
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 60 3e-08
AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein. 60 3e-08
AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein. 60 3e-08
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 59 4e-08
AL832010-1|CAD89917.1| 973|Homo sapiens hypothetical protein pr... 59 4e-08
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 59 4e-08
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 59 4e-08
AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens ... 59 6e-08
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 58 8e-08
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 58 1e-07
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 58 1e-07
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 58 1e-07
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 58 1e-07
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 58 1e-07
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 58 1e-07
BC029425-1|AAH29425.1| 272|Homo sapiens Unknown (protein for IM... 58 1e-07
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 58 1e-07
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 58 1e-07
AK097021-1|BAC04928.1| 512|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 58 1e-07
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 58 1e-07
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 58 1e-07
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 58 1e-07
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 58 1e-07
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 58 1e-07
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 58 1e-07
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 58 1e-07
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 58 1e-07
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 58 1e-07
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 58 1e-07
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 58 1e-07
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 58 1e-07
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 58 1e-07
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 58 1e-07
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 58 1e-07
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 57 2e-07
AY166853-1|AAO17292.1| 1317|Homo sapiens kinesin motor protein p... 57 2e-07
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 57 2e-07
AL118509-3|CAI43063.2| 1392|Homo sapiens chromosome 20 open read... 57 2e-07
AL118509-2|CAM28305.1| 1317|Homo sapiens chromosome 20 open read... 57 2e-07
AL117376-3|CAI43180.2| 1392|Homo sapiens chromosome 20 open read... 57 2e-07
AL117376-2|CAI43181.2| 1317|Homo sapiens chromosome 20 open read... 57 2e-07
AL049794-2|CAI22745.2| 1392|Homo sapiens chromosome 20 open read... 57 2e-07
AL049794-1|CAM28307.1| 1317|Homo sapiens chromosome 20 open read... 57 2e-07
AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens ... 57 2e-07
AK000142-1|BAA90971.1| 752|Homo sapiens protein ( Homo sapiens ... 57 2e-07
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 57 2e-07
AB046810-1|BAB13416.2| 1393|Homo sapiens KIAA1590 protein protein. 57 2e-07
Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of... 57 2e-07
X03445-1|CAA27174.1| 572|Homo sapiens protein ( Human mRNA for ... 57 2e-07
X03444-1|CAA27173.1| 702|Homo sapiens protein ( Human mRNA for ... 57 2e-07
S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein. 57 2e-07
M13451-1|AAA36164.1| 572|Homo sapiens protein ( Human lamin C m... 57 2e-07
D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein. 57 2e-07
BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural mainten... 57 2e-07
BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein. 57 2e-07
BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha) p... 57 2e-07
BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein. 57 2e-07
BC037991-1|AAH37991.1| 468|Homo sapiens CCDC46 protein protein. 57 2e-07
BC030505-1|AAH30505.1| 302|Homo sapiens HMMR protein protein. 57 2e-07
BC014507-1|AAH14507.1| 664|Homo sapiens lamin A/C protein. 57 2e-07
BC003162-1|AAH03162.1| 572|Homo sapiens lamin A/C protein. 57 2e-07
BC000511-1|AAH00511.1| 572|Homo sapiens lamin A/C protein. 57 2e-07
AY847597-1|AAW32540.1| 664|Homo sapiens lamin A/C transcript va... 57 2e-07
AY847596-1|AAW32539.1| 480|Homo sapiens lamin A/C transcript va... 57 2e-07
AY528714-1|ABB04050.1| 487|Homo sapiens rhabdomyosarcoma antige... 57 2e-07
AY357727-1|AAR29466.1| 614|Homo sapiens progerin protein. 57 2e-07
AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance ... 57 2e-07
AL135927-4|CAI15523.1| 614|Homo sapiens lamin A/C protein. 57 2e-07
AL135927-3|CAI15522.1| 664|Homo sapiens lamin A/C protein. 57 2e-07
AL135927-2|CAI15520.1| 465|Homo sapiens lamin A/C protein. 57 2e-07
AL135927-1|CAI15521.1| 572|Homo sapiens lamin A/C protein. 57 2e-07
AB046861-1|BAB13467.1| 718|Homo sapiens KIAA1641 protein protein. 57 2e-07
X04588-1|CAB37185.1| 248|Homo sapiens protein ( Human 2.5 kb mR... 56 3e-07
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 56 3e-07
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 56 3e-07
BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated mot... 56 3e-07
BC090932-1|AAH90932.1| 1377|Homo sapiens NIN protein protein. 56 3e-07
BC072428-1|AAH72428.1| 248|Homo sapiens tropomyosin 3 protein. 56 3e-07
BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein. 56 3e-07
BC015403-1|AAH15403.1| 248|Homo sapiens tropomyosin 3 protein. 56 3e-07
BC000771-1|AAH00771.1| 248|Homo sapiens tropomyosin 3 protein. 56 3e-07
AL590431-7|CAH71264.1| 248|Homo sapiens tropomyosin 3 protein. 56 3e-07
AL133410-3|CAI10976.1| 322|Homo sapiens tropomyosin 2 (beta) pr... 56 3e-07
AK055217-1|BAB70876.1| 688|Homo sapiens protein ( Homo sapiens ... 56 3e-07
AF212162-1|AAF23015.2| 2096|Homo sapiens ninein protein. 56 3e-07
AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant pr... 56 3e-07
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 56 3e-07
AB046785-1|BAB13391.2| 1313|Homo sapiens KIAA1565 protein protein. 56 3e-07
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 56 4e-07
X14487-1|CAA32649.1| 593|Homo sapiens protein ( Human gene for ... 56 4e-07
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 56 4e-07
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 56 4e-07
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 56 4e-07
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 56 4e-07
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 56 4e-07
BC034697-1|AAH34697.1| 584|Homo sapiens keratin 10 (epidermolyt... 56 4e-07
AY847595-1|AAW32538.1| 664|Homo sapiens lamin A/C transcript va... 56 4e-07
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 56 4e-07
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 56 4e-07
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 56 4e-07
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 56 4e-07
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 56 4e-07
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 56 4e-07
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 56 4e-07
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 56 4e-07
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 56 4e-07
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 56 4e-07
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 56 4e-07
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 56 4e-07
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 56 4e-07
AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1 va... 56 4e-07
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 56 5e-07
D11393-1|BAA01989.1| 208|Homo sapiens human non-muscle myosin h... 56 5e-07
BC068997-1|AAH68997.1| 541|Homo sapiens centrosomal protein 63k... 56 5e-07
BC012443-1|AAH12443.1| 717|Homo sapiens hook homolog 2 (Drosoph... 56 5e-07
AY640414-1|AAT68294.1| 284|Homo sapiens sarcomeric tropomyosin ... 56 5e-07
AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens ... 56 5e-07
AK056465-1|BAB71192.1| 703|Homo sapiens protein ( Homo sapiens ... 56 5e-07
AK023448-1|BAB14578.1| 541|Homo sapiens protein ( Homo sapiens ... 56 5e-07
M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein. 55 7e-07
M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein. 55 7e-07
M34458-1|AAA36162.1| 586|Homo sapiens protein ( Human lamin B m... 55 7e-07
M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyos... 55 7e-07
M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblas... 55 7e-07
L37747-1|AAC37575.1| 586|Homo sapiens lamin B1 protein. 55 7e-07
BC115701-1|AAI15702.1| 828|Homo sapiens SLMAP protein protein. 55 7e-07
BC103723-1|AAI03724.1| 586|Homo sapiens lamin B1 protein. 55 7e-07
BC033088-1|AAH33088.1| 465|Homo sapiens LMNA protein protein. 55 7e-07
BC012295-1|AAH12295.1| 586|Homo sapiens lamin B1 protein. 55 7e-07
BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 55 7e-07
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 55 7e-07
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 55 7e-07
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 55 7e-07
AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 55 7e-07
AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta) is... 55 7e-07
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 55 7e-07
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 55 7e-07
AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein. 55 7e-07
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 55 7e-07
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 55 7e-07
BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein. 55 9e-07
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 55 9e-07
AL590431-8|CAH71265.1| 232|Homo sapiens tropomyosin 3 protein. 55 9e-07
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 55 9e-07
AF450487-1|AAP97680.1| 1662|Homo sapiens kinesin-like protein KI... 55 9e-07
AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluroni... 55 9e-07
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 54 1e-06
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 54 1e-06
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 54 1e-06
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 54 1e-06
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 54 1e-06
BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein. 54 1e-06
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 54 1e-06
AY237538-1|AAP04415.1| 1304|Homo sapiens KIF27C protein. 54 1e-06
AL590431-5|CAH71266.1| 248|Homo sapiens tropomyosin 3 protein. 54 1e-06
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 54 1e-06
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 54 1e-06
AF474157-1|AAL84570.1| 247|Homo sapiens TPMsk3 protein. 54 1e-06
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 54 1e-06
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 54 1e-06
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 54 1e-06
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 54 2e-06
J04029-1|AAA60544.1| 561|Homo sapiens keratin 10 protein. 54 2e-06
BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein pr... 54 2e-06
BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3 (Drosoph... 54 2e-06
BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for IM... 54 2e-06
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 54 2e-06
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 54 2e-06
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 54 2e-06
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 54 2e-06
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 54 2e-06
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 54 2e-06
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 54 2e-06
AK096929-1|BAC04901.1| 567|Homo sapiens protein ( Homo sapiens ... 54 2e-06
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 54 2e-06
AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated microt... 54 2e-06
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 54 2e-06
AF044924-1|AAC09299.1| 719|Homo sapiens hook2 protein protein. 54 2e-06
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 54 2e-06
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 54 2e-06
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 54 2e-06
BC004165-1|AAH04165.1| 979|Homo sapiens NUMA1 protein protein. 54 2e-06
AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 2... 54 2e-06
AF273042-1|AAG34902.1| 685|Homo sapiens CTCL tumor antigen se1-... 54 2e-06
BC130385-1|AAI30386.1| 1197|Homo sapiens structural maintenance ... 53 3e-06
BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein. 53 3e-06
BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein. 53 3e-06
BC032571-1|AAH32571.1| 600|Homo sapiens RUN and FYVE domain con... 53 3e-06
BC011615-1|AAH11615.2| 739|Homo sapiens AZI1 protein protein. 53 3e-06
AY736182-1|AAU86898.1| 1989|Homo sapiens ninein isoform 6 protein. 53 3e-06
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 53 3e-06
AL354938-1|CAI16923.1| 1197|Homo sapiens structural maintenance ... 53 3e-06
AL161791-1|CAI16866.1| 1197|Homo sapiens structural maintenance ... 53 3e-06
AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AF361055-1|AAK50771.1| 600|Homo sapiens RUFY1 protein. 53 3e-06
AF302773-1|AAG33512.2| 2090|Homo sapiens ninein-Lm isoform protein. 53 3e-06
AB046821-1|BAB13427.1| 690|Homo sapiens KIAA1601 protein protein. 53 3e-06
AB029041-1|BAA83070.1| 1165|Homo sapiens KIAA1118 protein protein. 53 3e-06
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 53 4e-06
AL590431-3|CAH71261.1| 158|Homo sapiens tropomyosin 3 protein. 53 4e-06
AK023738-1|BAB14662.1| 475|Homo sapiens protein ( Homo sapiens ... 53 4e-06
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 53 4e-06
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 53 4e-06
X97053-1|CAA65765.1| 566|Homo sapiens plectin protein. 52 5e-06
X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for ... 52 5e-06
BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein. 52 5e-06
BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein. 52 5e-06
BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein. 52 5e-06
AK090540-1|BAC03473.1| 373|Homo sapiens protein ( Homo sapiens ... 52 5e-06
AF092563-1|AAC72360.1| 1197|Homo sapiens chromosome-associated p... 52 5e-06
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 52 5e-06
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 52 5e-06
BC017793-1|AAH17793.1| 331|Homo sapiens Unknown (protein for IM... 52 7e-06
AK128098-1|BAC87273.1| 1185|Homo sapiens protein ( Homo sapiens ... 52 7e-06
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 52 7e-06
AB051495-1|BAB21799.2| 1657|Homo sapiens KIAA1708 protein. 52 7e-06
X07695-1|CAA30534.1| 408|Homo sapiens cytokeratin 4 (408 AA) pr... 52 9e-06
BC101520-1|AAI01521.1| 1194|Homo sapiens protein tyrosine phosph... 52 9e-06
BC101518-1|AAI01519.1| 1194|Homo sapiens protein tyrosine phosph... 52 9e-06
BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil do... 52 9e-06
BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil do... 52 9e-06
BC042174-1|AAH42174.1| 534|Homo sapiens KRT4 protein protein. 52 9e-06
BC032703-1|AAH32703.1| 470|Homo sapiens peripherin protein. 52 9e-06
BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein. 52 9e-06
AY043326-1|AAL14196.1| 534|Homo sapiens keratin 4 protein. 52 9e-06
AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens ... 52 9e-06
AF265230-1|AAK58539.1| 975|Homo sapiens RING finger protein 20 ... 52 9e-06
AB014554-1|BAA31629.2| 1267|Homo sapiens KIAA0654 protein protein. 52 9e-06
BC128578-1|AAI28579.1| 751|Homo sapiens RRBP1 protein protein. 51 1e-05
BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein. 51 1e-05
AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1 p... 51 1e-05
AY114212-1|AAM47026.1| 467|Homo sapiens mutant desmin protein. 51 1e-05
AK092712-1|BAC03956.1| 183|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AK025336-1|BAB15114.1| 963|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 51 1e-05
AB051551-1|BAB21855.1| 1029|Homo sapiens KIAA1764 protein protein. 51 1e-05
M63391-1|AAA99221.1| 469|Homo sapiens desmin protein. 51 2e-05
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 51 2e-05
BX530088-1|CAI95784.1| 810|Homo sapiens GRIP1 associated protei... 51 2e-05
BC110585-1|AAI10586.1| 975|Homo sapiens ring finger protein 20 ... 51 2e-05
BC110584-1|AAI10585.1| 975|Homo sapiens ring finger protein 20 ... 51 2e-05
BC062740-1|AAH62740.1| 158|Homo sapiens TPM3 protein protein. 51 2e-05
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 51 2e-05
AL591377-3|CAH69963.1| 977|Homo sapiens ring finger protein 20 ... 51 2e-05
AL590431-4|CAH71262.1| 158|Homo sapiens tropomyosin 3 protein. 51 2e-05
AL353621-9|CAI14618.1| 977|Homo sapiens ring finger protein 20 ... 51 2e-05
AL133654-1|CAB63770.1| 833|Homo sapiens hypothetical protein pr... 51 2e-05
AK131470-1|BAD18615.1| 458|Homo sapiens protein ( Homo sapiens ... 51 2e-05
AK131255-1|BAD18434.1| 957|Homo sapiens protein ( Homo sapiens ... 51 2e-05
AK022532-1|BAB14081.1| 975|Homo sapiens protein ( Homo sapiens ... 51 2e-05
AK022300-1|BAB14005.1| 746|Homo sapiens protein ( Homo sapiens ... 51 2e-05
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do... 51 2e-05
AF312367-1|AAQ14554.1| 708|Homo sapiens La binding protein 1 pr... 51 2e-05
AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplasti... 51 2e-05
AF263742-1|AAF72196.1| 693|Homo sapiens golgin-like protein pro... 51 2e-05
AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion oncopro... 51 2e-05
M77663-1|AAA59199.1| 384|Homo sapiens keratin 10 protein. 50 2e-05
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 239 bits (585), Expect = 2e-62
Identities = 132/388 (34%), Positives = 225/388 (57%), Gaps = 12/388 (3%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
++RI EL + + ++ E E ++Q + Q ++E Q ++AE
Sbjct: 704 ILRIQLELTQVKSEIDRKIAEKDEEIEQLK---------RNYQRTVETMQ---SALDAEV 751
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ ++E R+KKK++ + E+E+ L AN+ + K ++ QL + Q H D+ R +
Sbjct: 752 RSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 811
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+Q + +RR L EVEE+R EQ R ++ EQ+ +S RV L N +L
Sbjct: 812 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 871
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+K K+E +L + ++ ++ +++ R A+E+ ++ T+ E L +EQ+ +E +KK+
Sbjct: 872 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 931
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
LE VK++ RL+E E A+ GGK+ I KLE RI+++E EL+ E++++ E++K LRK ER
Sbjct: 932 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYER 991
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
++KE+ Q EED+KN+ LQD ++K KV YKRQ E + + +T+ R+ Q ELE
Sbjct: 992 RVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEE 1051
Query: 618 AEDRADVAESNLSLIRAKHRTFVTTSTV 645
AE+RAD+AES ++ +RAK R F ++ V
Sbjct: 1052 AEERADIAESQVNKLRAKTRDFTSSRMV 1079
Score = 98.7 bits (235), Expect = 6e-20
Identities = 92/424 (21%), Positives = 187/424 (44%), Gaps = 19/424 (4%)
Query: 216 NLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQ 275
N +KN LA AL S+ + CD + E + + + + N+E+ Y
Sbjct: 469 NKAKNALAHALQSSR--HDCD--LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD 524
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQIT 335
+ E +++ L DS +Q +E +NA+ E + K++LQ ++
Sbjct: 525 AIQRTEELEEAKKKLAQRLQDSEEQ----VEAVNAKCASLE--------KTKQRLQGEVE 572
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L + ++ AN L K + L E +T +E Q +L+ +L + + L
Sbjct: 573 DLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKN 632
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
EE E R +++EQ+ + ++ E L S+ +IE E A + +E
Sbjct: 633 AYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEE 692
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
L + + R+Q EL + + E+ +IE +K++ + V+ + L + E
Sbjct: 693 AEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL-DAEV 751
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
+ R+ K+E + ++E++L R+ AET+K LR + QLK+ + ++ +
Sbjct: 752 RSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 811
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIR 633
L++ L ++ ++ + ++ E +Q+ + ++EL + +R + + N SLI
Sbjct: 812 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 871
Query: 634 AKHR 637
K +
Sbjct: 872 TKKK 875
Score = 82.2 bits (194), Expect = 5e-15
Identities = 57/271 (21%), Positives = 129/271 (47%), Gaps = 7/271 (2%)
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+K +L + + E++ +L + + Q ++Q+ + + + +Q ++ K +E
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
+ +E R + IN L++ K K+E E + + D D++ L ++ + ++K
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
+ E L E I K+ KK+L+ E ++ + E + + + SKLE +++D+E
Sbjct: 123 NLTEELSGLDETIAKLTREKKALQ-EAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLE 181
Query: 536 LELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKR 592
L++EK+ + + RK E LK E I+ E D++ L + L+K + +
Sbjct: 182 SSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQ---LDERLKKKDFEYCQLQS 238
Query: 593 QLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 239 KVEDEQTLGLQFQKKIKELQARIEELEEEIE 269
Score = 80.6 bits (190), Expect = 2e-14
Identities = 87/444 (19%), Positives = 192/444 (43%), Gaps = 19/444 (4%)
Query: 193 VQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVR 250
V++E+ FQ + L + + A+ +K S +R E ++E R+
Sbjct: 240 VEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE--RLE 297
Query: 251 ETSPTTCV-VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
E T + +N + A +L +L+E Q + + + K+ + + +L
Sbjct: 298 EAGGVTSTQIELNKKREA---EFLKLRRDLEEATLQHEAMVATL----RKKHADSVAELG 350
Query: 310 ARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
++ + ++K ++ + K + +++I +L S++ +K+ +L+K + QL+E +
Sbjct: 351 EQIDNLQ-RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKN 409
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
+E+QR L Q Q L+ ++EE Q R K++ QQ EE + ++ E
Sbjct: 410 EEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 469
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL-KHTVEHLHEEQERI 488
L+ + + ++ Y+E + + +E+ + ++ + +R
Sbjct: 470 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 529
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
++E KK L +++ ++E V A ++ +L+ ++D+ ++++ A
Sbjct: 530 EELEEAKKKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQGEVEDLMVDVERANSLAAAL 588
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSL-EKTSQKVSIYKRQLAEQEGMSQQSVTR 607
K R ++ L E +CEE Q L+ SL E S ++K + A +E + Q +
Sbjct: 589 DKKQRNFDKVLAEWKTKCEESQAE---LEASLKESRSLSTELFKLKNAYEEALDQLETVK 645
Query: 608 VRRFQRELEAAEDRADVAESNLSL 631
E E A+ +AE+ ++
Sbjct: 646 RENKNLEQEIADLTEQIAENGKTI 669
Score = 62.1 bits (144), Expect = 6e-09
Identities = 68/340 (20%), Positives = 157/340 (46%), Gaps = 16/340 (4%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +I+++ R E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 60 QLEAKIKEVTERA-EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 118
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG-EVEEIRGNYEQALRVKRSVE 415
+ LTE + DE +L T ++ + + Q+L + EE + N + K +E
Sbjct: 119 NKVKNLTEELSGLDETIAKL--TREKKALQEAHQQALDDLQAEEDKVN--SLNKTKSKLE 174
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
QQ E+ ++ + + + V+L +K K+E +L + ++ + + DER ++ E
Sbjct: 175 QQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYC 234
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK--RIISKLEARIKD 533
+ +EQ ++ + K L+ ++ + EE+EA K + S +++
Sbjct: 235 QLQSKVEDEQTLGLQFQKKIKELQARIEELE---EEIEAERATRAKTEKQRSDYARELEE 291
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKR 592
+ L+E + I++ +K+E + ++ EE ++ +++ +K + V+
Sbjct: 292 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGE 351
Query: 593 QLAEQEGMSQQSVTRVRRFQREL-EAAEDRADVAESNLSL 631
Q+ + + Q+ F+ E+ + + V++S +L
Sbjct: 352 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 391
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 239 bits (585), Expect = 2e-62
Identities = 132/388 (34%), Positives = 225/388 (57%), Gaps = 12/388 (3%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
++RI EL + + ++ E E ++Q + Q ++E Q ++AE
Sbjct: 1559 ILRIQLELTQVKSEIDRKIAEKDEEIEQLK---------RNYQRTVETMQ---SALDAEV 1606
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ ++E R+KKK++ + E+E+ L AN+ + K ++ QL + Q H D+ R +
Sbjct: 1607 RSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 1666
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+Q + +RR L EVEE+R EQ R ++ EQ+ +S RV L N +L
Sbjct: 1667 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 1726
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+K K+E +L + ++ ++ +++ R A+E+ ++ T+ E L +EQ+ +E +KK+
Sbjct: 1727 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1786
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
LE VK++ RL+E E A+ GGK+ I KLE RI+++E EL+ E++++ E++K LRK ER
Sbjct: 1787 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYER 1846
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
++KE+ Q EED+KN+ LQD ++K KV YKRQ E + + +T+ R+ Q ELE
Sbjct: 1847 RVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEE 1906
Query: 618 AEDRADVAESNLSLIRAKHRTFVTTSTV 645
AE+RAD+AES ++ +RAK R F ++ V
Sbjct: 1907 AEERADIAESQVNKLRAKTRDFTSSRMV 1934
Score = 100 bits (239), Expect = 2e-20
Identities = 92/424 (21%), Positives = 188/424 (44%), Gaps = 19/424 (4%)
Query: 216 NLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQ 275
N +KN LA AL S+ + CD + E + + + + N+E+ Y
Sbjct: 1324 NKAKNALAHALQSSR--HDCD--LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD 1379
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQIT 335
+ E +++ + L DS +Q +E +NA+ E + K++LQ ++
Sbjct: 1380 AIQRTEELEEAQEKLAQRLQDSEEQ----VEAVNAKCASLE--------KTKQRLQGEVE 1427
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L + ++ AN L K + L E +T +E Q +L+ +L + + L
Sbjct: 1428 DLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKN 1487
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
EE E R +++EQ+ + ++ E L S+ +IE E A + +E
Sbjct: 1488 AYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEE 1547
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
L + + R+Q EL + + E+ +IE +K++ + V+ + L + E
Sbjct: 1548 AEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL-DAEV 1606
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
+ R+ K+E + ++E++L R+ AET+K LR + QLK+ + ++ +
Sbjct: 1607 RSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 1666
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIR 633
L++ L ++ ++ + ++ E +Q+ + ++EL + +R + + N SLI
Sbjct: 1667 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 1726
Query: 634 AKHR 637
K +
Sbjct: 1727 TKKK 1730
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/298 (21%), Positives = 140/298 (46%), Gaps = 8/298 (2%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K +++ +K +L + + E++ +L + + Q
Sbjct: 832 KLFFKIKPLLKSAET-EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQL 890
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++Q+ + + + +Q ++ K +E + +E R + IN L++ K K+E E +
Sbjct: 891 QVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 950
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVR 508
+ D D++ L ++ + ++K+ E L E I K+ KK+L+ E ++
Sbjct: 951 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQ-EAHQQALD 1009
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK---EVIIQ 565
+ E + + + SKLE +++D+E L++EK+ + + RK E LK E I+
Sbjct: 1010 DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD 1069
Query: 566 CEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
E D++ L + L+K + + ++ +++ + Q +++ Q +E E+ +
Sbjct: 1070 LENDKQQ---LDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIE 1124
Score = 77.4 bits (182), Expect = 2e-13
Identities = 85/444 (19%), Positives = 192/444 (43%), Gaps = 19/444 (4%)
Query: 193 VQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVR 250
V++E+ FQ + L + + A+ +K S +R E ++E R+
Sbjct: 1095 VEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE--RLE 1152
Query: 251 ETSPTTCV-VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
E T + +N + A +L +L+E Q + + + K+ + + +L
Sbjct: 1153 EAGGVTSTQIELNKKREA---EFLKLRRDLEEATLQHEAMVATL----RKKHADSVAELG 1205
Query: 310 ARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
++ + ++K ++ + K + +++I +L S++ +K+ +L+K + QL+E +
Sbjct: 1206 EQIDNLQ-RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKN 1264
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
+E+QR L Q Q L+ ++EE Q R K++ QQ EE + ++ E
Sbjct: 1265 EEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 1324
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL-KHTVEHLHEEQERI 488
L+ + + ++ Y+E + + +E+ + ++ + +R
Sbjct: 1325 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 1384
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
++E ++ L +++ ++E V A ++ +L+ ++D+ ++++ A
Sbjct: 1385 EELEEAQEKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQGEVEDLMVDVERANSLAAAL 1443
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSL-EKTSQKVSIYKRQLAEQEGMSQQSVTR 607
K R ++ L E +CEE Q L+ SL E S ++K + A +E + Q +
Sbjct: 1444 DKKQRNFDKVLAEWKTKCEESQAE---LEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
Query: 608 VRRFQRELEAAEDRADVAESNLSL 631
E E A+ +AE+ ++
Sbjct: 1501 RENKNLEQEIADLTEQIAENGKTI 1524
Score = 62.1 bits (144), Expect = 6e-09
Identities = 68/340 (20%), Positives = 157/340 (46%), Gaps = 16/340 (4%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +I+++ R E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 915 QLEAKIKEVTERA-EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 973
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG-EVEEIRGNYEQALRVKRSVE 415
+ LTE + DE +L T ++ + + Q+L + EE + N + K +E
Sbjct: 974 NKVKNLTEELSGLDETIAKL--TREKKALQEAHQQALDDLQAEEDKVN--SLNKTKSKLE 1029
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
QQ E+ ++ + + + V+L +K K+E +L + ++ + + DER ++ E
Sbjct: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYC 1089
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK--RIISKLEARIKD 533
+ +EQ ++ + K L+ ++ + EE+EA K + S +++
Sbjct: 1090 QLQSKVEDEQTLGLQFQKKIKELQARIEELE---EEIEAERATRAKTEKQRSDYARELEE 1146
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKR 592
+ L+E + I++ +K+E + ++ EE ++ +++ +K + V+
Sbjct: 1147 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGE 1206
Query: 593 QLAEQEGMSQQSVTRVRRFQREL-EAAEDRADVAESNLSL 631
Q+ + + Q+ F+ E+ + + V++S +L
Sbjct: 1207 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 1246
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 239 bits (585), Expect = 2e-62
Identities = 122/342 (35%), Positives = 206/342 (60%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
D K+ I I + ++AE + +++ R+KKK++ + E+E+ L+ AN+ + +
Sbjct: 1588 DQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1647
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ L + Q H D+ R + +Q + +RR L E+EE+R EQ R ++ E
Sbjct: 1648 RNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1707
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ ++ RV L N +L ++K K+E +++ + + ++I +E R A+E+ ++ T+
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAA 1767
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK+LE VK++ RL+E E A+ GGK+ I KLEAR++++E
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE 1827
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
E++ E++R+ E +K LRK ER++KE+ Q EED+KNI LQD ++K KV YKRQ
Sbjct: 1828 GEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1887
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E S ++++ RR Q ELE AE+RAD+AES ++ +R K R
Sbjct: 1888 EAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
Score = 89.4 bits (212), Expect = 4e-17
Identities = 111/546 (20%), Positives = 239/546 (43%), Gaps = 46/546 (8%)
Query: 147 QEIEKELDLYEKEVN-LGSELR--QKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
Q++EKE + E++ L S + KA K +A+ L E + + +R+ D
Sbjct: 1219 QKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIN-DL 1277
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
A R + + S+ + K + S+ ++ T+ I E R E ++ +
Sbjct: 1278 TAQRARLQTESGEYSRQLDEKDTLVSQ-LSRGKQAFTQQIEELKRQLEEE-----IKAKS 1331
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
L S + + L+E ++ + + SK S E+ Q + + E+
Sbjct: 1332 ALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANS-EVAQWRTKYETDAIQRTEEL 1390
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ-------------------LTE 364
KKKL ++ + E ++ N L+KT KQ LQ L +
Sbjct: 1391 EEAKKKLAQRLQDAEEHVEAVNAKCASLEKT--KQRLQNEVEDLMIDVERTNAACAALDK 1448
Query: 365 IQTHYDEV----QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEE 420
Q ++D++ +++ + T + +Q+ +SL+ E+ +I+ YE++L +++++ +
Sbjct: 1449 KQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKN 1508
Query: 421 SQTRVNELTVINVN-------LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
Q +++LT L K ++EQE + + A +E L + + R+Q E
Sbjct: 1509 LQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLE 1568
Query: 474 LKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
L + + E+ +I+ +K++ V+++ L+ E + R+ K+E +
Sbjct: 1569 LNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLD-AEIRSRNDAIRLKKKMEGDLN 1627
Query: 533 DMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKR 592
+ME++L+ R AE ++ R + LK+ + ++ ++ L++ L ++ ++ +
Sbjct: 1628 EMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA 1687
Query: 593 QLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTSTVPGSQVY 651
++ E +Q+ + ++EL A +R + + N SLI K + S + G
Sbjct: 1688 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMED 1747
Query: 652 LVQESR 657
++QE+R
Sbjct: 1748 IIQEAR 1753
Score = 85.8 bits (203), Expect = 4e-16
Identities = 60/302 (19%), Positives = 140/302 (46%), Gaps = 6/302 (1%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K ++++ +K +L + + E++ ++ + + Q
Sbjct: 835 KLYFKIKPLLKSAET-EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL 893
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++Q+ + + +Q ++ K +E + +E R + IN L++ K K+E E +
Sbjct: 894 QVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 953
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNI-S 506
+ D D++ L ++ + ++K+ E + E I K+ KK+L E + +
Sbjct: 954 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1013
Query: 507 VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQC 566
++ EE + N + K KLE ++ D+E L++EK+ + + RK E LK
Sbjct: 1014 LQAEEDKVNTLTKAK---IKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQEST 1070
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
+ + + L + L+K ++S + ++ +++ + Q +++ Q +E E+ +
Sbjct: 1071 MDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAER 1130
Query: 627 SN 628
++
Sbjct: 1131 AS 1132
Score = 73.7 bits (173), Expect = 2e-12
Identities = 81/356 (22%), Positives = 166/356 (46%), Gaps = 28/356 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D+ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 977 NKVKNLTEEMAGLDETIAKLTKE--KKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQ 1034
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + + L
Sbjct: 1035 VDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGL 1094
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++E+ EQAL ++ ++++ +E Q R+ EL +S+AK E++ + ++ +
Sbjct: 1095 QSKIED-----EQALGMQ--LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL 1147
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A Q E+ E ++ R + + +L+ E ++R + +
Sbjct: 1148 EEISERLEEAGGA-TSAQIEMNKKREAEFQKMRR----DLEEATLQHEATAATLRKKHAD 1202
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI--------KILRKKERQLK 560
+ A +G +R+ KLE +M++E+D + + ET+ K+ R E QL
Sbjct: 1203 SVAELGEQIDNLQRVKQKLEKEKSEMKMEID-DLASNMETVSKAKGNLEKMCRALEDQLS 1261
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
E+ + EE Q+ I+ L + + Y RQL E++ + Q + F +++E
Sbjct: 1262 EIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIE 1317
Score = 72.9 bits (171), Expect = 3e-12
Identities = 65/316 (20%), Positives = 158/316 (50%), Gaps = 12/316 (3%)
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQY 383
IK K+Q++ E++ ++ I+ + T KK+ L + +E++ D+++ L +
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKI 442
+ ++++LT E+ + + + K+++++ ++++ + E +N L+ +K K+
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN-TLTKAKIKL 1031
Query: 443 EQELAIVAADYDEITKELRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
EQ++ + ++ K++R+ ER +R ++ +LK E + + +++ K E E
Sbjct: 1032 EQQVDDLEGSLEQ-EKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFE 1090
Query: 502 VKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKE 561
+ + ++E+ +A + K+ I +L+ARI+++E E++ E+ A+ K R+L+E
Sbjct: 1091 MSGLQSKIEDEQALGMQLQKK-IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
+ + EE S + +K + +R L E + + +R+ + A+
Sbjct: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK-----KHADSV 1204
Query: 622 ADVAESNLSLIRAKHR 637
A++ E +L R K +
Sbjct: 1205 AELGEQIDNLQRVKQK 1220
Score = 72.1 bits (169), Expect = 6e-12
Identities = 89/504 (17%), Positives = 209/504 (41%), Gaps = 32/504 (6%)
Query: 147 QEIEKELDLYEKEVN-LGSELRQKAA--MYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
Q+++++L E E++ L S++ + A M K K + Q +EE ++ ER +
Sbjct: 1078 QQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKEL-QARIEELEEEIEAERASRAKA 1136
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
+ R+ ++R+ +S+ L E+ S + + + ++
Sbjct: 1137 EKQRSDLSRELEEISER-----LEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEA 1191
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+ + + + EL E + + + + S+ +EI+ L A +E +K K +
Sbjct: 1192 TAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEM-KMEIDDL-ASNMETVSKAKGNL 1249
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++ + L+ Q++E++ + + Q+ I + Q +QT E RQL
Sbjct: 1250 EKMCRALEDQLSEIKTKEE-------EQQRLINDLTAQRARLQTESGEYSRQLDEKDTLV 1302
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES-------QTRVNELTVINVNLS 436
R Q+ T ++EE++ E+ ++ K ++ + S + + E L
Sbjct: 1303 SQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQ 1362
Query: 437 SSKAKIEQELAIVAADYD-EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ +K E+A Y+ + + +E +++ L+ EH+ + +E K
Sbjct: 1363 RAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK 1422
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGK------RIISKLEARIKDMELELDEEKRRHAETI 549
+ L+ EV+++ + +E A K +I+++ + + ++ EL+ ++
Sbjct: 1423 QRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLS 1482
Query: 550 KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
L K + +E + Q E ++ LQ + +++++ +++ E + + +Q
Sbjct: 1483 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKS 1542
Query: 610 RFQRELEAAEDRADVAESNLSLIR 633
Q LE AE + E + I+
Sbjct: 1543 ELQAALEEAEASLEHEEGKILRIQ 1566
Score = 69.3 bits (162), Expect = 4e-11
Identities = 79/347 (22%), Positives = 154/347 (44%), Gaps = 37/347 (10%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +I+++ R E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 918 QLEAKIKEVTERA-EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 976
Query: 357 KQSLQLTEIQTHYDE-----------VQRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE +Q Q TLD + ++ +LT +V+
Sbjct: 977 NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVD 1036
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +++ +E+ + + + +++ + K +++++L +++
Sbjct: 1037 DLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLK--KKEFEMSGL 1094
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHE--EQERI--VKIEAVKKSLEIEVKNISVRL 509
+ +I DE + Q+ EL+ +E L E E ER K E + L E++ IS RL
Sbjct: 1095 QSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL 1154
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 1155 EEA-GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH---ADSVAELGEQ 1210
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
N+ ++ LEK ++ + LA ++ + + R LE
Sbjct: 1211 IDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALE 1257
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 239 bits (585), Expect = 2e-62
Identities = 132/388 (34%), Positives = 225/388 (57%), Gaps = 12/388 (3%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
++RI EL + + ++ E E ++Q + Q ++E Q ++AE
Sbjct: 560 ILRIQLELTQVKSEIDRKIAEKDEEIEQLK---------RNYQRTVETMQ---SALDAEV 607
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ ++E R+KKK++ + E+E+ L AN+ + K ++ QL + Q H D+ R +
Sbjct: 608 RSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 667
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+Q + +RR L EVEE+R EQ R ++ EQ+ +S RV L N +L
Sbjct: 668 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 727
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+K K+E +L + ++ ++ +++ R A+E+ ++ T+ E L +EQ+ +E +KK+
Sbjct: 728 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 787
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
LE VK++ RL+E E A+ GGK+ I KLE RI+++E EL+ E++++ E++K LRK ER
Sbjct: 788 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYER 847
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
++KE+ Q EED+KN+ LQD ++K KV YKRQ E + + +T+ R+ Q ELE
Sbjct: 848 RVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEE 907
Query: 618 AEDRADVAESNLSLIRAKHRTFVTTSTV 645
AE+RAD+AES ++ +RAK R F ++ V
Sbjct: 908 AEERADIAESQVNKLRAKTRDFTSSRMV 935
Score = 98.7 bits (235), Expect = 6e-20
Identities = 92/424 (21%), Positives = 187/424 (44%), Gaps = 19/424 (4%)
Query: 216 NLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQ 275
N +KN LA AL S+ + CD + E + + + + N+E+ Y
Sbjct: 325 NKAKNALAHALQSSR--HDCD--LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD 380
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQIT 335
+ E +++ L DS +Q +E +NA+ E + K++LQ ++
Sbjct: 381 AIQRTEELEEAKKKLAQRLQDSEEQ----VEAVNAKCASLE--------KTKQRLQGEVE 428
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L + ++ AN L K + L E +T +E Q +L+ +L + + L
Sbjct: 429 DLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKN 488
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
EE E R +++EQ+ + ++ E L S+ +IE E A + +E
Sbjct: 489 AYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEE 548
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
L + + R+Q EL + + E+ +IE +K++ + V+ + L + E
Sbjct: 549 AEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL-DAEV 607
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
+ R+ K+E + ++E++L R+ AET+K LR + QLK+ + ++ +
Sbjct: 608 RSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 667
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIR 633
L++ L ++ ++ + ++ E +Q+ + ++EL + +R + + N SLI
Sbjct: 668 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 727
Query: 634 AKHR 637
K +
Sbjct: 728 TKKK 731
Score = 80.6 bits (190), Expect = 2e-14
Identities = 87/444 (19%), Positives = 192/444 (43%), Gaps = 19/444 (4%)
Query: 193 VQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVR 250
V++E+ FQ + L + + A+ +K S +R E ++E R+
Sbjct: 96 VEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE--RLE 153
Query: 251 ETSPTTCV-VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
E T + +N + A +L +L+E Q + + + K+ + + +L
Sbjct: 154 EAGGVTSTQIELNKKREA---EFLKLRRDLEEATLQHEAMVATL----RKKHADSVAELG 206
Query: 310 ARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
++ + ++K ++ + K + +++I +L S++ +K+ +L+K + QL+E +
Sbjct: 207 EQIDNLQ-RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKN 265
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
+E+QR L Q Q L+ ++EE Q R K++ QQ EE + ++ E
Sbjct: 266 EEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 325
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL-KHTVEHLHEEQERI 488
L+ + + ++ Y+E + + +E+ + ++ + +R
Sbjct: 326 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 385
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
++E KK L +++ ++E V A ++ +L+ ++D+ ++++ A
Sbjct: 386 EELEEAKKKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQGEVEDLMVDVERANSLAAAL 444
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSL-EKTSQKVSIYKRQLAEQEGMSQQSVTR 607
K R ++ L E +CEE Q L+ SL E S ++K + A +E + Q +
Sbjct: 445 DKKQRNFDKVLAEWKTKCEESQAE---LEASLKESRSLSTELFKLKNAYEEALDQLETVK 501
Query: 608 VRRFQRELEAAEDRADVAESNLSL 631
E E A+ +AE+ ++
Sbjct: 502 RENKNLEQEIADLTEQIAENGKTI 525
Score = 65.3 bits (152), Expect = 7e-10
Identities = 72/315 (22%), Positives = 140/315 (44%), Gaps = 22/315 (6%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
++AE + + + K KL+ Q+ +LE SL+ K +DL++ +K L Q ++
Sbjct: 12 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 71
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ Q LD+ R++ E +++ E + +++ +E Q R+ EL
Sbjct: 72 ENDKQ-QLDE------RLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI 124
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIA-DERYQRVQTELKHTVEHL---HEEQERI 488
+++AK E++ + A + +E+++ L A +++ K E L + +E
Sbjct: 125 EAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEAT 184
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDE-------E 541
++ EA+ +L + + L E N +R+ KLE + +LE+D+
Sbjct: 185 LQHEAMVATLRKKHADSVAELGEQIDNL----QRVKQKLEKEKSEFKLEIDDLSSSMESV 240
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
+ A KI R E QL E + EE Q+++S L + + RQL E+E +
Sbjct: 241 SKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIV 300
Query: 602 QQSVTRVRRFQRELE 616
Q + F ++ E
Sbjct: 301 SQLSRSKQAFTQQTE 315
Score = 45.2 bits (102), Expect = 7e-04
Identities = 41/227 (18%), Positives = 103/227 (45%), Gaps = 7/227 (3%)
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQ 468
+ K +EQQ E+ ++ + + + V+L +K K+E +L + ++ + + DER +
Sbjct: 24 KTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLK 83
Query: 469 RVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK--RIISK 526
+ E + +EQ ++ + K L+ ++ + EE+EA K + S
Sbjct: 84 KKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELE---EEIEAERATRAKTEKQRSD 140
Query: 527 LEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQ 585
++++ L+E + I++ +K+E + ++ EE ++ +++ +K +
Sbjct: 141 YARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHAD 200
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQREL-EAAEDRADVAESNLSL 631
V+ Q+ + + Q+ F+ E+ + + V++S +L
Sbjct: 201 SVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 247
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 239 bits (585), Expect = 2e-62
Identities = 122/342 (35%), Positives = 206/342 (60%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
D K+ I I + ++AE + +++ R+KKK++ + E+E+ L+ AN+ + +
Sbjct: 1588 DQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1647
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ L + Q H D+ R + +Q + +RR L E+EE+R EQ R ++ E
Sbjct: 1648 RNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1707
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ ++ RV L N +L ++K K+E +++ + + ++I +E R A+E+ ++ T+
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAA 1767
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK+LE VK++ RL+E E A+ GGK+ I KLEAR++++E
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE 1827
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
E++ E++R+ E +K LRK ER++KE+ Q EED+KNI LQD ++K KV YKRQ
Sbjct: 1828 GEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1887
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E S ++++ RR Q ELE AE+RAD+AES ++ +R K R
Sbjct: 1888 EAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
Score = 89.4 bits (212), Expect = 4e-17
Identities = 111/546 (20%), Positives = 239/546 (43%), Gaps = 46/546 (8%)
Query: 147 QEIEKELDLYEKEVN-LGSELR--QKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
Q++EKE + E++ L S + KA K +A+ L E + + +R+ D
Sbjct: 1219 QKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIN-DL 1277
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
A R + + S+ + K + S+ ++ T+ I E R E ++ +
Sbjct: 1278 TAQRARLQTESGEYSRQLDEKDTLVSQ-LSRGKQAFTQQIEELKRQLEEE-----IKAKS 1331
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
L S + + L+E ++ + + SK S E+ Q + + E+
Sbjct: 1332 ALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANS-EVAQWRTKYETDAIQRTEEL 1390
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ-------------------LTE 364
KKKL ++ + E ++ N L+KT KQ LQ L +
Sbjct: 1391 EEAKKKLAQRLQDAEEHVEAVNAKCASLEKT--KQRLQNEVEDLMIDVERTNAACAALDK 1448
Query: 365 IQTHYDEV----QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEE 420
Q ++D++ +++ + T + +Q+ +SL+ E+ +I+ YE++L +++++ +
Sbjct: 1449 KQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKN 1508
Query: 421 SQTRVNELTVINVN-------LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
Q +++LT L K ++EQE + + A +E L + + R+Q E
Sbjct: 1509 LQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLE 1568
Query: 474 LKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
L + + E+ +I+ +K++ V+++ L+ E + R+ K+E +
Sbjct: 1569 LNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLD-AEIRSRNDAIRLKKKMEGDLN 1627
Query: 533 DMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKR 592
+ME++L+ R AE ++ R + LK+ + ++ ++ L++ L ++ ++ +
Sbjct: 1628 EMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA 1687
Query: 593 QLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTSTVPGSQVY 651
++ E +Q+ + ++EL A +R + + N SLI K + S + G
Sbjct: 1688 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMED 1747
Query: 652 LVQESR 657
++QE+R
Sbjct: 1748 IIQEAR 1753
Score = 86.2 bits (204), Expect = 3e-16
Identities = 60/302 (19%), Positives = 140/302 (46%), Gaps = 6/302 (1%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K ++++ +K +L + + E++ ++ + + Q
Sbjct: 835 KLYFKIKPLLKSAET-EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL 893
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++Q+ + + +Q ++ K +E + +E R + IN L++ K K+E E +
Sbjct: 894 QVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 953
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNI-S 506
+ D D++ L ++ + ++K+ E + E I K+ KK+L E + +
Sbjct: 954 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1013
Query: 507 VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQC 566
++ EE + N + K KLE ++ D+E L++EK+ + + RK E LK
Sbjct: 1014 LQAEEDKVNTLTKAK---IKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESA 1070
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
+ + + L + L+K ++S + ++ +++ + Q +++ Q +E E+ +
Sbjct: 1071 MDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAER 1130
Query: 627 SN 628
++
Sbjct: 1131 AS 1132
Score = 73.7 bits (173), Expect = 2e-12
Identities = 81/356 (22%), Positives = 166/356 (46%), Gaps = 28/356 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D+ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 977 NKVKNLTEEMAGLDETIAKLTKE--KKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQ 1034
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + + L
Sbjct: 1035 VDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGL 1094
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++E+ EQAL ++ ++++ +E Q R+ EL +S+AK E++ + ++ +
Sbjct: 1095 QSKIED-----EQALGMQ--LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL 1147
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A Q E+ E ++ R + + +L+ E ++R + +
Sbjct: 1148 EEISERLEEAGGA-TSAQIEMNKKREAEFQKMRR----DLEEATLQHEATAATLRKKHAD 1202
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI--------KILRKKERQLK 560
+ A +G +R+ KLE +M++E+D + + ET+ K+ R E QL
Sbjct: 1203 SVAELGEQIDNLQRVKQKLEKEKSEMKMEID-DLASNMETVSKAKGNLEKMCRALEDQLS 1261
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
E+ + EE Q+ I+ L + + Y RQL E++ + Q + F +++E
Sbjct: 1262 EIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIE 1317
Score = 72.9 bits (171), Expect = 3e-12
Identities = 65/316 (20%), Positives = 158/316 (50%), Gaps = 12/316 (3%)
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQY 383
IK K+Q++ E++ ++ I+ + T KK+ L + +E++ D+++ L +
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKI 442
+ ++++LT E+ + + + K+++++ ++++ + E +N L+ +K K+
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN-TLTKAKIKL 1031
Query: 443 EQELAIVAADYDEITKELRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
EQ++ + ++ K++R+ ER +R ++ +LK E + + +++ K E E
Sbjct: 1032 EQQVDDLEGSLEQ-EKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFE 1090
Query: 502 VKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKE 561
+ + ++E+ +A + K+ I +L+ARI+++E E++ E+ A+ K R+L+E
Sbjct: 1091 MSGLQSKIEDEQALGMQLQKK-IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
+ + EE S + +K + +R L E + + +R+ + A+
Sbjct: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK-----KHADSV 1204
Query: 622 ADVAESNLSLIRAKHR 637
A++ E +L R K +
Sbjct: 1205 AELGEQIDNLQRVKQK 1220
Score = 72.9 bits (171), Expect = 3e-12
Identities = 65/350 (18%), Positives = 162/350 (46%), Gaps = 11/350 (3%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L++ K+ E+ L +++ E E L ++ + K+LQ +I ELE ++ + +K
Sbjct: 1080 LDEKLKKKEFEMSGLQSKI-EDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQ-ALRVKR 412
S +L EI +E ++ + Q + ++EE +E A +++
Sbjct: 1139 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1198
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQT 472
E +++ L + L K++++ E+ +A++ + ++K ++ + ++
Sbjct: 1199 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALED 1258
Query: 473 ELKHTVEHLHEEQERIVK-IEAVKKSLEIEVKNISVRLEEVEA--NAIVGGKRIISKLEA 529
+L ++ EEQ+R++ + A + L+ E S +L+E + + + GK+ ++
Sbjct: 1259 QLSE-IKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQ--- 1314
Query: 530 RIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
+I++++ +L+EE + + L+ + Q EE+Q+ + LQ ++ K + +V+
Sbjct: 1315 QIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQ 1374
Query: 590 YKRQLAEQEGMSQQSVTRV-RRFQRELEAAEDRADVAESN-LSLIRAKHR 637
++ + + + ++ + L+ AE+ + + SL + K R
Sbjct: 1375 WRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQR 1424
Score = 68.5 bits (160), Expect = 7e-11
Identities = 79/347 (22%), Positives = 154/347 (44%), Gaps = 37/347 (10%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +I+++ R E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 918 QLEAKIKEVTERA-EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 976
Query: 357 KQSLQLTEIQTHYDE-----------VQRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE +Q Q TLD + ++ +LT +V+
Sbjct: 977 NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVD 1036
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +++ +E+ + + + +++ + K +++++L +++
Sbjct: 1037 DLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLK--KKEFEMSGL 1094
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHE--EQERI--VKIEAVKKSLEIEVKNISVRL 509
+ +I DE + Q+ EL+ +E L E E ER K E + L E++ IS RL
Sbjct: 1095 QSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERL 1154
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 1155 EEA-GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKH---ADSVAELGEQ 1210
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
N+ ++ LEK ++ + LA ++ + + R LE
Sbjct: 1211 IDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALE 1257
Score = 63.7 bits (148), Expect = 2e-09
Identities = 58/329 (17%), Positives = 156/329 (47%), Gaps = 12/329 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
Q+++L+ +++Q + + + K + +++ Q +A +E + + E ++KKK + +
Sbjct: 1034 QVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDE--KLKKK-EFE 1090
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
++ L+ ++ + LQK IK+ ++ E++ + + Q R ++ +
Sbjct: 1091 MSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI 1150
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+ +EE G + + + E ++++ + + E T+ + ++ A + ++ A A+
Sbjct: 1151 SERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQH---EATAATLRKKHADSVAEL 1207
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK----IEAVKKSLEIEVKNISVRL 509
E L+ ++ ++ ++E+K ++ L E + K +E + ++LE ++ I +
Sbjct: 1208 GEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTK- 1266
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE + I ++L+ + +LDE+ ++ + + +Q++E+ Q EE+
Sbjct: 1267 EEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEE 1326
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
K S L +L+ + + + Q E++
Sbjct: 1327 IKAKSALAHALQSSRHDCDLLREQYEEEQ 1355
Score = 61.7 bits (143), Expect = 8e-09
Identities = 88/438 (20%), Positives = 181/438 (41%), Gaps = 31/438 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVN---LGSELRQKAAMYRGKSAKAI--AQTLLEESRRNVQNE 196
KKR E +K DL E + + LR+K A + + I Q + ++ +
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEM 1228
Query: 197 RMYKPDFQASRTLVNRDYTNLSK--NVLAKALMESKAMNSCDSRVTESITETVRVRETSP 254
+M D ++ V++ NL K L L E K R+ +T +T
Sbjct: 1229 KMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTES 1288
Query: 255 TTCVVRIN------TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQL 308
+++ ++L ++ Q+ ELK +++ ++ + Q+S L
Sbjct: 1289 GEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEE--EIKAKSALAHALQSSRHDCDL 1346
Query: 309 NARVVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQLTEIQ 366
E E + K+E+ R K ++ + + D +T +L++ KK + +L + +
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQDAE 1405
Query: 367 THYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN 426
H + V + Q ++ L +VE + +R+ ++ E + +
Sbjct: 1406 EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCE 1465
Query: 427 ELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
E T + S +++ + EL + Y+E +L + +Q E+ E + E
Sbjct: 1466 E-THAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGG 1524
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEAN-AIVGGK---------RIISKLEARIKDME 535
+RI ++E +KK +E E + LEE EA+ GK ++ S+++ +I + +
Sbjct: 1525 KRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1584
Query: 536 LELDEEKRRHAETIKILR 553
E+D+ KR H ++ ++
Sbjct: 1585 EEIDQMKRNHIRIVESMQ 1602
>BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein.
Length = 1006
Score = 238 bits (583), Expect = 4e-62
Identities = 156/497 (31%), Positives = 261/497 (52%), Gaps = 28/497 (5%)
Query: 142 QKKRMQEIEKELDLYEKEVN-LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
++++ +E+++EL+ ++E LG+EL + + G A L+ +N+Q E
Sbjct: 528 RRRQEEEMQRELEAAQRESRGLGTELFR---LRHGHEEALEALETLKRENKNLQEEIS-- 582
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
D +L + L K KA+ S + ++ E E T +R
Sbjct: 583 -DLTDQVSLSGKSIQELEKT--------KKALEGEKSEIQAALEEAEGALELEETK-TLR 632
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
I EL + +L E E + Q ++E Q + ++AET+ +
Sbjct: 633 IQLELSQVKAEVDRKLAEKDEECANLR---------RNHQRAVESLQAS---LDAETRAR 680
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+E R+KKK++ + +LEL L A + + Q + QL E Q DE QR
Sbjct: 681 NEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELH 740
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+Q +RR L E+EE+R EQ R +R EQ+ E+ R+N L N L + K
Sbjct: 741 EQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKK 800
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+E +LA ++ + +E +E R A+E+ ++ T+ E L +EQ+ +E +KK+LE
Sbjct: 801 KLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQ 860
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
V+ + RLEE E A+ GGK+ + KLEA+++++E ELD E+++HAE +K +RK ER++K
Sbjct: 861 TVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVK 920
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
E+ Q EED+KN++ +QD ++K KV YKRQ E E + ++ + R+ Q EL+ AE+
Sbjct: 921 ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE 980
Query: 621 RADVAESNLSLIRAKHR 637
RAD+AE+ + +RA+ R
Sbjct: 981 RADMAETQANKLRARTR 997
Score = 92.3 bits (219), Expect = 5e-18
Identities = 82/373 (21%), Positives = 170/373 (45%), Gaps = 18/373 (4%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ ++ +++ V A K S + + K +LQ + ++ L L+ A L K
Sbjct: 458 LEEAKKKLALRLQEAEEGVEAANAKCSS-LEKAKLRLQTESEDVTLELERATSAAAALDK 516
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L E + +E+QR+L+ AQR + L E+ +R +E+AL +
Sbjct: 517 KQRHLERALEERRRQEEEMQRELEA-------AQRESRGLGTELFRLRHGHEEALEALET 569
Query: 414 VEQQYEESQTRVNELT-VINVN------LSSSKAKIEQELAIVAADYDEITKELRIADER 466
++++ + Q +++LT ++++ L +K +E E + + A +E L + + +
Sbjct: 570 LKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETK 629
Query: 467 YQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
R+Q EL + + E+ + ++++ + V+++ L + E A R+
Sbjct: 630 TLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASL-DAETRARNEALRLKK 688
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K+E + D+EL+L R+ E R + QLKE +E+Q+ + L + + +
Sbjct: 689 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALER 748
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTST 644
+ S+ +L E +Q R ++EL A +R ++ S N L+ K + +
Sbjct: 749 RASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQ 808
Query: 645 VPGSQVYLVQESR 657
+ G QE R
Sbjct: 809 LSGEVEEAAQERR 821
Score = 75.8 bits (178), Expect = 5e-13
Identities = 63/293 (21%), Positives = 146/293 (49%), Gaps = 8/293 (2%)
Query: 346 KTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+ N DL +K + TE++ D+++ L + + ++++LT E+ + +
Sbjct: 3 EVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDESVA 62
Query: 406 QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
+ + K+++++ ++++ + L+ +K ++EQ++ + ++ K+LR+ E
Sbjct: 63 RLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQ-EKKLRMDTE 121
Query: 466 RYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
R +R ++ +LK T E + + + ++E K + E+ +S+R+E+ + K+I
Sbjct: 122 RAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKI- 180
Query: 525 SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS 584
+L+AR +++E EL+ E+ A K + R+L+E+ + EE + ++ K
Sbjct: 181 KELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKRE 240
Query: 585 QKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
++ +R+L E + +V +RR Q AE A++ E SL R + +
Sbjct: 241 AELGRLRRELEEAALRHEATVAALRRKQ-----AEGAAELGEQVDSLQRVRQK 288
Score = 61.7 bits (143), Expect = 8e-09
Identities = 80/389 (20%), Positives = 159/389 (40%), Gaps = 31/389 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D+ SV L K E Q ++AE S +T+ K +L+ Q
Sbjct: 45 NKVKNLTEEMAALDE-SVARLTKEKKALQ-EAHQQALGDLQAEEDRVSALTKAKLRLEQQ 102
Query: 334 ITELELSLDVANKTNIDLQKTIKK-----------------QSLQLTEIQTHYDEVQRQL 376
+ +LE SL+ K +D ++ +K QL E D QL
Sbjct: 103 VEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 162
Query: 377 QVTLDQYGV----AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++ + Q++I+ L EE+ E + VE+Q E+ + EL+
Sbjct: 163 SLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERL 222
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH-TVEHLHEEQERIVKI 491
+ A + A+ + +EL A R++ L+ E E E++ +
Sbjct: 223 EEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSL 282
Query: 492 EAVKKSLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEARIKDMELELDEEKRRH 545
+ V++ LE E + + ++++ AN A +++ E ++ + +++++E +R+
Sbjct: 283 QRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQL 342
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
A+ + + + E+ EE + IS L +Q + +RQL E+
Sbjct: 343 ADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALA 402
Query: 606 TRVRRFQRELE-AAEDRADVAESNLSLIR 633
V+ + + + E + AE+ L R
Sbjct: 403 HAVQALRHDCDLLREQHEEEAEAQAELQR 431
Score = 61.7 bits (143), Expect = 8e-09
Identities = 70/276 (25%), Positives = 125/276 (45%), Gaps = 22/276 (7%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
V++ +++ ++ + K +L++++ +L +++ + +K + QL+E + +E+
Sbjct: 279 VDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEEL 338
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
QRQL Q G Q L+ +EE Q R K Q EE + ++ E
Sbjct: 339 QRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEE----- 393
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE--QERI-V 489
SKAK A+ A +D LR E Q EL+ + + E Q R
Sbjct: 394 ----ESKAKSALAHAVQALRHD--CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKY 447
Query: 490 KIEAVKKSLEIE--VKNISVRLEEVE-----ANAIVGG-KRIISKLEARIKDMELELDEE 541
+ +A++++ E+E K +++RL+E E ANA ++ +L+ +D+ LEL+
Sbjct: 448 EADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERA 507
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
A K R ER L+E Q EE Q+ + Q
Sbjct: 508 TSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQ 543
Score = 58.0 bits (134), Expect = 1e-07
Identities = 93/455 (20%), Positives = 194/455 (42%), Gaps = 31/455 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKA--AMYRGKSAKAIAQTLLEESRRNVQNERMY 199
Q++ ++ E EL +E+ + LR +A A R K A+ A+ L E ++Q R
Sbjct: 232 QREGCRKREAELGRLRRELEEAA-LRHEATVAALRRKQAEGAAE--LGEQVDSLQRVRQ- 287
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
+ ++ + + +L+ NV ++ A C + + ++V E
Sbjct: 288 --KLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADA 345
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ L++L E KE + + L+ + +E+L R +E E+K
Sbjct: 346 STQRGRLQTESGELSRLLEEKECL-------ISQLSRGKALAAQSLEELR-RQLEEESKA 397
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY--DEVQRQLQ 377
KS + + L+ L + + +LQ+ + K + ++ + ++ Y D +QR +
Sbjct: 398 KSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEE 457
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+ + +A R+Q VE + K ++ + E+ + T L
Sbjct: 458 LEEAKKKLA-LRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDK 516
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ-ERIVKIEAVKK 496
+ +E+ L +E+ +EL A + + TEL + H HEE E + ++ K
Sbjct: 517 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTEL-FRLRHGHEEALEALETLKRENK 575
Query: 497 SLEIEVKNIS--VRLEEVEANAIVGGKRII----SKLEARIKDME--LELDEEK--RRHA 546
+L+ E+ +++ V L + K+ + S+++A +++ E LEL+E K R
Sbjct: 576 NLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQL 635
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E ++ + +R+L E +C ++N +SL+
Sbjct: 636 ELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQ 670
>AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 238 bits (583), Expect = 4e-62
Identities = 156/497 (31%), Positives = 261/497 (52%), Gaps = 28/497 (5%)
Query: 142 QKKRMQEIEKELDLYEKEVN-LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
++++ +E+++EL+ ++E LG+EL + + G A L+ +N+Q E
Sbjct: 1505 RRRQEEEMQRELEAAQRESRGLGTELFR---LRHGHEEALEALETLKRENKNLQEEIS-- 1559
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
D +L + L K KA+ S + ++ E E T +R
Sbjct: 1560 -DLTDQVSLSGKSIQELEKT--------KKALEGEKSEIQAALEEAEGALELEETK-TLR 1609
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
I EL + +L E E + Q ++E Q + ++AET+ +
Sbjct: 1610 IQLELSQVKAEVDRKLAEKDEECANLR---------RNHQRAVESLQAS---LDAETRAR 1657
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+E R+KKK++ + +LEL L A + + Q + QL E Q DE QR
Sbjct: 1658 NEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELH 1717
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+Q +RR L E+EE+R EQ R +R EQ+ E+ R+N L N L + K
Sbjct: 1718 EQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKK 1777
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+E +LA ++ + +E +E R A+E+ ++ T+ E L +EQ+ +E +KK+LE
Sbjct: 1778 KLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQ 1837
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
V+ + RLEE E A+ GGK+ + KLEA+++++E ELD E+++HAE +K +RK ER++K
Sbjct: 1838 TVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVK 1897
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
E+ Q EED+KN++ +QD ++K KV YKRQ E E + ++ + R+ Q EL+ AE+
Sbjct: 1898 ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE 1957
Query: 621 RADVAESNLSLIRAKHR 637
RAD+AE+ + +RA+ R
Sbjct: 1958 RADMAETQANKLRARTR 1974
Score = 92.3 bits (219), Expect = 5e-18
Identities = 82/373 (21%), Positives = 170/373 (45%), Gaps = 18/373 (4%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ ++ +++ V A K S + + K +LQ + ++ L L+ A L K
Sbjct: 1435 LEEAKKKLALRLQEAEEGVEAANAKCSS-LEKAKLRLQTESEDVTLELERATSAAAALDK 1493
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L E + +E+QR+L+ AQR + L E+ +R +E+AL +
Sbjct: 1494 KQRHLERALEERRRQEEEMQRELEA-------AQRESRGLGTELFRLRHGHEEALEALET 1546
Query: 414 VEQQYEESQTRVNELT-VINVN------LSSSKAKIEQELAIVAADYDEITKELRIADER 466
++++ + Q +++LT ++++ L +K +E E + + A +E L + + +
Sbjct: 1547 LKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETK 1606
Query: 467 YQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
R+Q EL + + E+ + ++++ + V+++ L + E A R+
Sbjct: 1607 TLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASL-DAETRARNEALRLKK 1665
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K+E + D+EL+L R+ E R + QLKE +E+Q+ + L + + +
Sbjct: 1666 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALER 1725
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTST 644
+ S+ +L E +Q R ++EL A +R ++ S N L+ K + +
Sbjct: 1726 RASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQ 1785
Query: 645 VPGSQVYLVQESR 657
+ G QE R
Sbjct: 1786 LSGEVEEAAQERR 1798
Score = 83.4 bits (197), Expect = 2e-15
Identities = 70/315 (22%), Positives = 158/315 (50%), Gaps = 10/315 (3%)
Query: 326 IKKKLQIQ--ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
IK K+Q++ + EL L+ + N DL +K + TE++ D+++ L +
Sbjct: 958 IKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEK 1017
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ ++++LT E+ + + + + K+++++ ++++ + L+ +K ++E
Sbjct: 1018 QATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLE 1077
Query: 444 QELAIVAADYDEITKELRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
Q++ + ++ K+LR+ ER +R ++ +LK T E + + + ++E K + E+
Sbjct: 1078 QQVEDLECSLEQ-EKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSEL 1136
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+S+R+E+ + K+I +L+AR +++E EL+ E+ A K + R+L+E+
Sbjct: 1137 SQLSLRVEDEQLLGAQMQKKI-KELQARAEELEEELEAERAARARVEKQRAEAARELEEL 1195
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
+ EE + ++ K ++ +R+L E + +V +RR Q AE A
Sbjct: 1196 SERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ-----AEGAA 1250
Query: 623 DVAESNLSLIRAKHR 637
++ E SL R + +
Sbjct: 1251 ELGEQVDSLQRVRQK 1265
Score = 61.7 bits (143), Expect = 8e-09
Identities = 80/389 (20%), Positives = 159/389 (40%), Gaps = 31/389 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D+ SV L K E Q ++AE S +T+ K +L+ Q
Sbjct: 1022 NKVKNLTEEMAALDE-SVARLTKEKKALQ-EAHQQALGDLQAEEDRVSALTKAKLRLEQQ 1079
Query: 334 ITELELSLDVANKTNIDLQKTIKK-----------------QSLQLTEIQTHYDEVQRQL 376
+ +LE SL+ K +D ++ +K QL E D QL
Sbjct: 1080 VEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 1139
Query: 377 QVTLDQYGV----AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++ + Q++I+ L EE+ E + VE+Q E+ + EL+
Sbjct: 1140 SLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERL 1199
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH-TVEHLHEEQERIVKI 491
+ A + A+ + +EL A R++ L+ E E E++ +
Sbjct: 1200 EEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSL 1259
Query: 492 EAVKKSLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEARIKDMELELDEEKRRH 545
+ V++ LE E + + ++++ AN A +++ E ++ + +++++E +R+
Sbjct: 1260 QRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQL 1319
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
A+ + + + E+ EE + IS L +Q + +RQL E+
Sbjct: 1320 ADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALA 1379
Query: 606 TRVRRFQRELE-AAEDRADVAESNLSLIR 633
V+ + + + E + AE+ L R
Sbjct: 1380 HAVQALRHDCDLLREQHEEEAEAQAELQR 1408
Score = 61.7 bits (143), Expect = 8e-09
Identities = 70/276 (25%), Positives = 125/276 (45%), Gaps = 22/276 (7%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
V++ +++ ++ + K +L++++ +L +++ + +K + QL+E + +E+
Sbjct: 1256 VDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEEL 1315
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
QRQL Q G Q L+ +EE Q R K Q EE + ++ E
Sbjct: 1316 QRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEE----- 1370
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE--QERI-V 489
SKAK A+ A +D LR E Q EL+ + + E Q R
Sbjct: 1371 ----ESKAKSALAHAVQALRHD--CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKY 1424
Query: 490 KIEAVKKSLEIE--VKNISVRLEEVE-----ANAIVGG-KRIISKLEARIKDMELELDEE 541
+ +A++++ E+E K +++RL+E E ANA ++ +L+ +D+ LEL+
Sbjct: 1425 EADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERA 1484
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
A K R ER L+E Q EE Q+ + Q
Sbjct: 1485 TSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQ 1520
Score = 58.0 bits (134), Expect = 1e-07
Identities = 93/455 (20%), Positives = 194/455 (42%), Gaps = 31/455 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKA--AMYRGKSAKAIAQTLLEESRRNVQNERMY 199
Q++ ++ E EL +E+ + LR +A A R K A+ A+ L E ++Q R
Sbjct: 1209 QREGCRKREAELGRLRRELEEAA-LRHEATVAALRRKQAEGAAE--LGEQVDSLQRVRQ- 1264
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
+ ++ + + +L+ NV ++ A C + + ++V E
Sbjct: 1265 --KLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADA 1322
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ L++L E KE + + L+ + +E+L R +E E+K
Sbjct: 1323 STQRGRLQTESGELSRLLEEKECL-------ISQLSRGKALAAQSLEELR-RQLEEESKA 1374
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY--DEVQRQLQ 377
KS + + L+ L + + +LQ+ + K + ++ + ++ Y D +QR +
Sbjct: 1375 KSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEE 1434
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+ + +A R+Q VE + K ++ + E+ + T L
Sbjct: 1435 LEEAKKKLA-LRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDK 1493
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ-ERIVKIEAVKK 496
+ +E+ L +E+ +EL A + + TEL + H HEE E + ++ K
Sbjct: 1494 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTEL-FRLRHGHEEALEALETLKRENK 1552
Query: 497 SLEIEVKNIS--VRLEEVEANAIVGGKRII----SKLEARIKDME--LELDEEK--RRHA 546
+L+ E+ +++ V L + K+ + S+++A +++ E LEL+E K R
Sbjct: 1553 NLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQL 1612
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E ++ + +R+L E +C ++N +SL+
Sbjct: 1613 ELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQ 1647
Score = 37.5 bits (83), Expect = 0.15
Identities = 49/198 (24%), Positives = 97/198 (48%), Gaps = 23/198 (11%)
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQ-TELKHTVE------HLHEEQERIVKIE 492
A+ E+ELA + A+ + L A+ + Q ++ T + T E L EQ+ + E
Sbjct: 892 AQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAE 951
Query: 493 A-----VKKSLEIE--VKNISVRLE-EVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+K +++E VK +S RLE E E NA + +R KLE +++ ++D+ K
Sbjct: 952 ERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARR--RKLEDECTELKKDIDDLKLT 1009
Query: 545 HAETIK---ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
A+ K K + L E + +E ++ + +L++ Q+ ++ Q AE++ +S
Sbjct: 1010 LAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQ-ALGDLQ-AEEDRVS 1067
Query: 602 QQSVTRVRRFQRELEAAE 619
+ ++ R ++++E E
Sbjct: 1068 ALTKAKL-RLEQQVEDLE 1084
>AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 238 bits (583), Expect = 4e-62
Identities = 156/497 (31%), Positives = 261/497 (52%), Gaps = 28/497 (5%)
Query: 142 QKKRMQEIEKELDLYEKEVN-LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
++++ +E+++EL+ ++E LG+EL + + G A L+ +N+Q E
Sbjct: 1505 RRRQEEEMQRELEAAQRESRGLGTELFR---LRHGHEEALEALETLKRENKNLQEEIS-- 1559
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
D +L + L K KA+ S + ++ E E T +R
Sbjct: 1560 -DLTDQVSLSGKSIQELEKT--------KKALEGEKSEIQAALEEAEGALELEETK-TLR 1609
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
I EL + +L E E + Q ++E Q + ++AET+ +
Sbjct: 1610 IQLELSQVKAEVDRKLAEKDEECANLR---------RNHQRAVESLQAS---LDAETRAR 1657
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+E R+KKK++ + +LEL L A + + Q + QL E Q DE QR
Sbjct: 1658 NEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELH 1717
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+Q +RR L E+EE+R EQ R +R EQ+ E+ R+N L N L + K
Sbjct: 1718 EQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKK 1777
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+E +LA ++ + +E +E R A+E+ ++ T+ E L +EQ+ +E +KK+LE
Sbjct: 1778 KLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQ 1837
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
V+ + RLEE E A+ GGK+ + KLEA+++++E ELD E+++HAE +K +RK ER++K
Sbjct: 1838 TVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVK 1897
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
E+ Q EED+KN++ +QD ++K KV YKRQ E E + ++ + R+ Q EL+ AE+
Sbjct: 1898 ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE 1957
Query: 621 RADVAESNLSLIRAKHR 637
RAD+AE+ + +RA+ R
Sbjct: 1958 RADMAETQANKLRARTR 1974
Score = 92.3 bits (219), Expect = 5e-18
Identities = 82/373 (21%), Positives = 170/373 (45%), Gaps = 18/373 (4%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ ++ +++ V A K S + + K +LQ + ++ L L+ A L K
Sbjct: 1435 LEEAKKKLALRLQEAEEGVEAANAKCSS-LEKAKLRLQTESEDVTLELERATSAAAALDK 1493
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L E + +E+QR+L+ AQR + L E+ +R +E+AL +
Sbjct: 1494 KQRHLERALEERRRQEEEMQRELEA-------AQRESRGLGTELFRLRHGHEEALEALET 1546
Query: 414 VEQQYEESQTRVNELT-VINVN------LSSSKAKIEQELAIVAADYDEITKELRIADER 466
++++ + Q +++LT ++++ L +K +E E + + A +E L + + +
Sbjct: 1547 LKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETK 1606
Query: 467 YQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
R+Q EL + + E+ + ++++ + V+++ L + E A R+
Sbjct: 1607 TLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASL-DAETRARNEALRLKK 1665
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K+E + D+EL+L R+ E R + QLKE +E+Q+ + L + + +
Sbjct: 1666 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALER 1725
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTST 644
+ S+ +L E +Q R ++EL A +R ++ S N L+ K + +
Sbjct: 1726 RASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQ 1785
Query: 645 VPGSQVYLVQESR 657
+ G QE R
Sbjct: 1786 LSGEVEEAAQERR 1798
Score = 83.4 bits (197), Expect = 2e-15
Identities = 70/315 (22%), Positives = 158/315 (50%), Gaps = 10/315 (3%)
Query: 326 IKKKLQIQ--ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
IK K+Q++ + EL L+ + N DL +K + TE++ D+++ L +
Sbjct: 958 IKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEK 1017
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ ++++LT E+ + + + + K+++++ ++++ + L+ +K ++E
Sbjct: 1018 QATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLE 1077
Query: 444 QELAIVAADYDEITKELRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
Q++ + ++ K+LR+ ER +R ++ +LK T E + + + ++E K + E+
Sbjct: 1078 QQVEDLECSLEQ-EKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSEL 1136
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+S+R+E+ + K+I +L+AR +++E EL+ E+ A K + R+L+E+
Sbjct: 1137 SQLSLRVEDEQLLGAQMQKKI-KELQARAEELEEELEAERAARARVEKQRAEAARELEEL 1195
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
+ EE + ++ K ++ +R+L E + +V +RR Q AE A
Sbjct: 1196 SERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ-----AEGAA 1250
Query: 623 DVAESNLSLIRAKHR 637
++ E SL R + +
Sbjct: 1251 ELGEQVDSLQRVRQK 1265
Score = 61.7 bits (143), Expect = 8e-09
Identities = 80/389 (20%), Positives = 159/389 (40%), Gaps = 31/389 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D+ SV L K E Q ++AE S +T+ K +L+ Q
Sbjct: 1022 NKVKNLTEEMAALDE-SVARLTKEKKALQ-EAHQQALGDLQAEEDRVSALTKAKLRLEQQ 1079
Query: 334 ITELELSLDVANKTNIDLQKTIKK-----------------QSLQLTEIQTHYDEVQRQL 376
+ +LE SL+ K +D ++ +K QL E D QL
Sbjct: 1080 VEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 1139
Query: 377 QVTLDQYGV----AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++ + Q++I+ L EE+ E + VE+Q E+ + EL+
Sbjct: 1140 SLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERL 1199
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH-TVEHLHEEQERIVKI 491
+ A + A+ + +EL A R++ L+ E E E++ +
Sbjct: 1200 EEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSL 1259
Query: 492 EAVKKSLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEARIKDMELELDEEKRRH 545
+ V++ LE E + + ++++ AN A +++ E ++ + +++++E +R+
Sbjct: 1260 QRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQL 1319
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
A+ + + + E+ EE + IS L +Q + +RQL E+
Sbjct: 1320 ADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALA 1379
Query: 606 TRVRRFQRELE-AAEDRADVAESNLSLIR 633
V+ + + + E + AE+ L R
Sbjct: 1380 HAVQALRHDCDLLREQHEEEAEAQAELQR 1408
Score = 61.7 bits (143), Expect = 8e-09
Identities = 70/276 (25%), Positives = 125/276 (45%), Gaps = 22/276 (7%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
V++ +++ ++ + K +L++++ +L +++ + +K + QL+E + +E+
Sbjct: 1256 VDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEEL 1315
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
QRQL Q G Q L+ +EE Q R K Q EE + ++ E
Sbjct: 1316 QRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEE----- 1370
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE--QERI-V 489
SKAK A+ A +D LR E Q EL+ + + E Q R
Sbjct: 1371 ----ESKAKSALAHAVQALRHD--CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKY 1424
Query: 490 KIEAVKKSLEIE--VKNISVRLEEVE-----ANAIVGG-KRIISKLEARIKDMELELDEE 541
+ +A++++ E+E K +++RL+E E ANA ++ +L+ +D+ LEL+
Sbjct: 1425 EADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERA 1484
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
A K R ER L+E Q EE Q+ + Q
Sbjct: 1485 TSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQ 1520
Score = 58.0 bits (134), Expect = 1e-07
Identities = 93/455 (20%), Positives = 194/455 (42%), Gaps = 31/455 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKA--AMYRGKSAKAIAQTLLEESRRNVQNERMY 199
Q++ ++ E EL +E+ + LR +A A R K A+ A+ L E ++Q R
Sbjct: 1209 QREGCRKREAELGRLRRELEEAA-LRHEATVAALRRKQAEGAAE--LGEQVDSLQRVRQ- 1264
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
+ ++ + + +L+ NV ++ A C + + ++V E
Sbjct: 1265 --KLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADA 1322
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ L++L E KE + + L+ + +E+L R +E E+K
Sbjct: 1323 STQRGRLQTESGELSRLLEEKECL-------ISQLSRGKALAAQSLEELR-RQLEEESKA 1374
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY--DEVQRQLQ 377
KS + + L+ L + + +LQ+ + K + ++ + ++ Y D +QR +
Sbjct: 1375 KSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEE 1434
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+ + +A R+Q VE + K ++ + E+ + T L
Sbjct: 1435 LEEAKKKLA-LRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDK 1493
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ-ERIVKIEAVKK 496
+ +E+ L +E+ +EL A + + TEL + H HEE E + ++ K
Sbjct: 1494 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTEL-FRLRHGHEEALEALETLKRENK 1552
Query: 497 SLEIEVKNIS--VRLEEVEANAIVGGKRII----SKLEARIKDME--LELDEEK--RRHA 546
+L+ E+ +++ V L + K+ + S+++A +++ E LEL+E K R
Sbjct: 1553 NLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQL 1612
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E ++ + +R+L E +C ++N +SL+
Sbjct: 1613 ELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQ 1647
Score = 37.5 bits (83), Expect = 0.15
Identities = 49/198 (24%), Positives = 97/198 (48%), Gaps = 23/198 (11%)
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQ-TELKHTVE------HLHEEQERIVKIE 492
A+ E+ELA + A+ + L A+ + Q ++ T + T E L EQ+ + E
Sbjct: 892 AQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAE 951
Query: 493 A-----VKKSLEIE--VKNISVRLE-EVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+K +++E VK +S RLE E E NA + +R KLE +++ ++D+ K
Sbjct: 952 ERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARR--RKLEDECTELKKDIDDLKLT 1009
Query: 545 HAETIK---ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
A+ K K + L E + +E ++ + +L++ Q+ ++ Q AE++ +S
Sbjct: 1010 LAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQ-ALGDLQ-AEEDRVS 1067
Query: 602 QQSVTRVRRFQRELEAAE 619
+ ++ R ++++E E
Sbjct: 1068 ALTKAKL-RLEQQVEDLE 1084
>AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein.
Length = 2010
Score = 238 bits (583), Expect = 4e-62
Identities = 156/497 (31%), Positives = 261/497 (52%), Gaps = 28/497 (5%)
Query: 142 QKKRMQEIEKELDLYEKEVN-LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
++++ +E+++EL+ ++E LG+EL + + G A L+ +N+Q E
Sbjct: 1532 RRRQEEEMQRELEAAQRESRGLGTELFR---LRHGHEEALEALETLKRENKNLQEEIS-- 1586
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
D +L + L K KA+ S + ++ E E T +R
Sbjct: 1587 -DLTDQVSLSGKSIQELEKT--------KKALEGEKSEIQAALEEAEGALELEETK-TLR 1636
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
I EL + +L E E + Q ++E Q + ++AET+ +
Sbjct: 1637 IQLELSQVKAEVDRKLAEKDEECANLR---------RNHQRAVESLQAS---LDAETRAR 1684
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+E R+KKK++ + +LEL L A + + Q + QL E Q DE QR
Sbjct: 1685 NEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELH 1744
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+Q +RR L E+EE+R EQ R +R EQ+ E+ R+N L N L + K
Sbjct: 1745 EQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKK 1804
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+E +LA ++ + +E +E R A+E+ ++ T+ E L +EQ+ +E +KK+LE
Sbjct: 1805 KLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQ 1864
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
V+ + RLEE E A+ GGK+ + KLEA+++++E ELD E+++HAE +K +RK ER++K
Sbjct: 1865 TVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVK 1924
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
E+ Q EED+KN++ +QD ++K KV YKRQ E E + ++ + R+ Q EL+ AE+
Sbjct: 1925 ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE 1984
Query: 621 RADVAESNLSLIRAKHR 637
RAD+AE+ + +RA+ R
Sbjct: 1985 RADMAETQANKLRARTR 2001
Score = 92.3 bits (219), Expect = 5e-18
Identities = 82/373 (21%), Positives = 170/373 (45%), Gaps = 18/373 (4%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ ++ +++ V A K S + + K +LQ + ++ L L+ A L K
Sbjct: 1462 LEEAKKKLALRLQEAEEGVEAANAKCSS-LEKAKLRLQTESEDVTLELERATSAAAALDK 1520
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L E + +E+QR+L+ AQR + L E+ +R +E+AL +
Sbjct: 1521 KQRHLERALEERRRQEEEMQRELEA-------AQRESRGLGTELFRLRHGHEEALEALET 1573
Query: 414 VEQQYEESQTRVNELT-VINVN------LSSSKAKIEQELAIVAADYDEITKELRIADER 466
++++ + Q +++LT ++++ L +K +E E + + A +E L + + +
Sbjct: 1574 LKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETK 1633
Query: 467 YQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
R+Q EL + + E+ + ++++ + V+++ L + E A R+
Sbjct: 1634 TLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASL-DAETRARNEALRLKK 1692
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K+E + D+EL+L R+ E R + QLKE +E+Q+ + L + + +
Sbjct: 1693 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALER 1752
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTST 644
+ S+ +L E +Q R ++EL A +R ++ S N L+ K + +
Sbjct: 1753 RASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQ 1812
Query: 645 VPGSQVYLVQESR 657
+ G QE R
Sbjct: 1813 LSGEVEEAAQERR 1825
Score = 83.8 bits (198), Expect = 2e-15
Identities = 70/315 (22%), Positives = 158/315 (50%), Gaps = 10/315 (3%)
Query: 326 IKKKLQIQ--ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
IK K+Q++ + EL L+ + N DL +K + TE++ D+++ L +
Sbjct: 985 IKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEK 1044
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ ++++LT E+ + + + + K+++++ ++++ + L+ +K ++E
Sbjct: 1045 QATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLE 1104
Query: 444 QELAIVAADYDEITKELRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
Q++ + ++ K+LR+ ER +R ++ +LK T E + + + ++E K + E+
Sbjct: 1105 QQVEDLECSLEQ-EKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSEL 1163
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+S+R+E+ + K+I +L+AR +++E EL+ E+ A K + R+L+E+
Sbjct: 1164 SQLSLRVEDEQLLGAQMQKKI-KELQARAEELEEELEAERAARARVEKQRAEAARELEEL 1222
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
+ EE + ++ K ++ +R+L E + +V +RR Q AE A
Sbjct: 1223 SERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ-----AEGAA 1277
Query: 623 DVAESNLSLIRAKHR 637
++ E SL R + +
Sbjct: 1278 ELGEQVDSLQRVRQK 1292
Score = 66.9 bits (156), Expect = 2e-10
Identities = 94/389 (24%), Positives = 168/389 (43%), Gaps = 50/389 (12%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
E++NA + KL+ E T +KK I +LEL+L A K + +K LTE
Sbjct: 1006 EEVNADLAARRRKLEDECTELKK----DIDDLELTLAKAEKEKQATENKVK----NLTEE 1057
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRV 425
DE +L T ++ + + Q+L G+++ + K +EQQ E+ + +
Sbjct: 1058 MAALDESVARL--TKEKKALQEAHQQAL-GDLQAEEDRVSALTKAKLRLEQQVEDLECSL 1114
Query: 426 NELTVINVNLSSSKAKIEQEL-------AIVAADYDEITKE------------LRIADE- 465
+ + ++ +K K+E +L A A D ++ ++ LR+ DE
Sbjct: 1115 EQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQ 1174
Query: 466 ----RYQRVQTELKHTVEHLHE--EQERIVKIEAVKKSLEI--EVKNISVRLEEVEANAI 517
+ Q+ EL+ E L E E ER + K+ E E++ +S RLEE A
Sbjct: 1175 LLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEA-GGAS 1233
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
G + K EA + + EL+E RH T+ LR+K+ E + E ++ ++
Sbjct: 1234 AGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ---AEGAAELGEQVDSLQRVR 1290
Query: 578 DSLEKTSQKVSIYKRQLA---EQEGMSQQSVTRV-RRFQRELEAAEDRADVAESNLSLIR 633
LEK ++ + LA E ++ S ++ R ++ +L A+ + + + L+
Sbjct: 1291 QKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADAS 1350
Query: 634 AKHRTFVTTSTVPGSQVYLVQESRALSSE 662
+ T S G L++E L S+
Sbjct: 1351 TQRGRLQTES---GELSRLLEEKECLISQ 1376
Score = 61.7 bits (143), Expect = 8e-09
Identities = 80/389 (20%), Positives = 159/389 (40%), Gaps = 31/389 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D+ SV L K E Q ++AE S +T+ K +L+ Q
Sbjct: 1049 NKVKNLTEEMAALDE-SVARLTKEKKALQ-EAHQQALGDLQAEEDRVSALTKAKLRLEQQ 1106
Query: 334 ITELELSLDVANKTNIDLQKTIKK-----------------QSLQLTEIQTHYDEVQRQL 376
+ +LE SL+ K +D ++ +K QL E D QL
Sbjct: 1107 VEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 1166
Query: 377 QVTLDQYGV----AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++ + Q++I+ L EE+ E + VE+Q E+ + EL+
Sbjct: 1167 SLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERL 1226
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH-TVEHLHEEQERIVKI 491
+ A + A+ + +EL A R++ L+ E E E++ +
Sbjct: 1227 EEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSL 1286
Query: 492 EAVKKSLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEARIKDMELELDEEKRRH 545
+ V++ LE E + + ++++ AN A +++ E ++ + +++++E +R+
Sbjct: 1287 QRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQL 1346
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
A+ + + + E+ EE + IS L +Q + +RQL E+
Sbjct: 1347 ADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALA 1406
Query: 606 TRVRRFQRELE-AAEDRADVAESNLSLIR 633
V+ + + + E + AE+ L R
Sbjct: 1407 HAVQALRHDCDLLREQHEEEAEAQAELQR 1435
Score = 61.7 bits (143), Expect = 8e-09
Identities = 70/276 (25%), Positives = 125/276 (45%), Gaps = 22/276 (7%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
V++ +++ ++ + K +L++++ +L +++ + +K + QL+E + +E+
Sbjct: 1283 VDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEEL 1342
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
QRQL Q G Q L+ +EE Q R K Q EE + ++ E
Sbjct: 1343 QRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEE----- 1397
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE--QERI-V 489
SKAK A+ A +D LR E Q EL+ + + E Q R
Sbjct: 1398 ----ESKAKSALAHAVQALRHD--CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKY 1451
Query: 490 KIEAVKKSLEIE--VKNISVRLEEVE-----ANAIVGG-KRIISKLEARIKDMELELDEE 541
+ +A++++ E+E K +++RL+E E ANA ++ +L+ +D+ LEL+
Sbjct: 1452 EADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERA 1511
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
A K R ER L+E Q EE Q+ + Q
Sbjct: 1512 TSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQ 1547
Score = 58.0 bits (134), Expect = 1e-07
Identities = 93/455 (20%), Positives = 194/455 (42%), Gaps = 31/455 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKA--AMYRGKSAKAIAQTLLEESRRNVQNERMY 199
Q++ ++ E EL +E+ + LR +A A R K A+ A+ L E ++Q R
Sbjct: 1236 QREGCRKREAELGRLRRELEEAA-LRHEATVAALRRKQAEGAAE--LGEQVDSLQRVRQ- 1291
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
+ ++ + + +L+ NV ++ A C + + ++V E
Sbjct: 1292 --KLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADA 1349
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ L++L E KE + + L+ + +E+L R +E E+K
Sbjct: 1350 STQRGRLQTESGELSRLLEEKECL-------ISQLSRGKALAAQSLEELR-RQLEEESKA 1401
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY--DEVQRQLQ 377
KS + + L+ L + + +LQ+ + K + ++ + ++ Y D +QR +
Sbjct: 1402 KSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEE 1461
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+ + +A R+Q VE + K ++ + E+ + T L
Sbjct: 1462 LEEAKKKLA-LRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDK 1520
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ-ERIVKIEAVKK 496
+ +E+ L +E+ +EL A + + TEL + H HEE E + ++ K
Sbjct: 1521 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTEL-FRLRHGHEEALEALETLKRENK 1579
Query: 497 SLEIEVKNIS--VRLEEVEANAIVGGKRII----SKLEARIKDME--LELDEEK--RRHA 546
+L+ E+ +++ V L + K+ + S+++A +++ E LEL+E K R
Sbjct: 1580 NLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQL 1639
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E ++ + +R+L E +C ++N +SL+
Sbjct: 1640 ELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQ 1674
Score = 36.3 bits (80), Expect = 0.35
Identities = 42/155 (27%), Positives = 76/155 (49%), Gaps = 23/155 (14%)
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQ-TELKHTVE------HLHEEQERIVKIE 492
A+ E+ELA + A+ + L A+ + Q ++ T + T E L EQ+ + E
Sbjct: 919 AQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAE 978
Query: 493 A-----VKKSLEIE--VKNISVRLE-EVEANAIVGGKR-----IISKLEARIKDMELEL- 538
+K +++E VK +S RLE E E NA + +R ++L+ I D+EL L
Sbjct: 979 ERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLA 1038
Query: 539 --DEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
++EK+ +K L ++ L E + + +++K
Sbjct: 1039 KAEKEKQATENKVKNLTEEMAALDESVARLTKEKK 1073
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 238 bits (582), Expect = 5e-62
Identities = 132/388 (34%), Positives = 224/388 (57%), Gaps = 12/388 (3%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
++RI EL + + ++ E E ++Q + Q ++E Q ++AE
Sbjct: 704 ILRIQLELTQVKSEIDRKIAEKDEEIEQLK---------RNYQRTVETMQ---SALDAEV 751
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ +E R+KKK++ + E+E+ L AN+ + K ++ QL + Q H D+ R +
Sbjct: 752 RRANEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 811
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+Q + +RR L EVEE+R EQ R ++ EQ+ +S RV L N +L
Sbjct: 812 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 871
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+K K+E +L + ++ ++ +++ R A+E+ ++ T+ E L +EQ+ +E +KK+
Sbjct: 872 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 931
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
LE VK++ RL+E E A+ GGK+ I KLE RI+++E EL+ E++++ E++K LRK ER
Sbjct: 932 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYER 991
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
++KE+ Q EED+KN+ LQD ++K KV YKRQ E + + +T+ R+ Q ELE
Sbjct: 992 RVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEE 1051
Query: 618 AEDRADVAESNLSLIRAKHRTFVTTSTV 645
AE+RAD+AES ++ +RAK R F ++ V
Sbjct: 1052 AEERADIAESQVNKLRAKTRDFTSSRMV 1079
Score = 97.1 bits (231), Expect = 2e-19
Identities = 91/424 (21%), Positives = 185/424 (43%), Gaps = 19/424 (4%)
Query: 216 NLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQ 275
N +KN L AL S+ + CD + E + + + + N+E+ Y
Sbjct: 469 NKAKNALGHALQSSR--HDCD--LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD 524
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQIT 335
+ E +++ L DS +Q +E +NA+ E + K++LQ ++
Sbjct: 525 AIQRTEELEEAKKKLAQRLQDSEEQ----VEAVNAKCASLE--------KTKQRLQGEVE 572
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L + ++ AN L K + L E +T +E Q +L+ +L + + L
Sbjct: 573 DLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKN 632
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
EE E R +++EQ+ + ++ E L S+ +IE E A + +E
Sbjct: 633 AYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEE 692
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
L + + R+Q EL + + E+ +IE +K++ + V+ + L + E
Sbjct: 693 AEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL-DAEV 751
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
R+ K+E + ++E++L R+ AET+K LR + QLK+ + ++ +
Sbjct: 752 RRANEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 811
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIR 633
L++ L ++ ++ + ++ E +Q+ + ++EL + +R + + N SLI
Sbjct: 812 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 871
Query: 634 AKHR 637
K +
Sbjct: 872 TKKK 875
Score = 82.2 bits (194), Expect = 5e-15
Identities = 57/271 (21%), Positives = 129/271 (47%), Gaps = 7/271 (2%)
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+K +L + + E++ +L + + Q ++Q+ + + + +Q ++ K +E
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
+ +E R + IN L++ K K+E E + + D D++ L ++ + ++K
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
+ E L E I K+ KK+L+ E ++ + E + + + SKLE +++D+E
Sbjct: 123 NLTEELSGLDETIAKLTREKKALQ-EAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLE 181
Query: 536 LELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKR 592
L++EK+ + + RK E LK E I+ E D++ L + L+K + +
Sbjct: 182 SSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQ---LDERLKKKDFEYCQLQS 238
Query: 593 QLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 239 KVEDEQTLGLQFQKKIKELQARIEELEEEIE 269
Score = 80.2 bits (189), Expect = 2e-14
Identities = 87/444 (19%), Positives = 191/444 (43%), Gaps = 19/444 (4%)
Query: 193 VQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVR 250
V++E+ FQ + L + + A+ +K S +R E ++E R+
Sbjct: 240 VEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE--RLE 297
Query: 251 ETSPTTCV-VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
E T + +N + A +L +L+E Q + + + K+ + + +L
Sbjct: 298 EAGGVTSTQIELNKKREA---EFLKLRRDLEEATLQHEAMVATL----RKKHADSVAELG 350
Query: 310 ARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
++ + ++K ++ + K + +++I +L S++ +K+ +L+K + QL+E +
Sbjct: 351 EQIDNLQ-RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKN 409
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
+E+QR L Q Q L+ ++EE Q R K++ QQ EE + ++ E
Sbjct: 410 EEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 469
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL-KHTVEHLHEEQERI 488
L + + ++ Y+E + + +E+ + ++ + +R
Sbjct: 470 KAKNALGHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 529
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
++E KK L +++ ++E V A ++ +L+ ++D+ ++++ A
Sbjct: 530 EELEEAKKKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQGEVEDLMVDVERANSLAAAL 588
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSL-EKTSQKVSIYKRQLAEQEGMSQQSVTR 607
K R ++ L E +CEE Q L+ SL E S ++K + A +E + Q +
Sbjct: 589 DKKQRNFDKVLAEWKTKCEESQAE---LEASLKESRSLSTELFKLKNAYEEALDQLETVK 645
Query: 608 VRRFQRELEAAEDRADVAESNLSL 631
E E A+ +AE+ ++
Sbjct: 646 RENKNLEQEIADLTEQIAENGKTI 669
Score = 62.1 bits (144), Expect = 6e-09
Identities = 68/340 (20%), Positives = 157/340 (46%), Gaps = 16/340 (4%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +I+++ R E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 60 QLEAKIKEVTERA-EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 118
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG-EVEEIRGNYEQALRVKRSVE 415
+ LTE + DE +L T ++ + + Q+L + EE + N + K +E
Sbjct: 119 NKVKNLTEELSGLDETIAKL--TREKKALQEAHQQALDDLQAEEDKVN--SLNKTKSKLE 174
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
QQ E+ ++ + + + V+L +K K+E +L + ++ + + DER ++ E
Sbjct: 175 QQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYC 234
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK--RIISKLEARIKD 533
+ +EQ ++ + K L+ ++ + EE+EA K + S +++
Sbjct: 235 QLQSKVEDEQTLGLQFQKKIKELQARIEELE---EEIEAERATRAKTEKQRSDYARELEE 291
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKR 592
+ L+E + I++ +K+E + ++ EE ++ +++ +K + V+
Sbjct: 292 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGE 351
Query: 593 QLAEQEGMSQQSVTRVRRFQREL-EAAEDRADVAESNLSL 631
Q+ + + Q+ F+ E+ + + V++S +L
Sbjct: 352 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 391
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 238 bits (582), Expect = 5e-62
Identities = 131/388 (33%), Positives = 225/388 (57%), Gaps = 12/388 (3%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
++RI EL + + ++ E E ++Q + Q ++E Q ++AE
Sbjct: 786 ILRIQLELTQVKSEIDRKIAEKDEEIEQLK---------RNYQRTVETMQ---SALDAEV 833
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ ++E R+KKK++ + E+E+ L AN+ + K ++ QL + Q H D+ + +
Sbjct: 834 RSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQE 893
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+Q + +RR L EVEE+R EQ R ++ EQ+ +S RV L N +L
Sbjct: 894 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 953
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+K K+E +L + ++ ++ +++ R A+E+ ++ T+ E L +EQ+ +E +KK+
Sbjct: 954 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1013
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
LE VK++ RL+E E A+ GGK+ I KLE RI+++E EL+ E++++ E++K LRK ER
Sbjct: 1014 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYER 1073
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
++KE+ Q EED+KN+ LQD ++K KV YKRQ E + + +T+ R+ Q ELE
Sbjct: 1074 RVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEE 1133
Query: 618 AEDRADVAESNLSLIRAKHRTFVTTSTV 645
AE+RAD+AES ++ +RAK R F ++ V
Sbjct: 1134 AEERADIAESQVNKLRAKTRDFTSSRMV 1161
Score = 99 bits (238), Expect = 2e-20
Identities = 92/424 (21%), Positives = 188/424 (44%), Gaps = 19/424 (4%)
Query: 216 NLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQ 275
N +KN LA AL S+ + CD + E + + + + N+E+ Y
Sbjct: 551 NKAKNALAHALQSSR--HDCD--LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD 606
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQIT 335
+ E +++ + L DS +Q +E +NA+ E + K++LQ ++
Sbjct: 607 AIQRTEELEEAQEKLAQRLQDSEEQ----VEAVNAKCASLE--------KTKQRLQGEVE 654
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L + ++ AN L K + L E +T +E Q +L+ +L + + L
Sbjct: 655 DLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKN 714
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
EE E R +++EQ+ + ++ E L S+ +IE E A + +E
Sbjct: 715 AYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEE 774
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
L + + R+Q EL + + E+ +IE +K++ + V+ + L + E
Sbjct: 775 AEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL-DAEV 833
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
+ R+ K+E + ++E++L R+ AET+K LR + QLK+ + ++ +
Sbjct: 834 RSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQE 893
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIR 633
L++ L ++ ++ + ++ E +Q+ + ++EL + +R + + N SLI
Sbjct: 894 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 953
Query: 634 AKHR 637
K +
Sbjct: 954 TKKK 957
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/298 (21%), Positives = 140/298 (46%), Gaps = 8/298 (2%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K +++ +K +L + + E++ +L + + Q
Sbjct: 59 KLFFKIKPLLKSAET-EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQL 117
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++Q+ + + + +Q ++ K +E + +E R + IN L++ K K+E E +
Sbjct: 118 QVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 177
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVR 508
+ D D++ L ++ + ++K+ E L E I K+ KK+L+ E ++
Sbjct: 178 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQ-EAHQQALD 236
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK---EVIIQ 565
+ E + + + SKLE +++D+E L++EK+ + + RK E LK E I+
Sbjct: 237 DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD 296
Query: 566 CEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
E D++ L + L+K + + ++ +++ + Q +++ Q +E E+ +
Sbjct: 297 LENDKQQ---LDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIE 351
Score = 77.4 bits (182), Expect = 2e-13
Identities = 85/444 (19%), Positives = 192/444 (43%), Gaps = 19/444 (4%)
Query: 193 VQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVR 250
V++E+ FQ + L + + A+ +K S +R E ++E R+
Sbjct: 322 VEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE--RLE 379
Query: 251 ETSPTTCV-VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
E T + +N + A +L +L+E Q + + + K+ + + +L
Sbjct: 380 EAGGVTSTQIELNKKREA---EFLKLRRDLEEATLQHEAMVATL----RKKHADSVAELG 432
Query: 310 ARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
++ + ++K ++ + K + +++I +L S++ +K+ +L+K + QL+E +
Sbjct: 433 EQIDNLQ-RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKN 491
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
+E+QR L Q Q L+ ++EE Q R K++ QQ EE + ++ E
Sbjct: 492 EEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 551
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL-KHTVEHLHEEQERI 488
L+ + + ++ Y+E + + +E+ + ++ + +R
Sbjct: 552 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 611
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
++E ++ L +++ ++E V A ++ +L+ ++D+ ++++ A
Sbjct: 612 EELEEAQEKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQGEVEDLMVDVERANSLAAAL 670
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSL-EKTSQKVSIYKRQLAEQEGMSQQSVTR 607
K R ++ L E +CEE Q L+ SL E S ++K + A +E + Q +
Sbjct: 671 DKKQRNFDKVLAEWKTKCEESQAE---LEASLKESRSLSTELFKLKNAYEEALDQLETVK 727
Query: 608 VRRFQRELEAAEDRADVAESNLSL 631
E E A+ +AE+ ++
Sbjct: 728 RENKNLEQEIADLTEQIAENGKTI 751
Score = 62.1 bits (144), Expect = 6e-09
Identities = 68/340 (20%), Positives = 157/340 (46%), Gaps = 16/340 (4%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +I+++ R E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 142 QLEAKIKEVTERA-EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 200
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG-EVEEIRGNYEQALRVKRSVE 415
+ LTE + DE +L T ++ + + Q+L + EE + N + K +E
Sbjct: 201 NKVKNLTEELSGLDETIAKL--TREKKALQEAHQQALDDLQAEEDKVN--SLNKTKSKLE 256
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
QQ E+ ++ + + + V+L +K K+E +L + ++ + + DER ++ E
Sbjct: 257 QQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYC 316
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK--RIISKLEARIKD 533
+ +EQ ++ + K L+ ++ + EE+EA K + S +++
Sbjct: 317 QLQSKVEDEQTLGLQFQKKIKELQARIEELE---EEIEAERATRAKTEKQRSDYARELEE 373
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKR 592
+ L+E + I++ +K+E + ++ EE ++ +++ +K + V+
Sbjct: 374 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGE 433
Query: 593 QLAEQEGMSQQSVTRVRRFQREL-EAAEDRADVAESNLSL 631
Q+ + + Q+ F+ E+ + + V++S +L
Sbjct: 434 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 473
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 238 bits (582), Expect = 5e-62
Identities = 122/342 (35%), Positives = 205/342 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
D K+ I IE+ + AE + +++ R+KKK++ + E+E+ L+ AN+ + +
Sbjct: 525 DQMKRNHIRIEESMQSTLNAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNY 584
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ L + Q H D+ R + +Q + +RR L E+EE+R EQ R ++ E
Sbjct: 585 QNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 644
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ ++ RV L N +L ++K K+E +++ + + ++I KE R A+E+ ++ T+
Sbjct: 645 QELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAA 704
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK+LE VK++ RL+E E A+ GGK+ I KLEA+++++E
Sbjct: 705 MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAKVRELE 764
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
E++ E++R+ E +K L K ER++KE+ Q EED+KNI LQD ++K KV YKRQ
Sbjct: 765 GEVESEQKRNVEAVKGLHKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 824
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E S ++++ RR Q ELE AE+RAD+AES ++ +R K R
Sbjct: 825 EAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 866
Score = 87.0 bits (206), Expect = 2e-16
Identities = 107/546 (19%), Positives = 236/546 (43%), Gaps = 46/546 (8%)
Query: 147 QEIEKELDLYEKEVN-LGSELR--QKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
Q++EKE + E++ L S + KA K +A+ L E + + +R+ D
Sbjct: 156 QKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIN-DL 214
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
A R + ++ S+ + K +E++ ++ T+ I E R E ++ +
Sbjct: 215 TAQRARLQQNQVEYSRQLDEKDTLETQ-LSRGKQAFTQQIEELKRQLEEE-----IKAKS 268
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
L S + + L+E ++ + + SK S E+ Q + + E+
Sbjct: 269 ALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANS-EVAQWRTKYETDAIQRTEEL 327
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ-------------------LTE 364
KKKL ++ + E ++ N L+KT KQ LQ L +
Sbjct: 328 EEAKKKLAQRLQDAEEHVEAVNAKCASLEKT--KQRLQNEVEDLMIDVERTNAACAALDK 385
Query: 365 IQTHYDEVQRQLQVTLDQYGVA----QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEE 420
QT++D++ + + ++ Q+ +SL+ E+ +I+ YE++L +++++ +
Sbjct: 386 KQTNFDKILAEWKQKCEETHAVLESFQKESRSLSTELFKIKNAYEESLDQLETLKRENKN 445
Query: 421 SQTRVNELTVINVN-------LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
Q +++LT L K ++EQE + + A +E L + + R+Q E
Sbjct: 446 LQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLE 505
Query: 474 LKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
+ + + E+ +I+ +K++ I ++ E + R+ K+E +
Sbjct: 506 VNQVKSEVDRKIAEKDEEIDQMKRN-HIRIEESMQSTLNAEIRSRNDAIRLKKKMEGDLN 564
Query: 533 DMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKR 592
+ME++L+ R AE ++ + + LK+ + ++ ++ L++ L ++ ++ +
Sbjct: 565 EMEIQLNHANRMAAEDLRNYQNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA 624
Query: 593 QLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTSTVPGSQVY 651
++ E +Q+ + ++EL A +R + + N SLI K + S + G
Sbjct: 625 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMED 684
Query: 652 LVQESR 657
+++E+R
Sbjct: 685 IIKEAR 690
Score = 65.7 bits (153), Expect = 5e-10
Identities = 83/435 (19%), Positives = 176/435 (40%), Gaps = 20/435 (4%)
Query: 143 KKRMQEIEK-ELDLYEKEVN---LGSELRQKAAMYRGKSAKAI--AQTLLEESRRNVQNE 196
KKR E +K DL E + + LR+K A + + I Q + ++ +
Sbjct: 106 KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEM 165
Query: 197 RMYKPDFQASRTLVNRDYTNLSK--NVLAKALMESKAMNSCDSRVTESIT-ETVRVRETS 253
+M D ++ V++ NL K L L E K R+ +T + R+++
Sbjct: 166 KMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQ 225
Query: 254 PTTCVV-----RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQL 308
+ T+L ++ Q+ ELK +++ ++ + Q+S L
Sbjct: 226 VEYSRQLDEKDTLETQLSRGKQAFTQQIEELKRQLEE--EIKAKSALAHALQSSRHDCDL 283
Query: 309 NARVVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQLTEIQ 366
E E + K+E+ R K ++ + + D +T +L++ KK + +L + +
Sbjct: 284 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQDAE 342
Query: 367 THYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN 426
H + V + Q ++ L +VE + + + ++ E + +
Sbjct: 343 EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQTNFDKILAEWKQKCE 402
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQE 486
E + + + EL + Y+E +L + +Q E+ E + E +
Sbjct: 403 ETHAVLESFQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGK 462
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
RI ++E +KK +E E + LEE EA+ +I+ +++ + ++ E+D +
Sbjct: 463 RIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKIL-RIQLEVNQVKSEVDRKIAEKD 521
Query: 547 ETIKILRKKERQLKE 561
E I +++ +++E
Sbjct: 522 EEIDQMKRNHIRIEE 536
Score = 58.8 bits (136), Expect = 6e-08
Identities = 56/287 (19%), Positives = 130/287 (45%), Gaps = 16/287 (5%)
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
K ++ KK + +++ L+ ++ + LQK IK E+Q +E++ +++
Sbjct: 14 KQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIK-------ELQARIEELEEEIEAE 66
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQAL-RVKRSVE---QQYEESQTRVNELTVINVNL 435
A++ L+ E+EEI E+A+ +E ++ E Q +L +
Sbjct: 67 RTSRAKAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLEEATLQH 126
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK----I 491
++ A + ++ A A+ E L+ ++ ++ ++E+K ++ L E + K +
Sbjct: 127 EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNL 186
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
E + ++LE ++ I + EE + I ++L+ + +LDE+ + +
Sbjct: 187 EKMCRALEDQLSEIKTK-EEEQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLETQLSRG 245
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
+ +Q++E+ Q EE+ K S L +L+ + + + Q E++
Sbjct: 246 KQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQ 292
Score = 57.2 bits (132), Expect = 2e-07
Identities = 55/267 (20%), Positives = 129/267 (48%), Gaps = 15/267 (5%)
Query: 338 ELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEV 397
E ++D+ N L + +KK+ +++ +Q+ ++ Q + Q RI+ L E+
Sbjct: 5 ESAMDIENDKQ-QLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEI 63
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
E R + +A +++ + ++ EE R+ E V +S++ ++ ++ A++ ++
Sbjct: 64 EAERTSRAKAEKLRSDLSRELEEISERLEEA----VGATSTQIEMNKKR---EAEFQKMR 116
Query: 458 KELRIADERYQRVQTEL-KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN- 515
++L A +++ L K + + E E+I ++ VK+ LE E + + ++++ +N
Sbjct: 117 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 176
Query: 516 -AIVGGKRIISKLEARIKDMELEL---DEEKRRHAETIKILRKKERQLK-EVIIQCEEDQ 570
+ K + K+ ++D E+ +EE++R + R + +Q + E Q +E
Sbjct: 177 ETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEKD 236
Query: 571 KNISLLQDSLEKTSQKVSIYKRQLAEQ 597
+ L + +Q++ KRQL E+
Sbjct: 237 TLETQLSRGKQAFTQQIEELKRQLEEE 263
Score = 55.6 bits (128), Expect = 5e-07
Identities = 72/460 (15%), Positives = 180/460 (39%), Gaps = 24/460 (5%)
Query: 185 LLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESIT 244
L +ES +++N++ + + + ++ A + K + +R+ E +
Sbjct: 2 LAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI-EELE 60
Query: 245 ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE 304
E + TS R E D S +L E+ E +++ + + + +K+ E
Sbjct: 61 EEIEAERTS------RAKAEKLRSDLS--RELEEISERLEEAVGATSTQI-EMNKKREAE 111
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+++ + EA + ++ ++KK + EL +D +LQ+ +K + +E
Sbjct: 112 FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-------NLQRVKQKLEKEKSE 164
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV-------KRSVEQQ 417
++ D++ ++ G ++ ++L ++ EI+ E+ R+ + ++Q
Sbjct: 165 MKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQN 224
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHT 477
E +++E + LS K Q++ + +E K Q + +
Sbjct: 225 QVEYSRQLDEKDTLETQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLL 284
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE 537
E EEQE +++ EV + E + KL R++D E
Sbjct: 285 REQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEH 344
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
++ + A K ++ + ++++++I E + L + ++ +K++ E
Sbjct: 345 VEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQTNFDKILAEWKQKCEET 404
Query: 598 EGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ + R EL ++ + + L ++ +++
Sbjct: 405 HAVLESFQKESRSLSTELFKIKNAYEESLDQLETLKRENK 444
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 238 bits (582), Expect = 5e-62
Identities = 121/342 (35%), Positives = 207/342 (60%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
D K+ I I + ++AE + +++ R+KKK++ + E+E+ L+ AN+ + +
Sbjct: 1590 DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1649
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ L + Q H D+ R + +Q + +RR L E+EE+R EQ R ++ E
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ ++ RV L N +L ++K K+E +++ + + ++I +E R A+E+ ++ T+
Sbjct: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAA 1769
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E VK++ +RL+E E A+ GGK+ I KLEAR++++E
Sbjct: 1770 MMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELE 1829
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
E++ E++R+AE +K LRK ER++KE+ Q EED+KNI LQD ++K KV YKRQ
Sbjct: 1830 GEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1889
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E S ++ + R+ Q ELE AE+RAD+AES ++ +R K R
Sbjct: 1890 EAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
Score = 84.6 bits (200), Expect = 1e-15
Identities = 77/373 (20%), Positives = 171/373 (45%), Gaps = 18/373 (4%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ + ++ V K S + + K++LQ ++ +L L ++ N L K
Sbjct: 1392 LEEAKKKLAQRLQAAEEHVEAVNAKCAS-LEKTKQRLQNEVEDLMLDVERTNAACAALDK 1450
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L E + +E +L+ + Q+ +SL E+ +I+ YE++L +
Sbjct: 1451 KQRNFDKILAEWKQKCEETHAELEAS-------QKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 414 VEQQYEESQTRVNELTVINVN-------LSSSKAKIEQELAIVAADYDEITKELRIADER 466
++++ + Q +++LT L K ++EQE + A +E L + +
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563
Query: 467 YQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
R+Q EL + + E+ +I+ +K++ V+++ L+ E + R+
Sbjct: 1564 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLD-AEIRSRNDAIRLKK 1622
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K+E + +ME++L+ R AE ++ R + LK+ I ++ ++ L++ L +
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTST 644
+ ++ + ++ E +Q+ + ++EL A +R + + N SLI K + S
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 645 VPGSQVYLVQESR 657
+ G ++QE+R
Sbjct: 1743 MQGEMEDILQEAR 1755
Score = 82.6 bits (195), Expect = 4e-15
Identities = 64/305 (20%), Positives = 143/305 (46%), Gaps = 12/305 (3%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K +++ +K +L + + E++ ++ L + Q
Sbjct: 837 KLFFKIKPLLKSAET-EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQL 895
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++Q+ + + +Q ++ K +E + +E R + IN L++ K K+E E +
Sbjct: 896 QVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 955
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNI-S 506
+ D D++ L ++ + ++K+ E + E I K+ KK+L E + +
Sbjct: 956 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1015
Query: 507 VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK---EVI 563
++ EE + N + K KLE ++ D+E L++EK+ + + RK E LK E I
Sbjct: 1016 LQAEEDKVNTLTKAK---IKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESI 1072
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
+ E +++ L + L+K ++S + ++ +++ + Q +++ Q +E E+ +
Sbjct: 1073 MDIENEKQQ---LDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129
Query: 624 VAESN 628
++
Sbjct: 1130 AERAS 1134
Score = 80.6 bits (190), Expect = 2e-14
Identities = 73/358 (20%), Positives = 178/358 (49%), Gaps = 16/358 (4%)
Query: 284 KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDV 343
K+ ++ V +L + + ++++ + +AE + IK K+Q++ E++
Sbjct: 877 KELEEKMVTLLKEKN-DLQLQVQAEAEGLADAEERCDQ---LIKTKIQLEAKIKEVTERA 932
Query: 344 ANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
++ I+ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 933 EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 992
Query: 402 GNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKEL 460
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+L
Sbjct: 993 ETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN-TLTKAKIKLEQQVDDLEGSLEQ-EKKL 1050
Query: 461 RIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
R+ ER +R ++ +LK E + + + +++ K E E+ N+ ++E+ +A I
Sbjct: 1051 RMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQL 1110
Query: 520 GKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS 579
K+ I +L+ARI+++E E++ E+ A+ K R+L+E+ + EE S +
Sbjct: 1111 QKK-IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEM 1169
Query: 580 LEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1170 NKKREAEFQKMRRDLEEATLQHEATAATLRK-----KHADSVAELGEQIDNLQRVKQK 1222
Score = 76.6 bits (180), Expect = 3e-13
Identities = 82/356 (23%), Positives = 168/356 (47%), Gaps = 28/356 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D+ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 979 NKVKNLTEEMAGLDETIAKLTKE--KKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQ 1036
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ + Q ++ + I +L
Sbjct: 1037 VDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNL 1096
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++E+ EQAL ++ ++++ +E Q R+ EL +S+AK E++ + ++ +
Sbjct: 1097 QSKIED-----EQALGIQ--LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL 1149
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A Q E+ E ++ R + + +L+ E ++R + +
Sbjct: 1150 EEISERLEEAGGA-TSAQIEMNKKREAEFQKMRR----DLEEATLQHEATAATLRKKHAD 1204
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI--------KILRKKERQLK 560
+ A +G +R+ KLE +M++E+D + + ET+ K+ R E QL
Sbjct: 1205 SVAELGEQIDNLQRVKQKLEKEKSEMKMEID-DLASNVETVSKAKGNLEKMCRTLEDQLS 1263
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
E+ + EE Q+ I+ L + + + RQL E+E + Q + F +++E
Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIE 1319
Score = 69.3 bits (162), Expect = 4e-11
Identities = 89/491 (18%), Positives = 205/491 (41%), Gaps = 19/491 (3%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEES--RRNVQNERMY 199
+KK ++E+ E ++ L E + + + + + E S + +++E+
Sbjct: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQAL 1106
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVRETS-PTT 256
Q + L + + A+ +KA S SR E I+E R+ E T+
Sbjct: 1107 GIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE--RLEEAGGATS 1164
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ +N + A + +L+E Q + + + K+ + + +L ++ +
Sbjct: 1165 AQIEMNKKREA---EFQKMRRDLEEATLQHEATAATL----RKKHADSVAELGEQIDNLQ 1217
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
++K ++ + K +++++I +L +++ +K +L+K + QL+E+++ +E QR +
Sbjct: 1218 -RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 377 QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLS 436
Q G Q + +++E Q R K++ QQ EE + ++ E L+
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL-KHTVEHLHEEQERIVKIEAVK 495
+ + ++ Y+E + + TE+ + ++ + +R ++E K
Sbjct: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
K L ++ +E V A ++ +L+ ++D+ L+++ A K R
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKC-ASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF 1455
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
++ L E +CEE + Q E S ++K + A +E + Q + +
Sbjct: 1456 DKILAEWKQKCEETHAELEASQK--EARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513
Query: 616 EAAEDRADVAE 626
E ++ +AE
Sbjct: 1514 EISDLTEQIAE 1524
Score = 59.7 bits (138), Expect = 3e-08
Identities = 71/382 (18%), Positives = 165/382 (43%), Gaps = 21/382 (5%)
Query: 271 SYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL 330
++ Q+ ELK +++ ++ + Q+S L E E + K+E+ R K
Sbjct: 1313 AFTQQIEELKRQLEE--EIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKA 1370
Query: 331 QIQITE--LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
++ + + D +T +L++ KK + +L + H + V + Q
Sbjct: 1371 NTEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQN 1429
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK-IEQELA 447
++ L +VE + +R+ ++ E + + E T + S +A+ + EL
Sbjct: 1430 EVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQKEARSLGTELF 1488
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ Y+E +L + +Q E+ E + E +RI ++E +KK +E E +
Sbjct: 1489 KIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQA 1548
Query: 508 RLEEVEAN-AIVGGK---------RIISKLEARIKDMELELDEEKRRHAETIKILRK--- 554
LEE EA+ GK ++ S+++ +I + + E+D+ KR H ++ ++
Sbjct: 1549 ALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLD 1608
Query: 555 -KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR 613
+ R + I ++ + +++ ++ L ++ + R +G+ + + + R
Sbjct: 1609 AEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALR 1668
Query: 614 ELEAAEDRADVAESNLSLIRAK 635
E +++ + E +L++A+
Sbjct: 1669 SQEDLKEQLAMVERRANLLQAE 1690
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 238 bits (582), Expect = 5e-62
Identities = 121/342 (35%), Positives = 207/342 (60%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
D K+ I I + ++AE + +++ R+KKK++ + E+E+ L+ AN+ + +
Sbjct: 1590 DQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1649
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ L + Q H D+ R + +Q + +RR L E+EE+R EQ R ++ E
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ ++ RV L N +L ++K K+E +++ + + ++I +E R A+E+ ++ T+
Sbjct: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAA 1769
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E VK++ +RL+E E A+ GGK+ I KLEAR++++E
Sbjct: 1770 MMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELE 1829
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
E++ E++R+AE +K LRK ER++KE+ Q EED+KNI LQD ++K KV YKRQ
Sbjct: 1830 GEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1889
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E S ++ + R+ Q ELE AE+RAD+AES ++ +R K R
Sbjct: 1890 EAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
Score = 84.6 bits (200), Expect = 1e-15
Identities = 77/373 (20%), Positives = 171/373 (45%), Gaps = 18/373 (4%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ + ++ V K S + + K++LQ ++ +L L ++ N L K
Sbjct: 1392 LEEAKKKLAQRLQAAEEHVEAVNAKCAS-LEKTKQRLQNEVEDLMLDVERTNAACAALDK 1450
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L E + +E +L+ + Q+ +SL E+ +I+ YE++L +
Sbjct: 1451 KQRNFDKILAEWKQKCEETHAELEAS-------QKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 414 VEQQYEESQTRVNELTVINVN-------LSSSKAKIEQELAIVAADYDEITKELRIADER 466
++++ + Q +++LT L K ++EQE + A +E L + +
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563
Query: 467 YQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
R+Q EL + + E+ +I+ +K++ V+++ L+ E + R+
Sbjct: 1564 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLD-AEIRSRNDAIRLKK 1622
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K+E + +ME++L+ R AE ++ R + LK+ I ++ ++ L++ L +
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTST 644
+ ++ + ++ E +Q+ + ++EL A +R + + N SLI K + S
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 645 VPGSQVYLVQESR 657
+ G ++QE+R
Sbjct: 1743 MQGEMEDILQEAR 1755
Score = 82.6 bits (195), Expect = 4e-15
Identities = 64/305 (20%), Positives = 143/305 (46%), Gaps = 12/305 (3%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K +++ +K +L + + E++ ++ L + Q
Sbjct: 837 KLFFKIKPLLKSAET-EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQL 895
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++Q+ + + +Q ++ K +E + +E R + IN L++ K K+E E +
Sbjct: 896 QVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 955
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNI-S 506
+ D D++ L ++ + ++K+ E + E I K+ KK+L E + +
Sbjct: 956 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1015
Query: 507 VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK---EVI 563
++ EE + N + K KLE ++ D+E L++EK+ + + RK E LK E I
Sbjct: 1016 LQAEEDKVNTLTKAK---IKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESI 1072
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
+ E +++ L + L+K ++S + ++ +++ + Q +++ Q +E E+ +
Sbjct: 1073 MDIENEKQQ---LDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129
Query: 624 VAESN 628
++
Sbjct: 1130 AERAS 1134
Score = 80.6 bits (190), Expect = 2e-14
Identities = 73/358 (20%), Positives = 178/358 (49%), Gaps = 16/358 (4%)
Query: 284 KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDV 343
K+ ++ V +L + + ++++ + +AE + IK K+Q++ E++
Sbjct: 877 KELEEKMVTLLKEKN-DLQLQVQAEAEGLADAEERCDQ---LIKTKIQLEAKIKEVTERA 932
Query: 344 ANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
++ I+ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 933 EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 992
Query: 402 GNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKEL 460
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+L
Sbjct: 993 ETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN-TLTKAKIKLEQQVDDLEGSLEQ-EKKL 1050
Query: 461 RIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
R+ ER +R ++ +LK E + + + +++ K E E+ N+ ++E+ +A I
Sbjct: 1051 RMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQL 1110
Query: 520 GKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS 579
K+ I +L+ARI+++E E++ E+ A+ K R+L+E+ + EE S +
Sbjct: 1111 QKK-IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEM 1169
Query: 580 LEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1170 NKKREAEFQKMRRDLEEATLQHEATAATLRK-----KHADSVAELGEQIDNLQRVKQK 1222
Score = 76.6 bits (180), Expect = 3e-13
Identities = 82/356 (23%), Positives = 168/356 (47%), Gaps = 28/356 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D+ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 979 NKVKNLTEEMAGLDETIAKLTKE--KKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQ 1036
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ + Q ++ + I +L
Sbjct: 1037 VDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNL 1096
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++E+ EQAL ++ ++++ +E Q R+ EL +S+AK E++ + ++ +
Sbjct: 1097 QSKIED-----EQALGIQ--LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL 1149
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A Q E+ E ++ R + + +L+ E ++R + +
Sbjct: 1150 EEISERLEEAGGA-TSAQIEMNKKREAEFQKMRR----DLEEATLQHEATAATLRKKHAD 1204
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI--------KILRKKERQLK 560
+ A +G +R+ KLE +M++E+D + + ET+ K+ R E QL
Sbjct: 1205 SVAELGEQIDNLQRVKQKLEKEKSEMKMEID-DLASNVETVSKAKGNLEKMCRTLEDQLS 1263
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
E+ + EE Q+ I+ L + + + RQL E+E + Q + F +++E
Sbjct: 1264 ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIE 1319
Score = 69.3 bits (162), Expect = 4e-11
Identities = 89/491 (18%), Positives = 205/491 (41%), Gaps = 19/491 (3%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEES--RRNVQNERMY 199
+KK ++E+ E ++ L E + + + + + E S + +++E+
Sbjct: 1047 EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQAL 1106
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVRETS-PTT 256
Q + L + + A+ +KA S SR E I+E R+ E T+
Sbjct: 1107 GIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE--RLEEAGGATS 1164
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ +N + A + +L+E Q + + + K+ + + +L ++ +
Sbjct: 1165 AQIEMNKKREA---EFQKMRRDLEEATLQHEATAATL----RKKHADSVAELGEQIDNLQ 1217
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
++K ++ + K +++++I +L +++ +K +L+K + QL+E+++ +E QR +
Sbjct: 1218 -RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 377 QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLS 436
Q G Q + +++E Q R K++ QQ EE + ++ E L+
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL-KHTVEHLHEEQERIVKIEAVK 495
+ + ++ Y+E + + TE+ + ++ + +R ++E K
Sbjct: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK 1396
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
K L ++ +E V A ++ +L+ ++D+ L+++ A K R
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKC-ASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF 1455
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
++ L E +CEE + Q E S ++K + A +E + Q + +
Sbjct: 1456 DKILAEWKQKCEETHAELEASQK--EARSLGTELFKIKNAYEESLDQLETLKRENKNLQQ 1513
Query: 616 EAAEDRADVAE 626
E ++ +AE
Sbjct: 1514 EISDLTEQIAE 1524
Score = 59.7 bits (138), Expect = 3e-08
Identities = 71/382 (18%), Positives = 165/382 (43%), Gaps = 21/382 (5%)
Query: 271 SYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL 330
++ Q+ ELK +++ ++ + Q+S L E E + K+E+ R K
Sbjct: 1313 AFTQQIEELKRQLEE--EIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKA 1370
Query: 331 QIQITE--LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
++ + + D +T +L++ KK + +L + H + V + Q
Sbjct: 1371 NTEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQN 1429
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK-IEQELA 447
++ L +VE + +R+ ++ E + + E T + S +A+ + EL
Sbjct: 1430 EVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQKEARSLGTELF 1488
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ Y+E +L + +Q E+ E + E +RI ++E +KK +E E +
Sbjct: 1489 KIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQA 1548
Query: 508 RLEEVEAN-AIVGGK---------RIISKLEARIKDMELELDEEKRRHAETIKILRK--- 554
LEE EA+ GK ++ S+++ +I + + E+D+ KR H ++ ++
Sbjct: 1549 ALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLD 1608
Query: 555 -KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR 613
+ R + I ++ + +++ ++ L ++ + R +G+ + + + R
Sbjct: 1609 AEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALR 1668
Query: 614 ELEAAEDRADVAESNLSLIRAK 635
E +++ + E +L++A+
Sbjct: 1669 SQEDLKEQLAMVERRANLLQAE 1690
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 234 bits (573), Expect = 6e-61
Identities = 119/325 (36%), Positives = 201/325 (61%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
++AET+ ++EV R+KKK++ + E+E+ L AN+ + QK +K L + Q D+
Sbjct: 1603 LDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1662
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
R + + +RR L E+EE+R EQ R ++ EQ+ E+ RV L N
Sbjct: 1663 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 1722
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
+L + K K+E +L + ++ +E +E R A+E+ ++ T+ E L +EQ+ +E
Sbjct: 1723 TSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1782
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
+KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E EL+ E++R+AE++K +
Sbjct: 1783 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQ 612
RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ E E + ++++ R+ Q
Sbjct: 1843 RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1902
Query: 613 RELEAAEDRADVAESNLSLIRAKHR 637
EL+ AE+RAD+AES ++ +RAK R
Sbjct: 1903 HELDEAEERADIAESQVNKLRAKSR 1927
Score = 83.0 bits (196), Expect = 3e-15
Identities = 76/359 (21%), Positives = 184/359 (51%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N +AE + IK K+Q++ E++
Sbjct: 873 KELEEKMVSLLQEKNDLQLQVQAEQDNLN--DAEERCDQ---LIKNKIQLEAKVKEMNER 927
Query: 343 VANKTNIDLQKTIKKQSLQ--LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L+ +E++ D+++ L + + ++++LT E+ +
Sbjct: 928 LEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N +LS SK K+EQ++ + ++ K+
Sbjct: 988 DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN-SLSKSKVKLEQQVDDLEGSLEQ-EKK 1045
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++E K E ++ + ++E+ +A A+
Sbjct: 1046 VRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQ 1105
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K++ + +ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 1106 LQKKL-KENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 1218
Score = 76.6 bits (180), Expect = 3e-13
Identities = 56/270 (20%), Positives = 131/270 (48%), Gaps = 9/270 (3%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 862 KETLEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
E + E I K+ KK+L+ E ++ +VE + + + KLE ++ D+E
Sbjct: 980 LTEEMAGLDEIIAKLTKEKKALQ-EAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEG 1038
Query: 537 ELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
L++EK+ + + RK E LK E I+ E D+ L++ L+K ++ +
Sbjct: 1039 SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQ---LEEKLKKKEFDINQQNSK 1095
Query: 594 LAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
+ +++ ++ Q +++ Q +E E+ +
Sbjct: 1096 IEDEQALALQLQKKLKENQARIEELEEELE 1125
Score = 70.1 bits (164), Expect = 2e-11
Identities = 81/409 (19%), Positives = 180/409 (44%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L + +E V+ + + +
Sbjct: 1361 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTK 1420
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 1421 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1480
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + E+E++R E
Sbjct: 1481 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVH----ELEKVRKQLE 1536
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ L ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 1537 VEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 1589
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+QRV L+ +++ + +++ VKK +E ++ + ++L A K++
Sbjct: 1590 RNHQRVVDSLQTSLDAETRSRNEVLR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1646
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 1647 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + + Q E+E A AE
Sbjct: 1706 QELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAE 1754
Score = 64.9 bits (151), Expect = 9e-10
Identities = 77/407 (18%), Positives = 173/407 (42%), Gaps = 20/407 (4%)
Query: 271 SYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL 330
SY Q+ +LK +++ + + L + + + + L + E ET+ K+E+ R+ K
Sbjct: 1309 SYTQQMEDLKRQLEE-EGKAKNALAHALQSARHDCDLLREQY-EEETEAKAELQRVLSKA 1366
Query: 331 QIQITE--LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
++ + + D +T +L++ KK + +L + + + V + Q
Sbjct: 1367 NSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK-IEQELA 447
I+ L +VE + +R+ ++ E + + E + + S +A+ + EL
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE-SQSELESSQKEARSLSTELF 1484
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ Y+E + L + +Q E+ E L E + + ++E V+K LE+E +
Sbjct: 1485 KLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQS 1544
Query: 508 RLEEVEAN----------AIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
LEE EA+ A + +I +++E ++ + + E+++ KR H + L +
Sbjct: 1545 ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSL---QT 1601
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
L E + ++ L + ++S R AE + + + ++ Q +L+
Sbjct: 1602 SLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDD 1661
Query: 618 AEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
A D + N++++ ++ + V + SR L+ + L
Sbjct: 1662 AVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQEL 1708
Score = 56.8 bits (131), Expect = 2e-07
Identities = 69/366 (18%), Positives = 165/366 (45%), Gaps = 18/366 (4%)
Query: 274 NQLNELKETVKQFDD--LSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRI-KKKL 330
N E+ + +Q + +V+ L KQ +E +L + + EAE L+ E +I + +L
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQL 1565
Query: 331 QIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI 390
+ + E+ +A K ++++ + + +QT D R L + +
Sbjct: 1566 EFNQIKAEIERKLAEKDE-EMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDL 1624
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVA 450
+ ++ +A + +S++ +++Q ++++ N +L + A +E+ ++
Sbjct: 1625 NEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQ 1684
Query: 451 ADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLE 510
A+ +E LR E+ +R + K + L E ER+ + + SL + K + L
Sbjct: 1685 AELEE----LRAVVEQTERSR---KLAEQELIETSERVQLLHSQNTSLINQKKKMESDLT 1737
Query: 511 EVEA---NAIVGGKRIISKLEARIKD---MELELDEEKRRHAETIKILRKKERQLKEVII 564
++++ A+ + K + I D M EL +E+ A ++ + E+ +K++
Sbjct: 1738 QLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH 1797
Query: 565 QCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
+ +E +Q + + L+K +V + +L ++ + +SV +R+ +R ++ + +
Sbjct: 1798 RLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTE 1857
Query: 624 VAESNL 629
+ NL
Sbjct: 1858 EDKKNL 1863
Score = 56.0 bits (129), Expect = 4e-07
Identities = 83/502 (16%), Positives = 197/502 (39%), Gaps = 28/502 (5%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
K ++E+++D + E +L E + + + R K L +ES +++N+++ +
Sbjct: 1024 KSKVKLEQQVD--DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
+ + ++ A AL K + +R+ E + E + T+ V ++ +
Sbjct: 1082 LKKKEFDINQQNSKIEDEQALALQLQKKLKENQARI-EELEEELEAERTARAK-VEKLRS 1139
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDL-SVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+L +L E+ E +++ SV I + +K+ E +++ + EA + ++
Sbjct: 1140 DLS-------RELEEISERLEEAGGATSVQI--EMNKKREAEFQKMRRDLEEATLQHEAT 1190
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
++KK + EL +D +LQ+ +K + +E + D+V ++ +
Sbjct: 1191 AAALRKKHADSVAELGEQID-------NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKA 1243
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT-------VINVNL 435
++ ++L + E R E+A R Q + QT EL + L
Sbjct: 1244 KANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQL 1303
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ K Q++ + +E K Q + + E EE E +++ V
Sbjct: 1304 TRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVL 1363
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
EV + E + KL R++D E ++ + + K +
Sbjct: 1364 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRL 1423
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ +++++++ E + L + ++ +K++ E + + S R EL
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 616 EAAEDRADVAESNLSLIRAKHR 637
++ + + +L + +++
Sbjct: 1484 FKLKNAYEESLEHLETFKRENK 1505
Score = 54.0 bits (124), Expect = 2e-06
Identities = 38/168 (22%), Positives = 82/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + ++D ++
Sbjct: 906 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKKDIDDLE 960
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1008
Score = 45.6 bits (103), Expect = 6e-04
Identities = 51/199 (25%), Positives = 102/199 (51%), Gaps = 16/199 (8%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
+I++ L A E+ +++ + +Q +++ ++L++ +ER ++ K LE
Sbjct: 860 RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
Query: 501 EVKNISVRLE-EVEANA-IVGGKRII----SKLEARIKDMELELDE-EKRRHA--ETIKI 551
+VK ++ RLE E E NA + KR + S+L+ I D+EL L + EK +HA +K
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQ----DSLEKTSQKV---SIYKRQLAEQEGMSQQS 604
L ++ L E+I + +++K + D L+ KV S K +L +Q + S
Sbjct: 980 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGS 1039
Query: 605 VTRVRRFQRELEAAEDRAD 623
+ + ++ + +LE A+ + +
Sbjct: 1040 LEQEKKVRMDLERAKRKLE 1058
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 234 bits (573), Expect = 6e-61
Identities = 119/325 (36%), Positives = 201/325 (61%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
++AET+ ++EV R+KKK++ + E+E+ L AN+ + QK +K L + Q D+
Sbjct: 1603 LDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1662
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
R + + +RR L E+EE+R EQ R ++ EQ+ E+ RV L N
Sbjct: 1663 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 1722
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
+L + K K+E +L + ++ +E +E R A+E+ ++ T+ E L +EQ+ +E
Sbjct: 1723 TSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1782
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
+KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E EL+ E++R+AE++K +
Sbjct: 1783 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQ 612
RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ E E + ++++ R+ Q
Sbjct: 1843 RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1902
Query: 613 RELEAAEDRADVAESNLSLIRAKHR 637
EL+ AE+RAD+AES ++ +RAK R
Sbjct: 1903 HELDEAEERADIAESQVNKLRAKSR 1927
Score = 81.4 bits (192), Expect = 9e-15
Identities = 75/359 (20%), Positives = 183/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N +AE + IK K+Q++ E++
Sbjct: 873 KELEEKMVSLLQEKNDLQLQVQAEQDNLN--DAEERCDQ---LIKNKIQLEAKVKEMNER 927
Query: 343 VANKTNIDLQKTIKKQSLQ--LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L+ +E++ D+++ L + + ++++LT E+ +
Sbjct: 928 LEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N +LS SK K+EQ++ + ++ K+
Sbjct: 988 DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN-SLSKSKVKLEQQVDDLEGSLEQ-EKK 1045
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++E K E ++ + ++E+ + A+
Sbjct: 1046 VRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQ 1105
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K++ + +ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 1106 LQKKL-KENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 1218
Score = 75.4 bits (177), Expect = 6e-13
Identities = 56/270 (20%), Positives = 131/270 (48%), Gaps = 9/270 (3%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 862 KETLEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
E + E I K+ KK+L+ E ++ +VE + + + KLE ++ D+E
Sbjct: 980 LTEEMAGLDEIIAKLTKEKKALQ-EAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEG 1038
Query: 537 ELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
L++EK+ + + RK E LK E I+ E D+ L++ L+K ++ +
Sbjct: 1039 SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQ---LEEKLKKKEFDINQQNSK 1095
Query: 594 LAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
+ +++ ++ Q +++ Q +E E+ +
Sbjct: 1096 IEDEQVLALQLQKKLKENQARIEELEEELE 1125
Score = 70.1 bits (164), Expect = 2e-11
Identities = 81/409 (19%), Positives = 180/409 (44%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L + +E V+ + + +
Sbjct: 1361 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTK 1420
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 1421 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1480
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + E+E++R E
Sbjct: 1481 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVH----ELEKVRKQLE 1536
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ L ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 1537 VEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 1589
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+QRV L+ +++ + +++ VKK +E ++ + ++L A K++
Sbjct: 1590 RNHQRVVDSLQTSLDAETRSRNEVLR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1646
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 1647 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + + Q E+E A AE
Sbjct: 1706 QELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAE 1754
Score = 64.9 bits (151), Expect = 9e-10
Identities = 77/407 (18%), Positives = 173/407 (42%), Gaps = 20/407 (4%)
Query: 271 SYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL 330
SY Q+ +LK +++ + + L + + + + L + E ET+ K+E+ R+ K
Sbjct: 1309 SYTQQMEDLKRQLEE-EGKAKNALAHALQSARHDCDLLREQY-EEETEAKAELQRVLSKA 1366
Query: 331 QIQITE--LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
++ + + D +T +L++ KK + +L + + + V + Q
Sbjct: 1367 NSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK-IEQELA 447
I+ L +VE + +R+ ++ E + + E + + S +A+ + EL
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE-SQSELESSQKEARSLSTELF 1484
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ Y+E + L + +Q E+ E L E + + ++E V+K LE+E +
Sbjct: 1485 KLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQS 1544
Query: 508 RLEEVEAN----------AIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
LEE EA+ A + +I +++E ++ + + E+++ KR H + L +
Sbjct: 1545 ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSL---QT 1601
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
L E + ++ L + ++S R AE + + + ++ Q +L+
Sbjct: 1602 SLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDD 1661
Query: 618 AEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
A D + N++++ ++ + V + SR L+ + L
Sbjct: 1662 AVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQEL 1708
Score = 56.8 bits (131), Expect = 2e-07
Identities = 69/366 (18%), Positives = 165/366 (45%), Gaps = 18/366 (4%)
Query: 274 NQLNELKETVKQFDD--LSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRI-KKKL 330
N E+ + +Q + +V+ L KQ +E +L + + EAE L+ E +I + +L
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQL 1565
Query: 331 QIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI 390
+ + E+ +A K ++++ + + +QT D R L + +
Sbjct: 1566 EFNQIKAEIERKLAEKDE-EMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDL 1624
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVA 450
+ ++ +A + +S++ +++Q ++++ N +L + A +E+ ++
Sbjct: 1625 NEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQ 1684
Query: 451 ADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLE 510
A+ +E LR E+ +R + K + L E ER+ + + SL + K + L
Sbjct: 1685 AELEE----LRAVVEQTERSR---KLAEQELIETSERVQLLHSQNTSLINQKKKMESDLT 1737
Query: 511 EVEA---NAIVGGKRIISKLEARIKD---MELELDEEKRRHAETIKILRKKERQLKEVII 564
++++ A+ + K + I D M EL +E+ A ++ + E+ +K++
Sbjct: 1738 QLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH 1797
Query: 565 QCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
+ +E +Q + + L+K +V + +L ++ + +SV +R+ +R ++ + +
Sbjct: 1798 RLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTE 1857
Query: 624 VAESNL 629
+ NL
Sbjct: 1858 EDKKNL 1863
Score = 54.4 bits (125), Expect = 1e-06
Identities = 82/502 (16%), Positives = 196/502 (39%), Gaps = 28/502 (5%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
K ++E+++D + E +L E + + + R K L +ES +++N+++ +
Sbjct: 1024 KSKVKLEQQVD--DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
+ + ++ AL K + +R+ E + E + T+ V ++ +
Sbjct: 1082 LKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARI-EELEEELEAERTARAK-VEKLRS 1139
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDL-SVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+L +L E+ E +++ SV I + +K+ E +++ + EA + ++
Sbjct: 1140 DLS-------RELEEISERLEEAGGATSVQI--EMNKKREAEFQKMRRDLEEATLQHEAT 1190
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
++KK + EL +D +LQ+ +K + +E + D+V ++ +
Sbjct: 1191 AAALRKKHADSVAELGEQID-------NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKA 1243
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT-------VINVNL 435
++ ++L + E R E+A R Q + QT EL + L
Sbjct: 1244 KANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQL 1303
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ K Q++ + +E K Q + + E EE E +++ V
Sbjct: 1304 TRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVL 1363
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
EV + E + KL R++D E ++ + + K +
Sbjct: 1364 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRL 1423
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ +++++++ E + L + ++ +K++ E + + S R EL
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 616 EAAEDRADVAESNLSLIRAKHR 637
++ + + +L + +++
Sbjct: 1484 FKLKNAYEESLEHLETFKRENK 1505
Score = 54.0 bits (124), Expect = 2e-06
Identities = 38/168 (22%), Positives = 82/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + ++D ++
Sbjct: 906 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKKDIDDLE 960
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1008
Score = 45.6 bits (103), Expect = 6e-04
Identities = 51/199 (25%), Positives = 102/199 (51%), Gaps = 16/199 (8%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
+I++ L A E+ +++ + +Q +++ ++L++ +ER ++ K LE
Sbjct: 860 RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
Query: 501 EVKNISVRLE-EVEANA-IVGGKRII----SKLEARIKDMELELDE-EKRRHA--ETIKI 551
+VK ++ RLE E E NA + KR + S+L+ I D+EL L + EK +HA +K
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQ----DSLEKTSQKV---SIYKRQLAEQEGMSQQS 604
L ++ L E+I + +++K + D L+ KV S K +L +Q + S
Sbjct: 980 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGS 1039
Query: 605 VTRVRRFQRELEAAEDRAD 623
+ + ++ + +LE A+ + +
Sbjct: 1040 LEQEKKVRMDLERAKRKLE 1058
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain (1437
AA) protein.
Length = 1437
Score = 234 bits (572), Expect = 8e-61
Identities = 119/342 (34%), Positives = 206/342 (60%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
D K+ + + ++AE + +++ R+KKK++ + E+E+ L+ AN+ + +
Sbjct: 1087 DQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNY 1146
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ L E Q H D+ R + +Q + +RR L E+EE+ EQ R ++ E
Sbjct: 1147 RNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAE 1206
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ ++ RV L N +L ++K K+E +++ + ++ +E+ +E R A+E+ ++ T+
Sbjct: 1207 QELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAA 1266
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK+LE VK++ RL+E E A+ GGK+ I KLEAR++++E
Sbjct: 1267 MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE 1326
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
E++ E++R+AE +K LRK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1327 GEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1386
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E S ++++ R+ Q ELE AE+RAD+AES ++ +R K R
Sbjct: 1387 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1428
Score = 86.2 bits (204), Expect = 3e-16
Identities = 64/290 (22%), Positives = 135/290 (46%), Gaps = 6/290 (2%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K +++ +K +L + + E++ ++ L + Q
Sbjct: 333 KLFFKIKPLLKSAET-EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQL 391
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++QS + + EQ ++ K +E + +E R E IN L++ K K+E E +
Sbjct: 392 QVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 451
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNI-S 506
+ D D++ L ++ + ++K+ E + E I K+ KK+L E + +
Sbjct: 452 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDD 511
Query: 507 VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQC 566
++ EE + N + K +KLE ++ D+E L++EK+ + + RK E LK
Sbjct: 512 LQAEEDKVNILTKAK---TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQEST 568
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+++ + L + LEK ++S ++ +++ + Q +++ Q +E
Sbjct: 569 MDNENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIE 618
Score = 78.2 bits (184), Expect = 9e-14
Identities = 72/358 (20%), Positives = 177/358 (49%), Gaps = 16/358 (4%)
Query: 284 KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDV 343
K+ ++ V +L + + ++++ + +AE + + IK K+Q++ E++
Sbjct: 373 KELEEKMVTLLKEKN-DLQLQVQSEADSLADAEERCEQ---LIKNKIQLEAKIKEVTERA 428
Query: 344 ANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
+ I+ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 429 EEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 488
Query: 402 GNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKEL 460
+ + K+++++ ++++ + E +N+ L+ +K K+EQ++ + ++ K+L
Sbjct: 489 ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI-LTKAKTKLEQQVDDLEGSLEQ-EKKL 546
Query: 461 RIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
R+ ER +R ++ +LK E + + +++ + E E+ N+ ++E+ +A I
Sbjct: 547 RMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQL 606
Query: 520 GKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS 579
K+ I +L+ARI+++ E++ E+ A+ K R+L+E+ + EE S +
Sbjct: 607 QKK-IKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVEL 665
Query: 580 LEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + V +R+ + A+ A++ E +L R K +
Sbjct: 666 NKKREAEFQKLRRDLEEATLQHEAMVAALRK-----KHADSMAELGEQIDNLQRVKQK 718
Score = 68.5 bits (160), Expect = 7e-11
Identities = 66/340 (19%), Positives = 161/340 (47%), Gaps = 15/340 (4%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +I+++ R E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 416 QLEAKIKEVTERA-EEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 474
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG-EVEEIRGNYEQALRVKRSVE 415
+ LTE DE +L + ++ + + Q+L + EE + N + K +E
Sbjct: 475 NKVKNLTEEMAGLDETIAKL--SKEKKALQETHQQTLDDLQAEEDKVNI--LTKAKTKLE 530
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
QQ ++ + + + + ++L +K K+E +L + + + + DE+ ++ + E+
Sbjct: 531 QQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKKEFEIS 590
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
+ + + +EQ ++++ K L+ ++ + +E A+ K+ S L ++++
Sbjct: 591 NLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ-RSDLSRELEEIS 649
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
L+E + +++ +K+E + +++ EE + +L K K + +L
Sbjct: 650 ERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK---KHADSMAELG 706
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAK 635
EQ Q+ ++ + + EL+ D D++ + ++ +AK
Sbjct: 707 EQIDNLQRVKQKLEKEKSELKMETD--DLSSNAEAISKAK 744
Score = 64.9 bits (151), Expect = 9e-10
Identities = 78/342 (22%), Positives = 158/342 (46%), Gaps = 28/342 (8%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSI-EIEQLNARVVEAETKLKSEVTRIKKKLQIQIT 335
N++K ++ L I S ++ ++ E Q ++AE + +T+ K KL+ Q+
Sbjct: 475 NKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVD 534
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+LE SL+ K +DL++ +K L Q + + Q ++ + I +L
Sbjct: 535 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKKEFEISNLIS 594
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
++E+ EQA+ ++ ++++ +E Q R+ EL +S+AK E++ + ++ + +E
Sbjct: 595 KIED-----EQAVEIQ--LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 647
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN 515
I++ L A Q EL E ++ R + + +L+ E ++R + ++
Sbjct: 648 ISERLEEAGGA-TSAQVELNKKREAEFQKLRR----DLEEATLQHEAMVAALRKKHADSM 702
Query: 516 AIVGG-----KRIISKLEARIKDMELELDEEKRRHAETIKIL---------RKKERQLKE 561
A +G +R+ KLE ++++E D + +AE I R E Q+ E
Sbjct: 703 AELGEQIDNLQRVKQKLEKEKSELKMETD-DLSSNAEAISKAKGNLEKDGGRSLEDQVSE 761
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+ + EE Q+ I+ L + + Y RQL E++ + Q
Sbjct: 762 LKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQ 803
Score = 60.5 bits (140), Expect = 2e-08
Identities = 104/529 (19%), Positives = 230/529 (43%), Gaps = 44/529 (8%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E A R K A ++A+ L E N+Q + K
Sbjct: 667 KKREAEFQKLRRDL--EEATLQHEAM--VAALRKKHADSMAE--LGEQIDNLQRVKQ-KL 719
Query: 202 DFQASRTLVNRDYTNLSKNVLAKAL--MESKAMNSCDSRVTESIT-ETVRVRETSPTTCV 258
+ + S + D + + ++KA +E S + +V+E T E + R + T
Sbjct: 720 EKEKSELKMETDDLSSNAEAISKAKGNLEKDGGRSLEDQVSELKTKEEEQQRLINDLTAQ 779
Query: 259 -VRINTELPAID------NSYLNQLNELKE-TVKQFDDLSVYILNDSSKQTSIEIEQLNA 310
R+ TE ++ ++QL+ K+ + +Q ++L + ++ + ++ ++
Sbjct: 780 RARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS 839
Query: 311 R--------VVEAETKLKSEVTRIKKKLQIQITELELSLDV-ANKTNIDLQKTIKKQSLQ 361
R E E + K+E+ R K ++ + + + A + +L++ KK + +
Sbjct: 840 RHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTNTETDAIQRTEELEEAKKKLAQR 899
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + H + V + Q ++ L +VE + +R+ ++ E
Sbjct: 900 LQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEW 959
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E T + S +++ + EL V Y+E +L + +Q E+ E
Sbjct: 960 KQKYEE-TQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQ 1018
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN-AIVGGK---------RIISKLEAR 530
+ E ++I ++E +KK +E E I LEE EA+ GK ++ S+++ +
Sbjct: 1019 IAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRK 1078
Query: 531 IKDMELELDEEKRRHAETIKILRK----KERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
I + + E+D+ KR H ++ ++ + R + + ++ + +++ ++ L ++
Sbjct: 1079 IAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRL 1138
Query: 587 VSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAK 635
+ R +G+ +++ + R E +++ + E +L++A+
Sbjct: 1139 AAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAE 1187
Score = 46.4 bits (105), Expect = 3e-04
Identities = 45/249 (18%), Positives = 112/249 (44%), Gaps = 15/249 (6%)
Query: 275 QLNELKETVKQFD---DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ EL T++Q + ++ L D+S++ + + N ++ + KL+++V++++ +++
Sbjct: 1187 EIEELWATLEQTERSRKIAEQELLDASERVQL-LHTQNTSLINTKKKLENDVSQLQSEVE 1245
Query: 332 IQITELELSLDVANKTNID---LQKTIKKQ---SLQLTEIQTHYDEVQRQLQVTLDQYGV 385
I E + + A K D + + +KK+ S L ++ + ++ + LQ LD+
Sbjct: 1246 EVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1305
Query: 386 -----AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+++IQ L V E+ G E + + + + RV ELT +
Sbjct: 1306 LALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVL 1365
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
+++ + + A ++ A+E+ ++ + L E +ER E+ L +
Sbjct: 1366 RLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRV 1425
Query: 501 EVKNISVRL 509
+ + + ++
Sbjct: 1426 KSREVHTKI 1434
>X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac mRNA
for myosin heavy chain light meromyosin region. ).
Length = 635
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 284 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 343
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 344 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 403
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 404 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 463
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 464 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 523
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 524 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 583
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 584 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 629
Score = 79.4 bits (187), Expect = 4e-14
Identities = 79/374 (21%), Positives = 170/374 (45%), Gaps = 20/374 (5%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ + +++ VEA S + + K +LQ +I +L + ++ +N L K
Sbjct: 86 LEEAKKKLAQRLQEAE-EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDK 144
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L E + Y+E Q +L+ +Q+ +SL+ E+ +++ YE++L +
Sbjct: 145 KQRNFDKILAEWKQKYEESQSELE-------SSQKEARSLSTELFKLKNAYEESLEHLET 197
Query: 414 VEQQYEESQTRVNELT--------VINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
+++ + Q +++LT I+ L + ++E E + + +E L +
Sbjct: 198 FKRENKNLQEEISDLTEQLGSSGKTIH-ELEKVRKQLEAEKMELQSALEEAEASLEHEEG 256
Query: 466 RYQRVQTELKH-TVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ R Q E E + QE+ ++E K++ V ++ L + E + R+
Sbjct: 257 KILRAQLEFNQIKAEIERKRQEKDEEMEQAKRNHLRVVDSLQTSL-DAETRSRNEALRVK 315
Query: 525 SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS 584
K+E + +ME++L R AE K ++ + LK+ IQ ++ + L++++
Sbjct: 316 KKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVE 375
Query: 585 QKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTS 643
++ ++ + +L E + +Q+ + ++EL +R + S N SLI K + S
Sbjct: 376 RRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLS 435
Query: 644 TVPGSQVYLVQESR 657
+ VQE R
Sbjct: 436 QLQTEVEEAVQECR 449
Score = 62.9 bits (146), Expect = 3e-09
Identities = 80/410 (19%), Positives = 171/410 (41%), Gaps = 18/410 (4%)
Query: 228 ESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD 287
E++A ++++ +E + R T + R EL +L E +E V+ +
Sbjct: 50 ETEAKARLQGDLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQEAEEAVEAVN 108
Query: 288 DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKT 347
L + + EIE L V E + + + ++ + E + + +
Sbjct: 109 -AKCSSLEKTKHRLQNEIEDLMVDV-ERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 166
Query: 348 NIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQA 407
QK + S +L +++ Y+E L+ + Q I LT ++ +
Sbjct: 167 LESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHEL 226
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERY 467
+V++ +E + E Q+ + E +L + KI + EI ++ + DE
Sbjct: 227 EKVRKQLEAEKMELQSALEEA---EASLEHEEGKILRAQLEFNQIKAEIERKRQEKDEEM 283
Query: 468 QRVQTELKHTVEHLHE--EQERIVKIEA--VKKSLEIEVKNISVRLEEVEANAIVGGKRI 523
++ + V+ L + E + EA VKK +E ++ + ++L A K++
Sbjct: 284 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 343
Query: 524 ISKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLL 576
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L
Sbjct: 344 KS-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 402
Query: 577 QDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
+ L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 403 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 452
Score = 38.7 bits (86), Expect = 0.065
Identities = 49/265 (18%), Positives = 111/265 (41%), Gaps = 26/265 (9%)
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV 430
+++RQL+ + +QS + + +R YE+ K ++ +L+
Sbjct: 14 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKARLQ----------GDLSK 63
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
N ++ + K E + + +E K+L QR+Q E + VE ++ +
Sbjct: 64 ANSEVAQWRTKYETDAIQRTEELEEAKKKLA------QRLQ-EAEEAVEAVN---AKCSS 113
Query: 491 IEAVKKSLEIEVKNISVRLEEVEANAIVGGK------RIISKLEARIKDMELELDEEKRR 544
+E K L+ E++++ V +E A A K +I+++ + + ++ + EL+ ++
Sbjct: 114 LEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKE 173
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
L K + +E + E ++ LQ+ + ++++ + + E E + +Q
Sbjct: 174 ARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQL 233
Query: 605 VTRVRRFQRELEAAEDRADVAESNL 629
Q LE AE + E +
Sbjct: 234 EAEKMELQSALEEAEASLEHEEGKI 258
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1823
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1824 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1883
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1884 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1929
Score = 80.6 bits (190), Expect = 2e-14
Identities = 74/359 (20%), Positives = 183/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N + +AE + IK K+Q++ E++
Sbjct: 871 KELEEKMVSLLQEKNDLQLQVQAEQDN--LADAEERCDQ---LIKNKIQLEAKVKEMNER 925
Query: 343 VANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 926 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 985
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+
Sbjct: 986 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN-TLTKAKVKLEQQVDDLEGSLEQ-EKK 1043
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++ K + E+ ++ R+E+ +A
Sbjct: 1044 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQ 1103
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K+ + +L+ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 1104 LQKK-LKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 1216
Score = 78.2 bits (184), Expect = 9e-14
Identities = 57/272 (20%), Positives = 131/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 860 KEALEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDL 1034
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D++ L + L+K +++
Sbjct: 1035 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ---LDERLKKKDFELNALN 1091
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Score = 74.9 bits (176), Expect = 8e-13
Identities = 83/352 (23%), Positives = 158/352 (44%), Gaps = 40/352 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +++++N R+ E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 914 QLEAKVKEMNERL-EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 357 KQSLQLTEIQTHYDEV-----------QRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE+ Q Q LD + ++ +LT +V+
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +V+ +E+ + + + ++L + K ++++ L D++
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLK--KKDFELNAL 1090
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHE--EQERI--VKIEAVKKSLEIEVKNISVRL 509
RI DE + Q+ EL+ +E L E E ER K+E ++ L E++ IS RL
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERL 1150
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 1151 EEA-GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH---ADSVAELGEQ 1206
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
N+ ++ LEK + S +K +L + +Q + ++ ED+
Sbjct: 1207 IDNLQRVKQKLEK---EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
Score = 73.3 bits (172), Expect = 2e-12
Identities = 80/355 (22%), Positives = 161/355 (45%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL + +++AK+E+ + ++ +
Sbjct: 1091 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSREL 1143
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A VQ E+ E ++ R + + +L+ E ++R + +
Sbjct: 1144 EEISERLEEAGGA-TSVQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 1198
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 1313
Score = 66.1 bits (154), Expect = 4e-10
Identities = 119/554 (21%), Positives = 234/554 (42%), Gaps = 44/554 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 1165 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 1218
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 1396
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 1457 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 1576 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV 650
R AE + + + ++ Q +L+ A D + N++++ ++ + V
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
Query: 651 YLVQESRALSSERL 664
+ SR L+ + L
Sbjct: 1693 EQTERSRKLAEQEL 1706
Score = 65.7 bits (153), Expect = 5e-10
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L E +E V+ + + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1478
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + I E+E++R E
Sbjct: 1479 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLE 1534
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 1535 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 1587
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1644
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 1645 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
Score = 58.8 bits (136), Expect = 6e-08
Identities = 88/461 (19%), Positives = 184/461 (39%), Gaps = 25/461 (5%)
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
AKA Q +L ++ V R RT + +K LA+ L E++ +
Sbjct: 1353 AKAELQRVLSKANSEVAQWRTKYETDAIQRT----EELEEAKKKLAQRLQEAEEAVEAVN 1408
Query: 238 RVTESITETVRVRETSPTTCVV---RINTELPAIDNSYLNQLNELKETVKQFDDLSVYIL 294
S+ +T + +V R N A+D N L E +++++ +
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + S+ E + E+ E R K LQ +I++L L + KT +L+K
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA-- 407
K+ + E+Q+ +E + L+ + AQ + E+E E EQA
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 408 --LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
LRV S++ + NE + + ++E +L+ E K+++
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1648
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ Q +L V + +E I +E L+ E++ + +E+ E + + + +I
Sbjct: 1649 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
Query: 526 KLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E R++ + + ++++K+ A+ L + + +++E + +C ++
Sbjct: 1709 TSE-RVQLLHSQNTSLINQKKKMDAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++++ + A E M + ++ Q L+ AE A
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804
Score = 51.6 bits (118), Expect = 9e-06
Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + + D ++
Sbjct: 904 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKRDIDDLE 958
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 32.3 bits (70), Expect = 5.6
Identities = 52/240 (21%), Positives = 105/240 (43%), Gaps = 18/240 (7%)
Query: 402 GNYEQALRVKRSV---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
G++ Q R+ E Q+ +S+ +L + ++++ ++ K A + +
Sbjct: 716 GDFRQRYRILNPAAIPEGQFIDSRKGAEKL-LSSLDIDHNQYKFGHTKVFFKAGLLGLLE 774
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
E+R DER R+ T ++ + + + ++E KK LE + S+ + + A +
Sbjct: 775 EMR--DERLSRIITRIQA------QSRGVLARME-YKKLLE---RRDSLLVIQWNIRAFM 822
Query: 519 GGKRII-SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
G K KL +IK + + EK + + R KE K + E ++K +SLLQ
Sbjct: 823 GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ + Q V + LA+ E Q + + + +++ +R + E + + AK R
Sbjct: 883 EKNDLQLQ-VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKR 941
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1823
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1824 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1883
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1884 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1929
Score = 80.6 bits (190), Expect = 2e-14
Identities = 74/359 (20%), Positives = 183/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N + +AE + IK K+Q++ E++
Sbjct: 871 KELEEKMVSLLQEKNDLQLQVQAEQDN--LADAEERCDQ---LIKNKIQLEAKVKEMNER 925
Query: 343 VANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 926 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 985
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+
Sbjct: 986 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN-TLTKAKVKLEQQVDDLEGSLEQ-EKK 1043
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++ K + E+ ++ R+E+ +A
Sbjct: 1044 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQ 1103
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K+ + +L+ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 1104 LQKK-LKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 1216
Score = 78.2 bits (184), Expect = 9e-14
Identities = 57/272 (20%), Positives = 131/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 860 KEALEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDL 1034
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D++ L + L+K +++
Sbjct: 1035 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ---LDERLKKKDFELNALN 1091
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Score = 74.9 bits (176), Expect = 8e-13
Identities = 83/352 (23%), Positives = 158/352 (44%), Gaps = 40/352 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +++++N R+ E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 914 QLEAKVKEMNERL-EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 357 KQSLQLTEIQTHYDEV-----------QRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE+ Q Q LD + ++ +LT +V+
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +V+ +E+ + + + ++L + K ++++ L D++
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLK--KKDFELNAL 1090
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHE--EQERI--VKIEAVKKSLEIEVKNISVRL 509
RI DE + Q+ EL+ +E L E E ER K+E ++ L E++ IS RL
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERL 1150
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 1151 EEA-GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH---ADSVAELGEQ 1206
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
N+ ++ LEK + S +K +L + +Q + ++ ED+
Sbjct: 1207 IDNLQRVKQKLEK---EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
Score = 73.3 bits (172), Expect = 2e-12
Identities = 80/355 (22%), Positives = 161/355 (45%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL + +++AK+E+ + ++ +
Sbjct: 1091 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSREL 1143
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A VQ E+ E ++ R + + +L+ E ++R + +
Sbjct: 1144 EEISERLEEAGGA-TSVQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 1198
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 1313
Score = 66.1 bits (154), Expect = 4e-10
Identities = 119/554 (21%), Positives = 234/554 (42%), Gaps = 44/554 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 1165 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 1218
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 1396
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 1457 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 1576 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV 650
R AE + + + ++ Q +L+ A D + N++++ ++ + V
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
Query: 651 YLVQESRALSSERL 664
+ SR L+ + L
Sbjct: 1693 EQTERSRKLAEQEL 1706
Score = 65.7 bits (153), Expect = 5e-10
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L E +E V+ + + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1478
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + I E+E++R E
Sbjct: 1479 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLE 1534
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 1535 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 1587
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1644
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 1645 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
Score = 58.8 bits (136), Expect = 6e-08
Identities = 88/461 (19%), Positives = 184/461 (39%), Gaps = 25/461 (5%)
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
AKA Q +L ++ V R RT + +K LA+ L E++ +
Sbjct: 1353 AKAELQRVLSKANSEVAQWRTKYETDAIQRT----EELEEAKKKLAQRLQEAEEAVEAVN 1408
Query: 238 RVTESITETVRVRETSPTTCVV---RINTELPAIDNSYLNQLNELKETVKQFDDLSVYIL 294
S+ +T + +V R N A+D N L E +++++ +
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + S+ E + E+ E R K LQ +I++L L + KT +L+K
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA-- 407
K+ + E+Q+ +E + L+ + AQ + E+E E EQA
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 408 --LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
LRV S++ + NE + + ++E +L+ E K+++
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1648
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ Q +L V + +E I +E L+ E++ + +E+ E + + + +I
Sbjct: 1649 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
Query: 526 KLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E R++ + + ++++K+ A+ L + + +++E + +C ++
Sbjct: 1709 TSE-RVQLLHSQNTSLINQKKKMDAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++++ + A E M + ++ Q L+ AE A
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804
Score = 51.6 bits (118), Expect = 9e-06
Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + + D ++
Sbjct: 904 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKRDIDDLE 958
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 32.3 bits (70), Expect = 5.6
Identities = 52/240 (21%), Positives = 105/240 (43%), Gaps = 18/240 (7%)
Query: 402 GNYEQALRVKRSV---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
G++ Q R+ E Q+ +S+ +L + ++++ ++ K A + +
Sbjct: 716 GDFRQRYRILNPAAIPEGQFIDSRKGAEKL-LSSLDIDHNQYKFGHTKVFFKAGLLGLLE 774
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
E+R DER R+ T ++ + + + ++E KK LE + S+ + + A +
Sbjct: 775 EMR--DERLSRIITRIQA------QSRGVLARME-YKKLLE---RRDSLLVIQWNIRAFM 822
Query: 519 GGKRII-SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
G K KL +IK + + EK + + R KE K + E ++K +SLLQ
Sbjct: 823 GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ + Q V + LA+ E Q + + + +++ +R + E + + AK R
Sbjct: 883 EKNDLQLQ-VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKR 941
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 233 bits (569), Expect = 2e-60
Identities = 118/342 (34%), Positives = 206/342 (60%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
D K+ + + ++AE + +++ R+KKK++ + E+E+ L+ AN+ + +
Sbjct: 1587 DQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNY 1646
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ L E Q H D+ R + +Q + +RR L E+EE+ EQ R ++ E
Sbjct: 1647 RNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAE 1706
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ ++ RV L N +L ++K K+E +++ + ++ +E+ +E R A+E+ ++ T+
Sbjct: 1707 QELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAA 1766
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK+LE VK++ RL+E E A+ GGK+ I KLEAR++++E
Sbjct: 1767 MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE 1826
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
E++ E++R+AE +K LRK +R++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1827 GEVENEQKRNAEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E S ++++ R+ Q ELE AE+RAD+AES ++ +R K R
Sbjct: 1887 EAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
Score = 91.1 bits (216), Expect = 1e-17
Identities = 78/373 (20%), Positives = 174/373 (46%), Gaps = 18/373 (4%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ + +++ V K S + + K++LQ ++ +L L ++ +N L K
Sbjct: 1389 LEEAKKKLAQRLQEAEEHVEAVNAKCAS-LEKTKQRLQNEVEDLMLDVERSNAACAALDK 1447
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L+E + Y+E Q +L+ +Q+ +SL+ E+ +++ YE++L +
Sbjct: 1448 KQRNFDKVLSEWKQKYEETQAELE-------ASQKESRSLSTELFKVKNVYEESLDQLET 1500
Query: 414 VEQQYEESQTRVNELTVINV-------NLSSSKAKIEQELAIVAADYDEITKELRIADER 466
+ + ++ Q +++LT L K ++EQE + A +E L + +
Sbjct: 1501 LRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
Query: 467 YQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
R+Q EL + + E+ +I+ +K++ V+ + L + E + R+
Sbjct: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTL-DAEIRSRNDALRVKK 1619
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K+E + +ME++L+ R AE+++ R + LKE + ++ + L++ L +
Sbjct: 1620 KMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVER 1679
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTST 644
+ ++ + ++ E +Q+ + ++EL A +R + + N SLI K + S
Sbjct: 1680 RANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQ 1739
Query: 645 VPGSQVYLVQESR 657
+ ++QESR
Sbjct: 1740 LQSEVEEVIQESR 1752
Score = 85.0 bits (201), Expect = 8e-16
Identities = 64/290 (22%), Positives = 135/290 (46%), Gaps = 6/290 (2%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K +++ +K +L + + E++ ++ L + Q
Sbjct: 834 KLFFKIKPLLKSAET-EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQL 892
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++QS + + EQ ++ K +E + +E R E IN L++ K K+E E +
Sbjct: 893 QVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 952
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNI-S 506
+ D D++ L +++ + ++K+ E + E I K+ KK+L E + +
Sbjct: 953 LKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDD 1012
Query: 507 VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQC 566
++ EE + N + K +KLE ++ D+E L++EK+ + + RK E LK
Sbjct: 1013 LQAEEDKVNILTKAK---TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQEST 1069
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ + + L + LEK ++S ++ +++ + Q +++ Q +E
Sbjct: 1070 MDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIE 1119
Score = 78.6 bits (185), Expect = 7e-14
Identities = 73/358 (20%), Positives = 177/358 (49%), Gaps = 16/358 (4%)
Query: 284 KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDV 343
K+ ++ V +L + + ++++ + +AE + + IK K+Q++ E++
Sbjct: 874 KELEEKMVTLLKEKN-DLQLQVQSEADSLADAEERCEQ---LIKNKIQLEAKIKEVTERA 929
Query: 344 ANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
+ I+ + T KK+ L + +E++ D+++ L Q + ++++LT E+ +
Sbjct: 930 EEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLD 989
Query: 402 GNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKEL 460
+ + K+++++ ++++ + E +N+ L+ +K K+EQ++ + ++ K+L
Sbjct: 990 ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI-LTKAKTKLEQQVDDLEGSLEQ-EKKL 1047
Query: 461 RIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
R+ ER +R ++ +LK E + + +++ + E E+ N+ ++E+ +A I
Sbjct: 1048 RMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQL 1107
Query: 520 GKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS 579
K+ I +L+ARI+++ E++ E+ A+ K R+L+E+ + EE S +
Sbjct: 1108 QKK-IKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVEL 1166
Query: 580 LEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + V +R+ + A+ A++ E +L R K +
Sbjct: 1167 NKKREAEFQKLRRDLEEATLQHEAMVAALRK-----KHADSMAELGEQIDNLQRVKQK 1219
Score = 75.8 bits (178), Expect = 5e-13
Identities = 99/496 (19%), Positives = 225/496 (45%), Gaps = 29/496 (5%)
Query: 147 QEIEKELDLYEKEV-NLGSELRQKAAM--YRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
Q+++++L+ E E+ NL S++ + A+ K K + Q +EE ++ ER +
Sbjct: 1077 QQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKEL-QARIEELGEEIEAERASRAKA 1135
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
+ R+ ++R+ +S+ L +A + A + + E+ + +R R+ T ++
Sbjct: 1136 EKQRSDLSRELEEISER-LEEAGGATSAQVELNKK-REAEFQKLR-RDLEEAT--LQHEA 1190
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+ A+ + + + EL E + + + + S + +E + L++ EA +K K +
Sbjct: 1191 MVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKS-ELKMETDDLSSNA-EAISKAKGHL 1248
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++ + L+ Q++ L+ + + Q+ I + Q +QT E RQL
Sbjct: 1249 EKMCRSLEDQVSGLKTKEE-------EQQRLINDLTAQRARLQTEAGEYSRQLDEQDALV 1301
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
R Q+ T ++EE++ E+ + K ++ + S+ + L KA+++
Sbjct: 1302 SQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQ 1361
Query: 444 QELAIVAADYDE-ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
+ L+ ++ + TK A +R + ++ K + L E +E + + A SLE
Sbjct: 1362 RALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTK 1421
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET---IKILRKKERQL 559
+ + +E++ + + + L+ + ++ + L E K+++ ET ++ +K+ R L
Sbjct: 1422 QRLQNEVEDLMLD-VERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSL 1480
Query: 560 KEVIIQC----EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ + EE + L+ + + Q++S Q+AE G + ++++ Q E
Sbjct: 1481 STELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAE-GGKQIHELEKIKK-QVEQ 1538
Query: 616 EAAEDRADVAESNLSL 631
E E +A + E+ SL
Sbjct: 1539 EKCEIQAALEEAEASL 1554
Score = 71.3 bits (167), Expect = 1e-11
Identities = 67/340 (19%), Positives = 164/340 (48%), Gaps = 15/340 (4%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKT--NIDLQKTIKK 357
Q +I+++ R E E ++ +E+T K+KL+ + +EL+ +D T ++ QK +
Sbjct: 917 QLEAKIKEVTERA-EEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATE 975
Query: 358 QSLQ-LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG-EVEEIRGNYEQALRVKRSVE 415
++ LTE DE +L + ++ + + Q+L + EE + N + K +E
Sbjct: 976 NKVKNLTEEMAGLDETIAKL--SKEKKALQETHQQTLDDLQAEEDKVNI--LTKAKTKLE 1031
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
QQ ++ + + + + ++L +K K+E +L + ++ + + DE+ ++ + E+
Sbjct: 1032 QQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEIS 1091
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
+ + + +EQ ++++ K L+ ++ + +E A+ K+ S L ++++
Sbjct: 1092 NLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ-RSDLSRELEEIS 1150
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
L+E + +++ +K+E + +++ EE + +L K K + +L
Sbjct: 1151 ERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK---KHADSMAELG 1207
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAK 635
EQ Q+ ++ + + EL+ D D++ + ++ +AK
Sbjct: 1208 EQIDNLQRVKQKLEKEKSELKMETD--DLSSNAEAISKAK 1245
Score = 69.7 bits (163), Expect = 3e-11
Identities = 79/341 (23%), Positives = 160/341 (46%), Gaps = 27/341 (7%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSI-EIEQLNARVVEAETKLKSEVTRIKKKLQIQIT 335
N++K ++ L I S ++ ++ E Q ++AE + +T+ K KL+ Q+
Sbjct: 976 NKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVD 1035
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+LE SL+ K +DL++ +K L Q +++ Q ++ + I +L
Sbjct: 1036 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLIS 1095
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
++E+ EQA+ ++ ++++ +E Q R+ EL +S+AK E++ + ++ + +E
Sbjct: 1096 KIED-----EQAVEIQ--LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 1148
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN 515
I++ L A Q EL E ++ R + + +L+ E ++R + ++
Sbjct: 1149 ISERLEEAGGA-TSAQVELNKKREAEFQKLRR----DLEEATLQHEAMVAALRKKHADSM 1203
Query: 516 AIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI--------KILRKKERQLKEV 562
A +G +R+ KLE ++++E D + +AE I K+ R E Q+ +
Sbjct: 1204 AELGEQIDNLQRVKQKLEKEKSELKMETD-DLSSNAEAISKAKGHLEKMCRSLEDQVSGL 1262
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+ EE Q+ I+ L + + Y RQL EQ+ + Q
Sbjct: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQ 1303
Score = 61.3 bits (142), Expect = 1e-08
Identities = 64/339 (18%), Positives = 151/339 (44%), Gaps = 19/339 (5%)
Query: 314 EAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
E E + K+E+ R K ++ + + D +T +L++ KK + +L E + H +
Sbjct: 1351 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQEAEEHVEA 1409
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
V + Q ++ L +VE + +R+ ++ E + + E T
Sbjct: 1410 VNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEE-TQA 1468
Query: 432 NVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
+ S +++ + EL V Y+E +L ++ +Q E+ E + E ++I +
Sbjct: 1469 ELEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHE 1528
Query: 491 IEAVKKSLEIEVKNISVRLEEVEAN-AIVGGK---------RIISKLEARIKDMELELDE 540
+E +KK +E E I LEE EA+ GK ++ S+++ +I + + E+D+
Sbjct: 1529 LEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1588
Query: 541 EKRRHAETIKILRK----KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
KR H ++ ++ + R + + ++ + +++ ++ L ++ + R
Sbjct: 1589 LKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRN 1648
Query: 597 QEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAK 635
+G+ +++ + R E +++ + E +L++A+
Sbjct: 1649 TQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAE 1687
Score = 45.6 bits (103), Expect = 6e-04
Identities = 45/249 (18%), Positives = 111/249 (44%), Gaps = 15/249 (6%)
Query: 275 QLNELKETVKQFD---DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ EL T++Q + ++ L D+S++ + + N ++ + KL+++V++++ +++
Sbjct: 1687 EIEELWATLEQTERSRKIAEQELLDASERVQL-LHTQNTSLINTKKKLENDVSQLQSEVE 1745
Query: 332 IQITELELSLDVANKTNID---LQKTIKKQ---SLQLTEIQTHYDEVQRQLQVTLDQYGV 385
I E + + A K D + + +KK+ S L ++ + ++ + LQ LD+
Sbjct: 1746 EVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1805
Query: 386 -----AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+++IQ L V E+ G E + + + RV ELT +
Sbjct: 1806 LALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHDRRVKELTYQTEEDRKNVL 1865
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
+++ + + A ++ A+E+ ++ + L E +ER E+ L +
Sbjct: 1866 RLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRV 1925
Query: 501 EVKNISVRL 509
+ + + ++
Sbjct: 1926 KSREVHTKI 1934
>M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myosin
heavy chain mRNA, 3' end. ).
Length = 524
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 173 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 232
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 233 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 292
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 293 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 352
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 353 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 412
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 413 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 472
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 473 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 518
Score = 61.7 bits (143), Expect = 8e-09
Identities = 69/347 (19%), Positives = 157/347 (45%), Gaps = 29/347 (8%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTNID 350
L + + +++E+ NA + K ++ + K+K + +ELE S A + +
Sbjct: 10 LQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTE 69
Query: 351 LQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE-Q 406
L K L ++T E +Q ++ +Q G + + I E+E++R E +
Sbjct: 70 LFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLEAE 125
Query: 407 ALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADER 466
+ ++ ++E+ + ++ + + KA+IE+ +A E +E+ A
Sbjct: 126 KMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERNVA-------EKDEEMEQAKRN 178
Query: 467 YQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISK 526
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++ S
Sbjct: 179 HLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS- 234
Query: 527 LEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQDS 579
L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 235 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQE 294
Query: 580 LEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 295 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 341
Score = 58.4 bits (135), Expect = 8e-08
Identities = 72/378 (19%), Positives = 155/378 (41%), Gaps = 18/378 (4%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
V R N A+D N L E +++++ + + + S+ E + E+
Sbjct: 21 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 80
Query: 318 KLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
E R K LQ +I++L L + KT +L+K K+ + E+Q+ +E + L
Sbjct: 81 LEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASL 140
Query: 377 QVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA----LRVKRSVEQQYEESQTRVNEL 428
+ + AQ + E+E E EQA LRV S++ + NE
Sbjct: 141 EHEEGKILRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 200
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+ + ++E +L+ E K+++ + Q +L V + +E I
Sbjct: 201 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENI 260
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE----LDEEKRR 544
+E L+ E++ + +E+ E + + + +I E R++ + + ++++K+
Sbjct: 261 AIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE-RVQLLHSQNTSLINQKKKM 319
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
A+ L + + +++E + +C ++ ++++ + A E M +
Sbjct: 320 DAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM 375
Query: 605 VTRVRRFQRELEAAEDRA 622
++ Q L+ AE A
Sbjct: 376 EQTIKDLQHRLDEAEQIA 393
Score = 54.0 bits (124), Expect = 2e-06
Identities = 58/305 (19%), Positives = 131/305 (42%), Gaps = 23/305 (7%)
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
++ + +LQ ++ V R + +++ + N+++ L +Q+YEESQ+ +
Sbjct: 4 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA---EWKQKYEESQSELESSQ 60
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
+LS+ K++ Y+E + L + +Q E+ E L + I
Sbjct: 61 KEARSLSTELFKLKNA-------YEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH 113
Query: 490 KIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEARIKDMELELD 539
++E V+K LE E + LEE EA+ A + +I +++E + + + E++
Sbjct: 114 ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEEME 173
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+ KR H ++++ + L E + ++ L + ++S R AE +
Sbjct: 174 QAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQK 230
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRAL 659
+ + ++ Q +L+ A D + N++++ ++ + V + SR L
Sbjct: 231 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 290
Query: 660 SSERL 664
+ + L
Sbjct: 291 AEQEL 295
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1823
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1824 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1883
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1884 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1929
Score = 80.2 bits (189), Expect = 2e-14
Identities = 74/359 (20%), Positives = 183/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N + +AE + IK K+Q++ E++
Sbjct: 871 KELEEKMVSLLQEKNDLQLQVQAEQDN--LADAEERCDQ---LIKNKIQLEAKVKEMNER 925
Query: 343 VANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 926 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 985
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+
Sbjct: 986 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN-TLTKAKVKLEQQVDDLEGSLEQ-EKK 1043
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++ K + E+ ++ R+E+ +A
Sbjct: 1044 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQ 1103
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K+ + +L+ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 1104 LQKK-LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 1216
Score = 78.2 bits (184), Expect = 9e-14
Identities = 57/272 (20%), Positives = 131/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 860 KEALEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDL 1034
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D++ L + L+K +++
Sbjct: 1035 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ---LDERLKKKDFELNALN 1091
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Score = 74.5 bits (175), Expect = 1e-12
Identities = 82/352 (23%), Positives = 157/352 (44%), Gaps = 40/352 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +++++N R+ E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 914 QLEAKVKEMNERL-EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 357 KQSLQLTEIQTHYDEV-----------QRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE+ Q Q LD + ++ +LT +V+
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +V+ +E+ + + + ++L + K ++++ L D++
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLK--KKDFELNAL 1090
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRL 509
RI DE + Q+ EL+ +E L EE E K+E ++ L E++ IS RL
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 1151 EEA-GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH---ADSVAELGEQ 1206
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
N+ ++ LEK + S +K +L + +Q + ++ ED+
Sbjct: 1207 IDNLQRVKQKLEK---EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
Score = 72.1 bits (169), Expect = 6e-12
Identities = 80/355 (22%), Positives = 160/355 (45%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL +++AK+E+ + ++ +
Sbjct: 1091 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 1143
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A VQ E+ E ++ R + + +L+ E ++R + +
Sbjct: 1144 EEISERLEEAGGA-TSVQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 1198
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 1313
Score = 66.1 bits (154), Expect = 4e-10
Identities = 119/554 (21%), Positives = 234/554 (42%), Gaps = 44/554 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 1165 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 1218
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 1396
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 1457 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 1576 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV 650
R AE + + + ++ Q +L+ A D + N++++ ++ + V
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
Query: 651 YLVQESRALSSERL 664
+ SR L+ + L
Sbjct: 1693 EQTERSRKLAEQEL 1706
Score = 65.7 bits (153), Expect = 5e-10
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L E +E V+ + + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1478
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + I E+E++R E
Sbjct: 1479 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLE 1534
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 1535 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 1587
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1644
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 1645 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
Score = 58.8 bits (136), Expect = 6e-08
Identities = 88/461 (19%), Positives = 184/461 (39%), Gaps = 25/461 (5%)
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
AKA Q +L ++ V R RT + +K LA+ L E++ +
Sbjct: 1353 AKAELQRVLSKANSEVAQWRTKYETDAIQRT----EELEEAKKKLAQRLQEAEEAVEAVN 1408
Query: 238 RVTESITETVRVRETSPTTCVV---RINTELPAIDNSYLNQLNELKETVKQFDDLSVYIL 294
S+ +T + +V R N A+D N L E +++++ +
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + S+ E + E+ E R K LQ +I++L L + KT +L+K
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA-- 407
K+ + E+Q+ +E + L+ + AQ + E+E E EQA
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 408 --LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
LRV S++ + NE + + ++E +L+ E K+++
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1648
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ Q +L V + +E I +E L+ E++ + +E+ E + + + +I
Sbjct: 1649 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
Query: 526 KLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E R++ + + ++++K+ A+ L + + +++E + +C ++
Sbjct: 1709 TSE-RVQLLHSQNTSLINQKKKMDAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++++ + A E M + ++ Q L+ AE A
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804
Score = 51.6 bits (118), Expect = 9e-06
Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + + D ++
Sbjct: 904 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKRDIDDLE 958
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 32.3 bits (70), Expect = 5.6
Identities = 52/240 (21%), Positives = 105/240 (43%), Gaps = 18/240 (7%)
Query: 402 GNYEQALRVKRSV---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
G++ Q R+ E Q+ +S+ +L + ++++ ++ K A + +
Sbjct: 716 GDFRQRYRILNPAAIPEGQFIDSRKGAEKL-LSSLDIDHNQYKFGHTKVFFKAGLLGLLE 774
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
E+R DER R+ T ++ + + + ++E KK LE + S+ + + A +
Sbjct: 775 EMR--DERLSRIITRIQA------QSRGVLARME-YKKLLE---RRDSLLVIQWNIRAFM 822
Query: 519 GGKRII-SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
G K KL +IK + + EK + + R KE K + E ++K +SLLQ
Sbjct: 823 GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ + Q V + LA+ E Q + + + +++ +R + E + + AK R
Sbjct: 883 EKNDLQLQ-VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKR 941
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1823
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1824 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1883
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1884 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1929
Score = 80.2 bits (189), Expect = 2e-14
Identities = 74/359 (20%), Positives = 183/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N + +AE + IK K+Q++ E++
Sbjct: 871 KELEEKMVSLLQEKNDLQLQVQAEQDN--LADAEERCDQ---LIKNKIQLEAKVKEMNER 925
Query: 343 VANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 926 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 985
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+
Sbjct: 986 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN-TLTKAKVKLEQQVDDLEGSLEQ-EKK 1043
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++ K + E+ ++ R+E+ +A
Sbjct: 1044 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQ 1103
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K+ + +L+ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 1104 LQKK-LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 1216
Score = 78.2 bits (184), Expect = 9e-14
Identities = 57/272 (20%), Positives = 131/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 860 KEALEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDL 1034
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D++ L + L+K +++
Sbjct: 1035 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ---LDERLKKKDFELNALN 1091
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Score = 74.5 bits (175), Expect = 1e-12
Identities = 82/352 (23%), Positives = 157/352 (44%), Gaps = 40/352 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +++++N R+ E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 914 QLEAKVKEMNERL-EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 357 KQSLQLTEIQTHYDEV-----------QRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE+ Q Q LD + ++ +LT +V+
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +V+ +E+ + + + ++L + K ++++ L D++
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLK--KKDFELNAL 1090
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRL 509
RI DE + Q+ EL+ +E L EE E K+E ++ L E++ IS RL
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 1151 EEA-GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH---ADSVAELGEQ 1206
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
N+ ++ LEK + S +K +L + +Q + ++ ED+
Sbjct: 1207 IDNLQRVKQKLEK---EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
Score = 72.1 bits (169), Expect = 6e-12
Identities = 80/355 (22%), Positives = 160/355 (45%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL +++AK+E+ + ++ +
Sbjct: 1091 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 1143
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A VQ E+ E ++ R + + +L+ E ++R + +
Sbjct: 1144 EEISERLEEAGGA-TSVQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 1198
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 1313
Score = 66.1 bits (154), Expect = 4e-10
Identities = 119/554 (21%), Positives = 234/554 (42%), Gaps = 44/554 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 1165 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 1218
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 1396
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 1457 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 1576 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV 650
R AE + + + ++ Q +L+ A D + N++++ ++ + V
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
Query: 651 YLVQESRALSSERL 664
+ SR L+ + L
Sbjct: 1693 EQTERSRKLAEQEL 1706
Score = 65.7 bits (153), Expect = 5e-10
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L E +E V+ + + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1478
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + I E+E++R E
Sbjct: 1479 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLE 1534
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 1535 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 1587
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1644
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 1645 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
Score = 58.8 bits (136), Expect = 6e-08
Identities = 88/461 (19%), Positives = 184/461 (39%), Gaps = 25/461 (5%)
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
AKA Q +L ++ V R RT + +K LA+ L E++ +
Sbjct: 1353 AKAELQRVLSKANSEVAQWRTKYETDAIQRT----EELEEAKKKLAQRLQEAEEAVEAVN 1408
Query: 238 RVTESITETVRVRETSPTTCVV---RINTELPAIDNSYLNQLNELKETVKQFDDLSVYIL 294
S+ +T + +V R N A+D N L E +++++ +
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + S+ E + E+ E R K LQ +I++L L + KT +L+K
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA-- 407
K+ + E+Q+ +E + L+ + AQ + E+E E EQA
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 408 --LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
LRV S++ + NE + + ++E +L+ E K+++
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1648
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ Q +L V + +E I +E L+ E++ + +E+ E + + + +I
Sbjct: 1649 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
Query: 526 KLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E R++ + + ++++K+ A+ L + + +++E + +C ++
Sbjct: 1709 TSE-RVQLLHSQNTSLINQKKKMDAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++++ + A E M + ++ Q L+ AE A
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804
Score = 51.6 bits (118), Expect = 9e-06
Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + + D ++
Sbjct: 904 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKRDIDDLE 958
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 32.3 bits (70), Expect = 5.6
Identities = 52/240 (21%), Positives = 105/240 (43%), Gaps = 18/240 (7%)
Query: 402 GNYEQALRVKRSV---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
G++ Q R+ E Q+ +S+ +L + ++++ ++ K A + +
Sbjct: 716 GDFRQRYRILNPAAIPEGQFIDSRKGAEKL-LSSLDIDHNQYKFGHTKVFFKAGLLGLLE 774
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
E+R DER R+ T ++ + + + ++E KK LE + S+ + + A +
Sbjct: 775 EMR--DERLSRIITRIQA------QSRGVLARME-YKKLLE---RRDSLLVIQWNIRAFM 822
Query: 519 GGKRII-SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
G K KL +IK + + EK + + R KE K + E ++K +SLLQ
Sbjct: 823 GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ + Q V + LA+ E Q + + + +++ +R + E + + AK R
Sbjct: 883 EKNDLQLQ-VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKR 941
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1823
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1824 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1883
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1884 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1929
Score = 80.2 bits (189), Expect = 2e-14
Identities = 74/359 (20%), Positives = 183/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N + +AE + IK K+Q++ E++
Sbjct: 871 KELEEKMVSLLQEKNDLQLQVQAEQDN--LADAEERCDQ---LIKNKIQLEAKVKEMNER 925
Query: 343 VANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 926 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 985
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+
Sbjct: 986 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN-TLTKAKVKLEQQVDDLEGSLEQ-EKK 1043
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++ K + E+ ++ R+E+ +A
Sbjct: 1044 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQ 1103
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K+ + +L+ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 1104 LQKK-LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 1216
Score = 78.2 bits (184), Expect = 9e-14
Identities = 57/272 (20%), Positives = 131/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 860 KEALEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDL 1034
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D++ L + L+K +++
Sbjct: 1035 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ---LDERLKKKDFELNALN 1091
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Score = 74.5 bits (175), Expect = 1e-12
Identities = 82/352 (23%), Positives = 157/352 (44%), Gaps = 40/352 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +++++N R+ E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 914 QLEAKVKEMNERL-EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 357 KQSLQLTEIQTHYDEV-----------QRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE+ Q Q LD + ++ +LT +V+
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +V+ +E+ + + + ++L + K ++++ L D++
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLK--KKDFELNAL 1090
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRL 509
RI DE + Q+ EL+ +E L EE E K+E ++ L E++ IS RL
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 1151 EEA-GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH---ADSVAELGEQ 1206
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
N+ ++ LEK + S +K +L + +Q + ++ ED+
Sbjct: 1207 IDNLQRVKQKLEK---EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
Score = 72.1 bits (169), Expect = 6e-12
Identities = 80/355 (22%), Positives = 160/355 (45%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL +++AK+E+ + ++ +
Sbjct: 1091 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 1143
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A VQ E+ E ++ R + + +L+ E ++R + +
Sbjct: 1144 EEISERLEEAGGA-TSVQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 1198
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 1313
Score = 66.1 bits (154), Expect = 4e-10
Identities = 119/554 (21%), Positives = 234/554 (42%), Gaps = 44/554 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 1165 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 1218
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 1396
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 1457 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 1576 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV 650
R AE + + + ++ Q +L+ A D + N++++ ++ + V
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
Query: 651 YLVQESRALSSERL 664
+ SR L+ + L
Sbjct: 1693 EQTERSRKLAEQEL 1706
Score = 65.7 bits (153), Expect = 5e-10
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L E +E V+ + + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1478
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + I E+E++R E
Sbjct: 1479 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLE 1534
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 1535 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 1587
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1644
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 1645 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
Score = 58.8 bits (136), Expect = 6e-08
Identities = 88/461 (19%), Positives = 184/461 (39%), Gaps = 25/461 (5%)
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
AKA Q +L ++ V R RT + +K LA+ L E++ +
Sbjct: 1353 AKAELQRVLSKANSEVAQWRTKYETDAIQRT----EELEEAKKKLAQRLQEAEEAVEAVN 1408
Query: 238 RVTESITETVRVRETSPTTCVV---RINTELPAIDNSYLNQLNELKETVKQFDDLSVYIL 294
S+ +T + +V R N A+D N L E +++++ +
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + S+ E + E+ E R K LQ +I++L L + KT +L+K
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA-- 407
K+ + E+Q+ +E + L+ + AQ + E+E E EQA
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 408 --LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
LRV S++ + NE + + ++E +L+ E K+++
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1648
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ Q +L V + +E I +E L+ E++ + +E+ E + + + +I
Sbjct: 1649 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
Query: 526 KLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E R++ + + ++++K+ A+ L + + +++E + +C ++
Sbjct: 1709 TSE-RVQLLHSQNTSLINQKKKMDAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++++ + A E M + ++ Q L+ AE A
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804
Score = 51.6 bits (118), Expect = 9e-06
Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + + D ++
Sbjct: 904 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKRDIDDLE 958
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 32.3 bits (70), Expect = 5.6
Identities = 52/240 (21%), Positives = 105/240 (43%), Gaps = 18/240 (7%)
Query: 402 GNYEQALRVKRSV---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
G++ Q R+ E Q+ +S+ +L + ++++ ++ K A + +
Sbjct: 716 GDFRQRYRILNPAAIPEGQFIDSRKGAEKL-LSSLDIDHNQYKFGHTKVFFKAGLLGLLE 774
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
E+R DER R+ T ++ + + + ++E KK LE + S+ + + A +
Sbjct: 775 EMR--DERLSRIITRIQA------QSRGVLARME-YKKLLE---RRDSLLVIQWNIRAFM 822
Query: 519 GGKRII-SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
G K KL +IK + + EK + + R KE K + E ++K +SLLQ
Sbjct: 823 GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ + Q V + LA+ E Q + + + +++ +R + E + + AK R
Sbjct: 883 EKNDLQLQ-VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKR 941
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 828 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 887
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 888 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 947
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 948 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 1007
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 1008 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1067
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1068 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1127
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1128 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1173
Score = 80.2 bits (189), Expect = 2e-14
Identities = 74/359 (20%), Positives = 183/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N + +AE + IK K+Q++ E++
Sbjct: 115 KELEEKMVSLLQEKNDLQLQVQAEQDN--LADAEERCDQ---LIKNKIQLEAKVKEMNER 169
Query: 343 VANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 170 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 229
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+
Sbjct: 230 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN-TLTKAKVKLEQQVDDLEGSLEQ-EKK 287
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++ K + E+ ++ R+E+ +A
Sbjct: 288 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQ 347
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K+ + +L+ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 348 LQKK-LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 406
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 407 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 460
Score = 78.2 bits (184), Expect = 9e-14
Identities = 57/272 (20%), Positives = 131/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 104 KEALEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 161
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 162 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 221
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 222 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDL 278
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D++ L + L+K +++
Sbjct: 279 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ---LDERLKKKDFELNALN 335
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 336 ARIEDEQALGSQLQKKLKELQARIEELEEELE 367
Score = 74.5 bits (175), Expect = 1e-12
Identities = 82/352 (23%), Positives = 157/352 (44%), Gaps = 40/352 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +++++N R+ E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 158 QLEAKVKEMNERL-EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 216
Query: 357 KQSLQLTEIQTHYDEV-----------QRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE+ Q Q LD + ++ +LT +V+
Sbjct: 217 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 276
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +V+ +E+ + + + ++L + K ++++ L D++
Sbjct: 277 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLK--KKDFELNAL 334
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRL 509
RI DE + Q+ EL+ +E L EE E K+E ++ L E++ IS RL
Sbjct: 335 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 394
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 395 EEA-GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH---ADSVAELGEQ 450
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
N+ ++ LEK + S +K +L + +Q + ++ ED+
Sbjct: 451 IDNLQRVKQKLEK---EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 499
Score = 72.1 bits (169), Expect = 6e-12
Identities = 80/355 (22%), Positives = 160/355 (45%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 217 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 274
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 275 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 334
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL +++AK+E+ + ++ +
Sbjct: 335 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 387
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A VQ E+ E ++ R + + +L+ E ++R + +
Sbjct: 388 EEISERLEEAGGA-TSVQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 442
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 443 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 502
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 503 HRSKAEETQRSVNDLTSQQAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 557
Score = 66.1 bits (154), Expect = 4e-10
Identities = 119/554 (21%), Positives = 234/554 (42%), Gaps = 44/554 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 409 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 462
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 463 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQQ 521
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 522 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 581
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 582 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 640
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 641 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 700
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 701 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 759
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 760 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 819
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 820 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 876
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV 650
R AE + + + ++ Q +L+ A D + N++++ ++ + V
Sbjct: 877 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 936
Query: 651 YLVQESRALSSERL 664
+ SR L+ + L
Sbjct: 937 EQTERSRKLAEQEL 950
Score = 65.7 bits (153), Expect = 5e-10
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L E +E V+ + + +
Sbjct: 603 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 662
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 663 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 722
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + I E+E++R E
Sbjct: 723 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLE 778
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 779 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 831
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++
Sbjct: 832 RNHLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 888
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 889 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 947
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 948 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 996
Score = 58.8 bits (136), Expect = 6e-08
Identities = 88/461 (19%), Positives = 184/461 (39%), Gaps = 25/461 (5%)
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
AKA Q +L ++ V R RT + +K LA+ L E++ +
Sbjct: 597 AKAELQRVLSKANSEVAQWRTKYETDAIQRT----EELEEAKKKLAQRLQEAEEAVEAVN 652
Query: 238 RVTESITETVRVRETSPTTCVV---RINTELPAIDNSYLNQLNELKETVKQFDDLSVYIL 294
S+ +T + +V R N A+D N L E +++++ +
Sbjct: 653 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 712
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + S+ E + E+ E R K LQ +I++L L + KT +L+K
Sbjct: 713 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 772
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA-- 407
K+ + E+Q+ +E + L+ + AQ + E+E E EQA
Sbjct: 773 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 832
Query: 408 --LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
LRV S++ + NE + + ++E +L+ E K+++
Sbjct: 833 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 892
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ Q +L V + +E I +E L+ E++ + +E+ E + + + +I
Sbjct: 893 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 952
Query: 526 KLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E R++ + + ++++K+ A+ L + + +++E + +C ++
Sbjct: 953 TSE-RVQLLHSQNTSLINQKKKMDAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAA 1007
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++++ + A E M + ++ Q L+ AE A
Sbjct: 1008 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1048
Score = 51.6 bits (118), Expect = 9e-06
Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 88 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 147
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + + D ++
Sbjct: 148 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKRDIDDLE 202
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 203 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 250
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1823
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1824 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1883
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1884 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1929
Score = 79.4 bits (187), Expect = 4e-14
Identities = 74/359 (20%), Positives = 182/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N + +AE + IK K+Q++ E++
Sbjct: 871 KELEEKMVSLLQEKNDLQLQVQAEQDN--LADAEERCDQ---LIKNKIQLEAKVKEMNER 925
Query: 343 VANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 926 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 985
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+
Sbjct: 986 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN-TLTKAKVKLEQQVDDLEGSLEQ-EKK 1043
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++ K + E+ ++ R+E+ +A
Sbjct: 1044 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQ 1103
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K+ + +L+ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S +
Sbjct: 1104 LQKK-LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIE 1162
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 1216
Score = 78.2 bits (184), Expect = 9e-14
Identities = 57/272 (20%), Positives = 131/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 860 KEALEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDL 1034
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D++ L + L+K +++
Sbjct: 1035 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ---LDERLKKKDFELNALN 1091
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 1092 ARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Score = 74.5 bits (175), Expect = 1e-12
Identities = 82/352 (23%), Positives = 157/352 (44%), Gaps = 40/352 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +++++N R+ E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 914 QLEAKVKEMNERL-EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 357 KQSLQLTEIQTHYDEV-----------QRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE+ Q Q LD + ++ +LT +V+
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +V+ +E+ + + + ++L + K ++++ L D++
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLK--KKDFELNAL 1090
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRL 509
RI DE + Q+ EL+ +E L EE E K+E ++ L E++ IS RL
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 1151 EEA-GGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH---ADSVAELGEQ 1206
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
N+ ++ LEK + S +K +L + +Q + ++ ED+
Sbjct: 1207 IDNLQRVKQKLEK---EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
Score = 70.1 bits (164), Expect = 2e-11
Identities = 79/355 (22%), Positives = 159/355 (44%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL +++AK+E+ + ++ +
Sbjct: 1091 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 1143
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A Q E+ E ++ R + + +L+ E ++R + +
Sbjct: 1144 EEISERLEEAGGA-TSCQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 1198
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 1313
Score = 66.1 bits (154), Expect = 4e-10
Identities = 119/554 (21%), Positives = 234/554 (42%), Gaps = 44/554 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 1165 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 1218
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 1396
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 1457 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 1576 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV 650
R AE + + + ++ Q +L+ A D + N++++ ++ + V
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
Query: 651 YLVQESRALSSERL 664
+ SR L+ + L
Sbjct: 1693 EQTERSRKLAEQEL 1706
Score = 65.7 bits (153), Expect = 5e-10
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L E +E V+ + + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1478
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + I E+E++R E
Sbjct: 1479 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLE 1534
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 1535 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 1587
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1644
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 1645 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 1704 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
Score = 58.8 bits (136), Expect = 6e-08
Identities = 88/461 (19%), Positives = 184/461 (39%), Gaps = 25/461 (5%)
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
AKA Q +L ++ V R RT + +K LA+ L E++ +
Sbjct: 1353 AKAELQRVLSKANSEVAQWRTKYETDAIQRT----EELEEAKKKLAQRLQEAEEAVEAVN 1408
Query: 238 RVTESITETVRVRETSPTTCVV---RINTELPAIDNSYLNQLNELKETVKQFDDLSVYIL 294
S+ +T + +V R N A+D N L E +++++ +
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + S+ E + E+ E R K LQ +I++L L + KT +L+K
Sbjct: 1469 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA-- 407
K+ + E+Q+ +E + L+ + AQ + E+E E EQA
Sbjct: 1529 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Query: 408 --LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
LRV S++ + NE + + ++E +L+ E K+++
Sbjct: 1589 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1648
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ Q +L V + +E I +E L+ E++ + +E+ E + + + +I
Sbjct: 1649 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1708
Query: 526 KLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E R++ + + ++++K+ A+ L + + +++E + +C ++
Sbjct: 1709 TSE-RVQLLHSQNTSLINQKKKMDAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAA 1763
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++++ + A E M + ++ Q L+ AE A
Sbjct: 1764 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804
Score = 51.6 bits (118), Expect = 9e-06
Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + + D ++
Sbjct: 904 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKRDIDDLE 958
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
Score = 32.3 bits (70), Expect = 5.6
Identities = 52/240 (21%), Positives = 105/240 (43%), Gaps = 18/240 (7%)
Query: 402 GNYEQALRVKRSV---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
G++ Q R+ E Q+ +S+ +L + ++++ ++ K A + +
Sbjct: 716 GDFRQRYRILNPAAIPEGQFIDSRKGAEKL-LSSLDIDHNQYKFGHTKVFFKAGLLGLLE 774
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
E+R DER R+ T ++ + + + ++E KK LE + S+ + + A +
Sbjct: 775 EMR--DERLSRIITRIQA------QSRGVLARME-YKKLLE---RRDSLLVIQWNIRAFM 822
Query: 519 GGKRII-SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
G K KL +IK + + EK + + R KE K + E ++K +SLLQ
Sbjct: 823 GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 882
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ + Q V + LA+ E Q + + + +++ +R + E + + AK R
Sbjct: 883 EKNDLQLQ-VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKR 941
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 233 bits (569), Expect = 2e-60
Identities = 119/346 (34%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 1223 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1282
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ E
Sbjct: 1283 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1342
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 1343 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 1402
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 1403 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1462
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1463 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1522
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1523 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1568
Score = 80.2 bits (189), Expect = 2e-14
Identities = 74/359 (20%), Positives = 183/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N + +AE + IK K+Q++ E++
Sbjct: 510 KELEEKMVSLLQEKNDLQLQVQAEQDN--LADAEERCDQ---LIKNKIQLEAKVKEMNER 564
Query: 343 VANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 565 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 624
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+
Sbjct: 625 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN-TLTKAKVKLEQQVDDLEGSLEQ-EKK 682
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++ K + E+ ++ R+E+ +A
Sbjct: 683 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQ 742
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K+ + +L+ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 743 LQKK-LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 801
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 802 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 855
Score = 78.2 bits (184), Expect = 9e-14
Identities = 57/272 (20%), Positives = 131/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 499 KEALEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 556
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 557 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 616
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 617 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDL 673
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D++ L + L+K +++
Sbjct: 674 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ---LDERLKKKDFELNALN 730
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 731 ARIEDEQALGSQLQKKLKELQARIEELEEELE 762
Score = 74.5 bits (175), Expect = 1e-12
Identities = 82/352 (23%), Positives = 157/352 (44%), Gaps = 40/352 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +++++N R+ E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 553 QLEAKVKEMNERL-EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 611
Query: 357 KQSLQLTEIQTHYDEV-----------QRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE+ Q Q LD + ++ +LT +V+
Sbjct: 612 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 671
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +V+ +E+ + + + ++L + K ++++ L D++
Sbjct: 672 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLK--KKDFELNAL 729
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRL 509
RI DE + Q+ EL+ +E L EE E K+E ++ L E++ IS RL
Sbjct: 730 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 789
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 790 EEA-GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH---ADSVAELGEQ 845
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
N+ ++ LEK + S +K +L + +Q + ++ ED+
Sbjct: 846 IDNLQRVKQKLEK---EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 894
Score = 72.1 bits (169), Expect = 6e-12
Identities = 80/355 (22%), Positives = 160/355 (45%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 612 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 669
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 670 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 729
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL +++AK+E+ + ++ +
Sbjct: 730 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 782
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A VQ E+ E ++ R + + +L+ E ++R + +
Sbjct: 783 EEISERLEEAGGA-TSVQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 837
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 838 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 897
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 898 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 952
Score = 66.1 bits (154), Expect = 4e-10
Identities = 119/554 (21%), Positives = 234/554 (42%), Gaps = 44/554 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 804 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 857
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 858 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 916
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 917 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 976
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 977 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 1035
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 1036 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1095
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 1096 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1154
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 1155 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1214
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 1215 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1271
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV 650
R AE + + + ++ Q +L+ A D + N++++ ++ + V
Sbjct: 1272 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1331
Query: 651 YLVQESRALSSERL 664
+ SR L+ + L
Sbjct: 1332 EQTERSRKLAEQEL 1345
Score = 65.7 bits (153), Expect = 5e-10
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L E +E V+ + + +
Sbjct: 998 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1057
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 1058 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 1117
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + I E+E++R E
Sbjct: 1118 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLE 1173
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 1174 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 1226
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++
Sbjct: 1227 RNHLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 1283
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L +
Sbjct: 1284 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1342
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 1343 QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1391
Score = 58.8 bits (136), Expect = 6e-08
Identities = 88/461 (19%), Positives = 184/461 (39%), Gaps = 25/461 (5%)
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
AKA Q +L ++ V R RT + +K LA+ L E++ +
Sbjct: 992 AKAELQRVLSKANSEVAQWRTKYETDAIQRT----EELEEAKKKLAQRLQEAEEAVEAVN 1047
Query: 238 RVTESITETVRVRETSPTTCVV---RINTELPAIDNSYLNQLNELKETVKQFDDLSVYIL 294
S+ +T + +V R N A+D N L E +++++ +
Sbjct: 1048 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1107
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + S+ E + E+ E R K LQ +I++L L + KT +L+K
Sbjct: 1108 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1167
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA-- 407
K+ + E+Q+ +E + L+ + AQ + E+E E EQA
Sbjct: 1168 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1227
Query: 408 --LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
LRV S++ + NE + + ++E +L+ E K+++
Sbjct: 1228 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 1287
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ Q +L V + +E I +E L+ E++ + +E+ E + + + +I
Sbjct: 1288 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIE 1347
Query: 526 KLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E R++ + + ++++K+ A+ L + + +++E + +C ++
Sbjct: 1348 TSE-RVQLLHSQNTSLINQKKKMDAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAA 1402
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++++ + A E M + ++ Q L+ AE A
Sbjct: 1403 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1443
Score = 51.6 bits (118), Expect = 9e-06
Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 483 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 542
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + + D ++
Sbjct: 543 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKRDIDDLE 597
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 598 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 645
Score = 32.3 bits (70), Expect = 5.6
Identities = 52/240 (21%), Positives = 105/240 (43%), Gaps = 18/240 (7%)
Query: 402 GNYEQALRVKRSV---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
G++ Q R+ E Q+ +S+ +L + ++++ ++ K A + +
Sbjct: 355 GDFRQRYRILNPAAIPEGQFIDSRKGAEKL-LSSLDIDHNQYKFGHTKVFFKAGLLGLLE 413
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
E+R DER R+ T ++ + + + ++E KK LE + S+ + + A +
Sbjct: 414 EMR--DERLSRIITRIQA------QSRGVLARME-YKKLLE---RRDSLLVIQWNIRAFM 461
Query: 519 GGKRII-SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
G K KL +IK + + EK + + R KE K + E ++K +SLLQ
Sbjct: 462 GVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQ 521
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ + Q V + LA+ E Q + + + +++ +R + E + + AK R
Sbjct: 522 EKNDLQLQ-VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKR 580
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 232 bits (567), Expect = 3e-60
Identities = 117/342 (34%), Positives = 205/342 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
D K+ + + + ++AE + +++ RIKKK++ + E+E+ L+ AN+ + + +
Sbjct: 1588 DQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNL 1647
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ L + Q H D+ R +Q + +RR + EVEE+R + E+ R ++ E
Sbjct: 1648 RNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAE 1707
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ ++ RV L N +L ++K K+E +++ + + ++I +E R A+E+ ++ T+
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAA 1767
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E VK++ +RL E E A+ GGK+ I KLEAR++++E
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELE 1827
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
E++ E++ + E +K LRK ER++KE+ Q EED+KNI LQD ++K KV YKRQ
Sbjct: 1828 SEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAE 1887
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E S ++ + R+ Q ELE AE+RAD+AES ++ +R K R
Sbjct: 1888 EAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1929
Score = 91.9 bits (218), Expect = 7e-18
Identities = 75/373 (20%), Positives = 177/373 (47%), Gaps = 18/373 (4%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ + ++ V +K S + + K++LQ ++ +L + ++ +N I L K
Sbjct: 1390 LEEAKKKLAQRLQDAEEHVEAVNSKCAS-LEKTKQRLQNEVEDLMIDVERSNAACIALDK 1448
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L E + Y+E Q +L+ + Q+ +SL+ E+ +++ YE++L +
Sbjct: 1449 KQRNFDKVLAEWKQKYEETQAELEAS-------QKESRSLSTELFKVKNAYEESLDHLET 1501
Query: 414 VEQQYEESQTRVNELTVINVN-------LSSSKAKIEQELAIVAADYDEITKELRIADER 466
++++ + Q +++LT L K +++ E + + +E L + +
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGK 1561
Query: 467 YQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
R+Q EL + + E+ +++ +K++ V+++ L+ E + RI
Sbjct: 1562 ILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLD-AEIRSRNDALRIKK 1620
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K+E + +ME++L+ R+ AE ++ LR + LK+ + ++ + L++ L +
Sbjct: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTST 644
+ ++ + ++ E +++ + ++EL A +R + + N SLI K + S
Sbjct: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
Query: 645 VPGSQVYLVQESR 657
+ G +VQE+R
Sbjct: 1741 IQGEMEDIVQEAR 1753
Score = 88.2 bits (209), Expect = 8e-17
Identities = 60/302 (19%), Positives = 143/302 (47%), Gaps = 6/302 (1%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K ++++ +K +L + + E++ ++ + + Q
Sbjct: 835 KLYFKIKPLLKSAET-EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL 893
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++Q+ + + +Q ++ K +E + +E R + IN L++ K K+E E +
Sbjct: 894 QVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 953
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNI-S 506
+ D D++ L ++ + ++K+ E + E I K+ KK+L E + +
Sbjct: 954 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1013
Query: 507 VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQC 566
+++EE + N + K +KLE ++ D+E L++EK+ + + RK E LK
Sbjct: 1014 LQMEEDKVNTLTKAK---TKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQEST 1070
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
+ + + L + L+K ++S + ++ +++ ++ Q +++ Q +E E+ +
Sbjct: 1071 MDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAER 1130
Query: 627 SN 628
++
Sbjct: 1131 AS 1132
Score = 74.9 bits (176), Expect = 8e-13
Identities = 81/417 (19%), Positives = 178/417 (42%), Gaps = 18/417 (4%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITE 245
++E ++E + A + + + + L K++ L +K + TE+ +
Sbjct: 923 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK--EKHATENKVK 980
Query: 246 TVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEI 305
+ + ++ E A+ ++ L++L Q ++ V L + + ++
Sbjct: 981 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL-----QMEEDKVNTLTKAKTKLEQQV 1035
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQIT-ELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+ L + E E KL ++ R K+KL+ + E ++D N L + +KK+ +++
Sbjct: 1036 DDLEGSL-EQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQ-QLNEKLKKKEFEMSN 1093
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+Q ++ Q + Q RI+ L E+E R + +A + + + ++ EE R
Sbjct: 1094 LQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER 1153
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEIT--KELRIADERYQRVQT--ELKHTVEH 480
+ E K E E + D +E T E A R + + EL ++
Sbjct: 1154 LEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQIDS 1213
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDE 540
L ++ K+E K L++E+ +++ +E V + A +++ LE ++ +++ + +E
Sbjct: 1214 LQRVKQ---KLEKEKSELKMEINDLASNMETV-SKAKANFEKMCRTLEDQLSEIKTKEEE 1269
Query: 541 EKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
++R E + + E Q +E +S L + +Q++ KRQL E+
Sbjct: 1270 QQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEE 1326
Score = 74.5 bits (175), Expect = 1e-12
Identities = 63/315 (20%), Positives = 154/315 (48%), Gaps = 10/315 (3%)
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ--LTEIQTHYDEVQRQLQVTLDQY 383
IK K+Q++ E++ ++ I+ + T KK+ L+ +E++ D+++ L +
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKI 442
+ ++++LT E+ + + + K+++++ ++++ + E +N L+ +K K+
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNT-LTKAKTKL 1031
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
EQ++ + ++ K + ++++ +LK E + + ++ K E E+
Sbjct: 1032 EQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEM 1091
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
N+ ++E+ +A A+ K+I +L+ARI+++E E++ E+ A+ K R+L+E+
Sbjct: 1092 SNLQGKIEDEQALAMQLQKKI-KELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEI 1150
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
+ EE S + +K + +R L E + + +R+ + A+ A
Sbjct: 1151 SERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRK-----KHADSVA 1205
Query: 623 DVAESNLSLIRAKHR 637
++ + SL R K +
Sbjct: 1206 ELGKQIDSLQRVKQK 1220
Score = 69.3 bits (162), Expect = 4e-11
Identities = 101/499 (20%), Positives = 202/499 (40%), Gaps = 32/499 (6%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL E + + AA R K A ++A E + + + + K
Sbjct: 1169 KKREAEFQKMRRDLEESTL----QHEATAAALRKKHADSVA-----ELGKQIDSLQRVKQ 1219
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
+ ++ + + +L+ N+ + + ++KA R E ++ +E R+
Sbjct: 1220 KLEKEKSELKMEINDLASNM--ETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQ----RL 1273
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS 321
EL A + E + + D + V L+ + + +IE+L R +E ETK KS
Sbjct: 1274 INELSAQKARLHTESGEFSRQLDEKDAM-VSQLSRGKQAFTQQIEELK-RQLEEETKAKS 1331
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY--DEVQRQLQVT 379
+ + + L + + +LQ+ + K + ++ + +T Y D +QR ++
Sbjct: 1332 TLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELE 1391
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ +AQR +Q VE + + K+ ++ + E+ V + L +
Sbjct: 1392 EAKKKLAQR-LQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQ 1450
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
++ LA Y+E EL + + + + TEL E + + ++ K+L+
Sbjct: 1451 RNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQ 1510
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
E+ +++ ++ E GGK I +LE K ++ E E + E L +E ++
Sbjct: 1511 QEISDLTEQIAE-------GGKH-IHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKI 1562
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ IQ E +Q + + EK + + + L E M +R L +
Sbjct: 1563 --LRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
Query: 620 D-RADVAESNLSLIRAKHR 637
D+ E + L A +
Sbjct: 1621 KMEGDLNEMEIQLNHANRQ 1639
Score = 66.5 bits (155), Expect = 3e-10
Identities = 85/498 (17%), Positives = 210/498 (42%), Gaps = 20/498 (4%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
K Q+++ E+E L +L + G A T+ E+ + NE++ K +F
Sbjct: 1030 KLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEF 1089
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKA-MNSCDSRV-TESITETVRVRETSPTTC-VVR 260
+ S + L K + E +A + + + E + ++ S + +
Sbjct: 1090 EMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
Query: 261 INTELPAIDNSYLNQLNELKETVKQFD----DLSVYILNDSSKQTSIEIEQLNA-----R 311
I+ L + Q+ K+ +F DL L + ++ + ++ +
Sbjct: 1150 ISERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGK 1209
Query: 312 VVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
+++ ++K ++ + K +L+++I +L +++ +K + +K + QL+EI+T +E
Sbjct: 1210 QIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEE 1269
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
QR + Q + +++E Q R K++ QQ EE + ++ E T
Sbjct: 1270 QQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKA 1329
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL-KHTVEHLHEEQERIVK 490
L+ + + ++ Y+E + + +E+ + ++ + +R +
Sbjct: 1330 KSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEE 1389
Query: 491 IEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK 550
+E KK L +++ +E V + ++ +L+ ++D+ ++++ R +A I
Sbjct: 1390 LEEAKKKLAQRLQDAEEHVEAVNSKC-ASLEKTKQRLQNEVEDLMIDVE---RSNAACI- 1444
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS--IYKRQLAEQEGMSQQSVTRV 608
L KK+R +V+ + ++ + ++ +K S+ +S ++K + A +E + +
Sbjct: 1445 ALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKR 1504
Query: 609 RRFQRELEAAEDRADVAE 626
+ E ++ +AE
Sbjct: 1505 ENKNLQQEISDLTEQIAE 1522
Score = 51.2 bits (117), Expect = 1e-05
Identities = 69/371 (18%), Positives = 150/371 (40%), Gaps = 27/371 (7%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
V R N A+D N L E +++++ + + S+ E + E+
Sbjct: 1436 VERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEES 1495
Query: 318 KLKSE-VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
E + R K LQ +I++L + K +L+K K+ + +E+QT +E + L
Sbjct: 1496 LDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASL 1555
Query: 377 ----------QVTLDQY-GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRV 425
Q+ L+Q R+I E+++++ N+ LRV S++ +
Sbjct: 1556 EHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNH---LRVVESMQSTLDAEIRSR 1612
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
N+ I + ++E +L E + LR + Q L + + +
Sbjct: 1613 NDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLK 1672
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
E++ +E ++ EV+ + LE E + + ++ E R++ + H
Sbjct: 1673 EQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASE-RVQLL----------H 1721
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
+ ++ K ++L+ I Q + + ++I + E+ ++K +AE+ Q +
Sbjct: 1722 TQNTSLINTK-KKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1780
Query: 606 TRVRRFQRELE 616
+ R ++ +E
Sbjct: 1781 AHLERMKKNME 1791
Score = 33.1 bits (72), Expect = 3.2
Identities = 52/289 (17%), Positives = 119/289 (41%), Gaps = 8/289 (2%)
Query: 144 KRMQEIEKELDLYEKEVNLGSE-LRQKAAMY--RGKSAKAIAQTLLEESRRNVQNERMYK 200
+ Q I K+ L+ + G + L+++ AM R +A + L R + +M +
Sbjct: 1648 RNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAE 1707
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALME---SKAMNSCDSRVTESITETVRVRETSPTTC 257
+ + V +T + + K +E S+ + V E+ + ++
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAA 1767
Query: 258 VVRINTELPAIDNSYLNQLNE-LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
++ + +++L ++ + +++TVK + K +I++L ARV E E
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELE 1827
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
++++SE + ++ ++ +T D + ++ Q L + ++QT +RQ
Sbjct: 1828 SEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDL-VDKLQTKVKAYKRQA 1886
Query: 377 QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRV 425
+ +Q V + + L E+EE + A + + E T+V
Sbjct: 1887 EEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1935
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 231 bits (565), Expect = 6e-60
Identities = 118/342 (34%), Positives = 205/342 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
D K+ + + ++AE + +++ R+KKK++ + E+E+ L+ AN+ + +
Sbjct: 1587 DQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNY 1646
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ L E Q H D+ R + +Q + +RR L E+EE+ EQ R ++ E
Sbjct: 1647 RNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAE 1706
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ ++ RV L N +L ++K K+E +++ + ++ +E+ +E R A+E+ ++ T+
Sbjct: 1707 QELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAA 1766
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK+LE VK++ RL+E E A+ GGK+ I KLEAR++++E
Sbjct: 1767 MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE 1826
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
E++ E++R+AE +K LRK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1827 GEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E S ++++ R+ Q ELE AE+RA +AES ++ +R K R
Sbjct: 1887 EAEEQSNANLSKFRKLQHELEEAEERAHIAESQVNKLRVKSR 1928
Score = 90.6 bits (215), Expect = 2e-17
Identities = 78/373 (20%), Positives = 174/373 (46%), Gaps = 18/373 (4%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ + +++ V K S + + K++LQ ++ +L L ++ +N L K
Sbjct: 1389 LEEAKKKLAQRLQEAEEHVEAVNAKCAS-LEKTKQRLQNEVEDLMLDVERSNAACAALDK 1447
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L+E + Y+E Q +L+ +Q+ +SL+ E+ +++ YE++L +
Sbjct: 1448 KQRNFDKVLSEWKQKYEETQAELE-------ASQKESRSLSTELFKVKNVYEESLDQLET 1500
Query: 414 VEQQYEESQTRVNELTVINV-------NLSSSKAKIEQELAIVAADYDEITKELRIADER 466
+ ++ + Q +++LT L K ++EQE + A +E L + +
Sbjct: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
Query: 467 YQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
R+Q EL + + E+ +I+ +K++ V+ + L + E + R+
Sbjct: 1561 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTL-DAEIRSRNDALRVKK 1619
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K+E + +ME++L+ R AE+++ R + LKE + ++ + L++ L +
Sbjct: 1620 KMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVER 1679
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTST 644
+ ++ + ++ E +Q+ + ++EL A +R + + N SLI K + S
Sbjct: 1680 RANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQ 1739
Query: 645 VPGSQVYLVQESR 657
+ ++QESR
Sbjct: 1740 LQSEVEEVIQESR 1752
Score = 84.6 bits (200), Expect = 1e-15
Identities = 64/290 (22%), Positives = 134/290 (46%), Gaps = 6/290 (2%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
KL +I L S + K +++ +K +L + + E++ ++ L + Q
Sbjct: 834 KLFFKIKPLLKSAET-EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQL 892
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++QS + + EQ ++ K +E + +E R E IN L++ K K+E E +
Sbjct: 893 QVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 952
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNI-S 506
+ D D++ L ++ + ++K+ E + E I K+ KK+L E + +
Sbjct: 953 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDD 1012
Query: 507 VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQC 566
++ EE + N + K +KLE ++ D+E L++EK+ + + RK E LK
Sbjct: 1013 LQAEEDKVNILTKAK---TKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQEST 1069
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ + + L + LEK ++S ++ +++ + Q +++ Q +E
Sbjct: 1070 MDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIE 1119
Score = 78.2 bits (184), Expect = 9e-14
Identities = 100/496 (20%), Positives = 225/496 (45%), Gaps = 29/496 (5%)
Query: 147 QEIEKELDLYEKEV-NLGSELRQKAAM--YRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
Q+++++L+ E E+ NL S++ + A+ K K + Q +EE ++ ER +
Sbjct: 1077 QQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKEL-QARIEELGEEIEAERASRAKA 1135
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
+ R+ ++R+ +S+ L +A + A + + E+ + +R R+ T ++
Sbjct: 1136 EKQRSDLSRELEEISER-LEEAGGATSAQVELNKK-REAEFQKLR-RDLEEAT--LQHEA 1190
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+ A+ + + + EL E + + + + S + +E + L++ EA +K K +
Sbjct: 1191 MVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKS-ELKMETDDLSSNA-EAISKAKGNL 1248
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++ + L+ Q++EL+ + + Q+ I + Q +QT E RQL
Sbjct: 1249 EKMCRSLEDQVSELKTKEE-------EQQRLINDLTAQRARLQTEAGEYSRQLDEKDALV 1301
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
R Q+ T ++EE++ E+ + K ++ + S+ + L KA+++
Sbjct: 1302 SQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQ 1361
Query: 444 QELAIVAADYDE-ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
+ L+ ++ + TK A +R + ++ K + L E +E + + A SLE
Sbjct: 1362 RALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTK 1421
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET---IKILRKKERQL 559
+ + +E++ + + + L+ + ++ + L E K+++ ET ++ +K+ R L
Sbjct: 1422 QRLQNEVEDLMLD-VERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSL 1480
Query: 560 KEVIIQC----EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ + EE + L+ + Q++S Q+AE G + ++++ Q E
Sbjct: 1481 STELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE-GGKQIHELEKIKK-QVEQ 1538
Query: 616 EAAEDRADVAESNLSL 631
E E +A + E+ SL
Sbjct: 1539 EKCEIQAALEEAEASL 1554
Score = 77.4 bits (182), Expect = 2e-13
Identities = 72/358 (20%), Positives = 177/358 (49%), Gaps = 16/358 (4%)
Query: 284 KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDV 343
K+ ++ V +L + + ++++ + +AE + + IK K+Q++ E++
Sbjct: 874 KELEEKMVTLLKEKN-DLQLQVQSEADSLADAEERCEQ---LIKNKIQLEAKIKEVTERA 929
Query: 344 ANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
+ I+ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 930 EEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 989
Query: 402 GNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKEL 460
+ + K+++++ ++++ + E +N+ L+ +K K+EQ++ + ++ K+L
Sbjct: 990 ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI-LTKAKTKLEQQVDDLEGSLEQ-EKKL 1047
Query: 461 RIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
R+ ER +R ++ +LK E + + +++ + E E+ N+ ++E+ +A I
Sbjct: 1048 RMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQL 1107
Query: 520 GKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS 579
K+ I +L+ARI+++ E++ E+ A+ K R+L+E+ + EE S +
Sbjct: 1108 QKK-IKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVEL 1166
Query: 580 LEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + V +R+ + A+ A++ E +L R K +
Sbjct: 1167 NKKREAEFQKLRRDLEEATLQHEAMVAALRK-----KHADSMAELGEQIDNLQRVKQK 1219
Score = 70.9 bits (166), Expect = 1e-11
Identities = 79/341 (23%), Positives = 161/341 (47%), Gaps = 27/341 (7%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSI-EIEQLNARVVEAETKLKSEVTRIKKKLQIQIT 335
N++K ++ L I S ++ ++ E Q ++AE + +T+ K KL+ Q+
Sbjct: 976 NKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVD 1035
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+LE SL+ K +DL++ +K L Q +++ Q ++ + I +L
Sbjct: 1036 DLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLIS 1095
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
++E+ EQA+ ++ ++++ +E Q R+ EL +S+AK E++ + ++ + +E
Sbjct: 1096 KIED-----EQAVEIQ--LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 1148
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN 515
I++ L A Q EL E ++ R + + +L+ E ++R + ++
Sbjct: 1149 ISERLEEAGGA-TSAQVELNKKREAEFQKLRR----DLEEATLQHEAMVAALRKKHADSM 1203
Query: 516 AIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI--------KILRKKERQLKEV 562
A +G +R+ KLE ++++E D + +AE I K+ R E Q+ E+
Sbjct: 1204 AELGEQIDNLQRVKQKLEKEKSELKMETD-DLSSNAEAISKAKGNLEKMCRSLEDQVSEL 1262
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+ EE Q+ I+ L + + Y RQL E++ + Q
Sbjct: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQ 1303
Score = 70.1 bits (164), Expect = 2e-11
Identities = 66/340 (19%), Positives = 162/340 (47%), Gaps = 15/340 (4%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +I+++ R E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 917 QLEAKIKEVTERA-EEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 975
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG-EVEEIRGNYEQALRVKRSVE 415
+ LTE DE +L + ++ + + Q+L + EE + N + K +E
Sbjct: 976 NKVKNLTEEMAGLDETIAKL--SKEKKALQETHQQTLDDLQAEEDKVNI--LTKAKTKLE 1031
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
QQ ++ + + + + ++L +K K+E +L + ++ + + DE+ ++ + E+
Sbjct: 1032 QQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEIS 1091
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
+ + + +EQ ++++ K L+ ++ + +E A+ K+ S L ++++
Sbjct: 1092 NLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ-RSDLSRELEEIS 1150
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
L+E + +++ +K+E + +++ EE + +L K K + +L
Sbjct: 1151 ERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK---KHADSMAELG 1207
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAK 635
EQ Q+ ++ + + EL+ D D++ + ++ +AK
Sbjct: 1208 EQIDNLQRVKQKLEKEKSELKMETD--DLSSNAEAISKAK 1245
Score = 60.5 bits (140), Expect = 2e-08
Identities = 96/507 (18%), Positives = 215/507 (42%), Gaps = 50/507 (9%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
K+++++ + EL + +++ +E KA K +++ + E + + +R+ D
Sbjct: 1217 KQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLIN-D 1275
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
A R + + S+ + K + S+ S + T+ I E E +
Sbjct: 1276 LTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQAS-TQQIEELKHQLEEE-----TKAK 1329
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
L S + + L+E ++ + + SK S E+ Q + + E
Sbjct: 1330 NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS-EVAQWRTKYETDAIQRTEE 1388
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ KKKL ++ E E ++ N L+KT KQ LQ +EV+ + LD
Sbjct: 1389 LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKT--KQRLQ--------NEVE---DLMLDV 1435
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
R + +++ + N+++ L +Q+YEE+Q + + +LS+ K+
Sbjct: 1436 -----ERSNAACAALDKKQRNFDKVLS---EWKQKYEETQAELEASQKESRSLSTELFKV 1487
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
+ Y+E +L + +Q E+ E + E ++I ++E +KK +E E
Sbjct: 1488 KNV-------YEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEK 1540
Query: 503 KNISVRLEEVEAN-AIVGGK---------RIISKLEARIKDMELELDEEKRRHAETIKIL 552
I LEE EA+ GK ++ S+++ +I + + E+D+ KR H ++ +
Sbjct: 1541 CEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETM 1600
Query: 553 RK----KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
+ + R + + ++ + +++ ++ L ++ + R +G+ +++ +
Sbjct: 1601 QSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHL 1660
Query: 609 RRFQRELEAAEDRADVAESNLSLIRAK 635
R E +++ + E +L++A+
Sbjct: 1661 DDALRGQEDLKEQLAIVERRANLLQAE 1687
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/250 (19%), Positives = 114/250 (45%), Gaps = 24/250 (9%)
Query: 275 QLNELKETVKQFD---DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ EL T++Q + ++ L D+S++ + + N ++ + KL+++V++++ +++
Sbjct: 1687 EIEELWATLEQTERSRKIAEQELLDASERVQL-LHTQNTSLINTKKKLENDVSQLQSEVE 1745
Query: 332 IQITELELSLDVANKTNID---LQKTIKKQ---SLQLTEIQTHYDEVQRQLQVTLDQYGV 385
I E + + A K D + + +KK+ S L ++ + ++ + LQ LD+
Sbjct: 1746 EVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1805
Query: 386 -----AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN-------V 433
+++IQ L V E+ G E + + + + RV ELT +
Sbjct: 1806 LALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVL 1865
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
L K++ ++ +E ++ +++++Q EL+ E H + ++ K+
Sbjct: 1866 RLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERAHIAESQVNKLRV 1925
Query: 494 VKKSLEIEVK 503
KS E+ K
Sbjct: 1926 --KSREVHTK 1933
>M25142-1|AAA60387.1| 389|Homo sapiens myosin heavy chain
alpha-subunit protein.
Length = 389
Score = 231 bits (565), Expect = 6e-60
Identities = 117/325 (36%), Positives = 201/325 (61%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
++AET+ ++EV R+KKK++ + E+E+ L AN+ + QK +K L + Q D+
Sbjct: 53 LDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 112
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
R + + +RR L E+EE+R EQ R ++ +++ E+ RV L N
Sbjct: 113 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQN 172
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
+L + K K+E +L + ++ +E +E R A+E+ ++ T+ E L +EQ+ +E
Sbjct: 173 TSLINQKKKMEADLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 232
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
+KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E EL+ E++R+AE++K +
Sbjct: 233 RMKKNIEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 292
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQ 612
RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ E E + ++++ R+ Q
Sbjct: 293 RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 352
Query: 613 RELEAAEDRADVAESNLSLIRAKHR 637
EL+ AE+RAD+AES ++ +RAK R
Sbjct: 353 HELDEAEERADIAESQVNKLRAKSR 377
Score = 51.2 bits (117), Expect = 1e-05
Identities = 51/300 (17%), Positives = 140/300 (46%), Gaps = 19/300 (6%)
Query: 345 NKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI----QSLTGEVEEI 400
N+ ++++ + ++ ++ + + ++ V LQ +LD ++ + + + G++ E+
Sbjct: 18 NQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEM 77
Query: 401 RGNYEQALRVK-------RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
A R+ +S++ +++Q ++++ N +L + A +E+ ++ A+
Sbjct: 78 EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL 137
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+E+ + + + EL T E + + + KK +E ++ + +EE
Sbjct: 138 EELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMEADLTQLQSEVEEAV 197
Query: 514 ---ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-D 569
NA K+ I+ +A + EL+ +++ H E +K + E+ +K++ + +E +
Sbjct: 198 QECRNAEEKAKKAIT--DAAMMAEELKKEQDTSAHLERMK--KNIEQTIKDLQHRLDEAE 253
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
Q + + L+K +V + +L ++ + +SV +R+ +R ++ + + + NL
Sbjct: 254 QIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNL 313
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (1151
AA) protein.
Length = 1151
Score = 230 bits (563), Expect = 1e-59
Identities = 117/346 (33%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 800 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 859
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ +
Sbjct: 860 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAD 919
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
++ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 920 EELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 979
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 980 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1039
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1040 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1099
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1100 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1145
Score = 81.4 bits (192), Expect = 9e-15
Identities = 75/359 (20%), Positives = 183/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N + +AE + IK K+Q++ E++
Sbjct: 87 KELEEKMVSLLQEKNDLQLQVQAEQDN--LADAEERCDQ---LIKNKIQLEAKVKEMNER 141
Query: 343 VANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L + +E++ D+++ L + + ++++LT E+ +
Sbjct: 142 LEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 201
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N L+ +K K+EQ++ + ++ K+
Sbjct: 202 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN-TLTKAKVKLEQQVDDLEGSLEQ-EKK 259
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + ++E K + E+ ++ R+E+ +A
Sbjct: 260 VRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQ 319
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K+ + +L+ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 320 LQKK-LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 378
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 379 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 432
Score = 79.0 bits (186), Expect = 5e-14
Identities = 57/272 (20%), Positives = 132/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 76 KEALEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 133
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 134 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 193
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 194 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDL 250
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D++ L++ L+K +++
Sbjct: 251 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ---LEERLKKKDFELNALN 307
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ + Q +++ Q +E E+ +
Sbjct: 308 ARIEDEQALGSQLQKKLKELQARIEELEEELE 339
Score = 75.8 bits (178), Expect = 5e-13
Identities = 83/352 (23%), Positives = 157/352 (44%), Gaps = 40/352 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK---TIK 356
Q +++++N R+ E E ++ +E+T K+KL+ + +EL+ +D T ++K +
Sbjct: 130 QLEAKVKEMNERL-EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 188
Query: 357 KQSLQLTEIQTHYDEV-----------QRQLQVTLDQYGVAQRRIQSLT-------GEVE 398
+ LTE DE+ Q Q LD + ++ +LT +V+
Sbjct: 189 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 248
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++ G+ EQ +V+ +E+ + + + ++L + K ++E+ L D++
Sbjct: 249 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLK--KKDFELNAL 306
Query: 459 ELRIADE-----RYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRL 509
RI DE + Q+ EL+ +E L EE E K+E ++ L E++ IS RL
Sbjct: 307 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 366
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
EE A + K EA + M +L+E +H T LRKK + + + E
Sbjct: 367 EEA-GGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH---ADSVAELGEQ 422
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
N+ ++ LEK + S +K +L + +Q + ++ ED+
Sbjct: 423 IDNLQRVKQKLEK---EKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 471
Score = 72.5 bits (170), Expect = 4e-12
Identities = 80/355 (22%), Positives = 160/355 (45%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 189 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 246
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 247 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNAL 306
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL +++AK+E+ + ++ +
Sbjct: 307 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 359
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A VQ E+ E ++ R + + +L+ E ++R + +
Sbjct: 360 EEISERLEEAGGA-TSVQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 414
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 415 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 474
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 475 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 529
Score = 67.3 bits (157), Expect = 2e-10
Identities = 120/554 (21%), Positives = 234/554 (42%), Gaps = 44/554 (7%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 381 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 434
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 435 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 493
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 494 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 553
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 554 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 612
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 613 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 672
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 673 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 731
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 732 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 791
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 792 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 848
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV 650
R AE + + + ++ Q +L+ A D + N++++ ++ + V
Sbjct: 849 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 908
Query: 651 YLVQESRALSSERL 664
+ SR L+ E L
Sbjct: 909 EQTERSRKLADEEL 922
Score = 65.7 bits (153), Expect = 5e-10
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 238 RVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD------DLSV 291
RV V T T ++ EL +L E +E V+ + + +
Sbjct: 575 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 634
Query: 292 YILNDSSKQTSIEIEQLNARVVEAETKLKSE---VTRIKKKLQIQITELELSLDVANKTN 348
+ L + + +++E+ NA + K ++ + K+K + +ELE S A +
Sbjct: 635 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLS 694
Query: 349 IDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE 405
+L K L ++T E +Q ++ +Q G + + I E+E++R E
Sbjct: 695 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLE 750
Query: 406 -QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + ++ ++E+ + ++ + + KA+IE++LA E +E+ A
Sbjct: 751 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA-------EKDEEMEQAK 803
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ RV L+ +++ + ++ VKK +E ++ + ++L A K++
Sbjct: 804 RNHLRVVDSLQTSLDAETRSRNEALR---VKKKMEGDLNEMEIQLSHANRMAAEAQKQVK 860
Query: 525 SKLEARIKDMELELDEEKRRH---AETIKILRKK----ERQLKEVIIQCEEDQKNISLLQ 577
S L++ +KD +++LD+ R + E I I+ ++ + +L+E+ E+ +++ L
Sbjct: 861 S-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAD 919
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
+ L +TS++V + Q ++ + + Q E+E A AE
Sbjct: 920 EELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 968
Score = 59.3 bits (137), Expect = 4e-08
Identities = 88/461 (19%), Positives = 184/461 (39%), Gaps = 25/461 (5%)
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
AKA Q +L ++ V R RT + +K LA+ L E++ +
Sbjct: 569 AKAELQRVLSKANSEVAQWRTKYETDAIQRT----EELEEAKKKLAQRLQEAEEAVEAVN 624
Query: 238 RVTESITETVRVRETSPTTCVV---RINTELPAIDNSYLNQLNELKETVKQFDDLSVYIL 294
S+ +T + +V R N A+D N L E +++++ +
Sbjct: 625 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 684
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + S+ E + E+ E R K LQ +I++L L + KT +L+K
Sbjct: 685 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 744
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQA-- 407
K+ + E+Q+ +E + L+ + AQ + E+E E EQA
Sbjct: 745 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 804
Query: 408 --LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
LRV S++ + NE + + ++E +L+ E K+++
Sbjct: 805 NHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQS 864
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ Q +L V + +E I +E L+ E++ + +E+ E + + + +I
Sbjct: 865 LLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADEELIE 924
Query: 526 KLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
E R++ + + ++++K+ A+ L + + +++E + +C ++
Sbjct: 925 TSE-RVQLLHSQNTSLINQKKKMDAD----LSQLQTEVEEAVQECRNAEEKAKKAITDAA 979
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++++ + A E M + ++ Q L+ AE A
Sbjct: 980 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1020
Score = 51.6 bits (118), Expect = 9e-06
Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 60 EREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 119
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + + D ++
Sbjct: 120 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKRDIDDLE 174
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 175 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 222
>X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (
544 AA) protein.
Length = 543
Score = 230 bits (562), Expect = 1e-59
Identities = 117/346 (33%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 192 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 251
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ +
Sbjct: 252 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAD 311
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
++ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 312 RELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 371
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 372 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 431
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 432 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 491
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 492 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 537
Score = 76.2 bits (179), Expect = 4e-13
Identities = 76/355 (21%), Positives = 159/355 (44%), Gaps = 19/355 (5%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
VEA S + + K +LQ +I +L + ++ +N L K + L E + Y+E
Sbjct: 12 VEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEES 71
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT--- 429
Q +L+ +Q+ +SL+ E+ +++ YE++L + +++ + Q +++LT
Sbjct: 72 QSELE-------SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQL 124
Query: 430 -----VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
I+ L + ++E E + + +E L + + R Q E + +
Sbjct: 125 GSSGKTIH-ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 183
Query: 485 -QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
E+ ++E K++ V ++ L + E + R+ K+E + +ME++L R
Sbjct: 184 LAEKDEEMEQAKRNHLRVVDSLQTSL-DAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 242
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
AE K ++ + LK+ IQ ++ + L++++ ++ ++ + +L E + +Q
Sbjct: 243 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 302
Query: 604 SVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTSTVPGSQVYLVQESR 657
+ + REL +R + S N SLI K + S + VQE R
Sbjct: 303 TERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECR 357
Score = 53.6 bits (123), Expect = 2e-06
Identities = 58/305 (19%), Positives = 131/305 (42%), Gaps = 23/305 (7%)
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
++ + +LQ ++ V R + +++ + N+++ L +Q+YEESQ+ +
Sbjct: 23 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA---EWKQKYEESQSELESSQ 79
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
+LS+ K++ Y+E + L + +Q E+ E L + I
Sbjct: 80 KEARSLSTELFKLKNA-------YEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH 132
Query: 490 KIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEARIKDMELELD 539
++E V+K LE E + LEE EA+ A + +I +++E ++ + + E++
Sbjct: 133 ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 192
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+ KR H ++++ + L E + ++ L + ++S R AE +
Sbjct: 193 QAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQK 249
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRAL 659
+ + ++ Q +L+ A D + N++++ ++ + V + SR L
Sbjct: 250 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 309
Query: 660 SSERL 664
+ L
Sbjct: 310 ADREL 314
Score = 44.8 bits (101), Expect = 0.001
Identities = 50/272 (18%), Positives = 107/272 (39%), Gaps = 4/272 (1%)
Query: 388 RRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA 447
+R+Q VE + + K ++ + E+ V L + ++ LA
Sbjct: 3 QRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA 62
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
Y+E EL + + + + TEL E E + + K+L+ E+ +++
Sbjct: 63 EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE 122
Query: 508 RLEEVEANAIVGGKRIISKLEARIKDMELELDE-EKRRHAETIKILRKKERQLKEVIIQC 566
+L I +++ +LEA +++ L+E E E KILR + + ++ +
Sbjct: 123 QLGS-SGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR-AQLEFNQIKAEI 180
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
E + ++ +V + + E S+ RV++ + E + E ++
Sbjct: 181 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKK-KMEGDLNEMEIQLSH 239
Query: 627 SNLSLIRAKHRTFVTTSTVPGSQVYLVQESRA 658
+N A+ + S + +Q+ L RA
Sbjct: 240 ANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 271
>M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain
beta-subunit protein.
Length = 611
Score = 230 bits (562), Expect = 1e-59
Identities = 117/346 (33%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 260 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 319
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ +
Sbjct: 320 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAD 379
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
++ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 380 RELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 439
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 440 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 499
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 500 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 559
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 560 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 605
Score = 77.8 bits (183), Expect = 1e-13
Identities = 78/374 (20%), Positives = 168/374 (44%), Gaps = 20/374 (5%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L ++ K+ + +++ VEA S + + K +LQ +I +L + ++ +N L K
Sbjct: 62 LEEAKKKLAQRLQEAE-EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDK 120
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ L E + Y+E Q +L+ +Q+ +SL+ E+ +++ YE++L +
Sbjct: 121 KQRNFDKILAEWKQKYEESQSELE-------SSQKEARSLSTELFKLKNAYEESLEHLET 173
Query: 414 VEQQYEESQTRVNELT--------VINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
+++ + Q +++LT I+ L + ++E E + + +E L +
Sbjct: 174 FKRENKNLQEEISDLTEQLGSSGKTIH-ELEKVRKQLEAEKMELQSALEEAEASLEHEEG 232
Query: 466 RYQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
+ R Q E + + E+ ++E K++ V ++ L + E + R+
Sbjct: 233 KILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL-DAETRSRNEALRVK 291
Query: 525 SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS 584
K+E + +ME++L R AE K ++ + LK+ IQ ++ + L++++
Sbjct: 292 KKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVE 351
Query: 585 QKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTS 643
++ ++ + +L E + +Q+ + REL +R + S N SLI K + S
Sbjct: 352 RRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLS 411
Query: 644 TVPGSQVYLVQESR 657
+ VQE R
Sbjct: 412 QLQTEVEEAVQECR 425
Score = 61.7 bits (143), Expect = 8e-09
Identities = 70/364 (19%), Positives = 153/364 (42%), Gaps = 18/364 (4%)
Query: 314 EAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +L E + +
Sbjct: 24 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQRLQEAEEAVEA 82
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
V + Q I+ L +VE + +R+ ++ E + + E +
Sbjct: 83 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE-SQS 141
Query: 432 NVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
+ S +A+ + EL + Y+E + L + +Q E+ E L + I +
Sbjct: 142 ELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHE 201
Query: 491 IEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEARIKDMELELDE 540
+E V+K LE E + LEE EA+ A + +I +++E ++ + + E+++
Sbjct: 202 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 261
Query: 541 EKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM 600
KR H ++++ + L E + ++ L + ++S R AE +
Sbjct: 262 AKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 318
Query: 601 SQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALS 660
+ + ++ Q +L+ A D + N++++ ++ + V + SR L+
Sbjct: 319 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 378
Query: 661 SERL 664
L
Sbjct: 379 DREL 382
>M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac
myosin heavy chain mRNA, 3' end. ).
Length = 543
Score = 230 bits (562), Expect = 1e-59
Identities = 117/346 (33%), Positives = 207/346 (59%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 192 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 251
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR L E+EE+R EQ R ++ +
Sbjct: 252 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAD 311
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
++ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 312 RELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 371
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 372 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 431
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 432 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 491
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 492 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 537
Score = 76.2 bits (179), Expect = 4e-13
Identities = 76/355 (21%), Positives = 159/355 (44%), Gaps = 19/355 (5%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
VEA S + + K +LQ +I +L + ++ +N L K + L E + Y+E
Sbjct: 12 VEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEES 71
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT--- 429
Q +L+ +Q+ +SL+ E+ +++ YE++L + +++ + Q +++LT
Sbjct: 72 QSELE-------SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQL 124
Query: 430 -----VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
I+ L + ++E E + + +E L + + R Q E + +
Sbjct: 125 GSSGKTIH-ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 183
Query: 485 -QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
E+ ++E K++ V ++ L + E + R+ K+E + +ME++L R
Sbjct: 184 LAEKDEEMEQAKRNHLRVVDSLQTSL-DAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 242
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
AE K ++ + LK+ IQ ++ + L++++ ++ ++ + +L E + +Q
Sbjct: 243 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 302
Query: 604 SVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTSTVPGSQVYLVQESR 657
+ + REL +R + S N SLI K + S + VQE R
Sbjct: 303 TERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECR 357
Score = 53.6 bits (123), Expect = 2e-06
Identities = 58/305 (19%), Positives = 131/305 (42%), Gaps = 23/305 (7%)
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
++ + +LQ ++ V R + +++ + N+++ L +Q+YEESQ+ +
Sbjct: 23 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA---EWKQKYEESQSELESSQ 79
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
+LS+ K++ Y+E + L + +Q E+ E L + I
Sbjct: 80 KEARSLSTELFKLKNA-------YEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH 132
Query: 490 KIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEARIKDMELELD 539
++E V+K LE E + LEE EA+ A + +I +++E ++ + + E++
Sbjct: 133 ELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEME 192
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+ KR H ++++ + L E + ++ L + ++S R AE +
Sbjct: 193 QAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQK 249
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRAL 659
+ + ++ Q +L+ A D + N++++ ++ + V + SR L
Sbjct: 250 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 309
Query: 660 SSERL 664
+ L
Sbjct: 310 ADREL 314
Score = 44.8 bits (101), Expect = 0.001
Identities = 50/272 (18%), Positives = 107/272 (39%), Gaps = 4/272 (1%)
Query: 388 RRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA 447
+R+Q VE + + K ++ + E+ V L + ++ LA
Sbjct: 3 QRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA 62
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
Y+E EL + + + + TEL E E + + K+L+ E+ +++
Sbjct: 63 EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE 122
Query: 508 RLEEVEANAIVGGKRIISKLEARIKDMELELDE-EKRRHAETIKILRKKERQLKEVIIQC 566
+L I +++ +LEA +++ L+E E E KILR + + ++ +
Sbjct: 123 QLGS-SGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR-AQLEFNQIKAEI 180
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
E + ++ +V + + E S+ RV++ + E + E ++
Sbjct: 181 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKK-KMEGDLNEMEIQLSH 239
Query: 627 SNLSLIRAKHRTFVTTSTVPGSQVYLVQESRA 658
+N A+ + S + +Q+ L RA
Sbjct: 240 ANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 271
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 229 bits (561), Expect = 2e-59
Identities = 116/325 (35%), Positives = 201/325 (61%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
++AET+ ++EV R+KKK++ + E+E+ L AN+ + QK +K L + Q D+
Sbjct: 1603 LDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1662
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
R + + +RR L E+EE+R EQ R ++ +++ E+ RV L N
Sbjct: 1663 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQN 1722
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
+L + K K++ +L+ + ++ +E +E R A+E+ ++ T E L +EQ+ +E
Sbjct: 1723 TSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLE 1782
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
+KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E EL+ E++R+AE++K +
Sbjct: 1783 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQ 612
RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ E E + ++++ R+ Q
Sbjct: 1843 RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1902
Query: 613 RELEAAEDRADVAESNLSLIRAKHR 637
EL+ AE+RAD+AES ++ +RAK R
Sbjct: 1903 HELDEAEERADIAESQVNKLRAKSR 1927
Score = 81.0 bits (191), Expect = 1e-14
Identities = 75/359 (20%), Positives = 182/359 (50%), Gaps = 18/359 (5%)
Query: 284 KQFDDLSVYILNDSSK-QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
K+ ++ V +L + + Q ++ EQ N +AE + IK K+Q++ E++
Sbjct: 873 KELEEKMVSLLQEKNDLQLQVQAEQDNLN--DAEERCDQ---LIKNKIQLEAKVKEMNER 927
Query: 343 VANKTNIDLQKTIKKQSLQ--LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI 400
+ ++ ++ + T KK+ L+ +E++ D+++ L + + ++++LT E+ +
Sbjct: 928 LEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 987
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ + K+++++ ++++ + E +N LS SK K+EQ++ + ++ K+
Sbjct: 988 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT-LSKSKVKLEQQVDDLEGSLEQ-EKK 1045
Query: 460 LRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+R+ ER +R ++ +LK T E + + + +++E K E ++ + ++E+ + A+
Sbjct: 1046 VRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQ 1105
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K++ + +ARI+++E EL+ E+ A+ K+ R+L+E+ + EE S+ +
Sbjct: 1106 LQKKL-KENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+K + +R L E + + +R+ + A+ A++ E +L R K +
Sbjct: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRK-----KHADSVAELGEQIDNLQRVKQK 1218
Score = 74.1 bits (174), Expect = 1e-12
Identities = 57/272 (20%), Positives = 131/272 (48%), Gaps = 13/272 (4%)
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
K++L+ +E + E++ ++ L + Q ++Q+ + + +Q ++ K +E
Sbjct: 862 KETLEKSEARRK--ELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEA 919
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ +E R+ + +N L++ K K+E E + + D D++ L ++ + ++K+
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDM 534
E + E I K+ KK+L+ + ++ EE + N + K KLE ++ D+
Sbjct: 980 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLSKSK---VKLEQQVDDL 1036
Query: 535 ELELDEEKRRHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E L++EK+ + + RK E LK E I+ E D+ L++ L+K ++
Sbjct: 1037 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQ---LEEKLKKKEFDINQQN 1093
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
++ +++ ++ Q +++ Q +E E+ +
Sbjct: 1094 SKIEDEQVLALQLQKKLKENQARIEELEEELE 1125
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/493 (19%), Positives = 217/493 (44%), Gaps = 47/493 (9%)
Query: 148 EIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQ----NERMYKPDF 203
E EKE+ ++E E +K+ R + + + L E++ +Q + + +
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNS---CDSRVTESITETVRVRETSPTTCVVR 260
+ + + N+ + + L + + MN+ R E ++ + +
Sbjct: 906 RCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAK 965
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
+ E A +N N L E + D++ + + K+ E Q ++AE
Sbjct: 966 VEKEKHATENKVKN----LTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKV 1019
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS--LQLTE---IQTHYDEVQRQ 375
+ +++ K KL+ Q+ +LE SL+ K +DL++ +K L+LT+ + D++Q +
Sbjct: 1020 NTLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLE 1079
Query: 376 LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
++ ++ + Q+ ++E+ EQ L ++ ++++ +E+Q R+ EL
Sbjct: 1080 EKLKKKEFDINQQN-----SKIED-----EQVLALQ--LQKKLKENQARIEELEEELEAE 1127
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+++AK+E+ + ++ + +EI++ L A VQ E+ E ++ R ++ +
Sbjct: 1128 RTARAKVEKLRSDLSRELEEISERLEEAGGATS-VQIEMNKKREAEFQKMRRDLE----E 1182
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGK-----RIISKLEARIKDMELELDEEKRRHAETIK 550
+L+ E ++R + ++ A +G + R+ KLE + +LELD+ + IK
Sbjct: 1183 ATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK 1242
Query: 551 -------ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+ R E Q E ++ EE Q++++ K + RQL E+E + Q
Sbjct: 1243 AKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEKEALISQ 1302
Query: 604 SVTRVRRFQRELE 616
+ +++E
Sbjct: 1303 LTRGKLSYTQQME 1315
Score = 64.1 bits (149), Expect = 2e-09
Identities = 76/406 (18%), Positives = 171/406 (42%), Gaps = 18/406 (4%)
Query: 271 SYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL 330
SY Q+ +LK +++ + + L + + + + L + E ET+ K+E+ R+ K
Sbjct: 1309 SYTQQMEDLKRQLEE-EGKAKNALAHALQSARHDCDLLREQY-EEETEAKAELQRVLSKA 1366
Query: 331 QIQITELELSLDV-ANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
++ + + A + +L++ KK + +L + + + V + Q
Sbjct: 1367 NSEVAQCRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNE 1426
Query: 390 IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK-IEQELAI 448
I+ L +VE + +R+ ++ E + + E + + S +A+ + EL
Sbjct: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE-SQSELESSQKEARSLSTELFK 1485
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVR 508
+ Y+E + L + +Q E+ E L E + + ++E V+K LE+E +
Sbjct: 1486 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545
Query: 509 LEEVEAN----------AIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
LEE EA+ A + +I +++E ++ + + E+++ KR H + L +
Sbjct: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSL---QTS 1602
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
L E + ++ L + ++S R AE + + + ++ Q +L+ A
Sbjct: 1603 LDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1662
Query: 619 EDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
D + N++++ ++ + V + SR L+ L
Sbjct: 1663 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADREL 1708
Score = 58.8 bits (136), Expect = 6e-08
Identities = 100/519 (19%), Positives = 215/519 (41%), Gaps = 42/519 (8%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
KK + ++E L EKE + +E + K I L +E + + + D
Sbjct: 953 KKDIDDLELTLAKVEKEKH-ATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDD 1011
Query: 203 FQASRTLVN---RDYTNLSKNV--LAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
QA VN + L + V L +L + K + R + +++ + S
Sbjct: 1012 LQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES---- 1067
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILN--DSSKQTSIEIEQLNARVVEA 315
++ + + ++ + ++ + + +D V L K+ IE+L + EA
Sbjct: 1068 IMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEEL-EA 1126
Query: 316 ETKLKSEVTRIKKKLQIQITELELSLDVAN-KTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
E +++V +++ L ++ E+ L+ A T++ ++ K+++ + +++R
Sbjct: 1127 ERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA--------EFQKMRR 1178
Query: 375 QLQ-VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
L+ TL A + V E+ + RVK+ +E++ E + ++++T
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNME 1238
Query: 434 NLSSSKA---KIEQELAIVAADY----DEITKELRIADERYQRVQTELKHTVEHLHEEQE 486
+ +KA K+ + L A +Y +E + L + ++QTE L E++
Sbjct: 1239 QIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEKEA 1298
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMEL---ELDEEKR 543
I ++ K S +++++ +LEE E A + L++ D +L + +EE
Sbjct: 1299 LISQLTRGKLSYTQQMEDLKRQLEE-EGKA---KNALAHALQSARHDCDLLREQYEEETE 1354
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQ-KNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
AE ++L K ++ + + E D + L+++ +K +Q++ + +
Sbjct: 1355 AKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCS 1414
Query: 603 QSVTRVRRFQRELEAAEDRADVAESN--LSLIRAKHRTF 639
R Q E+E + DV SN + + K R F
Sbjct: 1415 SLEKTKHRLQNEIE--DLMVDVERSNAAAAALDKKQRNF 1451
Score = 58.0 bits (134), Expect = 1e-07
Identities = 70/378 (18%), Positives = 159/378 (42%), Gaps = 18/378 (4%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
V R N A+D N L E +++++ + + + S+ E + E+
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1493
Query: 318 KLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
E R K LQ +I++L L K +L+K K+ ++ E+Q+ +E + L
Sbjct: 1494 LEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASL 1553
Query: 377 QVTLDQYGVAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
+ + AQ + E+E ++ E+ + KR+ ++ + QT ++ T +
Sbjct: 1554 EHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEV 1613
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE-------QERI 488
K K+E +L + + A ++ + +Q+ LK T L + +E I
Sbjct: 1614 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENI 1673
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE----LDEEKRR 544
+E L+ E++ + +E+ E + + + +I E R++ + + ++++K+
Sbjct: 1674 AIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSE-RVQLLHSQNTSLINQKKKM 1732
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
A+ L + + +++E + +C ++ ++++ + A E M +
Sbjct: 1733 DAD----LSQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLERMKKNM 1788
Query: 605 VTRVRRFQRELEAAEDRA 622
++ Q L+ AE A
Sbjct: 1789 EQTIKDLQHRLDEAEQIA 1806
Score = 54.0 bits (124), Expect = 2e-06
Identities = 38/168 (22%), Positives = 82/168 (48%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + R++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEE 905
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R+L++ + ++D ++
Sbjct: 906 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRKLEDECSELKKDIDDLE 960
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1008
>M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myosin
heavy chain mRNA, 3' end. ).
Length = 532
Score = 229 bits (560), Expect = 2e-59
Identities = 117/325 (36%), Positives = 200/325 (61%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
++AET+ ++EV R+KKK++ + E+E+ L AN+ + QK +K L + Q D+
Sbjct: 197 LDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 256
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
R + + +RR L E+EE+R EQ R ++ EQ+ E+ RV L N
Sbjct: 257 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 316
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
+L + K K++ +L+ + ++ +E +E R A+E+ ++ T+ E L +EQ+ +E
Sbjct: 317 TSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 376
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
+KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E EL+ E++R+AE++K +
Sbjct: 377 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 436
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQ 612
RK ER++KE+ Q EED+KN+ LQD + K KV YK Q E E + ++++ R+ Q
Sbjct: 437 RKSERRIKELTYQTEEDKKNLLRLQDLVNKLQLKVKAYKGQAEEAEERANTNLSKFRKVQ 496
Query: 613 RELEAAEDRADVAESNLSLIRAKHR 637
EL+ AE+RAD+AES ++ +RAK R
Sbjct: 497 HELDEAEERADIAESQVNKLRAKSR 521
Score = 66.9 bits (156), Expect = 2e-10
Identities = 75/369 (20%), Positives = 169/369 (45%), Gaps = 36/369 (9%)
Query: 270 NSYLNQLNELKETVK-QFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKK 328
N+ + L + K ++ + +DL V + ++ +++ +Q N + AE K K E ++
Sbjct: 4 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ--- 60
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE---VQRQLQVTLDQYGV 385
+ELE S A + +L K L ++T E +Q ++ +Q G
Sbjct: 61 ------SELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGE 114
Query: 386 AQRRIQSLTGEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQ 444
+ + E+E++R E + + ++ ++E+ + ++ + + KA+IE+
Sbjct: 115 GGKNVH----ELEKVRNQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER 170
Query: 445 ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKN 504
+A E +E+ A +QRV L+ +++ + +++ VKK +E ++
Sbjct: 171 NVA-------EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLR---VKKKMEGDLNE 220
Query: 505 ISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH---AETIKILRKK----ER 557
+ ++L A K++ S L++ +KD +++LD+ R + E I I+ ++ +
Sbjct: 221 MEIQLSHANRMAAEAQKQVKS-LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 279
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
+L+E+ E+ +++ L + L +TS++V + Q ++ + + Q E+E
Sbjct: 280 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEE 339
Query: 618 AEDRADVAE 626
A AE
Sbjct: 340 AVQECRNAE 348
Score = 58.4 bits (135), Expect = 8e-08
Identities = 69/366 (18%), Positives = 165/366 (45%), Gaps = 18/366 (4%)
Query: 274 NQLNELKETVKQFDD--LSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRI-KKKL 330
N E+ + +Q + +V+ L Q +E +L + + EAE L+ E +I + +L
Sbjct: 100 NLQEEISDLTEQLGEGGKNVHELEKVRNQLEVEKMELQSALEEAEASLEHEEGKILRAQL 159
Query: 331 QIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI 390
+ + E+ +VA K ++++ + + +QT D R L + +
Sbjct: 160 EFNQIKAEIERNVAEKDE-EMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDL 218
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVA 450
+ ++ +A + +S++ +++Q ++++ N +L + A +E+ ++
Sbjct: 219 NEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQ 278
Query: 451 ADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLE 510
A+ +E LR E+ +R + K + L E ER+ + + SL + K + L
Sbjct: 279 AELEE----LRAVVEQTERSR---KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLS 331
Query: 511 EVEA---NAIVGGKRIISKLEARIKD---MELELDEEKRRHAETIKILRKKERQLKEVII 564
++++ A+ + K + I D M EL +E+ A ++ + E+ +K++
Sbjct: 332 QLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH 391
Query: 565 QCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
+ +E +Q + + L+K +V + +L ++ + +SV +R+ +R ++ + +
Sbjct: 392 RLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTE 451
Query: 624 VAESNL 629
+ NL
Sbjct: 452 EDKKNL 457
Score = 55.6 bits (128), Expect = 5e-07
Identities = 69/378 (18%), Positives = 157/378 (41%), Gaps = 18/378 (4%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
V R N A+D N L E +++++ + + + S+ E + E+
Sbjct: 28 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 87
Query: 318 KLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
E R K LQ +I++L L K +L+K + ++ E+Q+ +E + L
Sbjct: 88 LEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRNQLEVEKMELQSALEEAEASL 147
Query: 377 QVTLDQYGVAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
+ + AQ + E+E + E+ + KR+ ++ + QT ++ T +
Sbjct: 148 EHEEGKILRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEV 207
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE-------QERI 488
K K+E +L + + A ++ + +Q+ LK T L + +E I
Sbjct: 208 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENI 267
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE----LDEEKRR 544
+E L+ E++ + +E+ E + + + +I E R++ + + ++++K+
Sbjct: 268 AIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE-RVQLLHSQNTSLINQKKKM 326
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
A+ L + + +++E + +C ++ ++++ + A E M +
Sbjct: 327 DAD----LSQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM 382
Query: 605 VTRVRRFQRELEAAEDRA 622
++ Q L+ AE A
Sbjct: 383 EQTIKDLQHRLDEAEQIA 400
Score = 54.0 bits (124), Expect = 2e-06
Identities = 58/305 (19%), Positives = 130/305 (42%), Gaps = 23/305 (7%)
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
++ + +LQ ++ V R + +++ + N+++ L +Q+YEESQ+ +
Sbjct: 11 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA---EWKQKYEESQSELESSQ 67
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
+LS+ K++ Y+E + L + +Q E+ E L E + +
Sbjct: 68 KEARSLSTELFKLKNA-------YEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVH 120
Query: 490 KIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEARIKDMELELD 539
++E V+ LE+E + LEE EA+ A + +I +++E + + + E++
Sbjct: 121 ELEKVRNQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEEME 180
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+ KR H + L + L E + ++ L + ++S R AE +
Sbjct: 181 QAKRNHQRVVDSL---QTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQK 237
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRAL 659
+ + ++ Q +L+ A D + N++++ ++ + V + SR L
Sbjct: 238 QVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKL 297
Query: 660 SSERL 664
+ + L
Sbjct: 298 AEQEL 302
Score = 45.6 bits (103), Expect = 6e-04
Identities = 49/262 (18%), Positives = 107/262 (40%), Gaps = 4/262 (1%)
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
E + + K ++ + E+ V L + ++ LA Y+E
Sbjct: 1 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 60
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
EL + + + + TEL E E + + K+L+ E+ +++ +L E N +
Sbjct: 61 SELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKN-V 119
Query: 518 VGGKRIISKLEARIKDMELELDE-EKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLL 576
+++ ++LE +++ L+E E E KILR + + ++ + E +
Sbjct: 120 HELEKVRNQLEVEKMELQSALEEAEASLEHEEGKILR-AQLEFNQIKAEIERNVAEKDEE 178
Query: 577 QDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
+ ++ Q+V + + E S+ V RV++ + E + E ++ +N A+
Sbjct: 179 MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKK-KMEGDLNEMEIQLSHANRMAAEAQK 237
Query: 637 RTFVTTSTVPGSQVYLVQESRA 658
+ S + +Q+ L RA
Sbjct: 238 QVKSLQSLLKDTQIQLDDAVRA 259
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 228 bits (557), Expect = 6e-59
Identities = 117/346 (33%), Positives = 208/346 (60%), Gaps = 1/346 (0%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +K+ + + ++AET+ ++E R+KKK++ + E+E+ L AN+ + QK +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L + Q D+ R + + +RR +L E+EE+R EQ R ++ +
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERR-NNLQAELEELRAVVEQTERSRKLAD 1702
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
++ E+ RV L N +L + K K++ +L+ + + +E +E R A+E+ ++ T+
Sbjct: 1703 RELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAA 1762
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E L +EQ+ +E +KK++E +K++ RL+E E A+ GGK+ + KLEAR++++E
Sbjct: 1763 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELE 1822
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
EL+ E++R+AE++K +RK ER++KE+ Q EED+KN+ LQD ++K KV YKRQ
Sbjct: 1823 NELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAE 1882
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 1883 EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 1928
Score = 70.1 bits (164), Expect = 2e-11
Identities = 79/355 (22%), Positives = 159/355 (44%), Gaps = 26/355 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N++ L E + D++ + + K+ E Q ++AE + +T+ K KL+ Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ +LE SL+ K +DL++ +K L Q +++ Q ++ + +L
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E+ EQAL ++++ +E Q R+ EL +++AK+E+ + ++ +
Sbjct: 1091 NARIED-----EQAL--GSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 1143
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+EI++ L A Q E+ E ++ R + + +L+ E ++R + +
Sbjct: 1144 EEISERLEEAGGA-TSCQIEMNKKREAEFQKMRR----DLEEATLQHEATAAALRKKHAD 1198
Query: 514 ANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAETI-------KILRKKERQLKE 561
+ A +G +R+ KLE + +LELD+ + I K+ R E Q+ E
Sbjct: 1199 SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ EE Q++++ L K + RQL E+E + Q + ++LE
Sbjct: 1259 HRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE 1313
Score = 63.7 bits (148), Expect = 2e-09
Identities = 114/526 (21%), Positives = 225/526 (42%), Gaps = 44/526 (8%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
KKR E +K DL +E L E AA R K A ++A+ L E N+Q +
Sbjct: 1165 KKREAEFQKMRRDL--EEATLQHEAT--AAALRKKHADSVAE--LGEQIDNLQRVKQKLE 1218
Query: 202 DFQASRTLVNRDYT-NLSKNVLAKALMESKAMNSCDSRVTE---SITETVR-VRE-TSPT 255
++ L D T N+ + + AKA +E K + + ++ E ET R V + TS
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLE-KMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 256 TCVVRINTELPA-IDN--SYLNQLNELKET-VKQFDDLSVYILNDSSKQTSIEIEQLNAR 311
+ N EL +D + ++QL K T +Q +DL + + + ++ +AR
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 312 --------VVEAETKLKSEVTRIKKKLQIQITE--LELSLDVANKTNIDLQKTIKKQSLQ 361
E ET+ K+E+ R+ K ++ + + D +T +L++ KK + +
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE-ELEEAKKKLAQR 1396
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L E + + V + Q I+ L +VE + +R+ ++ E
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 422 QTRVNELTVINVNLSSSKAK-IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + E + + S +A+ + EL + Y+E + L + +Q E+ E
Sbjct: 1457 KQKYEE-SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1515
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN----------AIVGGKRIISKLEAR 530
L + I ++E V+K LE E + LEE EA+ A + +I +++E +
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ + + E+++ KR H ++++ + L E + ++ L + ++S
Sbjct: 1576 LAEKDEEMEQAKRNH---LRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
R AE + + + ++ Q +L+ A D + N++++ ++
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRN 1678
Score = 57.6 bits (133), Expect = 1e-07
Identities = 69/322 (21%), Positives = 150/322 (46%), Gaps = 35/322 (10%)
Query: 319 LKSEVTRIKKKLQ---IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE-VQR 374
+K E T +K+ L+ + ELE + + DLQ ++ + L + + D+ ++
Sbjct: 852 MKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
++Q+ + +++ + +E+ + KR+VE + E + +++L +
Sbjct: 912 KIQL--------EAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDIDDLEL---- 959
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK-------HTVEHLHEEQER 487
+ AK+E+E +T+E+ DE ++ E K ++ L E+++
Sbjct: 960 ---TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1016
Query: 488 IVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK---DMELELDEEKRR 544
+ + K LE +V ++ LE+ E + +R KLE +K + ++L+ +K++
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSLEQ-EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ 1075
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
E +K KK+ +L + + E++Q S LQ L++ ++ + +L E E ++
Sbjct: 1076 LDERLK---KKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL-EAERTARAK 1131
Query: 605 VTRVRR-FQRELEAAEDRADVA 625
V ++R RELE +R + A
Sbjct: 1132 VEKLRSDLSRELEEISERLEEA 1153
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/168 (21%), Positives = 79/168 (47%), Gaps = 5/168 (2%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E KE+ E + ++ L+ + E +E++V + K L+++V+ L + E
Sbjct: 844 EREKEMASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEE 903
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K I +LEA++K+M L++E+ +AE L K+R +++ + + D ++
Sbjct: 904 RCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAE----LTAKKRNVEDECSELKRDIDDLE 958
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L +EK + L E+ + + ++ + ++ L+ A +A
Sbjct: 959 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQA 1006
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 225 bits (550), Expect = 4e-58
Identities = 156/496 (31%), Positives = 261/496 (52%), Gaps = 28/496 (5%)
Query: 143 KKRMQEIEKELDLYEKEV-NLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
K+++ E + EL+ +KE +L +EL + Y + + Q LE RR +N +
Sbjct: 1461 KQKLDESQAELEAAQKESRSLSTELFKMRNAYE----EVVDQ--LETLRRENKNLQEEIS 1514
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
D + NL + K L+E + D +V E E S ++R+
Sbjct: 1515 DLTEQIAETGK---NLQEAEKTKKLVEQE---KSDLQVALEEVEGSLEHEESK---ILRV 1565
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS 321
EL + + ++ E E ++Q K+ S + V++AE + ++
Sbjct: 1566 QLELSQVKSELDRKVIEKDEEIEQL------------KRNSQRAAEALQSVLDAEIRSRN 1613
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
+ R+KKK++ + E+E+ L +N+ + Q+ ++ QL + Q H D+ R + +
Sbjct: 1614 DALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDLKE 1673
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
Q + +RR L E+EE++ EQ R +R EQ+ ++ RV L N +L ++K K
Sbjct: 1674 QLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKK 1733
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
+E ++A A+ + +E R A+E+ ++ T+ E L +EQ+ +E +KK+LE
Sbjct: 1734 LEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT 1793
Query: 502 VKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKE 561
VK++ RL+E E A+ GGK+ I KLE R++++E ELD E++R AE +K K ER++KE
Sbjct: 1794 VKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKE 1853
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
+ Q EED+KNI LQD ++K KV YKRQ E E + ++R RR Q ELE A +R
Sbjct: 1854 MTYQAEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAER 1913
Query: 622 ADVAESNLSLIRAKHR 637
AD+AES ++ +RAK R
Sbjct: 1914 ADIAESQVNKLRAKSR 1929
Score = 83.4 bits (197), Expect = 2e-15
Identities = 106/483 (21%), Positives = 206/483 (42%), Gaps = 37/483 (7%)
Query: 176 KSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSC 235
KS +A+ Q L EE +R ++ E K + A +R +L + + E +A
Sbjct: 1307 KSKQALTQQL-EELKRQMEEETKAK-NAMAHALQSSRHDCDLLREQYEE---EQEAKAEL 1361
Query: 236 DSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILN 295
++++ +E + + T + R EL +L E +E + + L
Sbjct: 1362 QRALSKANSEVAQWKTKYETDAIQRTE-ELEEAKKKLAQRLQEAEEKTETANSKCAS-LE 1419
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ ++ E+E L R +E + + + ++ + E + LD + QK
Sbjct: 1420 KTKQRLQGEVEDL-MRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKES 1478
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ S +L +++ Y+EV QL+ + Q I LT ++ E N ++A + K+ VE
Sbjct: 1479 RSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVE 1538
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ + Q + E + +L ++KI + V + ++ EL R E
Sbjct: 1539 QEKSDLQVALEE---VEGSLEHEESKILR----VQLELSQVKSEL-------DRKVIEKD 1584
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
+E L +R EA++ L+ E+++ + L R+ K+E + +ME
Sbjct: 1585 EEIEQLKRNSQRAA--EALQSVLDAEIRSRNDAL------------RLKKKMEGDLNEME 1630
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
++L R+ AET + LR + QLK+ + ++ ++ L++ L ++ + +L
Sbjct: 1631 IQLGHSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELE 1690
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAES-NLSLIRAKHRTFVTTSTVPGSQVYLVQ 654
E + +Q+ R ++EL A DR + S N SLI K + + +Q
Sbjct: 1691 EMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQ 1750
Query: 655 ESR 657
ESR
Sbjct: 1751 ESR 1753
Score = 77.8 bits (183), Expect = 1e-13
Identities = 87/384 (22%), Positives = 172/384 (44%), Gaps = 36/384 (9%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
E E++N+ +V + L+ + + +K+ I +LEL+L K + +K S ++T
Sbjct: 932 EEEEMNSELVAKKRNLEDKCSSLKR----DIDDLELTLTKVEKEKHATENKVKNLSEEMT 987
Query: 364 EIQTHYDEVQRQL-------QVTLDQYGVAQRRIQSLTG-------EVEEIRGNYEQALR 409
++ + ++ ++ Q TLD V + ++ L + +++ G+ EQ +
Sbjct: 988 ALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKK 1047
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADER--- 466
++ +E+ + + + ++L + K +IE++L + ++ + RI DE+
Sbjct: 1048 LRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQL--QARIDDEQVHS 1105
Query: 467 --YQRVQTELKHTVEHLHEEQERI----VKIEAVKKSLEIEVKNISVRLEEVEANAIVGG 520
+Q+ EL+ +E L EE E KIE + L E++ IS RLEE + A
Sbjct: 1106 LQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA-SGATSAQ 1164
Query: 521 KRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL 580
+ K EA + M +L+E +H T LRKK+ + + + E N+ ++ L
Sbjct: 1165 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ---ADSVAELGEQIDNLQRVKQKL 1221
Query: 581 EKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE--AAEDRADVAESNLSLIRAKHRT 638
EK ++ + +A +S + + R R +E +E +A E LI +
Sbjct: 1222 EKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAK-DEQQTQLIHDLNMQ 1280
Query: 639 FVTTSTVPGSQVYLVQESRALSSE 662
T G + V+E +L S+
Sbjct: 1281 KARLQTQNGELSHRVEEKESLISQ 1304
Score = 66.9 bits (156), Expect = 2e-10
Identities = 71/372 (19%), Positives = 158/372 (42%), Gaps = 11/372 (2%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ EL+E ++ L I S + E+E+++ R+ EA +++ + KK + +
Sbjct: 1118 RIEELEEEIEAEHTLRAKIEKQRS-DLARELEEISERLEEASGATSAQI-EMNKKREAEF 1175
Query: 335 TELELSLDVANKTNIDLQKTI-KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
++ L+ A + T+ KKQ+ + E+ D +QR Q + + I +
Sbjct: 1176 QKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDM 1235
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+E + + R R+VE Q+ E + + + T + +L+ KA+++ + ++
Sbjct: 1236 ASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRV 1295
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+E + + Q + +L+ + EE + + +S + + + EE E
Sbjct: 1296 EEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEE-E 1354
Query: 514 ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNI 573
A +R +SK + + + + + + + E ++ +KK L + + + EE +
Sbjct: 1355 QEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKK---LAQRLQEAEEKTETA 1411
Query: 574 SLLQDSLEKTSQK----VSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+ SLEKT Q+ V R L + R F + L + + D +++ L
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471
Query: 630 SLIRAKHRTFVT 641
+ + R+ T
Sbjct: 1472 EAAQKESRSLST 1483
Score = 64.5 bits (150), Expect = 1e-09
Identities = 91/486 (18%), Positives = 202/486 (41%), Gaps = 43/486 (8%)
Query: 148 EIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQ----NERMYKPDF 203
E EKE+ +++ E ++ R + + + L E++ +Q E + +
Sbjct: 848 EAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEE 907
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNS---CDSRVTESITETVRVRETSPTTCVVR 260
+ + ++ L + L E + MNS R E +++ + +
Sbjct: 908 RCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTK 967
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
+ E A +N N E+ + L+ K++ E Q ++ E
Sbjct: 968 VEKEKHATENKVKNLSEEMTALEENISKLT------KEKKSLQEAHQQTLDDLQVEEDKV 1021
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKT-------IKKQSLQLTEIQTHYDEVQ 373
+ + +I KL+ Q +LE SL+ K DL++ +K + +++ +++
Sbjct: 1022 NGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIE 1081
Query: 374 R----------QLQVTLDQYGV----AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE 419
QLQ +D V Q++I+ L +EE+ E ++ +E+Q
Sbjct: 1082 EKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRS 1141
Query: 420 ESQTRVNELTV-INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL-KHT 477
+ + E++ + ++ A+IE A++ ++ ++L A +++ L K
Sbjct: 1142 DLARELEEISERLEEASGATSAQIEMNKK-REAEFQKMRRDLEEATLQHEATAATLRKKQ 1200
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN--AIVGGKRIISKLEARIKDME 535
+ + E E+I ++ VK+ LE E + + ++++ +N A+ K I + ++D
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260
Query: 536 LELDEEKRRHAETIKILRKKERQLK----EVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E+ + + + I L ++ +L+ E+ + EE + IS L S + +Q++ K
Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320
Query: 592 RQLAEQ 597
RQ+ E+
Sbjct: 1321 RQMEEE 1326
Score = 62.9 bits (146), Expect = 3e-09
Identities = 89/504 (17%), Positives = 211/504 (41%), Gaps = 33/504 (6%)
Query: 142 QKKRMQEI--EKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
+K++++E +KE +L + + + E Q ++ K K + Q +EE ++ E
Sbjct: 1076 EKQQIEEKLKKKEFELSQLQARIDDE--QVHSLQFQKKIKEL-QARIEELEEEIEAEHTL 1132
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
+ + R+ + R+ +S+ L E+ S + + + +
Sbjct: 1133 RAKIEKQRSDLARELEEISER-----LEEASGATSAQIEMNKKREAEFQKMRRDLEEATL 1187
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
+ + + + EL E + + + + S + +EI+ + A +EA +K
Sbjct: 1188 QHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKS-ELKMEIDDM-ASNIEALSKS 1245
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
KS + R + ++ Q +E++ + + DL ++Q +QT E+ +++
Sbjct: 1246 KSNIERTCRTVEDQFSEIKAKDEQQTQLIHDL-------NMQKARLQTQNGELSHRVEEK 1298
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ Q+LT ++EE++ E+ + K ++ + S+ + L +K
Sbjct: 1299 ESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAK 1358
Query: 440 AKIEQELAIVAADYDEI-TKELRIADERYQRVQTELKHTVEHLHEEQERI-------VKI 491
A++++ L+ ++ + TK A +R + ++ K + L E +E+ +
Sbjct: 1359 AELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASL 1418
Query: 492 EAVKKSLEIEVKNISVRLEEVE-ANAIVGGK-----RIISKLEARIKDMELELDEEKRRH 545
E K+ L+ EV+++ LE A A + K +++++ + ++ + + EL+ ++
Sbjct: 1419 EKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKES 1478
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
L K +EV+ Q E ++ LQ+ + +++++ + L E E +
Sbjct: 1479 RSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVE 1538
Query: 606 TRVRRFQRELEAAEDRADVAESNL 629
Q LE E + ES +
Sbjct: 1539 QEKSDLQVALEEVEGSLEHEESKI 1562
Score = 54.0 bits (124), Expect = 2e-06
Identities = 35/169 (20%), Positives = 85/169 (50%), Gaps = 9/169 (5%)
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE- 513
E KE+ E ++R + EL + E +E++V + K L+++V++ + L + E
Sbjct: 848 EAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEE 907
Query: 514 -ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
++ K + LEA++K++ L+EE+ ++E + K+R L++ + D +
Sbjct: 908 RCEGLIKSKIL---LEAKVKELTERLEEEEEMNSELV----AKKRNLEDKCSSLKRDIDD 960
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
+ L +EK + L+E+ +++++++ + ++ L+ A +
Sbjct: 961 LELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQ 1009
Score = 46.4 bits (105), Expect = 3e-04
Identities = 54/214 (25%), Positives = 107/214 (50%), Gaps = 30/214 (14%)
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQR--------------VQTELKHTVEHLHEEQ 485
A+ E+E+A + D++ +EL ++ R + +Q +++ E+L + +
Sbjct: 847 AEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAE 906
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEA--NAIVGGKRII----SKLEARIKDMELELD 539
ER + K LE +VK ++ RLEE E + +V KR + S L+ I D+EL L
Sbjct: 907 ERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLT 966
Query: 540 E-EKRRHA--ETIKILRKKERQLKEVIIQCEEDQKNISLLQ----DSLEKTSQKVS-IYK 591
+ EK +HA +K L ++ L+E I + +++K++ D L+ KV+ + K
Sbjct: 967 KVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIK 1026
Query: 592 --RQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
+L +Q + S+ + ++ + +LE A+ + +
Sbjct: 1027 INAKLEQQTDDLEGSLEQEKKLRADLERAKRKLE 1060
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 210 bits (513), Expect = 1e-53
Identities = 142/498 (28%), Positives = 258/498 (51%), Gaps = 28/498 (5%)
Query: 143 KKRMQEIEKELDLYEKEVN-LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
K++ +E + LD +KEV L +EL + Y + Q L +N+Q E
Sbjct: 1479 KQKHEESQALLDASQKEVQALSTELLKLKNTYE---ESIVGQETLRRENKNLQEE----- 1530
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
V NL++ K L+E + + +VT TE R S ++
Sbjct: 1531 -ISNLTNQVREGTKNLTEMEKVKKLIEEE---KTEVQVTLEETEGALERNESK---ILHF 1583
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS 321
EL +L+E E ++ F ++ I+ L + + ++E K +
Sbjct: 1584 QLELLEAKAELERKLSEKDEEIENF-----------RRKQQCTIDSLQSSL-DSEAKSRI 1631
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
EVTR+KKK++ + E+EL L AN+ + K++ + +Q+ ++Q D+ + +
Sbjct: 1632 EVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKE 1691
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
Q VA+RR L E+E++R EQ R +R E++ E+ R+N N +L S K K
Sbjct: 1692 QVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKK 1751
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
+E ++A + + +E+ +E + A+E+ ++ E + E L ++Q+ I +E ++++E
Sbjct: 1752 LEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQT 1811
Query: 502 VKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKE 561
+ ++ RL E E A++G ++ I KLE+R++++E EL+ E RR AE + R+ ER +KE
Sbjct: 1812 ITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKE 1871
Query: 562 VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
+ Q EED+KN+S +Q ++K KV YK+Q+ E + Q +++ ++ Q EL ++R
Sbjct: 1872 LTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKER 1931
Query: 622 ADVAESNLSLIRAKHRTF 639
A+VAES ++ ++ K R F
Sbjct: 1932 AEVAESQVNKLKIKAREF 1949
Score = 73.7 bits (173), Expect = 2e-12
Identities = 81/388 (20%), Positives = 176/388 (45%), Gaps = 38/388 (9%)
Query: 305 IEQLNARVVEAETKLKSEVTR-------IKKKLQIQITELELSLDVANKTNIDLQKTIKK 357
+ ++NA +V+ K ++ V + KK+L I++ E ++ VAN N L++ +
Sbjct: 1383 LSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQ 1442
Query: 358 QSLQLTEIQTHYDEV--------QRQLQ--VTLDQY-----------GVAQRRIQSLTGE 396
L+L + + +V Q+QLQ L + +Q+ +Q+L+ E
Sbjct: 1443 LQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTE 1502
Query: 397 VEEIRGNYEQAL-------RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIV 449
+ +++ YE+++ R ++++++ +V E T + K IE+E V
Sbjct: 1503 LLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEV 1562
Query: 450 AADYDEITKELRIADERYQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVR 508
+E L + + Q EL L + E+ +IE ++ + + ++
Sbjct: 1563 QVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSS 1622
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
L+ EA + + R+ K+E + +MEL+L R+ +E K L + + Q+K++ +Q ++
Sbjct: 1623 LDS-EAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDD 1681
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADV-AES 627
+ S L++ + ++ S+ + +L + + +Q+ R + EL A +R ++
Sbjct: 1682 STQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQ 1741
Query: 628 NLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
N SL+ K + + + +VQE
Sbjct: 1742 NTSLLSQKKKLEADVARMQKEAEEVVQE 1769
Score = 71.7 bits (168), Expect = 8e-12
Identities = 63/318 (19%), Positives = 138/318 (43%), Gaps = 11/318 (3%)
Query: 309 NARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
++ V E LK E +++K L+ + E + + L + LQL Q
Sbjct: 864 SSEVGEEVAGLKEECAQLQKALE----KSEFQREELKAKQVSLTQEKNDLILQLQAEQET 919
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
V+ Q + + + R++ L+ VEE + R +E + E + +++L
Sbjct: 920 LANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDL 979
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+ V K E ++ + + + + +++ + + VQ + T++ LH E+E++
Sbjct: 980 ETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKL 1039
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
+ LE +V + LE+ E A + +R + KLE +K ++ +
Sbjct: 1040 SSLSKANLKLEQQVDELEGALEQ-ERKARMNCERELHKLEGNLKLNRESMENLESSQRHL 1098
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
+ LRKKE +L ++ + E ++ ++ LQ ++++ ++ K E + + TR
Sbjct: 1099 AEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLK------EKLEAERTTRA 1152
Query: 609 RRFQRELEAAEDRADVAE 626
+ + + +D AD+ E
Sbjct: 1153 KMERERADLTQDLADLNE 1170
Score = 62.5 bits (145), Expect = 5e-09
Identities = 62/345 (17%), Positives = 154/345 (44%), Gaps = 11/345 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
+L+++ V+ L V L + K+ +I+ L ++ EAE ++++ R + L +
Sbjct: 1108 ELSQMNSKVENEKGL-VAQLQKTVKELQTQIKDLKEKL-EAERTTRAKMERERADLTQDL 1165
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
+L L+ +++ + KKQ ++ ++ +E + T + +R SL
Sbjct: 1166 ADLNERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETT--SASLKKRHADSLA 1223
Query: 395 ---GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
G+VE ++ ++ + K ++ + ++ TRV ++T N E+ L A
Sbjct: 1224 ELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATA 1283
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
D++T+ + ++ +E + L E++ I ++ K + +++++ +LE+
Sbjct: 1284 KLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEK 1343
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
E + + K + + + +EE+ AE + L K ++ + ++ E
Sbjct: 1344 -ETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYE---N 1399
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
N+ + LE ++++I ++ AE G++ + R + +L+
Sbjct: 1400 NVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQ 1444
Score = 56.8 bits (131), Expect = 2e-07
Identities = 66/351 (18%), Positives = 150/351 (42%), Gaps = 18/351 (5%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
+++ L E V +F + + LN ++K E Q + E + S +++ KL+ Q
Sbjct: 995 HKVKNLTEEV-EFLNEDISKLNRAAKVVQ-EAHQQTLDDLHMEEEKLSSLSKANLKLEQQ 1052
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ ELE +L+ K ++ ++ + K L + + ++ + ++ + + +
Sbjct: 1053 VDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQM 1112
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+VE +G Q + + ++ Q ++ + ++ + +A + Q+L AD
Sbjct: 1113 NSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDL----ADL 1168
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEV 512
+E +E+ + + + + ++ LH + +E + E SL+ K + L E+
Sbjct: 1169 NERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETTSASLK---KRHADSLAEL 1225
Query: 513 EANAIVGGKRIISKLEARIKDMELELD-------EEKRRHAETIKILRKKERQLKEVIIQ 565
E + +++ KLE D++LE+D + R A K+ E +L E +
Sbjct: 1226 EGQ-VENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAK 1284
Query: 566 CEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
++ + + L K + + R+L E+E + Q F R++E
Sbjct: 1285 LDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIE 1335
>S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy chain
protein.
Length = 231
Score = 177 bits (431), Expect = 1e-43
Identities = 88/218 (40%), Positives = 144/218 (66%)
Query: 420 ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVE 479
++ RV L N +L ++K K+E +++ + + ++I +E R A+E+ ++ T+ E
Sbjct: 4 DASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAE 63
Query: 480 HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELD 539
L +EQ+ +E +KK++E VK++ +RL+E E A+ GGK+ I KLEAR++++E E++
Sbjct: 64 ELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 123
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
E++R+AE +K LRK ER++KE+ Q EED+KNI LQD ++K KV YKRQ E E
Sbjct: 124 SEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEE 183
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
S ++ + R+ Q ELE AE+RAD+AES ++ +R K R
Sbjct: 184 QSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 221
Score = 45.6 bits (103), Expect = 6e-04
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 3/149 (2%)
Query: 279 LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET-KLKSEVTRIKKKLQIQITEL 337
+ E +K+ D S + L K ++ L R+ EAE LK +I+K L+ ++ EL
Sbjct: 61 MAEELKKEQDTSAH-LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK-LEARVREL 118
Query: 338 ELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEV 397
E ++ K N + K ++K ++ E+ +E ++ + D Q +++S +
Sbjct: 119 EGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQA 178
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVN 426
EE L R ++ + EE++ R +
Sbjct: 179 EEAEEQSNTNLAKFRKLQHELEEAEERAD 207
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 151 bits (365), Expect = 1e-35
Identities = 115/480 (23%), Positives = 227/480 (47%), Gaps = 24/480 (5%)
Query: 164 SELRQKA-AMYRGKSAKAI--AQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKN 220
+E R +A A R K KA+ A+ L E + + ER+ K L++ SK+
Sbjct: 1461 AEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS------SKD 1514
Query: 221 VLAKALME-SKAMNSCDSRVTESITETVRVRETSPTT--CVVRINTELPAIDNSYLNQLN 277
+ K++ E K+ + + +V E T+ + + T +R+ L A+ + L
Sbjct: 1515 DVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQ 1574
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
E ++ KQ ++ ++ A + E E K +S +KKL++ + +L
Sbjct: 1575 GRDEQSEE-----------KKKQLVRQVREMEAEL-EDERKQRSMAVAARKKLEMDLKDL 1622
Query: 338 ELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEV 397
E +D ANK + K ++K Q+ + D+ + + L Q +++++S+ E+
Sbjct: 1623 EAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 1682
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
+++ A R KR +Q+ +E + + K ++E +A + + +E
Sbjct: 1683 IQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQ 1742
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
+ ++R ++ ++ L+ E+ K E ++ LE + K + V+L+E+E
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K I+ LEA+I +E +LD E + K +R+ E++LK+V++Q +++++N +
Sbjct: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
D +K S ++ KRQL E E +Q++ R+ QRELE A + AD +S ++ K R
Sbjct: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 72.5 bits (170), Expect = 4e-12
Identities = 83/384 (21%), Positives = 166/384 (43%), Gaps = 40/384 (10%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
+L +L+E +D + + + K I + + E E K KS + ++K K + I
Sbjct: 972 KLKKLEEEQIILEDQNCKLAKEK-KLLEDRIAEFTTNLTEEEEKSKS-LAKLKNKHEAMI 1029
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
T+LE L K +L+KT +K T++ E+Q Q+ Q + +Q+
Sbjct: 1030 TDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAAL 1089
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
VEE AL+ R +E Q E ++++L A +
Sbjct: 1090 ARVEEEAAQKNMALKKIRELESQISE---------------------LQEDLESERASRN 1128
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRLE 510
+ K+ R E + ++TEL+ T++ +QE R ++ +KK+LE E K +++
Sbjct: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 511 EVEANAIVGGKRIISKLE------ARIKDMELELDEEKRRHAETIKILRK----KERQLK 560
E+ + + +LE A ++ + L+ E+ A +K+L + E + K
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK 1248
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
+V Q +E Q + + + + KV+ + +L G+ QS ++ + ++ A E
Sbjct: 1249 KVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES 1308
Query: 621 RADVAESNLSLIRAKHRTFVTTST 644
+ + L++ ++R ++ ST
Sbjct: 1309 Q---LQDTQELLQEENRQKLSLST 1329
Score = 70.5 bits (165), Expect = 2e-11
Identities = 75/366 (20%), Positives = 178/366 (48%), Gaps = 11/366 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++N LK+T+++ + + ++ S +E+L A +E ++K+ + + K+ L+ +
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEEL-AEQLEQTKRVKANLEKAKQTLENER 1226
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
EL + V + D + KK QL E+Q ++E +R D+ Q + ++T
Sbjct: 1227 GELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVT 1286
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
G + + + + ++E Q +++Q + E ++LS+ ++E E +
Sbjct: 1287 GLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE 1346
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E + +++ + ++ + + + + E VK+ L+ +++ +S R EE A
Sbjct: 1347 EEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA 1406
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL--KEVIIQCEEDQKN 572
A ++ ++L+ + D+ ++LD + R+ A ++ +KK QL +E I + ++
Sbjct: 1407 -AYDKLEKTKTRLQQELDDLLVDLDHQ-RQSACNLEKKQKKFDQLLAEEKTISAKYAEER 1464
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS-VTRV-RRFQRELE-AAEDRADVAESNL 629
++ EK ++ +S+ + A +E M Q++ + R+ ++F+ E+E + DV +S
Sbjct: 1465 DRAEAEAREKETKALSLAR---ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 630 SLIRAK 635
L ++K
Sbjct: 1522 ELEKSK 1527
Score = 67.3 bits (157), Expect = 2e-10
Identities = 66/324 (20%), Positives = 148/324 (45%), Gaps = 7/324 (2%)
Query: 306 EQLNARV---VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
EQL A EAE +L++ +T K++L+ +LE ++ + LQ KK +
Sbjct: 887 EQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNI 945
Query: 363 TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
E++ +E + Q + + +++ L E + + + K+ +E + E
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
T + E + +L+ K K E + + K+ + ++ ++++ + + +
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E Q +I +++ E E++ R+EE A + K+ I +LE++I +++ +L+ E+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK-IRELESQISELQEDLESER 1124
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ K R +L+ + + E+ + + Q+ K Q+V+I K+ L E+ +
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+ +R Q+ +A E+ A+ E
Sbjct: 1185 AQIQEMR--QKHSQAVEELAEQLE 1206
Score = 62.5 bits (145), Expect = 5e-09
Identities = 89/510 (17%), Positives = 214/510 (41%), Gaps = 30/510 (5%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ--TLLEESRRNVQNERMYKPD 202
++ E++ +L E+E+ ++ A + + K I + + + E + ++++ER +
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNK 1129
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
+ + + + L K L L + A S+ + + + E T +I
Sbjct: 1130 AEKQKRDLGEELEAL-KTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+ + + EL E ++Q + + + +KQT A V+ + K +
Sbjct: 1189 E----MRQKHSQAVEELAEQLEQTKRVKANL--EKAKQTLENERGELANEVKVLLQGKGD 1242
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+KK++ Q+ EL++ + + +L + K ++L + + +
Sbjct: 1243 SEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKD 1302
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAK 441
+ + ++Q T E+ + + +L K + VE + + ++ E NL A
Sbjct: 1303 FSALESQLQD-TQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIAT 1361
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
+ ++A + ++ L A+E +++Q +L+ + E+ K+E K L+ E
Sbjct: 1362 LHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQE 1421
Query: 502 VKNISVRLEEVEANA------------IVGGKRIISKLEARIKDM-ELELDEEKRRHAET 548
+ ++ V L+ +A ++ ++ IS A +D E E E++ +
Sbjct: 1422 LDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSL 1481
Query: 549 IKILRK---KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
+ L + ++ +L+ + Q + +++ +D + K+ ++ KR L +Q ++
Sbjct: 1482 ARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQV---EEMK 1538
Query: 606 TRVRRFQRELEAAEDRADVAESNLSLIRAK 635
T++ + EL+A ED E NL ++A+
Sbjct: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQ 1568
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 151 bits (365), Expect = 1e-35
Identities = 115/480 (23%), Positives = 227/480 (47%), Gaps = 24/480 (5%)
Query: 164 SELRQKA-AMYRGKSAKAI--AQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKN 220
+E R +A A R K KA+ A+ L E + + ER+ K L++ SK+
Sbjct: 1461 AEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS------SKD 1514
Query: 221 VLAKALME-SKAMNSCDSRVTESITETVRVRETSPTT--CVVRINTELPAIDNSYLNQLN 277
+ K++ E K+ + + +V E T+ + + T +R+ L A+ + L
Sbjct: 1515 DVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQ 1574
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
E ++ KQ ++ ++ A + E E K +S +KKL++ + +L
Sbjct: 1575 GRDEQSEE-----------KKKQLVRQVREMEAEL-EDERKQRSMAVAARKKLEMDLKDL 1622
Query: 338 ELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEV 397
E +D ANK + K ++K Q+ + D+ + + L Q +++++S+ E+
Sbjct: 1623 EAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 1682
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
+++ A R KR +Q+ +E + + K ++E +A + + +E
Sbjct: 1683 IQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQ 1742
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
+ ++R ++ ++ L+ E+ K E ++ LE + K + V+L+E+E
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K I+ LEA+I +E +LD E + K +R+ E++LK+V++Q +++++N +
Sbjct: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
D +K S ++ KRQL E E +Q++ R+ QRELE A + AD +S ++ K R
Sbjct: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 72.5 bits (170), Expect = 4e-12
Identities = 83/384 (21%), Positives = 166/384 (43%), Gaps = 40/384 (10%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
+L +L+E +D + + + K I + + E E K KS + ++K K + I
Sbjct: 972 KLKKLEEEQIILEDQNCKLAKEK-KLLEDRIAEFTTNLTEEEEKSKS-LAKLKNKHEAMI 1029
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
T+LE L K +L+KT +K T++ E+Q Q+ Q + +Q+
Sbjct: 1030 TDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAAL 1089
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
VEE AL+ R +E Q E ++++L A +
Sbjct: 1090 ARVEEEAAQKNMALKKIRELESQISE---------------------LQEDLESERASRN 1128
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRLE 510
+ K+ R E + ++TEL+ T++ +QE R ++ +KK+LE E K +++
Sbjct: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 511 EVEANAIVGGKRIISKLE------ARIKDMELELDEEKRRHAETIKILRK----KERQLK 560
E+ + + +LE A ++ + L+ E+ A +K+L + E + K
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK 1248
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
+V Q +E Q + + + + KV+ + +L G+ QS ++ + ++ A E
Sbjct: 1249 KVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES 1308
Query: 621 RADVAESNLSLIRAKHRTFVTTST 644
+ + L++ ++R ++ ST
Sbjct: 1309 Q---LQDTQELLQEENRQKLSLST 1329
Score = 70.5 bits (165), Expect = 2e-11
Identities = 75/366 (20%), Positives = 178/366 (48%), Gaps = 11/366 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++N LK+T+++ + + ++ S +E+L A +E ++K+ + + K+ L+ +
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEEL-AEQLEQTKRVKANLEKAKQTLENER 1226
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
EL + V + D + KK QL E+Q ++E +R D+ Q + ++T
Sbjct: 1227 GELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVT 1286
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
G + + + + ++E Q +++Q + E ++LS+ ++E E +
Sbjct: 1287 GLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE 1346
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E + +++ + ++ + + + + E VK+ L+ +++ +S R EE A
Sbjct: 1347 EEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA 1406
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL--KEVIIQCEEDQKN 572
A ++ ++L+ + D+ ++LD + R+ A ++ +KK QL +E I + ++
Sbjct: 1407 -AYDKLEKTKTRLQQELDDLLVDLDHQ-RQSACNLEKKQKKFDQLLAEEKTISAKYAEER 1464
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS-VTRV-RRFQRELE-AAEDRADVAESNL 629
++ EK ++ +S+ + A +E M Q++ + R+ ++F+ E+E + DV +S
Sbjct: 1465 DRAEAEAREKETKALSLAR---ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 630 SLIRAK 635
L ++K
Sbjct: 1522 ELEKSK 1527
Score = 67.3 bits (157), Expect = 2e-10
Identities = 66/324 (20%), Positives = 148/324 (45%), Gaps = 7/324 (2%)
Query: 306 EQLNARV---VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
EQL A EAE +L++ +T K++L+ +LE ++ + LQ KK +
Sbjct: 887 EQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNI 945
Query: 363 TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
E++ +E + Q + + +++ L E + + + K+ +E + E
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
T + E + +L+ K K E + + K+ + ++ ++++ + + +
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E Q +I +++ E E++ R+EE A + K+ I +LE++I +++ +L+ E+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK-IRELESQISELQEDLESER 1124
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ K R +L+ + + E+ + + Q+ K Q+V+I K+ L E+ +
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+ +R Q+ +A E+ A+ E
Sbjct: 1185 AQIQEMR--QKHSQAVEELAEQLE 1206
Score = 62.5 bits (145), Expect = 5e-09
Identities = 89/510 (17%), Positives = 214/510 (41%), Gaps = 30/510 (5%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ--TLLEESRRNVQNERMYKPD 202
++ E++ +L E+E+ ++ A + + K I + + + E + ++++ER +
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNK 1129
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
+ + + + L K L L + A S+ + + + E T +I
Sbjct: 1130 AEKQKRDLGEELEAL-KTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+ + + EL E ++Q + + + +KQT A V+ + K +
Sbjct: 1189 E----MRQKHSQAVEELAEQLEQTKRVKANL--EKAKQTLENERGELANEVKVLLQGKGD 1242
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+KK++ Q+ EL++ + + +L + K ++L + + +
Sbjct: 1243 SEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKD 1302
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAK 441
+ + ++Q T E+ + + +L K + VE + + ++ E NL A
Sbjct: 1303 FSALESQLQD-TQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIAT 1361
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
+ ++A + ++ L A+E +++Q +L+ + E+ K+E K L+ E
Sbjct: 1362 LHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQE 1421
Query: 502 VKNISVRLEEVEANA------------IVGGKRIISKLEARIKDM-ELELDEEKRRHAET 548
+ ++ V L+ +A ++ ++ IS A +D E E E++ +
Sbjct: 1422 LDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSL 1481
Query: 549 IKILRK---KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
+ L + ++ +L+ + Q + +++ +D + K+ ++ KR L +Q ++
Sbjct: 1482 ARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQV---EEMK 1538
Query: 606 TRVRRFQRELEAAEDRADVAESNLSLIRAK 635
T++ + EL+A ED E NL ++A+
Sbjct: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQ 1568
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 151 bits (365), Expect = 1e-35
Identities = 115/480 (23%), Positives = 227/480 (47%), Gaps = 24/480 (5%)
Query: 164 SELRQKA-AMYRGKSAKAI--AQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKN 220
+E R +A A R K KA+ A+ L E + + ER+ K L++ SK+
Sbjct: 1461 AEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS------SKD 1514
Query: 221 VLAKALME-SKAMNSCDSRVTESITETVRVRETSPTT--CVVRINTELPAIDNSYLNQLN 277
+ K++ E K+ + + +V E T+ + + T +R+ L A+ + L
Sbjct: 1515 DVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQ 1574
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
E ++ KQ ++ ++ A + E E K +S +KKL++ + +L
Sbjct: 1575 GRDEQSEE-----------KKKQLVRQVREMEAEL-EDERKQRSMAVAARKKLEMDLKDL 1622
Query: 338 ELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEV 397
E +D ANK + K ++K Q+ + D+ + + L Q +++++S+ E+
Sbjct: 1623 EAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 1682
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
+++ A R KR +Q+ +E + + K ++E +A + + +E
Sbjct: 1683 IQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQ 1742
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
+ ++R ++ ++ L+ E+ K E ++ LE + K + V+L+E+E
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K I+ LEA+I +E +LD E + K +R+ E++LK+V++Q +++++N +
Sbjct: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
D +K S ++ KRQL E E +Q++ R+ QRELE A + AD +S ++ K R
Sbjct: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 72.5 bits (170), Expect = 4e-12
Identities = 83/384 (21%), Positives = 166/384 (43%), Gaps = 40/384 (10%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
+L +L+E +D + + + K I + + E E K KS + ++K K + I
Sbjct: 972 KLKKLEEEQIILEDQNCKLAKEK-KLLEDRIAEFTTNLTEEEEKSKS-LAKLKNKHEAMI 1029
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
T+LE L K +L+KT +K T++ E+Q Q+ Q + +Q+
Sbjct: 1030 TDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAAL 1089
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
VEE AL+ R +E Q E ++++L A +
Sbjct: 1090 ARVEEEAAQKNMALKKIRELESQISE---------------------LQEDLESERASRN 1128
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRLE 510
+ K+ R E + ++TEL+ T++ +QE R ++ +KK+LE E K +++
Sbjct: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 511 EVEANAIVGGKRIISKLE------ARIKDMELELDEEKRRHAETIKILRK----KERQLK 560
E+ + + +LE A ++ + L+ E+ A +K+L + E + K
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK 1248
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
+V Q +E Q + + + + KV+ + +L G+ QS ++ + ++ A E
Sbjct: 1249 KVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES 1308
Query: 621 RADVAESNLSLIRAKHRTFVTTST 644
+ + L++ ++R ++ ST
Sbjct: 1309 Q---LQDTQELLQEENRQKLSLST 1329
Score = 70.5 bits (165), Expect = 2e-11
Identities = 75/366 (20%), Positives = 178/366 (48%), Gaps = 11/366 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++N LK+T+++ + + ++ S +E+L A +E ++K+ + + K+ L+ +
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEEL-AEQLEQTKRVKANLEKAKQTLENER 1226
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
EL + V + D + KK QL E+Q ++E +R D+ Q + ++T
Sbjct: 1227 GELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVT 1286
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
G + + + + ++E Q +++Q + E ++LS+ ++E E +
Sbjct: 1287 GLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE 1346
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E + +++ + ++ + + + + E VK+ L+ +++ +S R EE A
Sbjct: 1347 EEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA 1406
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL--KEVIIQCEEDQKN 572
A ++ ++L+ + D+ ++LD + R+ A ++ +KK QL +E I + ++
Sbjct: 1407 -AYDKLEKTKTRLQQELDDLLVDLDHQ-RQSACNLEKKQKKFDQLLAEEKTISAKYAEER 1464
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS-VTRV-RRFQRELE-AAEDRADVAESNL 629
++ EK ++ +S+ + A +E M Q++ + R+ ++F+ E+E + DV +S
Sbjct: 1465 DRAEAEAREKETKALSLAR---ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 630 SLIRAK 635
L ++K
Sbjct: 1522 ELEKSK 1527
Score = 67.3 bits (157), Expect = 2e-10
Identities = 66/324 (20%), Positives = 148/324 (45%), Gaps = 7/324 (2%)
Query: 306 EQLNARV---VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
EQL A EAE +L++ +T K++L+ +LE ++ + LQ KK +
Sbjct: 887 EQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNI 945
Query: 363 TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
E++ +E + Q + + +++ L E + + + K+ +E + E
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
T + E + +L+ K K E + + K+ + ++ ++++ + + +
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E Q +I +++ E E++ R+EE A + K+ I +LE++I +++ +L+ E+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK-IRELESQISELQEDLESER 1124
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ K R +L+ + + E+ + + Q+ K Q+V+I K+ L E+ +
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+ +R Q+ +A E+ A+ E
Sbjct: 1185 AQIQEMR--QKHSQAVEELAEQLE 1206
Score = 62.5 bits (145), Expect = 5e-09
Identities = 89/510 (17%), Positives = 214/510 (41%), Gaps = 30/510 (5%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ--TLLEESRRNVQNERMYKPD 202
++ E++ +L E+E+ ++ A + + K I + + + E + ++++ER +
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNK 1129
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
+ + + + L K L L + A S+ + + + E T +I
Sbjct: 1130 AEKQKRDLGEELEAL-KTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+ + + EL E ++Q + + + +KQT A V+ + K +
Sbjct: 1189 E----MRQKHSQAVEELAEQLEQTKRVKANL--EKAKQTLENERGELANEVKVLLQGKGD 1242
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+KK++ Q+ EL++ + + +L + K ++L + + +
Sbjct: 1243 SEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKD 1302
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAK 441
+ + ++Q T E+ + + +L K + VE + + ++ E NL A
Sbjct: 1303 FSALESQLQD-TQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIAT 1361
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
+ ++A + ++ L A+E +++Q +L+ + E+ K+E K L+ E
Sbjct: 1362 LHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQE 1421
Query: 502 VKNISVRLEEVEANA------------IVGGKRIISKLEARIKDM-ELELDEEKRRHAET 548
+ ++ V L+ +A ++ ++ IS A +D E E E++ +
Sbjct: 1422 LDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSL 1481
Query: 549 IKILRK---KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
+ L + ++ +L+ + Q + +++ +D + K+ ++ KR L +Q ++
Sbjct: 1482 ARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQV---EEMK 1538
Query: 606 TRVRRFQRELEAAEDRADVAESNLSLIRAK 635
T++ + EL+A ED E NL ++A+
Sbjct: 1539 TQLEELEDELQATEDAKLRLEVNLQAMKAQ 1568
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 150 bits (363), Expect = 2e-35
Identities = 115/480 (23%), Positives = 227/480 (47%), Gaps = 24/480 (5%)
Query: 164 SELRQKA-AMYRGKSAKAI--AQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKN 220
+E R +A A R K KA+ A+ L E + + ER+ K L++ SK+
Sbjct: 748 AEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS------SKD 801
Query: 221 VLAKALME-SKAMNSCDSRVTESITETVRVRETSPTT--CVVRINTELPAIDNSYLNQLN 277
+ K++ E K+ + + +V E T+ + + T +R+ L A+ + L
Sbjct: 802 DVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQ 861
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
E ++ KQ ++ ++ A + E E K +S +KKL++ + +L
Sbjct: 862 GRDEQSEE-----------KKKQLVRQVREMEAEL-EDERKQRSMAVAARKKLEMDLKDL 909
Query: 338 ELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEV 397
E +D ANK + K ++K Q+ + D+ + + L Q +++++S+ E+
Sbjct: 910 EAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEM 969
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
+++ A R KR +Q+ +E + + K ++E +A + + +E
Sbjct: 970 IQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQ 1029
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
+ ++R ++ ++ L+ E+ K E ++ LE + K + V+L+E+E
Sbjct: 1030 GNTELINDRLKKANLQIDQINADLNLERGHAQKNENARQQLERQNKELKVKLQEMEGTVK 1089
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K I+ LEA+I +E +LD E + K +R+ E++LK+V++Q +++++N +
Sbjct: 1090 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1149
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
D +K S ++ KRQL E E +Q++ R+ QRELE A + AD +S ++ K R
Sbjct: 1150 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1209
Score = 77.4 bits (182), Expect = 2e-13
Identities = 99/464 (21%), Positives = 201/464 (43%), Gaps = 22/464 (4%)
Query: 157 EKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTN 216
E NL E + ++ + K+ T LEE R + +R + + +R + D T+
Sbjct: 289 EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ---ELEKTRRKLEGDSTD 345
Query: 217 LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQL 276
LS + ++ + E RV E + + N L I +Q+
Sbjct: 346 LSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA-----AQKNMALKKI-RELESQI 399
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTR--IKKKLQIQI 334
+EL+E ++ + S N + KQ E+L A E E L S + ++ K + ++
Sbjct: 400 SELQEDLES-ERAS---RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEV 455
Query: 335 TELELSLDVANKTN-IDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG-VAQRRIQS 392
L+ +L+ KT+ +Q+ +K S + E+ ++ +R ++ L++ +
Sbjct: 456 NILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR-VKANLEKAKQTLENERGE 514
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
L EV+ + + ++ VE Q +E Q + NE + L+ K++ EL V
Sbjct: 515 LANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGL 574
Query: 453 YDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
+ + + + ++++L+ T E L EE + + + K +E E + +LEE
Sbjct: 575 LSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEE 634
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
E A ++ I+ L A++ DM+ ++ E+ ET + +++K ++ E + Q E++
Sbjct: 635 EEEAKHNLEKQIATLHAQVADMKKKM-EDSVGCLETAEEVKRKLQKDLEGLSQRHEEK-- 691
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
D LEKT ++ L +QS + + Q++ +
Sbjct: 692 -VAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFD 734
Score = 67.7 bits (158), Expect = 1e-10
Identities = 66/324 (20%), Positives = 148/324 (45%), Gaps = 7/324 (2%)
Query: 306 EQLNARV---VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
EQL A EAE +L++ +T K++L+ +LE ++ + LQ KK +
Sbjct: 173 EQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNI 231
Query: 363 TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
E++ +E + Q + + +++ L E + + + K+ +E + E
Sbjct: 232 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 291
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
T + E + +L+ K K E + + K+ + ++ ++++ + + +
Sbjct: 292 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 351
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E Q +I +++ E E++ R+EE A + K+ I +LE++I +++ +L+ E+
Sbjct: 352 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK-IRELESQISELQEDLESER 410
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ K R +L+ + + E+ + + Q+ K Q+V+I K+ L E+ +
Sbjct: 411 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 470
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+ +R Q+ +A E+ A+ E
Sbjct: 471 AQIQEMR--QKHSQAVEELAEQLE 492
Score = 61.7 bits (143), Expect = 8e-09
Identities = 55/264 (20%), Positives = 118/264 (44%), Gaps = 17/264 (6%)
Query: 385 VAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV-----INVNLSSSK 439
V+++ + + E E ++ +Q R +E + +SQ +L + L +
Sbjct: 126 VSRQEEEMMAKEEELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQAETELCAEA 185
Query: 440 AKIEQELAIVAADYDEITKELRIA----DERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
++ L + +EI +L +ERYQ +Q E K +++ E +E++ + E+ +
Sbjct: 186 EELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESAR 245
Query: 496 KSLEIEVKNISVRLEEVEANAIV----GGKRIISK--LEARIKDMELELDEEKRRHAETI 549
+ L++E +L+++E I+ K K LE RI + L EE+ +
Sbjct: 246 QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 305
Query: 550 KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
K+ K E + ++ + ++K L+ + K + Q+AE + + ++
Sbjct: 306 KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLA 365
Query: 610 RFQRELEAAEDRA--DVAESNLSL 631
+ + EL+AA R + A+ N++L
Sbjct: 366 KKEEELQAALARVEEEAAQKNMAL 389
Score = 56.8 bits (131), Expect = 2e-07
Identities = 99/508 (19%), Positives = 220/508 (43%), Gaps = 58/508 (11%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
K+++E+E ++ E + +L SE +A+ + + K LE + +++
Sbjct: 390 KKIRELESQIS--ELQEDLESE---RASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQ 444
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
Q R+ ++ L K + +A + + ++++ E E + R+
Sbjct: 445 QELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK-----RVKA 499
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
L + N+ EL VK +L + + + +++ A++ E + K +E
Sbjct: 500 NLEKAKQTLENERGELANEVK--------VLLQGGRDSEHKRKKVEAQLQELQVKF-NEG 550
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
R++ +L ++T+L++ LD N T + Q K S +LT+ + ++ QLQ T +
Sbjct: 551 ERVRTELADKVTKLQVELD--NVTGLLSQSDSK--SSKLTK---DFSALESQLQDTQELL 603
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
R+ SL+ +++++ K S +Q EE + NL A +
Sbjct: 604 QEENRQKLSLSTKLKQVEDE-------KNSFREQLEEEEEEAKH------NLEKQIATLH 650
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
++A + ++ L A+E +++Q +L+ + E+ K+E K L+ E+
Sbjct: 651 AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELD 710
Query: 504 NISVRLEEVEANA------------IVGGKRIISKLEARIKDM-ELELDEEKRRHAETIK 550
++ V L+ +A ++ ++ IS A +D E E E++ + +
Sbjct: 711 DLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLAR 770
Query: 551 ILRK---KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
L + ++ +L+ + Q + +++ +D + K+ ++ KR L +Q ++ T+
Sbjct: 771 ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQV---EEMKTQ 827
Query: 608 VRRFQRELEAAEDRADVAESNLSLIRAK 635
+ + EL+A ED E NL ++A+
Sbjct: 828 LEELEDELQATEDAKLRLEVNLQAMKAQ 855
>AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein.
Length = 563
Score = 149 bits (362), Expect = 2e-35
Identities = 86/342 (25%), Positives = 173/342 (50%), Gaps = 1/342 (0%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ KQ ++ ++ A + E E K +S +KKL++ + +LE +D ANK + K +
Sbjct: 185 EKKKQLVRQVREMEAEL-EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQL 243
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+K Q+ + D+ + + L Q +++++S+ E+ +++ A R KR +
Sbjct: 244 RKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQ 303
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ +E + + K ++E +A + + +E + ++R ++ ++
Sbjct: 304 QERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 363
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
L+ E+ K E ++ LE + K + V+L+E+E K I+ LEA+I +E
Sbjct: 364 QINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLE 423
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
+LD E + K +R+ E++LK+V++Q +++++N +D +K S ++ KRQL
Sbjct: 424 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 483
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E E +Q++ R+ QRELE A + AD +S ++ K R
Sbjct: 484 EAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 525
Score = 87.4 bits (207), Expect = 1e-16
Identities = 61/330 (18%), Positives = 162/330 (49%), Gaps = 5/330 (1%)
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
+E + K+E+ R+ K+ + ++ +L S D K+ +L+K+ + Q+ E++T +E+
Sbjct: 88 LEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 147
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+ +LQ T D + +Q++ + E +++G EQ+ K+ + +Q E + + +
Sbjct: 148 EDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQ 207
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI 491
+++ K+E +L + A D K A ++ +++Q ++K + L + + +I
Sbjct: 208 RSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEI 267
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
A K E ++K++ + +++ + +R + + ++ E+ + A ++
Sbjct: 268 LAQAKENEKKLKSMEAEMIQLQ-EELAAAERAKRQAQQERDELADEIANSSGKGALALEE 326
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
R+ E ++ ++ + EE+Q N L+ D L+K + ++ L + +Q++ ++
Sbjct: 327 KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 386
Query: 612 QRELEAAEDRADVAESNLSLIRAKHRTFVT 641
+R+ + + + E +++K++ +T
Sbjct: 387 ERQNKELKVKLQEMEGT---VKSKYKASIT 413
Score = 50.4 bits (115), Expect = 2e-05
Identities = 64/331 (19%), Positives = 139/331 (41%), Gaps = 33/331 (9%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
K+ ++++ L A + ++ K + E + +KLQ Q+ + LD + ++ K+
Sbjct: 216 KKLEMDLKDLEAHI-DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKEN 274
Query: 359 SLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE--- 415
+L ++ ++Q +L AQ+ L E+ G AL KR +E
Sbjct: 275 EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARI 334
Query: 416 -QQYEESQTRVNELTVINVNLSSSKAKIEQ---ELAIVAA----------DYDEITKELR 461
Q EE + +IN L + +I+Q +L + + + KEL+
Sbjct: 335 AQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELK 394
Query: 462 I--------ADERYQRVQTELKHTVEHLHEE-----QERIVKIEAVKKSLEIEVKNISVR 508
+ +Y+ T L+ + L E+ +ER + V+++ E ++K++ ++
Sbjct: 395 VKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRT-EKKLKDVLLQ 453
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
+++ NA K K R+K ++ +L+E + RK +R+L++ +
Sbjct: 454 VDDERRNA-EQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADA 512
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+ +S L++ L + + +R + G
Sbjct: 513 MNREVSSLKNKLRRGDLPFVVPRRMARKGAG 543
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 144 bits (350), Expect = 7e-34
Identities = 110/506 (21%), Positives = 237/506 (46%), Gaps = 13/506 (2%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEE-SRRNVQNERMYKP 201
++ + ++ +LD ++++V E +QK K+I+ EE R +
Sbjct: 1426 QQELDDLTVDLD-HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1484
Query: 202 DFQASRTL-----VNRDYTNLSKNVLA--KALMESKAMNSCDSRVTESITETVRVRETSP 254
+R L ++ +K + A + LM SK + E + +
Sbjct: 1485 ALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEM 1544
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETVKQFD-DLSVYI-LNDSSKQTSI-EIEQLNAR 311
T + + EL A +++ L ++ QF+ DL N+ K+ I ++ +L A
Sbjct: 1545 RTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAE 1604
Query: 312 VVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
+ E E K ++ KKK++I + +LE ++ ANK ++ K ++K Q+ + Q +E
Sbjct: 1605 L-EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEE 1663
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+ Q ++++++SL E+ +++ + R +R EQ+ +E +
Sbjct: 1664 ARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG 1723
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI 491
L K ++E +A + + +E + + ++R+++ ++ L E+ K
Sbjct: 1724 KSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS 1783
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
+ ++ LE + K + +L+E+E K IS LEA+I +E +L++E + A K+
Sbjct: 1784 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL 1843
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
+R+ E++LKE+ +Q E+++++ ++ +EK + ++ KRQL E E + ++ R+
Sbjct: 1844 VRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKL 1903
Query: 612 QRELEAAEDRADVAESNLSLIRAKHR 637
QREL+ A + + +S ++ + R
Sbjct: 1904 QRELDDATEANEGLSREVSTLKNRLR 1929
Score = 77.0 bits (181), Expect = 2e-13
Identities = 84/384 (21%), Positives = 176/384 (45%), Gaps = 38/384 (9%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ +++E + +D + + + K I + ++++ E E K K+ + +I+ K ++ I
Sbjct: 979 KIKKMEEEILLLEDQNSKFIKEK-KLMEDRIAECSSQLAEEEEKAKN-LAKIRNKQEVMI 1036
Query: 335 TELELSLDVANKTNIDLQKTIKK-------QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQ 387
++LE L KT +L+K +K Q+ E+Q DE++ QL ++ A
Sbjct: 1037 SDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL 1096
Query: 388 RR--------------IQSLTGEVEEIRGNYE-------QALRVKRSVEQQYEESQTRVN 426
R ++ L ++ E++ ++E +A + KR + ++ E +T +
Sbjct: 1097 ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELE 1156
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDEITK--ELRIADERYQRVQTELKHTVEHLHEE 484
+ + K EQE+A + +E TK E +I D R QR T L+ E L +
Sbjct: 1157 DTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR-QRHATALEELSEQLEQA 1215
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEV-EANAIVGGKRIISKLEARIKDMELELDEEKR 543
+ +E K+ LE + K ++ ++ + + A KR KL+A+++++ ++ E R
Sbjct: 1216 KRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR--KKLDAQVQELHAKVSEGDR 1273
Query: 544 RHAETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
E + K + +L V EE ++K I +D+ SQ + + L E+
Sbjct: 1274 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQ-LQDTQELLQEETRQKL 1332
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+R+R+ + E + +++ + E
Sbjct: 1333 NLSSRIRQLEEEKNSLQEQQEEEE 1356
Score = 75.4 bits (177), Expect = 6e-13
Identities = 76/389 (19%), Positives = 180/389 (46%), Gaps = 24/389 (6%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ ELK+ +++ + D ++ + +E+L+ ++ +A+ + K+ + + K+ L+
Sbjct: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK-RFKANLEKNKQGLETDN 1233
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
EL + V + + + KK Q+ E+ E R ++ Q + +++
Sbjct: 1234 KELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVS 1293
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
+EE + + S+E Q +++Q + E T +NLSS ++E+E + +
Sbjct: 1294 TLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQE 1353
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E + + +++ +Q++L T + + ++ I +E KK L + + +S RLEE +A
Sbjct: 1354 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE-KA 1412
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
A ++ ++L+ + D+ ++LD ++ + L KK+++ +++ ++K+IS
Sbjct: 1413 LAYDKLEKTKNRLQQELDDLTVDLDHQR----QVASNLEKKQKKFDQLL----AEEKSIS 1464
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRA 634
+ Y + E +++ T+ R LE A + + E +RA
Sbjct: 1465 -------------ARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1511
Query: 635 KHRTFVTTSTVPGSQVYLVQES-RALSSE 662
+++ G V+ +++S RAL +
Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/253 (19%), Positives = 120/253 (47%), Gaps = 5/253 (1%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ +LQ ++ + + + GE+EE+ ++Q L K + +Q + E +
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
L++ K ++E+ L + + +E + +I +++Q ++ E L EE+ K++
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 493 AVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK 550
K + E ++K + + L E + + + K++ +E RI + +L EE+ + K
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKL---MEDRIAECSSQLAEEEEKAKNLAK 1027
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
I K+E + ++ + ++++K L+ + K + + + Q+AE + + ++ +
Sbjct: 1028 IRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAK 1087
Query: 611 FQRELEAAEDRAD 623
+ EL+ A R D
Sbjct: 1088 KEEELQGALARGD 1100
Score = 66.9 bits (156), Expect = 2e-10
Identities = 81/428 (18%), Positives = 183/428 (42%), Gaps = 29/428 (6%)
Query: 251 ETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNA 310
+ P V R EL A D L + + + +++ + Q +E + + A
Sbjct: 840 KVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEM------ERKHQQLLEEKNILA 893
Query: 311 RVVEAETKLKSEVTRI-------KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
++AET+L +E + K++L+ + +LE ++ + N LQ KK +
Sbjct: 894 EQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+++ DE + Q + A+ +I+ + E+ + + ++ K+ +E + E +
Sbjct: 954 DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITK-------ELRIADERYQRVQTELKH 476
++ E NL AKI + ++ +D +E K EL A + T+L+
Sbjct: 1014 QLAEEEEKAKNL----AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD 1069
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
+ L + + + K++ KK E++ E + N +++ +L+A+I +++
Sbjct: 1070 QIAELQAQIDEL-KLQLAKKEEELQGALARGDDETLHKN---NALKVVRELQAQIAELQE 1125
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
+ + EK + K R +L+ + + E+ + Q+ K Q+V+ K+ L E
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185
Query: 597 QEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
+ + + +R R LE ++ + A+ + + + T + +V ++Q+
Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1245
Query: 656 SRALSSER 663
+A S +
Sbjct: 1246 VKAESEHK 1253
Score = 54.8 bits (126), Expect = 9e-07
Identities = 99/493 (20%), Positives = 214/493 (43%), Gaps = 59/493 (11%)
Query: 147 QEIEKELDLYEKEVN-LGSELRQKAAMYRGKSAKAIAQTLLEESR-----RNVQNERMYK 200
+++ L+ +K+ + L +E + +A Y + +A A+ +E++ R ++ K
Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 201 PDFQASRTLVNRDYTNL--SKNVLAKALME-SKAMNSCDSRVTESITETVRVRETSPTT- 256
+F+ + D +L SK+ + K + E K+ + + +V E T+ + + T
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 257 -CVVRINTELPAIDNSYLNQL------NELKET--VKQFDDLSVYILND---------SS 298
+R+ + A+ + L NE K+ +KQ +L + ++ S
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1619
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
K+ I+++ L A++ EA K + EV + +KLQ Q+ + + L+ A + ++ K+
Sbjct: 1620 KKMEIDLKDLEAQI-EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Query: 359 SLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR------ 412
+L ++ ++Q +L + A++ L E+ L KR
Sbjct: 1679 EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARI 1738
Query: 413 -SVEQQYEESQTRVNEL------TVINVNLSSSKAKIEQELAIVAAD----YDEITKELR 461
+E++ EE Q+ + L T + V+ +++ E+ A + + + KEL+
Sbjct: 1739 AQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELK 1798
Query: 462 IADERYQ-RVQTELKHTVE-------HLHEEQERIVKIEAVKKSL----EIEVKNISVRL 509
+ + V+++ K T+ L E+ E+ K A L E ++K I +++
Sbjct: 1799 AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQV 1858
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
E+ +A K + K AR+K ++ +L+E + RK +R+L + E
Sbjct: 1859 EDERRHADQY-KEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1917
Query: 570 QKNISLLQDSLEK 582
+ +S L++ L +
Sbjct: 1918 SREVSTLKNRLRR 1930
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 144 bits (350), Expect = 7e-34
Identities = 110/506 (21%), Positives = 237/506 (46%), Gaps = 13/506 (2%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEE-SRRNVQNERMYKP 201
++ + ++ +LD ++++V E +QK K+I+ EE R +
Sbjct: 1426 QQELDDLTVDLD-HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1484
Query: 202 DFQASRTL-----VNRDYTNLSKNVLA--KALMESKAMNSCDSRVTESITETVRVRETSP 254
+R L ++ +K + A + LM SK + E + +
Sbjct: 1485 ALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEM 1544
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETVKQFD-DLSVYI-LNDSSKQTSI-EIEQLNAR 311
T + + EL A +++ L ++ QF+ DL N+ K+ I ++ +L A
Sbjct: 1545 RTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAE 1604
Query: 312 VVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
+ E E K ++ KKK++I + +LE ++ ANK ++ K ++K Q+ + Q +E
Sbjct: 1605 L-EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEE 1663
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+ Q ++++++SL E+ +++ + R +R EQ+ +E +
Sbjct: 1664 ARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG 1723
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI 491
L K ++E +A + + +E + + ++R+++ ++ L E+ K
Sbjct: 1724 KSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS 1783
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
+ ++ LE + K + +L+E+E K IS LEA+I +E +L++E + A K+
Sbjct: 1784 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL 1843
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
+R+ E++LKE+ +Q E+++++ ++ +EK + ++ KRQL E E + ++ R+
Sbjct: 1844 VRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKL 1903
Query: 612 QRELEAAEDRADVAESNLSLIRAKHR 637
QREL+ A + + +S ++ + R
Sbjct: 1904 QRELDDATEANEGLSREVSTLKNRLR 1929
Score = 77.0 bits (181), Expect = 2e-13
Identities = 84/384 (21%), Positives = 176/384 (45%), Gaps = 38/384 (9%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ +++E + +D + + + K I + ++++ E E K K+ + +I+ K ++ I
Sbjct: 979 KIKKMEEEILLLEDQNSKFIKEK-KLMEDRIAECSSQLAEEEEKAKN-LAKIRNKQEVMI 1036
Query: 335 TELELSLDVANKTNIDLQKTIKK-------QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQ 387
++LE L KT +L+K +K Q+ E+Q DE++ QL ++ A
Sbjct: 1037 SDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL 1096
Query: 388 RR--------------IQSLTGEVEEIRGNYE-------QALRVKRSVEQQYEESQTRVN 426
R ++ L ++ E++ ++E +A + KR + ++ E +T +
Sbjct: 1097 ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELE 1156
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDEITK--ELRIADERYQRVQTELKHTVEHLHEE 484
+ + K EQE+A + +E TK E +I D R QR T L+ E L +
Sbjct: 1157 DTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR-QRHATALEELSEQLEQA 1215
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEV-EANAIVGGKRIISKLEARIKDMELELDEEKR 543
+ +E K+ LE + K ++ ++ + + A KR KL+A+++++ ++ E R
Sbjct: 1216 KRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR--KKLDAQVQELHAKVSEGDR 1273
Query: 544 RHAETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
E + K + +L V EE ++K I +D+ SQ + + L E+
Sbjct: 1274 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQ-LQDTQELLQEETRQKL 1332
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+R+R+ + E + +++ + E
Sbjct: 1333 NLSSRIRQLEEEKNSLQEQQEEEE 1356
Score = 75.4 bits (177), Expect = 6e-13
Identities = 76/389 (19%), Positives = 180/389 (46%), Gaps = 24/389 (6%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ ELK+ +++ + D ++ + +E+L+ ++ +A+ + K+ + + K+ L+
Sbjct: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK-RFKANLEKNKQGLETDN 1233
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
EL + V + + + KK Q+ E+ E R ++ Q + +++
Sbjct: 1234 KELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVS 1293
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
+EE + + S+E Q +++Q + E T +NLSS ++E+E + +
Sbjct: 1294 TLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQE 1353
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E + + +++ +Q++L T + + ++ I +E KK L + + +S RLEE +A
Sbjct: 1354 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE-KA 1412
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
A ++ ++L+ + D+ ++LD ++ + L KK+++ +++ ++K+IS
Sbjct: 1413 LAYDKLEKTKNRLQQELDDLTVDLDHQR----QVASNLEKKQKKFDQLL----AEEKSIS 1464
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRA 634
+ Y + E +++ T+ R LE A + + E +RA
Sbjct: 1465 -------------ARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1511
Query: 635 KHRTFVTTSTVPGSQVYLVQES-RALSSE 662
+++ G V+ +++S RAL +
Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/253 (19%), Positives = 120/253 (47%), Gaps = 5/253 (1%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ +LQ ++ + + + GE+EE+ ++Q L K + +Q + E +
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
L++ K ++E+ L + + +E + +I +++Q ++ E L EE+ K++
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 493 AVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK 550
K + E ++K + + L E + + + K++ +E RI + +L EE+ + K
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKL---MEDRIAECSSQLAEEEEKAKNLAK 1027
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
I K+E + ++ + ++++K L+ + K + + + Q+AE + + ++ +
Sbjct: 1028 IRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAK 1087
Query: 611 FQRELEAAEDRAD 623
+ EL+ A R D
Sbjct: 1088 KEEELQGALARGD 1100
Score = 66.9 bits (156), Expect = 2e-10
Identities = 81/428 (18%), Positives = 183/428 (42%), Gaps = 29/428 (6%)
Query: 251 ETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNA 310
+ P V R EL A D L + + + +++ + Q +E + + A
Sbjct: 840 KVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEM------ERKHQQLLEEKNILA 893
Query: 311 RVVEAETKLKSEVTRI-------KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
++AET+L +E + K++L+ + +LE ++ + N LQ KK +
Sbjct: 894 EQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+++ DE + Q + A+ +I+ + E+ + + ++ K+ +E + E +
Sbjct: 954 DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITK-------ELRIADERYQRVQTELKH 476
++ E NL AKI + ++ +D +E K EL A + T+L+
Sbjct: 1014 QLAEEEEKAKNL----AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD 1069
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
+ L + + + K++ KK E++ E + N +++ +L+A+I +++
Sbjct: 1070 QIAELQAQIDEL-KLQLAKKEEELQGALARGDDETLHKN---NALKVVRELQAQIAELQE 1125
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
+ + EK + K R +L+ + + E+ + Q+ K Q+V+ K+ L E
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185
Query: 597 QEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
+ + + +R R LE ++ + A+ + + + T + +V ++Q+
Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1245
Query: 656 SRALSSER 663
+A S +
Sbjct: 1246 VKAESEHK 1253
Score = 54.8 bits (126), Expect = 9e-07
Identities = 99/493 (20%), Positives = 214/493 (43%), Gaps = 59/493 (11%)
Query: 147 QEIEKELDLYEKEVN-LGSELRQKAAMYRGKSAKAIAQTLLEESR-----RNVQNERMYK 200
+++ L+ +K+ + L +E + +A Y + +A A+ +E++ R ++ K
Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 201 PDFQASRTLVNRDYTNL--SKNVLAKALME-SKAMNSCDSRVTESITETVRVRETSPTT- 256
+F+ + D +L SK+ + K + E K+ + + +V E T+ + + T
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 257 -CVVRINTELPAIDNSYLNQL------NELKET--VKQFDDLSVYILND---------SS 298
+R+ + A+ + L NE K+ +KQ +L + ++ S
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1619
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
K+ I+++ L A++ EA K + EV + +KLQ Q+ + + L+ A + ++ K+
Sbjct: 1620 KKMEIDLKDLEAQI-EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Query: 359 SLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR------ 412
+L ++ ++Q +L + A++ L E+ L KR
Sbjct: 1679 EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARI 1738
Query: 413 -SVEQQYEESQTRVNEL------TVINVNLSSSKAKIEQELAIVAAD----YDEITKELR 461
+E++ EE Q+ + L T + V+ +++ E+ A + + + KEL+
Sbjct: 1739 AQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELK 1798
Query: 462 IADERYQ-RVQTELKHTVE-------HLHEEQERIVKIEAVKKSL----EIEVKNISVRL 509
+ + V+++ K T+ L E+ E+ K A L E ++K I +++
Sbjct: 1799 AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQV 1858
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
E+ +A K + K AR+K ++ +L+E + RK +R+L + E
Sbjct: 1859 EDERRHADQY-KEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1917
Query: 570 QKNISLLQDSLEK 582
+ +S L++ L +
Sbjct: 1918 SREVSTLKNRLRR 1930
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 144 bits (350), Expect = 7e-34
Identities = 114/509 (22%), Positives = 238/509 (46%), Gaps = 15/509 (2%)
Query: 143 KKRMQEIEKEL--DL-YEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEE-SRRNVQNERM 198
K R+Q+ +L DL ++++V E +QK K+I+ EE R +
Sbjct: 1422 KNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK 1481
Query: 199 YKPDFQASRTL-----VNRDYTNLSKNVLA--KALMESKAMNSCDSRVTESITETVRVRE 251
+R L ++ +K + A + LM SK + E + +
Sbjct: 1482 ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV 1541
Query: 252 TSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFD-DLSVYI-LNDSSKQTSI-EIEQL 308
T + + EL A +++ L ++ QF+ DL N+ K+ I ++ +L
Sbjct: 1542 EEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVREL 1601
Query: 309 NARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
A + E E K ++ KKK++I + +LE ++ ANK ++ K ++K Q+ + Q
Sbjct: 1602 EAEL-EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRE 1660
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E + Q ++++++SL E+ +++ + R +R EQ+ +E +
Sbjct: 1661 LEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 1720
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
L K ++E +A + + +E + + ++R+++ ++ L E+
Sbjct: 1721 ASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAA 1780
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
K + ++ LE + K + +L+E+E K IS LEA+I +E +L++E + A
Sbjct: 1781 QKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAA 1840
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
K++R+ E++LKE+ +Q E+++++ ++ +EK + ++ KRQL E E + ++
Sbjct: 1841 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 1900
Query: 609 RRFQRELEAAEDRADVAESNLSLIRAKHR 637
R+ QREL+ A + + +S ++ + R
Sbjct: 1901 RKLQRELDDATEANEGLSREVSTLKNRLR 1929
Score = 77.0 bits (181), Expect = 2e-13
Identities = 84/384 (21%), Positives = 176/384 (45%), Gaps = 38/384 (9%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ +++E + +D + + + K I + ++++ E E K K+ + +I+ K ++ I
Sbjct: 979 KIKKMEEEILLLEDQNSKFIKEK-KLMEDRIAECSSQLAEEEEKAKN-LAKIRNKQEVMI 1036
Query: 335 TELELSLDVANKTNIDLQKTIKK-------QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQ 387
++LE L KT +L+K +K Q+ E+Q DE++ QL ++ A
Sbjct: 1037 SDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL 1096
Query: 388 RR--------------IQSLTGEVEEIRGNYE-------QALRVKRSVEQQYEESQTRVN 426
R ++ L ++ E++ ++E +A + KR + ++ E +T +
Sbjct: 1097 ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELE 1156
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDEITK--ELRIADERYQRVQTELKHTVEHLHEE 484
+ + K EQE+A + +E TK E +I D R QR T L+ E L +
Sbjct: 1157 DTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR-QRHATALEELSEQLEQA 1215
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEV-EANAIVGGKRIISKLEARIKDMELELDEEKR 543
+ +E K+ LE + K ++ ++ + + A KR KL+A+++++ ++ E R
Sbjct: 1216 KRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR--KKLDAQVQELHAKVSEGDR 1273
Query: 544 RHAETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
E + K + +L V EE ++K I +D+ SQ + + L E+
Sbjct: 1274 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQ-LQDTQELLQEETRQKL 1332
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+R+R+ + E + +++ + E
Sbjct: 1333 NLSSRIRQLEEEKNSLQEQQEEEE 1356
Score = 73.3 bits (172), Expect = 2e-12
Identities = 76/389 (19%), Positives = 179/389 (46%), Gaps = 24/389 (6%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ ELK+ +++ + D ++ + +E+L+ ++ +A+ + K+ + + K+ L+
Sbjct: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK-RFKANLEKNKQGLETDN 1233
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
EL + V + + + KK Q+ E+ E R ++ Q + +++
Sbjct: 1234 KELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVS 1293
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
+EE + + S+E Q +++Q + E T +NLSS ++E+E + +
Sbjct: 1294 TLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQE 1353
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E + + +++ +Q++L T + + ++ I +E KK L + + +S RLEE +A
Sbjct: 1354 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE-KA 1412
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
A ++ ++L+ D+ ++LD ++ + L KK+++ +++ ++K+IS
Sbjct: 1413 LAYDKLEKTKNRLQQEPDDLTVDLDHQR----QVASNLEKKQKKFDQLL----AEEKSIS 1464
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRA 634
+ Y + E +++ T+ R LE A + + E +RA
Sbjct: 1465 -------------ARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1511
Query: 635 KHRTFVTTSTVPGSQVYLVQES-RALSSE 662
+++ G V+ +++S RAL +
Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQ 1540
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/253 (19%), Positives = 120/253 (47%), Gaps = 5/253 (1%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ +LQ ++ + + + GE+EE+ ++Q L K + +Q + E +
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
L++ K ++E+ L + + +E + +I +++Q ++ E L EE+ K++
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 493 AVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK 550
K + E ++K + + L E + + + K++ +E RI + +L EE+ + K
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKL---MEDRIAECSSQLAEEEEKAKNLAK 1027
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
I K+E + ++ + ++++K L+ + K + + + Q+AE + + ++ +
Sbjct: 1028 IRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAK 1087
Query: 611 FQRELEAAEDRAD 623
+ EL+ A R D
Sbjct: 1088 KEEELQGALARGD 1100
Score = 66.9 bits (156), Expect = 2e-10
Identities = 81/428 (18%), Positives = 183/428 (42%), Gaps = 29/428 (6%)
Query: 251 ETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNA 310
+ P V R EL A D L + + + +++ + Q +E + + A
Sbjct: 840 KVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEM------ERKHQQLLEEKNILA 893
Query: 311 RVVEAETKLKSEVTRI-------KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
++AET+L +E + K++L+ + +LE ++ + N LQ KK +
Sbjct: 894 EQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 953
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+++ DE + Q + A+ +I+ + E+ + + ++ K+ +E + E +
Sbjct: 954 DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1013
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITK-------ELRIADERYQRVQTELKH 476
++ E NL AKI + ++ +D +E K EL A + T+L+
Sbjct: 1014 QLAEEEEKAKNL----AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD 1069
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
+ L + + + K++ KK E++ E + N +++ +L+A+I +++
Sbjct: 1070 QIAELQAQIDEL-KLQLAKKEEELQGALARGDDETLHKN---NALKVVRELQAQIAELQE 1125
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
+ + EK + K R +L+ + + E+ + Q+ K Q+V+ K+ L E
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185
Query: 597 QEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
+ + + +R R LE ++ + A+ + + + T + +V ++Q+
Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1245
Query: 656 SRALSSER 663
+A S +
Sbjct: 1246 VKAESEHK 1253
Score = 54.8 bits (126), Expect = 9e-07
Identities = 99/493 (20%), Positives = 214/493 (43%), Gaps = 59/493 (11%)
Query: 147 QEIEKELDLYEKEVN-LGSELRQKAAMYRGKSAKAIAQTLLEESR-----RNVQNERMYK 200
+++ L+ +K+ + L +E + +A Y + +A A+ +E++ R ++ K
Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 201 PDFQASRTLVNRDYTNL--SKNVLAKALME-SKAMNSCDSRVTESITETVRVRETSPTT- 256
+F+ + D +L SK+ + K + E K+ + + +V E T+ + + T
Sbjct: 1500 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Query: 257 -CVVRINTELPAIDNSYLNQL------NELKET--VKQFDDLSVYILND---------SS 298
+R+ + A+ + L NE K+ +KQ +L + ++ S
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1619
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
K+ I+++ L A++ EA K + EV + +KLQ Q+ + + L+ A + ++ K+
Sbjct: 1620 KKMEIDLKDLEAQI-EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Query: 359 SLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR------ 412
+L ++ ++Q +L + A++ L E+ L KR
Sbjct: 1679 EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARI 1738
Query: 413 -SVEQQYEESQTRVNEL------TVINVNLSSSKAKIEQELAIVAAD----YDEITKELR 461
+E++ EE Q+ + L T + V+ +++ E+ A + + + KEL+
Sbjct: 1739 AQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELK 1798
Query: 462 IADERYQ-RVQTELKHTVE-------HLHEEQERIVKIEAVKKSL----EIEVKNISVRL 509
+ + V+++ K T+ L E+ E+ K A L E ++K I +++
Sbjct: 1799 AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQV 1858
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
E+ +A K + K AR+K ++ +L+E + RK +R+L + E
Sbjct: 1859 EDERRHADQY-KEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1917
Query: 570 QKNISLLQDSLEK 582
+ +S L++ L +
Sbjct: 1918 SREVSTLKNRLRR 1930
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 144 bits (350), Expect = 7e-34
Identities = 110/506 (21%), Positives = 237/506 (46%), Gaps = 13/506 (2%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEE-SRRNVQNERMYKP 201
++ + ++ +LD ++++V E +QK K+I+ EE R +
Sbjct: 1468 QQELDDLTVDLD-HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1526
Query: 202 DFQASRTL-----VNRDYTNLSKNVLA--KALMESKAMNSCDSRVTESITETVRVRETSP 254
+R L ++ +K + A + LM SK + E + +
Sbjct: 1527 ALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEM 1586
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETVKQFD-DLSVYI-LNDSSKQTSI-EIEQLNAR 311
T + + EL A +++ L ++ QF+ DL N+ K+ I ++ +L A
Sbjct: 1587 RTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAE 1646
Query: 312 VVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
+ E E K ++ KKK++I + +LE ++ ANK ++ K ++K Q+ + Q +E
Sbjct: 1647 L-EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEE 1705
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+ Q ++++++SL E+ +++ + R +R EQ+ +E +
Sbjct: 1706 ARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG 1765
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI 491
L K ++E +A + + +E + + ++R+++ ++ L E+ K
Sbjct: 1766 KSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS 1825
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
+ ++ LE + K + +L+E+E K IS LEA+I +E +L++E + A K+
Sbjct: 1826 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL 1885
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
+R+ E++LKE+ +Q E+++++ ++ +EK + ++ KRQL E E + ++ R+
Sbjct: 1886 VRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKL 1945
Query: 612 QRELEAAEDRADVAESNLSLIRAKHR 637
QREL+ A + + +S ++ + R
Sbjct: 1946 QRELDDATEANEGLSREVSTLKNRLR 1971
Score = 77.0 bits (181), Expect = 2e-13
Identities = 84/384 (21%), Positives = 176/384 (45%), Gaps = 38/384 (9%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ +++E + +D + + + K I + ++++ E E K K+ + +I+ K ++ I
Sbjct: 1021 KIKKMEEEILLLEDQNSKFIKEK-KLMEDRIAECSSQLAEEEEKAKN-LAKIRNKQEVMI 1078
Query: 335 TELELSLDVANKTNIDLQKTIKK-------QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQ 387
++LE L KT +L+K +K Q+ E+Q DE++ QL ++ A
Sbjct: 1079 SDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL 1138
Query: 388 RR--------------IQSLTGEVEEIRGNYE-------QALRVKRSVEQQYEESQTRVN 426
R ++ L ++ E++ ++E +A + KR + ++ E +T +
Sbjct: 1139 ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELE 1198
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDEITK--ELRIADERYQRVQTELKHTVEHLHEE 484
+ + K EQE+A + +E TK E +I D R QR T L+ E L +
Sbjct: 1199 DTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR-QRHATALEELSEQLEQA 1257
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEV-EANAIVGGKRIISKLEARIKDMELELDEEKR 543
+ +E K+ LE + K ++ ++ + + A KR KL+A+++++ ++ E R
Sbjct: 1258 KRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR--KKLDAQVQELHAKVSEGDR 1315
Query: 544 RHAETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
E + K + +L V EE ++K I +D+ SQ + + L E+
Sbjct: 1316 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQ-LQDTQELLQEETRQKL 1374
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+R+R+ + E + +++ + E
Sbjct: 1375 NLSSRIRQLEEEKNSLQEQQEEEE 1398
Score = 75.4 bits (177), Expect = 6e-13
Identities = 76/389 (19%), Positives = 180/389 (46%), Gaps = 24/389 (6%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ ELK+ +++ + D ++ + +E+L+ ++ +A+ + K+ + + K+ L+
Sbjct: 1217 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK-RFKANLEKNKQGLETDN 1275
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
EL + V + + + KK Q+ E+ E R ++ Q + +++
Sbjct: 1276 KELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVS 1335
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
+EE + + S+E Q +++Q + E T +NLSS ++E+E + +
Sbjct: 1336 TLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQE 1395
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E + + +++ +Q++L T + + ++ I +E KK L + + +S RLEE +A
Sbjct: 1396 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE-KA 1454
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
A ++ ++L+ + D+ ++LD ++ + L KK+++ +++ ++K+IS
Sbjct: 1455 LAYDKLEKTKNRLQQELDDLTVDLDHQR----QVASNLEKKQKKFDQLL----AEEKSIS 1506
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRA 634
+ Y + E +++ T+ R LE A + + E +RA
Sbjct: 1507 -------------ARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1553
Query: 635 KHRTFVTTSTVPGSQVYLVQES-RALSSE 662
+++ G V+ +++S RAL +
Sbjct: 1554 DMEDLMSSKDDVGKNVHELEKSKRALEQQ 1582
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/253 (19%), Positives = 120/253 (47%), Gaps = 5/253 (1%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ +LQ ++ + + + GE+EE+ ++Q L K + +Q + E +
Sbjct: 893 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 952
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
L++ K ++E+ L + + +E + +I +++Q ++ E L EE+ K++
Sbjct: 953 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 1012
Query: 493 AVKKSLEIEVKNI--SVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK 550
K + E ++K + + L E + + + K++ +E RI + +L EE+ + K
Sbjct: 1013 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKL---MEDRIAECSSQLAEEEEKAKNLAK 1069
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
I K+E + ++ + ++++K L+ + K + + + Q+AE + + ++ +
Sbjct: 1070 IRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAK 1129
Query: 611 FQRELEAAEDRAD 623
+ EL+ A R D
Sbjct: 1130 KEEELQGALARGD 1142
Score = 66.9 bits (156), Expect = 2e-10
Identities = 81/428 (18%), Positives = 183/428 (42%), Gaps = 29/428 (6%)
Query: 251 ETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNA 310
+ P V R EL A D L + + + +++ + Q +E + + A
Sbjct: 882 KVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEM------ERKHQQLLEEKNILA 935
Query: 311 RVVEAETKLKSEVTRI-------KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
++AET+L +E + K++L+ + +LE ++ + N LQ KK +
Sbjct: 936 EQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ 995
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+++ DE + Q + A+ +I+ + E+ + + ++ K+ +E + E +
Sbjct: 996 DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSS 1055
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITK-------ELRIADERYQRVQTELKH 476
++ E NL AKI + ++ +D +E K EL A + T+L+
Sbjct: 1056 QLAEEEEKAKNL----AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD 1111
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
+ L + + + K++ KK E++ E + N +++ +L+A+I +++
Sbjct: 1112 QIAELQAQIDEL-KLQLAKKEEELQGALARGDDETLHKN---NALKVVRELQAQIAELQE 1167
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
+ + EK + K R +L+ + + E+ + Q+ K Q+V+ K+ L E
Sbjct: 1168 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1227
Query: 597 QEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
+ + + +R R LE ++ + A+ + + + T + +V ++Q+
Sbjct: 1228 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1287
Query: 656 SRALSSER 663
+A S +
Sbjct: 1288 VKAESEHK 1295
Score = 54.8 bits (126), Expect = 9e-07
Identities = 99/493 (20%), Positives = 214/493 (43%), Gaps = 59/493 (11%)
Query: 147 QEIEKELDLYEKEVN-LGSELRQKAAMYRGKSAKAIAQTLLEESR-----RNVQNERMYK 200
+++ L+ +K+ + L +E + +A Y + +A A+ +E++ R ++ K
Sbjct: 1482 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1541
Query: 201 PDFQASRTLVNRDYTNL--SKNVLAKALME-SKAMNSCDSRVTESITETVRVRETSPTT- 256
+F+ + D +L SK+ + K + E K+ + + +V E T+ + + T
Sbjct: 1542 EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1601
Query: 257 -CVVRINTELPAIDNSYLNQL------NELKET--VKQFDDLSVYILND---------SS 298
+R+ + A+ + L NE K+ +KQ +L + ++ S
Sbjct: 1602 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1661
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
K+ I+++ L A++ EA K + EV + +KLQ Q+ + + L+ A + ++ K+
Sbjct: 1662 KKMEIDLKDLEAQI-EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1720
Query: 359 SLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR------ 412
+L ++ ++Q +L + A++ L E+ L KR
Sbjct: 1721 EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARI 1780
Query: 413 -SVEQQYEESQTRVNEL------TVINVNLSSSKAKIEQELAIVAAD----YDEITKELR 461
+E++ EE Q+ + L T + V+ +++ E+ A + + + KEL+
Sbjct: 1781 AQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELK 1840
Query: 462 IADERYQ-RVQTELKHTVE-------HLHEEQERIVKIEAVKKSL----EIEVKNISVRL 509
+ + V+++ K T+ L E+ E+ K A L E ++K I +++
Sbjct: 1841 AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQV 1900
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
E+ +A K + K AR+K ++ +L+E + RK +R+L + E
Sbjct: 1901 EDERRHADQY-KEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGL 1959
Query: 570 QKNISLLQDSLEK 582
+ +S L++ L +
Sbjct: 1960 SREVSTLKNRLRR 1972
>BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein.
Length = 471
Score = 144 bits (349), Expect = 9e-34
Identities = 90/385 (23%), Positives = 194/385 (50%), Gaps = 4/385 (1%)
Query: 256 TCVVRINTELPAIDNSYLNQLNELKETVKQFD-DLSVYI-LNDSSKQTSI-EIEQLNARV 312
T + + EL A +++ L ++ QF+ DL N+ K+ I ++ +L A +
Sbjct: 41 TQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAEL 100
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
E E K ++ KKK++I + +LE ++ ANK ++ K ++K Q+ + Q +E
Sbjct: 101 -EDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEA 159
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ Q ++++++SL E+ +++ + R +R EQ+ +E +
Sbjct: 160 RASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGK 219
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
L K ++E +A + + +E + + ++R+++ ++ L E+ K +
Sbjct: 220 SALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSD 279
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
++ LE + K + +L+E+E K IS LEA+I +E +L++E + A K++
Sbjct: 280 NARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLV 339
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQ 612
R+ E++LKE+ +Q E+++++ ++ +EK + ++ KRQL E E + ++ R+ Q
Sbjct: 340 RRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQ 399
Query: 613 RELEAAEDRADVAESNLSLIRAKHR 637
REL+ A + + +S ++ + R
Sbjct: 400 RELDDATEANEGLSREVSTLKNRLR 424
Score = 78.6 bits (185), Expect = 7e-14
Identities = 60/288 (20%), Positives = 135/288 (46%), Gaps = 2/288 (0%)
Query: 328 KKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQ 387
K+L+ + +L S D K +L+K+ + Q+ E++T +E++ +LQ T D +
Sbjct: 2 KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE 61
Query: 388 RRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
+Q++ + E +++ EQ KR + +Q E + + + +SK K+E +L
Sbjct: 62 VNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDL 121
Query: 447 AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNIS 506
+ A + K ++ +++Q ++K L E + +I A K E ++K++
Sbjct: 122 KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLE 181
Query: 507 VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQC 566
+ +++ + +R E ++ E+ + + R+ E ++ ++ +
Sbjct: 182 AEILQLQ-EELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEEL 240
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
EE+Q N+ LL D KT+ +V +LA + +Q+S ++ +R+
Sbjct: 241 EEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQ 288
Score = 53.6 bits (123), Expect = 2e-06
Identities = 67/315 (21%), Positives = 139/315 (44%), Gaps = 31/315 (9%)
Query: 297 SSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK 356
S K+ I+++ L A++ EA K + EV + +KLQ Q+ + + L+ A + ++ K
Sbjct: 113 SKKKMEIDLKDLEAQI-EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSK 171
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR---- 412
+ +L ++ ++Q +L + A++ L E+ L KR
Sbjct: 172 ESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEA 231
Query: 413 ---SVEQQYEESQTRVNEL------TVINVNLSSSKAKIEQELAIVAAD----YDEITKE 459
+E++ EE Q+ + L T + V+ +++ E+ A + + + KE
Sbjct: 232 RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE 291
Query: 460 LRIADERYQ-RVQTELKHTVE-------HLHEEQERIVKIEAVKKSL----EIEVKNISV 507
L+ + + V+++ K T+ L E+ E+ K A L E ++K I +
Sbjct: 292 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 351
Query: 508 RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCE 567
++E+ +A K + K AR+K ++ +L+E + RK +R+L + E
Sbjct: 352 QVEDERRHADQY-KEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANE 410
Query: 568 EDQKNISLLQDSLEK 582
+ +S L++ L +
Sbjct: 411 GLSREVSTLKNRLRR 425
>BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein.
Length = 638
Score = 144 bits (348), Expect = 1e-33
Identities = 121/535 (22%), Positives = 248/535 (46%), Gaps = 15/535 (2%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAK---AIAQTLLEESRRNVQNERM 198
+++ QE++ E++ L S L +K + A+ A+ + + E R +
Sbjct: 82 RRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER 141
Query: 199 YKPDFQASRTLVNRDYTNLSKNVLAKALM-ESKAMNSCDSRVTESITE---TVRVRETSP 254
+R L +AL E +A+ S V +S+ E RV E +
Sbjct: 142 EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAA 201
Query: 255 TTC---VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEI-EQLNA 310
V + EL A +++ L +L + +K + + +++ ++ ++ +QL
Sbjct: 202 NDLRAQVTELEDELTAAEDAKL-RLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 260
Query: 311 RVVEAETKLKSEVTRI--KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
VE + + K + +KKL+ ++ EL+ + A + + K ++K Q+ E+
Sbjct: 261 AEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWRE 320
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E + + Q +++R++ L EV ++ + R +R +Q +E V
Sbjct: 321 VEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 380
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+ + K ++E L + + +E + ++RY+++ +++ L E+
Sbjct: 381 NLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFS 440
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
K E+ ++ LE +++ + RL E +A A K I+ LE+++ E +L++E R +
Sbjct: 441 AKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILS 500
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
K++R+ E++LKEV++Q EE+++ L+D LEK + +V KRQL E E + ++
Sbjct: 501 GKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 560
Query: 609 RRFQRELEAAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQVYLVQESRALSSE 662
RR QRELE + A+ ++ +R + R +T +T QV+ ++E A E
Sbjct: 561 RRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 615
Score = 41.1 bits (92), Expect = 0.012
Identities = 61/281 (21%), Positives = 111/281 (39%), Gaps = 15/281 (5%)
Query: 361 QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEE 420
QL E + R+LQ Q +RR + G +E E+A +R ++ E
Sbjct: 11 QLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEA----GEEA---RRRAAREAEA 63
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYD---EITKELRIADERYQRVQTELKHT 477
R+ E T L + +++QEL D + ++ L ++ ++ E K
Sbjct: 64 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAA 123
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE 537
V EE+ER EA + E +++ LEE E A +R L A ++ +
Sbjct: 124 VLRAVEERER---AEAEGREREARALSLTRALEE-EQEAREELERQNRALRAELEALLSS 179
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ-LAE 596
D+ + E + R E+ ++ Q E + ++ +D+ + V K Q +
Sbjct: 180 KDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERD 239
Query: 597 QEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+G + R R+ ++L AE D +L A +
Sbjct: 240 LQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARK 280
Score = 37.5 bits (83), Expect = 0.15
Identities = 44/235 (18%), Positives = 100/235 (42%), Gaps = 6/235 (2%)
Query: 406 QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
+A ++ +E++ + EL LS + + E+E + A + + R A+
Sbjct: 4 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 63
Query: 466 RYQRVQTELKHTVEHLHEEQERI-VKIEAVKKSLEIEVKNIS-VRLEEVEANAIVGGKR- 522
QR+ E TV+ L + R+ +++ LE + + +S + ++ + + ++ ++
Sbjct: 64 LTQRL-AEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 122
Query: 523 -IISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
++ +E R + E E E + R + L +++ +E+ Q + + L S +
Sbjct: 123 AVLRAVEER-ERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKD 181
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
+ V +R E + +V + EL AAED E + ++ +H
Sbjct: 182 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 236
Score = 32.7 bits (71), Expect = 4.3
Identities = 24/113 (21%), Positives = 50/113 (44%)
Query: 527 LEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
+EA + +L+EE + L+ + QL E + EE+ + +++ + +++
Sbjct: 1 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 60
Query: 587 VSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
++LAE+ + RR Q+EL+ A + +S + K R F
Sbjct: 61 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 113
>AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain protein.
Length = 1995
Score = 144 bits (348), Expect = 1e-33
Identities = 121/535 (22%), Positives = 248/535 (46%), Gaps = 15/535 (2%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAK---AIAQTLLEESRRNVQNERM 198
+++ QE++ E++ L S L +K + A+ A+ + + E R +
Sbjct: 1439 RRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER 1498
Query: 199 YKPDFQASRTLVNRDYTNLSKNVLAKALM-ESKAMNSCDSRVTESITE---TVRVRETSP 254
+R L +AL E +A+ S V +S+ E RV E +
Sbjct: 1499 EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAA 1558
Query: 255 TTC---VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEI-EQLNA 310
V + EL A +++ L +L + +K + + +++ ++ ++ +QL
Sbjct: 1559 NDLRAQVTELEDELTAAEDAKL-RLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 1617
Query: 311 RVVEAETKLKSEVTRI--KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
VE + + K + +KKL+ ++ EL+ + A + + K ++K Q+ E+
Sbjct: 1618 AEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWRE 1677
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E + + Q +++R++ L EV ++ + R +R +Q +E V
Sbjct: 1678 VEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1737
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+ + K ++E L + + +E + ++RY+++ +++ L E+
Sbjct: 1738 NLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFS 1797
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
K E+ ++ LE +++ + RL E +A A K I+ LE+++ E +L++E R +
Sbjct: 1798 AKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILS 1857
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
K++R+ E++LKEV++Q EE+++ L+D LEK + +V KRQL E E + ++
Sbjct: 1858 GKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1917
Query: 609 RRFQRELEAAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQVYLVQESRALSSE 662
RR QRELE + A+ ++ +R + R +T +T QV+ ++E A E
Sbjct: 1918 RRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1972
Score = 68.5 bits (160), Expect = 7e-11
Identities = 75/332 (22%), Positives = 149/332 (44%), Gaps = 18/332 (5%)
Query: 315 AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
A TK + + + ++L+ ELE +LD N Q+ K+ ++TE++ +E R
Sbjct: 1150 ARTKAEKQRRDLGEELEALRGELEDTLDSTNAQ----QELRSKREQEVTELKKTLEEETR 1205
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+ + + + QR Q+L GE+ E EQA R K + E+ + V+EL +
Sbjct: 1206 IHEAAVQE--LRQRHGQAL-GELAE---QLEQARRGKGAWEKTRLALEAEVSELRAELSS 1259
Query: 435 LSSSKAKIEQELAIVAADYDEIT-------KELRIADERYQRVQTELKHTVEHLHEEQER 487
L +++ + EQ + E+ + A E+ QR Q EL++ L+E + +
Sbjct: 1260 LQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESK 1319
Query: 488 IVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
+++ S E ++ + L+E + G R+ + +EA + +L+EE
Sbjct: 1320 TIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRA-MEAEAAGLREQLEEEAAARER 1378
Query: 548 TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
+ L+ + QL E + EE+ + +++ + +++ ++LAE+ +
Sbjct: 1379 AGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERG 1438
Query: 608 VRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
RR Q+EL+ A + +S + K R F
Sbjct: 1439 RRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1470
Score = 67.3 bits (157), Expect = 2e-10
Identities = 73/365 (20%), Positives = 161/365 (44%), Gaps = 11/365 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ ELK+T+++ + + + ++ + +L A +E + K + + L+ ++
Sbjct: 1192 EVTELKKTLEEETRIHEAAVQELRQRHGQALGEL-AEQLEQARRGKGAWEKTRLALEAEV 1250
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
+EL L + ++ ++ LQL E+Q + +R ++ AQ +++++
Sbjct: 1251 SELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVS 1310
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
G + E + + S E Q ++Q + E T + L S +E E A + +
Sbjct: 1311 GALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE 1370
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E A Q Q +L EE + E ++ E + ++ RL E +
Sbjct: 1371 EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE-KT 1429
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL----KEVIIQCEEDQ 570
+ +R +L+ + D ++L E++R+ T++ ++K QL K +++ E++
Sbjct: 1430 ETVDRLERGRRRLQQELDDATMDL-EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER 1488
Query: 571 KNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA-AEDRADVAESNL 629
+ + E+ ++ +S+ R L E++ ++ + R + ELEA + DV +S
Sbjct: 1489 ERAE--AEGREREARALSL-TRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVH 1545
Query: 630 SLIRA 634
L RA
Sbjct: 1546 ELERA 1550
Score = 49.6 bits (113), Expect = 3e-05
Identities = 54/283 (19%), Positives = 120/283 (42%), Gaps = 13/283 (4%)
Query: 350 DLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALR 409
+L+K ++ + +E+Q E Q++ + Q G + +Q+ E+ G Q L+
Sbjct: 1069 ELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLK 1128
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE-RYQ 468
R + E+Q + V + + +EL + + ++ E R +
Sbjct: 1129 SLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSK 1188
Query: 469 RVQ--TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISK 526
R Q TELK T+E E + ++ +++ + ++ +LE+ K ++
Sbjct: 1189 REQEVTELKKTLE--EETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLA- 1245
Query: 527 LEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
LEA + ++ EL + E + R+ E QL+EV + + ++ + + ++K
Sbjct: 1246 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGER-------ARAEAAEK 1298
Query: 587 VSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+ + +L G ++ ++ R +EL + E + A+ L
Sbjct: 1299 LQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL 1341
Score = 45.2 bits (102), Expect = 7e-04
Identities = 56/268 (20%), Positives = 124/268 (46%), Gaps = 18/268 (6%)
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+ +V+ LQVT Q V Q R Q L +V+E++ + + + Q EE + R+ E
Sbjct: 855 FTKVKPLLQVTR-QDEVLQARAQELQ-KVQELQQQSAREVGELQGRVAQLEEERARLAEQ 912
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKEL--RIADERY--QRVQTELKHTVEHLHEE 484
L + + LA + + + EL R+ +E +++QTE K +H+ E
Sbjct: 913 LRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQEL 972
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV--GGKRIISKLEA--RIKDMELELDE 540
+ + E ++ L++E ++++ E + ++ +SK + +I +
Sbjct: 973 EAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKSGSCWKIVWPSSHPRQ 1032
Query: 541 EKRRHAETIKI-----LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
+RR I +R + + ++ + + E+ ++ + L+ L+ S ++ + Q+
Sbjct: 1033 LRRRRRSRASISYGSNMRPQSQTWRDRLRKEEKGRQELEKLKRRLDGESSEL---QEQMV 1089
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRAD 623
EQ+ +++ ++ R + EL+AA RA+
Sbjct: 1090 EQQQRAEELRAQLGRKEEELQAALARAE 1117
>AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein.
Length = 1571
Score = 144 bits (348), Expect = 1e-33
Identities = 121/535 (22%), Positives = 248/535 (46%), Gaps = 15/535 (2%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAK---AIAQTLLEESRRNVQNERM 198
+++ QE++ E++ L S L +K + A+ A+ + + E R +
Sbjct: 1015 RRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER 1074
Query: 199 YKPDFQASRTLVNRDYTNLSKNVLAKALM-ESKAMNSCDSRVTESITE---TVRVRETSP 254
+R L +AL E +A+ S V +S+ E RV E +
Sbjct: 1075 EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAA 1134
Query: 255 TTC---VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEI-EQLNA 310
V + EL A +++ L +L + +K + + +++ ++ ++ +QL
Sbjct: 1135 NDLRAQVTELEDELTAAEDAKL-RLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 1193
Query: 311 RVVEAETKLKSEVTRI--KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
VE + + K + +KKL+ ++ EL+ + A + + K ++K Q+ E+
Sbjct: 1194 AEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWRE 1253
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E + + Q +++R++ L EV ++ + R +R +Q +E V
Sbjct: 1254 VEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1313
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+ + K ++E L + + +E + ++RY+++ +++ L E+
Sbjct: 1314 NLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFS 1373
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
K E+ ++ LE +++ + RL E +A A K I+ LE+++ E +L++E R +
Sbjct: 1374 AKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILS 1433
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
K++R+ E++LKEV++Q EE+++ L+D LEK + +V KRQL E E + ++
Sbjct: 1434 GKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1493
Query: 609 RRFQRELEAAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQVYLVQESRALSSE 662
RR QRELE + A+ ++ +R + R +T +T QV+ ++E A E
Sbjct: 1494 RRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1548
Score = 68.5 bits (160), Expect = 7e-11
Identities = 75/332 (22%), Positives = 149/332 (44%), Gaps = 18/332 (5%)
Query: 315 AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
A TK + + + ++L+ ELE +LD N Q+ K+ ++TE++ +E R
Sbjct: 726 ARTKAEKQRRDLGEELEALRGELEDTLDSTNAQ----QELRSKREQEVTELKKTLEEETR 781
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+ + + + QR Q+L GE+ E EQA R K + E+ + V+EL +
Sbjct: 782 IHEAAVQE--LRQRHGQAL-GELAE---QLEQARRGKGAWEKTRLALEAEVSELRAELSS 835
Query: 435 LSSSKAKIEQELAIVAADYDEIT-------KELRIADERYQRVQTELKHTVEHLHEEQER 487
L +++ + EQ + E+ + A E+ QR Q EL++ L+E + +
Sbjct: 836 LQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESK 895
Query: 488 IVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
+++ S E ++ + L+E + G R+ + +EA + +L+EE
Sbjct: 896 TIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRA-MEAEAAGLREQLEEEAAARER 954
Query: 548 TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
+ L+ + QL E + EE+ + +++ + +++ ++LAE+ +
Sbjct: 955 AGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERG 1014
Query: 608 VRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
RR Q+EL+ A + +S + K R F
Sbjct: 1015 RRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1046
Score = 67.3 bits (157), Expect = 2e-10
Identities = 73/365 (20%), Positives = 161/365 (44%), Gaps = 11/365 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++ ELK+T+++ + + + ++ + +L A +E + K + + L+ ++
Sbjct: 768 EVTELKKTLEEETRIHEAAVQELRQRHGQALGEL-AEQLEQARRGKGAWEKTRLALEAEV 826
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
+EL L + ++ ++ LQL E+Q + +R ++ AQ +++++
Sbjct: 827 SELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVS 886
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
G + E + + S E Q ++Q + E T + L S +E E A + +
Sbjct: 887 GALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE 946
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
E A Q Q +L EE + E ++ E + ++ RL E +
Sbjct: 947 EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE-KT 1005
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL----KEVIIQCEEDQ 570
+ +R +L+ + D ++L E++R+ T++ ++K QL K +++ E++
Sbjct: 1006 ETVDRLERGRRRLQQELDDATMDL-EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER 1064
Query: 571 KNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA-AEDRADVAESNL 629
+ + E+ ++ +S+ R L E++ ++ + R + ELEA + DV +S
Sbjct: 1065 ERAE--AEGREREARALSL-TRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVH 1121
Query: 630 SLIRA 634
L RA
Sbjct: 1122 ELERA 1126
Score = 65.3 bits (152), Expect = 7e-10
Identities = 95/491 (19%), Positives = 207/491 (42%), Gaps = 28/491 (5%)
Query: 150 EKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTL 209
++ L +E+ EL+Q++A G+ +AQ LEE R + + + + A
Sbjct: 444 DEVLQARAQELQKVQELQQQSAREVGELQGRVAQ--LEEERARLAEQLRAEAELCAEAE- 500
Query: 210 VNRDYTNLSKNVLAKALMESKAMNSCDSRVTESI-TETVRVRETSPTTCVVRINTELPAI 268
R K L + E +A + + + TE R+++ + E A
Sbjct: 501 ETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQEL-EAHLEAEEGAR 559
Query: 269 DNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE-------IEQLNARVVEAETKLKS 321
L ++ + +K+F++ + +L D + + S E + + +++ E E K+KS
Sbjct: 560 QKLQLEKVTT-EAKMKKFEE-DLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 617
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
+ +++ K + I ++E L K +L+K ++ + +E+Q E Q++ +
Sbjct: 618 -LNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 676
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
Q G + +Q+ E+ G Q L+ R + E+Q + V +
Sbjct: 677 QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRD 736
Query: 442 IEQELAIVAADYDEITKELRIADE-RYQRVQ--TELKHTVEHLHEEQERIVKIEAVKKSL 498
+ +EL + + ++ E R +R Q TELK T+E E + ++ +++
Sbjct: 737 LGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE--EETRIHEAAVQELRQRH 794
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
+ ++ +LE+ K ++ LEA + ++ EL + E + R+ E Q
Sbjct: 795 GQALGELAEQLEQARRGKGAWEKTRLA-LEAEVSELRAELSSLQTARQEGEQRRRRLELQ 853
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
L+EV + + ++ + + ++K+ + +L G ++ ++ R +EL +
Sbjct: 854 LQEVQGRAGDGER-------ARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 906
Query: 619 EDRADVAESNL 629
E + A+ L
Sbjct: 907 EAQLHDAQELL 917
>AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens
cDNA FLJ13881 fis, clone THYRO1001458, moderately
similar to MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 545
Score = 142 bits (345), Expect = 3e-33
Identities = 120/527 (22%), Positives = 255/527 (48%), Gaps = 25/527 (4%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKA-AMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+K+ ++ ++ L + V E R++A A R + A+A++ T R ++ E+ +
Sbjct: 14 EKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLT------RALEEEQEARE 67
Query: 202 DFQASRTLVNRDYTNL--SKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
+ + + + L SK+ + K++ E + +C RV E +R + V
Sbjct: 68 ELERQNRALRAELEALLSSKDDVGKSVHELE--RAC--RVAEQAANDLRAQ-------VT 116
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEI-EQLNARVVEAETK 318
+ EL A +++ L +L + +K + + +++ ++ ++ +QL VE + +
Sbjct: 117 ELEDELTAAEDAKL-RLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEE 175
Query: 319 LKSEVTRI--KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
K + +KKL+ ++ EL+ + A + + K ++K Q+ E+ +E +
Sbjct: 176 RKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSR 235
Query: 377 QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLS 436
+ Q +++R++ L EV ++ + R +R +Q +E V + +
Sbjct: 236 EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAIL 295
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKK 496
K ++E L + + +E + ++RY+++ +++ L E+ K E+ ++
Sbjct: 296 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 355
Query: 497 SLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKE 556
LE +++ + RL E +A A K I+ LE+++ E +L++E R + K++R+ E
Sbjct: 356 QLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAE 415
Query: 557 RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
++LKEV++Q EE+++ L+D LEK + +V KRQL E E + ++ RR QRELE
Sbjct: 416 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 475
Query: 617 AAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQVYLVQESRALSSE 662
+ A+ ++ +R + R +T +T QV+ ++E A E
Sbjct: 476 DVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 522
>BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein.
Length = 483
Score = 142 bits (343), Expect = 5e-33
Identities = 97/409 (23%), Positives = 203/409 (49%), Gaps = 5/409 (1%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEI-EQLNARVVEAE 316
V + EL A +++ L +L + +K + + +++ ++ ++ +QL VE +
Sbjct: 53 VTELEDELTAAEDAKL-RLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERD 111
Query: 317 TKLKSEVTRI--KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
+ K + +KKL+ ++ EL+ + A + + K ++K Q+ E+ +E +
Sbjct: 112 EERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRT 171
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+ Q +++R++ L EV ++ + R +R +Q +E V +
Sbjct: 172 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 231
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
+ K ++E L + + +E + ++RY+++ +++ L E+ K E+
Sbjct: 232 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG 291
Query: 495 KKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRK 554
++ LE +++ + RL E +A A K I+ LE+++ E +L++E R + K++R+
Sbjct: 292 RQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRR 351
Query: 555 KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
E++LKEV++Q EE+++ L+D LEK + +V KRQL E E + ++ RR QRE
Sbjct: 352 AEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 411
Query: 615 LEAAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQVYLVQESRALSSE 662
LE + A+ ++ +R + R +T +T QV+ ++E A E
Sbjct: 412 LEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 460
Score = 52.4 bits (120), Expect = 5e-06
Identities = 70/310 (22%), Positives = 133/310 (42%), Gaps = 24/310 (7%)
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV----QRQL-------QV 378
L+ Q+TELE L A + L+ T++ Q DE +RQL +V
Sbjct: 49 LRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV 108
Query: 379 TLD----QYGVAQRRIQSLTGEVEEIRGNY-------EQALRVKRSVEQQYEESQTRVNE 427
D Q +A + L GE+EE++ E+A++ R ++ Q +E V E
Sbjct: 109 ERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE 168
Query: 428 LTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQER 487
+ S + E+ L + A+ + +EL +D ++ Q + + +
Sbjct: 169 TRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS 228
Query: 488 IVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
I K+ LE + + LEE ++N+ + R KL +++ + EL E+ A+
Sbjct: 229 KAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR-YRKLLLQVESLTTELSAERSFSAK 287
Query: 548 TIKILRKKERQLKEVIIQC-EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
++ ERQ++E+ + EED + + ++ K++ + QL ++ S
Sbjct: 288 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGK 347
Query: 607 RVRRFQRELE 616
VRR ++ L+
Sbjct: 348 LVRRAEKRLK 357
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 132 bits (318), Expect = 5e-30
Identities = 103/435 (23%), Positives = 204/435 (46%), Gaps = 10/435 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 32 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 91
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 92 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 150
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 151 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 210
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 211 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 269
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 270 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 329
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 330 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 389
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 390 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 449
Query: 632 IRAKHRTFVTTSTVP 646
+++K R TS VP
Sbjct: 450 LKSKLRRGNETSFVP 464
Score = 92.3 bits (219), Expect = 5e-18
Identities = 64/306 (20%), Positives = 148/306 (48%), Gaps = 2/306 (0%)
Query: 310 ARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
AR +E + K E+ R K L+ ++ +L S D K +L+K+ + Q+ E++T
Sbjct: 15 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 74
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E++ +LQ T D + +Q+L G+ E +++ EQ +R +++Q E +T + +
Sbjct: 75 EELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 134
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+++K K+E +L + D K A ++ +++Q ++K L + +
Sbjct: 135 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 194
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
+I A K E + K++ L +++ + + +R + + +++ EL
Sbjct: 195 DEIFATAKENEKKAKSLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNAL 253
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
R+ E ++ ++ + EE+Q N+ + D + K +Q+ +LA + +Q++ +
Sbjct: 254 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 313
Query: 609 RRFQRE 614
++ +R+
Sbjct: 314 QQLERQ 319
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/287 (19%), Positives = 122/287 (42%), Gaps = 8/287 (2%)
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
R +E + E+ K+ + + LE L + ++ K+ L+ E+
Sbjct: 185 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 244
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELT 429
D+ + RI L E+EE +GN E + RV+++ +Q + S E +
Sbjct: 245 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 304
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
N S++ ++E++ + + E+ ++ +++ L+ + L E+ E+
Sbjct: 305 TAQKN-ESARQQLERQNKELRSKLHEMEGAVK---SKFKSTIAALEAKIAQLEEQVEQEA 360
Query: 490 KI-EAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELELDEEKRRHA 546
+ +A KSL+ + K + L +VE + K K AR+K ++ +L+E +
Sbjct: 361 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 420
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
RK +R+L E E + ++ L+ L + ++ + R+
Sbjct: 421 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRR 467
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 132 bits (318), Expect = 5e-30
Identities = 103/435 (23%), Positives = 204/435 (46%), Gaps = 10/435 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 1631
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 1632 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1691
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 1692 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 1750
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1810
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 1811 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1870
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 1871 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1930
Query: 632 IRAKHRTFVTTSTVP 646
+++K R TS VP
Sbjct: 1931 LKSKLRRGNETSFVP 1945
Score = 93.9 bits (223), Expect = 2e-18
Identities = 89/471 (18%), Positives = 209/471 (44%), Gaps = 15/471 (3%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+++++E+E + + + L E+ K + R S I L +S++ +Q+ +
Sbjct: 1344 KLRQLEEERNSLQDQ--LDEEMEAKQNLERHISTLNIQ---LSDSKKKLQDFASTVEALE 1398
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ ++ NL++ KA K + +R+ + + + V V + V + +
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDK-LEKTKNRLQQELDDLV-VDLDNQRQLVSNLEKK 1456
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
D + N + + D +K S+ AR +E + K E+
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL------ARALEEALEAKEELE 1510
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
R K L+ ++ +L S D K +L+K+ + Q+ E++T +E++ +LQ T D
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1570
Query: 385 VAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ +Q+L G+ E +++ EQ +R +++Q E +T + + +++K K+E
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+L + D K A ++ +++Q ++K L + + +I A K E + K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
++ L +++ + + +R + + +++ EL R+ E ++ ++
Sbjct: 1691 SLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 1749
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+ EE+Q N+ + D + K +Q+ +LA + +Q++ + ++ +R+
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800
Score = 81.8 bits (193), Expect = 7e-15
Identities = 73/359 (20%), Positives = 169/359 (47%), Gaps = 24/359 (6%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E+L ++ E + K+ + + K+ L+ + +L L V + +++ KK Q+ E
Sbjct: 1212 VEELTEQL-EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 1270
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+Q+ + +R D+ Q ++S+TG + E G + + S+ Q +++Q
Sbjct: 1271 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1330
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ E T +N+S+ ++E+E + DE + + + + +L + + L +
Sbjct: 1331 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1390
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ +E KK + E++N++ + EE +A A ++ ++L+ + D+ ++LD ++
Sbjct: 1391 ASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKLEKTKNRLQQELDDLVVDLDNQR-- 1447
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
+ + L KK+R+ +++ ++KNIS S Y + E +++
Sbjct: 1448 --QLVSNLEKKQRKFDQLL----AEEKNIS-------------SKYADERDRAEAEAREK 1488
Query: 605 VTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES-RALSSE 662
T+ R LE A + + E +++A+ V++ G V+ +++S RAL ++
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1547
Score = 79.0 bits (186), Expect = 5e-14
Identities = 58/267 (21%), Positives = 127/267 (47%), Gaps = 15/267 (5%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++Q D+ + R Q E++E+ + Q K +++Q + E +
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
V L++ K ++E+ L E+ L ++R Q++Q E K + + + +E++ + E
Sbjct: 918 VRLAAKKQELEEIL-------HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIV--GGKRIISK----LEARIKDMELELDEEKRRHA 546
A ++ L++E +++++E +V +SK LE RI D+ L EE+ +
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
K+ K E + E+ ++ ++++K+ L+ K S + Q+A+ + +
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090
Query: 607 RVRRFQRELEAAEDRAD--VAESNLSL 631
++ + + EL+AA R D +A+ N +L
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNAL 1117
Score = 72.5 bits (170), Expect = 4e-12
Identities = 87/353 (24%), Positives = 166/353 (47%), Gaps = 42/353 (11%)
Query: 317 TKLKS--EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
TK+K +VTR ++++Q + EL+ + + K +L++ +K S QLTE + +Q
Sbjct: 846 TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHS-QLTE---EKNLLQE 901
Query: 375 QLQVTLDQYGVAQR---RIQSLTGEVEEI-------------RGNYEQALRVKRS----- 413
QLQ + Y A+ R+ + E+EEI RG QA R K +
Sbjct: 902 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 961
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
+E+Q EE + +L + V + K+E E+ ++ ++++KE ++ +ER + T
Sbjct: 962 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT- 1020
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
+L EE+E+ + +K E + + VRL++ E + +++ KLE D
Sbjct: 1021 ------NLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQELEKLKRKLEGDASD 1073
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEED--QKNISLLQDSLEKTSQKVSIYK 591
++ + + + AE L KKE +L+ + + +++ QKN +L + + +S +
Sbjct: 1074 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL--KKIRELEGHISDLQ 1131
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAE-DRADVAESNLSL--IRAKHRTFVT 641
L + ++ + R ELEA + + D +S + +RAK VT
Sbjct: 1132 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1184
Score = 71.3 bits (167), Expect = 1e-11
Identities = 106/489 (21%), Positives = 211/489 (43%), Gaps = 42/489 (8%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q +R + ++ LDL E+++ RQK + + + I + E + QN ++ K
Sbjct: 949 QAERKKMAQQMLDL-EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK- 1006
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITET-VRVRETSPTTCVVR 260
R L+ ++L+ N LA+ ++K + ++ I+E VR+++ +
Sbjct: 1007 ----ERKLLEERISDLTTN-LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS----- 1056
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
EL + ++ E Q DL I + Q + + E+L A + + ++
Sbjct: 1057 -RQELEKLKRKLEGDASDFHE---QIADLQAQIA-ELKMQLAKKEEELQAALARLDDEIA 1111
Query: 321 SEVTRIKK--KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ +KK +L+ I++L+ LD +K + +L ++T E++ L
Sbjct: 1112 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT---ELEDTLDS 1168
Query: 379 TLDQYGVAQRRIQSLT----GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
T Q + +R Q +T EE R + Q +++ Q EE ++ + N
Sbjct: 1169 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1228
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L +K +E+E A +A ELR+ + Q V+ + K + E Q + E
Sbjct: 1229 LDKNKQTLEKENADLAG-------ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1281
Query: 495 K-------KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
+ L+ EV++++ L E E AI K + S L ++++D + L EE R+
Sbjct: 1282 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS-LSSQLQDTQELLQEETRQKLN 1340
Query: 548 TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
LR+ E + + Q +E+ + L+ + + ++S K++L + +
Sbjct: 1341 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG 1400
Query: 608 VRRFQRELE 616
+RFQ+E+E
Sbjct: 1401 KKRFQKEIE 1409
Score = 70.9 bits (166), Expect = 1e-11
Identities = 83/418 (19%), Positives = 172/418 (41%), Gaps = 12/418 (2%)
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTE--SITETVRVRETSPTTCVVRI 261
Q D +K KA E K + S++TE ++ + ET +
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK--QTSIEIEQLNARVVEAETKL 319
L A L+E++ +++ +D + + K Q +++E+ A KL
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+ E K + +I +LE + V + N L K K +++++ T+ E + + +
Sbjct: 977 QLE----KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ I L +++ + ++ ++KR +E + ++ +L L
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
AK E+EL A D+ + A ++ + ++ + E L E+ K E K+ L
Sbjct: 1093 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1152
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
E++ + LE+ ++ + + +K E + ++ LDEE R H ++ +R+K Q
Sbjct: 1153 EELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1211
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
E + E + + +L+K Q + LA + + Q+ V +++LEA
Sbjct: 1212 VE---ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1266
Score = 67.7 bits (158), Expect = 1e-10
Identities = 109/500 (21%), Positives = 208/500 (41%), Gaps = 37/500 (7%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKA-AMYRGKSAKAIAQTLLEE--SRRNVQNE----- 196
+MQ +KE +L L E+ QK A+ + + + L E+ S R +N+
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 197 RMYKPDFQASRTLVNR--DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSP 254
R + +A +T + D T + + AK E + T S V+
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETV-KQFDDLS--VYILNDSSKQTSIEIEQLNAR 311
V + +L + N L++ K+T+ K+ DL+ + +L + ++ + ++L A+
Sbjct: 1209 AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1267
Query: 312 VVEAETKL------KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
V E ++K ++E+ KLQ ++ + L+ A I L K + S QL +
Sbjct: 1268 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1327
Query: 366 QTHYDEVQRQ---LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
Q E RQ + L Q + +Q E E + N E+ + ++ Q +S+
Sbjct: 1328 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS---TLNIQLSDSK 1384
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ + L K + ++E+ + Y+E ++ R+Q EL V L
Sbjct: 1385 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1444
Query: 483 EEQERIVKIEAVKKSLE---IEVKNISVRL--EEVEANAIVGGKRIISKLEARIKDMELE 537
+++ + +E ++ + E KNIS + E A A K + AR + LE
Sbjct: 1445 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1504
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
EE R T K+L+ ++++++ ++ KN+ L+ S ++ K QL E
Sbjct: 1505 AKEELER---TNKMLKA---EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558
Query: 598 EGMSQQSVTRVRRFQRELEA 617
E Q + R + ++A
Sbjct: 1559 EDELQATEDAKLRLEVNMQA 1578
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/287 (19%), Positives = 122/287 (42%), Gaps = 8/287 (2%)
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
R +E + E+ K+ + + LE L + ++ K+ L+ E+
Sbjct: 1666 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 1725
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELT 429
D+ + RI L E+EE +GN E + RV+++ +Q + S E +
Sbjct: 1726 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 1785
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
N S++ ++E++ + + E+ ++ +++ L+ + L E+ E+
Sbjct: 1786 TAQKN-ESARQQLERQNKELRSKLHEMEGAVK---SKFKSTIAALEAKIAQLEEQVEQEA 1841
Query: 490 KI-EAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELELDEEKRRHA 546
+ +A KSL+ + K + L +VE + K K AR+K ++ +L+E +
Sbjct: 1842 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1901
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
RK +R+L E E + ++ L+ L + ++ + R+
Sbjct: 1902 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRR 1948
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 132 bits (318), Expect = 5e-30
Identities = 103/435 (23%), Positives = 204/435 (46%), Gaps = 10/435 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 156 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 215
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 216 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 274
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 275 DLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 334
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 335 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 393
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 394 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 453
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 454 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 513
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 514 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 573
Query: 632 IRAKHRTFVTTSTVP 646
+++K R TS VP
Sbjct: 574 LKSKLRRGNETSFVP 588
Score = 91.9 bits (218), Expect = 7e-18
Identities = 64/306 (20%), Positives = 147/306 (48%), Gaps = 2/306 (0%)
Query: 310 ARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
AR +E + K E+ R K L+ ++ +L S D K +L+K+ + Q+ E++T
Sbjct: 139 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 198
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E++ +LQ T D + +Q+L G+ E +++ EQ +R +++Q E +T + +
Sbjct: 199 EELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 258
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+++K K+E +L + D K A + +++Q ++K L + +
Sbjct: 259 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASR 318
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
+I A K E + K++ L +++ + + +R + + +++ EL
Sbjct: 319 DEIFATAKENEKKAKSLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNAL 377
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
R+ E ++ ++ + EE+Q N+ + D + K +Q+ +LA + +Q++ +
Sbjct: 378 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 437
Query: 609 RRFQRE 614
++ +R+
Sbjct: 438 QQLERQ 443
Score = 75.8 bits (178), Expect = 5e-13
Identities = 79/376 (21%), Positives = 172/376 (45%), Gaps = 14/376 (3%)
Query: 260 RINTELPAIDN--SYLNQLN-ELKETVKQFDDLS--VYILNDSSKQTSIEIEQLNARVVE 314
++N E+ A N +++ LN +L ++ K+ D + V L + K+ EIE L + E
Sbjct: 1 QLNEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-E 59
Query: 315 AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
+ ++ + K +LQ ++ +L + LD + +L+K +K L E + +
Sbjct: 60 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 119
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+ + + + SL +EE E+ R + ++ + E+ + +++
Sbjct: 120 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 179
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE-QERIVKIEA 493
L SK +E ++ + +E+ EL+ ++ R++ ++ + Q R + E
Sbjct: 180 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 494 VKKSLEIEVKNISVRLE-EVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
++ L+ ++ LE E + A+ + KLE +KD+EL+ D + E IK +
Sbjct: 240 KRRQLQRQLHEYETELEDERKQRALAAAAK--KKLEGDLKDLELQADSAIKGREEAIKHV 297
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE-QEGMSQQSVTRVRRF 611
RK + Q+K+ + E+ + + + + ++ +K + L + QE ++ + R R+
Sbjct: 298 RKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA--AAERARK- 354
Query: 612 QRELEAAEDRADVAES 627
Q +LE E ++A S
Sbjct: 355 QADLEKEELAEELASS 370
Score = 58.0 bits (134), Expect = 1e-07
Identities = 58/279 (20%), Positives = 121/279 (43%), Gaps = 17/279 (6%)
Query: 361 QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEE 420
QL E ++R + Q +++++Q VE + ++ + ++ QQYEE
Sbjct: 1 QLNEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE 60
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYD---EITKELRIADERYQRVQTELKHT 477
++L +K +++QEL + D D ++ L ++ ++ E K+
Sbjct: 61 KAAAYDKL-------EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNI 113
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE-VEANAIVGGKRIISKLEARIKDMEL 536
+E++R EA + E + +++ LEE +EA + +R L+A ++D+
Sbjct: 114 SSKYADERDR---AEAEAREKETKALSLARALEEALEAKEEL--ERTNKMLKAEMEDLVS 168
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL-A 595
D+ + E K R E Q++E+ Q EE + + +D+ + + K Q
Sbjct: 169 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 228
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRA 634
+ + +Q+ + R+ QR+L E + +L A
Sbjct: 229 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 267
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/287 (19%), Positives = 122/287 (42%), Gaps = 8/287 (2%)
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
R +E + E+ K+ + + LE L + ++ K+ L+ E+
Sbjct: 309 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 368
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELT 429
D+ + RI L E+EE +GN E + RV+++ +Q + S E +
Sbjct: 369 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 428
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
N S++ ++E++ + + E+ ++ +++ L+ + L E+ E+
Sbjct: 429 TAQKN-ESARQQLERQNKELRSKLHEMEGAVK---SKFKSTIAALEAKIAQLEEQVEQEA 484
Query: 490 KI-EAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELELDEEKRRHA 546
+ +A KSL+ + K + L +VE + K K AR+K ++ +L+E +
Sbjct: 485 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 544
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
RK +R+L E E + ++ L+ L + ++ + R+
Sbjct: 545 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRR 591
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 132 bits (318), Expect = 5e-30
Identities = 103/435 (23%), Positives = 204/435 (46%), Gaps = 10/435 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 1391 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1450
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 1451 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 1509
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 1510 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1569
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 1570 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 1628
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 1629 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1688
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 1689 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1748
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 1749 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1808
Query: 632 IRAKHRTFVTTSTVP 646
+++K R TS VP
Sbjct: 1809 LKSKLRRGNETSFVP 1823
Score = 93.9 bits (223), Expect = 2e-18
Identities = 89/471 (18%), Positives = 209/471 (44%), Gaps = 15/471 (3%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+++++E+E + + + L E+ K + R S I L +S++ +Q+ +
Sbjct: 1222 KLRQLEEERNSLQDQ--LDEEMEAKQNLERHISTLNIQ---LSDSKKKLQDFASTVEALE 1276
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ ++ NL++ KA K + +R+ + + + V V + V + +
Sbjct: 1277 EGKKRFQKEIENLTQQYEEKAAAYDK-LEKTKNRLQQELDDLV-VDLDNQRQLVSNLEKK 1334
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
D + N + + D +K S+ AR +E + K E+
Sbjct: 1335 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL------ARALEEALEAKEELE 1388
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
R K L+ ++ +L S D K +L+K+ + Q+ E++T +E++ +LQ T D
Sbjct: 1389 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1448
Query: 385 VAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ +Q+L G+ E +++ EQ +R +++Q E +T + + +++K K+E
Sbjct: 1449 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1508
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+L + D K A ++ +++Q ++K L + + +I A K E + K
Sbjct: 1509 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1568
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
++ L +++ + + +R + + +++ EL R+ E ++ ++
Sbjct: 1569 SLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 1627
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+ EE+Q N+ + D + K +Q+ +LA + +Q++ + ++ +R+
Sbjct: 1628 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1678
Score = 81.8 bits (193), Expect = 7e-15
Identities = 73/359 (20%), Positives = 169/359 (47%), Gaps = 24/359 (6%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E+L ++ E + K+ + + K+ L+ + +L L V + +++ KK Q+ E
Sbjct: 1090 VEELTEQL-EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 1148
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+Q+ + +R D+ Q ++S+TG + E G + + S+ Q +++Q
Sbjct: 1149 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1208
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ E T +N+S+ ++E+E + DE + + + + +L + + L +
Sbjct: 1209 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1268
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ +E KK + E++N++ + EE +A A ++ ++L+ + D+ ++LD ++
Sbjct: 1269 ASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKLEKTKNRLQQELDDLVVDLDNQR-- 1325
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
+ + L KK+R+ +++ ++KNIS S Y + E +++
Sbjct: 1326 --QLVSNLEKKQRKFDQLL----AEEKNIS-------------SKYADERDRAEAEAREK 1366
Query: 605 VTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES-RALSSE 662
T+ R LE A + + E +++A+ V++ G V+ +++S RAL ++
Sbjct: 1367 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1425
Score = 79.0 bits (186), Expect = 5e-14
Identities = 58/267 (21%), Positives = 127/267 (47%), Gaps = 15/267 (5%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++Q D+ + R Q E++E+ + Q K +++Q + E +
Sbjct: 736 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 795
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
V L++ K ++E+ L E+ L ++R Q++Q E K + + + +E++ + E
Sbjct: 796 VRLAAKKQELEEIL-------HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 848
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIV--GGKRIISK----LEARIKDMELELDEEKRRHA 546
A ++ L++E +++++E +V +SK LE RI D+ L EE+ +
Sbjct: 849 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 908
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
K+ K E + E+ ++ ++++K+ L+ K S + Q+A+ + +
Sbjct: 909 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 968
Query: 607 RVRRFQRELEAAEDRAD--VAESNLSL 631
++ + + EL+AA R D +A+ N +L
Sbjct: 969 QLAKKEEELQAALARLDDEIAQKNNAL 995
Score = 72.5 bits (170), Expect = 4e-12
Identities = 87/353 (24%), Positives = 166/353 (47%), Gaps = 42/353 (11%)
Query: 317 TKLKS--EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
TK+K +VTR ++++Q + EL+ + + K +L++ +K S QLTE + +Q
Sbjct: 724 TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHS-QLTE---EKNLLQE 779
Query: 375 QLQVTLDQYGVAQR---RIQSLTGEVEEI-------------RGNYEQALRVKRS----- 413
QLQ + Y A+ R+ + E+EEI RG QA R K +
Sbjct: 780 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 839
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
+E+Q EE + +L + V + K+E E+ ++ ++++KE ++ +ER + T
Sbjct: 840 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT- 898
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
+L EE+E+ + +K E + + VRL++ E + +++ KLE D
Sbjct: 899 ------NLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQELEKLKRKLEGDASD 951
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEED--QKNISLLQDSLEKTSQKVSIYK 591
++ + + + AE L KKE +L+ + + +++ QKN +L + + +S +
Sbjct: 952 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL--KKIRELEGHISDLQ 1009
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAE-DRADVAESNLSL--IRAKHRTFVT 641
L + ++ + R ELEA + + D +S + +RAK VT
Sbjct: 1010 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1062
Score = 71.3 bits (167), Expect = 1e-11
Identities = 106/489 (21%), Positives = 211/489 (43%), Gaps = 42/489 (8%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q +R + ++ LDL E+++ RQK + + + I + E + QN ++ K
Sbjct: 827 QAERKKMAQQMLDL-EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK- 884
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITET-VRVRETSPTTCVVR 260
R L+ ++L+ N LA+ ++K + ++ I+E VR+++ +
Sbjct: 885 ----ERKLLEERISDLTTN-LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS----- 934
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
EL + ++ E Q DL I + Q + + E+L A + + ++
Sbjct: 935 -RQELEKLKRKLEGDASDFHE---QIADLQAQIA-ELKMQLAKKEEELQAALARLDDEIA 989
Query: 321 SEVTRIKK--KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ +KK +L+ I++L+ LD +K + +L ++T E++ L
Sbjct: 990 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT---ELEDTLDS 1046
Query: 379 TLDQYGVAQRRIQSLT----GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
T Q + +R Q +T EE R + Q +++ Q EE ++ + N
Sbjct: 1047 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1106
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L +K +E+E A +A ELR+ + Q V+ + K + E Q + E
Sbjct: 1107 LDKNKQTLEKENADLAG-------ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1159
Query: 495 K-------KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
+ L+ EV++++ L E E AI K + S L ++++D + L EE R+
Sbjct: 1160 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS-LSSQLQDTQELLQEETRQKLN 1218
Query: 548 TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
LR+ E + + Q +E+ + L+ + + ++S K++L + +
Sbjct: 1219 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG 1278
Query: 608 VRRFQRELE 616
+RFQ+E+E
Sbjct: 1279 KKRFQKEIE 1287
Score = 70.9 bits (166), Expect = 1e-11
Identities = 83/418 (19%), Positives = 172/418 (41%), Gaps = 12/418 (2%)
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTE--SITETVRVRETSPTTCVVRI 261
Q D +K KA E K + S++TE ++ + ET +
Sbjct: 735 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 794
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK--QTSIEIEQLNARVVEAETKL 319
L A L+E++ +++ +D + + K Q +++E+ A KL
Sbjct: 795 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 854
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+ E K + +I +LE + V + N L K K +++++ T+ E + + +
Sbjct: 855 QLE----KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 910
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ I L +++ + ++ ++KR +E + ++ +L L
Sbjct: 911 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 970
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
AK E+EL A D+ + A ++ + ++ + E L E+ K E K+ L
Sbjct: 971 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1030
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
E++ + LE+ ++ + + +K E + ++ LDEE R H ++ +R+K Q
Sbjct: 1031 EELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1089
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
E + E + + +L+K Q + LA + + Q+ V +++LEA
Sbjct: 1090 VE---ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1144
Score = 67.7 bits (158), Expect = 1e-10
Identities = 109/500 (21%), Positives = 208/500 (41%), Gaps = 37/500 (7%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKA-AMYRGKSAKAIAQTLLEE--SRRNVQNE----- 196
+MQ +KE +L L E+ QK A+ + + + L E+ S R +N+
Sbjct: 967 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1026
Query: 197 RMYKPDFQASRTLVNR--DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSP 254
R + +A +T + D T + + AK E + T S V+
Sbjct: 1027 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1086
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETV-KQFDDLS--VYILNDSSKQTSIEIEQLNAR 311
V + +L + N L++ K+T+ K+ DL+ + +L + ++ + ++L A+
Sbjct: 1087 AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1145
Query: 312 VVEAETKL------KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
V E ++K ++E+ KLQ ++ + L+ A I L K + S QL +
Sbjct: 1146 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1205
Query: 366 QTHYDEVQRQ---LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
Q E RQ + L Q + +Q E E + N E+ + ++ Q +S+
Sbjct: 1206 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS---TLNIQLSDSK 1262
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ + L K + ++E+ + Y+E ++ R+Q EL V L
Sbjct: 1263 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1322
Query: 483 EEQERIVKIEAVKKSLE---IEVKNISVRL--EEVEANAIVGGKRIISKLEARIKDMELE 537
+++ + +E ++ + E KNIS + E A A K + AR + LE
Sbjct: 1323 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1382
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
EE R T K+L+ ++++++ ++ KN+ L+ S ++ K QL E
Sbjct: 1383 AKEELER---TNKMLKA---EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1436
Query: 598 EGMSQQSVTRVRRFQRELEA 617
E Q + R + ++A
Sbjct: 1437 EDELQATEDAKLRLEVNMQA 1456
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/287 (19%), Positives = 122/287 (42%), Gaps = 8/287 (2%)
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
R +E + E+ K+ + + LE L + ++ K+ L+ E+
Sbjct: 1544 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 1603
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELT 429
D+ + RI L E+EE +GN E + RV+++ +Q + S E +
Sbjct: 1604 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 1663
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
N S++ ++E++ + + E+ ++ +++ L+ + L E+ E+
Sbjct: 1664 TAQKN-ESARQQLERQNKELRSKLHEMEGAVK---SKFKSTIAALEAKIAQLEEQVEQEA 1719
Query: 490 KI-EAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELELDEEKRRHA 546
+ +A KSL+ + K + L +VE + K K AR+K ++ +L+E +
Sbjct: 1720 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1779
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
RK +R+L E E + ++ L+ L + ++ + R+
Sbjct: 1780 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRR 1826
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 132 bits (318), Expect = 5e-30
Identities = 103/435 (23%), Positives = 204/435 (46%), Gaps = 10/435 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 1518 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1577
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 1578 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 1636
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 1637 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1696
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 1697 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 1755
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 1756 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1815
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 1816 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1875
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 1876 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1935
Query: 632 IRAKHRTFVTTSTVP 646
+++K R TS VP
Sbjct: 1936 LKSKLRRGNETSFVP 1950
Score = 93.9 bits (223), Expect = 2e-18
Identities = 89/471 (18%), Positives = 209/471 (44%), Gaps = 15/471 (3%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+++++E+E + + + L E+ K + R S I L +S++ +Q+ +
Sbjct: 1349 KLRQLEEERNSLQDQ--LDEEMEAKQNLERHISTLNIQ---LSDSKKKLQDFASTVEALE 1403
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ ++ NL++ KA K + +R+ + + + V V + V + +
Sbjct: 1404 EGKKRFQKEIENLTQQYEEKAAAYDK-LEKTKNRLQQELDDLV-VDLDNQRQLVSNLEKK 1461
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
D + N + + D +K S+ AR +E + K E+
Sbjct: 1462 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL------ARALEEALEAKEELE 1515
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
R K L+ ++ +L S D K +L+K+ + Q+ E++T +E++ +LQ T D
Sbjct: 1516 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1575
Query: 385 VAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ +Q+L G+ E +++ EQ +R +++Q E +T + + +++K K+E
Sbjct: 1576 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1635
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+L + D K A ++ +++Q ++K L + + +I A K E + K
Sbjct: 1636 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1695
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
++ L +++ + + +R + + +++ EL R+ E ++ ++
Sbjct: 1696 SLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 1754
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+ EE+Q N+ + D + K +Q+ +LA + +Q++ + ++ +R+
Sbjct: 1755 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1805
Score = 81.8 bits (193), Expect = 7e-15
Identities = 73/359 (20%), Positives = 169/359 (47%), Gaps = 24/359 (6%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E+L ++ E + K+ + + K+ L+ + +L L V + +++ KK Q+ E
Sbjct: 1217 VEELTEQL-EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 1275
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+Q+ + +R D+ Q ++S+TG + E G + + S+ Q +++Q
Sbjct: 1276 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1335
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ E T +N+S+ ++E+E + DE + + + + +L + + L +
Sbjct: 1336 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1395
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ +E KK + E++N++ + EE +A A ++ ++L+ + D+ ++LD ++
Sbjct: 1396 ASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKLEKTKNRLQQELDDLVVDLDNQR-- 1452
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
+ + L KK+R+ +++ ++KNIS S Y + E +++
Sbjct: 1453 --QLVSNLEKKQRKFDQLL----AEEKNIS-------------SKYADERDRAEAEAREK 1493
Query: 605 VTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES-RALSSE 662
T+ R LE A + + E +++A+ V++ G V+ +++S RAL ++
Sbjct: 1494 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1552
Score = 79.0 bits (186), Expect = 5e-14
Identities = 58/267 (21%), Positives = 127/267 (47%), Gaps = 15/267 (5%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++Q D+ + R Q E++E+ + Q K +++Q + E +
Sbjct: 863 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 922
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
V L++ K ++E+ L E+ L ++R Q++Q E K + + + +E++ + E
Sbjct: 923 VRLAAKKQELEEIL-------HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 975
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIV--GGKRIISK----LEARIKDMELELDEEKRRHA 546
A ++ L++E +++++E +V +SK LE RI D+ L EE+ +
Sbjct: 976 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1035
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
K+ K E + E+ ++ ++++K+ L+ K S + Q+A+ + +
Sbjct: 1036 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1095
Query: 607 RVRRFQRELEAAEDRAD--VAESNLSL 631
++ + + EL+AA R D +A+ N +L
Sbjct: 1096 QLAKKEEELQAALARLDDEIAQKNNAL 1122
Score = 72.5 bits (170), Expect = 4e-12
Identities = 87/353 (24%), Positives = 166/353 (47%), Gaps = 42/353 (11%)
Query: 317 TKLKS--EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
TK+K +VTR ++++Q + EL+ + + K +L++ +K S QLTE + +Q
Sbjct: 851 TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHS-QLTE---EKNLLQE 906
Query: 375 QLQVTLDQYGVAQR---RIQSLTGEVEEI-------------RGNYEQALRVKRS----- 413
QLQ + Y A+ R+ + E+EEI RG QA R K +
Sbjct: 907 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 966
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
+E+Q EE + +L + V + K+E E+ ++ ++++KE ++ +ER + T
Sbjct: 967 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT- 1025
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
+L EE+E+ + +K E + + VRL++ E + +++ KLE D
Sbjct: 1026 ------NLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQELEKLKRKLEGDASD 1078
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEED--QKNISLLQDSLEKTSQKVSIYK 591
++ + + + AE L KKE +L+ + + +++ QKN +L + + +S +
Sbjct: 1079 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL--KKIRELEGHISDLQ 1136
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAE-DRADVAESNLSL--IRAKHRTFVT 641
L + ++ + R ELEA + + D +S + +RAK VT
Sbjct: 1137 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1189
Score = 71.3 bits (167), Expect = 1e-11
Identities = 106/489 (21%), Positives = 211/489 (43%), Gaps = 42/489 (8%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q +R + ++ LDL E+++ RQK + + + I + E + QN ++ K
Sbjct: 954 QAERKKMAQQMLDL-EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK- 1011
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITET-VRVRETSPTTCVVR 260
R L+ ++L+ N LA+ ++K + ++ I+E VR+++ +
Sbjct: 1012 ----ERKLLEERISDLTTN-LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS----- 1061
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
EL + ++ E Q DL I + Q + + E+L A + + ++
Sbjct: 1062 -RQELEKLKRKLEGDASDFHE---QIADLQAQIA-ELKMQLAKKEEELQAALARLDDEIA 1116
Query: 321 SEVTRIKK--KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ +KK +L+ I++L+ LD +K + +L ++T E++ L
Sbjct: 1117 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT---ELEDTLDS 1173
Query: 379 TLDQYGVAQRRIQSLT----GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
T Q + +R Q +T EE R + Q +++ Q EE ++ + N
Sbjct: 1174 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1233
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L +K +E+E A +A ELR+ + Q V+ + K + E Q + E
Sbjct: 1234 LDKNKQTLEKENADLAG-------ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1286
Query: 495 K-------KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
+ L+ EV++++ L E E AI K + S L ++++D + L EE R+
Sbjct: 1287 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS-LSSQLQDTQELLQEETRQKLN 1345
Query: 548 TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
LR+ E + + Q +E+ + L+ + + ++S K++L + +
Sbjct: 1346 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG 1405
Query: 608 VRRFQRELE 616
+RFQ+E+E
Sbjct: 1406 KKRFQKEIE 1414
Score = 70.9 bits (166), Expect = 1e-11
Identities = 83/418 (19%), Positives = 172/418 (41%), Gaps = 12/418 (2%)
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTE--SITETVRVRETSPTTCVVRI 261
Q D +K KA E K + S++TE ++ + ET +
Sbjct: 862 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 921
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK--QTSIEIEQLNARVVEAETKL 319
L A L+E++ +++ +D + + K Q +++E+ A KL
Sbjct: 922 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 981
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+ E K + +I +LE + V + N L K K +++++ T+ E + + +
Sbjct: 982 QLE----KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1037
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ I L +++ + ++ ++KR +E + ++ +L L
Sbjct: 1038 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1097
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
AK E+EL A D+ + A ++ + ++ + E L E+ K E K+ L
Sbjct: 1098 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1157
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
E++ + LE+ ++ + + +K E + ++ LDEE R H ++ +R+K Q
Sbjct: 1158 EELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1216
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
E + E + + +L+K Q + LA + + Q+ V +++LEA
Sbjct: 1217 VE---ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1271
Score = 67.7 bits (158), Expect = 1e-10
Identities = 109/500 (21%), Positives = 208/500 (41%), Gaps = 37/500 (7%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKA-AMYRGKSAKAIAQTLLEE--SRRNVQNE----- 196
+MQ +KE +L L E+ QK A+ + + + L E+ S R +N+
Sbjct: 1094 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1153
Query: 197 RMYKPDFQASRTLVNR--DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSP 254
R + +A +T + D T + + AK E + T S V+
Sbjct: 1154 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1213
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETV-KQFDDLS--VYILNDSSKQTSIEIEQLNAR 311
V + +L + N L++ K+T+ K+ DL+ + +L + ++ + ++L A+
Sbjct: 1214 AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1272
Query: 312 VVEAETKL------KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
V E ++K ++E+ KLQ ++ + L+ A I L K + S QL +
Sbjct: 1273 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1332
Query: 366 QTHYDEVQRQ---LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
Q E RQ + L Q + +Q E E + N E+ + ++ Q +S+
Sbjct: 1333 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS---TLNIQLSDSK 1389
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ + L K + ++E+ + Y+E ++ R+Q EL V L
Sbjct: 1390 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1449
Query: 483 EEQERIVKIEAVKKSLE---IEVKNISVRL--EEVEANAIVGGKRIISKLEARIKDMELE 537
+++ + +E ++ + E KNIS + E A A K + AR + LE
Sbjct: 1450 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1509
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
EE R T K+L+ ++++++ ++ KN+ L+ S ++ K QL E
Sbjct: 1510 AKEELER---TNKMLKA---EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1563
Query: 598 EGMSQQSVTRVRRFQRELEA 617
E Q + R + ++A
Sbjct: 1564 EDELQATEDAKLRLEVNMQA 1583
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/287 (19%), Positives = 122/287 (42%), Gaps = 8/287 (2%)
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
R +E + E+ K+ + + LE L + ++ K+ L+ E+
Sbjct: 1671 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 1730
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELT 429
D+ + RI L E+EE +GN E + RV+++ +Q + S E +
Sbjct: 1731 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 1790
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
N S++ ++E++ + + E+ ++ +++ L+ + L E+ E+
Sbjct: 1791 TAQKN-ESARQQLERQNKELRSKLHEMEGAVK---SKFKSTIAALEAKIAQLEEQVEQEA 1846
Query: 490 KI-EAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELELDEEKRRHA 546
+ +A KSL+ + K + L +VE + K K AR+K ++ +L+E +
Sbjct: 1847 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1906
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
RK +R+L E E + ++ L+ L + ++ + R+
Sbjct: 1907 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRR 1953
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 131 bits (316), Expect = 9e-30
Identities = 103/435 (23%), Positives = 204/435 (46%), Gaps = 10/435 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 415 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 474
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 475 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 533
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 534 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 593
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 594 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 652
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 653 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQQLERQNKELRSKLHE 712
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 713 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 772
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 773 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 832
Query: 632 IRAKHRTFVTTSTVP 646
+++K R TS VP
Sbjct: 833 LKSKLRRGNETSFVP 847
Score = 93.9 bits (223), Expect = 2e-18
Identities = 89/471 (18%), Positives = 209/471 (44%), Gaps = 15/471 (3%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+++++E+E + + + L E+ K + R S I L +S++ +Q+ +
Sbjct: 246 KLRQLEEERNSLQDQ--LDEEMEAKQNLERHISTLNIQ---LSDSKKKLQDFASTVEALE 300
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ ++ NL++ KA K + +R+ + + + V V + V + +
Sbjct: 301 EGKKRFQKEIENLTQQYEEKAAAYDK-LEKTKNRLQQELDDLV-VDLDNQRQLVSNLEKK 358
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
D + N + + D +K S+ AR +E + K E+
Sbjct: 359 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL------ARALEEALEAKEELE 412
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
R K L+ ++ +L S D K +L+K+ + Q+ E++T +E++ +LQ T D
Sbjct: 413 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 472
Query: 385 VAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ +Q+L G+ E +++ EQ +R +++Q E +T + + +++K K+E
Sbjct: 473 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 532
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+L + D K A ++ +++Q ++K L + + +I A K E + K
Sbjct: 533 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 592
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
++ L +++ + + +R + + +++ EL R+ E ++ ++
Sbjct: 593 SLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 651
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+ EE+Q N+ + D + K +Q+ +LA + +Q++ + ++ +R+
Sbjct: 652 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQQLERQ 702
Score = 81.8 bits (193), Expect = 7e-15
Identities = 73/359 (20%), Positives = 169/359 (47%), Gaps = 24/359 (6%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E+L ++ E + K+ + + K+ L+ + +L L V + +++ KK Q+ E
Sbjct: 114 VEELTEQL-EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 172
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+Q+ + +R D+ Q ++S+TG + E G + + S+ Q +++Q
Sbjct: 173 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 232
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ E T +N+S+ ++E+E + DE + + + + +L + + L +
Sbjct: 233 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 292
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ +E KK + E++N++ + EE +A A ++ ++L+ + D+ ++LD ++
Sbjct: 293 ASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKLEKTKNRLQQELDDLVVDLDNQR-- 349
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
+ + L KK+R+ +++ ++KNIS S Y + E +++
Sbjct: 350 --QLVSNLEKKQRKFDQLL----AEEKNIS-------------SKYADERDRAEAEAREK 390
Query: 605 VTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES-RALSSE 662
T+ R LE A + + E +++A+ V++ G V+ +++S RAL ++
Sbjct: 391 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 449
Score = 64.9 bits (151), Expect = 9e-10
Identities = 91/422 (21%), Positives = 175/422 (41%), Gaps = 27/422 (6%)
Query: 213 DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSY 272
D T + + AK E + T S V+ V + +L +
Sbjct: 69 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 128
Query: 273 LNQLNELKETV-KQFDDLS--VYILNDSSKQTSIEIEQLNARVVEAETKL------KSEV 323
N L++ K+T+ K+ DL+ + +L + ++ + ++L A+V E ++K ++E+
Sbjct: 129 AN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 187
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQ---LQVTL 380
KLQ ++ + L+ A I L K + S QL + Q E RQ + L
Sbjct: 188 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 247
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
Q + +Q E E + N E+ + ++ Q +S+ ++ + L K
Sbjct: 248 RQLEEERNSLQDQLDEEMEAKQNLERHIS---TLNIQLSDSKKKLQDFASTVEALEEGKK 304
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE- 499
+ ++E+ + Y+E ++ R+Q EL V L +++ + +E ++ +
Sbjct: 305 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 364
Query: 500 --IEVKNISVRL--EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
E KNIS + E A A K + AR + LE EE R T K+L+
Sbjct: 365 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELER---TNKMLKA- 420
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
++++++ ++ KN+ L+ S ++ K QL E E Q + R + +
Sbjct: 421 --EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 478
Query: 616 EA 617
+A
Sbjct: 479 QA 480
Score = 64.9 bits (151), Expect = 9e-10
Identities = 73/359 (20%), Positives = 151/359 (42%), Gaps = 12/359 (3%)
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-ARVVEAETKLKSEVTRIKKKLQIQI 334
+ EL E ++QF + D +KQT +E E + A + + K EV KKKL+ Q+
Sbjct: 114 VEELTEQLEQFKRAKANL--DKNKQT-LEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 170
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ-RQLQVTLDQYGVAQRRIQSL 393
EL+ + +L + K ++ + +E + + +++ D ++ + +
Sbjct: 171 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 230
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
EE R + ++ R +E++ Q +++E NL + + +L+
Sbjct: 231 ELLQEETRQKLNVSTKL-RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 289
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+ + +E +R Q E+++ + E+ K+E K L+ E+ ++ V L+
Sbjct: 290 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 349
Query: 514 --ANAIVGGKRIISKLEARIKDMELEL-DEEKRRHAETIKILRKK---ERQLKEVIIQCE 567
+ + +R +L A K++ + DE R AE + K R L+E + E
Sbjct: 350 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 409
Query: 568 EDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
E ++ +L+ +E + + E E + T++ + +LE ED E
Sbjct: 410 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE 468
Score = 64.5 bits (150), Expect = 1e-09
Identities = 72/322 (22%), Positives = 141/322 (43%), Gaps = 24/322 (7%)
Query: 308 LNARVVEAETKLKSEVTRIKK--KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
L A + + ++ + +KK +L+ I++L+ LD +K + +L +
Sbjct: 1 LQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 60
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLT----GEVEEIRGNYEQALRVKRSVEQQYEES 421
+T E++ L T Q + +R Q +T EE R + Q +++ Q EE
Sbjct: 61 KT---ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 117
Query: 422 QTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
++ + NL +K +E+E A +A ELR+ + Q V+ + K +
Sbjct: 118 TEQLEQFKRAKANLDKNKQTLEKENADLAG-------ELRVLGQAKQEVEHKKKKLEAQV 170
Query: 482 HEEQERIVKIEAVK-------KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
E Q + E + L+ EV++++ L E E AI K + S L ++++D
Sbjct: 171 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS-LSSQLQDT 229
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
+ L EE R+ LR+ E + + Q +E+ + L+ + + ++S K++L
Sbjct: 230 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 289
Query: 595 AEQEGMSQQSVTRVRRFQRELE 616
+ + +RFQ+E+E
Sbjct: 290 QDFASTVEALEEGKKRFQKEIE 311
Score = 50.8 bits (116), Expect = 2e-05
Identities = 58/287 (20%), Positives = 122/287 (42%), Gaps = 8/287 (2%)
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
R +E + E+ K+ + + LE L + ++ K+ L+ E+
Sbjct: 568 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 627
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELT 429
D+ + RI L E+EE +GN E + RV+++ +Q + S E +
Sbjct: 628 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERS 687
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
N SS+ ++E++ + + E+ ++ +++ L+ + L E+ E+
Sbjct: 688 TAQKN-ESSRQQLERQNKELRSKLHEMEGAVK---SKFKSTIAALEAKIAQLEEQVEQEA 743
Query: 490 KI-EAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELELDEEKRRHA 546
+ +A KSL+ + K + L +VE + K K AR+K ++ +L+E +
Sbjct: 744 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 803
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
RK +R+L E E + ++ L+ L + ++ + R+
Sbjct: 804 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRR 850
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 131 bits (316), Expect = 9e-30
Identities = 74/309 (23%), Positives = 156/309 (50%), Gaps = 1/309 (0%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ KQ ++ ++ A + E E K +S +KKL++ + +LE +D ANK + K +
Sbjct: 1004 EKKKQLVRQVREMEAEL-EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQL 1062
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+K Q+ + D+ + + L Q +++++S+ E+ +++ A R KR +
Sbjct: 1063 RKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQ 1122
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q+ +E + + K ++E +A + + +E + ++R ++ ++
Sbjct: 1123 QERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 1182
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
L+ E+ K E ++ LE + K + V+L+E+E K I+ LEA+I +E
Sbjct: 1183 QINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLE 1242
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
+LD E + K +R+ E++LK+V++Q +++++N +D +K S ++ KRQL
Sbjct: 1243 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1302
Query: 596 EQEGMSQQS 604
E E +Q++
Sbjct: 1303 EAEEEAQRA 1311
Score = 91.1 bits (216), Expect = 1e-17
Identities = 63/333 (18%), Positives = 164/333 (49%), Gaps = 5/333 (1%)
Query: 310 ARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
AR +E + K+E+ R+ K+ + ++ +L S D K+ +L+K+ + Q+ E++T
Sbjct: 904 ARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQL 963
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E++ +LQ T D + +Q++ + E +++G EQ+ K+ + +Q E + + +
Sbjct: 964 EELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDE 1023
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+++ K+E +L + A D K A ++ +++Q ++K + L + +
Sbjct: 1024 RKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASR 1083
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
+I A K E ++K++ + +++ + +R + + ++ E+ + A
Sbjct: 1084 EEILAQAKENEKKLKSMEAEMIQLQ-EELAAAERAKRQAQQERDELADEIANSSGKGALA 1142
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
++ R+ E ++ ++ + EE+Q N L+ D L+K + ++ L + +Q++
Sbjct: 1143 LEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENAR 1202
Query: 609 RRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
++ +R+ + + + E +++K++ +T
Sbjct: 1203 QQLERQNKELKVKLQEMEGT---VKSKYKASIT 1232
Score = 56.4 bits (130), Expect = 3e-07
Identities = 68/350 (19%), Positives = 174/350 (49%), Gaps = 26/350 (7%)
Query: 302 SIEIEQLNARVVEAETKLKSEV-TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSL 360
++E++ R+ +++ ++ V ++++ ++IT++ + + + +K K+
Sbjct: 610 ALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYL-ARKAFAKRQQ 668
Query: 361 QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL---TGEVEEIRGNYEQALRVKRSVEQQ 417
QLT ++ L++ Q+ +++ L + + EE+ E+ ++V+ E+Q
Sbjct: 669 QLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVR---EKQ 725
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAI---VAADYDEITKELRIADERYQRVQTEL 474
++ R+ E+ + L + K +++++L + A+ +E+ L + + + +L
Sbjct: 726 LA-AENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDL 784
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE-ANAIVGGKRIISKLEARIKD 533
+ VE EE+ER ++A KK ++ ++ + +LEE E A + +++ + EA++K
Sbjct: 785 EARVE---EEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTT--EAKLKK 839
Query: 534 MELELDE---EKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+E ELD+ + ++ L KK+++ +++ + + + +D E +++
Sbjct: 840 LEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGERDRAEAEAREKETK 899
Query: 591 KRQLAE--QEGMSQQS-VTRV-RRFQRELE-AAEDRADVAESNLSLIRAK 635
LA +E M Q++ + R+ ++F+ E+E + DV +S L ++K
Sbjct: 900 ALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSK 949
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 128 bits (308), Expect = 8e-29
Identities = 99/426 (23%), Positives = 200/426 (46%), Gaps = 10/426 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 1624
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 1625 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 1685 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 1743
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1803
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 1804 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1863
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 1864 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1923
Query: 632 IRAKHR 637
+++K R
Sbjct: 1924 LKSKLR 1929
Score = 93.9 bits (223), Expect = 2e-18
Identities = 89/471 (18%), Positives = 209/471 (44%), Gaps = 15/471 (3%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+++++E+E + + + L E+ K + R S I L +S++ +Q+ +
Sbjct: 1337 KLRQLEEERNSLQDQ--LDEEMEAKQNLERHISTLNIQ---LSDSKKKLQDFASTVEALE 1391
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ ++ NL++ KA K + +R+ + + + V V + V + +
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDK-LEKTKNRLQQELDDLV-VDLDNQRQLVSNLEKK 1449
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
D + N + + D +K S+ AR +E + K E+
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL------ARALEEALEAKEELE 1503
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
R K L+ ++ +L S D K +L+K+ + Q+ E++T +E++ +LQ T D
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1563
Query: 385 VAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ +Q+L G+ E +++ EQ +R +++Q E +T + + +++K K+E
Sbjct: 1564 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+L + D K A ++ +++Q ++K L + + +I A K E + K
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
++ L +++ + + +R + + +++ EL R+ E ++ ++
Sbjct: 1684 SLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 1742
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+ EE+Q N+ + D + K +Q+ +LA + +Q++ + ++ +R+
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793
Score = 81.8 bits (193), Expect = 7e-15
Identities = 73/359 (20%), Positives = 169/359 (47%), Gaps = 24/359 (6%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E+L ++ E + K+ + + K+ L+ + +L L V + +++ KK Q+ E
Sbjct: 1205 VEELTEQL-EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 1263
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+Q+ + +R D+ Q ++S+TG + E G + + S+ Q +++Q
Sbjct: 1264 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1323
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ E T +N+S+ ++E+E + DE + + + + +L + + L +
Sbjct: 1324 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1383
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ +E KK + E++N++ + EE +A A ++ ++L+ + D+ ++LD ++
Sbjct: 1384 ASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKLEKTKNRLQQELDDLVVDLDNQR-- 1440
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
+ + L KK+R+ +++ ++KNIS S Y + E +++
Sbjct: 1441 --QLVSNLEKKQRKFDQLL----AEEKNIS-------------SKYADERDRAEAEAREK 1481
Query: 605 VTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES-RALSSE 662
T+ R LE A + + E +++A+ V++ G V+ +++S RAL ++
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1540
Score = 79.0 bits (186), Expect = 5e-14
Identities = 58/267 (21%), Positives = 127/267 (47%), Gaps = 15/267 (5%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++Q D+ + R Q E++E+ + Q K +++Q + E +
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
V L++ K ++E+ L E+ L ++R Q++Q E K + + + +E++ + E
Sbjct: 911 VRLAAKKQELEEIL-------HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIV--GGKRIISK----LEARIKDMELELDEEKRRHA 546
A ++ L++E +++++E +V +SK LE RI D+ L EE+ +
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
K+ K E + E+ ++ ++++K+ L+ K S + Q+A+ + +
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
Query: 607 RVRRFQRELEAAEDRAD--VAESNLSL 631
++ + + EL+AA R D +A+ N +L
Sbjct: 1084 QLAKKEEELQAALARLDDEIAQKNNAL 1110
Score = 72.5 bits (170), Expect = 4e-12
Identities = 87/353 (24%), Positives = 166/353 (47%), Gaps = 42/353 (11%)
Query: 317 TKLKS--EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
TK+K +VTR ++++Q + EL+ + + K +L++ +K S QLTE + +Q
Sbjct: 839 TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHS-QLTE---EKNLLQE 894
Query: 375 QLQVTLDQYGVAQR---RIQSLTGEVEEI-------------RGNYEQALRVKRS----- 413
QLQ + Y A+ R+ + E+EEI RG QA R K +
Sbjct: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
+E+Q EE + +L + V + K+E E+ ++ ++++KE ++ +ER + T
Sbjct: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT- 1013
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
+L EE+E+ + +K E + + VRL++ E + +++ KLE D
Sbjct: 1014 ------NLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQELEKLKRKLEGDASD 1066
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEED--QKNISLLQDSLEKTSQKVSIYK 591
++ + + + AE L KKE +L+ + + +++ QKN +L + + +S +
Sbjct: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL--KKIRELEGHISDLQ 1124
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAE-DRADVAESNLSL--IRAKHRTFVT 641
L + ++ + R ELEA + + D +S + +RAK VT
Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1177
Score = 71.3 bits (167), Expect = 1e-11
Identities = 106/489 (21%), Positives = 211/489 (43%), Gaps = 42/489 (8%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q +R + ++ LDL E+++ RQK + + + I + E + QN ++ K
Sbjct: 942 QAERKKMAQQMLDL-EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK- 999
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITET-VRVRETSPTTCVVR 260
R L+ ++L+ N LA+ ++K + ++ I+E VR+++ +
Sbjct: 1000 ----ERKLLEERISDLTTN-LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS----- 1049
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
EL + ++ E Q DL I + Q + + E+L A + + ++
Sbjct: 1050 -RQELEKLKRKLEGDASDFHE---QIADLQAQIA-ELKMQLAKKEEELQAALARLDDEIA 1104
Query: 321 SEVTRIKK--KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ +KK +L+ I++L+ LD +K + +L ++T E++ L
Sbjct: 1105 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT---ELEDTLDS 1161
Query: 379 TLDQYGVAQRRIQSLT----GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
T Q + +R Q +T EE R + Q +++ Q EE ++ + N
Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L +K +E+E A +A ELR+ + Q V+ + K + E Q + E
Sbjct: 1222 LDKNKQTLEKENADLAG-------ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
Query: 495 K-------KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
+ L+ EV++++ L E E AI K + S L ++++D + L EE R+
Sbjct: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS-LSSQLQDTQELLQEETRQKLN 1333
Query: 548 TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
LR+ E + + Q +E+ + L+ + + ++S K++L + +
Sbjct: 1334 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG 1393
Query: 608 VRRFQRELE 616
+RFQ+E+E
Sbjct: 1394 KKRFQKEIE 1402
Score = 70.9 bits (166), Expect = 1e-11
Identities = 83/418 (19%), Positives = 172/418 (41%), Gaps = 12/418 (2%)
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTE--SITETVRVRETSPTTCVVRI 261
Q D +K KA E K + S++TE ++ + ET +
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK--QTSIEIEQLNARVVEAETKL 319
L A L+E++ +++ +D + + K Q +++E+ A KL
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+ E K + +I +LE + V + N L K K +++++ T+ E + + +
Sbjct: 970 QLE----KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ I L +++ + ++ ++KR +E + ++ +L L
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
AK E+EL A D+ + A ++ + ++ + E L E+ K E K+ L
Sbjct: 1086 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
E++ + LE+ ++ + + +K E + ++ LDEE R H ++ +R+K Q
Sbjct: 1146 EELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
E + E + + +L+K Q + LA + + Q+ V +++LEA
Sbjct: 1205 VE---ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1259
Score = 67.7 bits (158), Expect = 1e-10
Identities = 109/500 (21%), Positives = 208/500 (41%), Gaps = 37/500 (7%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKA-AMYRGKSAKAIAQTLLEE--SRRNVQNE----- 196
+MQ +KE +L L E+ QK A+ + + + L E+ S R +N+
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 197 RMYKPDFQASRTLVNR--DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSP 254
R + +A +T + D T + + AK E + T S V+
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETV-KQFDDLS--VYILNDSSKQTSIEIEQLNAR 311
V + +L + N L++ K+T+ K+ DL+ + +L + ++ + ++L A+
Sbjct: 1202 AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
Query: 312 VVEAETKL------KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
V E ++K ++E+ KLQ ++ + L+ A I L K + S QL +
Sbjct: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
Query: 366 QTHYDEVQRQ---LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
Q E RQ + L Q + +Q E E + N E+ + ++ Q +S+
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS---TLNIQLSDSK 1377
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ + L K + ++E+ + Y+E ++ R+Q EL V L
Sbjct: 1378 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
Query: 483 EEQERIVKIEAVKKSLE---IEVKNISVRL--EEVEANAIVGGKRIISKLEARIKDMELE 537
+++ + +E ++ + E KNIS + E A A K + AR + LE
Sbjct: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1497
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
EE R T K+L+ ++++++ ++ KN+ L+ S ++ K QL E
Sbjct: 1498 AKEELER---TNKMLKA---EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551
Query: 598 EGMSQQSVTRVRRFQRELEA 617
E Q + R + ++A
Sbjct: 1552 EDELQATEDAKLRLEVNMQA 1571
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 128 bits (308), Expect = 8e-29
Identities = 99/426 (23%), Positives = 200/426 (46%), Gaps = 10/426 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 1624
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 1625 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 1685 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 1743
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1803
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 1804 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1863
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 1864 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1923
Query: 632 IRAKHR 637
+++K R
Sbjct: 1924 LKSKLR 1929
Score = 93.9 bits (223), Expect = 2e-18
Identities = 89/471 (18%), Positives = 209/471 (44%), Gaps = 15/471 (3%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+++++E+E + + + L E+ K + R S I L +S++ +Q+ +
Sbjct: 1337 KLRQLEEERNSLQDQ--LDEEMEAKQNLERHISTLNIQ---LSDSKKKLQDFASTVEALE 1391
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ ++ NL++ KA K + +R+ + + + V V + V + +
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDK-LEKTKNRLQQELDDLV-VDLDNQRQLVSNLEKK 1449
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
D + N + + D +K S+ AR +E + K E+
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL------ARALEEALEAKEELE 1503
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
R K L+ ++ +L S D K +L+K+ + Q+ E++T +E++ +LQ T D
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1563
Query: 385 VAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ +Q+L G+ E +++ EQ +R +++Q E +T + + +++K K+E
Sbjct: 1564 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+L + D K A ++ +++Q ++K L + + +I A K E + K
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
++ L +++ + + +R + + +++ EL R+ E ++ ++
Sbjct: 1684 SLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 1742
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+ EE+Q N+ + D + K +Q+ +LA + +Q++ + ++ +R+
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793
Score = 81.8 bits (193), Expect = 7e-15
Identities = 73/359 (20%), Positives = 169/359 (47%), Gaps = 24/359 (6%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E+L ++ E + K+ + + K+ L+ + +L L V + +++ KK Q+ E
Sbjct: 1205 VEELTEQL-EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 1263
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+Q+ + +R D+ Q ++S+TG + E G + + S+ Q +++Q
Sbjct: 1264 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1323
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ E T +N+S+ ++E+E + DE + + + + +L + + L +
Sbjct: 1324 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1383
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ +E KK + E++N++ + EE +A A ++ ++L+ + D+ ++LD ++
Sbjct: 1384 ASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKLEKTKNRLQQELDDLVVDLDNQR-- 1440
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
+ + L KK+R+ +++ ++KNIS S Y + E +++
Sbjct: 1441 --QLVSNLEKKQRKFDQLL----AEEKNIS-------------SKYADERDRAEAEAREK 1481
Query: 605 VTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES-RALSSE 662
T+ R LE A + + E +++A+ V++ G V+ +++S RAL ++
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1540
Score = 79.0 bits (186), Expect = 5e-14
Identities = 58/267 (21%), Positives = 127/267 (47%), Gaps = 15/267 (5%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++Q D+ + R Q E++E+ + Q K +++Q + E +
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
V L++ K ++E+ L E+ L ++R Q++Q E K + + + +E++ + E
Sbjct: 911 VRLAAKKQELEEIL-------HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIV--GGKRIISK----LEARIKDMELELDEEKRRHA 546
A ++ L++E +++++E +V +SK LE RI D+ L EE+ +
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
K+ K E + E+ ++ ++++K+ L+ K S + Q+A+ + +
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
Query: 607 RVRRFQRELEAAEDRAD--VAESNLSL 631
++ + + EL+AA R D +A+ N +L
Sbjct: 1084 QLAKKEEELQAALARLDDEIAQKNNAL 1110
Score = 72.5 bits (170), Expect = 4e-12
Identities = 87/353 (24%), Positives = 166/353 (47%), Gaps = 42/353 (11%)
Query: 317 TKLKS--EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
TK+K +VTR ++++Q + EL+ + + K +L++ +K S QLTE + +Q
Sbjct: 839 TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHS-QLTE---EKNLLQE 894
Query: 375 QLQVTLDQYGVAQR---RIQSLTGEVEEI-------------RGNYEQALRVKRS----- 413
QLQ + Y A+ R+ + E+EEI RG QA R K +
Sbjct: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
+E+Q EE + +L + V + K+E E+ ++ ++++KE ++ +ER + T
Sbjct: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT- 1013
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
+L EE+E+ + +K E + + VRL++ E + +++ KLE D
Sbjct: 1014 ------NLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQELEKLKRKLEGDASD 1066
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEED--QKNISLLQDSLEKTSQKVSIYK 591
++ + + + AE L KKE +L+ + + +++ QKN +L + + +S +
Sbjct: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL--KKIRELEGHISDLQ 1124
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAE-DRADVAESNLSL--IRAKHRTFVT 641
L + ++ + R ELEA + + D +S + +RAK VT
Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1177
Score = 71.3 bits (167), Expect = 1e-11
Identities = 106/489 (21%), Positives = 211/489 (43%), Gaps = 42/489 (8%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q +R + ++ LDL E+++ RQK + + + I + E + QN ++ K
Sbjct: 942 QAERKKMAQQMLDL-EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK- 999
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITET-VRVRETSPTTCVVR 260
R L+ ++L+ N LA+ ++K + ++ I+E VR+++ +
Sbjct: 1000 ----ERKLLEERISDLTTN-LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS----- 1049
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
EL + ++ E Q DL I + Q + + E+L A + + ++
Sbjct: 1050 -RQELEKLKRKLEGDASDFHE---QIADLQAQIA-ELKMQLAKKEEELQAALARLDDEIA 1104
Query: 321 SEVTRIKK--KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ +KK +L+ I++L+ LD +K + +L ++T E++ L
Sbjct: 1105 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT---ELEDTLDS 1161
Query: 379 TLDQYGVAQRRIQSLT----GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
T Q + +R Q +T EE R + Q +++ Q EE ++ + N
Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L +K +E+E A +A ELR+ + Q V+ + K + E Q + E
Sbjct: 1222 LDKNKQTLEKENADLAG-------ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
Query: 495 K-------KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
+ L+ EV++++ L E E AI K + S L ++++D + L EE R+
Sbjct: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS-LSSQLQDTQELLQEETRQKLN 1333
Query: 548 TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
LR+ E + + Q +E+ + L+ + + ++S K++L + +
Sbjct: 1334 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG 1393
Query: 608 VRRFQRELE 616
+RFQ+E+E
Sbjct: 1394 KKRFQKEIE 1402
Score = 70.9 bits (166), Expect = 1e-11
Identities = 83/418 (19%), Positives = 172/418 (41%), Gaps = 12/418 (2%)
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTE--SITETVRVRETSPTTCVVRI 261
Q D +K KA E K + S++TE ++ + ET +
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK--QTSIEIEQLNARVVEAETKL 319
L A L+E++ +++ +D + + K Q +++E+ A KL
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+ E K + +I +LE + V + N L K K +++++ T+ E + + +
Sbjct: 970 QLE----KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ I L +++ + ++ ++KR +E + ++ +L L
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
AK E+EL A D+ + A ++ + ++ + E L E+ K E K+ L
Sbjct: 1086 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
E++ + LE+ ++ + + +K E + ++ LDEE R H ++ +R+K Q
Sbjct: 1146 EELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
E + E + + +L+K Q + LA + + Q+ V +++LEA
Sbjct: 1205 VE---ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1259
Score = 67.7 bits (158), Expect = 1e-10
Identities = 109/500 (21%), Positives = 208/500 (41%), Gaps = 37/500 (7%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKA-AMYRGKSAKAIAQTLLEE--SRRNVQNE----- 196
+MQ +KE +L L E+ QK A+ + + + L E+ S R +N+
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 197 RMYKPDFQASRTLVNR--DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSP 254
R + +A +T + D T + + AK E + T S V+
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETV-KQFDDLS--VYILNDSSKQTSIEIEQLNAR 311
V + +L + N L++ K+T+ K+ DL+ + +L + ++ + ++L A+
Sbjct: 1202 AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
Query: 312 VVEAETKL------KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
V E ++K ++E+ KLQ ++ + L+ A I L K + S QL +
Sbjct: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
Query: 366 QTHYDEVQRQ---LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
Q E RQ + L Q + +Q E E + N E+ + ++ Q +S+
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS---TLNIQLSDSK 1377
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ + L K + ++E+ + Y+E ++ R+Q EL V L
Sbjct: 1378 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
Query: 483 EEQERIVKIEAVKKSLE---IEVKNISVRL--EEVEANAIVGGKRIISKLEARIKDMELE 537
+++ + +E ++ + E KNIS + E A A K + AR + LE
Sbjct: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1497
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
EE R T K+L+ ++++++ ++ KN+ L+ S ++ K QL E
Sbjct: 1498 AKEELER---TNKMLKA---EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551
Query: 598 EGMSQQSVTRVRRFQRELEA 617
E Q + R + ++A
Sbjct: 1552 EDELQATEDAKLRLEVNMQA 1571
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 128 bits (308), Expect = 8e-29
Identities = 99/426 (23%), Positives = 200/426 (46%), Gaps = 10/426 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1572
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 1631
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 1632 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1691
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 1692 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 1750
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1810
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 1811 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 1870
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 1871 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1930
Query: 632 IRAKHR 637
+++K R
Sbjct: 1931 LKSKLR 1936
Score = 93.9 bits (223), Expect = 2e-18
Identities = 89/471 (18%), Positives = 209/471 (44%), Gaps = 15/471 (3%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+++++E+E + + + L E+ K + R S I L +S++ +Q+ +
Sbjct: 1344 KLRQLEEERNSLQDQ--LDEEMEAKQNLERHISTLNIQ---LSDSKKKLQDFASTVEALE 1398
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ ++ NL++ KA K + +R+ + + + V V + V + +
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDK-LEKTKNRLQQELDDLV-VDLDNQRQLVSNLEKK 1456
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
D + N + + D +K S+ AR +E + K E+
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL------ARALEEALEAKEELE 1510
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
R K L+ ++ +L S D K +L+K+ + Q+ E++T +E++ +LQ T D
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1570
Query: 385 VAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ +Q+L G+ E +++ EQ +R +++Q E +T + + +++K K+E
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+L + D K A ++ +++Q ++K L + + +I A K E + K
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1690
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
++ L +++ + + +R + + +++ EL R+ E ++ ++
Sbjct: 1691 SLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 1749
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+ EE+Q N+ + D + K +Q+ +LA + +Q++ + ++ +R+
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800
Score = 81.8 bits (193), Expect = 7e-15
Identities = 73/359 (20%), Positives = 169/359 (47%), Gaps = 24/359 (6%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E+L ++ E + K+ + + K+ L+ + +L L V + +++ KK Q+ E
Sbjct: 1212 VEELTEQL-EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 1270
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+Q+ + +R D+ Q ++S+TG + E G + + S+ Q +++Q
Sbjct: 1271 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 1330
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ E T +N+S+ ++E+E + DE + + + + +L + + L +
Sbjct: 1331 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1390
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ +E KK + E++N++ + EE +A A ++ ++L+ + D+ ++LD ++
Sbjct: 1391 ASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKLEKTKNRLQQELDDLVVDLDNQR-- 1447
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
+ + L KK+R+ +++ ++KNIS S Y + E +++
Sbjct: 1448 --QLVSNLEKKQRKFDQLL----AEEKNIS-------------SKYADERDRAEAEAREK 1488
Query: 605 VTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES-RALSSE 662
T+ R LE A + + E +++A+ V++ G V+ +++S RAL ++
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1547
Score = 79.0 bits (186), Expect = 5e-14
Identities = 58/267 (21%), Positives = 127/267 (47%), Gaps = 15/267 (5%)
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ ++Q D+ + R Q E++E+ + Q K +++Q + E +
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
V L++ K ++E+ L E+ L ++R Q++Q E K + + + +E++ + E
Sbjct: 918 VRLAAKKQELEEIL-------HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIV--GGKRIISK----LEARIKDMELELDEEKRRHA 546
A ++ L++E +++++E +V +SK LE RI D+ L EE+ +
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
K+ K E + E+ ++ ++++K+ L+ K S + Q+A+ + +
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090
Query: 607 RVRRFQRELEAAEDRAD--VAESNLSL 631
++ + + EL+AA R D +A+ N +L
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNAL 1117
Score = 72.5 bits (170), Expect = 4e-12
Identities = 87/353 (24%), Positives = 166/353 (47%), Gaps = 42/353 (11%)
Query: 317 TKLKS--EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
TK+K +VTR ++++Q + EL+ + + K +L++ +K S QLTE + +Q
Sbjct: 846 TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHS-QLTE---EKNLLQE 901
Query: 375 QLQVTLDQYGVAQR---RIQSLTGEVEEI-------------RGNYEQALRVKRS----- 413
QLQ + Y A+ R+ + E+EEI RG QA R K +
Sbjct: 902 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 961
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
+E+Q EE + +L + V + K+E E+ ++ ++++KE ++ +ER + T
Sbjct: 962 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT- 1020
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
+L EE+E+ + +K E + + VRL++ E + +++ KLE D
Sbjct: 1021 ------NLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQELEKLKRKLEGDASD 1073
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEED--QKNISLLQDSLEKTSQKVSIYK 591
++ + + + AE L KKE +L+ + + +++ QKN +L + + +S +
Sbjct: 1074 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL--KKIRELEGHISDLQ 1131
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAE-DRADVAESNLSL--IRAKHRTFVT 641
L + ++ + R ELEA + + D +S + +RAK VT
Sbjct: 1132 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1184
Score = 71.3 bits (167), Expect = 1e-11
Identities = 106/489 (21%), Positives = 211/489 (43%), Gaps = 42/489 (8%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q +R + ++ LDL E+++ RQK + + + I + E + QN ++ K
Sbjct: 949 QAERKKMAQQMLDL-EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK- 1006
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITET-VRVRETSPTTCVVR 260
R L+ ++L+ N LA+ ++K + ++ I+E VR+++ +
Sbjct: 1007 ----ERKLLEERISDLTTN-LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS----- 1056
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
EL + ++ E Q DL I + Q + + E+L A + + ++
Sbjct: 1057 -RQELEKLKRKLEGDASDFHE---QIADLQAQIA-ELKMQLAKKEEELQAALARLDDEIA 1111
Query: 321 SEVTRIKK--KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ +KK +L+ I++L+ LD +K + +L ++T E++ L
Sbjct: 1112 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT---ELEDTLDS 1168
Query: 379 TLDQYGVAQRRIQSLT----GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
T Q + +R Q +T EE R + Q +++ Q EE ++ + N
Sbjct: 1169 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1228
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L +K +E+E A +A ELR+ + Q V+ + K + E Q + E
Sbjct: 1229 LDKNKQTLEKENADLAG-------ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1281
Query: 495 K-------KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
+ L+ EV++++ L E E AI K + S L ++++D + L EE R+
Sbjct: 1282 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS-LSSQLQDTQELLQEETRQKLN 1340
Query: 548 TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
LR+ E + + Q +E+ + L+ + + ++S K++L + +
Sbjct: 1341 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG 1400
Query: 608 VRRFQRELE 616
+RFQ+E+E
Sbjct: 1401 KKRFQKEIE 1409
Score = 70.9 bits (166), Expect = 1e-11
Identities = 83/418 (19%), Positives = 172/418 (41%), Gaps = 12/418 (2%)
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTE--SITETVRVRETSPTTCVVRI 261
Q D +K KA E K + S++TE ++ + ET +
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK--QTSIEIEQLNARVVEAETKL 319
L A L+E++ +++ +D + + K Q +++E+ A KL
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+ E K + +I +LE + V + N L K K +++++ T+ E + + +
Sbjct: 977 QLE----KVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ I L +++ + ++ ++KR +E + ++ +L L
Sbjct: 1033 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1092
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
AK E+EL A D+ + A ++ + ++ + E L E+ K E K+ L
Sbjct: 1093 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1152
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
E++ + LE+ ++ + + +K E + ++ LDEE R H ++ +R+K Q
Sbjct: 1153 EELEALKTELEDT-LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA 1211
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
E + E + + +L+K Q + LA + + Q+ V +++LEA
Sbjct: 1212 VE---ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1266
Score = 67.7 bits (158), Expect = 1e-10
Identities = 109/500 (21%), Positives = 208/500 (41%), Gaps = 37/500 (7%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKA-AMYRGKSAKAIAQTLLEE--SRRNVQNE----- 196
+MQ +KE +L L E+ QK A+ + + + L E+ S R +N+
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 197 RMYKPDFQASRTLVNR--DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSP 254
R + +A +T + D T + + AK E + T S V+
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETV-KQFDDLS--VYILNDSSKQTSIEIEQLNAR 311
V + +L + N L++ K+T+ K+ DL+ + +L + ++ + ++L A+
Sbjct: 1209 AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1267
Query: 312 VVEAETKL------KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
V E ++K ++E+ KLQ ++ + L+ A I L K + S QL +
Sbjct: 1268 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1327
Query: 366 QTHYDEVQRQ---LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
Q E RQ + L Q + +Q E E + N E+ + ++ Q +S+
Sbjct: 1328 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS---TLNIQLSDSK 1384
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ + L K + ++E+ + Y+E ++ R+Q EL V L
Sbjct: 1385 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1444
Query: 483 EEQERIVKIEAVKKSLE---IEVKNISVRL--EEVEANAIVGGKRIISKLEARIKDMELE 537
+++ + +E ++ + E KNIS + E A A K + AR + LE
Sbjct: 1445 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1504
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
EE R T K+L+ ++++++ ++ KN+ L+ S ++ K QL E
Sbjct: 1505 AKEELER---TNKMLKA---EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558
Query: 598 EGMSQQSVTRVRRFQRELEA 617
E Q + R + ++A
Sbjct: 1559 EDELQATEDAKLRLEVNMQA 1578
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 128 bits (308), Expect = 8e-29
Identities = 99/426 (23%), Positives = 200/426 (46%), Gaps = 10/426 (2%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 156 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 215
Query: 276 LNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV--TRIKKKLQI 332
++ QF+ DL + K+ ++ QL+ E E + K KKKL+
Sbjct: 216 EVNMQALKGQFERDLQARDEQNEEKRRQLQ-RQLHEYETELEDERKQRALAAAAKKKLEG 274
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+ +LEL D A K + K ++K Q+ + Q ++ + +++ +S
Sbjct: 275 DLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 334
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
L ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A +
Sbjct: 335 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEE 393
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
+ +E + +R ++ + + L E+ K E+ ++ LE + K + +L E
Sbjct: 394 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 453
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+++K
Sbjct: 454 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 513
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ EK + +V KRQL E E SQ+ R+ QREL+ A + + ++
Sbjct: 514 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 573
Query: 632 IRAKHR 637
+++K R
Sbjct: 574 LKSKLR 579
Score = 91.9 bits (218), Expect = 7e-18
Identities = 64/306 (20%), Positives = 147/306 (48%), Gaps = 2/306 (0%)
Query: 310 ARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
AR +E + K E+ R K L+ ++ +L S D K +L+K+ + Q+ E++T
Sbjct: 139 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 198
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E++ +LQ T D + +Q+L G+ E +++ EQ +R +++Q E +T + +
Sbjct: 199 EELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 258
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+++K K+E +L + D K A + +++Q ++K L + +
Sbjct: 259 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASR 318
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
+I A K E + K++ L +++ + + +R + + +++ EL
Sbjct: 319 DEIFATAKENEKKAKSLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNAL 377
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
R+ E ++ ++ + EE+Q N+ + D + K +Q+ +LA + +Q++ +
Sbjct: 378 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 437
Query: 609 RRFQRE 614
++ +R+
Sbjct: 438 QQLERQ 443
Score = 75.8 bits (178), Expect = 5e-13
Identities = 79/376 (21%), Positives = 172/376 (45%), Gaps = 14/376 (3%)
Query: 260 RINTELPAIDN--SYLNQLN-ELKETVKQFDDLS--VYILNDSSKQTSIEIEQLNARVVE 314
++N E+ A N +++ LN +L ++ K+ D + V L + K+ EIE L + E
Sbjct: 1 QLNEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-E 59
Query: 315 AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
+ ++ + K +LQ ++ +L + LD + +L+K +K L E + +
Sbjct: 60 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 119
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+ + + + SL +EE E+ R + ++ + E+ + +++
Sbjct: 120 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 179
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE-QERIVKIEA 493
L SK +E ++ + +E+ EL+ ++ R++ ++ + Q R + E
Sbjct: 180 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 494 VKKSLEIEVKNISVRLE-EVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
++ L+ ++ LE E + A+ + KLE +KD+EL+ D + E IK +
Sbjct: 240 KRRQLQRQLHEYETELEDERKQRALAAAAK--KKLEGDLKDLELQADSAIKGREEAIKHV 297
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE-QEGMSQQSVTRVRRF 611
RK + Q+K+ + E+ + + + + ++ +K + L + QE ++ + R R+
Sbjct: 298 RKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLA--AAERARK- 354
Query: 612 QRELEAAEDRADVAES 627
Q +LE E ++A S
Sbjct: 355 QADLEKEELAEELASS 370
Score = 58.0 bits (134), Expect = 1e-07
Identities = 58/279 (20%), Positives = 121/279 (43%), Gaps = 17/279 (6%)
Query: 361 QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEE 420
QL E ++R + Q +++++Q VE + ++ + ++ QQYEE
Sbjct: 1 QLNEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE 60
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYD---EITKELRIADERYQRVQTELKHT 477
++L +K +++QEL + D D ++ L ++ ++ E K+
Sbjct: 61 KAAAYDKL-------EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNI 113
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE-VEANAIVGGKRIISKLEARIKDMEL 536
+E++R EA + E + +++ LEE +EA + +R L+A ++D+
Sbjct: 114 SSKYADERDR---AEAEAREKETKALSLARALEEALEAKEEL--ERTNKMLKAEMEDLVS 168
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL-A 595
D+ + E K R E Q++E+ Q EE + + +D+ + + K Q
Sbjct: 169 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 228
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRA 634
+ + +Q+ + R+ QR+L E + +L A
Sbjct: 229 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 267
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 126 bits (303), Expect = 3e-28
Identities = 100/429 (23%), Positives = 201/429 (46%), Gaps = 16/429 (3%)
Query: 220 NVLAKALMESKAMNSCD-SRVTESITETVRVRETSPT---TCVVRINTELPAIDNSYLNQ 275
N + KA ME + D + + ++ R ET T + + EL A +++ L
Sbjct: 620 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASEDAKLRL 679
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE------VTRIKKK 329
++ QF+ L +Q + QL ++ E ET+L+ E KKK
Sbjct: 680 EVNMQALKGQFER----DLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKKK 735
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
L+ + +LEL D A K + K ++K Q+ + Q ++ + +++
Sbjct: 736 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 795
Query: 390 IQSLTGEVEEIRGNYEQALRVKRSVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAI 448
+SL ++ +++ + A R ++ + + EE ++ + L+ N L K ++E +A
Sbjct: 796 AKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQ 854
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVR 508
+ + +E + +R ++ + + L E+ K E+ ++ LE + K + +
Sbjct: 855 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 914
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
L E+E K I+ LEA+I +E ++++E R K L++K+++LKE+++Q E+
Sbjct: 915 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 974
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESN 628
++K ++ EK + +V KRQL E E SQ+ R+ QREL+ A + +
Sbjct: 975 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1034
Query: 629 LSLIRAKHR 637
++ +++K R
Sbjct: 1035 VNALKSKLR 1043
Score = 91.9 bits (218), Expect = 7e-18
Identities = 88/471 (18%), Positives = 209/471 (44%), Gaps = 15/471 (3%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+++++E+E + + + L E+ K + R S I L +S++ +Q+ +
Sbjct: 451 KLRQLEEERNSLQDQ--LDEEMEAKQNLERHISTLNIQ---LSDSKKKLQDFASTVEALE 505
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ ++ NL++ KA K + +R+ + + + V V + V + +
Sbjct: 506 EGKKRFQKEIENLTQQYEEKAAAYDK-LEKTKNRLQQELDDLV-VDLDNQRQLVSNLEKK 563
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
D + N + + D +K S+ AR +E + K E+
Sbjct: 564 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL------ARALEEALEAKEELE 617
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
R K L+ ++ +L S D K +L+K+ + Q+ E++T +E++ +LQ + D
Sbjct: 618 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASEDAKL 677
Query: 385 VAQRRIQSLTGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
+ +Q+L G+ E +++ EQ +R +++Q E +T + + +++K K+E
Sbjct: 678 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKKKLE 737
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+L + D K A ++ +++Q ++K L + + +I A K E + K
Sbjct: 738 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 797
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
++ L +++ + + +R + + +++ EL R+ E ++ ++
Sbjct: 798 SLEADLMQLQED-LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE 856
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+ EE+Q N+ + D + K +Q+ +LA + +Q++ + ++ +R+
Sbjct: 857 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 907
Score = 81.8 bits (193), Expect = 7e-15
Identities = 73/359 (20%), Positives = 169/359 (47%), Gaps = 24/359 (6%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E+L ++ E + K+ + + K+ L+ + +L L V + +++ KK Q+ E
Sbjct: 319 VEELTEQL-EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQE 377
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+Q+ + +R D+ Q ++S+TG + E G + + S+ Q +++Q
Sbjct: 378 LQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL 437
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ E T +N+S+ ++E+E + DE + + + + +L + + L +
Sbjct: 438 LQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 497
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ +E KK + E++N++ + EE +A A ++ ++L+ + D+ ++LD ++
Sbjct: 498 ASTVEALEEGKKRFQKEIENLTQQYEE-KAAAYDKLEKTKNRLQQELDDLVVDLDNQR-- 554
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
+ + L KK+R+ +++ ++KNIS S Y + E +++
Sbjct: 555 --QLVSNLEKKQRKFDQLL----AEEKNIS-------------SKYADERDRAEAEAREK 595
Query: 605 VTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES-RALSSE 662
T+ R LE A + + E +++A+ V++ G V+ +++S RAL ++
Sbjct: 596 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 654
Score = 71.3 bits (167), Expect = 1e-11
Identities = 106/489 (21%), Positives = 211/489 (43%), Gaps = 42/489 (8%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q +R + ++ LDL E+++ RQK + + + I + E + QN ++ K
Sbjct: 56 QAERKKMAQQMLDL-EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSK- 113
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITET-VRVRETSPTTCVVR 260
R L+ ++L+ N LA+ ++K + ++ I+E VR+++ +
Sbjct: 114 ----ERKLLEERISDLTTN-LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS----- 163
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
EL + ++ E Q DL I + Q + + E+L A + + ++
Sbjct: 164 -RQELEKLKRKLEGDASDFHE---QIADLQAQIA-ELKMQLAKKEEELQAALARLDDEIA 218
Query: 321 SEVTRIKK--KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ +KK +L+ I++L+ LD +K + +L ++T E++ L
Sbjct: 219 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT---ELEDTLDS 275
Query: 379 TLDQYGVAQRRIQSLT----GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
T Q + +R Q +T EE R + Q +++ Q EE ++ + N
Sbjct: 276 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 335
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L +K +E+E A +A ELR+ + Q V+ + K + E Q + E
Sbjct: 336 LDKNKQTLEKENADLAG-------ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 388
Query: 495 K-------KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE 547
+ L+ EV++++ L E E AI K + S L ++++D + L EE R+
Sbjct: 389 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS-LSSQLQDTQELLQEETRQKLN 447
Query: 548 TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
LR+ E + + Q +E+ + L+ + + ++S K++L + +
Sbjct: 448 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG 507
Query: 608 VRRFQRELE 616
+RFQ+E+E
Sbjct: 508 KKRFQKEIE 516
Score = 70.5 bits (165), Expect = 2e-11
Identities = 74/361 (20%), Positives = 157/361 (43%), Gaps = 10/361 (2%)
Query: 306 EQLNARV---VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
EQL A EAE +++ + K++L+ + E+E L+ LQ KK + Q+
Sbjct: 8 EQLQAETELYAEAE-EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQM 66
Query: 363 TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
+++ +E + Q + A+ +I+ L E+ + + + ++ +E++ +
Sbjct: 67 LDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLT 126
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
T + E NL+ K K E ++ + + K + ++ ++++ + E +
Sbjct: 127 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 186
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
+ Q +I +++ E E++ RL++ A K+ I +LE I D++ +LD E+
Sbjct: 187 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKK-IRELEGHISDLQEDLDSER 245
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ K R +L+ + + E+ + + Q+ K Q+V++ K+ L E+ +
Sbjct: 246 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHE 305
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSE 662
V +R Q+ +A E+ + E RAK T+ L E R L
Sbjct: 306 AQVQEMR--QKHAQAVEELTEQLE---QFKRAKANLDKNKQTLEKENADLAGELRVLGQA 360
Query: 663 R 663
+
Sbjct: 361 K 361
Score = 69.3 bits (162), Expect = 4e-11
Identities = 67/329 (20%), Positives = 146/329 (44%), Gaps = 12/329 (3%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ-------ITELELSLDVANKTN 348
D +Q E +++ ++++ E +L+ E ++KLQ++ I +LE + V + N
Sbjct: 50 DRGQQLQAERKKMAQQMLDLEEQLEEEEAA-RQKLQLEKVTAEAKIKKLEDEILVMDDQN 108
Query: 349 IDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL 408
L K K +++++ T+ E + + + + I L +++ + ++
Sbjct: 109 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 168
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQ 468
++KR +E + ++ +L L AK E+EL A D+ + A ++ +
Sbjct: 169 KLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 228
Query: 469 RVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLE 528
++ + E L E+ K E K+ L E++ + LE+ ++ + + +K E
Sbjct: 229 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT-LDSTATQQELRAKRE 287
Query: 529 ARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
+ ++ LDEE R H ++ +R+K Q E + E + + +L+K Q +
Sbjct: 288 QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVE---ELTEQLEQFKRAKANLDKNKQTLE 344
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
LA + + Q+ V +++LEA
Sbjct: 345 KENADLAGELRVLGQAKQEVEHKKKKLEA 373
Score = 68.9 bits (161), Expect = 5e-11
Identities = 110/500 (22%), Positives = 208/500 (41%), Gaps = 37/500 (7%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKA-AMYRGKSAKAIAQTLLEE--SRRNVQNE----- 196
+MQ +KE +L L E+ QK A+ + + + L E+ S R +N+
Sbjct: 196 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 255
Query: 197 RMYKPDFQASRTLVNR--DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSP 254
R + +A +T + D T + + AK E + T S V+
Sbjct: 256 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 315
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETV-KQFDDLS--VYILNDSSKQTSIEIEQLNAR 311
V + +L + N L++ K+T+ K+ DL+ + +L + ++ + ++L A+
Sbjct: 316 AQAVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 374
Query: 312 VVEAETKL------KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
V E ++K ++E+ KLQ ++ + L+ A I L K + S QL +
Sbjct: 375 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 434
Query: 366 QTHYDEVQRQ---LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
Q E RQ + L Q + +Q E E + N E+ + ++ Q +S+
Sbjct: 435 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS---TLNIQLSDSK 491
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ + L K + ++E+ + Y+E ++ R+Q EL V L
Sbjct: 492 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 551
Query: 483 EEQERIVKIEAVKKSLE---IEVKNISVRL--EEVEANAIVGGKRIISKLEARIKDMELE 537
+++ + +E ++ + E KNIS + E A A K + AR + LE
Sbjct: 552 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 611
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
EE R T K+L+ ++++++ ++ KN+ L+ S ++ K QL E
Sbjct: 612 AKEELER---TNKMLKA---EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 665
Query: 598 EGMSQQSVTRVRRFQRELEA 617
E Q S R + ++A
Sbjct: 666 EDELQASEDAKLRLEVNMQA 685
Score = 65.3 bits (152), Expect = 7e-10
Identities = 50/226 (22%), Positives = 110/226 (48%), Gaps = 15/226 (6%)
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
+++Q + E + V L++ K ++E+ L E+ L ++R Q++Q E
Sbjct: 6 LQEQLQAETELYAEAEEMRVRLAAKKQELEEIL-------HEMEARLEEEEDRGQQLQAE 58
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV--GGKRIISK----L 527
K + + + +E++ + EA ++ L++E +++++E +V +SK L
Sbjct: 59 RKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 118
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
E RI D+ L EE+ + K+ K E + E+ ++ ++++K+ L+ K
Sbjct: 119 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 178
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD--VAESNLSL 631
S + Q+A+ + + ++ + + EL+AA R D +A+ N +L
Sbjct: 179 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL 224
Score = 64.1 bits (149), Expect = 2e-09
Identities = 67/300 (22%), Positives = 138/300 (46%), Gaps = 21/300 (7%)
Query: 352 QKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVK 411
+ +++Q TE+ +E++ +L + +++ E EE RG QA R K
Sbjct: 3 ENLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEE-EEDRGQQLQAERKK 61
Query: 412 RS-----VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADER 466
+ +E+Q EE + +L + V + K+E E+ ++ ++++KE ++ +ER
Sbjct: 62 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER 121
Query: 467 YQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISK 526
+ T +L EE+E+ + +K E + + VRL++ E + +++ K
Sbjct: 122 ISDLTT-------NLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQELEKLKRK 173
Query: 527 LEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED--QKNISLLQDSLEKTS 584
LE D ++ + + + AE L KKE +L+ + + +++ QKN +L + +
Sbjct: 174 LEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNAL--KKIRELE 231
Query: 585 QKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE-DRADVAESNLSL--IRAKHRTFVT 641
+S + L + ++ + R ELEA + + D +S + +RAK VT
Sbjct: 232 GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 291
>Z32858-1|CAA83687.1| 119|Homo sapiens fast 2a myosin heavy chain
(3' end) protein.
Length = 119
Score = 108 bits (259), Expect = 7e-23
Identities = 51/109 (46%), Positives = 77/109 (70%)
Query: 529 ARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
AR++++E E++ E++R+AE ++ LRK ER++KE+ Q EED+KNI LQD ++K KV
Sbjct: 1 ARVRELEGEVESEQKRNAEAVRGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVK 60
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
YKRQ E E S ++ + R+ Q ELE AE+RAD+AES ++ +R K R
Sbjct: 61 SYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 109
>S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 330
Score = 108 bits (259), Expect = 7e-23
Identities = 69/295 (23%), Positives = 145/295 (49%), Gaps = 2/295 (0%)
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K ++K Q+ + Q ++ + +++ +SL ++ +++ + A R ++
Sbjct: 3 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 62
Query: 413 SVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQ 471
+ + EE ++ + L+ N L K ++E +A + + +E + +R ++
Sbjct: 63 QADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT 121
Query: 472 TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI 531
+ + L E+ K E+ ++ LE + K + +L E+E K I+ LEA+I
Sbjct: 122 QQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 181
Query: 532 KDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
+E ++++E R K L++K+++LKE+++Q E+++K ++ EK + V K
Sbjct: 182 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLK 241
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVP 646
RQL E E SQ+ R+ QREL+ A + + ++ +++K R TS VP
Sbjct: 242 RQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 296
Score = 48.4 bits (110), Expect = 8e-05
Identities = 57/287 (19%), Positives = 121/287 (42%), Gaps = 8/287 (2%)
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
R +E + E+ K+ + + LE L + ++ K+ L+ E+
Sbjct: 17 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELA 76
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELT 429
D+ + RI L E+EE +GN E + RV+++ +Q + S E T
Sbjct: 77 SSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERT 136
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
N S++ ++E++ + + E+ ++ +++ L+ + L E+ E+
Sbjct: 137 TAQKN-ESARQQLERQNKELRSKLHEMEGAVK---SKFKSTIAALEAKIAQLEEQVEQEA 192
Query: 490 KI-EAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELELDEEKRRHA 546
+ +A KSL+ + K + L +VE + K K A +K ++ +L+E +
Sbjct: 193 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLEEAEEESQ 252
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
RK +R+L E E + ++ L+ L + ++ + R+
Sbjct: 253 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRR 299
>BC007877-1|AAH07877.2| 256|Homo sapiens MYH14 protein protein.
Length = 256
Score = 106 bits (254), Expect = 3e-22
Identities = 64/225 (28%), Positives = 122/225 (54%), Gaps = 1/225 (0%)
Query: 439 KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
K ++E L + + +E + ++RY+++ +++ L E+ K E+ ++ L
Sbjct: 9 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 68
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
E +++ + RL E +A A K I+ LE+++ E +L++E R + K++R+ E++
Sbjct: 69 ERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKR 128
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
LKEV++Q EE+++ L+D LEK + +V KRQL E E + ++ RR QRELE
Sbjct: 129 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 188
Query: 619 EDRADVAESNLSLIRAK-HRTFVTTSTVPGSQVYLVQESRALSSE 662
+ A+ ++ +R + R +T +T QV+ ++E A E
Sbjct: 189 TESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 233
Score = 51.2 bits (117), Expect = 1e-05
Identities = 43/193 (22%), Positives = 91/193 (47%), Gaps = 7/193 (3%)
Query: 361 QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEE 420
+L +++ +E Q ++ D+Y +++SLT E+ R +A ++ +E+Q +E
Sbjct: 15 RLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQE 74
Query: 421 SQTRVNELTV-INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVE 479
+ R+ E + A +E +LA ++ T+E ++ + +R + LK V
Sbjct: 75 LRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVL 134
Query: 480 HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV--EANAIVGGKRIISKLEARIKDMELE 537
+ EE+ ++ + + VK + +LEE EA+ G+R +L+ ++D+ E
Sbjct: 135 QVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRR---RLQRELEDV-TE 190
Query: 538 LDEEKRRHAETIK 550
E R T++
Sbjct: 191 SAESMNREVTTLR 203
>S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 296
Score = 104 bits (249), Expect = 1e-21
Identities = 65/286 (22%), Positives = 141/286 (49%), Gaps = 2/286 (0%)
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K ++K Q+ + Q ++ + +++ +SL ++ +++ + A R ++
Sbjct: 3 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 62
Query: 413 SVEQQYEE-SQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQ 471
+ + EE ++ + L+ N L K ++E +A + + +E + +R ++
Sbjct: 63 QADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT 121
Query: 472 TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI 531
+ + L E+ K E+ ++ LE + K + +L E+E K I+ LEA+I
Sbjct: 122 QQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 181
Query: 532 KDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
+E ++++E R K L++K+++LKE+++Q E+++K ++ EK + V K
Sbjct: 182 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLK 241
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
RQL E E SQ+ R+ QREL+ A + + ++ +++K R
Sbjct: 242 RQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 287
>AL132825-5|CAI43044.1| 149|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 149
Score = 103 bits (248), Expect = 2e-21
Identities = 46/107 (42%), Positives = 76/107 (71%)
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
++++E ELD E+++HAE +K +RK ER++KE+ Q EED+KN++ +QD ++K KV Y
Sbjct: 1 VRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSY 60
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
KRQ E E + ++ + R+ Q EL+ AE+RAD+AE+ + +RA+ R
Sbjct: 61 KRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTR 107
>AL132825-4|CAI43043.1| 122|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 122
Score = 103 bits (248), Expect = 2e-21
Identities = 46/107 (42%), Positives = 76/107 (71%)
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
++++E ELD E+++HAE +K +RK ER++KE+ Q EED+KN++ +QD ++K KV Y
Sbjct: 1 VRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSY 60
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
KRQ E E + ++ + R+ Q EL+ AE+RAD+AE+ + +RA+ R
Sbjct: 61 KRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTR 107
>AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22037 fis, clone HEP08868. ).
Length = 746
Score = 97.1 bits (231), Expect = 2e-19
Identities = 101/484 (20%), Positives = 226/484 (46%), Gaps = 50/484 (10%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITE 245
LEE + K + + + RD L + LAK E +A+ D +V ++T
Sbjct: 118 LEEEEGMAASLSAAKRKLEGELSDLKRDLEGL-ETTLAKTEKEKQAL---DHKV-RTLTG 172
Query: 246 TVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEI 305
+ +RE S + ++ E A++ + L++L Q ++ V L ++ + S +I
Sbjct: 173 DLSLREDS----ITKLQKEKRALEELHQKTLDDL-----QAEEDKVNHLTKNNSKLSTQI 223
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
+L E E K+++EV + ++K + + +L+ ++ +DL++ +KK+ L++ +
Sbjct: 224 HELEDNW-EQEKKIRAEVEKARRKAESDLKMTIDNLNEMERSKLDLEEVVKKRDLEINSV 282
Query: 366 QTHYDE-------VQRQLQVTLDQYGVAQRRIQ---SLTGEVEEIRGNYEQALRVKRSVE 415
+ Y++ +QR+L+ D+ + ++ ++ ++E+ R + L+++R +E
Sbjct: 283 NSKYEDEQSLNSTLQRKLKEHQDRIEELEEELEAERAMRAKIEQNRKREAELLKLRRELE 342
Query: 416 QQYEESQTRVN-----------ELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ +S+ + ELT +L K+K+E++ ++ A+ D++ +
Sbjct: 343 EAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEKDKQVMKAEIDDLNASMETIQ 402
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIE-------AVKKSLEIEVKNISVRLEEVEA--N 515
+ + ++ + L E ++ ++E A++ L+ E +S EE ++ N
Sbjct: 403 KSKMNAEAHVRKLEDSLSEANAKVAELERNQAEINAIRTRLQAENSELSREYEESQSRLN 462
Query: 516 AIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL 575
I+ RI + L +++ D + +LDEE + + + L + L V Q EE+Q S
Sbjct: 463 QIL---RIKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQLEEEQGGKSE 519
Query: 576 LQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV-RRFQRELEAAEDRADVAESN-LSLIR 633
LQ + K + +V+ ++ + + + R+ L+ AE+ A+ A++ SL +
Sbjct: 520 LQRLVSKLNTEVTTWRTKYETDAIQRTEELEETKRKLAARLQEAEEAAETAQARAASLEK 579
Query: 634 AKHR 637
K R
Sbjct: 580 NKQR 583
Score = 80.6 bits (190), Expect = 2e-14
Identities = 76/393 (19%), Positives = 196/393 (49%), Gaps = 21/393 (5%)
Query: 251 ETSPTTCVVRINTELPAIDNSY---LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQ 307
+ P V R E+ A + + Q EL VK+ ++ + L+ +I+++
Sbjct: 27 KVKPLLNVARQEEEMKAKEEELRKAMAQTQELVNKVKELEEKTA-TLSQEKNDLTIQLQA 85
Query: 308 LNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQT 367
+++AE +L + + + K L+ QI+++ L+ L +K +L++++
Sbjct: 86 EQENLMDAEERL-TWMMKTKMDLESQISDMRERLEEEEGMAASLSAAKRKLEGELSDLKR 144
Query: 368 HYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN- 426
+ ++ L T + ++++LTG++ + + + KR++E+ ++++ +
Sbjct: 145 DLEGLETTLAKTEKEKQALDHKVRTLTGDLSLREDSITKLQKEKRALEELHQKTLDDLQA 204
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR-VQTELKHTVEHLHEEQ 485
E +N +L+ + +K+ ++ + ++++ K++R E+ +R +++LK T+++L+E +
Sbjct: 205 EEDKVN-HLTKNNSKLSTQIHELEDNWEQ-EKKIRAEVEKARRKAESDLKMTIDNLNEME 262
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEA-NAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ +E V K ++E+ +++ + E+ ++ N+ + +R + + + RI+++E EL+ E+
Sbjct: 263 RSKLDLEEVVKKRDLEINSVNSKYEDEQSLNSTL--QRKLKEHQDRIEELEEELEAERAM 320
Query: 545 HAETIKILRKKE-------RQLKEVIIQCEEDQKNISLLQ-DSLEKTSQKVSIYKRQLAE 596
A+ I+ RK+E R+L+E +Q E + DS+ + ++ V +R ++
Sbjct: 321 RAK-IEQNRKREAELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSK 379
Query: 597 QEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
E Q + +E + AE+++
Sbjct: 380 LEKDKQVMKAEIDDLNASMETIQKSKMNAEAHV 412
Score = 75.4 bits (177), Expect = 6e-13
Identities = 83/362 (22%), Positives = 165/362 (45%), Gaps = 20/362 (5%)
Query: 192 NVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKA-MNSCDSRVTESITETVRVR 250
N E + K A + + + N L ++A +N+ +R+ +E R
Sbjct: 395 NASMETIQKSKMNAEAHVRKLEDSLSEANAKVAELERNQAEINAIRTRLQAENSELSREY 454
Query: 251 ETSPTTC--VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQL 308
E S + ++RI T L + + Y QL+E ++ +V L ++ + EQL
Sbjct: 455 EESQSRLNQILRIKTSLTSQVDDYKRQLDEESKS----RSTAVVSLANTKHDLDLVKEQL 510
Query: 309 NARVVEAETKLKSEVTRIKKKLQIQIT--ELELSLDVANKTNIDLQKTIKKQSLQLTEIQ 366
E E KSE+ R+ KL ++T + D +T +L++T +K + +L E +
Sbjct: 511 -----EEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRTE-ELEETKRKLAARLQEAE 564
Query: 367 THYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN 426
+ Q + Q ++ LT ++E+ + +R ++ E Q +
Sbjct: 565 EAAETAQARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKCE 624
Query: 427 ELTVINVNLSSSKAKIEQ-ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
EL V V+ S + ++ E + Y+E + L + + +Q E+K ++ L E
Sbjct: 625 ELQV-EVDSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGG 683
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS-KLE-ARIK-DMELELDEEK 542
+ +++ +KK LE+E + + V LEE E++ V ++I +LE A++K D++ + E+K
Sbjct: 684 RSVHELQKLKKKLEMEKEELQVALEEAESSLEVEESKVIRIQLELAQVKADIDRRIHEKK 743
Query: 543 RR 544
++
Sbjct: 744 KK 745
Score = 60.5 bits (140), Expect = 2e-08
Identities = 99/498 (19%), Positives = 208/498 (41%), Gaps = 52/498 (10%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
KKR EI YE E +L S L++K + Q +EE ++ ER +
Sbjct: 273 KKRDLEINSVNSKYEDEQSLNSTLQRKLKEH---------QDRIEELEEELEAERAMRAK 323
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITE-TVRVRETSPTTCVVRI 261
+ +R + L + + AL ++ + +S+ E T V +
Sbjct: 324 IEQNRKR-EAELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEK 382
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS 321
+ ++ + LN E + K + V L DS + + NA+V E E + ++
Sbjct: 383 DKQVMKAEIDDLNASMETIQKSKMNAEAHVRKLEDS-------LSEANAKVAELE-RNQA 434
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
E+ I+ +LQ + +EL + +++ ++ IK T + + D+ +RQL
Sbjct: 435 EINAIRTRLQAENSELSREYE-ESQSRLNQILRIK------TSLTSQVDDYKRQLDEESK 487
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
A + + +++ ++ E+ K E Q V++L N +++ + K
Sbjct: 488 SRSTAVVSLANTKHDLDLVKEQLEEEQGGK-------SELQRLVSKL---NTEVTTWRTK 537
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
E D + T+EL +E +++ L+ E Q R +E K+ L+ E
Sbjct: 538 YE-------TDAIQRTEEL---EETKRKLAARLQEAEEAAETAQARAASLEKNKQRLQAE 587
Query: 502 VKNISVRLEEVEANAIVGGK------RIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
V+++++ LE+ A A K +++++ + + +++++E+D ++ + K
Sbjct: 588 VEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKCEELQVEVDSSQKECRMYMTESFKI 647
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ +E + E +K LQ+ ++ ++ R + E + + ++ Q L
Sbjct: 648 KTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVHELQKLKKKLEMEKEELQVAL 707
Query: 616 EAAEDRADVAESNLSLIR 633
E AE +V ES + I+
Sbjct: 708 EEAESSLEVEESKVIRIQ 725
>AF149209-1|AAF73155.1| 167|Homo sapiens extraocular myosin heavy
chain protein.
Length = 167
Score = 96.7 bits (230), Expect = 2e-19
Identities = 56/165 (33%), Positives = 92/165 (55%)
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRV 425
Q H D+ R + +Q + +RR L E+EE++ EQ R +R EQ+ ++ RV
Sbjct: 3 QLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRV 62
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
L N +L ++K K+E ++A A+ + +E R A+E+ ++ T+ E L +EQ
Sbjct: 63 QLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQ 122
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
+ +E +KK+LE VK++ RL+E E A+ GGK+ I KLE R
Sbjct: 123 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENR 167
Score = 31.9 bits (69), Expect = 7.5
Identities = 29/128 (22%), Positives = 60/128 (46%), Gaps = 8/128 (6%)
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR---RHAET 548
E +K+ L I + + LEE+E + + ++ R+ + EL LD R H++
Sbjct: 14 EDLKEQLAIVERRNGLLLEELEEMKVALEQ---TERTRRLSEQEL-LDASDRVQLLHSQN 69
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
++ K++ L+ I QC+ + +N + E+ ++K +AE+ Q + +
Sbjct: 70 TSLINTKKK-LEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHL 128
Query: 609 RRFQRELE 616
R ++ LE
Sbjct: 129 ERMKKNLE 136
>X04627-1|CAA28300.1| 258|Homo sapiens beta-myosin heavy chain
protein.
Length = 258
Score = 94.7 bits (225), Expect = 9e-19
Identities = 67/231 (29%), Positives = 122/231 (52%), Gaps = 17/231 (7%)
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQ---RVQTEL 474
Y + + RV LT L AK+ +E + + + +L+ +++ + + +L
Sbjct: 32 YGDFRQRVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKL 91
Query: 475 KHTVEHLHE--EQERIVK--IEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
+ V+ L EQE+ V+ +E K+ LE ++K + ++E + +L+ R
Sbjct: 92 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK--------QQLDER 143
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+K + EL+ R + + + +++LKE +Q EED+KN+ LQD ++K KV Y
Sbjct: 144 LKKKDFELNALNARIEDEQALGSQLQKKLKE--LQTEEDRKNLLRLQDLVDKLQLKVKAY 201
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
KRQ E E + ++++ R+ Q EL+ AE+RAD+AES ++ +RAK R T
Sbjct: 202 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGT 252
Score = 46.4 bits (105), Expect = 3e-04
Identities = 47/235 (20%), Positives = 104/235 (44%), Gaps = 13/235 (5%)
Query: 272 YLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
+ ++ L E + D++ + + K+ E Q ++AE + +T+ K KL+
Sbjct: 35 FRQRVKNLTEEMAGLDEIIAKLTKE--KKALQEAHQQALDDLQAEEDKVNTLTKAKVKLE 92
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
Q+ +LE SL+ K +DL++ +K L Q +++ Q ++ +
Sbjct: 93 QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELN 152
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
+L +E+ EQAL ++++ +E QT + ++ L K++ ++
Sbjct: 153 ALNARIED-----EQAL--GSQLQKKLKELQTEEDRKNLL--RLQDLVDKLQLKVKAYKR 203
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNIS 506
+E ++ ++++VQ EL E + ++ K+ A KS +I K ++
Sbjct: 204 QAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA--KSRDIGTKGLN 256
Score = 44.8 bits (101), Expect = 0.001
Identities = 44/217 (20%), Positives = 103/217 (47%), Gaps = 15/217 (6%)
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG-EVEEIRGNYEQALRVKRSVEQQYEE 420
LTE DE+ +L T ++ + + Q+L + EE + N +VK +EQQ ++
Sbjct: 42 LTEEMAGLDEIIAKL--TKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK--LEQQVDD 97
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
+ + + + ++L +K K+E +L + ++ + + DER ++ EL
Sbjct: 98 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNAR 157
Query: 481 LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDE 540
+ +EQ A+ L+ ++K + + EE N ++ + ++ KL+ ++K + + +E
Sbjct: 158 IEDEQ-------ALGSQLQKKLKEL--QTEEDRKN-LLRLQDLVDKLQLKVKAYKRQAEE 207
Query: 541 EKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
+ + + RK + +L E + + + ++ L+
Sbjct: 208 AEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLR 244
>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
Length = 1047
Score = 89.4 bits (212), Expect = 4e-17
Identities = 83/406 (20%), Positives = 194/406 (47%), Gaps = 21/406 (5%)
Query: 245 ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLS--VYILNDSSKQTS 302
E ++ E + + E+ ++ + ++ E KE V L + + QT+
Sbjct: 598 EDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTT 657
Query: 303 IEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
E +QL+ ++ E E++ K ++ R+K +++ + L +++ K D+ + + +L+L
Sbjct: 658 QEQKQLSEKLKE-ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLEL 716
Query: 363 TEIQTHYDE--------VQRQLQ---VTLDQYGVAQRRIQSLTGEVEEIRGNYE----QA 407
Y E +QRQL+ + ++ + ++Q +EE +Y+ +A
Sbjct: 717 QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA 776
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERY 467
L ++ +EQ ++ + + + + + S ++E +++ + + +E + ER
Sbjct: 777 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 836
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
R + +++ L +E+ +E K SLE + K++ R+ +E + + ++ ++
Sbjct: 837 SRSREQMEQVRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQM 896
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
EARI ++E L+ E+R A R+ ER++KE+++Q +++ + L D ++ S ++
Sbjct: 897 EARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS---LTDQKDQLSLRL 953
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
KRQ+ E E + + ++ QRELE D + + L+ ++
Sbjct: 954 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMK 999
Score = 68.1 bits (159), Expect = 9e-11
Identities = 100/484 (20%), Positives = 211/484 (43%), Gaps = 36/484 (7%)
Query: 142 QKKRMQEIEKEL-DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
+++RM+ +EL + ++V S L+Q+ G+ K + + + R +
Sbjct: 388 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 447
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSR----VTESITETVRVRETSPTT 256
Q S D S++ AL+E D + E + +R RE T
Sbjct: 448 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 507
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ E+ + D ++++LKE Q+D + L +S ++ + +E L +R +E
Sbjct: 508 LKGALKEEVSSHDQ----EMDKLKE---QYD-AELQALRESVEEATKNVEVLASRSNTSE 559
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI---KKQSLQLTEIQTHYDEVQ 373
R+K LQ + +L+ + + LQ+ I K + E Y+
Sbjct: 560 QDQAGTEMRVKL-LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEI 618
Query: 374 RQLQVTL------DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY-EESQTRV- 425
RQL+ L ++ V+ RR +L E+E +GN Q + ++ + ++ EES+ +
Sbjct: 619 RQLEEALVHARKEEKEAVSARR--ALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQ 676
Query: 426 -----NELTVINVNLSSSKAKIEQELAIVAADYDEITKELR-IADERYQRVQTELKHTVE 479
NE+ +L + K+++E+A + T EL+ DE ++ + EL
Sbjct: 677 LRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQR 736
Query: 480 HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE-ANAIVGGKRIISKLEARIKDMELEL 538
L E+ K ++ E++ + L + + A KR + LE +KD+E EL
Sbjct: 737 QLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQL--LEQTLKDLEYEL 794
Query: 539 DEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
+ + + +++++ E ++ ++ ++ EE++ N LL + + ++ +++ + +L ++
Sbjct: 795 EAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQVRNELLQER 854
Query: 599 GMSQ 602
Q
Sbjct: 855 AARQ 858
Score = 51.6 bits (118), Expect = 9e-06
Identities = 80/413 (19%), Positives = 180/413 (43%), Gaps = 42/413 (10%)
Query: 248 RVRETSPTTCVVRINTE-LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
R TSP + +I+ + P+ N+ + +K +L+ +++KQ I
Sbjct: 254 RAAATSPDSGAKKISVKTFPSASNTQATP-----DLLKGQQELTQQTNEETAKQ--ILYN 306
Query: 307 QLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQ 366
L + + K +V + +K+Q + S N + +K Q +++
Sbjct: 307 YLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQ-GNNQACNSTSEVKDLLEQKSKLT 365
Query: 367 THYDEVQRQLQVTL-DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ--- 422
E+QRQLQ+ + +Q + + R + + +EE+R + + + +++Q+ EES+
Sbjct: 366 IEVAELQRQLQLEVKNQQNIKEER-ERMRANLEELRSQHNEKVEENSTLQQRLEESEGEL 424
Query: 423 -TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
+ EL + + + +I ++ +DE+ R D + EL + L
Sbjct: 425 RKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDL 484
Query: 482 H------EEQERIVK-----IEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
EEQE +++ + A+K +L+ EV + +++++ + + +E
Sbjct: 485 QDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEA 544
Query: 531 IKDMEL-----ELDEEKRRHAE-TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS 584
K++E+ E+ + E +K+L+++ +L+ + EE ++ ++ LQ +E
Sbjct: 545 TKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQG---RSEELERRVAQLQRQIEDLK 601
Query: 585 QKVSIYKRQLAEQEG---MSQQSVTRVRRFQREL----EAAEDRADVAESNLS 630
+ K L + EG ++++ R+ ++E A E+ + A+ NLS
Sbjct: 602 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLS 654
Score = 48.8 bits (111), Expect = 6e-05
Identities = 83/395 (21%), Positives = 179/395 (45%), Gaps = 31/395 (7%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+L + N N+ L +T+++ I+ ++S+ +++E++ ++ E + K + E+
Sbjct: 676 QLRRLKNEMENERWHLGKTIEKLQKEMADIV-EASRTSTLELQN---QLDEYKEKNRREL 731
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++++L+ + E E S A K +Q ++ +L + Q DE + Q+
Sbjct: 732 AEMQRQLKEKTLEAEKSRLTAMK----MQDEMRLMEEELRDYQRAQDEALTKRQLLEQTL 787
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ +++ + +++ R + + K S +E + EE + N +++ +S S+ ++
Sbjct: 788 KDLEYELEAKS-HLKDDRSRLVKQMEDKVSQLEMELEEER---NNSDLLSERISRSREQM 843
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
EQ + + ++L +R +LK + HL E R K E + +E +
Sbjct: 844 EQVRNELLQER-AARQDLECDKISLERQNKDLKSRIIHL-EGSYRSSK-EGLVVQMEARI 900
Query: 503 KNISVRLEEVE---ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ RLE E AN + +R LE ++K++ +++D+E H + +L
Sbjct: 901 AELEDRLESEERDRANLQLSNRR----LERKVKELVMQVDDE---HLSLTDQKDQLSLRL 953
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM--SQQSVTRVRRF-QRELE 616
K + Q EE ++ I L+ S +K +++ +G S + R+++ + L+
Sbjct: 954 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLD 1013
Query: 617 AAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQV 650
+D D++ SL A TF STV SQ+
Sbjct: 1014 DMDDDDDLSTDGGSLYEAPVSYTFSKDSTV-ASQI 1047
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/241 (20%), Positives = 110/241 (45%), Gaps = 22/241 (9%)
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
S + V +L L+ A+++++L + + I +E + ++++ VE
Sbjct: 350 STSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEE 409
Query: 481 LHEEQERIVKIEA-VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELD 539
Q+R+ + E ++K+LE E+ + + E+ + I L+ ++ +M ELD
Sbjct: 410 NSTLQQRLEESEGELRKNLE-ELFQVKMEREQHQTE--------IRDLQDQLSEMHDELD 460
Query: 540 EEKRRH----AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
KR I+ L + ++ L++++I EE + D L K ++++ K L
Sbjct: 461 SAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQE-------DLLRKRERELTALKGALK 513
Query: 596 EQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQ 654
E+ Q + +++ ++ EL+A + + A N+ ++ ++ T +V L+Q
Sbjct: 514 EEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQ 573
Query: 655 E 655
E
Sbjct: 574 E 574
>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 89.0 bits (211), Expect = 5e-17
Identities = 83/406 (20%), Positives = 194/406 (47%), Gaps = 21/406 (5%)
Query: 245 ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLS--VYILNDSSKQTS 302
E ++ E + + E+ ++ + ++ E KE V L + + QT+
Sbjct: 853 EDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTT 912
Query: 303 IEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
E +QL+ ++ E E++ K ++ R+K +++ + L +++ K D+ + + +L+L
Sbjct: 913 QEQKQLSEKLKE-ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLEL 971
Query: 363 TEIQTHYDE--------VQRQLQ---VTLDQYGVAQRRIQSLTGEVEEIRGNYE----QA 407
Y E +QRQL+ + ++ + ++Q +EE +Y+ +A
Sbjct: 972 QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA 1031
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERY 467
L ++ +EQ ++ + + + + + S ++E +++ + + +E + ER
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
R + +++ L +E+ +E K SLE + K++ R+ +E + + ++ ++
Sbjct: 1092 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQM 1151
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
EARI ++E L+ E+R A R+ ER++KE+++Q +++ + L D ++ S ++
Sbjct: 1152 EARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS---LTDQKDQLSLRL 1208
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
KRQ+ E E + + ++ QRELE D + + L+ ++
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMK 1254
Score = 68.1 bits (159), Expect = 9e-11
Identities = 100/484 (20%), Positives = 211/484 (43%), Gaps = 36/484 (7%)
Query: 142 QKKRMQEIEKEL-DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
+++RM+ +EL + ++V S L+Q+ G+ K + + + R +
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSR----VTESITETVRVRETSPTT 256
Q S D S++ AL+E D + E + +R RE T
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ E+ + D ++++LKE Q+D + L +S ++ + +E L +R +E
Sbjct: 763 LKGALKEEVSSHDQ----EMDKLKE---QYD-AELQALRESVEEATKNVEVLASRSNTSE 814
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI---KKQSLQLTEIQTHYDEVQ 373
R+K LQ + +L+ + + LQ+ I K + E Y+
Sbjct: 815 QDQAGTEMRVKL-LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEI 873
Query: 374 RQLQVTL------DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY-EESQTRV- 425
RQL+ L ++ V+ RR +L E+E +GN Q + ++ + ++ EES+ +
Sbjct: 874 RQLEEALVHARKEEKEAVSARR--ALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQ 931
Query: 426 -----NELTVINVNLSSSKAKIEQELAIVAADYDEITKELR-IADERYQRVQTELKHTVE 479
NE+ +L + K+++E+A + T EL+ DE ++ + EL
Sbjct: 932 LRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQR 991
Query: 480 HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE-ANAIVGGKRIISKLEARIKDMELEL 538
L E+ K ++ E++ + L + + A KR + LE +KD+E EL
Sbjct: 992 QLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQL--LEQTLKDLEYEL 1049
Query: 539 DEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
+ + + +++++ E ++ ++ ++ EE++ N LL + + ++ +++ + +L ++
Sbjct: 1050 EAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQER 1109
Query: 599 GMSQ 602
Q
Sbjct: 1110 AARQ 1113
Score = 51.6 bits (118), Expect = 9e-06
Identities = 80/413 (19%), Positives = 180/413 (43%), Gaps = 42/413 (10%)
Query: 248 RVRETSPTTCVVRINTE-LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
R TSP + +I+ + P+ N+ + +K +L+ +++KQ I
Sbjct: 509 RAAATSPDSGAKKISVKTFPSASNTQATP-----DLLKGQQELTQQTNEETAKQ--ILYN 561
Query: 307 QLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQ 366
L + + K +V + +K+Q + S N + +K Q +++
Sbjct: 562 YLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQ-GNNQACNSTSEVKDLLEQKSKLT 620
Query: 367 THYDEVQRQLQVTL-DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ--- 422
E+QRQLQ+ + +Q + + R + + +EE+R + + + +++Q+ EES+
Sbjct: 621 IEVAELQRQLQLEVKNQQNIKEER-ERMRANLEELRSQHNEKVEENSTLQQRLEESEGEL 679
Query: 423 -TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
+ EL + + + +I ++ +DE+ R D + EL + L
Sbjct: 680 RKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDL 739
Query: 482 H------EEQERIVK-----IEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
EEQE +++ + A+K +L+ EV + +++++ + + +E
Sbjct: 740 QDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEA 799
Query: 531 IKDMEL-----ELDEEKRRHAE-TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS 584
K++E+ E+ + E +K+L+++ +L+ + EE ++ ++ LQ +E
Sbjct: 800 TKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQG---RSEELERRVAQLQRQIEDLK 856
Query: 585 QKVSIYKRQLAEQEG---MSQQSVTRVRRFQREL----EAAEDRADVAESNLS 630
+ K L + EG ++++ R+ ++E A E+ + A+ NLS
Sbjct: 857 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLS 909
Score = 49.6 bits (113), Expect = 3e-05
Identities = 84/395 (21%), Positives = 178/395 (45%), Gaps = 31/395 (7%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+L + N N+ L +T+++ I+ ++S+ +++E++ ++ E + K + E+
Sbjct: 931 QLRRLKNEMENERWHLGKTIEKLQKEMADIV-EASRTSTLELQN---QLDEYKEKNRREL 986
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++++L+ + E E S A K +Q ++ +L + Q DE + Q+
Sbjct: 987 AEMQRQLKEKTLEAEKSRLTAMK----MQDEMRLMEEELRDYQRAQDEALTKRQLLEQTL 1042
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ +++ + +++ R + + K S +E + EE + N +++ +S S+ ++
Sbjct: 1043 KDLEYELEAKS-HLKDDRSRLVKQMEDKVSQLEMELEEER---NNSDLLSERISRSREQM 1098
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
EQ L ++L +R +LK + HL E R K E + +E +
Sbjct: 1099 EQ-LRNELLQERAARQDLECDKISLERQNKDLKSRIIHL-EGSYRSSK-EGLVVQMEARI 1155
Query: 503 KNISVRLEEVE---ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ RLE E AN + +R LE ++K++ +++D+E H + +L
Sbjct: 1156 AELEDRLESEERDRANLQLSNRR----LERKVKELVMQVDDE---HLSLTDQKDQLSLRL 1208
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM--SQQSVTRVRRF-QRELE 616
K + Q EE ++ I L+ S +K +++ +G S + R+++ + L+
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLD 1268
Query: 617 AAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQV 650
+D D++ SL A TF STV SQ+
Sbjct: 1269 DMDDDDDLSTDGGSLYEAPVSYTFSKDSTV-ASQI 1302
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/241 (20%), Positives = 110/241 (45%), Gaps = 22/241 (9%)
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
S + V +L L+ A+++++L + + I +E + ++++ VE
Sbjct: 605 STSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEE 664
Query: 481 LHEEQERIVKIEA-VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELD 539
Q+R+ + E ++K+LE E+ + + E+ + I L+ ++ +M ELD
Sbjct: 665 NSTLQQRLEESEGELRKNLE-ELFQVKMEREQHQTE--------IRDLQDQLSEMHDELD 715
Query: 540 EEKRRH----AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
KR I+ L + ++ L++++I EE + D L K ++++ K L
Sbjct: 716 SAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQE-------DLLRKRERELTALKGALK 768
Query: 596 EQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQ 654
E+ Q + +++ ++ EL+A + + A N+ ++ ++ T +V L+Q
Sbjct: 769 EEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQ 828
Query: 655 E 655
E
Sbjct: 829 E 829
>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 89.0 bits (211), Expect = 5e-17
Identities = 83/406 (20%), Positives = 194/406 (47%), Gaps = 21/406 (5%)
Query: 245 ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLS--VYILNDSSKQTS 302
E ++ E + + E+ ++ + ++ E KE V L + + QT+
Sbjct: 853 EDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTT 912
Query: 303 IEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
E +QL+ ++ E E++ K ++ R+K +++ + L +++ K D+ + + +L+L
Sbjct: 913 QEQKQLSEKLKE-ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLEL 971
Query: 363 TEIQTHYDE--------VQRQLQ---VTLDQYGVAQRRIQSLTGEVEEIRGNYE----QA 407
Y E +QRQL+ + ++ + ++Q +EE +Y+ +A
Sbjct: 972 QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA 1031
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERY 467
L ++ +EQ ++ + + + + + S ++E +++ + + +E + ER
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
R + +++ L +E+ +E K SLE + K++ R+ +E + + ++ ++
Sbjct: 1092 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQM 1151
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
EARI ++E L+ E+R A R+ ER++KE+++Q +++ + L D ++ S ++
Sbjct: 1152 EARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS---LTDQKDQLSLRL 1208
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
KRQ+ E E + + ++ QRELE D + + L+ ++
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMK 1254
Score = 68.1 bits (159), Expect = 9e-11
Identities = 100/484 (20%), Positives = 211/484 (43%), Gaps = 36/484 (7%)
Query: 142 QKKRMQEIEKEL-DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
+++RM+ +EL + ++V S L+Q+ G+ K + + + R +
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSR----VTESITETVRVRETSPTT 256
Q S D S++ AL+E D + E + +R RE T
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ E+ + D ++++LKE Q+D + L +S ++ + +E L +R +E
Sbjct: 763 LKGALKEEVSSHDQ----EMDKLKE---QYD-AELQALRESVEEATKNVEVLASRSNTSE 814
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI---KKQSLQLTEIQTHYDEVQ 373
R+K LQ + +L+ + + LQ+ I K + E Y+
Sbjct: 815 QDQAGTEMRVKL-LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEI 873
Query: 374 RQLQVTL------DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY-EESQTRV- 425
RQL+ L ++ V+ RR +L E+E +GN Q + ++ + ++ EES+ +
Sbjct: 874 RQLEEALVHARKEEKEAVSARR--ALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQ 931
Query: 426 -----NELTVINVNLSSSKAKIEQELAIVAADYDEITKELR-IADERYQRVQTELKHTVE 479
NE+ +L + K+++E+A + T EL+ DE ++ + EL
Sbjct: 932 LRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQR 991
Query: 480 HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE-ANAIVGGKRIISKLEARIKDMELEL 538
L E+ K ++ E++ + L + + A KR + LE +KD+E EL
Sbjct: 992 QLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQL--LEQTLKDLEYEL 1049
Query: 539 DEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
+ + + +++++ E ++ ++ ++ EE++ N LL + + ++ +++ + +L ++
Sbjct: 1050 EAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQER 1109
Query: 599 GMSQ 602
Q
Sbjct: 1110 AARQ 1113
Score = 51.6 bits (118), Expect = 9e-06
Identities = 80/413 (19%), Positives = 180/413 (43%), Gaps = 42/413 (10%)
Query: 248 RVRETSPTTCVVRINTE-LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
R TSP + +I+ + P+ N+ + +K +L+ +++KQ I
Sbjct: 509 RAAATSPDSGAKKISVKTFPSASNTQATP-----DLLKGQQELTQQTNEETAKQ--ILYN 561
Query: 307 QLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQ 366
L + + K +V + +K+Q + S N + +K Q +++
Sbjct: 562 YLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQ-GNNQACNSTSEVKDLLEQKSKLT 620
Query: 367 THYDEVQRQLQVTL-DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ--- 422
E+QRQLQ+ + +Q + + R + + +EE+R + + + +++Q+ EES+
Sbjct: 621 IEVAELQRQLQLEVKNQQNIKEER-ERMRANLEELRSQHNEKVEENSTLQQRLEESEGEL 679
Query: 423 -TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
+ EL + + + +I ++ +DE+ R D + EL + L
Sbjct: 680 RKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDL 739
Query: 482 H------EEQERIVK-----IEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
EEQE +++ + A+K +L+ EV + +++++ + + +E
Sbjct: 740 QDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEA 799
Query: 531 IKDMEL-----ELDEEKRRHAE-TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS 584
K++E+ E+ + E +K+L+++ +L+ + EE ++ ++ LQ +E
Sbjct: 800 TKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQG---RSEELERRVAQLQRQIEDLK 856
Query: 585 QKVSIYKRQLAEQEG---MSQQSVTRVRRFQREL----EAAEDRADVAESNLS 630
+ K L + EG ++++ R+ ++E A E+ + A+ NLS
Sbjct: 857 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLS 909
Score = 49.6 bits (113), Expect = 3e-05
Identities = 84/395 (21%), Positives = 178/395 (45%), Gaps = 31/395 (7%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+L + N N+ L +T+++ I+ ++S+ +++E++ ++ E + K + E+
Sbjct: 931 QLRRLKNEMENERWHLGKTIEKLQKEMADIV-EASRTSTLELQN---QLDEYKEKNRREL 986
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++++L+ + E E S A K +Q ++ +L + Q DE + Q+
Sbjct: 987 AEMQRQLKEKTLEAEKSRLTAMK----MQDEMRLMEEELRDYQRAQDEALTKRQLLEQTL 1042
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ +++ + +++ R + + K S +E + EE + N +++ +S S+ ++
Sbjct: 1043 KDLEYELEAKS-HLKDDRSRLVKQMEDKVSQLEMELEEER---NNSDLLSERISRSREQM 1098
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
EQ L ++L +R +LK + HL E R K E + +E +
Sbjct: 1099 EQ-LRNELLQERAARQDLECDKISLERQNKDLKSRIIHL-EGSYRSSK-EGLVVQMEARI 1155
Query: 503 KNISVRLEEVE---ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ RLE E AN + +R LE ++K++ +++D+E H + +L
Sbjct: 1156 AELEDRLESEERDRANLQLSNRR----LERKVKELVMQVDDE---HLSLTDQKDQLSLRL 1208
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM--SQQSVTRVRRF-QRELE 616
K + Q EE ++ I L+ S +K +++ +G S + R+++ + L+
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLD 1268
Query: 617 AAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQV 650
+D D++ SL A TF STV SQ+
Sbjct: 1269 DMDDDDDLSTDGGSLYEAPVSYTFSKDSTV-ASQI 1302
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/241 (20%), Positives = 110/241 (45%), Gaps = 22/241 (9%)
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
S + V +L L+ A+++++L + + I +E + ++++ VE
Sbjct: 605 STSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEE 664
Query: 481 LHEEQERIVKIEA-VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELD 539
Q+R+ + E ++K+LE E+ + + E+ + I L+ ++ +M ELD
Sbjct: 665 NSTLQQRLEESEGELRKNLE-ELFQVKMEREQHQTE--------IRDLQDQLSEMHDELD 715
Query: 540 EEKRRH----AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
KR I+ L + ++ L++++I EE + D L K ++++ K L
Sbjct: 716 SAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQE-------DLLRKRERELTALKGALK 768
Query: 596 EQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQ 654
E+ Q + +++ ++ EL+A + + A N+ ++ ++ T +V L+Q
Sbjct: 769 EEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQ 828
Query: 655 E 655
E
Sbjct: 829 E 829
>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 89.0 bits (211), Expect = 5e-17
Identities = 83/406 (20%), Positives = 194/406 (47%), Gaps = 21/406 (5%)
Query: 245 ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLS--VYILNDSSKQTS 302
E ++ E + + E+ ++ + ++ E KE V L + + QT+
Sbjct: 853 EDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTT 912
Query: 303 IEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
E +QL+ ++ E E++ K ++ R+K +++ + L +++ K D+ + + +L+L
Sbjct: 913 QEQKQLSEKLKE-ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLEL 971
Query: 363 TEIQTHYDE--------VQRQLQ---VTLDQYGVAQRRIQSLTGEVEEIRGNYE----QA 407
Y E +QRQL+ + ++ + ++Q +EE +Y+ +A
Sbjct: 972 QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA 1031
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERY 467
L ++ +EQ ++ + + + + + S ++E +++ + + +E + ER
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
R + +++ L +E+ +E K SLE + K++ R+ +E + + ++ ++
Sbjct: 1092 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQM 1151
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
EARI ++E L+ E+R A R+ ER++KE+++Q +++ + L D ++ S ++
Sbjct: 1152 EARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS---LTDQKDQLSLRL 1208
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
KRQ+ E E + + ++ QRELE D + + L+ ++
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMK 1254
Score = 68.1 bits (159), Expect = 9e-11
Identities = 100/484 (20%), Positives = 211/484 (43%), Gaps = 36/484 (7%)
Query: 142 QKKRMQEIEKEL-DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
+++RM+ +EL + ++V S L+Q+ G+ K + + + R +
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSR----VTESITETVRVRETSPTT 256
Q S D S++ AL+E D + E + +R RE T
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ E+ + D ++++LKE Q+D + L +S ++ + +E L +R +E
Sbjct: 763 LKGALKEEVSSHDQ----EMDKLKE---QYD-AELQALRESVEEATKNVEVLASRSNTSE 814
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI---KKQSLQLTEIQTHYDEVQ 373
R+K LQ + +L+ + + LQ+ I K + E Y+
Sbjct: 815 QDQAGTEMRVKL-LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEI 873
Query: 374 RQLQVTL------DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY-EESQTRV- 425
RQL+ L ++ V+ RR +L E+E +GN Q + ++ + ++ EES+ +
Sbjct: 874 RQLEEALVHARKEEKEAVSARR--ALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQ 931
Query: 426 -----NELTVINVNLSSSKAKIEQELAIVAADYDEITKELR-IADERYQRVQTELKHTVE 479
NE+ +L + K+++E+A + T EL+ DE ++ + EL
Sbjct: 932 LRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQR 991
Query: 480 HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE-ANAIVGGKRIISKLEARIKDMELEL 538
L E+ K ++ E++ + L + + A KR + LE +KD+E EL
Sbjct: 992 QLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQL--LEQTLKDLEYEL 1049
Query: 539 DEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
+ + + +++++ E ++ ++ ++ EE++ N LL + + ++ +++ + +L ++
Sbjct: 1050 EAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQER 1109
Query: 599 GMSQ 602
Q
Sbjct: 1110 AARQ 1113
Score = 51.6 bits (118), Expect = 9e-06
Identities = 80/413 (19%), Positives = 180/413 (43%), Gaps = 42/413 (10%)
Query: 248 RVRETSPTTCVVRINTE-LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
R TSP + +I+ + P+ N+ + +K +L+ +++KQ I
Sbjct: 509 RAAATSPDSGAKKISVKTFPSASNTQATP-----DLLKGQQELTQQTNEETAKQ--ILYN 561
Query: 307 QLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQ 366
L + + K +V + +K+Q + S N + +K Q +++
Sbjct: 562 YLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQ-GNNQACNSTSEVKDLLEQKSKLT 620
Query: 367 THYDEVQRQLQVTL-DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ--- 422
E+QRQLQ+ + +Q + + R + + +EE+R + + + +++Q+ EES+
Sbjct: 621 IEVAELQRQLQLEVKNQQNIKEER-ERMRANLEELRSQHNEKVEENSTLQQRLEESEGEL 679
Query: 423 -TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
+ EL + + + +I ++ +DE+ R D + EL + L
Sbjct: 680 RKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDL 739
Query: 482 H------EEQERIVK-----IEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
EEQE +++ + A+K +L+ EV + +++++ + + +E
Sbjct: 740 QDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEA 799
Query: 531 IKDMEL-----ELDEEKRRHAE-TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS 584
K++E+ E+ + E +K+L+++ +L+ + EE ++ ++ LQ +E
Sbjct: 800 TKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQG---RSEELERRVAQLQRQIEDLK 856
Query: 585 QKVSIYKRQLAEQEG---MSQQSVTRVRRFQREL----EAAEDRADVAESNLS 630
+ K L + EG ++++ R+ ++E A E+ + A+ NLS
Sbjct: 857 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLS 909
Score = 49.6 bits (113), Expect = 3e-05
Identities = 84/395 (21%), Positives = 178/395 (45%), Gaps = 31/395 (7%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+L + N N+ L +T+++ I+ ++S+ +++E++ ++ E + K + E+
Sbjct: 931 QLRRLKNEMENERWHLGKTIEKLQKEMADIV-EASRTSTLELQN---QLDEYKEKNRREL 986
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++++L+ + E E S A K +Q ++ +L + Q DE + Q+
Sbjct: 987 AEMQRQLKEKTLEAEKSRLTAMK----MQDEMRLMEEELRDYQRAQDEALTKRQLLEQTL 1042
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ +++ + +++ R + + K S +E + EE + N +++ +S S+ ++
Sbjct: 1043 KDLEYELEAKS-HLKDDRSRLVKQMEDKVSQLEMELEEER---NNSDLLSERISRSREQM 1098
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
EQ L ++L +R +LK + HL E R K E + +E +
Sbjct: 1099 EQ-LRNELLQERAARQDLECDKISLERQNKDLKSRIIHL-EGSYRSSK-EGLVVQMEARI 1155
Query: 503 KNISVRLEEVE---ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ RLE E AN + +R LE ++K++ +++D+E H + +L
Sbjct: 1156 AELEDRLESEERDRANLQLSNRR----LERKVKELVMQVDDE---HLSLTDQKDQLSLRL 1208
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM--SQQSVTRVRRF-QRELE 616
K + Q EE ++ I L+ S +K +++ +G S + R+++ + L+
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLD 1268
Query: 617 AAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQV 650
+D D++ SL A TF STV SQ+
Sbjct: 1269 DMDDDDDLSTDGGSLYEAPVSYTFSKDSTV-ASQI 1302
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/241 (20%), Positives = 110/241 (45%), Gaps = 22/241 (9%)
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
S + V +L L+ A+++++L + + I +E + ++++ VE
Sbjct: 605 STSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEE 664
Query: 481 LHEEQERIVKIEA-VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELD 539
Q+R+ + E ++K+LE E+ + + E+ + I L+ ++ +M ELD
Sbjct: 665 NSTLQQRLEESEGELRKNLE-ELFQVKMEREQHQTE--------IRDLQDQLSEMHDELD 715
Query: 540 EEKRRH----AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
KR I+ L + ++ L++++I EE + D L K ++++ K L
Sbjct: 716 SAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQE-------DLLRKRERELTALKGALK 768
Query: 596 EQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQ 654
E+ Q + +++ ++ EL+A + + A N+ ++ ++ T +V L+Q
Sbjct: 769 EEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQ 828
Query: 655 E 655
E
Sbjct: 829 E 829
>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
Length = 1302
Score = 89.0 bits (211), Expect = 5e-17
Identities = 83/406 (20%), Positives = 194/406 (47%), Gaps = 21/406 (5%)
Query: 245 ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLS--VYILNDSSKQTS 302
E ++ E + + E+ ++ + ++ E KE V L + + QT+
Sbjct: 853 EDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTT 912
Query: 303 IEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
E +QL+ ++ E E++ K ++ R+K +++ + L +++ K D+ + + +L+L
Sbjct: 913 QEQKQLSEKLKE-ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLEL 971
Query: 363 TEIQTHYDE--------VQRQLQ---VTLDQYGVAQRRIQSLTGEVEEIRGNYE----QA 407
Y E +QRQL+ + ++ + ++Q +EE +Y+ +A
Sbjct: 972 QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEA 1031
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERY 467
L ++ +EQ ++ + + + + + S ++E +++ + + +E + ER
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
R + +++ L +E+ +E K SLE + K++ R+ +E + + ++ ++
Sbjct: 1092 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQM 1151
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
EARI ++E L+ E+R A R+ ER++KE+++Q +++ + L D ++ S ++
Sbjct: 1152 EARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS---LTDQKDQLSLRL 1208
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
KRQ+ E E + + ++ QRELE D + + L+ ++
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMK 1254
Score = 68.1 bits (159), Expect = 9e-11
Identities = 100/484 (20%), Positives = 211/484 (43%), Gaps = 36/484 (7%)
Query: 142 QKKRMQEIEKEL-DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
+++RM+ +EL + ++V S L+Q+ G+ K + + + R +
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSR----VTESITETVRVRETSPTT 256
Q S D S++ AL+E D + E + +R RE T
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ E+ + D ++++LKE Q+D + L +S ++ + +E L +R +E
Sbjct: 763 LKGALKEEVSSHDQ----EMDKLKE---QYD-AELQALRESVEEATKNVEVLASRSNTSE 814
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI---KKQSLQLTEIQTHYDEVQ 373
R+K LQ + +L+ + + LQ+ I K + E Y+
Sbjct: 815 QDQAGTEMRVKL-LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEI 873
Query: 374 RQLQVTL------DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY-EESQTRV- 425
RQL+ L ++ V+ RR +L E+E +GN Q + ++ + ++ EES+ +
Sbjct: 874 RQLEEALVHARKEEKEAVSARR--ALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQ 931
Query: 426 -----NELTVINVNLSSSKAKIEQELAIVAADYDEITKELR-IADERYQRVQTELKHTVE 479
NE+ +L + K+++E+A + T EL+ DE ++ + EL
Sbjct: 932 LRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQR 991
Query: 480 HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE-ANAIVGGKRIISKLEARIKDMELEL 538
L E+ K ++ E++ + L + + A KR + LE +KD+E EL
Sbjct: 992 QLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQL--LEQTLKDLEYEL 1049
Query: 539 DEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
+ + + +++++ E ++ ++ ++ EE++ N LL + + ++ +++ + +L ++
Sbjct: 1050 EAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQER 1109
Query: 599 GMSQ 602
Q
Sbjct: 1110 AARQ 1113
Score = 51.6 bits (118), Expect = 9e-06
Identities = 80/413 (19%), Positives = 180/413 (43%), Gaps = 42/413 (10%)
Query: 248 RVRETSPTTCVVRINTE-LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
R TSP + +I+ + P+ N+ + +K +L+ +++KQ I
Sbjct: 509 RATATSPDSGAKKISVKTFPSASNTQATP-----DLLKGQQELTQQTNEETAKQ--ILYN 561
Query: 307 QLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQ 366
L + + K +V + +K+Q + S N + +K Q +++
Sbjct: 562 YLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQ-GNNQACNSTSEVKDLLEQKSKLT 620
Query: 367 THYDEVQRQLQVTL-DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ--- 422
E+QRQLQ+ + +Q + + R + + +EE+R + + + +++Q+ EES+
Sbjct: 621 IEVAELQRQLQLEVKNQQNIKEER-ERMRANLEELRSQHNEKVEENSTLQQRLEESEGEL 679
Query: 423 -TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
+ EL + + + +I ++ +DE+ R D + EL + L
Sbjct: 680 RKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDL 739
Query: 482 H------EEQERIVK-----IEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
EEQE +++ + A+K +L+ EV + +++++ + + +E
Sbjct: 740 QDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEA 799
Query: 531 IKDMEL-----ELDEEKRRHAE-TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS 584
K++E+ E+ + E +K+L+++ +L+ + EE ++ ++ LQ +E
Sbjct: 800 TKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQG---RSEELERRVAQLQRQIEDLK 856
Query: 585 QKVSIYKRQLAEQEG---MSQQSVTRVRRFQREL----EAAEDRADVAESNLS 630
+ K L + EG ++++ R+ ++E A E+ + A+ NLS
Sbjct: 857 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLS 909
Score = 49.6 bits (113), Expect = 3e-05
Identities = 84/395 (21%), Positives = 178/395 (45%), Gaps = 31/395 (7%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+L + N N+ L +T+++ I+ ++S+ +++E++ ++ E + K + E+
Sbjct: 931 QLRRLKNEMENERWHLGKTIEKLQKEMADIV-EASRTSTLELQN---QLDEYKEKNRREL 986
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++++L+ + E E S A K +Q ++ +L + Q DE + Q+
Sbjct: 987 AEMQRQLKEKTLEAEKSRLTAMK----MQDEMRLMEEELRDYQRAQDEALTKRQLLEQTL 1042
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ +++ + +++ R + + K S +E + EE + N +++ +S S+ ++
Sbjct: 1043 KDLEYELEAKS-HLKDDRSRLVKQMEDKVSQLEMELEEER---NNSDLLSERISRSREQM 1098
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
EQ L ++L +R +LK + HL E R K E + +E +
Sbjct: 1099 EQ-LRNELLQERAARQDLECDKISLERQNKDLKSRIIHL-EGSYRSSK-EGLVVQMEARI 1155
Query: 503 KNISVRLEEVE---ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ RLE E AN + +R LE ++K++ +++D+E H + +L
Sbjct: 1156 AELEDRLESEERDRANLQLSNRR----LERKVKELVMQVDDE---HLSLTDQKDQLSLRL 1208
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM--SQQSVTRVRRF-QRELE 616
K + Q EE ++ I L+ S +K +++ +G S + R+++ + L+
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLD 1268
Query: 617 AAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQV 650
+D D++ SL A TF STV SQ+
Sbjct: 1269 DMDDDDDLSTDGGSLYEAPVSYTFSKDSTV-ASQI 1302
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/241 (20%), Positives = 110/241 (45%), Gaps = 22/241 (9%)
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
S + V +L L+ A+++++L + + I +E + ++++ VE
Sbjct: 605 STSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEE 664
Query: 481 LHEEQERIVKIEA-VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELD 539
Q+R+ + E ++K+LE E+ + + E+ + I L+ ++ +M ELD
Sbjct: 665 NSTLQQRLEESEGELRKNLE-ELFQVKMEREQHQTE--------IRDLQDQLSEMHDELD 715
Query: 540 EEKRRH----AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
KR I+ L + ++ L++++I EE + D L K ++++ K L
Sbjct: 716 SAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQE-------DLLRKRERELTALKGALK 768
Query: 596 EQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQ 654
E+ Q + +++ ++ EL+A + + A N+ ++ ++ T +V L+Q
Sbjct: 769 EEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQ 828
Query: 655 E 655
E
Sbjct: 829 E 829
>AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens
cDNA FLJ14957 fis, clone PLACE4000009, weakly similar to
MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 612
Score = 87.8 bits (208), Expect = 1e-16
Identities = 83/406 (20%), Positives = 194/406 (47%), Gaps = 21/406 (5%)
Query: 245 ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLS--VYILNDSSKQTS 302
E ++ E + + E+ ++ + ++ E KE V L + + QT+
Sbjct: 163 EDLKGDEAKAKETLKKYEGEIRQLEEALVHVRKEEKEAVSARRALENELEAAQGNLSQTT 222
Query: 303 IEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
E +QL+ ++ E E++ K ++ R+K +++ + L +++ K D+ + + +L+L
Sbjct: 223 QEQKQLSEKLKE-ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLEL 281
Query: 363 TEIQTHYDE--------VQRQLQ---VTLDQYGVAQRRIQSLTGEVEEIRGNYE----QA 407
Y E +QRQL+ + ++ + ++Q +EE +Y+ +A
Sbjct: 282 QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDEA 341
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERY 467
L ++ +EQ ++ + + + + + S ++E +++ + + +E + ER
Sbjct: 342 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLTERI 401
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
R + +++ L +E+ +E K SLE + K++ R+ +E + + ++ ++
Sbjct: 402 SRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQM 461
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
EARI ++E L+ E+R A R+ ER++KE+++Q +++ + L D ++ S ++
Sbjct: 462 EARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS---LTDQKDQLSLRL 518
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
KRQ+ E E + + ++ QRELE D + + L+ ++
Sbjct: 519 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMK 564
Score = 64.9 bits (151), Expect = 9e-10
Identities = 61/345 (17%), Positives = 159/345 (46%), Gaps = 14/345 (4%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARV-VEAETKLKSE 322
E+ + Y +L L+E+V++ +V +L +S+ + E +Q + V+ + +
Sbjct: 87 EMDKLKEQYDAELQALRESVEEATK-NVEVL--ASRSNTSEQDQAGTEMRVKLLQEENEK 143
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ ++L+ ++ +L+ ++ ++T+KK ++ +++ V+++ + +
Sbjct: 144 LQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHVRKEEKEAVSA 203
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ +++ G + + +Q + +Q E+ + NE+ +L + K+
Sbjct: 204 RRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKL 263
Query: 443 EQELAIVAADYDEITKELR-IADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
++E+A + T EL+ DE ++ + EL L E+ +EA K L
Sbjct: 264 QKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEK-----TLEAEKSRLTAM 318
Query: 502 VKNISVRLEEVEANAIVGGK-RIISK---LEARIKDMELELDEEKRRHAETIKILRKKER 557
+RL E E + ++K LE +KD+E EL+ + + +++++ E
Sbjct: 319 KMQDGMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMED 378
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
++ ++ ++ EE++ N LL + + ++ +++ + +L ++ Q
Sbjct: 379 KVSQLEMELEEERNNSDLLTERISRSREQMEQLRNELLQERAARQ 423
Score = 48.8 bits (111), Expect = 6e-05
Identities = 84/395 (21%), Positives = 177/395 (44%), Gaps = 31/395 (7%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+L + N N+ L +T+++ I+ ++S+ +++E++ ++ E + K + E+
Sbjct: 241 QLRRLKNEMENERWHLGKTIEKLQKEMADIV-EASRTSTLELQN---QLDEYKEKNRREL 296
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++++L+ + E E S A K +Q ++ +L + Q DE + Q+
Sbjct: 297 AEMQRQLKEKTLEAEKSRLTAMK----MQDGMRLMEEELRDYQRAQDEALTKRQLLEQTL 352
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ +++ + +++ R + + K S +E + EE + N ++ +S S+ ++
Sbjct: 353 KDLEYELEAKS-HLKDDRSRLVKQMEDKVSQLEMELEEER---NNSDLLTERISRSREQM 408
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
EQ L ++L +R +LK + HL E R K E + +E +
Sbjct: 409 EQ-LRNELLQERAARQDLECDKISLERQNKDLKSRIIHL-EGSYRSSK-EGLVVQMEARI 465
Query: 503 KNISVRLEEVE---ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ RLE E AN + +R LE ++K++ +++D+E H + +L
Sbjct: 466 AELEDRLESEERDRANLQLSNRR----LERKVKELVMQVDDE---HLSLTDQKDQLSLRL 518
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM--SQQSVTRVRRF-QRELE 616
K + Q EE ++ I L+ S +K +++ +G S + R+++ + L+
Sbjct: 519 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLD 578
Query: 617 AAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQV 650
+D D++ SL A TF STV SQ+
Sbjct: 579 DMDDDDDLSTDGGSLYEAPVSYTFSKDSTV-ASQI 612
Score = 37.9 bits (84), Expect = 0.11
Identities = 29/136 (21%), Positives = 67/136 (49%), Gaps = 11/136 (8%)
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQ---LKEVIIQCEEDQKNISLL----QDSL 580
+ I+D++ +L E H E R ++R+ L E ++Q ++D +++ + +D L
Sbjct: 7 QTEIRDLQDQLSE---MHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLL 63
Query: 581 EKTSQKVSIYKRQLAEQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTF 639
K ++++ K L E+ Q + +++ ++ EL+A + + A N+ ++ ++ T
Sbjct: 64 RKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTS 123
Query: 640 VTTSTVPGSQVYLVQE 655
+V L+QE
Sbjct: 124 EQDQAGTEMRVKLLQE 139
>S67247-1|AAB28952.1| 226|Homo sapiens smooth muscle myosin heavy
chain isoform SMemb protein.
Length = 226
Score = 87.4 bits (207), Expect = 1e-16
Identities = 45/179 (25%), Positives = 99/179 (55%)
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
++ + ++R+++ ++ L E+ K + ++ LE + K + +L+E+E
Sbjct: 1 DMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKS 60
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K IS LEA+I +E +L++E + A K++R+ E++LKE+ +Q E+++++ ++
Sbjct: 61 KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKE 120
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+EK + ++ KRQL E E + ++ R+ QREL+ A + + +S ++ + R
Sbjct: 121 QMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLR 179
Score = 42.3 bits (95), Expect = 0.005
Identities = 28/178 (15%), Positives = 83/178 (46%), Gaps = 2/178 (1%)
Query: 293 ILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSL-DVANKTNIDL 351
+LND ++T+++++ LNA + AE + +++L+ Q EL+ L ++
Sbjct: 4 LLNDRFRKTTLQVDTLNAELA-AERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKF 62
Query: 352 QKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVK 411
+ TI ++ +++ ++ ++ +++++ + +VE+ R + +Q
Sbjct: 63 KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM 122
Query: 412 RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR 469
+ ++ + ++ E ++S+ K+++EL + +++E+ R +R
Sbjct: 123 EKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 180
Score = 33.1 bits (72), Expect = 3.2
Identities = 23/113 (20%), Positives = 53/113 (46%), Gaps = 1/113 (0%)
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEA 529
++ ++ E L +E + + + E ++K I +++E+ +A K + K A
Sbjct: 69 LEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQY-KEQMEKANA 127
Query: 530 RIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
R+K ++ +L+E + RK +R+L + E + +S L++ L +
Sbjct: 128 RMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 180
>AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.
Length = 1302
Score = 87.0 bits (206), Expect = 2e-16
Identities = 83/406 (20%), Positives = 194/406 (47%), Gaps = 21/406 (5%)
Query: 245 ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYI--LNDSSKQTS 302
E ++ E + + E+ ++ + ++ E KE V L + + QT+
Sbjct: 853 EDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEGAQGNLSQTT 912
Query: 303 IEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
E +QL+ ++ E E++ K ++ R+K +++ + L +++ K D+ + + +L+L
Sbjct: 913 QEQKQLSEKLKE-ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLEL 971
Query: 363 TEIQTHYDE--------VQRQLQ---VTLDQYGVAQRRIQSLTGEVEEIRGNYE----QA 407
Y E +QRQL+ + ++ + ++Q +EE +Y+ +A
Sbjct: 972 QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDEA 1031
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERY 467
L ++ +EQ ++ + + + + + S ++E +++ + + +E + ER
Sbjct: 1032 LTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEAKVSQLEMELEEERNNSDLLSERI 1091
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
R + +++ L +E+ +E K SLE + K++ R+ +E + + ++ ++
Sbjct: 1092 SRSREQMEQLRNGLLQERAARQDLECGKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQM 1151
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
EARI ++E L+ E+R A R+ ER++KE+++Q +++ + L D ++ S ++
Sbjct: 1152 EARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS---LTDQKDQLSLRL 1208
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
KRQ+ E E + + ++ QRELE D + + L+ ++
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMK 1254
Score = 58.8 bits (136), Expect = 6e-08
Identities = 74/368 (20%), Positives = 163/368 (44%), Gaps = 35/368 (9%)
Query: 276 LNELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
+ EL + + DL + D ++ E+ L + E + E+ ++K++ +
Sbjct: 729 IEELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAE 788
Query: 334 ITELELSLDVANKTNIDL---QKTIKKQSLQLTEIQTHY-DEVQRQLQVTLDQYGVAQRR 389
+ L S++ A K N+++ + +Q TE++ E +LQ ++ +RR
Sbjct: 789 LQALRESVEEATK-NVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEEL---ERR 844
Query: 390 IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIV 449
+ L ++E+++G+ +A + ++YE ++ E V A+ E++ A+
Sbjct: 845 VAQLQRQIEDLKGDEAKA----KETLKKYEGEIRQLEEALV--------HARKEEKEAVS 892
Query: 450 AADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRL 509
A + EL A + E K E L EE E+ ++ +K +E E ++ +
Sbjct: 893 ARR--ALENELEGAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTI 950
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
E+++ I+ +++ +LDE K ++ L + +RQLKE ++ E+
Sbjct: 951 EKLQKEMA----DIVEASRTSTLELQNQLDEYKEKNRRE---LAEMQRQLKEKTLEAEKS 1003
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR--VRRFQRELEAAEDRADVAES 627
+ +QD + +++ Y+R A+ E ++++ + ++ + ELEA D
Sbjct: 1004 RLTAMKMQDGMRLMEEELRDYQR--AQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSR 1061
Query: 628 NLSLIRAK 635
+ + AK
Sbjct: 1062 LVKQMEAK 1069
Score = 50.8 bits (116), Expect = 2e-05
Identities = 84/395 (21%), Positives = 178/395 (45%), Gaps = 31/395 (7%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
+L + N N+ L +T+++ I+ ++S+ +++E++ ++ E + K + E+
Sbjct: 931 QLRRLKNEMENERWHLGKTIEKLQKEMADIV-EASRTSTLELQN---QLDEYKEKNRREL 986
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
++++L+ + E E S A K +Q ++ +L + Q DE + Q+
Sbjct: 987 AEMQRQLKEKTLEAEKSRLTAMK----MQDGMRLMEEELRDYQRAQDEALTKRQLLEQTL 1042
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ +++ + +++ R + + K S +E + EE + N +++ +S S+ ++
Sbjct: 1043 KDLEYELEAKS-HLKDDRSRLVKQMEAKVSQLEMELEEER---NNSDLLSERISRSREQM 1098
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
EQ L ++L +R +LK + HL E R K E + +E +
Sbjct: 1099 EQ-LRNGLLQERAARQDLECGKISLERQNKDLKSRIIHL-EGSYRSSK-EGLVVQMEARI 1155
Query: 503 KNISVRLEEVE---ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ RLE E AN + +R LE ++K++ +++D+E H + +L
Sbjct: 1156 AELEDRLESEERDRANLQLSNRR----LERKVKELVMQVDDE---HLSLTDQKDQLSLRL 1208
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM--SQQSVTRVRRF-QRELE 616
K + Q EE ++ I L+ S +K +++ +G S + R+++ + L+
Sbjct: 1209 KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLD 1268
Query: 617 AAEDRADVAESNLSLIRAK-HRTFVTTSTVPGSQV 650
+D D++ SL A TF STV SQ+
Sbjct: 1269 DMDDDDDLSTDGGSLYEAPVSYTFSKDSTV-ASQI 1302
Score = 49.2 bits (112), Expect = 5e-05
Identities = 75/384 (19%), Positives = 163/384 (42%), Gaps = 31/384 (8%)
Query: 248 RVRETSPTTCVVRINTE-LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
R TSP + +I+ + P+ N+ + +K +L+ +++KQ I
Sbjct: 509 RAAATSPDSGAKKISVKTFPSASNTQATP-----DLLKGQQELTQQTNEETAKQ--ILYN 561
Query: 307 QLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQ 366
L + + K +V + +K+Q + S N + +K Q +++
Sbjct: 562 YLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQ-GNNQACNSTSEVKDLLEQKSKLT 620
Query: 367 THYDEVQRQLQVTL-DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRV 425
E+QRQLQ+ + +Q + + R + + +EE+R + + + +++Q+ EES+ +
Sbjct: 621 IEVAELQRQLQLEVKNQQNIKEER-ERMRANLEELRSQHNEKVEENSTLQQRLEESEGEL 679
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
+ + + + + E+ + E+ EL A R + L +E L + +
Sbjct: 680 RKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGAL---IEELLQAK 736
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
+ + + K E + +R E E A+ G L+ + + E+D+ K ++
Sbjct: 737 QDLQDLLIAK-----EGREDLLRKRERELTALKGA------LKEEVSSHDQEMDKLKEQY 785
Query: 546 AETIKILRKK-ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
++ LR+ E K V + + N S + T +V + + + + +G S++
Sbjct: 786 DAELQALRESVEEATKNVEVLA--SRSNTS--EQDQAGTEMRVKLLQEENEKLQGRSEEL 841
Query: 605 VTRVRRFQRELEAAE-DRADVAES 627
RV + QR++E + D A E+
Sbjct: 842 ERRVAQLQRQIEDLKGDEAKAKET 865
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/241 (19%), Positives = 111/241 (46%), Gaps = 22/241 (9%)
Query: 421 SQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEH 480
S + V +L L+ A+++++L + + I +E + ++++ VE
Sbjct: 605 STSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEE 664
Query: 481 LHEEQERIVKIEA-VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELD 539
Q+R+ + E ++K+LE E+ + + E+ + I L+ ++ +M ELD
Sbjct: 665 NSTLQQRLEESEGELRKNLE-ELFQVKMEREQHQTE--------IRDLQDQLSEMHDELD 715
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLL----QDSLEKTSQKVSIYKRQLA 595
KR +++ L E ++Q ++D +++ + +D L K ++++ K L
Sbjct: 716 SAKRSED-------REKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGALK 768
Query: 596 EQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQ 654
E+ Q + +++ ++ EL+A + + A N+ ++ ++ T +V L+Q
Sbjct: 769 EEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQ 828
Query: 655 E 655
E
Sbjct: 829 E 829
>U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein.
Length = 2363
Score = 85.4 bits (202), Expect = 6e-16
Identities = 106/513 (20%), Positives = 229/513 (44%), Gaps = 47/513 (9%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
KR + ++ ++ Y +E+ E QK K + I T+ ++ R NE++ +
Sbjct: 723 KRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQII-NTMTQDLRG--ANEKLAVAEI 779
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
+A ++ LS+ L++ A + + ++ + E S T R+++
Sbjct: 780 RAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSS 839
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYI---LNDSSKQTSIEIEQLNARVVEAETKLK 320
++ +++ + +L+ V+Q L+ + L D+ +Q E L+ E +
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETN-LHLNTKELLKNAQ 898
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
E+ +K+ L + + VA++++ Q+T K Q ++ D++ QL+ T
Sbjct: 899 KEIATLKRHLS------NMEVQVASQSS---QRTGKGQPSNKEDV----DDLVSQLRQTE 945
Query: 381 DQYGVAQRRIQSLTGEVEEIRG---NYEQALRVKRSVEQQYEES-QTRVNELTVINVNLS 436
+Q + R+++ T VE+ + + E++L ++ V ++ ++ + R+ E L
Sbjct: 946 EQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLE 1005
Query: 437 SSKAKIEQELAIVAAD----YDEITKELRIADERYQRVQTELKHTVEHL-----HEEQER 487
++E+E + D + + ++L + VQ E++ ++ +E+Q R
Sbjct: 1006 KKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQAR 1065
Query: 488 IVKIEAVKKSLEIEVK-NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
E K ++E + K + L + A+ K +SK+ + + +E + + +
Sbjct: 1066 RDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLL 1125
Query: 547 ETIKILRKKERQLKE----VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE------ 596
E ++ER LK+ + +CE+ +K LL D +EK S KV ++ +
Sbjct: 1126 ECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVS 1185
Query: 597 --QEGMSQQSVTRVRRF-QRELEAAEDRADVAE 626
+EG SQ+ + + RF +RE E AE R +VA+
Sbjct: 1186 LSEEGKSQEQILEILRFIRREKEIAETRFEVAQ 1218
Score = 58.8 bits (136), Expect = 6e-08
Identities = 83/422 (19%), Positives = 184/422 (43%), Gaps = 37/422 (8%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQT-----LLEESRRNVQNER 197
++R++ +E+EL + +N E Q A + + + +T ++E ++ + +
Sbjct: 1225 RQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKE 1284
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKA-LMESKAMNSCDSRVTESITETVRVRETSPTT 256
+ D Q + V + ++ A A L E M + ++ E + + R +
Sbjct: 1285 RLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVS 1344
Query: 257 CVVRINTE----LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARV 312
+TE L + + ++ +L E + + L I ++ T+ + L +
Sbjct: 1345 QQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGR---LKAEIARSNASLTNNQ--NLIQSL 1399
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
E K+++E I+K L +I +++ + KT ++K ++ Q E++ D+V
Sbjct: 1400 KEDLNKVRTEKETIQKDLDAKIIDIQEKV----KTITQVKKIGRRYKTQYEELKAQQDKV 1455
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE-------ESQTRV 425
++ + G Q + S+ E++E++ QA +S+E Q E E +T
Sbjct: 1456 ---METSAQSSGDHQEQHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEA 1511
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
L V L S +++ Q+L +++ +++ +E+ ++ K + HL
Sbjct: 1512 RNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAG-- 1569
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
VK + K++ E++ +N ++ ++ E + + + S+ E RI +E EL E + RH
Sbjct: 1570 ---VKDQLTKENEELKQRNGALDQQKDELDVRITALK--SQYEGRISRLERELREHQERH 1624
Query: 546 AE 547
E
Sbjct: 1625 LE 1626
Score = 52.0 bits (119), Expect = 7e-06
Identities = 93/512 (18%), Positives = 212/512 (41%), Gaps = 37/512 (7%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAI---AQTLLEESRRNVQNERMY 199
+K++ E+EKE + + E ++ K+ ++ Q L+ + + NE+
Sbjct: 1005 EKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQA 1064
Query: 200 KPDFQASRTLVNRDYTNLSKNVL-----AKALMESKAMNSCDSRVTESITETVRVRETSP 254
+ D Q + + ++ +AL +K S + V + + ET + E+
Sbjct: 1065 RRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQL 1124
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE----QLNA 310
C + + + ++ KQ L I S K + E LN
Sbjct: 1125 LECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNV 1184
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
+ E E K + ++ I + ++ + E +VA ++ ++ ++ +L E+Q +
Sbjct: 1185 SLSE-EGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLN 1243
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV 430
+ ++QVT + T + + + K +EQ ++ Q +V +L +
Sbjct: 1244 AEREKVQVTAKTM-AQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLEL 1302
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK--HTVEH---LHEEQ 485
+ L + A++ ++ ++ A+ + ++++ R Q + ++ K T E+ L E++
Sbjct: 1303 DILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKE 1362
Query: 486 ERIVKIEAVKKS---LEIEVKNISVRLEEVEANAIVGGKRIISKL----EARIKDME--- 535
+I+ + + L+ E+ + L N I K ++K+ E KD++
Sbjct: 1363 VHTKRIQQLTEEIGRLKAEIARSNASLTN-NQNLIQSLKEDLNKVRTEKETIQKDLDAKI 1421
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ-- 593
+++ E+ + + KI R+ + Q +E ++ ++D+ + Q S + Q VS+ + Q
Sbjct: 1422 IDIQEKVKTITQVKKIGRRYKTQYEE--LKAQQDKVMETSAQSSGDHQEQHVSVQEMQEL 1479
Query: 594 ---LAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L + E S+ ++V Q+ L E A
Sbjct: 1480 KETLNQAETKSKSLESQVENLQKTLSEKETEA 1511
Score = 49.2 bits (112), Expect = 5e-05
Identities = 58/324 (17%), Positives = 145/324 (44%), Gaps = 17/324 (5%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E L + E + L +E ++K+Q+ + ++ KT + + + + L E
Sbjct: 1228 VELLERELQELQDSLNAE----REKVQVTAKTMAQHEELMKKT--ETMNVVMETNKMLRE 1281
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+ ++ +Q+Q + + + +Q E+ E G + K+ +E+ + + R
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAE---KKLLEEDVKRWKAR 1338
Query: 425 VNELTVINVNLSSSK-AKIEQELAIVAADYDEITKEL-RIADE--RYQRVQTELKHTVEH 480
L + + + K+ E + ++T+E+ R+ E R T ++ ++
Sbjct: 1339 NQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQS 1398
Query: 481 LHEEQERI-VKIEAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELE 537
L E+ ++ + E ++K L+ ++ +I +++ + +G K +L+A+ +D +E
Sbjct: 1399 LKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQ-QDKVME 1457
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
+ + + ++ ++LKE + Q E K++ ++L+KT + R L EQ
Sbjct: 1458 TSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQ 1517
Query: 598 EGMSQQSVTRVRRFQRELEAAEDR 621
Q ++R+R+ ++ E++
Sbjct: 1518 TVQLQSELSRLRQDLQDRTTQEEQ 1541
Score = 47.6 bits (108), Expect = 1e-04
Identities = 96/508 (18%), Positives = 212/508 (41%), Gaps = 49/508 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSEL--RQKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
+K + I K LD KEV + + RQ+ R + A A LE++ + +Q
Sbjct: 412 EKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQ----- 466
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
R + D N +VL + +++ M +++ I + E + V+
Sbjct: 467 -------RLQEDTDKANKQSSVLER---DNRRMEIQVKDLSQQIRVLLMELEEARGNHVI 516
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-ARVVEAETK 318
R + E+ + D S +++ + + + + ++ L +++ + + +L R E +
Sbjct: 517 R-DEEVSSADISSSSEV--ISQHLVSYRNIEE--LQQQNQRLLVALRELGETREREEQET 571
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
S++T ++ KL+ +TELE L + + + L +I +Q + + V L
Sbjct: 572 TSSKITELQLKLESALTELE-QLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHA 630
Query: 379 -TLDQYGVAQRRIQSLTGEVEEIRG-----NYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+LD +A + T + +A+ K +++Q E + E
Sbjct: 631 SSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENE 690
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL---KHTVEHLHEEQERIV 489
+ K+++++ + + +I+ +L A +RY+ +Q + + + LHE +++
Sbjct: 691 KIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT 750
Query: 490 ----KIEAVKKSLEIEVK--NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
K E + ++ +++ N + + E+ A + K ++ E R+ L E+R
Sbjct: 751 ATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQR 810
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+L + ++ ++ + E + K L +EK ++S K++L E +Q
Sbjct: 811 GQ----NLLLTNLQTIQGILERSETETK--QRLSSQIEKLEHEISHLKKKL---ENEVEQ 861
Query: 604 SVTRVRRFQRELEAAEDRADVAESNLSL 631
T R +L + + D E+NL L
Sbjct: 862 RHTLTRNLDVQLLDTKRQLD-TETNLHL 888
Score = 47.2 bits (107), Expect = 2e-04
Identities = 82/399 (20%), Positives = 175/399 (43%), Gaps = 37/399 (9%)
Query: 260 RINTELPAIDNSYLNQLNE-LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
R++ EL + + +LNE LKE+ +L + + D + + + ++ R+ + +
Sbjct: 133 RLSQELEYLTED-VKRLNEKLKESNTTKGELQLKL--DELQASDVSVKYREKRLEQEKEL 189
Query: 319 LKSEVTRIKKKLQIQITEL-ELSLDVAN-----KTNIDLQKT-IKKQSLQLTEIQTHYDE 371
L S+ T + +L+ + EL L + N K N++ +K + + Q+ ++T +
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEH 249
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+Q+ ++ L + A+ + S+ E+ +++ + ++S+ + NELT
Sbjct: 250 LQKHVEDLLTKLKEAKEQQASME---EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRA 306
Query: 432 NVNL-------SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
L + I+ L V D++ KE+ E+ R++ EL++ + L
Sbjct: 307 VEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEML---EKIGRLEKELENANDLLSAT 363
Query: 485 QERIV-----KIEAVKKSLEIEVKNISVRLEEVEA-NAIVG--GKRIISKLE-ARIKDME 535
+ + ++ A+ + K + ++ E NA V + ++ KLE RI
Sbjct: 364 KRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYL 423
Query: 536 LELDEEKRRHAETIKILRKK-ERQLKEVI---IQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E+ +E A +K R++ ER K V ++ E+ K I LQ+ +K +++ S+ +
Sbjct: 424 DEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLE 483
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLS 630
R E + ++R ELE A + + +S
Sbjct: 484 RDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVS 522
Score = 39.5 bits (88), Expect = 0.037
Identities = 50/240 (20%), Positives = 110/240 (45%), Gaps = 15/240 (6%)
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E + Y E++++L + ++ R QSL E+E++ N +AL K ++ E +Q
Sbjct: 49 ESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKL-NNQLKALTEK---NKELEIAQD 104
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
R I + +K ++E E + + +++EL E +R+ +LK + E
Sbjct: 105 R---NIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGE 161
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
Q ++ +++A ++ VK RLE+ + + ++L+ + ++ L L EK
Sbjct: 162 LQLKLDELQA----SDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDEL-LALGREKG 216
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
E +++ E + KE + + EE + + L+K + + ++ EQ+ ++
Sbjct: 217 N--EILELKCNLENK-KEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE 273
Score = 34.7 bits (76), Expect = 1.1
Identities = 56/326 (17%), Positives = 133/326 (40%), Gaps = 26/326 (7%)
Query: 273 LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE-TKLKSEVTRIKKKLQ 331
+N+ E + + + L+ + + K +EI Q ++++ T+ K E+ K+ L
Sbjct: 69 VNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLI 128
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
L L+ + L + +K+ + E+Q DE+Q V++ + R +
Sbjct: 129 RTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS-DVSV------KYREK 181
Query: 392 SLTGEVEEIRG-NYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK---AKIEQELA 447
L E E + N +K ++ + + NE+ + NL + K +++E+++
Sbjct: 182 RLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMN 241
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ + + K + + + + + E H E +K+ + KS +
Sbjct: 242 GLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADD------ 295
Query: 508 RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCE 567
E ++N + R + +L +K+ + K +++ + K++ KE++ +
Sbjct: 296 --SEAKSNELT---RAVEELHKLLKEAG---EANKAIQDHLLEVEQSKDQMEKEMLEKIG 347
Query: 568 EDQKNISLLQDSLEKTSQKVSIYKRQ 593
+K + D L T +K +I +
Sbjct: 348 RLEKELENANDLLSATKRKGAILSEE 373
Score = 32.3 bits (70), Expect = 5.6
Identities = 39/159 (24%), Positives = 76/159 (47%), Gaps = 21/159 (13%)
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
LE E N + K + +KLE + D + E+D K RH E K+ + E+Q E+
Sbjct: 9 LERTELNKLP--KSVQNKLEKFLADQQSEIDGLKGRH-EKFKV--ESEQQYFEI------ 57
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESN 628
+K +S Q+ L +++ + +L E ++ Q + + +ELE A+DR +S
Sbjct: 58 -EKRLSHSQERLVNETRECQSLRLEL---EKLNNQ-LKALTEKNKELEIAQDRNIAIQSQ 112
Query: 629 LSL----IRAKHRTFVTTSTVPGSQV-YLVQESRALSSE 662
+ + A+ R + T+ ++ YL ++ + L+ +
Sbjct: 113 FTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEK 151
>AL132825-2|CAI43041.1| 144|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 144
Score = 85.0 bits (201), Expect = 8e-16
Identities = 47/129 (36%), Positives = 77/129 (59%), Gaps = 22/129 (17%)
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
++++E ELD E+++HAE +K +RK ER++KE+ Q EED+KN++ +QD ++K KV Y
Sbjct: 1 VRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSY 60
Query: 591 KRQLAE----------------------QEGMSQQSVTRVRRFQRELEAAEDRADVAESN 628
KRQ E QE + ++ + R+ Q EL+ AE+RAD+AE+
Sbjct: 61 KRQFEEAVSALGPGHLDRAPQLCPRVCGQEQQANTNLAKYRKAQHELDDAEERADMAETQ 120
Query: 629 LSLIRAKHR 637
+ +RA+ R
Sbjct: 121 ANKLRARTR 129
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 84.6 bits (200), Expect = 1e-15
Identities = 118/591 (19%), Positives = 254/591 (42%), Gaps = 49/591 (8%)
Query: 62 KYRFNKPIRAYSEEDLTRISHDIAEQAK--RDLNTFTVGKRSPFSVIATAAAANVTKHVG 119
KY + +R +E+ +TR++ ++ ++A +DL T + +R +A V
Sbjct: 178 KYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELL-QRPGIEDVAVLKKELVQVQTL 236
Query: 120 VESVTVXXXXXXXXXXXXXXXXQKKRMQEIEKELDLYEKEVNLGSELRQKAAMY--RGKS 177
++++T+ Q + E + E+ G Q+ A+Y +
Sbjct: 237 MDNMTLERERESEKLKDECKKLQSQYASS-EATISQLRSELAKGP---QEVAVYVQELQK 292
Query: 178 AKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDS 237
K+ L ++++ +N + D+ N + + KN+ A + S
Sbjct: 293 LKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVS-KKNIQATLHQKDLDCQQLQS 351
Query: 238 RVTESITETVRVR-ETSPT-TCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILN 295
R++ S T R+ E S ++ EL ++ Y + E K+ +Q ++ + L
Sbjct: 352 RLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGL- 410
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
Q EI QL+++++E E +L R+K++ Q+ +L +D + DLQ +
Sbjct: 411 ----QLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKL---MDKEQQV-ADLQLKL 462
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ QL E T+ E+Q QL T Q+ Q QS T ++ E + + EQ LR +
Sbjct: 463 SRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKD 522
Query: 416 QQYEESQTRVNE----LTVINVNLSSSKAKI---EQELAI----------VAADYDEITK 458
Q+ + + + + ++++ AKI E E A+ + ++T+
Sbjct: 523 QKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTE 582
Query: 459 ELRIADERYQRVQTELKHTVE----HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
+L+ E +++ Q L V+ HL Q+R++ +E L ++ ++ +++
Sbjct: 583 KLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDI 642
Query: 515 NAIVGGKRIISKLEARI---KDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+ ++S A+ D++ LD + + + L K QL +V + ++ Q+
Sbjct: 643 QIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQE 702
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
+ S L+ L++ +K +++ E EG + ++ E++A++++A
Sbjct: 703 HCSQLESHLKEYKEKYLSLEQKTEELEG----QIKKLEADSLEVKASKEQA 749
Score = 64.5 bits (150), Expect = 1e-09
Identities = 92/477 (19%), Positives = 201/477 (42%), Gaps = 20/477 (4%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
K +++ E L +KE + + + + K T L+ + + +
Sbjct: 438 KEQRQLSSE-KLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQAL 496
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
Q S T R+ N + VL + + + + + ++ + +S E + + E +I
Sbjct: 497 QQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKS-KENISLLEKEREDLYAKI-- 553
Query: 264 ELPAIDNSYLNQLNELKETVK-QFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+ + + LNQL E T++ Q L+ + N S + E L+ +V E + L++
Sbjct: 554 QAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQ-ENLHDQVQEQKAHLRAA 612
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
R+ L+ + EL L+ + + L IK ++ L + + LQ LD
Sbjct: 613 QDRVLS-LETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLD- 670
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
AQ +Q E+ +I +Q + ++ + ++ + E ++L ++
Sbjct: 671 --TAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEEL 728
Query: 443 EQELAIVAADYDEI--TKELRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
E ++ + AD E+ +KE + D + QR + T+L+ L ++ E +I + S
Sbjct: 729 EGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVS---STR 785
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
++++ S LE ++ K+ K + +D E E K +H E ++ +L
Sbjct: 786 LDLQKKSEALESIKQKLT---KQEEEKQILK-QDFETLSQETKIQHEELNNRIQTTVTEL 841
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
++V ++ E +S ++D L K S + K + ++ + ++ + + +EL+
Sbjct: 842 QKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELK 898
Score = 60.5 bits (140), Expect = 2e-08
Identities = 86/504 (17%), Positives = 221/504 (43%), Gaps = 23/504 (4%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIA-QTLLEESRRNVQNERMYK 200
+K +E++KEL+ Y+ L + + + SA+ + + LEE++ N + K
Sbjct: 102 EKWYSEELKKELEKYQ---GLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMK 158
Query: 201 PDFQASRTLVNRDYTNL-SKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
F+ + + ++ SK ++L E+ +R+TE + + V + T +
Sbjct: 159 DLFEQKAAQLATEIADIKSKYDEERSLREAAEQKV--TRLTEELNKEATVIQDLKTELLQ 216
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
R E A+ L Q+ L + + + L D K+ + A + + ++L
Sbjct: 217 RPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSEL 276
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV---QRQL 376
+ +Q ++ +L+ S++ + N L + + K+ T+++ ++E ++ +
Sbjct: 277 AKGPQEVAVYVQ-ELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNI 335
Query: 377 QVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
Q TL Q + +++QS E I + + ++++ E +T+ L
Sbjct: 336 QATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEF 395
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKEL----RIADERYQRVQTELKHTVEHLHEEQERI 488
L + + EQ + ++ +++ +L R E + R++ + + + E L ++++++
Sbjct: 396 KQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQV 455
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
++ LE ++K E++ + + K+ + +A + +L E + +
Sbjct: 456 ADLQLKLSRLEEQLKEKVTNSTELQ-HQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQV 514
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT-- 606
++ + K+++++ + ++ ++NISLL+ E K+ + + A + +++ T
Sbjct: 515 LRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQ 574
Query: 607 -RVRRFQRELEAAEDRADVAESNL 629
+V + +L+ + A+ NL
Sbjct: 575 EQVTQLTEKLKNQSESHKQAQENL 598
Score = 55.6 bits (128), Expect = 5e-07
Identities = 70/362 (19%), Positives = 161/362 (44%), Gaps = 16/362 (4%)
Query: 280 KETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELEL 339
+ET Q ++L+ I ++ +++E+ A + E T +K +++++ L+ +E E
Sbjct: 821 QETKIQHEELNNRIQTTVTELQKVKMEK-EALMTELST-VKDKLSKVSDSLKNSKSEFEK 878
Query: 340 SLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEE 399
+DL+KT K+ QL + + Q++L+ +L++ A +++ E+
Sbjct: 879 ENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKL---ELNS 935
Query: 400 IRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE---- 455
++ QA + E++ ++ Q +NEL + ++ EL I E
Sbjct: 936 MQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENK 995
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN 515
+ ++L A + + ++ + + QE ++++ E E+ L+ VE
Sbjct: 996 LQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEK 1055
Query: 516 AIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL 575
+ + +IS +I + + E K A + KKE+QL+E ++ QK SL
Sbjct: 1056 LSLAQEDLISN-RNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSL 1114
Query: 576 LQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR--FQRELEAAEDRADVAESNLSLIR 633
+ L K++ ++ E + ++ +T++ +LE+ ++ ++ ++ LI+
Sbjct: 1115 KEKELVNEKSKLA----EIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQ 1170
Query: 634 AK 635
K
Sbjct: 1171 QK 1172
Score = 54.8 bits (126), Expect = 9e-07
Identities = 83/394 (21%), Positives = 171/394 (43%), Gaps = 37/394 (9%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLNARV----- 312
++ EL ++ + N LK+ K+ L I L SS+Q +IE L +
Sbjct: 928 QLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVL 987
Query: 313 --VEAETKLKSEVTRIKKKLQIQ---ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQT 367
E E KL+ ++T+ ++L + I+ L+ + + + +T LQ + +L +
Sbjct: 988 QKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQ 1047
Query: 368 HYDEVQRQLQVTLDQYGVAQRRI---QSLTGEVEEIRGNYEQ-ALRVKRSVEQQYEESQT 423
V+ +L + + + +I L E++ + EQ + + ++ ++++ + Q
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQD 1107
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITK---ELRIADERYQRVQTELKHTVEH 480
E ++ L + K+K+ + I EITK EL+ + T LK +
Sbjct: 1108 IQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQL 1167
Query: 481 LHEEQERIV-KIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII---SKLEARIKDMEL 536
L +++ + K +++K ++E E +N + ++V+ K I +KL + IK+ E+
Sbjct: 1168 LIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEV 1227
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS----------LEKTSQK 586
+ + + A+ + L V + + Q+ +S L+ LE T Q
Sbjct: 1228 GMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQN 1287
Query: 587 VSIYKRQLAEQ----EGMSQQSVTRVRRFQRELE 616
+R L E+ EG ++ T+V QR+L+
Sbjct: 1288 NQDERRALLERCLKGEGEIEKLQTKVLELQRKLD 1321
Score = 47.2 bits (107), Expect = 2e-04
Identities = 46/224 (20%), Positives = 106/224 (47%), Gaps = 16/224 (7%)
Query: 293 ILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQ 352
++N+ SK EIE++ R + TKL E+ K + +IT L+ + + + ++LQ
Sbjct: 1119 LVNEKSKLA--EIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQ 1176
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K SL+ ++ +R Q+ DQ ++ + L E E ++ K
Sbjct: 1177 G--KADSLKAA-----VEQEKRNQQILKDQ---VKKEEEELKKEFIEKEAKLHSEIKEKE 1226
Query: 413 SVEQQYEESQTRVN-ELTVINVNLSSSKAK---IEQELAIVAADYDEITKELRIADERYQ 468
+++EE++ ++ ++T +N NL + K + ++ ++ + D++ E+ + + Q
Sbjct: 1227 VGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQ 1286
Query: 469 RVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
Q E + +E + + I K++ L+ ++ N + ++E+
Sbjct: 1287 NNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQEL 1330
Score = 43.6 bits (98), Expect = 0.002
Identities = 53/234 (22%), Positives = 113/234 (48%), Gaps = 21/234 (8%)
Query: 412 RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQ 471
+S+EQQ EE+QT + + A++ E+A + + YDE A+++ R+
Sbjct: 138 QSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLT 197
Query: 472 TELKH---TVEHLHEE---QERIVKIEAVKKSL-EIEVKNISVRLE-EVEANAIVGG-KR 522
EL ++ L E + I + +KK L +++ ++ LE E E+ + K+
Sbjct: 198 EELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKK 257
Query: 523 IISKL---EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS 579
+ S+ EA I + EL + + A ++ L+K + + E+ QKN +L ++
Sbjct: 258 LQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNEL------TQKNQTLTENL 311
Query: 580 LEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
L+K + ++ +E +S++++ + Q++L+ + ++ ++ S SL R
Sbjct: 312 LKKEQDYTKLEEKH--NEESVSKKNI-QATLHQKDLDCQQLQSRLSASETSLHR 362
>X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein.
Length = 2349
Score = 84.6 bits (200), Expect = 1e-15
Identities = 106/513 (20%), Positives = 229/513 (44%), Gaps = 47/513 (9%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
KR + ++ ++ Y +E+ E QK K + I T+ ++ R NE++ +
Sbjct: 723 KRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQII-NTMTQDLRG--ANEKLAVAEV 779
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
+A ++ LS+ L++ A + + ++ + E S T R+++
Sbjct: 780 RAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSS 839
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYI---LNDSSKQTSIEIEQLNARVVEAETKLK 320
++ +++ + +L+ V+Q L+ + L D+ +Q E L+ E +
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETN-LHLNTKELLKNAQ 898
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
E+ +K+ L + + VA++++ Q+T K Q ++ D++ QL+ T
Sbjct: 899 KEIATLKQHLS------NMEVQVASQSS---QRTGKGQPSNKEDV----DDLVSQLRQTE 945
Query: 381 DQYGVAQRRIQSLTGEVEEIRG---NYEQALRVKRSVEQQYEES-QTRVNELTVINVNLS 436
+Q + R+++ T VE+ + + E++L ++ V ++ ++ + R+ E L
Sbjct: 946 EQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLE 1005
Query: 437 SSKAKIEQELAIVAAD----YDEITKELRIADERYQRVQTELKHTVEHL-----HEEQER 487
++E+E + D + + ++L + VQ E++ ++ +E+Q R
Sbjct: 1006 KKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQAR 1065
Query: 488 IVKIEAVKKSLEIEVK-NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
E K ++E + K + L + A+ K +SK+ + + +E + + +
Sbjct: 1066 RDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLL 1125
Query: 547 ETIKILRKKERQLKE----VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE------ 596
E ++ER LK+ + +CE+ +K LL D +EK S KV ++ +
Sbjct: 1126 ECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVS 1185
Query: 597 --QEGMSQQSVTRVRRF-QRELEAAEDRADVAE 626
+EG SQ+ + + RF +RE E AE R +VA+
Sbjct: 1186 LSEEGKSQEQILEILRFIRREKEIAETRFEVAQ 1218
Score = 60.1 bits (139), Expect = 2e-08
Identities = 84/422 (19%), Positives = 184/422 (43%), Gaps = 37/422 (8%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQT-----LLEESRRNVQNER 197
++R++ +E+EL E +N E Q A + + + +T ++E ++ + +
Sbjct: 1225 RQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKE 1284
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKA-LMESKAMNSCDSRVTESITETVRVRETSPTT 256
+ D Q + V + ++ A A L E M + ++ E + + R +
Sbjct: 1285 RLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVS 1344
Query: 257 CVVRINTE----LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARV 312
+TE L + + ++ +L E + + L I ++ T+ + L +
Sbjct: 1345 QQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGR---LKAEIARSNASLTNNQ--NLIQSL 1399
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
E K+++E I+K L +I +++ + KT ++K ++ Q E++ D+V
Sbjct: 1400 KEDLNKVRTEKETIQKDLDAKIIDIQEKV----KTITQVKKIGRRYKTQYEELKAQQDKV 1455
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE-------ESQTRV 425
++ + G Q + S+ E++E++ QA +S+E Q E E +T
Sbjct: 1456 ---METSAQSSGDHQEQHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEA 1511
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
L V L S +++ Q+L +++ +++ +E+ ++ K + HL
Sbjct: 1512 RNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAG-- 1569
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
VK + K++ E++ +N ++ ++ E + + + S+ E RI +E EL E + RH
Sbjct: 1570 ---VKDQLTKENEELKQRNGALDQQKDELDVRITALK--SQYEGRISRLERELREHQERH 1624
Query: 546 AE 547
E
Sbjct: 1625 LE 1626
Score = 50.4 bits (115), Expect = 2e-05
Identities = 59/324 (18%), Positives = 145/324 (44%), Gaps = 17/324 (5%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E L + E E L +E ++K+Q+ + ++ KT + + + + L E
Sbjct: 1228 VELLERELQELEDSLNAE----REKVQVTAKTMAQHEELMKKT--ETMNVVMETNKMLRE 1281
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+ ++ +Q+Q + + + +Q E+ E G + K+ +E+ + + R
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAE---KKLLEEDVKRWKAR 1338
Query: 425 VNELTVINVNLSSSK-AKIEQELAIVAADYDEITKEL-RIADE--RYQRVQTELKHTVEH 480
L + + + K+ E + ++T+E+ R+ E R T ++ ++
Sbjct: 1339 NQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQS 1398
Query: 481 LHEEQERI-VKIEAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELE 537
L E+ ++ + E ++K L+ ++ +I +++ + +G K +L+A+ +D +E
Sbjct: 1399 LKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQ-QDKVME 1457
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
+ + + ++ ++LKE + Q E K++ ++L+KT + R L EQ
Sbjct: 1458 TSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQ 1517
Query: 598 EGMSQQSVTRVRRFQRELEAAEDR 621
Q ++R+R+ ++ E++
Sbjct: 1518 TVQLQSELSRLRQDLQDRTTQEEQ 1541
Score = 48.0 bits (109), Expect = 1e-04
Identities = 97/508 (19%), Positives = 212/508 (41%), Gaps = 49/508 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSEL--RQKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
+K + I K LD KEV + + RQ+ R + A A LE++ + +Q
Sbjct: 412 EKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQ----- 466
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
R + D N +VL + +++ M +++ I + E + V+
Sbjct: 467 -------RLQEDTDKANKQSSVLER---DNRRMEIQVKDLSQQIRVLLMELEEARGNHVI 516
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-ARVVEAETK 318
R + E+ + D S +++ + + + + ++ L +++ + + +L R E +
Sbjct: 517 R-DEEVSSADISSSSEV--ISQHLVSYRNIEE--LQQQNQRLLVALRELGETREREEQET 571
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
S++T ++ KL+ +TELE L + + + L +I +Q + + V L
Sbjct: 572 TSSKITELQLKLESALTELE-QLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHA 630
Query: 379 -TLDQYGVAQRRIQSLTGEVEEIRG-----NYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+LD +A + T + +A+ K +++Q E + E
Sbjct: 631 SSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENE 690
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL---KHTVEHLHEEQERIV 489
+ K+++++ + + +I+ +L A +RY+ +Q + + + LHE +++
Sbjct: 691 KIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT 750
Query: 490 ----KIEAVKKSLEIEVK--NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
K E + ++ +++ N + + EV A + K ++ E R+ L E+R
Sbjct: 751 ATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQR 810
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+L + ++ ++ + E + K L +EK ++S K++L E +Q
Sbjct: 811 GQ----NLLLTNLQTIQGILERSETETK--QRLSSQIEKLEHEISHLKKKL---ENEVEQ 861
Query: 604 SVTRVRRFQRELEAAEDRADVAESNLSL 631
T R +L + + D E+NL L
Sbjct: 862 RHTLTRNLDVQLLDTKRQLD-TETNLHL 888
Score = 47.2 bits (107), Expect = 2e-04
Identities = 82/399 (20%), Positives = 175/399 (43%), Gaps = 37/399 (9%)
Query: 260 RINTELPAIDNSYLNQLNE-LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
R++ EL + + +LNE LKE+ +L + + D + + + ++ R+ + +
Sbjct: 133 RLSQELEYLTED-VKRLNEKLKESNTTKGELQLKL--DELQASDVSVKYREKRLEQEKEL 189
Query: 319 LKSEVTRIKKKLQIQITEL-ELSLDVAN-----KTNIDLQKT-IKKQSLQLTEIQTHYDE 371
L S+ T + +L+ + EL L + N K N++ +K + + Q+ ++T +
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEH 249
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+Q+ ++ L + A+ + S+ E+ +++ + ++S+ + NELT
Sbjct: 250 LQKHVEDLLTKLKEAKEQQASME---EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRA 306
Query: 432 NVNL-------SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
L + I+ L V D++ KE+ E+ R++ EL++ + L
Sbjct: 307 VEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEML---EKIGRLEKELENANDLLSAT 363
Query: 485 QERIV-----KIEAVKKSLEIEVKNISVRLEEVEA-NAIVG--GKRIISKLE-ARIKDME 535
+ + ++ A+ + K + ++ E NA V + ++ KLE RI
Sbjct: 364 KRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYL 423
Query: 536 LELDEEKRRHAETIKILRKK-ERQLKEVI---IQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E+ +E A +K R++ ER K V ++ E+ K I LQ+ +K +++ S+ +
Sbjct: 424 DEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLE 483
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLS 630
R E + ++R ELE A + + +S
Sbjct: 484 RDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVS 522
Score = 39.5 bits (88), Expect = 0.037
Identities = 50/240 (20%), Positives = 110/240 (45%), Gaps = 15/240 (6%)
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E + Y E++++L + ++ R QSL E+E++ N +AL K ++ E +Q
Sbjct: 49 ESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKL-NNQLKALTEK---NKELEIAQD 104
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
R I + +K ++E E + + +++EL E +R+ +LK + E
Sbjct: 105 R---NIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGE 161
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
Q ++ +++A ++ VK RLE+ + + ++L+ + ++ L L EK
Sbjct: 162 LQLKLDELQA----SDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDEL-LALGREKG 216
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
E +++ E + KE + + EE + + L+K + + ++ EQ+ ++
Sbjct: 217 N--EILELKCNLENK-KEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE 273
Score = 38.7 bits (86), Expect = 0.065
Identities = 90/553 (16%), Positives = 222/553 (40%), Gaps = 29/553 (5%)
Query: 89 KRDLNTFTVGKRSPFSVIATAAAANVTKHVGVESVTVXXXXXXXXXXXXXXXXQKKRMQE 148
KR L+T T + ++ A T + ++ V K+ + +
Sbjct: 877 KRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDD 936
Query: 149 IEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRT 208
+ +L E++VN E R K + + +A+ +L E + Q + + +
Sbjct: 937 LVSQLRQTEEQVNDLKE-RLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLK 995
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAI 268
T L K ++ + E + + R ES+ + + + + ++ + L
Sbjct: 996 ESAEFQTQLEKKLM-EVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRA 1054
Query: 269 DNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI---EIEQLNA--RVVEAETKLKSEV 323
+ N+ ++ +Q ++V N ++ + ++E L A V ++ +
Sbjct: 1055 STALSNEQQARRDCQEQAK-IAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHL 1113
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
+K + Q+ E + S + + L+ + K + +++ + Q++ D+
Sbjct: 1114 EETTQKAESQLLECKASWEERERM---LKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKV 1170
Query: 384 GVAQRR-IQS-LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
+ + +Q L + E + EQ L + R + ++ E ++TR V ++
Sbjct: 1171 VASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVEL 1230
Query: 442 IEQELA----IVAADYDEI---TKELRIADERYQRVQT--ELKHTVEHLHEEQERIVKIE 492
+E+EL + A+ +++ K + +E ++ +T + T + L EE+ER +E
Sbjct: 1231 LERELQELEDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKER---LE 1287
Query: 493 AVKKSLEIEVKNISVRLEEV-EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
+ ++ +V+ + + + + EANA + K L+A K +E ++ K R+ +
Sbjct: 1288 QDLQQMQAKVRKLELDILPLQEANAELSEKS--GMLQAEKKLLEEDVKRWKARNQHLVSQ 1345
Query: 552 LRKKE-RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
+ + + ++++ + E K I L + + + +++ L + + Q + +
Sbjct: 1346 QKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNK 1405
Query: 611 FQRELEAAEDRAD 623
+ E E + D
Sbjct: 1406 VRTEKETIQKDLD 1418
Score = 34.7 bits (76), Expect = 1.1
Identities = 56/326 (17%), Positives = 133/326 (40%), Gaps = 26/326 (7%)
Query: 273 LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE-TKLKSEVTRIKKKLQ 331
+N+ E + + + L+ + + K +EI Q ++++ T+ K E+ K+ L
Sbjct: 69 VNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLI 128
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
L L+ + L + +K+ + E+Q DE+Q V++ + R +
Sbjct: 129 RTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS-DVSV------KYREK 181
Query: 392 SLTGEVEEIRG-NYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK---AKIEQELA 447
L E E + N +K ++ + + NE+ + NL + K +++E+++
Sbjct: 182 RLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMN 241
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ + + K + + + + + E H E +K+ + KS +
Sbjct: 242 GLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADD------ 295
Query: 508 RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCE 567
E ++N + R + +L +K+ + K +++ + K++ KE++ +
Sbjct: 296 --SEAKSNELT---RAVEELHKLLKEAG---EANKAIQDHLLEVEQSKDQMEKEMLEKIG 347
Query: 568 EDQKNISLLQDSLEKTSQKVSIYKRQ 593
+K + D L T +K +I +
Sbjct: 348 RLEKELENANDLLSATKRKGAILSEE 373
Score = 32.3 bits (70), Expect = 5.6
Identities = 39/159 (24%), Positives = 76/159 (47%), Gaps = 21/159 (13%)
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
LE E N + K + +KLE + D + E+D K RH E K+ + E+Q E+
Sbjct: 9 LERTELNKLP--KSVQNKLEKFLADQQSEIDGLKGRH-EKFKV--ESEQQYFEI------ 57
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESN 628
+K +S Q+ L +++ + +L E ++ Q + + +ELE A+DR +S
Sbjct: 58 -EKRLSHSQERLVNETRECQSLRLEL---EKLNNQ-LKALTEKNKELEIAQDRNIAIQSQ 112
Query: 629 LSL----IRAKHRTFVTTSTVPGSQV-YLVQESRALSSE 662
+ + A+ R + T+ ++ YL ++ + L+ +
Sbjct: 113 FTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEK 151
>AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 84.6 bits (200), Expect = 1e-15
Identities = 106/513 (20%), Positives = 229/513 (44%), Gaps = 47/513 (9%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
KR + ++ ++ Y +E+ E QK K + I T+ ++ R NE++ +
Sbjct: 723 KRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQII-NTMTQDLRG--ANEKLAVAEV 779
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
+A ++ LS+ L++ A + + ++ + E S T R+++
Sbjct: 780 RAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSS 839
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYI---LNDSSKQTSIEIEQLNARVVEAETKLK 320
++ +++ + +L+ V+Q L+ + L D+ +Q E L+ E +
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETN-LHLNTKELLKNAQ 898
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
E+ +K+ L + + VA++++ Q+T K Q ++ D++ QL+ T
Sbjct: 899 KEIATLKQHLS------NMEVQVASQSS---QRTGKGQPSNKEDV----DDLVSQLRQTE 945
Query: 381 DQYGVAQRRIQSLTGEVEEIRG---NYEQALRVKRSVEQQYEES-QTRVNELTVINVNLS 436
+Q + R+++ T VE+ + + E++L ++ V ++ ++ + R+ E L
Sbjct: 946 EQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLE 1005
Query: 437 SSKAKIEQELAIVAAD----YDEITKELRIADERYQRVQTELKHTVEHL-----HEEQER 487
++E+E + D + + ++L + VQ E++ ++ +E+Q R
Sbjct: 1006 KKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQAR 1065
Query: 488 IVKIEAVKKSLEIEVK-NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
E K ++E + K + L + A+ K +SK+ + + +E + + +
Sbjct: 1066 RDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLL 1125
Query: 547 ETIKILRKKERQLKE----VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE------ 596
E ++ER LK+ + +CE+ +K LL D +EK S KV ++ +
Sbjct: 1126 ECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVS 1185
Query: 597 --QEGMSQQSVTRVRRF-QRELEAAEDRADVAE 626
+EG SQ+ + + RF +RE E AE R +VA+
Sbjct: 1186 LSEEGKSQEQILEILRFIRREKEIAETRFEVAQ 1218
Score = 58.8 bits (136), Expect = 6e-08
Identities = 83/422 (19%), Positives = 184/422 (43%), Gaps = 37/422 (8%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQT-----LLEESRRNVQNER 197
++R++ +E+EL + +N E Q A + + + +T ++E ++ + +
Sbjct: 1225 RQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKE 1284
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKA-LMESKAMNSCDSRVTESITETVRVRETSPTT 256
+ D Q + V + ++ A A L E M + ++ E + + R +
Sbjct: 1285 RLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVS 1344
Query: 257 CVVRINTE----LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARV 312
+TE L + + ++ +L E + + L I ++ T+ + L +
Sbjct: 1345 QQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGR---LKAEIARSNASLTNNQ--NLIQSL 1399
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
E K+++E I+K L +I +++ + KT ++K ++ Q E++ D+V
Sbjct: 1400 KEDLNKVRTEKETIQKDLDAKIIDIQEKV----KTITQVKKIGRRYKTQYEELKAQQDKV 1455
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE-------ESQTRV 425
++ + G Q + S+ E++E++ QA +S+E Q E E +T
Sbjct: 1456 ---METSAQSSGDHQEQHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEA 1511
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
L V L S +++ Q+L +++ +++ +E+ ++ K + HL
Sbjct: 1512 RNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAG-- 1569
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
VK + K++ E++ +N ++ ++ E + + + S+ E RI +E EL E + RH
Sbjct: 1570 ---VKDQLTKENEELKQRNGALDQQKDELDVRITALK--SQYEGRISRLERELREHQERH 1624
Query: 546 AE 547
E
Sbjct: 1625 LE 1626
Score = 52.0 bits (119), Expect = 7e-06
Identities = 93/512 (18%), Positives = 212/512 (41%), Gaps = 37/512 (7%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAI---AQTLLEESRRNVQNERMY 199
+K++ E+EKE + + E ++ K+ ++ Q L+ + + NE+
Sbjct: 1005 EKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQA 1064
Query: 200 KPDFQASRTLVNRDYTNLSKNVL-----AKALMESKAMNSCDSRVTESITETVRVRETSP 254
+ D Q + + ++ +AL +K S + V + + ET + E+
Sbjct: 1065 RRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQL 1124
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE----QLNA 310
C + + + ++ KQ L I S K + E LN
Sbjct: 1125 LECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNV 1184
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
+ E E K + ++ I + ++ + E +VA ++ ++ ++ +L E+Q +
Sbjct: 1185 SLSE-EGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLN 1243
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV 430
+ ++QVT + T + + + K +EQ ++ Q +V +L +
Sbjct: 1244 AEREKVQVTAKTM-AQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLEL 1302
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK--HTVEH---LHEEQ 485
+ L + A++ ++ ++ A+ + ++++ R Q + ++ K T E+ L E++
Sbjct: 1303 DILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKE 1362
Query: 486 ERIVKIEAVKKS---LEIEVKNISVRLEEVEANAIVGGKRIISKL----EARIKDME--- 535
+I+ + + L+ E+ + L N I K ++K+ E KD++
Sbjct: 1363 VHTKRIQQLTEEIGRLKAEIARSNASLTN-NQNLIQSLKEDLNKVRTEKETIQKDLDAKI 1421
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ-- 593
+++ E+ + + KI R+ + Q +E ++ ++D+ + Q S + Q VS+ + Q
Sbjct: 1422 IDIQEKVKTITQVKKIGRRYKTQYEE--LKAQQDKVMETSAQSSGDHQEQHVSVQEMQEL 1479
Query: 594 ---LAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L + E S+ ++V Q+ L E A
Sbjct: 1480 KETLNQAETKSKSLESQVENLQKTLSEKETEA 1511
Score = 49.2 bits (112), Expect = 5e-05
Identities = 58/324 (17%), Positives = 145/324 (44%), Gaps = 17/324 (5%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E L + E + L +E ++K+Q+ + ++ KT + + + + L E
Sbjct: 1228 VELLERELQELQDSLNAE----REKVQVTAKTMAQHEELMKKT--ETMNVVMETNKMLRE 1281
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+ ++ +Q+Q + + + +Q E+ E G + K+ +E+ + + R
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAE---KKLLEEDVKRWKAR 1338
Query: 425 VNELTVINVNLSSSK-AKIEQELAIVAADYDEITKEL-RIADE--RYQRVQTELKHTVEH 480
L + + + K+ E + ++T+E+ R+ E R T ++ ++
Sbjct: 1339 NQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQS 1398
Query: 481 LHEEQERI-VKIEAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELE 537
L E+ ++ + E ++K L+ ++ +I +++ + +G K +L+A+ +D +E
Sbjct: 1399 LKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQ-QDKVME 1457
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
+ + + ++ ++LKE + Q E K++ ++L+KT + R L EQ
Sbjct: 1458 TSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQ 1517
Query: 598 EGMSQQSVTRVRRFQRELEAAEDR 621
Q ++R+R+ ++ E++
Sbjct: 1518 TVQLQSELSRLRQDLQDRTTQEEQ 1541
Score = 48.0 bits (109), Expect = 1e-04
Identities = 97/508 (19%), Positives = 212/508 (41%), Gaps = 49/508 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSEL--RQKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
+K + I K LD KEV + + RQ+ R + A A LE++ + +Q
Sbjct: 412 EKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQ----- 466
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
R + D N +VL + +++ M +++ I + E + V+
Sbjct: 467 -------RLQEDTDKANKQSSVLER---DNRRMEIQVKDLSQQIRVLLMELEEARGNHVI 516
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-ARVVEAETK 318
R + E+ + D S +++ + + + + ++ L +++ + + +L R E +
Sbjct: 517 R-DEEVSSADISSSSEV--ISQHLVSYRNIEE--LQQQNQRLLVALRELGETREREEQET 571
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
S++T ++ KL+ +TELE L + + + L +I +Q + + V L
Sbjct: 572 TSSKITELQLKLESALTELE-QLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHA 630
Query: 379 -TLDQYGVAQRRIQSLTGEVEEIRG-----NYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+LD +A + T + +A+ K +++Q E + E
Sbjct: 631 SSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENE 690
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL---KHTVEHLHEEQERIV 489
+ K+++++ + + +I+ +L A +RY+ +Q + + + LHE +++
Sbjct: 691 KIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT 750
Query: 490 ----KIEAVKKSLEIEVK--NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
K E + ++ +++ N + + EV A + K ++ E R+ L E+R
Sbjct: 751 ATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQR 810
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+L + ++ ++ + E + K L +EK ++S K++L E +Q
Sbjct: 811 GQ----NLLLTNLQTIQGILERSETETK--QRLSSQIEKLEHEISHLKKKL---ENEVEQ 861
Query: 604 SVTRVRRFQRELEAAEDRADVAESNLSL 631
T R +L + + D E+NL L
Sbjct: 862 RHTLTRNLDVQLLDTKRQLD-TETNLHL 888
Score = 47.2 bits (107), Expect = 2e-04
Identities = 82/399 (20%), Positives = 175/399 (43%), Gaps = 37/399 (9%)
Query: 260 RINTELPAIDNSYLNQLNE-LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
R++ EL + + +LNE LKE+ +L + + D + + + ++ R+ + +
Sbjct: 133 RLSQELEYLTED-VKRLNEKLKESNTTKGELQLKL--DELQASDVSVKYREKRLEQEKEL 189
Query: 319 LKSEVTRIKKKLQIQITEL-ELSLDVAN-----KTNIDLQKT-IKKQSLQLTEIQTHYDE 371
L S+ T + +L+ + EL L + N K N++ +K + + Q+ ++T +
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEH 249
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+Q+ ++ L + A+ + S+ E+ +++ + ++S+ + NELT
Sbjct: 250 LQKHVEDLLTKLKEAKEQQASME---EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRA 306
Query: 432 NVNL-------SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
L + I+ L V D++ KE+ E+ R++ EL++ + L
Sbjct: 307 VEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEML---EKIGRLEKELENANDLLSAT 363
Query: 485 QERIV-----KIEAVKKSLEIEVKNISVRLEEVEA-NAIVG--GKRIISKLE-ARIKDME 535
+ + ++ A+ + K + ++ E NA V + ++ KLE RI
Sbjct: 364 KRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYL 423
Query: 536 LELDEEKRRHAETIKILRKK-ERQLKEVI---IQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E+ +E A +K R++ ER K V ++ E+ K I LQ+ +K +++ S+ +
Sbjct: 424 DEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLE 483
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLS 630
R E + ++R ELE A + + +S
Sbjct: 484 RDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVS 522
Score = 39.5 bits (88), Expect = 0.037
Identities = 50/240 (20%), Positives = 110/240 (45%), Gaps = 15/240 (6%)
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E + Y E++++L + ++ R QSL E+E++ N +AL K ++ E +Q
Sbjct: 49 ESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKL-NNQLKALTEK---NKELEIAQD 104
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
R I + +K ++E E + + +++EL E +R+ +LK + E
Sbjct: 105 R---NIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGE 161
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
Q ++ +++A ++ VK RLE+ + + ++L+ + ++ L L EK
Sbjct: 162 LQLKLDELQA----SDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDEL-LALGREKG 216
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
E +++ E + KE + + EE + + L+K + + ++ EQ+ ++
Sbjct: 217 N--EILELKCNLENK-KEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE 273
Score = 34.7 bits (76), Expect = 1.1
Identities = 56/326 (17%), Positives = 133/326 (40%), Gaps = 26/326 (7%)
Query: 273 LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE-TKLKSEVTRIKKKLQ 331
+N+ E + + + L+ + + K +EI Q ++++ T+ K E+ K+ L
Sbjct: 69 VNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLI 128
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
L L+ + L + +K+ + E+Q DE+Q V++ + R +
Sbjct: 129 RTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS-DVSV------KYREK 181
Query: 392 SLTGEVEEIRG-NYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK---AKIEQELA 447
L E E + N +K ++ + + NE+ + NL + K +++E+++
Sbjct: 182 RLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMN 241
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ + + K + + + + + E H E +K+ + KS +
Sbjct: 242 GLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADD------ 295
Query: 508 RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCE 567
E ++N + R + +L +K+ + K +++ + K++ KE++ +
Sbjct: 296 --SEAKSNELT---RAVEELHKLLKEAG---EANKAIQDHLLEVEQSKDQMEKEMLEKIG 347
Query: 568 EDQKNISLLQDSLEKTSQKVSIYKRQ 593
+K + D L T +K +I +
Sbjct: 348 RLEKELENANDLLSATKRKGAILSEE 373
Score = 32.3 bits (70), Expect = 5.6
Identities = 39/159 (24%), Positives = 76/159 (47%), Gaps = 21/159 (13%)
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
LE E N + K + +KLE + D + E+D K RH E K+ + E+Q E+
Sbjct: 9 LERTELNKLP--KSVQNKLEKFLADQQSEIDGLKGRH-EKFKV--ESEQQYFEI------ 57
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESN 628
+K +S Q+ L +++ + +L E ++ Q + + +ELE A+DR +S
Sbjct: 58 -EKRLSHSQERLVNETRECQSLRLEL---EKLNNQ-LKALTEKNKELEIAQDRNIAIQSQ 112
Query: 629 LSL----IRAKHRTFVTTSTVPGSQV-YLVQESRALSSE 662
+ + A+ R + T+ ++ YL ++ + L+ +
Sbjct: 113 FTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEK 151
>AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 84.6 bits (200), Expect = 1e-15
Identities = 106/513 (20%), Positives = 229/513 (44%), Gaps = 47/513 (9%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
KR + ++ ++ Y +E+ E QK K + I T+ ++ R NE++ +
Sbjct: 723 KRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQII-NTMTQDLRG--ANEKLAVAEV 779
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
+A ++ LS+ L++ A + + ++ + E S T R+++
Sbjct: 780 RAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSS 839
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYI---LNDSSKQTSIEIEQLNARVVEAETKLK 320
++ +++ + +L+ V+Q L+ + L D+ +Q E L+ E +
Sbjct: 840 QIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETN-LHLNTKELLKNAQ 898
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
E+ +K+ L + + VA++++ Q+T K Q ++ D++ QL+ T
Sbjct: 899 KEIATLKQHLS------NMEVQVASQSS---QRTGKGQPSNKEDV----DDLVSQLRQTE 945
Query: 381 DQYGVAQRRIQSLTGEVEEIRG---NYEQALRVKRSVEQQYEES-QTRVNELTVINVNLS 436
+Q + R+++ T VE+ + + E++L ++ V ++ ++ + R+ E L
Sbjct: 946 EQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLE 1005
Query: 437 SSKAKIEQELAIVAAD----YDEITKELRIADERYQRVQTELKHTVEHL-----HEEQER 487
++E+E + D + + ++L + VQ E++ ++ +E+Q R
Sbjct: 1006 KKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQAR 1065
Query: 488 IVKIEAVKKSLEIEVK-NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
E K ++E + K + L + A+ K +SK+ + + +E + + +
Sbjct: 1066 RDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLL 1125
Query: 547 ETIKILRKKERQLKE----VIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE------ 596
E ++ER LK+ + +CE+ +K LL D +EK S KV ++ +
Sbjct: 1126 ECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVS 1185
Query: 597 --QEGMSQQSVTRVRRF-QRELEAAEDRADVAE 626
+EG SQ+ + + RF +RE E AE R +VA+
Sbjct: 1186 LSEEGKSQEQILEILRFIRREKEIAETRFEVAQ 1218
Score = 58.8 bits (136), Expect = 6e-08
Identities = 83/422 (19%), Positives = 184/422 (43%), Gaps = 37/422 (8%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQT-----LLEESRRNVQNER 197
++R++ +E+EL + +N E Q A + + + +T ++E ++ + +
Sbjct: 1225 RQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKE 1284
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKA-LMESKAMNSCDSRVTESITETVRVRETSPTT 256
+ D Q + V + ++ A A L E M + ++ E + + R +
Sbjct: 1285 RLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVS 1344
Query: 257 CVVRINTE----LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARV 312
+TE L + + ++ +L E + + L I ++ T+ + L +
Sbjct: 1345 QQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGR---LKAEIARSNASLTNNQ--NLIQSL 1399
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
E K+++E I+K L +I +++ + KT ++K ++ Q E++ D+V
Sbjct: 1400 KEDLNKVRTEKETIQKDLDAKIIDIQEKV----KTITQVKKIGRRYKTQYEELKAQQDKV 1455
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE-------ESQTRV 425
++ + G Q + S+ E++E++ QA +S+E Q E E +T
Sbjct: 1456 ---METSAQSSGDHQEQHVSVQ-EMQELKETLNQAETKSKSLESQVENLQKTLSEKETEA 1511
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
L V L S +++ Q+L +++ +++ +E+ ++ K + HL
Sbjct: 1512 RNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAG-- 1569
Query: 486 ERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
VK + K++ E++ +N ++ ++ E + + + S+ E RI +E EL E + RH
Sbjct: 1570 ---VKDQLTKENEELKQRNGALDQQKDELDVRITALK--SQYEGRISRLERELREHQERH 1624
Query: 546 AE 547
E
Sbjct: 1625 LE 1626
Score = 52.0 bits (119), Expect = 7e-06
Identities = 93/512 (18%), Positives = 212/512 (41%), Gaps = 37/512 (7%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAI---AQTLLEESRRNVQNERMY 199
+K++ E+EKE + + E ++ K+ ++ Q L+ + + NE+
Sbjct: 1005 EKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQA 1064
Query: 200 KPDFQASRTLVNRDYTNLSKNVL-----AKALMESKAMNSCDSRVTESITETVRVRETSP 254
+ D Q + + ++ +AL +K S + V + + ET + E+
Sbjct: 1065 RRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQL 1124
Query: 255 TTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE----QLNA 310
C + + + ++ KQ L I S K + E LN
Sbjct: 1125 LECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNV 1184
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
+ E E K + ++ I + ++ + E +VA ++ ++ ++ +L E+Q +
Sbjct: 1185 SLSE-EGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLN 1243
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV 430
+ ++QVT + T + + + K +EQ ++ Q +V +L +
Sbjct: 1244 AEREKVQVTAKTM-AQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLEL 1302
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK--HTVEH---LHEEQ 485
+ L + A++ ++ ++ A+ + ++++ R Q + ++ K T E+ L E++
Sbjct: 1303 DILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKE 1362
Query: 486 ERIVKIEAVKKS---LEIEVKNISVRLEEVEANAIVGGKRIISKL----EARIKDME--- 535
+I+ + + L+ E+ + L N I K ++K+ E KD++
Sbjct: 1363 VHTKRIQQLTEEIGRLKAEIARSNASLTN-NQNLIQSLKEDLNKVRTEKETIQKDLDAKI 1421
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ-- 593
+++ E+ + + KI R+ + Q +E ++ ++D+ + Q S + Q VS+ + Q
Sbjct: 1422 IDIQEKVKTITQVKKIGRRYKTQYEE--LKAQQDKVMETSAQSSGDHQEQHVSVQEMQEL 1479
Query: 594 ---LAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
L + E S+ ++V Q+ L E A
Sbjct: 1480 KETLNQAETKSKSLESQVENLQKTLSEKETEA 1511
Score = 49.2 bits (112), Expect = 5e-05
Identities = 58/324 (17%), Positives = 145/324 (44%), Gaps = 17/324 (5%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+E L + E + L +E ++K+Q+ + ++ KT + + + + L E
Sbjct: 1228 VELLERELQELQDSLNAE----REKVQVTAKTMAQHEELMKKT--ETMNVVMETNKMLRE 1281
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
+ ++ +Q+Q + + + +Q E+ E G + K+ +E+ + + R
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAE---KKLLEEDVKRWKAR 1338
Query: 425 VNELTVINVNLSSSK-AKIEQELAIVAADYDEITKEL-RIADE--RYQRVQTELKHTVEH 480
L + + + K+ E + ++T+E+ R+ E R T ++ ++
Sbjct: 1339 NQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQS 1398
Query: 481 LHEEQERI-VKIEAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELE 537
L E+ ++ + E ++K L+ ++ +I +++ + +G K +L+A+ +D +E
Sbjct: 1399 LKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQ-QDKVME 1457
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
+ + + ++ ++LKE + Q E K++ ++L+KT + R L EQ
Sbjct: 1458 TSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQ 1517
Query: 598 EGMSQQSVTRVRRFQRELEAAEDR 621
Q ++R+R+ ++ E++
Sbjct: 1518 TVQLQSELSRLRQDLQDRTTQEEQ 1541
Score = 48.0 bits (109), Expect = 1e-04
Identities = 97/508 (19%), Positives = 212/508 (41%), Gaps = 49/508 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSEL--RQKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
+K + I K LD KEV + + RQ+ R + A A LE++ + +Q
Sbjct: 412 EKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQ----- 466
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
R + D N +VL + +++ M +++ I + E + V+
Sbjct: 467 -------RLQEDTDKANKQSSVLER---DNRRMEIQVKDLSQQIRVLLMELEEARGNHVI 516
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-ARVVEAETK 318
R + E+ + D S +++ + + + + ++ L +++ + + +L R E +
Sbjct: 517 R-DEEVSSADISSSSEV--ISQHLVSYRNIEE--LQQQNQRLLVALRELGETREREEQET 571
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
S++T ++ KL+ +TELE L + + + L +I +Q + + V L
Sbjct: 572 TSSKITELQLKLESALTELE-QLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHA 630
Query: 379 -TLDQYGVAQRRIQSLTGEVEEIRG-----NYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+LD +A + T + +A+ K +++Q E + E
Sbjct: 631 SSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENE 690
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL---KHTVEHLHEEQERIV 489
+ K+++++ + + +I+ +L A +RY+ +Q + + + LHE +++
Sbjct: 691 KIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT 750
Query: 490 ----KIEAVKKSLEIEVK--NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
K E + ++ +++ N + + EV A + K ++ E R+ L E+R
Sbjct: 751 ATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQR 810
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+L + ++ ++ + E + K L +EK ++S K++L E +Q
Sbjct: 811 GQ----NLLLTNLQTIQGILERSETETK--QRLSSQIEKLEHEISHLKKKL---ENEVEQ 861
Query: 604 SVTRVRRFQRELEAAEDRADVAESNLSL 631
T R +L + + D E+NL L
Sbjct: 862 RHTLTRNLDVQLLDTKRQLD-TETNLHL 888
Score = 47.2 bits (107), Expect = 2e-04
Identities = 82/399 (20%), Positives = 175/399 (43%), Gaps = 37/399 (9%)
Query: 260 RINTELPAIDNSYLNQLNE-LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
R++ EL + + +LNE LKE+ +L + + D + + + ++ R+ + +
Sbjct: 133 RLSQELEYLTED-VKRLNEKLKESNTTKGELQLKL--DELQASDVSVKYREKRLEQEKEL 189
Query: 319 LKSEVTRIKKKLQIQITEL-ELSLDVAN-----KTNIDLQKT-IKKQSLQLTEIQTHYDE 371
L S+ T + +L+ + EL L + N K N++ +K + + Q+ ++T +
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEH 249
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+Q+ ++ L + A+ + S+ E+ +++ + ++S+ + NELT
Sbjct: 250 LQKHVEDLLTKLKEAKEQQASME---EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRA 306
Query: 432 NVNL-------SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
L + I+ L V D++ KE+ E+ R++ EL++ + L
Sbjct: 307 VEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEML---EKIGRLEKELENANDLLSAT 363
Query: 485 QERIV-----KIEAVKKSLEIEVKNISVRLEEVEA-NAIVG--GKRIISKLE-ARIKDME 535
+ + ++ A+ + K + ++ E NA V + ++ KLE RI
Sbjct: 364 KRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYL 423
Query: 536 LELDEEKRRHAETIKILRKK-ERQLKEVI---IQCEEDQKNISLLQDSLEKTSQKVSIYK 591
E+ +E A +K R++ ER K V ++ E+ K I LQ+ +K +++ S+ +
Sbjct: 424 DEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLE 483
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLS 630
R E + ++R ELE A + + +S
Sbjct: 484 RDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVS 522
Score = 39.5 bits (88), Expect = 0.037
Identities = 50/240 (20%), Positives = 110/240 (45%), Gaps = 15/240 (6%)
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E + Y E++++L + ++ R QSL E+E++ N +AL K ++ E +Q
Sbjct: 49 ESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKL-NNQLKALTEK---NKELEIAQD 104
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
R I + +K ++E E + + +++EL E +R+ +LK + E
Sbjct: 105 R---NIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGE 161
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
Q ++ +++A ++ VK RLE+ + + ++L+ + ++ L L EK
Sbjct: 162 LQLKLDELQA----SDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDEL-LALGREKG 216
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
E +++ E + KE + + EE + + L+K + + ++ EQ+ ++
Sbjct: 217 N--EILELKCNLENK-KEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE 273
Score = 34.7 bits (76), Expect = 1.1
Identities = 56/326 (17%), Positives = 133/326 (40%), Gaps = 26/326 (7%)
Query: 273 LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE-TKLKSEVTRIKKKLQ 331
+N+ E + + + L+ + + K +EI Q ++++ T+ K E+ K+ L
Sbjct: 69 VNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLI 128
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
L L+ + L + +K+ + E+Q DE+Q V++ + R +
Sbjct: 129 RTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS-DVSV------KYREK 181
Query: 392 SLTGEVEEIRG-NYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK---AKIEQELA 447
L E E + N +K ++ + + NE+ + NL + K +++E+++
Sbjct: 182 RLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMN 241
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ + + K + + + + + E H E +K+ + KS +
Sbjct: 242 GLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADD------ 295
Query: 508 RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCE 567
E ++N + R + +L +K+ + K +++ + K++ KE++ +
Sbjct: 296 --SEAKSNELT---RAVEELHKLLKEAG---EANKAIQDHLLEVEQSKDQMEKEMLEKIG 347
Query: 568 EDQKNISLLQDSLEKTSQKVSIYKRQ 593
+K + D L T +K +I +
Sbjct: 348 RLEKELENANDLLSATKRKGAILSEE 373
Score = 32.3 bits (70), Expect = 5.6
Identities = 39/159 (24%), Positives = 76/159 (47%), Gaps = 21/159 (13%)
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
LE E N + K + +KLE + D + E+D K RH E K+ + E+Q E+
Sbjct: 9 LERTELNKLP--KSVQNKLEKFLADQQSEIDGLKGRH-EKFKV--ESEQQYFEI------ 57
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESN 628
+K +S Q+ L +++ + +L E ++ Q + + +ELE A+DR +S
Sbjct: 58 -EKRLSHSQERLVNETRECQSLRLEL---EKLNNQ-LKALTEKNKELEIAQDRNIAIQSQ 112
Query: 629 LSL----IRAKHRTFVTTSTVPGSQV-YLVQESRALSSE 662
+ + A+ R + T+ ++ YL ++ + L+ +
Sbjct: 113 FTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEK 151
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 83.8 bits (198), Expect = 2e-15
Identities = 113/589 (19%), Positives = 253/589 (42%), Gaps = 45/589 (7%)
Query: 62 KYRFNKPIRAYSEEDLTRISHDIAEQAK--RDLNTFTVGKRSPFSVIATAAAANVTKHVG 119
KY + +R +E+ +TR++ ++ ++A +DL T + +R +A V
Sbjct: 178 KYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELL-QRPGIEDVAVLKKELVQVQTL 236
Query: 120 VESVTVXXXXXXXXXXXXXXXXQKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAK 179
++++T+ + + E + E++ G + + + + K
Sbjct: 237 MDNMTLERERESEKLKDESKKFESQYASS-EATISQLRSELSKGPQ-EVRVYVQELQKLK 294
Query: 180 AIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRV 239
+ L ++++ +N + D+ N + + KN+ A + SR+
Sbjct: 295 SSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVS-KKNIQATLHQKDLDCQQLQSRL 353
Query: 240 TESITETVRVR-ETSPT-TCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDS 297
+ S T R+ E S ++ EL ++ Y + E K+ +Q ++ + L
Sbjct: 354 SASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGL--- 410
Query: 298 SKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKK 357
Q EI QL+++++E E +L R+K++ Q+ +L +D + DLQ + +
Sbjct: 411 --QLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKL---MDKEQQV-ADLQLKLSR 464
Query: 358 QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ 417
QL E T+ E+Q QL T Q+ Q QS T ++ E + + EQ LR +Q+
Sbjct: 465 LEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQK 524
Query: 418 YEESQTRVNE----LTVINVNLSSSKAKI---EQELAI----------VAADYDEITKEL 460
+ + + + ++++ AKI E E A+ + + ++T+ +
Sbjct: 525 IQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENV 584
Query: 461 RIADERYQRVQTELKHTVE----HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANA 516
+ E +++ Q L V+ HL Q+R++ +E L ++ ++ +++
Sbjct: 585 KNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQI 644
Query: 517 IVGGKRIISKLEARI---KDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNI 573
+ ++S A+ D++ LD + + + L K QL +V + ++ Q++
Sbjct: 645 KAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKHQELNKITTQLDQVTAKLQDKQEHC 704
Query: 574 SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
S L+ L++ +K +++ E EG + ++ E++A++++A
Sbjct: 705 SQLESHLKEYKEKYLSLEQKTEELEG----QIKKLEADSLEVKASKEQA 749
Score = 63.7 bits (148), Expect = 2e-09
Identities = 91/477 (19%), Positives = 201/477 (42%), Gaps = 20/477 (4%)
Query: 144 KRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDF 203
K +++ E L +KE + + + + K T L+ + + +
Sbjct: 438 KEQRQLSSE-KLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQAL 496
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
Q S T R+ N + VL + + + + + ++ + +S E + + E +I
Sbjct: 497 QQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKS-KENISLLEKEREDLYAKI-- 553
Query: 264 ELPAIDNSYLNQLNELKETVK-QFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+ + + LNQL E T++ + L+ + N S + E L+ +V E + L++
Sbjct: 554 QAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQ-ENLHDQVQEQKAHLRAA 612
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
R+ L+ + EL L+ + + L IK ++ L + + LQ LD
Sbjct: 613 QDRVLS-LETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLD- 670
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
AQ +Q E+ +I +Q + ++ + ++ + E ++L ++
Sbjct: 671 --TAQNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEEL 728
Query: 443 EQELAIVAADYDEI--TKELRIADERYQR-VQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
E ++ + AD E+ +KE + D + QR + T+L+ L ++ E +I + S
Sbjct: 729 EGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVS---STR 785
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
++++ S LE ++ K+ K + +D E E K +H E ++ +L
Sbjct: 786 LDLQKKSEALESIKQKLT---KQEEEKQILK-QDFETLSQETKIQHEELNNRIQTTVTEL 841
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
++V ++ E +S ++D L K S + K + ++ + ++ + + +EL+
Sbjct: 842 QKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELK 898
Score = 58.0 bits (134), Expect = 1e-07
Identities = 88/414 (21%), Positives = 179/414 (43%), Gaps = 38/414 (9%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLNARV----- 312
++ EL ++ + N LK+ K+ L I L SS+Q +IE L +
Sbjct: 928 QLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVL 987
Query: 313 --VEAETKLKSEVTRIKKKLQIQ---ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQT 367
E E KL+ ++T+ ++L + I+ L+ + + + +T LQ + +L +
Sbjct: 988 QKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQ 1047
Query: 368 HYDEVQRQLQVTLDQYGVAQRRI---QSLTGEVEEIRGNYEQ-ALRVKRSVEQQYEESQT 423
V+ +L + + + +I L E++ + EQ + + ++ ++++ + Q
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQD 1107
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITK---ELRIADERYQRVQTELKHTVEH 480
E ++ L + K+K+ + I EITK EL+ + T LK +
Sbjct: 1108 IQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQL 1167
Query: 481 LHEEQERIV-KIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII---SKLEARIKDMEL 536
L +++ + K +++K ++E E +N + ++V+ K I +KL + IK+ E+
Sbjct: 1168 LIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEV 1227
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS----------LEKTSQK 586
+ + + A+ + L V + + Q+ +S L+ LE T Q
Sbjct: 1228 GMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQN 1287
Query: 587 VSIYKRQLAEQ----EGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
+R L E+ EG ++ T+V QR+L+ ++ N SL + KH
Sbjct: 1288 NQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAVQELGRENQSL-QIKH 1340
Score = 55.6 bits (128), Expect = 5e-07
Identities = 70/362 (19%), Positives = 161/362 (44%), Gaps = 16/362 (4%)
Query: 280 KETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELEL 339
+ET Q ++L+ I ++ +++E+ A + E T +K +++++ L+ +E E
Sbjct: 821 QETKIQHEELNNRIQTTVTELQKVKMEK-EALMTELST-VKDKLSKVSDSLKNSKSEFEK 878
Query: 340 SLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEE 399
+DL+KT K+ QL + + Q++L+ +L++ A +++ E+
Sbjct: 879 ENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKL---ELNS 935
Query: 400 IRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE---- 455
++ QA + E++ ++ Q +NEL + ++ EL I E
Sbjct: 936 MQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENK 995
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEAN 515
+ ++L A + + ++ + + QE ++++ E E+ L+ VE
Sbjct: 996 LQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEK 1055
Query: 516 AIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL 575
+ + +IS +I + + E K A + KKE+QL+E ++ QK SL
Sbjct: 1056 LSLAQEDLISN-RNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSL 1114
Query: 576 LQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR--FQRELEAAEDRADVAESNLSLIR 633
+ L K++ ++ E + ++ +T++ +LE+ ++ ++ ++ LI+
Sbjct: 1115 KEKELVNEKSKLA----EIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQ 1170
Query: 634 AK 635
K
Sbjct: 1171 QK 1172
Score = 44.4 bits (100), Expect = 0.001
Identities = 48/230 (20%), Positives = 109/230 (47%), Gaps = 13/230 (5%)
Query: 412 RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQ 471
+S+EQQ EE+QT + + A++ E+A + + YDE A+++ R+
Sbjct: 138 QSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLT 197
Query: 472 TELKH---TVEHLHEE---QERIVKIEAVKKSL-EIEVKNISVRLE-EVEANAIVGGKRI 523
EL ++ L E + I + +KK L +++ ++ LE E E+ + +
Sbjct: 198 EELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDESKK 257
Query: 524 ISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
A + +L E + + +++ ++ ++LK + E QKN +L ++ L+K
Sbjct: 258 FESQYASSEATISQLRSELSKGPQEVRVYVQELQKLKSSV--NELTQKNQTLTENLLKKE 315
Query: 584 SQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
+ ++ +E +S++++ + Q++L+ + ++ ++ S SL R
Sbjct: 316 QDYTKLEEKH--NEESVSKKNI-QATLHQKDLDCQQLQSRLSASETSLHR 362
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/328 (18%), Positives = 129/328 (39%), Gaps = 27/328 (8%)
Query: 355 IKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
+ S +L ++ +E Q + + +++ L E+ +I+ Y++ ++ +
Sbjct: 130 VTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAA 189
Query: 415 EQQYEESQTRVN-ELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
EQ+ +N E TVI K ++ Q I D + KEL + E
Sbjct: 190 EQKVTRLTEELNKEATVI----QDLKTELLQRPGI--EDVAVLKKELVQVQTLMDNMTLE 243
Query: 474 LKHTVEHLHEEQERI----VKIEAVKKSLEIEVKN--ISVRLEEVEANAIVGGKRIISKL 527
+ E L +E ++ EA L E+ VR+ E + +++
Sbjct: 244 RERESEKLKDESKKFESQYASSEATISQLRSELSKGPQEVRVYVQELQKLKSSVNELTQK 303
Query: 528 EARIKDMELELDEE----KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ + L+ +++ + +H E + + L + + C++ Q +S + SL +
Sbjct: 304 NQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRI 363
Query: 584 SQKVS-------IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
++S K +L+E E Q ++ Q++ E E +S ++ + H
Sbjct: 364 HVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQL---H 420
Query: 637 RTFVTTSTVPGSQVYLVQESRALSSERL 664
+ T G ++E R LSSE+L
Sbjct: 421 SKLLETERQLGEAHGRLKEQRQLSSEKL 448
>BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein.
Length = 2002
Score = 81.0 bits (191), Expect = 1e-14
Identities = 84/495 (16%), Positives = 219/495 (44%), Gaps = 26/495 (5%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
Q+ +++L+ ++ SE Q+A K + + L ++++ +++ +++ + +
Sbjct: 1401 QQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAEL-QDTKLHLEGQQVRNHELEKK 1459
Query: 207 RTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSP-----TTCVVRI 261
+ + + + + + L K D + E+ + ++ E T VV +
Sbjct: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILN-----DSSKQTSIEIEQLNARVVEAE 316
EL I + L + KQ DL + + D T +EQL V+ E
Sbjct: 1520 EAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQLKQMEVQLE 1579
Query: 317 TKL--KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
+ K +V R K++L+ ++ L D N+ + + +K ++K L + + Q
Sbjct: 1580 EEYEDKQKVLREKRELEGKLATLS---DQVNRRDFESEKRLRKD---LKRTKALLADAQL 1633
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
L L ++R I L ++EE A++ ++++E + E+ +++++
Sbjct: 1634 MLD-HLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1692
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L +++++E + +E +++ ++++ + + +++ Q ++ +
Sbjct: 1693 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1752
Query: 495 KKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRK 554
K+ L+ +++ + ++E +E + + K ++S+ EA+I+++E L+ E+ + +K L
Sbjct: 1753 KQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERTQ----VKRLES 1806
Query: 555 KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+LKE + + E++ ++ ++ ++++ R E+ G + R + E
Sbjct: 1807 LASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHE 1866
Query: 615 LEAAEDRADVAESNL 629
LE + + A +L
Sbjct: 1867 LEMDLESLEAANQSL 1881
Score = 78.6 bits (185), Expect = 7e-14
Identities = 78/355 (21%), Positives = 173/355 (48%), Gaps = 18/355 (5%)
Query: 289 LSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
+ V + + + EI+QL +++ +AE K ++E+ +L+ +I+EL L T
Sbjct: 1247 IEVQLSEEQIRNKDEEIQQLRSKLEKAE-KERNELRLNSDRLESRISELTSELTDERNTG 1305
Query: 349 IDLQKTIKKQSLQ-------LTEIQTHYDEVQRQLQVTLDQYGVAQR-RIQSLTGEVEEI 400
+ + ++ + + E+QT YD +++Q++V + A+ R + GEV++
Sbjct: 1306 ESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD 1365
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS-SKAKIEQELAIVAADYDEITKE 459
E L+ +R+V ++ + ++ R+ + + + +K ++E+ L + AD +E +
Sbjct: 1366 DAGGEWRLKYERAV-REVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRA 1424
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L+ ++ QR+ EL+ T HL +Q R ++E ++ + E +S EE + +
Sbjct: 1425 LQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE---LSQAHEEAQREKLQR 1481
Query: 520 GK--RIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K R L A ++ +L+E+ A + + E +L+++ Q +D+ +++ ++
Sbjct: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1541
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA-EDRADVAESNLSL 631
L KV + +L EQ G + Q + ++++ + +LE ED+ V L
Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAG-TIQMLEQLKQMEVQLEEEYEDKQKVLREKREL 1595
Score = 66.5 bits (155), Expect = 3e-10
Identities = 85/407 (20%), Positives = 182/407 (44%), Gaps = 19/407 (4%)
Query: 144 KRMQEIEKEL-DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTL-LEESRRNVQN-ERMYK 200
+++ +E EL D+ +E + L + R AK Q L+E +Q E++ +
Sbjct: 1514 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQLKQ 1573
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
+ Q + +Y + K + K +E K D R+R+ T +
Sbjct: 1574 MEVQ-----LEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1628
Query: 261 INTELPA--IDNSYLN--QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ +L + NS + ++ +LK +++ + + + K +EIE L+ ++ +
Sbjct: 1629 ADAQLMLDHLKNSAPSKREIAQLKNQLEE-SEFTCAAAVKARKAMEVEIEDLHLQIDDI- 1686
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
K K+ + +LQ + E++ L+ + +L K K Q + +++Q QL
Sbjct: 1687 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQL 1746
Query: 377 QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNL 435
+ + Q ++Q+L +VE + + V R E + E +TR+ E T + L
Sbjct: 1747 EEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ-EAKIRELETRLEFERTQVK-RL 1804
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
S +++++ + + + D+ E+ +R+Q +L+ T E + E + + K
Sbjct: 1805 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1864
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
LE++++++ + ++A+ + KR I L+A I+D E+E DE +
Sbjct: 1865 HELEMDLESLEAANQSLQADLKLAFKR-IGDLQAAIED-EMESDENE 1909
Score = 55.6 bits (128), Expect = 5e-07
Identities = 76/374 (20%), Positives = 164/374 (43%), Gaps = 24/374 (6%)
Query: 280 KETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELEL 339
K ++F+D + + + +Q + L A E++ L+ ++ + ++L ++ + +L
Sbjct: 1387 KRLQQEFED-KLEVEQQNKRQLERRLGDLQADSEESQRALQ-QLKKKCQRLTAELQDTKL 1444
Query: 340 SLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEE 399
L+ N +L+K KQ +E+ ++E QR+ Q QR L E
Sbjct: 1445 HLEGQQVRNHELEK---KQRRFDSELSQAHEEAQREKL----QREKLQREKDMLLAEAFS 1497
Query: 400 IRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
++ E+ Q+ + + +++ +S AK++++L + A + +E
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
Query: 460 LRIADERYQRVQT--ELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
L DE+ +Q +LK L EE E K+ K+ LE ++ +S ++ + +
Sbjct: 1558 L---DEQAGTIQMLEQLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE 1614
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
++ + + +A + D +L LD K +I + K QL+E C K ++
Sbjct: 1615 KRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKN-QLEESEFTCAAAVKARKAME 1673
Query: 578 DSLEKTSQKVS-IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
+E ++ I K + A +E +S R QRE ++R + + +++ + KH
Sbjct: 1674 VEIEDLHLQIDDIAKAKTALEEQLS--------RLQREKNEIQNRLEEDQEDMNELMKKH 1725
Query: 637 RTFVTTSTVPGSQV 650
+ V ++ +Q+
Sbjct: 1726 KAAVAQASRDLAQI 1739
Score = 54.8 bits (126), Expect = 9e-07
Identities = 63/321 (19%), Positives = 151/321 (47%), Gaps = 23/321 (7%)
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
T ++ +++Q++E ++ ++ L+ ++K + E++ + D ++ ++ +
Sbjct: 1241 TTVRPLIEVQLSEEQIRNK--DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 1298
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE--ESQTRVNELTVINVNLSSSKAK 441
+ +S + ++ +A + + ++ QY+ + Q V E+ V+ L + A+
Sbjct: 1299 TDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AE 1357
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV-KKSLEI 500
I E+ D D+ E R+ +Y+R E+ T + L +E E +++E K+ LE
Sbjct: 1358 INGEV-----DDDDAGGEWRL---KYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER 1409
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+ ++ EE + A+ K+ +L A ++D +L L+ ++ R+ E L KK+R+
Sbjct: 1410 RLGDLQADSEESQ-RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE----LEKKQRRFD 1464
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQ----KVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ Q E+ + L ++ L++ + K+QL E++ +V + EL+
Sbjct: 1465 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
Query: 617 AAEDRADVAESNLSLIRAKHR 637
+ E++L+ ++ + R
Sbjct: 1525 DISSQESKDEASLAKVKKQLR 1545
Score = 52.8 bits (121), Expect = 4e-06
Identities = 58/311 (18%), Positives = 144/311 (46%), Gaps = 23/311 (7%)
Query: 333 QITELELSL-DVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQ--RR 389
++ LE L D++++ + D + ++ K QL +++ + + +L +Q G Q +
Sbjct: 1515 KVVSLEAELQDISSQESKD-EASLAKVKKQLRDLEAKVKDQEEELD---EQAGTIQMLEQ 1570
Query: 390 IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIV 449
++ + ++EE + ++ LR KR +E + +VN + K + L
Sbjct: 1571 LKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL-- 1628
Query: 450 AADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRL 509
AD + L+ + + + +LK+ +E VK +K++E+E++++ +++
Sbjct: 1629 -ADAQLMLDHLKNSAPSKREI-AQLKNQLEESEFTCAAAVK---ARKAMEVEIEDLHLQI 1683
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEK-------RRHAETIKILRKKERQLKEV 562
+++ A A + +S+L+ +++ L+E++ ++H + + Q+ ++
Sbjct: 1684 DDI-AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDL 1742
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
Q EE K LQ+ L+ +V ++ + ++ +S+Q ++R + LE +
Sbjct: 1743 QAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQE-AKIRELETRLEFERTQV 1801
Query: 623 DVAESNLSLIR 633
ES S ++
Sbjct: 1802 KRLESLASRLK 1812
>BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein.
Length = 887
Score = 79.4 bits (187), Expect = 4e-14
Identities = 111/457 (24%), Positives = 217/457 (47%), Gaps = 50/457 (10%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
R+ ++E E K V ELR G ++K I + E R + + E + Q
Sbjct: 458 RLLKLEMENQSLTKTVE---ELRTTVDSVEGNASK-ILKMEKENQRLSKKVEILENEIVQ 513
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
++L N NLSK+ LM+ KA E ET+R + + N
Sbjct: 514 EKQSLQNCQ--NLSKD-----LMKEKAQ-------LEKTIETLRENSERQIKILEQENEH 559
Query: 265 LPAIDNSYLNQLNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
L +S L Q +++ + D + IL++S K+TS ++ ++ + ++K E+
Sbjct: 560 LNQTVSS-LRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFE----KRQIKKEL 614
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQ------THYDEVQRQLQ 377
K+K + + ELE L K N LQK I + +I+ + + R+L+
Sbjct: 615 EHYKEKGE-RAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLK 673
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
TLD + +++SL E ++ E+ L ++R+VE + + ++ +L + N L S
Sbjct: 674 KTLDSFKNLTFQLESLEKENSQLD---EENLELRRNVES-LKCASMKMAQLQLENKELES 729
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
K ++++ L ++ A + + T+ L ++ YQ + E + + L ++I ++E+ +
Sbjct: 730 EKEQLKKGLELLKASFKK-TERLEVS---YQGLDIENQRLQKTLENSNKKIQQLESELQD 785
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE---LDEEKRRHAETIKILRK 554
LE+E + + LEE++ + KR + +LE K +E E L+++K++ + K LR
Sbjct: 786 LEMENQTLQKNLEELK----ISSKR-LEQLEKENKSLEQETSQLEKDKKQLEKENKRLR- 839
Query: 555 KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYK 591
++ ++K+ + EE+ I L+ + S+++ IYK
Sbjct: 840 QQAEIKDTTL--EENNVKIGNLEKENKTLSKEIGIYK 874
Score = 64.5 bits (150), Expect = 1e-09
Identities = 75/350 (21%), Positives = 160/350 (45%), Gaps = 21/350 (6%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S + S+E+ A++ +L+ + ++ Q ++ ++E+ L + N++L
Sbjct: 241 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQ-ELEQMEIELKRLQQENMNLLSDA 299
Query: 356 KKQSLQLTEIQTHYDEVQR--QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ + E+ ++ R +L+ + +Y I+ VEE++ + + L K
Sbjct: 300 RSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTM 359
Query: 414 VEQQYEESQTR---VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
+E Q E ++ R ++EL N+ L + +E E + +E+ +E + ++
Sbjct: 360 LEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 419
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI-SVRLEEVEANAIVGGKRIISKLEA 529
E H L + EA +KSL EV + S RL ++E + + +L
Sbjct: 420 MDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-QSLTKTVEELRT 478
Query: 530 RIKDME------LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ +E L++++E +R ++ ++IL + Q K+ + C+ K++ + LEKT
Sbjct: 479 TVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKT 538
Query: 584 SQKV---SIYKRQLAEQEGMS-QQSVTRVRRFQRELEAAEDRA-DVAESN 628
+ + S + ++ EQE Q+V+ +R QR +AE R D+ + N
Sbjct: 539 IETLRENSERQIKILEQENEHLNQTVSSLR--QRSQISAEARVKDIEKEN 586
Score = 62.5 bits (145), Expect = 5e-09
Identities = 104/506 (20%), Positives = 226/506 (44%), Gaps = 45/506 (8%)
Query: 143 KKRMQEIEKELD-LYEKEVNLGSELRQKAAMYRGK----SAKAIAQTLLEESRRNVQNER 197
K+ ++++E EL L ++ +NL S+ R A MYR + KA+ LE S + ER
Sbjct: 275 KQELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLE-SEVSRYKER 332
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
++ +F +R L ++ + L+E+K M T + ++ + E
Sbjct: 333 LHDIEFYKARV------EELKED--NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQL 384
Query: 258 VVRINT-ELPA-IDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA 315
+++ E+ +D + +L E T++ S+ D S E+EQ++ +
Sbjct: 385 KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSM----DESLHLGWELEQISRTSELS 440
Query: 316 ETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR- 374
E KS + + ++ +LE+ KT +L+ T+ ++I E QR
Sbjct: 441 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 500
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+V + + + Q + QSL + ++ ++++++E E S+ ++ L N +
Sbjct: 501 SKKVEILENEIVQEK-QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEH 559
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L+ + + + Q +I+ E R+ D ++ E K E + E ++ KIE
Sbjct: 560 LNQTVSSLRQR--------SQISAEARVKD-----IEKENKILHESIKETSSKLSKIEFE 606
Query: 495 KKSLEIEV---KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
K+ ++ E+ K R EE+E N + ++ L+ +I ++++ ++ + E +
Sbjct: 607 KRQIKKELEHYKEKGERAEELE-NELHHLEKENELLQKKITNLKITCEKIEALEQENSE- 664
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
L ++ R+LK+ + + KN++ +SLEK + ++ +L + + ++ +
Sbjct: 665 LERENRKLKKTL----DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 720
Query: 612 QRELEAAEDRADVAESNLSLIRAKHR 637
Q E + E + + L L++A +
Sbjct: 721 QLENKELESEKEQLKKGLELLKASFK 746
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 79.0 bits (186), Expect = 5e-14
Identities = 75/339 (22%), Positives = 163/339 (48%), Gaps = 16/339 (4%)
Query: 289 LSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
+ V + + + EI+QL +++ +AE K ++E+ +L+ +I+EL L T
Sbjct: 1260 IEVQLSEEQIRNKDEEIQQLRSKLEKAE-KERNELRLNSDRLESRISELTSELTDERNTG 1318
Query: 349 IDLQKTIKKQSLQ-------LTEIQTHYDEVQRQLQVTLDQYGVAQR-RIQSLTGEVEEI 400
+ + ++ + + E+QT YD +++Q++V + A+ R + GEV++
Sbjct: 1319 ESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD 1378
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS-SKAKIEQELAIVAADYDEITKE 459
E L+ +R+V ++ + ++ R+ + + + +K ++E+ L + AD +E +
Sbjct: 1379 DAGGEWRLKYERAV-REVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRA 1437
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L+ ++ QR+ EL+ T HL +Q R ++E ++ + E +S EE + +
Sbjct: 1438 LQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE---LSQAHEEAQREKLQR 1494
Query: 520 GK--RIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K R L A ++ +L+E+ A + + E +L+++ Q +D+ +++ ++
Sbjct: 1495 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1554
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
L KV + +L EQ G Q R + E+E
Sbjct: 1555 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1593
Score = 68.1 bits (159), Expect = 9e-11
Identities = 75/403 (18%), Positives = 177/403 (43%), Gaps = 11/403 (2%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++++ E+ELD + + + + + M + + ++ + + + + +
Sbjct: 1563 KVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1622
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ +Y + K + K +E K D R+R+ T + + +
Sbjct: 1623 QMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQ 1682
Query: 265 LPA--IDNSYLN--QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
L + NS + ++ +LK +++ + + + K +EIE L+ ++ + K K
Sbjct: 1683 LMLDHLKNSAPSKREIAQLKNQLEE-SEFTCAAAVKARKAMEVEIEDLHLQIDDI-AKAK 1740
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+ + +LQ + E++ L+ + +L K K Q + +++Q QL+
Sbjct: 1741 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1800
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSK 439
+ Q ++Q+L +VE + + V R E + E +TR+ E T + L S
Sbjct: 1801 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ-EAKIRELETRLEFERTQVK-RLESLA 1858
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
+++++ + + + D+ E+ +R+Q +L+ T E + E + + K LE
Sbjct: 1859 SRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELE 1918
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++++++ + ++A+ + KR I L+A I+D E+E DE +
Sbjct: 1919 MDLESLEAANQSLQADLKLAFKR-IGDLQAAIED-EMESDENE 1959
Score = 67.7 bits (158), Expect = 1e-10
Identities = 56/326 (17%), Positives = 157/326 (48%), Gaps = 14/326 (4%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
+++Q+ ++ E E + K +V R K++L+ ++ L D N+ + + +K ++K L
Sbjct: 1620 KLKQMEVQL-EEEYEDKQKVLREKRELEGKLATLS---DQVNRRDFESEKRLRKD---LK 1672
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+ + Q L L ++R I L ++EE A++ ++++E + E+
Sbjct: 1673 RTKALLADAQLMLD-HLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHL 1731
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
+++++ L +++++E + +E +++ ++++ + + +++
Sbjct: 1732 QIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQIND 1791
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
Q ++ + K+ L+ +++ + ++E +E + + K ++S+ EA+I+++E L+ E+
Sbjct: 1792 LQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERT 1849
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+ +K L +LKE + + E++ ++ ++ ++++ R E+ G +
Sbjct: 1850 Q----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR 1905
Query: 604 SVTRVRRFQRELEAAEDRADVAESNL 629
R + ELE + + A +L
Sbjct: 1906 KEAEASRKKHELEMDLESLEAANQSL 1931
Score = 63.3 bits (147), Expect = 3e-09
Identities = 67/361 (18%), Positives = 168/361 (46%), Gaps = 22/361 (6%)
Query: 284 KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL---QIQITELELS 340
+Q ++ + I + K S+E E + + E+K ++ + ++KK+L + ++ + E
Sbjct: 1513 QQLEEKDMDIAGFTQKVVSLEAELQD--ISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1570
Query: 341 LDVANKTNIDLQKTIKKQSLQLTEI-QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEE 399
LD T L++ + +++ + QTH E++ + + + Q++++ + ++EE
Sbjct: 1571 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1630
Query: 400 IRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ ++ LR KR +E + +VN + K + L AD +
Sbjct: 1631 EYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL---ADAQLMLDH 1687
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L+ + + + +LK+ +E VK +K++E+E++++ ++++++ A A
Sbjct: 1688 LKNSAPSKREI-AQLKNQLEESEFTCAAAVK---ARKAMEVEIEDLHLQIDDI-AKAKTA 1742
Query: 520 GKRIISKLEARIKDMELELDEEK-------RRHAETIKILRKKERQLKEVIIQCEEDQKN 572
+ +S+L+ +++ L+E++ ++H + + Q+ ++ Q EE K
Sbjct: 1743 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1802
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
LQ+ L+ +V ++ + ++ +S+Q ++R + LE + ES S +
Sbjct: 1803 KQELQEKLQALQSQVEFLEQSMVDKSLVSRQE-AKIRELETRLEFERTQVKRLESLASRL 1861
Query: 633 R 633
+
Sbjct: 1862 K 1862
Score = 57.6 bits (133), Expect = 1e-07
Identities = 74/364 (20%), Positives = 165/364 (45%), Gaps = 25/364 (6%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTR---IKKKLQIQITELELSLDVANKTNIDLQKTI 355
+Q + ++L A + + + L+ + R ++KK + +EL + + A + + +K
Sbjct: 1439 QQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQ 1498
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY---EQAL-RVK 411
+++ + L E + +++ + +D G Q+ + SL E+++I E +L +VK
Sbjct: 1499 REKDMLLAEAFSLKQQLEEK---DMDIAGFTQK-VVSLEAELQDISSQESKDEASLAKVK 1554
Query: 412 ---RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD-EITKELRIADERY 467
R +E + ++ + ++E L +K ++E E+ + + E+ +E
Sbjct: 1555 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1614
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
Q Q +LK L EE E K+ K+ LE ++ +S ++ + + ++ + +
Sbjct: 1615 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1674
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+A + D +L LD K +I + K QL+E C K ++ +E ++
Sbjct: 1675 KALLADAQLMLDHLKNSAPSKREIAQLKN-QLEESEFTCAAAVKARKAMEVEIEDLHLQI 1733
Query: 588 S-IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVP 646
I K + A +E +S R QRE ++R + + +++ + KH+ V ++
Sbjct: 1734 DDIAKAKTALEEQLS--------RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1785
Query: 647 GSQV 650
+Q+
Sbjct: 1786 LAQI 1789
Score = 54.8 bits (126), Expect = 9e-07
Identities = 63/321 (19%), Positives = 151/321 (47%), Gaps = 23/321 (7%)
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
T ++ +++Q++E ++ ++ L+ ++K + E++ + D ++ ++ +
Sbjct: 1254 TTVRPLIEVQLSEEQIRNK--DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 1311
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE--ESQTRVNELTVINVNLSSSKAK 441
+ +S + ++ +A + + ++ QY+ + Q V E+ V+ L + A+
Sbjct: 1312 TDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AE 1370
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV-KKSLEI 500
I E+ D D+ E R+ +Y+R E+ T + L +E E +++E K+ LE
Sbjct: 1371 INGEV-----DDDDAGGEWRL---KYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER 1422
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+ ++ EE + A+ K+ +L A ++D +L L+ ++ R+ E L KK+R+
Sbjct: 1423 RLGDLQADSEESQ-RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE----LEKKQRRFD 1477
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQ----KVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ Q E+ + L ++ L++ + K+QL E++ +V + EL+
Sbjct: 1478 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1537
Query: 617 AAEDRADVAESNLSLIRAKHR 637
+ E++L+ ++ + R
Sbjct: 1538 DISSQESKDEASLAKVKKQLR 1558
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 79.0 bits (186), Expect = 5e-14
Identities = 75/339 (22%), Positives = 163/339 (48%), Gaps = 16/339 (4%)
Query: 289 LSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
+ V + + + EI+QL +++ +AE K ++E+ +L+ +I+EL L T
Sbjct: 789 IEVQLSEEQIRNKDEEIQQLRSKLEKAE-KERNELRLNSDRLESRISELTSELTDERNTG 847
Query: 349 IDLQKTIKKQSLQ-------LTEIQTHYDEVQRQLQVTLDQYGVAQR-RIQSLTGEVEEI 400
+ + ++ + + E+QT YD +++Q++V + A+ R + GEV++
Sbjct: 848 ESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD 907
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS-SKAKIEQELAIVAADYDEITKE 459
E L+ +R+V ++ + ++ R+ + + + +K ++E+ L + AD +E +
Sbjct: 908 DAGGEWRLKYERAV-REVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRA 966
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L+ ++ QR+ EL+ T HL +Q R ++E ++ + E +S EE + +
Sbjct: 967 LQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE---LSQAHEEAQREKLQR 1023
Query: 520 GK--RIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K R L A ++ +L+E+ A + + E +L+++ Q +D+ +++ ++
Sbjct: 1024 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1083
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
L KV + +L EQ G Q R + E+E
Sbjct: 1084 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1122
Score = 68.1 bits (159), Expect = 9e-11
Identities = 75/403 (18%), Positives = 177/403 (43%), Gaps = 11/403 (2%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++++ E+ELD + + + + + M + + ++ + + + + +
Sbjct: 1092 KVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1151
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ +Y + K + K +E K D R+R+ T + + +
Sbjct: 1152 QMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQ 1211
Query: 265 LPA--IDNSYLN--QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
L + NS + ++ +LK +++ + + + K +EIE L+ ++ + K K
Sbjct: 1212 LMLDHLKNSAPSKREIAQLKNQLEE-SEFTCAAAVKARKAMEVEIEDLHLQIDDI-AKAK 1269
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+ + +LQ + E++ L+ + +L K K Q + +++Q QL+
Sbjct: 1270 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1329
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSK 439
+ Q ++Q+L +VE + + V R E + E +TR+ E T + L S
Sbjct: 1330 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ-EAKIRELETRLEFERTQVK-RLESLA 1387
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
+++++ + + + D+ E+ +R+Q +L+ T E + E + + K LE
Sbjct: 1388 SRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELE 1447
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++++++ + ++A+ + KR I L+A I+D E+E DE +
Sbjct: 1448 MDLESLEAANQSLQADLKLAFKR-IGDLQAAIED-EMESDENE 1488
Score = 67.7 bits (158), Expect = 1e-10
Identities = 56/326 (17%), Positives = 157/326 (48%), Gaps = 14/326 (4%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
+++Q+ ++ E E + K +V R K++L+ ++ L D N+ + + +K ++K L
Sbjct: 1149 KLKQMEVQL-EEEYEDKQKVLREKRELEGKLATLS---DQVNRRDFESEKRLRKD---LK 1201
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+ + Q L L ++R I L ++EE A++ ++++E + E+
Sbjct: 1202 RTKALLADAQLMLD-HLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHL 1260
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
+++++ L +++++E + +E +++ ++++ + + +++
Sbjct: 1261 QIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQIND 1320
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
Q ++ + K+ L+ +++ + ++E +E + + K ++S+ EA+I+++E L+ E+
Sbjct: 1321 LQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERT 1378
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+ +K L +LKE + + E++ ++ ++ ++++ R E+ G +
Sbjct: 1379 Q----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR 1434
Query: 604 SVTRVRRFQRELEAAEDRADVAESNL 629
R + ELE + + A +L
Sbjct: 1435 KEAEASRKKHELEMDLESLEAANQSL 1460
Score = 63.3 bits (147), Expect = 3e-09
Identities = 67/361 (18%), Positives = 168/361 (46%), Gaps = 22/361 (6%)
Query: 284 KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL---QIQITELELS 340
+Q ++ + I + K S+E E + + E+K ++ + ++KK+L + ++ + E
Sbjct: 1042 QQLEEKDMDIAGFTQKVVSLEAELQD--ISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1099
Query: 341 LDVANKTNIDLQKTIKKQSLQLTEI-QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEE 399
LD T L++ + +++ + QTH E++ + + + Q++++ + ++EE
Sbjct: 1100 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1159
Query: 400 IRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ ++ LR KR +E + +VN + K + L AD +
Sbjct: 1160 EYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL---ADAQLMLDH 1216
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L+ + + + +LK+ +E VK +K++E+E++++ ++++++ A A
Sbjct: 1217 LKNSAPSKREI-AQLKNQLEESEFTCAAAVK---ARKAMEVEIEDLHLQIDDI-AKAKTA 1271
Query: 520 GKRIISKLEARIKDMELELDEEK-------RRHAETIKILRKKERQLKEVIIQCEEDQKN 572
+ +S+L+ +++ L+E++ ++H + + Q+ ++ Q EE K
Sbjct: 1272 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1331
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
LQ+ L+ +V ++ + ++ +S+Q ++R + LE + ES S +
Sbjct: 1332 KQELQEKLQALQSQVEFLEQSMVDKSLVSRQE-AKIRELETRLEFERTQVKRLESLASRL 1390
Query: 633 R 633
+
Sbjct: 1391 K 1391
Score = 57.6 bits (133), Expect = 1e-07
Identities = 74/364 (20%), Positives = 165/364 (45%), Gaps = 25/364 (6%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTR---IKKKLQIQITELELSLDVANKTNIDLQKTI 355
+Q + ++L A + + + L+ + R ++KK + +EL + + A + + +K
Sbjct: 968 QQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQ 1027
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY---EQAL-RVK 411
+++ + L E + +++ + +D G Q+ + SL E+++I E +L +VK
Sbjct: 1028 REKDMLLAEAFSLKQQLEEK---DMDIAGFTQK-VVSLEAELQDISSQESKDEASLAKVK 1083
Query: 412 ---RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD-EITKELRIADERY 467
R +E + ++ + ++E L +K ++E E+ + + E+ +E
Sbjct: 1084 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1143
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
Q Q +LK L EE E K+ K+ LE ++ +S ++ + + ++ + +
Sbjct: 1144 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1203
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+A + D +L LD K +I + K QL+E C K ++ +E ++
Sbjct: 1204 KALLADAQLMLDHLKNSAPSKREIAQLKN-QLEESEFTCAAAVKARKAMEVEIEDLHLQI 1262
Query: 588 S-IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVP 646
I K + A +E +S R QRE ++R + + +++ + KH+ V ++
Sbjct: 1263 DDIAKAKTALEEQLS--------RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1314
Query: 647 GSQV 650
+Q+
Sbjct: 1315 LAQI 1318
Score = 54.8 bits (126), Expect = 9e-07
Identities = 63/321 (19%), Positives = 151/321 (47%), Gaps = 23/321 (7%)
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
T ++ +++Q++E ++ ++ L+ ++K + E++ + D ++ ++ +
Sbjct: 783 TTVRPLIEVQLSEEQIRNK--DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 840
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE--ESQTRVNELTVINVNLSSSKAK 441
+ +S + ++ +A + + ++ QY+ + Q V E+ V+ L + A+
Sbjct: 841 TDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AE 899
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV-KKSLEI 500
I E+ D D+ E R+ +Y+R E+ T + L +E E +++E K+ LE
Sbjct: 900 INGEV-----DDDDAGGEWRL---KYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER 951
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+ ++ EE + A+ K+ +L A ++D +L L+ ++ R+ E L KK+R+
Sbjct: 952 RLGDLQADSEESQ-RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE----LEKKQRRFD 1006
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQ----KVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ Q E+ + L ++ L++ + K+QL E++ +V + EL+
Sbjct: 1007 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1066
Query: 617 AAEDRADVAESNLSLIRAKHR 637
+ E++L+ ++ + R
Sbjct: 1067 DISSQESKDEASLAKVKKQLR 1087
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 79.0 bits (186), Expect = 5e-14
Identities = 121/605 (20%), Positives = 263/605 (43%), Gaps = 50/605 (8%)
Query: 41 KEHGVAAKPPHLPWNNER-ALDKYRFN-KPIRAYSEEDLTRISHDIAEQAKRDLNTFTVG 98
+ +GV HL + N++ A + R P+ D+ + D E+ K + TF +
Sbjct: 3 RRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIP 62
Query: 99 KRSPFSVIATAAAANVTKHVGVESVTVXXXXXXXXXXXXXXXXQKKRMQEIEKELDLYEK 158
K + + + + S +K + ++E++L
Sbjct: 63 KAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQL---HN 119
Query: 159 EVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLS 218
E+ L E+ QK K K + + L+E +N + + L+
Sbjct: 120 EMQLKDEMEQKCRTSNIKLDKIMKE--LDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQ 177
Query: 219 KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNE 278
+ KA E++ + ++ V+ + +++ S + + N +L + QL E
Sbjct: 178 R----KAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLA--NEKLSQLQK----QLEE 227
Query: 279 LKETVKQFDDLSVYILNDSSKQT-SI-EIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+ ++ D +V + ++ + SI ++E LN + E L++ ++ K +
Sbjct: 228 ANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYY----Q 283
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
L+ L+ + + I ++T +Q +EV + L+ L++ ++ Q +
Sbjct: 284 LQAILEAERRDRGHDSEMIGDLQARITSLQ---EEV-KHLKHNLEKVEGERKEAQDMLNH 339
Query: 397 VEEIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
E+ + N E L K +S++Q+ E+ VNE V L+ IE+ ++ + ++
Sbjct: 340 SEKEKNNLEIDLNYKLKSLQQRLEQE---VNEHKVTKARLTDKHQSIEEAKSVAMCEMEK 396
Query: 456 ITKELRIADERYQR--VQTELKHTV--EHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
KE R A E+ + VQ E + ++ L + Q+++ + K+ +E EVKN++++LE+
Sbjct: 397 KLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQ 456
Query: 512 VEANAIVGGKRIISKLEARIKDMELE----LDEEKRRHAET-IKILRKKERQLKEVIIQC 566
E+N KR++ + E + + E + L+++ ++ T ++ R E +L ++ Q
Sbjct: 457 -ESN-----KRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQY 510
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ----EGMSQQSVTRVRRFQRELEAAEDRA 622
++ + LQD LE ++YK Q+ E E +++++ +++ Q E E +
Sbjct: 511 RGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQL 570
Query: 623 DVAES 627
D+AE+
Sbjct: 571 DLAET 575
Score = 51.6 bits (118), Expect = 9e-06
Identities = 55/284 (19%), Positives = 134/284 (47%), Gaps = 32/284 (11%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS 359
Q + L+ + +++ KL+ +T K++++ ++ L L L+ + + LQ +K Q+
Sbjct: 414 QIEKQCSMLDVDLKQSQQKLE-HLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQA 472
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT-------GEVEEIRGNYE------- 405
+ ++ ++++++ L+ + + + LT G++ E++ E
Sbjct: 473 FEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFST 532
Query: 406 ----QALRVKRSVEQQYEESQTRVNELT------VINVNLSSSKAKIEQ-ELAIVAADYD 454
Q +K +E++ E+ ++ EL ++L+ +KA+ EQ ++ Y
Sbjct: 533 LYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYF 592
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVK-IEAVKKSLEIEVKNISVRLEEVE 513
E+T+E + A R ++ T+ HTV L E + K IE +++ E + ++ ++++ E
Sbjct: 593 ELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRR----ENEELTEKMKKAE 648
Query: 514 ANAIVGGKRIISKLEARI-KDMELELDEEKRRHAETIKILRKKE 556
+ + IS L+A K++ E + + + +I+ +K+
Sbjct: 649 EEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKD 692
Score = 50.4 bits (115), Expect = 2e-05
Identities = 89/524 (16%), Positives = 218/524 (41%), Gaps = 53/524 (10%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNE----- 196
+ ++ + +E E+ + ++ ++ Q + + K ++ Q LEE+ ++ E
Sbjct: 183 ENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQL--QKQLEEANDLLRTESDTAV 240
Query: 197 RMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTT 256
R+ K + S+++ + N + L SK+ D ++I E R +
Sbjct: 241 RLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSE 300
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ + + ++ + + L++ + + + + ++ ++EI+ LN ++ +
Sbjct: 301 MIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEID-LNYKLKSLQ 359
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNI-DLQKTIKKQSLQLTEIQTHYDEVQRQ 375
+L+ EV K + ++T+ S++ A + +++K +K++ + + ++++Q
Sbjct: 360 QRLEQEVNE-HKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQ 418
Query: 376 LQVTLDQYGVAQRRIQSLTG-------EVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+ +Q++++ LTG EV+ + EQ + ++ + + + L
Sbjct: 419 CSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNL 478
Query: 429 TVIN------VN-LSSSKAKIEQELAIVAADY---DEITKELRIADERYQRVQTELKHTV 478
+ +N L +K +E ELA + Y + +EL+ E Q T K V
Sbjct: 479 KGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQV 538
Query: 479 EHLHEE-----QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGG------------- 520
+ L EE +E + KI+ ++ E + + + E+ + G
Sbjct: 539 KELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQES 598
Query: 521 KRIISKLEARIKDME---LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K+ S+ I D + L+E + I+ILR++ +L E + + EE+ K
Sbjct: 599 KKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYK-----L 653
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR 621
+ E+ S + +++ + + + Q+V ++ + DR
Sbjct: 654 EKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDR 697
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 79.0 bits (186), Expect = 5e-14
Identities = 75/339 (22%), Positives = 163/339 (48%), Gaps = 16/339 (4%)
Query: 289 LSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
+ V + + + EI+QL +++ +AE K ++E+ +L+ +I+EL L T
Sbjct: 923 IEVQLSEEQIRNKDEEIQQLRSKLEKAE-KERNELRLNSDRLESRISELTSELTDERNTG 981
Query: 349 IDLQKTIKKQSLQ-------LTEIQTHYDEVQRQLQVTLDQYGVAQR-RIQSLTGEVEEI 400
+ + ++ + + E+QT YD +++Q++V + A+ R + GEV++
Sbjct: 982 ESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD 1041
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS-SKAKIEQELAIVAADYDEITKE 459
E L+ +R+V ++ + ++ R+ + + + +K ++E+ L + AD +E +
Sbjct: 1042 DAGGEWRLKYERAV-REVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRA 1100
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L+ ++ QR+ EL+ T HL +Q R ++E ++ + E +S EE + +
Sbjct: 1101 LQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE---LSQAHEEAQREKLQR 1157
Query: 520 GK--RIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K R L A ++ +L+E+ A + + E +L+++ Q +D+ +++ ++
Sbjct: 1158 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1217
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
L KV + +L EQ G Q R + E+E
Sbjct: 1218 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1256
Score = 68.1 bits (159), Expect = 9e-11
Identities = 75/403 (18%), Positives = 177/403 (43%), Gaps = 11/403 (2%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++++ E+ELD + + + + + M + + ++ + + + + +
Sbjct: 1226 KVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1285
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ +Y + K + K +E K D R+R+ T + + +
Sbjct: 1286 QMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQ 1345
Query: 265 LPA--IDNSYLN--QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
L + NS + ++ +LK +++ + + + K +EIE L+ ++ + K K
Sbjct: 1346 LMLDHLKNSAPSKREIAQLKNQLEE-SEFTCAAAVKARKAMEVEIEDLHLQIDDI-AKAK 1403
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+ + +LQ + E++ L+ + +L K K Q + +++Q QL+
Sbjct: 1404 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1463
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSK 439
+ Q ++Q+L +VE + + V R E + E +TR+ E T + L S
Sbjct: 1464 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ-EAKIRELETRLEFERTQVK-RLESLA 1521
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
+++++ + + + D+ E+ +R+Q +L+ T E + E + + K LE
Sbjct: 1522 SRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELE 1581
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++++++ + ++A+ + KR I L+A I+D E+E DE +
Sbjct: 1582 MDLESLEAANQSLQADLKLAFKR-IGDLQAAIED-EMESDENE 1622
Score = 67.7 bits (158), Expect = 1e-10
Identities = 56/326 (17%), Positives = 157/326 (48%), Gaps = 14/326 (4%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
+++Q+ ++ E E + K +V R K++L+ ++ L D N+ + + +K ++K L
Sbjct: 1283 KLKQMEVQL-EEEYEDKQKVLREKRELEGKLATLS---DQVNRRDFESEKRLRKD---LK 1335
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+ + Q L L ++R I L ++EE A++ ++++E + E+
Sbjct: 1336 RTKALLADAQLMLD-HLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHL 1394
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
+++++ L +++++E + +E +++ ++++ + + +++
Sbjct: 1395 QIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQIND 1454
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
Q ++ + K+ L+ +++ + ++E +E + + K ++S+ EA+I+++E L+ E+
Sbjct: 1455 LQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERT 1512
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+ +K L +LKE + + E++ ++ ++ ++++ R E+ G +
Sbjct: 1513 Q----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR 1568
Query: 604 SVTRVRRFQRELEAAEDRADVAESNL 629
R + ELE + + A +L
Sbjct: 1569 KEAEASRKKHELEMDLESLEAANQSL 1594
Score = 63.3 bits (147), Expect = 3e-09
Identities = 67/361 (18%), Positives = 168/361 (46%), Gaps = 22/361 (6%)
Query: 284 KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL---QIQITELELS 340
+Q ++ + I + K S+E E + + E+K ++ + ++KK+L + ++ + E
Sbjct: 1176 QQLEEKDMDIAGFTQKVVSLEAELQD--ISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1233
Query: 341 LDVANKTNIDLQKTIKKQSLQLTEI-QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEE 399
LD T L++ + +++ + QTH E++ + + + Q++++ + ++EE
Sbjct: 1234 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1293
Query: 400 IRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ ++ LR KR +E + +VN + K + L AD +
Sbjct: 1294 EYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL---ADAQLMLDH 1350
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L+ + + + +LK+ +E VK +K++E+E++++ ++++++ A A
Sbjct: 1351 LKNSAPSKREI-AQLKNQLEESEFTCAAAVK---ARKAMEVEIEDLHLQIDDI-AKAKTA 1405
Query: 520 GKRIISKLEARIKDMELELDEEK-------RRHAETIKILRKKERQLKEVIIQCEEDQKN 572
+ +S+L+ +++ L+E++ ++H + + Q+ ++ Q EE K
Sbjct: 1406 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1465
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
LQ+ L+ +V ++ + ++ +S+Q ++R + LE + ES S +
Sbjct: 1466 KQELQEKLQALQSQVEFLEQSMVDKSLVSRQE-AKIRELETRLEFERTQVKRLESLASRL 1524
Query: 633 R 633
+
Sbjct: 1525 K 1525
Score = 57.6 bits (133), Expect = 1e-07
Identities = 74/364 (20%), Positives = 165/364 (45%), Gaps = 25/364 (6%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTR---IKKKLQIQITELELSLDVANKTNIDLQKTI 355
+Q + ++L A + + + L+ + R ++KK + +EL + + A + + +K
Sbjct: 1102 QQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQ 1161
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY---EQAL-RVK 411
+++ + L E + +++ + +D G Q+ + SL E+++I E +L +VK
Sbjct: 1162 REKDMLLAEAFSLKQQLEEK---DMDIAGFTQK-VVSLEAELQDISSQESKDEASLAKVK 1217
Query: 412 ---RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD-EITKELRIADERY 467
R +E + ++ + ++E L +K ++E E+ + + E+ +E
Sbjct: 1218 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1277
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
Q Q +LK L EE E K+ K+ LE ++ +S ++ + + ++ + +
Sbjct: 1278 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1337
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+A + D +L LD K +I + K QL+E C K ++ +E ++
Sbjct: 1338 KALLADAQLMLDHLKNSAPSKREIAQLKN-QLEESEFTCAAAVKARKAMEVEIEDLHLQI 1396
Query: 588 S-IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVP 646
I K + A +E +S R QRE ++R + + +++ + KH+ V ++
Sbjct: 1397 DDIAKAKTALEEQLS--------RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1448
Query: 647 GSQV 650
+Q+
Sbjct: 1449 LAQI 1452
Score = 54.8 bits (126), Expect = 9e-07
Identities = 63/321 (19%), Positives = 151/321 (47%), Gaps = 23/321 (7%)
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
T ++ +++Q++E ++ ++ L+ ++K + E++ + D ++ ++ +
Sbjct: 917 TTVRPLIEVQLSEEQIRNK--DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 974
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE--ESQTRVNELTVINVNLSSSKAK 441
+ +S + ++ +A + + ++ QY+ + Q V E+ V+ L + A+
Sbjct: 975 TDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AE 1033
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV-KKSLEI 500
I E+ D D+ E R+ +Y+R E+ T + L +E E +++E K+ LE
Sbjct: 1034 INGEV-----DDDDAGGEWRL---KYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER 1085
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+ ++ EE + A+ K+ +L A ++D +L L+ ++ R+ E L KK+R+
Sbjct: 1086 RLGDLQADSEESQ-RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE----LEKKQRRFD 1140
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQ----KVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ Q E+ + L ++ L++ + K+QL E++ +V + EL+
Sbjct: 1141 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1200
Query: 617 AAEDRADVAESNLSLIRAKHR 637
+ E++L+ ++ + R
Sbjct: 1201 DISSQESKDEASLAKVKKQLR 1221
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 79.0 bits (186), Expect = 5e-14
Identities = 75/339 (22%), Positives = 163/339 (48%), Gaps = 16/339 (4%)
Query: 289 LSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
+ V + + + EI+QL +++ +AE K ++E+ +L+ +I+EL L T
Sbjct: 1239 IEVQLSEEQIRNKDEEIQQLRSKLEKAE-KERNELRLNSDRLESRISELTSELTDERNTG 1297
Query: 349 IDLQKTIKKQSLQ-------LTEIQTHYDEVQRQLQVTLDQYGVAQR-RIQSLTGEVEEI 400
+ + ++ + + E+QT YD +++Q++V + A+ R + GEV++
Sbjct: 1298 ESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD 1357
Query: 401 RGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS-SKAKIEQELAIVAADYDEITKE 459
E L+ +R+V ++ + ++ R+ + + + +K ++E+ L + AD +E +
Sbjct: 1358 DAGGEWRLKYERAV-REVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRA 1416
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L+ ++ QR+ EL+ T HL +Q R ++E ++ + E +S EE + +
Sbjct: 1417 LQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE---LSQAHEEAQREKLQR 1473
Query: 520 GK--RIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ 577
K R L A ++ +L+E+ A + + E +L+++ Q +D+ +++ ++
Sbjct: 1474 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1533
Query: 578 DSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
L KV + +L EQ G Q R + E+E
Sbjct: 1534 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1572
Score = 68.1 bits (159), Expect = 9e-11
Identities = 75/403 (18%), Positives = 177/403 (43%), Gaps = 11/403 (2%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++++ E+ELD + + + + + M + + ++ + + + + +
Sbjct: 1542 KVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1601
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ +Y + K + K +E K D R+R+ T + + +
Sbjct: 1602 QMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQ 1661
Query: 265 LPA--IDNSYLN--QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
L + NS + ++ +LK +++ + + + K +EIE L+ ++ + K K
Sbjct: 1662 LMLDHLKNSAPSKREIAQLKNQLEE-SEFTCAAAVKARKAMEVEIEDLHLQIDDI-AKAK 1719
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+ + +LQ + E++ L+ + +L K K Q + +++Q QL+
Sbjct: 1720 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1779
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-ELTVINVNLSSSK 439
+ Q ++Q+L +VE + + V R E + E +TR+ E T + L S
Sbjct: 1780 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ-EAKIRELETRLEFERTQVK-RLESLA 1837
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
+++++ + + + D+ E+ +R+Q +L+ T E + E + + K LE
Sbjct: 1838 SRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELE 1897
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++++++ + ++A+ + KR I L+A I+D E+E DE +
Sbjct: 1898 MDLESLEAANQSLQADLKLAFKR-IGDLQAAIED-EMESDENE 1938
Score = 67.7 bits (158), Expect = 1e-10
Identities = 56/326 (17%), Positives = 157/326 (48%), Gaps = 14/326 (4%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
+++Q+ ++ E E + K +V R K++L+ ++ L D N+ + + +K ++K L
Sbjct: 1599 KLKQMEVQL-EEEYEDKQKVLREKRELEGKLATLS---DQVNRRDFESEKRLRKD---LK 1651
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+ + Q L L ++R I L ++EE A++ ++++E + E+
Sbjct: 1652 RTKALLADAQLMLD-HLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHL 1710
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
+++++ L +++++E + +E +++ ++++ + + +++
Sbjct: 1711 QIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQIND 1770
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
Q ++ + K+ L+ +++ + ++E +E + + K ++S+ EA+I+++E L+ E+
Sbjct: 1771 LQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERT 1828
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+ +K L +LKE + + E++ ++ ++ ++++ R E+ G +
Sbjct: 1829 Q----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR 1884
Query: 604 SVTRVRRFQRELEAAEDRADVAESNL 629
R + ELE + + A +L
Sbjct: 1885 KEAEASRKKHELEMDLESLEAANQSL 1910
Score = 63.3 bits (147), Expect = 3e-09
Identities = 67/361 (18%), Positives = 168/361 (46%), Gaps = 22/361 (6%)
Query: 284 KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL---QIQITELELS 340
+Q ++ + I + K S+E E + + E+K ++ + ++KK+L + ++ + E
Sbjct: 1492 QQLEEKDMDIAGFTQKVVSLEAELQD--ISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1549
Query: 341 LDVANKTNIDLQKTIKKQSLQLTEI-QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEE 399
LD T L++ + +++ + QTH E++ + + + Q++++ + ++EE
Sbjct: 1550 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1609
Query: 400 IRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE 459
+ ++ LR KR +E + +VN + K + L AD +
Sbjct: 1610 EYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL---ADAQLMLDH 1666
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L+ + + + +LK+ +E VK +K++E+E++++ ++++++ A A
Sbjct: 1667 LKNSAPSKREI-AQLKNQLEESEFTCAAAVK---ARKAMEVEIEDLHLQIDDI-AKAKTA 1721
Query: 520 GKRIISKLEARIKDMELELDEEK-------RRHAETIKILRKKERQLKEVIIQCEEDQKN 572
+ +S+L+ +++ L+E++ ++H + + Q+ ++ Q EE K
Sbjct: 1722 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1781
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
LQ+ L+ +V ++ + ++ +S+Q ++R + LE + ES S +
Sbjct: 1782 KQELQEKLQALQSQVEFLEQSMVDKSLVSRQE-AKIRELETRLEFERTQVKRLESLASRL 1840
Query: 633 R 633
+
Sbjct: 1841 K 1841
Score = 57.6 bits (133), Expect = 1e-07
Identities = 74/364 (20%), Positives = 165/364 (45%), Gaps = 25/364 (6%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTR---IKKKLQIQITELELSLDVANKTNIDLQKTI 355
+Q + ++L A + + + L+ + R ++KK + +EL + + A + + +K
Sbjct: 1418 QQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQ 1477
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY---EQAL-RVK 411
+++ + L E + +++ + +D G Q+ + SL E+++I E +L +VK
Sbjct: 1478 REKDMLLAEAFSLKQQLEEK---DMDIAGFTQK-VVSLEAELQDISSQESKDEASLAKVK 1533
Query: 412 ---RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD-EITKELRIADERY 467
R +E + ++ + ++E L +K ++E E+ + + E+ +E
Sbjct: 1534 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1593
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
Q Q +LK L EE E K+ K+ LE ++ +S ++ + + ++ + +
Sbjct: 1594 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1653
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+A + D +L LD K +I + K QL+E C K ++ +E ++
Sbjct: 1654 KALLADAQLMLDHLKNSAPSKREIAQLKN-QLEESEFTCAAAVKARKAMEVEIEDLHLQI 1712
Query: 588 S-IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVP 646
I K + A +E +S R QRE ++R + + +++ + KH+ V ++
Sbjct: 1713 DDIAKAKTALEEQLS--------RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1764
Query: 647 GSQV 650
+Q+
Sbjct: 1765 LAQI 1768
Score = 54.8 bits (126), Expect = 9e-07
Identities = 63/321 (19%), Positives = 151/321 (47%), Gaps = 23/321 (7%)
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
T ++ +++Q++E ++ ++ L+ ++K + E++ + D ++ ++ +
Sbjct: 1233 TTVRPLIEVQLSEEQIRNK--DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 1290
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE--ESQTRVNELTVINVNLSSSKAK 441
+ +S + ++ +A + + ++ QY+ + Q V E+ V+ L + A+
Sbjct: 1291 TDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AE 1349
Query: 442 IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV-KKSLEI 500
I E+ D D+ E R+ +Y+R E+ T + L +E E +++E K+ LE
Sbjct: 1350 INGEV-----DDDDAGGEWRL---KYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER 1401
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+ ++ EE + A+ K+ +L A ++D +L L+ ++ R+ E L KK+R+
Sbjct: 1402 RLGDLQADSEESQ-RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE----LEKKQRRFD 1456
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQ----KVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+ Q E+ + L ++ L++ + K+QL E++ +V + EL+
Sbjct: 1457 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1516
Query: 617 AAEDRADVAESNLSLIRAKHR 637
+ E++L+ ++ + R
Sbjct: 1517 DISSQESKDEASLAKVKKQLR 1537
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 protein.
Length = 1354
Score = 78.6 bits (185), Expect = 7e-14
Identities = 121/603 (20%), Positives = 262/603 (43%), Gaps = 50/603 (8%)
Query: 43 HGVAAKPPHLPWNNER-ALDKYRFN-KPIRAYSEEDLTRISHDIAEQAKRDLNTFTVGKR 100
+GV HL + N++ A + R P+ D+ + D E+ K + TF + K
Sbjct: 327 NGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKA 386
Query: 101 SPFSVIATAAAANVTKHVGVESVTVXXXXXXXXXXXXXXXXQKKRMQEIEKELDLYEKEV 160
+ + + + S +K + ++E++L E+
Sbjct: 387 FVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQL---HNEM 443
Query: 161 NLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKN 220
L E+ QK K K + + L+E +N + + L+ +
Sbjct: 444 QLKDEMEQKCRTSNIKLDKIMKE--LDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQR- 500
Query: 221 VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELK 280
KA E++ + ++ V+ + +++ S + + N +L + QL E
Sbjct: 501 ---KAEQENEKRRNVENEVSTLKNQLEDLKKVSQNSQLA--NEKLSQLQK----QLEEAN 551
Query: 281 ETVKQFDDLSVYILNDSSKQT-SI-EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELE 338
+ ++ D +V + ++ + SI ++E LN + E L++ ++ K +L+
Sbjct: 552 DLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYY----QLQ 607
Query: 339 LSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE 398
L+ + + I ++T +Q +EV + L+ L++ ++ Q + E
Sbjct: 608 AILEAERRDRGHDSEMIGDLQARITSLQ---EEV-KHLKHNLEKVEGERKEAQDMLNHSE 663
Query: 399 EIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
+ + N E L K +S++Q+ E+ VNE V L+ IE+ ++ + ++
Sbjct: 664 KEKNNLEIDLNYKLKSLQQRLEQE---VNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL 720
Query: 458 KELRIADERYQR--VQTELKHTV--EHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
KE R A E+ + VQ E + ++ L + Q+++ + K+ +E EVKN++++LE+ E
Sbjct: 721 KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQ-E 779
Query: 514 ANAIVGGKRIISKLEARIKDMELE----LDEEKRRHAET-IKILRKKERQLKEVIIQCEE 568
+N KR++ + E + + E + L+++ ++ T ++ R E +L ++ Q
Sbjct: 780 SN-----KRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRG 834
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQ----EGMSQQSVTRVRRFQRELEAAEDRADV 624
++ + LQD LE ++YK Q+ E E +++++ +++ Q E E + D+
Sbjct: 835 NEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDL 894
Query: 625 AES 627
AE+
Sbjct: 895 AET 897
Score = 60.1 bits (139), Expect = 2e-08
Identities = 71/377 (18%), Positives = 173/377 (45%), Gaps = 41/377 (10%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS 359
Q + L+ + +++ KL+ +T K++++ ++ L L L+ + + LQ +K Q+
Sbjct: 736 QIEKQCSMLDVDLKQSQQKLE-HLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQA 794
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT-------GEVEEIRGNYE------- 405
+ ++ ++++++ L+ + + + LT G++ E++ E
Sbjct: 795 FEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFST 854
Query: 406 ----QALRVKRSVEQQYEESQTRVNELT------VINVNLSSSKAKIEQ-ELAIVAADYD 454
Q +K +E++ E+ ++ EL ++L+ +KA+ EQ ++ Y
Sbjct: 855 LYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYF 914
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVK-IEAVKKSLEIEVKNISVRLEEVE 513
E+T+E + A R ++ T+ HTV L E + K IE +++ E + ++ R+++ E
Sbjct: 915 ELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRR----ENEELTERMKKAE 970
Query: 514 ANAIVGGKRIISKLEARI-KDMELELDEEKRRHAETIKILRKKERQL------KEVIIQC 566
+ + IS L+A K++ E + + + +I+ +K+ ++ + + +
Sbjct: 971 EEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKK 1030
Query: 567 EEDQKNISL-LQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVA 625
E++ + + L L EK +Q V ++++L + + + Q +L + E +D+
Sbjct: 1031 EKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKE--SDIE 1088
Query: 626 ESNLSLIRAKHRTFVTT 642
+ L+ T V +
Sbjct: 1089 QLRAKLLDLSDSTSVAS 1105
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 78.2 bits (184), Expect = 9e-14
Identities = 121/603 (20%), Positives = 262/603 (43%), Gaps = 50/603 (8%)
Query: 43 HGVAAKPPHLPWNNER-ALDKYRFN-KPIRAYSEEDLTRISHDIAEQAKRDLNTFTVGKR 100
+GV HL + N++ A + R P+ D+ + D E+ K + TF + K
Sbjct: 327 NGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKA 386
Query: 101 SPFSVIATAAAANVTKHVGVESVTVXXXXXXXXXXXXXXXXQKKRMQEIEKELDLYEKEV 160
+ + + + S +K + ++E++L E+
Sbjct: 387 FVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQL---HNEM 443
Query: 161 NLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKN 220
L E+ QK K K + + L+E +N + + L+ +
Sbjct: 444 QLKDEMEQKCRTSNIKLDKIMKE--LDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQR- 500
Query: 221 VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELK 280
KA E++ + ++ V+ + +++ S + + N +L + QL E
Sbjct: 501 ---KAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLA--NEKLSQLQK----QLEEAN 551
Query: 281 ETVKQFDDLSVYILNDSSKQT-SI-EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELE 338
+ ++ D +V + ++ + SI ++E LN + E L++ ++ K +L+
Sbjct: 552 DLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYY----QLQ 607
Query: 339 LSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE 398
L+ + + I ++T +Q +EV + L+ L++ ++ Q + E
Sbjct: 608 AILEAERRDRGHDSEMIGDLQARITSLQ---EEV-KHLKHNLEKVEGERKEAQDMLNHSE 663
Query: 399 EIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
+ + N E L K +S++Q+ E+ VNE V L+ IE+ ++ + ++
Sbjct: 664 KEKNNLEIDLNYKLKSLQQRLEQE---VNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL 720
Query: 458 KELRIADERYQR--VQTELKHTV--EHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
KE R A E+ + VQ E + ++ L + Q+++ + K+ +E EVKN++++LE+ E
Sbjct: 721 KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQ-E 779
Query: 514 ANAIVGGKRIISKLEARIKDMELE----LDEEKRRHAET-IKILRKKERQLKEVIIQCEE 568
+N KR++ + E + + E + L+++ ++ T ++ R E +L ++ Q
Sbjct: 780 SN-----KRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRG 834
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQ----EGMSQQSVTRVRRFQRELEAAEDRADV 624
++ + LQD LE ++YK Q+ E E +++++ +++ Q E E + D+
Sbjct: 835 NEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDL 894
Query: 625 AES 627
AE+
Sbjct: 895 AET 897
Score = 58.8 bits (136), Expect = 6e-08
Identities = 70/377 (18%), Positives = 173/377 (45%), Gaps = 41/377 (10%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS 359
Q + L+ + +++ KL+ +T K++++ ++ L L L+ + + LQ +K Q+
Sbjct: 736 QIEKQCSMLDVDLKQSQQKLE-HLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQA 794
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT-------GEVEEIRGNYE------- 405
+ ++ ++++++ L+ + + + LT G++ E++ E
Sbjct: 795 FEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFST 854
Query: 406 ----QALRVKRSVEQQYEESQTRVNELT------VINVNLSSSKAKIEQ-ELAIVAADYD 454
Q +K +E++ E+ ++ EL ++L+ +KA+ EQ ++ Y
Sbjct: 855 LYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYF 914
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVK-IEAVKKSLEIEVKNISVRLEEVE 513
E+T+E + A R ++ T+ HTV L E + K IE +++ E + ++ ++++ E
Sbjct: 915 ELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRR----ENEELTEKMKKAE 970
Query: 514 ANAIVGGKRIISKLEARI-KDMELELDEEKRRHAETIKILRKKERQL------KEVIIQC 566
+ + IS L+A K++ E + + + +I+ +K+ ++ + + +
Sbjct: 971 EEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKK 1030
Query: 567 EEDQKNISL-LQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVA 625
E++ + + L L EK +Q V ++++L + + + Q +L + E +D+
Sbjct: 1031 EKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKE--SDIE 1088
Query: 626 ESNLSLIRAKHRTFVTT 642
+ L+ T V +
Sbjct: 1089 QLRAKLLDLSDSTSVAS 1105
>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1044
Score = 77.0 bits (181), Expect = 2e-13
Identities = 92/485 (18%), Positives = 231/485 (47%), Gaps = 39/485 (8%)
Query: 147 QEIEKELDLYEKEVN-LGSELRQKA-AMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++ EK+L +EV L EL+ K ++ I Q L++ ++ +Q E + + +
Sbjct: 497 EKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELE 556
Query: 205 ASRTLVNRDYTNLSKNVL----AKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
++T + + + L + + + A K C+S E+ + +V E + T V+
Sbjct: 557 DTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVK 616
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
I ++++ KE + + + +++ D + ++ + QL+ + + +T+L+
Sbjct: 617 I-------------EMDQYKEELSKMEKEIMHLKRDGENK-AMHLSQLDMILDQTKTELE 662
Query: 321 SEVTRIKK--KLQIQI-TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ +K+ KLQ TEL +L +LQ + L ++Q D +Q+ Q
Sbjct: 663 KKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKA-Q 721
Query: 378 VTLDQYGVAQRRIQSLTGEVEE----IRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
++L++ I+ LT E+ E I ++ L + ++++++ E + R ++T +++
Sbjct: 722 LSLEE---KYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDM 778
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
+ + ++EQ++ + ++ EL+ +++ + + +L++ E L E++ +++ E
Sbjct: 779 TIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQ 838
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK-DMELELDEEKRRHAETIKIL 552
L+ E++ R++E+E+ + I ++ + I EL L E+ +++ T ++
Sbjct: 839 EISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHT-ELA 897
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-RF 611
+ +Q +Q + + + +S + +++ S++ + LAE+ G S+ + R
Sbjct: 898 EARHQQ-----VQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARM 952
Query: 612 QRELE 616
Q E++
Sbjct: 953 QAEIK 957
Score = 68.1 bits (159), Expect = 9e-11
Identities = 86/433 (19%), Positives = 191/433 (44%), Gaps = 38/433 (8%)
Query: 218 SKNVLAKALMES-KAMNSCDSRVTESITETVRVRETSPTT--C----VVRINTELPAIDN 270
SK + K M+ +A+ + ++V+E ET++VR+ C V+ +N +L
Sbjct: 442 SKGEMKKENMKKDEALKALQNQVSE---ETIKVRQLDSALEICKEELVLHLN-QLEGNKE 497
Query: 271 SYLNQLNELKETVKQFD-DLSV--YILNDSSKQTSI--EIEQLNARVVEAETKLKSEVTR 325
+ QL + E V +L + + L ++S+Q I Q ++++ ET E+
Sbjct: 498 KFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELED 557
Query: 326 IKKKLQIQITELELSLDVANKTNID-LQKTIKKQSLQLTEIQTHYDEV------QRQLQV 378
+ KL+ Q+++LE L +++ + L+K +K E +V RQ+++
Sbjct: 558 TQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKI 617
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS 438
+DQY + + + E+ ++ + E ++ ++++T + + T L
Sbjct: 618 EMDQY---KEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKL 674
Query: 439 KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
+ E EL E ++ + + Q ELK T+ L E ++ + K + +
Sbjct: 675 QHSTETELT-------EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 727
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
+K+++ L E + I K+ + +++ +K+ EL + + +R+ +
Sbjct: 728 YTTIKDLTAELRECKME-IEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGE 786
Query: 559 LKEVIIQCE----EDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+++ II+ E + + + +E + K+ K QL E+E + Q+ + + ++E
Sbjct: 787 MEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKE 846
Query: 615 LEAAEDRADVAES 627
+E + R ES
Sbjct: 847 IERTQQRMKEMES 859
Score = 56.4 bits (130), Expect = 3e-07
Identities = 92/462 (19%), Positives = 203/462 (43%), Gaps = 43/462 (9%)
Query: 143 KKRMQEIEKELDLY-EKEVNLGSELRQ-KAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
+++ + E DL +K + L RQ K M + K + + + +R+ +N+ M+
Sbjct: 588 EEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHL 647
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
++++ T L K A +E K +S ++ +TE++ + V ET +
Sbjct: 648 SQLDM---ILDQTKTELEKKTNAVKELE-KLQHSTETELTEALQKR-EVLETE----LQN 698
Query: 261 INTELPAIDNSYLNQLNELKETVKQFD------DLSVYILNDSSKQTSIEIEQLNARVVE 314
+ EL S L QL EL++ +++ ++ L ++ +EIE ++E
Sbjct: 699 AHGEL----KSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLE 754
Query: 315 AETKLKSEVTRIKKKLQIQITELELSL-----DVANKTNIDLQKTIKKQSLQLTEIQTHY 369
+ LK +K++ Q+T L++++ ++ K I L+ T++K L+L E
Sbjct: 755 MDQALKERNWELKQRAA-QVTHLDMTIREHRGEMEQKI-IKLEGTLEKSELELKECNKQI 812
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
+ + +LQ +Q + + E+ +++ E+ + + +E +E + +
Sbjct: 813 ESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQY 872
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
++L QEL + EL A+ R+Q+VQ + + +E L E E +
Sbjct: 873 KEAIDLG-------QELRLTREQVQNSHTEL--AEARHQQVQAQRE--IERLSSELEDMK 921
Query: 490 KIEAVKKS----LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
++ K + L E+ VR +EA K++ +++E+ + +E+ + H
Sbjct: 922 QLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENH 981
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
A+ ++ ++++ Q E+ + + QD++ Q+V
Sbjct: 982 AKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQV 1023
Score = 48.0 bits (109), Expect = 1e-04
Identities = 66/325 (20%), Positives = 144/325 (44%), Gaps = 26/325 (8%)
Query: 357 KQSLQLTEIQT-HYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR-GNYEQALRVK--- 411
K +++ EIQ H + QL +L +Q + + E E ++ G ++ A VK
Sbjct: 192 KLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQN 251
Query: 412 -RSVEQQYEESQTR----VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADER 466
++ +QYE+ + R + EL + + + + ++ +A + + I +EL
Sbjct: 252 QHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASN 311
Query: 467 YQRVQTELKHTVEHL----HEEQERIV---KIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
++++E+ L + +E+IV I A LE E+ + ++ +E N
Sbjct: 312 SSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTE 371
Query: 520 GKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS 579
++I E + K + LE +H E K + + E QL++ Q +E +K +S+LQ
Sbjct: 372 HEKICLAFE-KAKKIHLE------QHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQD 424
Query: 580 LEKTSQKVSIYKRQLAEQEG-MSQQSVTRVRRFQR-ELEAAEDRADVAESNLSLIRAKHR 637
+ + R L E +G M ++++ + + + + +E+ V + + +L K
Sbjct: 425 IICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEE 484
Query: 638 TFVTTSTVPGSQVYLVQESRALSSE 662
+ + + G++ ++ + S E
Sbjct: 485 LVLHLNQLEGNKEKFEKQLKKKSEE 509
Score = 46.0 bits (104), Expect = 4e-04
Identities = 67/354 (18%), Positives = 147/354 (41%), Gaps = 27/354 (7%)
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKT 354
N+ + I + ++ A K K K+++ QI LE L+ ++ + +KT
Sbjct: 358 NEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKT 417
Query: 355 IKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY-EQALRVKRS 413
+ + Q H + + R L + G ++ ++ ++ E+ ++V+
Sbjct: 418 MSMLQQDIICKQHHLESLDRLL---TESKGEMKKENMKKDEALKALQNQVSEETIKVR-- 472
Query: 414 VEQQYEESQTRVNELTVINVN-LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQT 472
Q + + E V+++N L +K K E++L + + + KEL+I + Q
Sbjct: 473 ---QLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSE 529
Query: 473 E---LKHTVEH----LHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ L+HT++ L +E R ++E + LE +V + L++ ++ +++
Sbjct: 530 QNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEE 589
Query: 526 KLEARIKDMELELDE--EKRRHAETIKI--------LRKKERQLKEVIIQCEEDQKNISL 575
K E+ + +L+ + E A +KI L K E+++ + E ++S
Sbjct: 590 KCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQ 649
Query: 576 LQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
L L++T ++ + E E + + T + ++ E E A L
Sbjct: 650 LDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGEL 703
>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1454
Score = 77.0 bits (181), Expect = 2e-13
Identities = 92/485 (18%), Positives = 231/485 (47%), Gaps = 39/485 (8%)
Query: 147 QEIEKELDLYEKEVN-LGSELRQKA-AMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++ EK+L +EV L EL+ K ++ I Q L++ ++ +Q E + + +
Sbjct: 751 EKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELE 810
Query: 205 ASRTLVNRDYTNLSKNVL----AKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
++T + + + L + + + A K C+S E+ + +V E + T V+
Sbjct: 811 DTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVK 870
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
I ++++ KE + + + +++ D + ++ + QL+ + + +T+L+
Sbjct: 871 I-------------EMDQYKEELSKMEKEIMHLKRDGENK-AMHLSQLDMILDQTKTELE 916
Query: 321 SEVTRIKK--KLQIQI-TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ +K+ KLQ TEL +L +LQ + L ++Q D +Q+ Q
Sbjct: 917 KKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKA-Q 975
Query: 378 VTLDQYGVAQRRIQSLTGEVEE----IRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
++L++ I+ LT E+ E I ++ L + ++++++ E + R ++T +++
Sbjct: 976 LSLEE---KYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDM 1032
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
+ + ++EQ++ + ++ EL+ +++ + + +L++ E L E++ +++ E
Sbjct: 1033 TIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQ 1092
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK-DMELELDEEKRRHAETIKIL 552
L+ E++ R++E+E+ + I ++ + I EL L E+ +++ T ++
Sbjct: 1093 EISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHT-ELA 1151
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-RF 611
+ +Q +Q + + + +S + +++ S++ + LAE+ G S+ + R
Sbjct: 1152 EARHQQ-----VQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARM 1206
Query: 612 QRELE 616
Q E++
Sbjct: 1207 QAEIK 1211
Score = 68.1 bits (159), Expect = 9e-11
Identities = 86/433 (19%), Positives = 191/433 (44%), Gaps = 38/433 (8%)
Query: 218 SKNVLAKALMES-KAMNSCDSRVTESITETVRVRETSPTT--C----VVRINTELPAIDN 270
SK + K M+ +A+ + ++V+E ET++VR+ C V+ +N +L
Sbjct: 696 SKGEMKKENMKKDEALKALQNQVSE---ETIKVRQLDSALEICKEELVLHLN-QLEGNKE 751
Query: 271 SYLNQLNELKETVKQFD-DLSV--YILNDSSKQTSI--EIEQLNARVVEAETKLKSEVTR 325
+ QL + E V +L + + L ++S+Q I Q ++++ ET E+
Sbjct: 752 KFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELED 811
Query: 326 IKKKLQIQITELELSLDVANKTNID-LQKTIKKQSLQLTEIQTHYDEV------QRQLQV 378
+ KL+ Q+++LE L +++ + L+K +K E +V RQ+++
Sbjct: 812 TQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKI 871
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS 438
+DQY + + + E+ ++ + E ++ ++++T + + T L
Sbjct: 872 EMDQY---KEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKL 928
Query: 439 KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
+ E EL E ++ + + Q ELK T+ L E ++ + K + +
Sbjct: 929 QHSTETELT-------EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 981
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
+K+++ L E + I K+ + +++ +K+ EL + + +R+ +
Sbjct: 982 YTTIKDLTAELRECKME-IEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGE 1040
Query: 559 LKEVIIQCE----EDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+++ II+ E + + + +E + K+ K QL E+E + Q+ + + ++E
Sbjct: 1041 MEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKE 1100
Query: 615 LEAAEDRADVAES 627
+E + R ES
Sbjct: 1101 IERTQQRMKEMES 1113
Score = 58.0 bits (134), Expect = 1e-07
Identities = 96/499 (19%), Positives = 213/499 (42%), Gaps = 43/499 (8%)
Query: 143 KKRMQEIEKELDLY-EKEVNLGSELRQ-KAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
+++ + E DL +K + L RQ K M + K + + + +R+ +N+ M+
Sbjct: 842 EEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHL 901
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
++++ T L K A +E K +S ++ +TE++ + V ET +
Sbjct: 902 SQLDM---ILDQTKTELEKKTNAVKELE-KLQHSTETELTEALQKR-EVLETE----LQN 952
Query: 261 INTELPAIDNSYLNQLNELKETVKQFD------DLSVYILNDSSKQTSIEIEQLNARVVE 314
+ EL S L QL EL++ +++ ++ L ++ +EIE ++E
Sbjct: 953 AHGEL----KSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLE 1008
Query: 315 AETKLKSEVTRIKKKLQIQITELELSL-----DVANKTNIDLQKTIKKQSLQLTEIQTHY 369
+ LK +K++ Q+T L++++ ++ K I L+ T++K L+L E
Sbjct: 1009 MDQALKERNWELKQRAA-QVTHLDMTIREHRGEMEQKI-IKLEGTLEKSELELKECNKQI 1066
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
+ + +LQ +Q + + E+ +++ E+ + + +E +E + +
Sbjct: 1067 ESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQY 1126
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
++L QEL + EL A+ R+Q+VQ + + +E L E E +
Sbjct: 1127 KEAIDLG-------QELRLTREQVQNSHTEL--AEARHQQVQAQRE--IERLSSELEDMK 1175
Query: 490 KIEAVKKS----LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
++ K + L E+ VR +EA K++ +++E+ + +E+ + H
Sbjct: 1176 QLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENH 1235
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
A+ ++ ++++ Q E+ + + QD++ Q+V +
Sbjct: 1236 AKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKE 1295
Query: 606 TRVRRFQRELEAAEDRADV 624
+ + R Q ++ E D+
Sbjct: 1296 SELTRLQAKISGHEKAEDI 1314
Score = 50.8 bits (116), Expect = 2e-05
Identities = 100/529 (18%), Positives = 219/529 (41%), Gaps = 43/529 (8%)
Query: 165 ELRQKAAMYRGKSAKAIAQTLLEES--RRNVQNERMYKPDFQASRTLVNRDYTNLSKNVL 222
EL + Y+ K A+ + + EE RN+ N Q L + L + +
Sbjct: 247 ELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKL- 305
Query: 223 AKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDN------SYLNQL 276
+ L E R+ V + T ++++ +EL D S +N+
Sbjct: 306 -RQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNEN 364
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL-QIQIT 335
ELK V ++ + + + + +E+ L + ++ LK E+ K L + Q++
Sbjct: 365 RELKVRVAAQNE-RLDLCQQEIESSRVELRSLEKII--SQLPLKRELFGFKSYLSKYQMS 421
Query: 336 ELELSLD----VANKTNIDLQKTIKKQSLQLTEIQT-HYDEVQRQLQVTLDQYGVAQR-- 388
D + + + K +++ EIQ H + QL +L +Q
Sbjct: 422 SFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESS 481
Query: 389 RIQSLTGEVEEIRGNYEQALRVKR--SVEQQYEESQTR----VNELTVINVNLSSSKAKI 442
++ SL E ++ G+ ++++ + ++ +QYE+ + R + EL + + + + +
Sbjct: 482 KLSSLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDL 541
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL----HEEQERIV---KIEAVK 495
+ +A + + I +EL ++++E+ L + +E+IV I A
Sbjct: 542 KVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKN 601
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
LE E+ + ++ +E N ++I E + K + LE +H E K + +
Sbjct: 602 AELEQELMEKNEKIRSLETNINTEHEKICLAFE-KAKKIHLE------QHKEMEKQIERL 654
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG-MSQQSVTRVRRFQR- 613
E QL++ Q +E +K +S+LQ + + R L E +G M ++++ + +
Sbjct: 655 EAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKAL 714
Query: 614 ELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSE 662
+ + +E+ V + + +L K + + + G++ ++ + S E
Sbjct: 715 QNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEE 763
Score = 36.3 bits (80), Expect = 0.35
Identities = 42/184 (22%), Positives = 81/184 (44%), Gaps = 9/184 (4%)
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI-EAVKKSLEIE 501
+Q +V ++ +TK I ++ Q+ K ++ ++Q V I E +LE E
Sbjct: 125 QQNACLVTQNHSLMTKFESI---HFELTQSRAKVSMLESAQQQAASVPILEEQIINLEAE 181
Query: 502 VKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKE 561
V L E E N + ++++ + E +++ + E + K E K ++ ERQ E
Sbjct: 182 VSAQDKVLREAE-NKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNE 240
Query: 562 VIIQCEEDQKNI----SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
+ EE K + + LEK + I +R L E +++ R ++ ELE
Sbjct: 241 ALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEI 300
Query: 618 AEDR 621
+++
Sbjct: 301 LKEK 304
Score = 31.9 bits (69), Expect = 7.5
Identities = 32/143 (22%), Positives = 66/143 (46%), Gaps = 10/143 (6%)
Query: 524 ISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
I LEA + + L E + + ++ K++ +KE+ L+E +C I L D LE+T
Sbjct: 175 IINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEEC------IKLKVDLLEQT 228
Query: 584 SQKVSIYKRQ---LAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFV 640
Q +++ L E +S+ ++ +LE + ++ E NL+ +++
Sbjct: 229 KQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQ 288
Query: 641 TTSTVPGSQVYLVQES-RALSSE 662
+ S++ +++E R L E
Sbjct: 289 ERCGLYKSELEILKEKLRQLKEE 311
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 76.6 bits (180), Expect = 3e-13
Identities = 103/473 (21%), Positives = 214/473 (45%), Gaps = 41/473 (8%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
QE EL+L ++ S + + R + + +ES+ +++ + + +
Sbjct: 1302 QETMNELELLTEQ----STTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTI 1357
Query: 207 RTLVNRDYTNLSKNV---LAKALMESKAMNSCDSRVTESITETVRV----RETSPT-TCV 258
+ + + L +++ LAK + ES++ + E ET ++ + P + +
Sbjct: 1358 KEALEVKHDQLKEHIRETLAK-IQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSAL 1416
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLS--VYILNDSSKQTSIEIEQLNARVVEAE 316
+RI E+ + +E+K K+ DDL +L S Q I+++ A+ +E E
Sbjct: 1417 LRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETE 1476
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE-IQTHYDEV-QR 374
+LK +K++ + I EL ++L +T I TI+KQ + + +Q E+ ++
Sbjct: 1477 EELKVAHCCLKEQ-EETINELRVNLS-EKETEI---STIQKQLEAINDKLQNKIQEIYEK 1531
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL---TVI 431
+ Q+ + Q Q + L + +E R + AL +S+E + E R+ E I
Sbjct: 1532 EEQLNIKQISEVQENVNELK-QFKEHRKAKDSAL---QSIESKMLELTNRLQESQEEIQI 1587
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE-LKHTVEHLHEEQERIVK 490
+ ++++ L I E TKE+ + Q + + LK T ++E QE++ +
Sbjct: 1588 MIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTA--VNETQEKMCE 1645
Query: 491 IEAVKKSLEIEVKNI-SVRLEEVEANAIVGGK----RIISKLEARIKDME----LELDEE 541
IE +K+ E + N+ ++ E + I+ R ++K ++ +E +E D+
Sbjct: 1646 IEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQL 1705
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
K ETI +K+ +LK V + +E Q+ I L+ + + + ++S ++ L
Sbjct: 1706 KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDL 1758
Score = 72.1 bits (169), Expect = 6e-12
Identities = 96/486 (19%), Positives = 228/486 (46%), Gaps = 58/486 (11%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNV--QNERMYK 200
+ +M E+ L ++E+ + +++K M R + A I + L+E+ + + + + +
Sbjct: 1568 ESKMLELTNRLQESQEEIQI--MIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQE 1625
Query: 201 PDFQASR-TLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRET-SPTTCV 258
++Q + T VN + + K E++ +N ++ TE+I T + E V
Sbjct: 1626 KEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLN-LENIETENIRLTQILHENLEEMRSV 1684
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARV-VEAET 317
+ +L +++ + + ++LKE +++ I D KQ ++I ++ + E
Sbjct: 1685 TKERDDLRSVEETLKVERDQLKENLRET------ITRDLEKQEELKIVHMHLKEHQETID 1738
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL+ V+ ++ +LE S D ++ +Q+ ++ + L E Q D+++ +
Sbjct: 1739 KLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVS 1798
Query: 378 VTLDQYGVAQRRIQS----LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
D+ Q+ +++ L +++E++ N Q + +K+ V E+Q +V+E+ +
Sbjct: 1799 EKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVN----ETQKKVSEMEQLKK 1854
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
+ +Q L + + + L +A E ++ ++ E+K ++ E++ + ++E
Sbjct: 1855 QIK------DQSLTLSKLEIEN----LNLAQELHENLE-EMKSVMK----ERDNLRRVE- 1898
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILR 553
++L++E + L+E +A + +++ +K + L +E H ET+ LR
Sbjct: 1899 --ETLKLERDQLKESLQETKARDL--------EIQQELKTARM-LSKE---HKETVDKLR 1944
Query: 554 KKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL---AEQEGMSQQSVTRVRR 610
+K + E IQ + QK++ +D L+K Q++ + QL E MS + + + +
Sbjct: 1945 EK---ISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQ 2001
Query: 611 FQRELE 616
+++ E
Sbjct: 2002 LKKQFE 2007
Score = 66.9 bits (156), Expect = 2e-10
Identities = 103/507 (20%), Positives = 230/507 (45%), Gaps = 51/507 (10%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTL--LEESRRNVQNER-MY 199
K++++ + L E+E L +E Q+ + K + Q L++ + ++Q ER
Sbjct: 893 KEQLENRDSPLQTVEREKTLITEKLQQTL----EEVKTLTQEKDDLKQLQESLQIERDQL 948
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
K D + + N D +N L + +N+ S+++E ++ + + E + T
Sbjct: 949 KSDIHDTVNM-NIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGET-KD 1006
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ ID Q E K T D+ + + ++ I++ N E + L
Sbjct: 1007 EFQQKMVGIDKK---QDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKN----ELQQML 1059
Query: 320 KSEVTRIKKKLQIQITE-LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+S + K++L+ + E +E++++ + + L +KKQ + + + H + + +L
Sbjct: 1060 ESVIAE-KEQLKTDLKENIEMTIENQEELRL-LGDELKKQQEIVAQEKNHAIKKEGELSR 1117
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS 438
T D+ + +++ + +++E +Q L +V+++ E Q ++NE+ + L +
Sbjct: 1118 TCDRLAEVEEKLKEKSQQLQE---KQQQLL----NVQEEMSEMQKKINEIENLKNELKNK 1170
Query: 439 KAKIEQ------ELAI-VAADYDE---ITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+ +E ELA + +Y+E ITKE ++ E + +TE H ++ E
Sbjct: 1171 ELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIRE----- 1225
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
IEA + E+K + L+E I +R +S+ A+I + + +L++ + E
Sbjct: 1226 --IEATGLQTKEELKIAHIHLKE-HQETIDELRRSVSEKTAQIINTQ-DLEKSHTKLQEE 1281
Query: 549 IKILRKKERQLKEV--IIQCEEDQKNISLL-QDSLEK---TSQKVSIYKRQLAEQEGMSQ 602
I +L +++ L V + + +E + LL + S K T ++ + + +L E+ SQ
Sbjct: 1282 IPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQ 1341
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNL 629
+ + + + + L+ ++ +V L
Sbjct: 1342 EEIKSLTKERDNLKTIKEALEVKHDQL 1368
Score = 66.1 bits (154), Expect = 4e-10
Identities = 101/474 (21%), Positives = 201/474 (42%), Gaps = 36/474 (7%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNV---LAKALM---ESKAMNSCDSRV 239
L+ES +++ K D Q + ++ + L +N+ +AK L E K + C
Sbjct: 1430 LQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQ 1489
Query: 240 TESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK 299
E+I E +RV + T + I +L AI++ N++ E+ E +Q + + + ++
Sbjct: 1490 EETINE-LRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQENVN 1548
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS 359
+ E A+ A ++S++ + +LQ E+++ + + +Q+ ++ +
Sbjct: 1549 ELKQFKEHRKAKD-SALQSIESKMLELTNRLQESQEEIQIMIKEKEEMK-RVQEALQIER 1606
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQY--GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ 417
QL E ++ Q Q+ A Q E+E ++ +E K ++E
Sbjct: 1607 DQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQ---KLNLEN- 1662
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVA----ADYDEITKELRIADERYQRVQTE 473
E R+ ++ N+ S K +L V + D++ + LR R Q E
Sbjct: 1663 IETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEE 1722
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
LK HL E QE I K+ + E+ N+ LE +N + + + + E RI
Sbjct: 1723 LKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLE--HSNDALKAQDLKIQEELRIAH 1780
Query: 534 MELE------------LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
M L+ + E+ + + K L +L+E I + + ++ + L+ +
Sbjct: 1781 MHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVN 1840
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAK 635
+T +KVS QL +Q + QS+T + L A++ + E S+++ +
Sbjct: 1841 ETQKKVS-EMEQLKKQ--IKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKER 1891
Score = 64.1 bits (149), Expect = 2e-09
Identities = 66/336 (19%), Positives = 159/336 (47%), Gaps = 20/336 (5%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL-ELSLDVANKTNIDLQKTIKK 357
K ++ EQ V+E ++ E+ + K+ Q + L L +++ KT +LQ+ ++
Sbjct: 823 KTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQ-ELQEKTRE 881
Query: 358 QSLQLTEIQTHYDEVQRQ---LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
+L E++ ++++ + LQ + + ++Q EV+ + + +++ S+
Sbjct: 882 VQERLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESL 941
Query: 415 EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEI-TKELRIADERYQRVQTE 473
+ + ++ ++ +++ +N+N+ + + ++ L + + I T + +I++E + + E
Sbjct: 942 QIERDQLKSDIHD--TVNMNIDTQE-QLRNALESLKQHQETINTLKSKISEEVSRNLHME 998
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
++T E E Q+++V I+ K ++E KN +V+ N I+ +R I L +
Sbjct: 999 -ENTGETKDEFQQKMVGID---KKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNE 1054
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
++ L+ I + + LKE I E+Q+ + LL D L+K + V+ K
Sbjct: 1055 LQQMLES-------VIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNH 1107
Query: 594 LAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
++EG ++ R+ + +L+ + + L
Sbjct: 1108 AIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL 1143
Score = 58.4 bits (135), Expect = 8e-08
Identities = 73/385 (18%), Positives = 179/385 (46%), Gaps = 32/385 (8%)
Query: 275 QLNELKETVKQFD-DLSVYILN-DSSKQTSIEIEQLNARVVEAETKLKSEVT-RIKKKLQ 331
++ EL T KQ + D+ +Y ++ K+ +++E+ TKL S + ++ K L
Sbjct: 654 KMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLL 713
Query: 332 IQITELELSL-DVANKTNIDLQKT--IKKQSLQLTEIQTHYDEVQR---QLQVTLDQYGV 385
+ ELE + D+ + N ++++ ++++ + L+E+++ EV+R ++Q ++ +
Sbjct: 714 CNL-ELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHI 772
Query: 386 AQRRIQSLTGEV----EEIRGNYEQALRVK---RSVEQQYEESQTRVNELTVINVNLSSS 438
L EV ++G E+ + K + + Y+ + ++++
Sbjct: 773 ITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQK 832
Query: 439 KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE----QERIVKIEAV 494
+ +E + + ++KE + D ++TEL + + L E+ QER+ ++E +
Sbjct: 833 YKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQL 892
Query: 495 KKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRK 554
K+ LE N L+ VE + +++ LE +K + E D+ K+ E+++I R
Sbjct: 893 KEQLE----NRDSPLQTVEREKTLITEKLQQTLE-EVKTLTQEKDDLKQLQ-ESLQIERD 946
Query: 555 K-ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG----MSQQSVTRVR 609
+ + + + + + Q+ + +SL++ + ++ K +++E+ M + +
Sbjct: 947 QLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKD 1006
Query: 610 RFQRELEAAEDRADVAESNLSLIRA 634
FQ+++ + + D+ N + A
Sbjct: 1007 EFQQKMVGIDKKQDLEAKNTQTLTA 1031
Score = 38.7 bits (86), Expect = 0.065
Identities = 98/464 (21%), Positives = 210/464 (45%), Gaps = 31/464 (6%)
Query: 181 IAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVT 240
IA L+E + + R + + + +D N S L + + E KA +
Sbjct: 1778 IAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLEN-SNAKLQEKIQELKANEHQLITLK 1836
Query: 241 ESITETVR-VRETSPTTCVVRINT-ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSS 298
+ + ET + V E ++ + L ++ LN EL E +++ SV D+
Sbjct: 1837 KDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMK--SVMKERDNL 1894
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNID-LQKTIKK 357
++ ++ ++ E+ + K+ I+++L+ T LS + +K +D L++ I +
Sbjct: 1895 RRVEETLKLERDQLKESLQETKARDLEIQQELK---TARMLSKE--HKETVDKLREKISE 1949
Query: 358 QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ 417
+++Q+++IQ D+ + +LQ + + + ++ +Q L V+E + + +++Q
Sbjct: 1950 KTIQISDIQKDLDKSKDELQKKIQE--LQKKELQLL--RVKEDVNMSHKKINEMEQLKKQ 2005
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK-ELRIADERYQRVQTELKH 476
+E + E+ N L+ + +E+ IVA + DE+ + + + ER Q + T L+
Sbjct: 2006 FEPNYLCKCEMD--NFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIAT-LRE 2062
Query: 477 TVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM-E 535
+ + Q VK E K+ L +++ L E + + I + S+++ + +
Sbjct: 2063 MI--ARDRQNHQVKPE--KRLLSDGQQHLMESLRE-KCSRIKELLKRYSEMDDHYECLNR 2117
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQ-DSLEKT-SQKVSIYKRQ 593
L LD EK E +I++K + L V EE + I+ + D +++ QK + K Q
Sbjct: 2118 LSLDLEK--EIEFHRIMKKLKYVLSYVTKIKEEQHECINKFEMDFIDEVEKQKELLIKIQ 2175
Query: 594 LAEQE-GMSQQSVTRVRRFQR-ELEAAEDRADVAESNLSLIRAK 635
+Q+ + + + ++ Q +L E D +ES I+ +
Sbjct: 2176 HLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTE 2219
Score = 32.3 bits (70), Expect = 5.6
Identities = 52/287 (18%), Positives = 120/287 (41%), Gaps = 16/287 (5%)
Query: 282 TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSL 341
T QF + Y+ N E L R + LK ++ + + + Q E +
Sbjct: 318 TALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLA 377
Query: 342 DVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
+ + ++ LQK ++ LT + + Q ++ + +RR+ G++ +++
Sbjct: 378 QLLEEKDL-LQKVQNEKIENLTRMLVTSSSLTLQQELKAKR----KRRVTWCLGKINKMK 432
Query: 402 G-NYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA-DYDEITKE 459
NY + ++ + + +N L I+ ++ S L ++ +++ TK
Sbjct: 433 NSNYADQFNIPTNITTKTHKLS--INLLREIDESVCSESDVFSNTLDTLSEIEWNPATKL 490
Query: 460 LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVG 519
L E + L+ ++L + E++ + E + L+++ KN E +E
Sbjct: 491 LN--QENIESELNSLRADYDNLVLDYEQL-RTEKEEMELKLKEKNDLDEFEALERKTKKD 547
Query: 520 GK----RIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ IS L+ +K E+ + + + +++LR+KE Q+K++
Sbjct: 548 QEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKEDQIKKL 594
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 76.6 bits (180), Expect = 3e-13
Identities = 103/473 (21%), Positives = 214/473 (45%), Gaps = 41/473 (8%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
QE EL+L ++ S + + R + + +ES+ +++ + + +
Sbjct: 1282 QETMNELELLTEQ----STTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTI 1337
Query: 207 RTLVNRDYTNLSKNV---LAKALMESKAMNSCDSRVTESITETVRV----RETSPT-TCV 258
+ + + L +++ LAK + ES++ + E ET ++ + P + +
Sbjct: 1338 KEALEVKHDQLKEHIRETLAK-IQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSAL 1396
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLS--VYILNDSSKQTSIEIEQLNARVVEAE 316
+RI E+ + +E+K K+ DDL +L S Q I+++ A+ +E E
Sbjct: 1397 LRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETE 1456
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE-IQTHYDEV-QR 374
+LK +K++ + I EL ++L +T I TI+KQ + + +Q E+ ++
Sbjct: 1457 EELKVAHCCLKEQ-EETINELRVNLS-EKETEI---STIQKQLEAINDKLQNKIQEIYEK 1511
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL---TVI 431
+ Q + Q Q ++ L + +E R + AL +S+E + E R+ E I
Sbjct: 1512 EEQFNIKQISEVQEKVNELK-QFKEHRKAKDSAL---QSIESKMLELTNRLQESQEEIQI 1567
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE-LKHTVEHLHEEQERIVK 490
+ ++++ L I E TKE+ + Q + + LK T ++E QE++ +
Sbjct: 1568 MIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTA--VNETQEKMCE 1625
Query: 491 IEAVKKSLEIEVKNI-SVRLEEVEANAIVGGK----RIISKLEARIKDME----LELDEE 541
IE +K+ E + N+ ++ E + I+ R ++K ++ +E +E D+
Sbjct: 1626 IEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQL 1685
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
K ETI +K+ +LK V + +E Q+ I L+ + + + ++S ++ L
Sbjct: 1686 KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDL 1738
Score = 68.1 bits (159), Expect = 9e-11
Identities = 102/478 (21%), Positives = 202/478 (42%), Gaps = 37/478 (7%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNV---LAKALM---ESKAMNSCDSRV 239
L+ES +++ K D Q + ++ + L +N+ +AK L E K + C
Sbjct: 1410 LQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQ 1469
Query: 240 TESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK 299
E+I E +RV + T + I +L AI++ N++ E+ E +QF+ + + +
Sbjct: 1470 EETINE-LRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVN 1528
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS 359
+ E A+ A ++S++ + +LQ E+++ + + +Q+ ++ +
Sbjct: 1529 ELKQFKEHRKAKD-SALQSIESKMLELTNRLQESQEEIQIMIKEKEEMK-RVQEALQIER 1586
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQY--GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ 417
QL E ++ Q Q+ A Q E+E ++ +E K ++E
Sbjct: 1587 DQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQ---KLNLEN- 1642
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVA----ADYDEITKELRIADERYQRVQTE 473
E R+ ++ N+ S K +L V + D++ + LR R Q E
Sbjct: 1643 IETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEE 1702
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
LK HL E QE I K+ + E+ N+ LE +N + + + + E RI
Sbjct: 1703 LKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLE--HSNDALKAQDLKIQEELRIAH 1760
Query: 534 MELE------------LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
M L+ + E+ + + K L +L+E I + + ++ + L+ +
Sbjct: 1761 MHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVN 1820
Query: 582 KTSQKVS---IYKRQLAEQE-GMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAK 635
+T +KVS K+Q+ +Q +S+ + + Q+ E E+ V + +L R +
Sbjct: 1821 ETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVE 1878
Score = 66.9 bits (156), Expect = 2e-10
Identities = 103/507 (20%), Positives = 230/507 (45%), Gaps = 51/507 (10%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTL--LEESRRNVQNER-MY 199
K++++ + L E+E L +E Q+ + K + Q L++ + ++Q ER
Sbjct: 873 KEQLENRDSTLQTVEREKTLITEKLQQTL----EEVKTLTQEKDDLKQLQESLQIERDQL 928
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
K D + + N D +N L + +N+ S+++E ++ + + E + T
Sbjct: 929 KSDIHDTVNM-NIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGET-KD 986
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ ID Q E K T D+ + + ++ I++ N E + L
Sbjct: 987 EFQQKMVGIDKK---QDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKN----ELQQML 1039
Query: 320 KSEVTRIKKKLQIQITE-LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+S + K++L+ + E +E++++ + + L +KKQ + + + H + + +L
Sbjct: 1040 ESVIAE-KEQLKTDLKENIEMTIENQEELRL-LGDELKKQQEIVAQEKNHAIKKEGELSR 1097
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS 438
T D+ + +++ + +++E +Q L +V+++ E Q ++NE+ + L +
Sbjct: 1098 TCDRLAEVEEKLKEKSQQLQE---KQQQLL----NVQEEMSEMQKKINEIENLKNELKNK 1150
Query: 439 KAKIEQ------ELAI-VAADYDE---ITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+ +E ELA + +Y+E ITKE ++ E + +TE H ++ E
Sbjct: 1151 ELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIRE----- 1205
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
IEA + E+K + L+E I +R +S+ A+I + + +L++ + E
Sbjct: 1206 --IEATGLQTKEELKIAHIHLKE-HQETIDELRRSVSEKTAQIINTQ-DLEKSHTKLQEE 1261
Query: 549 IKILRKKERQLKEV--IIQCEEDQKNISLL-QDSLEK---TSQKVSIYKRQLAEQEGMSQ 602
I +L +++ L V + + +E + LL + S K T ++ + + +L E+ SQ
Sbjct: 1262 IPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQ 1321
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNL 629
+ + + + + L+ ++ +V L
Sbjct: 1322 EEIKSLTKERDNLKTIKEALEVKHDQL 1348
Score = 64.1 bits (149), Expect = 2e-09
Identities = 66/336 (19%), Positives = 159/336 (47%), Gaps = 20/336 (5%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL-ELSLDVANKTNIDLQKTIKK 357
K ++ EQ V+E ++ E+ + K+ Q + L L +++ KT +LQ+ ++
Sbjct: 803 KTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQ-ELQEKTRE 861
Query: 358 QSLQLTEIQTHYDEVQRQ---LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
+L E++ ++++ + LQ + + ++Q EV+ + + +++ S+
Sbjct: 862 VQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESL 921
Query: 415 EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEI-TKELRIADERYQRVQTE 473
+ + ++ ++ +++ +N+N+ + + ++ L + + I T + +I++E + + E
Sbjct: 922 QIERDQLKSDIHD--TVNMNIDTQE-QLRNALESLKQHQETINTLKSKISEEVSRNLHME 978
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
++T E E Q+++V I+ K ++E KN +V+ N I+ +R I L +
Sbjct: 979 -ENTGETKDEFQQKMVGID---KKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNE 1034
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
++ L+ I + + LKE I E+Q+ + LL D L+K + V+ K
Sbjct: 1035 LQQMLES-------VIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNH 1087
Query: 594 LAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
++EG ++ R+ + +L+ + + L
Sbjct: 1088 AIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL 1123
Score = 58.8 bits (136), Expect = 6e-08
Identities = 73/385 (18%), Positives = 179/385 (46%), Gaps = 32/385 (8%)
Query: 275 QLNELKETVKQFD-DLSVYILN-DSSKQTSIEIEQLNARVVEAETKLKSEVT-RIKKKLQ 331
++ EL T KQ + D+ +Y ++ K+ +++E+ TKL S + ++ K L
Sbjct: 634 KMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLL 693
Query: 332 IQITELELSL-DVANKTNIDLQKT--IKKQSLQLTEIQTHYDEVQR---QLQVTLDQYGV 385
+ ELE + D+ + N ++++ ++++ + L+E+++ EV+R ++Q ++ +
Sbjct: 694 CNL-ELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHI 752
Query: 386 AQRRIQSLTGEV----EEIRGNYEQALRVK---RSVEQQYEESQTRVNELTVINVNLSSS 438
L EV ++G E+ + K + + Y+ + ++++
Sbjct: 753 ITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQK 812
Query: 439 KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE----QERIVKIEAV 494
+ +E + + ++KE + D ++TEL + + L E+ QER+ ++E +
Sbjct: 813 YKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQL 872
Query: 495 KKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRK 554
K+ LE N L+ VE + +++ LE +K + E D+ K+ E+++I R
Sbjct: 873 KEQLE----NRDSTLQTVEREKTLITEKLQQTLE-EVKTLTQEKDDLKQLQ-ESLQIERD 926
Query: 555 K-ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG----MSQQSVTRVR 609
+ + + + + + Q+ + +SL++ + ++ K +++E+ M + +
Sbjct: 927 QLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKD 986
Query: 610 RFQRELEAAEDRADVAESNLSLIRA 634
FQ+++ + + D+ N + A
Sbjct: 987 EFQQKMVGIDKKQDLEAKNTQTLTA 1011
Score = 39.5 bits (88), Expect = 0.037
Identities = 78/385 (20%), Positives = 167/385 (43%), Gaps = 34/385 (8%)
Query: 279 LKETVKQFDDLSVYILNDSSKQTSIE--IEQLNARVVEAETKLKS-EVTRIKKKLQIQIT 335
LKE + D L + + K ++++ +E NA++ E +LK+ E I K + T
Sbjct: 1763 LKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET 1822
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+ ++S L+K IK QSL L++++ + ++L L++ + +L
Sbjct: 1823 QKKVS------EMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRR 1876
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
E ++ +Q + + + E Q + +++ + K+ ++++ +
Sbjct: 1877 VEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISD 1936
Query: 456 ITKELRIADERYQRVQTELKHTV-----------EHLHEE-QERIVKI-EAVKKSLEIE- 501
I K+L + + Q+ Q H V +HL E +E+ +I E +K+ E++
Sbjct: 1937 IQKDLDKSKDELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDD 1996
Query: 502 ----VKNISVRLE---EVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRK 554
+ +S+ LE E + + K +S + K +E +R E +I++K
Sbjct: 1997 HYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKK 2056
Query: 555 KERQLKEVIIQCEEDQKNISLLQ-DSLEKT-SQKVSIYKRQLAEQE-GMSQQSVTRVRRF 611
+ L V EE ++I+ + D +++ QK + K Q +Q+ + + + ++
Sbjct: 2057 LKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLN 2116
Query: 612 QR-ELEAAEDRADVAESNLSLIRAK 635
Q +L E D +ES I+ +
Sbjct: 2117 QNMDLHIEEILKDFSESEFPSIKTE 2141
>AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransferase
9 protein.
Length = 978
Score = 74.5 bits (175), Expect = 1e-12
Identities = 91/485 (18%), Positives = 230/485 (47%), Gaps = 39/485 (8%)
Query: 147 QEIEKELDLYEKEVN-LGSELRQKA-AMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++ EK+L +EV L EL+ K ++ I Q L++ ++ +Q E + + +
Sbjct: 431 EKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELE 490
Query: 205 ASRTLVNRDYTNLSKNVL----AKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
++T + + + L + + + A K C+S E+ + +V E + T V+
Sbjct: 491 DTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVK 550
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
I ++++ KE + + + +++ D + ++ QL+ + + +T+L+
Sbjct: 551 I-------------EMDQYKEELSKMEKEIMHLKRDGENK-AMHFSQLDMILDQTKTELE 596
Query: 321 SEVTRIKK--KLQIQI-TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ +K+ KLQ TEL +L +LQ + L ++Q D +Q+ Q
Sbjct: 597 KKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKA-Q 655
Query: 378 VTLDQYGVAQRRIQSLTGEVEE----IRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
++L++ I+ LT E+ E I ++ L + ++++++ E + R ++T +++
Sbjct: 656 LSLEE---KYTTIKDLTAELRECKMEIEDEKQELLEMDQALKERNWELKQRAAQVTHLDM 712
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
+ + ++EQ++ + ++ EL+ +++ + + +L++ E L E++ +++ E
Sbjct: 713 TIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQ 772
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK-DMELELDEEKRRHAETIKIL 552
L+ E++ R++E+E+ + I ++ + I +L L E+ +++ T ++
Sbjct: 773 EISQLKKEIERTQQRMKEMESVMKEQEQYIATQCKEAIDLGQKLRLTREQVQNSHT-ELA 831
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-RF 611
+ +Q +Q + + + +S + +++ S++ + LAE+ G S+ + R
Sbjct: 832 EARHQQ-----VQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARM 886
Query: 612 QRELE 616
Q E++
Sbjct: 887 QAEIK 891
Score = 67.7 bits (158), Expect = 1e-10
Identities = 86/433 (19%), Positives = 191/433 (44%), Gaps = 38/433 (8%)
Query: 218 SKNVLAKALMES-KAMNSCDSRVTESITETVRVRETSPTT--C----VVRINTELPAIDN 270
SK + K M+ +A+ + ++V+E ET++VR+ C V+ +N +L
Sbjct: 376 SKGEMKKENMKKDEALKALQNQVSE---ETIKVRQLDSALEICKEELVLHLN-QLEGNKE 431
Query: 271 SYLNQLNELKETVKQFD-DLSV--YILNDSSKQTSI--EIEQLNARVVEAETKLKSEVTR 325
+ QL + E V +L + + L ++S+Q I Q ++++ ET E+
Sbjct: 432 KFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELED 491
Query: 326 IKKKLQIQITELELSLDVANKTNID-LQKTIKKQSLQLTEIQTHYDEV------QRQLQV 378
+ KL+ Q+++LE L +++ + L+K +K E +V RQ+++
Sbjct: 492 TQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKI 551
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS 438
+DQY + + + E+ ++ + E ++ ++++T + + T L
Sbjct: 552 EMDQY---KEELSKMEKEIMHLKRDGENKAMHFSQLDMILDQTKTELEKKTNAVKELEKL 608
Query: 439 KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
+ E EL E ++ + + Q ELK T+ L E ++ + K + +
Sbjct: 609 QHSTETELT-------EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 661
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
+K+++ L E + I K+ + +++ +K+ EL + + +R+ +
Sbjct: 662 YTTIKDLTAELRECKME-IEDEKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGE 720
Query: 559 LKEVIIQCE----EDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+++ II+ E + + + +E + K+ K QL E+E + Q+ + + ++E
Sbjct: 721 MEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKE 780
Query: 615 LEAAEDRADVAES 627
+E + R ES
Sbjct: 781 IERTQQRMKEMES 793
Score = 56.4 bits (130), Expect = 3e-07
Identities = 92/462 (19%), Positives = 204/462 (44%), Gaps = 43/462 (9%)
Query: 143 KKRMQEIEKELDLY-EKEVNLGSELRQ-KAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
+++ + E DL +K + L RQ K M + K + + + +R+ +N+ M+
Sbjct: 522 EEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMH- 580
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
F ++++ T L K A +E K +S ++ +TE++ + V ET +
Sbjct: 581 --FSQLDMILDQTKTELEKKTNAVKELE-KLQHSTETELTEALQKR-EVLETE----LQN 632
Query: 261 INTELPAIDNSYLNQLNELKETVKQFD------DLSVYILNDSSKQTSIEIEQLNARVVE 314
+ EL S L QL EL++ +++ ++ L ++ +EIE ++E
Sbjct: 633 AHGEL----KSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDEKQELLE 688
Query: 315 AETKLKSEVTRIKKKLQIQITELELSL-----DVANKTNIDLQKTIKKQSLQLTEIQTHY 369
+ LK +K++ Q+T L++++ ++ K I L+ T++K L+L E
Sbjct: 689 MDQALKERNWELKQRAA-QVTHLDMTIREHRGEMEQKI-IKLEGTLEKSELELKECNKQI 746
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
+ + +LQ +Q + + E+ +++ E+ + + +E +E + +
Sbjct: 747 ESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQC 806
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
++L Q+L + EL A+ R+Q+VQ + + +E L E E +
Sbjct: 807 KEAIDLG-------QKLRLTREQVQNSHTEL--AEARHQQVQAQRE--IERLSSELEDMK 855
Query: 490 KIEAVKKS----LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
++ K + L E+ VR +EA K++ +++E+ + +E+ + H
Sbjct: 856 QLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENH 915
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
A+ ++ ++++ Q E+ + + QD++ Q+V
Sbjct: 916 AKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQV 957
Score = 48.8 bits (111), Expect = 6e-05
Identities = 87/449 (19%), Positives = 191/449 (42%), Gaps = 40/449 (8%)
Query: 244 TETVRVRETSPTTCVVRINTELPAIDN------SYLNQLNELKETVKQFDDLSVYILNDS 297
T V + T ++++ +EL D S +N+ ELK V ++ + +
Sbjct: 5 TSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNE-RLDLCQQE 63
Query: 298 SKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL-QIQITELELSLD----VANKTNIDLQ 352
+ + +E+ L + ++ LK E+ K L + Q++ D + +
Sbjct: 64 IESSRVELRSLEKII--SQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVIS 121
Query: 353 KTIKKQSLQLTEIQT-HYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR-GNYEQALRV 410
+ K +++ EIQ H + QL +L +Q + + E E ++ G ++ A V
Sbjct: 122 ELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESV 181
Query: 411 K----RSVEQQYEESQTR----VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRI 462
K ++ +QYE+ + R + EL + + + + ++ +A + + I +EL
Sbjct: 182 KDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLE 241
Query: 463 ADERYQRVQTELKHTVEHL----HEEQERIV---KIEAVKKSLEIEVKNISVRLEEVEAN 515
++++E+ L + +E+IV I A LE E+ + ++ +E N
Sbjct: 242 KASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETN 301
Query: 516 AIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL 575
++I E + K + LE +H E K + + E QL++ Q +E +K +S+
Sbjct: 302 INTEHEKICLAFE-KAKKIHLE------QHKEMEKQIERLEAQLEKKDQQFKEQEKTMSM 354
Query: 576 LQDSLEKTSQKVSIYKRQLAEQEG-MSQQSVTRVRRFQR-ELEAAEDRADVAESNLSLIR 633
LQ + + R L E +G M ++++ + + + + +E+ V + + +L
Sbjct: 355 LQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEI 414
Query: 634 AKHRTFVTTSTVPGSQVYLVQESRALSSE 662
K + + + G++ ++ + S E
Sbjct: 415 CKEELVLHLNQLEGNKEKFEKQLKKKSEE 443
>AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 73.7 bits (173), Expect = 2e-12
Identities = 83/334 (24%), Positives = 156/334 (46%), Gaps = 33/334 (9%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
E + LN R +E E K + + R K +L+ Q L+ ++D NK +L+K + L
Sbjct: 815 EQQTLN-RALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNK---ELEKIGEDSKQALQ 870
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
++Q ++ + + + + AQR+ + E E+ G + + + Q + SQ
Sbjct: 871 QLQAQLEDYKEKAR---REVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQA 927
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL---KHTVEH 480
+ + L+ +EQE D+ ++L+ +E+ R++TEL K+TVE
Sbjct: 928 ERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVEL 987
Query: 481 LHEE----------------QERIVK--IEAVKKSLEIEVKNISVRLEEVEANAIVGGKR 522
L + QER + +E K SLE + K++ RL E
Sbjct: 988 LTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSAS- 1046
Query: 523 IISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
+S+LE++ + ++ L E+R RK ER++KE+ IQ E+++++++ D ++
Sbjct: 1047 -LSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVN---DQKDQ 1102
Query: 583 TSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
S +V KRQ+ E E ++ ++ QRE+E
Sbjct: 1103 LSLRVKALKRQVDEAEEEIERLDGLRKKAQREVE 1136
Score = 54.4 bits (125), Expect = 1e-06
Identities = 74/368 (20%), Positives = 164/368 (44%), Gaps = 28/368 (7%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
E+ L + E EV ++++ Q +L S+ A + + L+ +K S +
Sbjct: 496 ELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVR 555
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+Q R+L+ T ++ G Q Q E++R ++ L+++ E+ EE
Sbjct: 556 GLQ-------RELEETSEETGHWQSMFQK---NKEDLRATKQELLQLRMEKEEMEEELGE 605
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
++ E+ + + + A +++ ++ + +EL+ Q + +H L E
Sbjct: 606 KI-EVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDREL-E 663
Query: 484 EQERIVKIEAVKKSLEIEVKNISVR--LEEVEANAIVGGK-RIISKLEARIKD-----ME 535
+Q ++++EA + E+E +N+ ++ L+++ + K +++++ EA + +E
Sbjct: 664 KQLAVLRVEA-DRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVE 722
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
L E + + E + + E+QLKE + + + L+D L Q++ K+QL
Sbjct: 723 TTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKL----QRLEAEKQQLE 778
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
E SQ+ + +R LEA R + A+ L+ + + +T G Q +++
Sbjct: 779 EALNASQEEEGSLAAAKRALEA---RLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRR 835
Query: 656 SRALSSER 663
+A E+
Sbjct: 836 GKAELEEQ 843
Score = 50.0 bits (114), Expect = 3e-05
Identities = 94/466 (20%), Positives = 196/466 (42%), Gaps = 33/466 (7%)
Query: 143 KKRMQEIEKELDLYEKEVNLGS--ELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
++R+ +E++L V+ G E R + + R ++ K + L S+ + K
Sbjct: 736 RRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAK 795
Query: 201 PDFQASRTLVNRDYTNLSKN--VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCV 258
+A R L + L +AL E R + E R+ + + V
Sbjct: 796 RALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRT----V 851
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
R+N EL I L +L+ ++ + + + + D+ +Q + + ++
Sbjct: 852 DRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAE-KTSGGLSR 910
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L+ E+ R+++ LQ E D A L K + Q LQ E + + +R
Sbjct: 911 LQDEIQRLRQALQASQAER----DTAR-----LDKELLAQRLQGLEQEA--ENKKRSQDD 959
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQAL-RVKRSVEQQYEESQTRVNELTVINVNLSS 437
Q + ++ L E++E + E RV R Q ++ +T + + +L
Sbjct: 960 RARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRG-RDQVDQLRTELMQERSARQDLEC 1018
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
K +E++ + ++ + +++++ + E L E+ +++ +
Sbjct: 1019 DKISLERQNKDLKTRLAS-SEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK 1077
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK-E 556
LE +VK +S+++E+ + V ++ +L R+K ++ ++DE + E + LRKK +
Sbjct: 1078 LERKVKELSIQIEDERQH--VNDQK--DQLSLRVKALKRQVDEAE-EEIERLDGLRKKAQ 1132
Query: 557 RQLKEVIIQCEEDQKNI-SLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
R+++E E+ Q I SL +DS K S+ + + EG+S
Sbjct: 1133 REVEEQHEVNEQLQARIKSLEKDSWRKASRSAA---ESALKNEGLS 1175
Score = 49.6 bits (113), Expect = 3e-05
Identities = 101/493 (20%), Positives = 205/493 (41%), Gaps = 30/493 (6%)
Query: 165 ELRQKAAMYRG-KSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLS---KN 220
EL+ K +G + AK + L E+R ++ K + L R+ T L K
Sbjct: 447 ELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKE 506
Query: 221 VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELK 280
+A E + + R TE + +++ T + ++ A+ +L E
Sbjct: 507 EVASRDQEVEHVRQQYQRDTEQLRRSMQ-DATQDHAVLEAERQKMSALVRGLQRELEETS 565
Query: 281 ETVKQFDDLSVYILN-DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL-QIQITELE 338
E + S++ N + + T E+ QL E E +L ++ ++++L Q + + +
Sbjct: 566 EETGHWQ--SMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGD 623
Query: 339 L-SLDVANKTNIDLQKTIKKQSL--QLTEIQ-THYD-EVQRQL---QVTLDQYGVAQRRI 390
++V K + Q+ +K+ Q E+ H D E+++QL +V D+ + +
Sbjct: 624 TRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQN 683
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVE-------QQYEESQTRVNELTVINVNLSSSKAKIE 443
L ++++R + E+A + K E Q+ +T + E N +E
Sbjct: 684 LQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLE 743
Query: 444 QELAIVAADYDE-ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
Q+L D E R+ D + QR++ E + E L+ QE + A K++LE +
Sbjct: 744 QQLKETRGLVDGGEAVEARLRD-KLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARL 802
Query: 503 KNISVRLEEV--EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+ L + E + K ++ + EL+E+KR T+ L K+ ++
Sbjct: 803 EEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIG 862
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
E Q + + + L+D EK ++V+ +RQ + ++++ + R Q E++
Sbjct: 863 EDSKQALQQLQ--AQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQ 920
Query: 621 RADVAESNLSLIR 633
+++ R
Sbjct: 921 ALQASQAERDTAR 933
Score = 47.6 bits (108), Expect = 1e-04
Identities = 77/354 (21%), Positives = 152/354 (42%), Gaps = 33/354 (9%)
Query: 281 ETVKQFDDLSVYILNDSSKQTSIEIEQLNA-RVVEAETKLKSEVTRIKKKLQIQITELEL 339
E ++ ++L + + K+ +E Q+ R +E +T+ E +R+++ L+ + E
Sbjct: 363 ELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTE---ECSRLQELLERRKGE--- 416
Query: 340 SLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ-RQLQVTLDQYGVAQRRIQSLTGEVE 398
A ++N +LQ K+ L E H E Q +LQ L + + L ++
Sbjct: 417 ----AQQSNKELQNM--KRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLL 470
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
E R E+ L K+ VE+Q + R ELT + L A +QE+ V Y T+
Sbjct: 471 ETRELLEEVLEGKQRVEEQL---RLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTE 527
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+LR ++ T +H E ER K+ A+ + L+ E++ S + +
Sbjct: 528 QLR---------RSMQDATQDHAVLEAER-QKMSALVRGLQRELEETSEETGHWQ-SMFQ 576
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K + + + + +E +E + E I++L+++ Q + D + + +L+
Sbjct: 577 KNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQAR----ASAGDTRQVEVLKK 632
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA-DVAESNLSL 631
L +T +++ + + QE + + + L DR ++ E NL L
Sbjct: 633 ELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQL 686
Score = 43.2 bits (97), Expect = 0.003
Identities = 70/342 (20%), Positives = 144/342 (42%), Gaps = 39/342 (11%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L + + Q ++QL EA +K K L + +E +L + N + ++
Sbjct: 679 LEEQNLQLQKTLQQLRQDCEEA-SKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRR 737
Query: 354 TIKKQSLQLTEIQTHYD---EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV 410
I QL E + D V+ +L+ L + +++++ +E G+ A
Sbjct: 738 RILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAA--- 794
Query: 411 KRSVEQQYEESQTRV----NELTVINVNLSS----------SKAKIEQELAIVAADYDEI 456
KR++E + EE+Q + E +N L KA++E++ ++ D +
Sbjct: 795 KRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRL 854
Query: 457 TKELRIADERYQRVQTELKHTVEHLHEEQERIV----------KIEAVKKS-----LEIE 501
KEL E ++ +L+ +E E+ R V EA K S L+ E
Sbjct: 855 NKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDE 914
Query: 502 VKNISVRLEEVEANAIVGGKRIISKLEA-RIKDMELELDEEKRRHAETIKILRKKERQLK 560
++ + L+ +A R+ +L A R++ +E E + +KR + + L+ E ++
Sbjct: 915 IQRLRQALQASQAERDTA--RLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVS 972
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ + +E++ + LL D + + +V + +L ++ Q
Sbjct: 973 RLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQ 1014
Score = 37.1 bits (82), Expect = 0.20
Identities = 25/119 (21%), Positives = 63/119 (52%), Gaps = 5/119 (4%)
Query: 503 KNISVRLEEVEANAIV--GGKRIIS---KLEARIKDMELELDEEKRRHAETIKILRKKER 557
+ +S+ LE+++ +V G + ++ +L ++++++ +LDEE ++ + ER
Sbjct: 335 RKVSLVLEKMQPLVMVSSGSTKAVAGQGELTRKVEELQRKLDEEVKKRQKLEPSQVGLER 394
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
QL+E +C Q+ + + +++++++ KR L + E + T+V Q +L+
Sbjct: 395 QLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLK 453
>AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 73.7 bits (173), Expect = 2e-12
Identities = 83/334 (24%), Positives = 156/334 (46%), Gaps = 33/334 (9%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
E + LN R +E E K + + R K +L+ Q L+ ++D NK +L+K + L
Sbjct: 815 EQQTLN-RALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNK---ELEKIGEDSKQALQ 870
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
++Q ++ + + + + AQR+ + E E+ G + + + Q + SQ
Sbjct: 871 QLQAQLEDYKEKAR---REVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQA 927
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL---KHTVEH 480
+ + L+ +EQE D+ ++L+ +E+ R++TEL K+TVE
Sbjct: 928 ERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVEL 987
Query: 481 LHEE----------------QERIVK--IEAVKKSLEIEVKNISVRLEEVEANAIVGGKR 522
L + QER + +E K SLE + K++ RL E
Sbjct: 988 LTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSAS- 1046
Query: 523 IISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
+S+LE++ + ++ L E+R RK ER++KE+ IQ E+++++++ D ++
Sbjct: 1047 -LSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVN---DQKDQ 1102
Query: 583 TSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
S +V KRQ+ E E ++ ++ QRE+E
Sbjct: 1103 LSLRVKALKRQVDEAEEEIERLDGLRKKAQREVE 1136
Score = 54.4 bits (125), Expect = 1e-06
Identities = 74/368 (20%), Positives = 164/368 (44%), Gaps = 28/368 (7%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
E+ L + E EV ++++ Q +L S+ A + + L+ +K S +
Sbjct: 496 ELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVR 555
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+Q R+L+ T ++ G Q Q E++R ++ L+++ E+ EE
Sbjct: 556 GLQ-------RELEETSEETGHWQSMFQK---NKEDLRATKQELLQLRMEKEEMEEELGE 605
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
++ E+ + + + A +++ ++ + +EL+ Q + +H L E
Sbjct: 606 KI-EVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDREL-E 663
Query: 484 EQERIVKIEAVKKSLEIEVKNISVR--LEEVEANAIVGGK-RIISKLEARIKD-----ME 535
+Q ++++EA + E+E +N+ ++ L+++ + K +++++ EA + +E
Sbjct: 664 KQLAVLRVEA-DRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVE 722
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
L E + + E + + E+QLKE + + + L+D L Q++ K+QL
Sbjct: 723 TTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKL----QRLEAEKQQLE 778
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
E SQ+ + +R LEA R + A+ L+ + + +T G Q +++
Sbjct: 779 EALNASQEEEGSLAAAKRALEA---RLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRR 835
Query: 656 SRALSSER 663
+A E+
Sbjct: 836 GKAELEEQ 843
Score = 50.0 bits (114), Expect = 3e-05
Identities = 94/466 (20%), Positives = 196/466 (42%), Gaps = 33/466 (7%)
Query: 143 KKRMQEIEKELDLYEKEVNLGS--ELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
++R+ +E++L V+ G E R + + R ++ K + L S+ + K
Sbjct: 736 RRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAK 795
Query: 201 PDFQASRTLVNRDYTNLSKN--VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCV 258
+A R L + L +AL E R + E R+ + + V
Sbjct: 796 RALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRT----V 851
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
R+N EL I L +L+ ++ + + + + D+ +Q + + ++
Sbjct: 852 DRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAE-KTSGGLSR 910
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L+ E+ R+++ LQ E D A L K + Q LQ E + + +R
Sbjct: 911 LQDEIQRLRQALQASQAER----DTAR-----LDKELLAQRLQGLEQEA--ENKKRSQDD 959
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQAL-RVKRSVEQQYEESQTRVNELTVINVNLSS 437
Q + ++ L E++E + E RV R Q ++ +T + + +L
Sbjct: 960 RARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRG-RDQVDQLRTELMQERSARQDLEC 1018
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
K +E++ + ++ + +++++ + E L E+ +++ +
Sbjct: 1019 DKISLERQNKDLKTRLAS-SEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK 1077
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK-E 556
LE +VK +S+++E+ + V ++ +L R+K ++ ++DE + E + LRKK +
Sbjct: 1078 LERKVKELSIQIEDERQH--VNDQK--DQLSLRVKALKRQVDEAE-EEIERLDGLRKKAQ 1132
Query: 557 RQLKEVIIQCEEDQKNI-SLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
R+++E E+ Q I SL +DS K S+ + + EG+S
Sbjct: 1133 REVEEQHEVNEQLQARIKSLEKDSWRKASRSAA---ESALKNEGLS 1175
Score = 49.6 bits (113), Expect = 3e-05
Identities = 101/493 (20%), Positives = 205/493 (41%), Gaps = 30/493 (6%)
Query: 165 ELRQKAAMYRG-KSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLS---KN 220
EL+ K +G + AK + L E+R ++ K + L R+ T L K
Sbjct: 447 ELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKE 506
Query: 221 VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELK 280
+A E + + R TE + +++ T + ++ A+ +L E
Sbjct: 507 EVASRDQEVEHVRQQYQRDTEQLRRSMQ-DATQDHAVLEAERQKMSALVRGLQRELEETS 565
Query: 281 ETVKQFDDLSVYILN-DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL-QIQITELE 338
E + S++ N + + T E+ QL E E +L ++ ++++L Q + + +
Sbjct: 566 EETGHWQ--SMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGD 623
Query: 339 L-SLDVANKTNIDLQKTIKKQSL--QLTEIQ-THYD-EVQRQL---QVTLDQYGVAQRRI 390
++V K + Q+ +K+ Q E+ H D E+++QL +V D+ + +
Sbjct: 624 TRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQN 683
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVE-------QQYEESQTRVNELTVINVNLSSSKAKIE 443
L ++++R + E+A + K E Q+ +T + E N +E
Sbjct: 684 LQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLE 743
Query: 444 QELAIVAADYDE-ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
Q+L D E R+ D + QR++ E + E L+ QE + A K++LE +
Sbjct: 744 QQLKETRGLVDGGEAVEARLRD-KLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARL 802
Query: 503 KNISVRLEEV--EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+ L + E + K ++ + EL+E+KR T+ L K+ ++
Sbjct: 803 EEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIG 862
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
E Q + + + L+D EK ++V+ +RQ + ++++ + R Q E++
Sbjct: 863 EDSKQALQQLQ--AQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQ 920
Query: 621 RADVAESNLSLIR 633
+++ R
Sbjct: 921 ALQASQAERDTAR 933
Score = 47.6 bits (108), Expect = 1e-04
Identities = 77/354 (21%), Positives = 152/354 (42%), Gaps = 33/354 (9%)
Query: 281 ETVKQFDDLSVYILNDSSKQTSIEIEQLNA-RVVEAETKLKSEVTRIKKKLQIQITELEL 339
E ++ ++L + + K+ +E Q+ R +E +T+ E +R+++ L+ + E
Sbjct: 363 ELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTE---ECSRLQELLERRKGE--- 416
Query: 340 SLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ-RQLQVTLDQYGVAQRRIQSLTGEVE 398
A ++N +LQ K+ L E H E Q +LQ L + + L ++
Sbjct: 417 ----AQQSNKELQNM--KRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLL 470
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
E R E+ L K+ VE+Q + R ELT + L A +QE+ V Y T+
Sbjct: 471 ETRELLEEVLEGKQRVEEQL---RLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTE 527
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+LR ++ T +H E ER K+ A+ + L+ E++ S + +
Sbjct: 528 QLR---------RSMQDATQDHAVLEAER-QKMSALVRGLQRELEETSEETGHWQ-SMFQ 576
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K + + + + +E +E + E I++L+++ Q + D + + +L+
Sbjct: 577 KNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQAR----ASAGDTRQVEVLKK 632
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA-DVAESNLSL 631
L +T +++ + + QE + + + L DR ++ E NL L
Sbjct: 633 ELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQL 686
Score = 43.2 bits (97), Expect = 0.003
Identities = 70/342 (20%), Positives = 144/342 (42%), Gaps = 39/342 (11%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L + + Q ++QL EA +K K L + +E +L + N + ++
Sbjct: 679 LEEQNLQLQKTLQQLRQDCEEA-SKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRR 737
Query: 354 TIKKQSLQLTEIQTHYD---EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV 410
I QL E + D V+ +L+ L + +++++ +E G+ A
Sbjct: 738 RILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAA--- 794
Query: 411 KRSVEQQYEESQTRV----NELTVINVNLSS----------SKAKIEQELAIVAADYDEI 456
KR++E + EE+Q + E +N L KA++E++ ++ D +
Sbjct: 795 KRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRL 854
Query: 457 TKELRIADERYQRVQTELKHTVEHLHEEQERIV----------KIEAVKKS-----LEIE 501
KEL E ++ +L+ +E E+ R V EA K S L+ E
Sbjct: 855 NKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDE 914
Query: 502 VKNISVRLEEVEANAIVGGKRIISKLEA-RIKDMELELDEEKRRHAETIKILRKKERQLK 560
++ + L+ +A R+ +L A R++ +E E + +KR + + L+ E ++
Sbjct: 915 IQRLRQALQASQAERDTA--RLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVS 972
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ + +E++ + LL D + + +V + +L ++ Q
Sbjct: 973 RLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQ 1014
Score = 37.1 bits (82), Expect = 0.20
Identities = 25/119 (21%), Positives = 63/119 (52%), Gaps = 5/119 (4%)
Query: 503 KNISVRLEEVEANAIV--GGKRIIS---KLEARIKDMELELDEEKRRHAETIKILRKKER 557
+ +S+ LE+++ +V G + ++ +L ++++++ +LDEE ++ + ER
Sbjct: 335 RKVSLVLEKMQPLVMVSSGSTKAVAGQGELTRKVEELQRKLDEEVKKRQKLEPSQVGLER 394
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
QL+E +C Q+ + + +++++++ KR L + E + T+V Q +L+
Sbjct: 395 QLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLK 453
>AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein.
Length = 1208
Score = 73.7 bits (173), Expect = 2e-12
Identities = 83/334 (24%), Positives = 156/334 (46%), Gaps = 33/334 (9%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
E + LN R +E E K + + R K +L+ Q L+ ++D NK +L+K + L
Sbjct: 820 EQQTLN-RALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNK---ELEKIGEDSKQALQ 875
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
++Q ++ + + + + AQR+ + E E+ G + + + Q + SQ
Sbjct: 876 QLQAQLEDYKEKAR---REVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQA 932
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL---KHTVEH 480
+ + L+ +EQE D+ ++L+ +E+ R++TEL K+TVE
Sbjct: 933 ERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVEL 992
Query: 481 LHEE----------------QERIVK--IEAVKKSLEIEVKNISVRLEEVEANAIVGGKR 522
L + QER + +E K SLE + K++ RL E
Sbjct: 993 LTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSAS- 1051
Query: 523 IISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
+S+LE++ + ++ L E+R RK ER++KE+ IQ E+++++++ D ++
Sbjct: 1052 -LSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVN---DQKDQ 1107
Query: 583 TSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
S +V KRQ+ E E ++ ++ QRE+E
Sbjct: 1108 LSLRVKALKRQVDEAEEEIERLDGLRKKAQREVE 1141
Score = 54.4 bits (125), Expect = 1e-06
Identities = 74/368 (20%), Positives = 164/368 (44%), Gaps = 28/368 (7%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
E+ L + E EV ++++ Q +L S+ A + + L+ +K S +
Sbjct: 501 ELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVR 560
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+Q R+L+ T ++ G Q Q E++R ++ L+++ E+ EE
Sbjct: 561 GLQ-------RELEETSEETGHWQSMFQK---NKEDLRATKQELLQLRMEKEEMEEELGE 610
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
++ E+ + + + A +++ ++ + +EL+ Q + +H L E
Sbjct: 611 KI-EVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDREL-E 668
Query: 484 EQERIVKIEAVKKSLEIEVKNISVR--LEEVEANAIVGGK-RIISKLEARIKD-----ME 535
+Q ++++EA + E+E +N+ ++ L+++ + K +++++ EA + +E
Sbjct: 669 KQLAVLRVEA-DRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVE 727
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
L E + + E + + E+QLKE + + + L+D L Q++ K+QL
Sbjct: 728 TTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKL----QRLEAEKQQLE 783
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
E SQ+ + +R LEA R + A+ L+ + + +T G Q +++
Sbjct: 784 EALNASQEEEGSLAAAKRALEA---RLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRR 840
Query: 656 SRALSSER 663
+A E+
Sbjct: 841 GKAELEEQ 848
Score = 50.0 bits (114), Expect = 3e-05
Identities = 94/466 (20%), Positives = 196/466 (42%), Gaps = 33/466 (7%)
Query: 143 KKRMQEIEKELDLYEKEVNLGS--ELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
++R+ +E++L V+ G E R + + R ++ K + L S+ + K
Sbjct: 741 RRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAK 800
Query: 201 PDFQASRTLVNRDYTNLSKN--VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCV 258
+A R L + L +AL E R + E R+ + + V
Sbjct: 801 RALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRT----V 856
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
R+N EL I L +L+ ++ + + + + D+ +Q + + ++
Sbjct: 857 DRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAE-KTSGGLSR 915
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L+ E+ R+++ LQ E D A L K + Q LQ E + + +R
Sbjct: 916 LQDEIQRLRQALQASQAER----DTAR-----LDKELLAQRLQGLEQEA--ENKKRSQDD 964
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQAL-RVKRSVEQQYEESQTRVNELTVINVNLSS 437
Q + ++ L E++E + E RV R Q ++ +T + + +L
Sbjct: 965 RARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRG-RDQVDQLRTELMQERSARQDLEC 1023
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
K +E++ + ++ + +++++ + E L E+ +++ +
Sbjct: 1024 DKISLERQNKDLKTRLAS-SEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK 1082
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK-E 556
LE +VK +S+++E+ + V ++ +L R+K ++ ++DE + E + LRKK +
Sbjct: 1083 LERKVKELSIQIEDERQH--VNDQK--DQLSLRVKALKRQVDEAE-EEIERLDGLRKKAQ 1137
Query: 557 RQLKEVIIQCEEDQKNI-SLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
R+++E E+ Q I SL +DS K S+ + + EG+S
Sbjct: 1138 REVEEQHEVNEQLQARIKSLEKDSWRKASRSAA---ESALKNEGLS 1180
Score = 49.6 bits (113), Expect = 3e-05
Identities = 101/493 (20%), Positives = 205/493 (41%), Gaps = 30/493 (6%)
Query: 165 ELRQKAAMYRG-KSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLS---KN 220
EL+ K +G + AK + L E+R ++ K + L R+ T L K
Sbjct: 452 ELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKE 511
Query: 221 VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELK 280
+A E + + R TE + +++ T + ++ A+ +L E
Sbjct: 512 EVASRDQEVEHVRQQYQRDTEQLRRSMQ-DATQDHAVLEAERQKMSALVRGLQRELEETS 570
Query: 281 ETVKQFDDLSVYILN-DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL-QIQITELE 338
E + S++ N + + T E+ QL E E +L ++ ++++L Q + + +
Sbjct: 571 EETGHWQ--SMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGD 628
Query: 339 L-SLDVANKTNIDLQKTIKKQSL--QLTEIQ-THYD-EVQRQL---QVTLDQYGVAQRRI 390
++V K + Q+ +K+ Q E+ H D E+++QL +V D+ + +
Sbjct: 629 TRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQN 688
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVE-------QQYEESQTRVNELTVINVNLSSSKAKIE 443
L ++++R + E+A + K E Q+ +T + E N +E
Sbjct: 689 LQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLE 748
Query: 444 QELAIVAADYDE-ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
Q+L D E R+ D + QR++ E + E L+ QE + A K++LE +
Sbjct: 749 QQLKETRGLVDGGEAVEARLRD-KLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARL 807
Query: 503 KNISVRLEEV--EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+ L + E + K ++ + EL+E+KR T+ L K+ ++
Sbjct: 808 EEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIG 867
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
E Q + + + L+D EK ++V+ +RQ + ++++ + R Q E++
Sbjct: 868 EDSKQALQQLQ--AQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQ 925
Query: 621 RADVAESNLSLIR 633
+++ R
Sbjct: 926 ALQASQAERDTAR 938
Score = 47.6 bits (108), Expect = 1e-04
Identities = 77/354 (21%), Positives = 152/354 (42%), Gaps = 33/354 (9%)
Query: 281 ETVKQFDDLSVYILNDSSKQTSIEIEQLNA-RVVEAETKLKSEVTRIKKKLQIQITELEL 339
E ++ ++L + + K+ +E Q+ R +E +T+ E +R+++ L+ + E
Sbjct: 368 ELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTE---ECSRLQELLERRKGE--- 421
Query: 340 SLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ-RQLQVTLDQYGVAQRRIQSLTGEVE 398
A ++N +LQ K+ L E H E Q +LQ L + + L ++
Sbjct: 422 ----AQQSNKELQNM--KRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLL 475
Query: 399 EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
E R E+ L K+ VE+Q + R ELT + L A +QE+ V Y T+
Sbjct: 476 ETRELLEEVLEGKQRVEEQL---RLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTE 532
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
+LR ++ T +H E ER K+ A+ + L+ E++ S + +
Sbjct: 533 QLR---------RSMQDATQDHAVLEAER-QKMSALVRGLQRELEETSEETGHWQ-SMFQ 581
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
K + + + + +E +E + E I++L+++ Q + D + + +L+
Sbjct: 582 KNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQAR----ASAGDTRQVEVLKK 637
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA-DVAESNLSL 631
L +T +++ + + QE + + + L DR ++ E NL L
Sbjct: 638 ELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQL 691
Score = 43.2 bits (97), Expect = 0.003
Identities = 70/342 (20%), Positives = 144/342 (42%), Gaps = 39/342 (11%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L + + Q ++QL EA +K K L + +E +L + N + ++
Sbjct: 684 LEEQNLQLQKTLQQLRQDCEEA-SKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRR 742
Query: 354 TIKKQSLQLTEIQTHYD---EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV 410
I QL E + D V+ +L+ L + +++++ +E G+ A
Sbjct: 743 RILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAA--- 799
Query: 411 KRSVEQQYEESQTRV----NELTVINVNLSS----------SKAKIEQELAIVAADYDEI 456
KR++E + EE+Q + E +N L KA++E++ ++ D +
Sbjct: 800 KRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRL 859
Query: 457 TKELRIADERYQRVQTELKHTVEHLHEEQERIV----------KIEAVKKS-----LEIE 501
KEL E ++ +L+ +E E+ R V EA K S L+ E
Sbjct: 860 NKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDE 919
Query: 502 VKNISVRLEEVEANAIVGGKRIISKLEA-RIKDMELELDEEKRRHAETIKILRKKERQLK 560
++ + L+ +A R+ +L A R++ +E E + +KR + + L+ E ++
Sbjct: 920 IQRLRQALQASQAERDTA--RLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVS 977
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ + +E++ + LL D + + +V + +L ++ Q
Sbjct: 978 RLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQ 1019
Score = 37.1 bits (82), Expect = 0.20
Identities = 25/119 (21%), Positives = 63/119 (52%), Gaps = 5/119 (4%)
Query: 503 KNISVRLEEVEANAIV--GGKRIIS---KLEARIKDMELELDEEKRRHAETIKILRKKER 557
+ +S+ LE+++ +V G + ++ +L ++++++ +LDEE ++ + ER
Sbjct: 340 RKVSLVLEKMQPLVMVSSGSTKAVAGQGELTRKVEELQRKLDEEVKKRQKLEPSQVGLER 399
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
QL+E +C Q+ + + +++++++ KR L + E + T+V Q +L+
Sbjct: 400 QLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLK 458
>AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein.
Length = 864
Score = 73.7 bits (173), Expect = 2e-12
Identities = 105/544 (19%), Positives = 241/544 (44%), Gaps = 59/544 (10%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+++ ++ +KEL +KE+ +L + + + + L ++ + + +E + K
Sbjct: 57 KEELLETADKELGEAKKEIK--RKLSEMQDLEETMAKLQLELNLCQKEKERLSDELLVKS 114
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
D + + ++ LSK V + A+ E + + E ++ R+ SP+ R+
Sbjct: 115 DLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVERMRLE---HGIKRRDRSPS----RL 167
Query: 262 NTELPAIDNS---YLNQLNELKETVKQFDDLSVYILND-SSKQTSIEIEQLNARVVEAET 317
+T L I+ Y +L L+ +++ + Y + SS + E N+ +
Sbjct: 168 DTFLKGIEEERDYYKKELERLQHIIQRRSCSTSYSAREKSSIFRTPEKGDYNSEI----- 222
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
++TR + +LQ + E ++ D+Q +K + + ++ Y+E Q +L
Sbjct: 223 ---HQITRERDELQRMLERFEKYME-------DIQSNVKLLTAERDKLSVLYNEAQEELS 272
Query: 378 VTLDQ--YGVAQRRIQSLTGEVEEIR-GNYEQALRVKRSVEQQYE-----------ESQT 423
+ A I SL + +E+ + + + K ++ ++ E E +
Sbjct: 273 ALRKESTQTTAPHNIVSLMEKEKELALSDLRRIMAEKEALREKLEHIEEVSLFGKSELEK 332
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
+ LT +N L S K +++ ++ I+ + + +L++ +++ V + H +
Sbjct: 333 TIEHLTCVNHQLESEKYELKSKVLIMKETIESLENKLKVQAQKFSHVAGDSSH--QKTEV 390
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELEL---DE 540
RIV E +++S++ +S++ E+E+ + I LE +I ++ L++ DE
Sbjct: 391 NSLRIVN-EQLQRSVDDYQHRLSIKRGELES-----AQAQIKILEEKIDELNLKMTSQDE 444
Query: 541 EKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE-QEG 599
E +TI ++ K++ L+E + +E + I+ LQ++L + V+ K ++E +
Sbjct: 445 EAHVMKKTIGVIDKEKDFLQETV---DEKTEKIANLQENLANKEKAVAQMKIMISECESS 501
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLI-RAKHRTFVTTSTVPGSQVYLVQESRA 658
++Q T V R RE+ + + D A L + R++ F + + +E++
Sbjct: 502 VNQLKETLVNR-DREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQE 560
Query: 659 LSSE 662
+S E
Sbjct: 561 ISLE 564
Score = 45.2 bits (102), Expect = 7e-04
Identities = 64/341 (18%), Positives = 140/341 (41%), Gaps = 25/341 (7%)
Query: 305 IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
+++ ++ + L ++ + + ++I I+E E S++ +T ++ + I QL
Sbjct: 467 VDEKTEKIANLQENLANKEKAVAQ-MKIMISECESSVNQLKETLVNRDREINSLRRQLDA 525
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
DEV R ++ + Q + ++ E +EI E A++ K ++ + + T
Sbjct: 526 AHKELDEVGRSREIAFKENRRLQDDLATMARENQEISLELEAAVQEKEEMKSRVHKYITE 585
Query: 425 VNELTVINVNLSSSKAKIEQEL--------------AIVAADYDEITKELRIADERYQRV 470
V+ +L ++K K Q+L + A + + +R+
Sbjct: 586 VSRWE----SLMAAKEKENQDLLDRFQMLHNRAEDWEVKAHQAEGESSSVRLELLSIDTE 641
Query: 471 QTELKHTVEHLHEE-QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEA 529
+ L+ VE L +E QE I A + + K +S RLEE + +++ L +
Sbjct: 642 RRHLRERVELLEKEIQEHINAHHAYESQISSMAKAMS-RLEEELRHQEDEKATVLNDLSS 700
Query: 530 RIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
++++ ++LD K + L K + + V+++ E + LL+ L V
Sbjct: 701 -LRELCIKLDSGKDIMTQQ---LNSKNLEFERVVVELENVKSESDLLKKQLSNERHTVKN 756
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLS 630
+ LA S E++ +++ ++ES L+
Sbjct: 757 LESLLATNRDKEFHSHLTSHEKDTEIQLLKEKLTLSESKLT 797
Score = 44.4 bits (100), Expect = 0.001
Identities = 73/360 (20%), Positives = 147/360 (40%), Gaps = 27/360 (7%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
N+LK ++F ++ DSS Q + E+ L R+V + L+ V + +L I+ E
Sbjct: 367 NKLKVQAQKFS----HVAGDSSHQKT-EVNSL--RIVNEQ--LQRSVDDYQHRLSIKRGE 417
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
LE S K L++ I + +L++T +++ + V + Q + T +
Sbjct: 418 LE-SAQAQIKI---LEEKIDELNLKMTSQDEEAHVMKKTIGVIDKEKDFLQETVDEKTEK 473
Query: 397 VEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEI 456
+ ++ N + ++ E ++ VN+L VN + ++L + DE+
Sbjct: 474 IANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQLDAAHKELDEV 533
Query: 457 TKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANA 516
+ IA + +R+Q +L E QE +++EA + E + + EV
Sbjct: 534 GRSREIAFKENRRLQDDL---ATMARENQEISLELEAAVQEKEEMKSRVHKYITEV---- 586
Query: 517 IVGGKRIISKLEARIKDMELELDEEKRRH--AETIKI-LRKKERQLKEVIIQCEEDQKNI 573
R S + A+ K+ + LD + H AE ++ + E + V ++
Sbjct: 587 ----SRWESLMAAKEKENQDLLDRFQMLHNRAEDWEVKAHQAEGESSSVRLELLSIDTER 642
Query: 574 SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
L++ +E +++ + E + R + EL ED ++LS +R
Sbjct: 643 RHLRERVELLEKEIQEHINAHHAYESQISSMAKAMSRLEEELRHQEDEKATVLNDLSSLR 702
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 72.5 bits (170), Expect = 4e-12
Identities = 82/364 (22%), Positives = 160/364 (43%), Gaps = 30/364 (8%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARV----V 313
+ N + IDN + +QL +E + D L S+ + ++E ++ +
Sbjct: 705 KCNEQTKVIDN-FTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEI 763
Query: 314 E--AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
E AE+ S +TR + ++++T L+ +L ++ L+K ++ + E
Sbjct: 764 EKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVS 823
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGN---YEQALRVKRSVEQQY----EESQTR 424
VQR +Q T+++ + + L+ ++E++R N E R K E+Q E+ +
Sbjct: 824 VQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEND 883
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH-TVEHLHE 483
+ E+ ++ + SS K+ EL + D +E+ +L A+E +Q ++ TV+
Sbjct: 884 IAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQS 943
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
+QE K E KK LE ++ ++ ++E +L+AR E E K
Sbjct: 944 QQEAAKKHEEEKKELERKLSDLEKKMETSHNQC--------QELKAR---YERATSETKT 992
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+H E ++ L+K ++ + E+ N LLQ+ E Q Q AE +
Sbjct: 993 KHEEILQNLQKTLLDTEDKLKGAREE--NSGLLQELEELRKQAEKAKAAQTAEDAMQIME 1050
Query: 604 SVTR 607
+T+
Sbjct: 1051 QMTK 1054
Score = 64.9 bits (151), Expect = 9e-10
Identities = 100/524 (19%), Positives = 222/524 (42%), Gaps = 41/524 (7%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+K R+ E+EK+L L +EV +ELR++ + ++ +LL+E + + +
Sbjct: 462 EKSRIMELEKDLALRVQEV---AELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRT 518
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
D Q T + +++ + K + S+ ES+ + + +
Sbjct: 519 DHQREITSL-KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALW 577
Query: 262 NTELPAIDNSYLNQLNELKET--------VKQFDDLSVYI----LNDSSKQTSIEIEQLN 309
++L S+ + ELK + +F +L I L+ + +++ +Q +
Sbjct: 578 KSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDS 637
Query: 310 ARVVEAE--TKLKSEVTRIKKKLQIQITELELSLDVANKTN-IDLQKTIKK---QSLQLT 363
R A+ L++++ ++ K+ + + + LD A + ++++ T+ K +++
Sbjct: 638 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 697
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E++ + Q +V +D + + + +++ +R + + + QQ E ++
Sbjct: 698 ELEVLQAKCNEQTKV-IDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEK 756
Query: 424 RVNELTVINVNLSSSKA-KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ L I N SSKA I +EL + + L + + ++ EL+ E
Sbjct: 757 QIKHLE-IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFA 815
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E E V +V++S++ V + +E + N + + KL + DME + E+
Sbjct: 816 EASEEAV---SVQRSMQETVNKL--HQKEEQFNMLSSD---LEKLRENLADMEAKFREKD 867
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL---EKTSQKVSIYKRQLAEQEG 599
R + IK K E + E++ ++ ++ + D L E+ +++ + + E
Sbjct: 868 EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS 927
Query: 600 MSQQSV--TRVRRFQRELEAA---EDRADVAESNLSLIRAKHRT 638
Q+S+ V+ Q + EAA E+ E LS + K T
Sbjct: 928 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMET 971
Score = 63.3 bits (147), Expect = 3e-09
Identities = 79/390 (20%), Positives = 168/390 (43%), Gaps = 26/390 (6%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN--ARVVEAET 317
++ T + A D + LN+L+E ++ +DL + +S + +E+ ++ +R++E E
Sbjct: 412 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEK 471
Query: 318 KLK---SEVTRIKKKLQIQ--ITELELSLDVANKTNI---DLQKTIKKQSLQLTEIQTHY 369
L EV ++++L+ ++++SL + + + L+ T ++T ++ H+
Sbjct: 472 DLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHF 531
Query: 370 ----DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV-KRSVEQQYEESQTR 424
+ Q++++ + +SL ++E + + K +E Q
Sbjct: 532 GAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQA 591
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ EL V+ S E A + +++ + + E Q Q H E
Sbjct: 592 MEEL---KVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQD--SERAAHAKEM 646
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL-EARIKDMELELDEEKR 543
+ K+ V K E ++ I +L++ E +V + ++KL EA IK ELE+ + K
Sbjct: 647 EALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKC 706
Query: 544 RHAETIKILRKKERQLK---EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM 600
E K++ QLK E ++ + +K S + ++K Q++ ++Q+ E
Sbjct: 707 N--EQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIE 764
Query: 601 SQQSVTRVRRFQRELEAAEDRADVAESNLS 630
++ REL+ E + + NLS
Sbjct: 765 KNAESSKASSITRELQGRELKLTNLQENLS 794
Score = 42.7 bits (96), Expect = 0.004
Identities = 54/252 (21%), Positives = 117/252 (46%), Gaps = 33/252 (13%)
Query: 304 EIEQLNARVVEAETKLKSE-VTRIKKKLQIQITELELSLDVANKTNIDLQK---TIKKQS 359
E+E+L + +A+ +E +I +++ + TE SL+ +TN LQ T+K+ +
Sbjct: 1025 ELEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENN 1084
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE 419
L+ E +L + + V ++++ E+E ++ + A + + + E
Sbjct: 1085 LKNVE----------ELNKSKELLTVENQKMEEFRKEIETLK---QAAAQKSQQLSALQE 1131
Query: 420 ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE----LRIADERYQRVQTELK 475
E+ EL ++S + K+E+E +++ E+ K ++ ADE +Q +
Sbjct: 1132 ENVKLAEELGRSRDEVTSHQ-KLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSIS 1190
Query: 476 HTVEHLHEEQERIVKIE---AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
T L E+ + K+ V + K++ ++ +E++ + KLE ++K
Sbjct: 1191 ITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKV--------KLELKVK 1242
Query: 533 DMELELDEEKRR 544
++EL+L E KR+
Sbjct: 1243 NLELQLKENKRQ 1254
Score = 35.5 bits (78), Expect = 0.61
Identities = 58/269 (21%), Positives = 106/269 (39%), Gaps = 31/269 (11%)
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN-------VNLSSSKAKIEQ 444
S TG + E Y + + ++++ +E Q + +L +S +IEQ
Sbjct: 331 SRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQ 390
Query: 445 ELAI-----------VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
ELA+ + A D++ + AD + +L+ + + Q R+ +
Sbjct: 391 ELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESI 450
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVG-------GKRIISKLEARIKDMELELDEEKRRHA 546
K LE+ + R+ E+E + + +R+ S A DM L L +E
Sbjct: 451 TKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQ 510
Query: 547 ETIKILRKKERQ----LKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
E +++ R ++ LKE EE QK I L + EK S++ K +L E
Sbjct: 511 EKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKL-EHANKE 569
Query: 602 QQSVTRVRRFQRELEAAEDRADVAESNLS 630
V + + + E A + + E +S
Sbjct: 570 NSDVIALWKSKLETAIASHQQAMEELKVS 598
>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
protein.
Length = 1337
Score = 72.5 bits (170), Expect = 4e-12
Identities = 83/384 (21%), Positives = 166/384 (43%), Gaps = 40/384 (10%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
+L +L+E +D + + + K I + + E E K KS + ++K K + I
Sbjct: 972 KLKKLEEEQIILEDQNCKLAKEK-KLLEDRIAEFTTNLTEEEEKSKS-LAKLKNKHEAMI 1029
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
T+LE L K +L+KT +K T++ E+Q Q+ Q + +Q+
Sbjct: 1030 TDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAAL 1089
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
VEE AL+ R +E Q E ++++L A +
Sbjct: 1090 ARVEEEAAQKNMALKKIRELESQISE---------------------LQEDLESERASRN 1128
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRLE 510
+ K+ R E + ++TEL+ T++ +QE R ++ +KK+LE E K +++
Sbjct: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 511 EVEANAIVGGKRIISKLE------ARIKDMELELDEEKRRHAETIKILRK----KERQLK 560
E+ + + +LE A ++ + L+ E+ A +K+L + E + K
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK 1248
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
+V Q +E Q + + + + KV+ + +L G+ QS ++ + ++ A E
Sbjct: 1249 KVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES 1308
Query: 621 RADVAESNLSLIRAKHRTFVTTST 644
+ + L++ ++R ++ ST
Sbjct: 1309 Q---LQDTQELLQEENRQKLSLST 1329
Score = 67.3 bits (157), Expect = 2e-10
Identities = 66/324 (20%), Positives = 148/324 (45%), Gaps = 7/324 (2%)
Query: 306 EQLNARV---VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
EQL A EAE +L++ +T K++L+ +LE ++ + LQ KK +
Sbjct: 887 EQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNI 945
Query: 363 TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
E++ +E + Q + + +++ L E + + + K+ +E + E
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
T + E + +L+ K K E + + K+ + ++ ++++ + + +
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E Q +I +++ E E++ R+EE A + K+ I +LE++I +++ +L+ E+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK-IRELESQISELQEDLESER 1124
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ K R +L+ + + E+ + + Q+ K Q+V+I K+ L E+ +
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+ +R Q+ +A E+ A+ E
Sbjct: 1185 AQIQEMR--QKHSQAVEELAEQLE 1206
Score = 48.0 bits (109), Expect = 1e-04
Identities = 36/171 (21%), Positives = 83/171 (48%), Gaps = 1/171 (0%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++N LK+T+++ + + ++ S +E+L A +E ++K+ + + K+ L+ +
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEEL-AEQLEQTKRVKANLEKAKQTLENER 1226
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
EL + V + D + KK QL E+Q ++E +R D+ Q + ++T
Sbjct: 1227 GELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVT 1286
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQE 445
G + + + + ++E Q +++Q + E ++LS+ ++E E
Sbjct: 1287 GLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDE 1337
>BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for
IMAGE:5563109) protein.
Length = 1374
Score = 72.5 bits (170), Expect = 4e-12
Identities = 83/384 (21%), Positives = 166/384 (43%), Gaps = 40/384 (10%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
+L +L+E +D + + + K I + + E E K KS + ++K K + I
Sbjct: 972 KLKKLEEEQIILEDQNCKLAKEK-KLLEDRIAEFTTNLTEEEEKSKS-LAKLKNKHEAMI 1029
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
T+LE L K +L+KT +K T++ E+Q Q+ Q + +Q+
Sbjct: 1030 TDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAAL 1089
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
VEE AL+ R +E Q E ++++L A +
Sbjct: 1090 ARVEEEAAQKNMALKKIRELESQISE---------------------LQEDLESERASRN 1128
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQE----RIVKIEAVKKSLEIEVKNISVRLE 510
+ K+ R E + ++TEL+ T++ +QE R ++ +KK+LE E K +++
Sbjct: 1129 KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQ 1188
Query: 511 EVEANAIVGGKRIISKLE------ARIKDMELELDEEKRRHAETIKILRK----KERQLK 560
E+ + + +LE A ++ + L+ E+ A +K+L + E + K
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK 1248
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
+V Q +E Q + + + + KV+ + +L G+ QS ++ + ++ A E
Sbjct: 1249 KVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES 1308
Query: 621 RADVAESNLSLIRAKHRTFVTTST 644
+ + L++ ++R ++ ST
Sbjct: 1309 Q---LQDTQELLQEENRQKLSLST 1329
Score = 67.3 bits (157), Expect = 2e-10
Identities = 66/324 (20%), Positives = 148/324 (45%), Gaps = 7/324 (2%)
Query: 306 EQLNARV---VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
EQL A EAE +L++ +T K++L+ +LE ++ + LQ KK +
Sbjct: 887 EQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNI 945
Query: 363 TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
E++ +E + Q + + +++ L E + + + K+ +E + E
Sbjct: 946 QELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT 1005
Query: 423 TRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
T + E + +L+ K K E + + K+ + ++ ++++ + + +
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E Q +I +++ E E++ R+EE A + K+ I +LE++I +++ +L+ E+
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK-IRELESQISELQEDLESER 1124
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ K R +L+ + + E+ + + Q+ K Q+V+I K+ L E+ +
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 603 QSVTRVRRFQRELEAAEDRADVAE 626
+ +R Q+ +A E+ A+ E
Sbjct: 1185 AQIQEMR--QKHSQAVEELAEQLE 1206
Score = 48.0 bits (109), Expect = 1e-04
Identities = 36/171 (21%), Positives = 83/171 (48%), Gaps = 1/171 (0%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++N LK+T+++ + + ++ S +E+L A +E ++K+ + + K+ L+ +
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEEL-AEQLEQTKRVKANLEKAKQTLENER 1226
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
EL + V + D + KK QL E+Q ++E +R D+ Q + ++T
Sbjct: 1227 GELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVT 1286
Query: 395 GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQE 445
G + + + + ++E Q +++Q + E ++LS+ ++E E
Sbjct: 1287 GLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDE 1337
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 72.1 bits (169), Expect = 6e-12
Identities = 82/364 (22%), Positives = 160/364 (43%), Gaps = 30/364 (8%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARV----V 313
+ N + IDN + +QL +E + D L S+ + ++E ++ +
Sbjct: 740 KCNEQTKVIDN-FTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEI 798
Query: 314 E--AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
E AE+ S +TR + ++++T L+ +L ++ L+K ++ + E
Sbjct: 799 EKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVS 858
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGN---YEQALRVKRSVEQQY----EESQTR 424
VQR +Q T+++ + + L+ ++E++R N E R K E+Q E+ +
Sbjct: 859 VQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEND 918
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH-TVEHLHE 483
+ E+ ++ + SS K+ EL + D +E+ +L A+E +Q ++ TV+
Sbjct: 919 IAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQS 978
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
+QE K E KK LE ++ ++ ++E +L+AR E E K
Sbjct: 979 QQEAAKKHEEEKKELERKLSDLEKKMETSHNQC--------QELKAR---YERATSETKT 1027
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+H E ++ L+K ++ + E+ N LLQ+ E Q Q AE +
Sbjct: 1028 KHEEILQNLQKTLLDTEDKLKGAREE--NSGLLQELEELRKQADKAKAAQTAEDAMQIME 1085
Query: 604 SVTR 607
+T+
Sbjct: 1086 QMTK 1089
Score = 64.9 bits (151), Expect = 9e-10
Identities = 100/524 (19%), Positives = 222/524 (42%), Gaps = 41/524 (7%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+K R+ E+EK+L L +EV +ELR++ + ++ +LL+E + + +
Sbjct: 497 EKSRIMELEKDLALRVQEV---AELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRT 553
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
D Q T + +++ + K + S+ ES+ + + +
Sbjct: 554 DHQREITSL-KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALW 612
Query: 262 NTELPAIDNSYLNQLNELKET--------VKQFDDLSVYI----LNDSSKQTSIEIEQLN 309
++L S+ + ELK + +F +L I L+ + +++ +Q +
Sbjct: 613 KSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDS 672
Query: 310 ARVVEAE--TKLKSEVTRIKKKLQIQITELELSLDVANKTN-IDLQKTIKK---QSLQLT 363
R A+ L++++ ++ K+ + + + LD A + ++++ T+ K +++
Sbjct: 673 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 732
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E++ + Q +V +D + + + +++ +R + + + QQ E ++
Sbjct: 733 ELEVLQAKCNEQTKV-IDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEK 791
Query: 424 RVNELTVINVNLSSSKA-KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ L I N SSKA I +EL + + L + + ++ EL+ E
Sbjct: 792 QIKHLE-IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFA 850
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E E V +V++S++ V + +E + N + + KL + DME + E+
Sbjct: 851 EASEEAV---SVQRSMQETVNKL--HQKEEQFNMLSSD---LEKLRENLADMEAKFREKD 902
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL---EKTSQKVSIYKRQLAEQEG 599
R + IK K E + E++ ++ ++ + D L E+ +++ + + E
Sbjct: 903 EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS 962
Query: 600 MSQQSV--TRVRRFQRELEAA---EDRADVAESNLSLIRAKHRT 638
Q+S+ V+ Q + EAA E+ E LS + K T
Sbjct: 963 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMET 1006
Score = 62.9 bits (146), Expect = 3e-09
Identities = 98/474 (20%), Positives = 201/474 (42%), Gaps = 34/474 (7%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITE 245
+E+ + V+ E + K D + L + L +++L + K + +++E
Sbjct: 438 VEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSE 497
Query: 246 TVRVRETSPTTCVV---------RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILND 296
R+ E + R+ + PA D L+ L+E + L V +
Sbjct: 498 KSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDM--SLSLLQEISSLQEKLEVTRTDH 555
Query: 297 SSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK 356
+ TS++ E AR + ++K+ T +K L + L+ L+ ANK N D+ +
Sbjct: 556 QREITSLK-EHFGAREETHQKEIKALYTATEK-LSKENESLKSKLEHANKENSDVI-ALW 612
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQ-YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L+ T I +H + +L+V+ + G L ++E++R +Y+ ++
Sbjct: 613 KSKLE-TAIASH-QQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQH--EIENLQN 668
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
QQ E E+ + L + E L + + D+ + + E E +
Sbjct: 669 QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAE 728
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA--NAIVGGKRIISKLEARIKD 533
V+ L Q + + V + ++K +L +++A A GK + KL +++
Sbjct: 729 IKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEA 788
Query: 534 MELELDE-EKRRHAETIKILR-KKERQLKEV-IIQCEEDQKNISLLQDSLEKTSQKVSIY 590
E ++ E ++AE+ K +E Q +E+ + +E+ +S ++++LEK Q I
Sbjct: 789 AEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQ---IL 845
Query: 591 KRQLAE--QEGMS-----QQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
K + AE +E +S Q++V ++ + + + + NL+ + AK R
Sbjct: 846 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFR 899
Score = 60.9 bits (141), Expect = 1e-08
Identities = 82/388 (21%), Positives = 177/388 (45%), Gaps = 37/388 (9%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQL--NARVVEAET 317
++ T + A D + LN+L+E ++ +DL + +S + +E + +AR+ E E
Sbjct: 412 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQ 471
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNI-DLQKTIKKQSLQLTEIQTHYDEVQRQL 376
L E T+ KLQ ++ + ++ V+ K+ I +L+K + + ++ E++ + +
Sbjct: 472 SLLFEKTK-ADKLQRELEDTRVA-TVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG 529
Query: 377 QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL-RVKRSVEQQYEESQTRVNELTVINVNL 435
V D + I SL ++E R ++++ + +K + E Q + L L
Sbjct: 530 DV--DMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKL 587
Query: 436 SSSKAKIEQELAIVAADYDEI----TKELRIADERYQRVQTELKHTVE-----HLHEEQE 486
S ++ +L + ++ +L A +Q+ ELK + E E
Sbjct: 588 SKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAE 647
Query: 487 RIVKIEAVKKSLEIEVKNI-----SVRLEEVEANAIVGGK--RIISKLEARIKDMELELD 539
+IE ++ + E++N+ S R + + K ++I + E ++ + +LD
Sbjct: 648 LKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLD 707
Query: 540 EEKRRH----AETIKILRKKERQLKEVII---QCEEDQKNISLLQDSLEKTSQK-VSIYK 591
+ + +H +T+ L++ E ++KE+ + +C E K I L+ T +K + +
Sbjct: 708 KAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDA 767
Query: 592 RQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ A EG S+ +++ +++LEAAE
Sbjct: 768 LRKASSEGKSE-----MKKLRQQLEAAE 790
Score = 57.6 bits (133), Expect = 1e-07
Identities = 73/371 (19%), Positives = 167/371 (45%), Gaps = 42/371 (11%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++++L+ V+ D V +LN ++ ++E L RV E E+ K ++ K +I
Sbjct: 409 KMDQLRTMVEAADREKVELLNQLEEEKR-KVEDLQFRV-EEESITKGDLETQTKLEHARI 466
Query: 335 TELELSLDVANKTNID-LQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
ELE SL + KT D LQ+ ++ + ++ E+++ L + + + +RR++S
Sbjct: 467 KELEQSL-LFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLES- 524
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+ G+ + +L + + + E +L V + +++ +
Sbjct: 525 ----NKPAGDVDMSLSLLQEISSLQE-------KLEVTRTDHQREITSLKEHFGAREETH 573
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+ K L A E+ + LK +EH ++E ++ + K LE + + +EE++
Sbjct: 574 QKEIKALYTATEKLSKENESLKSKLEHANKENSDVIAL--WKSKLETAIASHQQAMEELK 631
Query: 514 ANAIVG-GKRI--ISKLEARIKDMELEL-----------DEEKRRH--------AETIKI 551
+ G G ++L+ +I+ M L+ D E+ H A+ +K+
Sbjct: 632 VSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKV 691
Query: 552 LRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
+++KE L+ + + ++ + +++ ++D+L K Q+ I ++L + + +
Sbjct: 692 IKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKL-QEAEIKVKELEVLQAKCNEQTKVIDN 750
Query: 611 FQRELEAAEDR 621
F +L+A E++
Sbjct: 751 FTSQLKATEEK 761
Score = 42.3 bits (95), Expect = 0.005
Identities = 54/252 (21%), Positives = 117/252 (46%), Gaps = 33/252 (13%)
Query: 304 EIEQLNARVVEAETKLKSE-VTRIKKKLQIQITELELSLDVANKTNIDLQK---TIKKQS 359
E+E+L + +A+ +E +I +++ + TE SL+ +TN LQ T+K+ +
Sbjct: 1060 ELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENN 1119
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE 419
L+ E +L + + V ++++ E+E ++ + A + + + E
Sbjct: 1120 LKNVE----------ELNKSKELLTVENQKMEEFRKEIETLK---QAAAQKSQQLSALQE 1166
Query: 420 ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE----LRIADERYQRVQTELK 475
E+ EL ++S + K+E+E +++ E+ K ++ ADE +Q +
Sbjct: 1167 ENVKLAEELGRSRDEVTSHQ-KLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSIS 1225
Query: 476 HTVEHLHEEQERIVKIE---AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
T L E+ + K+ V + K++ ++ +E++ + KLE ++K
Sbjct: 1226 ITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKV--------KLELKVK 1277
Query: 533 DMELELDEEKRR 544
++EL+L E KR+
Sbjct: 1278 NLELQLKENKRQ 1289
Score = 33.9 bits (74), Expect = 1.8
Identities = 52/212 (24%), Positives = 92/212 (43%), Gaps = 27/212 (12%)
Query: 424 RVNELTVINVNLSSSKAKIEQ----------ELAIVAADYDEITKELRIADERYQRVQTE 473
+++ T + L + IEQ E+A + EI +EL +A + + + E
Sbjct: 346 KISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLE 405
Query: 474 LKHTVEHLHEEQERI--VKIEAVKKSLEIEVKNISVRLEEVEANAIV-GGKRIISKLE-A 529
L+ ++ L E K+E + + LE E + + VE +I G +KLE A
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQ-LEEEKRKVEDLQFRVEEESITKGDLETQTKLEHA 464
Query: 530 RIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
RIK++E L EK + K +R+L++ + ++ I L+ L Q+V+
Sbjct: 465 RIKELEQSLLFEKTK-------ADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAE 517
Query: 590 YKRQL-----AEQEGMSQQSVTRVRRFQRELE 616
+R+L A MS + + Q +LE
Sbjct: 518 LRRRLESNKPAGDVDMSLSLLQEISSLQEKLE 549
Score = 31.9 bits (69), Expect = 7.5
Identities = 36/166 (21%), Positives = 72/166 (43%), Gaps = 4/166 (2%)
Query: 471 QTELKHTVEHLHE-EQERIVKIEAVKKS-LEIEVKNISVR-LEEVEANAIVGGKRIISKL 527
+ E+ H+ E EQE + + + LE+E K +R + E V + +
Sbjct: 375 RAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEE 434
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+ +++D++ ++EE + + + ++KE+ ++ LQ LE T
Sbjct: 435 KRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVAT 494
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
K ++ E E V V +R LE+ + DV + +LSL++
Sbjct: 495 VSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDV-DMSLSLLQ 539
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 72.1 bits (169), Expect = 6e-12
Identities = 82/364 (22%), Positives = 160/364 (43%), Gaps = 30/364 (8%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARV----V 313
+ N + IDN + +QL +E + D L S+ + ++E ++ +
Sbjct: 751 KCNEQTKVIDN-FTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEI 809
Query: 314 E--AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
E AE+ S +TR + ++++T L+ +L ++ L+K ++ + E
Sbjct: 810 EKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVS 869
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGN---YEQALRVKRSVEQQY----EESQTR 424
VQR +Q T+++ + + L+ ++E++R N E R K E+Q E+ +
Sbjct: 870 VQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEND 929
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH-TVEHLHE 483
+ E+ ++ + SS K+ EL + D +E+ +L A+E +Q ++ TV+
Sbjct: 930 IAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQS 989
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
+QE K E KK LE ++ ++ ++E +L+AR E E K
Sbjct: 990 QQEAAKKHEEEKKELERKLSDLEKKMETSHNQC--------QELKAR---YERATSETKT 1038
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+H E ++ L+K ++ + E+ N LLQ+ E Q Q AE +
Sbjct: 1039 KHEEILQNLQKTLLDTEDKLKGAREE--NSGLLQELEELRKQADKAKAAQTAEDAMQIME 1096
Query: 604 SVTR 607
+T+
Sbjct: 1097 QMTK 1100
Score = 64.9 bits (151), Expect = 9e-10
Identities = 100/524 (19%), Positives = 222/524 (42%), Gaps = 41/524 (7%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+K R+ E+EK+L L +EV +ELR++ + ++ +LL+E + + +
Sbjct: 508 EKSRIMELEKDLALRVQEV---AELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRT 564
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
D Q T + +++ + K + S+ ES+ + + +
Sbjct: 565 DHQREITSL-KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALW 623
Query: 262 NTELPAIDNSYLNQLNELKET--------VKQFDDLSVYI----LNDSSKQTSIEIEQLN 309
++L S+ + ELK + +F +L I L+ + +++ +Q +
Sbjct: 624 KSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDS 683
Query: 310 ARVVEAE--TKLKSEVTRIKKKLQIQITELELSLDVANKTN-IDLQKTIKK---QSLQLT 363
R A+ L++++ ++ K+ + + + LD A + ++++ T+ K +++
Sbjct: 684 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 743
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E++ + Q +V +D + + + +++ +R + + + QQ E ++
Sbjct: 744 ELEVLQAKCNEQTKV-IDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEK 802
Query: 424 RVNELTVINVNLSSSKA-KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ L I N SSKA I +EL + + L + + ++ EL+ E
Sbjct: 803 QIKHLE-IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFA 861
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E E V +V++S++ V + +E + N + + KL + DME + E+
Sbjct: 862 EASEEAV---SVQRSMQETVNKL--HQKEEQFNMLSSD---LEKLRENLADMEAKFREKD 913
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL---EKTSQKVSIYKRQLAEQEG 599
R + IK K E + E++ ++ ++ + D L E+ +++ + + E
Sbjct: 914 EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS 973
Query: 600 MSQQSV--TRVRRFQRELEAA---EDRADVAESNLSLIRAKHRT 638
Q+S+ V+ Q + EAA E+ E LS + K T
Sbjct: 974 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMET 1017
Score = 57.6 bits (133), Expect = 1e-07
Identities = 74/387 (19%), Positives = 173/387 (44%), Gaps = 51/387 (13%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ T + A D + LN+L+E ++ +DL Q +E E + +E ++++
Sbjct: 412 QLRTMVEAADREKVELLNQLEEEKRKVEDL----------QFRVEEESITKGDLEQKSQI 461
Query: 320 KSEVTRIKKKLQ-IQITELELSLDVANKTNID-LQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ + KL+ +I ELE SL + KT D LQ+ ++ + ++ E+++ L
Sbjct: 462 SEDPENTQTKLEHARIKELEQSL-LFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLA 520
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+ + + +RR++S + G+ + +L + + + E +L V +
Sbjct: 521 LRVQEVAELRRRLES-----NKPAGDVDMSLSLLQEISSLQE-------KLEVTRTDHQR 568
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+++ + + K L A E+ + LK +EH ++E ++ + K
Sbjct: 569 EITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIAL--WKSK 626
Query: 498 LEIEVKNISVRLEEVEANAIVG-GKRI--ISKLEARIKDMELEL-----------DEEKR 543
LE + + +EE++ + G G ++L+ +I+ M L+ D E+
Sbjct: 627 LETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERA 686
Query: 544 RH--------AETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQL 594
H A+ +K++++KE L+ + + ++ + +++ ++D+L K Q+ I ++L
Sbjct: 687 AHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKL-QEAEIKVKEL 745
Query: 595 AEQEGMSQQSVTRVRRFQRELEAAEDR 621
+ + + F +L+A E++
Sbjct: 746 EVLQAKCNEQTKVIDNFTSQLKATEEK 772
Score = 42.3 bits (95), Expect = 0.005
Identities = 54/252 (21%), Positives = 117/252 (46%), Gaps = 33/252 (13%)
Query: 304 EIEQLNARVVEAETKLKSE-VTRIKKKLQIQITELELSLDVANKTNIDLQK---TIKKQS 359
E+E+L + +A+ +E +I +++ + TE SL+ +TN LQ T+K+ +
Sbjct: 1071 ELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENN 1130
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE 419
L+ E +L + + V ++++ E+E ++ + A + + + E
Sbjct: 1131 LKNVE----------ELNKSKELLTVENQKMEEFRKEIETLK---QAAAQKSQQLSALQE 1177
Query: 420 ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE----LRIADERYQRVQTELK 475
E+ EL ++S + K+E+E +++ E+ K ++ ADE +Q +
Sbjct: 1178 ENVKLAEELGRSRDEVTSHQ-KLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSIS 1236
Query: 476 HTVEHLHEEQERIVKIE---AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
T L E+ + K+ V + K++ ++ +E++ + KLE ++K
Sbjct: 1237 ITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKV--------KLELKVK 1288
Query: 533 DMELELDEEKRR 544
++EL+L E KR+
Sbjct: 1289 NLELQLKENKRQ 1300
Score = 32.3 bits (70), Expect = 5.6
Identities = 44/214 (20%), Positives = 91/214 (42%), Gaps = 13/214 (6%)
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
+++ T + L + IEQ LA + E+ K E Q + +H+ E
Sbjct: 346 KISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLE 405
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMEL---ELDE 540
+ ++ ++ + ++ + E + +LEE KR + L+ R+++ + +L++
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQLEE--------EKRKVEDLQFRVEEESITKGDLEQ 457
Query: 541 EKRRHAETIKILRKKER-QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+ + + K E ++KE+ ++ LQ LE T K ++ E E
Sbjct: 458 KSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEK 517
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
V V +R LE+ + DV + +LSL++
Sbjct: 518 DLALRVQEVAELRRRLESNKPAGDV-DMSLSLLQ 550
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 70.5 bits (165), Expect = 2e-11
Identities = 81/364 (22%), Positives = 159/364 (43%), Gaps = 30/364 (8%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARV----V 313
+ N + IDN + +QL +E + D L S+ + ++E ++ +
Sbjct: 751 KCNEQTKVIDN-FTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEI 809
Query: 314 E--AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
E AE+ S +TR + ++++T L+ +L ++ L+K ++ + E
Sbjct: 810 EKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVS 869
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGN---YEQALRVKRSVEQQY----EESQTR 424
VQR +Q T+++ + + L+ ++E++R N E R K E+Q E+ +
Sbjct: 870 VQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEND 929
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH-TVEHLHE 483
+ E+ ++ + S K+ EL + D +E+ +L A+E +Q ++ TV+
Sbjct: 930 IAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQS 989
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKR 543
+QE K E KK LE ++ ++ ++E +L+AR E E K
Sbjct: 990 QQEAAKKHEEEKKELERKLSDLEKKMETSHNQC--------QELKAR---YERATSETKT 1038
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+H E ++ L+K ++ + E+ N LLQ+ E Q Q AE +
Sbjct: 1039 KHEEILQNLQKTLLDTEDKLKGAREE--NSGLLQELEELRKQAEKAKAAQTAEDAMQIME 1096
Query: 604 SVTR 607
+T+
Sbjct: 1097 QMTK 1100
Score = 64.5 bits (150), Expect = 1e-09
Identities = 100/524 (19%), Positives = 222/524 (42%), Gaps = 41/524 (7%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+K R+ E+EK+L L +EV +ELR++ + ++ +LL+E + + +
Sbjct: 508 EKSRIMELEKDLALRVQEV---AELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRT 564
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
D Q T + +++ + K + S+ ES+ + + +
Sbjct: 565 DHQREITSL-KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALW 623
Query: 262 NTELPAIDNSYLNQLNELKET--------VKQFDDLSVYI----LNDSSKQTSIEIEQLN 309
++L S+ + ELK + +F +L I L+ + +++ +Q +
Sbjct: 624 KSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDS 683
Query: 310 ARVVEAE--TKLKSEVTRIKKKLQIQITELELSLDVANKTN-IDLQKTIKK---QSLQLT 363
R A+ L++++ ++ K+ + + + LD A + ++++ T+ K +++
Sbjct: 684 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 743
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E++ + Q +V +D + + + +++ +R + + + QQ E ++
Sbjct: 744 ELEVLQAKCNEQTKV-IDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEK 802
Query: 424 RVNELTVINVNLSSSKA-KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ L I N SSKA I +EL + + L + + ++ EL+ E
Sbjct: 803 QIKHLE-IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFA 861
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E E V +V++S++ V + +E + N + + KL + DME + E+
Sbjct: 862 EASEEAV---SVQRSMQETVNKL--HQKEEQFNMLSSD---LEKLRENLADMEAKFREKD 913
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL---EKTSQKVSIYKRQLAEQEG 599
R + IK K E + E++ ++ ++ + D L E+ +++ + + E
Sbjct: 914 EREEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENAS 973
Query: 600 MSQQSV--TRVRRFQRELEAA---EDRADVAESNLSLIRAKHRT 638
Q+S+ V+ Q + EAA E+ E LS + K T
Sbjct: 974 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMET 1017
Score = 57.6 bits (133), Expect = 1e-07
Identities = 74/387 (19%), Positives = 173/387 (44%), Gaps = 51/387 (13%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ T + A D + LN+L+E ++ +DL Q +E E + +E ++++
Sbjct: 412 QLRTMVEAADREKVELLNQLEEEKRKVEDL----------QFRVEEESITKGDLEQKSQI 461
Query: 320 KSEVTRIKKKLQ-IQITELELSLDVANKTNID-LQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+ + KL+ +I ELE SL + KT D LQ+ ++ + ++ E+++ L
Sbjct: 462 SEDPENTQTKLEHARIKELEQSL-LFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLA 520
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+ + + +RR++S + G+ + +L + + + E +L V +
Sbjct: 521 LRVQEVAELRRRLES-----NKPAGDVDMSLSLLQEISSLQE-------KLEVTRTDHQR 568
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+++ + + K L A E+ + LK +EH ++E ++ + K
Sbjct: 569 EITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIAL--WKSK 626
Query: 498 LEIEVKNISVRLEEVEANAIVG-GKRI--ISKLEARIKDMELEL-----------DEEKR 543
LE + + +EE++ + G G ++L+ +I+ M L+ D E+
Sbjct: 627 LETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERA 686
Query: 544 RH--------AETIKILRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQL 594
H A+ +K++++KE L+ + + ++ + +++ ++D+L K Q+ I ++L
Sbjct: 687 AHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKL-QEAEIKVKEL 745
Query: 595 AEQEGMSQQSVTRVRRFQRELEAAEDR 621
+ + + F +L+A E++
Sbjct: 746 EVLQAKCNEQTKVIDNFTSQLKATEEK 772
Score = 42.7 bits (96), Expect = 0.004
Identities = 54/252 (21%), Positives = 117/252 (46%), Gaps = 33/252 (13%)
Query: 304 EIEQLNARVVEAETKLKSE-VTRIKKKLQIQITELELSLDVANKTNIDLQK---TIKKQS 359
E+E+L + +A+ +E +I +++ + TE SL+ +TN LQ T+K+ +
Sbjct: 1071 ELEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENN 1130
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE 419
L+ E +L + + V ++++ E+E ++ + A + + + E
Sbjct: 1131 LKNVE----------ELNKSKELLTVENQKMEEFRKEIETLK---QAAAQKSQQLSALQE 1177
Query: 420 ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE----LRIADERYQRVQTELK 475
E+ EL ++S + K+E+E +++ E+ K ++ ADE +Q +
Sbjct: 1178 ENVKLAEELGRSRDEVTSHQ-KLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSIS 1236
Query: 476 HTVEHLHEEQERIVKIE---AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
T L E+ + K+ V + K++ ++ +E++ + KLE ++K
Sbjct: 1237 ITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKV--------KLELKVK 1288
Query: 533 DMELELDEEKRR 544
++EL+L E KR+
Sbjct: 1289 NLELQLKENKRQ 1300
Score = 32.3 bits (70), Expect = 5.6
Identities = 44/214 (20%), Positives = 91/214 (42%), Gaps = 13/214 (6%)
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
+++ T + L + IEQ LA + E+ K E Q + +H+ E
Sbjct: 346 KISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLE 405
Query: 484 EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMEL---ELDE 540
+ ++ ++ + ++ + E + +LEE KR + L+ R+++ + +L++
Sbjct: 406 LEAKMDQLRTMVEAADREKVELLNQLEE--------EKRKVEDLQFRVEEESITKGDLEQ 457
Query: 541 EKRRHAETIKILRKKER-QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+ + + K E ++KE+ ++ LQ LE T K ++ E E
Sbjct: 458 KSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEK 517
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
V V +R LE+ + DV + +LSL++
Sbjct: 518 DLALRVQEVAELRRRLESNKPAGDV-DMSLSLLQ 550
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 70.5 bits (165), Expect = 2e-11
Identities = 70/301 (23%), Positives = 135/301 (44%), Gaps = 21/301 (6%)
Query: 315 AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR 374
AE+ S +TR + ++++T L+ +L ++ L+K ++ + E VQR
Sbjct: 767 AESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQR 826
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGN---YEQALRVKRSVEQQY----EESQTRVNE 427
+Q T+++ + + L+ ++E++R N E R K E+Q E+ + + E
Sbjct: 827 SMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAE 886
Query: 428 LTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH-TVEHLHEEQE 486
+ ++ + SS K+ EL + D +E+ +L A+E +Q ++ TV+ +QE
Sbjct: 887 IMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQE 946
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
K E KK LE ++ ++ ++E +L+AR E E K +H
Sbjct: 947 AAKKHEEEKKELERKLSDLEKKMETSHNQC--------QELKAR---YERATSETKTKHE 995
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
E ++ L+K ++ + E+ N LLQ+ E Q Q AE + +T
Sbjct: 996 EILQNLQKTLLDTEDKLKGAREE--NSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMT 1053
Query: 607 R 607
+
Sbjct: 1054 K 1054
Score = 65.7 bits (153), Expect = 5e-10
Identities = 100/524 (19%), Positives = 222/524 (42%), Gaps = 41/524 (7%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+K R+ E+EK+L L +EV +ELR++ + ++ +LL+E + + +
Sbjct: 462 EKSRIMELEKDLALRVQEV---AELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRT 518
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
D Q T + +++ + K + S+ ES+ + + +
Sbjct: 519 DHQREITSL-KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALW 577
Query: 262 NTELPAIDNSYLNQLNELKET--------VKQFDDLSVYI----LNDSSKQTSIEIEQLN 309
++L S+ + ELK + +F +L I L+ + +++ +Q +
Sbjct: 578 KSKLETAIASHQQAMEELKVSFSKGLGAETAEFAELKTQIEKMRLDYQHEIENLQNQQNS 637
Query: 310 ARVVEAE--TKLKSEVTRIKKKLQIQITELELSLDVANKTN-IDLQKTIKK---QSLQLT 363
R A+ L++++ ++ K+ + + + LD A + ++++ T+ K +++
Sbjct: 638 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 697
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E++ + Q +V +D + + + +++ +R + + + QQ E ++
Sbjct: 698 ELEVLQAKCNEQTKV-IDNFTSQPKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEK 756
Query: 424 RVNELTVINVNLSSSKA-KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
++ L I N SSKA I +EL + + L + + ++ EL+ E
Sbjct: 757 QIKHLE-IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFA 815
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E E V +V++S++ V + +E + N + + KL + DME + E+
Sbjct: 816 EASEEAV---SVQRSMQETVNKL--HQKEEQFNMLSSD---LEKLRENLADMEAKFREKD 867
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL---EKTSQKVSIYKRQLAEQEG 599
R + IK K E + E++ ++ ++ + D L E+ +++ + + E
Sbjct: 868 EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS 927
Query: 600 MSQQSV--TRVRRFQRELEAA---EDRADVAESNLSLIRAKHRT 638
Q+S+ V+ Q + EAA E+ E LS + K T
Sbjct: 928 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMET 971
Score = 64.1 bits (149), Expect = 2e-09
Identities = 75/388 (19%), Positives = 166/388 (42%), Gaps = 22/388 (5%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN--ARVVEAET 317
++ T + A D + LN+L+E ++ +DL + +S + +E+ ++ +R++E E
Sbjct: 412 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEK 471
Query: 318 KLK---SEVTRIKKKLQIQ--ITELELSLDVANKTNI---DLQKTIKKQSLQLTEIQTHY 369
L EV ++++L+ ++++SL + + + L+ T ++T ++ H+
Sbjct: 472 DLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHF 531
Query: 370 ----DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV-KRSVEQQYEESQTR 424
+ Q++++ + +SL ++E + + K +E Q
Sbjct: 532 GAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQA 591
Query: 425 VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
+ EL V+ S E A + +++ + + E Q Q H E
Sbjct: 592 MEEL---KVSFSKGLGAETAEFAELKTQIEKMRLDYQHEIENLQNQQN--SERAAHAKEM 646
Query: 485 QERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL-EARIKDMELELDEEK- 542
+ K+ V K E ++ I +L++ E +V + ++KL EA IK ELE+ + K
Sbjct: 647 EALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKC 706
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ I + + +E ++ + +K S + ++K Q++ ++Q+ E
Sbjct: 707 NEQTKVIDNFTSQPKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKN 766
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLS 630
++ REL+ E + + NLS
Sbjct: 767 AESSKASSITRELQGRELKLTNLQENLS 794
Score = 52.4 bits (120), Expect = 5e-06
Identities = 62/304 (20%), Positives = 144/304 (47%), Gaps = 17/304 (5%)
Query: 269 DNSYLNQLN-ELKETVKQFDDLSVYIL--NDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
++S L ++N EL+ + ++L + + N+++ IE + + +++ + +
Sbjct: 894 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 953
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL----D 381
KK+L+ ++++LE ++ ++ +L+ ++ + +E +T ++E+ + LQ TL D
Sbjct: 954 EKKELERKLSDLEKKMETSHNQCQELKARYERAT---SETKTKHEEILQNLQKTLLDTED 1010
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE-QQYEESQTRVNELTVINV-NLSSSK 439
+ A+ L E+EE+R ++A + + + Q E T+ T+ ++ + +
Sbjct: 1011 KLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTN 1070
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
AK++ EL + + + +EL + E + T +E +E E + + A K
Sbjct: 1071 AKLQNELDTLKENNLKNVEELNKSKE----LLTVENQKMEEFRKEIETLKQAAAQKSQQL 1126
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
++ +V+L E E KLE + +L E K+R ++ IK +++ L
Sbjct: 1127 SALQEENVKLAE-ELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1185
Query: 560 KEVI 563
++ I
Sbjct: 1186 QKSI 1189
Score = 42.3 bits (95), Expect = 0.005
Identities = 54/252 (21%), Positives = 117/252 (46%), Gaps = 33/252 (13%)
Query: 304 EIEQLNARVVEAETKLKSE-VTRIKKKLQIQITELELSLDVANKTNIDLQK---TIKKQS 359
E+E+L + +A+ +E +I +++ + TE SL+ +TN LQ T+K+ +
Sbjct: 1025 ELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENN 1084
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE 419
L+ E +L + + V ++++ E+E ++ + A + + + E
Sbjct: 1085 LKNVE----------ELNKSKELLTVENQKMEEFRKEIETLK---QAAAQKSQQLSALQE 1131
Query: 420 ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKE----LRIADERYQRVQTELK 475
E+ EL ++S + K+E+E +++ E+ K ++ ADE +Q +
Sbjct: 1132 ENVKLAEELGRSRDEVTSHQ-KLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSIS 1190
Query: 476 HTVEHLHEEQERIVKIE---AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
T L E+ + K+ V + K++ ++ +E++ + KLE ++K
Sbjct: 1191 ITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKV--------KLELKVK 1242
Query: 533 DMELELDEEKRR 544
++EL+L E KR+
Sbjct: 1243 NLELQLKENKRQ 1254
Score = 35.5 bits (78), Expect = 0.61
Identities = 58/269 (21%), Positives = 106/269 (39%), Gaps = 31/269 (11%)
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN-------VNLSSSKAKIEQ 444
S TG + E Y + + ++++ +E Q + +L +S +IEQ
Sbjct: 331 SRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQ 390
Query: 445 ELAI-----------VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
ELA+ + A D++ + AD + +L+ + + Q R+ +
Sbjct: 391 ELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESI 450
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVG-------GKRIISKLEARIKDMELELDEEKRRHA 546
K LE+ + R+ E+E + + +R+ S A DM L L +E
Sbjct: 451 TKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQ 510
Query: 547 ETIKILRKKERQ----LKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
E +++ R ++ LKE EE QK I L + EK S++ K +L E
Sbjct: 511 EKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKL-EHANKE 569
Query: 602 QQSVTRVRRFQRELEAAEDRADVAESNLS 630
V + + + E A + + E +S
Sbjct: 570 NSDVIALWKSKLETAIASHQQAMEELKVS 598
>Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.
Length = 2101
Score = 70.1 bits (164), Expect = 2e-11
Identities = 91/439 (20%), Positives = 183/439 (41%), Gaps = 30/439 (6%)
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
Q ++ L R + K L+ + + ++ S S+ E + + + T V + +
Sbjct: 446 QEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTS 505
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI------EIEQLNARVVEAET 317
EL ++ + Q EL +Q + + +Q ++EQL++ + + E
Sbjct: 506 ELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ 565
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+LK + + Q +L + + + + +K+ E + +Q+QLQ
Sbjct: 566 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQ 625
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
V + AQ + E E+ E+ + Q+ E+Q +V EL + L S
Sbjct: 626 VANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL---ELQLRS 682
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQ----RVQTELKHTVEHLHEEQERIVKIEA 493
+ K E VA + D++ ++L+ E + ++ E + + L E+Q I +++A
Sbjct: 683 EQQK-ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKA 741
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETI-KIL 552
+SL + K LEE A G++ LEAR+ L+L E + E + + L
Sbjct: 742 ETRSLVEQHKRERKELEEERA-----GRK---GLEARL----LQLGEAHQAETEVLRREL 789
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQ 612
+ +CE+ K ++ +D E + Q+ + Y EQ ++ + R
Sbjct: 790 AEAMAAQHTAESECEQLVKEVAAWRDGYEDSQQEEAQYGAMFQEQLMTLKEECEKAR--- 846
Query: 613 RELEAAEDRADVAESNLSL 631
+EL+ A+++ ES+ L
Sbjct: 847 QELQEAKEKVAGIESHSEL 865
Score = 64.1 bits (149), Expect = 2e-09
Identities = 69/362 (19%), Positives = 154/362 (42%), Gaps = 11/362 (3%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
+ L + ++ +K+ + D ++Q + E+ A + E + LK ++ ++K+ +
Sbjct: 558 SSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK-QLEALEKEKAAK 616
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ L+ L VAN+ Q ++ + + E+ +E+Q ++ + AQ ++ L
Sbjct: 617 LEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL 676
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++ + + RV + +Q E+ Q L V +L K + L
Sbjct: 677 ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCI 736
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
E+ E R E+++R + EL+ + R++++ ++ E EV L
Sbjct: 737 SELKAETRSLVEQHKRERKELEEERAGRKGLEARLLQLGEAHQA-ETEV------LRREL 789
Query: 514 ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNI 573
A A+ S+ E +K++ D + E + + QL + +CE+ ++
Sbjct: 790 AEAMAAQHTAESECEQLVKEVAAWRDGYEDSQQEEAQYGAMFQEQLMTLKEECEKARQE- 848
Query: 574 SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
LQ++ EK + S + Q++ Q+ + + R ++++ E RA +LS ++
Sbjct: 849 --LQEAKEKVAGIESHSELQISRQQNKLAELHANLARALQQVQEKEVRAQKLADDLSTLQ 906
Query: 634 AK 635
K
Sbjct: 907 EK 908
Score = 48.8 bits (111), Expect = 6e-05
Identities = 52/253 (20%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 391 QSLTGEVEEIRGNYEQALRVKRS-----VEQQYEESQTRVNELTVINVNLSSSKAKI--- 442
Q L E+++ R Y Q L R+ + + E+Q+ EL V+ +K K+
Sbjct: 1463 QFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEE 1522
Query: 443 ----EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
++E + A +E++K+L +D+ + Q +LK E Q+ + +A L
Sbjct: 1523 RQRFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRFQAQLNEL 1582
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
+ ++ E + ++ + +A+ K EL E+ R +++ L+K+ ++
Sbjct: 1583 QAQLSQKEQAAEHYKLQM----EKAKTHYDAK-KQQNQELQEQLR----SLEQLQKENKE 1633
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
L+ + + + L E+T + ++ R L Q + Q + + +FQ +A
Sbjct: 1634 LRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDAL 1693
Query: 619 EDRADVAESNLSL 631
+ R A+ L L
Sbjct: 1694 KSREPQAKPQLDL 1706
Score = 48.4 bits (110), Expect = 8e-05
Identities = 88/422 (20%), Positives = 176/422 (41%), Gaps = 45/422 (10%)
Query: 273 LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQI 332
L Q +LK T K D + L++ + S ++ + + + + + L +E+T K
Sbjct: 296 LKQCQDLK-TEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDAL-NELTEEHSKATQ 353
Query: 333 QITELELSLDVANKTNIDLQKTI--KKQSLQ--LTEIQTHYDEVQRQ------------L 376
+ E + L+ + +K + K + LQ L++++ H ++Q L
Sbjct: 354 EWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVL 413
Query: 377 QV-TLDQYGVA----QRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTV 430
Q+ TL Q ++Q+ +E RG E L +R E++ ++ + + +L
Sbjct: 414 QLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQS 473
Query: 431 INVNLSSSKAKIEQEL----AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQE 486
NLS +K ++EQ A + A +T EL + Q+ EL + E+Q
Sbjct: 474 SISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQA 533
Query: 487 RIVKI----EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++ + E + L +V+ +S L++ E K + K EA +D +L
Sbjct: 534 QLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQL----KEVAEKQEATRQDHAQQLATAA 589
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ LR+++ LK++ +E + +LQ L+ ++ + + + +
Sbjct: 590 EEREAS---LRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKA 646
Query: 603 QSVTRVRRFQRELEAA-----EDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESR 657
+ +V Q +E A E +A VAE L L R++ + V + L ++ +
Sbjct: 647 ELSRKVEELQACVETARQEQHEAQAQVAELELQL-RSEQQKATEKERVAQEKDQLQEQLQ 705
Query: 658 AL 659
AL
Sbjct: 706 AL 707
Score = 37.5 bits (83), Expect = 0.15
Identities = 38/196 (19%), Positives = 88/196 (44%), Gaps = 16/196 (8%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK------QTSIEIEQLNARVVEAE 316
T L + + EL+ +++ V +L + + + + ++E+L+ ++ +++
Sbjct: 1489 TRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADSD 1548
Query: 317 TKLKSEVTRIKK-KLQIQITELELSLDVANKTNIDLQKTIKKQS-----LQLTEIQTHYD 370
K + ++K + Q ++ E A + Q + K+Q+ LQ+ + +THYD
Sbjct: 1549 QASKVQQQKLKAVQAQGGESQQEAQRFQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYD 1608
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV 430
++Q Q +Q R ++ L E +E+R E+ + + +E++ LT
Sbjct: 1609 AKKQQNQELQEQL----RSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTA 1664
Query: 431 INVNLSSSKAKIEQEL 446
+L + A +Q+L
Sbjct: 1665 QVRSLEAQVAHADQQL 1680
Score = 36.7 bits (81), Expect = 0.26
Identities = 51/274 (18%), Positives = 112/274 (40%), Gaps = 8/274 (2%)
Query: 351 LQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV 410
L+ + K Q + Q D ++R L+ +++L G++EE +
Sbjct: 1125 LRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSA 1184
Query: 411 KRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
S +++ +T+V + + + A+ QE + + +E+ I + +
Sbjct: 1185 LASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEK 1244
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLEA 529
+ E K + E E+ K+E +S + + E++ A++ G+R S EA
Sbjct: 1245 EGESKELKRLVMAESEKSQKLE---ESCACCRQRQPATVPELQNAALLCGRRCRASGREA 1301
Query: 530 RIKDMELE-LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
+ + E L +E AE + L ++ + +E Q E+ + L S + ++
Sbjct: 1302 EKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSEL- 1360
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
+ + L +Q + + +R + ELE ++ A
Sbjct: 1361 LPAKHLCQQ--LQAEQAAAEKRHREELEQSKQAA 1392
Score = 35.1 bits (77), Expect = 0.80
Identities = 50/307 (16%), Positives = 124/307 (40%), Gaps = 14/307 (4%)
Query: 168 QKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVN-RDYTNLSKNVLAKAL 226
++ A G + + L+E S+ Q ER + A T R +L+ A+A
Sbjct: 971 EREAEQMGNELERLRAALME-SQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAE 1029
Query: 227 MESKAMNSCDSRVTESIT-ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQ 285
+E + N+ + + E T + + + +L ++ + + +L EL++TVKQ
Sbjct: 1030 LEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQ 1089
Query: 286 FDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIK-KKLQIQITELELSLDVA 344
+ + E E + ++E ++E T K + L+ ++++LE
Sbjct: 1090 LKE----------QLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQ 1139
Query: 345 NKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY 404
+ L+++++ + E + + +Q QL+ + G +Q + S E+ R
Sbjct: 1140 QEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKV 1199
Query: 405 EQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + + + Q + + +L + + +++ + E+ + +
Sbjct: 1200 QDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAES 1259
Query: 465 ERYQRVQ 471
E+ Q+++
Sbjct: 1260 EKSQKLE 1266
Score = 34.3 bits (75), Expect = 1.4
Identities = 44/194 (22%), Positives = 86/194 (44%), Gaps = 11/194 (5%)
Query: 451 ADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI-VKIEAVKKSLEIEVKNISVR- 508
A+ + ++LR Y + LK L EE + + ++ LE+E+ +
Sbjct: 1417 AEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKY 1476
Query: 509 LEEVEANAIVGGKRIIS-KLEARIKDMELELDEEKRRHAETIKILRKKER---QLKEVII 564
++E+ A R+ + EA+ ELE+ K A+ +K+L +++R + +++
Sbjct: 1477 VQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAK-VKVLEERQRFQEERQKLTA 1535
Query: 565 QCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADV 624
Q EE K ++ + + QK+ + + Q G SQQ R + EL+A + +
Sbjct: 1536 QVEELSKKLADSDQASKVQQQKL----KAVQAQGGESQQEAQRFQAQLNELQAQLSQKEQ 1591
Query: 625 AESNLSLIRAKHRT 638
A + L K +T
Sbjct: 1592 AAEHYKLQMEKAKT 1605
>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
Length = 2115
Score = 70.1 bits (164), Expect = 2e-11
Identities = 88/438 (20%), Positives = 182/438 (41%), Gaps = 28/438 (6%)
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
Q ++ L R + K L+ + + ++ S S+ E + + + T V + +
Sbjct: 446 QEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTS 505
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI------EIEQLNARVVEAET 317
EL ++ + Q EL +Q + + +Q ++EQL++ + + E
Sbjct: 506 ELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ 565
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+LK + + Q +L + + + + +K+ E + +Q+QLQ
Sbjct: 566 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQ 625
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
V + AQ + E E+ E+ + Q+ E+Q +V EL + L S
Sbjct: 626 VANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL---ELQLRS 682
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQ----RVQTELKHTVEHLHEEQERIVKIEA 493
+ K E VA + D++ ++L+ E + ++ E + + L E+Q I +++A
Sbjct: 683 EQQK-ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKA 741
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILR 553
+SL + K LEE A G K + ++L+ + + E + +R AE +
Sbjct: 742 ETRSLVEQHKRERKELEEERA----GRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQH 797
Query: 554 KKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR 613
E +CE+ K ++ ++ E + Q+ + Y EQ ++ + R +
Sbjct: 798 TAES-------ECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKAR---Q 847
Query: 614 ELEAAEDRADVAESNLSL 631
EL+ A+++ ES+ L
Sbjct: 848 ELQEAKEKVAGIESHSEL 865
Score = 62.1 bits (144), Expect = 6e-09
Identities = 71/363 (19%), Positives = 154/363 (42%), Gaps = 13/363 (3%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
+ L + ++ +K+ + D ++Q + E+ A + E + LK ++ ++K+ +
Sbjct: 558 SSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK-QLEALEKEKAAK 616
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ L+ L VAN+ Q ++ + + E+ +E+Q ++ + AQ ++ L
Sbjct: 617 LEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL 676
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++ + + RV + +Q E+ Q L V +L K + L
Sbjct: 677 ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCI 736
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNISVRLEEV 512
E+ E R E+++R + EL+ EE+ +EA + L E V E+
Sbjct: 737 SELKAETRSLVEQHKRERKELE-------EERAGRKGLEARLQQLGEAHQAETEVLRREL 789
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
A A+ S+ E +K++ + + E + + QL + +CE+ ++
Sbjct: 790 -AEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQE 848
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
LQ++ EK + S + Q++ Q+ + + R ++++ E RA +LS +
Sbjct: 849 ---LQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTL 905
Query: 633 RAK 635
+ K
Sbjct: 906 QEK 908
Score = 48.4 bits (110), Expect = 8e-05
Identities = 88/422 (20%), Positives = 176/422 (41%), Gaps = 45/422 (10%)
Query: 273 LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQI 332
L Q +LK T K D + L++ + S ++ + + + + + L +E+T K
Sbjct: 296 LKQCQDLK-TEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDAL-NELTEEHSKATQ 353
Query: 333 QITELELSLDVANKTNIDLQKTI--KKQSLQ--LTEIQTHYDEVQRQ------------L 376
+ E + L+ + +K + K + LQ L++++ H ++Q L
Sbjct: 354 EWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVL 413
Query: 377 QV-TLDQYGVA----QRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTV 430
Q+ TL Q ++Q+ +E RG E L +R E++ ++ + + +L
Sbjct: 414 QLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQS 473
Query: 431 INVNLSSSKAKIEQEL----AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQE 486
NLS +K ++EQ A + A +T EL + Q+ EL + E+Q
Sbjct: 474 SISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQA 533
Query: 487 RIVKI----EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++ + E + L +V+ +S L++ E K + K EA +D +L
Sbjct: 534 QLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQL----KEVAEKQEATRQDHAQQLATAA 589
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ LR+++ LK++ +E + +LQ L+ ++ + + + +
Sbjct: 590 EEREAS---LRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKA 646
Query: 603 QSVTRVRRFQRELEAA-----EDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESR 657
+ +V Q +E A E +A VAE L L R++ + V + L ++ +
Sbjct: 647 ELSRKVEELQACVETARQEQHEAQAQVAELELQL-RSEQQKATEKERVAQEKDQLQEQLQ 705
Query: 658 AL 659
AL
Sbjct: 706 AL 707
Score = 46.4 bits (105), Expect = 3e-04
Identities = 67/334 (20%), Positives = 143/334 (42%), Gaps = 27/334 (8%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDL--QKTIKKQSLQ 361
E+ L +V E E + ++ K Q++ L+ + + + N L + + +Q L+
Sbjct: 1408 ELIPLRQKVAEQE-RTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLE 1466
Query: 362 LTEIQTHYDEVQRQLQVTLD---QYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQ 417
+ Q VQ V D + QR QS E+E + YE A ++V ++
Sbjct: 1467 VELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1526
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHT 477
EE Q ++ + V + K +EL+ AD D+ +K + ++ + VQ + +
Sbjct: 1527 QEERQKLTAQVEQLEV-FQREQTKQVEELSKKLADSDQASK---VQQQKLKAVQAQGGES 1582
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE 537
+ Q ++ +++A E ++ +++E+ + + +A+ K E
Sbjct: 1583 QQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH-----------YDAK-KQQNQE 1630
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
L E+ R +++ L+K+ ++L+ + + + L E+T + ++ R L Q
Sbjct: 1631 LQEQLR----SLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQ 1686
Query: 598 EGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
+ Q + + +FQ +A + R A+ L L
Sbjct: 1687 VAHADQQLRDLGKFQVATDALKSREPQAKPQLDL 1720
Score = 42.7 bits (96), Expect = 0.004
Identities = 84/500 (16%), Positives = 195/500 (39%), Gaps = 24/500 (4%)
Query: 168 QKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVN-RDYTNLSKNVLAKAL 226
++ A G + + L+E S+ Q ER + A T R +L+ A+A
Sbjct: 971 EREAEQMGNELERLRAALME-SQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAE 1029
Query: 227 MESKAMNSCDSRVTESIT-ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQ 285
+E + N+ + + E T + + + +L ++ + + +L EL++TVKQ
Sbjct: 1030 LEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQ 1089
Query: 286 FDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIK-KKLQIQITELELSLDVA 344
+ + E E + ++E ++E T K + L+ ++++LE
Sbjct: 1090 LKE----------QLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQ 1139
Query: 345 NKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY 404
+ L+++++ + E + + +Q QL+ + G +Q + S E+ R
Sbjct: 1140 QEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKV 1199
Query: 405 EQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + + + Q + + +L + + +++ + E+ + +
Sbjct: 1200 QDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAES 1259
Query: 465 ERYQRVQTELK----HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGG 520
E+ Q+++ L+ T + ER + +SL E + V E +
Sbjct: 1260 EKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQA 1319
Query: 521 KRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL 580
+R +L +K + E +K + T+++ + L ++ + + + Q +
Sbjct: 1320 ER-AEELGQELKAWQ-EKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAA 1377
Query: 581 EKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFV 640
EK ++ +Q A G + + R +R EL + E +RA+ ++
Sbjct: 1378 EKRHREELEQSKQAA---GGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYA 1434
Query: 641 -TTSTVPGSQVYLVQESRAL 659
S + + L +E+R L
Sbjct: 1435 EQLSMLKKAHGLLAEENRGL 1454
Score = 41.9 bits (94), Expect = 0.007
Identities = 41/167 (24%), Positives = 80/167 (47%), Gaps = 17/167 (10%)
Query: 280 KETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELEL 339
+E KQ ++LS L DS + + ++ ++L A V+A+ E + ++LQ Q+ EL+
Sbjct: 1545 REQTKQVEELSKK-LADSDQASKVQQQKLKA--VQAQG---GESQQEAQRLQAQLNELQA 1598
Query: 340 SLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEE 399
L ++ + LQ+ + +THYD ++Q Q +Q R ++ L E +E
Sbjct: 1599 QLS-------QKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQL----RSLEQLQKENKE 1647
Query: 400 IRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
+R E+ + + +E++ LT +L + A +Q+L
Sbjct: 1648 LRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL 1694
>AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein
protein.
Length = 2121
Score = 70.1 bits (164), Expect = 2e-11
Identities = 88/438 (20%), Positives = 182/438 (41%), Gaps = 28/438 (6%)
Query: 204 QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINT 263
Q ++ L R + K L+ + + ++ S S+ E + + + T V + +
Sbjct: 452 QEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTS 511
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI------EIEQLNARVVEAET 317
EL ++ + Q EL +Q + + +Q ++EQL++ + + E
Sbjct: 512 ELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ 571
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+LK + + Q +L + + + + +K+ E + +Q+QLQ
Sbjct: 572 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQ 631
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
V + AQ + E E+ E+ + Q+ E+Q +V EL + L S
Sbjct: 632 VANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL---ELQLRS 688
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQ----RVQTELKHTVEHLHEEQERIVKIEA 493
+ K E VA + D++ ++L+ E + ++ E + + L E+Q I +++A
Sbjct: 689 EQQK-ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKA 747
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILR 553
+SL + K LEE A G K + ++L+ + + E + +R AE +
Sbjct: 748 ETRSLVEQHKRERKELEEERA----GRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQH 803
Query: 554 KKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR 613
E +CE+ K ++ ++ E + Q+ + Y EQ ++ + R +
Sbjct: 804 TAES-------ECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKAR---Q 853
Query: 614 ELEAAEDRADVAESNLSL 631
EL+ A+++ ES+ L
Sbjct: 854 ELQEAKEKVAGIESHSEL 871
Score = 62.1 bits (144), Expect = 6e-09
Identities = 71/363 (19%), Positives = 154/363 (42%), Gaps = 13/363 (3%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
+ L + ++ +K+ + D ++Q + E+ A + E + LK ++ ++K+ +
Sbjct: 564 SSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK-QLEALEKEKAAK 622
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ L+ L VAN+ Q ++ + + E+ +E+Q ++ + AQ ++ L
Sbjct: 623 LEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL 682
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++ + + RV + +Q E+ Q L V +L K + L
Sbjct: 683 ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCI 742
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNISVRLEEV 512
E+ E R E+++R + EL+ EE+ +EA + L E V E+
Sbjct: 743 SELKAETRSLVEQHKRERKELE-------EERAGRKGLEARLQQLGEAHQAETEVLRREL 795
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
A A+ S+ E +K++ + + E + + QL + +CE+ ++
Sbjct: 796 -AEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQE 854
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
LQ++ EK + S + Q++ Q+ + + R ++++ E RA +LS +
Sbjct: 855 ---LQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTL 911
Query: 633 RAK 635
+ K
Sbjct: 912 QEK 914
Score = 48.4 bits (110), Expect = 8e-05
Identities = 88/422 (20%), Positives = 176/422 (41%), Gaps = 45/422 (10%)
Query: 273 LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQI 332
L Q +LK T K D + L++ + S ++ + + + + + L +E+T K
Sbjct: 302 LKQCQDLK-TEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDAL-NELTEEHSKATQ 359
Query: 333 QITELELSLDVANKTNIDLQKTI--KKQSLQ--LTEIQTHYDEVQRQ------------L 376
+ E + L+ + +K + K + LQ L++++ H ++Q L
Sbjct: 360 EWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVL 419
Query: 377 QV-TLDQYGVA----QRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRVNELTV 430
Q+ TL Q ++Q+ +E RG E L +R E++ ++ + + +L
Sbjct: 420 QLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQS 479
Query: 431 INVNLSSSKAKIEQEL----AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQE 486
NLS +K ++EQ A + A +T EL + Q+ EL + E+Q
Sbjct: 480 SISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQA 539
Query: 487 RIVKI----EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++ + E + L +V+ +S L++ E K + K EA +D +L
Sbjct: 540 QLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQL----KEVAEKQEATRQDHAQQLATAA 595
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ LR+++ LK++ +E + +LQ L+ ++ + + + +
Sbjct: 596 EEREAS---LRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKA 652
Query: 603 QSVTRVRRFQRELEAA-----EDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESR 657
+ +V Q +E A E +A VAE L L R++ + V + L ++ +
Sbjct: 653 ELSRKVEELQACVETARQEQHEAQAQVAELELQL-RSEQQKATEKERVAQEKDQLQEQLQ 711
Query: 658 AL 659
AL
Sbjct: 712 AL 713
Score = 46.4 bits (105), Expect = 3e-04
Identities = 67/334 (20%), Positives = 143/334 (42%), Gaps = 27/334 (8%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDL--QKTIKKQSLQ 361
E+ L +V E E + ++ K Q++ L+ + + + N L + + +Q L+
Sbjct: 1414 ELIPLRQKVAEQE-RTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLE 1472
Query: 362 LTEIQTHYDEVQRQLQVTLD---QYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQ 417
+ Q VQ V D + QR QS E+E + YE A ++V ++
Sbjct: 1473 VELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1532
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHT 477
EE Q ++ + V + K +EL+ AD D+ +K + ++ + VQ + +
Sbjct: 1533 QEERQKLTAQVEQLEV-FQREQTKQVEELSKKLADSDQASK---VQQQKLKAVQAQGGES 1588
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE 537
+ Q ++ +++A E ++ +++E+ + + +A+ K E
Sbjct: 1589 QQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH-----------YDAK-KQQNQE 1636
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
L E+ R +++ L+K+ ++L+ + + + L E+T + ++ R L Q
Sbjct: 1637 LQEQLR----SLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQ 1692
Query: 598 EGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
+ Q + + +FQ +A + R A+ L L
Sbjct: 1693 VAHADQQLRDLGKFQVATDALKSREPQAKPQLDL 1726
Score = 42.7 bits (96), Expect = 0.004
Identities = 84/500 (16%), Positives = 195/500 (39%), Gaps = 24/500 (4%)
Query: 168 QKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVN-RDYTNLSKNVLAKAL 226
++ A G + + L+E S+ Q ER + A T R +L+ A+A
Sbjct: 977 EREAEQMGNELERLRAALME-SQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAE 1035
Query: 227 MESKAMNSCDSRVTESIT-ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQ 285
+E + N+ + + E T + + + +L ++ + + +L EL++TVKQ
Sbjct: 1036 LEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQ 1095
Query: 286 FDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIK-KKLQIQITELELSLDVA 344
+ + E E + ++E ++E T K + L+ ++++LE
Sbjct: 1096 LKE----------QLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQ 1145
Query: 345 NKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY 404
+ L+++++ + E + + +Q QL+ + G +Q + S E+ R
Sbjct: 1146 QEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKV 1205
Query: 405 EQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + + + Q + + +L + + +++ + E+ + +
Sbjct: 1206 QDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAES 1265
Query: 465 ERYQRVQTELK----HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGG 520
E+ Q+++ L+ T + ER + +SL E + V E +
Sbjct: 1266 EKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQA 1325
Query: 521 KRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL 580
+R +L +K + E +K + T+++ + L ++ + + + Q +
Sbjct: 1326 ER-AEELGQELKAWQ-EKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAA 1383
Query: 581 EKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFV 640
EK ++ +Q A G + + R +R EL + E +RA+ ++
Sbjct: 1384 EKRHREELEQSKQAA---GGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYA 1440
Query: 641 -TTSTVPGSQVYLVQESRAL 659
S + + L +E+R L
Sbjct: 1441 EQLSMLKKAHGLLAEENRGL 1460
Score = 41.9 bits (94), Expect = 0.007
Identities = 41/167 (24%), Positives = 80/167 (47%), Gaps = 17/167 (10%)
Query: 280 KETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELEL 339
+E KQ ++LS L DS + + ++ ++L A V+A+ E + ++LQ Q+ EL+
Sbjct: 1551 REQTKQVEELSKK-LADSDQASKVQQQKLKA--VQAQG---GESQQEAQRLQAQLNELQA 1604
Query: 340 SLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEE 399
L ++ + LQ+ + +THYD ++Q Q +Q R ++ L E +E
Sbjct: 1605 QLS-------QKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQL----RSLEQLQKENKE 1653
Query: 400 IRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
+R E+ + + +E++ LT +L + A +Q+L
Sbjct: 1654 LRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL 1700
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 69.7 bits (163), Expect = 3e-11
Identities = 84/352 (23%), Positives = 166/352 (47%), Gaps = 38/352 (10%)
Query: 275 QLNELKETV----KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL 330
Q+N LKE + K+FD L + +D SK +E ++ N ET+LKS+ RI + L
Sbjct: 1480 QINLLKEELDQQNKRFDCLKGEMEDDKSK---MEKKESNL-----ETELKSQTARIME-L 1530
Query: 331 QIQITELELSLDVANKT--NIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVA 386
+ IT+ + ++ N+ N + QK I+ + L +L Q +E +++ ++
Sbjct: 1531 EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1590
Query: 387 QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
+ ++ S+ E+E + E +S E++ + + R+ + L+ K K EQ++
Sbjct: 1591 ENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA--AKLAELKRKAEQKI 1648
Query: 447 AIVA----ADYDEITKELRIADERY-QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI- 500
A + + +E ++ + E + + T+L+ +H +E++ +E+ + I
Sbjct: 1649 AAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIV 1708
Query: 501 --EVKNISVRLEEVEANAIVGGKRI----ISKLEARIKDMELELDEEKRRHAETIKILRK 554
KN++ E+ EA++ ++ IS L+ + + E L + ET+ +
Sbjct: 1709 PRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE 1768
Query: 555 KERQLKEVIIQCE-------EDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
Q +E +I+ E EDQ I LQ+ LE+ ++K S+ Q E+EG
Sbjct: 1769 MRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEG 1820
Score = 67.7 bits (158), Expect = 1e-10
Identities = 105/536 (19%), Positives = 226/536 (42%), Gaps = 51/536 (9%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ--TLLEESRRNVQ--NERMYKPD 202
++ E+++ +K+ L S++ +K Y+ + +++ T L+E R V E++ +
Sbjct: 1642 RKAEQKIAAIKKQ--LLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVE 1699
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
S TL+ +KNV A E C + E ++ T + R+
Sbjct: 1700 SSQSETLI---VPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVG 1756
Query: 263 TELPAIDNSYLNQLNELKETV--------KQFDDLSVY-ILNDSSKQTSIEIEQLNARVV 313
E +S+ + +E + KQ +D S+ L + ++ + + + A+ V
Sbjct: 1757 QEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHV 1816
Query: 314 EAE-----TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS----LQLTE 364
E E + K + + +Q + E EL+ + + +L + +Q +++ E
Sbjct: 1817 EKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEE 1876
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE----- 419
+ + Y+++Q L Q + + L EE ++ ++ ++E Q+
Sbjct: 1877 LTSKYEKLQ-----ALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFK 1931
Query: 420 ------ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
E Q E+ + +L + + +QEL I+ +YD+ +E +I E+ E
Sbjct: 1932 LAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQ-EREEKIKQEQED---LE 1987
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
LKH +E ++ ++ LE+ +K + +EVEA + + ++L +I +
Sbjct: 1988 LKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 2047
Query: 534 MELELDEEKRRHAETIKILRKK-ERQLKEVIIQCEEDQKNI-SLLQDSLEKTSQKVSI-- 589
+ +L +R+ E + ++ +++++ Q EE QK L+ + V+I
Sbjct: 2048 KDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIME 2107
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTV 645
+ QLA++ + S + + F+ ++ EDR E N+ H T V T+
Sbjct: 2108 LQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGHLTKVAICTI 2163
Score = 62.5 bits (145), Expect = 5e-09
Identities = 84/345 (24%), Positives = 153/345 (44%), Gaps = 23/345 (6%)
Query: 273 LNQLNEL-KETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKK 329
+NQL L KE K + ++ N + K++ E++Q +A++ + +S K
Sbjct: 758 INQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQSYQSATHEQTKA 816
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQ----LTEIQTHYDEVQRQLQVTLDQYGV 385
+ Q+ +L+ L I L K + + Q TE+ H +VQ +Q Q
Sbjct: 817 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 876
Query: 386 AQRRIQSLTGEVEEIR---GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+++++SLT +V E + GN EQ + VE++ Q R + I + AK
Sbjct: 877 MEQKVKSLT-QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAK- 934
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
E + I+ +Y+ K E+ ++ E++ T++ +QE +K E +LE+
Sbjct: 935 EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 994
Query: 503 KNISVR---LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA-ETIKILRKKERQ 558
K LE +AN+ G +S+LE K+ L E RR + I I KK Q
Sbjct: 995 KEKQFNAKMLEMAQANS-AGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQ 1053
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
E + + E Q + + + + QK+ ++ E+E M+++
Sbjct: 1054 QAEELQEIHEIQ--LQEKEQEVAELKQKILLFG---CEKEEMNKE 1093
Score = 61.7 bits (143), Expect = 8e-09
Identities = 82/453 (18%), Positives = 196/453 (43%), Gaps = 26/453 (5%)
Query: 149 IEKELDLYEKEVN--LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
+++EL ++EV + ++ A + K +A+ E +++ ER ++ + +
Sbjct: 455 LQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVA 514
Query: 207 RTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETV-RVRETSPTTCVVRINTEL 265
+Y +S+ K ES A+ + + +TE+ ++R+ R T +
Sbjct: 515 LEKSQSEYLKISQE---KEQQESLALEELELQKKAILTESENKLRDLQQEAETYR--TRI 569
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
+++S L E K K DL+V++ + +K + E E+ +
Sbjct: 570 LELESSLEKSLQENKNQSK---DLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDAL 626
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
+KLQ+ + + ++ + ++T+ K + Q H +E+ + TL++ V
Sbjct: 627 WTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII--FQAHIEEMNEK---TLEKLDV 681
Query: 386 AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQ 444
Q ++SL+ E+ E+ L+ + +E++ + + +++ + + K +Q
Sbjct: 682 KQTELESLSSELSEV-------LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ 734
Query: 445 ELAIVAADYD-EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
++ + +++ I + + ++ +++ LK +HL E Q + +EA K E E++
Sbjct: 735 QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQ 794
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
S +L+ ++ ++ + E + + LD E R T K + + E Q K+V
Sbjct: 795 QASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLT-KQVAEVEAQKKDVC 853
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
+ + + + L LEK + ++ + L +
Sbjct: 854 TELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 886
Score = 56.4 bits (130), Expect = 3e-07
Identities = 97/548 (17%), Positives = 232/548 (42%), Gaps = 57/548 (10%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+R+QE+EK DL+ E L ++LR + + + + E R+ + M + +
Sbjct: 325 ERLQELEKIKDLHMAEKTKLITQLRDAKNLIE-QLEQDKGMVIAETKRQMHETLEMKEEE 383
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
R+ + + T + K E A + ++ T + E + ++
Sbjct: 384 IAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALS-----TAQKTEEARRKLKAEMD 438
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
++ I+ + + L++ + + V ++ SS++ ++++L+ E +L +
Sbjct: 439 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLH------EKELARK 492
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ KKLQ + E + + VA + + I ++ Q + E+Q++ +T
Sbjct: 493 EQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILT--- 549
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
++ +++ L E E R + L ++ S+E+ +E++ + +L V +L + K K
Sbjct: 550 --ESENKLRDLQQEAETYR---TRILELESSLEKSLQENKNQSKDLAV---HLEAEKNKH 601
Query: 443 EQELAIVAADYDEITKELRIADERY---------QRVQTELKHTVEHLHEEQERIVKIEA 493
+E+ ++ + + L+ + Q+ QTE++ E +E+E ++K +
Sbjct: 602 NKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKE 661
Query: 494 V----------KKSLE-IEVKNISVRLEEVEANAIVGGKRIISKLEARIKD--------M 534
+ +K+LE ++VK + E + ++ + + + + +KD +
Sbjct: 662 IIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL 721
Query: 535 ELELDEEKRRHAETI-KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK----VSI 589
E ++DE+K H + + I+++ E ++ ++ + LL +K ++ V
Sbjct: 722 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVEN 781
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQ 649
+ + EG QQ+ ++ FQ A ++ E L+ ++ K T + Q
Sbjct: 782 LEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQ 841
Query: 650 VYLVQESR 657
V V+ +
Sbjct: 842 VAEVEAQK 849
Score = 52.0 bits (119), Expect = 7e-06
Identities = 92/481 (19%), Positives = 200/481 (41%), Gaps = 32/481 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+ + ++IE +++ +E+N + +K + + + I + L+E + V +
Sbjct: 1022 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKIL 1081
Query: 202 DFQASRTLVNRDYTNLSKNVLAK--ALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
F + +N++ T L + + + L E + S S+ + + V
Sbjct: 1082 LFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEV 1141
Query: 260 RINTELPAIDNSYL-NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+N L +N++L QL ELK ++ D V L K T E + L + ++
Sbjct: 1142 DLNKSLK--ENTFLQEQLVELKMLAEE-DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKS 1198
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L+ + KK + EL + LD+ K L + + + ++ +T + + ++
Sbjct: 1199 LEDKSLEFKKLSE----ELAIQLDICCKKTEALLEAKTNELINISSSKT--NAILSRISH 1252
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS 438
+ + + T V E+ Q + ++ ++++ ++ E + S
Sbjct: 1253 CQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEK---ENQIKSM 1309
Query: 439 KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
KA IE + A E + + A E+ + T+LK + L E + ++ K
Sbjct: 1310 KADIESLVTEKEALQKEGGNQQQAASEKESCI-TQLK---KELSENINAVTLMKEELKEK 1365
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
++E+ ++S +L ++ N + +S+ EA I + + DEEK + ++ L K
Sbjct: 1366 KVEISSLSKQLTDL--NVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDT 1423
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
L ++ IS L + ++ S K S +K++ A+ Q+ + + Q EL++
Sbjct: 1424 L---------SKEKISAL-EQVDDWSNKFSEWKKK-AQSRFTQHQNTVKELQIQLELKSK 1472
Query: 619 E 619
E
Sbjct: 1473 E 1473
Score = 49.2 bits (112), Expect = 5e-05
Identities = 74/359 (20%), Positives = 156/359 (43%), Gaps = 28/359 (7%)
Query: 293 ILNDSSKQTSIEIEQLN------ARVVEAETKLKSEVTRIKKKLQIQITE----LELSLD 342
++N SS +T+ + +++ +V EA V+ ++ +L+ Q+TE L +S
Sbjct: 1235 LINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLR-QLTEEQNTLNISFQ 1293
Query: 343 VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRG 402
A + + IK + + T + +Q++ +Q A + +T +E+
Sbjct: 1294 QATHQLEEKENQIKSMKADIESLVTEKEALQKEGG---NQQQAASEKESCITQLKKELSE 1350
Query: 403 NYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI--VAADYDEITKEL 460
N +K ++++ E + +LT +NV L +S + E+E AI + YDE EL
Sbjct: 1351 NINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCEL 1410
Query: 461 --RIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
++ D + +V T K + L + + K KK + ++E++ +
Sbjct: 1411 LDQVQDLSF-KVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLEL 1469
Query: 519 GGKRIISKLEARIKDMELELDEEKRR----HAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K K + +I ++ ELD++ +R E K E++ + + + I
Sbjct: 1470 KSKEAYEK-DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIM 1528
Query: 575 LLQDSL-EKTSQKVS---IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
L+D + +KT + S + K +++ ++ V +++ FQ E ++R AE +
Sbjct: 1529 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1587
Score = 33.9 bits (74), Expect = 1.8
Identities = 41/245 (16%), Positives = 100/245 (40%), Gaps = 15/245 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q K + +E + + + E L R+K + GK + + L + + Q + K
Sbjct: 1914 QPKLLSNMEAQHN--DLEFKLAGAEREKQKL--GKEIVRLQKDLRMLRKEHQQELEILKK 1969
Query: 202 DFQASRT---LVNRDYTNLSKNVLAKALME--SKAMNSCDSRVTESITETVRVRETSPTT 256
++ R ++ L N K LM + + + + +I ET+ +
Sbjct: 1970 EYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAE 2029
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ E + + ++LK T K++++ IL+ ++ + ++ L ++ E +
Sbjct: 2030 LLESHQEETNQLLKKIAEKDDDLKRTAKRYEE----ILDAREEEMTAKVRDLQTQLEELQ 2085
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQR 374
K + ++ + + +T +EL +A KT + +K+Q Q+ ++ + ++
Sbjct: 2086 KKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2145
Query: 375 QLQVT 379
+ T
Sbjct: 2146 NVYAT 2150
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 69.7 bits (163), Expect = 3e-11
Identities = 84/352 (23%), Positives = 166/352 (47%), Gaps = 38/352 (10%)
Query: 275 QLNELKETV----KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL 330
Q+N LKE + K+FD L + +D SK +E ++ N ET+LKS+ RI + L
Sbjct: 1480 QINLLKEELDQQNKRFDCLKGEMEDDKSK---MEKKESNL-----ETELKSQTARIME-L 1530
Query: 331 QIQITELELSLDVANKT--NIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVA 386
+ IT+ + ++ N+ N + QK I+ + L +L Q +E +++ ++
Sbjct: 1531 EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1590
Query: 387 QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
+ ++ S+ E+E + E +S E++ + + R+ + L+ K K EQ++
Sbjct: 1591 ENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA--AKLAELKRKAEQKI 1648
Query: 447 AIVA----ADYDEITKELRIADERY-QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI- 500
A + + +E ++ + E + + T+L+ +H +E++ +E+ + I
Sbjct: 1649 AAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIV 1708
Query: 501 --EVKNISVRLEEVEANAIVGGKRI----ISKLEARIKDMELELDEEKRRHAETIKILRK 554
KN++ E+ EA++ ++ IS L+ + + E L + ET+ +
Sbjct: 1709 PRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE 1768
Query: 555 KERQLKEVIIQCE-------EDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
Q +E +I+ E EDQ I LQ+ LE+ ++K S+ Q E+EG
Sbjct: 1769 MRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEG 1820
Score = 63.3 bits (147), Expect = 3e-09
Identities = 101/520 (19%), Positives = 221/520 (42%), Gaps = 51/520 (9%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ--TLLEESRRNVQ--NERMYKPD 202
++ E+++ +K+ L S++ +K Y+ + +++ T L+E R V E++ +
Sbjct: 1642 RKAEQKIAAIKKQ--LLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVE 1699
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
S TL+ +KNV A E C + E ++ T + R+
Sbjct: 1700 SSQSETLI---VPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVG 1756
Query: 263 TELPAIDNSYLNQLNELKETV--------KQFDDLSVY-ILNDSSKQTSIEIEQLNARVV 313
E +S+ + +E + KQ +D S+ L + ++ + + + A+ V
Sbjct: 1757 QEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHV 1816
Query: 314 EAE-----TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS----LQLTE 364
E E + K + + +Q + E EL+ + + +L + +Q +++ E
Sbjct: 1817 EKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEE 1876
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE----- 419
+ + Y+++Q L Q + + L EE ++ ++ ++E Q+
Sbjct: 1877 LTSKYEKLQ-----ALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFK 1931
Query: 420 ------ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
E Q E+ + +L + + +QEL I+ +YD+ +E +I E+ E
Sbjct: 1932 LAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQ-EREEKIKQEQED---LE 1987
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
LKH +E ++ ++ LE+ +K + +EVEA + + ++L +I +
Sbjct: 1988 LKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 2047
Query: 534 MELELDEEKRRHAETIKILRKK-ERQLKEVIIQCEEDQKNI-SLLQDSLEKTSQKVSI-- 589
+ +L +R+ E + ++ +++++ Q EE QK L+ + V+I
Sbjct: 2048 KDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIME 2107
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+ QLA++ + S + + F+ ++ EDR E N+
Sbjct: 2108 LQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNV 2147
Score = 62.5 bits (145), Expect = 5e-09
Identities = 84/345 (24%), Positives = 153/345 (44%), Gaps = 23/345 (6%)
Query: 273 LNQLNEL-KETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKK 329
+NQL L KE K + ++ N + K++ E++Q +A++ + +S K
Sbjct: 758 INQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQSYQSATHEQTKA 816
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQ----LTEIQTHYDEVQRQLQVTLDQYGV 385
+ Q+ +L+ L I L K + + Q TE+ H +VQ +Q Q
Sbjct: 817 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 876
Query: 386 AQRRIQSLTGEVEEIR---GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+++++SLT +V E + GN EQ + VE++ Q R + I + AK
Sbjct: 877 MEQKVKSLT-QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAK- 934
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
E + I+ +Y+ K E+ ++ E++ T++ +QE +K E +LE+
Sbjct: 935 EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 994
Query: 503 KNISVR---LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA-ETIKILRKKERQ 558
K LE +AN+ G +S+LE K+ L E RR + I I KK Q
Sbjct: 995 KEKQFNAKMLEMAQANS-AGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQ 1053
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
E + + E Q + + + + QK+ ++ E+E M+++
Sbjct: 1054 QAEELQEIHEIQ--LQEKEQEVAELKQKILLFG---CEKEEMNKE 1093
Score = 61.7 bits (143), Expect = 8e-09
Identities = 82/453 (18%), Positives = 196/453 (43%), Gaps = 26/453 (5%)
Query: 149 IEKELDLYEKEVN--LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
+++EL ++EV + ++ A + K +A+ E +++ ER ++ + +
Sbjct: 455 LQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVA 514
Query: 207 RTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETV-RVRETSPTTCVVRINTEL 265
+Y +S+ K ES A+ + + +TE+ ++R+ R T +
Sbjct: 515 LEKSQSEYLKISQE---KEQQESLALEELELQKKAILTESENKLRDLQQEAETYR--TRI 569
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
+++S L E K K DL+V++ + +K + E E+ +
Sbjct: 570 LELESSLEKSLQENKNQSK---DLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDAL 626
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
+KLQ+ + + ++ + ++T+ K + Q H +E+ + TL++ V
Sbjct: 627 WTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII--FQAHIEEMNEK---TLEKLDV 681
Query: 386 AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQ 444
Q ++SL+ E+ E+ L+ + +E++ + + +++ + + K +Q
Sbjct: 682 KQTELESLSSELSEV-------LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ 734
Query: 445 ELAIVAADYD-EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
++ + +++ I + + ++ +++ LK +HL E Q + +EA K E E++
Sbjct: 735 QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQ 794
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
S +L+ ++ ++ + E + + LD E R T K + + E Q K+V
Sbjct: 795 QASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLT-KQVAEVEAQKKDVC 853
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
+ + + + L LEK + ++ + L +
Sbjct: 854 TELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 886
Score = 56.4 bits (130), Expect = 3e-07
Identities = 97/548 (17%), Positives = 232/548 (42%), Gaps = 57/548 (10%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+R+QE+EK DL+ E L ++LR + + + + E R+ + M + +
Sbjct: 325 ERLQELEKIKDLHMAEKTKLITQLRDAKNLIE-QLEQDKGMVIAETKRQMHETLEMKEEE 383
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
R+ + + T + K E A + ++ T + E + ++
Sbjct: 384 IAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALS-----TAQKTEEARRKLKAEMD 438
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
++ I+ + + L++ + + V ++ SS++ ++++L+ E +L +
Sbjct: 439 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLH------EKELARK 492
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ KKLQ + E + + VA + + I ++ Q + E+Q++ +T
Sbjct: 493 EQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILT--- 549
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
++ +++ L E E R + L ++ S+E+ +E++ + +L V +L + K K
Sbjct: 550 --ESENKLRDLQQEAETYR---TRILELESSLEKSLQENKNQSKDLAV---HLEAEKNKH 601
Query: 443 EQELAIVAADYDEITKELRIADERY---------QRVQTELKHTVEHLHEEQERIVKIEA 493
+E+ ++ + + L+ + Q+ QTE++ E +E+E ++K +
Sbjct: 602 NKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKE 661
Query: 494 V----------KKSLE-IEVKNISVRLEEVEANAIVGGKRIISKLEARIKD--------M 534
+ +K+LE ++VK + E + ++ + + + + +KD +
Sbjct: 662 IIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL 721
Query: 535 ELELDEEKRRHAETI-KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK----VSI 589
E ++DE+K H + + I+++ E ++ ++ + LL +K ++ V
Sbjct: 722 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVEN 781
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQ 649
+ + EG QQ+ ++ FQ A ++ E L+ ++ K T + Q
Sbjct: 782 LEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQ 841
Query: 650 VYLVQESR 657
V V+ +
Sbjct: 842 VAEVEAQK 849
Score = 52.0 bits (119), Expect = 7e-06
Identities = 92/481 (19%), Positives = 200/481 (41%), Gaps = 32/481 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+ + ++IE +++ +E+N + +K + + + I + L+E + V +
Sbjct: 1022 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKIL 1081
Query: 202 DFQASRTLVNRDYTNLSKNVLAK--ALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
F + +N++ T L + + + L E + S S+ + + V
Sbjct: 1082 LFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEV 1141
Query: 260 RINTELPAIDNSYL-NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+N L +N++L QL ELK ++ D V L K T E + L + ++
Sbjct: 1142 DLNKSLK--ENTFLQEQLVELKMLAEE-DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKS 1198
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L+ + KK + EL + LD+ K L + + + ++ +T + + ++
Sbjct: 1199 LEDKSLEFKKLSE----ELAIQLDICCKKTEALLEAKTNELINISSSKT--NAILSRISH 1252
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS 438
+ + + T V E+ Q + ++ ++++ ++ E + S
Sbjct: 1253 CQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEK---ENQIKSM 1309
Query: 439 KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
KA IE + A E + + A E+ + T+LK + L E + ++ K
Sbjct: 1310 KADIESLVTEKEALQKEGGNQQQAASEKESCI-TQLK---KELSENINAVTLMKEELKEK 1365
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
++E+ ++S +L ++ N + +S+ EA I + + DEEK + ++ L K
Sbjct: 1366 KVEISSLSKQLTDL--NVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDT 1423
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
L ++ IS L + ++ S K S +K++ A+ Q+ + + Q EL++
Sbjct: 1424 L---------SKEKISAL-EQVDDWSNKFSEWKKK-AQSRFTQHQNTVKELQIQLELKSK 1472
Query: 619 E 619
E
Sbjct: 1473 E 1473
Score = 49.2 bits (112), Expect = 5e-05
Identities = 74/359 (20%), Positives = 156/359 (43%), Gaps = 28/359 (7%)
Query: 293 ILNDSSKQTSIEIEQLN------ARVVEAETKLKSEVTRIKKKLQIQITE----LELSLD 342
++N SS +T+ + +++ +V EA V+ ++ +L+ Q+TE L +S
Sbjct: 1235 LINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLR-QLTEEQNTLNISFQ 1293
Query: 343 VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRG 402
A + + IK + + T + +Q++ +Q A + +T +E+
Sbjct: 1294 QATHQLEEKENQIKSMKADIESLVTEKEALQKEGG---NQQQAASEKESCITQLKKELSE 1350
Query: 403 NYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI--VAADYDEITKEL 460
N +K ++++ E + +LT +NV L +S + E+E AI + YDE EL
Sbjct: 1351 NINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCEL 1410
Query: 461 --RIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
++ D + +V T K + L + + K KK + ++E++ +
Sbjct: 1411 LDQVQDLSF-KVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLEL 1469
Query: 519 GGKRIISKLEARIKDMELELDEEKRR----HAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K K + +I ++ ELD++ +R E K E++ + + + I
Sbjct: 1470 KSKEAYEK-DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIM 1528
Query: 575 LLQDSL-EKTSQKVS---IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
L+D + +KT + S + K +++ ++ V +++ FQ E ++R AE +
Sbjct: 1529 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1587
Score = 33.9 bits (74), Expect = 1.8
Identities = 41/245 (16%), Positives = 100/245 (40%), Gaps = 15/245 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q K + +E + + + E L R+K + GK + + L + + Q + K
Sbjct: 1914 QPKLLSNMEAQHN--DLEFKLAGAEREKQKL--GKEIVRLQKDLRMLRKEHQQELEILKK 1969
Query: 202 DFQASRT---LVNRDYTNLSKNVLAKALME--SKAMNSCDSRVTESITETVRVRETSPTT 256
++ R ++ L N K LM + + + + +I ET+ +
Sbjct: 1970 EYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAE 2029
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ E + + ++LK T K++++ IL+ ++ + ++ L ++ E +
Sbjct: 2030 LLESHQEETNQLLKKIAEKDDDLKRTAKRYEE----ILDAREEEMTAKVRDLQTQLEELQ 2085
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQR 374
K + ++ + + +T +EL +A KT + +K+Q Q+ ++ + ++
Sbjct: 2086 KKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2145
Query: 375 QLQVT 379
+ T
Sbjct: 2146 NVYAT 2150
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 69.7 bits (163), Expect = 3e-11
Identities = 84/352 (23%), Positives = 166/352 (47%), Gaps = 38/352 (10%)
Query: 275 QLNELKETV----KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKL 330
Q+N LKE + K+FD L + +D SK +E ++ N ET+LKS+ RI + L
Sbjct: 1335 QINLLKEELDQQNKRFDCLKGEMEDDKSK---MEKKESNL-----ETELKSQTARIME-L 1385
Query: 331 QIQITELELSLDVANKT--NIDLQKTIKKQSL--QLTEIQTHYDEVQRQLQVTLDQYGVA 386
+ IT+ + ++ N+ N + QK I+ + L +L Q +E +++ ++
Sbjct: 1386 EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1445
Query: 387 QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
+ ++ S+ E+E + E +S E++ + + R+ + L+ K K EQ++
Sbjct: 1446 ENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA--AKLAELKRKAEQKI 1503
Query: 447 AIVA----ADYDEITKELRIADERY-QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI- 500
A + + +E ++ + E + + T+L+ +H +E++ +E+ + I
Sbjct: 1504 AAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIV 1563
Query: 501 --EVKNISVRLEEVEANAIVGGKRI----ISKLEARIKDMELELDEEKRRHAETIKILRK 554
KN++ E+ EA++ ++ IS L+ + + E L + ET+ +
Sbjct: 1564 PRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE 1623
Query: 555 KERQLKEVIIQCE-------EDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
Q +E +I+ E EDQ I LQ+ LE+ ++K S+ Q E+EG
Sbjct: 1624 MRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEG 1675
Score = 63.3 bits (147), Expect = 3e-09
Identities = 101/520 (19%), Positives = 221/520 (42%), Gaps = 51/520 (9%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ--TLLEESRRNVQ--NERMYKPD 202
++ E+++ +K+ L S++ +K Y+ + +++ T L+E R V E++ +
Sbjct: 1497 RKAEQKIAAIKKQ--LLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVE 1554
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
S TL+ +KNV A E C + E ++ T + R+
Sbjct: 1555 SSQSETLI---VPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVG 1611
Query: 263 TELPAIDNSYLNQLNELKETV--------KQFDDLSVY-ILNDSSKQTSIEIEQLNARVV 313
E +S+ + +E + KQ +D S+ L + ++ + + + A+ V
Sbjct: 1612 QEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHV 1671
Query: 314 EAE-----TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS----LQLTE 364
E E + K + + +Q + E EL+ + + +L + +Q +++ E
Sbjct: 1672 EKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEE 1731
Query: 365 IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYE----- 419
+ + Y+++Q L Q + + L EE ++ ++ ++E Q+
Sbjct: 1732 LTSKYEKLQ-----ALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFK 1786
Query: 420 ------ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
E Q E+ + +L + + +QEL I+ +YD+ +E +I E+ E
Sbjct: 1787 LAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQ-EREEKIKQEQED---LE 1842
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
LKH +E ++ ++ LE+ +K + +EVEA + + ++L +I +
Sbjct: 1843 LKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 1902
Query: 534 MELELDEEKRRHAETIKILRKK-ERQLKEVIIQCEEDQKNI-SLLQDSLEKTSQKVSI-- 589
+ +L +R+ E + ++ +++++ Q EE QK L+ + V+I
Sbjct: 1903 KDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIME 1962
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+ QLA++ + S + + F+ ++ EDR E N+
Sbjct: 1963 LQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNV 2002
Score = 62.5 bits (145), Expect = 5e-09
Identities = 84/345 (24%), Positives = 153/345 (44%), Gaps = 23/345 (6%)
Query: 273 LNQLNEL-KETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKK 329
+NQL L KE K + ++ N + K++ E++Q +A++ + +S K
Sbjct: 613 INQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQSYQSATHEQTKA 671
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQ----LTEIQTHYDEVQRQLQVTLDQYGV 385
+ Q+ +L+ L I L K + + Q TE+ H +VQ +Q Q
Sbjct: 672 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 731
Query: 386 AQRRIQSLTGEVEEIR---GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+++++SLT +V E + GN EQ + VE++ Q R + I + AK
Sbjct: 732 MEQKVKSLT-QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAK- 789
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
E + I+ +Y+ K E+ ++ E++ T++ +QE +K E +LE+
Sbjct: 790 EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 849
Query: 503 KNISVR---LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA-ETIKILRKKERQ 558
K LE +AN+ G +S+LE K+ L E RR + I I KK Q
Sbjct: 850 KEKQFNAKMLEMAQANS-AGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQ 908
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
E + + E Q + + + + QK+ ++ E+E M+++
Sbjct: 909 QAEELQEIHEIQ--LQEKEQEVAELKQKILLFG---CEKEEMNKE 948
Score = 58.4 bits (135), Expect = 8e-08
Identities = 80/453 (17%), Positives = 196/453 (43%), Gaps = 26/453 (5%)
Query: 149 IEKELDLYEKEVN--LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
+++EL ++EV + ++ A + K +A+ E +++ ER ++ + +
Sbjct: 310 LQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVA 369
Query: 207 RTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETV-RVRETSPTTCVVRINTEL 265
+Y +S+ K ES A+ + + +TE+ ++R+ R T +
Sbjct: 370 LEKSQSEYLKISQE---KEQQESLALEELELQKKAILTESENKLRDLQQEAETYR--TRI 424
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
+++S L +E Q DL+V++ + +K + E E+ +
Sbjct: 425 LELESSLEKSL---QENENQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDAL 481
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
++LQ+ + + ++ + ++T+ K + Q H +E+ + TL++ V
Sbjct: 482 WAEELQVLKQQYQTEMEKLREKCEQEKETLLKDKEII--FQAHIEEMNEK---TLEKLDV 536
Query: 386 AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQ 444
Q ++SL+ E+ E+ L+ + +E++ + + +++ + + K +Q
Sbjct: 537 NQTELESLSSELSEV-------LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ 589
Query: 445 ELAIVAADYD-EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
++ + +++ I + + ++ +++ LK +HL E Q + +EA K E E++
Sbjct: 590 QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQ 649
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
S +L+ ++ ++ + E + + LD E R T K + + E Q K+V
Sbjct: 650 QASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLT-KQVAEVEAQKKDVC 708
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
+ + + + L LEK + ++ + L +
Sbjct: 709 TELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 741
Score = 55.2 bits (127), Expect = 7e-07
Identities = 98/548 (17%), Positives = 233/548 (42%), Gaps = 57/548 (10%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+R+QE+EK DL+ E L ++LR + + + + E R+ + M + +
Sbjct: 180 ERLQELEKIKDLHMAEKTKLITQLRDAKNLIE-QLEQDKGMVIAETKRQMHETLEMKEEE 238
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
R+ + + T + K E A + ++ T + E + ++
Sbjct: 239 IAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALS-----TAQKTEEARRKLKAEMD 293
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
++ I+ + + L++ + + V ++ SS++ ++++L+ E +L +
Sbjct: 294 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLH------EKELARK 347
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ KKLQ + E + + VA + + I ++ Q + E+Q++ +T
Sbjct: 348 EQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILT--- 404
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
++ +++ L E E R + L ++ S+E+ +E++ + +L V +L + K K
Sbjct: 405 --ESENKLRDLQQEAETYR---TRILELESSLEKSLQENENQSKDLAV---HLEAEKNKH 456
Query: 443 EQELAIVAADYDEITKELRIADERY---------QRVQTELKHTVEHLHEEQERIVKIEA 493
+E+ ++ + + L+ + Q+ QTE++ E +E+E ++K +
Sbjct: 457 NKEITVMVEKHKTELESLKHQQDALWAEELQVLKQQYQTEMEKLREKCEQEKETLLKDKE 516
Query: 494 V----------KKSLE------IEVKNISVRLEEV--EANAIVGGKRIISKLEARIK-DM 534
+ +K+LE E++++S L EV + + ++ ++K ++
Sbjct: 517 IIFQAHIEEMNEKTLEKLDVNQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL 576
Query: 535 ELELDEEKRRHAETI-KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK----VSI 589
E ++DE+K H + + I+++ E ++ ++ + LL +K ++ V
Sbjct: 577 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVEN 636
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQ 649
+ + EG QQ+ ++ FQ A ++ E L+ ++ K T + Q
Sbjct: 637 LEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQ 696
Query: 650 VYLVQESR 657
V V+ +
Sbjct: 697 VAEVEAQK 704
Score = 52.0 bits (119), Expect = 7e-06
Identities = 92/481 (19%), Positives = 200/481 (41%), Gaps = 32/481 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+ + ++IE +++ +E+N + +K + + + I + L+E + V +
Sbjct: 877 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKIL 936
Query: 202 DFQASRTLVNRDYTNLSKNVLAK--ALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
F + +N++ T L + + + L E + S S+ + + V
Sbjct: 937 LFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEV 996
Query: 260 RINTELPAIDNSYL-NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+N L +N++L QL ELK ++ D V L K T E + L + ++
Sbjct: 997 DLNKSLK--ENTFLQEQLVELKMLAEE-DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKS 1053
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L+ + KK + EL + LD+ K L + + + ++ +T + + ++
Sbjct: 1054 LEDKSLEFKKLSE----ELAIQLDICCKKTEALLEAKTNELINISSSKT--NAILSRISH 1107
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS 438
+ + + T V E+ Q + ++ ++++ ++ E + S
Sbjct: 1108 CQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEK---ENQIKSM 1164
Query: 439 KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
KA IE + A E + + A E+ + T+LK + L E + ++ K
Sbjct: 1165 KADIESLVTEKEALQKEGGNQQQAASEKESCI-TQLK---KELSENINAVTLMKEELKEK 1220
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
++E+ ++S +L ++ N + +S+ EA I + + DEEK + ++ L K
Sbjct: 1221 KVEISSLSKQLTDL--NVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDT 1278
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
L ++ IS L + ++ S K S +K++ A+ Q+ + + Q EL++
Sbjct: 1279 L---------SKEKISAL-EQVDDWSNKFSEWKKK-AQSRFTQHQNTVKELQIQLELKSK 1327
Query: 619 E 619
E
Sbjct: 1328 E 1328
Score = 49.2 bits (112), Expect = 5e-05
Identities = 74/359 (20%), Positives = 156/359 (43%), Gaps = 28/359 (7%)
Query: 293 ILNDSSKQTSIEIEQLN------ARVVEAETKLKSEVTRIKKKLQIQITE----LELSLD 342
++N SS +T+ + +++ +V EA V+ ++ +L+ Q+TE L +S
Sbjct: 1090 LINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLR-QLTEEQNTLNISFQ 1148
Query: 343 VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRG 402
A + + IK + + T + +Q++ +Q A + +T +E+
Sbjct: 1149 QATHQLEEKENQIKSMKADIESLVTEKEALQKEGG---NQQQAASEKESCITQLKKELSE 1205
Query: 403 NYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI--VAADYDEITKEL 460
N +K ++++ E + +LT +NV L +S + E+E AI + YDE EL
Sbjct: 1206 NINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCEL 1265
Query: 461 --RIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
++ D + +V T K + L + + K KK + ++E++ +
Sbjct: 1266 LDQVQDLSF-KVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLEL 1324
Query: 519 GGKRIISKLEARIKDMELELDEEKRR----HAETIKILRKKERQLKEVIIQCEEDQKNIS 574
K K + +I ++ ELD++ +R E K E++ + + + I
Sbjct: 1325 KSKEAYEK-DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIM 1383
Query: 575 LLQDSL-EKTSQKVS---IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
L+D + +KT + S + K +++ ++ V +++ FQ E ++R AE +
Sbjct: 1384 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1442
Score = 33.9 bits (74), Expect = 1.8
Identities = 41/245 (16%), Positives = 100/245 (40%), Gaps = 15/245 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q K + +E + + + E L R+K + GK + + L + + Q + K
Sbjct: 1769 QPKLLSNMEAQHN--DLEFKLAGAEREKQKL--GKEIVRLQKDLRMLRKEHQQELEILKK 1824
Query: 202 DFQASRT---LVNRDYTNLSKNVLAKALME--SKAMNSCDSRVTESITETVRVRETSPTT 256
++ R ++ L N K LM + + + + +I ET+ +
Sbjct: 1825 EYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAE 1884
Query: 257 CVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAE 316
+ E + + ++LK T K++++ IL+ ++ + ++ L ++ E +
Sbjct: 1885 LLESHQEETNQLLKKIAEKDDDLKRTAKRYEE----ILDAREEEMTAKVRDLQTQLEELQ 1940
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSL--QLTEIQTHYDEVQR 374
K + ++ + + +T +EL +A KT + +K+Q Q+ ++ + ++
Sbjct: 1941 KKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2000
Query: 375 QLQVT 379
+ T
Sbjct: 2001 NVYAT 2005
>AL590431-12|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein.
Length = 242
Score = 69.7 bits (163), Expect = 3e-11
Identities = 54/227 (23%), Positives = 115/227 (50%), Gaps = 12/227 (5%)
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
IKKK+Q+ + E +LD A + + QK +++S QL + +Q++L+ T D+
Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEAE-QKQAEERSKQLED---ELAAMQKKLKGTEDELDR 59
Query: 386 AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY--EESQTRVNELTVINVNLSSSKA--- 440
AQ R+ + ++EE +++ R + +E + +E + + E+ + + +A
Sbjct: 60 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 119
Query: 441 --KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
++ ++L I+ D + + +A+ + ++ ELK+ +L + + K +
Sbjct: 120 YEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKY 179
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
E E+K ++ +L+E E A +R ++KLE I D+E EL +K ++
Sbjct: 180 EEEIKILTDKLKEAETRAEF-AERSVAKLEKTIDDLEDELYAQKLKY 225
Score = 42.3 bits (95), Expect = 0.005
Identities = 36/156 (23%), Positives = 78/156 (50%), Gaps = 23/156 (14%)
Query: 491 IEAVKKS---LEIEVKNISVRLEEVEANAIVGGKRI------ISKLEARIKDMELELDEE 541
+EA+KK L+++ +N R E+ EA +R ++ ++ ++K E ELD
Sbjct: 1 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDRA 60
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
+ R A ++ L + E+ +E ++ + ++++ K +K+ + + QL E + ++
Sbjct: 61 QERLATALQKLEEAEKA-------ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIA 113
Query: 602 QQSVTRVRRFQR-------ELEAAEDRADVAESNLS 630
+++ + R +LE E+RA++AES S
Sbjct: 114 EEADRKYEEVARKLVIIEGDLERTEERAELAESKCS 149
>AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens
cDNA FLJ35371 fis, clone SKMUS2001740, highly similar to
TROPOMYOSIN ALPHA CHAIN, SKELETAL MUSCLE TYPE. ).
Length = 243
Score = 69.7 bits (163), Expect = 3e-11
Identities = 54/227 (23%), Positives = 115/227 (50%), Gaps = 12/227 (5%)
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
IKKK+Q+ + E +LD A + + QK +++S QL + +Q++L+ T D+
Sbjct: 5 IKKKMQMLKLDKENALDRAEQAEAE-QKQAEERSKQLED---ELAAMQKKLKGTEDELDR 60
Query: 386 AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY--EESQTRVNELTVINVNLSSSKA--- 440
AQ R+ + ++EE +++ R + +E + +E + + E+ + + +A
Sbjct: 61 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 120
Query: 441 --KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
++ ++L I+ D + + +A+ + ++ ELK+ +L + + K +
Sbjct: 121 YEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKY 180
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
E E+K ++ +L+E E A +R ++KLE I D+E EL +K ++
Sbjct: 181 EEEIKILTDKLKEAETRAEF-AERSVAKLEKTIDDLEDELYAQKLKY 226
Score = 42.3 bits (95), Expect = 0.005
Identities = 36/156 (23%), Positives = 78/156 (50%), Gaps = 23/156 (14%)
Query: 491 IEAVKKS---LEIEVKNISVRLEEVEANAIVGGKRI------ISKLEARIKDMELELDEE 541
+EA+KK L+++ +N R E+ EA +R ++ ++ ++K E ELD
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDRA 61
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
+ R A ++ L + E+ +E ++ + ++++ K +K+ + + QL E + ++
Sbjct: 62 QERLATALQKLEEAEKA-------ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIA 114
Query: 602 QQSVTRVRRFQR-------ELEAAEDRADVAESNLS 630
+++ + R +LE E+RA++AES S
Sbjct: 115 EEADRKYEEVARKLVIIEGDLERTEERAELAESKCS 150
>BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 69.3 bits (162), Expect = 4e-11
Identities = 80/370 (21%), Positives = 166/370 (44%), Gaps = 26/370 (7%)
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLNARVVEAETKL 319
N L A + Y EL++ + +F + + L + ++ EI+ L A +A KL
Sbjct: 261 NFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKAN-KL 319
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTN-------IDLQKTIKKQSLQLTEIQTHYDEV 372
+S V ++KLQ + +L + +TN + L++ +KK + T+++T+ +V
Sbjct: 320 ESTVEIYRQKLQ-DLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQV 378
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
Q L V L +R +L E++ + +E L+ K + +Q + + EL
Sbjct: 379 Q-DLHVKLSS---ESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQ 434
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
V + + Q A Y+ + E+ + R ++ + ++ + L +E +IE
Sbjct: 435 V----QQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIE 490
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE--KRRHAETIK 550
+++ LE + + ++ E+E + +R I +L+ +I+D++ L E+ K + K
Sbjct: 491 ELQEQLEQKHR----KMNELETEQRLSKER-IRELQQQIEDLQKSLQEQGSKSEGESSSK 545
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
+ +K E ++++ EE QK L++D +Q V A + + R
Sbjct: 546 LKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEER 605
Query: 611 FQRELEAAED 620
++ LE A +
Sbjct: 606 YKMYLEKARN 615
>AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 69.3 bits (162), Expect = 4e-11
Identities = 80/370 (21%), Positives = 166/370 (44%), Gaps = 26/370 (7%)
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLNARVVEAETKL 319
N L A + Y EL++ + +F + + L + ++ EI+ L A +A KL
Sbjct: 261 NFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKAN-KL 319
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTN-------IDLQKTIKKQSLQLTEIQTHYDEV 372
+S V ++KLQ + +L + +TN + L++ +KK + T+++T+ +V
Sbjct: 320 ESTVEIYRQKLQ-DLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQV 378
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
Q L V L +R +L E++ + +E L+ K + +Q + + EL
Sbjct: 379 Q-DLHVKLSS---ESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQ 434
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
V + + Q A Y+ + E+ + R ++ + ++ + L +E +IE
Sbjct: 435 V----QQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIE 490
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE--KRRHAETIK 550
+++ LE + + ++ E+E + +R I +L+ +I+D++ L E+ K + K
Sbjct: 491 ELQEQLEQKHR----KMNELETEQRLSKER-IRELQQQIEDLQKSLQEQGSKSEGESSSK 545
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
+ +K E ++++ EE QK L++D +Q V A + + R
Sbjct: 546 LKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEER 605
Query: 611 FQRELEAAED 620
++ LE A +
Sbjct: 606 YKMYLEKARN 615
>AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein.
Length = 728
Score = 69.3 bits (162), Expect = 4e-11
Identities = 80/370 (21%), Positives = 166/370 (44%), Gaps = 26/370 (7%)
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLNARVVEAETKL 319
N L A + Y EL++ + +F + + L + ++ EI+ L A +A KL
Sbjct: 261 NFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKAN-KL 319
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTN-------IDLQKTIKKQSLQLTEIQTHYDEV 372
+S V ++KLQ + +L + +TN + L++ +KK + T+++T+ +V
Sbjct: 320 ESTVEIYRQKLQ-DLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQV 378
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
Q L V L +R +L E++ + +E L+ K + +Q + + EL
Sbjct: 379 Q-DLHVKLSS---ESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQ 434
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
V + + Q A Y+ + E+ + R ++ + ++ + L +E +IE
Sbjct: 435 V----QQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIE 490
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE--KRRHAETIK 550
+++ LE + + ++ E+E + +R I +L+ +I+D++ L E+ K + K
Sbjct: 491 ELQEQLEQKHR----KMNELETEQRLSKER-IRELQQQIEDLQKSLQEQGSKSEGESSSK 545
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
+ +K E ++++ EE QK L++D +Q V A + + R
Sbjct: 546 LKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEER 605
Query: 611 FQRELEAAED 620
++ LE A +
Sbjct: 606 YKMYLEKARN 615
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 68.9 bits (161), Expect = 5e-11
Identities = 101/495 (20%), Positives = 211/495 (42%), Gaps = 46/495 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+K R+ E+EK+L L +EV +ELR++ + ++ +LL+E + + +
Sbjct: 248 EKSRIMELEKDLALRVQEV---AELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRT 304
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
D Q T + +++ + K + S+ ES+ + + +
Sbjct: 305 DHQREITSL-KEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALW 363
Query: 262 NTELPAIDNSYLNQLNELKET--------VKQFDDLSVYI----LNDSSKQTSIEIEQLN 309
++L S+ + ELK + +F +L I L+ + +++ +Q +
Sbjct: 364 KSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDS 423
Query: 310 ARVVEAE--TKLKSEVTRIKKKLQIQITELELSLDVANKTN-IDLQKTIKK------QSL 360
R A+ L++++ ++ K+ + + + LD A + ++++ T+ K +
Sbjct: 424 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKKE 483
Query: 361 QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGN---YEQALRVKRSVEQQ 417
+ E VQR +Q T+++ + + L+ ++E++R N E R K E+Q
Sbjct: 484 KFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQ 543
Query: 418 Y----EESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
E+ + + E+ ++ + SS K+ EL + D +E+ +L A+E +Q
Sbjct: 544 LIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKS 603
Query: 474 LKH-TVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
++ TV+ +QE K E KK LE ++ ++ ++E +L+AR
Sbjct: 604 IEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQC--------QELKAR-- 653
Query: 533 DMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKR 592
E E K +H E ++ L+K ++ + E+ N LLQ+ E Q
Sbjct: 654 -YERATSETKTKHEEILQNLQKTLLDTEDKLKGAREE--NSGLLQELEELRKQAEKAKAA 710
Query: 593 QLAEQEGMSQQSVTR 607
Q AE + +T+
Sbjct: 711 QTAEDAMQIMEQMTK 725
Score = 62.1 bits (144), Expect = 6e-09
Identities = 98/510 (19%), Positives = 206/510 (40%), Gaps = 51/510 (10%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITE 245
+E+ + V+ E + K D + L + L +++L + K + +++E
Sbjct: 189 VEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSE 248
Query: 246 TVRVRETSPTTCVV---------RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILND 296
R+ E + R+ + PA D L+ L+E + L V +
Sbjct: 249 KSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDM--SLSLLQEISSLQEKLEVTRTDH 306
Query: 297 SSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK 356
+ TS++ E AR + ++K+ T +K L + L+ L+ ANK N D+ +
Sbjct: 307 QREITSLK-EHFGAREETHQKEIKALYTATEK-LSKENESLKSKLEHANKENSDVI-ALW 363
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQ-YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
K L+ T I +H + +L+V+ + G L ++E++R +Y+ ++
Sbjct: 364 KSKLE-TAIASH-QQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQH--EIENLQN 419
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD--------------------E 455
QQ E E+ + L + E L + + D E
Sbjct: 420 QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAE 479
Query: 456 ITKE-LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
I KE A E VQ ++ TV LH+++E+ + + + L + ++ + E +
Sbjct: 480 IKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDE 539
Query: 515 NA--IVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
++ K KLE I ++ + + + LR KER ++E+ ++ + +N
Sbjct: 540 REEQLIKAKE---KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANEN 596
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
S LQ S+E + K + ++QE + + + +R+L E + + + + +
Sbjct: 597 ASFLQKSIEDMT-----VKAEQSQQEAAKKHEEEK-KELERKLSDLEKKMETSHNQCQEL 650
Query: 633 RAKHRTFVTTSTVPGSQVYLVQESRALSSE 662
+A++ + + ++ + L +E
Sbjct: 651 KARYERATSETKTKHEEILQNLQKTLLDTE 680
Score = 58.8 bits (136), Expect = 6e-08
Identities = 80/394 (20%), Positives = 178/394 (45%), Gaps = 49/394 (12%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
++++L+ V+ D V +LN ++ ++E L RV E E+ K ++ K +I
Sbjct: 160 KMDQLRTMVEAADREKVELLNQLEEEKR-KVEDLQFRV-EEESITKGDLETQTKLEHARI 217
Query: 335 TELELSLDVANKTNID-LQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
ELE SL + KT D LQ+ ++ + ++ E+++ L + + + +RR++S
Sbjct: 218 KELEQSL-LFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLES- 275
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
+ G+ + +L + + + E +L V + +++ +
Sbjct: 276 ----NKPAGDVDMSLSLLQEISSLQE-------KLEVTRTDHQREITSLKEHFGAREETH 324
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVE 513
+ K L A E+ + LK +EH ++E ++ + K LE + + +EE++
Sbjct: 325 QKEIKALYTATEKLSKENESLKSKLEHANKENSDVIAL--WKSKLETAIASHQQAMEELK 382
Query: 514 ANAIVG-GKRI--ISKLEARIKDMELEL-----------DEEKRRH--------AETIKI 551
+ G G ++L+ +I+ M L+ D E+ H A+ +K+
Sbjct: 383 VSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKV 442
Query: 552 LRKKERQLKEVIIQCEE-DQKNISLLQDSLEKTSQKVSIYKRQLAE--QEGMS-----QQ 603
+++KE L+ + + ++ + +++ ++D+L K Q+ I K + AE +E +S Q+
Sbjct: 443 IKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKL-QEAEIKKEKFAEASEEAVSVQRSMQE 501
Query: 604 SVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+V ++ + + + + NL+ + AK R
Sbjct: 502 TVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFR 535
Score = 56.8 bits (131), Expect = 2e-07
Identities = 86/398 (21%), Positives = 174/398 (43%), Gaps = 30/398 (7%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQL--NARVVEAET 317
++ T + A D + LN+L+E ++ +DL + +S + +E + +AR+ E E
Sbjct: 163 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQ 222
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNI-DLQKTIKKQSLQLTEIQTHYDEVQRQL 376
L E T+ KLQ ++ + ++ V+ K+ I +L+K + + ++ E++ + +
Sbjct: 223 SLLFEKTK-ADKLQRELEDTRVA-TVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG 280
Query: 377 QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL-RVKRSVEQQYEESQTRVNELTVINVNL 435
V D + I SL ++E R ++++ + +K + E Q + L L
Sbjct: 281 DV--DMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKL 338
Query: 436 SSSKAKIEQELAIVAADYDEI----TKELRIADERYQRVQTELKHTVE-----HLHEEQE 486
S ++ +L + ++ +L A +Q+ ELK + E E
Sbjct: 339 SKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAE 398
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME--LELDEEKRR 544
+IE ++ + E++N+ + + A + + +KL IK+ E LE K
Sbjct: 399 LKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLD 458
Query: 545 HAETIKILRKKE--RQLKEVIIQCE---EDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
AE ++ ++ +L+E I+ E E + +Q S+++T K+ Q EQ
Sbjct: 459 KAEDQHLVEMEDTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKL----HQKEEQFN 514
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
M + ++R ++EA D E LI+AK +
Sbjct: 515 MLSSDLEKLRENLADMEAKFREKDEREE--QLIKAKEK 550
Score = 54.8 bits (126), Expect = 9e-07
Identities = 79/405 (19%), Positives = 182/405 (44%), Gaps = 29/405 (7%)
Query: 269 DNSYLNQLN-ELKETVKQFDDLSVYIL--NDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
++S L ++N EL+ + ++L + + N+++ IE + + +++ + +
Sbjct: 565 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 624
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL----D 381
KK+L+ ++++LE ++ ++ +L+ ++ + +E +T ++E+ + LQ TL D
Sbjct: 625 EKKELERKLSDLEKKMETSHNQCQELKARYERAT---SETKTKHEEILQNLQKTLLDTED 681
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE-QQYEESQTRVNELTVINV-NLSSSK 439
+ A+ L E+EE+R E+A + + + Q E T+ T+ ++ + +
Sbjct: 682 KLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTN 741
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
AK++ EL + + + +EL + E + T +E +E E + + A K
Sbjct: 742 AKLQNELDTLKENNLKNVEELNKSKE----LLTVENQKMEEFRKEIETLKQAAAQKSQQL 797
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
++ +V+L E E KLE + +L E K+R ++ IK +++ L
Sbjct: 798 SALQEENVKLAE-ELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 856
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
QK+IS+ L + ++ + ++ G S + + LE+ +
Sbjct: 857 ----------QKSISITSALLTEKDAELEKLRNEVTVLRG-ENASAKSLHSVVQTLESDK 905
Query: 620 DRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
+ ++ NL L + K +S+ + ++ RA S+++
Sbjct: 906 VKLELKVKNLEL-QLKENKRQLSSSSGNTDTQADEDERAQESQQM 949
Score = 33.9 bits (74), Expect = 1.8
Identities = 52/212 (24%), Positives = 92/212 (43%), Gaps = 27/212 (12%)
Query: 424 RVNELTVINVNLSSSKAKIEQ----------ELAIVAADYDEITKELRIADERYQRVQTE 473
+++ T + L + IEQ E+A + EI +EL +A + + + E
Sbjct: 97 KISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLE 156
Query: 474 LKHTVEHLHEEQERI--VKIEAVKKSLEIEVKNISVRLEEVEANAIV-GGKRIISKLE-A 529
L+ ++ L E K+E + + LE E + + VE +I G +KLE A
Sbjct: 157 LEAKMDQLRTMVEAADREKVELLNQ-LEEEKRKVEDLQFRVEEESITKGDLETQTKLEHA 215
Query: 530 RIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
RIK++E L EK + K +R+L++ + ++ I L+ L Q+V+
Sbjct: 216 RIKELEQSLLFEKTK-------ADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAE 268
Query: 590 YKRQL-----AEQEGMSQQSVTRVRRFQRELE 616
+R+L A MS + + Q +LE
Sbjct: 269 LRRRLESNKPAGDVDMSLSLLQEISSLQEKLE 300
Score = 31.9 bits (69), Expect = 7.5
Identities = 36/166 (21%), Positives = 72/166 (43%), Gaps = 4/166 (2%)
Query: 471 QTELKHTVEHLHE-EQERIVKIEAVKKS-LEIEVKNISVR-LEEVEANAIVGGKRIISKL 527
+ E+ H+ E EQE + + + LE+E K +R + E V + +
Sbjct: 126 RAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEE 185
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+ +++D++ ++EE + + + ++KE+ ++ LQ LE T
Sbjct: 186 KRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVAT 245
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
K ++ E E V V +R LE+ + DV + +LSL++
Sbjct: 246 VSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDV-DMSLSLLQ 290
>BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein.
Length = 913
Score = 68.5 bits (160), Expect = 7e-11
Identities = 103/465 (22%), Positives = 216/465 (46%), Gaps = 53/465 (11%)
Query: 156 YEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYT 215
Y+ ++NL L+Q+ A+ K A +++EE +NV + + + R RD
Sbjct: 442 YDADINL---LKQEHALSASK-----ASSMIEELEQNVCQLKQQLQESELQRKQQLRDQE 493
Query: 216 N---LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSY 272
N + K+ L K + E KA + S + + +T + + + L +
Sbjct: 494 NKFQMEKSHL-KHIYEEKA-HDLQSELDKGKEDTQKK--------IHKFEEALKEKEEQ- 542
Query: 273 LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQI 332
L ++ E++ Q D + L + +Q + E++ A + E K+++++TR K +
Sbjct: 543 LTRVTEVQRLQAQQADAA---LEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREK 599
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
Q E L+ D+++ ++Q + E++ +++ + L L Q+ + S
Sbjct: 600 QSKEFLWQLE-------DIRQRYEQQ---IVELKLEHEQEKTHL---LQQHNAEK---DS 643
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
L + E N E+ LR ++E + + + + + VI ++ + K+ +EL V +
Sbjct: 644 LVRDHEREIENLEKQLRAA-NMEHENQIQEFKKRDAQVI-ADMEAQVHKLREELINVNSQ 701
Query: 453 YDEITKELRIA-DERYQRVQTELKHTVEHLHEEQERIVKIEAVKK---SLEIEVKNISVR 508
+ EL + +E QR E + V L E E++ KIE K E+ ++ + +
Sbjct: 702 RKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKM-KIELKKTHAAETEMTLEKANSK 760
Query: 509 LEEVE---ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQ 565
L+++E + +II++L+ I ++ E +++ ++ +R+K K+ +I+
Sbjct: 761 LKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIR 820
Query: 566 CEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
+ DQ I +LQD LE S +V +++L +E SQ+ +T +R+
Sbjct: 821 -DNDQA-IKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQ 863
Score = 63.7 bits (148), Expect = 2e-09
Identities = 73/392 (18%), Positives = 172/392 (43%), Gaps = 27/392 (6%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
R N E+ + Y ++ +E +ET+++ + ++ D + +Q+ E
Sbjct: 247 RKNNEIEELKTLYRSKQHETEETIRKLEKKVQTLIRDCQVIRETKEDQIAELKKICEQST 306
Query: 320 KSEVTRIKKKLQIQITELELS-LDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+S +KKL + E+E D+ + ++Q+ ++ +++L ++++ Y Q Q
Sbjct: 307 ESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEY---MAQTQS 363
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS 438
T + R+Q LTGE E ++ ++ K +E+ Y+ + + + E+ L
Sbjct: 364 TNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKE 423
Query: 439 KAKI----EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
K + EQ + ++ YD ++ + + + ++ +E L ++ + +++
Sbjct: 424 KDHLVNDYEQNMKLLQTKYD---ADINLLKQEHALSASKASSMIEEL---EQNVCQLKQQ 477
Query: 495 KKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETI----K 550
+ E++ K +L + E + + E + D++ ELD+ K + I +
Sbjct: 478 LQESELQRKQ---QLRDQENKFQMEKSHLKHIYEEKAHDLQSELDKGKEDTQKKIHKFEE 534
Query: 551 ILRKKERQLKEVI----IQCEEDQKNISLLQDSLEKTSQKV-SIYKRQLAEQEG-MSQQS 604
L++KE QL V +Q ++ + + +E S+KV + K Q+ + E +++
Sbjct: 535 ALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSK 594
Query: 605 VTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
R ++ + L ED E + ++ +H
Sbjct: 595 SLREKQSKEFLWQLEDIRQRYEQQIVELKLEH 626
Score = 46.0 bits (104), Expect = 4e-04
Identities = 77/377 (20%), Positives = 161/377 (42%), Gaps = 40/377 (10%)
Query: 297 SSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK 356
S+ + S IE+L V + + +L+ + +++K Q++ E + ++ ++ +I +K
Sbjct: 456 SASKASSMIEELEQNVCQLKQQLQE--SELQRKQQLRDQENKFQMEKSHLKHIYEEKAHD 513
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL--RVKRSV 414
QS E+ ++ Q+++ + + ++ +T EV+ ++ A KR V
Sbjct: 514 LQS----ELDKGKEDTQKKIHKFEEALKEKEEQLTRVT-EVQRLQAQQADAALEEFKRQV 568
Query: 415 EQQYEESQTRVNE-LTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
E E+ + E + + +L+ SK+ E++ E +L +RY++ E
Sbjct: 569 ELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSK-------EFLWQLEDIRQRYEQQIVE 621
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
LK +EH E+ + + A K SL V++ +E +E +L A +
Sbjct: 622 LK--LEHEQEKTHLLQQHNAEKDSL---VRDHEREIENLE-----------KQLRAANME 665
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK----NISLLQDSLEK--TSQKV 587
E ++ E K+R A+ I + + +L+E +I +K + LL++ ++ T +
Sbjct: 666 HENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHE 725
Query: 588 SIYKRQLAEQEGMS-QQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVP 646
+ + AE E M + T + LE A + E + AK +
Sbjct: 726 IVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTT 785
Query: 647 GSQVYLVQESRALSSER 663
S + + L++ER
Sbjct: 786 ISSLKEENSQQQLAAER 802
>AL132825-3|CAI43040.1| 149|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 149
Score = 68.5 bits (160), Expect = 7e-11
Identities = 31/73 (42%), Positives = 49/73 (67%)
Query: 565 QCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADV 624
Q EED+KN++ +QD ++K KV YKRQ E E + ++ + R+ Q EL+ AE+RAD+
Sbjct: 62 QAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADM 121
Query: 625 AESNLSLIRAKHR 637
AE+ + +RA+ R
Sbjct: 122 AETQANKLRARTR 134
Score = 46.0 bits (104), Expect = 4e-04
Identities = 32/113 (28%), Positives = 62/113 (54%), Gaps = 10/113 (8%)
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-----DQKNISLLQDSLEK-TS 584
++++E ELD E+++HAE +K +RK ER++KE+ Q + Q S E
Sbjct: 1 VRELEAELDAEQKKHAEALKGVRKHERRVKELAYQVGDRVSLGSGPGAGPAQASPESPLP 60
Query: 585 QKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR-AKH 636
+ ++ LA + + + ++V+ ++R+ E AE +A+ +NL+ R A+H
Sbjct: 61 AQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQAN---TNLAKYRKAQH 110
>AL132825-1|CAI43042.1| 143|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 143
Score = 68.5 bits (160), Expect = 7e-11
Identities = 31/73 (42%), Positives = 49/73 (67%)
Query: 565 QCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADV 624
Q EED+KN++ +QD ++K KV YKRQ E E + ++ + R+ Q EL+ AE+RAD+
Sbjct: 62 QAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADM 121
Query: 625 AESNLSLIRAKHR 637
AE+ + +RA+ R
Sbjct: 122 AETQANKLRARTR 134
Score = 46.0 bits (104), Expect = 4e-04
Identities = 32/113 (28%), Positives = 62/113 (54%), Gaps = 10/113 (8%)
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-----DQKNISLLQDSLEK-TS 584
++++E ELD E+++HAE +K +RK ER++KE+ Q + Q S E
Sbjct: 1 VRELEAELDAEQKKHAEALKGVRKHERRVKELAYQVGDRVSLGSGPGAGPAQASPESPLP 60
Query: 585 QKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR-AKH 636
+ ++ LA + + + ++V+ ++R+ E AE +A+ +NL+ R A+H
Sbjct: 61 AQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQAN---TNLAKYRKAQH 110
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 68.5 bits (160), Expect = 7e-11
Identities = 82/367 (22%), Positives = 172/367 (46%), Gaps = 31/367 (8%)
Query: 269 DNSYLNQLN-ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIK 327
+NS L + N +LK+T+ F +L+ + L K+ S QL+ +E ++S
Sbjct: 664 ENSELERENRKLKKTLDSFKNLT-FQLESLEKENS----QLDEENLELRRNVESLKCASM 718
Query: 328 KKLQIQITELELSLDVAN-KTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVA 386
K Q+Q+ EL + K ++L K K++ +L D ++LQ TL+ +
Sbjct: 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLEN---S 775
Query: 387 QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
++IQ L E++++ + +++++E+ + S R+ +L N +L +++E++
Sbjct: 776 NKKIQQLESELQDLEMENQT---LQKNLEE-LKISSKRLEQLEKENKSLEQETSQLEKDK 831
Query: 447 AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNIS 506
+ + + ++ I D + + +K + +L +E + + K + K + +K +
Sbjct: 832 KQLEKENKRLRQQAEIKDTTLE--ENNVK--IGNLEKENKTLSKEIGIYKESCVRLKELE 887
Query: 507 VRLEEVEANAIVGGKRIISKLE----ARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+E+ A + K +++ E ++K ++ D EK H E KI KER L +
Sbjct: 888 KENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH-ELEKIGLNKERLLHDE 946
Query: 563 IIQCEEDQKNI------SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
Q +D+ + S L+ SLE +K++ + +L E +QQ ++ ++ E
Sbjct: 947 --QSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYE 1004
Query: 617 AAEDRAD 623
A + R D
Sbjct: 1005 ALKQRQD 1011
Score = 64.5 bits (150), Expect = 1e-09
Identities = 75/350 (21%), Positives = 160/350 (45%), Gaps = 21/350 (6%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S + S+E+ A++ +L+ + ++ Q ++ ++E+ L + N++L
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQ-ELEQMEIELKRLQQENMNLLSDA 302
Query: 356 KKQSLQLTEIQTHYDEVQR--QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ + E+ ++ R +L+ + +Y I+ VEE++ + + L K
Sbjct: 303 RSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTM 362
Query: 414 VEQQYEESQTR---VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
+E Q E ++ R ++EL N+ L + +E E + +E+ +E + ++
Sbjct: 363 LEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI-SVRLEEVEANAIVGGKRIISKLEA 529
E H L + EA +KSL EV + S RL ++E + + +L
Sbjct: 423 MDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-QSLTKTVEELRT 481
Query: 530 RIKDME------LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ +E L++++E +R ++ ++IL + Q K+ + C+ K++ + LEKT
Sbjct: 482 TVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKT 541
Query: 584 SQKV---SIYKRQLAEQEGMS-QQSVTRVRRFQRELEAAEDRA-DVAESN 628
+ + S + ++ EQE Q+V+ +R QR +AE R D+ + N
Sbjct: 542 IETLRENSERQIKILEQENEHLNQTVSSLR--QRSQISAEARVKDIEKEN 589
Score = 62.5 bits (145), Expect = 5e-09
Identities = 104/506 (20%), Positives = 226/506 (44%), Gaps = 45/506 (8%)
Query: 143 KKRMQEIEKELD-LYEKEVNLGSELRQKAAMYRGK----SAKAIAQTLLEESRRNVQNER 197
K+ ++++E EL L ++ +NL S+ R A MYR + KA+ LE S + ER
Sbjct: 278 KQELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLE-SEVSRYKER 335
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
++ +F +R L ++ + L+E+K M T + ++ + E
Sbjct: 336 LHDIEFYKARV------EELKED--NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQL 387
Query: 258 VVRINT-ELPA-IDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA 315
+++ E+ +D + +L E T++ S+ D S E+EQ++ +
Sbjct: 388 KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSM----DESLHLGWELEQISRTSELS 443
Query: 316 ETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR- 374
E KS + + ++ +LE+ KT +L+ T+ ++I E QR
Sbjct: 444 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 503
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+V + + + Q + QSL + ++ ++++++E E S+ ++ L N +
Sbjct: 504 SKKVEILENEIVQEK-QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEH 562
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L+ + + + Q +I+ E R+ D ++ E K E + E ++ KIE
Sbjct: 563 LNQTVSSLRQR--------SQISAEARVKD-----IEKENKILHESIKETSSKLSKIEFE 609
Query: 495 KKSLEIEV---KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
K+ ++ E+ K R EE+E N + ++ L+ +I ++++ ++ + E +
Sbjct: 610 KRQIKKELEHYKEKGERAEELE-NELHHLEKENELLQKKITNLKITCEKIEALEQENSE- 667
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
L ++ R+LK+ + + KN++ +SLEK + ++ +L + + ++ +
Sbjct: 668 LERENRKLKKTL----DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 723
Query: 612 QRELEAAEDRADVAESNLSLIRAKHR 637
Q E + E + + L L++A +
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFK 749
Score = 33.1 bits (72), Expect = 3.2
Identities = 60/373 (16%), Positives = 146/373 (39%), Gaps = 18/373 (4%)
Query: 236 DSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLN-ELKETVKQFDDLSVYIL 294
+S++ ++ +++ ++E R+ +Y QL ELK K ++ L
Sbjct: 957 ESKLESTLKKSLEIKEEKIAALEARLEES-----TNYNQQLRQELKTVKKNYEALKQRQD 1011
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDV---ANKTNI-D 350
+ Q+S I + + + E+ ++K +L I++ +L A KT +
Sbjct: 1012 EERMVQSSPPISGEDNKWERESQETTRELLKVKDRL-IEVERNNATLQAEKQALKTQLKQ 1070
Query: 351 LQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV 410
L+ Q+ +Q +Q Q Q Q +L + + Q L
Sbjct: 1071 LETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1130
Query: 411 KRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
+ S+E + E +L + +L K+E A++Y+ + + ++ +
Sbjct: 1131 QSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNL 1190
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIE-----VKNISVRLEEVEANAIVG-GKRII 524
+ E + + ++ ++ ++E ++K L++E ++N + E + G R+
Sbjct: 1191 EVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLN 1250
Query: 525 SKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS 584
+K+ E+ L + + + + ++ +L+ + +E + + + L
Sbjct: 1251 HTYSQLLKETEV-LQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQC 1309
Query: 585 QKVSIYKRQLAEQ 597
+ +S K L E+
Sbjct: 1310 ELLSQLKGNLEEE 1322
>X05631-1|CAA29119.1| 82|Homo sapiens myosin heavy chain protein.
Length = 82
Score = 68.1 bits (159), Expect = 9e-11
Identities = 33/75 (44%), Positives = 49/75 (65%)
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
EED+KN+ LQ ++K KV YKRQ E E + ++++ R+ Q EL+ AE+RAD+AE
Sbjct: 2 EEDRKNLLRLQALVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAE 61
Query: 627 SNLSLIRAKHRTFVT 641
S ++ +RAK R T
Sbjct: 62 SQVNKLRAKSRDIGT 76
>AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein
protein.
Length = 590
Score = 68.1 bits (159), Expect = 9e-11
Identities = 70/321 (21%), Positives = 156/321 (48%), Gaps = 19/321 (5%)
Query: 298 SKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNI-DLQKTIK 356
++Q +E+ +V K+ +E+ + +K++ +T + + +K + L+ +
Sbjct: 231 AQQADAALEEFKRQVELNSEKVYAEMKKQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQ 290
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
+ Q+ E++ +++ + L L Q+ + SL + E N E+ LR ++E
Sbjct: 291 RYEQQIVELKLEHEQEKTHL---LQQHNAEK---DSLVRDHEREIENLEKQLRAA-NMEH 343
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA-DERYQRVQTELK 475
+ + + + + VI ++ + K+ +EL V + + EL + +E QR E +
Sbjct: 344 ENQIQEFKKRDAQVI-ADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHE 402
Query: 476 HTVEHLHEEQERIVKIEAVKK---SLEIEVKNISVRLEEVE---ANAIVGGKRIISKLEA 529
V L E E++ KIE K E+ ++ + +L+++E + +II++L+
Sbjct: 403 IVVNKLKAESEKM-KIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQT 461
Query: 530 RIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
I ++ E +++ ++ +R+K K+ +I+ + DQ I +LQD LE S +V
Sbjct: 462 TISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIR-DNDQA-IKVLQDELENRSNQVRC 519
Query: 590 YKRQLAEQEGMSQQSVTRVRR 610
+++L +E SQ+ +T +R+
Sbjct: 520 AEKKLQHKELESQEQITYIRQ 540
Score = 50.0 bits (114), Expect = 3e-05
Identities = 57/309 (18%), Positives = 138/309 (44%), Gaps = 26/309 (8%)
Query: 342 DVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
D+ + ++Q+ ++ +++L ++++ Y Q Q T + R+Q LTGE E
Sbjct: 7 DLQKQHTENIQELLEDTNVRLNKMESEY---MAQTQSTNHMIKELEARVQQLTGEAENSN 63
Query: 402 GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI----EQELAIVAADYDEIT 457
++ ++ K +E+ Y+ + + + E+ L K + EQ + ++ YD
Sbjct: 64 LQRQKLIQEKAELERCYQITSSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYD--- 120
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
++ + + + ++ +E L ++ + +++ + E++ K +L + E
Sbjct: 121 ADINLLKQEHALSASKASSMIEEL---EQNVCQLKQQLQESELQRKQ---QLRDQENKFQ 174
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETI----KILRKKERQLKEVI----IQCEED 569
+ + E + D++ ELD+ K + I + L++KE QL V +Q ++
Sbjct: 175 MEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQA 234
Query: 570 QKNISLLQDSLEKTSQKV-SIYKRQLAEQEG-MSQQSVTRVRRFQRELEAAEDRADVAES 627
+ + +E S+KV + K+Q+ + E +++ R ++ + L ED E
Sbjct: 235 DAALEEFKRQVELNSEKVYAEMKKQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQ 294
Query: 628 NLSLIRAKH 636
+ ++ +H
Sbjct: 295 QIVELKLEH 303
Score = 44.8 bits (101), Expect = 0.001
Identities = 64/372 (17%), Positives = 168/372 (45%), Gaps = 32/372 (8%)
Query: 316 ETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQ 375
+TK +++ +K++ + ++ ++ + L++ +++ LQ + Q E + Q
Sbjct: 116 QTKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQ-QLRDQENKFQ 174
Query: 376 LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
++ + ++ + +++ L E+++ + + ++ + ++ EE TRV E V +
Sbjct: 175 MEKSHLKH-IYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTE--VQRLQA 231
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQER--IVKIEA 493
+ A +E+ V + +++ E++ ++ ++V+ +L + + L E+Q + + ++E
Sbjct: 232 QQADAALEEFKRQVELNSEKVYAEMK---KQMEKVEADLTRS-KSLREKQSKEFLWQLED 287
Query: 494 VKKSLEIEVKNISVRLEE----------VEANAIVGG-KRIISKLEARIKDMELE----L 538
+++ E ++ + + E+ E +++V +R I LE +++ +E +
Sbjct: 288 IRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQI 347
Query: 539 DEEKRRHAETIKILRKKERQLKEVIIQCEEDQK----NISLLQDSLEK--TSQKVSIYKR 592
E K+R A+ I + + +L+E +I +K + LL++ ++ T + + +
Sbjct: 348 QEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNK 407
Query: 593 QLAEQEGMS-QQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVY 651
AE E M + T + LE A + E + AK + S +
Sbjct: 408 LKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLK 467
Query: 652 LVQESRALSSER 663
+ L++ER
Sbjct: 468 EENSQQQLAAER 479
>BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein
protein.
Length = 898
Score = 67.7 bits (158), Expect = 1e-10
Identities = 90/407 (22%), Positives = 190/407 (46%), Gaps = 33/407 (8%)
Query: 150 EKE-LDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRT 208
EKE LDL +++ L +LR A K+ I Q E+ R + ++Y+ + T
Sbjct: 319 EKESLDLRKEKETLEKKLRD-ANKELEKNTNKIKQLSQEKGRLH----QLYETK-EGETT 372
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAI 268
+ R+ L +++ + + A N + + +++ET TT + + E I
Sbjct: 373 RLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKET--TTKLTQAKEEADQI 430
Query: 269 DNSYLNQLNELKETVK-QFDDLSVYI------LNDSSKQTSIEIEQLNARVVEAETKLKS 321
+ + + +E+ + + ++L + L ++ S ++E +A++ E E LK
Sbjct: 431 RKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELED-LKR 489
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
+L+ T+++ D +T +L K + + Q EIQ D+V+ T D
Sbjct: 490 TFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-----TAD 544
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
Q Q ++Q E+E ++ E + +++ E S+ R +EL + L+S A+
Sbjct: 545 QL---QEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 601
Query: 442 IEQELAIVAADYDEIT-KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-- 498
++ E + + +D+++ E ++ + Q QT + L EE+ R +++ ++ L
Sbjct: 602 LQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELAC 661
Query: 499 -EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ EVK +S ++EE++ + +V +R K + IKD+ +L + +R+
Sbjct: 662 RQTEVKALSTQVEELK-DELVTQRR---KHASSIKDLTKQLQQARRK 704
Score = 59.7 bits (138), Expect = 3e-08
Identities = 77/367 (20%), Positives = 170/367 (46%), Gaps = 31/367 (8%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
++ + L+E +K+ + +N + KQ IE+LN V + +L ++ K +Q
Sbjct: 228 SEKDNLREELKKRTETEKQHMN-TIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQL 286
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ-RQLQVTLDQYGVAQRRIQS 392
E+ ++ ANK + ++ +K+++ + ++ + + R+ + TL+ ++++
Sbjct: 287 HKEMAQRMEQANKKCEEARQ--EKEAMVMKYVRGEKESLDLRKEKETLE------KKLRD 338
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
E+E+ +Q + K + Q YE T+ E T + + K I + V
Sbjct: 339 ANKELEKNTNKIKQLSQEKGRLHQLYE---TKEGETTRLIREIDKLKEDINSHVIKVKWA 395
Query: 453 YDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
+++ E+ + ++ + +LK T L + +E + + ++K+ + +K EE+
Sbjct: 396 QNKLKAEM----DSHKETKDKLKETTTKLTQAKE---EADQIRKNCQDMIKTYQ-ESEEI 447
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
++N + K ++K E K M+ + D+ + HA+ IK L +R KE + + +
Sbjct: 448 KSNEL-DAKLRVTKGELE-KQMQEKSDQLEMHHAK-IKELEDLKRTFKEGMDELRTLRTK 504
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-------RFQRELEAAEDRADVA 625
+ L+D +T ++S YK + Q+ Q + +V+ + QR + E+ +
Sbjct: 505 VKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEV 564
Query: 626 ESNLSLI 632
ES SLI
Sbjct: 565 ESLNSLI 571
>BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 67.7 bits (158), Expect = 1e-10
Identities = 90/407 (22%), Positives = 190/407 (46%), Gaps = 33/407 (8%)
Query: 150 EKE-LDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRT 208
EKE LDL +++ L +LR A K+ I Q E+ R + ++Y+ + T
Sbjct: 319 EKESLDLRKEKETLEKKLRD-ANKELEKNTNKIKQLSQEKGRLH----QLYETK-EGETT 372
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAI 268
+ R+ L +++ + + A N + + +++ET TT + + E I
Sbjct: 373 RLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKET--TTKLTQAKEEADQI 430
Query: 269 DNSYLNQLNELKETVK-QFDDLSVYI------LNDSSKQTSIEIEQLNARVVEAETKLKS 321
+ + + +E+ + + ++L + L ++ S ++E +A++ E E LK
Sbjct: 431 RKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELED-LKR 489
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
+L+ T+++ D +T +L K + + Q EIQ D+V+ T D
Sbjct: 490 TFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-----TAD 544
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
Q Q ++Q E+E ++ E + +++ E S+ R +EL + L+S A+
Sbjct: 545 QL---QEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 601
Query: 442 IEQELAIVAADYDEIT-KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-- 498
++ E + + +D+++ E ++ + Q QT + L EE+ R +++ ++ L
Sbjct: 602 LQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELAC 661
Query: 499 -EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ EVK +S ++EE++ + +V +R K + IKD+ +L + +R+
Sbjct: 662 RQTEVKALSTQVEELK-DELVTQRR---KHASSIKDLTKQLQQARRK 704
Score = 59.7 bits (138), Expect = 3e-08
Identities = 77/367 (20%), Positives = 170/367 (46%), Gaps = 31/367 (8%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
++ + L+E +K+ + +N + KQ IE+LN V + +L ++ K +Q
Sbjct: 228 SEKDNLREELKKRTETEKQHMN-TIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQL 286
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ-RQLQVTLDQYGVAQRRIQS 392
E+ ++ ANK + ++ +K+++ + ++ + + R+ + TL+ ++++
Sbjct: 287 HKEMAQRMEQANKKCEEARQ--EKEAMVMKYVRGEKESLDLRKEKETLE------KKLRD 338
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
E+E+ +Q + K + Q YE T+ E T + + K I + V
Sbjct: 339 ANKELEKNTNKIKQLSQEKGRLHQLYE---TKEGETTRLIREIDKLKEDINSHVIKVKWA 395
Query: 453 YDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
+++ E+ + ++ + +LK T L + +E + + ++K+ + +K EE+
Sbjct: 396 QNKLKAEM----DSHKETKDKLKETTTKLTQAKE---EADQIRKNCQDMIKTYQ-ESEEI 447
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
++N + K ++K E K M+ + D+ + HA+ IK L +R KE + + +
Sbjct: 448 KSNEL-DAKLRVTKGELE-KQMQEKSDQLEMHHAK-IKELEDLKRTFKEGMDELRTLRTK 504
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-------RFQRELEAAEDRADVA 625
+ L+D +T ++S YK + Q+ Q + +V+ + QR + E+ +
Sbjct: 505 VKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEV 564
Query: 626 ESNLSLI 632
ES SLI
Sbjct: 565 ESLNSLI 571
>BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 67.7 bits (158), Expect = 1e-10
Identities = 90/407 (22%), Positives = 190/407 (46%), Gaps = 33/407 (8%)
Query: 150 EKE-LDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRT 208
EKE LDL +++ L +LR A K+ I Q E+ R + ++Y+ + T
Sbjct: 319 EKESLDLRKEKETLEKKLRD-ANKELEKNTNKIKQLSQEKGRLH----QLYETK-EGETT 372
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAI 268
+ R+ L +++ + + A N + + +++ET TT + + E I
Sbjct: 373 RLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKET--TTKLTQAKEEADQI 430
Query: 269 DNSYLNQLNELKETVK-QFDDLSVYI------LNDSSKQTSIEIEQLNARVVEAETKLKS 321
+ + + +E+ + + ++L + L ++ S ++E +A++ E E LK
Sbjct: 431 RKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELED-LKR 489
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
+L+ T+++ D +T +L K + + Q EIQ D+V+ T D
Sbjct: 490 TFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-----TAD 544
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
Q Q ++Q E+E ++ E + +++ E S+ R +EL + L+S A+
Sbjct: 545 QL---QEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 601
Query: 442 IEQELAIVAADYDEIT-KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-- 498
++ E + + +D+++ E ++ + Q QT + L EE+ R +++ ++ L
Sbjct: 602 LQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELAC 661
Query: 499 -EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ EVK +S ++EE++ + +V +R K + IKD+ +L + +R+
Sbjct: 662 RQTEVKALSTQVEELK-DELVTQRR---KHASSIKDLTKQLQQARRK 704
Score = 61.3 bits (142), Expect = 1e-08
Identities = 78/367 (21%), Positives = 170/367 (46%), Gaps = 31/367 (8%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
++ + L+E +K+ + +N + KQ IE+LN V + KL ++ K +Q
Sbjct: 228 SEKDNLREELKKRTETEKQHMN-TIKQLESRIEELNKEVKASRDKLIAQDVTAKNAVQQL 286
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ-RQLQVTLDQYGVAQRRIQS 392
E+ ++ ANK + ++ +K+++ + ++ + + R+ + TL+ ++++
Sbjct: 287 HKEMAQRMEQANKKCEEARQ--EKEAMVMKYVRGEKESLDLRKEKETLE------KKLRD 338
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
E+E+ +Q + K + Q YE T+ E T + + K I + V
Sbjct: 339 ANKELEKNTNKIKQLSQEKGRLHQLYE---TKEGETTRLIREIDKLKEDINSHVIKVKWA 395
Query: 453 YDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
+++ E+ + ++ + +LK T L + +E + + ++K+ + +K EE+
Sbjct: 396 QNKLKAEM----DSHKETKDKLKETTTKLTQAKE---EADQIRKNCQDMIKTYQ-ESEEI 447
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
++N + K ++K E K M+ + D+ + HA+ IK L +R KE + + +
Sbjct: 448 KSNEL-DAKLRVTKGELE-KQMQEKSDQLEMHHAK-IKELEDLKRTFKEGMDELRTLRTK 504
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-------RFQRELEAAEDRADVA 625
+ L+D +T ++S YK + Q+ Q + +V+ + QR + E+ +
Sbjct: 505 VKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEV 564
Query: 626 ESNLSLI 632
ES SLI
Sbjct: 565 ESLNSLI 571
>BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.
Length = 1004
Score = 67.7 bits (158), Expect = 1e-10
Identities = 90/407 (22%), Positives = 190/407 (46%), Gaps = 33/407 (8%)
Query: 150 EKE-LDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRT 208
EKE LDL +++ L +LR A K+ I Q E+ R + ++Y+ + T
Sbjct: 425 EKESLDLRKEKETLEKKLRD-ANKELEKNTNKIKQLSQEKGRLH----QLYETK-EGETT 478
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAI 268
+ R+ L +++ + + A N + + +++ET TT + + E I
Sbjct: 479 RLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKET--TTKLTQAKEEADQI 536
Query: 269 DNSYLNQLNELKETVK-QFDDLSVYI------LNDSSKQTSIEIEQLNARVVEAETKLKS 321
+ + + +E+ + + ++L + L ++ S ++E +A++ E E LK
Sbjct: 537 RKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELED-LKR 595
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
+L+ T+++ D +T +L K + + Q EIQ D+V+ T D
Sbjct: 596 TFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-----TAD 650
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
Q Q ++Q E+E ++ E + +++ E S+ R +EL + L+S A+
Sbjct: 651 QL---QEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 707
Query: 442 IEQELAIVAADYDEIT-KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-- 498
++ E + + +D+++ E ++ + Q QT + L EE+ R +++ ++ L
Sbjct: 708 LQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELAC 767
Query: 499 -EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ EVK +S ++EE++ + +V +R K + IKD+ +L + +R+
Sbjct: 768 RQTEVKALSTQVEELK-DELVTQRR---KHASSIKDLTKQLQQARRK 810
Score = 59.7 bits (138), Expect = 3e-08
Identities = 77/367 (20%), Positives = 170/367 (46%), Gaps = 31/367 (8%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
++ + L+E +K+ + +N + KQ IE+LN V + +L ++ K +Q
Sbjct: 334 SEKDNLREELKKRTETEKQHMN-TIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQL 392
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ-RQLQVTLDQYGVAQRRIQS 392
E+ ++ ANK + ++ +K+++ + ++ + + R+ + TL+ ++++
Sbjct: 393 HKEMAQRMEQANKKCEEARQ--EKEAMVMKYVRGEKESLDLRKEKETLE------KKLRD 444
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
E+E+ +Q + K + Q YE T+ E T + + K I + V
Sbjct: 445 ANKELEKNTNKIKQLSQEKGRLHQLYE---TKEGETTRLIREIDKLKEDINSHVIKVKWA 501
Query: 453 YDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
+++ E+ + ++ + +LK T L + +E + + ++K+ + +K EE+
Sbjct: 502 QNKLKAEM----DSHKETKDKLKETTTKLTQAKE---EADQIRKNCQDMIKTYQ-ESEEI 553
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
++N + K ++K E K M+ + D+ + HA+ IK L +R KE + + +
Sbjct: 554 KSNEL-DAKLRVTKGELE-KQMQEKSDQLEMHHAK-IKELEDLKRTFKEGMDELRTLRTK 610
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-------RFQRELEAAEDRADVA 625
+ L+D +T ++S YK + Q+ Q + +V+ + QR + E+ +
Sbjct: 611 VKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEV 670
Query: 626 ESNLSLI 632
ES SLI
Sbjct: 671 ESLNSLI 677
>AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen
HD-CL-01 protein.
Length = 613
Score = 67.7 bits (158), Expect = 1e-10
Identities = 90/407 (22%), Positives = 190/407 (46%), Gaps = 33/407 (8%)
Query: 150 EKE-LDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRT 208
EKE LDL +++ L +LR A K+ I Q E+ R + ++Y+ + T
Sbjct: 136 EKESLDLRKEKETLEKKLRD-ANKELEKNTNKIKQLSQEKGRLH----QLYETK-EGETT 189
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAI 268
+ R+ L +++ + + A N + + +++ET TT + + E I
Sbjct: 190 RLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKET--TTKLTQAKEEADQI 247
Query: 269 DNSYLNQLNELKETVK-QFDDLSVYI------LNDSSKQTSIEIEQLNARVVEAETKLKS 321
+ + + +E+ + + ++L + L ++ S ++E +A++ E E LK
Sbjct: 248 RKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELED-LKR 306
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
+L+ T+++ D +T +L K + + Q EIQ D+V+ T D
Sbjct: 307 TFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-----TAD 361
Query: 382 QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
Q Q ++Q E+E ++ E + +++ E S+ R +EL + L+S A+
Sbjct: 362 QL---QEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQ 418
Query: 442 IEQELAIVAADYDEIT-KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-- 498
++ E + + +D+++ E ++ + Q QT + L EE+ R +++ ++ L
Sbjct: 419 LQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELAC 478
Query: 499 -EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR 544
+ EVK +S ++EE++ + +V +R K + IKD+ +L + +R+
Sbjct: 479 RQTEVKALSTQVEELK-DELVTQRR---KHASSIKDLTKQLQQARRK 521
Score = 61.3 bits (142), Expect = 1e-08
Identities = 78/367 (21%), Positives = 170/367 (46%), Gaps = 31/367 (8%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
++ + L+E +K+ + +N + KQ IE+LN V + KL ++ K +Q
Sbjct: 45 SEKDNLREELKKRTETEKQHMN-TIKQLESRIEELNKEVKASRDKLIAQDVTAKNAVQQL 103
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ-RQLQVTLDQYGVAQRRIQS 392
E+ ++ ANK + ++ +K+++ + ++ + + R+ + TL+ ++++
Sbjct: 104 HKEMAQRMEQANKKCEEARQ--EKEAMVMKYVRGEKESLDLRKEKETLE------KKLRD 155
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
E+E+ +Q + K + Q YE T+ E T + + K I + V
Sbjct: 156 ANKELEKNTNKIKQLSQEKGRLHQLYE---TKEGETTRLIREIDKLKEDINSHVIKVKWA 212
Query: 453 YDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
+++ E+ + ++ + +LK T L + +E + + ++K+ + +K EE+
Sbjct: 213 QNKLKAEM----DSHKETKDKLKETTTKLTQAKE---EADQIRKNCQDMIKTYQ-ESEEI 264
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
++N + K ++K E K M+ + D+ + HA+ IK L +R KE + + +
Sbjct: 265 KSNEL-DAKLRVTKGELE-KQMQEKSDQLEMHHAK-IKELEDLKRTFKEGMDELRTLRTK 321
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-------RFQRELEAAEDRADVA 625
+ L+D +T ++S YK + Q+ Q + +V+ + QR + E+ +
Sbjct: 322 VKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEV 381
Query: 626 ESNLSLI 632
ES SLI
Sbjct: 382 ESLNSLI 388
>BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.
Length = 1843
Score = 67.3 bits (157), Expect = 2e-10
Identities = 81/366 (22%), Positives = 170/366 (46%), Gaps = 28/366 (7%)
Query: 269 DNSYLNQLN-ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIK 327
+NS L + N +LK+T+ F +L+ + L K+ S QL+ +E ++S
Sbjct: 664 ENSELERENRKLKKTLDSFKNLT-FQLESLEKENS----QLDEENLELRRNVESLKCASM 718
Query: 328 KKLQIQITELELSLDVAN-KTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVA 386
K Q+Q+ EL + K ++L K K++ +L D ++LQ TL+ +
Sbjct: 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLEN---S 775
Query: 387 QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
++IQ L E++++ + +++++E+ + S R+ +L N +L +++E++
Sbjct: 776 NKKIQQLESELQDLEMENQT---LQKNLEE-LKISSKRLEQLEKENKSLEQETSQLEKDK 831
Query: 447 AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNIS 506
+ + + ++ I D + + +K + +L +E + + K + K + +K +
Sbjct: 832 KQLEKENKRLRQQAEIKDTTLE--ENNVK--IGNLEKENKTLSKEIGIYKESCVRLKELE 887
Query: 507 VRLEEVEANAIVGGKRIISKLE----ARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+E+ A + K +++ E ++K ++ D EK H E KI KER L +
Sbjct: 888 KENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH-ELEKIGLNKERLLHDE 946
Query: 563 IIQCEEDQKNI-----SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
+ K + S L+ SLE +K++ + +L E +QQ ++ ++ EA
Sbjct: 947 QSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEA 1006
Query: 618 AEDRAD 623
+ R D
Sbjct: 1007 LKQRQD 1012
Score = 64.5 bits (150), Expect = 1e-09
Identities = 75/350 (21%), Positives = 160/350 (45%), Gaps = 21/350 (6%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S + S+E+ A++ +L+ + ++ Q ++ ++E+ L + N++L
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQ-ELEQMEIELKRLQQENMNLLSDA 302
Query: 356 KKQSLQLTEIQTHYDEVQR--QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ + E+ ++ R +L+ + +Y I+ VEE++ + + L K
Sbjct: 303 RSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTM 362
Query: 414 VEQQYEESQTR---VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
+E Q E ++ R ++EL N+ L + +E E + +E+ +E + ++
Sbjct: 363 LEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI-SVRLEEVEANAIVGGKRIISKLEA 529
E H L + EA +KSL EV + S RL ++E + + +L
Sbjct: 423 MDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-QSLTKTVEELRT 481
Query: 530 RIKDME------LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ +E L++++E +R ++ ++IL + Q K+ + C+ K++ + LEKT
Sbjct: 482 TVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKT 541
Query: 584 SQKV---SIYKRQLAEQEGMS-QQSVTRVRRFQRELEAAEDRA-DVAESN 628
+ + S + ++ EQE Q+V+ +R QR +AE R D+ + N
Sbjct: 542 IETLRENSERQIKILEQENEHLNQTVSSLR--QRSQISAEARVKDIEKEN 589
Score = 62.5 bits (145), Expect = 5e-09
Identities = 104/506 (20%), Positives = 226/506 (44%), Gaps = 45/506 (8%)
Query: 143 KKRMQEIEKELD-LYEKEVNLGSELRQKAAMYRGK----SAKAIAQTLLEESRRNVQNER 197
K+ ++++E EL L ++ +NL S+ R A MYR + KA+ LE S + ER
Sbjct: 278 KQELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLE-SEVSRYKER 335
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
++ +F +R L ++ + L+E+K M T + ++ + E
Sbjct: 336 LHDIEFYKARV------EELKED--NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQL 387
Query: 258 VVRINT-ELPA-IDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA 315
+++ E+ +D + +L E T++ S+ D S E+EQ++ +
Sbjct: 388 KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSM----DESLHLGWELEQISRTSELS 443
Query: 316 ETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR- 374
E KS + + ++ +LE+ KT +L+ T+ ++I E QR
Sbjct: 444 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 503
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+V + + + Q + QSL + ++ ++++++E E S+ ++ L N +
Sbjct: 504 SKKVEILENEIVQEK-QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEH 562
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L+ + + + Q +I+ E R+ D ++ E K E + E ++ KIE
Sbjct: 563 LNQTVSSLRQR--------SQISAEARVKD-----IEKENKILHESIKETSSKLSKIEFE 609
Query: 495 KKSLEIEV---KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
K+ ++ E+ K R EE+E N + ++ L+ +I ++++ ++ + E +
Sbjct: 610 KRQIKKELEHYKEKGERAEELE-NELHHLEKENELLQKKITNLKITCEKIEALEQENSE- 667
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
L ++ R+LK+ + + KN++ +SLEK + ++ +L + + ++ +
Sbjct: 668 LERENRKLKKTL----DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 723
Query: 612 QRELEAAEDRADVAESNLSLIRAKHR 637
Q E + E + + L L++A +
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFK 749
Score = 36.3 bits (80), Expect = 0.35
Identities = 77/464 (16%), Positives = 187/464 (40%), Gaps = 33/464 (7%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
R++E+EKE K + +++ + ++ + + + +E + K
Sbjct: 882 RLKELEKENKELVKRATI--DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE-LEKIGLN 938
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
R L + T+ S+ L ++ +ES S + + + R+ E+ T ++ E
Sbjct: 939 KERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEES--TNYNQQLRQE 996
Query: 265 LPAIDNSY--LNQLNELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLNARVVEAETKLK 320
L + +Y L Q + + V+ +S S++T+ E+ ++ R++E E
Sbjct: 997 LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN-N 1055
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQ-KTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+ + K+ L+ Q+ +LE N+ Q +++Q++ L E T +LQV
Sbjct: 1056 ATLQAEKQALKTQLKQLE-----TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV- 1109
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+L + + Q L + S+E + E +L + +L
Sbjct: 1110 ---------ENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDH 1160
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
K+E A++Y+ + + ++ ++ E + + ++ ++ ++E ++K L+
Sbjct: 1161 EKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLK 1220
Query: 500 IE-----VKNISVRLEEVEANAIVG-GKRIISKLEARIKDMELELDEEKRRHAETIKILR 553
+E ++N + E + G R+ +K+ E+ L + + + +
Sbjct: 1221 VEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEV-LQTDHKNLKSLLNNSK 1279
Query: 554 KKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
++ +L+ + +E + + + L + +S K L E+
Sbjct: 1280 LEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEE 1323
>BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.
Length = 1726
Score = 67.3 bits (157), Expect = 2e-10
Identities = 92/506 (18%), Positives = 219/506 (43%), Gaps = 32/506 (6%)
Query: 145 RMQEIEKELDLYEKEVNLGSELR-----QKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
+++++E ++++ ++E++ E++ QK R + + EE RRN + +Y
Sbjct: 768 KIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA--DTLY 825
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMN-SCDSRVTES-ITETVRVRETSPTTC 257
+ R + R K V K +E + R +S + + V+ R +
Sbjct: 826 ----EKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 881
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
N + D N L++ KE + + N S + ++ N+ + E
Sbjct: 882 SREQNARMLQ-DGILTNHLSKQKEI--EMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIA 938
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
L+ E+ IK + Q + + L + + N DLQKTIK+ LT+ + Y+ +L
Sbjct: 939 MLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYN---GRLS 995
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
V + + ++++ E + E + ++S+T EL +
Sbjct: 996 VLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARD 1055
Query: 438 SKAKIEQELAIVAA---DYDEI-TKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
++++ ++ + D +EI +++L + + ++ E HT + L E+ + +++
Sbjct: 1056 ECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQK 1115
Query: 494 VKKSLEIEVKNISVRL--EEVEANAIVGGKRII----SKLEARIKDMELELDEEKRRHAE 547
+ ++K + + E+V+ N +G + + S+L++ + +LD+ +
Sbjct: 1116 DLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADN 1175
Query: 548 TIKILRKKERQLKEVI--IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
K + + Q ++ +Q E +++++ L + + E S+ + +RQ + +++ V
Sbjct: 1176 KEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREV 1235
Query: 606 TRVRRFQRELEAAEDRADVAESNLSL 631
VR+ Q+EL + ++E++L +
Sbjct: 1236 V-VRQLQQELADTLKKQSMSEASLEV 1260
Score = 54.4 bits (125), Expect = 1e-06
Identities = 52/271 (19%), Positives = 120/271 (44%), Gaps = 13/271 (4%)
Query: 399 EIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
E++ N+ + L VK + +E + Q ++E I L K + E+EL + ++
Sbjct: 756 ELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEE 815
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
++ R AD Y++++ +L+ E +E E ++E ++LE+E++ + L N +
Sbjct: 816 EKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNL-----NQV 870
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNI---- 573
V + + +R ++ + D H K + ++++ E++K++
Sbjct: 871 VQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKN 930
Query: 574 SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
S+LQ+ + ++ K Q E+E + + V+ +L+ + E L+
Sbjct: 931 SMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ---NEETLTQTI 987
Query: 634 AKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
+++ ++ T + + E+ S ERL
Sbjct: 988 SQYNGRLSVLTAENAMLNSKLENEKQSKERL 1018
Score = 51.6 bits (118), Expect = 9e-06
Identities = 98/467 (20%), Positives = 194/467 (41%), Gaps = 45/467 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQ-KAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
QK + + ++ L L E+ L SE K Y+ ++ KA + ++ + ++ + + +
Sbjct: 1192 QKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQ 1251
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
+AS + +R NL E++ + ++ + E + R T C +
Sbjct: 1252 SMSEASLEVTSRYRINLED--------ETQDLKKKLGQIRNQLQEA-QDRHTEAVRCAEK 1302
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
+ ++ +K+ + + ++L +LN + + E EQL +++E + L+
Sbjct: 1303 MQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSED--EKEQLK-KLMELKQSLE 1359
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKK-QSLQLTEIQTHYDEVQRQLQVT 379
+ + KK +EL ++ N+ L+ T KK + E H D Q ++
Sbjct: 1360 CNLDQEMKK------NVELEREITGFKNL-LKMTRKKLNEYENGEFSFHGDLKTSQFEMD 1412
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ Q + +I LT E+E G+ L K + Q+ S V + L +K
Sbjct: 1413 I-QINKLKHKIDDLTAELETA-GSKCLHLDTKNQILQEELLSMKTVQKKCE---KLQKNK 1467
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
K+EQE+ + + + EL + Q ++ + QE K++ V L+
Sbjct: 1468 KKLEQEVINLRSHIERNMVELGQVKQYKQEIEERAR---------QEIAEKLKEVNLFLQ 1518
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ + LE+ N K S++E RIKD+E EL + K + K +K +QL
Sbjct: 1519 AQAAS-QENLEQFRENNFASMK---SQMELRIKDLESELSKIKTSQEDFNKTELEKYKQL 1574
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
E+ K L L KT+++++ +L ++ S+ T
Sbjct: 1575 ------YLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFT 1615
Score = 48.4 bits (110), Expect = 8e-05
Identities = 84/371 (22%), Positives = 155/371 (41%), Gaps = 35/371 (9%)
Query: 270 NSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKK 329
N Y+ + ++E + Q ++ +L + + V+ + + + I +K
Sbjct: 1139 NKYIGKQESVEERLSQLQSENM-LLRQQLDDAHNKADNKEKTVINIQDQFHA----IVQK 1193
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
LQ + + L L+ NK I +K++ Q + + V RQLQ L Q
Sbjct: 1194 LQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSM 1253
Query: 390 IQSLTGEVEEIRGNYE---QALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKIEQE 445
++ R N E Q L+ K + Q +E+Q R E + K K+E++
Sbjct: 1254 SEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKD 1313
Query: 446 LAIVAADY-------DEITKELRIA----DERYQ-RVQTELKHTVE-HLHEEQERIVKIE 492
A + +E+ K L A DE+ Q + ELK ++E +L +E ++ V++E
Sbjct: 1314 NAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELE 1373
Query: 493 AVKKSLEIEVKNISVRLEEVEAN--AIVGGKRI--------ISKLEARIKDM--ELELDE 540
+ +K +L E E + G + I+KL+ +I D+ ELE
Sbjct: 1374 REITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAG 1433
Query: 541 EKRRHAETI-KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
K H +T +IL+++ +K V +CE+ QKN L+ + + +L + +
Sbjct: 1434 SKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQ 1493
Query: 600 MSQQSVTRVRR 610
Q+ R R+
Sbjct: 1494 YKQEIEERARQ 1504
Score = 42.3 bits (95), Expect = 0.005
Identities = 73/351 (20%), Positives = 154/351 (43%), Gaps = 36/351 (10%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNI--------DLQKTI-K 356
E++ ++ E + + EV +K++L++ + LE+ L K+N+ D Q+ + +
Sbjct: 826 EKIREQLRRKEEQYRKEV-EVKQQLELSLQTLEMELRTV-KSNLNQVVQERNDAQRQLSR 883
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
+Q+ ++ + + + +Q ++ + AQ+++ S E E+ L K S+ Q
Sbjct: 884 EQNARMLQDGILTNHLSKQKEIEM-----AQKKMNSENSHSHE----EEKDLSHKNSMLQ 934
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ E + R+ T+ N N K K ++L IV +++ K ++ +E + ++
Sbjct: 935 E-EIAMLRLEIDTIKNQNQEKEK-KCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNG 992
Query: 477 TVEHLHEEQERI-VKIEAVKKS---LEIEVKNISVRLEEV--EANAIVGGKRIISKLEAR 530
+ L E + K+E K+S LE EV++ RL + + KR + R
Sbjct: 993 RLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQR 1052
Query: 531 IKD--------MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
+D M ++ K + + L K E +L + I+ + + LE+
Sbjct: 1053 ARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLER 1112
Query: 583 TSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
+ +S + Q+ E E Q +V ++ + E+ E+R +S L+R
Sbjct: 1113 VQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLR 1163
>AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.
Length = 1710
Score = 67.3 bits (157), Expect = 2e-10
Identities = 92/506 (18%), Positives = 219/506 (43%), Gaps = 32/506 (6%)
Query: 145 RMQEIEKELDLYEKEVNLGSELR-----QKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
+++++E ++++ ++E++ E++ QK R + + EE RRN + +Y
Sbjct: 752 KIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA--DTLY 809
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMN-SCDSRVTES-ITETVRVRETSPTTC 257
+ R + R K V K +E + R +S + + V+ R +
Sbjct: 810 ----EKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 865
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
N + D N L++ KE + + N S + ++ N+ + E
Sbjct: 866 SREQNARMLQ-DGILTNHLSKQKEI--EMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIA 922
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
L+ E+ IK + Q + + L + + N DLQKTIK+ LT+ + Y+ +L
Sbjct: 923 MLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYN---GRLS 979
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
V + + ++++ E + E + ++S+T EL +
Sbjct: 980 VLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARD 1039
Query: 438 SKAKIEQELAIVAA---DYDEI-TKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
++++ ++ + D +EI +++L + + ++ E HT + L E+ + +++
Sbjct: 1040 ECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQK 1099
Query: 494 VKKSLEIEVKNISVRL--EEVEANAIVGGKRII----SKLEARIKDMELELDEEKRRHAE 547
+ ++K + + E+V+ N +G + + S+L++ + +LD+ +
Sbjct: 1100 DLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADN 1159
Query: 548 TIKILRKKERQLKEVI--IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
K + + Q ++ +Q E +++++ L + + E S+ + +RQ + +++ V
Sbjct: 1160 KEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREV 1219
Query: 606 TRVRRFQRELEAAEDRADVAESNLSL 631
VR+ Q+EL + ++E++L +
Sbjct: 1220 V-VRQLQQELADTLKKQSMSEASLEV 1244
Score = 54.4 bits (125), Expect = 1e-06
Identities = 52/271 (19%), Positives = 120/271 (44%), Gaps = 13/271 (4%)
Query: 399 EIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
E++ N+ + L VK + +E + Q ++E I L K + E+EL + ++
Sbjct: 740 ELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEE 799
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
++ R AD Y++++ +L+ E +E E ++E ++LE+E++ + L N +
Sbjct: 800 EKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNL-----NQV 854
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNI---- 573
V + + +R ++ + D H K + ++++ E++K++
Sbjct: 855 VQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKN 914
Query: 574 SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
S+LQ+ + ++ K Q E+E + + V+ +L+ + E L+
Sbjct: 915 SMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ---NEETLTQTI 971
Query: 634 AKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
+++ ++ T + + E+ S ERL
Sbjct: 972 SQYNGRLSVLTAENAMLNSKLENEKQSKERL 1002
Score = 51.6 bits (118), Expect = 9e-06
Identities = 98/467 (20%), Positives = 194/467 (41%), Gaps = 45/467 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQ-KAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
QK + + ++ L L E+ L SE K Y+ ++ KA + ++ + ++ + + +
Sbjct: 1176 QKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQ 1235
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
+AS + +R NL E++ + ++ + E + R T C +
Sbjct: 1236 SMSEASLEVTSRYRINLED--------ETQDLKKKLGQIRNQLQEA-QDRHTEAVRCAEK 1286
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
+ ++ +K+ + + ++L +LN + + E EQL +++E + L+
Sbjct: 1287 MQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSED--EKEQLK-KLMELKQSLE 1343
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKK-QSLQLTEIQTHYDEVQRQLQVT 379
+ + KK +EL ++ N+ L+ T KK + E H D Q ++
Sbjct: 1344 CNLDQEMKK------NVELEREITGFKNL-LKMTRKKLNEYENGEFSFHGDLKTSQFEMD 1396
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ Q + +I LT E+E G+ L K + Q+ S V + L +K
Sbjct: 1397 I-QINKLKHKIDDLTAELETA-GSKCLHLDTKNQILQEELLSMKTVQKKCE---KLQKNK 1451
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
K+EQE+ + + + EL + Q ++ + QE K++ V L+
Sbjct: 1452 KKLEQEVINLRSHIERNMVELGQVKQYKQEIEERAR---------QEIAEKLKEVNLFLQ 1502
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ + LE+ N K S++E RIKD+E EL + K + K +K +QL
Sbjct: 1503 AQAAS-QENLEQFRENNFASMK---SQMELRIKDLESELSKIKTSQEDFNKTELEKYKQL 1558
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
E+ K L L KT+++++ +L ++ S+ T
Sbjct: 1559 ------YLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFT 1599
Score = 48.4 bits (110), Expect = 8e-05
Identities = 84/371 (22%), Positives = 155/371 (41%), Gaps = 35/371 (9%)
Query: 270 NSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKK 329
N Y+ + ++E + Q ++ +L + + V+ + + + I +K
Sbjct: 1123 NKYIGKQESVEERLSQLQSENM-LLRQQLDDAHNKADNKEKTVINIQDQFHA----IVQK 1177
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
LQ + + L L+ NK I +K++ Q + + V RQLQ L Q
Sbjct: 1178 LQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSM 1237
Query: 390 IQSLTGEVEEIRGNYE---QALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKIEQE 445
++ R N E Q L+ K + Q +E+Q R E + K K+E++
Sbjct: 1238 SEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKD 1297
Query: 446 LAIVAADY-------DEITKELRIA----DERYQ-RVQTELKHTVE-HLHEEQERIVKIE 492
A + +E+ K L A DE+ Q + ELK ++E +L +E ++ V++E
Sbjct: 1298 NAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELE 1357
Query: 493 AVKKSLEIEVKNISVRLEEVEAN--AIVGGKRI--------ISKLEARIKDM--ELELDE 540
+ +K +L E E + G + I+KL+ +I D+ ELE
Sbjct: 1358 REITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAG 1417
Query: 541 EKRRHAETI-KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
K H +T +IL+++ +K V +CE+ QKN L+ + + +L + +
Sbjct: 1418 SKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQ 1477
Query: 600 MSQQSVTRVRR 610
Q+ R R+
Sbjct: 1478 YKQEIEERARQ 1488
Score = 42.3 bits (95), Expect = 0.005
Identities = 73/351 (20%), Positives = 154/351 (43%), Gaps = 36/351 (10%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNI--------DLQKTI-K 356
E++ ++ E + + EV +K++L++ + LE+ L K+N+ D Q+ + +
Sbjct: 810 EKIREQLRRKEEQYRKEV-EVKQQLELSLQTLEMELRTV-KSNLNQVVQERNDAQRQLSR 867
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
+Q+ ++ + + + +Q ++ + AQ+++ S E E+ L K S+ Q
Sbjct: 868 EQNARMLQDGILTNHLSKQKEIEM-----AQKKMNSENSHSHE----EEKDLSHKNSMLQ 918
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ E + R+ T+ N N K K ++L IV +++ K ++ +E + ++
Sbjct: 919 E-EIAMLRLEIDTIKNQNQEKEK-KCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNG 976
Query: 477 TVEHLHEEQERI-VKIEAVKKS---LEIEVKNISVRLEEV--EANAIVGGKRIISKLEAR 530
+ L E + K+E K+S LE EV++ RL + + KR + R
Sbjct: 977 RLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQR 1036
Query: 531 IKD--------MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
+D M ++ K + + L K E +L + I+ + + LE+
Sbjct: 1037 ARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLER 1096
Query: 583 TSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
+ +S + Q+ E E Q +V ++ + E+ E+R +S L+R
Sbjct: 1097 VQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLR 1147
>AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens
cDNA FLJ46736 fis, clone TRACH3020769, weakly similar
to Myosin heavy chain, nonmuscle type B. ).
Length = 1080
Score = 67.3 bits (157), Expect = 2e-10
Identities = 92/506 (18%), Positives = 219/506 (43%), Gaps = 32/506 (6%)
Query: 145 RMQEIEKELDLYEKEVNLGSELR-----QKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
+++++E ++++ ++E++ E++ QK R + + EE RRN + +Y
Sbjct: 309 KIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA--DTLY 366
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMN-SCDSRVTES-ITETVRVRETSPTTC 257
+ R + R K V K +E + R +S + + V+ R +
Sbjct: 367 ----EKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 422
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
N + D N L++ KE + + N S + ++ N+ + E
Sbjct: 423 SREQNARMLQ-DGILTNHLSKQKEI--EMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIA 479
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
L+ E+ IK + Q + + L + + N DLQKTIK+ LT+ + Y+ +L
Sbjct: 480 MLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYN---GRLS 536
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
V + + ++++ E + E + ++S+T EL +
Sbjct: 537 VLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARD 596
Query: 438 SKAKIEQELAIVAA---DYDEI-TKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
++++ ++ + D +EI +++L + + ++ E HT + L E+ + +++
Sbjct: 597 ECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQK 656
Query: 494 VKKSLEIEVKNISVRL--EEVEANAIVGGKRII----SKLEARIKDMELELDEEKRRHAE 547
+ ++K + + E+V+ N +G + + S+L++ + +LD+ +
Sbjct: 657 DLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADN 716
Query: 548 TIKILRKKERQLKEVI--IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
K + + Q ++ +Q E +++++ L + + E S+ + +RQ + +++ V
Sbjct: 717 KEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREV 776
Query: 606 TRVRRFQRELEAAEDRADVAESNLSL 631
VR+ Q+EL + ++E++L +
Sbjct: 777 V-VRQLQQELADTLKKQSMSEASLEV 801
Score = 54.4 bits (125), Expect = 1e-06
Identities = 52/271 (19%), Positives = 120/271 (44%), Gaps = 13/271 (4%)
Query: 399 EIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
E++ N+ + L VK + +E + Q ++E I L K + E+EL + ++
Sbjct: 297 ELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEE 356
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
++ R AD Y++++ +L+ E +E E ++E ++LE+E++ + L N +
Sbjct: 357 EKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNL-----NQV 411
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNI---- 573
V + + +R ++ + D H K + ++++ E++K++
Sbjct: 412 VQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKN 471
Query: 574 SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
S+LQ+ + ++ K Q E+E + + V+ +L+ + E L+
Sbjct: 472 SMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ---NEETLTQTI 528
Query: 634 AKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
+++ ++ T + + E+ S ERL
Sbjct: 529 SQYNGRLSVLTAENAMLNSKLENEKQSKERL 559
Score = 48.0 bits (109), Expect = 1e-04
Identities = 84/371 (22%), Positives = 155/371 (41%), Gaps = 35/371 (9%)
Query: 270 NSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKK 329
N Y+ + ++E + Q ++ +L + + V+ + + + I +K
Sbjct: 680 NKYIGKQESVEERLSQLQSENM-LLRQQLDDAHNKADNKEKTVINIQDQFHA----IVQK 734
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
LQ + + L L+ NK I +K++ Q + + V RQLQ L Q
Sbjct: 735 LQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSM 794
Query: 390 IQSLTGEVEEIRGNYE---QALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKIEQE 445
++ R N E Q L+ K + Q +E+Q R E + K K+E++
Sbjct: 795 SEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKD 854
Query: 446 LAIVAADY-------DEITKELRIA----DERYQ-RVQTELKHTVE-HLHEEQERIVKIE 492
A + +E+ K L A DE+ Q + ELK ++E +L +E ++ V++E
Sbjct: 855 NAKLKVTIKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLGQEMKKNVELE 914
Query: 493 AVKKSLEIEVKNISVRLEEVEAN--AIVGGKRI--------ISKLEARIKDM--ELELDE 540
+ +K +L E E + G + I+KL+ +I D+ ELE
Sbjct: 915 REITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAG 974
Query: 541 EKRRHAETI-KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
K H +T +IL+++ +K V +CE+ QKN L+ + + +L + +
Sbjct: 975 SKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQ 1034
Query: 600 MSQQSVTRVRR 610
Q+ R R+
Sbjct: 1035 YKQEIEERARQ 1045
Score = 45.2 bits (102), Expect = 7e-04
Identities = 73/417 (17%), Positives = 175/417 (41%), Gaps = 31/417 (7%)
Query: 150 EKELDLYEKEVNLGSE-LRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQA--- 205
EK DL +K + E L Q + Y G+ + A+ + S+ ++NE+ K +A
Sbjct: 508 EKNEDL-QKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSK--LENEKQSKERLEAEVE 564
Query: 206 ------SRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETV-RVRETSPTTCV 258
+ + +RD + SK L A +A + C SR+ + + V +++ +
Sbjct: 565 SYHSRLAAAIHDRDQSETSKRELELAFQ--RARDEC-SRLQDKMNFDVSNLKDNNEILSQ 621
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
TE NS + + ++ +++ L + + QT +++++ + + K
Sbjct: 622 QLFKTESKL--NSLEIEFHHTRDALRE-KTLGLERVQKDLSQTQCQMKEMEQKYQNEQVK 678
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ + + ++ ++ ++++L+ + + D + + IQ + + ++LQ
Sbjct: 679 VNKYIGK-QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQA 737
Query: 379 TLDQYGVA-QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
++ + + R + L E ++ Q K E + Q + + T+ ++S
Sbjct: 738 ESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELAD-TLKKQSMSE 796
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHT--VEHLHEEQERIVKIEAVK 495
+ ++ I D + K+ ++ R Q + + +HT V + Q+ K+E
Sbjct: 797 ASLEVTSRYRINLEDETQDLKK-KLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDN 855
Query: 496 KSLEIEVKNISVRLEEVEANAIVGG-----KRIISKLEARIKDMELELDEEKRRHAE 547
L++ +K ++EE++ N + K + KL + +E L +E +++ E
Sbjct: 856 AKLKVTIKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLGQEMKKNVE 912
Score = 42.3 bits (95), Expect = 0.005
Identities = 73/351 (20%), Positives = 154/351 (43%), Gaps = 36/351 (10%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNI--------DLQKTI-K 356
E++ ++ E + + EV +K++L++ + LE+ L K+N+ D Q+ + +
Sbjct: 367 EKIREQLRRKEEQYRKEV-EVKQQLELSLQTLEMELRTV-KSNLNQVVQERNDAQRQLSR 424
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
+Q+ ++ + + + +Q ++ + AQ+++ S E E+ L K S+ Q
Sbjct: 425 EQNARMLQDGILTNHLSKQKEIEM-----AQKKMNSENSHSHE----EEKDLSHKNSMLQ 475
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ E + R+ T+ N N K K ++L IV +++ K ++ +E + ++
Sbjct: 476 E-EIAMLRLEIDTIKNQNQEKEK-KCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNG 533
Query: 477 TVEHLHEEQERI-VKIEAVKKS---LEIEVKNISVRLEEV--EANAIVGGKRIISKLEAR 530
+ L E + K+E K+S LE EV++ RL + + KR + R
Sbjct: 534 RLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQR 593
Query: 531 IKD--------MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
+D M ++ K + + L K E +L + I+ + + LE+
Sbjct: 594 ARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLER 653
Query: 583 TSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
+ +S + Q+ E E Q +V ++ + E+ E+R +S L+R
Sbjct: 654 VQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLR 704
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 67.3 bits (157), Expect = 2e-10
Identities = 81/366 (22%), Positives = 170/366 (46%), Gaps = 28/366 (7%)
Query: 269 DNSYLNQLN-ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIK 327
+NS L + N +LK+T+ F +L+ + L K+ S QL+ +E ++S
Sbjct: 664 ENSELERENRKLKKTLDSFKNLT-FQLESLEKENS----QLDEENLELRRNVESLKCASM 718
Query: 328 KKLQIQITELELSLDVAN-KTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVA 386
K Q+Q+ EL + K ++L K K++ +L D ++LQ TL+ +
Sbjct: 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLEN---S 775
Query: 387 QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
++IQ L E++++ + +++++E+ + S R+ +L N +L +++E++
Sbjct: 776 NKKIQQLESELQDLEMENQT---LQKNLEE-LKISSKRLEQLEKENKSLEQETSQLEKDK 831
Query: 447 AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNIS 506
+ + + ++ I D + + +K + +L +E + + K + K + +K +
Sbjct: 832 KQLEKENKRLRQQAEIKDTTLE--ENNVK--IGNLEKENKTLSKEIGIYKESCVRLKELE 887
Query: 507 VRLEEVEANAIVGGKRIISKLE----ARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+E+ A + K +++ E ++K ++ D EK H E KI KER L +
Sbjct: 888 KENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH-ELEKIGLNKERLLHDE 946
Query: 563 IIQCEEDQKNI-----SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
+ K + S L+ SLE +K++ + +L E +QQ ++ ++ EA
Sbjct: 947 QSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEA 1006
Query: 618 AEDRAD 623
+ R D
Sbjct: 1007 LKQRQD 1012
Score = 64.5 bits (150), Expect = 1e-09
Identities = 75/350 (21%), Positives = 160/350 (45%), Gaps = 21/350 (6%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S + S+E+ A++ +L+ + ++ Q ++ ++E+ L + N++L
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQ-ELEQMEIELKRLQQENMNLLSDA 302
Query: 356 KKQSLQLTEIQTHYDEVQR--QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ + E+ ++ R +L+ + +Y I+ VEE++ + + L K
Sbjct: 303 RSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTM 362
Query: 414 VEQQYEESQTR---VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
+E Q E ++ R ++EL N+ L + +E E + +E+ +E + ++
Sbjct: 363 LEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI-SVRLEEVEANAIVGGKRIISKLEA 529
E H L + EA +KSL EV + S RL ++E + + +L
Sbjct: 423 MDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-QSLTKTVEELRT 481
Query: 530 RIKDME------LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ +E L++++E +R ++ ++IL + Q K+ + C+ K++ + LEKT
Sbjct: 482 TVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKT 541
Query: 584 SQKV---SIYKRQLAEQEGMS-QQSVTRVRRFQRELEAAEDRA-DVAESN 628
+ + S + ++ EQE Q+V+ +R QR +AE R D+ + N
Sbjct: 542 IETLRENSERQIKILEQENEHLNQTVSSLR--QRSQISAEARVKDIEKEN 589
Score = 62.5 bits (145), Expect = 5e-09
Identities = 104/506 (20%), Positives = 226/506 (44%), Gaps = 45/506 (8%)
Query: 143 KKRMQEIEKELD-LYEKEVNLGSELRQKAAMYRGK----SAKAIAQTLLEESRRNVQNER 197
K+ ++++E EL L ++ +NL S+ R A MYR + KA+ LE S + ER
Sbjct: 278 KQELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLE-SEVSRYKER 335
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
++ +F +R L ++ + L+E+K M T + ++ + E
Sbjct: 336 LHDIEFYKARV------EELKED--NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQL 387
Query: 258 VVRINT-ELPA-IDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA 315
+++ E+ +D + +L E T++ S+ D S E+EQ++ +
Sbjct: 388 KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSM----DESLHLGWELEQISRTSELS 443
Query: 316 ETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR- 374
E KS + + ++ +LE+ KT +L+ T+ ++I E QR
Sbjct: 444 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 503
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+V + + + Q + QSL + ++ ++++++E E S+ ++ L N +
Sbjct: 504 SKKVEILENEIVQEK-QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEH 562
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L+ + + + Q +I+ E R+ D ++ E K E + E ++ KIE
Sbjct: 563 LNQTVSSLRQR--------SQISAEARVKD-----IEKENKILHESIKETSSKLSKIEFE 609
Query: 495 KKSLEIEV---KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
K+ ++ E+ K R EE+E N + ++ L+ +I ++++ ++ + E +
Sbjct: 610 KRQIKKELEHYKEKGERAEELE-NELHHLEKENELLQKKITNLKITCEKIEALEQENSE- 667
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
L ++ R+LK+ + + KN++ +SLEK + ++ +L + + ++ +
Sbjct: 668 LERENRKLKKTL----DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 723
Query: 612 QRELEAAEDRADVAESNLSLIRAKHR 637
Q E + E + + L L++A +
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFK 749
Score = 36.3 bits (80), Expect = 0.35
Identities = 77/464 (16%), Positives = 187/464 (40%), Gaps = 33/464 (7%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
R++E+EKE K + +++ + ++ + + + +E + K
Sbjct: 882 RLKELEKENKELVKRATI--DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE-LEKIGLN 938
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
R L + T+ S+ L ++ +ES S + + + R+ E+ T ++ E
Sbjct: 939 KERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEES--TNYNQQLRQE 996
Query: 265 LPAIDNSY--LNQLNELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLNARVVEAETKLK 320
L + +Y L Q + + V+ +S S++T+ E+ ++ R++E E
Sbjct: 997 LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN-N 1055
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQ-KTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+ + K+ L+ Q+ +LE N+ Q +++Q++ L E T +LQV
Sbjct: 1056 ATLQAEKQALKTQLKQLE-----TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV- 1109
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+L + + Q L + S+E + E +L + +L
Sbjct: 1110 ---------ENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDH 1160
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
K+E A++Y+ + + ++ ++ E + + ++ ++ ++E ++K L+
Sbjct: 1161 EKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLK 1220
Query: 500 IE-----VKNISVRLEEVEANAIVG-GKRIISKLEARIKDMELELDEEKRRHAETIKILR 553
+E ++N + E + G R+ +K+ E+ L + + + +
Sbjct: 1221 VEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEV-LQTDHKNLKSLLNNSK 1279
Query: 554 KKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
++ +L+ + +E + + + L + +S K L E+
Sbjct: 1280 LEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEE 1323
>AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.
Length = 1715
Score = 67.3 bits (157), Expect = 2e-10
Identities = 92/506 (18%), Positives = 219/506 (43%), Gaps = 32/506 (6%)
Query: 145 RMQEIEKELDLYEKEVNLGSELR-----QKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
+++++E ++++ ++E++ E++ QK R + + EE RRN + +Y
Sbjct: 757 KIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA--DTLY 814
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMN-SCDSRVTES-ITETVRVRETSPTTC 257
+ R + R K V K +E + R +S + + V+ R +
Sbjct: 815 ----EKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 870
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
N + D N L++ KE + + N S + ++ N+ + E
Sbjct: 871 SREQNARMLQ-DGILTNHLSKQKEI--EMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIA 927
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
L+ E+ IK + Q + + L + + N DLQKTIK+ LT+ + Y+ +L
Sbjct: 928 MLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYN---GRLS 984
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
V + + ++++ E + E + ++S+T EL +
Sbjct: 985 VLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARD 1044
Query: 438 SKAKIEQELAIVAA---DYDEI-TKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
++++ ++ + D +EI +++L + + ++ E HT + L E+ + +++
Sbjct: 1045 ECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQK 1104
Query: 494 VKKSLEIEVKNISVRL--EEVEANAIVGGKRII----SKLEARIKDMELELDEEKRRHAE 547
+ ++K + + E+V+ N +G + + S+L++ + +LD+ +
Sbjct: 1105 DLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADN 1164
Query: 548 TIKILRKKERQLKEVI--IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSV 605
K + + Q ++ +Q E +++++ L + + E S+ + +RQ + +++ V
Sbjct: 1165 KEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREV 1224
Query: 606 TRVRRFQRELEAAEDRADVAESNLSL 631
VR+ Q+EL + ++E++L +
Sbjct: 1225 V-VRQLQQELADTLKKQSMSEASLEV 1249
Score = 54.4 bits (125), Expect = 1e-06
Identities = 52/271 (19%), Positives = 120/271 (44%), Gaps = 13/271 (4%)
Query: 399 EIRGNYEQALRVK-RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
E++ N+ + L VK + +E + Q ++E I L K + E+EL + ++
Sbjct: 745 ELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEE 804
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
++ R AD Y++++ +L+ E +E E ++E ++LE+E++ + L N +
Sbjct: 805 EKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNL-----NQV 859
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNI---- 573
V + + +R ++ + D H K + ++++ E++K++
Sbjct: 860 VQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKN 919
Query: 574 SLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
S+LQ+ + ++ K Q E+E + + V+ +L+ + E L+
Sbjct: 920 SMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ---NEETLTQTI 976
Query: 634 AKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
+++ ++ T + + E+ S ERL
Sbjct: 977 SQYNGRLSVLTAENAMLNSKLENEKQSKERL 1007
Score = 51.6 bits (118), Expect = 9e-06
Identities = 98/467 (20%), Positives = 194/467 (41%), Gaps = 45/467 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQ-KAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
QK + + ++ L L E+ L SE K Y+ ++ KA + ++ + ++ + + +
Sbjct: 1181 QKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQ 1240
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
+AS + +R NL E++ + ++ + E + R T C +
Sbjct: 1241 SMSEASLEVTSRYRINLED--------ETQDLKKKLGQIRNQLQEA-QDRHTEAVRCAEK 1291
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
+ ++ +K+ + + ++L +LN + + E EQL +++E + L+
Sbjct: 1292 MQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSED--EKEQLK-KLMELKQSLE 1348
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKK-QSLQLTEIQTHYDEVQRQLQVT 379
+ + KK +EL ++ N+ L+ T KK + E H D Q ++
Sbjct: 1349 CNLDQEMKK------NVELEREITGFKNL-LKMTRKKLNEYENGEFSFHGDLKTSQFEMD 1401
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
+ Q + +I LT E+E G+ L K + Q+ S V + L +K
Sbjct: 1402 I-QINKLKHKIDDLTAELETA-GSKCLHLDTKNQILQEELLSMKTVQKKCE---KLQKNK 1456
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
K+EQE+ + + + EL + Q ++ + QE K++ V L+
Sbjct: 1457 KKLEQEVINLRSHIERNMVELGQVKQYKQEIEERAR---------QEIAEKLKEVNLFLQ 1507
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+ + LE+ N K S++E RIKD+E EL + K + K +K +QL
Sbjct: 1508 AQAAS-QENLEQFRENNFASMK---SQMELRIKDLESELSKIKTSQEDFNKTELEKYKQL 1563
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
E+ K L L KT+++++ +L ++ S+ T
Sbjct: 1564 ------YLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFT 1604
Score = 48.4 bits (110), Expect = 8e-05
Identities = 84/371 (22%), Positives = 155/371 (41%), Gaps = 35/371 (9%)
Query: 270 NSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKK 329
N Y+ + ++E + Q ++ +L + + V+ + + + I +K
Sbjct: 1128 NKYIGKQESVEERLSQLQSENM-LLRQQLDDAHNKADNKEKTVINIQDQFHA----IVQK 1182
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
LQ + + L L+ NK I +K++ Q + + V RQLQ L Q
Sbjct: 1183 LQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSM 1242
Query: 390 IQSLTGEVEEIRGNYE---QALRVKRS-VEQQYEESQTRVNELTVINVNLSSSKAKIEQE 445
++ R N E Q L+ K + Q +E+Q R E + K K+E++
Sbjct: 1243 SEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKD 1302
Query: 446 LAIVAADY-------DEITKELRIA----DERYQ-RVQTELKHTVE-HLHEEQERIVKIE 492
A + +E+ K L A DE+ Q + ELK ++E +L +E ++ V++E
Sbjct: 1303 NAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELE 1362
Query: 493 AVKKSLEIEVKNISVRLEEVEAN--AIVGGKRI--------ISKLEARIKDM--ELELDE 540
+ +K +L E E + G + I+KL+ +I D+ ELE
Sbjct: 1363 REITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAG 1422
Query: 541 EKRRHAETI-KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
K H +T +IL+++ +K V +CE+ QKN L+ + + +L + +
Sbjct: 1423 SKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQ 1482
Query: 600 MSQQSVTRVRR 610
Q+ R R+
Sbjct: 1483 YKQEIEERARQ 1493
Score = 42.3 bits (95), Expect = 0.005
Identities = 73/351 (20%), Positives = 154/351 (43%), Gaps = 36/351 (10%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNI--------DLQKTI-K 356
E++ ++ E + + EV +K++L++ + LE+ L K+N+ D Q+ + +
Sbjct: 815 EKIREQLRRKEEQYRKEV-EVKQQLELSLQTLEMELRTV-KSNLNQVVQERNDAQRQLSR 872
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
+Q+ ++ + + + +Q ++ + AQ+++ S E E+ L K S+ Q
Sbjct: 873 EQNARMLQDGILTNHLSKQKEIEM-----AQKKMNSENSHSHE----EEKDLSHKNSMLQ 923
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKH 476
+ E + R+ T+ N N K K ++L IV +++ K ++ +E + ++
Sbjct: 924 E-EIAMLRLEIDTIKNQNQEKEK-KCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNG 981
Query: 477 TVEHLHEEQERI-VKIEAVKKS---LEIEVKNISVRLEEV--EANAIVGGKRIISKLEAR 530
+ L E + K+E K+S LE EV++ RL + + KR + R
Sbjct: 982 RLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQR 1041
Query: 531 IKD--------MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
+D M ++ K + + L K E +L + I+ + + LE+
Sbjct: 1042 ARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLER 1101
Query: 583 TSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIR 633
+ +S + Q+ E E Q +V ++ + E+ E+R +S L+R
Sbjct: 1102 VQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLR 1152
>M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.
Length = 2871
Score = 66.9 bits (156), Expect = 2e-10
Identities = 85/415 (20%), Positives = 184/415 (44%), Gaps = 32/415 (7%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK--QTSIEIEQLNARVVEAET 317
R+++E+ A+ L + +K+ + + I + S ++ IEIE+L + + E T
Sbjct: 1656 RLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQS-LTENLT 1714
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVA----NKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
K + + L+++ +L A N T ++L+ ++ + + E+Q +++Q
Sbjct: 1715 KEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQ 1774
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
R+ + + Q++ + ++E + Q ++ + S+ + + + L +
Sbjct: 1775 RERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLED 1834
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
L+ +K+ +E E + + R+ E+ Q++Q +L ++E I KIE+
Sbjct: 1835 ELNRAKSTLEAETRV----------KQRLECEK-QQIQNDLNQWKTQYSRKEEAIRKIES 1883
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILR 553
++ E E ++ +E ++A +R KLE ++ + +L+ E+ R+ I LR
Sbjct: 1884 EREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLR 1943
Query: 554 KKE-RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM-----SQQSVTR 607
++ +E +CE L+ D L K + +Y+ QL ++ + ++SV
Sbjct: 1944 QRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEE 2003
Query: 608 V-RRFQRELEAAEDRADVAES---NLSLIRAKHRTFVTTSTVPGSQVYLVQESRA 658
V Q L A A + S SL+ AK + ++ P S V L++ A
Sbjct: 2004 VASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKLIS----PESTVMLLEAQAA 2054
Score = 63.3 bits (147), Expect = 3e-09
Identities = 98/528 (18%), Positives = 222/528 (42%), Gaps = 54/528 (10%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTL--LEESRRNVQNE--RMYKPD 202
+E+ + YE E+N+ ++ +M + +K + L L R++++E R+
Sbjct: 1201 EEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSI 1260
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESK------------AMNSCDSRVTESITETVRVR 250
QA+ + L + +M+ K + ++R +S+ E +
Sbjct: 1261 LQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTI 1320
Query: 251 ETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQ---TSIEIEQ 307
+ + R+ E NEL + +D+ + + N + T I Q
Sbjct: 1321 QDKNKE-IERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQ 1379
Query: 308 LNARVVEAETKLKSEV---TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
L + E + ++++ TR + L +I L+ +L + +++ I++Q +E
Sbjct: 1380 LTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSE 1439
Query: 365 IQTHYDEVQRQL-QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ------ 417
+ +++ +L QVT + + R QSL + I+ ++ R+K+ ++++
Sbjct: 1440 VSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC 1499
Query: 418 YEESQTRVN--ELTVINVNLSS----SKAKI-EQELAIVAADYDEITKELRIADERYQRV 470
E+ R+ + + N S+ +K K+ EQEL + DY+ +++E + D+ R
Sbjct: 1500 LEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRF 1559
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
Q LK + +E + +++ + K + LE G +R + + +
Sbjct: 1560 QNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELE--------GMRRSLKEQAIK 1611
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
I ++ +L++ A +K ++ E L++ + + Q+ L + S +V
Sbjct: 1612 ITNLTQQLEQ-----ASIVK--KRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEAL 1664
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRT 638
+RQL +++ +Q+ R FQ+ +E + + ES + + R + T
Sbjct: 1665 RRQLLQEQESVKQAHLRNEHFQKAIE--DKSRSLNESKIEIERLQSLT 1710
Score = 59.3 bits (137), Expect = 4e-08
Identities = 83/481 (17%), Positives = 203/481 (42%), Gaps = 29/481 (6%)
Query: 154 DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRD 213
++ +++ L ELRQ M +S + + L+++ + +Q++ + + + L++++
Sbjct: 1439 EVSQRKQQLEVELRQVTQMRTEESVRY--KQSLDDAAKTIQDKNK---EIERLKQLIDKE 1493
Query: 214 YTNLS--KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV---RINTELPAI 268
+ ++ A+ + +S TE+I + ++V+E T + R++ E
Sbjct: 1494 TNDRKCLEDENARLQRVQYDLQKANSSATETINK-LKVQEQELTRLRIDYERVSQERTVK 1552
Query: 269 DNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKK 328
D N LKE Q + + + K+T+ E + + +E E + + R K
Sbjct: 1553 DQDITRFQNSLKELQLQKQKVEEEL--NRLKRTASE-DSCKRKKLEEELE---GMRRSLK 1606
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
+ I+IT L L+ A+ + +++Q L Q +L+ + +R
Sbjct: 1607 EQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRR 1666
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++ V++ E + + ES+ + L + NL+ +E+EL
Sbjct: 1667 QLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRN 1726
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVR 508
+ +YD++ + AD EL+ L R ++++ + L+ E +N+
Sbjct: 1727 LRLEYDDLRRGRSEADSDKNATILELR---SQLQISNNRTLELQGLINDLQRERENLRQE 1783
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
+E+ + A+ RI K+ ++ +E+ IK+L + + +L+ + E+
Sbjct: 1784 IEKFQKQALEASNRI-----QESKNQCTQVVQERESLLVKIKVLEQDKARLQRL----ED 1834
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESN 628
+ ++ + Q++ K+Q+ + +R R++E+ ++++ +++
Sbjct: 1835 ELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNS 1894
Query: 629 L 629
L
Sbjct: 1895 L 1895
Score = 45.6 bits (103), Expect = 6e-04
Identities = 86/418 (20%), Positives = 164/418 (39%), Gaps = 23/418 (5%)
Query: 218 SKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLN 277
+K L K + K +N +R+T I + R R++ + N Y +QL
Sbjct: 1093 AKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKS--------VEDRFDQQKNDY-DQLQ 1143
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
+ ++ K+ + K+ EIE+L + E T+ K E K++ E
Sbjct: 1144 KARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTR-KREYENELAKVRNHYNEE 1202
Query: 338 ELSLDVANKTNIDLQKT-IKKQSLQLTEIQTHY-DEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L +T I++ KT IK+ S+Q + + +++ R + D R S+
Sbjct: 1203 MSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQ 1262
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
E+ R E AL+ K + ++ Q EL + S A+ +Q L A +
Sbjct: 1263 ATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQD 1322
Query: 456 ITKEL-RIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
KE+ R+ E + + ++ E +I ++K E E+ + ++
Sbjct: 1323 KNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTM 1382
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
+ S A+I + L E R +E IK L+ Q E + + EED +
Sbjct: 1383 QK----EEDTSGYRAQIDN----LTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQK 1434
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
+ + Q++ + RQ+ + +++SV + + +D+ E LI
Sbjct: 1435 ATGSEVSQRKQQLEVELRQVTQMR--TEESVRYKQSLDDAAKTIQDKNKEIERLKQLI 1490
Score = 42.7 bits (96), Expect = 0.004
Identities = 61/309 (19%), Positives = 134/309 (43%), Gaps = 19/309 (6%)
Query: 318 KLKSEVTRIKKKL-QIQITELELSLDVAN-KTNID-LQKTIKKQSLQLTEIQTHYDEVQR 374
K ++E ++ K KL ++ + + LD + K N+D IK+ + ++T + ++ +R
Sbjct: 1064 KYQAECSQFKAKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKR 1123
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+ + D++ + L + + N K E+ +E + + L V+
Sbjct: 1124 RRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQ---KLESEKAIKEKEYEIERLRVLLQE 1180
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
+ K + E ELA V Y+E LR +Y+ K T++ + ++ E
Sbjct: 1181 EGTRKREYENELAKVRNHYNEEMSNLR---NKYETEINITKTTIKEISMQK------EDD 1231
Query: 495 KKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRK 554
K+L ++ +S +++ + I+ E R + E L ++K +E ++ +
Sbjct: 1232 SKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENAL-QQKACGSEIMQKKQH 1290
Query: 555 KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
E +LK+V+ Q ED + + SLE+ ++ + +++ + Q+ R ++ E
Sbjct: 1291 LEIELKQVMQQRSEDN---ARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENE 1347
Query: 615 LEAAEDRAD 623
L + D
Sbjct: 1348 LSKVRNNYD 1356
>J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplakin
mRNA, 3' end. ).
Length = 1752
Score = 66.9 bits (156), Expect = 2e-10
Identities = 85/415 (20%), Positives = 184/415 (44%), Gaps = 32/415 (7%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK--QTSIEIEQLNARVVEAET 317
R+++E+ A+ L + +K+ + + I + S ++ IEIE+L + + E T
Sbjct: 537 RLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQS-LTENLT 595
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVA----NKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
K + + L+++ +L A N T ++L+ ++ + + E+Q +++Q
Sbjct: 596 KEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQ 655
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
R+ + + Q++ + ++E + Q ++ + S+ + + + L +
Sbjct: 656 RERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLED 715
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
L+ +K+ +E E + + R+ E+ Q++Q +L ++E I KIE+
Sbjct: 716 ELNRAKSTLEAETRV----------KQRLECEK-QQIQNDLNQWKTQYSRKEEAIRKIES 764
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILR 553
++ E E ++ +E ++A +R KLE ++ + +L+ E+ R+ I LR
Sbjct: 765 EREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLR 824
Query: 554 KKE-RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM-----SQQSVTR 607
++ +E +CE L+ D L K + +Y+ QL ++ + ++SV
Sbjct: 825 QRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEE 884
Query: 608 V-RRFQRELEAAEDRADVAES---NLSLIRAKHRTFVTTSTVPGSQVYLVQESRA 658
V Q L A A + S SL+ AK + ++ P S V L++ A
Sbjct: 885 VASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKLIS----PESTVMLLEAQAA 935
Score = 65.3 bits (152), Expect = 7e-10
Identities = 82/412 (19%), Positives = 178/412 (43%), Gaps = 34/412 (8%)
Query: 245 ETVRVRETSPTTCVVR--INTELPAIDNSYLNQLNELKETVK----QFDDLSVYILND-- 296
E R RE VR N E+ + N Y ++N K T+K Q +D S + N
Sbjct: 62 EGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLD 121
Query: 297 ----SSKQTSIEIEQLNARVVEA-ETKLKSEVTRIKKK-LQIQITELELSLDVANKTNID 350
++ EI +LN +++A E + ++E +++K +I + + L++ K +
Sbjct: 122 RLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQ 181
Query: 351 LQKTIKKQSLQ-LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY-EQAL 408
+ + Q L E + ++++ ++ +R E+ ++R NY E+ +
Sbjct: 182 QRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEII 241
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQ 468
+K E + ++T +++LT+ + E++ + A D +T+E R E +
Sbjct: 242 SLKNQFETEINITKTTIHQLTM----------QKEEDTSGYRAQIDNLTRENRSLSEEIK 291
Query: 469 RVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLE 528
R++ L T E+L +E I + +A + + + V L +V R L+
Sbjct: 292 RLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLD 351
Query: 529 ARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
K ++ + ++E R + I + L++ + + Q ++ S +T K+
Sbjct: 352 DAAKTIQ-DKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLK 410
Query: 589 IYKRQLA----EQEGMSQQSVTR---VRRFQRELEAAEDRADVAESNLSLIR 633
+ +++L + E +SQ+ + + RFQ L+ + + E L+ ++
Sbjct: 411 VQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLK 462
Score = 63.3 bits (147), Expect = 3e-09
Identities = 98/528 (18%), Positives = 222/528 (42%), Gaps = 54/528 (10%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTL--LEESRRNVQNE--RMYKPD 202
+E+ + YE E+N+ ++ +M + +K + L L R++++E R+
Sbjct: 82 EEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSI 141
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESK------------AMNSCDSRVTESITETVRVR 250
QA+ + L + +M+ K + ++R +S+ E +
Sbjct: 142 LQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTI 201
Query: 251 ETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQ---TSIEIEQ 307
+ + R+ E NEL + +D+ + + N + T I Q
Sbjct: 202 QDKNKE-IERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQ 260
Query: 308 LNARVVEAETKLKSEV---TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
L + E + ++++ TR + L +I L+ +L + +++ I++Q +E
Sbjct: 261 LTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSE 320
Query: 365 IQTHYDEVQRQL-QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ------ 417
+ +++ +L QVT + + R QSL + I+ ++ R+K+ ++++
Sbjct: 321 VSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC 380
Query: 418 YEESQTRVN--ELTVINVNLSS----SKAKI-EQELAIVAADYDEITKELRIADERYQRV 470
E+ R+ + + N S+ +K K+ EQEL + DY+ +++E + D+ R
Sbjct: 381 LEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRF 440
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
Q LK + +E + +++ + K + LE G +R + + +
Sbjct: 441 QNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELE--------GMRRSLKEQAIK 492
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
I ++ +L++ A +K ++ E L++ + + Q+ L + S +V
Sbjct: 493 ITNLTQQLEQ-----ASIVK--KRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEAL 545
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRT 638
+RQL +++ +Q+ R FQ+ +E + + ES + + R + T
Sbjct: 546 RRQLLQEQESVKQAHLRNEHFQKAIE--DKSRSLNESKIEIERLQSLT 591
Score = 59.3 bits (137), Expect = 4e-08
Identities = 83/481 (17%), Positives = 203/481 (42%), Gaps = 29/481 (6%)
Query: 154 DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRD 213
++ +++ L ELRQ M +S + + L+++ + +Q++ + + + L++++
Sbjct: 320 EVSQRKQQLEVELRQVTQMRTEESVRY--KQSLDDAAKTIQDKNK---EIERLKQLIDKE 374
Query: 214 YTNLS--KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV---RINTELPAI 268
+ ++ A+ + +S TE+I + ++V+E T + R++ E
Sbjct: 375 TNDRKCLEDENARLQRVQYDLQKANSSATETINK-LKVQEQELTRLRIDYERVSQERTVK 433
Query: 269 DNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKK 328
D N LKE Q + + + K+T+ E + + +E E + + R K
Sbjct: 434 DQDITRFQNSLKELQLQKQKVEEEL--NRLKRTASE-DSCKRKKLEEELE---GMRRSLK 487
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
+ I+IT L L+ A+ + +++Q L Q +L+ + +R
Sbjct: 488 EQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRR 547
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++ V++ E + + ES+ + L + NL+ +E+EL
Sbjct: 548 QLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRN 607
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVR 508
+ +YD++ + AD EL+ L R ++++ + L+ E +N+
Sbjct: 608 LRLEYDDLRRGRSEADSDKNATILELR---SQLQISNNRTLELQGLINDLQRERENLRQE 664
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
+E+ + A+ RI K+ ++ +E+ IK+L + + +L+ + E+
Sbjct: 665 IEKFQKQALEASNRI-----QESKNQCTQVVQERESLLVKIKVLEQDKARLQRL----ED 715
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESN 628
+ ++ + Q++ K+Q+ + +R R++E+ ++++ +++
Sbjct: 716 ELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNS 775
Query: 629 L 629
L
Sbjct: 776 L 776
Score = 44.0 bits (99), Expect = 0.002
Identities = 71/337 (21%), Positives = 134/337 (39%), Gaps = 14/337 (4%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKT-IKK 357
K+ EIE+L + E T+ K E K++ E +L +T I++ KT IK+
Sbjct: 46 KEKEYEIERLRVLLQEEGTR-KREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKE 104
Query: 358 QSLQLTEIQTHY-DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
S+Q + + +++ R + D R S+ E+ R E AL+ K +
Sbjct: 105 ISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSE 164
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKEL-RIADERYQRVQTELK 475
++ Q EL + S A+ +Q L A + KE+ R+ E + + +
Sbjct: 165 IMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWE 224
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
+ E +I ++K E E+ + ++ + S A+I +
Sbjct: 225 YENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQK----EEDTSGYRAQIDN-- 278
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
L E R +E IK L+ Q E + + EED + + + Q++ + RQ+
Sbjct: 279 --LTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVT 336
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
+ +++SV + + +D+ E LI
Sbjct: 337 QMR--TEESVRYKQSLDDAAKTIQDKNKEIERLKQLI 371
Score = 39.5 bits (88), Expect = 0.037
Identities = 44/213 (20%), Positives = 92/213 (43%), Gaps = 13/213 (6%)
Query: 411 KRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
K E+ +E + + L V+ + K + E ELA V Y+E LR +Y+
Sbjct: 38 KLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLR---NKYETE 94
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
K T++ + ++ E K+L ++ +S +++ + I+ E R
Sbjct: 95 INITKTTIKEISMQK------EDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQR 148
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
+ E L ++K +E ++ + E +LK+V+ Q ED + + SLE+ ++ +
Sbjct: 149 RRAEENAL-QQKACGSEIMQKKQHLEIELKQVMQQRSEDN---ARHKQSLEEAAKTIQDK 204
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRAD 623
+++ + Q+ R ++ EL + D
Sbjct: 205 NKEIERLKAEFQEEAKRRWEYENELSKVRNNYD 237
>AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.
Length = 2871
Score = 66.9 bits (156), Expect = 2e-10
Identities = 85/415 (20%), Positives = 184/415 (44%), Gaps = 32/415 (7%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSK--QTSIEIEQLNARVVEAET 317
R+++E+ A+ L + +K+ + + I + S ++ IEIE+L + + E T
Sbjct: 1656 RLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQS-LTENLT 1714
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVA----NKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
K + + L+++ +L A N T ++L+ ++ + + E+Q +++Q
Sbjct: 1715 KEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQ 1774
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
R+ + + Q++ + ++E + Q ++ + S+ + + + L +
Sbjct: 1775 RERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLED 1834
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
L+ +K+ +E E + + R+ E+ Q++Q +L ++E I KIE+
Sbjct: 1835 ELNRAKSTLEAETRV----------KQRLECEK-QQIQNDLNQWKTQYSRKEEAIRKIES 1883
Query: 494 VKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILR 553
++ E E ++ +E ++A +R KLE ++ + +L+ E+ R+ I LR
Sbjct: 1884 EREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDKLR 1943
Query: 554 KKE-RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM-----SQQSVTR 607
++ +E +CE L+ D L K + +Y+ QL ++ + ++SV
Sbjct: 1944 QRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKTTLDKLLKGKKSVEE 2003
Query: 608 V-RRFQRELEAAEDRADVAES---NLSLIRAKHRTFVTTSTVPGSQVYLVQESRA 658
V Q L A A + S SL+ AK + ++ P S V L++ A
Sbjct: 2004 VASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKLIS----PESTVMLLEAQAA 2054
Score = 63.3 bits (147), Expect = 3e-09
Identities = 98/528 (18%), Positives = 222/528 (42%), Gaps = 54/528 (10%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTL--LEESRRNVQNE--RMYKPD 202
+E+ + YE E+N+ ++ +M + +K + L L R++++E R+
Sbjct: 1201 EEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSI 1260
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESK------------AMNSCDSRVTESITETVRVR 250
QA+ + L + +M+ K + ++R +S+ E +
Sbjct: 1261 LQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTI 1320
Query: 251 ETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQ---TSIEIEQ 307
+ + R+ E NEL + +D+ + + N + T I Q
Sbjct: 1321 QDKNKE-IERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQ 1379
Query: 308 LNARVVEAETKLKSEV---TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTE 364
L + E + ++++ TR + L +I L+ +L + +++ I++Q +E
Sbjct: 1380 LTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSE 1439
Query: 365 IQTHYDEVQRQL-QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ------ 417
+ +++ +L QVT + + R QSL + I+ ++ R+K+ ++++
Sbjct: 1440 VSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC 1499
Query: 418 YEESQTRVN--ELTVINVNLSS----SKAKI-EQELAIVAADYDEITKELRIADERYQRV 470
E+ R+ + + N S+ +K K+ EQEL + DY+ +++E + D+ R
Sbjct: 1500 LEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRF 1559
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
Q LK + +E + +++ + K + LE G +R + + +
Sbjct: 1560 QNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELE--------GMRRSLKEQAIK 1611
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
I ++ +L++ A +K ++ E L++ + + Q+ L + S +V
Sbjct: 1612 ITNLTQQLEQ-----ASIVK--KRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEAL 1664
Query: 591 KRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRT 638
+RQL +++ +Q+ R FQ+ +E + + ES + + R + T
Sbjct: 1665 RRQLLQEQESVKQAHLRNEHFQKAIE--DKSRSLNESKIEIERLQSLT 1710
Score = 59.3 bits (137), Expect = 4e-08
Identities = 83/481 (17%), Positives = 203/481 (42%), Gaps = 29/481 (6%)
Query: 154 DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRD 213
++ +++ L ELRQ M +S + + L+++ + +Q++ + + + L++++
Sbjct: 1439 EVSQRKQQLEVELRQVTQMRTEESVRY--KQSLDDAAKTIQDKNK---EIERLKQLIDKE 1493
Query: 214 YTNLS--KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV---RINTELPAI 268
+ ++ A+ + +S TE+I + ++V+E T + R++ E
Sbjct: 1494 TNDRKCLEDENARLQRVQYDLQKANSSATETINK-LKVQEQELTRLRIDYERVSQERTVK 1552
Query: 269 DNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKK 328
D N LKE Q + + + K+T+ E + + +E E + + R K
Sbjct: 1553 DQDITRFQNSLKELQLQKQKVEEEL--NRLKRTASE-DSCKRKKLEEELE---GMRRSLK 1606
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
+ I+IT L L+ A+ + +++Q L Q +L+ + +R
Sbjct: 1607 EQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRR 1666
Query: 389 RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAI 448
++ V++ E + + ES+ + L + NL+ +E+EL
Sbjct: 1667 QLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRN 1726
Query: 449 VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVR 508
+ +YD++ + AD EL+ L R ++++ + L+ E +N+
Sbjct: 1727 LRLEYDDLRRGRSEADSDKNATILELR---SQLQISNNRTLELQGLINDLQRERENLRQE 1783
Query: 509 LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEE 568
+E+ + A+ RI K+ ++ +E+ IK+L + + +L+ + E+
Sbjct: 1784 IEKFQKQALEASNRI-----QESKNQCTQVVQERESLLVKIKVLEQDKARLQRL----ED 1834
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESN 628
+ ++ + Q++ K+Q+ + +R R++E+ ++++ +++
Sbjct: 1835 ELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNS 1894
Query: 629 L 629
L
Sbjct: 1895 L 1895
Score = 45.6 bits (103), Expect = 6e-04
Identities = 86/418 (20%), Positives = 164/418 (39%), Gaps = 23/418 (5%)
Query: 218 SKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLN 277
+K L K + K +N +R+T I + R R++ + N Y +QL
Sbjct: 1093 AKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKS--------VEDRFDQQKNDY-DQLQ 1143
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
+ ++ K+ + K+ EIE+L + E T+ K E K++ E
Sbjct: 1144 KARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTR-KREYENELAKVRNHYNEE 1202
Query: 338 ELSLDVANKTNIDLQKT-IKKQSLQLTEIQTHY-DEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L +T I++ KT IK+ S+Q + + +++ R + D R S+
Sbjct: 1203 MSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQ 1262
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
E+ R E AL+ K + ++ Q EL + S A+ +Q L A +
Sbjct: 1263 ATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQD 1322
Query: 456 ITKEL-RIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
KE+ R+ E + + ++ E +I ++K E E+ + ++
Sbjct: 1323 KNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTM 1382
Query: 515 NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
+ S A+I + L E R +E IK L+ Q E + + EED +
Sbjct: 1383 QK----EEDTSGYRAQIDN----LTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQK 1434
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
+ + Q++ + RQ+ + +++SV + + +D+ E LI
Sbjct: 1435 ATGSEVSQRKQQLEVELRQVTQMR--TEESVRYKQSLDDAAKTIQDKNKEIERLKQLI 1490
Score = 42.7 bits (96), Expect = 0.004
Identities = 61/309 (19%), Positives = 134/309 (43%), Gaps = 19/309 (6%)
Query: 318 KLKSEVTRIKKKL-QIQITELELSLDVAN-KTNID-LQKTIKKQSLQLTEIQTHYDEVQR 374
K ++E ++ K KL ++ + + LD + K N+D IK+ + ++T + ++ +R
Sbjct: 1064 KYQAECSQFKAKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKR 1123
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+ + D++ + L + + N K E+ +E + + L V+
Sbjct: 1124 RRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQ---KLESEKAIKEKEYEIERLRVLLQE 1180
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
+ K + E ELA V Y+E LR +Y+ K T++ + ++ E
Sbjct: 1181 EGTRKREYENELAKVRNHYNEEMSNLR---NKYETEINITKTTIKEISMQK------EDD 1231
Query: 495 KKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRK 554
K+L ++ +S +++ + I+ E R + E L ++K +E ++ +
Sbjct: 1232 SKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENAL-QQKACGSEIMQKKQH 1290
Query: 555 KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
E +LK+V+ Q ED + + SLE+ ++ + +++ + Q+ R ++ E
Sbjct: 1291 LEIELKQVMQQRSEDN---ARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENE 1347
Query: 615 LEAAEDRAD 623
L + D
Sbjct: 1348 LSKVRNNYD 1356
>Y09631-1|CAA70844.1| 758|Homo sapiens PIBF1 protein protein.
Length = 758
Score = 66.5 bits (155), Expect = 3e-10
Identities = 88/366 (24%), Positives = 171/366 (46%), Gaps = 36/366 (9%)
Query: 217 LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQL 276
+ KN+LA+ L +K N ++TE+ E + C R+ EL D L Q
Sbjct: 203 VKKNILAEELSTNK--NQL-KQLTETYEEDRKNYSEVQIRCQ-RLALELA--DTKQLIQQ 256
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA----ETKLKSEVTRIKKKLQI 332
+ ++ + +D V D+ +Q IE+ + + ++EA +TK +SE+++ L+
Sbjct: 257 GDYRQ--ENYD--KVKSERDALEQEVIELRRKH-EILEASHMIQTKERSELSKEVVTLEQ 311
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+T L+ + N+ N++L + +L +Q +E ++ + ++Y ++ ++
Sbjct: 312 TVTLLQKDKEYLNRQNMELSVCCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKT 371
Query: 393 -----LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA 447
L E+E+IR Q + R+ ++ E + R N+ + A E+E A
Sbjct: 372 EYENKLHDELEQIRLKTNQEIDQLRNASREMYERENR-------NLREARDNAVAEKERA 424
Query: 448 IVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI 505
++ A+ D + K ++ D RY+ +Q TE K T E LH+ + + + E V+ E +N+
Sbjct: 425 VM-AEKDALEKHDQLLD-RYRELQLSTESKVT-EFLHQSKLKSFESERVQLLQEETARNL 481
Query: 506 S---VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + E+ + V K S L+A + EL + H + I K E++L E+
Sbjct: 482 TQCQLECEKYQKKLEVLTKEFYS-LQASSEKRITELQAQNSEHQARLDIYEKLEKELDEI 540
Query: 563 IIQCEE 568
I+Q E
Sbjct: 541 IMQTAE 546
Score = 31.9 bits (69), Expect = 7.5
Identities = 71/345 (20%), Positives = 155/345 (44%), Gaps = 39/345 (11%)
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+S+ I L+ + LE ++ + ++ + ++ + + QL E + +Q L++
Sbjct: 8 ESKKVNISSSLESEDISLETTVPTDDISSSEEREGKVRITRQLIERKELLHNIQL-LKIE 66
Query: 380 LDQYG--VAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
L Q + ++ LT ++EE+ AL K+ + + + N+L + S
Sbjct: 67 LSQKTMMIDNLKVDYLT-KIEELEEKLNDALHQKQLLTLRLD------NQLAFQQKDASK 119
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+ ++QE+ + K+L + + + +++ ++ +E+ +K++A +
Sbjct: 120 YQELMKQEMETILLRQ----KQLEETNLQLREKAGDVRRSLRDFELTEEQYIKLKAFPED 175
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
+ +SVR E +++ L I EL +K AE L +
Sbjct: 176 QLSIPEYVSVRFYE-----------LVNPLRKEI----CELQVKKNILAEE---LSTNKN 217
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR--RFQREL 615
QLK++ EED+KN S +Q ++ + +++ K QL +Q Q++ +V+ R E
Sbjct: 218 QLKQLTETYEEDRKNYSEVQIRCQRLALELADTK-QLIQQGDYRQENYDKVKSERDALEQ 276
Query: 616 EAAEDRA--DVAESNLSLIRAKHRTFVTTSTVPGSQ-VYLVQESR 657
E E R ++ E++ +I+ K R+ ++ V Q V L+Q+ +
Sbjct: 277 EVIELRRKHEILEAS-HMIQTKERSELSKEVVTLEQTVTLLQKDK 320
>BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 66.5 bits (155), Expect = 3e-10
Identities = 89/414 (21%), Positives = 191/414 (46%), Gaps = 42/414 (10%)
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
+ K T K+ D L++ +++ S+ E++ E + KLK E+ ++K L+ + +
Sbjct: 997 KFKATEKELKDQ----LSEQTQKYSVSEEEVKKNKQEND-KLKKEIFTLQKDLRDKTVLI 1051
Query: 338 ELSLDV----ANKTNIDLQKTIKKQSLQLTEIQTH----YDEVQRQLQVTLDQYGVAQRR 389
E S ++ + KT+ +L K +K S + TE++ +E +Q L + Q++
Sbjct: 1052 EKSHEMERALSRKTD-ELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQ 1110
Query: 390 ---IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS-------- 438
++ + + + G E +S+++ YE+ Q V +L + N +S
Sbjct: 1111 HVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHL 1170
Query: 439 --KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV----KIE 492
K E+E+ I+ A E +E + E ++Q+E+++T + L + + R V K +
Sbjct: 1171 QIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYK 1230
Query: 493 AVKKSLEIEVKNISVRL-------EEVEANAIVGGKRIIS-KLEARIK--DMELELDEEK 542
A K LE ++ +++ +L EEV + K+ IS K E + +E E+ ++K
Sbjct: 1231 ATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQK 1290
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
R +++ + + +R+++E Q E I+ L + +E+ Q ++ + ++
Sbjct: 1291 ERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTK 1350
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES 656
+ + Q ++++ E + A+ + A +RT + S G VQE+
Sbjct: 1351 RQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHL-LSAAQGHMDEDVQEA 1403
Score = 50.4 bits (115), Expect = 2e-05
Identities = 61/304 (20%), Positives = 139/304 (45%), Gaps = 27/304 (8%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S+KQ ++++ A V L E R+K+ QI +LE +L D+QK +
Sbjct: 454 ESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALK-------DVQKRM 506
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ ++ ++QTH+ ++ L T + R + L ++++++ YE A +
Sbjct: 507 YESEGKVKQMQTHFLALKEHL--TSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLR 564
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q ++++ V E L ++++EL++ + ++ +++ + + + + +L
Sbjct: 565 NQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLA 624
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
++ K E +K SL EV + +L E+E R K + I+ ++
Sbjct: 625 LSIP--------AEKFENMKSSLSNEVNEKAKKLVEME--------REHEKSLSEIRQLK 668
Query: 536 LELDEEKRRHAETIKILRKKE--RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
EL+ K + A+ +K ++ +L++ + + ++L +L+K +KV + +
Sbjct: 669 RELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKL 728
Query: 594 LAEQ 597
L EQ
Sbjct: 729 LKEQ 732
Score = 42.7 bits (96), Expect = 0.004
Identities = 72/354 (20%), Positives = 168/354 (47%), Gaps = 39/354 (11%)
Query: 277 NELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLN---ARVVEAETKLKSEVTRI---KK 328
++LK+ +++ S + L + KQ + +E+ +++E +L+ E++ ++
Sbjct: 544 DQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMERE 603
Query: 329 KLQIQITELE-----LSLDVANKTNIDLQKTIKKQ-SLQLTEIQTHYDEVQRQLQVTLDQ 382
K ++TE+E LS +A + + +K S ++ E E++R+ + +L +
Sbjct: 604 KKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSE 663
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+R ++++ ++ + E+ +VK +EQ+ E ++ ELT+ N L K+
Sbjct: 664 IRQLKRELENVKAKLAQ-HVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKV 722
Query: 443 EQELAIVAADYDEITKELRIADERY--QRVQTELKHTVEHLHEEQER---IVKIEAVKKS 497
+ ++ +T E++ Y +V ++K + + + ++ R V + +K
Sbjct: 723 YLDNKLLKEQAHNLTIEMK---NHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKK 779
Query: 498 LEIE---VKNISV-----RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR---HA 546
LE+E ++N S+ RLE V K II+ L++ I +++ +L E K++
Sbjct: 780 LEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIA-LKSNIVELKKQLSELKKKCGEDQ 838
Query: 547 ETIKILRKKERQLKEVI----IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
E I L + LK+++ + + ++ L D+L KT++++ K++ +
Sbjct: 839 EKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFED 892
Score = 39.9 bits (89), Expect = 0.028
Identities = 55/248 (22%), Positives = 113/248 (45%), Gaps = 16/248 (6%)
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI---KKQSLQLTEIQTHYDEVQRQLQ 377
SE +KK+L+ T E + K +L + K +L+ ++ DE +QL+
Sbjct: 437 SENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLE 496
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
L Q+R+ G+V++++ ++ L +K + + R+ E + L
Sbjct: 497 DALKD---VQKRMYESEGKVKQMQTHF---LALKEHLTSEAASGNHRLTE--ELKDQLKD 548
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
K K E A V ++I + I +E ++R + +L + L +E + ++E KK
Sbjct: 549 LKVKYEGASAEVGKLRNQIKQNEMIVEE-FKRDEGKLIEENKRLQKELS-MCEMEREKKG 606
Query: 498 LEI-EVKNISVRLEEVEANAIVGGK--RIISKLEARIKDMELELDEEKRRHAETIKILRK 554
++ E++ + L A +I K + S L + + +L E +R H +++ +R+
Sbjct: 607 RKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQ 666
Query: 555 KERQLKEV 562
+R+L+ V
Sbjct: 667 LKRELENV 674
Score = 39.9 bits (89), Expect = 0.028
Identities = 82/381 (21%), Positives = 165/381 (43%), Gaps = 41/381 (10%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYR-----GKSAKAIAQTLLEESRRNVQNER 197
KK + ++K DL +K V + + A+ R K K ++Q E +NV+ +
Sbjct: 1034 KKEIFTLQK--DLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEV--KNVKEKL 1089
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
+ + Q S L ++ L + K++N + E + R E T
Sbjct: 1090 VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQT- 1148
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
V +++ L NS + L+ +K+ + V I+ S + E E+ + +E +
Sbjct: 1149 VTKLHQLLENQKNSSVPLAEHLQ--IKEAFEKEVGIIKASLR----EKEEESQNKMEEVS 1202
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL+SEV K+ L+ T + L T DL+ I + +L + Y+EV ++
Sbjct: 1203 KLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV- 1261
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE-LTVINVNLS 436
L + +EI E+ L + S+EQ+ ++ + R ++ LT I +
Sbjct: 1262 ---------------LHAKKKEISAKDEKEL-LHFSIEQEIKDQKERCDKSLTTI----T 1301
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIV-KIEA 493
+ +I++ + A ++IT+ L + Q + ++L +T + + Q +++ ++
Sbjct: 1302 ELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQH 1361
Query: 494 VKKSLEIEVKNISVRLEEVEA 514
KSLE ++ + + +EV A
Sbjct: 1362 QVKSLEQQLADADRQHQEVIA 1382
>BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 66.5 bits (155), Expect = 3e-10
Identities = 89/414 (21%), Positives = 191/414 (46%), Gaps = 42/414 (10%)
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
+ K T K+ D L++ +++ S+ E++ E + KLK E+ ++K L+ + +
Sbjct: 997 KFKATEKELKDQ----LSEQTQKYSVSEEEVKKNKQEND-KLKKEIFTLQKDLRDKTVLI 1051
Query: 338 ELSLDV----ANKTNIDLQKTIKKQSLQLTEIQTH----YDEVQRQLQVTLDQYGVAQRR 389
E S ++ + KT+ +L K +K S + TE++ +E +Q L + Q++
Sbjct: 1052 EKSHEMERALSRKTD-ELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQ 1110
Query: 390 ---IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS-------- 438
++ + + + G E +S+++ YE+ Q V +L + N +S
Sbjct: 1111 HVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHL 1170
Query: 439 --KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV----KIE 492
K E+E+ I+ A E +E + E ++Q+E+++T + L + + R V K +
Sbjct: 1171 QIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYK 1230
Query: 493 AVKKSLEIEVKNISVRL-------EEVEANAIVGGKRIIS-KLEARIK--DMELELDEEK 542
A K LE ++ +++ +L EEV + K+ IS K E + +E E+ ++K
Sbjct: 1231 ATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQK 1290
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
R +++ + + +R+++E Q E I+ L + +E+ Q ++ + ++
Sbjct: 1291 ERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTK 1350
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES 656
+ + Q ++++ E + A+ + A +RT + S G VQE+
Sbjct: 1351 RQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHL-LSAAQGHMDEDVQEA 1403
Score = 50.4 bits (115), Expect = 2e-05
Identities = 61/304 (20%), Positives = 139/304 (45%), Gaps = 27/304 (8%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S+KQ ++++ A V L E R+K+ QI +LE +L D+QK +
Sbjct: 454 ESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALK-------DVQKRM 506
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ ++ ++QTH+ ++ L T + R + L ++++++ YE A +
Sbjct: 507 YESEGKVKQMQTHFLALKEHL--TSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLR 564
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q ++++ V E L ++++EL++ + ++ +++ + + + + +L
Sbjct: 565 NQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLA 624
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
++ K E +K SL EV + +L E+E R K + I+ ++
Sbjct: 625 LSIP--------AEKFENMKSSLSNEVNEKAKKLVEME--------REHEKSLSEIRQLK 668
Query: 536 LELDEEKRRHAETIKILRKKE--RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
EL+ K + A+ +K ++ +L++ + + ++L +L+K +KV + +
Sbjct: 669 RELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKL 728
Query: 594 LAEQ 597
L EQ
Sbjct: 729 LKEQ 732
Score = 42.7 bits (96), Expect = 0.004
Identities = 72/354 (20%), Positives = 168/354 (47%), Gaps = 39/354 (11%)
Query: 277 NELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLN---ARVVEAETKLKSEVTRI---KK 328
++LK+ +++ S + L + KQ + +E+ +++E +L+ E++ ++
Sbjct: 544 DQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMERE 603
Query: 329 KLQIQITELE-----LSLDVANKTNIDLQKTIKKQ-SLQLTEIQTHYDEVQRQLQVTLDQ 382
K ++TE+E LS +A + + +K S ++ E E++R+ + +L +
Sbjct: 604 KKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSE 663
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+R ++++ ++ + E+ +VK +EQ+ E ++ ELT+ N L K+
Sbjct: 664 IRQLKRELENVKAKLAQ-HVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKV 722
Query: 443 EQELAIVAADYDEITKELRIADERY--QRVQTELKHTVEHLHEEQER---IVKIEAVKKS 497
+ ++ +T E++ Y +V ++K + + + ++ R V + +K
Sbjct: 723 YLDNKLLKEQAHNLTIEMK---NHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKK 779
Query: 498 LEIE---VKNISV-----RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR---HA 546
LE+E ++N S+ RLE V K II+ L++ I +++ +L E K++
Sbjct: 780 LEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIA-LKSNIVELKKQLSELKKKCGEDQ 838
Query: 547 ETIKILRKKERQLKEVI----IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
E I L + LK+++ + + ++ L D+L KT++++ K++ +
Sbjct: 839 EKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFED 892
Score = 39.9 bits (89), Expect = 0.028
Identities = 55/248 (22%), Positives = 113/248 (45%), Gaps = 16/248 (6%)
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI---KKQSLQLTEIQTHYDEVQRQLQ 377
SE +KK+L+ T E + K +L + K +L+ ++ DE +QL+
Sbjct: 437 SENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLE 496
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
L Q+R+ G+V++++ ++ L +K + + R+ E + L
Sbjct: 497 DALKD---VQKRMYESEGKVKQMQTHF---LALKEHLTSEAASGNHRLTE--ELKDQLKD 548
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
K K E A V ++I + I +E ++R + +L + L +E + ++E KK
Sbjct: 549 LKVKYEGASAEVGKLRNQIKQNEMIVEE-FKRDEGKLIEENKRLQKELS-MCEMEREKKG 606
Query: 498 LEI-EVKNISVRLEEVEANAIVGGK--RIISKLEARIKDMELELDEEKRRHAETIKILRK 554
++ E++ + L A +I K + S L + + +L E +R H +++ +R+
Sbjct: 607 RKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQ 666
Query: 555 KERQLKEV 562
+R+L+ V
Sbjct: 667 LKRELENV 674
Score = 39.9 bits (89), Expect = 0.028
Identities = 82/381 (21%), Positives = 165/381 (43%), Gaps = 41/381 (10%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYR-----GKSAKAIAQTLLEESRRNVQNER 197
KK + ++K DL +K V + + A+ R K K ++Q E +NV+ +
Sbjct: 1034 KKEIFTLQK--DLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEV--KNVKEKL 1089
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
+ + Q S L ++ L + K++N + E + R E T
Sbjct: 1090 VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQT- 1148
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
V +++ L NS + L+ +K+ + V I+ S + E E+ + +E +
Sbjct: 1149 VTKLHQLLENQKNSSVPLAEHLQ--IKEAFEKEVGIIKASLR----EKEEESQNKMEEVS 1202
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL+SEV K+ L+ T + L T DL+ I + +L + Y+EV ++
Sbjct: 1203 KLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV- 1261
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE-LTVINVNLS 436
L + +EI E+ L + S+EQ+ ++ + R ++ LT I +
Sbjct: 1262 ---------------LHAKKKEISAKDEKEL-LHFSIEQEIKDQKERCDKSLTTI----T 1301
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIV-KIEA 493
+ +I++ + A ++IT+ L + Q + ++L +T + + Q +++ ++
Sbjct: 1302 ELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQH 1361
Query: 494 VKKSLEIEVKNISVRLEEVEA 514
KSLE ++ + + +EV A
Sbjct: 1362 QVKSLEQQLADADRQHQEVIA 1382
>BC051911-1|AAH51911.1| 757|Homo sapiens chromosome 13 open reading
frame 24 protein.
Length = 757
Score = 66.5 bits (155), Expect = 3e-10
Identities = 88/366 (24%), Positives = 171/366 (46%), Gaps = 36/366 (9%)
Query: 217 LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQL 276
+ KN+LA+ L +K N ++TE+ E + C R+ EL D L Q
Sbjct: 203 VKKNILAEELSTNK--NQL-KQLTETYEEDRKNYSEVQIRCQ-RLALELA--DTKQLIQQ 256
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA----ETKLKSEVTRIKKKLQI 332
+ ++ + +D V D+ +Q IE+ + + ++EA +TK +SE+++ L+
Sbjct: 257 GDYRQ--ENYD--KVKSERDALEQEVIELRRKH-EILEASHMIQTKERSELSKEVVTLEQ 311
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+T L+ + N+ N++L + +L +Q +E ++ + ++Y ++ ++
Sbjct: 312 TVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKT 371
Query: 393 -----LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA 447
L E+E+IR Q + R+ ++ E + R N+ + A E+E A
Sbjct: 372 EYENKLHDELEQIRLKTNQEIDQLRNASREMYERENR-------NLREARDNAVAEKERA 424
Query: 448 IVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI 505
++ A+ D + K ++ D RY+ +Q TE K T E LH+ + + + E V+ E +N+
Sbjct: 425 VM-AEKDALEKHDQLLD-RYRELQLSTESKVT-EFLHQSKLKSFESERVQLLQEETARNL 481
Query: 506 S---VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + E+ + V K S L+A + EL + H + I K E++L E+
Sbjct: 482 TQCQLECEKYQKKLEVLTKEFYS-LQASSEKRITELQAQNSEHQARLDIYEKLEKELDEI 540
Query: 563 IIQCEE 568
I+Q E
Sbjct: 541 IMQTAE 546
Score = 32.7 bits (71), Expect = 4.3
Identities = 64/375 (17%), Positives = 158/375 (42%), Gaps = 26/375 (6%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI---EIEQLNAR---VVEAE 316
T++ ++ + L++ + + D+ + D+SK + E+E + R + E
Sbjct: 83 TKIEELEEKLNDALHQKQLLTLRLDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETN 142
Query: 317 TKLKSEVTRIKKKLQ-IQITELE-LSLDVANKTNIDLQKTIKKQSLQLTE-IQTHYDEVQ 373
+L+ + +++ L+ ++TE + + L + + + + + + +L ++ E+Q
Sbjct: 143 LQLREKAGDVRRNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVRFYELVNPLRKEICELQ 202
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY-EQALRVKR-SVEQQYEESQTRVNELTVI 431
+ + ++ + +++ LT EE R NY E +R +R ++E + + +
Sbjct: 203 VKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQE 262
Query: 432 NVN-LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE---LKHTVEHLHEEQER 487
N + + S + +EQE+ + ++ + I + + E L+ TV L +++E
Sbjct: 263 NYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKE- 321
Query: 488 IVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK---RIISKLEARIKDMELELDEEKRR 544
+ L + + RLE ++A K + K A + E + +
Sbjct: 322 --YLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKLHD 379
Query: 545 HAETIKILRKKE-RQLKEVIIQC-EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
E I++ +E QL+ + E + +N+ +D+ ++ + ++ E+
Sbjct: 380 ELEQIRLKTNQEIDQLRNASREMYERENRNLREARDNAVAEKERAVMAEKDALEKH---D 436
Query: 603 QSVTRVRRFQRELEA 617
Q + R R Q E+
Sbjct: 437 QLLDRYRELQLSTES 451
Score = 31.5 bits (68), Expect = 9.9
Identities = 31/111 (27%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-- 609
L + QLK++ EED+KN S +Q ++ + +++ K QL +Q Q++ +V+
Sbjct: 212 LSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTK-QLIQQGDYRQENYDKVKSE 270
Query: 610 RFQRELEAAEDRA--DVAESNLSLIRAKHRTFVTTSTVPGSQ-VYLVQESR 657
R E E E R ++ E++ +I+ K R+ ++ V Q V L+Q+ +
Sbjct: 271 RDALEQEVIELRRKHEILEAS-HMIQTKERSELSKEVVTLEQTVTLLQKDK 320
>BC041806-1|AAH41806.1| 698|Homo sapiens C13orf24 protein protein.
Length = 698
Score = 66.5 bits (155), Expect = 3e-10
Identities = 88/366 (24%), Positives = 171/366 (46%), Gaps = 36/366 (9%)
Query: 217 LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQL 276
+ KN+LA+ L +K N ++TE+ E + C R+ EL D L Q
Sbjct: 203 VKKNILAEELSTNK--NQL-KQLTETYEEDRKNYSEVQIRCQ-RLALELA--DTKQLIQQ 256
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA----ETKLKSEVTRIKKKLQI 332
+ ++ + +D V D+ +Q IE+ + + ++EA +TK +SE+++ L+
Sbjct: 257 GDYRQ--ENYD--KVKSERDALEQEVIELRRKH-EILEASHMIQTKERSELSKEVVTLEQ 311
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+T L+ + N+ N++L + +L +Q +E ++ + ++Y ++ ++
Sbjct: 312 TVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKT 371
Query: 393 -----LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA 447
L E+E+IR Q + R+ ++ E + R N+ + A E+E A
Sbjct: 372 EYENKLHDELEQIRLKTNQEIDQLRNASREMYERENR-------NLREARDNAVAEKERA 424
Query: 448 IVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI 505
++ A+ D + K ++ D RY+ +Q TE K T E LH+ + + + E V+ E +N+
Sbjct: 425 VM-AEKDALEKHDQLLD-RYRELQLSTESKVT-EFLHQSKLKSFESERVQLLQEETARNL 481
Query: 506 S---VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + E+ + V K S L+A + EL + H + I K E++L E+
Sbjct: 482 TQCQLECEKYQEKLEVLTKEFYS-LQASSEKRITELQAQNSEHQARLDIYEKLEKELDEI 540
Query: 563 IIQCEE 568
I+Q E
Sbjct: 541 IMQTAE 546
Score = 31.9 bits (69), Expect = 7.5
Identities = 72/345 (20%), Positives = 154/345 (44%), Gaps = 39/345 (11%)
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
+S+ I L+ + LE ++ + ++ + ++ + + QL E + +Q L++
Sbjct: 8 ESKKVNISSSLESEDISLETTVPTDDISSSEEREGKVRITRQLIERKELLHNIQL-LKIE 66
Query: 380 LDQYG--VAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
L Q + ++ LT ++EE+ AL K+ + + + N+L + S
Sbjct: 67 LSQKTMMIDNLKVDYLT-KIEELEEKLNDALHQKQLLTLRLD------NQLAFQQKDASK 119
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+ ++QE+ + K+L + + + +++ + +E+ VK++A +
Sbjct: 120 YQELMKQEMETILLRQ----KQLEETNLQLREKAGDVRRNLRDFELTEEQYVKLKAFPED 175
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
+ +SVR E +++ L I EL +K AE L +
Sbjct: 176 QLSIPEYVSVRFYE-----------LVNPLRKEI----CELQVKKNILAEE---LSTNKN 217
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR--RFQREL 615
QLK++ EED+KN S +Q ++ + +++ K QL +Q Q++ +V+ R E
Sbjct: 218 QLKQLTETYEEDRKNYSEVQIRCQRLALELADTK-QLIQQGDYRQENYDKVKSERDALEQ 276
Query: 616 EAAEDRA--DVAESNLSLIRAKHRTFVTTSTVPGSQ-VYLVQESR 657
E E R ++ E++ +I+ K R+ ++ V Q V L+Q+ +
Sbjct: 277 EVIELRRKHEILEAS-HMIQTKERSELSKEVVTLEQTVTLLQKDK 320
>AL391384-3|CAI15673.1| 757|Homo sapiens RP11-505F3.1 protein.
Length = 757
Score = 66.5 bits (155), Expect = 3e-10
Identities = 88/366 (24%), Positives = 171/366 (46%), Gaps = 36/366 (9%)
Query: 217 LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQL 276
+ KN+LA+ L +K N ++TE+ E + C R+ EL D L Q
Sbjct: 203 VKKNILAEELSTNK--NQL-KQLTETYEEDRKNYSEVQIRCQ-RLALELA--DTKQLIQQ 256
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA----ETKLKSEVTRIKKKLQI 332
+ ++ + +D V D+ +Q IE+ + + ++EA +TK +SE+++ L+
Sbjct: 257 GDYRQ--ENYD--KVKSERDALEQEVIELRRKH-EILEASHMIQTKERSELSKEVVTLEQ 311
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+T L+ + N+ N++L + +L +Q +E ++ + ++Y ++ ++
Sbjct: 312 TVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKT 371
Query: 393 -----LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA 447
L E+E+IR Q + R+ ++ E + R N+ + A E+E A
Sbjct: 372 EYENKLHDELEQIRLKTNQEIDQLRNASREMYERENR-------NLREARDNAVAEKERA 424
Query: 448 IVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI 505
++ A+ D + K ++ D RY+ +Q TE K T E LH+ + + + E V+ E +N+
Sbjct: 425 VM-AEKDALEKHDQLLD-RYRELQLSTESKVT-EFLHQSKLKSFESERVQLLQEETARNL 481
Query: 506 S---VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + E+ + V K S L+A + EL + H + I K E++L E+
Sbjct: 482 TQCQLECEKYQKKLEVLTKEFYS-LQASSEKRITELQAQNSEHQARLDIYEKLEKELDEI 540
Query: 563 IIQCEE 568
I+Q E
Sbjct: 541 IMQTAE 546
Score = 32.7 bits (71), Expect = 4.3
Identities = 64/375 (17%), Positives = 158/375 (42%), Gaps = 26/375 (6%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI---EIEQLNAR---VVEAE 316
T++ ++ + L++ + + D+ + D+SK + E+E + R + E
Sbjct: 83 TKIEELEEKLNDALHQKQLLTLRLDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETN 142
Query: 317 TKLKSEVTRIKKKLQ-IQITELE-LSLDVANKTNIDLQKTIKKQSLQLTE-IQTHYDEVQ 373
+L+ + +++ L+ ++TE + + L + + + + + + +L ++ E+Q
Sbjct: 143 LQLREKAGDVRRNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVRFYELVNPLRKEICELQ 202
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY-EQALRVKR-SVEQQYEESQTRVNELTVI 431
+ + ++ + +++ LT EE R NY E +R +R ++E + + +
Sbjct: 203 VKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQE 262
Query: 432 NVN-LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE---LKHTVEHLHEEQER 487
N + + S + +EQE+ + ++ + I + + E L+ TV L +++E
Sbjct: 263 NYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKE- 321
Query: 488 IVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK---RIISKLEARIKDMELELDEEKRR 544
+ L + + RLE ++A K + K A + E + +
Sbjct: 322 --YLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKLHD 379
Query: 545 HAETIKILRKKE-RQLKEVIIQC-EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
E I++ +E QL+ + E + +N+ +D+ ++ + ++ E+
Sbjct: 380 ELEQIRLKTNQEIDQLRNASREMYERENRNLREARDNAVAEKERAVMAEKDALEKH---D 436
Query: 603 QSVTRVRRFQRELEA 617
Q + R R Q E+
Sbjct: 437 QLLDRYRELQLSTES 451
Score = 31.5 bits (68), Expect = 9.9
Identities = 31/111 (27%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-- 609
L + QLK++ EED+KN S +Q ++ + +++ K QL +Q Q++ +V+
Sbjct: 212 LSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTK-QLIQQGDYRQENYDKVKSE 270
Query: 610 RFQRELEAAEDRA--DVAESNLSLIRAKHRTFVTTSTVPGSQ-VYLVQESR 657
R E E E R ++ E++ +I+ K R+ ++ V Q V L+Q+ +
Sbjct: 271 RDALEQEVIELRRKHEILEAS-HMIQTKERSELSKEVVTLEQTVTLLQKDK 320
>AL354720-1|CAI14869.1| 757|Homo sapiens RP11-505F3.1 protein.
Length = 757
Score = 66.5 bits (155), Expect = 3e-10
Identities = 88/366 (24%), Positives = 171/366 (46%), Gaps = 36/366 (9%)
Query: 217 LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQL 276
+ KN+LA+ L +K N ++TE+ E + C R+ EL D L Q
Sbjct: 203 VKKNILAEELSTNK--NQL-KQLTETYEEDRKNYSEVQIRCQ-RLALELA--DTKQLIQQ 256
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA----ETKLKSEVTRIKKKLQI 332
+ ++ + +D V D+ +Q IE+ + + ++EA +TK +SE+++ L+
Sbjct: 257 GDYRQ--ENYD--KVKSERDALEQEVIELRRKH-EILEASHMIQTKERSELSKEVVTLEQ 311
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+T L+ + N+ N++L + +L +Q +E ++ + ++Y ++ ++
Sbjct: 312 TVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKT 371
Query: 393 -----LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA 447
L E+E+IR Q + R+ ++ E + R N+ + A E+E A
Sbjct: 372 EYENKLHDELEQIRLKTNQEIDQLRNASREMYERENR-------NLREARDNAVAEKERA 424
Query: 448 IVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI 505
++ A+ D + K ++ D RY+ +Q TE K T E LH+ + + + E V+ E +N+
Sbjct: 425 VM-AEKDALEKHDQLLD-RYRELQLSTESKVT-EFLHQSKLKSFESERVQLLQEETARNL 481
Query: 506 S---VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + E+ + V K S L+A + EL + H + I K E++L E+
Sbjct: 482 TQCQLECEKYQKKLEVLTKEFYS-LQASSEKRITELQAQNSEHQARLDIYEKLEKELDEI 540
Query: 563 IIQCEE 568
I+Q E
Sbjct: 541 IMQTAE 546
Score = 32.7 bits (71), Expect = 4.3
Identities = 64/375 (17%), Positives = 158/375 (42%), Gaps = 26/375 (6%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI---EIEQLNAR---VVEAE 316
T++ ++ + L++ + + D+ + D+SK + E+E + R + E
Sbjct: 83 TKIEELEEKLNDALHQKQLLTLRLDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETN 142
Query: 317 TKLKSEVTRIKKKLQ-IQITELE-LSLDVANKTNIDLQKTIKKQSLQLTE-IQTHYDEVQ 373
+L+ + +++ L+ ++TE + + L + + + + + + +L ++ E+Q
Sbjct: 143 LQLREKAGDVRRNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVRFYELVNPLRKEICELQ 202
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY-EQALRVKR-SVEQQYEESQTRVNELTVI 431
+ + ++ + +++ LT EE R NY E +R +R ++E + + +
Sbjct: 203 VKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQE 262
Query: 432 NVN-LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE---LKHTVEHLHEEQER 487
N + + S + +EQE+ + ++ + I + + E L+ TV L +++E
Sbjct: 263 NYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKE- 321
Query: 488 IVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK---RIISKLEARIKDMELELDEEKRR 544
+ L + + RLE ++A K + K A + E + +
Sbjct: 322 --YLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKLHD 379
Query: 545 HAETIKILRKKE-RQLKEVIIQC-EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
E I++ +E QL+ + E + +N+ +D+ ++ + ++ E+
Sbjct: 380 ELEQIRLKTNQEIDQLRNASREMYERENRNLREARDNAVAEKERAVMAEKDALEKH---D 436
Query: 603 QSVTRVRRFQRELEA 617
Q + R R Q E+
Sbjct: 437 QLLDRYRELQLSTES 451
Score = 31.5 bits (68), Expect = 9.9
Identities = 31/111 (27%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-- 609
L + QLK++ EED+KN S +Q ++ + +++ K QL +Q Q++ +V+
Sbjct: 212 LSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTK-QLIQQGDYRQENYDKVKSE 270
Query: 610 RFQRELEAAEDRA--DVAESNLSLIRAKHRTFVTTSTVPGSQ-VYLVQESR 657
R E E E R ++ E++ +I+ K R+ ++ V Q V L+Q+ +
Sbjct: 271 RDALEQEVIELRRKHEILEAS-HMIQTKERSELSKEVVTLEQTVTLLQKDK 320
>AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens
cDNA FLJ16459 fis, clone BRCAN2002473, moderately
similar to Tropomyosin, fibroblast isoform 2. ).
Length = 326
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/246 (21%), Positives = 119/246 (48%), Gaps = 12/246 (4%)
Query: 314 EAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
EA KL+ E+ ++KKL+ TE EL D ++ D Q+ ++ + T+ + +
Sbjct: 76 EAAAKLEDELVSLQKKLKG--TEDEL--DKYSEALKDAQEKLELAEKKATDAEADVASLN 131
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ--QYEESQTRVNELTVI 431
R++Q+ ++ AQ R+ + ++EE +++ R + +E Q +E + + E+ +
Sbjct: 132 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLK 191
Query: 432 NVNLSSSKA-----KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQE 486
+ A ++ ++L I+ +D + + +++ + ++ ELK +L +
Sbjct: 192 EAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEA 251
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
+ K + E E+K +S +L+E E A +R ++KLE I D+E ++ K +
Sbjct: 252 QAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF-AERSVTKLEKSIDDLEEKVAHAKEENL 310
Query: 547 ETIKIL 552
++L
Sbjct: 311 SMHQML 316
Score = 52.0 bits (119), Expect = 7e-06
Identities = 54/257 (21%), Positives = 108/257 (42%), Gaps = 22/257 (8%)
Query: 349 IDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL 408
+ LQK +K +L + + Q +L++ + A+ + SL ++ + ++A
Sbjct: 86 VSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQ 145
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQ 468
+ Q+ EE++ +E + S K E+++ I E AD +Y+
Sbjct: 146 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 205
Query: 469 RVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLE 528
V +L L +ER E LE E+K ++ L+ +EA A
Sbjct: 206 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE----------- 254
Query: 529 ARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
+ +++ R+ E IK+L K LKE + E +++++ L+ S++ +KV+
Sbjct: 255 --------KYSQKEDRYEEEIKVLSDK---LKEAETRAEFAERSVTKLEKSIDDLEEKVA 303
Query: 589 IYKRQLAEQEGMSQQSV 605
K + M Q++
Sbjct: 304 HAKEENLSMHQMLDQTL 320
Score = 47.6 bits (108), Expect = 1e-04
Identities = 42/195 (21%), Positives = 92/195 (47%), Gaps = 15/195 (7%)
Query: 458 KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAI 517
K LR++++ RV EL + L +E K+E SL+ ++K L++ + A+
Sbjct: 48 KLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKY-SEAL 106
Query: 518 VGGKRIISKLEARIKDMELELDEEKRR-HAETIKILRKKER------QLKEVIIQCEEDQ 570
+ + E + D E ++ RR ++ R +ER +L+E +E +
Sbjct: 107 KDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 166
Query: 571 KNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR-------ELEAAEDRAD 623
+ + +++ +K +K+ I + QL E + +++ + + R +LE AE+RA+
Sbjct: 167 RGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAE 226
Query: 624 VAESNLSLIRAKHRT 638
++E + + + +T
Sbjct: 227 LSEGKCAELEEELKT 241
>AF330046-1|AAL37481.1| 757|Homo sapiens progesterone-induced
blocking factor 1 protein.
Length = 757
Score = 66.5 bits (155), Expect = 3e-10
Identities = 88/366 (24%), Positives = 171/366 (46%), Gaps = 36/366 (9%)
Query: 217 LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQL 276
+ KN+LA+ L +K N ++TE+ E + C R+ EL D L Q
Sbjct: 203 VKKNILAEELSTNK--NQL-KQLTETYEEDRKNYSEVQIRCQ-RLALELA--DTKQLIQQ 256
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA----ETKLKSEVTRIKKKLQI 332
+ ++ + +D V D+ +Q IE+ + + ++EA +TK +SE+++ L+
Sbjct: 257 GDYRQ--ENYD--KVKSERDALEQEVIELRRKH-EILEASHMIQTKERSELSKEVVTLEQ 311
Query: 333 QITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
+T L+ + N+ N++L + +L +Q +E ++ + ++Y ++ ++
Sbjct: 312 TVTLLQKDKEYLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKT 371
Query: 393 -----LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA 447
L E+E+IR Q + R+ ++ E + R N+ + A E+E A
Sbjct: 372 EYENKLHDELEQIRLKTNQEIDQLRNASREMYERENR-------NLREARDNAVAEKERA 424
Query: 448 IVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI 505
++ A+ D + K ++ D RY+ +Q TE K T E LH+ + + + E V+ E +N+
Sbjct: 425 VM-AEKDALEKHDQLLD-RYRELQLSTESKVT-EFLHQSKLKSFESERVQLLQEETARNL 481
Query: 506 S---VRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + E+ + V K S L+A + EL + H + I K E++L E+
Sbjct: 482 TQCQLECEKYQKKLEVLTKEFYS-LQASSEKRITELQAQNSEHQARLDIYEKLEKELDEI 540
Query: 563 IIQCEE 568
I+Q E
Sbjct: 541 IMQTAE 546
Score = 32.7 bits (71), Expect = 4.3
Identities = 64/375 (17%), Positives = 158/375 (42%), Gaps = 26/375 (6%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI---EIEQLNAR---VVEAE 316
T++ ++ + L++ + + D+ + D+SK + E+E + R + E
Sbjct: 83 TKIEELEEKLNDALHQKQLLTLRLDNQLAFQQKDASKYQELMKQEMETILLRQKQLEETN 142
Query: 317 TKLKSEVTRIKKKLQ-IQITELE-LSLDVANKTNIDLQKTIKKQSLQLTE-IQTHYDEVQ 373
+L+ + +++ L+ ++TE + + L + + + + + + +L ++ E+Q
Sbjct: 143 LQLREKAGDVRRNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVRFYELVNPLRKEICELQ 202
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY-EQALRVKR-SVEQQYEESQTRVNELTVI 431
+ + ++ + +++ LT EE R NY E +R +R ++E + + +
Sbjct: 203 VKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTKQLIQQGDYRQE 262
Query: 432 NVN-LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE---LKHTVEHLHEEQER 487
N + + S + +EQE+ + ++ + I + + E L+ TV L +++E
Sbjct: 263 NYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKEVVTLEQTVTLLQKDKE- 321
Query: 488 IVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK---RIISKLEARIKDMELELDEEKRR 544
+ L + + RLE ++A K + K A + E + +
Sbjct: 322 --YLNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKLHD 379
Query: 545 HAETIKILRKKE-RQLKEVIIQC-EEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
E I++ +E QL+ + E + +N+ +D+ ++ + ++ E+
Sbjct: 380 ELEQIRLKTNQEIDQLRNASREMYERENRNLREARDNAVAEKERAVMAEKDALEKH---D 436
Query: 603 QSVTRVRRFQRELEA 617
Q + R R Q E+
Sbjct: 437 QLLDRYRELQLSTES 451
Score = 31.5 bits (68), Expect = 9.9
Identities = 31/111 (27%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-- 609
L + QLK++ EED+KN S +Q ++ + +++ K QL +Q Q++ +V+
Sbjct: 212 LSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALELADTK-QLIQQGDYRQENYDKVKSE 270
Query: 610 RFQRELEAAEDRA--DVAESNLSLIRAKHRTFVTTSTVPGSQ-VYLVQESR 657
R E E E R ++ E++ +I+ K R+ ++ V Q V L+Q+ +
Sbjct: 271 RDALEQEVIELRRKHEILEAS-HMIQTKERSELSKEVVTLEQTVTLLQKDK 320
>AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein.
Length = 1416
Score = 66.5 bits (155), Expect = 3e-10
Identities = 89/414 (21%), Positives = 191/414 (46%), Gaps = 42/414 (10%)
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
+ K T K+ D L++ +++ S+ E++ E + KLK E+ ++K L+ + +
Sbjct: 997 KFKATEKELKDQ----LSEQTQKYSVSEEEVKKNKQEND-KLKKEIFTLQKDLRDKTVLI 1051
Query: 338 ELSLDV----ANKTNIDLQKTIKKQSLQLTEIQTH----YDEVQRQLQVTLDQYGVAQRR 389
E S ++ + KT+ +L K +K S + TE++ +E +Q L + Q++
Sbjct: 1052 EKSHEMERALSRKTD-ELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQ 1110
Query: 390 ---IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS-------- 438
++ + + + G E +S+++ YE+ Q V +L + N +S
Sbjct: 1111 HVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHL 1170
Query: 439 --KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV----KIE 492
K E+E+ I+ A E +E + E ++Q+E+++T + L + + R V K +
Sbjct: 1171 QIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYK 1230
Query: 493 AVKKSLEIEVKNISVRL-------EEVEANAIVGGKRIIS-KLEARIK--DMELELDEEK 542
A K LE ++ +++ +L EEV + K+ IS K E + +E E+ ++K
Sbjct: 1231 ATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQK 1290
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
R +++ + + +R+++E Q E I+ L + +E+ Q ++ + ++
Sbjct: 1291 ERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTK 1350
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES 656
+ + Q ++++ E + A+ + A +RT + S G VQE+
Sbjct: 1351 RQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHL-LSAAQGHMDEDVQEA 1403
Score = 50.4 bits (115), Expect = 2e-05
Identities = 61/304 (20%), Positives = 139/304 (45%), Gaps = 27/304 (8%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S+KQ ++++ A V L E R+K+ QI +LE +L D+QK +
Sbjct: 454 ESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALK-------DVQKRM 506
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ ++ ++QTH+ ++ L T + R + L ++++++ YE A +
Sbjct: 507 YESEGKVKQMQTHFLALKEHL--TSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLR 564
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q ++++ V E L ++++EL++ + ++ +++ + + + + +L
Sbjct: 565 NQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLA 624
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
++ K E +K SL EV + +L E+E R K + I+ ++
Sbjct: 625 LSIP--------AEKFENMKSSLSNEVNEKAKKLVEME--------REHEKSLSEIRQLK 668
Query: 536 LELDEEKRRHAETIKILRKKE--RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
EL+ K + A+ +K ++ +L++ + + ++L +L+K +KV + +
Sbjct: 669 RELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKL 728
Query: 594 LAEQ 597
L EQ
Sbjct: 729 LKEQ 732
Score = 42.7 bits (96), Expect = 0.004
Identities = 72/354 (20%), Positives = 168/354 (47%), Gaps = 39/354 (11%)
Query: 277 NELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLN---ARVVEAETKLKSEVTRI---KK 328
++LK+ +++ S + L + KQ + +E+ +++E +L+ E++ ++
Sbjct: 544 DQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMERE 603
Query: 329 KLQIQITELE-----LSLDVANKTNIDLQKTIKKQ-SLQLTEIQTHYDEVQRQLQVTLDQ 382
K ++TE+E LS +A + + +K S ++ E E++R+ + +L +
Sbjct: 604 KKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSE 663
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+R ++++ ++ + E+ +VK +EQ+ E ++ ELT+ N L K+
Sbjct: 664 IRQLKRELENVKAKLAQ-HVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKV 722
Query: 443 EQELAIVAADYDEITKELRIADERY--QRVQTELKHTVEHLHEEQER---IVKIEAVKKS 497
+ ++ +T E++ Y +V ++K + + + ++ R V + +K
Sbjct: 723 YLDNKLLKEQAHNLTIEMK---NHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKK 779
Query: 498 LEIE---VKNISV-----RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR---HA 546
LE+E ++N S+ RLE V K II+ L++ I +++ +L E K++
Sbjct: 780 LEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIA-LKSNIVELKKQLSELKKKCGEDQ 838
Query: 547 ETIKILRKKERQLKEVI----IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
E I L + LK+++ + + ++ L D+L KT++++ K++ +
Sbjct: 839 EKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFED 892
Score = 39.9 bits (89), Expect = 0.028
Identities = 55/248 (22%), Positives = 113/248 (45%), Gaps = 16/248 (6%)
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI---KKQSLQLTEIQTHYDEVQRQLQ 377
SE +KK+L+ T E + K +L + K +L+ ++ DE +QL+
Sbjct: 437 SENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLE 496
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
L Q+R+ G+V++++ ++ L +K + + R+ E + L
Sbjct: 497 DALKD---VQKRMYESEGKVKQMQTHF---LALKEHLTSEAASGNHRLTE--ELKDQLKD 548
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
K K E A V ++I + I +E ++R + +L + L +E + ++E KK
Sbjct: 549 LKVKYEGASAEVGKLRNQIKQNEMIVEE-FKRDEGKLIEENKRLQKELS-MCEMEREKKG 606
Query: 498 LEI-EVKNISVRLEEVEANAIVGGK--RIISKLEARIKDMELELDEEKRRHAETIKILRK 554
++ E++ + L A +I K + S L + + +L E +R H +++ +R+
Sbjct: 607 RKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQ 666
Query: 555 KERQLKEV 562
+R+L+ V
Sbjct: 667 LKRELENV 674
Score = 39.9 bits (89), Expect = 0.028
Identities = 82/381 (21%), Positives = 165/381 (43%), Gaps = 41/381 (10%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYR-----GKSAKAIAQTLLEESRRNVQNER 197
KK + ++K DL +K V + + A+ R K K ++Q E +NV+ +
Sbjct: 1034 KKEIFTLQK--DLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEV--KNVKEKL 1089
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
+ + Q S L ++ L + K++N + E + R E T
Sbjct: 1090 VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQT- 1148
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
V +++ L NS + L+ +K+ + V I+ S + E E+ + +E +
Sbjct: 1149 VTKLHQLLENQKNSSVPLAEHLQ--IKEAFEKEVGIIKASLR----EKEEESQNKMEEVS 1202
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL+SEV K+ L+ T + L T DL+ I + +L + Y+EV ++
Sbjct: 1203 KLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV- 1261
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE-LTVINVNLS 436
L + +EI E+ L + S+EQ+ ++ + R ++ LT I +
Sbjct: 1262 ---------------LHAKKKEISAKDEKEL-LHFSIEQEIKDQKERCDKSLTTI----T 1301
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIV-KIEA 493
+ +I++ + A ++IT+ L + Q + ++L +T + + Q +++ ++
Sbjct: 1302 ELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQH 1361
Query: 494 VKKSLEIEVKNISVRLEEVEA 514
KSLE ++ + + +EV A
Sbjct: 1362 QVKSLEQQLADADRQHQEVIA 1382
>AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein.
Length = 1416
Score = 66.5 bits (155), Expect = 3e-10
Identities = 89/414 (21%), Positives = 191/414 (46%), Gaps = 42/414 (10%)
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
+ K T K+ D L++ +++ S+ E++ E + KLK E+ ++K L+ + +
Sbjct: 997 KFKATEKELKDQ----LSEQTQKYSVSEEEVKKNKQEND-KLKKEIFTLQKDLRDKTVLI 1051
Query: 338 ELSLDV----ANKTNIDLQKTIKKQSLQLTEIQTH----YDEVQRQLQVTLDQYGVAQRR 389
E S ++ + KT+ +L K +K S + TE++ +E +Q L + Q++
Sbjct: 1052 EKSHEMERALSRKTD-ELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQ 1110
Query: 390 ---IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSS-------- 438
++ + + + G E +S+++ YE+ Q V +L + N +S
Sbjct: 1111 HVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHL 1170
Query: 439 --KAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV----KIE 492
K E+E+ I+ A E +E + E ++Q+E+++T + L + + R V K +
Sbjct: 1171 QIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYK 1230
Query: 493 AVKKSLEIEVKNISVRL-------EEVEANAIVGGKRIIS-KLEARIK--DMELELDEEK 542
A K LE ++ +++ +L EEV + K+ IS K E + +E E+ ++K
Sbjct: 1231 ATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQK 1290
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
R +++ + + +R+++E Q E I+ L + +E+ Q ++ + ++
Sbjct: 1291 ERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTK 1350
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQES 656
+ + Q ++++ E + A+ + A +RT + S G VQE+
Sbjct: 1351 RQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHL-LSAAQGHMDEDVQEA 1403
Score = 50.4 bits (115), Expect = 2e-05
Identities = 61/304 (20%), Positives = 139/304 (45%), Gaps = 27/304 (8%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S+KQ ++++ A V L E R+K+ QI +LE +L D+QK +
Sbjct: 454 ESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALK-------DVQKRM 506
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
+ ++ ++QTH+ ++ L T + R + L ++++++ YE A +
Sbjct: 507 YESEGKVKQMQTHFLALKEHL--TSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLR 564
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
Q ++++ V E L ++++EL++ + ++ +++ + + + + +L
Sbjct: 565 NQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLA 624
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
++ K E +K SL EV + +L E+E R K + I+ ++
Sbjct: 625 LSIP--------AEKFENMKSSLSNEVNEKAKKLVEME--------REHEKSLSEIRQLK 668
Query: 536 LELDEEKRRHAETIKILRKKE--RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
EL+ K + A+ +K ++ +L++ + + ++L +L+K +KV + +
Sbjct: 669 RELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKL 728
Query: 594 LAEQ 597
L EQ
Sbjct: 729 LKEQ 732
Score = 42.7 bits (96), Expect = 0.004
Identities = 72/354 (20%), Positives = 168/354 (47%), Gaps = 39/354 (11%)
Query: 277 NELKETVKQFDDLSVYI--LNDSSKQTSIEIEQLN---ARVVEAETKLKSEVTRI---KK 328
++LK+ +++ S + L + KQ + +E+ +++E +L+ E++ ++
Sbjct: 544 DQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMERE 603
Query: 329 KLQIQITELE-----LSLDVANKTNIDLQKTIKKQ-SLQLTEIQTHYDEVQRQLQVTLDQ 382
K ++TE+E LS +A + + +K S ++ E E++R+ + +L +
Sbjct: 604 KKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSE 663
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+R ++++ ++ + E+ +VK +EQ+ E ++ ELT+ N L K+
Sbjct: 664 IRQLKRELENVKAKLAQ-HVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKV 722
Query: 443 EQELAIVAADYDEITKELRIADERY--QRVQTELKHTVEHLHEEQER---IVKIEAVKKS 497
+ ++ +T E++ Y +V ++K + + + ++ R V + +K
Sbjct: 723 YLDNKLLKEQAHNLTIEMK---NHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKK 779
Query: 498 LEIE---VKNISV-----RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRR---HA 546
LE+E ++N S+ RLE V K II+ L++ I +++ +L E K++
Sbjct: 780 LEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIA-LKSNIVELKKQLSELKKKCGEDQ 838
Query: 547 ETIKILRKKERQLKEVI----IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
E I L + LK+++ + + ++ L D+L KT++++ K++ +
Sbjct: 839 EKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFED 892
Score = 39.9 bits (89), Expect = 0.028
Identities = 55/248 (22%), Positives = 113/248 (45%), Gaps = 16/248 (6%)
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI---KKQSLQLTEIQTHYDEVQRQLQ 377
SE +KK+L+ T E + K +L + K +L+ ++ DE +QL+
Sbjct: 437 SENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLE 496
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
L Q+R+ G+V++++ ++ L +K + + R+ E + L
Sbjct: 497 DALKD---VQKRMYESEGKVKQMQTHF---LALKEHLTSEAASGNHRLTE--ELKDQLKD 548
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
K K E A V ++I + I +E ++R + +L + L +E + ++E KK
Sbjct: 549 LKVKYEGASAEVGKLRNQIKQNEMIVEE-FKRDEGKLIEENKRLQKELS-MCEMEREKKG 606
Query: 498 LEI-EVKNISVRLEEVEANAIVGGK--RIISKLEARIKDMELELDEEKRRHAETIKILRK 554
++ E++ + L A +I K + S L + + +L E +R H +++ +R+
Sbjct: 607 RKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQ 666
Query: 555 KERQLKEV 562
+R+L+ V
Sbjct: 667 LKRELENV 674
Score = 39.9 bits (89), Expect = 0.028
Identities = 82/381 (21%), Positives = 165/381 (43%), Gaps = 41/381 (10%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYR-----GKSAKAIAQTLLEESRRNVQNER 197
KK + ++K DL +K V + + A+ R K K ++Q E +NV+ +
Sbjct: 1034 KKEIFTLQK--DLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEV--KNVKEKL 1089
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
+ + Q S L ++ L + K++N + E + R E T
Sbjct: 1090 VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQT- 1148
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
V +++ L NS + L+ +K+ + V I+ S + E E+ + +E +
Sbjct: 1149 VTKLHQLLENQKNSSVPLAEHLQ--IKEAFEKEVGIIKASLR----EKEEESQNKMEEVS 1202
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL+SEV K+ L+ T + L T DL+ I + +L + Y+EV ++
Sbjct: 1203 KLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV- 1261
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE-LTVINVNLS 436
L + +EI E+ L + S+EQ+ ++ + R ++ LT I +
Sbjct: 1262 ---------------LHAKKKEISAKDEKEL-LHFSIEQEIKDQKERCDKSLTTI----T 1301
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQ--TELKHTVEHLHEEQERIV-KIEA 493
+ +I++ + A ++IT+ L + Q + ++L +T + + Q +++ ++
Sbjct: 1302 ELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQH 1361
Query: 494 VKKSLEIEVKNISVRLEEVEA 514
KSLE ++ + + +EV A
Sbjct: 1362 QVKSLEQQLADADRQHQEVIA 1382
>X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal
muscle 1.3 kb mRNA for tropomyosin. ).
Length = 285
Score = 66.1 bits (154), Expect = 4e-10
Identities = 56/258 (21%), Positives = 123/258 (47%), Gaps = 14/258 (5%)
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKT 354
N + E EQ A E +L+ E+ ++KKL+ TE EL D ++ D Q+
Sbjct: 18 NALDRAEQAEAEQKQAE--ERSKQLEDELAAMQKKLKG--TEDEL--DKYSEALKDAQEK 71
Query: 355 IKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++ + + + + R++Q+ ++ AQ R+ + ++EE +++ R + +
Sbjct: 72 LELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 131
Query: 415 EQQY--EESQTRVNELTVINVNLSSSKA-----KIEQELAIVAADYDEITKELRIADERY 467
E + +E + + E+ + + +A ++ ++L I+ D + + +A+ +
Sbjct: 132 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKC 191
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
++ ELK+ +L + + K + E E+K ++ +L+E E A +R ++KL
Sbjct: 192 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEF-AERSVAKL 250
Query: 528 EARIKDMELELDEEKRRH 545
E I D+E EL +K ++
Sbjct: 251 EKTIDDLEDELYAQKLKY 268
Score = 47.6 bits (108), Expect = 1e-04
Identities = 43/197 (21%), Positives = 96/197 (48%), Gaps = 24/197 (12%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+++E A+ A+ E E + A+ER ++++ EL + L ++ + K K +
Sbjct: 13 KLDKENALDRAEQAEA--EQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQE 70
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+++ + + EA ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 71 KLELAEKKAADAEAE--------VASLNRRIQLVEEELDRAQERLATALQKLEEAEKA-- 120
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------- 613
+E ++ + ++++ K +K+ + + QL E + +++++ + R
Sbjct: 121 -----ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 175
Query: 614 ELEAAEDRADVAESNLS 630
+LE E+RA++AES S
Sbjct: 176 DLERTEERAELAESKCS 192
>L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory
factor protein.
Length = 1093
Score = 66.1 bits (154), Expect = 4e-10
Identities = 100/471 (21%), Positives = 200/471 (42%), Gaps = 35/471 (7%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSK--NVLAKALMESKAMNSCDS--RVTE 241
+EES R+ +PD S T +N T L K A + +A++ + + E
Sbjct: 393 MEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVE 452
Query: 242 SITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQT 301
+ E + RE ++ ++ E ++ ++ N +E+ VK+ + S+ L D Q
Sbjct: 453 FLNEKLEKREAQ----LLSLSKEKALLEEAFDNLKDEMFR-VKE-ESSSISSLKDEFTQR 506
Query: 302 SIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ 361
E E+ + K E+ IK++L ++ E + D+ + + + + + ++ +
Sbjct: 507 IAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETA-DLLKEKDEQI-RGLMEEGEK 564
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L++ Q H + ++L+ + ++ E+EE + +Q L K VE+Q+ E+
Sbjct: 565 LSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHREN 624
Query: 422 QTRVN--------ELTVINVNLSSSKAKIEQELAIVAADYDEIT---KELRIADERYQR- 469
++N +L + V++ + K A + + Y E+T K D Q
Sbjct: 625 IKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEA 684
Query: 470 -VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLE 528
+ E+K E ++ + +++L I+V ++ + L+ E A R L
Sbjct: 685 ALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAA----ARKEDYLR 740
Query: 529 ARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
I +++ L E + R+ E + + R L + Q E Q + S EK + +S
Sbjct: 741 HEIGELQQRLQEAENRNQELSQSVSSTTRPL---LRQIENLQATLGSQTSSWEKLEKNLS 797
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+L E + + +V R R EL A + + ES SL+R ++ F
Sbjct: 798 ---DRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRF 845
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/377 (18%), Positives = 160/377 (42%), Gaps = 14/377 (3%)
Query: 219 KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNS--YLNQL 276
K+ + LME S +I + +R ++ V ++N ++ ++ +L Q+
Sbjct: 551 KDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQV 610
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+ KE V++ ++ LN ++ ++ +L + E E K +S + + ++T+
Sbjct: 611 LDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYK-ELTD 669
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
L + A K + + + ++ E+ ++ Q + + + + ++
Sbjct: 670 LHKAN--AAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQR 727
Query: 397 VEEIRGNYEQALRVK-RSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQELAIVAADYD 454
E+ E LR + ++Q+ +E++ R EL+ ++ +IE A + +
Sbjct: 728 TEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTS 787
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
K + +R QT L VE E ++ + S+E + N +R E
Sbjct: 788 SWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQ--NSLLRQENSRF 845
Query: 515 NA-IVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKE----RQLKEVIIQCEED 569
A + K + KLE ++EL+ K + T++ RK++ QL+ ++ E++
Sbjct: 846 QAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQE 905
Query: 570 QKNISLLQDSLEKTSQK 586
+K Q+++++ +K
Sbjct: 906 RKKAIFTQETIKEKERK 922
>D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein.
Length = 1593
Score = 66.1 bits (154), Expect = 4e-10
Identities = 79/347 (22%), Positives = 173/347 (49%), Gaps = 28/347 (8%)
Query: 279 LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS---EVTRIKKKLQIQIT 335
L+E ++ D+ + ++ ++ E+ + +++E E + S E+ +K+ +I +
Sbjct: 904 LEEVLQNKDNEFALVKHEKEAVICLQNEK-DQKLLEMENIMHSQNCEIKELKQSREIVLE 962
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L+ L V N + L + + QSL+ Q+H E++ LQV Q ++ +
Sbjct: 963 DLK-KLHVENDEKLQLLRA-ELQSLE----QSHLKELEDTLQVRHIQE--FEKVMTDHRV 1014
Query: 396 EVEEIRGNYEQAL-RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
+EE++ +Q + +++ S + +E + ++ EL + +LS ++ K+E ELA+ A+ D
Sbjct: 1015 SLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETD 1074
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
EI ++ + + R Q+ +T LK +E E + +I + + ++ +N V L E+
Sbjct: 1075 EI--KILLEESRAQQKET-LKSLLE--QETENLRTEISKLNQKIQDNNENYQVGLAELRT 1129
Query: 515 NAIVGGKRIISKLEARIKD----MELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-- 568
+ + IS+L +R ++ ++ EL++ H + +I E+ LKE II+ +
Sbjct: 1130 LMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEI----EKNLKEQIIELQSKL 1185
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
D + +L + EK +Q+ Y+ + E Q+ V+ + + +L
Sbjct: 1186 DSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQL 1232
Score = 52.8 bits (121), Expect = 4e-06
Identities = 63/332 (18%), Positives = 152/332 (45%), Gaps = 18/332 (5%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + + I +E L VE + KL+ ++ Q + ELE +L V + + +K
Sbjct: 950 IKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQ--EFEK 1007
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVT-LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
+ + L E++ ++ Q+Q + + ++++Q L +V ++ R K
Sbjct: 1008 VMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDT-----RCKL 1062
Query: 413 SVEQQYEESQTRVNELTVINVNLSSS---KAKIEQELAIVAADYDEITKELRIADERYQR 469
VE +E++T ++ + K+ +EQE + + ++ ++++ +E YQ
Sbjct: 1063 EVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQV 1122
Query: 470 VQTELKH--TVEHLHEEQERIVKIEAVKKSLEIEVKNISV---RLEEVEANAIVGGKRII 524
EL+ T+E E I + E L+ E+ ++ + E+E N +
Sbjct: 1123 GLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQ 1182
Query: 525 SKLEARIKDMELELDEEKRRHAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
SKL++ + +E + DE+ + E + I++ E+ ++++ E+D++ + + + + EK
Sbjct: 1183 SKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQL-IQKLNCEKD 1241
Query: 584 SQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ K E+E + ++ + +V+ + ++
Sbjct: 1242 EAIQTALKEFKLEREVVEKELLEKVKHLENQI 1273
Score = 45.6 bits (103), Expect = 6e-04
Identities = 77/369 (20%), Positives = 161/369 (43%), Gaps = 29/369 (7%)
Query: 247 VRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
++V + S T C + + L + + L L+E+ Q + +L ++ EI
Sbjct: 1050 LKVSDLSDTRCKLEVELALKEAETDEIKIL--LEESRAQQKETLKSLLEQETENLRTEIS 1107
Query: 307 QLNARVVEAETKLKSEVTRIKKKLQIQITEL--ELSLDVANKTNIDLQKTIKKQSL--QL 362
+LN ++ + + + ++ + I+ + EL ++NI + K SL Q
Sbjct: 1108 KLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQA 1167
Query: 363 TEIQTHYDEVQRQLQVTLD-QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
EI+ + E +LQ LD + +R+ + EE YE ++ Q+ S
Sbjct: 1168 FEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEE---KYEAIIQNLEKDRQKLVSS 1224
Query: 422 QTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
Q + E + +N E++ AI A KE ++ ER + V+ EL V+HL
Sbjct: 1225 QEQDREQLIQKLNC-------EKDEAIQTA-----LKEFKL--ER-EVVEKELLEKVKHL 1269
Query: 482 HEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE 541
+ + I++ + V + +L+E +A + + + ++++ L E
Sbjct: 1270 ENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAE 1329
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK-TSQKVSIYKRQLAEQEGM 600
++ + T+ + R+K R KE II D+ ++ Q +K + +S + +L E++
Sbjct: 1330 QQTNFNTV-LTREKMR--KENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKK 1386
Query: 601 SQQSVTRVR 609
++ V+++R
Sbjct: 1387 LEEEVSKLR 1395
>BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory
factor 1 protein.
Length = 1093
Score = 66.1 bits (154), Expect = 4e-10
Identities = 100/471 (21%), Positives = 200/471 (42%), Gaps = 35/471 (7%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSK--NVLAKALMESKAMNSCDS--RVTE 241
+EES R+ +PD S T +N T L K A + +A++ + + E
Sbjct: 393 MEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVE 452
Query: 242 SITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQT 301
+ E + RE ++ ++ E ++ ++ N +E+ VK+ + S+ L D Q
Sbjct: 453 FLNEKLEKREAQ----LLSLSKEKALLEEAFDNLKDEMFR-VKE-ESSSISSLKDEFTQR 506
Query: 302 SIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ 361
E E+ + K E+ IK++L ++ E + D+ + + + + + ++ +
Sbjct: 507 IAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETA-DLLKEKDEQI-RGLMEEGEK 564
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L++ Q H + ++L+ + ++ E+EE + +Q L K VE+Q+ E+
Sbjct: 565 LSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHREN 624
Query: 422 QTRVN--------ELTVINVNLSSSKAKIEQELAIVAADYDEIT---KELRIADERYQR- 469
++N +L + V++ + K A + + Y E+T K D Q
Sbjct: 625 IKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEA 684
Query: 470 -VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLE 528
+ E+K E ++ + +++L I+V ++ + L+ E A R L
Sbjct: 685 ALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAA----ARKEDYLR 740
Query: 529 ARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
I +++ L E + R+ E + + R L + Q E Q + S EK + +S
Sbjct: 741 HEIGELQQRLQEAENRNQELSQSVSSTTRPL---LRQIENLQATLGSQTSSWEKLEKNLS 797
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+L E + + +V R R EL A + + ES SL+R ++ F
Sbjct: 798 ---DRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRF 845
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/377 (18%), Positives = 160/377 (42%), Gaps = 14/377 (3%)
Query: 219 KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNS--YLNQL 276
K+ + LME S +I + +R ++ V ++N ++ ++ +L Q+
Sbjct: 551 KDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQV 610
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+ KE V++ ++ LN ++ ++ +L + E E K +S + + ++T+
Sbjct: 611 LDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYK-ELTD 669
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
L + A K + + + ++ E+ ++ Q + + + + ++
Sbjct: 670 LHKAN--AAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQR 727
Query: 397 VEEIRGNYEQALRVK-RSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQELAIVAADYD 454
E+ E LR + ++Q+ +E++ R EL+ ++ +IE A + +
Sbjct: 728 TEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTS 787
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
K + +R QT L VE E ++ + S+E + N +R E
Sbjct: 788 SWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQ--NSLLRQENSRF 845
Query: 515 NA-IVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKE----RQLKEVIIQCEED 569
A + K + KLE ++EL+ K + T++ RK++ QL+ ++ E++
Sbjct: 846 QAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQE 905
Query: 570 QKNISLLQDSLEKTSQK 586
+K Q+++++ +K
Sbjct: 906 RKKAIFTQETIKEKERK 922
>BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory
factor 1 protein.
Length = 1093
Score = 66.1 bits (154), Expect = 4e-10
Identities = 100/471 (21%), Positives = 200/471 (42%), Gaps = 35/471 (7%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSK--NVLAKALMESKAMNSCDS--RVTE 241
+EES R+ +PD S T +N T L K A + +A++ + + E
Sbjct: 393 MEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVE 452
Query: 242 SITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQT 301
+ E + RE ++ ++ E ++ ++ N +E+ VK+ + S+ L D Q
Sbjct: 453 FLNEKLEKREAQ----LLSLSKEKALLEEAFDNLKDEMFR-VKE-ESSSISSLKDEFTQR 506
Query: 302 SIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ 361
E E+ + K E+ IK++L ++ E + D+ + + + + + ++ +
Sbjct: 507 IAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETA-DLLKEKDEQI-RGLMEEGEK 564
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L++ Q H + ++L+ + ++ E+EE + +Q L K VE+Q+ E+
Sbjct: 565 LSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHREN 624
Query: 422 QTRVN--------ELTVINVNLSSSKAKIEQELAIVAADYDEIT---KELRIADERYQR- 469
++N +L + V++ + K A + + Y E+T K D Q
Sbjct: 625 IKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEA 684
Query: 470 -VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLE 528
+ E+K E ++ + +++L I+V ++ + L+ E A R L
Sbjct: 685 ALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAA----ARKEDYLR 740
Query: 529 ARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
I +++ L E + R+ E + + R L + Q E Q + S EK + +S
Sbjct: 741 HEIGELQQRLQEAENRNQELSQSVSSTTRPL---LRQIENLQATLGSQTSSWEKLEKNLS 797
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+L E + + +V R R EL A + + ES SL+R ++ F
Sbjct: 798 ---DRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRF 845
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/377 (18%), Positives = 160/377 (42%), Gaps = 14/377 (3%)
Query: 219 KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNS--YLNQL 276
K+ + LME S +I + +R ++ V ++N ++ ++ +L Q+
Sbjct: 551 KDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQV 610
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+ KE V++ ++ LN ++ ++ +L + E E K +S + + ++T+
Sbjct: 611 LDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYK-ELTD 669
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
L + A K + + + ++ E+ ++ Q + + + + ++
Sbjct: 670 LHKAN--AAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQR 727
Query: 397 VEEIRGNYEQALRVK-RSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQELAIVAADYD 454
E+ E LR + ++Q+ +E++ R EL+ ++ +IE A + +
Sbjct: 728 TEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTS 787
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
K + +R QT L VE E ++ + S+E + N +R E
Sbjct: 788 SWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQ--NSLLRQENSRF 845
Query: 515 NA-IVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKE----RQLKEVIIQCEED 569
A + K + KLE ++EL+ K + T++ RK++ QL+ ++ E++
Sbjct: 846 QAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQE 905
Query: 570 QKNISLLQDSLEKTSQK 586
+K Q+++++ +K
Sbjct: 906 RKKAIFTQETIKEKERK 922
>BC060037-1|AAH60037.1| 622|Homo sapiens KIAA1212 protein protein.
Length = 622
Score = 66.1 bits (154), Expect = 4e-10
Identities = 76/350 (21%), Positives = 161/350 (46%), Gaps = 21/350 (6%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S + S+E+ A++ +L+ + ++ Q ++ ++E+ L + N++L
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQ-ELEQMEIELKRLQQENMNLLSDA 302
Query: 356 KKQSLQLTEIQTHYDEVQR--QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ + E+ ++V R +L+ + +Y I+ VEE++ + + L K
Sbjct: 303 RSARMYRDELDALREKVVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTM 362
Query: 414 VEQQYEESQTR---VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
+E Q E ++ R ++EL N+ L + +E E + +E+ +E + ++
Sbjct: 363 LEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI-SVRLEEVEANAIVGGKRIISKLEA 529
E H L + EA +KSL EV + S RL ++E + + +L
Sbjct: 423 MDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-QSLTKTVEELRT 481
Query: 530 RIKDME------LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ +E L++++E +R ++ ++IL + Q K+ + C+ K++ + LEKT
Sbjct: 482 TVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKT 541
Query: 584 SQKV---SIYKRQLAEQEGMS-QQSVTRVRRFQRELEAAEDRA-DVAESN 628
+ + S + ++ EQE Q+V+ +R QR +AE R D+ + N
Sbjct: 542 IETLRENSERQIKILEQENEHLNQTVSSLR--QRSQISAEARVKDIEKEN 589
>BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-coil 1
protein.
Length = 1594
Score = 66.1 bits (154), Expect = 4e-10
Identities = 79/347 (22%), Positives = 173/347 (49%), Gaps = 28/347 (8%)
Query: 279 LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS---EVTRIKKKLQIQIT 335
L+E ++ D+ + ++ ++ E+ + +++E E + S E+ +K+ +I +
Sbjct: 902 LEEVLQNKDNEFALVKHEKEAVICLQNEK-DQKLLEMENIMHSQNCEIKELKQSREIVLE 960
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L+ L V N + L + + QSL+ Q+H E++ LQV Q ++ +
Sbjct: 961 DLK-KLHVENDEKLQLLRA-ELQSLE----QSHLKELEDTLQVRHIQE--FEKVMTDHRV 1012
Query: 396 EVEEIRGNYEQAL-RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
+EE++ +Q + +++ S + +E + ++ EL + +LS ++ K+E ELA+ A+ D
Sbjct: 1013 SLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETD 1072
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
EI ++ + + R Q+ +T LK +E E + +I + + ++ +N V L E+
Sbjct: 1073 EI--KILLEESRAQQKET-LKSLLE--QETENLRTEISKLNQKIQDNNENYQVGLAELRT 1127
Query: 515 NAIVGGKRIISKLEARIKD----MELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-- 568
+ + IS+L +R ++ ++ EL++ H + +I E+ LKE II+ +
Sbjct: 1128 LMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEI----EKNLKEQIIELQSKL 1183
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
D + +L + EK +Q+ Y+ + E Q+ V+ + + +L
Sbjct: 1184 DSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQL 1230
Score = 52.8 bits (121), Expect = 4e-06
Identities = 63/332 (18%), Positives = 152/332 (45%), Gaps = 18/332 (5%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + + I +E L VE + KL+ ++ Q + ELE +L V + + +K
Sbjct: 948 IKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQ--EFEK 1005
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVT-LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
+ + L E++ ++ Q+Q + + ++++Q L +V ++ R K
Sbjct: 1006 VMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDT-----RCKL 1060
Query: 413 SVEQQYEESQTRVNELTVINVNLSSS---KAKIEQELAIVAADYDEITKELRIADERYQR 469
VE +E++T ++ + K+ +EQE + + ++ ++++ +E YQ
Sbjct: 1061 EVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQV 1120
Query: 470 VQTELKH--TVEHLHEEQERIVKIEAVKKSLEIEVKNISV---RLEEVEANAIVGGKRII 524
EL+ T+E E I + E L+ E+ ++ + E+E N +
Sbjct: 1121 GLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQ 1180
Query: 525 SKLEARIKDMELELDEEKRRHAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
SKL++ + +E + DE+ + E + I++ E+ ++++ E+D++ + + + + EK
Sbjct: 1181 SKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQL-IQKLNCEKD 1239
Query: 584 SQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ K E+E + ++ + +V+ + ++
Sbjct: 1240 EAIQTALKEFKLEREVVEKELLEKVKHLENQI 1271
Score = 45.6 bits (103), Expect = 6e-04
Identities = 77/369 (20%), Positives = 161/369 (43%), Gaps = 29/369 (7%)
Query: 247 VRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
++V + S T C + + L + + L L+E+ Q + +L ++ EI
Sbjct: 1048 LKVSDLSDTRCKLEVELALKEAETDEIKIL--LEESRAQQKETLKSLLEQETENLRTEIS 1105
Query: 307 QLNARVVEAETKLKSEVTRIKKKLQIQITEL--ELSLDVANKTNIDLQKTIKKQSL--QL 362
+LN ++ + + + ++ + I+ + EL ++NI + K SL Q
Sbjct: 1106 KLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQA 1165
Query: 363 TEIQTHYDEVQRQLQVTLD-QYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
EI+ + E +LQ LD + +R+ + EE YE ++ Q+ S
Sbjct: 1166 FEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEE---KYEAIIQNLEKDRQKLVSS 1222
Query: 422 QTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
Q + E + +N E++ AI A KE ++ ER + V+ EL V+HL
Sbjct: 1223 QEQDREQLIQKLNC-------EKDEAIQTA-----LKEFKL--ER-EVVEKELLEKVKHL 1267
Query: 482 HEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE 541
+ + I++ + V + +L+E +A + + + ++++ L E
Sbjct: 1268 ENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAE 1327
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEK-TSQKVSIYKRQLAEQEGM 600
++ + T+ + R+K R KE II D+ ++ Q +K + +S + +L E++
Sbjct: 1328 QQTNFNTV-LTREKMR--KENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKK 1384
Query: 601 SQQSVTRVR 609
++ V+++R
Sbjct: 1385 LEEEVSKLR 1393
>BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein.
Length = 285
Score = 66.1 bits (154), Expect = 4e-10
Identities = 56/258 (21%), Positives = 123/258 (47%), Gaps = 14/258 (5%)
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKT 354
N + E EQ A E +L+ E+ ++KKL+ TE EL D ++ D Q+
Sbjct: 18 NALDRAEQAEAEQKQAE--ERSKQLEDELAAMQKKLKG--TEDEL--DKYSEALKDAQEK 71
Query: 355 IKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++ + + + + R++Q+ ++ AQ R+ + ++EE +++ R + +
Sbjct: 72 LELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 131
Query: 415 EQQY--EESQTRVNELTVINVNLSSSKA-----KIEQELAIVAADYDEITKELRIADERY 467
E + +E + + E+ + + +A ++ ++L I+ D + + +A+ +
Sbjct: 132 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKC 191
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
++ ELK+ +L + + K + E E+K ++ +L+E E A +R ++KL
Sbjct: 192 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEF-AERSVAKL 250
Query: 528 EARIKDMELELDEEKRRH 545
E I D+E EL +K ++
Sbjct: 251 EKTIDDLEDELYAQKLKY 268
Score = 47.6 bits (108), Expect = 1e-04
Identities = 43/197 (21%), Positives = 96/197 (48%), Gaps = 24/197 (12%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+++E A+ A+ E E + A+ER ++++ EL + L ++ + K K +
Sbjct: 13 KLDKENALDRAEQAEA--EQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQE 70
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+++ + + EA ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 71 KLELAEKKAADAEAE--------VASLNRRIQLVEEELDRAQERLATALQKLEEAEKA-- 120
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------- 613
+E ++ + ++++ K +K+ + + QL E + +++++ + R
Sbjct: 121 -----ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 175
Query: 614 ELEAAEDRADVAESNLS 630
+LE E+RA++AES S
Sbjct: 176 DLERTEERAELAESKCS 192
>BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein.
Length = 285
Score = 66.1 bits (154), Expect = 4e-10
Identities = 56/258 (21%), Positives = 123/258 (47%), Gaps = 14/258 (5%)
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKT 354
N + E EQ A E +L+ E+ ++KKL+ TE EL D ++ D Q+
Sbjct: 18 NALDRAEQAEAEQKQAE--ERSKQLEDELAAMQKKLKG--TEDEL--DKYSEALKDAQEK 71
Query: 355 IKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++ + + + + R++Q+ ++ AQ R+ + ++EE +++ R + +
Sbjct: 72 LELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 131
Query: 415 EQQY--EESQTRVNELTVINVNLSSSKA-----KIEQELAIVAADYDEITKELRIADERY 467
E + +E + + E+ + + +A ++ ++L I+ D + + +A+ +
Sbjct: 132 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKC 191
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
++ ELK+ +L + + K + E E+K ++ +L+E E A +R ++KL
Sbjct: 192 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEF-AERSVAKL 250
Query: 528 EARIKDMELELDEEKRRH 545
E I D+E EL +K ++
Sbjct: 251 EKTIDDLEDELYAQKLKY 268
Score = 47.6 bits (108), Expect = 1e-04
Identities = 43/197 (21%), Positives = 96/197 (48%), Gaps = 24/197 (12%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+++E A+ A+ E E + A+ER ++++ EL + L ++ + K K +
Sbjct: 13 KLDKENALDRAEQAEA--EQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQE 70
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+++ + + EA ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 71 KLELAEKKAADAEAE--------VASLNRRIQLVEEELDRAQERLATALQKLEEAEKA-- 120
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------- 613
+E ++ + ++++ K +K+ + + QL E + +++++ + R
Sbjct: 121 -----ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 175
Query: 614 ELEAAEDRADVAESNLS 630
+LE E+RA++AES S
Sbjct: 176 DLERTEERAELAESKCS 192
>AL590431-11|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein.
Length = 284
Score = 66.1 bits (154), Expect = 4e-10
Identities = 56/258 (21%), Positives = 123/258 (47%), Gaps = 14/258 (5%)
Query: 295 NDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKT 354
N + E EQ A E +L+ E+ ++KKL+ TE EL D ++ D Q+
Sbjct: 17 NALDRAEQAEAEQKQAE--ERSKQLEDELAAMQKKLKG--TEDEL--DKYSEALKDAQEK 70
Query: 355 IKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++ + + + + R++Q+ ++ AQ R+ + ++EE +++ R + +
Sbjct: 71 LELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
Query: 415 EQQY--EESQTRVNELTVINVNLSSSKA-----KIEQELAIVAADYDEITKELRIADERY 467
E + +E + + E+ + + +A ++ ++L I+ D + + +A+ +
Sbjct: 131 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKC 190
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
++ ELK+ +L + + K + E E+K ++ +L+E E A +R ++KL
Sbjct: 191 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEF-AERSVAKL 249
Query: 528 EARIKDMELELDEEKRRH 545
E I D+E EL +K ++
Sbjct: 250 EKTIDDLEDELYAQKLKY 267
Score = 47.6 bits (108), Expect = 1e-04
Identities = 43/197 (21%), Positives = 96/197 (48%), Gaps = 24/197 (12%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+++E A+ A+ E E + A+ER ++++ EL + L ++ + K K +
Sbjct: 12 KLDKENALDRAEQAEA--EQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQE 69
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+++ + + EA ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 70 KLELAEKKAADAEAE--------VASLNRRIQLVEEELDRAQERLATALQKLEEAEKA-- 119
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------- 613
+E ++ + ++++ K +K+ + + QL E + +++++ + R
Sbjct: 120 -----ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 174
Query: 614 ELEAAEDRADVAESNLS 630
+LE E+RA++AES S
Sbjct: 175 DLERTEERAELAESKCS 191
>AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory
factor 1 variant protein.
Length = 1096
Score = 66.1 bits (154), Expect = 4e-10
Identities = 100/471 (21%), Positives = 200/471 (42%), Gaps = 35/471 (7%)
Query: 186 LEESRRNVQNERMYKPDFQASRTLVNRDYTNLSK--NVLAKALMESKAMNSCDS--RVTE 241
+EES R+ +PD S T +N T L K A + +A++ + + E
Sbjct: 396 MEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVE 455
Query: 242 SITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQT 301
+ E + RE ++ ++ E ++ ++ N +E+ VK+ + S+ L D Q
Sbjct: 456 FLNEKLEKREAQ----LLSLSKEKALLEEAFDNLKDEMFR-VKE-ESSSISSLKDEFTQR 509
Query: 302 SIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ 361
E E+ + K E+ IK++L ++ E + D+ + + + + + ++ +
Sbjct: 510 IAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETA-DLLKEKDEQI-RGLMEEGEK 567
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L++ Q H + ++L+ + ++ E+EE + +Q L K VE+Q+ E+
Sbjct: 568 LSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHREN 627
Query: 422 QTRVN--------ELTVINVNLSSSKAKIEQELAIVAADYDEIT---KELRIADERYQR- 469
++N +L + V++ + K A + + Y E+T K D Q
Sbjct: 628 IKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEA 687
Query: 470 -VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLE 528
+ E+K E ++ + +++L I+V ++ + L+ E A R L
Sbjct: 688 ALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAA----ARKEDYLR 743
Query: 529 ARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
I +++ L E + R+ E + + R L + Q E Q + S EK + +S
Sbjct: 744 HEIGELQQRLQEAENRNQELSQSVSSTTRPL---LRQIENLQATLGSQTSSWEKLEKNLS 800
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+L E + + +V R R EL A + + ES SL+R ++ F
Sbjct: 801 ---DRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRF 848
Score = 50.4 bits (115), Expect = 2e-05
Identities = 69/377 (18%), Positives = 160/377 (42%), Gaps = 14/377 (3%)
Query: 219 KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNS--YLNQL 276
K+ + LME S +I + +R ++ V ++N ++ ++ +L Q+
Sbjct: 554 KDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQV 613
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+ KE V++ ++ LN ++ ++ +L + E E K +S + + ++T+
Sbjct: 614 LDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYK-ELTD 672
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
L + A K + + + ++ E+ ++ Q + + + + ++
Sbjct: 673 LHKAN--AAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQR 730
Query: 397 VEEIRGNYEQALRVK-RSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQELAIVAADYD 454
E+ E LR + ++Q+ +E++ R EL+ ++ +IE A + +
Sbjct: 731 TEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTS 790
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
K + +R QT L VE E ++ + S+E + N +R E
Sbjct: 791 SWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQ--NSLLRQENSRF 848
Query: 515 NA-IVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKE----RQLKEVIIQCEED 569
A + K + KLE ++EL+ K + T++ RK++ QL+ ++ E++
Sbjct: 849 QAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQE 908
Query: 570 QKNISLLQDSLEKTSQK 586
+K Q+++++ +K
Sbjct: 909 RKKAIFTQETIKEKERK 925
>M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein.
Length = 284
Score = 65.3 bits (152), Expect = 7e-10
Identities = 56/262 (21%), Positives = 124/262 (47%), Gaps = 16/262 (6%)
Query: 299 KQTSIEIEQLNA--RVVEAETKLKSEVTRIKK------KLQIQITELELSLDVANKTNID 350
K +++++ NA R +AE K+ R K+ LQ ++ E LD ++ D
Sbjct: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKD 66
Query: 351 LQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV 410
Q+ ++ + T+ + + R++Q+ ++ AQ R+ + ++EE +++ R
Sbjct: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
Query: 411 KRSVEQ--QYEESQTRVNELTVINVNLSSSKA-----KIEQELAIVAADYDEITKELRIA 463
+ +E Q +E + + E+ + + A ++ ++L I+ +D + + ++
Sbjct: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
Query: 464 DERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI 523
+ + ++ ELK +L + + K + E E+K +S +L+E E A +R
Sbjct: 187 EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF-AERS 245
Query: 524 ISKLEARIKDMELELDEEKRRH 545
++KLE I D+E EL +K ++
Sbjct: 246 VTKLEKSIDDLEDELYAQKLKY 267
Score = 48.4 bits (110), Expect = 8e-05
Identities = 42/205 (20%), Positives = 100/205 (48%), Gaps = 24/205 (11%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+++E A+ A+ E K + A++R ++++ EL + L ++ + K K +
Sbjct: 12 KLDKENALDRAEQAEADK--KAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE 69
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+++ + + EA+ ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 70 KLELAEKKATDAEAD--------VASLNRRIQLVEEELDRAQERLATALQKLEEAEKA-- 119
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------- 613
+E ++ + +++ +K +K+ I + QL E + +++ + + R
Sbjct: 120 -----ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
Query: 614 ELEAAEDRADVAESNLSLIRAKHRT 638
+LE AE+RA+++E + + + +T
Sbjct: 175 DLERAEERAELSEGKCAELEEELKT 199
>AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 65.3 bits (152), Expect = 7e-10
Identities = 50/247 (20%), Positives = 117/247 (47%), Gaps = 12/247 (4%)
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ +K+K+Q+ L+ D A + LQ+ ++ + + + + R++Q+ ++
Sbjct: 7 IEAVKRKIQV----LQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEE 62
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY--EESQTRVNELTVINVNLSSSKA 440
AQ R+ + ++EE +++ R + +E + +E + + E+ + + +A
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Query: 441 -----KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
++ ++L I+ D + + +A+ + ++ ELK+ +L + + K +
Sbjct: 123 DRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKE 182
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
E E+K ++ +L+E E A +R ++KLE I D+E +L K H T ++L +
Sbjct: 183 DKYEEEIKILTDKLKEAETRAEF-AERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQT 241
Query: 556 ERQLKEV 562
L E+
Sbjct: 242 LLDLNEM 248
Score = 49.2 bits (112), Expect = 5e-05
Identities = 69/251 (27%), Positives = 110/251 (43%), Gaps = 30/251 (11%)
Query: 367 THYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN 426
T + V+R++QV Q A+ R + L EVE R EQA + V Q
Sbjct: 5 TTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQA---EAEVASLNRRIQLVEE 61
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDE----ITKELRIADERYQRVQTELKHTVEHLH 482
EL L+++ K+E+ A AAD E + + + DE +Q +H+
Sbjct: 62 ELDRAQERLATALQKLEE--AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIA 119
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM-----ELE 537
EE +R K E V + L I I LE E A + + S+LE +K++ LE
Sbjct: 120 EEADR--KYEEVARKLVI----IEGDLERTEERAELAESK-CSELEEELKNVTNNLKSLE 172
Query: 538 LDEEK-----RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKR 592
EK ++ E IKIL K LKE + E +++++ L+ +++ K+ K
Sbjct: 173 AQAEKYSQKEDKYEEEIKILTDK---LKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKE 229
Query: 593 Q-LAEQEGMSQ 602
+ L Q + Q
Sbjct: 230 EHLCTQRMLDQ 240
Score = 42.7 bits (96), Expect = 0.004
Identities = 35/155 (22%), Positives = 79/155 (50%), Gaps = 15/155 (9%)
Query: 488 IVKIEAVKKSLEI---EVKNISVRLEEVEANAIVGGKRIISKLEARIKDME--LELDEEK 542
I IEAVK+ +++ + + R E ++ + G +R + EA + + ++L EE+
Sbjct: 4 ITTIEAVKRKIQVLQQQADDAEERAERLQRE-VEGERRAREQAEAEVASLNRRIQLVEEE 62
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
A+ + L ++L+E +E ++ + ++++ K +K+ + + QL E + +++
Sbjct: 63 LDRAQ--ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 603 QSVTRVRRFQR-------ELEAAEDRADVAESNLS 630
++ + R +LE E+RA++AES S
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESKCS 155
>AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled coil
protein protein.
Length = 1594
Score = 65.3 bits (152), Expect = 7e-10
Identities = 79/347 (22%), Positives = 173/347 (49%), Gaps = 28/347 (8%)
Query: 279 LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS---EVTRIKKKLQIQIT 335
L+E ++ D+ + ++ ++ E+ + +++E E + S E+ +K+ +I +
Sbjct: 902 LEEVLQNKDNEFALVKHEKEAVICLQNEK-DQKLLEMENIMHSQNCEIKELKQSREIVLE 960
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
+L+ L V N + L + + QSL+ Q+H E++ LQV Q ++ +
Sbjct: 961 DLK-KLHVENDEKLQLLRA-ELQSLE----QSHLKELEDTLQVRHIQE--FEKVMTDHRV 1012
Query: 396 EVEEIRGNYEQAL-RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYD 454
+EE++ +Q + +++ S + +E + ++ EL + +LS ++ K+E ELA+ A+ D
Sbjct: 1013 SLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETD 1072
Query: 455 EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEA 514
EI ++ + + R Q+ +T LK +E E + +I + + ++ +N V L E+
Sbjct: 1073 EI--KILLEESRAQQKET-LKSLLE--QETENLRTEISKLNQKIQDNNENYQVGLAELRT 1127
Query: 515 NAIVGGKRIISKLEARIKD----MELELDEEKRRHAETIKILRKKERQLKEVIIQCEE-- 568
+ + IS+L +R ++ ++ EL++ H + +I E+ LKE II+ +
Sbjct: 1128 LMTIEKDQRISELISRHEEESNILKAELNKVTSLHNQAFEI----EKNLKEQIIELQSKL 1183
Query: 569 DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
D + +L + EK +Q+ Y+ + E Q+ V+ + + +L
Sbjct: 1184 DSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQL 1230
Score = 54.4 bits (125), Expect = 1e-06
Identities = 63/332 (18%), Positives = 152/332 (45%), Gaps = 18/332 (5%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
+ + + I +E L VE + KL+ ++ Q + ELE +L V + + +K
Sbjct: 948 IKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQ--EFEK 1005
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVT-LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
+ + L E++ ++ Q+Q + + ++++Q L +V ++ R K
Sbjct: 1006 VMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDT-----RCKL 1060
Query: 413 SVEQQYEESQTRVNELTVINVNLSSS---KAKIEQELAIVAADYDEITKELRIADERYQR 469
VE +E++T ++ + K+ +EQE + + ++ ++++ +E YQ
Sbjct: 1061 EVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQV 1120
Query: 470 VQTELKH--TVEHLHEEQERIVKIEAVKKSLEIEVKNISV---RLEEVEANAIVGGKRII 524
EL+ T+E E I + E L+ E+ ++ + E+E N +
Sbjct: 1121 GLAELRTLMTIEKDQRISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQ 1180
Query: 525 SKLEARIKDMELELDEEKRRHAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
SKL++ + +E + DE+ + E + I++ E+ ++++ E+D++ + + + + EK
Sbjct: 1181 SKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQL-IQKLNCEKD 1239
Query: 584 SQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ K E+E + ++ + +V+ + ++
Sbjct: 1240 EAIQTALKEFKLEREVVEKELLEKVKHLENQI 1271
Score = 45.6 bits (103), Expect = 6e-04
Identities = 92/470 (19%), Positives = 203/470 (43%), Gaps = 51/470 (10%)
Query: 183 QTLLE-ESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTE 241
Q LLE E+ + QN + + + SR +V D L K + + S + +
Sbjct: 932 QKLLEMENIMHSQNCEI--KELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLK 989
Query: 242 SITETVRVRETSPTTCVV---RINTE-LPAIDNSYLNQLNE-----LKETVKQFDDLSVY 292
+ +T++VR V+ R++ E L + +NQ+ E ++E KQ +L +
Sbjct: 990 ELEDTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLK 1049
Query: 293 ILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQIT---ELELSLDVANKTNI 349
+ + S + +E+E E K+ E +R ++K ++ E E +K N
Sbjct: 1050 VSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQ 1109
Query: 350 DLQKTIKKQSLQLTEIQTHYD-EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL 408
+Q + + L E++T E +++ + ++ + L E+ ++ + QA
Sbjct: 1110 KIQDNNENYQVGLAELRTLMTIEKDQRISELISRH---EEESNILKAELNKVTSLHNQAF 1166
Query: 409 RVKRSVEQQYEESQTRVN-ELTVIN------------------VNLSSSKAKI------- 442
+++++++Q E Q++++ EL+ + NL + K+
Sbjct: 1167 EIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQD 1226
Query: 443 -EQELAIVAADYDE-ITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
EQ + + + DE I L+ + V+ EL V+HL + + I++ +
Sbjct: 1227 REQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSS 1286
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
V + +L+E +A + + + ++++ L E++ + T+ + R+K R K
Sbjct: 1287 LVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTV-LTREKMR--K 1343
Query: 561 EVIIQCEEDQKNISLLQDSLEK-TSQKVSIYKRQLAEQEGMSQQSVTRVR 609
E II D+ ++ Q +K + +S + +L E++ ++ V+++R
Sbjct: 1344 ENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLR 1393
>M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein.
Length = 264
Score = 64.9 bits (151), Expect = 9e-10
Identities = 55/250 (22%), Positives = 122/250 (48%), Gaps = 13/250 (5%)
Query: 304 EIEQLNARVVEAETK-LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQL 362
E + + + E +K L+ E+ ++KKL+ TE EL D ++ D Q+ ++ +
Sbjct: 3 EQAEADKKAAEDRSKQLEDELVSLQKKLKG--TEDEL--DKYSEALKDAQEKLELAEKKA 58
Query: 363 TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ--QYEE 420
T+ + + R++Q+ ++ AQ R+ + ++EE +++ R + +E Q +E
Sbjct: 59 TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDE 118
Query: 421 SQTRVNELTVINVNLSSSKA-----KIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
+ + E+ + + A ++ ++L I+ +D + + +++ + ++ ELK
Sbjct: 119 EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELK 178
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
+L + + K + E E+K +S +L+E E A +R ++KLE I D+E
Sbjct: 179 TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF-AERSVTKLEKSIDDLE 237
Query: 536 LELDEEKRRH 545
EL +K ++
Sbjct: 238 DELYAQKLKY 247
Score = 45.6 bits (103), Expect = 6e-04
Identities = 36/186 (19%), Positives = 88/186 (47%), Gaps = 20/186 (10%)
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-- 523
R ++ + + K + + ++ +V ++ K E E+ S L++ + + K+
Sbjct: 1 RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATD 60
Query: 524 ----ISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDS 579
++ L RI+ +E ELD + R A ++ L + E+ +E ++ + +++
Sbjct: 61 AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA-------ADESERGMKVIESR 113
Query: 580 LEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR-------ELEAAEDRADVAESNLSLI 632
+K +K+ I + QL E + +++ + + R +LE AE+RA+++E + +
Sbjct: 114 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 173
Query: 633 RAKHRT 638
+ +T
Sbjct: 174 EEELKT 179
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 64.5 bits (150), Expect = 1e-09
Identities = 110/522 (21%), Positives = 216/522 (41%), Gaps = 53/522 (10%)
Query: 164 SELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLA 223
+ELRQ+ K K + L +E N+ E K + L+ T +N+
Sbjct: 2400 AELRQQ----HDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQ 2455
Query: 224 KALMES--KAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKE 281
KA ++S K+M+S + + + ++ E + I E + + N+LKE
Sbjct: 2456 KAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH-----LSIILEKDQLIQEAAAENNKLKE 2510
Query: 282 TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSL 341
++ L + E +L+A +++ L +T IK Q Q+ E++L
Sbjct: 2511 EIRG--------LRSHMDDLNSENAKLDAELIQYREDLNQVIT-IKDSQQKQLLEVQL-- 2559
Query: 342 DVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
+ N +L+ K +L E + ++++R ++ + I+SL + ++
Sbjct: 2560 ----QQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT 2615
Query: 402 GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK---AKIEQELAIVAADYDEITK 458
AL+ + ++ + + + + E+ ++ SSS+ A++E+EL V E K
Sbjct: 2616 RQVT-ALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK---EAAK 2671
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVK--IEAVKKSLEIEVKNISVRLEEVEANA 516
++ +++ ++ L H + E E + E + +E+E K + V E A
Sbjct: 2672 KVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTA 2731
Query: 517 -IVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL----------RKKERQLKEVIIQ 565
I R +S L+ ELDE KR++ ++K L R+++ L E
Sbjct: 2732 QIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFS 2791
Query: 566 CEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVA 625
++N SL LEK +Q++ QL + S +V+ F + + + ++ D
Sbjct: 2792 MNSTEEN-SL--SHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHL 2848
Query: 626 ESNLSLIR----AKHRTFVTTSTVPGSQVYLVQESRALSSER 663
+ L R K R+ ST P L + +L ++R
Sbjct: 2849 WNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDR 2890
Score = 62.9 bits (146), Expect = 3e-09
Identities = 95/450 (21%), Positives = 197/450 (43%), Gaps = 25/450 (5%)
Query: 148 EIEK-ELDLYEKEVNL--GSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
E+E+ + + E E+N E+ +K + K + Q L+EE ++N N
Sbjct: 685 ELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQ-LIEEFKKNADNNSSAFTALS 743
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESIT-ETVRVRETSPTTCVVRINT 263
R + LS +A ++ MN ++ + E+ + T + ++
Sbjct: 744 EERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSI 803
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNA--RVVEAETKLKS 321
E + D NEL + QF + S I + S+ + E E L RV +K++
Sbjct: 804 EAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVE- 862
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNID-LQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
E+++ + +++IT+++ L + K +++ LQ+TI+++ Q+TEI E QL
Sbjct: 863 ELSQALSQKELEITKMDQLL-LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 921
Query: 381 DQYGVAQRRIQ---SLTGEVEEI-RGNYEQALRVKRSVEQQYEE----SQTRVNELTVIN 432
GV + ++ +L EE + E+ V ++Q Y+E Q EL
Sbjct: 922 FSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEF 981
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
L + +++L + E+ + + +E ++ E K + E ER ++E
Sbjct: 982 DLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIP--LSETER-GEVE 1038
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
K++ E K ++ + +E+E + K+ IS+ E ++ + +L+E+ + ++
Sbjct: 1039 EDKENKEYSEKCVTSKCQEIE----IYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALV 1094
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
++ + L++ Q + Q IS Q ++K
Sbjct: 1095 KQMNQTLQDKTNQIDLLQAEISENQAIIQK 1124
Score = 58.8 bits (136), Expect = 6e-08
Identities = 118/554 (21%), Positives = 227/554 (40%), Gaps = 39/554 (7%)
Query: 142 QKKRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
QK ++++ D KE N+G +LRQ R + T +ES + + +
Sbjct: 1208 QKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPG--LEE 1265
Query: 201 PDFQASRTLVNRDY--TNL-----SKNVLAKALMESKAMNSCDSRVTESITETVRV--RE 251
P F+A+ + +NL S + A AL ++ +++ E E V + +
Sbjct: 1266 PLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKV 1325
Query: 252 TSPTTCVVRINTELPAIDNSYLNQLNELK--ETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
+S T+ + + + E+ + Q E++ +TV ++ L + + ++I L
Sbjct: 1326 SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE 1385
Query: 310 ARVVEAETKLKSEVTRIKKK------LQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
+ E + KL I KK L Q++E E +L I+ + IK QL
Sbjct: 1386 -HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLE 1444
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+DE +QLQV L + I + ++I+ + AL ++ ++ + Q
Sbjct: 1445 MQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQE 1504
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
++ L+ S A +E +++ + D + L + E ++ TE+ + L E
Sbjct: 1505 ELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRS---LLE 1561
Query: 484 EQERIVKIEAVKKSLE--IEVKNISVR-LEEVEANAIVGGKRIISKLEARIKDMELELD- 539
Q E++K +LE E K V+ +E ++++ I K + K+ E+ L
Sbjct: 1562 NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQS 1621
Query: 540 -EEKRRHAETIKILRKKERQLK-EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
E AE I+ + + RQ K E+ + + N + L++ Q++ K ++ +
Sbjct: 1622 YENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKF 1681
Query: 598 EGMSQQSVTRVR----RFQRELEAAEDRA-----DVAESNLSLIRAKHRTFVTTSTVPGS 648
QQ + + R + E+ A D A + SN S+ R + T+
Sbjct: 1682 AKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKK 1741
Query: 649 QVYLVQESRALSSE 662
L+ E +LS E
Sbjct: 1742 FQSLMSEKDSLSEE 1755
Score = 54.4 bits (125), Expect = 1e-06
Identities = 64/348 (18%), Positives = 156/348 (44%), Gaps = 15/348 (4%)
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L+ E +++KKLQ +T + L A + L++ +K+Q +Q +DE ++ +
Sbjct: 1169 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENEN 1228
Query: 379 TLDQYGVAQRRI-QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
DQ Q ++ +S+ G++ + +++ +E+ ++ + + V+ NL
Sbjct: 1229 IGDQLRQLQIQVRESIDGKLPST--DQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCP 1286
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK--HTVEHLHEEQERIVKIEAVK 495
++ + + + ++ + ++V+ ELK T L ++ E + +++
Sbjct: 1287 DWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQI 1346
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
+E++++ E E +A +++ S + +I +E L E + + E K++ KK
Sbjct: 1347 NKQGLEIESLKTVSHEAEVHAESLQQKLESS-QLQIAGLE-HLRELQPKLDELQKLISKK 1404
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
E + + Q E + ++ +Q + + + QL E +++ R+++ Q EL
Sbjct: 1405 EEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQL---EMQAKEHDERIKQLQVEL 1461
Query: 616 -EAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSE 662
E + ++ E + RAK + S+ ++E+++L E
Sbjct: 1462 CEMKQKPEEIGEES----RAKQQIQRKLQAALISRKEALKENKSLQEE 1505
Score = 50.4 bits (115), Expect = 2e-05
Identities = 60/314 (19%), Positives = 143/314 (45%), Gaps = 15/314 (4%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL+SE+ K L+ Q+T+L SL+ + +L+ I++Q + + Y++++ LQ
Sbjct: 2309 KLESEL----KSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ 2364
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+ + I ++ + E+A++V ++ + ++ + EL +
Sbjct: 2365 ASRELTSRLHEEINMKEQKIISLLSGKEEAIQV--AIAELRQQHDKEIKELENLLSQEEE 2422
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+E+E +++ + L+ + + + +L V+ + Q +I V
Sbjct: 2423 ENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRI--VGDY 2480
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
++E +++S+ LE+ + + +KL+ I+ + +D+ +A+ L +
Sbjct: 2481 QQLEERHLSIILEKDQLIQEAAAEN--NKLKEEIRGLRSHMDDLNSENAKLDAELIQYRE 2538
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
L +VI + QK LL+ L++ + + Y + L E+ S+++ +RR L+
Sbjct: 2539 DLNQVITIKDSQQK--QLLEVQLQQNKELENKYAK-LEEKLKESEEANEDLRRSFNALQ- 2594
Query: 618 AEDRADVAESNLSL 631
E++ D+++ SL
Sbjct: 2595 -EEKQDLSKEIESL 2607
Score = 50.0 bits (114), Expect = 3e-05
Identities = 50/217 (23%), Positives = 97/217 (44%), Gaps = 11/217 (5%)
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQE 486
+LT +N + KA+ L ++++K + + E ++ ++KH L E++E
Sbjct: 103 KLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIE-KIKHK---LQEKEE 158
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
I ++A + E S E V K+ + + E I ++ +L + + A
Sbjct: 159 LISTLQAQLTQAQAEQPAQS----STEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQA 214
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE-KTSQKVSIYKRQLAEQEGMSQQSV 605
+++R+K+ + E ++ ED+ + Q +E + QK+ + +R+L E E
Sbjct: 215 AQ-QVVREKDARF-ETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRA 272
Query: 606 TRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTT 642
V Q+EL AAE R + L + A+H T T
Sbjct: 273 QVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 309
Score = 50.0 bits (114), Expect = 3e-05
Identities = 98/496 (19%), Positives = 194/496 (39%), Gaps = 34/496 (6%)
Query: 150 EKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQA-SRT 208
+K L+L E+ L +E+ G +AK +TLL + + K +++ S+
Sbjct: 1687 QKILELEEENDRLRAEVHPA-----GDTAKECMETLLSSNASMKEELERVKMEYETLSKK 1741
Query: 209 LVN--RDYTNLSKNVL-AKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTEL 265
+ + +LS+ V K +E + TE V E + I E
Sbjct: 1742 FQSLMSEKDSLSEEVQDLKHQIEDNVSKQANLEATEKHDNQTNVTEEGTQS----IPGET 1797
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI-----EIEQLNARVVEAETKLK 320
D+ ++ E+V + + D S I +I+QL R+ E + K
Sbjct: 1798 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEE-K 1856
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+ + L+ + L + + LQ+ + K +L +IQ V + +
Sbjct: 1857 QKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1916
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQAL---RVKRS-VEQQYEESQTRVNELTVINVNLS 436
++ + R+ + E+ GNY Q + ++K +E + + + V+EL L
Sbjct: 1917 EEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLV 1976
Query: 437 SSKAKIEQEL------AIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQERIV 489
K K+E E+ I A + K + E + Q E+K + QE+I
Sbjct: 1977 KEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKIS 2036
Query: 490 KIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETI 549
+E K+LE V+ S + E+ + K +A + ++ LD+ + A +
Sbjct: 2037 ALERTVKALEF-VQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVL 2095
Query: 550 --KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
+ KKE Q + ++ + QK+ L+ LE+ +K K+ + E+ ++
Sbjct: 2096 ADNLKLKKELQSNKESVKSQMKQKDED-LERRLEQAEEKHLKEKKNMQEKLDALRREKVH 2154
Query: 608 VRRFQRELEAAEDRAD 623
+ E++ ++ D
Sbjct: 2155 LEETIGEIQVTLNKKD 2170
Score = 48.8 bits (111), Expect = 6e-05
Identities = 93/510 (18%), Positives = 219/510 (42%), Gaps = 35/510 (6%)
Query: 143 KKRMQEIEKELD-LYEKEVNLGSELRQK-AAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
KK + E+E+E L +++ + SE+R++ +G + ++ +E + ++ ++
Sbjct: 1962 KKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEV 2021
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVT-ESITETVRVRETSPTTCVV 259
Q + L + V A +++++ D +T E++ + V R+ +
Sbjct: 2022 KQLQKDCIRYQEKISALERTVKALEFVQTESQK--DLEITKENLAQAVEHRKKAQA---- 2075
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
+ + +D++ L + +K +L + S+ + E L R+ +AE K
Sbjct: 2076 ELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKD-EDLERRLEQAEEKH 2134
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
E KK +Q ++ L +T ++Q T+ K+ ++ ++Q + D QL
Sbjct: 2135 LKE----KKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAF 2190
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES----QTRVNELTVINVNL 435
Q + E ++ + A++ K + E++ + ++ ++++ L
Sbjct: 2191 TKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2250
Query: 436 SSSKAKIEQELAIVAADYD-EITKELRIADE---RYQRVQTELKHTVEHLHEEQERIVKI 491
+ +++E + I + E+ + ++ D + + ++L+ T H Q + K+
Sbjct: 2251 KINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKL 2310
Query: 492 EAVKKSLEIEVKNISVRLEEV-EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK 550
E+ KSL+ ++ ++S LE+ E + G II + EA I++ + ++ + ++
Sbjct: 2311 ESELKSLKDQLTDLSNSLEKCKEQKGNLEG--IIRQQEADIQNSKFSYEQLE----TDLQ 2364
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ----LAEQEGMSQQSVT 606
R+ +L E I ++QK ISLL E ++ ++Q + E E + Q
Sbjct: 2365 ASRELTSRLHEEINM--KEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEE 2422
Query: 607 RVRRFQRELEAAEDRADVAESNLSLIRAKH 636
+ E + A D+ + L I+ ++
Sbjct: 2423 ENIVLEEENKKAVDKTNQLMETLKTIKKEN 2452
Score = 46.8 bits (106), Expect = 2e-04
Identities = 86/484 (17%), Positives = 213/484 (44%), Gaps = 44/484 (9%)
Query: 144 KRMQEIEKEL-DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+R+++++ EL ++ +K +G E R K + R A I++ + +++Q E
Sbjct: 1452 ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEE------ 1505
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
+R + R L K+L + ++ S ++ +++ + + + + ++
Sbjct: 1506 LSLARGTIER---------LTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD 1556
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
L ++N L+ E++K L++ L + ++ EIE L + + T+ + +
Sbjct: 1557 RSL--LENQ---SLSSSCESLK----LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEK 1607
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
++K+ +I + E +V+N+ +Q ++ + E+ + + T Q
Sbjct: 1608 HKELQKEYEILLQSYE---NVSNEAE-RIQHVVEAVRQEKQELYGKLRSTEANKKETEKQ 1663
Query: 383 YGVAQRRIQSLTGEVEEI-RGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
A++ ++ + ++ + + ++ L ++ ++ E + L SS A
Sbjct: 1664 LQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNAS 1723
Query: 442 IEQELAIVAADYDEITKELRI----ADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+++EL V +Y+ ++K+ + D + VQ +LKH +E +Q + E
Sbjct: 1724 MKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQ-DLKHQIEDNVSKQANLEATEKHDNQ 1782
Query: 498 LEI-EVKNISVRLEEVEANAI-VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
+ E S+ E E +++ + + S+ K + ++ H E L++
Sbjct: 1783 TNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQI 1842
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG---MSQQSVTRVRRFQ 612
+ QLKE I EE+++ +LE ++K ++ Q++ ++G M Q+ VT++
Sbjct: 1843 D-QLKERIAGLEEEKQKNKEFSQTLE--NEKNTLLS-QISTKDGELKMLQEEVTKMNLLN 1898
Query: 613 RELE 616
++++
Sbjct: 1899 QQIQ 1902
Score = 44.8 bits (101), Expect = 0.001
Identities = 75/396 (18%), Positives = 177/396 (44%), Gaps = 51/396 (12%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELE-LSLDVANK-TNID-LQKTIKKQSL 360
+++QL + EAE + + + + ++ LS++ +K I+ LQ + L
Sbjct: 765 QVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQL 824
Query: 361 QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-----------LR 409
Q +E T +Q QLQ + R++ ++ +VEE+ Q L
Sbjct: 825 QFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLE 884
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRI---ADE- 465
KR VE + + + ++T I+ +++ ++ +E + + + ++L + A+E
Sbjct: 885 KKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEA 944
Query: 466 RYQRVQ--TELKHTVEHLHEEQERIVKI--EAVKKSLEIEVKNISVRLEEVEANAIVGGK 521
+ ++V+ E+ ++ ++E +I E ++ ++ K R +++A A++ K
Sbjct: 945 KKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQA-ALINRK 1003
Query: 522 RIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
++ ++ +R+++ L +E ++ L + ER + EED++N + +
Sbjct: 1004 ELLQRV-SRLEEELANLKDESKKEIP----LSETERG------EVEEDKENKEYSEKCVT 1052
Query: 582 KTSQKVSIYKRQ---------------LAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
Q++ IY +Q L E+ +Q V++ + L+ ++ D+ +
Sbjct: 1053 SKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQ 1112
Query: 627 SNLSLIRAKHRTFVTTST--VPGSQVYLVQESRALS 660
+ +S +A + +T++T G V LV+E+ +S
Sbjct: 1113 AEISENQAIIQKLITSNTDASDGDSVALVKETVVIS 1148
Score = 43.6 bits (98), Expect = 0.002
Identities = 88/467 (18%), Positives = 200/467 (42%), Gaps = 40/467 (8%)
Query: 220 NVLAKALMESKA-MNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNE 278
N + K + +KA + S + + E + V T P + +L D S + E
Sbjct: 91 NKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQS-----EEQLSKHDKSSTEEEME 145
Query: 279 LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELE 338
+++ + + I ++ T + EQ E E + + +K+ I + +
Sbjct: 146 IEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQ 205
Query: 339 LSLDVANKTNIDLQKTIKKQSLQL-TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEV 397
LS A + Q+ ++++ + T+++ H DE+ QL D Q++++ L ++
Sbjct: 206 LSQTQAEQA---AQQVVREKDARFETQVRLHEDELL-QLVTQADVETEMQQKLRVLQRKL 261
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE-- 455
EE + +V ++Q+ ++ R N+ +++ L +A+ V + +E
Sbjct: 262 EEHEESLVGRAQVVDLLQQELTAAEQR-NQ--ILSQQLQQMEAEHNTLRNTVETEREESK 318
Query: 456 --ITK-ELRIADER--YQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLE 510
+ K EL +A+ + + +Q E+ H +E + + ++E+ +LE + K +E
Sbjct: 319 ILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHK---AEME 375
Query: 511 EVEANAIV---GGKRIISKLEARIKDMELELDEEKRRHA-ETIKILRKKERQLKEVIIQC 566
E ++ + G+ + S +A +KD +L ++K A ++ + +++ E QL++ +
Sbjct: 376 EKTSHILSLQKTGQELQSACDA-LKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEI 434
Query: 567 EEDQKNISLLQDSLEKTSQKVSIYKR--QLAEQEGMS--QQSVTRVRRFQR-------EL 615
+ + L Q + +Y Q +E ++ Q+ V + + EL
Sbjct: 435 SQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIEL 494
Query: 616 EAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSE 662
E + + S ++L+ A++RT V + + R+ S+E
Sbjct: 495 EELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAE 541
Score = 39.1 bits (87), Expect = 0.049
Identities = 68/348 (19%), Positives = 153/348 (43%), Gaps = 25/348 (7%)
Query: 286 FDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVAN 345
+++L + ++ KQ S + V++ K S + + +L ++ L+ N
Sbjct: 2849 WNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQIN 2908
Query: 346 KTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL-QVTLD-QYGVAQRRIQSLTGEVEEIRGN 403
+ +L +K Q + + + +Q +L Q L Q+ + Q R++ + E+ E R
Sbjct: 2909 QEITELHP-LKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMK 2967
Query: 404 YEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA 463
EQ L +QQ Q + EL + K + +++ + + + ++ L
Sbjct: 2968 -EQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYE 3026
Query: 464 DERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRL----EEVEANAIVG 519
E ++T+L +++ +H+++ RI ++ + L E +S++L + + N
Sbjct: 3027 TEL---LRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHY 3083
Query: 520 GKRI--ISKLEARIKDME---LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
G + + LE ++++++ L +D E + RK + + + E Q++ S
Sbjct: 3084 GDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPE------ELREPQQSFS 3137
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQ--EGMSQQSVTRVRRFQ-RELEAAE 619
Q L T Q+V+ ++ L E+ + ++ ++ V Q R LE +E
Sbjct: 3138 EAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRLEHSE 3185
>D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein.
Length = 709
Score = 64.5 bits (150), Expect = 1e-09
Identities = 75/350 (21%), Positives = 160/350 (45%), Gaps = 21/350 (6%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S + S+E+ A++ +L+ + ++ Q ++ ++E+ L + N++L
Sbjct: 169 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQ-ELEQMEIELKRLQQENMNLLSDA 227
Query: 356 KKQSLQLTEIQTHYDEVQR--QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ + E+ ++ R +L+ + +Y I+ VEE++ + + L K
Sbjct: 228 RSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTM 287
Query: 414 VEQQYEESQTR---VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
+E Q E ++ R ++EL N+ L + +E E + +E+ +E + ++
Sbjct: 288 LEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 347
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI-SVRLEEVEANAIVGGKRIISKLEA 529
E H L + EA +KSL EV + S RL ++E + + +L
Sbjct: 348 MDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-QSLTKTVEELRT 406
Query: 530 RIKDME------LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ +E L++++E +R ++ ++IL + Q K+ + C+ K++ + LEKT
Sbjct: 407 TVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKT 466
Query: 584 SQKV---SIYKRQLAEQEGMS-QQSVTRVRRFQRELEAAEDRA-DVAESN 628
+ + S + ++ EQE Q+V+ +R QR +AE R D+ + N
Sbjct: 467 IETLRENSERQIKILEQENEHLNQTVSSLR--QRSQISAEARVKDIEKEN 514
Score = 62.5 bits (145), Expect = 5e-09
Identities = 104/506 (20%), Positives = 226/506 (44%), Gaps = 45/506 (8%)
Query: 143 KKRMQEIEKELD-LYEKEVNLGSELRQKAAMYRGK----SAKAIAQTLLEESRRNVQNER 197
K+ ++++E EL L ++ +NL S+ R A MYR + KA+ LE S + ER
Sbjct: 203 KQELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLE-SEVSRYKER 260
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
++ +F +R L ++ + L+E+K M T + ++ + E
Sbjct: 261 LHDIEFYKARV------EELKED--NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQL 312
Query: 258 VVRINT-ELPA-IDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA 315
+++ E+ +D + +L E T++ S+ D S E+EQ++ +
Sbjct: 313 KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSM----DESLHLGWELEQISRTSELS 368
Query: 316 ETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR- 374
E KS + + ++ +LE+ KT +L+ T+ ++I E QR
Sbjct: 369 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 428
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+V + + + Q + QSL + ++ ++++++E E S+ ++ L N +
Sbjct: 429 SKKVEILENEIVQEK-QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEH 487
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L+ + + + Q +I+ E R+ D ++ E K E + E ++ KIE
Sbjct: 488 LNQTVSSLRQR--------SQISAEARVKD-----IEKENKILHESIKETSSKLSKIEFE 534
Query: 495 KKSLEIEV---KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
K+ ++ E+ K R EE+E N + ++ L+ +I ++++ ++ + E +
Sbjct: 535 KRQIKKELEHYKEKGERAEELE-NELHHLEKENELLQKKITNLKITCEKIEALEQENSE- 592
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
L ++ R+LK+ + + KN++ +SLEK + ++ +L + + ++ +
Sbjct: 593 LERENRKLKKTL----DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 648
Query: 612 QRELEAAEDRADVAESNLSLIRAKHR 637
Q E + E + + L L++A +
Sbjct: 649 QLENKELESEKEQLKKGLELLKASFK 674
Score = 39.5 bits (88), Expect = 0.037
Identities = 45/244 (18%), Positives = 111/244 (45%), Gaps = 15/244 (6%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARV-VEAETKLKSEVTRIKKKLQIQ 333
QL + ET+++ + + IL ++ + + L R + AE ++K ++ + K L
Sbjct: 462 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVK-DIEKENKILHES 520
Query: 334 ITELELSLDVANKTNIDLQKT-IKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS 392
I E L + I+ +K IKK+ E +E++ +L + + Q++I +
Sbjct: 521 IKETSSKL-----SKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITN 575
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
L E+I ++ ++R ++ +++ LT +L +++++E + +
Sbjct: 576 LKITCEKIEALEQENSELERE-NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRN 634
Query: 453 YDEIT------KELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNIS 506
+ + +L++ ++ + + +LK +E L ++ ++E + L+IE + +
Sbjct: 635 VESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ 694
Query: 507 VRLE 510
LE
Sbjct: 695 KTLE 698
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
Length = 3225
Score = 64.5 bits (150), Expect = 1e-09
Identities = 110/522 (21%), Positives = 216/522 (41%), Gaps = 53/522 (10%)
Query: 164 SELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLA 223
+ELRQ+ K K + L +E N+ E K + L+ T +N+
Sbjct: 2366 AELRQQ----HDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQ 2421
Query: 224 KALMES--KAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKE 281
KA ++S K+M+S + + + ++ E + I E + + N+LKE
Sbjct: 2422 KAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH-----LSIILEKDQLIQEAAAENNKLKE 2476
Query: 282 TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSL 341
++ L + E +L+A +++ L +T IK Q Q+ E++L
Sbjct: 2477 EIRG--------LRSHMDDLNSENAKLDAELIQYREDLNQVIT-IKDSQQKQLLEVQL-- 2525
Query: 342 DVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
+ N +L+ K +L E + ++++R ++ + I+SL + ++
Sbjct: 2526 ----QQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT 2581
Query: 402 GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK---AKIEQELAIVAADYDEITK 458
AL+ + ++ + + + + E+ ++ SSS+ A++E+EL V E K
Sbjct: 2582 RQVT-ALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK---EAAK 2637
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVK--IEAVKKSLEIEVKNISVRLEEVEANA 516
++ +++ ++ L H + E E + E + +E+E K + V E A
Sbjct: 2638 KVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTA 2697
Query: 517 -IVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL----------RKKERQLKEVIIQ 565
I R +S L+ ELDE KR++ ++K L R+++ L E
Sbjct: 2698 QIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFS 2757
Query: 566 CEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVA 625
++N SL LEK +Q++ QL + S +V+ F + + + ++ D
Sbjct: 2758 MNSTEEN-SL--SHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHL 2814
Query: 626 ESNLSLIR----AKHRTFVTTSTVPGSQVYLVQESRALSSER 663
+ L R K R+ ST P L + +L ++R
Sbjct: 2815 WNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDR 2856
Score = 62.9 bits (146), Expect = 3e-09
Identities = 95/450 (21%), Positives = 197/450 (43%), Gaps = 25/450 (5%)
Query: 148 EIEK-ELDLYEKEVNL--GSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
E+E+ + + E E+N E+ +K + K + Q L+EE ++N N
Sbjct: 651 ELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQ-LIEEFKKNADNNSSAFTALS 709
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESIT-ETVRVRETSPTTCVVRINT 263
R + LS +A ++ MN ++ + E+ + T + ++
Sbjct: 710 EERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSI 769
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNA--RVVEAETKLKS 321
E + D NEL + QF + S I + S+ + E E L RV +K++
Sbjct: 770 EAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVE- 828
Query: 322 EVTRIKKKLQIQITELELSLDVANKTNID-LQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
E+++ + +++IT+++ L + K +++ LQ+TI+++ Q+TEI E QL
Sbjct: 829 ELSQALSQKELEITKMDQLL-LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 887
Query: 381 DQYGVAQRRIQ---SLTGEVEEI-RGNYEQALRVKRSVEQQYEE----SQTRVNELTVIN 432
GV + ++ +L EE + E+ V ++Q Y+E Q EL
Sbjct: 888 FSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEF 947
Query: 433 VNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
L + +++L + E+ + + +E ++ E K + E ER ++E
Sbjct: 948 DLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIP--LSETER-GEVE 1004
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
K++ E K ++ + +E+E + K+ IS+ E ++ + +L+E+ + ++
Sbjct: 1005 EDKENKEYSEKCVTSKCQEIE----IYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALV 1060
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEK 582
++ + L++ Q + Q IS Q ++K
Sbjct: 1061 KQMNQTLQDKTNQIDLLQAEISENQAIIQK 1090
Score = 58.8 bits (136), Expect = 6e-08
Identities = 118/554 (21%), Positives = 227/554 (40%), Gaps = 39/554 (7%)
Query: 142 QKKRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
QK ++++ D KE N+G +LRQ R + T +ES + + +
Sbjct: 1174 QKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPG--LEE 1231
Query: 201 PDFQASRTLVNRDY--TNL-----SKNVLAKALMESKAMNSCDSRVTESITETVRV--RE 251
P F+A+ + +NL S + A AL ++ +++ E E V + +
Sbjct: 1232 PLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKV 1291
Query: 252 TSPTTCVVRINTELPAIDNSYLNQLNELK--ETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
+S T+ + + + E+ + Q E++ +TV ++ L + + ++I L
Sbjct: 1292 SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE 1351
Query: 310 ARVVEAETKLKSEVTRIKKK------LQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
+ E + KL I KK L Q++E E +L I+ + IK QL
Sbjct: 1352 -HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLE 1410
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
+DE +QLQV L + I + ++I+ + AL ++ ++ + Q
Sbjct: 1411 MQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQE 1470
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHE 483
++ L+ S A +E +++ + D + L + E ++ TE+ + L E
Sbjct: 1471 ELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRS---LLE 1527
Query: 484 EQERIVKIEAVKKSLE--IEVKNISVR-LEEVEANAIVGGKRIISKLEARIKDMELELD- 539
Q E++K +LE E K V+ +E ++++ I K + K+ E+ L
Sbjct: 1528 NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQS 1587
Query: 540 -EEKRRHAETIKILRKKERQLK-EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
E AE I+ + + RQ K E+ + + N + L++ Q++ K ++ +
Sbjct: 1588 YENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKF 1647
Query: 598 EGMSQQSVTRVR----RFQRELEAAEDRA-----DVAESNLSLIRAKHRTFVTTSTVPGS 648
QQ + + R + E+ A D A + SN S+ R + T+
Sbjct: 1648 AKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKK 1707
Query: 649 QVYLVQESRALSSE 662
L+ E +LS E
Sbjct: 1708 FQSLMSEKDSLSEE 1721
Score = 54.4 bits (125), Expect = 1e-06
Identities = 64/348 (18%), Positives = 156/348 (44%), Gaps = 15/348 (4%)
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L+ E +++KKLQ +T + L A + L++ +K+Q +Q +DE ++ +
Sbjct: 1135 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENEN 1194
Query: 379 TLDQYGVAQRRI-QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
DQ Q ++ +S+ G++ + +++ +E+ ++ + + V+ NL
Sbjct: 1195 IGDQLRQLQIQVRESIDGKLPST--DQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCP 1252
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK--HTVEHLHEEQERIVKIEAVK 495
++ + + + ++ + ++V+ ELK T L ++ E + +++
Sbjct: 1253 DWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQI 1312
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
+E++++ E E +A +++ S + +I +E L E + + E K++ KK
Sbjct: 1313 NKQGLEIESLKTVSHEAEVHAESLQQKLESS-QLQIAGLE-HLRELQPKLDELQKLISKK 1370
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
E + + Q E + ++ +Q + + + QL E +++ R+++ Q EL
Sbjct: 1371 EEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQL---EMQAKEHDERIKQLQVEL 1427
Query: 616 -EAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSE 662
E + ++ E + RAK + S+ ++E+++L E
Sbjct: 1428 CEMKQKPEEIGEES----RAKQQIQRKLQAALISRKEALKENKSLQEE 1471
Score = 50.4 bits (115), Expect = 2e-05
Identities = 60/314 (19%), Positives = 143/314 (45%), Gaps = 15/314 (4%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL+SE+ K L+ Q+T+L SL+ + +L+ I++Q + + Y++++ LQ
Sbjct: 2275 KLESEL----KSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ 2330
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+ + I ++ + E+A++V ++ + ++ + EL +
Sbjct: 2331 ASRELTSRLHEEINMKEQKIISLLSGKEEAIQV--AIAELRQQHDKEIKELENLLSQEEE 2388
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+E+E +++ + L+ + + + +L V+ + Q +I V
Sbjct: 2389 ENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRI--VGDY 2446
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
++E +++S+ LE+ + + +KL+ I+ + +D+ +A+ L +
Sbjct: 2447 QQLEERHLSIILEKDQLIQEAAAEN--NKLKEEIRGLRSHMDDLNSENAKLDAELIQYRE 2504
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
L +VI + QK LL+ L++ + + Y + L E+ S+++ +RR L+
Sbjct: 2505 DLNQVITIKDSQQK--QLLEVQLQQNKELENKYAK-LEEKLKESEEANEDLRRSFNALQ- 2560
Query: 618 AEDRADVAESNLSL 631
E++ D+++ SL
Sbjct: 2561 -EEKQDLSKEIESL 2573
Score = 50.0 bits (114), Expect = 3e-05
Identities = 98/496 (19%), Positives = 194/496 (39%), Gaps = 34/496 (6%)
Query: 150 EKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQA-SRT 208
+K L+L E+ L +E+ G +AK +TLL + + K +++ S+
Sbjct: 1653 QKILELEEENDRLRAEVHPA-----GDTAKECMETLLSSNASMKEELERVKMEYETLSKK 1707
Query: 209 LVN--RDYTNLSKNVL-AKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTEL 265
+ + +LS+ V K +E + TE V E + I E
Sbjct: 1708 FQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQS----IPGET 1763
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI-----EIEQLNARVVEAETKLK 320
D+ ++ E+V + + D S I +I+QL R+ E + K
Sbjct: 1764 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEE-K 1822
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
+ + L+ + L + + LQ+ + K +L +IQ V + +
Sbjct: 1823 QKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1882
Query: 381 DQYGVAQRRIQSLTGEVEEIRGNYEQAL---RVKRS-VEQQYEESQTRVNELTVINVNLS 436
++ + R+ + E+ GNY Q + ++K +E + + + V+EL L
Sbjct: 1883 EEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLV 1942
Query: 437 SSKAKIEQEL------AIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQERIV 489
K K+E E+ I A + K + E + Q E+K + QE+I
Sbjct: 1943 KEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKIS 2002
Query: 490 KIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETI 549
+E K+LE V+ S + E+ + K +A + ++ LD+ + A +
Sbjct: 2003 ALERTVKALEF-VQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVL 2061
Query: 550 --KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTR 607
+ KKE Q + ++ + QK+ L+ LE+ +K K+ + E+ ++
Sbjct: 2062 ADNLKLKKELQSNKESVKSQMKQKDED-LERRLEQAEEKHLKEKKNMQEKLDALRREKVH 2120
Query: 608 VRRFQRELEAAEDRAD 623
+ E++ ++ D
Sbjct: 2121 LEETIGEIQVTLNKKD 2136
Score = 48.8 bits (111), Expect = 6e-05
Identities = 50/220 (22%), Positives = 100/220 (45%), Gaps = 12/220 (5%)
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQE 486
+LT +N + KA+ L ++++K + + E ++ ++KH L E++E
Sbjct: 64 KLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIE-KIKHK---LQEKEE 119
Query: 487 RIVKIEAVKKSLEIEVK-NISVRLEE--VEANAIVGGKRIISKLEARIKDMELELDEEKR 543
I ++A + E S +EE + + + IS L+A++ + E +
Sbjct: 120 LISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAE---QAA 176
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE-KTSQKVSIYKRQLAEQEGMSQ 602
+ + +++R+K+ + E ++ ED+ + Q +E + QK+ + +R+L E E
Sbjct: 177 QLSSMQQVVREKDARF-ETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLV 235
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTT 642
V Q+EL AAE R + L + A+H T T
Sbjct: 236 GRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 275
Score = 48.8 bits (111), Expect = 6e-05
Identities = 93/510 (18%), Positives = 219/510 (42%), Gaps = 35/510 (6%)
Query: 143 KKRMQEIEKELD-LYEKEVNLGSELRQK-AAMYRGKSAKAIAQTLLEESRRNVQNERMYK 200
KK + E+E+E L +++ + SE+R++ +G + ++ +E + ++ ++
Sbjct: 1928 KKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEV 1987
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVT-ESITETVRVRETSPTTCVV 259
Q + L + V A +++++ D +T E++ + V R+ +
Sbjct: 1988 KQLQKDCIRYQEKISALERTVKALEFVQTESQK--DLEITKENLAQAVEHRKKAQA---- 2041
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
+ + +D++ L + +K +L + S+ + E L R+ +AE K
Sbjct: 2042 ELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKD-EDLERRLEQAEEKH 2100
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
E KK +Q ++ L +T ++Q T+ K+ ++ ++Q + D QL
Sbjct: 2101 LKE----KKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAF 2156
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES----QTRVNELTVINVNL 435
Q + E ++ + A++ K + E++ + ++ ++++ L
Sbjct: 2157 TKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2216
Query: 436 SSSKAKIEQELAIVAADYD-EITKELRIADE---RYQRVQTELKHTVEHLHEEQERIVKI 491
+ +++E + I + E+ + ++ D + + ++L+ T H Q + K+
Sbjct: 2217 KINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKL 2276
Query: 492 EAVKKSLEIEVKNISVRLEEV-EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK 550
E+ KSL+ ++ ++S LE+ E + G II + EA I++ + ++ + ++
Sbjct: 2277 ESELKSLKDQLTDLSNSLEKCKEQKGNLEG--IIRQQEADIQNSKFSYEQLE----TDLQ 2330
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ----LAEQEGMSQQSVT 606
R+ +L E I ++QK ISLL E ++ ++Q + E E + Q
Sbjct: 2331 ASRELTSRLHEEINM--KEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEE 2388
Query: 607 RVRRFQRELEAAEDRADVAESNLSLIRAKH 636
+ E + A D+ + L I+ ++
Sbjct: 2389 ENIVLEEENKKAVDKTNQLMETLKTIKKEN 2418
Score = 46.4 bits (105), Expect = 3e-04
Identities = 86/484 (17%), Positives = 213/484 (44%), Gaps = 44/484 (9%)
Query: 144 KRMQEIEKEL-DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+R+++++ EL ++ +K +G E R K + R A I++ + +++Q E
Sbjct: 1418 ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEE------ 1471
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
+R + R L K+L + ++ S ++ +++ + + + + ++
Sbjct: 1472 LSLARGTIER---------LTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD 1522
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
L ++N L+ E++K L++ L + ++ EIE L + + T+ + +
Sbjct: 1523 RSL--LENQ---SLSSSCESLK----LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEK 1573
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
++K+ +I + E +V+N+ +Q ++ + E+ + + T Q
Sbjct: 1574 HKELQKEYEILLQSYE---NVSNEAE-RIQHVVEAVRQEKQELYGKLRSTEANKKETEKQ 1629
Query: 383 YGVAQRRIQSLTGEVEEI-RGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAK 441
A++ ++ + ++ + + ++ L ++ ++ E + L SS A
Sbjct: 1630 LQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNAS 1689
Query: 442 IEQELAIVAADYDEITKELRI----ADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+++EL V +Y+ ++K+ + D + VQ +LKH +E +Q + E
Sbjct: 1690 MKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQ-DLKHQIEGNVSKQANLEATEKHDNQ 1748
Query: 498 LEI-EVKNISVRLEEVEANAI-VGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
+ E S+ E E +++ + + S+ K + ++ H E L++
Sbjct: 1749 TNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQI 1808
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG---MSQQSVTRVRRFQ 612
+ QLKE I EE+++ +LE ++K ++ Q++ ++G M Q+ VT++
Sbjct: 1809 D-QLKERIAGLEEEKQKNKEFSQTLE--NEKNTLLS-QISTKDGELKMLQEEVTKMNLLN 1864
Query: 613 RELE 616
++++
Sbjct: 1865 QQIQ 1868
Score = 44.8 bits (101), Expect = 0.001
Identities = 75/396 (18%), Positives = 177/396 (44%), Gaps = 51/396 (12%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELE-LSLDVANK-TNID-LQKTIKKQSL 360
+++QL + EAE + + + + ++ LS++ +K I+ LQ + L
Sbjct: 731 QVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQL 790
Query: 361 QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-----------LR 409
Q +E T +Q QLQ + R++ ++ +VEE+ Q L
Sbjct: 791 QFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLE 850
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRI---ADE- 465
KR VE + + + ++T I+ +++ ++ +E + + + ++L + A+E
Sbjct: 851 KKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEA 910
Query: 466 RYQRVQ--TELKHTVEHLHEEQERIVKI--EAVKKSLEIEVKNISVRLEEVEANAIVGGK 521
+ ++V+ E+ ++ ++E +I E ++ ++ K R +++A A++ K
Sbjct: 911 KKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQA-ALINRK 969
Query: 522 RIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLE 581
++ ++ +R+++ L +E ++ L + ER + EED++N + +
Sbjct: 970 ELLQRV-SRLEEELANLKDESKKEIP----LSETERG------EVEEDKENKEYSEKCVT 1018
Query: 582 KTSQKVSIYKRQ---------------LAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
Q++ IY +Q L E+ +Q V++ + L+ ++ D+ +
Sbjct: 1019 SKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQ 1078
Query: 627 SNLSLIRAKHRTFVTTST--VPGSQVYLVQESRALS 660
+ +S +A + +T++T G V LV+E+ +S
Sbjct: 1079 AEISENQAIIQKLITSNTDASDGDSVALVKETVVIS 1114
Score = 44.0 bits (99), Expect = 0.002
Identities = 88/469 (18%), Positives = 201/469 (42%), Gaps = 39/469 (8%)
Query: 220 NVLAKALMESKA-MNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNE 278
N + K + +KA + S + + E + V T P + +L D S + E
Sbjct: 52 NKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQS-----EEQLSKHDKSSTEEEME 106
Query: 279 LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELE 338
+++ + + I ++ T + EQ E E + + +K+ I + +
Sbjct: 107 IEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQ 166
Query: 339 LSLDVANKTN--IDLQKTIKKQSLQL-TEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTG 395
LS A + +Q+ ++++ + T+++ H DE+ QL D Q++++ L
Sbjct: 167 LSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELL-QLVTQADVETEMQQKLRVLQR 225
Query: 396 EVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDE 455
++EE + +V ++Q+ ++ R N+ +++ L +A+ V + +E
Sbjct: 226 KLEEHEESLVGRAQVVDLLQQELTAAEQR-NQ--ILSQQLQQMEAEHNTLRNTVETEREE 282
Query: 456 ----ITK-ELRIADER--YQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVR 508
+ K EL +A+ + + +Q E+ H +E + + ++E+ +LE + K
Sbjct: 283 SKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHK---AE 339
Query: 509 LEEVEANAIV---GGKRIISKLEARIKDMELELDEEKRRHA-ETIKILRKKERQLKEVII 564
+EE ++ + G+ + S +A +KD +L ++K A ++ + +++ E QL++
Sbjct: 340 MEEKTSHILSLQKTGQELQSACDA-LKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSK 398
Query: 565 QCEEDQKNISLLQDSLEKTSQKVSIYKR--QLAEQEGMS--QQSVTRVRRFQR------- 613
+ + + L Q + +Y Q +E ++ Q+ V + +
Sbjct: 399 EISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSI 458
Query: 614 ELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSE 662
ELE + + S ++L+ A++RT V + + R+ S+E
Sbjct: 459 ELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAE 507
Score = 39.1 bits (87), Expect = 0.049
Identities = 68/348 (19%), Positives = 153/348 (43%), Gaps = 25/348 (7%)
Query: 286 FDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVAN 345
+++L + ++ KQ S + V++ K S + + +L ++ L+ N
Sbjct: 2815 WNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQIN 2874
Query: 346 KTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL-QVTLD-QYGVAQRRIQSLTGEVEEIRGN 403
+ +L +K Q + + + +Q +L Q L Q+ + Q R++ + E+ E R
Sbjct: 2875 QEITELHP-LKAQLQEYQDKTKAFQIMQEELRQENLSWQHELDQLRMEKSSWEIHERRMK 2933
Query: 404 YEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA 463
EQ L +QQ Q + EL + K + +++ + + + ++ L
Sbjct: 2934 -EQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYE 2992
Query: 464 DERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRL----EEVEANAIVG 519
E ++T+L +++ +H+++ RI ++ + L E +S++L + + N
Sbjct: 2993 TEL---LRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHY 3049
Query: 520 GKRI--ISKLEARIKDME---LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNIS 574
G + + LE ++++++ L +D E + RK + + + E Q++ S
Sbjct: 3050 GDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPE------ELREPQQSFS 3103
Query: 575 LLQDSLEKTSQKVSIYKRQLAEQ--EGMSQQSVTRVRRFQ-RELEAAE 619
Q L T Q+V+ ++ L E+ + ++ ++ V Q R LE +E
Sbjct: 3104 EAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRLEHSE 3151
>AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha striated
muscle isoform protein.
Length = 284
Score = 64.5 bits (150), Expect = 1e-09
Identities = 56/262 (21%), Positives = 123/262 (46%), Gaps = 16/262 (6%)
Query: 299 KQTSIEIEQLNA--RVVEAETKLKSEVTRIKK------KLQIQITELELSLDVANKTNID 350
K +++++ NA R +AE K+ R K+ LQ ++ E LD ++ D
Sbjct: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKD 66
Query: 351 LQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRV 410
Q+ ++ + T+ + + R++Q+ ++ AQ R+ + ++EE +++ R
Sbjct: 67 AQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERG 126
Query: 411 KRSVEQ--QYEESQTRVNELTVINVNLSSSKA-----KIEQELAIVAADYDEITKELRIA 463
+ +E Q +E + + E+ + + A ++ ++L I+ +D + + ++
Sbjct: 127 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 186
Query: 464 DERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI 523
+ + ++ ELK L + + K + E E+K +S +L+E E A +R
Sbjct: 187 EGKCAELEEELKTVTNDLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEF-AERS 245
Query: 524 ISKLEARIKDMELELDEEKRRH 545
++KLE I D+E EL +K ++
Sbjct: 246 VTKLEKSIDDLEDELYAQKLKY 267
Score = 48.4 bits (110), Expect = 8e-05
Identities = 42/205 (20%), Positives = 100/205 (48%), Gaps = 24/205 (11%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+++E A+ A+ E K + A++R ++++ EL + L ++ + K K +
Sbjct: 12 KLDKENALDRAEQAEADK--KAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE 69
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
+++ + + EA+ ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 70 KLELAEKKATDAEAD--------VASLNRRIQLVEEELDRAQERLATALQKLEEAEKA-- 119
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------- 613
+E ++ + +++ +K +K+ I + QL E + +++ + + R
Sbjct: 120 -----ADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIES 174
Query: 614 ELEAAEDRADVAESNLSLIRAKHRT 638
+LE AE+RA+++E + + + +T
Sbjct: 175 DLERAEERAELSEGKCAELEEELKT 199
>AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein.
Length = 742
Score = 64.5 bits (150), Expect = 1e-09
Identities = 75/350 (21%), Positives = 160/350 (45%), Gaps = 21/350 (6%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+S + S+E+ A++ +L+ + ++ Q ++ ++E+ L + N++L
Sbjct: 169 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQ-ELEQMEIELKRLQQENMNLLSDA 227
Query: 356 KKQSLQLTEIQTHYDEVQR--QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
+ + E+ ++ R +L+ + +Y I+ VEE++ + + L K
Sbjct: 228 RSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTM 287
Query: 414 VEQQYEESQTR---VNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
+E Q E ++ R ++EL N+ L + +E E + +E+ +E + ++
Sbjct: 288 LEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQS 347
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI-SVRLEEVEANAIVGGKRIISKLEA 529
E H L + EA +KSL EV + S RL ++E + + +L
Sbjct: 348 MDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-QSLTKTVEELRT 406
Query: 530 RIKDME------LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ +E L++++E +R ++ ++IL + Q K+ + C+ K++ + LEKT
Sbjct: 407 TVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKT 466
Query: 584 SQKV---SIYKRQLAEQEGMS-QQSVTRVRRFQRELEAAEDRA-DVAESN 628
+ + S + ++ EQE Q+V+ +R QR +AE R D+ + N
Sbjct: 467 IETLRENSERQIKILEQENEHLNQTVSSLR--QRSQISAEARVKDIEKEN 514
Score = 63.7 bits (148), Expect = 2e-09
Identities = 90/379 (23%), Positives = 176/379 (46%), Gaps = 39/379 (10%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
R+ ++E E K V ELR G ++K I + E R + + E + Q
Sbjct: 386 RLLKLEMENQSLTKTVE---ELRTTVDSVEGNASK-ILKMEKENQRLSKKVEILENEIVQ 441
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
++L N NLSK+ LM+ KA E ET+R + + N
Sbjct: 442 EKQSLQNCQ--NLSKD-----LMKEKAQ-------LEKTIETLRENSERQIKILEQENEH 487
Query: 265 LPAIDNSYLNQLNELKETVKQFD-DLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
L +S L Q +++ + D + IL++S K+TS ++ ++ + ++K E+
Sbjct: 488 LNQTVSS-LRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFE----KRQIKKEL 542
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQ------THYDEVQRQLQ 377
K+K + + ELE L K N LQK I + +I+ + + R+L+
Sbjct: 543 EHYKEKGE-RAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLK 601
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
TLD + +++SL E ++ E+ L ++R+VE + + ++ +L + N L S
Sbjct: 602 KTLDSFKNLTFQLESLEKENSQLD---EENLELRRNVES-LKCASMKMAQLQLENKELES 657
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
K ++++ L ++ A + + T+ L ++ YQ + E + + L ++I ++E+ +
Sbjct: 658 EKEQLKKGLELLKASFKK-TERLEVS---YQGLDIENQRLQKTLENSNKKIQQLESELQD 713
Query: 498 LEIEVKNISVRLEEVEANA 516
LE+E + + LEE++ ++
Sbjct: 714 LEMENQTLQKNLEELKISS 732
Score = 62.5 bits (145), Expect = 5e-09
Identities = 104/506 (20%), Positives = 226/506 (44%), Gaps = 45/506 (8%)
Query: 143 KKRMQEIEKELD-LYEKEVNLGSELRQKAAMYRGK----SAKAIAQTLLEESRRNVQNER 197
K+ ++++E EL L ++ +NL S+ R A MYR + KA+ LE S + ER
Sbjct: 203 KQELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLE-SEVSRYKER 260
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
++ +F +R L ++ + L+E+K M T + ++ + E
Sbjct: 261 LHDIEFYKARV------EELKED--NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQL 312
Query: 258 VVRINT-ELPA-IDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA 315
+++ E+ +D + +L E T++ S+ D S E+EQ++ +
Sbjct: 313 KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSM----DESLHLGWELEQISRTSELS 368
Query: 316 ETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR- 374
E KS + + ++ +LE+ KT +L+ T+ ++I E QR
Sbjct: 369 EAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL 428
Query: 375 QLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVN 434
+V + + + Q + QSL + ++ ++++++E E S+ ++ L N +
Sbjct: 429 SKKVEILENEIVQEK-QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEH 487
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
L+ + + + Q +I+ E R+ D ++ E K E + E ++ KIE
Sbjct: 488 LNQTVSSLRQR--------SQISAEARVKD-----IEKENKILHESIKETSSKLSKIEFE 534
Query: 495 KKSLEIEV---KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI 551
K+ ++ E+ K R EE+E N + ++ L+ +I ++++ ++ + E +
Sbjct: 535 KRQIKKELEHYKEKGERAEELE-NELHHLEKENELLQKKITNLKITCEKIEALEQENSE- 592
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
L ++ R+LK+ + + KN++ +SLEK + ++ +L + + ++ +
Sbjct: 593 LERENRKLKKTL----DSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL 648
Query: 612 QRELEAAEDRADVAESNLSLIRAKHR 637
Q E + E + + L L++A +
Sbjct: 649 QLENKELESEKEQLKKGLELLKASFK 674
>X65873-1|CAA46703.1| 963|Homo sapiens kinesin heavy chain protein.
Length = 963
Score = 63.7 bits (148), Expect = 2e-09
Identities = 113/594 (19%), Positives = 243/594 (40%), Gaps = 33/594 (5%)
Query: 74 EEDLTRISHDIAEQAKRDLNTFTVGKRSPFSVIATAAAANVTKHVGVESVTVXXXXXXXX 133
E++ +I + + + +LN + G+ P AN+ + +T+
Sbjct: 347 EKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATA 406
Query: 134 XXXXXXXXQKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ-TLLEESRRN 192
+R + E+ LY++ + E+ Q++ + + + Q LL +RR+
Sbjct: 407 IGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRD 466
Query: 193 VQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRET 252
N + QA + + + + A+ + + + E + + +
Sbjct: 467 QDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQK 526
Query: 253 SPTTCVVRINTE-LPAIDNSYLNQLNELKET-VKQFDDLSVYILNDSSKQTS----IEIE 306
S T + + L + N + E+ + +K ++ + + N+ KQ I+ E
Sbjct: 527 SATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEE 586
Query: 307 QLNARVVEAETKLKSEV-TRIKKKLQIQITELELS--LDVANKTNIDLQKTIKKQSLQ-- 361
AR+ +K+KSEV T +K+ Q++ T+ E + ++ K Q I + +
Sbjct: 587 FTVARLY--ISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIK 644
Query: 362 -LTEIQTHYDEVQRQLQVTLDQYG--VAQRRIQSLTGEVEEIRGNYEQ-ALRVKRSVEQQ 417
LTE + ++ +RQL+ ++D + Q R Q E+E+ N Q A VK++VEQQ
Sbjct: 645 SLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQ 704
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHT 477
+ + + +SS + ++E + ++ D + +++ + ER + +LK T
Sbjct: 705 IQSHRETHQK------QISSLRDEVEAKAKLI-TDLQDQNQKMMLEQERLRVEHEKLKAT 757
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI-KDMEL 536
+ + + ++ ++ ++K + + + K + L R+ K E+
Sbjct: 758 DQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEI 817
Query: 537 ELDEEKRRHAETIKI--LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
+ D+ A+ KI L QL +V Q D ++ LEK + + + L
Sbjct: 818 DSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKAL 877
Query: 595 AEQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPG 647
++++ +R R R+Q+E+ DR A + ++ R H + PG
Sbjct: 878 ESALKEAKENASRDRKRYQQEV----DRIKEAVRSKNMARRGHSAQIAKPIRPG 927
>BC126281-1|AAI26282.1| 963|Homo sapiens kinesin family member 5B
protein.
Length = 963
Score = 63.7 bits (148), Expect = 2e-09
Identities = 113/594 (19%), Positives = 243/594 (40%), Gaps = 33/594 (5%)
Query: 74 EEDLTRISHDIAEQAKRDLNTFTVGKRSPFSVIATAAAANVTKHVGVESVTVXXXXXXXX 133
E++ +I + + + +LN + G+ P AN+ + +T+
Sbjct: 347 EKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATA 406
Query: 134 XXXXXXXXQKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ-TLLEESRRN 192
+R + E+ LY++ + E+ Q++ + + + Q LL +RR+
Sbjct: 407 IGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRD 466
Query: 193 VQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRET 252
N + QA + + + + A+ + + + E + + +
Sbjct: 467 QDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQK 526
Query: 253 SPTTCVVRINTE-LPAIDNSYLNQLNELKET-VKQFDDLSVYILNDSSKQTS----IEIE 306
S T + + L + N + E+ + +K ++ + + N+ KQ I+ E
Sbjct: 527 SATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEE 586
Query: 307 QLNARVVEAETKLKSEV-TRIKKKLQIQITELELS--LDVANKTNIDLQKTIKKQSLQ-- 361
AR+ +K+KSEV T +K+ Q++ T+ E + ++ K Q I + +
Sbjct: 587 FTVARLY--ISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIK 644
Query: 362 -LTEIQTHYDEVQRQLQVTLDQYG--VAQRRIQSLTGEVEEIRGNYEQ-ALRVKRSVEQQ 417
LTE + ++ +RQL+ ++D + Q R Q E+E+ N Q A VK++VEQQ
Sbjct: 645 SLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQ 704
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHT 477
+ + + +SS + ++E + ++ D + +++ + ER + +LK T
Sbjct: 705 IQSHRETHQK------QISSLRDEVEAKAKLI-TDLQDQNQKMMLEQERLRVEHEKLKAT 757
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI-KDMEL 536
+ + + ++ ++ ++K + + + K + L R+ K E+
Sbjct: 758 DQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEI 817
Query: 537 ELDEEKRRHAETIKI--LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
+ D+ A+ KI L QL +V Q D ++ LEK + + + L
Sbjct: 818 DSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKAL 877
Query: 595 AEQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPG 647
++++ +R R R+Q+E+ DR A + ++ R H + PG
Sbjct: 878 ESALKEAKENASRDRKRYQQEV----DRIKEAVRSKNMARRGHSAQIAKPIRPG 927
>BC126279-1|AAI26280.1| 963|Homo sapiens kinesin family member 5B
protein.
Length = 963
Score = 63.7 bits (148), Expect = 2e-09
Identities = 113/594 (19%), Positives = 243/594 (40%), Gaps = 33/594 (5%)
Query: 74 EEDLTRISHDIAEQAKRDLNTFTVGKRSPFSVIATAAAANVTKHVGVESVTVXXXXXXXX 133
E++ +I + + + +LN + G+ P AN+ + +T+
Sbjct: 347 EKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATA 406
Query: 134 XXXXXXXXQKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ-TLLEESRRN 192
+R + E+ LY++ + E+ Q++ + + + Q LL +RR+
Sbjct: 407 IGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRD 466
Query: 193 VQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRET 252
N + QA + + + + A+ + + + E + + +
Sbjct: 467 QDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQK 526
Query: 253 SPTTCVVRINTE-LPAIDNSYLNQLNELKET-VKQFDDLSVYILNDSSKQTS----IEIE 306
S T + + L + N + E+ + +K ++ + + N+ KQ I+ E
Sbjct: 527 SATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEE 586
Query: 307 QLNARVVEAETKLKSEV-TRIKKKLQIQITELELS--LDVANKTNIDLQKTIKKQSLQ-- 361
AR+ +K+KSEV T +K+ Q++ T+ E + ++ K Q I + +
Sbjct: 587 FTVARLY--ISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIK 644
Query: 362 -LTEIQTHYDEVQRQLQVTLDQYG--VAQRRIQSLTGEVEEIRGNYEQ-ALRVKRSVEQQ 417
LTE + ++ +RQL+ ++D + Q R Q E+E+ N Q A VK++VEQQ
Sbjct: 645 SLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQ 704
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHT 477
+ + + +SS + ++E + ++ D + +++ + ER + +LK T
Sbjct: 705 IQSHRETHQK------QISSLRDEVEAKAKLI-TDLQDQNQKMMLEQERLRVEHEKLKAT 757
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI-KDMEL 536
+ + + ++ ++ ++K + + + K + L R+ K E+
Sbjct: 758 DQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEI 817
Query: 537 ELDEEKRRHAETIKI--LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
+ D+ A+ KI L QL +V Q D ++ LEK + + + L
Sbjct: 818 DSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKAL 877
Query: 595 AEQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPG 647
++++ +R R R+Q+E+ DR A + ++ R H + PG
Sbjct: 878 ESALKEAKENASRDRKRYQQEV----DRIKEAVRSKNMARRGHSAQIAKPIRPG 927
>AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1116
Score = 63.7 bits (148), Expect = 2e-09
Identities = 111/529 (20%), Positives = 242/529 (45%), Gaps = 62/529 (11%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
K++ ++EL L EK+ + L E++Q + Y AIA+ +++S+ Q E++ K
Sbjct: 206 KQIVHFQQELSLSEKKNLTLSKEVQQIQSNYD----IAIAELHVQKSKNQEQEEKIMKLS 261
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVRETSPTTCVVR 260
+ R TN NV LM +K + + DS S + + +R+ S +
Sbjct: 262 NEIETA--TRSITN---NVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDN 316
Query: 261 I-NTELPAIDNSYL-------------NQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
+ NT+L + N YL N+ N +++ + I+ SSK+ S +IE
Sbjct: 317 LPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKK-SHQIE 375
Query: 307 QLNARV--VEAETK-LKSEVTRIKKK-----------LQIQITELELSLDVANKT-NIDL 351
+L ++ ++AE K K E R+K+K + I +L+ L N T ++ +
Sbjct: 376 ELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQI 435
Query: 352 QKTIK-KQSL-QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALR 409
Q ++ K++L +LT+ T Y ++L+ L+ V + L ++ E L+
Sbjct: 436 QHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDILE---KESIILK 492
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR 469
++R++++ E Q V +NV + K+++E+ + + ++ L++ +E +
Sbjct: 493 LERNLKEFQEHLQDSVKNTKDLNVK----ELKLKEEITQLTNNLQDMKHLLQLKEEEEET 548
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLE 528
+ E + E L R ++A + E + ++ +L + + K + + + E
Sbjct: 549 NRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDE 608
Query: 529 ARIKDMEL-ELDEEKRRHAETIKILRKKERQLKE---------VIIQCEEDQKNISLLQD 578
++ +++ EL+++K + ++ + + ++ +QLKE I Q E K++++ +
Sbjct: 609 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 668
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES 627
+E + ++ EQ+ + + + V R ELE +++ + E+
Sbjct: 669 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLET 717
Score = 61.3 bits (142), Expect = 1e-08
Identities = 77/338 (22%), Positives = 161/338 (47%), Gaps = 33/338 (9%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
E L A ++ E +LK+E K +L QI + L ++ K N+ L K ++ +I
Sbjct: 181 EGLRAFLLTIENELKNEKEE-KAELNKQIVHFQQELSLSEKKNLTLSKEVQ-------QI 232
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQALRVKRSVEQ-QYEE 420
Q++YD +L V + + +I L+ E+E I N Q + +++ + +
Sbjct: 233 QSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLD 292
Query: 421 SQTRVNELTVINVNLSSSKAKIEQ----ELAIVAADY--DEITKELRIADERYQRVQTEL 474
S ++++ + ++N+ S+ ++ + +L ++ DY + KE RI + +
Sbjct: 293 SVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR---ENSF 349
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
++E + EE + IVK + KKS +IE + ++E+++A + G K R+K+
Sbjct: 350 HSSIEAIWEECKEIVKASS-KKSHQIE--ELEQQIEKLQAE-VKGYK----DENNRLKEK 401
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
E + ++ + ET+ K+E Q K V + + +++ + +L + +Q V+ YK ++
Sbjct: 402 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQ--IQHVVEGKRALSELTQGVTCYKAKI 459
Query: 595 AEQEG-MSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
E E + Q V R + E + E + + + +L
Sbjct: 460 KELETILETQKVERSHSAKLEQDILEKESIILKLERNL 497
Score = 58.8 bits (136), Expect = 6e-08
Identities = 87/407 (21%), Positives = 185/407 (45%), Gaps = 34/407 (8%)
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVT---ESITETVRV--RETSPTTCVVRINT 263
L+ DY +SK V + E NS S + E E V+ +++ + +
Sbjct: 324 LLGNDYL-VSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIE 382
Query: 264 ELPAIDNSYLNQLNELKETV-KQFDDLS------VYILNDSSKQTSIEIEQLNARVVEAE 316
+L A Y ++ N LKE K DDL + L + ++ ++ ++ VVE +
Sbjct: 383 KLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK 442
Query: 317 TKLKSEVTRIKKKLQIQITELELSLD---VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
L SE+T+ + +I ELE L+ V + L++ I ++ + +++ + E Q
Sbjct: 443 RAL-SELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQ 501
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
LQ ++ + L E+ ++ N + +K ++ + EE +T E +
Sbjct: 502 EHLQDSVKNTKDLNVKELKLKEEITQLTNNLQD---MKHLLQLKEEEEETNRQETEKLKE 558
Query: 434 NLSSSKAK---IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
LS+S A+ ++ +L DY ++ ++L A ++ ++VQ E+ + + +I +
Sbjct: 559 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 618
Query: 491 IEAVKK--SLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEAR---IKDMELELD 539
+E K S E+++K +++ + + N AI +R L + I+DM + L+
Sbjct: 619 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE 678
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
E+++ E ++L K +++ + + E+ ++ + L+ + S K
Sbjct: 679 EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNK 725
Score = 35.5 bits (78), Expect = 0.61
Identities = 113/558 (20%), Positives = 231/558 (41%), Gaps = 65/558 (11%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q+ ++ DL KE+ L E+ Q + K + Q EE N Q K
Sbjct: 501 QEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQ--DMKHLLQLKEEEEETNRQETEKLKE 558
Query: 202 DFQASRTLVNR----------DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVR- 250
+ AS DY +L K L A + K + + V + +R++
Sbjct: 559 ELSASSARTQNLKADLQRKEEDYADL-KEKLTDAKKQIKQVQK-EVSVMRDEDKLLRIKI 616
Query: 251 ---ETSPTTCVVRINTELPAIDNSYLNQLNELK--ETVKQFD----DLSVY--ILND--- 296
E C ++ + I QLN K E ++Q++ DL+V I+ D
Sbjct: 617 NELEKKKNQCSQELDMKQRTIQQ-LKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRM 675
Query: 297 ---SSKQTSIEIEQ-LNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQ 352
+QT +E +Q L A++ E E +L +E+ + K+K T+ + ++ N D+
Sbjct: 676 TLEEQEQTQVEQDQVLEAKLEEVE-RLATELEKWKEKCNDLETKNNQRSNKEHENNTDVL 734
Query: 353 KTIKKQSLQLTEIQTHYD-EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVK 411
+ +L E + Y+ + ++ L+ + A+ E+++ + E+ + +
Sbjct: 735 GKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQ 794
Query: 412 RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADY---DEITKELRIADERY 467
+E + + ++L A +E +L A+++++ +EI + RI E
Sbjct: 795 NEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISET- 853
Query: 468 QRVQTELKH-TVEHLHEEQERIVKIEAVKKSLEI---EVKNISVRLEEVEANAIVGGKRI 523
+++T++ + + ++ E + S EI ++++ SV L+ E +
Sbjct: 854 SKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTENDQSTR 913
Query: 524 ISKLEARIKDMELELDEEKRRH-----AETIKI---LRKKERQLKEVIIQCEEDQKN--- 572
K E I+ L+ ++ +H T+KI ++K +++E +++C E++KN
Sbjct: 914 FPKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKC-ENKKNATP 972
Query: 573 -------ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR-ADV 624
IS ++S K QKV+I SQ S+ V ++ E + D
Sbjct: 973 RTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEGTLQKFGDF 1032
Query: 625 AESNLSLIRAKHRTFVTT 642
+ + S++++K + + T
Sbjct: 1033 LQHSPSILQSKAKKIIET 1050
>AL161932-2|CAH71618.1| 963|Homo sapiens kinesin family member 5B
protein.
Length = 963
Score = 63.7 bits (148), Expect = 2e-09
Identities = 113/594 (19%), Positives = 243/594 (40%), Gaps = 33/594 (5%)
Query: 74 EEDLTRISHDIAEQAKRDLNTFTVGKRSPFSVIATAAAANVTKHVGVESVTVXXXXXXXX 133
E++ +I + + + +LN + G+ P AN+ + +T+
Sbjct: 347 EKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATA 406
Query: 134 XXXXXXXXQKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQ-TLLEESRRN 192
+R + E+ LY++ + E+ Q++ + + + Q LL +RR+
Sbjct: 407 IGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRD 466
Query: 193 VQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRET 252
N + QA + + + + A+ + + + E + + +
Sbjct: 467 QDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQK 526
Query: 253 SPTTCVVRINTE-LPAIDNSYLNQLNELKET-VKQFDDLSVYILNDSSKQTS----IEIE 306
S T + + L + N + E+ + +K ++ + + N+ KQ I+ E
Sbjct: 527 SATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEE 586
Query: 307 QLNARVVEAETKLKSEV-TRIKKKLQIQITELELS--LDVANKTNIDLQKTIKKQSLQ-- 361
AR+ +K+KSEV T +K+ Q++ T+ E + ++ K Q I + +
Sbjct: 587 FTVARLY--ISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIK 644
Query: 362 -LTEIQTHYDEVQRQLQVTLDQYG--VAQRRIQSLTGEVEEIRGNYEQ-ALRVKRSVEQQ 417
LTE + ++ +RQL+ ++D + Q R Q E+E+ N Q A VK++VEQQ
Sbjct: 645 SLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQ 704
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHT 477
+ + + +SS + ++E + ++ D + +++ + ER + +LK T
Sbjct: 705 IQSHRETHQK------QISSLRDEVEAKAKLI-TDLQDQNQKMMLEQERLRVEHEKLKAT 757
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI-KDMEL 536
+ + + ++ ++ ++K + + + K + L R+ K E+
Sbjct: 758 DQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEI 817
Query: 537 ELDEEKRRHAETIKI--LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
+ D+ A+ KI L QL +V Q D ++ LEK + + + L
Sbjct: 818 DSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKAL 877
Query: 595 AEQEGMSQQSVTRVR-RFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPG 647
++++ +R R R+Q+E+ DR A + ++ R H + PG
Sbjct: 878 ESALKEAKENASRDRKRYQQEV----DRIKEAVRSKNMARRGHSAQIAKPIRPG 927
>AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related
protein protein.
Length = 1820
Score = 63.7 bits (148), Expect = 2e-09
Identities = 111/529 (20%), Positives = 242/529 (45%), Gaps = 62/529 (11%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
K++ ++EL L EK+ + L E++Q + Y AIA+ +++S+ Q E++ K
Sbjct: 910 KQIVHFQQELSLSEKKNLTLSKEVQQIQSNYD----IAIAELHVQKSKNQEQEEKIMKLS 965
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVRETSPTTCVVR 260
+ R TN NV LM +K + + DS S + + +R+ S +
Sbjct: 966 NEIETA--TRSITN---NVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDN 1020
Query: 261 I-NTELPAIDNSYL-------------NQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
+ NT+L + N YL N+ N +++ + I+ SSK+ S +IE
Sbjct: 1021 LPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKK-SHQIE 1079
Query: 307 QLNARV--VEAETK-LKSEVTRIKKK-----------LQIQITELELSLDVANKT-NIDL 351
+L ++ ++AE K K E R+K+K + I +L+ L N T ++ +
Sbjct: 1080 ELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQI 1139
Query: 352 QKTIK-KQSL-QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALR 409
Q ++ K++L +LT+ T Y ++L+ L+ V + L ++ E L+
Sbjct: 1140 QHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDILE---KESIILK 1196
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR 469
++R++++ E Q V +NV + K+++E+ + + ++ L++ +E +
Sbjct: 1197 LERNLKEFQEHLQDSVKNTKDLNVK----ELKLKEEITQLTNNLQDMKHLLQLKEEEEET 1252
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLE 528
+ E + E L R ++A + E + ++ +L + + K + + + E
Sbjct: 1253 NRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDE 1312
Query: 529 ARIKDMEL-ELDEEKRRHAETIKILRKKERQLKE---------VIIQCEEDQKNISLLQD 578
++ +++ EL+++K + ++ + + ++ +QLKE I Q E K++++ +
Sbjct: 1313 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1372
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES 627
+E + ++ EQ+ + + + V R ELE +++ + E+
Sbjct: 1373 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLET 1421
Score = 61.3 bits (142), Expect = 1e-08
Identities = 77/338 (22%), Positives = 161/338 (47%), Gaps = 33/338 (9%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
E L A ++ E +LK+E K +L QI + L ++ K N+ L K ++ +I
Sbjct: 885 EGLRAFLLTIENELKNEKEE-KAELNKQIVHFQQELSLSEKKNLTLSKEVQ-------QI 936
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQALRVKRSVEQ-QYEE 420
Q++YD +L V + + +I L+ E+E I N Q + +++ + +
Sbjct: 937 QSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLD 996
Query: 421 SQTRVNELTVINVNLSSSKAKIEQ----ELAIVAADY--DEITKELRIADERYQRVQTEL 474
S ++++ + ++N+ S+ ++ + +L ++ DY + KE RI + +
Sbjct: 997 SVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR---ENSF 1053
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
++E + EE + IVK + KKS +IE + ++E+++A + G K R+K+
Sbjct: 1054 HSSIEAIWEECKEIVKASS-KKSHQIE--ELEQQIEKLQAE-VKGYK----DENNRLKEK 1105
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
E + ++ + ET+ K+E Q K V + + +++ + +L + +Q V+ YK ++
Sbjct: 1106 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQ--IQHVVEGKRALSELTQGVTCYKAKI 1163
Query: 595 AEQEG-MSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
E E + Q V R + E + E + + + +L
Sbjct: 1164 KELETILETQKVERSHSAKLEQDILEKESIILKLERNL 1201
Score = 58.8 bits (136), Expect = 6e-08
Identities = 87/407 (21%), Positives = 185/407 (45%), Gaps = 34/407 (8%)
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVT---ESITETVRV--RETSPTTCVVRINT 263
L+ DY +SK V + E NS S + E E V+ +++ + +
Sbjct: 1028 LLGNDYL-VSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIE 1086
Query: 264 ELPAIDNSYLNQLNELKETV-KQFDDLS------VYILNDSSKQTSIEIEQLNARVVEAE 316
+L A Y ++ N LKE K DDL + L + ++ ++ ++ VVE +
Sbjct: 1087 KLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK 1146
Query: 317 TKLKSEVTRIKKKLQIQITELELSLD---VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
L SE+T+ + +I ELE L+ V + L++ I ++ + +++ + E Q
Sbjct: 1147 RAL-SELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQ 1205
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
LQ ++ + L E+ ++ N + +K ++ + EE +T E +
Sbjct: 1206 EHLQDSVKNTKDLNVKELKLKEEITQLTNNLQD---MKHLLQLKEEEEETNRQETEKLKE 1262
Query: 434 NLSSSKAK---IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
LS+S A+ ++ +L DY ++ ++L A ++ ++VQ E+ + + +I +
Sbjct: 1263 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1322
Query: 491 IEAVKK--SLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEAR---IKDMELELD 539
+E K S E+++K +++ + + N AI +R L + I+DM + L+
Sbjct: 1323 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE 1382
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
E+++ E ++L K +++ + + E+ ++ + L+ + S K
Sbjct: 1383 EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNK 1429
Score = 37.1 bits (82), Expect = 0.20
Identities = 114/558 (20%), Positives = 232/558 (41%), Gaps = 65/558 (11%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q+ ++ DL KE+ L E+ Q + K + Q EE N Q K
Sbjct: 1205 QEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQ--DMKHLLQLKEEEEETNRQETEKLKE 1262
Query: 202 DFQASRTLVNR----------DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVR- 250
+ AS DY +L K L A + K + + V + +R++
Sbjct: 1263 ELSASSARTQNLKADLQRKEEDYADL-KEKLTDAKKQIKQVQK-EVSVMRDEDKLLRIKI 1320
Query: 251 ---ETSPTTCVVRINTELPAIDNSYLNQLNELK--ETVKQFD----DLSVY--ILND--- 296
E C ++ + I QLN K E ++Q++ DL+V I+ D
Sbjct: 1321 NELEKKKNQCSQELDMKQRTIQQ-LKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRM 1379
Query: 297 ---SSKQTSIEIEQ-LNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQ 352
+QT +E +Q L A++ E E +L +E+ + K+K T+ + ++ N D+
Sbjct: 1380 TLEEQEQTQVEQDQVLEAKLEEVE-RLATELEKWKEKCNDLETKNNQRSNKEHENNTDVL 1438
Query: 353 KTIKKQSLQLTEIQTHYD-EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVK 411
+ +L E + Y+ + ++ L+ + A+ E+++ + E+ + +
Sbjct: 1439 GKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQ 1498
Query: 412 RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADY---DEITKELRIADERY 467
+E + + ++L A +E +L A+++++ +EI + RI E
Sbjct: 1499 NEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISET- 1557
Query: 468 QRVQTELKH-TVEHLHEEQERIVKIEAVKKSLEI---EVKNISVRLEEVEANAIVGGKRI 523
+++T++ + + ++ E + S EI ++++ SV L+ EA+
Sbjct: 1558 SKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEASTENDQSTR 1617
Query: 524 ISKLEARIKDMELELDEEKRRH-----AETIKI---LRKKERQLKEVIIQCEEDQKN--- 572
K E I+ L+ ++ +H T+KI ++K +++E +++C E++KN
Sbjct: 1618 FPKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKC-ENKKNATP 1676
Query: 573 -------ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR-ADV 624
IS ++S K QKV+I SQ S+ V ++ E + D
Sbjct: 1677 RTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEGTLQKFGDF 1736
Query: 625 AESNLSLIRAKHRTFVTT 642
+ + S++++K + + T
Sbjct: 1737 LQHSPSILQSKAKKIIET 1754
>DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein
kinase beta (DMPK-like) protein.
Length = 1711
Score = 63.3 bits (147), Expect = 3e-09
Identities = 57/270 (21%), Positives = 130/270 (48%), Gaps = 13/270 (4%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL E+ R+K K+ LE L+ + L++ + + +L ++ + V+++ +
Sbjct: 489 KLNEEIERLKNKIA-DSNRLERQLE----DTVALRQEREDSTQRLRGLEKQHRVVRQEKE 543
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
Q A R++S + +E++ ++Q ++ Q++ E R+ EL +S
Sbjct: 544 ELHKQLVEASERLKS---QAKELKDAHQQ----RKLALQEFSELNERMAELRAQKQKVSR 596
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
E+E+ + D + +E+R A++ + ++ +L V +E++ E K
Sbjct: 597 QLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQ 656
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE-KRRHAETIKILRKKE 556
+E E++ + V+ A A + ++ ISK+++ ++ L +EE RR A + ++ +
Sbjct: 657 MESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVK 716
Query: 557 RQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
+++ + QK I +L+D LEK+ ++
Sbjct: 717 KEVHDSESHQLALQKEILMLKDKLEKSKRE 746
Score = 47.2 bits (107), Expect = 2e-04
Identities = 88/430 (20%), Positives = 188/430 (43%), Gaps = 52/430 (12%)
Query: 177 SAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCD 236
S K+I Q+ +VQ + + +A + R K L++ L ES
Sbjct: 414 SLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRR--LEQEKLELSRKLQESTQTVQSL 471
Query: 237 SRVTESITETVRVRETSPTTCVVRINTELPAIDNSYL--NQLN-ELKETV--KQFDDLSV 291
+ +++ + R +E + ++N E+ + N N+L +L++TV +Q + S
Sbjct: 472 HGSSRALSNSNRDKE------IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDST 525
Query: 292 YILNDSSKQTSI---EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
L KQ + E E+L+ ++VEA +LKS+ +K D +
Sbjct: 526 QRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELK--------------DAHQQRK 571
Query: 349 IDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL 408
+ LQ+ + + ++ E++ +V RQL+ ++ VA T +V+ +R +A
Sbjct: 572 LALQE-FSELNERMAELRAQKQKVSRQLRDKEEEMEVA-------TQKVDAMRQEMRRAE 623
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADYDEITKELRIADERY 467
++++ +E Q +++ ++ + + + ++E EL A+ +
Sbjct: 624 KLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEI 683
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
++++EL+ V EE +V+ EA S +EVKN+ + + E++ + K I+ L
Sbjct: 684 SKIKSELEKKVLFYEEE---LVRREA---SHVLEVKNVKKEVHDSESHQLALQKEIL-ML 736
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+ +++ + E E TIK ++ER + ++ K ++ + L K+
Sbjct: 737 KDKLEKSKRERHNEMEEAVGTIKDKYERERAM------LFDENKKLTAENEKLCSFVDKL 790
Query: 588 SIYKRQLAEQ 597
+ RQL ++
Sbjct: 791 TAQNRQLEDE 800
Score = 33.9 bits (74), Expect = 1.8
Identities = 32/153 (20%), Positives = 73/153 (47%), Gaps = 7/153 (4%)
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKN-ISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
++ L+EE ER+ A LE ++++ +++R E ++ + G LE + + +
Sbjct: 487 IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRG------LEKQHRVVRQ 540
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
E +E ++ E + L+ + ++LK+ Q + + S L + + + + RQL +
Sbjct: 541 EKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRD 600
Query: 597 QEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+E + + +V ++E+ AE E+ L
Sbjct: 601 KEEEMEVATQKVDAMRQEMRRAEKLRKELEAQL 633
>BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein.
Length = 933
Score = 63.3 bits (147), Expect = 3e-09
Identities = 57/270 (21%), Positives = 130/270 (48%), Gaps = 13/270 (4%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL E+ R+K K+ LE L+ + L++ + + +L ++ + V+++ +
Sbjct: 489 KLNEEIERLKNKIA-DSNRLERQLE----DTVALRQEREDSTQRLRGLEKQHRVVRQEKE 543
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
Q A R++S + +E++ ++Q ++ Q++ E R+ EL +S
Sbjct: 544 ELHKQLVEASERLKS---QAKELKDAHQQ----RKLALQEFSELNERMAELRAQKQKVSR 596
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
E+E+ + D + +E+R A++ + ++ +L V +E++ E K
Sbjct: 597 QLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQ 656
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE-KRRHAETIKILRKKE 556
+E E++ + V+ A A + ++ ISK+++ ++ L +EE RR A + ++ +
Sbjct: 657 MESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVK 716
Query: 557 RQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
+++ + QK I +L+D LEK+ ++
Sbjct: 717 KEVHDSESHQLALQKEILMLKDKLEKSKRE 746
Score = 47.2 bits (107), Expect = 2e-04
Identities = 88/430 (20%), Positives = 188/430 (43%), Gaps = 52/430 (12%)
Query: 177 SAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCD 236
S K+I Q+ +VQ + + +A + R K L++ L ES
Sbjct: 414 SLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRR--LEQEKLELSRKLQESTQTVQSL 471
Query: 237 SRVTESITETVRVRETSPTTCVVRINTELPAIDNSYL--NQLN-ELKETV--KQFDDLSV 291
+ +++ + R +E + ++N E+ + N N+L +L++TV +Q + S
Sbjct: 472 HGSSRALSNSNRDKE------IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDST 525
Query: 292 YILNDSSKQTSI---EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
L KQ + E E+L+ ++VEA +LKS+ +K D +
Sbjct: 526 QRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELK--------------DAHQQRK 571
Query: 349 IDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL 408
+ LQ+ + + ++ E++ +V RQL+ ++ VA T +V+ +R +A
Sbjct: 572 LALQE-FSELNERMAELRAQKQKVSRQLRDKEEEMEVA-------TQKVDAMRQEMRRAE 623
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADYDEITKELRIADERY 467
++++ +E Q +++ ++ + + + ++E EL A+ +
Sbjct: 624 KLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEI 683
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
++++EL+ V EE +V+ EA S +EVKN+ + + E++ + K I+ L
Sbjct: 684 SKIKSELEKKVLFYEEE---LVRREA---SHVLEVKNVKKEVHDSESHQLALQKEIL-ML 736
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+ +++ + E E TIK ++ER + ++ K ++ + L K+
Sbjct: 737 KDKLEKSKRERHNEMEEAVGTIKDKYERERAM------LFDENKKLTAENEKLCSFVDKL 790
Query: 588 SIYKRQLAEQ 597
+ RQL ++
Sbjct: 791 TAQNRQLEDE 800
Score = 33.9 bits (74), Expect = 1.8
Identities = 32/153 (20%), Positives = 73/153 (47%), Gaps = 7/153 (4%)
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKN-ISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
++ L+EE ER+ A LE ++++ +++R E ++ + G LE + + +
Sbjct: 487 IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRG------LEKQHRVVRQ 540
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
E +E ++ E + L+ + ++LK+ Q + + S L + + + + RQL +
Sbjct: 541 EKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRD 600
Query: 597 QEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+E + + +V ++E+ AE E+ L
Sbjct: 601 KEEEMEVATQKVDAMRQEMRRAEKLRKELEAQL 633
>AF223939-1|AAK00630.1| 2073|Homo sapiens ninein isotype 3 protein.
Length = 2073
Score = 63.3 bits (147), Expect = 3e-09
Identities = 67/284 (23%), Positives = 134/284 (47%), Gaps = 30/284 (10%)
Query: 346 KTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR-RIQSLTGEVEEIRGNY 404
K DL K K +SL +E+ H+ ++R+ + L + + RI +L E+ + R
Sbjct: 385 KLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRKEREQI 444
Query: 405 -EQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA-----IVA---ADYDE 455
+QA + + +EQ+ E+++T N + +++E EL ++A D D
Sbjct: 445 LQQAGKQRLELEQEIEKAKTEENYIRDRLALSLKENSRLENELLENAENVLAEKFGDLDP 504
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEE----QERIVKIEAVKKSLEIEVKNISVRLEE 511
+ E + +ER +++ E + L ++ Q + + A + L + +KN EE
Sbjct: 505 SSAEFFLQEERLTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPS--EE 562
Query: 512 VEANAI-VGGKRIISKLEARIKDMELE----LDEEKRRHAETIKILRKK--------ERQ 558
VEAN+ + + + E +M +E +++ K +H I LR + E+Q
Sbjct: 563 VEANSGGIEPEHGLGSEECNPLNMSIEAELVIEQMKEQHHRDICCLRLELEDKVRHYEKQ 622
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQK-VSIYKRQLAEQEGMS 601
L E ++ C++ Q+N+ ++ T +K +S K ++AE +G +
Sbjct: 623 LDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQA 666
Score = 42.3 bits (95), Expect = 0.005
Identities = 91/531 (17%), Positives = 221/531 (41%), Gaps = 39/531 (7%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
+++ +E D ++E+ + E R A+ K A L +E ++ E + +
Sbjct: 1236 EDVSRENDCLQEELRM-METRYDEALENNKELTAEVFRLQDELKKM---EEVTETFLSLE 1291
Query: 207 RTLVNRDYTNLSKNVLAKAL------MESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
++ N NVL L ++ + CD + E+ E + E P +++
Sbjct: 1292 KSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENL---EIEPDGNILQ 1348
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
+N L + ++ + +++ + Y+ ++ ++ ++ + +
Sbjct: 1349 LNQTL----EECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAHEI--AWLHGTIQTH 1402
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
E R++ Q+ + E L +K + Q TI + L+ T++Q +++ ++ + +
Sbjct: 1403 QERPRVQN--QVILEENTTLLGFQDK-HFQHQATIAELELEKTKLQELTRKLKERVTILV 1459
Query: 381 DQ-----YGVAQRRIQSLTGEVEEIRGNYEQALRVKR-SVEQQYEESQTRVNELTVINVN 434
Q +G + ++++ +++ +Q + + R E+ +E+ NE+T +N
Sbjct: 1460 KQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEE 1519
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH--EEQERIVKIE 492
S S K+ L + + T+ ++ + Q++ LK + L +Q + E
Sbjct: 1520 DSISNLKLGT-LYWNSGRMRQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTE 1578
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
+K+ + + K + E + S LE R ++ +E +R ++ ++
Sbjct: 1579 LSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLV 1638
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ-----KVSIYKRQLAEQEGMSQQSVTR 607
E +L EV IQ Q+ LL+D LEK Q +S ++++++ +++ +
Sbjct: 1639 SSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE 1698
Query: 608 VRRFQRELEAAED---RADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
EL + D ++ + E ++ ++ + +++ S SQ+ QE
Sbjct: 1699 KEALSEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQE 1749
Score = 35.1 bits (77), Expect = 0.80
Identities = 57/271 (21%), Positives = 122/271 (45%), Gaps = 18/271 (6%)
Query: 361 QLTEIQTHYDEVQRQLQVT-LDQYGVAQRRIQSLTGEVEEIRG-NYEQALRVKRSVEQQY 418
Q+ E+Q+ +E + Q +V L +++ +G +E G E+ + S+E +
Sbjct: 533 QVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHGLGSEECNPLNMSIEAEL 592
Query: 419 EESQTRVN---ELTVINVNLSSSKAKIEQEL--AIVAADYDEITKELRIADERY--QRVQ 471
Q + ++ + + L E++L +V+ + + R +E + ++
Sbjct: 593 VIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQI 652
Query: 472 TELKHTVEHLHEEQERIVKIEAVKKSL---EIEVKNISVRLEEVEANAIVGGKRIISKLE 528
++LK+ + L + Q ++K EA ++ E E K + V+LEE E + R+ ++E
Sbjct: 653 SDLKNEIAEL-QGQAAVLK-EAHHEATCRHEEEKKQLQVKLEE-EKTHLQEKLRLQHEME 709
Query: 529 ARIKDMELELDEEKRRHA-ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS-QK 586
+ + + + E+ R ++ +K R L + + Q ++Q + + +LEK +K
Sbjct: 710 LKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRK 769
Query: 587 VSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
+ K Q QEG + T R ++EA
Sbjct: 770 ELLEKHQRELQEGREKME-TECNRRTSQIEA 799
Score = 34.7 bits (76), Expect = 1.1
Identities = 66/388 (17%), Positives = 164/388 (42%), Gaps = 24/388 (6%)
Query: 250 RETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
R T V + N + + + Q++ELK +Q D L L+ + Q ++++LN
Sbjct: 1536 RMRQKTETVKQENAAVQKMVENLKKQISELKIKNQQLD-LENTELSQKNSQNQEKLQELN 1594
Query: 310 ARVVEAETKLKSEV--TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQT 367
R+ E + + E + ++++ Q + L+ L+ + L +++ + L +IQT
Sbjct: 1595 QRLTEMLCQKEKEPGNSALEEREQEKFN-LKEELERCKVQSSTLVSSLEAE-LSEVKIQT 1652
Query: 368 HYDEVQRQL-QVTLDQYGVAQR--RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
H + + L + L++ R + ++ + E+ L+ K ++ ++ +
Sbjct: 1653 HIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDK 1712
Query: 425 VNELTVINVNLSSSKAKI---EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
+ + +++ +++ K + E + A + + ++++ ++ Q V ++ L
Sbjct: 1713 LAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDL 1772
Query: 482 HEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGG-----KRII-SKLEARIKDME 535
Q+ ++ SL +++N + E G KR+ KL+ + + +
Sbjct: 1773 RVTQQEKEALKQEVMSLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQ 1832
Query: 536 LELDEEKRR-------HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
L +E R H + R+K RQL+ ++ + N S + E+ +
Sbjct: 1833 QLLWQENERSQTMVQEHQSRLTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQEKLSLK 1892
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELE 616
Q +++ + + V+++ ++ELE
Sbjct: 1893 RECDQFQKEQSPANRKVSQMNSLEQELE 1920
Score = 34.3 bits (75), Expect = 1.4
Identities = 78/395 (19%), Positives = 168/395 (42%), Gaps = 30/395 (7%)
Query: 258 VVRINTELPAIDNSYL-NQLNELKE--TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVE 314
++R +E +NS L N++ L E ++ ++Y + +Q + ++Q NA V +
Sbjct: 1494 LLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLYWNSGRMRQKTETVKQENAAVQK 1553
Query: 315 AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE--- 371
LK +++ +K K Q +L+L ++ N Q+ +++ + +LTE+ ++
Sbjct: 1554 MVENLKKQISELKIKNQ----QLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1609
Query: 372 ---VQRQLQVTLDQYGVAQR-RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE 427
++ + Q + +R ++QS T V + + V+Q+ + + +
Sbjct: 1610 NSALEEREQEKFNLKEELERCKVQSST-LVSSLEAELSEVKIQTHIVQQENHLLKDELEK 1668
Query: 428 LTVIN--VNLSSSKAKIEQELAI---VAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
+ ++ +LS + KI L+ + + + +++EL ++ + + L+H + +
Sbjct: 1669 MKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLAK-SSLLEHRIATMK 1727
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
+EQ+ A KS + + LE+ N + R+ S L ++ E E
Sbjct: 1728 QEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVM 1787
Query: 543 RRHAETIKILRKK-ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
H + K ++ QK +S D L+ + ++QL QE +
Sbjct: 1788 SLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLSW--DKLDHLMNE----EQQLLWQE--N 1839
Query: 602 QQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
++S T V+ Q L + ++ ESNL KH
Sbjct: 1840 ERSQTMVQEHQSRLTHSREKVRQLESNLLPKHQKH 1874
>AF223938-1|AAK00629.1| 2069|Homo sapiens ninein isotype 2 protein.
Length = 2069
Score = 63.3 bits (147), Expect = 3e-09
Identities = 67/284 (23%), Positives = 134/284 (47%), Gaps = 30/284 (10%)
Query: 346 KTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR-RIQSLTGEVEEIRGNY 404
K DL K K +SL +E+ H+ ++R+ + L + + RI +L E+ + R
Sbjct: 385 KLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRKEREQI 444
Query: 405 -EQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA-----IVA---ADYDE 455
+QA + + +EQ+ E+++T N + +++E EL ++A D D
Sbjct: 445 LQQAGKQRLELEQEIEKAKTEENYIRDRLALSLKENSRLENELLENAENVLAEKFGDLDP 504
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEE----QERIVKIEAVKKSLEIEVKNISVRLEE 511
+ E + +ER +++ E + L ++ Q + + A + L + +KN EE
Sbjct: 505 SSAEFFLQEERLTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPS--EE 562
Query: 512 VEANAI-VGGKRIISKLEARIKDMELE----LDEEKRRHAETIKILRKK--------ERQ 558
VEAN+ + + + E +M +E +++ K +H I LR + E+Q
Sbjct: 563 VEANSGGIEPEHGLGSEECNPLNMSIEAELVIEQMKEQHHRDICCLRLELEDKVRHYEKQ 622
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQK-VSIYKRQLAEQEGMS 601
L E ++ C++ Q+N+ ++ T +K +S K ++AE +G +
Sbjct: 623 LDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQA 666
Score = 42.3 bits (95), Expect = 0.005
Identities = 91/531 (17%), Positives = 221/531 (41%), Gaps = 39/531 (7%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
+++ +E D ++E+ + E R A+ K A L +E ++ E + +
Sbjct: 1236 EDVSRENDCLQEELRM-METRYDEALENNKELTAEVFRLQDELKKM---EEVTETFLSLE 1291
Query: 207 RTLVNRDYTNLSKNVLAKAL------MESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
++ N NVL L ++ + CD + E+ E + E P +++
Sbjct: 1292 KSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENL---EIEPDGNILQ 1348
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
+N L + ++ + +++ + Y+ ++ ++ ++ + +
Sbjct: 1349 LNQTL----EECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAHEI--AWLHGTIQTH 1402
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
E R++ Q+ + E L +K + Q TI + L+ T++Q +++ ++ + +
Sbjct: 1403 QERPRVQN--QVILEENTTLLGFQDK-HFQHQATIAELELEKTKLQELTRKLKERVTILV 1459
Query: 381 DQ-----YGVAQRRIQSLTGEVEEIRGNYEQALRVKR-SVEQQYEESQTRVNELTVINVN 434
Q +G + ++++ +++ +Q + + R E+ +E+ NE+T +N
Sbjct: 1460 KQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEE 1519
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH--EEQERIVKIE 492
S S K+ L + + T+ ++ + Q++ LK + L +Q + E
Sbjct: 1520 DSISNLKLGT-LYWNSGRMRQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTE 1578
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
+K+ + + K + E + S LE R ++ +E +R ++ ++
Sbjct: 1579 LSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLV 1638
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ-----KVSIYKRQLAEQEGMSQQSVTR 607
E +L EV IQ Q+ LL+D LEK Q +S ++++++ +++ +
Sbjct: 1639 SSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE 1698
Query: 608 VRRFQRELEAAED---RADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
EL + D ++ + E ++ ++ + +++ S SQ+ QE
Sbjct: 1699 KEALSEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQE 1749
Score = 35.1 bits (77), Expect = 0.80
Identities = 57/271 (21%), Positives = 122/271 (45%), Gaps = 18/271 (6%)
Query: 361 QLTEIQTHYDEVQRQLQVT-LDQYGVAQRRIQSLTGEVEEIRG-NYEQALRVKRSVEQQY 418
Q+ E+Q+ +E + Q +V L +++ +G +E G E+ + S+E +
Sbjct: 533 QVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHGLGSEECNPLNMSIEAEL 592
Query: 419 EESQTRVN---ELTVINVNLSSSKAKIEQEL--AIVAADYDEITKELRIADERY--QRVQ 471
Q + ++ + + L E++L +V+ + + R +E + ++
Sbjct: 593 VIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQI 652
Query: 472 TELKHTVEHLHEEQERIVKIEAVKKSL---EIEVKNISVRLEEVEANAIVGGKRIISKLE 528
++LK+ + L + Q ++K EA ++ E E K + V+LEE E + R+ ++E
Sbjct: 653 SDLKNEIAEL-QGQAAVLK-EAHHEATCRHEEEKKQLQVKLEE-EKTHLQEKLRLQHEME 709
Query: 529 ARIKDMELELDEEKRRHA-ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS-QK 586
+ + + + E+ R ++ +K R L + + Q ++Q + + +LEK +K
Sbjct: 710 LKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRK 769
Query: 587 VSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
+ K Q QEG + T R ++EA
Sbjct: 770 ELLEKHQRELQEGREKME-TECNRRTSQIEA 799
Score = 34.3 bits (75), Expect = 1.4
Identities = 78/395 (19%), Positives = 169/395 (42%), Gaps = 30/395 (7%)
Query: 258 VVRINTELPAIDNSYL-NQLNELKE--TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVE 314
++R +E +NS L N++ L E ++ ++Y + +Q + ++Q NA V +
Sbjct: 1494 LLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLYWNSGRMRQKTETVKQENAAVQK 1553
Query: 315 AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE--- 371
LK +++ +K K Q +L+L ++ N Q+ +++ + +LTE+ ++
Sbjct: 1554 MVENLKKQISELKIKNQ----QLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1609
Query: 372 ---VQRQLQVTLDQYGVAQR-RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE 427
++ + Q + +R ++QS T V + + V+Q+ + + +
Sbjct: 1610 NSALEEREQEKFNLKEELERCKVQSST-LVSSLEAELSEVKIQTHIVQQENHLLKDELEK 1668
Query: 428 LTVIN--VNLSSSKAKIEQELAI---VAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
+ ++ +LS + KI L+ + + + +++EL ++ + + L+H + +
Sbjct: 1669 MKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLAK-SSLLEHRIATMK 1727
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
+EQ+ A KS + + LE+ N + R+ S L ++ E E
Sbjct: 1728 QEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVM 1787
Query: 543 RRHAETIKILRKK-ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
H + K ++ QK +S D L+ + ++QL QE +
Sbjct: 1788 SLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLSW--DKLDHLMNE----EQQLLWQE--N 1839
Query: 602 QQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
++S T V+ + EL + ++ ESNL KH
Sbjct: 1840 ERSQTMVQNTKAELTHSREKVRQLESNLLPKHQKH 1874
Score = 32.3 bits (70), Expect = 5.6
Identities = 65/388 (16%), Positives = 164/388 (42%), Gaps = 24/388 (6%)
Query: 250 RETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
R T V + N + + + Q++ELK +Q D L L+ + Q ++++LN
Sbjct: 1536 RMRQKTETVKQENAAVQKMVENLKKQISELKIKNQQLD-LENTELSQKNSQNQEKLQELN 1594
Query: 310 ARVVEAETKLKSEV--TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQT 367
R+ E + + E + ++++ Q + L+ L+ + L +++ + L +IQT
Sbjct: 1595 QRLTEMLCQKEKEPGNSALEEREQEKFN-LKEELERCKVQSSTLVSSLEAE-LSEVKIQT 1652
Query: 368 HYDEVQRQL-QVTLDQYGVAQR--RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
H + + L + L++ R + ++ + E+ L+ K ++ ++ +
Sbjct: 1653 HIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDK 1712
Query: 425 VNELTVINVNLSSSKAKI---EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
+ + +++ +++ K + E + A + + ++++ ++ Q V ++ L
Sbjct: 1713 LAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDL 1772
Query: 482 HEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGG-----KRII-SKLEARIKDME 535
Q+ ++ SL +++N + E G KR+ KL+ + + +
Sbjct: 1773 RVTQQEKEALKQEVMSLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQ 1832
Query: 536 LELDEEKRRHAETIKIL-------RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
L +E R ++ R+K RQL+ ++ + N S + E+ +
Sbjct: 1833 QLLWQENERSQTMVQNTKAELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQEKLSLK 1892
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELE 616
Q +++ + + V+++ ++ELE
Sbjct: 1893 RECDQFQKEQSPANRKVSQMNSLEQELE 1920
>AF223937-1|AAK00628.1| 2029|Homo sapiens ninein isotype 1 protein.
Length = 2029
Score = 63.3 bits (147), Expect = 3e-09
Identities = 67/284 (23%), Positives = 134/284 (47%), Gaps = 30/284 (10%)
Query: 346 KTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR-RIQSLTGEVEEIRGNY 404
K DL K K +SL +E+ H+ ++R+ + L + + RI +L E+ + R
Sbjct: 385 KLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRKEREQI 444
Query: 405 -EQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA-----IVA---ADYDE 455
+QA + + +EQ+ E+++T N + +++E EL ++A D D
Sbjct: 445 LQQAGKQRLELEQEIEKAKTEENYIRDRLALSLKENSRLENELLENAENVLAEKFGDLDP 504
Query: 456 ITKELRIADERYQRVQTELKHTVEHLHEE----QERIVKIEAVKKSLEIEVKNISVRLEE 511
+ E + +ER +++ E + L ++ Q + + A + L + +KN EE
Sbjct: 505 SSAEFFLQEERLTQMRNEYERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPS--EE 562
Query: 512 VEANAI-VGGKRIISKLEARIKDMELE----LDEEKRRHAETIKILRKK--------ERQ 558
VEAN+ + + + E +M +E +++ K +H I LR + E+Q
Sbjct: 563 VEANSGGIEPEHGLGSEECNPLNMSIEAELVIEQMKEQHHRDICCLRLELEDKVRHYEKQ 622
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQK-VSIYKRQLAEQEGMS 601
L E ++ C++ Q+N+ ++ T +K +S K ++AE +G +
Sbjct: 623 LDETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQA 666
Score = 42.3 bits (95), Expect = 0.005
Identities = 91/531 (17%), Positives = 221/531 (41%), Gaps = 39/531 (7%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
+++ +E D ++E+ + E R A+ K A L +E ++ E + +
Sbjct: 1236 EDVSRENDCLQEELRM-METRYDEALENNKELTAEVFRLQDELKKM---EEVTETFLSLE 1291
Query: 207 RTLVNRDYTNLSKNVLAKAL------MESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
++ N NVL L ++ + CD + E+ E + E P +++
Sbjct: 1292 KSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENL---EIEPDGNILQ 1348
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK 320
+N L + ++ + +++ + Y+ ++ ++ ++ + +
Sbjct: 1349 LNQTL----EECVPRVRSVHHVIEECKQENQYLEGNTQLLEKVKAHEI--AWLHGTIQTH 1402
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTL 380
E R++ Q+ + E L +K + Q TI + L+ T++Q +++ ++ + +
Sbjct: 1403 QERPRVQN--QVILEENTTLLGFQDK-HFQHQATIAELELEKTKLQELTRKLKERVTILV 1459
Query: 381 DQ-----YGVAQRRIQSLTGEVEEIRGNYEQALRVKR-SVEQQYEESQTRVNELTVINVN 434
Q +G + ++++ +++ +Q + + R E+ +E+ NE+T +N
Sbjct: 1460 KQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENSILRNEITTLNEE 1519
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLH--EEQERIVKIE 492
S S K+ L + + T+ ++ + Q++ LK + L +Q + E
Sbjct: 1520 DSISNLKLGT-LYWNSGRMRQKTETVKQENAAVQKMVENLKKQISELKIKNQQLDLENTE 1578
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
+K+ + + K + E + S LE R ++ +E +R ++ ++
Sbjct: 1579 LSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERCKVQSSTLV 1638
Query: 553 RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ-----KVSIYKRQLAEQEGMSQQSVTR 607
E +L EV IQ Q+ LL+D LEK Q +S ++++++ +++ +
Sbjct: 1639 SSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKE 1698
Query: 608 VRRFQRELEAAED---RADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQE 655
EL + D ++ + E ++ ++ + +++ S SQ+ QE
Sbjct: 1699 KEALSEELNSCVDKLAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQE 1749
Score = 35.1 bits (77), Expect = 0.80
Identities = 57/271 (21%), Positives = 122/271 (45%), Gaps = 18/271 (6%)
Query: 361 QLTEIQTHYDEVQRQLQVT-LDQYGVAQRRIQSLTGEVEEIRG-NYEQALRVKRSVEQQY 418
Q+ E+Q+ +E + Q +V L +++ +G +E G E+ + S+E +
Sbjct: 533 QVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHGLGSEECNPLNMSIEAEL 592
Query: 419 EESQTRVN---ELTVINVNLSSSKAKIEQEL--AIVAADYDEITKELRIADERY--QRVQ 471
Q + ++ + + L E++L +V+ + + R +E + ++
Sbjct: 593 VIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHENETHTLEKQI 652
Query: 472 TELKHTVEHLHEEQERIVKIEAVKKSL---EIEVKNISVRLEEVEANAIVGGKRIISKLE 528
++LK+ + L + Q ++K EA ++ E E K + V+LEE E + R+ ++E
Sbjct: 653 SDLKNEIAEL-QGQAAVLK-EAHHEATCRHEEEKKQLQVKLEE-EKTHLQEKLRLQHEME 709
Query: 529 ARIKDMELELDEEKRRHA-ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTS-QK 586
+ + + + E+ R ++ +K R L + + Q ++Q + + +LEK +K
Sbjct: 710 LKARLTQAQASFEREREGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRK 769
Query: 587 VSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
+ K Q QEG + T R ++EA
Sbjct: 770 ELLEKHQRELQEGREKME-TECNRRTSQIEA 799
Score = 34.3 bits (75), Expect = 1.4
Identities = 78/395 (19%), Positives = 169/395 (42%), Gaps = 30/395 (7%)
Query: 258 VVRINTELPAIDNSYL-NQLNELKE--TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVE 314
++R +E +NS L N++ L E ++ ++Y + +Q + ++Q NA V +
Sbjct: 1494 LLRYESEKLQQENSILRNEITTLNEEDSISNLKLGTLYWNSGRMRQKTETVKQENAAVQK 1553
Query: 315 AETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE--- 371
LK +++ +K K Q +L+L ++ N Q+ +++ + +LTE+ ++
Sbjct: 1554 MVENLKKQISELKIKNQ----QLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPG 1609
Query: 372 ---VQRQLQVTLDQYGVAQR-RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE 427
++ + Q + +R ++QS T V + + V+Q+ + + +
Sbjct: 1610 NSALEEREQEKFNLKEELERCKVQSST-LVSSLEAELSEVKIQTHIVQQENHLLKDELEK 1668
Query: 428 LTVIN--VNLSSSKAKIEQELAI---VAADYDEITKELRIADERYQRVQTELKHTVEHLH 482
+ ++ +LS + KI L+ + + + +++EL ++ + + L+H + +
Sbjct: 1669 MKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDKLAK-SSLLEHRIATMK 1727
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
+EQ+ A KS + + LE+ N + R+ S L ++ E E
Sbjct: 1728 QEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDLRVTQQEKEALKQEVM 1787
Query: 543 RRHAETIKILRKK-ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMS 601
H + K ++ QK +S D L+ + ++QL QE +
Sbjct: 1788 SLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLSW--DKLDHLMNE----EQQLLWQE--N 1839
Query: 602 QQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
++S T V+ + EL + ++ ESNL KH
Sbjct: 1840 ERSQTMVQNTKAELTHSREKVRQLESNLLPKHQKH 1874
Score = 32.3 bits (70), Expect = 5.6
Identities = 65/388 (16%), Positives = 164/388 (42%), Gaps = 24/388 (6%)
Query: 250 RETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN 309
R T V + N + + + Q++ELK +Q D L L+ + Q ++++LN
Sbjct: 1536 RMRQKTETVKQENAAVQKMVENLKKQISELKIKNQQLD-LENTELSQKNSQNQEKLQELN 1594
Query: 310 ARVVEAETKLKSEV--TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQT 367
R+ E + + E + ++++ Q + L+ L+ + L +++ + L +IQT
Sbjct: 1595 QRLTEMLCQKEKEPGNSALEEREQEKFN-LKEELERCKVQSSTLVSSLEAE-LSEVKIQT 1652
Query: 368 HYDEVQRQL-QVTLDQYGVAQR--RIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTR 424
H + + L + L++ R + ++ + E+ L+ K ++ ++ +
Sbjct: 1653 HIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLSYNEKLLKEKEALSEELNSCVDK 1712
Query: 425 VNELTVINVNLSSSKAKI---EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHL 481
+ + +++ +++ K + E + A + + ++++ ++ Q V ++ L
Sbjct: 1713 LAKSSLLEHRIATMKQEQKSWEHQSASLKSQLVASQEKVQNLEDTVQNVNLQMSRMKSDL 1772
Query: 482 HEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGG-----KRII-SKLEARIKDME 535
Q+ ++ SL +++N + E G KR+ KL+ + + +
Sbjct: 1773 RVTQQEKEALKQEVMSLHKQLQNAGGKSWAPEIATHPSGLHNQQKRLSWDKLDHLMNEEQ 1832
Query: 536 LELDEEKRRHAETIKIL-------RKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVS 588
L +E R ++ R+K RQL+ ++ + N S + E+ +
Sbjct: 1833 QLLWQENERSQTMVQNTKAELTHSREKVRQLESNLLPKHQKHLNPSGTMNPTEQEKLSLK 1892
Query: 589 IYKRQLAEQEGMSQQSVTRVRRFQRELE 616
Q +++ + + V+++ ++ELE
Sbjct: 1893 RECDQFQKEQSPANRKVSQMNSLEQELE 1920
>AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1711
Score = 63.3 bits (147), Expect = 3e-09
Identities = 57/270 (21%), Positives = 130/270 (48%), Gaps = 13/270 (4%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL E+ R+K K+ LE L+ + L++ + + +L ++ + V+++ +
Sbjct: 489 KLNEEIERLKNKIA-DSNRLERQLE----DTVALRQEREDSTQRLRGLEKQHRVVRQEKE 543
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
Q A R++S + +E++ ++Q ++ Q++ E R+ EL +S
Sbjct: 544 ELHKQLVEASERLKS---QAKELKDAHQQ----RKLALQEFSELNERMAELRAQKQKVSR 596
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
E+E+ + D + +E+R A++ + ++ +L V +E++ E K
Sbjct: 597 QLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQ 656
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE-KRRHAETIKILRKKE 556
+E E++ + V+ A A + ++ ISK+++ ++ L +EE RR A + ++ +
Sbjct: 657 MESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVK 716
Query: 557 RQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
+++ + QK I +L+D LEK+ ++
Sbjct: 717 KEVHDSESHQLALQKEILMLKDKLEKSKRE 746
Score = 47.2 bits (107), Expect = 2e-04
Identities = 88/430 (20%), Positives = 188/430 (43%), Gaps = 52/430 (12%)
Query: 177 SAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCD 236
S K+I Q+ +VQ + + +A + R K L++ L ES
Sbjct: 414 SLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRR--LEQEKLELSRKLQESTQTVQSL 471
Query: 237 SRVTESITETVRVRETSPTTCVVRINTELPAIDNSYL--NQLN-ELKETV--KQFDDLSV 291
+ +++ + R +E + ++N E+ + N N+L +L++TV +Q + S
Sbjct: 472 HGSSRALSNSNRDKE------IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDST 525
Query: 292 YILNDSSKQTSI---EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
L KQ + E E+L+ ++VEA +LKS+ +K D +
Sbjct: 526 QRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELK--------------DAHQQRK 571
Query: 349 IDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL 408
+ LQ+ + + ++ E++ +V RQL+ ++ VA T +V+ +R +A
Sbjct: 572 LALQE-FSELNERMAELRAQKQKVSRQLRDKEEEMEVA-------TQKVDAMRQEMRRAE 623
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADYDEITKELRIADERY 467
++++ +E Q +++ ++ + + + ++E EL A+ +
Sbjct: 624 KLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEI 683
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
++++EL+ V EE +V+ EA S +EVKN+ + + E++ + K I+ L
Sbjct: 684 SKIKSELEKKVLFYEEE---LVRREA---SHVLEVKNVKKEVHDSESHQLALQKEIL-ML 736
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+ +++ + E E TIK ++ER + ++ K ++ + L K+
Sbjct: 737 KDKLEKSKRERHNEMEEAVGTIKDKYERERAM------LFDENKKLTAENEKLCSFVDKL 790
Query: 588 SIYKRQLAEQ 597
+ RQL ++
Sbjct: 791 TAQNRQLEDE 800
Score = 33.9 bits (74), Expect = 1.8
Identities = 32/153 (20%), Positives = 73/153 (47%), Gaps = 7/153 (4%)
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKN-ISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
++ L+EE ER+ A LE ++++ +++R E ++ + G LE + + +
Sbjct: 487 IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRG------LEKQHRVVRQ 540
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
E +E ++ E + L+ + ++LK+ Q + + S L + + + + RQL +
Sbjct: 541 EKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRD 600
Query: 597 QEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+E + + +V ++E+ AE E+ L
Sbjct: 601 KEEEMEVATQKVDAMRQEMRRAEKLRKELEAQL 633
>AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.
Length = 1760
Score = 63.3 bits (147), Expect = 3e-09
Identities = 57/270 (21%), Positives = 130/270 (48%), Gaps = 13/270 (4%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL E+ R+K K+ LE L+ + L++ + + +L ++ + V+++ +
Sbjct: 538 KLNEEIERLKNKIA-DSNRLERQLE----DTVALRQEREDSTQRLRGLEKQHRVVRQEKE 592
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
Q A R++S + +E++ ++Q ++ Q++ E R+ EL +S
Sbjct: 593 ELHKQLVEASERLKS---QAKELKDAHQQ----RKLALQEFSELNERMAELRAQKQKVSR 645
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
E+E+ + D + +E+R A++ + ++ +L V +E++ E K
Sbjct: 646 QLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQ 705
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE-KRRHAETIKILRKKE 556
+E E++ + V+ A A + ++ ISK+++ ++ L +EE RR A + ++ +
Sbjct: 706 MESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVK 765
Query: 557 RQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
+++ + QK I +L+D LEK+ ++
Sbjct: 766 KEVHDSESHQLALQKEILMLKDKLEKSKRE 795
Score = 47.2 bits (107), Expect = 2e-04
Identities = 88/430 (20%), Positives = 188/430 (43%), Gaps = 52/430 (12%)
Query: 177 SAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCD 236
S K+I Q+ +VQ + + +A + R K L++ L ES
Sbjct: 463 SLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRR--LEQEKLELSRKLQESTQTVQSL 520
Query: 237 SRVTESITETVRVRETSPTTCVVRINTELPAIDNSYL--NQLN-ELKETV--KQFDDLSV 291
+ +++ + R +E + ++N E+ + N N+L +L++TV +Q + S
Sbjct: 521 HGSSRALSNSNRDKE------IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDST 574
Query: 292 YILNDSSKQTSI---EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
L KQ + E E+L+ ++VEA +LKS+ +K D +
Sbjct: 575 QRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELK--------------DAHQQRK 620
Query: 349 IDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL 408
+ LQ+ + + ++ E++ +V RQL+ ++ VA T +V+ +R +A
Sbjct: 621 LALQE-FSELNERMAELRAQKQKVSRQLRDKEEEMEVA-------TQKVDAMRQEMRRAE 672
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADYDEITKELRIADERY 467
++++ +E Q +++ ++ + + + ++E EL A+ +
Sbjct: 673 KLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEI 732
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
++++EL+ V EE +V+ EA S +EVKN+ + + E++ + K I+ L
Sbjct: 733 SKIKSELEKKVLFYEEE---LVRREA---SHVLEVKNVKKEVHDSESHQLALQKEIL-ML 785
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+ +++ + E E TIK ++ER + ++ K ++ + L K+
Sbjct: 786 KDKLEKSKRERHNEMEEAVGTIKDKYERERAM------LFDENKKLTAENEKLCSFVDKL 839
Query: 588 SIYKRQLAEQ 597
+ RQL ++
Sbjct: 840 TAQNRQLEDE 849
Score = 33.9 bits (74), Expect = 1.8
Identities = 32/153 (20%), Positives = 73/153 (47%), Gaps = 7/153 (4%)
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKN-ISVRLEEVEANAIVGGKRIISKLEARIKDMEL 536
++ L+EE ER+ A LE ++++ +++R E ++ + G LE + + +
Sbjct: 536 IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRG------LEKQHRVVRQ 589
Query: 537 ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
E +E ++ E + L+ + ++LK+ Q + + S L + + + + RQL +
Sbjct: 590 EKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRD 649
Query: 597 QEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+E + + +V ++E+ AE E+ L
Sbjct: 650 KEEEMEVATQKVDAMRQEMRRAEKLRKELEAQL 682
>BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 62.9 bits (146), Expect = 3e-09
Identities = 99/490 (20%), Positives = 200/490 (40%), Gaps = 27/490 (5%)
Query: 143 KKRMQEIEKELDLYEKEV-NLGSELRQKAAMYRGKSAKAIA-QTLLEESRRNVQNERMYK 200
+++++EI + E EV NL EL ++ YRG + + Q+ LE RR + +
Sbjct: 1171 QEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKE 1230
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
+ + + + + + + + +++ + CD + + E +++T P
Sbjct: 1231 VTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKE 1290
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-----ARVVEA 315
+ E+ Q E +T ++ L + + KQ +E E+ + AR E
Sbjct: 1291 VVQEIL--------QFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEE 1342
Query: 316 ETKLKS-----EVTRIKKK--LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
+++K EV R +++ L+ + + S+DV + L+ +++ + TE++
Sbjct: 1343 LSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQ 1402
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E++R+ Q + QR Q L +E E+ ++ V QQ + Q R + L
Sbjct: 1403 LEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQ-DPQQAREHAL 1461
Query: 429 TVINVNLSSSKAK-IEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQE 486
+ + + + +E EL + + K E++ + VQ E T + + +
Sbjct: 1462 LRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKS 1521
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK-DMELE-LDEEKRR 544
+ + K+ L++EV + RL E+E + K + E K +E E L E RR
Sbjct: 1522 SLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERENLQLETRR 1581
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
I + + R L+ + + + L E K + L E +
Sbjct: 1582 LQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLG 1641
Query: 605 VTRVRRFQRE 614
V+R QRE
Sbjct: 1642 SVAVKREQRE 1651
Score = 56.4 bits (130), Expect = 3e-07
Identities = 86/430 (20%), Positives = 185/430 (43%), Gaps = 16/430 (3%)
Query: 148 EIEKELDLYEKEVNLGSELRQKAAM--YR-GKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
E+EKEL +E+ + L ++ + Y+ K +A+ T + + V E + +
Sbjct: 1243 EMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDP 1302
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
++ V LS+ + +E + + + ++ E RV+E VVR E
Sbjct: 1303 QTKEEVASLRAKLSEEQKKQVDLERERASQ-EEQIARKEEELSRVKERVVQQEVVRYEEE 1361
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE--IEQLNARVVEAETKLKSE 322
P + + ++Q D L + ++T +E +E+L R +A + + E
Sbjct: 1362 -PGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELE-RERQARREAERE 1419
Query: 323 VTRIKKKLQ-IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
V R++++L ++ E E V + + LQ+ +Q+ + ++ +E Q + Q+
Sbjct: 1420 VQRLQQRLAALEQEEAEAREKVTHTQKVVLQQD-PQQAREHALLRLQLEEEQHRRQLLEG 1478
Query: 382 QYGVAQRRIQSLT-GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+ +R++ +L EV+E E K EQ+ + ++ + E + L +
Sbjct: 1479 ELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVS 1538
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
++E L+ + + +KEL E ++Q E E+L E R+ + +
Sbjct: 1539 RLEARLSELEFHNSKSSKELDFLREENHKLQLER----ENLQLETRRLQSEINMAATETR 1594
Query: 501 EVKNISVRLEEVEANAIVGG-KRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+++N++V ++ + +R + L+ KD +LE+DE ++R ++E L
Sbjct: 1595 DLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKREQRENHL 1654
Query: 560 KEVIIQCEED 569
+ I+ D
Sbjct: 1655 RRSIVVIHPD 1664
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/383 (19%), Positives = 169/383 (44%), Gaps = 21/383 (5%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVY--ILNDSSKQTSIEIEQLNARVVEAETKLK 320
TE+ AI+ L L ++Q ++ V L + + +E + ++ ET+ +
Sbjct: 847 TEVYAINRQRLQNLEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETERR 906
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ--LTEIQTHYDEVQRQLQV 378
++ K Q +I L + ++ K + L+ ++Q E Q + Q+
Sbjct: 907 RQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQL 966
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNY--EQALRVKRSVEQQYEESQTRVNELTVINVNLS 436
++ Q ++++L E + Y ++ LR++ Q E Q R EL +
Sbjct: 967 LQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLR-EELEALRRQKG 1025
Query: 437 SSKAKIEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ +A++ VAA +E ++ + ++ ++ ++Q + + E+ + QE + + ++
Sbjct: 1026 AREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEY-QQLQEDHQRQDQLR 1084
Query: 496 KSLEIEVKNISVRLEEVEAN-AIVGGKRIISKLEARIKDM--ELELDEEKRRHAETIKIL 552
+ E E+ + +L+ +E A+ GK + ++ KD E E+ + R++ +
Sbjct: 1085 EKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKA 1144
Query: 553 RKKERQLKEVI--IQCEEDQKNISLLQDSLE-------KTSQKVSIYKRQLAEQEGMSQQ 603
R +R+ E++ I E++ ++Q+ + K +V+ + +L EQE +
Sbjct: 1145 RASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRG 1204
Query: 604 SVTRVRRFQRELEAAEDRADVAE 626
+ ++R +Q ELEA R E
Sbjct: 1205 AEEQLRSYQSELEALRRRGPQVE 1227
Score = 40.7 bits (91), Expect = 0.016
Identities = 67/373 (17%), Positives = 155/373 (41%), Gaps = 37/373 (9%)
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS-EV 323
L ++ NQ N L E + ++ N Q +++ +L A + + L++
Sbjct: 760 LSQMETKLKNQKNLLDEIASREQEVQKICANSQQYQQAVKDYELEAEKLRSLLDLENGRS 819
Query: 324 TRIKKKLQIQITELELSLD-VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ + K+ ++Q ++ + A I +Q LQ E + Q +++VT +
Sbjct: 820 SHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET 879
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ + R S E +IR ++ +R +E + + +Q + L N ++ +
Sbjct: 880 --LQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLR----NQGPQESVV 933
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
+E+ D + +E +Q++Q L EEQ + + L+ E+
Sbjct: 934 RKEVLKKVPD--------PVLEESFQQLQRTLA-------EEQHK-------NQLLQEEL 971
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + ++L +E GG+ + K RI+ + DE + E + R+K + EV
Sbjct: 972 EALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEV 1031
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++ Q+ ++ L + + +KV+ ++++ + + Q ++ Q + + +
Sbjct: 1032 LLL----QQRVAALAEEKSRAQEKVT--EKEVVKLQN-DPQLEAEYQQLQEDHQRQDQLR 1084
Query: 623 DVAESNLSLIRAK 635
+ E LS ++ K
Sbjct: 1085 EKQEEELSFLQDK 1097
>AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21306 fis, clone COL02125. ).
Length = 696
Score = 62.9 bits (146), Expect = 3e-09
Identities = 111/529 (20%), Positives = 242/529 (45%), Gaps = 62/529 (11%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
K++ ++EL L EK+ + L E++Q + Y AIA+ +++S+ Q E++ K
Sbjct: 121 KQIVHSQQELSLSEKKNLTLSKEVQQIQSNYD----IAIAELHVQKSKNQEQEEKIMKLS 176
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVRETSPTTCVVR 260
+ R TN NV LM +K + + DS S + + +R+ S +
Sbjct: 177 NEIETA--TRSITN---NVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDN 231
Query: 261 I-NTELPAIDNSYL-------------NQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
+ NT+L + N YL N+ N +++ + I+ SSK+ S +IE
Sbjct: 232 LPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKK-SHQIE 290
Query: 307 QLNARV--VEAETK-LKSEVTRIK-----------KKLQIQITELELSLDVANKT-NIDL 351
+L ++ ++AE K K E R+K K+ + I +L+ L N T ++ +
Sbjct: 291 ELEQQIEKLQAEVKGYKDENNRLKEREHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQI 350
Query: 352 QKTIK-KQSL-QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALR 409
Q ++ K++L +LT+ T Y ++L+ L+ V + L ++ E L+
Sbjct: 351 QHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDILE---KESIILK 407
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR 469
++R++++ E Q V +NV + K+++E+ + + ++ L++ +E +
Sbjct: 408 LERNLKEFQEHLQDSVKNTKDLNVK----ELKLKEEITQLTNNLQDMKHLLQLKEEEEET 463
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLE 528
+ E + E L R ++A + E + ++ +L + + K + + + E
Sbjct: 464 NRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDE 523
Query: 529 ARIKDMEL-ELDEEKRRHAETIKILRKKERQLKE---------VIIQCEEDQKNISLLQD 578
++ +++ EL+++K + ++ + + ++ +QLKE I Q E K++++ +
Sbjct: 524 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 583
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES 627
+E + ++ EQ+ + + + V R ELE +++ + E+
Sbjct: 584 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLET 632
Score = 60.5 bits (140), Expect = 2e-08
Identities = 77/338 (22%), Positives = 161/338 (47%), Gaps = 33/338 (9%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
E L A ++ E +LK+E K +L QI + L ++ K N+ L K ++ +I
Sbjct: 96 EGLRAFLLTIENELKNEKEE-KAELNKQIVHSQQELSLSEKKNLTLSKEVQ-------QI 147
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQALRVKRSVEQ-QYEE 420
Q++YD +L V + + +I L+ E+E I N Q + +++ + +
Sbjct: 148 QSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLD 207
Query: 421 SQTRVNELTVINVNLSSSKAKIEQ----ELAIVAADY--DEITKELRIADERYQRVQTEL 474
S ++++ + ++N+ S+ ++ + +L ++ DY + KE RI + +
Sbjct: 208 SVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR---ENSF 264
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
++E + EE + IVK + KKS +IE + ++E+++A + G K R+K+
Sbjct: 265 HSSIEAIWEECKEIVKASS-KKSHQIE--ELEQQIEKLQAE-VKGYK----DENNRLKER 316
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
E + ++ + ET+ K+E Q K V + + +++ + +L + +Q V+ YK ++
Sbjct: 317 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQ--IQHVVEGKRALSELTQGVTCYKAKI 374
Query: 595 AEQEG-MSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
E E + Q V R + E + E + + + +L
Sbjct: 375 KELETILETQKVERSHSAKLEQDILEKESIILKLERNL 412
Score = 58.8 bits (136), Expect = 6e-08
Identities = 87/407 (21%), Positives = 185/407 (45%), Gaps = 34/407 (8%)
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVT---ESITETVRV--RETSPTTCVVRINT 263
L+ DY +SK V + E NS S + E E V+ +++ + +
Sbjct: 239 LLGNDYL-VSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIE 297
Query: 264 ELPAIDNSYLNQLNELKETV-KQFDDLS------VYILNDSSKQTSIEIEQLNARVVEAE 316
+L A Y ++ N LKE K DDL + L + ++ ++ ++ VVE +
Sbjct: 298 KLQAEVKGYKDENNRLKEREHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK 357
Query: 317 TKLKSEVTRIKKKLQIQITELELSLD---VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
L SE+T+ + +I ELE L+ V + L++ I ++ + +++ + E Q
Sbjct: 358 RAL-SELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQ 416
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
LQ ++ + L E+ ++ N + +K ++ + EE +T E +
Sbjct: 417 EHLQDSVKNTKDLNVKELKLKEEITQLTNNLQD---MKHLLQLKEEEEETNRQETEKLKE 473
Query: 434 NLSSSKAK---IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
LS+S A+ ++ +L DY ++ ++L A ++ ++VQ E+ + + +I +
Sbjct: 474 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 533
Query: 491 IEAVKK--SLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEAR---IKDMELELD 539
+E K S E+++K +++ + + N AI +R L + I+DM + L+
Sbjct: 534 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE 593
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
E+++ E ++L K +++ + + E+ ++ + L+ + S K
Sbjct: 594 EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNK 640
>AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein.
Length = 1426
Score = 62.9 bits (146), Expect = 3e-09
Identities = 99/490 (20%), Positives = 200/490 (40%), Gaps = 27/490 (5%)
Query: 143 KKRMQEIEKELDLYEKEV-NLGSELRQKAAMYRGKSAKAIA-QTLLEESRRNVQNERMYK 200
+++++EI + E EV NL EL ++ YRG + + Q+ LE RR + +
Sbjct: 841 QEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKE 900
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
+ + + + + + + + +++ + CD + + E +++T P
Sbjct: 901 VTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKE 960
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-----ARVVEA 315
+ E+ Q E +T ++ L + + KQ +E E+ + AR E
Sbjct: 961 VVQEIL--------QFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEE 1012
Query: 316 ETKLKS-----EVTRIKKK--LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
+++K EV R +++ L+ + + S+DV + L+ +++ + TE++
Sbjct: 1013 LSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQ 1072
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E++R+ Q + QR Q L +E E+ ++ V QQ + Q R + L
Sbjct: 1073 LEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQ-DPQQAREHAL 1131
Query: 429 TVINVNLSSSKAK-IEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQE 486
+ + + + +E EL + + K E++ + VQ E T + + +
Sbjct: 1132 LRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKS 1191
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK-DMELE-LDEEKRR 544
+ + K+ L++EV + RL E+E + K + E K +E E L E RR
Sbjct: 1192 SLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERENLQLETRR 1251
Query: 545 HAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQS 604
I + + R L+ + + + L E K + L E +
Sbjct: 1252 LQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLG 1311
Query: 605 VTRVRRFQRE 614
V+R QRE
Sbjct: 1312 SVAVKREQRE 1321
Score = 56.4 bits (130), Expect = 3e-07
Identities = 86/430 (20%), Positives = 185/430 (43%), Gaps = 16/430 (3%)
Query: 148 EIEKELDLYEKEVNLGSELRQKAAM--YR-GKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
E+EKEL +E+ + L ++ + Y+ K +A+ T + + V E + +
Sbjct: 913 EMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDP 972
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
++ V LS+ + +E + + + ++ E RV+E VVR E
Sbjct: 973 QTKEEVASLRAKLSEEQKKQVDLERERASQ-EEQIARKEEELSRVKERVVQQEVVRYEEE 1031
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE--IEQLNARVVEAETKLKSE 322
P + + ++Q D L + ++T +E +E+L R +A + + E
Sbjct: 1032 -PGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELE-RERQARREAERE 1089
Query: 323 VTRIKKKLQ-IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
V R++++L ++ E E V + + LQ+ +Q+ + ++ +E Q + Q+
Sbjct: 1090 VQRLQQRLAALEQEEAEAREKVTHTQKVVLQQD-PQQAREHALLRLQLEEEQHRRQLLEG 1148
Query: 382 QYGVAQRRIQSLT-GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+ +R++ +L EV+E E K EQ+ + ++ + E + L +
Sbjct: 1149 ELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVS 1208
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
++E L+ + + +KEL E ++Q E E+L E R+ + +
Sbjct: 1209 RLEARLSELEFHNSKSSKELDFLREENHKLQLER----ENLQLETRRLQSEINMAATETR 1264
Query: 501 EVKNISVRLEEVEANAIVGG-KRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+++N++V ++ + +R + L+ KD +LE+DE ++R ++E L
Sbjct: 1265 DLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKREQRENHL 1324
Query: 560 KEVIIQCEED 569
+ I+ D
Sbjct: 1325 RRSIVVIHPD 1334
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/383 (19%), Positives = 169/383 (44%), Gaps = 21/383 (5%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVY--ILNDSSKQTSIEIEQLNARVVEAETKLK 320
TE+ AI+ L L ++Q ++ V L + + +E + ++ ET+ +
Sbjct: 517 TEVYAINRQRLQNLEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETERR 576
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ--LTEIQTHYDEVQRQLQV 378
++ K Q +I L + ++ K + L+ ++Q E Q + Q+
Sbjct: 577 RQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQL 636
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNY--EQALRVKRSVEQQYEESQTRVNELTVINVNLS 436
++ Q ++++L E + Y ++ LR++ Q E Q R EL +
Sbjct: 637 LQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLR-EELEALRRQKG 695
Query: 437 SSKAKIEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ +A++ VAA +E ++ + ++ ++ ++Q + + E+ + QE + + ++
Sbjct: 696 AREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEY-QQLQEDHQRQDQLR 754
Query: 496 KSLEIEVKNISVRLEEVEAN-AIVGGKRIISKLEARIKDM--ELELDEEKRRHAETIKIL 552
+ E E+ + +L+ +E A+ GK + ++ KD E E+ + R++ +
Sbjct: 755 EKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKA 814
Query: 553 RKKERQLKEVI--IQCEEDQKNISLLQDSLE-------KTSQKVSIYKRQLAEQEGMSQQ 603
R +R+ E++ I E++ ++Q+ + K +V+ + +L EQE +
Sbjct: 815 RASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRG 874
Query: 604 SVTRVRRFQRELEAAEDRADVAE 626
+ ++R +Q ELEA R E
Sbjct: 875 AEEQLRSYQSELEALRRRGPQVE 897
Score = 40.7 bits (91), Expect = 0.016
Identities = 67/373 (17%), Positives = 155/373 (41%), Gaps = 37/373 (9%)
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS-EV 323
L ++ NQ N L E + ++ N Q +++ +L A + + L++
Sbjct: 430 LSQMETKLKNQKNLLDEIASREQEVQKICANSQQYQQAVKDYELEAEKLRSLLDLENGRS 489
Query: 324 TRIKKKLQIQITELELSLD-VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ + K+ ++Q ++ + A I +Q LQ E + Q +++VT +
Sbjct: 490 SHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET 549
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ + R S E +IR ++ +R +E + + +Q + L N ++ +
Sbjct: 550 --LQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLR----NQGPQESVV 603
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
+E+ D + +E +Q++Q L EEQ + + L+ E+
Sbjct: 604 RKEVLKKVPD--------PVLEESFQQLQRTLA-------EEQHK-------NQLLQEEL 641
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + ++L +E GG+ + K RI+ + DE + E + R+K + EV
Sbjct: 642 EALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEV 701
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++ Q+ ++ L + + +KV+ ++++ + + Q ++ Q + + +
Sbjct: 702 LLL----QQRVAALAEEKSRAQEKVT--EKEVVKLQN-DPQLEAEYQQLQEDHQRQDQLR 754
Query: 623 DVAESNLSLIRAK 635
+ E LS ++ K
Sbjct: 755 EKQEEELSFLQDK 767
>AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 62.5 bits (145), Expect = 5e-09
Identities = 108/523 (20%), Positives = 232/523 (44%), Gaps = 50/523 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+++R Q ++++ +L +V G L++ A+ A+ + +E R +Q +
Sbjct: 1398 ERERAQALQEQGEL---KVAQGKALQENLALLTQTLAEREEE--VETLRGQIQELEKQRE 1452
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC---V 258
+A+ L++ D ++ V + + + + C S V E + V+ RE T +
Sbjct: 1453 MQKAALELLSLDLKKRNQEVDLQQ-EQIQELEKCRS-VLEHLPMAVQEREQKLTVQREQI 1510
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQT------SIEIEQLNARV 312
+ + N +QL EL++ + + + D KQ ++E+E+ N
Sbjct: 1511 RELEKDRETQRNVLEHQLLELEKKDQMIESQRGQV-QDLKKQLVTLECLALELEE-NHHK 1568
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
+E + KL E+ ++ ++ +T L L L+ + + ++ QS Q+ ++++H +
Sbjct: 1569 MECQQKLIKELEGQRETQRVALTHLTLDLE-------ERSQELQAQSSQIHDLESHSTVL 1621
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE---QALRVKRSVEQQYEESQTRVN--- 426
R+LQ + + +I+ L + E + + E Q L +++ Q E+ +TR
Sbjct: 1622 ARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIL 1681
Query: 427 --ELTVINVNLSSSKAKIEQELAIVAADYDE---ITKELRIADERYQRV----QTELKHT 477
+L I ++L ++ + ++ +E +K R + E + + + E++
Sbjct: 1682 EEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQ 1741
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLEARIKDMEL 536
EH+HE QE ++E + L +V S+ L + E +V +++ ++ + +K+ L
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801
Query: 537 --ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
+LDE +R A+ + L +++ ++ Q E ++ LQ +LE+ L
Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHM-------TL 1854
Query: 595 AEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E+ G Q + RR + EL R E L +RA+ R
Sbjct: 1855 KERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESR 1897
Score = 58.4 bits (135), Expect = 8e-08
Identities = 96/523 (18%), Positives = 211/523 (40%), Gaps = 30/523 (5%)
Query: 148 EIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASR 207
+++ E+D KE EL QKA + + + Q R NV E + D +
Sbjct: 453 DLQGEVDSLSKE----RELLQKAREELRQQLEVLEQEAWRLRRVNV--ELQLQGDSAQGQ 506
Query: 208 TLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR--INTEL 265
++ +L+ V + ++ M +++ +ES++E + +RE ++ + + E
Sbjct: 507 KEEQQEELHLA--VRERERLQEMLMG-LEAKQSESLSELITLREALESSHLEGELLRQEQ 563
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
+ + + E + L + + + ++++ LN + + L ++ +
Sbjct: 564 TEVTAALARAEQSIAELSSSENTLKTEVAD--LRAAAVKLSALNEALALDKVGLNQQLLQ 621
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
++++ Q + +E + N +DL + K++ L E TH ++ QLQ +
Sbjct: 622 LEEENQSVCSRMEAAEQARNALQVDLAEAEKRREA-LWEKNTH---LEAQLQKAEEAGAE 677
Query: 386 AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQE 445
Q ++ + E EEI+ ++ + + Q E+ + K + +E
Sbjct: 678 LQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVRE 737
Query: 446 LAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNI 505
A + + ++ + E+ Q + + + L E Q++ IE K LE++++ +
Sbjct: 738 KAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTV 797
Query: 506 SVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET-----IKILRKKERQLK 560
+ E ++ + + +L+ E E D R+ A+ + ++K K
Sbjct: 798 TQAKEVIQGEV----RCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEK 853
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
EV E+ +K S Q L K + + +R+ E E ++ T + Q + E
Sbjct: 854 EVNQLREKWEKERSWHQQELAKALESL---EREKMELEMRLKEQQTEMEAIQAQREEERT 910
Query: 621 RADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSER 663
+A+ A + L K R + T+ +Q L S+ L R
Sbjct: 911 QAESALCQMQLETEKERVSL-LETLLQTQKELADASQQLERLR 952
Score = 52.4 bits (120), Expect = 5e-06
Identities = 98/536 (18%), Positives = 239/536 (44%), Gaps = 56/536 (10%)
Query: 146 MQEIEKELD-LYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+ E EK + L+EK +L ++L++ A G +A + + EE + + +
Sbjct: 647 LAEAEKRREALWEKNTHLEAQLQK--AEEAGAELQADLRDIQEEKEEIQKKLSESRHQQE 704
Query: 205 ASRTLVNRDYTNLSKN--VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
A+ T + + + + VLA+A+ E +A+ V E VR++ V R
Sbjct: 705 AATTQLEQLHQEAKRQEEVLARAVQEKEAL------VREKAALEVRLQ------AVERDR 752
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+L A L+ EL E+ ++ + Q ++I+ V +A+ ++ E
Sbjct: 753 QDL-AEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQT----VTQAKEVIQGE 807
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQ---KTIKKQSLQLTEIQTHYDEVQRQLQVT 379
V +K +L + ++ E D A + + KT +Q E + + + + + +
Sbjct: 808 VRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERS 867
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
Q +A + ++SL E E+ ++ +++ Q EE +T+ E + + L + K
Sbjct: 868 WHQQELA-KALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA-ESALCQMQLETEK 925
Query: 440 AKI---------EQELAIVAADYDEITKELRIADERYQR----VQTELKHTVEHLHE--- 483
++ ++ELA + + + +++++ + Q +QT+L+ L E
Sbjct: 926 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAAR 985
Query: 484 -EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++ + ++ SL + ++ ++E++++ +++++ +++ + +E E+ E+
Sbjct: 986 QHRDDLAALQEESSSLLQDKMDLQKQVEDLKS-------QLVAQDDSQ-RLVEQEVQEKL 1037
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
R E +I ++ ER+ + + E ++ + +LQ++ Q++S ++ + E +G +
Sbjct: 1038 RETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQK 1097
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRA 658
+ ++ ++E++ E AD L+ + +T + S QE++A
Sbjct: 1098 ELSAQMELLRQEVK--EKEADFLAQEAQLLEELEASHITEQQLRAS--LWAQEAKA 1149
Score = 48.8 bits (111), Expect = 6e-05
Identities = 66/332 (19%), Positives = 142/332 (42%), Gaps = 18/332 (5%)
Query: 317 TKLKSE-VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQ 375
T L +E V KL + + + + DV L++ + + +++ T ++QRQ
Sbjct: 1234 TALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQ 1293
Query: 376 LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
L ++ + + SL E+ E+ R E Q E+Q L NL
Sbjct: 1294 LSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENL 1353
Query: 436 SSSKAKIEQ-ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
+ A++E + A+V A + D R R +LK+ E + E+ER +A+
Sbjct: 1354 T---AQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKN--EEVESERER---AQAL 1405
Query: 495 KKSLEIEVKNISVRLEEVE--ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
++ E++V E + + + + L +I+++E + + +K L
Sbjct: 1406 QEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDL 1465
Query: 553 RKKERQL---KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
+K+ +++ +E I + E+ + + L ++++ QK+++ + Q+ E E + T+
Sbjct: 1466 KKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELE---KDRETQRN 1522
Query: 610 RFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
+ +L E + + ES ++ + VT
Sbjct: 1523 VLEHQLLELEKKDQMIESQRGQVQDLKKQLVT 1554
Score = 47.2 bits (107), Expect = 2e-04
Identities = 75/350 (21%), Positives = 147/350 (42%), Gaps = 24/350 (6%)
Query: 331 QIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI 390
Q I EL+ D + L + + + SL L++ + +Q+QLQ +Q + ++ +
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE-LTVINVNLSSSKAKIEQ---EL 446
QS E + +Q L + +QQ + + RV E + L + +++ EL
Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGEL 1861
Query: 447 AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI--EAVKKSLEIEVKN 504
+ +EL + R Q ++ L E+++ ++ + + +++ E EV+
Sbjct: 1862 QDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVET 1921
Query: 505 ISVRLEEVEANAIVGGKRIISKLEA-RIKDMELELDEE-KRRHAETIK--------ILRK 554
+++ ++A A++ K +LEA R + EE R AE ++ L+
Sbjct: 1922 RALQDSWLQAQAVL--KERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQG 1979
Query: 555 KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
KE+ L E + + + LQ SL+ + L QEG Q R + ++
Sbjct: 1980 KEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQ 2039
Query: 615 LEAAEDRADVAESNLSLIRAKHR-TFVTTSTVPGSQVYLVQESRALSSER 663
L+ A +A+ + L + R + S Q ++QE + L ER
Sbjct: 2040 LQQA-----LAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQER 2084
Score = 46.0 bits (104), Expect = 4e-04
Identities = 92/469 (19%), Positives = 187/469 (39%), Gaps = 62/469 (13%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMY-KP 201
++++QE ++ +L E+ + + Q+A R + +A+ Q E+ + Q ER+ K
Sbjct: 1784 QQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ---EQQQAQGQEERVKEKA 1840
Query: 202 DF------QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPT 255
D QA TL R A+ L E A+ + E + +R
Sbjct: 1841 DALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQE 1900
Query: 256 TCVVRIN-----------TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE 304
++ + E A+ +S+L LKE ++ + L + ++ +
Sbjct: 1901 KALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAAR 1960
Query: 305 I--EQLNARVVEAETKLKS------EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK 356
E L + +A L+ E + + L+ L+ SLD + L++ ++
Sbjct: 1961 ARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALR 2020
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGN--YEQALRVKRSV 414
Q ++ + Y E +QLQ L Q R Q +E+ E ++ K+++
Sbjct: 2021 IQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNL 2080
Query: 415 EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL 474
Q+ EE + R +V +EL + A ++ ELR +R
Sbjct: 2081 GQEREEEEIRGLHQSV-------------RELQLTLAQKEQEILELRETQQRNNLEALPH 2127
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
H + E+ +K+++++ L+ E++ + L + EA I + + +D+
Sbjct: 2128 SHKTSPMEEQS---LKLDSLEPRLQRELERLQAALRQTEAREI--------EWREKAQDL 2176
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
L L + K ++ L++ L+ +++ + +Q+ LQD LE T
Sbjct: 2177 ALSLAQTK----ASVSSLQEVAMFLQASVLERDSEQQR---LQDELELT 2218
Score = 44.8 bits (101), Expect = 0.001
Identities = 64/277 (23%), Positives = 129/277 (46%), Gaps = 33/277 (11%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK--KQSLQL-----TEIQTHYD 370
+LKS+ K +LQ ++TEL L + K N D +K IK ++++++ TE+ H
Sbjct: 269 QLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEA 328
Query: 371 EVQRQLQ-VTLDQYGVAQRRIQSLTGEVEEIR--GNYEQALRVKRSVEQQYEESQTRVNE 427
+ R Q L V + Q + E + I +E +L + S+ Q+ + Q
Sbjct: 329 SLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQF-DYQDADKA 387
Query: 428 LTVINVNLSSSKAKIE---QELA-------IVAADYDEITKELRIADERYQRV------- 470
LT++ L+ + ++ Q+LA ++ +D+ +E + +R Q++
Sbjct: 388 LTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTL 447
Query: 471 --QT-ELKHTVEHLHEEQERIVKI-EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISK 526
QT +L+ V+ L +E+E + K E +++ LE+ ++ + RL V + G +
Sbjct: 448 AGQTVDLQGEVDSLSKERELLQKAREELRQQLEV-LEQEAWRLRRVNVELQLQGDSAQGQ 506
Query: 527 LEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
E + +++ L + E +R + + K+ L E+I
Sbjct: 507 KEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELI 543
Score = 42.3 bits (95), Expect = 0.005
Identities = 68/411 (16%), Positives = 166/411 (40%), Gaps = 19/411 (4%)
Query: 222 LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKE 281
L+ L +S+ N ++ +++ ETV + ET+ T + + L+ +K+
Sbjct: 288 LSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKD 347
Query: 282 TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSL 341
+ + I S + S+E++ + + K+ +T ++ L T ++
Sbjct: 348 ITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKA-LTLVRSVL----TRRRQAV 402
Query: 342 DVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
+ Q+ + Q + + ++++LQ + + L GEV+ +
Sbjct: 403 QDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLS 462
Query: 402 GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELR 461
E + + + QQ E + L +NV L +++ + A +E +EL
Sbjct: 463 KERELLQKAREELRQQLEVLEQEAWRLRRVNVEL-----QLQGDSA--QGQKEEQQEELH 515
Query: 462 IADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK 521
+A +R+Q L E ++ + +S +E + + EV A A+ +
Sbjct: 516 LAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTA-ALARAE 574
Query: 522 RIISKLEARIKDMELELDEEKRRHAETIKI---LRKKERQLKEVIIQCEEDQKNISLLQD 578
+ I++L + ++ E+ + + + + L + L + ++Q EE+ +++ +
Sbjct: 575 QSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRME 634
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+ E+ + + LAE E + + + +L+ AE+ +++L
Sbjct: 635 AAEQARNALQV---DLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADL 682
Score = 32.3 bits (70), Expect = 5.6
Identities = 41/230 (17%), Positives = 102/230 (44%), Gaps = 14/230 (6%)
Query: 406 QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
Q L + ++ +E+ R EL + KA+++ + ++A + K+ +E
Sbjct: 245 QLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQ----NE 300
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEA--------VKKSLEIEVKNIS-VRLEEVEANA 516
Y+++ L+ TVE L +++ EA K SL+ +K+I+ V +EE + A
Sbjct: 301 DYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIA 360
Query: 517 IVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLL 576
G +L++ I + + + + +L ++ + ++++ Q Q+ ++LL
Sbjct: 361 QGSGHENSLELDSSIFS-QFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLL 419
Query: 577 QDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
Q ++ ++ +++L + G + Q E+++ ++ +
Sbjct: 420 QQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQ 469
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associated
protein 1 protein.
Length = 2442
Score = 62.5 bits (145), Expect = 5e-09
Identities = 108/523 (20%), Positives = 232/523 (44%), Gaps = 50/523 (9%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+++R Q ++++ +L +V G L++ A+ A+ + +E R +Q +
Sbjct: 1398 ERERAQALQEQGEL---KVAQGKALQENLALLTQTLAEREEE--VETLRGQIQELEKQRE 1452
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC---V 258
+A+ L++ D ++ V + + + + C S V E + V+ RE T +
Sbjct: 1453 MQKAALELLSLDLKKRNQEVDLQQ-EQIQELEKCRS-VLEHLPMAVQEREQKLTVQREQI 1510
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQT------SIEIEQLNARV 312
+ + N +QL EL++ + + + D KQ ++E+E+ N
Sbjct: 1511 RELEKDRETQRNVLEHQLLELEKKDQMIESQRGQV-QDLKKQLVTLECLALELEE-NHHK 1568
Query: 313 VEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
+E + KL E+ ++ ++ +T L L L+ + + ++ QS Q+ ++++H +
Sbjct: 1569 MECQQKLIKELEGQRETQRVALTHLTLDLE-------ERSQELQAQSSQIHDLESHSTVL 1621
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE---QALRVKRSVEQQYEESQTRVN--- 426
R+LQ + + +I+ L + E + + E Q L +++ Q E+ +TR
Sbjct: 1622 ARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIL 1681
Query: 427 --ELTVINVNLSSSKAKIEQELAIVAADYDE---ITKELRIADERYQRV----QTELKHT 477
+L I ++L ++ + ++ +E +K R + E + + + E++
Sbjct: 1682 EEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQ 1741
Query: 478 VEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLEARIKDMEL 536
EH+HE QE ++E + L +V S+ L + E +V +++ ++ + +K+ L
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801
Query: 537 --ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
+LDE +R A+ + L +++ ++ Q E ++ LQ +LE+ L
Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHM-------TL 1854
Query: 595 AEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
E+ G Q + RR + EL R E L +RA+ R
Sbjct: 1855 KERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESR 1897
Score = 58.0 bits (134), Expect = 1e-07
Identities = 70/370 (18%), Positives = 151/370 (40%), Gaps = 17/370 (4%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
+ ++++ LN + + L ++ +++++ Q + +E + N +DL + K++
Sbjct: 595 RAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRR 654
Query: 359 SLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY 418
L E TH ++ QLQ + Q ++ + E EEI+ ++ + + Q
Sbjct: 655 EA-LWEKNTH---LEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQL 710
Query: 419 EESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTV 478
E+ + K + +E A + + ++ + E+ Q + + +
Sbjct: 711 EQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLE 770
Query: 479 EHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELEL 538
L E Q++ IE K LE++++ ++ E ++ + + +L+ E E
Sbjct: 771 SSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEV----RCLKLELDTERSQAEQER 826
Query: 539 DEEKRRHAET-----IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
D R+ A+ + ++K KEV E+ +K S Q L K + + +R+
Sbjct: 827 DAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESL---ERE 883
Query: 594 LAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLV 653
E E ++ T + Q + E +A+ A + L K R + T+ +Q L
Sbjct: 884 KMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSL-LETLLQTQKELA 942
Query: 654 QESRALSSER 663
S+ L R
Sbjct: 943 DASQQLERLR 952
Score = 53.2 bits (122), Expect = 3e-06
Identities = 68/346 (19%), Positives = 151/346 (43%), Gaps = 20/346 (5%)
Query: 328 KKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQ 387
K L+ ++ +L D +DLQ + S + +Q +E+++QL+V L+Q
Sbjct: 431 KALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEV-LEQEAWRL 489
Query: 388 RRIQ--------SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
RR+ S G+ E+ + A+R + +++ + + +E + L +
Sbjct: 490 RRVNVELQLQGDSAQGQKEDQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREAL 549
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE 499
E ++ + E+T L A++ + + + + + VK+ A+ ++L
Sbjct: 550 ESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALA 609
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDE-EKRRHAETIKILRKKERQ 558
++ ++ +L ++E R+ + +AR ++++L E EKRR A L +K
Sbjct: 610 LDKVGLNQQLLQLEEENQSVCSRMEAAEQAR-NALQVDLAEAEKRREA-----LWEKNTH 663
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
L+ + + EE LQ L ++ +++L+E + + T++ + +E +
Sbjct: 664 LEAQLQKAEEAGAE---LQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQ 720
Query: 619 ED-RADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSER 663
E+ A + +L+R K V V + L ++ + LSS +
Sbjct: 721 EEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAK 766
Score = 52.4 bits (120), Expect = 5e-06
Identities = 98/536 (18%), Positives = 239/536 (44%), Gaps = 56/536 (10%)
Query: 146 MQEIEKELD-LYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+ E EK + L+EK +L ++L++ A G +A + + EE + + +
Sbjct: 647 LAEAEKRREALWEKNTHLEAQLQK--AEEAGAELQADLRDIQEEKEEIQKKLSESRHQQE 704
Query: 205 ASRTLVNRDYTNLSKN--VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
A+ T + + + + VLA+A+ E +A+ V E VR++ V R
Sbjct: 705 AATTQLEQLHQEAKRQEEVLARAVQEKEAL------VREKAALEVRLQ------AVERDR 752
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+L A L+ EL E+ ++ + Q ++I+ V +A+ ++ E
Sbjct: 753 QDL-AEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQT----VTQAKEVIQGE 807
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQ---KTIKKQSLQLTEIQTHYDEVQRQLQVT 379
V +K +L + ++ E D A + + KT +Q E + + + + + +
Sbjct: 808 VRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERS 867
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
Q +A + ++SL E E+ ++ +++ Q EE +T+ E + + L + K
Sbjct: 868 WHQQELA-KALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA-ESALCQMQLETEK 925
Query: 440 AKI---------EQELAIVAADYDEITKELRIADERYQR----VQTELKHTVEHLHE--- 483
++ ++ELA + + + +++++ + Q +QT+L+ L E
Sbjct: 926 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAAR 985
Query: 484 -EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++ + ++ SL + ++ ++E++++ +++++ +++ + +E E+ E+
Sbjct: 986 QHRDDLAALQEESSSLLQDKMDLQKQVEDLKS-------QLVAQDDSQ-RLVEQEVQEKL 1037
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
R E +I ++ ER+ + + E ++ + +LQ++ Q++S ++ + E +G +
Sbjct: 1038 RETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQK 1097
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRA 658
+ ++ ++E++ E AD L+ + +T + S QE++A
Sbjct: 1098 ELSAQMELLRQEVK--EKEADFLAQEAQLLEELEASHITEQQLRAS--LWAQEAKA 1149
Score = 48.8 bits (111), Expect = 6e-05
Identities = 66/332 (19%), Positives = 142/332 (42%), Gaps = 18/332 (5%)
Query: 317 TKLKSE-VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQ 375
T L +E V KL + + + + DV L++ + + +++ T ++QRQ
Sbjct: 1234 TALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQ 1293
Query: 376 LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
L ++ + + SL E+ E+ R E Q E+Q L NL
Sbjct: 1294 LSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENL 1353
Query: 436 SSSKAKIEQ-ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
+ A++E + A+V A + D R R +LK+ E + E+ER +A+
Sbjct: 1354 T---AQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKN--EEVESERER---AQAL 1405
Query: 495 KKSLEIEVKNISVRLEEVE--ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
++ E++V E + + + + L +I+++E + + +K L
Sbjct: 1406 QEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDL 1465
Query: 553 RKKERQL---KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
+K+ +++ +E I + E+ + + L ++++ QK+++ + Q+ E E + T+
Sbjct: 1466 KKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELE---KDRETQRN 1522
Query: 610 RFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
+ +L E + + ES ++ + VT
Sbjct: 1523 VLEHQLLELEKKDQMIESQRGQVQDLKKQLVT 1554
Score = 47.2 bits (107), Expect = 2e-04
Identities = 75/350 (21%), Positives = 147/350 (42%), Gaps = 24/350 (6%)
Query: 331 QIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI 390
Q I EL+ D + L + + + SL L++ + +Q+QLQ +Q + ++ +
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE-LTVINVNLSSSKAKIEQ---EL 446
QS E + +Q L + +QQ + + RV E + L + +++ EL
Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGEL 1861
Query: 447 AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI--EAVKKSLEIEVKN 504
+ +EL + R Q ++ L E+++ ++ + + +++ E EV+
Sbjct: 1862 QDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVET 1921
Query: 505 ISVRLEEVEANAIVGGKRIISKLEA-RIKDMELELDEE-KRRHAETIK--------ILRK 554
+++ ++A A++ K +LEA R + EE R AE ++ L+
Sbjct: 1922 RALQDSWLQAQAVL--KERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQG 1979
Query: 555 KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
KE+ L E + + + LQ SL+ + L QEG Q R + ++
Sbjct: 1980 KEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQ 2039
Query: 615 LEAAEDRADVAESNLSLIRAKHR-TFVTTSTVPGSQVYLVQESRALSSER 663
L+ A +A+ + L + R + S Q ++QE + L ER
Sbjct: 2040 LQQA-----LAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQER 2084
Score = 46.0 bits (104), Expect = 4e-04
Identities = 92/469 (19%), Positives = 187/469 (39%), Gaps = 62/469 (13%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMY-KP 201
++++QE ++ +L E+ + + Q+A R + +A+ Q E+ + Q ER+ K
Sbjct: 1784 QQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ---EQQQAQGQEERVKEKA 1840
Query: 202 DF------QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPT 255
D QA TL R A+ L E A+ + E + +R
Sbjct: 1841 DALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQE 1900
Query: 256 TCVVRIN-----------TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE 304
++ + E A+ +S+L LKE ++ + L + ++ +
Sbjct: 1901 KALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAAR 1960
Query: 305 I--EQLNARVVEAETKLKS------EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK 356
E L + +A L+ E + + L+ L+ SLD + L++ ++
Sbjct: 1961 ARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALR 2020
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGN--YEQALRVKRSV 414
Q ++ + Y E +QLQ L Q R Q +E+ E ++ K+++
Sbjct: 2021 IQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNL 2080
Query: 415 EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTEL 474
Q+ EE + R +V +EL + A ++ ELR +R
Sbjct: 2081 GQEREEEEIRGLHQSV-------------RELQLTLAQKEQEILELRETQQRNNLEALPH 2127
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
H + E+ +K+++++ L+ E++ + L + EA I + + +D+
Sbjct: 2128 SHKTSPMEEQS---LKLDSLEPRLQRELERLQAALRQTEAREI--------EWREKAQDL 2176
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
L L + K ++ L++ L+ +++ + +Q+ LQD LE T
Sbjct: 2177 ALSLAQTK----ASVSSLQEVAMFLQASVLERDSEQQR---LQDELELT 2218
Score = 44.4 bits (100), Expect = 0.001
Identities = 64/277 (23%), Positives = 129/277 (46%), Gaps = 33/277 (11%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK--KQSLQL-----TEIQTHYD 370
+LKS+ K +LQ ++TEL L + K N D +K IK ++++++ TE+ H
Sbjct: 269 QLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEA 328
Query: 371 EVQRQLQ-VTLDQYGVAQRRIQSLTGEVEEIR--GNYEQALRVKRSVEQQYEESQTRVNE 427
+ R Q L V + Q + E + I +E +L + S+ Q+ + Q
Sbjct: 329 SLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQF-DYQDADKA 387
Query: 428 LTVINVNLSSSKAKIE---QELA-------IVAADYDEITKELRIADERYQRV------- 470
LT++ L+ + ++ Q+LA ++ +D+ +E + +R Q++
Sbjct: 388 LTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTL 447
Query: 471 --QT-ELKHTVEHLHEEQERIVKI-EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISK 526
QT +L+ V+ L +E+E + K E +++ LE+ ++ + RL V + G +
Sbjct: 448 AGQTVDLQGEVDSLSKERELLQKAREELRQQLEV-LEQEAWRLRRVNVELQLQGDSAQGQ 506
Query: 527 LEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
E + +++ L + E +R + + K+ L E+I
Sbjct: 507 KEDQQEELHLAVRERERLQEMLMGLEAKQSESLSELI 543
Score = 41.1 bits (92), Expect = 0.012
Identities = 67/411 (16%), Positives = 166/411 (40%), Gaps = 19/411 (4%)
Query: 222 LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKE 281
L+ L +S+ N ++ +++ ETV + ET+ T + + L+ +K+
Sbjct: 288 LSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKD 347
Query: 282 TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSL 341
+ + I S + S+E++ + + K+ +T ++ L T ++
Sbjct: 348 ITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKA-LTLVRSVL----TRRRQAV 402
Query: 342 DVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
+ Q+ + Q + + ++++LQ + + L GEV+ +
Sbjct: 403 QDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLS 462
Query: 402 GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELR 461
E + + + QQ E + L +NV L +++ + A ++ +EL
Sbjct: 463 KERELLQKAREELRQQLEVLEQEAWRLRRVNVEL-----QLQGDSA--QGQKEDQQEELH 515
Query: 462 IADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK 521
+A +R+Q L E ++ + +S +E + + EV A A+ +
Sbjct: 516 LAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTA-ALARAE 574
Query: 522 RIISKLEARIKDMELELDEEKRRHAETIKI---LRKKERQLKEVIIQCEEDQKNISLLQD 578
+ I++L + ++ E+ + + + + L + L + ++Q EE+ +++ +
Sbjct: 575 QSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRME 634
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+ E+ + + LAE E + + + +L+ AE+ +++L
Sbjct: 635 AAEQARNALQV---DLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADL 682
Score = 32.7 bits (71), Expect = 4.3
Identities = 49/252 (19%), Positives = 110/252 (43%), Gaps = 24/252 (9%)
Query: 394 TGEVE-EIRGNYEQALRVKRSVEQQYEESQTRVNELTVI-------NVNLSSSKAKIEQE 445
T E+E E ++ +++K + + E Q RV EL+ + N + + +
Sbjct: 253 TQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRET 312
Query: 446 LAIVAADYDEITKE----LRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIE 501
+ I+ ++ E+ + R A E +Q +K + + EE + I + + SLE++
Sbjct: 313 VEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELD 372
Query: 502 VKNISVRLEEVEAN-AIVGGKRIISKLEARIKDMELEL----------DEEKRRHAETIK 550
+I + + +A+ A+ + ++++ ++D+ +L ++ + E K
Sbjct: 373 -SSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGK 431
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRR 610
LR++ ++L ++ DSL K + + + +L +Q + +Q R+RR
Sbjct: 432 ALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRR 491
Query: 611 FQRELEAAEDRA 622
EL+ D A
Sbjct: 492 VNVELQLQGDSA 503
>AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 62.5 bits (145), Expect = 5e-09
Identities = 99/491 (20%), Positives = 201/491 (40%), Gaps = 29/491 (5%)
Query: 143 KKRMQEIEKELDLYEKEV-NLGSELRQKAAMYRGKSAKAIA-QTLLEESRRNVQNERMYK 200
+++++EI + E EV NL EL ++ YRG + + Q+ LE RR + +
Sbjct: 1171 QEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKE 1230
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
+ + + + + + + + +++ + CD + + E +++T P
Sbjct: 1231 VTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKE 1290
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-----ARVVEA 315
+ E+ Q E +T ++ L + + KQ +E E+ + AR E
Sbjct: 1291 VVQEIL--------QFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEE 1342
Query: 316 ETKLKS-----EVTRIKKK--LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
+++K EV R +++ L+ + + S+DV + L+ +++ + TE++
Sbjct: 1343 LSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQ 1402
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E++R+ Q + QR Q L +E E+ ++ V QQ + Q R + L
Sbjct: 1403 LEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQ-DPQQAREHAL 1461
Query: 429 TVINVNLSSSKAK-IEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQE 486
+ + + + +E EL + + K E++ + VQ E T + + +
Sbjct: 1462 LRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKS 1521
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE---LDEEKR 543
+ + K+ L++EV + RL E+E + K + E K ++LE L E R
Sbjct: 1522 SLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHK-LQLERQNLQLETR 1580
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
R I + + R L+ + + + L E K + L E +
Sbjct: 1581 RLQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRL 1640
Query: 604 SVTRVRRFQRE 614
V+R QRE
Sbjct: 1641 GSVAVKREQRE 1651
Score = 55.2 bits (127), Expect = 7e-07
Identities = 85/430 (19%), Positives = 185/430 (43%), Gaps = 16/430 (3%)
Query: 148 EIEKELDLYEKEVNLGSELRQKAAM--YR-GKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
E+EKEL +E+ + L ++ + Y+ K +A+ T + + V E + +
Sbjct: 1243 EMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDP 1302
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
++ V LS+ + +E + + + ++ E RV+E VVR E
Sbjct: 1303 QTKEEVASLRAKLSEEQKKQVDLERERASQ-EEQIARKEEELSRVKERVVQQEVVRYEEE 1361
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE--IEQLNARVVEAETKLKSE 322
P + + ++Q D L + ++T +E +E+L R +A + + E
Sbjct: 1362 -PGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELE-RERQARREAERE 1419
Query: 323 VTRIKKKLQ-IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
V R++++L ++ E E V + + LQ+ +Q+ + ++ +E Q + Q+
Sbjct: 1420 VQRLQQRLAALEQEEAEAREKVTHTQKVVLQQD-PQQAREHALLRLQLEEEQHRRQLLEG 1478
Query: 382 QYGVAQRRIQSLT-GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+ +R++ +L EV+E E K EQ+ + ++ + E + L +
Sbjct: 1479 ELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVS 1538
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
++E L+ + + +KEL E ++Q E ++L E R+ + +
Sbjct: 1539 RLEARLSELEFHNSKSSKELDFLREENHKLQLER----QNLQLETRRLQSEINMAATETR 1594
Query: 501 EVKNISVRLEEVEANAIVGG-KRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+++N++V ++ + +R + L+ KD +LE+DE ++R ++E L
Sbjct: 1595 DLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKREQRENHL 1654
Query: 560 KEVIIQCEED 569
+ I+ D
Sbjct: 1655 RRSIVVIHPD 1664
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/383 (19%), Positives = 169/383 (44%), Gaps = 21/383 (5%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVY--ILNDSSKQTSIEIEQLNARVVEAETKLK 320
TE+ AI+ L L ++Q ++ V L + + +E + ++ ET+ +
Sbjct: 847 TEVYAINRQRLQNLEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETERR 906
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ--LTEIQTHYDEVQRQLQV 378
++ K Q +I L + ++ K + L+ ++Q E Q + Q+
Sbjct: 907 RQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQL 966
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNY--EQALRVKRSVEQQYEESQTRVNELTVINVNLS 436
++ Q ++++L E + Y ++ LR++ Q E Q R EL +
Sbjct: 967 LQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLR-EELEALRRQKG 1025
Query: 437 SSKAKIEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ +A++ VAA +E ++ + ++ ++ ++Q + + E+ + QE + + ++
Sbjct: 1026 AREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEY-QQLQEDHQRQDQLR 1084
Query: 496 KSLEIEVKNISVRLEEVEAN-AIVGGKRIISKLEARIKDM--ELELDEEKRRHAETIKIL 552
+ E E+ + +L+ +E A+ GK + ++ KD E E+ + R++ +
Sbjct: 1085 EKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKA 1144
Query: 553 RKKERQLKEVI--IQCEEDQKNISLLQDSLE-------KTSQKVSIYKRQLAEQEGMSQQ 603
R +R+ E++ I E++ ++Q+ + K +V+ + +L EQE +
Sbjct: 1145 RASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRG 1204
Query: 604 SVTRVRRFQRELEAAEDRADVAE 626
+ ++R +Q ELEA R E
Sbjct: 1205 AEEQLRSYQSELEALRRRGPQVE 1227
Score = 40.7 bits (91), Expect = 0.016
Identities = 67/373 (17%), Positives = 155/373 (41%), Gaps = 37/373 (9%)
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS-EV 323
L ++ NQ N L E + ++ N Q +++ +L A + + L++
Sbjct: 760 LSQMETKLKNQKNLLDEIASREQEVQKICANSQQYQQAVKDYELEAEKLRSLLDLENGRS 819
Query: 324 TRIKKKLQIQITELELSLD-VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ + K+ ++Q ++ + A I +Q LQ E + Q +++VT +
Sbjct: 820 SHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET 879
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ + R S E +IR ++ +R +E + + +Q + L N ++ +
Sbjct: 880 --LQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLR----NQGPQESVV 933
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
+E+ D + +E +Q++Q L EEQ + + L+ E+
Sbjct: 934 RKEVLKKVPD--------PVLEESFQQLQRTLA-------EEQHK-------NQLLQEEL 971
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + ++L +E GG+ + K RI+ + DE + E + R+K + EV
Sbjct: 972 EALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEV 1031
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++ Q+ ++ L + + +KV+ ++++ + + Q ++ Q + + +
Sbjct: 1032 LLL----QQRVAALAEEKSRAQEKVT--EKEVVKLQN-DPQLEAEYQQLQEDHQRQDQLR 1084
Query: 623 DVAESNLSLIRAK 635
+ E LS ++ K
Sbjct: 1085 EKQEEELSFLQDK 1097
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
protein protein.
Length = 2442
Score = 62.5 bits (145), Expect = 5e-09
Identities = 112/525 (21%), Positives = 233/525 (44%), Gaps = 54/525 (10%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+++R Q ++++ +L +V G L++ A+ A+ + +E R +Q +
Sbjct: 1398 ERERAQALQEQGEL---KVAQGKALQENLALLTQTLAEREEE--VETLRGQIQELEKQRE 1452
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
+A+ L++ D ++ V + + + + C S V E + V+ RE T V R
Sbjct: 1453 MQKAALELLSLDLKKRNQEVDLQQ-EQIQELEKCRS-VLEHLPMAVQEREQKLT--VQRE 1508
Query: 262 NTELPAID-----NSYLNQLNELKETVKQFDDLSVYILNDSSKQT------SIEIEQLNA 310
P D N +QL EL++ + + + D KQ ++E+E+ N
Sbjct: 1509 QIREPEKDRETQRNVLEHQLLELEKKDQMIESQRGQV-QDLKKQLVTLECLALELEE-NH 1566
Query: 311 RVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYD 370
+E + KL E+ ++ ++ +T L L L+ + + ++ QS Q+ ++++H
Sbjct: 1567 HKMECQQKLIKELEGQRETQRVALTHLTLDLE-------ERSQELQAQSSQIHDLESHST 1619
Query: 371 EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYE---QALRVKRSVEQQYEESQTRVN- 426
+ R+LQ + + +I+ L + E + + E Q L +++ Q E+ +TR
Sbjct: 1620 VLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTK 1679
Query: 427 ----ELTVINVNLSSSKAKIEQELAIVAADYDE---ITKELRIADERYQRV----QTELK 475
+L I ++L ++ + ++ +E +K R + E + + + E++
Sbjct: 1680 ILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVE 1739
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLEARIKDM 534
EH+HE QE ++E + L +V S+ L + E +V +++ ++ + +K+
Sbjct: 1740 CQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQ 1799
Query: 535 EL--ELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKR 592
L +LDE +R A+ + L +++ ++ Q E ++ LQ +LE+
Sbjct: 1800 SLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHM------- 1852
Query: 593 QLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
L E+ G Q + RR + EL R E L +RA+ R
Sbjct: 1853 TLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESR 1897
Score = 54.8 bits (126), Expect = 9e-07
Identities = 98/536 (18%), Positives = 240/536 (44%), Gaps = 56/536 (10%)
Query: 146 MQEIEKELD-LYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
+ E EK + L+EK +L ++L++ A G +A + + EE + + +
Sbjct: 647 LAEAEKRREALWEKNTHLEAQLQK--AEEAGAELQADLRDIQEEKEEIQKKLSESRHQQE 704
Query: 205 ASRTLVNRDYTNLSKN--VLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
A+ T + + + + VLA+A+ E +A+ V E VR++ V R
Sbjct: 705 AATTQLEQLHQEAKRQEEVLARAVQEKEAL------VREKAALEVRLQ------AVERDR 752
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
+L A L+ EL E+ ++++ Q ++I+ V +A+ ++ E
Sbjct: 753 QDLAA-QLQGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQT----VTQAKEVIQGE 807
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQ---KTIKKQSLQLTEIQTHYDEVQRQLQVT 379
V +K +L + ++ E D A + + KT +Q E + + + + + +
Sbjct: 808 VRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERS 867
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
Q +A + ++SL E E+ ++ +++ Q EE +T+ E + + L + K
Sbjct: 868 WHQQELA-KALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA-ESALCQMQLETEK 925
Query: 440 AKI---------EQELAIVAADYDEITKELRIADERYQR----VQTELKHTVEHLHE--- 483
++ ++ELA + + + +++++ + Q +QT+L+ L E
Sbjct: 926 ERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAAR 985
Query: 484 -EQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
++ + ++ SL + ++ ++E++++ +++++ +++ + +E E+ E+
Sbjct: 986 QHRDDLAALQEESSSLLQDKMDLQKQVEDLKS-------QLVAQDDSQ-RLVEQEVQEKL 1037
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
R E +I ++ ER+ + + E ++ + +LQ++ Q++S ++ + E +G +
Sbjct: 1038 RETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQK 1097
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRA 658
+ ++ ++E++ E AD L+ + +T + S QE++A
Sbjct: 1098 ELSAQMELLRQEVK--EKEADFLAQEAQLLEELEASHITEQQLRAS--LWAQEAKA 1149
Score = 52.4 bits (120), Expect = 5e-06
Identities = 93/524 (17%), Positives = 214/524 (40%), Gaps = 32/524 (6%)
Query: 148 EIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASR 207
+++ E+D KE EL QKA + + + Q R NV E + D +
Sbjct: 453 DLQGEVDSLSKE----RELLQKAREELRQQLEVLEQEAWRLRRVNV--ELQLQGDSAQGQ 506
Query: 208 TLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPA 267
++ +L+ V + ++ M +++ +ES++E + +RE + + + EL
Sbjct: 507 KEEQQEELHLA--VRERERLQEMLMG-LEAKQSESLSELITLREALES---IHLEGELLR 560
Query: 268 IDNSYLNQ-LNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVT 324
+ + + L ++++ + + + + + ++++ LN + + L ++
Sbjct: 561 QEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLL 620
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
+++++ Q + +E + N +DL + K++ L E TH ++ QLQ +
Sbjct: 621 QLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREA-LWEKNTH---LEAQLQKAEEAGA 676
Query: 385 VAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQ 444
Q ++ + E EEI+ ++ + + Q E+ + K + +
Sbjct: 677 ELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVR 736
Query: 445 ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKN 504
E A + + ++ + + Q + + + L E Q++ I+ + LE++++
Sbjct: 737 EKAALEVRLQAVERDRQDLAAQLQGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQT 796
Query: 505 ISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET-----IKILRKKERQL 559
++ E ++ + + +L+ E E D R+ A+ + ++K
Sbjct: 797 VTQAKEVIQGEV----RCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHE 852
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
KEV E+ +K S Q L K + + +R+ E E ++ T + Q + E
Sbjct: 853 KEVNQLREKWEKERSWHQQELAKALESL---EREKMELEMRLKEQQTEMEAIQAQREEER 909
Query: 620 DRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSER 663
+A+ A + L K R + T+ +Q L S+ L R
Sbjct: 910 TQAESALCQMQLETEKERVSL-LETLLQTQKELADASQQLERLR 952
Score = 48.8 bits (111), Expect = 6e-05
Identities = 66/332 (19%), Positives = 142/332 (42%), Gaps = 18/332 (5%)
Query: 317 TKLKSE-VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQ 375
T L +E V KL + + + + DV L++ + + +++ T ++QRQ
Sbjct: 1234 TALSAEAVASALLKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQ 1293
Query: 376 LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
L ++ + + SL E+ E+ R E Q E+Q L NL
Sbjct: 1294 LSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENL 1353
Query: 436 SSSKAKIEQ-ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAV 494
+ A++E + A+V A + D R R +LK+ E + E+ER +A+
Sbjct: 1354 T---AQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKN--EEVESERER---AQAL 1405
Query: 495 KKSLEIEVKNISVRLEEVE--ANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
++ E++V E + + + + L +I+++E + + +K L
Sbjct: 1406 QEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDL 1465
Query: 553 RKKERQL---KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
+K+ +++ +E I + E+ + + L ++++ QK+++ + Q+ E E + T+
Sbjct: 1466 KKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIREPE---KDRETQRN 1522
Query: 610 RFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
+ +L E + + ES ++ + VT
Sbjct: 1523 VLEHQLLELEKKDQMIESQRGQVQDLKKQLVT 1554
Score = 47.6 bits (108), Expect = 1e-04
Identities = 92/473 (19%), Positives = 192/473 (40%), Gaps = 70/473 (14%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMY-KP 201
++++QE ++ +L E+ + + Q+A R + +A+ Q E+ + Q ER+ K
Sbjct: 1784 QQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQ---EQQQAQGQEERVKEKA 1840
Query: 202 DF------QASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPT 255
D QA TL R A+ L E A+ + E + +R
Sbjct: 1841 DALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQE 1900
Query: 256 TCVVRIN-----------TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE 304
++ + E A+ +S+L LKE ++ + L + ++ +
Sbjct: 1901 KALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAAR 1960
Query: 305 I--EQLNARVVEAETKLKS------EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK 356
E L + +A L+ E + + L+ L+ SLD + L++ ++
Sbjct: 1961 ARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALR 2020
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
Q ++ + Y E +QLQ Q+L EE+R E+ +++S+ Q
Sbjct: 2021 IQEGEIQDQDLRYQEDVQQLQ-------------QALAQRDEELRHQQEREQLLEKSLAQ 2067
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIE------QELAIVAADYDEITKELRIADERYQRV 470
+ +E+ + + N+ L + +I +EL + A ++ ELR +R
Sbjct: 2068 RVQENMIQEKQ----NLGLEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLE 2123
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
H + E+ +K+++++ L+ E++ + L + EA I + +
Sbjct: 2124 ALPHSHKTSPMEEQS---LKLDSLEPRLQRELERLQAALRQTEAREI--------EWREK 2172
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+D+ L L + K ++ L++ L+ +++ + +Q+ LQD LE T
Sbjct: 2173 AQDLALSLAQTK----ASVSSLQEVAMFLQASVLERDSEQQR---LQDELELT 2218
Score = 46.4 bits (105), Expect = 3e-04
Identities = 75/350 (21%), Positives = 147/350 (42%), Gaps = 24/350 (6%)
Query: 331 QIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI 390
Q I EL+ D + L + + + SL L++ + +Q+QLQ +Q + ++ +
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSL 1801
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNE-LTVINVNLSSSKAKIEQ---EL 446
QS E + +Q L + +QQ + + RV E + L + +++ EL
Sbjct: 1802 QSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGEL 1861
Query: 447 AIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI--EAVKKSLEIEVKN 504
+ +EL + R Q ++ L E+++ ++ + + +++ E EV+
Sbjct: 1862 QDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVET 1921
Query: 505 ISVRLEEVEANAIVGGKRIISKLEA-RIKDMELELDEE-KRRHAETIK--------ILRK 554
+++ ++A A++ K +LEA R + EE R AE ++ L+
Sbjct: 1922 RALQDSWLQAQAVL--KERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQG 1979
Query: 555 KERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
KE+ L E + + + LQ SL+ + L QEG Q R + ++
Sbjct: 1980 KEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQ 2039
Query: 615 LEAAEDRADVAESNLSLIRAKHR-TFVTTSTVPGSQVYLVQESRALSSER 663
L+ A +A+ + L + R + S Q ++QE + L ER
Sbjct: 2040 LQQA-----LAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGLER 2084
Score = 46.0 bits (104), Expect = 4e-04
Identities = 75/345 (21%), Positives = 153/345 (44%), Gaps = 34/345 (9%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIK--KQSLQL-----TEIQTHYD 370
+LKS+ K +LQ ++TEL L + K N D +K IK ++++++ TE+ H
Sbjct: 269 QLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEA 328
Query: 371 EVQRQLQ-VTLDQYGVAQRRIQSLTGEVEEIR--GNYEQALRVKRSVEQQYEESQTRVNE 427
+ R Q L V + Q + E + I E +L ++ S+ Q+ + Q
Sbjct: 329 SLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGLENSLELESSIFSQF-DYQDADKA 387
Query: 428 LTVINVNLSSSKAKIE---QELA-------IVAADYDEITKELRIADERYQRV------- 470
LT++ L+ + ++ Q+LA ++ +D+ +E + +R Q++
Sbjct: 388 LTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTL 447
Query: 471 --QT-ELKHTVEHLHEEQERIVKI-EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISK 526
QT +L+ V+ L +E+E + K E +++ LE+ ++ + RL V + G +
Sbjct: 448 AGQTVDLQGEVDSLSKERELLQKAREELRQQLEV-LEQEAWRLRRVNVELQLQGDSAQGQ 506
Query: 527 LEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
E + +++ L + E +R + + K+ L E +I E ++I L + L + +
Sbjct: 507 KEEQQEELHLAVRERERLQEMLMGLEAKQSESLSE-LITLREALESIHLEGELLRQEQTE 565
Query: 587 VSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
V+ + + S ++ +L AA + L+L
Sbjct: 566 VTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALAL 610
Score = 44.8 bits (101), Expect = 0.001
Identities = 69/411 (16%), Positives = 167/411 (40%), Gaps = 19/411 (4%)
Query: 222 LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKE 281
L+ L +S+ N ++ +++ ETV + ET+ T + + L+ +K+
Sbjct: 288 LSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKD 347
Query: 282 TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSL 341
+ + I S + S+E+E + + K+ +T ++ L T ++
Sbjct: 348 ITQVMVEEGDNIAQGSGLENSLELESSIFSQFDYQDADKA-LTLVRSVL----TRRRQAV 402
Query: 342 DVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
+ Q+ + Q + + ++++LQ + + L GEV+ +
Sbjct: 403 QDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLS 462
Query: 402 GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELR 461
E + + + QQ E + L +NV L +++ + A +E +EL
Sbjct: 463 KERELLQKAREELRQQLEVLEQEAWRLRRVNVEL-----QLQGDSA--QGQKEEQQEELH 515
Query: 462 IADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGK 521
+A +R+Q L E ++ + +S+ +E + + EV A A+ +
Sbjct: 516 LAVRERERLQEMLMGLEAKQSESLSELITLREALESIHLEGELLRQEQTEVTA-ALARAE 574
Query: 522 RIISKLEARIKDMELELDEEKRRHAETIKI---LRKKERQLKEVIIQCEEDQKNISLLQD 578
+ I++L + ++ E+ + + + + L + L + ++Q EE+ +++ +
Sbjct: 575 QSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRME 634
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+ E+ + + LAE E + + + +L+ AE+ +++L
Sbjct: 635 AAEQARNALQV---DLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADL 682
Score = 34.3 bits (75), Expect = 1.4
Identities = 43/231 (18%), Positives = 103/231 (44%), Gaps = 16/231 (6%)
Query: 406 QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADE 465
Q L + ++ +E+ R EL + KA+++ + ++A + K+ +E
Sbjct: 245 QLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQ----NE 300
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEA--------VKKSLEIEVKNISVRLEEVEANAI 517
Y+++ L+ TVE L +++ EA K SL+ +K+I+ + E E + I
Sbjct: 301 DYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVE-EGDNI 359
Query: 518 VGGKRIISKLEARIKDMELELDEEKRRHAETI--KILRKKERQLKEVIIQCEEDQKNISL 575
G + + LE + + D + A T+ +L ++ + ++++ Q Q+ ++L
Sbjct: 360 AQGSGLENSLELE-SSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNL 418
Query: 576 LQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAE 626
LQ ++ ++ +++L + G + Q E+++ ++ +
Sbjct: 419 LQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQ 469
>AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 62.5 bits (145), Expect = 5e-09
Identities = 99/491 (20%), Positives = 201/491 (40%), Gaps = 29/491 (5%)
Query: 143 KKRMQEIEKELDLYEKEV-NLGSELRQKAAMYRGKSAKAIA-QTLLEESRRNVQNERMYK 200
+++++EI + E EV NL EL ++ YRG + + Q+ LE RR + +
Sbjct: 1171 QEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKE 1230
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
+ + + + + + + + +++ + CD + + E +++T P
Sbjct: 1231 VTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKE 1290
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-----ARVVEA 315
+ E+ Q E +T ++ L + + KQ +E E+ + AR E
Sbjct: 1291 VVQEIL--------QFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEE 1342
Query: 316 ETKLKS-----EVTRIKKK--LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
+++K EV R +++ L+ + + S+DV + L+ +++ + TE++
Sbjct: 1343 LSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQ 1402
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E++R+ Q + QR Q L +E E+ ++ V QQ + Q R + L
Sbjct: 1403 LEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQ-DPQQAREHAL 1461
Query: 429 TVINVNLSSSKAK-IEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQE 486
+ + + + +E EL + + K E++ + VQ E T + + +
Sbjct: 1462 LRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKS 1521
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE---LDEEKR 543
+ + K+ L++EV + RL E+E + K + E K ++LE L E R
Sbjct: 1522 SLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHK-LQLERQNLQLETR 1580
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
R I + + R L+ + + + L E K + L E +
Sbjct: 1581 RLQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRL 1640
Query: 604 SVTRVRRFQRE 614
V+R QRE
Sbjct: 1641 GSVAVKREQRE 1651
Score = 55.2 bits (127), Expect = 7e-07
Identities = 85/430 (19%), Positives = 185/430 (43%), Gaps = 16/430 (3%)
Query: 148 EIEKELDLYEKEVNLGSELRQKAAM--YR-GKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
E+EKEL +E+ + L ++ + Y+ K +A+ T + + V E + +
Sbjct: 1243 EMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDP 1302
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
++ V LS+ + +E + + + ++ E RV+E VVR E
Sbjct: 1303 QTKEEVASLRAKLSEEQKKQVDLERERASQ-EEQIARKEEELSRVKERVVQQEVVRYEEE 1361
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE--IEQLNARVVEAETKLKSE 322
P + + ++Q D L + ++T +E +E+L R +A + + E
Sbjct: 1362 -PGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELE-RERQARREAERE 1419
Query: 323 VTRIKKKLQ-IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
V R++++L ++ E E V + + LQ+ +Q+ + ++ +E Q + Q+
Sbjct: 1420 VQRLQQRLAALEQEEAEAREKVTHTQKVVLQQD-PQQAREHALLRLQLEEEQHRRQLLEG 1478
Query: 382 QYGVAQRRIQSLT-GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+ +R++ +L EV+E E K EQ+ + ++ + E + L +
Sbjct: 1479 ELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVS 1538
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
++E L+ + + +KEL E ++Q E ++L E R+ + +
Sbjct: 1539 RLEARLSELEFHNSKSSKELDFLREENHKLQLER----QNLQLETRRLQSEINMAATETR 1594
Query: 501 EVKNISVRLEEVEANAIVGG-KRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+++N++V ++ + +R + L+ KD +LE+DE ++R ++E L
Sbjct: 1595 DLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKREQRENHL 1654
Query: 560 KEVIIQCEED 569
+ I+ D
Sbjct: 1655 RRSIVVIHPD 1664
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/383 (19%), Positives = 169/383 (44%), Gaps = 21/383 (5%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVY--ILNDSSKQTSIEIEQLNARVVEAETKLK 320
TE+ AI+ L L ++Q ++ V L + + +E + ++ ET+ +
Sbjct: 847 TEVYAINRQRLQNLEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETERR 906
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ--LTEIQTHYDEVQRQLQV 378
++ K Q +I L + ++ K + L+ ++Q E Q + Q+
Sbjct: 907 RQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQL 966
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNY--EQALRVKRSVEQQYEESQTRVNELTVINVNLS 436
++ Q ++++L E + Y ++ LR++ Q E Q R EL +
Sbjct: 967 LQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLR-EELEALRRQKG 1025
Query: 437 SSKAKIEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ +A++ VAA +E ++ + ++ ++ ++Q + + E+ + QE + + ++
Sbjct: 1026 AREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEY-QQLQEDHQRQDQLR 1084
Query: 496 KSLEIEVKNISVRLEEVEAN-AIVGGKRIISKLEARIKDM--ELELDEEKRRHAETIKIL 552
+ E E+ + +L+ +E A+ GK + ++ KD E E+ + R++ +
Sbjct: 1085 EKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKA 1144
Query: 553 RKKERQLKEVI--IQCEEDQKNISLLQDSLE-------KTSQKVSIYKRQLAEQEGMSQQ 603
R +R+ E++ I E++ ++Q+ + K +V+ + +L EQE +
Sbjct: 1145 RASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRG 1204
Query: 604 SVTRVRRFQRELEAAEDRADVAE 626
+ ++R +Q ELEA R E
Sbjct: 1205 AEEQLRSYQSELEALRRRGPQVE 1227
Score = 40.7 bits (91), Expect = 0.016
Identities = 67/373 (17%), Positives = 155/373 (41%), Gaps = 37/373 (9%)
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS-EV 323
L ++ NQ N L E + ++ N Q +++ +L A + + L++
Sbjct: 760 LSQMETKLKNQKNLLDEIASREQEVQKICANSQQYQQAVKDYELEAEKLRSLLDLENGRS 819
Query: 324 TRIKKKLQIQITELELSLD-VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ + K+ ++Q ++ + A I +Q LQ E + Q +++VT +
Sbjct: 820 SHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET 879
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ + R S E +IR ++ +R +E + + +Q + L N ++ +
Sbjct: 880 --LQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLR----NQGPQESVV 933
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
+E+ D + +E +Q++Q L EEQ + + L+ E+
Sbjct: 934 RKEVLKKVPD--------PVLEESFQQLQRTLA-------EEQHK-------NQLLQEEL 971
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + ++L +E GG+ + K RI+ + DE + E + R+K + EV
Sbjct: 972 EALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEV 1031
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++ Q+ ++ L + + +KV+ ++++ + + Q ++ Q + + +
Sbjct: 1032 LLL----QQRVAALAEEKSRAQEKVT--EKEVVKLQN-DPQLEAEYQQLQEDHQRQDQLR 1084
Query: 623 DVAESNLSLIRAK 635
+ E LS ++ K
Sbjct: 1085 EKQEEELSFLQDK 1097
>AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envelope
precursor protein.
Length = 1756
Score = 62.5 bits (145), Expect = 5e-09
Identities = 99/491 (20%), Positives = 201/491 (40%), Gaps = 29/491 (5%)
Query: 143 KKRMQEIEKELDLYEKEV-NLGSELRQKAAMYRGKSAKAIA-QTLLEESRRNVQNERMYK 200
+++++EI + E EV NL EL ++ YRG + + Q+ LE RR + +
Sbjct: 1171 QEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKE 1230
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
+ + + + + + + + +++ + CD + + E +++T P
Sbjct: 1231 VTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKE 1290
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLN-----ARVVEA 315
+ E+ Q E +T ++ L + + KQ +E E+ + AR E
Sbjct: 1291 VVQEIL--------QFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEE 1342
Query: 316 ETKLKS-----EVTRIKKK--LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
+++K EV R +++ L+ + + S+DV + L+ +++ + TE++
Sbjct: 1343 LSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQ 1402
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+E++R+ Q + QR Q L +E E+ ++ V QQ + Q R + L
Sbjct: 1403 LEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQ-DPQQAREHAL 1461
Query: 429 TVINVNLSSSKAK-IEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQE 486
+ + + + +E EL + + K E++ + VQ E T + + +
Sbjct: 1462 LRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKS 1521
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE---LDEEKR 543
+ + K+ L++EV + RL E+E + K + E K ++LE L E R
Sbjct: 1522 SLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHK-LQLERQNLQLETR 1580
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
R I + + R L+ + + + L E K + L E +
Sbjct: 1581 RLQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRL 1640
Query: 604 SVTRVRRFQRE 614
V+R QRE
Sbjct: 1641 GSVAVKREQRE 1651
Score = 54.4 bits (125), Expect = 1e-06
Identities = 84/425 (19%), Positives = 184/425 (43%), Gaps = 16/425 (3%)
Query: 148 EIEKELDLYEKEVNLGSELRQKAAM--YR-GKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
E+EKEL +E+ + L ++ + Y+ K +A+ T + + V E + +
Sbjct: 1243 EMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDP 1302
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
++ V LS+ + +E + + + ++ E RV+E VVR E
Sbjct: 1303 QTKEEVASLRAKLSEEQKKQVDLERERASQ-EEQIARKEEELSRVKERVVQQEVVRYEEE 1361
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIE--IEQLNARVVEAETKLKSE 322
P + + ++Q D L + ++T +E +E+L R +A + + E
Sbjct: 1362 -PGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELE-RERQARREAERE 1419
Query: 323 VTRIKKKLQ-IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD 381
V R++++L ++ E E V + + LQ+ +Q+ + ++ +E Q + Q+
Sbjct: 1420 VQRLQQRLAALEQEEAEAREKVTHTQKVVLQQD-PQQAREHALLRLQLEEEQHRRQLLEG 1478
Query: 382 QYGVAQRRIQSLT-GEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKA 440
+ +R++ +L EV+E E K EQ+ + ++ + E + L +
Sbjct: 1479 ELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVS 1538
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
++E L+ + + +KEL E ++Q E ++L E R+ + +
Sbjct: 1539 RLEARLSELEFHNSKSSKELDFLREENHKLQLER----QNLQLETRRLQSEINMAATETR 1594
Query: 501 EVKNISVRLEEVEANAIVGG-KRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+++N++V ++ + +R + L+ KD +LE+DE ++R ++E L
Sbjct: 1595 DLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKREQRENHL 1654
Query: 560 KEVII 564
+ I+
Sbjct: 1655 RRSIV 1659
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/383 (19%), Positives = 169/383 (44%), Gaps = 21/383 (5%)
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVY--ILNDSSKQTSIEIEQLNARVVEAETKLK 320
TE+ AI+ L L ++Q ++ V L + + +E + ++ ET+ +
Sbjct: 847 TEVYAINRQRLQNLEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETERR 906
Query: 321 SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQ--LTEIQTHYDEVQRQLQV 378
++ K Q +I L + ++ K + L+ ++Q E Q + Q+
Sbjct: 907 RQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQL 966
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNY--EQALRVKRSVEQQYEESQTRVNELTVINVNLS 436
++ Q ++++L E + Y ++ LR++ Q E Q R EL +
Sbjct: 967 LQEELEALQLQLRALEQETRDGGQEYVFKEVLRIEPDRAQADEVLQLR-EELEALRRQKG 1025
Query: 437 SSKAKIEQELAIVAADYDEITK-ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ +A++ VAA +E ++ + ++ ++ ++Q + + E+ + QE + + ++
Sbjct: 1026 AREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEY-QQLQEDHQRQDQLR 1084
Query: 496 KSLEIEVKNISVRLEEVEAN-AIVGGKRIISKLEARIKDM--ELELDEEKRRHAETIKIL 552
+ E E+ + +L+ +E A+ GK + ++ KD E E+ + R++ +
Sbjct: 1085 EKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKA 1144
Query: 553 RKKERQLKEVI--IQCEEDQKNISLLQDSLE-------KTSQKVSIYKRQLAEQEGMSQQ 603
R +R+ E++ I E++ ++Q+ + K +V+ + +L EQE +
Sbjct: 1145 RASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRG 1204
Query: 604 SVTRVRRFQRELEAAEDRADVAE 626
+ ++R +Q ELEA R E
Sbjct: 1205 AEEQLRSYQSELEALRRRGPQVE 1227
Score = 40.7 bits (91), Expect = 0.016
Identities = 67/373 (17%), Positives = 155/373 (41%), Gaps = 37/373 (9%)
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS-EV 323
L ++ NQ N L E + ++ N Q +++ +L A + + L++
Sbjct: 760 LSQMETKLKNQKNLLDEIASREQEVQKICANSQQYQQAVKDYELEAEKLRSLLDLENGRS 819
Query: 324 TRIKKKLQIQITELELSLD-VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ + K+ ++Q ++ + A I +Q LQ E + Q +++VT +
Sbjct: 820 SHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET 879
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+ + R S E +IR ++ +R +E + + +Q + L N ++ +
Sbjct: 880 --LQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLR----NQGPQESVV 933
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
+E+ D + +E +Q++Q L EEQ + + L+ E+
Sbjct: 934 RKEVLKKVPD--------PVLEESFQQLQRTLA-------EEQHK-------NQLLQEEL 971
Query: 503 KNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEV 562
+ + ++L +E GG+ + K RI+ + DE + E + R+K + EV
Sbjct: 972 EALQLQLRALEQETRDGGQEYVFKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEV 1031
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRA 622
++ Q+ ++ L + + +KV+ ++++ + + Q ++ Q + + +
Sbjct: 1032 LLL----QQRVAALAEEKSRAQEKVT--EKEVVKLQN-DPQLEAEYQQLQEDHQRQDQLR 1084
Query: 623 DVAESNLSLIRAK 635
+ E LS ++ K
Sbjct: 1085 EKQEEELSFLQDK 1097
>AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golgin
subfamily a, 4 variant protein.
Length = 1310
Score = 62.5 bits (145), Expect = 5e-09
Identities = 84/345 (24%), Positives = 153/345 (44%), Gaps = 23/345 (6%)
Query: 273 LNQLNEL-KETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKK 329
+NQL L KE K + ++ N + K++ E++Q +A++ + +S K
Sbjct: 789 INQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQSYQSATHEQTKA 847
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQ----LTEIQTHYDEVQRQLQVTLDQYGV 385
+ Q+ +L+ L I L K + + Q TE+ H +VQ +Q Q
Sbjct: 848 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 907
Query: 386 AQRRIQSLTGEVEEIR---GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
+++++SLT +V E + GN EQ + VE++ Q R + I + AK
Sbjct: 908 MEQKVKSLT-QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAK- 965
Query: 443 EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEV 502
E + I+ +Y+ K E+ ++ E++ T++ +QE +K E +LE+
Sbjct: 966 EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 1025
Query: 503 KNISVR---LEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA-ETIKILRKKERQ 558
K LE +AN+ G +S+LE K+ L E RR + I I KK Q
Sbjct: 1026 KEKQFNAKMLEMAQANS-AGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQ 1084
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
E + + E Q + + + + QK+ ++ E+E M+++
Sbjct: 1085 QAEELQEIHEIQ--LQEKEQEVAELKQKILLFG---CEKEEMNKE 1124
Score = 61.7 bits (143), Expect = 8e-09
Identities = 82/453 (18%), Positives = 196/453 (43%), Gaps = 26/453 (5%)
Query: 149 IEKELDLYEKEVN--LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
+++EL ++EV + ++ A + K +A+ E +++ ER ++ + +
Sbjct: 486 LQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVA 545
Query: 207 RTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETV-RVRETSPTTCVVRINTEL 265
+Y +S+ K ES A+ + + +TE+ ++R+ R T +
Sbjct: 546 LEKSQSEYLKISQE---KEQQESLALEELELQKKAILTESENKLRDLQQEAETYR--TRI 600
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
+++S L E K K DL+V++ + +K + E E+ +
Sbjct: 601 LELESSLEKSLQENKNQSK---DLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDAL 657
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
+KLQ+ + + ++ + ++T+ K + Q H +E+ + TL++ V
Sbjct: 658 WTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII--FQAHIEEMNEK---TLEKLDV 712
Query: 386 AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQ 444
Q ++SL+ E+ E+ L+ + +E++ + + +++ + + K +Q
Sbjct: 713 KQTELESLSSELSEV-------LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ 765
Query: 445 ELAIVAADYD-EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
++ + +++ I + + ++ +++ LK +HL E Q + +EA K E E++
Sbjct: 766 QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQ 825
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
S +L+ ++ ++ + E + + LD E R T K + + E Q K+V
Sbjct: 826 QASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLT-KQVAEVEAQKKDVC 884
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
+ + + + L LEK + ++ + L +
Sbjct: 885 TELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 917
Score = 56.4 bits (130), Expect = 3e-07
Identities = 97/548 (17%), Positives = 232/548 (42%), Gaps = 57/548 (10%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+R+QE+EK DL+ E L ++LR + + + + E R+ + M + +
Sbjct: 356 ERLQELEKIKDLHMAEKTKLITQLRDAKNLIE-QLEQDKGMVIAETKRQMHETLEMKEEE 414
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
R+ + + T + K E A + ++ T + E + ++
Sbjct: 415 IAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALS-----TAQKTEEARRKLKAEMD 469
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
++ I+ + + L++ + + V ++ SS++ ++++L+ E +L +
Sbjct: 470 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLH------EKELARK 523
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ KKLQ + E + + VA + + I ++ Q + E+Q++ +T
Sbjct: 524 EQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILT--- 580
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKI 442
++ +++ L E E R + L ++ S+E+ +E++ + +L V +L + K K
Sbjct: 581 --ESENKLRDLQQEAETYR---TRILELESSLEKSLQENKNQSKDLAV---HLEAEKNKH 632
Query: 443 EQELAIVAADYDEITKELRIADERY---------QRVQTELKHTVEHLHEEQERIVKIEA 493
+E+ ++ + + L+ + Q+ QTE++ E +E+E ++K +
Sbjct: 633 NKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKE 692
Query: 494 V----------KKSLE-IEVKNISVRLEEVEANAIVGGKRIISKLEARIKD--------M 534
+ +K+LE ++VK + E + ++ + + + + +KD +
Sbjct: 693 IIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL 752
Query: 535 ELELDEEKRRHAETI-KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK----VSI 589
E ++DE+K H + + I+++ E ++ ++ + LL +K ++ V
Sbjct: 753 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVEN 812
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQ 649
+ + EG QQ+ ++ FQ A ++ E L+ ++ K T + Q
Sbjct: 813 LEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQ 872
Query: 650 VYLVQESR 657
V V+ +
Sbjct: 873 VAEVEAQK 880
Score = 32.3 bits (70), Expect = 5.6
Identities = 69/376 (18%), Positives = 153/376 (40%), Gaps = 24/376 (6%)
Query: 146 MQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ- 204
MQ++EK+ E++V +++ + K + Q L+E+ +Q K + +
Sbjct: 898 MQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEI 957
Query: 205 -ASRTLVNRDYTN-LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRIN 262
+ D + L++ K + K M + E + ET++ + ++
Sbjct: 958 LTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKE-MQETLKKKLLDQEA---KLK 1013
Query: 263 TELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSE 322
EL +N+ L EL + KQF+ + + +S S + +L E L +E
Sbjct: 1014 KEL---ENTAL----ELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESL-TE 1065
Query: 323 VTRIKKKLQIQITELELSLDVANKTNI-DLQKTIKKQSL-----QLTEIQTHYDEVQRQL 376
V R + I I E +L+ I ++Q K+Q + ++ +E+ +++
Sbjct: 1066 VHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEI 1125
Query: 377 QVTLDQYGVAQ-RRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
L + GV Q + L ++++ + + + ++ E+ + +N+ N L
Sbjct: 1126 -TWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFL 1184
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI-EAV 494
+++ E+T +L+ DE +Q +++ + + + L ++ K+ E +
Sbjct: 1185 QEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1244
Query: 495 KKSLEIEVKNISVRLE 510
L+I K LE
Sbjct: 1245 AIQLDICCKKTEALLE 1260
Score = 32.3 bits (70), Expect = 5.6
Identities = 44/230 (19%), Positives = 95/230 (41%), Gaps = 10/230 (4%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+ + ++IE +++ +E+N + +K + + + I + L+E + V +
Sbjct: 1053 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKIL 1112
Query: 202 DFQASRTLVNRDYTNLSKNVLAK--ALMESKAMNSCDSRVTESITETVRVRETSPTTCVV 259
F + +N++ T L + + + L E + S S+ + + V
Sbjct: 1113 LFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEV 1172
Query: 260 RINTELPAIDNSYL-NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+N L +N++L QL ELK ++ D V L K T E + L + ++
Sbjct: 1173 DLNKSLK--ENTFLQEQLVELKMLAEE-DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKS 1229
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
L+ + KK + EL + LD+ K L + + + ++ +T+
Sbjct: 1230 LEDKSLEFKKLSE----ELAIQLDICCKKTEALLEAKTNELINISSSKTN 1275
>AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 62.1 bits (144), Expect = 6e-09
Identities = 111/529 (20%), Positives = 241/529 (45%), Gaps = 62/529 (11%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
K++ ++EL L EK+ + L E++Q + Y AIA+ +++S+ Q E++ K
Sbjct: 910 KQIVHFQQELSLSEKKNLTLSKEVQQIQSNYD----IAIAELHVQKSKNQEQEEKIMKLS 965
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVRETSPTTCVVR 260
+ R TN NV LM +K + + DS S + + +R+ S +
Sbjct: 966 NEIETA--TRSITN---NVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDN 1020
Query: 261 I-NTELPAIDNSYL-------------NQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
+ NT+L + N YL N+ N +++ + I+ SSK+ S +IE
Sbjct: 1021 LPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKK-SHQIE 1079
Query: 307 QLNARV--VEAETK-LKSEVTRIKKK-----------LQIQITELELSLDVANKT-NIDL 351
+L ++ ++AE K K E R+K+K + I +L+ L N T ++ +
Sbjct: 1080 ELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQI 1139
Query: 352 QKTIK-KQSL-QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALR 409
Q ++ K++L +LT+ T Y ++L+ L+ V L ++ E L+
Sbjct: 1140 QHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILE---KESIILK 1196
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR 469
++R++++ E Q V +NV + K+++E+ + + ++ L++ +E +
Sbjct: 1197 LERNLKEFQEHLQDSVKNTKDLNVK----ELKLKEEITQLTNNLQDMKHLLQLKEEEEET 1252
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLE 528
+ E + E L R ++A + E + ++ +L + + K + + + E
Sbjct: 1253 NRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDE 1312
Query: 529 ARIKDMEL-ELDEEKRRHAETIKILRKKERQLKE---------VIIQCEEDQKNISLLQD 578
++ +++ EL+++K + ++ + + ++ +QLKE I Q E K++++ +
Sbjct: 1313 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1372
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES 627
+E + ++ EQ+ + + + V R ELE +++ + E+
Sbjct: 1373 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLET 1421
Score = 59.7 bits (138), Expect = 3e-08
Identities = 71/304 (23%), Positives = 148/304 (48%), Gaps = 32/304 (10%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
E L A ++ E +LK+E K +L QI + L ++ K N+ L K ++ +I
Sbjct: 885 EGLRAFLLTIENELKNEKEE-KAELNKQIVHFQQELSLSEKKNLTLSKEVQ-------QI 936
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQALRVKRSVEQ-QYEE 420
Q++YD +L V + + +I L+ E+E I N Q + +++ + +
Sbjct: 937 QSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLD 996
Query: 421 SQTRVNELTVINVNLSSSKAKIEQ----ELAIVAADY--DEITKELRIADERYQRVQTEL 474
S ++++ + ++N+ S+ ++ + +L ++ DY + KE RI + +
Sbjct: 997 SVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR---ENSF 1053
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
++E + EE + IVK + KKS +IE + ++E+++A + G K R+K+
Sbjct: 1054 HSSIEAIWEECKEIVKASS-KKSHQIE--ELEQQIEKLQAE-VKGYK----DENNRLKEK 1105
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
E + ++ + ET+ K+E Q K V + + +++ + +L + +Q V+ YK ++
Sbjct: 1106 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQ--IQHVVEGKRALSELTQGVTCYKAKI 1163
Query: 595 AEQE 598
E E
Sbjct: 1164 KELE 1167
Score = 57.6 bits (133), Expect = 1e-07
Identities = 87/407 (21%), Positives = 185/407 (45%), Gaps = 34/407 (8%)
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVT---ESITETVRV--RETSPTTCVVRINT 263
L+ DY +SK V + E NS S + E E V+ +++ + +
Sbjct: 1028 LLGNDYL-VSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIE 1086
Query: 264 ELPAIDNSYLNQLNELKETV-KQFDDLS------VYILNDSSKQTSIEIEQLNARVVEAE 316
+L A Y ++ N LKE K DDL + L + ++ ++ ++ VVE +
Sbjct: 1087 KLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK 1146
Query: 317 TKLKSEVTRIKKKLQIQITELELSLD---VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
L SE+T+ + +I ELE L+ V + L++ I ++ + +++ + E Q
Sbjct: 1147 RAL-SELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQ 1205
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
LQ ++ + L E+ ++ N + +K ++ + EE +T E +
Sbjct: 1206 EHLQDSVKNTKDLNVKELKLKEEITQLTNNLQD---MKHLLQLKEEEEETNRQETEKLKE 1262
Query: 434 NLSSSKAK---IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
LS+S A+ ++ +L DY ++ ++L A ++ ++VQ E+ + + +I +
Sbjct: 1263 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1322
Query: 491 IEAVKK--SLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEAR---IKDMELELD 539
+E K S E+++K +++ + + N AI +R L + I+DM + L+
Sbjct: 1323 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE 1382
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
E+++ E ++L K +++ + + E+ ++ + L+ + S K
Sbjct: 1383 EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNK 1429
Score = 35.5 bits (78), Expect = 0.61
Identities = 113/558 (20%), Positives = 231/558 (41%), Gaps = 65/558 (11%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q+ ++ DL KE+ L E+ Q + K + Q EE N Q K
Sbjct: 1205 QEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQ--DMKHLLQLKEEEEETNRQETEKLKE 1262
Query: 202 DFQASRTLVNR----------DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVR- 250
+ AS DY +L K L A + K + + V + +R++
Sbjct: 1263 ELSASSARTQNLKADLQRKEEDYADL-KEKLTDAKKQIKQVQK-EVSVMRDEDKLLRIKI 1320
Query: 251 ---ETSPTTCVVRINTELPAIDNSYLNQLNELK--ETVKQFD----DLSVY--ILND--- 296
E C ++ + I QLN K E ++Q++ DL+V I+ D
Sbjct: 1321 NELEKKKNQCSQELDMKQRTIQQ-LKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRM 1379
Query: 297 ---SSKQTSIEIEQ-LNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQ 352
+QT +E +Q L A++ E E +L +E+ + K+K T+ + ++ N D+
Sbjct: 1380 TLEEQEQTQVEQDQVLEAKLEEVE-RLATELEKWKEKCNDLETKNNQRSNKEHENNTDVL 1438
Query: 353 KTIKKQSLQLTEIQTHYD-EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVK 411
+ +L E + Y+ + ++ L+ + A+ E+++ + E+ + +
Sbjct: 1439 GKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQ 1498
Query: 412 RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADY---DEITKELRIADERY 467
+E + + ++L A +E +L A+++++ +EI + RI E
Sbjct: 1499 NEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISET- 1557
Query: 468 QRVQTELKH-TVEHLHEEQERIVKIEAVKKSLEI---EVKNISVRLEEVEANAIVGGKRI 523
+++T++ + + ++ E + S EI ++++ SV L+ E +
Sbjct: 1558 SKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTENDQSTR 1617
Query: 524 ISKLEARIKDMELELDEEKRRH-----AETIKI---LRKKERQLKEVIIQCEEDQKN--- 572
K E I+ L+ ++ +H T+KI ++K +++E +++C E++KN
Sbjct: 1618 FPKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKC-ENKKNATP 1676
Query: 573 -------ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR-ADV 624
IS ++S K QKV+I SQ S+ V ++ E + D
Sbjct: 1677 RTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEGTLQKFGDF 1736
Query: 625 AESNLSLIRAKHRTFVTT 642
+ + S++++K + + T
Sbjct: 1737 LQHSPSILQSKAKKIIET 1754
>AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 62.1 bits (144), Expect = 6e-09
Identities = 111/529 (20%), Positives = 241/529 (45%), Gaps = 62/529 (11%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
K++ ++EL L EK+ + L E++Q + Y AIA+ +++S+ Q E++ K
Sbjct: 870 KQIVHFQQELSLSEKKNLTLSKEVQQIQSNYD----IAIAELHVQKSKNQEQEEKIMKLS 925
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVRETSPTTCVVR 260
+ R TN NV LM +K + + DS S + + +R+ S +
Sbjct: 926 NEIETA--TRSITN---NVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDN 980
Query: 261 I-NTELPAIDNSYL-------------NQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
+ NT+L + N YL N+ N +++ + I+ SSK+ S +IE
Sbjct: 981 LPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKK-SHQIE 1039
Query: 307 QLNARV--VEAETK-LKSEVTRIKKK-----------LQIQITELELSLDVANKT-NIDL 351
+L ++ ++AE K K E R+K+K + I +L+ L N T ++ +
Sbjct: 1040 ELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQI 1099
Query: 352 QKTIK-KQSL-QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALR 409
Q ++ K++L +LT+ T Y ++L+ L+ V L ++ E L+
Sbjct: 1100 QHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILE---KESIILK 1156
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR 469
++R++++ E Q V +NV + K+++E+ + + ++ L++ +E +
Sbjct: 1157 LERNLKEFQEHLQDSVKNTKDLNVK----ELKLKEEITQLTNNLQDMKHLLQLKEEEEET 1212
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLE 528
+ E + E L R ++A + E + ++ +L + + K + + + E
Sbjct: 1213 NRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDE 1272
Query: 529 ARIKDMEL-ELDEEKRRHAETIKILRKKERQLKE---------VIIQCEEDQKNISLLQD 578
++ +++ EL+++K + ++ + + ++ +QLKE I Q E K++++ +
Sbjct: 1273 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1332
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES 627
+E + ++ EQ+ + + + V R ELE +++ + E+
Sbjct: 1333 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLET 1381
Score = 59.7 bits (138), Expect = 3e-08
Identities = 71/304 (23%), Positives = 148/304 (48%), Gaps = 32/304 (10%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
E L A ++ E +LK+E K +L QI + L ++ K N+ L K ++ +I
Sbjct: 845 EGLRAFLLTIENELKNEKEE-KAELNKQIVHFQQELSLSEKKNLTLSKEVQ-------QI 896
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQALRVKRSVEQ-QYEE 420
Q++YD +L V + + +I L+ E+E I N Q + +++ + +
Sbjct: 897 QSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLD 956
Query: 421 SQTRVNELTVINVNLSSSKAKIEQ----ELAIVAADY--DEITKELRIADERYQRVQTEL 474
S ++++ + ++N+ S+ ++ + +L ++ DY + KE RI + +
Sbjct: 957 SVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR---ENSF 1013
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
++E + EE + IVK + KKS +IE + ++E+++A + G K R+K+
Sbjct: 1014 HSSIEAIWEECKEIVKASS-KKSHQIE--ELEQQIEKLQAE-VKGYK----DENNRLKEK 1065
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
E + ++ + ET+ K+E Q K V + + +++ + +L + +Q V+ YK ++
Sbjct: 1066 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQ--IQHVVEGKRALSELTQGVTCYKAKI 1123
Query: 595 AEQE 598
E E
Sbjct: 1124 KELE 1127
Score = 57.6 bits (133), Expect = 1e-07
Identities = 87/407 (21%), Positives = 185/407 (45%), Gaps = 34/407 (8%)
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVT---ESITETVRV--RETSPTTCVVRINT 263
L+ DY +SK V + E NS S + E E V+ +++ + +
Sbjct: 988 LLGNDYL-VSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIE 1046
Query: 264 ELPAIDNSYLNQLNELKETV-KQFDDLS------VYILNDSSKQTSIEIEQLNARVVEAE 316
+L A Y ++ N LKE K DDL + L + ++ ++ ++ VVE +
Sbjct: 1047 KLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK 1106
Query: 317 TKLKSEVTRIKKKLQIQITELELSLD---VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
L SE+T+ + +I ELE L+ V + L++ I ++ + +++ + E Q
Sbjct: 1107 RAL-SELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQ 1165
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
LQ ++ + L E+ ++ N + +K ++ + EE +T E +
Sbjct: 1166 EHLQDSVKNTKDLNVKELKLKEEITQLTNNLQD---MKHLLQLKEEEEETNRQETEKLKE 1222
Query: 434 NLSSSKAK---IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
LS+S A+ ++ +L DY ++ ++L A ++ ++VQ E+ + + +I +
Sbjct: 1223 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1282
Query: 491 IEAVKK--SLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEAR---IKDMELELD 539
+E K S E+++K +++ + + N AI +R L + I+DM + L+
Sbjct: 1283 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE 1342
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
E+++ E ++L K +++ + + E+ ++ + L+ + S K
Sbjct: 1343 EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNK 1389
Score = 35.5 bits (78), Expect = 0.61
Identities = 113/558 (20%), Positives = 231/558 (41%), Gaps = 65/558 (11%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q+ ++ DL KE+ L E+ Q + K + Q EE N Q K
Sbjct: 1165 QEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQ--DMKHLLQLKEEEEETNRQETEKLKE 1222
Query: 202 DFQASRTLVNR----------DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVR- 250
+ AS DY +L K L A + K + + V + +R++
Sbjct: 1223 ELSASSARTQNLKADLQRKEEDYADL-KEKLTDAKKQIKQVQK-EVSVMRDEDKLLRIKI 1280
Query: 251 ---ETSPTTCVVRINTELPAIDNSYLNQLNELK--ETVKQFD----DLSVY--ILND--- 296
E C ++ + I QLN K E ++Q++ DL+V I+ D
Sbjct: 1281 NELEKKKNQCSQELDMKQRTIQQ-LKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRM 1339
Query: 297 ---SSKQTSIEIEQ-LNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQ 352
+QT +E +Q L A++ E E +L +E+ + K+K T+ + ++ N D+
Sbjct: 1340 TLEEQEQTQVEQDQVLEAKLEEVE-RLATELEKWKEKCNDLETKNNQRSNKEHENNTDVL 1398
Query: 353 KTIKKQSLQLTEIQTHYD-EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVK 411
+ +L E + Y+ + ++ L+ + A+ E+++ + E+ + +
Sbjct: 1399 GKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQ 1458
Query: 412 RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADY---DEITKELRIADERY 467
+E + + ++L A +E +L A+++++ +EI + RI E
Sbjct: 1459 NEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISET- 1517
Query: 468 QRVQTELKH-TVEHLHEEQERIVKIEAVKKSLEI---EVKNISVRLEEVEANAIVGGKRI 523
+++T++ + + ++ E + S EI ++++ SV L+ E +
Sbjct: 1518 SKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTENDQSTR 1577
Query: 524 ISKLEARIKDMELELDEEKRRH-----AETIKI---LRKKERQLKEVIIQCEEDQKN--- 572
K E I+ L+ ++ +H T+KI ++K +++E +++C E++KN
Sbjct: 1578 FPKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKC-ENKKNATP 1636
Query: 573 -------ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR-ADV 624
IS ++S K QKV+I SQ S+ V ++ E + D
Sbjct: 1637 RTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEGTLQKFGDF 1696
Query: 625 AESNLSLIRAKHRTFVTT 642
+ + S++++K + + T
Sbjct: 1697 LQHSPSILQSKAKKIIET 1714
>AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 62.1 bits (144), Expect = 6e-09
Identities = 111/529 (20%), Positives = 241/529 (45%), Gaps = 62/529 (11%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
K++ ++EL L EK+ + L E++Q + Y AIA+ +++S+ Q E++ K
Sbjct: 870 KQIVHFQQELSLSEKKNLTLSKEVQQIQSNYD----IAIAELHVQKSKNQEQEEKIMKLS 925
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVRETSPTTCVVR 260
+ R TN NV LM +K + + DS S + + +R+ S +
Sbjct: 926 NEIETA--TRSITN---NVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDN 980
Query: 261 I-NTELPAIDNSYL-------------NQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
+ NT+L + N YL N+ N +++ + I+ SSK+ S +IE
Sbjct: 981 LPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKK-SHQIE 1039
Query: 307 QLNARV--VEAETK-LKSEVTRIKKK-----------LQIQITELELSLDVANKT-NIDL 351
+L ++ ++AE K K E R+K+K + I +L+ L N T ++ +
Sbjct: 1040 ELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQI 1099
Query: 352 QKTIK-KQSL-QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALR 409
Q ++ K++L +LT+ T Y ++L+ L+ V L ++ E L+
Sbjct: 1100 QHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILE---KESIILK 1156
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR 469
++R++++ E Q V +NV + K+++E+ + + ++ L++ +E +
Sbjct: 1157 LERNLKEFQEHLQDSVKNTKDLNVK----ELKLKEEITQLTNNLQDMKHLLQLKEEEEET 1212
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLE 528
+ E + E L R ++A + E + ++ +L + + K + + + E
Sbjct: 1213 NRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDE 1272
Query: 529 ARIKDMEL-ELDEEKRRHAETIKILRKKERQLKE---------VIIQCEEDQKNISLLQD 578
++ +++ EL+++K + ++ + + ++ +QLKE I Q E K++++ +
Sbjct: 1273 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1332
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES 627
+E + ++ EQ+ + + + V R ELE +++ + E+
Sbjct: 1333 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLET 1381
Score = 59.7 bits (138), Expect = 3e-08
Identities = 71/304 (23%), Positives = 148/304 (48%), Gaps = 32/304 (10%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
E L A ++ E +LK+E K +L QI + L ++ K N+ L K ++ +I
Sbjct: 845 EGLRAFLLTIENELKNEKEE-KAELNKQIVHFQQELSLSEKKNLTLSKEVQ-------QI 896
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQALRVKRSVEQ-QYEE 420
Q++YD +L V + + +I L+ E+E I N Q + +++ + +
Sbjct: 897 QSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLD 956
Query: 421 SQTRVNELTVINVNLSSSKAKIEQ----ELAIVAADY--DEITKELRIADERYQRVQTEL 474
S ++++ + ++N+ S+ ++ + +L ++ DY + KE RI + +
Sbjct: 957 SVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR---ENSF 1013
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
++E + EE + IVK + KKS +IE + ++E+++A + G K R+K+
Sbjct: 1014 HSSIEAIWEECKEIVKASS-KKSHQIE--ELEQQIEKLQAE-VKGYK----DENNRLKEK 1065
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
E + ++ + ET+ K+E Q K V + + +++ + +L + +Q V+ YK ++
Sbjct: 1066 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQ--IQHVVEGKRALSELTQGVTCYKAKI 1123
Query: 595 AEQE 598
E E
Sbjct: 1124 KELE 1127
Score = 57.6 bits (133), Expect = 1e-07
Identities = 87/407 (21%), Positives = 185/407 (45%), Gaps = 34/407 (8%)
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVT---ESITETVRV--RETSPTTCVVRINT 263
L+ DY +SK V + E NS S + E E V+ +++ + +
Sbjct: 988 LLGNDYL-VSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIE 1046
Query: 264 ELPAIDNSYLNQLNELKETV-KQFDDLS------VYILNDSSKQTSIEIEQLNARVVEAE 316
+L A Y ++ N LKE K DDL + L + ++ ++ ++ VVE +
Sbjct: 1047 KLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK 1106
Query: 317 TKLKSEVTRIKKKLQIQITELELSLD---VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
L SE+T+ + +I ELE L+ V + L++ I ++ + +++ + E Q
Sbjct: 1107 RAL-SELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQ 1165
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
LQ ++ + L E+ ++ N + +K ++ + EE +T E +
Sbjct: 1166 EHLQDSVKNTKDLNVKELKLKEEITQLTNNLQD---MKHLLQLKEEEEETNRQETEKLKE 1222
Query: 434 NLSSSKAK---IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
LS+S A+ ++ +L DY ++ ++L A ++ ++VQ E+ + + +I +
Sbjct: 1223 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1282
Query: 491 IEAVKK--SLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEAR---IKDMELELD 539
+E K S E+++K +++ + + N AI +R L + I+DM + L+
Sbjct: 1283 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE 1342
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
E+++ E ++L K +++ + + E+ ++ + L+ + S K
Sbjct: 1343 EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNK 1389
Score = 35.5 bits (78), Expect = 0.61
Identities = 113/558 (20%), Positives = 231/558 (41%), Gaps = 65/558 (11%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q+ ++ DL KE+ L E+ Q + K + Q EE N Q K
Sbjct: 1165 QEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQ--DMKHLLQLKEEEEETNRQETEKLKE 1222
Query: 202 DFQASRTLVNR----------DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVR- 250
+ AS DY +L K L A + K + + V + +R++
Sbjct: 1223 ELSASSARTQNLKADLQRKEEDYADL-KEKLTDAKKQIKQVQK-EVSVMRDEDKLLRIKI 1280
Query: 251 ---ETSPTTCVVRINTELPAIDNSYLNQLNELK--ETVKQFD----DLSVY--ILND--- 296
E C ++ + I QLN K E ++Q++ DL+V I+ D
Sbjct: 1281 NELEKKKNQCSQELDMKQRTIQQ-LKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRM 1339
Query: 297 ---SSKQTSIEIEQ-LNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQ 352
+QT +E +Q L A++ E E +L +E+ + K+K T+ + ++ N D+
Sbjct: 1340 TLEEQEQTQVEQDQVLEAKLEEVE-RLATELEKWKEKCNDLETKNNQRSNKEHENNTDVL 1398
Query: 353 KTIKKQSLQLTEIQTHYD-EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVK 411
+ +L E + Y+ + ++ L+ + A+ E+++ + E+ + +
Sbjct: 1399 GKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQ 1458
Query: 412 RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADY---DEITKELRIADERY 467
+E + + ++L A +E +L A+++++ +EI + RI E
Sbjct: 1459 NEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISET- 1517
Query: 468 QRVQTELKH-TVEHLHEEQERIVKIEAVKKSLEI---EVKNISVRLEEVEANAIVGGKRI 523
+++T++ + + ++ E + S EI ++++ SV L+ E +
Sbjct: 1518 SKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTENDQSTR 1577
Query: 524 ISKLEARIKDMELELDEEKRRH-----AETIKI---LRKKERQLKEVIIQCEEDQKN--- 572
K E I+ L+ ++ +H T+KI ++K +++E +++C E++KN
Sbjct: 1578 FPKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKC-ENKKNATP 1636
Query: 573 -------ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR-ADV 624
IS ++S K QKV+I SQ S+ V ++ E + D
Sbjct: 1637 RTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEGTLQKFGDF 1696
Query: 625 AESNLSLIRAKHRTFVTT 642
+ + S++++K + + T
Sbjct: 1697 LQHSPSILQSKAKKIIET 1714
>AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 62.1 bits (144), Expect = 6e-09
Identities = 111/529 (20%), Positives = 241/529 (45%), Gaps = 62/529 (11%)
Query: 144 KRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
K++ ++EL L EK+ + L E++Q + Y AIA+ +++S+ Q E++ K
Sbjct: 910 KQIVHFQQELSLSEKKNLTLSKEVQQIQSNYD----IAIAELHVQKSKNQEQEEKIMKLS 965
Query: 203 FQASRTLVNRDYTNLSKNVLAKALMESKA--MNSCDSRVTESITETVRVRETSPTTCVVR 260
+ R TN NV LM +K + + DS S + + +R+ S +
Sbjct: 966 NEIETA--TRSITN---NVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDN 1020
Query: 261 I-NTELPAIDNSYL-------------NQLNELKETVKQFDDLSVYILNDSSKQTSIEIE 306
+ NT+L + N YL N+ N +++ + I+ SSK+ S +IE
Sbjct: 1021 LPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKK-SHQIE 1079
Query: 307 QLNARV--VEAETK-LKSEVTRIKKK-----------LQIQITELELSLDVANKT-NIDL 351
+L ++ ++AE K K E R+K+K + I +L+ L N T ++ +
Sbjct: 1080 ELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQI 1139
Query: 352 QKTIK-KQSL-QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALR 409
Q ++ K++L +LT+ T Y ++L+ L+ V L ++ E L+
Sbjct: 1140 QHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILE---KESIILK 1196
Query: 410 VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR 469
++R++++ E Q V +NV + K+++E+ + + ++ L++ +E +
Sbjct: 1197 LERNLKEFQEHLQDSVKNTKDLNVK----ELKLKEEITQLTNNLQDMKHLLQLKEEEEET 1252
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRI-ISKLE 528
+ E + E L R ++A + E + ++ +L + + K + + + E
Sbjct: 1253 NRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDE 1312
Query: 529 ARIKDMEL-ELDEEKRRHAETIKILRKKERQLKE---------VIIQCEEDQKNISLLQD 578
++ +++ EL+++K + ++ + + ++ +QLKE I Q E K++++ +
Sbjct: 1313 DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK 1372
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES 627
+E + ++ EQ+ + + + V R ELE +++ + E+
Sbjct: 1373 IIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLET 1421
Score = 59.7 bits (138), Expect = 3e-08
Identities = 71/304 (23%), Positives = 148/304 (48%), Gaps = 32/304 (10%)
Query: 306 EQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
E L A ++ E +LK+E K +L QI + L ++ K N+ L K ++ +I
Sbjct: 885 EGLRAFLLTIENELKNEKEE-KAELNKQIVHFQQELSLSEKKNLTLSKEVQ-------QI 936
Query: 366 QTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVE----EIRGNYEQALRVKRSVEQ-QYEE 420
Q++YD +L V + + +I L+ E+E I N Q + +++ + +
Sbjct: 937 QSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLD 996
Query: 421 SQTRVNELTVINVNLSSSKAKIEQ----ELAIVAADY--DEITKELRIADERYQRVQTEL 474
S ++++ + ++N+ S+ ++ + +L ++ DY + KE RI + +
Sbjct: 997 SVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR---ENSF 1053
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
++E + EE + IVK + KKS +IE + ++E+++A + G K R+K+
Sbjct: 1054 HSSIEAIWEECKEIVKASS-KKSHQIE--ELEQQIEKLQAE-VKGYK----DENNRLKEK 1105
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQL 594
E + ++ + ET+ K+E Q K V + + +++ + +L + +Q V+ YK ++
Sbjct: 1106 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQ--IQHVVEGKRALSELTQGVTCYKAKI 1163
Query: 595 AEQE 598
E E
Sbjct: 1164 KELE 1167
Score = 57.6 bits (133), Expect = 1e-07
Identities = 87/407 (21%), Positives = 185/407 (45%), Gaps = 34/407 (8%)
Query: 209 LVNRDYTNLSKNVLAKALMESKAMNSCDSRVT---ESITETVRV--RETSPTTCVVRINT 263
L+ DY +SK V + E NS S + E E V+ +++ + +
Sbjct: 1028 LLGNDYL-VSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIE 1086
Query: 264 ELPAIDNSYLNQLNELKETV-KQFDDLS------VYILNDSSKQTSIEIEQLNARVVEAE 316
+L A Y ++ N LKE K DDL + L + ++ ++ ++ VVE +
Sbjct: 1087 KLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK 1146
Query: 317 TKLKSEVTRIKKKLQIQITELELSLD---VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
L SE+T+ + +I ELE L+ V + L++ I ++ + +++ + E Q
Sbjct: 1147 RAL-SELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQ 1205
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
LQ ++ + L E+ ++ N + +K ++ + EE +T E +
Sbjct: 1206 EHLQDSVKNTKDLNVKELKLKEEITQLTNNLQD---MKHLLQLKEEEEETNRQETEKLKE 1262
Query: 434 NLSSSKAK---IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
LS+S A+ ++ +L DY ++ ++L A ++ ++VQ E+ + + +I +
Sbjct: 1263 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1322
Query: 491 IEAVKK--SLEIEVKNISVRLEEVEAN------AIVGGKRIISKLEAR---IKDMELELD 539
+E K S E+++K +++ + + N AI +R L + I+DM + L+
Sbjct: 1323 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLE 1382
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQK 586
E+++ E ++L K +++ + + E+ ++ + L+ + S K
Sbjct: 1383 EQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNK 1429
Score = 35.5 bits (78), Expect = 0.61
Identities = 113/558 (20%), Positives = 231/558 (41%), Gaps = 65/558 (11%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
Q+ ++ DL KE+ L E+ Q + K + Q EE N Q K
Sbjct: 1205 QEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQ--DMKHLLQLKEEEEETNRQETEKLKE 1262
Query: 202 DFQASRTLVNR----------DYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVR- 250
+ AS DY +L K L A + K + + V + +R++
Sbjct: 1263 ELSASSARTQNLKADLQRKEEDYADL-KEKLTDAKKQIKQVQK-EVSVMRDEDKLLRIKI 1320
Query: 251 ---ETSPTTCVVRINTELPAIDNSYLNQLNELK--ETVKQFD----DLSVY--ILND--- 296
E C ++ + I QLN K E ++Q++ DL+V I+ D
Sbjct: 1321 NELEKKKNQCSQELDMKQRTIQQ-LKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRM 1379
Query: 297 ---SSKQTSIEIEQ-LNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQ 352
+QT +E +Q L A++ E E +L +E+ + K+K T+ + ++ N D+
Sbjct: 1380 TLEEQEQTQVEQDQVLEAKLEEVE-RLATELEKWKEKCNDLETKNNQRSNKEHENNTDVL 1438
Query: 353 KTIKKQSLQLTEIQTHYD-EVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVK 411
+ +L E + Y+ + ++ L+ + A+ E+++ + E+ + +
Sbjct: 1439 GKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQ 1498
Query: 412 RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL-AIVAADY---DEITKELRIADERY 467
+E + + ++L A +E +L A+++++ +EI + RI E
Sbjct: 1499 NEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISET- 1557
Query: 468 QRVQTELKH-TVEHLHEEQERIVKIEAVKKSLEI---EVKNISVRLEEVEANAIVGGKRI 523
+++T++ + + ++ E + S EI ++++ SV L+ E +
Sbjct: 1558 SKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTENDQSTR 1617
Query: 524 ISKLEARIKDMELELDEEKRRH-----AETIKI---LRKKERQLKEVIIQCEEDQKN--- 572
K E I+ L+ ++ +H T+KI ++K +++E +++C E++KN
Sbjct: 1618 FPKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKC-ENKKNATP 1676
Query: 573 -------ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDR-ADV 624
IS ++S K QKV+I SQ S+ V ++ E + D
Sbjct: 1677 RTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEGTLQKFGDF 1736
Query: 625 AESNLSLIRAKHRTFVTT 642
+ + S++++K + + T
Sbjct: 1737 LQHSPSILQSKAKKIIET 1754
>AB209992-1|BAE06074.1| 2319|Homo sapiens DSP variant protein protein.
Length = 2319
Score = 62.1 bits (144), Expect = 6e-09
Identities = 82/369 (22%), Positives = 162/369 (43%), Gaps = 30/369 (8%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
+I++LN ++ +++ E R +K ++ + + + D K ++ + Q L+
Sbjct: 1150 QIKELNEKITRLTYEIEDEKRR-RKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESE 1208
Query: 364 E-IQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQ 422
+ I+ E++R L+V L + G +R ++ + R++ S Q + Q
Sbjct: 1209 KAIKEKEYEIER-LRVLLQEEGTRKREYENELAKASN---------RIQESKNQCTQVVQ 1258
Query: 423 TRVNELTVINVNLSSSKAKI---EQELAIVAADYDEITKELRIADERYQRVQTELKHTVE 479
R + L I V L KA++ E EL + + T+ + + Q++Q +L
Sbjct: 1259 ERESLLVKIKV-LEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKT 1317
Query: 480 HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELD 539
++E I KIE+ ++ E E ++ +E ++A +R KLE ++ + +L+
Sbjct: 1318 QYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLE 1377
Query: 540 EEKRRHAETIKILRKKE-RQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
E+ R+ I LR++ +E +CE L+ D L K + +Y+ QL ++
Sbjct: 1378 TERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLYECQLIDKT 1437
Query: 599 GM-----SQQSVTRV-RRFQRELEAAEDRADVAES---NLSLIRAKHRTFVTTSTVPGSQ 649
+ ++SV V Q L A A + S SL+ AK + ++ P S
Sbjct: 1438 TLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLVEAKRKKLIS----PEST 1493
Query: 650 VYLVQESRA 658
V L++ A
Sbjct: 1494 VMLLEAQAA 1502
Score = 31.9 bits (69), Expect = 7.5
Identities = 53/266 (19%), Positives = 116/266 (43%), Gaps = 21/266 (7%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMY--RGKSAKAIAQTLLEESRRNVQNERMYK 200
K++ EIE+ L ++E E + A R + +K +++E + ++ +
Sbjct: 1212 KEKEYEIERLRVLLQEEGTRKREYENELAKASNRIQESKNQCTQVVQERESLLVKIKVLE 1271
Query: 201 PDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVR 260
D + L D N +K+ L +A K C+ + ++ + + + + +
Sbjct: 1272 QDKARLQRL--EDELNRAKSTL-EAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRK 1328
Query: 261 INTELPAID---NSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET 317
I +E + NS +++ L+ +K+ ++ L DS+++T ++E +R
Sbjct: 1329 IESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREID 1388
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
KL+ ++ Q TE E ++D + L+K K ++QL E Q D +
Sbjct: 1389 KLRQRPYGSHRETQ---TECEWTVDTSKLVFDGLRK--KVTAMQLYECQL-ID------K 1436
Query: 378 VTLDQYGVAQRRIQSLTGEVEE-IRG 402
TLD+ ++ ++ + E++ +RG
Sbjct: 1437 TTLDKLLKGKKSVEEVASEIQPFLRG 1462
>AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparatus
protein 1 variant protein.
Length = 1585
Score = 62.1 bits (144), Expect = 6e-09
Identities = 71/363 (19%), Positives = 154/363 (42%), Gaps = 13/363 (3%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
+ L + ++ +K+ + D ++Q + E+ A + E + LK ++ ++K+ +
Sbjct: 42 SSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK-QLEALEKEKAAK 100
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSL 393
+ L+ L VAN+ Q ++ + + E+ +E+Q ++ + AQ ++ L
Sbjct: 101 LEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL 160
Query: 394 TGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++ + + RV + +Q E+ Q L V +L K + L
Sbjct: 161 ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCI 220
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL-EIEVKNISVRLEEV 512
E+ E R E+++R + EL+ EE+ +EA + L E V E+
Sbjct: 221 SELKAETRSLVEQHKRERKELE-------EERAGRKGLEARLQQLGEAHQAETEVLRREL 273
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKN 572
A A+ S+ E +K++ + + E + + QL + +CE+ ++
Sbjct: 274 -AEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQE 332
Query: 573 ISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLI 632
LQ++ EK + S + Q++ Q+ + + R ++++ E RA +LS +
Sbjct: 333 ---LQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTL 389
Query: 633 RAK 635
+ K
Sbjct: 390 QEK 392
Score = 61.7 bits (143), Expect = 8e-09
Identities = 71/332 (21%), Positives = 144/332 (43%), Gaps = 22/332 (6%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT 363
++EQL++ + + E +LK + + Q +L + + + + +K+
Sbjct: 36 QVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK 95
Query: 364 EIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT 423
E + +Q+QLQV + AQ + E E+ E+ + Q+ E+Q
Sbjct: 96 EKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQA 155
Query: 424 RVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQ----RVQTELKHTVE 479
+V EL + L S + K E VA + D++ ++L+ E + ++ E + +
Sbjct: 156 QVAEL---ELQLRSEQQK-ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAAD 211
Query: 480 HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELD 539
L E+Q I +++A +SL + K LEE A G K + ++L+ + + E +
Sbjct: 212 ALEEQQRCISELKAETRSLVEQHKRERKELEEERA----GRKGLEARLQQLGEAHQAETE 267
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+R AE + E +CE+ K ++ ++ E + Q+ + Y EQ
Sbjct: 268 VLRRELAEAMAAQHTAES-------ECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLM 320
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ + R +EL+ A+++ ES+ L
Sbjct: 321 TLKEECEKAR---QELQEAKEKVAGIESHSEL 349
Score = 49.6 bits (113), Expect = 3e-05
Identities = 52/253 (20%), Positives = 110/253 (43%), Gaps = 21/253 (8%)
Query: 391 QSLTGEVEEIRGNYEQALRVKRS-----VEQQYEESQTRVNELTVINVNLSSSKAKI--- 442
Q L E+++ R Y Q L R+ + + E+Q+ EL V+ +K K+
Sbjct: 947 QFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEE 1006
Query: 443 ----EQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL 498
++E + A +E++K+L +D+ + Q +LK E Q+ +++A L
Sbjct: 1007 RQRFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNEL 1066
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQ 558
+ ++ E + ++ + +A+ K EL E+ R +++ L+K+ ++
Sbjct: 1067 QAQLSQKEQAAEHYKLQM----EKAKTHYDAK-KQQNQELQEQLR----SLEQLQKENKE 1117
Query: 559 LKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
L+ + + + L E+T + ++ R L Q + Q + + +FQ +A
Sbjct: 1118 LRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDAL 1177
Query: 619 EDRADVAESNLSL 631
+ R A+ L L
Sbjct: 1178 KSREPQAKPQLDL 1190
Score = 45.6 bits (103), Expect = 6e-04
Identities = 54/248 (21%), Positives = 120/248 (48%), Gaps = 27/248 (10%)
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVA----ADY 453
+E+ G +QA + + Q ++ + L LSSS + EQ+L VA A
Sbjct: 3 QELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATR 62
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHE-EQERIVKIEAVKKSLEI------------ 500
+ ++L A E + E ++ L E+E+ K+E +++ L++
Sbjct: 63 QDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 122
Query: 501 -----EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
E +S ++EE++A + ++ + +A++ ++EL+L E+++ E ++ ++K
Sbjct: 123 TQAQREKAELSRKVEELQA-CVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEK 181
Query: 556 ERQLKEVIIQCEEDQK-NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRE 614
+ QL+E + +E K L++ + + + +R ++E + ++ V + +R ++E
Sbjct: 182 D-QLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKE 240
Query: 615 LEAAEDRA 622
LE E+RA
Sbjct: 241 LE--EERA 246
Score = 42.7 bits (96), Expect = 0.004
Identities = 84/500 (16%), Positives = 195/500 (39%), Gaps = 24/500 (4%)
Query: 168 QKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVN-RDYTNLSKNVLAKAL 226
++ A G + + L+E S+ Q ER + A T R +L+ A+A
Sbjct: 455 EREAEQMGNELERLRAALME-SQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAE 513
Query: 227 MESKAMNSCDSRVTESIT-ETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQ 285
+E + N+ + + E T + + + +L ++ + + +L EL++TVKQ
Sbjct: 514 LEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQ 573
Query: 286 FDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIK-KKLQIQITELELSLDVA 344
+ + E E + ++E ++E T K + L+ ++++LE
Sbjct: 574 LKE----------QLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQ 623
Query: 345 NKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNY 404
+ L+++++ + E + + +Q QL+ + G +Q + S E+ R
Sbjct: 624 QEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKV 683
Query: 405 EQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIAD 464
+ + + + Q + + +L + + +++ + E+ + +
Sbjct: 684 QDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAES 743
Query: 465 ERYQRVQTELK----HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGG 520
E+ Q+++ L+ T + ER + +SL E + V E +
Sbjct: 744 EKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQA 803
Query: 521 KRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL 580
+R +L +K + E +K + T+++ + L ++ + + + Q +
Sbjct: 804 ER-AEELGQELKAWQ-EKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAA 861
Query: 581 EKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFV 640
EK ++ +Q A G + + R +R EL + E +RA+ ++
Sbjct: 862 EKRHREELEQSKQAA---GGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYA 918
Query: 641 -TTSTVPGSQVYLVQESRAL 659
S + + L +E+R L
Sbjct: 919 EQLSMLKKAHGLLAEENRGL 938
Score = 40.3 bits (90), Expect = 0.021
Identities = 74/381 (19%), Positives = 163/381 (42%), Gaps = 23/381 (6%)
Query: 271 SYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS-EVTRIKKK 329
S LN+ ++ E + +L ++ +S K +E E+L R+++AET S
Sbjct: 719 SILNR--QVLEKEGESKELKRLVMAESEKSQKLE-ERL--RLLQAETASNSARAAERSSA 773
Query: 330 LQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQR---QLQVTLDQYGVA 386
L+ ++ L + + +L++ + Q+ + E+ Q Q + L +
Sbjct: 774 LREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLE 833
Query: 387 QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQE 445
Q+L E+ + +Q + + E+++ E + + + L ++ ++ +
Sbjct: 834 HTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGEL 893
Query: 446 LAI--VAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI-VKIEAVKKSLEIEV 502
+ + A+ + ++LR Y + LK L EE + + ++ LE+E+
Sbjct: 894 IPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVEL 953
Query: 503 KNISVR-LEEVEANAIVGGKRIIS-KLEARIKDMELELDEEKRRHAETIKILRKKER--- 557
+ ++E+ A R+ + EA+ ELE+ K A+ +K+L +++R
Sbjct: 954 DQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAK-VKVLEERQRFQE 1012
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
+ +++ Q EE K ++ + + QK+ + + Q G SQQ R++ EL+A
Sbjct: 1013 ERQKLTAQVEELSKKLADSDQASKVQQQKL----KAVQAQGGESQQEAQRLQAQLNELQA 1068
Query: 618 AEDRADVAESNLSLIRAKHRT 638
+ + A + L K +T
Sbjct: 1069 QLSQKEQAAEHYKLQMEKAKT 1089
Score = 38.7 bits (86), Expect = 0.065
Identities = 40/169 (23%), Positives = 80/169 (47%), Gaps = 17/169 (10%)
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
E ++ Q ++LS L DS + + ++ ++L A V+A+ E + ++LQ Q+ EL
Sbjct: 1013 ERQKLTAQVEELSKK-LADSDQASKVQQQKLKA--VQAQG---GESQQEAQRLQAQLNEL 1066
Query: 338 ELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEV 397
+ L ++ + LQ+ + +THYD ++Q Q +Q R ++ L E
Sbjct: 1067 QAQLS-------QKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQL----RSLEQLQKEN 1115
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
+E+R E+ + + +E++ LT +L + A +Q+L
Sbjct: 1116 KELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL 1164
Score = 37.9 bits (84), Expect = 0.11
Identities = 65/304 (21%), Positives = 126/304 (41%), Gaps = 20/304 (6%)
Query: 304 EIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDL--QKTIKKQSLQ 361
E+ L +V E E + ++ K Q++ L+ + + + N L + + +Q L+
Sbjct: 892 ELIPLRQKVAEQE-RTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLE 950
Query: 362 LTEIQTHYDEVQRQLQVTLD---QYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQ 417
+ Q VQ V D + QR QS E+E + YE A ++V ++
Sbjct: 951 VELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1010
Query: 418 YEESQTRVNELTVINVNLSSS--KAKIEQE-LAIVAADYDEITKELRIADERYQRVQTEL 474
EE Q ++ ++ L+ S +K++Q+ L V A E +E + + +Q +L
Sbjct: 1011 QEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQL 1070
Query: 475 ---KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI 531
+ EH + E+ KK E++ LE+++ K + + EA
Sbjct: 1071 SQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKE----NKEL--RAEAER 1124
Query: 532 KDMELELDEEKRRHAE-TIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIY 590
EL+ K + AE T + L + R L+ + ++ +++ Q + + +
Sbjct: 1125 LGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQA 1184
Query: 591 KRQL 594
K QL
Sbjct: 1185 KPQL 1188
>AL451082-2|CAH72276.1| 1194|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1194
Score = 61.7 bits (143), Expect = 8e-09
Identities = 58/262 (22%), Positives = 113/262 (43%), Gaps = 13/262 (4%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
K+ + +E+L + + +L R+ L +TELE L A + I ++ K
Sbjct: 222 KEDTGRVEELQELLEKQNFELSQARERLVT-LTTTVTELEEDLGTARRDLIKSEELSSKH 280
Query: 359 SLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY 418
L E ++++ ++ +Y AQR S + ++ E L K S+ +Q
Sbjct: 281 QRDLREALAQKEDMEERITTLEKRYLAAQREATS----IHDLNDKLENELANKESLHRQC 336
Query: 419 EESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTV 478
EE + EL + + + L V A+ + L A+ER+ ++ L+
Sbjct: 337 EEKARHLQELLEVAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEEHLRQLE 396
Query: 479 EHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELEL 538
L E+ + + ++ +K E K +S ++ + + + +L+ +K+ L
Sbjct: 397 GQLEEKNQELARVRQREKMNEDHNKRLSDTVDRLLSESN-------ERLQLHLKERMAAL 449
Query: 539 DEEKRRHAETIKILRKKERQLK 560
EEK R +E I+ LR++ QLK
Sbjct: 450 -EEKGRLSEEIEKLRQEVDQLK 470
Score = 37.5 bits (83), Expect = 0.15
Identities = 67/411 (16%), Positives = 175/411 (42%), Gaps = 27/411 (6%)
Query: 223 AKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDN--SYLNQL--NE 278
A A E +N D R E + E++R + + R+ + D +LN E
Sbjct: 22 ADANFEQLMVNMLDER--EKLLESLRESQETLAATQSRLQDAIHERDQLQRHLNSALPQE 79
Query: 279 LKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELE 338
++ +L + + ++ E+ N R++ L+ V+R ++ L++ + + +
Sbjct: 80 FATLTRELSMCREQLLEREEEISELKAERNNTRLLLEH--LECLVSRHERSLRMTVVKRQ 137
Query: 339 LSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE-VQRQLQVTLDQYGVAQRRIQSLTGEV 397
+ +++ K +K L E DE V+ +L+ L++ + ++ +V
Sbjct: 138 AQSPSGVSSEVEVLKALKS----LFEHHKALDEKVRERLRAALERVTTLEEQLAGAHQQV 193
Query: 398 EEIR-------GNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVA 450
++ G E+ V+ ++ ++E RV EL + + ++ + L +
Sbjct: 194 SALQQGAGVRDGAAEEEGTVELGPKRLWKEDTGRVEELQELLEKQNFELSQARERLVTLT 253
Query: 451 ADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLE-IEVKNISVRL 509
E+ ++L A R +++E + + +H + +E + + E +++ + +E + ++ +
Sbjct: 254 TTVTELEEDLGTA--RRDLIKSE-ELSSKHQRDLREALAQKEDMEERITTLEKRYLAAQR 310
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
E + + ++ ++L A + + + +E+ R E +++ +K +Q E
Sbjct: 311 EATSIHDL--NDKLENEL-ANKESLHRQCEEKARHLQELLEVAEQKLQQTMRKAETLPEV 367
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED 620
+ ++ +L K ++ + L + EG ++ + R ++ + ED
Sbjct: 368 EAELAQRIAALTKAEERHGNIEEHLRQLEGQLEEKNQELARVRQREKMNED 418
>AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.
Length = 1583
Score = 61.7 bits (143), Expect = 8e-09
Identities = 77/395 (19%), Positives = 172/395 (43%), Gaps = 37/395 (9%)
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
P++ N L+ + EL+E ++ + K+ + E++N ++ K K E+
Sbjct: 835 PSVKNDPLSSVKELEEKIENLE-----------KECKEKEEKIN-KIKLVAVKAKKELDS 882
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
+K+ Q ELE ++ + ++ I+ + Y++ QL V ++
Sbjct: 883 SRKETQTVKEELESLRSEKDQLSASMRDLIQGAE-SYKNLLLEYEKQSEQLDVEKERANN 941
Query: 386 AQRRIQSLTGEV-------EEIRGNYEQALRVKRSVEQQYEESQTRVNEL----TVINVN 434
+ RI+ LT ++ E I + E L +++ + + ++ E+ +++
Sbjct: 942 FEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKE 1001
Query: 435 LSSSKAKIEQEL---AIVAADYDEITKELRIADERYQRVQTEL---KHTVEHLHEEQERI 488
L + K + EQ++ A + +E+ +L+ ++ Q+ EL K + I
Sbjct: 1002 LEAEKLQKEQKIKEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKDAQQTTLMNMEI 1061
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
E + K L ++ N + ++E++E + K+ L+ I ++ + + + ++ +
Sbjct: 1062 ADYERLMKELNQKLTNKNNKIEDLEQEIKIQ-KQKQETLQEEITSLQSSVQQYEEKNTKI 1120
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISL-LQDSLEKTSQKVSIYKRQLA----EQEGMSQQ 603
++L K +++L + Q E D + L+ LE + Q+V +YK QLA E+ + +
Sbjct: 1121 KQLLVKTKKELADSK-QAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEH 1179
Query: 604 SVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRT 638
T + QR L A + R + +A+ T
Sbjct: 1180 LKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQAT 1214
Score = 53.6 bits (123), Expect = 2e-06
Identities = 74/380 (19%), Positives = 167/380 (43%), Gaps = 28/380 (7%)
Query: 269 DNSYLNQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRI 326
+N+++ Q+ + E VK +D + + S K + L ++ +K E
Sbjct: 221 ENTFVEQV--VNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHE 278
Query: 327 KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT-EIQTHYDEVQ-----RQLQVT- 379
++ L+ +I EL L+ + L+ + + Q ++ H EVQ Q +++
Sbjct: 279 REDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISE 338
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
L++ ++ + LT + EI+G EQ +++ ++ ++ + ++ L S
Sbjct: 339 LNETFLSDSEKEKLT-LMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESA 397
Query: 440 AKIEQELAIV----AADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
KI QE + A+D E+ ++LR A + L TV L E E+++ + +
Sbjct: 398 GKISQEFESMKQQQASDVHELQQKLRTAFTE----KDALLETVNRLQGENEKLLSQQELV 453
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
LE +KN+ E N + +S+ + +K++E +++ + I L+
Sbjct: 454 PELENTIKNLQ------EKNGVY--LLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNS 505
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
++ +CE +++ I L +E+T Q S ++++ E G ++++ + ++L
Sbjct: 506 HEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKL 565
Query: 616 EAAEDRADVAESNLSLIRAK 635
E + V + ++ A+
Sbjct: 566 EKLMVQMKVLSEDKEVLSAE 585
Score = 48.4 bits (110), Expect = 8e-05
Identities = 65/367 (17%), Positives = 167/367 (45%), Gaps = 22/367 (5%)
Query: 283 VKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLD 342
+KQ + SV + D+ K E+EQ + V+ LK+E+ ++ K L+ L+
Sbjct: 1 MKQEVEDSVTKMGDAHK----ELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLE 56
Query: 343 VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRG 402
A T ++L + +K Q+ ++ +E+++ +Q Q+++ + T E +
Sbjct: 57 EAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKK---- 112
Query: 403 NYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS-SKAKIEQELAIVAADYDEITKELR 461
E +++ +E + Q +N L + L + + ++++ + + A E E+
Sbjct: 113 --ETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEIN 170
Query: 462 IADERYQRVQTELKHTVEHLHEEQE-RIVKIEAVKKSLEIEVKNISVRLEE-VEANAIVG 519
+E + + + + + +++ ++ E + + + + + S+ L+E +V
Sbjct: 171 KLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVN 230
Query: 520 GKRIISKLEARIKDMELE--LDEEKRRHAETIKI-LRKKERQLKEVIIQCEEDQKNISLL 576
K + LE +K++E + + +++ + +K+ L + +K+ ED + +
Sbjct: 231 EK--VKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLE-FKIN 287
Query: 577 QDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED--RADVAESNLSLIRA 634
+ L K Q I K + +E G+++Q V + RE+++ ++ + +++E N + +
Sbjct: 288 ELLLAKEEQGCVIEKLK-SELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSD 346
Query: 635 KHRTFVT 641
+ +T
Sbjct: 347 SEKEKLT 353
Score = 44.0 bits (99), Expect = 0.002
Identities = 91/415 (21%), Positives = 176/415 (42%), Gaps = 52/415 (12%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKT--NIDL 351
L+ KQ S ++E ++ + + LK +T+++KKLQ+ + E D NK N +
Sbjct: 596 LSSEKKQLSRDLEVFLSQ--KEDVILKEHITQLEKKLQLMVEEQ----DNLNKLLENEQV 649
Query: 352 QKTIKKQSLQ--LTEIQTHYDEVQRQLQVT--LDQYGVAQRRIQSLTGEVEEIRGNYEQA 407
QK K L L E+ + E + V L G + +I + R E+
Sbjct: 650 QKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRD--EKV 707
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK---ELRIAD 464
L +++ ++ EES + EL + + K + +EL + ++ + + E++ A+
Sbjct: 708 LELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNAN 767
Query: 465 ERYQRVQTELKHTVEH---------LHEEQER--IVKIEAVKKSLEI-EVKNISVRL--- 509
E+ + L VE +H E+E+ I + E +K LE E+++ L
Sbjct: 768 EKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILL 827
Query: 510 -EEVEANAIVGGKRI--ISKLEARIKDMELELDE--EKRRHAETIKILRKKE-----RQL 559
+ + + V + + +LE +I+++E E E EK + + + KKE ++
Sbjct: 828 KDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKET 887
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ---SVTRVRRFQ---- 612
+ V + E + L S+ Q YK L E E S+Q R F+
Sbjct: 888 QTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIE 947
Query: 613 ---RELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
R+L + + + S+ + A+ T + + + Q+ VQ ++A+ + L
Sbjct: 948 DLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKEL 1002
Score = 39.1 bits (87), Expect = 0.049
Identities = 57/329 (17%), Positives = 139/329 (42%), Gaps = 28/329 (8%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
E+ + N E +E + ++ L I+ + +++ + + S+V
Sbjct: 357 EIQGLKEQCENLQQEKQEAILNYESLRE-IMEILQTELGESAGKISQEFESMKQQQASDV 415
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
+++KL+ TE + L+ N+ + +K + +Q L + E++ +Q + V L
Sbjct: 416 HELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQEL-VPELENTIKNLQEKNGVYLLSL 474
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
++ L G++ + EE +N+L + + + K E
Sbjct: 475 SQRDTMLKELEGKINSLT-----------------EEKDDFINKLKNSHEEMDNFHKKCE 517
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+E ++ ++ + ++ E Q+V E L E+ + K+E + +++ +
Sbjct: 518 REERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSE 577
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
+ V EV+ + ++ S+ + +D+E+ L ++ E + IL++ QL++ +
Sbjct: 578 DKEVLSAEVK-SLYEENNKLSSEKKQLSRDLEVFLSQK-----EDV-ILKEHITQLEKKL 630
Query: 564 IQCEEDQKNISLL--QDSLEKTSQKVSIY 590
E+Q N++ L + ++K K +Y
Sbjct: 631 QLMVEEQDNLNKLLENEQVQKLFVKTQLY 659
Score = 37.5 bits (83), Expect = 0.15
Identities = 86/480 (17%), Positives = 183/480 (38%), Gaps = 33/480 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
QKK++Q+ +EL+L +K+ + + + A Y + K + Q L ++ + E+ K
Sbjct: 1033 QKKQLQKTMQELELVKKDAQQTTLMNMEIADYE-RLMKELNQKLTNKNNKIEDLEQEIKI 1091
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
Q TL + T+L +V +K + + + + ++ + ET +
Sbjct: 1092 QKQKQETL-QEEITSLQSSVQQYEEKNTK-IKQLLVKTKKELADS-KQAETDHLILQASL 1148
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS 321
EL A +L E + + + L S++Q + RV T L+
Sbjct: 1149 KGELEASQQQVEVYKIQLAEITSEKHKIHEH-LKTSAEQHQRTLSAYQQRV----TALQE 1203
Query: 322 EVTRIKKKLQIQITELE-LSLDVANKTNIDLQKTIKKQSLQ-LTEIQTHYDEVQRQLQVT 379
E K + +E E + V N K++ + + + + H + + QL++
Sbjct: 1204 ECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIK 1263
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
L +Q +Q E++ ++ ++ L E + E L
Sbjct: 1264 LQD---SQNNLQINVSELQTLQSEHDTLL----------ERHNKMLQETVSKEAELREKL 1310
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL- 498
I+ E ++ +++ + +L +E ++ + V HL EE + V E +++ L
Sbjct: 1311 CSIQSENMMMKSEHTQTVSQLTSQNE---VLRNSFRDQVRHLQEEHRKTV--ETLQQQLS 1365
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME-LELDEEKRRHAETIKILRKKER 557
++E + ++ E + + + + + E R D+ L++ R E ++ +
Sbjct: 1366 KMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESV 1425
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
Q E N + LE K +L ++ + +S + RE EA
Sbjct: 1426 SSASTYTQSLEQLLNSP--ETKLEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEA 1483
>AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.
Length = 1635
Score = 61.7 bits (143), Expect = 8e-09
Identities = 77/395 (19%), Positives = 172/395 (43%), Gaps = 37/395 (9%)
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
P++ N L+ + EL+E ++ + K+ + E++N ++ K K E+
Sbjct: 887 PSVKNDPLSSVKELEEKIENLE-----------KECKEKEEKIN-KIKLVAVKAKKELDS 934
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
+K+ Q ELE ++ + ++ I+ + Y++ QL V ++
Sbjct: 935 SRKETQTVKEELESLRSEKDQLSASMRDLIQGAE-SYKNLLLEYEKQSEQLDVEKERANN 993
Query: 386 AQRRIQSLTGEV-------EEIRGNYEQALRVKRSVEQQYEESQTRVNEL----TVINVN 434
+ RI+ LT ++ E I + E L +++ + + ++ E+ +++
Sbjct: 994 FEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKE 1053
Query: 435 LSSSKAKIEQEL---AIVAADYDEITKELRIADERYQRVQTEL---KHTVEHLHEEQERI 488
L + K + EQ++ A + +E+ +L+ ++ Q+ EL K + I
Sbjct: 1054 LEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEI 1113
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
E + K L ++ N + ++E++E + K+ L+ I ++ + + + ++ +
Sbjct: 1114 ADYERLMKELNQKLTNKNNKIEDLEQEIKIQ-KQKQETLQEEITSLQSSVQQYEEKNTKI 1172
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISL-LQDSLEKTSQKVSIYKRQLA----EQEGMSQQ 603
++L K +++L + Q E D + L+ LE + Q+V +YK QLA E+ + +
Sbjct: 1173 KQLLVKTKKELADSK-QAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEH 1231
Query: 604 SVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRT 638
T + QR L A + R + +A+ T
Sbjct: 1232 LKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQAT 1266
Score = 53.6 bits (123), Expect = 2e-06
Identities = 74/380 (19%), Positives = 167/380 (43%), Gaps = 28/380 (7%)
Query: 269 DNSYLNQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRI 326
+N+++ Q+ + E VK +D + + S K + L ++ +K E
Sbjct: 273 ENTFVEQV--VNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHE 330
Query: 327 KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLT-EIQTHYDEVQ-----RQLQVT- 379
++ L+ +I EL L+ + L+ + + Q ++ H EVQ Q +++
Sbjct: 331 REDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISE 390
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
L++ ++ + LT + EI+G EQ +++ ++ ++ + ++ L S
Sbjct: 391 LNETFLSDSEKEKLT-LMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESA 449
Query: 440 AKIEQELAIV----AADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
KI QE + A+D E+ ++LR A + L TV L E E+++ + +
Sbjct: 450 GKISQEFESMKQQQASDVHELQQKLRTAFTE----KDALLETVNRLQGENEKLLSQQELV 505
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
LE +KN+ E N + +S+ + +K++E +++ + I L+
Sbjct: 506 PELENTIKNLQ------EKNGVY--LLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNS 557
Query: 556 ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
++ +CE +++ I L +E+T Q S ++++ E G ++++ + ++L
Sbjct: 558 HEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKL 617
Query: 616 EAAEDRADVAESNLSLIRAK 635
E + V + ++ A+
Sbjct: 618 EKLMVQMKVLSEDKEVLSAE 637
Score = 49.2 bits (112), Expect = 5e-05
Identities = 66/372 (17%), Positives = 169/372 (45%), Gaps = 24/372 (6%)
Query: 280 KETVKQFDDL--SVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
KE +K ++ SV + D+ K E+EQ + V+ LK+E+ ++ K L
Sbjct: 48 KENIKMKQEVEDSVTKMGDAHK----ELEQSHINYVKEIENLKNELMAVRSKYSEDKANL 103
Query: 338 ELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEV 397
+ L+ A T ++L + +K Q+ ++ +E+++ +Q Q+++ + T E
Sbjct: 104 QKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEK 163
Query: 398 EEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS-SKAKIEQELAIVAADYDEI 456
+ E +++ +E + Q +N L + L + + ++++ + + A E
Sbjct: 164 K------ETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEH 217
Query: 457 TKELRIADERYQRVQTELKHTVEHLHEEQE-RIVKIEAVKKSLEIEVKNISVRLEE-VEA 514
E+ +E + + + + + +++ ++ E + + + + + S+ L+E
Sbjct: 218 EAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFV 277
Query: 515 NAIVGGKRIISKLEARIKDMELE--LDEEKRRHAETIKI-LRKKERQLKEVIIQCEEDQK 571
+V K + LE +K++E + + +++ + +K+ L + +K+ ED +
Sbjct: 278 EQVVNEK--VKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLE 335
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAED--RADVAESNL 629
+ + L K Q I K + +E G+++Q V + RE+++ ++ + +++E N
Sbjct: 336 -FKINELLLAKEEQGCVIEKLK-SELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNE 393
Query: 630 SLIRAKHRTFVT 641
+ + + +T
Sbjct: 394 TFLSDSEKEKLT 405
Score = 44.0 bits (99), Expect = 0.002
Identities = 91/415 (21%), Positives = 176/415 (42%), Gaps = 52/415 (12%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKT--NIDL 351
L+ KQ S ++E ++ + + LK +T+++KKLQ+ + E D NK N +
Sbjct: 648 LSSEKKQLSRDLEVFLSQ--KEDVILKEHITQLEKKLQLMVEEQ----DNLNKLLENEQV 701
Query: 352 QKTIKKQSLQ--LTEIQTHYDEVQRQLQVT--LDQYGVAQRRIQSLTGEVEEIRGNYEQA 407
QK K L L E+ + E + V L G + +I + R E+
Sbjct: 702 QKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRD--EKV 759
Query: 408 LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK---ELRIAD 464
L +++ ++ EES + EL + + K + +EL + ++ + + E++ A+
Sbjct: 760 LELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNAN 819
Query: 465 ERYQRVQTELKHTVEH---------LHEEQER--IVKIEAVKKSLEI-EVKNISVRL--- 509
E+ + L VE +H E+E+ I + E +K LE E+++ L
Sbjct: 820 EKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILL 879
Query: 510 -EEVEANAIVGGKRI--ISKLEARIKDMELELDE--EKRRHAETIKILRKKE-----RQL 559
+ + + V + + +LE +I+++E E E EK + + + KKE ++
Sbjct: 880 KDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKET 939
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ---SVTRVRRFQ---- 612
+ V + E + L S+ Q YK L E E S+Q R F+
Sbjct: 940 QTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIE 999
Query: 613 ---RELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQVYLVQESRALSSERL 664
R+L + + + S+ + A+ T + + + Q+ VQ ++A+ + L
Sbjct: 1000 DLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKEL 1054
Score = 39.1 bits (87), Expect = 0.049
Identities = 57/329 (17%), Positives = 139/329 (42%), Gaps = 28/329 (8%)
Query: 264 ELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV 323
E+ + N E +E + ++ L I+ + +++ + + S+V
Sbjct: 409 EIQGLKEQCENLQQEKQEAILNYESLRE-IMEILQTELGESAGKISQEFESMKQQQASDV 467
Query: 324 TRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQY 383
+++KL+ TE + L+ N+ + +K + +Q L + E++ +Q + V L
Sbjct: 468 HELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQEL-VPELENTIKNLQEKNGVYLLSL 526
Query: 384 GVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIE 443
++ L G++ + EE +N+L + + + K E
Sbjct: 527 SQRDTMLKELEGKINSLT-----------------EEKDDFINKLKNSHEEMDNFHKKCE 569
Query: 444 QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
+E ++ ++ + ++ E Q+V E L E+ + K+E + +++ +
Sbjct: 570 REERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSE 629
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
+ V EV+ + ++ S+ + +D+E+ L ++ E + IL++ QL++ +
Sbjct: 630 DKEVLSAEVK-SLYEENNKLSSEKKQLSRDLEVFLSQK-----EDV-ILKEHITQLEKKL 682
Query: 564 IQCEEDQKNISLL--QDSLEKTSQKVSIY 590
E+Q N++ L + ++K K +Y
Sbjct: 683 QLMVEEQDNLNKLLENEQVQKLFVKTQLY 711
Score = 36.3 bits (80), Expect = 0.35
Identities = 85/480 (17%), Positives = 183/480 (38%), Gaps = 33/480 (6%)
Query: 142 QKKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+KK++Q+ +EL+L +K+ + + + A Y + K + Q L ++ + E+ K
Sbjct: 1085 EKKQLQKTMQELELVKKDAQQTTLMNMEIADYE-RLMKELNQKLTNKNNKIEDLEQEIKI 1143
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
Q TL + T+L +V +K + + + + ++ + ET +
Sbjct: 1144 QKQKQETL-QEEITSLQSSVQQYEEKNTK-IKQLLVKTKKELADS-KQAETDHLILQASL 1200
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKS 321
EL A +L E + + + L S++Q + RV T L+
Sbjct: 1201 KGELEASQQQVEVYKIQLAEITSEKHKIHEH-LKTSAEQHQRTLSAYQQRV----TALQE 1255
Query: 322 EVTRIKKKLQIQITELE-LSLDVANKTNIDLQKTIKKQSLQ-LTEIQTHYDEVQRQLQVT 379
E K + +E E + V N K++ + + + + H + + QL++
Sbjct: 1256 ECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIK 1315
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
L +Q +Q E++ ++ ++ L E + E L
Sbjct: 1316 LQD---SQNNLQINVSELQTLQSEHDTLL----------ERHNKMLQETVSKEAELREKL 1362
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSL- 498
I+ E ++ +++ + +L +E ++ + V HL EE + V E +++ L
Sbjct: 1363 CSIQSENMMMKSEHTQTVSQLTSQNE---VLRNSFRDQVRHLQEEHRKTV--ETLQQQLS 1417
Query: 499 EIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME-LELDEEKRRHAETIKILRKKER 557
++E + ++ E + + + + + E R D+ L++ R E ++ +
Sbjct: 1418 KMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESV 1477
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
Q E N + LE K +L ++ + +S + RE EA
Sbjct: 1478 SSASTYTQSLEQLLNSP--ETKLEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEA 1535
>BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for
IMAGE:40131779) protein.
Length = 416
Score = 61.3 bits (142), Expect = 1e-08
Identities = 72/327 (22%), Positives = 152/327 (46%), Gaps = 18/327 (5%)
Query: 318 KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQ 377
+L+++V I+ L Q TEL+++L + L+ + +L + E+++ L
Sbjct: 82 ELEAQVHTIRI-LTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALS 140
Query: 378 VTLDQYGVAQRRIQSLTGEVE----EIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
Q A R I+ LT E + E+ N +K + E+ Q +E + I +
Sbjct: 141 AVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQL 200
Query: 434 NLSSSKAKIEQELAIVA----ADYDEITKELRIADERYQRVQTELKHTVEHLHEEQE-RI 488
N+ K K+E+ ++ A+ D + KEL+ + Q Q E L+++QE ++
Sbjct: 201 NVKELKRKLERAKLLLPQQLQAEADHLGKELQSVSAKLQ-AQVEENELWNRLNQQQEEKM 259
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK--RRHA 546
+ E + E +++ ++ E E I + ++ + E ++ + E ++ E++ RR
Sbjct: 260 WRQEEKIQEWEEKIQEQEEKIREQEEK-IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE 318
Query: 547 ETIKILRKKERQLKEVIIQCEE----DQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
E I+ +K R+ KE I + EE ++ I ++ +++ +K+ + ++ EQE Q
Sbjct: 319 EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 378
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNL 629
+ ++RR + ++ E R E +
Sbjct: 379 EQEEKMRRQEEKMWEQEVRLRQQEEKM 405
Score = 52.8 bits (121), Expect = 4e-06
Identities = 60/331 (18%), Positives = 153/331 (46%), Gaps = 18/331 (5%)
Query: 289 LSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTN 348
+++Y + KQ E L +R+ ++ K E+ + + Q + + ++ K
Sbjct: 102 MALYYSQHAVKQLEGEARDLISRLHDS-WKFAGELEQALSAVATQKKKADRYIEELTKER 160
Query: 349 IDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQAL 408
L + + ++ E++ ++Q +LQ+ + Q ++ L ++E
Sbjct: 161 DALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE---------- 210
Query: 409 RVKRSVEQQYE-ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERY 467
R K + QQ + E+ EL ++ L +A++E+ + + K R +E+
Sbjct: 211 RAKLLLPQQLQAEADHLGKELQSVSAKL---QAQVEENELWNRLNQQQEEKMWR-QEEKI 266
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
Q + +++ E + E++E+I + E + + E ++ +++E E K I +
Sbjct: 267 QEWEEKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK--IREQ 324
Query: 528 EARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
E +I++ + ++ E++ + E + +R++E ++E + E ++ + ++ +++ +K+
Sbjct: 325 EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 384
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAA 618
+ ++ EQE +Q +++ Q LEAA
Sbjct: 385 RRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 415
>BC014109-1|AAH14109.1| 670|Homo sapiens leucine rich repeat
containing 45 protein.
Length = 670
Score = 61.3 bits (142), Expect = 1e-08
Identities = 89/393 (22%), Positives = 177/393 (45%), Gaps = 40/393 (10%)
Query: 261 INTELPAIDNSYLNQLNELKETV-KQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ E+ + Q +L ET+ KQ ++++ SS+ ++ + QL EA +
Sbjct: 244 LSKEVQHLREEKSKQFLDLMETIDKQREEMA-----KSSRASAARVGQLQ----EALNER 294
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
S + +K KLQ+ L LS A +L T +++ L L++ Q E++ + Q
Sbjct: 295 HSIINALKAKLQMTEAALALSEQKAQDLG-ELLATAEQEQLSLSQRQAK--ELKLEQQEA 351
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSK 439
++ R + + + ++ ++ R R QQ + QTR E+T ++ L
Sbjct: 352 AERESKLLRDLSAANEKNLLLQNQVDELERKFRC--QQEQLFQTR-QEMTSMSAELKMRA 408
Query: 440 AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE----QERIVKIEAVK 495
+ E+ L D ++ + D R++ E++H HL E QER+ ++EA +
Sbjct: 409 IQAEERL-----DMEKRRCRQSLEDSESLRIK-EVEHMTRHLEESEKAMQERVQRLEAAR 462
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME--LELDEEKRRHAETIKILR 553
SLE E+ V+ + + I +K +AR+++ + L+++ R A+ +
Sbjct: 463 LSLEEELSR--VKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQARDEAQ 520
Query: 554 KKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR---- 609
Q K+V+ + + + L + L + +++ + L +QE +++ S RV
Sbjct: 521 GACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQ-QELSLKDQERVAEVSRVRVELQEQ 579
Query: 610 --RFQREL---EAAEDRADVAESNLSLIRAKHR 637
R Q EL EA ++A E L ++ + HR
Sbjct: 580 NGRLQAELAAQEALREKAAALERQLKVMASDHR 612
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 61.3 bits (142), Expect = 1e-08
Identities = 79/362 (21%), Positives = 166/362 (45%), Gaps = 32/362 (8%)
Query: 236 DSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILN 295
D +V S E ++ +ET + +NT++ + L ++L K +L I+
Sbjct: 313 DKKVENSNKEEIQEKET----IIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 368
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ + ++++E N++ + E + E+ K+L + EL+ ++ D+ + +
Sbjct: 369 KNQEIKNMKLELTNSK--QKERQSSEEI----KQLMGTVEELQKRNHKDSQFETDIVQRM 422
Query: 356 KKQSLQ-LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++++ + L +++ DE+ Q V + Q + Q Q + +G E ALR ++
Sbjct: 423 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRH-KGEMENALRSYSNI 481
Query: 415 ---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD-------YDEITKELRIAD 464
E Q + +NEL + + +S K K+++EL ++ + +++ +EL +
Sbjct: 482 TVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSR 541
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
E+ QR + + L+E + + +E +K EI + S + E++ A V +I
Sbjct: 542 EQIQRARQTIAEQESKLNEAHKSLSTVEDLK--AEIVSASESRKELELKHEAEVTNYKI- 598
Query: 525 SKLEARIKDMELELD---EEKRRHAETIK--ILRKKERQLKEVIIQCE-EDQKNISLLQD 578
KLE K+ LD E + E ++ +L E +L ++ E E + NI L+D
Sbjct: 599 -KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKD 657
Query: 579 SL 580
+L
Sbjct: 658 NL 659
Score = 51.6 bits (118), Expect = 9e-06
Identities = 67/366 (18%), Positives = 163/366 (44%), Gaps = 28/366 (7%)
Query: 258 VVRINTELPAIDNSY----LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVV 313
+ +N EL + +Y L QL E + +KQ D + Q + ++Q AR
Sbjct: 171 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIIT--------QLTANLQQ--ARRE 220
Query: 314 EAETKLKS-EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
+ ET + E+T +KLQIQ +L+ S + N T+ + + Q I TH ++
Sbjct: 221 KDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQ---ILTHQQQL 277
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIR-GNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+ Q + D + ++ E+I+ EQ +V+ S +++ +E +T + EL
Sbjct: 278 EEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTK 337
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI 491
+ +++ +L E+ +++ ++ + ++ EL ++ + + E I ++
Sbjct: 338 IIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQL 397
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK- 550
+ E++ +N + + E + + +R+ + + +++ + ELDE + +K
Sbjct: 398 MGTVE--ELQKRN--HKDSQFETDIV---QRMEQETQRKLEQLRAELDEMYGQQIVQMKQ 450
Query: 551 -ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
++R+ Q++E+ + + + +N ++ ++ + + E Q + ++
Sbjct: 451 ELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE 510
Query: 610 RFQREL 615
+ + EL
Sbjct: 511 KLKEEL 516
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/373 (16%), Positives = 160/373 (42%), Gaps = 19/373 (5%)
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+++ TEL ++ + N+L+E Q + + IL D K+T ++ +++ V + E
Sbjct: 748 LQLKTEL--LEKQMKEKENDLQEKFAQLEAENS-ILKDE-KKTLEDMLKIHTPVSQEERL 803
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ + + K K + E+E+ ++ N DL++ + + ++ + + + ++ +V
Sbjct: 804 IFLDSIKSKSKDSVWEKEIEILIE----ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 859
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVN--L 435
+ + + ++E+ + +Q L K ++ EE R+N TV +
Sbjct: 860 NYQELQEEYACLLKVKDDLEDSKN--KQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 917
Query: 436 SSSKAKIEQELA---IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
K + + L +V D E+ ++L + + L E L ++ I +
Sbjct: 918 DEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLN 977
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE-TIKI 551
KSL+ E + +S+R E+E + + ++ + + R AE ++
Sbjct: 978 EEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSK 1037
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
+ K + +++++ + +N+++ ++S K Q + + + ++ + + +
Sbjct: 1038 VNKSFGEESKIMVEDKVSFENMTVGEES--KQEQLILDHLPSVTKESSLRATQPSENDKL 1095
Query: 612 QRELEAAEDRADV 624
Q+EL + D+
Sbjct: 1096 QKELNVLKSEQDL 1108
>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
Length = 3908
Score = 61.3 bits (142), Expect = 1e-08
Identities = 79/362 (21%), Positives = 166/362 (45%), Gaps = 32/362 (8%)
Query: 236 DSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILN 295
D +V S E ++ +ET + +NT++ + L ++L K +L I+
Sbjct: 313 DKKVENSNKEEIQEKET----IIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 368
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ + ++++E N++ + E + E+ K+L + EL+ ++ D+ + +
Sbjct: 369 KNQEIKNMKLELTNSK--QKERQSSEEI----KQLMGTVEELQKRNHKDSQFETDIVQRM 422
Query: 356 KKQSLQ-LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++++ + L +++ DE+ Q V + Q + Q Q + +G E ALR ++
Sbjct: 423 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRH-KGEMENALRSYSNI 481
Query: 415 ---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD-------YDEITKELRIAD 464
E Q + +NEL + + +S K K+++EL ++ + +++ +EL +
Sbjct: 482 TVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSR 541
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
E+ QR + + L+E + + +E +K EI + S + E++ A V +I
Sbjct: 542 EQIQRARQTIAEQESKLNEAHKSLSTVEDLK--AEIVSASESRKELELKHEAEVTNYKI- 598
Query: 525 SKLEARIKDMELELD---EEKRRHAETIK--ILRKKERQLKEVIIQCE-EDQKNISLLQD 578
KLE K+ LD E + E ++ +L E +L ++ E E + NI L+D
Sbjct: 599 -KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKD 657
Query: 579 SL 580
+L
Sbjct: 658 NL 659
Score = 55.2 bits (127), Expect = 7e-07
Identities = 107/512 (20%), Positives = 219/512 (42%), Gaps = 41/512 (8%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
R+QE+E E ++E L S RQK AM A + Q LL+E+ + + E++ + Q
Sbjct: 1959 RLQELEAEQQQIQEERELLS--RQKEAMKA--EAGPVEQQLLQETEK-LMKEKL-EVQCQ 2012
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCV----VR 260
A + RD +L K V A + + ++ E TE + +R+ + +R
Sbjct: 2013 AEKV---RD--DLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMR 2067
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYI-LNDSSKQTSIEIEQLNARVVEAETKL 319
+ AID + + + +E K L V S+ + E+EQL A ++ +T
Sbjct: 2068 KFLDEQAIDREHERDVFQ-QEIQKLEQQLKVVPRFQPISEHQTREVEQL-ANHLKEKTDK 2125
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKT--IKKQSLQLTEIQTHYDEVQR--- 374
SE+ K++LQ I E ++ +L++ + + Q E + H+ V+
Sbjct: 2126 CSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPE 2185
Query: 375 -----QLQVTLDQYGVAQRRIQSLTGEVEEIR----GNYEQALRVKRSVEQQYEESQTRV 425
QLQ D ++ I +L ++E+ R E+ ++ +E Q +ES TR+
Sbjct: 2186 LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRL 2245
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
EL N K+ LAI +D T++ + ++ ++ E + ++ L+E+
Sbjct: 2246 QELEQENKLFKDDMEKL--GLAIKESDAMS-TQDQHVLFGKFAQIIQEKEVEIDQLNEQV 2302
Query: 486 ERI-VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISK-LEARIKDMELELDEEKR 543
++ +++ + IE KN +R E + ++ + + + E I+ + +++ ++
Sbjct: 2303 TKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ 2362
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNI----SLLQDSLEKTSQKVSIYKRQLAEQEG 599
A + L E + + L+ +E +++++ K L E
Sbjct: 2363 ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNF 2422
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
Q + +RE E+ E + E+++++
Sbjct: 2423 KMNQLTQELFSLKRERESVEKIQSIPENSVNV 2454
Score = 51.6 bits (118), Expect = 9e-06
Identities = 67/366 (18%), Positives = 163/366 (44%), Gaps = 28/366 (7%)
Query: 258 VVRINTELPAIDNSY----LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVV 313
+ +N EL + +Y L QL E + +KQ D + Q + ++Q AR
Sbjct: 171 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIIT--------QLTANLQQ--ARRE 220
Query: 314 EAETKLKS-EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
+ ET + E+T +KLQIQ +L+ S + N T+ + + Q I TH ++
Sbjct: 221 KDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQ---ILTHQQQL 277
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIR-GNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+ Q + D + ++ E+I+ EQ +V+ S +++ +E +T + EL
Sbjct: 278 EEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTK 337
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI 491
+ +++ +L E+ +++ ++ + ++ EL ++ + + E I ++
Sbjct: 338 IIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQL 397
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK- 550
+ E++ +N + + E + + +R+ + + +++ + ELDE + +K
Sbjct: 398 MGTVE--ELQKRN--HKDSQFETDIV---QRMEQETQRKLEQLRAELDEMYGQQIVQMKQ 450
Query: 551 -ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
++R+ Q++E+ + + + +N ++ ++ + + E Q + ++
Sbjct: 451 ELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE 510
Query: 610 RFQREL 615
+ + EL
Sbjct: 511 KLKEEL 516
Score = 42.3 bits (95), Expect = 0.005
Identities = 92/431 (21%), Positives = 190/431 (44%), Gaps = 54/431 (12%)
Query: 157 EKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTN 216
E EV S+ + + +RG+ A+ Q LEE R+V ++ + A T N
Sbjct: 3007 EAEVYDSSQSHESFSDWRGELLLALQQVFLEE--RSVL-LAAFRTELTALGTTDAVGLLN 3063
Query: 217 -LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQ 275
L + + + + AM S+ ++ + + E + S +
Sbjct: 3064 CLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPS--QE 3121
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEI-EQLNA-RVVEAETKLKSEVTRIKKKLQI- 332
L E KQ L + + S K + E+ EQL++ ++V AE LKSE+ + K +L+
Sbjct: 3122 LLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAE--LKSELAQTKLELETT 3179
Query: 333 ------QITELE-LSLDVANKT----------------NIDLQKTIKKQSLQLTEIQTHY 369
+ ELE L+V +KT + +LQ ++K+ +L +
Sbjct: 3180 LKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERD 3239
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV-EQQYEESQTRVNEL 428
E L+ +L+ ++ L + +++ +Q + +R + + Q E Q R EL
Sbjct: 3240 KEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLEL 3299
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR---VQTE--LKHTVEHLHE 483
V+ L S K +I +E++ E+ +L+ +D Q + +E LK + L E
Sbjct: 3300 QVL---LESEKVRI-REMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEE 3355
Query: 484 EQERIV---------KIEAVKKSLEIEV-KNISVRLEEVEANAIVGGKRIISKLEARIKD 533
+ RIV K+++++ ++E + + + + E A G++ + +L+++++D
Sbjct: 3356 KHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVED 3415
Query: 534 MELELDEEKRR 544
++ +L+E++++
Sbjct: 3416 LQRQLEEKRQQ 3426
Score = 36.7 bits (81), Expect = 0.26
Identities = 61/364 (16%), Positives = 156/364 (42%), Gaps = 19/364 (5%)
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+++ TEL ++ + N+L+E Q + + IL D K+T ++ +++ V + E
Sbjct: 748 LQLKTEL--LEKQMKEKENDLQEKFAQLEAENS-ILKDE-KKTLEDMLKIHTPVSQEERL 803
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ + + K K + E+E+ ++ N DL++ + + ++ + + + ++ +V
Sbjct: 804 IFLDSIKSKSKDSVWEKEIEILIE----ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 859
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVN--L 435
+ + + ++E+ + +Q L K ++ EE R+N TV +
Sbjct: 860 NYQELQEEYACLLKVKDDLEDSKN--KQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 917
Query: 436 SSSKAKIEQELA---IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
K + + L +V D E+ ++L + + L E L + I +
Sbjct: 918 DEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKPKPGEISFLN 977
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE-TIKI 551
KSL+ E + +S+R E+E + + ++ + + R AE ++
Sbjct: 978 EEVKSLKPEKEPVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSK 1037
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
+ K + +++++ + +N+++ ++S K Q + + + ++ + + +
Sbjct: 1038 VNKSFGEESKIMVEDKVSFENMTVGEES--KQEQLILDHLPSVTKESSLRATQPSENDKL 1095
Query: 612 QREL 615
Q+EL
Sbjct: 1096 QKEL 1099
Score = 35.5 bits (78), Expect = 0.61
Identities = 52/276 (18%), Positives = 117/276 (42%), Gaps = 30/276 (10%)
Query: 331 QIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI 390
Q Q+ E+++ L +LQ+ + + + + E+++ + + +L+ TL + +
Sbjct: 3131 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLK---AQHKHL 3187
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVA 450
+ L E++ ++ + ++ + ++S+ L L S+ + ++EL
Sbjct: 3188 KELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEEL---- 3243
Query: 451 ADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLE 510
+++ L +R ++ L+ + L+E Q+ KIE+ + + ++ R
Sbjct: 3244 ---EDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQ---KIESQRMLYDAQLSEEQGRNL 3297
Query: 511 EVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE--------TIKILRKKERQLKEV 562
E++ ++ + RI++M LD E+ HA+ + E LKE+
Sbjct: 3298 ELQV--------LLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKEL 3349
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
Q EE I L + EK S+ RQ E++
Sbjct: 3350 QKQLEEKHSRIVELLNETEKYKLD-SLQTRQQMEKD 3384
Score = 34.7 bits (76), Expect = 1.1
Identities = 66/325 (20%), Positives = 136/325 (41%), Gaps = 25/325 (7%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS 359
Q +E Q A+ + + SE R + Q+ E EL D++ T++
Sbjct: 2559 QIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDIS-------ALTLRISE 2611
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI-RGNYE-QALRVKRSVEQQ 417
L+ ++ H + + QV + + V ++ + L E++++ GN + Q + K+ Q
Sbjct: 2612 LESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLL--ELQKLLEGNEKKQREKEKKRSPQD 2669
Query: 418 YEESQTRV-----NELTVINVNLSSSKAK---IEQELAIVAADYDEITKELRIADERYQR 469
E +T NE + L + +A+ + ELA +++ +EL + +
Sbjct: 2670 VEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTS 2729
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEA 529
+Q +L +HL E +E K+ ++K E EV+ S + E I K I S+ +
Sbjct: 2730 LQKDLSQVRDHLAEAKE---KLSILEKEDETEVQE-SKKACMFEPLPIKLSKSIASQTDG 2785
Query: 530 RIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
+K + I+I + E +EV + + I +Q+ ++ + +
Sbjct: 2786 TLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQEL--HAAEILDM 2843
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRE 614
R ++E E + ++ V+ + E
Sbjct: 2844 ESRHISETETLKREHYVAVQLLKEE 2868
Score = 34.3 bits (75), Expect = 1.4
Identities = 86/458 (18%), Positives = 187/458 (40%), Gaps = 39/458 (8%)
Query: 146 MQEIEKELDLYEKEVNLGSE-LRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++++++EL ++ ++ + L ++A + + IA+ L E + NE M F
Sbjct: 2357 IEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEM---TFM 2413
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ V ++ TN N L + L K R ES+ + + E S + ++ +
Sbjct: 2414 KN---VLKE-TNFKMNQLTQELFSLK-------RERESVEKIQSIPENSVNVAIDHLSKD 2462
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
P ++ + E F ++ K + I +E ++ + E+T
Sbjct: 2463 KPELEVVLTEDALKSLENQTYFKSFE-----ENGKGSIINLETRLLQLESTVSAKDLELT 2517
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
+ K+++ + + ++ K ++LQK ++++ Q + VQ + D
Sbjct: 2518 QCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQT 2577
Query: 385 VA----QRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRV----NELTVINVN- 434
++ + IQ+L E+ G+ AL ++ S +E Q E T + ++ + N
Sbjct: 2578 ISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNV 2637
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIA--DERYQRVQTELKHTVEHLHEEQERIVKIE 492
L K +E + + + + KE + + D + TEL H+ E E + +
Sbjct: 2638 LEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNE-LEALR 2696
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
A + + E+ + + E+++ +V + S L+ + + L E K E + IL
Sbjct: 2697 AESVATKAELASYKEKAEKLQEELLVKETNMTS-LQKDLSQVRDHLAEAK----EKLSIL 2751
Query: 553 RKK-ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
K+ E +++E C + I L + +T + I
Sbjct: 2752 EKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKI 2789
>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
Length = 3911
Score = 61.3 bits (142), Expect = 1e-08
Identities = 79/362 (21%), Positives = 166/362 (45%), Gaps = 32/362 (8%)
Query: 236 DSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILN 295
D +V S E ++ +ET + +NT++ + L ++L K +L I+
Sbjct: 325 DKKVENSNKEEIQEKET----IIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 380
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ + ++++E N++ + E + E+ K+L + EL+ ++ D+ + +
Sbjct: 381 KNQEIKNMKLELTNSK--QKERQSSEEI----KQLMGTVEELQKRNHKDSQFETDIVQRM 434
Query: 356 KKQSLQ-LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++++ + L +++ DE+ Q V + Q + Q Q + +G E ALR ++
Sbjct: 435 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRH-KGEMENALRSYSNI 493
Query: 415 ---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD-------YDEITKELRIAD 464
E Q + +NEL + + +S K K+++EL ++ + +++ +EL +
Sbjct: 494 TVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSR 553
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
E+ QR + + L+E + + +E +K EI + S + E++ A V +I
Sbjct: 554 EQIQRARQTIAEQESKLNEAHKSLSTVEDLK--AEIVSASESRKELELKHEAEVTNYKI- 610
Query: 525 SKLEARIKDMELELD---EEKRRHAETIK--ILRKKERQLKEVIIQCE-EDQKNISLLQD 578
KLE K+ LD E + E ++ +L E +L ++ E E + NI L+D
Sbjct: 611 -KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKD 669
Query: 579 SL 580
+L
Sbjct: 670 NL 671
Score = 55.2 bits (127), Expect = 7e-07
Identities = 107/512 (20%), Positives = 219/512 (42%), Gaps = 41/512 (8%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
R+QE+E E ++E L S RQK AM A + Q LL+E+ + + E++ + Q
Sbjct: 1970 RLQELEAEQQQIQEERELLS--RQKEAMKA--EAGPVEQQLLQETEK-LMKEKL-EVQCQ 2023
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCV----VR 260
A + RD +L K V A + + ++ E TE + +R+ + +R
Sbjct: 2024 AEKV---RD--DLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMR 2078
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYI-LNDSSKQTSIEIEQLNARVVEAETKL 319
+ AID + + + +E K L V S+ + E+EQL A ++ +T
Sbjct: 2079 KFLDEQAIDREHERDVFQ-QEIQKLEQQLKVVPRFQPISEHQTREVEQL-ANHLKEKTDK 2136
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKT--IKKQSLQLTEIQTHYDEVQR--- 374
SE+ K++LQ I E ++ +L++ + + Q E + H+ V+
Sbjct: 2137 CSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPE 2196
Query: 375 -----QLQVTLDQYGVAQRRIQSLTGEVEEIR----GNYEQALRVKRSVEQQYEESQTRV 425
QLQ D ++ I +L ++E+ R E+ ++ +E Q +ES TR+
Sbjct: 2197 LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRL 2256
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
EL N K+ LAI +D T++ + ++ ++ E + ++ L+E+
Sbjct: 2257 QELEQENKLFKDDMEKL--GLAIKESDAMS-TQDQHVLFGKFAQIIQEKEVEIDQLNEQV 2313
Query: 486 ERI-VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISK-LEARIKDMELELDEEKR 543
++ +++ + IE KN +R E + ++ + + + E I+ + +++ ++
Sbjct: 2314 TKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ 2373
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNI----SLLQDSLEKTSQKVSIYKRQLAEQEG 599
A + L E + + L+ +E +++++ K L E
Sbjct: 2374 ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNF 2433
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
Q + +RE E+ E + E+++++
Sbjct: 2434 KMNQLTQELFSLKRERESVEKIQSIPENSVNV 2465
Score = 51.6 bits (118), Expect = 9e-06
Identities = 67/366 (18%), Positives = 163/366 (44%), Gaps = 28/366 (7%)
Query: 258 VVRINTELPAIDNSY----LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVV 313
+ +N EL + +Y L QL E + +KQ D + Q + ++Q AR
Sbjct: 183 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIIT--------QLTANLQQ--ARRE 232
Query: 314 EAETKLKS-EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
+ ET + E+T +KLQIQ +L+ S + N T+ + + Q I TH ++
Sbjct: 233 KDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQ---ILTHQQQL 289
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIR-GNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+ Q + D + ++ E+I+ EQ +V+ S +++ +E +T + EL
Sbjct: 290 EEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTK 349
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI 491
+ +++ +L E+ +++ ++ + ++ EL ++ + + E I ++
Sbjct: 350 IIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQL 409
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK- 550
+ E++ +N + + E + + +R+ + + +++ + ELDE + +K
Sbjct: 410 MGTVE--ELQKRN--HKDSQFETDIV---QRMEQETQRKLEQLRAELDEMYGQQIVQMKQ 462
Query: 551 -ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
++R+ Q++E+ + + + +N ++ ++ + + E Q + ++
Sbjct: 463 ELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE 522
Query: 610 RFQREL 615
+ + EL
Sbjct: 523 KLKEEL 528
Score = 42.3 bits (95), Expect = 0.005
Identities = 92/431 (21%), Positives = 190/431 (44%), Gaps = 54/431 (12%)
Query: 157 EKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTN 216
E EV S+ + + +RG+ A+ Q LEE R+V ++ + A T N
Sbjct: 3010 EAEVYDSSQSHESFSDWRGELLLALQQVFLEE--RSVL-LAAFRTELTALGTTDAVGLLN 3066
Query: 217 -LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQ 275
L + + + + AM S+ ++ + + E + S +
Sbjct: 3067 CLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPS--QE 3124
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEI-EQLNA-RVVEAETKLKSEVTRIKKKLQI- 332
L E KQ L + + S K + E+ EQL++ ++V AE LKSE+ + K +L+
Sbjct: 3125 LLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAE--LKSELAQTKLELETT 3182
Query: 333 ------QITELE-LSLDVANKT----------------NIDLQKTIKKQSLQLTEIQTHY 369
+ ELE L+V +KT + +LQ ++K+ +L +
Sbjct: 3183 LKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERD 3242
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV-EQQYEESQTRVNEL 428
E L+ +L+ ++ L + +++ +Q + +R + + Q E Q R EL
Sbjct: 3243 KEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLEL 3302
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR---VQTE--LKHTVEHLHE 483
V+ L S K +I +E++ E+ +L+ +D Q + +E LK + L E
Sbjct: 3303 QVL---LESEKVRI-REMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEE 3358
Query: 484 EQERIV---------KIEAVKKSLEIEV-KNISVRLEEVEANAIVGGKRIISKLEARIKD 533
+ RIV K+++++ ++E + + + + E A G++ + +L+++++D
Sbjct: 3359 KHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVED 3418
Query: 534 MELELDEEKRR 544
++ +L+E++++
Sbjct: 3419 LQRQLEEKRQQ 3429
Score = 39.1 bits (87), Expect = 0.049
Identities = 61/364 (16%), Positives = 157/364 (43%), Gaps = 19/364 (5%)
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+++ TEL ++ + N+L+E Q + + IL D K+T ++ +++ V + E
Sbjct: 760 LQLKTEL--LEKQMKEKENDLQEKFAQLEAENS-ILKDE-KKTLEDMLKIHTPVSQEERL 815
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ + + K K + E+E+ ++ N DL++ + + ++ + + + ++ +V
Sbjct: 816 IFLDSIKSKSKDSVWEKEIEILIE----ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 871
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVN--L 435
+ + + ++E+ + +Q L K ++ EE R+N TV +
Sbjct: 872 NYQELQEEYACLLKVKDDLEDSKN--KQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 929
Query: 436 SSSKAKIEQELA---IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
K + + L +V D E+ ++L + + L E L ++ I +
Sbjct: 930 DEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLN 989
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE-TIKI 551
KSL+ E + +S+R E+E + + ++ + + R AE ++
Sbjct: 990 EEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSK 1049
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
+ K + +++++ + +N+++ ++S K Q + + + ++ + + +
Sbjct: 1050 VNKSFGEESKIMVEDKVSFENMTVGEES--KQEQLILDHLPSVTKESSLRATQPSENDKL 1107
Query: 612 QREL 615
Q+EL
Sbjct: 1108 QKEL 1111
Score = 35.5 bits (78), Expect = 0.61
Identities = 52/276 (18%), Positives = 117/276 (42%), Gaps = 30/276 (10%)
Query: 331 QIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI 390
Q Q+ E+++ L +LQ+ + + + + E+++ + + +L+ TL + +
Sbjct: 3134 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLK---AQHKHL 3190
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVA 450
+ L E++ ++ + ++ + ++S+ L L S+ + ++EL
Sbjct: 3191 KELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEEL---- 3246
Query: 451 ADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLE 510
+++ L +R ++ L+ + L+E Q+ KIE+ + + ++ R
Sbjct: 3247 ---EDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQ---KIESQRMLYDAQLSEEQGRNL 3300
Query: 511 EVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE--------TIKILRKKERQLKEV 562
E++ ++ + RI++M LD E+ HA+ + E LKE+
Sbjct: 3301 ELQV--------LLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKEL 3352
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
Q EE I L + EK S+ RQ E++
Sbjct: 3353 QKQLEEKHSRIVELLNETEKYKLD-SLQTRQQMEKD 3387
Score = 34.7 bits (76), Expect = 1.1
Identities = 66/325 (20%), Positives = 136/325 (41%), Gaps = 25/325 (7%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS 359
Q +E Q A+ + + SE R + Q+ E EL D++ T++
Sbjct: 2570 QIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDIS-------ALTLRISE 2622
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI-RGNYE-QALRVKRSVEQQ 417
L+ ++ H + + QV + + V ++ + L E++++ GN + Q + K+ Q
Sbjct: 2623 LESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLL--ELQKLLEGNEKKQREKEKKRSPQD 2680
Query: 418 YEESQTRV-----NELTVINVNLSSSKAK---IEQELAIVAADYDEITKELRIADERYQR 469
E +T NE + L + +A+ + ELA +++ +EL + +
Sbjct: 2681 VEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTS 2740
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEA 529
+Q +L +HL E +E K+ ++K E EV+ S + E I K I S+ +
Sbjct: 2741 LQKDLSQVRDHLAEAKE---KLSILEKEDETEVQE-SKKACMFEPLPIKLSKSIASQTDG 2796
Query: 530 RIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
+K + I+I + E +EV + + I +Q+ ++ + +
Sbjct: 2797 TLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQEL--HAAEILDM 2854
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRE 614
R ++E E + ++ V+ + E
Sbjct: 2855 ESRHISETETLKREHYVAVQLLKEE 2879
Score = 34.3 bits (75), Expect = 1.4
Identities = 86/458 (18%), Positives = 187/458 (40%), Gaps = 39/458 (8%)
Query: 146 MQEIEKELDLYEKEVNLGSE-LRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++++++EL ++ ++ + L ++A + + IA+ L E + NE M F
Sbjct: 2368 IEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEM---TFM 2424
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ V ++ TN N L + L K R ES+ + + E S + ++ +
Sbjct: 2425 KN---VLKE-TNFKMNQLTQELFSLK-------RERESVEKIQSIPENSVNVAIDHLSKD 2473
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
P ++ + E F ++ K + I +E ++ + E+T
Sbjct: 2474 KPELEVVLTEDALKSLENQTYFKSFE-----ENGKGSIINLETRLLQLESTVSAKDLELT 2528
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
+ K+++ + + ++ K ++LQK ++++ Q + VQ + D
Sbjct: 2529 QCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQT 2588
Query: 385 VA----QRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRV----NELTVINVN- 434
++ + IQ+L E+ G+ AL ++ S +E Q E T + ++ + N
Sbjct: 2589 ISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNV 2648
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIA--DERYQRVQTELKHTVEHLHEEQERIVKIE 492
L K +E + + + + KE + + D + TEL H+ E E + +
Sbjct: 2649 LEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNE-LEALR 2707
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
A + + E+ + + E+++ +V + S L+ + + L E K E + IL
Sbjct: 2708 AESVATKAELASYKEKAEKLQEELLVKETNMTS-LQKDLSQVRDHLAEAK----EKLSIL 2762
Query: 553 RKK-ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
K+ E +++E C + I L + +T + I
Sbjct: 2763 EKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKI 2800
>AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20-7
protein.
Length = 623
Score = 61.3 bits (142), Expect = 1e-08
Identities = 82/453 (18%), Positives = 196/453 (43%), Gaps = 26/453 (5%)
Query: 149 IEKELDLYEKEVN--LGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQAS 206
+++EL ++EV + ++ A + K +A+ E +++ ER ++ + +
Sbjct: 118 LQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVA 177
Query: 207 RTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETV-RVRETSPTTCVVRINTEL 265
+Y +S+ K ES A+ + + +TE+ ++R+ R T +
Sbjct: 178 LEKSQSEYLKISQE---KEQQESLALEELELQKKAILTESENKLRDLQQEAETYR--TRI 232
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTR 325
+++S L E K K DL+V++ + +K + E E+ +
Sbjct: 233 LELESSLEKSLQENKNQSK---DLAVHLEAEKNKHNMEITVMVEKHKTELESLKHQQDAL 289
Query: 326 IKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGV 385
+KLQ+ + + ++ + ++T+ K + Q H +E+ + TL++ V
Sbjct: 290 WTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII--FQAHIEEMNEK---TLEKLDV 344
Query: 386 AQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTV-INVNLSSSKAKIEQ 444
Q ++SL+ E+ E+ L+ + +E++ + + +++ + + K +Q
Sbjct: 345 KQTELESLSSELSEV-------LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ 397
Query: 445 ELAIVAADYD-EITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVK 503
++ + +++ I + + ++ +++ LK +HL E Q + +EA K E E++
Sbjct: 398 QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQ 457
Query: 504 NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVI 563
S +L+ ++ ++ + E + + LD E R T K + + E Q K+V
Sbjct: 458 QASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLT-KQVAEVEAQKKDVC 516
Query: 564 IQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAE 596
+ + + + L LEK + ++ + L +
Sbjct: 517 TELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 549
Score = 53.6 bits (123), Expect = 2e-06
Identities = 81/450 (18%), Positives = 196/450 (43%), Gaps = 50/450 (11%)
Query: 241 ESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQ 300
E T + E + ++ ++ I+ + + L++ + + V ++ SS++
Sbjct: 80 EKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEE 139
Query: 301 TSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSL 360
++++L+ E +L + + KKLQ + E + + VA + + I ++
Sbjct: 140 QIAKLQKLH------EKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKE 193
Query: 361 QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEE 420
Q + E+Q++ +T ++ +++ L E E R + L ++ S+E+ +E
Sbjct: 194 QQESLALEELELQKKAILT-----ESENKLRDLQQEAETYR---TRILELESSLEKSLQE 245
Query: 421 SQTRVNELTVI--------NVNLSSSKAKIEQELAIVAADYDEI-TKELRIADERYQRVQ 471
++ + +L V N+ ++ K + EL + D + T++L++ ++YQ
Sbjct: 246 NKNQSKDLAVHLEAEKNKHNMEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQ--- 302
Query: 472 TELKHTVEHLHEEQERIVKIEAV----------KKSLE-IEVKNISVRLEEVEANAIVGG 520
TE++ E +E+E ++K + + +K+LE ++VK + E + ++
Sbjct: 303 TEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKA 362
Query: 521 KRIISKLEARIKD--------MELELDEEKRRHAETI-KILRKKERQLKEVIIQCEEDQK 571
+ + + + +KD +E ++DE+K H + + I+++ E ++ ++
Sbjct: 363 RHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN 422
Query: 572 NISLLQDSLEKTSQK----VSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES 627
+ LL +K ++ V + + EG QQ+ ++ FQ A ++ E
Sbjct: 423 QLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEE 482
Query: 628 NLSLIRAKHRTFVTTSTVPGSQVYLVQESR 657
L+ ++ K T + QV V+ +
Sbjct: 483 QLAQLQQKLLDLETERILLTKQVAEVEAQK 512
>AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring protein
AKAP350 protein.
Length = 3595
Score = 61.3 bits (142), Expect = 1e-08
Identities = 79/362 (21%), Positives = 166/362 (45%), Gaps = 32/362 (8%)
Query: 236 DSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILN 295
D +V S E ++ +ET + +NT++ + L ++L K +L I+
Sbjct: 3 DKKVENSNKEEIQEKET----IIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 58
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ + ++++E N++ + E + E+ K+L + EL+ ++ D+ + +
Sbjct: 59 KNQEIKNMKLELTNSK--QKERQSSEEI----KQLMGTVEELQKRNHKDSQFETDIVQRM 112
Query: 356 KKQSLQ-LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++++ + L +++ DE+ Q V + Q + Q Q + +G E ALR ++
Sbjct: 113 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRH-KGEMENALRSYSNI 171
Query: 415 ---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD-------YDEITKELRIAD 464
E Q + +NEL + + +S K K+++EL ++ + +++ +EL +
Sbjct: 172 TVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSR 231
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
E+ QR + + L+E + + +E +K EI + S + E++ A V +I
Sbjct: 232 EQIQRARQTIAEQESKLNEAHKSLSTVEDLK--AEIVSASESRKELELKHEAEVTNYKI- 288
Query: 525 SKLEARIKDMELELD---EEKRRHAETIK--ILRKKERQLKEVIIQCE-EDQKNISLLQD 578
KLE K+ LD E + E ++ +L E +L ++ E E + NI L+D
Sbjct: 289 -KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKD 347
Query: 579 SL 580
+L
Sbjct: 348 NL 349
Score = 56.4 bits (130), Expect = 3e-07
Identities = 105/512 (20%), Positives = 216/512 (42%), Gaps = 41/512 (8%)
Query: 145 RMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
R+QE+E E ++E L S RQK AM A + Q LL+E+ E++ K +
Sbjct: 1646 RLQELEAEQQQIQEERELLS--RQKEAMKA--EAGPVEQQLLQET------EKLMKEKLE 1695
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCV----VR 260
+ +D +L K V A + + ++ E TE + +R+ + +R
Sbjct: 1696 V-QCQAEKDRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMR 1754
Query: 261 INTELPAIDNSYLNQLNELKETVKQFDDLSVYI-LNDSSKQTSIEIEQLNARVVEAETKL 319
+ AID + + + +E K L V S+ + E+EQL A ++ +T
Sbjct: 1755 KFLDEQAIDREHERDVFQ-QEIQKLEQQLKVVPRFQPISEHQTREVEQL-ANHLKEKTDK 1812
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKT--IKKQSLQLTEIQTHYDEVQR--- 374
SE+ K++LQ I E ++ +L++ + + Q E + H+ V+
Sbjct: 1813 CSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPE 1872
Query: 375 -----QLQVTLDQYGVAQRRIQSLTGEVEEIR----GNYEQALRVKRSVEQQYEESQTRV 425
QLQ D ++ I +L ++E+ R E+ ++ +E Q +ES TR+
Sbjct: 1873 LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRL 1932
Query: 426 NELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQ 485
EL N K+ LAI +D T++ + ++ ++ E + ++ L+E+
Sbjct: 1933 QELEQENKLFKDDMEKL--GLAIKESDAMS-TQDQHVLFGKFAQIIQEKEVEIDQLNEQV 1989
Query: 486 ERI-VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISK-LEARIKDMELELDEEKR 543
++ +++ + IE KN +R E + ++ + + + E I+ + +++ ++
Sbjct: 1990 TKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ 2049
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNI----SLLQDSLEKTSQKVSIYKRQLAEQEG 599
A + L E + + L+ +E +++++ K L E
Sbjct: 2050 ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNF 2109
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
Q + +RE E+ E + E+++++
Sbjct: 2110 KMNQLTQELFSLKRERESVEKIQSIPENSVNV 2141
Score = 42.3 bits (95), Expect = 0.005
Identities = 92/431 (21%), Positives = 190/431 (44%), Gaps = 54/431 (12%)
Query: 157 EKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRDYTN 216
E EV S+ + + +RG+ A+ Q LEE R+V ++ + A T N
Sbjct: 2694 EAEVYDSSQSHESFSDWRGELLLALQQVFLEE--RSVL-LAAFRTELTALGTTDAVGLLN 2750
Query: 217 -LSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQ 275
L + + + + AM S+ ++ + + E + S +
Sbjct: 2751 CLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPS--QE 2808
Query: 276 LNELKETVKQFDDLSVYILNDSSKQTSIEI-EQLNA-RVVEAETKLKSEVTRIKKKLQI- 332
L E KQ L + + S K + E+ EQL++ ++V AE LKSE+ + K +L+
Sbjct: 2809 LLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAE--LKSELAQTKLELETT 2866
Query: 333 ------QITELE-LSLDVANKT----------------NIDLQKTIKKQSLQLTEIQTHY 369
+ ELE L+V +KT + +LQ ++K+ +L +
Sbjct: 2867 LKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERD 2926
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV-EQQYEESQTRVNEL 428
E L+ +L+ ++ L + +++ +Q + +R + + Q E Q R EL
Sbjct: 2927 KEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLEL 2986
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQR---VQTE--LKHTVEHLHE 483
V+ L S K +I +E++ E+ +L+ +D Q + +E LK + L E
Sbjct: 2987 QVL---LESEKVRI-REMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEE 3042
Query: 484 EQERIV---------KIEAVKKSLEIEV-KNISVRLEEVEANAIVGGKRIISKLEARIKD 533
+ RIV K+++++ ++E + + + + E A G++ + +L+++++D
Sbjct: 3043 KHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVED 3102
Query: 534 MELELDEEKRR 544
++ +L+E++++
Sbjct: 3103 LQRQLEEKRQQ 3113
Score = 39.1 bits (87), Expect = 0.049
Identities = 61/364 (16%), Positives = 157/364 (43%), Gaps = 19/364 (5%)
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+++ TEL ++ + N+L+E Q + + IL D K+T ++ +++ V + E
Sbjct: 438 LQLKTEL--LEKQMKEKENDLQEKFAQLEAENS-ILKDE-KKTLEDMLKIHTPVSQEERL 493
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ + + K K + E+E+ ++ N DL++ + + ++ + + + ++ +V
Sbjct: 494 IFLDSIKSKSKDSVWEKEIEILIE----ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 549
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVN--L 435
+ + + ++E+ + +Q L K ++ EE R+N TV +
Sbjct: 550 NYQELQEEYACLLKVKDDLEDSKN--KQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 607
Query: 436 SSSKAKIEQELA---IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
K + + L +V D E+ ++L + + L E L ++ I +
Sbjct: 608 DEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLN 667
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE-TIKI 551
KSL+ E + +S+R E+E + + ++ + + R AE ++
Sbjct: 668 EEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSK 727
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
+ K + +++++ + +N+++ ++S K Q + + + ++ + + +
Sbjct: 728 VNKSFGEESKIMVEDKVSFENMTVGEES--KQEQLILDHLPSVTKESSLRATQPSENDKL 785
Query: 612 QREL 615
Q+EL
Sbjct: 786 QKEL 789
Score = 37.9 bits (84), Expect = 0.11
Identities = 32/144 (22%), Positives = 76/144 (52%), Gaps = 7/144 (4%)
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGG--KRIISKLEARIKDMELELDE 540
+E+E I++ E K +E E K + ++ + A+ ++G ++I+ K + IK+M+LEL
Sbjct: 15 QEKETIIE-ELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQ-EIKNMKLELTN 72
Query: 541 EKRRHAETIKILRKKERQLKEVIIQCEED-QKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
K++ ++ + +++ ++E+ + +D Q ++Q ++T +K+ + +L E G
Sbjct: 73 SKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYG 132
Query: 600 MS--QQSVTRVRRFQRELEAAEDR 621
Q +R+ ++E + R
Sbjct: 133 QQIVQMKQELIRQHMAQMEEMKTR 156
Score = 35.5 bits (78), Expect = 0.61
Identities = 52/276 (18%), Positives = 117/276 (42%), Gaps = 30/276 (10%)
Query: 331 QIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRI 390
Q Q+ E+++ L +LQ+ + + + + E+++ + + +L+ TL + +
Sbjct: 2818 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLK---AQHKHL 2874
Query: 391 QSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVA 450
+ L E++ ++ + ++ + ++S+ L L S+ + ++EL
Sbjct: 2875 KELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEEL---- 2930
Query: 451 ADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLE 510
+++ L +R ++ L+ + L+E Q+ KIE+ + + ++ R
Sbjct: 2931 ---EDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQ---KIESQRMLYDAQLSEEQGRNL 2984
Query: 511 EVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE--------TIKILRKKERQLKEV 562
E++ ++ + RI++M LD E+ HA+ + E LKE+
Sbjct: 2985 ELQV--------LLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKEL 3036
Query: 563 IIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
Q EE I L + EK S+ RQ E++
Sbjct: 3037 QKQLEEKHSRIVELLNETEKYKLD-SLQTRQQMEKD 3071
Score = 34.7 bits (76), Expect = 1.1
Identities = 66/325 (20%), Positives = 136/325 (41%), Gaps = 25/325 (7%)
Query: 300 QTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQS 359
Q +E Q A+ + + SE R + Q+ E EL D++ T++
Sbjct: 2246 QIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDIS-------ALTLRISE 2298
Query: 360 LQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI-RGNYE-QALRVKRSVEQQ 417
L+ ++ H + + QV + + V ++ + L E++++ GN + Q + K+ Q
Sbjct: 2299 LESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLL--ELQKLLEGNEKKQREKEKKRSPQD 2356
Query: 418 YEESQTRV-----NELTVINVNLSSSKAK---IEQELAIVAADYDEITKELRIADERYQR 469
E +T NE + L + +A+ + ELA +++ +EL + +
Sbjct: 2357 VEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTS 2416
Query: 470 VQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEA 529
+Q +L +HL E +E K+ ++K E EV+ S + E I K I S+ +
Sbjct: 2417 LQKDLSQVRDHLAEAKE---KLSILEKEDETEVQE-SKKACMFEPLPIKLSKSIASQTDG 2472
Query: 530 RIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
+K + I+I + E +EV + + I +Q+ ++ + +
Sbjct: 2473 TLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQEL--HAAEILDM 2530
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRE 614
R ++E E + ++ V+ + E
Sbjct: 2531 ESRHISETETLKREHYVAVQLLKEE 2555
Score = 34.3 bits (75), Expect = 1.4
Identities = 86/458 (18%), Positives = 187/458 (40%), Gaps = 39/458 (8%)
Query: 146 MQEIEKELDLYEKEVNLGSE-LRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQ 204
++++++EL ++ ++ + L ++A + + IA+ L E + NE M F
Sbjct: 2044 IEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEM---TFM 2100
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
+ V ++ TN N L + L K R ES+ + + E S + ++ +
Sbjct: 2101 KN---VLKE-TNFKMNQLTQELFSLK-------RERESVEKIQSIPENSVNVAIDHLSKD 2149
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVT 324
P ++ + E F ++ K + I +E ++ + E+T
Sbjct: 2150 KPELEVVLTEDALKSLENQTYFKSFE-----ENGKGSIINLETRLLQLESTVSAKDLELT 2204
Query: 325 RIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYG 384
+ K+++ + + ++ K ++LQK ++++ Q + VQ + D
Sbjct: 2205 QCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQT 2264
Query: 385 VA----QRRIQSLTGEVEEIRGNYEQALRVKRS-VEQQYEESQTRV----NELTVINVN- 434
++ + IQ+L E+ G+ AL ++ S +E Q E T + ++ + N
Sbjct: 2265 ISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNV 2324
Query: 435 LSSSKAKIEQELAIVAADYDEITKELRIA--DERYQRVQTELKHTVEHLHEEQERIVKIE 492
L K +E + + + + KE + + D + TEL H+ E E + +
Sbjct: 2325 LEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNE-LEALR 2383
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKIL 552
A + + E+ + + E+++ +V + S L+ + + L E K E + IL
Sbjct: 2384 AESVATKAELASYKEKAEKLQEELLVKETNMTS-LQKDLSQVRDHLAEAK----EKLSIL 2438
Query: 553 RKK-ERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
K+ E +++E C + I L + +T + I
Sbjct: 2439 EKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKI 2476
>AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein.
Length = 1642
Score = 61.3 bits (142), Expect = 1e-08
Identities = 79/362 (21%), Positives = 166/362 (45%), Gaps = 32/362 (8%)
Query: 236 DSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILN 295
D +V S E ++ +ET + +NT++ + L ++L K +L I+
Sbjct: 325 DKKVENSNKEEIQEKET----IIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 380
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ + ++++E N++ + E + E+ K+L + EL+ ++ D+ + +
Sbjct: 381 KNQEIKNMKLELTNSK--QKERQSSEEI----KQLMGTVEELQKRNHKDSQFETDIVQRM 434
Query: 356 KKQSLQ-LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++++ + L +++ DE+ Q V + Q + Q Q + +G E ALR ++
Sbjct: 435 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRH-KGEMENALRSYSNI 493
Query: 415 ---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD-------YDEITKELRIAD 464
E Q + +NEL + + +S K K+++EL ++ + +++ +EL +
Sbjct: 494 TVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSR 553
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
E+ QR + + L+E + + +E +K EI + S + E++ A V +I
Sbjct: 554 EQIQRARQTIAEQESKLNEAHKSLSTVEDLK--AEIVSASESRKELELKHEAEVTNYKI- 610
Query: 525 SKLEARIKDMELELD---EEKRRHAETIK--ILRKKERQLKEVIIQCE-EDQKNISLLQD 578
KLE K+ LD E + E ++ +L E +L ++ E E + NI L+D
Sbjct: 611 -KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKD 669
Query: 579 SL 580
+L
Sbjct: 670 NL 671
Score = 51.6 bits (118), Expect = 9e-06
Identities = 67/366 (18%), Positives = 163/366 (44%), Gaps = 28/366 (7%)
Query: 258 VVRINTELPAIDNSY----LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVV 313
+ +N EL + +Y L QL E + +KQ D + Q + ++Q AR
Sbjct: 183 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIIT--------QLTANLQQ--ARRE 232
Query: 314 EAETKLKS-EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
+ ET + E+T +KLQIQ +L+ S + N T+ + + Q I TH ++
Sbjct: 233 KDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQ---ILTHQQQL 289
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIR-GNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+ Q + D + ++ E+I+ EQ +V+ S +++ +E +T + EL
Sbjct: 290 EEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTK 349
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI 491
+ +++ +L E+ +++ ++ + ++ EL ++ + + E I ++
Sbjct: 350 IIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQL 409
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK- 550
+ E++ +N + + E + + +R+ + + +++ + ELDE + +K
Sbjct: 410 MGTVE--ELQKRN--HKDSQFETDIV---QRMEQETQRKLEQLRAELDEMYGQQIVQMKQ 462
Query: 551 -ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
++R+ Q++E+ + + + +N ++ ++ + + E Q + ++
Sbjct: 463 ELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE 522
Query: 610 RFQREL 615
+ + EL
Sbjct: 523 KLKEEL 528
Score = 35.5 bits (78), Expect = 0.61
Identities = 71/396 (17%), Positives = 167/396 (42%), Gaps = 34/396 (8%)
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+++ TEL ++ + N+L+E Q + + IL D K+T ++ +++ V + E
Sbjct: 760 LQLKTEL--LEKQMKEKENDLQEKFAQLEAENS-ILKDE-KKTLEDMLKIHTPVSQEERL 815
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ + + K K + E+E+ ++ N DL++ + + ++ + + + ++ +V
Sbjct: 816 IFLDSIKSKSKDSVWEKEIEILIE----ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 871
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVN--L 435
+ + + ++E+ + +Q L K ++ EE R+N TV +
Sbjct: 872 NYQELQEEYACLLKVKDDLEDSKN--KQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 929
Query: 436 SSSKAKIEQELA---IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
K + + L + D E+ ++L + + L E L + I +
Sbjct: 930 DEDKTFVAETLEMGEVXEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKPKPGEISFLN 989
Query: 493 AVKKSLEIEVKNISVRLEEVE--------ANAIVGGKRIISKLEARI----KDMELELDE 540
KSL+ E + +S+R E+E N ++ S L+ + + E + +
Sbjct: 990 EEVKSLKPEKEPVSLRCRELEIIINHNRAENVXSCDTQVSSLLDGVVTMTSRGAEGSVSK 1049
Query: 541 EKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGM 600
+ E KI+ + + + + + E+ K L+ D L +++ S+ Q +E + +
Sbjct: 1050 VNKSFGEESKIMVEDKVSFENMTV--GEESKQEQLILDHLPSVTKESSLRATQPSENDKL 1107
Query: 601 SQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
Q+ + ++ Q +L + + LSL+ + H
Sbjct: 1108 -QKELNVLKSEQNDLRLQMEAQRIC---LSLVYSTH 1139
>AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein.
Length = 1620
Score = 61.3 bits (142), Expect = 1e-08
Identities = 79/362 (21%), Positives = 166/362 (45%), Gaps = 32/362 (8%)
Query: 236 DSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILN 295
D +V S E ++ +ET + +NT++ + L ++L K +L I+
Sbjct: 294 DKKVENSNKEEIQEKET----IIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 349
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ + ++++E N++ + E + E+ K+L + EL+ ++ D+ + +
Sbjct: 350 KNQEIKNMKLELTNSK--QKERQSSEEI----KQLMGTVEELQKRNHKDSQFETDIVQRM 403
Query: 356 KKQSLQ-LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
++++ + L +++ DE+ Q V + Q + Q Q + +G E ALR ++
Sbjct: 404 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRH-KGEMENALRSYSNI 462
Query: 415 ---EQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD-------YDEITKELRIAD 464
E Q + +NEL + + +S K K+++EL ++ + +++ +EL +
Sbjct: 463 TVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSR 522
Query: 465 ERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRII 524
E+ QR + + L+E + + +E +K EI + S + E++ A V +I
Sbjct: 523 EQIQRARQTIAEQESKLNEAHKSLSTVEDLK--AEIVSASESRKELELKHEAEVTNYKI- 579
Query: 525 SKLEARIKDMELELD---EEKRRHAETIK--ILRKKERQLKEVIIQCE-EDQKNISLLQD 578
KLE K+ LD E + E ++ +L E +L ++ E E + NI L+D
Sbjct: 580 -KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKD 638
Query: 579 SL 580
+L
Sbjct: 639 NL 640
Score = 51.6 bits (118), Expect = 9e-06
Identities = 67/366 (18%), Positives = 163/366 (44%), Gaps = 28/366 (7%)
Query: 258 VVRINTELPAIDNSY----LNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVV 313
+ +N EL + +Y L QL E + +KQ D + Q + ++Q AR
Sbjct: 152 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIIT--------QLTANLQQ--ARRE 201
Query: 314 EAETKLKS-EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEV 372
+ ET + E+T +KLQIQ +L+ S + N T+ + + Q I TH ++
Sbjct: 202 KDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQ---ILTHQQQL 258
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIR-GNYEQALRVKRSVEQQYEESQTRVNELTVI 431
+ Q + D + ++ E+I+ EQ +V+ S +++ +E +T + EL
Sbjct: 259 EEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTK 318
Query: 432 NVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI 491
+ +++ +L E+ +++ ++ + ++ EL ++ + + E I ++
Sbjct: 319 IIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQL 378
Query: 492 EAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK- 550
+ E++ +N + + E + + +R+ + + +++ + ELDE + +K
Sbjct: 379 MGTVE--ELQKRN--HKDSQFETDIV---QRMEQETQRKLEQLRAELDEMYGQQIVQMKQ 431
Query: 551 -ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
++R+ Q++E+ + + + +N ++ ++ + + E Q + ++
Sbjct: 432 ELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE 491
Query: 610 RFQREL 615
+ + EL
Sbjct: 492 KLKEEL 497
Score = 39.1 bits (87), Expect = 0.049
Identities = 61/364 (16%), Positives = 157/364 (43%), Gaps = 19/364 (5%)
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+++ TEL ++ + N+L+E Q + + IL D K+T ++ +++ V + E
Sbjct: 729 LQLKTEL--LEKQMKEKENDLQEKFAQLEAENS-ILKDE-KKTLEDMLKIHTPVSQEERL 784
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
+ + + K K + E+E+ ++ N DL++ + + ++ + + + ++ +V
Sbjct: 785 IFLDSIKSKSKDSVWEKEIEILIE----ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEV 840
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVN--L 435
+ + + ++E+ + +Q L K ++ EE R+N TV +
Sbjct: 841 NYQELQEEYACLLKVKDDLEDSKN--KQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 898
Query: 436 SSSKAKIEQELA---IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
K + + L +V D E+ ++L + + L E L ++ I +
Sbjct: 899 DEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLN 958
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAE-TIKI 551
KSL+ E + +S+R E+E + + ++ + + R AE ++
Sbjct: 959 EEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSK 1018
Query: 552 LRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRF 611
+ K + +++++ + +N+++ ++S K Q + + + ++ + + +
Sbjct: 1019 VNKSFGEESKIMVEDKVSFENMTVGEES--KQEQLILDHLPSVTKESSLRATQPSENDKL 1076
Query: 612 QREL 615
Q+EL
Sbjct: 1077 QKEL 1080
>AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein.
Length = 948
Score = 61.3 bits (142), Expect = 1e-08
Identities = 94/488 (19%), Positives = 205/488 (42%), Gaps = 35/488 (7%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSE-LRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKP 201
+K ++E+E ++ ++ +N E +++ M + K A A E R + M+
Sbjct: 285 RKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVH 344
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC---V 258
++ L ++ +N + + M + N+ DS T+++ + ++++ ++ +
Sbjct: 345 HLES--LLEQKE----KENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGL 398
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVY--ILNDSSKQTSIEIEQLNARVVEAE 316
+ E+ + ++ E +E +KQ + + + + Q E+ + + ++ +
Sbjct: 399 RDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQ 458
Query: 317 TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQL 376
TKL++ + Q I L+ SL + LQ + L+L E +T ++ +Q+
Sbjct: 459 TKLETLTNQFSDSKQ-HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQI 517
Query: 377 QVTLDQYGVAQRRIQSLTG--EVEEIRGNY-----EQALRVKRSVEQQYEESQTRVNELT 429
Q ++ G I L +V+E + N E R E+Q + RV L
Sbjct: 518 QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 577
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADER--------YQRVQTELKHTVE-- 479
N ++ +E+ LA + + KE R DER Y++ +LK V
Sbjct: 578 ADTTNTDTALTTLEEALAEKERTIERL-KEQRDRDEREKQEEIDNYKKDLKDLKEKVSLL 636
Query: 480 --HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELE 537
L E++ ++ ++ SL RL+ +E A+ K K+E+++K E
Sbjct: 637 QGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEI-ALEQKKEECLKMESQLKKAH-E 694
Query: 538 LDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQ 597
E R E ++ ER++ + + Q + L + L++ + + +++AE
Sbjct: 695 AALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAEL 754
Query: 598 EGMSQQSV 605
E ++ + V
Sbjct: 755 ESLTSRQV 762
Score = 52.8 bits (121), Expect = 4e-06
Identities = 86/456 (18%), Positives = 207/456 (45%), Gaps = 27/456 (5%)
Query: 202 DFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVV-R 260
D Q V R+ L K+V K S +MNS + + + + +R+ + + +
Sbjct: 153 DLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWK 212
Query: 261 INTELPAIDNSYLNQ-LNELKETVKQFDDLSVYILNDSSKQTS----IEIEQLNARVVEA 315
+ +N ++ + L++ ++ DL+ DSS +T E+ + N + + A
Sbjct: 213 EQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHA 272
Query: 316 ETKLKS-EVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKK--QSLQLTEIQTHYDEV 372
E + ++ E+ ++K L+ E+EL ++ +T ++IKK + LQ + E
Sbjct: 273 EHERQAKELFLLRKTLE----EMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEE 328
Query: 373 QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN 432
+ L + + ++SL + E+ + + R E + ++T+ + TVI
Sbjct: 329 DHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMH--RRFENAPDSAKTKALQ-TVIE 385
Query: 433 VNLS--SSKAK----IEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQE 486
+ S SS + +E+E+ ++ ++ T+E ++ + ++ K + + ++
Sbjct: 386 MKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQ 445
Query: 487 RIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
+ + + +L+ +++ ++ + + + + V + + +K E R ++ E+D + R
Sbjct: 446 ELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAK-EQRAAILQTEVDALRLRLE 504
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ---LAEQEGMSQQ 603
E +L KK +Q++++ + I L+D L+ +KV++ +++ L EQ ++
Sbjct: 505 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 604 SVTRVRRFQRELEAAEDRADVAESNL-SLIRAKHRT 638
++ ++ + L+A D A + L + K RT
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT 600
Score = 48.4 bits (110), Expect = 8e-05
Identities = 106/557 (19%), Positives = 221/557 (39%), Gaps = 39/557 (7%)
Query: 85 AEQAKRDLNTFTVGKRSPFSVIATA--AAANVTKHVGVESVTVXXXXXXXXXXXXXXXXQ 142
+E K + G R P+ V TA ++ N+ GV S T+
Sbjct: 82 SETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASS-GVASDTIAFGEHHLPPVSMASTVP 140
Query: 143 KKRMQEIEK---ELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMY 199
Q + +L KEV ++L +K + + ++ ++ ER
Sbjct: 141 HSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERAL 200
Query: 200 KPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPT--TC 257
+ D +AS+ + ++ + + M +A+ + R+ + + + +S T C
Sbjct: 201 RKD-EASKITIWKEQYRVVQEENQHMQMTIQALQD-ELRIQRDLNQLFQQDSSSRTGEPC 258
Query: 258 VVRINTE----LPAIDNSYLNQLNELKETVKQFD---DLSVYILNDSSKQTSIEIEQLNA 310
V + E L A +L L++T+++ + + LN + +E L +
Sbjct: 259 VAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS 318
Query: 311 RVVEAE-TKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY 369
+ + A+ T+ E TR + ++ + LE L+ K N L++ + ++ +
Sbjct: 319 KGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPD-SAKT 377
Query: 370 DEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELT 429
+Q +++ + +R ++ L E++ ++ N AL S E++ EE + ++
Sbjct: 378 KALQTVIEMKDSKISSMERGLRDLEEEIQMLKSN--GAL----STEEREEE----MKQME 427
Query: 430 VINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV 489
V + K KI Q V + EL + + + + + +H+ +E +
Sbjct: 428 VYRSHSKFMKNKIGQ----VKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 483
Query: 490 KIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR------IKDMELELDEEKR 543
E L+ EV + +RLEE E K+I E + I D++ LD ++R
Sbjct: 484 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 543
Query: 544 RHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
+ K + + QL++ Q ++ + LQ T ++ + LAE+E ++
Sbjct: 544 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIER 603
Query: 604 SVTRVRRFQRELEAAED 620
+ R +RE + D
Sbjct: 604 LKEQRDRDEREKQEEID 620
Score = 46.4 bits (105), Expect = 3e-04
Identities = 93/501 (18%), Positives = 202/501 (40%), Gaps = 52/501 (10%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAM-YRGKSAKAIAQTLLEES--RRNVQNERMYKPDF 203
Q ++ + + E+ + +L Q ++ + L EE+ R + ++ER K F
Sbjct: 223 QHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELF 282
Query: 204 QASRTLVNRDY-------TNLSKNVLAKALMESKAMNSCDSRVTESITE-TVRVRETSPT 255
+TL + T +++ K L+E ++ TE E T R+ E
Sbjct: 283 LLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMH 342
Query: 256 TCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEA 315
+ E +NS L + E+ + D + + QT IE++ +E
Sbjct: 343 VHHLESLLEQKEKENSMLRE--EMHRRFENAPDSA----KTKALQTVIEMKDSKISSMER 396
Query: 316 ETK-LKSEVTRIKKKLQIQITELE---LSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDE 371
+ L+ E+ +K + E E ++V + ++ I + +L+ T
Sbjct: 397 GLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLA 456
Query: 372 VQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ---QYEESQTRVNEL 428
+Q +L+ +Q+ +++ I+ L E + ++A ++ V+ + EE +T +N+
Sbjct: 457 LQTKLETLTNQFSDSKQHIEVLK---ESLTAKEQRAAILQTEVDALRLRLEEKETMLNKK 513
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
T + +E A + ++ L + + + +Q ++++ E L ++++++
Sbjct: 514 T-------KQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQM 566
Query: 489 VKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAET 548
++ KSL+ + N L +E A+ +R I +L+ + D ++R E
Sbjct: 567 SSLKERVKSLQADTTNTDTALTTLE-EALAEKERTIERLKE-------QRDRDEREKQEE 618
Query: 549 IKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRV 608
I +K + LKE +SLLQ L + + K + + +R+
Sbjct: 619 IDNYKKDLKDLKE----------KVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRL 668
Query: 609 RRFQRELEAAEDRADVAESNL 629
+ + LE ++ ES L
Sbjct: 669 KTLEIALEQKKEECLKMESQL 689
Score = 33.1 bits (72), Expect = 3.2
Identities = 56/322 (17%), Positives = 146/322 (45%), Gaps = 26/322 (8%)
Query: 147 QEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTL-LEESRRNVQNERMYKPDFQA 205
+E ++E+D Y+K++ +L++K ++ +G ++ A L L+E ++ + + K
Sbjct: 613 REKQEEIDNYKKDLK---DLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLK 669
Query: 206 SRTLV---NRDYTNLSKNVLAKA---LMESKAMNSCDSRVTESITETVRVRETSPTTC-- 257
+ + ++ ++ L KA +E++A R+ E R ++ S
Sbjct: 670 TLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAE 729
Query: 258 VVRINTELPAIDNSYLNQLNELKE----TVKQFDDLSVYILNDSSKQTSIEIEQLNARVV 313
V R+ L ++N ++ ++ E T +Q D + + N K+ +E ++ +A+++
Sbjct: 730 VDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKE-QVE-KKKSAQML 787
Query: 314 EAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
E + + + ++LQ++ EL ++++ + ++ + L E +TH ++
Sbjct: 788 EEARRREDNLNDSSQQLQVE--ELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLR 845
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
+ + L++ V + + ++L + E N L + S ++ EE E +
Sbjct: 846 AERRKHLEE--VLEMKQEALLAAISEKDANI-ALLELSSSKKKTQEEVAALKREKDRL-- 900
Query: 434 NLSSSKAKIEQELAIVAADYDE 455
+ K + + + ++A +Y++
Sbjct: 901 -VQQLKQQTQNRMKLMADNYED 921
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 60.9 bits (141), Expect = 1e-08
Identities = 89/501 (17%), Positives = 214/501 (42%), Gaps = 32/501 (6%)
Query: 143 KKRMQEIEKELDLYEKE-VNLGSELRQKAAMYRGKSAK-AIAQTLLEESRRNVQNERMYK 200
K +++E+ + L ++E + V L SE + K + + LL + ++ + +
Sbjct: 91 KTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSQLEEKEQAE 150
Query: 201 PDF-QASRTLVNRDYTNLSK-NVLAKALM-ESKAMNSCDSRVTESITETVRVRETSPTTC 257
+ S+T V L + N AL + + M + + + I E ++R +
Sbjct: 151 IQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS----- 205
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNAR--VVEA 315
+ ++ L A + L L +LKE+ D L + N + +EI + N +EA
Sbjct: 206 IEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVEN---LERELEIARTNQEHAALEA 262
Query: 316 ETKLKSEVTRIKKKLQIQITELE-LSLDVAN--KTNIDLQKTIKKQSLQLTEIQ---THY 369
E K EV +K K++ L L LDV DL ++K+ +++E++ + +
Sbjct: 263 ENS-KGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEIINSSF 321
Query: 370 DEV-QRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNEL 428
+ + Q + Q + + ++ L +++ ++ + K+ V + + ++V L
Sbjct: 322 ENILQEKEQEKVQMKEKSSTAMEMLQTQLKSSMREWQPCIMTKKPVSAKEQNLSSQVECL 381
Query: 429 TVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERI 488
+ L + + ++ + + + +E+ ++ ++ E+ + ++++ +
Sbjct: 382 ELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLV 441
Query: 489 VKIEAVK------KSLEIEVKNISVRLEE---VEANAIVGGKRIISKLEARIKDMELELD 539
K+ V+ K +E++N++V LE+ V + + + L++ K++E EL+
Sbjct: 442 SKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELE 501
Query: 540 EEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
K ++ + K + E+ + E + + LQ+ L +++ + L E+
Sbjct: 502 LTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIK 561
Query: 600 MSQQSVTRVRRFQRELEAAED 620
S+ + + EL+ + D
Sbjct: 562 SSKDQLKELTLENSELKKSLD 582
Score = 51.6 bits (118), Expect = 9e-06
Identities = 67/394 (17%), Positives = 175/394 (44%), Gaps = 27/394 (6%)
Query: 222 LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYLNQLNELKE 281
+A+ L E N E++ +++ E + ++ ++ + Q+ E+
Sbjct: 41 IAEKLKERDGENDSLKDKVENLERELQMSEENQELVILDAENSKAEVE-TLKTQIEEMAR 99
Query: 282 TVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSL 341
++K F+ L + L + + +I++ ++ E + L S +++++K Q +I E S
Sbjct: 100 SLKVFE-LDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSQLEEKEQAEIQIKEES- 157
Query: 342 DVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR 401
KT +++ + K+ + E+ + + +LD + ++++ +E++R
Sbjct: 158 ----KTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRN---SIEKLR 210
Query: 402 GNYEQALRVKRSVEQQYEESQTRVN-----------ELTVINVNLSSSKAKIEQ---ELA 447
E + + V QQ +ES+ + EL + N + + E E+
Sbjct: 211 ARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVE 270
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ A + +T+ LR + +++E + L +EQERI ++E + S E ++
Sbjct: 271 TLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEIINSSFENILQEKEQ 330
Query: 508 RLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKI---LRKKERQLKEVII 564
+++ + + + ++L++ +++ + + +K A+ + + E + +++
Sbjct: 331 EKVQMKEKSSTAMEMLQTQLKSSMREWQPCIMTKKPVSAKEQNLSSQVECLELEKAQLLQ 390
Query: 565 QCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
+E + N +LQ S+ Q+V K++L +++
Sbjct: 391 GLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKD 424
Score = 46.8 bits (106), Expect = 2e-04
Identities = 70/319 (21%), Positives = 140/319 (43%), Gaps = 13/319 (4%)
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAETKLKSE 322
L + +SY N NEL+ T + ++K+T + E+ ++ + E + +L E
Sbjct: 486 LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGE 545
Query: 323 VTRIKKKLQIQITELELSLDVANKT---NIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
R+ +LQ+ + E++ S D + N +L+K++ E + E + Q+
Sbjct: 546 KNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR 605
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVNLSSS 438
L + A+++ Q+L + + Q R K + +++ SQ ++ L L++S
Sbjct: 606 LHE---AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNS 662
Query: 439 -KA--KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
KA +I +EL D + +L+ +ER Q L + + L EE+E + K +
Sbjct: 663 LKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQL 722
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
++ + + K +V +V+ K + LE + K+ + LD+ K+ + K
Sbjct: 723 QAAQEKQKTGTVMDTKVD-ELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAK 781
Query: 556 ERQLKEVIIQCEEDQKNIS 574
E +V C + K S
Sbjct: 782 EMLETQVAHLCSQQSKQDS 800
Score = 44.0 bits (99), Expect = 0.002
Identities = 104/535 (19%), Positives = 235/535 (43%), Gaps = 56/535 (10%)
Query: 144 KRMQEIEKELDLYEKEV-NLGSELR-----QKAAMYRGKSAKAIAQTLLEESRRNVQNER 197
++++E E DL + V NL EL Q+ A +++K +TL + Q+ R
Sbjct: 225 QQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLR 284
Query: 198 MYKPDFQASRTLVNRDYTN-LSKNVLAKALMESKAMNSC-DSRVTESITETVRVRETSPT 255
+ D R+ D TN L K + + E + +NS ++ + E E V+++E S +
Sbjct: 285 GLELDVVTIRS-EKEDLTNELQKE--QERISELEIINSSFENILQEKEQEKVQMKEKS-S 340
Query: 256 TCVVRINTELPAIDNSYLNQLNELKETVKQFDDLSVYI----LNDSSKQTSIEIEQLNAR 311
T + + T+L + + + K + +LS + L + ++ + N
Sbjct: 341 TAMEMLQTQLKSSMREWQPCIMTKKPVSAKEQNLSSQVECLELEKAQLLQGLDEAKNNYI 400
Query: 312 VVEAETK-LKSEVTRIKKKLQI---QITELELSLD-----VANKTNIDLQKTI-KKQSLQ 361
V+++ L EV K+KL+ +I+ L+ + V+ + ++ + + K+Q+L+
Sbjct: 401 VLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLE 460
Query: 362 LTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEES 421
L + E+++++QV + Q ++ L + + E K S ++ +
Sbjct: 461 LRNLTV---ELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKM 517
Query: 422 QTRVNELTVINVNLSSSKAKIEQELA----IVAADYDEITKELRIADERYQRV---QTEL 474
+ EL ++ A++++EL+ +A + + +E++ + ++ + + +EL
Sbjct: 518 TAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSEL 577
Query: 475 KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM 534
K +++ +H++Q +E K E E+ +RL E E K+ + L K
Sbjct: 578 KKSLDCMHKDQ-----VEKEGKVRE-EIAEYQLRLHEAE-------KKHQALLLDTNKQY 624
Query: 535 ELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL-----LQDSLEKTSQKVSI 589
E+E+ + + + L ++ ++ +++ +++ N SL + + L+KT
Sbjct: 625 EVEIQTYREKLTSKEECLSSQKLEID--LLKSSKEELNNSLKATTQILEELKKTKMDNLK 682
Query: 590 YKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTST 644
Y QL ++ +Q + + + ++LE ++ S L + K +T T
Sbjct: 683 YVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDT 737
Score = 40.7 bits (91), Expect = 0.016
Identities = 57/277 (20%), Positives = 130/277 (46%), Gaps = 30/277 (10%)
Query: 329 KLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQR 388
+L+ I +L + ++ K + + + +K++ + ++ + ++R+LQ++ + +
Sbjct: 19 QLRRGIEKLRVRIEADEKKQLHIAEKLKERDGENDSLKDKVENLERELQMSEENQELVIL 78
Query: 389 RIQSLTGEVEEIRGNYEQ---ALRV-----------KRSVEQQYEESQTRVNELTVINVN 434
++ EVE ++ E+ +L+V K ++ +Q +E Q +++EL +
Sbjct: 79 DAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKL--- 135
Query: 435 LSSSKAKIEQ-ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEA 493
LSS K+++E+ E A + +I +E + A E Q EL V L +QE I+K A
Sbjct: 136 LSSFKSQLEEKEQAEI-----QIKEESKTAVEMLQNQLKELNEAVAALCGDQE-IMK--A 187
Query: 494 VKKSLEIEVK---NISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIK 550
++SL+ ++ + +E++ A K+ + L+ ++K+ E D K R +
Sbjct: 188 TEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQ-QLKESEHHADLLKGRVENLER 246
Query: 551 ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
L + ++ E + + L+ +E +Q +
Sbjct: 247 ELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSL 283
>AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein
protein.
Length = 1177
Score = 60.9 bits (141), Expect = 1e-08
Identities = 86/385 (22%), Positives = 182/385 (47%), Gaps = 38/385 (9%)
Query: 273 LNQLNE-LKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAE------TKLKSEV 323
L ++N+ L++ ++ +L I +S+ E+E L RV+E E TK +S+
Sbjct: 345 LEEINKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 404
Query: 324 TRIKKKLQIQ---ITELELSLDVANKTNIDLQK---TIKKQSLQLTEIQTHYDEVQRQLQ 377
++KKLQ + EL L ++ K +L+K K + T++ + ++ + +
Sbjct: 405 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQYEESQTRVNELTVINVNLS 436
L++ V + R++ L E E R E+A L +K + + + V+E + +
Sbjct: 465 DLLNELEVVKSRVKEL--ECSESR--LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIK 520
Query: 437 SSKAKIE---QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV---K 490
+ K++ + + ++T++L ++ ++++E++ V +L E++ ++ K
Sbjct: 521 QEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLK 580
Query: 491 IEAVKKS-LEIEVKNISVRL---EEVEANAIVGGKRIISKL----EARIKDMELELDEEK 542
E K S L V + RL EEVE G R S+L + +IK++ LE++ K
Sbjct: 581 SEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLK 640
Query: 543 RR--HAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+R E ++ L K E + ++ + +Q + L LE+ +++ + + + E
Sbjct: 641 KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIA-KNKAIEKGEV 699
Query: 600 MSQQSVTRVRRFQRELEAAEDRADV 624
+SQ++ R R E ++ + +A+V
Sbjct: 700 VSQEAELRHRFRLEEAKSRDLKAEV 724
Score = 60.5 bits (140), Expect = 2e-08
Identities = 64/294 (21%), Positives = 146/294 (49%), Gaps = 27/294 (9%)
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K + K +L ++++ + + Q+ ++Q G+ +++Q LT ++ E E+ L+
Sbjct: 231 KRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLRE----EEEKLK--- 283
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA-------DE 465
++ + +E + ++ +L V + +S ++ +E+ A+ + ++LR+ E
Sbjct: 284 AITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIE 343
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ + L+ E L E +++I K E SL EV+N+ R+ E+E G I+
Sbjct: 344 ELEEINKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME-----GKDEEIT 398
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K E++ +++ +L EE+ E LR + +L++ + + E+ ++ S + E T
Sbjct: 399 KTESQCRELRKKLQEEEHHSKE----LRLEVEKLQKRMSELEKLEEAFS--KSKSECTQL 452
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+++ K + ++ +++ V + R +ELE +E R + AE +L K ++F
Sbjct: 453 HLNLEKEKNLTKDLLNELEVVKSR--VKELECSESRLEKAELSLKDDLTKLKSF 504
Score = 52.0 bits (119), Expect = 7e-06
Identities = 61/348 (17%), Positives = 153/348 (43%), Gaps = 16/348 (4%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ +L +++ +L+ +LN+ K E+E +R+ +AE LK ++T++K
Sbjct: 447 SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 506
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
+ + E + ++ + + K ++ ++ +++ + + L + ++
Sbjct: 507 MLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 566
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
+LT E +E+ G + + + + R++ + + ++ +++ EL
Sbjct: 567 NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELT---C 623
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
D KEL + ER ++ +L+ L + ++ ++E ++ + + +S +LEE
Sbjct: 624 PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 683
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+ K I+K +A I+ E+ E + RH ++ K R LK + +E
Sbjct: 684 I--------KHQIAKNKA-IEKGEVVSQEAELRHR--FRLEEAKSRDLKAEVQALKEKIH 732
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ +D L + S+ +++ E+E ++ V +ELE ++
Sbjct: 733 ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSK 780
Score = 39.9 bits (89), Expect = 0.028
Identities = 78/390 (20%), Positives = 162/390 (41%), Gaps = 20/390 (5%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+KR+ E+E + + K + ELR+K S + + +E+ ++ + +
Sbjct: 384 RKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE--VEKLQKRMSELEKLEEA 441
Query: 203 FQASRTLVNRDYTNLSKNV-LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
F S++ + + NL K L K L+ + SRV E R+ + + +
Sbjct: 442 FSKSKSECTQLHLNLEKEKNLTKDLLNE--LEVVKSRVKELECSESRLEKAELS--LKDD 497
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL-- 319
T+L + +++ + E +KQ ++ V LN + K ++ + +++E KL
Sbjct: 498 LTKLKSFTVMLVDERKNMMEKIKQ-EERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 556
Query: 320 -KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
KSE+ L + EL L + + +L ++ +L I+ E+ R
Sbjct: 557 LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSR 616
Query: 379 TLDQYGVAQ-RRIQSLTGEVEEIRGNYEQALRVKRSV---EQQYEESQ----TRVNELTV 430
+ + +I+ LT E+E ++ +Q V+ + E +Y++ + T ++
Sbjct: 617 KGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 676
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
++ L K +I + AI + ELR + +LK V+ L E+ ++
Sbjct: 677 LSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMN 736
Query: 491 IEAVKKSLEIEVKNISVR-LEEVEANAIVG 519
E L+++ + R +EE N +G
Sbjct: 737 KEDQLSQLQVDYSVLQQRFMEEENKNKNMG 766
>AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein.
Length = 247
Score = 60.9 bits (141), Expect = 1e-08
Identities = 45/230 (19%), Positives = 109/230 (47%), Gaps = 12/230 (5%)
Query: 323 VTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQ 382
+ +K+K+Q+ L+ D A + LQ+ ++ + + + + R++Q+ ++
Sbjct: 7 IEAVKRKIQV----LQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEE 62
Query: 383 YGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQY--EESQTRVNELTVINVNLSSSKA 440
AQ R+ + ++EE +++ R + +E + +E + + E+ + + +A
Sbjct: 63 LDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 122
Query: 441 -----KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
++ ++L I+ D + + +A+ + ++ ELK+ +L + + K +
Sbjct: 123 DRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKE 182
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRH 545
E E+K ++ +L+E E A +R ++KLE I D+E L + R+
Sbjct: 183 DKYEEEIKILTDKLKEAETRAEF-AERSVAKLEKTIDDLEERLYSQLERN 231
Score = 46.8 bits (106), Expect = 2e-04
Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 29/235 (12%)
Query: 367 THYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN 426
T + V+R++QV Q A+ R + L EVE R EQA + V Q
Sbjct: 5 TTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQA---EAEVASLNRRIQLVEE 61
Query: 427 ELTVINVNLSSSKAKIEQELAIVAADYDE----ITKELRIADERYQRVQTELKHTVEHLH 482
EL L+++ K+E+ A AAD E + + + DE +Q +H+
Sbjct: 62 ELDRAQERLATALQKLEE--AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIA 119
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDM-----ELE 537
EE +R K E V + L I I LE E A + + S+LE +K++ LE
Sbjct: 120 EEADR--KYEEVARKLVI----IEGDLERTEERAELAESK-CSELEEELKNVTNNLKSLE 172
Query: 538 LDEEK-----RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
EK ++ E IKIL K LKE + E +++++ L+ +++ +++
Sbjct: 173 AQAEKYSQKEDKYEEEIKILTDK---LKEAETRAEFAERSVAKLEKTIDDLEERL 224
Score = 42.7 bits (96), Expect = 0.004
Identities = 35/155 (22%), Positives = 79/155 (50%), Gaps = 15/155 (9%)
Query: 488 IVKIEAVKKSLEI---EVKNISVRLEEVEANAIVGGKRIISKLEARIKDME--LELDEEK 542
I IEAVK+ +++ + + R E ++ + G +R + EA + + ++L EE+
Sbjct: 4 ITTIEAVKRKIQVLQQQADDAEERAERLQRE-VEGERRAREQAEAEVASLNRRIQLVEEE 62
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
A+ + L ++L+E +E ++ + ++++ K +K+ + + QL E + +++
Sbjct: 63 LDRAQ--ERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 120
Query: 603 QSVTRVRRFQR-------ELEAAEDRADVAESNLS 630
++ + R +LE E+RA++AES S
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESKCS 155
Score = 36.7 bits (81), Expect = 0.26
Identities = 41/190 (21%), Positives = 83/190 (43%), Gaps = 15/190 (7%)
Query: 299 KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANK-TNIDLQKTIK- 356
+Q E+ LN R+ E +L R+ LQ ++ E E + D + + + + +K
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQ-KLEEAEKAADESERGMKVIENRALKD 101
Query: 357 KQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQ 416
++ ++L EIQ E + + +Y R++ + G++E E A +E+
Sbjct: 102 EEKMELQEIQLK--EAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEE 159
Query: 417 QYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADER---YQRVQTE 473
+ + + L S + K E+E+ I +T +L+ A+ R +R +
Sbjct: 160 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKI-------LTDKLKEAETRAEFAERSVAK 212
Query: 474 LKHTVEHLHE 483
L+ T++ L E
Sbjct: 213 LEKTIDDLEE 222
>AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens
cDNA FLJ43937 fis, clone TESTI4013924. ).
Length = 623
Score = 60.9 bits (141), Expect = 1e-08
Identities = 80/384 (20%), Positives = 175/384 (45%), Gaps = 35/384 (9%)
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITEL 337
E+K ++ L + S Q+ +++E+ + AE K KS+ K L++Q +
Sbjct: 216 EVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELK-KSQAQDKAKLLEMQESIK 274
Query: 338 ELSL---DVANKTNID--LQKTIKKQSLQLTEIQTHYDEVQRQLQVTLD-QYGVAQRRIQ 391
+LS D+ANK + +K + K LT DE + L + V QR ++
Sbjct: 275 DLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETATIITQLKLERDVHQRELK 334
Query: 392 SLTGEVEEIRGNYEQALR-VKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQ-ELAIV 449
LT ++ ++ +EQ ++ + + +++ E++ + L ++ + AKI + +L +
Sbjct: 335 DLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAESLE-EKNMAKIHRGQLEKL 393
Query: 450 AADYDEITKELRIADE-------RYQRVQTELKHTVEHLHEEQERIVKIEAVKKS----- 497
+ D +T+EL + +YQ ++ +L+ +H+ E+E + ++E +
Sbjct: 394 KSQCDRLTEELTQNENENKKLKLKYQCLKDQLEEREKHISIEEEHLRRMEEARLQLKDQL 453
Query: 498 --LEIEVKNI-SVRLEEVEANAIVGGKRIISKLEARIKDMELELD------EEKRR---H 545
LE E ++I V +E++A K + KL+ ++ D E K +
Sbjct: 454 LCLETEQESILGVIGKEIDAACKTFSKDSVEKLKVFSSGPDIHYDPHRWLAESKTKLQWL 513
Query: 546 AETIKILRKKERQLKEVIIQCEEDQKNISLLQDS-LEKTSQKVSIYKRQLAEQEGMSQQS 604
E +K +E+ L+ ++ C + +N++ ++S L+ Q++ ++ L E +
Sbjct: 514 CEELKERENREKNLRHQLMLCRQQLRNLTENKESELQCLFQQIERQEQLLDEIHREKRDL 573
Query: 605 VTRVRRFQRELEAAEDRADVAESN 628
+ +R E+ + +DR E++
Sbjct: 574 LEETQRKDEEMGSLQDRVIALETS 597
Score = 59.7 bits (138), Expect = 3e-08
Identities = 68/337 (20%), Positives = 159/337 (47%), Gaps = 30/337 (8%)
Query: 296 DSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
+ +T E+ N ++++ + +LK+++ + QI+ EL+ DV K + ++
Sbjct: 141 EKQSETVDELTGKNNQILKEKDELKTQLYAALQ--QIENLRKELN-DVLTKRALQEEELH 197
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQS---LTGEVEEIRGNYEQAL-RVK 411
K+ +L +I++H +++ +++ +LD + ++ + +++ + + E+ + +K
Sbjct: 198 SKEE-KLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELK 256
Query: 412 RSVEQQYE---ESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQ 468
+S Q E Q + +L+ I +L++ A+ E+ V D ++T + + DE
Sbjct: 257 KSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETA 316
Query: 469 RVQTELKHTVE-HLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
+ T+LK + H E ++ +++VK E ++ + ++ ++ A
Sbjct: 317 TIITQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEA----------- 365
Query: 528 EARIKDMELELDEEK---RRHAETIKILRKKERQLKEVIIQCEEDQKNISL----LQDSL 580
E I+ ++ E EEK + H ++ L+ + +L E + Q E + K + L L+D L
Sbjct: 366 ENHIRTLKAESLEEKNMAKIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQL 425
Query: 581 EKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEA 617
E+ + +SI + L E Q ++ + E E+
Sbjct: 426 EEREKHISIEEEHLRRMEEARLQLKDQLLCLETEQES 462
Score = 58.8 bits (136), Expect = 6e-08
Identities = 74/359 (20%), Positives = 165/359 (45%), Gaps = 40/359 (11%)
Query: 288 DLSVYILNDSSKQTSIE-IEQLNARVVEAETKLKSEVTRIKKKLQI----QITELELSLD 342
DL V LN S+ + +E +++ R + + L S+V + ++L+ Q+ L+ +
Sbjct: 3 DLRVQ-LNFSAMASELEEVKRCMERKDKEKAHLASQVENLTRELENGEKQQLQMLDRLKE 61
Query: 343 VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRG 402
+ N + + K LQ++E+ H ++ +Q + L + ++ + E+++
Sbjct: 62 IQNHFDT-CEAERKHADLQISELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKL 120
Query: 403 NYEQALRV----KRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITK 458
++++R + +E+ E+ V+ELT N + K +++ +L + + K
Sbjct: 121 KAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRK 180
Query: 459 ELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIV 518
EL D +R E E LH ++E++ I++ + LE+EVKN + +E+
Sbjct: 181 ELN--DVLTKRALQE-----EELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESEL-- 231
Query: 519 GGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQD 578
+ SK+++++K + L+EE I L+K + Q K +++ +E K++S ++
Sbjct: 232 ---KKQSKIQSQMKVEKAHLEEE-------IAELKKSQAQDKAKLLEMQESIKDLSAIRA 281
Query: 579 SLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
L +LAE+E + + + + ++ ++ + L L R H+
Sbjct: 282 DLAN----------KLAEEERAKKAVLKDLSDLTAQAKSRDEETATIITQLKLERDVHQ 330
Score = 58.0 bits (134), Expect = 1e-07
Identities = 80/406 (19%), Positives = 184/406 (45%), Gaps = 38/406 (9%)
Query: 258 VVRINTELPAIDNSYLNQLNELKETVKQFD---------DLSVYILNDSSKQTSIEIEQL 308
V + EL + L L+ LKE FD DL + L ++ + + E+
Sbjct: 38 VENLTRELENGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERY 97
Query: 309 NARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTH 368
+ + ++E LK E + ++ L+++ E + +K L++ ++KQS + E+
Sbjct: 98 LSELQQSEA-LKEEAEKRREDLKLKAQESIRQWKLKHKK---LERALEKQSETVDELTGK 153
Query: 369 YDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEI---RGNYEQALRVK----RSVEQQYEES 421
+++ ++ Q A ++I++L E+ ++ R E+ L K R ++ +
Sbjct: 154 NNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKLRDIKSHQADL 213
Query: 422 QTRV-NELTVINVNLSSSK--AKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTV 478
+ V N L I+ S K +KI+ ++ + A +E EL+ + + + E++ ++
Sbjct: 214 ELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQESI 273
Query: 479 EHLH----EEQERIVKIEAVKKSLEIEVKNISVRLE--EVEANAIVGGKRIISKLEAR-I 531
+ L + ++ + E KK++ ++ +++ + + + E I+ ++ + R +
Sbjct: 274 KDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETATIITQLKLERDVHQREL 333
Query: 532 KDMELELDEEKRRHAETIKILRK---KERQLKEVIIQCEE----DQKNISLL-QDSLEKT 583
KD+ L K +H + I+ L K KE+ E I+ + ++KN++ + + LEK
Sbjct: 334 KDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAESLEEKNMAKIHRGQLEKL 393
Query: 584 SQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+ +L + E +++ + + + +LE E + E +L
Sbjct: 394 KSQCDRLTEELTQNENENKKLKLKYQCLKDQLEEREKHISIEEEHL 439
Score = 57.2 bits (132), Expect = 2e-07
Identities = 75/349 (21%), Positives = 160/349 (45%), Gaps = 45/349 (12%)
Query: 319 LKSEVTRIKKKLQIQITE-LELSLDVANKTNIDLQKTIKKQSLQ----LTEIQTHYDEVQ 373
+ SE+ +K+ ++ + E L+ V N T +L+ +KQ LQ L EIQ H+D +
Sbjct: 13 MASELEEVKRCMERKDKEKAHLASQVENLTR-ELENG-EKQQLQMLDRLKEIQNHFDTCE 70
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEE----SQTRVNELT 429
+ + Q R + T + E +Q+ +K E++ E+ +Q + +
Sbjct: 71 AERKHADLQISELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQWK 130
Query: 430 VINVNLSSSKAKIEQ---ELA----IVAADYDEITKELRIADERYQRVQTELKHTV---- 478
+ + L + K + EL + + DE+ +L A ++ + ++ EL +
Sbjct: 131 LKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRA 190
Query: 479 ---EHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E LH ++E++ I++ + LE+EVKN + +E+ + SK+++++K +
Sbjct: 191 LQEEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESEL-----KKQSKIQSQMKVEK 245
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSL-----EKTSQKVSIY 590
L+EE I L+K + Q K +++ +E K++S ++ L E+ K ++
Sbjct: 246 AHLEEE-------IAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVL 298
Query: 591 K---RQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKH 636
K A+ + +++ T + + + E + + S+L ++ KH
Sbjct: 299 KDLSDLTAQAKSRDEETATIITQLKLERDVHQRELKDLTSSLQSVKTKH 347
>BC009941-1|AAH09941.1| 550|Homo sapiens coiled-coil domain
containing 102A protein.
Length = 550
Score = 60.5 bits (140), Expect = 2e-08
Identities = 52/282 (18%), Positives = 125/282 (44%), Gaps = 17/282 (6%)
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
++++ +LT ++ DE Q+ L + R I+ L GE+ + + YE+ + K+ +
Sbjct: 246 EEEASKLTALRLRLDESQKVLLKEREDKLALSRNIEKLEGELSQWKIKYEELSKTKQEML 305
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
+Q LS K + EL ++ D ++ D + ++ E++
Sbjct: 306 KQ-----------------LSILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEME 348
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E R ++E K LE E K + ++ ++E ++ S L+ ++ +
Sbjct: 349 RLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQTASALDCDLRASQ 408
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
L E+ + A+ + K ++Q +E + + + + + ++K +V K++LA
Sbjct: 409 AALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHEAEVKKLRLRVEELKKELA 468
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ E ++ + R+ QR L+ ++++ + L ++++ R
Sbjct: 469 QAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLR 510
>BC008285-1|AAH08285.1| 550|Homo sapiens coiled-coil domain
containing 102A protein.
Length = 550
Score = 60.5 bits (140), Expect = 2e-08
Identities = 52/282 (18%), Positives = 125/282 (44%), Gaps = 17/282 (6%)
Query: 356 KKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE 415
++++ +LT ++ DE Q+ L + R I+ L GE+ + + YE+ + K+ +
Sbjct: 246 EEEASKLTALRLRLDESQKVLLKEREDKLALSRNIEKLEGELSQWKIKYEELSKTKQEML 305
Query: 416 QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELK 475
+Q LS K + EL ++ D ++ D + ++ E++
Sbjct: 306 KQ-----------------LSILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEME 348
Query: 476 HTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDME 535
E R ++E K LE E K + ++ ++E ++ S L+ ++ +
Sbjct: 349 RLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQTASALDCDLRASQ 408
Query: 536 LELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLA 595
L E+ + A+ + K ++Q +E + + + + + ++K +V K++LA
Sbjct: 409 AALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHEAEVKKLRLRVEELKKELA 468
Query: 596 EQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHR 637
+ E ++ + R+ QR L+ ++++ + L ++++ R
Sbjct: 469 QAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLR 510
>M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antigen
protein.
Length = 2095
Score = 60.1 bits (139), Expect = 2e-08
Identities = 74/397 (18%), Positives = 182/397 (45%), Gaps = 22/397 (5%)
Query: 256 TCVVRINTELPAIDNSYLNQLNELK-ETVKQFDDLSVYI-LNDSSKQTSIEIEQLNARVV 313
T +V + T+ L +L E + + K+ + Y L K T +E +L ++
Sbjct: 528 TALVTLMTQYIKFAGDSLKRLEEEEIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKIS 587
Query: 314 EAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
E E ++ +E+ + K +++ ++ ++ + A Q+ ++ SLQ ++ + +
Sbjct: 588 ELE-RMVAELKKQKSRVEEELPKVR---EAAENELRKQQRNVEDISLQKIRAESEAKQYR 643
Query: 374 RQLQVTLDQYGVAQR---RIQSLTGEVEEIRGNYEQ-ALRVKRSVEQQYEESQTRVNELT 429
R+L+ + + A+R R++ LT E E R E+ L + +E+ +T + L
Sbjct: 644 RELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLK 703
Query: 430 VINVNLSS---SKAKIEQELAIVAADYDEITKELRIADE----RYQRVQTELKHTVEHLH 482
+++L+ K K+ +EL + +E+ K ++ ++ + Q + +LK +
Sbjct: 704 RKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIEL 763
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E + +I +I+ + + V I+ + A+ G ++ K +A ++++ ++DE
Sbjct: 764 EARRKITEIQYTCRENALPVCPIT---QATSCRAVTGLQQEHDKQKA--EELKQQVDELT 818
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ + + +R+ +L + ++ ++ LL+D L++T+ + K +L ++ +
Sbjct: 819 AANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEK 878
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
++R R+L +A+ A S ++ R +
Sbjct: 879 GYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNY 915
Score = 50.0 bits (114), Expect = 3e-05
Identities = 68/391 (17%), Positives = 161/391 (41%), Gaps = 15/391 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
+LN L + K + +L D +T+ + L + E + + + ++ ++L Q+
Sbjct: 834 ELNAL-QLEKTSSEEKARLLKDKLDETNNTLRCLKLEL-ERKDQAEKGYSQQLRELGRQL 891
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
+ + A + DL+K + L+L + ++QR++ + VA++ IQ L
Sbjct: 892 NQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLN 951
Query: 395 GEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++ R E + L++ + +E + +E + N+ Q L
Sbjct: 952 SQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKS 1011
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIV----KIEAVKKSLEIEVKNISVRL 509
+E + L+ E R E K ++ + E E IV I+ ++L+I+ +L
Sbjct: 1012 NECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQL 1071
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
+ + + + +IK +E +L + + +E K++ + +IIQ
Sbjct: 1072 RSTNEH-LHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEF-----KQKCDQQNIIIQ--NT 1123
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+K + L L + ++ ++++ Q+ Q+ R+++ Q EL + +
Sbjct: 1124 KKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKM 1183
Query: 630 SLIRAKHRTFVTTSTVPGSQVYLVQESRALS 660
L + + F ++ ++ + ES+ ++
Sbjct: 1184 VLFQEESGKFKQSAEEFRKKMEKLMESKVIT 1214
Score = 35.5 bits (78), Expect = 0.61
Identities = 91/511 (17%), Positives = 198/511 (38%), Gaps = 57/511 (11%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAA----MYRGKSAKAIAQTLLEESRRNVQNER 197
+K+++E +K EL+ K + R+ A + + S +A+ E ++ + +
Sbjct: 752 EKQLKEKQKIELEARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELK 811
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
+ A+ +D L+ + AL K + +R+ + ++ ET+ T
Sbjct: 812 QQVDELTAANRKAEQDMRELTYEL--NALQLEKTSSEEKARLLKD-----KLDETNNTLR 864
Query: 258 VVRINTELP-AIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE-QLNARVVEA 315
+++ E + Y QL EL + Q + + ++S I+ QL +
Sbjct: 865 CLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNH 924
Query: 316 ET-KLKSEVTRIKKKLQIQITELE-LSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
E KL+ EV RI + + ++ L+ + + + + ++ + ++ +++
Sbjct: 925 EKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSH 984
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
QL + +IQ L E+E+ E + + +Q E++ + + +
Sbjct: 985 EQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESE 1044
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERY-------QRVQTELKHTVEHLHEEQE 486
N+ K I+Q + D +LR +E Q Q ++K E L + Q
Sbjct: 1045 NIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQN 1104
Query: 487 RIVKIEA-------VKKSLEIEVKNISVRLEEVEANAIVGGKRI------ISKLEARIKD 533
+ + + + ++ + EV+N++ L + G +++ + +L R+K
Sbjct: 1105 LVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKK 1164
Query: 534 MELEL-----------------DEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL- 575
++ EL EE + ++ + RKK +L E + E D I L
Sbjct: 1165 VQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLD 1224
Query: 576 ---LQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
LQ + + + + + E E QQ
Sbjct: 1225 FVSLQQENSRAQENAKLCETNIKELERQLQQ 1255
>L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antigen
protein.
Length = 2649
Score = 60.1 bits (139), Expect = 2e-08
Identities = 74/397 (18%), Positives = 182/397 (45%), Gaps = 22/397 (5%)
Query: 256 TCVVRINTELPAIDNSYLNQLNELK-ETVKQFDDLSVYI-LNDSSKQTSIEIEQLNARVV 313
T +V + T+ L +L E + + K+ + Y L K T +E +L ++
Sbjct: 1082 TALVTLMTQYIKFAGDSLKRLEEEEIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKIS 1141
Query: 314 EAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
E E ++ +E+ + K +++ ++ ++ + A Q+ ++ SLQ ++ + +
Sbjct: 1142 ELE-RMVAELKKQKSRVEEELPKVR---EAAENELRKQQRNVEDISLQKIRAESEAKQYR 1197
Query: 374 RQLQVTLDQYGVAQR---RIQSLTGEVEEIRGNYEQ-ALRVKRSVEQQYEESQTRVNELT 429
R+L+ + + A+R R++ LT E E R E+ L + +E+ +T + L
Sbjct: 1198 RELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLK 1257
Query: 430 VINVNLSS---SKAKIEQELAIVAADYDEITKELRIADE----RYQRVQTELKHTVEHLH 482
+++L+ K K+ +EL + +E+ K ++ ++ + Q + +LK +
Sbjct: 1258 RKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIEL 1317
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E + +I +I+ + + V I+ + A+ G ++ K +A ++++ ++DE
Sbjct: 1318 EARRKITEIQYTCRENALPVCPIT---QATSCRAVTGLQQEHDKQKA--EELKQQVDELT 1372
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ + + +R+ +L + ++ ++ LL+D L++T+ + K +L ++ +
Sbjct: 1373 AANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEK 1432
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
++R R+L +A+ A S ++ R +
Sbjct: 1433 GYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNY 1469
Score = 50.0 bits (114), Expect = 3e-05
Identities = 68/391 (17%), Positives = 161/391 (41%), Gaps = 15/391 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
+LN L + K + +L D +T+ + L + E + + + ++ ++L Q+
Sbjct: 1388 ELNAL-QLEKTSSEEKARLLKDKLDETNNTLRCLKLEL-ERKDQAEKGYSQQLRELGRQL 1445
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
+ + A + DL+K + L+L + ++QR++ + VA++ IQ L
Sbjct: 1446 NQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLN 1505
Query: 395 GEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++ R E + L++ + +E + +E + N+ Q L
Sbjct: 1506 SQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKS 1565
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIV----KIEAVKKSLEIEVKNISVRL 509
+E + L+ E R E K ++ + E E IV I+ ++L+I+ +L
Sbjct: 1566 NECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQL 1625
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
+ + + + +IK +E +L + + +E K++ + +IIQ
Sbjct: 1626 RSTNEH-LHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEF-----KQKCDQQNIIIQ--NT 1677
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+K + L L + ++ ++++ Q+ Q+ R+++ Q EL + +
Sbjct: 1678 KKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKM 1737
Query: 630 SLIRAKHRTFVTTSTVPGSQVYLVQESRALS 660
L + + F ++ ++ + ES+ ++
Sbjct: 1738 VLFQEESGKFKQSAEEFRKKMEKLMESKVIT 1768
Score = 35.5 bits (78), Expect = 0.61
Identities = 91/511 (17%), Positives = 198/511 (38%), Gaps = 57/511 (11%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAA----MYRGKSAKAIAQTLLEESRRNVQNER 197
+K+++E +K EL+ K + R+ A + + S +A+ E ++ + +
Sbjct: 1306 EKQLKEKQKIELEARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELK 1365
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
+ A+ +D L+ + AL K + +R+ + ++ ET+ T
Sbjct: 1366 QQVDELTAANRKAEQDMRELTYEL--NALQLEKTSSEEKARLLKD-----KLDETNNTLR 1418
Query: 258 VVRINTELP-AIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE-QLNARVVEA 315
+++ E + Y QL EL + Q + + ++S I+ QL +
Sbjct: 1419 CLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNH 1478
Query: 316 ET-KLKSEVTRIKKKLQIQITELE-LSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
E KL+ EV RI + + ++ L+ + + + + ++ + ++ +++
Sbjct: 1479 EKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSH 1538
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
QL + +IQ L E+E+ E + + +Q E++ + + +
Sbjct: 1539 EQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESE 1598
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERY-------QRVQTELKHTVEHLHEEQE 486
N+ K I+Q + D +LR +E Q Q ++K E L + Q
Sbjct: 1599 NIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQN 1658
Query: 487 RIVKIEA-------VKKSLEIEVKNISVRLEEVEANAIVGGKRI------ISKLEARIKD 533
+ + + + ++ + EV+N++ L + G +++ + +L R+K
Sbjct: 1659 LVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKK 1718
Query: 534 MELEL-----------------DEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL- 575
++ EL EE + ++ + RKK +L E + E D I L
Sbjct: 1719 VQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLD 1778
Query: 576 ---LQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
LQ + + + + + E E QQ
Sbjct: 1779 FVSLQQENSRAQENAKLCETNIKELERQLQQ 1809
>AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein.
Length = 2649
Score = 60.1 bits (139), Expect = 2e-08
Identities = 74/397 (18%), Positives = 182/397 (45%), Gaps = 22/397 (5%)
Query: 256 TCVVRINTELPAIDNSYLNQLNELK-ETVKQFDDLSVYI-LNDSSKQTSIEIEQLNARVV 313
T +V + T+ L +L E + + K+ + Y L K T +E +L ++
Sbjct: 1082 TALVTLMTQYIKFAGDSLKRLEEEEIKRCKETSEHGAYSDLLQRQKATVLENSKLTGKIS 1141
Query: 314 EAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
E E ++ +E+ + K +++ ++ ++ + A Q+ ++ SLQ ++ + +
Sbjct: 1142 ELE-RMVAELKKQKSRVEEELPKVR---EAAENELRKQQRNVEDISLQKIRAESEAKQYR 1197
Query: 374 RQLQVTLDQYGVAQR---RIQSLTGEVEEIRGNYEQ-ALRVKRSVEQQYEESQTRVNELT 429
R+L+ + + A+R R++ LT E E R E+ L + +E+ +T + L
Sbjct: 1198 RELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLK 1257
Query: 430 VINVNLSS---SKAKIEQELAIVAADYDEITKELRIADE----RYQRVQTELKHTVEHLH 482
+++L+ K K+ +EL + +E+ K ++ ++ + Q + +LK +
Sbjct: 1258 RKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIEL 1317
Query: 483 EEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEK 542
E + +I +I+ + + V I+ + A+ G ++ K +A ++++ ++DE
Sbjct: 1318 EARRKITEIQYTCRENALPVCPIT---QATSCRAVTGLQQEHDKQKA--EELKQQVDELT 1372
Query: 543 RRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQ 602
+ + + +R+ +L + ++ ++ LL+D L++T+ + K +L ++ +
Sbjct: 1373 AANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEK 1432
Query: 603 QSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
++R R+L +A+ A S ++ R +
Sbjct: 1433 GYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNY 1469
Score = 50.0 bits (114), Expect = 3e-05
Identities = 68/391 (17%), Positives = 161/391 (41%), Gaps = 15/391 (3%)
Query: 275 QLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQI 334
+LN L + K + +L D +T+ + L + E + + + ++ ++L Q+
Sbjct: 1388 ELNAL-QLEKTSSEEKARLLKDKLDETNNTLRCLKLEL-ERKDQAEKGYSQQLRELGRQL 1445
Query: 335 TELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLT 394
+ + A + DL+K + L+L + ++QR++ + VA++ IQ L
Sbjct: 1446 NQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLN 1505
Query: 395 GEVEEIRGNYE-QALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADY 453
++ R E + L++ + +E + +E + N+ Q L
Sbjct: 1506 SQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKS 1565
Query: 454 DEITKELRIADERYQRVQTELKHTVEHLHEEQERIV----KIEAVKKSLEIEVKNISVRL 509
+E + L+ E R E K ++ + E E IV I+ ++L+I+ +L
Sbjct: 1566 NECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQL 1625
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
+ + + + +IK +E +L + + +E K++ + +IIQ
Sbjct: 1626 RSTNEH-LHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEF-----KQKCDQQNIIIQ--NT 1677
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNL 629
+K + L L + ++ ++++ Q+ Q+ R+++ Q EL + +
Sbjct: 1678 KKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKM 1737
Query: 630 SLIRAKHRTFVTTSTVPGSQVYLVQESRALS 660
L + + F ++ ++ + ES+ ++
Sbjct: 1738 VLFQEESGKFKQSAEEFRKKMEKLMESKVIT 1768
Score = 35.5 bits (78), Expect = 0.61
Identities = 91/511 (17%), Positives = 198/511 (38%), Gaps = 57/511 (11%)
Query: 143 KKRMQEIEK-ELDLYEKEVNLGSELRQKAA----MYRGKSAKAIAQTLLEESRRNVQNER 197
+K+++E +K EL+ K + R+ A + + S +A+ E ++ + +
Sbjct: 1306 EKQLKEKQKIELEARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELK 1365
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTC 257
+ A+ +D L+ + AL K + +R+ + ++ ET+ T
Sbjct: 1366 QQVDELTAANRKAEQDMRELTYEL--NALQLEKTSSEEKARLLKD-----KLDETNNTLR 1418
Query: 258 VVRINTELP-AIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIE-QLNARVVEA 315
+++ E + Y QL EL + Q + + ++S I+ QL +
Sbjct: 1419 CLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNH 1478
Query: 316 ET-KLKSEVTRIKKKLQIQITELE-LSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQ 373
E KL+ EV RI + + ++ L+ + + + + ++ + ++ +++
Sbjct: 1479 EKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSH 1538
Query: 374 RQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINV 433
QL + +IQ L E+E+ E + + +Q E++ + + +
Sbjct: 1539 EQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESE 1598
Query: 434 NLSSSKAKIEQELAIVAADYDEITKELRIADERY-------QRVQTELKHTVEHLHEEQE 486
N+ K I+Q + D +LR +E Q Q ++K E L + Q
Sbjct: 1599 NIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQN 1658
Query: 487 RIVKIEA-------VKKSLEIEVKNISVRLEEVEANAIVGGKRI------ISKLEARIKD 533
+ + + + ++ + EV+N++ L + G +++ + +L R+K
Sbjct: 1659 LVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKK 1718
Query: 534 MELEL-----------------DEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL- 575
++ EL EE + ++ + RKK +L E + E D I L
Sbjct: 1719 VQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLD 1778
Query: 576 ---LQDSLEKTSQKVSIYKRQLAEQEGMSQQ 603
LQ + + + + + E E QQ
Sbjct: 1779 FVSLQQENSRAQENAKLCETNIKELERQLQQ 1809
>AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens
cDNA FLJ13323 fis, clone OVARC1001731, highly similar to
TROPOMYOSIN ALPHA CHAIN, FIBROBLAST ISOFORM F2. ).
Length = 284
Score = 60.1 bits (139), Expect = 2e-08
Identities = 57/258 (22%), Positives = 121/258 (46%), Gaps = 16/258 (6%)
Query: 299 KQTSIE-IEQLNARVVEAETKLKS---EVTRIKKKLQIQITELELSLDVANKTNIDLQKT 354
K+ +I+ EQ A AE K K E+T ++KKL+ EL+ + L+ T
Sbjct: 15 KENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELT 74
Query: 355 IKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSV 414
KK S + + + R++Q+ ++ AQ R+ + ++EE +++ R + +
Sbjct: 75 EKKAS----DAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 130
Query: 415 EQQY--EESQTRVNELTVINVNLSSSKA-----KIEQELAIVAADYDEITKELRIADERY 467
E + +E + + E+ + + +A ++ ++L I+ + + + +++ +
Sbjct: 131 ENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKC 190
Query: 468 QRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKL 527
++ ELK+ +L + K + E E+K +S +L+E E A +R ++KL
Sbjct: 191 GDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEF-AERTVAKL 249
Query: 528 EARIKDMELELDEEKRRH 545
E I D+E +L + K +
Sbjct: 250 EKTIDDLEEKLAQAKEEN 267
Score = 52.8 bits (121), Expect = 4e-06
Identities = 47/193 (24%), Positives = 97/193 (50%), Gaps = 24/193 (12%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEI 500
K+++E AI A+ E K + A+++ ++V+ EL H + L ++ + K
Sbjct: 12 KLDKENAIDRAEQAEADK--KAAEDKCKQVEEELTHLQKKLKGTEDELDKYSE------- 62
Query: 501 EVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLK 560
++K+ +LE E A + ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 63 DLKDAQEKLELTEKKAS-DAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKA-- 119
Query: 561 EVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------- 613
+E ++ + ++++ K +K+ I + QL E + +++++ + R
Sbjct: 120 -----ADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEG 174
Query: 614 ELEAAEDRADVAE 626
ELE AE+RA+V+E
Sbjct: 175 ELERAEERAEVSE 187
Score = 37.1 bits (82), Expect = 0.20
Identities = 55/261 (21%), Positives = 114/261 (43%), Gaps = 35/261 (13%)
Query: 387 QRRIQSLTGEVEEIRGNYEQALRVKRSVE---QQYEESQTRV--------NELTVINVNL 435
++++Q L + E EQA K++ E +Q EE T + +EL + +L
Sbjct: 5 KKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKYSEDL 64
Query: 436 SSSKAKIE---QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIE 492
++ K+E ++ + D + + +++ +E R Q L ++ L E ++ + E
Sbjct: 65 KDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124
Query: 493 AVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELEL---DEEKRRHAETI 549
K +E ++E ++ + K I + + + +++ +L + E R E
Sbjct: 125 RGMKVIENRAMKDEEKME-IQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERA 183
Query: 550 KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
++ K L EE+ KN++ SLE S+K S E+E ++ ++
Sbjct: 184 EVSELKCGDL-------EEELKNVTNNLKSLEAASEKYS-------EKEDKYEE---EIK 226
Query: 610 RFQRELEAAEDRADVAESNLS 630
+L+ AE RA+ AE ++
Sbjct: 227 LLSDKLKEAETRAEFAERTVA 247
Score = 31.5 bits (68), Expect = 9.9
Identities = 28/107 (26%), Positives = 51/107 (47%), Gaps = 3/107 (2%)
Query: 527 LEARIKDME-LELDEEKR-RHAETIKILRKK-ERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+EA K M+ L+LD+E AE + +K E + K+V + QK + +D L+K
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 584 SQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLS 630
S+ + + +L E + + V R ++ E+ D A+ L+
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLA 107
Score = 31.5 bits (68), Expect = 9.9
Identities = 51/229 (22%), Positives = 95/229 (41%), Gaps = 17/229 (7%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSE----LRQKAAMYRGKSAKAIAQTLLEESRRNVQNERM 198
+K+++ E ELD Y +++ E +KA+ G A + L E + ER+
Sbjct: 47 QKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERL 106
Query: 199 YKPDFQASRTLVNRDYTNLSKNVLA-KALMESKAMNSCDSRVTES--ITETVRVRETSPT 255
+ D + V+ +A+ + + M + ++ E+ I E +
Sbjct: 107 ATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVA 166
Query: 256 TCVVRINTELP-AIDNSYLNQLN------ELKETVKQFDDLSVYILNDSSKQTSIE--IE 306
+V + EL A + + +++L ELK L S K+ E I+
Sbjct: 167 RKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIK 226
Query: 307 QLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI 355
L+ ++ EAET+ + R KL+ I +LE L A + N+ L +T+
Sbjct: 227 LLSDKLKEAETRAEF-AERTVAKLEKTIDDLEEKLAQAKEENVGLHQTL 274
>AB046860-1|BAB13466.1| 940|Homo sapiens KIAA1640 protein protein.
Length = 940
Score = 60.1 bits (139), Expect = 2e-08
Identities = 74/370 (20%), Positives = 159/370 (42%), Gaps = 16/370 (4%)
Query: 297 SSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ---IQITELELSLDVANKTNIDLQK 353
+S +T+ QL R+ + +T + + +++I + + IT LD KT ++L +
Sbjct: 439 TSNKTTKYFNQLILRLQKEKTNMMTHLSKINGDIAQTTLDITHTSSRLDAHQKTLVELDQ 498
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVK-R 412
+KK + +T Q+ E+ R+ + + G+ + L V E+ G L ++ +
Sbjct: 499 DVKKVNELITNSQS---EISRRTILIERKQGLINFLNKQLERMVSELGGEEVGPLELEIK 555
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQT 472
+ + +E + + V + L K+ QE A D KEL I +++ RV++
Sbjct: 556 RLSKLIDEHDGKAVQAQVTWLRLQQEMVKVTQEQEEQLASLDASKKELHIMEQKKLRVES 615
Query: 473 ELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIK 532
+++ + E + + ++ K L + + EE+E N V + L+A +
Sbjct: 616 KIEQEKKEQKEIEHHMKDLDNDLKKLNMLMNKNRCSSEELEQNNRVTENEFVRSLKASER 675
Query: 533 D---MELELDEEKRRHAETIKILRKKERQ--LKEVIIQCEEDQKNISLLQDSLEKTSQKV 587
+ M+ +L++ A + L + E Q L E IQ ++ + S + + +T ++
Sbjct: 676 ETIKMQDKLNQLSEEKATLLNQLVEAEHQIMLWEKKIQLAKEMR--SSVDSEIGQT--EI 731
Query: 588 SIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPG 647
K ++ + Q + + + R +E A R + + R R +T +
Sbjct: 732 RAMKGEIHRMKVRLGQLLKQQEKMIRAMELAVARRETVTTQAEGQRKMDRKALTRTDFHH 791
Query: 648 SQVYLVQESR 657
Q+ L ++ R
Sbjct: 792 KQLELRRKIR 801
Score = 56.8 bits (131), Expect = 2e-07
Identities = 85/452 (18%), Positives = 209/452 (46%), Gaps = 37/452 (8%)
Query: 147 QEIEKELDLYEK-EVNLGSELRQKAAMYRGKSAKAIAQTLLE-ESRRNVQNERMYKPDFQ 204
Q I+ EL+L K + + +L++ M K+ K Q +L + + + K +
Sbjct: 414 QAIQGELELRRKTDAAIREKLQEH--MTSNKTTKYFNQLILRLQKEKTNMMTHLSKINGD 471
Query: 205 ASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTE 264
++T ++ +T+ + K L+E ++ +V E IT + E S T ++
Sbjct: 472 IAQTTLDITHTSSRLDAHQKTLVE---LDQDVKKVNELITNSQS--EISRRTILIERKQG 526
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAET---KLKS 321
L ++LN+ +L+ V + V L K+ S I++ + + V+A+ +L+
Sbjct: 527 LI----NFLNK--QLERMVSELGGEEVGPLELEIKRLSKLIDEHDGKAVQAQVTWLRLQQ 580
Query: 322 EVTRIKKKLQIQITELELS---LDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
E+ ++ ++ + Q+ L+ S L + + + ++ I+++ + EI+ H ++ L+
Sbjct: 581 EMVKVTQEQEEQLASLDASKKELHIMEQKKLRVESKIEQEKKEQKEIEHHMKDLDNDLK- 639
Query: 379 TLDQYGVAQRRIQSLTGEVEEI-RGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSS 437
+ + + + + E+E+ R + +R ++ E++ + Q ++N+L+ L +
Sbjct: 640 ---KLNMLMNKNRCSSEELEQNNRVTENEFVRSLKASERETIKMQDKLNQLSEEKATLLN 696
Query: 438 SKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKS 497
+ E ++ + ++ KE+R + + + QTE++ +H + R+ ++ ++
Sbjct: 697 QLVEAEHQIMLWEKKI-QLAKEMRSSVDS-EIGQTEIRAMKGEIHRMKVRLGQLLKQQEK 754
Query: 498 LEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKER 557
+ I ++V E G +++ K R +L+ ++ I+ +RK
Sbjct: 755 M-IRAMELAVARRETVTTQAEGQRKMDRKALTRTDFHHKQLELRRK-----IRDVRKATD 808
Query: 558 QLKEVIIQCEEDQKNISLLQDSLEKTSQKVSI 589
+ + +++ EE Q+N+S SL + +K+S+
Sbjct: 809 ECTKTVLELEETQRNVS---SSLLEKQEKLSV 837
Score = 44.8 bits (101), Expect = 0.001
Identities = 54/247 (21%), Positives = 113/247 (45%), Gaps = 13/247 (5%)
Query: 269 DNSYLNQLNEL-KETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLK-SEVTRI 326
+N ++ L +ET+K D L+ L++ ++ + +++ E K++ ++ R
Sbjct: 663 ENEFVRSLKASERETIKMQDKLNQ--LSEEKATLLNQLVEAEHQIMLWEKKIQLAKEMRS 720
Query: 327 KKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVA 386
+I TE+ ++ + L + +K+Q + ++ V R+ VT G
Sbjct: 721 SVDSEIGQTEIRAMKGEIHRMKVRLGQLLKQQEKMIRAMEL---AVARRETVTTQAEG-- 775
Query: 387 QRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQEL 446
QR++ + + R R V + +E V EL N+SSS + +++L
Sbjct: 776 QRKMDRKALTRTDFHHKQLELRRKIRDVRKATDECTKTVLELEETQRNVSSSLLEKQEKL 835
Query: 447 AIVAADYDEITKEL-RIADERYQRVQ--TELKHTVEHLHEEQE-RIVKIEAVKKSLEIEV 502
+++ AD+D + +L R+ + Q + L+ ++HL +E R V + K+SL +E
Sbjct: 836 SVIQADFDTLEADLTRLGALKRQNLSEIVALQTRLKHLQAVKEGRYVFLFRSKQSLVLER 895
Query: 503 KNISVRL 509
+ + RL
Sbjct: 896 QRLDKRL 902
>X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for
skeletal beta-tropomyosin. ).
Length = 284
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/255 (19%), Positives = 123/255 (48%), Gaps = 10/255 (3%)
Query: 299 KQTSIE-IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKK 357
K+ +I+ EQ A +AE + K ++ ++ LQ ++ E ++ +++ + Q+ +++
Sbjct: 15 KENAIDRAEQAEADKKQAEDRCK-QLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQ 73
Query: 358 QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE-- 415
+ T+ + + R++Q+ ++ AQ R+ + ++EE +++ R + +E
Sbjct: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR 133
Query: 416 -----QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
++ E + ++ E I + ++ ++L I+ + + + +A+ + +
Sbjct: 134 AMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDL 193
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
+ ELK +L + + K + E E+K + +L+E E A +R ++KLE
Sbjct: 194 EEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEF-AERSVAKLEKT 252
Query: 531 IKDMELELDEEKRRH 545
I D+E E+ +K ++
Sbjct: 253 IDDLEDEVYAQKMKY 267
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/195 (25%), Positives = 100/195 (51%), Gaps = 26/195 (13%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI-EAVKKSLE 499
K+++E AI A+ E K+ A++R ++++ E + + L ++ + K E+VK++ E
Sbjct: 12 KLDKENAIDRAEQAEADKKQ--AEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQE 69
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+LE+ E A + ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 70 --------KLEQAEKKA-TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA- 119
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------ 613
+E ++ + ++++ K +K+ + + QL E + +++ S + R
Sbjct: 120 ------ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 173
Query: 614 -ELEAAEDRADVAES 627
ELE +E+RA+VAES
Sbjct: 174 GELERSEERAEVAES 188
>D86326-1|BAA25300.1| 962|Homo sapiens p115 protein.
Length = 962
Score = 59.7 bits (138), Expect = 3e-08
Identities = 70/327 (21%), Positives = 146/327 (44%), Gaps = 15/327 (4%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+E + VK+ + + + SS++ E E + +E + + + ++ +Q+ E
Sbjct: 611 HEFTKLVKELEGVITKAIYKSSEEDKKEEEV--KKTLEQHDNIVTHYKNMIREQDLQLEE 668
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
L + N LQ + +Q Q+ + + Y+ ++ QL G Q +
Sbjct: 669 LRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQ 728
Query: 397 VEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEI 456
EEI E+ +KR+ Q+ +SQ + + N+ S + EQ AIV+A E
Sbjct: 729 PEEIGRLREEIEELKRN--QELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQ 786
Query: 457 TKELR--IADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKN---ISVRLEE 511
EL+ +A + Q + ++ + E+QE + K EA KS+E++ + I+ + +
Sbjct: 787 VAELKQELATLKSQ-LNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTD 845
Query: 512 VEA--NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
VE +A++ + + + + + E+ TI IL+ ++ +L+ I +++
Sbjct: 846 VEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKE 905
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAE 596
Q ++ +L L QK+ K +L +
Sbjct: 906 QDDLLVL---LADQDQKILSLKNKLKD 929
>BC032654-1|AAH32654.1| 961|Homo sapiens vesicle docking protein
p115 protein.
Length = 961
Score = 59.7 bits (138), Expect = 3e-08
Identities = 70/327 (21%), Positives = 146/327 (44%), Gaps = 15/327 (4%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+E + VK+ + + + SS++ E E + +E + + + ++ +Q+ E
Sbjct: 610 HEFTKLVKELEGVITKAIYKSSEEDKKEEEV--KKTLEQHDNIVTHYKNMIREQDLQLEE 667
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
L + N LQ + +Q Q+ + + Y+ ++ QL G Q +
Sbjct: 668 LRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQ 727
Query: 397 VEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEI 456
EEI E+ +KR+ Q+ +SQ + + N+ S + EQ AIV+A E
Sbjct: 728 PEEIGRLREEIEELKRN--QELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQ 785
Query: 457 TKELR--IADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKN---ISVRLEE 511
EL+ +A + Q + ++ + E+QE + K EA KS+E++ + I+ + +
Sbjct: 786 VAELKQELATLKSQ-LNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTD 844
Query: 512 VEA--NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
VE +A++ + + + + + E+ TI IL+ ++ +L+ I +++
Sbjct: 845 VEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKE 904
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAE 596
Q ++ +L L QK+ K +L +
Sbjct: 905 QDDLLVL---LADQDQKILSLKNKLKD 928
>AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 59.7 bits (138), Expect = 3e-08
Identities = 86/385 (22%), Positives = 181/385 (47%), Gaps = 38/385 (9%)
Query: 273 LNQLNE-LKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAE------TKLKSEV 323
L + N+ L++ ++ +L I +S+ E+E L RV+E E TK +S+
Sbjct: 345 LEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 404
Query: 324 TRIKKKLQIQ---ITELELSLDVANKTNIDLQK---TIKKQSLQLTEIQTHYDEVQRQLQ 377
++KKLQ + EL L ++ K +L+K K + T++ + ++ + +
Sbjct: 405 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQYEESQTRVNELTVINVNLS 436
L++ V + R++ L E E R E+A L +K + + + V+E + +
Sbjct: 465 DLLNELEVVKSRVKEL--ECSESR--LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIK 520
Query: 437 SSKAKIE---QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV---K 490
+ K++ + + ++T++L ++ ++++E++ V +L E++ ++ K
Sbjct: 521 QEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLK 580
Query: 491 IEAVKKS-LEIEVKNISVRL---EEVEANAIVGGKRIISKL----EARIKDMELELDEEK 542
E K S L V + RL EEVE G R S+L + +IK++ LE++ K
Sbjct: 581 SEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLK 640
Query: 543 RR--HAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+R E ++ L K E + ++ + +Q + L LE+ +++ + + + E
Sbjct: 641 KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIA-KNKAIEKGEV 699
Query: 600 MSQQSVTRVRRFQRELEAAEDRADV 624
+SQ++ R R E ++ + +A+V
Sbjct: 700 VSQEAELRHRFRLEEAKSRDLKAEV 724
Score = 59.3 bits (137), Expect = 4e-08
Identities = 64/294 (21%), Positives = 145/294 (49%), Gaps = 27/294 (9%)
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K + K +L ++++ + + Q+ ++Q G+ +++Q LT ++ E E+ L+
Sbjct: 231 KRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLRE----EEEKLK--- 283
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA-------DE 465
++ + +E + ++ +L V + +S ++ +E+ A+ + ++LR+ E
Sbjct: 284 AITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIE 343
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ L+ E L E +++I K E SL EV+N+ R+ E+E G I+
Sbjct: 344 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME-----GKDEEIT 398
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K E++ +++ +L EE+ E LR + +L++ + + E+ ++ S + E T
Sbjct: 399 KTESQCRELRKKLQEEEHHSKE----LRLEVEKLQKRMSELEKLEEAFS--KSKSECTQL 452
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+++ K + ++ +++ V + R +ELE +E R + AE +L K ++F
Sbjct: 453 HLNLEKEKNLTKDLLNELEVVKSR--VKELECSESRLEKAELSLKDDLTKLKSF 504
Score = 52.0 bits (119), Expect = 7e-06
Identities = 61/348 (17%), Positives = 153/348 (43%), Gaps = 16/348 (4%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ +L +++ +L+ +LN+ K E+E +R+ +AE LK ++T++K
Sbjct: 447 SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 506
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
+ + E + ++ + + K ++ ++ +++ + + L + ++
Sbjct: 507 MLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 566
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
+LT E +E+ G + + + + R++ + + ++ +++ EL
Sbjct: 567 NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELT---C 623
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
D KEL + ER ++ +L+ L + ++ ++E ++ + + +S +LEE
Sbjct: 624 PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 683
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+ K I+K +A I+ E+ E + RH ++ K R LK + +E
Sbjct: 684 I--------KHQIAKNKA-IEKGEVVSQEAELRHR--FRLEEAKSRDLKAEVQALKEKIH 732
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ +D L + S+ +++ E+E ++ V +ELE ++
Sbjct: 733 ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSK 780
Score = 39.9 bits (89), Expect = 0.028
Identities = 78/390 (20%), Positives = 162/390 (41%), Gaps = 20/390 (5%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+KR+ E+E + + K + ELR+K S + + +E+ ++ + +
Sbjct: 384 RKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE--VEKLQKRMSELEKLEEA 441
Query: 203 FQASRTLVNRDYTNLSKNV-LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
F S++ + + NL K L K L+ + SRV E R+ + + +
Sbjct: 442 FSKSKSECTQLHLNLEKEKNLTKDLLNE--LEVVKSRVKELECSESRLEKAELS--LKDD 497
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL-- 319
T+L + +++ + E +KQ ++ V LN + K ++ + +++E KL
Sbjct: 498 LTKLKSFTVMLVDERKNMMEKIKQ-EERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 556
Query: 320 -KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
KSE+ L + EL L + + +L ++ +L I+ E+ R
Sbjct: 557 LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSR 616
Query: 379 TLDQYGVAQ-RRIQSLTGEVEEIRGNYEQALRVKRSV---EQQYEESQ----TRVNELTV 430
+ + +I+ LT E+E ++ +Q V+ + E +Y++ + T ++
Sbjct: 617 KGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 676
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
++ L K +I + AI + ELR + +LK V+ L E+ ++
Sbjct: 677 LSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMN 736
Query: 491 IEAVKKSLEIEVKNISVR-LEEVEANAIVG 519
E L+++ + R +EE N +G
Sbjct: 737 KEDQLSQLQVDYSVLQQRFMEEENKNKNMG 766
>AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 59.7 bits (138), Expect = 3e-08
Identities = 86/385 (22%), Positives = 181/385 (47%), Gaps = 38/385 (9%)
Query: 273 LNQLNE-LKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAE------TKLKSEV 323
L + N+ L++ ++ +L I +S+ E+E L RV+E E TK +S+
Sbjct: 246 LEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 305
Query: 324 TRIKKKLQIQ---ITELELSLDVANKTNIDLQK---TIKKQSLQLTEIQTHYDEVQRQLQ 377
++KKLQ + EL L ++ K +L+K K + T++ + ++ + +
Sbjct: 306 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 365
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQYEESQTRVNELTVINVNLS 436
L++ V + R++ L E E R E+A L +K + + + V+E + +
Sbjct: 366 DLLNELEVVKSRVKEL--ECSESR--LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIK 421
Query: 437 SSKAKIE---QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV---K 490
+ K++ + + ++T++L ++ ++++E++ V +L E++ ++ K
Sbjct: 422 QEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLK 481
Query: 491 IEAVKKS-LEIEVKNISVRL---EEVEANAIVGGKRIISKL----EARIKDMELELDEEK 542
E K S L V + RL EEVE G R S+L + +IK++ LE++ K
Sbjct: 482 SEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLK 541
Query: 543 RR--HAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+R E ++ L K E + ++ + +Q + L LE+ +++ + + + E
Sbjct: 542 KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIA-KNKAIEKGEV 600
Query: 600 MSQQSVTRVRRFQRELEAAEDRADV 624
+SQ++ R R E ++ + +A+V
Sbjct: 601 VSQEAELRHRFRLEEAKSRDLKAEV 625
Score = 59.3 bits (137), Expect = 4e-08
Identities = 64/294 (21%), Positives = 145/294 (49%), Gaps = 27/294 (9%)
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K + K +L ++++ + + Q+ ++Q G+ +++Q LT ++ E E+ L+
Sbjct: 132 KRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLRE----EEEKLK--- 184
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA-------DE 465
++ + +E + ++ +L V + +S ++ +E+ A+ + ++LR+ E
Sbjct: 185 AITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIE 244
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ L+ E L E +++I K E SL EV+N+ R+ E+E G I+
Sbjct: 245 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME-----GKDEEIT 299
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K E++ +++ +L EE+ E LR + +L++ + + E+ ++ S + E T
Sbjct: 300 KTESQCRELRKKLQEEEHHSKE----LRLEVEKLQKRMSELEKLEEAFS--KSKSECTQL 353
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+++ K + ++ +++ V + R +ELE +E R + AE +L K ++F
Sbjct: 354 HLNLEKEKNLTKDLLNELEVVKSR--VKELECSESRLEKAELSLKDDLTKLKSF 405
Score = 52.0 bits (119), Expect = 7e-06
Identities = 61/348 (17%), Positives = 153/348 (43%), Gaps = 16/348 (4%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ +L +++ +L+ +LN+ K E+E +R+ +AE LK ++T++K
Sbjct: 348 SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 407
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
+ + E + ++ + + K ++ ++ +++ + + L + ++
Sbjct: 408 MLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 467
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
+LT E +E+ G + + + + R++ + + ++ +++ EL
Sbjct: 468 NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELT---C 524
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
D KEL + ER ++ +L+ L + ++ ++E ++ + + +S +LEE
Sbjct: 525 PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 584
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+ K I+K +A I+ E+ E + RH ++ K R LK + +E
Sbjct: 585 I--------KHQIAKNKA-IEKGEVVSQEAELRHR--FRLEEAKSRDLKAEVQALKEKIH 633
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ +D L + S+ +++ E+E ++ V +ELE ++
Sbjct: 634 ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSK 681
Score = 39.9 bits (89), Expect = 0.028
Identities = 78/390 (20%), Positives = 162/390 (41%), Gaps = 20/390 (5%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+KR+ E+E + + K + ELR+K S + + +E+ ++ + +
Sbjct: 285 RKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE--VEKLQKRMSELEKLEEA 342
Query: 203 FQASRTLVNRDYTNLSKNV-LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
F S++ + + NL K L K L+ + SRV E R+ + + +
Sbjct: 343 FSKSKSECTQLHLNLEKEKNLTKDLLNE--LEVVKSRVKELECSESRLEKAELS--LKDD 398
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL-- 319
T+L + +++ + E +KQ ++ V LN + K ++ + +++E KL
Sbjct: 399 LTKLKSFTVMLVDERKNMMEKIKQ-EERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 457
Query: 320 -KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
KSE+ L + EL L + + +L ++ +L I+ E+ R
Sbjct: 458 LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSR 517
Query: 379 TLDQYGVAQ-RRIQSLTGEVEEIRGNYEQALRVKRSV---EQQYEESQ----TRVNELTV 430
+ + +I+ LT E+E ++ +Q V+ + E +Y++ + T ++
Sbjct: 518 KGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 577
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
++ L K +I + AI + ELR + +LK V+ L E+ ++
Sbjct: 578 LSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMN 637
Query: 491 IEAVKKSLEIEVKNISVR-LEEVEANAIVG 519
E L+++ + R +EE N +G
Sbjct: 638 KEDQLSQLQVDYSVLQQRFMEEENKNKNMG 667
>AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 59.7 bits (138), Expect = 3e-08
Identities = 86/385 (22%), Positives = 181/385 (47%), Gaps = 38/385 (9%)
Query: 273 LNQLNE-LKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAE------TKLKSEV 323
L + N+ L++ ++ +L I +S+ E+E L RV+E E TK +S+
Sbjct: 345 LEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 404
Query: 324 TRIKKKLQIQ---ITELELSLDVANKTNIDLQK---TIKKQSLQLTEIQTHYDEVQRQLQ 377
++KKLQ + EL L ++ K +L+K K + T++ + ++ + +
Sbjct: 405 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQYEESQTRVNELTVINVNLS 436
L++ V + R++ L E E R E+A L +K + + + V+E + +
Sbjct: 465 DLLNELEVVKSRVKEL--ECSESR--LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIK 520
Query: 437 SSKAKIE---QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV---K 490
+ K++ + + ++T++L ++ ++++E++ V +L E++ ++ K
Sbjct: 521 QEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLK 580
Query: 491 IEAVKKS-LEIEVKNISVRL---EEVEANAIVGGKRIISKL----EARIKDMELELDEEK 542
E K S L V + RL EEVE G R S+L + +IK++ LE++ K
Sbjct: 581 SEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLK 640
Query: 543 RR--HAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+R E ++ L K E + ++ + +Q + L LE+ +++ + + + E
Sbjct: 641 KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIA-KNKAIEKGEV 699
Query: 600 MSQQSVTRVRRFQRELEAAEDRADV 624
+SQ++ R R E ++ + +A+V
Sbjct: 700 VSQEAELRHRFRLEEAKSRDLKAEV 724
Score = 59.3 bits (137), Expect = 4e-08
Identities = 64/294 (21%), Positives = 145/294 (49%), Gaps = 27/294 (9%)
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K + K +L ++++ + + Q+ ++Q G+ +++Q LT ++ E E+ L+
Sbjct: 231 KRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLRE----EEEKLK--- 283
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA-------DE 465
++ + +E + ++ +L V + +S ++ +E+ A+ + ++LR+ E
Sbjct: 284 AITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIE 343
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ L+ E L E +++I K E SL EV+N+ R+ E+E G I+
Sbjct: 344 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME-----GKDEEIT 398
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K E++ +++ +L EE+ E LR + +L++ + + E+ ++ S + E T
Sbjct: 399 KTESQCRELRKKLQEEEHHSKE----LRLEVEKLQKRMSELEKLEEAFS--KSKSECTQL 452
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+++ K + ++ +++ V + R +ELE +E R + AE +L K ++F
Sbjct: 453 HLNLEKEKNLTKDLLNELEVVKSR--VKELECSESRLEKAELSLKDDLTKLKSF 504
Score = 52.0 bits (119), Expect = 7e-06
Identities = 61/348 (17%), Positives = 153/348 (43%), Gaps = 16/348 (4%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ +L +++ +L+ +LN+ K E+E +R+ +AE LK ++T++K
Sbjct: 447 SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 506
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
+ + E + ++ + + K ++ ++ +++ + + L + ++
Sbjct: 507 MLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 566
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
+LT E +E+ G + + + + R++ + + ++ +++ EL
Sbjct: 567 NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELT---C 623
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
D KEL + ER ++ +L+ L + ++ ++E ++ + + +S +LEE
Sbjct: 624 PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 683
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+ K I+K +A I+ E+ E + RH ++ K R LK + +E
Sbjct: 684 I--------KHQIAKNKA-IEKGEVVSQEAELRHR--FRLEEAKSRDLKAEVQALKEKIH 732
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ +D L + S+ +++ E+E ++ V +ELE ++
Sbjct: 733 ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSK 780
Score = 39.9 bits (89), Expect = 0.028
Identities = 78/390 (20%), Positives = 162/390 (41%), Gaps = 20/390 (5%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+KR+ E+E + + K + ELR+K S + + +E+ ++ + +
Sbjct: 384 RKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE--VEKLQKRMSELEKLEEA 441
Query: 203 FQASRTLVNRDYTNLSKNV-LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
F S++ + + NL K L K L+ + SRV E R+ + + +
Sbjct: 442 FSKSKSECTQLHLNLEKEKNLTKDLLNE--LEVVKSRVKELECSESRLEKAELS--LKDD 497
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL-- 319
T+L + +++ + E +KQ ++ V LN + K ++ + +++E KL
Sbjct: 498 LTKLKSFTVMLVDERKNMMEKIKQ-EERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 556
Query: 320 -KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
KSE+ L + EL L + + +L ++ +L I+ E+ R
Sbjct: 557 LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSR 616
Query: 379 TLDQYGVAQ-RRIQSLTGEVEEIRGNYEQALRVKRSV---EQQYEESQ----TRVNELTV 430
+ + +I+ LT E+E ++ +Q V+ + E +Y++ + T ++
Sbjct: 617 KGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 676
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
++ L K +I + AI + ELR + +LK V+ L E+ ++
Sbjct: 677 LSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMN 736
Query: 491 IEAVKKSLEIEVKNISVR-LEEVEANAIVG 519
E L+++ + R +EE N +G
Sbjct: 737 KEDQLSQLQVDYSVLQQRFMEEENKNKNMG 766
>AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 59.7 bits (138), Expect = 3e-08
Identities = 86/385 (22%), Positives = 181/385 (47%), Gaps = 38/385 (9%)
Query: 273 LNQLNE-LKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAE------TKLKSEV 323
L + N+ L++ ++ +L I +S+ E+E L RV+E E TK +S+
Sbjct: 246 LEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 305
Query: 324 TRIKKKLQIQ---ITELELSLDVANKTNIDLQK---TIKKQSLQLTEIQTHYDEVQRQLQ 377
++KKLQ + EL L ++ K +L+K K + T++ + ++ + +
Sbjct: 306 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 365
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQYEESQTRVNELTVINVNLS 436
L++ V + R++ L E E R E+A L +K + + + V+E + +
Sbjct: 366 DLLNELEVVKSRVKEL--ECSESR--LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIK 421
Query: 437 SSKAKIE---QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV---K 490
+ K++ + + ++T++L ++ ++++E++ V +L E++ ++ K
Sbjct: 422 QEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLK 481
Query: 491 IEAVKKS-LEIEVKNISVRL---EEVEANAIVGGKRIISKL----EARIKDMELELDEEK 542
E K S L V + RL EEVE G R S+L + +IK++ LE++ K
Sbjct: 482 SEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLK 541
Query: 543 RR--HAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+R E ++ L K E + ++ + +Q + L LE+ +++ + + + E
Sbjct: 542 KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIA-KNKAIEKGEV 600
Query: 600 MSQQSVTRVRRFQRELEAAEDRADV 624
+SQ++ R R E ++ + +A+V
Sbjct: 601 VSQEAELRHRFRLEEAKSRDLKAEV 625
Score = 59.3 bits (137), Expect = 4e-08
Identities = 64/294 (21%), Positives = 145/294 (49%), Gaps = 27/294 (9%)
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K + K +L ++++ + + Q+ ++Q G+ +++Q LT ++ E E+ L+
Sbjct: 132 KRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLRE----EEEKLK--- 184
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA-------DE 465
++ + +E + ++ +L V + +S ++ +E+ A+ + ++LR+ E
Sbjct: 185 AITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIE 244
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ L+ E L E +++I K E SL EV+N+ R+ E+E G I+
Sbjct: 245 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME-----GKDEEIT 299
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K E++ +++ +L EE+ E LR + +L++ + + E+ ++ S + E T
Sbjct: 300 KTESQCRELRKKLQEEEHHSKE----LRLEVEKLQKRMSELEKLEEAFS--KSKSECTQL 353
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+++ K + ++ +++ V + R +ELE +E R + AE +L K ++F
Sbjct: 354 HLNLEKEKNLTKDLLNELEVVKSR--VKELECSESRLEKAELSLKDDLTKLKSF 405
Score = 52.0 bits (119), Expect = 7e-06
Identities = 61/348 (17%), Positives = 153/348 (43%), Gaps = 16/348 (4%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ +L +++ +L+ +LN+ K E+E +R+ +AE LK ++T++K
Sbjct: 348 SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 407
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
+ + E + ++ + + K ++ ++ +++ + + L + ++
Sbjct: 408 MLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 467
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
+LT E +E+ G + + + + R++ + + ++ +++ EL
Sbjct: 468 NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELT---C 524
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
D KEL + ER ++ +L+ L + ++ ++E ++ + + +S +LEE
Sbjct: 525 PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 584
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+ K I+K +A I+ E+ E + RH ++ K R LK + +E
Sbjct: 585 I--------KHQIAKNKA-IEKGEVVSQEAELRHR--FRLEEAKSRDLKAEVQALKEKIH 633
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ +D L + S+ +++ E+E ++ V +ELE ++
Sbjct: 634 ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSK 681
Score = 39.9 bits (89), Expect = 0.028
Identities = 78/390 (20%), Positives = 162/390 (41%), Gaps = 20/390 (5%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+KR+ E+E + + K + ELR+K S + + +E+ ++ + +
Sbjct: 285 RKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE--VEKLQKRMSELEKLEEA 342
Query: 203 FQASRTLVNRDYTNLSKNV-LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
F S++ + + NL K L K L+ + SRV E R+ + + +
Sbjct: 343 FSKSKSECTQLHLNLEKEKNLTKDLLNE--LEVVKSRVKELECSESRLEKAELS--LKDD 398
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL-- 319
T+L + +++ + E +KQ ++ V LN + K ++ + +++E KL
Sbjct: 399 LTKLKSFTVMLVDERKNMMEKIKQ-EERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 457
Query: 320 -KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
KSE+ L + EL L + + +L ++ +L I+ E+ R
Sbjct: 458 LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSR 517
Query: 379 TLDQYGVAQ-RRIQSLTGEVEEIRGNYEQALRVKRSV---EQQYEESQ----TRVNELTV 430
+ + +I+ LT E+E ++ +Q V+ + E +Y++ + T ++
Sbjct: 518 KGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 577
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
++ L K +I + AI + ELR + +LK V+ L E+ ++
Sbjct: 578 LSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMN 637
Query: 491 IEAVKKSLEIEVKNISVR-LEEVEANAIVG 519
E L+++ + R +EE N +G
Sbjct: 638 KEDQLSQLQVDYSVLQQRFMEEENKNKNMG 667
>AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/255 (19%), Positives = 123/255 (48%), Gaps = 10/255 (3%)
Query: 299 KQTSIE-IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKK 357
K+ +I+ EQ A +AE + K ++ ++ LQ ++ E ++ +++ + Q+ +++
Sbjct: 15 KENAIDRAEQAEADKKQAEDRCK-QLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQ 73
Query: 358 QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE-- 415
+ T+ + + R++Q+ ++ AQ R+ + ++EE +++ R + +E
Sbjct: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR 133
Query: 416 -----QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
++ E + ++ E I + ++ ++L I+ + + + +A+ + +
Sbjct: 134 AMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDL 193
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
+ ELK +L + + K + E E+K + +L+E E A +R ++KLE
Sbjct: 194 EEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEF-AERSVAKLEKT 252
Query: 531 IKDMELELDEEKRRH 545
I D+E E+ +K ++
Sbjct: 253 IDDLEDEVYAQKMKY 267
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/195 (25%), Positives = 100/195 (51%), Gaps = 26/195 (13%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI-EAVKKSLE 499
K+++E AI A+ E K+ A++R ++++ E + + L ++ + K E+VK++ E
Sbjct: 12 KLDKENAIDRAEQAEADKKQ--AEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQE 69
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+LE+ E A + ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 70 --------KLEQAEKKA-TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA- 119
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------ 613
+E ++ + ++++ K +K+ + + QL E + +++ S + R
Sbjct: 120 ------ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 173
Query: 614 -ELEAAEDRADVAES 627
ELE +E+RA+VAES
Sbjct: 174 GELERSEERAEVAES 188
>AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 59.7 bits (138), Expect = 3e-08
Identities = 50/257 (19%), Positives = 121/257 (47%), Gaps = 10/257 (3%)
Query: 299 KQTSIE-IEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKK 357
K+ +I+ EQ A +AE + K ++ ++ LQ ++ E ++ +++ + Q+ +++
Sbjct: 15 KENAIDRAEQAEADKKQAEDRCK-QLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQ 73
Query: 358 QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVE-- 415
+ T+ + + R++Q+ ++ AQ R+ + ++EE +++ R + +E
Sbjct: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR 133
Query: 416 -----QQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRV 470
++ E + ++ E I + ++ ++L I+ + + + +A+ + +
Sbjct: 134 AMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDL 193
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
+ ELK +L + + K + E E+K + +L+E E A +R ++KLE
Sbjct: 194 EEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEF-AERSVAKLEKT 252
Query: 531 IKDMELELDEEKRRHAE 547
I D+E L K + E
Sbjct: 253 IDDLEETLASAKEENVE 269
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/195 (25%), Positives = 100/195 (51%), Gaps = 26/195 (13%)
Query: 441 KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKI-EAVKKSLE 499
K+++E AI A+ E K+ A++R ++++ E + + L ++ + K E+VK++ E
Sbjct: 12 KLDKENAIDRAEQAEADKKQ--AEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQE 69
Query: 500 IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQL 559
+LE+ E A + ++ L RI+ +E ELD + R A ++ L + E+
Sbjct: 70 --------KLEQAEKKA-TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA- 119
Query: 560 KEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQR------ 613
+E ++ + ++++ K +K+ + + QL E + +++ S + R
Sbjct: 120 ------ADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILE 173
Query: 614 -ELEAAEDRADVAES 627
ELE +E+RA+VAES
Sbjct: 174 GELERSEERAEVAES 188
Score = 33.9 bits (74), Expect = 1.8
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 278 ELKETVKQFDDLSVYILNDSSKQTSIE--IEQLNARVVEAETKLKSEVTRIKKKLQIQIT 335
ELK L S+K+ E I+ L ++ EAET+ + R KL+ I
Sbjct: 196 ELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEF-AERSVAKLEKTID 254
Query: 336 ELELSLDVANKTNIDLQKTIKKQSLQLTEI 365
+LE +L A + N+++ +T+ + L+L +
Sbjct: 255 DLEETLASAKEENVEIHQTLDQTLLELNNL 284
>AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protein
90 protein.
Length = 764
Score = 59.7 bits (138), Expect = 3e-08
Identities = 92/489 (18%), Positives = 215/489 (43%), Gaps = 42/489 (8%)
Query: 154 DLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPDFQASRTLVNRD 213
D+YEK +N EL + ++ + + Q L+ E R + + + + + + +++
Sbjct: 134 DIYEKPMN---ELDKVVEKHKESYRRILGQLLVAEKSRR---QTILELEEEKRK---HKE 184
Query: 214 YTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSYL 273
Y S + E + + + +S E + +E TT + EL + + L
Sbjct: 185 YMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTT----LKEELTKLKSFAL 240
Query: 274 NQLNELKETVKQF--DDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++E + Q + L ++K+T ++ ARV E E K TR++K+LQ
Sbjct: 241 MVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQK----ATRLEKELQ 296
Query: 332 IQITELELSLD--VANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
Q T+ D +A TN D Q +Q +L + DE L+ T A+
Sbjct: 297 TQTTKFHQDQDTIMAKLTNEDSQNRQLQQ--KLAALSRQIDE----LEETNRSLRKAEEE 350
Query: 390 IQSLTGEVEEIRGNYEQA--LRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELA 447
+Q + ++ +G Y A + + ++ + + + EL + ++E+E
Sbjct: 351 LQDIKEKIS--KGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERE-T 407
Query: 448 IVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISV 507
+ + D+ ++L ++++ + + + + + K K L E++++ V
Sbjct: 408 LQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKV 467
Query: 508 RLEEVEA--NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQ 565
R++E+EA + + + + + ++K + + +E++ +E +K K E +L+ Q
Sbjct: 468 RIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLK---KTEDKLQAASSQ 524
Query: 566 CEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR-RFQRELEAAEDRADV 624
+ +Q ++ + + L + +++ K + E+ SVT+ R + +L+A E++ +
Sbjct: 525 LQVEQNKVTTVTEKLIEETKRALKSKTDVEEK----MYSVTKERDDLKNKLKAEEEKGND 580
Query: 625 AESNLSLIR 633
S +++++
Sbjct: 581 LLSRVNMLK 589
Score = 35.5 bits (78), Expect = 0.61
Identities = 43/216 (19%), Positives = 99/216 (45%), Gaps = 11/216 (5%)
Query: 297 SSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELE----LSLDVANKTNIDLQ 352
++KQ S E+E L R+ E E ++S + + + L+ +T+L+ + +D + L+
Sbjct: 454 TTKQLSQELESLKVRIKELEA-IESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLK 512
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
KT K +++Q ++V + +++ +R ++S T E++ ++ +K
Sbjct: 513 KTEDKLQAASSQLQVEQNKVTTVTEKLIEE---TKRALKSKTDVEEKMYSVTKERDDLKN 569
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQT 472
++ + E+ ++ + ++ L S +A IE++ + D K + +++
Sbjct: 570 KLKAEEEKGNDLLSRVNMLKNRLQSLEA-IEKDFLKNKLNQDS-GKSTTALHQENNKIK- 626
Query: 473 ELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVR 508
EL VE L + + + IE E E + + R
Sbjct: 627 ELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERR 662
>AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein.
Length = 1213
Score = 59.7 bits (138), Expect = 3e-08
Identities = 86/385 (22%), Positives = 181/385 (47%), Gaps = 38/385 (9%)
Query: 273 LNQLNE-LKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAE------TKLKSEV 323
L + N+ L++ ++ +L I +S+ E+E L RV+E E TK +S+
Sbjct: 345 LEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 404
Query: 324 TRIKKKLQIQ---ITELELSLDVANKTNIDLQK---TIKKQSLQLTEIQTHYDEVQRQLQ 377
++KKLQ + EL L ++ K +L+K K + T++ + ++ + +
Sbjct: 405 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQYEESQTRVNELTVINVNLS 436
L++ V + R++ L E E R E+A L +K + + + V+E + +
Sbjct: 465 DLLNELEVVKSRVKEL--ECSESR--LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIK 520
Query: 437 SSKAKIE---QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV---K 490
+ K++ + + ++T++L ++ ++++E++ V +L E++ ++ K
Sbjct: 521 QEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLK 580
Query: 491 IEAVKKS-LEIEVKNISVRL---EEVEANAIVGGKRIISKL----EARIKDMELELDEEK 542
E K S L V + RL EEVE G R S+L + +IK++ LE++ K
Sbjct: 581 SEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLK 640
Query: 543 RR--HAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+R E ++ L K E + ++ + +Q + L LE+ +++ + + + E
Sbjct: 641 KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIA-KNKAIEKGEV 699
Query: 600 MSQQSVTRVRRFQRELEAAEDRADV 624
+SQ++ R R E ++ + +A+V
Sbjct: 700 VSQEAELRHRFRLEEAKSRDLKAEV 724
Score = 59.3 bits (137), Expect = 4e-08
Identities = 64/294 (21%), Positives = 145/294 (49%), Gaps = 27/294 (9%)
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K + K +L ++++ + + Q+ ++Q G+ +++Q LT ++ E E+ L+
Sbjct: 231 KRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLRE----EEEKLK--- 283
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA-------DE 465
++ + +E + ++ +L V + +S ++ +E+ A+ + ++LR+ E
Sbjct: 284 AITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIE 343
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ L+ E L E +++I K E SL EV+N+ R+ E+E G I+
Sbjct: 344 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME-----GKDEEIT 398
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K E++ +++ +L EE+ E LR + +L++ + + E+ ++ S + E T
Sbjct: 399 KTESQCRELRKKLQEEEHHSKE----LRLEVEKLQKRMSELEKLEEAFS--KSKSECTQL 452
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+++ K + ++ +++ V + R +ELE +E R + AE +L K ++F
Sbjct: 453 HLNLEKEKNLTKDLLNELEVVKSR--VKELECSESRLEKAELSLKDDLTKLKSF 504
Score = 52.0 bits (119), Expect = 7e-06
Identities = 61/348 (17%), Positives = 153/348 (43%), Gaps = 16/348 (4%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ +L +++ +L+ +LN+ K E+E +R+ +AE LK ++T++K
Sbjct: 447 SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 506
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
+ + E + ++ + + K ++ ++ +++ + + L + ++
Sbjct: 507 MLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 566
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
+LT E +E+ G + + + + R++ + + ++ +++ EL
Sbjct: 567 NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELT---C 623
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
D KEL + ER ++ +L+ L + ++ ++E ++ + + +S +LEE
Sbjct: 624 PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 683
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+ K I+K +A I+ E+ E + RH ++ K R LK + +E
Sbjct: 684 I--------KHQIAKNKA-IEKGEVVSQEAELRHR--FRLEEAKSRDLKAEVQALKEKIH 732
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ +D L + S+ +++ E+E ++ V +ELE ++
Sbjct: 733 ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSK 780
Score = 39.9 bits (89), Expect = 0.028
Identities = 78/390 (20%), Positives = 162/390 (41%), Gaps = 20/390 (5%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+KR+ E+E + + K + ELR+K S + + +E+ ++ + +
Sbjct: 384 RKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE--VEKLQKRMSELEKLEEA 441
Query: 203 FQASRTLVNRDYTNLSKNV-LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
F S++ + + NL K L K L+ + SRV E R+ + + +
Sbjct: 442 FSKSKSECTQLHLNLEKEKNLTKDLLNE--LEVVKSRVKELECSESRLEKAELS--LKDD 497
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL-- 319
T+L + +++ + E +KQ ++ V LN + K ++ + +++E KL
Sbjct: 498 LTKLKSFTVMLVDERKNMMEKIKQ-EERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 556
Query: 320 -KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
KSE+ L + EL L + + +L ++ +L I+ E+ R
Sbjct: 557 LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSR 616
Query: 379 TLDQYGVAQ-RRIQSLTGEVEEIRGNYEQALRVKRSV---EQQYEESQ----TRVNELTV 430
+ + +I+ LT E+E ++ +Q V+ + E +Y++ + T ++
Sbjct: 617 KGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 676
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
++ L K +I + AI + ELR + +LK V+ L E+ ++
Sbjct: 677 LSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMN 736
Query: 491 IEAVKKSLEIEVKNISVR-LEEVEANAIVG 519
E L+++ + R +EE N +G
Sbjct: 737 KEDQLSQLQVDYSVLQQRFMEEENKNKNMG 766
>AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein.
Length = 1140
Score = 59.7 bits (138), Expect = 3e-08
Identities = 86/385 (22%), Positives = 181/385 (47%), Gaps = 38/385 (9%)
Query: 273 LNQLNE-LKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAE------TKLKSEV 323
L + N+ L++ ++ +L I +S+ E+E L RV+E E TK +S+
Sbjct: 272 LEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 331
Query: 324 TRIKKKLQIQ---ITELELSLDVANKTNIDLQK---TIKKQSLQLTEIQTHYDEVQRQLQ 377
++KKLQ + EL L ++ K +L+K K + T++ + ++ + +
Sbjct: 332 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 391
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQYEESQTRVNELTVINVNLS 436
L++ V + R++ L E E R E+A L +K + + + V+E + +
Sbjct: 392 DLLNELEVVKSRVKEL--ECSESR--LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIK 447
Query: 437 SSKAKIE---QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV---K 490
+ K++ + + ++T++L ++ ++++E++ V +L E++ ++ K
Sbjct: 448 QEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLK 507
Query: 491 IEAVKKS-LEIEVKNISVRL---EEVEANAIVGGKRIISKL----EARIKDMELELDEEK 542
E K S L V + RL EEVE G R S+L + +IK++ LE++ K
Sbjct: 508 SEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLK 567
Query: 543 RR--HAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+R E ++ L K E + ++ + +Q + L LE+ +++ + + + E
Sbjct: 568 KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIA-KNKAIEKGEV 626
Query: 600 MSQQSVTRVRRFQRELEAAEDRADV 624
+SQ++ R R E ++ + +A+V
Sbjct: 627 VSQEAELRHRFRLEEAKSRDLKAEV 651
Score = 59.3 bits (137), Expect = 4e-08
Identities = 64/294 (21%), Positives = 145/294 (49%), Gaps = 27/294 (9%)
Query: 353 KTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKR 412
K + K +L ++++ + + Q+ ++Q G+ +++Q LT ++ E E+ L+
Sbjct: 158 KRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLRE----EEEKLK--- 210
Query: 413 SVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIA-------DE 465
++ + +E + ++ +L V + +S ++ +E+ A+ + ++LR+ E
Sbjct: 211 AITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIE 270
Query: 466 RYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIIS 525
+ L+ E L E +++I K E SL EV+N+ R+ E+E G I+
Sbjct: 271 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME-----GKDEEIT 325
Query: 526 KLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQ 585
K E++ +++ +L EE+ E LR + +L++ + + E+ ++ S + E T
Sbjct: 326 KTESQCRELRKKLQEEEHHSKE----LRLEVEKLQKRMSELEKLEEAFS--KSKSECTQL 379
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+++ K + ++ +++ V + R +ELE +E R + AE +L K ++F
Sbjct: 380 HLNLEKEKNLTKDLLNELEVVKSR--VKELECSESRLEKAELSLKDDLTKLKSF 431
Score = 52.0 bits (119), Expect = 7e-06
Identities = 61/348 (17%), Positives = 153/348 (43%), Gaps = 16/348 (4%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ +L +++ +L+ +LN+ K E+E +R+ +AE LK ++T++K
Sbjct: 374 SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 433
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
+ + E + ++ + + K ++ ++ +++ + + L + ++
Sbjct: 434 MLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 493
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
+LT E +E+ G + + + + R++ + + ++ +++ EL
Sbjct: 494 NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELT---C 550
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
D KEL + ER ++ +L+ L + ++ ++E ++ + + +S +LEE
Sbjct: 551 PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 610
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+ K I+K +A I+ E+ E + RH ++ K R LK + +E
Sbjct: 611 I--------KHQIAKNKA-IEKGEVVSQEAELRHR--FRLEEAKSRDLKAEVQALKEKIH 659
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ +D L + S+ +++ E+E ++ V +ELE ++
Sbjct: 660 ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSK 707
Score = 39.9 bits (89), Expect = 0.028
Identities = 78/390 (20%), Positives = 162/390 (41%), Gaps = 20/390 (5%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEESRRNVQNERMYKPD 202
+KR+ E+E + + K + ELR+K S + + +E+ ++ + +
Sbjct: 311 RKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE--VEKLQKRMSELEKLEEA 368
Query: 203 FQASRTLVNRDYTNLSKNV-LAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRI 261
F S++ + + NL K L K L+ + SRV E R+ + + +
Sbjct: 369 FSKSKSECTQLHLNLEKEKNLTKDLLNE--LEVVKSRVKELECSESRLEKAELS--LKDD 424
Query: 262 NTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL-- 319
T+L + +++ + E +KQ ++ V LN + K ++ + +++E KL
Sbjct: 425 LTKLKSFTVMLVDERKNMMEKIKQ-EERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 483
Query: 320 -KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
KSE+ L + EL L + + +L ++ +L I+ E+ R
Sbjct: 484 LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSR 543
Query: 379 TLDQYGVAQ-RRIQSLTGEVEEIRGNYEQALRVKRSV---EQQYEESQ----TRVNELTV 430
+ + +I+ LT E+E ++ +Q V+ + E +Y++ + T ++
Sbjct: 544 KGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANF 603
Query: 431 INVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVK 490
++ L K +I + AI + ELR + +LK V+ L E+ ++
Sbjct: 604 LSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMN 663
Query: 491 IEAVKKSLEIEVKNISVR-LEEVEANAIVG 519
E L+++ + R +EE N +G
Sbjct: 664 KEDQLSQLQVDYSVLQQRFMEEENKNKNMG 693
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 59.3 bits (137), Expect = 4e-08
Identities = 83/477 (17%), Positives = 206/477 (43%), Gaps = 31/477 (6%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEES----RRNVQNERM 198
+ ++ ++ KE +L KE ++ + +KA+ L+E+ R + E +
Sbjct: 2054 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEV 2113
Query: 199 YKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCV 258
++ + V + + +A+ L E + N E++ +++ E + +
Sbjct: 2114 HQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVI 2173
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+ ++ + Q+ E+ ++K F+ L + L + + +I++ ++ E +
Sbjct: 2174 LDAENSKAEVE-TLKTQIEEMARSLKVFE-LDLVTLRSEKENLTKQIQEKQGQLSELDKL 2231
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L S + +++K Q +I E S KT +++ + K+ + E+ + +
Sbjct: 2232 LSSFKSLLEEKEQAEIQIKEES-----KTAVEMLQNQLKELNEAVAALCGDQEIMKATEQ 2286
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-----------E 427
+LD + ++++ +E++R E + + V QQ +ES+ + E
Sbjct: 2287 SLDPPIEEEHQLRN---SIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERE 2343
Query: 428 LTVINVNLSSSKAKIEQ---ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
L + N + + E E+ + A + +T+ LR + +++E ++ L +E
Sbjct: 2344 LEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKE 2403
Query: 485 QERIVKIEAVKKSLE---IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE 541
QERI ++E + S E E + V+++E + A+ + + +L R+ + + +
Sbjct: 2404 QERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEAC 2463
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
K + + E + +++ +E + N +LQ S+ Q+V K++L +++
Sbjct: 2464 KAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKD 2520
Score = 57.2 bits (132), Expect = 2e-07
Identities = 98/441 (22%), Positives = 197/441 (44%), Gaps = 34/441 (7%)
Query: 219 KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSY--LNQL 276
K + + LM+++ M+ S V E+ +++E + V T L A++N L L
Sbjct: 859 KGEIEENLMKAEQMHQ--SFVAETSQRISKLQEDTSAHQNVVAET-LSALENKEKELQLL 915
Query: 277 NELKETVK-QFDDL--SVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N+ ET + + +L S ++L DS K+ QL + + E K S + + K+ +
Sbjct: 916 NDKVETEQAEIQELKKSNHLLEDSLKEL-----QLLSETLSLEKKEMSSIISLNKR---E 967
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY-DEVQRQLQVTLDQYGVAQRRIQS 392
I EL + N L + K +Q +E +Y DE ++ + DQY Q ++
Sbjct: 968 IEELTQENGTLKEINASLNQE-KMNLIQKSESFANYIDEREKSISELSDQY--KQEKL-I 1023
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
L EE YE + ++ +++ + + +NE T + N K ++EQ A +
Sbjct: 1024 LLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCEN---RKNELEQLKEAFAKE 1080
Query: 453 YDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
+ E +L A+ER Q + EL+ + L E + + KS +K + L+E
Sbjct: 1081 HQEFLTKLAFAEERNQNLMLELETVQQALRSE---MTDNQNNSKSEAGGLKQEIMTLKE- 1136
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCE-EDQK 571
E N + K + L+ + M++ + + ++ E+ + +R ++ + QC + Q
Sbjct: 1137 EQNKM--QKEVNDLLQENEQLMKVMKTKHECQNLES-EPIRNSVKERESERNQCNFKPQM 1193
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ + + SL+ + ++ + L +E Q+S Q EL+ R D+ SNL
Sbjct: 1194 DLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTI--RGDLETSNLQD 1251
Query: 632 IRAKHRTFVTTSTVPGSQVYL 652
++++ + + + + Y+
Sbjct: 1252 MQSQEISGLKDCEIDAEEKYI 1272
Score = 56.4 bits (130), Expect = 3e-07
Identities = 57/346 (16%), Positives = 145/346 (41%), Gaps = 25/346 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQI 332
N+L+ ++ + ++Y+ + +E+ Q +E + + K +V ++++L +
Sbjct: 1901 NELSRIRSEKASIEHEALYL------EADLEVVQTEKLCLEKDNENKQKVIVCLEEELSV 1954
Query: 333 QITE---LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
+E L LD +K L + +K + E+++H E +QV +
Sbjct: 1955 VTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTEL 2014
Query: 390 IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIV 449
+Q+L+ +V E+ L+ K ++++ + + L++ L + A++ +E ++
Sbjct: 2015 LQTLSSDVSEL-------LKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELL 2067
Query: 450 AADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRL 509
+ + + L +D V L+ + E R+ + L ++ + VR+
Sbjct: 2068 VKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRI 2127
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
E E + + ++K+ E E D K + + L+ E + VI+ E
Sbjct: 2128 EADEKKQL--------HIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENS 2179
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ + L+ +E+ ++ + +++ L + +++ Q +L
Sbjct: 2180 KAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQL 2225
Score = 54.4 bits (125), Expect = 1e-06
Identities = 95/494 (19%), Positives = 215/494 (43%), Gaps = 41/494 (8%)
Query: 152 ELDLY----EKEVNLGSELRQKAAMYRGKSAKAIA--QTLLEESRRNVQNERMYKPDFQA 205
ELDL EKE NL ++++K + K ++ ++LLEE Q E K + +
Sbjct: 2201 ELDLVTLRSEKE-NLTKQIQEKQGQL-SELDKLLSSFKSLLEEKE---QAEIQIKEESKT 2255
Query: 206 SRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTEL 265
+ ++ L++ V A + + M + + + I E ++R + + ++ L
Sbjct: 2256 AVEMLQNQLKELNEAVAALC-GDQEIMKATEQSLDPPIEEEHQLRNS-----IEKLRARL 2309
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNAR--VVEAETKLKSEV 323
A + L L +LKE+ D L + N + +EI + N +EAE K EV
Sbjct: 2310 EADEKKQLCVLQQLKESEHHADLLKGRVEN---LERELEIARTNQEHAALEAENS-KGEV 2365
Query: 324 TRIKKKLQIQITELE-LSLDV----ANKTNI--DLQKTIKKQSLQLTEIQTHYDEV-QRQ 375
+K K++ L L LDV + K N+ +LQK ++ S +L I + ++ + Q +
Sbjct: 2366 ETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERIS-ELEIINSSFENILQEK 2424
Query: 376 LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
Q + + ++ L +++E+ + + + + + ++V L + L
Sbjct: 2425 EQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQL 2484
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ + ++ + + + +E+ ++ ++ E+ + ++++ + K+ V+
Sbjct: 2485 LQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVE 2544
Query: 496 ------KSLEIEVKNISVRLEE---VEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
K +E++N++V LE+ V + + + L++ K++E EL+ K
Sbjct: 2545 GEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKM 2604
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
++ + K + E+ + E + + LQ+ L +++ + L E+ S+ +
Sbjct: 2605 SFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLK 2664
Query: 607 RVRRFQRELEAAED 620
+ EL+ + D
Sbjct: 2665 ELTLENSELKKSLD 2678
Score = 51.2 bits (117), Expect = 1e-05
Identities = 75/346 (21%), Positives = 151/346 (43%), Gaps = 20/346 (5%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+EL T Q+D S K + E L+ + AE+ S +IK+K + + E
Sbjct: 341 DELVRTTAQYDQASTKYTALEQKLKKLT-EDLSCQRQNAESARCSLEQKIKEK-EKEFQE 398
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
ELS + +D Q+ I+ ++ E+Q + LQ LD+ ++++++ E
Sbjct: 399 -ELSRQQRSFQTLD-QECIQMKARLTQELQ-QAKNMHNVLQAELDKLTSVKQQLENNLEE 455
Query: 397 VEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEI 456
++ EQA + + E + S + E+ N L S + +E+ + A+ I
Sbjct: 456 FKQKLCRAEQAFQASQIKENELRRS---MEEMKKENNLLKSHSEQKAREVCHLEAELKNI 512
Query: 457 TKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANA 516
+ L + + ++ + L + QE KI + SL +E ++V E + +
Sbjct: 513 KQCLNQSQNFAEEMKAKNTSQETMLRDLQE---KINQQENSLTLEKLKLAVADLEKQRDC 569
Query: 517 IVGGKRIISKLEARIKDMELELDEEKRRHAETIKI--LRKKERQLKE--VIIQC--EEDQ 570
+ ++ K E I+ + +L + ++ + L+KKE +LKE + C E++
Sbjct: 570 ---SQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYELKEEKTLFSCWKSENE 626
Query: 571 KNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
K ++ ++ E K++ + L Q+ S + RVR + + E
Sbjct: 627 KLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRE 672
Score = 50.4 bits (115), Expect = 2e-05
Identities = 67/383 (17%), Positives = 174/383 (45%), Gaps = 27/383 (7%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ T++ + + +++N L ET + + + N+ + ++ E L+ + L
Sbjct: 627 KLLTQMESEKENLQSKINHL-ETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 685
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
S+ ++ + ++ EL+ + +++ + QK I+ L+ +++ ++++ +LQ+
Sbjct: 686 DSKSVEVETQ-KLAYMELQQKAEFSDQKH---QKEIENMCLKTSQLTGQVEDLEHKLQLL 741
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN---VNLS 436
++ R Q L E E +R + ++ + ++ S ++ ++ N+
Sbjct: 742 SNEIMDKDRCYQDLHAEYESLR-DLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANII 800
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKK 496
+ + E + + D+ K I R ++ L+ + + Q++ ++ +K
Sbjct: 801 GEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKG 860
Query: 497 SLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKE 556
+E +N+ ++ E++ + + + ISKL+ + + AET+ L KE
Sbjct: 861 EIE---ENL-MKAEQMHQSFVAETSQRISKLQE-------DTSAHQNVVAETLSALENKE 909
Query: 557 RQLKEVIIQCEEDQKNISLLQDS---LEKTSQKVSIYKRQLA-EQEGMSQQSVTRVRRFQ 612
++L+ + + E +Q I L+ S LE + +++ + L+ E++ MS S+ + + +
Sbjct: 910 KELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMS--SIISLNKRE 967
Query: 613 RELEAAEDRADVAESNLSLIRAK 635
E E ++ + E N SL + K
Sbjct: 968 IE-ELTQENGTLKEINASLNQEK 989
Score = 46.8 bits (106), Expect = 2e-04
Identities = 70/319 (21%), Positives = 140/319 (43%), Gaps = 13/319 (4%)
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAETKLKSE 322
L + +SY N NEL+ T + ++K+T + E+ ++ + E + +L E
Sbjct: 2582 LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGE 2641
Query: 323 VTRIKKKLQIQITELELSLDVANKT---NIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
R+ +LQ+ + E++ S D + N +L+K++ E + E + Q+
Sbjct: 2642 KNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR 2701
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVNLSSS 438
L + A+++ Q+L + + Q R K + +++ SQ ++ L L++S
Sbjct: 2702 LHE---AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNS 2758
Query: 439 -KA--KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
KA +I +EL D + +L+ +ER Q L + + L EE+E + K +
Sbjct: 2759 LKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQL 2818
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
++ + + K +V +V+ K + LE + K+ + LD+ K+ + K
Sbjct: 2819 QAAQEKQKTGTVMDTKVD-ELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAK 2877
Query: 556 ERQLKEVIIQCEEDQKNIS 574
E +V C + K S
Sbjct: 2878 EMLETQVAHLCSQQSKQDS 2896
Score = 46.0 bits (104), Expect = 4e-04
Identities = 69/362 (19%), Positives = 174/362 (48%), Gaps = 31/362 (8%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L +++ +I +L R+ E ++K +V + ++ LQ+Q+ + ++ L K +
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQE-LQLQLEKAKVELIEKEKVLNKCRD 341
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ----SLTGEVEEIRGNYEQAL- 408
+ + + Q + T Y ++++L+ + ++ + SL +++E +++ L
Sbjct: 342 ELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELS 401
Query: 409 RVKRS---VEQQYEESQTRVNELTVINVNLSS-SKAKIEQELAI---VAADYDEITKELR 461
R +RS ++Q+ + + R+ + N+ + +A++++ ++ + + +E ++L
Sbjct: 402 RQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLC 461
Query: 462 IADERYQRVQ---TELKHTVEHLHEEQERIVKIEAVKKS-----LEIEVKNISVRLEEVE 513
A++ +Q Q EL+ ++E + +E ++K + +K+ LE E+KNI L + +
Sbjct: 462 RAEQAFQASQIKENELRRSMEEMKKE-NNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQ 520
Query: 514 ANAIVGGKRIISKLEARIKDMELELD-EEKRRHAETIKIL---RKKERQLKEVIIQCEED 569
N K + E ++D++ +++ +E E +K+ +K+R + +++ E
Sbjct: 521 -NFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKRE- 578
Query: 570 QKNISLLQDSLEKTSQ--KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAES 627
+I L D L KT + K + +L ++E ++ T ++ E E + + +
Sbjct: 579 -HHIEQLNDKLSKTEKESKALLSALELKKKEYELKEEKTLFSCWKSENEKLLTQMESEKE 637
Query: 628 NL 629
NL
Sbjct: 638 NL 639
Score = 45.2 bits (102), Expect = 7e-04
Identities = 105/539 (19%), Positives = 232/539 (43%), Gaps = 64/539 (11%)
Query: 144 KRMQEIEKELDLYEKEV-NLGSELR-----QKAAMYRGKSAKAIAQTLLEESRRNVQNER 197
++++E E DL + V NL EL Q+ A +++K +TL + Q+ R
Sbjct: 2321 QQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLR 2380
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSC-DSRVTESITETVRVRETSPT- 255
+ D R+ L K + + E + +NS ++ + E E V+++E S T
Sbjct: 2381 GLELDVVTIRSEKENLTNELQKE--QERISELEIINSSFENILQEKEQEKVQMKEKSSTA 2438
Query: 256 -----TCVVRINTELPAIDNSY---LNQLNELKETVKQFDDLSVYILN--DSSKQTSIEI 305
T + +N + A+ N + L V+ + +L D +K I +
Sbjct: 2439 MEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVL 2498
Query: 306 EQ-LNARVVEAET------KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI-KK 357
+ +N + E E K E++R+K ++Q Q +L V+ + ++ + + K+
Sbjct: 2499 QSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQ-EQL-----VSKLSQVEGEHQLWKE 2552
Query: 358 QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ 417
Q+L+L + E+++++QV + Q ++ L + + E K S ++
Sbjct: 2553 QNLELRNLTV---ELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK 2609
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELA----IVAADYDEITKELRIADERYQRV--- 470
+ + EL ++ A++++EL+ +A + + +E++ + ++ + +
Sbjct: 2610 VNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLE 2669
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
+ELK +++ +H++Q +E K E E+ +RL E E K+ + L
Sbjct: 2670 NSELKKSLDCMHKDQ-----VEKEGKVRE-EIAEYQLRLHEAE-------KKHQALLLDT 2716
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL-----LQDSLEKTSQ 585
K E+E+ + + + L ++ ++ +++ +++ N SL + + L+KT
Sbjct: 2717 NKQYEVEIQTYREKLTSKEECLSSQKLEID--LLKSSKEELNNSLKATTQILEELKKTKM 2774
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTST 644
Y QL ++ +Q + + + ++LE ++ S L + K +T T
Sbjct: 2775 DNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDT 2833
Score = 39.5 bits (88), Expect = 0.037
Identities = 62/348 (17%), Positives = 153/348 (43%), Gaps = 47/348 (13%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
+NDS K+ +++E +R+ + ++ E ++ L++ TE +L L+ K N + QK
Sbjct: 1888 VNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTE-KLCLE---KDNENKQK 1943
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
I +L+ + + ++++ +L + + + + + +E+ + + L +
Sbjct: 1944 VIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQV 2003
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
E + +E + L+ L K ++++L + D ++ + E
Sbjct: 2004 AEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSL-----------TKCE 2052
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
L++ + L++E+E +VK E +++ RL E + + + LEA +
Sbjct: 2053 LENQIAQLNKEKELLVK----------ESESLQARLSESDYEKL----NVSKALEAAL-- 2096
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
+E E R + T + + + R ++++ ++ E D+K +++ I ++
Sbjct: 2097 --VEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEK-------------KQLHIAEK- 2140
Query: 594 LAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
L E+E + +V +REL+ +E+ ++ + +A+ T T
Sbjct: 2141 LKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKT 2188
Score = 33.9 bits (74), Expect = 1.8
Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 5/137 (3%)
Query: 472 TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI 531
T LK + L E E + K + K S E++VK V +E + N+ GK+ I KLE +
Sbjct: 63 TNLKRENQRLMEICESLEKTKQ-KISHELQVKESQVNFQEGQLNS---GKKQIEKLEQEL 118
Query: 532 KDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQ-KNISLLQDSLEKTSQKVSIY 590
K + EL+ ++ L K Q + S +D EK +++V
Sbjct: 119 KRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEER 178
Query: 591 KRQLAEQEGMSQQSVTR 607
KR AE + + + ++
Sbjct: 179 KRLEAEVKALQAKKASQ 195
Score = 33.5 bits (73), Expect = 2.4
Identities = 37/161 (22%), Positives = 72/161 (44%), Gaps = 14/161 (8%)
Query: 300 QTSIEIEQLNARVVEAETKLK-SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
+T E + L + + K + SE + K Q+ + E+SLD N + L+ ++ +
Sbjct: 1160 KTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNK 1219
Query: 359 SLQLTEIQTHYDEVQRQLQV---TLDQYGVAQRRIQSLTG------EVEE--IRGNYEQA 407
L+L E + + +Q +LQ L+ + + Q ++G + EE I G +E +
Sbjct: 1220 ELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELS 1279
Query: 408 LRVKRSVEQQ--YEESQTRVNELTVINVNLSSSKAKIEQEL 446
+ Q + + ++NEL I L + K ++ EL
Sbjct: 1280 TSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTEL 1320
Score = 33.1 bits (72), Expect = 3.2
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Query: 524 ISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ LEA + +++ EK L+++ ++L E+ CE +K + L+
Sbjct: 41 LDSLEAAPQKQTQKVENEKTEGTN----LKRENQRLMEI---CESLEKTKQKISHELQVK 93
Query: 584 SQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTS 643
+V+ + QL + ++ ++R + ELE ++ A A+ +L+ + F TT
Sbjct: 94 ESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIF-TTP 152
Query: 644 TVPGSQVY 651
P SQ Y
Sbjct: 153 LTP-SQYY 159
>AL832010-1|CAD89917.1| 973|Homo sapiens hypothetical protein
protein.
Length = 973
Score = 59.3 bits (137), Expect = 4e-08
Identities = 70/327 (21%), Positives = 146/327 (44%), Gaps = 15/327 (4%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+E + VK+ + + + SS++ E E + +E + + + ++ +Q+ E
Sbjct: 622 HEFTKLVKELEGVITKAIYKSSEEDKKEEEV--KKTLEQHDDIVTHYKNMIREQDLQLEE 679
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
L + N LQ + +Q Q+ + + Y+ ++ QL G Q +
Sbjct: 680 LRQQVSTLKCQNEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQ 739
Query: 397 VEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEI 456
EEI E+ +KR+ Q+ +SQ + + N+ S + EQ AIV+A E
Sbjct: 740 PEEIGRLREEIEELKRN--QELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQ 797
Query: 457 TKELR--IADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKN---ISVRLEE 511
EL+ +A + Q + ++ + E+QE + K EA KS+E++ + I+ + +
Sbjct: 798 VAELKQELATLKSQ-LNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTD 856
Query: 512 VEA--NAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
VE +A++ + + + + + E+ TI IL+ ++ +L+ I +++
Sbjct: 857 VEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKE 916
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAE 596
Q ++ +L L QK+ K +L +
Sbjct: 917 QDDLLVL---LADQDQKILSLKNKLKD 940
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 59.3 bits (137), Expect = 4e-08
Identities = 83/477 (17%), Positives = 206/477 (43%), Gaps = 31/477 (6%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEES----RRNVQNERM 198
+ ++ ++ KE +L KE ++ + +KA+ L+E+ R + E +
Sbjct: 2055 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEV 2114
Query: 199 YKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCV 258
++ + V + + +A+ L E + N E++ +++ E + +
Sbjct: 2115 HQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVI 2174
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+ ++ + Q+ E+ ++K F+ L + L + + +I++ ++ E +
Sbjct: 2175 LDAENSKAEVE-TLKTQIEEMARSLKVFE-LDLVTLRSEKENLTKQIQEKQGQLSELDKL 2232
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L S + +++K Q +I E S KT +++ + K+ + E+ + +
Sbjct: 2233 LSSFKSLLEEKEQAEIQIKEES-----KTAVEMLQNQLKELNEAVAALCGDQEIMKATEQ 2287
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-----------E 427
+LD + ++++ +E++R E + + V QQ +ES+ + E
Sbjct: 2288 SLDPPIEEEHQLRN---SIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERE 2344
Query: 428 LTVINVNLSSSKAKIEQ---ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
L + N + + E E+ + A + +T+ LR + +++E ++ L +E
Sbjct: 2345 LEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKE 2404
Query: 485 QERIVKIEAVKKSLE---IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE 541
QERI ++E + S E E + V+++E + A+ + + +L R+ + + +
Sbjct: 2405 QERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEAC 2464
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
K + + E + +++ +E + N +LQ S+ Q+V K++L +++
Sbjct: 2465 KAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKD 2521
Score = 57.2 bits (132), Expect = 2e-07
Identities = 98/441 (22%), Positives = 197/441 (44%), Gaps = 34/441 (7%)
Query: 219 KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSY--LNQL 276
K + + LM+++ M+ S V E+ +++E + V T L A++N L L
Sbjct: 860 KGEIEENLMKAEQMHQ--SFVAETSQRISKLQEDTSAHQNVVAET-LSALENKEKELQLL 916
Query: 277 NELKETVK-QFDDL--SVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N+ ET + + +L S ++L DS K+ QL + + E K S + + K+ +
Sbjct: 917 NDKVETEQAEIQELKKSNHLLEDSLKEL-----QLLSETLSLEKKEMSSIISLNKR---E 968
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY-DEVQRQLQVTLDQYGVAQRRIQS 392
I EL + N L + K +Q +E +Y DE ++ + DQY Q ++
Sbjct: 969 IEELTQENGTLKEINASLNQE-KMNLIQKSESFANYIDEREKSISELSDQY--KQEKL-I 1024
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
L EE YE + ++ +++ + + +NE T + N K ++EQ A +
Sbjct: 1025 LLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCEN---RKNELEQLKEAFAKE 1081
Query: 453 YDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
+ E +L A+ER Q + EL+ + L E + + KS +K + L+E
Sbjct: 1082 HQEFLTKLAFAEERNQNLMLELETVQQALRSE---MTDNQNNSKSEAGGLKQEIMTLKE- 1137
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCE-EDQK 571
E N + K + L+ + M++ + + ++ E+ + +R ++ + QC + Q
Sbjct: 1138 EQNKM--QKEVNDLLQENEQLMKVMKTKHECQNLES-EPIRNSVKERESERNQCNFKPQM 1194
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ + + SL+ + ++ + L +E Q+S Q EL+ R D+ SNL
Sbjct: 1195 DLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTI--RGDLETSNLQD 1252
Query: 632 IRAKHRTFVTTSTVPGSQVYL 652
++++ + + + + Y+
Sbjct: 1253 MQSQEISGLKDCEIDAEEKYI 1273
Score = 56.4 bits (130), Expect = 3e-07
Identities = 57/346 (16%), Positives = 145/346 (41%), Gaps = 25/346 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQI 332
N+L+ ++ + ++Y+ + +E+ Q +E + + K +V ++++L +
Sbjct: 1902 NELSRIRSEKASIEHEALYL------EADLEVVQTEKLCLEKDNENKQKVIVCLEEELSV 1955
Query: 333 QITE---LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
+E L LD +K L + +K + E+++H E +QV +
Sbjct: 1956 VTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTEL 2015
Query: 390 IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIV 449
+Q+L+ +V E+ L+ K ++++ + + L++ L + A++ +E ++
Sbjct: 2016 LQTLSSDVSEL-------LKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELL 2068
Query: 450 AADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRL 509
+ + + L +D V L+ + E R+ + L ++ + VR+
Sbjct: 2069 VKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRI 2128
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
E E + + ++K+ E E D K + + L+ E + VI+ E
Sbjct: 2129 EADEKKQL--------HIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENS 2180
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ + L+ +E+ ++ + +++ L + +++ Q +L
Sbjct: 2181 KAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQL 2226
Score = 54.4 bits (125), Expect = 1e-06
Identities = 95/494 (19%), Positives = 215/494 (43%), Gaps = 41/494 (8%)
Query: 152 ELDLY----EKEVNLGSELRQKAAMYRGKSAKAIA--QTLLEESRRNVQNERMYKPDFQA 205
ELDL EKE NL ++++K + K ++ ++LLEE Q E K + +
Sbjct: 2202 ELDLVTLRSEKE-NLTKQIQEKQGQL-SELDKLLSSFKSLLEEKE---QAEIQIKEESKT 2256
Query: 206 SRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTEL 265
+ ++ L++ V A + + M + + + I E ++R + + ++ L
Sbjct: 2257 AVEMLQNQLKELNEAVAALC-GDQEIMKATEQSLDPPIEEEHQLRNS-----IEKLRARL 2310
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNAR--VVEAETKLKSEV 323
A + L L +LKE+ D L + N + +EI + N +EAE K EV
Sbjct: 2311 EADEKKQLCVLQQLKESEHHADLLKGRVEN---LERELEIARTNQEHAALEAENS-KGEV 2366
Query: 324 TRIKKKLQIQITELE-LSLDV----ANKTNI--DLQKTIKKQSLQLTEIQTHYDEV-QRQ 375
+K K++ L L LDV + K N+ +LQK ++ S +L I + ++ + Q +
Sbjct: 2367 ETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERIS-ELEIINSSFENILQEK 2425
Query: 376 LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
Q + + ++ L +++E+ + + + + + ++V L + L
Sbjct: 2426 EQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQL 2485
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ + ++ + + + +E+ ++ ++ E+ + ++++ + K+ V+
Sbjct: 2486 LQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVE 2545
Query: 496 ------KSLEIEVKNISVRLEE---VEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
K +E++N++V LE+ V + + + L++ K++E EL+ K
Sbjct: 2546 GEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKM 2605
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
++ + K + E+ + E + + LQ+ L +++ + L E+ S+ +
Sbjct: 2606 SFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLK 2665
Query: 607 RVRRFQRELEAAED 620
+ EL+ + D
Sbjct: 2666 ELTLENSELKKSLD 2679
Score = 50.4 bits (115), Expect = 2e-05
Identities = 67/383 (17%), Positives = 174/383 (45%), Gaps = 27/383 (7%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ T++ + + +++N L ET + + + N+ + ++ E L+ + L
Sbjct: 628 KLLTQMESEKENLQSKINHL-ETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
S+ ++ + ++ EL+ + +++ + QK I+ L+ +++ ++++ +LQ+
Sbjct: 687 DSKSVEVETQ-KLAYMELQQKAEFSDQKH---QKEIENMCLKTSQLTGQVEDLEHKLQLL 742
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN---VNLS 436
++ R Q L E E +R + ++ + ++ S ++ ++ N+
Sbjct: 743 SNEIMDKDRCYQDLHAEYESLR-DLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANII 801
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKK 496
+ + E + + D+ K I R ++ L+ + + Q++ ++ +K
Sbjct: 802 GEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKG 861
Query: 497 SLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKE 556
+E +N+ ++ E++ + + + ISKL+ + + AET+ L KE
Sbjct: 862 EIE---ENL-MKAEQMHQSFVAETSQRISKLQE-------DTSAHQNVVAETLSALENKE 910
Query: 557 RQLKEVIIQCEEDQKNISLLQDS---LEKTSQKVSIYKRQLA-EQEGMSQQSVTRVRRFQ 612
++L+ + + E +Q I L+ S LE + +++ + L+ E++ MS S+ + + +
Sbjct: 911 KELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMS--SIISLNKRE 968
Query: 613 RELEAAEDRADVAESNLSLIRAK 635
E E ++ + E N SL + K
Sbjct: 969 IE-ELTQENGTLKEINASLNQEK 990
Score = 48.4 bits (110), Expect = 8e-05
Identities = 73/347 (21%), Positives = 152/347 (43%), Gaps = 21/347 (6%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+EL T Q+D S K + E L+ + AE+ S +IK+K + + E
Sbjct: 341 DELVRTTAQYDQASTKYTALEQKLKKLT-EDLSCQRQNAESARCSLEQKIKEK-EKEFQE 398
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
ELS + +D Q+ I+ ++ E+Q + LQ LD+ ++++++ E
Sbjct: 399 -ELSRQQRSFQTLD-QECIQMKARLTQELQ-QAKNMHNVLQAELDKLTSVKQQLENNLEE 455
Query: 397 VEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEI 456
++ EQA + + E + S + E+ N L S + +E+ + A+ I
Sbjct: 456 FKQKLCRAEQAFQASQIKENELRRS---MEEMKKENNLLKSHSEQKAREVCHLEAELKNI 512
Query: 457 TKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANA 516
+ L + + ++ + L + QE KI + SL +E ++V E + +
Sbjct: 513 KQCLNQSQNFAEEMKAKNTSQETMLRDLQE---KINQQENSLTLEKLKLAVADLEKQRDC 569
Query: 517 IVGGKRIISKLEARIKDMELEL---DEEKRRHAETIKILRKKERQLKE--VIIQC--EED 569
+ ++ K E I+ + +L ++E + +++ +K+ +LKE + C E+
Sbjct: 570 ---SQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSEN 626
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+K ++ ++ E K++ + L Q+ S + RVR + + E
Sbjct: 627 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRE 673
Score = 46.8 bits (106), Expect = 2e-04
Identities = 70/319 (21%), Positives = 140/319 (43%), Gaps = 13/319 (4%)
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAETKLKSE 322
L + +SY N NEL+ T + ++K+T + E+ ++ + E + +L E
Sbjct: 2583 LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGE 2642
Query: 323 VTRIKKKLQIQITELELSLDVANKT---NIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
R+ +LQ+ + E++ S D + N +L+K++ E + E + Q+
Sbjct: 2643 KNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR 2702
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVNLSSS 438
L + A+++ Q+L + + Q R K + +++ SQ ++ L L++S
Sbjct: 2703 LHE---AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNS 2759
Query: 439 -KA--KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
KA +I +EL D + +L+ +ER Q L + + L EE+E + K +
Sbjct: 2760 LKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQL 2819
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
++ + + K +V +V+ K + LE + K+ + LD+ K+ + K
Sbjct: 2820 QAAQEKQKTGTVMDTKVD-ELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAK 2878
Query: 556 ERQLKEVIIQCEEDQKNIS 574
E +V C + K S
Sbjct: 2879 EMLETQVAHLCSQQSKQDS 2897
Score = 45.6 bits (103), Expect = 6e-04
Identities = 70/364 (19%), Positives = 164/364 (45%), Gaps = 40/364 (10%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L +++ +I +L R+ E ++K +V + ++ LQ+Q+ + ++ L I+ +K
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQE-LQLQLEKAKVEL-------IEKEK 334
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-----L 408
+ K +L YD+ +Y +++++ LT ++ R N E A
Sbjct: 335 VLNKCRDELVRTTAQYDQAS-------TKYTALEQKLKKLTEDLSCQRQNAESARCSLEQ 387
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQ 468
++K ++ EE + ++ KA++ QEL ++ + EL ++
Sbjct: 388 KIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL----DKLT 443
Query: 469 RVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV--EANAIVGGK----R 522
V+ +L++ +E E ++++ + E ++ +I+ + +EE+ E N + R
Sbjct: 444 SVKQQLENNLE---EFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAR 500
Query: 523 IISKLEARIKDMELELDEEKRRHAETIKILR-KKERQLKEVIIQCEEDQKNISLLQDSLE 581
+ LEA +K+++ L+ + + AE +K +E L++ +Q + +Q+ SL +LE
Sbjct: 501 EVCHLEAELKNIKQCLN-QSQNFAEEMKAKNTSQETMLRD--LQEKINQQENSL---TLE 554
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
K V+ ++Q + + ++ + + +L E + S L L + ++
Sbjct: 555 KLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKE 614
Query: 642 TSTV 645
T+
Sbjct: 615 EKTL 618
Score = 45.2 bits (102), Expect = 7e-04
Identities = 105/539 (19%), Positives = 232/539 (43%), Gaps = 64/539 (11%)
Query: 144 KRMQEIEKELDLYEKEV-NLGSELR-----QKAAMYRGKSAKAIAQTLLEESRRNVQNER 197
++++E E DL + V NL EL Q+ A +++K +TL + Q+ R
Sbjct: 2322 QQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLR 2381
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSC-DSRVTESITETVRVRETSPT- 255
+ D R+ L K + + E + +NS ++ + E E V+++E S T
Sbjct: 2382 GLELDVVTIRSEKENLTNELQKE--QERISELEIINSSFENILQEKEQEKVQMKEKSSTA 2439
Query: 256 -----TCVVRINTELPAIDNSY---LNQLNELKETVKQFDDLSVYILN--DSSKQTSIEI 305
T + +N + A+ N + L V+ + +L D +K I +
Sbjct: 2440 MEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVL 2499
Query: 306 EQ-LNARVVEAET------KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI-KK 357
+ +N + E E K E++R+K ++Q Q +L V+ + ++ + + K+
Sbjct: 2500 QSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQ-EQL-----VSKLSQVEGEHQLWKE 2553
Query: 358 QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ 417
Q+L+L + E+++++QV + Q ++ L + + E K S ++
Sbjct: 2554 QNLELRNLTV---ELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK 2610
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELA----IVAADYDEITKELRIADERYQRV--- 470
+ + EL ++ A++++EL+ +A + + +E++ + ++ + +
Sbjct: 2611 VNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLE 2670
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
+ELK +++ +H++Q +E K E E+ +RL E E K+ + L
Sbjct: 2671 NSELKKSLDCMHKDQ-----VEKEGKVRE-EIAEYQLRLHEAE-------KKHQALLLDT 2717
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL-----LQDSLEKTSQ 585
K E+E+ + + + L ++ ++ +++ +++ N SL + + L+KT
Sbjct: 2718 NKQYEVEIQTYREKLTSKEECLSSQKLEID--LLKSSKEELNNSLKATTQILEELKKTKM 2775
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTST 644
Y QL ++ +Q + + + ++LE ++ S L + K +T T
Sbjct: 2776 DNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDT 2834
Score = 39.5 bits (88), Expect = 0.037
Identities = 62/348 (17%), Positives = 153/348 (43%), Gaps = 47/348 (13%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
+NDS K+ +++E +R+ + ++ E ++ L++ TE +L L+ K N + QK
Sbjct: 1889 VNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTE-KLCLE---KDNENKQK 1944
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
I +L+ + + ++++ +L + + + + + +E+ + + L +
Sbjct: 1945 VIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQV 2004
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
E + +E + L+ L K ++++L + D ++ + E
Sbjct: 2005 AEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSL-----------TKCE 2053
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
L++ + L++E+E +VK E +++ RL E + + + LEA +
Sbjct: 2054 LENQIAQLNKEKELLVK----------ESESLQARLSESDYEKL----NVSKALEAAL-- 2097
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
+E E R + T + + + R ++++ ++ E D+K +++ I ++
Sbjct: 2098 --VEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEK-------------KQLHIAEK- 2141
Query: 594 LAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
L E+E + +V +REL+ +E+ ++ + +A+ T T
Sbjct: 2142 LKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKT 2189
Score = 35.9 bits (79), Expect = 0.46
Identities = 29/128 (22%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Query: 524 ISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ LEA ++ + +++ EK L+++ ++L E+ CE +K + L+
Sbjct: 41 LDSLEAALQKQKQKVENEKTEGTN----LKRENQRLMEI---CESLEKTKQKISHELQVK 93
Query: 584 SQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTS 643
+V+ + QL + ++ ++R + ELE ++ A A+ +L+ + F TT
Sbjct: 94 ESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIF-TTP 152
Query: 644 TVPGSQVY 651
P SQ Y
Sbjct: 153 LTP-SQYY 159
Score = 33.9 bits (74), Expect = 1.8
Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 5/137 (3%)
Query: 472 TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI 531
T LK + L E E + K + K S E++VK V +E + N+ GK+ I KLE +
Sbjct: 63 TNLKRENQRLMEICESLEKTKQ-KISHELQVKESQVNFQEGQLNS---GKKQIEKLEQEL 118
Query: 532 KDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQ-KNISLLQDSLEKTSQKVSIY 590
K + EL+ ++ L K Q + S +D EK +++V
Sbjct: 119 KRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEER 178
Query: 591 KRQLAEQEGMSQQSVTR 607
KR AE + + + ++
Sbjct: 179 KRLEAEVKALQAKKASQ 195
Score = 33.5 bits (73), Expect = 2.4
Identities = 37/161 (22%), Positives = 72/161 (44%), Gaps = 14/161 (8%)
Query: 300 QTSIEIEQLNARVVEAETKLK-SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
+T E + L + + K + SE + K Q+ + E+SLD N + L+ ++ +
Sbjct: 1161 KTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNK 1220
Query: 359 SLQLTEIQTHYDEVQRQLQV---TLDQYGVAQRRIQSLTG------EVEE--IRGNYEQA 407
L+L E + + +Q +LQ L+ + + Q ++G + EE I G +E +
Sbjct: 1221 ELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELS 1280
Query: 408 LRVKRSVEQQ--YEESQTRVNELTVINVNLSSSKAKIEQEL 446
+ Q + + ++NEL I L + K ++ EL
Sbjct: 1281 TSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTEL 1321
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 59.3 bits (137), Expect = 4e-08
Identities = 83/477 (17%), Positives = 206/477 (43%), Gaps = 31/477 (6%)
Query: 143 KKRMQEIEKELDLYEKEVNLGSELRQKAAMYRGKSAKAIAQTLLEES----RRNVQNERM 198
+ ++ ++ KE +L KE ++ + +KA+ L+E+ R + E +
Sbjct: 2055 ENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEV 2114
Query: 199 YKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCV 258
++ + V + + +A+ L E + N E++ +++ E + +
Sbjct: 2115 HQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVI 2174
Query: 259 VRINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETK 318
+ ++ + Q+ E+ ++K F+ L + L + + +I++ ++ E +
Sbjct: 2175 LDAENSKAEVE-TLKTQIEEMARSLKVFE-LDLVTLRSEKENLTKQIQEKQGQLSELDKL 2232
Query: 319 LKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQV 378
L S + +++K Q +I E S KT +++ + K+ + E+ + +
Sbjct: 2233 LSSFKSLLEEKEQAEIQIKEES-----KTAVEMLQNQLKELNEAVAALCGDQEIMKATEQ 2287
Query: 379 TLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVN-----------E 427
+LD + ++++ +E++R E + + V QQ +ES+ + E
Sbjct: 2288 SLDPPIEEEHQLRN---SIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERE 2344
Query: 428 LTVINVNLSSSKAKIEQ---ELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEE 484
L + N + + E E+ + A + +T+ LR + +++E ++ L +E
Sbjct: 2345 LEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKE 2404
Query: 485 QERIVKIEAVKKSLE---IEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEE 541
QERI ++E + S E E + V+++E + A+ + + +L R+ + + +
Sbjct: 2405 QERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEAC 2464
Query: 542 KRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQE 598
K + + E + +++ +E + N +LQ S+ Q+V K++L +++
Sbjct: 2465 KAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKD 2521
Score = 57.2 bits (132), Expect = 2e-07
Identities = 98/441 (22%), Positives = 197/441 (44%), Gaps = 34/441 (7%)
Query: 219 KNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTELPAIDNSY--LNQL 276
K + + LM+++ M+ S V E+ +++E + V T L A++N L L
Sbjct: 860 KGEIEENLMKAEQMHQ--SFVAETSQRISKLQEDTSAHQNVVAET-LSALENKEKELQLL 916
Query: 277 NELKETVK-QFDDL--SVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQ 333
N+ ET + + +L S ++L DS K+ QL + + E K S + + K+ +
Sbjct: 917 NDKVETEQAEIQELKKSNHLLEDSLKEL-----QLLSETLSLEKKEMSSIISLNKR---E 968
Query: 334 ITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHY-DEVQRQLQVTLDQYGVAQRRIQS 392
I EL + N L + K +Q +E +Y DE ++ + DQY Q ++
Sbjct: 969 IEELTQENGTLKEINASLNQE-KMNLIQKSESFANYIDEREKSISELSDQY--KQEKL-I 1024
Query: 393 LTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAAD 452
L EE YE + ++ +++ + + +NE T + N K ++EQ A +
Sbjct: 1025 LLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCEN---RKNELEQLKEAFAKE 1081
Query: 453 YDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV 512
+ E +L A+ER Q + EL+ + L E + + KS +K + L+E
Sbjct: 1082 HQEFLTKLAFAEERNQNLMLELETVQQALRSE---MTDNQNNSKSEAGGLKQEIMTLKE- 1137
Query: 513 EANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCE-EDQK 571
E N + K + L+ + M++ + + ++ E+ + +R ++ + QC + Q
Sbjct: 1138 EQNKM--QKEVNDLLQENEQLMKVMKTKHECQNLES-EPIRNSVKERESERNQCNFKPQM 1194
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSL 631
++ + + SL+ + ++ + L +E Q+S Q EL+ R D+ SNL
Sbjct: 1195 DLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTI--RGDLETSNLQD 1252
Query: 632 IRAKHRTFVTTSTVPGSQVYL 652
++++ + + + + Y+
Sbjct: 1253 MQSQEISGLKDCEIDAEEKYI 1273
Score = 56.4 bits (130), Expect = 3e-07
Identities = 57/346 (16%), Positives = 145/346 (41%), Gaps = 25/346 (7%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEV-TRIKKKLQI 332
N+L+ ++ + ++Y+ + +E+ Q +E + + K +V ++++L +
Sbjct: 1902 NELSRIRSEKASIEHEALYL------EADLEVVQTEKLCLEKDNENKQKVIVCLEEELSV 1955
Query: 333 QITE---LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRR 389
+E L LD +K L + +K + E+++H E +QV +
Sbjct: 1956 VTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTEL 2015
Query: 390 IQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIV 449
+Q+L+ +V E+ L+ K ++++ + + L++ L + A++ +E ++
Sbjct: 2016 LQTLSSDVSEL-------LKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELL 2068
Query: 450 AADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRL 509
+ + + L +D V L+ + E R+ + L ++ + VR+
Sbjct: 2069 VKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRI 2128
Query: 510 EEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEED 569
E E + + ++K+ E E D K + + L+ E + VI+ E
Sbjct: 2129 EADEKKQL--------HIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENS 2180
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQREL 615
+ + L+ +E+ ++ + +++ L + +++ Q +L
Sbjct: 2181 KAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQL 2226
Score = 54.4 bits (125), Expect = 1e-06
Identities = 95/494 (19%), Positives = 215/494 (43%), Gaps = 41/494 (8%)
Query: 152 ELDLY----EKEVNLGSELRQKAAMYRGKSAKAIA--QTLLEESRRNVQNERMYKPDFQA 205
ELDL EKE NL ++++K + K ++ ++LLEE Q E K + +
Sbjct: 2202 ELDLVTLRSEKE-NLTKQIQEKQGQL-SELDKLLSSFKSLLEEKE---QAEIQIKEESKT 2256
Query: 206 SRTLVNRDYTNLSKNVLAKALMESKAMNSCDSRVTESITETVRVRETSPTTCVVRINTEL 265
+ ++ L++ V A + + M + + + I E ++R + + ++ L
Sbjct: 2257 AVEMLQNQLKELNEAVAALC-GDQEIMKATEQSLDPPIEEEHQLRNS-----IEKLRARL 2310
Query: 266 PAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNAR--VVEAETKLKSEV 323
A + L L +LKE+ D L + N + +EI + N +EAE K EV
Sbjct: 2311 EADEKKQLCVLQQLKESEHHADLLKGRVEN---LERELEIARTNQEHAALEAENS-KGEV 2366
Query: 324 TRIKKKLQIQITELE-LSLDV----ANKTNI--DLQKTIKKQSLQLTEIQTHYDEV-QRQ 375
+K K++ L L LDV + K N+ +LQK ++ S +L I + ++ + Q +
Sbjct: 2367 ETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERIS-ELEIINSSFENILQEK 2425
Query: 376 LQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNL 435
Q + + ++ L +++E+ + + + + + ++V L + L
Sbjct: 2426 EQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQL 2485
Query: 436 SSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
+ + ++ + + + +E+ ++ ++ E+ + ++++ + K+ V+
Sbjct: 2486 LQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVE 2545
Query: 496 ------KSLEIEVKNISVRLEE---VEANAIVGGKRIISKLEARIKDMELELDEEKRRHA 546
K +E++N++V LE+ V + + + L++ K++E EL+ K
Sbjct: 2546 GEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKM 2605
Query: 547 ETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVT 606
++ + K + E+ + E + + LQ+ L +++ + L E+ S+ +
Sbjct: 2606 SFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLK 2665
Query: 607 RVRRFQRELEAAED 620
+ EL+ + D
Sbjct: 2666 ELTLENSELKKSLD 2679
Score = 50.4 bits (115), Expect = 2e-05
Identities = 67/383 (17%), Positives = 174/383 (45%), Gaps = 27/383 (7%)
Query: 260 RINTELPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKL 319
++ T++ + + +++N L ET + + + N+ + ++ E L+ + L
Sbjct: 628 KLLTQMESEKENLQSKINHL-ETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686
Query: 320 KSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
S+ ++ + ++ EL+ + +++ + QK I+ L+ +++ ++++ +LQ+
Sbjct: 687 DSKSVEVETQ-KLAYMELQQKAEFSDQKH---QKEIENMCLKTSQLTGQVEDLEHKLQLL 742
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVIN---VNLS 436
++ R Q L E E +R + ++ + ++ S ++ ++ N+
Sbjct: 743 SNEIMDKDRCYQDLHAEYESLR-DLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANII 801
Query: 437 SSKAKIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKK 496
+ + E + + D+ K I R ++ L+ + + Q++ ++ +K
Sbjct: 802 GEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKG 861
Query: 497 SLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKE 556
+E +N+ ++ E++ + + + ISKL+ + + AET+ L KE
Sbjct: 862 EIE---ENL-MKAEQMHQSFVAETSQRISKLQE-------DTSAHQNVVAETLSALENKE 910
Query: 557 RQLKEVIIQCEEDQKNISLLQDS---LEKTSQKVSIYKRQLA-EQEGMSQQSVTRVRRFQ 612
++L+ + + E +Q I L+ S LE + +++ + L+ E++ MS S+ + + +
Sbjct: 911 KELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMS--SIISLNKRE 968
Query: 613 RELEAAEDRADVAESNLSLIRAK 635
E E ++ + E N SL + K
Sbjct: 969 IE-ELTQENGTLKEINASLNQEK 990
Score = 48.4 bits (110), Expect = 8e-05
Identities = 73/347 (21%), Positives = 152/347 (43%), Gaps = 21/347 (6%)
Query: 277 NELKETVKQFDDLSVYILNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITE 336
+EL T Q+D S K + E L+ + AE+ S +IK+K + + E
Sbjct: 341 DELVRTTAQYDQASTKYTALEQKLKKLT-EDLSCQRQNAESARCSLEQKIKEK-EKEFQE 398
Query: 337 LELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGE 396
ELS + +D Q+ I+ ++ E+Q + LQ LD+ ++++++ E
Sbjct: 399 -ELSRQQRSFQTLD-QECIQMKARLTQELQ-QAKNMHNVLQAELDKLTSVKQQLENNLEE 455
Query: 397 VEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEI 456
++ EQA + + E + S + E+ N L S + +E+ + A+ I
Sbjct: 456 FKQKLCRAEQAFQASQIKENELRRS---MEEMKKENNLLKSHSEQKAREVCHLEAELKNI 512
Query: 457 TKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANA 516
+ L + + ++ + L + QE KI + SL +E ++V E + +
Sbjct: 513 KQCLNQSQNFAEEMKAKNTSQETMLRDLQE---KINQQENSLTLEKLKLAVADLEKQRDC 569
Query: 517 IVGGKRIISKLEARIKDMELEL---DEEKRRHAETIKILRKKERQLKE--VIIQC--EED 569
+ ++ K E I+ + +L ++E + +++ +K+ +LKE + C E+
Sbjct: 570 ---SQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSEN 626
Query: 570 QKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELE 616
+K ++ ++ E K++ + L Q+ S + RVR + + E
Sbjct: 627 EKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRE 673
Score = 46.8 bits (106), Expect = 2e-04
Identities = 70/319 (21%), Positives = 140/319 (43%), Gaps = 13/319 (4%)
Query: 265 LPAIDNSYLNQLNELKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAETKLKSE 322
L + +SY N NEL+ T + ++K+T + E+ ++ + E + +L E
Sbjct: 2583 LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGE 2642
Query: 323 VTRIKKKLQIQITELELSLDVANKT---NIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVT 379
R+ +LQ+ + E++ S D + N +L+K++ E + E + Q+
Sbjct: 2643 KNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLR 2702
Query: 380 LDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQT-RVNELTVINVNLSSS 438
L + A+++ Q+L + + Q R K + +++ SQ ++ L L++S
Sbjct: 2703 LHE---AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNS 2759
Query: 439 -KA--KIEQELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVK 495
KA +I +EL D + +L+ +ER Q L + + L EE+E + K +
Sbjct: 2760 LKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQL 2819
Query: 496 KSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKK 555
++ + + K +V +V+ K + LE + K+ + LD+ K+ + K
Sbjct: 2820 QAAQEKQKTGTVMDTKVD-ELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAK 2878
Query: 556 ERQLKEVIIQCEEDQKNIS 574
E +V C + K S
Sbjct: 2879 EMLETQVAHLCSQQSKQDS 2897
Score = 45.6 bits (103), Expect = 6e-04
Identities = 70/364 (19%), Positives = 164/364 (45%), Gaps = 40/364 (10%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
L +++ +I +L R+ E ++K +V + ++ LQ+Q+ + ++ L I+ +K
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQE-LQLQLEKAKVEL-------IEKEK 334
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-----L 408
+ K +L YD+ +Y +++++ LT ++ R N E A
Sbjct: 335 VLNKCRDELVRTTAQYDQAS-------TKYTALEQKLKKLTEDLSCQRQNAESARCSLEQ 387
Query: 409 RVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQ 468
++K ++ EE + ++ KA++ QEL ++ + EL ++
Sbjct: 388 KIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL----DKLT 443
Query: 469 RVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEV--EANAIVGGK----R 522
V+ +L++ +E E ++++ + E ++ +I+ + +EE+ E N + R
Sbjct: 444 SVKQQLENNLE---EFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAR 500
Query: 523 IISKLEARIKDMELELDEEKRRHAETIKILR-KKERQLKEVIIQCEEDQKNISLLQDSLE 581
+ LEA +K+++ L+ + + AE +K +E L++ +Q + +Q+ SL +LE
Sbjct: 501 EVCHLEAELKNIKQCLN-QSQNFAEEMKAKNTSQETMLRD--LQEKINQQENSL---TLE 554
Query: 582 KTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
K V+ ++Q + + ++ + + +L E + S L L + ++
Sbjct: 555 KLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKE 614
Query: 642 TSTV 645
T+
Sbjct: 615 EKTL 618
Score = 45.2 bits (102), Expect = 7e-04
Identities = 105/539 (19%), Positives = 232/539 (43%), Gaps = 64/539 (11%)
Query: 144 KRMQEIEKELDLYEKEV-NLGSELR-----QKAAMYRGKSAKAIAQTLLEESRRNVQNER 197
++++E E DL + V NL EL Q+ A +++K +TL + Q+ R
Sbjct: 2322 QQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLR 2381
Query: 198 MYKPDFQASRTLVNRDYTNLSKNVLAKALMESKAMNSC-DSRVTESITETVRVRETSPT- 255
+ D R+ L K + + E + +NS ++ + E E V+++E S T
Sbjct: 2382 GLELDVVTIRSEKENLTNELQKE--QERISELEIINSSFENILQEKEQEKVQMKEKSSTA 2439
Query: 256 -----TCVVRINTELPAIDNSY---LNQLNELKETVKQFDDLSVYILN--DSSKQTSIEI 305
T + +N + A+ N + L V+ + +L D +K I +
Sbjct: 2440 MEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVL 2499
Query: 306 EQ-LNARVVEAET------KLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQKTI-KK 357
+ +N + E E K E++R+K ++Q Q +L V+ + ++ + + K+
Sbjct: 2500 QSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQ-EQL-----VSKLSQVEGEHQLWKE 2553
Query: 358 QSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQ 417
Q+L+L + E+++++QV + Q ++ L + + E K S ++
Sbjct: 2554 QNLELRNLTV---ELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK 2610
Query: 418 YEESQTRVNELTVINVNLSSSKAKIEQELA----IVAADYDEITKELRIADERYQRV--- 470
+ + EL ++ A++++EL+ +A + + +E++ + ++ + +
Sbjct: 2611 VNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLE 2670
Query: 471 QTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEAR 530
+ELK +++ +H++Q +E K E E+ +RL E E K+ + L
Sbjct: 2671 NSELKKSLDCMHKDQ-----VEKEGKVRE-EIAEYQLRLHEAE-------KKHQALLLDT 2717
Query: 531 IKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISL-----LQDSLEKTSQ 585
K E+E+ + + + L ++ ++ +++ +++ N SL + + L+KT
Sbjct: 2718 NKQYEVEIQTYREKLTSKEECLSSQKLEID--LLKSSKEELNNSLKATTQILEELKKTKM 2775
Query: 586 KVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTST 644
Y QL ++ +Q + + + ++LE ++ S L + K +T T
Sbjct: 2776 DNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDT 2834
Score = 39.5 bits (88), Expect = 0.037
Identities = 62/348 (17%), Positives = 153/348 (43%), Gaps = 47/348 (13%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQIQITELELSLDVANKTNIDLQK 353
+NDS K+ +++E +R+ + ++ E ++ L++ TE +L L+ K N + QK
Sbjct: 1889 VNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTE-KLCLE---KDNENKQK 1944
Query: 354 TIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRS 413
I +L+ + + ++++ +L + + + + + +E+ + + L +
Sbjct: 1945 VIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQV 2004
Query: 414 VEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEITKELRIADERYQRVQTE 473
E + +E + L+ L K ++++L + D ++ + E
Sbjct: 2005 AEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSL-----------TKCE 2053
Query: 474 LKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKD 533
L++ + L++E+E +VK E +++ RL E + + + LEA +
Sbjct: 2054 LENQIAQLNKEKELLVK----------ESESLQARLSESDYEKL----NVSKALEAAL-- 2097
Query: 534 MELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQ 593
+E E R + T + + + R ++++ ++ E D+K +++ I ++
Sbjct: 2098 --VEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEK-------------KQLHIAEK- 2141
Query: 594 LAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVT 641
L E+E + +V +REL+ +E+ ++ + +A+ T T
Sbjct: 2142 LKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKT 2189
Score = 35.9 bits (79), Expect = 0.46
Identities = 29/128 (22%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Query: 524 ISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQKNISLLQDSLEKT 583
+ LEA ++ + +++ EK L+++ ++L E+ CE +K + L+
Sbjct: 41 LDSLEAALQKQKQKVENEKTEGTN----LKRENQRLMEI---CESLEKTKQKISHELQVK 93
Query: 584 SQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTS 643
+V+ + QL + ++ ++R + ELE ++ A A+ +L+ + F TT
Sbjct: 94 ESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIF-TTP 152
Query: 644 TVPGSQVY 651
P SQ Y
Sbjct: 153 LTP-SQYY 159
Score = 33.9 bits (74), Expect = 1.8
Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 5/137 (3%)
Query: 472 TELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARI 531
T LK + L E E + K + K S E++VK V +E + N+ GK+ I KLE +
Sbjct: 63 TNLKRENQRLMEICESLEKTKQ-KISHELQVKESQVNFQEGQLNS---GKKQIEKLEQEL 118
Query: 532 KDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQ-KNISLLQDSLEKTSQKVSIY 590
K + EL+ ++ L K Q + S +D EK +++V
Sbjct: 119 KRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEER 178
Query: 591 KRQLAEQEGMSQQSVTR 607
KR AE + + + ++
Sbjct: 179 KRLEAEVKALQAKKASQ 195
Score = 33.5 bits (73), Expect = 2.4
Identities = 37/161 (22%), Positives = 72/161 (44%), Gaps = 14/161 (8%)
Query: 300 QTSIEIEQLNARVVEAETKLK-SEVTRIKKKLQIQITELELSLDVANKTNIDLQKTIKKQ 358
+T E + L + + K + SE + K Q+ + E+SLD N + L+ ++ +
Sbjct: 1161 KTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNK 1220
Query: 359 SLQLTEIQTHYDEVQRQLQV---TLDQYGVAQRRIQSLTG------EVEE--IRGNYEQA 407
L+L E + + +Q +LQ L+ + + Q ++G + EE I G +E +
Sbjct: 1221 ELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELS 1280
Query: 408 LRVKRSVEQQ--YEESQTRVNELTVINVNLSSSKAKIEQEL 446
+ Q + + ++NEL I L + K ++ EL
Sbjct: 1281 TSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTEL 1321
>AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens
cDNA FLJ14799 fis, clone NT2RP4001351, weakly similar to
Human ovarian cancer downregulated myosin heavy chain
homolog ).
Length = 965
Score = 58.8 bits (136), Expect = 6e-08
Identities = 97/424 (22%), Positives = 194/424 (45%), Gaps = 43/424 (10%)
Query: 273 LNQLNE-LKETVKQFDDLSVYILNDSSKQTSI--EIEQLNARVVEAE------TKLKSEV 323
L + N+ L++ ++ +L I +S+ E+E L RV+E E TK +S+
Sbjct: 97 LEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 156
Query: 324 TRIKKKLQIQ---ITELELSLDVANKTNIDLQK---TIKKQSLQLTEIQTHYDEVQRQLQ 377
++KKLQ + EL L ++ K +L+K K + T++ + ++ + +
Sbjct: 157 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 216
Query: 378 VTLDQYGVAQRRIQSLTGEVEEIRGNYEQA-LRVKRSVEQQYEESQTRVNELTVINVNLS 436
L++ V + R++ L E E R E+A L +K + + + V+E + +
Sbjct: 217 DLLNELEVVKSRVKEL--ECSESR--LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIK 272
Query: 437 SSKAKIE---QELAIVAADYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIV---K 490
+ K++ + + ++T++L ++ ++++E++ V +L E++ ++ K
Sbjct: 273 QEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLK 332
Query: 491 IEAVKKS-LEIEVKNISVRL---EEVEANAIVGGKRIISKL----EARIKDMELELDEEK 542
E K S L V + RL EEVE G R S+L + +IK++ LE++ K
Sbjct: 333 SEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLK 392
Query: 543 RR--HAETIK-ILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEG 599
+R E ++ L K E + ++ + +Q + L LE+ +++ + + + E
Sbjct: 393 KRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIA-KNKAIEKGEV 451
Query: 600 MSQQSVTRVRRFQRELEAAEDRADVAESNLSLIRAKHRTFVTTSTVPGSQV-YLVQESRA 658
+SQ++ R RF+ LE A+ R D+ +L H + QV Y V + R
Sbjct: 452 VSQEAELR-HRFR--LEEAKSR-DLKAGVQALKEKIHELMNKEDQLSQLQVDYSVLQQRF 507
Query: 659 LSSE 662
+ E
Sbjct: 508 MEEE 511
Score = 58.0 bits (134), Expect = 1e-07
Identities = 61/270 (22%), Positives = 134/270 (49%), Gaps = 27/270 (10%)
Query: 377 QVTLDQYGVAQRRIQSLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLS 436
Q+ ++Q G+ +++Q LT ++ E E+ L+ ++ + +E + ++ +L V + +
Sbjct: 7 QMHIEQLGLQSQKVQDLTQKLRE----EEEKLK---AITSKSKEDRQKLLKLEVDFEHKA 59
Query: 437 SSKAKIEQELAIVAADYDEITKELRIA-------DERYQRVQTELKHTVEHLHEEQERIV 489
S ++ +E+ A+ + ++LR+ E + L+ E L E +++I
Sbjct: 60 SRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIA 119
Query: 490 KIEAVKKSLEIEVKNISVRLEEVEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETI 549
K E SL EV+N+ R+ E+E G I+K E++ +++ +L EE+ E
Sbjct: 120 KGECGNSSLMAEVENLRKRVLEME-----GKDEEITKTESQCRELRKKLQEEEHHSKE-- 172
Query: 550 KILRKKERQLKEVIIQCEEDQKNISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVR 609
LR + +L++ + + E+ ++ S + E T +++ K + ++ +++ V + R
Sbjct: 173 --LRLEVEKLQKRMSELEKLEEAFS--KSKSECTQLHLNLEKEKNLTKDLLNELEVVKSR 228
Query: 610 RFQRELEAAEDRADVAESNLSLIRAKHRTF 639
+ELE +E R + AE +L K ++F
Sbjct: 229 --VKELECSESRLEKAELSLKDDLTKLKSF 256
Score = 51.6 bits (118), Expect = 9e-06
Identities = 61/348 (17%), Positives = 153/348 (43%), Gaps = 16/348 (4%)
Query: 274 NQLNELKETVKQFDDLSVYILNDSS--KQTSIEIEQLNARVVEAETKLKSEVTRIKKKLQ 331
++ +L +++ +L+ +LN+ K E+E +R+ +AE LK ++T++K
Sbjct: 199 SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 258
Query: 332 IQITELELSLDVANKTNIDLQKTIKKQSLQLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQ 391
+ + E + ++ + + K ++ ++ +++ + + L + ++
Sbjct: 259 MLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 318
Query: 392 SLTGEVEEIRGNYEQALRVKRSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAA 451
+LT E +E+ G + + + + R++ + + ++ +++ EL
Sbjct: 319 NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELT---C 375
Query: 452 DYDEITKELRIADERYQRVQTELKHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLEE 511
D KEL + ER ++ +L+ L + ++ ++E ++ + + +S +LEE
Sbjct: 376 PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 435
Query: 512 VEANAIVGGKRIISKLEARIKDMELELDEEKRRHAETIKILRKKERQLKEVIIQCEEDQK 571
+ K I+K +A I+ E+ E + RH ++ K R LK + +E
Sbjct: 436 I--------KHQIAKNKA-IEKGEVVSQEAELRHR--FRLEEAKSRDLKAGVQALKEKIH 484
Query: 572 NISLLQDSLEKTSQKVSIYKRQLAEQEGMSQQSVTRVRRFQRELEAAE 619
+ +D L + S+ +++ E+E ++ V +ELE ++
Sbjct: 485 ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSK 532
Score = 49.6 bits (113), Expect = 3e-05
Identities = 82/375 (21%), Positives = 162/375 (43%), Gaps = 34/375 (9%)
Query: 294 LNDSSKQTSIEIEQLNARVVEAETKL-KSEVTRIKKKLQIQITELELSLDVANKTNIDLQ 352
L ++ +++ + ++ E KL K EV K + E++ +AN+ + + Q
Sbjct: 23 LTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQ 82
Query: 353 KTIKKQSL-----QLTEIQTHYDEVQRQLQVTLDQYGVAQRRIQSLTGEVEEIR------ 401
+K L +L E + + + +LQ D+ + SL EVE +R
Sbjct: 83 LRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEM 142
Query: 402 -GNYEQALRVK---RSVEQQYEESQTRVNELTVINVNLSSSKAKIEQELAIVAADYDEIT 457
G E+ + + R + ++ +E + EL + L +++E+ + E T
Sbjct: 143 EGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECT 202
Query: 458 KELRIADERYQRVQTEL-------KHTVEHLHEEQERIVKIEAVKKSLEIEVKNISVRLE 510
+L + E+ + + +L K V+ L + R+ K E K ++K+ +V L
Sbjct: 203 -QLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLV 261
Query: 511 EVEANAIVGGKRIISKLEARIKDMELE----LDEEKRRHAETIKILRKKERQLKEVIIQC 566
+ N + K+ K++ K+ ++E +D ++ E+ K+L+ K ++V
Sbjct: 262 DERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLT 321
Query: 567 EEDQKNISLLQDSLEKTSQ---KVSIYKRQLAEQEGMSQQSVTRVR-RFQRELEAAEDRA 622
E + I L+ EK+S+ V + K++L E + ++ +TR R R EL ED
Sbjct: 322 RERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEV-EREITRGRSRKGSELTCPEDN- 379
Query: 623 DVAESNLSLIRAKHR 637
+ E L + R K R
Sbjct: 380 KIKELTLEIERLKKR 394
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.311 0.127 0.331
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 74,427,565
Number of Sequences: 224733
Number of extensions: 2772637
Number of successful extensions: 26114
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 610
Number of HSP's successfully gapped in prelim test: 1927
Number of HSP's that attempted gapping in prelim test: 13124
Number of HSP's gapped (non-prelim): 8467
length of query: 664
length of database: 73,234,838
effective HSP length: 95
effective length of query: 569
effective length of database: 51,885,203
effective search space: 29522680507
effective search space used: 29522680507
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 68 (31.5 bits)
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